# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2489 PF10675.4 GAM16826.1 - 0.22 11.1 4.0 0.69 9.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Agenet PF05641.7 GAM16827.1 - 0.01 15.9 0.2 0.031 14.4 0.1 1.8 1 0 0 1 1 1 0 Agenet domain CAML PF14963.1 GAM16827.1 - 0.011 15.1 11.3 0.016 14.6 7.8 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Peptidase_S64 PF08192.6 GAM16827.1 - 0.012 14.0 22.1 0.014 13.7 15.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 GAM16827.1 - 0.016 14.6 26.7 0.02 14.3 18.5 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 GAM16827.1 - 0.021 13.5 27.7 0.026 13.1 19.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SOBP PF15279.1 GAM16827.1 - 0.046 14.0 20.7 0.073 13.4 14.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF936 PF06075.7 GAM16827.1 - 0.093 11.6 24.8 0.11 11.4 17.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FLO_LFY PF01698.11 GAM16827.1 - 0.095 11.5 12.5 0.13 11.0 8.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Macoilin PF09726.4 GAM16827.1 - 0.11 10.7 38.4 0.15 10.3 26.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 GAM16827.1 - 0.13 10.6 19.9 0.16 10.2 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FimP PF09766.4 GAM16827.1 - 0.22 10.5 12.6 0.047 12.7 6.0 1.7 1 1 1 2 2 2 0 Fms-interacting protein Mem_trans PF03547.13 GAM16827.1 - 0.72 8.0 12.6 1.2 7.3 8.7 1.4 1 0 0 1 1 1 0 Membrane transport protein CDC27 PF09507.5 GAM16827.1 - 5.7 6.0 31.4 8.2 5.5 21.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 adh_short PF00106.20 GAM16829.1 - 6.2e-30 104.3 0.3 9e-30 103.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM16829.1 - 8.6e-26 91.1 0.1 1e-25 90.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM16829.1 - 9.5e-10 38.4 0.1 1.8e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 GAM16829.1 - 0.032 14.5 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 GAM16829.1 - 0.054 12.5 0.1 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 GAM16829.1 - 0.13 11.9 0.1 0.52 9.9 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF914 PF06027.7 GAM16830.1 - 8e-104 347.0 22.4 1.1e-103 346.6 15.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 GAM16830.1 - 1.7e-09 37.0 26.9 2.1e-09 36.7 18.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM16830.1 - 7e-07 29.3 31.1 0.00061 19.8 9.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 GAM16830.1 - 0.00066 19.3 28.3 0.0021 17.7 8.8 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 GAM16830.1 - 0.0011 19.2 7.4 0.0011 19.2 5.1 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter DUF2273 PF10031.4 GAM16830.1 - 0.62 9.7 9.4 0.45 10.1 0.5 3.5 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) Pex24p PF06398.6 GAM16830.1 - 0.82 8.3 6.9 5.6 5.6 0.1 2.6 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin PCI PF01399.22 GAM16831.1 - 3.5e-15 56.1 0.9 2.2e-14 53.6 0.0 2.7 3 0 0 3 3 3 1 PCI domain Tenui_NS3 PF05310.7 GAM16831.1 - 0.021 14.7 0.4 0.047 13.5 0.1 1.8 1 1 1 2 2 2 0 Tenuivirus movement protein Pox_D2 PF04701.8 GAM16831.1 - 0.047 13.6 2.2 0.14 12.1 0.3 2.3 2 0 0 2 2 2 0 Pox virus D2 protein Imm16 PF15565.1 GAM16831.1 - 0.075 12.8 1.6 1.7 8.5 0.0 3.3 2 1 2 4 4 4 0 Immunity protein 16 TehB PF03848.9 GAM16832.1 - 3e-07 29.8 0.0 7.8e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.2 GAM16832.1 - 7.6e-07 29.7 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM16832.1 - 8e-05 22.4 0.0 0.00028 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM16832.1 - 0.00048 19.7 0.0 0.0029 17.2 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_10 PF05971.7 GAM16832.1 - 0.0012 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_25 PF13649.1 GAM16832.1 - 0.0026 18.0 0.0 0.017 15.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 GAM16832.1 - 0.0033 17.7 0.0 0.0067 16.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_26 PF13659.1 GAM16832.1 - 0.0041 17.1 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM16832.1 - 0.0089 16.5 0.0 0.027 14.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain SapB_2 PF03489.12 GAM16832.1 - 0.0092 15.9 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Saposin-like type B, region 2 MTS PF05175.9 GAM16832.1 - 0.022 14.1 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 GAM16832.1 - 0.038 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 GAM16832.1 - 0.093 13.2 0.0 0.32 11.5 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain UBX PF00789.15 GAM16833.1 - 4.1e-10 39.5 0.0 8.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 GAM16833.1 - 0.069 12.8 0.8 0.17 11.6 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function, DUF255 Lip_prot_lig_C PF10437.4 GAM16834.1 - 4e-20 71.2 0.0 7.8e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.14 GAM16834.1 - 3.6e-19 68.9 0.0 6.4e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4433 PF14487.1 GAM16835.1 - 0.038 13.7 0.1 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4433) bZIP_1 PF00170.16 GAM16836.1 - 6.5e-10 38.8 7.1 3.3e-09 36.5 2.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM16836.1 - 2.6e-06 27.1 5.7 2.6e-06 27.1 3.9 2.6 3 0 0 3 3 3 1 Basic region leucine zipper Acetyltransf_11 PF13720.1 GAM16836.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 ORC6 PF05460.8 GAM16836.1 - 0.16 11.0 27.8 0.14 11.2 18.6 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RNA_pol_Rpb4 PF03874.11 GAM16836.1 - 2.8 7.9 8.3 0.57 10.1 1.5 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Sec7 PF01369.15 GAM16837.1 - 7e-28 97.6 2.3 1.5e-27 96.4 1.6 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 GAM16837.1 - 9.2e-26 90.2 8.0 9.2e-26 90.2 5.5 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal VIT1 PF01988.14 GAM16838.1 - 9.4e-57 191.9 5.8 9.4e-57 191.9 4.0 1.9 2 1 0 2 2 2 1 VIT family TRAM_LAG1_CLN8 PF03798.11 GAM16838.1 - 0.0034 16.9 0.2 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 TLC domain DUF4097 PF13349.1 GAM16838.1 - 0.19 11.2 0.0 0.19 11.2 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4097) XK-related PF09815.4 GAM16838.1 - 5.7 5.8 8.8 10 4.9 6.1 1.3 1 0 0 1 1 1 0 XK-related protein DPBB_1 PF03330.13 GAM16839.1 - 9.7e-05 22.2 0.2 0.0005 20.0 0.0 2.2 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 GAM16839.1 - 0.1 12.2 0.1 0.26 10.9 0.1 1.7 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.13 GAM16840.1 - 0.0071 16.3 0.1 0.02 14.8 0.1 1.9 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PsbP PF01789.11 GAM16841.1 - 0.0026 17.2 0.1 0.99 8.8 0.0 3.4 3 0 0 3 3 3 2 PsbP RRM_1 PF00076.17 GAM16842.1 - 5.7e-16 57.9 0.1 8.3e-16 57.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM16842.1 - 1.2e-11 44.3 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM16842.1 - 2.9e-08 33.4 0.1 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_2 PF03446.10 GAM16844.1 - 0.079 12.8 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SpoIIE PF07228.7 GAM16845.1 - 5.7e-10 39.2 0.0 1.3e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 GAM16845.1 - 3.6e-06 26.5 0.1 0.039 13.3 0.0 2.8 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAM16845.1 - 8e-05 22.1 3.1 0.00011 21.6 0.0 2.5 3 0 0 3 3 3 1 Protein phosphatase 2C NDUF_B4 PF07225.7 GAM16846.1 - 0.041 13.6 0.1 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Adap_comp_sub PF00928.16 GAM16847.1 - 5e-23 81.5 0.7 7.8e-23 80.8 0.0 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family CBS PF00571.23 GAM16848.1 - 2.8e-37 126.2 0.8 1.1e-10 41.0 0.0 4.3 4 0 0 4 4 4 4 CBS domain PTEN_C2 PF10409.4 GAM16849.1 - 7.1e-18 64.6 6.6 1.5e-17 63.5 1.8 2.3 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.22 GAM16849.1 - 9.2e-07 28.4 0.1 2.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM16849.1 - 2.6e-06 27.0 0.0 7.7e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM16849.1 - 8.5e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAM16849.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 GAM16849.1 - 0.0056 16.1 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) RNA12 PF10443.4 GAM16850.1 - 2.6e-89 299.7 0.2 6.2e-88 295.1 0.1 2.3 1 1 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 GAM16850.1 - 1.2e-05 24.8 0.0 5.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 GAM16850.1 - 3.2e-05 23.7 1.1 8.5e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_35 PF14516.1 GAM16850.1 - 0.00074 18.2 0.0 0.0019 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 GAM16850.1 - 0.0019 18.3 0.0 0.0055 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM16850.1 - 0.0026 17.7 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 GAM16850.1 - 0.0037 17.6 3.8 0.99 9.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM16850.1 - 0.0082 16.0 0.0 0.043 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 GAM16850.1 - 0.01 14.8 0.0 0.083 11.8 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 GAM16850.1 - 0.022 15.0 0.0 0.087 13.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 GAM16850.1 - 0.15 11.4 0.0 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Methyltransf_16 PF10294.4 GAM16851.1 - 1e-17 64.1 0.1 1.2e-09 37.8 0.1 2.4 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 GAM16851.1 - 0.0031 17.2 0.1 0.075 12.7 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM16851.1 - 2.3 8.7 4.5 2.2 8.8 0.1 2.7 2 1 1 3 3 3 0 Methyltransferase domain Kelch_6 PF13964.1 GAM16852.1 - 2.1e-25 87.7 2.3 0.0001 22.3 0.0 6.7 3 1 3 6 6 6 5 Kelch motif Kelch_1 PF01344.20 GAM16852.1 - 3.2e-19 68.1 4.1 2e-05 23.9 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 GAM16852.1 - 1.5e-16 59.8 1.0 2.4e-05 24.0 0.0 5.4 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM16852.1 - 2.3e-12 46.7 0.0 0.14 12.3 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM16852.1 - 3.5e-10 39.2 1.2 0.13 12.1 0.0 4.6 4 0 0 4 4 4 3 Kelch motif zf-C3HC4_4 PF15227.1 GAM16852.1 - 7.7e-07 28.8 12.4 7.7e-07 28.8 8.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAM16852.1 - 2.8e-06 26.9 8.6 2.8e-06 26.9 6.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Kelch_5 PF13854.1 GAM16852.1 - 4.6e-06 26.4 0.5 0.067 13.1 0.1 3.4 3 0 0 3 3 3 2 Kelch motif zf-B_box PF00643.19 GAM16852.1 - 2.1e-05 24.3 8.2 2.1e-05 24.3 5.7 2.8 2 1 0 2 2 2 1 B-box zinc finger zf-RING_6 PF14835.1 GAM16852.1 - 0.00025 20.7 3.6 0.00025 20.7 2.5 2.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 GAM16852.1 - 0.00028 20.4 10.7 0.00028 20.4 7.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM16852.1 - 0.0003 20.7 10.8 0.0003 20.7 7.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM16852.1 - 0.0063 16.3 9.5 0.0063 16.3 6.6 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM16852.1 - 0.011 15.3 6.4 0.011 15.3 4.5 2.2 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) WHEP-TRS PF00458.15 GAM16852.1 - 0.012 15.2 0.3 0.026 14.1 0.2 1.5 1 0 0 1 1 1 0 WHEP-TRS domain DUF2693 PF10902.3 GAM16852.1 - 0.031 14.1 0.1 1 9.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2693) zf-RING_UBOX PF13445.1 GAM16852.1 - 0.042 13.5 7.4 0.035 13.8 2.6 2.8 1 1 1 2 2 2 0 RING-type zinc-finger Sod_Cu PF00080.15 GAM16853.1 - 7e-17 61.9 0.3 1.1e-16 61.2 0.2 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 GAM16853.1 - 0.00013 22.0 0.3 0.00022 21.2 0.2 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1279 PF06916.8 GAM16854.1 - 3.5e-17 62.4 1.5 7e-17 61.5 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3464 PF11947.3 GAM16854.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RCR PF12273.3 GAM16854.1 - 0.071 13.6 9.7 0.13 12.8 6.7 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PPP4R2 PF09184.6 GAM16854.1 - 0.089 12.3 7.2 0.12 11.8 5.0 1.1 1 0 0 1 1 1 0 PPP4R2 Suf PF05843.9 GAM16854.1 - 0.096 12.3 8.6 0.12 12.1 6.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pneumo_phosprot PF02478.11 GAM16854.1 - 0.55 9.7 2.6 0.72 9.3 1.8 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF4106 PF13388.1 GAM16854.1 - 5.3 5.8 13.1 7.3 5.4 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PRELI PF04707.9 GAM16855.1 - 1.8e-44 151.1 0.0 2.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family Baculo_PEP_C PF04513.7 GAM16855.1 - 0.022 14.5 0.5 0.034 13.9 0.4 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SDH_alpha PF03313.10 GAM16855.1 - 0.082 11.9 0.9 0.12 11.4 0.6 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Phasin PF05597.6 GAM16855.1 - 0.2 11.4 5.3 9.4 6.0 3.7 2.2 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CUE PF02845.11 GAM16857.1 - 3.2e-10 39.2 0.1 6.1e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 CUE domain eIF-1a PF01176.14 GAM16858.1 - 5e-25 86.6 0.1 8.3e-25 85.9 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 XRCC4 PF06632.7 GAM16859.1 - 1.8e-20 73.0 10.6 2.3e-20 72.7 7.3 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 NYD-SP28_assoc PF14775.1 GAM16859.1 - 0.00066 19.3 5.7 0.16 11.7 0.4 2.4 2 0 0 2 2 2 2 Sperm tail C-terminal domain DUF4446 PF14584.1 GAM16859.1 - 0.0098 15.7 2.9 0.82 9.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4446) HALZ PF02183.13 GAM16859.1 - 0.015 14.9 1.0 0.015 14.9 0.7 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 GAM16859.1 - 0.024 14.5 0.4 0.024 14.5 0.3 3.7 3 1 1 4 4 4 0 bZIP transcription factor DUF972 PF06156.8 GAM16859.1 - 0.2 12.0 12.2 2.4 8.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) V-SNARE PF05008.10 GAM16859.1 - 2.2 8.4 15.7 0.87 9.7 6.9 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.10 GAM16859.1 - 2.3 7.7 16.6 0.95 8.9 0.6 3.2 3 0 0 3 3 3 0 Septum formation initiator IncA PF04156.9 GAM16859.1 - 2.5 7.6 15.7 6 6.4 10.9 1.7 1 1 0 1 1 1 0 IncA protein CSTF_C PF14304.1 GAM16859.1 - 2.5 7.4 8.3 0.22 10.8 2.3 1.9 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal DUF1043 PF06295.7 GAM16859.1 - 2.6 7.6 12.7 2.4 7.8 6.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DivIVA PF05103.8 GAM16859.1 - 4.9 7.2 15.9 3.1 7.8 0.2 2.5 1 1 1 2 2 2 0 DivIVA protein Sds3 PF08598.6 GAM16859.1 - 6.4 6.2 21.7 20 4.6 15.0 1.9 1 1 0 1 1 1 0 Sds3-like 6PGD PF00393.14 GAM16860.1 - 2.9e-134 446.8 0.1 3.5e-134 446.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 GAM16860.1 - 5.4e-52 175.9 0.0 7.8e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM16860.1 - 0.11 12.5 0.3 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TPP_enzyme_N PF02776.13 GAM16861.1 - 4.7e-48 162.9 0.0 4e-47 159.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 GAM16861.1 - 1.6e-24 86.2 0.0 3.7e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM16861.1 - 1.9e-16 60.0 0.0 6.7e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CBF PF03914.12 GAM16862.1 - 1.2e-43 148.4 4.5 1.9e-43 147.7 0.1 3.1 2 1 1 3 3 3 1 CBF/Mak21 family zf-C2H2_jaz PF12171.3 GAM16863.1 - 9.8e-10 38.3 2.7 9.8e-10 38.3 1.9 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM16863.1 - 0.014 15.5 0.3 0.02 15.0 0.1 1.4 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 GAM16863.1 - 0.032 14.4 0.8 0.062 13.5 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF3449 PF11931.3 GAM16863.1 - 0.039 13.4 0.1 0.064 12.7 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-DBF PF07535.7 GAM16863.1 - 0.059 13.0 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 DBF zinc finger DUF3505 PF12013.3 GAM16863.1 - 0.23 11.7 1.1 7.4 6.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) Tom22 PF04281.8 GAM16864.1 - 0.013 14.9 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PH PF00169.24 GAM16865.1 - 0.00022 21.3 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM16865.1 - 0.04 14.1 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PAT1 PF09770.4 GAM16865.1 - 0.54 8.4 44.2 0.76 7.9 30.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ZZ PF00569.12 GAM16866.1 - 1.5e-09 37.2 5.1 2.7e-09 36.4 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 GAM16866.1 - 1.7e-06 27.9 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2616 PF11077.3 GAM16866.1 - 0.95 8.9 5.9 2.1 7.8 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2616) DIM1 PF02966.11 GAM16867.1 - 1.5e-66 221.9 0.1 1.7e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 GAM16867.1 - 0.0043 16.7 0.1 0.006 16.2 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 GAM16867.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like COBRA PF04833.10 GAM16869.1 - 0.082 12.6 0.2 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 COBRA-like protein Strumpellin PF10266.4 GAM16870.1 - 0 1489.8 22.9 0 1489.6 15.9 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Pox_MCEL PF03291.11 GAM16871.1 - 7.9e-37 126.8 0.6 1.4e-36 126.0 0.4 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 GAM16871.1 - 1.6e-08 34.2 0.0 3.7e-08 33.0 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM16871.1 - 1.5e-06 28.6 0.0 2.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM16871.1 - 1.2e-05 25.8 0.0 3.5e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM16871.1 - 1.7e-05 25.1 0.0 2.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM16871.1 - 5.5e-05 23.4 0.0 8.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM16871.1 - 0.00042 20.0 0.0 0.0015 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM16871.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM16871.1 - 0.003 17.5 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAM16871.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family HOOK PF05622.7 GAM16872.1 - 2.1e-39 134.9 102.3 2.9e-38 131.2 70.9 2.6 1 1 0 1 1 1 1 HOOK protein ATG16 PF08614.6 GAM16872.1 - 0.012 15.4 21.2 0.012 15.4 14.7 6.6 2 2 3 6 6 6 0 Autophagy protein 16 (ATG16) IncA PF04156.9 GAM16872.1 - 7.7 6.0 118.6 0.072 12.6 19.3 6.1 1 1 3 5 5 5 0 IncA protein PIP5K PF01504.13 GAM16875.1 - 2.3e-21 76.0 14.4 7.9e-20 71.0 10.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SWIB PF02201.13 GAM16876.1 - 7e-14 51.2 1.3 1.1e-13 50.6 0.1 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain Macoilin PF09726.4 GAM16876.1 - 0.19 9.9 3.9 0.26 9.5 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein TMF_TATA_bd PF12325.3 GAM16877.1 - 0.00012 21.7 8.2 0.00012 21.7 5.7 6.1 4 2 3 7 7 7 2 TATA element modulatory factor 1 TATA binding EF-hand_7 PF13499.1 GAM16877.1 - 0.0021 18.1 0.9 0.13 12.4 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM16877.1 - 0.0031 16.6 0.6 0.047 13.0 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 GAM16877.1 - 0.0052 16.5 0.0 0.028 14.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 GAM16877.1 - 0.031 13.6 0.0 0.088 12.1 0.0 1.8 1 0 0 1 1 1 0 EF hand Feld-I_B PF09252.5 GAM16877.1 - 0.05 13.5 1.2 0.19 11.6 0.8 2.0 1 0 0 1 1 1 0 Allergen Fel d I-B chain GST_C_3 PF14497.1 GAM16878.1 - 4e-12 46.4 0.0 7.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM16878.1 - 7.2e-12 45.0 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM16878.1 - 2.4e-07 30.8 0.0 2.1e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM16878.1 - 1.4e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM16878.1 - 0.0032 17.4 0.0 0.022 14.7 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RRM_1 PF00076.17 GAM16879.1 - 5e-38 128.5 0.2 5.2e-16 58.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM16879.1 - 3.9e-28 97.2 0.0 8.2e-11 41.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM16879.1 - 7.8e-21 73.6 0.0 2e-07 30.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 GAM16879.1 - 1.5e-08 34.8 0.0 4.7e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.1 GAM16879.1 - 5.1e-06 26.1 0.2 1.3 8.7 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif PRP38_assoc PF12871.2 GAM16879.1 - 0.0082 16.6 41.9 0.0082 16.6 29.0 4.1 1 1 2 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Nup35_RRM PF05172.8 GAM16879.1 - 0.0083 15.8 0.1 2.1 8.1 0.0 3.1 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 GAM16879.1 - 0.29 9.5 17.3 0.41 9.0 12.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 GAM16879.1 - 4.5 6.3 13.8 8.9 5.4 9.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RasGAP PF00616.14 GAM16880.1 - 1.1e-09 38.2 3.4 2e-08 34.1 0.0 3.4 2 2 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase BAR PF03114.13 GAM16880.1 - 2.5e-05 23.9 10.0 2.5e-05 23.9 6.9 2.1 1 1 1 2 2 2 1 BAR domain DUF387 PF04079.11 GAM16880.1 - 0.028 13.7 0.4 0.087 12.1 0.3 1.8 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Pkinase PF00069.20 GAM16881.1 - 3.1e-73 246.1 0.0 4.7e-73 245.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM16881.1 - 6e-47 159.8 0.0 9.1e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM16881.1 - 2.1e-08 33.4 0.0 1.4e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAM16881.1 - 0.00032 20.5 0.0 0.029 14.1 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM16881.1 - 0.00049 19.2 0.6 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ADP_ribosyl_GH PF03747.9 GAM16882.1 - 7.1e-49 167.1 0.0 8.4e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Corona_S2 PF01601.11 GAM16882.1 - 0.015 13.4 0.1 0.026 12.6 0.1 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PX PF00787.19 GAM16883.1 - 5e-12 45.6 0.6 5e-12 45.6 0.4 2.0 2 0 0 2 2 2 1 PX domain CUE PF02845.11 GAM16883.1 - 0.004 16.6 0.1 0.012 15.1 0.1 1.8 1 0 0 1 1 1 1 CUE domain Kelch_6 PF13964.1 GAM16884.1 - 2.4e-15 55.9 5.7 0.017 15.3 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 GAM16884.1 - 7.1e-14 51.3 5.7 2.6e-06 27.0 0.0 5.7 5 2 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM16884.1 - 2.3e-11 43.5 6.3 0.014 15.5 0.0 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM16884.1 - 4.2e-10 39.0 1.0 0.054 13.0 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 GAM16884.1 - 0.00085 19.0 2.7 6.7 6.6 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Ank PF00023.25 GAM16885.1 - 1.5e-128 412.7 41.5 5.1e-08 32.3 0.0 20.2 20 0 0 20 20 20 19 Ankyrin repeat Ank_2 PF12796.2 GAM16885.1 - 2.6e-127 415.5 28.6 8.1e-17 61.3 0.1 11.0 4 3 7 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM16885.1 - 9e-108 350.9 28.8 9.7e-12 45.0 0.1 16.3 6 5 11 17 17 17 17 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM16885.1 - 2e-100 326.5 39.0 6.9e-11 42.0 0.1 16.2 6 6 9 16 16 16 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM16885.1 - 2.9e-84 268.5 32.8 6e-08 32.1 0.0 20.3 20 0 0 20 20 20 18 Ankyrin repeat IPK PF03770.11 GAM16886.1 - 2.8e-54 183.7 0.1 5.1e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Rad52_Rad22 PF04098.10 GAM16886.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Tim17 PF02466.14 GAM16887.1 - 1.3e-33 115.7 8.0 1.5e-33 115.5 5.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.1 GAM16887.1 - 0.23 11.0 11.6 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 GAM16887.1 - 1.5 8.5 14.3 1 9.0 3.3 2.5 2 0 0 2 2 2 0 Glycine zipper LRR_6 PF13516.1 GAM16888.1 - 9.4e-18 62.2 40.9 0.0032 17.3 0.0 9.9 10 0 0 10 10 10 7 Leucine Rich repeat LRR_4 PF12799.2 GAM16888.1 - 0.0074 15.8 30.4 1.9 8.2 0.0 5.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM16888.1 - 0.34 11.0 19.9 32 5.1 0.0 7.9 5 3 1 6 6 6 0 Leucine Rich Repeat DUF229 PF02995.12 GAM16889.1 - 2.9e-38 131.5 0.2 7.1e-38 130.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.18 GAM16889.1 - 0.00034 19.9 0.0 0.05 12.7 0.0 2.4 1 1 1 2 2 2 2 Sulfatase DUF4271 PF14093.1 GAM16889.1 - 0.19 11.3 14.1 0.15 11.6 8.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) CO_dh PF02552.11 GAM16889.1 - 0.77 9.3 2.6 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Ufd2P_core PF10408.4 GAM16890.1 - 1.4e-179 598.3 18.4 2.6e-179 597.5 12.8 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 GAM16890.1 - 9e-29 99.2 2.6 1.9e-28 98.2 0.9 2.3 2 0 0 2 2 2 1 U-box domain DUF3439 PF11921.3 GAM16890.1 - 7.7e-05 22.4 2.5 0.00019 21.1 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Paramyxo_C PF01692.13 GAM16890.1 - 0.13 11.8 9.2 3.6 7.1 3.8 2.6 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c Mucin PF01456.12 GAM16890.1 - 1.2 8.9 18.5 2.4 7.9 12.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF846 PF05832.7 GAM16891.1 - 0.084 12.5 4.2 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) DUF3995 PF13160.1 GAM16891.1 - 0.58 10.2 2.3 1 9.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Atrophin-1 PF03154.10 GAM16891.1 - 0.76 7.8 5.7 1 7.4 4.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family RhoGAP PF00620.22 GAM16893.1 - 7.3e-40 136.0 2.2 6e-39 133.0 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain CobT PF06213.7 GAM16893.1 - 8.2 5.4 17.1 17 4.3 11.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_S7 PF00177.16 GAM16894.1 - 8.2e-37 126.0 0.3 9.7e-37 125.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RhoGEF PF00621.15 GAM16896.1 - 4.8e-43 147.1 0.4 1.1e-42 146.0 0.3 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM16896.1 - 1e-05 25.6 0.0 3.9e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 GAM16896.1 - 0.022 14.7 0.0 0.022 14.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain K_channel_TID PF07941.6 GAM16896.1 - 0.082 13.1 0.3 0.082 13.1 0.2 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain IQ PF00612.22 GAM16896.1 - 0.16 11.7 1.1 0.35 10.6 0.8 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ribosomal_60s PF00428.14 GAM16896.1 - 4.3 7.8 9.0 2 8.8 3.6 2.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein PC4 PF02229.11 GAM16897.1 - 0.0056 15.8 0.0 0.94 8.7 0.0 2.1 2 0 0 2 2 2 2 Transcriptional Coactivator p15 (PC4) Med24_N PF11277.3 GAM16898.1 - 2.3e-07 28.7 6.0 1e-05 23.3 0.0 2.9 2 1 0 2 2 2 2 Mediator complex subunit 24 N-terminal Peptidase_C1 PF00112.18 GAM16900.1 - 4.6e-54 183.5 4.3 6.1e-54 183.2 3.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 GAM16900.1 - 0.023 13.2 1.1 0.046 12.2 0.3 1.8 2 0 0 2 2 2 0 Peptidase C1-like family DOMON PF03351.12 GAM16901.1 - 7.5e-14 51.7 0.1 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 GAM16901.1 - 2.2e-09 37.2 15.4 2.2e-09 37.2 10.7 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 GAM16901.1 - 0.01 15.4 9.7 0.35 10.4 6.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) UQ_con PF00179.21 GAM16902.1 - 7e-48 161.6 0.0 7.7e-48 161.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM16902.1 - 5.6e-08 32.6 0.0 6.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAM16902.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain bZIP_1 PF00170.16 GAM16903.1 - 1.3e-11 44.3 18.5 3.8e-10 39.5 6.5 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 GAM16903.1 - 1.6e-05 24.5 17.0 2.6e-05 23.9 5.8 2.5 2 0 0 2 2 2 1 Basic region leucine zipper CALCOCO1 PF07888.6 GAM16903.1 - 0.0013 17.1 2.5 0.0013 17.1 1.7 1.6 2 0 0 2 2 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Zip PF02535.17 GAM16903.1 - 0.011 14.7 4.3 0.017 14.1 3.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter HTH_1 PF00126.22 GAM16903.1 - 0.024 14.3 0.2 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family V_ATPase_I PF01496.14 GAM16903.1 - 0.66 7.7 5.3 1.1 7.0 3.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 GAM16903.1 - 0.97 9.3 5.1 1.4 8.8 2.9 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SelP_N PF04592.9 GAM16903.1 - 1.7 8.0 12.5 4.7 6.5 8.7 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1202 PF06717.6 GAM16903.1 - 2 7.6 8.5 4.6 6.4 3.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1202) tRNA-synt_1d PF00750.14 GAM16903.1 - 3.8 6.2 8.5 0.13 11.0 1.8 1.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) CENP-Q PF13094.1 GAM16903.1 - 6.5 6.7 17.3 0.14 12.2 6.1 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med3 PF11593.3 GAM16905.1 - 5.7e-05 22.5 1.4 5.7e-05 22.5 1.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DHHW PF14286.1 GAM16905.1 - 6.1e-05 22.5 0.8 8.6e-05 22.0 0.6 1.2 1 0 0 1 1 1 1 DHHW protein CAF-1_p150 PF11600.3 GAM16905.1 - 0.024 14.0 16.9 0.032 13.6 11.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3292 PF11696.3 GAM16905.1 - 0.025 12.4 3.5 0.035 11.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Coa1 PF08695.5 GAM16905.1 - 0.09 12.2 0.0 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 Presenilin PF01080.12 GAM16905.1 - 0.15 10.8 7.4 0.19 10.5 5.1 1.1 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.7 GAM16905.1 - 0.21 10.2 6.7 0.25 9.9 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein Plasmodium_Vir PF05795.6 GAM16905.1 - 0.59 9.2 4.1 0.91 8.6 2.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1510 PF07423.6 GAM16905.1 - 0.69 9.2 12.7 0.94 8.8 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Suf PF05843.9 GAM16905.1 - 1 9.0 6.1 1.4 8.6 4.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 GAM16905.1 - 1.6 7.0 8.2 2 6.7 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2413 PF10310.4 GAM16905.1 - 2.9 6.5 13.2 4 6.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RR_TM4-6 PF06459.7 GAM16905.1 - 3.5 7.4 12.8 5.3 6.8 8.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 GAM16905.1 - 3.7 6.4 14.9 5.3 5.9 10.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RNase_HII PF01351.13 GAM16908.1 - 8e-38 130.0 10.6 1.8e-21 76.6 0.2 3.4 3 1 1 4 4 4 2 Ribonuclease HII Abhydro_lipase PF04083.11 GAM16909.1 - 1.5e-19 69.0 0.0 3.1e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAM16909.1 - 4.2e-11 42.8 0.1 1.3e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM16909.1 - 3.2e-08 33.7 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM16909.1 - 7.5e-06 25.7 0.0 1e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family SRF-TF PF00319.13 GAM16911.1 - 3.4e-16 58.1 0.2 7e-16 57.2 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Suf PF05843.9 GAM16911.1 - 0.17 11.5 15.6 0.11 12.1 9.6 1.6 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) P16-Arc PF04699.9 GAM16911.1 - 2.2 8.2 5.1 1.4 8.9 2.1 1.7 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) ABC2_membrane_3 PF12698.2 GAM16911.1 - 5.7 5.8 7.0 8.9 5.2 4.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein I_LWEQ PF01608.12 GAM16912.1 - 4.1e-50 169.6 196.3 7.1e-50 168.9 8.1 18.6 6 3 13 20 20 20 12 I/LWEQ domain FERM_M PF00373.13 GAM16912.1 - 5.8e-23 81.4 0.0 5.8e-23 81.4 0.0 3.5 4 0 0 4 4 4 1 FERM central domain FERM_N PF09379.5 GAM16912.1 - 9.8e-18 63.9 0.0 6.8e-17 61.2 0.0 2.4 2 0 0 2 2 2 1 FERM N-terminal domain VHP PF02209.14 GAM16912.1 - 3.2e-13 49.1 0.9 8.4e-13 47.7 0.6 1.8 1 0 0 1 1 1 1 Villin headpiece domain VBS PF08913.5 GAM16912.1 - 1.6e-08 34.8 108.2 0.00013 22.1 4.4 14.1 11 2 1 12 12 12 7 Vinculin Binding Site Chibby PF14645.1 GAM16913.1 - 0.0075 16.1 5.1 0.0082 16.0 2.9 1.5 1 1 0 1 1 1 1 Chibby family Cep57_CLD_2 PF14197.1 GAM16913.1 - 0.018 15.0 2.2 0.021 14.7 0.7 1.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4140 PF13600.1 GAM16913.1 - 0.043 14.2 0.3 0.068 13.6 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 GAM16913.1 - 0.11 12.4 5.2 0.069 13.0 2.2 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.3 GAM16913.1 - 0.15 11.8 1.9 0.26 11.0 0.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.10 GAM16913.1 - 0.15 11.5 1.8 0.24 10.9 1.2 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 GAM16913.1 - 0.17 12.2 2.9 0.2 12.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Lzipper-MIP1 PF14389.1 GAM16913.1 - 0.23 11.5 5.0 0.33 11.0 3.4 1.5 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TMF_DNA_bd PF12329.3 GAM16913.1 - 0.37 10.6 6.1 0.087 12.6 2.2 1.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4363 PF14276.1 GAM16913.1 - 0.82 9.3 3.5 0.85 9.3 0.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF342 PF03961.8 GAM16914.1 - 0.24 9.7 4.9 0.31 9.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Clathrin_lg_ch PF01086.12 GAM16914.1 - 0.36 10.7 6.3 0.52 10.1 4.4 1.2 1 0 0 1 1 1 0 Clathrin light chain IncA PF04156.9 GAM16914.1 - 9.5 5.7 8.0 30 4.1 5.6 1.9 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 GAM16915.1 - 1.2e-80 270.4 0.0 1.3e-80 270.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM16915.1 - 1.1e-34 119.6 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM16915.1 - 0.00068 18.6 0.0 0.0076 15.2 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 GAM16915.1 - 0.0024 16.7 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 2 Seadornavirus VP7 APH PF01636.18 GAM16915.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM16915.1 - 0.08 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM16915.1 - 0.097 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Sporozoite_P67 PF05642.6 GAM16916.1 - 0.37 8.5 10.3 0.38 8.5 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myb_DNA-binding PF00249.26 GAM16917.1 - 4.6e-44 148.2 15.0 4.5e-15 55.4 1.7 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM16917.1 - 1.1e-39 134.2 13.6 9.3e-17 60.8 1.8 4.3 2 1 2 4 4 4 3 Myb-like DNA-binding domain DUF3384 PF11864.3 GAM16917.1 - 2.7e-08 32.7 6.0 0.34 9.3 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF3384) Rap1_C PF11626.3 GAM16917.1 - 0.0024 17.7 5.4 20 5.1 3.7 3.9 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 GAM16917.1 - 0.025 14.3 0.0 3.6 7.4 0.0 3.3 3 0 0 3 3 3 0 Rap1 Myb domain Rubella_E2 PF05749.6 GAM16917.1 - 0.047 12.9 0.9 0.12 11.5 0.6 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Sigma70_r4_2 PF08281.7 GAM16917.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 LRR_6 PF13516.1 GAM16918.1 - 8.9e-17 59.2 23.1 0.023 14.6 0.1 9.9 10 0 0 10 10 10 6 Leucine Rich repeat LRR_1 PF00560.28 GAM16918.1 - 2.9e-05 23.4 24.4 0.35 11.0 0.1 10.2 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_4 PF12799.2 GAM16918.1 - 0.00087 18.8 33.0 0.096 12.3 1.2 6.9 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM16918.1 - 0.0096 15.6 23.7 0.59 9.9 0.1 6.1 7 1 1 8 8 8 4 Leucine rich repeat LRR_7 PF13504.1 GAM16918.1 - 6.8 7.3 19.9 93 3.9 0.0 7.9 9 0 0 9 9 9 0 Leucine rich repeat CIMR PF00878.13 GAM16919.1 - 2e-05 24.4 0.5 2e-05 24.4 0.3 1.7 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 GAM16919.1 - 0.0019 17.6 0.1 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Pkinase_Tyr PF07714.12 GAM16920.1 - 1.1e-55 188.5 0.0 1.9e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM16920.1 - 4.9e-51 173.3 0.0 9.4e-51 172.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM16920.1 - 1.2e-11 44.2 0.0 3.3e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.9 GAM16920.1 - 0.0004 19.9 0.0 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, SH2-like domain Mso1_C PF14477.1 GAM16920.1 - 0.0035 17.6 0.7 0.0035 17.6 0.5 2.5 1 1 1 2 2 2 1 Membrane-polarising domain of Mso1 APH PF01636.18 GAM16920.1 - 0.029 14.1 0.1 0.071 12.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family IBP39 PF11422.3 GAM16920.1 - 0.037 13.5 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Initiator binding protein 39 kDa Cbl_N2 PF02761.9 GAM16920.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain HABP4_PAI-RBP1 PF04774.10 GAM16922.1 - 3.3e-15 56.4 2.5 3.3e-15 56.4 1.7 3.5 2 2 2 4 4 4 2 Hyaluronan / mRNA binding family WD40 PF00400.27 GAM16923.1 - 6.5e-35 117.7 14.7 2.3e-08 33.6 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM16923.1 - 0.0019 17.9 0.0 0.24 11.2 0.0 3.6 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Daxx PF03344.10 GAM16923.1 - 6.5 5.1 22.3 9.9 4.5 15.5 1.2 1 0 0 1 1 1 0 Daxx Family DUF202 PF02656.10 GAM16925.1 - 0.029 14.5 0.6 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF2721 PF11026.3 GAM16925.1 - 0.062 12.9 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF1509 PF07420.6 GAM16925.1 - 0.064 12.5 1.6 0.076 12.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) YrhK PF14145.1 GAM16925.1 - 0.15 11.7 2.4 0.18 11.5 0.3 1.9 2 0 0 2 2 2 0 YrhK-like protein DUF872 PF05915.7 GAM16925.1 - 0.36 10.6 9.8 5.3 6.9 6.8 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF308 PF03729.8 GAM16925.1 - 1.7 8.7 9.1 3.1 7.8 1.2 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Tetraspannin PF00335.15 GAM16925.1 - 4.2 6.5 5.1 0.72 9.0 1.1 1.4 2 0 0 2 2 2 0 Tetraspanin family TatD_DNase PF01026.16 GAM16927.1 - 4.1e-47 160.5 0.0 5.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF1021 PF06257.6 GAM16927.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) PI3_PI4_kinase PF00454.22 GAM16928.1 - 8.9e-34 116.9 2.6 3.3e-33 115.1 0.1 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAM16928.1 - 0.0029 16.8 0.3 0.0075 15.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FNIP PF05725.7 GAM16929.1 - 1.9e-85 280.5 35.2 3.7e-14 52.4 0.0 9.6 6 3 3 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM16929.1 - 2e-05 24.4 3.0 1.1 9.2 0.0 5.3 6 0 0 6 6 6 2 Protein of unknown function (DUF1769) Inhibitor_I78 PF11720.3 GAM16929.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Glyco_hydro_65C PF03633.10 GAM16929.1 - 0.57 10.2 4.7 43 4.2 0.2 4.9 5 0 0 5 5 5 0 Glycosyl hydrolase family 65, C-terminal domain Cofilin_ADF PF00241.15 GAM16930.1 - 6.1e-23 81.0 0.0 6.9e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-DHHC PF01529.15 GAM16931.1 - 1.2e-39 135.5 11.6 2.1e-39 134.7 8.1 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase HemY_N PF07219.8 GAM16931.1 - 0.058 12.9 0.0 3.6 7.1 0.1 2.3 2 0 0 2 2 2 0 HemY protein N-terminus PLATZ PF04640.9 GAM16931.1 - 0.19 11.9 2.9 6 7.1 0.0 2.3 2 0 0 2 2 2 0 PLATZ transcription factor CDP-OH_P_transf PF01066.16 GAM16932.1 - 7.5e-14 51.8 16.8 7.9e-13 48.5 11.7 2.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF2723 PF11028.3 GAM16932.1 - 8.5 5.8 10.8 1.8 8.0 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2723) F-box PF00646.28 GAM16933.1 - 0.016 14.8 0.4 0.05 13.2 0.3 1.9 1 0 0 1 1 1 0 F-box domain Poxvirus_B22R_C PF13168.1 GAM16934.1 - 0.032 13.4 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal BNR PF02012.15 GAM16935.1 - 0.0069 16.0 15.2 34 4.8 0.0 7.2 7 0 0 7 7 7 4 BNR/Asp-box repeat 4HBT PF03061.17 GAM16936.1 - 5.7e-13 48.8 0.1 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 GAM16936.1 - 0.00018 21.3 0.2 0.00027 20.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Aminotran_4 PF01063.14 GAM16937.1 - 2.6e-29 102.3 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Methyltransf_11 PF08241.7 GAM16938.1 - 8.4e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM16938.1 - 1.1e-11 44.6 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM16938.1 - 1.9e-10 41.3 0.0 3.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM16938.1 - 3e-07 30.2 0.1 7e-07 29.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM16938.1 - 6.6e-07 29.7 0.0 6.6e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM16938.1 - 4.4e-06 25.9 0.1 7.9e-06 25.1 0.1 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM16938.1 - 1.4e-05 25.3 0.0 8.2e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 GAM16938.1 - 0.0001 21.8 0.0 0.00024 20.6 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 GAM16938.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 GAM16938.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 GAM16938.1 - 0.025 13.6 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAM16938.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TRAP_alpha PF03896.11 GAM16938.1 - 1.4 7.8 12.4 2.4 7.0 8.6 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Astro_capsid PF03115.9 GAM16938.1 - 1.9 6.6 4.6 2 6.5 3.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 GAM16938.1 - 4.6 6.5 17.1 6.3 6.1 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VCBS PF13517.1 GAM16939.1 - 2.1e-33 114.4 28.7 7.9e-12 45.3 1.9 6.2 3 2 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAM16939.1 - 4.4e-17 61.2 24.9 0.00016 21.2 0.0 8.4 8 1 0 8 8 8 5 FG-GAP repeat UnbV_ASPIC PF07593.7 GAM16939.1 - 2e-12 46.6 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 ASPIC and UnbV Herpes_UL6 PF01763.11 GAM16939.1 - 0.00033 18.9 0.7 0.00048 18.4 0.5 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like TcdB_toxin_midN PF12256.3 GAM16939.1 - 0.068 12.6 1.0 3.2 7.1 0.0 3.6 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region DBB PF14545.1 GAM16939.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, SlyX PF04102.7 GAM16939.1 - 0.78 10.1 4.2 0.29 11.5 0.7 1.9 2 0 0 2 2 2 0 SlyX RabGAP-TBC PF00566.13 GAM16940.1 - 2.1e-39 135.2 0.4 3.3e-39 134.5 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 GAM16940.1 - 6.6e-31 107.4 0.0 9.9e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM16940.1 - 6.6e-19 67.9 0.0 1.5e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.15 GAM16940.1 - 0.0013 19.0 0.0 0.018 15.3 0.0 2.7 2 1 0 2 2 2 1 Rhodanese-like domain Kinase-like PF14531.1 GAM16940.1 - 0.21 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FNIP PF05725.7 GAM16941.1 - 4.9e-61 202.4 13.8 9.6e-13 47.8 0.0 7.8 3 2 3 8 8 8 8 FNIP Repeat EF-hand_1 PF00036.27 GAM16942.1 - 5.6e-23 78.4 0.4 4.1e-05 22.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM16942.1 - 2.9e-20 72.1 0.5 1.1e-08 35.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM16942.1 - 3.6e-19 66.8 1.4 0.00011 21.7 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 GAM16942.1 - 2.1e-16 58.4 0.1 0.00019 20.6 0.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 GAM16942.1 - 3.5e-14 52.1 2.0 0.00062 19.3 0.1 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM16942.1 - 4.3e-11 42.8 0.3 7.6e-06 25.9 0.1 2.7 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM16942.1 - 1.6e-06 27.6 2.9 0.35 10.5 0.0 3.5 1 1 2 3 3 3 3 EF hand EF-hand_9 PF14658.1 GAM16942.1 - 7.8e-06 25.7 0.1 0.0027 17.6 0.0 3.1 3 1 1 4 4 4 1 EF-hand domain EF-hand_4 PF12763.2 GAM16942.1 - 7.4e-05 22.4 0.4 0.0021 17.7 0.1 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand S6PP_C PF08472.5 GAM16942.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal SecA_DEAD PF07517.9 GAM16943.1 - 7.6e-09 35.2 0.0 4.1e-08 32.8 0.0 2.4 1 0 0 1 1 1 1 SecA DEAD-like domain DUF258 PF03193.11 GAM16943.1 - 1.9e-05 23.9 0.4 7.8e-05 21.9 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM16943.1 - 4.2e-05 23.4 0.6 0.00045 20.1 0.2 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAM16943.1 - 0.0014 19.0 1.8 0.033 14.6 0.0 3.7 3 0 0 3 3 3 1 Miro-like protein ABC_tran PF00005.22 GAM16943.1 - 0.0021 18.3 0.9 0.028 14.7 0.2 3.4 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 GAM16943.1 - 0.0023 18.0 0.2 0.068 13.3 0.1 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 GAM16943.1 - 0.0031 17.6 0.0 0.018 15.2 0.0 2.5 1 0 0 1 1 1 1 RNA helicase Helicase_C PF00271.26 GAM16943.1 - 0.011 15.5 0.0 0.082 12.7 0.0 2.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain AAA_17 PF13207.1 GAM16943.1 - 0.014 16.1 0.3 0.075 13.8 0.2 2.4 1 0 0 1 1 1 0 AAA domain HSCB_C PF07743.8 GAM16943.1 - 4.2 7.9 12.6 32 5.0 0.1 6.7 7 1 0 7 7 7 0 HSCB C-terminal oligomerisation domain DUF1515 PF07439.6 GAM16944.1 - 0.086 12.6 1.2 2.4 8.0 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) BCDHK_Adom3 PF10436.4 GAM16944.1 - 0.19 11.2 5.9 5.2 6.5 0.1 3.7 3 1 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Nop14 PF04147.7 GAM16945.1 - 0.00035 18.6 8.5 0.00038 18.5 5.9 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 GAM16945.1 - 0.5 9.6 21.5 0.66 9.1 14.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 GAM16945.1 - 1.3 6.9 19.5 1.6 6.6 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 GAM16945.1 - 2 8.2 8.5 2.9 7.6 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YqfQ PF14181.1 GAM16945.1 - 3.9 7.5 10.8 7 6.6 7.5 1.6 1 0 0 1 1 1 0 YqfQ-like protein RRN3 PF05327.6 GAM16945.1 - 7.8 4.4 11.9 10 4.1 8.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SecA_DEAD PF07517.9 GAM16947.1 - 1e-08 34.7 0.0 4.2e-08 32.7 0.0 2.1 1 0 0 1 1 1 1 SecA DEAD-like domain Helicase_C PF00271.26 GAM16947.1 - 0.011 15.5 0.0 0.055 13.3 0.0 2.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain HSCB_C PF07743.8 GAM16947.1 - 0.9 10.0 10.9 18 5.8 0.4 5.6 5 1 1 6 6 6 0 HSCB C-terminal oligomerisation domain Endotoxin_N PF03945.9 GAM16948.1 - 1.8e-11 43.8 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM16949.1 - 3.3e-14 52.8 0.9 5.2e-14 52.1 0.6 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM16950.1 - 3.5e-13 49.4 0.1 5.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM16951.1 - 1.1e-12 47.8 0.0 1.5e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM16953.1 - 4.4e-10 39.3 0.0 7.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Ribosomal_L32p PF01783.18 GAM16954.1 - 3.5e-10 39.9 12.7 4.5e-10 39.5 8.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Acetone_carb_G PF08882.6 GAM16954.1 - 0.077 13.0 0.7 0.093 12.7 0.5 1.1 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Metallophos PF00149.23 GAM16955.1 - 1.4e-42 145.3 1.1 1.8e-42 144.9 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Exo70 PF03081.10 GAM16956.1 - 9.1e-38 129.9 8.2 1.7e-37 129.0 5.6 1.5 1 0 0 1 1 1 1 Exo70 exocyst complex subunit G2F PF07474.7 GAM16956.1 - 0.0015 17.9 0.1 0.0029 16.9 0.1 1.4 1 0 0 1 1 1 1 G2F domain DASH_Dad2 PF08654.5 GAM16956.1 - 0.0018 18.2 3.0 0.007 16.3 0.3 2.9 2 1 1 3 3 3 1 DASH complex subunit Dad2 LEDGF PF11467.3 GAM16956.1 - 0.44 10.2 7.2 1.5 8.5 0.6 3.0 3 0 0 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) Zip PF02535.17 GAM16957.1 - 3.7e-44 151.0 11.8 5.2e-44 150.5 8.2 1.2 1 1 0 1 1 1 1 ZIP Zinc transporter Far-17a_AIG1 PF04750.9 GAM16959.1 - 2.5e-29 101.8 18.7 3.8e-28 98.0 12.9 2.0 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein RNA_pol_Rpb1_5 PF04998.12 GAM16960.1 - 2.8e-91 305.6 0.0 8.8e-90 300.7 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAM16960.1 - 1.1e-55 188.1 1.7 1.2e-55 187.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAM16960.1 - 6.8e-32 110.3 0.0 2.2e-31 108.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 GAM16960.1 - 3.4e-29 102.1 3.0 3.4e-29 102.1 2.1 3.9 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 GAM16960.1 - 2.5e-23 81.8 0.0 2.5e-23 81.8 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Hid1 PF12722.2 GAM16960.1 - 0.007 14.1 12.9 0.012 13.2 8.9 1.3 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Nop14 PF04147.7 GAM16960.1 - 0.21 9.4 42.4 0.005 14.8 20.5 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 GAM16960.1 - 0.87 8.5 47.4 0.4 9.7 0.3 3.3 3 0 0 3 3 3 0 BUD22 PBP5_C PF07943.8 GAM16961.1 - 0.038 13.9 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain TPR_17 PF13431.1 GAM16962.1 - 0.054 13.7 4.1 6 7.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM16962.1 - 0.068 12.8 0.5 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 TPR repeat GRP PF07172.6 GAM16962.1 - 2.2 8.8 33.9 11 6.5 6.5 3.9 3 0 0 3 3 3 0 Glycine rich protein family Amnionless PF14828.1 GAM16962.1 - 4.4 5.6 5.3 20 3.5 0.0 2.9 3 0 0 3 3 3 0 Amnionless HAMP PF00672.20 GAM16962.1 - 6.8 6.9 12.5 0.81 9.9 0.7 4.0 3 0 0 3 3 3 0 HAMP domain FNIP PF05725.7 GAM16963.1 - 1.6e-33 114.3 12.4 4.8e-13 48.8 0.1 5.8 5 1 1 6 6 6 4 FNIP Repeat DUF1769 PF08588.5 GAM16963.1 - 7.5e-06 25.7 3.3 0.59 10.1 0.0 5.4 2 1 4 6 6 6 2 Protein of unknown function (DUF1769) F-box-like PF12937.2 GAM16963.1 - 0.1 12.3 0.3 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 F-box-like Actin PF00022.14 GAM16964.1 - 9.5e-99 330.4 0.0 1.1e-98 330.2 0.0 1.0 1 0 0 1 1 1 1 Actin tRNA_U5-meth_tr PF05958.6 GAM16965.1 - 1.1e-18 67.1 0.0 3.4e-11 42.4 0.0 2.8 2 1 1 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.11 GAM16965.1 - 0.023 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein HALZ PF02183.13 GAM16966.1 - 0.041 13.6 0.7 0.041 13.6 0.5 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper LMBR1 PF04791.11 GAM16966.1 - 0.46 8.9 12.4 0.037 12.6 1.2 2.3 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF1180 PF06679.7 GAM16966.1 - 0.58 10.0 3.4 1.3 8.8 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF3461 PF11944.3 GAM16966.1 - 0.89 9.3 11.1 3.7 7.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) HisKA_3 PF07730.8 GAM16966.1 - 0.97 9.8 5.8 2.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Histidine kinase GPCR_chapero_1 PF11904.3 GAM16966.1 - 1.5 7.8 15.3 0.3 10.1 7.5 2.0 2 1 0 2 2 2 0 GPCR-chaperone EzrA PF06160.7 GAM16966.1 - 1.6 6.8 19.6 2.3 6.2 13.6 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.4 GAM16966.1 - 2.2 6.9 24.3 76 1.8 16.8 2.1 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Phage_GPO PF05929.6 GAM16966.1 - 2.3 7.3 10.1 2.1 7.5 6.2 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase G-alpha PF00503.15 GAM16968.1 - 1.4e-94 316.9 19.2 2e-94 316.5 13.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM16968.1 - 3e-14 52.6 1.1 2.1e-10 40.1 0.0 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM16968.1 - 7.7e-05 21.9 4.5 0.0013 17.8 0.1 3.0 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region Sds3 PF08598.6 GAM16968.1 - 0.00098 18.7 0.9 0.00098 18.7 0.6 2.2 2 0 0 2 2 2 1 Sds3-like DUF3439 PF11921.3 GAM16968.1 - 0.0021 17.7 6.8 0.0021 17.7 4.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Miro PF08477.8 GAM16968.1 - 0.033 14.6 0.3 4.3 7.8 0.0 3.4 3 1 0 3 3 3 0 Miro-like protein AAA_14 PF13173.1 GAM16968.1 - 0.15 11.9 2.9 0.33 10.8 0.2 2.7 3 0 0 3 3 3 0 AAA domain Mucin PF01456.12 GAM16968.1 - 0.3 10.8 16.7 0.76 9.5 11.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Host_attach PF10116.4 GAM16968.1 - 1.1 9.4 4.7 0.4 10.8 0.8 2.0 2 0 0 2 2 2 0 Protein required for attachment to host cells K_channel_TID PF07941.6 GAM16969.1 - 0.12 12.5 0.8 0.14 12.3 0.5 1.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Topoisom_I PF01028.15 GAM16969.1 - 0.3 10.1 2.1 0.31 10.1 1.5 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core WD40 PF00400.27 GAM16970.1 - 3.2e-22 77.5 12.7 0.00012 21.7 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM16970.1 - 0.00087 18.8 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 GAM16970.1 - 0.006 16.3 0.0 4.7 7.0 0.0 3.4 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region GRAM PF02893.15 GAM16971.1 - 4.8e-13 48.4 0.1 1.1e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 GRAM domain Glycos_transf_2 PF00535.21 GAM16972.1 - 3.4e-27 95.1 0.0 4.4e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM16972.1 - 4.7e-12 46.1 0.0 6.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 GAM16972.1 - 2.2e-05 23.6 0.1 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 GAM16972.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 MFS_1 PF07690.11 GAM16972.1 - 0.16 10.6 1.1 0.21 10.2 0.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ribosomal_L18p PF00861.17 GAM16974.1 - 5.5e-42 142.7 0.1 1.1e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 GAM16974.1 - 1.4e-29 102.4 3.5 1.4e-29 102.4 2.4 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 GAM16974.1 - 0.066 13.2 0.1 0.67 10.0 0.0 2.4 1 1 1 2 2 2 0 Threonine synthase N terminus AIG1 PF04548.11 GAM16974.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family HpaP PF09483.5 GAM16975.1 - 0.53 10.2 6.7 0.77 9.6 4.6 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF566 PF04484.7 GAM16975.1 - 1.5 8.2 4.1 1.8 8.0 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) HSP90 PF00183.13 GAM16976.1 - 4.5e-250 830.5 40.1 5.4e-250 830.3 27.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 GAM16976.1 - 3.8e-09 36.3 0.2 3.8e-09 36.3 0.2 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM16976.1 - 5.2e-09 35.7 0.1 1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prokineticin PF06607.6 GAM16979.1 - 0.006 16.6 2.8 0.006 16.6 1.9 2.7 2 2 1 3 3 3 1 Prokineticin SKG6 PF08693.5 GAM16980.1 - 0.0024 17.1 2.6 0.0048 16.1 1.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_2 PF07974.8 GAM16980.1 - 0.69 10.1 13.0 1.2 9.3 9.0 1.4 1 0 0 1 1 1 0 EGF-like domain Ank_2 PF12796.2 GAM16981.1 - 1.4e-06 28.5 0.4 4.2e-05 23.8 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM16981.1 - 5.6e-05 22.7 0.0 0.28 11.0 0.1 4.3 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAM16981.1 - 0.0021 18.2 0.1 0.93 9.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM16981.1 - 0.0039 17.6 1.1 0.25 11.8 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM16981.1 - 0.017 15.3 0.1 3.2 8.2 0.0 3.3 2 0 0 2 2 2 0 Ankyrin repeat Vault PF01505.13 GAM16983.1 - 6.2e-65 215.0 0.1 1.3e-14 53.9 0.0 6.3 6 0 0 6 6 6 5 Major Vault Protein repeat MVP_shoulder PF11978.3 GAM16983.1 - 1.6e-52 176.3 0.5 3.2e-52 175.3 0.3 1.5 1 0 0 1 1 1 1 Shoulder domain DUF3601 PF12208.3 GAM16983.1 - 0.05 13.5 0.0 11 5.9 0.0 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF3601) DUF1829 PF08862.5 GAM16983.1 - 0.099 12.9 1.1 0.39 11.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF1829 Frizzled PF01534.12 GAM16984.1 - 2.6e-08 33.0 17.8 3.7e-08 32.5 12.4 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.19 GAM16984.1 - 1e-07 31.3 15.4 1e-07 31.3 10.7 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) DUF456 PF04306.8 GAM16984.1 - 2.8 7.9 10.1 1.3 9.0 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF456) TMF_TATA_bd PF12325.3 GAM16985.1 - 4.2e-28 97.5 14.7 4.2e-28 97.5 10.2 8.6 2 1 5 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 GAM16985.1 - 1.2e-17 63.4 12.5 1.2e-17 63.4 8.6 10.0 5 3 6 12 12 12 3 TATA element modulatory factor 1 DNA binding FAT PF02259.18 GAM16986.1 - 1.4e-109 366.3 2.7 1.4e-109 366.3 1.8 3.1 2 1 0 2 2 2 1 FAT domain DUF3385 PF11865.3 GAM16986.1 - 8.2e-63 211.1 0.1 1.3e-58 197.5 0.0 4.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 GAM16986.1 - 1.3e-59 201.4 0.7 2.6e-59 200.5 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 GAM16986.1 - 1.3e-39 134.2 6.4 2.2e-39 133.5 0.2 4.2 4 0 0 4 4 4 1 Rapamycin binding domain HEAT_2 PF13646.1 GAM16986.1 - 1.4e-22 79.7 10.6 4.8e-05 23.5 0.1 9.8 6 2 2 8 8 8 5 HEAT repeats HEAT PF02985.17 GAM16986.1 - 2.2e-17 61.4 12.8 0.067 13.3 0.0 11.3 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 GAM16986.1 - 1.8e-16 60.0 16.5 0.0027 18.1 0.1 12.2 10 1 2 12 12 12 4 HEAT-like repeat FATC PF02260.15 GAM16986.1 - 1.1e-14 53.5 0.3 2.7e-14 52.2 0.2 1.8 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.2 GAM16986.1 - 6.8e-07 29.2 5.4 0.11 12.2 0.0 6.0 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 GAM16986.1 - 2.6e-05 24.5 1.2 14 6.1 0.0 6.4 6 2 1 7 7 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM16986.1 - 0.00049 19.5 0.7 0.033 13.5 0.0 4.3 5 1 0 5 5 5 1 CLASP N terminal TPR_16 PF13432.1 GAM16986.1 - 0.005 17.4 1.0 8.7 7.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM16986.1 - 0.032 14.4 0.3 2.6 8.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM16986.1 - 0.052 13.3 1.0 0.58 10.0 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 GAM16987.1 - 0.023 14.4 0.2 0.023 14.4 0.2 1.8 2 0 0 2 2 2 0 Prefoldin subunit GlnE PF03710.10 GAM16987.1 - 0.061 12.5 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DUF2930 PF11152.3 GAM16987.1 - 0.075 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) LytR_cpsA_psr PF03816.9 GAM16988.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain TRH PF05438.7 GAM16991.1 - 0.048 13.0 2.0 0.074 12.4 1.4 1.3 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) DUF4005 PF13178.1 GAM16991.1 - 1.6 8.9 5.5 0.97 9.6 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4005) Keratin_B2_2 PF13885.1 GAM16992.1 - 9.9 5.9 14.8 65 3.3 10.2 2.2 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein LCM PF04072.9 GAM16993.1 - 7e-37 126.7 0.0 1.2e-36 126.0 0.0 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Peptidase_C39_2 PF13529.1 GAM16996.1 - 2e-18 67.1 0.5 3.1e-18 66.5 0.3 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.10 GAM16996.1 - 9.4e-08 31.9 0.0 6e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase C39 family Guanylate_cyc_2 PF09778.4 GAM16996.1 - 6.3e-05 22.2 0.0 0.055 12.6 0.0 2.2 2 0 0 2 2 2 2 Guanylylate cyclase DUF3335 PF11814.3 GAM16996.1 - 0.0046 16.1 0.0 0.0095 15.0 0.0 1.5 2 0 0 2 2 2 1 Peptidase_C39 like family Transpep_BrtH PF14399.1 GAM16996.1 - 0.0094 15.2 0.0 0.037 13.3 0.0 2.0 1 1 0 1 1 1 1 NlpC/p60-like transpeptidase FNIP PF05725.7 GAM16997.1 - 1.4e-11 44.1 8.2 0.00084 19.2 0.2 5.0 3 1 1 4 4 4 4 FNIP Repeat FNIP PF05725.7 GAM16998.1 - 5.2e-13 48.7 26.2 0.0001 22.2 0.5 6.5 4 2 4 8 8 8 6 FNIP Repeat DUF1693 PF07984.7 GAM16999.1 - 9.6e-21 74.2 2.7 6.3e-17 61.7 1.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1693) WBS_methylT PF12589.3 GAM17000.1 - 5.5e-16 58.8 7.9 9.1e-16 58.1 5.4 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 GAM17000.1 - 1.8e-12 47.5 0.0 3.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM17000.1 - 9.1e-08 32.3 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM17000.1 - 7.8e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM17000.1 - 2.7e-05 24.1 0.0 4.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM17000.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM17000.1 - 0.0001 22.7 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 GAM17000.1 - 0.0036 16.8 0.0 0.1 12.0 0.0 2.2 2 1 0 2 2 2 1 DNA methylase Methyltransf_18 PF12847.2 GAM17000.1 - 0.01 16.4 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM17000.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 GAM17000.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 GAM17000.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Ras PF00071.17 GAM17001.1 - 5.2e-40 136.4 0.0 3.1e-24 85.2 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM17001.1 - 1.1e-14 54.9 0.0 4.5e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein PH PF00169.24 GAM17001.1 - 1.8e-13 50.5 0.4 4.5e-13 49.2 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 GAM17001.1 - 3.3e-05 23.9 0.1 3.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 GAM17001.1 - 7.6e-05 22.3 0.1 0.00016 21.2 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 GAM17001.1 - 0.011 15.9 1.1 0.046 13.9 0.8 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_5 PF15405.1 GAM17001.1 - 0.019 14.9 0.1 0.071 13.0 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain Coatomer_E PF04733.9 GAM17002.1 - 4.5e-95 318.1 6.3 5e-95 318.0 4.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.1 GAM17002.1 - 5.2e-09 36.5 2.1 0.01 16.4 0.0 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM17002.1 - 3.7e-08 32.8 7.1 0.00014 21.3 0.0 4.3 3 1 2 5 5 5 3 TPR repeat TPR_19 PF14559.1 GAM17002.1 - 4.2e-07 30.1 9.7 0.0032 17.7 0.1 4.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM17002.1 - 5.3e-06 26.6 6.3 0.21 12.3 0.0 5.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM17002.1 - 7.7e-06 25.3 2.3 0.46 10.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR_2 PF13041.1 GAM17002.1 - 1.8e-05 24.5 0.0 0.13 12.2 0.0 3.6 3 0 0 3 3 3 1 PPR repeat family TPR_12 PF13424.1 GAM17002.1 - 0.00012 21.9 7.3 0.4 10.6 0.0 4.6 2 1 3 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.3 GAM17002.1 - 0.0005 18.9 3.1 0.02 13.6 0.2 2.2 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 GAM17002.1 - 0.00059 19.9 8.2 0.025 14.6 0.1 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 GAM17002.1 - 0.00063 19.4 11.0 0.18 11.8 0.0 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 GAM17002.1 - 0.0054 16.6 4.9 9.3 6.4 0.0 4.3 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.1 GAM17002.1 - 0.025 14.9 4.3 11 6.7 0.0 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM17002.1 - 0.16 12.5 0.7 8 7.2 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM17002.1 - 0.23 11.3 9.7 0.75 9.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM17002.1 - 0.25 11.6 9.4 2.5 8.4 0.0 5.1 5 1 1 6 6 5 0 Tetratricopeptide repeat CD36 PF01130.16 GAM17003.1 - 3.4e-48 164.1 14.8 6.4e-27 93.9 1.3 2.3 2 0 0 2 2 2 2 CD36 family TraD_N PF12615.3 GAM17003.1 - 0.069 13.5 4.5 0.098 13.0 0.1 3.3 4 0 0 4 4 4 0 F sex factor protein N terminal RXT2_N PF08595.6 GAM17005.1 - 0.0032 17.2 6.5 0.01 15.6 4.5 1.8 1 0 0 1 1 1 1 RXT2-like, N-terminal FAM176 PF14851.1 GAM17005.1 - 0.0052 16.4 2.4 0.014 15.1 1.7 1.7 1 0 0 1 1 1 1 FAM176 family Sigma70_ner PF04546.8 GAM17005.1 - 0.0061 16.2 4.3 0.017 14.7 3.0 1.7 1 0 0 1 1 1 1 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 GAM17005.1 - 0.02 12.7 6.0 0.032 12.1 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tom22 PF04281.8 GAM17005.1 - 0.042 13.3 3.7 0.1 12.0 2.6 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CENP-B_dimeris PF09026.5 GAM17005.1 - 3.6 7.8 17.9 13 6.0 12.4 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 GAM17005.1 - 6.4 5.9 17.2 24 4.0 10.4 2.1 2 0 0 2 2 2 0 NOA36 protein FNIP PF05725.7 GAM17006.1 - 2.4e-62 206.6 14.0 2e-11 43.6 0.3 7.5 5 1 1 7 7 7 6 FNIP Repeat LRR_5 PF13306.1 GAM17006.1 - 1.4e-05 24.8 0.0 0.0068 16.1 0.0 3.7 1 1 2 3 3 3 1 Leucine rich repeats (6 copies) tRNA-synt_1g PF09334.6 GAM17007.1 - 5.1e-118 394.1 0.0 7.4e-118 393.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM17007.1 - 4.4e-21 74.5 3.9 2.3e-11 42.4 0.1 4.3 4 1 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 GAM17007.1 - 2.1e-08 33.6 0.0 0.0026 16.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 GAM17007.1 - 7.9e-08 32.2 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA GST_C PF00043.20 GAM17007.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1846 PF08903.6 GAM17007.1 - 0.19 10.1 0.0 0.3 9.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Uma2 PF05685.7 GAM17008.1 - 0.002 17.5 0.0 0.0047 16.2 0.0 1.6 1 1 1 2 2 2 1 Putative restriction endonuclease Nfu_N PF08712.6 GAM17009.1 - 1.9e-30 104.3 0.1 1.3e-29 101.6 0.0 2.3 3 0 0 3 3 3 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 GAM17009.1 - 4.2e-21 74.4 0.1 7e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Utp13 PF08625.6 GAM17010.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Cbl_N2 PF02761.9 GAM17011.1 - 0.073 13.1 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Ank_2 PF12796.2 GAM17012.1 - 1.4e-13 50.9 0.1 0.13 12.6 0.0 8.0 3 3 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17012.1 - 0.00025 21.0 7.2 50 4.5 0.0 9.8 12 0 0 12 12 12 0 Ankyrin repeat Ank_4 PF13637.1 GAM17012.1 - 0.0026 18.2 5.8 7.5 7.2 0.0 6.9 7 2 2 9 9 9 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM17012.1 - 0.023 14.5 0.0 27 4.8 0.0 5.6 5 1 0 5 5 5 0 Ankyrin repeat PRKCSH-like PF12999.2 GAM17013.1 - 3e-41 140.9 7.4 3e-41 140.9 5.1 2.5 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 GAM17013.1 - 6.8e-30 103.5 0.6 6.8e-30 103.5 0.4 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 GAM17013.1 - 0.0083 16.0 12.2 0.11 12.3 1.9 2.7 1 1 1 2 2 2 2 Low-density lipoprotein receptor domain class A FlaC_arch PF05377.6 GAM17013.1 - 0.016 15.0 3.0 0.52 10.2 0.4 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) D123 PF07065.9 GAM17013.1 - 0.061 12.3 6.3 0.1 11.6 4.4 1.3 1 0 0 1 1 1 0 D123 PRKCSH PF07915.8 GAM17013.1 - 0.075 13.8 1.8 0.075 13.8 1.3 3.0 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein Pilus_CpaD PF09476.5 GAM17013.1 - 0.22 10.9 4.3 0.14 11.6 1.4 1.7 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Exonuc_VII_L PF02601.10 GAM17013.1 - 0.75 8.9 11.8 1.1 8.3 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPV_P10 PF05531.7 GAM17013.1 - 3 8.1 11.2 1 9.6 1.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Sugar_tr PF00083.19 GAM17014.1 - 3.2e-98 329.2 35.5 3.6e-98 329.0 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM17014.1 - 1.3e-28 99.7 41.2 4.9e-27 94.5 20.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 GAM17015.1 - 4.2e-39 131.0 13.0 3.4e-11 42.5 0.2 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM17015.1 - 8.6e-08 32.1 2.9 0.0031 17.2 0.1 3.5 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.16 GAM17015.1 - 0.0066 15.0 0.5 0.14 10.6 0.1 2.3 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region GST_C PF00043.20 GAM17016.1 - 9.7e-12 44.7 0.1 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM17016.1 - 1e-11 44.5 0.0 2.2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM17016.1 - 6.1e-10 38.9 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM17016.1 - 1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM17016.1 - 3.4e-09 36.7 0.1 3.2e-07 30.4 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM17016.1 - 2.4e-07 31.1 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.22 GAM17017.1 - 6.9e-78 256.4 3.5 3.2e-25 87.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAM17017.1 - 6.7e-13 48.5 4.6 1.7e-12 47.3 3.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM17017.1 - 5.3e-12 44.1 4.6 1.2e-06 27.4 0.6 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAM17017.1 - 1e-09 37.4 3.9 1.5e-06 27.6 0.8 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 GAM17017.1 - 6.8e-08 32.0 8.8 1.9e-07 30.5 0.9 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM17017.1 - 2.4e-07 29.7 3.7 1.9e-06 26.9 1.0 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.4 GAM17017.1 - 0.0035 17.3 0.8 0.0056 16.6 0.5 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_S28e PF01200.13 GAM17018.1 - 9.4e-32 108.5 1.2 1e-31 108.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ceramidase_alk PF04734.8 GAM17019.1 - 2.7e-261 868.2 0.0 3.1e-261 868.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase FNIP PF05725.7 GAM17020.1 - 2.2e-108 354.0 24.6 1.8e-13 50.1 0.0 10.7 5 3 1 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM17020.1 - 5.8e-08 32.5 18.1 1 9.3 0.0 10.0 6 5 5 11 11 11 4 Protein of unknown function (DUF1769) Crystallin PF00525.13 GAM17020.1 - 0.095 12.9 0.9 9.5 6.5 0.0 3.7 4 0 0 4 4 4 0 Alpha crystallin A chain, N terminal NPL4 PF05021.10 GAM17021.1 - 4e-47 160.8 0.1 5.7e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family JAB PF01398.16 GAM17021.1 - 3.3e-06 26.8 0.0 6.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0506 PF11703.3 GAM17021.1 - 0.05 13.5 1.3 2.5 8.1 0.1 2.8 3 0 0 3 3 3 0 UPF0506 mono-CXXC PF15626.1 GAM17021.1 - 0.21 11.5 4.6 0.59 10.1 3.2 1.7 1 0 0 1 1 1 0 single CXXC unit WD40 PF00400.27 GAM17023.1 - 7.6e-12 44.6 7.0 0.044 13.6 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PK_C PF02887.11 GAM17023.1 - 0.072 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain DUF4613 PF15390.1 GAM17023.1 - 0.085 11.0 0.1 0.76 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) Gmad1 PF10647.4 GAM17023.1 - 0.13 11.6 0.0 0.76 9.1 0.0 2.1 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Ank_2 PF12796.2 GAM17024.1 - 1.9e-47 159.4 38.0 5.5e-09 36.2 0.0 7.7 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17024.1 - 2.1e-31 107.7 18.4 0.00021 21.7 0.0 10.6 4 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17024.1 - 2.4e-26 91.1 29.7 0.0049 17.0 0.0 15.0 4 2 13 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17024.1 - 6.6e-26 87.7 23.3 0.27 11.6 0.0 16.7 8 5 9 17 17 17 8 Ankyrin repeat Ank PF00023.25 GAM17024.1 - 5.6e-21 73.2 26.7 0.4 10.5 0.0 16.1 15 2 2 17 17 17 6 Ankyrin repeat DUF3447 PF11929.3 GAM17024.1 - 4.7e-07 29.5 4.2 0.6 9.9 0.1 5.8 4 2 2 6 6 6 3 Domain of unknown function (DUF3447) PH PF00169.24 GAM17025.1 - 3.6e-14 52.8 0.4 3.6e-14 52.8 0.3 1.9 2 1 0 2 2 2 1 PH domain SH3_1 PF00018.23 GAM17025.1 - 8.1e-12 44.3 1.1 2e-11 43.0 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 GAM17025.1 - 1.6e-09 37.2 0.1 3.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM17025.1 - 2.7e-07 29.9 0.0 6e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Milton PF12448.3 GAM17025.1 - 3.7e-05 23.9 7.9 6.3e-05 23.2 5.5 1.4 1 0 0 1 1 1 1 Kinesin associated protein PH_11 PF15413.1 GAM17025.1 - 4.1e-05 23.7 2.0 4.1e-05 23.7 1.4 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain TFIIF_alpha PF05793.7 GAM17025.1 - 0.072 11.4 6.7 0.11 10.9 4.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PH_8 PF15409.1 GAM17025.1 - 0.11 12.5 0.4 0.53 10.3 0.3 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain FAM104 PF15434.1 GAM17025.1 - 0.23 11.6 9.7 0.51 10.5 6.7 1.6 1 0 0 1 1 1 0 Family 104 FAM220 PF15487.1 GAM17025.1 - 0.63 9.3 9.1 0.92 8.8 6.3 1.2 1 0 0 1 1 1 0 FAM220 family Atrophin-1 PF03154.10 GAM17025.1 - 1.4 6.9 13.5 1.9 6.5 9.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family BUD22 PF09073.5 GAM17025.1 - 1.5 7.8 10.8 2.2 7.2 7.5 1.1 1 0 0 1 1 1 0 BUD22 7tm_3 PF00003.17 GAM17026.1 - 9.8e-18 64.3 13.0 1.8e-17 63.4 9.0 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR IncA PF04156.9 GAM17026.1 - 0.0052 16.4 5.8 0.0098 15.5 4.0 1.4 1 0 0 1 1 1 1 IncA protein DASH_Spc19 PF08287.6 GAM17027.1 - 0.0035 16.9 14.7 0.02 14.4 3.2 2.7 1 1 1 2 2 2 1 Spc19 Prion PF00377.13 GAM17027.1 - 0.061 13.0 0.6 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Mnd1 PF03962.10 GAM17027.1 - 0.2 11.3 13.1 0.017 14.7 5.6 1.8 2 1 0 2 2 2 0 Mnd1 family Poty_PP PF08440.5 GAM17027.1 - 0.69 8.9 6.8 1.2 8.1 4.7 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein CCDC-167 PF15188.1 GAM17027.1 - 0.84 9.6 6.3 3.1 7.7 4.4 2.0 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.1 GAM17027.1 - 1.1 9.6 4.4 3.2 8.2 1.0 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 GAM17027.1 - 1.6 9.0 13.8 10 6.4 0.7 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 GAM17027.1 - 1.8 6.3 7.5 2 6.1 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 GAM17027.1 - 1.8 7.5 11.5 3 6.8 8.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 GAM17027.1 - 3.3 7.0 8.4 4.6 6.6 3.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF948 PF06103.6 GAM17027.1 - 6.9 6.5 8.3 8.8 6.2 2.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Osmo_CC PF08946.5 GAM17027.1 - 8.5 6.4 10.1 1.6 8.7 0.3 3.0 3 0 0 3 3 2 0 Osmosensory transporter coiled coil DUF1664 PF07889.7 GAM17027.1 - 8.6 6.1 10.2 14 5.4 4.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PspB PF06667.7 GAM17027.1 - 8.9 6.3 7.2 0.39 10.7 0.4 2.1 3 0 0 3 3 3 0 Phage shock protein B MFS_1 PF07690.11 GAM17028.1 - 4.8e-35 120.9 43.9 2.5e-27 95.5 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM17028.1 - 8e-10 37.8 33.7 1.7e-09 36.7 23.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAM17028.1 - 0.15 10.4 45.8 0.011 14.2 7.1 3.7 2 2 1 3 3 3 0 MFS/sugar transport protein ArfGap PF01412.13 GAM17029.1 - 2.1e-35 121.0 0.0 9.7e-35 118.8 0.0 2.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_5 PF13857.1 GAM17029.1 - 1.6e-14 53.5 3.1 4.9e-11 42.5 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM17029.1 - 1.4e-13 50.9 1.2 2.2e-10 40.7 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM17029.1 - 1.6e-13 50.7 0.4 1.1e-11 44.8 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) PH PF00169.24 GAM17029.1 - 1.8e-13 50.5 0.1 5e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 PH domain Ank PF00023.25 GAM17029.1 - 6.8e-11 41.4 4.0 0.0019 17.8 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 GAM17029.1 - 3.9e-08 32.7 1.1 0.1 12.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.1 GAM17029.1 - 1.6e-05 25.0 3.4 0.00014 22.0 0.4 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain FAM92 PF06730.6 GAM17029.1 - 0.029 13.7 4.3 0.057 12.7 3.0 1.4 1 0 0 1 1 1 0 FAM92 protein Syntaxin_2 PF14523.1 GAM17029.1 - 0.1 12.6 0.1 0.1 12.6 0.1 3.3 4 0 0 4 4 4 0 Syntaxin-like protein Phasin_2 PF09361.5 GAM17029.1 - 0.21 11.6 2.2 2.9 7.9 0.2 2.9 2 0 0 2 2 2 0 Phasin protein YlqD PF11068.3 GAM17029.1 - 7.5 6.5 9.9 17 5.4 0.2 2.7 1 1 0 2 2 2 0 YlqD protein RRM_1 PF00076.17 GAM17030.1 - 1.2e-17 63.2 0.3 1.9e-07 30.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17030.1 - 1.6e-14 53.6 0.1 1.6e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17030.1 - 2.9e-14 52.6 0.1 1.1e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.17 GAM17030.1 - 1.3e-12 47.2 0.0 2.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.2 GAM17030.1 - 1.8e-05 24.2 1.9 4.3e-05 23.0 0.1 2.5 2 0 0 2 2 2 1 SUZ-C motif Limkain-b1 PF11608.3 GAM17030.1 - 0.00021 20.9 0.1 0.37 10.5 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.1 GAM17030.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 GAM17030.1 - 0.034 13.8 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain Mannitol_dh_C PF08125.8 GAM17031.1 - 3.9e-67 226.0 0.0 5.1e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 GAM17031.1 - 1.1e-28 100.1 0.1 2.8e-28 98.7 0.0 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain FANCL_C PF11793.3 GAM17031.1 - 0.023 14.6 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain UQ_con PF00179.21 GAM17032.1 - 1.2e-44 151.1 0.1 1.4e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM17032.1 - 0.0015 18.3 0.1 0.0018 18.1 0.1 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 GAM17032.1 - 0.0026 17.4 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAM17032.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 UEV domain 2OG-FeII_Oxy_2 PF13532.1 GAM17033.1 - 5.6e-44 150.2 0.7 3.5e-43 147.6 0.0 2.3 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM17033.1 - 5.1e-05 23.4 0.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UPF0066 PF01980.11 GAM17034.1 - 1.2e-36 125.2 0.0 2.4e-36 124.2 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0066 MBOAT PF03062.14 GAM17035.1 - 4.5e-31 108.1 45.3 1.8e-30 106.1 30.8 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Vinculin PF01044.14 GAM17036.1 - 4.7e-38 130.8 48.8 4.1e-15 54.9 13.4 4.9 2 2 2 4 4 4 4 Vinculin family LcrG PF07216.7 GAM17036.1 - 0.0021 18.0 0.2 0.0021 18.0 0.1 3.1 2 1 0 2 2 2 1 LcrG protein DUF2357 PF09823.4 GAM17036.1 - 0.053 12.6 12.5 0.22 10.6 0.9 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF2357) DUF706 PF05153.10 GAM17036.1 - 0.071 12.4 0.3 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF706) DUF2205 PF10224.4 GAM17036.1 - 0.11 12.0 7.6 0.32 10.5 0.0 4.4 4 0 0 4 4 4 0 Predicted coiled-coil protein (DUF2205) HK97-gp10_like PF04883.7 GAM17036.1 - 7.1 7.6 6.8 5.2 8.0 0.1 3.9 3 1 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component LETM1 PF07766.8 GAM17037.1 - 1.3e-18 67.0 3.4 8.6e-10 38.0 0.0 2.3 1 1 1 2 2 2 2 LETM1-like protein Hydrolase PF00702.21 GAM17038.1 - 4.4e-54 184.1 0.4 9.3e-54 183.0 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM17038.1 - 2.5e-52 177.1 3.5 2.5e-52 177.1 2.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 GAM17038.1 - 5e-21 74.6 0.3 1.3e-10 41.2 0.0 2.9 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 GAM17038.1 - 5e-14 52.9 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM17038.1 - 1.4e-05 24.8 0.6 0.0016 18.0 0.4 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_M24 PF00557.19 GAM17039.1 - 1.8e-41 142.0 0.1 3.2e-41 141.1 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Med3 PF11593.3 GAM17039.1 - 0.11 11.6 5.9 0.2 10.8 4.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2890 PF11081.3 GAM17039.1 - 0.12 12.3 3.8 0.2 11.6 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NST1 PF13945.1 GAM17039.1 - 0.47 10.4 7.9 0.053 13.5 2.4 1.5 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF966 PF06136.8 GAM17039.1 - 1.1 8.5 5.1 2 7.7 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) zf-DBF PF07535.7 GAM17040.1 - 2.9e-19 68.4 1.6 6e-19 67.4 1.1 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_2 PF12756.2 GAM17040.1 - 0.0024 17.9 8.3 0.0033 17.4 4.6 2.1 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Peptidase_M48 PF01435.13 GAM17041.1 - 6.8e-28 97.7 0.2 1.5e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.6 GAM17041.1 - 5.4e-06 25.5 1.1 9.5e-06 24.7 0.5 1.5 2 0 0 2 2 2 1 BlaR1 peptidase M56 DCX PF03607.12 GAM17041.1 - 0.025 14.1 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Doublecortin Steroid_dh PF02544.11 GAM17042.1 - 3e-39 134.1 1.0 3e-39 134.1 0.7 2.3 3 0 0 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 GAM17042.1 - 3e-05 23.3 1.2 0.00018 20.8 0.8 2.0 1 1 0 1 1 1 1 Ubiquitin family PEMT PF04191.8 GAM17042.1 - 6.3e-05 23.0 1.6 0.00013 22.0 0.8 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAM17042.1 - 9.8e-05 21.7 0.8 0.00015 21.1 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FNIP PF05725.7 GAM17043.1 - 2.6e-103 337.7 37.1 3.3e-15 55.7 0.4 10.3 10 0 0 10 10 10 10 FNIP Repeat Coiled PF05710.7 GAM17044.1 - 0.26 11.7 32.5 7.6 7.0 22.5 2.3 1 1 0 1 1 1 0 Coiled coil GRP PF07172.6 GAM17044.1 - 5.5 7.5 12.8 7 7.2 8.9 1.2 1 0 0 1 1 1 0 Glycine rich protein family Lipase_GDSL_2 PF13472.1 GAM17045.1 - 1.1e-10 41.9 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM17045.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MIP PF00230.15 GAM17046.1 - 4.8e-33 114.5 13.7 6.6e-33 114.0 9.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein FNIP PF05725.7 GAM17047.1 - 4.6e-48 160.9 0.2 1.2e-11 44.3 0.4 6.3 3 1 2 6 6 6 6 FNIP Repeat Pkinase PF00069.20 GAM17047.1 - 4.4e-36 124.3 2.9 1.8e-23 83.0 1.8 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17047.1 - 1.4e-17 63.5 0.0 1.4e-14 53.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 GAM17047.1 - 0.0046 16.7 0.0 0.25 11.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Nop14 PF04147.7 GAM17047.1 - 0.046 11.6 4.3 0.081 10.8 3.0 1.3 1 0 0 1 1 1 0 Nop14-like family FNIP PF05725.7 GAM17048.1 - 9.8e-45 150.2 7.6 8e-14 51.3 0.2 4.3 4 0 0 4 4 4 4 FNIP Repeat DUF1769 PF08588.5 GAM17048.1 - 0.0017 18.2 4.5 11 6.0 0.0 5.7 3 2 4 7 7 7 2 Protein of unknown function (DUF1769) Crystallin PF00525.13 GAM17048.1 - 0.0061 16.7 0.5 3.4 7.9 0.1 2.6 2 0 0 2 2 2 2 Alpha crystallin A chain, N terminal Peptidase_C39_2 PF13529.1 GAM17049.1 - 3.2e-19 69.7 4.1 1.8e-09 38.0 0.6 2.2 1 1 1 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.10 GAM17049.1 - 0.0016 18.2 0.9 0.0061 16.3 0.1 2.1 2 0 0 2 2 2 1 Peptidase C39 family Lipase_2 PF01674.13 GAM17049.1 - 0.016 14.5 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 2) GST_C PF00043.20 GAM17050.1 - 6.5e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM17050.1 - 4.6e-11 42.5 0.0 9.9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM17050.1 - 1.7e-09 37.3 0.0 2.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM17050.1 - 3.7e-09 36.6 0.0 7.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM17050.1 - 2.8e-07 30.6 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM17050.1 - 3e-06 27.6 0.1 6.8e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Raptor_N PF14538.1 GAM17051.1 - 8.8e-74 246.4 0.1 2.1e-73 245.2 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 GAM17051.1 - 6.1e-10 38.5 18.4 0.37 10.7 0.7 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat HEAT PF02985.17 GAM17051.1 - 6.8e-08 31.9 6.3 0.23 11.6 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 GAM17051.1 - 5.7e-06 26.5 0.9 0.0071 16.6 0.1 4.2 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 GAM17051.1 - 0.0013 19.1 0.5 0.12 12.8 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 GAM17051.1 - 0.013 15.3 0.0 0.54 10.0 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 GAM17051.1 - 0.067 11.5 0.5 0.71 8.1 0.0 2.2 1 1 2 3 3 3 0 Adaptin N terminal region DUF885 PF05960.6 GAM17052.1 - 2.3e-138 462.8 0.1 2.8e-138 462.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Coiled PF05710.7 GAM17053.1 - 0.61 10.5 17.5 2 8.9 12.1 1.7 1 1 0 1 1 1 0 Coiled coil ABC_membrane PF00664.18 GAM17055.1 - 2.9e-57 194.2 28.9 7e-30 104.3 4.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM17055.1 - 1.5e-42 145.1 0.1 2e-22 79.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 GAM17055.1 - 1.9e-06 27.4 0.1 0.0026 17.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAM17055.1 - 2.7e-06 27.8 0.0 0.067 13.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM17055.1 - 1.7e-05 24.2 2.4 0.0089 15.5 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 GAM17055.1 - 0.00012 21.3 3.3 0.041 13.1 0.1 3.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 GAM17055.1 - 0.00027 20.1 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 GAM17055.1 - 0.00044 20.1 0.5 1.3 8.9 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 GAM17055.1 - 0.00077 18.6 1.0 0.16 11.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 GAM17055.1 - 0.00081 19.4 16.0 0.082 12.8 0.0 4.7 4 1 0 5 5 5 2 AAA domain AAA_16 PF13191.1 GAM17055.1 - 0.0025 17.8 1.1 0.12 12.3 0.4 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 GAM17055.1 - 0.0091 15.4 2.3 1.9 7.8 0.9 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 GAM17055.1 - 0.011 15.8 0.2 2.1 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.9 GAM17055.1 - 0.019 13.0 10.8 0.059 11.3 0.0 2.3 2 0 0 2 2 2 0 CDC45-like protein AAA_23 PF13476.1 GAM17055.1 - 0.021 15.1 19.9 0.012 15.8 4.4 3.5 2 1 1 3 3 3 0 AAA domain MobB PF03205.9 GAM17055.1 - 0.038 13.6 3.2 8.9 6.0 0.1 3.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 GAM17055.1 - 0.086 11.7 0.1 2.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 GAM17055.1 - 0.1 12.0 3.9 0.35 10.2 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 GAM17055.1 - 0.14 12.9 3.9 18 6.1 0.0 3.6 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 GAM17055.1 - 0.25 11.1 8.9 0.2 11.4 0.5 3.4 3 0 0 3 3 3 0 Dynamin family AAA_33 PF13671.1 GAM17055.1 - 0.42 10.4 1.5 4 7.3 0.5 2.3 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.1 GAM17055.1 - 1.8 8.9 20.8 0.59 10.4 4.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 GAM17055.1 - 9.9 5.4 25.5 0.58 9.4 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Acetyltransf_1 PF00583.19 GAM17056.1 - 3.6e-09 36.5 0.0 5.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM17056.1 - 5.6e-07 29.6 0.0 9.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM17056.1 - 0.0011 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM17056.1 - 0.0013 18.6 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM17056.1 - 0.044 13.6 0.0 0.067 13.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 GAM17057.1 - 2.5e-72 243.1 0.0 3.3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17057.1 - 5.4e-34 117.4 0.0 7.4e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAM17057.1 - 3.6e-18 65.4 0.3 1.7e-17 63.2 0.1 2.3 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 GAM17057.1 - 1.1e-10 41.0 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM17057.1 - 0.00048 19.2 0.1 0.001 18.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM17057.1 - 0.01 15.1 0.5 0.019 14.3 0.1 1.6 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 GAM17057.1 - 0.026 14.2 0.3 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 GAM17057.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase YrbL-PhoP_reg PF10707.4 GAM17057.1 - 0.064 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL bPH_4 PF06713.6 GAM17059.1 - 0.038 13.8 0.2 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial PH domain DUF2312 PF10073.4 GAM17059.1 - 0.2 11.0 0.2 0.44 9.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) MOSC PF03473.12 GAM17060.1 - 2.6e-10 39.8 0.0 3.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain FNIP PF05725.7 GAM17062.1 - 1.8e-18 66.1 11.6 0.0022 17.8 0.0 8.5 8 1 0 8 8 8 5 FNIP Repeat Gag_p30 PF02093.11 GAM17062.1 - 0.036 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Gag P30 core shell protein HD PF01966.17 GAM17063.1 - 1.2e-14 54.3 1.9 1.8e-14 53.7 0.5 2.0 2 0 0 2 2 2 1 HD domain AA_permease_2 PF13520.1 GAM17065.1 - 4.3e-46 157.3 50.6 5.7e-46 156.9 35.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM17065.1 - 0.27 9.5 48.3 1 7.5 33.5 1.8 1 1 0 1 1 1 0 Amino acid permease DUF962 PF06127.6 GAM17065.1 - 4.7 7.1 11.2 15 5.5 2.1 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF962) Alpha-amylase PF00128.19 GAM17067.1 - 1.3e-63 215.3 0.1 1.9e-63 214.8 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 GAM17067.1 - 1.9e-05 22.7 0.2 0.02 12.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 70 DUF1966 PF09260.6 GAM17067.1 - 8.3e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL6 PF14871.1 GAM17067.1 - 0.0097 15.9 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 DUF202 PF02656.10 GAM17068.1 - 5.2e-06 26.5 3.3 5.2e-06 26.5 2.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF1218 PF06749.7 GAM17068.1 - 0.00015 22.1 0.8 0.00027 21.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1218) Mito_fiss_reg PF05308.6 GAM17068.1 - 0.014 14.7 1.5 0.019 14.3 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator SpoVA PF03862.8 GAM17068.1 - 0.12 12.4 1.7 0.17 12.0 0.9 1.5 1 1 0 1 1 1 0 SpoVA protein RNA_pol_I_A49 PF06870.7 GAM17069.1 - 5.5e-38 130.5 6.7 8e-38 130.0 4.7 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DHFR_1 PF00186.14 GAM17070.1 - 1.5e-20 73.3 0.0 2.6e-20 72.6 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase RelA_SpoT PF04607.12 GAM17071.1 - 6.9e-27 93.7 0.0 1.4e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins LCM PF04072.9 GAM17073.1 - 1.2e-33 116.2 0.0 2e-33 115.5 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Abi PF02517.11 GAM17074.1 - 2.2e-17 62.9 2.6 2.2e-17 62.9 1.8 2.6 3 1 0 3 3 3 1 CAAX protease self-immunity F-box-like PF12937.2 GAM17075.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like Hexapep PF00132.19 GAM17076.1 - 3.2e-07 29.5 10.2 0.0083 15.5 0.2 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 GAM17076.1 - 1.8e-06 27.4 0.0 3e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase Baculo_p24 PF05073.7 GAM17076.1 - 0.0014 18.2 0.3 0.0036 16.9 0.2 1.8 1 0 0 1 1 1 1 Baculovirus P24 capsid protein NTP_transf_3 PF12804.2 GAM17076.1 - 0.0092 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 GAM17076.1 - 0.022 14.2 9.6 0.37 10.3 0.1 3.7 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF218 PF02698.12 GAM17076.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain NUDIX PF00293.23 GAM17077.1 - 4.9e-17 61.8 0.0 6e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain LRR_6 PF13516.1 GAM17078.1 - 4.7e-32 106.4 53.3 0.00013 21.6 0.1 14.0 15 0 0 15 15 15 10 Leucine Rich repeat LRR_4 PF12799.2 GAM17078.1 - 5.4e-08 32.2 33.8 0.19 11.3 0.2 8.1 5 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM17078.1 - 5.1e-06 26.1 30.3 0.041 13.6 1.6 6.7 3 3 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 GAM17078.1 - 1.1e-05 24.7 22.8 13 6.3 0.0 11.4 12 1 0 12 12 12 1 Leucine Rich Repeat F-box-like PF12937.2 GAM17078.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Methyltransf_2 PF00891.13 GAM17079.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase FeoC PF09012.5 GAM17079.1 - 0.027 14.1 0.8 0.067 12.9 0.6 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator Tox-MPTase4 PF15640.1 GAM17080.1 - 0.03 13.9 0.1 0.097 12.3 0.0 1.8 1 1 1 2 2 2 0 Metallopeptidase toxin 4 F-box PF00646.28 GAM17081.1 - 0.046 13.3 0.9 0.19 11.4 0.7 2.1 1 1 0 1 1 1 0 F-box domain UAA PF08449.6 GAM17083.1 - 1.2e-79 267.4 22.0 1.4e-79 267.2 15.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAM17083.1 - 7.7e-07 28.8 14.5 7.7e-07 28.8 10.0 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAM17083.1 - 1.3e-05 25.2 22.1 0.00033 20.7 7.5 2.8 3 0 0 3 3 3 2 EamA-like transporter family DUF3307 PF11750.3 GAM17083.1 - 0.047 13.4 0.3 0.047 13.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) Nuc_sug_transp PF04142.10 GAM17083.1 - 0.098 11.7 11.3 0.13 11.3 6.4 2.2 1 1 2 3 3 3 0 Nucleotide-sugar transporter EmrE PF13536.1 GAM17083.1 - 0.51 10.5 20.5 0.37 10.9 0.8 3.1 3 0 0 3 3 3 0 Multidrug resistance efflux transporter Peptidase_M20 PF01546.23 GAM17084.1 - 1.5e-34 119.1 0.0 1.9e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM17084.1 - 3.8e-11 42.7 0.0 6.7e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM17084.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Myb_DNA-binding PF00249.26 GAM17085.1 - 5.8e-15 55.0 0.0 1.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM17085.1 - 1.4e-07 31.4 5.6 0.0032 17.5 0.8 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1777 PF08648.7 GAM17086.1 - 4.6e-05 23.2 30.0 5.7e-05 22.9 20.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 GAM17086.1 - 0.0016 16.7 10.1 0.0019 16.4 7.0 1.1 1 0 0 1 1 1 1 Atrophin-1 family MIP-T3 PF10243.4 GAM17086.1 - 0.018 13.5 8.7 0.018 13.5 6.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDRGK PF09756.4 GAM17086.1 - 0.54 9.6 10.7 0.69 9.3 7.5 1.1 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 GAM17086.1 - 6.5 4.6 12.3 6.9 4.5 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 GAM17088.1 - 3.7e-67 226.2 0.1 8.3e-67 225.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17088.1 - 1.6e-34 119.1 0.0 2.5e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM17088.1 - 3.4e-10 39.3 0.0 1.1e-09 37.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 GAM17088.1 - 6.1e-05 22.4 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM17088.1 - 0.00053 19.1 0.1 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM17088.1 - 0.0012 18.2 0.2 0.0012 18.2 0.1 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 GAM17088.1 - 0.13 11.9 0.8 1.5 8.4 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family EST1 PF10374.4 GAM17088.1 - 0.24 11.3 3.7 0.55 10.2 0.5 2.5 2 0 0 2 2 2 0 Telomerase activating protein Est1 GRIM-19 PF06212.7 GAM17088.1 - 0.37 10.5 2.6 0.3 10.8 0.3 2.0 2 0 0 2 2 2 0 GRIM-19 protein WD40 PF00400.27 GAM17090.1 - 5.8e-55 181.3 8.3 6.3e-10 38.5 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat DUF3446 PF11928.3 GAM17090.1 - 0.41 10.8 6.6 1.3 9.2 4.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) AMP-binding PF00501.23 GAM17091.1 - 1.1e-32 112.9 0.0 1.6e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF543 PF04418.7 GAM17091.1 - 0.019 14.9 0.1 0.78 9.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4237 PF14021.1 GAM17091.1 - 0.17 12.1 0.0 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4237) 4HBT PF03061.17 GAM17092.1 - 8.2e-11 41.8 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 GAM17092.1 - 0.00048 19.9 0.0 0.00049 19.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 GAM17092.1 - 0.016 15.1 0.1 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) SUZ PF12752.2 GAM17093.1 - 4.5e-07 30.2 0.9 4.5e-07 30.2 0.6 4.2 3 1 0 3 3 3 1 SUZ domain SUZ-C PF12901.2 GAM17093.1 - 0.026 14.1 4.0 0.17 11.5 2.8 2.4 1 1 0 1 1 1 0 SUZ-C motif Pex26 PF07163.7 GAM17094.1 - 7.8e-06 25.0 3.8 0.00011 21.2 2.5 2.1 1 1 0 1 1 1 1 Pex26 protein WD40 PF00400.27 GAM17095.1 - 5.2e-26 89.5 6.1 1.5e-07 30.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 GAM17095.1 - 0.0071 14.5 0.4 0.11 10.6 0.0 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 GAM17095.1 - 0.13 12.5 0.0 31 4.9 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain MIG-14_Wnt-bd PF06664.7 GAM17096.1 - 3.4e-51 173.8 22.1 3.4e-51 173.8 15.4 1.9 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Myb_DNA-binding PF00249.26 GAM17097.1 - 2.1e-10 40.4 0.0 3.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3362 PF11842.3 GAM17097.1 - 0.9 9.4 9.8 6.3 6.7 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) DUF2547 PF10818.3 GAM17097.1 - 2.9 8.5 12.3 44 4.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Ras PF00071.17 GAM17098.1 - 1.2e-38 132.0 0.0 1.3e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM17098.1 - 2.1e-11 43.3 0.0 2.3e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM17098.1 - 3.7e-09 37.0 0.0 7.3e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 GAM17098.1 - 3.9e-06 26.4 0.1 5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM17098.1 - 0.06 12.4 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.17 GAM17099.1 - 2.9e-41 140.5 0.2 3.4e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17099.1 - 1.5e-17 64.1 0.1 2.2e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17099.1 - 6.5e-15 54.8 0.1 7.6e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM17099.1 - 5.9e-07 29.1 0.5 5.4e-06 25.9 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM17099.1 - 1.4e-05 24.3 0.0 1.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 GAM17099.1 - 0.00029 20.3 0.6 0.00099 18.6 0.4 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 GAM17099.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SR-25 PF10500.4 GAM17100.1 - 0.0022 17.5 12.1 0.0022 17.5 8.4 1.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.1 GAM17100.1 - 0.004 17.4 14.2 0.004 17.4 9.9 1.7 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain VIT1 PF01988.14 GAM17100.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 VIT family CAF-1_p150 PF11600.3 GAM17100.1 - 0.1 11.9 21.5 0.15 11.3 14.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal F420_oxidored PF03807.12 GAM17100.1 - 0.19 12.1 0.6 16 5.9 0.0 3.1 2 2 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3549 PF12069.3 GAM17100.1 - 0.23 10.2 7.0 0.28 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) RR_TM4-6 PF06459.7 GAM17100.1 - 0.27 11.0 15.1 0.48 10.2 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dicty_REP PF05086.7 GAM17100.1 - 1.4 6.5 17.4 2.2 5.9 12.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.3 GAM17100.1 - 1.6 7.2 12.6 0.21 10.1 5.1 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 GAM17100.1 - 1.9 6.4 16.0 2.6 5.9 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 GAM17100.1 - 3.4 5.2 15.4 4.4 4.8 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dsh_C PF12316.3 GAM17100.1 - 3.9 7.5 7.2 5.6 7.0 5.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.12 GAM17100.1 - 6.3 5.5 8.9 8.2 5.1 6.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4613 PF15390.1 GAM17100.1 - 8.7 4.3 10.0 12 3.9 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) NPR3 PF03666.8 GAM17101.1 - 4.9e-63 213.2 7.4 2.9e-32 111.8 0.0 2.1 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 GAM17101.1 - 0.0053 15.5 0.8 0.9 8.1 0.0 2.8 2 1 0 2 2 2 2 Nitrogen permease regulator 2 Perilipin PF03036.11 GAM17102.1 - 6.9e-05 21.8 8.4 0.0009 18.1 5.8 2.4 1 1 0 1 1 1 1 Perilipin family Nbl1_Borealin_N PF10444.4 GAM17102.1 - 0.13 11.6 0.5 8.1 5.8 0.0 3.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal AF0941-like PF14591.1 GAM17102.1 - 0.8 9.7 5.9 4.8 7.2 0.4 3.3 3 0 0 3 3 3 0 AF0941-like Pkinase PF00069.20 GAM17103.1 - 5.1e-76 255.2 0.0 6.5e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17103.1 - 3.6e-47 160.6 0.0 4.8e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM17103.1 - 2.8e-08 33.0 0.0 7.8e-08 31.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like R-HINP1I PF11463.3 GAM17103.1 - 0.001 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 R.HinP1I restriction endonuclease YrbL-PhoP_reg PF10707.4 GAM17103.1 - 0.0087 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 GAM17103.1 - 0.0097 15.2 0.0 0.95 8.7 0.0 2.9 3 0 0 3 3 3 1 RIO1 family DUF3678 PF12435.3 GAM17103.1 - 0.041 13.4 4.4 0.17 11.4 3.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Seadorna_VP7 PF07387.6 GAM17103.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SWIRM PF04433.12 GAM17103.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 SWIRM domain PAT1 PF09770.4 GAM17103.1 - 0.55 8.4 3.1 0.67 8.1 2.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cortexin PF11057.3 GAM17104.1 - 0.2 11.2 1.4 0.3 10.7 1.0 1.3 1 0 0 1 1 1 0 Cortexin of kidney Cpn10 PF00166.16 GAM17105.1 - 9.4e-24 83.1 0.1 1e-23 83.0 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RNA_GG_bind PF10258.4 GAM17105.1 - 0.1 12.3 0.3 4.3 7.0 0.1 2.2 1 1 1 2 2 2 0 PHAX RNA-binding domain Peptidase_S46 PF10459.4 GAM17106.1 - 0.0039 15.6 4.1 0.0054 15.2 2.8 1.1 1 0 0 1 1 1 1 Peptidase S46 Arch_ATPase PF01637.13 GAM17106.1 - 0.011 15.4 1.5 0.011 15.4 1.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase Guanylate_cyc PF00211.15 GAM17106.1 - 0.033 13.5 0.1 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Synaptobrevin PF00957.16 GAM17106.1 - 0.055 13.0 0.6 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Synaptobrevin PPR_2 PF13041.1 GAM17107.1 - 1.9e-53 178.2 11.8 2.3e-13 49.8 0.1 9.7 5 2 5 10 10 10 8 PPR repeat family PPR_3 PF13812.1 GAM17107.1 - 3.5e-38 126.6 0.4 1.6e-06 27.8 0.0 10.5 10 0 0 10 10 10 7 Pentatricopeptide repeat domain GCV_H PF01597.14 GAM17107.1 - 2.3e-37 127.3 0.1 4.8e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein PPR_1 PF12854.2 GAM17107.1 - 3.4e-36 122.4 9.2 5.5e-09 35.3 0.0 8.5 7 1 0 7 7 7 7 PPR repeat PPR PF01535.15 GAM17107.1 - 1.6e-34 115.4 23.2 6.2e-08 32.1 0.0 10.8 10 1 0 10 10 10 7 PPR repeat TPR_14 PF13428.1 GAM17107.1 - 2.1e-05 24.7 0.0 2.2 9.1 0.0 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17107.1 - 5e-05 23.5 0.0 0.6 10.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM17107.1 - 0.00037 20.5 1.0 3.3 7.9 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAM17107.1 - 0.019 15.6 0.0 53 4.6 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat Biotin_lipoyl PF00364.17 GAM17107.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme MBD_C PF14048.1 GAM17107.1 - 0.88 10.2 5.4 2.4 8.8 0.3 2.9 3 0 0 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Fib_alpha PF08702.5 GAM17108.1 - 0.25 11.4 20.5 0.11 12.6 1.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 GAM17108.1 - 0.31 10.6 20.3 0.029 14.0 10.0 1.8 1 1 1 2 2 2 0 Mnd1 family CmcH_NodU PF02543.10 GAM17108.1 - 0.42 9.6 3.4 0.58 9.2 2.4 1.4 1 0 0 1 1 1 0 Carbamoyltransferase CHASE3 PF05227.8 GAM17108.1 - 1.2 8.7 9.9 3.3 7.3 4.1 2.7 1 1 1 2 2 2 0 CHASE3 domain KxDL PF10241.4 GAM17108.1 - 1.4 8.9 16.4 0.11 12.3 3.8 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF2151 PF10221.4 GAM17108.1 - 1.7 6.7 12.4 2 6.4 8.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2762 PF10960.3 GAM17108.1 - 2.6 7.8 12.9 0.12 12.1 3.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) Nup88 PF10168.4 GAM17108.1 - 4.8 4.9 16.5 5.7 4.6 11.5 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF4337 PF14235.1 GAM17108.1 - 5.1 6.9 17.6 2 8.2 4.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Phage_GP20 PF06810.6 GAM17108.1 - 6.2 6.2 26.2 1.8 8.0 9.3 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.14 GAM17108.1 - 7.6 4.2 14.3 9.7 3.9 9.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3810 PF12725.2 GAM17108.1 - 7.7 5.3 9.1 7.6 5.3 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) GP41 PF00517.12 GAM17110.1 - 0.0002 21.0 0.1 0.00021 20.9 0.1 1.0 1 0 0 1 1 1 1 Retroviral envelope protein DUF2360 PF10152.4 GAM17110.1 - 0.00021 21.5 0.6 0.00029 21.1 0.4 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Allexi_40kDa PF05549.6 GAM17110.1 - 0.007 15.6 0.1 0.0078 15.5 0.1 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein HR1 PF02185.11 GAM17110.1 - 0.029 14.0 0.2 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Hr1 repeat NPV_P10 PF05531.7 GAM17110.1 - 0.058 13.6 0.4 0.16 12.2 0.0 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Phasin PF05597.6 GAM17110.1 - 0.097 12.4 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DDE_Tnp_ISAZ013 PF07592.6 GAM17110.1 - 0.11 11.1 0.1 0.11 11.2 0.1 1.0 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DUF4460 PF14687.1 GAM17111.1 - 2e-24 85.5 2.9 2.1e-24 85.4 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 GAM17111.1 - 3.4e-10 39.7 6.2 2.8e-08 33.4 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4461) Ank_2 PF12796.2 GAM17112.1 - 0.039 14.3 0.0 1.9 8.8 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) OST3_OST6 PF04756.8 GAM17114.1 - 4.5e-30 104.3 1.9 6.6e-30 103.7 1.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family EpsG PF14897.1 GAM17114.1 - 0.0095 14.9 4.5 0.011 14.6 3.1 1.1 1 0 0 1 1 1 1 EpsG family Glyco_transf_10 PF00852.14 GAM17115.1 - 3.4e-48 164.0 2.8 5.2e-48 163.4 1.9 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Macoilin PF09726.4 GAM17115.1 - 0.0042 15.4 5.6 0.0043 15.4 3.9 1.1 1 0 0 1 1 1 1 Transmembrane protein BUD22 PF09073.5 GAM17115.1 - 0.55 9.2 17.4 0.82 8.6 12.1 1.2 1 0 0 1 1 1 0 BUD22 Ank_2 PF12796.2 GAM17116.1 - 6.6e-40 135.3 47.5 8.6e-11 42.0 0.8 7.3 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17116.1 - 2.8e-29 100.9 18.8 2.1e-06 28.0 0.3 8.8 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17116.1 - 3.2e-29 100.2 24.3 0.0025 18.0 0.0 12.1 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17116.1 - 2.4e-21 73.6 25.5 0.23 11.7 0.0 13.2 11 3 5 16 16 16 7 Ankyrin repeat Ank PF00023.25 GAM17116.1 - 4.7e-18 64.0 24.9 0.81 9.6 0.2 12.8 13 1 1 14 14 14 9 Ankyrin repeat Rbsn PF11464.3 GAM17116.1 - 0.00013 21.4 0.1 8.3 6.0 0.0 6.2 6 0 0 6 6 6 1 Rabenosyn Rab binding domain DUF2493 PF10686.4 GAM17116.1 - 0.00048 19.6 9.7 0.22 11.0 0.1 5.6 2 2 3 6 6 6 2 Protein of unknown function (DUF2493) DUF4156 PF13698.1 GAM17116.1 - 0.044 13.6 3.0 0.086 12.7 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4156) Vps39_2 PF10367.4 GAM17117.1 - 3e-28 98.1 0.0 3e-28 98.1 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 GAM17117.1 - 6.1e-27 94.7 0.1 1.3e-26 93.6 0.1 1.4 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 GAM17117.1 - 6.2e-20 71.2 1.7 6.2e-20 71.2 1.1 3.4 3 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 GAM17117.1 - 5.7e-14 51.9 13.3 1e-07 31.6 1.5 4.4 4 1 0 4 4 4 2 Region in Clathrin and VPS DUF2175 PF09943.4 GAM17117.1 - 0.00018 21.5 0.7 0.0011 18.9 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) DUF2944 PF11161.3 GAM17117.1 - 0.052 13.2 0.5 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) zf-RING_3 PF14369.1 GAM17117.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 zinc-finger TPR_12 PF13424.1 GAM17117.1 - 0.18 11.7 7.9 3.6 7.5 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FdhE PF04216.7 GAM17117.1 - 0.24 11.0 2.2 0.73 9.5 1.5 1.7 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C2H2_jaz PF12171.3 GAM17117.1 - 0.39 10.9 2.1 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TPR_14 PF13428.1 GAM17117.1 - 2.7 8.8 8.4 33 5.4 0.5 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 GAM17118.1 - 4.4e-86 287.3 60.8 5.4e-48 162.9 15.4 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM17118.1 - 1.6e-50 170.9 0.1 2.7e-24 86.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.1 GAM17118.1 - 5.7e-09 35.9 0.0 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAM17118.1 - 3e-08 33.9 3.1 0.0047 16.9 0.4 4.9 3 2 0 4 4 4 1 AAA domain AAA_16 PF13191.1 GAM17118.1 - 5e-08 33.1 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM17118.1 - 8.5e-08 31.6 0.4 0.0018 17.5 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM17118.1 - 1.1e-07 31.5 0.0 0.013 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM17118.1 - 1.2e-07 31.1 0.0 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 GAM17118.1 - 2.6e-06 26.7 0.0 0.37 9.7 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 GAM17118.1 - 3.6e-06 27.1 0.0 0.071 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 GAM17118.1 - 6.5e-06 26.3 0.0 0.0078 16.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 GAM17118.1 - 1.2e-05 24.7 0.1 0.0028 17.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain PDR_CDR PF06422.7 GAM17118.1 - 4.2e-05 23.1 0.9 0.012 15.2 0.1 2.6 2 0 0 2 2 2 1 CDR ABC transporter AAA_18 PF13238.1 GAM17118.1 - 4.6e-05 23.7 0.0 0.24 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM17118.1 - 4.8e-05 23.3 0.1 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM17118.1 - 6e-05 23.8 0.3 0.12 13.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain PDR_assoc PF08370.6 GAM17118.1 - 0.00012 21.4 1.9 0.17 11.4 0.2 3.3 2 0 0 2 2 2 2 Plant PDR ABC transporter associated RNA_helicase PF00910.17 GAM17118.1 - 0.00018 21.6 0.0 0.79 9.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.1 GAM17118.1 - 0.00019 21.3 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 GAM17118.1 - 0.00023 20.7 0.2 0.25 10.9 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 GAM17118.1 - 0.00026 20.4 0.0 0.36 10.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein MMR_HSR1 PF01926.18 GAM17118.1 - 0.00039 20.3 0.0 0.68 9.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 GAM17118.1 - 0.00051 19.8 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase NACHT PF05729.7 GAM17118.1 - 0.00086 18.9 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain Rad17 PF03215.10 GAM17118.1 - 0.0013 17.5 0.1 0.95 8.0 0.0 2.6 3 0 0 3 3 2 2 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 GAM17118.1 - 0.0014 18.3 0.6 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 GAM17118.1 - 0.0015 17.4 0.4 0.021 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 GAM17118.1 - 0.0022 17.1 0.3 0.24 10.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.14 GAM17118.1 - 0.0036 16.7 0.1 1.1 8.6 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 GAM17118.1 - 0.0056 16.3 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 GAM17118.1 - 0.0079 16.5 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 GAM17118.1 - 0.0082 15.2 58.7 0.0068 15.4 17.2 3.2 2 1 1 3 3 3 1 ABC-2 family transporter protein PduV-EutP PF10662.4 GAM17118.1 - 0.01 15.3 0.3 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 GAM17118.1 - 0.012 15.2 0.0 5.8 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAM17118.1 - 0.023 15.1 0.0 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 GAM17118.1 - 0.047 13.2 0.4 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 GAM17118.1 - 0.057 13.3 0.0 9.7 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF3954 PF13128.1 GAM17118.1 - 0.1 12.0 0.0 4.1 6.8 0.0 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF3954) AAA_10 PF12846.2 GAM17118.1 - 0.12 11.8 0.2 5 6.4 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.17 GAM17118.1 - 0.16 11.4 0.3 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ArgK PF03308.11 GAM17118.1 - 0.16 10.6 0.5 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 GAM17118.1 - 0.17 11.1 0.1 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Mg_chelatase PF01078.16 GAM17118.1 - 0.36 9.9 1.6 3.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI XRCC1_N PF01834.11 GAM17119.1 - 2.1e-23 82.4 1.7 2.3e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 XRCC1 N terminal domain BRCT PF00533.21 GAM17119.1 - 1.2e-12 47.7 0.0 3.6e-05 23.8 0.0 3.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM17119.1 - 4.7e-05 23.1 0.0 0.0004 20.1 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain ADH_zinc_N PF00107.21 GAM17120.1 - 1.8e-30 105.1 0.0 2.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM17120.1 - 1.1e-17 65.1 0.0 2.9e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM17120.1 - 6.4e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.20 GAM17120.1 - 0.0025 17.1 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.14 GAM17120.1 - 0.072 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM17120.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Alpha_kinase PF02816.13 GAM17121.1 - 1.1e-56 191.5 0.2 1.6e-56 190.9 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 GAM17121.1 - 3.1e-28 96.5 7.7 1.9e-06 27.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAM17121.1 - 1.7e-06 26.4 4.8 0.017 13.2 0.3 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAM17121.1 - 0.00088 17.6 0.1 0.43 8.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF1830 PF08865.6 GAM17121.1 - 0.033 13.8 0.0 14 5.4 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1830) GST_N PF02798.15 GAM17122.1 - 9.4e-10 38.5 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM17122.1 - 8.4e-06 26.2 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM17122.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM17122.1 - 0.0014 18.4 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FNIP PF05725.7 GAM17124.1 - 4.4e-70 231.4 18.2 9.4e-12 44.6 0.1 9.4 9 0 0 9 9 9 8 FNIP Repeat Polysacc_deac_1 PF01522.16 GAM17125.1 - 2.1e-24 85.5 0.1 7.5e-22 77.2 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide deacetylase FAM60A PF15396.1 GAM17125.1 - 2.9 7.5 10.8 0.72 9.5 0.7 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Suf PF05843.9 GAM17125.1 - 8.3 6.0 13.3 0.44 10.2 0.2 2.4 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4112 PF13430.1 GAM17127.1 - 0.043 13.7 0.0 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Ank_2 PF12796.2 GAM17128.1 - 0.013 15.7 0.0 2.7 8.3 0.0 3.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DNA_pol_viral_N PF00242.12 GAM17129.1 - 1.7 7.5 9.3 1.8 7.5 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 GAM17129.1 - 9.8 4.3 10.6 9.8 4.3 7.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Ank_2 PF12796.2 GAM17131.1 - 0.019 15.3 0.3 14 6.0 0.1 4.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM17137.1 - 4.4e-05 23.7 1.2 0.26 11.6 0.1 4.6 3 2 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17137.1 - 0.00029 20.7 0.2 27 5.3 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat RE_MjaI PF09568.5 GAM17137.1 - 0.033 13.7 0.6 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 MjaI restriction endonuclease Ank PF00023.25 GAM17137.1 - 0.04 13.7 0.4 75 3.4 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat MMS19_N PF14500.1 GAM17138.1 - 0.00077 18.8 0.4 0.0012 18.1 0.3 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II DEAD PF00270.24 GAM17139.1 - 1e-21 77.1 2.1 2.2e-21 76.0 0.8 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM17139.1 - 4.3e-15 55.3 0.0 1.2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAM17139.1 - 0.011 14.2 0.1 0.095 11.0 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) ketoacyl-synt PF00109.21 GAM17140.1 - 2.3e-76 256.6 2.4 8e-76 254.8 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM17140.1 - 2e-62 211.3 0.0 4.1e-62 210.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM17140.1 - 1.5e-45 155.5 0.0 2.9e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAM17140.1 - 4.2e-38 130.8 0.6 1.4e-37 129.1 0.4 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM17140.1 - 5.5e-34 117.4 1.9 5.5e-34 117.4 1.3 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM17140.1 - 2.1e-33 114.7 0.2 8.5e-33 112.7 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_C PF02797.10 GAM17140.1 - 8.3e-25 87.4 0.5 2.9e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain ADH_zinc_N PF00107.21 GAM17140.1 - 3.9e-20 71.7 0.0 1.5e-19 69.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Chal_sti_synt_N PF00195.14 GAM17140.1 - 9.3e-20 70.8 1.1 1.5e-19 70.1 0.2 1.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 GAM17140.1 - 3.6e-14 52.5 2.5 4.1e-14 52.3 0.3 2.0 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ADH_zinc_N_2 PF13602.1 GAM17140.1 - 1.2e-10 42.3 0.0 7.4e-10 39.8 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM17140.1 - 5.1e-09 35.8 0.1 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 GAM17140.1 - 1.4e-08 34.9 0.3 3.7e-08 33.5 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ACP_syn_III_C PF08541.5 GAM17140.1 - 2.6e-07 30.5 1.0 9.4e-05 22.3 0.0 3.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.18 GAM17140.1 - 7.7e-06 25.0 0.0 7.7e-06 25.0 0.0 2.9 3 0 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM17140.1 - 0.00091 18.8 8.3 0.0027 17.3 0.4 3.7 3 1 0 3 3 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_6 PF12697.2 GAM17140.1 - 0.16 11.8 0.1 0.52 10.1 0.1 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family Trp_halogenase PF04820.9 GAM17141.1 - 2.5e-10 39.5 0.0 2.9e-06 26.1 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 GAM17141.1 - 0.00018 20.5 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM17141.1 - 0.0036 17.3 0.0 0.0081 16.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM17141.1 - 0.0048 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 GAM17141.1 - 0.0074 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM17141.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM17141.1 - 0.044 12.6 0.1 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAM17141.1 - 0.1 11.6 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 GAM17141.1 - 0.11 11.2 0.3 0.19 10.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 GAM17141.1 - 0.14 11.2 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 GAM17141.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.17 GAM17142.1 - 2.2e-05 23.9 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17142.1 - 0.0081 16.1 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17143.1 - 0.03 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_S8 PF00082.17 GAM17144.1 - 2.1e-36 125.5 9.3 2.9e-36 125.0 6.5 1.2 1 0 0 1 1 1 1 Subtilase family Lamp PF01299.12 GAM17144.1 - 0.0098 15.0 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 1 Lysosome-associated membrane glycoprotein (Lamp) Metallophos PF00149.23 GAM17146.1 - 3.8e-15 55.8 1.4 3.8e-15 55.8 1.0 1.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Rad1 PF02144.11 GAM17148.1 - 3.5e-48 163.7 0.4 7.5e-48 162.6 0.3 1.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 GAM17148.1 - 0.00034 19.6 0.0 0.052 12.4 0.0 2.1 1 1 1 2 2 2 2 Hus1-like protein Pkinase PF00069.20 GAM17149.1 - 7.2e-44 149.8 0.0 7.2e-44 149.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17149.1 - 3.6e-22 78.6 0.0 3.6e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PS_Dcarbxylase PF02666.10 GAM17150.1 - 1.1e-64 217.4 0.0 1.5e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Rhabdo_ncap PF00945.13 GAM17150.1 - 0.025 13.1 1.0 0.039 12.5 0.7 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein SprA-related PF12118.3 GAM17150.1 - 0.22 10.8 13.6 0.3 10.3 9.4 1.1 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.10 GAM17150.1 - 0.72 8.4 2.4 0.96 8.0 1.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Inhibitor_I71 PF12628.2 GAM17150.1 - 3.7 7.1 7.3 0.19 11.3 0.3 2.2 3 0 0 3 3 3 0 Falstatin, cysteine peptidase inhibitor cNMP_binding PF00027.24 GAM17152.1 - 1.6e-51 172.0 0.1 7.4e-26 89.8 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 7TMR-HDED PF07697.6 GAM17152.1 - 0.00062 19.5 0.1 1 9.0 0.1 2.4 2 0 0 2 2 2 2 7TM-HD extracellular Cupin_3 PF05899.7 GAM17152.1 - 0.028 13.7 1.1 0.092 12.1 0.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF861) Cupin_2 PF07883.6 GAM17152.1 - 0.17 11.4 3.5 0.21 11.1 0.1 2.6 3 1 0 3 3 3 0 Cupin domain Adaptin_N PF01602.15 GAM17153.1 - 4.5e-125 417.9 17.5 6.1e-125 417.5 12.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region BLVR PF06375.6 GAM17153.1 - 2e-09 37.4 4.4 0.00014 21.6 0.1 2.7 1 1 1 2 2 2 2 Bovine leukaemia virus receptor (BLVR) Cnd1 PF12717.2 GAM17153.1 - 8.5e-05 22.4 4.9 0.16 11.8 0.1 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAM17153.1 - 0.00029 21.0 0.1 0.35 11.1 0.0 3.8 2 1 2 4 4 4 3 HEAT repeats DUF2435 PF10363.4 GAM17153.1 - 0.00038 20.2 0.7 0.58 10.0 0.0 3.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) HEAT PF02985.17 GAM17153.1 - 0.00056 19.7 7.5 0.49 10.6 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat RasGEF_N_2 PF14663.1 GAM17153.1 - 0.011 15.6 0.1 2.6 8.0 0.0 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Alpha_adaptinC2 PF02883.15 GAM17153.1 - 0.014 15.7 0.2 0.048 13.9 0.1 1.9 1 1 0 1 1 1 0 Adaptin C-terminal domain NPCBM_assoc PF10633.4 GAM17153.1 - 0.017 15.1 0.2 0.045 13.8 0.2 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.3 GAM17153.1 - 0.05 13.7 0.8 0.26 11.4 0.1 2.6 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase E1-E2_ATPase PF00122.15 GAM17154.1 - 1.9e-58 197.2 4.0 1.9e-58 197.2 2.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM17154.1 - 5e-26 92.4 0.8 6.6e-26 92.0 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM17154.1 - 1.6e-14 53.0 0.0 3.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM17154.1 - 1.1e-12 48.5 0.1 3e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM17154.1 - 0.00021 20.9 0.3 0.00098 18.7 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM17154.1 - 0.00076 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Myosin_head PF00063.16 GAM17155.1 - 4.5e-240 798.4 2.9 4.5e-240 798.4 2.0 4.3 2 1 1 4 4 3 1 Myosin head (motor domain) DIL PF01843.14 GAM17155.1 - 3.7e-18 65.3 0.0 3.7e-18 65.3 0.0 4.9 3 1 1 4 4 4 1 DIL domain IQ PF00612.22 GAM17155.1 - 8.6e-17 59.1 31.2 2.7e-06 26.5 0.3 6.6 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.14 GAM17155.1 - 0.0032 17.0 0.0 0.0083 15.7 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF1664 PF07889.7 GAM17155.1 - 0.0043 16.8 3.9 0.0043 16.8 2.7 10.0 3 2 5 11 11 11 2 Protein of unknown function (DUF1664) DUF3586 PF12131.3 GAM17156.1 - 3.3 7.8 21.2 0.24 11.4 3.3 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3586) DSPc PF00782.15 GAM17158.1 - 5.1e-08 32.5 0.0 2.6e-07 30.3 0.0 2.2 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAM17158.1 - 0.00059 20.1 0.0 0.00087 19.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family LPAM_1 PF08139.7 GAM17158.1 - 0.31 11.3 2.1 0.51 10.6 1.4 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Pkinase PF00069.20 GAM17159.1 - 3.1e-70 236.2 0.0 5.3e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17159.1 - 7.4e-33 113.7 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM17159.1 - 7.9e-05 21.7 0.0 0.0016 17.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like BAF1_ABF1 PF04684.8 GAM17159.1 - 5.9 5.6 10.8 11 4.7 7.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GFO_IDH_MocA PF01408.17 GAM17160.1 - 4.1e-24 85.3 0.1 6.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 GAM17160.1 - 1.2e-06 28.2 0.0 3.4e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain PH_5 PF15405.1 GAM17160.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Kelch_6 PF13964.1 GAM17161.1 - 2.4e-12 46.4 4.8 0.00033 20.6 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM17161.1 - 4.3e-08 32.7 3.0 0.0023 17.6 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM17161.1 - 0.0059 16.3 0.9 0.5 10.2 0.0 3.4 2 1 1 3 3 3 1 Kelch motif Kelch_1 PF01344.20 GAM17161.1 - 0.0059 16.1 0.3 1.4 8.5 0.1 2.7 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 GAM17161.1 - 0.014 15.3 5.2 9.8 6.2 0.6 3.5 3 0 0 3 3 3 0 Kelch motif DUF3246 PF11596.3 GAM17161.1 - 0.035 13.3 0.5 0.051 12.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Rax2 PF12768.2 GAM17161.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Kelch_3 PF13415.1 GAM17161.1 - 0.039 14.1 0.7 11 6.3 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain HAP2-GCS1 PF10699.4 GAM17162.1 - 5.3e-12 45.4 0.2 1.1e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Male gamete fusion factor TIG PF01833.19 GAM17163.1 - 1.9e-24 85.4 62.9 4e-08 33.1 4.0 8.4 7 2 1 8 8 8 7 IPT/TIG domain DUF4448 PF14610.1 GAM17163.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PilN PF05137.8 GAM17163.1 - 0.48 10.2 5.6 19 5.1 0.0 4.6 6 0 0 6 6 6 0 Fimbrial assembly protein (PilN) HCBP_related PF06594.6 GAM17163.1 - 1.6 8.4 9.7 28 4.4 0.0 5.3 6 0 0 6 6 6 0 Haemolysin-type calcium binding protein related domain SLT PF01464.15 GAM17164.1 - 3.1e-08 33.1 0.0 5.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 GAM17164.1 - 0.0024 17.8 4.3 0.036 14.0 3.0 2.2 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family PALP PF00291.20 GAM17165.1 - 1.2e-72 244.6 0.1 1.4e-72 244.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 GAM17165.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Ribosomal_S7e PF01251.13 GAM17166.1 - 6.1e-77 257.3 4.6 7.1e-77 257.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e SAM_MT PF04445.8 GAM17168.1 - 1.6e-40 138.7 0.0 2.3e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Methyltransf_26 PF13659.1 GAM17168.1 - 5.8e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Toxin_40 PF15520.1 GAM17168.1 - 0.02 14.3 0.4 0.37 10.2 0.2 2.3 2 0 0 2 2 2 0 Putative toxin 40 Methyltransf_18 PF12847.2 GAM17168.1 - 0.023 15.2 0.0 0.048 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAM17168.1 - 0.059 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FGase PF05013.7 GAM17169.1 - 0.035 13.9 4.2 0.056 13.3 2.9 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase PAT1 PF09770.4 GAM17169.1 - 4.2 5.4 25.3 5.1 5.2 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ubiquitin PF00240.18 GAM17170.1 - 1.2e-164 533.9 41.3 2.8e-33 113.1 0.6 8.0 6 2 2 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.3 GAM17170.1 - 1.3e-90 297.1 31.7 2.3e-18 65.6 0.4 8.0 6 2 2 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM17170.1 - 2.6e-27 94.9 13.8 0.00035 20.7 0.1 7.5 6 4 0 6 6 6 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM17170.1 - 9.6e-18 64.3 6.9 0.0069 16.1 0.0 5.9 5 2 0 6 6 6 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM17170.1 - 4e-16 58.8 4.0 0.27 11.1 0.0 6.3 6 3 0 6 6 6 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM17170.1 - 3.1e-14 52.9 2.1 0.46 10.7 0.0 5.2 1 1 4 5 5 5 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM17170.1 - 4.5e-13 49.0 0.0 2.3 8.3 0.0 5.9 6 0 0 6 6 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 GAM17170.1 - 2.1e-08 33.5 4.2 2.8 7.0 0.0 5.1 5 0 0 5 5 5 4 RNA methyltransferase Big_3_3 PF13750.1 GAM17170.1 - 4.5e-07 29.4 0.2 19 4.6 0.0 5.8 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 GAM17170.1 - 2.6e-06 27.2 4.6 7.3 6.5 0.0 4.7 4 0 0 4 4 4 0 GLUT4 regulating protein TUG Corona_NS2A PF05213.7 GAM17170.1 - 4.7e-05 22.8 0.1 21 4.3 0.0 4.5 4 2 2 6 6 6 0 Coronavirus NS2A protein IGR PF09597.5 GAM17170.1 - 0.00016 21.4 0.1 51 3.8 0.0 4.4 4 0 0 4 4 4 0 IGR protein motif Plexin_cytopl PF08337.7 GAM17170.1 - 0.00039 18.8 12.9 6.8 4.8 0.1 6.7 5 4 3 8 8 8 0 Plexin cytoplasmic RasGAP domain DUF3435 PF11917.3 GAM17170.1 - 0.0032 16.2 0.5 36 2.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) CpeS PF09367.5 GAM17170.1 - 0.0054 16.6 4.0 44 3.9 0.0 5.4 5 1 1 6 6 6 0 CpeS-like protein FlgD_ig PF13860.1 GAM17170.1 - 0.0065 16.1 4.9 58 3.5 0.0 4.7 5 0 0 5 5 5 0 FlgD Ig-like domain Plug_translocon PF10559.4 GAM17170.1 - 0.049 13.1 0.0 28 4.3 0.0 4.3 5 0 0 5 5 5 0 Plug domain of Sec61p DUF3809 PF12723.2 GAM17170.1 - 0.084 12.7 0.0 2e+02 1.8 0.0 4.7 5 1 1 6 6 6 0 Protein of unknown function (DUF3809) DUF3642 PF12182.3 GAM17170.1 - 0.1 13.0 14.3 59 4.1 0.0 6.0 6 0 0 6 6 6 0 Bacterial lipoprotein CTDII PF01556.13 GAM17170.1 - 0.23 11.4 26.2 15 5.5 0.4 6.0 3 2 2 6 6 6 0 DnaJ C terminal domain DUF3781 PF12636.2 GAM17170.1 - 0.47 10.4 5.2 1.6e+02 2.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) GABP-alpha PF11620.3 GAM17170.1 - 0.89 9.5 8.9 89 3.1 0.0 4.7 6 0 0 6 6 4 0 GA-binding protein alpha chain Choline_transpo PF04515.7 GAM17171.1 - 9.8e-106 353.2 33.5 9.8e-106 353.2 23.2 1.6 2 0 0 2 2 2 1 Plasma-membrane choline transporter NUDIX PF00293.23 GAM17172.1 - 7.7e-08 32.0 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NIPSNAP PF07978.8 GAM17173.1 - 9.7e-39 131.4 0.0 8.1e-20 70.7 0.0 2.0 2 0 0 2 2 2 2 NIPSNAP Microtub_assoc PF07989.6 GAM17175.1 - 0.00047 19.9 0.3 0.0008 19.1 0.2 1.5 1 0 0 1 1 1 1 Microtubule associated HALZ PF02183.13 GAM17175.1 - 0.00055 19.5 1.4 0.00071 19.2 0.2 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 GAM17175.1 - 0.00095 18.9 1.0 0.0022 17.7 0.7 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 GAM17175.1 - 0.0014 18.5 0.7 0.0014 18.5 0.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.10 GAM17175.1 - 0.0019 17.6 0.6 0.0037 16.7 0.4 1.5 1 0 0 1 1 1 1 Septum formation initiator Matrilin_ccoil PF10393.4 GAM17175.1 - 0.0021 17.3 0.9 0.0021 17.3 0.6 1.6 2 0 0 2 2 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Seryl_tRNA_N PF02403.17 GAM17175.1 - 0.0028 17.6 1.8 0.0033 17.3 1.2 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 GAM17175.1 - 0.0039 15.8 1.3 0.0041 15.8 0.9 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Phasin PF05597.6 GAM17175.1 - 0.0057 16.4 1.2 0.0063 16.2 0.8 1.3 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) IncA PF04156.9 GAM17175.1 - 0.016 14.8 0.3 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 IncA protein DivIVA PF05103.8 GAM17175.1 - 0.033 14.2 0.2 0.033 14.2 0.1 1.5 2 1 0 2 2 2 0 DivIVA protein TSC22 PF01166.13 GAM17175.1 - 0.034 14.1 1.0 3.2 7.7 0.1 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 GAM17175.1 - 0.04 13.7 2.5 0.059 13.2 1.8 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 GAM17175.1 - 0.04 13.4 2.5 0.13 11.7 0.7 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps39_1 PF10366.4 GAM17175.1 - 0.049 13.6 0.2 0.054 13.5 0.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 DUF2205 PF10224.4 GAM17175.1 - 0.056 13.0 0.2 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_2 PF07716.10 GAM17175.1 - 0.067 13.0 0.6 0.15 11.9 0.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Uds1 PF15456.1 GAM17175.1 - 0.068 13.1 0.3 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Up-regulated During Septation CCDC155 PF14662.1 GAM17175.1 - 0.072 12.6 1.9 0.068 12.7 1.0 1.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 SF-assemblin PF06705.6 GAM17175.1 - 0.073 12.2 1.0 0.076 12.1 0.7 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin FlaC_arch PF05377.6 GAM17175.1 - 0.076 12.9 2.7 0.13 12.1 0.2 2.2 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF730 PF05325.6 GAM17175.1 - 0.078 12.7 0.1 0.099 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF730) Shugoshin_N PF07558.6 GAM17175.1 - 0.087 12.5 1.9 7.2 6.4 0.0 2.3 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region Ax_dynein_light PF10211.4 GAM17175.1 - 0.09 12.6 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain BLOC1_2 PF10046.4 GAM17175.1 - 0.11 12.6 1.4 1.9 8.6 0.2 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 GAM17175.1 - 0.12 12.7 1.6 0.24 11.7 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 GAM17175.1 - 0.13 12.0 0.4 0.2 11.4 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-Q PF13094.1 GAM17175.1 - 0.18 11.8 1.6 0.21 11.5 0.8 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin PF02996.12 GAM17175.1 - 0.22 11.1 2.1 0.81 9.3 0.3 2.1 2 1 0 2 2 2 0 Prefoldin subunit DUF972 PF06156.8 GAM17175.1 - 0.25 11.7 1.6 0.48 10.8 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA PF00004.24 GAM17177.1 - 3.9e-45 153.3 0.0 1.2e-44 151.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM17177.1 - 2.2e-09 37.1 0.1 6.7e-09 35.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAM17177.1 - 1.9e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM17177.1 - 5.1e-07 29.8 0.0 1.3e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM17177.1 - 8.9e-07 29.1 0.6 0.0002 21.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM17177.1 - 5.2e-05 22.4 0.0 0.0002 20.4 0.0 2.0 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAM17177.1 - 6.8e-05 23.6 0.0 0.00052 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM17177.1 - 8.6e-05 21.5 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 GAM17177.1 - 0.00016 21.3 0.1 0.00049 19.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAM17177.1 - 0.0003 20.6 0.0 0.0017 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAM17177.1 - 0.00034 20.0 1.5 0.0071 15.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 GAM17177.1 - 0.00043 19.1 0.0 0.00073 18.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 GAM17177.1 - 0.00045 19.6 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 GAM17177.1 - 0.00051 20.0 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 GAM17177.1 - 0.00076 18.9 0.1 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAM17177.1 - 0.0013 17.9 0.0 0.0029 16.8 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAM17177.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 GAM17177.1 - 0.0016 18.0 0.1 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM17177.1 - 0.0017 18.6 0.0 0.0064 16.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 GAM17177.1 - 0.0019 17.8 0.1 0.049 13.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 GAM17177.1 - 0.0039 16.3 0.0 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 GAM17177.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAM17177.1 - 0.0078 15.8 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 GAM17177.1 - 0.012 15.3 0.1 0.091 12.4 0.0 2.4 2 1 0 2 2 2 0 NTPase UPF0079 PF02367.12 GAM17177.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 GAM17177.1 - 0.015 14.1 0.0 0.037 12.9 0.0 1.6 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 GAM17177.1 - 0.017 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.9 GAM17177.1 - 0.021 13.1 0.1 0.03 12.6 0.1 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue KaiC PF06745.8 GAM17177.1 - 0.021 13.9 0.6 0.41 9.7 0.0 2.7 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.17 GAM17177.1 - 0.025 13.4 0.1 0.094 11.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 GAM17177.1 - 0.05 13.2 0.0 0.26 10.9 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_11 PF13086.1 GAM17177.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 GAM17177.1 - 0.071 13.1 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.11 GAM17177.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Rab5ip PF07019.7 GAM17178.1 - 2.9e-21 75.3 4.0 4.6e-21 74.7 2.8 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) YjgP_YjgQ PF03739.9 GAM17178.1 - 0.044 12.5 1.1 0.052 12.2 0.8 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Peptidase_U40 PF10464.4 GAM17178.1 - 0.089 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase U40 UPF0449 PF15136.1 GAM17179.1 - 3.4e-05 23.9 0.3 6.5e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0449 Latarcin PF10279.4 GAM17179.1 - 0.1 12.7 1.0 0.13 12.5 0.7 1.2 1 0 0 1 1 1 0 Latarcin precursor DUF919 PF06034.6 GAM17179.1 - 0.47 10.0 3.9 0.35 10.5 1.1 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Cyclin_N PF00134.18 GAM17180.1 - 0.00026 20.5 0.5 0.00026 20.5 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAM17180.1 - 0.00083 19.7 0.7 0.00083 19.7 0.5 1.9 2 0 0 2 2 2 1 Cyclin Activator_LAG-3 PF11498.3 GAM17180.1 - 0.73 8.5 14.9 1.2 7.8 10.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Response_reg PF00072.19 GAM17181.1 - 3e-40 136.7 1.4 5.5e-28 97.2 0.4 3.6 3 0 0 3 3 3 3 Response regulator receiver domain HATPase_c PF02518.21 GAM17181.1 - 1.6e-25 88.9 0.5 3.6e-25 87.8 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM17181.1 - 3.2e-17 62.2 0.2 9.1e-17 60.8 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 GAM17181.1 - 6e-13 49.0 0.0 1.8e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 GAM17181.1 - 1.6e-05 24.6 0.0 0.00011 21.9 0.0 2.4 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.5 GAM17181.1 - 1.6e-05 24.8 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 GAM17181.1 - 0.0014 18.6 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold SIP1 PF04938.7 GAM17183.1 - 5.5e-49 166.6 0.1 6.9e-49 166.2 0.1 1.0 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Tuberin PF03542.11 GAM17183.1 - 0.13 11.3 0.1 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Tuberin Caudal_act PF04731.7 GAM17183.1 - 0.14 12.4 5.7 0.23 11.7 3.9 1.4 1 1 0 1 1 1 0 Caudal like protein activation region Chlam_PMP PF02415.12 GAM17184.1 - 0.086 13.1 58.1 0.39 11.0 0.1 9.9 10 1 0 10 10 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat CBF PF03914.12 GAM17185.1 - 3.7e-35 120.7 0.7 3.7e-35 120.7 0.5 2.7 2 1 1 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.15 GAM17185.1 - 0.0014 17.0 11.6 0.017 13.4 0.9 2.8 2 1 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.17 GAM17185.1 - 0.0037 17.2 0.2 0.42 10.8 0.0 3.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 GAM17185.1 - 0.01 16.1 0.1 0.094 13.0 0.1 2.7 2 1 0 2 2 2 0 HEAT repeats DUF4629 PF15442.1 GAM17185.1 - 5.3 7.1 26.1 19 5.3 18.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) WD40 PF00400.27 GAM17186.1 - 4e-53 175.5 29.9 2.4e-10 39.8 0.4 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Rootletin PF15035.1 GAM17186.1 - 5.5e-07 29.7 1.7 8.4e-07 29.1 1.2 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion PQQ_3 PF13570.1 GAM17186.1 - 2.4e-06 27.6 4.2 0.47 10.8 0.0 6.1 7 1 0 7 7 6 1 PQQ-like domain zf-C3HC4_2 PF13923.1 GAM17186.1 - 5.2e-06 26.3 2.6 5.2e-06 26.3 1.8 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM17186.1 - 1.1e-05 25.2 1.8 1.1e-05 25.2 1.2 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 GAM17186.1 - 1.2e-05 24.7 0.9 4.7e-05 22.8 0.6 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 GAM17186.1 - 1.7e-05 24.4 2.4 1.7e-05 24.4 1.7 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.3 GAM17186.1 - 2.4e-05 22.6 4.6 0.074 11.1 0.2 3.7 3 1 0 3 3 3 2 Nucleoporin Nup120/160 zf-RING_5 PF14634.1 GAM17186.1 - 6.4e-05 22.6 2.3 6.4e-05 22.6 1.6 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.13 GAM17186.1 - 8.1e-05 22.9 10.5 0.00033 20.9 7.3 2.2 1 0 0 1 1 1 1 TRAF-type zinc finger UBN2 PF14223.1 GAM17186.1 - 0.00011 21.9 2.0 0.00023 20.9 1.4 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-RING_UBOX PF13445.1 GAM17186.1 - 0.00028 20.5 2.4 0.0018 17.9 1.7 2.6 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 GAM17186.1 - 0.00054 19.8 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 1 1 U-box domain Sina PF03145.11 GAM17186.1 - 0.00063 19.4 11.5 0.0079 15.8 1.0 2.5 1 1 1 2 2 2 1 Seven in absentia protein family CCDC144C PF14915.1 GAM17186.1 - 0.0028 16.6 6.7 0.0038 16.1 4.7 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region CPSF_A PF03178.10 GAM17186.1 - 0.0042 16.2 0.1 14 4.6 0.0 4.1 1 1 4 5 5 5 0 CPSF A subunit region zf-RING_2 PF13639.1 GAM17186.1 - 0.0048 16.6 1.9 0.0048 16.6 1.3 3.3 3 0 0 3 3 2 1 Ring finger domain Exonuc_VII_L PF02601.10 GAM17186.1 - 0.02 14.1 0.2 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2051 PF09738.4 GAM17186.1 - 0.091 12.0 5.7 0.041 13.1 1.9 1.7 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) DUF2968 PF11180.3 GAM17186.1 - 0.1 12.0 2.4 0.14 11.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIVA PF05103.8 GAM17186.1 - 0.13 12.2 3.9 0.21 11.6 2.7 1.2 1 0 0 1 1 1 0 DivIVA protein Phage_GP20 PF06810.6 GAM17186.1 - 0.25 10.7 5.1 0.4 10.0 3.6 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 GAM17186.1 - 0.45 10.0 5.0 0.25 10.8 1.3 2.0 1 1 1 2 2 2 0 Septum formation initiator Syntaxin PF00804.20 GAM17186.1 - 1.1 9.5 6.6 1.9 8.6 4.6 1.4 1 0 0 1 1 1 0 Syntaxin DUF342 PF03961.8 GAM17186.1 - 4.3 5.6 6.9 6.8 4.9 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) HsbA PF12296.3 GAM17187.1 - 2.2 8.1 7.1 4.2 7.2 3.7 2.2 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Homeobox PF00046.24 GAM17188.1 - 2e-07 30.4 0.2 6.1e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAM17188.1 - 3.5e-07 29.8 0.0 8.1e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ribosomal_L7Ae PF01248.21 GAM17190.1 - 0.00014 21.3 0.0 0.00068 19.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Meiosis_expr PF15163.1 GAM17190.1 - 0.027 14.8 3.3 0.037 14.3 0.9 2.3 2 1 0 2 2 2 0 Meiosis-expressed AAA PF00004.24 GAM17191.1 - 1.5e-33 115.7 0.0 1.1e-32 112.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAM17191.1 - 2.3e-07 31.1 0.0 5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM17191.1 - 3e-07 30.6 0.0 7.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM17191.1 - 4.5e-07 29.4 0.3 0.012 15.0 0.0 2.7 2 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAM17191.1 - 3.8e-06 27.7 0.7 6.7e-06 26.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAM17191.1 - 6e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 GAM17191.1 - 2.5e-05 23.9 0.0 5.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 GAM17191.1 - 2.7e-05 24.0 0.0 7.4e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM17191.1 - 4.8e-05 23.4 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 1 1 RNA helicase UPF0079 PF02367.12 GAM17191.1 - 0.0001 21.9 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 GAM17191.1 - 0.00027 19.8 0.1 0.00038 19.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Arch_ATPase PF01637.13 GAM17191.1 - 0.00032 20.4 0.3 0.31 10.7 0.0 2.3 1 1 1 2 2 2 2 Archaeal ATPase AAA_24 PF13479.1 GAM17191.1 - 0.00035 20.2 0.0 0.00071 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAM17191.1 - 0.00056 19.5 0.0 0.0016 18.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 GAM17191.1 - 0.00097 18.7 0.0 0.0026 17.3 0.0 1.7 1 1 0 2 2 1 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 GAM17191.1 - 0.0014 17.7 0.7 0.28 10.1 0.0 2.5 2 1 1 3 3 2 1 KAP family P-loop domain AAA_33 PF13671.1 GAM17191.1 - 0.0015 18.3 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAM17191.1 - 0.0017 18.1 0.1 0.0044 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 GAM17191.1 - 0.0017 17.5 0.0 0.005 15.9 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 GAM17191.1 - 0.0017 17.9 0.1 0.0032 17.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAM17191.1 - 0.0018 18.2 0.0 0.0066 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAM17191.1 - 0.002 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 GAM17191.1 - 0.0025 16.8 0.0 0.0047 16.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 GAM17191.1 - 0.0026 17.7 0.0 0.0059 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAM17191.1 - 0.0035 17.6 0.0 0.0058 16.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PhoH PF02562.11 GAM17191.1 - 0.0038 16.4 0.0 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 GAM17191.1 - 0.006 15.5 0.1 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 GAM17191.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAM17191.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain DUF258 PF03193.11 GAM17191.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CPT PF07931.7 GAM17191.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 GAM17191.1 - 0.013 15.5 0.1 0.04 13.9 0.0 1.9 2 1 0 2 2 1 0 Sigma-54 interaction domain T2SE PF00437.15 GAM17191.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.4 GAM17191.1 - 0.027 13.9 0.1 0.071 12.5 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 GAM17191.1 - 0.028 13.3 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 GAM17191.1 - 0.034 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 GAM17191.1 - 0.041 13.0 0.0 0.092 11.8 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 GAM17191.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 GAM17191.1 - 0.047 14.0 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAM17191.1 - 0.056 12.6 0.1 0.45 9.6 0.0 2.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NMO PF03060.10 GAM17191.1 - 0.07 12.2 0.0 0.16 11.1 0.0 1.5 1 1 0 1 1 1 0 Nitronate monooxygenase KaiC PF06745.8 GAM17191.1 - 0.074 12.1 0.1 0.29 10.2 0.1 1.9 1 1 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 GAM17191.1 - 0.081 12.4 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 GAM17191.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain eIF-3c_N PF05470.7 GAM17192.1 - 4.3e-123 411.4 32.8 3e-121 405.4 19.6 3.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 GAM17192.1 - 1.6e-11 44.4 0.5 3.2e-10 40.2 0.0 3.0 3 0 0 3 3 3 1 PCI domain ERCC4 PF02732.10 GAM17193.1 - 2.3e-19 69.5 0.0 4.1e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain SWIM PF04434.12 GAM17193.1 - 0.0014 18.0 0.1 0.0028 17.0 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger SAM_2 PF07647.12 GAM17193.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Macoilin PF09726.4 GAM17193.1 - 0.33 9.1 9.0 0.47 8.6 6.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Oxysterol_BP PF01237.13 GAM17194.1 - 4e-89 298.5 0.0 5e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Git3 PF11710.3 GAM17195.1 - 0.03 13.8 0.7 0.046 13.2 0.5 1.2 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 SOBP PF15279.1 GAM17196.1 - 0.84 9.9 25.8 1.6 9.0 17.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein DnaJ PF00226.26 GAM17197.1 - 2.1e-14 52.9 1.0 5.7e-14 51.5 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4339 PF14237.1 GAM17197.1 - 8.2e-09 34.9 0.2 2.7e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) KTSC PF13619.1 GAM17197.1 - 0.049 13.2 1.4 26 4.5 0.0 3.5 3 0 0 3 3 3 0 KTSC domain FNIP PF05725.7 GAM17198.1 - 1.9e-77 254.9 30.8 4.9e-13 48.7 0.2 9.5 3 2 7 12 12 12 11 FNIP Repeat LRR_7 PF13504.1 GAM17198.1 - 0.037 14.1 3.9 59 4.5 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat DUF1769 PF08588.5 GAM17198.1 - 0.13 12.1 13.2 7.1 6.6 0.2 7.7 6 3 4 10 10 10 0 Protein of unknown function (DUF1769) CoaE PF01121.15 GAM17199.1 - 1.1e-46 158.4 0.2 1.4e-46 158.1 0.2 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 GAM17199.1 - 2.4e-06 28.3 1.3 5.8e-06 27.1 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM17199.1 - 5.2e-06 26.7 3.8 5.8e-05 23.4 2.3 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM17199.1 - 0.0043 16.9 0.2 0.047 13.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM17199.1 - 0.0046 16.9 1.0 0.026 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 GAM17199.1 - 0.01 15.7 0.9 0.02 14.7 0.6 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family MMR_HSR1 PF01926.18 GAM17199.1 - 0.022 14.7 0.1 0.054 13.4 0.0 1.8 1 1 1 2 2 2 0 50S ribosome-binding GTPase ATP_bind_2 PF03668.10 GAM17199.1 - 0.058 12.4 1.0 1.6 7.7 0.1 2.0 2 0 0 2 2 2 0 P-loop ATPase protein family FHA PF00498.21 GAM17200.1 - 3e-18 65.6 2.0 1.1e-17 63.9 0.4 2.5 2 0 0 2 2 2 1 FHA domain zf-RING_2 PF13639.1 GAM17200.1 - 1.4e-06 27.9 12.6 1.4e-06 27.9 8.7 4.2 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM17200.1 - 1e-05 25.4 13.7 1e-05 25.4 9.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM17200.1 - 2e-05 24.1 13.8 2e-05 24.1 9.6 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM17200.1 - 9.2e-05 22.0 12.9 9.2e-05 22.0 8.9 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM17200.1 - 0.00042 19.9 15.3 0.00042 19.9 10.6 4.0 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 GAM17200.1 - 0.0021 17.8 5.6 0.0021 17.8 3.9 3.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 GAM17200.1 - 0.0047 17.0 5.5 0.0047 17.0 3.8 4.2 4 1 0 4 4 4 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 GAM17200.1 - 0.0075 16.1 13.3 0.0075 16.1 9.2 3.3 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING SR-25 PF10500.4 GAM17201.1 - 0.00029 20.4 4.8 0.00029 20.4 3.4 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 GAM17201.1 - 0.00047 20.5 32.9 0.011 16.0 3.0 2.1 2 0 0 2 2 2 2 AAA domain Med15 PF09606.5 GAM17201.1 - 0.0032 15.7 12.7 0.0032 15.7 8.8 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 GAM17201.1 - 0.098 11.9 53.0 0.094 12.0 24.0 2.2 2 0 0 2 2 2 0 SprA-related family TFIIA PF03153.8 GAM17201.1 - 0.62 9.9 55.0 1 9.1 25.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop53 PF07767.6 GAM17201.1 - 1.3 7.9 33.3 0.095 11.6 12.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Ndc1_Nup PF09531.5 GAM17201.1 - 1.5 7.1 24.8 1 7.6 8.6 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CAF-1_p150 PF11600.3 GAM17201.1 - 1.6 8.0 39.3 0.22 10.8 11.8 3.1 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 GAM17201.1 - 2.6 6.2 38.3 0.016 13.5 6.2 2.1 2 0 0 2 2 2 0 Transmembrane protein Ribosomal_L18e PF00828.14 GAM17202.1 - 3.2e-17 63.1 0.9 4.8e-17 62.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_6 PF12697.2 GAM17203.1 - 3.3e-22 79.4 0.0 4.4e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM17203.1 - 1.8e-07 31.0 0.0 2.5e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM17203.1 - 0.0006 19.4 0.1 0.0032 17.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM17203.1 - 0.0015 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 GAM17203.1 - 0.0052 16.0 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Thioesterase PF00975.15 GAM17203.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain HA2 PF04408.18 GAM17204.1 - 2e-27 95.1 0.0 2e-27 95.1 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAM17204.1 - 2.4e-26 91.7 0.0 7.2e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAM17204.1 - 6.8e-10 38.6 0.0 1.8e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAM17204.1 - 7e-07 29.4 0.0 2.2e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 GAM17204.1 - 1.1e-06 28.2 0.1 3.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAM17204.1 - 0.0035 16.3 0.0 0.0069 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 GAM17204.1 - 0.0044 16.1 0.4 0.14 11.2 0.0 2.6 1 1 1 2 2 2 1 Zeta toxin SRP54 PF00448.17 GAM17204.1 - 0.0048 16.3 0.1 0.013 14.9 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.24 GAM17204.1 - 0.009 16.2 0.2 0.22 11.7 0.1 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAM17204.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 GAM17204.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain UPF0079 PF02367.12 GAM17204.1 - 0.03 13.9 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 GAM17204.1 - 0.032 14.5 3.0 0.1 12.9 0.2 2.9 2 1 0 2 2 1 0 ABC transporter T2SE PF00437.15 GAM17204.1 - 0.034 13.0 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 GAM17204.1 - 0.036 12.9 0.0 0.082 11.7 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 GAM17204.1 - 0.047 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 GAM17204.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 GAM17204.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 GAM17204.1 - 0.24 11.2 8.9 0.84 9.4 0.0 3.2 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF106 PF01956.11 GAM17205.1 - 7.7 6.0 7.1 0.76 9.2 1.3 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF106 Pkinase PF00069.20 GAM17206.1 - 1.6e-56 191.3 0.1 2.3e-56 190.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17206.1 - 1.4e-18 66.9 0.0 2.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM17206.1 - 5.9e-07 29.4 0.0 0.00017 21.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM17206.1 - 0.00034 19.6 0.0 0.00052 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM17206.1 - 0.043 12.8 0.2 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 GAM17207.1 - 6.8e-28 96.8 14.8 1.8e-08 34.5 0.9 5.3 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17207.1 - 1.4e-26 92.3 10.5 1.8e-05 25.0 0.1 7.6 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17207.1 - 9.1e-20 70.2 23.4 0.0012 19.0 0.3 10.5 1 1 10 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17207.1 - 1.7e-19 67.9 14.0 0.036 14.2 0.1 11.0 5 4 6 11 11 11 6 Ankyrin repeat Ank PF00023.25 GAM17207.1 - 4.5e-09 35.6 16.3 2 8.3 0.0 10.2 8 3 2 10 10 10 3 Ankyrin repeat DUF1450 PF07293.6 GAM17207.1 - 0.0022 17.9 8.7 3.5 7.6 0.0 5.0 3 2 2 5 5 5 3 Protein of unknown function (DUF1450) ENTH PF01417.15 GAM17207.1 - 0.019 14.8 1.3 20 5.0 0.0 4.6 4 1 0 5 5 5 0 ENTH domain DUF3322 PF11795.3 GAM17207.1 - 0.066 12.8 0.1 1.6 8.2 0.0 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) DUF1707 PF08044.6 GAM17207.1 - 0.37 10.5 5.2 19 5.0 0.1 4.6 4 1 1 5 5 5 0 Domain of unknown function (DUF1707) LBP_BPI_CETP PF01273.20 GAM17208.1 - 0.00036 19.9 0.1 0.00071 18.9 0.1 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Clathrin-link PF09268.5 GAM17208.1 - 0.029 13.4 0.1 0.075 12.0 0.1 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker His_Phos_1 PF00300.17 GAM17209.1 - 1.7e-23 83.4 0.0 2.2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pribosyltran PF00156.22 GAM17209.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Homeobox_KN PF05920.6 GAM17210.1 - 1.7e-17 62.7 0.2 4.4e-17 61.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAM17210.1 - 3.3e-08 33.0 0.3 7.5e-08 31.8 0.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 GAM17210.1 - 0.011 14.7 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez DUF3439 PF11921.3 GAM17210.1 - 0.11 12.2 3.5 0.11 12.2 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Menin PF05053.8 GAM17210.1 - 1.8 6.6 5.5 3.6 5.6 3.6 1.5 1 1 0 1 1 1 0 Menin Proteasome PF00227.21 GAM17211.1 - 2.8e-36 124.5 0.2 3.4e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ank_2 PF12796.2 GAM17212.1 - 5e-06 26.7 2.9 0.0022 18.3 0.0 4.0 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17212.1 - 0.00011 22.0 0.6 5.3 7.5 0.0 5.9 4 1 1 5 5 5 1 Ankyrin repeat Ank PF00023.25 GAM17212.1 - 0.001 18.7 3.5 4.6 7.2 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 GAM17212.1 - 0.015 15.7 3.6 0.11 13.0 0.3 4.0 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Tim44 PF04280.10 GAM17213.1 - 1.2e-12 48.0 0.0 4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain OmpH PF03938.9 GAM17213.1 - 0.42 10.5 9.7 0.73 9.7 6.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ubiquitin PF00240.18 GAM17214.1 - 1.3e-14 53.3 0.0 3.3e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM17214.1 - 1e-06 28.3 0.1 3.1e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAM17214.1 - 0.079 12.8 0.1 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF3439 PF11921.3 GAM17214.1 - 0.093 12.4 13.8 0.19 11.4 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM17214.1 - 0.18 11.5 23.7 0.8 9.4 16.4 2.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 GAM17214.1 - 0.3 8.7 9.0 0.61 7.7 6.2 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WD40 PF00400.27 GAM17215.1 - 1.5e-23 81.7 1.2 1.5e-08 34.2 0.1 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat UTP15_C PF09384.5 GAM17215.1 - 1.3e-22 80.0 3.2 2.3e-22 79.2 2.2 1.4 1 0 0 1 1 1 1 UTP15 C terminal Nup160 PF11715.3 GAM17215.1 - 0.00079 17.6 0.1 0.24 9.4 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Zip PF02535.17 GAM17215.1 - 3.4 6.5 6.3 6.1 5.7 4.4 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Ank_2 PF12796.2 GAM17217.1 - 2.7e-06 27.6 0.0 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17217.1 - 5.9e-06 26.6 0.0 0.13 12.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM17217.1 - 0.0013 18.4 2.6 0.0059 16.3 1.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3447) Ank PF00023.25 GAM17217.1 - 0.022 14.5 0.0 7.6 6.5 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat DUF2804 PF10974.3 GAM17217.1 - 0.065 12.0 0.2 0.088 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Ank_2 PF12796.2 GAM17218.1 - 2.3e-07 31.0 0.1 0.0011 19.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17218.1 - 6.2e-07 29.0 0.4 0.14 12.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAM17218.1 - 7.6e-06 26.0 0.3 0.41 10.9 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM17218.1 - 2.3e-05 23.9 0.4 0.78 9.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAM17218.1 - 0.0015 19.0 0.5 0.32 11.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3774 PF12609.3 GAM17218.1 - 8.1 7.3 15.6 9.5 7.1 1.4 2.8 2 1 0 2 2 2 0 Wound-induced protein Phage_CRI PF05144.9 GAM17219.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Phage replication protein CRI Beach PF02138.13 GAM17220.1 - 3.8e-110 367.5 0.0 3.8e-110 367.5 0.0 2.4 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM17220.1 - 9.2e-31 105.8 0.1 2.8e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 GAM17220.1 - 5.6e-16 59.1 1.1 1.8e-15 57.4 0.1 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 GAM17220.1 - 9.6e-16 56.9 9.6 3e-07 30.0 0.1 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Ank_4 PF13637.1 GAM17221.1 - 2.2e-38 129.9 7.3 1.4e-07 31.7 0.1 5.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM17221.1 - 2.6e-35 120.5 13.7 4.9e-14 52.4 1.2 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM17221.1 - 6.5e-33 110.8 9.9 3.1e-06 26.7 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 GAM17221.1 - 4.4e-25 87.1 9.1 9.2e-08 32.0 0.2 6.5 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17221.1 - 7.5e-25 84.5 13.1 0.00018 21.4 0.0 7.9 7 1 0 7 7 7 5 Ankyrin repeat SH2 PF00017.19 GAM17221.1 - 1.2e-08 34.6 0.0 3.7e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 SH2 domain F-box-like PF12937.2 GAM17221.1 - 1.1e-05 24.9 1.2 2.9e-05 23.7 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM17221.1 - 3.3e-05 23.4 0.6 8.8e-05 22.0 0.4 1.8 1 0 0 1 1 1 1 F-box domain SH2_2 PF14633.1 GAM17221.1 - 0.00097 18.2 0.0 0.0026 16.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Zip PF02535.17 GAM17221.1 - 0.81 8.6 6.1 0.6 9.0 2.9 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Folliculin PF11704.3 GAM17222.1 - 0.00066 19.3 2.1 0.00069 19.2 0.3 1.9 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Kelch_4 PF13418.1 GAM17223.1 - 5.4e-36 122.1 12.5 8.6e-08 31.8 0.4 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM17223.1 - 5.1e-28 96.5 26.5 3.6e-06 26.9 0.0 8.3 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM17223.1 - 2.4e-27 94.3 12.2 7.2e-07 29.0 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM17223.1 - 3e-27 93.6 26.8 2.6e-05 24.2 0.1 7.9 6 2 2 8 8 8 6 Kelch motif Kelch_1 PF01344.20 GAM17223.1 - 1.2e-26 91.9 22.9 5.4e-06 25.8 2.0 8.1 7 1 0 7 7 7 6 Kelch motif Kelch_2 PF07646.10 GAM17223.1 - 1.3e-21 75.4 10.3 4.8e-05 22.9 0.0 6.9 7 0 0 7 7 7 6 Kelch motif F-box PF00646.28 GAM17223.1 - 1.1e-07 31.3 0.2 2.3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM17223.1 - 1.3e-07 31.1 0.3 2.8e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like RAG2 PF03089.9 GAM17223.1 - 0.0066 15.2 0.1 0.15 10.7 0.0 3.0 2 1 2 4 4 4 1 Recombination activating protein 2 Rax2 PF12768.2 GAM17223.1 - 0.046 12.9 0.2 4.8 6.3 0.0 3.0 2 1 1 3 3 3 0 Cortical protein marker for cell polarity VWA_2 PF13519.1 GAM17224.1 - 1.1e-11 45.1 0.4 1e-10 42.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 GAM17224.1 - 7.8e-07 28.1 8.8 0.0011 18.2 2.0 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif Ssl1 PF04056.9 GAM17224.1 - 3.4e-06 26.8 1.0 1e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 Ssl1-like DUF1887 PF09002.6 GAM17224.1 - 0.0012 17.3 0.2 0.0021 16.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1887) UB2H PF14814.1 GAM17224.1 - 0.0013 18.4 0.1 0.0029 17.3 0.1 1.5 1 0 0 1 1 1 1 Bifunctional transglycosylase second domain SIR2_2 PF13289.1 GAM17224.1 - 0.07 13.0 0.4 0.49 10.2 0.1 2.3 2 0 0 2 2 2 0 SIR2-like domain Peptidase_M8 PF01457.11 GAM17225.1 - 5.5e-58 196.5 2.2 8.1e-58 196.0 1.5 1.1 1 0 0 1 1 1 1 Leishmanolysin DinB PF05163.7 GAM17226.1 - 0.085 12.5 0.6 0.097 12.3 0.4 1.0 1 0 0 1 1 1 0 DinB family Kelch_4 PF13418.1 GAM17228.1 - 5.3e-56 186.1 16.0 5.8e-12 45.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM17228.1 - 2.5e-36 123.0 13.7 2.4e-08 33.8 0.0 6.8 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM17228.1 - 3.3e-31 106.7 16.4 1.8e-06 27.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM17228.1 - 9.1e-28 95.2 15.0 2.3e-07 30.6 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 GAM17228.1 - 2.3e-22 78.2 20.4 1.1e-09 37.6 0.2 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAM17228.1 - 7.5e-19 66.6 17.3 0.00041 20.0 0.1 5.9 6 0 0 6 6 6 5 Kelch motif zf-C3HC4_3 PF13920.1 GAM17228.1 - 1.2e-06 28.1 7.0 2.2e-06 27.1 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.12 GAM17228.1 - 3.9e-06 26.5 5.1 3.9e-06 26.5 3.6 3.9 2 1 0 3 3 3 1 K-box region RAG2 PF03089.9 GAM17228.1 - 8.7e-06 24.6 0.1 0.15 10.7 0.0 2.9 2 1 0 2 2 2 2 Recombination activating protein 2 zf-C3HC4_2 PF13923.1 GAM17228.1 - 0.014 15.3 8.3 0.033 14.2 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RecA PF00154.16 GAM17229.1 - 1.2e-35 123.1 0.0 1.4e-33 116.3 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Rad51 PF08423.6 GAM17229.1 - 1.8e-09 36.9 0.1 1.6e-08 33.7 0.0 2.3 2 1 0 2 2 2 1 Rad51 AAA_25 PF13481.1 GAM17229.1 - 2.6e-07 30.2 0.0 5.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM17229.1 - 8.8e-07 28.2 0.0 2.7e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 GAM17229.1 - 0.0026 17.9 0.1 0.0091 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNase_H2_suC PF08615.6 GAM17229.1 - 0.026 14.3 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CobU PF02283.11 GAM17229.1 - 0.051 12.9 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CbiA PF01656.18 GAM17229.1 - 0.066 12.6 0.0 0.28 10.5 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4611 PF15387.1 GAM17229.1 - 0.2 11.8 4.5 0.4 10.8 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 GAM17229.1 - 1.1 9.5 7.0 2 8.7 4.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 GAM17229.1 - 1.7 8.1 5.1 3.1 7.2 3.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF2146 PF10220.4 GAM17231.1 - 2e-08 32.7 0.5 2e-08 32.7 0.3 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2146) DUF1777 PF08648.7 GAM17231.1 - 3.6e-08 33.3 29.1 7.8e-08 32.2 20.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Dynamin_N PF00350.18 GAM17231.1 - 0.0028 17.4 0.2 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family CDK5_activator PF03261.10 GAM17231.1 - 0.008 15.5 3.4 0.014 14.7 2.3 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein Miro PF08477.8 GAM17231.1 - 0.0081 16.6 0.1 0.039 14.4 0.1 2.2 1 1 0 1 1 1 1 Miro-like protein MIP-T3 PF10243.4 GAM17231.1 - 0.0086 14.5 10.1 0.012 14.0 7.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 MMR_HSR1 PF01926.18 GAM17231.1 - 0.009 15.9 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.20 GAM17232.1 - 1.9e-53 181.2 0.1 1.9e-53 181.2 0.1 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17232.1 - 4e-21 75.2 0.0 4e-21 75.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 GAM17232.1 - 0.012 14.9 0.3 0.012 14.9 0.2 2.5 2 1 1 3 3 3 0 RIO1 family APH PF01636.18 GAM17232.1 - 0.018 14.7 1.2 0.043 13.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_3 PF13606.1 GAM17233.1 - 1.8e-10 40.0 5.9 0.16 12.3 0.0 7.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_2 PF12796.2 GAM17233.1 - 2e-09 37.6 1.8 0.008 16.4 0.3 5.3 2 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM17233.1 - 6.4e-09 35.7 1.7 0.84 9.9 0.0 7.0 7 1 1 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM17233.1 - 1.5e-05 25.3 1.8 15 6.2 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM17233.1 - 0.0028 17.3 5.5 3.9 7.4 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat BolA PF01722.13 GAM17233.1 - 0.031 14.2 1.3 0.075 12.9 0.9 1.6 1 0 0 1 1 1 0 BolA-like protein Ank_2 PF12796.2 GAM17234.1 - 0.0066 16.7 0.0 0.018 15.3 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM17234.1 - 0.0081 16.3 0.8 1.4 9.2 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM17234.1 - 0.078 13.5 0.4 17 6.0 0.0 2.4 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DUF1322 PF07032.6 GAM17234.1 - 0.13 12.4 0.6 0.23 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) DUF3447 PF11929.3 GAM17234.1 - 0.35 10.6 3.2 6.3 6.6 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) zf-C3HC4_2 PF13923.1 GAM17235.1 - 0.0045 16.9 2.7 0.0089 16.0 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF948 PF06103.6 GAM17235.1 - 0.0048 16.7 2.8 0.0048 16.7 2.0 5.7 5 1 2 7 7 7 1 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.8 GAM17235.1 - 0.0052 15.7 18.9 0.0052 15.7 13.1 6.2 2 1 3 5 5 5 2 HAP1 N-terminal conserved region zf-C3HC4_3 PF13920.1 GAM17235.1 - 0.0081 15.8 2.2 0.015 14.9 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM17235.1 - 0.024 14.3 3.3 0.064 12.9 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM17235.1 - 0.087 12.5 1.7 0.29 10.8 1.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 GAM17235.1 - 0.094 12.5 0.6 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 GAM17235.1 - 0.25 11.1 3.1 0.52 10.0 2.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain SUI1 PF01253.17 GAM17236.1 - 1.8e-26 91.7 1.5 2.5e-26 91.3 1.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.9 GAM17236.1 - 0.027 14.6 0.4 0.047 13.9 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) RhoGAP PF00620.22 GAM17237.1 - 8.3e-34 116.3 0.4 2e-33 115.1 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain Choline_transpo PF04515.7 GAM17238.1 - 1.3e-41 142.4 17.3 1e-40 139.5 12.0 1.9 1 1 0 1 1 1 1 Plasma-membrane choline transporter PhaG_MnhG_YufB PF03334.9 GAM17238.1 - 0.09 12.8 5.8 0.79 9.8 3.2 2.5 2 0 0 2 2 2 0 Na+/H+ antiporter subunit FUSC_2 PF13515.1 GAM17238.1 - 0.19 11.6 15.9 0.22 11.4 1.8 3.3 3 0 0 3 3 3 0 Fusaric acid resistance protein-like DUF2417 PF10329.4 GAM17238.1 - 0.29 10.5 4.6 0.13 11.6 1.1 1.9 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF3671 PF12420.3 GAM17238.1 - 2.6 8.0 9.5 0.81 9.6 0.9 3.4 3 1 0 3 3 3 0 Protein of unknown function Aa_trans PF01490.13 GAM17239.1 - 4e-49 167.2 20.3 4.6e-49 167.0 14.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 GAM17239.1 - 1.7e-06 27.1 2.7 1.7e-06 27.1 1.9 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family EF-hand_7 PF13499.1 GAM17240.1 - 2.8e-12 46.5 0.0 1.8e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM17240.1 - 3.2e-11 41.6 0.0 0.0012 17.9 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 GAM17240.1 - 7.9e-09 34.4 0.0 0.016 14.5 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAM17240.1 - 1.3e-08 33.9 0.0 0.28 11.1 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM17240.1 - 4.5e-06 26.1 0.0 0.001 18.6 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair Ribosomal_L12 PF00542.14 GAM17241.1 - 2.5e-18 65.8 6.1 2.5e-18 65.8 4.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain SpoVIF PF14069.1 GAM17241.1 - 0.061 13.0 2.4 0.2 11.4 0.2 2.2 2 0 0 2 2 2 0 Stage VI sporulation protein F Aldedh PF00171.17 GAM17242.1 - 5.5e-169 562.3 0.0 6.1e-169 562.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM17242.1 - 0.006 15.3 0.0 0.0099 14.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ras PF00071.17 GAM17243.1 - 2.1e-10 40.2 0.0 5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17243.1 - 0.00042 20.7 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein CCG PF02754.11 GAM17243.1 - 0.072 13.0 0.2 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Cysteine-rich domain Ank_4 PF13637.1 GAM17243.1 - 0.1 13.1 0.1 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) WAP PF00095.16 GAM17244.1 - 3.1e-09 36.6 55.2 0.0016 18.3 8.1 3.1 3 0 0 3 3 3 3 WAP-type (Whey Acidic Protein) 'four-disulfide core' Defensin_propep PF00879.13 GAM17244.1 - 0.1 12.5 0.3 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 Defensin propeptide Pkinase PF00069.20 GAM17248.1 - 5.1e-23 81.5 0.2 9.8e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17248.1 - 1e-20 73.9 0.0 1.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.7 GAM17248.1 - 7.9e-07 29.5 7.5 0.66 10.6 0.0 7.3 9 0 0 9 9 9 3 Sel1 repeat Kdo PF06293.9 GAM17248.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FA_hydroxylase PF04116.8 GAM17249.1 - 1.8e-13 50.8 15.9 1.8e-13 50.8 11.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PepSY_TM_2 PF13703.1 GAM17249.1 - 2.8 8.1 8.3 0.41 10.8 0.2 2.7 3 0 0 3 3 3 0 PepSY-associated TM helix RhoGEF PF00621.15 GAM17250.1 - 9e-49 165.7 0.4 9e-49 165.7 0.3 2.0 3 0 0 3 3 3 1 RhoGEF domain AAA_23 PF13476.1 GAM17250.1 - 0.0051 17.1 0.1 0.0051 17.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain DNA_pol_B_2 PF03175.8 GAM17251.1 - 0.002 16.8 0.0 0.002 16.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral FNIP PF05725.7 GAM17253.1 - 2.8e-65 216.0 20.7 3.1e-12 46.2 0.1 10.4 6 1 1 10 10 10 9 FNIP Repeat NIP_1 PF08995.5 GAM17253.1 - 0.93 9.7 3.3 3.7 7.7 0.1 3.7 4 1 0 4 4 4 0 Necrosis inducing protein-1 Coiled PF05710.7 GAM17254.1 - 0.00071 19.9 9.8 0.00098 19.5 6.8 1.2 1 0 0 1 1 1 1 Coiled coil SDH_alpha PF03313.10 GAM17254.1 - 0.6 9.0 3.4 0.72 8.8 2.4 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Coiled PF05710.7 GAM17255.1 - 0.00063 20.1 9.4 0.00085 19.7 6.5 1.2 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.7 GAM17256.1 - 0.00071 19.9 9.8 0.00098 19.5 6.8 1.2 1 0 0 1 1 1 1 Coiled coil SDH_alpha PF03313.10 GAM17256.1 - 0.6 9.0 3.4 0.72 8.8 2.4 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain WD40 PF00400.27 GAM17257.1 - 1.7e-45 151.3 16.6 6.7e-10 38.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 GAM17257.1 - 4.6e-19 68.1 0.1 8.2e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Cob_adeno_trans PF01923.13 GAM17258.1 - 2.4e-53 180.2 0.0 3.7e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase AKNA PF12443.3 GAM17258.1 - 0.0064 16.5 0.1 0.67 10.0 0.0 2.8 1 1 1 2 2 2 2 AT-hook-containing transcription factor SAP PF02037.22 GAM17260.1 - 1.1e-05 24.7 0.1 1.1e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 SAP domain Carboxyl_trans PF01039.17 GAM17261.1 - 2.8e-161 537.2 0.1 3.3e-161 536.9 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 GAM17261.1 - 0.0057 15.8 0.1 1.4 8.0 0.0 2.5 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) ECH PF00378.15 GAM17261.1 - 0.69 8.9 2.7 4.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family RCC1 PF00415.13 GAM17263.1 - 1.4e-62 207.6 10.5 6.3e-14 51.9 0.0 8.6 7 3 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM17263.1 - 3.5e-35 118.8 53.5 2.7e-09 36.4 0.3 8.4 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.1 GAM17263.1 - 0.011 15.9 5.0 0.58 10.4 0.1 4.6 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 GAM17263.1 - 0.042 13.3 0.3 0.28 10.7 0.0 2.6 3 0 0 3 3 3 0 Kelch motif SUKH-3 PF14433.1 GAM17263.1 - 0.2 11.4 0.9 0.73 9.6 0.0 2.4 3 0 0 3 3 3 0 SUKH-3 immunity protein NAGLU PF05089.7 GAM17264.1 - 4.2e-133 443.2 6.5 4.2e-133 443.2 4.5 1.5 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAM17264.1 - 1.2e-62 211.7 3.8 1.8e-62 211.1 2.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAM17264.1 - 1.2e-17 63.3 0.0 2.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Oxidored_molyb PF00174.14 GAM17265.1 - 2.8e-52 176.5 0.0 3.9e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 GAM17265.1 - 5.4e-36 123.1 0.1 1.5e-35 121.7 0.0 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 GAM17265.1 - 0.017 14.8 0.7 0.23 11.4 0.1 3.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Cas6 PF09559.5 GAM17265.1 - 0.13 11.9 0.0 14 5.3 0.0 2.1 2 0 0 2 2 2 0 Cas6 Crispr CLU PF13236.1 GAM17266.1 - 4.2e-48 163.6 0.0 1.5e-47 161.9 0.0 2.0 2 0 0 2 2 2 1 Clustered mitochondria SH2 PF00017.19 GAM17266.1 - 1.3e-09 37.7 0.0 4.5e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 SH2 domain eIF3_p135 PF12807.2 GAM17266.1 - 5e-08 33.0 10.0 7.1e-08 32.5 4.5 3.0 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.1 GAM17266.1 - 0.00082 18.9 1.0 0.23 11.1 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 GAM17266.1 - 0.038 14.3 2.7 3.6 7.9 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RGS PF00615.14 GAM17267.1 - 4.7e-24 84.7 0.7 1.2e-23 83.3 0.5 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF4167 PF13763.1 GAM17267.1 - 0.22 11.5 4.2 0.39 10.7 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) dNK PF01712.14 GAM17268.1 - 5.5e-21 75.0 0.4 1.3e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.1 GAM17268.1 - 1.7e-05 24.8 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 GAM17268.1 - 0.00016 21.2 0.1 0.00036 20.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Thymidylate_kin PF02223.12 GAM17268.1 - 0.00019 20.8 0.0 0.00052 19.4 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 GAM17268.1 - 0.0031 18.3 0.0 0.0047 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM17268.1 - 0.0067 16.3 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM17268.1 - 0.036 13.9 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAM17268.1 - 0.073 13.3 0.0 0.5 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.2 GAM17270.1 - 1.3e-07 31.8 0.0 0.14 12.4 0.0 4.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17270.1 - 0.00011 22.0 0.1 0.86 10.0 0.0 5.8 7 0 0 7 7 7 1 Ankyrin repeat DUF3447 PF11929.3 GAM17270.1 - 0.0079 15.9 6.1 0.03 14.1 0.0 4.6 5 1 1 6 6 6 1 Domain of unknown function (DUF3447) His_Phos_1 PF00300.17 GAM17271.1 - 4e-32 111.5 0.2 6.3e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RNA_pol_Rpb2_4 PF04566.8 GAM17271.1 - 0.16 11.8 1.0 0.41 10.4 0.1 2.2 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 Picorna_P3A PF06363.6 GAM17272.1 - 0.026 14.5 1.4 0.14 12.1 0.6 2.4 2 0 0 2 2 2 0 Picornaviridae P3A protein RhoGAP PF00620.22 GAM17273.1 - 2.1e-30 105.3 0.0 3.1e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain ATG_C PF09333.6 GAM17273.1 - 7.8e-08 32.3 0.2 1.7e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 ATG C terminal domain SBF PF01758.11 GAM17274.1 - 1.7e-44 151.4 14.0 1.7e-44 151.4 9.7 2.2 1 1 1 2 2 2 1 Sodium Bile acid symporter family LMWPc PF01451.16 GAM17274.1 - 3.1e-23 82.6 0.1 6.2e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PfkB PF00294.19 GAM17276.1 - 8.7e-05 21.7 0.5 0.0002 20.6 0.1 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase p450 PF00067.17 GAM17277.1 - 6.6e-75 252.3 0.8 2e-61 207.9 0.1 2.0 1 1 1 2 2 2 2 Cytochrome P450 PARP PF00644.15 GAM17278.1 - 5.9e-17 61.7 0.2 4.4e-15 55.6 0.2 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.21 GAM17278.1 - 1.6e-13 50.6 0.0 5.4e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WWE PF02825.15 GAM17278.1 - 7.5e-13 47.7 4.1 3.8e-07 29.4 0.1 3.5 3 0 0 3 3 3 2 WWE domain zf-CCHH PF10283.4 GAM17278.1 - 1.3e-11 44.1 1.8 2.9e-11 42.9 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif PTCB-BRCT PF12738.2 GAM17278.1 - 8.5e-08 31.9 1.5 2.4e-07 30.4 1.1 1.9 1 0 0 1 1 1 1 twin BRCT domain WD40 PF00400.27 GAM17279.1 - 1.2e-16 59.9 2.5 9e-08 31.7 0.1 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Dscam_C PF12355.3 GAM17279.1 - 0.06 13.6 0.5 0.14 12.4 0.4 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Notch PF00066.12 GAM17280.1 - 2.2e-18 66.2 35.4 1.6e-09 37.8 11.4 2.4 2 0 0 2 2 2 2 LNR domain DUF3184 PF11380.3 GAM17280.1 - 1e-05 23.7 9.3 7.2e-05 20.9 0.1 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF3184) DUF4083 PF13314.1 GAM17280.1 - 0.0043 16.8 1.2 0.012 15.3 0.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) FNIP PF05725.7 GAM17281.1 - 3.7e-86 282.8 42.7 9.7e-13 47.8 0.0 12.3 9 4 4 13 13 13 10 FNIP Repeat DUF1769 PF08588.5 GAM17281.1 - 0.00066 19.5 20.2 7.4 6.5 0.1 9.3 6 3 7 13 13 13 3 Protein of unknown function (DUF1769) F-box PF00646.28 GAM17281.1 - 0.0069 16.0 0.2 0.023 14.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain RRM_1 PF00076.17 GAM17282.1 - 1.4e-29 101.4 4.4 9.1e-22 76.4 0.2 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17282.1 - 4.9e-23 80.8 0.2 6.7e-15 54.8 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17282.1 - 1.4e-11 44.0 0.5 2.5e-09 36.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IF4E PF01652.13 GAM17283.1 - 1.1e-48 164.9 0.2 1.4e-48 164.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E eIF3g PF12353.3 GAM17284.1 - 1.8e-22 79.6 9.1 6.1e-22 77.9 6.3 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 GAM17284.1 - 7.4e-20 70.3 0.0 1.7e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17284.1 - 8.3e-15 54.5 0.1 5.6e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17284.1 - 6.9e-12 45.0 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM17284.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EF-hand_1 PF00036.27 GAM17285.1 - 2.4e-40 132.7 12.1 1.4e-09 36.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM17285.1 - 1.3e-38 130.8 3.7 4.5e-21 74.7 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM17285.1 - 2.6e-33 113.3 11.6 4.2e-16 58.2 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 GAM17285.1 - 9e-31 102.9 4.8 3.1e-09 35.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAM17285.1 - 2.4e-26 89.8 7.2 4.2e-07 29.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAM17285.1 - 1.8e-13 50.1 0.1 1.5e-07 31.2 0.0 2.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 GAM17285.1 - 7e-09 35.3 1.1 0.0002 21.0 0.1 2.4 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAM17285.1 - 9.8e-09 35.2 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 GAM17285.1 - 1.9e-05 24.1 1.7 0.32 10.6 0.0 3.5 4 1 1 5 5 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 GAM17285.1 - 3.6e-05 23.6 0.9 0.00032 20.6 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 GAM17285.1 - 0.00019 20.9 2.7 0.00023 20.6 1.9 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EF-hand_like PF09279.6 GAM17285.1 - 0.00082 19.3 1.1 0.01 15.8 0.1 2.5 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like Caleosin PF05042.8 GAM17285.1 - 0.0014 18.1 0.2 0.043 13.3 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 GAM17285.1 - 0.0045 16.9 2.5 0.64 10.0 0.1 2.9 4 0 0 4 4 3 1 RNA polymerase Rpb4 SapB_1 PF05184.10 GAM17285.1 - 0.016 15.0 1.3 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 TerB PF05099.8 GAM17285.1 - 0.02 14.5 0.2 1.6 8.4 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Acetyltransf_11 PF13720.1 GAM17285.1 - 0.023 14.9 0.1 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Toprim_2 PF13155.1 GAM17285.1 - 0.031 14.5 0.7 3.6 7.9 0.0 2.4 1 1 1 2 2 2 0 Toprim-like MotA_activ PF09114.5 GAM17285.1 - 0.041 13.6 0.2 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Tenui_NCP PF04876.7 GAM17285.1 - 0.043 13.3 0.2 0.32 10.5 0.1 2.2 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein DUF4576 PF15144.1 GAM17285.1 - 0.058 13.0 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) KIP1 PF07765.7 GAM17285.1 - 0.6 9.9 2.6 10 6.0 0.0 3.3 3 1 1 4 4 4 0 KIP1-like protein WD40 PF00400.27 GAM17286.1 - 3.9e-55 181.8 20.6 3.5e-09 36.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM17286.1 - 4.4e-06 25.1 12.1 0.021 12.9 0.1 5.4 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM17286.1 - 0.00072 18.4 1.4 1.7 7.3 0.0 4.1 1 1 1 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 GAM17286.1 - 0.00084 18.8 3.4 1 8.7 0.1 3.3 2 2 1 3 3 3 3 PQQ-like domain Alpha_L_fucos PF01120.12 GAM17287.1 - 1.2e-114 382.8 8.1 1.5e-114 382.5 5.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GTP_EFTU PF00009.22 GAM17288.1 - 4.9e-47 159.7 0.0 8.2e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 GAM17288.1 - 3.2e-44 149.2 1.3 6.9e-44 148.1 0.9 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 GAM17288.1 - 1.9e-16 59.6 0.0 4.5e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM17288.1 - 2.7e-06 27.3 0.6 6.7e-06 26.1 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 GAM17288.1 - 0.00024 20.6 0.3 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 GAM17288.1 - 0.0022 17.9 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM17288.1 - 0.0051 16.0 0.1 0.099 11.8 0.1 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM17288.1 - 0.0083 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 GAM17288.1 - 0.094 12.5 0.1 0.51 10.2 0.1 2.2 1 1 0 1 1 1 0 Elongation Factor G, domain II ACC_central PF08326.7 GAM17289.1 - 0.075 11.1 0.2 0.086 10.9 0.1 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region Ras PF00071.17 GAM17290.1 - 4.5e-57 191.9 0.9 5.3e-57 191.7 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17290.1 - 2e-21 76.6 0.2 2.7e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17290.1 - 7.1e-14 51.4 0.4 7.9e-14 51.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM17290.1 - 6e-07 29.0 0.2 1.3e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM17290.1 - 2.6e-05 24.1 0.2 3.9e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM17290.1 - 6.5e-05 22.1 0.3 6.9e-05 22.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM17290.1 - 7.6e-05 21.9 0.1 0.00011 21.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAM17290.1 - 0.0021 17.3 0.1 0.032 13.4 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 GAM17290.1 - 0.0062 16.0 0.3 0.034 13.6 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 GAM17290.1 - 0.054 12.6 0.1 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF791 PF05631.9 GAM17291.1 - 1e-99 333.6 16.7 1.7e-99 332.9 11.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 GAM17291.1 - 1.9e-18 66.3 54.3 9.2e-18 64.0 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3681 PF12442.3 GAM17291.1 - 0.024 14.8 0.4 0.069 13.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3681) GHL12 PF14882.1 GAM17292.1 - 0.13 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 Lambda_CIII PF02061.11 GAM17292.1 - 0.13 12.2 0.7 9.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Lambda Phage CIII BTB PF00651.26 GAM17293.1 - 2.8e-21 75.6 0.6 6.8e-20 71.1 0.1 2.8 2 1 1 3 3 3 1 BTB/POZ domain F5_F8_type_C PF00754.20 GAM17293.1 - 4.8e-07 29.6 0.5 4.8e-07 29.6 0.3 2.0 3 0 0 3 3 3 1 F5/8 type C domain BACK PF07707.10 GAM17293.1 - 0.00013 21.7 1.0 0.14 12.0 0.0 4.1 4 0 0 4 4 4 1 BTB And C-terminal Kelch DUF3342 PF11822.3 GAM17293.1 - 0.00027 20.1 1.0 0.0022 17.2 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) BTB_2 PF02214.17 GAM17293.1 - 0.0094 16.1 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain D123 PF07065.9 GAM17294.1 - 1.6e-86 290.1 6.4 5.4e-77 258.8 2.4 2.0 1 1 1 2 2 2 2 D123 DUF4343 PF14243.1 GAM17294.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) NFRKB_winged PF14465.1 GAM17295.1 - 4.8 7.0 8.3 0.28 11.0 0.8 2.7 3 1 0 3 3 3 0 NFRKB Winged Helix-like Snf7 PF03357.16 GAM17296.1 - 3.7e-41 140.3 15.9 4.6e-41 140.0 11.0 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin PF02996.12 GAM17296.1 - 0.0094 15.5 9.6 0.056 13.0 0.0 3.3 2 1 2 4 4 4 1 Prefoldin subunit DUF4140 PF13600.1 GAM17296.1 - 0.016 15.6 2.9 0.14 12.6 0.0 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Glutaredoxin PF00462.19 GAM17296.1 - 0.13 12.2 0.4 0.36 10.8 0.1 1.8 1 1 0 1 1 1 0 Glutaredoxin OmpH PF03938.9 GAM17296.1 - 0.17 11.8 19.9 0.027 14.3 5.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Pup PF05639.6 GAM17296.1 - 0.41 11.1 4.0 1.2 9.6 2.8 1.9 1 1 0 1 1 1 0 Pup-like protein DUF342 PF03961.8 GAM17296.1 - 1.5 7.1 12.3 0.16 10.3 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4094 PF13334.1 GAM17296.1 - 1.9 8.9 6.2 7.7 6.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) TBPIP PF07106.8 GAM17296.1 - 2.2 7.7 16.7 5.3 6.5 3.3 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 GAM17296.1 - 2.6 7.0 14.4 1.2 8.0 7.9 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 YlqD PF11068.3 GAM17296.1 - 3.3 7.7 13.4 1.9 8.5 7.4 1.9 1 1 1 2 2 2 0 YlqD protein PALP PF00291.20 GAM17297.1 - 4.6e-66 223.1 0.5 5.5e-66 222.8 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1186 PF06685.6 GAM17297.1 - 0.091 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) TPR_1 PF00515.23 GAM17299.1 - 3.3e-26 89.7 22.5 9.4e-05 21.8 0.3 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM17299.1 - 6.9e-19 66.1 28.7 0.0066 16.2 0.1 8.3 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 GAM17299.1 - 7.4e-19 67.1 25.4 9.8e-09 34.7 0.4 6.3 3 1 3 6 6 6 4 TPR repeat APC8 PF04049.8 GAM17299.1 - 1.3e-17 63.8 4.4 8.7e-17 61.1 0.2 2.7 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_12 PF13424.1 GAM17299.1 - 5.1e-15 55.1 22.5 2.8e-06 27.1 0.4 5.6 2 1 4 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAM17299.1 - 2.1e-14 52.1 17.8 0.00052 19.6 0.0 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM17299.1 - 3.4e-13 48.9 19.2 0.0018 18.7 0.0 8.7 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM17299.1 - 3.3e-12 46.7 25.3 5.6e-07 30.0 0.1 7.1 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM17299.1 - 2.4e-09 36.3 18.7 0.00049 19.7 0.6 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM17299.1 - 1.2e-07 31.7 23.8 0.0012 18.9 0.0 5.4 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 zf-B_box PF00643.19 GAM17299.1 - 2.8e-07 30.3 7.5 6.4e-07 29.1 5.2 1.7 1 0 0 1 1 1 1 B-box zinc finger TPR_17 PF13431.1 GAM17299.1 - 1.1e-05 25.1 16.7 0.0068 16.5 0.0 7.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM17299.1 - 0.0005 19.8 11.1 0.3 11.0 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.5 GAM17299.1 - 0.0032 16.2 0.3 0.3 9.8 0.0 2.9 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 GAM17299.1 - 0.011 15.6 5.1 0.64 9.9 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 GAM17299.1 - 0.023 14.4 2.3 0.023 14.4 1.6 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17299.1 - 0.24 11.7 0.1 0.086 13.1 2.9 6.5 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM17299.1 - 0.63 10.6 24.9 6.4 7.4 1.1 9.2 9 1 0 9 9 9 0 Tetratricopeptide repeat Kinesin PF00225.18 GAM17301.1 - 1.3e-110 369.2 1.2 3.6e-110 367.8 0.8 1.8 1 0 0 1 1 1 1 Kinesin motor domain F-box-like PF12937.2 GAM17302.1 - 1.8e-09 37.1 0.1 4.5e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM17302.1 - 2.6e-06 26.9 0.0 6.7e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 GAM17302.1 - 0.017 14.9 0.0 0.017 14.9 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat PBP1_TM PF14812.1 GAM17302.1 - 1.9 8.8 15.0 2.2 8.6 1.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 GAM17302.1 - 8.4 5.8 12.3 6.9 6.1 2.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin ELMO_CED12 PF04727.8 GAM17303.1 - 1.9e-40 138.1 0.5 3.7e-40 137.2 0.3 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family Ank PF00023.25 GAM17303.1 - 4.7e-30 101.8 2.6 1.1e-08 34.3 0.0 6.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 GAM17303.1 - 2.2e-27 95.2 3.8 1.5e-19 70.1 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17303.1 - 4.1e-22 76.0 2.9 8.6e-06 25.5 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 GAM17303.1 - 4.7e-22 77.9 1.8 6e-13 48.9 0.0 5.3 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17303.1 - 2.2e-18 65.8 6.6 4.6e-10 39.4 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TRM13 PF05206.9 GAM17304.1 - 0.046 12.9 0.0 0.29 10.3 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase TRM13 RE_EcoO109I PF14511.1 GAM17305.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I EB PF01683.13 GAM17305.1 - 0.83 9.7 78.3 0.053 13.5 1.7 8.5 2 2 6 8 8 8 0 EB module UCH PF00443.24 GAM17306.1 - 4e-45 154.0 1.8 4e-45 154.0 1.2 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM17306.1 - 7.8e-20 71.4 2.7 1.3e-14 54.3 0.5 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAM17306.1 - 5.8e-15 55.4 13.2 2.7e-09 37.3 0.0 5.2 4 1 0 4 4 4 3 DUSP domain ubiquitin PF00240.18 GAM17306.1 - 0.0013 18.0 0.1 0.0075 15.6 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family DUF4110 PF13422.1 GAM17306.1 - 0.067 13.0 2.9 0.2 11.5 2.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) GFA PF04828.9 GAM17306.1 - 0.41 10.6 9.5 0.2 11.6 0.4 3.1 4 0 0 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme FNIP PF05725.7 GAM17307.1 - 2.7e-47 158.4 8.2 9.6e-12 44.6 0.0 4.7 2 1 3 5 5 5 5 FNIP Repeat LRR_8 PF13855.1 GAM17307.1 - 0.019 14.7 8.1 1.2 8.8 0.1 4.4 3 2 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 GAM17307.1 - 0.52 10.5 2.8 32 5.0 0.0 4.2 3 1 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 GAM17307.1 - 2.7 8.5 5.0 12 6.6 0.0 4.3 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 GAM17307.1 - 3.4 8.0 5.7 95 3.6 0.0 4.6 3 1 0 3 3 3 0 Leucine Rich Repeat WWE PF02825.15 GAM17308.1 - 0.0013 18.1 0.6 0.0028 17.0 0.4 1.6 1 0 0 1 1 1 1 WWE domain BRCT PF00533.21 GAM17308.1 - 0.0098 16.0 0.1 0.029 14.5 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain G-alpha PF00503.15 GAM17309.1 - 1.7e-126 422.0 1.5 2e-126 421.7 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM17309.1 - 4.8e-15 55.2 0.3 2.6e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM17309.1 - 0.00018 20.7 0.3 0.09 11.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM17309.1 - 0.0011 19.4 0.2 0.16 12.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 GAM17309.1 - 0.0016 18.3 0.2 0.066 13.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM17309.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain VID27 PF08553.5 GAM17310.1 - 2.2e-124 416.5 28.8 2.4e-92 310.5 9.2 3.1 1 1 2 3 3 3 2 VID27 cytoplasmic protein C_GCAxxG_C_C PF09719.5 GAM17310.1 - 0.21 11.3 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) GRP PF07172.6 GAM17312.1 - 0.025 15.0 0.5 0.025 15.0 0.3 2.7 3 0 0 3 3 3 0 Glycine rich protein family SPC22 PF04573.7 GAM17313.1 - 2.1e-39 134.5 1.1 2.6e-39 134.2 0.8 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Ras PF00071.17 GAM17314.1 - 5.9e-45 152.5 0.0 7.1e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17314.1 - 3.4e-16 59.8 0.0 5.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17314.1 - 6.4e-06 25.5 0.0 1e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM17314.1 - 0.018 14.2 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM17314.1 - 0.13 11.7 0.2 0.53 9.6 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RUN PF02759.14 GAM17315.1 - 1.9e-20 72.9 0.4 1.9e-20 72.9 0.3 3.2 3 1 0 3 3 3 1 RUN domain PH PF00169.24 GAM17315.1 - 0.051 13.7 3.4 0.097 12.8 0.0 3.1 4 0 0 4 4 4 0 PH domain APG6 PF04111.7 GAM17315.1 - 7 5.6 26.0 0.15 11.0 7.4 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 RhoGAP PF00620.22 GAM17316.1 - 1.1e-27 96.5 0.1 3.3e-27 94.9 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAM17316.1 - 4.1e-15 55.7 0.2 4.1e-15 55.7 0.1 3.2 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain Mpp10 PF04006.7 GAM17318.1 - 2.3e-92 310.2 101.3 3.9e-92 309.5 70.2 1.3 1 0 0 1 1 1 1 Mpp10 protein ADK PF00406.17 GAM17319.1 - 1.8e-09 37.6 0.6 9.9e-09 35.2 0.2 2.5 1 1 1 2 2 2 1 Adenylate kinase DUF1735 PF08522.5 GAM17320.1 - 5.3 7.5 9.3 2.8 8.3 0.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1735) PLA2G12 PF06951.6 GAM17321.1 - 0.051 13.2 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) TMEM154 PF15102.1 GAM17323.1 - 0.15 11.7 5.6 0.55 9.9 3.8 2.0 1 0 0 1 1 1 0 TMEM154 protein family RWD PF05773.17 GAM17324.1 - 6.6e-18 64.6 0.0 1.8e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 GAM17324.1 - 2.5e-15 56.0 47.9 5e-06 26.3 7.3 4.2 3 1 1 4 4 4 4 IBR domain DUF1451 PF07295.6 GAM17324.1 - 0.035 13.8 8.3 0.64 9.7 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Pkinase PF00069.20 GAM17325.1 - 6.1e-87 291.0 0.3 2.3e-44 151.4 0.0 4.0 3 2 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17325.1 - 9.2e-46 156.0 0.2 2.5e-15 56.2 0.1 4.3 4 0 0 4 4 4 4 Protein tyrosine kinase tRNA-synt_His PF13393.1 GAM17325.1 - 3.6e-18 65.6 0.0 6.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 GAM17325.1 - 2.6e-15 56.3 0.6 2.6e-15 56.3 0.4 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.17 GAM17325.1 - 1.1e-14 54.2 0.8 4.4e-14 52.3 0.6 2.2 1 0 0 1 1 1 1 RWD domain HGTP_anticodon PF03129.15 GAM17325.1 - 8.1e-07 28.8 0.1 2.2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Kinase-like PF14531.1 GAM17325.1 - 9.8e-06 24.7 0.4 0.054 12.4 0.0 4.3 4 0 0 4 4 4 1 Kinase-like APH PF01636.18 GAM17325.1 - 0.00038 20.2 0.1 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Serglycin PF04360.7 GAM17325.1 - 0.0016 18.2 1.8 0.034 13.8 1.0 2.6 2 0 0 2 2 2 1 Serglycin Kdo PF06293.9 GAM17325.1 - 0.02 13.9 8.8 0.38 9.7 0.2 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family GDPD PF03009.12 GAM17326.1 - 1.9e-31 109.4 0.0 1.8e-30 106.3 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 GAM17326.1 - 0.058 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF4419 PF14388.1 GAM17327.1 - 9.9e-88 294.2 0.9 9.9e-88 294.2 0.7 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4419) DUF908 PF06012.7 GAM17327.1 - 0.079 12.2 2.9 0.13 11.5 2.0 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) NST1 PF13945.1 GAM17327.1 - 0.81 9.7 6.8 0.11 12.5 0.4 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator HSP20 PF00011.16 GAM17328.1 - 3.5e-17 62.1 1.6 3.4e-09 36.4 0.1 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family BON PF04972.12 GAM17328.1 - 0.042 13.6 0.1 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 BON domain HMA PF00403.21 GAM17328.1 - 0.2 11.8 2.8 0.85 9.8 0.7 2.4 1 1 1 2 2 2 0 Heavy-metal-associated domain BNIP2 PF12496.3 GAM17328.1 - 2.5 8.2 7.1 4.3 7.5 4.9 1.4 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4419 PF14388.1 GAM17329.1 - 9.5e-103 343.5 0.6 1.7e-102 342.6 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Pkinase_Tyr PF07714.12 GAM17330.1 - 1.9e-62 210.6 0.0 2.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM17330.1 - 4.4e-49 166.9 0.0 5.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM17330.1 - 1.6e-15 56.6 0.1 3.1e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 GAM17330.1 - 0.0019 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 GAM17330.1 - 0.032 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Alpha_L_fucos PF01120.12 GAM17331.1 - 2e-111 372.2 4.3 2.3e-111 372.0 3.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Ribosomal_L4 PF00573.17 GAM17332.1 - 3.2e-55 186.5 0.6 4.9e-55 185.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family L51_S25_CI-B8 PF05047.11 GAM17333.1 - 1e-06 28.3 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Cyclin_N PF00134.18 GAM17334.1 - 4.5e-05 23.0 0.1 6.9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAM17334.1 - 0.015 15.7 0.1 0.015 15.7 0.1 2.1 2 0 0 2 2 2 0 Cyclin RRM_1 PF00076.17 GAM17335.1 - 1.3e-21 76.0 0.0 1.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17335.1 - 2.7e-16 59.2 0.0 3.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17335.1 - 9.5e-11 41.3 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM17335.1 - 0.056 13.2 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4167 PF13763.1 GAM17336.1 - 0.039 13.9 1.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Reo_sigmaC PF04582.7 GAM17336.1 - 0.039 13.1 3.6 0.049 12.7 2.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2968 PF11180.3 GAM17336.1 - 0.48 9.7 17.3 0.19 11.0 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Baculo_p24 PF05073.7 GAM17336.1 - 0.74 9.3 14.5 0.13 11.7 4.7 2.1 1 1 1 2 2 2 0 Baculovirus P24 capsid protein DUF3095 PF11294.3 GAM17336.1 - 0.77 8.7 5.1 0.96 8.4 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) TroA PF01297.12 GAM17336.1 - 0.86 8.8 4.5 9 5.4 3.1 2.1 1 1 0 1 1 1 0 Periplasmic solute binding protein family ORF6C PF10552.4 GAM17336.1 - 2.1 8.1 15.2 9.9 5.9 2.2 3.3 2 1 0 3 3 3 0 ORF6C domain Spectrin PF00435.16 GAM17336.1 - 2.5 8.4 17.1 4.2 7.6 6.0 2.5 1 1 1 2 2 2 0 Spectrin repeat FERM_M PF00373.13 GAM17336.1 - 2.5 8.2 6.2 0.71 10.0 0.4 2.2 2 1 0 2 2 2 0 FERM central domain Uds1 PF15456.1 GAM17336.1 - 3.7 7.5 13.9 0.35 10.8 0.7 2.4 2 1 0 2 2 2 0 Up-regulated During Septation DUF342 PF03961.8 GAM17336.1 - 6.6 5.0 20.6 2.9 6.1 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMPIT PF07851.8 GAM17337.1 - 1.5e-96 323.3 5.3 1.7e-96 323.1 3.7 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF2730 PF10805.3 GAM17337.1 - 0.024 14.3 0.8 0.13 12.0 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Cytochrom_B562 PF07361.6 GAM17337.1 - 0.028 14.8 2.1 0.28 11.5 0.0 2.5 2 1 1 3 3 3 0 Cytochrome b562 ALIX_LYPXL_bnd PF13949.1 GAM17337.1 - 0.043 12.7 1.9 0.065 12.1 1.3 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Laminin_II PF06009.7 GAM17337.1 - 0.062 13.0 3.0 0.093 12.4 2.1 1.2 1 0 0 1 1 1 0 Laminin Domain II Occludin_ELL PF07303.8 GAM17337.1 - 0.063 14.0 1.5 1.2 9.8 0.1 2.5 2 1 1 3 3 3 0 Occludin homology domain PspC PF04024.7 GAM17337.1 - 0.47 9.9 2.5 1 8.8 0.0 2.4 2 0 0 2 2 2 0 PspC domain TBPIP PF07106.8 GAM17337.1 - 1.4 8.4 5.7 6.5 6.2 4.0 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 GAM17337.1 - 9.2 6.1 10.0 0.41 10.5 2.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Macro PF01661.16 GAM17338.1 - 2.3e-31 108.1 0.2 4.1e-31 107.3 0.1 1.4 1 0 0 1 1 1 1 Macro domain WWE PF02825.15 GAM17338.1 - 4e-20 71.0 2.2 2.2e-09 36.6 0.1 3.5 3 0 0 3 3 3 3 WWE domain DUF1454 PF07305.7 GAM17338.1 - 0.022 13.8 1.2 0.045 12.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) DUF2201_N PF13203.1 GAM17338.1 - 2.1 7.4 6.6 5 6.2 4.6 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain MSA-2c PF12238.3 GAM17340.1 - 0.021 14.4 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Rubella_E2 PF05749.6 GAM17340.1 - 0.31 10.2 3.3 0.38 9.9 2.3 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 PLRV_ORF5 PF01690.12 GAM17340.1 - 1.4 7.9 9.5 2 7.4 6.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Med12 PF09497.5 GAM17342.1 - 5.4e-15 55.1 0.0 1.8e-13 50.2 0.0 2.8 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 GAM17342.1 - 1.2e-12 47.0 0.1 1.2e-12 47.0 0.0 3.2 4 1 0 4 4 4 1 Eukaryotic Mediator 12 subunit domain Serglycin PF04360.7 GAM17342.1 - 0.012 15.3 0.9 0.59 9.8 0.0 2.5 2 0 0 2 2 2 0 Serglycin FDF PF09532.5 GAM17343.1 - 4.4e-11 43.2 10.2 4.4e-11 43.2 7.1 2.8 3 0 0 3 3 3 1 FDF domain P_C PF06640.6 GAM17343.1 - 0.046 13.7 0.8 0.091 12.7 0.5 1.5 1 0 0 1 1 1 0 P protein C-terminus Yeast-kill-tox PF09207.6 GAM17344.1 - 0.057 13.8 1.1 0.079 13.4 0.8 1.2 1 0 0 1 1 1 0 Yeast killer toxin Lung_7-TM_R PF06814.8 GAM17345.1 - 9.7e-12 44.4 27.9 1.9e-11 43.4 19.3 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 GAM17345.1 - 9e-09 34.8 22.9 9e-09 34.8 15.9 2.0 2 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Amnionless PF14828.1 GAM17345.1 - 1.7 7.0 3.4 1.4 7.3 0.2 2.0 2 0 0 2 2 2 0 Amnionless Asparaginase_2 PF01112.13 GAM17346.1 - 2.7e-28 98.6 8.5 1.3e-18 66.7 2.5 3.4 2 1 0 2 2 2 2 Asparaginase PBP1_TM PF14812.1 GAM17346.1 - 0.69 10.2 10.5 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1253 PF06862.7 GAM17348.1 - 8.8e-141 469.2 9.4 8.8e-141 469.2 6.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Glyco_transf_7N PF13733.1 GAM17348.1 - 0.00034 20.0 1.5 0.012 14.9 0.1 2.5 2 0 0 2 2 2 2 N-terminal region of glycosyl transferase group 7 Podoplanin PF05808.6 GAM17349.1 - 3.5e-05 23.4 4.2 8.7e-05 22.1 2.9 1.6 1 0 0 1 1 1 1 Podoplanin DUF676 PF05057.9 GAM17350.1 - 1.9e-43 148.3 0.1 3.7e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 GAM17350.1 - 4.7e-08 32.9 0.0 2.8e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAM17350.1 - 2.5e-07 30.8 0.0 3.7e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAM17350.1 - 2.7e-07 30.3 0.0 7.4e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAM17350.1 - 7.9e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM17350.1 - 3.3e-05 23.5 0.0 6.3e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 GAM17350.1 - 0.00049 19.5 0.0 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 GAM17350.1 - 0.00086 18.3 0.0 0.002 17.1 0.0 1.6 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 GAM17350.1 - 0.0033 16.7 0.0 0.027 13.7 0.0 2.4 2 1 0 2 2 2 1 Lipase (class 2) DUF915 PF06028.6 GAM17350.1 - 0.004 16.2 0.1 0.27 10.2 0.0 2.9 3 1 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 GAM17350.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.7 GAM17350.1 - 0.035 13.8 0.1 0.084 12.5 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) BTB_2 PF02214.17 GAM17351.1 - 8e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.11 GAM17352.1 - 4.6e-18 65.5 0.6 9.7e-18 64.5 0.4 1.5 1 0 0 1 1 1 1 TLD BTB_2 PF02214.17 GAM17352.1 - 1.1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BAR PF03114.13 GAM17353.1 - 2.6e-18 66.3 1.4 4.3e-18 65.6 1.0 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 GAM17353.1 - 5.8e-15 54.5 0.0 9.1e-15 53.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM17353.1 - 1.5e-14 53.1 0.1 2.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM17353.1 - 1e-11 44.0 0.0 1.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RhoGEF PF00621.15 GAM17353.1 - 0.015 15.2 0.5 0.025 14.4 0.4 1.3 1 0 0 1 1 1 0 RhoGEF domain TPR_MLP1_2 PF07926.7 GAM17353.1 - 0.23 11.2 5.9 0.26 11.0 2.4 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 GAM17353.1 - 0.3 11.4 2.2 0.96 9.8 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) MFS_1 PF07690.11 GAM17354.1 - 3.6e-29 101.5 47.0 4e-23 81.6 18.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 GAM17354.1 - 2.6e-21 75.7 9.7 2.6e-21 75.7 6.7 3.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 PUCC PF03209.10 GAM17354.1 - 0.0011 17.7 0.7 0.0011 17.7 0.5 2.5 2 1 0 2 2 2 1 PUCC protein Sugar_tr PF00083.19 GAM17354.1 - 0.046 12.3 30.9 0.0043 15.6 7.0 2.8 1 1 2 3 3 3 0 Sugar (and other) transporter DUF2306 PF10067.4 GAM17354.1 - 3.3 7.8 10.6 0.19 11.8 2.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Mnd1 PF03962.10 GAM17355.1 - 3.7e-52 176.7 8.0 4.3e-52 176.5 5.5 1.1 1 0 0 1 1 1 1 Mnd1 family CheY-binding PF09078.6 GAM17355.1 - 0.006 16.5 0.3 0.012 15.6 0.2 1.5 1 0 0 1 1 1 1 CheY binding S10_plectin PF03501.10 GAM17355.1 - 0.0065 16.3 0.2 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Plectin/S10 domain DUF848 PF05852.6 GAM17355.1 - 0.0071 16.2 3.6 0.0071 16.2 2.5 1.7 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) Dsl1_N PF11988.3 GAM17355.1 - 0.016 14.1 3.0 0.57 9.0 0.3 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal DUF342 PF03961.8 GAM17355.1 - 0.024 13.0 2.7 0.026 12.9 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Flu_NS2 PF00601.14 GAM17355.1 - 0.029 14.5 2.1 0.045 13.9 0.2 2.1 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) DivIC PF04977.10 GAM17355.1 - 0.083 12.3 13.6 0.98 8.9 2.9 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF4298 PF14131.1 GAM17355.1 - 0.12 12.3 5.7 0.21 11.4 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) TBPIP PF07106.8 GAM17355.1 - 0.18 11.3 12.9 13 5.2 9.0 3.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1910 PF08928.5 GAM17355.1 - 0.34 10.9 3.0 0.21 11.6 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) IncA PF04156.9 GAM17355.1 - 0.38 10.3 11.4 0.032 13.8 4.8 1.4 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 GAM17355.1 - 3.1 6.6 7.8 3.8 6.3 5.0 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 GAM17355.1 - 6.7 6.7 15.9 4.4 7.3 2.2 2.5 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit MutS_IV PF05190.13 GAM17355.1 - 8.5 6.6 8.1 8.7 6.5 0.5 2.8 3 1 0 3 3 3 0 MutS family domain IV Arf PF00025.16 GAM17356.1 - 2.3e-56 189.7 0.1 2.7e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM17356.1 - 1.7e-15 56.8 0.0 1.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM17356.1 - 1.4e-13 50.4 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAM17356.1 - 6.4e-10 39.5 0.0 1.1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM17356.1 - 1.5e-05 24.2 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM17356.1 - 0.0018 17.7 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 GAM17356.1 - 0.0026 16.5 0.6 0.71 8.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 GAM17356.1 - 0.0072 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM17356.1 - 0.0086 15.9 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 GAM17356.1 - 0.12 11.8 0.1 0.54 9.7 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 GAM17356.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PPR_2 PF13041.1 GAM17357.1 - 4.7e-21 74.5 10.6 0.00031 20.6 0.0 10.4 7 3 4 11 11 11 5 PPR repeat family PPR_3 PF13812.1 GAM17357.1 - 6.6e-14 50.9 9.8 0.0015 18.6 0.0 9.2 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 GAM17357.1 - 1.2e-12 46.8 7.1 0.33 11.0 0.0 9.3 10 0 0 10 10 10 3 PPR repeat TPR_12 PF13424.1 GAM17357.1 - 0.0031 17.4 0.9 0.15 12.0 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_1 PF12854.2 GAM17357.1 - 0.043 13.3 0.0 34 4.0 0.0 4.1 4 0 0 4 4 4 0 PPR repeat TPR_7 PF13176.1 GAM17357.1 - 0.055 13.2 0.8 15 5.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM17357.1 - 0.086 13.5 0.7 71 4.4 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Senescence PF06911.7 GAM17358.1 - 7.5e-25 87.6 5.6 9.8e-25 87.2 3.5 1.5 1 1 0 1 1 1 1 Senescence-associated protein Ribosomal_L24e PF01246.15 GAM17359.1 - 9.2e-21 73.4 1.4 2.2e-20 72.2 1.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_S8e PF01201.17 GAM17360.1 - 2.2e-46 157.2 3.2 2.7e-46 157.0 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e DUF1676 PF07898.8 GAM17360.1 - 0.13 12.5 0.9 0.26 11.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DEP PF00610.16 GAM17361.1 - 3.3e-08 33.1 0.0 1.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PP2C_2 PF13672.1 GAM17361.1 - 3e-06 26.8 0.3 9.1e-05 21.9 0.0 3.0 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM17361.1 - 0.0078 15.9 0.0 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Rubis-subs-bind PF09273.6 GAM17363.1 - 2.1e-12 47.0 6.0 1.6e-10 40.9 2.3 3.6 2 1 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.23 GAM17363.1 - 1.5e-05 25.3 0.1 0.00028 21.2 0.0 3.1 3 1 0 3 3 3 1 SET domain Med15 PF09606.5 GAM17363.1 - 1.8 6.6 26.3 1.2 7.1 1.5 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CH PF00307.26 GAM17365.1 - 6.8e-12 45.3 0.0 6.8e-12 45.3 0.0 3.6 4 0 0 4 4 4 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM17365.1 - 0.0016 18.0 0.2 0.013 15.1 0.0 2.7 2 1 1 3 3 3 1 CAMSAP CH domain PsbY PF06298.6 GAM17366.1 - 0.011 15.1 0.4 0.04 13.4 0.3 1.9 1 1 0 1 1 1 0 Photosystem II protein Y (PsbY) PCI PF01399.22 GAM17368.1 - 3.8e-11 43.2 2.3 6.1e-11 42.5 0.1 2.5 2 1 1 3 3 3 1 PCI domain Paf67 PF10255.4 GAM17369.1 - 2.1e-123 412.1 9.7 3.5e-123 411.4 6.7 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.22 GAM17369.1 - 0.00032 20.9 0.2 0.001 19.3 0.2 1.8 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.1 GAM17369.1 - 0.0011 19.2 1.0 0.076 13.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM17369.1 - 0.024 14.5 2.0 0.047 13.6 0.4 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 GAM17369.1 - 0.14 11.9 3.7 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 COP9 signalosome, subunit CSN8 Fis1_TPR_C PF14853.1 GAM17369.1 - 0.59 10.0 5.2 0.71 9.7 1.6 2.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LSM PF01423.17 GAM17370.1 - 9.2e-18 63.5 0.2 1.2e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 GAM17370.1 - 0.033 13.7 0.1 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Cyclin_N PF00134.18 GAM17371.1 - 0.00057 19.4 0.2 0.00057 19.4 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAM17371.1 - 0.81 10.0 15.5 0.044 14.2 5.4 2.7 2 1 0 2 2 2 0 Cyclin Actin PF00022.14 GAM17372.1 - 5.6e-39 133.6 0.0 7.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Actin RasGAP PF00616.14 GAM17373.1 - 6.2e-49 166.3 0.4 6.2e-49 166.3 0.3 2.8 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAM17373.1 - 8.3e-31 106.5 13.2 3.6e-30 104.5 9.2 2.2 1 0 0 1 1 1 1 RasGAP C-terminus Latarcin PF10279.4 GAM17373.1 - 0.11 12.6 4.8 0.63 10.2 1.0 2.9 2 0 0 2 2 2 0 Latarcin precursor DivIC PF04977.10 GAM17373.1 - 4.4 6.8 11.1 24 4.5 0.2 3.2 2 0 0 2 2 2 0 Septum formation initiator Snapin_Pallidin PF14712.1 GAM17373.1 - 5.1 7.4 17.5 0.38 11.0 3.1 4.4 3 1 1 4 4 4 0 Snapin/Pallidin zf-rbx1 PF12678.2 GAM17374.1 - 1.1e-34 118.3 14.4 1.3e-34 118.0 9.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM17374.1 - 2.2e-17 62.6 10.5 2.8e-17 62.3 7.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 GAM17374.1 - 2e-07 30.7 12.5 1.3e-06 28.0 8.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM17374.1 - 0.00083 18.9 12.8 0.019 14.6 8.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM17374.1 - 0.0036 16.9 10.3 0.37 10.5 7.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM17374.1 - 0.03 14.3 13.4 1 9.4 9.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 GAM17374.1 - 0.15 11.9 9.5 1.3 9.0 6.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 GAM17374.1 - 0.26 11.0 7.1 6.5 6.5 5.0 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Flexi_CP PF00286.15 GAM17374.1 - 0.42 10.3 2.8 0.53 9.9 0.7 1.8 1 1 1 2 2 2 0 Viral coat protein zf-HC5HC2H PF13771.1 GAM17374.1 - 0.7 10.0 10.6 58 3.9 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 GAM17374.1 - 0.79 9.4 12.7 8.6 6.1 8.8 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 GAM17374.1 - 3 7.9 11.7 12 5.9 8.1 2.0 1 1 0 1 1 1 0 PHD-zinc-finger like domain PGK PF00162.14 GAM17375.1 - 3.8e-149 496.4 0.7 4.3e-149 496.2 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3172 PF11371.3 GAM17375.1 - 0.083 12.3 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) Mucin PF01456.12 GAM17376.1 - 0.0035 17.1 2.3 0.0046 16.7 1.6 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.7 GAM17376.1 - 0.67 7.6 2.0 0.74 7.4 1.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim17 PF02466.14 GAM17377.1 - 1.9e-05 24.7 0.3 2.1e-05 24.5 0.2 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SAYSvFN PF10260.4 GAM17377.1 - 0.045 13.5 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) p450 PF00067.17 GAM17378.1 - 1.9e-66 224.5 0.3 3e-66 223.8 0.2 1.3 1 1 0 1 1 1 1 Cytochrome P450 Hexapep PF00132.19 GAM17378.1 - 0.12 11.9 0.6 0.76 9.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Cation_ATPase_C PF00689.16 GAM17379.1 - 2.1e-11 43.6 11.8 2.1e-11 43.6 8.2 3.1 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM17379.1 - 1.2e-05 25.8 0.0 2.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM17379.1 - 0.17 10.9 7.0 0.18 10.8 0.0 2.9 3 0 0 3 3 3 0 E1-E2 ATPase RseC_MucC PF04246.7 GAM17379.1 - 0.21 11.1 2.1 0.86 9.1 1.4 2.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Med19 PF10278.4 GAM17379.1 - 0.73 9.4 25.8 1.3 8.7 6.2 2.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 EGF_2 PF07974.8 GAM17380.1 - 0.27 11.4 39.4 0.086 13.0 9.9 3.3 3 0 0 3 3 3 0 EGF-like domain ABC2_membrane PF01061.19 GAM17381.1 - 1.1e-91 305.6 69.1 3.5e-48 163.5 19.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM17381.1 - 4e-38 130.8 0.0 8.8e-19 68.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM17381.1 - 2.8e-28 97.5 12.1 3e-22 78.2 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAM17381.1 - 1.7e-15 56.9 51.8 1.8e-10 40.4 8.0 3.5 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAM17381.1 - 1.5e-08 34.5 0.0 3.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 GAM17381.1 - 1.1e-06 28.0 0.6 0.0028 17.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM17381.1 - 1.3e-06 27.6 0.1 0.00029 20.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 GAM17381.1 - 4.9e-05 23.4 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM17381.1 - 0.00032 20.1 0.1 0.0046 16.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM17381.1 - 0.00077 19.6 0.4 0.81 9.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM17381.1 - 0.0019 18.5 0.1 0.66 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAM17381.1 - 0.003 17.0 0.5 0.068 12.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAM17381.1 - 0.0045 17.0 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAM17381.1 - 0.0063 17.3 0.0 0.82 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM17381.1 - 0.01 15.8 0.1 6.5 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM17381.1 - 0.013 15.3 0.0 0.88 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAM17381.1 - 0.022 14.9 0.1 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 GAM17381.1 - 0.026 13.5 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 GAM17381.1 - 0.042 13.8 1.4 0.55 10.1 0.3 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAM17381.1 - 0.058 13.0 0.1 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 GAM17381.1 - 0.094 12.3 0.2 1.3 8.6 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 GAM17381.1 - 0.095 12.6 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 GAM17381.1 - 0.11 11.9 0.0 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 GAM17381.1 - 0.13 11.7 0.7 0.95 8.9 0.3 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 GAM17381.1 - 0.15 11.8 0.1 25 4.7 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 GAM17381.1 - 0.23 11.0 0.1 6.4 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 GAM17382.1 - 4e-12 45.5 10.1 0.0004 19.9 0.1 6.9 5 1 1 6 6 6 3 TPR repeat TPR_1 PF00515.23 GAM17382.1 - 6.5e-07 28.6 6.2 0.16 11.6 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM17382.1 - 1.2e-06 28.2 5.4 1.8 8.9 0.0 5.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM17382.1 - 9.8e-06 25.1 8.7 0.28 11.2 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM17382.1 - 0.00084 19.2 17.4 0.16 11.8 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM17382.1 - 0.0026 18.2 5.5 10 7.0 0.0 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17382.1 - 0.0033 17.7 19.7 0.24 11.7 0.0 6.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM17382.1 - 0.027 14.2 14.8 1.1 9.2 0.0 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Zip PF02535.17 GAM17382.1 - 0.23 10.4 3.6 1.2 8.1 0.8 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1206 PF06724.6 GAM17384.1 - 8.4e-09 35.0 17.6 0.0011 18.6 0.4 3.6 3 1 0 3 3 3 3 Domain of Unknown Function (DUF1206) Viral_Beta_CD PF04530.7 GAM17384.1 - 0.15 12.2 0.2 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Viral Beta C/D like family DUF202 PF02656.10 GAM17384.1 - 9 6.6 11.1 4.5 7.5 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) EF-hand_7 PF13499.1 GAM17385.1 - 3.4e-06 27.1 0.7 6.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM17385.1 - 4.8e-05 22.9 0.6 0.00048 19.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 GAM17385.1 - 0.00015 20.7 0.0 0.00058 18.9 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 GAM17385.1 - 0.001 18.3 0.1 0.001 18.3 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.6 GAM17385.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like EF_assoc_1 PF08355.7 GAM17385.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 EF hand associated EF-hand_8 PF13833.1 GAM17385.1 - 0.12 12.0 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair FMN_red PF03358.10 GAM17386.1 - 1.7e-29 102.2 0.0 2.7e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM17386.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold AARP2CN PF08142.7 GAM17386.1 - 0.05 13.1 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 AARP2CN (NUC121) domain Arm PF00514.18 GAM17387.1 - 3.4e-35 118.6 19.4 0.00036 20.2 0.0 12.8 13 1 0 13 13 13 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM17387.1 - 1.3e-22 79.8 2.5 2.7e-05 24.3 0.2 7.2 2 1 7 9 9 9 7 HEAT repeats HEAT PF02985.17 GAM17387.1 - 1.6e-21 74.3 17.7 0.02 14.9 0.0 10.9 13 0 0 13 13 13 6 HEAT repeat HEAT_EZ PF13513.1 GAM17387.1 - 2.9e-12 46.6 5.8 0.18 12.3 0.1 8.6 6 4 4 10 10 10 4 HEAT-like repeat V-ATPase_H_C PF11698.3 GAM17387.1 - 1.4e-06 28.1 12.6 0.05 13.5 0.1 6.3 4 1 3 8 8 8 2 V-ATPase subunit H Ric8 PF10165.4 GAM17387.1 - 0.0014 17.5 13.1 0.21 10.3 0.9 4.2 2 1 1 4 4 4 3 Guanine nucleotide exchange factor synembryn RICTOR_V PF14668.1 GAM17387.1 - 0.0091 15.9 0.8 3.3 7.6 0.0 4.6 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.4 GAM17387.1 - 0.045 13.4 13.2 18 5.1 0.7 5.3 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.3 GAM17387.1 - 0.73 9.5 15.3 8.9 6.0 0.2 5.0 2 1 3 6 6 6 0 Domain of unknown function (DUF3361) Dicty_CTDC PF00526.13 GAM17388.1 - 1.2e-145 471.9 365.1 9.1e-11 41.3 8.4 19.5 20 0 0 20 20 20 19 Dictyostelium (slime mold) repeat Metallophos PF00149.23 GAM17388.1 - 3.9 6.8 14.4 1.5e+04 -8.1 10.0 5.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase 7tm_7 PF08395.7 GAM17389.1 - 0.0052 15.8 1.4 0.0066 15.5 1.0 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor AA_kinase PF00696.23 GAM17390.1 - 9.2e-22 77.7 0.3 6.2e-21 75.0 0.1 2.1 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.19 GAM17390.1 - 3.8e-21 75.6 0.0 9.8e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF619 PF04768.8 GAM17390.1 - 5.9e-14 51.8 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) LBP_BPI_CETP PF01273.20 GAM17390.1 - 0.0014 17.9 0.0 0.0045 16.3 0.0 1.9 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DapB_N PF01113.15 GAM17390.1 - 0.048 13.5 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus LRR_6 PF13516.1 GAM17391.1 - 1.3e-30 101.9 46.4 0.00051 19.8 0.2 11.6 11 0 0 11 11 11 10 Leucine Rich repeat LRR_4 PF12799.2 GAM17391.1 - 2e-12 46.4 49.9 0.0007 19.1 1.9 7.1 4 2 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM17391.1 - 5.9e-10 37.7 36.6 0.087 12.9 0.2 10.7 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 GAM17391.1 - 6.4e-07 28.5 34.6 0.8 10.1 0.1 11.3 12 0 0 12 12 12 2 Leucine rich repeat LRR_8 PF13855.1 GAM17391.1 - 4e-06 26.4 37.1 0.059 13.1 0.1 6.7 5 2 0 5 5 5 4 Leucine rich repeat RL11D PF11088.3 GAM17391.1 - 3.5 7.4 7.3 1.7 8.5 0.1 3.9 2 2 2 4 4 4 0 Glycoprotein encoding membrane proteins RL5A and RL6 PhzC-PhzF PF02567.11 GAM17392.1 - 7.6e-53 179.5 0.0 9e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 GAM17392.1 - 7.6e-08 31.5 0.0 2.2e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Proline racemase Arf PF00025.16 GAM17393.1 - 2.4e-68 228.8 0.0 2.7e-68 228.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM17393.1 - 3.1e-16 59.1 0.0 3.6e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM17393.1 - 6e-15 55.0 0.0 6.8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17393.1 - 4.4e-11 43.3 0.0 6.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 GAM17393.1 - 6.5e-10 38.2 0.4 1.6e-07 30.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM17393.1 - 2.2e-08 33.5 0.0 2.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM17393.1 - 4.1e-06 26.7 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM17393.1 - 0.018 14.9 0.3 4 7.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 GAM17393.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 GAM17393.1 - 0.052 13.0 0.2 0.14 11.6 0.1 1.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 GAM17393.1 - 0.08 12.3 0.0 3.1 7.2 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM17393.1 - 0.086 12.1 0.2 0.34 10.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 GAM17393.1 - 0.13 12.5 0.0 1.4 9.2 0.0 2.1 1 1 0 1 1 1 0 ABC transporter Ank_2 PF12796.2 GAM17394.1 - 4.2e-25 87.8 5.7 3.7e-10 39.9 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17394.1 - 1.4e-22 79.6 18.4 5.8e-06 26.6 0.1 6.0 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17394.1 - 2.3e-22 78.4 11.4 0.021 15.0 0.1 7.9 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17394.1 - 2.2e-18 64.4 10.0 0.6 10.5 0.0 8.2 5 2 3 8 8 8 7 Ankyrin repeat Ank PF00023.25 GAM17394.1 - 1.9e-15 55.7 9.0 0.54 10.1 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat DUF2462 PF09495.5 GAM17394.1 - 0.022 15.4 0.2 12 6.6 0.0 4.1 4 1 0 5 5 5 0 Protein of unknown function (DUF2462) DUF249 PF03158.8 GAM17394.1 - 0.031 13.8 0.2 0.51 9.8 0.0 2.7 1 1 0 2 2 2 0 Multigene family 530 protein Prok-JAB PF14464.1 GAM17394.1 - 0.88 9.1 5.9 7.2 6.2 4.1 2.2 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain Ank_2 PF12796.2 GAM17395.1 - 6.8e-30 103.2 7.5 5.6e-10 39.4 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17395.1 - 1.2e-25 89.3 13.3 3.7e-07 30.4 0.1 5.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM17395.1 - 4.9e-23 79.7 1.9 5.7e-06 25.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat RGS PF00615.14 GAM17395.1 - 1.1e-19 70.6 8.8 3e-15 56.3 0.2 3.8 4 0 0 4 4 4 2 Regulator of G protein signaling domain Ank_5 PF13857.1 GAM17395.1 - 6.7e-19 67.4 8.2 2.3e-07 30.8 0.2 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17395.1 - 1.7e-17 61.7 7.2 0.0013 18.7 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat PLC-beta_C PF08703.5 GAM17395.1 - 0.051 13.2 2.1 0.11 12.1 1.4 1.5 1 0 0 1 1 1 0 PLC-beta C terminal Dala_Dala_lig_C PF07478.8 GAM17395.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus SopA PF13981.1 GAM17395.1 - 0.06 13.3 2.6 0.17 11.9 0.7 2.5 2 0 0 2 2 2 0 SopA-like central domain Mucin PF01456.12 GAM17395.1 - 0.29 10.9 29.0 0.75 9.5 20.1 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Spatacsin_C PF14649.1 GAM17396.1 - 1.1e-96 323.2 5.5 2e-96 322.3 3.8 1.4 1 0 0 1 1 1 1 Spatacsin C-terminus Nucleoplasmin PF03066.10 GAM17397.1 - 0.0086 15.5 24.8 0.14 11.6 4.6 2.3 2 0 0 2 2 2 2 Nucleoplasmin Mannosyl_trans3 PF11051.3 GAM17397.1 - 0.1 11.8 1.9 0.11 11.7 0.1 1.9 2 1 1 3 3 3 0 Mannosyltransferase putative RXT2_N PF08595.6 GAM17397.1 - 0.3 10.8 17.7 1.2 8.9 3.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.9 GAM17397.1 - 0.58 8.1 15.8 0.8 7.6 1.8 2.1 2 0 0 2 2 2 0 CDC45-like protein CobT PF06213.7 GAM17397.1 - 0.98 8.4 21.1 1.5 7.9 4.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 GAM17397.1 - 1.3 7.9 13.6 0.44 9.4 0.4 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 GAM17397.1 - 6.7 7.0 32.3 0.4 10.9 3.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 GAM17397.1 - 7.6 6.7 25.3 0.88 9.7 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Voldacs PF03517.8 GAM17397.1 - 7.7 6.3 16.2 1 9.1 2.0 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Sporozoite_P67 PF05642.6 GAM17397.1 - 7.8 4.2 16.2 1.3 6.7 4.4 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TLP-20 PF06088.6 GAM17397.1 - 8.1 6.0 17.9 0.078 12.6 0.5 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SspB PF04386.8 GAM17397.1 - 9.7 5.7 10.1 6.2 6.4 1.3 2.2 2 0 0 2 2 2 0 Stringent starvation protein B MxiH PF09392.5 GAM17398.1 - 0.037 14.6 3.1 0.16 12.5 2.1 2.0 1 1 0 1 1 1 0 Type III secretion needle MxiH like Prolamin_like PF05617.6 GAM17400.1 - 0.046 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Prolamin-like Peptidase_M1 PF01433.15 GAM17401.1 - 1.1e-116 390.1 3.6 1.1e-116 390.1 2.5 2.0 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 GAM17401.1 - 7.1e-31 107.6 3.3 1.3e-30 106.7 2.3 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAM17401.1 - 1.9e-15 57.0 0.0 5.3e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 GAM17401.1 - 0.0055 16.4 0.2 0.017 14.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1360) DUF2463 PF09591.5 GAM17401.1 - 0.0097 15.5 1.6 0.024 14.2 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Peptidase_M1 PF01433.15 GAM17402.1 - 3.2e-121 405.1 1.6 4.2e-121 404.6 1.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 GAM17402.1 - 2.4e-17 63.1 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase MA superfamily ERAP1_C PF11838.3 GAM17402.1 - 3.7e-17 62.5 0.1 7.1e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF1360 PF07098.6 GAM17402.1 - 0.035 13.8 0.4 0.083 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) MBOAT PF03062.14 GAM17403.1 - 1.2e-34 119.8 36.0 1.2e-34 119.8 24.9 2.4 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF2370 PF10176.4 GAM17403.1 - 0.00016 21.1 0.8 0.00038 19.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF912 PF06024.7 GAM17403.1 - 0.014 15.4 0.4 0.014 15.4 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zip PF02535.17 GAM17403.1 - 0.028 13.4 5.9 0.085 11.8 4.1 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter ATG27 PF09451.5 GAM17403.1 - 0.062 12.5 0.2 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2839 PF10999.3 GAM17403.1 - 0.42 10.6 2.3 3 7.9 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) VPS9 PF02204.13 GAM17404.1 - 3.1e-08 33.5 0.0 8.5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Adaptin_binding PF10199.4 GAM17404.1 - 4.7 7.5 10.2 0.11 12.7 0.8 2.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Glyco_trans_1_4 PF13692.1 GAM17405.1 - 4.3e-19 69.0 0.0 2.9e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 GAM17405.1 - 3.8e-07 29.6 0.0 8.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM17405.1 - 0.00012 22.2 0.1 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain SR-25 PF10500.4 GAM17405.1 - 0.38 10.1 8.1 0.56 9.6 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2087 PF09860.4 GAM17406.1 - 0.039 13.6 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) zf-C2H2 PF00096.21 GAM17406.1 - 1.5 9.3 18.7 1.4 9.3 0.2 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type GTP_EFTU PF00009.22 GAM17407.1 - 3.9e-38 130.7 0.1 7e-38 129.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 GAM17407.1 - 3.3e-35 119.9 0.1 7.5e-35 118.8 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 GAM17407.1 - 5.6e-12 45.6 0.4 1.8e-11 43.9 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM17407.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase HI0933_like PF03486.9 GAM17408.1 - 3.8e-87 292.4 0.0 4.7e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM17408.1 - 3.5e-06 26.1 0.2 0.12 11.1 0.0 3.2 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 GAM17408.1 - 1e-05 25.6 0.0 0.00012 22.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM17408.1 - 3.1e-05 23.0 0.5 0.021 13.7 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM17408.1 - 0.00012 22.0 0.4 0.00049 20.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM17408.1 - 0.00028 20.8 1.0 0.029 14.2 0.7 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM17408.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 GAM17408.1 - 0.034 13.0 1.5 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Strep_67kDa_ant PF06100.6 GAM17408.1 - 0.09 11.1 0.1 4.4 5.5 0.1 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family DNase_II PF03265.10 GAM17409.1 - 1e-85 287.6 0.1 1.1e-85 287.4 0.1 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II C1_1 PF00130.17 GAM17410.1 - 0.00084 19.0 1.5 0.0021 17.7 1.1 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 GAM17410.1 - 0.0017 17.5 0.8 0.0017 17.5 0.6 2.1 3 0 0 3 3 3 1 PHD-finger DDE_Tnp_1_7 PF13843.1 GAM17410.1 - 0.0051 15.9 0.0 0.0051 15.9 0.0 1.6 2 0 0 2 2 2 1 Transposase IS4 Prok-RING_1 PF14446.1 GAM17410.1 - 0.015 15.0 2.2 0.034 13.8 1.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 GAM17410.1 - 0.2 11.3 3.7 0.45 10.2 1.6 2.2 2 0 0 2 2 2 0 PHD-finger Dicty_CTDC PF00526.13 GAM17412.1 - 0.00014 21.5 17.5 0.00032 20.4 3.4 12.0 11 2 1 12 12 12 3 Dictyostelium (slime mold) repeat TMEM154 PF15102.1 GAM17412.1 - 0.96 9.1 3.7 1.6 8.4 2.5 1.3 1 0 0 1 1 1 0 TMEM154 protein family Sporozoite_P67 PF05642.6 GAM17412.1 - 3.9 5.2 12.3 4.1 5.1 8.4 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen gpUL132 PF11359.3 GAM17412.1 - 4.6 6.5 14.1 7.4 5.8 9.8 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Asp PF00026.18 GAM17413.1 - 3.1e-20 72.6 2.0 5.6e-20 71.8 1.4 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM17413.1 - 8.1e-12 44.9 0.0 3.9e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 GAM17413.1 - 6.5e-08 32.6 1.6 1.4e-07 31.6 1.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF3443 PF11925.3 GAM17413.1 - 0.0036 16.0 0.4 0.025 13.2 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3443) Asp_protease_2 PF13650.1 GAM17413.1 - 0.043 14.3 0.3 6.4 7.3 0.0 3.3 4 0 0 4 4 4 0 Aspartyl protease FNIP PF05725.7 GAM17415.1 - 3.5e-39 132.4 18.6 1.5e-08 34.4 0.2 7.0 5 2 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 GAM17415.1 - 0.049 13.5 0.6 0.35 10.8 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1769) PA14 PF07691.7 GAM17416.1 - 2.3e-33 114.8 2.0 3.2e-11 43.0 0.0 3.3 3 0 0 3 3 3 3 PA14 domain DUF1777 PF08648.7 GAM17417.1 - 0.00014 21.6 28.5 0.00014 21.6 19.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) PAT1 PF09770.4 GAM17417.1 - 0.0011 17.3 66.4 0.0017 16.6 46.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 zf-CCHC PF00098.18 GAM17417.1 - 0.0022 17.8 1.2 0.0044 16.8 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle MIP-T3 PF10243.4 GAM17417.1 - 5.4 5.3 43.7 0.044 12.2 7.6 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Apis_Csd PF11671.3 GAM17417.1 - 9 6.0 28.7 0.62 9.8 9.6 3.0 2 0 0 2 2 2 0 Complementary sex determiner protein Cytochrom_C_asm PF01578.15 GAM17418.1 - 0.17 11.4 3.8 0.19 11.2 2.6 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF2749 PF10907.3 GAM17418.1 - 0.83 9.5 9.4 1.8 8.5 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF4342 PF14242.1 GAM17418.1 - 5.2 6.9 12.7 9.9 6.0 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) SK_channel PF03530.9 GAM17418.1 - 6.7 6.5 8.8 6.6 6.5 5.4 1.6 1 1 0 1 1 1 0 Calcium-activated SK potassium channel MHYT PF03707.11 GAM17418.1 - 7 6.8 10.0 1 9.5 3.7 1.9 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Cyclin_N PF00134.18 GAM17419.1 - 1.2e-06 28.1 0.2 1.2e-06 28.1 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain RecO_C PF02565.10 GAM17419.1 - 0.074 12.9 0.1 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 Recombination protein O C terminal MCM PF00493.18 GAM17420.1 - 2.4e-133 444.0 0.0 4.8e-133 443.0 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM17420.1 - 2e-19 70.2 1.3 4.4e-19 69.1 0.4 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM17420.1 - 3.1e-07 29.7 0.1 0.00012 21.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM17420.1 - 6.8e-06 25.8 0.0 2.7e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM17420.1 - 0.0012 18.3 0.1 0.012 15.1 0.0 2.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM17420.1 - 0.12 11.8 0.0 14 5.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain GFRP PF06399.8 GAM17421.1 - 0.039 13.5 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF1914 PF08932.5 GAM17421.1 - 0.089 12.8 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1914) CPSase_L_D2 PF02786.12 GAM17422.1 - 2.6e-78 262.1 0.1 4.7e-78 261.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAM17422.1 - 5.1e-42 142.4 0.1 1.2e-41 141.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM17422.1 - 3.7e-37 126.5 0.0 1e-36 125.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 GAM17422.1 - 1.4e-16 59.8 0.2 3.3e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAM17422.1 - 1.2e-15 57.6 0.0 3.4e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM17422.1 - 6.9e-13 48.0 0.0 1.3e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAM17422.1 - 1.5e-09 37.5 0.0 7.1e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAM17422.1 - 1.5e-07 30.9 0.0 3.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAM17422.1 - 2.1e-06 27.6 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAM17422.1 - 0.00068 19.2 0.0 0.0035 16.9 0.0 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_5 PF13549.1 GAM17422.1 - 0.0016 17.6 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PP_kinase_N PF13089.1 GAM17422.1 - 0.036 14.1 0.1 0.29 11.2 0.0 2.5 3 0 0 3 3 2 0 Polyphosphate kinase N-terminal domain HlyD_2 PF12700.2 GAM17422.1 - 0.063 12.4 0.0 0.37 9.9 0.0 2.0 1 1 1 2 2 2 0 HlyD family secretion protein AP_endonuc_2 PF01261.19 GAM17422.1 - 0.12 11.6 0.0 6.6 5.9 0.0 2.6 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel DOCK-C2 PF14429.1 GAM17423.1 - 6.6e-54 182.3 3.7 6.6e-54 182.3 2.6 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 GAM17423.1 - 1e-50 171.5 0.2 2.4e-50 170.2 0.2 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis PA14 PF07691.7 GAM17424.1 - 8.9e-07 28.6 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM17424.1 - 0.018 14.8 7.6 0.018 14.8 5.2 12.6 13 1 0 13 13 13 0 Dictyostelium (slime mold) repeat Sporozoite_P67 PF05642.6 GAM17424.1 - 0.038 11.8 5.9 0.062 11.1 4.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.1 GAM17424.1 - 0.58 9.8 14.7 1 9.0 10.2 1.4 1 0 0 1 1 1 0 TMEM154 protein family Thioredoxin PF00085.15 GAM17426.1 - 4.4e-36 122.6 0.3 9.4e-26 89.5 0.1 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 GAM17426.1 - 3.3e-19 69.3 7.5 3.2e-08 33.5 0.1 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAM17426.1 - 1.6e-09 37.9 2.5 0.00073 19.7 0.2 3.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM17426.1 - 4.9e-09 36.1 1.7 0.0013 18.7 0.0 4.1 3 2 0 3 3 3 3 Thioredoxin-like Thioredoxin_5 PF13743.1 GAM17426.1 - 0.0017 17.9 0.3 0.42 10.1 0.0 3.2 2 1 0 3 3 3 1 Thioredoxin Thioredoxin_7 PF13899.1 GAM17426.1 - 0.0018 18.2 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like ERp29_N PF07912.8 GAM17426.1 - 0.0066 16.3 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 ERp29, N-terminal domain Terpene_synth PF01397.16 GAM17426.1 - 0.024 14.0 1.1 3.2 7.0 0.2 2.2 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Tfb4 PF03850.9 GAM17426.1 - 0.035 13.3 0.5 0.072 12.3 0.2 1.6 1 1 1 2 2 2 0 Transcription factor Tfb4 DUF1764 PF08576.5 GAM17427.1 - 7.1e-19 68.4 5.0 7.1e-19 68.4 3.5 3.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) CDC27 PF09507.5 GAM17427.1 - 0.34 10.0 27.4 0.4 9.8 19.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MAGE_N PF12440.3 GAM17427.1 - 1.2 9.4 14.4 0.054 13.7 6.2 1.6 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal CytochromB561_N PF09786.4 GAM17427.1 - 1.9 6.8 15.0 2.3 6.5 10.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ycf1 PF05758.7 GAM17427.1 - 5.6 4.5 19.8 6.5 4.3 13.7 1.0 1 0 0 1 1 1 0 Ycf1 Glyco_hydro_15 PF00723.16 GAM17429.1 - 8.8e-37 126.7 0.0 2.1e-36 125.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF2372 PF10178.4 GAM17430.1 - 0.1 12.7 0.0 0.4 10.8 0.0 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) LRR_4 PF12799.2 GAM17430.1 - 0.13 11.9 7.0 0.39 10.4 0.0 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Mmp37 PF09139.6 GAM17431.1 - 1.3e-90 303.7 4.1 2.1e-90 303.1 2.8 1.3 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 DUF202 PF02656.10 GAM17432.1 - 4.2e-18 65.3 0.2 4.2e-18 65.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ATPase_gene1 PF09527.5 GAM17432.1 - 0.013 15.3 0.4 0.013 15.3 0.3 2.2 2 1 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) Pex14_N PF04695.8 GAM17432.1 - 0.018 15.0 1.7 0.027 14.4 1.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Calci_bind_CcbP PF11535.3 GAM17432.1 - 0.077 13.2 0.4 0.11 12.7 0.3 1.2 1 0 0 1 1 1 0 Calcium binding SdpI PF13630.1 GAM17432.1 - 0.37 10.5 6.2 4 7.2 0.4 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family GET2 PF08690.5 GAM17432.1 - 0.95 8.6 5.6 1.3 8.1 3.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4231 PF14015.1 GAM17432.1 - 4.7 7.2 5.8 38 4.3 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DP PF08781.5 GAM17433.1 - 2.4e-29 101.8 3.6 2.4e-29 101.8 2.5 2.0 2 0 0 2 2 2 1 Transcription factor DP E2F_TDP PF02319.15 GAM17433.1 - 2.9e-20 71.6 0.4 6.9e-20 70.3 0.3 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Mucin PF01456.12 GAM17433.1 - 0.056 13.2 15.5 0.13 12.0 10.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein LPP20 PF02169.11 GAM17433.1 - 0.24 11.5 9.3 0.59 10.2 0.4 3.6 3 0 0 3 3 3 0 LPP20 lipoprotein DNA_pol_B_2 PF03175.8 GAM17437.1 - 0.012 14.2 0.1 0.022 13.4 0.0 1.4 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral He_PIG PF05345.7 GAM17438.1 - 0.061 13.3 0.4 0.098 12.6 0.3 1.3 1 0 0 1 1 1 0 Putative Ig domain zf-CCHC PF00098.18 GAM17438.1 - 0.47 10.4 3.6 0.97 9.4 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_S49_N PF08496.5 GAM17438.1 - 1.1 9.0 5.1 1.4 8.6 3.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Mucin PF01456.12 GAM17440.1 - 0.0076 16.0 6.7 0.009 15.7 4.7 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.7 GAM17440.1 - 0.06 11.1 1.6 0.063 11.0 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAM17440.1 - 3.4 7.4 13.0 5.1 6.8 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 GAM17440.1 - 4.8 6.8 7.8 6.7 6.3 5.4 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.6 GAM17440.1 - 5 4.9 12.5 6.4 4.6 8.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 OMPdecase PF00215.19 GAM17443.1 - 3.5e-74 249.0 0.5 5.9e-74 248.2 0.3 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 GAM17443.1 - 2.6e-11 43.3 2.1 6e-11 42.1 0.6 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain GST_N_2 PF13409.1 GAM17444.1 - 1.6e-15 56.8 0.0 2.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM17444.1 - 2.8e-14 52.7 0.0 4.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM17444.1 - 2.9e-08 33.5 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM17444.1 - 5.6e-05 23.5 0.0 9.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM17444.1 - 0.0031 17.6 0.0 0.083 13.1 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Metallophos_C PF14008.1 GAM17445.1 - 2.6e-15 56.2 0.6 7.3e-14 51.6 0.3 2.7 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAM17445.1 - 1.1e-12 47.7 3.4 2.9e-12 46.4 2.3 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 GAM17445.1 - 0.014 13.9 2.1 1.6 7.2 0.5 2.5 2 1 0 2 2 2 0 PhoD-like phosphatase WD40 PF00400.27 GAM17446.1 - 7.9e-71 231.6 27.4 1.7e-08 34.0 0.1 11.6 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 GAM17446.1 - 1.5e-16 60.2 0.2 2.8e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 GAM17446.1 - 1e-05 24.4 10.5 0.005 15.6 1.2 4.8 2 2 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 GAM17446.1 - 8.3e-05 20.9 5.6 0.41 8.7 0.2 4.4 4 0 0 4 4 4 2 Nucleoporin Nup120/160 WRKY PF03106.10 GAM17447.1 - 1.5e-47 159.2 18.5 5.3e-25 87.0 4.9 3.2 2 1 1 3 3 3 2 WRKY DNA -binding domain TPR_11 PF13414.1 GAM17448.1 - 1.9e-17 62.6 14.6 4.3e-10 39.0 1.1 4.4 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 GAM17448.1 - 8.2e-14 50.3 14.7 0.00014 21.5 0.3 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM17448.1 - 2e-13 49.2 15.6 1.5e-05 24.4 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM17448.1 - 4.2e-12 45.8 11.2 6.4e-05 22.8 0.2 4.6 3 1 0 4 4 4 3 Tetratricopeptide repeat SET PF00856.23 GAM17448.1 - 1.4e-10 41.6 0.1 6.3e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 SET domain TPR_14 PF13428.1 GAM17448.1 - 1.5e-05 25.2 0.2 1.8 9.4 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat zf-MYND PF01753.13 GAM17448.1 - 2.4e-05 24.1 11.3 2.4e-05 24.1 7.8 3.5 3 1 0 3 3 1 1 MYND finger TPR_8 PF13181.1 GAM17448.1 - 0.00047 19.7 17.6 0.053 13.3 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM17448.1 - 0.0019 18.5 0.9 0.71 10.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM17448.1 - 0.0025 17.7 2.7 8.4 6.4 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM17448.1 - 0.0032 18.1 0.1 40 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17448.1 - 0.027 14.8 0.2 0.84 10.0 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM17448.1 - 0.072 12.9 0.1 2.3 8.1 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM17448.1 - 0.23 11.3 3.6 9.1 6.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat BAF1_ABF1 PF04684.8 GAM17448.1 - 6.2 5.5 29.1 12 4.5 20.2 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RasGAP PF00616.14 GAM17449.1 - 5.8e-20 71.7 0.5 1.5e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.13 GAM17449.1 - 2.3e-19 69.3 0.1 8.4e-19 67.5 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain WASH_WAHD PF11945.3 GAM17452.1 - 2e-46 158.6 2.5 3e-46 158.0 1.8 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Str_synth PF03088.11 GAM17453.1 - 2.7e-18 65.7 0.0 1.7e-17 63.1 0.0 2.4 3 1 0 3 3 3 1 Strictosidine synthase SGL PF08450.7 GAM17453.1 - 6.2e-16 58.5 0.0 4.1e-15 55.8 0.0 2.1 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 GAM17453.1 - 4.2e-06 26.4 4.3 0.017 15.0 0.0 5.0 5 0 0 5 5 5 2 NHL repeat Arylesterase PF01731.15 GAM17453.1 - 0.0012 18.8 0.0 0.0048 16.8 0.0 2.0 2 0 0 2 2 2 1 Arylesterase LSM PF01423.17 GAM17454.1 - 8.9e-13 47.5 0.2 1.4e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 LSM domain Coiled PF05710.7 GAM17455.1 - 3.3e-08 33.8 4.3 3.9e-08 33.6 3.0 1.1 1 0 0 1 1 1 1 Coiled coil Ribosomal_L37e PF01907.14 GAM17455.1 - 0.045 13.5 2.6 0.28 10.9 0.5 2.0 1 1 1 2 2 2 0 Ribosomal protein L37e INCENP_ARK-bind PF03941.10 GAM17456.1 - 0.33 10.8 3.8 0.78 9.6 2.6 1.6 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region RhoGAP PF00620.22 GAM17457.1 - 6.4e-47 158.9 0.1 1.2e-46 158.0 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 GAM17457.1 - 2e-39 134.8 3.2 4.6e-39 133.7 2.2 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 GAM17457.1 - 6.4e-12 45.2 1.3 1.6e-11 43.9 0.9 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain DUF2810 PF10928.3 GAM17457.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) zf-UBR PF02207.15 GAM17458.1 - 1.6e-18 66.1 11.5 3e-18 65.2 8.0 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PurA PF04845.8 GAM17459.1 - 0.059 12.4 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein FNIP PF05725.7 GAM17460.1 - 2.5e-80 264.1 5.0 4.1e-14 52.2 0.0 12.1 9 2 3 13 13 13 12 FNIP Repeat IPK PF03770.11 GAM17462.1 - 8.6e-49 165.8 0.2 1.1e-48 165.4 0.1 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase HCaRG PF07258.9 GAM17463.1 - 2.9e-35 121.3 0.5 3.5e-35 121.1 0.4 1.0 1 0 0 1 1 1 1 HCaRG protein FNIP PF05725.7 GAM17464.1 - 5.1e-09 35.9 12.3 7.9e-05 22.5 0.4 5.3 5 2 0 5 5 5 4 FNIP Repeat AmoC PF04896.7 GAM17466.1 - 0.0012 17.9 1.4 0.0021 17.1 0.6 1.4 1 1 0 1 1 1 1 Ammonia monooxygenase/methane monooxygenase, subunit C DUF1084 PF06454.6 GAM17466.1 - 0.032 13.2 4.6 0.15 11.0 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1084) Inhibitor_I29 PF08246.7 GAM17468.1 - 9.3e-10 38.6 0.0 2.6e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF4367 PF14285.1 GAM17468.1 - 0.01 15.1 1.1 0.013 14.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) CRAL_TRIO PF00650.15 GAM17469.1 - 1e-45 155.0 0.1 1.5e-45 154.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM17469.1 - 2.7e-11 43.4 1.3 6.5e-11 42.2 0.3 2.1 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM17469.1 - 2.1e-10 40.6 0.1 3.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LIM_bind PF01803.11 GAM17470.1 - 2.8e-29 101.9 0.0 2.8e-29 101.9 0.0 3.2 2 1 1 3 3 3 1 LIM-domain binding protein SeqA PF03925.8 GAM17470.1 - 0.017 14.8 0.1 0.017 14.8 0.1 2.4 2 0 0 2 2 2 0 SeqA protein DUF1266 PF06889.6 GAM17470.1 - 1.2 8.8 5.7 10 5.8 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) FimP PF09766.4 GAM17470.1 - 2.1 7.3 28.4 0.42 9.6 5.0 2.6 3 0 0 3 3 3 0 Fms-interacting protein Glt_symporter PF03616.9 GAM17470.1 - 3.2 6.1 4.3 1.8 6.9 0.0 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter DivIC PF04977.10 GAM17470.1 - 4.1 6.9 21.8 0.11 11.9 4.9 2.8 2 0 0 2 2 2 0 Septum formation initiator Suf PF05843.9 GAM17470.1 - 4.6 6.8 25.6 5.2 6.7 3.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spore_YhcN_YlaJ PF09580.5 GAM17470.1 - 5.9 6.9 17.8 4.2 7.4 2.5 2.4 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Met_synt_B12 PF02965.12 GAM17472.1 - 0.68 9.0 6.6 0.16 11.1 0.9 2.3 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Chlam_vir PF05475.6 GAM17472.1 - 0.89 8.6 3.9 1.2 8.1 1.0 2.2 2 0 0 2 2 2 0 Chlamydia virulence protein PGP3-D VPS9 PF02204.13 GAM17473.1 - 4.5e-21 74.8 2.2 8.8e-21 73.8 0.3 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain OKR_DC_1_N PF03709.10 GAM17473.1 - 0.066 13.2 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF4419 PF14388.1 GAM17474.1 - 9.2e-100 333.6 0.1 1.1e-99 333.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Metallophos_C PF14008.1 GAM17475.1 - 1e-15 57.5 0.2 1e-15 57.5 0.1 3.2 4 0 0 4 4 4 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAM17475.1 - 7.3e-15 54.8 5.1 1.7e-14 53.6 3.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2184 PF09950.4 GAM17475.1 - 0.039 12.9 0.0 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) Wzt_C PF14524.1 GAM17476.1 - 0.0032 17.1 0.2 0.0061 16.2 0.2 1.4 1 0 0 1 1 1 1 Wzt C-terminal domain DUF4469 PF14734.1 GAM17476.1 - 0.004 17.0 0.1 0.0095 15.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4469) with IG-like fold DUF1793 PF08760.6 GAM17476.1 - 0.039 13.8 0.3 0.088 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) RepA1_leader PF08048.7 GAM17476.1 - 2.2 8.4 5.8 8.3 6.5 1.4 2.4 2 0 0 2 2 2 0 Tap RepA1 leader peptide DUF4469 PF14734.1 GAM17479.1 - 0.00031 20.5 0.1 0.00066 19.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4469) with IG-like fold Wzt_C PF14524.1 GAM17479.1 - 0.02 14.6 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain EFG_C PF00679.19 GAM17479.1 - 0.04 13.7 0.1 0.079 12.8 0.0 1.6 1 1 0 1 1 1 0 Elongation factor G C-terminus Peptidase_S9_N PF02897.10 GAM17479.1 - 0.068 11.7 0.3 0.086 11.4 0.2 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4469 PF14734.1 GAM17480.1 - 0.0057 16.5 0.1 0.016 15.0 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4469) with IG-like fold Wzt_C PF14524.1 GAM17480.1 - 0.0073 15.9 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Wzt C-terminal domain DUF1793 PF08760.6 GAM17480.1 - 0.0097 15.7 0.2 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) TRAM_LAG1_CLN8 PF03798.11 GAM17481.1 - 6.3e-37 127.0 27.2 6.3e-37 127.0 18.8 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 GAM17481.1 - 0.31 10.5 5.5 0.29 10.6 1.2 2.7 2 1 0 2 2 2 0 TRAM1-like protein FNIP PF05725.7 GAM17482.1 - 5.2e-17 61.5 5.9 0.00013 21.8 0.0 5.3 4 2 2 6 6 6 5 FNIP Repeat SNARE PF05739.14 GAM17483.1 - 2.7e-16 59.0 6.3 2.7e-16 59.0 4.3 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 GAM17483.1 - 2.4e-08 34.0 3.3 2.4e-08 34.0 2.3 2.7 1 1 2 3 3 3 1 Syntaxin Tex_N PF09371.5 GAM17483.1 - 0.0028 16.9 7.4 0.0043 16.3 0.4 2.1 2 0 0 2 2 2 1 Tex-like protein N-terminal domain MCPsignal PF00015.16 GAM17483.1 - 0.003 17.1 1.3 0.003 17.1 0.9 1.9 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.1 GAM17483.1 - 0.013 15.5 3.5 0.013 15.5 2.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein ABC2_membrane_3 PF12698.2 GAM17483.1 - 0.019 13.9 2.6 0.025 13.6 1.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Laminin_II PF06009.7 GAM17483.1 - 0.45 10.2 6.8 1.3 8.7 0.7 2.3 2 0 0 2 2 2 0 Laminin Domain II IL3 PF02059.10 GAM17483.1 - 1 9.3 4.2 1.7 8.6 0.2 2.6 1 1 0 2 2 2 0 Interleukin-3 SUR7 PF06687.7 GAM17484.1 - 0.0023 17.5 1.3 0.0039 16.7 0.9 1.4 1 0 0 1 1 1 1 SUR7/PalI family Zip PF02535.17 GAM17484.1 - 0.07 12.1 2.0 0.11 11.5 1.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3124 PF11322.3 GAM17484.1 - 0.083 12.8 0.1 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) Claudin_2 PF13903.1 GAM17484.1 - 3 7.5 10.2 7.2 6.2 7.0 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PepSY_TM_2 PF13703.1 GAM17484.1 - 3.1 8.0 8.0 17 5.6 0.9 2.9 1 1 1 2 2 2 0 PepSY-associated TM helix Claudin_2 PF13903.1 GAM17485.1 - 3.8e-05 23.4 4.3 3.8e-05 23.4 3.0 2.0 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3068 PF11271.3 GAM17485.1 - 0.027 13.5 0.1 0.027 13.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3068) DUF4448 PF14610.1 GAM17485.1 - 0.032 13.7 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4064 PF13273.1 GAM17485.1 - 1.2 9.2 7.7 0.47 10.5 1.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.10 GAM17485.1 - 9.2 6.5 9.6 12 6.1 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Lipoprotein_15 PF03640.10 GAM17486.1 - 1.2e-47 159.1 1.0 1.8e-10 40.0 0.0 6.2 6 0 0 6 6 6 5 Secreted repeat of unknown function FTP PF07504.8 GAM17486.1 - 0.042 13.3 0.2 1.4 8.4 0.0 3.4 4 0 0 4 4 4 0 Fungalysin/Thermolysin Propeptide Motif Lum_binding PF00677.12 GAM17487.1 - 0.015 15.2 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Lumazine binding domain MARVEL PF01284.18 GAM17489.1 - 5.1 6.9 12.5 6.5 6.5 2.1 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF641 PF04859.7 GAM17490.1 - 0.09 12.5 14.1 0.14 11.9 2.2 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.1 GAM17490.1 - 0.11 11.4 7.9 0.1 11.5 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) L31 PF09784.4 GAM17490.1 - 2.1 8.4 8.5 0.42 10.7 0.8 3.0 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 A_deaminase PF00962.17 GAM17491.1 - 1.4e-110 369.3 0.2 1.9e-110 368.9 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MIP PF00230.15 GAM17492.1 - 2.7e-54 184.0 18.0 3.2e-54 183.7 12.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Sulfate_transp PF00916.15 GAM17493.1 - 1.4e-67 227.6 10.3 3.1e-67 226.5 7.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM17493.1 - 5.1e-27 93.3 3.1 5.1e-27 93.3 2.2 2.9 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM17493.1 - 2.9e-17 62.1 0.1 5.1e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain DUF1365 PF07103.6 GAM17494.1 - 4.1e-35 121.0 0.0 1.2e-34 119.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.15 GAM17494.1 - 1.6e-13 50.3 0.1 8e-10 38.2 0.0 2.8 3 0 0 3 3 3 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 GAM17494.1 - 0.00036 21.0 0.0 0.00073 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM17494.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.17 GAM17495.1 - 5.8e-23 80.3 0.1 3.7e-10 39.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17495.1 - 1.6e-17 63.1 0.1 1e-11 44.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17495.1 - 2.1e-13 50.0 0.1 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2951 PF11166.3 GAM17495.1 - 6.1 6.7 7.4 0.35 10.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) CBS PF00571.23 GAM17497.1 - 1.7e-25 88.4 4.1 6.1e-12 45.1 0.3 2.3 2 0 0 2 2 2 2 CBS domain DisA_N PF02457.11 GAM17497.1 - 0.053 12.6 0.1 0.1 11.7 0.1 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DEAD PF00270.24 GAM17498.1 - 1.6e-44 151.4 0.9 2.8e-41 140.8 0.1 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM17498.1 - 8.8e-26 89.5 0.9 1e-24 86.1 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM17498.1 - 0.0037 16.1 0.0 0.0087 14.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1477 PF07346.6 GAM17498.1 - 0.035 14.1 0.6 0.1 12.6 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) RNase_T PF00929.19 GAM17500.1 - 5.9e-25 88.4 0.0 1.5e-24 87.1 0.0 1.7 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 GAM17500.1 - 0.002 17.6 0.3 0.018 14.5 0.2 2.5 1 1 0 1 1 1 1 3'-5' exonuclease ORC6 PF05460.8 GAM17501.1 - 0.013 14.6 5.4 0.016 14.3 3.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Arena_glycoprot PF00798.13 GAM17501.1 - 0.042 12.2 0.2 0.046 12.1 0.2 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein TMEM154 PF15102.1 GAM17501.1 - 0.044 13.4 1.1 0.1 12.3 0.8 1.6 1 1 0 1 1 1 0 TMEM154 protein family HHV6-IE PF03753.8 GAM17501.1 - 0.056 10.9 6.0 0.063 10.7 4.2 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Dicty_REP PF05086.7 GAM17501.1 - 0.5 8.0 8.2 0.68 7.6 5.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DNA_pol_viral_N PF00242.12 GAM17501.1 - 0.54 9.2 10.1 0.73 8.8 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SR-25 PF10500.4 GAM17501.1 - 2 7.8 14.5 2.8 7.3 10.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MAP65_ASE1 PF03999.7 GAM17501.1 - 5.4 5.4 9.9 7 5.1 6.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) adh_short PF00106.20 GAM17502.1 - 9.8e-32 110.1 2.2 1.8e-31 109.2 1.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase SCP2 PF02036.12 GAM17502.1 - 1.1e-22 80.2 0.2 2.3e-22 79.1 0.2 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.5 GAM17502.1 - 1.3e-17 64.0 0.8 2.4e-17 63.1 0.5 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 GAM17502.1 - 0.00017 21.5 0.2 0.0003 20.7 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal RmlD_sub_bind PF04321.12 GAM17502.1 - 0.059 12.2 0.7 0.24 10.2 0.6 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain SeqA PF03925.8 GAM17503.1 - 0.013 15.2 0.7 0.027 14.1 0.5 1.5 1 0 0 1 1 1 0 SeqA protein Endonuc_Holl PF10107.4 GAM17503.1 - 0.068 12.8 0.2 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase GST_N_2 PF13409.1 GAM17504.1 - 3.9e-10 39.5 0.0 7.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM17504.1 - 5.4e-10 39.3 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM17504.1 - 1.9e-09 37.4 0.0 3.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM17504.1 - 1e-08 34.9 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM17504.1 - 3.2e-06 27.2 0.0 8.1e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM17504.1 - 0.00013 22.3 0.0 0.00021 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_28 PF02636.12 GAM17505.1 - 9.2e-69 231.6 0.0 1.3e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase rRNA_processing PF08524.6 GAM17505.1 - 0.24 11.1 2.8 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 rRNA processing PI31_Prot_N PF11566.3 GAM17506.1 - 1.3e-19 70.3 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 GAM17506.1 - 8.3e-10 39.1 16.5 8.3e-10 39.1 11.5 2.7 3 0 0 3 3 3 1 PI31 proteasome regulator PALP PF00291.20 GAM17507.1 - 4.4e-60 203.5 0.1 7.5e-60 202.7 0.1 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 GAM17507.1 - 1.9e-14 53.1 0.0 4.3e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 CBS domain HAD PF12710.2 GAM17507.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4449 PF14613.1 GAM17508.1 - 4.2e-07 30.0 0.6 8.3e-07 29.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) Ank_2 PF12796.2 GAM17509.1 - 0.0089 16.3 0.1 0.52 10.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) RasGAP PF00616.14 GAM17511.1 - 4.6e-44 150.4 0.1 1.1e-43 149.2 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.9 GAM17511.1 - 2.1e-18 66.3 0.0 9.6e-18 64.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Bromodomain PF00439.20 GAM17512.1 - 2.7e-22 78.4 3.8 4.7e-22 77.7 0.2 2.6 2 1 0 2 2 2 1 Bromodomain DUF4618 PF15397.1 GAM17512.1 - 0.0029 16.9 0.5 0.23 10.7 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Phasin PF05597.6 GAM17512.1 - 0.023 14.4 0.2 0.071 12.8 0.1 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Syntaxin-6_N PF09177.6 GAM17512.1 - 0.11 12.8 0.5 0.11 12.8 0.3 2.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 GAM17512.1 - 0.18 11.3 2.0 0.55 9.7 0.6 2.2 2 1 0 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 GAM17512.1 - 3.4 7.7 11.3 0.32 11.0 3.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family GATase_2 PF00310.16 GAM17513.1 - 1.7e-18 66.5 0.0 8.2e-14 51.0 0.0 2.8 2 1 1 3 3 3 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 GAM17513.1 - 5.5e-16 58.4 0.0 9.6e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 GAM17513.1 - 3.9e-12 45.9 0.0 6.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAM17513.1 - 4e-12 46.2 0.0 8.9e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 GAM17513.1 - 0.0016 17.1 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 GAM17513.1 - 0.12 11.6 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase DUF619 PF04768.8 GAM17514.1 - 6.2e-34 116.8 0.0 1.5e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 GAM17514.1 - 0.00051 19.6 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 Amino acid kinase family RNA_pol_3_Rpc31 PF11705.3 GAM17514.1 - 0.48 10.3 12.4 0.97 9.3 8.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.1 GAM17515.1 - 0.011 16.0 1.2 0.011 16.0 0.8 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_D PF01813.12 GAM17515.1 - 0.13 11.8 2.3 0.72 9.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase subunit D Macoilin PF09726.4 GAM17515.1 - 0.19 9.9 23.1 0.23 9.6 16.0 1.2 1 0 0 1 1 1 0 Transmembrane protein RCR PF12273.3 GAM17515.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.7 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ndc1_Nup PF09531.5 GAM17515.1 - 3.2 6.0 14.5 4.2 5.6 10.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YL1 PF05764.8 GAM17515.1 - 5 6.6 27.8 1.9 8.0 3.5 2.1 1 1 1 2 2 2 0 YL1 nuclear protein MAPKK1_Int PF08923.5 GAM17516.1 - 3.6e-30 104.0 0.3 4.1e-30 103.8 0.2 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting RWP-RK PF02042.10 GAM17518.1 - 1.2e-25 89.0 0.1 2.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HlyIII PF03006.15 GAM17519.1 - 2.5e-55 187.3 18.7 3.4e-55 186.8 12.9 1.2 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 GAM17519.1 - 0.00089 19.1 0.0 0.0058 16.4 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF962) Ceramidase PF05875.7 GAM17519.1 - 0.047 12.8 17.2 21 4.0 11.9 2.2 1 1 0 1 1 1 0 Ceramidase Hat1_N PF10394.4 GAM17520.1 - 1.1e-39 136.1 1.5 1.1e-39 136.1 1.1 2.0 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 GAM17520.1 - 0.00021 21.3 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 GAM17520.1 - 0.0012 18.1 0.4 0.0029 16.8 0.3 1.7 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 GAM17520.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM17520.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mec-17 PF05301.6 GAM17520.1 - 0.068 13.1 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 RasGEF PF00617.14 GAM17522.1 - 2e-57 193.9 0.9 5.1e-57 192.6 0.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM17522.1 - 8.5e-23 80.4 0.6 6.7e-22 77.5 0.4 2.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_S24e PF01282.14 GAM17523.1 - 2.7e-29 100.7 0.5 5.8e-29 99.7 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S24e PCI_Csn8 PF10075.4 GAM17524.1 - 7.5e-27 93.8 0.0 1.1e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PTEN_C2 PF10409.4 GAM17525.1 - 2e-18 66.4 0.0 3.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 GAM17525.1 - 1.9e-10 40.4 0.0 3.6e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM17525.1 - 4.7e-07 29.3 0.0 2.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM17525.1 - 0.0066 16.7 0.1 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family SR-25 PF10500.4 GAM17526.1 - 0.00097 18.6 13.5 0.00097 18.6 9.3 3.6 2 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein Daxx PF03344.10 GAM17526.1 - 0.17 10.3 29.9 0.33 9.3 11.5 2.1 2 0 0 2 2 2 0 Daxx Family BTV_NS2 PF04514.7 GAM17526.1 - 1.1 8.0 19.7 0.41 9.4 3.6 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 YaaC PF14175.1 GAM17526.1 - 1.4 7.8 11.4 4.2 6.2 6.7 2.0 2 0 0 2 2 2 0 YaaC-like Protein MIP-T3 PF10243.4 GAM17526.1 - 3.8 5.8 43.7 0.017 13.5 10.4 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Methyltransf_12 PF08242.7 GAM17526.1 - 3.8 8.0 7.8 14 6.2 0.9 2.6 2 0 0 2 2 2 0 Methyltransferase domain Utp14 PF04615.8 GAM17526.1 - 6.6 4.7 30.2 3 5.8 8.9 2.1 2 0 0 2 2 2 0 Utp14 protein DUF572 PF04502.8 GAM17526.1 - 7.2 5.7 29.8 1.6 7.8 6.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Frizzled PF01534.12 GAM17527.1 - 5.7e-09 35.2 14.0 7.8e-09 34.7 9.7 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 GAM17527.1 - 0.002 18.4 4.0 0.0039 17.5 2.8 1.6 1 0 0 1 1 1 1 Fz domain TMA7 PF09072.5 GAM17527.1 - 3.4 8.2 3.6 6.2 7.3 2.5 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 Acyl-CoA_dh_1 PF00441.19 GAM17528.1 - 3.4e-26 92.1 0.8 5.8e-26 91.3 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM17528.1 - 7.3e-21 74.8 0.0 1.5e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM17528.1 - 9.6e-14 50.6 0.0 1.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM17528.1 - 8.9e-10 38.9 0.0 2.1e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TyeA PF09059.5 GAM17528.1 - 0.013 15.3 0.0 0.059 13.2 0.0 2.1 2 0 0 2 2 2 0 TyeA Methyltransf_8 PF05148.10 GAM17529.1 - 4.3e-80 268.4 1.8 6.5e-80 267.8 1.2 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 GAM17529.1 - 2.7e-08 34.1 0.2 2.7e-08 34.1 0.2 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM17529.1 - 0.00011 21.8 2.6 0.0091 15.5 0.3 2.8 2 1 1 3 3 3 2 Methyltransferase domain MTS PF05175.9 GAM17529.1 - 0.00014 21.3 0.5 0.0033 16.8 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 GAM17529.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 GAM17529.1 - 0.068 12.8 0.2 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain FAM60A PF15396.1 GAM17529.1 - 1.1 8.9 8.4 2.1 8.0 5.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A WD40 PF00400.27 GAM17530.1 - 1e-45 152.0 18.3 4.4e-09 35.8 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 GAM17530.1 - 1.8e-11 43.5 0.1 4.3e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 GAM17530.1 - 4.1e-06 25.2 21.3 0.18 9.8 2.4 5.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 GAM17530.1 - 1.4e-05 24.5 0.0 3.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain FNIP PF05725.7 GAM17531.1 - 7.5e-27 93.0 6.4 6.6e-10 38.7 0.0 8.1 6 2 2 8 8 8 6 FNIP Repeat BRCA-2_OB3 PF09104.5 GAM17531.1 - 0.08 12.7 0.1 0.31 10.8 0.0 1.9 1 1 1 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 LRR_7 PF13504.1 GAM17531.1 - 0.33 11.3 11.3 18 6.0 0.0 7.3 7 1 0 7 7 7 0 Leucine rich repeat FNIP PF05725.7 GAM17532.1 - 9.6e-19 67.0 26.9 3.7e-12 45.9 0.2 6.0 3 2 0 4 4 4 3 FNIP Repeat LRR_7 PF13504.1 GAM17532.1 - 4.6 7.8 15.0 76 4.2 0.0 6.7 7 0 0 7 7 7 0 Leucine rich repeat PP_kinase_C PF13090.1 GAM17533.1 - 6.9e-133 442.6 0.2 9.6e-133 442.1 0.2 1.2 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain PP_kinase PF02503.12 GAM17533.1 - 1.2e-59 201.3 0.2 8.7e-59 198.4 0.2 2.1 2 0 0 2 2 2 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.1 GAM17533.1 - 5.2e-17 61.9 0.7 1.4e-16 60.4 0.5 1.8 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.1 GAM17533.1 - 1.8e-12 47.1 0.2 1.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Bmp PF02608.9 GAM17533.1 - 0.062 12.0 0.4 0.13 11.0 0.3 1.4 1 0 0 1 1 1 0 Basic membrane protein FNIP PF05725.7 GAM17534.1 - 2.3e-23 81.8 6.2 2.3e-10 40.2 0.0 6.7 5 1 1 6 6 6 5 FNIP Repeat DUF1769 PF08588.5 GAM17534.1 - 0.0033 17.3 0.5 5.9 6.9 0.0 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1769) LRR_7 PF13504.1 GAM17534.1 - 0.29 11.5 6.4 39 5.0 0.0 5.6 7 0 0 7 7 7 0 Leucine rich repeat FNIP PF05725.7 GAM17535.1 - 5.1e-28 96.7 26.6 1.2e-11 44.3 0.7 7.5 6 3 3 9 9 9 6 FNIP Repeat WD40 PF00400.27 GAM17536.1 - 3.9e-11 42.3 8.4 2.1e-06 27.4 0.1 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat FNIP PF05725.7 GAM17537.1 - 3.5e-17 62.0 18.2 2.8e-06 27.1 0.0 7.6 6 2 2 8 8 8 7 FNIP Repeat FNIP PF05725.7 GAM17538.1 - 5.4e-13 48.6 19.6 3e-05 23.8 0.0 7.3 6 2 0 8 8 8 5 FNIP Repeat DUF3184 PF11380.3 GAM17539.1 - 9.7e-07 27.1 0.5 0.00018 19.6 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3184) FNIP PF05725.7 GAM17540.1 - 8.6e-28 96.0 8.0 6.7e-10 38.7 0.3 7.5 5 2 2 7 7 7 5 FNIP Repeat GED PF02212.13 GAM17540.1 - 0.11 12.4 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Dynamin GTPase effector domain Ras PF00071.17 GAM17541.1 - 3.3e-58 195.6 0.0 3.8e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17541.1 - 1e-19 71.2 0.0 1.6e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17541.1 - 9.9e-09 34.6 0.0 1.1e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM17541.1 - 2.9e-06 26.8 0.1 2.2e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM17541.1 - 0.00026 20.9 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM17541.1 - 0.02 14.4 0.6 0.26 10.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 GAM17541.1 - 0.038 13.2 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 GAM17541.1 - 0.052 12.5 0.0 0.092 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_25 PF13481.1 GAM17541.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAM17541.1 - 0.078 12.1 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2647 PF10839.3 GAM17541.1 - 0.088 12.8 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) FNIP PF05725.7 GAM17542.1 - 2.7e-07 30.4 6.5 0.014 15.3 0.0 6.1 4 2 1 6 6 6 3 FNIP Repeat Ras PF00071.17 GAM17543.1 - 5.6e-57 191.6 0.0 6.5e-57 191.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17543.1 - 2.7e-18 66.6 0.0 4.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17543.1 - 5.3e-08 32.2 0.0 5.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM17543.1 - 1.7e-05 24.3 0.0 0.0001 21.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM17543.1 - 0.00077 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM17543.1 - 0.0063 16.0 0.2 0.17 11.3 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 GAM17543.1 - 0.033 13.5 0.1 0.048 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 GAM17543.1 - 0.04 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FeoB_N PF02421.13 GAM17543.1 - 0.062 12.5 0.0 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 GAM17543.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 GAM17543.1 - 0.094 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TPR_12 PF13424.1 GAM17544.1 - 0.03 14.2 0.3 0.14 12.1 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM17544.1 - 0.049 13.2 0.2 0.17 11.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM17544.1 - 0.16 11.8 4.6 4.5 7.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.11 GAM17544.1 - 1.9 8.5 7.4 4.6 7.2 1.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 zf-CCCH PF00642.19 GAM17545.1 - 2.3e-09 36.7 19.9 0.00031 20.3 2.6 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SAM_1 PF00536.25 GAM17545.1 - 9.2e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM17545.1 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ndc1_Nup PF09531.5 GAM17545.1 - 3.9 5.7 7.2 5.3 5.3 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CCCH_2 PF14608.1 GAM17545.1 - 9.8 6.3 18.9 6.9 6.8 1.4 3.8 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type SAM_1 PF00536.25 GAM17546.1 - 5.5e-08 32.8 0.0 8.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM17546.1 - 2.3e-07 30.5 0.0 4.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CagA PF03507.8 GAM17546.1 - 0.0057 16.5 0.2 0.008 16.0 0.1 1.2 1 0 0 1 1 1 1 CagA exotoxin SbcD_C PF12320.3 GAM17546.1 - 0.13 12.3 1.7 0.36 10.8 0.1 2.2 2 1 1 3 3 3 0 Type 5 capsule protein repressor C-terminal domain UPF0697 PF15117.1 GAM17546.1 - 0.4 10.4 2.9 0.76 9.5 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 PAT1 PF09770.4 GAM17546.1 - 2.9 6.0 17.8 3 5.9 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCCH PF00642.19 GAM17547.1 - 1.1e-11 44.1 22.4 0.00048 19.7 3.1 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAM17547.1 - 0.00099 19.0 0.7 0.00099 19.0 0.5 4.6 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type Nop14 PF04147.7 GAM17547.1 - 0.34 8.7 6.4 0.35 8.7 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 GAM17547.1 - 0.69 8.9 5.8 1.1 8.2 4.0 1.3 1 0 0 1 1 1 0 BUD22 DUF3295 PF11702.3 GAM17547.1 - 0.74 8.7 4.8 0.98 8.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) zf-CCCH PF00642.19 GAM17548.1 - 4.2e-21 74.1 46.5 0.00039 20.0 3.0 6.2 6 0 0 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SAM_1 PF00536.25 GAM17548.1 - 3.4e-07 30.3 0.2 5.7e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM17548.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRV_FeS PF05484.6 GAM17548.1 - 0.0021 17.5 14.7 0.52 9.9 0.3 4.8 5 0 0 5 5 5 3 LRV protein FeS4 cluster SAM_PNT PF02198.11 GAM17548.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain ubiquitin PF00240.18 GAM17549.1 - 2e-168 546.0 31.0 2.4e-33 113.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 GAM17549.1 - 5.9e-95 311.0 26.9 2e-18 65.8 0.4 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM17549.1 - 5.2e-29 100.3 14.9 0.0003 20.9 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAM17549.1 - 6.1e-16 58.2 4.1 0.3 10.9 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM17549.1 - 1.2e-15 57.4 2.1 0.42 10.8 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM17549.1 - 3.1e-13 49.5 0.0 2 8.4 0.0 5.7 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 GAM17549.1 - 6.5e-08 32.3 7.7 6.3 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 GAM17549.1 - 7.4e-08 31.7 2.2 2.4 7.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Big_3_3 PF13750.1 GAM17549.1 - 1.4e-07 31.1 0.1 16 4.8 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Corona_NS2A PF05213.7 GAM17549.1 - 1.2e-06 28.0 0.0 21 4.3 0.0 5.0 1 1 1 5 5 5 0 Coronavirus NS2A protein IGR PF09597.5 GAM17549.1 - 2e-06 27.5 0.1 45 4.0 0.0 5.3 5 0 0 5 5 5 0 IGR protein motif DUF3435 PF11917.3 GAM17549.1 - 0.00014 20.7 1.1 31 3.1 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3435) Plexin_cytopl PF08337.7 GAM17549.1 - 0.00057 18.3 14.6 6 5.0 0.1 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 GAM17549.1 - 0.001 18.7 7.3 51 3.7 0.0 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain ACT_4 PF13291.1 GAM17549.1 - 0.0013 19.0 0.2 2.1e+02 2.3 0.0 5.0 5 0 0 5 5 5 0 ACT domain DUF3642 PF12182.3 GAM17549.1 - 0.0018 18.6 10.6 52 4.3 0.0 5.4 5 0 0 5 5 5 0 Bacterial lipoprotein GABP-alpha PF11620.3 GAM17549.1 - 0.039 13.9 8.6 90 3.1 0.0 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain DUF3781 PF12636.2 GAM17549.1 - 0.18 11.7 8.5 1.5e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) FNIP PF05725.7 GAM17550.1 - 7.9e-18 64.1 12.8 3.6e-08 33.2 0.1 6.1 5 1 0 5 5 5 3 FNIP Repeat FNIP PF05725.7 GAM17551.1 - 1.6e-22 79.1 11.9 5.5e-09 35.8 0.1 6.1 4 2 2 6 6 6 5 FNIP Repeat ThiF PF00899.16 GAM17552.1 - 2.7e-28 98.4 0.0 5.1e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 GAM17552.1 - 0.0012 18.8 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 GAM17552.1 - 0.035 13.2 0.0 0.96 8.5 0.0 2.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ubiquitin PF00240.18 GAM17553.1 - 4.1e-05 22.8 8.0 0.00055 19.2 0.1 5.1 4 0 0 4 4 4 2 Ubiquitin family NT-C2 PF10358.4 GAM17554.1 - 9.3e-09 34.9 7.4 6.5e-08 32.1 5.0 2.5 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF912 PF06024.7 GAM17554.1 - 0.52 10.3 4.1 0.21 11.6 0.2 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3987 PF13148.1 GAM17554.1 - 1.4 7.3 11.4 2.8 6.4 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) IncA PF04156.9 GAM17554.1 - 4 6.9 33.4 9.4 5.7 15.2 2.2 1 1 1 2 2 2 0 IncA protein Drf_FH3 PF06367.11 GAM17554.1 - 7.4 5.9 18.0 0.72 9.2 5.2 2.3 2 0 0 2 2 2 0 Diaphanous FH3 Domain BRCT PF00533.21 GAM17555.1 - 3e-34 116.9 17.8 2.2e-08 34.1 0.0 8.2 10 1 0 10 10 10 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM17555.1 - 8.3e-30 102.4 0.3 7.4e-15 54.5 0.0 5.6 5 0 0 5 5 5 4 twin BRCT domain LRR_6 PF13516.1 GAM17556.1 - 6.1e-12 44.3 6.7 0.00056 19.6 0.1 4.8 4 1 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.28 GAM17556.1 - 0.33 11.1 6.1 6.9 7.1 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 GAM17556.1 - 3.7 7.2 16.4 0.064 12.8 3.1 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Thr_synth_N PF14821.1 GAM17558.1 - 5e-27 93.7 0.0 1.3e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 GAM17558.1 - 2.3e-19 69.7 0.0 3.5e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KLRAQ PF10205.4 GAM17559.1 - 1.2e-14 54.2 11.9 1.2e-14 54.2 8.2 4.9 2 2 3 5 5 5 1 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.4 GAM17559.1 - 1.1e-07 31.2 1.6 1.1e-07 31.2 1.1 3.3 3 1 0 3 3 3 1 Predicted coiled-coil domain-containing protein MerR PF00376.18 GAM17559.1 - 0.19 11.3 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein RabGAP-TBC PF00566.13 GAM17560.1 - 2.9e-38 131.4 10.7 3.8e-38 131.1 7.4 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC50_N PF15295.1 GAM17560.1 - 0.0084 16.0 8.3 0.015 15.2 5.8 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus Rxt3 PF08642.5 GAM17560.1 - 0.027 14.6 0.2 0.053 13.7 0.2 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 RNA_pol_Rpb1_5 PF04998.12 GAM17560.1 - 0.28 10.3 3.9 0.41 9.8 2.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SSP160 PF06933.6 GAM17561.1 - 0.005 14.9 11.1 0.0077 14.2 7.7 1.4 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 GAM17561.1 - 0.81 7.3 5.8 1.2 6.8 4.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1510 PF07423.6 GAM17562.1 - 0.00062 19.2 6.7 0.00062 19.2 4.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1510) Ion_trans PF00520.26 GAM17562.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Ion transport protein Tetraspannin PF00335.15 GAM17562.1 - 0.41 9.8 1.3 0.62 9.3 0.9 1.3 1 0 0 1 1 1 0 Tetraspanin family TBCC PF07986.7 GAM17563.1 - 1.6e-08 33.9 0.7 1.6e-08 33.9 0.5 1.9 2 0 0 2 2 2 1 Tubulin binding cofactor C DUF4108 PF13390.1 GAM17563.1 - 0.029 14.0 0.4 0.069 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) TMPIT PF07851.8 GAM17563.1 - 4.3 6.3 8.1 5.9 5.8 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4203 PF13886.1 GAM17564.1 - 3e-06 26.8 22.7 3.9e-06 26.4 15.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Rifin_STEVOR PF02009.11 GAM17565.1 - 0.0016 18.1 0.9 0.0029 17.3 0.7 1.4 1 0 0 1 1 1 1 Rifin/stevor family SOG2 PF10428.4 GAM17565.1 - 0.088 11.4 14.3 0.1 11.2 9.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.6 GAM17565.1 - 0.32 10.1 2.5 0.51 9.4 1.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NMD3 PF04981.8 GAM17566.1 - 2.4e-75 252.7 5.6 3.6e-75 252.0 3.9 1.3 1 0 0 1 1 1 1 NMD3 family DUF1289 PF06945.8 GAM17566.1 - 0.055 12.9 2.0 2.6 7.5 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF1032 PF06278.6 GAM17567.1 - 1.2e-54 185.8 21.7 6.1e-33 114.1 3.8 4.4 3 1 0 3 3 3 2 Protein of unknown function (DUF1032) ScpA_ScpB PF02616.9 GAM17567.1 - 0.026 14.1 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 0 ScpA/B protein Rootletin PF15035.1 GAM17568.1 - 0.00064 19.7 2.5 0.00075 19.5 1.7 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 GAM17568.1 - 0.00077 19.1 3.3 0.0011 18.7 2.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 GAM17568.1 - 0.00078 19.3 8.0 0.0011 18.9 5.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 GAM17568.1 - 0.00091 19.1 2.9 0.0011 18.8 2.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Muted PF14942.1 GAM17568.1 - 0.0035 17.2 1.7 0.006 16.4 1.2 1.4 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein TMCO5 PF14992.1 GAM17568.1 - 0.031 13.4 4.5 0.036 13.2 3.1 1.1 1 0 0 1 1 1 0 TMCO5 family GCOM2 PF15328.1 GAM17568.1 - 0.087 12.5 4.5 0.2 11.3 3.1 1.6 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 FAM60A PF15396.1 GAM17568.1 - 0.14 11.9 0.8 0.18 11.5 0.2 1.4 1 1 0 1 1 1 0 Protein Family FAM60A DUF342 PF03961.8 GAM17568.1 - 0.14 10.5 3.3 0.14 10.4 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SPT16 PF08644.6 GAM17568.1 - 0.15 11.9 1.7 0.69 9.7 1.2 1.9 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) bZIP_1 PF00170.16 GAM17568.1 - 0.3 11.0 5.5 3.3 7.7 1.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor OmpH PF03938.9 GAM17568.1 - 7 6.5 8.5 17 5.2 5.8 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FNIP PF05725.7 GAM17569.1 - 3.2e-64 212.6 19.0 2e-12 46.8 0.4 6.4 4 1 2 6 6 6 6 FNIP Repeat LRR_5 PF13306.1 GAM17569.1 - 9.9e-10 38.2 0.0 0.00021 21.0 0.0 2.7 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) WD40 PF00400.27 GAM17570.1 - 1.4e-18 66.0 8.4 9.9e-08 31.5 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM17570.1 - 1.9e-06 27.5 0.1 5e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain FimP PF09766.4 GAM17570.1 - 0.021 13.9 5.4 0.032 13.3 3.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein Cytochrom_D1 PF02239.11 GAM17570.1 - 0.023 12.9 0.8 1.9 6.7 0.1 3.0 2 1 2 4 4 4 0 Cytochrome D1 heme domain WD40 PF00400.27 GAM17571.1 - 4.9e-15 54.7 6.9 2.5e-08 33.4 0.3 4.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Ycf1 PF05758.7 GAM17571.1 - 0.0023 15.7 3.0 0.003 15.3 2.1 1.1 1 0 0 1 1 1 1 Ycf1 Hid1 PF12722.2 GAM17571.1 - 0.01 13.5 4.9 0.013 13.2 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PQQ_3 PF13570.1 GAM17571.1 - 0.17 12.2 0.0 0.96 9.8 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain Hid1 PF12722.2 GAM17572.1 - 0.0025 15.6 4.7 0.0028 15.4 3.3 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Daxx PF03344.10 GAM17572.1 - 0.17 10.3 28.4 0.21 10.0 19.7 1.0 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 GAM17572.1 - 0.17 10.4 5.9 0.18 10.4 4.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 GAM17572.1 - 0.29 8.7 8.9 0.31 8.7 6.2 1.0 1 0 0 1 1 1 0 Ycf1 VID27 PF08553.5 GAM17572.1 - 0.43 8.7 18.1 0.47 8.6 12.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 GAM17572.1 - 0.64 9.3 18.4 0.89 8.8 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 GAM17572.1 - 2.1 7.7 13.9 3.1 7.2 9.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 GAM17572.1 - 2.8 6.9 25.9 4.3 6.2 17.9 1.2 1 0 0 1 1 1 0 BUD22 Astro_capsid PF03115.9 GAM17572.1 - 3.3 5.8 11.2 4.1 5.5 7.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SDA1 PF05285.7 GAM17572.1 - 7.5 5.7 27.8 9.5 5.3 19.3 1.1 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.20 GAM17573.1 - 2.8e-16 59.4 0.1 4.8e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17573.1 - 4.4e-12 45.6 0.0 9.9e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TIG PF01833.19 GAM17575.1 - 3.5e-19 68.5 72.0 7.7e-10 38.6 2.1 8.5 7 2 1 8 8 8 6 IPT/TIG domain EGF PF00008.22 GAM17575.1 - 0.0061 16.5 6.8 0.015 15.2 4.7 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.8 GAM17575.1 - 0.04 14.0 11.4 0.094 12.9 7.9 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.19 GAM17575.1 - 0.9 9.5 6.9 2.9 7.8 4.8 1.8 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Peptidase_C1 PF00112.18 GAM17576.1 - 3.2e-75 252.7 5.7 3.2e-75 252.7 4.0 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM17576.1 - 7e-16 58.2 9.8 1.5e-15 57.1 6.8 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Nsp3_PL2pro PF12124.3 GAM17576.1 - 0.024 14.1 0.2 0.55 9.8 0.1 2.7 1 1 0 1 1 1 0 Coronavirus polyprotein cleavage domain His_Phos_2 PF00328.17 GAM17578.1 - 2e-28 99.7 0.2 2.8e-28 99.2 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ion_trans PF00520.26 GAM17579.1 - 2.6e-07 30.1 8.5 3.2e-07 29.8 2.8 2.0 2 0 0 2 2 2 1 Ion transport protein COX15-CtaA PF02628.10 GAM17579.1 - 0.14 10.9 3.5 0.19 10.5 0.1 2.0 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein DUF588 PF04535.7 GAM17579.1 - 0.88 9.1 5.2 0.25 10.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF588) YlaC PF10777.4 GAM17579.1 - 2.4 7.7 7.6 0.72 9.3 3.1 1.7 1 1 0 1 1 1 0 Inner membrane protein YlaC Hum_adeno_E3A PF05393.6 GAM17579.1 - 4 7.1 7.8 2.8 7.6 2.2 2.6 1 1 2 3 3 3 0 Human adenovirus early E3A glycoprotein Rhomboid PF01694.17 GAM17580.1 - 7.1e-21 74.7 10.6 1.5e-20 73.7 7.4 1.5 1 0 0 1 1 1 1 Rhomboid family MORN PF02493.15 GAM17580.1 - 0.0023 17.5 2.7 0.036 13.7 0.3 2.9 2 0 0 2 2 2 1 MORN repeat SR-25 PF10500.4 GAM17580.1 - 0.027 13.9 4.8 0.04 13.3 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pneumo_phosprot PF02478.11 GAM17580.1 - 0.3 10.5 1.9 0.43 10.0 1.3 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF3185 PF11381.3 GAM17580.1 - 0.59 9.9 7.5 1.6 8.5 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) bZIP_C PF12498.3 GAM17580.1 - 0.62 11.3 7.3 7.1 7.9 5.4 2.2 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Avl9 PF09794.4 GAM17581.1 - 5.5e-55 186.3 3.0 1.1e-54 185.3 2.1 1.6 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 GAM17581.1 - 0.00013 21.6 0.5 0.062 13.0 0.1 2.9 1 1 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 GAM17581.1 - 0.00023 20.5 1.0 0.00051 19.4 0.7 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 GAM17581.1 - 0.012 15.3 0.5 0.034 13.8 0.2 1.9 2 0 0 2 2 2 0 DENN (AEX-3) domain Dynamin_N PF00350.18 GAM17581.1 - 0.035 13.9 0.4 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Pribosyltran PF00156.22 GAM17582.1 - 4.4e-17 61.9 0.0 5.6e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM17582.1 - 0.028 13.6 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Dus PF01207.12 GAM17583.1 - 5.5e-50 169.9 0.0 6.6e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Aldolase_II PF00596.16 GAM17584.1 - 1.3e-40 138.9 0.0 1.7e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PcfK PF14058.1 GAM17584.1 - 0.15 12.1 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 PcfK-like protein FAA_hydrolase PF01557.13 GAM17586.1 - 2.6e-50 170.9 0.0 4.1e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 GAM17586.1 - 2.3e-33 114.3 0.0 6.8e-33 112.8 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal bZIP_2 PF07716.10 GAM17587.1 - 3e-08 33.3 8.8 3e-08 33.3 6.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM17587.1 - 7e-06 25.9 3.7 7e-06 25.9 2.5 2.3 2 0 0 2 2 2 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 GAM17587.1 - 0.035 13.9 0.1 0.035 13.9 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein TSC22 PF01166.13 GAM17587.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family Vps23_core PF09454.5 GAM17589.1 - 4.3e-26 90.3 0.8 7.6e-26 89.5 0.5 1.4 1 0 0 1 1 1 1 Vps23 core domain UEV PF05743.8 GAM17589.1 - 7.7e-24 83.6 0.1 1.5e-23 82.7 0.1 1.5 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.21 GAM17589.1 - 0.0055 16.1 0.5 0.014 14.8 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM17589.1 - 0.021 14.5 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Mod_r PF07200.8 GAM17589.1 - 0.11 12.4 11.8 0.094 12.6 1.6 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein THOC7 PF05615.8 GAM17589.1 - 0.25 11.6 7.8 0.065 13.5 0.9 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 APG6 PF04111.7 GAM17589.1 - 0.83 8.6 13.3 1.1 8.1 4.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 GAM17589.1 - 2.3 7.9 13.3 0.078 12.7 2.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Choline_transpo PF04515.7 GAM17590.1 - 1.6e-57 194.7 40.5 2.8e-57 193.9 23.8 2.6 2 1 0 2 2 2 2 Plasma-membrane choline transporter WASH_WAHD PF11945.3 GAM17591.1 - 8.4e-56 189.4 0.2 1e-55 189.1 0.1 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.15 GAM17591.1 - 1.7e-05 24.2 0.1 3.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 WH2 motif Effector_1 PF04518.7 GAM17591.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Baculo_PEP_C PF04513.7 GAM17591.1 - 0.14 11.9 0.5 0.29 10.9 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cpn60_TCP1 PF00118.19 GAM17592.1 - 2.6e-143 478.1 15.2 2.9e-143 478.0 10.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2 PF00152.15 GAM17593.1 - 1.8e-74 250.4 0.0 2.6e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.10 GAM17593.1 - 9.3e-42 142.3 0.0 1.6e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.20 GAM17593.1 - 7.4e-13 48.1 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_synt_1c_R2 PF04557.10 GAM17593.1 - 0.0019 18.8 5.4 0.0038 17.8 3.8 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF3656 PF12392.3 GAM17593.1 - 0.0039 17.2 0.6 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Collagenase HCaRG PF07258.9 GAM17594.1 - 3.2e-35 121.2 0.5 3.7e-35 121.0 0.3 1.0 1 0 0 1 1 1 1 HCaRG protein SAP PF02037.22 GAM17595.1 - 4.6e-07 29.1 0.0 1.5e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 SAP domain VRR_NUC PF08774.6 GAM17595.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 VRR-NUC domain FNIP PF05725.7 GAM17596.1 - 6.9e-11 41.9 7.4 2e-06 27.6 0.0 5.8 4 2 1 5 5 5 4 FNIP Repeat Med15_fungi PF05397.7 GAM17598.1 - 0.04 13.9 1.7 0.053 13.5 0.3 1.9 2 1 0 2 2 2 0 Mediator complex subunit 15 DUF2935 PF11155.3 GAM17598.1 - 0.094 12.8 2.1 0.27 11.3 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) RVT_1 PF00078.22 GAM17600.1 - 5.9e-14 51.9 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MAP65_ASE1 PF03999.7 GAM17600.1 - 6.1 5.3 10.9 8.6 4.8 7.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Prenyltrans PF00432.16 GAM17601.1 - 2.9e-42 141.8 4.0 1.2e-10 40.8 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM17601.1 - 2.7e-40 137.2 0.0 3.8e-14 53.0 0.0 5.2 4 1 2 6 6 6 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM17601.1 - 2.4e-30 104.7 0.0 1.2e-12 47.8 0.0 5.9 4 1 3 7 7 7 6 Prenyltransferase-like Pec_lyase PF09492.5 GAM17601.1 - 4.7e-10 39.1 0.1 0.029 13.5 0.0 5.3 4 2 2 6 6 6 4 Pectic acid lyase A2M_comp PF07678.9 GAM17601.1 - 0.002 17.4 0.3 9.3 5.4 0.0 4.5 4 1 1 5 5 5 1 A-macroglobulin complement component ABC2_membrane PF01061.19 GAM17602.1 - 3.8e-32 111.1 26.1 3.8e-32 111.1 18.1 1.5 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM17602.1 - 1.5e-27 96.5 0.0 3.9e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM17602.1 - 2e-12 47.6 0.0 3.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAM17602.1 - 1.6e-05 24.1 0.0 0.066 12.2 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 GAM17602.1 - 7.4e-05 22.2 0.0 0.008 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM17602.1 - 0.00018 22.2 0.0 0.00035 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM17602.1 - 0.00026 21.1 0.0 0.001 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM17602.1 - 0.00035 19.5 0.2 0.00063 18.7 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.14 GAM17602.1 - 0.00089 18.5 0.1 0.36 10.0 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM17602.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 GAM17602.1 - 0.00099 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM17602.1 - 0.0024 17.0 0.1 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM17602.1 - 0.0026 17.2 0.1 0.0061 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 GAM17602.1 - 0.0051 16.5 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 GAM17602.1 - 0.0054 16.6 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 GAM17602.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAM17602.1 - 0.015 15.2 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM17602.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM17602.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 GAM17602.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 GAM17602.1 - 0.023 14.6 0.8 0.24 11.3 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RecA PF00154.16 GAM17602.1 - 0.028 13.4 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA PF00004.24 GAM17602.1 - 0.029 14.5 0.0 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 GAM17602.1 - 0.029 13.8 0.1 0.065 12.6 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 GAM17602.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 GAM17602.1 - 0.18 11.3 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain vWA-TerF-like PF10138.4 GAM17603.1 - 4.6e-13 49.4 0.0 6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 GAM17603.1 - 1.8e-10 41.1 0.1 2.4e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM17603.1 - 8.2e-10 38.6 0.1 1.1e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 GAM17603.1 - 4.3e-08 32.9 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 GAM17603.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein ATP-sulfurylase PF01747.12 GAM17604.1 - 8.5e-82 273.6 0.0 1.1e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 GAM17604.1 - 2.8e-59 199.2 0.0 5.2e-59 198.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 GAM17604.1 - 2.6e-48 163.4 0.0 3.8e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.1 GAM17604.1 - 3e-05 24.3 0.1 6.5e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM17604.1 - 3.5e-05 23.2 0.0 7.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM17604.1 - 6.6e-05 23.7 0.0 0.0002 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 GAM17604.1 - 0.00027 20.2 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 GAM17604.1 - 0.00054 19.8 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM17604.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 GAM17604.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 GAM17604.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 GAM17604.1 - 0.03 13.7 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 GAM17604.1 - 0.037 13.2 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 GAM17604.1 - 0.045 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 GAM17604.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 GAM17604.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.7 GAM17604.1 - 0.098 12.2 0.1 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 GAM17604.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM17604.1 - 0.16 12.2 0.1 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 GAM17604.1 - 0.23 10.2 0.0 0.36 9.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 GAM17604.1 - 0.26 10.8 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PTEN_C2 PF10409.4 GAM17605.1 - 5.6e-18 64.9 3.2 1.3e-16 60.5 2.2 2.3 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 GAM17605.1 - 1.1e-06 28.3 0.7 2.7e-06 27.0 0.0 2.0 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM17605.1 - 1.4e-06 28.3 0.3 4.6e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 GAM17605.1 - 1.4e-05 24.5 0.6 3.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM17605.1 - 1.6e-05 25.2 0.8 3.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family CDKN3 PF05706.7 GAM17605.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 GAM17605.1 - 0.031 13.6 0.0 0.084 12.2 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family TFIIE_alpha PF02002.12 GAM17606.1 - 1.1e-13 50.5 1.2 3.4e-13 49.0 0.9 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.15 GAM17606.1 - 0.027 14.5 0.6 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator Zn-ribbon_8 PF09723.5 GAM17606.1 - 0.065 13.1 0.6 0.16 11.9 0.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain RXT2_N PF08595.6 GAM17606.1 - 0.079 12.7 2.4 0.21 11.3 1.7 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DDE_3 PF13358.1 GAM17607.1 - 7.3e-20 71.1 0.0 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.12 GAM17607.1 - 0.08 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Codanin-1_C PF15296.1 GAM17607.1 - 0.11 12.3 0.2 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Codanin-1 C-terminus Ribosomal_S14 PF00253.16 GAM17608.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e BCNT PF07572.7 GAM17608.1 - 0.42 10.5 9.1 2.3 8.2 0.3 3.4 3 0 0 3 3 3 0 Bucentaur or craniofacial development Abhydrolase_2 PF02230.11 GAM17609.1 - 8.6e-63 211.6 0.2 9.5e-63 211.5 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM17609.1 - 2.3e-13 50.1 0.0 3.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM17609.1 - 2.4e-08 34.1 0.0 2.6e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM17609.1 - 5e-06 25.8 0.2 0.00016 21.0 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 GAM17609.1 - 2e-05 24.1 0.0 4.6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 GAM17609.1 - 0.00033 20.2 0.2 0.28 10.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 GAM17609.1 - 0.019 14.5 0.0 0.08 12.5 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.17 GAM17609.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.6 2 0 0 2 2 2 0 Cutinase Esterase PF00756.15 GAM17609.1 - 0.075 12.4 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.23 GAM17610.1 - 3.5e-13 49.1 0.6 6e-13 48.3 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM17610.1 - 2e-11 43.8 0.1 3.6e-11 43.0 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM17610.1 - 3.5e-10 39.8 0.0 4.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 GAM17610.1 - 5.7e-06 25.4 0.6 8.6e-06 24.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 GAM17610.1 - 1.8e-05 24.1 0.2 2.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 GAM17610.1 - 3e-05 23.0 0.2 4.5e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 GAM17610.1 - 0.00019 21.3 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM17610.1 - 0.00054 19.5 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 GAM17610.1 - 0.00057 19.3 1.3 0.0018 17.7 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 GAM17610.1 - 0.0041 16.7 1.5 0.0089 15.6 1.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 GAM17610.1 - 0.014 14.5 0.1 0.033 13.2 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.6 GAM17610.1 - 0.084 12.5 0.1 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Tubulin PF00091.20 GAM17611.1 - 2.9e-69 233.1 0.0 4.5e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM17611.1 - 4.3e-44 149.5 0.4 6.6e-44 148.9 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAM17611.1 - 2.5e-05 23.8 0.0 0.00021 20.7 0.0 2.4 2 1 1 3 3 3 1 Tubulin domain Rotamase PF00639.16 GAM17612.1 - 5e-26 91.2 0.0 1e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 GAM17612.1 - 3e-20 72.6 0.1 5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain FHA PF00498.21 GAM17612.1 - 3.9e-19 68.5 0.4 2.3e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 FHA domain Rotamase_2 PF13145.1 GAM17612.1 - 0.002 18.7 0.0 0.0042 17.7 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain IncA PF04156.9 GAM17612.1 - 0.32 10.5 2.8 0.5 9.9 1.9 1.2 1 0 0 1 1 1 0 IncA protein Sec5 PF15469.1 GAM17613.1 - 3.3e-46 157.2 2.9 4.2e-46 156.9 0.2 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 GAM17613.1 - 0.00064 19.5 0.1 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 FHA PF00498.21 GAM17614.1 - 2.3e-21 75.7 0.0 5.8e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain DPBB_1 PF03330.13 GAM17615.1 - 3e-05 23.9 0.1 6.9e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 GAM17616.1 - 0.012 15.6 0.1 0.044 13.7 0.1 2.0 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SET PF00856.23 GAM17617.1 - 2.8e-17 63.4 0.4 1.2e-16 61.4 0.3 2.0 1 1 0 1 1 1 1 SET domain HTH_Tnp_Tc5 PF03221.11 GAM17618.1 - 1.9e-10 40.3 0.1 3.3e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_29 PF13551.1 GAM17618.1 - 0.0058 16.7 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Sec10 PF07393.6 GAM17619.1 - 5.5e-09 34.7 3.0 9e-09 34.0 2.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec10 Sec6 PF06046.8 GAM17619.1 - 4.8e-07 28.2 1.6 4.8e-07 28.2 1.1 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 COG4 PF08318.7 GAM17619.1 - 9.9e-06 24.5 0.8 9.9e-06 24.5 0.6 2.2 2 1 0 2 2 2 1 COG4 transport protein DIL PF01843.14 GAM17619.1 - 0.00064 19.5 2.0 0.002 17.9 1.4 1.8 1 0 0 1 1 1 1 DIL domain DNA_Packaging PF11053.3 GAM17619.1 - 0.0076 15.8 0.1 0.022 14.3 0.1 1.8 1 0 0 1 1 1 1 Terminase DNA packaging enzyme DNA_pol3_delt_C PF14840.1 GAM17619.1 - 0.27 11.3 3.0 0.48 10.5 0.3 2.5 2 1 1 3 3 3 0 Processivity clamp loader gamma complex DNA pol III C-term PHO4 PF01384.15 GAM17621.1 - 3.3e-102 341.4 16.8 3.9e-102 341.2 11.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Lectin_legB PF00139.14 GAM17622.1 - 6.2e-19 68.2 0.4 1e-18 67.6 0.0 1.5 2 0 0 2 2 2 1 Legume lectin domain C9orf72-like PF15019.1 GAM17623.1 - 3.4e-36 124.6 3.2 3.4e-36 124.6 2.2 2.2 3 0 0 3 3 3 1 C9orf72-like protein family HSP20 PF00011.16 GAM17624.1 - 1.5e-23 82.5 1.1 2e-23 82.1 0.8 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 GAM17624.1 - 0.0024 18.3 1.3 0.0065 16.9 0.7 1.9 1 1 1 2 2 2 1 CS domain DUF4097 PF13349.1 GAM17624.1 - 0.036 13.6 1.8 0.045 13.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) DUF2807 PF10988.3 GAM17624.1 - 0.28 10.6 3.5 0.6 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) AAA_2 PF07724.9 GAM17625.1 - 1e-49 168.7 0.0 2.5e-48 164.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 GAM17625.1 - 1.3e-26 92.2 2.3 1.6e-26 91.9 0.2 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 GAM17625.1 - 1.2e-23 83.7 0.3 4.9e-13 49.4 0.0 3.1 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM17625.1 - 7.6e-16 58.1 0.0 6.8e-10 38.8 0.0 3.2 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM17625.1 - 3.9e-13 49.7 0.3 4.4e-05 23.5 0.0 4.7 3 1 1 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 GAM17625.1 - 6e-11 42.6 4.4 2.1e-05 24.6 0.0 4.7 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 GAM17625.1 - 4.5e-07 29.5 0.0 0.00023 20.6 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 GAM17625.1 - 2.5e-06 27.4 0.0 0.05 13.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 GAM17625.1 - 7e-06 25.9 7.0 0.34 10.5 0.0 4.7 4 1 1 5 5 5 2 Archaeal ATPase Mg_chelatase PF01078.16 GAM17625.1 - 8.4e-06 25.0 0.0 0.19 10.8 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM17625.1 - 9.1e-06 25.2 0.0 0.071 12.5 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 GAM17625.1 - 6.2e-05 23.3 1.2 0.094 13.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAM17625.1 - 6.6e-05 23.7 1.0 0.65 10.8 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 GAM17625.1 - 7.9e-05 23.0 5.8 0.13 12.5 3.6 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 GAM17625.1 - 0.00015 21.8 0.1 2.3 8.4 0.0 3.9 4 0 0 4 4 3 2 RNA helicase RuvB_N PF05496.7 GAM17625.1 - 0.00043 19.4 0.9 0.39 9.7 0.0 3.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 GAM17625.1 - 0.00092 18.6 0.1 0.51 9.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 GAM17625.1 - 0.0013 18.4 0.0 0.19 11.4 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain NACHT PF05729.7 GAM17625.1 - 0.0018 17.9 0.0 0.29 10.7 0.0 3.1 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 GAM17625.1 - 0.0035 17.2 0.0 0.16 11.8 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM17625.1 - 0.0044 16.2 0.1 1.6 7.8 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 GAM17625.1 - 0.0065 15.5 0.0 0.68 8.9 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.12 GAM17625.1 - 0.0086 15.6 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 GAM17625.1 - 0.0089 16.3 0.7 6.1 7.1 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_28 PF13521.1 GAM17625.1 - 0.0097 15.8 0.0 3.3 7.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 GAM17625.1 - 0.0097 15.6 0.0 1.2 8.8 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 GAM17625.1 - 0.014 14.3 0.3 1.1 8.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 GAM17625.1 - 0.017 14.7 0.0 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM17625.1 - 0.019 14.6 0.0 17 5.0 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 GAM17625.1 - 0.022 14.6 0.0 5.1 6.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.1 GAM17625.1 - 0.026 14.0 0.0 6.1 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.17 GAM17625.1 - 0.029 13.8 0.0 3.6 6.9 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_3 PF07726.6 GAM17625.1 - 0.03 13.9 0.0 19 4.8 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 GAM17625.1 - 0.047 13.5 1.0 6 6.6 0.0 3.5 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 GAM17625.1 - 0.053 12.9 0.3 1.7 8.0 0.0 3.1 2 2 1 3 3 3 0 AAA-like domain Miro PF08477.8 GAM17625.1 - 0.066 13.7 0.0 1.3 9.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein IncA PF04156.9 GAM17625.1 - 4.3 6.8 11.7 0.91 9.0 5.3 2.0 2 0 0 2 2 2 0 IncA protein SpoIIE PF07228.7 GAM17626.1 - 1.5e-11 44.3 0.0 3.1e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 GAM17626.1 - 1.6e-06 27.6 0.0 1.6e-06 27.6 0.0 3.1 4 0 0 4 4 4 1 Protein phosphatase 2C PP2C PF00481.16 GAM17626.1 - 2.4e-05 23.8 3.8 0.082 12.2 0.0 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C PPR_2 PF13041.1 GAM17626.1 - 0.14 12.1 3.7 0.68 9.9 0.0 3.6 2 1 2 4 4 4 0 PPR repeat family DUF3446 PF11928.3 GAM17626.1 - 6.7 6.9 32.8 7.2 6.8 4.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) DUF2145 PF09916.4 GAM17627.1 - 0.091 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Dna2 PF08696.6 GAM17628.1 - 2.5e-58 196.8 0.4 5.4e-58 195.7 0.3 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 GAM17628.1 - 1.8e-51 174.4 0.0 4.1e-51 173.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM17628.1 - 2.4e-32 112.3 0.3 2.5e-19 69.8 0.0 4.0 4 1 1 5 5 5 2 AAA domain AAA_30 PF13604.1 GAM17628.1 - 1.9e-10 40.6 0.0 4.5e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM17628.1 - 8.2e-07 28.6 0.2 2.2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 GAM17628.1 - 3.3e-06 26.7 0.3 0.095 12.1 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.2 GAM17628.1 - 0.00022 20.6 0.0 0.0024 17.3 0.0 2.2 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_16 PF13191.1 GAM17628.1 - 0.002 18.1 0.0 0.0057 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 GAM17628.1 - 0.0027 17.3 0.0 0.014 15.0 0.0 2.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 GAM17628.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CbiA PF01656.18 GAM17628.1 - 0.03 13.7 0.0 0.086 12.2 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Mg_chelatase PF01078.16 GAM17628.1 - 0.084 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MgsA_C PF12002.3 GAM17629.1 - 4.3e-57 192.4 0.0 9.7e-57 191.3 0.0 1.6 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 GAM17629.1 - 2.1e-17 63.5 0.0 4.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM17629.1 - 5.4e-16 58.3 0.0 1.2e-13 50.6 0.0 2.2 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAM17629.1 - 1.4e-07 31.3 0.1 1.5e-06 28.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAM17629.1 - 5.4e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM17629.1 - 6.5e-06 26.2 0.2 0.00045 20.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 GAM17629.1 - 1.1e-05 25.0 0.0 0.00053 19.5 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAM17629.1 - 6.1e-05 22.2 0.1 0.15 11.2 0.0 2.8 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 GAM17629.1 - 0.00013 22.1 0.4 0.003 17.6 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAM17629.1 - 0.00036 20.5 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 GAM17629.1 - 0.00049 20.8 0.0 0.00092 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM17629.1 - 0.00071 19.4 0.0 0.0019 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM17629.1 - 0.00081 19.7 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 GAM17629.1 - 0.0031 17.5 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 1 1 Sigma-54 interaction domain zf-Di19 PF05605.7 GAM17629.1 - 0.005 16.9 0.7 0.015 15.4 0.5 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zeta_toxin PF06414.7 GAM17629.1 - 0.0078 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 GAM17629.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 GAM17629.1 - 0.018 13.7 0.0 0.064 11.9 0.0 1.8 1 1 1 2 2 2 0 TIP49 C-terminus ResIII PF04851.10 GAM17629.1 - 0.02 14.7 5.3 2.5 7.9 0.0 3.7 2 2 2 4 4 4 0 Type III restriction enzyme, res subunit DUF815 PF05673.8 GAM17629.1 - 0.027 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 GAM17629.1 - 0.036 13.4 0.0 0.078 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 GAM17629.1 - 0.045 12.6 0.0 0.16 10.7 0.0 1.7 1 1 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 GAM17629.1 - 0.076 12.5 0.0 0.076 12.5 0.0 2.5 2 1 1 3 3 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 GAM17629.1 - 0.096 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 GAM17629.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 GAM17629.1 - 0.14 11.7 0.0 1 9.0 0.0 2.0 1 1 0 2 2 2 0 Archaeal ATPase Eapp_C PF10238.4 GAM17629.1 - 0.98 9.3 14.9 0.059 13.2 2.7 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein PRELI PF04707.9 GAM17630.1 - 7.7e-48 162.0 0.0 1.1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family Ribosomal_L17 PF01196.14 GAM17630.1 - 0.012 16.1 0.4 0.023 15.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L17 SbcD_C PF12320.3 GAM17630.1 - 0.076 13.0 0.5 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain HD_3 PF13023.1 GAM17632.1 - 9e-43 145.8 0.0 1e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 GAM17632.1 - 2.4e-06 27.5 0.0 6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 HD domain SWIRM PF04433.12 GAM17633.1 - 9.9e-12 44.8 0.0 2.6e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAM17633.1 - 2.2e-10 40.3 0.0 7.1e-09 35.5 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 GAM17633.1 - 1.7e-09 37.0 5.2 3.7e-09 35.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 GAM17633.1 - 0.0016 18.5 0.0 0.0046 17.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mucin PF01456.12 GAM17635.1 - 0.00079 19.2 36.5 0.00079 19.2 25.3 3.4 1 1 1 2 2 2 1 Mucin-like glycoprotein Hemerythrin PF01814.18 GAM17636.1 - 1.3e-11 44.7 11.5 9.3e-10 38.7 2.4 1.9 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain ECIST_Cterm PF14784.1 GAM17636.1 - 0.023 14.6 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein WD40 PF00400.27 GAM17637.1 - 2.5e-56 185.6 19.1 6.1e-12 44.9 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 GAM17637.1 - 1.5e-09 36.5 0.4 0.029 12.5 0.0 3.4 2 2 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.6 GAM17637.1 - 9.4e-07 28.7 0.5 0.0046 16.6 0.0 3.2 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 GAM17637.1 - 0.00017 21.1 0.3 0.003 17.0 0.2 2.6 1 1 1 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 GAM17637.1 - 0.04 14.1 9.0 2.3 8.6 0.0 4.9 5 1 0 5 5 5 0 PQQ-like domain RNA_pol_3_Rpc31 PF11705.3 GAM17637.1 - 0.24 11.3 12.2 0.32 10.9 8.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2890 PF11081.3 GAM17637.1 - 0.72 9.8 6.3 1.3 9.0 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2457 PF10446.4 GAM17637.1 - 5.6 5.5 17.4 8.6 4.9 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kelch_6 PF13964.1 GAM17638.1 - 4.9e-13 48.6 7.3 4.6e-06 26.5 0.0 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM17638.1 - 8.3e-13 47.8 2.0 2.4e-07 30.4 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM17638.1 - 8.6e-09 35.3 1.8 9.9e-06 25.5 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM17638.1 - 4.2e-08 32.6 1.3 0.00029 20.3 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM17638.1 - 5.1e-07 29.2 0.2 0.97 9.3 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 GAM17638.1 - 0.03 14.2 5.1 0.68 9.9 0.2 2.6 2 0 0 2 2 2 0 Kelch motif zf-B_box PF00643.19 GAM17638.1 - 0.28 11.1 3.0 0.68 9.8 0.4 2.2 2 0 0 2 2 2 0 B-box zinc finger Kelch_6 PF13964.1 GAM17639.1 - 3.9e-18 64.7 5.3 2.3e-05 24.3 0.1 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM17639.1 - 3.7e-13 48.7 3.8 0.0015 18.0 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM17639.1 - 2.4e-11 43.2 3.4 0.0091 15.7 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.19 GAM17639.1 - 5.7e-09 35.7 4.3 1.6e-08 34.3 3.0 1.7 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.1 GAM17639.1 - 1.4e-06 28.1 3.2 0.19 11.7 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM17639.1 - 1.7e-05 24.3 6.9 1.3 8.9 0.1 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM17639.1 - 1.9e-05 24.6 5.4 0.035 14.2 0.0 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain zf-UBR PF02207.15 GAM17639.1 - 0.11 12.2 2.6 0.31 10.7 1.8 1.8 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) CRAL_TRIO PF00650.15 GAM17640.1 - 8e-36 122.9 0.1 1.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM17640.1 - 5.2e-11 42.5 0.9 1e-10 41.5 0.6 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM17640.1 - 4.1e-07 30.0 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-Tim10_DDP PF02953.10 GAM17640.1 - 0.029 13.6 0.9 0.56 9.5 0.1 2.3 2 0 0 2 2 2 0 Tim10/DDP family zinc finger GATA PF00320.22 GAM17641.1 - 3.9e-16 58.1 5.0 7.8e-16 57.1 3.5 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 GAM17641.1 - 0.015 15.2 1.3 0.032 14.2 0.9 1.5 1 0 0 1 1 1 0 zinc-finger DZR PF12773.2 GAM17641.1 - 0.096 12.5 1.0 0.21 11.4 0.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Pkinase_Tyr PF07714.12 GAM17642.1 - 7.4e-53 179.2 0.0 1.5e-52 178.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM17642.1 - 1.1e-47 162.3 0.0 2.4e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Miro PF08477.8 GAM17642.1 - 3.9e-19 69.3 1.8 3.6e-17 62.9 0.0 3.8 3 0 0 3 3 3 1 Miro-like protein LRR_4 PF12799.2 GAM17642.1 - 1.9e-14 52.9 16.3 2.9e-09 36.3 1.4 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Ras PF00071.17 GAM17642.1 - 2.1e-14 53.2 0.4 6.4e-14 51.6 0.3 1.9 1 0 0 1 1 1 1 Ras family LRR_8 PF13855.1 GAM17642.1 - 1.8e-10 40.4 3.2 2.4e-08 33.5 1.2 3.0 1 1 1 2 2 2 2 Leucine rich repeat Arf PF00025.16 GAM17642.1 - 4.2e-10 39.1 0.9 2.3e-09 36.7 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family LRR_1 PF00560.28 GAM17642.1 - 1.3e-07 30.6 4.8 0.03 14.3 0.0 4.8 4 0 0 4 4 3 3 Leucine Rich Repeat ABC_tran PF00005.22 GAM17642.1 - 0.00015 22.0 0.1 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 GAM17642.1 - 0.00033 19.8 1.0 0.0031 16.6 0.0 3.0 4 0 0 4 4 4 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM17642.1 - 0.00034 20.5 0.0 0.0014 18.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRR_7 PF13504.1 GAM17642.1 - 0.00045 19.9 3.3 0.18 12.0 0.0 4.5 4 0 0 4 4 3 1 Leucine rich repeat DUF258 PF03193.11 GAM17642.1 - 0.0022 17.1 0.5 0.017 14.2 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 LRR_6 PF13516.1 GAM17642.1 - 0.0035 17.2 1.0 0.55 10.4 0.0 4.0 2 1 1 3 3 3 1 Leucine Rich repeat FeoB_N PF02421.13 GAM17642.1 - 0.0047 16.2 0.2 0.033 13.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.4 GAM17642.1 - 0.015 14.7 1.8 0.03 13.7 0.6 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3611 PF12263.3 GAM17643.1 - 0.039 13.3 0.0 0.039 13.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) Tic20 PF09685.5 GAM17643.1 - 0.077 12.9 0.9 0.15 12.0 0.4 1.7 2 0 0 2 2 2 0 Tic20-like protein UPF0104 PF03706.8 GAM17643.1 - 0.12 11.6 4.4 0.18 11.0 3.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) AA_permease_2 PF13520.1 GAM17643.1 - 1.1 7.7 7.6 7.5 4.9 0.9 1.9 1 1 1 2 2 2 0 Amino acid permease DUF1049 PF06305.6 GAM17643.1 - 1.2 8.6 8.1 0.36 10.3 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) WD40 PF00400.27 GAM17644.1 - 7.3e-26 89.0 5.5 3.1e-07 30.0 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat BBE PF08031.7 GAM17645.1 - 3e-15 55.8 2.8 6.9e-15 54.6 1.9 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 GAM17646.1 - 5.9e-25 87.3 0.7 7.8e-25 86.9 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Asp_protease_2 PF13650.1 GAM17646.1 - 0.12 12.8 1.1 3.4 8.2 0.2 2.9 2 1 1 3 3 3 0 Aspartyl protease SK_channel PF03530.9 GAM17648.1 - 0.0045 16.7 3.8 0.0045 16.7 2.6 2.4 2 1 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.11 GAM17648.1 - 0.019 14.6 6.3 0.078 12.7 4.3 2.0 1 1 0 1 1 1 0 Ion channel DUF4395 PF14340.1 GAM17648.1 - 0.028 14.4 3.9 1.5 8.9 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) Totivirus_coat PF05518.6 GAM17648.1 - 0.45 8.2 3.2 0.69 7.6 2.3 1.3 1 0 0 1 1 1 0 Totivirus coat protein AAA_23 PF13476.1 GAM17648.1 - 5.5 7.2 11.1 9.4 6.4 7.7 1.3 1 0 0 1 1 1 0 AAA domain SNAP PF14938.1 GAM17649.1 - 3e-110 367.8 15.5 3.4e-110 367.6 10.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 GAM17649.1 - 7.4e-11 41.8 17.1 3.7e-06 26.7 1.9 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM17649.1 - 3.2e-07 30.8 11.2 0.075 13.7 0.8 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM17649.1 - 3.8e-07 29.4 11.2 0.014 15.1 0.1 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM17649.1 - 4.8e-07 29.3 15.7 0.00074 19.1 1.8 3.9 2 2 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 GAM17649.1 - 2.9e-06 26.7 23.0 0.48 10.4 0.1 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17649.1 - 1.2e-05 25.5 15.4 0.24 11.7 1.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM17649.1 - 8.7e-05 22.7 22.1 0.54 10.8 0.2 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM17649.1 - 0.00037 20.0 24.2 0.057 13.2 0.1 6.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM17649.1 - 0.00042 19.7 22.5 0.38 10.4 0.3 6.4 6 1 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM17649.1 - 0.00049 20.1 14.2 0.061 13.4 0.5 3.5 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Spatacsin_C PF14649.1 GAM17649.1 - 0.00075 18.4 6.5 0.0015 17.4 0.3 2.5 1 1 0 2 2 2 1 Spatacsin C-terminus RPN7 PF10602.4 GAM17649.1 - 0.00085 18.7 1.2 0.00085 18.7 0.8 2.4 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 GAM17649.1 - 0.0015 19.0 11.9 1.5 9.6 0.2 5.3 4 1 1 6 6 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM17649.1 - 0.0035 16.5 2.3 3.8 6.8 0.0 3.7 3 0 0 3 3 3 2 SHNi-TPR TPR_10 PF13374.1 GAM17649.1 - 0.0042 16.9 4.6 1.2 9.1 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 GAM17649.1 - 0.086 12.2 9.0 0.25 10.7 1.4 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Foie-gras_1 PF11817.3 GAM17649.1 - 0.99 8.8 7.1 2.2 7.7 4.9 1.6 1 1 0 1 1 1 0 Foie gras liver health family 1 CBS PF00571.23 GAM17650.1 - 3.4e-35 119.5 2.1 7.3e-09 35.2 0.1 4.3 4 0 0 4 4 4 4 CBS domain GDE_N PF12439.3 GAM17651.1 - 2.4 7.3 10.7 3.5 6.7 7.4 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal SKG6 PF08693.5 GAM17652.1 - 0.0021 17.3 0.1 0.0044 16.3 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Chlam_PMP PF02415.12 GAM17652.1 - 0.2 11.9 50.4 0.11 12.8 1.0 9.0 9 0 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat FimP PF09766.4 GAM17653.1 - 0.011 14.8 13.9 0.025 13.6 9.6 1.6 1 0 0 1 1 1 0 Fms-interacting protein DUF2185 PF09951.4 GAM17654.1 - 8.2e-28 96.0 0.1 2.7e-27 94.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) DUF2314 PF10077.4 GAM17654.1 - 3e-05 24.0 0.1 8.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2314) Period_C PF12114.3 GAM17654.1 - 0.0014 18.3 7.3 0.0026 17.4 5.1 1.4 1 0 0 1 1 1 1 Period protein 2/3C-terminal region Mem_trans PF03547.13 GAM17654.1 - 0.03 12.6 4.9 0.041 12.1 3.4 1.1 1 0 0 1 1 1 0 Membrane transport protein MDFI PF15316.1 GAM17654.1 - 2.3 8.2 5.8 3.6 7.5 4.0 1.2 1 0 0 1 1 1 0 MyoD family inhibitor TILa PF12714.2 GAM17655.1 - 0.75 9.6 27.5 0.21 11.3 1.1 4.1 2 2 2 4 4 4 0 TILa domain FNIP PF05725.7 GAM17656.1 - 1.9e-26 91.7 2.0 1.4e-11 44.1 0.0 4.5 2 1 1 4 4 4 4 FNIP Repeat Rad60-SLD PF11976.3 GAM17657.1 - 8.9e-12 44.5 0.0 9.9e-12 44.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM17657.1 - 1e-07 31.2 0.0 1.1e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM17658.1 - 7.2e-15 54.4 0.0 8e-15 54.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM17658.1 - 0.00018 20.8 0.0 0.00022 20.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family RecO_N_2 PF13114.1 GAM17658.1 - 0.057 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 RecO N terminal MMR_HSR1 PF01926.18 GAM17659.1 - 5.7e-18 64.9 0.0 1.5e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM17659.1 - 4.1e-10 39.1 0.0 6.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM17659.1 - 3.8e-08 32.9 0.6 3.8e-05 23.2 0.2 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAM17659.1 - 3.7e-07 30.1 0.7 0.00052 19.8 0.1 3.2 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 GAM17659.1 - 1.8e-05 24.0 0.0 4.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 GAM17659.1 - 0.00016 20.8 1.0 0.00066 18.8 0.1 2.2 2 1 0 2 2 2 1 AIG1 family Septin PF00735.13 GAM17659.1 - 0.0054 15.7 4.1 0.056 12.4 0.0 2.8 3 0 0 3 3 3 1 Septin PduV-EutP PF10662.4 GAM17659.1 - 0.0091 15.4 0.4 0.72 9.3 0.0 2.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAM17659.1 - 0.013 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAM17659.1 - 0.014 15.6 0.1 0.048 13.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Arf PF00025.16 GAM17659.1 - 0.015 14.5 0.4 1.3 8.2 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 GAM17659.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 GAM17659.1 - 0.099 13.1 0.7 0.41 11.1 0.0 2.5 2 1 1 3 3 3 0 Miro-like protein AAA_29 PF13555.1 GAM17659.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain VASP_tetra PF08776.6 GAM17659.1 - 0.19 11.0 5.7 0.16 11.2 2.2 2.3 2 0 0 2 2 2 0 VASP tetramerisation domain DUF382 PF04037.8 GAM17659.1 - 2.2 8.1 6.2 7 6.4 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF382) ABC_membrane PF00664.18 GAM17660.1 - 9.5e-47 159.6 11.0 1.5e-46 159.0 7.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAM17660.1 - 5e-36 124.0 0.0 1.2e-35 122.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 GAM17660.1 - 1.4e-06 27.7 0.0 2.9e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM17660.1 - 0.00037 21.3 0.0 0.00079 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 GAM17660.1 - 0.00089 19.3 0.1 0.49 10.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 GAM17660.1 - 0.0015 18.6 0.1 0.012 15.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM17660.1 - 0.0049 16.3 0.1 0.13 11.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM17660.1 - 0.0049 17.0 0.0 0.034 14.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 GAM17660.1 - 0.0085 15.6 0.0 0.03 13.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM17660.1 - 0.01 15.7 0.1 0.034 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 GAM17660.1 - 0.012 15.8 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM17660.1 - 0.017 14.8 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 GAM17660.1 - 0.021 14.3 0.1 0.074 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_ATPase PF09818.4 GAM17660.1 - 0.022 13.3 0.1 0.11 11.0 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 GAM17660.1 - 0.03 13.5 0.0 0.03 13.5 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAM17660.1 - 0.034 13.5 0.1 8.7 5.6 0.1 3.3 2 2 2 4 4 4 0 AAA-like domain IstB_IS21 PF01695.12 GAM17660.1 - 0.041 13.2 0.2 0.66 9.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein APS_kinase PF01583.15 GAM17660.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SbcCD_C PF13558.1 GAM17660.1 - 0.069 13.0 0.2 0.53 10.2 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 GAM17660.1 - 0.09 11.8 0.2 0.22 10.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_PrkA PF08298.6 GAM17660.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain YgaB PF14182.1 GAM17661.1 - 0.11 12.7 0.6 1.8 8.8 0.0 2.7 2 1 1 3 3 3 0 YgaB-like protein CLPTM1 PF05602.7 GAM17662.1 - 0.43 9.2 5.2 0.47 9.1 3.6 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Actin PF00022.14 GAM17663.1 - 7e-163 541.6 0.0 7.9e-163 541.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM17663.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TLD PF07534.11 GAM17664.1 - 4.7e-36 123.8 0.9 4.7e-36 123.8 0.6 3.6 4 0 0 4 4 4 1 TLD WD40 PF00400.27 GAM17664.1 - 5.5e-16 57.7 29.0 0.00013 21.7 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat LysM PF01476.15 GAM17664.1 - 1e-05 25.2 0.3 0.00029 20.6 0.0 3.3 3 0 0 3 3 3 1 LysM domain GRAM PF02893.15 GAM17664.1 - 5.6e-05 22.5 0.2 0.00014 21.2 0.1 1.6 1 0 0 1 1 1 1 GRAM domain Thioredoxin PF00085.15 GAM17665.1 - 2.5e-26 91.3 0.0 5.3e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin UBX PF00789.15 GAM17665.1 - 6.6e-15 54.9 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain ZZ PF00569.12 GAM17665.1 - 6.4e-13 48.0 5.8 1.1e-12 47.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.26 GAM17665.1 - 1.8e-08 33.9 0.1 3.7e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Thioredoxin_8 PF13905.1 GAM17665.1 - 9e-07 28.9 0.0 2.6e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 GAM17665.1 - 0.0006 19.7 0.2 0.0019 18.2 0.0 1.9 2 0 0 2 2 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM17665.1 - 0.0007 19.7 0.1 0.0007 19.7 0.0 2.8 2 2 0 2 2 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 GAM17665.1 - 0.0025 17.4 0.6 0.0063 16.1 0.0 2.0 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 GAM17665.1 - 0.0093 15.5 0.1 0.021 14.3 0.1 1.7 1 0 0 1 1 1 1 Redoxin Asp-B-Hydro_N PF05279.6 GAM17665.1 - 0.011 15.5 8.5 0.015 15.1 5.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region C1_3 PF07649.7 GAM17665.1 - 0.034 14.1 5.7 0.066 13.2 4.0 1.5 1 0 0 1 1 1 0 C1-like domain DUF4557 PF15101.1 GAM17665.1 - 0.42 10.4 5.3 0.62 9.8 3.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Atg14 PF10186.4 GAM17665.1 - 0.86 8.4 12.0 1.3 7.8 8.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 C1_2 PF03107.11 GAM17665.1 - 1.9 8.6 7.1 3.7 7.7 4.9 1.5 1 0 0 1 1 1 0 C1 domain ADK PF00406.17 GAM17668.1 - 5.6e-10 39.2 3.2 9.9e-09 35.2 2.2 2.7 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 GAM17668.1 - 3.5e-05 24.1 0.1 0.00014 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain LRR_4 PF12799.2 GAM17669.1 - 1.9e-07 30.5 2.5 0.017 14.7 0.3 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM17669.1 - 6e-07 29.1 1.0 1.4e-06 27.9 0.5 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.1 GAM17669.1 - 6.5e-07 29.0 0.1 1e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.28 GAM17669.1 - 0.001 18.7 0.9 3.1 8.1 0.1 3.0 2 0 0 2 2 2 2 Leucine Rich Repeat DUF3557 PF12078.3 GAM17669.1 - 0.016 14.9 0.2 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) LRR_7 PF13504.1 GAM17669.1 - 0.021 14.9 0.7 11 6.7 0.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 GAM17669.1 - 0.063 13.3 0.5 11 6.4 0.2 2.9 2 0 0 2 2 2 0 Leucine Rich repeat Menin PF05053.8 GAM17669.1 - 3.7 5.6 5.3 5.1 5.1 3.7 1.2 1 0 0 1 1 1 0 Menin FNIP PF05725.7 GAM17670.1 - 1.5e-113 370.5 22.4 3.5e-14 52.4 3.1 10.6 4 3 10 14 14 14 12 FNIP Repeat F-box PF00646.28 GAM17670.1 - 0.79 9.4 4.6 0.26 11.0 0.7 2.1 2 0 0 2 2 2 0 F-box domain Nucleoplasmin PF03066.10 GAM17670.1 - 3.2 7.2 7.3 5.6 6.4 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAD_binding_3 PF01494.14 GAM17671.1 - 5.3e-18 65.1 0.0 7.8e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM17671.1 - 1.8e-05 24.6 0.0 6.3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM17671.1 - 0.00012 21.1 0.0 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM17671.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family LGFP PF08310.6 GAM17671.1 - 0.0079 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 LGFP repeat SE PF08491.5 GAM17671.1 - 0.018 13.8 0.0 0.42 9.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 GAM17671.1 - 0.019 14.8 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM17671.1 - 0.02 13.3 0.0 0.034 12.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 GAM17671.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 GAM17671.1 - 0.12 12.1 0.2 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 GAM17671.1 - 0.13 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 GAM17671.1 - 0.14 11.2 0.0 0.61 9.0 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FNIP PF05725.7 GAM17672.1 - 1.3e-117 383.5 41.4 5.4e-15 55.0 0.1 13.3 5 4 2 13 13 13 12 FNIP Repeat DUF1769 PF08588.5 GAM17672.1 - 6.6e-05 22.7 14.9 5 7.1 0.0 9.8 8 4 4 12 12 12 1 Protein of unknown function (DUF1769) LRR_5 PF13306.1 GAM17672.1 - 0.093 12.4 3.0 4.3 7.0 0.0 3.3 3 1 0 3 3 3 0 Leucine rich repeats (6 copies) Band_7 PF01145.20 GAM17673.1 - 7.3e-27 94.4 1.1 9.5e-27 94.0 0.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family FNIP PF05725.7 GAM17674.1 - 8.4e-76 249.7 47.9 1.1e-11 44.5 0.1 11.0 8 3 5 14 14 14 12 FNIP Repeat Glyco_hydro_65C PF03633.10 GAM17674.1 - 0.065 13.3 0.2 9.9 6.3 0.0 4.5 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain MerC PF03203.9 GAM17674.1 - 0.083 13.2 0.0 13 6.2 0.0 3.2 3 0 0 3 3 3 0 MerC mercury resistance protein Rad60-SLD PF11976.3 GAM17675.1 - 2.4e-06 27.1 0.0 6.2e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM17675.1 - 0.0041 16.4 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2460 PF09343.5 GAM17675.1 - 0.029 13.7 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) Nsp1_C PF05064.8 GAM17675.1 - 0.07 12.7 0.1 0.098 12.3 0.1 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region Endotoxin_N PF03945.9 GAM17677.1 - 3.4e-14 52.7 0.4 5.8e-14 52.0 0.3 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain MbeB_N PF04837.7 GAM17677.1 - 0.00022 21.2 1.1 0.00045 20.2 0.8 1.5 1 0 0 1 1 1 1 MbeB-like, N-term conserved region E1-E2_ATPase PF00122.15 GAM17678.1 - 1.1e-46 158.6 4.5 1.3e-46 158.5 1.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAM17678.1 - 1.2e-19 71.6 0.1 1e-18 68.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM17678.1 - 9.5e-16 58.5 0.0 2.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM17678.1 - 1.6e-15 56.3 0.0 5.7e-15 54.5 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.16 GAM17678.1 - 4.1e-14 52.5 9.7 4.1e-14 52.5 6.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 GAM17678.1 - 3.3e-09 36.5 0.1 8.9e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM17678.1 - 0.0029 17.2 1.0 0.046 13.2 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PIRT PF15099.1 GAM17678.1 - 0.38 9.9 4.3 1.1 8.5 0.2 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2046 PF09755.4 GAM17679.1 - 6.9e-13 48.1 31.3 2.6e-12 46.2 16.2 2.1 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) DUF3919 PF13057.1 GAM17679.1 - 0.19 11.2 9.0 0.21 10.9 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3919) GAS PF13851.1 GAM17679.1 - 0.19 10.8 31.8 0.042 13.0 16.6 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1788 PF08747.6 GAM17679.1 - 0.29 10.9 7.3 0.17 11.7 3.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) AAA_27 PF13514.1 GAM17679.1 - 0.48 8.0 17.3 0.62 7.6 12.0 1.0 1 0 0 1 1 1 0 AAA domain DUF3828 PF12883.2 GAM17679.1 - 0.89 9.4 5.8 9.2 6.2 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3828) DUF3573 PF12097.3 GAM17679.1 - 1.8 7.1 8.9 4.7 5.7 6.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) TPR_MLP1_2 PF07926.7 GAM17679.1 - 2.2 8.0 29.0 0.13 11.9 15.3 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 GAM17679.1 - 2.3 7.0 25.0 0.28 10.1 9.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 GAM17679.1 - 4.4 7.1 35.1 2.9 7.7 12.0 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cas_Cas6 PF01881.11 GAM17679.1 - 5.1 7.2 10.6 3.1 8.0 5.6 1.8 1 1 1 2 2 2 0 CRISPR associated protein Cas6 Phage_GPO PF05929.6 GAM17679.1 - 7.5 5.7 8.9 9.6 5.3 6.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Vps52 PF04129.7 GAM17680.1 - 1.3e-52 178.9 24.9 3e-52 177.8 17.3 1.6 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 GAM17680.1 - 2.6e-09 35.8 27.9 5.1e-07 28.2 4.0 3.5 2 1 1 3 3 3 3 Exocyst complex component Sec3 Nitr_red_bet_C PF14711.1 GAM17680.1 - 0.045 13.2 0.5 0.17 11.3 0.1 2.1 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal Alpha_kinase PF02816.13 GAM17681.1 - 1.9e-60 203.8 0.0 1.9e-60 203.8 0.0 2.1 3 0 0 3 3 3 1 Alpha-kinase family WD40 PF00400.27 GAM17681.1 - 2.4e-45 150.8 18.5 3.1e-09 36.3 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 GAM17681.1 - 0.011 15.9 0.0 12 6.3 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain CENP-Q PF13094.1 GAM17681.1 - 0.012 15.6 6.1 0.012 15.6 4.2 4.8 1 1 3 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit Ank_2 PF12796.2 GAM17682.1 - 4.4e-60 200.0 15.6 5.9e-21 74.6 0.6 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM17682.1 - 3.1e-33 111.9 7.4 9.5e-09 34.6 0.2 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM17682.1 - 2.1e-28 98.1 8.1 5e-11 42.7 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17682.1 - 2.2e-27 94.4 5.6 6.8e-11 42.0 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17682.1 - 8.1e-24 81.3 5.4 1.5e-05 24.7 0.2 4.9 5 0 0 5 5 5 4 Ankyrin repeat Methyltransf_2 PF00891.13 GAM17683.1 - 1.6e-48 165.0 0.0 2e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM17683.1 - 0.00017 21.3 0.0 0.00041 20.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM17683.1 - 0.073 13.6 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Endotoxin_N PF03945.9 GAM17684.1 - 6.4e-14 51.8 0.2 1.1e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain MbeB_N PF04837.7 GAM17684.1 - 0.00031 20.7 0.9 0.00069 19.6 0.6 1.5 1 0 0 1 1 1 1 MbeB-like, N-term conserved region Pkinase PF00069.20 GAM17685.1 - 1.5e-35 122.6 0.8 5.1e-35 120.8 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17685.1 - 1.2e-14 54.0 0.0 4.3e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase zf-RING_2 PF13639.1 GAM17685.1 - 1.3e-06 28.1 6.1 2.7e-06 27.0 4.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM17685.1 - 1.1e-05 24.9 7.1 3.3e-05 23.4 5.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.1 GAM17685.1 - 9.6e-05 21.4 0.0 0.00022 20.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like zf-RING_5 PF14634.1 GAM17685.1 - 0.0017 17.9 7.7 0.0052 16.4 5.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM17685.1 - 0.0018 18.2 5.8 0.011 15.7 4.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM17685.1 - 0.0039 16.8 6.1 0.0098 15.5 4.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Tropomyosin_1 PF12718.2 GAM17685.1 - 0.08 12.7 54.9 0.038 13.8 5.0 3.6 1 1 3 4 4 4 0 Tropomyosin like Myosin_tail_1 PF01576.14 GAM17685.1 - 0.095 10.4 55.6 0.13 9.9 10.0 2.6 1 1 1 2 2 2 0 Myosin tail FANCL_C PF11793.3 GAM17685.1 - 0.32 10.9 3.3 0.72 9.8 2.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 GAM17685.1 - 0.39 10.6 6.8 0.15 11.9 1.9 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 GAM17685.1 - 0.39 10.8 4.0 0.59 10.2 1.6 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger GBP_C PF02841.9 GAM17685.1 - 1.5 7.9 46.0 0.14 11.3 8.9 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain zf-RING_4 PF14570.1 GAM17685.1 - 1.7 8.2 8.9 0.076 12.6 1.3 2.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain ERM PF00769.14 GAM17685.1 - 1.9 7.9 59.1 1.5 8.2 17.0 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CAF1A PF12253.3 GAM17686.1 - 2.6e-19 69.1 13.5 2.6e-19 69.1 9.3 5.6 2 2 1 3 3 3 1 Chromatin assembly factor 1 subunit A MIP-T3 PF10243.4 GAM17686.1 - 0.00021 19.9 78.9 0.00021 19.9 54.7 3.2 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 GAM17686.1 - 0.001 18.4 120.7 0.001 18.4 83.7 4.6 3 2 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mic1 PF07035.7 GAM17687.1 - 2.1e-37 128.0 5.9 6.6e-37 126.4 4.1 1.8 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like SAC3_GANP PF03399.11 GAM17688.1 - 3.2e-47 160.7 1.0 1e-46 159.1 0.7 1.9 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family RRM_1 PF00076.17 GAM17688.1 - 0.0023 17.5 0.0 0.0064 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17688.1 - 0.039 13.8 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AlaDh_PNT_N PF05222.10 GAM17688.1 - 0.075 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain RRM_6 PF14259.1 GAM17688.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Syja_N PF02383.13 GAM17690.1 - 0.011 14.5 0.1 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain TPR_12 PF13424.1 GAM17691.1 - 9.4e-09 35.0 1.1 7.7e-06 25.7 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF2075 PF09848.4 GAM17691.1 - 0.019 13.9 0.1 3.6 6.4 0.0 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_11 PF13414.1 GAM17691.1 - 0.22 11.1 3.1 0.97 9.1 0.3 2.2 1 1 1 2 2 2 0 TPR repeat TPR_1 PF00515.23 GAM17691.1 - 2.3 7.9 6.8 3.6 7.3 0.4 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Spt5-NGN PF03439.8 GAM17692.1 - 2.6e-21 75.1 0.0 6e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 GAM17692.1 - 4.1e-14 51.6 29.6 7.3e-06 25.4 0.0 7.9 8 0 0 8 8 8 5 KOW motif zf-RING_2 PF13639.1 GAM17693.1 - 3.1e-08 33.3 5.0 1.4e-07 31.1 1.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 GAM17693.1 - 0.00017 21.6 5.5 0.00017 21.6 3.8 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAM17693.1 - 0.00064 19.3 2.7 0.0034 17.0 1.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM17693.1 - 0.0047 16.6 1.6 0.0047 16.6 1.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM17693.1 - 0.012 15.2 4.3 0.031 13.9 1.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM17693.1 - 0.038 14.0 4.2 0.038 14.0 2.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM17693.1 - 0.1 12.4 2.4 0.25 11.1 0.9 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 GAM17693.1 - 1.1 9.2 5.9 0.48 10.3 1.6 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Sec62 PF03839.11 GAM17693.1 - 1.9 7.8 5.7 0.74 9.1 0.2 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Med3 PF11593.3 GAM17693.1 - 3.8 6.6 12.2 5.5 6.1 8.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_23 PF13489.1 GAM17694.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM17694.1 - 1.4e-09 38.2 0.0 3.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM17694.1 - 4.1e-09 36.2 0.0 1.9e-07 30.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM17694.1 - 2.2e-07 31.2 0.1 5.3e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM17694.1 - 0.0044 17.3 0.0 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM17694.1 - 0.097 13.2 0.0 0.36 11.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF3530 PF12048.3 GAM17694.1 - 0.098 11.6 1.2 0.19 10.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DNA_methylase PF00145.12 GAM17695.1 - 2.8e-39 135.1 0.2 1e-28 100.4 0.4 2.0 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.5 GAM17695.1 - 0.043 13.3 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase COG7 PF10191.4 GAM17697.1 - 2.5e-100 336.5 18.3 1.5e-76 257.9 9.3 2.1 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Spo0A_C PF08769.6 GAM17697.1 - 0.014 15.2 0.3 0.57 10.0 0.0 3.1 3 0 0 3 3 3 0 Sporulation initiation factor Spo0A C terminal Astro_capsid PF03115.9 GAM17697.1 - 1.8 6.7 6.8 2.8 6.0 4.7 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor E1_DerP2_DerF2 PF02221.10 GAM17699.1 - 1.3e-20 74.0 0.1 1.5e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 ML domain Peptidase_M28 PF04389.12 GAM17700.1 - 2.1e-17 63.4 0.1 3.7e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAM17700.1 - 2.5e-08 33.6 0.1 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 GAM17700.1 - 0.0049 15.6 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Ank_2 PF12796.2 GAM17701.1 - 2e-24 85.7 0.0 2e-07 31.2 0.0 4.3 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17701.1 - 9.3e-14 50.1 5.3 0.91 9.9 0.1 8.6 8 1 1 9 9 9 3 Ankyrin repeat Ank PF00023.25 GAM17701.1 - 3.1e-13 48.7 2.2 1.1 9.2 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 GAM17701.1 - 8.5e-12 45.2 6.0 0.016 15.7 0.0 7.4 5 3 3 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17701.1 - 2.4e-11 43.4 3.2 1.4 9.2 0.0 7.6 6 2 2 8 8 8 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 GAM17701.1 - 0.024 14.6 0.3 8 6.5 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) CompInhib_SCIN PF11546.3 GAM17702.1 - 0.017 14.9 0.6 0.062 13.1 0.4 2.0 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN tRNA-synt_1 PF00133.17 GAM17703.1 - 4.2e-220 731.8 0.4 5.4e-220 731.4 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM17703.1 - 4.6e-23 81.6 0.1 9.6e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM17703.1 - 1e-19 70.4 3.2 1.3e-05 24.0 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAM17703.1 - 0.00059 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 GAM17703.1 - 0.031 13.5 0.2 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Spt20 PF12090.3 GAM17704.1 - 1.3e-35 122.4 14.4 1.3e-35 122.4 9.9 4.6 2 2 1 3 3 3 1 Spt20 family Med15 PF09606.5 GAM17705.1 - 1.8 6.6 94.4 1.9 6.5 65.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 GAM17705.1 - 4.8 6.7 25.4 5.7 6.5 17.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 GAM17705.1 - 7.7 4.6 79.4 8.4 4.4 55.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPR_2 PF13041.1 GAM17706.1 - 1.5e-16 60.0 2.2 0.0024 17.8 0.0 5.0 3 1 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 GAM17706.1 - 6.8e-12 44.6 0.2 0.13 12.5 0.0 7.0 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 GAM17706.1 - 3.3e-10 39.2 0.2 0.26 11.3 0.0 5.9 5 0 0 5 5 5 3 PPR repeat TPR_19 PF14559.1 GAM17706.1 - 0.00056 20.1 0.0 6.5 7.1 0.0 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 GAM17706.1 - 0.0088 15.5 0.3 0.4 10.2 0.0 3.2 3 1 1 4 4 4 1 PPR repeat Clathrin PF00637.15 GAM17706.1 - 0.032 13.8 0.0 5.1 6.7 0.0 3.1 1 1 1 2 2 2 0 Region in Clathrin and VPS TcdA_TcdB PF12919.2 GAM17706.1 - 0.034 12.6 0.9 0.051 12.0 0.6 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Aldo_ket_red PF00248.16 GAM17707.1 - 1.6e-79 266.7 0.0 1.8e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_8 PF05148.10 GAM17707.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase N-glycanase_N PF09112.5 GAM17709.1 - 0.042 13.2 0.1 0.42 9.9 0.0 2.0 2 0 0 2 2 2 0 Peptide-N-glycosidase F, N terminal PDR_CDR PF06422.7 GAM17710.1 - 0.25 11.0 3.3 1.8 8.2 0.1 3.1 3 0 0 3 3 3 0 CDR ABC transporter HlyIII PF03006.15 GAM17711.1 - 5.4e-58 196.0 25.2 6.6e-58 195.7 17.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4611 PF15387.1 GAM17711.1 - 1.4 9.1 8.7 0.13 12.4 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Per1 PF04080.8 GAM17711.1 - 2.9 7.2 19.9 8.5 5.7 12.3 2.4 1 1 1 2 2 2 0 Per1-like BUD22 PF09073.5 GAM17711.1 - 6.7 5.6 11.7 8.9 5.2 8.1 1.0 1 0 0 1 1 1 0 BUD22 WD40 PF00400.27 GAM17712.1 - 6.5e-55 181.1 20.4 1.1e-08 34.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 GAM17712.1 - 4.2e-13 48.7 2.2 8.5e-13 47.8 1.5 1.6 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.1 GAM17712.1 - 4.4e-09 36.0 0.1 0.65 9.8 0.0 4.6 2 2 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region F-box PF00646.28 GAM17712.1 - 1.2e-07 31.2 3.4 2.6e-07 30.1 2.4 1.6 1 0 0 1 1 1 1 F-box domain DUF221 PF02714.10 GAM17713.1 - 9.1e-84 281.0 29.2 9.1e-84 281.0 20.2 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM17713.1 - 1e-38 132.3 3.2 1e-38 132.3 2.2 3.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF1836 PF08876.6 GAM17713.1 - 0.042 13.6 0.9 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) LRR19-TM PF15176.1 GAM17713.1 - 0.18 11.5 0.5 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain DUF1180 PF06679.7 GAM17713.1 - 0.57 10.0 1.3 1.4e+02 2.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) tRNA_U5-meth_tr PF05958.6 GAM17714.1 - 2.6e-18 65.8 0.0 4.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 GAM17714.1 - 2.9e-13 49.6 0.1 8.7e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM17714.1 - 7.9e-07 29.1 0.0 3.8e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM17714.1 - 2.1e-06 27.2 0.2 4.1e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM17714.1 - 1.3e-05 25.4 0.1 3.5e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM17714.1 - 5.5e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM17714.1 - 7.8e-05 23.0 0.4 0.25 11.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 GAM17714.1 - 7.9e-05 21.8 0.1 0.00016 20.9 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 GAM17714.1 - 0.00028 20.4 0.3 0.00084 18.9 0.1 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 GAM17714.1 - 0.0007 20.0 0.1 0.0019 18.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM17714.1 - 0.00072 18.9 0.0 0.0043 16.4 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PrmA PF06325.8 GAM17714.1 - 0.00081 18.5 0.4 0.0016 17.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 GAM17714.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.13 GAM17714.1 - 0.007 15.8 0.1 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 DNA methylase Met_10 PF02475.11 GAM17714.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 GAM17714.1 - 0.016 14.7 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 GAM17714.1 - 0.031 13.9 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 GAM17714.1 - 0.037 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.6 GAM17714.1 - 0.079 12.3 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SET PF00856.23 GAM17715.1 - 1.2e-11 45.1 0.0 2e-10 41.2 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 GAM17715.1 - 2.6e-10 39.7 5.5 2.5e-05 23.8 0.5 3.1 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAM17715.1 - 0.00023 20.8 3.7 0.0045 16.7 0.6 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM17715.1 - 0.0012 18.3 1.4 0.023 14.3 1.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM17715.1 - 0.0027 17.6 0.3 0.0098 15.8 0.2 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17715.1 - 0.0058 16.9 0.0 0.024 14.9 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM17715.1 - 0.019 14.7 2.9 0.024 14.4 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SEN1_N PF12726.2 GAM17715.1 - 0.02 12.9 0.3 0.14 10.2 0.0 2.2 2 1 1 3 3 3 0 SEN1 N terminal TPR_16 PF13432.1 GAM17715.1 - 0.023 15.3 0.1 0.15 12.7 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM17715.1 - 0.029 14.4 1.1 0.13 12.4 0.8 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 GAM17715.1 - 0.047 13.5 0.7 0.95 9.3 0.2 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SAF PF08666.7 GAM17715.1 - 0.16 12.3 0.0 28 5.1 0.0 2.5 2 0 0 2 2 2 0 SAF domain UCR_14kD PF02271.11 GAM17716.1 - 1.8e-14 53.3 0.2 2.1e-14 53.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Adenylsucc_synt PF00709.16 GAM17717.1 - 3.2e-168 559.7 0.0 3.7e-168 559.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase NIF3 PF01784.13 GAM17717.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) HAD_2 PF13419.1 GAM17718.1 - 2.4e-22 80.0 0.0 2.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM17718.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM17718.1 - 0.0042 17.5 0.3 0.064 13.6 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 GAM17718.1 - 0.022 14.3 0.0 7.9 6.0 0.0 2.3 2 1 0 2 2 2 0 Acid Phosphatase Pox_VLTF3 PF04947.9 GAM17718.1 - 0.04 13.4 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like UCR_14kD PF02271.11 GAM17718.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF3552 PF12072.3 GAM17719.1 - 0.0015 17.7 41.4 0.054 12.7 9.1 3.0 1 1 0 2 2 2 1 Domain of unknown function (DUF3552) Tropomyosin PF00261.15 GAM17719.1 - 0.036 13.1 29.0 0.043 12.8 20.1 1.1 1 0 0 1 1 1 0 Tropomyosin ESAG1 PF03238.8 GAM17719.1 - 0.049 12.9 0.1 0.072 12.3 0.1 1.3 1 0 0 1 1 1 0 ESAG protein DUF390 PF04094.9 GAM17719.1 - 0.051 11.6 11.5 0.062 11.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4175 PF13779.1 GAM17719.1 - 0.2 9.3 40.2 0.22 9.1 27.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GAGA_bind PF06217.7 GAM17719.1 - 0.72 9.7 21.6 1.7 8.5 14.9 1.6 1 1 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 GAM17719.1 - 3 5.3 23.0 3.9 5.0 15.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3584 PF12128.3 GAM17719.1 - 6.4 3.9 37.3 8.7 3.5 25.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 GAM17719.1 - 9.1 4.8 33.6 42 2.6 23.3 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3611 PF12263.3 GAM17720.1 - 0.092 12.1 6.8 0.5 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Oxidored_q3 PF00499.15 GAM17720.1 - 0.45 10.2 10.3 32 4.2 7.1 2.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Ank_2 PF12796.2 GAM17721.1 - 7.5e-39 131.9 35.5 5.8e-08 32.9 0.1 7.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM17721.1 - 1.2e-29 101.6 19.7 0.016 15.4 0.2 14.4 4 2 10 15 15 15 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM17721.1 - 1.8e-29 101.5 6.9 0.00076 19.9 0.0 10.7 4 3 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17721.1 - 1.6e-23 80.4 13.3 0.35 11.2 0.0 14.7 9 3 7 16 16 16 5 Ankyrin repeat Ank PF00023.25 GAM17721.1 - 1.2e-19 69.0 15.7 2.7 7.9 0.0 15.3 16 1 1 17 17 17 6 Ankyrin repeat Rbsn PF11464.3 GAM17721.1 - 0.00043 19.7 0.0 21 4.7 0.0 6.6 9 0 0 9 9 9 0 Rabenosyn Rab binding domain DUF3463 PF11946.3 GAM17721.1 - 0.022 14.3 0.2 24 4.5 0.0 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3463) zf-4CXXC_R1 PF10497.4 GAM17721.1 - 0.024 14.7 0.4 29 4.8 0.0 4.5 3 2 2 5 5 5 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Viral_Hsp90 PF03225.9 GAM17721.1 - 0.098 10.9 0.5 5.6 5.1 0.0 3.6 4 1 1 5 5 5 0 Viral heat shock protein Hsp90 homologue DUF411 PF04214.8 GAM17721.1 - 0.1 12.1 1.6 1.1 8.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF Vps53_N PF04100.7 GAM17722.1 - 1.2e-111 373.2 11.8 2.1e-111 372.4 8.2 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 GAM17722.1 - 1.2e-15 57.2 5.5 1.2e-15 57.2 3.8 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG7 PF10191.4 GAM17722.1 - 1.1e-05 23.6 8.1 0.0016 16.4 0.0 2.9 4 0 0 4 4 4 2 Golgi complex component 7 (COG7) COG5 PF10392.4 GAM17722.1 - 1.4e-05 25.0 5.3 1.6e-05 24.8 1.9 2.5 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.6 GAM17722.1 - 0.00052 19.8 5.3 0.011 15.5 3.3 3.0 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2884 PF11101.3 GAM17722.1 - 0.00096 18.5 4.8 0.0024 17.3 1.8 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) Baculo_PEP_C PF04513.7 GAM17722.1 - 0.038 13.8 3.9 0.39 10.5 0.5 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Striatin PF08232.7 GAM17722.1 - 0.91 9.8 15.0 0.13 12.6 1.6 3.0 2 1 0 2 2 2 0 Striatin family Cupin_8 PF13621.1 GAM17723.1 - 6.1e-22 78.3 0.1 7.7e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAM17723.1 - 1.5e-09 38.1 0.0 2.5e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 GAM17723.1 - 9.9e-05 21.8 0.2 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 GAM17723.1 - 0.0034 16.8 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.7 GAM17723.1 - 0.0069 15.6 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein GPI PF06560.6 GAM17723.1 - 0.0092 15.0 0.6 0.091 11.7 0.0 2.1 1 1 1 2 2 2 1 Glucose-6-phosphate isomerase (GPI) TFIIIC_delta PF12657.2 GAM17723.1 - 0.025 14.2 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Methyltransf_PK PF05891.7 GAM17724.1 - 6e-75 251.2 0.0 7.5e-75 250.9 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 GAM17724.1 - 1.6e-06 28.6 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM17724.1 - 5.1e-06 26.8 0.0 9.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM17724.1 - 2.2e-05 24.8 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM17724.1 - 0.00016 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM17724.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAM17724.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase WD40 PF00400.27 GAM17725.1 - 6.2e-72 235.1 33.1 3.5e-12 45.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAM17725.1 - 2.2e-05 23.8 0.5 7.8 6.0 0.0 5.4 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 GAM17725.1 - 2.7e-05 23.9 1.1 0.0049 16.5 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 GAM17725.1 - 0.00055 17.8 6.8 0.005 14.7 1.0 2.6 1 1 1 2 2 2 2 IKI3 family Nucleoporin_N PF08801.6 GAM17725.1 - 0.08 11.6 5.2 5.4 5.6 0.5 4.0 1 1 1 3 3 3 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 GAM17725.1 - 0.16 10.7 0.1 0.83 8.3 0.0 2.0 1 1 0 1 1 1 0 Coatomer WD associated region Prenyltrans PF00432.16 GAM17726.1 - 4.2e-26 90.1 10.0 1.2e-07 31.2 0.0 6.1 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM17726.1 - 2.3e-16 60.2 0.2 1e-06 29.0 0.1 3.7 2 1 2 4 4 4 3 Prenyltransferase-like Kua-UEV1_localn PF10520.4 GAM17727.1 - 1.8e-70 236.2 2.0 1.8e-70 236.2 1.4 1.8 1 1 1 2 2 2 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain FA_desaturase PF00487.19 GAM17727.1 - 0.0012 18.3 6.3 0.018 14.5 0.3 2.3 2 0 0 2 2 2 2 Fatty acid desaturase Asp_protease_2 PF13650.1 GAM17729.1 - 1.5e-07 31.8 0.0 2.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 GAM17729.1 - 7.7e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 GAM17729.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 GAM17729.1 - 0.00035 20.1 0.0 0.00072 19.1 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease A2M_N PF01835.14 GAM17730.1 - 0.00032 20.8 0.0 0.0022 18.2 0.0 2.5 2 0 0 2 2 2 1 MG2 domain Big_5 PF13205.1 GAM17730.1 - 0.0015 19.0 0.1 0.53 10.9 0.0 3.6 4 0 0 4 4 4 1 Bacterial Ig-like domain Adaptin_N PF01602.15 GAM17731.1 - 1.1e-83 281.4 11.1 2.1e-83 280.4 7.7 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 GAM17731.1 - 2.5e-57 192.1 0.7 9e-57 190.3 0.1 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 GAM17731.1 - 7.1e-51 171.5 0.1 1.7e-50 170.3 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 GAM17731.1 - 9.8e-07 28.9 0.0 0.0072 16.5 0.0 4.1 1 1 3 4 4 4 2 HEAT repeats HEAT PF02985.17 GAM17731.1 - 0.016 15.2 0.1 17 5.7 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Glyco_hydro_77 PF02446.12 GAM17731.1 - 0.024 13.2 0.1 0.04 12.5 0.1 1.3 1 0 0 1 1 1 0 4-alpha-glucanotransferase RhoGEF PF00621.15 GAM17732.1 - 2.3e-47 161.2 4.8 2.9e-41 141.3 1.0 2.4 2 0 0 2 2 2 2 RhoGEF domain Ima1_N PF09779.4 GAM17732.1 - 0.045 14.2 1.2 0.26 11.7 0.0 2.7 2 1 0 2 2 2 0 Ima1 N-terminal domain TIG PF01833.19 GAM17733.1 - 1.5e-63 210.7 146.3 2.3e-08 33.8 0.2 17.3 13 3 3 17 17 17 15 IPT/TIG domain EGF_2 PF07974.8 GAM17733.1 - 0.012 15.7 14.9 0.029 14.5 10.3 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM17733.1 - 0.017 15.0 10.0 0.059 13.3 6.9 2.0 1 0 0 1 1 1 0 EGF-like domain Aminotran_3 PF00202.16 GAM17733.1 - 0.031 13.1 0.0 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-III hEGF PF12661.2 GAM17733.1 - 4.1 7.6 7.5 0.29 11.3 1.1 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF HMG-CoA_red PF00368.13 GAM17734.1 - 5.5e-163 541.9 1.9 6.9e-163 541.6 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase IFP_35_N PF07334.8 GAM17734.1 - 0.23 11.4 2.5 1.2 9.2 0.0 2.3 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATG13 PF10033.4 GAM17735.1 - 0.008 15.6 0.0 0.64 9.4 0.0 3.0 2 1 1 3 3 3 1 Autophagy-related protein 13 RAP1 PF07218.6 GAM17735.1 - 0.038 12.0 3.6 0.044 11.8 2.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4210 PF13915.1 GAM17736.1 - 9.5e-19 67.4 0.0 3.6e-18 65.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) TFIIA PF03153.8 GAM17736.1 - 0.37 10.6 13.0 0.53 10.1 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.8 GAM17736.1 - 4.1 7.8 9.5 13 6.2 6.5 1.9 1 1 0 1 1 1 0 Senescence regulator FAD_binding_2 PF00890.19 GAM17737.1 - 6.6e-126 420.5 3.1 8.3e-126 420.1 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 GAM17737.1 - 7.2e-47 158.4 2.0 1.1e-46 157.8 1.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 GAM17737.1 - 3.7e-06 26.2 0.4 0.0084 15.2 0.1 3.1 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 GAM17737.1 - 4.5e-06 26.6 0.0 0.0011 18.9 0.5 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM17737.1 - 7.2e-05 21.8 2.3 0.042 12.6 1.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 GAM17737.1 - 7.9e-05 21.7 1.0 0.0011 17.9 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM17737.1 - 0.0042 16.1 0.3 0.0066 15.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM17737.1 - 0.052 12.0 0.6 0.11 10.8 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Trp_oprn_chp PF09534.5 GAM17740.1 - 0.063 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SUR7 PF06687.7 GAM17740.1 - 0.58 9.6 17.5 0.33 10.4 5.7 2.2 1 1 1 2 2 2 0 SUR7/PalI family DUF2839 PF10999.3 GAM17740.1 - 2.7 8.0 4.9 5.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) MARVEL PF01284.18 GAM17740.1 - 3 7.6 11.0 9.2 6.0 7.6 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF3816 PF12822.2 GAM17740.1 - 6.1 6.7 20.5 0.92 9.3 7.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3816) SAP PF02037.22 GAM17742.1 - 9.3e-06 25.0 0.1 0.087 12.3 0.0 3.2 3 0 0 3 3 3 2 SAP domain Rho_N PF07498.7 GAM17742.1 - 0.00065 19.4 0.1 0.7 9.7 0.0 2.9 2 0 0 2 2 2 2 Rho termination factor, N-terminal domain PPR PF01535.15 GAM17742.1 - 0.13 12.3 0.0 13 5.9 0.0 4.2 4 0 0 4 4 4 0 PPR repeat DUF3915 PF13054.1 GAM17742.1 - 0.45 10.4 4.8 0.27 11.1 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Nop14 PF04147.7 GAM17743.1 - 0.00034 18.7 48.0 0.00044 18.3 33.3 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.8 GAM17743.1 - 0.0015 18.1 30.5 0.0015 18.1 21.2 2.1 1 1 1 2 2 2 1 YL1 nuclear protein PsaN PF05479.6 GAM17743.1 - 0.12 12.3 5.1 0.2 11.6 3.5 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) BBS2_Mid PF14783.1 GAM17744.1 - 0.00062 19.5 0.2 0.65 9.7 0.0 3.7 2 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 GAM17744.1 - 0.0051 16.2 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain MMS1_N PF10433.4 GAM17744.1 - 0.048 11.8 0.0 0.048 11.8 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term GNAT_acetyltr_2 PF13718.1 GAM17746.1 - 3.9e-79 264.5 0.0 6.3e-79 263.8 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 GAM17746.1 - 2.8e-63 212.7 0.0 1.1e-62 210.8 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 GAM17746.1 - 4.2e-37 125.7 0.1 1.1e-36 124.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 GAM17746.1 - 8.7e-10 38.6 6.7 1.5e-05 25.0 0.5 2.8 1 1 1 2 2 2 2 Possible tRNA binding domain Acetyltransf_7 PF13508.1 GAM17746.1 - 0.00034 20.7 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM17746.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_30 PF13604.1 GAM17746.1 - 0.12 11.8 1.6 12 5.4 0.0 3.6 5 0 0 5 5 5 0 AAA domain His_Phos_1 PF00300.17 GAM17747.1 - 6e-43 146.6 0.0 7.6e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PPR PF01535.15 GAM17748.1 - 2.2e-05 24.0 1.9 22 5.2 0.0 5.9 5 0 0 5 5 5 2 PPR repeat PPR_2 PF13041.1 GAM17748.1 - 0.00075 19.4 6.3 0.066 13.1 0.0 5.8 6 1 1 7 7 7 1 PPR repeat family TPR_15 PF13429.1 GAM17748.1 - 0.0069 15.4 1.3 0.022 13.8 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.1 GAM17748.1 - 0.036 14.3 3.7 48 4.6 0.0 5.6 5 0 0 5 5 5 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 GAM17748.1 - 0.1 13.3 0.2 1.2e+02 3.7 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 GAM17749.1 - 1.6e-11 43.6 8.0 2.6e-11 42.9 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM17749.1 - 6.4e-11 42.1 11.2 1.2e-10 41.2 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM17749.1 - 1.2e-10 41.0 8.7 2.3e-10 40.1 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM17749.1 - 2.9e-09 36.4 10.3 5.1e-09 35.7 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM17749.1 - 4e-09 35.9 11.9 7.6e-09 35.0 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM17749.1 - 2.6e-06 27.2 7.6 1.1e-05 25.1 5.6 1.8 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 GAM17749.1 - 3.1e-05 23.9 5.4 3.1e-05 23.9 3.7 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAM17749.1 - 3.6e-05 23.3 5.6 3.8e-05 23.3 2.6 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 GAM17749.1 - 0.021 14.3 5.9 0.039 13.4 4.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 GAM17749.1 - 0.043 13.3 6.8 0.31 10.6 4.7 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 GAM17749.1 - 0.064 13.0 2.8 0.15 11.9 2.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 GAM17749.1 - 0.1 12.1 8.9 0.28 10.7 6.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 GAM17749.1 - 0.11 12.1 8.7 0.28 10.7 6.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 GAM17749.1 - 0.21 11.3 5.6 0.8 9.5 3.9 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 GAM17749.1 - 5.5 6.5 10.5 16 5.1 7.1 1.9 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger Pkinase PF00069.20 GAM17750.1 - 2.7e-45 154.5 0.2 2.6e-32 111.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17750.1 - 1.2e-28 99.8 0.0 6e-28 97.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.19 GAM17750.1 - 2.3e-05 24.3 0.0 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM17750.1 - 0.00039 20.5 0.0 0.0011 19.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Kinase-like PF14531.1 GAM17750.1 - 0.021 13.7 0.0 0.43 9.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Met_10 PF02475.11 GAM17751.1 - 2.6e-64 216.4 0.0 3.9e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 GAM17751.1 - 6.2e-07 29.4 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM17751.1 - 1.1e-06 28.1 0.0 2.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 GAM17751.1 - 4.1e-06 26.1 0.0 8.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAM17751.1 - 2.5e-05 23.9 0.1 0.0011 18.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM17751.1 - 4.8e-05 23.9 0.0 8.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 GAM17751.1 - 0.00019 20.5 0.1 0.00066 18.7 0.0 1.9 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase UPF0020 PF01170.13 GAM17751.1 - 0.015 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.5 GAM17751.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 GAM17751.1 - 0.06 13.8 0.0 0.22 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain LRR_6 PF13516.1 GAM17752.1 - 3.9e-24 81.9 67.6 0.0097 15.8 0.1 18.0 18 0 0 18 18 18 11 Leucine Rich repeat LRR_4 PF12799.2 GAM17752.1 - 1.6e-09 37.1 74.0 0.0096 15.5 1.5 11.7 6 3 5 13 13 13 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM17752.1 - 5.5e-05 22.6 42.4 23 5.5 0.0 15.5 17 1 0 17 17 17 3 Leucine Rich Repeat Pkinase PF00069.20 GAM17753.1 - 4.1e-70 235.9 0.0 7.9e-70 234.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17753.1 - 3.6e-36 124.5 0.0 6.5e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM17753.1 - 1.8e-06 27.1 0.0 6.3e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like zf-CCCH PF00642.19 GAM17754.1 - 1.2e-05 24.8 2.0 2.5e-05 23.8 1.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RanBP PF00641.13 GAM17754.1 - 0.00064 18.7 1.1 0.0025 16.8 0.7 2.1 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HGTP_anticodon PF03129.15 GAM17754.1 - 0.036 13.9 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Anticodon binding domain GCV_H PF01597.14 GAM17757.1 - 0.0035 17.0 0.0 0.034 13.8 0.0 2.0 1 1 0 1 1 1 1 Glycine cleavage H-protein Peptidase_C53 PF05550.6 GAM17757.1 - 0.047 13.1 0.1 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Pestivirus Npro endopeptidase C53 URO-D PF01208.12 GAM17758.1 - 3.6e-127 424.0 0.0 4.1e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) TPR_12 PF13424.1 GAM17759.1 - 6.2e-09 35.6 4.0 5.3e-05 23.0 1.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAM17759.1 - 0.00026 20.7 3.5 0.53 10.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM17759.1 - 0.035 13.7 6.5 0.032 13.8 1.2 2.4 1 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 GAM17759.1 - 0.15 11.7 1.4 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM17759.1 - 0.18 11.7 2.7 2.9 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.18 GAM17760.1 - 1.2e-115 386.1 3.1 1.4e-115 385.8 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM17760.1 - 5.7e-10 39.3 0.3 1.3e-09 38.2 0.2 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAM17760.1 - 6.8e-05 22.4 0.0 0.00033 20.2 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAM17760.1 - 0.0004 20.8 0.1 0.0099 16.3 0.0 2.9 2 1 1 3 3 3 1 Aspartyl protease UCH PF00443.24 GAM17761.1 - 4e-49 167.1 0.2 4.8e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM17761.1 - 1e-17 64.5 0.1 1.6e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 GAM17761.1 - 0.012 14.9 0.0 0.04 13.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family Peptidase_C98 PF15499.1 GAM17761.1 - 0.02 14.1 2.2 0.036 13.3 0.1 2.4 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Abhydrolase_2 PF02230.11 GAM17762.1 - 6.3e-56 189.2 0.1 7.5e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 GAM17762.1 - 1.9e-13 50.3 0.0 2.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM17762.1 - 3.7e-09 36.8 0.0 5.5e-07 29.7 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM17762.1 - 6.5e-05 22.2 0.4 0.45 9.7 0.0 2.9 2 1 1 3 3 3 2 Prolyl oligopeptidase family FSH1 PF03959.8 GAM17762.1 - 8.4e-05 22.1 0.1 0.0013 18.2 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 GAM17762.1 - 0.0012 18.4 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 GAM17762.1 - 0.0021 17.5 0.3 0.0046 16.4 0.2 1.6 1 1 0 1 1 1 1 Putative esterase DUF443 PF04276.7 GAM17762.1 - 0.0074 15.7 1.0 0.011 15.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF443) Abhydrolase_3 PF07859.8 GAM17762.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 GAM17762.1 - 0.027 14.2 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 GAM17762.1 - 0.029 13.7 0.1 0.16 11.2 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2974) DLH PF01738.13 GAM17762.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Nop16 PF09420.5 GAM17763.1 - 4.1e-16 59.5 10.1 4.1e-16 59.5 7.0 3.7 2 2 0 2 2 2 1 Ribosome biogenesis protein Nop16 DHHW PF14286.1 GAM17763.1 - 0.32 10.2 7.4 0.48 9.6 5.1 1.4 1 0 0 1 1 1 0 DHHW protein BSP_II PF05432.6 GAM17763.1 - 2.1 7.5 13.7 3.1 6.9 9.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ABC2_membrane_3 PF12698.2 GAM17764.1 - 9.1e-29 100.5 30.0 1.3e-28 100.0 20.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 GAM17764.1 - 2.7e-27 95.7 0.0 6.7e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM17764.1 - 6e-12 46.1 6.5 1.4e-09 38.3 0.0 3.6 4 0 0 4 4 4 2 AAA domain ABC2_membrane PF01061.19 GAM17764.1 - 2.6e-06 26.7 22.8 5.6e-06 25.6 15.8 1.5 1 0 0 1 1 1 1 ABC-2 type transporter SMC_N PF02463.14 GAM17764.1 - 2.3e-05 23.7 0.4 0.00056 19.1 0.1 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM17764.1 - 0.007 15.8 0.5 0.092 12.2 0.3 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAM17764.1 - 0.025 13.7 0.3 0.084 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM17764.1 - 0.064 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 GAM17764.1 - 0.07 13.4 0.5 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Flavi_NS4A PF01350.12 GAM17764.1 - 4 6.9 17.1 0.47 10.0 2.1 2.5 1 1 1 2 2 2 0 Flavivirus non-structural protein NS4A DUF3767 PF12597.3 GAM17766.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF1025 PF06262.6 GAM17766.1 - 0.082 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase p450 PF00067.17 GAM17767.1 - 2.4e-91 306.6 0.5 2.7e-91 306.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 GAM17768.1 - 1.6e-182 606.9 0.0 1.8e-182 606.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.17 GAM17769.1 - 3e-182 606.1 0.2 3.3e-182 605.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3940 PF13076.1 GAM17769.1 - 0.0077 15.7 0.2 0.018 14.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3940) PDZ_2 PF13180.1 GAM17769.1 - 0.038 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Ank_2 PF12796.2 GAM17771.1 - 5.5e-41 138.8 11.8 2.2e-10 40.7 0.0 5.4 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17771.1 - 2.6e-31 107.4 17.6 2.1e-05 24.8 0.0 8.1 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17771.1 - 2.5e-30 103.8 15.0 0.00062 19.9 0.1 10.8 2 2 10 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17771.1 - 5e-23 78.8 18.3 0.086 13.1 0.0 13.0 7 2 7 14 14 14 5 Ankyrin repeat Ank PF00023.25 GAM17771.1 - 3.1e-16 58.2 9.6 1.5 8.7 0.0 11.3 10 2 1 11 11 11 5 Ankyrin repeat Rbsn PF11464.3 GAM17771.1 - 0.0039 16.7 0.1 44 3.7 0.0 4.9 6 0 0 6 6 6 0 Rabenosyn Rab binding domain DUF2493 PF10686.4 GAM17771.1 - 0.0049 16.3 2.6 6 6.5 0.0 4.4 2 2 2 4 4 4 1 Protein of unknown function (DUF2493) RhoGEF PF00621.15 GAM17772.1 - 1.1e-51 175.3 3.3 3.6e-51 173.5 2.3 2.0 1 0 0 1 1 1 1 RhoGEF domain Arm PF00514.18 GAM17772.1 - 2.3e-19 68.4 10.3 0.00017 21.2 0.0 9.1 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 GAM17772.1 - 2.7e-08 33.2 22.7 0.017 14.2 0.3 5.7 4 1 1 5 5 5 4 Armadillo-like HEAT_EZ PF13513.1 GAM17772.1 - 2.6e-06 27.7 8.7 0.091 13.2 0.0 5.7 5 0 0 5 5 5 3 HEAT-like repeat MIR PF02815.14 GAM17773.1 - 1.3e-16 60.6 1.2 6.2e-12 45.4 0.1 2.9 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.6 GAM17773.1 - 6.5e-06 25.3 0.2 4.7e-05 22.5 0.0 2.0 1 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Glyco_transf_7C PF02709.9 GAM17774.1 - 0.48 9.9 15.1 25 4.4 0.0 6.6 7 0 0 7 7 7 0 N-terminal domain of galactosyltransferase ParBc_2 PF08857.6 GAM17775.1 - 8.5e-50 168.7 0.1 1.1e-49 168.4 0.1 1.1 1 0 0 1 1 1 1 Putative ParB-like nuclease CUB_2 PF02408.15 GAM17776.1 - 0.0039 16.7 0.2 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 CUB-like domain TauE PF01925.14 GAM17776.1 - 0.05 13.0 6.0 0.076 12.4 4.2 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE CelD_N PF02927.9 GAM17776.1 - 0.091 13.0 0.1 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase U-box PF04564.10 GAM17777.1 - 3.3e-14 52.6 0.1 7.7e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 U-box domain Tyr-DNA_phospho PF06087.7 GAM17778.1 - 5.3e-13 48.4 0.0 1.7e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 GAM17778.1 - 0.00095 18.9 0.0 0.0026 17.4 0.0 1.4 1 1 0 1 1 1 1 PLD-like domain RasGAP PF00616.14 GAM17779.1 - 3.1e-43 147.7 0.6 2.2e-42 144.9 0.1 3.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 GAM17779.1 - 1.6e-20 73.5 0.4 2e-19 69.9 0.3 3.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain GHL13 PF14883.1 GAM17779.1 - 0.0007 18.8 1.8 0.0035 16.5 0.1 2.6 3 0 0 3 3 3 1 Hypothetical glycosyl hydrolase family 13 ApoB100_C PF12491.3 GAM17779.1 - 0.00085 18.9 0.5 1.8 8.2 0.1 4.2 3 0 0 3 3 3 2 Apolipoprotein B100 C terminal FNIP PF05725.7 GAM17780.1 - 6.8e-80 262.8 26.7 9.7e-13 47.8 0.0 10.2 5 2 6 11 11 11 11 FNIP Repeat LRR_5 PF13306.1 GAM17780.1 - 0.015 14.9 0.5 6.6 6.4 0.0 4.4 3 2 2 5 5 5 0 Leucine rich repeats (6 copies) DUF3827 PF12877.2 GAM17781.1 - 0.0024 16.0 0.1 0.0046 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3827) DUF4448 PF14610.1 GAM17781.1 - 0.0047 16.4 0.1 0.019 14.4 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ETRAMP PF09716.5 GAM17781.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RNase_PH PF01138.16 GAM17782.1 - 6.2e-21 75.0 0.0 1.3e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAM17782.1 - 7.8e-13 48.1 0.1 1.5e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 EB PF01683.13 GAM17782.1 - 3.2 7.9 18.5 5.4 7.1 5.2 3.4 2 2 0 2 2 2 0 EB module Med31 PF05669.7 GAM17783.1 - 1.6e-37 127.3 14.1 1.6e-37 127.3 9.7 1.6 2 0 0 2 2 2 1 SOH1 Chordopox_G3 PF06129.7 GAM17783.1 - 0.038 14.1 1.3 0.038 14.1 0.9 2.3 2 1 1 3 3 3 0 Chordopoxvirus G3 protein CLN5 PF15014.1 GAM17784.1 - 1.3e-14 54.3 7.6 1.9e-14 53.7 5.3 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 M16C_assoc PF08367.6 GAM17785.1 - 2.3e-63 213.3 1.4 4.1e-63 212.5 1.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 GAM17785.1 - 2.8e-31 108.6 0.0 1.9e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM17785.1 - 7.9e-08 32.1 1.6 2.7e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Xpo1 PF08389.7 GAM17785.1 - 0.13 12.1 3.5 4.4 7.2 1.6 2.7 2 0 0 2 2 2 0 Exportin 1-like protein OEP PF02321.13 GAM17786.1 - 0.027 14.0 9.6 0.042 13.4 6.7 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein WEMBL PF05701.6 GAM17786.1 - 0.086 11.2 18.2 0.11 10.9 12.6 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light VKG_Carbox PF05090.9 GAM17787.1 - 0.00083 18.3 13.6 0.0013 17.6 9.5 1.3 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase SAP PF02037.22 GAM17788.1 - 0.031 13.7 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain Sgf11 PF08209.6 GAM17788.1 - 0.058 12.7 0.6 0.12 11.6 0.4 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf-C2H2_4 PF13894.1 GAM17788.1 - 2.6 8.5 8.9 24 5.5 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM17788.1 - 4 7.9 5.7 12 6.4 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.27 GAM17789.1 - 8.7e-23 79.3 4.2 3.5e-07 29.8 0.0 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 GAM17789.1 - 0.00012 21.6 0.0 0.00054 19.5 0.0 2.2 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PIG-P PF08510.7 GAM17789.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 PIG-P DEAD PF00270.24 GAM17790.1 - 8.8e-47 158.7 0.0 1.1e-45 155.1 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM17790.1 - 2.2e-23 81.9 0.0 5.9e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM17790.1 - 0.0076 16.0 0.1 0.039 13.7 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Herpes_UL49_1 PF03117.9 GAM17790.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 UL49 family Lipase_GDSL PF00657.17 GAM17791.1 - 1.8e-06 27.9 0.1 5.7e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.12 GAM17791.1 - 0.0052 16.7 1.7 0.0099 15.8 0.2 2.3 2 0 0 2 2 2 1 Saposin-like type B, region 2 Ank_2 PF12796.2 GAM17792.1 - 1.3e-38 131.1 10.5 5.6e-10 39.4 0.2 6.3 4 3 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM17792.1 - 6.1e-29 97.1 13.6 0.83 10.0 0.0 13.3 8 2 5 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 GAM17792.1 - 5.6e-28 96.7 9.6 0.00043 20.7 0.1 8.8 6 4 2 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.25 GAM17792.1 - 1.4e-21 75.1 13.3 3 7.8 0.0 12.9 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 GAM17792.1 - 2.9e-21 75.0 13.5 0.058 13.6 0.3 11.6 2 2 10 12 12 12 6 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM17792.1 - 0.0005 19.8 4.1 0.96 9.2 0.0 5.2 5 2 1 6 6 6 1 Domain of unknown function (DUF3447) FBD PF08387.5 GAM17792.1 - 0.19 11.1 2.8 19 4.8 0.0 4.5 5 0 0 5 5 5 0 FBD RasGEF PF00617.14 GAM17793.1 - 1.7e-59 200.6 0.2 4e-59 199.5 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RCC1 PF00415.13 GAM17793.1 - 3e-47 158.6 20.7 6.3e-13 48.7 0.0 7.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM17793.1 - 1.3e-36 123.4 19.4 4.4e-10 38.9 1.5 7.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.15 GAM17793.1 - 6.7e-20 71.7 2.0 4.9e-18 65.6 0.8 2.6 2 0 0 2 2 2 1 RhoGEF domain RasGEF_N PF00618.15 GAM17793.1 - 1e-19 70.5 0.1 4.9e-19 68.3 0.1 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif Pkinase_Tyr PF07714.12 GAM17794.1 - 6e-60 202.4 0.0 1.2e-59 201.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM17794.1 - 2e-53 181.1 0.0 7.1e-53 179.3 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 GAM17794.1 - 0.0028 16.6 0.0 0.0073 15.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like MORN PF02493.15 GAM17794.1 - 1.5 8.6 4.6 19 5.1 0.0 3.8 4 0 0 4 4 4 0 MORN repeat PAH PF02671.16 GAM17795.1 - 9.7e-50 165.9 12.4 7.8e-20 70.2 1.0 4.8 4 0 0 4 4 4 4 Paired amphipathic helix repeat Sin3_corepress PF08295.7 GAM17795.1 - 1.1e-38 131.0 0.0 6.2e-38 128.6 0.0 2.5 1 0 0 1 1 1 1 Sin3 family co-repressor ORC4_C PF14629.1 GAM17796.1 - 5.9e-16 58.4 2.6 7.7e-16 58.0 1.4 1.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 GAM17796.1 - 3.1e-09 37.0 0.1 5.1e-08 33.1 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM17796.1 - 8.7e-08 32.3 0.1 2.3e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM17796.1 - 3.3e-07 30.2 0.0 7.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 GAM17796.1 - 8.7e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAM17796.1 - 0.00011 21.8 0.2 0.0011 18.6 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 GAM17796.1 - 0.00053 19.8 0.0 0.0041 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM17796.1 - 0.0027 18.5 0.0 0.015 16.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 GAM17796.1 - 0.0038 16.1 0.0 0.01 14.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAM17796.1 - 0.0053 16.4 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 GAM17796.1 - 0.011 15.5 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 GAM17796.1 - 0.014 13.8 0.1 0.79 8.1 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein MobB PF03205.9 GAM17796.1 - 0.016 14.8 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 GAM17796.1 - 0.021 14.7 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAM17796.1 - 0.03 13.2 0.0 0.063 12.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 GAM17796.1 - 0.032 13.6 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAM17796.1 - 0.054 13.2 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 GAM17796.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 GAM17796.1 - 0.13 11.8 0.5 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ras PF00071.17 GAM17797.1 - 3.9e-42 143.3 0.1 4.6e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17797.1 - 1e-20 74.4 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17797.1 - 4.7e-18 65.0 0.0 7.1e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM17797.1 - 5.7e-07 28.9 0.0 7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM17797.1 - 5.8e-06 26.2 0.0 9.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM17797.1 - 2.9e-05 23.5 0.0 0.00026 20.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAM17797.1 - 0.0005 19.5 0.0 0.0042 16.5 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 GAM17797.1 - 0.0024 17.1 0.1 0.0043 16.3 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 GAM17797.1 - 0.012 15.1 0.1 0.089 12.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 GAM17797.1 - 0.059 13.2 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 GAM17797.1 - 0.076 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 GAM17797.1 - 0.088 12.0 0.0 0.76 9.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM17797.1 - 0.11 12.2 0.0 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Dynamin family HECT PF00632.20 GAM17800.1 - 1.2e-89 300.5 1.8 1.5e-89 300.3 0.3 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) TB2_DP1_HVA22 PF03134.14 GAM17800.1 - 0.068 12.9 0.1 10 5.9 0.0 2.6 2 0 0 2 2 2 0 TB2/DP1, HVA22 family Suf PF05843.9 GAM17801.1 - 8.9e-10 38.7 37.6 2.3e-07 30.8 0.2 5.2 2 1 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_14 PF13428.1 GAM17801.1 - 0.0036 17.8 0.0 0.49 11.1 0.0 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17801.1 - 0.013 15.8 0.0 16 5.9 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM17801.1 - 0.033 14.6 0.0 0.3 11.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Med3 PF11593.3 GAM17801.1 - 3 6.9 24.6 1.9 7.6 14.4 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal CBM49 PF09478.5 GAM17802.1 - 5.3e-17 61.6 0.0 7.4e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 NIF PF03031.13 GAM17803.1 - 8.3e-52 175.0 2.7 1.6e-51 174.1 1.9 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-Apc11 PF12861.2 GAM17805.1 - 2.3e-35 120.2 17.2 2.5e-35 120.1 11.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAM17805.1 - 2.9e-31 107.4 19.2 3.4e-31 107.1 13.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAM17805.1 - 1.9e-07 30.7 19.0 5.5e-07 29.3 13.2 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM17805.1 - 0.0044 16.6 20.1 0.0052 16.4 12.5 2.2 1 1 1 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM17805.1 - 0.0099 15.5 17.6 0.086 12.5 12.4 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 GAM17805.1 - 0.013 14.9 7.4 0.028 13.9 5.1 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 GAM17805.1 - 0.017 15.0 5.3 0.017 15.0 3.7 2.2 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 GAM17805.1 - 0.019 14.9 18.1 0.089 12.8 11.8 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2310 PF10071.4 GAM17805.1 - 0.077 11.9 0.6 0.11 11.4 0.4 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zf-RING_UBOX PF13445.1 GAM17805.1 - 0.088 12.5 6.9 0.27 10.9 4.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger GAGA PF09237.6 GAM17805.1 - 0.28 10.8 0.2 0.28 10.8 0.2 1.6 2 0 0 2 2 2 0 GAGA factor FANCL_C PF11793.3 GAM17805.1 - 1.4 8.9 16.7 7.7 6.5 11.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 GAM17805.1 - 1.7 8.6 13.4 4.9 7.2 9.3 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAM17805.1 - 2.3 8.3 15.8 28 4.9 11.0 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.2 GAM17805.1 - 5.3 7.1 17.7 0.09 12.8 5.9 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING_4 PF14570.1 GAM17805.1 - 8.7 6.0 19.1 3.8 7.1 8.3 2.5 1 1 1 2 2 1 0 RING/Ubox like zinc-binding domain Pkinase_Tyr PF07714.12 GAM17806.1 - 8.6e-37 126.5 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM17806.1 - 2e-29 102.5 0.0 3.8e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.18 GAM17806.1 - 9.8e-08 31.5 5.3 0.00028 20.5 0.1 5.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM17806.1 - 8.4e-06 25.9 0.3 0.029 14.6 0.0 4.4 2 1 3 5 5 5 1 HEAT repeats Atx10homo_assoc PF09759.4 GAM17806.1 - 0.025 14.2 8.5 0.21 11.3 0.2 4.8 4 1 2 6 6 6 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 GAM17806.1 - 0.039 14.0 0.2 2.9 8.1 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Acetyltransf_3 PF13302.1 GAM17807.1 - 2.1e-20 73.3 0.0 2.3e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM17807.1 - 3.6e-06 26.9 0.1 6.9e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM17807.1 - 0.00021 21.2 0.0 0.00031 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM17807.1 - 0.0024 17.9 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM17807.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM17807.1 - 0.049 13.7 0.1 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM17807.1 - 0.057 13.1 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Snf7 PF03357.16 GAM17808.1 - 5.3e-38 130.0 17.7 6.6e-38 129.7 12.3 1.1 1 0 0 1 1 1 1 Snf7 MCC-bdg_PDZ PF10506.4 GAM17808.1 - 0.026 14.3 3.9 0.08 12.7 2.7 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3091 PF11291.3 GAM17808.1 - 0.12 12.3 7.3 0.25 11.3 3.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) B5 PF03484.10 GAM17808.1 - 0.15 11.9 0.5 1.3 8.8 0.4 2.6 2 1 0 2 2 2 0 tRNA synthetase B5 domain TraF_2 PF13729.1 GAM17808.1 - 0.73 8.5 3.2 0.93 8.2 0.7 1.9 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DUF2443 PF10398.4 GAM17808.1 - 2.4 8.0 5.9 4.2 7.2 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2443) RWP-RK PF02042.10 GAM17810.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain HTH_8 PF02954.14 GAM17810.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family CorA PF01544.13 GAM17811.1 - 8.1e-09 34.9 6.0 8.1e-09 34.9 4.2 1.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein BAF1_ABF1 PF04684.8 GAM17811.1 - 0.041 12.7 20.9 0.063 12.1 14.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mss4 PF04421.8 GAM17811.1 - 0.096 12.5 2.2 0.16 11.7 0.3 2.3 2 0 0 2 2 2 0 Mss4 protein DUF3818 PF12825.2 GAM17812.1 - 2.4e-18 65.9 16.5 4.9e-12 45.1 0.9 3.4 2 1 1 3 3 3 2 Domain of unknown function in PX-proteins (DUF3818) DUF3439 PF11921.3 GAM17812.1 - 0.65 9.7 18.2 0.057 13.1 7.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-C3Hc3H PF13891.1 GAM17813.1 - 6.6e-08 32.5 7.0 1.2e-07 31.6 4.8 1.4 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.6 GAM17813.1 - 0.00028 20.4 0.6 0.00028 20.4 0.4 2.8 3 0 0 3 3 3 1 Primase zinc finger zf-TRM13_CCCH PF11722.3 GAM17813.1 - 0.21 11.0 11.7 0.12 11.7 2.6 2.6 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein CDC45 PF02724.9 GAM17813.1 - 6.4 4.6 41.9 0.046 11.7 6.9 2.3 2 0 0 2 2 2 0 CDC45-like protein Pro_isomerase PF00160.16 GAM17814.1 - 5.9e-47 159.7 0.1 6.7e-47 159.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M24 PF00557.19 GAM17815.1 - 6.4e-44 150.0 0.0 9e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4201 PF13870.1 GAM17816.1 - 3.2e-09 36.4 24.1 8e-07 28.6 5.5 9.3 2 1 9 11 11 9 2 Domain of unknown function (DUF4201) IncA PF04156.9 GAM17816.1 - 1.7e-07 30.9 16.0 1.7e-07 30.9 11.1 8.7 2 2 5 7 7 5 1 IncA protein Filament PF00038.16 GAM17816.1 - 4.2e-07 29.7 66.7 0.00018 21.1 2.4 7.8 2 1 5 7 7 6 4 Intermediate filament protein HOOK PF05622.7 GAM17816.1 - 1.5e-05 23.0 27.5 1.5e-05 23.0 19.1 6.3 2 1 2 4 4 3 1 HOOK protein Myosin_tail_1 PF01576.14 GAM17816.1 - 2.7e-05 22.1 66.9 2.7e-05 22.1 46.4 4.1 2 1 2 4 4 4 2 Myosin tail Reo_sigmaC PF04582.7 GAM17816.1 - 9.1e-05 21.7 12.8 9.1e-05 21.7 8.8 6.7 2 1 7 9 9 9 5 Reovirus sigma C capsid protein CCDC155 PF14662.1 GAM17816.1 - 0.00093 18.8 23.0 0.00093 18.8 16.0 6.9 2 1 2 5 5 4 2 Coiled-coil region of CCDC155 APG6 PF04111.7 GAM17816.1 - 0.0011 18.1 8.1 0.0011 18.1 5.6 8.5 2 2 7 9 9 7 5 Autophagy protein Apg6 GAS PF13851.1 GAM17816.1 - 0.0017 17.6 21.0 0.0017 17.6 14.6 7.5 2 1 4 7 7 7 2 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 GAM17816.1 - 0.0033 17.4 11.5 0.0033 17.4 8.0 7.7 1 1 4 6 6 4 1 Fez1 Phage_GP20 PF06810.6 GAM17816.1 - 0.0055 16.1 6.7 0.0055 16.1 4.6 11.0 3 1 10 13 13 11 7 Phage minor structural protein GP20 ADIP PF11559.3 GAM17816.1 - 0.011 15.5 15.4 0.011 15.5 10.7 10.6 3 1 8 12 12 9 0 Afadin- and alpha -actinin-Binding DUF465 PF04325.8 GAM17816.1 - 1.3 8.7 42.9 0.32 10.7 0.7 10.1 5 2 5 10 10 10 0 Protein of unknown function (DUF465) NRDE-2 PF08424.5 GAM17817.1 - 2.3e-68 230.4 16.1 6.5e-57 192.8 2.2 3.9 4 0 0 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 GAM17817.1 - 6.7e-09 35.5 6.3 0.13 12.9 0.1 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat HRDC PF00570.18 GAM17817.1 - 4.9e-05 22.9 0.1 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 1 HRDC domain TPR_15 PF13429.1 GAM17817.1 - 0.0045 16.0 0.0 0.0045 16.0 0.0 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM17817.1 - 0.017 15.8 4.6 7.6 7.3 0.0 4.7 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM17817.1 - 0.03 14.6 8.8 12 6.3 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat COX16 PF14138.1 GAM17818.1 - 5.1e-08 32.9 0.1 1.4e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 dCMP_cyt_deam_1 PF00383.17 GAM17819.1 - 8.6e-15 54.2 0.1 1.5e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAM17819.1 - 0.0011 18.8 1.2 0.11 12.3 0.0 2.8 2 1 1 3 3 3 2 Bd3614-like deaminase zf-RING_2 PF13639.1 GAM17819.1 - 2.5 7.9 6.0 0.8 9.5 0.5 2.6 3 0 0 3 3 3 0 Ring finger domain Gelsolin PF00626.17 GAM17820.1 - 3.6e-21 74.6 0.0 1.1e-07 31.3 0.0 10.9 11 1 0 12 12 12 5 Gelsolin repeat VHP PF02209.14 GAM17820.1 - 1.5e-12 46.9 0.2 4.3e-12 45.4 0.2 1.9 1 0 0 1 1 1 1 Villin headpiece domain DUF997 PF06196.7 GAM17821.1 - 0.031 13.7 1.4 0.056 12.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF2207 PF09972.4 GAM17821.1 - 0.3 9.6 1.9 0.33 9.5 0.6 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 GAM17821.1 - 2.4 8.2 7.9 14 5.7 4.0 2.6 2 1 1 3 3 3 0 Protein of unknown function 7TMR-DISM_7TM PF07695.6 GAM17821.1 - 4.6 6.8 14.0 0.058 13.0 3.4 2.2 3 0 0 3 3 3 0 7TM diverse intracellular signalling PI3Ka PF00613.15 GAM17822.1 - 3.5e-50 169.7 1.4 3.5e-50 169.7 1.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM17822.1 - 9e-38 130.0 0.0 2.5e-37 128.5 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM17822.1 - 3.1e-10 39.9 0.5 7.5e-10 38.7 0.3 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 FlxA PF14282.1 GAM17822.1 - 0.24 11.3 14.0 0.023 14.6 4.9 2.9 2 0 0 2 2 2 0 FlxA-like protein adh_short PF00106.20 GAM17823.1 - 5.8e-08 32.8 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM17823.1 - 7e-06 25.8 0.2 3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 KR domain Helicase_C_2 PF13307.1 GAM17823.1 - 0.033 14.1 0.0 0.089 12.7 0.0 1.6 2 0 0 2 2 2 0 Helicase C-terminal domain Eno-Rase_NADH_b PF12242.3 GAM17823.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM17823.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WD40 PF00400.27 GAM17824.1 - 1.9e-70 230.4 19.8 3.8e-13 48.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM17824.1 - 7.5e-14 51.8 0.3 1.3e-06 28.2 0.0 4.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM17824.1 - 4.6e-09 34.9 4.1 0.0097 14.0 0.1 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 GAM17824.1 - 2.2e-07 29.5 0.2 0.0084 14.4 0.0 4.0 1 1 2 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 GAM17824.1 - 2.2e-06 27.3 0.3 2.8e-05 23.7 0.0 2.3 1 1 1 3 3 3 1 PQQ-like domain DUF3312 PF11768.3 GAM17824.1 - 4.9e-06 25.0 0.1 2.8e-05 22.5 0.0 2.0 1 1 2 3 3 3 1 Protein of unknown function (DUF3312) Hira PF07569.6 GAM17824.1 - 0.0001 21.5 1.5 2.1 7.5 0.0 4.5 1 1 4 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.7 GAM17824.1 - 0.002 17.7 1.2 16 5.3 0.1 4.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 GAM17824.1 - 0.007 15.2 1.0 0.11 11.2 0.2 2.6 1 1 0 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 GAM17824.1 - 0.0098 14.6 12.5 1.9 7.1 0.4 4.5 1 1 4 5 5 5 3 Nup133 N terminal like IKI3 PF04762.7 GAM17824.1 - 0.012 13.4 0.0 0.016 13.0 0.0 1.3 1 0 0 1 1 1 0 IKI3 family DUF1513 PF07433.6 GAM17824.1 - 0.05 12.5 0.0 6.3 5.5 0.0 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1513) Vac_Fusion PF02346.11 GAM17824.1 - 0.15 11.4 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Mito_fiss_reg PF05308.6 GAM17825.1 - 0.38 10.0 13.6 0.53 9.6 9.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 GAM17825.1 - 6.2 6.0 16.9 5.1 6.2 11.2 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-4CXXC_R1 PF10497.4 GAM17826.1 - 4.6e-08 33.1 14.4 9.5e-08 32.1 10.0 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PEHE PF15275.1 GAM17826.1 - 0.0021 18.5 1.4 0.0021 18.5 1.0 2.5 3 0 0 3 3 3 1 PEHE domain DDE_1 PF03184.14 GAM17828.1 - 6e-16 58.2 0.2 7.7e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 GAM17828.1 - 0.003 17.3 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-L PF13092.1 GAM17828.1 - 0.071 12.8 0.1 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 HTH_Tnp_Tc5 PF03221.11 GAM17829.1 - 8.2e-06 25.5 0.2 2.7e-05 23.8 0.1 1.9 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Transglut_core2 PF13369.1 GAM17829.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF3647 PF12363.3 GAM17829.1 - 0.14 12.2 0.9 1.1 9.3 0.0 2.6 2 1 1 3 3 3 0 Phage protein Beta_helix PF13229.1 GAM17831.1 - 2.4e-14 53.3 37.3 4.6e-09 36.2 6.0 3.5 1 1 2 3 3 3 3 Right handed beta helix region Transferase PF02458.10 GAM17832.1 - 4.2e-24 84.7 0.0 2.7e-19 68.9 0.0 2.2 2 1 0 2 2 2 2 Transferase family UDPGP PF01704.13 GAM17833.1 - 4.6e-162 539.3 4.9 5.5e-162 539.0 3.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase BTB_2 PF02214.17 GAM17835.1 - 5.7e-17 61.7 1.3 9e-17 61.0 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain Med15 PF09606.5 GAM17835.1 - 0.00064 18.0 10.1 0.00064 18.0 7.0 2.0 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal BTB PF00651.26 GAM17835.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HpaB_N PF11794.3 GAM17835.1 - 0.52 9.6 6.6 0.1 11.9 0.9 1.9 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Myosin_head PF00063.16 GAM17836.1 - 7.8e-257 853.7 0.1 1.6e-256 852.7 0.1 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM17836.1 - 4.1e-55 186.1 3.5 7.4e-55 185.3 2.4 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 GAM17836.1 - 1.7e-19 68.9 0.8 3.6e-19 67.8 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM17836.1 - 4.5e-19 67.7 0.2 1.2e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM17836.1 - 1.9e-16 59.2 0.1 3.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 GAM17836.1 - 0.0025 17.9 0.0 0.016 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 GAM17836.1 - 0.0063 15.5 0.1 0.016 14.2 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 GAM17836.1 - 0.011 14.8 0.0 0.03 13.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 GAM17836.1 - 0.013 16.3 1.3 0.18 12.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 GAM17836.1 - 0.047 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 GAM17836.1 - 0.052 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 GAM17836.1 - 0.099 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 GAM17836.1 - 0.1 11.7 0.1 0.66 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 GAM17836.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 GAM17836.1 - 0.33 11.2 1.7 0.8 9.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter PNK3P PF08645.6 GAM17837.1 - 1.5e-49 167.4 0.0 2.4e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 GAM17837.1 - 6.4e-21 74.7 0.3 7e-20 71.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM17837.1 - 1.7e-07 30.5 0.0 0.00082 18.5 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 GAM17837.1 - 5.1e-06 25.8 1.4 0.067 12.3 0.0 2.6 3 0 0 3 3 3 2 Chromatin associated protein KTI12 BSP_II PF05432.6 GAM17837.1 - 0.0047 16.2 24.7 0.0078 15.5 17.1 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Hydrolase_like PF13242.1 GAM17837.1 - 0.0061 16.2 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like AAA_17 PF13207.1 GAM17837.1 - 0.092 13.5 0.2 4.1 8.2 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.1 GAM17837.1 - 0.14 12.3 0.9 0.47 10.5 0.0 2.4 3 1 0 3 3 3 0 AAA domain Daxx PF03344.10 GAM17837.1 - 0.35 9.3 12.8 0.46 8.9 8.9 1.1 1 0 0 1 1 1 0 Daxx Family Pox_Ag35 PF03286.9 GAM17837.1 - 0.76 9.2 17.5 1.3 8.5 12.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_S64 PF08192.6 GAM17837.1 - 1.4 7.1 7.2 2.3 6.4 5.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Nop14 PF04147.7 GAM17837.1 - 1.5 6.6 17.8 1.9 6.2 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family Mitofilin PF09731.4 GAM17837.1 - 2.6 6.5 18.0 3.4 6.1 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ycf1 PF05758.7 GAM17837.1 - 8.6 3.9 11.1 12 3.5 7.7 1.0 1 0 0 1 1 1 0 Ycf1 Cyclin_N PF00134.18 GAM17838.1 - 8e-23 80.3 6.0 1.4e-20 73.1 0.3 3.0 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM17838.1 - 0.00022 21.1 0.0 0.00022 21.1 0.0 4.1 4 1 0 5 5 5 1 Cyclin, C-terminal domain Nucleo_P87 PF07267.6 GAM17838.1 - 3.9 6.0 9.7 6.9 5.2 6.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Patatin PF01734.17 GAM17839.1 - 5.3e-14 52.6 0.9 5.7e-06 26.3 0.1 2.1 1 1 1 2 2 2 2 Patatin-like phospholipase DUF846 PF05832.7 GAM17840.1 - 3.8e-48 162.8 16.2 4.5e-48 162.5 11.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DcuC PF03606.10 GAM17840.1 - 0.001 17.4 0.6 0.0013 17.0 0.3 1.2 1 1 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DUF619 PF04768.8 GAM17840.1 - 0.018 14.4 1.8 0.03 13.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF619) Tic20 PF09685.5 GAM17840.1 - 2.8 7.9 15.0 0.29 11.1 1.6 2.2 2 0 0 2 2 2 0 Tic20-like protein MCLC PF05934.6 GAM17840.1 - 5 5.2 7.6 2.1 6.5 0.8 2.1 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) Ank_4 PF13637.1 GAM17841.1 - 0.0069 16.8 0.2 0.17 12.4 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Pectate_lyase PF03211.8 GAM17841.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase Invasin_D3 PF09134.5 GAM17841.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Invasin, domain 3 DUF3430 PF11912.3 GAM17842.1 - 1.8e-20 73.7 9.1 2.4e-20 73.2 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF2828 PF11443.3 GAM17843.1 - 9.2e-160 532.3 0.1 1.3e-130 436.1 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) DUF3124 PF11322.3 GAM17843.1 - 0.038 13.8 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) VWA_3 PF13768.1 GAM17843.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain bZIP_2 PF07716.10 GAM17843.1 - 1.5 8.7 7.1 0.31 10.9 1.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Cyclin PF08613.6 GAM17844.1 - 9.7e-29 100.7 0.2 1.2e-28 100.4 0.2 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAM17844.1 - 4.1e-11 42.5 0.0 5.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Amidohydro_1 PF01979.15 GAM17846.1 - 5.7e-24 85.3 0.2 7.4e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM17846.1 - 6.8e-19 68.9 0.0 1e-18 68.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM17846.1 - 3.8e-12 45.8 1.4 1.2e-11 44.2 0.9 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 GAM17846.1 - 1.5e-06 28.0 0.1 2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM17846.1 - 2.2e-06 27.1 0.8 0.0044 16.2 0.0 2.5 1 1 0 2 2 2 2 Amidohydrolase family D-aminoacyl_C PF07908.7 GAM17846.1 - 0.042 13.1 1.4 0.3 10.4 0.1 2.7 3 0 0 3 3 3 0 D-aminoacylase, C-terminal region Motile_Sperm PF00635.21 GAM17846.1 - 0.13 11.8 0.1 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DnaJ PF00226.26 GAM17847.1 - 2.3e-19 68.8 1.9 1.5e-18 66.2 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Acetyltransf_11 PF13720.1 GAM17847.1 - 0.059 13.5 1.7 16 5.8 0.0 3.5 2 2 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Cytochrom_B_N_2 PF13631.1 GAM17847.1 - 0.16 11.7 0.7 0.24 11.2 0.1 1.7 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF2140 PF09911.4 GAM17847.1 - 0.22 10.6 2.2 0.25 10.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) SapB_1 PF05184.10 GAM17847.1 - 5.7 6.8 5.5 4.6 7.1 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF843 PF05814.6 GAM17848.1 - 0.096 12.4 0.3 0.097 12.4 0.2 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) ODV-E18 PF10717.4 GAM17848.1 - 1.2 8.6 3.2 1.3 8.5 2.2 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Myotub-related PF06602.9 GAM17849.1 - 1.9e-123 411.7 0.1 3.4e-123 410.9 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PI3K_rbd PF00794.13 GAM17849.1 - 0.0011 18.9 1.5 0.62 10.0 0.0 3.5 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain Y_phosphatase PF00102.22 GAM17849.1 - 0.0023 17.3 0.0 0.0048 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM17849.1 - 0.0023 17.5 0.0 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain GRAM PF02893.15 GAM17849.1 - 0.0054 16.2 0.0 0.017 14.6 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 GAM17849.1 - 0.028 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family CCDC92 PF14916.1 GAM17849.1 - 0.029 13.9 0.1 0.09 12.3 0.1 1.8 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Solute_trans_a PF03619.11 GAM17850.1 - 4.2e-99 331.2 27.9 5e-99 331.0 19.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF3371 PF11851.3 GAM17851.1 - 0.022 15.4 2.7 0.022 15.4 1.9 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3371) Kinesin PF00225.18 GAM17852.1 - 7e-76 255.0 0.1 7e-76 255.0 0.0 3.0 2 1 0 2 2 2 1 Kinesin motor domain Myosin_tail_1 PF01576.14 GAM17852.1 - 0.00039 18.3 40.7 0.00067 17.5 28.2 1.3 1 0 0 1 1 1 1 Myosin tail EGF_2 PF07974.8 GAM17855.1 - 0.007 16.4 11.4 0.013 15.6 7.9 1.5 1 0 0 1 1 1 1 EGF-like domain Ribosomal_L10 PF00466.15 GAM17856.1 - 1.4e-13 50.6 0.0 2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4185 PF13810.1 GAM17856.1 - 0.031 13.1 0.0 0.061 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4185) RhoGEF PF00621.15 GAM17857.1 - 1.3e-46 158.7 0.2 1.4e-45 155.3 0.0 2.5 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM17857.1 - 1.1e-05 25.5 0.0 3.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 PH domain IQ PF00612.22 GAM17857.1 - 0.038 13.6 1.0 0.075 12.7 0.7 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glycolipid_bind PF06475.6 GAM17858.1 - 0.031 13.4 0.2 0.041 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative glycolipid-binding Neisseria_TspB PF05616.8 GAM17858.1 - 0.14 10.4 22.8 0.21 9.9 15.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cytadhesin_P30 PF07271.6 GAM17858.1 - 3.6 6.7 20.0 0.33 10.1 10.6 1.5 2 0 0 2 2 2 0 Cytadhesin P30/P32 Pox_Ag35 PF03286.9 GAM17858.1 - 3.7 7.0 12.1 1.2 8.5 6.2 1.6 1 1 0 2 2 2 0 Pox virus Ag35 surface protein YjeF_N PF03853.10 GAM17859.1 - 1e-38 132.5 0.0 1.2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Trypsin_2 PF13365.1 GAM17860.1 - 1e-25 90.0 0.0 4.9e-16 58.7 0.0 2.9 2 1 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.21 GAM17860.1 - 1.6e-10 40.9 0.1 2.8e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Trypsin Peptidase_S46 PF10459.4 GAM17860.1 - 0.0036 15.7 0.6 4.1 5.7 0.0 3.2 3 0 0 3 3 3 2 Peptidase S46 FAT PF02259.18 GAM17861.1 - 6.8e-41 140.4 0.2 2.1e-40 138.8 0.0 2.0 2 0 0 2 2 2 1 FAT domain TSA PF03249.8 GAM17862.1 - 0.016 13.8 1.9 0.031 12.8 1.3 1.4 1 0 0 1 1 1 0 Type specific antigen HD_assoc PF13286.1 GAM17862.1 - 1.3 9.3 3.8 2.6 8.3 0.3 2.9 3 0 0 3 3 3 0 Phosphohydrolase-associated domain 5_nucleotid PF05761.9 GAM17863.1 - 4.3e-172 572.6 1.7 5.2e-172 572.3 1.2 1.1 1 0 0 1 1 1 1 5' nucleotidase family Metallophos_C PF14008.1 GAM17864.1 - 6.5e-16 58.1 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAM17864.1 - 3.6e-15 55.9 0.9 5.5e-15 55.2 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 GAM17864.1 - 3.2e-07 29.3 0.2 5e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAM17864.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cna_B PF05738.8 GAM17867.1 - 3.9e-16 58.5 41.3 0.003 17.2 0.1 13.5 13 3 2 15 15 15 7 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM17867.1 - 2.6e-13 49.8 23.4 0.012 15.5 0.1 12.1 11 4 1 12 12 12 5 Carboxypeptidase regulatory-like domain DUF3244 PF11589.3 GAM17867.1 - 6e-08 32.3 0.3 3.3 7.4 0.0 7.1 8 0 0 8 8 8 3 Domain of unknown function (DUF3244) Y_Y_Y PF07495.8 GAM17867.1 - 0.00068 19.3 0.1 43 3.9 0.0 6.7 8 0 0 8 8 8 0 Y_Y_Y domain DUF2012 PF09430.5 GAM17867.1 - 0.021 14.6 0.0 0.79 9.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) VCBS PF13517.1 GAM17867.1 - 3.4 8.1 20.2 1.9 8.9 0.0 6.3 7 0 0 7 7 7 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_5 PF13202.1 GAM17868.1 - 0.5 9.7 1.1 0.94 8.9 0.7 1.4 1 0 0 1 1 1 0 EF hand DUF4211 PF13926.1 GAM17869.1 - 5.8e-34 116.7 2.0 1.2e-33 115.7 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Ank_2 PF12796.2 GAM17870.1 - 8.3e-62 205.5 6.4 7.4e-16 58.2 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM17870.1 - 2.2e-44 147.1 8.3 3.7e-06 26.4 0.0 11.8 11 1 1 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 GAM17870.1 - 2.3e-40 136.2 3.6 1.9e-07 31.4 0.0 8.6 3 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17870.1 - 2.6e-39 132.3 3.3 1.8e-10 40.6 0.0 7.8 6 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17870.1 - 1e-32 108.9 8.8 6.1e-06 25.9 0.0 12.1 12 1 0 12 12 12 8 Ankyrin repeat Plant_tran PF04827.9 GAM17870.1 - 0.022 14.1 0.0 6.3 6.1 0.0 2.6 3 0 0 3 3 3 0 Plant transposon protein SR-25 PF10500.4 GAM17870.1 - 0.063 12.7 10.0 0.11 12.0 6.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.14 GAM17871.1 - 1.1e-27 96.9 0.1 2.5e-27 95.7 0.0 1.6 2 0 0 2 2 2 1 VIT family PepSY_TM_2 PF13703.1 GAM17871.1 - 0.014 15.5 0.1 0.044 13.9 0.1 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix AIF_C PF14721.1 GAM17871.1 - 0.27 11.4 1.9 0.62 10.3 1.3 1.6 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cyt-b5 PF00173.23 GAM17872.1 - 4e-19 68.1 0.1 7.2e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.5 GAM17872.1 - 2.9e-06 26.9 1.1 6.6e-06 25.8 0.8 1.6 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Mucin PF01456.12 GAM17872.1 - 3.5 7.4 21.3 1.9 8.2 5.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Metallophos PF00149.23 GAM17873.1 - 0.0037 16.6 0.6 0.025 13.9 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_16 PF00722.16 GAM17874.1 - 1.9e-25 89.2 1.9 2.3e-25 88.9 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAM17874.1 - 1.3e-07 30.1 2.7 6.1e-06 24.6 0.6 2.4 1 1 1 3 3 3 2 Beta-glucan synthesis-associated protein (SKN1) VGCC_alpha2 PF08473.6 GAM17874.1 - 0.14 11.9 0.8 12 5.7 0.2 2.2 2 0 0 2 2 2 0 Neuronal voltage-dependent calcium channel alpha 2acd Beta-lactamase PF00144.19 GAM17877.1 - 7.9e-42 143.4 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M15 PF01427.12 GAM17877.1 - 4.1e-29 101.6 0.0 8.9e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 D-ala-D-ala dipeptidase VanY PF02557.12 GAM17877.1 - 9.1e-05 22.3 0.1 0.00017 21.4 0.1 1.5 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_S11 PF00768.15 GAM17877.1 - 0.25 10.5 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Tropomyosin_1 PF12718.2 GAM17878.1 - 1.9e-05 24.5 8.8 1.9e-05 24.5 6.1 3.0 2 1 0 2 2 2 1 Tropomyosin like Tropomyosin PF00261.15 GAM17878.1 - 0.0098 15.0 7.7 0.0098 15.0 5.3 2.7 3 0 0 3 3 3 1 Tropomyosin DUF641 PF04859.7 GAM17878.1 - 0.017 14.8 5.0 0.017 14.8 3.5 2.7 2 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Atg14 PF10186.4 GAM17878.1 - 0.028 13.3 18.5 0.051 12.5 7.5 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FerA PF08165.6 GAM17878.1 - 0.038 13.6 0.5 0.13 11.9 0.4 1.9 1 0 0 1 1 1 0 FerA (NUC095) domain Reo_sigmaC PF04582.7 GAM17878.1 - 0.046 12.9 8.5 0.028 13.5 3.4 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 GAM17878.1 - 0.062 13.1 21.9 0.064 13.0 7.2 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Med4 PF10018.4 GAM17878.1 - 0.1 11.9 14.6 0.4 10.0 1.9 2.7 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4164 PF13747.1 GAM17878.1 - 0.18 11.9 0.2 0.18 11.9 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.17 GAM17878.1 - 0.2 11.7 18.8 5.2 7.1 0.3 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.15 GAM17878.1 - 0.21 11.3 23.7 0.4 10.4 4.1 3.9 3 1 1 4 4 4 0 Prefoldin subunit Uds1 PF15456.1 GAM17878.1 - 0.25 11.3 17.2 1.2 9.1 0.5 3.4 2 2 1 3 3 3 0 Up-regulated During Septation AAA_13 PF13166.1 GAM17878.1 - 0.31 9.4 27.4 0.02 13.3 7.9 2.0 1 1 1 2 2 2 0 AAA domain APG6 PF04111.7 GAM17878.1 - 0.6 9.1 28.4 3.8 6.4 8.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 COG5 PF10392.4 GAM17878.1 - 0.65 9.9 15.8 6.4 6.7 3.5 3.5 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Tweety PF04906.8 GAM17878.1 - 0.75 8.1 7.4 0.75 8.1 0.2 2.3 2 1 1 3 3 3 0 Tweety DUF3391 PF11871.3 GAM17878.1 - 1.4 9.1 8.7 0.12 12.6 2.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) CENP-Q PF13094.1 GAM17878.1 - 1.6 8.7 17.0 0.63 10.0 4.1 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 GAM17878.1 - 2.7 7.5 28.4 13 5.3 13.1 3.0 1 1 0 2 2 2 0 IncA protein DUF948 PF06103.6 GAM17878.1 - 3.1 7.7 14.5 7.6 6.4 4.1 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 GAM17878.1 - 3.5 7.9 12.8 8.7 6.6 2.4 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 GAM17878.1 - 4.4 7.0 14.5 0.5 10.1 3.8 2.9 3 0 0 3 3 3 0 Laminin Domain II DUF4140 PF13600.1 GAM17878.1 - 4.7 7.7 9.9 0.78 10.2 1.7 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Kinesin-relat_1 PF12711.2 GAM17878.1 - 5.7 7.4 14.8 0.33 11.3 3.5 3.1 3 0 0 3 3 3 0 Kinesin motor Spc7 PF08317.6 GAM17878.1 - 6 5.4 30.4 0.88 8.1 14.7 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 GAM17878.1 - 7 6.5 24.8 1.5 8.6 7.6 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 GAM17878.1 - 7.6 6.5 12.0 1.7 8.5 4.0 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YvrJ PF12841.2 GAM17878.1 - 9.2 5.6 11.4 2 7.7 0.9 3.1 3 0 0 3 3 3 0 YvrJ protein family RhoGAP PF00620.22 GAM17879.1 - 2.3e-38 131.1 1.8 2.4e-38 131.1 0.2 1.8 2 0 0 2 2 2 1 RhoGAP domain C2 PF00168.25 GAM17879.1 - 2.9e-18 65.4 0.2 9.5e-18 63.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain PH PF00169.24 GAM17879.1 - 9.3e-13 48.2 1.9 1.8e-12 47.4 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 GAM17879.1 - 1e-08 34.9 2.9 1.2e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 GAM17879.1 - 6.4e-05 23.0 0.0 0.00041 20.5 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 GAM17879.1 - 0.0072 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain WD40 PF00400.27 GAM17880.1 - 5.7e-10 38.6 1.0 0.0015 18.3 0.2 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 GAM17880.1 - 0.002 17.0 0.6 1.9 7.1 0.0 2.9 2 1 1 3 3 3 2 Coatomer WD associated region TFIIIC_delta PF12657.2 GAM17881.1 - 3.6e-13 49.5 0.0 8.3e-09 35.3 0.0 2.5 1 1 1 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 GAM17881.1 - 0.0048 16.7 3.4 0.0097 15.7 2.4 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PIN PF01850.16 GAM17881.1 - 0.14 12.5 0.1 12 6.2 0.0 2.3 2 0 0 2 2 2 0 PIN domain RhoGEF PF00621.15 GAM17882.1 - 1.2e-43 149.0 0.6 1.2e-43 149.0 0.4 3.3 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.24 GAM17882.1 - 1.7e-06 28.1 1.7 3.7e-06 27.0 0.1 2.5 2 0 0 2 2 2 1 PH domain IQ PF00612.22 GAM17882.1 - 2.4e-06 26.6 0.2 5.4e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Beach PF02138.13 GAM17883.1 - 6.1e-109 363.6 0.6 6.1e-109 363.6 0.4 2.2 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.27 GAM17883.1 - 1.3e-15 56.5 17.1 3.1e-06 26.8 0.7 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat PH_BEACH PF14844.1 GAM17883.1 - 3e-11 43.1 0.0 1.4e-10 40.9 0.0 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Peptidase_M20 PF01546.23 GAM17884.1 - 3.7e-30 104.8 0.0 4.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM17884.1 - 6.7e-21 74.1 0.0 1.2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM17884.1 - 0.08 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 G8 PF10162.4 GAM17885.1 - 5.9e-22 77.7 0.0 1.9e-21 76.1 0.0 2.0 1 0 0 1 1 1 1 G8 domain DUF4097 PF13349.1 GAM17885.1 - 0.003 17.1 1.6 0.012 15.2 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4097) KTI12 PF08433.5 GAM17886.1 - 2.3e-13 50.0 3.6 2.3e-13 50.0 2.5 1.7 1 1 1 2 2 2 1 Chromatin associated protein KTI12 DUF3458 PF11940.3 GAM17886.1 - 0.0036 16.1 0.1 0.0049 15.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) AAA_33 PF13671.1 GAM17886.1 - 0.051 13.4 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3994 PF13159.1 GAM17886.1 - 0.13 12.5 0.7 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Thiolase_N PF00108.18 GAM17887.1 - 1.3e-67 227.5 0.0 2e-67 226.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM17887.1 - 8e-46 154.4 0.5 1.8e-45 153.3 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM17887.1 - 0.00097 18.6 0.3 0.0039 16.6 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 GAM17887.1 - 0.011 15.6 0.2 0.035 14.1 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAM17887.1 - 0.047 13.3 2.4 0.86 9.2 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Prenylcys_lyase PF07156.9 GAM17887.1 - 0.051 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase EB PF01683.13 GAM17888.1 - 0.0026 17.7 10.8 0.0026 17.7 7.5 7.1 2 1 4 7 7 7 4 EB module FNIP PF05725.7 GAM17889.1 - 8e-28 96.1 25.8 1.8e-06 27.7 0.0 8.6 4 3 4 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 GAM17889.1 - 0.011 15.4 8.2 1.5 8.5 2.2 4.3 2 2 1 4 4 4 0 Leucine rich repeats (6 copies) PD40 PF07676.7 GAM17889.1 - 0.035 13.7 0.0 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat NLE PF08154.7 GAM17889.1 - 0.56 10.2 5.1 7.5 6.6 0.0 3.2 4 0 0 4 4 4 0 NLE (NUC135) domain DUF2576 PF10845.3 GAM17890.1 - 0.011 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) FimP PF09766.4 GAM17891.1 - 1.3e-51 175.7 20.0 1.3e-51 175.7 13.8 2.3 2 1 0 2 2 2 1 Fms-interacting protein EMP24_GP25L PF01105.19 GAM17892.1 - 9e-50 168.9 0.3 1.1e-49 168.6 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tox-ODYAM1 PF15642.1 GAM17892.1 - 0.057 12.0 0.1 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ATP_bind_3 PF01171.15 GAM17893.1 - 1.6e-40 138.5 0.0 2.8e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family QueC PF06508.8 GAM17893.1 - 0.0013 18.0 0.0 0.46 9.7 0.0 2.8 2 1 0 3 3 3 2 Queuosine biosynthesis protein QueC Ribosomal_S21e PF01249.13 GAM17895.1 - 3.9e-38 129.2 0.0 4.2e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Patatin PF01734.17 GAM17896.1 - 1.8e-18 67.2 0.3 1.2e-17 64.5 0.0 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase Sporozoite_P67 PF05642.6 GAM17896.1 - 0.0048 14.8 0.2 0.0048 14.8 0.1 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen FPN1 PF06963.7 GAM17897.1 - 1.4e-81 274.1 17.3 1.7e-81 273.8 12.0 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1_like PF12832.2 GAM17897.1 - 9.3e-05 22.1 3.3 9.3e-05 22.1 2.3 2.9 3 0 0 3 3 3 1 MFS_1 like family Cwf_Cwc_15 PF04889.7 GAM17897.1 - 3.9 7.1 7.8 6.8 6.3 5.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cation_ATPase_C PF00689.16 GAM17897.1 - 4.2 6.8 18.1 0.068 12.6 0.6 3.2 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus GATase_4 PF13230.1 GAM17898.1 - 6.8e-19 67.5 0.0 1.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAM17898.1 - 2.2e-10 40.6 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAM17898.1 - 4.6e-05 22.3 0.1 7e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Dicty_CTDC PF00526.13 GAM17899.1 - 0.0043 16.8 11.5 0.0043 16.8 8.0 20.5 19 5 0 19 19 19 6 Dictyostelium (slime mold) repeat OTU PF02338.14 GAM17900.1 - 2.5e-11 44.2 0.1 5.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 GAM17900.1 - 0.0012 19.0 1.3 0.0055 16.9 0.0 2.3 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.18 GAM17900.1 - 0.02 14.3 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family DUF3596 PF12167.3 GAM17900.1 - 0.084 12.4 0.1 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) GATA PF00320.22 GAM17901.1 - 5.3e-14 51.2 3.6 2.2e-13 49.3 2.5 2.1 1 0 0 1 1 1 1 GATA zinc finger RFX5_DNA_bdg PF14621.1 GAM17901.1 - 0.0076 15.8 0.7 0.0076 15.8 0.5 1.9 2 0 0 2 2 2 1 RFX5 DNA-binding domain Rod_cone_degen PF15201.1 GAM17902.1 - 0.16 11.8 1.5 0.36 10.6 1.0 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration Trypan_PARP PF05887.6 GAM17903.1 - 0.18 11.5 1.3 0.34 10.7 0.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.17 GAM17904.1 - 2.2e-50 170.2 0.3 2.5e-50 170.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM17904.1 - 1.8e-17 63.8 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM17904.1 - 2.6e-09 36.5 0.1 3.5e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM17904.1 - 2.3e-07 30.4 0.4 3.9e-07 29.6 0.2 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM17904.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3568 PF12092.3 GAM17904.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Cyclin PF08613.6 GAM17905.1 - 4.3e-30 105.0 0.0 5.7e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 GAM17905.1 - 1.8e-10 40.4 0.0 2.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WH2 PF02205.15 GAM17906.1 - 0.086 12.4 0.0 23 4.7 0.0 2.8 3 0 0 3 3 3 0 WH2 motif Sedlin_N PF04628.8 GAM17909.1 - 3.1e-47 159.7 1.4 3.5e-47 159.5 1.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAM17909.1 - 1.5e-09 37.7 1.2 7.4e-09 35.4 0.9 1.9 1 1 0 1 1 1 1 Sybindin-like family YecM PF06185.7 GAM17910.1 - 4.1e-17 62.0 0.1 6.2e-17 61.4 0.1 1.4 1 1 0 1 1 1 1 YecM protein FH2 PF02181.18 GAM17912.1 - 1.6e-95 320.1 4.2 2e-95 319.8 1.8 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAM17912.1 - 4.3e-30 104.4 0.7 1.8e-29 102.4 0.5 2.1 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAM17912.1 - 3.6e-21 75.4 3.3 3.6e-21 75.4 2.3 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain PRKCSH-like PF12999.2 GAM17913.1 - 1.3e-42 145.3 11.7 1.3e-42 145.3 8.1 2.6 1 1 3 4 4 4 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 GAM17913.1 - 1.3e-26 92.9 2.5 1.5e-26 92.7 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 GAM17913.1 - 0.00012 21.8 15.5 0.016 15.0 0.7 2.8 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH PF07915.8 GAM17913.1 - 0.011 16.5 0.5 0.011 16.5 0.4 2.9 2 2 0 2 2 2 0 Glucosidase II beta subunit-like protein SAPS PF04499.10 GAM17913.1 - 0.22 10.1 9.5 0.3 9.6 6.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EIIBC-GUT_N PF03612.9 GAM17913.1 - 0.35 10.4 3.4 6.3 6.3 3.1 2.5 2 1 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus V_ATPase_I PF01496.14 GAM17913.1 - 0.68 7.7 15.8 0.97 7.2 11.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.11 GAM17913.1 - 1.8 8.4 4.0 3.4 7.4 2.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3584 PF12128.3 GAM17913.1 - 2.2 5.5 25.9 2.8 5.1 17.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.1 GAM17913.1 - 4.6 6.1 19.4 8.9 5.1 13.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FNIP PF05725.7 GAM17914.1 - 7.1e-32 109.1 12.8 2.1e-10 40.3 0.1 4.9 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.7 GAM17915.1 - 4.7e-32 109.6 38.2 1.3e-11 44.2 1.6 6.6 2 2 5 8 8 8 8 FNIP Repeat FNIP PF05725.7 GAM17916.1 - 4.2e-47 157.8 23.6 4.8e-15 55.2 0.6 4.7 2 2 0 4 4 4 4 FNIP Repeat DUF1892 PF08987.5 GAM17916.1 - 0.067 13.2 0.8 0.11 12.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) LRR_5 PF13306.1 GAM17916.1 - 0.14 11.9 0.0 0.44 10.2 0.0 1.7 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) STAT2_C PF12188.3 GAM17916.1 - 0.17 11.7 1.8 2.2 8.1 0.2 2.8 3 0 0 3 3 3 0 Signal transducer and activator of transcription 2 C terminal TatD_DNase PF01026.16 GAM17918.1 - 3e-32 111.8 0.1 4.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase NUDIX PF00293.23 GAM17918.1 - 1.2e-19 70.3 0.1 2e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4211 PF13926.1 GAM17918.1 - 0.018 14.4 0.2 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) FNIP PF05725.7 GAM17919.1 - 6e-29 99.7 25.6 2.6e-08 33.6 0.4 7.2 5 2 3 8 8 8 7 FNIP Repeat PS_Dcarbxylase PF02666.10 GAM17920.1 - 1.7e-53 180.9 0.1 2.7e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 GAM17920.1 - 1.1e-22 79.7 0.1 2e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_5 PF13202.1 GAM17920.1 - 2.9e-06 26.3 0.2 7.3e-06 25.0 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 GAM17920.1 - 6.6e-06 25.0 0.2 2.2e-05 23.4 0.1 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAM17920.1 - 2.5e-05 24.3 0.2 0.00014 21.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM17920.1 - 0.0012 18.4 0.1 0.0037 16.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM17920.1 - 0.0049 16.6 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF1191 PF06697.7 GAM17921.1 - 0.0059 15.4 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 GAM17921.1 - 0.01 16.2 0.1 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 GAM17921.1 - 0.034 14.3 0.1 0.053 13.7 0.1 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family TMEM154 PF15102.1 GAM17921.1 - 0.045 13.4 0.2 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Beta-APP PF03494.8 GAM17921.1 - 1.8 8.0 5.2 0.68 9.4 1.4 1.9 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Syndecan PF01034.15 GAM17921.1 - 7 6.3 6.1 30 4.3 4.2 2.0 1 1 0 1 1 1 0 Syndecan domain DSPc PF00782.15 GAM17922.1 - 7e-31 106.5 3.5 1.9e-30 105.1 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 GAM17922.1 - 6.2e-18 64.0 22.1 3.7e-07 29.6 0.4 5.7 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM17922.1 - 6.3e-14 51.4 24.3 1.2e-07 31.3 0.4 5.7 3 1 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 GAM17922.1 - 7.8e-11 40.4 27.4 0.77 10.0 0.1 9.4 9 0 0 9 9 9 5 Leucine Rich Repeat Y_phosphatase PF00102.22 GAM17922.1 - 0.00046 19.5 6.2 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase LRR_9 PF14580.1 GAM17922.1 - 0.005 16.4 1.0 0.14 11.6 0.2 2.3 1 1 1 2 2 2 1 Leucine-rich repeat Pkinase PF00069.20 GAM17923.1 - 2e-28 99.2 0.0 3.3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17923.1 - 3.6e-21 75.4 0.0 1.5e-20 73.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAM17923.1 - 0.0047 15.7 0.0 0.008 15.0 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 GAM17924.1 - 7.5e-63 212.0 0.0 7.5e-63 212.0 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17924.1 - 1.4e-45 155.4 0.0 1.4e-45 155.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM17924.1 - 0.0015 18.3 0.0 0.0086 15.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Med15 PF09606.5 GAM17924.1 - 0.013 13.7 28.3 0.0083 14.3 14.6 2.2 2 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Seadorna_VP7 PF07387.6 GAM17924.1 - 0.018 13.8 0.3 0.037 12.8 0.2 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PAT1 PF09770.4 GAM17924.1 - 0.044 12.0 21.4 0.071 11.3 14.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cyclase_polyket PF04673.7 GAM17924.1 - 0.27 11.2 4.0 0.66 10.0 2.8 1.6 1 0 0 1 1 1 0 Polyketide synthesis cyclase BAF1_ABF1 PF04684.8 GAM17924.1 - 0.31 9.8 17.9 0.52 9.1 12.4 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAS_11 PF14598.1 GAM17924.1 - 0.87 9.5 14.4 2 8.3 10.0 1.6 1 0 0 1 1 1 0 PAS domain PIP5K PF01504.13 GAM17926.1 - 5.5e-58 196.0 0.5 1.1e-57 195.0 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 GAM17926.1 - 2.6e-20 72.5 0.1 1.2e-19 70.3 0.1 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 GAM17926.1 - 8.1e-19 67.3 7.3 2.4e-18 65.7 5.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger HlyD_3 PF13437.1 GAM17926.1 - 0.012 15.9 2.5 0.061 13.6 0.0 2.9 3 0 0 3 3 3 0 HlyD family secretion protein IBR PF01485.16 GAM17926.1 - 2.9 7.8 11.9 0.036 13.9 2.5 2.1 2 0 0 2 2 2 0 IBR domain DUF4150 PF13665.1 GAM17927.1 - 0.28 11.0 5.4 0.81 9.6 2.2 2.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4150) Glyco_hydro_2 PF00703.16 GAM17928.1 - 4.5e-06 27.0 1.4 1.4e-05 25.4 0.0 2.6 4 0 0 4 4 4 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 GAM17928.1 - 0.0002 20.9 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 GAM17928.1 - 0.056 12.3 0.2 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 GAM17929.1 - 4.6e-49 166.8 0.1 5.4e-30 104.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17929.1 - 2.4e-18 66.1 0.1 2.4e-14 53.0 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM17929.1 - 0.045 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 GAM17929.1 - 0.12 11.7 0.1 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Dicty_REP PF05086.7 GAM17929.1 - 0.2 9.3 11.2 0.0043 14.9 1.2 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DDHD PF02862.12 GAM17929.1 - 0.23 11.2 10.4 0.97 9.1 0.7 2.3 2 0 0 2 2 2 0 DDHD domain DUF1499 PF07386.6 GAM17929.1 - 0.34 11.0 7.7 0.16 12.1 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1499) FAM220 PF15487.1 GAM17929.1 - 0.45 9.8 13.2 0.23 10.8 4.1 2.5 2 0 0 2 2 2 0 FAM220 family YchF-GTPase_C PF06071.8 GAM17929.1 - 0.53 10.1 3.0 0.63 9.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF933) PP2C_2 PF13672.1 GAM17930.1 - 4.5e-06 26.2 0.0 9.8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 GAM17930.1 - 0.0092 15.4 0.0 0.04 13.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM17930.1 - 0.023 14.4 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DUF2112 PF09885.4 GAM17930.1 - 0.041 13.5 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Myb_DNA-bind_4 PF13837.1 GAM17930.1 - 0.065 13.3 0.3 0.065 13.3 0.2 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Clat_adaptor_s PF01217.15 GAM17931.1 - 3.3e-48 163.0 5.6 3.8e-48 162.8 3.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 GAM17931.1 - 0.0035 17.3 0.1 0.0042 17.0 0.1 1.3 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 AAA_23 PF13476.1 GAM17932.1 - 0.016 15.5 2.5 0.02 15.2 1.7 1.2 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 GAM17932.1 - 0.2 11.3 8.6 0.25 11.0 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PqqA PF08042.6 GAM17932.1 - 0.28 10.8 1.0 0.46 10.2 0.7 1.4 1 0 0 1 1 1 0 PqqA family Gag_spuma PF03276.9 GAM17932.1 - 0.38 9.0 15.5 0.5 8.6 10.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein CPSF100_C PF13299.1 GAM17932.1 - 1.4 9.0 9.9 2.2 8.4 6.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.3 GAM17932.1 - 2.3 6.6 9.9 3.1 6.3 6.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.12 GAM17932.1 - 2.7 6.7 4.5 3.7 6.2 3.1 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.8 GAM17932.1 - 3.1 7.6 22.7 4.5 7.0 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 GAM17932.1 - 5.2 5.1 28.1 6.4 4.8 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 GAM17934.1 - 6.3e-17 61.3 20.7 3.1e-14 52.4 14.2 2.2 1 1 0 1 1 1 1 LMBR1-like membrane protein TarH PF02203.10 GAM17934.1 - 0.01 15.6 1.4 0.01 15.6 1.0 2.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue PilX_N PF14341.1 GAM17934.1 - 0.032 13.8 0.9 0.17 11.6 0.6 2.4 1 0 0 1 1 1 0 PilX N-terminal Anophelin PF10731.4 GAM17934.1 - 0.23 11.5 3.4 0.22 11.6 0.2 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Cytochrom_B561 PF03188.11 GAM17934.1 - 9.1 6.1 10.8 0.37 10.6 1.4 3.2 3 1 0 3 3 3 0 Eukaryotic cytochrome b561 BTB_2 PF02214.17 GAM17935.1 - 7.7e-16 58.0 0.0 1.8e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Aminotran_1_2 PF00155.16 GAM17936.1 - 1.8e-58 198.2 0.0 2e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAM17936.1 - 0.00053 18.8 0.1 0.0046 15.7 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM17936.1 - 0.00086 18.5 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 GAM17936.1 - 0.0035 15.6 0.0 0.008 14.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAM17936.1 - 0.074 12.0 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 GAM17937.1 - 5e-192 638.2 0.6 1.2e-180 600.7 0.0 3.2 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 GAM17937.1 - 1.9e-06 26.8 0.4 1.1e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM17937.1 - 9e-05 21.7 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase FNIP PF05725.7 GAM17938.1 - 5.5e-43 144.6 24.1 6.1e-12 45.3 1.3 8.6 6 1 2 9 9 9 7 FNIP Repeat 5_nucleotid PF05761.9 GAM17939.1 - 3.4e-52 177.4 1.2 4.6e-52 177.0 0.3 1.5 1 1 1 2 2 2 1 5' nucleotidase family DUF1910 PF08928.5 GAM17939.1 - 0.02 14.9 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) HAD_2 PF13419.1 GAM17939.1 - 0.021 15.0 0.1 0.09 12.9 0.0 2.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF43 PF01861.11 GAM17939.1 - 0.16 10.9 0.5 0.53 9.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF43 FH2 PF02181.18 GAM17940.1 - 1.5e-68 231.3 1.0 5.9e-68 229.4 0.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAM17940.1 - 3e-07 29.9 0.1 8.4e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF3361 PF11841.3 GAM17940.1 - 0.00012 21.8 0.3 0.0009 18.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Arm PF00514.18 GAM17940.1 - 0.14 12.0 0.7 13 5.8 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat EF-hand_1 PF00036.27 GAM17941.1 - 5e-20 69.2 4.0 7.3e-06 24.9 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 GAM17941.1 - 1.8e-19 69.6 12.3 1.8e-10 40.7 0.7 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM17941.1 - 1e-17 62.5 5.7 6.8e-07 28.3 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAM17941.1 - 2.3e-17 61.2 4.0 0.00015 21.3 0.0 4.9 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAM17941.1 - 3.1e-10 39.4 6.2 0.0062 16.1 0.2 3.9 3 1 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM17941.1 - 2.9e-05 24.0 0.2 0.93 9.5 0.0 3.5 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAM17941.1 - 3.3e-05 23.5 0.3 0.13 11.9 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand HCaRG PF07258.9 GAM17941.1 - 0.026 14.0 0.1 0.13 11.8 0.0 2.1 2 1 0 2 2 2 0 HCaRG protein Cir_Bir_Yir PF06022.6 GAM17941.1 - 0.22 10.7 2.9 0.36 10.0 2.0 1.3 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Catalase PF00199.14 GAM17942.1 - 3.8e-191 634.8 0.4 4.4e-191 634.5 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAM17942.1 - 5.1e-23 80.7 0.1 1.4e-22 79.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Peptidase_M16_C PF05193.16 GAM17943.1 - 1.1e-18 67.6 0.0 1.2e-10 41.3 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM17943.1 - 1.3e-09 37.9 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 GAM17943.1 - 0.036 12.9 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16C associated CobT PF06213.7 GAM17943.1 - 1.1 8.2 15.1 1.9 7.5 10.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3439 PF11921.3 GAM17943.1 - 6.2 6.5 8.6 0.38 10.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CDC45 PF02724.9 GAM17943.1 - 6.6 4.6 8.0 9.9 4.0 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_1 PF00583.19 GAM17944.1 - 1.1e-16 60.5 0.0 1.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM17944.1 - 1.5e-09 37.9 0.2 2.5e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM17944.1 - 2.9e-07 30.6 0.0 3.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM17944.1 - 2.5e-06 27.5 0.0 3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM17944.1 - 3.7e-05 23.5 0.0 6.5e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM17944.1 - 4.4e-05 23.6 0.0 7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM17944.1 - 6.2e-05 22.6 0.0 0.00014 21.5 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 GAM17944.1 - 0.00047 19.9 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 GAM17944.1 - 0.0091 15.8 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NMT_C PF02799.10 GAM17944.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain adh_short PF00106.20 GAM17945.1 - 6.2e-26 91.2 0.1 1.3e-25 90.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM17945.1 - 4.6e-15 56.0 0.0 6.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM17945.1 - 1.4e-08 34.2 0.0 1.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM17945.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM17945.1 - 4.3e-05 23.5 0.0 7.6e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM17945.1 - 0.0016 17.9 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM17945.1 - 0.0034 16.3 0.0 0.0057 15.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 GAM17945.1 - 0.068 12.9 0.4 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAM17945.1 - 0.092 11.8 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_26 PF13500.1 GAM17945.1 - 0.16 11.5 1.0 0.84 9.1 0.3 2.1 1 1 0 2 2 2 0 AAA domain Lipase_GDSL PF00657.17 GAM17946.1 - 4.2e-10 39.8 0.0 8.5e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 GAM17946.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FtsX PF02687.16 GAM17947.1 - 6.9e-30 103.3 38.4 1.7e-16 60.0 10.2 4.9 4 1 1 5 5 5 2 FtsX-like permease family MacB_PCD PF12704.2 GAM17947.1 - 1.2e-09 38.1 3.6 1.1e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 MacB-like periplasmic core domain tRNA-synt_1d PF00750.14 GAM17948.1 - 8.4e-64 215.6 0.0 1.5e-60 204.9 0.0 2.5 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 GAM17948.1 - 5.8e-22 77.8 0.0 6.1e-21 74.5 0.0 2.5 2 1 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 GAM17948.1 - 6.3e-05 23.4 0.0 0.0026 18.2 0.0 3.2 4 0 0 4 4 4 1 Arginyl tRNA synthetase N terminal domain TRAM PF01938.15 GAM17948.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 TRAM domain tRNA-synt_1 PF00133.17 GAM17948.1 - 0.074 11.0 0.0 0.42 8.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) PTEN_C2 PF10409.4 GAM17949.1 - 1.8e-19 69.8 0.1 8.1e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein PH PF00169.24 GAM17949.1 - 2.8e-19 69.2 0.1 1.4e-18 67.0 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM17949.1 - 1.9e-08 34.5 5.9 2.1e-07 31.1 0.4 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.1 GAM17949.1 - 1.3e-06 28.3 0.0 4.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Y_phosphatase PF00102.22 GAM17949.1 - 1.3e-05 24.6 0.2 6.3e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM17949.1 - 3.5e-05 24.1 0.9 0.00014 22.1 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 GAM17949.1 - 4.6e-05 23.0 0.8 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PH_3 PF14593.1 GAM17949.1 - 0.0012 18.7 0.5 0.004 17.0 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 GAM17949.1 - 0.0036 17.4 0.2 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain CDKN3 PF05706.7 GAM17949.1 - 0.0054 16.1 0.1 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 GAM17949.1 - 0.016 15.2 0.8 0.095 12.7 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 GAM17949.1 - 1.1 8.5 4.4 1.3 8.4 0.0 2.9 3 1 0 3 3 3 0 Tyrosine phosphatase family SRPRB PF09439.5 GAM17950.1 - 2.9e-34 117.8 0.0 3.6e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 GAM17950.1 - 3e-17 62.3 0.0 4e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM17950.1 - 4.4e-08 32.7 0.0 2.5e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM17950.1 - 1.1e-06 27.9 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM17950.1 - 1.7e-06 27.0 1.1 0.0014 17.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 GAM17950.1 - 4.4e-06 27.1 0.0 7.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM17950.1 - 3.1e-05 23.8 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 GAM17950.1 - 3.9e-05 23.1 0.0 5.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 GAM17950.1 - 0.00021 20.5 0.0 0.00031 20.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 GAM17950.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 GAM17950.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SecG PF03840.9 GAM17950.1 - 0.16 11.7 3.7 0.27 11.0 2.6 1.4 1 0 0 1 1 1 0 Preprotein translocase SecG subunit zf-DHHC PF01529.15 GAM17951.1 - 4.3e-39 133.6 0.5 5.4e-39 133.3 0.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase FtsX PF02687.16 GAM17951.1 - 0.0037 16.9 0.4 0.61 9.8 0.2 2.1 1 1 1 2 2 2 2 FtsX-like permease family DNA_pol_E_B PF04042.11 GAM17951.1 - 0.073 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Claudin_3 PF06653.6 GAM17951.1 - 2.3 7.9 6.3 1.4 8.6 1.3 2.4 2 1 0 2 2 2 0 Tight junction protein, Claudin-like VMA21 PF09446.5 GAM17952.1 - 7e-12 45.1 5.8 7e-12 45.1 4.0 1.5 2 0 0 2 2 2 1 VMA21-like domain GET2 PF08690.5 GAM17952.1 - 0.00039 19.7 4.8 0.0005 19.4 3.3 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 TFIIF_alpha PF05793.7 GAM17952.1 - 0.0024 16.3 11.6 0.0028 16.1 8.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRP PF06011.7 GAM17952.1 - 0.013 14.0 0.6 0.013 14.0 0.4 2.0 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel PMP22_Claudin PF00822.15 GAM17952.1 - 0.018 14.7 0.7 0.036 13.7 0.5 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family ORC6 PF05460.8 GAM17952.1 - 0.02 13.9 6.6 0.027 13.5 4.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Tir_receptor_N PF07490.6 GAM17952.1 - 0.048 13.2 2.6 0.066 12.8 1.8 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus DUF572 PF04502.8 GAM17952.1 - 0.067 12.3 10.5 0.079 12.1 7.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PqiA PF04403.8 GAM17952.1 - 0.12 11.9 1.4 0.2 11.2 1.0 1.2 1 0 0 1 1 1 0 Paraquat-inducible protein A FAM60A PF15396.1 GAM17952.1 - 0.18 11.5 6.0 0.23 11.2 4.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.1 GAM17952.1 - 0.32 10.4 15.6 0.53 9.7 10.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO BTV_NS2 PF04514.7 GAM17952.1 - 2.7 6.8 9.0 3.4 6.4 6.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BIV_Env PF05858.7 GAM17952.1 - 4.5 5.1 5.4 7.4 4.3 3.7 1.3 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) CTI PF06934.6 GAM17952.1 - 7.1 4.7 9.3 9.5 4.3 6.5 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) RhoGAP PF00620.22 GAM17953.1 - 1.5e-06 27.9 0.1 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain WD40 PF00400.27 GAM17954.1 - 1.6e-11 43.6 9.2 0.0016 18.2 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 GAM17954.1 - 1.9e-05 24.4 0.3 0.48 10.1 0.0 3.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A GST_C PF00043.20 GAM17955.1 - 4.6e-14 52.1 0.1 8.2e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM17955.1 - 7.7e-10 38.8 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM17955.1 - 2.8e-09 36.7 0.3 8e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM17955.1 - 5.7e-09 35.8 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM17955.1 - 2.1e-08 34.2 0.0 4.8e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM17955.1 - 5.2e-07 30.0 0.1 7.6e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BSD PF03909.12 GAM17956.1 - 3.7e-07 29.7 0.3 8.4e-07 28.6 0.2 1.6 1 0 0 1 1 1 1 BSD domain SAP30_Sin3_bdg PF13867.1 GAM17957.1 - 1.7e-20 72.6 0.2 2.9e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Suc_Fer-like PF06999.7 GAM17958.1 - 4.2e-36 125.1 0.0 8.5e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2_2 PF01799.15 GAM17958.1 - 0.0041 16.9 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 2 [2Fe-2S] binding domain DEC-1_N PF04625.8 GAM17958.1 - 0.029 13.0 9.6 0.044 12.4 6.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Guanylate_cyc_2 PF09778.4 GAM17958.1 - 0.095 11.8 0.0 4.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Guanylylate cyclase TSGP1 PF07771.6 GAM17958.1 - 2.1 8.2 7.9 4.6 7.1 5.5 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Lactamase_B_2 PF12706.2 GAM17960.1 - 4.2e-40 137.3 1.2 6.4e-40 136.7 0.8 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM17960.1 - 6.7e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HRM PF02793.17 GAM17960.1 - 0.0058 16.6 4.2 0.012 15.6 2.9 1.4 1 0 0 1 1 1 1 Hormone receptor domain OTU PF02338.14 GAM17961.1 - 9.6e-18 64.9 0.5 2.6e-17 63.5 0.3 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease APC_CDC26 PF10471.4 GAM17961.1 - 0.2 12.4 6.1 0.18 12.5 0.3 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 MS_channel PF00924.13 GAM17962.1 - 2.9e-19 69.2 0.5 8.3e-19 67.7 0.3 1.8 1 0 0 1 1 1 1 Mechanosensitive ion channel EVI2A PF05399.6 GAM17962.1 - 0.0014 17.9 0.8 0.0025 17.0 0.5 1.4 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF2839 PF10999.3 GAM17962.1 - 0.27 11.2 1.5 4.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) WD40 PF00400.27 GAM17964.1 - 4.7e-43 143.5 21.8 6.5e-09 35.3 1.7 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat YmzC PF14157.1 GAM17964.1 - 0.00039 20.1 0.0 3.3 7.5 0.0 4.2 4 0 0 4 4 4 1 YmzC-like protein Nup160 PF11715.3 GAM17964.1 - 0.046 11.8 3.9 0.41 8.7 0.1 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF1713 PF08213.6 GAM17965.1 - 2.4e-09 36.6 18.4 3.5e-09 36.1 12.8 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Nuf2 PF03800.9 GAM17966.1 - 1.4e-31 109.4 0.5 1.4e-31 109.4 0.4 2.1 2 0 0 2 2 2 1 Nuf2 family SlyX PF04102.7 GAM17966.1 - 0.014 15.7 4.1 0.014 15.7 2.8 4.9 3 1 3 6 6 6 0 SlyX DUF2325 PF10087.4 GAM17966.1 - 0.077 12.8 1.9 0.1 12.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Myosin_tail_1 PF01576.14 GAM17966.1 - 0.082 10.6 50.3 0.23 9.1 15.5 2.3 1 1 1 2 2 2 0 Myosin tail WEMBL PF05701.6 GAM17966.1 - 0.099 11.0 35.6 0.15 10.4 24.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light ADIP PF11559.3 GAM17966.1 - 0.14 12.0 43.7 0.19 11.6 4.5 4.3 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 GAM17966.1 - 0.23 11.2 29.5 2 8.1 2.4 3.5 1 1 2 3 3 3 0 Laminin Domain II Reo_sigmaC PF04582.7 GAM17966.1 - 0.88 8.6 7.8 2.9 6.9 0.5 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein YjcZ PF13990.1 GAM17966.1 - 0.97 8.5 11.5 2 7.5 2.1 2.7 1 1 1 2 2 2 0 YjcZ-like protein APG6 PF04111.7 GAM17966.1 - 1 8.3 44.1 0.033 13.2 4.0 2.9 2 1 1 3 3 3 0 Autophagy protein Apg6 DUF4463 PF14703.1 GAM17966.1 - 1.2 9.7 8.9 0.23 11.9 2.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) GLE1 PF07817.8 GAM17966.1 - 5.8 5.7 15.8 1.5 7.7 0.5 2.6 1 1 0 2 2 2 0 GLE1-like protein Spc7 PF08317.6 GAM17966.1 - 6.7 5.2 47.6 0.54 8.8 9.9 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein IFT57 PF10498.4 GAM17966.1 - 8 5.0 39.9 0.67 8.6 4.7 3.2 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Ank_2 PF12796.2 GAM17967.1 - 2e-36 124.1 3.7 6.3e-12 45.6 0.0 5.1 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM17967.1 - 3.6e-33 113.3 9.8 6.6e-08 32.8 0.1 8.4 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM17967.1 - 3.4e-30 103.3 12.2 0.005 17.0 0.0 10.9 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM17967.1 - 4.6e-22 75.9 8.3 0.2 12.0 0.0 11.2 7 3 5 12 12 12 7 Ankyrin repeat Ank PF00023.25 GAM17967.1 - 7.4e-18 63.3 5.2 0.21 11.4 0.0 11.1 10 1 1 11 11 11 3 Ankyrin repeat zf-Tim10_DDP PF02953.10 GAM17967.1 - 0.079 12.2 0.3 8.5 5.7 0.0 2.7 2 0 0 2 2 2 0 Tim10/DDP family zinc finger DUF4031 PF13223.1 GAM17967.1 - 0.24 11.5 1.8 12 6.1 0.1 3.4 4 1 1 5 5 5 0 Protein of unknown function (DUF4031) RIO1 PF01163.17 GAM17968.1 - 2.6e-48 163.8 0.2 2.6e-48 163.8 0.2 2.0 2 1 0 2 2 2 1 RIO1 family Rio2_N PF09202.6 GAM17968.1 - 8.7e-31 105.8 0.1 2.4e-30 104.4 0.1 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 GAM17968.1 - 1.1e-09 38.3 0.2 5.9e-05 22.9 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM17968.1 - 1.5e-07 30.6 0.4 1.5e-06 27.4 0.0 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 GAM17968.1 - 2.2e-05 23.7 0.1 2.2e-05 23.7 0.1 1.9 3 0 0 3 3 3 1 Protein kinase domain Kinase-like PF14531.1 GAM17968.1 - 0.015 14.2 0.0 0.08 11.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Glyco_transf_15 PF01793.11 GAM17968.1 - 5.3 5.8 14.1 11 4.8 9.5 1.7 1 1 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase LRR_6 PF13516.1 GAM17969.1 - 2.8e-07 29.9 4.4 0.41 10.8 0.1 5.0 4 1 1 5 5 5 2 Leucine Rich repeat F-box PF00646.28 GAM17969.1 - 0.0003 20.3 1.5 0.00057 19.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 GAM17969.1 - 0.0032 17.0 3.9 1.4 8.6 0.1 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 GAM17969.1 - 0.0053 16.4 1.0 0.011 15.4 0.2 1.9 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.8 GAM17969.1 - 0.0072 16.7 0.0 2.1 8.9 0.0 3.6 2 0 0 2 2 2 1 Leucine Rich Repeat FNIP PF05725.7 GAM17969.1 - 0.13 12.2 0.7 0.67 9.9 0.0 2.8 4 1 0 4 4 4 0 FNIP Repeat LRR_7 PF13504.1 GAM17969.1 - 5 7.7 9.8 46 4.8 0.1 5.3 7 0 0 7 7 7 0 Leucine rich repeat Peptidase_M49 PF03571.10 GAM17970.1 - 3.8e-216 718.4 0.0 4.8e-216 718.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 ERG4_ERG24 PF01222.12 GAM17971.1 - 1.1e-128 429.5 19.2 1.3e-128 429.2 13.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAM17971.1 - 0.0012 18.2 1.6 0.0012 18.2 1.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) HA PF03457.9 GAM17971.1 - 0.13 12.3 0.2 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Helicase associated domain Yippee-Mis18 PF03226.9 GAM17972.1 - 1.4e-15 57.1 3.0 1.5e-15 56.9 2.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MIP-T3 PF10243.4 GAM17973.1 - 1.8e-08 33.3 47.0 1.1e-05 24.0 6.0 2.5 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 GAM17973.1 - 2e-08 33.7 0.1 4.5e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM17973.1 - 2.1e-08 34.0 0.1 5.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM17973.1 - 1.1e-07 31.6 0.3 3.7e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 GAM17973.1 - 0.00026 21.0 2.1 0.00069 19.6 0.1 2.7 2 0 0 2 2 2 1 PWI domain Nup35_RRM_2 PF14605.1 GAM17973.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HSP20 PF00011.16 GAM17974.1 - 3.9e-14 52.3 1.1 7.7e-14 51.4 0.8 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 GAM17974.1 - 0.0015 18.9 4.3 0.0031 18.0 0.6 2.3 2 0 0 2 2 2 1 CS domain PilJ PF13675.1 GAM17974.1 - 0.065 13.5 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4304 PF14137.1 GAM17974.1 - 0.65 10.1 5.0 0.86 9.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4304) MRP-L46 PF11788.3 GAM17974.1 - 1 10.0 5.7 0.37 11.4 1.0 1.9 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 DUF747 PF05346.6 GAM17975.1 - 3.1e-103 345.3 13.8 4.1e-103 344.9 9.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family PMP1_2 PF08114.6 GAM17975.1 - 1.6 8.2 5.3 3.7 7.1 3.7 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Cyclin PF08613.6 GAM17976.1 - 5.2e-22 78.8 3.4 5.2e-22 78.8 2.3 3.5 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.18 GAM17976.1 - 1.2e-07 31.3 0.1 1.2e-07 31.3 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain SOBP PF15279.1 GAM17976.1 - 0.052 13.9 49.4 0.31 11.3 10.9 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DUF3546 PF12066.3 GAM17977.1 - 4.7e-22 78.0 7.5 4.7e-22 78.0 5.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 GAM17977.1 - 3.7e-15 56.6 0.3 3.7e-15 56.6 0.2 2.8 2 1 1 3 3 3 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 GAM17977.1 - 4.4e-13 48.6 0.2 1.2e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.17 GAM17977.1 - 5.2e-06 26.0 0.0 1.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.2 GAM17977.1 - 0.0033 17.4 2.0 0.0033 17.4 1.4 3.1 3 1 0 3 3 3 1 C2H2 type zinc-finger (2 copies) RRM_6 PF14259.1 GAM17977.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 GAM17977.1 - 0.14 12.5 1.8 0.24 11.8 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger UQ_con PF00179.21 GAM17978.1 - 1.3e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM17978.1 - 1.9e-05 24.4 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM17978.1 - 0.011 15.6 0.2 0.016 15.0 0.1 1.5 1 1 0 1 1 1 0 RWD domain AAA_5 PF07728.9 GAM17979.1 - 8.4e-119 391.6 0.0 1.3e-22 80.0 0.0 8.5 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM17979.1 - 4.7e-32 110.3 0.0 3.3e-11 42.9 0.0 7.0 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 GAM17979.1 - 1.1e-24 87.0 0.8 5.8e-05 23.3 0.0 7.2 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM17979.1 - 8.9e-21 74.7 6.7 0.00019 21.4 0.0 6.5 6 1 0 6 6 5 4 AAA ATPase domain AAA_14 PF13173.1 GAM17979.1 - 9.1e-21 74.0 0.0 0.00016 21.5 0.0 6.8 7 0 0 7 7 7 4 AAA domain AAA_22 PF13401.1 GAM17979.1 - 2.4e-19 69.7 0.3 0.0044 17.1 0.0 7.3 6 1 0 6 6 6 3 AAA domain AAA_17 PF13207.1 GAM17979.1 - 1.5e-17 64.5 0.0 0.017 15.9 0.0 6.7 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.21 GAM17979.1 - 2.6e-16 59.5 0.1 0.0082 15.6 0.0 6.0 5 1 0 5 5 5 3 Sigma-54 interaction domain Zeta_toxin PF06414.7 GAM17979.1 - 2.1e-15 56.3 0.2 0.00012 21.2 0.0 4.9 5 0 0 5 5 4 4 Zeta toxin AAA_18 PF13238.1 GAM17979.1 - 1.5e-14 54.4 0.3 0.11 12.8 0.0 6.1 5 0 0 5 5 5 4 AAA domain AAA_33 PF13671.1 GAM17979.1 - 1e-13 51.3 0.0 0.079 12.8 0.0 6.4 6 1 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.1 GAM17979.1 - 2.9e-12 46.8 0.0 0.024 14.6 0.0 6.0 5 0 0 5 5 5 2 Sigma-54 interaction domain T2SE PF00437.15 GAM17979.1 - 6.4e-12 44.9 10.5 0.022 13.6 0.0 6.0 6 0 0 6 6 6 3 Type II/IV secretion system protein ABC_tran PF00005.22 GAM17979.1 - 4.4e-11 43.2 3.0 0.035 14.4 0.0 5.7 5 0 0 5 5 5 2 ABC transporter UPF0079 PF02367.12 GAM17979.1 - 2.9e-10 39.8 1.1 0.43 10.2 0.0 5.6 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 GAM17979.1 - 1.1e-09 38.7 1.2 0.47 10.9 0.0 5.4 6 0 0 6 6 4 2 Miro-like protein NACHT PF05729.7 GAM17979.1 - 1.3e-09 37.8 1.7 0.3 10.7 0.0 5.7 6 0 0 6 6 6 3 NACHT domain AAA_19 PF13245.1 GAM17979.1 - 2e-09 37.0 4.0 0.69 9.7 0.1 5.8 6 0 0 6 6 5 3 Part of AAA domain RNA_helicase PF00910.17 GAM17979.1 - 4.7e-09 36.3 0.2 0.21 11.7 0.0 5.7 5 0 0 5 5 5 1 RNA helicase AAA_30 PF13604.1 GAM17979.1 - 1.5e-08 34.4 0.0 0.86 9.1 0.0 6.1 6 0 0 6 6 5 1 AAA domain AAA_29 PF13555.1 GAM17979.1 - 2.6e-08 33.2 0.2 6.1 6.4 0.0 5.7 5 0 0 5 5 5 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 GAM17979.1 - 2.7e-08 33.8 1.7 0.041 13.5 0.1 4.8 4 0 0 4 4 4 1 Archaeal ATPase Mg_chelatase PF01078.16 GAM17979.1 - 2.8e-08 33.1 0.1 6.3 5.9 0.0 8.0 10 0 0 10 10 9 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 GAM17979.1 - 3.7e-08 32.6 0.5 0.17 10.7 0.0 4.9 5 0 0 5 5 5 2 Protein of unknown function (DUF815) DUF258 PF03193.11 GAM17979.1 - 4.4e-08 32.4 3.0 0.57 9.3 0.0 5.1 6 0 0 6 6 5 3 Protein of unknown function, DUF258 AAA_28 PF13521.1 GAM17979.1 - 4.5e-08 33.2 3.9 0.45 10.4 0.0 5.2 5 0 0 5 5 5 3 AAA domain IstB_IS21 PF01695.12 GAM17979.1 - 5.1e-08 32.5 0.7 0.18 11.2 0.0 5.9 6 0 0 6 6 6 1 IstB-like ATP binding protein MobB PF03205.9 GAM17979.1 - 2.4e-07 30.5 0.3 2.1 8.0 0.0 5.7 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 GAM17979.1 - 6.1e-07 29.0 4.7 1.2 8.6 0.0 5.9 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 GAM17979.1 - 7.4e-07 28.7 1.7 0.18 11.1 0.0 5.3 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain cobW PF02492.14 GAM17979.1 - 2.1e-06 27.2 1.6 0.33 10.3 0.1 4.3 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 GAM17979.1 - 2.3e-06 28.0 7.5 0.95 9.7 0.0 6.0 6 1 0 6 6 5 2 AAA domain RuvB_N PF05496.7 GAM17979.1 - 1.4e-05 24.2 2.9 0.88 8.5 0.0 5.9 6 1 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 GAM17979.1 - 1.6e-05 24.1 0.0 1.1 8.2 0.0 4.3 4 0 0 4 4 4 2 KAP family P-loop domain AAA_11 PF13086.1 GAM17979.1 - 2e-05 24.2 0.3 3 7.3 0.0 5.2 6 0 0 6 6 5 0 AAA domain KaiC PF06745.8 GAM17979.1 - 4.9e-05 22.5 1.9 2.9 6.9 0.0 4.9 5 0 0 5 5 5 0 KaiC AAA_25 PF13481.1 GAM17979.1 - 6.4e-05 22.4 0.2 1.5 8.1 0.0 5.0 5 0 0 5 5 5 1 AAA domain MMR_HSR1 PF01926.18 GAM17979.1 - 0.0001 22.2 0.4 3.9 7.4 0.0 4.6 4 0 0 4 4 4 0 50S ribosome-binding GTPase TIP49 PF06068.8 GAM17979.1 - 0.00011 21.1 1.4 0.13 10.9 0.0 3.6 4 0 0 4 4 4 1 TIP49 C-terminus ATP-synt_ab PF00006.20 GAM17979.1 - 0.00011 21.7 0.0 8 5.8 0.0 4.2 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 GAM17979.1 - 0.00012 21.7 0.0 1.3 8.4 0.0 4.1 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase CPT PF07931.7 GAM17979.1 - 0.0002 21.0 2.5 4.8 6.7 0.0 6.1 6 1 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 GAM17979.1 - 0.00029 20.7 4.2 0.095 12.5 0.1 4.7 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 GAM17979.1 - 0.00039 20.1 3.9 2.7 7.6 0.0 4.8 4 0 0 4 4 4 0 NTPase DUF2075 PF09848.4 GAM17979.1 - 0.0028 16.6 0.8 11 4.9 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 GAM17979.1 - 0.0031 16.2 0.7 4.8 5.6 0.0 4.1 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.2 GAM17979.1 - 0.0039 16.3 0.1 1.1 8.3 0.0 3.5 4 0 0 4 4 4 1 P-loop containing dynein motor region D3 Thymidylate_kin PF02223.12 GAM17979.1 - 0.0061 15.9 0.9 2.3 7.5 0.0 3.8 4 0 0 4 4 3 1 Thymidylate kinase MCM PF00493.18 GAM17979.1 - 0.0096 14.7 0.1 7.3 5.2 0.0 4.4 5 0 0 5 5 5 0 MCM2/3/5 family IPT PF01745.11 GAM17979.1 - 0.011 14.9 0.2 29 3.7 0.0 4.0 4 0 0 4 4 4 0 Isopentenyl transferase AAA_24 PF13479.1 GAM17979.1 - 0.013 15.1 0.0 14 5.2 0.0 4.0 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.12 GAM17979.1 - 0.018 14.6 2.1 21 4.5 0.0 4.5 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.13 GAM17979.1 - 0.047 13.3 0.1 9.7 5.7 0.0 3.3 3 0 0 3 3 3 0 Bacterial dnaA protein LpxK PF02606.9 GAM17979.1 - 0.051 12.5 0.3 0.56 9.0 0.0 2.5 3 0 0 3 3 2 0 Tetraacyldisaccharide-1-P 4'-kinase PhoH PF02562.11 GAM17979.1 - 0.064 12.4 0.1 5.5 6.1 0.0 3.7 5 0 0 5 5 4 0 PhoH-like protein AAA_5 PF07728.9 GAM17980.1 - 6.1e-07 29.2 0.0 2.9e-06 27.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NnrU PF07298.6 GAM17983.1 - 0.28 10.5 8.5 0.076 12.3 3.6 1.7 2 0 0 2 2 2 0 NnrU protein Folliculin PF11704.3 GAM17984.1 - 0.00063 19.3 0.1 0.00063 19.3 0.1 2.8 3 0 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport zf-RING_2 PF13639.1 GAM17985.1 - 0.00079 19.1 1.0 0.0014 18.3 0.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM17985.1 - 0.0013 18.8 0.8 0.0022 18.0 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAM17985.1 - 0.0032 17.0 0.5 0.0052 16.4 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM17985.1 - 0.041 13.5 2.2 0.084 12.5 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM17985.1 - 0.062 13.3 1.5 0.11 12.5 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PBP1_TM PF14812.1 GAM17985.1 - 0.46 10.8 13.3 0.74 10.1 9.0 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2046 PF09755.4 GAM17986.1 - 3.5e-22 78.7 37.0 6.2e-21 74.5 18.3 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) MetW PF07021.7 GAM17986.1 - 0.074 12.4 2.6 0.18 11.1 1.4 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW RRF_GI PF12614.3 GAM17986.1 - 0.63 9.8 15.8 0.041 13.6 2.5 2.7 1 1 0 2 2 2 0 Ribosome recycling factor DUF1788 PF08747.6 GAM17986.1 - 5.6 6.8 12.3 0.29 10.9 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) Methyltransf_11 PF08241.7 GAM17987.1 - 2.3e-16 60.0 0.0 4.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM17987.1 - 2.2e-09 37.2 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM17987.1 - 2.6e-09 37.4 0.0 5.8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM17987.1 - 1.1e-06 28.2 0.3 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM17987.1 - 2.2e-06 26.9 0.0 1.5e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM17987.1 - 8.9e-05 22.7 0.0 0.00031 21.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAM17987.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 GAM17987.1 - 0.0023 18.4 1.0 0.28 11.7 0.7 2.4 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAM17987.1 - 0.022 14.1 0.0 0.06 12.7 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 GAM17987.1 - 0.055 13.5 0.1 0.19 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 GAM17987.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.9 GAM17987.1 - 0.18 11.1 0.3 1.5 8.1 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase small domain FNIP PF05725.7 GAM17989.1 - 2.4e-83 273.8 25.5 3.3e-11 42.9 0.0 12.1 9 1 4 13 13 13 12 FNIP Repeat DUF1769 PF08588.5 GAM17989.1 - 0.0014 18.5 18.2 3 7.8 0.0 8.9 5 4 7 12 12 12 2 Protein of unknown function (DUF1769) GyrI-like PF06445.10 GAM17990.1 - 2.7e-27 95.7 0.0 3e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.1 GAM17990.1 - 0.0064 16.5 0.0 0.01 15.8 0.0 1.4 1 1 0 1 1 1 1 Integron-associated effector binding protein SOUL PF04832.7 GAM17990.1 - 0.053 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 SOUL heme-binding protein E1-E2_ATPase PF00122.15 GAM17992.1 - 7.9e-46 155.9 2.1 7.9e-46 155.9 1.5 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAM17992.1 - 4.7e-19 69.6 0.0 2.5e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM17992.1 - 2.4e-17 63.7 0.4 7.4e-17 62.1 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM17992.1 - 3.6e-15 55.1 0.0 9.9e-15 53.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAM17992.1 - 1.8e-08 34.1 0.0 4.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM17992.1 - 0.0038 16.8 0.8 0.043 13.3 0.1 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.27 GAM17993.1 - 3.4e-13 47.8 0.0 0.00053 19.1 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 GAM17993.1 - 1.2e-11 43.3 0.0 0.00041 19.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 GAM17993.1 - 2.1e-11 43.7 0.0 4.6e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM17993.1 - 4.8e-11 41.5 0.0 0.0004 20.0 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM17993.1 - 1.4e-06 27.8 0.0 0.00027 20.4 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair Secretin_N PF03958.12 GAM17993.1 - 0.081 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Aa_trans PF01490.13 GAM17994.1 - 3.1e-54 184.0 29.4 3.6e-54 183.8 20.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Acetyltransf_7 PF13508.1 GAM17997.1 - 4.2e-14 52.4 1.9 0.0033 17.5 0.0 4.8 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM17997.1 - 1.3e-11 44.3 0.0 0.054 13.5 0.0 4.6 4 0 0 4 4 4 4 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 GAM17997.1 - 1.3e-07 31.3 0.0 0.99 9.3 0.0 4.7 5 0 0 5 5 5 3 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 GAM17997.1 - 0.00026 21.0 0.0 18 5.4 0.0 4.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM17997.1 - 0.0048 16.6 1.5 16 5.3 0.0 4.8 6 0 0 6 6 6 2 FR47-like protein Pkinase PF00069.20 GAM17998.1 - 1.2e-69 234.3 0.0 1.4e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM17998.1 - 4.2e-32 111.2 0.0 7.5e-32 110.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM17998.1 - 1.9e-05 23.8 0.1 0.03 13.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 GAM17998.1 - 0.00031 20.1 1.4 0.00069 19.0 1.0 1.4 1 1 0 1 1 1 1 RIO1 family RhoGAP PF00620.22 GAM17999.1 - 2.1e-32 111.8 0.3 4.2e-32 110.8 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain Choline_kinase PF01633.15 GAM18000.1 - 5.5e-64 215.6 0.0 9.2e-64 214.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 GAM18000.1 - 1.1e-11 44.9 0.0 2.1e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAM18000.1 - 0.00015 21.0 0.4 0.0013 17.9 0.1 2.3 2 1 1 3 3 3 2 Ecdysteroid kinase Kdo PF06293.9 GAM18000.1 - 0.042 12.8 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spc42p PF11544.3 GAM18001.1 - 0.017 15.0 1.3 0.03 14.2 0.9 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p zf-C3HC4_3 PF13920.1 GAM18002.1 - 1e-07 31.5 8.7 1.7e-07 30.7 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM18002.1 - 2.3e-06 27.5 10.5 4.1e-06 26.7 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM18002.1 - 4.2e-06 26.3 10.4 8.7e-06 25.2 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM18002.1 - 1.5e-05 24.7 7.8 2.7e-05 23.9 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM18002.1 - 0.00014 21.5 10.7 0.00029 20.5 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF4201 PF13870.1 GAM18002.1 - 0.00065 19.1 21.0 0.00065 19.1 14.5 7.3 3 2 3 7 7 7 1 Domain of unknown function (DUF4201) zf-RING_UBOX PF13445.1 GAM18002.1 - 0.0014 18.2 5.2 0.0049 16.5 3.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAM18002.1 - 0.0022 17.7 3.2 0.0046 16.6 2.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein APG6 PF04111.7 GAM18002.1 - 0.0023 17.0 9.1 0.0023 17.0 6.3 6.4 2 1 5 7 7 5 1 Autophagy protein Apg6 zf-rbx1 PF12678.2 GAM18002.1 - 0.0052 16.8 2.2 0.013 15.5 1.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 GAM18002.1 - 0.02 14.4 9.8 0.042 13.4 6.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 GAM18002.1 - 0.035 13.9 2.3 0.072 12.9 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 GAM18002.1 - 0.11 12.4 8.2 0.23 11.3 5.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_MLP1_2 PF07926.7 GAM18002.1 - 0.37 10.5 102.3 1.9 8.2 14.7 6.7 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Prok-RING_4 PF14447.1 GAM18002.1 - 0.55 9.8 7.0 1.7 8.2 4.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 SSP160 PF06933.6 GAM18002.1 - 0.61 8.0 13.5 0.91 7.4 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 GAM18002.1 - 0.67 9.7 19.7 1.6 8.5 13.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 GAM18002.1 - 0.69 9.6 14.3 2 8.1 9.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-Nse PF11789.3 GAM18002.1 - 1.4 8.4 5.7 3.5 7.2 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase PF00069.20 GAM18003.1 - 4e-52 176.9 3.3 4.9e-52 176.6 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18003.1 - 7.7e-21 74.3 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM18003.1 - 0.041 13.6 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_UL52 PF03121.10 GAM18005.1 - 4.8e-13 48.6 0.0 1.2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase CUE PF02845.11 GAM18006.1 - 6.4e-05 22.3 0.2 0.00018 20.9 0.1 1.8 1 0 0 1 1 1 1 CUE domain fn3_3 PF14686.1 GAM18006.1 - 0.019 15.0 4.2 0.47 10.6 0.0 3.5 2 1 1 3 3 3 0 Polysaccharide lyase family 4, domain II Myosin_head PF00063.16 GAM18007.1 - 8.5e-153 509.9 18.6 8.5e-153 509.9 12.9 2.3 3 0 0 3 3 3 1 Myosin head (motor domain) MyTH4 PF00784.12 GAM18007.1 - 4.6e-50 168.3 0.1 4.6e-27 94.2 0.0 3.6 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.13 GAM18007.1 - 2.8e-21 75.9 5.8 6e-10 39.3 0.0 4.0 3 0 0 3 3 3 2 FERM central domain SH3_2 PF07653.12 GAM18007.1 - 5.3e-12 45.0 0.0 2.8e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAM18007.1 - 1.3e-09 37.4 0.1 2.9e-08 33.1 0.0 2.7 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 GAM18007.1 - 1e-08 34.0 10.3 0.00075 18.9 0.2 4.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif RA PF00788.18 GAM18007.1 - 2.2e-07 31.2 0.0 4.4e-05 23.8 0.0 2.9 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 GAM18007.1 - 1.4e-06 27.5 0.0 3.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain FERM_N PF09379.5 GAM18007.1 - 0.0056 16.6 0.3 2.3 8.3 0.0 2.8 2 0 0 2 2 2 1 FERM N-terminal domain Dehalogenase PF13486.1 GAM18008.1 - 0.018 14.5 0.1 0.018 14.5 0.0 2.1 2 1 0 2 2 2 0 Reductive dehalogenase subunit CPL PF08144.6 GAM18008.1 - 0.12 12.2 1.3 4.3 7.1 0.0 2.5 1 1 1 2 2 2 0 CPL (NUC119) domain Voldacs PF03517.8 GAM18009.1 - 6.3e-17 61.6 28.2 5.3e-15 55.4 19.6 3.0 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.3 GAM18009.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 KH_1 PF00013.24 GAM18010.1 - 0.013 15.1 0.1 0.035 13.7 0.0 1.8 1 0 0 1 1 1 0 KH domain DUF3989 PF13150.1 GAM18011.1 - 0.16 11.4 0.2 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) EGF_2 PF07974.8 GAM18012.1 - 2.7e-05 24.2 28.8 0.013 15.6 6.9 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 GAM18012.1 - 0.00065 19.6 16.5 0.029 14.4 4.6 2.9 2 0 0 2 2 2 2 Human growth factor-like EGF EGF PF00008.22 GAM18012.1 - 0.0014 18.5 30.5 0.0085 16.0 5.3 2.9 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.22 GAM18013.1 - 0.00082 19.2 25.3 0.083 12.8 6.0 2.7 2 0 0 2 2 2 2 EGF-like domain SsgA PF04686.7 GAM18013.1 - 0.051 13.2 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Streptomyces sporulation and cell division protein, SsgA cEGF PF12662.2 GAM18013.1 - 2.2 8.0 14.0 0.78 9.4 0.7 2.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like Ribosomal_S17e PF00833.13 GAM18014.1 - 0.032 13.9 0.9 0.08 12.7 0.6 1.7 1 0 0 1 1 1 0 Ribosomal S17 DUF1955 PF09205.5 GAM18014.1 - 0.062 12.8 1.7 0.11 12.0 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) His_Phos_1 PF00300.17 GAM18015.1 - 1.2e-32 113.1 0.7 2.3e-32 112.2 0.5 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UCH PF00443.24 GAM18016.1 - 7.5e-42 143.2 0.3 1.2e-41 142.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAM18016.1 - 2.3e-13 50.0 4.1 5.2e-13 48.9 2.8 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 GAM18016.1 - 0.00029 20.3 0.1 0.00064 19.2 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 GAM18017.1 - 1.3e-08 34.2 0.7 4.7e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Mt_ATP-synt_B PF05405.9 GAM18017.1 - 0.0051 16.2 2.7 0.0051 16.2 1.9 2.3 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2951 PF11166.3 GAM18017.1 - 0.11 12.3 13.5 0.059 13.2 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) UPF0449 PF15136.1 GAM18017.1 - 0.56 10.4 9.6 0.23 11.7 1.4 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF605 PF04652.11 GAM18017.1 - 0.67 9.2 14.3 0.98 8.7 9.9 1.2 1 0 0 1 1 1 0 Vta1 like RGS PF00615.14 GAM18018.1 - 9.7e-24 83.7 0.9 1.8e-22 79.6 0.6 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain Med3 PF11593.3 GAM18018.1 - 0.025 13.8 12.6 0.03 13.5 8.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ORC6 PF05460.8 GAM18018.1 - 0.029 13.4 5.2 0.033 13.2 3.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Dicty_REP PF05086.7 GAM18018.1 - 0.18 9.4 10.1 0.24 9.1 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF605 PF04652.11 GAM18018.1 - 0.38 10.0 11.5 0.45 9.8 8.0 1.1 1 0 0 1 1 1 0 Vta1 like Ndc1_Nup PF09531.5 GAM18018.1 - 0.47 8.8 4.7 0.54 8.6 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAF-1_p150 PF11600.3 GAM18018.1 - 0.59 9.4 12.3 0.86 8.9 8.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pap_E4 PF02711.9 GAM18018.1 - 1.2 10.0 10.4 2.5 8.9 7.2 1.5 1 0 0 1 1 1 0 E4 protein DUF3439 PF11921.3 GAM18018.1 - 4 7.2 14.0 6.8 6.4 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Herpes_DNAp_acc PF04929.7 GAM18018.1 - 6 5.7 9.9 9.3 5.0 6.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Kelch_4 PF13418.1 GAM18019.1 - 1.5e-47 159.1 21.8 6.6e-09 35.4 0.0 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM18019.1 - 1.1e-36 124.1 20.7 6.1e-08 32.6 0.1 7.1 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM18019.1 - 6e-24 83.5 13.5 2.3e-06 27.4 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM18019.1 - 2.9e-22 77.8 13.4 1.2e-05 25.2 0.1 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 GAM18019.1 - 1.1e-18 66.4 16.2 0.00038 19.9 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAM18019.1 - 1.2e-15 56.5 16.2 1.5e-05 24.5 0.2 6.4 6 1 0 6 6 6 5 Kelch motif zf-C3HC4_3 PF13920.1 GAM18019.1 - 5.1e-13 48.4 11.5 1.2e-12 47.2 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.12 GAM18019.1 - 0.00025 20.7 3.6 0.00025 20.7 2.5 4.3 3 1 1 4 4 4 1 K-box region zf-C3HC4_2 PF13923.1 GAM18019.1 - 0.0066 16.4 14.8 0.016 15.2 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.4 GAM18019.1 - 0.074 13.0 3.2 0.24 11.4 2.2 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Beach PF02138.13 GAM18020.1 - 1.6e-111 372.1 0.1 3e-111 371.1 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM18020.1 - 5.1e-29 100.2 0.1 2.4e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 GAM18020.1 - 4.4e-19 67.5 7.3 7.9e-09 35.0 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Laminin_G_3 PF13385.1 GAM18020.1 - 3.2e-16 59.9 0.0 1.3e-15 57.9 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1088 PF06469.6 GAM18020.1 - 0.0026 17.2 0.9 0.0076 15.6 0.6 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Peptidase_M8 PF01457.11 GAM18021.1 - 2.6e-43 148.1 0.2 4e-43 147.5 0.1 1.2 1 0 0 1 1 1 1 Leishmanolysin Ank_4 PF13637.1 GAM18022.1 - 5.9e-30 103.0 5.3 2.5e-07 30.9 0.1 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM18022.1 - 2.3e-29 101.5 11.7 1.8e-13 50.5 1.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM18022.1 - 1.2e-28 97.4 5.4 3.1e-05 23.5 0.0 7.4 6 1 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 GAM18022.1 - 1.8e-16 58.5 11.6 0.014 15.5 0.1 8.1 6 2 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 GAM18022.1 - 4.8e-11 42.5 6.1 0.00034 20.7 0.1 5.7 4 2 2 6 6 6 5 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM18022.1 - 8.5e-08 31.8 4.0 2e-07 30.5 2.8 1.7 1 0 0 1 1 1 1 F-box-like SH2 PF00017.19 GAM18022.1 - 1.9e-07 30.7 0.0 6.8e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 SH2 domain F-box PF00646.28 GAM18022.1 - 3.4e-06 26.5 3.7 9.4e-06 25.1 2.6 1.8 1 0 0 1 1 1 1 F-box domain SH2_2 PF14633.1 GAM18022.1 - 0.0025 16.9 0.1 0.0089 15.1 0.0 1.9 2 0 0 2 2 2 1 SH2 domain GHMP_kinases_N PF00288.21 GAM18023.1 - 1.3e-19 69.9 0.1 4.3e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM18023.1 - 5.3e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PLDc PF00614.17 GAM18024.1 - 1.9e-19 68.7 8.0 4.4e-10 39.0 0.3 3.2 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 GAM18024.1 - 2e-13 50.1 0.9 7.3e-08 32.2 0.2 2.7 2 0 0 2 2 2 2 PLD-like domain Nsp3_PL2pro PF12124.3 GAM18024.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain CBM49 PF09478.5 GAM18025.1 - 3.2e-17 62.4 0.0 4.4e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Taxilin PF09728.4 GAM18027.1 - 0.0015 17.7 7.4 0.0021 17.2 5.2 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF1027 PF06265.6 GAM18027.1 - 0.018 14.9 0.4 0.036 13.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) ERM PF00769.14 GAM18027.1 - 0.97 8.9 15.8 0.33 10.4 8.6 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DivIC PF04977.10 GAM18027.1 - 1.9 8.0 7.8 18 4.9 0.0 3.2 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.1 GAM18027.1 - 3.5 6.7 16.1 1.5 8.0 8.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 GAM18027.1 - 4.3 5.5 30.5 0.022 13.0 11.2 2.3 1 1 0 2 2 2 0 Transmembrane protein Nup54 PF13874.1 GAM18027.1 - 4.7 6.8 8.4 23 4.6 0.0 3.0 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 Phospholip_B PF04916.8 GAM18028.1 - 2.7e-127 425.1 2.4 3.3e-127 424.9 1.7 1.0 1 0 0 1 1 1 1 Phospholipase B FNIP PF05725.7 GAM18029.1 - 6.9e-67 221.1 16.6 1.6e-13 50.3 0.0 9.2 6 2 3 10 10 10 8 FNIP Repeat F-box PF00646.28 GAM18029.1 - 0.017 14.7 0.8 0.056 13.1 0.5 1.9 1 0 0 1 1 1 0 F-box domain zf-RING_4 PF14570.1 GAM18030.1 - 3.4e-17 61.7 14.2 5.9e-17 60.9 9.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 GAM18030.1 - 2e-08 33.9 0.0 3.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM18030.1 - 7.5e-07 28.6 0.2 2.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 GAM18030.1 - 5.1e-06 26.0 9.0 9.4e-06 25.2 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 GAM18030.1 - 7.7e-05 22.0 1.8 7.7e-05 22.0 1.3 6.7 6 1 1 7 7 7 1 Rtf2 RING-finger RRM_6 PF14259.1 GAM18030.1 - 0.00028 20.8 0.0 0.00085 19.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 GAM18030.1 - 0.00065 19.4 9.5 0.0014 18.4 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM18030.1 - 0.0071 16.3 11.5 0.013 15.5 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM18030.1 - 0.098 12.3 11.1 0.22 11.2 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM18030.1 - 0.12 12.1 10.5 0.24 11.1 7.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF1375 PF07119.7 GAM18032.1 - 0.072 12.9 0.4 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) Consortin_C PF15281.1 GAM18032.1 - 0.22 11.0 1.2 0.4 10.1 0.9 1.3 1 0 0 1 1 1 0 Consortin C-terminus DUF900 PF05990.7 GAM18033.1 - 3.2e-24 85.5 0.0 4.9e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 GAM18033.1 - 0.0027 17.4 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM18033.1 - 0.0061 16.4 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Bunya_G1 PF03557.10 GAM18034.1 - 0.009 13.8 0.2 0.011 13.6 0.1 1.1 1 0 0 1 1 1 1 Bunyavirus glycoprotein G1 Sulfotransfer_2 PF03567.9 GAM18035.1 - 4.6e-12 46.1 6.7 7.3e-12 45.5 0.2 2.5 2 1 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM18035.1 - 1.6e-05 23.7 1.4 0.00019 20.2 0.2 2.4 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase KapB PF08810.5 GAM18035.1 - 0.0087 16.0 0.9 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 Kinase associated protein B ATP-synt_8 PF00895.15 GAM18035.1 - 0.01 16.0 4.2 0.028 14.6 2.9 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 NUC194 PF08163.7 GAM18035.1 - 0.029 13.2 1.2 0.042 12.6 0.9 1.2 1 0 0 1 1 1 0 NUC194 domain Sulfotransfer_3 PF13469.1 GAM18035.1 - 0.04 14.8 0.3 0.11 13.3 0.2 1.8 1 1 0 1 1 1 0 Sulfotransferase family Rad51 PF08423.6 GAM18036.1 - 1.8e-138 459.5 0.0 2.3e-138 459.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAM18036.1 - 3.1e-15 56.0 0.0 5.4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 GAM18036.1 - 3.5e-09 36.7 0.8 9.5e-09 35.3 0.6 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 GAM18036.1 - 4e-09 35.9 0.1 7.2e-09 35.1 0.0 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 GAM18036.1 - 5.3e-06 25.7 0.5 2.2e-05 23.7 0.3 2.0 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 GAM18036.1 - 0.036 14.1 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.6 GAM18036.1 - 0.099 11.4 0.0 0.98 8.1 0.0 2.1 2 0 0 2 2 2 0 PAXNEB protein MtaB PF12176.3 GAM18037.1 - 0.078 11.3 0.0 0.18 10.1 0.0 1.5 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit ArfGap PF01412.13 GAM18038.1 - 1.3e-37 128.0 0.2 1.3e-37 128.0 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PAT1 PF09770.4 GAM18038.1 - 0.14 10.3 19.9 0.17 10.0 13.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LRR_4 PF12799.2 GAM18039.1 - 1.5e-29 101.0 39.5 1.5e-09 37.2 2.0 5.7 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18039.1 - 7.6e-27 92.8 56.5 1.2e-09 37.7 3.0 4.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 GAM18039.1 - 1.2e-20 70.3 22.9 0.0022 17.7 0.1 8.6 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 GAM18039.1 - 3.7e-12 44.3 30.5 0.14 12.4 0.1 8.4 9 0 0 9 9 9 6 Leucine rich repeat LRR_6 PF13516.1 GAM18039.1 - 5.2e-07 29.0 29.5 1.1 9.4 0.1 8.2 8 0 0 8 8 8 4 Leucine Rich repeat DUF2322 PF10084.4 GAM18039.1 - 0.0017 18.0 0.1 0.22 11.2 0.0 2.9 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2322) Kelch_4 PF13418.1 GAM18039.1 - 0.056 13.2 0.0 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain ORMDL PF04061.9 GAM18040.1 - 2.5e-40 137.2 2.3 2.8e-40 137.0 1.6 1.0 1 0 0 1 1 1 1 ORMDL family BSD PF03909.12 GAM18040.1 - 0.17 11.6 0.5 0.83 9.4 0.0 2.1 2 0 0 2 2 2 0 BSD domain DER1 PF04511.10 GAM18041.1 - 2.1e-47 161.2 9.8 2.4e-47 161.0 6.8 1.0 1 0 0 1 1 1 1 Der1-like family ABC2_membrane PF01061.19 GAM18042.1 - 8.7e-38 129.5 25.2 8.7e-38 129.5 17.5 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 GAM18042.1 - 1.5e-24 86.8 0.0 2.4e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM18042.1 - 1.1e-11 45.2 1.5 6.1e-07 29.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAM18042.1 - 8.3e-05 21.8 1.7 0.093 11.7 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM18042.1 - 0.001 18.3 0.0 0.11 11.6 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 GAM18042.1 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 GAM18042.1 - 0.017 14.5 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAM18042.1 - 0.018 14.2 0.1 0.035 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM18042.1 - 0.05 13.1 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain hEGF PF12661.2 GAM18042.1 - 0.11 12.6 3.0 0.46 10.6 2.1 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF AAA_16 PF13191.1 GAM18042.1 - 0.17 11.8 0.1 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain NADH-G_4Fe-4S_3 PF10588.4 GAM18042.1 - 1.6 8.0 5.5 6.9 5.9 0.0 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region ABC2_membrane_2 PF12679.2 GAM18042.1 - 3.6 6.3 13.9 0.26 10.0 5.9 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein NDK PF00334.14 GAM18043.1 - 1.8e-55 186.4 0.0 2.1e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF3414 PF11894.3 GAM18044.1 - 3.8e-71 239.6 45.1 6.4e-65 219.0 22.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3414) Pico_P1A PF02226.11 GAM18044.1 - 0.017 14.8 0.3 0.099 12.3 0.0 2.4 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) FNIP PF05725.7 GAM18045.1 - 2.4e-82 270.6 42.1 1.8e-14 53.3 0.7 11.1 5 3 2 11 11 11 10 FNIP Repeat DUF1769 PF08588.5 GAM18045.1 - 3.5e-05 23.6 3.1 2.8 7.9 0.0 6.0 4 2 3 7 7 7 3 Protein of unknown function (DUF1769) Myotub-related PF06602.9 GAM18046.1 - 2e-114 382.0 0.0 3.9e-114 381.1 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAM18046.1 - 0.0034 17.6 2.5 0.0092 16.2 0.0 2.7 3 0 0 3 3 3 1 Tyrosine phosphatase family Resolvase PF00239.16 GAM18047.1 - 5.6e-10 39.2 0.0 4.8e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Resolvase, N terminal domain PapG_C PF03628.8 GAM18048.1 - 0.086 12.5 0.6 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 PapG chaperone-binding domain Cyclin_N PF00134.18 GAM18049.1 - 1.7e-16 59.9 3.7 3e-16 59.1 2.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM18049.1 - 5.6e-06 26.2 0.2 0.15 11.9 0.2 2.8 2 1 0 2 2 2 2 Cyclin, C-terminal domain PRP38 PF03371.10 GAM18049.1 - 0.033 13.8 1.1 0.13 11.8 0.1 2.1 1 1 1 2 2 2 0 PRP38 family ATP-synt_C PF00137.16 GAM18050.1 - 1.1e-24 86.1 36.0 9.4e-14 51.0 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Response_reg PF00072.19 GAM18051.1 - 8.7e-27 93.3 2.8 3.9e-20 71.9 0.0 3.4 3 1 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.21 GAM18051.1 - 1.1e-25 89.4 0.7 3e-25 88.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM18051.1 - 6.7e-16 58.0 0.4 1.4e-15 57.0 0.3 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 GAM18051.1 - 0.023 14.4 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Costars PF14705.1 GAM18052.1 - 6.1e-31 106.2 0.4 6.8e-31 106.0 0.3 1.0 1 0 0 1 1 1 1 Costars ArfGap PF01412.13 GAM18053.1 - 2.7e-28 98.0 0.3 2.7e-28 98.0 0.2 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-TRAF PF02176.13 GAM18053.1 - 0.017 15.4 9.1 0.065 13.6 3.3 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger TF_Zn_Ribbon PF08271.7 GAM18053.1 - 1.3 8.3 8.4 0.62 9.4 1.3 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding CPSF73-100_C PF11718.3 GAM18053.1 - 1.4 8.2 3.9 0.67 9.2 0.2 2.1 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Pkinase PF00069.20 GAM18054.1 - 6.4e-72 241.8 0.0 1e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18054.1 - 4.7e-45 153.6 0.0 7.3e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 GAM18054.1 - 3.5e-40 134.4 31.1 1e-07 31.5 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat PB1 PF00564.19 GAM18054.1 - 1.5e-12 47.0 0.0 2.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain F-box-like PF12937.2 GAM18054.1 - 4.6e-10 39.0 0.5 8.5e-10 38.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM18054.1 - 2.9e-09 36.3 0.9 5.6e-09 35.4 0.6 1.5 1 0 0 1 1 1 1 F-box domain Kinase-like PF14531.1 GAM18054.1 - 3.8e-07 29.3 0.4 9.2e-07 28.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Nup160 PF11715.3 GAM18054.1 - 1.6e-05 23.2 16.0 3.5 5.6 0.1 6.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 APH PF01636.18 GAM18054.1 - 0.22 11.2 0.0 0.73 9.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.2 GAM18055.1 - 3.1e-35 120.3 4.5 1.8e-21 76.3 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM18055.1 - 1.4e-26 90.8 7.1 2.4e-10 39.7 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAM18055.1 - 2.9e-22 78.6 12.3 7.3e-09 35.9 0.3 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM18055.1 - 1.6e-20 72.6 7.2 7.9e-10 38.6 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18055.1 - 1.5e-16 58.8 3.0 3.1e-06 26.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat SAP PF02037.22 GAM18058.1 - 2e-10 39.8 2.4 4.2e-10 38.8 1.7 1.6 1 0 0 1 1 1 1 SAP domain BUD22 PF09073.5 GAM18058.1 - 0.0042 16.2 23.9 0.0067 15.5 16.6 1.3 1 0 0 1 1 1 1 BUD22 SAPS PF04499.10 GAM18058.1 - 0.011 14.3 5.0 0.011 14.4 3.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 GAM18058.1 - 0.038 12.4 27.0 0.055 11.9 18.7 1.2 1 0 0 1 1 1 0 Daxx Family HeH PF12949.2 GAM18058.1 - 0.058 12.9 2.5 0.064 12.8 0.3 2.2 2 1 0 2 2 2 0 HeH/LEM domain Merozoite_SPAM PF07133.6 GAM18058.1 - 0.065 13.1 29.8 0.13 12.1 20.7 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RRN3 PF05327.6 GAM18058.1 - 0.097 10.7 7.7 0.16 10.0 5.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 GAM18058.1 - 0.11 10.5 12.1 0.13 10.2 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 GAM18058.1 - 0.11 11.6 15.5 0.16 11.1 10.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Paf1 PF03985.8 GAM18058.1 - 0.14 10.8 29.3 0.22 10.2 20.3 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 GAM18058.1 - 0.19 9.5 24.9 0.3 8.9 17.2 1.3 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 GAM18058.1 - 0.31 10.2 33.4 0.46 9.6 23.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 GAM18058.1 - 0.32 9.4 32.4 0.44 8.9 22.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 GAM18058.1 - 0.39 10.4 19.1 0.67 9.7 13.2 1.3 1 0 0 1 1 1 0 DDHD domain Trypan_PARP PF05887.6 GAM18058.1 - 0.67 9.7 29.3 1.1 9.0 20.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pilt PF15453.1 GAM18058.1 - 0.7 9.5 19.1 1.1 8.9 13.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions F-protein PF00469.15 GAM18058.1 - 0.85 8.9 9.0 1.8 7.8 6.2 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SprA-related PF12118.3 GAM18058.1 - 2.3 7.4 25.7 3.5 6.8 17.8 1.2 1 0 0 1 1 1 0 SprA-related family Mucin PF01456.12 GAM18058.1 - 9.1 6.0 18.0 16 5.2 12.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Drc1-Sld2 PF11719.3 GAM18058.1 - 9.5 5.1 30.5 17 4.3 21.2 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Asp-B-Hydro_N PF05279.6 GAM18058.1 - 9.7 5.9 35.3 15 5.3 24.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SdiA-regulated PF06977.6 GAM18060.1 - 0.00071 18.6 0.0 0.0016 17.4 0.0 1.5 1 1 0 1 1 1 1 SdiA-regulated PEX11 PF05648.9 GAM18062.1 - 5.8e-55 185.9 2.8 6.7e-55 185.7 1.9 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) ABC2_membrane PF01061.19 GAM18063.1 - 0.02 14.0 1.4 0.036 13.2 1.0 1.3 1 0 0 1 1 1 0 ABC-2 type transporter ABC2_membrane_4 PF12730.2 GAM18063.1 - 0.029 13.5 4.6 0.04 13.0 3.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RE_CfrBI PF09516.5 GAM18063.1 - 0.051 12.4 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease Claudin_2 PF13903.1 GAM18063.1 - 0.061 13.0 0.3 0.077 12.6 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 GAM18063.1 - 0.51 9.5 4.9 0.77 8.9 3.4 1.2 1 0 0 1 1 1 0 Tetraspanin family Peptidase_S28 PF05577.7 GAM18064.1 - 8.3e-125 416.7 8.2 9.5e-125 416.5 5.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 GAM18064.1 - 9.7e-05 20.9 0.1 0.00023 19.7 0.1 1.5 2 0 0 2 2 2 1 PS-10 peptidase S37 NAD_binding_10 PF13460.1 GAM18065.1 - 4.1e-09 36.7 0.0 5.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM18065.1 - 1e-08 34.9 0.9 0.00078 18.9 0.1 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM18065.1 - 3.1e-06 26.6 0.0 6.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM18065.1 - 1.3e-05 24.0 0.9 0.01 14.5 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.22 GAM18065.1 - 0.00025 21.3 0.1 0.0016 18.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 GAM18065.1 - 0.00088 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 GAM18065.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAM18065.1 - 0.002 17.0 0.3 0.27 10.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 GAM18065.1 - 0.0027 16.9 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 GAM18065.1 - 0.024 13.5 0.0 1.9 7.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.10 GAM18065.1 - 0.031 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 GAM18065.1 - 0.07 12.7 1.0 0.25 11.0 0.7 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ETF_alpha PF00766.14 GAM18066.1 - 5.2e-38 128.5 0.7 1.4e-37 127.1 0.5 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 GAM18066.1 - 2.9e-37 127.8 0.6 4.7e-37 127.2 0.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ras PF00071.17 GAM18067.1 - 1.9e-23 82.6 0.5 2.6e-23 82.1 0.3 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM18067.1 - 7.2e-14 52.3 0.1 1.3e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM18067.1 - 0.00039 19.7 1.8 0.0012 18.0 1.2 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 GAM18067.1 - 0.0044 16.2 0.0 0.011 14.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM18067.1 - 0.0068 16.3 0.1 0.016 15.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.8 GAM18067.1 - 0.015 14.2 0.0 0.039 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.11 GAM18067.1 - 0.019 14.1 0.2 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 AIG1 family AAA_29 PF13555.1 GAM18067.1 - 0.027 13.9 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 GAM18067.1 - 0.031 14.0 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM18067.1 - 0.039 14.0 0.1 0.057 13.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF4174 PF13778.1 GAM18067.1 - 0.062 13.4 0.1 3.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) AAA_16 PF13191.1 GAM18067.1 - 0.19 11.6 0.2 0.4 10.6 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain FNIP PF05725.7 GAM18068.1 - 2.1e-87 286.8 22.1 9.1e-13 47.9 1.9 12.8 6 2 5 14 14 14 13 FNIP Repeat EXS PF03124.9 GAM18068.1 - 0.049 12.6 1.5 0.077 12.0 1.0 1.2 1 0 0 1 1 1 0 EXS family Pas_Saposin PF09016.5 GAM18068.1 - 0.14 12.1 1.1 0.44 10.5 0.8 1.8 1 0 0 1 1 1 0 Pas factor saposin fold CAP_N PF01213.14 GAM18068.1 - 0.67 9.1 6.6 1.1 8.4 4.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RhoGAP PF00620.22 GAM18069.1 - 5.4e-31 107.2 5.2 1.4e-30 105.9 0.1 2.8 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.18 GAM18069.1 - 4.1e-08 33.3 3.1 7.5e-08 32.4 0.5 2.7 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PP28 PF10252.4 GAM18069.1 - 0.0043 17.0 3.0 0.01 15.8 2.1 1.6 1 0 0 1 1 1 1 Casein kinase substrate phosphoprotein PP28 ATP-synt_B PF00430.13 GAM18069.1 - 0.042 13.6 4.2 0.049 13.4 1.7 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1394 PF07159.7 GAM18070.1 - 2e-136 454.0 0.7 2.3e-136 453.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF2331 PF10093.4 GAM18070.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) PNRC PF15365.1 GAM18071.1 - 9.7e-15 54.3 0.3 9.7e-15 54.3 0.2 3.2 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator adh_short PF00106.20 GAM18072.1 - 2.1e-23 83.0 0.4 3e-23 82.5 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM18072.1 - 2.4e-10 40.3 0.1 3.7e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM18072.1 - 2.3e-09 37.3 0.2 3.3e-09 36.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM18072.1 - 4.5e-06 26.2 0.1 6.5e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 GAM18072.1 - 0.0025 16.9 0.0 0.0047 16.0 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 GAM18072.1 - 0.0039 16.1 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM18072.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 GAM18072.1 - 0.018 13.7 0.1 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM18072.1 - 0.047 13.6 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Snf7 PF03357.16 GAM18073.1 - 1.8e-34 118.5 11.3 2.4e-34 118.1 7.9 1.1 1 0 0 1 1 1 1 Snf7 TPR_MLP1_2 PF07926.7 GAM18073.1 - 0.39 10.4 10.6 0.088 12.5 3.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2681 PF10883.3 GAM18073.1 - 0.57 10.4 4.6 1.6 8.9 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) Toxin_52 PF15605.1 GAM18073.1 - 1.2 9.0 4.4 2.5 8.0 1.4 2.4 2 1 1 3 3 3 0 Putative toxin 52 FKBP_N PF01346.13 GAM18073.1 - 1.7 8.6 7.0 0.43 10.6 1.5 2.2 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase IncA PF04156.9 GAM18073.1 - 3.9 7.0 12.1 32 4.0 7.5 2.2 1 1 1 2 2 2 0 IncA protein DUF342 PF03961.8 GAM18073.1 - 5 5.4 8.2 2.5 6.4 4.1 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF342) MCC-bdg_PDZ PF10506.4 GAM18073.1 - 5.1 7.0 7.8 0.72 9.7 2.4 1.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Med28 PF11594.3 GAM18073.1 - 6.5 7.0 7.6 0.91 9.7 1.0 2.4 2 1 1 3 3 3 0 Mediator complex subunit 28 bZIP_1 PF00170.16 GAM18074.1 - 1e-06 28.5 15.7 4.5e-06 26.5 10.9 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM18074.1 - 0.00024 20.8 13.2 0.00024 20.8 9.1 2.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM18074.1 - 0.016 15.5 9.4 0.016 15.5 6.5 2.5 2 1 1 3 3 3 0 bZIP Maf transcription factor DMPK_coil PF08826.5 GAM18074.1 - 0.081 12.8 10.6 0.046 13.6 5.4 2.1 1 1 1 2 2 2 0 DMPK coiled coil domain like HPP PF04982.8 GAM18075.1 - 1.3e-40 137.9 8.4 1.9e-40 137.4 5.8 1.2 1 0 0 1 1 1 1 HPP family CBFD_NFYB_HMF PF00808.18 GAM18076.1 - 2.1e-18 66.1 0.6 3.2e-18 65.5 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM18076.1 - 2.2e-08 34.0 0.2 4.6e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_M24 PF00557.19 GAM18077.1 - 1e-52 178.7 0.0 1.6e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAM18077.1 - 2.7e-26 91.5 0.0 5.4e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.2 GAM18077.1 - 0.039 13.5 0.6 0.1 12.1 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3793) UCH PF00443.24 GAM18078.1 - 1.4e-48 165.3 1.0 2.7e-48 164.4 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM18078.1 - 7e-15 55.2 4.8 7e-15 55.2 3.4 1.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DBD_Tnp_Hermes PF10683.4 GAM18080.1 - 0.13 11.7 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Ribosomal_S27e PF01667.12 GAM18081.1 - 1.3e-23 82.2 2.9 1.6e-23 82.0 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Tmemb_55A PF09788.4 GAM18081.1 - 0.00039 19.6 0.5 0.00042 19.5 0.4 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A IBR PF01485.16 GAM18081.1 - 0.0073 16.1 0.5 0.011 15.6 0.4 1.2 1 0 0 1 1 1 1 IBR domain zinc_ribbon_6 PF14599.1 GAM18081.1 - 0.073 12.8 0.6 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon Cytochrom_CIII PF02085.11 GAM18081.1 - 0.089 12.8 0.5 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Class III cytochrome C family Yippee-Mis18 PF03226.9 GAM18081.1 - 0.11 12.5 3.0 1.2 9.1 0.1 2.1 1 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-LSD1 PF06943.7 GAM18081.1 - 4.5 6.9 5.9 5.6 6.6 0.1 2.5 2 1 1 3 3 3 0 LSD1 zinc finger EF-hand_1 PF00036.27 GAM18082.1 - 2.5e-15 54.4 0.9 7.5e-06 24.8 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 GAM18082.1 - 2.3e-14 53.2 0.2 4.7e-11 42.6 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM18082.1 - 1.7e-11 43.5 2.1 3.8e-09 36.0 0.2 3.6 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM18082.1 - 8.5e-11 40.8 0.2 0.00095 18.8 0.1 3.6 3 1 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.1 GAM18082.1 - 9.5e-06 25.4 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM18082.1 - 0.00082 18.6 4.3 0.67 9.3 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.1 GAM18082.1 - 0.0062 16.1 0.1 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 GAM18082.1 - 0.0091 15.7 0.2 0.022 14.5 0.1 1.7 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand PB1 PF00564.19 GAM18082.1 - 0.024 14.2 1.1 0.96 9.1 0.0 3.1 3 1 1 4 4 4 0 PB1 domain Robl_LC7 PF03259.12 GAM18083.1 - 3.8e-15 55.2 0.0 4.5e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain DUF1506 PF07405.6 GAM18083.1 - 0.0025 17.8 0.1 0.0029 17.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1506) LSM PF01423.17 GAM18084.1 - 2.7e-17 62.0 0.8 3.7e-17 61.6 0.6 1.2 1 0 0 1 1 1 1 LSM domain Leu_zip PF15294.1 GAM18084.1 - 0.0058 15.7 0.2 0.0066 15.5 0.2 1.0 1 0 0 1 1 1 1 Leucine zipper Pro_isomerase PF00160.16 GAM18085.1 - 1.1e-46 158.8 0.7 1.8e-46 158.1 0.5 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 GAM18085.1 - 3e-25 87.6 4.8 4.5e-13 48.6 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM18085.1 - 2.7e-18 64.7 6.5 6.6e-06 25.5 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM18085.1 - 7.4e-18 62.9 2.9 5.4e-05 22.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM18085.1 - 3.9e-09 36.9 3.0 0.00012 22.6 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM18085.1 - 2.5e-08 33.1 0.5 0.019 14.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM18085.1 - 2.9e-08 33.5 2.7 0.011 15.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM18085.1 - 8.4e-08 31.9 0.7 0.013 15.4 0.0 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 GAM18085.1 - 9.1e-06 25.9 0.5 0.16 12.3 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18085.1 - 2.3e-05 23.8 6.5 0.06 13.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM18085.1 - 2.6e-05 24.4 0.0 0.34 11.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM18085.1 - 4.7e-05 23.5 1.9 1 9.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM18085.1 - 6.8e-05 22.7 0.3 0.51 10.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAM18085.1 - 6.9e-05 22.6 0.3 0.13 12.2 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM18085.1 - 0.00066 19.7 3.4 0.012 15.7 1.3 2.3 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM18085.1 - 0.0011 18.8 0.0 0.0089 15.8 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 GAM18085.1 - 0.0054 15.9 1.4 0.011 14.8 1.0 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Glyco_trans_1_2 PF13524.1 GAM18085.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF3856 PF12968.2 GAM18085.1 - 0.028 14.2 0.3 0.061 13.1 0.1 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) DUF3808 PF10300.4 GAM18085.1 - 0.065 11.7 0.2 0.15 10.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_20 PF14561.1 GAM18085.1 - 0.1 12.7 0.5 0.32 11.1 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 GAM18085.1 - 0.12 12.2 1.6 3.5 7.5 0.3 3.1 2 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ras PF00071.17 GAM18086.1 - 7.3e-31 106.7 0.0 1.5e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM18086.1 - 1e-14 54.1 0.0 2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM18086.1 - 3.6e-13 50.0 0.0 2.2e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein LRR_6 PF13516.1 GAM18086.1 - 0.00042 20.0 37.3 0.0026 17.6 0.1 7.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 GAM18086.1 - 4.8 7.5 23.0 3.5 8.0 0.0 6.6 5 1 0 5 5 5 0 Leucine Rich Repeat zf-AN1 PF01428.11 GAM18087.1 - 9.6e-20 70.1 37.8 9.3e-11 41.4 9.8 3.0 3 0 0 3 3 3 2 AN1-like Zinc finger UBX PF00789.15 GAM18087.1 - 1.5e-07 31.3 0.0 3.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain Transp_Tc5_C PF04236.10 GAM18087.1 - 0.089 13.0 20.3 0.05 13.8 4.7 2.7 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-FPG_IleRS PF06827.9 GAM18087.1 - 0.51 10.0 5.5 5.1 6.8 1.4 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS IBR PF01485.16 GAM18087.1 - 6.9 6.6 28.7 22 5.0 10.2 3.3 1 1 1 2 2 2 0 IBR domain Pkinase PF00069.20 GAM18088.1 - 9e-61 205.2 0.2 2.3e-60 203.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18088.1 - 1.3e-60 204.6 0.0 2.2e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Filamin PF00630.14 GAM18088.1 - 6.8e-05 23.3 0.2 0.0002 21.8 0.0 2.0 2 0 0 2 2 2 1 Filamin/ABP280 repeat Kinase-like PF14531.1 GAM18088.1 - 0.0017 17.3 0.8 0.0033 16.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Ubiquitin_2 PF14560.1 GAM18088.1 - 0.0022 18.2 0.0 0.012 15.9 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin-like domain Arm PF00514.18 GAM18088.1 - 0.0049 16.6 0.4 19 5.2 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM18088.1 - 0.015 15.5 0.0 0.24 11.7 0.0 2.9 1 1 2 3 3 3 0 HEAT repeats APH PF01636.18 GAM18088.1 - 0.21 11.2 0.2 0.54 9.9 0.2 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 GAM18090.1 - 1.4e-82 277.7 5.0 1.7e-82 277.4 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.6 GAM18090.1 - 0.0046 16.0 0.1 1.5 7.7 0.0 3.1 3 0 0 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Cofilin_ADF PF00241.15 GAM18091.1 - 9.8e-17 61.0 0.2 1.1e-16 60.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pkinase PF00069.20 GAM18093.1 - 2.4e-69 233.3 0.1 2.4e-69 233.3 0.0 3.3 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18093.1 - 1.1e-32 113.1 0.0 1.1e-32 113.1 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Caldesmon PF02029.10 GAM18093.1 - 7e-05 21.4 0.5 7e-05 21.4 0.4 2.1 2 0 0 2 2 2 1 Caldesmon Spore_coat_CotO PF14153.1 GAM18093.1 - 0.0055 16.1 21.1 0.0055 16.1 14.6 2.4 2 1 0 2 2 2 1 Spore coat protein CotO SPX PF03105.14 GAM18093.1 - 0.015 15.0 27.0 0.026 14.3 7.6 2.2 2 0 0 2 2 2 0 SPX domain Neur_chan_memb PF02932.11 GAM18093.1 - 0.06 13.2 21.0 0.69 9.7 9.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pup PF05639.6 GAM18093.1 - 0.84 10.1 0.0 0.84 10.1 0.0 4.6 3 1 0 3 3 3 0 Pup-like protein Mem_trans PF03547.13 GAM18093.1 - 3.7 5.7 9.1 0.046 12.0 0.2 1.9 2 0 0 2 2 2 0 Membrane transport protein Ycf1 PF05758.7 GAM18093.1 - 4.3 4.9 30.7 0.13 9.9 9.8 2.1 2 0 0 2 2 2 0 Ycf1 Exonuc_VII_L PF02601.10 GAM18093.1 - 4.4 6.3 37.8 0.091 11.9 11.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3595 PF12166.3 GAM18094.1 - 1e-84 284.8 5.1 1e-84 284.8 3.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3595) DUF3484 PF11983.3 GAM18094.1 - 0.046 14.5 2.9 0.18 12.6 2.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) FNIP PF05725.7 GAM18095.1 - 8.8e-57 188.8 8.7 1.2e-11 44.3 1.0 7.8 5 2 1 8 8 8 7 FNIP Repeat SPX PF03105.14 GAM18096.1 - 4.9e-22 79.0 12.3 1.4e-10 41.3 0.3 3.1 1 1 1 2 2 2 2 SPX domain EF-hand_1 PF00036.27 GAM18096.1 - 0.0015 17.6 0.1 0.52 9.7 0.0 3.1 3 0 0 3 3 3 1 EF hand Nsp1_C PF05064.8 GAM18096.1 - 0.0043 16.6 0.5 0.014 15.0 0.3 1.9 1 1 0 1 1 1 1 Nsp1-like C-terminal region EF-hand_7 PF13499.1 GAM18096.1 - 0.026 14.6 0.7 0.57 10.3 0.5 2.4 1 1 0 1 1 1 0 EF-hand domain pair DUF1664 PF07889.7 GAM18096.1 - 0.044 13.5 0.2 0.074 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3907 PF13047.1 GAM18096.1 - 0.087 12.4 0.6 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) DUF2827 PF10933.3 GAM18096.1 - 0.088 11.2 0.3 0.13 10.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) DUF3461 PF11944.3 GAM18096.1 - 0.14 12.0 2.5 1.1 9.1 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3461) CAML PF14963.1 GAM18097.1 - 0.0023 17.3 1.4 0.0045 16.3 0.9 1.4 1 0 0 1 1 1 1 Calcium signal-modulating cyclophilin ligand DUF966 PF06136.8 GAM18097.1 - 0.0035 16.8 5.7 0.0034 16.8 3.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF966) Presenilin PF01080.12 GAM18097.1 - 0.086 11.6 8.0 0.15 10.8 5.5 1.5 1 0 0 1 1 1 0 Presenilin Rifin_STEVOR PF02009.11 GAM18097.1 - 0.14 11.7 10.1 0.054 13.1 3.4 2.2 1 1 1 2 2 2 0 Rifin/stevor family TFIIA PF03153.8 GAM18097.1 - 0.78 9.5 11.0 1.2 8.9 7.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 GAM18097.1 - 0.86 8.1 23.1 1 7.9 16.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 GAM18097.1 - 4.2 5.5 16.3 4.9 5.3 11.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Mitofilin PF09731.4 GAM18097.1 - 6 5.3 11.4 8.2 4.9 7.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DNA_pol_viral_N PF00242.12 GAM18097.1 - 9.5 5.1 16.2 13 4.6 11.2 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RPN7 PF10602.4 GAM18098.1 - 1.5e-54 184.0 0.8 2.4e-54 183.3 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 GAM18098.1 - 6.8e-18 64.9 0.1 3.7e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 PCI domain SDH_alpha PF03313.10 GAM18099.1 - 0.0085 15.1 2.7 0.0093 15.0 1.9 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain Coiled PF05710.7 GAM18099.1 - 0.012 16.0 17.1 0.029 14.8 11.9 1.6 1 1 0 1 1 1 0 Coiled coil DUF1084 PF06454.6 GAM18100.1 - 2e-14 53.2 21.5 1.1e-13 50.8 14.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF3397 PF11877.3 GAM18100.1 - 0.011 15.7 6.1 0.011 15.7 4.2 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3397) TIG PF01833.19 GAM18102.1 - 2.7e-09 36.8 47.7 2.7e-07 30.4 2.7 7.1 4 2 3 7 7 7 4 IPT/TIG domain PHD PF00628.24 GAM18103.1 - 1e-06 28.3 18.2 0.00015 21.3 2.5 3.5 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 GAM18103.1 - 3.8e-05 23.7 22.2 0.0014 18.7 3.3 3.2 2 1 1 3 3 3 2 PHD-like zinc-binding domain C1_1 PF00130.17 GAM18103.1 - 0.008 15.8 5.1 0.008 15.8 3.6 3.5 4 1 0 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 GAM18103.1 - 0.027 14.4 22.4 0.034 14.1 3.2 3.2 2 1 1 3 3 3 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.1 GAM18103.1 - 0.82 9.4 19.5 0.19 11.4 3.0 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 GAM18103.1 - 3.1 7.8 15.3 18 5.4 2.4 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.1 GAM18103.1 - 3.9 7.3 20.4 1.7 8.5 2.7 3.3 2 1 1 3 3 3 0 Ring finger domain Glyco_transf_49 PF13896.1 GAM18104.1 - 2.8e-42 144.9 1.9 3.3e-35 121.7 0.6 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.21 GAM18104.1 - 0.00028 20.6 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 GAM18104.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PARP PF00644.15 GAM18105.1 - 1.3e-30 106.3 1.0 7.5e-30 103.9 0.7 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAM18105.1 - 8.7e-09 35.1 0.7 1.8e-08 34.1 0.2 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain FAM92 PF06730.6 GAM18105.1 - 0.0032 16.8 0.0 0.0081 15.5 0.0 1.6 1 0 0 1 1 1 1 FAM92 protein Nuc_recep-AF1 PF11825.3 GAM18105.1 - 0.22 11.4 4.5 0.49 10.3 0.1 3.2 4 0 0 4 4 4 0 Nuclear/hormone receptor activator site AF-1 Sec23_trunk PF04811.10 GAM18106.1 - 1.7e-15 57.0 0.0 4.5e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM18106.1 - 6.7e-11 41.5 0.1 1.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAM18106.1 - 3.4e-06 27.4 0.0 8.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM18106.1 - 0.026 14.0 0.6 0.069 12.7 0.4 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF58 PF01882.13 GAM18106.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF58 FNIP PF05725.7 GAM18107.1 - 4.3e-45 151.4 26.3 5.6e-13 48.6 1.8 8.7 7 3 2 9 9 9 7 FNIP Repeat FNIP PF05725.7 GAM18108.1 - 1.3e-27 95.4 24.9 5e-13 48.7 0.1 7.7 9 0 0 9 9 9 5 FNIP Repeat LRR_8 PF13855.1 GAM18108.1 - 0.48 10.2 11.1 0.38 10.5 0.6 4.8 4 2 1 5 5 5 0 Leucine rich repeat FNIP PF05725.7 GAM18109.1 - 1.4e-12 47.3 0.1 6.6e-07 29.1 0.0 3.1 2 1 1 3 3 3 2 FNIP Repeat FNIP PF05725.7 GAM18110.1 - 9.3e-28 95.9 16.3 2.1e-13 49.9 0.1 4.1 4 2 2 6 6 6 3 FNIP Repeat Lipoprotein_15 PF03640.10 GAM18111.1 - 2.5e-26 90.8 0.4 3.3e-10 39.2 0.0 4.0 4 0 0 4 4 4 3 Secreted repeat of unknown function PH_11 PF15413.1 GAM18111.1 - 0.045 13.9 0.1 0.47 10.7 0.0 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Nucleo_P87 PF07267.6 GAM18114.1 - 0.021 13.5 1.9 0.035 12.8 1.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BSP_II PF05432.6 GAM18114.1 - 0.056 12.7 7.1 0.13 11.5 4.9 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.6 GAM18114.1 - 0.3 10.8 6.1 0.055 13.2 0.6 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 GAM18114.1 - 1.4 8.4 10.7 0.13 11.7 2.4 2.4 3 0 0 3 3 3 0 Nucleoplasmin PBP1_TM PF14812.1 GAM18114.1 - 3.2 8.1 12.3 1.3 9.3 3.6 2.9 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 GAM18114.1 - 8.2 6.0 10.5 0.16 11.6 1.3 2.5 3 0 0 3 3 3 0 FAM176 family FNIP PF05725.7 GAM18116.1 - 3.7e-99 324.4 36.8 8.6e-13 48.0 0.1 13.1 11 3 4 15 15 15 12 FNIP Repeat LSM PF01423.17 GAM18118.1 - 2.3e-17 62.2 0.1 2.8e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Methyltransf_4 PF02390.12 GAM18119.1 - 5.9e-28 97.2 0.0 1.4e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PPR_2 PF13041.1 GAM18119.1 - 4e-15 55.5 0.4 2.3e-07 30.6 0.0 4.2 1 1 2 4 4 4 3 PPR repeat family PPR PF01535.15 GAM18119.1 - 6.2e-10 38.3 0.5 0.00033 20.4 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 GAM18119.1 - 1.7e-09 37.1 0.2 0.00029 20.8 0.0 5.2 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 GAM18119.1 - 1.1e-07 31.1 0.1 0.0027 17.1 0.0 3.6 3 0 0 3 3 3 2 PPR repeat Med3 PF11593.3 GAM18119.1 - 0.17 11.1 21.5 0.27 10.4 14.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal IER PF05760.7 GAM18119.1 - 1.9 8.3 12.3 3.5 7.4 8.5 1.5 1 0 0 1 1 1 0 Immediate early response protein (IER) Nucleoporin_FG PF13634.1 GAM18120.1 - 5.7e-12 45.8 229.6 3.3e-05 24.0 32.6 6.3 1 1 4 5 5 5 3 Nucleoporin FG repeat region BRAP2 PF07576.7 GAM18121.1 - 4.6e-25 87.3 0.2 1.8e-24 85.4 0.2 2.0 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 GAM18121.1 - 5.1e-19 68.1 6.9 1.3e-18 66.8 4.8 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 GAM18121.1 - 3.8e-10 39.4 10.4 3.8e-10 39.4 7.2 2.3 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM18121.1 - 8e-05 22.6 5.0 8e-05 22.6 3.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM18121.1 - 0.00012 21.7 7.7 0.00012 21.7 5.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM18121.1 - 0.00019 21.0 8.0 0.00019 21.0 5.6 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM18121.1 - 0.00045 20.1 9.1 0.00045 20.1 6.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 GAM18121.1 - 0.0029 17.1 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 GAM18121.1 - 0.0031 17.3 5.1 0.0031 17.3 3.5 2.4 1 1 0 2 2 2 1 Putative GTPase activating protein for Arf zf-RING_4 PF14570.1 GAM18121.1 - 0.0046 16.5 2.9 0.0046 16.5 2.0 2.1 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 GAM18121.1 - 0.012 15.4 6.8 0.012 15.4 4.7 1.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAM18121.1 - 0.014 15.1 1.6 0.014 15.1 1.1 2.9 2 0 0 2 2 2 0 RING-type zinc-finger NHase_beta PF02211.10 GAM18121.1 - 0.021 14.5 3.1 1.3 8.7 0.7 2.2 2 0 0 2 2 2 0 Nitrile hydratase beta subunit PHF5 PF03660.9 GAM18121.1 - 0.29 11.1 8.9 0.33 11.0 5.1 1.9 2 0 0 2 2 2 0 PHF5-like protein TMPIT PF07851.8 GAM18121.1 - 1.8 7.5 7.8 11 5.0 5.9 1.8 2 0 0 2 2 2 0 TMPIT-like protein DUF974 PF06159.8 GAM18122.1 - 4.8e-67 226.0 0.0 6.6e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.17 GAM18122.1 - 0.049 13.6 0.3 18 5.4 0.0 2.9 2 1 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Trs65 PF12735.2 GAM18122.1 - 0.067 12.4 4.8 0.07 12.4 0.0 3.0 2 1 1 3 3 3 0 TRAPP trafficking subunit Trs65 DHO_dh PF01180.16 GAM18123.1 - 3.8e-34 117.9 0.0 1.6e-33 115.9 0.0 2.1 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.1 GAM18123.1 - 4.2e-31 106.8 0.8 4.2e-31 106.8 0.5 2.6 2 2 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.1 GAM18123.1 - 2.6e-22 78.4 13.2 2.6e-22 78.4 9.1 3.7 3 1 1 4 4 4 1 4Fe-4S dicluster domain Dus PF01207.12 GAM18123.1 - 1.4e-07 30.6 0.1 4.6e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_10 PF13237.1 GAM18123.1 - 2.4e-06 27.2 10.5 2.4e-06 27.2 7.3 3.6 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 GAM18123.1 - 6.2e-06 26.5 9.5 6.2e-06 26.5 6.6 3.8 4 0 0 4 4 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 GAM18123.1 - 2.4e-05 23.9 32.5 0.00013 21.6 1.2 4.8 5 0 0 5 5 4 3 4Fe-4S binding domain NAD_binding_8 PF13450.1 GAM18123.1 - 4.6e-05 23.3 0.0 0.00016 21.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Fer4_8 PF13183.1 GAM18123.1 - 6.2e-05 22.9 21.3 0.034 14.1 2.4 4.5 4 0 0 4 4 4 3 4Fe-4S dicluster domain Pyr_redox PF00070.22 GAM18123.1 - 0.00038 20.8 0.1 0.84 10.0 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.1 GAM18123.1 - 0.00048 20.3 13.3 0.00048 20.3 9.2 3.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4 PF00037.22 GAM18123.1 - 0.0016 17.9 14.9 0.0027 17.2 2.9 4.9 5 0 0 5 5 5 2 4Fe-4S binding domain Pyr_redox_3 PF13738.1 GAM18123.1 - 0.002 18.2 0.0 1 9.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.2 GAM18123.1 - 0.0021 17.8 1.6 0.0021 17.8 1.1 5.3 6 0 0 6 6 5 3 4Fe-4S binding domain Fer4_15 PF13459.1 GAM18123.1 - 0.0023 18.4 8.1 0.15 12.6 0.6 3.3 2 0 0 2 2 2 2 4Fe-4S single cluster domain Pyr_redox_2 PF07992.9 GAM18123.1 - 0.0067 16.3 0.1 4.5 7.1 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_11 PF13247.1 GAM18123.1 - 0.038 13.8 9.0 1.7 8.5 0.2 2.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 GAM18123.1 - 0.055 13.8 24.5 0.2 12.0 0.7 4.3 3 1 1 4 4 4 0 4Fe-4S dicluster domain Metallophos PF00149.23 GAM18126.1 - 3e-08 33.3 0.4 5.9e-08 32.3 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Histone PF00125.19 GAM18127.1 - 4.2e-17 62.0 0.3 6.4e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM18127.1 - 0.0033 17.4 0.4 0.0093 16.0 0.3 1.9 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 GAM18127.1 - 0.0089 16.1 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF2890 PF11081.3 GAM18127.1 - 0.021 14.8 0.8 0.031 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) MOR2-PAG1_N PF14222.1 GAM18127.1 - 0.079 11.6 0.5 0.079 11.6 0.3 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal RPA_C PF08784.6 GAM18127.1 - 0.24 11.8 1.9 3.7 8.0 1.3 2.1 1 1 0 1 1 1 0 Replication protein A C terminal FokI_C PF02980.11 GAM18127.1 - 0.51 9.9 4.8 1.2 8.7 2.8 1.8 1 1 1 2 2 2 0 Restriction endonuclease FokI, catalytic domain eIF-4B PF06273.6 GAM18127.1 - 2.1 6.9 7.8 3.1 6.4 5.4 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Histone PF00125.19 GAM18128.1 - 2.4e-16 59.5 2.9 5.1e-16 58.5 2.0 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM18128.1 - 0.00011 22.2 0.2 0.00035 20.5 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 GAM18128.1 - 0.013 15.7 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 GAM18128.1 - 0.04 14.1 0.2 0.073 13.2 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S Methyltransf_2 PF00891.13 GAM18130.1 - 7.9e-49 166.0 0.0 1.1e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 GAM18130.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator HTH_24 PF13412.1 GAM18130.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 GAM18130.1 - 0.043 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_AraC PF00165.18 GAM18130.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family IL4 PF00727.13 GAM18130.1 - 0.068 13.0 0.1 1.7 8.5 0.0 2.7 2 1 0 2 2 2 0 Interleukin 4 Pkinase PF00069.20 GAM18131.1 - 1e-58 198.5 0.0 3e-58 197.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18131.1 - 1.9e-42 145.1 0.0 4.8e-42 143.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM18131.1 - 1e-05 24.7 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM18131.1 - 0.0039 16.9 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 GAM18132.1 - 1.4e-67 227.5 0.0 1.4e-67 227.5 0.0 4.5 4 1 1 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18132.1 - 9.4e-49 165.8 3.0 1.4e-47 162.0 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 GAM18132.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.7 4 2 0 4 4 4 0 Phosphotransferase enzyme family DDE_Tnp_1_7 PF13843.1 GAM18133.1 - 1.5e-33 116.3 0.0 2.4e-33 115.6 0.0 1.3 1 1 0 1 1 1 1 Transposase IS4 DUF4404 PF14357.1 GAM18133.1 - 0.13 12.7 0.8 11 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) VWA_2 PF13519.1 GAM18134.1 - 1.6e-17 64.1 0.0 8.3e-13 48.7 0.0 3.8 3 1 0 3 3 3 2 von Willebrand factor type A domain VWA PF00092.23 GAM18134.1 - 1.2e-08 34.8 1.8 3.8e-08 33.2 0.0 2.8 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 GAM18134.1 - 0.024 13.7 2.1 0.93 8.5 0.0 3.4 3 1 0 3 3 3 0 VWA domain containing CoxE-like protein F-box-like PF12937.2 GAM18134.1 - 0.042 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 GAM18134.1 - 0.065 12.9 0.2 0.28 10.8 0.1 2.1 1 0 0 1 1 1 0 F-box domain DUF2894 PF11445.3 GAM18134.1 - 0.28 11.4 6.2 0.55 10.4 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) FNIP PF05725.7 GAM18135.1 - 1.6e-57 191.1 22.5 4.1e-12 45.8 0.0 10.6 6 3 8 14 14 14 12 FNIP Repeat LRR_5 PF13306.1 GAM18135.1 - 8.5e-05 22.2 0.0 0.0027 17.4 0.0 3.0 3 1 0 3 3 3 1 Leucine rich repeats (6 copies) AAA PF00004.24 GAM18136.1 - 4.9e-38 130.3 0.0 1.4e-37 128.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAM18136.1 - 2e-08 33.9 2.5 2.4e-08 33.7 0.0 2.5 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 GAM18136.1 - 2.1e-05 23.7 0.0 4.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM18136.1 - 5.6e-05 23.2 0.1 0.0018 18.4 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAM18136.1 - 9.1e-05 22.2 0.0 0.00086 19.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 GAM18136.1 - 0.001 17.8 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 GAM18136.1 - 0.0033 17.3 0.2 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 GAM18136.1 - 0.0045 17.2 0.4 0.016 15.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAM18136.1 - 0.0057 17.4 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 GAM18136.1 - 0.019 14.3 0.0 0.06 12.7 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM18136.1 - 0.021 13.9 0.1 0.062 12.4 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAM18136.1 - 0.025 13.9 0.7 0.46 9.8 0.1 2.6 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 GAM18136.1 - 0.044 13.9 0.0 0.18 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 GAM18136.1 - 0.051 13.5 0.6 0.24 11.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 GAM18136.1 - 0.085 12.6 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 GAM18136.1 - 0.085 12.7 0.0 0.66 9.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain SKI PF01202.17 GAM18136.1 - 9.1 6.1 8.0 0.66 9.8 0.1 2.9 3 0 0 3 3 3 0 Shikimate kinase VWA_2 PF13519.1 GAM18137.1 - 3.4e-13 50.0 0.6 1e-12 48.5 0.4 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 GAM18137.1 - 4.4e-05 22.7 0.1 0.2 10.7 0.0 2.4 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein Sec23_BS PF08033.7 GAM18137.1 - 0.0036 17.7 2.0 0.02 15.3 0.7 2.7 2 1 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM18137.1 - 0.15 11.6 0.9 1 8.9 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger ERG4_ERG24 PF01222.12 GAM18138.1 - 1.2e-120 403.0 12.9 1.4e-120 402.7 8.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 GAM18138.1 - 7e-05 22.2 1.6 0.00012 21.4 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ras PF00071.17 GAM18139.1 - 2.8e-58 195.8 0.3 3.6e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM18139.1 - 4.5e-22 78.7 0.1 7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM18139.1 - 4.8e-14 51.9 0.3 5.4e-14 51.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM18139.1 - 9.2e-07 28.4 0.1 5.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM18139.1 - 5.4e-06 25.7 0.1 2.5e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM18139.1 - 1.3e-05 24.4 0.2 1.6e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM18139.1 - 0.00031 20.6 0.1 0.00048 20.0 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM18139.1 - 0.0079 15.4 0.1 0.14 11.4 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B F5_F8_type_C PF00754.20 GAM18140.1 - 5.1e-24 84.5 1.2 6.1e-24 84.2 0.9 1.0 1 0 0 1 1 1 1 F5/8 type C domain CHB_HEX_C_1 PF13290.1 GAM18140.1 - 0.031 14.0 0.6 0.055 13.2 0.4 1.4 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain MMR_HSR1 PF01926.18 GAM18141.1 - 2.8e-15 56.2 0.0 4.7e-14 52.3 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM18141.1 - 3.8e-05 23.0 0.0 7.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM18141.1 - 6.9e-05 22.0 0.0 0.00016 20.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Parvo_NS1 PF01057.12 GAM18141.1 - 9.2e-05 21.4 0.0 0.00017 20.5 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IIGP PF05049.8 GAM18141.1 - 0.0022 16.8 0.0 0.0044 15.8 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.22 GAM18141.1 - 0.0024 17.3 0.0 0.54 9.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 GAM18141.1 - 0.05 13.1 0.1 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 GAM18141.1 - 0.051 13.4 3.2 2.6 7.8 0.0 3.6 3 1 1 4 4 4 0 Dynamin family SRPRB PF09439.5 GAM18141.1 - 0.088 12.0 0.0 3.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 GAM18141.1 - 0.097 12.2 1.5 6.6 6.1 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pex14_N PF04695.8 GAM18141.1 - 0.13 12.2 13.0 0.066 13.2 1.1 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_16 PF13191.1 GAM18141.1 - 0.24 11.3 3.5 0.25 11.3 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain HAND PF09110.6 GAM18141.1 - 0.53 10.6 4.5 2.8 8.3 0.4 2.4 2 0 0 2 2 2 0 HAND CDK2AP PF09806.4 GAM18141.1 - 3.8 7.7 17.2 0.51 10.5 5.1 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PEPCK_ATP PF01293.15 GAM18142.1 - 2.9e-221 734.9 0.0 3.4e-221 734.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 GAM18142.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM18142.1 - 0.12 11.9 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM18142.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Rap_GAP PF02145.10 GAM18145.1 - 2.2e-57 193.5 0.1 3.9e-57 192.6 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP PH PF00169.24 GAM18145.1 - 1.8e-18 66.6 9.4 3.1e-05 24.0 0.1 3.8 4 0 0 4 4 4 3 PH domain PH_11 PF15413.1 GAM18145.1 - 3.1e-09 37.0 12.4 4.2e-05 23.7 0.3 4.5 3 1 0 3 3 3 3 Pleckstrin homology domain Mcp5_PH PF12814.2 GAM18145.1 - 0.0095 15.8 0.3 0.023 14.6 0.2 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology MatE PF01554.13 GAM18146.1 - 8.4e-62 207.5 33.6 5.7e-35 120.3 6.2 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 GAM18146.1 - 1.4e-07 31.4 15.3 1.5e-06 28.0 4.0 3.8 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain EGF_2 PF07974.8 GAM18148.1 - 0.0016 18.5 9.3 0.0031 17.6 6.5 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 GAM18148.1 - 0.049 13.7 3.5 0.1 12.6 2.5 1.5 1 0 0 1 1 1 0 EB module UCH PF00443.24 GAM18149.1 - 1.9e-61 207.5 1.1 8e-61 205.4 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM18149.1 - 1.9e-25 89.9 0.0 6.8e-24 84.8 0.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAM18149.1 - 2.7e-10 40.2 11.6 2.7e-10 40.2 8.0 3.2 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein HlyIII PF03006.15 GAM18151.1 - 9.6e-44 149.4 25.3 1.3e-43 148.9 17.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related FNIP PF05725.7 GAM18152.1 - 0.014 15.3 34.0 0.023 14.6 0.1 7.5 7 1 1 8 8 8 0 FNIP Repeat Mg296 PF09644.5 GAM18152.1 - 0.078 12.8 2.8 0.64 9.8 0.5 2.5 2 0 0 2 2 2 0 Mg296 protein PB1 PF00564.19 GAM18153.1 - 1.1e-09 37.7 0.0 2.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain MA3 PF02847.12 GAM18154.1 - 0.44 10.2 4.6 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 MA3 domain HSP70 PF00012.15 GAM18155.1 - 1.7e-261 868.4 11.4 2e-261 868.2 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM18155.1 - 4.4e-16 58.3 0.1 4e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 GAM18155.1 - 0.0018 17.1 0.4 0.11 11.3 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Pox_D5 PF03288.11 GAM18155.1 - 0.022 14.9 0.2 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like DDE_Tnp_IS1 PF03400.8 GAM18155.1 - 0.026 14.6 0.0 0.59 10.2 0.0 2.5 2 0 0 2 2 2 0 IS1 transposase DUF592 PF04574.8 GAM18155.1 - 0.037 13.5 0.6 0.037 13.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF592) FGGY_C PF02782.11 GAM18155.1 - 0.052 13.1 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 GAM18155.1 - 0.07 12.2 2.9 0.37 9.8 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 GAM18155.1 - 0.47 10.3 7.4 2 8.2 2.4 3.5 2 1 0 2 2 2 0 Cell division protein FtsA Radial_spoke_3 PF06098.6 GAM18155.1 - 1.9 7.4 12.4 0.051 12.5 2.9 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 WD-3 PF09765.4 GAM18156.1 - 8.9e-39 133.4 0.1 8.5e-31 107.3 0.0 3.0 1 1 1 2 2 2 2 WD-repeat region FANCL_C PF11793.3 GAM18156.1 - 5e-27 93.6 3.6 7.7e-27 93.0 2.5 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 GAM18156.1 - 4.6e-05 23.1 6.3 8.7e-05 22.2 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.1 GAM18156.1 - 0.0039 17.3 0.8 0.0068 16.5 0.6 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-rbx1 PF12678.2 GAM18156.1 - 0.0047 17.0 2.6 0.01 15.9 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-HC5HC2H_2 PF13832.1 GAM18156.1 - 0.023 14.6 0.2 0.042 13.8 0.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Baculo_RING PF05883.6 GAM18156.1 - 0.082 12.7 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RWD PF05773.17 GAM18156.1 - 0.11 12.4 0.1 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 RWD domain zf-C3HC4_2 PF13923.1 GAM18156.1 - 0.48 10.4 4.4 1.5 8.9 3.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 GAM18156.1 - 0.82 9.7 4.6 1.6 8.7 3.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 GAM18156.1 - 1.9 8.4 5.1 6.6 6.6 3.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TMEM154 PF15102.1 GAM18158.1 - 0.00092 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.1 GAM18158.1 - 0.005 17.0 11.6 0.005 17.0 8.1 1.5 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 GAM18158.1 - 0.018 15.4 1.0 0.035 14.4 0.7 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 GAM18158.1 - 0.06 13.0 0.1 0.073 12.7 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 IncA PF04156.9 GAM18158.1 - 0.06 12.9 3.4 0.083 12.4 2.4 1.1 1 0 0 1 1 1 0 IncA protein NACHT PF05729.7 GAM18159.1 - 0.03 13.9 0.0 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain KaiC PF06745.8 GAM18159.1 - 0.035 13.2 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 GAM18159.1 - 0.099 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM18159.1 - 0.11 12.1 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3336 PF11815.3 GAM18160.1 - 5.6e-38 129.7 2.3 5.6e-38 129.7 1.6 2.5 3 0 0 3 3 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 GAM18160.1 - 3.4e-25 89.1 0.0 6.6e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ABC2_membrane_3 PF12698.2 GAM18160.1 - 0.0013 17.8 0.6 0.0024 16.9 0.4 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein SprA-related PF12118.3 GAM18160.1 - 0.029 13.7 17.1 0.044 13.1 11.9 1.2 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.10 GAM18160.1 - 0.041 12.5 3.1 0.059 12.0 2.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Activator_LAG-3 PF11498.3 GAM18160.1 - 0.18 10.5 26.3 0.28 9.8 18.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BAF1_ABF1 PF04684.8 GAM18160.1 - 0.18 10.6 30.0 0.28 9.9 20.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PspB PF06667.7 GAM18160.1 - 0.55 10.1 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 1 0 Phage shock protein B Peptidase_S49_N PF08496.5 GAM18160.1 - 0.84 9.4 8.8 20 4.9 7.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SelP_N PF04592.9 GAM18160.1 - 0.95 8.8 18.2 3.2 7.0 10.6 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Suf PF05843.9 GAM18160.1 - 1.8 8.1 13.8 3.1 7.4 9.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK5_activator PF03261.10 GAM18160.1 - 3 7.1 15.0 4.6 6.4 10.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CDC45 PF02724.9 GAM18161.1 - 0.097 10.6 11.5 0.15 10.0 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec20 PF03908.8 GAM18162.1 - 4.7e-15 55.0 2.7 4.7e-15 55.0 1.8 2.6 2 1 0 2 2 2 1 Sec20 T2SJ PF11612.3 GAM18162.1 - 0.048 13.4 0.1 0.88 9.2 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J KilA-N PF04383.8 GAM18162.1 - 0.089 12.4 0.6 0.33 10.5 0.8 1.8 2 1 0 2 2 2 0 KilA-N domain DUF2721 PF11026.3 GAM18162.1 - 0.32 10.6 2.2 0.37 10.4 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Prominin PF05478.6 GAM18162.1 - 0.78 7.1 12.3 5.2 4.4 8.6 2.1 1 1 0 1 1 1 0 Prominin 7TM_GPCR_Srj PF10319.4 GAM18162.1 - 3.2 6.7 6.5 0.12 11.4 0.3 1.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj Allexi_40kDa PF05549.6 GAM18162.1 - 4.1 6.6 9.9 1.9 7.7 1.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein CHCH PF06747.8 GAM18163.1 - 0.00065 19.5 0.8 0.0017 18.2 0.6 1.8 1 0 0 1 1 1 1 CHCH domain DUF3128 PF11326.3 GAM18163.1 - 0.51 10.4 3.0 5.7 7.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) DB PF01682.14 GAM18163.1 - 0.57 10.2 7.3 0.74 9.8 5.1 1.3 1 0 0 1 1 1 0 DB module UCR_hinge PF02320.11 GAM18163.1 - 0.8 9.6 7.0 13 5.7 4.8 2.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 GAM18163.1 - 2.1 8.1 9.0 3.7 7.3 2.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pkinase PF00069.20 GAM18164.1 - 2.3e-56 190.8 0.0 1.8e-55 187.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18164.1 - 5.9e-25 87.8 0.1 1.1e-17 64.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM18164.1 - 0.00023 20.2 0.1 0.014 14.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 GAM18164.1 - 0.0023 17.7 0.0 0.0044 16.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM18164.1 - 0.0033 16.3 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 SOG2 PF10428.4 GAM18164.1 - 5.9 5.4 35.7 1.6 7.3 7.3 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein DUF4207 PF13904.1 GAM18165.1 - 0.0049 16.2 25.8 0.0077 15.6 17.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) AAA_23 PF13476.1 GAM18165.1 - 0.0052 17.1 7.4 0.0066 16.7 5.2 1.2 1 0 0 1 1 1 1 AAA domain Med15 PF09606.5 GAM18165.1 - 0.011 14.0 52.5 0.016 13.4 36.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 GAM18165.1 - 0.015 14.6 39.2 0.02 14.2 27.2 1.2 1 0 0 1 1 1 0 SprA-related family Radical_SAM_N PF08497.5 GAM18165.1 - 0.073 11.9 4.4 0.086 11.7 3.0 1.2 1 0 0 1 1 1 0 Radical SAM N-terminal DUF605 PF04652.11 GAM18165.1 - 0.079 12.3 37.2 0.12 11.7 25.8 1.3 1 0 0 1 1 1 0 Vta1 like RAP1 PF07218.6 GAM18165.1 - 0.2 9.7 13.3 0.25 9.3 9.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2126 PF09899.4 GAM18165.1 - 1.3 6.9 11.8 1.8 6.4 8.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) HemX PF04375.9 GAM18165.1 - 2.5 6.6 23.5 1.7 7.1 15.4 1.3 1 1 0 1 1 1 0 HemX RR_TM4-6 PF06459.7 GAM18165.1 - 4.7 7.0 14.1 6.6 6.5 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 GAM18165.1 - 6.2 6.5 12.2 10 5.8 8.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SSP160 PF06933.6 GAM18165.1 - 7 4.4 25.6 10 3.9 17.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RNase_PH PF01138.16 GAM18166.1 - 4.2e-31 107.9 0.1 5.9e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAM18166.1 - 1.3e-05 25.0 0.1 2.9e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Dor1 PF04124.7 GAM18167.1 - 2.6e-77 259.5 10.6 3.1e-77 259.3 7.4 1.0 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 GAM18167.1 - 7.5e-08 32.3 6.7 1.8e-07 31.0 4.6 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 DUF2450 PF10475.4 GAM18167.1 - 1.8e-06 27.0 7.3 3.1e-06 26.2 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 GAM18167.1 - 0.025 14.2 0.6 0.025 14.2 0.4 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Vps51 PF08700.6 GAM18167.1 - 0.049 13.4 8.2 0.066 13.0 1.2 2.6 2 0 0 2 2 2 0 Vps51/Vps67 Carbpep_Y_N PF05388.6 GAM18167.1 - 0.4 10.8 3.1 2.3 8.4 0.0 3.0 3 1 0 3 3 3 0 Carboxypeptidase Y pro-peptide CPL PF08144.6 GAM18168.1 - 3.4e-13 49.6 2.3 5.6e-12 45.7 0.0 3.6 2 1 1 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 GAM18168.1 - 0.00057 19.2 0.1 9.1 5.9 0.0 6.0 6 0 0 6 6 6 1 Pumilio-family RNA binding repeat DUF3439 PF11921.3 GAM18168.1 - 0.3 10.8 5.1 0.64 9.7 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rtf2 PF04641.7 GAM18169.1 - 6e-69 232.1 10.6 1.2e-68 231.1 7.3 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 GAM18169.1 - 0.0017 18.0 0.3 0.0056 16.3 0.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 GAM18169.1 - 0.016 14.7 0.5 4.9 6.7 0.3 2.8 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 GAM18169.1 - 0.029 13.9 0.6 0.068 12.7 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 GAM18169.1 - 0.064 13.1 0.5 0.99 9.2 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain DUF3439 PF11921.3 GAM18169.1 - 0.48 10.1 18.7 0.15 11.8 9.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM18169.1 - 2.2 8.0 20.6 0.2 11.4 11.0 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein FAM176 PF14851.1 GAM18169.1 - 2.3 7.8 6.6 4.9 6.8 4.5 1.6 1 0 0 1 1 1 0 FAM176 family DUF572 PF04502.8 GAM18169.1 - 7.8 5.6 19.1 13 4.9 13.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) NST1 PF13945.1 GAM18169.1 - 8 6.4 20.7 0.89 9.6 11.2 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator PBP1_TM PF14812.1 GAM18170.1 - 0.0088 16.3 7.2 0.0095 16.2 5.0 1.0 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 GAM18170.1 - 0.19 11.2 5.9 0.19 11.2 4.1 1.0 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 GAM18170.1 - 0.46 10.7 6.0 0.47 10.7 4.2 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 GAM18170.1 - 0.6 9.6 6.0 0.57 9.7 4.1 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 GAM18170.1 - 0.82 9.8 6.1 0.84 9.8 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 GAM18170.1 - 1.6 8.4 4.7 1.6 8.5 3.3 1.0 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4366 PF14283.1 GAM18170.1 - 7.8 5.8 8.2 8.6 5.7 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tfb2 PF03849.9 GAM18172.1 - 1.9e-103 345.9 10.0 2.2e-103 345.7 6.9 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 DUF445 PF04286.7 GAM18172.1 - 0.0088 15.6 1.3 0.5 9.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF445) Helicase_C_3 PF13625.1 GAM18172.1 - 0.033 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain PRESAN PF09687.5 GAM18172.1 - 2.7 8.0 8.2 0.092 12.8 0.5 2.4 3 0 0 3 3 3 0 Plasmodium RESA N-terminal FNIP PF05725.7 GAM18173.1 - 3.9e-86 282.7 30.8 5e-13 48.7 0.2 9.9 5 2 5 11 11 11 11 FNIP Repeat Stress-antifung PF01657.12 GAM18174.1 - 0.022 15.0 0.3 0.051 13.9 0.2 1.6 1 0 0 1 1 1 0 Salt stress response/antifungal EF-hand_2 PF09068.6 GAM18175.1 - 0.087 12.9 0.6 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 EF hand WD40 PF00400.27 GAM18177.1 - 2.7e-10 39.7 38.2 0.043 13.7 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat C1_1 PF00130.17 GAM18177.1 - 0.0082 15.8 11.2 0.021 14.5 7.7 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 GAM18177.1 - 0.047 13.7 3.3 0.11 12.5 2.3 1.7 1 0 0 1 1 1 0 C1-like domain C1_4 PF07975.7 GAM18177.1 - 0.075 13.0 5.0 0.22 11.5 3.5 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain C1_2 PF03107.11 GAM18177.1 - 0.37 10.9 7.6 0.072 13.2 2.5 2.0 2 0 0 2 2 2 0 C1 domain RasGEF PF00617.14 GAM18179.1 - 4.2e-55 186.4 0.6 7.8e-55 185.5 0.4 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM18179.1 - 2.7e-20 72.4 1.8 4.4e-20 71.7 0.2 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif DEP PF00610.16 GAM18179.1 - 6e-15 54.7 0.0 1.4e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ammonium_transp PF00909.16 GAM18180.1 - 1.5e-48 165.3 23.8 1.8e-48 164.9 16.5 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Big_3 PF07523.7 GAM18181.1 - 1.7 8.7 5.0 1.2 9.2 1.6 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) HSP70 PF00012.15 GAM18183.1 - 5.7e-139 463.7 0.0 6.8e-139 463.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM18183.1 - 5.5e-07 28.4 0.0 8.7e-07 27.8 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein SnoaL_2 PF12680.2 GAM18184.1 - 1.4e-06 28.5 0.0 1.6e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM18184.1 - 0.019 15.1 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DNA_pol3_delta2 PF13177.1 GAM18184.1 - 0.056 13.1 0.2 0.072 12.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit p450 PF00067.17 GAM18185.1 - 1.1e-104 350.5 1.2 1.2e-104 350.4 0.9 1.0 1 0 0 1 1 1 1 Cytochrome P450 AhpC-TSA PF00578.16 GAM18186.1 - 9.3e-44 148.0 0.0 1.2e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM18186.1 - 1.9e-26 92.3 0.0 2.7e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 GAM18186.1 - 0.00042 20.2 0.0 0.002 18.0 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 GAM18186.1 - 0.00067 19.1 0.0 0.00079 18.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.9 GAM18186.1 - 0.0072 15.9 0.3 0.066 12.8 0.1 2.2 1 1 1 2 2 2 1 SCO1/SenC GSHPx PF00255.14 GAM18186.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase Nucleoside_tran PF01733.13 GAM18186.1 - 0.1 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter WD40 PF00400.27 GAM18187.1 - 4.4e-61 200.7 33.2 1.5e-07 30.9 2.1 13.1 13 1 0 13 13 13 10 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM18187.1 - 0.0019 16.5 0.2 0.059 11.6 0.0 2.9 2 1 1 3 3 3 1 Cytochrome D1 heme domain ABC2_membrane PF01061.19 GAM18188.1 - 3.8e-82 274.5 57.5 2.8e-44 150.7 15.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM18188.1 - 2.7e-49 167.0 0.1 1.5e-23 83.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM18188.1 - 2.6e-09 36.6 0.1 0.00011 21.5 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM18188.1 - 5.1e-09 36.4 2.8 0.061 13.2 0.0 5.1 4 1 0 5 5 5 2 AAA domain DUF258 PF03193.11 GAM18188.1 - 7.7e-08 31.6 0.0 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAM18188.1 - 1.9e-07 31.0 0.1 0.009 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAM18188.1 - 2.2e-07 30.2 0.1 0.16 10.9 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain AAA_25 PF13481.1 GAM18188.1 - 2.4e-07 30.3 0.0 0.035 13.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAM18188.1 - 2.7e-07 30.7 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAM18188.1 - 1.7e-06 28.2 0.0 0.036 14.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain PDR_CDR PF06422.7 GAM18188.1 - 4.3e-06 26.3 1.0 0.095 12.3 0.1 2.7 2 0 0 2 2 2 2 CDR ABC transporter AAA PF00004.24 GAM18188.1 - 9.2e-06 25.8 0.1 0.0078 16.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM18188.1 - 1.2e-05 26.0 0.0 0.15 12.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM18188.1 - 1.4e-05 24.4 0.3 0.0028 17.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM18188.1 - 2.5e-05 24.5 0.1 0.29 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM18188.1 - 6.7e-05 22.8 0.9 0.38 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM18188.1 - 9.7e-05 22.5 0.0 0.73 10.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 GAM18188.1 - 0.00012 21.8 0.1 0.22 11.2 0.0 3.0 4 0 0 4 4 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 GAM18188.1 - 0.00026 20.9 0.0 0.86 9.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase UPF0079 PF02367.12 GAM18188.1 - 0.00047 19.7 0.6 0.4 10.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 GAM18188.1 - 0.00068 18.4 0.1 0.76 8.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein NACHT PF05729.7 GAM18188.1 - 0.001 18.7 1.0 0.73 9.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.1 GAM18188.1 - 0.001 18.9 0.6 0.21 11.5 0.0 3.3 4 0 0 4 4 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 GAM18188.1 - 0.0014 17.6 0.2 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 GAM18188.1 - 0.0037 16.7 0.1 3.6 6.9 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAM18188.1 - 0.0055 16.4 0.1 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 GAM18188.1 - 0.0062 15.6 2.2 0.14 11.2 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.14 GAM18188.1 - 0.0065 15.9 0.4 1.4 8.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 GAM18188.1 - 0.0069 16.1 1.5 0.83 9.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 GAM18188.1 - 0.0084 16.4 1.9 1.9 8.7 0.0 2.9 2 1 1 3 3 2 1 AAA domain AAA_30 PF13604.1 GAM18188.1 - 0.011 15.3 0.1 4.4 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.6 GAM18188.1 - 0.012 15.1 2.0 0.38 10.3 0.1 3.2 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Miro PF08477.8 GAM18188.1 - 0.045 14.2 0.0 9.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 GAM18188.1 - 0.048 13.2 2.0 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 GAM18188.1 - 0.09 12.6 0.0 10 6.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 GAM18188.1 - 0.1 12.1 4.9 1.9 7.9 0.1 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 GAM18188.1 - 0.14 11.4 0.1 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Mg_chelatase PF01078.16 GAM18188.1 - 0.14 11.2 0.6 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 GAM18188.1 - 0.18 11.2 0.1 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FNIP PF05725.7 GAM18189.1 - 4.5e-53 176.9 15.2 4.2e-11 42.6 0.0 8.9 7 2 0 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM18189.1 - 0.0098 15.8 0.0 2.7 7.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1769) CENP-B_dimeris PF09026.5 GAM18189.1 - 0.029 14.5 2.7 0.066 13.4 1.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain OATP PF03137.15 GAM18190.1 - 0.0018 16.4 0.1 0.0029 15.7 0.0 1.3 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Mem_trans PF03547.13 GAM18190.1 - 0.013 13.7 0.1 0.024 12.9 0.0 1.5 1 1 0 1 1 1 0 Membrane transport protein DUF3464 PF11947.3 GAM18190.1 - 0.035 13.5 0.1 0.57 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) BatD PF13584.1 GAM18190.1 - 0.04 12.5 0.2 0.073 11.6 0.1 1.4 1 0 0 1 1 1 0 Oxygen tolerance DUF4337 PF14235.1 GAM18190.1 - 0.16 11.7 1.0 0.33 10.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF106 PF01956.11 GAM18190.1 - 0.29 10.6 5.9 0.26 10.7 3.2 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF1013 PF06242.6 GAM18190.1 - 0.54 10.2 4.8 1.1 9.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Peptidase_S49_N PF08496.5 GAM18190.1 - 1.8 8.3 6.5 1.3 8.8 3.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Flavodoxin_1 PF00258.20 GAM18192.1 - 2.7e-23 82.5 0.0 4.3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 GAM18192.1 - 0.0026 17.7 0.0 0.047 13.6 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain FAD_binding_1 PF00667.15 GAM18193.1 - 3.3e-35 121.5 0.0 4.3e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 GAM18193.1 - 1.3e-12 48.1 0.0 2.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4441 PF14536.1 GAM18193.1 - 0.018 15.0 0.8 0.05 13.5 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) DUF2613 PF11021.3 GAM18195.1 - 0.078 12.7 2.7 6.6 6.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) ArgK PF03308.11 GAM18196.1 - 0.0055 15.5 0.0 0.0098 14.7 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 GAM18196.1 - 0.012 15.7 0.0 0.085 12.9 0.0 2.4 3 1 0 3 3 3 0 AAA domain NACHT PF05729.7 GAM18196.1 - 0.025 14.2 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SAM_2 PF07647.12 GAM18196.1 - 0.031 14.1 0.0 0.081 12.7 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM18196.1 - 0.038 14.1 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Miro PF08477.8 GAM18196.1 - 0.043 14.3 0.0 0.71 10.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 GAM18196.1 - 0.05 13.0 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 GAM18196.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 GAM18196.1 - 0.16 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DDE_3 PF13358.1 GAM18197.1 - 1.3e-24 86.6 0.0 2.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_30 PF13604.1 GAM18197.1 - 0.19 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain U3_assoc_6 PF08640.6 GAM18198.1 - 3.5e-17 61.9 0.8 3.5e-17 61.9 0.6 2.8 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 GAM18198.1 - 0.0043 17.5 1.2 58 4.7 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 GAM18198.1 - 0.014 14.2 4.5 0.61 8.9 0.2 2.7 3 0 0 3 3 3 0 NRDE-2, necessary for RNA interference DPPIV_N PF00930.16 GAM18199.1 - 1.8e-70 237.3 7.7 3.5e-70 236.3 5.2 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 GAM18199.1 - 9.9e-46 155.6 0.0 1.9e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 GAM18199.1 - 3.9e-09 36.2 1.3 3.4e-07 29.9 0.1 3.0 2 1 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.2 GAM18199.1 - 3.7e-07 30.0 0.0 1.3e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 GAM18199.1 - 2.5e-06 27.1 0.2 0.00014 21.4 0.1 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 GAM18199.1 - 1e-05 25.5 0.0 2.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 GAM18199.1 - 0.0045 16.6 0.1 0.047 13.3 0.0 2.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 GAM18199.1 - 0.0077 14.7 0.0 0.46 8.9 0.0 2.2 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 GAM18199.1 - 0.042 13.2 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.6 GAM18199.1 - 0.047 12.4 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF3141 PF11339.3 GAM18199.1 - 0.096 11.0 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) FH2 PF02181.18 GAM18201.1 - 4.3e-81 272.6 8.8 4.3e-81 272.6 6.1 3.2 3 0 0 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.11 GAM18201.1 - 2.2e-34 118.6 2.1 4.1e-34 117.7 0.3 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAM18201.1 - 9.9e-23 80.4 0.3 2.7e-22 79.0 0.2 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Mnd1 PF03962.10 GAM18201.1 - 0.012 15.3 2.8 0.75 9.4 0.0 2.9 2 0 0 2 2 2 0 Mnd1 family FNIP PF05725.7 GAM18202.1 - 1.4e-20 72.9 11.3 5.4e-14 51.8 0.6 5.3 3 2 0 5 5 5 4 FNIP Repeat DUF1769 PF08588.5 GAM18202.1 - 0.14 12.1 0.2 3.4 7.7 0.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1769) KSHV_K1 PF11049.3 GAM18204.1 - 0.14 12.1 1.1 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus DAP3 PF10236.4 GAM18205.1 - 0.0001 21.3 0.0 0.00028 19.9 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 GAM18205.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 GAM18205.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 GAM18205.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AFG1_ATPase PF03969.11 GAM18205.1 - 0.033 13.0 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.7 GAM18205.1 - 0.051 13.2 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 GAM18205.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 GAM18205.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM18205.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF3045 PF11243.3 GAM18205.1 - 0.089 13.0 0.0 0.28 11.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3045) KNTase_C PF07827.6 GAM18205.1 - 0.095 12.4 0.0 6.2 6.5 0.0 2.3 1 1 1 2 2 2 0 KNTase C-terminal domain AAA_22 PF13401.1 GAM18205.1 - 0.099 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AlaDh_PNT_C PF01262.16 GAM18208.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Nuc-transf PF10127.4 GAM18210.1 - 3.6e-38 131.3 0.2 2.4e-25 89.3 0.1 2.3 2 1 0 2 2 2 2 Predicted nucleotidyltransferase Lep_receptor_Ig PF06328.6 GAM18211.1 - 0.057 13.2 0.4 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Ig-like C2-type domain Kelch_6 PF13964.1 GAM18213.1 - 8.8e-12 44.6 7.0 7.1e-05 22.8 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM18213.1 - 1e-07 31.8 0.3 0.0014 18.7 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM18213.1 - 5.9e-06 25.9 10.3 0.00017 21.2 0.0 4.7 4 2 1 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM18213.1 - 2e-05 24.4 1.9 0.056 13.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 GAM18213.1 - 0.00014 21.3 13.1 0.00036 20.0 0.1 3.9 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAM18213.1 - 0.015 15.0 1.4 13 5.7 0.0 3.9 4 0 0 4 4 4 0 Kelch motif Med7 PF05983.6 GAM18214.1 - 6.8e-53 178.7 4.9 1.9e-52 177.3 3.4 1.8 1 0 0 1 1 1 1 MED7 protein DUF842 PF05811.8 GAM18214.1 - 0.0068 15.8 0.2 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF3439 PF11921.3 GAM18214.1 - 0.013 15.2 18.0 0.34 10.6 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_L10 PF00466.15 GAM18214.1 - 0.033 14.1 1.4 0.093 12.6 0.9 1.8 1 0 0 1 1 1 0 Ribosomal protein L10 DUF1451 PF07295.6 GAM18214.1 - 0.067 12.9 0.7 0.13 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Mucin PF01456.12 GAM18214.1 - 0.31 10.7 32.3 0.47 10.2 6.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 GAM18214.1 - 0.48 8.3 25.3 0.84 7.5 6.5 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 SpoIIIAH PF12685.2 GAM18214.1 - 0.7 9.3 8.6 0.17 11.3 0.7 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Ctr PF04145.10 GAM18214.1 - 4.7 7.2 5.1 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Ctr copper transporter family PPTA PF01239.17 GAM18215.1 - 3.9e-39 130.3 17.7 2.4e-08 32.9 0.1 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4373 PF14297.1 GAM18215.1 - 0.13 12.5 1.5 0.43 10.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4373) Abhydrolase_6 PF12697.2 GAM18216.1 - 5.9e-16 59.0 0.0 7.4e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM18216.1 - 1.5e-15 57.2 0.1 1.6e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM18216.1 - 0.03 13.8 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM18216.1 - 0.04 13.5 0.3 0.096 12.2 0.1 1.7 1 1 1 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 GAM18216.1 - 0.081 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF1786 PF08735.5 GAM18216.1 - 0.15 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Cse1 PF08506.5 GAM18217.1 - 7.5e-111 370.2 6.1 1.7e-110 369.1 4.2 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 GAM18217.1 - 5.9e-89 298.3 3.1 5.9e-89 298.3 2.1 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 GAM18217.1 - 4.7e-13 48.8 0.8 1.6e-11 43.9 0.3 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 GAM18217.1 - 0.0093 15.8 0.1 0.0093 15.8 0.1 4.8 5 1 0 5 5 5 2 Exportin 1-like protein DEAD PF00270.24 GAM18218.1 - 1e-42 145.5 0.3 1.4e-42 145.0 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM18218.1 - 1.3e-24 85.8 0.1 2.6e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM18218.1 - 0.00029 20.7 0.0 0.00066 19.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAM18218.1 - 0.0012 17.6 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain RINT1_TIP1 PF04437.8 GAM18218.1 - 0.028 12.9 0.2 0.043 12.3 0.2 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family UPF0227 PF05728.7 GAM18218.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) HlyIII PF03006.15 GAM18221.1 - 4.5e-31 107.9 17.0 5.9e-31 107.6 11.8 1.2 1 0 0 1 1 1 1 Haemolysin-III related UAA PF08449.6 GAM18222.1 - 3.2e-81 272.5 20.4 4.3e-81 272.1 14.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM18222.1 - 5.5e-07 29.6 24.3 0.00026 21.0 5.5 3.2 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 GAM18222.1 - 0.00051 19.7 8.7 0.00051 19.7 6.0 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 GAM18222.1 - 0.0048 17.0 1.4 0.0048 17.0 1.0 3.1 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF979 PF06166.7 GAM18222.1 - 0.007 15.3 0.5 0.007 15.3 0.4 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF979) Viral_Beta_CD PF04530.7 GAM18222.1 - 0.87 9.7 3.6 0.92 9.6 0.1 2.7 2 1 1 3 3 3 0 Viral Beta C/D like family Reprolysin_2 PF13574.1 GAM18224.1 - 0.036 14.1 0.1 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3244 PF11589.3 GAM18225.1 - 2.6e-07 30.2 0.0 2 8.1 0.0 5.3 5 0 0 5 5 5 3 Domain of unknown function (DUF3244) DUF2012 PF09430.5 GAM18225.1 - 3.9e-05 23.4 0.0 11 5.8 0.0 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF2012) Cna_B PF05738.8 GAM18225.1 - 0.00017 21.2 13.4 0.0079 15.9 1.0 8.4 7 2 1 8 8 8 3 Cna protein B-type domain DUF2141 PF09912.4 GAM18225.1 - 0.00034 20.2 1.4 1.6 8.4 0.0 5.2 5 0 0 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2141) Y_Y_Y PF07495.8 GAM18225.1 - 0.0017 18.0 2.5 2.8 7.7 0.2 4.6 4 0 0 4 4 4 1 Y_Y_Y domain Glyco_transf_8 PF01501.15 GAM18226.1 - 1.6e-21 76.7 1.7 2.1e-21 76.3 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 GAM18226.1 - 0.00019 20.8 0.4 0.00031 20.1 0.1 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative Vel1p PF10339.4 GAM18226.1 - 0.035 13.2 0.5 0.1 11.7 0.1 1.8 2 0 0 2 2 2 0 Yeast-specific zinc responsive Pantoate_transf PF02548.10 GAM18227.1 - 1.9e-111 371.3 3.3 4.4e-111 370.1 2.0 1.8 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.6 GAM18227.1 - 1.3e-32 112.4 0.9 3e-32 111.2 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 GAM18227.1 - 1.9e-29 102.0 2.0 3e-29 101.3 0.1 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAM18227.1 - 4.2e-06 26.5 0.4 4.2e-06 26.5 0.3 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PEP_mutase PF13714.1 GAM18227.1 - 3.3e-05 23.2 0.4 0.00012 21.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Peptidase_U32 PF01136.14 GAM18227.1 - 0.044 12.7 0.0 0.34 9.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase family U32 3HCDH_N PF02737.13 GAM18227.1 - 0.1 12.2 0.0 0.1 12.2 0.0 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HTH_6 PF01418.12 GAM18227.1 - 0.11 12.2 4.6 0.38 10.5 3.2 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family RhoGEF PF00621.15 GAM18228.1 - 5.2e-49 166.5 1.9 9.1e-49 165.7 1.3 1.4 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAM18228.1 - 6.9e-21 73.9 10.5 1.6e-20 72.7 7.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAM18228.1 - 1.2e-09 38.2 0.5 3.5e-09 36.8 0.3 1.8 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 GAM18228.1 - 0.078 12.8 0.2 12 5.8 0.1 2.6 2 0 0 2 2 2 0 PH domain Ribonuclease_3 PF00636.21 GAM18228.1 - 0.093 13.1 1.3 0.26 11.7 0.0 2.4 2 1 0 2 2 2 0 Ribonuclease III domain Cna_B PF05738.8 GAM18229.1 - 2.9e-09 36.5 19.7 0.00026 20.6 0.1 6.4 6 3 2 8 8 8 2 Cna protein B-type domain DUF3244 PF11589.3 GAM18229.1 - 2.4e-08 33.6 1.1 0.033 13.8 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3244) Y_Y_Y PF07495.8 GAM18229.1 - 8.2e-06 25.4 1.2 0.19 11.4 0.0 4.3 4 1 0 4 4 4 2 Y_Y_Y domain DUF2012 PF09430.5 GAM18229.1 - 9.2e-06 25.5 0.0 0.23 11.3 0.0 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF2012) DoxA PF07680.6 GAM18229.1 - 0.00025 20.6 0.0 1.8 8.2 0.0 3.2 3 0 0 3 3 3 2 TQO small subunit DoxA Interfer-bind PF09294.5 GAM18229.1 - 0.00067 19.6 0.5 8.4 6.4 0.0 5.1 4 3 1 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III CarboxypepD_reg PF13620.1 GAM18229.1 - 0.0013 18.7 12.4 0.86 9.7 0.0 6.2 5 3 2 7 7 7 2 Carboxypeptidase regulatory-like domain DUF2141 PF09912.4 GAM18229.1 - 0.0061 16.2 0.0 11 5.6 0.0 4.1 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2141) Exo_endo_phos PF03372.18 GAM18230.1 - 9.7e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ODV-E18 PF10717.4 GAM18230.1 - 0.45 9.9 5.2 0.58 9.6 0.0 3.1 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Tim17 PF02466.14 GAM18231.1 - 3.7e-07 30.2 0.8 5.5e-07 29.6 0.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.1 GAM18231.1 - 0.013 14.9 1.6 1.3 8.5 0.4 2.5 2 1 0 2 2 2 0 YMGG-like Gly-zipper DUF1275 PF06912.6 GAM18231.1 - 0.055 12.6 0.5 0.7 9.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) Gly-zipper_Omp PF13488.1 GAM18231.1 - 0.6 9.7 5.7 4.2 7.0 1.0 2.5 2 1 0 2 2 2 0 Glycine zipper Endosulfine PF04667.12 GAM18232.1 - 3.3e-06 26.9 0.0 4.4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region tRNA-synt_2d PF01409.15 GAM18233.1 - 3.6e-87 291.6 0.0 4.9e-87 291.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 GAM18233.1 - 2.7e-06 26.3 0.1 1.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 GAM18233.1 - 2.8e-05 23.7 0.0 6.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Arm PF00514.18 GAM18234.1 - 9.1e-27 91.9 10.7 1.7e-05 24.4 0.0 8.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM18234.1 - 1.1e-06 28.8 0.0 0.64 10.3 0.0 4.0 2 2 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 GAM18234.1 - 3.7e-06 27.2 0.0 0.97 10.0 0.0 4.9 3 2 2 5 5 5 2 HEAT-like repeat HEAT PF02985.17 GAM18234.1 - 7.6e-05 22.4 0.0 5.6 7.3 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Thiolase_N PF00108.18 GAM18235.1 - 4.2e-92 307.8 1.2 4.2e-92 307.8 0.8 1.8 2 1 1 3 3 3 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM18235.1 - 3.3e-44 149.2 0.6 5.7e-44 148.4 0.4 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM18235.1 - 0.00032 20.2 0.3 0.00085 18.8 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 GAM18235.1 - 0.0066 16.4 0.0 0.025 14.6 0.0 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAM18235.1 - 0.05 13.2 1.5 0.67 9.6 0.0 3.2 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PseudoU_synth_1 PF01416.15 GAM18236.1 - 1.4e-15 57.6 0.1 7.9e-06 26.2 0.0 4.1 3 1 0 3 3 3 2 tRNA pseudouridine synthase SprT-like PF10263.4 GAM18237.1 - 5.6e-15 55.3 0.2 1.3e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 SprT-like family Tubulin PF00091.20 GAM18238.1 - 2.1e-33 115.9 2.0 7.4e-33 114.1 1.4 1.8 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.3 GAM18238.1 - 5.5e-23 80.8 0.0 1.6e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.1 GAM18238.1 - 0.0099 14.8 1.8 0.64 8.9 0.1 2.9 1 1 1 2 2 2 1 Tubulin like Sugar-bind PF04198.8 GAM18238.1 - 0.016 14.1 0.4 0.051 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative sugar-binding domain TP_methylase PF00590.15 GAM18238.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribonucleas_3_3 PF14622.1 GAM18239.1 - 4.2e-37 126.9 0.2 5.5e-18 65.1 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAM18239.1 - 3.3e-36 124.1 0.1 7.9e-17 61.7 0.0 3.2 2 1 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.20 GAM18239.1 - 1.1e-09 38.6 0.3 2.4e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 GAM18239.1 - 1.9e-05 24.8 0.3 5.8e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 Methyltransf_11 PF08241.7 GAM18239.1 - 0.056 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain F-box PF00646.28 GAM18240.1 - 0.99 9.1 4.3 0.44 10.2 0.2 2.5 3 0 0 3 3 3 0 F-box domain GCV_T PF01571.16 GAM18241.1 - 4e-67 225.6 0.1 5.2e-67 225.3 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAM18241.1 - 1.3e-22 79.6 0.1 2.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 GAM18241.1 - 2.5e-06 27.4 0.0 1.1e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.4 GAM18241.1 - 0.027 14.4 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus Pirin PF02678.11 GAM18243.1 - 1.2e-30 105.5 0.1 1.8e-30 104.9 0.1 1.2 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 GAM18243.1 - 6.7e-09 35.7 0.0 7.3e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 GAM18243.1 - 9.2e-05 21.8 0.4 0.017 14.6 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Ank_2 PF12796.2 GAM18244.1 - 1.4e-29 102.2 6.9 2.6e-09 37.2 0.1 6.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM18244.1 - 1e-22 80.0 12.6 0.0033 17.8 0.0 9.1 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18244.1 - 1.6e-19 68.0 5.6 5.1 7.6 0.0 11.5 7 3 4 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 GAM18244.1 - 9.4e-18 63.8 8.2 2 8.8 0.0 11.1 4 2 7 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM18244.1 - 1.3e-13 50.0 4.8 5.2 7.0 0.0 9.9 10 0 0 10 10 10 3 Ankyrin repeat DUF3447 PF11929.3 GAM18244.1 - 0.00047 19.9 9.9 0.0036 17.0 0.0 5.1 5 1 1 6 6 6 1 Domain of unknown function (DUF3447) PhoPQ_related PF10142.4 GAM18245.1 - 6.3e-125 416.4 1.7 7.4e-125 416.2 1.2 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 GAM18245.1 - 0.0038 17.0 0.0 0.0078 15.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L25p PF01386.14 GAM18246.1 - 8e-05 22.6 0.1 0.00016 21.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L25p family AAA_22 PF13401.1 GAM18247.1 - 7.1e-12 45.5 0.0 2.3e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM18247.1 - 6.2e-10 39.3 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM18247.1 - 6e-07 29.6 0.0 1.5e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.6 GAM18247.1 - 1.7e-06 27.6 0.2 8e-05 22.2 0.0 3.0 2 1 1 3 3 3 1 CDC6, C terminal DUF2075 PF09848.4 GAM18247.1 - 0.00059 18.9 0.0 0.00089 18.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 GAM18247.1 - 0.00071 18.5 1.0 0.0011 17.8 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain DEAD PF00270.24 GAM18247.1 - 0.0013 18.2 0.5 0.4 10.1 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase IstB_IS21 PF01695.12 GAM18247.1 - 0.0022 17.4 0.0 0.038 13.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAM18247.1 - 0.004 17.0 0.7 0.015 15.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain GvpD PF07088.6 GAM18247.1 - 0.0059 14.9 0.0 0.0096 14.2 0.0 1.3 1 0 0 1 1 1 1 GvpD gas vesicle protein Cro PF09048.5 GAM18247.1 - 0.057 13.0 0.2 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Cro AAA_32 PF13654.1 GAM18247.1 - 0.06 12.0 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM18247.1 - 0.072 12.8 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GATA PF00320.22 GAM18248.1 - 2e-12 46.2 0.5 3.3e-12 45.5 0.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Calpain_III PF01067.17 GAM18249.1 - 6.1e-49 165.4 7.2 1.3e-22 80.0 0.0 4.8 4 1 0 5 5 5 4 Calpain large subunit, domain III DoxA PF07680.6 GAM18249.1 - 0.052 13.1 0.0 4.3 6.9 0.0 3.3 2 1 1 3 3 3 0 TQO small subunit DoxA Gag_p12 PF01141.13 GAM18249.1 - 9.4 6.4 12.3 0.13 12.3 3.2 1.9 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 DUF1296 PF06972.6 GAM18251.1 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1296) UBA PF00627.26 GAM18251.1 - 0.0012 18.5 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ADP_ribosyl_GH PF03747.9 GAM18252.1 - 1.4e-44 153.0 0.0 1.8e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF4535 PF15054.1 GAM18252.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Med14 PF08638.6 GAM18253.1 - 2.6e-32 111.6 2.6 6.4e-21 74.4 0.0 3.0 2 0 0 2 2 2 2 Mediator complex subunit MED14 Histone PF00125.19 GAM18254.1 - 3.5e-30 103.9 0.7 5.4e-30 103.3 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM18254.1 - 1.3e-05 25.2 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 GAM18254.1 - 0.02 14.1 1.0 0.024 13.9 0.7 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 GAM18254.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Epimerase PF01370.16 GAM18255.1 - 1.8e-19 70.1 0.4 3e-19 69.4 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM18255.1 - 1.3e-16 60.3 0.2 1.9e-15 56.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 GAM18255.1 - 9.2e-16 57.3 0.0 1.2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM18255.1 - 1.5e-09 38.1 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM18255.1 - 1.9e-07 30.5 0.1 3.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 GAM18255.1 - 0.0009 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 GAM18255.1 - 0.0017 18.0 0.1 0.037 13.6 0.0 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 GAM18255.1 - 0.0017 17.3 0.4 0.0046 15.8 0.3 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Ins_allergen_rp PF06757.8 GAM18255.1 - 0.0017 17.8 0.2 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Insect allergen related repeat, nitrile-specifier detoxification adh_short PF00106.20 GAM18255.1 - 0.013 15.4 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase DUF2209 PF09974.4 GAM18255.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) DUF1769 PF08588.5 GAM18255.1 - 3 7.8 4.8 35 4.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1769) Pkinase PF00069.20 GAM18256.1 - 1.5e-64 217.6 0.2 1.5e-64 217.6 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18256.1 - 5.1e-43 147.0 0.0 5.1e-43 147.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM18256.1 - 3.7e-05 22.8 0.0 0.00012 21.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAM18256.1 - 0.024 14.3 0.0 0.068 12.8 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family GAGA_bind PF06217.7 GAM18256.1 - 0.028 14.3 2.6 0.042 13.8 1.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Seadorna_VP7 PF07387.6 GAM18256.1 - 0.09 11.5 0.1 0.09 11.5 0.0 2.2 3 0 0 3 3 3 0 Seadornavirus VP7 MRP-S33 PF08293.6 GAM18256.1 - 0.36 10.8 3.7 2.7 8.0 0.8 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 OmpH PF03938.9 GAM18256.1 - 5.6 6.8 11.1 10 6.0 7.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) XhlA PF10779.4 GAM18256.1 - 6.4 6.7 8.6 32 4.5 5.9 2.2 1 1 0 1 1 1 0 Haemolysin XhlA Ribosomal_L35Ae PF01247.13 GAM18257.1 - 2.9e-35 119.8 0.3 3.3e-35 119.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 GAM18257.1 - 0.056 13.3 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain GRAM PF02893.15 GAM18259.1 - 0.059 12.8 0.4 0.25 10.8 0.2 2.1 1 1 0 1 1 1 0 GRAM domain RPEL PF02755.10 GAM18260.1 - 2.5e-07 29.7 30.8 0.00018 20.7 0.4 8.3 9 0 0 9 9 9 6 RPEL repeat DUF1395 PF07160.7 GAM18261.1 - 8.3e-06 25.4 8.3 8.4e-06 25.4 4.8 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1395) DUF3161 PF11362.3 GAM18261.1 - 0.013 15.3 2.4 0.015 15.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3161) Pathogen_betaC1 PF09593.5 GAM18261.1 - 0.062 13.0 0.4 0.28 10.9 0.1 2.0 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PYST-C1 PF09690.5 GAM18261.1 - 0.21 11.2 9.0 0.55 9.8 6.2 1.7 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) AP-5_subunit_s1 PF15001.1 GAM18264.1 - 1.5e-23 83.7 3.5 2.5e-18 66.6 0.2 2.5 2 1 0 2 2 2 2 AP-5 complex subunit sigma-1 Clat_adaptor_s PF01217.15 GAM18264.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2183 PF09949.4 GAM18264.1 - 0.032 14.1 0.4 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) CBM49 PF09478.5 GAM18265.1 - 3.3e-20 71.9 1.4 4.4e-20 71.5 0.9 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Snurportin1 PF11538.3 GAM18266.1 - 0.0045 16.7 3.0 0.0045 16.7 2.1 2.1 2 0 0 2 2 2 1 Snurportin1 Dicty_REP PF05086.7 GAM18266.1 - 0.012 13.4 6.5 0.016 13.0 4.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pox_A_type_inc PF04508.7 GAM18266.1 - 0.027 14.2 1.8 0.078 12.8 1.2 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Peptidase_S9 PF00326.16 GAM18267.1 - 7.6e-09 35.0 0.1 1.4e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM18267.1 - 8.5e-08 32.0 0.1 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM18267.1 - 0.061 13.1 0.5 0.31 10.8 0.4 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family S_layer_C PF05124.7 GAM18267.1 - 0.26 10.8 0.0 0.44 10.1 0.0 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region CDC45 PF02724.9 GAM18269.1 - 0.21 9.5 6.8 0.23 9.4 4.2 1.4 2 0 0 2 2 2 0 CDC45-like protein RRN3 PF05327.6 GAM18269.1 - 0.58 8.1 7.1 1 7.4 4.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ABC2_membrane_3 PF12698.2 GAM18270.1 - 1.3 7.9 13.9 1.9 7.4 3.4 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Dicty_REP PF05086.7 GAM18270.1 - 6.5 4.3 34.4 0.22 9.2 4.6 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF4543 PF15076.1 GAM18271.1 - 0.11 12.5 1.3 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4543) Trypan_glycop_C PF10659.4 GAM18272.1 - 3.6 7.9 18.9 5.2 7.4 13.1 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain COX7C PF02935.11 GAM18272.1 - 7.5 6.4 6.4 17 5.2 4.1 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Senescence_reg PF04520.8 GAM18272.1 - 8.7 6.8 8.0 10 6.6 5.5 1.2 1 0 0 1 1 1 0 Senescence regulator PAP1 PF08601.5 GAM18272.1 - 8.7 5.9 21.9 9.6 5.7 15.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Rifin_STEVOR PF02009.11 GAM18272.1 - 9.9 5.7 12.2 12 5.4 8.5 1.0 1 0 0 1 1 1 0 Rifin/stevor family RAG1 PF12940.2 GAM18275.1 - 0.0004 18.8 0.1 0.00051 18.5 0.0 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) Nup35_RRM_2 PF14605.1 GAM18276.1 - 0.039 13.7 0.2 3.1 7.6 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Pox_F17 PF04767.7 GAM18276.1 - 0.9 9.8 6.6 1.8 8.8 4.1 1.7 1 1 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Pkinase PF00069.20 GAM18277.1 - 4.6e-73 245.5 0.0 6.5e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18277.1 - 1.3e-34 119.4 0.1 2.4e-34 118.5 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM18277.1 - 1.1e-05 24.5 0.1 0.00018 20.5 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAM18277.1 - 0.0076 15.3 0.5 0.013 14.5 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM18277.1 - 0.053 13.2 0.0 2.7 7.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Inositol_P PF00459.20 GAM18278.1 - 1.8e-68 230.8 0.0 2.1e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PI3Ka PF00613.15 GAM18279.1 - 2.9e-53 179.7 1.2 6.4e-53 178.6 0.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM18279.1 - 2.8e-46 157.8 0.0 8.7e-46 156.2 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM18279.1 - 3.7e-21 75.4 0.0 8.1e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 GAM18279.1 - 5.4e-13 48.8 3.4 1.4e-09 37.8 0.1 3.5 2 1 1 3 3 3 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.1 GAM18279.1 - 0.023 13.7 0.0 0.71 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Histone PF00125.19 GAM18280.1 - 4.1e-17 62.0 0.3 6.5e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM18280.1 - 0.0086 16.2 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 GAM18280.1 - 0.0095 15.9 0.4 0.0095 15.9 0.3 2.2 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2890 PF11081.3 GAM18280.1 - 0.021 14.8 0.7 0.031 14.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RPA_C PF08784.6 GAM18280.1 - 0.23 11.9 1.5 3.3 8.1 1.0 2.2 1 1 0 1 1 1 0 Replication protein A C terminal FokI_C PF02980.11 GAM18280.1 - 0.54 9.8 4.9 1.3 8.7 3.0 1.8 1 1 1 2 2 2 0 Restriction endonuclease FokI, catalytic domain eIF-4B PF06273.6 GAM18280.1 - 2.5 6.7 6.6 3.6 6.2 4.6 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PIP5K PF01504.13 GAM18281.1 - 1.6e-63 214.1 9.1 2.3e-63 213.6 5.7 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_CAR PF05462.6 GAM18281.1 - 1.4e-16 60.3 9.1 2.7e-16 59.3 6.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 GAM18281.1 - 4.8e-10 39.0 4.6 8.9e-10 38.1 3.2 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.12 GAM18281.1 - 8.8e-09 34.5 11.0 3.5e-08 32.6 7.6 1.8 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.19 GAM18281.1 - 8.3e-08 31.6 7.7 1.6e-07 30.6 5.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.4 GAM18281.1 - 0.0019 17.4 6.8 0.0029 16.7 4.7 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx RED_N PF07808.8 GAM18281.1 - 0.0031 16.7 8.3 0.0072 15.5 5.7 1.5 1 0 0 1 1 1 1 RED-like protein N-terminal region DUF2036 PF09724.4 GAM18282.1 - 3.5e-67 226.8 0.0 4.2e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) FBA PF04300.8 GAM18282.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 F-box associated region Dirigent PF03018.9 GAM18282.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Dirigent-like protein Peptidase_C1 PF00112.18 GAM18283.1 - 3.1e-48 164.5 8.9 4e-48 164.1 6.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 GAM18283.1 - 0.0016 17.0 0.9 0.063 11.7 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.1 GAM18283.1 - 0.015 15.6 2.4 0.039 14.3 1.6 1.9 1 1 0 1 1 1 0 Peptidase_C39 like family DUF4106 PF13388.1 GAM18283.1 - 9.6 5.0 9.3 14 4.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Inhibitor_I29 PF08246.7 GAM18284.1 - 0.05 13.8 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Pentapeptide_4 PF13599.1 GAM18285.1 - 4.6e-16 58.3 37.3 1.8e-08 34.0 8.7 3.4 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 GAM18285.1 - 1.7e-10 40.6 19.3 2.1e-07 30.7 6.4 4.0 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 GAM18285.1 - 5.1e-08 31.9 14.8 0.00048 19.3 1.7 4.1 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) zf-RING_2 PF13639.1 GAM18285.1 - 0.065 13.0 20.4 0.028 14.2 9.6 2.7 2 0 0 2 2 2 0 Ring finger domain DUF605 PF04652.11 GAM18285.1 - 0.85 8.9 24.2 1.2 8.4 16.8 1.3 1 0 0 1 1 1 0 Vta1 like DUF3666 PF12408.3 GAM18285.1 - 4.6 6.4 9.5 15 4.7 0.1 3.5 2 1 1 3 3 3 0 Ribose-5-phosphate isomerase DUF4380 PF14315.1 GAM18286.1 - 9.9e-58 195.4 0.1 1.2e-57 195.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) dsDNA_bind PF01984.15 GAM18287.1 - 1.1e-28 99.2 11.3 1.3e-28 99.0 7.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Fes1 PF08609.5 GAM18287.1 - 0.13 12.7 0.4 0.17 12.3 0.3 1.2 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Aconitase PF00330.15 GAM18289.1 - 8.8e-140 466.2 0.0 1.1e-139 465.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM18289.1 - 8.8e-38 129.3 0.0 1.6e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain NTS_2 PF15448.1 GAM18289.1 - 0.16 12.3 0.0 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein CH PF00307.26 GAM18290.1 - 1.2e-15 57.4 0.1 2.9e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM18290.1 - 4.3e-11 42.3 0.1 1e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 CAMSAP CH domain FYVE PF01363.16 GAM18291.1 - 4.1e-18 65.0 8.3 8.7e-18 63.9 5.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_C PF02752.17 GAM18291.1 - 5.1e-08 33.1 6.2 0.02 14.9 0.0 4.0 2 2 1 3 3 3 3 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 GAM18291.1 - 8.6e-05 22.3 5.2 0.0014 18.4 0.0 3.3 5 0 0 5 5 5 1 Arrestin (or S-antigen), N-terminal domain TMEM171 PF15471.1 GAM18291.1 - 0.001 17.9 1.7 0.0018 17.1 1.2 1.4 1 0 0 1 1 1 1 Transmembrane protein family 171 zf-RING_5 PF14634.1 GAM18291.1 - 0.2 11.3 10.5 0.46 10.2 7.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain IBR PF01485.16 GAM18291.1 - 0.34 10.8 6.4 0.19 11.6 2.3 2.1 2 0 0 2 2 2 0 IBR domain zf-C3HC4_2 PF13923.1 GAM18291.1 - 3.3 7.8 8.5 19 5.3 6.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM18291.1 - 4.4 7.2 11.6 40 4.1 7.9 2.4 1 1 1 2 2 2 0 Ring finger domain eIF-5a PF01287.15 GAM18292.1 - 1.4e-25 89.0 0.0 2.1e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 GAM18292.1 - 0.00048 19.9 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 GAM18292.1 - 0.11 12.2 0.3 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 KOW motif Glyco_transf_20 PF00982.16 GAM18293.1 - 4.5e-141 470.5 0.0 7.2e-141 469.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM18293.1 - 4.9e-62 208.9 0.0 7.1e-62 208.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 GAM18293.1 - 0.00033 20.3 0.0 0.31 10.5 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.1 GAM18294.1 - 2.4e-10 40.0 13.0 4.6e-10 39.1 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM18294.1 - 9e-10 38.0 11.0 1.5e-09 37.3 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM18294.1 - 2.9e-08 33.6 13.8 5.3e-08 32.7 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM18294.1 - 4.8e-08 32.5 14.2 1e-07 31.4 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM18294.1 - 8.4e-08 31.8 11.3 1.8e-07 30.7 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 GAM18294.1 - 2.4e-05 24.3 11.2 8.3e-05 22.6 7.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger TerY-C PF15616.1 GAM18294.1 - 3.9e-05 23.6 4.4 3.9e-05 23.6 3.1 2.3 2 0 0 2 2 2 1 TerY-C metal binding domain zf-RING_UBOX PF13445.1 GAM18294.1 - 0.0002 21.0 5.5 0.00051 19.7 1.9 2.8 1 1 1 2 2 2 1 RING-type zinc-finger Med15 PF09606.5 GAM18294.1 - 0.0044 15.3 11.6 0.0046 15.2 8.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Folliculin PF11704.3 GAM18294.1 - 0.014 15.0 4.8 0.014 15.0 3.3 1.6 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport zf-C3HC4_4 PF15227.1 GAM18294.1 - 0.014 15.2 11.6 0.075 12.9 8.0 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 GAM18294.1 - 0.034 13.9 5.3 0.092 12.5 3.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 GAM18294.1 - 0.041 13.6 7.0 0.19 11.5 4.9 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 GAM18294.1 - 0.056 12.9 6.3 0.14 11.6 4.4 1.7 1 0 0 1 1 1 0 P-11 zinc finger Peptidase_S15 PF02129.13 GAM18294.1 - 0.088 12.2 1.6 0.13 11.6 1.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BAF1_ABF1 PF04684.8 GAM18294.1 - 0.34 9.7 18.3 0.48 9.2 12.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ctr PF04145.10 GAM18294.1 - 1.1 9.2 3.0 2.4 8.2 2.1 1.5 1 0 0 1 1 1 0 Ctr copper transporter family Activator_LAG-3 PF11498.3 GAM18294.1 - 1.2 7.8 21.6 1.6 7.4 15.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.3 GAM18294.1 - 2.1 7.4 13.0 3.1 6.9 9.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ELO PF01151.13 GAM18295.1 - 1.5e-53 181.6 23.2 1.9e-53 181.3 16.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FH2 PF02181.18 GAM18296.1 - 2.6e-83 279.9 2.2 3.5e-83 279.5 1.5 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain zf-C4H2 PF10146.4 GAM18296.1 - 0.035 14.1 0.9 0.089 12.7 0.6 1.7 1 1 0 1 1 1 0 Zinc finger-containing protein Peptidase_M75 PF09375.5 GAM18296.1 - 0.088 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Imelysin Sec61_beta PF03911.11 GAM18297.1 - 2.2e-19 68.9 0.2 2.5e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Sec61beta family Thioredoxin PF00085.15 GAM18298.1 - 2.2e-42 142.9 11.1 2.7e-25 88.0 0.5 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 GAM18298.1 - 8.7e-35 120.1 6.6 2.3e-32 112.3 1.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.12 GAM18298.1 - 2.5e-12 46.2 3.7 4.9e-12 45.3 0.3 2.5 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.1 GAM18298.1 - 1.1e-10 41.3 1.4 0.00033 20.6 0.1 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM18298.1 - 9.5e-10 38.6 8.5 0.00076 19.6 2.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM18298.1 - 2.7e-09 37.0 4.1 0.001 19.1 0.0 5.3 3 3 2 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.16 GAM18298.1 - 0.0005 19.7 0.3 0.3 10.7 0.1 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.1 GAM18298.1 - 0.76 9.7 5.0 14 5.6 0.0 3.9 4 0 0 4 4 4 0 Thioredoxin GCD14 PF08704.5 GAM18299.1 - 4.4e-98 327.6 0.0 5.4e-98 327.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 GAM18299.1 - 2.2e-07 30.6 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM18299.1 - 2.2e-06 28.1 0.0 4.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM18299.1 - 9.1e-06 25.6 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 GAM18299.1 - 0.00011 21.3 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 GAM18299.1 - 0.00043 21.0 0.0 0.00082 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.8 GAM18299.1 - 0.0068 15.5 0.4 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Gcd10p family MTS PF05175.9 GAM18299.1 - 0.01 15.2 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 GAM18299.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 GAM18299.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Spc7 PF08317.6 GAM18300.1 - 3.4e-05 22.6 23.7 3.4e-05 22.6 16.4 4.1 2 1 2 4 4 4 1 Spc7 kinetochore protein GAS PF13851.1 GAM18300.1 - 0.0041 16.3 10.7 0.0041 16.3 7.4 5.1 3 1 2 5 5 5 2 Growth-arrest specific micro-tubule binding IncA PF04156.9 GAM18300.1 - 0.021 14.4 72.8 0.085 12.4 22.1 4.7 2 1 3 5 5 5 0 IncA protein DDE_Tnp_IS66_C PF13817.1 GAM18300.1 - 0.095 12.7 0.0 0.49 10.4 0.0 2.3 1 0 0 1 1 1 0 IS66 C-terminal element ATG16 PF08614.6 GAM18300.1 - 0.64 9.8 72.5 0.038 13.8 10.7 4.5 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) BRCT PF00533.21 GAM18303.1 - 0.0032 17.5 0.5 0.081 13.0 0.0 2.8 2 2 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Dicty_REP PF05086.7 GAM18303.1 - 0.56 7.8 13.4 0.88 7.2 9.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Omega-toxin PF06357.6 GAM18303.1 - 6 6.5 5.5 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Omega-atracotoxin Ank_2 PF12796.2 GAM18304.1 - 3.4e-14 52.9 2.4 3.4e-06 27.3 0.0 5.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM18304.1 - 8.9e-09 35.6 10.6 0.009 16.5 0.0 8.2 7 2 2 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18304.1 - 6.5e-08 32.0 5.3 0.56 10.6 0.0 7.9 7 1 1 8 8 8 1 Ankyrin repeat Ank_5 PF13857.1 GAM18304.1 - 1.8e-06 27.9 8.1 0.13 12.5 0.0 6.7 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM18304.1 - 7.5e-05 22.3 8.9 0.32 10.9 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat DnaG_DnaB_bind PF08278.6 GAM18304.1 - 0.022 14.9 0.3 2.3 8.4 0.0 3.2 3 0 0 3 3 3 0 DNA primase DnaG DnaB-binding FAR1 PF03101.10 GAM18306.1 - 0.13 12.7 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 FAR1 DNA-binding domain Hamartin PF04388.7 GAM18308.1 - 0.68 8.5 5.6 0.73 8.4 3.9 1.1 1 0 0 1 1 1 0 Hamartin protein TMEM154 PF15102.1 GAM18308.1 - 7.4 6.2 8.6 0.99 9.1 3.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family THF_DHG_CYH_C PF02882.14 GAM18309.1 - 6.3e-71 236.6 5.2 6.3e-71 236.6 3.6 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAM18309.1 - 8e-40 135.5 1.4 1.4e-39 134.7 1.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.10 GAM18309.1 - 0.0043 15.8 0.7 0.0069 15.1 0.5 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Xpo1 PF08389.7 GAM18310.1 - 3.6e-34 117.8 11.2 9.3e-34 116.4 2.2 4.4 5 2 0 5 5 5 2 Exportin 1-like protein TRAP-gamma PF07074.7 GAM18311.1 - 9.7e-27 93.5 8.7 1.1e-26 93.3 6.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3796 PF12676.2 GAM18311.1 - 1.2 9.3 8.4 0.34 11.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) TRM13 PF05206.9 GAM18312.1 - 2.7e-63 213.6 3.3 4.5e-63 212.9 2.3 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 GAM18312.1 - 2.2e-08 33.6 1.5 5.1e-08 32.4 1.0 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.3 GAM18312.1 - 1e-06 27.9 4.3 1e-06 27.9 3.0 2.4 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Vps5 PF09325.5 GAM18312.1 - 0.045 13.0 0.1 0.045 13.0 0.1 1.8 2 0 0 2 2 2 0 Vps5 C terminal like FNIP PF05725.7 GAM18313.1 - 8.3e-43 144.1 13.0 2.7e-13 49.6 0.9 5.2 4 1 0 5 5 5 4 FNIP Repeat Ank_2 PF12796.2 GAM18314.1 - 1e-09 38.6 5.8 2.2e-05 24.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM18314.1 - 9.7e-06 25.9 12.4 0.004 17.6 0.2 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18314.1 - 0.13 12.5 12.2 3.9 8.0 0.1 6.5 7 0 0 7 7 7 0 Ankyrin repeat Ank PF00023.25 GAM18314.1 - 0.49 10.3 8.1 38 4.3 0.1 5.3 5 0 0 5 5 5 0 Ankyrin repeat Sporozoite_P67 PF05642.6 GAM18317.1 - 0.0012 16.8 0.8 0.0014 16.6 0.5 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 GAM18317.1 - 0.0014 18.3 4.4 0.0018 17.9 3.1 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 GAM18317.1 - 0.0015 18.7 5.9 0.0022 18.1 4.1 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF4611 PF15387.1 GAM18317.1 - 0.0044 17.1 2.5 0.0062 16.6 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Myc_N PF01056.13 GAM18317.1 - 0.013 14.7 0.3 0.014 14.5 0.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 GAM18317.1 - 0.013 14.5 0.6 0.015 14.2 0.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1510 PF07423.6 GAM18317.1 - 0.023 14.0 0.3 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 GAM18317.1 - 0.043 13.4 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.5 GAM18317.1 - 0.33 9.9 6.1 0.41 9.6 4.2 1.0 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.6 GAM18317.1 - 0.43 10.3 3.9 0.59 9.9 2.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.7 GAM18317.1 - 0.63 9.7 4.6 0.82 9.3 3.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nop14 PF04147.7 GAM18317.1 - 1.1 7.0 9.4 1.4 6.7 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 GAM18317.1 - 1.4 8.3 10.0 2.1 7.8 7.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2890 PF11081.3 GAM18317.1 - 2.4 8.1 5.7 3.3 7.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 GAM18317.1 - 3.4 5.5 8.9 4.4 5.2 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 GAM18317.1 - 5.9 5.9 12.7 7.5 5.5 8.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CAP_N PF01213.14 GAM18318.1 - 3.5e-103 345.1 0.6 4.6e-103 344.7 0.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 GAM18318.1 - 1.7e-62 209.4 9.0 2.6e-62 208.8 6.3 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 GAM18318.1 - 2e-06 27.2 5.3 4.7e-06 25.9 3.7 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C Matrilin_ccoil PF10393.4 GAM18318.1 - 0.064 12.6 2.3 0.48 9.8 0.4 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DASH_Dam1 PF08653.5 GAM18318.1 - 0.66 9.7 2.9 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Ribosomal_60s PF00428.14 GAM18318.1 - 2.4 8.6 14.0 2.7 8.4 2.8 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein RhoGAP PF00620.22 GAM18319.1 - 7e-35 119.8 0.7 1.3e-33 115.7 0.1 3.0 2 1 1 3 3 3 1 RhoGAP domain RhoGEF PF00621.15 GAM18319.1 - 3.4e-33 115.0 0.4 1.1e-32 113.4 0.2 2.0 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM18319.1 - 7.2e-06 26.1 1.3 7.2e-06 26.1 0.9 3.7 4 1 0 4 4 4 1 PH domain CarboxypepD_reg PF13620.1 GAM18319.1 - 0.0014 18.6 0.1 0.0014 18.6 0.0 2.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain IQ PF00612.22 GAM18319.1 - 0.078 12.6 0.5 0.19 11.4 0.4 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif DEAD PF00270.24 GAM18320.1 - 9.2e-44 148.9 1.2 1.7e-43 148.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM18320.1 - 2.2e-22 78.7 0.1 9.9e-22 76.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM18320.1 - 8.1e-22 76.5 0.1 1.5e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Apc15p PF05841.6 GAM18320.1 - 6.7 7.4 13.2 1.5 9.5 2.0 2.7 2 0 0 2 2 2 0 Apc15p protein HAS-barrel PF09378.5 GAM18324.1 - 0.021 14.7 0.9 1.6 8.7 0.1 2.9 2 1 1 3 3 3 0 HAS barrel domain TatC PF00902.13 GAM18324.1 - 0.027 13.8 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) DUF4407 PF14362.1 GAM18324.1 - 0.031 13.2 1.1 0.051 12.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hormone_3 PF00159.13 GAM18324.1 - 0.076 13.0 0.1 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide Filament PF00038.16 GAM18324.1 - 0.17 11.3 9.6 0.73 9.2 2.4 2.1 2 0 0 2 2 2 0 Intermediate filament protein DDE_Tnp_IS240 PF13610.1 GAM18324.1 - 0.26 11.2 2.9 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 DDE domain IncA PF04156.9 GAM18324.1 - 4 6.9 5.7 23 4.5 0.7 2.5 2 1 0 2 2 2 0 IncA protein DUF148 PF02520.12 GAM18324.1 - 4.2 7.2 9.2 2.3 8.0 2.4 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 PRCC PF10253.4 GAM18324.1 - 5 7.7 15.6 0.059 14.0 3.0 2.3 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Racemase_4 PF13615.1 GAM18325.1 - 1.3e-28 99.2 0.8 3.4e-28 97.8 0.5 1.8 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 GAM18325.1 - 8.6e-27 93.1 0.0 2.3e-26 91.7 0.0 1.7 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Pkinase PF00069.20 GAM18326.1 - 1.9e-55 187.8 0.1 3.8e-55 186.8 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18326.1 - 1.7e-23 83.0 0.2 4.5e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase G-alpha PF00503.15 GAM18327.1 - 2.2e-107 359.1 5.4 2.7e-107 358.8 3.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM18327.1 - 4.1e-15 55.4 0.9 2.4e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 GAM18327.1 - 0.0092 16.4 0.0 7.5 7.0 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 GAM18327.1 - 0.041 13.8 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM18327.1 - 0.071 13.0 0.6 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 GAM18327.1 - 0.089 11.9 0.6 1.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF4089 PF13318.1 GAM18327.1 - 0.12 12.6 0.4 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) PIF1 PF05970.9 GAM18328.1 - 9.9e-60 202.3 2.5 5.4e-58 196.6 0.7 2.6 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 GAM18328.1 - 1.8e-13 50.4 0.0 7.1e-09 35.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain U-box PF04564.10 GAM18328.1 - 8.5e-12 44.8 1.0 5.7e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 U-box domain Viral_helicase1 PF01443.13 GAM18328.1 - 3.7e-06 26.6 0.3 0.013 15.0 0.0 3.3 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 GAM18328.1 - 6.4e-05 22.4 0.1 0.00072 19.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAM18328.1 - 6.8e-05 22.7 0.0 0.00032 20.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 GAM18328.1 - 0.00022 20.7 0.0 0.00052 19.5 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 GAM18328.1 - 0.00025 21.1 0.0 0.00082 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 GAM18328.1 - 0.0011 18.5 0.2 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 GAM18328.1 - 0.0014 18.3 0.3 0.039 13.6 0.1 2.5 2 0 0 2 2 2 1 NTPase FtsK_SpoIIIE PF01580.13 GAM18328.1 - 0.0016 17.9 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 GAM18328.1 - 0.0045 16.7 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 GAM18328.1 - 0.0047 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 GAM18328.1 - 0.0062 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain UvrD_C_2 PF13538.1 GAM18328.1 - 0.0071 16.4 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 GAM18328.1 - 0.0088 15.2 0.1 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 GAM18328.1 - 0.012 14.5 0.1 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 GAM18328.1 - 0.02 14.6 0.0 0.055 13.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAM18328.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 GAM18328.1 - 0.03 14.5 0.8 0.12 12.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 GAM18328.1 - 0.083 13.1 2.9 0.14 12.5 0.1 2.7 3 1 0 3 3 3 0 ABC transporter ArgK PF03308.11 GAM18328.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Sigma54_activat PF00158.21 GAM18328.1 - 0.12 11.8 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Abhydrolase_6 PF12697.2 GAM18329.1 - 6.4e-29 101.4 0.0 7.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM18329.1 - 5.7e-15 55.4 0.0 3.3e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM18329.1 - 4.6e-14 52.3 0.0 6.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM18329.1 - 2e-07 30.8 0.1 6.1e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAM18329.1 - 6.6e-05 22.3 0.1 0.0001 21.6 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 GAM18329.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 GAM18329.1 - 0.0055 16.9 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 GAM18329.1 - 0.006 16.2 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 GAM18329.1 - 0.023 13.8 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.6 GAM18329.1 - 0.035 12.8 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ndr PF03096.9 GAM18329.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_3 PF07859.8 GAM18329.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 GAM18329.1 - 0.14 11.4 0.0 3.2 6.9 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Nucleoporin2 PF04096.9 GAM18330.1 - 8.4e-43 145.5 0.0 1.6e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 GAM18330.1 - 0.0001 22.5 41.8 0.0001 22.5 29.0 9.8 3 2 5 8 8 8 3 Nucleoporin FG repeat region Nup96 PF12110.3 GAM18331.1 - 2.3e-65 220.5 2.6 2.3e-65 220.5 1.8 2.1 3 0 0 3 3 3 1 Nuclear protein 96 PARP_reg PF02877.9 GAM18331.1 - 0.03 13.9 1.7 0.059 13.0 0.1 2.3 2 1 1 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain DUF445 PF04286.7 GAM18331.1 - 0.95 8.9 5.0 0.83 9.1 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF445) NT-C2 PF10358.4 GAM18332.1 - 3.8e-09 36.1 0.1 7.1e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 GAM18332.1 - 6e-09 35.7 4.8 6e-09 35.7 3.3 2.3 3 0 0 3 3 3 1 DIL domain Mito_carr PF00153.22 GAM18333.1 - 1.4e-10 40.7 0.5 0.00042 19.9 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein T_cell_tran_alt PF15128.1 GAM18333.1 - 0.17 11.3 1.0 3.2 7.2 0.0 2.7 3 0 0 3 3 3 0 T-cell leukemia translocation-altered Ribosomal_S25 PF03297.10 GAM18334.1 - 3.9e-36 123.2 1.1 4.4e-36 123.1 0.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.15 GAM18334.1 - 0.092 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TATR PF03430.8 GAM18334.1 - 0.17 10.4 0.9 0.2 10.2 0.7 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator RabGAP-TBC PF00566.13 GAM18336.1 - 1.5e-09 37.6 5.0 1.5e-09 37.6 3.4 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Dna2 PF08696.6 GAM18336.1 - 0.025 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 Rhodanese PF00581.15 GAM18336.1 - 0.033 14.5 0.0 0.093 13.0 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain BRCT PF00533.21 GAM18337.1 - 8.8e-06 25.7 0.0 3.6e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RRM_5 PF13893.1 GAM18337.1 - 1.3e-05 24.8 0.1 3.5e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTCB-BRCT PF12738.2 GAM18337.1 - 0.0014 18.4 0.1 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain RRM_1 PF00076.17 GAM18337.1 - 0.0075 15.8 0.1 0.023 14.3 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM18337.1 - 0.016 15.1 0.2 0.059 13.3 0.1 2.0 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nop53 PF07767.6 GAM18338.1 - 0.0011 18.0 6.1 0.0012 17.9 4.3 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.5 GAM18338.1 - 0.019 15.1 1.8 0.024 14.8 1.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_RNA_Pol_19 PF05320.7 GAM18338.1 - 0.021 14.5 6.4 0.028 14.1 4.4 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Prothymosin PF03247.9 GAM18338.1 - 0.031 14.4 11.0 0.046 13.8 7.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4611 PF15387.1 GAM18338.1 - 0.23 11.5 8.8 0.42 10.7 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) CobT PF06213.7 GAM18338.1 - 0.28 10.2 9.5 0.34 10.0 6.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 GAM18338.1 - 0.46 8.4 7.6 0.5 8.3 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein VSG_B PF13206.1 GAM18338.1 - 0.79 8.7 7.5 0.83 8.7 5.2 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain Ndc1_Nup PF09531.5 GAM18338.1 - 1.3 7.4 3.8 1.3 7.3 2.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRN3 PF05327.6 GAM18338.1 - 3.5 5.6 8.1 3.7 5.5 5.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RhoGAP PF00620.22 GAM18339.1 - 3e-38 130.7 0.3 4.7e-38 130.1 0.2 1.3 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.20 GAM18340.1 - 2.4e-44 151.4 4.3 3.7e-44 150.8 0.1 2.5 3 0 0 3 3 3 1 Protein kinase domain Ribonuc_2-5A PF06479.7 GAM18340.1 - 1.2e-35 122.1 0.0 1.2e-35 122.1 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 GAM18340.1 - 1.2e-25 90.0 0.0 2.5e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 GAM18340.1 - 9.1e-08 31.8 0.2 3.3e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 PQQ-like domain Kinase-like PF14531.1 GAM18340.1 - 9.7e-05 21.4 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.16 GAM18340.1 - 0.00046 19.5 0.1 0.6 9.7 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat APH PF01636.18 GAM18340.1 - 0.039 13.6 1.1 0.24 11.1 0.3 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family DUF843 PF05814.6 GAM18340.1 - 0.12 12.1 4.7 0.13 12.0 0.6 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) SID-1_RNA_chan PF13965.1 GAM18340.1 - 1.2 7.2 9.6 0.31 9.1 3.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Zip PF02535.17 GAM18340.1 - 1.8 7.5 3.8 0.96 8.3 0.8 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter IncA PF04156.9 GAM18340.1 - 10 5.6 13.4 2 7.9 4.6 2.4 2 0 0 2 2 2 0 IncA protein PARP PF00644.15 GAM18341.1 - 4.4e-71 238.5 0.2 2.1e-70 236.3 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAM18341.1 - 4.4e-42 142.8 3.1 1.1e-41 141.5 2.2 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.13 GAM18341.1 - 2.1e-15 56.7 0.1 5.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 GAM18341.1 - 2.5e-15 55.5 2.6 3.1e-15 55.3 0.1 2.3 2 0 0 2 2 2 1 PADR1 (NUC008) domain WGR PF05406.10 GAM18341.1 - 2e-13 50.0 0.5 4.7e-13 48.9 0.3 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 GAM18341.1 - 0.0042 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SCO1-SenC PF02630.9 GAM18344.1 - 9e-44 149.1 0.0 1.5e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Pex14_N PF04695.8 GAM18344.1 - 0.00031 20.8 2.8 0.00051 20.0 1.9 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioredoxin_8 PF13905.1 GAM18344.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAM18344.1 - 0.0007 19.2 0.0 0.0015 18.1 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4366 PF14283.1 GAM18344.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Basic PF01586.11 GAM18344.1 - 0.12 13.1 0.1 0.26 12.0 0.1 1.5 1 0 0 1 1 1 0 Myogenic Basic domain DUF912 PF06024.7 GAM18344.1 - 0.2 11.7 1.2 0.42 10.6 0.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Macoilin PF09726.4 GAM18344.1 - 8.9 4.4 8.6 12 4.0 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein MmgE_PrpD PF03972.9 GAM18345.1 - 2.1e-153 510.6 0.0 2.5e-153 510.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family EMP24_GP25L PF01105.19 GAM18347.1 - 7.3e-50 169.2 0.4 9.2e-50 168.8 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FNIP PF05725.7 GAM18349.1 - 4.5e-46 154.5 25.2 1.7e-10 40.6 0.0 10.4 7 3 2 10 10 10 9 FNIP Repeat ubiquitin PF00240.18 GAM18350.1 - 1.2e-34 117.4 0.6 2.1e-34 116.7 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 GAM18350.1 - 9.5e-24 82.9 1.9 1.8e-23 82.0 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 GAM18350.1 - 2.3e-19 68.8 0.4 3.7e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM18350.1 - 1.6e-05 25.0 0.1 7.2e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM18350.1 - 0.001 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM18350.1 - 0.0012 18.6 0.2 0.0025 17.7 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 GAM18350.1 - 0.0079 16.0 0.4 0.012 15.4 0.3 1.3 1 0 0 1 1 1 1 IBR domain zf-CGNR PF11706.3 GAM18350.1 - 0.0087 15.5 0.2 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 CGNR zinc finger DUF2407 PF10302.4 GAM18350.1 - 0.012 15.7 0.3 0.016 15.3 0.2 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM18350.1 - 0.058 13.4 0.1 0.17 11.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 GAM18350.1 - 0.093 11.0 0.7 2.9 6.1 0.0 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain AAA_22 PF13401.1 GAM18351.1 - 1.6e-08 34.7 3.0 0.071 13.2 0.0 6.5 6 1 0 7 7 7 3 AAA domain AAA PF00004.24 GAM18351.1 - 8.7e-08 32.4 0.1 2.9e-05 24.2 0.0 4.8 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM18351.1 - 0.0011 19.0 0.0 2 8.3 0.0 4.7 6 0 0 6 6 6 1 AAA ATPase domain AAA_5 PF07728.9 GAM18351.1 - 0.0014 18.3 0.2 8 6.1 0.0 4.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 GAM18351.1 - 0.0088 14.9 0.7 0.37 9.6 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein CoA_transf_3 PF02515.12 GAM18351.1 - 0.035 13.3 0.0 0.085 12.0 0.0 1.6 1 0 0 1 1 1 0 CoA-transferase family III Mg_chelatase PF01078.16 GAM18351.1 - 0.071 12.2 0.0 9.8 5.2 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 GAM18351.1 - 0.21 11.1 0.0 39 3.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 GAM18351.1 - 0.22 10.8 0.1 6.5 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain Herpes_capsid PF06112.6 GAM18351.1 - 7.3 6.6 15.0 19 5.3 10.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MFS_1 PF07690.11 GAM18353.1 - 4.6e-50 170.2 38.1 4.7e-40 137.3 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM18353.1 - 7.4e-09 34.6 4.9 7.4e-09 34.6 3.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 GAM18353.1 - 0.00038 18.7 13.0 0.013 13.6 2.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector ADH_N PF08240.7 GAM18355.1 - 8.6e-24 83.3 2.3 1.8e-23 82.3 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM18355.1 - 3e-22 78.5 0.1 4.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM18355.1 - 0.00027 21.8 0.0 0.00097 20.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAM18355.1 - 0.0031 17.0 0.5 0.0089 15.6 0.2 1.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.11 GAM18355.1 - 0.0075 15.8 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein TrkA_N PF02254.13 GAM18355.1 - 0.039 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain bZIP_1 PF00170.16 GAM18356.1 - 1.3e-10 41.1 4.5 2.4e-10 40.2 3.1 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM18356.1 - 2.5e-08 33.5 4.7 2.6e-08 33.5 2.3 1.7 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 GAM18356.1 - 0.0045 17.2 4.4 0.0068 16.6 3.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor PBP1_TM PF14812.1 GAM18356.1 - 0.03 14.6 3.3 0.052 13.8 2.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ldh_1_C PF02866.13 GAM18357.1 - 4e-38 130.8 0.2 7.1e-38 130.0 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 GAM18357.1 - 7.8e-33 113.2 0.5 1.3e-32 112.6 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain HTH_Tnp_4 PF13613.1 GAM18357.1 - 0.17 11.4 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease SR-25 PF10500.4 GAM18358.1 - 0.025 14.0 3.7 0.041 13.3 2.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.2 GAM18359.1 - 0.0023 18.2 0.1 0.09 13.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) TPT PF03151.11 GAM18360.1 - 2.3e-16 59.8 32.7 7.6e-16 58.1 9.1 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 GAM18360.1 - 1.4e-11 43.8 30.3 2.5e-11 43.0 21.0 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM18360.1 - 2.5e-07 30.7 32.8 0.00088 19.3 7.7 2.8 2 2 0 2 2 2 2 EamA-like transporter family DUF4448 PF14610.1 GAM18360.1 - 1.5 8.2 4.4 0.49 9.8 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) BTB_2 PF02214.17 GAM18361.1 - 5.4e-23 81.0 0.2 1.5e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Fis1_TPR_C PF14853.1 GAM18361.1 - 4.4e-06 26.4 0.1 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 GAM18361.1 - 8.5e-06 26.0 0.1 2.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 GAM18361.1 - 6e-05 22.2 0.2 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_14 PF13428.1 GAM18361.1 - 0.00065 20.1 0.0 0.0021 18.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM18361.1 - 0.00079 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM18361.1 - 0.0012 18.4 0.1 0.0025 17.4 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 GAM18361.1 - 0.0023 18.5 0.0 0.0057 17.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM18361.1 - 0.0054 16.8 0.1 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 GAM18361.1 - 0.013 15.3 0.2 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM18361.1 - 0.015 15.6 0.0 0.043 14.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM18361.1 - 0.023 14.2 0.4 0.043 13.4 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Phosphoesterase PF04185.9 GAM18362.1 - 1.7e-91 307.2 2.3 2.4e-91 306.7 1.6 1.1 1 0 0 1 1 1 1 Phosphoesterase family CH PF00307.26 GAM18363.1 - 5.2e-11 42.5 0.3 2e-10 40.6 0.2 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.12 GAM18363.1 - 2.3e-06 27.2 0.1 6.1e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Ribonucleas_3_3 PF14622.1 GAM18364.1 - 9.5e-21 74.0 0.0 6.1e-10 39.1 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 GAM18364.1 - 4e-14 53.0 0.4 7.5e-06 26.3 0.0 3.3 2 2 0 2 2 2 2 Ribonuclease III domain dsrm PF00035.20 GAM18364.1 - 0.00011 22.6 0.0 0.00026 21.4 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif PAT1 PF09770.4 GAM18364.1 - 4.4 5.4 19.0 6.8 4.8 13.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Extensin_2 PF04554.8 GAM18364.1 - 5.1 7.0 61.3 0.34 10.8 25.5 2.5 1 1 1 2 2 2 0 Extensin-like region Methyltransf_16 PF10294.4 GAM18365.1 - 3.4e-21 75.4 2.0 1.8e-20 73.0 1.4 2.1 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAM18365.1 - 2.8e-06 26.8 0.2 4.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAM18365.1 - 8.5e-06 26.3 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM18365.1 - 0.0028 16.8 0.5 0.0055 15.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 GAM18365.1 - 0.0033 16.5 0.2 0.0063 15.6 0.1 1.5 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 GAM18365.1 - 0.0066 16.0 0.3 0.026 14.1 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM18365.1 - 0.012 16.0 0.1 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_8 PF01270.12 GAM18365.1 - 0.024 13.3 0.1 0.076 11.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 8 RrnaAD PF00398.15 GAM18365.1 - 0.03 13.3 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 GAM18365.1 - 0.077 12.5 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FlaC_arch PF05377.6 GAM18366.1 - 3.6 7.5 22.5 2 8.3 0.2 7.0 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) Patatin PF01734.17 GAM18367.1 - 2.1e-20 73.5 1.0 3.9e-20 72.6 0.7 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Med14 PF08638.6 GAM18369.1 - 2e-43 147.9 1.0 5.6e-43 146.4 0.0 2.3 2 0 0 2 2 2 1 Mediator complex subunit MED14 SWM_repeat PF13753.1 GAM18369.1 - 0.13 11.2 0.8 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Putative flagellar system-associated repeat ABC2_membrane PF01061.19 GAM18370.1 - 1.1e-73 246.8 56.5 4.4e-40 137.1 13.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM18370.1 - 1.3e-38 132.3 1.4 2e-25 89.7 0.0 4.0 3 1 1 4 4 3 3 ABC transporter AAA_21 PF13304.1 GAM18370.1 - 6.7e-12 45.9 0.1 0.016 15.2 0.0 5.5 4 1 1 5 5 5 2 AAA domain DUF258 PF03193.11 GAM18370.1 - 3.8e-06 26.1 0.0 0.00046 19.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM18370.1 - 3.8e-06 27.0 0.0 0.13 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM18370.1 - 2e-05 24.0 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM18370.1 - 3e-05 24.0 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 GAM18370.1 - 4.1e-05 23.0 0.3 0.0027 17.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM18370.1 - 0.00018 21.8 3.8 0.0067 16.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 GAM18370.1 - 0.00032 20.5 0.0 0.15 12.0 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 GAM18370.1 - 0.00064 20.5 0.1 0.013 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM18370.1 - 0.00076 19.4 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 GAM18370.1 - 0.0054 15.8 0.0 0.4 9.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 GAM18370.1 - 0.0076 16.2 0.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAM18370.1 - 0.0087 15.7 0.6 4.8 6.8 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B CPT PF07931.7 GAM18370.1 - 0.012 15.2 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 GAM18370.1 - 0.012 15.5 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RRP7 PF12923.2 GAM18370.1 - 0.028 14.4 2.6 0.059 13.4 1.8 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Miro PF08477.8 GAM18370.1 - 0.044 14.2 0.0 0.84 10.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 GAM18370.1 - 0.066 12.8 0.1 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 GAM18370.1 - 0.097 11.4 0.0 0.42 9.3 0.0 1.8 2 0 0 2 2 2 0 ArgK protein Myc_N PF01056.13 GAM18370.1 - 2.2 7.3 9.7 4.1 6.4 6.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region FNIP PF05725.7 GAM18371.1 - 8e-20 70.5 15.0 9.7e-11 41.4 0.6 3.8 5 0 0 5 5 5 2 FNIP Repeat DNA_pol_B_2 PF03175.8 GAM18373.1 - 0.0055 15.4 0.0 0.0075 14.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral FNIP PF05725.7 GAM18375.1 - 3.2e-51 171.0 28.3 2.7e-12 46.4 0.3 8.1 3 2 4 9 9 9 8 FNIP Repeat LRR_5 PF13306.1 GAM18375.1 - 0.0013 18.4 1.9 0.013 15.2 0.1 3.0 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) FNIP PF05725.7 GAM18376.1 - 5.6e-47 157.4 13.5 5.7e-15 55.0 0.0 7.5 6 2 2 9 9 9 6 FNIP Repeat DUF1769 PF08588.5 GAM18376.1 - 0.0013 18.6 0.2 20 5.2 0.0 3.9 2 1 1 3 3 3 3 Protein of unknown function (DUF1769) LRR_5 PF13306.1 GAM18376.1 - 0.098 12.3 0.1 0.25 11.0 0.1 1.7 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) DMAP1 PF05499.7 GAM18377.1 - 0.0094 15.5 1.3 0.013 15.0 0.9 1.1 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) HALZ PF02183.13 GAM18377.1 - 0.035 13.8 0.8 0.077 12.7 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper LCD1 PF09798.4 GAM18377.1 - 0.31 8.9 5.0 0.39 8.6 3.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Kelch_6 PF13964.1 GAM18378.1 - 1.2e-11 44.2 7.9 3.7e-05 23.6 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM18378.1 - 6.9e-10 38.5 4.5 0.0038 16.9 0.1 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM18378.1 - 8e-08 32.2 3.4 0.021 14.9 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-B_box PF00643.19 GAM18378.1 - 2.1e-07 30.7 10.0 4e-07 29.8 6.9 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.20 GAM18378.1 - 4.3e-07 29.3 5.3 0.0016 17.9 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAM18378.1 - 0.00022 20.8 7.7 0.2 11.4 0.0 5.0 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 GAM18378.1 - 0.0007 19.4 5.5 0.084 12.8 0.1 3.6 3 0 0 3 3 3 1 Kelch motif Baculo_PEP_C PF04513.7 GAM18378.1 - 0.0014 18.4 2.8 0.0028 17.4 1.9 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Rogdi_lz PF10259.4 GAM18378.1 - 0.03 13.4 1.0 3.2 6.7 0.0 2.2 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein zf-nanos PF05741.8 GAM18378.1 - 0.19 11.6 4.7 0.4 10.7 3.2 1.4 1 0 0 1 1 1 0 Nanos RNA binding domain Kelch_4 PF13418.1 GAM18379.1 - 5.7e-15 54.8 2.9 0.00085 19.0 0.0 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM18379.1 - 8.7e-15 54.1 5.3 0.00021 21.3 0.0 5.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 GAM18379.1 - 4.7e-08 32.9 0.7 0.76 10.0 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM18379.1 - 6.1e-08 32.0 4.0 0.046 13.2 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 GAM18379.1 - 6.7e-06 25.9 1.3 0.071 13.0 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 GAM18379.1 - 0.00012 21.6 5.8 0.22 11.3 0.0 4.7 6 0 0 6 6 6 2 Kelch motif Baculo_PEP_C PF04513.7 GAM18379.1 - 0.054 13.3 2.1 0.14 11.9 1.4 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM18379.1 - 0.18 11.6 1.6 0.72 9.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Kelch_6 PF13964.1 GAM18380.1 - 7.4e-14 51.2 5.3 2.9e-06 27.2 0.0 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM18380.1 - 3e-09 36.4 7.1 0.0021 17.8 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM18380.1 - 6.5e-09 35.1 0.4 0.0058 16.1 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM18380.1 - 9.1e-09 35.2 0.4 0.073 13.2 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM18380.1 - 1.9e-08 33.7 0.5 0.042 13.6 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM18380.1 - 4.9e-06 26.3 3.5 0.026 14.4 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Baculo_PEP_C PF04513.7 GAM18380.1 - 0.0043 16.8 0.6 0.0083 15.9 0.4 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3829 PF12889.2 GAM18380.1 - 0.0043 16.2 0.7 0.0071 15.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) UPF0231 PF06062.6 GAM18380.1 - 0.035 13.9 0.4 0.086 12.7 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) PA28_beta PF02252.13 GAM18380.1 - 0.038 13.4 0.1 0.076 12.4 0.1 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit DUF2408 PF10303.4 GAM18380.1 - 0.12 12.4 1.7 0.46 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) RPW8 PF05659.6 GAM18380.1 - 0.15 11.6 0.9 0.33 10.4 0.2 2.0 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4618 PF15397.1 GAM18380.1 - 0.48 9.7 4.1 0.1 11.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.7 GAM18380.1 - 0.51 10.6 2.9 7.2 6.9 0.8 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TnpB_IS66 PF05717.8 GAM18381.1 - 0.0081 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 IS66 Orf2 like protein Pescadillo_N PF06732.6 GAM18382.1 - 1.8e-97 325.9 7.6 1.8e-97 325.9 5.3 2.1 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 GAM18382.1 - 1.9e-10 40.7 0.0 7.2e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3439 PF11921.3 GAM18382.1 - 3.9 7.2 23.5 1.8 8.3 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HIT PF01230.18 GAM18383.1 - 1.2e-23 83.4 0.0 4e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 GAM18383.1 - 2.8e-19 69.4 0.0 1e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Tim17 PF02466.14 GAM18384.1 - 7.7e-08 32.4 3.5 9.3e-08 32.1 1.6 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family BAF1_ABF1 PF04684.8 GAM18384.1 - 0.55 9.0 20.9 0.71 8.6 14.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AIF-MLS PF14962.1 GAM18384.1 - 8.8 5.9 5.8 13 5.3 4.1 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Yippee-Mis18 PF03226.9 GAM18385.1 - 4.2e-16 58.7 0.9 4.2e-16 58.7 0.6 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3439 PF11921.3 GAM18385.1 - 0.027 14.2 3.8 0.054 13.2 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kinase-like PF14531.1 GAM18385.1 - 0.093 11.6 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.20 GAM18387.1 - 8.1e-29 100.6 0.9 8.1e-29 100.6 0.6 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM18387.1 - 2.6e-14 53.5 0.2 3.4e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM18387.1 - 8.4e-11 41.8 0.2 1.4e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM18387.1 - 1.6e-05 24.2 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM18387.1 - 0.015 15.3 0.1 0.025 14.5 0.1 1.4 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM18387.1 - 0.028 13.3 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 GAM18388.1 - 4.1e-28 98.4 0.0 5.5e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM18388.1 - 8.1e-16 58.5 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM18388.1 - 4.5e-09 36.2 0.0 6.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM18388.1 - 4.3e-07 30.1 0.0 6.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 GAM18388.1 - 1.5e-05 24.3 0.0 1.9e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM18388.1 - 0.00051 19.5 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM18388.1 - 0.00072 18.5 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Erf4 PF10256.4 GAM18389.1 - 0.0045 16.8 2.2 0.035 13.9 1.5 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family O-antigen_lig PF13425.1 GAM18389.1 - 0.033 14.1 1.7 0.044 13.7 1.2 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF843 PF05814.6 GAM18389.1 - 0.044 13.5 3.9 0.12 12.1 2.5 1.8 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF3810 PF12725.2 GAM18389.1 - 0.053 12.4 2.6 0.066 12.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Herpes_LMP1 PF05297.6 GAM18389.1 - 0.056 12.3 0.4 0.064 12.1 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EMP70 PF02990.11 GAM18390.1 - 2.7e-25 88.8 27.8 1.3e-17 63.5 8.4 2.1 2 0 0 2 2 2 2 Endomembrane protein 70 SR-25 PF10500.4 GAM18391.1 - 3.1e-12 46.4 0.7 3.5e-12 46.3 0.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein EF-hand_4 PF12763.2 GAM18392.1 - 2.3e-14 53.0 0.0 6e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 GAM18392.1 - 0.00011 21.2 0.1 0.00023 20.2 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 GAM18392.1 - 0.002 17.4 0.1 0.0043 16.3 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAM18392.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 GAM18392.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM18392.1 - 0.15 12.0 2.1 0.43 10.6 0.6 2.2 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Phostensin_N PF13916.1 GAM18392.1 - 3.8 7.5 5.3 0.66 9.9 0.3 2.0 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal KOW PF00467.24 GAM18393.1 - 8.6e-10 37.9 0.4 2.8e-09 36.3 0.3 1.8 2 0 0 2 2 2 1 KOW motif Ribosomal_L28e PF01778.12 GAM18394.1 - 1.2e-29 103.1 0.3 1.2e-29 103.1 0.2 2.0 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 GAM18394.1 - 1.7e-17 63.3 17.7 1.7e-17 63.3 12.3 2.6 1 1 1 2 2 2 1 Mak16 protein C-terminal region Cwf_Cwc_15 PF04889.7 GAM18394.1 - 0.17 11.5 18.6 0.26 10.9 12.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 GAM18394.1 - 1.2 7.5 25.6 1.5 7.2 17.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 GAM18394.1 - 2.8 5.8 22.2 5.3 4.9 15.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.13 GAM18395.1 - 5.8e-06 26.1 7.9 1.3e-05 25.0 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.6 GAM18395.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold TauE PF01925.14 GAM18396.1 - 2.3e-22 79.6 26.0 7.4e-11 41.9 1.4 2.1 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE DUF4131 PF13567.1 GAM18396.1 - 0.011 15.1 7.7 3.6 6.9 0.9 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) SK_channel PF03530.9 GAM18396.1 - 0.31 10.8 6.2 0.14 11.9 1.6 2.2 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Josephin PF02099.12 GAM18397.1 - 1.4e-08 34.5 0.1 2.1e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Josephin MENTAL PF10457.4 GAM18397.1 - 0.014 14.9 0.3 0.021 14.4 0.1 1.3 1 1 0 1 1 1 0 Cholesterol-capturing domain ABC_tran PF00005.22 GAM18398.1 - 4.7e-28 98.1 0.1 9.1e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 GAM18398.1 - 6.8e-28 97.2 31.1 1e-27 96.6 21.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 GAM18398.1 - 4e-08 33.5 0.1 6.8e-06 26.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAM18398.1 - 1.6e-05 24.4 0.0 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM18398.1 - 7.2e-05 22.0 0.1 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM18398.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 GAM18398.1 - 0.00025 21.2 0.0 0.0017 18.5 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM18398.1 - 0.00033 20.8 0.1 0.0018 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM18398.1 - 0.00044 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_15 PF13175.1 GAM18398.1 - 0.0012 17.9 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 GAM18398.1 - 0.0013 18.0 0.1 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 GAM18398.1 - 0.0017 18.1 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 GAM18398.1 - 0.0032 18.2 0.0 0.0072 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 GAM18398.1 - 0.0038 16.7 0.1 0.0069 15.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 GAM18398.1 - 0.0053 15.4 0.0 0.0077 14.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 GAM18398.1 - 0.0073 16.2 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM18398.1 - 0.0075 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM18398.1 - 0.012 15.5 0.0 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 GAM18398.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 GAM18398.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 GAM18398.1 - 0.019 14.8 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_35 PF14516.1 GAM18398.1 - 0.023 13.3 0.0 0.044 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 GAM18398.1 - 0.03 13.8 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 GAM18398.1 - 0.033 13.6 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain PDR_CDR PF06422.7 GAM18398.1 - 0.042 13.5 0.2 0.042 13.5 0.1 2.4 2 0 0 2 2 2 0 CDR ABC transporter HrpA_pilin PF09589.5 GAM18398.1 - 0.048 14.0 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 1 0 HrpA pilus formation protein AAA_5 PF07728.9 GAM18398.1 - 0.059 13.0 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAM18398.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 GAM18398.1 - 0.073 12.4 0.2 0.18 11.1 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 GAM18398.1 - 0.075 12.9 0.1 0.21 11.5 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAM18398.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 GAM18398.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAM18398.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CAP PF00188.21 GAM18400.1 - 6.4e-10 39.5 0.0 1.9e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RNA_polI_A34 PF08208.6 GAM18400.1 - 0.052 13.2 24.4 0.078 12.6 16.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF1510 PF07423.6 GAM18400.1 - 0.18 11.1 17.6 0.28 10.5 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 GAM18400.1 - 1.7 8.6 19.8 2.5 8.1 13.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 GAM18400.1 - 2.3 8.0 11.7 4 7.2 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 GAM18400.1 - 2.4 6.0 13.6 3.1 5.7 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 GAM18400.1 - 4 6.0 17.9 5.8 5.5 12.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DEAD PF00270.24 GAM18401.1 - 2.8e-46 157.1 0.0 6.4e-46 155.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM18401.1 - 9.9e-26 89.4 0.9 4.7e-25 87.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VWA_2 PF13519.1 GAM18402.1 - 4.9e-08 33.2 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM18402.1 - 7e-05 22.6 0.2 0.00052 19.7 0.2 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAM18402.1 - 0.00023 21.0 1.3 0.00074 19.3 0.1 2.4 2 1 0 2 2 2 1 vWA found in TerF C terminus Abi PF02517.11 GAM18404.1 - 0.0011 19.0 17.3 0.0011 19.0 12.0 2.6 2 1 0 2 2 2 1 CAAX protease self-immunity DUF4131 PF13567.1 GAM18404.1 - 0.23 10.8 0.0 0.23 10.8 0.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_L7Ae PF01248.21 GAM18405.1 - 0.026 14.0 0.0 0.077 12.5 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_11 PF13086.1 GAM18405.1 - 0.17 11.4 9.9 0.47 9.9 5.8 2.0 1 1 1 2 2 2 0 AAA domain DUF3087 PF11286.3 GAM18405.1 - 1.2 8.3 4.9 0.89 8.7 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) DUF106 PF01956.11 GAM18405.1 - 6.8 6.2 8.3 5.6 6.4 4.7 1.6 1 1 1 2 2 2 0 Integral membrane protein DUF106 DEAD PF00270.24 GAM18406.1 - 5.3e-33 113.8 0.1 2.2e-32 111.8 0.0 2.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM18406.1 - 6.7e-22 77.1 0.0 2.1e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM18406.1 - 3.6e-08 33.4 0.0 1.1e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ank_4 PF13637.1 GAM18406.1 - 0.034 14.6 0.0 13 6.4 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-C3HC4_2 PF13923.1 GAM18407.1 - 2.8e-06 27.2 10.5 2.8e-06 27.2 7.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM18407.1 - 0.0011 18.5 17.1 0.016 14.8 7.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM18407.1 - 0.002 17.7 8.8 0.002 17.7 6.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AT_hook PF02178.14 GAM18407.1 - 0.0082 15.7 20.0 0.056 13.1 2.9 2.6 2 0 0 2 2 2 2 AT hook motif zf-RING_2 PF13639.1 GAM18407.1 - 1.1 9.1 24.0 0.088 12.6 10.1 2.8 3 0 0 3 3 3 0 Ring finger domain zf-Apc11 PF12861.2 GAM18407.1 - 1.5 8.6 10.7 1.4 8.8 5.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAM18407.1 - 1.6 8.5 18.8 0.2 11.4 7.6 3.0 3 0 0 3 3 3 0 zinc-RING finger domain DUF3245 PF11595.3 GAM18407.1 - 4.9 7.4 12.9 1.2 9.4 4.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF2946 PF11162.3 GAM18407.1 - 5.9 7.1 10.9 1.1 9.5 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) Histone PF00125.19 GAM18408.1 - 7.1e-32 109.3 0.2 1e-31 108.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM18408.1 - 3.1e-05 24.0 0.0 4.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 GAM18408.1 - 0.0081 15.4 0.1 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T IKI3 PF04762.7 GAM18409.1 - 8e-249 828.1 0.0 2.5e-248 826.5 0.0 1.7 2 0 0 2 2 2 1 IKI3 family Apc4_WD40 PF12894.2 GAM18409.1 - 0.00032 20.1 0.0 0.021 14.3 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 GAM18409.1 - 2.4 8.1 10.2 25 4.9 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat UCH PF00443.24 GAM18410.1 - 5.4e-82 274.9 0.0 1.5e-81 273.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM18410.1 - 3.1e-22 79.3 0.1 4e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAM18410.1 - 1.1e-13 51.3 0.7 1.1e-13 51.3 0.5 3.2 4 0 0 4 4 4 1 DUSP domain Ubiquitin_3 PF14836.1 GAM18410.1 - 2e-08 33.7 0.0 5e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain SNARE PF05739.14 GAM18412.1 - 2.1e-12 46.5 5.4 5.5e-12 45.1 2.7 2.4 2 0 0 2 2 2 1 SNARE domain Rifin_STEVOR PF02009.11 GAM18412.1 - 0.0089 15.6 0.8 0.013 15.2 0.6 1.3 1 0 0 1 1 1 1 Rifin/stevor family Phage_Gp23 PF10669.4 GAM18412.1 - 0.012 15.6 2.3 0.012 15.6 1.6 2.6 1 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) ABC2_membrane_3 PF12698.2 GAM18412.1 - 0.027 13.4 3.8 0.035 13.1 2.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein BPD_transp_2 PF02653.11 GAM18412.1 - 0.036 13.0 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component YlqD PF11068.3 GAM18412.1 - 0.67 9.9 5.4 1 9.3 2.3 2.1 2 0 0 2 2 2 0 YlqD protein NYD-SP28 PF14772.1 GAM18412.1 - 1.2 9.3 6.2 1.6 8.8 0.1 2.7 2 1 0 2 2 2 0 Sperm tail ZYG-11_interact PF05884.7 GAM18412.1 - 2.7 7.0 5.6 0.45 9.5 0.1 2.2 1 1 1 2 2 2 0 Interactor of ZYG-11 Fib_alpha PF08702.5 GAM18412.1 - 3.7 7.6 12.1 1.2 9.2 3.4 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family tRNA-synt_2b PF00587.20 GAM18413.1 - 9.1e-37 126.2 0.1 1.5e-36 125.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAM18413.1 - 4.2e-16 58.8 3.4 4.2e-16 58.8 2.3 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CENP-K PF11802.3 GAM18413.1 - 0.029 13.6 0.4 0.062 12.5 0.3 1.6 1 0 0 1 1 1 0 Centromere-associated protein K DUF211 PF02680.9 GAM18413.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 DNA_pol_B_2 PF03175.8 GAM18415.1 - 0.015 14.0 0.2 0.018 13.7 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Lipoprotein_21 PF14041.1 GAM18417.1 - 0.003 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 LppP/LprE lipoprotein DARPP-32 PF05395.7 GAM18417.1 - 0.054 13.6 2.5 3.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Gelsolin PF00626.17 GAM18418.1 - 5.1e-34 115.8 0.0 1.2e-07 31.3 0.0 5.8 5 0 0 5 5 5 5 Gelsolin repeat PBD PF00786.23 GAM18418.1 - 1.5e-06 28.5 0.1 1.5e-06 28.5 0.1 4.5 4 0 0 4 4 4 1 P21-Rho-binding domain WASH-7_N PF14745.1 GAM18419.1 - 2.9e-203 676.1 3.4 5.4e-203 675.2 2.3 1.5 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.1 GAM18419.1 - 1e-155 517.9 6.6 1.9e-155 516.9 4.6 1.5 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.1 GAM18419.1 - 2.8e-62 209.2 5.4 6.8e-62 208.0 3.7 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Peptidase_M28 PF04389.12 GAM18422.1 - 5.8e-21 75.0 0.0 8.2e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 GAM18422.1 - 4e-05 22.9 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 2 Nicastrin Peptidase_M20 PF01546.23 GAM18422.1 - 0.0015 18.0 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 EF1_GNE PF00736.14 GAM18423.1 - 9.8e-33 111.7 0.6 1.8e-32 110.8 0.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 GAM18423.1 - 0.00085 19.4 6.7 0.00085 19.4 4.7 1.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 GAM18423.1 - 0.0024 18.3 0.0 0.0067 16.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM18423.1 - 0.0027 17.6 0.2 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM18423.1 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acyltransferase PF01553.16 GAM18426.1 - 1.2e-12 47.3 0.0 2.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase LRR_6 PF13516.1 GAM18427.1 - 1.2e-13 49.5 29.6 0.049 13.7 0.1 11.4 11 1 1 12 12 12 6 Leucine Rich repeat LRR_8 PF13855.1 GAM18427.1 - 2e-10 40.2 36.3 5.6e-05 22.8 0.7 7.3 4 2 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 GAM18427.1 - 4.6e-10 38.8 33.9 0.24 11.0 0.0 9.1 6 2 4 11 11 11 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM18427.1 - 7.4e-10 37.4 26.3 0.5 10.5 0.0 10.9 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_7 PF13504.1 GAM18427.1 - 0.0028 17.5 28.1 4 8.0 0.1 9.9 11 1 1 12 12 12 2 Leucine rich repeat Ras PF00071.17 GAM18428.1 - 2e-44 150.8 0.8 2.2e-44 150.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM18428.1 - 9.1e-14 51.9 0.2 1.6e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM18428.1 - 1e-08 34.5 0.1 1.3e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM18428.1 - 7.7e-08 31.9 0.7 9.2e-07 28.4 0.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM18428.1 - 0.00036 20.4 0.4 0.00066 19.6 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM18428.1 - 0.0019 18.0 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 GAM18428.1 - 0.035 13.6 0.2 0.16 11.5 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 GAM18428.1 - 0.084 13.0 0.1 2.1 8.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 GAM18428.1 - 0.093 12.0 0.3 0.43 9.8 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Tetraspannin PF00335.15 GAM18429.1 - 0.0005 19.4 21.5 0.0005 19.4 14.9 2.0 1 1 0 2 2 2 1 Tetraspanin family Grp1_Fun34_YaaH PF01184.14 GAM18429.1 - 0.11 11.7 9.1 0.14 11.4 6.3 1.1 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family MFS_2 PF13347.1 GAM18429.1 - 1.5 7.1 15.7 2 6.7 10.8 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein Yip1 PF04893.12 GAM18429.1 - 3.3 7.1 23.7 10 5.5 16.4 1.9 1 1 0 1 1 1 0 Yip1 domain YfhO PF09586.5 GAM18429.1 - 3.4 5.5 9.2 4.6 5.1 6.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABC2_membrane_5 PF13346.1 GAM18429.1 - 4.6 6.4 24.8 0.18 11.0 11.8 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein CoA_binding_3 PF13727.1 GAM18429.1 - 9.3 6.0 10.0 2.9 7.6 4.9 1.7 1 1 0 1 1 1 0 CoA-binding domain Beta_helix PF13229.1 GAM18430.1 - 8.7e-06 25.5 92.4 2.7e-05 23.9 10.8 8.1 3 2 4 7 7 7 4 Right handed beta helix region Dak1 PF02733.12 GAM18430.1 - 0.0063 15.1 0.1 0.012 14.2 0.1 1.3 1 0 0 1 1 1 1 Dak1 domain Chlam_PMP PF02415.12 GAM18430.1 - 0.31 11.3 21.2 12 6.3 2.1 7.6 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat zf-UBR PF02207.15 GAM18431.1 - 2e-12 46.6 10.7 2e-12 46.6 7.4 3.7 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 GAM18431.1 - 1.3e-06 28.0 7.3 1.3e-06 28.0 5.1 3.8 3 1 0 3 3 3 1 PHD-finger MRP-L28 PF09812.4 GAM18431.1 - 0.012 15.4 1.7 0.012 15.4 1.2 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 DUF334 PF03904.8 GAM18431.1 - 2.8 7.1 6.3 6.4 6.0 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) SF3b1 PF08920.5 GAM18432.1 - 2.7e-35 121.5 2.3 3.7e-35 121.0 0.2 2.1 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 GAM18432.1 - 4e-17 62.2 3.0 0.11 12.7 0.0 7.1 5 2 2 7 7 7 6 HEAT repeats HEAT PF02985.17 GAM18432.1 - 3.7e-14 51.4 4.2 0.014 15.3 0.0 9.4 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 GAM18432.1 - 8.6e-09 35.6 0.1 3.8 8.1 0.0 7.7 8 2 3 11 11 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM18432.1 - 3e-05 24.3 4.1 1.4 9.3 0.0 5.2 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM18432.1 - 0.0011 18.3 0.9 1.3 8.3 0.0 3.6 3 1 0 3 3 3 1 CLASP N terminal Arm PF00514.18 GAM18432.1 - 0.0075 16.0 0.1 26 4.8 0.0 5.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat IFRD PF05004.8 GAM18432.1 - 0.011 14.8 0.4 0.025 13.6 0.2 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF2435 PF10363.4 GAM18432.1 - 0.017 15.0 1.0 0.14 12.0 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Cnd3 PF12719.2 GAM18432.1 - 0.041 12.8 1.2 7.7 5.3 0.0 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain ParcG PF10274.4 GAM18432.1 - 0.048 13.5 4.6 12 5.7 0.0 4.6 3 1 3 6 6 6 0 Parkin co-regulated protein B56 PF01603.15 GAM18432.1 - 0.05 12.2 1.5 2 6.9 0.0 3.4 3 2 1 4 4 4 0 Protein phosphatase 2A regulatory B subunit (B56 family) TIP120 PF08623.5 GAM18432.1 - 0.055 13.0 0.3 1.2 8.6 0.0 2.9 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Metallophos PF00149.23 GAM18434.1 - 3.8e-45 153.7 0.2 5e-45 153.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM18434.1 - 0.0069 16.2 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ku_PK_bind PF08785.6 GAM18435.1 - 1.6e-38 131.2 0.3 1.1e-37 128.5 0.0 2.6 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.10 GAM18435.1 - 1.7e-33 115.9 4.8 2.9e-33 115.1 3.4 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 GAM18435.1 - 1.7e-33 115.7 0.0 4.4e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 GAM18435.1 - 2.8e-09 37.3 1.6 8.3e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.23 GAM18435.1 - 0.0016 18.2 2.3 0.0068 16.1 1.6 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain SBP_bac_5 PF00496.17 GAM18435.1 - 0.0027 16.5 0.1 0.01 14.6 0.1 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle MGS PF02142.17 GAM18435.1 - 0.014 15.2 0.1 0.04 13.8 0.1 1.8 1 0 0 1 1 1 0 MGS-like domain Histone PF00125.19 GAM18437.1 - 7.1e-32 109.3 0.2 1e-31 108.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM18437.1 - 3.1e-05 24.0 0.0 4.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 GAM18437.1 - 0.0081 15.4 0.1 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Myotub-related PF06602.9 GAM18438.1 - 3e-66 223.6 0.2 3e-66 223.6 0.1 2.2 2 1 0 2 2 2 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.12 GAM18438.1 - 1.1e-51 175.3 0.0 3.2e-51 173.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM18438.1 - 2e-42 145.1 0.0 3.6e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 GAM18438.1 - 1.7e-33 113.6 58.1 6.1e-08 32.1 0.8 8.2 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18438.1 - 5.8e-25 86.8 50.9 2.5e-07 30.3 5.6 6.7 3 1 2 6 6 6 5 Leucine rich repeat WD40 PF00400.27 GAM18438.1 - 2.2e-13 49.5 22.0 3.1e-06 26.8 0.7 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Ras PF00071.17 GAM18438.1 - 3.6e-13 49.2 0.1 1.1e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAM18438.1 - 1.1e-12 48.5 0.1 5.1e-12 46.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein LRR_1 PF00560.28 GAM18438.1 - 1.1e-10 39.9 53.2 0.33 11.1 0.1 13.3 13 0 0 13 13 12 5 Leucine Rich Repeat LRR_7 PF13504.1 GAM18438.1 - 8.8e-05 22.1 46.7 1.6 9.2 0.1 11.6 11 0 0 11 11 11 2 Leucine rich repeat Arf PF00025.16 GAM18438.1 - 0.00038 19.7 0.7 0.0022 17.2 0.5 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM18438.1 - 0.00065 19.6 0.0 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase APH PF01636.18 GAM18438.1 - 0.7 9.5 0.0 1.3 8.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RGS PF00615.14 GAM18439.1 - 1.2e-19 70.5 1.7 2.5e-13 50.1 0.4 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain PRANC PF09372.5 GAM18439.1 - 0.013 15.4 1.6 0.1 12.5 0.2 2.5 2 0 0 2 2 2 0 PRANC domain dsDNA_bind PF01984.15 GAM18439.1 - 0.091 12.7 0.0 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Double-stranded DNA-binding domain SIT PF15330.1 GAM18439.1 - 0.78 9.8 4.1 0.66 10.1 0.1 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Xpo1 PF08389.7 GAM18440.1 - 3.3e-15 56.2 6.7 1.2e-13 51.1 0.3 4.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 GAM18440.1 - 0.00075 19.3 1.7 0.0037 17.1 1.2 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DNA_alkylation PF08713.6 GAM18440.1 - 0.017 14.6 0.1 0.071 12.6 0.1 2.0 2 0 0 2 2 2 0 DNA alkylation repair enzyme RasGEF_N PF00618.15 GAM18440.1 - 0.017 15.2 3.1 0.052 13.6 0.8 2.9 2 0 0 2 2 2 0 RasGEF N-terminal motif GLF PF03275.8 GAM18441.1 - 0.013 14.9 0.6 0.023 14.2 0.4 1.5 1 0 0 1 1 1 0 UDP-galactopyranose mutase SNARE PF05739.14 GAM18441.1 - 0.032 13.9 3.8 3.4 7.4 0.0 4.0 4 0 0 4 4 4 0 SNARE domain Activator-TraM PF11657.3 GAM18441.1 - 0.2 11.1 4.0 7 6.1 0.2 2.7 3 0 0 3 3 3 0 Transcriptional activator TraM RBFA PF02033.13 GAM18442.1 - 5.4e-06 26.3 0.2 0.0015 18.5 0.1 2.8 2 0 0 2 2 2 2 Ribosome-binding factor A ATP-grasp_4 PF13535.1 GAM18443.1 - 0.036 13.7 0.0 0.085 12.5 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain Macoilin PF09726.4 GAM18443.1 - 2.1 6.5 7.1 2.8 6.0 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Ras PF00071.17 GAM18445.1 - 3.3e-51 172.9 0.0 3.8e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM18445.1 - 2.1e-16 59.6 0.0 2.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM18445.1 - 1.3e-15 57.8 0.0 2.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM18445.1 - 1.1e-08 34.5 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM18445.1 - 1.1e-07 31.5 0.0 2.8e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM18445.1 - 0.00081 18.6 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAM18445.1 - 0.0016 17.9 0.1 0.26 10.7 0.0 2.3 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 GAM18445.1 - 0.0018 18.2 0.1 0.0024 17.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM18445.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Dynamin family Fib_alpha PF08702.5 GAM18446.1 - 0.0028 17.7 12.1 0.13 12.3 3.0 2.1 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family DUF2317 PF10079.4 GAM18446.1 - 0.017 13.7 8.8 0.022 13.4 6.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Kinetocho_Slk19 PF12709.2 GAM18446.1 - 0.03 14.4 0.8 0.03 14.4 0.6 2.5 1 1 1 2 2 2 0 Central kinetochore-associated DUF4200 PF13863.1 GAM18446.1 - 0.087 12.7 14.3 0.3 11.0 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) COOH-NH2_lig PF14395.1 GAM18446.1 - 0.094 11.7 2.8 0.13 11.2 1.4 1.6 1 1 1 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 DUF2067 PF09840.4 GAM18446.1 - 0.094 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Baculo_PEP_C PF04513.7 GAM18446.1 - 0.11 12.3 11.8 0.14 11.9 8.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.1 GAM18446.1 - 0.12 12.4 5.8 0.16 12.0 3.6 1.4 1 1 0 1 1 1 0 Up-regulated During Septation YvrJ PF12841.2 GAM18446.1 - 0.13 11.5 1.0 8.7 5.7 0.0 2.9 2 1 1 3 3 3 0 YvrJ protein family SYF2 PF08231.7 GAM18446.1 - 0.14 12.2 12.1 0.21 11.6 8.4 1.3 1 0 0 1 1 1 0 SYF2 splicing factor Mnd1 PF03962.10 GAM18446.1 - 0.16 11.6 10.4 0.3 10.7 7.2 1.5 1 1 0 1 1 1 0 Mnd1 family Tetraspannin PF00335.15 GAM18446.1 - 0.23 10.7 1.2 0.31 10.2 0.8 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF87 PF01935.12 GAM18446.1 - 0.27 11.0 2.0 0.32 10.7 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_13 PF13166.1 GAM18446.1 - 0.37 9.1 12.2 0.49 8.7 8.4 1.1 1 0 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 GAM18446.1 - 0.42 10.5 3.5 7.5 6.5 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 GAM18446.1 - 0.42 11.0 10.0 1.8 9.0 4.1 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HsbA PF12296.3 GAM18446.1 - 0.48 10.2 8.1 1.4 8.8 5.7 1.7 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Prefoldin PF02996.12 GAM18446.1 - 0.66 9.6 10.5 1.1 8.9 0.1 2.8 2 1 1 3 3 3 0 Prefoldin subunit Not3 PF04065.10 GAM18446.1 - 0.7 9.1 10.8 0.96 8.6 7.5 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component APG6 PF04111.7 GAM18446.1 - 0.74 8.7 13.3 1 8.3 9.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Filament PF00038.16 GAM18446.1 - 0.86 9.0 16.0 1.3 8.4 11.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Exonuc_VII_L PF02601.10 GAM18446.1 - 0.97 8.5 11.2 1.2 8.2 7.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Osmo_CC PF08946.5 GAM18446.1 - 1.2 9.2 8.1 8.2 6.5 0.5 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil TipAS PF07739.8 GAM18446.1 - 1.3 9.3 8.1 11 6.3 5.6 2.0 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain DUF4407 PF14362.1 GAM18446.1 - 2.1 7.2 19.6 0.19 10.6 9.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Muted PF14942.1 GAM18446.1 - 2.2 8.1 10.1 12 5.8 7.1 1.8 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1664 PF07889.7 GAM18446.1 - 2.8 7.7 6.3 6.2 6.6 4.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HR1 PF02185.11 GAM18446.1 - 2.8 7.7 16.1 0.8 9.4 3.8 2.2 1 1 1 2 2 2 0 Hr1 repeat DUF3584 PF12128.3 GAM18446.1 - 3.1 5.0 17.4 3.9 4.6 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fzo_mitofusin PF04799.8 GAM18446.1 - 3.8 6.8 11.0 8 5.8 6.0 2.0 1 1 1 2 2 2 0 fzo-like conserved region LUC7 PF03194.10 GAM18446.1 - 4.7 6.6 9.2 6.6 6.1 6.3 1.2 1 0 0 1 1 1 0 LUC7 N_terminus TMF_DNA_bd PF12329.3 GAM18446.1 - 5.5 6.8 8.6 1.3 8.8 1.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AIP3 PF03915.8 GAM18446.1 - 5.7 5.7 12.1 7.3 5.3 8.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Atg14 PF10186.4 GAM18446.1 - 7.5 5.3 17.0 15 4.3 11.8 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 GAM18446.1 - 7.6 6.9 9.6 5 7.5 4.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Pkinase PF00069.20 GAM18448.1 - 2.3e-47 161.3 0.0 3.6e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18448.1 - 6.2e-26 91.0 0.0 8.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM18448.1 - 0.048 12.6 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Methyltransf_16 PF10294.4 GAM18451.1 - 2e-14 53.4 0.1 2.4e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 GAM18451.1 - 0.037 13.1 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.9 GAM18451.1 - 0.059 12.7 0.1 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 GAM18451.1 - 0.07 12.2 0.3 0.094 11.8 0.2 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAM18451.1 - 0.072 13.6 0.3 0.12 12.9 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.17 GAM18452.1 - 9.1e-43 145.4 0.6 2.5e-42 144.0 0.1 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 GAM18452.1 - 1.8e-18 67.1 0.2 5.5e-18 65.5 0.2 1.9 1 0 0 1 1 1 1 Miro-like protein RNB PF00773.14 GAM18452.1 - 4.7e-13 49.1 2.2 2.1e-12 46.9 0.0 2.6 3 0 0 3 3 3 1 RNB domain Arf PF00025.16 GAM18452.1 - 1e-07 31.3 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM18452.1 - 0.00014 21.3 0.1 0.00042 19.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM18452.1 - 0.00017 21.4 0.1 0.0011 18.9 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GATA PF00320.22 GAM18453.1 - 6.9e-06 25.3 3.3 2e-05 23.8 2.3 1.8 1 0 0 1 1 1 1 GATA zinc finger zf-RING_5 PF14634.1 GAM18453.1 - 0.36 10.5 6.4 0.54 10.0 1.2 2.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM18453.1 - 0.41 10.3 10.7 0.1 12.2 1.1 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Oxysterol_BP PF01237.13 GAM18454.1 - 5.8e-75 251.9 10.6 1.5e-73 247.3 7.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Proteasome PF00227.21 GAM18455.1 - 4.6e-55 185.8 0.1 5.9e-55 185.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM18455.1 - 9.7e-14 50.3 0.1 1.9e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RhoGAP PF00620.22 GAM18456.1 - 7.8e-36 122.9 0.0 1.2e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.27 GAM18456.1 - 3.6e-06 26.6 10.0 0.031 14.1 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat FNIP PF05725.7 GAM18458.1 - 1.7e-80 264.6 18.6 1.8e-12 46.9 0.1 10.4 6 2 3 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM18458.1 - 1.3e-05 25.0 9.7 9.2 6.2 0.0 8.6 4 1 6 10 10 10 3 Protein of unknown function (DUF1769) Response_reg PF00072.19 GAM18459.1 - 9.8e-30 102.8 0.9 3.6e-22 78.4 0.3 4.9 4 1 0 4 4 4 3 Response regulator receiver domain HATPase_c PF02518.21 GAM18459.1 - 1.3e-24 85.9 0.1 2.9e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM18459.1 - 1.8e-14 53.5 0.2 4.6e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 GAM18459.1 - 4.1e-13 49.5 0.0 1.4e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 GAM18459.1 - 1.8e-08 34.1 0.0 4.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 GAM18459.1 - 1.4e-06 28.3 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 GAM18459.1 - 0.013 15.5 0.0 0.041 13.9 0.0 1.9 1 0 0 1 1 1 0 PAS fold REF PF05755.7 GAM18459.1 - 0.22 11.2 0.0 0.71 9.5 0.0 1.8 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) SNF2_N PF00176.18 GAM18460.1 - 8.3e-60 202.0 0.0 1.5e-59 201.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM18460.1 - 3.9e-12 45.8 0.0 8.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM18460.1 - 0.0055 16.5 0.0 0.026 14.3 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Sporozoite_P67 PF05642.6 GAM18461.1 - 0.011 13.6 12.6 0.015 13.2 8.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAM18461.1 - 0.44 10.3 10.0 0.77 9.5 6.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 GAM18461.1 - 0.98 9.1 7.3 1.6 8.5 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) SMC_N PF02463.14 GAM18462.1 - 1.7e-27 96.0 7.2 5.5e-27 94.4 5.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAM18462.1 - 2.4e-15 57.4 15.4 2.4e-15 57.4 10.7 5.2 3 2 1 4 4 2 1 AAA domain AAA_15 PF13175.1 GAM18462.1 - 0.00016 20.8 24.4 0.00016 20.8 16.9 2.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.1 GAM18462.1 - 0.0003 20.2 0.0 0.0008 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 GAM18462.1 - 0.00059 19.8 2.2 0.00059 19.8 1.5 3.2 4 0 0 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 GAM18462.1 - 0.0017 17.6 15.5 0.58 9.2 0.5 4.3 3 1 0 4 4 4 3 Reovirus sigma C capsid protein WEMBL PF05701.6 GAM18462.1 - 0.0025 16.3 14.0 0.0025 16.3 9.7 4.4 2 2 2 4 4 3 2 Weak chloroplast movement under blue light DUF374 PF04028.8 GAM18462.1 - 0.16 11.2 0.9 0.64 9.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF374) AAA_25 PF13481.1 GAM18462.1 - 0.97 8.7 4.7 2.3 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sec20 PF03908.8 GAM18462.1 - 1.3 8.7 10.4 5.3 6.8 0.5 4.4 2 1 2 4 4 4 0 Sec20 APG6 PF04111.7 GAM18462.1 - 1.6 7.6 80.8 0.0084 15.1 13.1 6.1 2 2 4 6 6 6 0 Autophagy protein Apg6 Spindle_Spc25 PF08234.7 GAM18463.1 - 0.016 15.1 0.2 0.45 10.5 0.1 2.5 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 Cyclin PF08613.6 GAM18464.1 - 0.00019 21.8 3.9 0.00019 21.8 2.7 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM18464.1 - 0.0014 18.1 0.7 0.0014 18.1 0.5 2.6 3 1 0 3 3 3 1 Cyclin, N-terminal domain Choline_transpo PF04515.7 GAM18465.1 - 2.1e-108 361.9 45.8 5.4e-108 360.6 23.9 3.0 3 0 0 3 3 3 3 Plasma-membrane choline transporter Pantoate_ligase PF02569.10 GAM18466.1 - 5.7e-81 271.3 0.1 6.8e-81 271.0 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase TFIIA PF03153.8 GAM18467.1 - 1.2 8.9 39.6 1.8 8.3 27.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 GAM18467.1 - 2.6 6.1 45.9 3.2 5.8 31.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ARGLU PF15346.1 GAM18467.1 - 4.1 7.1 19.5 4.9 6.9 3.3 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF3801 PF12687.2 GAM18467.1 - 5 6.6 19.5 0.45 10.0 1.0 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3801) DAO PF01266.19 GAM18469.1 - 7.9e-47 159.8 0.0 1.2e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM18469.1 - 1.8e-10 40.2 1.0 0.00014 20.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 GAM18469.1 - 1e-08 34.6 1.4 0.00016 20.9 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM18469.1 - 1.9e-05 24.6 0.0 0.0045 16.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM18469.1 - 3e-05 23.0 3.2 0.011 14.5 0.1 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 GAM18469.1 - 0.00086 18.4 0.4 0.51 9.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 GAM18469.1 - 0.001 18.1 0.0 0.29 10.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM18469.1 - 0.0011 18.9 0.3 0.0059 16.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM18469.1 - 0.018 13.4 0.3 0.036 12.5 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 GAM18469.1 - 0.16 12.3 0.6 0.44 10.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 GAM18469.1 - 0.31 10.6 1.9 0.48 10.0 0.0 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S7e PF01251.13 GAM18471.1 - 6.8e-77 257.2 4.9 7.9e-77 257.0 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Actin PF00022.14 GAM18472.1 - 2.5e-130 434.4 0.0 2.9e-130 434.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAM18472.1 - 0.0069 15.0 0.0 0.2 10.2 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein SLT PF01464.15 GAM18473.1 - 5.2e-10 38.8 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 GAM18473.1 - 0.00071 19.5 4.2 0.0055 16.6 2.9 2.2 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.15 GAM18474.1 - 1.1e-08 34.6 0.0 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 GAM18474.1 - 8.9e-05 22.4 2.5 0.00055 19.9 1.8 1.9 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Pkinase PF00069.20 GAM18475.1 - 5.2e-42 143.7 0.0 8.4e-34 116.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18475.1 - 1.8e-28 99.3 0.0 7.9e-28 97.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.19 GAM18475.1 - 2e-07 30.9 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM18475.1 - 0.00017 21.6 0.0 0.00054 20.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM18475.1 - 0.00019 21.5 0.0 0.00058 19.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM18475.1 - 0.066 13.0 0.0 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FF PF01846.14 GAM18475.1 - 0.075 12.9 0.0 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 FF domain Acyl-CoA_dh_1 PF00441.19 GAM18476.1 - 1.4e-26 93.3 0.1 2.6e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM18476.1 - 2e-25 89.5 0.1 5e-25 88.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM18476.1 - 5.3e-20 70.6 0.0 1.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM18476.1 - 9.6e-08 32.3 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TIG PF01833.19 GAM18478.1 - 4.8e-19 68.1 74.7 9.8e-05 22.2 2.4 9.0 8 1 1 9 9 9 7 IPT/TIG domain DUF4448 PF14610.1 GAM18478.1 - 0.0014 18.1 0.1 0.0038 16.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ING PF12998.2 GAM18479.1 - 4.1e-23 81.6 3.6 6.4e-23 81.0 2.5 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 GAM18479.1 - 1.1e-09 37.8 7.5 1.8e-09 37.1 5.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 GAM18479.1 - 0.012 15.7 0.1 0.027 14.6 0.1 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain CASP_C PF08172.7 GAM18479.1 - 0.016 14.2 0.8 0.026 13.5 0.5 1.4 1 0 0 1 1 1 0 CASP C terminal DUF1313 PF07011.6 GAM18479.1 - 0.049 13.3 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) DUF1687 PF07955.6 GAM18479.1 - 0.086 12.8 0.7 0.36 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) zf-RING-like PF08746.6 GAM18479.1 - 0.096 12.7 2.5 0.18 11.8 1.7 1.5 1 0 0 1 1 1 0 RING-like domain Lectin_N PF03954.9 GAM18479.1 - 2.3 7.6 5.6 0.29 10.5 0.8 1.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain FlxA PF14282.1 GAM18479.1 - 4.6 7.2 7.0 0.3 11.0 1.0 1.9 2 0 0 2 2 2 0 FlxA-like protein AAA PF00004.24 GAM18480.1 - 2.2e-41 141.1 3.2 4.5e-40 136.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM18480.1 - 2.9e-07 30.2 0.7 3.1e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM18480.1 - 4.6e-06 26.7 0.1 0.0037 17.2 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 GAM18480.1 - 8.4e-05 22.5 0.8 0.00033 20.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAM18480.1 - 0.0001 21.4 0.2 0.00033 19.7 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM18480.1 - 0.00027 21.0 1.8 0.01 15.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM18480.1 - 0.00072 19.4 0.1 0.0035 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM18480.1 - 0.00097 19.9 0.2 0.0097 16.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 GAM18480.1 - 0.0011 18.2 0.0 0.0088 15.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 GAM18480.1 - 0.0024 16.8 0.0 0.0052 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 GAM18480.1 - 0.0027 16.8 0.1 0.012 14.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAM18480.1 - 0.0039 17.0 0.2 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM18480.1 - 0.0054 16.4 1.7 0.014 15.0 0.1 2.3 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 GAM18480.1 - 0.0063 15.9 0.1 0.016 14.6 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAM18480.1 - 0.014 14.5 0.7 0.056 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 GAM18480.1 - 0.016 14.6 0.8 0.41 10.0 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM18480.1 - 0.032 13.8 0.1 0.1 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 GAM18480.1 - 0.047 13.1 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 GAM18480.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 GAM18480.1 - 0.07 12.2 1.6 0.16 11.0 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.1 GAM18480.1 - 0.079 12.5 0.5 0.4 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.6 GAM18480.1 - 0.087 12.4 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAM18480.1 - 0.12 12.0 0.2 1.8 8.1 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 GAM18480.1 - 0.15 12.4 0.9 1.8 8.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAM18480.1 - 0.17 11.8 2.9 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain zf-met PF12874.2 GAM18481.1 - 6.1e-12 45.3 2.8 2e-06 27.8 0.3 3.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM18481.1 - 2.3e-07 30.7 6.0 0.00078 19.5 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM18481.1 - 1.3e-06 28.4 8.0 8.1e-05 22.6 1.1 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 GAM18481.1 - 0.0053 17.0 9.3 0.35 11.3 0.4 3.1 3 1 0 3 3 3 2 C2H2-type zinc finger DUF3449 PF11931.3 GAM18481.1 - 0.025 14.0 3.5 1.2 8.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) zf-U1 PF06220.7 GAM18481.1 - 0.051 13.1 5.5 0.081 12.4 0.2 2.5 2 1 0 2 2 2 0 U1 zinc finger DUF3106 PF11304.3 GAM18481.1 - 0.23 11.8 0.4 0.23 11.8 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3106) zf-C2H2 PF00096.21 GAM18481.1 - 0.52 10.7 5.4 8.4 6.9 0.1 3.1 2 2 0 2 2 2 0 Zinc finger, C2H2 type E6 PF00518.12 GAM18481.1 - 0.56 10.5 4.3 1.3 9.4 3.0 1.6 1 1 0 1 1 1 0 Early Protein (E6) Elf1 PF05129.8 GAM18481.1 - 2.8 7.7 6.1 10 5.9 1.3 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Pkinase PF00069.20 GAM18484.1 - 7.3e-56 189.1 0.0 9.2e-56 188.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18484.1 - 1.8e-22 79.6 0.0 2.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM18484.1 - 2.3e-05 23.5 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM18484.1 - 0.019 14.0 0.1 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM18484.1 - 0.019 14.6 0.1 0.044 13.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM18484.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 GAM18484.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4561 PF15120.1 GAM18485.1 - 0.08 12.4 0.2 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) Mnd1 PF03962.10 GAM18485.1 - 0.11 12.0 0.3 0.14 11.7 0.2 1.1 1 0 0 1 1 1 0 Mnd1 family adh_short PF00106.20 GAM18486.1 - 7.8e-26 90.9 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM18486.1 - 3.5e-16 59.7 0.0 4.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM18486.1 - 3.6e-06 26.7 0.0 5.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM18486.1 - 0.0051 15.9 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM18486.1 - 0.037 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding BCNT PF07572.7 GAM18486.1 - 0.18 11.7 0.6 0.34 10.8 0.4 1.4 1 0 0 1 1 1 0 Bucentaur or craniofacial development CENP-F_leu_zip PF10473.4 GAM18487.1 - 0.00033 20.5 9.3 0.0032 17.3 2.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.14 GAM18487.1 - 0.0015 16.4 2.5 0.0016 16.4 1.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IncA PF04156.9 GAM18487.1 - 0.0047 16.5 4.0 0.0052 16.4 2.0 1.5 1 1 1 2 2 2 1 IncA protein APG6 PF04111.7 GAM18487.1 - 0.0073 15.4 8.3 0.0092 15.0 5.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Syntaxin PF00804.20 GAM18487.1 - 0.014 15.5 0.8 0.014 15.5 0.6 2.2 2 0 0 2 2 2 0 Syntaxin Rhabdo_M1 PF03342.8 GAM18487.1 - 0.033 13.3 5.2 0.04 13.0 3.6 1.1 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) TerB-N PF13208.1 GAM18487.1 - 0.19 11.1 1.3 0.26 10.7 0.9 1.2 1 0 0 1 1 1 0 TerB-N BBP1_C PF15272.1 GAM18487.1 - 0.41 10.1 11.9 0.16 11.5 4.4 2.3 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal FlaC_arch PF05377.6 GAM18487.1 - 0.57 10.1 14.1 1.7 8.5 0.2 3.5 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) Lip_prot_lig_C PF10437.4 GAM18487.1 - 0.92 9.2 4.3 0.79 9.4 0.2 2.2 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus TBPIP PF07106.8 GAM18487.1 - 1.1 8.8 10.5 0.21 11.1 3.4 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-K PF11802.3 GAM18487.1 - 1.2 8.3 8.2 1.5 7.9 5.7 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF724 PF05266.9 GAM18487.1 - 1.8 8.1 7.2 4 7.0 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Med21 PF11221.3 GAM18487.1 - 2.2 8.2 6.6 8.1 6.4 0.5 2.5 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Phlebovirus_NSM PF07246.6 GAM18487.1 - 2.7 7.0 7.1 3.4 6.7 4.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF972 PF06156.8 GAM18487.1 - 3.1 8.1 8.7 1.4 9.2 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Transposase_22 PF02994.9 GAM18487.1 - 4.2 5.7 10.2 0.64 8.4 3.4 1.8 1 1 1 2 2 2 0 L1 transposable element Sec8_exocyst PF04048.9 GAM18489.1 - 1.9e-17 63.2 0.4 1.9e-17 63.2 0.3 2.2 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.4 GAM18489.1 - 0.0057 16.4 2.1 0.0062 16.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) CRAL_TRIO PF00650.15 GAM18490.1 - 1.7e-32 112.1 0.0 2.3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM18490.1 - 7.4e-08 32.4 0.1 1.9e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NDK PF00334.14 GAM18491.1 - 1.1e-51 174.1 0.0 1.4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_TM PF02921.9 GAM18491.1 - 0.13 12.4 1.8 0.32 11.2 1.2 1.6 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region EF-hand_6 PF13405.1 GAM18492.1 - 6.2e-10 38.1 0.0 4.3e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 GAM18492.1 - 1.2e-09 36.7 0.0 0.00013 20.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 GAM18492.1 - 9.4e-09 34.7 0.0 5.4e-05 22.7 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 GAM18492.1 - 6.6e-08 32.5 0.1 9.5e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM18492.1 - 1.9e-07 30.1 0.0 0.00023 20.3 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 GAM18492.1 - 0.023 14.3 0.7 0.19 11.4 0.2 2.0 1 1 1 2 2 2 0 EF hand TLD PF07534.11 GAM18493.1 - 2.4e-33 115.0 0.3 5e-33 114.0 0.2 1.5 1 0 0 1 1 1 1 TLD LysM PF01476.15 GAM18493.1 - 1e-06 28.5 0.1 3.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 LysM domain GRAM PF02893.15 GAM18493.1 - 0.0005 19.5 0.1 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Tweety PF04906.8 GAM18494.1 - 3.5e-08 32.2 5.6 3.8e-06 25.5 3.5 3.0 2 1 0 2 2 2 1 Tweety FA_desaturase PF00487.19 GAM18494.1 - 0.0033 16.9 0.3 1.1 8.6 0.1 2.2 2 0 0 2 2 2 2 Fatty acid desaturase Baculo_helicase PF04735.7 GAM18494.1 - 0.067 10.5 0.2 0.1 9.9 0.1 1.2 1 0 0 1 1 1 0 Baculovirus DNA helicase DUF2517 PF10725.4 GAM18494.1 - 6.5 6.5 6.0 14 5.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2517) LRR_4 PF12799.2 GAM18495.1 - 0.016 14.8 13.6 0.067 12.8 1.3 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 GAM18495.1 - 0.23 11.8 8.6 10 6.8 0.1 6.0 5 1 0 5 5 5 0 Leucine rich repeat DUF2207 PF09972.4 GAM18496.1 - 6.3e-06 25.0 0.7 0.0011 17.5 0.1 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) Tweety PF04906.8 GAM18496.1 - 7.1e-06 24.6 13.6 0.00018 20.0 9.4 2.4 1 1 0 1 1 1 1 Tweety ABC2_membrane_2 PF12679.2 GAM18496.1 - 0.023 13.5 4.0 0.056 12.2 0.1 2.8 3 0 0 3 3 3 0 ABC-2 family transporter protein Pkinase PF00069.20 GAM18498.1 - 4.9e-54 183.1 0.0 6.6e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18498.1 - 1.2e-16 60.5 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM18498.1 - 5.6e-06 26.2 0.1 0.00015 21.5 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM18498.1 - 0.0028 16.6 0.0 0.0056 15.6 0.0 1.4 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.11 GAM18498.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Mito_carr PF00153.22 GAM18499.1 - 1.3e-68 226.7 1.5 3.9e-24 84.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3357 PF11837.3 GAM18500.1 - 0.0073 16.1 0.4 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) Baculo_11_kDa PF06143.6 GAM18500.1 - 0.0099 15.2 0.7 0.017 14.5 0.5 1.3 1 0 0 1 1 1 1 Baculovirus 11 kDa family EphA2_TM PF14575.1 GAM18500.1 - 0.014 15.7 0.2 0.033 14.5 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1564 PF07600.6 GAM18500.1 - 0.025 13.9 0.2 0.036 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Ly49 PF08391.5 GAM18500.1 - 0.026 14.6 7.4 0.1 12.7 5.3 1.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF106 PF01956.11 GAM18500.1 - 0.038 13.5 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Claudin_2 PF13903.1 GAM18500.1 - 0.052 13.2 0.3 0.077 12.6 0.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Conotoxin PF02950.12 GAM18500.1 - 0.054 14.3 0.2 0.054 14.3 0.1 2.7 3 0 0 3 3 3 0 Conotoxin DUF2232 PF09991.4 GAM18500.1 - 0.055 12.4 1.3 0.071 12.0 0.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Protocadherin PF08374.6 GAM18500.1 - 0.059 13.0 1.2 0.081 12.5 0.7 1.5 1 1 0 1 1 1 0 Protocadherin Chordopox_A13L PF05961.6 GAM18500.1 - 0.065 13.1 0.2 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SIT PF15330.1 GAM18500.1 - 0.071 13.2 4.3 0.04 14.0 1.3 1.8 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT YfhO PF09586.5 GAM18500.1 - 0.15 10.0 0.7 0.18 9.7 0.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF843 PF05814.6 GAM18500.1 - 0.22 11.3 2.3 0.35 10.6 1.6 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF848 PF05852.6 GAM18500.1 - 0.41 10.4 8.0 0.59 9.9 5.6 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Bap31 PF05529.7 GAM18500.1 - 0.42 10.0 5.0 0.66 9.4 3.4 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Serinc PF03348.10 GAM18500.1 - 0.43 9.2 2.8 0.16 10.6 0.6 1.4 1 1 1 2 2 2 0 Serine incorporator (Serinc) Med3 PF11593.3 GAM18500.1 - 0.45 9.7 6.9 0.74 8.9 4.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SID-1_RNA_chan PF13965.1 GAM18500.1 - 1.1 7.3 4.1 0.54 8.3 1.8 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM51 PF15345.1 GAM18500.1 - 7.7 6.1 6.8 22 4.6 4.7 1.8 1 1 0 1 1 1 0 Transmembrane protein 51 DUF1510 PF07423.6 GAM18500.1 - 8.8 5.6 18.9 1.5 8.1 8.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Ribosomal_L18e PF00828.14 GAM18501.1 - 3.2e-13 50.1 3.4 5.6e-13 49.3 1.1 1.9 1 1 1 2 2 2 1 Ribosomal protein L18e/L15 RTX_C PF08339.5 GAM18502.1 - 0.042 13.5 0.5 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 RTX C-terminal domain Folate_carrier PF01770.13 GAM18503.1 - 2.5e-88 296.3 37.3 3.3e-48 164.2 11.6 2.1 1 1 1 2 2 2 2 Reduced folate carrier MFS_1 PF07690.11 GAM18503.1 - 1.4e-10 40.4 29.1 1.4e-10 40.4 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily FUSC PF04632.7 GAM18503.1 - 0.073 11.4 1.3 0.12 10.7 0.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C2H2_jaz PF12171.3 GAM18504.1 - 1.3e-05 25.2 2.8 1.3e-05 25.2 2.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM18504.1 - 0.00031 20.8 3.1 0.00031 20.8 2.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FHA PF00498.21 GAM18505.1 - 5.2e-17 61.7 0.4 1.1e-15 57.4 0.1 2.5 2 0 0 2 2 2 1 FHA domain zf-C3HC4_3 PF13920.1 GAM18505.1 - 0.00022 20.7 12.4 0.00022 20.7 8.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM18505.1 - 0.00023 20.9 16.7 0.00023 20.9 11.6 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAM18505.1 - 0.0013 18.3 17.7 0.0013 18.3 12.3 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM18505.1 - 0.0014 18.5 17.9 0.0014 18.5 12.4 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAM18505.1 - 0.025 14.3 13.5 0.041 13.6 4.2 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 GAM18505.1 - 5.4 6.8 31.4 0.093 12.4 10.9 3.4 2 1 0 2 2 2 0 zinc-RING finger domain RhoGEF PF00621.15 GAM18506.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain Pkinase_Tyr PF07714.12 GAM18507.1 - 1.4e-52 178.3 0.0 2.1e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM18507.1 - 1.2e-48 165.5 0.0 2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Miro PF08477.8 GAM18507.1 - 7e-17 62.0 0.0 2e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM18507.1 - 2.5e-15 56.2 0.2 5.2e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM18507.1 - 3.7e-11 42.5 0.0 6.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_4 PF12799.2 GAM18507.1 - 1.4e-07 30.9 4.6 0.00028 20.4 2.6 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18507.1 - 7.6e-07 28.7 8.7 9.2e-05 22.1 0.3 2.1 1 1 1 2 2 2 2 Leucine rich repeat Gtr1_RagA PF04670.7 GAM18507.1 - 5.9e-05 22.3 0.2 0.0002 20.5 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM18507.1 - 0.00026 20.9 0.0 0.00075 19.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAM18507.1 - 0.00045 20.5 1.4 0.0016 18.7 0.8 2.0 1 1 1 2 2 2 1 ABC transporter LRR_1 PF00560.28 GAM18507.1 - 0.0014 18.3 3.4 0.6 10.3 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat DUF258 PF03193.11 GAM18507.1 - 0.006 15.7 0.2 0.014 14.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAM18507.1 - 0.0088 15.4 0.1 0.036 13.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAM18507.1 - 0.018 14.5 0.6 0.057 12.8 0.3 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 GAM18507.1 - 0.019 13.9 0.5 0.041 12.8 0.4 1.4 1 0 0 1 1 1 0 Septin Zeta_toxin PF06414.7 GAM18507.1 - 0.032 13.3 0.3 0.73 8.8 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Ank_2 PF12796.2 GAM18507.1 - 0.15 12.3 0.4 0.36 11.2 0.3 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) LRR_7 PF13504.1 GAM18507.1 - 0.77 10.2 5.6 21 5.8 0.0 4.4 4 0 0 4 4 3 0 Leucine rich repeat DUF605 PF04652.11 GAM18507.1 - 3.3 7.0 12.2 5.4 6.3 8.4 1.2 1 0 0 1 1 1 0 Vta1 like MORN PF02493.15 GAM18508.1 - 1.7e-12 46.2 16.5 0.0021 17.6 0.1 6.3 6 0 0 6 6 6 5 MORN repeat SET PF00856.23 GAM18508.1 - 7.5e-06 26.3 0.4 7.5e-06 26.3 0.3 2.7 2 1 0 2 2 2 1 SET domain FNIP PF05725.7 GAM18509.1 - 3.3e-43 145.3 33.6 3.1e-10 39.8 0.7 7.5 7 0 0 7 7 7 7 FNIP Repeat FSH1 PF03959.8 GAM18510.1 - 1.1e-48 165.5 0.3 2.6e-47 160.9 0.2 2.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 GAM18510.1 - 0.00058 19.6 0.0 0.0012 18.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM18510.1 - 0.0035 16.9 0.1 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM18510.1 - 0.028 14.2 0.0 0.52 10.1 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_24 PF13578.1 GAM18510.1 - 0.057 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Secretin_N_2 PF07655.8 GAM18510.1 - 1.5 9.2 12.8 3.1 8.2 8.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain SK_channel PF03530.9 GAM18511.1 - 0.0094 15.7 1.1 0.046 13.5 0.8 2.2 1 1 0 1 1 1 1 Calcium-activated SK potassium channel DUF4395 PF14340.1 GAM18511.1 - 0.15 12.1 2.9 1.6 8.8 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) PAT1 PF09770.4 GAM18511.1 - 1.1 7.3 37.2 1.5 6.9 25.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pmp3 PF01679.12 GAM18512.1 - 1.5e-22 79.0 7.1 1.6e-22 78.9 4.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF3099 PF11298.3 GAM18512.1 - 0.41 10.4 1.6 0.76 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) Inhibitor_I29 PF08246.7 GAM18513.1 - 0.46 10.8 3.3 17 5.7 0.2 2.5 2 1 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Mod_r PF07200.8 GAM18514.1 - 5e-21 75.1 21.5 5e-21 75.1 14.9 1.7 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.4 GAM18514.1 - 0.39 9.6 7.7 0.66 8.8 5.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_LMP2 PF07415.6 GAM18514.1 - 2.8 6.4 6.6 4.1 5.8 4.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Bap31 PF05529.7 GAM18514.1 - 5 6.5 14.7 0.86 9.0 2.8 2.5 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like DUF2461 PF09365.5 GAM18516.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) Voltage_CLC PF00654.15 GAM18517.1 - 2.1e-78 263.8 20.4 2.1e-78 263.8 14.2 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 GAM18517.1 - 2e-10 40.3 2.6 0.0001 21.9 0.0 3.0 3 0 0 3 3 3 2 CBS domain Sigma70_r1_1 PF03979.9 GAM18517.1 - 0.0076 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 Phage_holin_3 PF05106.7 GAM18517.1 - 4.8 7.2 11.8 2.8 7.9 0.7 4.2 4 0 0 4 4 4 0 Phage holin family (Lysis protein S) GST_N PF02798.15 GAM18518.1 - 3.6e-09 36.6 0.0 8e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM18518.1 - 3.8e-07 29.9 0.0 1.5e-06 28.0 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM18518.1 - 0.00017 22.0 0.0 0.00025 21.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM18518.1 - 0.0035 17.5 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM18518.1 - 0.0064 16.3 0.1 0.014 15.2 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 GAM18519.1 - 1.8e-46 154.3 8.0 1.3e-10 40.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 GAM18519.1 - 1.3e-26 93.5 1.2 1.3e-26 93.5 0.8 2.5 2 0 0 2 2 2 1 Striatin family Nup160 PF11715.3 GAM18519.1 - 3.2e-06 25.5 2.9 0.0081 14.3 0.2 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM18519.1 - 4.6e-05 22.3 0.8 0.025 13.3 0.6 3.5 2 1 1 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 GAM18519.1 - 0.022 14.2 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain Sen15 PF09631.5 GAM18519.1 - 0.094 12.9 1.4 12 6.1 0.0 4.0 4 0 0 4 4 4 0 Sen15 protein IncA PF04156.9 GAM18519.1 - 8.1 5.9 10.5 8 6.0 0.3 2.4 2 0 0 2 2 2 0 IncA protein Mak10 PF04112.8 GAM18520.1 - 5.2e-21 74.5 0.1 1.6e-20 72.9 0.0 1.9 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FliL PF03748.9 GAM18520.1 - 0.0058 16.5 0.1 0.021 14.7 0.0 2.0 1 1 0 1 1 1 1 Flagellar basal body-associated protein FliL EST1 PF10374.4 GAM18520.1 - 0.23 11.4 4.6 0.62 10.0 0.7 2.6 2 0 0 2 2 2 0 Telomerase activating protein Est1 DUF3987 PF13148.1 GAM18520.1 - 0.24 9.9 6.5 0.49 8.9 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1325 PF07039.6 GAM18521.1 - 2.8e-32 111.0 1.2 5e-32 110.2 0.8 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 GAM18521.1 - 0.00061 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) MIP-T3 PF10243.4 GAM18521.1 - 4.2 5.7 38.3 6.1 5.1 26.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SWIM PF04434.12 GAM18523.1 - 0.00027 20.3 2.4 0.00048 19.5 1.6 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF3930 PF13067.1 GAM18523.1 - 0.27 11.0 0.4 1.4 8.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) GRAM PF02893.15 GAM18524.1 - 7.8e-25 86.1 3.5 4.3e-13 48.5 0.1 2.4 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.3 GAM18524.1 - 2e-05 24.3 1.0 0.047 13.4 0.2 2.5 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 GAM18524.1 - 6.9e-05 23.0 5.6 0.01 16.0 0.2 2.3 2 0 0 2 2 2 2 Bacterial PH domain DUF2113 PF09886.4 GAM18524.1 - 0.00015 20.9 0.9 0.25 10.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2113) DUF3124 PF11322.3 GAM18524.1 - 0.041 13.7 0.8 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3124) Rtt106 PF08512.7 GAM18524.1 - 0.064 13.2 1.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Exo_endo_phos PF03372.18 GAM18525.1 - 9.1e-33 114.2 0.1 1.3e-32 113.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 GAM18525.1 - 1.2e-25 89.9 0.0 2.5e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Patatin PF01734.17 GAM18527.1 - 1.3e-19 70.9 0.0 1.3e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase UPF0449 PF15136.1 GAM18527.1 - 0.029 14.5 0.2 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Dicty_REP PF05086.7 GAM18527.1 - 2.1 5.9 10.6 3.7 5.1 7.4 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Aha1_N PF09229.6 GAM18528.1 - 3.4e-29 101.4 1.5 6.1e-29 100.5 1.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 GAM18528.1 - 7.7e-14 51.8 0.1 1.8e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein INCENP_ARK-bind PF03941.10 GAM18529.1 - 1.6e-08 34.2 0.2 1.6e-08 34.2 0.1 4.1 4 0 0 4 4 4 1 Inner centromere protein, ARK binding region Daxx PF03344.10 GAM18529.1 - 2.2e-05 23.1 11.8 2.2e-05 23.1 8.2 4.0 2 1 2 4 4 4 1 Daxx Family Exo_endo_phos PF03372.18 GAM18530.1 - 3.3e-17 63.2 0.0 4.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Guanylate_cyc PF00211.15 GAM18531.1 - 2.5e-77 258.4 2.0 3.4e-40 137.3 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 GAM18531.1 - 0.016 14.4 8.4 0.11 11.7 0.0 2.8 3 0 0 3 3 3 0 Heme NO binding associated Pex14_N PF04695.8 GAM18531.1 - 0.69 9.9 7.1 2 8.4 4.9 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2681 PF10883.3 GAM18531.1 - 1.4 9.1 9.8 15 5.8 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ECH PF00378.15 GAM18532.1 - 1.3e-26 93.2 0.0 1.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAM18532.1 - 1.3e-21 76.8 0.0 4e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_C26 PF07722.8 GAM18533.1 - 2e-35 122.2 0.0 2.6e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 GAM18533.1 - 8.7e-08 31.8 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PS_pyruv_trans PF04230.8 GAM18533.1 - 0.063 12.9 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Trs65 PF12735.2 GAM18534.1 - 1.6e-12 47.3 16.6 1.6e-12 47.3 11.5 4.5 2 2 0 2 2 2 1 TRAPP trafficking subunit Trs65 A2M PF00207.17 GAM18534.1 - 0.01 15.3 0.1 0.036 13.6 0.1 2.0 1 0 0 1 1 1 0 Alpha-2-macroglobulin family Cpn60_TCP1 PF00118.19 GAM18535.1 - 0.0006 18.5 0.1 0.0007 18.3 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Katanin_con80 PF13925.1 GAM18535.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 con80 domain of Katanin Ank_2 PF12796.2 GAM18536.1 - 1.1e-18 67.3 0.1 2.6e-07 30.8 0.0 4.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM18536.1 - 1.1e-18 66.7 0.8 0.0038 17.4 0.0 6.8 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM18536.1 - 9.5e-14 51.4 0.2 0.002 18.5 0.0 5.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18536.1 - 5.6e-12 44.6 0.1 6.1 7.3 0.0 7.3 7 1 1 8 8 8 4 Ankyrin repeat Ank PF00023.25 GAM18536.1 - 4.6e-11 41.9 0.5 3.2 7.7 0.0 7.3 4 1 4 8 8 8 4 Ankyrin repeat LCAT PF02450.10 GAM18537.1 - 4.6e-43 147.6 0.1 6e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 GAM18537.1 - 1.2e-05 25.0 0.0 6e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAM18537.1 - 0.00061 19.7 0.0 0.0016 18.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.7 GAM18537.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 GAM18537.1 - 0.027 14.0 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase DUF676 PF05057.9 GAM18537.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAM18537.1 - 0.056 13.1 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Malectin PF11721.3 GAM18538.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Di-glucose binding within endoplasmic reticulum Flu_C_NS1 PF03506.8 GAM18538.1 - 0.11 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) F-box PF00646.28 GAM18539.1 - 0.0047 16.5 0.5 0.02 14.5 0.3 2.2 1 0 0 1 1 1 1 F-box domain Bax1-I PF01027.15 GAM18540.1 - 7.8e-27 94.2 27.1 9.3e-27 93.9 18.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_A14 PF05767.7 GAM18540.1 - 0.0026 17.6 1.0 0.0026 17.6 0.7 2.4 2 2 0 2 2 2 1 Poxvirus virion envelope protein A14 Archaeal_AmoA PF12942.2 GAM18540.1 - 0.014 15.1 3.9 0.083 12.6 0.2 2.1 1 1 1 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) PTS_EIIC_2 PF13303.1 GAM18540.1 - 0.091 11.5 10.1 0.052 12.3 4.4 1.9 1 1 0 2 2 2 0 Phosphotransferase system, EIIC DUF4293 PF14126.1 GAM18540.1 - 2.6 7.9 19.4 0.55 10.1 5.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF3353 PF11833.3 GAM18540.1 - 10 5.5 9.8 1.3 8.4 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) IncA PF04156.9 GAM18541.1 - 4.8 6.7 10.6 9.2 5.8 7.3 1.5 1 0 0 1 1 1 0 IncA protein DUF456 PF04306.8 GAM18542.1 - 0.38 10.7 3.5 0.7 9.9 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF456) P12 PF12669.2 GAM18542.1 - 1.3 9.3 8.0 22 5.3 0.0 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family ATP_synt_H PF05493.8 GAM18543.1 - 1.2e-14 54.0 6.7 1.6e-14 53.6 4.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H TRAM_LAG1_CLN8 PF03798.11 GAM18544.1 - 1.9e-20 73.2 11.5 1.9e-20 73.2 8.0 1.6 2 0 0 2 2 2 1 TLC domain Ank_2 PF12796.2 GAM18545.1 - 1.7e-53 178.9 27.8 2.4e-10 40.6 0.1 6.7 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM18545.1 - 1.3e-33 114.2 24.7 0.0047 17.1 0.3 14.0 3 2 11 14 14 14 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM18545.1 - 1.1e-32 111.8 18.1 0.00017 22.0 0.1 9.3 5 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18545.1 - 7e-27 90.8 19.8 1.6 9.2 0.0 14.7 6 5 9 15 15 15 9 Ankyrin repeat Ank PF00023.25 GAM18545.1 - 8.8e-23 78.9 20.5 0.22 11.4 0.0 13.9 13 2 2 15 15 15 7 Ankyrin repeat DUF2493 PF10686.4 GAM18545.1 - 0.005 16.3 0.4 11 5.6 0.0 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF2493) Rbsn PF11464.3 GAM18545.1 - 0.025 14.1 2.0 78 2.9 0.0 5.9 6 1 1 7 7 7 0 Rabenosyn Rab binding domain Pkinase PF00069.20 GAM18546.1 - 1.3e-48 165.3 0.4 3.3e-48 164.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18546.1 - 9.6e-38 129.7 0.0 1.8e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGEF PF00621.15 GAM18546.1 - 2.8e-37 128.3 0.7 2.8e-37 128.3 0.5 2.3 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM18546.1 - 0.0017 18.5 0.0 0.005 17.0 0.0 1.9 1 0 0 1 1 1 1 PH domain APH PF01636.18 GAM18546.1 - 0.0067 16.1 1.6 0.83 9.3 0.0 3.0 2 1 0 3 3 3 1 Phosphotransferase enzyme family IncA PF04156.9 GAM18546.1 - 0.34 10.4 17.3 1.6 8.2 10.7 2.4 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 GAM18546.1 - 0.79 8.0 6.5 2.2 6.5 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 GAM18546.1 - 1.1 8.2 14.7 3.3 6.6 10.2 1.8 1 0 0 1 1 1 0 Autophagy protein Apg6 TEX13 PF15186.1 GAM18546.1 - 4 6.9 14.0 2 8.0 7.8 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF4175 PF13779.1 GAM18546.1 - 5.4 4.5 20.6 8.7 3.9 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ADH_zinc_N PF00107.21 GAM18547.1 - 6.6e-24 83.9 0.0 1.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM18547.1 - 8e-13 48.1 0.0 7e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM18547.1 - 0.00016 22.5 0.0 0.0012 19.7 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAM18547.1 - 0.088 12.3 0.2 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dynactin_p22 PF07426.6 GAM18548.1 - 0.0039 16.4 1.7 0.0058 15.9 0.2 1.8 2 0 0 2 2 2 1 Dynactin subunit p22 TFIID_20kDa PF03847.8 GAM18548.1 - 0.23 11.7 2.7 0.74 10.1 0.1 2.6 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A FH2 PF02181.18 GAM18549.1 - 2.3e-79 266.9 1.3 2.3e-79 266.9 0.9 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain 4HBT_3 PF13622.1 GAM18549.1 - 0.047 13.4 1.6 0.1 12.2 1.1 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily Totivirus_coat PF05518.6 GAM18549.1 - 1.7 6.3 5.9 2.8 5.6 4.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein bZIP_2 PF07716.10 GAM18550.1 - 4.3e-08 32.8 6.8 1.1e-07 31.5 4.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM18550.1 - 3.2e-07 30.2 4.0 3.2e-07 30.2 2.8 2.5 2 0 0 2 2 2 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 GAM18550.1 - 0.04 13.7 0.2 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF972 PF06156.8 GAM18550.1 - 0.2 12.0 3.2 13 6.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pro_isomerase PF00160.16 GAM18552.1 - 1.2e-45 155.5 1.4 1.4e-45 155.3 1.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FNIP PF05725.7 GAM18553.1 - 1.8e-63 210.2 47.3 2e-12 46.8 0.8 10.2 6 2 3 10 10 10 8 FNIP Repeat MerC PF03203.9 GAM18553.1 - 0.098 13.0 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein Ank_2 PF12796.2 GAM18554.1 - 1.4e-38 131.0 20.5 3.3e-09 36.9 1.2 6.1 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM18554.1 - 1.2e-30 105.3 19.4 0.00021 21.7 0.0 9.1 8 2 1 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM18554.1 - 1.3e-28 98.3 24.7 0.0047 17.1 0.3 13.7 2 2 13 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18554.1 - 6e-23 78.6 29.2 0.14 12.4 0.1 14.3 7 6 9 16 16 16 7 Ankyrin repeat Ank PF00023.25 GAM18554.1 - 9.3e-22 75.6 26.0 0.74 9.7 1.4 14.2 14 1 1 15 15 15 9 Ankyrin repeat DUF1707 PF08044.6 GAM18554.1 - 0.0026 17.4 1.2 5.4 6.8 0.1 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1707) zf-4CXXC_R1 PF10497.4 GAM18554.1 - 0.012 15.7 0.4 82 3.4 0.0 4.8 4 1 0 5 5 5 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF1450 PF07293.6 GAM18554.1 - 0.053 13.5 0.6 8 6.5 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1450) FERM_M PF00373.13 GAM18554.1 - 0.093 12.9 0.6 7.5 6.7 0.1 2.4 1 1 1 2 2 2 0 FERM central domain DUF2462 PF09495.5 GAM18554.1 - 0.23 12.2 0.0 3.3e+02 2.0 0.0 5.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2462) Chitin_bind_3 PF03067.10 GAM18556.1 - 2.8e-27 96.1 0.1 3.5e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Chitin binding domain WD40 PF00400.27 GAM18557.1 - 5.9e-19 67.1 0.9 0.00029 20.6 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Lactonase PF10282.4 GAM18557.1 - 0.0074 15.3 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Orn_Arg_deC_N PF02784.11 GAM18558.1 - 1.9e-39 135.3 0.0 2.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAM18558.1 - 8.7e-15 54.4 0.0 1.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ala_racemase_N PF01168.15 GAM18558.1 - 0.094 12.2 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 Alanine racemase, N-terminal domain Claudin_2 PF13903.1 GAM18559.1 - 6.2e-05 22.7 2.9 0.0022 17.6 1.5 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Bac_rhodopsin PF01036.13 GAM18559.1 - 0.0061 15.8 0.4 0.0061 15.8 0.3 1.7 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein PMP22_Claudin PF00822.15 GAM18559.1 - 0.021 14.4 0.7 0.021 14.4 0.5 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF1772 PF08592.6 GAM18559.1 - 0.065 12.9 5.7 0.26 11.0 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) DUF2569 PF10754.4 GAM18559.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) DUF4381 PF14316.1 GAM18559.1 - 0.18 11.9 0.7 2.7 8.0 0.0 2.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.1 GAM18559.1 - 3.1 8.2 7.3 13 6.2 0.0 3.2 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain CbiQ PF02361.11 GAM18559.1 - 6.5 6.2 7.9 0.26 10.8 1.7 1.4 2 0 0 2 2 2 0 Cobalt transport protein Kelch_4 PF13418.1 GAM18560.1 - 1e-06 28.3 2.4 0.0016 18.1 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM18560.1 - 1.2e-05 25.2 4.3 0.044 13.9 0.1 3.4 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 GAM18560.1 - 6.5e-05 22.3 4.7 0.01 15.3 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM18560.1 - 0.0004 20.0 0.4 0.52 10.1 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM18560.1 - 0.00043 20.1 2.4 0.14 12.1 0.3 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 GAM18560.1 - 0.0018 18.3 1.7 0.42 10.8 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain SHS2_Rpb7-N PF03876.12 GAM18561.1 - 5.4e-14 52.0 0.0 9.5e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 GAM18561.1 - 9.2e-12 44.8 1.1 1.2e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 GAM18561.1 - 0.0013 18.8 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ion_trans PF00520.26 GAM18562.1 - 1.8e-05 24.0 5.3 8.8e-05 21.8 2.2 2.2 2 0 0 2 2 2 2 Ion transport protein Saccharop_dh PF03435.13 GAM18563.1 - 5e-85 285.7 0.0 6.7e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 GAM18563.1 - 8.5e-28 97.0 0.1 3.4e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 GAM18563.1 - 3.2e-25 88.6 0.0 1.5e-24 86.4 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 GAM18563.1 - 2.9e-05 24.1 0.1 7.4e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAM18563.1 - 0.003 17.5 0.1 0.0069 16.4 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 GAM18563.1 - 0.0031 17.4 0.2 0.0079 16.1 0.2 1.7 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 GAM18563.1 - 0.006 16.5 0.2 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 GAM18563.1 - 0.015 15.8 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 GAM18563.1 - 0.03 14.6 0.1 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ThiF PF00899.16 GAM18563.1 - 0.03 14.1 0.0 0.74 9.6 0.0 2.5 1 1 1 2 2 2 0 ThiF family DUF1473 PF07341.6 GAM18563.1 - 0.032 13.7 0.2 0.088 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) UCH PF00443.24 GAM18565.1 - 5.3e-42 143.7 19.0 5.3e-42 143.7 13.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM18565.1 - 6.8e-15 55.2 16.6 6.8e-15 55.2 11.5 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Cyt-b5 PF00173.23 GAM18566.1 - 3.4e-21 74.8 0.1 6.6e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 GAM18566.1 - 5.8e-07 29.9 17.8 5.8e-07 29.9 12.3 1.8 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily ACOX PF01756.14 GAM18567.1 - 9.7e-23 80.5 0.0 1.7e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAM18567.1 - 1.6e-12 46.7 1.1 2.9e-12 45.9 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM18567.1 - 3.1e-10 40.3 0.3 5.4e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3963 PF13124.1 GAM18567.1 - 0.051 13.3 0.5 3.7 7.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) Acyl-CoA_ox_N PF14749.1 GAM18567.1 - 0.089 13.0 0.1 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal 2OG-FeII_Oxy_3 PF13640.1 GAM18569.1 - 1.3e-12 48.0 0.0 3.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.14 GAM18569.1 - 1.5e-10 40.0 0.1 6.2e-09 34.7 0.1 2.1 1 1 0 1 1 1 1 Actin 2OG-FeII_Oxy_4 PF13661.1 GAM18569.1 - 0.00017 21.1 0.1 0.00038 20.0 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 GAM18569.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box-like PP2C PF00481.16 GAM18570.1 - 4.4e-58 196.6 0.0 7.3e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 GAM18570.1 - 2.2e-44 148.4 78.5 3.9e-07 29.5 0.2 12.3 6 3 8 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18570.1 - 8e-41 137.6 72.0 2.7e-08 33.4 4.3 10.1 6 3 5 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 GAM18570.1 - 3.1e-32 105.6 58.9 0.2 11.7 0.0 19.4 19 0 0 19 19 19 11 Leucine Rich Repeat LRR_7 PF13504.1 GAM18570.1 - 3.8e-19 65.3 67.4 0.041 14.0 0.2 18.5 18 0 0 18 18 18 7 Leucine rich repeat LRR_6 PF13516.1 GAM18570.1 - 2.9e-10 39.1 70.0 0.11 12.5 0.1 16.2 17 0 0 17 17 17 5 Leucine Rich repeat PP2C_2 PF13672.1 GAM18570.1 - 2.2e-07 30.5 0.0 4.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.1 GAM18570.1 - 7.3e-07 28.9 13.9 0.0016 18.0 0.5 4.3 4 0 0 4 4 4 3 Leucine-rich repeat Alpha_L_fucos PF01120.12 GAM18571.1 - 1e-115 386.3 1.7 1.3e-115 386.0 1.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase 7tm_2 PF00002.19 GAM18572.1 - 1.4e-05 24.2 15.1 2.5e-05 23.4 10.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.12 GAM18572.1 - 0.00042 19.2 19.9 0.00055 18.8 13.8 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 GAM18573.1 - 1.5e-07 30.6 13.8 2.6e-07 29.8 9.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM18573.1 - 1.7e-07 30.6 15.4 2.7e-07 29.9 10.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) zf-DHHC PF01529.15 GAM18573.1 - 0.0074 15.7 5.0 0.0074 15.7 3.5 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 GAM18573.1 - 0.011 15.2 8.6 0.22 11.0 2.5 2.4 1 1 1 2 2 2 0 Yip1 domain LRR_8 PF13855.1 GAM18574.1 - 9.8e-10 38.0 21.8 0.00033 20.3 0.5 4.7 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 GAM18574.1 - 1.8e-05 24.2 26.6 0.002 17.6 1.0 5.4 4 3 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM18574.1 - 3.4e-05 23.4 14.5 3.2 8.0 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 GAM18574.1 - 0.065 13.4 21.8 3.8 8.1 0.1 7.3 7 1 1 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 GAM18574.1 - 0.2 11.8 22.1 0.53 10.5 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat CLU PF13236.1 GAM18575.1 - 1.1e-51 175.3 0.0 2.3e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM18575.1 - 7.5e-13 48.7 0.1 7.5e-13 48.7 0.1 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 LRR_4 PF12799.2 GAM18575.1 - 0.0099 15.4 4.2 1.8 8.3 0.2 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) TruB_N PF01509.13 GAM18575.1 - 0.059 13.5 1.8 0.16 12.1 1.2 1.7 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) LRR_8 PF13855.1 GAM18575.1 - 0.55 10.0 9.5 6.5 6.5 2.3 3.5 2 1 0 2 2 2 0 Leucine rich repeat CLU PF13236.1 GAM18576.1 - 2.3e-52 177.6 0.0 3.7e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM18576.1 - 2.2e-08 34.2 0.0 6.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.1 GAM18576.1 - 0.0002 21.0 10.0 16 5.9 0.0 8.8 8 1 1 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.28 GAM18576.1 - 0.098 12.7 6.0 1.5 9.0 0.1 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat TBPIP PF07106.8 GAM18577.1 - 1.9e-30 105.6 8.7 4.2e-30 104.5 6.0 1.6 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 GAM18577.1 - 4.9e-06 26.3 11.2 9.4e-06 25.4 7.4 1.8 1 1 0 1 1 1 1 Mnd1 family COPI_C PF06957.6 GAM18577.1 - 0.0051 15.3 1.0 0.0083 14.7 0.3 1.5 1 1 1 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus Phage_GP20 PF06810.6 GAM18577.1 - 0.028 13.8 13.5 0.043 13.2 6.7 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 GAM18577.1 - 0.045 13.9 3.4 0.11 12.7 2.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein PhaP_Bmeg PF09602.5 GAM18577.1 - 0.11 12.2 7.9 0.22 11.3 5.4 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF919 PF06034.6 GAM18577.1 - 0.13 11.9 2.3 0.33 10.6 1.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Seryl_tRNA_N PF02403.17 GAM18577.1 - 0.22 11.5 17.9 0.093 12.7 6.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.13 GAM18577.1 - 0.24 11.1 7.5 0.55 9.9 1.7 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF342 PF03961.8 GAM18577.1 - 0.31 9.3 7.4 0.44 8.9 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 GAM18577.1 - 0.36 9.7 5.3 0.49 9.2 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) STN1_2 PF09170.5 GAM18577.1 - 0.39 10.4 0.1 0.39 10.4 0.1 2.4 2 1 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Nup54 PF13874.1 GAM18577.1 - 0.76 9.4 7.8 4.7 6.8 2.0 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.4 GAM18577.1 - 0.77 9.7 11.7 0.13 12.1 4.5 1.9 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.10 GAM18577.1 - 0.89 9.0 15.0 0.09 12.2 5.3 2.7 2 1 1 3 3 3 0 Septum formation initiator DUF972 PF06156.8 GAM18577.1 - 1.2 9.4 10.6 1.2 9.5 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 GAM18577.1 - 1.2 9.1 19.0 75 3.3 13.2 2.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1779 PF08680.5 GAM18577.1 - 1.5 8.6 8.0 0.77 9.5 4.2 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1779) IncA PF04156.9 GAM18577.1 - 1.7 8.1 16.6 6.8 6.2 11.5 1.9 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 GAM18577.1 - 2 7.4 17.3 0.33 9.9 7.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 GAM18577.1 - 3 5.5 5.9 3.4 5.4 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 GAM18577.1 - 4.5 7.7 11.0 0.82 10.1 2.2 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) YlqD PF11068.3 GAM18577.1 - 5.9 6.9 9.7 28 4.7 6.7 2.1 1 1 0 1 1 1 0 YlqD protein Rho_Binding PF08912.6 GAM18577.1 - 9.2 6.6 13.3 1.3 9.3 2.7 3.0 1 1 2 3 3 3 0 Rho Binding SNAP PF14938.1 GAM18578.1 - 4.9e-16 58.7 12.5 7.9e-16 58.0 8.7 1.3 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 GAM18578.1 - 0.009 15.9 3.8 0.41 10.6 1.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM18578.1 - 3.3 7.9 10.7 45 4.2 0.4 3.3 1 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Beta-lactamase PF00144.19 GAM18579.1 - 2.1e-43 148.5 0.0 2.7e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAM18579.1 - 0.13 11.5 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Abhydrolase_1 PF00561.15 GAM18580.1 - 6.9e-13 48.6 0.2 1.2e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM18580.1 - 1.2e-12 48.2 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM18580.1 - 6.5e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 GAM18580.1 - 7.6e-05 21.8 0.2 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) PGAP1 PF07819.8 GAM18580.1 - 0.0039 16.8 0.1 0.0094 15.5 0.1 1.6 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S28 PF05577.7 GAM18580.1 - 0.072 11.6 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 GAM18580.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Dicty_CTDC PF00526.13 GAM18581.1 - 4.4e-23 80.6 121.8 1.6e-06 27.8 4.2 10.8 10 0 0 10 10 10 10 Dictyostelium (slime mold) repeat DUF1183 PF06682.7 GAM18582.1 - 2.8e-70 237.4 11.0 2.8e-70 237.4 7.6 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) DUF912 PF06024.7 GAM18582.1 - 0.0035 17.3 0.4 0.072 13.1 0.2 2.2 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_US9 PF06072.6 GAM18582.1 - 0.035 13.9 0.4 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 LRR_4 PF12799.2 GAM18583.1 - 1.2 8.8 6.5 5.6 6.6 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PP2C PF00481.16 GAM18584.1 - 1.7e-36 125.8 1.5 1.9e-36 125.7 0.1 1.8 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM18584.1 - 5.3e-14 52.1 0.0 3.2e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SelP_N PF04592.9 GAM18584.1 - 0.24 10.7 17.4 0.47 9.8 12.1 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 GAM18584.1 - 0.7 8.8 12.8 1 8.3 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.11 GAM18584.1 - 6.7 5.9 10.5 11 5.2 7.3 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Vps23_core PF09454.5 GAM18585.1 - 9.7e-26 89.1 0.2 9.7e-26 89.1 0.1 2.7 3 0 0 3 3 3 1 Vps23 core domain UEV PF05743.8 GAM18585.1 - 6.7e-25 87.1 0.6 6.7e-25 87.1 0.4 1.9 2 0 0 2 2 2 1 UEV domain UQ_con PF00179.21 GAM18585.1 - 5.3e-06 25.9 2.8 5.3e-06 25.9 1.9 2.9 3 1 1 4 4 4 1 Ubiquitin-conjugating enzyme CAF-1_p150 PF11600.3 GAM18585.1 - 0.0092 15.3 15.5 0.0092 15.3 10.7 3.4 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 GAM18585.1 - 0.052 11.8 66.2 0.014 13.6 22.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 GLTSCR1 PF15249.1 GAM18586.1 - 7e-05 22.8 3.1 7e-05 22.8 2.2 3.9 4 1 1 5 5 5 1 Glioma tumor suppressor candidate region DENN PF02141.16 GAM18587.1 - 1.3e-26 93.4 4.9 1.6e-25 89.8 1.4 2.5 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 GAM18587.1 - 0.00017 21.4 3.8 0.00097 19.0 2.6 2.2 1 1 0 1 1 1 1 uDENN domain SPA PF08616.5 GAM18587.1 - 0.00037 20.1 0.3 0.001 18.7 0.2 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis dDENN PF03455.14 GAM18587.1 - 0.067 13.2 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 dDENN domain L_HGMIC_fpl PF10242.4 GAM18587.1 - 0.39 10.7 2.0 0.66 9.9 1.4 1.2 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein Pro_isomerase PF00160.16 GAM18588.1 - 4.7e-16 59.3 0.0 5.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 GAM18589.1 - 2.2e-76 256.4 0.0 3.7e-76 255.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18589.1 - 6e-45 153.3 0.0 9.5e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 GAM18589.1 - 3.1e-07 30.5 0.0 2.6e-06 27.6 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 GAM18589.1 - 4.2e-06 26.3 0.0 0.24 11.5 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.18 GAM18589.1 - 0.00031 20.4 1.0 5 7.1 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAM18589.1 - 0.0009 19.6 1.3 0.82 10.2 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Kinase-like PF14531.1 GAM18589.1 - 0.01 14.7 0.0 0.022 13.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 GAM18589.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NTP_transferase PF00483.18 GAM18590.1 - 1e-47 162.5 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 GAM18590.1 - 7.6e-12 44.1 3.0 1.7e-06 27.2 0.1 4.2 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAM18590.1 - 2.6e-09 37.3 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF257 PF03192.8 GAM18590.1 - 0.081 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Hexapep_2 PF14602.1 GAM18590.1 - 0.33 10.5 6.5 2.1 8.0 0.0 4.3 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase RNA12 PF10443.4 GAM18591.1 - 5.9e-83 278.7 0.0 2.4e-81 273.4 0.0 2.5 1 1 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 GAM18591.1 - 2.8e-05 23.6 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 GAM18591.1 - 0.00041 20.1 0.0 0.0014 18.4 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_35 PF14516.1 GAM18591.1 - 0.0057 15.3 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 GAM18591.1 - 0.01 15.9 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM18591.1 - 0.039 13.3 0.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_6 PF14259.1 GAM18591.1 - 0.04 13.9 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.1 GAM18591.1 - 0.069 13.4 2.0 3.9 7.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAM18591.1 - 0.081 12.8 0.0 0.49 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain DJ-1_PfpI PF01965.19 GAM18592.1 - 3.7e-28 97.8 0.0 4.5e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 GAM18592.1 - 1.7e-15 56.7 0.1 2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase Nop PF01798.13 GAM18593.1 - 1.9e-58 196.0 0.0 5e-58 194.6 0.0 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 GAM18593.1 - 3e-26 90.9 1.4 5.4e-26 90.1 1.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Borrelia_P83 PF05262.6 GAM18593.1 - 0.063 11.5 40.2 2.6 6.2 27.9 2.2 1 1 0 1 1 1 0 Borrelia P83/100 protein NOP5NT PF08156.8 GAM18594.1 - 1.7e-19 69.7 0.1 2.9e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain G-alpha PF00503.15 GAM18595.1 - 4.9e-115 384.3 4.1 6.5e-115 383.9 2.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM18595.1 - 5.5e-15 55.0 0.8 1.6e-11 43.7 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM18595.1 - 1.5e-06 27.5 0.9 0.00079 18.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM18595.1 - 0.006 17.0 0.5 0.78 10.2 0.0 2.9 1 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 GAM18595.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM18595.1 - 0.054 13.4 0.1 1.9 8.4 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM18595.1 - 0.062 12.7 0.0 0.85 9.0 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain LolA PF03548.10 GAM18595.1 - 0.091 12.3 0.2 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA CBS PF00571.23 GAM18597.1 - 1.1e-20 73.1 0.1 1e-07 31.6 0.0 4.3 4 0 0 4 4 4 3 CBS domain Pkinase PF00069.20 GAM18598.1 - 1.4e-71 240.7 0.0 1.8e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18598.1 - 2.7e-40 138.0 0.0 3.6e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM18598.1 - 3.5e-06 26.9 0.1 0.054 13.2 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM18598.1 - 4.5e-06 25.8 0.0 6.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM18598.1 - 9e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAM18598.1 - 0.0013 18.3 3.5 0.0031 17.1 0.6 2.1 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAM18598.1 - 0.021 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sulfotransfer_2 PF03567.9 GAM18599.1 - 7.4e-13 48.7 0.1 1.5e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM18599.1 - 9.9e-05 21.1 0.2 0.00025 19.8 0.1 1.7 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase 7tm_3 PF00003.17 GAM18600.1 - 7.1e-38 130.2 18.5 1.3e-37 129.3 12.8 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 GAM18600.1 - 1.4e-17 63.4 0.1 2e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Basic membrane protein Transglut_core PF01841.14 GAM18601.1 - 3.6e-11 43.2 0.0 6.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_C71 PF12386.3 GAM18601.1 - 0.03 13.7 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei PCI PF01399.22 GAM18602.1 - 1.6e-07 31.6 0.5 2.7e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 PCI domain DUF2659 PF10858.3 GAM18602.1 - 0.00098 18.5 1.2 0.002 17.5 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2659) WD40 PF00400.27 GAM18603.1 - 9.5e-44 145.7 12.7 1.6e-09 37.2 0.0 7.3 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM18603.1 - 0.0013 18.2 0.0 0.03 13.7 0.0 2.4 1 1 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.1 GAM18603.1 - 0.0091 15.7 2.3 15 5.4 0.0 4.3 2 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Sec7_N PF12783.2 GAM18604.1 - 1.9e-26 92.4 8.2 5e-26 91.1 0.5 3.3 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAM18604.1 - 1.5e-07 30.8 0.4 1.5e-07 30.8 0.3 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF3841 PF12952.2 GAM18604.1 - 0.048 13.1 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3841) Calreticulin PF00262.13 GAM18605.1 - 7.6e-140 465.7 7.4 1.2e-139 465.1 5.1 1.2 1 0 0 1 1 1 1 Calreticulin family FAM176 PF14851.1 GAM18605.1 - 0.025 14.2 0.2 0.025 14.2 0.1 2.5 2 1 1 3 3 3 0 FAM176 family DUF883 PF05957.8 GAM18605.1 - 0.029 14.7 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Pap_E4 PF02711.9 GAM18605.1 - 0.091 13.5 1.6 0.28 12.0 1.1 1.8 1 0 0 1 1 1 0 E4 protein LMBR1 PF04791.11 GAM18606.1 - 9.4e-43 146.4 33.7 4.6e-42 144.2 23.4 1.8 1 1 0 1 1 1 1 LMBR1-like membrane protein Thioredoxin PF00085.15 GAM18607.1 - 5.7e-26 90.2 0.0 6.9e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 GAM18607.1 - 1.2e-08 35.0 0.0 2.5e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAM18607.1 - 2.6e-07 30.5 0.0 4e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 GAM18607.1 - 3.8e-07 30.1 0.0 3.1e-05 24.0 0.0 2.5 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.1 GAM18607.1 - 1.3e-05 24.7 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 GAM18607.1 - 0.0025 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF4203 PF13886.1 GAM18608.1 - 3.9e-07 29.7 26.4 4.7e-07 29.4 18.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) PsbM PF05151.7 GAM18608.1 - 0.01 15.4 1.3 0.029 13.9 0.9 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) AAA PF00004.24 GAM18609.1 - 1.2e-98 326.3 0.0 1.7e-48 164.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAM18609.1 - 5.8e-21 74.2 0.3 2.2e-20 72.4 0.2 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 GAM18609.1 - 1.9e-14 53.2 0.0 4.2e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM18609.1 - 2.6e-13 50.2 0.2 5.3e-05 23.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAM18609.1 - 2.7e-13 50.2 0.0 4.3e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM18609.1 - 1.3e-12 48.1 0.0 4.8e-05 23.4 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 GAM18609.1 - 1.3e-12 47.7 0.0 5.5e-06 26.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 GAM18609.1 - 1.3e-11 45.3 0.0 0.00011 22.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM18609.1 - 1.5e-11 44.1 0.4 1.1e-05 25.1 0.0 3.8 4 2 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAM18609.1 - 2.7e-11 43.4 0.0 1.9e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAM18609.1 - 5.1e-09 35.5 0.0 0.0012 18.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin CDC48_2 PF02933.12 GAM18609.1 - 5.9e-09 35.4 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 GAM18609.1 - 2.8e-08 32.8 0.0 0.0013 17.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus Arch_ATPase PF01637.13 GAM18609.1 - 5.7e-08 32.7 0.1 0.21 11.2 0.0 3.6 2 2 1 3 3 3 2 Archaeal ATPase RNA_helicase PF00910.17 GAM18609.1 - 7.4e-08 32.5 0.0 0.0074 16.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 GAM18609.1 - 9.3e-08 31.4 0.4 0.0089 15.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM18609.1 - 9.7e-08 31.6 0.0 0.0085 15.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 GAM18609.1 - 1e-07 31.5 2.9 0.38 10.1 0.0 4.1 2 2 0 4 4 4 3 AAA domain AAA_18 PF13238.1 GAM18609.1 - 3.1e-07 30.7 0.0 0.027 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM18609.1 - 3.3e-07 30.4 0.0 0.035 14.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain Vps4_C PF09336.5 GAM18609.1 - 7.3e-07 28.9 0.1 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 GAM18609.1 - 8.2e-07 29.1 0.0 0.031 14.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 GAM18609.1 - 8.2e-07 28.8 0.1 0.14 11.7 0.0 3.9 3 1 0 4 4 4 2 NACHT domain Viral_helicase1 PF01443.13 GAM18609.1 - 8.7e-07 28.6 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 GAM18609.1 - 2.2e-06 28.0 0.0 0.019 15.2 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 GAM18609.1 - 3.5e-06 26.8 0.0 0.028 14.0 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein Parvo_NS1 PF01057.12 GAM18609.1 - 4e-06 25.9 0.1 0.024 13.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 GAM18609.1 - 7.2e-06 25.6 1.0 0.09 12.5 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain ResIII PF04851.10 GAM18609.1 - 1.5e-05 24.9 0.0 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 GAM18609.1 - 1.5e-05 24.0 0.1 0.1 11.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain KaiC PF06745.8 GAM18609.1 - 1.6e-05 24.1 0.5 2 7.4 0.0 3.4 2 1 1 3 3 3 2 KaiC Sigma54_activat PF00158.21 GAM18609.1 - 6.2e-05 22.5 0.0 0.74 9.2 0.0 3.4 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 GAM18609.1 - 6.8e-05 22.5 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 GAM18609.1 - 0.00016 20.6 0.0 0.13 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.1 GAM18609.1 - 0.0002 21.3 0.0 0.068 13.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.6 GAM18609.1 - 0.00042 19.9 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 GAM18609.1 - 0.00052 19.7 0.2 0.82 9.3 0.0 3.6 3 0 0 3 3 3 1 NTPase Rad17 PF03215.10 GAM18609.1 - 0.00079 18.2 0.0 1 7.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein SKI PF01202.17 GAM18609.1 - 0.001 18.9 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase PhoH PF02562.11 GAM18609.1 - 0.0017 17.5 0.1 0.86 8.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ATP-synt_ab PF00006.20 GAM18609.1 - 0.0018 17.8 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 GAM18609.1 - 0.0019 18.5 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM18609.1 - 0.0049 16.3 0.2 2.4 7.5 0.0 3.6 3 1 1 4 4 4 1 AAA-like domain UPF0079 PF02367.12 GAM18609.1 - 0.0058 16.2 0.0 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 GAM18609.1 - 0.016 14.2 0.0 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 GAM18609.1 - 0.016 14.7 0.0 3.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 GAM18609.1 - 0.022 13.7 0.0 2.2 7.1 0.0 3.0 2 1 1 3 3 3 0 KAP family P-loop domain AAA_11 PF13086.1 GAM18609.1 - 0.047 13.2 0.0 8.1 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 GAM18609.1 - 0.08 11.7 0.0 7.3 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_30 PF13604.1 GAM18609.1 - 0.088 12.3 0.0 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 GAM18609.1 - 0.11 11.7 0.1 10 5.2 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DAP3 PF10236.4 GAM18609.1 - 0.16 10.9 0.0 14 4.5 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Hid1 PF12722.2 GAM18610.1 - 1.9e-115 386.6 40.0 3.1e-104 349.5 19.4 2.6 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 GAM18610.1 - 5.2e-81 272.7 20.0 1e-79 268.4 13.9 2.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TFCD_C PF12612.3 GAM18610.1 - 0.027 13.8 1.8 2.9 7.2 0.1 3.4 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal Mem_trans PF03547.13 GAM18610.1 - 8.3 4.5 14.2 0.23 9.7 2.8 2.7 2 1 1 3 3 3 0 Membrane transport protein CBS PF00571.23 GAM18612.1 - 1.1e-25 89.1 4.6 1.1e-08 34.6 0.0 4.3 4 0 0 4 4 4 3 CBS domain Proteasom_PSMB PF10508.4 GAM18614.1 - 1.3e-28 99.5 0.6 2e-28 98.9 0.4 1.3 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT PF02985.17 GAM18614.1 - 0.046 13.8 0.0 11 6.3 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat IPP-2 PF04979.9 GAM18615.1 - 2.8e-10 40.5 26.5 1.4e-06 28.5 7.2 4.7 2 2 2 4 4 4 2 Protein phosphatase inhibitor 2 (IPP-2) zf-DHHC PF01529.15 GAM18616.1 - 1.3e-35 122.3 8.8 1.3e-35 122.3 6.1 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Oxidored_q2 PF00420.19 GAM18616.1 - 0.11 12.1 4.0 0.14 11.7 0.6 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RDD PF06271.7 GAM18616.1 - 1.1 9.1 7.4 4.3 7.2 0.2 2.3 2 0 0 2 2 2 0 RDD family Transket_pyr PF02779.19 GAM18617.1 - 4.2e-57 192.5 0.0 6.3e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAM18617.1 - 1.6e-43 148.5 0.0 2.6e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component RabGAP-TBC PF00566.13 GAM18618.1 - 1.1e-57 194.9 1.2 1.6e-57 194.4 0.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NusG PF02357.14 GAM18618.1 - 0.017 15.3 0.1 0.15 12.2 0.0 2.3 1 1 0 1 1 1 0 Transcription termination factor nusG Collar PF07484.7 GAM18618.1 - 0.078 12.7 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Collar Domain YL1_C PF08265.6 GAM18619.1 - 2.1e-13 49.5 2.1 4e-13 48.6 1.0 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain BUD22 PF09073.5 GAM18620.1 - 0.72 8.8 28.7 0.95 8.4 19.9 1.1 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 GAM18620.1 - 1.5 6.4 6.2 1.8 6.1 4.3 1.1 1 0 0 1 1 1 0 Ycf1 VHS PF00790.14 GAM18621.1 - 3e-23 82.0 0.2 6.3e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 GAM18621.1 - 5e-10 39.2 2.3 2e-09 37.3 1.6 2.0 1 0 0 1 1 1 1 GAT domain Rhomboid PF01694.17 GAM18622.1 - 2.6e-18 66.4 16.4 5.1e-18 65.4 11.3 1.5 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 GAM18622.1 - 1.2e-06 28.2 17.4 1.6e-06 27.7 12.1 1.2 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 GAM18622.1 - 0.0064 16.7 2.9 0.0064 16.7 2.0 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Ribosomal_S17e PF00833.13 GAM18623.1 - 4.4e-56 187.8 0.6 5.1e-56 187.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 MFS_1 PF07690.11 GAM18624.1 - 6.6e-19 67.8 43.8 6.6e-19 67.8 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM18624.1 - 3.7e-10 38.7 38.9 3.7e-10 38.7 26.9 2.0 2 1 0 2 2 2 1 MFS/sugar transport protein C_GCAxxG_C_C PF09719.5 GAM18624.1 - 0.3 10.8 0.8 0.71 9.6 0.6 1.7 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Pkinase PF00069.20 GAM18625.1 - 8.7e-74 247.9 0.7 1.1e-73 247.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18625.1 - 9.5e-36 123.1 0.0 1.6e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAM18625.1 - 5.5e-07 30.0 0.2 5.5e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM18625.1 - 2.4e-05 23.4 0.0 0.0002 20.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM18625.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM18625.1 - 0.031 13.3 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.8 GAM18625.1 - 1.1 9.0 25.7 1.5 8.5 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 GAM18625.1 - 2 8.0 10.6 3 7.4 7.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.27 GAM18626.1 - 5.7e-68 222.5 30.1 6.2e-12 44.9 0.1 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat LisH PF08513.6 GAM18626.1 - 1.2e-09 37.6 0.3 2.7e-09 36.4 0.2 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 GAM18626.1 - 1.3e-09 38.0 4.9 3.3e-05 23.6 0.1 4.0 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 GAM18626.1 - 0.004 16.2 0.0 0.012 14.6 0.0 1.8 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.1 GAM18626.1 - 0.013 14.6 0.4 1.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Sec62 PF03839.11 GAM18626.1 - 4.8 6.5 9.9 7.9 5.8 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase PF00069.20 GAM18627.1 - 2.1e-77 259.7 0.0 2.7e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18627.1 - 7.4e-38 130.0 0.0 1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCHH PF10283.4 GAM18627.1 - 9.8e-13 47.6 4.7 2.3e-12 46.5 3.3 1.7 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif FHA PF00498.21 GAM18627.1 - 2.2e-11 43.7 0.1 5e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAM18627.1 - 5.3e-09 35.4 0.0 2e-07 30.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAM18627.1 - 1.7e-07 30.5 0.1 2.7e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM18627.1 - 0.00049 19.4 0.2 0.0011 18.3 0.1 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 GAM18627.1 - 0.024 14.3 0.0 2.3 7.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family BRE1 PF08647.6 GAM18627.1 - 0.04 13.8 0.7 0.082 12.8 0.5 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Ank_2 PF12796.2 GAM18628.1 - 9e-06 25.9 0.3 0.014 15.6 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM18628.1 - 9.1e-05 22.5 0.2 0.83 9.9 0.0 4.8 3 2 3 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18628.1 - 0.0049 16.9 0.4 7.2 7.1 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAM18628.1 - 0.0068 16.8 0.4 10 6.8 0.0 3.8 2 2 3 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM18628.1 - 0.033 14.0 4.2 5.7 6.9 0.0 4.8 7 0 0 7 7 7 0 Ankyrin repeat CBS PF00571.23 GAM18631.1 - 3.2e-36 122.8 1.5 1.2e-11 44.1 0.0 4.4 4 0 0 4 4 4 4 CBS domain WD40 PF00400.27 GAM18632.1 - 5e-59 194.2 30.4 6.7e-08 32.1 0.7 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat DENN PF02141.16 GAM18632.1 - 6.3e-50 169.4 8.2 6.3e-50 169.4 5.7 2.2 3 0 0 3 3 3 1 DENN (AEX-3) domain uDENN PF03456.13 GAM18632.1 - 1.7e-18 66.3 0.5 4.9e-18 64.8 0.3 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 GAM18632.1 - 6.1e-15 55.0 1.4 1.3e-14 53.9 1.0 1.6 1 0 0 1 1 1 1 dDENN domain C2 PF00168.25 GAM18632.1 - 1.4e-11 44.1 2.8 2.6e-11 43.2 0.9 2.3 2 0 0 2 2 2 1 C2 domain SBF2 PF12335.3 GAM18632.1 - 1.9e-07 30.6 0.7 1.9e-07 30.6 0.5 2.5 2 0 0 2 2 2 1 Myotubularin protein CAF-1_p150 PF11600.3 GAM18632.1 - 9.6e-05 21.8 20.2 9.6e-05 21.8 14.0 3.2 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal JAB PF01398.16 GAM18633.1 - 5.7e-36 122.7 0.3 1.4e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 GAM18633.1 - 1.5e-27 95.9 3.9 1.5e-27 95.9 2.7 2.0 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 GAM18633.1 - 2.7e-09 36.5 0.0 4.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain G6PD_bact PF10786.4 GAM18633.1 - 0.021 14.2 0.9 0.031 13.7 0.6 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Methyltransf_16 PF10294.4 GAM18634.1 - 1.8e-19 69.8 0.2 3.4e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAM18634.1 - 0.00031 21.2 0.0 0.00089 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM18634.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RcsC PF09456.5 GAM18634.1 - 0.046 13.3 0.2 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 RcsC Alpha-Beta-Loop (ABL) Methyltransf_11 PF08241.7 GAM18634.1 - 0.047 14.1 0.3 0.21 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.14 GAM18634.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PH PF00169.24 GAM18635.1 - 4.5e-24 84.6 0.0 4.7e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 PH domain TPR_11 PF13414.1 GAM18635.1 - 1.6e-17 62.9 5.8 1.2e-08 34.5 0.2 3.0 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 GAM18635.1 - 3.4e-13 49.7 0.7 1.6e-05 25.1 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM18635.1 - 1.5e-10 40.1 2.5 0.21 11.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat PH_3 PF14593.1 GAM18635.1 - 1.4e-06 28.0 0.9 2.2e-05 24.2 0.2 2.9 2 1 0 2 2 2 1 PH domain TPR_1 PF00515.23 GAM18635.1 - 1.1e-05 24.8 7.6 0.49 10.0 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM18635.1 - 1.5e-05 25.5 0.0 0.0083 16.7 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18635.1 - 2.6e-05 23.6 1.9 0.43 10.4 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat PH_6 PF15406.1 GAM18635.1 - 0.00014 21.8 0.0 0.0062 16.5 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain C2 PF00168.25 GAM18635.1 - 0.0002 21.1 0.0 0.00071 19.3 0.0 2.0 1 1 0 1 1 1 1 C2 domain TPR_14 PF13428.1 GAM18635.1 - 0.00056 20.3 0.0 24 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM18635.1 - 0.012 15.7 1.7 2.8 8.3 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Ribosomal_S7 PF00177.16 GAM18636.1 - 8.1e-37 126.0 0.3 9.7e-37 125.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ank_2 PF12796.2 GAM18637.1 - 3.8e-09 36.7 0.0 0.26 11.6 0.0 4.8 4 3 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM18637.1 - 0.00062 19.4 0.1 17 5.4 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 GAM18637.1 - 0.001 19.0 0.2 15 6.2 0.0 6.0 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 GAM18637.1 - 0.0078 16.7 0.1 1.8e+02 2.7 0.0 5.7 6 0 0 6 6 6 0 Ankyrin repeats (many copies) DUF1162 PF06650.7 GAM18638.1 - 2.1e-45 155.1 8.9 2.5e-43 148.2 0.1 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM18638.1 - 4e-38 129.5 0.5 2.7e-37 126.9 0.3 2.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAM18638.1 - 1.9e-07 31.1 1.0 5.8e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 ATG C terminal domain F-box-like PF12937.2 GAM18640.1 - 6.5e-07 28.9 1.4 7e-07 28.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like PIP5K PF01504.13 GAM18641.1 - 9.2e-25 87.1 0.4 1.2e-23 83.5 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4407 PF14362.1 GAM18641.1 - 2 7.2 11.1 3.2 6.6 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SET PF00856.23 GAM18642.1 - 1e-10 42.1 0.1 5.7e-10 39.7 0.1 2.2 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 GAM18642.1 - 4.2e-06 26.3 9.7 0.0004 19.9 2.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.1 GAM18642.1 - 0.00029 20.7 1.2 0.00064 19.7 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM18642.1 - 0.00073 19.1 2.6 0.1 12.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM18642.1 - 0.0015 18.0 0.9 0.0015 18.0 0.6 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat MTHFR_C PF12225.3 GAM18642.1 - 0.0018 17.7 3.2 0.0018 17.7 2.2 2.6 2 0 0 2 2 2 1 Methylene-tetrahydrofolate reductase C terminal TPR_16 PF13432.1 GAM18642.1 - 0.0029 18.2 2.2 0.016 15.8 1.7 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM18642.1 - 0.003 17.3 8.0 0.0065 16.3 0.6 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18642.1 - 0.011 15.4 0.1 0.06 13.1 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4542 PF15075.1 GAM18642.1 - 0.028 14.3 0.5 0.067 13.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) TPR_12 PF13424.1 GAM18642.1 - 0.17 11.8 5.6 0.06 13.2 0.8 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM18642.1 - 0.29 11.6 3.8 0.39 11.2 1.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cys_rich_KTR PF14205.1 GAM18642.1 - 0.92 9.0 8.5 11 5.5 0.0 3.5 3 0 0 3 3 3 0 Cysteine-rich KTR zf-RING_6 PF14835.1 GAM18642.1 - 6.9 6.5 12.8 0.36 10.6 1.0 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FTCD_N PF07837.7 GAM18645.1 - 7e-75 250.4 0.0 1.2e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD PF02971.9 GAM18645.1 - 3.1e-57 192.2 0.0 6e-57 191.3 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase domain FTCD_C PF04961.7 GAM18645.1 - 2.5e-54 183.5 0.4 3.7e-54 182.9 0.3 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase TMEM154 PF15102.1 GAM18646.1 - 0.54 9.9 10.0 1.1 8.9 6.9 1.6 1 0 0 1 1 1 0 TMEM154 protein family Phage_integrase PF00589.17 GAM18648.1 - 3e-05 23.7 1.4 0.001 18.7 0.1 2.5 2 1 0 2 2 2 2 Phage integrase family Phage_int_SAM_1 PF02899.12 GAM18648.1 - 4.6e-05 23.4 1.3 8.5e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 GAM18648.1 - 0.00082 19.6 0.4 0.002 18.3 0.0 1.8 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Coatomer_WDAD PF04053.9 GAM18649.1 - 5.7e-11 41.8 5.6 0.074 11.8 0.0 5.3 5 1 1 6 6 6 4 Coatomer WD associated region WD40 PF00400.27 GAM18649.1 - 1.3e-05 24.8 0.4 0.013 15.3 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat TPR_11 PF13414.1 GAM18649.1 - 1.7 8.3 5.0 2.4 7.8 0.2 3.2 3 1 1 4 4 4 0 TPR repeat DUF4065 PF13274.1 GAM18650.1 - 0.09 13.4 0.4 0.24 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Herpes_UL21 PF03252.8 GAM18651.1 - 0.0071 14.8 0.0 0.01 14.3 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus UL21 Ycf54 PF10674.4 GAM18651.1 - 0.095 12.8 0.2 5.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) CAP_GLY PF01302.20 GAM18653.1 - 1.7e-21 75.6 0.2 3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 GAM18653.1 - 1.7e-19 69.8 1.2 2.8e-19 69.1 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain SpoU_methylase PF00588.14 GAM18654.1 - 5.2e-27 94.4 0.1 1.2e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF4047 PF13256.1 GAM18654.1 - 0.039 13.9 2.2 5.6 6.9 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) TIG PF01833.19 GAM18655.1 - 7.9e-14 51.4 61.2 3e-05 23.9 5.2 7.8 5 3 2 7 7 7 5 IPT/TIG domain EGF_2 PF07974.8 GAM18655.1 - 0.0034 17.5 10.1 0.0081 16.3 7.0 1.7 1 0 0 1 1 1 1 EGF-like domain MORN PF02493.15 GAM18655.1 - 6.6 6.6 5.4 0.74 9.6 0.1 2.3 3 0 0 3 3 3 0 MORN repeat Corona_M PF01635.13 GAM18656.1 - 0.045 12.6 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein EGF_2 PF07974.8 GAM18657.1 - 0.0015 18.6 14.0 0.0036 17.4 9.7 1.7 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 GAM18657.1 - 0.0061 16.6 4.0 0.014 15.4 2.8 1.6 1 0 0 1 1 1 1 EB module DUF3753 PF12575.3 GAM18657.1 - 0.97 9.2 3.4 16 5.3 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Metallophos PF00149.23 GAM18658.1 - 1.2e-12 47.6 3.3 4.1e-12 45.9 2.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM18658.1 - 6.4e-07 29.3 0.0 8.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ost4 PF10215.4 GAM18658.1 - 0.81 9.2 5.9 2.9 7.4 4.1 1.9 1 0 0 1 1 1 0 Oligosaccaryltransferase Pyr_redox PF00070.22 GAM18659.1 - 1e-20 73.8 0.6 7.9e-13 48.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM18659.1 - 3.3e-13 49.9 0.0 9e-13 48.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM18659.1 - 1.5e-08 34.9 0.2 0.00014 22.0 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM18659.1 - 1.7e-07 30.4 0.0 0.15 10.9 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM18659.1 - 4.2e-07 29.2 2.3 0.023 13.5 0.0 3.3 2 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM18659.1 - 1.8e-06 27.8 0.0 0.01 15.8 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DUF1188 PF06690.6 GAM18659.1 - 1.8e-06 27.2 0.2 0.0023 17.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) Lycopene_cycl PF05834.7 GAM18659.1 - 1.6e-05 24.0 0.0 0.019 13.9 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 GAM18659.1 - 2.9e-05 24.2 0.3 0.17 12.1 0.0 2.7 3 0 0 3 3 2 2 Putative NAD(P)-binding TrkA_N PF02254.13 GAM18659.1 - 3.6e-05 23.7 0.2 0.4 10.7 0.0 2.8 2 0 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.9 GAM18659.1 - 9.2e-05 21.2 0.3 0.032 12.8 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM18659.1 - 0.00019 21.2 4.8 0.43 10.3 0.0 4.2 2 2 1 4 4 4 1 FAD-NAD(P)-binding FMO-like PF00743.14 GAM18659.1 - 0.00019 19.7 1.5 0.73 7.9 0.0 3.4 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like HI0933_like PF03486.9 GAM18659.1 - 0.00039 19.0 0.0 0.054 11.9 0.0 2.6 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 GAM18659.1 - 0.0007 19.2 0.0 0.84 9.2 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM18659.1 - 0.001 18.1 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 GAM18659.1 - 0.0019 17.6 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAM18659.1 - 0.0042 16.8 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glycoprotein_B PF00606.13 GAM18659.1 - 0.0066 14.5 0.2 0.0066 14.5 0.2 1.4 2 0 0 2 2 2 1 Herpesvirus Glycoprotein B Shikimate_DH PF01488.15 GAM18659.1 - 0.014 15.4 0.1 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAM18659.1 - 0.015 14.2 1.4 2 7.3 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 GAM18659.1 - 0.038 14.2 0.3 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FYVE PF01363.16 GAM18660.1 - 4.3e-19 68.1 3.2 5e-19 67.9 2.2 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 GAM18660.1 - 0.00099 18.9 4.0 0.0013 18.5 2.8 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.16 GAM18660.1 - 0.032 14.1 5.6 0.066 13.0 3.8 1.5 1 0 0 1 1 1 0 IBR domain DUF4637 PF15470.1 GAM18660.1 - 0.062 12.9 1.6 0.083 12.5 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) HypA PF01155.14 GAM18660.1 - 0.14 11.8 3.7 0.31 10.7 2.5 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Fer4_17 PF13534.1 GAM18660.1 - 0.23 11.8 4.8 4.9 7.5 1.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-C3HC4_4 PF15227.1 GAM18660.1 - 1 9.3 6.0 0.59 10.0 1.9 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FNIP PF05725.7 GAM18661.1 - 1.4e-77 255.3 16.4 5.8e-14 51.7 1.4 8.5 7 1 0 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM18661.1 - 0.0006 19.7 7.1 6.3 6.8 0.0 6.4 3 2 3 6 6 6 2 Protein of unknown function (DUF1769) Prenyltrans PF00432.16 GAM18662.1 - 5.4e-60 198.5 6.8 2.4e-13 49.3 0.1 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM18662.1 - 4.4e-37 126.9 0.0 1.2e-17 64.3 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM18662.1 - 5.7e-11 42.3 0.0 2.8e-07 30.4 0.0 3.2 2 1 1 3 3 3 2 Prenyltransferase-like DEAD PF00270.24 GAM18663.1 - 1.3e-30 106.0 0.0 2.3e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM18663.1 - 2.4e-21 75.3 1.3 3.5e-21 74.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Nop14 PF04147.7 GAM18663.1 - 0.0075 14.2 36.3 0.012 13.5 25.1 1.2 1 0 0 1 1 1 1 Nop14-like family CMS1 PF14617.1 GAM18663.1 - 0.05 12.6 0.0 0.05 12.6 0.0 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 GAM18663.1 - 0.086 12.9 0.4 0.73 9.9 0.2 2.7 1 1 0 1 1 1 0 AAA domain MIP-T3 PF10243.4 GAM18663.1 - 3.6 5.9 38.6 5.5 5.3 26.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SSP160 PF06933.6 GAM18663.1 - 3.9 5.3 8.7 5.7 4.7 6.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SDA1 PF05285.7 GAM18663.1 - 5 6.3 34.8 9.2 5.4 24.1 1.4 1 0 0 1 1 1 0 SDA1 Formyl_trans_N PF00551.14 GAM18665.1 - 1.5e-24 86.5 0.0 2.6e-24 85.7 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 GAM18665.1 - 4e-07 30.0 0.0 1.4e-06 28.2 0.0 1.9 2 1 0 2 2 2 1 Formyl transferase, C-terminal domain THF_DHG_CYH_C PF02882.14 GAM18666.1 - 3.2e-56 188.8 0.6 1.1e-55 187.0 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAM18666.1 - 6.2e-35 119.7 1.0 6.2e-35 119.7 0.7 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SOBP PF15279.1 GAM18666.1 - 0.051 13.9 28.8 0.087 13.2 20.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.4 GAM18666.1 - 0.078 12.4 13.5 0.13 11.6 9.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 GAM18666.1 - 0.32 9.1 39.8 0.47 8.6 27.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 GAM18666.1 - 0.63 9.3 27.6 0.9 8.8 19.1 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 GAM18666.1 - 1.1 9.1 30.7 1.7 8.4 21.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 GAM18666.1 - 1.7 8.4 9.7 2.8 7.7 6.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AdoHcyase_NAD PF00670.16 GAM18666.1 - 1.8 8.3 4.8 0.52 10.1 0.3 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1900 PF08954.6 GAM18667.1 - 1.7e-38 131.1 0.0 2.7e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 GAM18667.1 - 1.2e-10 40.8 0.0 0.001 18.8 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF1899 PF08953.6 GAM18667.1 - 1.3e-05 24.7 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Peptidase_S9_N PF02897.10 GAM18667.1 - 0.13 10.8 0.0 0.48 8.9 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain RhoGEF PF00621.15 GAM18668.1 - 2.7e-47 160.9 2.3 2.7e-47 160.9 1.6 2.7 1 1 1 2 2 2 1 RhoGEF domain CH PF00307.26 GAM18668.1 - 1.6e-35 121.3 6.7 3.9e-13 49.3 0.0 4.1 4 0 0 4 4 4 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM18668.1 - 1.2e-10 40.9 1.0 0.00062 19.3 0.0 4.9 3 2 1 4 4 4 2 CAMSAP CH domain PH PF00169.24 GAM18668.1 - 3.9e-09 36.6 0.1 1.3e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 PH domain CDC24 PF06395.6 GAM18668.1 - 8.6e-06 25.7 3.9 0.029 14.4 0.0 3.7 3 0 0 3 3 3 2 CDC24 Calponin Herpes_UL14 PF03580.9 GAM18668.1 - 0.03 14.1 0.1 0.03 14.1 0.0 2.8 3 0 0 3 3 3 0 Herpesvirus UL14-like protein PIG-L PF02585.12 GAM18669.1 - 1e-09 38.9 0.0 6e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ricin_B_lectin PF00652.17 GAM18669.1 - 2.1e-09 37.4 0.4 6.3e-09 35.9 0.3 1.8 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain VCBS PF13517.1 GAM18669.1 - 0.0015 18.8 19.3 0.018 15.4 0.4 5.5 3 2 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 GAM18669.1 - 0.0022 17.4 0.1 0.053 12.9 0.0 2.5 1 1 1 2 2 2 1 Insecticide toxin TcdB middle/N-terminal region CDtoxinA PF03498.9 GAM18669.1 - 0.0033 16.8 0.6 1.2 8.5 0.0 2.4 1 1 1 2 2 2 2 Cytolethal distending toxin A/C family FG-GAP PF01839.18 GAM18669.1 - 0.0036 16.9 6.2 0.02 14.5 0.0 3.6 3 0 0 3 3 3 1 FG-GAP repeat RicinB_lectin_2 PF14200.1 GAM18669.1 - 0.035 14.4 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like COBRA1 PF06209.8 GAM18670.1 - 5.1e-66 223.2 13.0 5.1e-66 223.2 9.0 1.4 1 1 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Methylase_S PF01420.14 GAM18670.1 - 0.47 10.4 3.0 20 5.1 0.0 3.2 4 0 0 4 4 4 0 Type I restriction modification DNA specificity domain RNase_T PF00929.19 GAM18671.1 - 1.2e-32 113.4 0.5 1.4e-32 113.1 0.3 1.0 1 0 0 1 1 1 1 Exonuclease LCM PF04072.9 GAM18672.1 - 5.7e-36 123.7 0.0 2e-35 121.9 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Ribosomal_L14e PF01929.12 GAM18673.1 - 1.6e-20 73.2 1.3 1.6e-20 73.2 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 GAM18673.1 - 0.0011 18.5 0.1 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 KOW motif Adeno_E3_15_3 PF03307.9 GAM18674.1 - 0.039 13.6 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region V-ATPase_G PF03179.10 GAM18675.1 - 6e-28 97.2 10.0 6.5e-28 97.1 6.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 GAM18675.1 - 0.0021 17.8 9.1 0.0021 17.8 6.3 1.4 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) CTP-dep_RFKase PF01982.11 GAM18675.1 - 0.014 15.0 0.2 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF120 FliD_N PF02465.13 GAM18675.1 - 0.017 15.5 2.8 0.022 15.1 2.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus SpoIISA_toxin PF14171.1 GAM18675.1 - 0.16 11.1 1.5 0.18 11.0 1.0 1.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system HrpE PF06188.7 GAM18675.1 - 0.34 10.6 6.3 0.4 10.4 4.2 1.2 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATC_hydrolase PF14196.1 GAM18675.1 - 0.91 9.9 4.9 2.8 8.3 2.6 1.9 1 1 1 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Mss4 PF04421.8 GAM18676.1 - 1.6e-15 56.7 1.9 1.6e-15 56.7 0.1 1.9 2 0 0 2 2 2 1 Mss4 protein Yippee-Mis18 PF03226.9 GAM18676.1 - 0.17 11.9 3.6 1.7 8.7 2.8 2.2 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Epimerase PF01370.16 GAM18677.1 - 5.2e-52 176.6 0.0 6.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAM18677.1 - 3.2e-27 94.2 0.3 5.7e-27 93.4 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 GAM18677.1 - 5.1e-16 58.2 0.2 8.1e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAM18677.1 - 1.5e-15 56.9 0.1 1.5e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAM18677.1 - 2.1e-11 43.2 0.0 3.9e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM18677.1 - 3.3e-11 43.3 0.0 5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAM18677.1 - 9e-09 34.6 0.3 1.8e-07 30.3 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 GAM18677.1 - 5.3e-08 32.7 0.0 1e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM18677.1 - 5.8e-07 29.6 0.0 1.1e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM18677.1 - 0.013 14.7 0.1 0.046 12.9 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 GAM18677.1 - 0.074 12.4 0.1 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DivIC PF04977.10 GAM18678.1 - 0.0021 17.5 11.9 0.058 12.8 3.0 2.8 2 0 0 2 2 2 2 Septum formation initiator Filament PF00038.16 GAM18678.1 - 0.0033 16.9 17.3 0.0068 15.9 12.0 1.5 1 0 0 1 1 1 1 Intermediate filament protein DUF3450 PF11932.3 GAM18678.1 - 0.009 15.3 12.7 0.009 15.3 8.8 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) BLOC1_2 PF10046.4 GAM18678.1 - 0.028 14.5 5.8 0.028 14.5 4.0 3.0 1 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NOA36 PF06524.7 GAM18678.1 - 0.063 12.5 9.8 0.13 11.5 6.8 1.4 1 0 0 1 1 1 0 NOA36 protein bZIP_1 PF00170.16 GAM18678.1 - 0.28 11.1 13.8 0.89 9.5 5.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor CCDC155 PF14662.1 GAM18678.1 - 0.52 9.8 22.8 0.027 14.0 8.0 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Nucleoplasmin PF03066.10 GAM18678.1 - 0.56 9.7 15.7 0.042 13.3 7.0 1.9 2 0 0 2 2 2 0 Nucleoplasmin DivIVA PF05103.8 GAM18678.1 - 2.3 8.2 28.2 0.05 13.6 12.2 2.6 3 0 0 3 3 3 0 DivIVA protein DUF2514 PF10721.4 GAM18678.1 - 2.5 7.7 20.0 5 6.8 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) RhoGAP PF00620.22 GAM18680.1 - 2.1e-39 134.5 0.5 4.6e-39 133.4 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain Vps5 PF09325.5 GAM18681.1 - 1.3e-54 184.9 13.1 1.9e-54 184.4 9.1 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 GAM18681.1 - 1e-25 89.6 0.1 3.1e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 PX domain BAR PF03114.13 GAM18681.1 - 0.00014 21.4 5.9 0.0003 20.3 4.1 1.5 1 0 0 1 1 1 1 BAR domain Snapin_Pallidin PF14712.1 GAM18681.1 - 0.56 10.5 4.2 4.9 7.5 0.6 2.9 2 1 0 2 2 2 0 Snapin/Pallidin DUF4355 PF14265.1 GAM18681.1 - 2.4 8.1 13.4 0.32 10.9 5.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) bZIP_2 PF07716.10 GAM18682.1 - 0.00036 20.2 6.1 0.00036 20.2 4.2 4.6 4 1 1 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM18682.1 - 0.00047 20.0 3.5 0.00047 20.0 2.4 3.8 3 0 0 3 3 3 1 bZIP transcription factor TSC22 PF01166.13 GAM18682.1 - 0.15 12.0 0.2 0.15 12.0 0.1 5.0 4 0 0 4 4 4 0 TSC-22/dip/bun family Peptidase_S64 PF08192.6 GAM18682.1 - 4 5.6 38.3 0.025 12.9 15.9 2.2 2 0 0 2 2 2 0 Peptidase family S64 Glyco_trans_1_2 PF13524.1 GAM18682.1 - 4.1 7.7 5.4 17 5.7 0.7 2.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 bZIP_2 PF07716.10 GAM18683.1 - 2.4e-07 30.4 4.7 2.4e-07 30.4 3.3 4.9 5 0 0 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM18683.1 - 1.4e-05 24.9 3.3 1.4e-05 24.9 2.3 3.0 3 0 0 3 3 3 1 bZIP transcription factor CH PF00307.26 GAM18684.1 - 4e-31 107.2 0.3 2e-18 66.4 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain DUF2746 PF10874.3 GAM18684.1 - 0.0064 16.6 4.0 0.082 13.1 0.8 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2746) TMEM247 PF15444.1 GAM18684.1 - 0.033 14.0 2.6 0.053 13.3 1.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 CAMSAP_CH PF11971.3 GAM18684.1 - 0.1 12.2 0.0 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 CAMSAP CH domain Fib_alpha PF08702.5 GAM18684.1 - 3.1 7.8 9.0 0.66 10.1 3.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Rad60-SLD PF11976.3 GAM18686.1 - 3.6e-08 32.9 0.0 1.7e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM18686.1 - 4e-07 29.3 0.0 2e-06 27.0 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin family SOBP PF15279.1 GAM18686.1 - 0.45 10.8 32.5 0.25 11.6 16.2 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein PAT1 PF09770.4 GAM18686.1 - 1 7.4 55.1 0.57 8.3 28.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 GAM18686.1 - 1.8 7.8 43.5 0.077 12.3 21.9 2.1 2 0 0 2 2 2 0 SprA-related family TFIIA PF03153.8 GAM18686.1 - 2 8.2 43.9 1.6 8.5 21.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Motile_Sperm PF00635.21 GAM18688.1 - 8e-20 70.5 1.3 1.1e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Transposase_24 PF03004.9 GAM18689.1 - 0.01 15.6 1.7 0.01 15.6 1.2 2.4 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) Cut8_N PF14482.1 GAM18689.1 - 0.036 14.0 1.7 0.036 14.0 1.2 3.1 4 0 0 4 4 4 0 Cut8 proteasome-binding domain TFIIE-A_C-term PF11521.3 GAM18689.1 - 0.36 10.8 4.2 0.47 10.4 0.2 2.8 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Pneumo_att_G PF05539.6 GAM18689.1 - 2.2 7.5 18.1 3.3 6.9 12.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G IER PF05760.7 GAM18689.1 - 8.5 6.2 22.0 0.5 10.2 11.4 1.6 2 0 0 2 2 2 0 Immediate early response protein (IER) Voltage_CLC PF00654.15 GAM18690.1 - 4.5e-103 344.9 19.8 4.5e-103 344.9 13.7 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 GAM18690.1 - 2.2e-19 68.9 0.6 3.1e-09 36.4 0.0 2.7 3 0 0 3 3 3 2 CBS domain P22_AR_C PF10548.4 GAM18690.1 - 0.025 14.4 0.0 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain DUF390 PF04094.9 GAM18691.1 - 0.21 9.5 0.0 0.33 8.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) FNIP PF05725.7 GAM18692.1 - 6.6e-40 134.8 24.8 7.9e-12 44.9 0.1 6.4 3 1 4 7 7 7 7 FNIP Repeat ABC_tran PF00005.22 GAM18693.1 - 1.8e-35 122.2 0.0 3.2e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAM18693.1 - 3.6e-28 98.7 15.3 4.7e-28 98.3 10.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM18693.1 - 5e-07 29.1 0.3 2.6e-05 23.5 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM18693.1 - 1.5e-06 28.3 0.5 0.00081 19.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM18693.1 - 0.00019 22.2 0.0 0.00053 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM18693.1 - 0.00049 19.5 0.2 0.002 17.6 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 GAM18693.1 - 0.001 19.0 0.1 0.31 10.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 GAM18693.1 - 0.0012 17.9 0.0 0.0032 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAM18693.1 - 0.0015 18.8 0.0 0.0089 16.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 GAM18693.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 GAM18693.1 - 0.0041 16.6 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 GAM18693.1 - 0.0049 17.0 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM18693.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 GAM18693.1 - 0.0078 15.3 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 GAM18693.1 - 0.0088 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 GAM18693.1 - 0.012 15.0 0.0 0.13 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 GAM18693.1 - 0.016 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAM18693.1 - 0.028 14.3 0.4 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 GAM18693.1 - 0.034 14.6 0.0 0.097 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 GAM18693.1 - 0.038 12.6 0.2 0.26 9.9 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 GAM18693.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM18693.1 - 0.085 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 GAM18693.1 - 0.21 11.5 1.9 0.75 9.7 0.1 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit L51_S25_CI-B8 PF05047.11 GAM18695.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TPR_14 PF13428.1 GAM18696.1 - 4.1e-14 51.7 8.0 0.013 16.0 0.0 9.3 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM18696.1 - 7.1e-12 45.4 4.6 0.24 11.7 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_15 PF13429.1 GAM18696.1 - 3.9e-09 35.9 16.2 9.4e-05 21.5 0.2 5.3 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM18696.1 - 1.4e-08 34.5 14.3 0.033 14.1 0.0 6.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM18696.1 - 1e-07 32.4 11.4 0.77 10.5 0.1 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat Suf PF05843.9 GAM18696.1 - 8.2e-07 29.0 40.2 0.022 14.5 0.1 5.8 5 2 1 6 6 5 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 GAM18696.1 - 6.1e-06 25.7 20.2 0.049 13.5 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM18696.1 - 0.00011 21.7 13.3 0.45 10.1 0.0 6.0 7 1 0 8 8 8 2 TPR repeat Mad3_BUB1_I PF08311.7 GAM18696.1 - 0.00046 19.9 26.1 0.53 10.0 0.1 7.9 5 2 3 8 8 8 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 GAM18696.1 - 0.0052 16.4 6.5 0.17 11.7 0.2 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM18696.1 - 0.019 14.7 0.1 0.019 14.7 0.1 5.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM18696.1 - 0.026 14.4 2.2 0.71 9.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HAT PF02184.11 GAM18696.1 - 0.16 11.7 8.7 0.98 9.2 0.1 6.0 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat PBP1_TM PF14812.1 GAM18696.1 - 0.77 10.1 9.0 2.7 8.3 6.2 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_6 PF13174.1 GAM18696.1 - 0.95 10.0 16.3 19 5.9 0.1 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat AMP-binding PF00501.23 GAM18697.1 - 9.2e-59 198.8 0.0 1.3e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM18697.1 - 3.3e-54 183.4 0.0 5.2e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM18697.1 - 3.5e-08 33.1 0.0 1.1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM18697.1 - 1.1e-05 24.3 0.1 3.4e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM18697.1 - 0.019 13.8 0.1 0.072 11.9 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain PP-binding PF00550.20 GAM18697.1 - 0.05 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site ZZ PF00569.12 GAM18697.1 - 0.057 12.9 2.9 0.12 11.9 2.0 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type TPR_11 PF13414.1 GAM18698.1 - 3e-13 49.1 7.4 9.8e-08 31.5 0.7 3.5 4 1 1 5 5 4 2 TPR repeat TPR_2 PF07719.12 GAM18698.1 - 5.8e-11 41.4 9.5 1.3e-05 24.6 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM18698.1 - 1e-07 32.4 4.8 0.0051 17.4 1.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat SET PF00856.23 GAM18698.1 - 1.5e-07 31.8 0.0 5.4e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 SET domain TPR_19 PF14559.1 GAM18698.1 - 6.1e-07 29.6 3.3 0.0045 17.2 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM18698.1 - 2e-06 27.1 10.6 2.1e-05 23.9 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18698.1 - 2.5e-06 26.8 2.4 0.038 13.7 0.5 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM18698.1 - 9.6e-06 25.8 2.3 0.019 15.5 0.2 3.4 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM18698.1 - 0.00021 21.4 1.6 0.0093 16.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM18698.1 - 0.00024 20.9 6.4 0.033 14.1 0.4 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM18698.1 - 0.024 14.7 5.3 0.03 14.4 0.7 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAM18698.1 - 0.05 13.4 0.9 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM18698.1 - 0.097 12.5 0.3 1.2 9.0 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 GAM18698.1 - 0.16 12.2 1.1 0.94 9.7 0.8 2.2 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_17 PF13431.1 GAM18698.1 - 1.2 9.5 7.3 2.5 8.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Beta_helix PF13229.1 GAM18699.1 - 2.1e-13 50.3 40.4 7.8e-08 32.2 7.7 3.7 1 1 2 3 3 3 3 Right handed beta helix region Cornifin PF02389.10 GAM18699.1 - 5.3e-05 23.0 7.8 0.0001 22.1 5.4 1.4 1 0 0 1 1 1 1 Cornifin (SPRR) family Iron_permease PF04120.7 GAM18700.1 - 0.1 12.1 0.3 0.26 10.8 0.2 1.7 1 0 0 1 1 1 0 Low affinity iron permease MCD PF05292.6 GAM18701.1 - 6.9e-48 163.1 0.2 1e-23 83.6 0.0 2.1 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase (MCD) PRK PF00485.13 GAM18702.1 - 1.4e-49 168.2 0.1 1.7e-49 168.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 GAM18702.1 - 1.3e-10 41.6 0.0 2.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM18702.1 - 1.6e-07 32.1 0.1 2.8e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 GAM18702.1 - 3.4e-06 26.8 0.1 0.0011 18.7 0.0 3.0 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Cytidylate_kin2 PF13189.1 GAM18702.1 - 0.00018 21.4 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.1 GAM18702.1 - 0.00052 19.9 0.0 0.00084 19.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM18702.1 - 0.00087 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 GAM18702.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family CoaE PF01121.15 GAM18702.1 - 0.0015 17.9 0.0 0.089 12.1 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase Spore_II_R PF09551.5 GAM18702.1 - 0.0027 17.7 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein R (spore_II_R) Zeta_toxin PF06414.7 GAM18702.1 - 0.0055 15.8 0.0 0.0076 15.3 0.0 1.6 1 1 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 GAM18702.1 - 0.0086 15.9 0.2 0.035 13.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 GAM18702.1 - 0.013 15.1 0.1 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 NTPase ATP-synt_ab PF00006.20 GAM18702.1 - 0.014 14.8 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain APS_kinase PF01583.15 GAM18702.1 - 0.015 15.0 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.1 GAM18702.1 - 0.022 14.7 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 GAM18702.1 - 0.025 14.1 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 GAM18702.1 - 0.027 13.8 0.1 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase TrwB_AAD_bind PF10412.4 GAM18702.1 - 0.033 12.7 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 GAM18702.1 - 0.038 13.6 0.0 0.043 13.5 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase KTI12 PF08433.5 GAM18702.1 - 0.046 12.9 0.0 0.096 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.1 GAM18702.1 - 0.052 13.5 0.0 0.096 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM18702.1 - 0.054 13.6 0.0 0.08 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM18702.1 - 0.13 11.9 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ADK PF00406.17 GAM18702.1 - 0.19 11.5 1.0 3.3 7.5 0.0 2.6 3 0 0 3 3 3 0 Adenylate kinase TPT PF03151.11 GAM18704.1 - 1.8e-17 63.4 11.4 1.8e-17 63.4 7.9 3.0 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 GAM18704.1 - 2.8e-08 33.8 39.0 6e-06 26.3 11.4 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 GAM18704.1 - 0.0055 15.6 28.9 0.011 14.7 20.1 1.5 1 1 0 1 1 1 1 UAA transporter family 7TMR-DISM_7TM PF07695.6 GAM18704.1 - 2.8 7.5 44.9 0.4 10.3 6.0 2.5 2 1 0 2 2 2 0 7TM diverse intracellular signalling SR-25 PF10500.4 GAM18704.1 - 6.7 6.1 20.1 1.1 8.6 3.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PRA1 PF03208.14 GAM18705.1 - 8.5e-27 93.3 2.3 1.1e-26 93.0 1.6 1.0 1 0 0 1 1 1 1 PRA1 family protein TMEMspv1-c74-12 PF11044.3 GAM18705.1 - 0.94 9.0 0.0 0.94 9.0 0.0 2.8 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein FERM_N PF09379.5 GAM18707.1 - 7.9e-06 25.8 0.8 0.013 15.5 0.0 3.1 3 0 0 3 3 3 2 FERM N-terminal domain TMF_DNA_bd PF12329.3 GAM18707.1 - 0.02 14.7 0.5 0.02 14.7 0.4 6.9 5 3 2 7 7 7 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.3 GAM18707.1 - 0.059 10.7 70.1 0.04 11.2 24.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TIG PF01833.19 GAM18708.1 - 2e-26 91.7 63.8 3.5e-07 30.1 4.7 6.9 6 1 1 7 7 7 6 IPT/TIG domain zf-B_box PF00643.19 GAM18709.1 - 3.2e-08 33.3 4.9 6.3e-08 32.3 3.4 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.1 GAM18709.1 - 4.9e-06 26.4 5.5 1.7 8.9 0.1 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 GAM18709.1 - 0.001 18.5 4.8 2.3 7.8 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM18709.1 - 0.0018 18.0 1.0 3 7.6 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM18709.1 - 0.11 12.6 0.5 41 4.5 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM18709.1 - 0.3 10.9 3.3 16 5.4 0.0 4.3 3 1 1 4 4 4 0 Kelch motif IBR PF01485.16 GAM18709.1 - 1.1 9.2 5.8 0.45 10.4 1.9 1.9 2 0 0 2 2 2 0 IBR domain RabGAP-TBC PF00566.13 GAM18710.1 - 2.5e-46 157.8 9.2 6e-46 156.6 6.4 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 GAM18710.1 - 0.0016 17.6 0.5 0.0077 15.4 0.4 2.3 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAM18710.1 - 0.0027 17.8 1.4 0.01 15.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM18710.1 - 0.083 12.8 4.2 0.13 12.1 0.1 3.4 3 1 1 4 4 4 0 EF-hand domain Med15 PF09606.5 GAM18711.1 - 0.077 11.1 113.5 0.032 12.4 55.3 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RhoGEF PF00621.15 GAM18712.1 - 3e-38 131.4 6.5 5e-38 130.7 4.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 GAM18712.1 - 0.088 12.7 0.2 0.088 12.7 0.1 3.5 2 1 2 4 4 4 0 Pleckstrin homology domain DUF4140 PF13600.1 GAM18713.1 - 0.0022 18.4 1.1 0.0022 18.4 0.8 1.9 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Herpes_BLRF2 PF05812.7 GAM18713.1 - 0.0061 16.3 4.9 0.024 14.4 3.3 2.1 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein IncA PF04156.9 GAM18713.1 - 0.017 14.7 2.1 0.017 14.7 1.4 2.0 2 0 0 2 2 2 0 IncA protein TSC22 PF01166.13 GAM18713.1 - 0.32 10.9 6.1 3.2 7.7 0.9 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF2630 PF10944.3 GAM18713.1 - 0.42 10.7 3.9 0.84 9.7 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) bZIP_1 PF00170.16 GAM18713.1 - 0.43 10.5 5.9 7.2 6.6 0.3 2.4 1 1 1 2 2 2 0 bZIP transcription factor Adenylsucc_synt PF00709.16 GAM18713.1 - 0.52 8.9 2.1 0.72 8.4 1.4 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase FlaC_arch PF05377.6 GAM18713.1 - 0.81 9.6 5.9 3.2 7.7 4.1 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.6 GAM18713.1 - 2.6 7.9 4.9 19 5.1 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.10 GAM18713.1 - 6.5 6.6 10.4 3 7.7 2.8 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Big_2 PF02368.13 GAM18714.1 - 7.1e-19 67.4 12.9 0.00016 21.4 0.0 9.4 10 1 0 10 10 10 4 Bacterial Ig-like domain (group 2) T2SS-T3SS_pil_N PF13629.1 GAM18714.1 - 6.1e-07 28.8 5.2 0.57 9.7 0.0 6.9 7 0 0 7 7 7 2 Pilus formation protein N terminal region BiPBP_C PF06832.7 GAM18714.1 - 1.2e-06 28.3 0.0 0.018 14.9 0.0 4.1 2 1 1 3 3 3 2 Penicillin-Binding Protein C-terminus Family DUF824 PF05688.6 GAM18714.1 - 0.11 12.1 4.8 0.33 10.6 0.0 3.6 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) UDP-g_GGTase PF06427.6 GAM18715.1 - 1.1e-54 184.9 0.7 3.9e-54 183.1 0.5 2.0 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 GAM18715.1 - 1.4e-07 31.1 0.4 4.1e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 PTR2 PF00854.16 GAM18716.1 - 3.4e-54 184.0 0.5 5.4e-54 183.3 0.3 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 GAM18716.1 - 6.2e-10 38.3 7.4 8.2e-10 37.9 5.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF308 PF03729.8 GAM18716.1 - 1.3 9.0 10.3 6.2 6.8 4.4 2.7 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) TPR_11 PF13414.1 GAM18717.1 - 1.6e-15 56.4 5.0 2.7e-15 55.7 2.4 2.1 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM18717.1 - 1.5e-10 40.1 7.3 3.1e-07 29.7 0.2 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM18717.1 - 3e-09 36.0 6.2 5.5e-05 22.7 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat RPAP3_C PF13877.1 GAM18717.1 - 3.2e-07 30.2 3.8 0.011 15.7 0.1 3.3 2 1 1 3 3 3 2 Potential Monad-binding region of RPAP3 TPR_19 PF14559.1 GAM18717.1 - 0.0018 18.5 3.2 0.0092 16.2 1.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM18717.1 - 0.0025 17.6 2.4 0.54 10.1 0.3 2.6 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 GAM18717.1 - 0.0044 17.6 3.2 0.49 11.1 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM18717.1 - 0.016 14.9 0.9 0.072 12.9 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18717.1 - 0.016 14.9 5.2 0.02 14.6 0.3 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM18717.1 - 0.019 15.1 3.8 0.1 12.8 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM18717.1 - 0.044 13.7 3.4 0.43 10.5 2.4 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM18717.1 - 0.075 12.8 0.0 0.6 10.0 0.0 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.7 GAM18717.1 - 0.35 10.7 5.2 0.73 9.6 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GARS_A PF01071.14 GAM18718.1 - 2.5e-74 249.0 0.0 4.2e-74 248.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_C PF02843.11 GAM18718.1 - 9.9e-26 89.7 0.6 1.4e-24 86.0 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain Ribosomal_L7Ae PF01248.21 GAM18718.1 - 1.7e-25 88.3 0.1 3.7e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AIRS_C PF02769.17 GAM18718.1 - 6.5e-23 81.4 0.0 2.3e-22 79.6 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAM18718.1 - 1.4e-16 60.4 1.1 4.9e-16 58.7 0.4 2.2 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain GARS_N PF02844.10 GAM18718.1 - 9.9e-15 54.8 0.1 3.8e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain ATP-grasp_4 PF13535.1 GAM18718.1 - 1.2e-10 41.4 0.0 4.8e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 GAM18718.1 - 5.3e-07 29.1 0.0 1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAM18718.1 - 2.3e-06 27.0 0.1 5.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 GAM18718.1 - 2.8e-06 26.3 0.0 4.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 GAM18718.1 - 1.8e-05 24.2 0.0 7.8e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAM18718.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 GAM18718.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus LRR_4 PF12799.2 GAM18719.1 - 1.4e-07 30.9 7.0 0.0016 18.0 0.7 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 GAM18719.1 - 3.3e-07 30.0 0.5 7.8e-07 28.8 0.4 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 GAM18719.1 - 1.7e-06 27.6 3.3 0.00032 20.3 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAM18719.1 - 0.0017 18.0 3.4 3.9 7.8 0.0 4.3 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 GAM18719.1 - 0.13 12.5 9.0 6.4 7.4 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat DUF4407 PF14362.1 GAM18719.1 - 0.54 9.1 5.1 1 8.2 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOBP PF15279.1 GAM18719.1 - 0.57 10.5 7.5 0.82 10.0 5.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PBP_sp32 PF07222.7 GAM18719.1 - 1.8 7.6 8.4 2.9 7.0 5.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 GAM18719.1 - 9.1 4.9 15.2 14 4.2 10.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mucin PF01456.12 GAM18720.1 - 0.2 11.3 11.2 0.27 11.0 7.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 GAM18720.1 - 0.56 9.3 7.5 0.78 8.9 5.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.17 GAM18721.1 - 7.2e-61 201.7 0.0 1.6e-21 75.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM18721.1 - 1.8e-37 127.1 0.0 3e-12 46.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM18721.1 - 1.9e-25 88.4 0.0 1e-07 31.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM18721.1 - 3.3e-05 23.5 0.7 0.21 11.3 0.0 3.3 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 GAM18721.1 - 4.8e-05 23.1 0.0 0.031 14.1 0.0 2.8 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 GAM18721.1 - 0.11 12.2 0.0 21 4.9 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 GAM18721.1 - 0.47 8.8 30.3 0.054 11.9 15.2 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CBM49 PF09478.5 GAM18722.1 - 2.7e-06 27.3 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 UQ_con PF00179.21 GAM18723.1 - 6.5e-38 129.3 0.1 1.3e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 GAM18723.1 - 0.0057 16.3 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 GAM18723.1 - 0.021 14.7 0.9 0.034 14.0 0.6 1.5 1 1 0 1 1 1 0 RWD domain DUF3138 PF11336.3 GAM18723.1 - 0.3 9.2 3.1 0.41 8.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3584 PF12128.3 GAM18726.1 - 0.02 12.2 18.5 0.023 12.0 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Calici_MSP PF05752.6 GAM18726.1 - 0.04 13.5 1.1 0.04 13.5 0.8 2.5 1 1 2 3 3 2 0 Calicivirus minor structural protein DUF4407 PF14362.1 GAM18726.1 - 0.06 12.3 14.1 0.076 11.9 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TACC PF05010.9 GAM18726.1 - 0.063 13.0 8.7 0.076 12.7 6.1 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Syntaxin PF00804.20 GAM18726.1 - 0.07 13.2 15.1 0.71 10.0 1.0 2.2 1 1 1 2 2 2 0 Syntaxin Enkurin PF13864.1 GAM18726.1 - 0.097 12.8 6.7 0.18 11.9 0.8 2.4 1 1 1 2 2 2 0 Calmodulin-binding DUF1212 PF06738.7 GAM18726.1 - 0.14 11.5 0.2 0.2 11.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Phlebovirus_NSM PF07246.6 GAM18726.1 - 0.19 10.8 2.1 0.23 10.6 1.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FlaC_arch PF05377.6 GAM18726.1 - 0.21 11.5 3.4 9.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Not3 PF04065.10 GAM18726.1 - 0.24 10.6 10.1 0.31 10.2 7.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.6 GAM18726.1 - 0.25 9.9 10.3 0.38 9.3 7.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 GAM18726.1 - 0.27 10.9 12.2 0.51 9.9 8.5 1.4 1 1 0 1 1 1 0 Mnd1 family DUF29 PF01724.11 GAM18726.1 - 0.35 10.6 9.3 0.27 11.0 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF29 IncA PF04156.9 GAM18726.1 - 0.37 10.3 14.5 0.6 9.6 10.0 1.3 1 0 0 1 1 1 0 IncA protein Perilipin PF03036.11 GAM18726.1 - 0.46 9.2 10.1 0.57 8.9 7.0 1.0 1 0 0 1 1 1 0 Perilipin family DUF972 PF06156.8 GAM18726.1 - 0.52 10.6 10.1 0.41 11.0 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 GAM18726.1 - 0.9 7.3 4.9 1.2 6.8 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 GAM18726.1 - 1.1 8.9 14.5 0.54 9.9 1.8 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 AAA_13 PF13166.1 GAM18726.1 - 1.6 7.0 13.7 3.2 6.0 9.5 1.3 1 1 0 1 1 1 0 AAA domain HPPK PF01288.15 GAM18726.1 - 1.7 8.3 6.4 0.41 10.3 1.6 1.9 1 1 1 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF342 PF03961.8 GAM18726.1 - 2.1 6.6 9.5 3.5 5.9 6.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FliJ PF02050.11 GAM18726.1 - 2.2 8.3 30.5 0.035 14.1 12.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein MerR-DNA-bind PF09278.6 GAM18726.1 - 2.6 8.5 13.2 3.7 8.0 1.7 2.5 1 1 1 2 2 2 0 MerR, DNA binding DUF4200 PF13863.1 GAM18726.1 - 3 7.8 15.5 35 4.3 10.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Prefoldin PF02996.12 GAM18726.1 - 4 7.1 10.5 2 8.0 0.5 2.5 2 1 0 2 2 2 0 Prefoldin subunit Uds1 PF15456.1 GAM18726.1 - 4.2 7.3 10.5 17 5.3 6.9 1.8 1 1 1 2 2 2 0 Up-regulated During Septation DUF4140 PF13600.1 GAM18726.1 - 5.3 7.5 12.2 2.3 8.7 2.2 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 GAM18726.1 - 7.6 6.3 12.0 1.9e+02 1.7 8.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Syntaxin-6_N PF09177.6 GAM18726.1 - 9.5 6.6 10.9 17 5.8 4.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YlqD PF11068.3 GAM18726.1 - 9.7 6.2 25.3 0.29 11.1 11.7 1.9 1 1 1 2 2 2 0 YlqD protein Ricin_B_lectin PF00652.17 GAM18728.1 - 1.4e-06 28.2 0.8 1.2e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 GAM18728.1 - 1.5e-05 24.4 0.4 0.0046 16.3 0.0 2.9 1 1 2 3 3 3 2 Cytolethal distending toxin A/C family Endotoxin_N PF03945.9 GAM18729.1 - 7.1e-14 51.7 3.1 1.7e-13 50.4 2.1 1.5 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain SNF2_N PF00176.18 GAM18730.1 - 4e-70 235.9 1.1 1.1e-69 234.4 0.8 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 GAM18730.1 - 2e-21 75.3 9.3 5.6e-12 45.1 0.1 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 GAM18730.1 - 1.2e-14 53.8 0.0 5.1e-14 51.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 GAM18730.1 - 0.0057 16.6 0.0 16 5.6 0.0 4.3 4 0 0 4 4 4 1 Myb-like DNA-binding domain RhoGAP PF00620.22 GAM18731.1 - 0.0003 20.4 4.2 0.0022 17.6 0.3 2.8 3 0 0 3 3 3 2 RhoGAP domain VWA_2 PF13519.1 GAM18732.1 - 1.6e-12 47.8 0.0 2.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Mucin PF01456.12 GAM18732.1 - 0.57 9.9 14.2 0.14 11.9 3.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein PBP1_TM PF14812.1 GAM18732.1 - 2 8.8 5.5 2.1 8.7 0.6 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CBM49 PF09478.5 GAM18733.1 - 2.4e-14 53.1 0.2 5.8e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF1748 PF08520.5 GAM18734.1 - 3.6e-12 45.7 0.1 5e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Pex14_N PF04695.8 GAM18734.1 - 7.2 6.6 13.7 5.6e+02 0.5 9.5 2.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR_HSR1 PF01926.18 GAM18735.1 - 2.4e-15 56.5 0.0 4.4e-12 45.9 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM18735.1 - 3.9e-05 22.9 0.0 0.00079 18.7 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM18735.1 - 0.00045 19.4 0.3 0.0015 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 GAM18735.1 - 0.00054 19.4 0.2 0.8 9.1 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 GAM18735.1 - 0.057 13.9 0.0 0.057 13.9 0.0 3.3 3 1 1 4 4 4 0 Miro-like protein Dynamin_N PF00350.18 GAM18735.1 - 0.32 10.7 11.5 0.19 11.5 4.0 3.6 2 1 0 2 2 2 0 Dynamin family EF-hand_1 PF00036.27 GAM18738.1 - 7.3e-20 68.7 1.6 2.9e-05 23.0 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 GAM18738.1 - 1.5e-19 69.9 1.2 4.7e-14 52.2 0.9 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM18738.1 - 6.6e-17 59.8 1.0 3.9e-06 26.2 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM18738.1 - 2.1e-11 43.2 2.5 9.4e-08 31.5 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM18738.1 - 2.7e-10 39.0 3.2 0.001 18.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 GAM18738.1 - 2.2e-06 27.4 0.1 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 GAM18738.1 - 0.0045 17.0 0.0 0.02 14.9 0.0 1.8 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 GAM18738.1 - 0.018 15.0 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Ca2+ insensitive EF hand RRM_6 PF14259.1 GAM18739.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Orthopox_35kD PF02250.10 GAM18739.1 - 0.0068 15.7 0.2 1.5 8.0 0.0 2.3 2 0 0 2 2 2 2 35kD major secreted virus protein RRM_1 PF00076.17 GAM18739.1 - 0.0087 15.6 0.1 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF912 PF06024.7 GAM18739.1 - 2.1 8.4 8.0 5.4 7.1 1.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LRR_6 PF13516.1 GAM18740.1 - 1.9e-21 73.6 21.0 0.0046 16.8 0.0 8.2 7 0 0 7 7 7 7 Leucine Rich repeat LRR_7 PF13504.1 GAM18740.1 - 1.4e-11 42.6 1.7 1.3 9.5 0.0 7.6 7 0 0 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 GAM18740.1 - 2e-11 42.2 5.6 0.5 10.6 0.1 7.4 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_4 PF12799.2 GAM18740.1 - 7.2e-11 41.4 21.5 0.0035 16.9 0.3 6.4 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18740.1 - 4e-09 36.1 15.3 0.004 16.8 1.1 4.9 4 0 0 4 4 4 4 Leucine rich repeat Mt_ATP-synt_D PF05873.7 GAM18743.1 - 0.002 17.7 0.4 0.0023 17.6 0.3 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Vfa1 PF08432.5 GAM18743.1 - 0.022 14.8 6.0 0.027 14.4 4.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LRR_6 PF13516.1 GAM18745.1 - 2.4e-11 42.4 23.9 0.095 12.8 0.0 11.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.2 GAM18745.1 - 1e-07 31.4 13.6 1.4 8.6 0.1 8.3 7 2 1 8 8 8 3 Leucine Rich repeats (2 copies) Peptidase_C36 PF05415.6 GAM18745.1 - 0.017 14.9 0.1 0.045 13.6 0.1 1.7 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase LRR_7 PF13504.1 GAM18745.1 - 0.28 11.5 9.9 2e+02 2.9 0.0 8.4 9 0 0 9 9 9 0 Leucine rich repeat HSP20 PF00011.16 GAM18746.1 - 1.6e-12 47.1 0.0 6.1e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family G-alpha PF00503.15 GAM18747.1 - 2.9e-97 325.7 0.2 3.7e-97 325.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM18747.1 - 1.2e-13 50.7 0.0 2.4e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM18747.1 - 0.0035 16.5 0.0 2 7.4 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM18747.1 - 0.068 13.1 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 GAM18747.1 - 0.082 13.4 0.0 0.94 9.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 GAM18747.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 GAM18748.1 - 0 1168.1 3.8 0 1167.9 2.6 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3848 PF12959.2 GAM18748.1 - 0.32 10.9 2.5 0.83 9.6 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3848) Pkinase PF00069.20 GAM18749.1 - 2.1e-72 243.3 0.0 2.6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18749.1 - 2.1e-37 128.6 0.0 2.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 GAM18749.1 - 9.4e-20 70.7 0.0 2.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.19 GAM18749.1 - 4.9e-09 36.5 0.1 1e-08 35.5 0.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_11 PF15413.1 GAM18749.1 - 1.4e-08 34.9 0.6 6.5e-07 29.5 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 GAM18749.1 - 6.6e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM18749.1 - 0.00011 22.1 0.8 0.00062 19.7 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 GAM18749.1 - 0.00066 18.7 0.0 0.0063 15.5 0.0 2.0 1 1 0 2 2 2 1 Kinase-like PH_6 PF15406.1 GAM18749.1 - 0.0068 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM18749.1 - 0.01 15.9 0.5 0.048 13.8 0.0 2.3 2 2 0 2 2 2 0 Pleckstrin homology domain APH PF01636.18 GAM18749.1 - 0.051 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM18749.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NST1 PF13945.1 GAM18750.1 - 7.4e-48 163.1 29.8 7.4e-48 163.1 20.6 6.3 3 2 3 7 7 7 1 Salt tolerance down-regulator NicO PF03824.11 GAM18750.1 - 0.75 9.0 1.8 1.3 8.2 1.3 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF3439 PF11921.3 GAM18750.1 - 4.3 7.1 7.4 0.52 10.0 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UDPGP PF01704.13 GAM18751.1 - 7.8e-168 558.3 2.2 9e-168 558.1 1.5 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PP-binding_2 PF14573.1 GAM18751.1 - 0.018 15.0 0.0 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Acyl-carrier FNIP PF05725.7 GAM18752.1 - 6.7e-72 237.2 34.9 2.9e-13 49.5 0.2 8.5 6 1 2 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 GAM18752.1 - 1.1e-06 28.5 12.0 12 5.8 0.0 8.1 4 2 4 8 8 8 5 Protein of unknown function (DUF1769) PseudoU_synth_2 PF00849.17 GAM18753.1 - 1.1e-30 106.6 3.1 2.4e-30 105.5 0.0 2.7 3 0 0 3 3 3 1 RNA pseudouridylate synthase TGS PF02824.16 GAM18753.1 - 0.027 14.2 0.3 0.76 9.6 0.1 2.9 3 0 0 3 3 3 0 TGS domain S4 PF01479.20 GAM18753.1 - 0.095 12.1 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 S4 domain CAML PF14963.1 GAM18753.1 - 1.6 8.0 11.9 3.4 6.9 8.2 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Ndc1_Nup PF09531.5 GAM18753.1 - 2.2 6.5 7.9 3.3 6.0 5.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L29e PF01779.12 GAM18755.1 - 5.7e-19 67.7 11.3 5.7e-19 67.7 7.8 2.2 2 0 0 2 2 2 1 Ribosomal L29e protein family DUF966 PF06136.8 GAM18755.1 - 0.16 11.3 3.6 0.17 11.3 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Iso_dh PF00180.15 GAM18756.1 - 9.6e-77 258.2 0.0 1.1e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhoU_div PF01865.11 GAM18756.1 - 0.057 12.5 0.0 8.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF47 RabGAP-TBC PF00566.13 GAM18757.1 - 2.2e-56 190.7 0.4 2.2e-56 190.7 0.3 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RNase_P_p30 PF01876.11 GAM18758.1 - 2.7e-35 120.8 0.1 3.9e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Colicin_D PF11429.3 GAM18760.1 - 0.03 14.4 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Colicin D Antimicrobial14 PF08109.6 GAM18760.1 - 0.031 14.0 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 Lactocin 705 family Myosin_tail_1 PF01576.14 GAM18760.1 - 0.14 9.8 0.2 0.16 9.6 0.1 1.0 1 0 0 1 1 1 0 Myosin tail IncA PF04156.9 GAM18761.1 - 0.0038 16.8 18.1 0.066 12.8 3.5 3.2 1 1 2 3 3 3 2 IncA protein Myosin_tail_1 PF01576.14 GAM18761.1 - 0.004 14.9 20.6 0.0049 14.6 6.6 2.2 1 1 0 1 1 1 1 Myosin tail APG6 PF04111.7 GAM18761.1 - 0.035 13.1 11.8 0.061 12.3 8.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 GAM18761.1 - 0.061 13.0 4.0 0.25 11.0 2.8 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GLE1 PF07817.8 GAM18761.1 - 0.076 11.9 3.3 0.13 11.2 2.3 1.3 1 0 0 1 1 1 0 GLE1-like protein Spc7 PF08317.6 GAM18761.1 - 0.1 11.2 13.3 0.21 10.2 9.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.16 GAM18761.1 - 0.19 11.1 15.5 2.6 7.4 9.8 2.4 1 1 0 1 1 1 0 Intermediate filament protein GAS PF13851.1 GAM18761.1 - 0.24 10.5 17.3 0.84 8.7 12.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 GAM18761.1 - 0.29 10.2 2.1 0.44 9.6 1.5 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein T4SS PF07996.6 GAM18761.1 - 0.8 9.5 11.1 0.16 11.8 5.3 1.5 2 0 0 2 2 1 0 Type IV secretion system proteins Rootletin PF15035.1 GAM18761.1 - 1 9.3 19.8 0.026 14.4 7.9 2.5 4 0 0 4 4 4 0 Ciliary rootlet component, centrosome cohesion Bap31 PF05529.7 GAM18761.1 - 1.2 8.5 14.0 2.2 7.7 2.2 2.6 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 GAM18761.1 - 1.5 7.6 13.8 10 4.9 9.3 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 LMP PF04778.7 GAM18761.1 - 3.1 7.5 17.9 11 5.6 12.4 2.3 1 1 0 1 1 1 0 LMP repeated region CENP-F_leu_zip PF10473.4 GAM18761.1 - 4.2 7.2 22.6 0.023 14.5 5.3 2.7 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 GAM18761.1 - 4.9 7.4 11.3 62 3.9 7.8 2.2 1 1 0 1 1 1 0 Striatin family HOOK PF05622.7 GAM18761.1 - 5 4.8 18.1 3.2 5.4 3.0 2.1 1 1 1 2 2 2 0 HOOK protein ADIP PF11559.3 GAM18761.1 - 8.5 6.2 20.7 0.76 9.6 6.8 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_lysis PF03245.8 GAM18761.1 - 9.7 6.2 10.4 4 7.4 2.6 2.8 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein RRM_6 PF14259.1 GAM18763.1 - 5.2e-11 42.3 0.2 2.8e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM18763.1 - 2.2e-09 36.8 1.0 4.2e-05 23.0 0.1 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM18763.1 - 5.6e-06 26.1 0.1 0.086 12.7 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPI_Ypi1 PF07491.6 GAM18764.1 - 6.4e-22 76.9 7.9 9.8e-22 76.3 5.3 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor RXT2_N PF08595.6 GAM18764.1 - 0.045 13.5 1.5 0.057 13.2 1.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Big_4 PF07532.6 GAM18764.1 - 0.11 12.0 2.8 0.19 11.3 2.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Dicty_REP PF05086.7 GAM18764.1 - 0.19 9.4 4.7 0.2 9.3 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 GAM18764.1 - 0.32 10.4 4.9 0.62 9.5 3.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 GAM18764.1 - 2.1 8.2 8.8 2 8.2 5.5 1.3 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ras PF00071.17 GAM18765.1 - 1.3e-61 206.6 0.6 1.6e-61 206.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM18765.1 - 6.4e-21 75.0 0.0 1.2e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM18765.1 - 6.9e-14 51.4 0.2 8.4e-14 51.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM18765.1 - 8.8e-08 32.1 0.1 1.6e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM18765.1 - 1.2e-06 28.0 0.2 4.4e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAM18765.1 - 0.00011 22.3 0.1 0.00075 19.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 GAM18765.1 - 0.00035 19.7 0.1 0.0005 19.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM18765.1 - 0.00045 19.4 0.0 0.0008 18.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 GAM18765.1 - 0.00051 19.2 0.2 0.00064 18.8 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 GAM18765.1 - 0.003 16.7 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 GAM18765.1 - 0.0059 15.8 0.5 0.047 12.9 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 GAM18765.1 - 0.0094 15.8 0.1 0.024 14.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM18765.1 - 0.016 15.2 0.4 0.085 12.8 0.4 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 GAM18765.1 - 0.022 14.7 0.4 0.32 10.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM18765.1 - 0.022 15.0 0.3 0.036 14.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 GAM18765.1 - 0.025 14.0 0.0 0.09 12.2 0.0 1.8 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_32 PF13654.1 GAM18765.1 - 0.04 12.5 0.4 1.4 7.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM18765.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cofilin_ADF PF00241.15 GAM18766.1 - 6e-05 22.9 0.0 6.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Fer2_3 PF13085.1 GAM18767.1 - 3.3e-32 110.5 0.0 5.3e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.1 GAM18767.1 - 3.8e-09 36.4 1.9 3.8e-09 36.4 1.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 GAM18767.1 - 4.9e-09 36.3 2.4 4.9e-09 36.3 1.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAM18767.1 - 6.9e-05 23.1 3.1 0.06 13.7 0.2 2.6 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 GAM18767.1 - 0.0001 22.4 5.7 0.065 13.5 0.6 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAM18767.1 - 0.00015 21.4 3.1 0.00015 21.4 2.2 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 GAM18767.1 - 0.015 15.0 5.2 0.023 14.4 0.3 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 GAM18767.1 - 0.41 11.0 13.5 1.5 9.2 7.4 2.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Zw10 PF06248.8 GAM18769.1 - 2.2e-17 62.4 21.4 3.6e-11 41.9 1.1 2.6 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Secretin_N_2 PF07655.8 GAM18769.1 - 5.7 7.3 19.8 23 5.4 13.7 2.1 1 0 0 1 1 1 0 Secretin N-terminal domain Vps26 PF03643.10 GAM18770.1 - 6.7e-90 300.5 10.2 9.5e-87 290.2 3.6 2.0 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAM18770.1 - 1.9e-05 24.5 1.0 0.27 11.0 0.0 3.3 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF4506 PF14958.1 GAM18770.1 - 0.033 13.7 0.6 2.8 7.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4506) tRNA-synt_2 PF00152.15 GAM18771.1 - 1e-117 392.6 0.0 1.6e-117 392.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM18771.1 - 3.1e-10 39.7 0.0 6.8e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GAD PF02938.9 GAM18771.1 - 1e-08 35.2 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 GAD domain tRNA-synt_2b PF00587.20 GAM18771.1 - 0.0024 17.4 0.5 0.26 10.8 0.1 2.5 1 1 1 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 GAM18771.1 - 0.013 14.6 0.1 0.076 12.1 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) tify PF06200.9 GAM18772.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 tify domain Med24_N PF11277.3 GAM18772.1 - 0.03 11.8 0.2 0.04 11.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Sporozoite_P67 PF05642.6 GAM18772.1 - 0.035 11.9 8.7 0.048 11.5 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-CCCH PF00642.19 GAM18774.1 - 3.3e-12 45.7 39.6 0.0003 20.3 0.2 5.6 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 GAM18774.1 - 2.7e-07 30.1 11.4 0.00054 19.7 1.4 3.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 GAM18774.1 - 0.023 14.1 17.6 0.093 12.2 2.4 4.1 3 1 1 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.1 GAM18774.1 - 0.027 14.1 6.4 0.099 12.3 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH_2 PF14608.1 GAM18774.1 - 0.081 12.9 40.1 1.9 8.5 3.0 6.5 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type Ceramidase PF05875.7 GAM18775.1 - 2.5e-58 197.2 8.2 3e-58 197.0 5.7 1.0 1 0 0 1 1 1 1 Ceramidase DUF2254 PF10011.4 GAM18775.1 - 0.12 10.8 1.5 0.18 10.2 0.9 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) DDHD PF02862.12 GAM18776.1 - 1.4e-27 97.0 0.0 2.4e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.9 GAM18776.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF727 PF05303.7 GAM18777.1 - 5.7e-10 38.9 0.0 6.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) PNTB PF02233.11 GAM18777.1 - 0.05 12.3 0.0 0.058 12.1 0.0 1.0 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit PARP PF00644.15 GAM18778.1 - 0.0004 19.8 0.2 0.00083 18.8 0.1 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Cellulase PF00150.13 GAM18779.1 - 1e-28 100.3 2.8 2.6e-28 99.0 1.9 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 GAM18779.1 - 0.0011 18.1 0.2 0.0024 17.0 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase PolyA_pol PF01743.15 GAM18780.1 - 2.6e-28 98.7 0.1 2.6e-28 98.7 0.1 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAM18780.1 - 8.3e-06 25.2 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 GAM18780.1 - 0.0012 18.7 0.1 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative Ribosomal_L23 PF00276.15 GAM18781.1 - 3.9e-16 58.7 1.4 3.9e-16 58.7 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 GAM18781.1 - 2.6e-15 56.1 11.4 2.6e-15 56.1 7.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L18p PF00861.17 GAM18781.1 - 0.1 12.7 3.6 0.28 11.3 0.1 2.3 2 1 0 2 2 2 0 Ribosomal L18p/L5e family Ribosomal_L30_N PF08079.7 GAM18781.1 - 0.99 9.4 5.6 2.7 8.0 3.9 1.7 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain G-patch PF01585.18 GAM18782.1 - 4.5e-08 32.7 1.8 1.6e-07 31.0 1.2 2.0 1 0 0 1 1 1 1 G-patch domain SEP PF08059.8 GAM18783.1 - 1e-25 89.8 1.3 1.9e-25 88.9 0.1 2.1 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.1 GAM18783.1 - 1.5e-14 53.1 0.2 2.9e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 GAM18783.1 - 3e-14 52.8 0.0 5.9e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 GAM18783.1 - 0.025 13.9 1.6 0.41 9.9 0.0 2.7 2 1 0 2 2 2 0 Spt20 family Paramyxo_C PF01692.13 GAM18783.1 - 0.12 12.0 2.4 0.17 11.4 0.1 2.2 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c Coiled PF05710.7 GAM18785.1 - 5.1e-05 23.6 7.3 6.1e-05 23.4 5.0 1.1 1 0 0 1 1 1 1 Coiled coil MSSP PF03940.8 GAM18785.1 - 0.021 14.2 11.7 0.021 14.2 8.1 2.3 1 1 1 2 2 2 0 Male specific sperm protein Reo_sigmaC PF04582.7 GAM18787.1 - 0.015 14.4 29.5 0.037 13.2 2.7 3.9 1 1 1 4 4 4 0 Reovirus sigma C capsid protein Mod_r PF07200.8 GAM18787.1 - 0.19 11.6 75.8 0.041 13.7 6.8 6.0 5 1 0 5 5 5 0 Modifier of rudimentary (Mod(r)) protein Hemerythrin PF01814.18 GAM18787.1 - 0.72 10.0 23.1 2.5 8.2 0.6 5.3 3 3 3 6 6 6 0 Hemerythrin HHE cation binding domain Pox_A_type_inc PF04508.7 GAM18787.1 - 1.7 8.6 28.5 0.48 10.3 1.8 7.9 7 1 1 8 8 8 0 Viral A-type inclusion protein repeat GTA_TIM PF13547.1 GAM18788.1 - 0.0007 18.6 1.8 0.026 13.5 0.8 2.9 1 1 1 2 2 2 2 GTA TIM-barrel-like domain Cellulase PF00150.13 GAM18788.1 - 0.0013 18.0 1.0 0.002 17.4 0.7 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PWWP PF00855.12 GAM18789.1 - 6.7e-14 51.8 0.8 6.7e-14 51.8 0.5 3.1 4 0 0 4 4 4 1 PWWP domain BTB PF00651.26 GAM18790.1 - 2.5e-21 75.7 1.8 3.5e-19 68.8 0.2 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 GAM18790.1 - 1.3e-09 37.8 2.1 4.7e-07 29.5 0.7 3.3 2 1 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.20 GAM18790.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain Cas_VVA1548 PF09652.5 GAM18790.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative CRISPR-associated protein (Cas_VVA1548) DNA_pol_A PF00476.15 GAM18791.1 - 5.3e-69 232.6 1.4 4.3e-58 196.7 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family A TMEM210 PF15195.1 GAM18791.1 - 0.14 12.2 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 TMEM210 family DUF3439 PF11921.3 GAM18791.1 - 9.7 5.9 16.7 3.1 7.5 6.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ras PF00071.17 GAM18793.1 - 1.4e-28 99.3 0.2 1.8e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM18793.1 - 1.1e-15 58.1 0.0 3.1e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM18793.1 - 2.6e-15 56.0 0.1 3.3e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM18793.1 - 3.8e-09 36.2 0.0 1.9e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM18793.1 - 1.6e-07 30.7 0.0 2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM18793.1 - 0.00027 20.8 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM18793.1 - 0.038 13.2 0.1 0.13 11.5 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.1 GAM18793.1 - 0.042 12.8 1.0 0.061 12.3 0.6 1.3 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M41 PF01434.13 GAM18794.1 - 3.4e-68 229.2 4.8 1e-67 227.7 3.3 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAM18794.1 - 2.9e-40 137.5 0.2 1.4e-39 135.3 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM18794.1 - 2.1e-05 23.6 0.0 4.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM18794.1 - 5.8e-05 23.2 0.7 0.038 14.1 0.2 3.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM18794.1 - 6.1e-05 22.7 0.1 0.0003 20.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM18794.1 - 0.00017 21.6 0.2 0.043 13.7 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 GAM18794.1 - 0.00092 18.0 0.0 0.002 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 GAM18794.1 - 0.0021 17.2 3.0 0.19 10.8 0.1 3.3 2 1 1 3 3 3 1 KaiC AAA_17 PF13207.1 GAM18794.1 - 0.0027 18.5 0.0 0.009 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM18794.1 - 0.0046 16.6 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 GAM18794.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 GAM18794.1 - 0.0095 15.3 0.5 1 8.7 0.1 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAM18794.1 - 0.015 14.7 0.1 0.037 13.4 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 GAM18794.1 - 0.015 14.7 0.1 0.064 12.7 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 GAM18794.1 - 0.016 14.8 0.2 0.52 9.9 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 GAM18794.1 - 0.026 14.5 0.0 0.087 12.8 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_2 PF07724.9 GAM18794.1 - 0.033 14.0 0.0 0.17 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 GAM18794.1 - 0.034 13.3 0.1 0.082 12.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAM18794.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM18794.1 - 0.043 13.6 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAM18794.1 - 0.044 14.0 0.7 0.21 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 GAM18794.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Beta_helix PF13229.1 GAM18795.1 - 2.1e-43 147.8 81.4 6.5e-23 81.2 19.9 4.3 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.8 GAM18795.1 - 6.6e-29 100.7 65.5 1.8e-15 56.7 13.7 4.3 3 1 2 5 5 5 3 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.2 GAM18795.1 - 2.6e-06 27.7 37.7 0.00017 21.7 7.2 3.6 1 1 2 3 3 3 2 Pectate lyase superfamily protein F-box PF00646.28 GAM18795.1 - 1.6e-05 24.3 0.9 4e-05 23.1 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM18795.1 - 5.3e-05 22.8 0.8 0.00012 21.6 0.6 1.5 1 0 0 1 1 1 1 F-box-like ATP_synt_I PF03899.10 GAM18796.1 - 0.02 15.0 12.9 0.038 14.1 2.3 2.3 1 1 1 2 2 2 0 ATP synthase I chain Neugrin PF06413.6 GAM18797.1 - 2.9e-10 40.3 1.3 2.9e-10 40.3 0.9 3.1 2 2 1 3 3 3 1 Neugrin MRP-L20 PF12824.2 GAM18797.1 - 1.5e-05 24.9 7.2 1.5e-05 24.9 5.0 2.9 2 1 0 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Dynactin_p62 PF05502.8 GAM18798.1 - 6.8e-45 153.7 22.6 8.7e-45 153.3 15.3 1.5 1 1 0 1 1 1 1 Dynactin p62 family Fe-S_biosyn PF01521.15 GAM18799.1 - 2.4e-15 56.4 0.0 3.2e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Voltage_CLC PF00654.15 GAM18800.1 - 6.4e-106 354.3 21.6 6.7e-105 351.0 12.0 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 GAM18800.1 - 2.8e-22 78.2 0.1 5.6e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.4 GAM18800.1 - 6.3 7.0 9.5 0.24 11.5 0.7 2.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence TSP_3 PF02412.13 GAM18801.1 - 3.1 7.3 28.0 11 5.6 6.9 4.3 1 1 2 3 3 3 0 Thrombospondin type 3 repeat TSP_3 PF02412.13 GAM18802.1 - 0.0045 16.4 39.0 0.3 10.5 0.4 5.8 1 1 4 5 5 5 4 Thrombospondin type 3 repeat DUF4525 PF15027.1 GAM18803.1 - 0.7 9.4 3.9 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF992 PF06186.6 GAM18804.1 - 0.14 11.4 0.1 0.78 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF992) HATPase_c PF02518.21 GAM18805.1 - 1e-29 102.4 0.1 2.5e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM18805.1 - 8e-24 83.8 0.1 5.4e-23 81.1 0.0 2.5 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAM18805.1 - 1.5e-15 56.9 0.0 3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 GAM18805.1 - 0.007 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3311 PF11755.3 GAM18806.1 - 0.0033 16.9 4.5 0.0033 16.9 3.1 3.5 5 1 0 5 5 5 1 Protein of unknown function (DUF3311) Methyltransf_10 PF05971.7 GAM18807.1 - 1.9e-53 181.5 0.6 7.6e-51 173.0 0.1 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF890) MTS PF05175.9 GAM18807.1 - 6e-08 32.2 0.9 1.2e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM18807.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM18807.1 - 0.00021 21.8 0.0 0.00053 20.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAM18807.1 - 0.00031 20.3 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 GAM18807.1 - 0.0015 17.6 0.1 0.0015 17.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAM18807.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF633 PF04816.7 GAM18807.1 - 0.018 14.3 0.1 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF633) TPR_11 PF13414.1 GAM18808.1 - 6.8e-20 70.4 2.8 4.1e-14 51.9 1.0 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM18808.1 - 6.9e-16 57.1 4.3 5.2e-05 22.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM18808.1 - 1.7e-13 49.3 1.3 0.00083 19.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18808.1 - 6.2e-08 31.8 6.0 0.001 18.6 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-C3HC4 PF00097.20 GAM18808.1 - 4.3e-07 29.4 14.9 1.2e-06 28.0 10.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM18808.1 - 5.5e-07 29.3 14.5 1.3e-06 28.1 10.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM18808.1 - 6.2e-07 29.0 14.8 1.5e-06 27.8 10.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM18808.1 - 7.9e-07 28.9 15.3 1.8e-06 27.8 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM18808.1 - 2.6e-06 27.0 11.4 6.1e-06 25.8 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Apc3 PF12895.2 GAM18808.1 - 3.4e-06 27.1 2.4 3.4e-06 27.1 1.6 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAM18808.1 - 4.7e-06 26.4 1.1 9.1e-05 22.3 0.5 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM18808.1 - 9.3e-06 25.4 0.3 0.031 14.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 GAM18808.1 - 5e-05 22.2 0.3 5e-05 22.2 0.2 1.6 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 zf-C3HC4_4 PF15227.1 GAM18808.1 - 0.00036 20.3 16.2 0.00081 19.2 11.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TPR_16 PF13432.1 GAM18808.1 - 0.00075 20.1 0.1 0.066 13.9 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM18808.1 - 0.0021 18.3 0.0 0.54 10.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-RING_UBOX PF13445.1 GAM18808.1 - 0.0084 15.8 4.7 0.0084 15.8 3.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAM18808.1 - 0.015 15.0 9.2 0.029 14.1 6.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_9 PF13371.1 GAM18808.1 - 0.037 13.8 0.5 0.075 12.8 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM18808.1 - 0.043 14.4 0.0 5 8.0 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat zf-RING_4 PF14570.1 GAM18808.1 - 0.07 12.7 12.7 0.24 11.0 8.8 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_6 PF13174.1 GAM18808.1 - 0.11 12.9 3.4 7.7 7.2 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RasGAP PF00616.14 GAM18809.1 - 1.8e-37 128.9 0.4 1.8e-37 128.9 0.3 2.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAM18809.1 - 4.1e-24 84.8 4.2 4.1e-24 84.8 2.9 2.1 3 0 0 3 3 3 1 RasGAP C-terminus MCM_N PF14551.1 GAM18809.1 - 0.0057 17.1 2.9 0.011 16.2 0.1 3.0 2 1 0 2 2 2 1 MCM N-terminal domain Sec63 PF02889.11 GAM18810.1 - 2.1e-152 506.7 9.4 3.1e-90 302.5 1.4 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAM18810.1 - 5.3e-57 191.9 1.3 3e-30 104.9 0.5 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 GAM18810.1 - 8.3e-23 81.1 1.4 2e-11 44.0 0.2 3.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM18810.1 - 2.3e-17 62.6 0.0 3.6e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAM18810.1 - 2.4e-07 30.9 0.8 0.014 15.5 0.1 3.6 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 GAM18810.1 - 2.8e-06 26.7 0.1 0.072 12.3 0.1 2.8 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.24 GAM18810.1 - 4.6e-05 23.6 2.1 0.12 12.5 0.0 4.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 GAM18810.1 - 0.0001 21.8 0.0 0.001 18.6 0.0 2.4 2 1 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 GAM18810.1 - 0.00031 19.7 0.0 0.96 8.2 0.0 2.9 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 GAM18810.1 - 0.00093 18.6 0.1 0.8 9.0 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein Erg28 PF03694.8 GAM18811.1 - 6.4e-31 106.6 5.3 7.2e-31 106.4 3.6 1.0 1 0 0 1 1 1 1 Erg28 like protein SUR7 PF06687.7 GAM18811.1 - 0.12 11.9 6.3 0.14 11.7 4.3 1.2 1 0 0 1 1 1 0 SUR7/PalI family LIM PF00412.17 GAM18812.1 - 9e-26 89.7 35.8 1e-08 35.1 5.0 3.3 3 0 0 3 3 3 3 LIM domain C1_1 PF00130.17 GAM18812.1 - 0.25 11.0 24.3 0.28 10.9 1.2 3.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rieske PF00355.21 GAM18812.1 - 0.6 9.7 13.5 2.9 7.5 0.7 3.5 3 0 0 3 3 3 0 Rieske [2Fe-2S] domain PHF5 PF03660.9 GAM18812.1 - 2.5 8.1 20.6 1.4 8.9 0.7 3.3 3 0 0 3 3 3 0 PHF5-like protein MTHFR_C PF12225.3 GAM18812.1 - 7.4 6.1 18.8 5 6.6 0.2 4.2 3 2 1 4 4 4 0 Methylene-tetrahydrofolate reductase C terminal Peptidase_S28 PF05577.7 GAM18813.1 - 1.6e-92 310.4 6.1 1.9e-92 310.1 4.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAM18813.1 - 1.7e-07 31.3 0.0 3.7e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM18813.1 - 8.9e-05 22.1 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM18813.1 - 0.011 15.4 0.1 0.022 14.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family TIG PF01833.19 GAM18814.1 - 1.6e-13 50.4 26.1 7.7e-07 29.0 0.6 6.2 5 1 1 6 6 6 4 IPT/TIG domain Lectin_C PF00059.16 GAM18814.1 - 0.0013 19.3 2.4 0.0013 19.3 1.7 2.2 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.8 GAM18814.1 - 0.0066 16.5 6.4 0.017 15.3 4.5 1.7 1 0 0 1 1 1 1 EGF-like domain DUF872 PF05915.7 GAM18814.1 - 0.013 15.3 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) hEGF PF12661.2 GAM18814.1 - 0.019 15.0 1.0 0.08 13.0 0.7 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.19 GAM18814.1 - 0.47 10.4 2.5 1.2 9.0 1.7 1.7 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Baculo_PEP_C PF04513.7 GAM18815.1 - 0.0029 17.4 5.0 0.19 11.5 2.7 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 GAM18815.1 - 0.012 15.8 0.0 0.078 13.2 0.0 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 GAM18815.1 - 0.035 13.3 0.1 0.041 13.0 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2254 PF10011.4 GAM18815.1 - 0.11 10.9 0.2 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Melittin PF01372.12 GAM18815.1 - 0.62 9.4 2.7 11 5.4 0.1 3.1 2 1 0 2 2 2 0 Melittin Abhydrolase_5 PF12695.2 GAM18816.1 - 1.4e-06 28.1 0.0 3.5e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM18816.1 - 3.7e-05 23.0 0.0 7.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAM18816.1 - 0.024 14.5 2.3 0.097 12.5 1.6 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1084 PF06454.6 GAM18817.1 - 9.1e-10 38.0 22.5 2.1e-09 36.8 15.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Nol1_Nop2_Fmu PF01189.12 GAM18818.1 - 3.2e-54 184.2 0.3 4e-31 108.4 0.0 2.8 1 1 1 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 GAM18818.1 - 0.0037 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM18818.1 - 0.046 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Dicty_REP PF05086.7 GAM18818.1 - 0.61 7.7 9.0 0.083 10.6 0.3 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein eIF-5_eIF-2B PF01873.12 GAM18819.1 - 4.8e-39 132.8 0.4 7.8e-39 132.1 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 GAM18819.1 - 0.023 14.0 0.4 0.057 12.7 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding PLRV_ORF5 PF01690.12 GAM18819.1 - 0.19 10.8 17.3 0.23 10.5 12.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mem_trans PF03547.13 GAM18819.1 - 0.46 8.7 3.4 0.63 8.2 2.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 GAM18819.1 - 0.98 7.0 18.9 1.2 6.7 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 GAM18819.1 - 2.7 7.7 25.8 3.5 7.3 17.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Arc_trans_TRASH PF08394.5 GAM18819.1 - 4.4 7.5 6.5 1.9 8.6 0.3 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain MIP-T3 PF10243.4 GAM18819.1 - 8 4.8 40.0 12 4.2 27.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 GAM18819.1 - 8.3 6.6 11.4 13 6.1 7.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ebola_NP PF05505.7 GAM18819.1 - 8.6 4.2 15.7 11 3.9 10.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Abhydrolase_5 PF12695.2 GAM18820.1 - 4.9e-25 87.9 0.0 7e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM18820.1 - 7.5e-17 61.9 0.0 1.7e-15 57.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM18820.1 - 1.3e-11 44.4 0.0 3.3e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM18820.1 - 2.1e-08 33.6 0.0 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAM18820.1 - 3.6e-08 33.1 0.1 0.0086 15.5 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF818 PF05677.7 GAM18820.1 - 1.1e-06 27.6 0.0 1.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 GAM18820.1 - 7.1e-05 22.5 0.0 0.00068 19.4 0.0 2.4 3 0 0 3 3 3 1 Putative lysophospholipase AXE1 PF05448.7 GAM18820.1 - 0.00011 20.8 0.0 0.053 12.0 0.0 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 GAM18820.1 - 0.0003 20.4 0.0 0.00068 19.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAM18820.1 - 0.0013 18.2 0.0 1 8.7 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 GAM18820.1 - 0.0014 17.9 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 GAM18820.1 - 0.0022 17.7 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 GAM18820.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S28 PF05577.7 GAM18820.1 - 0.017 13.7 0.0 0.032 12.8 0.0 1.4 1 1 0 1 1 1 0 Serine carboxypeptidase S28 DUF1749 PF08538.5 GAM18820.1 - 0.02 13.7 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF2305 PF10230.4 GAM18820.1 - 0.023 14.0 0.0 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 GAM18820.1 - 0.047 13.2 0.0 0.099 12.2 0.0 2.0 1 1 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 GAM18820.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.7 GAM18820.1 - 0.058 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 GAM18820.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1426 PF07234.6 GAM18820.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) TPR_11 PF13414.1 GAM18821.1 - 1.3e-19 69.5 1.8 1.2e-08 34.4 0.0 5.0 2 2 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 GAM18821.1 - 3.9e-16 57.5 0.8 0.0022 17.7 0.0 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM18821.1 - 1.7e-12 46.4 6.8 0.0062 16.1 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM18821.1 - 8.3e-12 44.8 8.2 0.00039 20.3 0.1 5.3 4 3 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18821.1 - 1.8e-10 39.7 2.9 0.037 13.8 0.0 5.1 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM18821.1 - 3.7e-09 36.0 2.2 0.69 10.2 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM18821.1 - 1.1e-08 35.3 0.5 0.00042 20.5 0.0 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM18821.1 - 2.5e-08 33.8 0.1 0.066 13.8 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM18821.1 - 0.00029 20.3 1.8 4 7.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.13 GAM18821.1 - 0.00036 20.3 1.9 1.7 8.5 0.8 4.2 3 2 0 3 3 3 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 GAM18821.1 - 0.00037 20.5 2.6 0.54 10.4 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 BAF1_ABF1 PF04684.8 GAM18821.1 - 0.00076 18.4 1.6 0.00099 18.0 1.1 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor TPR_6 PF13174.1 GAM18821.1 - 0.0018 18.5 3.2 0.91 10.1 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM18821.1 - 0.012 15.4 0.0 1.6 8.6 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_Ag35 PF03286.9 GAM18821.1 - 2.2 7.7 18.8 0.22 11.0 2.9 2.6 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DUF1764 PF08576.5 GAM18821.1 - 3.4 8.5 12.8 1.2 9.9 3.2 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF3295 PF11702.3 GAM18821.1 - 3.4 6.5 12.8 0.17 10.8 4.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Pkinase_Tyr PF07714.12 GAM18822.1 - 2.7e-56 190.4 0.0 3.7e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM18822.1 - 1.3e-54 185.0 0.0 1.9e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 GAM18822.1 - 3.2e-05 23.0 0.1 4.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM18822.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GDI PF00996.13 GAM18823.1 - 6.4e-207 687.1 1.8 7.5e-207 686.8 1.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 GAM18823.1 - 0.04 12.9 0.0 0.055 12.5 0.0 1.3 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Citrate_synt PF00285.16 GAM18824.1 - 4.3e-128 427.0 0.0 7.3e-128 426.2 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase LIM PF00412.17 GAM18825.1 - 4.5e-19 68.2 22.9 2.8e-11 43.3 4.0 3.0 3 0 0 3 3 3 2 LIM domain PH PF00169.24 GAM18825.1 - 2.5e-08 34.0 0.4 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 GAM18826.1 - 2.7e-06 27.6 0.6 0.00067 19.9 0.1 4.3 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM18826.1 - 0.00048 20.1 2.9 4.4 7.8 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 GAM18826.1 - 0.012 15.8 0.1 2.8 8.3 0.0 3.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Prefoldin_2 PF01920.15 GAM18827.1 - 4.7e-22 77.7 0.3 5.5e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 GAM18827.1 - 0.0059 16.2 1.1 0.41 10.3 0.7 2.1 1 1 0 1 1 1 1 Prefoldin subunit CASP_C PF08172.7 GAM18827.1 - 0.011 14.8 0.4 0.017 14.1 0.3 1.3 1 1 0 1 1 1 0 CASP C terminal Nsp1_C PF05064.8 GAM18827.1 - 0.027 14.0 2.8 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF1907 PF08925.6 GAM18827.1 - 0.053 12.6 0.2 0.065 12.3 0.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) BLOC1_2 PF10046.4 GAM18827.1 - 0.087 12.9 4.7 0.29 11.2 1.3 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.17 GAM18827.1 - 0.15 12.0 4.6 4.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArsR PF09824.4 GAM18827.1 - 0.15 11.3 0.9 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 ArsR transcriptional regulator TBPIP PF07106.8 GAM18827.1 - 0.16 11.4 2.7 0.73 9.3 0.5 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DEAD PF00270.24 GAM18828.1 - 8.7e-17 61.1 0.0 1.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM18828.1 - 2.8e-13 49.5 0.0 9.8e-13 47.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 GAM18828.1 - 0.0011 19.5 0.2 0.014 15.9 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1998) CLPTM1 PF05602.7 GAM18829.1 - 0.013 14.2 9.4 0.017 13.8 6.5 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DDRGK PF09756.4 GAM18829.1 - 0.093 12.1 20.4 0.13 11.6 14.2 1.1 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.4 GAM18829.1 - 0.094 10.9 35.6 0.1 10.8 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.4 GAM18829.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.4 1 1 1 2 2 1 0 Gti1/Pac2 family Erythro_esteras PF05139.9 GAM18829.1 - 0.29 10.2 14.1 0.39 9.8 9.7 1.1 1 0 0 1 1 1 0 Erythromycin esterase VID27 PF08553.5 GAM18829.1 - 0.45 8.6 11.8 0.55 8.3 8.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ycf1 PF05758.7 GAM18829.1 - 0.47 8.1 19.1 0.59 7.7 13.2 1.0 1 0 0 1 1 1 0 Ycf1 FUSC PF04632.7 GAM18829.1 - 0.52 8.6 7.3 0.59 8.5 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hid1 PF12722.2 GAM18829.1 - 0.56 7.8 11.8 0.62 7.6 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HlyD_2 PF12700.2 GAM18829.1 - 0.66 9.0 15.4 0.79 8.8 10.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Neur_chan_memb PF02932.11 GAM18829.1 - 0.74 9.6 8.2 0.97 9.2 5.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vitellogenin_N PF01347.17 GAM18829.1 - 0.9 7.6 21.9 1.1 7.4 15.2 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region FAM60A PF15396.1 GAM18829.1 - 0.95 9.1 10.1 1.2 8.8 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RNA_pol_Rpb1_5 PF04998.12 GAM18829.1 - 1.1 8.3 9.0 1.4 8.1 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SprA-related PF12118.3 GAM18829.1 - 1.2 8.3 33.0 1.8 7.8 22.9 1.4 1 0 0 1 1 1 0 SprA-related family Exonuc_VII_L PF02601.10 GAM18829.1 - 1.6 7.8 16.5 1.9 7.6 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.11 GAM18829.1 - 1.6 7.2 4.0 1.6 7.2 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3492 PF11997.3 GAM18829.1 - 1.8 8.0 9.1 2.3 7.6 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CobN-Mg_chel PF02514.11 GAM18829.1 - 3 5.1 12.9 3.6 4.8 8.9 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Hom_end_hint PF05203.11 GAM18829.1 - 3.2 7.4 9.3 4.2 7.0 6.5 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Med15 PF09606.5 GAM18829.1 - 3.3 5.7 53.9 3.9 5.5 37.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S49_N PF08496.5 GAM18829.1 - 3.4 7.4 13.3 5.6 6.7 9.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MMPL PF03176.10 GAM18829.1 - 4.1 6.0 6.7 5.9 5.4 4.6 1.2 1 0 0 1 1 1 0 MMPL family TFIIA PF03153.8 GAM18829.1 - 4.1 7.2 26.5 5 6.9 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipoprotein_X PF03305.8 GAM18829.1 - 4.4 6.6 12.1 6.5 6.0 8.4 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein FNIP_N PF14636.1 GAM18829.1 - 5.2 7.5 13.5 9 6.7 9.4 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF4045 PF13254.1 GAM18829.1 - 5.5 6.1 13.2 6.9 5.8 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) V_ATPase_I PF01496.14 GAM18829.1 - 6 4.5 13.1 7.7 4.2 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 GAM18829.1 - 7.5 5.4 25.1 11 4.9 17.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Glyco_transf_15 PF01793.11 GAM18829.1 - 8.3 5.2 13.2 11 4.8 9.2 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4220 PF13968.1 GAM18829.1 - 9.6 5.1 9.6 12 4.8 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Acetyltransf_4 PF13420.1 GAM18831.1 - 2.8e-21 76.1 2.2 7e-14 52.0 0.1 2.0 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM18831.1 - 1e-07 32.2 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM18831.1 - 3e-07 30.3 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM18831.1 - 0.00097 19.2 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM18831.1 - 0.0044 16.7 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAM18831.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM18831.1 - 0.03 14.4 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Beta_helix PF13229.1 GAM18832.1 - 4.8e-07 29.6 19.5 5e-05 23.0 9.0 3.2 1 1 1 2 2 2 2 Right handed beta helix region EamA PF00892.15 GAM18833.1 - 1.9e-40 137.7 29.9 2e-22 79.5 6.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 GAM18833.1 - 7.2e-10 39.0 24.8 1e-05 25.7 6.0 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 GAM18833.1 - 3.6e-05 23.4 18.4 0.00033 20.3 2.7 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.9 GAM18833.1 - 0.0017 17.3 0.9 0.032 13.1 0.1 2.5 2 0 0 2 2 2 1 Magnesium transporter NIPA DUF1632 PF07857.7 GAM18833.1 - 0.0097 15.1 0.3 0.79 8.9 0.0 2.5 2 0 0 2 2 2 1 CEO family (DUF1632) DUF1614 PF07758.6 GAM18833.1 - 0.015 15.0 6.9 0.1 12.3 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) Nucleoplasmin PF03066.10 GAM18833.1 - 0.25 10.8 6.4 0.53 9.7 4.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF606 PF04657.8 GAM18833.1 - 1.6 8.7 14.0 5.9 6.9 3.7 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF606 PBP1_TM PF14812.1 GAM18833.1 - 1.7 9.0 11.7 0.52 10.6 4.7 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 GAM18833.1 - 7.1 6.8 9.5 1.9 8.6 4.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BK_channel_a PF03493.13 GAM18834.1 - 1.8e-24 85.5 0.4 2.6e-23 81.8 0.0 3.0 3 0 0 3 3 3 1 Calcium-activated BK potassium channel alpha subunit Trypan_PARP PF05887.6 GAM18835.1 - 4.5 7.0 9.0 0.51 10.1 1.3 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FG-GAP_2 PF14312.1 GAM18836.1 - 0.0013 18.6 1.5 0.19 11.7 0.1 3.6 3 0 0 3 3 3 1 FG-GAP repeat GCC2_GCC3 PF07699.8 GAM18836.1 - 0.02 14.4 7.7 0.14 11.7 5.3 2.5 1 1 0 1 1 1 0 GCC2 and GCC3 Cnd1_N PF12922.2 GAM18837.1 - 0.013 15.1 1.9 0.027 14.1 0.3 2.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term RAP1 PF07218.6 GAM18837.1 - 9 4.2 29.1 1.8 6.5 0.9 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Beta_helix PF13229.1 GAM18838.1 - 1.3e-09 38.0 64.8 0.0092 15.7 13.5 4.4 1 1 1 2 2 2 1 Right handed beta helix region Ank_2 PF12796.2 GAM18840.1 - 1.3e-44 150.3 6.5 1.4e-09 38.1 0.1 6.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM18840.1 - 7.7e-39 131.4 7.3 2.5e-05 24.6 0.0 10.2 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM18840.1 - 4.6e-37 125.2 10.0 0.00061 19.9 0.0 13.9 2 2 12 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18840.1 - 7.7e-28 93.7 10.5 0.43 10.9 0.0 14.3 11 5 5 16 16 16 8 Ankyrin repeat Ank PF00023.25 GAM18840.1 - 3.9e-25 86.3 6.9 0.084 12.7 0.0 14.4 13 2 2 15 15 15 5 Ankyrin repeat Rbsn PF11464.3 GAM18840.1 - 0.018 14.6 7.4 49 3.6 0.0 6.8 10 0 0 10 10 10 0 Rabenosyn Rab binding domain RNase_P_p30 PF01876.11 GAM18840.1 - 0.02 14.1 0.0 20 4.3 0.0 4.7 5 0 0 5 5 5 0 RNase P subunit p30 FBD PF08387.5 GAM18840.1 - 0.085 12.3 0.0 34 3.9 0.0 4.7 5 1 0 5 5 5 0 FBD DUF2462 PF09495.5 GAM18840.1 - 0.12 13.1 0.7 2.6e+02 2.4 0.0 5.6 7 2 1 8 8 8 0 Protein of unknown function (DUF2462) Kunitz_BPTI PF00014.18 GAM18840.1 - 0.27 11.4 2.1 16 5.8 0.0 4.3 4 1 2 6 6 6 0 Kunitz/Bovine pancreatic trypsin inhibitor domain SNF5 PF04855.7 GAM18841.1 - 1.4e-36 126.2 2.8 1.4e-36 126.2 1.9 3.2 2 2 0 2 2 2 1 SNF5 / SMARCB1 / INI1 DUF3439 PF11921.3 GAM18841.1 - 1.3 8.7 4.8 2.9 7.6 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM18841.1 - 7.8 6.2 14.7 1.9 8.2 5.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Ras PF00071.17 GAM18842.1 - 0.00029 20.2 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 Ras family PAS PF00989.19 GAM18842.1 - 1.2 8.9 5.8 0.6 9.9 0.4 2.4 2 0 0 2 2 2 0 PAS fold UreE_C PF05194.7 GAM18842.1 - 1.2 9.2 24.1 0.2 11.7 5.2 3.5 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain Ras PF00071.17 GAM18843.1 - 1e-07 31.4 0.0 1.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM18843.1 - 0.00022 21.7 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM18843.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.1 GAM18843.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 GAM18843.1 - 0.02 14.5 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAM18843.1 - 0.023 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAM18843.1 - 0.043 13.7 0.1 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Alpha_GJ PF03229.8 GAM18843.1 - 0.61 10.4 8.3 0.38 11.1 0.3 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Pex14_N PF04695.8 GAM18843.1 - 3.1 7.8 12.4 1.8 8.6 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GRAM PF02893.15 GAM18844.1 - 5.3e-12 45.0 0.4 2e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 GRAM domain RNB PF00773.14 GAM18845.1 - 2.5e-55 188.0 6.6 5.6e-55 186.8 4.6 1.6 1 0 0 1 1 1 1 RNB domain Curlin_rpt PF07012.7 GAM18846.1 - 0.04 13.6 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Curlin associated repeat Mtc PF03820.12 GAM18850.1 - 3e-101 338.1 0.5 3.4e-101 337.9 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PLU-1 PF08429.6 GAM18851.1 - 0.018 13.9 0.4 0.055 12.3 0.0 2.0 2 0 0 2 2 2 0 PLU-1-like protein WD40 PF00400.27 GAM18852.1 - 9.3e-11 41.1 7.1 0.028 14.3 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Exonuc_VII_L PF02601.10 GAM18852.1 - 0.39 9.8 7.7 0.58 9.3 5.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3371 PF11851.3 GAM18852.1 - 0.72 10.5 11.4 0.76 10.4 6.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Sulfatase_C PF14707.1 GAM18852.1 - 1.1 9.5 7.9 2 8.7 5.5 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase IncA PF04156.9 GAM18852.1 - 1.9 8.0 14.8 3 7.4 10.3 1.2 1 0 0 1 1 1 0 IncA protein DUF4557 PF15101.1 GAM18852.1 - 3.9 7.2 9.7 6.8 6.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 GAM18852.1 - 4.3 5.4 20.2 5.4 5.1 14.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OmpH PF03938.9 GAM18852.1 - 6.2 6.7 18.9 14 5.6 13.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lipase_3 PF01764.20 GAM18853.1 - 2.2e-10 40.2 0.0 4.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM18853.1 - 0.0082 15.5 0.2 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAM18853.1 - 0.037 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GST_C PF00043.20 GAM18854.1 - 1.5e-11 44.1 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM18854.1 - 1.5e-07 31.4 0.0 3.3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM18854.1 - 6.4e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM18854.1 - 9.8e-07 28.5 0.1 1.9e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM18854.1 - 2.2e-06 27.7 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM18854.1 - 4.3e-05 23.9 0.0 7.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LRR_4 PF12799.2 GAM18855.1 - 2.1e-18 65.5 14.5 1.7e-07 30.7 0.0 6.3 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18855.1 - 5.4e-12 45.2 13.0 3.9e-06 26.5 1.1 3.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 GAM18855.1 - 6.4e-06 25.4 6.0 2.6 8.4 0.0 6.6 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 GAM18855.1 - 0.00025 20.6 0.8 0.0027 17.3 0.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 GAM18855.1 - 0.0069 16.3 10.8 3.3 8.0 0.0 5.9 6 1 1 7 7 7 2 Leucine Rich repeat DUF1451 PF07295.6 GAM18855.1 - 0.16 11.7 10.0 1.2 8.9 2.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1451) LRR_7 PF13504.1 GAM18855.1 - 1.9 9.0 8.4 1e+02 3.8 0.0 6.2 7 1 0 7 7 7 0 Leucine rich repeat EF-hand_8 PF13833.1 GAM18856.1 - 6.6e-12 44.8 0.1 4e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 GAM18856.1 - 1.1e-10 41.4 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM18856.1 - 5.8e-10 37.7 0.1 0.00033 19.7 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAM18856.1 - 5e-06 25.9 0.0 0.0078 16.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM18856.1 - 0.0024 17.1 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.2 GAM18856.1 - 0.14 11.8 0.1 7 6.4 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand LEA_2 PF03168.8 GAM18857.1 - 0.00052 20.3 0.5 0.61 10.4 0.0 5.1 5 0 0 5 5 5 1 Late embryogenesis abundant protein Nop53 PF07767.6 GAM18858.1 - 0.016 14.2 5.4 0.018 14.0 3.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Vfa1 PF08432.5 GAM18858.1 - 0.24 11.3 4.7 0.26 11.2 3.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4611 PF15387.1 GAM18858.1 - 0.46 10.6 6.0 0.63 10.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pox_RNA_Pol_19 PF05320.7 GAM18858.1 - 1.6 8.4 4.6 1.9 8.2 3.2 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Prothymosin PF03247.9 GAM18858.1 - 2.8 8.1 12.7 3.6 7.7 8.8 1.4 1 1 0 1 1 1 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 GAM18858.1 - 3.2 7.2 8.4 3.8 7.0 5.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 GAM18858.1 - 4.7 6.3 7.1 4.7 6.3 4.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.8 GAM18858.1 - 6.6 4.3 7.2 6.9 4.3 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 GAM18858.1 - 6.8 4.5 7.0 7 4.5 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAM18858.1 - 7.6 4.3 10.1 8 4.2 7.0 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 GAM18858.1 - 8.2 5.4 10.2 8.6 5.3 7.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ank_3 PF13606.1 GAM18859.1 - 0.037 14.2 0.9 1.7e+02 2.9 0.0 5.5 7 0 0 7 7 7 0 Ankyrin repeat DUF1084 PF06454.6 GAM18860.1 - 5e-08 32.3 25.6 1.1e-07 31.1 17.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Clat_adaptor_s PF01217.15 GAM18861.1 - 5.6e-09 35.8 1.7 6.8e-09 35.5 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RICTOR_M PF14666.1 GAM18861.1 - 0.0069 15.4 0.1 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, middle domain CBM49 PF09478.5 GAM18862.1 - 8.4e-14 51.4 0.1 1.4e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 DUF605 PF04652.11 GAM18862.1 - 1.6 8.0 31.6 2.2 7.5 21.9 1.2 1 0 0 1 1 1 0 Vta1 like Melibiase PF02065.13 GAM18863.1 - 4.1e-25 88.3 0.7 7.2e-20 71.0 0.0 2.3 1 1 0 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 GAM18863.1 - 7.9e-05 21.8 0.1 0.00012 21.3 0.1 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 TrbC PF04956.8 GAM18863.1 - 0.059 13.3 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 TrbC/VIRB2 family MobB PF03205.9 GAM18864.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ToxN_toxin PF13958.1 GAM18865.1 - 0.039 13.6 0.5 0.049 13.3 0.3 1.2 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DUF2435 PF10363.4 GAM18866.1 - 1.8e-07 30.9 0.0 9.7e-06 25.4 0.0 3.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 GAM18866.1 - 2.4e-05 23.7 0.1 6.7e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF3385 PF11865.3 GAM18866.1 - 0.0079 16.1 5.9 5.4 6.9 0.1 4.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) BPL_LplA_LipB PF03099.14 GAM18867.1 - 2.3e-15 56.7 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Co_AT_N PF12557.3 GAM18867.1 - 0.6 10.0 2.1 1.1 9.2 1.5 1.4 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Radical_SAM PF04055.16 GAM18868.1 - 2.4e-10 40.8 0.2 5.2e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 Radical SAM superfamily 7tm_3 PF00003.17 GAM18869.1 - 7.6e-23 81.0 32.2 7.6e-23 81.0 22.3 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR PIRT PF15099.1 GAM18869.1 - 0.47 9.6 5.7 0.83 8.8 3.1 2.1 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family CH PF00307.26 GAM18870.1 - 3.8e-34 116.9 15.9 3.6e-12 46.2 0.1 5.7 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM18870.1 - 0.00011 21.7 7.0 0.073 12.7 0.0 4.0 3 1 1 4 4 4 2 CAMSAP CH domain TMF_DNA_bd PF12329.3 GAM18870.1 - 0.0027 17.4 6.2 0.0027 17.4 4.3 14.6 7 5 6 14 14 14 5 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 GAM18870.1 - 0.0078 15.4 62.9 0.0051 16.0 5.0 6.4 3 1 2 6 6 6 6 Reovirus sigma C capsid protein zf-C3HC4_3 PF13920.1 GAM18871.1 - 6.5e-08 32.1 5.3 1.1e-07 31.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM18871.1 - 1.1e-07 31.7 10.2 2.2e-07 30.7 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM18871.1 - 1.2e-06 28.0 8.3 2.5e-06 27.0 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM18871.1 - 3.9e-06 26.5 8.7 7.9e-06 25.5 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM18871.1 - 1.1e-05 25.0 7.9 2.2e-05 24.0 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 GAM18871.1 - 0.00063 19.2 4.5 0.00063 19.2 3.1 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 GAM18871.1 - 0.24 11.3 11.9 2.1 8.2 7.8 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAM18871.1 - 0.3 10.8 5.1 0.9 9.3 3.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 GAM18871.1 - 0.39 10.8 4.4 0.95 9.6 3.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 GAM18871.1 - 0.41 10.2 7.4 1.2 8.7 5.1 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 GAM18871.1 - 0.83 9.4 5.3 2.9 7.6 3.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 GAM18871.1 - 4.5 6.9 7.2 13 5.4 1.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NAAA-beta PF15508.1 GAM18872.1 - 9.9e-16 57.8 0.0 1.6e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CBAH PF02275.13 GAM18872.1 - 1.3e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family DUF2824 PF11039.3 GAM18872.1 - 0.048 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2824) Pectate_lyase_3 PF12708.2 GAM18873.1 - 0.51 10.4 9.1 0.91 9.5 6.3 1.4 1 0 0 1 1 1 0 Pectate lyase superfamily protein Beta_helix PF13229.1 GAM18874.1 - 1.1e-05 25.2 29.3 0.0006 19.5 11.3 2.8 1 1 1 2 2 2 2 Right handed beta helix region Endotoxin_N PF03945.9 GAM18875.1 - 2.2e-06 27.2 2.0 5.2e-06 26.0 1.4 1.6 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain CDtoxinA PF03498.9 GAM18875.1 - 0.0022 17.3 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 Cytolethal distending toxin A/C family Metal_resist PF13801.1 GAM18877.1 - 0.074 13.0 0.3 0.089 12.7 0.2 1.0 1 0 0 1 1 1 0 Heavy-metal resistance Tcell_CD4_Cterm PF12104.3 GAM18877.1 - 0.17 11.4 0.8 0.3 10.7 0.5 1.4 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region Dicty_REP PF05086.7 GAM18878.1 - 0.53 7.9 3.5 0.56 7.9 2.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_C48 PF02902.14 GAM18879.1 - 3e-08 33.5 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DKCLD PF08068.7 GAM18879.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 DKCLD (NUC011) domain DUF3579 PF12112.3 GAM18879.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) DUF3644 PF12358.3 GAM18880.1 - 0.091 13.0 0.3 0.26 11.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) AAA_16 PF13191.1 GAM18881.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 GAM18882.1 - 0.11 12.6 0.1 0.64 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain HTH_Tnp_Tc5 PF03221.11 GAM18884.1 - 1.7e-05 24.5 0.2 5.8e-05 22.8 0.1 1.8 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Transglut_core2 PF13369.1 GAM18884.1 - 0.035 13.5 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF3647 PF12363.3 GAM18884.1 - 0.078 13.0 0.1 0.43 10.6 0.0 2.0 1 1 1 2 2 2 0 Phage protein E1_DerP2_DerF2 PF02221.10 GAM18885.1 - 5.6e-17 62.2 0.0 6.5e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 ML domain FHA PF00498.21 GAM18886.1 - 9.3e-17 60.9 0.0 2.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain LBP_BPI_CETP PF01273.20 GAM18886.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain DUF4430 PF14478.1 GAM18886.1 - 0.14 12.1 0.5 0.49 10.4 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) AUX_IAA PF02309.11 GAM18886.1 - 0.32 10.6 8.3 0.39 10.4 4.7 1.7 1 1 1 2 2 2 0 AUX/IAA family SpoIIIAH PF12685.2 GAM18886.1 - 8 5.9 16.2 7.2 6.0 10.3 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF3677 PF12432.3 GAM18887.1 - 4.9e-11 42.9 0.0 5e-08 33.2 0.0 3.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3677) Pribosyltran_N PF13793.1 GAM18888.1 - 6.4e-47 158.0 1.0 1.5e-45 153.6 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM18888.1 - 9.1e-42 142.8 7.1 1.8e-38 132.1 1.3 3.5 3 1 1 4 4 4 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM18888.1 - 1.5e-12 47.3 1.5 3.9e-12 45.9 1.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM18888.1 - 0.0024 17.0 0.2 0.0043 16.2 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CAF1 PF04857.15 GAM18889.1 - 1.5e-67 227.6 0.0 3.2e-67 226.6 0.0 1.5 1 0 0 1 1 1 1 CAF1 family ribonuclease PLDc_2 PF13091.1 GAM18891.1 - 5.6e-22 77.8 0.3 1.6e-16 60.1 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM18891.1 - 1.3e-07 31.1 2.2 0.00045 19.9 0.1 3.4 3 0 0 3 3 3 2 Phospholipase D Active site motif COX6B PF02297.12 GAM18892.1 - 1.1e-18 66.9 2.5 1.3e-18 66.7 1.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 GAM18892.1 - 0.002 17.9 1.0 0.0034 17.2 0.7 1.5 1 0 0 1 1 1 1 CHCH domain Guanylate_cyc_2 PF09778.4 GAM18893.1 - 2.1e-44 151.2 0.1 1.9e-42 144.8 0.1 2.1 1 1 0 1 1 1 1 Guanylylate cyclase Peptidase_C39_2 PF13529.1 GAM18893.1 - 5.4e-08 33.3 0.5 8.9e-06 26.1 0.3 2.4 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.10 GAM18893.1 - 5.1e-07 29.5 0.1 0.0027 17.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase C39 family Transpep_BrtH PF14399.1 GAM18893.1 - 1.7e-06 27.5 0.3 1.6e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 NlpC/p60-like transpeptidase HECT PF00632.20 GAM18894.1 - 3e-80 269.7 0.0 4.4e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Kelch_4 PF13418.1 GAM18894.1 - 7.3e-26 89.6 12.4 1.7e-08 34.0 0.2 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM18894.1 - 1.3e-22 79.2 7.8 8.3e-07 28.8 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 GAM18894.1 - 2.6e-22 78.3 14.2 4.8e-06 26.5 0.1 5.8 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM18894.1 - 1.9e-21 75.2 8.9 4.2e-07 29.8 0.2 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 GAM18894.1 - 4.7e-20 70.8 4.0 1.1e-07 31.2 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 GAM18894.1 - 5.7e-15 54.4 9.7 5.2e-06 26.0 0.2 4.8 4 1 0 4 4 4 3 Kelch motif cwf18 PF08315.7 GAM18895.1 - 4.3e-20 72.4 13.1 4.3e-20 72.4 9.1 3.5 2 2 0 2 2 2 1 cwf18 pre-mRNA splicing factor Menin PF05053.8 GAM18895.1 - 0.67 8.0 23.4 0.069 11.3 4.4 2.2 2 0 0 2 2 2 0 Menin LRR_6 PF13516.1 GAM18896.1 - 4.4e-36 118.8 51.6 6.9e-05 22.5 0.2 15.6 14 1 2 16 16 16 10 Leucine Rich repeat LRR_4 PF12799.2 GAM18896.1 - 1.1e-14 53.5 45.7 0.0026 17.3 0.2 10.0 7 4 2 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM18896.1 - 1.1e-11 43.0 27.6 0.56 10.4 0.1 13.0 16 1 0 16 16 16 4 Leucine Rich Repeat LRR_8 PF13855.1 GAM18896.1 - 6.9e-07 28.9 44.9 0.0047 16.6 1.3 9.6 7 3 1 9 9 9 6 Leucine rich repeat F-box-like PF12937.2 GAM18896.1 - 0.00098 18.8 0.5 0.00098 18.8 0.4 2.1 3 0 0 3 3 3 1 F-box-like LRR_7 PF13504.1 GAM18896.1 - 0.0089 16.0 39.1 9 6.9 0.0 12.4 14 0 0 14 14 14 1 Leucine rich repeat Annexin PF00191.15 GAM18896.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Annexin Pkinase PF00069.20 GAM18897.1 - 3.8e-77 258.9 0.0 5e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18897.1 - 4.3e-42 143.9 0.0 5.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM18897.1 - 6.8e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM18897.1 - 0.00046 19.2 0.0 0.0015 17.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 GAM18897.1 - 0.0068 15.7 0.1 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAM18897.1 - 0.18 11.4 0.0 1.1 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ten1_2 PF15490.1 GAM18898.1 - 4.5e-13 48.8 0.2 2.1e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 Telomere-capping, CST complex subunit Tir_receptor_C PF07489.6 GAM18898.1 - 0.47 10.1 3.3 0.26 11.0 1.1 1.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Peptidase_M18 PF02127.10 GAM18899.1 - 2e-155 517.5 0.0 2.2e-155 517.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 GAM18899.1 - 1.7e-07 30.2 0.1 3e-06 26.2 0.0 2.4 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase HSP90 PF00183.13 GAM18900.1 - 2.9e-71 240.4 1.9 1.7e-68 231.3 0.3 2.3 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 GAM18900.1 - 8e-12 44.9 0.1 1.9e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM18900.1 - 5.2e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDO_I PF05995.7 GAM18901.1 - 0.094 11.8 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I Saccharop_dh PF03435.13 GAM18902.1 - 1.1e-75 254.9 0.0 2.8e-75 253.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM18902.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FNIP PF05725.7 GAM18903.1 - 4.8e-48 160.8 14.3 3.4e-11 42.8 0.1 6.7 5 1 0 6 6 6 6 FNIP Repeat DUF1769 PF08588.5 GAM18903.1 - 0.016 15.1 4.3 7.8 6.5 0.0 4.8 5 1 1 6 6 6 0 Protein of unknown function (DUF1769) Peptidase_S8 PF00082.17 GAM18904.1 - 5.4e-42 143.8 0.0 7.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF843 PF05814.6 GAM18904.1 - 0.06 13.1 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Usg PF06233.7 GAM18905.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Usg-like family RGS PF00615.14 GAM18906.1 - 4.9e-24 84.7 2.9 4.9e-24 84.7 2.0 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain LRR_4 PF12799.2 GAM18906.1 - 3.1e-20 71.3 16.7 1.2e-07 31.2 0.5 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM18906.1 - 8.4e-16 57.4 11.1 1.2e-11 44.1 1.6 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 GAM18906.1 - 6.8e-12 43.6 5.6 0.13 12.3 0.1 5.5 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 GAM18906.1 - 2e-07 30.0 1.3 4.7 7.8 0.0 5.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 GAM18906.1 - 0.0003 20.5 5.2 0.19 11.8 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich repeat LRR_5 PF13306.1 GAM18906.1 - 0.014 15.0 1.2 0.072 12.7 0.1 2.4 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) TraB PF01963.12 GAM18907.1 - 7.6e-27 94.3 3.9 9.5e-25 87.5 0.0 2.6 3 0 0 3 3 3 2 TraB family Glyco_transf_10 PF00852.14 GAM18908.1 - 9.8e-46 155.9 1.2 2e-45 154.8 0.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Pkinase_Tyr PF07714.12 GAM18909.1 - 1.7e-54 184.6 0.0 2.7e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM18909.1 - 1.6e-52 178.2 0.0 3.3e-52 177.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAM18909.1 - 1.6e-32 111.7 3.5 1.9e-12 47.3 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM18909.1 - 1.8e-26 91.5 3.5 3.1e-08 33.6 0.1 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM18909.1 - 1.9e-26 90.5 5.8 5.2e-06 26.0 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 GAM18909.1 - 3.7e-26 90.9 3.7 0.00011 22.5 0.0 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18909.1 - 4.6e-22 75.9 3.2 2.4e-05 24.1 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat SAM_1 PF00536.25 GAM18909.1 - 1.2e-14 54.1 0.3 4e-14 52.5 0.2 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM18909.1 - 4.7e-10 39.1 0.2 1.5e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.18 GAM18909.1 - 0.014 15.0 0.1 0.087 12.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family MSC PF09402.5 GAM18911.1 - 3.1e-36 124.7 0.0 6.1e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain LMBR1 PF04791.11 GAM18911.1 - 0.19 10.2 0.0 0.19 10.2 0.0 2.0 2 1 0 2 2 2 0 LMBR1-like membrane protein Rpr2 PF04032.11 GAM18912.1 - 3.2e-19 68.5 7.2 3.2e-19 68.5 5.0 2.0 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cytidylate_kin2 PF13189.1 GAM18912.1 - 0.044 13.6 3.3 0.061 13.2 1.9 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family FUR PF01475.14 GAM18912.1 - 0.18 11.6 5.7 0.13 12.1 1.0 2.4 1 1 2 3 3 3 0 Ferric uptake regulator family DUF3450 PF11932.3 GAM18912.1 - 4.3 6.5 10.7 4.2 6.5 4.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GAF_2 PF13185.1 GAM18913.1 - 0.0018 18.7 0.0 0.0028 18.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain Kelch_6 PF13964.1 GAM18914.1 - 1e-16 60.3 7.6 1.6e-05 24.8 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM18914.1 - 9.2e-15 54.1 5.1 1.1e-05 25.1 0.2 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM18914.1 - 2.9e-07 30.4 12.4 5.9e-05 23.1 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain zf-B_box PF00643.19 GAM18914.1 - 3.6e-07 29.9 4.1 1.2e-06 28.3 2.8 1.9 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.20 GAM18914.1 - 1.5e-05 24.4 8.4 0.076 12.5 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAM18914.1 - 0.00022 20.8 2.7 4.8 7.1 0.0 4.8 4 0 0 4 4 4 2 Kelch motif FA_desaturase PF00487.19 GAM18915.1 - 1.7e-07 30.9 6.7 1.9e-05 24.2 0.0 2.7 3 0 0 3 3 3 2 Fatty acid desaturase YibE_F PF07907.6 GAM18915.1 - 0.055 12.6 4.0 0.13 11.4 0.6 2.0 1 1 1 2 2 2 0 YibE/F-like protein adh_short PF00106.20 GAM18916.1 - 1.5e-33 116.1 0.0 1.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM18916.1 - 7.4e-19 68.1 0.0 9.7e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM18916.1 - 2.5e-12 47.1 0.0 3.2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM18916.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM18916.1 - 1.4e-05 25.1 0.0 3.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM18916.1 - 1.5e-05 24.0 0.1 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 GAM18916.1 - 1.5e-05 25.1 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 GAM18916.1 - 7.4e-05 21.8 0.1 0.0001 21.4 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 GAM18916.1 - 7.5e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 GAM18916.1 - 0.00098 17.9 0.2 0.0016 17.1 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF258 PF03193.11 GAM18916.1 - 0.016 14.4 0.6 0.089 11.9 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 NAD_binding_7 PF13241.1 GAM18916.1 - 0.05 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Y_phosphatase PF00102.22 GAM18917.1 - 1.5e-80 269.9 1.9 2e-80 269.4 1.3 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM18917.1 - 1e-05 25.1 0.0 2.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAM18917.1 - 0.0045 17.2 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM18917.1 - 0.0056 16.7 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate FAM195 PF14799.1 GAM18917.1 - 0.016 15.0 0.9 0.041 13.7 0.2 2.1 2 0 0 2 2 2 0 FAM195 family OST3_OST6 PF04756.8 GAM18920.1 - 1.2e-12 47.6 7.2 2.6e-12 46.6 5.0 1.6 1 0 0 1 1 1 1 OST3 / OST6 family AtpR PF12966.2 GAM18920.1 - 0.17 12.0 8.0 0.43 10.7 2.1 2.5 2 0 0 2 2 2 0 N-ATPase, AtpR subunit DUF4131 PF13567.1 GAM18920.1 - 0.19 11.1 8.3 1.4 8.3 1.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) COX15-CtaA PF02628.10 GAM18920.1 - 0.33 9.7 7.8 1.3 7.8 0.1 2.6 3 0 0 3 3 3 0 Cytochrome oxidase assembly protein H_PPase PF03030.11 GAM18920.1 - 1.1 7.4 4.6 8.8 4.4 3.2 1.9 1 1 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF2254 PF10011.4 GAM18920.1 - 3.2 6.1 10.3 1.1 7.6 3.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF805 PF05656.9 GAM18920.1 - 7 6.5 8.7 6.9 6.5 4.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF805) AcetylCoA_hydro PF02550.10 GAM18921.1 - 8.7e-40 136.6 0.0 1.5e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 GAM18921.1 - 1e-35 122.7 0.0 1.6e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Ded_cyto PF06920.8 GAM18922.1 - 1.6e-50 170.8 4.5 2.7e-50 170.1 0.7 2.7 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM18922.1 - 1e-41 142.6 0.6 2.4e-41 141.3 0.4 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 GAM18922.1 - 8.7e-06 25.4 3.0 2.6e-05 23.9 0.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3398) RPAP1_N PF08621.5 GAM18922.1 - 0.0057 16.2 0.2 0.017 14.6 0.1 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal Enkurin PF13864.1 GAM18924.1 - 0.0078 16.4 1.7 0.014 15.6 1.2 1.3 1 0 0 1 1 1 1 Calmodulin-binding DUF573 PF04504.9 GAM18924.1 - 0.026 14.7 0.6 0.045 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF573 OmpA PF00691.15 GAM18924.1 - 0.032 14.6 1.4 0.059 13.7 0.7 1.6 1 1 0 1 1 1 0 OmpA family Spt5_N PF11942.3 GAM18924.1 - 0.073 13.6 2.6 0.12 12.9 1.8 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF912 PF06024.7 GAM18924.1 - 0.15 12.1 1.8 0.64 10.1 1.0 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DAO PF01266.19 GAM18925.1 - 1.6e-54 185.2 0.0 2.2e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM18925.1 - 0.00012 21.0 0.1 0.024 13.5 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Mqo PF06039.10 GAM18925.1 - 0.0022 16.2 0.2 0.33 9.0 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 GAM18925.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM18925.1 - 0.012 14.7 0.0 0.44 9.5 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 GAM18925.1 - 0.016 14.2 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 GAM18925.1 - 0.051 13.6 0.2 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM18925.1 - 0.072 13.5 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM18925.1 - 0.11 12.2 0.3 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM18925.1 - 0.12 12.4 0.0 8.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shisa PF13908.1 GAM18926.1 - 0.026 14.7 9.6 0.11 12.6 5.1 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator CCER1 PF15482.1 GAM18926.1 - 4.5 6.8 11.4 6 6.4 7.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 RasGEF_N PF00618.15 GAM18927.1 - 4.3e-05 23.5 1.0 0.00017 21.6 0.7 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif ERM PF00769.14 GAM18927.1 - 0.0062 16.0 4.4 0.11 11.9 0.1 2.4 2 0 0 2 2 2 2 Ezrin/radixin/moesin family RasGEF PF00617.14 GAM18928.1 - 3e-48 164.0 2.5 6.7e-48 162.9 1.7 1.5 1 0 0 1 1 1 1 RasGEF domain DUF416 PF04222.7 GAM18928.1 - 5.7 6.0 10.3 0.63 9.1 0.3 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF416) Pkinase PF00069.20 GAM18929.1 - 1.1e-59 201.7 0.0 1.6e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18929.1 - 7.5e-44 149.7 0.0 1.1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM18929.1 - 0.011 15.4 0.3 0.18 11.4 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM18929.1 - 0.063 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Syja_N PF02383.13 GAM18930.1 - 2.9e-86 289.1 0.0 5e-86 288.3 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain FNIP PF05725.7 GAM18931.1 - 8.8e-86 281.6 27.1 1.3e-13 50.6 0.1 11.3 8 1 5 13 13 13 12 FNIP Repeat Pkinase PF00069.20 GAM18932.1 - 1.8e-63 214.0 0.0 2.7e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18932.1 - 4.8e-44 150.3 0.0 7.1e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TIG PF01833.19 GAM18932.1 - 2.5e-18 65.8 23.3 1e-07 31.8 0.6 5.5 4 0 0 4 4 4 4 IPT/TIG domain Kdo PF06293.9 GAM18932.1 - 0.03 13.3 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM18932.1 - 0.075 11.9 0.0 0.3 10.0 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 GAM18932.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EGF_2 PF07974.8 GAM18932.1 - 1.3 9.2 4.9 2.6 8.2 3.4 1.5 1 0 0 1 1 1 0 EGF-like domain GFA PF04828.9 GAM18933.1 - 4.1e-05 23.4 1.8 4.1e-05 23.4 1.2 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 GAM18933.1 - 0.0018 17.7 1.5 0.0018 17.7 1.0 2.0 2 0 0 2 2 2 1 CSL zinc finger zf-C3HC4_2 PF13923.1 GAM18933.1 - 0.0027 17.6 0.2 0.0027 17.6 0.2 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM18933.1 - 0.0067 16.0 0.7 0.0067 16.0 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Cys_rich_CWC PF14375.1 GAM18933.1 - 0.046 13.6 1.9 0.046 13.6 1.3 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC zf-RING_5 PF14634.1 GAM18933.1 - 0.65 9.7 10.8 3.4 7.4 7.5 2.3 1 1 0 1 1 1 0 zinc-RING finger domain NosD PF05048.8 GAM18934.1 - 0.0039 16.3 6.2 0.0058 15.8 4.3 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.1 GAM18934.1 - 0.023 14.4 17.0 0.18 11.5 10.7 2.5 1 1 1 2 2 2 0 Right handed beta helix region Pectate_lyase_3 PF12708.2 GAM18934.1 - 0.023 14.8 4.9 0.16 12.1 3.4 2.3 1 1 0 1 1 1 0 Pectate lyase superfamily protein TIG PF01833.19 GAM18936.1 - 2.4e-57 190.9 142.3 2.6e-07 30.5 4.6 14.7 15 0 0 15 15 15 12 IPT/TIG domain EGF_2 PF07974.8 GAM18936.1 - 0.019 15.1 5.8 0.051 13.7 4.0 1.8 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 GAM18939.1 - 9.3e-23 80.0 81.3 8.2e-06 25.7 6.4 8.6 8 0 0 8 8 8 8 IPT/TIG domain PRKCSH_1 PF13015.1 GAM18939.1 - 0.0092 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CBM_X2 PF03442.9 GAM18939.1 - 0.14 11.9 10.5 0.91 9.3 0.1 5.1 5 0 0 5 5 5 0 Carbohydrate binding domain X2 Thymidylate_kin PF02223.12 GAM18940.1 - 3.5e-39 134.0 0.0 4.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase EMP24_GP25L PF01105.19 GAM18940.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ZZ PF00569.12 GAM18940.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type AMP-binding PF00501.23 GAM18941.1 - 4.4e-85 285.5 0.0 7.3e-85 284.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Myotub-related PF06602.9 GAM18942.1 - 1.1e-121 405.9 0.0 2.1e-121 405.0 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ank_2 PF12796.2 GAM18942.1 - 4.2e-30 103.9 0.2 1.2e-15 57.5 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM18942.1 - 1.3e-26 90.9 1.9 1.3e-06 27.8 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAM18942.1 - 1.6e-24 85.8 0.5 1.1e-07 32.1 0.0 5.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM18942.1 - 5.5e-22 75.6 0.5 0.00023 21.0 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 GAM18942.1 - 4.7e-20 71.1 0.7 1.1e-07 31.8 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) GRAM PF02893.15 GAM18942.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.9 1 0 0 1 1 1 0 GRAM domain Y_phosphatase3 PF13350.1 GAM18942.1 - 0.051 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family ECH_C PF13766.1 GAM18943.1 - 7.7e-42 142.1 0.5 1.3e-41 141.4 0.1 1.6 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 GAM18943.1 - 9.1e-26 90.4 0.0 1.7e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PTR PF12789.2 GAM18943.1 - 0.069 13.0 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage tail repeat like Frizzled PF01534.12 GAM18944.1 - 2.1e-08 33.3 15.3 3.2e-08 32.7 10.6 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 GAM18944.1 - 5.7e-07 28.7 14.8 1.1e-06 27.7 10.3 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM18944.1 - 8.2e-07 28.3 15.1 1.3e-06 27.7 10.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Ank_2 PF12796.2 GAM18945.1 - 0.014 15.7 0.1 3.7 7.9 0.0 4.2 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM18945.1 - 0.036 14.3 0.3 49 4.6 0.0 5.2 5 0 0 5 5 5 0 Ankyrin repeat SET PF00856.23 GAM18946.1 - 4.7e-12 46.5 0.0 4.7e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 SET domain Rubis-subs-bind PF09273.6 GAM18946.1 - 3.7e-05 23.6 3.6 0.00037 20.3 2.4 2.3 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Utp14 PF04615.8 GAM18947.1 - 0.59 8.2 34.2 0.75 7.8 23.7 1.2 1 0 0 1 1 1 0 Utp14 protein Dict-STAT-coil PF09267.5 GAM18948.1 - 2e-27 95.6 11.5 2e-27 95.6 7.9 2.9 4 0 0 4 4 4 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 GAM18948.1 - 3.2e-05 23.6 0.0 9.5e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain zf-CCCH_2 PF14608.1 GAM18949.1 - 0.0022 17.8 3.0 0.0041 17.0 2.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 GAM18949.1 - 0.15 11.7 3.3 0.3 10.8 2.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_4 PF13418.1 GAM18950.1 - 4.6e-13 48.7 3.6 0.00064 19.4 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM18950.1 - 1.1e-10 41.2 7.9 0.26 11.5 0.0 5.7 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 GAM18950.1 - 1.1e-08 34.4 9.8 0.25 10.9 0.0 5.4 5 1 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 GAM18950.1 - 1.4e-06 28.0 12.9 0.26 11.2 0.6 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 GAM18950.1 - 0.00037 20.1 5.9 0.73 9.7 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Rax2 PF12768.2 GAM18950.1 - 0.0046 16.1 3.9 0.075 12.2 0.0 3.4 2 2 0 3 3 3 1 Cortical protein marker for cell polarity BID PF06393.6 GAM18950.1 - 0.068 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) Kelch_3 PF13415.1 GAM18950.1 - 0.075 13.2 21.1 0.95 9.7 0.0 6.4 7 1 0 7 7 7 0 Galactose oxidase, central domain Fucokinase PF07959.7 GAM18951.1 - 5.3e-34 117.4 0.0 8e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.21 GAM18951.1 - 7.4e-08 32.3 0.1 2e-07 30.9 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM18951.1 - 2e-06 27.9 0.0 5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Kelch_6 PF13964.1 GAM18952.1 - 3.8e-10 39.5 5.4 0.007 16.4 0.0 5.1 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM18952.1 - 8.9e-10 38.4 3.3 0.0015 18.6 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM18952.1 - 4.2e-08 32.8 7.0 0.0007 19.3 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM18952.1 - 1.8e-06 27.3 6.9 0.013 15.0 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Rax2 PF12768.2 GAM18952.1 - 2.4e-05 23.7 1.0 0.00017 20.8 0.1 2.4 3 0 0 3 3 3 1 Cortical protein marker for cell polarity Kelch_2 PF07646.10 GAM18952.1 - 0.00014 21.4 4.8 1.1 9.0 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM18952.1 - 0.0073 16.2 11.3 0.11 12.5 0.3 4.4 5 0 0 5 5 5 2 Kelch motif LRR_4 PF12799.2 GAM18953.1 - 2.8e-13 49.1 18.0 2.7e-07 30.0 2.2 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 GAM18953.1 - 1.2e-09 37.9 2.1 3.1e-09 36.6 1.4 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 GAM18953.1 - 1.4e-07 31.1 12.3 0.00039 20.1 0.8 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 GAM18953.1 - 6.4e-05 22.6 17.3 0.08 13.0 0.4 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 GAM18953.1 - 0.0063 16.5 11.5 1.4 9.4 0.3 5.7 5 1 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 GAM18953.1 - 0.0097 15.8 13.2 1.1 9.5 0.1 4.7 4 1 1 5 5 5 2 Leucine Rich Repeat S_layer_N PF05123.7 GAM18953.1 - 0.46 10.0 8.4 0.77 9.3 5.9 1.4 1 1 0 1 1 1 0 S-layer like family, N-terminal region Secretin_N_2 PF07655.8 GAM18953.1 - 1.7 9.0 11.3 4.3 7.7 7.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Apc15p PF05841.6 GAM18953.1 - 8.2 7.1 11.6 1.5e+02 3.1 8.0 2.4 1 1 0 1 1 1 0 Apc15p protein NfeD PF01957.13 GAM18954.1 - 0.036 14.1 0.6 0.036 14.1 0.4 1.8 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2663 PF10864.3 GAM18954.1 - 0.099 12.8 1.8 0.2 11.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) CRPA PF05745.6 GAM18954.1 - 0.9 9.3 5.9 0.07 12.9 0.9 1.6 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tmemb_9 PF05434.6 GAM18954.1 - 2.6 7.7 5.1 2.8 7.6 0.0 2.4 1 1 1 2 2 2 0 TMEM9 DUF1771 PF08590.5 GAM18956.1 - 2.8e-15 56.0 7.8 1.1e-14 54.1 5.4 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 GAM18956.1 - 1.2e-13 50.2 1.1 3.3e-05 23.2 0.0 3.5 3 0 0 3 3 3 2 CUE domain Smr PF01713.16 GAM18956.1 - 1.1e-10 41.5 0.1 4.2e-10 39.6 0.1 2.1 1 0 0 1 1 1 1 Smr domain DUF3439 PF11921.3 GAM18956.1 - 0.097 12.4 3.9 0.26 11.0 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LsmAD PF06741.8 GAM18957.1 - 2e-22 79.0 5.6 2e-22 79.0 3.9 2.5 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 GAM18957.1 - 4.5e-12 45.7 0.0 1.8e-11 43.7 0.0 2.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 GAM18957.1 - 0.048 13.2 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 LSM domain PAM2 PF07145.10 GAM18957.1 - 0.17 11.4 7.4 3.3 7.4 0.6 3.3 1 1 1 2 2 2 0 Ataxin-2 C-terminal region EGF_2 PF07974.8 GAM18958.1 - 0.00013 22.0 10.5 0.00013 22.0 7.3 1.6 2 0 0 2 2 2 1 EGF-like domain MFS_1 PF07690.11 GAM18959.1 - 2.3e-13 49.5 26.2 6e-08 31.7 4.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 GAM18959.1 - 4.4e-10 38.8 20.8 3.7e-07 29.2 5.0 2.0 1 1 1 2 2 2 2 Nucleoside H+ symporter MFS_1_like PF12832.2 GAM18959.1 - 2.1e-08 33.8 3.7 2.1e-08 33.8 2.5 2.9 4 0 0 4 4 4 1 MFS_1 like family LacY_symp PF01306.14 GAM18959.1 - 9e-06 24.4 24.3 1.2e-05 24.0 8.0 2.2 1 1 1 2 2 2 2 LacY proton/sugar symporter DUF2052 PF09747.4 GAM18960.1 - 3.3e-12 46.7 36.5 3.3e-12 46.7 25.3 3.1 2 1 1 3 3 3 1 Coiled-coil domain containing protein (DUF2052) CitT PF12431.3 GAM18960.1 - 1.6 8.9 4.1 0.61 10.2 0.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator Ribosomal_60s PF00428.14 GAM18960.1 - 4.6 7.7 13.1 11 6.4 9.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Oxysterol_BP PF01237.13 GAM18962.1 - 0.13 10.7 0.1 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein CIMR PF00878.13 GAM18963.1 - 2e-09 37.3 3.2 3.9e-06 26.6 0.2 2.3 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 GAM18963.1 - 1.7e-06 27.5 0.4 2.6e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.10 GAM18963.1 - 5.2e-05 22.3 0.1 8.7e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 GAM18963.1 - 0.00029 20.1 8.2 0.021 14.0 5.7 2.7 1 1 0 1 1 1 1 Autophagy-related protein 27 DUF4013 PF13197.1 GAM18963.1 - 0.23 10.7 3.1 0.1 11.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) Trp_Tyr_perm PF03222.8 GAM18964.1 - 0.00029 19.7 0.7 0.00029 19.7 0.5 3.3 3 1 0 3 3 3 2 Tryptophan/tyrosine permease family Aa_trans PF01490.13 GAM18964.1 - 0.58 8.5 25.3 0.013 13.9 1.5 3.2 3 0 0 3 3 3 0 Transmembrane amino acid transporter protein FancD2 PF14631.1 GAM18965.1 - 5.7e-122 408.1 44.6 5.2e-106 355.2 12.6 6.0 2 2 2 4 4 4 3 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.1 GAM18965.1 - 0.0031 17.4 0.0 0.0031 17.4 0.0 4.3 5 1 1 6 6 6 1 FANCI solenoid 2 Annexin PF00191.15 GAM18966.1 - 7.5e-74 243.5 1.9 1.7e-21 75.8 0.1 4.1 4 0 0 4 4 4 4 Annexin Sporozoite_P67 PF05642.6 GAM18966.1 - 0.59 7.9 2.8 0.8 7.4 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HEAT PF02985.17 GAM18967.1 - 3.4e-15 54.6 1.7 0.0015 18.4 0.0 8.9 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 GAM18967.1 - 1.4e-12 47.6 0.0 0.16 12.2 0.0 5.4 3 2 1 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 GAM18967.1 - 2.3e-11 43.8 0.0 0.38 11.3 0.0 7.1 7 1 1 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM18967.1 - 2.9e-06 27.5 0.2 0.0025 18.1 0.0 5.0 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM18967.1 - 0.00026 20.4 1.0 0.003 16.9 0.0 3.3 2 2 0 2 2 2 1 CLASP N terminal IBN_N PF03810.14 GAM18967.1 - 0.0007 19.4 1.4 0.0072 16.2 0.2 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain B56 PF01603.15 GAM18967.1 - 0.0098 14.5 9.8 0.0072 14.9 3.8 2.8 2 1 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cnd1 PF12717.2 GAM18967.1 - 0.017 14.9 0.3 0.017 14.9 0.2 5.6 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 GLTP PF08718.6 GAM18967.1 - 0.038 14.0 0.3 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) Arm PF00514.18 GAM18967.1 - 0.067 13.0 0.0 5.8 6.8 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat polyprenyl_synt PF00348.12 GAM18968.1 - 2.7e-50 170.6 0.1 3.5e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase EF-hand_4 PF12763.2 GAM18969.1 - 1e-20 73.4 0.0 3.9e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.18 GAM18969.1 - 2.4e-20 73.0 0.0 4e-19 69.0 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAM18969.1 - 3.3e-07 30.2 0.0 8.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_1 PF00036.27 GAM18969.1 - 6.7e-06 25.0 0.3 2.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 EF hand Miro PF08477.8 GAM18969.1 - 0.00015 22.2 0.0 0.0095 16.4 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein EF-hand_8 PF13833.1 GAM18969.1 - 0.00044 19.8 0.1 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 GAM18969.1 - 0.002 18.2 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair GTP_EFTU PF00009.22 GAM18969.1 - 0.0033 16.8 0.0 0.018 14.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.1 GAM18969.1 - 0.026 14.3 0.1 0.12 12.3 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 GAM18969.1 - 0.052 12.9 0.1 0.17 11.3 0.1 1.8 1 0 0 1 1 1 0 EF hand AAA_28 PF13521.1 GAM18969.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM18969.1 - 0.11 12.0 0.0 3.9 6.8 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF1348 PF07080.6 GAM18970.1 - 6.1e-74 246.5 6.8 7.2e-74 246.3 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 GAM18970.1 - 1.8e-07 31.4 0.5 2.4e-07 31.0 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM18970.1 - 1.4e-05 25.1 0.1 2.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 GAM18970.1 - 0.0041 16.6 0.2 0.0058 16.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Y_phosphatase3 PF13350.1 GAM18971.1 - 6e-26 91.6 0.2 6.6e-15 55.7 0.0 2.5 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAM18971.1 - 1.7e-08 34.4 0.0 4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 GAM18971.1 - 9.4e-06 25.0 0.1 0.00011 21.6 0.0 2.4 2 1 0 2 2 2 1 Tyrosine phosphatase family Vps39_2 PF10367.4 GAM18972.1 - 1.1e-27 96.3 1.1 2.7e-27 95.0 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 GAM18972.1 - 4e-25 88.7 0.0 8.9e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 GAM18972.1 - 7.4e-07 28.8 15.8 1e-06 28.3 1.4 3.7 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_1 PF10366.4 GAM18972.1 - 0.00036 20.5 0.2 0.00036 20.5 0.1 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 DUF2175 PF09943.4 GAM18972.1 - 0.042 13.8 0.6 0.15 12.1 0.4 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_11 PF13414.1 GAM18972.1 - 0.84 9.3 4.7 2.3 7.9 0.3 3.2 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 GAM18972.1 - 0.87 9.6 5.8 3.7 7.7 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM18972.1 - 1.2 9.0 4.9 16 5.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 GAM18972.1 - 1.8 8.3 4.4 0.43 10.2 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.23 GAM18972.1 - 2.4 7.8 6.4 1.2 8.8 0.4 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 GAM18973.1 - 3.8e-13 48.8 31.2 3.8e-13 48.8 21.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TIG PF01833.19 GAM18976.1 - 3.8e-49 164.5 239.5 1.5e-06 28.1 5.1 21.0 13 6 7 21 21 21 15 IPT/TIG domain EGF_2 PF07974.8 GAM18976.1 - 1.1 9.5 12.5 2.5 8.3 8.7 1.6 1 0 0 1 1 1 0 EGF-like domain RRM_1 PF00076.17 GAM18977.1 - 1.4e-13 50.2 0.0 3.6e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 GAM18977.1 - 1.9e-13 49.8 0.0 5.1e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 GAM18977.1 - 9.9e-08 31.7 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 GAM18977.1 - 2e-07 30.7 0.3 4.1e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_6 PF14259.1 GAM18977.1 - 2.1e-07 30.8 0.0 8.9e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAM18977.1 - 0.14 10.6 48.2 0.0037 15.7 3.3 2.8 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 Ribosomal_L19e PF01280.15 GAM18978.1 - 2.7e-39 134.2 1.9 1.1e-37 129.0 0.4 2.9 2 1 1 3 3 3 2 Ribosomal protein L19e TM2 PF05154.11 GAM18979.1 - 1.6e-20 73.0 11.5 2.4e-20 72.5 8.0 1.2 1 0 0 1 1 1 1 TM2 domain FIBP PF05427.6 GAM18980.1 - 3e-65 220.8 0.8 5.2e-49 167.4 0.2 2.0 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) zf-RING_2 PF13639.1 GAM18981.1 - 2.8e-07 30.2 13.6 5.8e-07 29.2 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain PWI PF01480.12 GAM18981.1 - 4.7e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PWI domain zf-C3HC4 PF00097.20 GAM18981.1 - 8e-06 25.4 12.0 8e-06 25.4 8.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM18981.1 - 9.4e-05 22.4 9.6 0.00035 20.6 6.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM18981.1 - 0.0001 22.2 13.9 0.0001 22.2 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM18981.1 - 0.00013 21.5 7.3 0.00013 21.5 5.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM18981.1 - 0.012 15.2 10.0 0.038 13.7 6.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 GAM18981.1 - 0.017 14.9 4.3 0.045 13.5 3.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_U32 PF01136.14 GAM18981.1 - 0.045 12.6 0.1 0.073 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase family U32 DUF1644 PF07800.7 GAM18981.1 - 0.21 11.4 5.9 18 5.1 1.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.1 GAM18981.1 - 0.58 9.7 8.5 1.9 8.1 6.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 GAM18981.1 - 0.72 9.5 9.7 0.14 11.8 3.1 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Spt20 PF12090.3 GAM18981.1 - 1.1 8.5 7.7 0.25 10.6 0.3 2.5 2 1 0 2 2 2 0 Spt20 family Dicty_REP PF05086.7 GAM18982.1 - 0.0021 15.9 4.4 0.0032 15.3 3.1 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Pex14_N PF04695.8 GAM18982.1 - 0.014 15.4 2.8 0.033 14.2 0.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3254 PF11630.3 GAM18984.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) G-alpha PF00503.15 GAM18986.1 - 1.1e-124 416.1 5.8 1.3e-124 415.8 4.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM18986.1 - 1.2e-15 57.1 0.6 1.8e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 GAM18986.1 - 0.00044 20.7 0.6 0.13 12.8 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 GAM18986.1 - 0.00098 18.3 2.7 0.16 11.1 0.0 2.8 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM18986.1 - 0.016 15.1 0.5 0.42 10.5 0.4 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM18986.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0113 PF03657.8 GAM18986.1 - 0.07 12.7 0.2 0.87 9.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0113) XRN_N PF03159.13 GAM18987.1 - 2.9e-65 219.9 0.1 5.1e-65 219.1 0.1 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PITH PF06201.8 GAM18987.1 - 5.4e-22 78.1 3.8 5.4e-22 78.1 2.7 2.0 2 0 0 2 2 2 1 PITH domain RRM_1 PF00076.17 GAM18987.1 - 1.1e-17 63.4 0.0 4e-10 39.1 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM18987.1 - 2.9e-15 55.9 0.0 2.5e-08 33.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM18987.1 - 3.5e-06 26.7 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA_4 PF14555.1 GAM18987.1 - 0.00019 20.9 0.0 0.00047 19.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Nup35_RRM_2 PF14605.1 GAM18987.1 - 0.00054 19.6 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.1 GAM18987.1 - 0.004 16.8 0.4 0.01 15.5 0.2 1.8 2 0 0 2 2 2 1 Zinc knuckle Limkain-b1 PF11608.3 GAM18987.1 - 0.056 13.2 0.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Kinesin PF00225.18 GAM18988.1 - 1.3e-101 339.6 2.6 1.3e-101 339.6 1.8 2.1 2 0 0 2 2 2 1 Kinesin motor domain Ribosomal_S26e PF01283.14 GAM18989.1 - 8.7e-46 154.8 7.8 9.2e-46 154.7 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF2602 PF10782.4 GAM18989.1 - 0.18 11.6 1.8 0.54 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2602) Fer4_7 PF12838.2 GAM18989.1 - 0.59 10.5 4.4 5.2 7.5 3.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAM18989.1 - 1.4 8.8 6.0 2 8.2 1.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF1660 PF07874.6 GAM18989.1 - 9.1 6.6 6.0 19 5.6 0.6 2.1 1 1 1 2 2 2 0 Prophage protein (DUF1660) Syntaxin-18_N PF10496.4 GAM18990.1 - 7.1e-12 44.9 1.2 7.1e-12 44.9 0.9 2.9 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 GAM18990.1 - 1.7e-07 30.8 3.5 5e-07 29.3 1.0 2.7 3 0 0 3 3 3 1 SNARE domain TetR_C_8 PF14278.1 GAM18990.1 - 0.0084 16.4 3.2 0.021 15.2 0.2 2.8 3 0 0 3 3 3 1 Transcriptional regulator C-terminal region Carbpep_Y_N PF05388.6 GAM18990.1 - 0.27 11.4 3.8 0.28 11.3 0.1 2.7 3 1 1 4 4 4 0 Carboxypeptidase Y pro-peptide DUF948 PF06103.6 GAM18990.1 - 0.35 10.7 5.2 0.23 11.3 0.5 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2962 PF11176.3 GAM18990.1 - 1.6 8.2 10.0 0.037 13.5 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2962) DUF4422 PF14393.1 GAM18990.1 - 2.2 7.8 10.5 0.23 11.0 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4422) APG9 PF04109.11 GAM18991.1 - 7.5e-134 446.2 4.9 1.6e-133 445.1 3.4 1.5 1 0 0 1 1 1 1 Autophagy protein Apg9 WD40 PF00400.27 GAM18992.1 - 7.6e-65 212.6 17.4 5e-12 45.2 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 GAM18992.1 - 7e-43 146.1 7.8 1.7e-42 144.8 5.4 1.6 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 GAM18992.1 - 4.8e-06 25.0 10.0 0.0061 14.7 0.9 4.3 1 1 3 4 4 4 3 Nucleoporin Nup120/160 LisH PF08513.6 GAM18992.1 - 0.00034 20.2 0.1 0.001 18.7 0.1 1.9 1 0 0 1 1 1 1 LisH DUF3312 PF11768.3 GAM18992.1 - 0.028 12.6 0.0 0.051 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF3278 PF11683.3 GAM18992.1 - 0.044 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Nbas_N PF15492.1 GAM18992.1 - 0.045 12.8 0.4 2.2 7.3 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 GAM18992.1 - 0.11 10.7 0.0 0.25 9.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain TTL PF03133.10 GAM18993.1 - 1.4e-66 224.4 7.2 1.4e-66 224.4 5.0 2.5 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 GAM18993.1 - 0.00099 18.8 0.0 0.005 16.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAM18993.1 - 0.0018 18.1 0.2 2.5 7.9 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_YheCD PF14398.1 GAM18993.1 - 0.0044 15.8 4.2 0.0087 14.8 0.0 2.6 3 0 0 3 3 3 1 YheC/D like ATP-grasp RimK PF08443.6 GAM18993.1 - 0.012 15.1 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain tRNA-synt_2 PF00152.15 GAM18994.1 - 1.1e-87 293.9 0.2 1.3e-87 293.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM18994.1 - 2e-10 40.3 0.0 3.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAM18994.1 - 3.2e-09 36.3 0.0 1.7e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAM18994.1 - 0.036 13.6 0.2 7.9 6.0 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.20 GAM18995.1 - 1.6e-70 237.2 0.6 2.8e-70 236.4 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM18995.1 - 4.4e-36 124.2 0.0 4.4e-36 124.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.13 GAM18995.1 - 1.2e-23 82.7 2.1 1.9e-13 50.1 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 GAM18995.1 - 7.7e-09 34.9 1.1 3.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Mannitol_dh PF01232.18 GAM18995.1 - 0.056 13.3 0.9 0.14 12.0 0.7 1.7 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Nol1_Nop2_Fmu_2 PF13636.1 GAM18995.1 - 0.074 13.1 0.1 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 pre-rRNA processing and ribosome biogenesis CNP1 PF08750.6 GAM18995.1 - 0.13 12.0 2.0 0.5 10.0 0.1 2.3 2 0 0 2 2 2 0 CNP1-like family Patatin PF01734.17 GAM18996.1 - 2.3e-09 37.4 0.1 2.3e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2362 PF10154.4 GAM18996.1 - 0.056 12.0 16.2 0.086 11.4 11.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) HABP4_PAI-RBP1 PF04774.10 GAM18997.1 - 0.00035 21.0 1.5 0.00038 20.9 1.1 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family BUD22 PF09073.5 GAM18998.1 - 0.0021 17.2 4.3 0.0021 17.2 3.0 4.3 1 1 2 3 3 3 1 BUD22 UPF0086 PF01868.11 GAM18998.1 - 0.16 11.6 5.6 0.066 12.8 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function UPF0086 BRO1 PF03097.13 GAM18999.1 - 7.3e-25 87.5 0.3 8.7e-25 87.2 0.2 1.0 1 0 0 1 1 1 1 BRO1-like domain PseudoU_synth_2 PF00849.17 GAM19000.1 - 4.7e-22 78.5 0.0 6.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase zf-DHHC PF01529.15 GAM19002.1 - 1.5e-40 138.4 9.1 1.5e-40 138.4 6.3 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ycf1 PF05758.7 GAM19002.1 - 0.00024 18.9 0.2 0.00029 18.7 0.1 1.1 1 0 0 1 1 1 1 Ycf1 IncA PF04156.9 GAM19002.1 - 0.0011 18.5 5.0 0.0025 17.4 3.5 1.5 1 0 0 1 1 1 1 IncA protein Zip PF02535.17 GAM19002.1 - 0.054 12.5 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.5 GAM19002.1 - 0.093 12.5 3.7 0.21 11.3 2.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1272 PF06906.6 GAM19002.1 - 0.63 9.9 5.8 2 8.3 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) DUF4175 PF13779.1 GAM19002.1 - 1.6 6.3 16.9 2 5.9 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glyco_transf_49 PF13896.1 GAM19003.1 - 1.5e-37 129.4 2.7 2e-30 106.0 0.1 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM19003.1 - 6.5e-05 22.1 0.4 0.00012 21.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM19003.1 - 0.0025 17.4 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Coiled PF05710.7 GAM19004.1 - 0.022 15.2 11.8 0.023 15.1 8.2 1.1 1 0 0 1 1 1 0 Coiled coil SSP160 PF06933.6 GAM19004.1 - 6 4.7 10.1 6.5 4.6 7.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ammonium_transp PF00909.16 GAM19005.1 - 4e-100 335.0 20.3 4.8e-100 334.8 14.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DDE_Tnp_4 PF13359.1 GAM19007.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM19007.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain MerR_2 PF13591.1 GAM19008.1 - 0.094 12.3 0.9 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein Rap_GAP PF02145.10 GAM19009.1 - 7e-38 129.8 0.2 1.4e-37 128.9 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP RhoGAP PF00620.22 GAM19010.1 - 1.3e-30 106.0 2.4 1.5e-30 105.8 0.2 2.2 2 0 0 2 2 2 1 RhoGAP domain Rrf2 PF02082.15 GAM19010.1 - 0.059 13.4 1.3 0.27 11.3 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator MIT PF04212.13 GAM19011.1 - 1.1e-06 28.3 0.4 1.1e-06 28.3 0.3 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DUF3439 PF11921.3 GAM19011.1 - 0.12 12.0 3.3 0.23 11.2 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2935 PF11155.3 GAM19011.1 - 0.21 11.6 4.9 0.2 11.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) WD40 PF00400.27 GAM19013.1 - 1.2e-45 151.8 1.9 1.2e-11 43.9 0.4 9.9 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.7 GAM19013.1 - 7.4e-25 86.9 0.0 1.3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 GAM19013.1 - 2.3e-10 40.5 0.2 0.016 14.9 0.0 4.9 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 GAM19013.1 - 0.0018 17.8 0.0 20 4.9 0.0 5.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 GAM19013.1 - 0.0025 16.9 0.1 13 4.8 0.0 4.2 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 GAM19013.1 - 0.0033 16.3 0.0 0.19 10.6 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Nup160 PF11715.3 GAM19013.1 - 0.028 12.5 0.6 0.46 8.5 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Utp21 PF04192.7 GAM19013.1 - 0.035 13.2 0.1 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain RRM_5 PF13893.1 GAM19013.1 - 0.039 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQQ_3 PF13570.1 GAM19013.1 - 0.69 10.2 3.1 2.3 8.5 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain Med4 PF10018.4 GAM19014.1 - 1.3e-28 99.6 4.4 1.3e-28 99.6 3.1 3.1 3 1 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2453 PF10507.4 GAM19014.1 - 0.52 10.1 2.1 0.43 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) AAA_23 PF13476.1 GAM19014.1 - 2 8.6 9.3 1.7 8.9 1.0 2.3 2 0 0 2 2 2 0 AAA domain PAT1 PF09770.4 GAM19014.1 - 8 4.5 38.1 1.3 7.1 12.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MAM33 PF02330.11 GAM19015.1 - 8.9e-05 22.3 18.1 0.23 11.2 8.7 3.1 2 1 0 3 3 3 2 Mitochondrial glycoprotein FimP PF09766.4 GAM19015.1 - 0.00057 19.0 2.4 0.00077 18.6 1.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein FLO_LFY PF01698.11 GAM19015.1 - 0.057 12.2 7.0 0.081 11.7 4.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FixO PF02433.10 GAM19015.1 - 0.14 11.5 2.3 0.24 10.7 1.6 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Trypan_PARP PF05887.6 GAM19015.1 - 1.2 8.9 15.2 1.9 8.3 10.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Paf1 PF03985.8 GAM19015.1 - 2.6 6.6 15.5 3.8 6.1 10.7 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 GAM19015.1 - 4.7 5.0 17.5 5.7 4.7 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM19015.1 - 6.3 5.1 18.8 8.3 4.7 13.1 1.1 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 GAM19016.1 - 7.8e-57 192.3 0.0 1.3e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19016.1 - 3.9e-56 190.0 0.0 5.9e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.14 GAM19016.1 - 2.6e-44 151.1 0.1 4.5e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM19016.1 - 5.7e-20 71.3 1.6 2.1e-19 69.5 1.1 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif Pox_ser-thr_kin PF05445.6 GAM19016.1 - 0.031 13.0 0.6 3.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 GAM19016.1 - 0.035 13.6 0.0 0.12 11.9 0.0 1.9 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 GAM19016.1 - 0.039 13.6 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM19016.1 - 0.052 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAM19016.1 - 0.055 12.5 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bcl-2I13 PF12201.3 GAM19016.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing NUDIX PF00293.23 GAM19017.1 - 5.6e-17 61.6 0.0 9.1e-15 54.4 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain FYVE PF01363.16 GAM19018.1 - 6.6e-09 35.5 5.7 1.3e-08 34.5 4.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 GAM19018.1 - 0.00041 20.2 4.4 0.00041 20.2 3.1 1.8 2 0 0 2 2 2 1 FYVE-type zinc finger Syntaxin_2 PF14523.1 GAM19018.1 - 0.043 13.8 4.8 0.1 12.6 0.7 2.5 2 0 0 2 2 2 0 Syntaxin-like protein DUF3516 PF12029.3 GAM19018.1 - 0.052 12.3 0.1 0.077 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) IBR PF01485.16 GAM19018.1 - 0.056 13.3 4.4 0.16 11.8 3.1 1.7 1 0 0 1 1 1 0 IBR domain Herpes_UL36 PF03586.8 GAM19018.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Sec8_exocyst PF04048.9 GAM19018.1 - 0.11 12.0 2.9 0.18 11.4 0.5 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain OB_NTP_bind PF07717.11 GAM19019.1 - 9.1e-26 89.9 0.0 2.6e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM19019.1 - 1.8e-22 79.3 0.0 3.6e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM19019.1 - 1.3e-12 47.4 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM19019.1 - 1.1e-07 31.5 0.1 2.8e-07 30.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM19019.1 - 6.7e-05 23.0 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM19019.1 - 0.0016 18.1 0.3 0.0068 16.1 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 GAM19019.1 - 0.015 15.6 0.2 0.16 12.2 0.1 2.4 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 GAM19019.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 GAM19019.1 - 0.018 14.8 0.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 GAM19019.1 - 0.035 13.8 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.17 GAM19019.1 - 0.058 12.8 0.5 0.23 10.8 0.1 2.2 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Cellulose_synt PF03552.9 GAM19021.1 - 6.6e-26 90.8 4.0 1.5e-15 56.6 1.2 3.5 2 1 1 3 3 3 3 Cellulose synthase Glyco_tranf_2_3 PF13641.1 GAM19021.1 - 3.3e-24 85.9 0.0 1.2e-23 84.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM19021.1 - 4.2e-22 78.7 0.1 4.2e-22 78.7 0.1 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 GAM19021.1 - 8.7e-09 35.2 0.0 2.6e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 GAM19021.1 - 5.7e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Pentapeptide PF00805.17 GAM19022.1 - 4.6e-29 99.1 18.4 8.8e-10 37.6 0.3 4.2 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 GAM19022.1 - 1.4e-18 66.4 2.1 2.6e-10 39.9 0.0 2.6 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 GAM19022.1 - 1.1e-14 54.3 0.0 2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.1 GAM19022.1 - 1.7e-12 46.9 0.0 4.7e-05 23.1 0.0 3.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) CfAFP PF05264.6 GAM19022.1 - 0.042 13.6 0.3 0.042 13.6 0.2 2.3 2 1 0 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) tRNA_NucTran2_2 PF13735.1 GAM19022.1 - 0.055 13.2 0.3 0.097 12.4 0.2 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative YjgP_YjgQ PF03739.9 GAM19023.1 - 0.00078 18.2 0.7 0.00094 18.0 0.5 1.1 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family DUF1183 PF06682.7 GAM19023.1 - 0.021 14.4 4.3 0.023 14.3 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2371 PF10177.4 GAM19023.1 - 0.1 12.4 0.2 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Spore_YhcN_YlaJ PF09580.5 GAM19023.1 - 1.7 8.7 9.8 1.8 8.6 6.8 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) WBP-1 PF11669.3 GAM19023.1 - 4.9 7.2 7.5 54 3.9 5.2 2.1 1 1 0 1 1 1 0 WW domain-binding protein 1 Sulfotransfer_2 PF03567.9 GAM19024.1 - 5e-13 49.3 0.5 1.1e-12 48.1 0.4 1.6 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM19024.1 - 2e-09 36.6 2.9 1.9e-08 33.4 0.3 2.8 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase PIG-P PF08510.7 GAM19024.1 - 0.045 13.3 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 PIG-P MAPEG PF01124.13 GAM19024.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 MAPEG family Sulfotransfer_1 PF00685.22 GAM19024.1 - 0.19 10.9 2.9 0.36 10.0 0.3 2.5 2 1 0 2 2 2 0 Sulfotransferase domain UCH_1 PF13423.1 GAM19025.1 - 7e-51 173.4 11.3 7e-51 173.4 7.9 2.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 GAM19025.1 - 2.2e-26 93.1 1.4 2.4e-25 89.7 0.0 2.9 3 0 0 3 3 3 1 Exonuclease UCH PF00443.24 GAM19025.1 - 3.4e-09 36.2 13.0 3.4e-09 36.2 9.0 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase BAF1_ABF1 PF04684.8 GAM19025.1 - 8.9e-05 21.5 17.7 8.9e-05 21.5 12.2 3.3 2 1 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 GAM19025.1 - 0.0031 16.5 4.0 0.0031 16.5 2.8 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter YjeF_N PF03853.10 GAM19025.1 - 0.068 12.7 0.3 0.21 11.1 0.2 1.8 1 0 0 1 1 1 0 YjeF-related protein N-terminus TFIIA PF03153.8 GAM19025.1 - 0.34 10.7 36.9 0.95 9.2 12.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.8 GAM19025.1 - 0.49 9.8 13.3 1 8.7 1.2 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FAM60A PF15396.1 GAM19025.1 - 1.8 8.2 18.0 2.1 8.0 2.3 2.4 2 0 0 2 2 2 0 Protein Family FAM60A DDE_3 PF13358.1 GAM19026.1 - 4.2e-17 62.2 0.0 5.2e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease TMEM154 PF15102.1 GAM19029.1 - 1.8e-05 24.5 0.0 3.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.6 GAM19029.1 - 0.013 14.6 2.5 0.023 13.8 1.7 1.6 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Protocadherin PF08374.6 GAM19029.1 - 0.035 13.7 0.0 0.035 13.7 0.0 2.2 3 0 0 3 3 3 0 Protocadherin DUF912 PF06024.7 GAM19029.1 - 0.041 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) P12 PF12669.2 GAM19029.1 - 0.046 13.9 3.0 2.5 8.3 0.3 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family EphA2_TM PF14575.1 GAM19029.1 - 0.053 13.9 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain NOA36 PF06524.7 GAM19029.1 - 0.22 10.7 13.0 0.28 10.3 9.0 1.2 1 0 0 1 1 1 0 NOA36 protein Fst_toxin PF13955.1 GAM19029.1 - 0.35 10.5 5.5 0.65 9.7 3.8 1.4 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system zf-CCHH PF10283.4 GAM19030.1 - 0.1 12.4 4.2 1 9.2 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif AMP-binding PF00501.23 GAM19031.1 - 5.5e-95 318.1 0.0 7.2e-95 317.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM19031.1 - 8.8e-15 55.4 0.0 2e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Anoctamin PF04547.7 GAM19032.1 - 2e-93 313.4 22.1 3e-93 312.9 15.3 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Ion_trans PF00520.26 GAM19033.1 - 0.00022 20.5 1.0 0.16 11.1 0.4 2.2 2 0 0 2 2 2 2 Ion transport protein Tetraspannin PF00335.15 GAM19033.1 - 0.054 12.7 2.1 0.33 10.1 1.5 2.0 1 1 0 1 1 1 0 Tetraspanin family FNIP PF05725.7 GAM19034.1 - 2e-95 312.5 15.7 1.6e-14 53.5 0.1 9.6 8 1 0 9 9 9 9 FNIP Repeat Tecti-min-caps PF09300.5 GAM19034.1 - 0.15 11.8 0.7 50 3.7 0.0 4.5 5 0 0 5 5 5 0 Tectiviridae, minor capsid TRAPP PF04051.11 GAM19035.1 - 1.4e-43 147.9 0.0 1.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FoP_duplication PF13865.1 GAM19036.1 - 0.0023 18.3 32.1 0.1 13.0 20.5 3.0 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 M_domain PF12938.2 GAM19036.1 - 10 5.8 9.2 14 5.3 6.4 1.3 1 0 0 1 1 1 0 M domain of GW182 SNF2_N PF00176.18 GAM19037.1 - 1.1e-78 264.0 0.0 1.1e-78 264.0 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 GAM19037.1 - 1.3e-32 111.9 2.1 1.3e-32 111.9 1.5 3.2 3 1 0 3 3 3 1 SLIDE Helicase_C PF00271.26 GAM19037.1 - 1.5e-17 63.2 0.0 8.7e-17 60.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HAND PF09110.6 GAM19037.1 - 4e-12 46.5 5.4 4e-12 46.5 3.8 5.1 3 2 1 4 4 4 1 HAND DEAD PF00270.24 GAM19037.1 - 4.3e-06 26.3 0.0 1.9e-05 24.2 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.1 GAM19037.1 - 0.0003 20.8 16.1 0.0003 20.8 11.2 4.1 3 1 1 4 4 4 1 DNA-binding domain Ribosomal_L34 PF00468.12 GAM19038.1 - 3.3e-17 61.8 6.3 4.8e-17 61.3 4.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 Tox-MPTase3 PF15639.1 GAM19038.1 - 0.015 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 3 SHNi-TPR PF10516.4 GAM19038.1 - 0.073 12.3 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 SHNi-TPR zf-CSL PF05207.8 GAM19039.1 - 9.4e-19 66.6 2.4 1.5e-18 66.0 1.7 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 GAM19039.1 - 4.2e-18 64.8 0.4 7.1e-18 64.1 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain KRAB PF01352.22 GAM19039.1 - 0.069 12.6 0.1 0.17 11.3 0.1 1.7 1 0 0 1 1 1 0 KRAB box CLU PF13236.1 GAM19040.1 - 1e-87 293.1 0.0 2e-87 292.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM19040.1 - 4.4e-47 160.1 2.3 5.5e-47 159.8 0.1 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 GAM19040.1 - 1.4e-27 95.4 4.7 7e-10 38.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.1 GAM19040.1 - 8e-23 80.3 0.7 6.4e-22 77.5 0.4 2.6 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 GAM19040.1 - 4e-22 77.4 0.3 1.9e-08 33.9 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM19040.1 - 1.1e-12 47.3 7.1 5.7e-08 32.2 0.1 3.2 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAM19040.1 - 5.8e-08 32.0 8.2 0.012 15.4 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM19040.1 - 6.8e-07 28.6 8.2 0.11 12.1 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM19040.1 - 0.00011 21.7 5.5 12 5.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM19040.1 - 0.00012 22.0 1.7 0.0093 16.0 0.1 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAM19040.1 - 0.00073 19.1 9.8 0.44 10.4 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM19040.1 - 0.028 15.0 1.1 16 6.3 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM19040.1 - 0.05 13.8 0.1 25 5.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM19041.1 - 1.3e-08 34.3 0.7 1.2e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 GAM19041.1 - 6.3e-08 33.0 0.0 0.0046 17.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM19041.1 - 1.3e-07 30.9 0.8 1.1e-05 24.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM19041.1 - 2.2e-07 31.1 0.2 0.0006 20.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM19041.1 - 3e-07 29.8 0.2 8.3e-05 22.2 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM19041.1 - 1.6e-05 25.1 0.0 0.37 11.5 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM19041.1 - 0.00021 20.8 0.0 0.31 10.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM19041.1 - 0.00099 18.9 0.1 0.41 10.5 0.0 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM19041.1 - 0.017 14.8 0.0 19 5.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM19041.1 - 0.018 14.8 0.2 0.9 9.4 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 GAM19041.1 - 0.029 14.2 0.0 0.35 10.8 0.0 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat PCNA_N PF00705.13 GAM19042.1 - 7.9e-06 25.3 1.6 1.7e-05 24.2 0.1 2.1 3 0 0 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 GAM19042.1 - 0.0002 20.5 2.0 0.00029 20.0 1.4 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 GAM19042.1 - 0.00029 19.6 6.3 0.018 13.8 0.3 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 zf-CCCH PF00642.19 GAM19043.1 - 0.002 17.7 2.0 0.0042 16.7 1.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Phage_rep_org_N PF09681.5 GAM19043.1 - 0.98 9.0 0.0 0.98 9.0 0.0 2.9 3 1 0 3 3 3 0 N-terminal phage replisome organiser (Phage_rep_org_N) RNase_H2_suC PF08615.6 GAM19044.1 - 0.004 16.9 0.0 0.004 16.9 0.0 2.0 2 1 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ribosomal_L37ae PF01780.14 GAM19045.1 - 5.1e-40 135.2 8.3 5.6e-40 135.1 5.7 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 GAM19045.1 - 0.0014 18.3 1.8 0.0021 17.8 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 GAM19045.1 - 0.0029 17.0 1.7 1.1 8.8 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 GAM19045.1 - 0.047 13.9 0.3 1.8 9.0 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain OrfB_Zn_ribbon PF07282.6 GAM19045.1 - 0.059 13.0 0.8 0.086 12.5 0.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C4_ClpX PF06689.8 GAM19045.1 - 0.069 12.6 2.4 0.077 12.5 0.1 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-FCS PF06467.9 GAM19045.1 - 0.15 11.7 1.8 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Zn-ribbon_8 PF09723.5 GAM19045.1 - 0.23 11.4 1.4 0.54 10.2 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain G-alpha PF00503.15 GAM19046.1 - 4.5e-13 48.6 17.8 9.5e-13 47.5 11.9 1.9 1 1 0 1 1 1 1 G-protein alpha subunit G-gamma PF00631.17 GAM19046.1 - 1.8e-05 24.3 0.1 4.9e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 GGL domain Spectrin PF00435.16 GAM19046.1 - 0.65 10.3 8.0 2.9 8.2 1.2 2.8 2 1 0 2 2 2 0 Spectrin repeat MCPsignal PF00015.16 GAM19046.1 - 1.8 8.0 7.3 0.11 12.0 0.7 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRR_4 PF12799.2 GAM19048.1 - 3.4e-13 48.8 11.3 1.1e-06 28.0 0.3 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM19048.1 - 4.4e-10 39.1 16.9 1.1e-06 28.2 2.2 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 GAM19048.1 - 7.4e-09 35.3 0.3 2.4e-08 33.7 0.2 1.8 1 1 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 GAM19048.1 - 4.3e-05 23.0 7.2 9.7 6.9 0.2 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 GAM19048.1 - 0.00011 21.7 10.9 4.2 7.7 0.1 4.5 3 1 1 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 GAM19048.1 - 1.9 8.8 11.8 22 5.4 0.1 5.0 3 1 2 5 5 5 0 Leucine Rich repeat UQ_con PF00179.21 GAM19050.1 - 2.1e-22 79.0 0.0 3.6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM19050.1 - 0.0086 15.9 0.4 0.092 12.6 0.0 2.3 2 0 0 2 2 2 1 RWD domain zf-RanBP PF00641.13 GAM19050.1 - 0.058 12.5 1.1 0.11 11.5 0.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others TpcC PF12642.2 GAM19050.1 - 0.078 12.5 1.0 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 Conjugative transposon protein TcpC HSF_DNA-bind PF00447.12 GAM19051.1 - 3.7e-28 97.7 0.9 3.7e-28 97.7 0.6 3.9 4 2 0 4 4 4 1 HSF-type DNA-binding HEAT_2 PF13646.1 GAM19052.1 - 4.2e-09 36.5 0.0 0.043 14.1 0.0 5.9 4 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 GAM19052.1 - 1.1e-08 34.3 4.6 0.072 13.2 0.1 5.5 5 0 0 5 5 5 3 HEAT repeat RimK PF08443.6 GAM19054.1 - 0.00064 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Lamp PF01299.12 GAM19055.1 - 0.1 11.6 4.9 0.19 10.8 3.4 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) AMP-binding PF00501.23 GAM19056.1 - 2.2e-90 303.0 0.0 2.9e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM19056.1 - 9.2e-13 48.9 0.1 3.4e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Dynein_IC2 PF11540.3 GAM19056.1 - 0.07 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 Ras PF00071.17 GAM19057.1 - 1.4e-39 135.0 0.2 1.7e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19057.1 - 3.9e-12 46.7 0.0 6.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19057.1 - 5e-06 25.8 0.1 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM19057.1 - 0.00043 19.7 0.0 0.00054 19.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Peptidase_M29 PF02073.10 GAM19057.1 - 0.043 12.5 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) bZIP_1 PF00170.16 GAM19058.1 - 6.5e-11 42.0 13.3 6.5e-11 42.0 9.2 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.12 GAM19058.1 - 4.9e-07 29.9 11.1 4.9e-07 29.9 7.7 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.10 GAM19058.1 - 0.0011 18.7 11.5 0.0011 18.7 8.0 2.1 2 0 0 2 2 2 1 Basic region leucine zipper UPF0184 PF03670.8 GAM19058.1 - 0.0055 16.8 1.8 0.0055 16.8 1.3 2.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0184) Acetyltransf_1 PF00583.19 GAM19059.1 - 1e-10 41.4 0.0 4.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family U-box PF04564.10 GAM19059.1 - 3.3e-10 39.7 0.0 8.2e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain Acetyltransf_7 PF13508.1 GAM19059.1 - 6.8e-09 35.7 0.0 2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 GAM19059.1 - 6.5e-07 29.0 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM19059.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Acetyltransf_10 PF13673.1 GAM19059.1 - 0.0012 18.9 0.0 0.0064 16.6 0.0 2.3 3 1 0 3 3 1 1 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.1 GAM19059.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 GAM19059.1 - 0.0013 18.1 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FR47 PF08445.5 GAM19059.1 - 0.004 16.8 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein zf-RING_UBOX PF13445.1 GAM19059.1 - 0.0046 16.6 0.0 0.017 14.8 0.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger Acetyltransf_3 PF13302.1 GAM19059.1 - 0.017 15.3 0.0 0.094 12.8 0.0 2.1 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C3HC4 PF00097.20 GAM19059.1 - 0.018 14.6 0.0 0.044 13.4 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM19059.1 - 0.024 14.4 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAM19059.1 - 0.043 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_8 PF13523.1 GAM19059.1 - 0.046 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_5 PF14634.1 GAM19059.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Flavoprotein PF02441.14 GAM19059.1 - 0.089 12.4 0.1 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavoprotein G-alpha PF00503.15 GAM19059.1 - 0.19 10.3 3.5 0.12 11.0 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Dicty_CAR PF05462.6 GAM19060.1 - 4e-10 39.0 23.1 5.2e-10 38.7 16.0 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.10 GAM19060.1 - 2e-07 30.0 9.9 2.5e-07 29.6 6.9 1.1 1 0 0 1 1 1 1 Ocular albinism type 1 protein 7tm_2 PF00002.19 GAM19060.1 - 5.7e-06 25.5 17.0 8.1e-06 25.0 11.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GST_N_2 PF13409.1 GAM19061.1 - 1.5e-20 72.9 0.0 2.7e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM19061.1 - 2.2e-09 37.0 0.0 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM19061.1 - 2.1e-06 27.8 0.0 3.8e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM19061.1 - 1.7e-05 25.2 0.0 3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM19061.1 - 0.0001 22.1 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Coiled PF05710.7 GAM19062.1 - 9.5 6.7 17.3 14 6.2 12.0 1.3 1 1 0 1 1 1 0 Coiled coil RRM_1 PF00076.17 GAM19063.1 - 1e-15 57.0 0.0 1.9e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19063.1 - 2.9e-11 43.1 0.0 5.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19063.1 - 1.2e-09 37.8 0.0 1.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 GAM19063.1 - 4.8e-07 29.4 2.6 1.1e-06 28.3 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 GAM19063.1 - 0.0029 17.0 0.5 0.0049 16.3 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1084 PF06454.6 GAM19064.1 - 5.4e-75 252.0 19.6 6.6e-75 251.7 13.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Arf PF00025.16 GAM19065.1 - 1.1e-66 223.3 0.1 1.2e-66 223.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM19065.1 - 1.7e-14 53.4 0.0 2.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM19065.1 - 7.5e-14 51.4 0.1 8.4e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19065.1 - 1.7e-11 44.6 0.0 2.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM19065.1 - 2.8e-09 36.4 0.0 3.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM19065.1 - 5.6e-09 35.1 2.5 2.8e-07 29.5 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 GAM19065.1 - 4.3e-06 26.6 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 GAM19065.1 - 0.0033 16.2 0.1 0.1 11.3 0.0 2.1 2 0 0 2 2 2 1 ArgK protein 6PF2K PF01591.13 GAM19065.1 - 0.023 13.7 0.4 0.1 11.6 0.3 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.22 GAM19065.1 - 0.029 14.6 0.1 0.084 13.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Vmethyltransf PF01660.12 GAM19065.1 - 0.053 12.1 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase AAA_14 PF13173.1 GAM19065.1 - 0.13 12.1 0.1 0.48 10.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM19065.1 - 0.14 12.0 0.2 0.49 10.2 0.1 1.8 1 1 1 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 GAM19066.1 - 0.0032 16.7 9.6 0.0032 16.7 6.7 3.1 2 1 1 4 4 4 2 Reovirus sigma C capsid protein HALZ PF02183.13 GAM19066.1 - 0.051 13.3 0.4 0.051 13.3 0.3 11.5 6 4 3 10 10 10 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.5 GAM19066.1 - 2.2 8.1 13.6 0.89 9.3 0.1 5.4 5 1 1 6 6 6 0 DASH complex subunit Dam1 FNIP PF05725.7 GAM19067.1 - 1.4e-67 223.3 15.7 4.4e-13 48.9 0.4 9.1 7 2 1 9 9 9 8 FNIP Repeat PPR_1 PF12854.2 GAM19067.1 - 0.059 12.8 0.1 0.18 11.2 0.0 1.9 1 0 0 1 1 1 0 PPR repeat FNIP PF05725.7 GAM19068.1 - 3.1e-74 244.6 15.0 1.2e-13 50.7 0.0 9.2 7 1 0 8 8 8 8 FNIP Repeat Ras PF00071.17 GAM19069.1 - 1.3e-65 219.7 0.1 1.5e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19069.1 - 3.3e-20 72.7 0.0 5.6e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19069.1 - 2.7e-15 56.0 0.1 3.5e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM19069.1 - 1.6e-06 27.4 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM19069.1 - 5.4e-06 25.9 0.1 1.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM19069.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM19069.1 - 0.00069 18.8 0.0 0.002 17.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 GAM19069.1 - 0.0087 15.2 0.1 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAM19069.1 - 0.019 13.6 0.9 4.8 5.7 0.1 2.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 GAM19069.1 - 0.033 13.7 0.1 0.1 12.1 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM19069.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF3963 PF13124.1 GAM19069.1 - 0.067 12.9 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_5 PF07728.9 GAM19069.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM PF00493.18 GAM19069.1 - 0.081 11.7 0.0 0.21 10.3 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family AAA_22 PF13401.1 GAM19069.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 GAM19069.1 - 0.11 12.6 0.1 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-DHHC PF01529.15 GAM19070.1 - 5e-24 84.6 21.1 5e-24 84.6 14.6 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Caprin-1_C PF12287.3 GAM19070.1 - 0.085 12.2 0.6 0.12 11.7 0.4 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term eIF3g PF12353.3 GAM19070.1 - 0.13 12.1 8.9 0.22 11.4 6.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF1272 PF06906.6 GAM19070.1 - 0.24 11.2 8.0 0.49 10.2 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF373 PF04123.8 GAM19070.1 - 5.1 6.0 6.4 4.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Ni_hydr_CYTB PF01292.15 GAM19070.1 - 6.2 6.1 14.9 10 5.4 0.6 3.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Ank_2 PF12796.2 GAM19071.1 - 1.4e-81 268.8 12.0 1.4e-20 73.4 0.1 3.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM19071.1 - 9.6e-40 132.4 1.4 6.6e-07 28.8 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 GAM19071.1 - 2.2e-34 114.0 2.4 6e-06 25.9 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 GAM19071.1 - 5.5e-33 112.2 9.4 2.7e-11 43.3 1.1 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM19071.1 - 8.2e-31 105.8 8.2 1.2e-12 47.9 0.1 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 GAM19071.1 - 8e-30 103.5 9.2 8e-30 103.5 6.4 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Nicastrin PF05450.10 GAM19072.1 - 1.3e-30 106.4 2.1 2.3e-30 105.6 1.5 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 GAM19072.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 EB PF01683.13 GAM19072.1 - 0.19 11.8 1.6 0.29 11.2 0.1 2.0 2 0 0 2 2 2 0 EB module Dickkopf_N PF04706.7 GAM19072.1 - 0.6 10.3 2.9 0.37 11.0 0.4 1.8 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Rap_GAP PF02145.10 GAM19073.1 - 3.2e-31 108.1 0.2 9.8e-31 106.5 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP Abhydrolase_6 PF12697.2 GAM19074.1 - 2.3e-33 115.9 0.0 2.8e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM19074.1 - 3.9e-29 101.8 0.0 5.4e-28 98.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM19074.1 - 1.4e-13 50.8 0.0 2.9e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM19074.1 - 7.7e-06 25.7 0.1 3.3e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 GAM19074.1 - 7.8e-05 22.0 0.0 0.059 12.6 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Thioesterase PF00975.15 GAM19074.1 - 0.0013 19.0 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.3 GAM19074.1 - 0.0015 18.3 0.0 0.0056 16.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 GAM19074.1 - 0.0015 18.0 0.4 0.043 13.2 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 GAM19074.1 - 0.004 16.6 0.0 0.0077 15.6 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 GAM19074.1 - 0.016 14.7 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.9 GAM19074.1 - 0.029 12.8 0.0 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.16 GAM19074.1 - 0.029 13.5 0.1 0.72 9.0 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.8 GAM19074.1 - 0.094 12.2 0.1 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein LRR_6 PF13516.1 GAM19075.1 - 5.9e-24 81.4 41.7 0.0083 16.0 0.0 12.2 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.2 GAM19075.1 - 6.1e-06 25.7 36.5 0.24 11.0 0.5 8.9 5 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM19075.1 - 0.00082 19.0 29.8 5.1 7.5 0.1 11.5 9 1 2 11 11 11 1 Leucine Rich Repeat Ank_2 PF12796.2 GAM19076.1 - 1.4e-55 185.6 0.4 2.9e-22 78.7 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM19076.1 - 2e-41 137.7 3.0 1.4e-10 40.4 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 GAM19076.1 - 6.4e-39 131.6 2.7 8.9e-09 35.6 0.0 6.9 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19076.1 - 4.2e-37 125.3 6.6 2.6e-10 40.1 0.1 6.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19076.1 - 2e-32 107.9 4.1 3.7e-06 26.6 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat MATH PF00917.21 GAM19076.1 - 6.9e-21 74.6 4.0 1.3e-13 51.2 0.4 3.8 4 1 0 4 4 4 2 MATH domain PSK PF06404.7 GAM19076.1 - 0.54 11.0 6.2 0.17 12.6 0.2 2.8 2 1 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Med11 PF10280.4 GAM19077.1 - 4.6e-06 26.6 0.2 5.1e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein GRAS PF03514.9 GAM19077.1 - 0.049 12.3 0.1 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family OspE PF02471.12 GAM19077.1 - 0.068 13.0 0.0 0.096 12.5 0.0 1.5 1 1 0 1 1 1 0 Borrelia outer surface protein E Pkinase PF00069.20 GAM19078.1 - 1.2e-51 175.3 0.5 1.2e-51 175.3 0.3 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19078.1 - 5.1e-32 110.9 0.1 8.8e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.11 GAM19078.1 - 2.9e-13 49.1 3.0 2.8e-12 45.9 1.4 2.3 2 0 0 2 2 2 1 ANTH domain Kinase-like PF14531.1 GAM19078.1 - 1.7e-06 27.2 0.0 2.3e-05 23.4 0.0 2.2 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 GAM19078.1 - 7.6e-06 25.8 0.0 0.0041 16.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM19078.1 - 0.00065 18.8 0.7 0.0012 17.8 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Synaptobrevin PF00957.16 GAM19079.1 - 3.7e-30 103.3 6.5 4.2e-30 103.1 4.5 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 GAM19079.1 - 0.0035 17.3 3.3 0.006 16.6 2.3 1.4 1 1 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3675 PF12428.3 GAM19079.1 - 0.0053 16.9 0.1 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3675) Rifin_STEVOR PF02009.11 GAM19079.1 - 0.0097 15.5 0.9 0.013 15.1 0.6 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF4064 PF13273.1 GAM19079.1 - 0.018 15.1 1.9 0.019 15.0 0.8 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Bap31 PF05529.7 GAM19079.1 - 0.019 14.3 0.8 0.022 14.2 0.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Prominin PF05478.6 GAM19079.1 - 0.02 12.4 1.1 0.027 12.0 0.8 1.2 1 0 0 1 1 1 0 Prominin DUF2207 PF09972.4 GAM19079.1 - 0.088 11.3 0.1 0.081 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3671 PF12420.3 GAM19079.1 - 0.097 12.6 1.3 0.19 11.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function Tropomyosin PF00261.15 GAM19079.1 - 0.11 11.6 0.8 0.12 11.3 0.5 1.0 1 0 0 1 1 1 0 Tropomyosin Fzo_mitofusin PF04799.8 GAM19079.1 - 0.14 11.5 1.9 0.23 10.8 1.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region GAT PF03127.9 GAM19079.1 - 0.2 11.6 1.8 0.25 11.3 1.2 1.2 1 0 0 1 1 1 0 GAT domain NPV_P10 PF05531.7 GAM19079.1 - 1.6 9.0 5.8 7.5 6.8 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GP41 PF00517.12 GAM19079.1 - 1.6 8.2 8.4 2.2 7.7 5.8 1.4 1 1 0 1 1 1 0 Retroviral envelope protein HemY_N PF07219.8 GAM19079.1 - 7.6 6.1 6.1 26 4.4 0.0 2.1 2 0 0 2 2 2 0 HemY protein N-terminus SMC_Nse1 PF07574.8 GAM19080.1 - 1.1e-20 74.1 4.6 1.6e-16 60.5 2.6 2.2 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex Cytochrom_C550 PF14495.1 GAM19080.1 - 0.0046 16.4 0.4 0.015 14.7 0.2 1.9 1 1 0 1 1 1 1 Cytochrome c-550 domain zf-rbx1 PF12678.2 GAM19080.1 - 0.02 14.9 4.5 0.046 13.8 3.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Erf4 PF10256.4 GAM19080.1 - 0.032 14.1 0.4 0.065 13.1 0.3 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family zf-RING-like PF08746.6 GAM19080.1 - 0.033 14.1 10.4 0.033 14.1 7.2 2.5 3 0 0 3 3 3 0 RING-like domain RraB PF06877.6 GAM19080.1 - 0.097 13.3 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B zf-RING_2 PF13639.1 GAM19080.1 - 0.18 11.6 13.5 0.12 12.1 7.1 2.4 3 0 0 3 3 3 0 Ring finger domain Mgr1 PF08602.5 GAM19080.1 - 0.18 10.7 2.0 0.25 10.3 1.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit zf-RING_4 PF14570.1 GAM19080.1 - 1 9.0 5.6 3 7.4 3.9 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 GAM19080.1 - 5.1 6.8 10.0 15 5.3 6.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COPI_assoc PF08507.5 GAM19081.1 - 2.5e-06 27.1 4.8 4.6e-06 26.3 3.3 1.4 1 0 0 1 1 1 1 COPI associated protein DUF308 PF03729.8 GAM19081.1 - 0.028 14.4 8.9 0.43 10.6 1.4 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF2142 PF09913.4 GAM19081.1 - 0.42 9.2 9.3 0.022 13.4 2.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) Dicty_CAR PF05462.6 GAM19082.1 - 7e-12 44.8 22.0 1.2e-11 44.0 15.3 1.3 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM19082.1 - 3.5e-10 39.3 19.1 5.3e-10 38.7 13.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 GAM19082.1 - 0.00042 19.5 21.4 0.0015 17.7 14.8 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.12 GAM19082.1 - 0.00064 18.6 20.6 0.006 15.4 7.5 2.5 2 1 1 3 3 3 2 Frizzled/Smoothened family membrane region Git3_C PF11970.3 GAM19082.1 - 0.0088 15.7 0.7 0.0088 15.7 0.5 2.5 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1681 PF07933.9 GAM19083.1 - 3.5e-57 192.4 0.0 3.5e-57 192.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) zf-C4H2 PF10146.4 GAM19083.1 - 0.23 11.4 4.2 0.33 10.9 2.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein PIG-F PF06699.6 GAM19084.1 - 5.4e-44 150.4 10.2 6.6e-44 150.1 7.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F RNase_T PF00929.19 GAM19085.1 - 1.8e-24 86.8 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Inhibitor_I69 PF13734.1 GAM19085.1 - 0.059 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Spi protease inhibitor Utp14 PF04615.8 GAM19087.1 - 3.8 5.5 39.1 0.39 8.8 24.1 1.5 2 0 0 2 2 2 0 Utp14 protein Hydrolase_3 PF08282.7 GAM19088.1 - 7.2e-60 202.6 0.1 8.4e-60 202.4 0.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 GAM19088.1 - 7.1e-09 35.3 0.0 0.00045 19.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 GAM19088.1 - 4.3e-06 27.3 0.0 1.6e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM19088.1 - 7.2e-05 23.0 0.2 0.075 13.1 0.0 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 GAM19088.1 - 0.053 13.4 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 GAM19089.1 - 3.7e-28 96.3 12.3 6.7e-07 28.9 0.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-C3HC4_4 PF15227.1 GAM19089.1 - 2.9e-05 23.8 1.2 7.3e-05 22.5 0.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 GAM19089.1 - 3.5e-05 23.7 1.9 0.0001 22.2 1.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM19089.1 - 9.6e-05 21.9 2.7 0.00033 20.2 1.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 GAM19089.1 - 0.0052 16.2 5.9 0.06 12.8 1.3 2.4 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-C3HC4_3 PF13920.1 GAM19089.1 - 0.009 15.6 1.3 0.016 14.9 0.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM19089.1 - 0.012 15.3 1.5 0.035 13.9 1.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 GAM19089.1 - 0.042 13.5 1.2 0.12 12.1 0.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 GAM19089.1 - 1.4 8.6 7.3 0.2 11.4 2.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain IncA PF04156.9 GAM19089.1 - 7.9 6.0 15.8 13 5.2 11.0 1.3 1 0 0 1 1 1 0 IncA protein SET PF00856.23 GAM19090.1 - 6.7e-09 36.2 3.3 3e-08 34.1 0.4 2.6 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 GAM19090.1 - 3.4e-05 23.6 7.1 3.4e-05 23.6 4.9 2.4 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 GAM19090.1 - 0.0081 15.4 2.8 0.038 13.2 1.2 2.5 2 0 0 2 2 2 1 Life-span regulatory factor NGF PF00243.13 GAM19090.1 - 0.24 11.1 4.3 1.5 8.5 0.2 3.4 4 1 0 4 4 4 0 Nerve growth factor family DUF1162 PF06650.7 GAM19091.1 - 4e-48 164.0 1.1 7.9e-43 146.6 0.0 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM19091.1 - 1.7e-29 101.7 0.1 1.7e-29 101.7 0.0 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAM19091.1 - 2e-07 31.0 0.0 7.2e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Peptidase_C1 PF00112.18 GAM19093.1 - 1.2e-45 156.0 0.2 2.2e-45 155.2 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.21 GAM19093.1 - 6.8e-09 36.2 1.4 6.8e-09 36.2 1.0 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family LSM PF01423.17 GAM19094.1 - 1.6e-13 50.0 0.2 2.2e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM19094.1 - 0.0012 18.6 0.0 0.0016 18.3 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF1256 PF06866.6 GAM19094.1 - 0.091 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) AAA_2 PF07724.9 GAM19096.1 - 1.7e-40 138.7 0.1 7.5e-32 110.5 0.1 2.9 2 1 1 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAM19096.1 - 1.3e-13 51.2 0.0 2.3e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 GAM19096.1 - 3.7e-09 36.3 1.2 1.7e-08 34.2 0.1 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 GAM19096.1 - 3.2e-06 26.9 0.1 0.00018 21.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM19096.1 - 6e-05 23.8 0.1 0.00019 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 GAM19096.1 - 6.6e-05 22.1 0.0 0.0034 16.5 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 GAM19096.1 - 0.00013 22.0 1.9 0.0044 17.1 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 GAM19096.1 - 0.00013 21.8 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM19096.1 - 0.00016 21.7 0.0 0.00042 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 GAM19096.1 - 0.00075 19.0 0.0 0.042 13.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 GAM19096.1 - 0.001 19.3 0.3 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAM19096.1 - 0.0043 16.7 0.0 0.0089 15.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 GAM19096.1 - 0.0058 15.7 0.0 0.052 12.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 GAM19096.1 - 0.0097 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MCM PF00493.18 GAM19096.1 - 0.011 14.5 0.1 0.089 11.5 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family IstB_IS21 PF01695.12 GAM19096.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.17 GAM19096.1 - 0.025 14.0 0.4 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SKI PF01202.17 GAM19096.1 - 0.04 13.7 0.3 0.7 9.7 0.2 2.6 1 1 0 1 1 1 0 Shikimate kinase AAA_33 PF13671.1 GAM19096.1 - 0.077 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF781 PF05612.7 GAM19097.1 - 2.4e-78 263.3 0.7 3.1e-78 262.9 0.5 1.0 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) Myb_DNA-binding PF00249.26 GAM19098.1 - 2.9e-10 40.0 0.1 5.6e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM19098.1 - 5.1e-05 23.2 0.1 0.00015 21.8 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1777 PF08648.7 GAM19098.1 - 0.093 12.4 62.8 0.013 15.1 16.3 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1777) DUF3452 PF11934.3 GAM19098.1 - 0.094 12.0 0.2 0.19 11.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Peptidase_C1 PF00112.18 GAM19099.1 - 1.7e-53 181.7 2.9 2.8e-53 181.0 2.0 1.3 1 1 0 1 1 1 1 Papain family cysteine protease Kelch_4 PF13418.1 GAM19100.1 - 8.6e-13 47.8 0.2 9.4e-06 25.3 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM19100.1 - 5.5e-11 42.1 8.4 0.014 15.5 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 GAM19100.1 - 1.5e-07 31.3 1.9 0.1 12.8 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM19100.1 - 9.5e-06 25.1 2.6 0.024 14.3 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 GAM19100.1 - 5.1e-05 22.7 7.3 0.013 15.0 0.0 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM19100.1 - 0.0055 16.6 4.2 1.4 8.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif FNIP PF05725.7 GAM19101.1 - 3.2e-27 94.2 28.2 2.1e-14 53.1 0.5 8.5 6 2 3 9 9 9 4 FNIP Repeat DUF1769 PF08588.5 GAM19101.1 - 0.16 11.9 1.1 13 5.7 0.0 3.9 2 2 3 5 5 5 0 Protein of unknown function (DUF1769) CS PF04969.11 GAM19102.1 - 2.8e-09 37.4 0.0 4.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 CS domain LIM_bind PF01803.11 GAM19102.1 - 0.055 12.5 0.2 0.058 12.4 0.1 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Protocadherin PF08374.6 GAM19103.1 - 0.051 13.1 0.2 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 Protocadherin Bacteriocin_IIc PF10439.4 GAM19103.1 - 0.057 13.5 0.4 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Podoplanin PF05808.6 GAM19103.1 - 0.14 11.7 2.9 0.24 10.9 2.0 1.4 1 0 0 1 1 1 0 Podoplanin Beta_helix PF13229.1 GAM19103.1 - 0.14 11.9 25.0 1.4 8.6 16.6 2.4 1 1 0 1 1 1 0 Right handed beta helix region Syndecan PF01034.15 GAM19103.1 - 0.17 11.5 2.6 0.37 10.4 1.8 1.5 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.8 GAM19103.1 - 0.19 11.2 1.5 0.4 10.1 1.1 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) LRR_8 PF13855.1 GAM19104.1 - 3.1e-19 68.4 72.6 7.2e-08 32.0 5.9 4.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 GAM19104.1 - 3.5e-18 64.7 40.1 2.7e-07 30.0 3.4 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM19104.1 - 7.7e-08 31.3 40.3 0.21 11.7 0.2 8.2 6 2 2 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.1 GAM19104.1 - 3.9e-06 26.3 33.6 0.051 13.6 0.6 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_7 PF13504.1 GAM19104.1 - 5.8e-06 25.6 32.0 0.65 10.4 0.3 8.2 8 0 0 8 8 8 4 Leucine rich repeat LRR_9 PF14580.1 GAM19104.1 - 0.00058 19.4 6.3 0.063 12.8 0.2 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_3 PF07725.7 GAM19104.1 - 0.012 15.2 8.7 2.1 8.2 0.5 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Peptidase_S9 PF00326.16 GAM19105.1 - 7.2e-47 159.3 0.0 2.2e-46 157.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 GAM19105.1 - 2e-30 105.6 4.3 3.4e-30 104.9 3.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 GAM19105.1 - 0.014 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PD40 PF07676.7 GAM19105.1 - 0.081 12.6 0.8 0.27 10.9 0.2 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HSP20 PF00011.16 GAM19106.1 - 2.3e-24 85.1 0.5 2.8e-24 84.9 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 GAM19106.1 - 0.075 12.5 0.1 0.099 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Myotub-related PF06602.9 GAM19107.1 - 1.2e-53 182.1 0.0 7.2e-53 179.5 0.0 2.3 2 1 0 2 2 2 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.12 GAM19107.1 - 1.2e-49 168.7 0.0 2.1e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM19107.1 - 2.6e-44 151.3 0.0 6.6e-44 149.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 GAM19107.1 - 3.6e-43 144.5 51.1 2.2e-09 36.7 0.5 9.5 7 2 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM19107.1 - 5e-28 96.6 48.2 1.3e-07 31.2 2.8 7.0 2 1 8 10 10 10 10 Leucine rich repeat RhoGAP PF00620.22 GAM19107.1 - 5.9e-18 64.9 0.0 1.6e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LRR_1 PF00560.28 GAM19107.1 - 1.7e-16 57.7 55.8 0.061 13.3 0.3 13.7 13 0 0 13 13 13 8 Leucine Rich Repeat LRR_9 PF14580.1 GAM19107.1 - 1.3e-06 28.0 11.5 3.1e-05 23.6 0.4 3.7 2 1 1 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 GAM19107.1 - 2.4e-06 26.8 47.6 1.7 9.2 0.1 13.0 12 1 1 13 13 13 3 Leucine rich repeat APH PF01636.18 GAM19107.1 - 0.24 11.1 0.0 0.46 10.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CorA PF01544.13 GAM19108.1 - 4.4e-59 199.9 6.4 5.3e-59 199.6 4.5 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein VIT1 PF01988.14 GAM19108.1 - 0.076 12.4 0.5 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 VIT family Tyrosinase PF00264.15 GAM19110.1 - 2.7e-41 142.1 1.3 3.7e-41 141.7 0.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BTG PF07742.7 GAM19110.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 BTG family TCTP PF00838.12 GAM19112.1 - 8.1e-45 152.7 3.1 9.4e-45 152.5 2.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein E1-E2_ATPase PF00122.15 GAM19113.1 - 2.3e-61 206.7 2.6 2.3e-61 206.7 1.8 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM19113.1 - 6.7e-25 88.7 0.0 1.2e-24 87.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM19113.1 - 7.4e-13 49.0 0.0 1.7e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM19113.1 - 1.2e-12 47.0 0.1 5.3e-12 45.0 0.0 2.2 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM19113.1 - 0.00019 21.0 0.2 0.0011 18.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 GAM19113.1 - 0.001 18.6 0.4 0.001 18.6 0.3 3.0 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 GAM19113.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit CDO_I PF05995.7 GAM19117.1 - 1.8e-24 85.8 0.1 2.8e-24 85.2 0.1 1.3 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 GAM19117.1 - 0.0059 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Actin PF00022.14 GAM19120.1 - 7e-163 541.6 0.0 7.9e-163 541.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM19120.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HAD_2 PF13419.1 GAM19121.1 - 5.6e-14 52.7 0.3 7.1e-14 52.4 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DnaJ PF00226.26 GAM19122.1 - 5.6e-24 83.6 1.3 9.5e-24 82.9 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 GAM19122.1 - 5.1e-05 23.4 0.1 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 GAM19122.1 - 0.038 13.8 0.1 5.3 7.2 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF605 PF04652.11 GAM19122.1 - 0.26 10.6 12.1 0.45 9.8 8.4 1.3 1 0 0 1 1 1 0 Vta1 like DUF2413 PF10310.4 GAM19122.1 - 0.48 9.1 5.5 0.65 8.7 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RAP1 PF07218.6 GAM19122.1 - 1.6 6.7 6.7 2.1 6.3 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAF-1_p150 PF11600.3 GAM19122.1 - 2.4 7.4 7.7 4.8 6.4 5.4 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ELFV_dehydrog PF00208.16 GAM19123.1 - 2.1e-57 194.5 0.4 3.8e-55 187.1 0.0 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 GAM19123.1 - 2.7e-44 149.9 0.0 4.4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.16 GAM19123.1 - 0.00037 20.3 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 GAM19123.1 - 0.0013 18.9 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 GAM19123.1 - 0.0016 18.0 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Bac_GDH PF05088.7 GAM19123.1 - 0.002 15.6 0.0 0.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase 2-Hacid_dh_C PF02826.14 GAM19123.1 - 0.0027 16.9 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phosphodiest PF01663.17 GAM19124.1 - 6.1e-66 223.2 1.6 2.2e-65 221.3 1.1 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM19124.1 - 4.6e-06 26.0 0.7 2e-05 23.9 0.0 2.3 2 1 1 3 3 3 1 Sulfatase Afaf PF15339.1 GAM19124.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF1501 PF07394.7 GAM19124.1 - 0.019 13.8 0.2 0.034 12.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) Metalloenzyme PF01676.13 GAM19124.1 - 0.021 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily TMEM51 PF15345.1 GAM19124.1 - 0.4 10.3 1.5 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 FNIP PF05725.7 GAM19125.1 - 3.9e-63 209.1 32.3 2.4e-13 49.7 0.5 7.9 6 2 1 8 8 8 7 FNIP Repeat Ank_2 PF12796.2 GAM19126.1 - 2.1e-08 34.3 7.9 0.067 13.5 0.0 7.2 6 3 2 8 8 8 4 Ankyrin repeats (3 copies) FNIP PF05725.7 GAM19127.1 - 2.8e-16 59.1 11.4 0.00024 20.9 0.1 6.2 5 1 1 6 6 6 4 FNIP Repeat Ank_2 PF12796.2 GAM19128.1 - 1.6e-06 28.3 0.3 1.2 9.5 0.1 5.5 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19128.1 - 0.00061 19.7 5.2 1.2e+02 3.4 0.0 6.9 6 1 1 7 7 7 0 Ankyrin repeat HHA PF05321.6 GAM19128.1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Haemolysin expression modulating protein Ank_2 PF12796.2 GAM19129.1 - 1.4e-07 31.7 0.7 0.07 13.4 0.0 4.6 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM19129.1 - 0.0011 19.0 0.5 11 6.3 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19129.1 - 0.01 15.9 0.7 1.5e+02 3.1 0.1 5.9 6 0 0 6 6 6 0 Ankyrin repeat HTH_10 PF04967.7 GAM19129.1 - 0.085 12.4 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain Pico_P1A PF02226.11 GAM19130.1 - 0.076 12.7 1.4 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 Picornavirus coat protein (VP4) FKBP_C PF00254.23 GAM19131.1 - 1.5e-18 66.6 0.0 2.5e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 GAM19131.1 - 2.8e-14 52.4 4.9 3.5e-07 29.7 1.2 2.5 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM19131.1 - 1.7e-09 36.8 6.4 7.5e-07 28.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM19131.1 - 2.4e-07 30.1 3.8 8.5e-07 28.4 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM19131.1 - 1.7e-05 24.6 1.1 0.002 18.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM19131.1 - 0.00013 21.7 1.6 0.00027 20.8 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM19131.1 - 0.00023 20.7 4.2 0.00028 20.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM19131.1 - 0.0082 16.2 1.8 0.03 14.4 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAM19131.1 - 0.0099 16.4 0.0 0.036 14.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM19131.1 - 0.031 14.7 2.1 0.11 12.9 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM19131.1 - 0.039 14.2 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAM19131.1 - 0.046 12.7 0.4 0.18 10.8 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat Vps55 PF04133.9 GAM19132.1 - 2.6e-31 107.8 4.0 3e-31 107.6 2.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 FNIP PF05725.7 GAM19133.1 - 1.5e-10 40.8 11.4 0.0022 17.9 0.0 6.4 5 2 1 6 6 6 4 FNIP Repeat FNIP PF05725.7 GAM19134.1 - 1.5e-44 149.7 13.0 1.1e-10 41.2 0.0 6.8 5 2 1 6 6 6 6 FNIP Repeat DUF1769 PF08588.5 GAM19134.1 - 0.024 14.5 1.3 1.1 9.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1769) Med20 PF08612.6 GAM19135.1 - 2.1e-21 76.1 0.1 2.9e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex SET PF00856.23 GAM19136.1 - 1e-11 45.4 0.6 1.6e-09 38.3 0.0 3.1 2 1 0 2 2 2 1 SET domain Nop14 PF04147.7 GAM19136.1 - 1.3 6.8 18.8 1.8 6.3 13.0 1.3 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.2 GAM19137.1 - 8e-33 112.6 9.3 2.5e-09 37.3 0.0 5.6 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19137.1 - 1.9e-23 80.2 12.3 0.12 12.7 0.0 11.6 8 2 3 11 11 11 8 Ankyrin repeat Ank_4 PF13637.1 GAM19137.1 - 1.1e-21 76.7 14.4 0.00017 22.0 0.0 8.3 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19137.1 - 2.3e-19 68.9 13.5 0.016 15.4 0.0 10.5 3 2 8 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM19137.1 - 6.5e-18 63.5 15.5 0.031 14.0 0.1 10.5 10 1 1 11 11 11 5 Ankyrin repeat DUF3447 PF11929.3 GAM19137.1 - 3e-07 30.1 0.2 0.48 10.2 0.4 4.6 2 2 2 4 4 4 3 Domain of unknown function (DUF3447) DUF249 PF03158.8 GAM19137.1 - 0.0046 16.5 2.0 6.2 6.3 0.0 4.5 1 1 3 4 4 4 1 Multigene family 530 protein Xin PF08043.7 GAM19137.1 - 1.3 8.9 4.2 76 3.3 0.0 3.4 3 0 0 3 3 3 0 Xin repeat LRR_8 PF13855.1 GAM19138.1 - 0.047 13.4 2.0 1.9 8.3 0.0 4.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 GAM19138.1 - 0.064 12.9 0.0 0.9 9.2 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Peptidase_C1 PF00112.18 GAM19140.1 - 8.6e-18 65.0 0.1 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.1 GAM19140.1 - 2.3e-06 27.9 0.0 6.2e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C47 PF05543.8 GAM19140.1 - 0.004 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Staphopain peptidase C47 TerB PF05099.8 GAM19140.1 - 0.053 13.2 0.8 0.18 11.5 0.6 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TerB EF1_GNE PF00736.14 GAM19140.1 - 0.071 12.8 0.2 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain NAAA-beta PF15508.1 GAM19141.1 - 2.5e-05 24.5 0.0 6.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Rsbr_N PF08678.5 GAM19141.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Rsbr N terminal BACK PF07707.10 GAM19142.1 - 7.8e-11 41.7 0.9 4.1e-08 32.9 0.0 3.2 2 1 1 3 3 3 2 BTB And C-terminal Kelch BTB PF00651.26 GAM19142.1 - 5.9e-06 26.2 0.1 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.3 GAM19142.1 - 9.3e-05 21.7 0.3 0.00015 21.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Sad1_UNC PF07738.8 GAM19142.1 - 0.00073 19.3 0.0 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal ACPS PF01648.15 GAM19143.1 - 1.2e-14 54.1 0.0 4.1e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily La PF05383.12 GAM19144.1 - 2.7e-24 84.7 0.4 5.7e-24 83.6 0.1 1.7 2 0 0 2 2 2 1 La domain RRM_3 PF08777.6 GAM19144.1 - 2.6e-22 78.6 3.0 1.7e-21 76.0 0.2 2.6 2 1 0 2 2 2 1 RNA binding motif RRM_6 PF14259.1 GAM19144.1 - 7.3e-14 51.4 0.1 1.4e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM19144.1 - 1.6e-10 40.4 2.4 1.8e-06 27.4 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19144.1 - 7.1e-08 32.1 0.5 0.0017 18.1 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EXS PF03124.9 GAM19145.1 - 8.1e-89 298.0 23.7 1.2e-88 297.5 16.5 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAM19145.1 - 1.6e-44 152.7 5.0 6.1e-42 144.2 5.0 2.1 2 0 0 2 2 2 2 SPX domain Kelch_6 PF13964.1 GAM19146.1 - 0.027 14.6 3.1 0.075 13.2 0.2 2.9 3 0 0 3 3 3 0 Kelch motif MKT1_N PF12247.3 GAM19146.1 - 0.13 12.6 0.5 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Kelch_6 PF13964.1 GAM19147.1 - 0.0039 17.3 3.4 0.086 13.0 0.0 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 GAM19148.1 - 0.047 13.8 1.1 1.2 9.3 0.0 2.9 2 1 0 2 2 2 0 Kelch motif zf-B_box PF00643.19 GAM19149.1 - 0.0062 16.4 6.7 0.02 14.7 4.6 1.9 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.1 GAM19149.1 - 0.15 12.0 6.6 23 5.0 0.2 4.3 3 1 0 3 3 3 0 Kelch motif PIN_4 PF13638.1 GAM19149.1 - 0.43 10.6 6.6 1.3 9.1 4.6 1.7 1 1 0 1 1 1 0 PIN domain AF0941-like PF14591.1 GAM19149.1 - 0.64 10.0 4.5 2 8.4 3.1 1.8 1 1 0 1 1 1 0 AF0941-like IncA PF04156.9 GAM19149.1 - 0.7 9.4 6.1 1.4 8.4 4.2 1.5 1 1 0 1 1 1 0 IncA protein Kelch_6 PF13964.1 GAM19149.1 - 0.94 9.7 3.9 4.3 7.6 0.1 3.9 3 1 1 4 4 4 0 Kelch motif zf-B_box PF00643.19 GAM19150.1 - 8.6e-08 31.9 4.8 8.6e-08 31.9 3.3 2.1 2 0 0 2 2 2 1 B-box zinc finger Fer2 PF00111.22 GAM19150.1 - 0.015 15.0 2.5 1.2 8.9 0.0 2.7 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain AF0941-like PF14591.1 GAM19150.1 - 0.82 9.7 5.1 2.6 8.1 3.1 2.1 2 1 0 2 2 2 0 AF0941-like zf-B_box PF00643.19 GAM19152.1 - 0.00057 19.7 6.9 0.0012 18.6 4.8 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.1 GAM19152.1 - 0.013 15.6 0.4 4.3 7.6 0.0 3.2 3 0 0 3 3 3 0 Kelch motif FNIP PF05725.7 GAM19153.1 - 2.2e-66 219.5 8.7 1.8e-13 50.1 0.1 8.6 5 2 5 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 GAM19153.1 - 1.2e-05 25.1 5.3 4.9 7.1 0.0 5.9 1 1 4 5 5 5 3 Protein of unknown function (DUF1769) F-box-like PF12937.2 GAM19153.1 - 0.00027 20.6 0.4 0.00057 19.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM19153.1 - 0.0011 18.5 0.6 0.0024 17.4 0.4 1.5 1 0 0 1 1 1 1 F-box domain adh_short PF00106.20 GAM19154.1 - 2.8e-27 95.6 0.0 3.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM19154.1 - 7.9e-12 45.4 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM19154.1 - 9.4e-09 35.1 0.1 0.00032 20.4 0.0 2.0 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 GAM19154.1 - 0.00085 19.3 0.1 0.058 13.4 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM19154.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 GAM19154.1 - 0.07 12.1 0.1 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA-synt_1c PF00749.16 GAM19155.1 - 5.9e-95 317.5 0.7 8.5e-95 317.0 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAM19155.1 - 9.4e-34 116.5 0.2 4.7e-33 114.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 GAM19155.1 - 7.8e-05 23.0 0.1 0.00021 21.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM19155.1 - 0.0099 15.8 0.1 0.032 14.1 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF87 PF01935.12 GAM19155.1 - 0.19 11.5 1.5 0.36 10.5 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 Ufm1 PF03671.9 GAM19156.1 - 2e-45 152.4 0.1 2.2e-45 152.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Rad60-SLD PF11976.3 GAM19156.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4206 PF13901.1 GAM19157.1 - 1.6e-60 204.1 17.5 1.6e-60 204.1 12.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4206) RUN PF02759.14 GAM19157.1 - 1.7e-26 92.5 2.7 4.6e-19 68.4 0.0 3.2 2 1 0 2 2 2 2 RUN domain Zn-ribbon_8 PF09723.5 GAM19157.1 - 1.6 8.7 15.7 1.3 9.0 0.0 4.7 4 1 1 5 5 5 0 Zinc ribbon domain DnaJ_CXXCXGXG PF00684.14 GAM19157.1 - 2.4 8.2 18.7 5.7 7.0 9.1 2.9 2 1 0 2 2 2 0 DnaJ central domain Prok-RING_1 PF14446.1 GAM19157.1 - 2.8 7.7 14.1 0.54 10.0 5.0 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_pol_B PF00136.16 GAM19158.1 - 9.9e-135 449.8 0.2 1.4e-134 449.3 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAM19158.1 - 2.2e-82 276.5 0.3 4.7e-82 275.4 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAM19158.1 - 2e-20 72.5 14.6 4.2e-20 71.5 10.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 GAM19158.1 - 0.00098 18.9 0.2 0.0034 17.2 0.2 1.9 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 GAM19158.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Nop14 PF04147.7 GAM19158.1 - 1.9 6.3 12.7 2.8 5.7 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM19158.1 - 4.2 5.7 14.0 33 2.7 9.4 2.1 2 0 0 2 2 2 0 Daxx Family BUD22 PF09073.5 GAM19158.1 - 4.2 6.3 10.0 6.7 5.6 6.9 1.2 1 0 0 1 1 1 0 BUD22 UQ_con PF00179.21 GAM19159.1 - 4.9e-30 103.7 0.0 7e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.7 GAM19159.1 - 0.016 14.2 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) DUF349 PF03993.7 GAM19160.1 - 0.0036 17.4 8.7 0.0057 16.7 6.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) PEARLI-4 PF05278.7 GAM19160.1 - 0.022 14.1 2.3 0.024 13.9 1.6 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) I_LWEQ PF01608.12 GAM19160.1 - 0.056 13.3 14.4 0.069 13.0 10.0 1.1 1 0 0 1 1 1 0 I/LWEQ domain Exonuc_VII_L PF02601.10 GAM19160.1 - 0.14 11.3 19.2 0.15 11.2 13.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uds1 PF15456.1 GAM19160.1 - 0.14 12.1 14.7 0.2 11.6 10.2 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Tweety PF04906.8 GAM19160.1 - 0.32 9.3 9.9 0.37 9.1 6.9 1.1 1 0 0 1 1 1 0 Tweety NAP PF00956.13 GAM19160.1 - 0.44 9.6 12.7 0.56 9.2 8.8 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) RTBV_P46 PF06216.6 GAM19160.1 - 0.55 9.0 5.5 0.62 8.8 3.8 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Cast PF10174.4 GAM19160.1 - 0.63 8.0 27.3 0.68 7.9 18.9 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone FemAB PF02388.11 GAM19160.1 - 0.67 8.5 13.8 0.72 8.4 9.5 1.1 1 0 0 1 1 1 0 FemAB family HemX PF04375.9 GAM19160.1 - 0.77 8.2 26.7 0.87 8.1 18.5 1.1 1 0 0 1 1 1 0 HemX DUF2365 PF10157.4 GAM19160.1 - 0.92 9.3 6.3 1.3 8.8 4.4 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Atg14 PF10186.4 GAM19160.1 - 1.4 7.7 23.1 1.5 7.6 16.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GBP_C PF02841.9 GAM19160.1 - 1.5 7.9 20.4 2 7.4 14.2 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain IFT57 PF10498.4 GAM19160.1 - 1.6 7.3 20.3 1.8 7.1 14.1 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 GAM19160.1 - 1.7 7.2 18.8 2 6.9 13.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 GAM19160.1 - 2.4 8.3 16.4 3.7 7.7 11.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.6 GAM19160.1 - 3.7 6.7 9.6 4.6 6.4 6.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein V_ATPase_I PF01496.14 GAM19160.1 - 3.8 5.2 13.7 3.8 5.2 9.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF745 PF05335.8 GAM19160.1 - 3.9 6.9 19.8 4.5 6.7 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF1664 PF07889.7 GAM19160.1 - 4.3 7.1 15.2 8.7 6.1 10.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.6 GAM19160.1 - 4.9 6.3 13.6 5.5 6.1 9.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.5 GAM19160.1 - 5 7.2 25.2 11 6.1 17.5 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DDE_Tnp_IS66 PF03050.9 GAM19160.1 - 5.3 6.1 12.4 6.3 5.9 8.6 1.0 1 0 0 1 1 1 0 Transposase IS66 family TMPIT PF07851.8 GAM19160.1 - 5.5 5.9 14.5 5.8 5.8 10.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Pex14_N PF04695.8 GAM19160.1 - 5.6 7.0 11.3 6.7 6.7 7.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Muted PF14942.1 GAM19160.1 - 5.7 6.8 19.6 6.4 6.6 13.6 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein OEP PF02321.13 GAM19160.1 - 5.7 6.4 25.8 8.3 5.9 17.9 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DOR PF14839.1 GAM19160.1 - 6.1 6.5 13.2 8 6.1 9.2 1.2 1 0 0 1 1 1 0 DOR family DUF501 PF04417.7 GAM19160.1 - 6.6 6.5 9.4 7.8 6.3 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF501) DUF763 PF05559.6 GAM19160.1 - 6.6 5.5 7.4 7.1 5.4 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Cob_adeno_trans PF01923.13 GAM19160.1 - 8 6.2 13.5 18 5.1 9.3 1.5 1 1 0 1 1 1 0 Cobalamin adenosyltransferase SID-1_RNA_chan PF13965.1 GAM19160.1 - 8.6 4.3 6.8 9.6 4.2 4.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Prominin PF05478.6 GAM19160.1 - 8.9 3.6 16.4 9.9 3.5 11.3 1.1 1 0 0 1 1 1 0 Prominin Tho2 PF11262.3 GAM19160.1 - 9.4 5.1 10.7 11 4.9 7.4 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 EMP24_GP25L PF01105.19 GAM19160.1 - 9.5 5.8 12.6 12 5.5 8.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Peptidase_U57 PF05582.7 GAM19160.1 - 9.7 5.0 10.0 11 4.9 6.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Abhydrolase_6 PF12697.2 GAM19161.1 - 4.7e-35 121.5 0.1 6.2e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM19161.1 - 1e-17 64.5 0.1 1e-17 64.5 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM19161.1 - 2.9e-14 53.0 0.0 9.4e-14 51.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 GAM19161.1 - 0.00076 18.0 0.0 0.0016 17.0 0.0 1.4 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 GAM19161.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 GAM19161.1 - 0.0024 18.1 0.1 0.0065 16.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.15 GAM19161.1 - 0.0064 15.9 0.2 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 Putative esterase Mem_trans PF03547.13 GAM19161.1 - 0.12 10.6 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein UPF0182 PF03699.8 GAM19161.1 - 0.16 9.8 3.3 0.22 9.4 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4175 PF13779.1 GAM19161.1 - 2.7 5.6 12.6 3.4 5.2 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GATA PF00320.22 GAM19162.1 - 6.4e-16 57.4 5.6 6.4e-16 57.4 3.9 2.0 2 0 0 2 2 2 1 GATA zinc finger BSP_II PF05432.6 GAM19162.1 - 0.0002 20.7 6.8 0.0002 20.7 4.7 2.2 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 GAM19162.1 - 0.0057 15.9 6.8 0.0057 15.9 4.7 2.1 2 0 0 2 2 2 1 NOA36 protein Nop14 PF04147.7 GAM19162.1 - 0.22 9.3 15.9 0.038 11.9 7.4 2.1 2 0 0 2 2 2 0 Nop14-like family Nucleoplasmin PF03066.10 GAM19162.1 - 0.29 10.6 8.8 0.61 9.6 6.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin Macro PF01661.16 GAM19164.1 - 9.4e-29 99.7 0.1 2.7e-28 98.2 0.1 1.9 1 0 0 1 1 1 1 Macro domain PARP PF00644.15 GAM19164.1 - 2.2e-21 76.2 2.5 1.3e-20 73.6 1.8 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 GAM19164.1 - 6.7e-05 22.2 0.7 0.00043 19.6 0.5 2.5 1 0 0 1 1 1 1 WWE domain Ank_2 PF12796.2 GAM19166.1 - 1.6e-06 28.3 0.0 0.0068 16.7 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19167.1 - 0.0024 17.9 1.1 14 6.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 GAM19167.1 - 0.003 17.8 0.4 0.017 15.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM19168.1 - 3.3e-17 62.5 7.8 0.04 14.2 0.0 9.0 6 3 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19168.1 - 9.5e-07 28.4 24.7 22 5.6 0.0 14.3 17 0 0 17 17 17 1 Ankyrin repeat Ank_4 PF13637.1 GAM19168.1 - 2.7e-06 27.7 10.7 0.55 10.8 0.1 8.7 10 1 1 11 11 11 2 Ankyrin repeats (many copies) Alpha_kinase PF02816.13 GAM19169.1 - 2.6e-61 206.5 0.1 2.6e-61 206.5 0.0 2.0 2 0 0 2 2 2 1 Alpha-kinase family WD40 PF00400.27 GAM19169.1 - 7.7e-43 142.8 22.6 5.7e-09 35.5 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 GAM19169.1 - 0.037 14.2 0.1 6.3 7.2 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Baculo_PEP_C PF04513.7 GAM19169.1 - 2.1 8.1 24.0 0.013 15.2 2.3 4.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RabGAP-TBC PF00566.13 GAM19170.1 - 1.7e-49 168.2 0.7 4e-49 166.9 0.5 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 GAM19170.1 - 2e-41 140.2 7.7 1e-17 64.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM19170.1 - 2.2e-23 80.8 0.4 3.4e-06 26.5 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 GAM19170.1 - 4.6e-15 54.2 0.2 0.00063 19.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 GAM19170.1 - 6e-15 55.3 0.3 0.00013 22.3 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19170.1 - 2.9e-13 49.5 1.5 0.0025 17.9 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SHOCT PF09851.4 GAM19171.1 - 0.00018 20.8 0.2 0.00018 20.8 0.1 2.7 3 0 0 3 3 3 1 Short C-terminal domain Clathrin_lg_ch PF01086.12 GAM19171.1 - 0.0064 16.4 2.3 0.013 15.4 1.6 1.5 1 0 0 1 1 1 1 Clathrin light chain Pam16 PF03656.8 GAM19171.1 - 0.12 12.1 0.2 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Pam16 TIG PF01833.19 GAM19172.1 - 5.9e-08 32.5 43.9 0.0035 17.2 2.2 6.7 6 1 0 6 6 6 4 IPT/TIG domain EGF_2 PF07974.8 GAM19172.1 - 0.012 15.7 14.0 0.028 14.5 9.7 1.7 1 0 0 1 1 1 0 EGF-like domain PepSY_TM_2 PF13703.1 GAM19172.1 - 0.021 14.9 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix DUF1191 PF06697.7 GAM19172.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EB PF01683.13 GAM19172.1 - 0.12 12.4 7.3 0.31 11.1 5.1 1.6 1 0 0 1 1 1 0 EB module EGF PF00008.22 GAM19172.1 - 0.3 11.1 10.8 0.79 9.7 7.5 1.8 1 0 0 1 1 1 0 EGF-like domain Cna_B PF05738.8 GAM19173.1 - 3.5e-89 292.5 39.7 5.2e-07 29.3 0.1 15.9 15 0 0 15 15 15 15 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM19173.1 - 8.2e-77 253.3 31.9 4.1e-07 29.9 0.1 14.8 15 0 0 15 15 15 14 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 GAM19173.1 - 1.4e-24 86.3 0.1 0.00031 20.5 0.0 12.6 14 0 0 14 14 14 4 Protein of unknown function (DUF2012) FlgD_ig PF13860.1 GAM19173.1 - 9.1e-16 57.3 21.1 2.6 7.8 0.0 16.0 17 2 0 17 17 16 4 FlgD Ig-like domain DUF4480 PF13715.1 GAM19173.1 - 1e-14 54.3 22.1 0.4 10.7 0.0 13.5 14 0 0 14 14 14 3 Domain of unknown function (DUF4480) MG1 PF11974.3 GAM19173.1 - 2.2e-12 47.3 3.6 8.1 7.0 0.0 11.3 13 0 0 13 13 12 1 Alpha-2-macroglobulin MG1 domain Y_Y_Y PF07495.8 GAM19173.1 - 1.4e-10 40.7 24.2 1 9.1 0.0 13.1 14 0 0 14 14 14 2 Y_Y_Y domain fn3_3 PF14686.1 GAM19173.1 - 2.6e-10 40.2 29.6 15 5.7 0.2 14.2 14 0 0 14 14 14 0 Polysaccharide lyase family 4, domain II DUF2322 PF10084.4 GAM19173.1 - 4.5e-09 35.9 3.0 14 5.4 0.0 9.0 9 0 0 9 9 9 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF2141 PF09912.4 GAM19173.1 - 2.7e-07 30.2 9.8 1.4 8.5 0.1 11.3 14 0 0 14 14 14 1 Uncharacterized protein conserved in bacteria (DUF2141) DUF2846 PF11008.3 GAM19173.1 - 0.00043 20.1 1.8 3.3 7.5 0.0 6.9 9 0 0 9 9 8 1 Protein of unknown function (DUF2846) Borrelia_REV PF03978.8 GAM19173.1 - 0.00061 19.5 10.2 1.3 8.6 0.0 6.8 9 0 0 9 9 9 1 Borrelia burgdorferi REV protein DUF4019 PF13211.1 GAM19173.1 - 0.0013 18.9 0.3 27 5.0 0.0 6.7 8 0 0 8 8 7 0 Protein of unknown function (DUF4019) Glyco_hydro_4 PF02056.11 GAM19173.1 - 0.002 17.5 0.0 97 2.1 0.0 5.9 8 0 0 8 8 8 0 Family 4 glycosyl hydrolase NIF PF03031.13 GAM19175.1 - 2.8e-55 186.3 0.4 2.8e-55 186.3 0.3 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 GAM19175.1 - 0.098 12.8 0.3 1.4 9.0 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Xpo1 PF08389.7 GAM19177.1 - 2.8e-18 66.2 0.9 2.8e-18 66.2 0.6 6.8 5 2 1 6 6 6 1 Exportin 1-like protein DUF1722 PF08349.6 GAM19177.1 - 0.0079 16.0 0.3 0.0079 16.0 0.2 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1722) IBN_N PF03810.14 GAM19177.1 - 0.015 15.2 0.3 0.015 15.2 0.2 3.1 4 0 0 4 4 4 0 Importin-beta N-terminal domain TFCD_C PF12612.3 GAM19177.1 - 0.056 12.8 0.1 0.056 12.8 0.1 2.7 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Secretin_N_2 PF07655.8 GAM19177.1 - 0.46 10.9 21.3 1.6 9.1 14.8 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Mononeg_mRNAcap PF14318.1 GAM19177.1 - 2.8 6.9 14.1 0.53 9.2 6.7 2.0 2 0 0 2 2 2 0 Mononegavirales mRNA-capping region V Methyltransf_16 PF10294.4 GAM19178.1 - 5.3e-22 78.0 0.2 2.6e-19 69.3 0.1 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAM19178.1 - 1.7e-07 31.0 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM19178.1 - 0.00051 20.0 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM19178.1 - 0.00059 19.4 0.2 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM19178.1 - 0.00073 20.1 0.3 0.0085 16.6 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM19178.1 - 0.0029 18.0 0.0 0.011 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 GAM19178.1 - 0.0075 15.4 0.0 0.034 13.2 0.0 1.9 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G MTS PF05175.9 GAM19178.1 - 0.021 14.2 0.0 0.94 8.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 GAM19178.1 - 0.029 14.8 0.0 0.26 11.7 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF1702 PF08012.6 GAM19178.1 - 0.038 12.6 0.0 0.054 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) DUF3113 PF11310.3 GAM19178.1 - 0.094 12.4 0.5 0.26 11.0 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) NodS PF05401.6 GAM19178.1 - 0.15 11.4 0.1 1.1 8.6 0.1 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) OGG_N PF07934.7 GAM19179.1 - 3.1e-23 81.9 1.2 3.1e-23 81.9 0.9 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 GAM19179.1 - 4e-08 33.5 0.0 6.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RXT2_N PF08595.6 GAM19179.1 - 0.011 15.5 1.4 0.021 14.6 1.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 GAM19179.1 - 0.048 13.1 5.1 0.079 12.4 3.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin HHH PF00633.18 GAM19179.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Trypan_PARP PF05887.6 GAM19179.1 - 0.08 12.7 5.1 0.12 12.1 3.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.1 GAM19179.1 - 0.14 12.4 11.6 0.29 11.4 8.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 GAM19179.1 - 0.68 9.5 8.1 1.3 8.6 5.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 GAM19179.1 - 0.73 9.0 5.8 1.4 8.1 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 GAM19179.1 - 1.1 8.8 6.0 2.1 8.0 4.2 1.3 1 0 0 1 1 1 0 FAM176 family DUF2151 PF10221.4 GAM19179.1 - 1.4 7.0 6.4 2.4 6.2 4.4 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator BSP_II PF05432.6 GAM19179.1 - 4.1 6.5 14.5 0.038 13.2 4.7 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.5 GAM19179.1 - 4.5 7.5 10.6 9.2 6.5 7.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Vfa1 PF08432.5 GAM19179.1 - 5.9 6.8 10.0 13 5.7 6.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4229 PF14012.1 GAM19180.1 - 0.0072 16.2 0.6 0.012 15.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) Protocadherin PF08374.6 GAM19180.1 - 0.015 14.9 0.8 0.02 14.5 0.6 1.2 1 0 0 1 1 1 0 Protocadherin 7TM_GPCR_Srx PF10328.4 GAM19180.1 - 0.025 13.7 0.1 0.032 13.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx RskA PF10099.4 GAM19180.1 - 0.043 13.5 0.7 0.059 13.0 0.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Adeno_E3_CR2 PF02439.10 GAM19180.1 - 0.045 13.2 6.3 0.083 12.4 4.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 GAM19180.1 - 0.068 13.5 2.7 0.12 12.7 1.9 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 GAM19180.1 - 0.082 11.1 0.4 0.11 10.7 0.3 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 GAM19180.1 - 0.095 12.1 0.6 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF912 PF06024.7 GAM19180.1 - 0.13 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pentapeptide_4 PF13599.1 GAM19181.1 - 0.039 13.7 0.2 0.67 9.7 0.0 2.6 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Usp PF00582.21 GAM19182.1 - 8.2e-18 64.9 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family CoA_binding_3 PF13727.1 GAM19182.1 - 0.056 13.2 0.1 0.067 13.0 0.1 1.1 1 0 0 1 1 1 0 CoA-binding domain RRM_1 PF00076.17 GAM19183.1 - 5.9e-21 73.8 0.2 9.6e-21 73.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19183.1 - 5.6e-15 55.0 0.0 8.9e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19183.1 - 3e-08 33.3 0.0 4.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 GAM19183.1 - 7e-08 32.6 0.5 7e-08 32.6 0.3 2.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Nup35_RRM_2 PF14605.1 GAM19183.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif XS PF03468.9 GAM19183.1 - 0.11 12.3 0.7 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 XS domain MFS_1 PF07690.11 GAM19184.1 - 7.5e-24 84.0 49.3 4.4e-22 78.2 26.3 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily COX2_TM PF02790.10 GAM19184.1 - 3 7.8 11.9 0.26 11.2 0.3 3.9 4 0 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain Ank_3 PF13606.1 GAM19185.1 - 0.012 15.7 0.3 3.3 8.2 0.0 4.2 3 0 0 3 3 3 0 Ankyrin repeat Sec1 PF00995.18 GAM19187.1 - 4.4e-133 444.9 6.0 5e-133 444.7 4.1 1.0 1 0 0 1 1 1 1 Sec1 family Fcf1 PF04900.7 GAM19189.1 - 2.3e-38 130.3 1.6 2.3e-38 130.3 1.1 1.5 2 0 0 2 2 2 1 Fcf1 Peptidase_M20 PF01546.23 GAM19190.1 - 1.3e-26 93.3 0.0 1.8e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM19190.1 - 6.1e-08 32.3 0.0 1.3e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Ras PF00071.17 GAM19191.1 - 9.4e-61 203.9 0.7 1.6e-60 203.1 0.5 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19191.1 - 2.3e-20 73.2 0.3 5e-20 72.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM19191.1 - 1.3e-13 50.5 0.2 2.1e-13 49.9 0.1 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM19191.1 - 7e-08 32.4 0.3 1.4e-07 31.5 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM19191.1 - 1.4e-06 27.8 0.6 5.7e-06 25.8 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 GAM19191.1 - 5.5e-05 22.3 0.0 8.1e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 GAM19191.1 - 6.1e-05 22.2 0.6 8.5e-05 21.8 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAM19191.1 - 8.9e-05 22.6 0.3 0.00054 20.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.5 GAM19191.1 - 0.00012 21.4 0.1 0.00035 19.8 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 GAM19191.1 - 0.0034 16.5 0.8 0.0056 15.8 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 GAM19191.1 - 0.0045 16.8 0.2 0.014 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 GAM19191.1 - 0.012 14.9 0.9 0.099 11.9 0.2 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 GAM19191.1 - 0.019 14.9 0.4 0.041 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 GAM19191.1 - 0.032 14.5 0.9 0.065 13.5 0.6 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 GAM19191.1 - 0.04 13.4 0.2 0.21 11.0 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 GAM19191.1 - 0.085 12.8 0.3 0.61 10.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain YtzH PF14165.1 GAM19191.1 - 0.088 13.0 0.5 0.33 11.1 0.3 1.9 2 0 0 2 2 2 0 YtzH-like protein SpoIIID PF12116.3 GAM19191.1 - 0.092 12.6 1.1 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_29 PF13555.1 GAM19191.1 - 0.12 11.9 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 GAM19191.1 - 0.13 11.7 1.0 0.49 9.9 0.7 2.1 1 1 0 1 1 1 0 AAA domain Vps26 PF03643.10 GAM19192.1 - 4.9e-128 425.6 5.2 5.6e-128 425.4 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAM19192.1 - 0.0038 17.0 1.9 0.8 9.5 0.0 3.1 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain DUF4149 PF13664.1 GAM19193.1 - 1.2 9.2 13.5 5 7.2 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Ceramidase PF05875.7 GAM19195.1 - 8.3e-60 202.1 11.3 1.1e-59 201.7 7.8 1.1 1 0 0 1 1 1 1 Ceramidase Na_Ca_ex PF01699.19 GAM19195.1 - 2.5 7.7 11.9 7.2 6.2 1.0 2.9 1 1 2 3 3 3 0 Sodium/calcium exchanger protein Peptidase_M76 PF09768.4 GAM19196.1 - 7.8e-45 152.4 1.5 8.6e-45 152.2 1.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 GAM19196.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Tox-MPTase2 PF15638.1 GAM19196.1 - 0.071 12.6 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Ribonuc_red_lgC PF02867.10 GAM19197.1 - 4.7e-05 22.1 0.0 0.037 12.5 0.0 3.2 3 0 0 3 3 3 2 Ribonucleotide reductase, barrel domain Aminotran_3 PF00202.16 GAM19198.1 - 8.4e-106 353.6 0.0 1.1e-105 353.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Nanovirus_coat PF04660.7 GAM19198.1 - 0.085 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Nanovirus coat protein Ribosomal_L23 PF00276.15 GAM19199.1 - 3.9e-16 58.7 1.4 3.9e-16 58.7 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 GAM19199.1 - 2.6e-15 56.1 11.4 2.6e-15 56.1 7.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L18p PF00861.17 GAM19199.1 - 0.1 12.7 3.6 0.28 11.3 0.1 2.3 2 1 0 2 2 2 0 Ribosomal L18p/L5e family Ribosomal_L30_N PF08079.7 GAM19199.1 - 0.99 9.4 5.6 2.7 8.0 3.9 1.7 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain P2X_receptor PF00864.14 GAM19201.1 - 5.4e-20 71.4 0.4 1.2e-10 40.6 0.3 2.5 2 1 0 2 2 2 2 ATP P2X receptor DUF4202 PF13875.1 GAM19202.1 - 0.11 12.1 0.1 0.24 11.0 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4202) VirDNA-topo-I_N PF09266.5 GAM19202.1 - 0.15 11.9 1.4 0.19 11.6 0.4 1.6 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal Ribosomal_L32e PF01655.13 GAM19203.1 - 5e-43 145.6 0.4 6.1e-43 145.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 zf-MYND PF01753.13 GAM19204.1 - 1.5e-11 43.9 5.3 3.2e-11 42.8 3.6 1.6 1 0 0 1 1 1 1 MYND finger RhoGAP PF00620.22 GAM19206.1 - 1.3e-34 119.0 0.0 2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain GST_N PF02798.15 GAM19207.1 - 1.9e-13 50.3 0.0 3.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM19207.1 - 3.3e-08 33.4 0.1 5.3e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM19207.1 - 1.8e-05 24.5 0.1 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM19207.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM19207.1 - 3.5e-05 24.2 0.1 5.1e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1972 PF09314.6 GAM19207.1 - 0.0091 15.4 0.0 0.46 9.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1972) DUF3384 PF11864.3 GAM19208.1 - 7.8e-82 275.1 11.0 7.8e-82 275.1 7.6 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 GAM19208.1 - 1.3e-66 223.5 0.6 3.2e-66 222.3 0.4 1.7 1 0 0 1 1 1 1 Rap/ran-GAP OppC_N PF12911.2 GAM19209.1 - 0.18 11.1 0.0 0.18 11.1 0.0 3.9 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C WCOR413 PF05562.6 GAM19209.1 - 0.74 9.3 8.2 2.5 7.5 0.1 2.6 2 1 1 3 3 3 0 Cold acclimation protein WCOR413 MgtE PF01769.11 GAM19209.1 - 6.7 7.0 15.6 0.73 10.1 3.7 2.5 3 0 0 3 3 3 0 Divalent cation transporter NfeD PF01957.13 GAM19209.1 - 9.2 6.3 13.2 3.9 7.5 2.7 2.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding SnoaL_2 PF12680.2 GAM19210.1 - 0.0003 21.1 0.0 0.00037 20.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF3271 PF11675.3 GAM19210.1 - 0.0016 17.5 2.9 0.0019 17.3 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3271) SnoaL PF07366.7 GAM19210.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF4440 PF14534.1 GAM19210.1 - 0.038 14.2 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Brix PF04427.13 GAM19211.1 - 4e-35 121.2 0.5 7.5e-35 120.3 0.4 1.4 1 0 0 1 1 1 1 Brix domain SoxE PF06525.6 GAM19211.1 - 0.029 13.6 1.5 0.055 12.7 1.1 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) DUF3439 PF11921.3 GAM19211.1 - 0.12 12.1 5.4 0.17 11.6 3.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Cpn10 PF00166.16 GAM19212.1 - 5.9e-20 71.0 0.1 6.6e-20 70.8 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit LSM PF01423.17 GAM19213.1 - 7.9e-14 50.9 0.4 9.9e-14 50.6 0.3 1.1 1 0 0 1 1 1 1 LSM domain MKT1_C PF12246.3 GAM19214.1 - 3.4e-38 131.0 0.3 5.7e-38 130.2 0.2 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 GAM19214.1 - 2.9e-21 75.5 0.0 1.3e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 GAM19214.1 - 2.4e-09 37.1 0.0 6.3e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region DUF1897 PF09005.5 GAM19214.1 - 0.06 12.8 2.7 0.13 11.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) GMC_oxred_N PF00732.14 GAM19215.1 - 8.7e-43 146.5 0.0 1.4e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM19215.1 - 5e-24 85.2 1.3 8.7e-24 84.4 0.9 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM19215.1 - 0.00022 21.1 0.2 0.0012 18.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM19215.1 - 0.001 17.6 0.1 0.0015 17.0 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 GAM19215.1 - 0.0013 18.6 1.7 0.0036 17.2 1.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM19215.1 - 0.0013 18.1 0.1 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 GAM19215.1 - 0.0031 16.4 2.8 0.0061 15.4 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM19215.1 - 0.0058 16.7 0.1 0.2 11.6 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM19215.1 - 0.0076 15.2 0.5 0.012 14.6 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 GAM19215.1 - 0.028 13.3 5.6 0.021 13.7 2.2 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM19215.1 - 0.031 13.1 0.9 0.045 12.6 0.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 GAM19215.1 - 0.041 12.9 1.5 0.094 11.7 1.1 1.5 1 0 0 1 1 1 0 Thi4 family QRPTase_C PF01729.14 GAM19215.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain TrkA_N PF02254.13 GAM19215.1 - 0.17 11.9 2.8 0.12 12.3 0.5 1.9 3 0 0 3 3 2 0 TrkA-N domain FAD_binding_3 PF01494.14 GAM19215.1 - 0.24 10.4 2.0 0.4 9.6 1.4 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 GAM19215.1 - 0.67 8.5 2.1 3.1 6.3 2.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase ABC_tran PF00005.22 GAM19216.1 - 1.6e-25 89.9 0.0 2.5e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 GAM19216.1 - 1.2e-10 40.9 0.8 1.8e-10 40.3 0.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.1 GAM19216.1 - 6.1e-09 36.2 0.0 0.0018 18.3 0.1 2.2 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM19216.1 - 3.4e-05 23.2 0.1 7.3e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM19216.1 - 8.2e-05 23.4 0.0 0.00018 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM19216.1 - 0.00027 20.1 0.3 0.00081 18.6 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM19216.1 - 0.00027 20.9 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 GAM19216.1 - 0.00041 19.7 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM19216.1 - 0.00046 20.4 0.0 0.00092 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAM19216.1 - 0.00049 19.2 0.0 0.019 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 GAM19216.1 - 0.0012 18.1 0.0 0.028 13.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 GAM19216.1 - 0.0018 18.1 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM19216.1 - 0.0024 18.0 0.3 0.0071 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 GAM19216.1 - 0.0083 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 GAM19216.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 GAM19216.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM19216.1 - 0.025 14.3 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase SbcCD_C PF13558.1 GAM19216.1 - 0.037 13.9 0.2 0.32 10.9 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 GAM19216.1 - 0.038 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 GAM19216.1 - 0.053 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 GAM19216.1 - 0.057 13.7 0.1 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAM19216.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 GAM19216.1 - 0.082 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 GAM19216.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 GAM19216.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane PF01061.19 GAM19217.1 - 1e-23 83.6 12.9 1e-23 83.6 8.9 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 GAM19217.1 - 3.9e-05 22.8 16.6 5e-05 22.4 11.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Longin PF13774.1 GAM19218.1 - 1e-25 89.0 1.9 2e-25 88.1 1.3 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 GAM19218.1 - 2.5e-14 52.6 0.1 4.9e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin TPR_11 PF13414.1 GAM19219.1 - 1.6e-19 69.3 2.2 3.3e-15 55.4 0.5 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM19219.1 - 1.5e-15 56.0 2.9 4e-05 23.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM19219.1 - 8.7e-14 50.2 0.8 0.00045 19.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-RING_2 PF13639.1 GAM19219.1 - 2.6e-07 30.3 14.7 6.9e-07 29.0 10.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM19219.1 - 7.9e-07 28.6 15.6 2.1e-06 27.2 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 GAM19219.1 - 9.7e-07 28.1 3.5 0.017 14.8 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 GAM19219.1 - 1e-06 28.6 15.6 2.7e-06 27.2 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 GAM19219.1 - 1.3e-06 28.2 0.8 0.00018 21.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM19219.1 - 1.8e-06 27.6 1.0 0.071 13.3 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat zf-RING_5 PF14634.1 GAM19219.1 - 2.4e-06 27.1 15.1 6.1e-06 25.8 10.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Apc3 PF12895.2 GAM19219.1 - 2.7e-06 27.4 2.8 2.7e-06 27.4 2.0 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4_3 PF13920.1 GAM19219.1 - 7.5e-06 25.5 11.4 2e-05 24.1 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM19219.1 - 2.9e-05 23.8 16.5 6e-05 22.8 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING NARP1 PF12569.3 GAM19219.1 - 5e-05 22.2 0.2 7.4e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 GAM19219.1 - 5.1e-05 23.8 0.0 0.015 15.9 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-RING_6 PF14835.1 GAM19219.1 - 0.00045 19.9 6.8 0.00091 18.9 4.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 GAM19219.1 - 0.0018 17.9 6.0 0.0018 17.9 4.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger TPR_19 PF14559.1 GAM19219.1 - 0.002 18.4 0.0 0.084 13.2 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM19219.1 - 0.018 14.8 0.3 0.049 13.4 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_4 PF14570.1 GAM19219.1 - 0.34 10.5 16.8 0.13 11.8 9.4 2.0 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain TPR_6 PF13174.1 GAM19219.1 - 0.38 11.3 1.5 35 5.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Zip PF02535.17 GAM19219.1 - 0.74 8.7 9.5 1.2 8.1 6.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Baculo_IE-1 PF05290.6 GAM19219.1 - 3.6 7.3 10.4 3.2 7.4 4.8 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) PARP PF00644.15 GAM19220.1 - 6e-08 32.3 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 GAM19220.1 - 1.3e-07 30.9 0.2 2.8e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 WWE domain Vault PF01505.13 GAM19220.1 - 0.00038 20.4 0.0 0.00038 20.4 0.0 1.8 2 0 0 2 2 2 1 Major Vault Protein repeat RasGAP PF00616.14 GAM19221.1 - 1.1e-40 139.3 4.2 1.1e-40 139.3 2.9 2.5 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 GAM19221.1 - 7e-20 71.1 11.7 7e-20 71.1 8.1 3.6 2 2 1 3 3 3 1 RasGAP C-terminus PepSY_TM_2 PF13703.1 GAM19222.1 - 0.075 13.2 0.0 0.075 13.2 0.0 3.2 4 0 0 4 4 4 0 PepSY-associated TM helix PLAC8 PF04749.12 GAM19222.1 - 0.12 12.9 2.8 0.33 11.5 1.9 1.7 1 0 0 1 1 1 0 PLAC8 family Beta_helix PF13229.1 GAM19223.1 - 5.3e-40 136.7 66.4 2.9e-21 75.8 17.6 4.1 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.8 GAM19223.1 - 1.8e-29 102.5 52.4 2.4e-13 49.7 8.1 3.4 2 1 2 4 4 4 3 Periplasmic copper-binding protein (NosD) zf-UBR PF02207.15 GAM19223.1 - 1.2e-11 44.1 12.1 3e-11 42.8 8.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Pectate_lyase_3 PF12708.2 GAM19223.1 - 3.2e-08 33.9 29.0 6e-05 23.2 4.8 3.7 1 1 1 2 2 2 2 Pectate lyase superfamily protein F-box-like PF12937.2 GAM19223.1 - 1.4e-07 31.0 2.1 2.7e-07 30.2 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM19223.1 - 3.1e-06 26.7 2.6 5.5e-06 25.8 1.8 1.4 1 0 0 1 1 1 1 F-box domain BTB PF00651.26 GAM19224.1 - 2.7e-16 59.5 1.9 1.5e-13 50.6 0.2 2.6 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 GAM19224.1 - 6.2e-11 42.0 2.7 3.2e-08 33.3 0.2 3.2 3 0 0 3 3 3 2 BTB And C-terminal Kelch F5_F8_type_C PF00754.20 GAM19224.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.8 GAM19224.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PWWP PF00855.12 GAM19225.1 - 5.3e-13 48.9 0.8 5.3e-13 48.9 0.5 3.4 3 0 0 3 3 3 2 PWWP domain Acatn PF13000.2 GAM19226.1 - 4.2e-109 365.5 26.2 2.4e-88 297.0 7.6 2.3 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 ATP-synt_8 PF00895.15 GAM19226.1 - 4.1 7.6 13.9 13 6.1 0.5 4.7 4 1 0 4 4 4 0 ATP synthase protein 8 FNIP PF05725.7 GAM19227.1 - 8.9e-61 201.6 18.4 7.2e-13 48.2 0.0 9.3 8 2 0 9 9 9 7 FNIP Repeat DUF1769 PF08588.5 GAM19227.1 - 0.00052 19.9 0.3 3.2 7.7 0.1 5.0 4 1 1 5 5 5 2 Protein of unknown function (DUF1769) EXOSC1 PF10447.4 GAM19228.1 - 1e-25 89.4 0.9 2.8e-25 88.0 0.6 1.8 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 GAM19228.1 - 2.6e-16 58.6 0.1 6.1e-16 57.4 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CM_1 PF07736.6 GAM19228.1 - 0.0023 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Chorismate mutase type I DNA_pol_B_palm PF14792.1 GAM19229.1 - 2.5e-31 108.0 0.9 2.3e-29 101.6 0.1 2.5 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 GAM19229.1 - 2.8e-20 71.7 0.0 7.9e-20 70.3 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 GAM19229.1 - 1.3e-13 50.2 0.1 4.8e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 GAM19229.1 - 0.00018 21.6 3.3 0.0074 16.4 0.1 2.5 1 1 2 3 3 3 2 Helix-hairpin-helix domain SDA1 PF05285.7 GAM19229.1 - 0.00024 20.5 11.1 0.00024 20.5 7.7 2.6 3 0 0 3 3 3 1 SDA1 HHH_8 PF14716.1 GAM19229.1 - 0.0007 19.7 2.0 0.065 13.4 0.1 3.1 2 1 1 3 3 3 1 Helix-hairpin-helix domain Cwf_Cwc_15 PF04889.7 GAM19229.1 - 0.0021 17.8 11.1 0.0021 17.8 7.7 2.4 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein NTP_transf_2 PF01909.18 GAM19229.1 - 0.0061 16.8 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Suf PF05843.9 GAM19229.1 - 0.0071 16.1 1.2 0.0071 16.1 0.9 2.3 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 GAM19229.1 - 0.0074 16.0 2.2 0.0074 16.0 1.6 2.3 2 0 0 2 2 2 1 AUX/IAA family Spore_coat_CotO PF14153.1 GAM19229.1 - 0.015 14.7 13.1 0.012 15.0 3.8 2.5 2 0 0 2 2 2 0 Spore coat protein CotO YL1 PF05764.8 GAM19229.1 - 0.031 13.8 32.3 0.33 10.5 12.5 2.3 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.5 GAM19229.1 - 0.12 11.4 32.7 0.11 11.5 9.3 2.3 2 0 0 2 2 2 0 BUD22 HHH PF00633.18 GAM19229.1 - 0.21 11.3 1.0 12 5.8 0.1 3.0 3 0 0 3 3 2 0 Helix-hairpin-helix motif DUF2890 PF11081.3 GAM19229.1 - 0.41 10.6 21.3 0.29 11.1 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) FtsH_ext PF06480.10 GAM19229.1 - 0.43 10.7 3.0 32 4.7 1.8 2.8 2 0 0 2 2 2 0 FtsH Extracellular Ribosomal_S13 PF00416.17 GAM19229.1 - 0.45 11.0 13.0 0.092 13.2 0.6 3.5 1 1 0 2 2 2 0 Ribosomal protein S13/S18 SOBP PF15279.1 GAM19229.1 - 0.73 10.1 5.9 2.7 8.3 0.4 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Sporozoite_P67 PF05642.6 GAM19229.1 - 6.5 4.4 27.9 1.8 6.3 8.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen FG-GAP PF01839.18 GAM19231.1 - 1.7e-22 78.4 15.8 9.3e-06 25.1 0.3 6.9 6 0 0 6 6 6 6 FG-GAP repeat VCBS PF13517.1 GAM19231.1 - 3.9e-21 75.1 15.9 3.2e-08 33.7 0.4 5.4 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.1 GAM19231.1 - 1.9e-09 37.3 0.0 3.9e-07 29.7 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain BBS2_Mid PF14783.1 GAM19231.1 - 4e-09 36.2 0.4 0.42 10.4 0.0 6.0 6 1 0 6 6 6 3 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 GAM19231.1 - 1.9e-07 30.2 0.5 0.027 14.0 0.0 4.5 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.1 GAM19231.1 - 5.8e-07 29.5 12.3 0.00072 19.7 0.1 6.5 7 0 0 7 7 7 2 PQQ-like domain BBS2_C PF14782.1 GAM19231.1 - 0.001 17.7 0.2 1 7.8 0.0 3.9 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, C-terminal BBS1 PF14779.1 GAM19231.1 - 0.013 14.4 0.3 11 4.9 0.0 4.2 4 2 2 6 6 6 0 Ciliary BBSome complex subunit 1 TcdB_toxin_midN PF12256.3 GAM19231.1 - 0.087 12.2 6.9 0.77 9.1 0.1 4.6 3 1 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region KMP11 PF03037.11 GAM19231.1 - 0.31 11.6 4.1 2.1 8.9 2.1 2.5 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 SET PF00856.23 GAM19232.1 - 5.6e-11 43.0 0.1 5e-09 36.6 0.0 2.8 2 2 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 GAM19232.1 - 6.1e-09 35.8 0.4 1.2e-08 34.9 0.3 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Cad PF03596.8 GAM19233.1 - 0.008 15.8 1.2 0.017 14.8 0.8 1.5 1 0 0 1 1 1 1 Cadmium resistance transporter CTP_transf_2 PF01467.21 GAM19234.1 - 1.1e-19 70.9 0.0 2.1e-19 70.1 0.0 1.4 2 0 0 2 2 2 1 Cytidylyltransferase Peptidase_M15_3 PF08291.6 GAM19234.1 - 0.11 12.2 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Peptidase M15 EMP24_GP25L PF01105.19 GAM19236.1 - 1.3e-34 119.4 9.2 5.7e-21 75.0 0.4 2.3 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD DUF308 PF03729.8 GAM19236.1 - 0.0024 17.8 0.9 0.023 14.6 0.1 2.2 2 0 0 2 2 2 1 Short repeat of unknown function (DUF308) DUF3021 PF11457.3 GAM19236.1 - 0.62 9.9 6.2 1.5 8.6 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) Mer2 PF09074.5 GAM19237.1 - 0.058 13.3 1.5 0.1 12.5 1.1 1.5 1 1 0 1 1 1 0 Mer2 COMPASS-Shg1 PF05205.7 GAM19237.1 - 0.079 13.2 0.8 0.096 12.9 0.5 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Vps51 PF08700.6 GAM19237.1 - 0.096 12.5 1.5 2.4 8.0 0.2 2.5 2 1 0 2 2 2 0 Vps51/Vps67 Iron_permease PF04120.7 GAM19237.1 - 0.13 11.8 3.6 0.22 11.0 2.5 1.5 1 1 0 1 1 1 0 Low affinity iron permease WD40 PF00400.27 GAM19238.1 - 7.2e-42 139.8 29.2 4.5e-07 29.5 0.1 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Apc4_WD40 PF12894.2 GAM19238.1 - 0.00053 19.4 0.2 2.8 7.4 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 GAM19238.1 - 0.00055 18.1 5.8 0.1 10.6 0.1 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 CHCH PF06747.8 GAM19239.1 - 0.052 13.4 9.0 0.065 13.1 1.6 3.0 2 2 1 3 3 3 0 CHCH domain Cmc1 PF08583.5 GAM19239.1 - 0.063 13.0 11.9 3.5 7.4 2.2 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 GAM19239.1 - 5.9 7.0 7.9 3.8 7.7 0.6 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3128) Pkinase PF00069.20 GAM19240.1 - 2.1e-58 197.5 0.0 3.8e-57 193.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19240.1 - 1.7e-24 86.3 0.1 1e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM19240.1 - 0.00036 19.5 0.2 0.0053 15.7 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 GAM19240.1 - 0.00052 19.8 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family FGase PF05013.7 GAM19240.1 - 0.044 13.6 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Seadorna_VP7 PF07387.6 GAM19240.1 - 0.052 12.3 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 E1-E2_ATPase PF00122.15 GAM19242.1 - 3.7e-47 160.3 1.5 3.7e-47 160.3 1.1 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM19242.1 - 1.3e-18 67.1 7.2 1.3e-18 67.1 5.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM19242.1 - 6.7e-17 62.6 0.0 1.3e-16 61.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM19242.1 - 4.2e-14 53.1 0.1 2.1e-13 50.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM19242.1 - 1.1e-12 47.1 0.0 2.4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAM19242.1 - 1.2e-06 28.3 0.0 3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM19242.1 - 0.0053 16.3 0.1 0.082 12.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CorA PF01544.13 GAM19243.1 - 0.0026 16.8 18.7 0.0063 15.5 11.5 2.6 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 GAM19243.1 - 0.033 12.8 0.1 0.05 12.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 GAM19244.1 - 1.8e-42 141.7 15.5 1.1e-12 47.3 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM19244.1 - 2.6e-05 24.0 1.2 0.06 13.0 0.2 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Filo_VP35 PF02097.10 GAM19244.1 - 0.004 16.4 2.8 0.0058 15.8 1.9 1.2 1 0 0 1 1 1 1 Filoviridae VP35 DivIC PF04977.10 GAM19244.1 - 0.0088 15.5 9.6 0.012 15.0 0.2 2.6 2 0 0 2 2 2 1 Septum formation initiator FlaC_arch PF05377.6 GAM19244.1 - 0.018 14.9 0.1 0.059 13.2 0.1 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Nnf1 PF03980.9 GAM19244.1 - 0.074 13.0 6.6 0.15 12.0 4.5 1.5 1 0 0 1 1 1 0 Nnf1 DUF4175 PF13779.1 GAM19244.1 - 1.3 6.5 11.9 2 6.0 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 GAM19244.1 - 2.1 7.2 5.8 3.2 6.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3597 PF12200.3 GAM19244.1 - 3.7 7.9 8.1 0.86 9.9 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Abhydrolase_5 PF12695.2 GAM19245.1 - 1.2e-12 47.7 0.0 1.6e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM19245.1 - 4.3e-10 39.8 0.0 9e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM19245.1 - 8.6e-09 35.2 0.0 2e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 GAM19245.1 - 4e-05 23.0 0.0 5.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAM19245.1 - 0.00011 21.4 0.0 0.0011 18.2 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 GAM19245.1 - 0.047 13.2 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF818 PF05677.7 GAM19245.1 - 0.068 11.9 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.8 GAM19245.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein APG6 PF04111.7 GAM19246.1 - 8e-100 333.9 6.8 8e-100 333.9 4.7 2.2 2 0 0 2 2 2 1 Autophagy protein Apg6 DUF294_C PF10335.4 GAM19246.1 - 0.27 10.8 3.6 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain Claudin_3 PF06653.6 GAM19247.1 - 0.11 12.2 7.6 0.037 13.7 2.7 1.9 1 1 1 2 2 2 0 Tight junction protein, Claudin-like EpsG PF14897.1 GAM19247.1 - 1.4 7.8 8.6 0.25 10.2 1.4 2.0 1 1 0 2 2 2 0 EpsG family GTP_EFTU PF00009.22 GAM19248.1 - 4.2e-57 192.6 0.0 5.5e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM19248.1 - 1.6e-23 82.7 0.1 9.9e-23 80.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM19248.1 - 3.6e-14 52.6 2.7 7.6e-14 51.5 1.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM19248.1 - 7.2e-06 25.9 0.0 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAM19248.1 - 0.00047 19.7 1.0 0.0011 18.5 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 GAM19248.1 - 0.0093 16.4 0.0 0.026 15.0 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein MobB PF03205.9 GAM19248.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DisA_N PF02457.11 GAM19248.1 - 0.095 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding RRN3 PF05327.6 GAM19249.1 - 6.5e-87 291.9 28.6 1.4e-49 168.6 4.2 4.0 2 2 1 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 EHN PF06441.7 GAM19249.1 - 1.2 9.0 7.9 4.8 7.1 5.5 2.0 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Spt20 PF12090.3 GAM19249.1 - 6 6.1 14.9 4.5 6.5 6.3 2.5 2 1 0 2 2 2 0 Spt20 family F-box-like PF12937.2 GAM19251.1 - 0.03 14.0 0.1 0.084 12.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like PH PF00169.24 GAM19252.1 - 1.4e-09 38.1 0.0 1.4e-09 38.1 0.0 2.9 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM19252.1 - 9.9e-07 29.0 0.3 9.9e-07 29.0 0.2 4.5 3 3 1 4 4 4 1 Pleckstrin homology domain Myosin_tail_1 PF01576.14 GAM19252.1 - 0.00039 18.3 34.2 0.00039 18.3 23.7 3.5 1 1 3 4 4 4 2 Myosin tail IncA PF04156.9 GAM19252.1 - 0.0011 18.6 10.1 0.0011 18.6 7.0 8.1 1 1 8 9 9 9 4 IncA protein GAS PF13851.1 GAM19252.1 - 0.0046 16.1 23.0 0.0046 16.1 15.9 8.0 2 2 6 8 8 8 4 Growth-arrest specific micro-tubule binding PH_8 PF15409.1 GAM19252.1 - 0.006 16.6 0.8 0.062 13.3 0.5 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain CENP-F_leu_zip PF10473.4 GAM19252.1 - 0.0061 16.4 20.2 0.0061 16.4 14.0 9.4 1 1 8 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 GAM19252.1 - 0.007 15.5 74.0 0.024 13.8 3.9 6.9 1 1 6 8 8 8 5 Reovirus sigma C capsid protein DUF4557 PF15101.1 GAM19253.1 - 0.00045 20.1 1.4 0.00045 20.1 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) Acetyltransf_1 PF00583.19 GAM19254.1 - 1.3e-08 34.7 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM19254.1 - 4.9e-07 29.8 0.0 8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM19254.1 - 2.4e-05 24.4 0.0 3.6e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Exostosin PF03016.10 GAM19254.1 - 0.04 12.9 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Exostosin family Adaptin_N PF01602.15 GAM19255.1 - 9.4e-113 377.2 17.7 3.7e-112 375.3 11.9 2.0 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.5 GAM19255.1 - 2e-56 190.0 0.0 4e-56 189.0 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 GAM19255.1 - 1.7e-15 57.0 1.3 0.0014 18.8 0.0 5.8 2 2 3 5 5 5 5 HEAT repeats Cnd1 PF12717.2 GAM19255.1 - 4e-10 39.8 14.1 0.00018 21.4 1.9 4.5 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM19255.1 - 3.1e-06 26.8 4.6 0.65 10.2 0.1 6.8 7 0 0 7 7 7 2 HEAT repeat B2-adapt-app_C PF09066.5 GAM19255.1 - 0.00031 20.5 0.1 0.0011 18.8 0.1 2.0 1 1 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain DUF1241 PF06840.6 GAM19255.1 - 0.0056 15.9 0.7 0.028 13.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1241) HEAT_EZ PF13513.1 GAM19255.1 - 0.01 16.2 3.9 0.11 13.0 0.1 4.1 3 2 1 4 4 4 0 HEAT-like repeat Alpha_adaptin_C PF02296.11 GAM19255.1 - 0.021 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Vac14_Fab1_bd PF12755.2 GAM19255.1 - 0.08 13.3 5.4 11 6.5 0.0 4.7 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Syntaxin-6_N PF09177.6 GAM19256.1 - 0.11 12.8 0.0 0.11 12.8 0.0 4.2 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Racemase_4 PF13615.1 GAM19256.1 - 0.18 12.0 2.2 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Putative alanine racemase Bacillus_HBL PF05791.6 GAM19256.1 - 0.94 8.8 19.8 11 5.3 10.3 3.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 GAM19256.1 - 1 8.9 31.8 23 4.5 0.0 3.2 2 1 0 2 2 2 0 IncA protein TMCO5 PF14992.1 GAM19256.1 - 6 5.9 28.5 2 7.4 10.2 2.3 1 1 1 2 2 2 0 TMCO5 family SlyX PF04102.7 GAM19256.1 - 7.9 6.9 24.1 1.1 9.6 3.1 4.5 3 1 1 4 4 4 0 SlyX Pkinase PF00069.20 GAM19257.1 - 3.4e-52 177.1 0.1 1.4e-51 175.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19257.1 - 1e-32 113.2 0.0 1.8e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19257.1 - 0.0032 16.4 0.0 0.39 9.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAM19257.1 - 0.0047 16.7 0.0 0.35 10.5 0.0 2.9 2 2 2 4 4 4 2 Phosphotransferase enzyme family FNIP PF05725.7 GAM19258.1 - 5.7e-96 314.2 52.9 7.7e-14 51.3 1.1 11.2 6 2 7 13 13 13 12 FNIP Repeat Peptidase_C1 PF00112.18 GAM19259.1 - 6.5e-60 202.7 0.4 9.9e-60 202.1 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM19259.1 - 3.3e-14 52.8 4.7 6e-14 52.0 3.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Cation_efflux PF01545.16 GAM19260.1 - 1.3e-65 221.3 12.7 1.6e-65 221.0 8.8 1.1 1 0 0 1 1 1 1 Cation efflux family Cation_ATPase_C PF00689.16 GAM19260.1 - 0.71 9.3 8.8 0.037 13.5 1.8 1.8 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus BPD_transp_2 PF02653.11 GAM19260.1 - 1.5 7.7 11.6 3.2 6.6 0.2 2.4 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF3487 PF11990.3 GAM19261.1 - 0.64 9.4 9.7 0.69 9.3 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) G3P_acyltransf PF02660.10 GAM19261.1 - 0.79 9.2 9.9 0.82 9.2 6.9 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase ABC_membrane_3 PF13748.1 GAM19261.1 - 1.2 8.1 10.4 1.5 7.8 7.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Claudin_2 PF13903.1 GAM19261.1 - 2.7 7.6 7.3 3.2 7.4 5.1 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 GAM19261.1 - 2.8 7.4 5.6 3.3 7.2 3.9 1.1 1 0 0 1 1 1 0 IncA protein Clc-like PF07062.7 GAM19261.1 - 3.2 6.9 8.6 3.1 6.9 6.0 1.1 1 0 0 1 1 1 0 Clc-like PrgI PF12666.2 GAM19261.1 - 5 7.3 11.9 7.4 6.8 8.2 1.4 1 1 0 1 1 1 0 PrgI family protein Laminin_EGF PF00053.19 GAM19262.1 - 0.0022 17.8 23.0 0.03 14.2 3.6 2.9 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 GAM19262.1 - 0.066 13.3 1.2 0.066 13.3 0.9 3.2 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.2 GAM19262.1 - 0.2 11.7 12.9 0.11 12.6 1.3 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF Alpha_L_fucos PF01120.12 GAM19263.1 - 3.6e-58 197.1 1.3 7e-57 192.8 0.9 2.0 1 1 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 GAM19263.1 - 0.0014 18.6 0.2 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 zf-CCHC PF00098.18 GAM19264.1 - 1.6e-37 125.6 43.0 2.6e-08 33.3 1.1 5.3 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 GAM19264.1 - 6.8e-09 35.2 30.8 0.11 12.1 0.2 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 GAM19264.1 - 4e-06 26.4 35.4 0.058 13.1 0.3 5.2 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 GAM19264.1 - 1.4e-05 24.4 22.1 0.088 12.3 0.9 5.2 4 1 1 5 5 5 5 Zinc knuckle EPL1 PF10513.4 GAM19266.1 - 6.4e-27 94.7 0.6 6.4e-27 94.7 0.4 5.0 3 2 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.1 GAM19266.1 - 1.1e-23 83.2 5.9 1.1e-23 83.2 4.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 GAM19266.1 - 3.7e-18 65.4 2.7 3.7e-18 65.4 1.9 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.20 GAM19266.1 - 4.9e-17 61.6 0.3 1.2e-16 60.3 0.2 1.7 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 GAM19266.1 - 4.2e-13 48.3 5.1 4.2e-13 48.3 3.5 2.8 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 GAM19266.1 - 3.7e-11 42.5 28.7 2.6e-09 36.5 5.2 3.4 3 1 0 3 3 3 2 PHD-finger C1_1 PF00130.17 GAM19266.1 - 0.0047 16.6 1.0 0.0047 16.6 0.7 3.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 GAM19266.1 - 6.8 6.7 30.0 0.016 15.1 4.8 3.3 3 1 1 4 4 4 0 RING-like domain DUF1990 PF09348.5 GAM19267.1 - 3.4e-46 156.7 0.2 4.3e-46 156.4 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) UPF0183 PF03676.9 GAM19269.1 - 9e-101 337.3 6.7 6.6e-50 169.8 0.0 3.0 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) CHCH PF06747.8 GAM19270.1 - 0.014 15.2 1.8 0.014 15.2 1.2 2.9 2 1 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 GAM19270.1 - 0.073 12.8 10.1 0.53 10.0 1.4 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like C8 PF08742.6 GAM19270.1 - 2.1 8.6 5.9 1.3 9.3 2.3 1.9 1 1 1 2 2 2 0 C8 domain Pet191_N PF10203.4 GAM19270.1 - 3.5 7.7 11.2 5 7.2 4.6 2.6 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 VPS9 PF02204.13 GAM19271.1 - 4.7e-28 97.2 1.4 9.8e-28 96.2 0.2 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain LETM1 PF07766.8 GAM19272.1 - 1.8e-77 260.0 7.0 1.8e-77 260.0 4.8 1.6 2 0 0 2 2 2 1 LETM1-like protein Amidinotransf PF02274.12 GAM19273.1 - 7.6e-64 215.5 0.4 8.8e-64 215.2 0.2 1.0 1 0 0 1 1 1 1 Amidinotransferase Apo-CIII PF05778.7 GAM19273.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) PP2C PF00481.16 GAM19275.1 - 2.7e-54 184.2 0.0 6.6e-54 182.9 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM19275.1 - 6.3e-06 25.7 0.0 4e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.1 GAM19275.1 - 0.00042 20.0 9.9 0.45 10.7 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 GAM19275.1 - 0.1 12.7 9.3 5.3 7.4 0.0 5.4 3 2 2 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 GAM19275.1 - 3.1 7.5 16.0 5.6 6.6 0.0 4.4 3 2 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF3530 PF12048.3 GAM19276.1 - 0.0021 17.0 3.4 0.0028 16.7 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) FAM176 PF14851.1 GAM19276.1 - 0.0087 15.7 1.3 0.012 15.3 0.9 1.2 1 0 0 1 1 1 1 FAM176 family Gastrin PF00918.12 GAM19276.1 - 0.0096 16.7 0.5 0.012 16.3 0.3 1.3 1 0 0 1 1 1 1 Gastrin/cholecystokinin family Shisa PF13908.1 GAM19276.1 - 0.012 15.8 0.7 0.014 15.5 0.5 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF808 PF05661.7 GAM19276.1 - 0.016 14.0 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) ETRAMP PF09716.5 GAM19276.1 - 0.023 14.6 1.3 0.061 13.2 0.9 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4128 PF13554.1 GAM19276.1 - 0.026 14.1 0.2 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage related domain of unknown function YfhO PF09586.5 GAM19276.1 - 0.038 12.0 0.3 0.046 11.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pro-rich PF15240.1 GAM19276.1 - 0.039 14.0 3.3 0.051 13.6 2.3 1.3 1 1 0 1 1 1 0 Proline-rich CemA PF03040.9 GAM19276.1 - 0.058 13.0 1.1 0.059 12.9 0.7 1.1 1 0 0 1 1 1 0 CemA family SID-1_RNA_chan PF13965.1 GAM19276.1 - 0.074 11.2 2.3 0.087 10.9 1.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2140 PF09911.4 GAM19276.1 - 0.076 12.1 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Lig_chan PF00060.21 GAM19276.1 - 0.085 12.5 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4446 PF14584.1 GAM19276.1 - 0.092 12.5 0.5 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Tetraspannin PF00335.15 GAM19276.1 - 0.096 11.9 0.3 0.095 11.9 0.2 1.1 1 0 0 1 1 1 0 Tetraspanin family PDCD2_C PF04194.8 GAM19276.1 - 0.12 11.9 4.8 0.17 11.5 3.3 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Mucin PF01456.12 GAM19276.1 - 0.13 11.9 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein WBP-1 PF11669.3 GAM19276.1 - 0.27 11.3 1.7 0.42 10.7 1.2 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 Gag_spuma PF03276.9 GAM19276.1 - 0.55 8.4 6.8 0.63 8.3 4.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF775 PF05603.7 GAM19276.1 - 0.79 9.2 8.2 1.1 8.7 5.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Tom22 PF04281.8 GAM19276.1 - 5.2 6.6 8.4 7.7 6.0 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Pkinase PF00069.20 GAM19278.1 - 1.3e-46 158.8 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19278.1 - 2.1e-19 69.5 0.0 2.4e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19278.1 - 1.9e-06 27.0 0.0 1.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM19278.1 - 0.0033 16.5 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 GAM19279.1 - 5.5e-06 25.7 0.2 1.5e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Hex_IIIa PF02455.11 GAM19279.1 - 0.39 9.3 9.2 0.51 8.9 6.4 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Mucin PF01456.12 GAM19279.1 - 3 7.6 25.6 0.19 11.4 13.7 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DNA_pol_viral_N PF00242.12 GAM19279.1 - 5 6.0 14.9 7.8 5.4 10.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ndc1_Nup PF09531.5 GAM19279.1 - 6.9 4.9 12.2 9.4 4.5 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FNIP PF05725.7 GAM19280.1 - 3.9e-28 97.1 18.7 7.5e-13 48.2 1.1 5.2 5 1 0 5 5 5 4 FNIP Repeat Acetyltransf_7 PF13508.1 GAM19281.1 - 4.1e-09 36.4 0.0 1.1e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM19281.1 - 2e-08 34.3 0.1 7.1e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM19281.1 - 2.1e-07 30.8 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM19281.1 - 2.5e-05 23.9 0.0 5.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAM19281.1 - 0.04 13.7 0.2 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HlyD_2 PF12700.2 GAM19281.1 - 3.7 6.6 15.1 1.7 7.7 2.0 2.3 2 0 0 2 2 2 0 HlyD family secretion protein Porin_3 PF01459.17 GAM19282.1 - 2.5e-23 82.7 0.3 2.8e-23 82.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.1 GAM19282.1 - 0.13 12.1 4.7 0.14 12.0 0.7 2.2 1 1 0 2 2 2 0 Outer membrane protein beta-barrel domain Sec23_trunk PF04811.10 GAM19286.1 - 4.4e-43 147.3 0.0 8.3e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM19286.1 - 7.1e-24 83.2 0.1 1.8e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAM19286.1 - 2.9e-17 62.9 0.0 7.2e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM19286.1 - 6.3e-13 48.0 2.7 6.3e-13 48.0 1.9 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAM19286.1 - 7e-07 28.8 0.1 3e-06 26.8 0.1 2.2 1 0 0 1 1 1 1 Gelsolin repeat G8 PF10162.4 GAM19287.1 - 2.1e-24 85.7 0.4 4.6e-24 84.5 0.3 1.7 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.1 GAM19287.1 - 0.014 13.8 0.1 0.023 13.2 0.1 1.2 1 0 0 1 1 1 0 Amnionless ketoacyl-synt PF00109.21 GAM19288.1 - 2.1e-71 240.4 0.0 3.5e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 GAM19288.1 - 1.9e-53 180.9 0.0 4.9e-53 179.6 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.16 GAM19288.1 - 3.4e-53 181.0 0.0 8.2e-53 179.7 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM19288.1 - 1.1e-39 134.8 0.2 3.8e-39 133.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 GAM19288.1 - 9.9e-35 119.8 0.1 5.9e-34 117.3 0.3 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAM19288.1 - 4.2e-26 91.7 0.0 7.4e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM19288.1 - 2.3e-25 89.4 2.4 4.6e-25 88.4 0.0 2.8 5 0 0 5 5 5 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 GAM19288.1 - 7.4e-11 43.0 0.1 7.1e-10 39.8 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM19288.1 - 2.6e-07 30.3 0.0 6.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 GAM19288.1 - 5e-07 28.7 0.2 1.3e-06 27.2 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 GAM19288.1 - 8.4e-07 29.1 0.1 3.9e-06 27.0 0.0 2.3 2 0 0 2 2 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM19288.1 - 2.5e-06 26.6 0.0 4.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Metallophos PF00149.23 GAM19289.1 - 2.9e-12 46.4 1.2 4.3e-12 45.8 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DSPc PF00782.15 GAM19290.1 - 2.4e-32 111.3 0.0 2.4e-32 111.3 0.0 2.2 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM19290.1 - 9.6e-05 21.8 2.2 0.00013 21.4 0.1 2.0 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAM19290.1 - 0.0039 17.2 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate zf-RING_2 PF13639.1 GAM19291.1 - 6.3e-12 45.1 5.7 1.4e-11 44.0 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM19291.1 - 1.9e-08 33.8 2.8 3.8e-08 32.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM19291.1 - 8e-08 32.2 3.0 2.5e-07 30.6 2.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM19291.1 - 8.1e-08 31.8 3.4 1.6e-07 30.9 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM19291.1 - 1.2e-06 28.3 6.3 2.7e-06 27.3 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM19291.1 - 1.3e-06 27.8 6.6 3.2e-06 26.6 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM19291.1 - 0.0004 20.1 1.3 0.0011 18.6 0.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 GAM19291.1 - 0.0018 17.8 6.1 0.004 16.7 4.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 GAM19291.1 - 0.048 13.7 5.9 0.13 12.2 4.1 1.8 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 GAM19291.1 - 0.056 13.2 1.5 0.13 12.0 1.0 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain ORF6N PF10543.4 GAM19291.1 - 0.067 13.2 0.9 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 ORF6N domain zf-RING_UBOX PF13445.1 GAM19291.1 - 0.29 10.8 2.4 0.69 9.6 1.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger NTP_transferase PF00483.18 GAM19292.1 - 3.9e-26 91.8 0.0 5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 GAM19292.1 - 1.7e-08 33.5 5.4 4.5e-07 29.0 0.9 3.8 3 1 1 4 4 4 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAM19292.1 - 1.5e-06 28.3 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Ribosomal_L7Ae PF01248.21 GAM19292.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SPRR2 PF14820.1 GAM19293.1 - 0.31 10.9 8.6 0.45 10.4 6.0 1.2 1 0 0 1 1 1 0 Small proline-rich 2 Ank_2 PF12796.2 GAM19294.1 - 4.2e-16 59.0 11.6 0.0085 16.4 0.0 9.7 6 3 3 9 9 9 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19294.1 - 4.9e-10 38.6 14.8 12 6.5 0.0 13.1 14 0 0 14 14 14 2 Ankyrin repeat Ank_4 PF13637.1 GAM19294.1 - 5.4e-07 29.9 12.3 4.8 7.8 0.1 10.0 11 1 1 12 12 12 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19294.1 - 2.7e-06 27.4 8.3 2.4 8.5 0.0 10.2 12 0 0 12 12 12 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19294.1 - 0.00073 19.2 5.8 20 5.2 0.0 8.4 9 0 0 9 9 9 1 Ankyrin repeat CDC37_C PF08564.5 GAM19294.1 - 0.069 12.9 0.1 23 4.8 0.0 3.4 3 0 0 3 3 3 0 Cdc37 C terminal domain PX PF00787.19 GAM19295.1 - 0.11 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 PX domain LBR_tudor PF09465.5 GAM19296.1 - 7.4e-05 22.2 0.5 0.00014 21.4 0.4 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Agenet PF05641.7 GAM19296.1 - 0.0035 17.4 0.5 0.0067 16.5 0.1 1.7 2 0 0 2 2 2 1 Agenet domain SSP160 PF06933.6 GAM19296.1 - 0.3 9.0 13.5 0.4 8.5 9.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 GAM19296.1 - 0.58 9.9 17.7 0.92 9.2 12.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RAG1 PF12940.2 GAM19297.1 - 0.0016 16.8 0.0 0.0021 16.4 0.0 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) Fer2_3 PF13085.1 GAM19297.1 - 0.11 12.3 0.2 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ank_2 PF12796.2 GAM19298.1 - 5.5e-16 58.6 16.8 0.0052 17.0 0.1 8.8 6 2 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19298.1 - 6.2e-08 32.1 10.3 35 5.0 0.0 11.3 13 0 0 13 13 13 0 Ankyrin repeat Ank_5 PF13857.1 GAM19298.1 - 7.6e-08 32.3 5.7 5.7 7.3 0.0 10.2 11 2 2 13 13 13 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM19298.1 - 2.6e-05 24.6 12.9 4.5 7.9 0.1 9.3 8 2 1 9 9 9 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19298.1 - 0.01 15.6 4.6 9.2 6.2 0.0 6.4 8 0 0 8 8 8 0 Ankyrin repeat Ank_2 PF12796.2 GAM19299.1 - 3.1e-07 30.6 0.8 0.015 15.6 0.0 5.3 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19299.1 - 1.5e-05 24.7 0.7 0.99 9.8 0.0 6.4 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 GAM19299.1 - 0.00018 21.9 0.6 17 6.1 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19299.1 - 0.049 13.9 4.9 9.3 6.6 0.0 5.8 7 1 1 8 8 8 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM19299.1 - 0.08 12.7 0.1 21 5.1 0.0 4.0 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.2 GAM19300.1 - 2.7e-09 37.2 3.8 4.5e-05 23.7 0.6 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19300.1 - 2.2e-05 24.2 2.9 0.31 11.4 0.0 5.6 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 GAM19300.1 - 0.00031 20.8 0.3 7.3 6.9 0.0 4.7 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM19300.1 - 0.0024 18.3 2.9 4.7 7.8 0.0 4.2 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM19300.1 - 0.008 15.9 0.2 4.7 7.2 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 GAM19301.1 - 1.3e-06 28.6 2.9 0.3 11.4 0.0 5.3 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19301.1 - 0.00028 20.8 7.1 22 5.7 0.0 8.0 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.1 GAM19301.1 - 0.0036 17.7 6.4 3.5 8.2 0.0 6.6 6 2 2 8 8 8 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM19302.1 - 1.9e-09 37.7 0.3 0.00096 19.4 0.0 5.7 3 2 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19302.1 - 5.1e-05 23.1 5.8 0.22 11.8 0.0 7.1 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.1 GAM19302.1 - 0.0004 20.8 8.0 0.52 10.8 0.0 7.2 7 2 1 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19302.1 - 0.0046 16.6 0.7 0.44 10.4 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 GAM19302.1 - 0.0068 16.6 3.5 3.4 8.0 0.0 5.7 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM19303.1 - 2e-06 28.0 4.0 0.024 14.9 0.3 3.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM19303.1 - 0.00079 19.5 0.4 18 5.7 0.0 4.9 5 1 1 6 6 6 1 Ankyrin repeats (many copies) PPR_3 PF13812.1 GAM19303.1 - 0.052 13.8 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ank_2 PF12796.2 GAM19304.1 - 4.9e-09 36.4 0.3 0.00015 22.0 0.1 4.7 3 3 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19304.1 - 1.8e-06 27.6 3.6 0.15 12.4 0.0 7.0 7 2 1 8 8 8 1 Ankyrin repeat Ank PF00023.25 GAM19304.1 - 0.001 18.7 2.0 1.3 8.9 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Spo0A_C PF08769.6 GAM19304.1 - 0.013 15.3 0.0 0.22 11.3 0.0 2.9 3 0 0 3 3 3 0 Sporulation initiation factor Spo0A C terminal Ank_5 PF13857.1 GAM19304.1 - 0.015 15.5 1.9 16 5.8 0.0 5.6 4 1 2 6 6 6 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM19304.1 - 0.024 15.1 6.7 0.37 11.3 0.0 5.7 8 0 0 8 8 8 0 Ankyrin repeats (many copies) DUF3635 PF12330.3 GAM19304.1 - 0.025 14.6 0.1 0.17 11.9 0.0 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3635) Acetyltransf_1 PF00583.19 GAM19305.1 - 1.5e-11 44.1 0.0 2.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM19305.1 - 4.7e-11 42.7 0.2 9e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM19305.1 - 2e-06 27.9 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM19305.1 - 4.4e-05 23.1 0.0 7.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.1 GAM19305.1 - 0.00016 22.2 0.2 0.015 15.8 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM19305.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM19305.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_L10 PF00466.15 GAM19306.1 - 5.5e-19 67.9 1.2 9.1e-19 67.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 GAM19306.1 - 1.3e-16 60.7 9.7 1.3e-16 60.7 6.7 2.5 2 1 1 3 3 3 1 60s Acidic ribosomal protein Amidohydro_2 PF04909.9 GAM19307.1 - 1.6e-50 172.2 0.0 1.8e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M19 PF01244.16 GAM19307.1 - 0.087 11.7 0.0 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) AP_endonuc_2_N PF07582.7 GAM19307.1 - 0.12 11.9 0.1 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus Kelch_1 PF01344.20 GAM19308.1 - 7.8e-06 25.3 13.8 0.0073 15.8 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 GAM19308.1 - 3.9e-05 23.6 15.7 0.67 10.2 0.1 5.9 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 GAM19308.1 - 0.00014 21.5 9.0 0.31 10.8 0.1 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM19308.1 - 0.067 12.9 6.2 7.2 6.5 0.1 4.6 5 0 0 5 5 5 0 Kelch motif tRNA_anti-like PF12869.2 GAM19308.1 - 0.096 12.1 0.1 0.44 10.0 0.0 1.9 2 0 0 2 2 2 0 tRNA_anti-like STN PF07660.9 GAM19308.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Kelch_5 PF13854.1 GAM19308.1 - 0.11 12.5 13.9 1.4 8.9 0.1 4.7 5 1 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 GAM19308.1 - 0.7 10.1 9.9 37 4.6 0.0 5.5 5 1 0 5 5 5 0 Galactose oxidase, central domain YchF-GTPase_C PF06071.8 GAM19309.1 - 4.1e-40 135.4 0.9 8e-40 134.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 GAM19309.1 - 4.5e-16 58.8 0.0 2e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM19309.1 - 2.6e-06 26.7 0.0 4.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 GAM19309.1 - 0.091 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein MR_MLE PF01188.16 GAM19310.1 - 7.1e-18 64.8 0.5 1.5e-17 63.8 0.3 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 GAM19310.1 - 1.3e-13 50.8 0.0 3.3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 GAM19310.1 - 1.3e-06 28.4 0.0 4.4e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain COX6B PF02297.12 GAM19311.1 - 2.5e-18 65.8 4.9 2.5e-18 65.8 3.4 1.5 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb DUF1127 PF06568.6 GAM19311.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DUF4355 PF14265.1 GAM19311.1 - 2.7 7.9 7.3 0.85 9.5 3.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4355) SNF2_N PF00176.18 GAM19312.1 - 1e-76 257.5 0.1 1e-76 257.5 0.1 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 GAM19312.1 - 3e-16 59.1 1.0 3e-16 59.1 0.7 2.9 3 0 0 3 3 3 1 Bromodomain Helicase_C PF00271.26 GAM19312.1 - 1e-12 47.7 0.0 1.5e-11 43.9 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 GAM19312.1 - 5.4e-11 42.1 7.2 5.4e-11 42.1 5.0 3.2 2 0 0 2 2 2 1 HSA SnAC PF14619.1 GAM19312.1 - 1.6e-07 31.3 1.9 1.6e-07 31.3 1.4 4.6 4 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 GAM19312.1 - 0.00031 20.0 0.1 0.00077 18.8 0.0 1.7 1 0 0 1 1 1 1 QLQ zf-HIT PF04438.11 GAM19313.1 - 0.00094 18.7 5.6 0.0013 18.3 3.9 1.2 1 0 0 1 1 1 1 HIT zinc finger Daxx PF03344.10 GAM19313.1 - 0.044 12.2 23.8 0.054 11.9 16.5 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 GAM19313.1 - 3.4 6.8 30.5 5.1 6.2 21.2 1.3 1 0 0 1 1 1 0 SDA1 Cna_B PF05738.8 GAM19315.1 - 0.00042 20.0 6.8 0.0029 17.3 0.1 3.9 4 1 0 4 4 4 2 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM19315.1 - 0.024 14.6 3.5 3.8 7.6 0.1 3.5 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain RhoGAP PF00620.22 GAM19316.1 - 1.3e-30 106.0 0.0 3.2e-30 104.7 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain RPEL PF02755.10 GAM19316.1 - 0.00044 19.4 0.2 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 1 RPEL repeat DUF1708 PF08101.6 GAM19316.1 - 0.018 13.8 0.0 0.042 12.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) Aldo_ket_red PF00248.16 GAM19317.1 - 4.6e-08 32.2 0.0 7.3e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L13 PF00572.13 GAM19318.1 - 1.5e-44 151.1 0.2 1.5e-44 151.1 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 Birna_VP5 PF03042.9 GAM19318.1 - 0.072 12.5 0.1 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Birnavirus VP5 protein BTB_2 PF02214.17 GAM19319.1 - 2.2e-13 50.2 0.0 4.7e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUSP PF06337.7 GAM19319.1 - 3.5e-10 40.1 0.0 8.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 DUSP domain FtsX PF02687.16 GAM19320.1 - 1.9e-29 101.8 31.4 9.1e-19 67.3 7.3 4.6 4 1 1 5 5 5 2 FtsX-like permease family MacB_PCD PF12704.2 GAM19320.1 - 0.0017 17.9 3.3 0.015 14.8 0.1 3.7 4 0 0 4 4 4 1 MacB-like periplasmic core domain eIF-3_zeta PF05091.7 GAM19321.1 - 6.8e-140 467.1 0.6 7.8e-140 466.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NUFIP1 PF10453.4 GAM19322.1 - 4.9e-14 51.5 4.7 4.9e-14 51.5 3.3 2.8 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Mucin PF01456.12 GAM19322.1 - 7.5 6.3 17.5 1.6 8.4 9.5 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein NARG2_C PF10505.4 GAM19323.1 - 9.5e-15 54.3 0.0 3.3e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus CAF-1_p150 PF11600.3 GAM19323.1 - 0.0001 21.7 47.0 0.0001 21.7 32.6 4.5 5 0 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-CCCH PF00642.19 GAM19323.1 - 0.056 13.1 1.2 0.12 12.1 0.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SET PF00856.23 GAM19323.1 - 0.26 11.5 8.1 0.27 11.5 2.8 2.8 3 0 0 3 3 3 0 SET domain Ycf1 PF05758.7 GAM19323.1 - 0.4 8.3 24.0 0.0042 14.8 10.9 1.9 2 0 0 2 2 2 0 Ycf1 Kelch_3 PF13415.1 GAM19324.1 - 0.0014 18.6 0.0 6.4 7.0 0.0 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM19324.1 - 0.0032 17.5 4.9 8.3 6.7 0.0 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM19324.1 - 0.065 13.0 0.2 0.75 9.6 0.0 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 GAM19324.1 - 0.066 12.9 4.8 1.4 8.7 0.0 4.1 5 0 0 5 5 5 0 Galactose oxidase, central domain Endotoxin_N PF03945.9 GAM19325.1 - 1.7e-30 106.0 3.2 2.5e-30 105.5 2.2 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain TSP_3 PF02412.13 GAM19328.1 - 2.1 7.8 11.4 1.7 8.1 4.2 2.6 2 0 0 2 2 2 0 Thrombospondin type 3 repeat EF-hand_5 PF13202.1 GAM19329.1 - 0.9 8.9 15.4 0.42 10.0 1.4 3.4 3 0 0 3 3 3 0 EF hand TSP_3 PF02412.13 GAM19329.1 - 2.6 7.5 11.9 1.6 8.2 4.2 2.6 2 0 0 2 2 2 0 Thrombospondin type 3 repeat EF-hand_1 PF00036.27 GAM19329.1 - 4.9 6.6 14.4 2.6 7.5 1.7 3.5 3 0 0 3 3 3 0 EF hand Cpn60_TCP1 PF00118.19 GAM19331.1 - 0.015 13.9 0.3 0.026 13.1 0.2 1.3 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family 2OG-FeII_Oxy_3 PF13640.1 GAM19332.1 - 3.8e-11 43.3 0.1 5.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM19332.1 - 4.5e-10 39.0 0.3 7.6e-10 38.2 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 GAM19332.1 - 0.00013 22.1 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase TauD PF02668.11 GAM19332.1 - 0.031 13.9 0.3 0.18 11.4 0.0 1.7 1 1 1 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Oxygenase-NA PF09859.4 GAM19332.1 - 0.045 13.0 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Ribosomal_60s PF00428.14 GAM19333.1 - 1.2e-23 83.2 11.3 1.4e-23 83.0 7.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 GAM19333.1 - 0.27 11.1 4.8 0.34 10.7 3.3 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PepSY_2 PF13670.1 GAM19333.1 - 4.7 7.1 9.1 3.4 7.6 5.0 1.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain SDA1 PF05285.7 GAM19335.1 - 0.09 12.0 15.4 0.16 11.2 10.7 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 GAM19335.1 - 0.16 9.9 11.8 0.23 9.4 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAM19335.1 - 0.21 9.4 18.4 0.32 8.8 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 GAM19335.1 - 0.26 11.3 8.8 0.67 9.9 6.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3439 PF11921.3 GAM19335.1 - 0.61 9.8 10.8 1.6 8.4 7.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nop25 PF09805.4 GAM19335.1 - 1.1 9.2 10.6 2.7 8.0 7.3 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.5 GAM19335.1 - 2.3 7.2 14.9 4.1 6.3 10.3 1.4 1 0 0 1 1 1 0 BUD22 CDK5_activator PF03261.10 GAM19335.1 - 7.1 5.8 11.4 0.32 10.2 3.5 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein CobT PF06213.7 GAM19335.1 - 7.3 5.6 18.6 12 4.8 12.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cnd1 PF12717.2 GAM19336.1 - 7.3e-57 192.0 11.2 3.9e-51 173.4 0.7 5.2 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM19336.1 - 3.5e-12 45.2 8.1 0.041 13.9 0.2 7.2 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 GAM19336.1 - 3.2e-10 40.1 3.1 0.0067 16.6 0.0 4.7 3 1 1 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 GAM19336.1 - 9.2e-07 27.5 8.8 0.00013 20.4 0.2 3.1 2 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 GAM19336.1 - 9.9e-06 24.7 5.6 0.00064 18.7 0.2 2.8 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 GAM19336.1 - 0.0014 19.0 5.5 4.5 7.8 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat Cohesin_HEAT PF12765.2 GAM19336.1 - 0.0015 18.4 2.2 4 7.4 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion PBP1_TM PF14812.1 GAM19336.1 - 0.0018 18.5 0.5 0.0018 18.5 0.4 4.9 5 0 0 5 5 5 2 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGEF_N_2 PF14663.1 GAM19336.1 - 0.17 11.8 3.3 1.5 8.8 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DDRGK PF09756.4 GAM19336.1 - 3.8 6.8 23.6 0.026 13.9 5.5 2.5 2 0 0 2 2 2 0 DDRGK domain HutD PF05962.6 GAM19338.1 - 1.8e-27 96.2 0.1 1.9e-23 83.1 0.0 2.2 2 0 0 2 2 2 2 HutD FNIP PF05725.7 GAM19339.1 - 4.8e-54 180.0 16.4 1.2e-14 54.0 0.2 7.9 6 2 3 9 9 9 6 FNIP Repeat LRR_1 PF00560.28 GAM19339.1 - 0.97 9.7 7.9 1e+02 3.5 0.1 5.9 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 GAM19339.1 - 1.2 9.6 8.4 1.2e+02 3.5 0.0 6.8 10 0 0 10 10 10 0 Leucine rich repeat LRR_6 PF13516.1 GAM19339.1 - 1.4 9.2 9.7 1.4e+02 3.0 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 GAM19339.1 - 4.6 6.9 8.6 13 5.5 0.1 4.9 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Myosin_head PF00063.16 GAM19340.1 - 9e-273 906.4 0.4 9e-273 906.4 0.2 2.6 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 GAM19340.1 - 1.9e-102 343.5 354.6 3.6e-50 170.6 101.5 6.3 1 1 3 4 4 4 4 Myosin tail Myosin_N PF02736.14 GAM19340.1 - 1.7e-14 53.1 0.4 4.5e-14 51.8 0.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 GAM19340.1 - 2.5e-13 50.1 266.9 3e-05 23.6 11.0 10.4 1 1 7 9 9 9 6 Intermediate filament protein IQ PF00612.22 GAM19340.1 - 0.00045 19.6 4.0 0.0009 18.6 0.7 2.8 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_19 PF13245.1 GAM19340.1 - 0.037 13.7 0.5 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_35 PF14516.1 GAM19341.1 - 0.069 11.7 0.0 0.14 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Ank_2 PF12796.2 GAM19343.1 - 0.0038 17.5 1.9 29 5.1 0.0 4.4 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) TraG-D_C PF12696.2 GAM19343.1 - 0.096 12.5 0.6 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG FUN14 PF04930.10 GAM19344.1 - 6.2e-18 64.9 1.7 1.7e-17 63.5 0.0 2.3 1 1 1 2 2 2 1 FUN14 family Auxin_canalis PF05703.6 GAM19344.1 - 0.02 14.7 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Auxin canalisation TIG PF01833.19 GAM19345.1 - 0.00011 22.1 24.0 0.0037 17.2 1.4 4.6 4 0 0 4 4 4 3 IPT/TIG domain EGF_2 PF07974.8 GAM19345.1 - 0.00047 20.2 9.8 0.0011 19.1 6.8 1.7 1 0 0 1 1 1 1 EGF-like domain DUF1049 PF06305.6 GAM19345.1 - 0.038 13.4 0.8 0.072 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Fz PF01392.17 GAM19346.1 - 7.1e-05 23.1 3.0 0.00015 22.1 2.1 1.5 1 0 0 1 1 1 1 Fz domain SR-25 PF10500.4 GAM19347.1 - 0.3 10.5 9.8 0.43 10.0 6.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EGF_2 PF07974.8 GAM19348.1 - 0.22 11.7 14.2 0.76 9.9 9.8 2.0 1 0 0 1 1 1 0 EGF-like domain EB PF01683.13 GAM19349.1 - 0.00039 20.4 4.4 0.00088 19.2 3.0 1.5 1 0 0 1 1 1 1 EB module EGF_2 PF07974.8 GAM19349.1 - 0.0091 16.1 17.2 0.022 14.8 11.9 1.7 1 0 0 1 1 1 1 EGF-like domain DUF1996 PF09362.5 GAM19350.1 - 1.1e-39 136.5 1.8 1.7e-39 135.9 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Polysacc_lyase PF14099.1 GAM19351.1 - 1.4e-12 47.8 6.2 1.8e-12 47.3 4.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase Polysacc_lyase PF14099.1 GAM19352.1 - 1.6e-12 47.5 3.7 2.3e-12 47.0 2.6 1.2 1 0 0 1 1 1 1 Polysaccharide lyase Sporozoite_P67 PF05642.6 GAM19352.1 - 0.036 11.9 0.1 0.029 12.2 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAM19352.1 - 0.7 9.6 14.6 0.17 11.6 6.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 GAM19352.1 - 2.4 6.0 10.2 3.7 5.4 7.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nol1_Nop2_Fmu PF01189.12 GAM19353.1 - 1.5e-28 99.9 0.0 5.2e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 GAM19353.1 - 8.8e-10 38.3 0.0 1e-07 31.6 0.0 3.2 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM19353.1 - 6.3e-06 26.4 0.0 2.1e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM19353.1 - 6.8e-06 26.6 0.1 9.1e-05 23.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM19353.1 - 3.5e-05 23.2 0.0 0.00043 19.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM19353.1 - 6.4e-05 22.9 0.0 0.00059 19.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM19353.1 - 0.00017 20.8 0.0 0.0067 15.5 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 GAM19353.1 - 0.00094 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 GAM19353.1 - 0.0045 17.4 0.0 0.11 12.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Fibrillarin PF01269.12 GAM19353.1 - 0.012 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_23 PF13489.1 GAM19353.1 - 0.016 14.9 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 GAM19353.1 - 0.022 13.7 0.0 0.085 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.14 GAM19353.1 - 0.023 14.2 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 GAM19353.1 - 0.037 14.5 1.8 2.8 8.4 0.0 3.4 4 0 0 4 4 4 0 Methyltransferase domain SART-1 PF03343.8 GAM19353.1 - 0.26 9.5 11.1 0.026 12.8 0.4 2.0 2 0 0 2 2 2 0 SART-1 family PBP1_TM PF14812.1 GAM19353.1 - 0.46 10.8 11.0 1.2 9.5 2.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vfa1 PF08432.5 GAM19353.1 - 8.1 6.4 9.4 0.85 9.6 1.7 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HeLo PF14479.1 GAM19354.1 - 0.016 14.9 1.2 0.53 9.9 0.8 2.1 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF3713 PF12506.3 GAM19354.1 - 0.017 15.2 1.9 0.018 15.1 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3713) DUF3496 PF12001.3 GAM19354.1 - 0.13 12.4 4.0 0.24 11.6 2.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) DUF342 PF03961.8 GAM19354.1 - 0.22 9.9 3.3 0.26 9.6 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Kelch_4 PF13418.1 GAM19355.1 - 4.7e-13 48.6 1.2 1.2e-05 24.9 0.0 4.6 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM19355.1 - 9.3e-13 47.7 4.5 0.00018 21.5 0.0 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 GAM19355.1 - 2.6e-10 39.6 5.4 0.0019 17.6 0.1 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 GAM19355.1 - 3.1e-08 33.0 0.5 0.02 14.6 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 GAM19355.1 - 2.6e-07 30.6 2.3 0.0033 17.5 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM19355.1 - 0.00027 20.7 9.4 0.19 11.7 0.9 4.3 4 0 0 4 4 4 2 Kelch motif zf-CCCH_2 PF14608.1 GAM19356.1 - 0.0038 17.1 3.7 0.0067 16.3 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 GAM19356.1 - 0.069 12.8 4.7 0.12 12.0 3.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_2 PF12796.2 GAM19357.1 - 4.2e-08 33.4 8.4 1 9.7 0.4 7.9 3 2 0 4 4 4 2 Ankyrin repeats (3 copies) Coiled PF05710.7 GAM19358.1 - 0.0056 17.1 2.6 0.0073 16.7 1.8 1.2 1 0 0 1 1 1 1 Coiled coil DUF1183 PF06682.7 GAM19359.1 - 0.15 11.6 0.6 0.3 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Trypan_PARP PF05887.6 GAM19360.1 - 0.21 11.3 5.8 0.43 10.3 4.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.2 GAM19361.1 - 2.4e-16 59.8 0.1 0.0011 19.2 0.3 6.7 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19361.1 - 1.3e-07 31.1 8.8 12 6.4 0.0 10.1 10 2 2 12 12 12 2 Ankyrin repeat Ank_4 PF13637.1 GAM19361.1 - 8.5e-05 22.9 1.3 7 7.3 0.0 7.0 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19361.1 - 0.00014 21.4 0.1 0.7 9.8 0.0 6.0 6 0 0 6 6 6 1 Ankyrin repeat Inositol_P PF00459.20 GAM19362.1 - 1.2e-48 165.8 0.0 1.7e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1390 PF07150.6 GAM19363.1 - 0.12 11.7 0.2 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Dict-STAT-coil PF09267.5 GAM19364.1 - 4.1e-31 107.5 8.8 4.1e-31 107.5 6.1 5.0 4 2 2 6 6 6 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 GAM19364.1 - 0.00063 19.5 0.1 0.007 16.1 0.0 2.7 2 0 0 2 2 2 1 SH2 domain SRF-TF PF00319.13 GAM19365.1 - 4.6e-08 32.1 0.2 1.2e-07 30.8 0.1 1.8 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PIF1 PF05970.9 GAM19367.1 - 1.8e-55 188.3 0.3 6.8e-44 150.2 0.0 3.0 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 GAM19367.1 - 4.9e-19 68.6 0.0 1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 GAM19367.1 - 9.6e-10 36.8 0.1 2.1e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 GAM19367.1 - 7.4e-07 29.3 0.0 2.1e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 GAM19367.1 - 2.7e-05 24.2 0.0 7.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 GAM19367.1 - 7.5e-05 22.4 4.2 0.065 12.8 0.3 3.2 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 GAM19367.1 - 0.00014 21.5 0.4 0.00031 20.4 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAM19367.1 - 0.00036 20.5 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 GAM19367.1 - 0.00044 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 GAM19367.1 - 0.0026 17.2 0.0 0.98 8.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 GAM19367.1 - 0.0026 16.9 0.0 0.0062 15.7 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.9 GAM19367.1 - 0.015 15.0 0.1 0.071 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAM19367.1 - 0.016 14.5 0.0 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 GAM19367.1 - 0.025 14.2 0.1 0.093 12.3 0.1 2.0 1 1 0 1 1 1 0 Helicase Viral_helicase1 PF01443.13 GAM19367.1 - 0.025 14.0 3.5 0.28 10.6 0.0 3.1 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 GAM19367.1 - 0.041 12.9 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RE_AccI PF09545.5 GAM19367.1 - 0.061 11.8 0.0 0.099 11.1 0.0 1.3 1 0 0 1 1 1 0 AccI restriction endonuclease AAA_33 PF13671.1 GAM19367.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAM19367.1 - 0.095 12.4 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 0 NTPase Iso_dh PF00180.15 GAM19368.1 - 5e-76 255.9 0.0 5.9e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SET PF00856.23 GAM19369.1 - 7.8e-11 42.5 0.0 2.6e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 GAM19369.1 - 1e-08 34.8 14.7 1e-08 34.8 10.2 2.7 2 1 0 2 2 2 1 MYND finger SET PF00856.23 GAM19370.1 - 5.8e-11 42.9 0.2 1.3e-10 41.7 0.1 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 GAM19370.1 - 5.9e-09 35.6 12.3 5.9e-09 35.6 8.5 3.2 4 1 0 4 4 4 1 MYND finger Hema_stalk PF08720.5 GAM19370.1 - 0.089 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk ArfGap PF01412.13 GAM19371.1 - 7.1e-29 99.9 0.4 7.1e-29 99.9 0.3 3.0 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf zf-B_box PF00643.19 GAM19371.1 - 0.48 10.3 3.3 0.83 9.5 2.3 1.3 1 0 0 1 1 1 0 B-box zinc finger Myotub-related PF06602.9 GAM19372.1 - 1.2e-119 399.2 0.0 2.4e-119 398.2 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ank_2 PF12796.2 GAM19372.1 - 2.3e-41 140.0 0.2 2.7e-11 43.6 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM19372.1 - 1.8e-23 82.4 3.3 6.4e-08 32.8 0.0 5.7 4 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM19372.1 - 1.5e-22 78.1 0.0 0.0011 18.6 0.0 6.4 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAM19372.1 - 1.3e-19 69.7 0.1 1.7e-07 31.2 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19372.1 - 3.2e-13 48.5 9.5 0.0071 16.4 0.0 7.0 8 0 0 8 8 8 4 Ankyrin repeat GRAM PF02893.15 GAM19372.1 - 5.7e-05 22.5 0.0 0.00018 20.9 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 GAM19372.1 - 0.022 15.0 0.1 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 Tyrosine phosphatase family Pkinase PF00069.20 GAM19373.1 - 4e-74 249.0 0.0 5.2e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19373.1 - 5.9e-33 114.0 0.0 1.2e-32 113.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19373.1 - 9.8e-07 28.0 0.0 4.3e-05 22.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAM19373.1 - 0.022 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family AMP-binding PF00501.23 GAM19374.1 - 1.4e-85 287.2 0.0 2.4e-85 286.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 GAM19375.1 - 2.8e-61 206.9 0.1 5.7e-61 205.9 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19375.1 - 7.4e-48 162.8 0.1 1.2e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.1 GAM19375.1 - 2.5e-06 26.9 0.0 4.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM19375.1 - 2.6e-05 23.5 0.0 4.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM19375.1 - 0.00011 21.6 0.0 0.00032 20.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain RIO1 PF01163.17 GAM19375.1 - 0.0023 17.2 1.7 0.0028 17.0 0.1 1.9 2 1 0 2 2 2 1 RIO1 family APH PF01636.18 GAM19375.1 - 0.0032 17.2 0.0 0.093 12.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM19375.1 - 0.016 14.1 0.1 0.15 11.0 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.9 GAM19375.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Coiled PF05710.7 GAM19376.1 - 0.036 14.5 10.3 0.043 14.2 7.1 1.1 1 0 0 1 1 1 0 Coiled coil Bac_surface_Ag PF01103.18 GAM19377.1 - 6.8e-10 38.9 9.5 9.9e-10 38.3 6.6 1.3 1 0 0 1 1 1 1 Surface antigen Syja_N PF02383.13 GAM19378.1 - 7.2e-84 281.2 0.1 1e-83 280.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Nucleoplasmin PF03066.10 GAM19378.1 - 0.35 10.3 4.2 0.68 9.4 2.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 GAM19378.1 - 1.9 8.3 12.4 4.1 7.1 8.6 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RB_A PF01858.12 GAM19379.1 - 1.2e-26 93.6 0.1 1.2e-26 93.6 0.0 2.4 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain DUF3452 PF11934.3 GAM19379.1 - 3.1e-24 84.8 0.0 3.1e-24 84.8 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3452) RB_B PF01857.15 GAM19379.1 - 1.1e-06 28.1 7.2 1.3e-06 27.9 1.8 3.0 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Methyltransf_11 PF08241.7 GAM19380.1 - 8.7e-18 64.6 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM19380.1 - 1.1e-17 64.0 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM19380.1 - 7.1e-16 58.0 0.0 3e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM19380.1 - 2.6e-11 43.7 0.0 5.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM19380.1 - 1.1e-10 42.0 0.0 7e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM19380.1 - 3.2e-10 39.9 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM19380.1 - 2.2e-09 37.6 0.0 3.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM19380.1 - 7.4e-07 28.6 0.0 1.4e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 GAM19380.1 - 4.2e-06 26.0 0.0 6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Cons_hypoth95 PF03602.10 GAM19380.1 - 6.4e-05 22.4 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 GAM19380.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAM19380.1 - 0.0032 16.8 0.1 0.016 14.5 0.1 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.6 GAM19380.1 - 0.0047 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PCMT PF01135.14 GAM19380.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 GAM19380.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 GAM19380.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 GAM19380.1 - 0.02 14.0 0.0 0.1 11.6 0.0 1.9 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 GAM19380.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 GAM19380.1 - 0.079 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G GCV_T PF01571.16 GAM19383.1 - 3.8e-15 55.8 0.0 8.5e-15 54.6 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 GAM19383.1 - 0.013 15.5 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain LIME1 PF15332.1 GAM19383.1 - 0.044 13.0 0.1 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Pkinase PF00069.20 GAM19384.1 - 3.4e-58 196.8 0.0 5.4e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19384.1 - 3.8e-44 150.7 0.0 5.6e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM19384.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCHC PF00098.18 GAM19385.1 - 9.3e-19 66.3 33.3 1.1e-06 28.3 1.0 4.4 4 0 0 4 4 4 4 Zinc knuckle CMS1 PF14617.1 GAM19385.1 - 7.2e-15 54.7 3.1 7.2e-15 54.7 2.2 2.8 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit zf-CCHC_4 PF14392.1 GAM19385.1 - 0.012 15.2 23.8 0.15 11.7 0.5 4.5 4 0 0 4 4 4 0 Zinc knuckle DEAD PF00270.24 GAM19385.1 - 0.038 13.4 0.0 0.12 11.8 0.0 1.6 1 1 1 2 2 2 0 DEAD/DEAH box helicase zf-CCHC_6 PF15288.1 GAM19385.1 - 0.75 9.5 25.3 0.26 10.9 0.4 4.4 2 2 2 4 4 4 0 Zinc knuckle zf-RING_2 PF13639.1 GAM19386.1 - 1.6e-13 50.2 3.5 3e-13 49.3 2.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM19386.1 - 7.6e-11 41.9 1.6 1.5e-10 40.9 0.7 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAM19386.1 - 3.5e-07 29.7 4.6 7.8e-07 28.6 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM19386.1 - 8.9e-07 28.5 2.4 1.8e-06 27.5 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM19386.1 - 1.2e-06 28.4 7.4 2.4e-06 27.4 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM19386.1 - 9.5e-06 25.3 0.4 2.2e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 GAM19386.1 - 3.3e-05 23.4 2.3 5.7e-05 22.7 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 GAM19386.1 - 0.00027 20.3 0.6 0.00082 18.8 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 GAM19386.1 - 0.001 19.0 4.1 0.0019 18.1 2.9 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 GAM19386.1 - 0.0015 18.4 2.8 0.0032 17.3 2.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 GAM19386.1 - 0.008 15.8 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 GAM19386.1 - 0.048 13.3 4.3 0.11 12.2 3.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAM19386.1 - 3.9 7.4 8.2 44 4.0 5.8 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Gelsolin PF00626.17 GAM19387.1 - 0.00023 20.7 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Sec23_trunk PF04811.10 GAM19388.1 - 2.2e-13 50.1 0.4 7.9e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 GAM19388.1 - 4.6e-10 39.8 0.3 3.8e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM19388.1 - 7.6e-09 34.9 3.2 1.7e-08 33.9 2.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger FYVE_2 PF02318.11 GAM19388.1 - 0.11 12.3 0.2 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Palm_thioest PF02089.10 GAM19389.1 - 1.5e-112 375.0 0.0 1.8e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 GAM19389.1 - 0.0027 17.0 0.0 0.0098 15.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.15 GAM19389.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RasGEF PF00617.14 GAM19390.1 - 7.2e-53 179.1 0.2 7.2e-53 179.1 0.2 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAM19390.1 - 0.00044 20.3 2.4 0.0012 18.9 0.6 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif GCFC PF07842.7 GAM19391.1 - 2.8e-22 79.3 4.7 6.1e-20 71.7 3.3 3.3 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein LysM PF01476.15 GAM19392.1 - 0.0001 22.1 0.0 0.00029 20.6 0.0 1.9 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.1 GAM19392.1 - 0.00035 20.0 0.0 0.00097 18.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Ribosomal_L35Ae PF01247.13 GAM19392.1 - 0.18 11.5 0.8 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L35Ae HHH_3 PF12836.2 GAM19394.1 - 9.5e-08 31.8 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF655 PF04919.7 GAM19394.1 - 5.4e-05 22.9 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF655) HHH_6 PF14579.1 GAM19394.1 - 0.0025 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif RE_LlaMI PF09562.5 GAM19394.1 - 0.025 13.7 0.5 0.04 13.0 0.1 1.5 2 0 0 2 2 2 0 LlaMI restriction endonuclease T2SK PF03934.8 GAM19394.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Methyltransf_11 PF08241.7 GAM19396.1 - 4.1e-20 72.0 0.0 6.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM19396.1 - 9.6e-17 60.8 0.0 5.7e-16 58.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM19396.1 - 3.6e-14 52.9 0.0 7.3e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM19396.1 - 4.1e-12 46.6 0.0 2.5e-11 44.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM19396.1 - 3.4e-10 39.7 0.0 5.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM19396.1 - 8.2e-10 39.0 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM19396.1 - 7.5e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM19396.1 - 0.0001 22.3 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM19396.1 - 0.0046 16.3 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 GAM19396.1 - 0.044 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 GAM19396.1 - 0.05 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase FAD_binding_3 PF01494.14 GAM19397.1 - 1.6e-88 297.1 0.0 2.3e-88 296.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM19397.1 - 3.1e-10 39.5 0.3 2.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM19397.1 - 9e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM19397.1 - 2.6e-05 23.2 0.5 7.8e-05 21.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM19397.1 - 0.00013 21.9 0.0 0.0008 19.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 GAM19397.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Thi4 PF01946.12 GAM19397.1 - 0.013 14.5 0.0 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Cytomega_gL PF01801.11 GAM19397.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L UDPG_MGDP_dh_N PF03721.9 GAM19397.1 - 0.023 14.0 0.1 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 GAM19397.1 - 0.025 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM19397.1 - 0.034 14.2 0.1 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM19397.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 GAM19397.1 - 0.06 11.9 0.0 0.094 11.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 GAM19397.1 - 0.077 12.0 0.2 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM19397.1 - 0.11 11.3 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 GAM19397.1 - 0.13 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NTF2 PF02136.15 GAM19398.1 - 5.4e-22 78.3 0.0 6e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 GAM19398.1 - 0.012 15.3 0.1 0.014 15.1 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Iso_dh PF00180.15 GAM19399.1 - 1.1e-57 195.5 0.1 1.5e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AstE_AspA PF04952.9 GAM19400.1 - 2.1e-44 151.5 0.0 1.8e-43 148.5 0.0 1.9 1 1 1 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.19 GAM19400.1 - 0.0051 16.4 0.0 0.071 12.7 0.0 2.3 1 1 0 1 1 1 1 Zinc carboxypeptidase Hist_deacetyl PF00850.14 GAM19401.1 - 2.5e-71 240.5 0.5 2.5e-71 240.5 0.3 2.5 2 0 0 2 2 2 1 Histone deacetylase domain DIL PF01843.14 GAM19402.1 - 3.5e-25 87.9 0.7 2.4e-24 85.2 0.5 2.6 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.4 GAM19402.1 - 4.3e-25 87.8 3.7 4.3e-25 87.8 2.5 2.3 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Reo_sigmaC PF04582.7 GAM19402.1 - 4.8e-08 32.5 61.2 0.01 15.0 9.6 5.8 2 1 2 5 5 5 5 Reovirus sigma C capsid protein Filament PF00038.16 GAM19402.1 - 1.4e-05 24.6 125.6 1.7e-05 24.4 26.5 5.6 1 1 3 5 5 5 2 Intermediate filament protein Myosin_tail_1 PF01576.14 GAM19402.1 - 4.4e-05 21.4 141.2 0.32 8.6 34.0 5.3 1 1 4 5 5 5 4 Myosin tail IncA PF04156.9 GAM19402.1 - 5.8e-05 22.7 137.9 0.042 13.4 14.2 8.2 1 1 7 8 8 8 5 IncA protein AAA_13 PF13166.1 GAM19402.1 - 0.0013 17.2 26.1 0.0013 17.2 18.1 5.1 1 1 4 5 5 5 4 AAA domain FliJ PF02050.11 GAM19402.1 - 0.0025 17.8 12.4 0.0025 17.8 8.6 8.5 2 2 6 8 8 7 2 Flagellar FliJ protein Laminin_II PF06009.7 GAM19402.1 - 0.0028 17.4 9.3 0.0028 17.4 6.4 8.3 1 1 7 8 8 7 1 Laminin Domain II TMF_DNA_bd PF12329.3 GAM19402.1 - 0.0049 16.6 9.4 0.0049 16.6 6.5 12.4 5 3 7 12 12 12 3 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 GAM19402.1 - 0.0053 16.1 10.9 0.0053 16.1 7.6 8.4 1 1 7 9 9 8 2 Protein of unknown function (DUF2968) DUF904 PF06005.7 GAM19402.1 - 0.0061 16.8 5.1 0.0061 16.8 3.5 11.8 3 1 6 9 9 6 1 Protein of unknown function (DUF904) ADIP PF11559.3 GAM19402.1 - 5.2 6.9 141.7 0.34 10.8 7.1 9.0 1 1 7 8 8 7 0 Afadin- and alpha -actinin-Binding ACOX PF01756.14 GAM19403.1 - 4.1e-17 62.1 0.0 4.9e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Acyl-CoA oxidase GSH-S_ATP PF02955.11 GAM19403.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Glyco_hydro_18 PF00704.23 GAM19403.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 NAD_binding_11 PF14833.1 GAM19403.1 - 0.13 12.3 0.0 0.45 10.5 0.0 1.8 1 1 1 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Acyl-CoA_dh_M PF02770.14 GAM19404.1 - 1.4e-06 27.6 0.0 3.9e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM19404.1 - 1.6e-06 28.2 0.0 5.4e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 GAM19404.1 - 0.015 15.6 0.2 0.042 14.1 0.0 1.9 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal MBOAT PF03062.14 GAM19405.1 - 2.5e-23 82.7 24.6 4.3e-23 81.9 17.1 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAM19405.1 - 0.00063 19.7 9.7 0.0017 18.4 6.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Sigma_reg_N PF13800.1 GAM19405.1 - 0.9 9.6 6.5 9.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF3552 PF12072.3 GAM19405.1 - 1.5 7.9 9.9 2.4 7.3 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Ank_2 PF12796.2 GAM19406.1 - 1e-11 44.9 10.4 0.011 16.0 0.3 8.8 3 3 3 7 7 7 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM19406.1 - 1.6e-09 37.6 3.8 7.1 7.0 0.0 8.2 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19406.1 - 9.4e-08 31.5 8.5 16 6.1 0.0 11.6 14 0 0 14 14 14 1 Ankyrin repeat Ank_4 PF13637.1 GAM19406.1 - 8e-07 29.4 5.3 0.23 12.0 0.0 7.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM19406.1 - 0.00024 20.7 0.3 52 3.9 0.0 6.5 6 0 0 6 6 6 0 Ankyrin repeat LIM PF00412.17 GAM19407.1 - 7.3e-24 83.6 23.0 1e-12 47.9 3.5 3.2 3 0 0 3 3 3 2 LIM domain DZR PF12773.2 GAM19407.1 - 0.67 9.8 20.3 1.5e+04 -4.7 14.0 3.6 1 1 0 1 1 1 0 Double zinc ribbon PHF5 PF03660.9 GAM19407.1 - 1.1 9.3 6.9 0.24 11.4 2.0 2.0 1 1 0 1 1 1 0 PHF5-like protein PRK PF00485.13 GAM19408.1 - 1.7e-16 60.3 3.2 1.5e-14 54.0 2.2 2.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.16 GAM19408.1 - 1.1e-13 51.2 0.0 2.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 CYTH domain AAA_17 PF13207.1 GAM19408.1 - 2e-06 28.6 0.1 5.6e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM19408.1 - 5.2e-05 23.5 0.2 0.00014 22.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM19408.1 - 0.0039 16.3 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 GAM19408.1 - 0.0053 15.6 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 GAM19408.1 - 0.0061 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 GAM19408.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 GAM19408.1 - 0.023 14.9 0.0 0.071 13.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter CoaE PF01121.15 GAM19408.1 - 0.042 13.2 0.1 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 Dephospho-CoA kinase Glycos_transf_1 PF00534.15 GAM19408.1 - 0.048 13.0 0.0 0.93 8.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Homeobox PF00046.24 GAM19408.1 - 0.062 12.9 0.0 0.23 11.0 0.0 2.0 1 0 0 1 1 1 0 Homeobox domain UPF0079 PF02367.12 GAM19408.1 - 0.078 12.6 0.4 0.8 9.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 GST_C PF00043.20 GAM19409.1 - 2e-11 43.6 0.0 3.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM19409.1 - 1.6e-10 40.8 0.0 2.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM19409.1 - 5.1e-10 39.4 0.0 1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM19409.1 - 1.4e-08 34.7 0.0 3.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM19409.1 - 3.3e-08 33.2 0.0 7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM19409.1 - 5.3e-08 33.2 0.0 7.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 GAM19409.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain RasGEF PF00617.14 GAM19410.1 - 1.1e-56 191.5 0.0 2e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM19410.1 - 8.7e-20 70.7 0.4 2.3e-19 69.4 0.3 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif IncA PF04156.9 GAM19410.1 - 0.22 11.0 5.4 0.99 8.9 3.7 2.1 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 GAM19410.1 - 0.39 11.0 7.2 0.056 13.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 GAM19410.1 - 1 8.9 8.9 0.059 12.8 1.2 2.7 3 0 0 3 3 3 0 Septum formation initiator GSH_synth_ATP PF03917.12 GAM19411.1 - 7.5e-122 406.4 0.2 9.1e-122 406.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 GAM19411.1 - 6.8e-39 132.1 1.0 8.9e-37 125.3 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic glutathione synthase IMS_C PF11799.3 GAM19411.1 - 0.031 14.2 0.0 0.2 11.5 0.0 2.3 2 1 0 2 2 2 0 impB/mucB/samB family C-terminal domain Inhibitor_I24 PF10465.4 GAM19411.1 - 0.064 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 PinA peptidase inhibitor DUF1043 PF06295.7 GAM19411.1 - 0.74 9.4 4.9 1.4 8.5 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1043) zf-B_box PF00643.19 GAM19412.1 - 9.1e-06 25.4 4.4 9.1e-06 25.4 3.1 1.7 2 0 0 2 2 2 1 B-box zinc finger IncA PF04156.9 GAM19412.1 - 0.00021 20.9 0.5 0.00044 19.8 0.2 1.7 1 1 0 1 1 1 1 IncA protein Colipase-like PF15083.1 GAM19412.1 - 0.03 14.2 1.3 0.085 12.8 0.9 1.8 1 0 0 1 1 1 0 Colipase-like YPEB PF14620.1 GAM19412.1 - 0.03 13.3 4.2 0.45 9.4 0.1 2.1 2 0 0 2 2 2 0 YpeB sporulation Apolipoprotein PF01442.13 GAM19412.1 - 0.031 13.7 0.5 0.031 13.7 0.4 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 GAM19412.1 - 0.057 13.2 2.6 0.048 13.4 0.5 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_15 PF12324.3 GAM19412.1 - 0.073 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase DUF1664 PF07889.7 GAM19412.1 - 0.49 10.2 7.0 1.6 8.5 1.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3461 PF11944.3 GAM19412.1 - 0.56 10.0 5.2 0.17 11.6 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Cep57_MT_bd PF06657.8 GAM19412.1 - 0.72 9.8 5.7 0.31 11.0 1.3 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 zf-B_box PF00643.19 GAM19413.1 - 1.7e-09 37.4 1.4 3.9e-09 36.2 1.0 1.6 1 0 0 1 1 1 1 B-box zinc finger zf-B_box PF00643.19 GAM19414.1 - 4.5e-10 39.2 3.6 8.2e-10 38.4 2.5 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.1 GAM19414.1 - 2.4e-08 33.8 7.9 0.032 14.4 0.1 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 GAM19414.1 - 1.1e-05 25.4 5.0 0.41 10.8 0.1 4.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM19414.1 - 2.1e-05 23.9 6.1 0.07 12.6 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM19414.1 - 5e-05 22.9 3.3 0.024 14.4 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM19414.1 - 0.95 9.4 9.2 10 6.2 1.6 3.7 4 0 0 4 4 4 0 Kelch motif Abhydrolase_6 PF12697.2 GAM19415.1 - 9.4e-35 120.5 0.0 1.2e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM19415.1 - 4.5e-20 71.8 0.0 9e-20 70.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM19415.1 - 7e-17 61.7 0.3 1.1e-14 54.5 0.2 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM19415.1 - 3.3e-07 30.0 0.0 7.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 GAM19415.1 - 9.5e-07 28.3 0.1 0.00016 21.0 0.0 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAM19415.1 - 3.2e-05 23.4 0.0 0.0093 15.4 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase UPF0227 PF05728.7 GAM19415.1 - 0.00041 20.1 0.0 0.079 12.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Ndr PF03096.9 GAM19415.1 - 0.00086 17.8 0.0 0.0051 15.3 0.0 2.0 2 0 0 2 2 2 1 Ndr family DUF2048 PF09752.4 GAM19415.1 - 0.0033 16.3 0.1 1 8.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 GAM19415.1 - 0.01 15.2 0.0 0.045 13.1 0.0 2.0 2 0 0 2 2 2 0 Putative esterase FSH1 PF03959.8 GAM19415.1 - 0.016 14.6 0.1 0.12 11.8 0.1 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PGAP1 PF07819.8 GAM19415.1 - 0.019 14.5 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein LIP PF03583.9 GAM19415.1 - 0.03 13.5 2.0 3 6.9 0.3 2.6 2 1 0 2 2 2 0 Secretory lipase Lipase_3 PF01764.20 GAM19415.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 GAM19415.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CTNNBL PF08216.6 GAM19417.1 - 8.3e-34 115.4 1.3 8.3e-34 115.4 0.9 2.9 3 1 1 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 GAM19417.1 - 0.023 14.5 0.1 5.2 7.0 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Myb_DNA-binding PF00249.26 GAM19418.1 - 4.5e-28 97.0 10.7 2.2e-13 49.9 0.5 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM19418.1 - 6e-27 93.5 8.4 5.5e-15 55.2 0.2 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 GAM19418.1 - 0.0039 17.2 14.1 0.058 13.5 0.9 3.7 2 1 1 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 GAM19418.1 - 2.7 8.2 9.1 7.2 6.8 0.2 3.9 3 2 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase PF00069.20 GAM19419.1 - 4.4e-70 235.7 0.0 6.9e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19419.1 - 9.8e-56 188.6 0.0 1.6e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19419.1 - 1.2e-06 27.7 0.0 6.9e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like PBD PF00786.23 GAM19419.1 - 3e-05 24.3 0.2 0.00018 21.8 0.1 2.5 1 0 0 1 1 1 1 P21-Rho-binding domain RIO1 PF01163.17 GAM19419.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family DUF4456 PF14644.1 GAM19419.1 - 0.022 13.9 0.5 0.041 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Tup_N PF08581.5 GAM19419.1 - 0.11 12.6 0.3 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Tup N-terminal Band_7_1 PF13421.1 GAM19419.1 - 0.13 11.7 0.4 0.3 10.5 0.3 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Fez1 PF06818.10 GAM19420.1 - 0.001 19.1 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 Fez1 Ly49 PF08391.5 GAM19420.1 - 0.013 15.6 0.8 0.018 15.1 0.6 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region APG6 PF04111.7 GAM19420.1 - 0.23 10.4 2.3 0.26 10.3 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF288 PF03385.12 GAM19420.1 - 0.23 9.8 1.1 0.28 9.6 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF288 PGC7_Stella PF15549.1 GAM19420.1 - 0.32 10.9 5.9 0.4 10.6 4.1 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF4337 PF14235.1 GAM19420.1 - 0.34 10.7 2.5 0.55 10.0 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Hamartin PF04388.7 GAM19420.1 - 0.65 8.6 4.6 0.68 8.5 3.2 1.0 1 0 0 1 1 1 0 Hamartin protein zf-LYAR PF08790.6 GAM19421.1 - 4.5e-06 26.2 0.3 1.2e-05 24.9 0.2 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger BUD22 PF09073.5 GAM19421.1 - 0.045 12.8 63.3 0.058 12.4 43.9 1.1 1 0 0 1 1 1 0 BUD22 DDE_Tnp_1_7 PF13843.1 GAM19424.1 - 3.5e-16 59.1 0.9 5.9e-16 58.4 0.6 1.3 1 0 0 1 1 1 1 Transposase IS4 CDC45 PF02724.9 GAM19424.1 - 0.046 11.7 33.8 0.29 9.1 10.0 2.2 2 0 0 2 2 2 0 CDC45-like protein TFIIA PF03153.8 GAM19424.1 - 0.047 13.5 33.2 0.58 9.9 3.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 GAM19424.1 - 0.11 10.3 46.2 0.53 8.1 16.6 2.1 2 0 0 2 2 2 0 Nop14-like family DUF1510 PF07423.6 GAM19424.1 - 0.38 10.0 31.8 0.15 11.4 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Daxx PF03344.10 GAM19424.1 - 0.56 8.6 41.2 0.52 8.7 14.4 2.1 2 0 0 2 2 2 0 Daxx Family Paf1 PF03985.8 GAM19424.1 - 1.7 7.3 28.3 2.6 6.6 7.6 2.5 2 0 0 2 2 2 0 Paf1 Pox_Ag35 PF03286.9 GAM19424.1 - 1.7 8.1 26.4 0.68 9.4 5.3 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-T PF15511.1 GAM19424.1 - 5.4 6.1 27.0 1.6 7.8 7.3 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Cnd1 PF12717.2 GAM19425.1 - 3e-49 167.2 5.4 3e-49 167.2 3.8 6.4 6 2 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 GAM19425.1 - 1.7e-34 118.8 1.5 1.7e-34 118.8 1.0 3.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 GAM19425.1 - 2.9e-06 27.4 0.0 2.2 8.6 0.0 5.3 4 3 0 4 4 4 2 HEAT repeats HEAT PF02985.17 GAM19425.1 - 4.5e-05 23.1 0.3 2.5 8.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 GAM19425.1 - 0.0031 17.9 0.3 14 6.3 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat U3snoRNP10 PF12397.3 GAM19425.1 - 0.13 12.2 0.0 0.13 12.2 0.0 4.0 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 Mito_fiss_reg PF05308.6 GAM19426.1 - 3.3 7.0 8.7 1 8.6 1.9 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator Ank_3 PF13606.1 GAM19428.1 - 0.00026 20.9 2.0 80 3.9 0.0 7.3 7 1 1 8 8 8 0 Ankyrin repeat INT_SG_DDX_CT_C PF15300.1 GAM19428.1 - 0.026 13.9 0.0 0.1 12.0 0.0 2.1 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Ank_5 PF13857.1 GAM19428.1 - 0.062 13.5 0.3 32 4.9 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ribosomal_L27e PF01777.13 GAM19429.1 - 1.5e-26 92.3 5.3 2.4e-26 91.6 3.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 GAM19429.1 - 3.9e-05 23.2 0.1 0.00024 20.7 0.0 2.3 2 0 0 2 2 2 1 KOW motif Asp_protease PF09668.5 GAM19430.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF2428 PF10350.4 GAM19431.1 - 0.13 11.3 1.7 1.1 8.1 0.0 2.2 1 1 1 2 2 2 0 Putative death-receptor fusion protein (DUF2428) TMEM154 PF15102.1 GAM19432.1 - 1.6 8.4 19.4 3.1 7.4 13.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF1180 PF06679.7 GAM19432.1 - 5.2 6.9 11.0 5.2 6.9 6.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TFIIE_beta PF02186.10 GAM19433.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain E2F_TDP PF02319.15 GAM19433.1 - 0.079 12.5 0.0 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain TPR_11 PF13414.1 GAM19434.1 - 1.3e-45 152.9 24.5 4.6e-13 48.6 0.4 7.8 4 3 5 9 9 9 7 TPR repeat TPR_2 PF07719.12 GAM19434.1 - 2.6e-45 148.6 17.9 3.3e-08 32.8 0.1 10.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.23 GAM19434.1 - 3e-45 150.0 14.1 5.2e-10 38.4 0.1 10.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 GAM19434.1 - 3e-32 107.9 9.2 4.1e-05 23.0 0.0 9.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAM19434.1 - 8.5e-31 105.7 14.2 2.1e-05 24.3 0.2 8.2 4 2 2 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAM19434.1 - 3.4e-28 97.6 1.2 1.7e-09 38.0 0.0 7.3 6 1 0 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM19434.1 - 2.4e-27 94.8 18.8 1.4e-11 44.3 0.5 6.3 3 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 GAM19434.1 - 6.7e-25 87.2 10.4 0.0017 18.6 0.5 8.1 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAM19434.1 - 2.6e-23 80.3 1.7 0.0052 17.3 0.0 10.7 4 2 7 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM19434.1 - 1.2e-18 65.7 8.1 9.1e-05 22.3 0.1 8.6 9 1 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM19434.1 - 1.3e-17 62.9 7.0 0.19 12.2 0.0 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM19434.1 - 2.7e-11 43.1 3.7 0.015 15.1 0.0 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM19434.1 - 7e-11 41.6 4.5 0.026 14.4 0.1 7.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM19434.1 - 7.2e-11 41.0 12.9 1 9.3 0.0 9.6 11 0 0 11 11 10 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM19434.1 - 1.7e-05 24.5 8.9 0.017 15.0 0.1 6.6 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 GAM19434.1 - 0.001 18.6 4.0 0.34 10.3 0.1 3.7 3 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) Coatomer_E PF04733.9 GAM19434.1 - 0.0081 15.3 1.2 1.9 7.5 0.0 2.7 2 1 0 2 2 2 2 Coatomer epsilon subunit MIT PF04212.13 GAM19434.1 - 0.0098 15.7 0.9 2.2 8.2 0.0 3.8 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain FAT PF02259.18 GAM19434.1 - 0.097 11.6 0.0 0.097 11.6 0.0 3.9 2 1 1 4 4 4 0 FAT domain NARP1 PF12569.3 GAM19434.1 - 0.21 10.2 12.0 0.048 12.4 0.1 3.4 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 SpoU_methylase PF00588.14 GAM19435.1 - 1.3e-29 102.9 0.0 1.9e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Oxidored_nitro PF00148.14 GAM19435.1 - 0.03 12.9 0.0 0.037 12.6 0.0 1.3 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase BaffR-Tall_bind PF09256.5 GAM19435.1 - 0.094 12.3 0.0 33 4.1 0.0 3.3 3 0 0 3 3 3 0 BAFF-R, TALL-1 binding Eapp_C PF10238.4 GAM19436.1 - 1e-40 138.7 14.7 1e-40 138.7 10.2 2.2 2 0 0 2 2 2 1 E2F-associated phosphoprotein IBR PF01485.16 GAM19436.1 - 0.02 14.7 2.2 0.12 12.2 0.3 2.3 2 0 0 2 2 2 0 IBR domain Yippee-Mis18 PF03226.9 GAM19436.1 - 0.34 10.9 7.9 1.1 9.2 5.5 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C3HC4_2 PF13923.1 GAM19437.1 - 2.6e-09 36.9 11.8 4.7e-09 36.1 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 GAM19437.1 - 5e-09 35.6 1.1 5e-09 35.6 0.8 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 GAM19437.1 - 7.1e-09 35.2 8.1 1.3e-08 34.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM19437.1 - 2.6e-07 30.3 9.4 4.6e-07 29.5 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM19437.1 - 4.4e-07 29.5 12.8 8.5e-07 28.6 8.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM19437.1 - 3.2e-06 26.6 12.6 8e-06 25.4 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM19437.1 - 0.0011 18.5 6.3 0.0033 17.1 3.6 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAM19437.1 - 0.0062 16.3 9.2 0.016 15.0 6.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Herpes_TK PF00693.13 GAM19437.1 - 0.17 11.0 0.1 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus zf-P11 PF03854.9 GAM19437.1 - 0.39 10.2 5.6 0.78 9.2 3.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.3 GAM19437.1 - 0.42 10.1 6.4 0.93 9.0 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 GAM19437.1 - 0.9 9.6 9.7 3.5 7.7 6.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger FNIP PF05725.7 GAM19438.1 - 1.4e-40 136.9 21.7 1.6e-10 40.7 0.7 7.0 4 2 2 7 7 7 6 FNIP Repeat DUF1769 PF08588.5 GAM19438.1 - 0.00053 19.8 4.7 2.5 8.1 0.0 5.1 3 1 2 5 5 5 2 Protein of unknown function (DUF1769) Mt_ATP-synt_D PF05873.7 GAM19439.1 - 0.0058 16.2 0.2 0.0063 16.1 0.1 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF1981 PF09324.5 GAM19439.1 - 0.026 14.0 0.3 0.043 13.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1981) DUF1690 PF07956.6 GAM19439.1 - 0.037 14.0 3.3 0.06 13.3 2.3 1.3 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Med29 PF11568.3 GAM19439.1 - 0.042 13.8 1.3 0.054 13.5 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 CHCH PF06747.8 GAM19439.1 - 0.058 13.3 1.5 0.11 12.4 1.0 1.4 1 0 0 1 1 1 0 CHCH domain GCK PF07802.6 GAM19439.1 - 0.62 10.2 3.8 3.4 7.8 1.4 2.4 2 1 1 3 3 3 0 GCK domain GTP_EFTU PF00009.22 GAM19441.1 - 5.4e-58 195.5 0.1 7.6e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM19441.1 - 1.5e-33 114.8 0.2 6.1e-33 112.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM19441.1 - 1.7e-17 63.2 0.5 4.3e-17 61.9 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM19441.1 - 5.6e-05 23.0 0.1 0.00019 21.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAM19441.1 - 5.7e-05 22.6 0.2 0.00017 21.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.7 GAM19441.1 - 0.0043 16.2 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM19441.1 - 0.04 14.3 0.3 0.37 11.3 0.2 2.3 1 1 0 1 1 1 0 Miro-like protein Ank_2 PF12796.2 GAM19442.1 - 5.5e-18 65.1 10.2 0.0069 16.7 0.0 9.4 8 2 1 9 9 9 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM19442.1 - 4e-06 27.1 11.4 6.5 7.3 0.0 10.4 10 2 1 11 11 11 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19442.1 - 8.1e-06 25.6 23.5 0.053 13.7 0.0 13.1 16 0 0 16 16 16 1 Ankyrin repeat Ank_5 PF13857.1 GAM19442.1 - 0.00046 20.3 9.6 1.7 8.9 0.0 7.9 8 1 0 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19442.1 - 0.0093 15.7 14.1 16 5.5 0.0 10.7 16 0 0 16 16 16 1 Ankyrin repeat Mito_carr PF00153.22 GAM19443.1 - 2.7e-69 228.9 2.0 4.8e-24 83.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DAO PF01266.19 GAM19444.1 - 4.4e-05 22.5 3.8 4.6e-05 22.4 0.5 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 GAM19444.1 - 0.00028 20.1 0.8 0.073 12.2 0.2 2.4 1 1 1 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.9 GAM19444.1 - 0.00093 19.1 0.0 0.002 18.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM19444.1 - 0.0034 16.5 0.1 0.0064 15.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 GAM19444.1 - 0.0083 15.0 0.3 0.016 14.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 GAM19444.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 GAM19444.1 - 0.037 13.0 0.0 0.076 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 GAM19444.1 - 0.04 12.8 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 GAM19444.1 - 0.062 13.3 0.2 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM19444.1 - 0.074 13.4 0.2 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM19444.1 - 0.085 12.6 0.2 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 GAM19444.1 - 0.092 12.7 0.2 0.32 11.0 0.2 1.9 1 0 0 1 1 1 0 TrkA-N domain Myb_DNA-binding PF00249.26 GAM19445.1 - 2.2e-28 98.0 11.6 8e-14 51.4 0.2 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM19445.1 - 6.2e-25 87.0 11.6 2.2e-16 59.6 0.7 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Chal_sti_synt_N PF00195.14 GAM19445.1 - 0.012 14.8 0.1 0.019 14.2 0.1 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain SLIDE PF09111.5 GAM19445.1 - 0.059 13.1 0.3 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 SLIDE Ssu72 PF04722.8 GAM19445.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Ssu72-like protein MADF_DNA_bdg PF10545.4 GAM19445.1 - 0.64 10.2 7.0 0.8 9.9 0.7 2.5 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.1 GAM19445.1 - 0.65 9.9 8.9 29 4.6 0.0 4.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 GAM19445.1 - 0.98 9.6 16.0 0.39 10.8 2.3 4.2 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain UQ_con PF00179.21 GAM19447.1 - 3.1e-41 140.0 0.1 5.8e-41 139.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.1 GAM19447.1 - 2.8e-17 63.3 0.0 5.9e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Prok-E2_B PF14461.1 GAM19447.1 - 3.5e-05 23.5 0.0 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B VWA PF00092.23 GAM19447.1 - 0.00036 20.2 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain UEV PF05743.8 GAM19447.1 - 0.0017 18.0 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 UEV domain Rad60-SLD PF11976.3 GAM19447.1 - 0.017 14.7 1.1 0.038 13.6 0.8 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Patatin PF01734.17 GAM19448.1 - 4.1e-17 62.8 0.5 1.1e-16 61.3 0.3 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase ALF PF03752.8 GAM19448.1 - 0.012 15.4 0.5 0.08 12.8 0.1 2.2 2 0 0 2 2 2 0 Short repeats of unknown function RRM_1 PF00076.17 GAM19449.1 - 2.5e-19 68.6 0.1 3.9e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19449.1 - 4.7e-14 52.1 0.0 7.7e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19449.1 - 6.7e-11 41.8 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM19449.1 - 0.0038 16.9 0.1 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 Usher PF00577.15 GAM19449.1 - 0.0055 15.4 5.6 0.0075 15.0 3.9 1.1 1 0 0 1 1 1 1 Outer membrane usher protein Pro_isomerase PF00160.16 GAM19450.1 - 4.3e-41 140.6 0.1 7.6e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 GAM19450.1 - 2.6e-14 52.5 0.0 5.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19450.1 - 7e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19450.1 - 5.8e-08 32.4 0.1 1.6e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM19450.1 - 0.028 14.1 0.1 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SURF2 PF05477.6 GAM19451.1 - 2.6e-15 56.2 63.0 3.2e-14 52.6 43.7 2.5 1 1 0 1 1 1 1 Surfeit locus protein 2 (SURF2) Utp14 PF04615.8 GAM19451.1 - 0.076 11.1 44.2 0.081 11.0 30.6 1.1 1 0 0 1 1 1 0 Utp14 protein zf-C2H2_jaz PF12171.3 GAM19451.1 - 0.086 13.0 1.9 9.5 6.5 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DPM3 PF08285.6 GAM19452.1 - 7.2e-30 102.6 0.3 8e-30 102.5 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PIG-P PF08510.7 GAM19452.1 - 0.11 12.1 1.1 0.18 11.4 0.8 1.4 1 1 0 1 1 1 0 PIG-P FixP_N PF14715.1 GAM19452.1 - 1.5 8.2 3.4 6.8 6.1 0.2 2.3 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Pkinase PF00069.20 GAM19453.1 - 1.7e-46 158.4 0.0 1.5e-45 155.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19453.1 - 1.4e-25 89.8 0.0 2.7e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAM19453.1 - 0.053 12.3 0.2 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Kelch_4 PF13418.1 GAM19455.1 - 4.5e-07 29.5 1.0 0.033 13.9 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain zf-CCCH PF00642.19 GAM19455.1 - 0.00013 21.5 16.0 0.0058 16.2 0.4 3.5 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_6 PF13964.1 GAM19455.1 - 0.0003 20.8 0.8 0.48 10.6 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 GAM19455.1 - 0.0013 18.1 0.7 0.056 12.9 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 GAM19455.1 - 0.0058 16.3 0.6 0.32 10.8 0.0 3.2 3 0 0 3 3 3 1 Kelch motif AF0941-like PF14591.1 GAM19455.1 - 7 6.7 11.6 0.81 9.7 1.4 2.8 3 0 0 3 3 3 0 AF0941-like Kelch_4 PF13418.1 GAM19456.1 - 2.9e-13 49.3 2.1 1.5e-07 31.0 0.0 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM19456.1 - 9.2e-11 41.4 3.7 0.00017 21.6 0.0 4.9 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM19456.1 - 4.4e-06 26.7 0.2 0.064 13.4 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Baculo_PEP_C PF04513.7 GAM19456.1 - 0.00032 20.5 9.7 0.00032 20.5 6.7 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_1 PF01344.20 GAM19456.1 - 0.0052 16.3 0.0 0.0052 16.3 0.0 4.4 5 1 0 5 5 5 1 Kelch motif FliT PF05400.8 GAM19456.1 - 0.011 16.0 0.2 0.028 14.8 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Kelch_5 PF13854.1 GAM19456.1 - 0.045 13.7 7.9 2.2 8.3 0.1 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 GAM19456.1 - 0.05 13.3 0.6 18 5.3 0.0 3.7 4 0 0 4 4 4 0 Kelch motif DUF4111 PF13427.1 GAM19456.1 - 0.055 13.2 0.1 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUF3461 PF11944.3 GAM19456.1 - 0.12 12.1 4.5 0.045 13.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) FlgN PF05130.7 GAM19456.1 - 0.57 10.4 4.8 1.1 9.5 0.5 2.3 1 1 1 2 2 2 0 FlgN protein GMP_synt_C PF00958.17 GAM19456.1 - 2.7 7.7 4.7 32 4.3 0.5 3.4 2 2 2 4 4 4 0 GMP synthase C terminal domain Kelch_6 PF13964.1 GAM19457.1 - 2.4e-15 55.9 3.0 7.4e-06 25.9 0.0 4.7 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM19457.1 - 5.1e-12 45.3 2.4 1e-08 34.8 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM19457.1 - 2.4e-11 43.4 2.6 0.00047 20.2 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM19457.1 - 7.5e-11 41.4 1.0 3.7e-05 23.1 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM19457.1 - 2.9e-06 26.8 0.4 0.0025 17.5 0.0 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM19457.1 - 3.8e-05 23.5 6.7 0.009 15.9 0.0 4.4 4 0 0 4 4 4 2 Kelch motif AF0941-like PF14591.1 GAM19457.1 - 0.027 14.5 2.2 0.054 13.5 1.5 1.4 1 0 0 1 1 1 0 AF0941-like DUF2240 PF09999.4 GAM19457.1 - 0.15 11.5 0.6 0.28 10.6 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Snapin_Pallidin PF14712.1 GAM19457.1 - 0.52 10.6 3.5 1.5 9.1 2.4 1.8 1 0 0 1 1 1 0 Snapin/Pallidin FNIP PF05725.7 GAM19458.1 - 2.7e-61 203.2 30.0 2.3e-12 46.6 0.0 8.2 7 3 3 10 10 10 8 FNIP Repeat FNIP PF05725.7 GAM19459.1 - 7.5e-12 45.0 10.3 9.2e-06 25.5 0.3 4.5 5 1 0 5 5 5 3 FNIP Repeat FNIP PF05725.7 GAM19460.1 - 6.3e-08 32.4 6.3 0.0026 17.6 0.0 4.0 4 0 0 4 4 4 2 FNIP Repeat LRR_9 PF14580.1 GAM19460.1 - 0.26 10.8 1.1 1.3 8.5 0.1 2.3 2 1 0 2 2 2 0 Leucine-rich repeat FNIP PF05725.7 GAM19461.1 - 4.8e-13 48.8 8.0 0.00021 21.1 0.0 5.1 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.7 GAM19463.1 - 0.035 14.0 0.2 0.26 11.2 0.0 2.4 1 1 1 2 2 2 0 FNIP Repeat FNIP PF05725.7 GAM19464.1 - 4.7e-11 42.4 6.0 0.0089 15.9 0.0 5.5 3 3 2 5 5 5 5 FNIP Repeat LRR_8 PF13855.1 GAM19464.1 - 3.6 7.4 10.9 1.9 8.3 0.0 5.0 4 2 1 5 5 5 0 Leucine rich repeat FNIP PF05725.7 GAM19465.1 - 8.1e-06 25.6 10.8 0.0079 16.1 0.0 5.4 4 2 1 5 5 5 2 FNIP Repeat FNIP PF05725.7 GAM19466.1 - 0.0067 16.3 0.6 0.0067 16.3 0.4 4.5 2 2 1 3 3 3 1 FNIP Repeat 2OG-FeII_Oxy_4 PF13661.1 GAM19466.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FNIP PF05725.7 GAM19467.1 - 1.4e-07 31.2 7.0 0.037 13.9 0.0 4.3 4 0 0 4 4 4 3 FNIP Repeat FNIP PF05725.7 GAM19468.1 - 1.7e-08 34.2 20.3 0.00099 19.0 0.0 7.7 6 2 0 7 7 7 4 FNIP Repeat FNIP PF05725.7 GAM19469.1 - 5.5e-06 26.2 8.0 0.018 14.9 0.4 5.9 3 2 1 4 4 4 3 FNIP Repeat FNIP PF05725.7 GAM19470.1 - 4.8e-11 42.4 13.3 0.019 14.8 0.0 7.1 5 1 1 6 6 6 5 FNIP Repeat F-box-like PF12937.2 GAM19470.1 - 7e-05 22.4 0.1 0.00022 20.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM19470.1 - 0.028 14.0 1.7 0.035 13.7 0.1 2.1 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 GAM19470.1 - 1.3 8.7 5.0 14 5.4 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 GAM19470.1 - 5.1 6.8 10.4 1.5 8.5 0.1 4.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 GAM19471.1 - 2.9e-06 27.1 4.2 0.00088 19.1 0.1 5.1 5 1 0 5 5 5 2 FNIP Repeat RICTOR_N PF14664.1 GAM19472.1 - 1e-85 287.6 2.8 1.8e-85 286.7 2.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 GAM19472.1 - 2.9e-65 219.4 2.9 1.9e-63 213.5 1.1 3.5 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 GAM19472.1 - 1e-34 118.9 0.1 9.9e-34 115.7 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 GAM19472.1 - 3.2e-29 100.6 0.0 9.1e-27 92.8 0.0 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 GAM19472.1 - 2.1e-08 34.3 0.0 0.002 18.3 0.0 4.4 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 GAM19472.1 - 0.001 18.9 0.9 1.6 9.0 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 GAM19472.1 - 0.0026 18.2 0.0 0.033 14.6 0.0 2.8 2 0 0 2 2 2 1 HEAT-like repeat Arm PF00514.18 GAM19472.1 - 0.043 13.6 0.1 2.3 8.1 0.0 4.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FNIP PF05725.7 GAM19473.1 - 1.2e-49 165.9 38.9 6.2e-12 45.2 0.0 11.2 10 3 2 12 12 12 9 FNIP Repeat Beta_helix PF13229.1 GAM19474.1 - 1.7e-08 34.3 22.8 1.7e-08 34.3 15.8 3.6 1 1 2 3 3 3 2 Right handed beta helix region ExbD PF02472.11 GAM19474.1 - 0.11 12.5 0.1 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Chlam_PMP PF02415.12 GAM19474.1 - 5.3 7.5 36.9 2.2 8.7 0.1 8.1 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4083 PF13314.1 GAM19474.1 - 7.6 6.4 8.2 1.5 8.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) FNIP PF05725.7 GAM19475.1 - 2.8e-55 183.9 8.4 8.1e-13 48.0 0.0 8.8 3 2 3 9 9 9 8 FNIP Repeat LRR_1 PF00560.28 GAM19475.1 - 1.7 8.9 6.9 37 4.9 0.2 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat Glutaredoxin PF00462.19 GAM19476.1 - 8.7e-21 73.6 0.1 1.2e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 GAM19476.1 - 0.00018 21.7 0.2 0.00028 21.0 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 GAM19476.1 - 0.0042 17.2 0.2 0.0061 16.7 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 GAM19476.1 - 0.0054 16.5 0.1 0.0089 15.8 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 GAM19476.1 - 0.01 15.3 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 GAM19476.1 - 0.016 15.2 0.3 2.9 7.8 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_3 PF13417.1 GAM19476.1 - 0.021 15.0 0.0 0.032 14.4 0.0 1.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM19476.1 - 0.028 14.4 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 GAM19476.1 - 0.035 13.6 0.2 0.74 9.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_7 PF13899.1 GAM19476.1 - 0.046 13.7 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.1 GAM19476.1 - 0.059 12.8 0.1 0.068 12.6 0.1 1.2 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF1012 PF06241.7 GAM19476.1 - 0.089 12.3 0.1 0.15 11.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1012) Zn_ribbon_2 PF12674.2 GAM19476.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain FNIP PF05725.7 GAM19477.1 - 6.8e-90 294.8 37.1 8.7e-12 44.8 0.0 10.3 5 2 10 15 15 15 13 FNIP Repeat GBP PF02263.14 GAM19478.1 - 4.3e-05 22.7 0.0 8.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 GAM19478.1 - 8.6e-05 22.4 0.1 0.00014 21.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase CENP-L PF13092.1 GAM19478.1 - 0.011 15.4 0.3 0.054 13.2 0.1 1.9 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 SHNi-TPR PF10516.4 GAM19478.1 - 0.014 14.6 0.4 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR FANCI_HD2 PF14680.1 GAM19478.1 - 0.02 13.9 0.2 0.044 12.8 0.0 1.6 2 0 0 2 2 2 0 FANCI helical domain 2 SWIRM PF04433.12 GAM19479.1 - 9.2e-30 102.6 0.1 2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAM19479.1 - 2.5e-08 33.8 0.1 4.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM19479.1 - 2.1e-05 24.5 0.2 5.6e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 GAM19479.1 - 0.055 13.0 0.3 0.055 13.0 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-DHHC PF01529.15 GAM19480.1 - 8.6e-41 139.2 6.4 8.6e-41 139.2 4.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase QueC PF06508.8 GAM19480.1 - 0.15 11.3 0.9 0.24 10.6 0.6 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PRELI PF04707.9 GAM19481.1 - 0.0048 16.4 0.3 0.0069 15.9 0.2 1.3 1 0 0 1 1 1 1 PRELI-like family ubiquitin PF00240.18 GAM19482.1 - 1.7e-14 52.9 0.1 2.4e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM19482.1 - 1.1e-07 31.4 0.2 1.4e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAM19482.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Aminotran_1_2 PF00155.16 GAM19483.1 - 1.3e-52 178.9 0.0 1.5e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM19483.1 - 7.6e-05 21.9 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase KH_3 PF13014.1 GAM19483.1 - 0.12 12.1 0.5 48 3.7 0.2 3.4 3 0 0 3 3 3 0 KH domain Aminotran_5 PF00266.14 GAM19483.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DSPc PF00782.15 GAM19484.1 - 1.1e-31 109.1 0.0 1.4e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM19484.1 - 0.00044 20.3 0.1 0.00051 20.1 0.1 1.3 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 GAM19484.1 - 0.0023 17.3 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 GAM19484.1 - 0.0033 16.3 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 GAM19484.1 - 0.056 13.6 0.2 0.29 11.3 0.1 1.9 1 1 1 2 2 2 0 Tyrosine phosphatase family UBX PF00789.15 GAM19486.1 - 5.7e-11 42.3 0.1 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.18 GAM19486.1 - 0.00032 20.0 0.3 0.0036 16.6 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin family Ubiquitin_2 PF14560.1 GAM19486.1 - 0.0091 16.2 0.2 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-like domain Thioredoxin_7 PF13899.1 GAM19486.1 - 0.025 14.5 0.1 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin-like BNIP3 PF06553.7 GAM19486.1 - 0.2 10.9 1.5 0.48 9.7 1.1 1.7 1 0 0 1 1 1 0 BNIP3 RNase_Zc3h12a PF11977.3 GAM19487.1 - 4.4e-31 107.8 0.0 8.1e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Cna_B PF05738.8 GAM19489.1 - 5e-06 26.1 0.7 0.011 15.5 0.1 3.0 3 0 0 3 3 3 2 Cna protein B-type domain DUF1842 PF08896.5 GAM19489.1 - 0.038 13.7 0.0 1 9.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1842) Ribosomal_S11 PF00411.14 GAM19490.1 - 2.2e-38 130.7 0.5 2.9e-38 130.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Pet20 PF08692.5 GAM19491.1 - 0.024 14.5 0.0 0.024 14.5 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial protein Pet20 HARE-HTH PF05066.8 GAM19491.1 - 0.1 12.9 0.4 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Ribosomal_S17 PF00366.15 GAM19493.1 - 3.6e-15 55.7 0.8 5.5e-15 55.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 zf-C4H2 PF10146.4 GAM19494.1 - 1.2e-15 58.1 3.1 1.6e-15 57.7 2.1 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein RasGAP_C PF03836.10 GAM19494.1 - 0.0012 18.5 4.5 0.0012 18.5 3.1 1.9 1 1 1 2 2 2 1 RasGAP C-terminus V_ATPase_I PF01496.14 GAM19494.1 - 0.056 11.3 3.9 0.065 11.0 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PLRV_ORF5 PF01690.12 GAM19494.1 - 0.22 10.6 2.8 0.27 10.3 2.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FNIP PF05725.7 GAM19495.1 - 4e-37 125.9 19.4 1.2e-13 50.7 0.8 5.3 3 2 1 5 5 5 5 FNIP Repeat Iron_traffic PF04362.9 GAM19495.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Ank_2 PF12796.2 GAM19496.1 - 1.8e-14 53.8 11.8 0.0035 17.6 0.0 8.5 7 1 0 7 7 7 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM19496.1 - 2.9e-06 26.8 3.6 0.039 13.7 0.0 7.3 8 0 0 8 8 8 1 Ankyrin repeat Ank_3 PF13606.1 GAM19496.1 - 5.8e-06 26.0 14.1 0.08 13.2 0.0 10.3 13 0 0 13 13 13 1 Ankyrin repeat Ank_4 PF13637.1 GAM19496.1 - 3.3e-05 24.2 9.0 0.88 10.1 0.0 7.8 7 2 0 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19496.1 - 0.00067 19.8 5.7 5.2 7.4 0.0 7.2 7 1 1 8 8 8 1 Ankyrin repeats (many copies) APCDDC PF14921.1 GAM19496.1 - 0.0018 17.6 0.0 0.0057 16.0 0.0 1.8 1 0 0 1 1 1 1 Adenomatosis polyposis coli down-regulated 1 adh_short PF00106.20 GAM19497.1 - 3.6e-31 108.3 0.1 5.6e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM19497.1 - 7.7e-16 58.5 0.0 1.1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM19497.1 - 7.1e-14 51.8 0.0 1.3e-13 50.9 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 GAM19497.1 - 1.5e-06 27.8 0.1 3.7e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM19497.1 - 2.1e-06 27.8 0.1 4e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM19497.1 - 0.0078 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FliH PF02108.11 GAM19497.1 - 0.046 13.6 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Flagellar assembly protein FliH NmrA PF05368.8 GAM19497.1 - 0.1 11.8 0.3 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Mob1_phocein PF03637.12 GAM19498.1 - 5.6e-78 260.6 0.1 6.5e-78 260.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family PAS_3 PF08447.6 GAM19499.1 - 6.1e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 GAM19499.1 - 2e-05 24.8 0.0 6.4e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain Zn_clus PF00172.13 GAM19499.1 - 0.00087 19.1 5.9 0.0014 18.4 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1624 PF07786.7 GAM19500.1 - 1.6e-07 30.9 7.6 1.6e-07 30.9 5.3 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1624) Tim17 PF02466.14 GAM19501.1 - 2.5e-17 63.1 1.4 4.5e-17 62.2 1.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_9 PF00759.14 GAM19502.1 - 1.2e-100 337.4 16.8 1.2e-100 337.4 11.7 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 DUF2708 PF10917.3 GAM19502.1 - 0.18 11.5 2.1 0.6 9.9 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2708) Ibs_toxin PF13956.1 GAM19502.1 - 0.85 9.4 5.5 1.9 8.3 3.8 1.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Peptidase_M16 PF00675.15 GAM19503.1 - 2.4e-35 121.4 0.5 5.4e-35 120.3 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAM19503.1 - 9.2e-22 77.5 1.2 7.4e-15 55.0 0.0 4.0 5 1 0 5 5 5 2 Peptidase M16 inactive domain CAP PF00188.21 GAM19504.1 - 4.9e-09 36.7 0.0 9.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RhoGAP PF00620.22 GAM19505.1 - 1e-29 103.1 1.0 2.9e-29 101.6 0.2 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 GAM19505.1 - 0.00076 19.6 2.3 0.02 15.1 1.0 3.1 2 1 0 2 2 2 1 PH domain Pkinase PF00069.20 GAM19506.1 - 5.2e-55 186.3 0.0 7.5e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19506.1 - 2.4e-43 148.0 0.0 3.4e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19506.1 - 4.6e-06 25.8 0.0 7.3e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2363 PF10155.4 GAM19506.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) Macoilin PF09726.4 GAM19506.1 - 0.69 8.1 8.6 0.9 7.7 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 GAM19506.1 - 1.5 8.1 18.1 2.3 7.5 12.6 1.2 1 0 0 1 1 1 0 Vta1 like Upf2 PF04050.9 GAM19506.1 - 1.8 8.3 11.5 4.5 7.0 8.0 1.6 1 1 0 1 1 1 0 Up-frameshift suppressor 2 Pox_RNA_Pol_19 PF05320.7 GAM19506.1 - 4.4 7.0 7.3 8.3 6.1 5.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SDA1 PF05285.7 GAM19506.1 - 4.5 6.4 8.8 6.9 5.8 6.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 GAM19506.1 - 6 4.6 10.7 11 3.8 7.4 1.3 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 GAM19507.1 - 3.5e-85 277.1 14.2 4.1e-11 42.3 0.3 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 GAM19507.1 - 2.5e-16 59.4 1.6 4.1e-16 58.7 1.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 GAM19507.1 - 3.2e-10 40.0 0.6 0.0094 15.6 0.0 4.1 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM19507.1 - 5.5e-10 38.0 0.6 0.12 10.5 0.0 4.8 4 2 2 6 6 6 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 GAM19507.1 - 3.5e-05 23.0 0.2 0.035 13.2 0.0 4.1 2 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 GAM19507.1 - 0.014 14.1 0.0 0.64 8.7 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region BBS2_Mid PF14783.1 GAM19507.1 - 0.018 14.7 0.0 11 5.8 0.0 3.6 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DPPIV_N PF00930.16 GAM19507.1 - 0.03 12.9 0.2 1 7.8 0.0 2.8 3 0 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 GAM19507.1 - 0.07 12.8 3.1 42 3.9 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RhoGEF PF00621.15 GAM19509.1 - 1.8e-49 168.0 1.8 1.8e-49 168.0 1.3 2.5 2 0 0 2 2 2 1 RhoGEF domain PX PF00787.19 GAM19509.1 - 1.2e-18 66.9 0.8 3.5e-18 65.4 0.5 1.9 1 0 0 1 1 1 1 PX domain CH PF00307.26 GAM19509.1 - 7.1e-09 35.6 0.1 2.1e-07 30.9 0.0 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 GAM19509.1 - 0.00098 18.5 1.4 0.0025 17.2 1.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Trypan_PARP PF05887.6 GAM19509.1 - 6.7 6.5 11.5 16 5.3 8.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATG_C PF09333.6 GAM19510.1 - 7.9e-33 112.5 0.3 2.1e-32 111.1 0.2 1.8 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 GAM19510.1 - 8.7e-11 41.4 0.0 2.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Cna_B PF05738.8 GAM19511.1 - 2.1e-108 354.1 139.7 3e-06 26.8 1.3 31.8 30 0 0 30 30 30 29 Cna protein B-type domain DUF2012 PF09430.5 GAM19511.1 - 2.5e-27 95.1 33.9 0.69 9.7 0.0 24.5 26 0 0 26 26 26 3 Protein of unknown function (DUF2012) DUF1842 PF08896.5 GAM19511.1 - 2e-14 53.2 12.6 2.9 7.6 0.0 12.5 13 0 0 13 13 13 4 Domain of unknown function (DUF1842) Cro PF09048.5 GAM19511.1 - 9.3e-08 31.5 5.0 13 5.5 0.0 10.4 11 0 0 11 11 11 1 Cro YqhG PF11079.3 GAM19511.1 - 5.6e-05 22.0 0.0 59 2.3 0.0 9.7 13 0 0 13 13 13 0 Bacterial protein YqhG of unknown function Transposase_23 PF03017.9 GAM19511.1 - 0.00057 19.3 0.1 73 2.9 0.0 7.5 8 0 0 8 8 8 0 TNP1/EN/SPM transposase Acetyltransf_9 PF13527.1 GAM19511.1 - 0.031 14.1 0.0 1.3e+02 2.4 0.0 5.3 5 0 0 5 5 5 0 Acetyltransferase (GNAT) domain Avidin PF01382.12 GAM19511.1 - 0.11 12.8 29.7 13 6.0 0.1 11.1 13 0 0 13 13 13 0 Avidin family PduL PF06130.7 GAM19511.1 - 3.7 7.4 4.4 4.9e+02 0.6 0.0 5.6 7 0 0 7 7 7 0 Propanediol utilisation protein PduL Cro PF09048.5 GAM19512.1 - 1.7e-05 24.3 0.2 1.2 8.8 0.0 3.8 3 0 0 3 3 3 3 Cro UNC-50 PF05216.8 GAM19513.1 - 2.8e-86 288.5 32.1 3.2e-86 288.3 22.3 1.0 1 0 0 1 1 1 1 UNC-50 family THUMP PF02926.12 GAM19515.1 - 1.9e-08 34.3 5.4 6.9e-08 32.4 1.9 2.1 2 0 0 2 2 2 1 THUMP domain Herpes_UL6 PF01763.11 GAM19515.1 - 0.0035 15.5 0.8 0.0055 14.9 0.5 1.3 1 0 0 1 1 1 1 Herpesvirus UL6 like DUF3949 PF13133.1 GAM19515.1 - 0.011 15.9 0.1 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3949) BCS1_N PF08740.6 GAM19516.1 - 2.5e-50 170.7 0.5 4.3e-50 169.9 0.4 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 GAM19516.1 - 1.6e-15 57.4 0.0 5.4e-14 52.5 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM19516.1 - 0.00045 21.0 0.0 0.0014 19.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM19516.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 GAM19516.1 - 0.0017 17.7 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM19516.1 - 0.0024 17.9 0.1 0.0067 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 GAM19516.1 - 0.0042 16.9 0.0 0.019 14.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 GAM19516.1 - 0.012 15.9 0.1 0.043 14.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 GAM19516.1 - 0.013 15.6 0.0 0.085 13.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 GAM19516.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM19516.1 - 0.023 14.8 0.0 0.084 13.0 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 GAM19516.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_PrkA PF08298.6 GAM19516.1 - 0.039 12.6 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_19 PF13245.1 GAM19516.1 - 0.041 13.6 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 GAM19516.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAM19516.1 - 0.091 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Miro PF08477.8 GAM19516.1 - 0.1 13.0 0.0 0.42 11.1 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 GAM19516.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.7 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.8 GAM19516.1 - 0.15 10.7 0.0 0.56 8.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus Mucin PF01456.12 GAM19517.1 - 4.5 7.0 24.1 0.3 10.8 13.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 GAM19517.1 - 5.2 4.7 10.2 5.5 4.6 7.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein dDENN PF03455.14 GAM19518.1 - 2.6e-05 24.1 0.2 5e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 dDENN domain UPF1_Zn_bind PF09416.5 GAM19518.1 - 0.0074 15.8 0.1 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) LIM PF00412.17 GAM19518.1 - 0.01 15.8 3.6 0.032 14.3 2.5 1.9 1 0 0 1 1 1 0 LIM domain PP2 PF14299.1 GAM19518.1 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Phloem protein 2 RNHCP PF12647.2 GAM19518.1 - 0.13 12.1 1.9 0.65 9.8 0.1 2.3 2 0 0 2 2 2 0 RNHCP domain Cys_rich_KTR PF14205.1 GAM19518.1 - 0.55 9.7 3.4 1.7 8.1 0.7 2.4 2 0 0 2 2 2 0 Cysteine-rich KTR GST_N_2 PF13409.1 GAM19519.1 - 3.3e-17 62.2 0.0 9.8e-17 60.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM19519.1 - 1.4e-10 40.8 0.0 2.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM19519.1 - 6.1e-07 29.3 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM19519.1 - 0.0092 16.4 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM19519.1 - 0.01 16.0 0.2 0.24 11.6 0.1 2.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Phi_1 PF04674.7 GAM19519.1 - 0.12 11.5 0.0 0.85 8.7 0.0 2.0 2 0 0 2 2 2 0 Phosphate-induced protein 1 conserved region Pkinase_Tyr PF07714.12 GAM19520.1 - 1.9e-65 220.4 0.0 2.8e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM19520.1 - 1.1e-60 205.0 0.0 1.6e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAM19520.1 - 0.00014 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 GAM19521.1 - 3.3e-63 213.1 0.0 4.2e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM19521.1 - 2.6e-58 197.2 0.0 3.5e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAM19521.1 - 0.00032 20.5 0.0 0.00061 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family gpUL132 PF11359.3 GAM19521.1 - 0.083 12.2 6.9 0.15 11.3 4.8 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 Seadorna_VP7 PF07387.6 GAM19521.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_38 PF01074.17 GAM19522.1 - 1.2e-85 287.0 1.7 1.9e-85 286.4 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM19522.1 - 3.7e-66 223.7 2.6 4.7e-66 223.4 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM19522.1 - 1.8e-19 69.6 0.1 4.4e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 GAM19522.1 - 0.0045 15.9 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Filamin PF00630.14 GAM19523.1 - 3.4e-125 409.5 10.9 5.1e-23 81.5 0.1 6.2 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.26 GAM19523.1 - 8.5e-34 115.8 0.3 9.1e-17 61.0 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Big_1 PF02369.11 GAM19523.1 - 3.2e-14 52.6 6.9 0.075 12.9 0.0 6.3 6 0 0 6 6 6 5 Bacterial Ig-like domain (group 1) Y_Y_Y PF07495.8 GAM19523.1 - 2e-09 37.0 2.3 0.25 11.1 0.0 5.8 5 0 0 5 5 5 4 Y_Y_Y domain CAMSAP_CH PF11971.3 GAM19523.1 - 5.9e-07 29.0 0.0 0.0018 17.9 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain YtkA PF13115.1 GAM19523.1 - 2.3e-06 27.8 8.5 0.24 11.7 0.0 5.9 6 0 0 6 6 6 2 YtkA-like Big_3_4 PF13754.1 GAM19523.1 - 0.012 15.9 1.2 0.012 15.9 0.8 7.5 6 3 3 9 9 9 0 Bacterial Ig-like domain (group 3) Neurexophilin PF06312.7 GAM19523.1 - 0.19 10.9 5.1 54 2.9 0.0 4.8 5 1 1 6 6 6 0 Neurexophilin FlgD_ig PF13860.1 GAM19523.1 - 6.7 6.5 13.9 26 4.6 0.1 6.2 6 2 1 7 7 7 0 FlgD Ig-like domain zf-RING_2 PF13639.1 GAM19524.1 - 6e-07 29.1 7.9 6e-07 29.1 5.5 1.9 2 0 0 2 2 2 1 Ring finger domain FH2 PF02181.18 GAM19525.1 - 4.6e-91 305.4 3.7 1.4e-90 303.8 0.2 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAM19525.1 - 3.2e-33 114.6 0.3 1e-32 113.0 0.2 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAM19525.1 - 3.7e-33 114.6 0.0 3.7e-33 114.6 0.0 2.6 2 0 0 2 2 2 1 Diaphanous FH3 Domain Med9 PF07544.8 GAM19525.1 - 8.9e-05 22.1 5.6 0.37 10.5 0.2 3.8 3 0 0 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.6 GAM19525.1 - 0.0008 19.2 9.2 0.13 12.2 0.2 4.5 4 0 0 4 4 4 2 Flagella accessory protein C (FlaC) SPATA24 PF15175.1 GAM19525.1 - 0.0027 17.3 1.2 0.013 15.2 0.8 2.1 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Baculo_PEP_C PF04513.7 GAM19525.1 - 0.0063 16.3 7.6 2.8 7.7 3.2 3.7 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_GP20 PF06810.6 GAM19525.1 - 0.0092 15.4 13.0 0.1 12.0 2.7 3.8 3 0 0 3 3 3 1 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 GAM19525.1 - 0.012 15.4 15.8 0.053 13.3 0.1 3.8 4 0 0 4 4 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 GAM19525.1 - 0.014 15.3 16.4 0.057 13.4 2.4 3.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 GAM19525.1 - 0.016 14.8 11.5 1 8.9 1.4 3.5 3 0 0 3 3 3 0 Mnd1 family RNase_PH PF01138.16 GAM19525.1 - 0.031 14.6 0.1 0.082 13.2 0.1 1.8 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 ADIP PF11559.3 GAM19525.1 - 0.049 13.5 16.5 0.08 12.8 4.6 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 GAM19525.1 - 0.069 12.0 10.7 0.36 9.7 5.0 2.7 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 GAM19525.1 - 0.085 12.8 9.7 3 7.8 0.3 4.2 3 0 0 3 3 3 0 bZIP transcription factor SlyX PF04102.7 GAM19525.1 - 0.11 12.8 13.8 7.7 6.9 4.2 4.9 3 1 1 4 4 4 0 SlyX TMF_TATA_bd PF12325.3 GAM19525.1 - 0.26 11.0 13.4 2.5 7.8 2.8 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.10 GAM19525.1 - 0.26 10.4 7.9 0.36 9.9 0.4 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.3 GAM19525.1 - 1.5 8.6 23.9 0.39 10.5 6.1 4.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 GAM19525.1 - 2 6.1 7.4 0.47 8.2 1.5 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3597 PF12200.3 GAM19525.1 - 2.1 8.7 15.1 0.41 11.0 3.1 3.8 4 0 0 4 4 3 0 Domain of unknown function (DUF3597) Reo_sigmaC PF04582.7 GAM19525.1 - 2.4 7.2 11.2 1.6 7.8 1.1 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 GAM19525.1 - 2.9 6.4 14.9 4 6.0 5.2 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF3138 PF11336.3 GAM19525.1 - 3.4 5.7 11.1 0.39 8.8 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Prefoldin PF02996.12 GAM19525.1 - 3.7 7.2 12.9 2.7 7.6 1.6 4.1 3 0 0 3 3 3 0 Prefoldin subunit DUF3573 PF12097.3 GAM19525.1 - 4 5.9 7.3 0.94 8.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) DUF972 PF06156.8 GAM19525.1 - 5.2 7.4 13.7 1 9.7 0.6 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF972) Mto2_bdg PF12808.2 GAM19525.1 - 5.3 7.2 10.2 0.096 12.8 0.3 3.0 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CDC37_N PF03234.9 GAM19525.1 - 5.4 7.2 14.5 0.046 14.0 2.5 2.9 3 0 0 3 3 2 0 Cdc37 N terminal kinase binding AAA_13 PF13166.1 GAM19525.1 - 5.7 5.2 10.7 1.5 7.2 1.9 2.3 2 0 0 2 2 2 0 AAA domain Filament PF00038.16 GAM19525.1 - 6.5 6.1 16.8 1.3 8.3 3.3 3.0 3 0 0 3 3 3 0 Intermediate filament protein DUF904 PF06005.7 GAM19525.1 - 7 7.0 16.9 3.7 7.9 3.4 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF904) DUF4201 PF13870.1 GAM19525.1 - 8.5 5.7 15.7 0.32 10.4 1.4 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4201) Totivirus_coat PF05518.6 GAM19525.1 - 9.6 3.8 17.6 16 3.1 12.2 1.4 1 0 0 1 1 1 0 Totivirus coat protein HATPase_c PF02518.21 GAM19526.1 - 3e-48 162.1 0.1 1e-22 79.9 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM19526.1 - 5.7e-45 151.9 1.8 1.5e-24 86.1 0.0 3.2 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 GAM19526.1 - 7.2e-31 105.9 0.5 2.5e-14 53.0 0.0 3.3 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 GAM19526.1 - 2e-07 31.2 0.0 1.6e-06 28.4 0.0 2.6 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 GAM19526.1 - 1.1e-06 28.6 0.0 5.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold NOD PF06816.8 GAM19526.1 - 0.046 12.8 0.3 5.2 6.2 0.0 2.6 2 0 0 2 2 2 0 NOTCH protein DUF2328 PF10090.4 GAM19526.1 - 0.058 12.5 0.0 2 7.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2328) PWI PF01480.12 GAM19527.1 - 3e-23 81.6 0.0 4.7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 PWI domain Phage_term_smal PF05944.7 GAM19527.1 - 0.047 13.3 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Phage small terminase subunit Uricase PF01014.13 GAM19528.1 - 3.1e-65 218.4 5.7 1.7e-35 122.1 1.9 2.0 2 0 0 2 2 2 2 Uricase NTNH_C PF08470.5 GAM19528.1 - 0.057 13.0 0.8 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Nontoxic nonhaemagglutinin C-terminal DNA_pol_B_2 PF03175.8 GAM19529.1 - 0.024 13.3 1.9 0.12 11.0 1.3 2.0 1 1 0 1 1 1 0 DNA polymerase type B, organellar and viral FNIP PF05725.7 GAM19530.1 - 1.8e-25 88.6 0.6 5.1e-11 42.3 0.1 3.9 4 0 0 4 4 4 3 FNIP Repeat F-box-like PF12937.2 GAM19530.1 - 0.008 15.8 0.5 0.019 14.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like DNase_II PF03265.10 GAM19531.1 - 7.9e-11 41.5 0.4 2.1e-08 33.5 0.0 2.1 1 1 0 2 2 2 2 Deoxyribonuclease II LRR_6 PF13516.1 GAM19532.1 - 3.4e-10 38.9 43.4 0.16 12.1 0.0 16.5 18 0 0 18 18 18 3 Leucine Rich repeat IstB_IS21 PF01695.12 GAM19532.1 - 0.0004 19.8 0.0 0.0013 18.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 GAM19532.1 - 0.0018 18.3 0.2 0.21 11.7 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 GAM19532.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LRR_7 PF13504.1 GAM19532.1 - 0.0063 16.5 18.0 18 6.1 0.0 11.2 11 0 0 11 11 11 1 Leucine rich repeat AAA_33 PF13671.1 GAM19532.1 - 0.07 13.0 0.0 0.07 13.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAM19532.1 - 0.16 11.9 0.0 0.16 11.9 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.1 GAM19532.1 - 0.36 10.7 3.9 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 GAM19534.1 - 3.1e-38 131.4 0.9 5.4e-38 130.6 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19534.1 - 6.4e-20 71.3 0.6 1e-19 70.6 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19534.1 - 0.099 11.5 0.0 13 4.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Ribosomal_L32e PF01655.13 GAM19535.1 - 5e-43 145.6 0.4 6.1e-43 145.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 CybS PF05328.7 GAM19536.1 - 7.9e-11 41.7 2.2 9.4e-11 41.4 1.4 1.3 1 1 0 1 1 1 1 CybS PseudoU_synth_2 PF00849.17 GAM19537.1 - 3.9e-30 104.8 9.6 9.1e-16 58.1 0.0 3.5 3 1 0 3 3 3 2 RNA pseudouridylate synthase NCA2 PF08637.5 GAM19538.1 - 1.3e-57 194.8 3.3 1.3e-57 194.8 2.3 2.1 3 0 0 3 3 3 1 ATP synthase regulation protein NCA2 DASH_Dad3 PF08656.5 GAM19538.1 - 0.042 13.5 0.3 0.042 13.5 0.2 3.9 5 0 0 5 5 5 0 DASH complex subunit Dad3 RhoGAP PF00620.22 GAM19539.1 - 2.6e-31 108.2 1.3 3.6e-31 107.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain zf-MYND PF01753.13 GAM19539.1 - 4.9e-11 42.3 10.6 8.3e-11 41.5 7.3 1.4 1 0 0 1 1 1 1 MYND finger ADH_zinc_N PF00107.21 GAM19540.1 - 6.7e-28 96.8 0.4 1.2e-27 96.0 0.2 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM19540.1 - 1.7e-15 58.0 0.1 6e-15 56.2 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM19540.1 - 3.9e-11 42.6 0.0 7.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GMC_oxred_N PF00732.14 GAM19541.1 - 4.1e-46 157.4 0.0 7.6e-46 156.6 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM19541.1 - 5.5e-29 101.3 0.2 9.1e-29 100.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 GAM19541.1 - 0.00042 20.2 0.6 0.00098 19.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM19541.1 - 0.003 16.5 0.6 0.0065 15.4 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM19541.1 - 0.02 13.3 0.1 0.037 12.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 GAM19541.1 - 0.028 13.2 3.7 0.024 13.4 1.5 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 GAM19541.1 - 0.034 14.0 0.7 0.078 12.8 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 GAM19541.1 - 0.076 12.4 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 GAM19541.1 - 0.086 11.9 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 Thi4 family JAB PF01398.16 GAM19542.1 - 3.9e-11 42.6 0.0 7.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Streptin-Immun PF11083.3 GAM19542.1 - 0.046 13.7 0.6 0.21 11.6 0.2 2.3 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Phage_CRI PF05144.9 GAM19542.1 - 0.048 12.7 0.3 0.074 12.1 0.2 1.2 1 0 0 1 1 1 0 Phage replication protein CRI DUF2012 PF09430.5 GAM19543.1 - 1.4e-18 66.9 0.5 3.8e-18 65.5 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) Y_Y_Y PF07495.8 GAM19543.1 - 0.027 14.2 0.1 0.076 12.7 0.0 1.7 2 0 0 2 2 2 0 Y_Y_Y domain CarboxypepD_reg PF13620.1 GAM19543.1 - 0.038 14.0 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Peptidase_M66 PF10462.4 GAM19544.1 - 1.4e-25 89.7 0.0 1.8e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM19544.1 - 0.042 14.3 1.1 0.042 14.3 0.7 1.7 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 GAM19544.1 - 0.1 11.0 0.3 0.16 10.3 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.19 GAM19544.1 - 0.14 11.8 1.0 0.19 11.4 0.7 1.4 1 1 0 1 1 1 0 Matrixin DEC-1_N PF04625.8 GAM19545.1 - 5.4 5.5 9.6 8 5.0 6.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region P2X_receptor PF00864.14 GAM19547.1 - 3.4e-19 68.7 8.7 2.6e-10 39.5 1.6 2.9 2 1 1 3 3 3 2 ATP P2X receptor ATG_C PF09333.6 GAM19548.1 - 7.7e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 ATG C terminal domain DUF1162 PF06650.7 GAM19549.1 - 3.5e-38 131.3 0.4 3.5e-38 131.3 0.3 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM19549.1 - 3.1e-36 123.4 1.3 3.1e-36 123.4 0.9 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF3040 PF11239.3 GAM19549.1 - 0.4 10.7 0.4 1 9.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Pkinase PF00069.20 GAM19550.1 - 3.5e-66 223.0 0.0 4.4e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19550.1 - 1.1e-48 165.5 0.0 1.6e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.6 GAM19550.1 - 2.8e-06 26.6 0.0 7.2e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.1 GAM19550.1 - 9.5e-06 24.7 0.0 0.00013 21.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF607 PF04678.8 GAM19551.1 - 5.2e-44 150.3 0.0 8.3e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Peptidase_M14 PF00246.19 GAM19552.1 - 3.5e-71 240.0 0.4 4.5e-71 239.7 0.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 GAM19552.1 - 7.9e-07 29.0 0.1 1.6e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2817 PF10994.3 GAM19552.1 - 0.00069 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) DUF4480 PF13715.1 GAM19552.1 - 0.003 17.5 0.2 0.0065 16.4 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) PEGA PF08308.6 GAM19552.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 PEGA domain AstE_AspA PF04952.9 GAM19552.1 - 0.0071 15.2 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family EF-hand_7 PF13499.1 GAM19553.1 - 4.6e-23 81.1 9.2 5.9e-09 35.9 1.5 5.0 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.27 GAM19553.1 - 3.6e-20 69.6 16.4 0.00015 20.8 0.3 5.9 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 GAM19553.1 - 5.9e-16 56.8 12.8 0.005 16.6 0.0 6.1 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 GAM19553.1 - 8.2e-16 57.3 10.3 2.5e-06 27.0 0.1 4.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM19553.1 - 3.4e-14 51.4 12.6 0.00066 18.9 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 GAM19553.1 - 3.3e-06 26.7 3.6 0.38 10.5 0.0 3.6 2 1 1 3 3 3 3 Cytoskeletal-regulatory complex EF hand VCBS PF13517.1 GAM19553.1 - 0.00054 20.2 0.2 2.3 8.6 0.0 3.8 4 0 0 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SPARC_Ca_bdg PF10591.4 GAM19553.1 - 0.0015 18.5 0.0 0.038 14.0 0.0 3.1 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 GAM19554.1 - 3.2e-38 131.3 0.1 4.8e-38 130.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19554.1 - 1.5e-21 76.6 0.0 1.9e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM19554.1 - 0.0032 17.2 0.0 0.34 10.6 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Prefoldin_2 PF01920.15 GAM19555.1 - 5.5e-14 51.8 7.9 7.2e-14 51.4 5.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4618 PF15397.1 GAM19555.1 - 0.00021 20.6 7.0 0.00043 19.7 4.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.6 GAM19555.1 - 0.011 14.3 1.0 0.011 14.3 0.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4132 PF13569.1 GAM19555.1 - 0.081 12.4 0.4 0.14 11.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) XhlA PF10779.4 GAM19555.1 - 0.12 12.2 4.7 2.6 8.0 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Uds1 PF15456.1 GAM19555.1 - 0.14 12.1 2.7 0.44 10.5 1.9 1.8 1 1 0 1 1 1 0 Up-regulated During Septation WXG100 PF06013.7 GAM19555.1 - 0.19 11.7 1.2 2 8.4 0.1 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.17 GAM19555.1 - 0.23 11.5 8.6 1.3 9.0 1.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3847 PF12958.2 GAM19555.1 - 0.24 11.1 7.0 1.5 8.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) CENP-F_leu_zip PF10473.4 GAM19555.1 - 0.28 11.0 8.3 0.35 10.7 0.8 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 GAM19555.1 - 0.39 10.5 8.4 0.43 10.4 2.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Lebercilin PF15619.1 GAM19555.1 - 1.1 8.6 8.6 1.6 8.1 0.5 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF342 PF03961.8 GAM19555.1 - 1.4 7.2 7.7 4.2 5.6 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FlxA PF14282.1 GAM19555.1 - 1.9 8.4 10.7 2.3 8.2 1.5 2.2 1 1 0 2 2 2 0 FlxA-like protein Spc24 PF08286.6 GAM19555.1 - 1.9 8.2 7.4 3.3 7.4 1.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 GAM19555.1 - 3.1 7.7 6.7 15 5.5 0.3 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) IBR PF01485.16 GAM19556.1 - 4.9e-18 64.7 40.0 1.4e-11 44.0 4.5 4.3 3 1 1 4 4 4 2 IBR domain CUE PF02845.11 GAM19556.1 - 4e-08 32.5 0.2 8.8e-08 31.4 0.2 1.6 1 0 0 1 1 1 1 CUE domain zf-RING_2 PF13639.1 GAM19556.1 - 2.9e-05 23.8 8.1 2.9e-05 23.8 5.6 4.3 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.20 GAM19556.1 - 4.6e-05 22.9 8.2 4.6e-05 22.9 5.7 4.5 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM19556.1 - 0.0017 18.3 8.8 0.0017 18.3 6.1 4.5 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM19556.1 - 0.017 14.8 7.2 0.017 14.8 5.0 4.1 3 1 1 4 4 4 0 zinc-RING finger domain Mob_synth_C PF06463.8 GAM19556.1 - 1 9.0 7.1 0.28 10.8 0.7 2.7 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C Aldedh PF00171.17 GAM19558.1 - 1.2e-100 337.1 0.0 1.4e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyt-b5 PF00173.23 GAM19559.1 - 1.8e-19 69.2 0.0 4.2e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 GAM19559.1 - 1.5e-17 64.0 0.1 9.3e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM19559.1 - 3.1e-09 36.8 0.0 6.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAM19559.1 - 0.00056 19.8 6.4 0.00076 19.4 0.0 3.2 3 1 1 4 4 4 1 Ferric reductase NAD binding domain Ashwin PF15323.1 GAM19559.1 - 0.67 9.9 8.9 0.11 12.4 3.3 1.7 2 0 0 2 2 2 0 Developmental protein PEX11 PF05648.9 GAM19560.1 - 3.9e-49 166.9 8.7 1.2e-48 165.3 6.0 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pox_I6 PF04595.8 GAM19560.1 - 0.068 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family DUF1324 PF07038.6 GAM19561.1 - 0.046 13.7 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) DUF3937 PF13073.1 GAM19561.1 - 1.4 8.8 4.8 0.57 10.1 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3937) Beta-lactamase2 PF13354.1 GAM19562.1 - 0.00046 19.6 0.0 0.0023 17.4 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase enzyme family MFS_1 PF07690.11 GAM19563.1 - 1.8e-56 191.4 54.1 1e-55 188.9 37.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 GAM19563.1 - 7e-22 77.3 29.1 1e-21 76.7 20.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 GAM19563.1 - 2e-14 53.0 16.2 2e-14 53.0 11.2 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 GAM19563.1 - 8.7e-05 20.8 17.4 0.0062 14.7 2.8 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector DUF2407_C PF13373.1 GAM19563.1 - 0.12 12.2 1.6 0.3 10.9 0.1 2.6 2 0 0 2 2 2 0 DUF2407 C-terminal domain Enolase_C PF00113.17 GAM19564.1 - 3.6e-148 492.3 0.0 5.9e-148 491.6 0.0 1.3 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 GAM19564.1 - 1.6e-60 202.7 0.6 2.6e-60 202.1 0.4 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 GAM19564.1 - 0.00016 20.7 0.6 0.00035 19.5 0.0 1.8 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 GAM19564.1 - 0.006 17.0 0.0 0.02 15.4 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 GAM19564.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like zf-C3HC4 PF00097.20 GAM19565.1 - 2e-08 33.7 13.0 2e-08 33.7 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAM19565.1 - 1.7e-07 30.8 4.2 3.9e-07 29.7 2.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 GAM19565.1 - 1.8e-06 27.5 10.8 1.8e-06 27.5 7.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM19565.1 - 1.9e-06 27.5 10.8 1.9e-06 27.5 7.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM19565.1 - 3.7e-06 26.8 13.2 3.7e-06 26.8 9.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 GAM19565.1 - 6.2e-06 25.5 0.0 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.1 GAM19565.1 - 2.1e-05 24.1 8.2 2.1e-05 24.1 5.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM19565.1 - 0.00041 20.1 12.6 0.00041 20.1 8.8 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 GAM19565.1 - 0.0032 17.5 3.7 0.0082 16.2 2.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM19565.1 - 0.005 16.6 4.1 0.011 15.5 2.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAM19565.1 - 0.011 15.3 9.5 0.039 13.6 6.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 GAM19565.1 - 0.018 14.5 9.5 0.018 14.5 6.6 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger YdjO PF14169.1 GAM19565.1 - 0.025 14.0 1.6 0.025 14.0 1.1 2.6 3 1 1 4 4 3 0 Cold-inducible protein YdjO U-box PF04564.10 GAM19565.1 - 0.051 13.5 0.6 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 U-box domain DUF329 PF03884.9 GAM19565.1 - 0.094 12.2 2.6 6.9 6.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zf-RING_4 PF14570.1 GAM19565.1 - 0.69 9.5 13.8 0.15 11.6 5.8 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rubredoxin PF00301.15 GAM19565.1 - 1.9 8.4 4.2 5 7.0 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin zf-H2C2_2 PF13465.1 GAM19565.1 - 5 7.6 14.0 0.78 10.1 2.9 3.6 3 0 0 3 3 3 0 Zinc-finger double domain AAA PF00004.24 GAM19566.1 - 4.3e-58 195.2 0.0 8.8e-43 145.6 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 GAM19566.1 - 8.6e-25 86.5 2.1 2.2e-24 85.3 1.4 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 GAM19566.1 - 1.4e-10 41.5 0.2 0.00038 20.4 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 GAM19566.1 - 6.4e-10 39.8 0.4 0.00032 21.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 GAM19566.1 - 9e-09 35.0 0.4 0.0017 17.7 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.9 GAM19566.1 - 3.7e-08 33.1 0.1 0.0065 16.2 0.0 4.0 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM19566.1 - 1e-07 32.1 0.1 0.065 13.3 0.0 3.9 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 GAM19566.1 - 6.5e-07 29.5 0.0 0.035 14.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 GAM19566.1 - 6.5e-07 28.9 0.1 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 GAM19566.1 - 7.2e-07 29.5 0.1 0.0011 19.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM19566.1 - 1.5e-06 27.9 0.1 0.12 12.0 0.1 3.5 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.1 GAM19566.1 - 1.6e-06 28.0 0.0 0.022 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 GAM19566.1 - 2.4e-06 26.8 0.4 0.0096 15.1 0.1 2.9 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 GAM19566.1 - 6.6e-06 25.3 0.2 0.00043 19.4 0.0 3.3 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM19566.1 - 1.3e-05 24.8 0.4 0.18 11.5 0.2 2.9 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 GAM19566.1 - 3.7e-05 22.9 0.1 0.019 14.0 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 GAM19566.1 - 7.4e-05 22.6 0.1 0.52 10.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 GAM19566.1 - 0.00017 21.8 0.7 1.2 9.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_2 PF07724.9 GAM19566.1 - 0.00038 20.4 0.0 0.03 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 GAM19566.1 - 0.00042 19.1 0.1 0.078 11.6 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 GAM19566.1 - 0.00043 19.8 0.0 0.1 12.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 GAM19566.1 - 0.0052 16.8 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain CDC48_N PF02359.13 GAM19566.1 - 0.006 16.4 0.0 0.59 10.1 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain NB-ARC PF00931.17 GAM19566.1 - 0.0077 15.1 0.0 2.2 7.0 0.0 2.8 2 1 1 3 3 3 1 NB-ARC domain T2SE PF00437.15 GAM19566.1 - 0.0087 14.9 0.2 2.3 7.0 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_24 PF13479.1 GAM19566.1 - 0.0089 15.6 0.3 0.24 10.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 GAM19566.1 - 0.0095 15.1 0.6 3.3 6.8 0.2 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 GAM19566.1 - 0.011 15.7 4.1 1.9 8.4 0.0 3.3 4 0 0 4 4 2 0 AAA domain Arch_ATPase PF01637.13 GAM19566.1 - 0.018 14.7 0.0 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 GAM19566.1 - 0.018 14.5 0.0 0.96 9.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM19566.1 - 0.024 14.9 9.4 0.97 9.7 0.0 3.6 2 2 0 2 2 2 0 AAA domain CDC48_2 PF02933.12 GAM19566.1 - 0.031 13.9 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_10 PF12846.2 GAM19566.1 - 0.037 13.4 0.3 6.3 6.1 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain ATP-synt_C PF00137.16 GAM19567.1 - 2.3e-32 110.6 26.7 4.5e-16 58.5 4.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 GAM19567.1 - 0.004 16.6 0.5 0.027 14.0 0.3 2.2 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Vma12 PF11712.3 GAM19567.1 - 2.3 7.8 4.1 10 5.8 2.8 2.0 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_C PF00137.16 GAM19568.1 - 1.1e-24 86.1 36.0 9.4e-14 51.0 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CBS PF00571.23 GAM19569.1 - 1.6e-35 120.5 4.8 3.8e-12 45.8 0.4 4.3 4 0 0 4 4 4 4 CBS domain Mic1 PF07035.7 GAM19569.1 - 0.021 14.1 0.1 0.053 12.8 0.0 1.6 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Pro-kuma_activ PF09286.6 GAM19570.1 - 3.3e-31 108.2 0.1 5.1e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Methyltransf_31 PF13847.1 GAM19571.1 - 3.6e-10 39.6 0.5 5.8e-10 38.9 0.3 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM19571.1 - 5.3e-09 36.6 0.0 8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM19571.1 - 4.8e-08 33.3 0.0 9.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM19571.1 - 5.9e-07 29.5 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM19571.1 - 8.7e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 GAM19571.1 - 9.7e-06 24.7 0.0 1.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 GAM19571.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM19571.1 - 1.9e-05 24.4 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAM19571.1 - 2.9e-05 23.7 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAM19571.1 - 6.7e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 GAM19571.1 - 9.1e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 GAM19571.1 - 0.00012 22.5 0.1 0.00035 20.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAM19571.1 - 0.00013 21.1 0.2 0.00042 19.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAM19571.1 - 0.00014 21.3 0.2 0.0003 20.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain DOT1 PF08123.8 GAM19571.1 - 0.00048 19.4 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 N6_N4_Mtase PF01555.13 GAM19571.1 - 0.00069 19.1 0.1 0.0014 18.1 0.0 1.5 2 0 0 2 2 2 1 DNA methylase Ubie_methyltran PF01209.13 GAM19571.1 - 0.0027 16.8 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 GAM19571.1 - 0.0047 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 GAM19571.1 - 0.0063 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_8 PF05148.10 GAM19571.1 - 0.045 13.3 0.7 0.061 12.9 0.0 1.5 2 0 0 2 2 1 0 Hypothetical methyltransferase Methyltransf_15 PF09445.5 GAM19571.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 GAM19571.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein ETC_C1_NDUFA4 PF04800.7 GAM19572.1 - 3.4e-27 94.2 0.5 8.7e-27 92.9 0.0 1.7 2 0 0 2 2 2 1 ETC complex I subunit conserved region NAD_binding_4 PF07993.7 GAM19572.1 - 0.076 11.9 0.3 0.12 11.2 0.2 1.4 1 1 0 1 1 1 0 Male sterility protein Med3 PF11593.3 GAM19572.1 - 0.13 11.4 5.5 0.17 11.0 3.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TSA PF03249.8 GAM19572.1 - 3 6.2 6.6 3.8 5.9 4.6 1.1 1 0 0 1 1 1 0 Type specific antigen SRP54 PF00448.17 GAM19573.1 - 6.9e-53 179.0 2.5 6.9e-53 179.0 1.7 2.5 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 GAM19573.1 - 9.6e-49 166.2 19.3 1.3e-48 165.7 13.4 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 GAM19573.1 - 7.3e-08 32.3 0.0 3.6e-07 30.1 0.0 2.3 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 GAM19573.1 - 1.5e-06 28.3 0.1 5.5e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 GAM19573.1 - 1.1e-05 24.8 0.6 3.6e-05 23.2 0.4 1.9 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 GAM19573.1 - 6.9e-05 22.5 0.1 0.00019 21.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 GAM19573.1 - 7.8e-05 21.5 1.5 8.1e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 ArgK protein NTPase_1 PF03266.10 GAM19573.1 - 0.00022 20.9 0.2 0.031 13.9 0.1 2.7 1 1 0 1 1 1 1 NTPase MobB PF03205.9 GAM19573.1 - 0.00038 20.1 0.4 0.073 12.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 GAM19573.1 - 0.0011 18.4 2.1 0.0036 16.7 1.4 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAM19573.1 - 0.011 15.7 0.0 0.039 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain VirC1 PF07015.6 GAM19573.1 - 0.032 13.2 0.1 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 VirC1 protein SPOUT_MTase PF02590.12 GAM19573.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase 2OG-FeII_Oxy_3 PF13640.1 GAM19574.1 - 6.8e-21 74.6 0.0 1.8e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM19574.1 - 1.2e-06 28.7 0.0 2.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM19574.1 - 0.00015 21.3 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 GAM19574.1 - 0.0061 16.8 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase RRM_1 PF00076.17 GAM19575.1 - 7.4e-19 67.1 0.1 1.6e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19575.1 - 2.1e-12 46.8 0.0 3.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19575.1 - 7.2e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2246 PF10229.4 GAM19576.1 - 1.2e-24 87.0 0.0 1.4e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) GrpE PF01025.14 GAM19577.1 - 3.3e-48 163.3 4.6 4.2e-48 163.0 3.2 1.1 1 0 0 1 1 1 1 GrpE Orn_Arg_deC_N PF02784.11 GAM19577.1 - 0.056 12.6 1.3 0.54 9.3 0.2 2.5 1 1 1 3 3 3 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain ALMT PF11744.3 GAM19577.1 - 0.24 10.0 1.0 0.29 9.7 0.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3484 PF11983.3 GAM19577.1 - 0.9 10.4 4.6 2 9.3 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) TBPIP PF07106.8 GAM19577.1 - 1.8 8.0 8.9 1.2 8.6 4.3 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Alg6_Alg8 PF03155.10 GAM19578.1 - 1.3e-143 479.2 46.4 1.6e-143 478.9 32.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF1129 PF06570.6 GAM19578.1 - 1.8 7.7 7.1 1.8 7.7 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Apc1 PF12859.2 GAM19579.1 - 2.6e-10 40.4 2.6 5.4e-10 39.4 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 GAM19579.1 - 4.1e-07 29.8 17.6 0.11 12.7 0.1 6.2 6 0 0 6 6 6 3 Proteasome/cyclosome repeat SSP160 PF06933.6 GAM19580.1 - 0.054 11.4 9.7 0.086 10.8 6.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4175 PF13779.1 GAM19580.1 - 0.14 9.8 12.3 0.18 9.4 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mucin PF01456.12 GAM19580.1 - 0.47 10.2 22.1 0.17 11.6 12.5 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 GAM19580.1 - 0.77 9.5 13.7 0.16 11.6 7.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) G-alpha PF00503.15 GAM19581.1 - 1.5e-27 96.3 0.1 1.8e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit AAA_23 PF13476.1 GAM19581.1 - 0.016 15.5 0.1 0.064 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 GAM19581.1 - 0.026 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF3584 PF12128.3 GAM19581.1 - 0.061 10.6 0.3 0.1 9.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 GAM19581.1 - 0.14 11.6 0.4 0.96 8.9 0.1 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PP2C PF00481.16 GAM19582.1 - 2.6e-70 236.7 0.0 2.6e-70 236.7 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C CAF-1_p150 PF11600.3 GAM19582.1 - 7.4e-06 25.5 38.8 7.4e-06 25.5 26.9 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1788 PF08747.6 GAM19582.1 - 0.22 11.3 3.5 0.65 9.8 1.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) V_ATPase_I PF01496.14 GAM19582.1 - 0.99 7.1 8.9 1.5 6.6 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M4 PF01447.13 GAM19582.1 - 1.4 9.0 5.2 1.3 9.1 0.0 2.8 2 1 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain Pkinase PF00069.20 GAM19583.1 - 1.4e-67 227.5 0.0 3e-45 154.3 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19583.1 - 9.1e-27 93.7 0.0 9.9e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase FNIP PF05725.7 GAM19583.1 - 7.1e-11 41.8 1.2 2.9e-06 27.1 0.1 2.7 1 1 1 2 2 2 2 FNIP Repeat Kinase-like PF14531.1 GAM19583.1 - 0.00051 19.0 0.1 0.0022 17.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM19583.1 - 0.0015 18.3 0.1 0.0035 17.0 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3505 PF12013.3 GAM19583.1 - 0.023 14.9 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Kdo PF06293.9 GAM19583.1 - 0.031 13.3 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FNIP PF05725.7 GAM19584.1 - 1.9e-34 117.3 1.7 1.2e-05 25.1 0.1 10.4 8 2 2 10 10 10 9 FNIP Repeat LCM PF04072.9 GAM19585.1 - 8.9e-14 51.4 0.0 1.7e-13 50.5 0.0 1.2 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DNase_II PF03265.10 GAM19586.1 - 0.00017 20.7 0.1 0.00018 20.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II SVM_signal PF12113.3 GAM19586.1 - 0.1 12.4 1.9 0.18 11.6 1.3 1.3 1 0 0 1 1 1 0 SVM protein signal sequence Band_7 PF01145.20 GAM19587.1 - 1.2e-07 31.7 1.8 1.2e-07 31.7 1.3 2.3 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 GAM19587.1 - 0.00081 18.9 0.3 0.0016 17.9 0.2 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Myosin_head PF00063.16 GAM19588.1 - 3.3e-255 848.4 9.5 5.2e-255 847.7 6.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM19588.1 - 4.4e-42 143.6 0.0 7.7e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 GAM19588.1 - 1.2e-07 30.6 10.2 0.0006 19.2 0.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Zeta_toxin PF06414.7 GAM19588.1 - 0.00035 19.7 0.0 0.0008 18.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 GAM19588.1 - 0.0023 18.0 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM19588.1 - 0.0059 16.9 0.5 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM19588.1 - 0.0059 16.6 0.0 0.13 12.2 0.0 3.1 5 0 0 5 5 5 1 AAA ATPase domain ALO PF04030.9 GAM19588.1 - 0.011 15.3 0.4 0.037 13.6 0.3 1.9 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Hpr_kinase_C PF07475.7 GAM19588.1 - 0.022 14.0 0.3 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 GAM19588.1 - 0.03 15.1 0.1 0.2 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM19588.1 - 0.11 12.8 0.3 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter ARD PF03079.9 GAM19589.1 - 1.4e-43 148.5 0.2 1.7e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 GAM19589.1 - 9.6e-10 37.8 0.0 1.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 GAM19589.1 - 0.00018 21.1 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 GAM19589.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 GAM19589.1 - 0.031 13.7 0.0 0.34 10.3 0.0 1.9 1 1 1 2 2 2 0 Cupin-like domain EF-hand_7 PF13499.1 GAM19590.1 - 1.4e-05 25.1 0.3 1.4e-05 25.1 0.2 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM19590.1 - 9.1e-05 21.6 0.1 0.00022 20.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAM19590.1 - 0.0002 20.9 0.3 0.00093 18.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 GAM19590.1 - 0.00026 20.0 0.0 0.00062 18.8 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 GAM19590.1 - 0.0017 17.9 0.1 0.039 13.5 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair MIT PF04212.13 GAM19590.1 - 0.0046 16.8 0.9 0.21 11.4 0.3 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 GAM19590.1 - 0.038 13.6 0.3 0.13 11.9 0.2 1.9 1 1 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 GAM19590.1 - 0.067 13.5 0.4 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Zip PF02535.17 GAM19590.1 - 3 6.7 8.9 4.3 6.2 6.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DEAD PF00270.24 GAM19591.1 - 1.4e-45 154.7 0.1 3.1e-45 153.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM19591.1 - 4.8e-21 74.4 0.0 1.4e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM19591.1 - 1.3e-16 59.9 0.1 3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 GAM19591.1 - 0.00026 20.8 0.9 0.00089 19.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM19591.1 - 0.0016 18.5 0.0 0.0077 16.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF3592 PF12158.3 GAM19591.1 - 0.0068 16.2 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Helicase_RecD PF05127.9 GAM19591.1 - 0.0099 15.5 0.0 0.039 13.6 0.0 2.0 1 0 0 1 1 1 1 Helicase CRM1_C PF08767.6 GAM19592.1 - 1.1e-108 362.9 12.2 1.1e-108 362.9 8.4 3.3 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 GAM19592.1 - 7e-35 120.1 6.5 7e-35 120.1 4.5 3.9 4 3 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAM19592.1 - 2e-14 53.2 1.7 4.6e-14 52.0 0.1 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 GAM19592.1 - 0.0077 16.2 0.0 14 6.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM19592.1 - 0.026 14.8 0.7 2.6 8.4 0.0 4.2 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region UCH PF00443.24 GAM19592.1 - 0.13 11.3 2.7 0.18 10.8 0.2 2.6 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase TIG PF01833.19 GAM19593.1 - 3.9e-58 193.4 134.8 1.1e-09 38.1 0.4 15.7 16 0 0 16 16 16 13 IPT/TIG domain DNase_II PF03265.10 GAM19593.1 - 1e-19 70.7 3.4 2.4e-13 49.8 0.2 2.7 3 0 0 3 3 3 2 Deoxyribonuclease II Qn_am_d_aIII PF09099.5 GAM19593.1 - 0.003 17.8 4.7 0.54 10.6 0.0 3.7 4 0 0 4 4 4 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III PBP1_TM PF14812.1 GAM19594.1 - 2.4 8.5 16.6 0.72 10.1 6.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_6 PF13516.1 GAM19595.1 - 4.2e-06 26.2 15.1 1 9.6 0.4 6.4 6 1 1 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 GAM19595.1 - 7.5e-06 25.4 12.3 0.0084 15.7 3.3 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM19595.1 - 0.00063 19.4 6.9 0.0013 18.4 1.0 2.9 2 1 0 2 2 2 1 Leucine rich repeat GATA PF00320.22 GAM19596.1 - 1.2e-10 40.4 4.2 2.7e-10 39.4 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger Cytochrome_C7 PF14522.1 GAM19596.1 - 0.076 12.6 1.3 0.14 11.7 0.9 1.5 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 GAM19596.1 - 0.13 12.6 2.3 0.2 11.9 1.6 1.5 1 1 0 1 1 1 0 Cytochrome c3 zf-C2H2_3 PF13878.1 GAM19596.1 - 0.21 11.1 1.7 2 8.0 0.0 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO NIF PF03031.13 GAM19597.1 - 6e-17 61.7 0.1 1.5e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Plasmodium_Vir PF05795.6 GAM19597.1 - 0.00028 20.2 5.2 0.00035 19.8 3.6 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein FimP PF09766.4 GAM19597.1 - 0.0055 15.8 11.2 0.012 14.7 7.8 1.5 1 0 0 1 1 1 1 Fms-interacting protein Nucleoside_tran PF01733.13 GAM19597.1 - 0.03 13.4 2.4 0.044 12.9 1.6 1.1 1 0 0 1 1 1 0 Nucleoside transporter CDC45 PF02724.9 GAM19597.1 - 0.048 11.7 7.0 0.067 11.2 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4337 PF14235.1 GAM19597.1 - 0.13 12.0 9.0 0.11 12.3 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF3899 PF13038.1 GAM19597.1 - 0.13 12.3 3.0 0.17 12.0 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) Folate_carrier PF01770.13 GAM19597.1 - 0.15 10.5 4.1 0.2 10.1 2.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier WASH-7_C PF14746.1 GAM19597.1 - 0.16 11.5 6.2 0.28 10.7 4.3 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DUF4407 PF14362.1 GAM19597.1 - 0.19 10.6 7.0 0.36 9.7 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.8 GAM19597.1 - 0.29 9.9 14.1 0.38 9.5 9.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FAM176 PF14851.1 GAM19597.1 - 0.38 10.4 3.0 0.68 9.6 2.1 1.4 1 0 0 1 1 1 0 FAM176 family AAA_11 PF13086.1 GAM19597.1 - 0.59 9.6 10.0 0.095 12.2 4.1 1.7 2 1 0 2 2 2 0 AAA domain DUF2201_N PF13203.1 GAM19597.1 - 0.63 9.1 7.7 1.1 8.4 5.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_S49_N PF08496.5 GAM19597.1 - 0.72 9.6 12.6 0.53 10.0 6.7 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal EIIBC-GUT_N PF03612.9 GAM19597.1 - 0.85 9.2 6.9 1.5 8.4 4.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3464 PF11947.3 GAM19597.1 - 1.9 7.9 5.2 3.6 7.0 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) ETRAMP PF09716.5 GAM19597.1 - 3.2 7.7 6.0 13 5.8 4.1 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) AIF_C PF14721.1 GAM19597.1 - 7.9 6.7 8.9 17 5.6 6.2 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF866 PF05907.8 GAM19598.1 - 9.5e-43 145.4 3.2 1.1e-42 145.3 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-PHD-like PF15446.1 GAM19598.1 - 0.018 14.3 1.3 0.041 13.1 0.9 1.6 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zinc_ribbon_5 PF13719.1 GAM19598.1 - 0.42 10.2 2.2 10 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAM19598.1 - 1.1 9.0 4.2 10 5.9 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon domain ACBP PF00887.14 GAM19599.1 - 6e-25 86.7 3.1 6.5e-25 86.6 2.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Mito_carr PF00153.22 GAM19600.1 - 1.9e-62 206.9 4.0 4.1e-20 71.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Form-deh_trans PF09163.6 GAM19600.1 - 8.9 5.8 6.1 0.88 9.1 0.2 2.3 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane Sec16_C PF12931.2 GAM19601.1 - 2e-42 145.8 0.0 6.3e-42 144.2 0.0 1.9 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 GAM19601.1 - 6.5e-17 61.5 0.0 6.5e-17 61.5 0.0 3.0 2 1 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region bZIP_1 PF00170.16 GAM19602.1 - 2.3e-08 33.8 4.4 2.3e-08 33.8 3.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM19602.1 - 3.5e-07 29.9 7.5 3.5e-07 29.9 5.2 3.6 4 0 0 4 4 4 1 Basic region leucine zipper DUF3439 PF11921.3 GAM19602.1 - 0.13 11.9 2.2 0.47 10.1 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PDCD2_C PF04194.8 GAM19603.1 - 4.3e-26 91.4 10.5 4.3e-26 91.4 7.3 3.0 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.13 GAM19603.1 - 2.9e-05 23.8 14.6 2.9e-05 23.8 10.1 3.2 3 1 0 3 3 3 1 MYND finger NOT2_3_5 PF04153.13 GAM19605.1 - 2.3e-30 105.2 0.5 2.3e-30 105.2 0.3 3.3 3 2 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Adenine_glyco PF03352.8 GAM19606.1 - 2.6e-71 238.8 0.0 4.2e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Methyladenine glycosylase Haemadin PF09065.5 GAM19606.1 - 2 8.0 4.1 0.92 9.1 0.7 1.9 2 0 0 2 2 2 0 Haemadin Tctex-1 PF03645.8 GAM19607.1 - 1.1e-35 121.5 1.0 1.3e-35 121.2 0.7 1.0 1 0 0 1 1 1 1 Tctex-1 family MFS_1 PF07690.11 GAM19608.1 - 1.1e-23 83.5 72.9 3.2e-23 82.0 25.4 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2368 PF10166.4 GAM19608.1 - 3.3e-22 78.4 1.5 1.8e-21 76.0 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2368) eIF3g PF12353.3 GAM19609.1 - 0.024 14.5 1.9 0.064 13.1 1.3 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G E1-E2_ATPase PF00122.15 GAM19612.1 - 9.4e-55 185.1 0.2 9.4e-55 185.1 0.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM19612.1 - 1.2e-35 122.7 10.4 1.2e-35 122.7 7.2 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM19612.1 - 2.3e-22 80.4 0.0 4.4e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM19612.1 - 7.2e-09 36.0 0.0 3.3e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM19612.1 - 8.8e-09 34.7 0.0 2.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 GAM19612.1 - 8.3e-08 32.0 0.1 1.2e-06 28.3 0.0 2.7 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM19612.1 - 1.7e-07 31.1 2.1 5e-05 22.9 0.8 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase GpcrRhopsn4 PF10192.4 GAM19613.1 - 1.9e-77 259.9 19.5 2.6e-77 259.4 13.5 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 GAM19613.1 - 1e-05 24.6 15.4 1.9e-05 23.8 10.7 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor Syndecan PF01034.15 GAM19613.1 - 0.036 13.6 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Syndecan domain MscS_TM PF12794.2 GAM19613.1 - 4 5.9 14.8 6 5.3 2.2 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 zf-H2C2_2 PF13465.1 GAM19615.1 - 8.7e-16 57.3 35.7 4.8e-07 29.7 1.7 5.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 GAM19615.1 - 1.3e-14 53.5 44.2 8.6e-05 22.6 1.2 5.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM19615.1 - 2.1e-06 27.6 48.6 0.0034 17.6 0.2 6.6 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.2 GAM19615.1 - 3.2e-05 23.9 10.0 0.83 9.9 0.9 5.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type PAP_central PF04928.12 GAM19615.1 - 0.03 13.1 6.5 0.059 12.1 4.5 1.5 1 0 0 1 1 1 0 Poly(A) polymerase central domain Med15 PF09606.5 GAM19615.1 - 0.14 10.3 81.3 0.18 9.9 56.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4647 PF15504.1 GAM19615.1 - 0.79 8.5 29.5 2 7.2 20.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) LMBR1 PF04791.11 GAM19615.1 - 4.7 5.6 4.8 6.3 5.2 3.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Sod_Fe_C PF02777.13 GAM19616.1 - 4.6e-39 132.5 0.1 8.4e-39 131.6 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAM19616.1 - 1.2e-29 102.4 1.3 1.3e-29 102.2 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain LIM PF00412.17 GAM19617.1 - 1.9e-11 43.8 9.5 2.9e-11 43.2 6.6 1.2 1 0 0 1 1 1 1 LIM domain DUF1451 PF07295.6 GAM19617.1 - 0.48 10.2 3.4 1.3 8.7 0.4 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1451) BPL_LplA_LipB PF03099.14 GAM19618.1 - 7.9e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GFA PF04828.9 GAM19619.1 - 0.0073 16.2 2.3 0.0073 16.2 1.6 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PI3_PI4_kinase PF00454.22 GAM19620.1 - 2.5e-20 72.9 1.9 6e-20 71.7 1.3 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase bZIP_1 PF00170.16 GAM19621.1 - 1.8e-06 27.8 11.8 1.8e-06 27.8 8.2 3.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM19621.1 - 0.0015 18.2 17.7 0.0015 18.2 12.2 3.5 2 2 0 2 2 2 1 Basic region leucine zipper Erv26 PF04148.8 GAM19622.1 - 3.2e-48 163.9 23.1 6e-48 163.0 16.0 1.4 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 IncA PF04156.9 GAM19622.1 - 2.3 7.7 5.9 0.51 9.9 1.1 2.0 1 1 0 1 1 1 0 IncA protein Cpn60_TCP1 PF00118.19 GAM19623.1 - 1.5e-145 485.5 1.7 1.7e-145 485.3 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nse4-Nse3_bdg PF15412.1 GAM19623.1 - 0.031 14.0 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE Xan_ur_permease PF00860.15 GAM19624.1 - 5.9e-82 275.2 45.9 7.2e-82 274.9 31.8 1.1 1 0 0 1 1 1 1 Permease family DUF2157 PF09925.4 GAM19624.1 - 6.4 6.3 15.7 3.8 7.0 3.1 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) FMN_red PF03358.10 GAM19625.1 - 1.3e-28 99.4 0.0 1.8e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM19625.1 - 2.4e-05 23.9 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold POP1 PF06978.6 GAM19626.1 - 8.4e-26 90.7 4.5 8.4e-26 90.7 3.1 2.0 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 GAM19626.1 - 1.6e-25 88.7 0.4 6.8e-25 86.7 0.3 2.2 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 GAM19626.1 - 8.4e-05 22.0 0.0 0.37 10.1 0.0 2.3 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain Ras PF00071.17 GAM19627.1 - 2.5e-57 192.7 0.0 2.8e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19627.1 - 3.5e-20 72.6 0.0 5.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19627.1 - 4.3e-09 35.8 0.0 4.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM19627.1 - 7e-07 28.8 0.2 2.1e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM19627.1 - 3.7e-05 23.6 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM19627.1 - 0.013 14.1 0.1 1.2 7.7 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 GAM19627.1 - 0.072 11.9 0.0 6.6 5.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DAO PF01266.19 GAM19628.1 - 1.4e-52 178.8 0.0 1.6e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM19628.1 - 6.8e-09 34.6 0.5 0.00043 18.8 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 GAM19628.1 - 3.5e-08 32.7 0.7 3.6e-05 22.8 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAM19628.1 - 7.3e-08 32.5 0.1 0.006 16.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM19628.1 - 8e-08 31.5 0.5 0.0001 21.3 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAM19628.1 - 2.9e-06 27.2 0.0 7.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM19628.1 - 1.8e-05 23.9 0.0 4.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 GAM19628.1 - 5.7e-05 23.2 0.1 0.099 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 GAM19628.1 - 6.7e-05 21.3 0.5 0.22 9.8 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_binding_3 PF01494.14 GAM19628.1 - 7.4e-05 21.9 0.1 0.00016 20.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 GAM19628.1 - 0.00014 21.1 0.1 0.0002 20.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 GAM19628.1 - 0.0023 17.6 0.0 0.0054 16.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 GAM19628.1 - 0.0082 16.5 0.9 0.047 14.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM19628.1 - 0.0094 14.9 0.2 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 GAM19628.1 - 0.013 15.3 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 GAM19628.1 - 0.082 11.8 0.9 1.7 7.4 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Proteasome PF00227.21 GAM19629.1 - 1.2e-48 164.9 0.3 1.5e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_S5 PF00333.15 GAM19630.1 - 1.1e-28 98.7 2.6 1.9e-28 97.9 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 GAM19630.1 - 4.1e-23 80.4 0.1 7.1e-23 79.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RNB PF00773.14 GAM19631.1 - 1.9e-96 323.1 0.0 3.2e-96 322.4 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 GAM19631.1 - 2.5e-14 53.5 2.6 2.5e-14 53.5 1.8 2.2 2 0 0 2 2 2 1 PIN domain Got1 PF04178.7 GAM19632.1 - 2.7e-25 88.7 22.0 3.1e-25 88.5 15.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YwiC PF14256.1 GAM19632.1 - 1.5 8.8 10.1 2.5 8.2 6.9 1.4 1 1 0 1 1 1 0 YwiC-like protein TMEM223 PF14640.1 GAM19633.1 - 8e-06 25.8 3.4 0.0028 17.5 0.0 3.3 2 1 1 3 3 3 2 Transmembrane protein 223 Pex14_N PF04695.8 GAM19633.1 - 0.00036 20.5 1.4 0.00075 19.5 0.9 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Inhibitor_I71 PF12628.2 GAM19633.1 - 0.00064 19.4 3.1 0.00064 19.4 2.2 1.6 2 0 0 2 2 2 1 Falstatin, cysteine peptidase inhibitor DivIC PF04977.10 GAM19633.1 - 0.12 11.8 12.6 1.7 8.1 0.9 2.5 2 0 0 2 2 2 0 Septum formation initiator RNA_pol_Rpb6 PF01192.17 GAM19634.1 - 2.5e-20 71.9 0.1 3.5e-20 71.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Cupin_8 PF13621.1 GAM19636.1 - 1.5e-06 27.9 1.4 0.00022 20.7 0.0 3.1 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 GAM19636.1 - 0.011 15.9 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase ParA PF10609.4 GAM19637.1 - 6.1e-37 125.3 0.3 1.2e-36 124.4 0.2 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAM19637.1 - 8e-14 51.4 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM19637.1 - 7.1e-09 35.7 0.0 6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 GAM19637.1 - 5e-08 32.4 0.1 3.9e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.6 GAM19637.1 - 3e-05 23.2 0.0 4.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 GAM19637.1 - 5.8e-05 22.2 0.6 0.013 14.6 0.1 3.0 2 1 0 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 GAM19637.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 GAM19637.1 - 0.03 13.9 0.7 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 GAM19638.1 - 3.3e-62 206.8 4.9 2e-23 82.4 0.9 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM19638.1 - 6.8e-60 196.0 15.2 2.8e-09 36.3 0.2 9.8 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 GAM19638.1 - 1.9e-44 149.2 6.1 2.5e-08 34.2 0.1 7.6 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19638.1 - 5.3e-41 134.5 8.8 9.6e-07 28.4 0.1 9.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 GAM19638.1 - 1.5e-40 136.2 6.6 9.3e-10 38.4 0.1 7.1 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Homeobox PF00046.24 GAM19638.1 - 3e-18 65.1 0.9 3e-18 65.1 0.6 2.1 2 0 0 2 2 2 1 Homeobox domain SR-25 PF10500.4 GAM19638.1 - 0.0019 17.7 7.1 0.0019 17.7 4.9 3.4 2 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Gelsolin PF00626.17 GAM19639.1 - 3.3e-32 110.0 1.4 4.3e-11 42.3 0.0 5.8 5 0 0 5 5 5 5 Gelsolin repeat Complex1_LYR PF05347.10 GAM19640.1 - 0.0054 16.4 0.3 0.0095 15.7 0.2 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM19640.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 1 1 0 1 1 1 0 Complex1_LYR-like FNIP PF05725.7 GAM19641.1 - 1.1e-15 57.2 11.3 4.7e-05 23.2 0.0 7.3 5 1 4 9 9 9 6 FNIP Repeat RTBV_P46 PF06216.6 GAM19641.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein AAA_21 PF13304.1 GAM19642.1 - 2.5e-05 24.4 0.4 2.5e-05 24.4 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM19642.1 - 0.0013 18.7 0.2 0.0056 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 GAM19642.1 - 0.0044 17.8 2.3 0.32 11.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 GAM19642.1 - 0.034 13.8 1.9 0.074 12.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase SAM_PNT PF02198.11 GAM19642.1 - 0.046 13.4 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain NACHT PF05729.7 GAM19642.1 - 0.048 13.3 0.0 0.3 10.7 0.0 2.2 1 1 0 1 1 1 0 NACHT domain AAA PF00004.24 GAM19642.1 - 0.063 13.4 0.1 0.21 11.8 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM19642.1 - 0.087 12.9 0.5 0.58 10.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain Gelsolin PF00626.17 GAM19642.1 - 0.12 12.1 0.6 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Gelsolin repeat AAA_18 PF13238.1 GAM19642.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.9 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAM19642.1 - 0.26 11.5 0.1 0.26 11.5 0.0 3.1 4 1 0 4 4 4 0 AAA domain AAA_11 PF13086.1 GAM19642.1 - 0.69 9.4 4.8 7.1 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain F-box-like PF12937.2 GAM19645.1 - 0.079 12.7 0.7 0.16 11.7 0.1 1.9 2 0 0 2 2 2 0 F-box-like HC2 PF07382.6 GAM19647.1 - 0.021 14.7 13.4 0.035 13.9 9.3 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 CENP-T PF15511.1 GAM19647.1 - 0.14 11.4 10.2 0.22 10.7 7.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 GAM19647.1 - 0.22 9.4 8.9 0.35 8.7 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 GAM19647.1 - 0.47 10.0 12.1 1.2 8.6 8.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Herpes_DNAp_acc PF04929.7 GAM19647.1 - 2.2 7.1 8.0 4 6.2 5.5 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 GAM19647.1 - 2.6 5.9 7.0 4 5.3 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Alpha_kinase PF02816.13 GAM19648.1 - 1e-22 80.7 0.7 1.3e-22 80.3 0.5 1.1 1 0 0 1 1 1 1 Alpha-kinase family G-patch PF01585.18 GAM19648.1 - 0.24 11.2 1.1 0.45 10.3 0.8 1.5 1 0 0 1 1 1 0 G-patch domain MP PF01107.13 GAM19649.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Viral movement protein (MP) BAR PF03114.13 GAM19650.1 - 4e-12 46.1 3.8 6.5e-12 45.4 2.6 1.3 1 0 0 1 1 1 1 BAR domain EcoR124_C PF12008.3 GAM19650.1 - 0.00045 19.5 5.5 0.15 11.1 1.7 2.2 2 0 0 2 2 2 2 Type I restriction and modification enzyme - subunit R C terminal Occludin_ELL PF07303.8 GAM19650.1 - 0.16 12.7 8.3 12 6.6 3.7 2.4 2 0 0 2 2 2 0 Occludin homology domain Phage_GP20 PF06810.6 GAM19650.1 - 0.28 10.6 8.9 0.5 9.7 5.7 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 Prp19_bind PF06991.6 GAM19651.1 - 1.7e-53 181.7 45.5 1.7e-53 181.7 31.6 2.5 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain 5_nucleotid_C PF02872.13 GAM19652.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain RhoGAP PF00620.22 GAM19653.1 - 5e-33 113.8 0.0 1.1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.6 GAM19653.1 - 0.00014 21.4 1.3 0.79 9.9 0.0 5.2 5 0 0 5 5 5 1 Two component regulator propeller Endonuc-BsobI PF09194.5 GAM19653.1 - 0.0061 15.5 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease BsobI Cytochrom_D1 PF02239.11 GAM19653.1 - 0.052 11.8 4.0 0.43 8.8 0.3 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain G8 PF10162.4 GAM19655.1 - 5.5e-19 68.2 0.2 2.6e-18 66.0 0.0 2.2 2 0 0 2 2 2 1 G8 domain Beta_helix PF13229.1 GAM19655.1 - 0.00065 19.4 12.0 0.082 12.6 0.2 4.2 2 1 0 3 3 3 2 Right handed beta helix region adh_short PF00106.20 GAM19660.1 - 1.6e-31 109.4 1.9 2.4e-31 108.9 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM19660.1 - 4.5e-17 62.2 0.9 6.6e-17 61.7 0.6 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAM19660.1 - 2e-06 26.6 1.6 1.2e-05 24.1 1.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM19660.1 - 0.0015 18.0 0.7 0.0025 17.2 0.2 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM19660.1 - 0.0015 17.5 0.0 0.042 12.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 GAM19660.1 - 0.011 14.7 0.4 0.012 14.6 0.3 1.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM19660.1 - 0.017 14.9 0.0 0.059 13.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.13 GAM19660.1 - 0.039 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF87 PF01935.12 GAM19660.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 Cofilin_ADF PF00241.15 GAM19662.1 - 6.8e-07 29.2 0.0 8.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Kinesin PF00225.18 GAM19663.1 - 6.7e-108 360.3 0.0 6.7e-108 360.3 0.0 2.7 3 1 1 4 4 4 1 Kinesin motor domain PH PF00169.24 GAM19663.1 - 1.5e-10 41.2 2.1 9.7e-10 38.5 1.1 2.7 2 0 0 2 2 2 1 PH domain DUF3694 PF12473.3 GAM19663.1 - 2.7e-07 30.3 4.1 4.2e-06 26.4 0.0 4.4 3 1 0 3 3 3 1 Kinesin protein FHA PF00498.21 GAM19663.1 - 3.4e-06 27.0 0.1 2.9e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 FHA domain PH_8 PF15409.1 GAM19663.1 - 0.00081 19.4 3.7 0.0013 18.7 0.3 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain KIF1B PF12423.3 GAM19663.1 - 0.0052 16.7 2.7 0.076 13.0 0.1 3.3 2 0 0 2 2 2 1 Kinesin protein 1B RhoGAP PF00620.22 GAM19664.1 - 4.8e-30 104.1 0.2 2.4e-29 101.9 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain Vac_Fusion PF02346.11 GAM19664.1 - 0.14 11.6 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein RRM_1 PF00076.17 GAM19665.1 - 4.6e-08 32.5 0.2 8.5e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19665.1 - 5.9e-05 22.9 0.1 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19665.1 - 0.032 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF848 PF05852.6 GAM19665.1 - 0.35 10.7 4.8 1 9.1 0.1 2.4 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SH3_9 PF14604.1 GAM19666.1 - 3.2e-27 93.8 3.0 4.6e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 GAM19666.1 - 1.5e-23 82.0 0.7 3.2e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAM19666.1 - 8.5e-23 79.4 2.6 1.2e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain DivIC PF04977.10 GAM19666.1 - 0.012 15.1 23.9 0.06 12.8 1.5 4.3 4 0 0 4 4 4 0 Septum formation initiator Seryl_tRNA_N PF02403.17 GAM19666.1 - 0.025 14.5 25.6 1.3 9.0 5.0 4.1 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Phasin PF05597.6 GAM19666.1 - 0.029 14.1 0.2 0.029 14.1 0.1 3.1 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF2937 PF11157.3 GAM19666.1 - 0.067 12.5 0.7 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) IncA PF04156.9 GAM19666.1 - 0.13 11.8 19.5 0.15 11.6 0.2 3.0 2 1 1 3 3 3 0 IncA protein HR1 PF02185.11 GAM19666.1 - 2 8.2 27.6 2.5 7.8 5.1 3.9 3 1 1 4 4 4 0 Hr1 repeat Uds1 PF15456.1 GAM19666.1 - 4.3 7.3 21.2 7 6.6 3.5 3.2 2 1 1 3 3 3 0 Up-regulated During Septation SlyX PF04102.7 GAM19666.1 - 8.4 6.8 15.2 0.13 12.6 0.3 3.8 2 1 1 4 4 4 0 SlyX Sulfotransfer_1 PF00685.22 GAM19667.1 - 1.4e-18 67.1 2.9 2.3e-18 66.4 0.2 2.4 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 GAM19667.1 - 0.00041 21.3 0.0 0.0018 19.2 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 GAM19667.1 - 0.049 13.2 0.7 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase family Ion_trans PF00520.26 GAM19667.1 - 0.055 12.7 0.3 0.15 11.2 0.1 1.7 2 0 0 2 2 2 0 Ion transport protein Sulphotransf PF09037.5 GAM19667.1 - 0.11 11.9 0.2 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Stf0 sulphotransferase ING PF12998.2 GAM19667.1 - 0.14 12.4 1.7 0.46 10.7 1.2 1.9 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding WD40 PF00400.27 GAM19668.1 - 4.8e-42 140.3 9.8 2.4e-08 33.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM19668.1 - 1.4e-08 34.6 6.1 0.032 13.9 0.0 4.2 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A DUF4073 PF13285.1 GAM19668.1 - 0.19 11.1 1.1 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) 7tm_3 PF00003.17 GAM19669.1 - 1.2e-23 83.7 28.0 1.2e-23 83.7 19.4 2.1 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Serglycin PF04360.7 GAM19670.1 - 0.018 14.7 0.8 0.034 13.8 0.5 1.5 1 0 0 1 1 1 0 Serglycin UQ_con PF00179.21 GAM19674.1 - 4.8e-28 97.3 0.0 7.6e-28 96.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.6 GAM19674.1 - 0.0057 16.1 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 GAM19674.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B GATA PF00320.22 GAM19675.1 - 5.1e-15 54.5 2.3 1.2e-14 53.3 1.6 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 GAM19675.1 - 0.027 14.4 0.4 0.059 13.3 0.3 1.5 1 0 0 1 1 1 0 zinc-finger FNIP PF05725.7 GAM19677.1 - 2.8e-82 270.4 64.2 1.1e-13 50.9 0.6 8.7 3 2 8 11 11 11 11 FNIP Repeat DUF1769 PF08588.5 GAM19677.1 - 0.00065 19.5 0.5 0.29 11.1 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM19678.1 - 9.1e-57 188.7 31.6 1.2e-10 41.1 0.1 9.6 4 4 4 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM19678.1 - 0.0086 16.0 1.2 8.4 6.4 0.1 4.1 3 1 1 4 4 4 2 Protein of unknown function (DUF1769) RF-1 PF00472.15 GAM19679.1 - 1.1e-37 128.2 1.7 2e-37 127.4 1.2 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 GAM19679.1 - 5.6e-34 116.3 1.5 1.9e-33 114.5 0.1 2.2 1 1 0 2 2 2 1 PCRF domain MIR PF02815.14 GAM19679.1 - 0.04 13.4 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 MIR domain CK1gamma_C PF12605.3 GAM19680.1 - 0.015 15.8 0.4 0.015 15.8 0.3 1.2 1 1 0 1 1 1 0 Casein kinase 1 gamma C terminal DUF4538 PF15061.1 GAM19680.1 - 0.058 12.7 3.2 0.09 12.0 2.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4538) SapA PF02199.10 GAM19681.1 - 0.016 14.9 62.0 2 8.2 0.1 11.6 11 0 0 11 11 11 0 Saposin A-type domain DUF1929 PF09118.6 GAM19681.1 - 0.075 13.1 11.5 22 5.2 0.1 5.5 1 1 4 5 5 5 0 Domain of unknown function (DUF1929) Permease PF02405.11 GAM19681.1 - 4.2 6.8 7.7 2.9 7.3 0.3 2.7 2 1 1 3 3 3 0 Permease SNAPc_SNAP43 PF09808.4 GAM19682.1 - 1.6e-26 93.1 0.1 4.3e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Pox_RNA_Pol_19 PF05320.7 GAM19682.1 - 0.59 9.8 7.8 1.5 8.5 5.4 1.8 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PAT1 PF09770.4 GAM19682.1 - 0.89 7.7 13.8 1.2 7.2 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.6 GAM19682.1 - 6.2 5.0 16.6 9.7 4.3 11.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF2053 PF09767.4 GAM19683.1 - 2.9e-33 115.1 1.8 2.9e-33 115.1 1.2 1.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) PP_kinase_C PF13090.1 GAM19684.1 - 1.6e-135 451.2 0.1 1.6e-135 451.2 0.1 1.7 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain PP_kinase PF02503.12 GAM19684.1 - 1.2e-64 217.6 3.4 2.2e-64 216.8 2.4 1.5 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.1 GAM19684.1 - 6.1e-21 74.5 0.8 6.1e-21 74.5 0.6 2.8 2 0 0 2 2 2 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.1 GAM19684.1 - 1.9e-09 37.3 0.2 0.0032 17.2 0.0 3.5 3 0 0 3 3 3 2 PLD-like domain YL1 PF05764.8 GAM19684.1 - 0.045 13.3 24.7 0.095 12.2 17.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Cellulose_synt PF03552.9 GAM19684.1 - 3.8 5.6 7.1 5.8 5.0 4.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.11 GAM19684.1 - 4.3 7.1 7.2 0.81 9.5 0.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.3 GAM19684.1 - 7.4 5.2 23.7 13 4.3 16.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ank_2 PF12796.2 GAM19685.1 - 4.8e-56 187.0 27.4 2.6e-10 40.5 0.1 8.9 2 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM19685.1 - 1.9e-38 129.6 31.7 0.00011 22.2 0.3 17.7 6 4 14 20 20 20 13 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM19685.1 - 1.8e-36 123.8 23.3 4.1e-05 23.9 0.0 12.7 5 2 6 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19685.1 - 9.1e-31 102.8 25.9 0.11 12.8 0.0 18.5 13 5 6 19 19 19 8 Ankyrin repeat Ank PF00023.25 GAM19685.1 - 5.8e-24 82.6 17.2 0.78 9.6 0.1 16.0 16 1 1 17 17 17 7 Ankyrin repeat DUF3447 PF11929.3 GAM19685.1 - 0.0011 18.7 8.2 15 5.4 0.0 6.9 6 2 1 7 7 7 1 Domain of unknown function (DUF3447) YL1 PF05764.8 GAM19686.1 - 0.035 13.7 22.1 0.039 13.5 15.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF506 PF04720.7 GAM19686.1 - 0.71 9.4 12.1 0.95 9.0 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CDC45 PF02724.9 GAM19686.1 - 0.74 7.7 17.9 0.83 7.6 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP1_N PF06424.7 GAM19686.1 - 1.1 9.5 19.0 1.5 9.1 13.2 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Sporozoite_P67 PF05642.6 GAM19686.1 - 1.1 6.9 12.0 1.3 6.7 8.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IncA PF04156.9 GAM19686.1 - 8.1 5.9 8.0 7.9 6.0 5.6 1.2 1 0 0 1 1 1 0 IncA protein VPS9 PF02204.13 GAM19687.1 - 4.5e-23 81.2 1.6 1e-22 80.1 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.20 GAM19688.1 - 2.9e-52 177.3 0.0 4.2e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19688.1 - 3.5e-35 121.3 0.0 5.9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM19688.1 - 6e-16 58.6 0.0 1.9e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 GAM19688.1 - 1.4e-07 30.7 0.0 2.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 GAM19688.1 - 0.2 9.8 13.5 0.24 9.5 9.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 GAM19689.1 - 6.7e-43 146.8 19.7 1.3e-41 142.6 0.2 2.6 1 1 1 2 2 2 2 ZIP Zinc transporter Mem_trans PF03547.13 GAM19689.1 - 0.00019 19.8 0.0 0.00029 19.2 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein DUF1510 PF07423.6 GAM19689.1 - 0.064 12.6 14.4 0.09 12.1 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3611 PF12263.3 GAM19689.1 - 0.11 11.8 0.6 0.27 10.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF913 PF06025.7 GAM19689.1 - 0.26 9.9 2.2 0.38 9.4 1.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S49_N PF08496.5 GAM19689.1 - 0.27 11.0 5.2 0.5 10.1 3.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TRAP_alpha PF03896.11 GAM19689.1 - 0.37 9.7 3.0 0.55 9.1 2.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3464 PF11947.3 GAM19689.1 - 0.52 9.7 3.9 1.5 8.2 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) TFIIF_alpha PF05793.7 GAM19689.1 - 0.93 7.7 22.3 1.2 7.3 15.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.7 GAM19689.1 - 1.9 8.3 8.0 3.1 7.6 5.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 GAM19689.1 - 8.9 6.1 12.3 13 5.5 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Actin PF00022.14 GAM19690.1 - 6.5e-89 298.0 0.0 8e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAM19690.1 - 0.033 12.7 0.0 2 6.9 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein TraH_2 PF06871.6 GAM19690.1 - 0.13 11.7 2.5 0.21 10.9 1.7 1.2 1 0 0 1 1 1 0 TraH_2 TFIIB PF00382.14 GAM19691.1 - 0.00058 19.6 0.2 0.0095 15.7 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Chorion_3 PF05387.6 GAM19691.1 - 0.043 13.2 0.1 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Chorion family 3 RRN7 PF11781.3 GAM19691.1 - 0.14 11.6 0.9 0.3 10.6 0.6 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Pkinase PF00069.20 GAM19693.1 - 2.1e-79 266.3 0.0 2.6e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19693.1 - 3.7e-40 137.6 0.0 5e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM19693.1 - 2e-05 23.7 0.1 4.7e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM19693.1 - 0.00038 19.8 0.2 0.0052 16.1 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 GAM19693.1 - 0.00068 18.6 0.0 0.003 16.5 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 GAM19693.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Josephin PF02099.12 GAM19694.1 - 1.5e-50 170.9 0.1 2.1e-50 170.4 0.1 1.2 1 0 0 1 1 1 1 Josephin UIM PF02809.15 GAM19694.1 - 0.015 14.8 8.7 0.035 13.6 1.0 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif Peptidase_C39 PF03412.10 GAM19694.1 - 0.082 12.7 0.1 3.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C39 family Ras PF00071.17 GAM19695.1 - 4.8e-66 221.1 0.1 5.7e-66 220.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19695.1 - 1.7e-19 70.4 0.0 2.8e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19695.1 - 1.4e-15 56.9 0.1 1.8e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM19695.1 - 1.8e-06 27.3 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM19695.1 - 2.1e-06 27.2 0.2 7.3e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM19695.1 - 0.0001 22.2 0.1 0.00015 21.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM19695.1 - 0.00052 19.2 0.0 0.0014 17.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 GAM19695.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAM19695.1 - 0.019 13.6 0.6 3.5 6.2 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 GAM19695.1 - 0.041 13.4 0.1 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM19695.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3963 PF13124.1 GAM19695.1 - 0.071 12.9 0.3 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) MCM PF00493.18 GAM19695.1 - 0.071 11.9 0.0 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family AAA_22 PF13401.1 GAM19695.1 - 0.074 13.2 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM19695.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) YARHG PF13308.1 GAM19696.1 - 0.00022 20.7 0.1 0.00045 19.7 0.1 1.6 1 0 0 1 1 1 1 YARHG domain DREV PF05219.7 GAM19697.1 - 1.2e-52 178.4 0.1 2.7e-44 151.0 0.0 2.2 2 0 0 2 2 2 2 DREV methyltransferase Methyltransf_11 PF08241.7 GAM19697.1 - 1.2e-11 44.9 0.0 1e-10 41.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM19697.1 - 1.6e-10 40.9 0.0 3.7e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM19697.1 - 1.6e-09 38.0 0.0 5.8e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM19697.1 - 1.6e-06 28.6 0.0 4.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM19697.1 - 2.9e-06 26.9 0.0 1.7e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM19697.1 - 0.00074 19.8 0.0 0.0038 17.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 GAM19697.1 - 0.0041 16.2 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PPR_2 PF13041.1 GAM19698.1 - 0.00027 20.8 12.1 0.0024 17.7 1.0 5.0 4 2 2 6 6 6 1 PPR repeat family PPR_3 PF13812.1 GAM19698.1 - 0.0072 16.5 2.9 0.66 10.3 0.1 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 GAM19698.1 - 0.016 15.1 3.6 1.2 9.2 0.4 4.4 4 0 0 4 4 4 0 PPR repeat ABC2_membrane PF01061.19 GAM19699.1 - 2.2e-94 314.5 67.3 8.8e-51 172.0 19.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAM19699.1 - 2.4e-39 134.7 0.0 7.3e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 GAM19699.1 - 4.3e-27 93.7 11.8 2.6e-22 78.4 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 GAM19699.1 - 9.3e-15 54.4 52.1 5.4e-12 45.4 9.5 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 GAM19699.1 - 1.7e-10 40.8 0.2 4.7e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 GAM19699.1 - 2.6e-06 27.6 0.8 0.022 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAM19699.1 - 2.7e-06 26.6 0.0 0.00051 19.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM19699.1 - 2.8e-06 26.7 0.3 0.0019 17.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM19699.1 - 4.5e-06 26.1 0.0 0.00021 20.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM19699.1 - 0.00015 21.8 0.2 0.074 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM19699.1 - 0.0014 19.4 0.0 0.31 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM19699.1 - 0.0018 18.2 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 GAM19699.1 - 0.0026 18.0 0.7 0.36 11.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 GAM19699.1 - 0.014 14.8 0.7 0.28 10.6 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 GAM19699.1 - 0.018 14.9 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.1 GAM19699.1 - 0.026 13.6 4.6 0.52 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.1 GAM19699.1 - 0.034 14.1 1.1 0.13 12.1 0.5 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM19699.1 - 0.045 13.3 0.4 0.64 9.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 GAM19699.1 - 0.05 13.5 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 GAM19699.1 - 0.09 12.6 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM19699.1 - 0.12 12.1 0.0 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 GAM19699.1 - 0.12 12.6 0.2 4.1 7.6 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 GAM19699.1 - 0.13 11.6 0.8 1.3 8.5 0.3 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 GAM19699.1 - 0.16 11.3 0.0 7 6.0 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 GAM19699.1 - 0.19 11.3 0.5 3.2 7.3 0.3 2.3 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 GAM19699.1 - 0.19 11.2 0.1 4.2 6.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain Vps55 PF04133.9 GAM19700.1 - 1.4e-32 111.9 6.2 1.5e-32 111.8 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4077 PF13295.1 GAM19700.1 - 0.92 9.2 5.3 0.21 11.2 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4077) mRNA_cap_enzyme PF01331.14 GAM19701.1 - 2.1e-36 125.4 0.2 5.7e-36 124.0 0.1 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_triPase PF02940.10 GAM19701.1 - 1.1e-17 64.4 2.0 1.9e-15 57.2 0.5 2.6 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain mRNA_cap_C PF03919.10 GAM19701.1 - 2.3e-10 40.7 0.5 7.5e-10 39.0 0.3 1.9 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 GAM19701.1 - 5.6e-08 32.4 0.1 1.4e-05 24.5 0.0 2.9 2 1 0 2 2 2 1 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.4 GAM19701.1 - 4.2e-05 22.4 1.6 0.0031 16.3 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase PTE PF02126.13 GAM19702.1 - 5.1e-83 278.6 0.6 6.1e-83 278.3 0.4 1.1 1 0 0 1 1 1 1 Phosphotriesterase family Rhomboid PF01694.17 GAM19703.1 - 1.3e-11 44.7 18.5 2.3e-10 40.6 12.8 2.4 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.10 GAM19703.1 - 0.17 11.4 11.5 2.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Der1-like family ABC_tran PF00005.22 GAM19704.1 - 5e-41 140.2 0.1 4.7e-20 72.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 GAM19704.1 - 1.7e-25 90.5 3.2 1.7e-11 44.6 0.1 4.2 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 GAM19704.1 - 1.3e-12 47.4 0.7 1.3e-07 31.0 0.0 3.8 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM19704.1 - 2.5e-09 36.5 0.0 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 GAM19704.1 - 2.6e-09 36.6 0.0 0.02 13.9 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 GAM19704.1 - 2.2e-08 34.3 2.7 0.00015 21.9 0.2 3.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM19704.1 - 5.4e-08 33.0 9.0 0.00029 20.8 0.2 3.3 1 1 2 3 3 3 2 AAA ATPase domain NACHT PF05729.7 GAM19704.1 - 1.1e-07 31.6 0.0 0.0066 16.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 GAM19704.1 - 6.6e-07 28.6 0.1 0.0075 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 GAM19704.1 - 7.6e-07 29.6 0.0 0.0061 17.0 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein ATP-synt_ab PF00006.20 GAM19704.1 - 7.8e-07 28.8 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 GAM19704.1 - 1e-06 29.2 4.9 0.0038 17.5 0.1 3.1 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 GAM19704.1 - 2.7e-06 27.3 0.0 0.0056 16.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM19704.1 - 3.4e-06 26.9 0.6 0.0016 18.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAM19704.1 - 5.2e-06 26.0 0.4 0.056 12.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 GAM19704.1 - 7.9e-06 25.9 1.6 0.065 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 GAM19704.1 - 1.6e-05 24.5 0.0 0.26 10.9 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 GAM19704.1 - 1.7e-05 25.6 0.4 0.3 11.9 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM19704.1 - 1.9e-05 24.3 0.4 0.018 14.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM19704.1 - 2.4e-05 24.5 0.1 0.15 12.2 0.0 3.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 GAM19704.1 - 3.9e-05 23.1 0.1 0.095 12.1 0.0 2.7 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 GAM19704.1 - 4e-05 23.2 4.8 0.036 13.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 GAM19704.1 - 4.6e-05 23.2 0.1 0.061 13.2 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.14 GAM19704.1 - 5.5e-05 22.6 0.2 0.15 11.4 0.0 2.9 3 0 0 3 3 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAM19704.1 - 0.0001 21.8 0.1 0.23 10.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family ArgK PF03308.11 GAM19704.1 - 0.00038 19.3 0.0 0.42 9.3 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_19 PF13245.1 GAM19704.1 - 0.00039 20.1 0.9 0.035 13.8 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 GAM19704.1 - 0.00039 20.0 0.4 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran_2 PF12848.2 GAM19704.1 - 0.00063 19.5 3.0 0.0015 18.3 2.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 GAM19704.1 - 0.00086 19.6 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 GAM19704.1 - 0.002 17.8 0.2 0.53 9.9 0.0 2.8 2 0 0 2 2 2 1 NTPase AAA_13 PF13166.1 GAM19704.1 - 0.0031 16.0 5.4 0.16 10.3 0.0 3.3 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.17 GAM19704.1 - 0.0031 16.3 0.0 0.53 9.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 GAM19704.1 - 0.0032 17.6 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 GAM19704.1 - 0.0033 16.3 0.0 0.75 8.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAM19704.1 - 0.0049 16.7 0.0 8.6 6.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 GAM19704.1 - 0.012 15.2 0.2 2.3 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM19704.1 - 0.014 14.8 0.4 1.2 8.5 0.0 2.8 2 1 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 GAM19704.1 - 0.015 14.0 0.1 0.3 9.7 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit SRP54 PF00448.17 GAM19704.1 - 0.015 14.7 0.1 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 GAM19704.1 - 0.016 14.2 1.1 1.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin Septin PF00735.13 GAM19704.1 - 0.022 13.7 0.1 3.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 GAM19704.1 - 0.029 14.0 2.6 0.62 9.7 0.0 3.0 4 0 0 4 4 3 0 Archaeal ATPase Thymidylate_kin PF02223.12 GAM19704.1 - 0.033 13.5 0.2 1.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.16 GAM19704.1 - 0.033 13.3 0.0 7.5 5.6 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 GAM19704.1 - 0.036 13.0 0.0 0.48 9.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain MCM PF00493.18 GAM19704.1 - 0.04 12.7 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family Dynamin_N PF00350.18 GAM19704.1 - 0.044 13.5 2.0 0.62 9.8 0.1 2.8 3 0 0 3 3 2 0 Dynamin family Bac_DnaA PF00308.13 GAM19704.1 - 0.052 13.1 0.1 0.13 11.8 0.0 1.7 2 0 0 2 2 1 0 Bacterial dnaA protein DUF2813 PF11398.3 GAM19704.1 - 0.071 12.1 0.4 2 7.3 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) FeoB_N PF02421.13 GAM19704.1 - 0.078 12.2 0.1 3.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Pox_A32 PF04665.7 GAM19704.1 - 0.08 12.2 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein GTP_EFTU PF00009.22 GAM19704.1 - 0.084 12.3 0.1 6 6.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 GAM19704.1 - 1 9.1 3.4 3 7.6 0.0 2.8 3 1 0 3 3 2 0 Domain of unknown function DUF87 DUF3584 PF12128.3 GAM19704.1 - 2.7 5.2 15.8 0.2 8.9 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Peptidase_M8 PF01457.11 GAM19705.1 - 1.1e-58 198.8 0.4 1.4e-58 198.5 0.3 1.1 1 0 0 1 1 1 1 Leishmanolysin Kelch_6 PF13964.1 GAM19706.1 - 5.4e-08 32.6 4.7 0.019 15.1 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM19706.1 - 3.3e-07 29.9 5.3 0.082 12.6 0.1 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.19 GAM19706.1 - 7.2e-05 22.5 1.8 0.00017 21.4 1.2 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.1 GAM19706.1 - 0.00015 21.6 4.6 0.012 15.5 0.2 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM19706.1 - 0.0002 21.0 2.8 0.025 14.3 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 GAM19706.1 - 0.096 12.2 6.3 19 4.8 0.3 4.4 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 GAM19706.1 - 0.13 12.4 2.4 28 5.0 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Peptidase_M8 PF01457.11 GAM19707.1 - 9.4e-69 232.1 7.0 1.4e-68 231.5 4.9 1.2 1 0 0 1 1 1 1 Leishmanolysin HisKA_3 PF07730.8 GAM19708.1 - 0.0053 17.0 0.1 0.019 15.2 0.0 1.9 2 1 0 2 2 2 1 Histidine kinase THP2 PF09432.5 GAM19708.1 - 0.22 11.4 3.0 0.34 10.7 1.7 1.7 1 1 1 2 2 2 0 Tho complex subunit THP2 DUF4515 PF14988.1 GAM19708.1 - 1.4 8.5 8.5 4.4 6.9 1.3 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) Syntaxin_2 PF14523.1 GAM19708.1 - 9.6 6.3 10.2 2.7 8.0 0.2 2.4 1 1 1 2 2 2 0 Syntaxin-like protein Thioredoxin PF00085.15 GAM19709.1 - 3.1e-27 94.3 0.0 3.4e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 GAM19709.1 - 1.1e-08 35.1 1.5 1e-07 31.9 0.3 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAM19709.1 - 6.3e-06 26.3 0.3 0.00047 20.3 0.2 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM19709.1 - 0.0005 20.1 0.1 0.044 13.8 0.0 3.0 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 GAM19709.1 - 0.066 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin Peptidase_C1 PF00112.18 GAM19710.1 - 2.8e-66 223.5 6.6 4e-66 223.0 4.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM19710.1 - 5.9e-16 58.4 1.8 1.1e-15 57.6 1.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM19710.1 - 2.3e-08 33.0 0.9 0.0011 17.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PB1 PF00564.19 GAM19711.1 - 0.0035 16.9 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF3877 PF12993.2 GAM19711.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) RIC3 PF15361.1 GAM19711.1 - 0.057 13.6 1.8 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Pex16 PF08610.5 GAM19713.1 - 3.1e-46 157.9 5.0 5.9e-45 153.7 3.5 2.0 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SSXT PF05030.7 GAM19714.1 - 1.4e-13 50.2 4.0 5.2e-13 48.3 2.8 2.0 1 0 0 1 1 1 1 SSXT protein (N-terminal region) Myb_DNA-binding PF00249.26 GAM19715.1 - 8.2e-10 38.5 0.2 1.6e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain CH PF00307.26 GAM19716.1 - 5.4e-14 52.1 0.0 1.4e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM19716.1 - 0.00019 20.9 0.0 0.00046 19.7 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Ank_2 PF12796.2 GAM19717.1 - 2.1e-36 124.1 14.6 8.3e-11 42.0 0.4 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM19717.1 - 5.6e-23 80.8 8.5 0.00013 22.4 0.1 7.2 5 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19717.1 - 7.9e-22 75.1 11.3 0.0066 16.5 0.0 9.8 4 1 6 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 GAM19717.1 - 1.7e-21 75.7 6.6 0.023 14.9 0.0 9.7 3 2 7 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM19717.1 - 1e-15 56.6 12.9 1.9 8.4 0.0 9.1 7 2 2 9 9 9 7 Ankyrin repeat DUF3447 PF11929.3 GAM19717.1 - 0.035 13.8 8.6 2.1 8.1 0.1 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3447) TIG PF01833.19 GAM19718.1 - 2.3e-59 197.3 109.4 1.1e-12 47.8 4.5 15.0 14 1 0 14 14 14 12 IPT/TIG domain DNase_II PF03265.10 GAM19718.1 - 3.1e-18 65.8 0.6 1.5e-10 40.6 0.3 2.3 2 0 0 2 2 2 2 Deoxyribonuclease II Qn_am_d_aIII PF09099.5 GAM19718.1 - 0.0015 18.8 0.1 12 6.3 0.0 3.9 3 0 0 3 3 3 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III CAP PF00188.21 GAM19720.1 - 1.1e-18 67.9 1.0 2.2e-18 66.9 0.7 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Herpes_BLLF1 PF05109.8 GAM19720.1 - 0.58 8.0 95.5 0.68 7.8 66.2 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) FAM196 PF15265.1 GAM19720.1 - 1.2 8.2 34.4 1.6 7.8 23.8 1.2 1 0 0 1 1 1 0 FAM196 family Kelch_6 PF13964.1 GAM19721.1 - 5.3e-08 32.6 7.1 0.00028 20.8 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM19721.1 - 1.4e-07 31.1 0.4 1.4e-06 27.9 0.0 2.9 4 0 0 4 4 4 1 Galactose oxidase, central domain zf-B_box PF00643.19 GAM19721.1 - 2e-05 24.3 8.3 2e-05 24.3 5.8 2.3 2 0 0 2 2 2 1 B-box zinc finger Kelch_3 PF13415.1 GAM19721.1 - 0.0006 19.9 1.5 0.016 15.3 0.0 3.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM19721.1 - 0.00082 18.8 5.6 0.0045 16.4 0.0 4.1 4 0 0 4 4 4 1 Kelch motif zf-C3HC4_2 PF13923.1 GAM19721.1 - 0.067 13.2 6.4 3.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 GAM19721.1 - 1.5 8.7 7.5 4 7.3 3.1 2.6 2 0 0 2 2 2 0 IBR domain PDEase_I_N PF08499.7 GAM19722.1 - 0.3 11.0 3.1 9.4 6.2 0.0 2.4 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal WD40 PF00400.27 GAM19725.1 - 1.9e-39 132.1 26.4 1.1e-08 34.6 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM19725.1 - 3e-05 22.3 7.5 0.017 13.3 0.9 4.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 GAM19725.1 - 0.0049 15.8 0.4 0.23 10.3 0.0 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF1513) TetM_leader PF08076.6 GAM19725.1 - 2.1 7.9 6.3 12 5.5 0.5 3.1 3 0 0 3 3 3 0 Tetracycline resistance determinant leader peptide zf-RING_2 PF13639.1 GAM19726.1 - 2e-13 49.9 6.9 2e-13 49.9 4.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_3 PF14369.1 GAM19726.1 - 6.6e-09 35.6 4.8 6.6e-09 35.6 3.4 2.2 2 0 0 2 2 2 1 zinc-finger zf-rbx1 PF12678.2 GAM19726.1 - 8.5e-07 29.0 6.3 8.5e-07 29.0 4.4 2.7 2 2 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAM19726.1 - 1.5e-06 27.7 10.2 1.3e-05 24.7 2.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM19726.1 - 6.8e-06 25.7 4.0 6.8e-06 25.7 2.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM19726.1 - 4.2e-05 23.4 7.0 4.2e-05 23.4 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 GAM19726.1 - 5.1e-05 22.9 8.3 0.0024 17.5 0.5 2.7 2 1 1 3 3 3 2 Hydrogenase expression/synthesis hypA family zf-C3HC4 PF00097.20 GAM19726.1 - 6.7e-05 22.4 6.7 6.7e-05 22.4 4.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NinG PF05766.7 GAM19726.1 - 0.00011 22.0 0.4 0.00011 22.0 0.3 2.7 2 1 0 2 2 2 1 Bacteriophage Lambda NinG protein FCP1_C PF09309.5 GAM19726.1 - 0.0011 18.3 11.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 1 FCP1, C-terminal zf-Apc11 PF12861.2 GAM19726.1 - 0.0017 18.1 2.4 0.0017 18.1 1.7 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 GAM19726.1 - 0.0022 17.6 12.8 0.015 15.0 0.9 3.3 2 1 1 3 3 3 1 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.7 GAM19726.1 - 0.017 14.8 2.7 0.017 14.8 1.8 2.9 3 0 0 3 3 3 0 PhnA Zinc-Ribbon FYDLN_acid PF09538.5 GAM19726.1 - 0.018 15.6 1.0 0.018 15.6 0.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DZR PF12773.2 GAM19726.1 - 0.072 12.9 8.6 0.28 11.0 0.2 3.0 2 1 1 3 3 3 0 Double zinc ribbon BRF1 PF07741.8 GAM19726.1 - 0.19 11.9 5.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rad50_zn_hook PF04423.9 GAM19726.1 - 0.29 10.6 7.0 0.31 10.5 0.0 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-FCS PF06467.9 GAM19726.1 - 0.39 10.3 4.0 13 5.5 0.0 3.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-RING_4 PF14570.1 GAM19726.1 - 1.5 8.5 12.5 1.3 8.6 0.5 3.0 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Suf PF05843.9 GAM19726.1 - 1.6 8.3 14.9 0.64 9.7 3.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) A2L_zn_ribbon PF08792.5 GAM19726.1 - 3.6 7.1 10.4 0.079 12.4 0.4 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain Ctr PF04145.10 GAM19726.1 - 5.4 7.0 7.1 4.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Ctr copper transporter family RNA_POL_M_15KD PF02150.11 GAM19726.1 - 6.1 6.6 8.6 9.2 6.0 0.1 3.4 3 1 1 4 4 4 0 RNA polymerases M/15 Kd subunit Peptidase_S10 PF00450.17 GAM19727.1 - 8.4e-109 364.4 3.5 1e-108 364.1 2.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Herpes_UL45 PF05473.7 GAM19727.1 - 0.18 11.2 0.1 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 UL45 protein UQ_con PF00179.21 GAM19728.1 - 4.6e-37 126.5 0.1 6.2e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM19728.1 - 0.097 12.5 0.5 0.22 11.4 0.3 1.8 1 1 0 1 1 1 0 RWD domain TPR_1 PF00515.23 GAM19729.1 - 0.0011 18.4 0.1 0.0027 17.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM19729.1 - 0.0015 18.1 0.1 0.0032 17.0 0.1 1.6 1 0 0 1 1 1 1 TPR repeat Apc3 PF12895.2 GAM19729.1 - 0.0022 18.0 0.4 0.0056 16.8 0.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM19729.1 - 0.0083 15.9 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM19729.1 - 0.019 14.8 0.3 0.094 12.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM19729.1 - 0.019 14.8 0.4 0.049 13.5 0.3 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 GAM19729.1 - 0.021 14.7 0.2 0.085 12.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM19729.1 - 0.027 14.2 0.8 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM19729.1 - 0.046 14.4 1.2 0.081 13.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Baculo_IE-1 PF05290.6 GAM19729.1 - 0.091 12.4 0.1 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) TPR_14 PF13428.1 GAM19729.1 - 0.1 13.2 0.7 0.27 11.9 0.0 2.1 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM19729.1 - 0.11 12.3 0.3 0.36 10.7 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat Ima1_N PF09779.4 GAM19730.1 - 2.9e-18 66.6 14.9 2.9e-18 66.6 10.3 2.0 2 0 0 2 2 2 1 Ima1 N-terminal domain DUF2719 PF10891.3 GAM19730.1 - 0.011 15.3 0.4 0.047 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2719) CAP PF00188.21 GAM19731.1 - 4.6e-13 49.7 0.0 5.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family UBA PF00627.26 GAM19732.1 - 5.1e-18 64.3 2.8 8.3e-11 41.3 0.6 2.4 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 GAM19732.1 - 5.9e-17 60.8 1.2 1.2e-16 59.9 0.8 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 GAM19732.1 - 2e-14 52.7 0.3 3.6e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.5 GAM19732.1 - 2.1e-05 23.9 0.0 0.092 12.3 0.0 2.6 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD PF11976.3 GAM19732.1 - 4.8e-05 22.9 0.2 0.00014 21.4 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAM19732.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF605 PF04652.11 GAM19732.1 - 0.087 12.2 4.9 0.12 11.7 3.4 1.2 1 0 0 1 1 1 0 Vta1 like MCM_N PF14551.1 GAM19732.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 MCM N-terminal domain LolA PF03548.10 GAM19732.1 - 0.2 11.2 1.4 0.53 9.8 0.0 2.3 3 0 0 3 3 3 0 Outer membrane lipoprotein carrier protein LolA RuvA_C PF07499.8 GAM19732.1 - 0.21 11.7 0.8 4.2 7.6 0.1 2.4 2 0 0 2 2 2 0 RuvA, C-terminal domain DUF2457 PF10446.4 GAM19732.1 - 0.52 8.9 8.9 0.77 8.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Thioredoxin PF00085.15 GAM19733.1 - 7.7e-06 25.5 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin FERM_M PF00373.13 GAM19734.1 - 4.1e-21 75.4 1.3 6.6e-21 74.7 0.2 1.9 2 0 0 2 2 2 1 FERM central domain LRR_6 PF13516.1 GAM19734.1 - 7.5e-09 34.7 41.5 0.082 13.0 0.3 13.4 13 1 1 14 14 14 3 Leucine Rich repeat FERM_N PF09379.5 GAM19734.1 - 2.7e-07 30.5 0.1 8.5e-07 28.9 0.1 1.9 1 0 0 1 1 1 1 FERM N-terminal domain LRR_4 PF12799.2 GAM19734.1 - 1.3e-05 24.6 33.5 0.057 13.0 1.8 8.9 7 1 2 9 9 9 4 Leucine Rich repeats (2 copies) FBA_2 PF07735.12 GAM19734.1 - 0.002 17.9 1.5 0.014 15.2 1.1 2.6 1 0 0 1 1 1 1 F-box associated LRR_1 PF00560.28 GAM19734.1 - 0.38 10.9 27.9 18 5.8 0.4 10.6 9 3 1 10 10 10 0 Leucine Rich Repeat tRNA_Me_trans PF03054.11 GAM19735.1 - 2.2e-106 355.4 0.0 2.7e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 GAM19735.1 - 4.4e-06 26.3 0.0 6.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 GAM19735.1 - 9.6e-06 24.6 0.0 3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.9 GAM19735.1 - 1e-05 25.0 0.0 3.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.15 GAM19735.1 - 0.0019 17.7 0.1 0.024 14.1 0.0 2.3 1 1 0 1 1 1 1 PP-loop family QueC PF06508.8 GAM19735.1 - 0.0045 16.2 0.0 0.017 14.4 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Transket_pyr PF02779.19 GAM19736.1 - 9.7e-64 214.1 0.0 2e-63 213.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 GAM19736.1 - 1.5e-60 204.4 0.0 2.2e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Coiled PF05710.7 GAM19737.1 - 0.022 15.2 12.6 0.027 14.9 8.8 1.1 1 0 0 1 1 1 0 Coiled coil FNIP PF05725.7 GAM19739.1 - 1.1e-94 310.2 43.9 1.2e-13 50.7 0.5 12.8 6 3 5 13 13 13 11 FNIP Repeat DUF1769 PF08588.5 GAM19739.1 - 0.015 15.1 8.9 13 5.7 0.0 6.9 3 2 5 8 8 8 0 Protein of unknown function (DUF1769) Complex1_LYR PF05347.10 GAM19740.1 - 1.4e-08 34.3 2.5 2.5e-08 33.6 0.5 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM19740.1 - 1.4e-06 28.3 1.8 1.7e-06 28.1 0.3 1.9 2 1 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAM19740.1 - 8.1e-06 26.2 0.2 1.3e-05 25.6 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Pyr_redox PF00070.22 GAM19741.1 - 3e-19 69.1 2.8 3.4e-12 46.6 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM19741.1 - 6.6e-12 45.7 0.0 4.6e-11 42.9 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM19741.1 - 2e-10 40.1 0.1 0.049 12.5 0.3 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM19741.1 - 7e-09 35.5 0.1 0.0053 16.7 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM19741.1 - 3.8e-07 30.3 0.2 0.00063 19.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM19741.1 - 1.1e-06 27.8 0.3 0.027 13.4 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 GAM19741.1 - 4.2e-06 25.6 0.2 0.0086 14.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DUF1188 PF06690.6 GAM19741.1 - 1.8e-05 24.0 0.2 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 GAM19741.1 - 1.8e-05 24.6 0.2 0.33 10.9 0.0 2.8 2 0 0 2 2 2 2 TrkA-N domain Lycopene_cycl PF05834.7 GAM19741.1 - 4.7e-05 22.4 0.0 0.063 12.1 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.1 GAM19741.1 - 6.9e-05 23.0 0.8 0.12 12.6 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding HI0933_like PF03486.9 GAM19741.1 - 9.3e-05 21.0 0.1 0.038 12.4 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 GAM19741.1 - 0.00013 21.7 4.4 1.2 8.8 0.0 3.8 3 1 1 4 4 4 2 FAD-NAD(P)-binding 3HCDH_N PF02737.13 GAM19741.1 - 0.00031 20.4 0.1 0.46 10.1 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM19741.1 - 0.0011 18.1 0.0 0.27 10.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Saccharop_dh PF03435.13 GAM19741.1 - 0.003 16.5 0.4 1 8.2 0.1 2.4 2 0 0 2 2 2 2 Saccharopine dehydrogenase ApbA PF02558.11 GAM19741.1 - 0.0044 16.4 0.1 0.52 9.7 0.1 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DUF2498 PF10692.4 GAM19741.1 - 0.0074 15.8 0.2 4.2 7.0 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2498) GIDA PF01134.17 GAM19741.1 - 0.012 14.5 0.0 2.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 GAM19741.1 - 0.013 15.2 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 GAM19741.1 - 0.018 14.4 0.7 3.7 6.8 0.1 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 GAM19741.1 - 0.021 14.9 0.1 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 GAM19741.1 - 0.039 14.2 0.6 1.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 GAM19741.1 - 0.23 11.2 1.6 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain DUF663 PF04950.7 GAM19742.1 - 6.7e-84 281.3 0.0 6.7e-84 281.3 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAM19742.1 - 3.7e-18 64.8 0.0 9.2e-18 63.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SPATIAL PF15256.1 GAM19743.1 - 0.076 13.0 5.0 0.12 12.4 3.5 1.2 1 0 0 1 1 1 0 SPATIAL Rifin_STEVOR PF02009.11 GAM19743.1 - 1.2 8.7 3.2 2.1 7.9 2.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family Chondroitinas_B PF14592.1 GAM19744.1 - 0.0045 15.8 0.1 0.0045 15.8 0.1 1.0 1 0 0 1 1 1 1 Chondroitinase B Thioredoxin PF00085.15 GAM19745.1 - 1.8e-16 59.6 0.0 2e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 GAM19745.1 - 0.00053 19.6 0.0 0.00061 19.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 GAM19745.1 - 0.00086 18.8 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAM19745.1 - 0.0083 16.2 0.1 0.022 14.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 GAM19745.1 - 0.028 13.9 0.2 0.048 13.2 0.1 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 GAM19745.1 - 0.035 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM19745.1 - 0.12 12.6 0.8 0.99 9.6 0.6 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain His_Phos_2 PF00328.17 GAM19746.1 - 2.8e-33 115.6 0.0 4.7e-33 114.9 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TIG PF01833.19 GAM19747.1 - 2.8e-11 43.2 35.7 2.1e-07 30.8 3.5 5.2 4 1 1 5 5 5 3 IPT/TIG domain Lectin_C PF00059.16 GAM19747.1 - 9.3e-05 23.0 1.3 0.00025 21.6 0.3 2.3 3 0 0 3 3 3 1 Lectin C-type domain EGF_2 PF07974.8 GAM19747.1 - 0.069 13.3 5.9 0.15 12.2 4.1 1.6 1 0 0 1 1 1 0 EGF-like domain Profilin PF00235.14 GAM19749.1 - 2.7e-06 27.4 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Profilin ABC2_membrane PF01061.19 GAM19751.1 - 7.6e-38 129.7 25.1 1.3e-37 129.0 17.4 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM19751.1 - 2e-29 102.6 0.0 4.3e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM19751.1 - 1.7e-10 41.3 1.5 2e-05 24.6 0.0 3.1 3 1 0 4 4 3 2 AAA domain AAA_25 PF13481.1 GAM19751.1 - 2.9e-05 23.5 0.2 0.00032 20.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM19751.1 - 0.00042 19.7 0.0 0.0014 18.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM19751.1 - 0.00076 19.5 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM19751.1 - 0.00079 19.5 0.1 0.0062 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM19751.1 - 0.0012 18.0 0.1 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 GAM19751.1 - 0.0016 17.7 0.1 0.25 10.5 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 GAM19751.1 - 0.0059 15.5 0.1 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAM19751.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 GAM19751.1 - 0.015 16.0 0.0 0.035 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM19751.1 - 0.016 15.5 0.5 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 GAM19751.1 - 0.019 14.7 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PDR_CDR PF06422.7 GAM19751.1 - 0.029 14.0 0.2 0.029 14.0 0.1 2.0 2 0 0 2 2 1 0 CDR ABC transporter IstB_IS21 PF01695.12 GAM19751.1 - 0.032 13.6 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SbcCD_C PF13558.1 GAM19751.1 - 0.04 13.8 0.1 0.23 11.4 0.0 2.3 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 GAM19751.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAM19751.1 - 0.045 13.3 0.4 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAM19751.1 - 0.046 13.4 0.6 9.6 5.8 0.0 2.7 3 0 0 3 3 3 0 NTPase MobB PF03205.9 GAM19751.1 - 0.073 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 GAM19751.1 - 0.089 13.1 4.9 0.11 12.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM19751.1 - 0.092 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 GAM19751.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 GAM19751.1 - 2.5 7.0 38.1 18 4.2 26.4 2.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Proteasome PF00227.21 GAM19752.1 - 3e-50 170.1 0.0 3.6e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM19752.1 - 5.9e-11 41.4 0.1 9.8e-11 40.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Homeobox PF00046.24 GAM19752.1 - 0.0093 15.5 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Homeobox domain RNase_PH PF01138.16 GAM19753.1 - 4.1e-20 72.4 0.5 8.6e-20 71.3 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAM19753.1 - 5.4e-08 32.6 0.2 2.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Copine PF07002.11 GAM19754.1 - 1.2e-45 154.7 0.0 2.3e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 Copine C2 PF00168.25 GAM19754.1 - 1e-23 82.9 0.0 6.4e-11 41.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 GAM19754.1 - 9.3e-10 38.6 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus 7tm_3 PF00003.17 GAM19755.1 - 1.2e-27 96.8 27.5 1.9e-27 96.1 19.0 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Beta_helix PF13229.1 GAM19755.1 - 0.047 13.4 40.5 3.7 7.2 11.3 4.0 1 1 1 2 2 2 0 Right handed beta helix region Chlam_PMP PF02415.12 GAM19755.1 - 1.8 8.9 0.0 1.8 8.9 0.0 7.1 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TRP PF06011.7 GAM19756.1 - 2.3e-07 29.7 38.8 1.1e-05 24.2 26.9 3.2 1 1 1 2 2 2 1 Transient receptor potential (TRP) ion channel EGF_2 PF07974.8 GAM19756.1 - 0.00022 21.2 10.8 0.00022 21.2 7.5 4.1 5 0 0 5 5 5 3 EGF-like domain PQQ_3 PF13570.1 GAM19756.1 - 7.7 6.9 6.0 2.2 8.6 0.2 3.1 3 1 1 4 4 4 0 PQQ-like domain ABC_tran PF00005.22 GAM19757.1 - 1.1e-26 93.7 0.0 1.9e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAM19757.1 - 3e-25 89.0 26.9 4.4e-25 88.4 18.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM19757.1 - 4.7e-13 49.7 2.1 4.9e-09 36.5 0.1 3.8 2 1 0 2 2 2 2 AAA domain ABC2_membrane PF01061.19 GAM19757.1 - 4.4e-05 22.7 18.8 4.4e-05 22.7 13.1 2.4 2 0 0 2 2 2 1 ABC-2 type transporter SMC_N PF02463.14 GAM19757.1 - 0.0013 18.0 0.2 0.093 11.9 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM19757.1 - 0.0021 17.5 0.5 0.0045 16.4 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM19757.1 - 0.18 12.1 2.3 0.2 11.9 0.2 2.1 2 0 0 2 2 2 0 AAA domain Membrane_bind PF14564.1 GAM19759.1 - 2e-31 108.4 0.0 3.4e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.5 GAM19759.1 - 7e-21 73.7 0.1 9.6e-21 73.3 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.5 GAM19760.1 - 2.3e-14 52.8 0.1 2.9e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.14 GAM19760.1 - 0.016 15.0 0.1 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin Pkinase PF00069.20 GAM19761.1 - 1.6e-71 240.4 0.0 3.8e-71 239.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19761.1 - 5.7e-51 173.0 0.0 1.1e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19761.1 - 2.2e-05 23.5 0.0 4.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Arm PF00514.18 GAM19761.1 - 0.00022 20.8 0.9 3.6 7.5 0.1 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Kdo PF06293.9 GAM19761.1 - 0.0045 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.14 GAM19761.1 - 0.0086 16.4 0.2 0.024 15.0 0.1 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2132 PF09905.4 GAM19761.1 - 0.051 13.5 0.4 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2132) Sas10_Utp3 PF04000.10 GAM19762.1 - 1e-19 70.4 0.8 1e-19 70.4 0.6 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.5 GAM19762.1 - 1.5e-18 66.7 9.1 1.5e-18 66.7 6.3 2.8 2 0 0 2 2 2 1 Sas10 C-terminal domain NAF PF03822.9 GAM19762.1 - 0.002 17.7 0.2 0.012 15.3 0.1 2.3 1 0 0 1 1 1 1 NAF domain GYF PF02213.11 GAM19763.1 - 8.9e-07 28.4 0.2 3.3e-06 26.5 0.1 2.1 1 0 0 1 1 1 1 GYF domain adh_short PF00106.20 GAM19764.1 - 1.3e-26 93.5 0.0 2e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM19764.1 - 2.5e-13 50.3 0.0 3.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM19764.1 - 1.7e-09 37.5 0.1 4.3e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM19764.1 - 1.6e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM19764.1 - 0.0023 16.9 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 GAM19764.1 - 0.0036 16.5 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 GAM19764.1 - 0.0076 15.7 0.1 0.011 15.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 GAM19764.1 - 0.03 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3320 PF11784.3 GAM19764.1 - 0.05 13.1 0.3 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3320) SET PF00856.23 GAM19765.1 - 3.1e-26 92.6 0.5 3.1e-26 92.6 0.3 3.4 2 2 0 2 2 2 1 SET domain RRM_6 PF14259.1 GAM19765.1 - 1.5e-10 40.8 0.0 3.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM19765.1 - 1.8e-08 33.9 0.0 4.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19765.1 - 0.00034 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM19765.1 - 0.024 14.3 0.0 0.11 12.3 0.0 2.1 1 0 0 1 1 1 0 Limkain b1 SMK-1 PF04802.10 GAM19766.1 - 1.8e-66 223.4 11.8 1.8e-66 223.4 8.2 2.2 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 CAF-1_p150 PF11600.3 GAM19766.1 - 1.9 7.7 39.0 0.037 13.4 21.6 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Daxx PF03344.10 GAM19766.1 - 2.9 6.2 59.1 4.1 5.7 40.2 1.7 1 1 1 2 2 2 0 Daxx Family CAP PF00188.21 GAM19767.1 - 1.1e-19 71.1 0.3 1.4e-19 70.7 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EMP70 PF02990.11 GAM19769.1 - 4.5e-70 236.5 9.9 6.5e-48 163.4 0.0 2.2 1 1 1 2 2 2 2 Endomembrane protein 70 EMP70 PF02990.11 GAM19770.1 - 2.9e-77 260.2 14.3 6.5e-77 259.1 9.6 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 Proteasome PF00227.21 GAM19772.1 - 1.1e-44 152.0 0.0 1.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3904 PF13044.1 GAM19773.1 - 0.11 10.8 0.0 0.12 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3904) WD40 PF00400.27 GAM19774.1 - 0.00023 20.8 5.0 2.3 8.2 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat LpxC PF03331.8 GAM19775.1 - 0.038 12.9 0.1 6 5.7 0.0 2.2 2 0 0 2 2 2 0 UDP-3-O-acyl N-acetylglycosamine deacetylase Pkinase PF00069.20 GAM19777.1 - 8.4e-73 244.7 0.0 1.2e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19777.1 - 1.4e-33 116.0 0.0 2.2e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19777.1 - 3.1e-07 29.6 0.0 3e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YukC PF10140.4 GAM19777.1 - 0.0041 15.7 0.1 0.0065 15.0 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 GAM19777.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM19777.1 - 0.3 10.7 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family BRCA-2_OB1 PF09103.5 GAM19778.1 - 1.2e-36 124.9 0.0 2.5e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 GAM19778.1 - 2e-13 50.3 0.1 2.5e-12 46.7 0.0 2.5 1 1 0 2 2 2 1 BRCA2, helical VWA PF00092.23 GAM19779.1 - 5.9e-06 26.1 0.4 1.1e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.13 GAM19779.1 - 2e-05 23.6 0.0 5.7e-05 22.1 0.0 1.7 1 1 1 2 2 2 1 Integrin, beta chain Integrin_b_cyt PF08725.6 GAM19779.1 - 0.034 13.5 0.4 0.87 9.0 0.0 2.5 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Laminin_EGF PF00053.19 GAM19779.1 - 4.1 7.4 20.3 0.64 10.0 2.6 2.4 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) Kelch_6 PF13964.1 GAM19781.1 - 6e-09 35.7 9.1 0.00048 20.1 0.1 4.7 2 1 2 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM19781.1 - 4.6e-05 23.4 1.7 1.4 9.1 0.0 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM19781.1 - 0.00051 19.7 10.0 0.037 13.7 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM19781.1 - 0.00091 18.7 18.4 0.012 15.1 0.1 5.2 5 1 0 5 5 5 2 Kelch motif DUF999 PF06198.6 GAM19781.1 - 0.024 14.4 0.2 0.07 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Kelch_5 PF13854.1 GAM19781.1 - 0.035 14.0 15.8 1.8 8.6 0.7 4.3 3 1 1 4 4 4 0 Kelch motif Kelch_2 PF07646.10 GAM19781.1 - 6.4 6.7 9.8 33 4.4 1.3 4.4 4 1 0 4 4 4 0 Kelch motif Zip PF02535.17 GAM19782.1 - 2.4e-44 151.6 10.4 3e-44 151.3 7.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2970 PF11174.3 GAM19782.1 - 0.025 14.1 0.1 0.025 14.1 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) DUF914 PF06027.7 GAM19783.1 - 2.7e-104 348.6 23.9 3.5e-104 348.2 16.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 GAM19783.1 - 1.8e-08 33.6 22.5 2.3e-08 33.3 15.6 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM19783.1 - 1.2e-07 31.7 32.3 0.00072 19.5 8.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 GAM19783.1 - 2.2e-06 26.9 14.6 0.00011 21.4 4.7 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.11 GAM19783.1 - 5.7e-05 22.8 26.8 0.001 18.7 9.1 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 GAM19783.1 - 0.002 18.2 26.8 0.0021 18.2 5.6 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Pex24p PF06398.6 GAM19783.1 - 0.1 11.4 3.0 0.77 8.4 1.2 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Mg_trans_NIPA PF05653.9 GAM19783.1 - 0.13 11.2 14.5 0.0073 15.3 4.1 2.1 1 1 1 2 2 2 0 Magnesium transporter NIPA DUF2273 PF10031.4 GAM19783.1 - 0.42 10.2 6.4 3 7.5 0.1 3.3 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) SET PF00856.23 GAM19784.1 - 2.3e-08 34.5 0.0 4.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-C3HC4_3 PF13920.1 GAM19784.1 - 0.00012 21.6 3.4 0.00023 20.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 GAM19784.1 - 0.012 15.4 0.5 0.027 14.2 0.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RL11D PF11088.3 GAM19785.1 - 1.1 9.1 6.3 5.1 6.9 0.3 2.5 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 RL11D PF11088.3 GAM19786.1 - 0.055 13.2 1.2 0.16 11.8 0.8 1.8 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Pentapeptide_4 PF13599.1 GAM19786.1 - 0.22 11.3 6.7 2 8.2 2.9 3.5 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Chlam_PMP PF02415.12 GAM19787.1 - 6.9e-10 38.5 35.3 0.012 15.8 0.1 9.4 10 0 0 10 10 10 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat hEGF PF12661.2 GAM19787.1 - 0.0042 17.0 3.1 0.018 15.1 2.1 2.2 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.22 GAM19787.1 - 0.97 9.4 9.4 0.077 12.9 1.8 2.7 2 0 0 2 2 2 0 EGF-like domain CN_hydrolase PF00795.17 GAM19788.1 - 2e-17 63.1 0.0 3.5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase G-patch_2 PF12656.2 GAM19789.1 - 4.7e-26 90.4 0.1 4.7e-26 90.4 0.1 2.1 2 0 0 2 2 2 1 DExH-box splicing factor binding site KOW PF00467.24 GAM19789.1 - 3.4e-10 39.2 4.6 0.0023 17.5 0.0 3.6 3 0 0 3 3 3 3 KOW motif G-patch PF01585.18 GAM19789.1 - 7.1e-07 28.9 0.8 1.7e-06 27.6 0.6 1.7 1 0 0 1 1 1 1 G-patch domain YajC PF02699.10 GAM19789.1 - 0.21 11.3 1.6 0.34 10.6 0.3 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit GST_N_3 PF13417.1 GAM19790.1 - 7.1e-07 29.3 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM19790.1 - 1e-06 28.8 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM19790.1 - 3.8e-05 23.6 0.0 9.8e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM19790.1 - 0.00044 20.1 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM19790.1 - 0.00084 19.7 0.0 0.003 18.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM19790.1 - 0.0022 17.8 0.0 0.011 15.5 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F_actin_bind PF08919.5 GAM19791.1 - 0.0053 16.4 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 F-actin binding FACT-Spt16_Nlob PF14826.1 GAM19791.1 - 0.0064 16.0 1.7 0.086 12.3 0.2 2.2 1 1 1 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain IFT57 PF10498.4 GAM19791.1 - 0.053 12.2 0.2 0.19 10.4 0.1 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 PH PF00169.24 GAM19792.1 - 5e-11 42.7 0.1 4.2e-10 39.7 0.0 2.4 2 1 1 3 3 3 1 PH domain Ank_2 PF12796.2 GAM19793.1 - 0.00077 19.7 1.5 0.016 15.4 0.5 3.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) DUF3447 PF11929.3 GAM19793.1 - 0.013 15.2 6.1 0.18 11.6 0.2 4.5 4 2 1 5 5 5 0 Domain of unknown function (DUF3447) Ank_4 PF13637.1 GAM19793.1 - 0.069 13.6 4.0 4.3 7.9 0.0 4.9 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19793.1 - 1.6 9.2 7.3 2.3 8.7 0.1 4.9 7 0 0 7 7 7 0 Ankyrin repeat Glyco_hydro_65m PF03632.10 GAM19795.1 - 1.1e-82 277.6 0.4 1e-81 274.4 0.3 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.4 GAM19795.1 - 1.4e-14 53.3 0.0 1.7e-12 46.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) ATP-grasp_2 PF08442.5 GAM19796.1 - 8e-16 58.0 0.0 2.9e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAM19796.1 - 0.055 13.1 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain LOH1CR12 PF10158.4 GAM19797.1 - 0.00015 21.5 0.1 0.00015 21.5 0.1 1.8 2 0 0 2 2 2 1 Tumour suppressor protein DEAD PF00270.24 GAM19798.1 - 2.9e-42 144.0 0.3 1.1e-41 142.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM19798.1 - 2.7e-26 91.2 0.2 6.5e-26 90.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM19798.1 - 2.7e-05 23.0 0.0 4.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 GAM19798.1 - 0.0044 17.1 0.2 0.028 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM19798.1 - 0.013 15.2 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Ank_2 PF12796.2 GAM19800.1 - 5.5e-06 26.6 0.5 5.1e-05 23.5 0.0 2.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19800.1 - 0.0037 17.3 0.2 1.5 9.3 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAM19800.1 - 0.0058 17.1 0.2 0.21 12.1 0.2 3.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19800.1 - 0.019 14.7 0.0 17 5.4 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat ER PF01133.12 GAM19801.1 - 9.4e-41 137.7 1.7 1.2e-40 137.4 0.4 1.8 2 0 0 2 2 2 1 Enhancer of rudimentary DUF830 PF05708.7 GAM19801.1 - 0.065 13.2 0.0 0.35 10.8 0.0 2.0 1 1 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) TIG PF01833.19 GAM19802.1 - 2.5e-08 33.7 16.0 1.3e-06 28.3 4.5 2.4 1 1 1 2 2 2 2 IPT/TIG domain TMEM154 PF15102.1 GAM19802.1 - 0.00014 21.5 2.4 0.00014 21.5 1.7 2.2 2 1 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.1 GAM19802.1 - 0.00023 20.7 1.1 0.0004 19.9 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3377 PF11857.3 GAM19802.1 - 0.00027 20.5 0.5 0.00075 19.0 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF2207 PF09972.4 GAM19802.1 - 0.0013 17.4 0.0 0.0022 16.6 0.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Amnionless PF14828.1 GAM19802.1 - 0.014 13.9 0.1 0.02 13.4 0.1 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.1 GAM19802.1 - 0.018 15.4 0.5 0.038 14.3 0.4 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 GAM19802.1 - 0.033 12.4 0.0 0.042 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Sec66 PF09802.4 GAM19802.1 - 0.041 13.2 0.1 0.061 12.7 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Rifin_STEVOR PF02009.11 GAM19802.1 - 1.1 8.7 4.3 1.5 8.3 2.7 1.5 1 1 0 1 1 1 0 Rifin/stevor family IMD PF08397.6 GAM19803.1 - 4.8e-16 58.7 5.5 6.6e-16 58.2 3.8 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.23 GAM19803.1 - 3.4e-14 51.9 0.0 6e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM19803.1 - 6.6e-11 41.6 0.0 1.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM19803.1 - 6.9e-08 31.8 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TSC22 PF01166.13 GAM19803.1 - 2.3 8.2 9.9 0.13 12.2 1.8 2.7 3 1 0 3 3 3 0 TSC-22/dip/bun family Mitofilin PF09731.4 GAM19803.1 - 2.9 6.4 14.1 3.5 6.1 9.2 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein ApoL PF05461.6 GAM19803.1 - 6.1 5.9 11.5 0.56 9.4 1.1 2.8 2 1 1 3 3 3 0 Apolipoprotein L Ribosomal_L38e PF01781.13 GAM19804.1 - 2.3e-25 88.1 3.7 2.9e-25 87.8 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family LIM PF00412.17 GAM19805.1 - 9.1e-12 44.8 3.5 1.9e-11 43.8 2.4 1.5 1 0 0 1 1 1 1 LIM domain zf-met PF12874.2 GAM19805.1 - 0.19 11.9 6.1 2.3 8.5 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type G8 PF10162.4 GAM19806.1 - 3e-23 81.9 0.1 7.6e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 G8 domain DUF1576 PF07613.6 GAM19807.1 - 0.087 12.3 2.2 0.11 12.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Sdh_cyt PF01127.17 GAM19807.1 - 5.3 6.9 8.0 8.3 6.2 5.5 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit EGF_2 PF07974.8 GAM19809.1 - 0.00037 20.5 10.8 0.00037 20.5 7.5 3.3 3 0 0 3 3 3 2 EGF-like domain EB PF01683.13 GAM19809.1 - 0.0014 18.6 5.7 0.0014 18.6 3.9 3.7 1 1 1 2 2 2 1 EB module EGF PF00008.22 GAM19809.1 - 0.011 15.7 8.8 0.011 15.7 6.1 2.8 2 0 0 2 2 2 0 EGF-like domain EB PF01683.13 GAM19810.1 - 0.00042 20.3 2.4 0.00042 20.3 1.7 2.9 4 0 0 4 4 4 1 EB module G8 PF10162.4 GAM19811.1 - 1.8e-21 76.1 0.1 4.4e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 G8 domain Ank_2 PF12796.2 GAM19812.1 - 7.3e-20 71.0 15.3 2.1e-07 31.1 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM19812.1 - 4.5e-16 58.4 9.5 0.00031 20.8 0.2 6.5 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM19812.1 - 5.4e-15 55.4 5.4 0.00029 21.2 0.0 5.3 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19812.1 - 3.2e-11 42.3 4.6 3.1 8.2 0.0 7.1 4 1 3 7 7 7 4 Ankyrin repeat Ank PF00023.25 GAM19812.1 - 6.7e-10 38.2 1.4 2.7 7.9 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat DUF4388 PF14332.1 GAM19812.1 - 0.0022 17.8 0.0 9.8 6.0 0.0 4.4 3 2 1 4 4 4 1 Domain of unknown function (DUF4388) zf-C2HC PF01530.13 GAM19812.1 - 5.6 6.7 13.7 6.1 6.6 0.3 4.2 5 0 0 5 5 5 0 Zinc finger, C2HC type Cir_Bir_Yir PF06022.6 GAM19813.1 - 0.047 12.9 0.5 0.046 12.9 0.4 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Syntaxin_2 PF14523.1 GAM19813.1 - 0.14 12.1 2.3 0.19 11.7 1.3 1.3 1 1 0 1 1 1 0 Syntaxin-like protein NPV_P10 PF05531.7 GAM19814.1 - 0.7 10.1 3.2 0.93 9.7 2.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YuiB PF14068.1 GAM19814.1 - 0.84 9.9 4.0 0.88 9.9 2.8 1.1 1 0 0 1 1 1 0 Putative membrane protein Amastin PF07344.6 GAM19815.1 - 1.2 8.7 5.0 1.1 8.8 3.5 1.1 1 0 0 1 1 1 0 Amastin surface glycoprotein Dymeclin PF09742.4 GAM19817.1 - 1.8e-85 287.4 20.4 2.3e-85 287.1 14.2 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 GAM19817.1 - 0.0093 13.7 26.1 0.0018 16.0 12.7 2.5 2 1 1 3 3 3 2 High-temperature-induced dauer-formation protein Glyco_transf_10 PF00852.14 GAM19817.1 - 0.044 12.3 0.2 0.068 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) DUF1084 PF06454.6 GAM19818.1 - 6.8e-11 41.7 20.7 1.4e-10 40.7 14.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) tRNA-synt_2b PF00587.20 GAM19819.1 - 4.1e-30 104.6 0.0 6.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 GAM19819.1 - 6.2e-13 48.7 6.8 9.9e-13 48.0 4.7 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 GAM19819.1 - 0.16 10.8 2.1 0.56 9.1 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SKG6 PF08693.5 GAM19820.1 - 0.0096 15.2 2.2 0.024 13.9 1.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3377 PF11857.3 GAM19820.1 - 0.021 14.4 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Mito_carr PF00153.22 GAM19821.1 - 4.1e-67 221.9 5.5 8.8e-26 89.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.24 GAM19822.1 - 9.6e-08 32.1 1.7 3.3e-07 30.4 1.2 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM19822.1 - 0.0046 17.1 1.9 0.0046 17.1 1.3 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Rac1 PF09632.5 GAM19822.1 - 0.044 12.8 1.4 5 6.1 0.2 2.8 2 0 0 2 2 2 0 Rac1-binding domain IF4E PF01652.13 GAM19823.1 - 9.4e-55 184.6 0.8 9.4e-55 184.6 0.6 1.6 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E Dicty_REP PF05086.7 GAM19823.1 - 0.00095 17.0 10.7 0.0012 16.7 7.4 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein PIH1 PF08190.7 GAM19823.1 - 1 8.7 10.9 1.4 8.3 7.6 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RP-C_C PF11800.3 GAM19823.1 - 2.5 7.7 8.5 3.8 7.1 5.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Menin PF05053.8 GAM19823.1 - 2.7 6.0 10.9 3.5 5.6 7.5 1.1 1 0 0 1 1 1 0 Menin POX PF07526.6 GAM19823.1 - 3.5 7.8 9.3 7.4 6.7 6.4 1.6 1 1 0 1 1 1 0 Associated with HOX Pox_RNA_Pol_19 PF05320.7 GAM19823.1 - 7.7 6.2 9.4 13 5.4 6.5 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Peptidase_M16_C PF05193.16 GAM19824.1 - 3.1e-30 105.2 0.3 1.3e-29 103.2 0.1 2.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM19824.1 - 8.1e-26 90.5 0.0 1.9e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Hom_end_hint PF05203.11 GAM19824.1 - 0.0063 16.2 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Hom_end-associated Hint PA14 PF07691.7 GAM19825.1 - 4.3e-08 32.9 0.1 4.3e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.13 GAM19825.1 - 2e-05 24.3 19.7 0.00022 20.9 2.3 10.1 11 1 0 11 11 11 4 Dictyostelium (slime mold) repeat EGF_2 PF07974.8 GAM19826.1 - 2.6e-10 40.2 49.2 5e-05 23.3 9.3 3.5 2 1 1 3 3 3 3 EGF-like domain Sporozoite_P67 PF05642.6 GAM19826.1 - 0.13 10.1 1.7 0.19 9.5 1.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tir_receptor_C PF07489.6 GAM19826.1 - 9.4 5.9 8.4 20 4.8 5.9 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus FNIP PF05725.7 GAM19827.1 - 2.6e-60 200.1 41.2 7.9e-14 51.3 0.5 9.0 5 3 5 10 10 10 9 FNIP Repeat FNIP PF05725.7 GAM19828.1 - 9.4e-29 99.1 9.6 3.2e-10 39.8 0.1 3.5 1 1 0 3 3 3 3 FNIP Repeat FNIP PF05725.7 GAM19829.1 - 5.7e-57 189.4 36.9 3.9e-11 42.7 0.1 9.9 6 2 5 11 11 11 10 FNIP Repeat GPI-anchored PF10342.4 GAM19830.1 - 0.00053 20.4 1.9 0.0013 19.1 1.3 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Inhibitor_I67 PF11405.3 GAM19830.1 - 0.065 13.2 0.7 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Bromelain inhibitor VI PPE PF00823.14 GAM19830.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 PPE family 2-Hacid_dh_C PF02826.14 GAM19831.1 - 2e-50 170.4 0.0 4.3e-50 169.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM19831.1 - 1.3e-33 115.3 0.0 1.8e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM19831.1 - 3.4e-05 23.7 0.1 7.1e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 GAM19831.1 - 0.0014 18.0 0.1 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.1 GAM19831.1 - 0.0028 17.9 0.0 0.0087 16.3 0.0 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 GAM19831.1 - 0.0047 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 GAM19831.1 - 0.02 14.2 0.1 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 GAM19831.1 - 0.032 13.8 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PAP2 PF01569.16 GAM19832.1 - 1.4e-12 47.3 5.8 1.4e-12 47.3 4.0 3.2 2 2 1 3 3 3 2 PAP2 superfamily DUF4231 PF14015.1 GAM19832.1 - 3.9 7.4 6.7 34 4.4 0.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) SAPS PF04499.10 GAM19833.1 - 4e-70 236.7 2.2 9.9e-42 143.1 0.1 2.3 1 1 1 2 2 2 2 SIT4 phosphatase-associated protein EF1_GNE PF00736.14 GAM19833.1 - 1.4e-28 98.4 1.3 3.4e-28 97.1 0.9 1.7 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Sgf11 PF08209.6 GAM19834.1 - 5.1e-10 38.5 0.2 5.1e-10 38.5 0.1 1.7 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) DUF3268 PF11672.3 GAM19834.1 - 0.023 14.7 0.5 0.056 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) SPA PF08616.5 GAM19836.1 - 3.1e-13 49.4 0.1 5.3e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAM19836.1 - 3e-10 39.1 0.4 0.00022 19.8 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 GAM19836.1 - 2.6e-09 36.7 0.4 5.7e-09 35.6 0.3 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 GAM19836.1 - 0.0013 18.4 0.1 0.0023 17.6 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain MatE PF01554.13 GAM19837.1 - 0.9 9.1 8.3 1.4 8.4 5.7 1.4 1 0 0 1 1 1 0 MatE Lipoprotein_19 PF13617.1 GAM19837.1 - 1.6 8.3 4.7 3.5 7.3 3.2 1.5 1 0 0 1 1 1 0 YnbE-like lipoprotein Glycogen_syn PF05693.8 GAM19838.1 - 5.1e-269 893.8 0.0 5.1e-269 893.8 0.0 1.4 2 0 0 2 2 2 1 Glycogen synthase Glycos_transf_1 PF00534.15 GAM19838.1 - 3e-06 26.7 0.0 0.00029 20.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 GAM19838.1 - 3.6e-05 23.3 0.1 7.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Kelch_6 PF13964.1 GAM19839.1 - 2e-11 43.5 7.3 0.00032 20.7 0.1 4.7 3 1 1 4 4 4 4 Kelch motif Kelch_4 PF13418.1 GAM19839.1 - 0.0085 15.8 9.7 1.7 8.4 0.0 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM19839.1 - 0.01 16.0 3.8 1.5 9.0 0.1 3.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM19839.1 - 1.2 8.7 6.9 37 3.9 0.0 4.4 5 0 0 5 5 5 0 Kelch motif PAP2 PF01569.16 GAM19840.1 - 9.5e-09 35.0 2.4 9.5e-09 35.0 1.7 2.6 1 1 2 3 3 3 1 PAP2 superfamily Pkinase PF00069.20 GAM19841.1 - 9.7e-69 231.3 0.0 1.3e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19841.1 - 2.9e-48 164.2 0.0 5.2e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM19841.1 - 9.4e-15 54.7 0.2 2.7e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 GAM19841.1 - 1.6e-14 53.9 0.1 3e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 GAM19841.1 - 1.1e-05 24.5 0.0 5.6e-05 22.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like PH_11 PF15413.1 GAM19841.1 - 0.00014 22.0 2.8 0.012 15.8 1.9 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM19841.1 - 0.00025 21.0 0.2 0.00079 19.4 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 GAM19841.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1491 PF07372.7 GAM19841.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) HAD_2 PF13419.1 GAM19842.1 - 2.6e-16 60.3 0.0 8.5e-16 58.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM19842.1 - 2.1e-08 34.8 0.0 9.5e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM19842.1 - 2.2e-05 24.0 0.0 3.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PNK3P PF08645.6 GAM19842.1 - 9.7e-05 21.8 0.0 0.00053 19.4 0.0 2.0 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase_6 PF13344.1 GAM19842.1 - 0.021 14.7 0.3 0.16 11.8 0.0 2.7 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3895 PF13034.1 GAM19842.1 - 0.085 12.3 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) Kelch_6 PF13964.1 GAM19843.1 - 1.8e-15 56.3 6.2 7.2e-07 29.1 0.0 5.4 3 2 2 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM19843.1 - 5.3e-13 48.5 2.3 3.4e-08 33.1 0.0 5.6 5 1 0 5 5 5 1 Galactose oxidase, central domain zf-B_box PF00643.19 GAM19843.1 - 9.2e-10 38.2 5.3 2e-09 37.2 3.6 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.20 GAM19843.1 - 5e-09 35.5 1.1 0.00094 18.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM19843.1 - 4.1e-08 32.6 0.0 0.004 16.8 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM19843.1 - 4.2e-08 33.1 3.8 0.0003 20.8 0.0 5.1 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM19843.1 - 0.019 14.9 8.1 3.1 7.8 0.0 5.2 6 0 0 6 6 6 0 Kelch motif SKIP_SNW PF02731.10 GAM19843.1 - 0.097 12.1 1.6 2.6 7.4 1.6 2.3 2 0 0 2 2 2 0 SKIP/SNW domain IBR PF01485.16 GAM19843.1 - 0.27 11.1 3.6 0.69 9.8 2.5 1.6 1 0 0 1 1 1 0 IBR domain PAT1 PF09770.4 GAM19843.1 - 3.2 5.8 18.3 4.4 5.4 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 GAM19845.1 - 1.6e-19 69.2 0.2 3.8e-12 45.6 0.1 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19845.1 - 7.7e-14 51.2 0.0 4.1e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19845.1 - 9.9e-14 51.0 0.0 1.7e-06 27.8 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ELMO_CED12 PF04727.8 GAM19848.1 - 1.9e-22 79.6 0.1 7.4e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family CX PF01705.14 GAM19848.1 - 0.23 11.4 0.3 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 CX module FNIP PF05725.7 GAM19849.1 - 3.1e-69 228.6 21.8 1.8e-13 50.2 0.1 8.0 6 1 3 9 9 9 9 FNIP Repeat Cullin_binding PF03556.10 GAM19850.1 - 7.5e-32 109.9 1.1 1.6e-31 108.8 0.8 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 GAM19850.1 - 4.5e-07 29.2 0.0 9.3e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain EF-hand_6 PF13405.1 GAM19850.1 - 0.047 13.5 0.2 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain RhoGEF PF00621.15 GAM19851.1 - 4.1e-40 137.5 7.7 6e-40 137.0 5.3 1.2 1 0 0 1 1 1 1 RhoGEF domain Ank_2 PF12796.2 GAM19853.1 - 2e-07 31.2 0.0 0.036 14.4 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19853.1 - 8.8e-05 22.3 0.8 13 6.4 0.0 6.3 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.25 GAM19853.1 - 0.0043 16.7 0.1 3 7.8 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 GAM19853.1 - 0.05 14.1 1.5 32 5.1 0.0 4.5 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM19854.1 - 0.0031 17.8 0.1 4.6 7.6 0.0 4.0 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM19855.1 - 1.5e-07 31.6 0.3 0.005 17.1 0.1 4.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19855.1 - 0.00013 21.8 1.2 7.1 7.1 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.25 GAM19855.1 - 0.00093 18.8 3.1 0.026 14.3 0.1 4.5 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 GAM19855.1 - 0.003 17.7 0.2 3.7 7.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) DUF1858 PF08984.6 GAM19855.1 - 0.012 15.1 0.0 3.5 7.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) FANCI_S4 PF14678.1 GAM19855.1 - 0.12 11.4 1.7 0.13 11.3 0.1 1.7 2 0 0 2 2 2 0 FANCI solenoid 4 Ank_3 PF13606.1 GAM19857.1 - 6.2 7.3 7.4 52 4.5 0.3 4.9 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.2 GAM19858.1 - 4.6e-07 30.1 0.1 0.0097 16.2 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19858.1 - 0.0017 18.3 4.4 1.5 9.3 0.4 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAM19858.1 - 0.15 12.5 1.2 21 5.7 0.0 4.2 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM19858.1 - 5 7.1 13.0 0.84 9.5 0.7 4.2 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.2 GAM19859.1 - 0.0047 17.2 0.0 0.059 13.7 0.0 2.6 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) TSP_C PF05735.7 GAM19859.1 - 0.066 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Thrombospondin C-terminal region Ank_2 PF12796.2 GAM19860.1 - 5.8e-07 29.7 1.8 0.0099 16.2 0.1 4.7 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19860.1 - 0.0074 16.4 4.9 10 6.7 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAM19860.1 - 0.034 14.6 3.0 30 5.2 0.0 5.1 4 1 1 5 5 4 0 Ankyrin repeats (many copies) RXT2_N PF08595.6 GAM19860.1 - 0.1 12.4 2.7 0.28 10.9 1.9 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Ank PF00023.25 GAM19860.1 - 0.16 11.8 6.9 0.35 10.7 0.1 4.3 5 0 0 5 5 5 0 Ankyrin repeat Nucleoplasmin PF03066.10 GAM19860.1 - 9.1 5.7 9.3 0.82 9.1 3.0 1.7 2 0 0 2 2 2 0 Nucleoplasmin Ank_2 PF12796.2 GAM19861.1 - 2.8e-07 30.7 0.0 0.085 13.2 0.0 5.2 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19861.1 - 0.064 13.5 6.0 1.4 9.3 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat Guanylate_cyc PF00211.15 GAM19862.1 - 1.7e-108 360.0 4.4 8.1e-57 191.5 0.4 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CH PF00307.26 GAM19863.1 - 7.1e-34 116.0 0.8 3.7e-17 62.3 0.1 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM19863.1 - 3.3e-06 26.6 1.4 1.8e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 CAMSAP CH domain Kelch_6 PF13964.1 GAM19864.1 - 2.8e-43 144.3 9.7 1.8e-08 34.2 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM19864.1 - 1.7e-38 129.8 8.2 1.1e-08 34.4 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 GAM19864.1 - 1.3e-36 124.0 18.5 5.7e-09 35.6 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM19864.1 - 3.2e-35 119.5 6.9 1.3e-05 25.0 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 GAM19864.1 - 5.6e-35 118.7 7.8 1.5e-08 34.5 0.0 7.4 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM19864.1 - 2.2e-34 115.8 15.7 2.4e-07 30.2 0.2 6.8 6 1 0 6 6 6 6 Kelch motif F-box PF00646.28 GAM19864.1 - 6.3e-05 22.5 0.1 0.00019 20.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM19864.1 - 8e-05 22.2 0.2 0.00024 20.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like DUF1668 PF07893.8 GAM19864.1 - 0.04 13.0 4.2 0.082 12.0 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1668) Spidroin_MaSp PF11260.3 GAM19864.1 - 0.59 10.2 2.2 1.4 9.0 1.5 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Ank_2 PF12796.2 GAM19865.1 - 9.9e-07 29.0 0.4 0.16 12.3 0.0 4.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19865.1 - 0.013 15.7 1.3 14 6.2 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat Peptidase_C1 PF00112.18 GAM19866.1 - 1.6e-61 207.9 10.9 2e-61 207.7 7.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 GAM19866.1 - 2.4 6.5 6.1 5 5.5 0.1 2.4 2 0 0 2 2 2 0 Peptidase C1-like family Clathrin PF00637.15 GAM19874.1 - 0.1 12.1 0.9 0.16 11.5 0.6 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS BRX PF08381.6 GAM19874.1 - 0.16 11.0 1.3 0.41 9.7 0.2 2.0 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 TPR_11 PF13414.1 GAM19875.1 - 1.6e-13 50.1 9.9 1.3e-10 40.7 1.5 2.6 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM19875.1 - 1.2e-10 40.5 13.6 4.8e-05 22.7 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM19875.1 - 2.7e-09 36.2 11.4 0.0012 18.6 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat SET PF00856.23 GAM19875.1 - 6.4e-08 33.0 0.2 1.3e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 SET domain TPR_8 PF13181.1 GAM19875.1 - 0.00012 21.5 14.5 0.093 12.5 0.8 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM19875.1 - 0.00041 20.2 8.5 0.0097 15.8 1.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM19875.1 - 0.0033 17.9 1.0 3.6 8.4 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM19875.1 - 0.01 15.9 7.8 0.032 14.3 5.4 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAM19875.1 - 0.013 15.2 3.8 0.32 10.9 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM19875.1 - 0.026 14.7 2.9 7.9 6.9 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 GAM19875.1 - 0.2 11.5 3.6 4.5 7.2 0.1 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 GAM19875.1 - 0.48 11.1 4.8 3.3 8.5 0.1 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM19875.1 - 0.72 10.2 6.6 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM19875.1 - 5.7 7.6 7.4 9 6.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AMP-binding PF00501.23 GAM19876.1 - 5.8e-85 285.1 0.0 7.1e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM19876.1 - 9.7e-17 61.6 0.0 2.2e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_21 PF09976.4 GAM19876.1 - 0.071 13.0 0.5 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 GAM19877.1 - 8.9e-17 60.4 0.1 1.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19877.1 - 2.7e-13 49.6 0.0 4.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19877.1 - 9.5e-05 22.1 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMSR PF01625.16 GAM19878.1 - 7.9e-61 204.4 2.8 9.6e-61 204.2 2.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.20 GAM19879.1 - 3.6e-64 216.4 0.0 8.2e-64 215.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19879.1 - 9.8e-42 142.8 0.0 1.9e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM19879.1 - 2.1e-07 30.2 0.0 3.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HALZ PF02183.13 GAM19879.1 - 0.00021 20.9 1.7 0.00032 20.3 0.3 2.0 2 0 0 2 2 2 1 Homeobox associated leucine zipper Seadorna_VP7 PF07387.6 GAM19879.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DivIC PF04977.10 GAM19879.1 - 0.15 11.5 1.0 5.4 6.5 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator TPR_19 PF14559.1 GAM19880.1 - 7.1e-08 32.6 4.3 0.0016 18.7 0.0 4.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM19880.1 - 7.4e-08 31.9 1.3 0.0031 17.1 0.1 3.6 4 0 0 4 4 4 2 TPR repeat NARP1 PF12569.3 GAM19880.1 - 8.5e-07 28.1 7.7 0.0016 17.2 0.2 2.7 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 GAM19880.1 - 3.2e-06 27.6 0.1 0.0056 17.3 0.0 3.5 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM19880.1 - 8.1e-06 25.6 3.0 0.00028 20.7 0.5 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM19880.1 - 2.6e-05 23.7 4.1 0.01 15.6 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM19880.1 - 5.5e-05 23.2 10.2 0.6 10.2 0.1 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM19880.1 - 0.0002 21.1 1.4 0.0018 18.0 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM19880.1 - 0.0017 17.9 6.6 0.027 14.0 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM19880.1 - 0.0045 16.6 1.2 0.02 14.6 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM19880.1 - 0.0053 17.2 0.1 12 6.8 0.0 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM19880.1 - 0.0074 16.6 2.4 55 4.5 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAM19880.1 - 0.029 14.5 0.1 0.067 13.4 0.1 1.6 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation DUF445 PF04286.7 GAM19880.1 - 4.1 6.8 6.2 13 5.2 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) NARP1 PF12569.3 GAM19881.1 - 8.3e-21 74.3 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 RHS_repeat PF05593.9 GAM19881.1 - 0.098 12.8 0.4 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 RHS Repeat HCaRG PF07258.9 GAM19882.1 - 3.5e-27 95.0 7.3 5e-27 94.5 5.1 1.3 1 1 0 1 1 1 1 HCaRG protein Atg8 PF02991.11 GAM19884.1 - 6.8e-32 109.5 0.1 8.2e-32 109.2 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 GAM19884.1 - 0.0012 19.0 0.1 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HEAT_2 PF13646.1 GAM19885.1 - 1.5e-07 31.6 0.1 0.0097 16.1 0.0 6.0 6 2 1 7 7 7 1 HEAT repeats Arm PF00514.18 GAM19885.1 - 5e-06 26.1 5.2 0.0054 16.5 0.0 7.2 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAM19885.1 - 0.0076 16.2 1.5 2.2 8.5 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 GAM19885.1 - 0.017 15.6 0.1 13 6.4 0.0 4.6 3 1 1 4 4 4 0 HEAT-like repeat Peptidase_M16 PF00675.15 GAM19886.1 - 4.3e-54 182.3 0.1 9.3e-54 181.2 0.1 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAM19886.1 - 1.5e-36 125.8 0.0 3e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Mei4 PF13971.1 GAM19886.1 - 8.6e-05 21.6 0.6 0.2 10.5 0.1 2.3 2 0 0 2 2 2 2 Meiosis-specific protein Mei4 Thioredoxin PF00085.15 GAM19887.1 - 8.5e-17 60.7 0.0 1.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 GAM19887.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 GAM19887.1 - 0.019 15.1 0.0 0.25 11.5 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAM19887.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Ribosomal_L36e PF01158.13 GAM19888.1 - 6.6e-33 112.6 6.0 7.2e-33 112.4 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DKCLD PF08068.7 GAM19888.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain 4HB_MCP_1 PF12729.2 GAM19888.1 - 0.05 12.9 0.1 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CKS PF01111.14 GAM19889.1 - 1.4e-31 108.1 2.6 1.4e-31 108.1 1.8 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit adh_short PF00106.20 GAM19890.1 - 1.7e-28 99.5 0.2 2.8e-28 98.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM19890.1 - 2.3e-21 76.6 0.0 3.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM19890.1 - 2.1e-10 40.5 0.1 3.4e-10 39.8 0.1 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 GAM19890.1 - 0.00028 21.1 0.1 0.00065 19.9 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.12 GAM19890.1 - 0.00089 19.6 0.1 0.0017 18.7 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 GAM19890.1 - 0.0016 17.9 0.0 0.011 15.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM19890.1 - 0.0019 17.3 0.1 0.065 12.3 0.0 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 GAM19890.1 - 0.0024 17.9 0.1 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 GAM19890.1 - 0.021 14.4 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 GAM19890.1 - 0.048 13.5 1.6 0.085 12.6 0.4 1.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 GAM19890.1 - 0.051 13.5 0.1 0.094 12.7 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 GAM19890.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 GAM19890.1 - 0.095 13.1 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acid_phosphat_B PF03767.9 GAM19890.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Ras PF00071.17 GAM19891.1 - 3e-38 130.7 0.0 3.7e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19891.1 - 3.2e-18 66.3 0.0 5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19891.1 - 2.3e-16 59.5 0.0 3.2e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM19891.1 - 1.3e-08 34.2 0.0 1.7e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM19891.1 - 1.4e-06 27.6 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAM19891.1 - 1.6e-05 24.4 0.0 0.00013 21.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 GAM19891.1 - 2.9e-05 22.9 5.0 0.015 14.0 0.0 2.9 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 GAM19891.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 GAM19891.1 - 0.00055 19.4 0.0 0.098 12.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 GAM19891.1 - 0.0019 17.7 0.2 0.014 14.9 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 GAM19891.1 - 0.086 12.6 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 GAM19891.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Kelch_1 PF01344.20 GAM19892.1 - 8.8e-41 137.2 15.8 2.4e-08 33.3 0.9 7.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM19892.1 - 1.7e-39 132.3 11.8 1.3e-08 34.6 0.1 7.5 3 1 4 7 7 7 6 Kelch motif Kelch_4 PF13418.1 GAM19892.1 - 4.1e-35 119.3 3.1 5e-08 32.5 0.1 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM19892.1 - 3.2e-23 81.2 0.1 3.8e-06 26.9 0.0 6.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM19892.1 - 8.7e-12 44.7 15.9 0.00011 22.0 0.0 7.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 GAM19892.1 - 7.1e-06 25.5 4.9 0.16 11.8 0.1 6.3 6 0 0 6 6 6 1 Kelch motif zf-B_box PF00643.19 GAM19892.1 - 0.00018 21.3 7.4 0.00018 21.3 5.2 3.4 3 0 0 3 3 3 1 B-box zinc finger zf-C3HC4_4 PF15227.1 GAM19892.1 - 0.0088 15.8 2.3 0.0088 15.8 1.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 GAM19892.1 - 0.75 9.4 16.8 0.014 15.0 4.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM19892.1 - 3.3 7.5 9.8 0.04 13.6 0.7 2.5 2 0 0 2 2 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 GAM19892.1 - 5.5 6.8 16.0 0.074 12.7 4.2 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 GAM19892.1 - 6.4 6.6 15.8 0.016 15.0 3.8 2.1 2 0 0 2 2 1 0 Ring finger domain SapB_1 PF05184.10 GAM19893.1 - 0.11 12.3 0.1 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 Kelch_6 PF13964.1 GAM19894.1 - 4.4e-11 42.4 3.8 0.017 15.2 0.0 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM19894.1 - 1.7e-07 30.8 5.3 0.0012 18.5 0.0 4.8 4 1 0 4 4 4 2 Galactose oxidase, central domain zf-B_box PF00643.19 GAM19894.1 - 4e-07 29.8 6.9 7.7e-07 28.9 4.8 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.20 GAM19894.1 - 1.1e-06 28.0 5.9 0.0019 17.7 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.1 GAM19894.1 - 1.6e-05 24.9 3.5 0.045 13.9 0.0 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM19894.1 - 0.00033 20.5 3.5 1.9 8.5 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM19894.1 - 0.014 15.1 4.9 19 5.2 0.1 3.7 2 1 1 3 3 3 0 Kelch motif DUF2935 PF11155.3 GAM19894.1 - 0.16 12.0 3.5 0.37 10.8 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) YlbD_coat PF14071.1 GAM19894.1 - 0.35 10.9 7.0 2 8.4 1.9 2.7 3 0 0 3 3 3 0 Putative coat protein DUF1084 PF06454.6 GAM19896.1 - 1.3e-73 247.5 19.1 1.6e-73 247.2 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) COPI_assoc PF08507.5 GAM19897.1 - 1.7e-08 34.2 2.2 2.4e-08 33.7 1.5 1.2 1 0 0 1 1 1 1 COPI associated protein DUF308 PF03729.8 GAM19897.1 - 0.0061 16.5 9.9 0.1 12.6 0.1 2.6 2 1 1 3 3 3 3 Short repeat of unknown function (DUF308) PEN-2 PF10251.4 GAM19897.1 - 0.014 15.5 0.9 0.033 14.4 0.1 2.0 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF4345 PF14248.1 GAM19897.1 - 0.058 12.8 3.9 0.091 12.2 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) SIT PF15330.1 GAM19897.1 - 0.11 12.7 0.0 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF202 PF02656.10 GAM19897.1 - 1.8 8.8 4.7 16 5.8 3.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF4131 PF13567.1 GAM19897.1 - 6 6.2 9.5 8.5 5.7 1.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Synaptobrevin PF00957.16 GAM19898.1 - 2.7e-25 87.7 3.6 3e-25 87.6 2.5 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2721 PF11026.3 GAM19898.1 - 0.0052 16.4 0.2 0.0063 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) ODV-E18 PF10717.4 GAM19898.1 - 0.013 14.9 1.9 0.021 14.2 1.3 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3753 PF12575.3 GAM19898.1 - 0.017 14.9 1.2 0.031 14.0 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Spatacsin_C PF14649.1 GAM19898.1 - 0.023 13.5 0.0 0.025 13.4 0.0 1.0 1 0 0 1 1 1 0 Spatacsin C-terminus Sarcoglycan_2 PF05510.8 GAM19898.1 - 0.041 12.1 0.1 0.041 12.1 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon EVI2A PF05399.6 GAM19898.1 - 0.042 13.1 0.4 0.044 13.0 0.3 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) TMEM154 PF15102.1 GAM19898.1 - 0.044 13.4 0.3 0.047 13.3 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family Rifin_STEVOR PF02009.11 GAM19898.1 - 0.045 13.3 1.1 0.055 13.1 0.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 GAM19898.1 - 0.054 13.5 2.7 0.066 13.2 1.9 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pox_RNA_Pol_19 PF05320.7 GAM19898.1 - 0.054 13.2 0.3 0.062 13.0 0.2 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FliD_C PF07195.7 GAM19898.1 - 0.057 12.6 0.7 0.069 12.4 0.5 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF2207 PF09972.4 GAM19898.1 - 0.079 11.5 0.1 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex24p PF06398.6 GAM19898.1 - 0.085 11.6 0.1 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CRT-like PF08627.5 GAM19898.1 - 0.12 12.3 0.7 0.15 12.0 0.5 1.2 1 0 0 1 1 1 0 CRT-like Sigma_reg_N PF13800.1 GAM19898.1 - 0.14 12.2 4.5 0.28 11.2 3.2 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal OppC_N PF12911.2 GAM19898.1 - 0.16 11.3 0.8 0.24 10.7 0.6 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF454 PF04304.8 GAM19898.1 - 0.17 11.9 2.0 0.29 11.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF454) TMEM156 PF15106.1 GAM19898.1 - 0.25 10.5 5.8 0.29 10.3 4.0 1.3 1 1 0 1 1 1 0 TMEM156 protein family COX4_pro_2 PF07835.7 GAM19898.1 - 0.94 9.5 6.2 1.8 8.5 4.3 1.5 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Pkinase PF00069.20 GAM19899.1 - 2.8e-48 164.3 0.4 7.6e-48 162.9 0.3 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19899.1 - 2.1e-29 102.4 0.6 6.8e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase ANTH PF07651.11 GAM19899.1 - 3.2e-17 62.1 0.7 3.2e-17 62.1 0.5 2.7 3 0 0 3 3 3 1 ANTH domain Kinase-like PF14531.1 GAM19899.1 - 1.9e-07 30.3 0.0 0.00011 21.2 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 GAM19899.1 - 0.0002 21.2 0.0 0.29 10.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1083 PF06452.6 GAM19900.1 - 2.8e-07 30.5 0.0 3.5e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) Cu-binding_MopE PF11617.3 GAM19900.1 - 0.6 9.9 3.6 1.1 9.0 0.4 2.4 2 0 0 2 2 2 0 Protein metal binding site Pkinase PF00069.20 GAM19901.1 - 3.5e-78 262.3 0.0 6.9e-78 261.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM19901.1 - 3.1e-45 154.2 0.0 5e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 GAM19901.1 - 1.9e-14 52.8 0.0 3.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 GAM19901.1 - 1.2e-05 24.4 0.1 7.9e-05 21.7 0.0 2.4 2 1 0 2 2 2 1 Kinase-like YukC PF10140.4 GAM19901.1 - 0.0006 18.4 4.1 0.00086 17.9 0.1 2.6 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 GAM19901.1 - 0.00075 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM19901.1 - 0.0033 17.2 0.0 0.094 12.4 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.2 GAM19903.1 - 5.8e-31 108.1 0.0 7.1e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM19903.1 - 3.5e-26 92.1 0.3 2e-25 89.7 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM19903.1 - 2.5e-13 50.0 0.0 5.4e-13 48.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM19903.1 - 8.4e-05 22.3 1.5 0.0025 17.5 0.1 2.5 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 GAM19903.1 - 0.0004 19.7 0.0 0.3 10.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAM19903.1 - 0.00049 19.6 0.1 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 GAM19903.1 - 0.00053 19.7 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 GAM19903.1 - 0.00089 18.7 0.9 0.0018 17.7 0.2 2.0 1 1 0 2 2 2 1 Putative esterase FSH1 PF03959.8 GAM19903.1 - 0.0044 16.4 0.3 0.5 9.7 0.0 2.6 1 1 1 2 2 2 1 Serine hydrolase (FSH1) DUF2048 PF09752.4 GAM19903.1 - 0.0084 15.0 0.2 0.046 12.6 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 GAM19903.1 - 0.037 14.2 0.1 0.14 12.3 0.0 1.9 1 1 1 2 2 2 0 Thioesterase domain Glyco_hydro_18 PF00704.23 GAM19904.1 - 9.4e-22 77.9 0.9 4.2e-20 72.4 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Rap_GAP PF02145.10 GAM19905.1 - 3.1e-36 124.5 4.8 8.1e-36 123.1 0.5 2.8 2 0 0 2 2 2 2 Rap/ran-GAP EXS PF03124.9 GAM19906.1 - 1.7e-91 306.8 23.3 2.3e-91 306.3 16.1 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAM19906.1 - 1.7e-43 149.4 4.9 1.7e-43 149.4 3.4 1.7 2 0 0 2 2 2 1 SPX domain RRM_3 PF08777.6 GAM19907.1 - 1.2e-22 79.7 1.8 7.6e-22 77.1 0.1 2.6 2 1 1 3 3 3 1 RNA binding motif La PF05383.12 GAM19907.1 - 2.3e-19 68.9 0.3 4e-19 68.1 0.2 1.4 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 GAM19907.1 - 1.3e-11 44.3 0.0 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM19907.1 - 4.5e-08 32.6 0.0 0.0032 17.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19907.1 - 0.00021 21.0 0.0 0.034 13.9 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VitD-bind_III PF09164.5 GAM19907.1 - 0.0013 18.2 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Vitamin D binding protein, domain III LIM PF00412.17 GAM19908.1 - 4.8e-57 189.8 104.6 3.5e-14 52.5 3.4 10.6 9 1 1 10 10 10 9 LIM domain CH PF00307.26 GAM19908.1 - 9.4e-14 51.3 0.0 3e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM19908.1 - 0.002 17.7 0.0 0.0055 16.3 0.0 1.8 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 GAM19908.1 - 0.004 17.1 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin Inositol_P PF00459.20 GAM19909.1 - 2.6e-44 151.5 0.1 3.3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family LRR_6 PF13516.1 GAM19910.1 - 3.7e-28 94.3 43.6 0.0013 18.5 0.0 13.0 13 0 0 13 13 13 10 Leucine Rich repeat LRR_1 PF00560.28 GAM19910.1 - 1.1e-12 46.1 21.1 1.1 9.5 0.0 11.6 11 1 0 11 11 11 2 Leucine Rich Repeat LRR_4 PF12799.2 GAM19910.1 - 8.4e-11 41.2 39.6 0.095 12.3 0.0 9.2 3 2 7 10 10 10 7 Leucine Rich repeats (2 copies) F-box-like PF12937.2 GAM19910.1 - 3.9e-05 23.2 0.0 0.00018 21.1 0.0 2.2 2 1 0 2 2 2 1 F-box-like LRR_7 PF13504.1 GAM19910.1 - 0.0029 17.5 31.0 0.24 11.7 0.7 10.3 11 0 0 11 11 11 2 Leucine rich repeat Sporozoite_P67 PF05642.6 GAM19910.1 - 0.017 13.0 7.4 0.025 12.4 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_A31 PF05771.6 GAM19910.1 - 0.03 14.1 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Poxvirus A31 protein LRR_8 PF13855.1 GAM19910.1 - 0.16 11.7 40.8 0.33 10.7 0.4 8.5 6 2 7 13 13 13 0 Leucine rich repeat CoA_transf_3 PF02515.12 GAM19911.1 - 6e-61 205.0 0.0 7.7e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Aminotran_1_2 PF00155.16 GAM19912.1 - 2.4e-65 220.8 0.0 2.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM19912.1 - 1.7e-08 33.9 0.0 2.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM19912.1 - 6.6e-07 28.4 0.0 1.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM19912.1 - 6.5e-06 24.6 0.0 1.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 GAM19912.1 - 1.2e-05 24.5 0.0 2.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 GAM19912.1 - 0.045 12.2 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Glyco_hydro_20 PF00728.17 GAM19912.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain Nucleoporin_C PF03177.9 GAM19913.1 - 2.4e-19 69.3 24.1 2.2e-18 66.1 16.8 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Epimerase PF01370.16 GAM19914.1 - 2.9e-12 46.5 0.0 4.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM19914.1 - 5.9e-10 38.5 0.0 1.4e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM19914.1 - 0.00038 19.4 0.1 0.0012 17.7 0.0 1.7 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein SH3_2 PF07653.12 GAM19915.1 - 8e-13 47.6 0.0 1.3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAM19915.1 - 2.9e-09 36.3 0.1 2.9e-09 36.3 0.1 1.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 GAM19915.1 - 1.2e-05 24.6 0.1 1.2e-05 24.6 0.1 1.6 2 0 0 2 2 2 1 SH3 domain PfkB PF00294.19 GAM19916.1 - 3e-61 207.1 0.2 3.8e-61 206.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DEC-1_C PF04626.8 GAM19916.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Dec-1 protein, C terminal region ELFV_dehydrog PF00208.16 GAM19917.1 - 2.9e-56 190.7 0.2 9e-54 182.6 0.0 2.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 GAM19917.1 - 4.5e-45 152.4 0.0 7.3e-45 151.7 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 GAM19917.1 - 0.002 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAM19917.1 - 0.0033 17.6 0.0 0.0088 16.2 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 GAM19917.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_GDH PF05088.7 GAM19917.1 - 0.017 12.5 0.0 0.22 8.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase AlaDh_PNT_C PF01262.16 GAM19917.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.17 GAM19918.1 - 3.8e-38 128.9 0.1 1.8e-17 62.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM19918.1 - 1.4e-21 76.2 0.0 3.4e-08 33.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM19918.1 - 7.9e-19 67.2 0.0 2.1e-07 30.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM19918.1 - 1.1e-05 25.1 0.1 0.17 11.6 0.0 2.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAM19918.1 - 0.0041 16.9 5.7 0.44 10.4 0.0 3.5 4 0 0 4 4 4 2 RNA binding motif SprA-related PF12118.3 GAM19918.1 - 0.027 13.7 25.6 0.041 13.2 17.8 1.2 1 0 0 1 1 1 0 SprA-related family CAF-1_p150 PF11600.3 GAM19918.1 - 1 8.7 17.3 1.8 7.8 12.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ASD2 PF08687.6 GAM19918.1 - 8.2 5.6 15.9 12 5.1 10.6 1.4 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 Citrate_synt PF00285.16 GAM19919.1 - 2.2e-86 289.8 0.0 1.1e-48 165.7 0.0 2.2 1 1 1 2 2 2 2 Citrate synthase Ras PF00071.17 GAM19920.1 - 1.3e-48 164.4 0.6 2.3e-35 121.3 0.1 2.5 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM19920.1 - 4.6e-18 65.8 2.8 2.8e-11 43.9 0.0 3.1 3 1 0 3 3 3 2 Miro-like protein VWA_2 PF13519.1 GAM19920.1 - 6e-13 49.2 0.0 1.5e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Arf PF00025.16 GAM19920.1 - 2.7e-06 26.7 0.4 0.0031 16.7 0.1 3.4 3 1 1 4 4 4 2 ADP-ribosylation factor family DUF1040 PF06288.8 GAM19920.1 - 0.0016 18.6 0.1 0.0056 16.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1040) Sec23_trunk PF04811.10 GAM19920.1 - 0.0024 17.2 0.0 0.036 13.4 0.0 2.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 GAM19920.1 - 0.007 15.9 3.8 0.015 14.8 2.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF2076 PF09849.4 GAM19920.1 - 0.033 14.2 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sec23_BS PF08033.7 GAM19920.1 - 0.057 13.9 0.0 0.23 11.9 0.0 2.0 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain MMR_HSR1 PF01926.18 GAM19920.1 - 0.098 12.6 0.2 3.5 7.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase FNIP PF05725.7 GAM19921.1 - 5.8e-29 99.7 0.0 7e-10 38.7 0.1 3.1 1 1 2 3 3 3 3 FNIP Repeat LRR_5 PF13306.1 GAM19921.1 - 3.3e-06 26.8 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) DUF2475 PF10629.4 GAM19921.1 - 2.9 8.2 5.7 44 4.4 0.3 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF2475) Myb_DNA-bind_6 PF13921.1 GAM19922.1 - 1.4e-52 175.6 29.5 1.2e-15 57.2 0.1 6.3 1 1 5 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM19922.1 - 1.3e-50 169.2 24.5 4.9e-15 55.3 0.3 6.0 5 1 0 5 5 5 5 Myb-like DNA-binding domain Rap1_C PF11626.3 GAM19922.1 - 0.0059 16.4 11.8 0.86 9.5 2.0 4.5 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 GAM19922.1 - 0.069 12.9 2.9 16 5.4 0.1 3.8 3 1 0 3 3 3 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.1 GAM19922.1 - 0.076 13.1 25.8 0.089 12.9 1.5 6.2 3 2 1 5 5 5 0 Myb/SANT-like DNA-binding domain FNIP PF05725.7 GAM19923.1 - 4.6e-96 314.5 49.3 2.5e-12 46.5 0.1 9.2 5 2 4 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM19923.1 - 0.0013 18.6 4.7 8.9 6.3 0.0 6.5 3 2 3 6 6 6 2 Protein of unknown function (DUF1769) SpoU_methylase PF00588.14 GAM19924.1 - 5.1e-26 91.2 0.0 1.2e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family HEAT PF02985.17 GAM19924.1 - 0.021 14.8 0.0 32 4.9 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat Fascin PF06268.8 GAM19925.1 - 6.6e-07 29.4 0.0 8.2e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Fascin domain FGF PF00167.13 GAM19925.1 - 1.8e-06 27.7 0.1 2e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Fibroblast growth factor FRG1 PF06229.7 GAM19925.1 - 0.0067 15.9 0.0 2.3 7.6 0.0 2.0 1 1 1 2 2 2 2 FRG1-like family Met_10 PF02475.11 GAM19925.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Filament PF00038.16 GAM19926.1 - 0.072 12.5 13.9 0.037 13.5 8.2 1.4 1 1 0 1 1 1 0 Intermediate filament protein Ribosomal_60s PF00428.14 GAM19926.1 - 0.24 11.8 8.5 0.65 10.4 0.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein HrpA_pilin PF09589.5 GAM19926.1 - 0.64 10.4 11.1 0.63 10.4 1.8 2.5 2 0 0 2 2 2 0 HrpA pilus formation protein DUF643 PF04867.7 GAM19926.1 - 0.66 10.3 5.3 1.5 9.2 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF643) Glyco_hydro_9 PF00759.14 GAM19927.1 - 7.1e-141 470.1 4.2 8e-141 469.9 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 RLL PF10036.4 GAM19928.1 - 5.1e-43 147.3 6.5 1.2e-42 146.0 4.5 1.5 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein DUF3473 PF11959.3 GAM19928.1 - 0.0077 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) DUF3439 PF11921.3 GAM19928.1 - 0.47 10.2 13.1 1.4 8.6 7.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM19928.1 - 0.47 8.3 12.9 0.71 7.7 9.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 GAM19928.1 - 2.1 6.1 7.7 3.1 5.5 5.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAM19928.1 - 9.9 5.9 20.8 0.28 10.9 9.4 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein PI3_PI4_kinase PF00454.22 GAM19929.1 - 1.3e-44 152.4 0.0 3.2e-44 151.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 GAM19929.1 - 1.3e-10 40.5 0.0 3.4e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 FATC domain ArfGap PF01412.13 GAM19930.1 - 6.2e-37 125.9 0.1 6.2e-37 125.9 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 GAM19930.1 - 4.1e-19 68.7 1.9 1.8e-13 50.6 0.1 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 GAM19930.1 - 1.7e-11 44.3 2.6 1e-05 25.7 0.3 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 GAM19930.1 - 0.0011 19.1 0.2 0.31 11.2 0.0 2.8 2 1 0 2 2 2 2 Pleckstrin homology domain Sugar_tr PF00083.19 GAM19931.1 - 9.6e-40 136.4 27.8 7.3e-39 133.5 19.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM19931.1 - 2.3e-38 131.8 45.3 1.1e-31 109.8 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM19931.1 - 2.2e-09 36.2 17.7 0.00081 17.8 3.9 3.1 1 1 0 3 3 3 3 MFS/sugar transport protein DUF399 PF04187.8 GAM19932.1 - 0.15 11.5 0.1 0.19 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF399 ELO PF01151.13 GAM19933.1 - 2e-68 230.4 20.8 2.5e-68 230.1 14.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_2 PF12796.2 GAM19934.1 - 2e-25 88.9 3.1 1.6e-09 37.9 0.3 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM19934.1 - 2.8e-19 69.0 7.3 6.4e-05 23.3 0.1 6.8 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM19934.1 - 1.2e-18 66.6 12.0 0.00092 19.3 0.1 8.3 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19934.1 - 5.6e-17 60.1 8.3 0.18 12.1 0.0 8.5 7 1 1 8 8 8 6 Ankyrin repeat Ank PF00023.25 GAM19934.1 - 4.5e-14 51.4 8.4 0.84 9.5 0.0 8.4 8 1 1 9 9 9 6 Ankyrin repeat DUF249 PF03158.8 GAM19934.1 - 5e-05 22.9 3.8 1.1 8.7 0.3 3.9 1 1 1 3 3 3 2 Multigene family 530 protein Auxin_canalis PF05703.6 GAM19934.1 - 0.098 12.4 0.1 1.7 8.4 0.1 2.2 1 1 0 1 1 1 0 Auxin canalisation Ras PF00071.17 GAM19935.1 - 1.3e-43 148.2 0.2 1.1e-31 109.4 0.0 2.9 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM19935.1 - 3.9e-11 43.4 0.1 2.4e-06 28.0 0.0 3.7 3 0 0 3 3 3 2 Miro-like protein A2M PF00207.17 GAM19935.1 - 1.1e-08 34.4 0.1 1.1e-07 31.2 0.0 2.8 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Big_5 PF13205.1 GAM19935.1 - 3.5e-08 33.9 7.8 1.9e-06 28.4 0.2 15.1 12 3 2 14 14 14 8 Bacterial Ig-like domain A2M_N PF01835.14 GAM19935.1 - 1.9e-07 31.2 0.1 1.9e-05 24.8 0.0 4.4 4 0 0 4 4 4 1 MG2 domain Arf PF00025.16 GAM19935.1 - 0.0034 16.6 0.0 0.14 11.3 0.0 2.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_2 PF12796.2 GAM19936.1 - 1.1e-09 38.5 0.4 0.0046 17.2 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM19936.1 - 0.0002 21.2 5.2 5.3 7.5 0.0 7.3 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.1 GAM19936.1 - 0.0015 19.0 0.3 6.8 7.3 0.0 5.3 5 1 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM19936.1 - 0.047 13.5 1.0 28 4.7 0.0 4.8 6 1 0 6 6 5 0 Ankyrin repeat BUD22 PF09073.5 GAM19936.1 - 0.1 11.6 11.2 0.14 11.1 7.8 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.8 GAM19936.1 - 0.11 12.4 17.2 0.15 11.9 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 GAM19936.1 - 0.42 9.0 21.3 0.6 8.5 14.8 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 GAM19936.1 - 0.67 9.1 19.9 1 8.5 13.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.3 GAM19936.1 - 0.89 8.5 5.2 1.2 8.0 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.4 GAM19936.1 - 0.94 8.1 26.9 1.4 7.5 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VID27 PF08553.5 GAM19936.1 - 2.3 6.3 18.0 3.3 5.8 12.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 GAM19936.1 - 4 6.7 15.3 6.3 6.0 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 GAM19936.1 - 5 4.9 27.6 7.1 4.4 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 GAM19936.1 - 6.3 6.6 26.8 15 5.4 18.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mis12 PF05859.7 GAM19941.1 - 3.7e-18 65.7 1.8 7.3e-18 64.7 1.3 1.5 1 0 0 1 1 1 1 Mis12 protein AAA_27 PF13514.1 GAM19941.1 - 0.0016 16.2 1.8 0.0019 15.9 1.3 1.1 1 0 0 1 1 1 1 AAA domain BRE1 PF08647.6 GAM19941.1 - 0.011 15.6 1.0 0.011 15.6 0.7 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Enkurin PF13864.1 GAM19941.1 - 0.071 13.3 5.2 0.45 10.7 1.4 2.6 2 0 0 2 2 2 0 Calmodulin-binding PYRIN PF02758.11 GAM19941.1 - 0.1 12.3 3.7 0.22 11.2 1.2 2.5 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain DUF745 PF05335.8 GAM19941.1 - 0.12 11.9 1.3 7.5 6.0 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) V_ATPase_I PF01496.14 GAM19941.1 - 1.3 6.7 6.3 1.6 6.4 4.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 GAM19941.1 - 2.5 7.6 9.6 1.2 8.6 1.5 3.0 2 1 1 3 3 3 0 Septum formation initiator IncA PF04156.9 GAM19941.1 - 4.2 6.9 12.7 20 4.6 8.8 1.9 1 1 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 GAM19941.1 - 6.3 6.9 9.9 0.55 10.2 1.7 2.5 1 1 2 3 3 3 0 Syntaxin-like protein Dioxygenase_C PF00775.16 GAM19943.1 - 0.07 12.3 0.5 0.52 9.5 0.2 2.0 2 0 0 2 2 2 0 Dioxygenase NAC PF01849.13 GAM19945.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 NAC domain LisH PF08513.6 GAM19947.1 - 2.4e-05 23.9 0.1 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 LisH CBF PF03914.12 GAM19948.1 - 9.7e-26 90.1 0.0 9.7e-26 90.1 0.0 2.9 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 GAM19948.1 - 3.9e-23 81.5 3.8 3.9e-23 81.5 2.6 3.1 3 1 0 3 3 3 1 Nucleolar complex-associated protein MCM PF00493.18 GAM19949.1 - 3.3e-136 453.4 0.2 5.3e-136 452.7 0.2 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM19949.1 - 1.9e-24 86.4 1.2 5.3e-24 85.0 0.8 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM19949.1 - 2.6e-06 26.7 0.0 0.0013 17.9 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM19949.1 - 6.4e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM19949.1 - 0.0016 18.0 0.0 0.0052 16.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM19949.1 - 0.015 14.7 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 GAM19949.1 - 0.05 13.9 0.6 0.32 11.4 0.2 2.3 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI PIH1 PF08190.7 GAM19950.1 - 1.2e-18 67.6 20.5 1.7e-10 40.8 0.1 3.2 1 1 2 3 3 3 2 pre-RNA processing PIH1/Nop17 Mucin PF01456.12 GAM19950.1 - 0.077 12.7 22.5 0.15 11.8 15.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein LNS2 PF08235.8 GAM19951.1 - 1.2e-59 200.4 0.0 2.6e-59 199.2 0.0 1.6 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 GAM19951.1 - 6.6e-36 122.3 0.0 1.8e-35 120.9 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region UQ_con PF00179.21 GAM19952.1 - 1.6e-37 128.0 0.0 1.9e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM19952.1 - 0.025 14.3 0.0 0.039 13.6 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RCR PF12273.3 GAM19953.1 - 1e-06 29.3 10.3 1.4e-06 28.9 7.1 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 GAM19953.1 - 1.1e-05 25.6 11.5 1.8e-05 24.9 7.9 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator ODV-E18 PF10717.4 GAM19953.1 - 0.00068 19.0 1.2 0.00095 18.5 0.9 1.2 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 GAM19953.1 - 0.011 16.0 0.7 0.018 15.4 0.5 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF929 PF06053.6 GAM19953.1 - 0.07 12.2 0.9 0.11 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF929) TMEM154 PF15102.1 GAM19953.1 - 0.13 11.9 2.2 0.18 11.5 1.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family DAP10 PF07213.6 GAM19953.1 - 0.18 11.5 1.8 0.29 10.9 1.3 1.4 1 0 0 1 1 1 0 DAP10 membrane protein SKG6 PF08693.5 GAM19953.1 - 0.19 11.0 6.1 0.29 10.4 4.2 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CbiN PF02553.10 GAM19953.1 - 0.19 11.7 0.8 0.36 10.8 0.6 1.5 1 0 0 1 1 1 0 Cobalt transport protein component CbiN Rifin_STEVOR PF02009.11 GAM19953.1 - 0.22 11.1 7.0 0.27 10.8 4.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family Herpes_gE PF02480.11 GAM19953.1 - 1.9 6.6 5.3 0.45 8.7 1.5 1.5 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E SP_C-Propep PF08999.5 GAM19953.1 - 2.3 7.7 6.0 3.2 7.3 4.2 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF3824 PF12868.2 GAM19953.1 - 3.5 8.5 22.6 4.3 8.2 15.7 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AAA_5 PF07728.9 GAM19955.1 - 0.00021 21.0 0.0 0.031 14.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM19955.1 - 0.0024 17.9 0.1 5.6 6.9 0.0 3.9 3 0 0 3 3 3 1 AAA ATPase domain IBR PF01485.16 GAM19955.1 - 0.24 11.2 13.2 2 8.3 2.4 2.9 2 0 0 2 2 2 0 IBR domain AIG1 PF04548.11 GAM19956.1 - 2.5e-07 30.0 0.1 8.7e-07 28.2 0.0 1.9 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAM19956.1 - 6.2e-07 29.3 1.5 1.2e-06 28.4 0.2 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAM19956.1 - 0.0063 17.0 1.5 0.062 13.7 0.2 2.9 2 1 0 2 2 2 1 Miro-like protein V-SNARE PF05008.10 GAM19956.1 - 0.0078 16.3 3.5 0.014 15.5 0.0 3.0 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Dynamin_N PF00350.18 GAM19956.1 - 0.048 13.4 0.2 0.048 13.4 0.1 3.3 3 1 1 4 4 4 0 Dynamin family Laminin_II PF06009.7 GAM19956.1 - 0.62 9.8 6.0 0.63 9.7 1.0 2.8 2 1 0 2 2 2 0 Laminin Domain II CENP-Q PF13094.1 GAM19956.1 - 1.2 9.1 4.7 0.54 10.2 0.1 2.5 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Ank_2 PF12796.2 GAM19958.1 - 1.4e-34 118.2 22.5 3.4e-09 36.9 0.4 7.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM19958.1 - 6.5e-22 77.4 18.4 0.00031 21.1 0.1 9.7 8 3 1 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM19958.1 - 1.7e-21 74.1 21.8 0.88 10.0 0.0 14.5 12 1 3 15 15 15 5 Ankyrin repeat Ank PF00023.25 GAM19958.1 - 2.7e-18 64.7 19.9 0.21 11.4 0.0 13.1 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.1 GAM19958.1 - 7.5e-18 64.1 21.5 0.016 15.4 0.0 12.1 6 4 7 13 13 13 6 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM19958.1 - 3.3e-06 26.7 10.8 0.0053 16.5 0.0 6.0 4 1 1 6 6 6 2 Domain of unknown function (DUF3447) RabGAP-TBC PF00566.13 GAM19959.1 - 6.4e-54 182.6 0.4 1.1e-53 181.9 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SWIM PF04434.12 GAM19960.1 - 5.9e-06 25.6 0.4 1.1e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger AAA_33 PF13671.1 GAM19960.1 - 5.5e-05 23.0 0.6 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Pkinase PF00069.20 GAM19961.1 - 2.2e-63 213.8 0.2 1.9e-42 145.2 0.6 2.3 2 0 0 2 2 2 2 Protein kinase domain PH_3 PF14593.1 GAM19961.1 - 2.5e-38 130.1 0.7 4.6e-38 129.2 0.5 1.4 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 GAM19961.1 - 6.5e-35 120.4 0.0 5.2e-26 91.2 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM19961.1 - 8.9e-07 28.1 0.0 0.01 14.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 GAM19961.1 - 0.027 14.1 0.0 0.085 12.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM19961.1 - 0.049 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM19961.1 - 0.069 12.4 0.2 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Fascin PF06268.8 GAM19961.1 - 0.069 13.2 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Fascin domain Ribosomal_L29e PF01779.12 GAM19962.1 - 5.7e-19 67.7 11.3 5.7e-19 67.7 7.8 2.2 2 0 0 2 2 2 1 Ribosomal L29e protein family DUF966 PF06136.8 GAM19962.1 - 0.16 11.3 3.6 0.17 11.3 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) zf-C2H2 PF00096.21 GAM19963.1 - 1.4e-27 94.3 69.8 1.4e-05 25.1 4.9 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 GAM19963.1 - 2.5e-25 87.4 74.5 1.1e-08 34.9 2.2 10.6 11 0 0 11 11 11 9 Zinc-finger double domain zf-C2H2_4 PF13894.1 GAM19963.1 - 4.3e-25 86.1 63.1 0.00019 21.5 2.9 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM19963.1 - 0.00046 20.2 39.5 0.016 15.3 1.9 8.8 9 1 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM19963.1 - 5.3 7.3 36.4 1.6 9.0 2.4 7.9 9 0 0 9 9 9 0 Zinc-finger of C2H2 type Peptidase_C14 PF00656.17 GAM19965.1 - 2.2e-06 27.5 0.0 2.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DDE_3 PF13358.1 GAM19968.1 - 8.1e-21 74.2 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1948 PF09185.5 GAM19968.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Peptidase_C14 PF00656.17 GAM19969.1 - 4.9e-06 26.4 0.0 8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Caspase domain EF-hand_4 PF12763.2 GAM19970.1 - 4.2e-22 77.8 0.0 1.4e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Dynamin_N PF00350.18 GAM19970.1 - 3.3e-10 40.0 0.0 5.1e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EF-hand_1 PF00036.27 GAM19970.1 - 1.2e-06 27.3 0.1 4.3e-06 25.6 0.0 2.0 1 0 0 1 1 1 1 EF hand MMR_HSR1 PF01926.18 GAM19970.1 - 0.00013 21.8 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 GAM19970.1 - 0.0012 18.9 0.0 0.0034 17.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair GTP_EFTU PF00009.22 GAM19970.1 - 0.0042 16.5 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.1 GAM19970.1 - 0.0058 16.2 0.4 0.018 14.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM19970.1 - 0.006 15.8 0.0 0.015 14.5 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 GAM19970.1 - 0.0077 16.0 0.1 0.037 13.9 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain Isochorismatase PF00857.15 GAM19970.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family Ribosom_S12_S23 PF00164.20 GAM19971.1 - 3.4e-38 129.7 1.0 4e-38 129.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peptidase_M28 PF04389.12 GAM19972.1 - 5e-18 65.4 0.0 1.3e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 VWA_2 PF13519.1 GAM19973.1 - 8.8e-05 22.6 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM19973.1 - 0.0051 16.5 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Autophagy_N PF03986.8 GAM19974.1 - 2.2e-45 154.0 1.0 2.9e-45 153.6 0.7 1.1 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Yippee-Mis18 PF03226.9 GAM19975.1 - 0.00037 20.4 3.0 0.00059 19.8 2.1 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.13 GAM19975.1 - 0.0078 15.8 0.3 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 SelR domain Ten1_2 PF15490.1 GAM19975.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit DUF647 PF04884.9 GAM19976.1 - 2.5e-97 324.9 0.7 4.1e-97 324.2 0.5 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PA14 PF07691.7 GAM19976.1 - 2.2e-16 59.8 0.2 4.7e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM19976.1 - 0.0093 15.7 7.1 0.0093 15.7 4.9 14.2 16 1 0 16 16 16 4 Dictyostelium (slime mold) repeat OppC_N PF12911.2 GAM19976.1 - 0.06 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PA14 PF07691.7 GAM19977.1 - 1e-17 64.1 0.2 1.8e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM19977.1 - 1.2e-07 31.4 26.2 1.8e-05 24.4 4.7 15.3 14 2 1 15 15 15 5 Dictyostelium (slime mold) repeat OppC_N PF12911.2 GAM19977.1 - 0.14 11.5 0.1 0.41 10.0 0.1 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PA14 PF07691.7 GAM19978.1 - 2.7e-08 33.5 0.2 1.9e-07 30.8 0.2 2.1 1 1 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM19978.1 - 4.5e-06 26.3 21.6 0.00019 21.1 4.3 12.8 14 1 0 14 14 14 4 Dictyostelium (slime mold) repeat Mnd1 PF03962.10 GAM19979.1 - 0.14 11.8 1.1 3.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Mnd1 family Rad21_Rec8_N PF04825.8 GAM19980.1 - 5.9e-35 119.5 0.0 1.6e-34 118.1 0.0 1.8 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 GAM19980.1 - 5.2e-12 44.7 0.0 2.2e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 GAM19980.1 - 1.2e-05 25.0 1.4 4e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 ScpA/B protein Ras PF00071.17 GAM19981.1 - 2.1e-62 209.2 0.9 2.6e-62 208.9 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19981.1 - 8.6e-19 68.1 0.1 1.4e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19981.1 - 1.4e-15 56.9 0.2 1.7e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM19981.1 - 2.9e-07 30.4 0.3 6.1e-07 29.3 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM19981.1 - 3.9e-05 23.1 0.1 0.00041 19.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM19981.1 - 4.6e-05 22.7 0.1 9e-05 21.7 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 GAM19981.1 - 0.00099 18.8 0.8 0.18 11.4 0.0 2.1 1 1 1 2 2 2 2 Archaeal ATPase AAA_22 PF13401.1 GAM19981.1 - 0.0051 16.9 0.2 0.14 12.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM19981.1 - 0.01 15.8 0.1 0.075 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 GAM19981.1 - 0.012 14.8 0.0 0.017 14.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 GAM19981.1 - 0.016 15.4 0.1 0.64 10.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM19981.1 - 0.027 14.3 0.3 0.18 11.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain Septin PF00735.13 GAM19981.1 - 0.036 13.0 0.4 0.072 12.0 0.0 1.6 2 0 0 2 2 2 0 Septin G6PD_C PF02781.11 GAM19981.1 - 0.041 12.7 0.1 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain KAP_NTPase PF07693.9 GAM19981.1 - 0.043 12.8 0.0 0.054 12.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain FeoB_N PF02421.13 GAM19981.1 - 0.048 12.9 0.2 0.52 9.5 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4471 PF14740.1 GAM19981.1 - 0.073 12.2 0.3 0.1 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) YtzH PF14165.1 GAM19981.1 - 0.11 12.7 0.1 0.69 10.1 0.1 2.0 2 0 0 2 2 2 0 YtzH-like protein MobB PF03205.9 GAM19981.1 - 0.13 12.0 0.9 0.49 10.0 0.4 2.3 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 GAM19981.1 - 0.26 11.5 1.8 0.89 9.8 1.3 1.9 1 1 0 1 1 1 0 ABC transporter Histone PF00125.19 GAM19982.1 - 1.6e-13 50.5 0.2 2.2e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM19982.1 - 4.5e-05 23.5 0.2 5.7e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 GAM19982.1 - 4.8e-05 23.2 0.0 6.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 GAM19982.1 - 0.00051 20.0 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAM19982.1 - 0.00085 19.0 0.1 0.0033 17.1 0.0 1.8 1 1 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 GAM19982.1 - 0.0078 15.4 0.0 0.0084 15.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 GAM19982.1 - 0.054 13.3 0.1 0.11 12.2 0.1 1.5 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 GAM19982.1 - 0.14 11.8 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit tRNA_anti-codon PF01336.20 GAM19983.1 - 0.018 14.9 0.1 0.46 10.3 0.0 2.8 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Pkinase_Tyr PF07714.12 GAM19984.1 - 3.7e-53 180.2 0.0 6.5e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM19984.1 - 1.2e-45 155.7 0.0 3.4e-45 154.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain PH PF00169.24 GAM19984.1 - 5.8e-08 32.8 3.5 9.6e-08 32.1 0.5 2.7 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM19984.1 - 8.8e-05 22.7 0.0 0.00046 20.4 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.9 GAM19984.1 - 0.15 11.1 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Frizzled PF01534.12 GAM19985.1 - 0.033 12.9 0.0 0.035 12.9 0.0 1.0 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region FAM176 PF14851.1 GAM19985.1 - 0.059 13.0 0.0 0.063 12.9 0.0 1.2 1 1 0 1 1 1 0 FAM176 family Apocytochr_F_C PF01333.14 GAM19985.1 - 0.1 12.4 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Apocytochrome F, C-terminal Flavoprotein PF02441.14 GAM19988.1 - 6.4e-45 151.9 0.0 9.1e-45 151.4 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein EF-hand_1 PF00036.27 GAM19989.1 - 6.1e-17 59.5 16.4 7.1e-06 24.9 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 GAM19989.1 - 1.5e-16 60.2 19.7 9.9e-08 32.0 2.5 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 GAM19989.1 - 6.6e-15 53.5 10.8 0.0015 18.2 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAM19989.1 - 5.9e-13 47.5 16.9 0.00013 21.1 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 GAM19989.1 - 8.9e-13 47.6 11.5 5.9e-06 25.8 0.8 4.3 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM19989.1 - 0.0012 18.8 1.1 2.6 8.1 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 GAM19989.1 - 0.11 12.5 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 EF hand FNIP PF05725.7 GAM19990.1 - 1.9e-67 222.9 31.8 2.8e-13 49.5 0.1 8.7 6 1 3 9 9 9 9 FNIP Repeat Beta-lactamase PF00144.19 GAM19991.1 - 0.027 13.5 0.2 0.089 11.7 0.1 1.7 1 1 1 2 2 2 0 Beta-lactamase DUF3340 PF11818.3 GAM19992.1 - 0.054 13.4 3.3 0.074 13.0 2.3 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) ArsC PF03960.10 GAM19992.1 - 0.085 12.9 0.5 0.25 11.4 0.4 1.8 1 1 0 1 1 1 0 ArsC family GCIP PF13324.1 GAM19993.1 - 6.4e-22 78.0 2.8 4.3e-20 72.0 1.9 2.1 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting IpaD PF06511.6 GAM19993.1 - 0.017 14.1 0.5 0.032 13.2 0.3 1.4 1 1 0 1 1 1 0 Invasion plasmid antigen IpaD DUF4484 PF14831.1 GAM19993.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Ribosomal_60s PF00428.14 GAM19993.1 - 0.92 9.9 5.7 1.7 9.0 3.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Gelsolin PF00626.17 GAM19994.1 - 3.1e-27 94.0 0.0 4.5e-07 29.4 0.0 5.6 5 0 0 5 5 5 5 Gelsolin repeat Bowman-Birk_leg PF00228.15 GAM19994.1 - 0.13 12.1 0.5 0.24 11.2 0.4 1.4 1 0 0 1 1 1 0 Bowman-Birk serine protease inhibitor family Kinetochor_Ybp2 PF08568.5 GAM19995.1 - 8.7e-24 83.7 3.9 3.6e-14 51.9 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Ras PF00071.17 GAM19996.1 - 2e-53 180.0 0.0 3.4e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM19996.1 - 1.4e-21 77.2 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM19996.1 - 7e-08 31.9 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM19996.1 - 8.4e-07 28.6 0.3 3.1e-05 23.5 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM19996.1 - 0.00018 21.4 0.0 0.00032 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM19996.1 - 0.0011 18.5 0.7 0.01 15.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.15 GAM19996.1 - 0.0032 16.1 1.8 0.39 9.3 0.1 3.0 1 1 1 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.1 GAM19996.1 - 0.0041 16.7 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 GAM19996.1 - 0.011 14.8 0.7 0.014 14.5 0.0 1.5 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 GAM19996.1 - 0.041 13.0 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 CbiA PF01656.18 GAM19996.1 - 0.058 12.7 0.4 0.24 10.7 0.1 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 GAM19996.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM19996.1 - 0.11 12.5 0.7 0.61 10.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAM19996.1 - 0.14 12.0 0.1 0.65 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain PI3Ka PF00613.15 GAM19998.1 - 1.6e-52 177.3 0.0 3.4e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM19998.1 - 1.4e-24 86.8 0.3 4.6e-24 85.2 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM19998.1 - 3.6e-15 55.9 0.0 9.1e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 GAM19998.1 - 5e-14 52.1 0.6 2.7e-08 33.6 0.0 2.7 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain BacA PF02673.13 GAM19998.1 - 0.063 12.4 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacitracin resistance protein BacA S10_plectin PF03501.10 GAM19999.1 - 9.2e-38 128.0 0.1 1.1e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Amino_oxidase PF01593.19 GAM20000.1 - 2.3e-17 63.2 0.0 3.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM20000.1 - 5.4e-09 35.9 0.0 1.8e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 GAM20000.1 - 0.0016 18.2 0.0 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 GAM20000.1 - 0.049 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HEAT PF02985.17 GAM20001.1 - 1.1e-08 34.3 0.1 0.034 14.2 0.0 4.6 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 GAM20001.1 - 5.4e-07 29.0 0.0 9.3e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20001.1 - 1.1e-06 27.9 0.0 2.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 GAM20001.1 - 0.0021 18.3 0.0 0.039 14.2 0.0 2.6 2 1 0 2 2 2 1 HEAT repeats Kinase-like PF14531.1 GAM20001.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Adaptin_N PF01602.15 GAM20001.1 - 0.014 13.7 1.0 1.9 6.6 0.1 2.2 1 1 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 GAM20001.1 - 0.017 15.6 0.0 11 6.6 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM20001.1 - 0.074 13.4 0.1 23 5.4 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region CD99L2 PF12301.3 GAM20001.1 - 5.5 6.6 17.8 0.054 13.1 6.4 2.0 2 0 0 2 2 2 0 CD99 antigen like protein 2 ESCRT-II PF05871.7 GAM20002.1 - 2.5e-47 160.2 4.1 3.6e-47 159.7 2.8 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Nuf2 PF03800.9 GAM20002.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Nuf2 family MFS_1 PF07690.11 GAM20003.1 - 1.9e-22 79.4 4.7 3.2e-21 75.4 2.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 GAM20003.1 - 3.4e-10 39.2 18.8 2.9e-05 23.0 5.8 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_1_like PF12832.2 GAM20003.1 - 1.7e-07 30.9 2.3 1.7e-07 30.9 1.6 3.4 3 0 0 3 3 3 2 MFS_1 like family Ubiq_cyt_C_chap PF03981.7 GAM20004.1 - 6.4e-34 116.8 0.3 9.5e-34 116.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Paramyxo_C PF01692.13 GAM20004.1 - 0.0086 15.7 0.4 0.015 14.9 0.3 1.3 1 0 0 1 1 1 1 Paramyxovirus non-structural protein c SHQ1 PF04925.10 GAM20006.1 - 3.1e-60 202.8 3.3 5.3e-60 202.1 2.3 1.3 1 0 0 1 1 1 1 SHQ1 protein PKD PF00801.15 GAM20007.1 - 0.00064 19.4 6.9 0.031 14.0 0.1 4.4 4 0 0 4 4 4 1 PKD domain hEGF PF12661.2 GAM20007.1 - 1.4 9.1 16.0 0.43 10.7 2.8 3.5 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.19 GAM20007.1 - 5.9 6.8 23.5 47 4.0 10.3 2.8 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) COX17 PF05051.8 GAM20008.1 - 1.3e-22 79.4 7.9 1.6e-22 79.2 5.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CoA_trans PF01144.18 GAM20009.1 - 8.3e-115 381.4 2.1 1.5e-74 249.8 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 GAM20009.1 - 0.0012 18.4 0.2 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain TRP PF06011.7 GAM20010.1 - 2.8e-10 39.3 31.5 6.4e-09 34.8 22.0 2.7 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel EGF_2 PF07974.8 GAM20010.1 - 0.00036 20.6 57.8 0.036 14.2 9.3 4.1 4 0 0 4 4 4 3 EGF-like domain PQQ_3 PF13570.1 GAM20010.1 - 0.084 13.1 0.1 0.34 11.2 0.0 2.1 1 0 0 1 1 1 0 PQQ-like domain Baculo_PEP_C PF04513.7 GAM20013.1 - 0.0051 16.6 2.0 0.046 13.5 1.2 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Ank_2 PF12796.2 GAM20014.1 - 4.7e-11 42.8 4.0 1.3e-06 28.5 0.8 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20014.1 - 3.3e-10 39.2 4.1 0.6 10.5 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM20014.1 - 4.6e-08 33.3 3.2 0.088 13.3 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20014.1 - 1.3e-07 31.6 4.7 0.019 15.1 0.0 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM20014.1 - 0.0037 17.0 5.3 3.5 7.6 0.0 4.6 4 1 1 5 5 5 1 Ankyrin repeat Viral_helicase1 PF01443.13 GAM20014.1 - 0.04 13.4 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SMK-1 PF04802.10 GAM20015.1 - 6.8e-65 218.2 11.3 6.8e-65 218.2 7.8 2.2 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 MGAT2 PF05060.9 GAM20016.1 - 7.6e-61 205.9 13.7 1.7e-58 198.2 9.5 2.1 1 1 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) DENN PF02141.16 GAM20017.1 - 5.6e-27 94.6 8.1 3e-25 89.0 2.3 2.5 1 1 0 2 2 2 2 DENN (AEX-3) domain Avl9 PF09794.4 GAM20017.1 - 7.5e-07 27.9 2.3 9.5e-07 27.6 0.5 1.9 2 0 0 2 2 2 1 Transport protein Avl9 uDENN PF03456.13 GAM20017.1 - 1e-06 28.5 0.8 1.4e-05 24.9 0.5 2.5 1 1 0 1 1 1 1 uDENN domain SPA PF08616.5 GAM20017.1 - 2.3e-05 24.0 2.1 6.1e-05 22.6 1.4 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis dDENN PF03455.14 GAM20017.1 - 0.018 15.1 1.4 0.049 13.7 1.0 1.8 1 0 0 1 1 1 0 dDENN domain Sua5_yciO_yrdC PF01300.13 GAM20018.1 - 3.5e-46 156.6 0.0 6.1e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 GAM20018.1 - 8.5e-12 45.2 0.0 2.8e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Kelch_6 PF13964.1 GAM20019.1 - 1.6e-08 34.3 0.6 0.00045 20.2 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM20019.1 - 0.00024 20.7 2.9 0.55 10.0 0.0 3.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM20019.1 - 0.0049 16.5 0.9 0.53 10.1 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 GAM20019.1 - 0.0055 16.2 5.9 1 8.9 0.0 4.3 4 1 0 4 4 4 2 Kelch motif GATase_5 PF13507.1 GAM20022.1 - 2.1e-95 318.5 0.0 3.7e-95 317.7 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 GAM20022.1 - 9.1e-34 116.6 2.0 1.2e-18 67.5 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAM20022.1 - 8.1e-18 64.4 2.9 5.7e-15 55.3 0.0 3.7 3 0 0 3 3 3 2 AIR synthase related protein, N-terminal domain Pkinase PF00069.20 GAM20023.1 - 2.5e-57 193.9 0.0 4.1e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20023.1 - 1e-56 191.8 0.0 1.6e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.14 GAM20023.1 - 1.6e-39 135.5 0.0 2.8e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM20023.1 - 2.8e-21 75.5 0.3 6.7e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Kdo PF06293.9 GAM20023.1 - 0.024 13.6 0.1 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAM20023.1 - 0.028 13.9 0.1 0.083 12.4 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 GAM20023.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM20023.1 - 0.047 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like NUC153 PF08159.7 GAM20024.1 - 4.2e-08 32.6 1.9 4.2e-08 32.6 1.3 4.8 4 0 0 4 4 4 3 NUC153 domain TPR_12 PF13424.1 GAM20025.1 - 1.4e-09 37.7 5.7 0.00066 19.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM20025.1 - 1.9e-05 24.1 10.9 0.0049 16.4 1.7 3.6 1 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 GAM20025.1 - 0.0018 17.9 0.7 5.5 7.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20025.1 - 0.002 17.8 5.3 0.46 10.5 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Glu_syn_central PF04898.9 GAM20025.1 - 0.017 14.4 1.3 0.034 13.3 0.9 1.5 1 0 0 1 1 1 0 Glutamate synthase central domain TPR_1 PF00515.23 GAM20025.1 - 0.037 13.6 4.9 3.1 7.5 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM20025.1 - 0.085 12.8 0.6 1.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20025.1 - 3.5 7.6 7.5 26 4.9 1.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Laminin_EGF PF00053.19 GAM20026.1 - 0.0044 16.9 17.9 0.0083 16.0 6.5 2.4 1 1 1 2 2 2 1 Laminin EGF-like (Domains III and V) hEGF PF12661.2 GAM20026.1 - 0.01 15.8 22.2 0.066 13.3 1.2 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF Integrin_b_cyt PF08725.6 GAM20026.1 - 0.027 13.8 0.1 0.078 12.3 0.0 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Dynein_heavy PF03028.10 GAM20026.1 - 0.086 10.8 0.2 0.13 10.2 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor EGF_2 PF07974.8 GAM20026.1 - 0.19 11.9 19.9 1.1 9.5 3.8 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 GAM20027.1 - 0.013 15.4 17.9 0.052 13.4 6.9 2.6 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 GAM20027.1 - 1.2 9.4 26.1 0.25 11.5 3.8 4.1 3 0 0 3 3 3 0 Human growth factor-like EGF DUF4175 PF13779.1 GAM20027.1 - 4.9 4.7 1.2 8.8 3.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) GRAM PF02893.15 GAM20028.1 - 9.5e-38 127.5 4.3 4.2e-15 55.0 0.0 5.2 5 0 0 5 5 5 4 GRAM domain Glyco_transf_28 PF03033.15 GAM20028.1 - 2.8e-21 75.7 0.0 5.2e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 GAM20028.1 - 1.6e-13 50.7 4.9 1.1e-11 44.7 0.1 3.8 4 0 0 4 4 3 1 PH domain FYVE PF01363.16 GAM20028.1 - 3.3e-12 46.0 4.6 7.1e-12 45.0 3.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger UDPGT PF00201.13 GAM20028.1 - 8.8e-09 34.4 0.0 2.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase bPH_3 PF14470.1 GAM20028.1 - 0.0016 18.6 6.5 0.015 15.5 0.0 4.3 4 1 0 4 4 4 1 Bacterial PH domain PH_BEACH PF14844.1 GAM20028.1 - 0.0051 16.6 2.3 3.4 7.5 0.1 4.2 4 0 0 4 4 4 1 PH domain associated with Beige/BEACH FYVE_2 PF02318.11 GAM20028.1 - 0.0098 15.7 4.4 0.029 14.2 3.0 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Vps36_ESCRT-II PF11605.3 GAM20028.1 - 0.016 14.9 0.2 41 4.0 0.0 4.2 4 0 0 4 4 4 0 Vacuolar protein sorting protein 36 Vps36 Glyco_tran_28_C PF04101.11 GAM20028.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain SspB PF04386.8 GAM20028.1 - 0.055 13.0 1.5 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 Stringent starvation protein B zf-C2HC5 PF06221.8 GAM20028.1 - 0.2 11.4 5.7 0.034 13.9 0.7 2.0 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-B_box PF00643.19 GAM20028.1 - 0.26 11.2 4.5 0.81 9.6 3.1 1.9 1 0 0 1 1 1 0 B-box zinc finger C1_4 PF07975.7 GAM20028.1 - 0.35 10.9 6.5 1.1 9.3 4.5 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain zf-RING_5 PF14634.1 GAM20028.1 - 1.3 8.7 7.3 3.2 7.5 5.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-AN1 PF01428.11 GAM20028.1 - 7.8 6.4 10.1 87 3.1 7.1 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger GNT-I PF03071.10 GAM20029.1 - 1.2e-73 248.1 6.8 2.6e-64 217.3 1.4 2.0 1 1 1 2 2 2 2 GNT-I family CTP_transf_2 PF01467.21 GAM20030.1 - 1.1e-07 32.0 0.2 1.4e-06 28.4 0.0 2.4 2 1 0 2 2 2 1 Cytidylyltransferase Citrate_synt PF00285.16 GAM20031.1 - 3e-114 381.4 0.0 3.4e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Ank_2 PF12796.2 GAM20032.1 - 1.9e-67 223.6 26.5 1e-11 44.9 0.2 5.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20032.1 - 4.1e-36 122.2 18.7 0.0046 17.1 0.0 12.7 2 1 11 13 13 13 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20032.1 - 4.3e-34 116.2 17.9 1.1e-05 25.7 0.1 9.4 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20032.1 - 4.2e-29 97.6 19.4 0.14 12.4 0.0 13.2 7 3 6 13 13 13 9 Ankyrin repeat Ank PF00023.25 GAM20032.1 - 7.6e-27 91.7 17.7 0.056 13.2 0.0 12.7 10 2 3 13 13 13 7 Ankyrin repeat Rbsn PF11464.3 GAM20032.1 - 0.0011 18.4 0.1 1.8 8.1 0.2 5.4 8 0 0 8 8 8 1 Rabenosyn Rab binding domain TPP_enzyme_C PF02775.16 GAM20032.1 - 0.063 12.8 0.1 1.6 8.2 0.0 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cas_Csy1 PF09611.5 GAM20032.1 - 0.14 11.0 0.1 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy1) Brix PF04427.13 GAM20033.1 - 2.8e-50 170.6 0.3 3.8e-50 170.1 0.2 1.2 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 GAM20033.1 - 0.063 13.2 0.0 0.25 11.2 0.0 2.1 2 1 0 2 2 2 0 Bromodomain Rap_GAP PF02145.10 GAM20034.1 - 2.8e-25 88.7 0.1 5e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP RhoGAP PF00620.22 GAM20035.1 - 1.8e-29 102.3 0.7 7.9e-28 96.9 0.0 2.8 2 0 0 2 2 2 2 RhoGAP domain DUF4557 PF15101.1 GAM20037.1 - 0.096 12.5 5.3 0.14 11.9 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Helicase_RecD PF05127.9 GAM20037.1 - 0.17 11.5 1.2 0.28 10.8 0.9 1.3 1 0 0 1 1 1 0 Helicase HGTP_anticodon2 PF12745.2 GAM20037.1 - 0.83 8.7 10.0 0.53 9.3 5.8 1.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Flg_bb_rod PF00460.15 GAM20037.1 - 0.92 9.2 0.1 0.92 9.2 0.1 3.2 2 1 0 2 2 2 0 Flagella basal body rod protein FAM176 PF14851.1 GAM20037.1 - 1.2 8.7 5.2 2 8.0 3.6 1.3 1 0 0 1 1 1 0 FAM176 family PHD_3 PF13922.1 GAM20037.1 - 5 7.4 10.1 11 6.3 7.0 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Endonuc_Holl PF10107.4 GAM20037.1 - 7.6 6.2 8.4 13 5.4 5.8 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Gag_spuma PF03276.9 GAM20037.1 - 8.8 4.5 13.8 12 4.1 9.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Fork_head PF00250.13 GAM20039.1 - 0.0038 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Fork head domain RVT_1 PF00078.22 GAM20040.1 - 6.6e-25 87.7 0.0 9.8e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ammonium_transp PF00909.16 GAM20042.1 - 2.1e-111 372.2 23.4 2.4e-111 372.0 16.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ribonuc_L-PSP PF01042.16 GAM20045.1 - 1.5e-37 128.0 0.1 1.8e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Inhibitor_I10 PF12559.3 GAM20045.1 - 0.034 14.4 0.8 0.06 13.6 0.1 1.7 2 0 0 2 2 2 0 Serine endopeptidase inhibitors UQ_con PF00179.21 GAM20046.1 - 1.1e-21 76.6 1.5 1.2e-20 73.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme FCP1_C PF09309.5 GAM20046.1 - 0.021 14.1 5.4 0.039 13.2 3.7 1.4 1 0 0 1 1 1 0 FCP1, C-terminal FRQ PF09421.5 GAM20046.1 - 0.87 7.2 6.8 1.2 6.8 4.7 1.0 1 0 0 1 1 1 0 Frequency clock protein CMV_1a PF12467.3 GAM20046.1 - 2.2 8.6 9.7 9.7 6.5 5.8 2.1 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family DUF2967 PF11179.3 GAM20046.1 - 3.2 7.1 13.3 4.4 6.7 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4175 PF13779.1 GAM20046.1 - 3.4 5.2 14.4 4.5 4.8 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) INT_SG_DDX_CT_C PF15300.1 GAM20047.1 - 0.00018 20.8 0.3 0.00033 20.0 0.2 1.4 1 0 0 1 1 1 1 INTS6/SAGE1/DDX26B/CT45 C-terminus CIMR PF00878.13 GAM20048.1 - 3.4e-10 39.8 2.3 5e-08 32.8 0.7 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 GAM20048.1 - 5.8e-09 35.5 0.5 6.6e-09 35.4 0.3 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 GAM20048.1 - 0.00082 18.6 2.2 0.0021 17.3 1.5 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 MutS_V PF00488.16 GAM20051.1 - 1.7e-84 282.9 0.0 2.7e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM20051.1 - 5e-41 140.7 0.1 1e-40 139.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAM20051.1 - 6.4e-29 100.2 0.1 1.5e-28 99.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAM20051.1 - 6.4e-16 58.6 0.0 2.1e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 GAM20051.1 - 9.7e-10 38.4 3.4 9.7e-10 38.4 2.4 2.0 2 0 0 2 2 2 1 MutS family domain IV PRELI PF04707.9 GAM20052.1 - 2.1e-26 92.3 0.7 2.8e-26 91.9 0.5 1.1 1 0 0 1 1 1 1 PRELI-like family DUF3446 PF11928.3 GAM20053.1 - 0.002 18.2 2.5 0.002 18.2 1.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) DUF3735 PF12537.3 GAM20053.1 - 0.005 16.8 0.1 0.0091 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Secretin_N_2 PF07655.8 GAM20053.1 - 0.0073 16.6 5.2 0.0073 16.6 3.6 1.4 2 0 0 2 2 2 1 Secretin N-terminal domain Nse4_C PF08743.5 GAM20053.1 - 0.061 13.3 0.2 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 Nse4 C-terminal FAA_hydrolase_N PF09298.6 GAM20053.1 - 0.11 12.4 1.5 0.14 12.1 0.6 1.5 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal OHCU_decarbox PF09349.5 GAM20053.1 - 0.16 12.2 1.2 0.26 11.5 0.9 1.4 1 1 0 1 1 1 0 OHCU decarboxylase GET2 PF08690.5 GAM20053.1 - 0.93 8.6 7.6 5.1 6.2 5.4 1.8 1 1 1 2 2 2 0 GET complex subunit GET2 Ribosomal_S3_C PF00189.15 GAM20054.1 - 3.7e-16 59.0 0.1 7e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 GAM20054.1 - 2.6e-11 42.9 0.0 4.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 KH domain HMG_box PF00505.14 GAM20057.1 - 1.4e-17 63.6 2.1 4.7e-17 62.0 1.4 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM20057.1 - 2e-11 44.1 1.7 6.6e-11 42.4 1.2 1.9 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 GAM20057.1 - 0.0044 17.2 2.7 0.0044 17.2 1.9 2.1 2 0 0 2 2 2 1 YABBY protein CDC45 PF02724.9 GAM20057.1 - 0.027 12.4 13.0 0.033 12.2 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.8 GAM20057.1 - 0.19 9.8 6.5 0.2 9.7 4.5 1.1 1 0 0 1 1 1 0 Menin Sporozoite_P67 PF05642.6 GAM20057.1 - 0.69 7.7 10.5 1 7.1 7.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.8 GAM20057.1 - 0.83 9.2 26.7 1.2 8.7 18.2 1.5 1 1 0 1 1 1 0 YL1 nuclear protein DUF572 PF04502.8 GAM20057.1 - 0.94 8.6 20.3 1.1 8.4 14.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Podoplanin PF05808.6 GAM20057.1 - 2.1 7.8 8.3 3.4 7.1 5.7 1.3 1 0 0 1 1 1 0 Podoplanin DUF3409 PF11889.3 GAM20057.1 - 7.6 6.3 9.1 1.5 8.5 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3409) MAT_Alpha1 PF04769.7 GAM20057.1 - 8.1 5.7 8.9 0.36 10.1 2.0 1.7 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 SAP PF02037.22 GAM20058.1 - 5.9e-11 41.5 0.9 1.3e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 SAP domain Pkinase PF00069.20 GAM20059.1 - 5.9e-49 166.5 0.0 1.3e-48 165.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20059.1 - 7.7e-27 93.9 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 GAM20059.1 - 9.6e-24 83.1 8.4 6.1e-16 58.1 0.1 3.9 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.1 GAM20059.1 - 3.3e-07 29.5 0.3 7e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM20059.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TFIIA PF03153.8 GAM20059.1 - 0.43 10.4 14.1 0.55 10.0 9.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Protamine_P2 PF00841.14 GAM20059.1 - 1.6 9.3 5.3 4.3 7.9 3.7 1.7 1 0 0 1 1 1 0 Sperm histone P2 Pkinase PF00069.20 GAM20060.1 - 1.7e-13 50.3 0.3 3.2e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20060.1 - 9.1e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase M20_dimer PF07687.9 GAM20060.1 - 0.035 13.8 0.3 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain DUF605 PF04652.11 GAM20060.1 - 0.17 11.2 16.5 0.18 11.1 11.4 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 GAM20060.1 - 1.3 8.8 15.6 1.4 8.7 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Steroid_dh PF02544.11 GAM20061.1 - 1.9e-23 82.9 3.9 2.6e-23 82.4 2.1 1.8 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 GAM20061.1 - 0.6 10.2 5.8 0.12 12.5 0.7 2.4 2 2 1 3 3 3 0 Phospholipid methyltransferase TPR_16 PF13432.1 GAM20062.1 - 6.7e-09 36.1 4.0 0.0016 19.0 0.2 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20062.1 - 2.5e-08 33.8 2.4 0.087 13.5 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM20062.1 - 3.4e-06 26.6 2.9 0.0014 18.2 0.5 3.5 1 1 2 3 3 3 3 TPR repeat TPR_12 PF13424.1 GAM20062.1 - 2e-05 24.3 2.6 0.16 11.9 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM20062.1 - 2.2e-05 24.6 0.3 0.34 11.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20062.1 - 3.5e-05 23.3 2.7 1.5 8.9 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20062.1 - 3.7e-05 23.5 1.3 0.022 14.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM20062.1 - 5.7e-05 22.8 2.5 0.0064 16.3 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20062.1 - 5.7e-05 22.5 5.6 0.006 16.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20062.1 - 0.00014 22.1 3.9 0.064 13.5 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20062.1 - 0.00037 20.0 0.1 1.4 8.8 0.1 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAM20062.1 - 0.0011 18.0 2.5 0.0042 16.1 0.8 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20062.1 - 0.0095 15.6 0.2 13 5.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM20062.1 - 0.024 14.7 2.8 0.15 12.2 0.5 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 UvrD-helicase PF00580.16 GAM20062.1 - 0.038 13.3 0.3 0.06 12.6 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain TPR_20 PF14561.1 GAM20062.1 - 0.077 13.1 2.9 0.13 12.3 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.18 GAM20064.1 - 2.2e-07 30.8 0.5 9.4e-06 25.5 0.1 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase GBP PF02263.14 GAM20064.1 - 2.1e-06 27.0 0.0 3.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Methyltransf_23 PF13489.1 GAM20066.1 - 1.5e-09 37.7 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM20066.1 - 1.2e-07 32.1 0.0 3.7e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.7 GAM20066.1 - 2.1e-07 30.5 0.0 2.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 GAM20066.1 - 6.9e-06 26.6 0.0 2.1e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM20066.1 - 3.1e-05 23.9 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM20066.1 - 5.1e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM20066.1 - 0.00016 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM20066.1 - 0.00056 19.0 0.0 0.00099 18.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAM20066.1 - 0.003 17.1 0.0 0.01 15.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 GAM20066.1 - 0.008 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) DOT1 PF08123.8 GAM20066.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.15 GAM20066.1 - 0.032 13.2 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3419 PF11899.3 GAM20066.1 - 0.067 11.8 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) DUF1162 PF06650.7 GAM20068.1 - 2e-38 132.2 6.9 3e-38 131.6 1.8 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM20068.1 - 2.5e-26 91.5 0.7 2.5e-26 91.5 0.5 4.3 5 0 0 5 5 5 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAM20068.1 - 6.9e-07 29.3 0.0 1.9e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain SpoU_methylase PF00588.14 GAM20069.1 - 1.3e-34 119.0 0.0 2.2e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 GAM20069.1 - 1.6e-09 37.8 0.0 0.0025 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding Syntaxin PF00804.20 GAM20070.1 - 1.1e-12 48.0 6.2 1.1e-12 48.0 4.3 3.6 3 2 1 4 4 4 1 Syntaxin SNARE PF05739.14 GAM20070.1 - 5.3e-12 45.2 5.1 2.8e-11 42.9 0.4 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 GAM20070.1 - 2.9 7.9 24.6 0.97 9.4 0.9 3.1 3 0 0 3 3 3 0 Syntaxin-like protein Ank_2 PF12796.2 GAM20071.1 - 1.9e-12 47.3 1.8 0.00065 19.9 0.0 4.5 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20071.1 - 6.6e-05 23.3 2.4 1.9 9.1 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20071.1 - 7.1e-05 22.6 4.8 9.7 6.7 0.0 6.4 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.25 GAM20071.1 - 0.0038 16.9 4.9 46 4.0 0.0 6.2 6 0 0 6 6 6 0 Ankyrin repeat Pho86 PF11124.3 GAM20071.1 - 0.0086 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Ank_5 PF13857.1 GAM20071.1 - 0.0086 16.3 2.5 4.8 7.5 0.0 4.7 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM20072.1 - 3.8e-07 30.3 1.1 0.056 13.7 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20072.1 - 1.2e-05 25.6 6.6 0.0091 16.4 0.2 5.2 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM20072.1 - 2e-05 24.1 0.4 7 6.6 0.0 5.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 GAM20072.1 - 3.8e-05 23.7 5.3 34 4.8 0.0 6.9 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20072.1 - 6.3e-05 22.8 2.5 2.3 8.6 0.0 7.2 9 1 0 9 9 9 1 Ankyrin repeat Cyclin_N PF00134.18 GAM20073.1 - 1.9e-11 43.6 0.0 3.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAM20073.1 - 1e-10 42.2 0.0 1.6e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Cyclin Apolipoprotein PF01442.13 GAM20074.1 - 0.0097 15.4 0.1 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SlyX PF04102.7 GAM20074.1 - 0.027 14.8 0.1 7.6 6.9 0.0 2.5 1 1 1 2 2 2 0 SlyX Usp PF00582.21 GAM20076.1 - 6.2e-24 84.7 0.1 1.3e-22 80.5 0.1 2.0 1 1 0 1 1 1 1 Universal stress protein family RhoGEF PF00621.15 GAM20077.1 - 1.7e-43 148.5 6.8 1.7e-43 148.5 4.7 2.1 3 0 0 3 3 3 1 RhoGEF domain CH PF00307.26 GAM20077.1 - 6.2e-07 29.4 0.1 2.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 GAM20077.1 - 0.0001 21.5 0.2 0.00023 20.5 0.2 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif FCH PF00611.18 GAM20077.1 - 0.0014 18.7 2.7 0.015 15.4 0.3 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Ank_2 PF12796.2 GAM20078.1 - 7.1e-09 35.8 0.4 0.055 13.8 0.0 4.4 2 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM20079.1 - 9.6e-05 22.6 0.2 0.19 12.0 0.0 4.5 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20079.1 - 0.0009 19.2 0.2 1.7 9.1 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.2 GAM20081.1 - 4.2e-06 27.0 0.4 0.37 11.1 0.1 3.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20081.1 - 4.1e-05 23.4 0.7 12 6.5 0.0 5.6 4 1 1 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 GAM20081.1 - 0.00051 20.4 1.4 19 5.9 0.0 5.5 5 2 0 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20081.1 - 0.0019 18.3 0.2 58 4.1 0.0 5.1 5 1 0 5 5 5 0 Ankyrin repeats (many copies) RhoGAP PF00620.22 GAM20083.1 - 3.4e-06 26.7 0.9 1.1e-05 25.1 0.6 1.9 1 0 0 1 1 1 1 RhoGAP domain MTS PF05175.9 GAM20084.1 - 5e-16 58.5 0.0 6.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM20084.1 - 2.6e-11 43.5 0.0 3.6e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM20084.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM20084.1 - 1.4e-08 34.6 0.0 2.3e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM20084.1 - 9.7e-08 31.4 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 GAM20084.1 - 6.3e-07 29.8 0.0 4.3e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM20084.1 - 1.3e-06 28.9 0.0 1.9e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM20084.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 GAM20084.1 - 9.4e-05 22.0 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 GAM20084.1 - 0.00029 21.1 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAM20084.1 - 0.00049 19.3 0.0 0.0011 18.1 0.0 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB N6_N4_Mtase PF01555.13 GAM20084.1 - 0.0014 18.1 0.2 0.71 9.3 0.0 2.1 2 0 0 2 2 2 2 DNA methylase Methyltransf_12 PF08242.7 GAM20084.1 - 0.0014 19.0 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.4 GAM20084.1 - 0.0036 17.2 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Cons_hypoth95 PF03602.10 GAM20084.1 - 0.0048 16.3 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.15 GAM20084.1 - 0.011 14.8 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 GAM20084.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 GAM20084.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF4611 PF15387.1 GAM20085.1 - 9.8 6.4 23.1 5.6 7.1 4.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Tetraspannin PF00335.15 GAM20086.1 - 0.024 13.9 1.2 0.04 13.1 0.8 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF1206 PF06724.6 GAM20086.1 - 0.18 11.5 2.0 19 5.0 0.7 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF2207 PF09972.4 GAM20086.1 - 2.2 6.7 6.2 0.25 9.8 1.4 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF4661 PF15576.1 GAM20086.1 - 3.6 7.1 8.3 6.8 6.2 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TFIIA PF03153.8 GAM20086.1 - 3.7 7.3 24.3 4.7 6.9 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit vATP-synt_AC39 PF01992.11 GAM20087.1 - 3.1e-97 325.7 0.4 3.5e-97 325.5 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CH PF00307.26 GAM20088.1 - 2.1e-10 40.5 0.0 5.1e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4470 PF14737.1 GAM20089.1 - 0.03 14.0 0.0 0.22 11.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4470) Proteasom_Rpn13 PF04683.8 GAM20090.1 - 4e-19 68.4 0.2 6.5e-19 67.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Rubella_E2 PF05749.6 GAM20090.1 - 1.8 7.7 3.9 3 7.0 2.7 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 RNA_pol_Rpb1_1 PF04997.7 GAM20091.1 - 1.6e-119 399.1 1.2 2.9e-119 398.2 0.8 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 GAM20091.1 - 2.3e-108 361.6 0.0 2.3e-108 361.6 0.0 1.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 GAM20091.1 - 1.7e-71 239.5 1.3 2.4e-71 239.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 GAM20091.1 - 1.4e-59 200.9 0.0 2.6e-59 200.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 GAM20091.1 - 3.8e-49 166.4 0.0 8.6e-49 165.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 GAM20091.1 - 1e-39 135.3 5.4 2.5e-39 134.0 3.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 GAM20091.1 - 2.7e-37 126.8 0.9 2.7e-37 126.8 0.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 GAM20091.1 - 1.4e-09 37.2 279.8 0.26 11.5 10.2 14.1 6 2 9 18 18 18 16 RNA polymerase Rpb1 C-terminal repeat Pept_tRNA_hydro PF01195.14 GAM20092.1 - 1.9e-14 53.5 0.0 2.7e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase tRNA_anti-codon PF01336.20 GAM20093.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Mlo PF03094.10 GAM20094.1 - 0.55 8.2 4.9 0.97 7.4 3.4 1.3 1 0 0 1 1 1 0 Mlo family SNARE PF05739.14 GAM20095.1 - 5.3e-09 35.6 4.7 1e-08 34.6 3.2 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.1 GAM20095.1 - 5e-05 23.2 3.1 5e-05 23.2 2.2 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Prominin PF05478.6 GAM20095.1 - 0.00096 16.8 0.2 0.00096 16.8 0.1 1.5 2 0 0 2 2 2 1 Prominin LXG PF04740.7 GAM20095.1 - 0.048 13.4 0.6 0.048 13.4 0.4 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.7 GAM20095.1 - 0.5 10.1 4.6 0.22 11.3 0.7 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3139 PF11337.3 GAM20095.1 - 4.2 7.7 7.4 2.3 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Bacillus_HBL PF05791.6 GAM20095.1 - 4.5 6.6 8.7 1.7 7.9 0.8 2.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) adh_short PF00106.20 GAM20096.1 - 3.8e-27 95.2 0.0 4.9e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM20096.1 - 3.8e-11 42.9 0.1 6.1e-10 39.0 0.1 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM20096.1 - 5e-06 26.4 0.1 9.1e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase A-2_8-polyST PF07388.6 GAM20096.1 - 0.017 13.4 0.3 0.023 13.0 0.2 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) Eno-Rase_NADH_b PF12242.3 GAM20096.1 - 0.023 14.4 1.0 0.062 13.1 0.2 2.0 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 GAM20096.1 - 0.025 14.0 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CW_binding_2 PF04122.7 GAM20096.1 - 0.025 14.7 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Beta-Casp PF10996.3 GAM20097.1 - 1.7e-10 40.9 0.0 4.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain PA14 PF07691.7 GAM20098.1 - 1.8e-10 40.6 1.0 3.8e-10 39.5 0.7 1.5 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM20098.1 - 0.016 15.0 6.3 0.016 15.0 4.3 12.7 13 1 0 13 13 13 0 Dictyostelium (slime mold) repeat OppC_N PF12911.2 GAM20098.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Dict-STAT-coil PF09267.5 GAM20099.1 - 1.3e-41 141.3 16.4 1.3e-41 141.3 11.4 4.2 4 1 1 5 5 5 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 GAM20099.1 - 3.9e-11 42.5 0.0 1.3e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 SH2 domain GOLD_2 PF13897.1 GAM20099.1 - 0.21 11.8 3.4 0.48 10.6 2.4 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Serinc PF03348.10 GAM20099.1 - 2 7.0 7.4 4.1 6.0 5.1 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) EphA2_TM PF14575.1 GAM20099.1 - 3 8.3 7.2 13 6.2 5.0 2.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OATP PF03137.15 GAM20099.1 - 3.4 5.5 8.1 5.9 4.8 5.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.17 GAM20099.1 - 4.7 6.1 5.9 8.1 5.3 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Apolipoprotein PF01442.13 GAM20100.1 - 0.0012 18.4 0.9 0.0019 17.7 0.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Matrilin_ccoil PF10393.4 GAM20100.1 - 0.0023 17.2 6.4 0.16 11.3 4.4 2.4 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Phage_GPO PF05929.6 GAM20100.1 - 0.0088 15.3 0.5 0.0096 15.2 0.3 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.7 GAM20100.1 - 0.016 15.0 10.4 0.03 14.1 2.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bac_small_YrzI PF09501.5 GAM20100.1 - 0.031 14.1 0.5 0.11 12.4 0.0 2.2 2 0 0 2 2 1 0 Probable sporulation protein (Bac_small_yrzI) Hema_stalk PF08720.5 GAM20100.1 - 0.062 12.8 0.2 0.082 12.4 0.2 1.3 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk NPV_P10 PF05531.7 GAM20100.1 - 0.066 13.4 12.1 0.039 14.2 3.7 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF842 PF05811.8 GAM20100.1 - 0.1 12.0 2.8 0.26 10.7 2.0 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Fzo_mitofusin PF04799.8 GAM20100.1 - 0.11 11.9 7.3 0.08 12.3 3.4 1.8 1 1 1 2 2 2 0 fzo-like conserved region Phasin PF05597.6 GAM20100.1 - 0.12 12.1 5.6 0.23 11.2 3.9 1.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.6 GAM20100.1 - 0.27 11.2 7.3 0.2 11.6 2.0 1.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) IFP_35_N PF07334.8 GAM20100.1 - 0.3 11.0 3.8 0.77 9.7 2.6 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Laminin_II PF06009.7 GAM20100.1 - 0.3 10.8 8.5 0.18 11.5 1.4 2.0 1 1 1 2 2 2 0 Laminin Domain II M PF02370.11 GAM20100.1 - 0.47 10.9 0.3 0.47 10.9 0.2 3.9 2 1 1 4 4 4 0 M protein repeat DUF1690 PF07956.6 GAM20100.1 - 0.68 9.9 7.5 0.95 9.4 4.8 1.4 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DUF972 PF06156.8 GAM20100.1 - 0.99 9.7 6.3 7.3 6.9 4.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Cytochrom_B562 PF07361.6 GAM20100.1 - 2.2 8.7 6.2 27 5.2 4.3 2.2 1 1 0 1 1 1 0 Cytochrome b562 bZIP_1 PF00170.16 GAM20100.1 - 2.9 7.9 7.7 6.4 6.8 1.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF1664 PF07889.7 GAM20100.1 - 3.5 7.4 7.4 19 5.1 5.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HSBP1 PF06825.7 GAM20100.1 - 4.3 6.9 6.3 0.86 9.2 0.2 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PC_rep PF01851.17 GAM20101.1 - 1.3e-26 91.3 18.4 0.0012 18.9 0.0 10.6 11 0 0 11 11 11 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAM20101.1 - 2.4e-09 37.3 2.0 0.0042 17.3 0.0 4.5 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 GAM20101.1 - 7.5e-06 25.6 0.0 2 8.6 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.15 GAM20101.1 - 0.005 15.2 0.0 1.9 6.7 0.0 2.3 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 GAM20101.1 - 0.085 13.3 5.2 2.8 8.5 0.1 4.1 3 1 1 4 4 4 0 HEAT-like repeat Pkinase PF00069.20 GAM20102.1 - 1.9e-43 148.4 0.0 7.5e-29 100.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20102.1 - 4.7e-28 97.9 0.0 6.1e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM20102.1 - 0.0032 16.4 0.0 0.0077 15.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 GAM20102.1 - 0.033 12.9 0.9 0.05 12.3 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase TSA PF03249.8 GAM20102.1 - 0.42 9.1 2.6 0.73 8.2 1.8 1.3 1 0 0 1 1 1 0 Type specific antigen Macoilin PF09726.4 GAM20102.1 - 2 6.5 7.8 2.6 6.2 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein COesterase PF00135.23 GAM20103.1 - 1.2e-108 364.2 1.1 1.5e-108 363.8 0.8 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM20103.1 - 6.2e-08 32.4 0.1 1.8e-07 30.9 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM20103.1 - 0.014 14.6 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM20103.1 - 0.045 13.4 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec63 PF02889.11 GAM20104.1 - 1.7e-38 132.6 3.2 1.4e-29 103.3 1.8 2.1 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 GAM20104.1 - 5.5e-21 74.0 0.1 1.4e-20 72.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain Neur_chan_memb PF02932.11 GAM20104.1 - 3.7 7.3 7.0 8.2 6.2 4.9 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GRASP55_65 PF04495.9 GAM20105.1 - 1.6e-67 225.7 0.1 7.4e-48 162.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 GAM20105.1 - 0.0017 18.1 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain GHMP_kinases_N PF00288.21 GAM20106.1 - 9.3e-12 44.8 0.6 1.7e-11 43.9 0.4 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM20106.1 - 0.00029 20.9 0.0 0.00061 19.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal RasGEF PF00617.14 GAM20108.1 - 2.3e-58 197.0 0.1 5e-58 195.9 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM20108.1 - 2.2e-19 69.4 1.2 2.2e-19 69.4 0.8 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif AAA_16 PF13191.1 GAM20109.1 - 7.2e-10 39.1 0.0 2e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_11 PF13414.1 GAM20110.1 - 1.4e-42 143.1 20.9 2.7e-18 65.3 0.1 5.4 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM20110.1 - 2.8e-31 105.8 18.3 2.5e-08 33.1 0.2 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20110.1 - 8e-29 97.2 18.8 1e-06 28.2 0.2 7.9 9 0 0 9 9 8 4 Tetratricopeptide repeat DnaJ PF00226.26 GAM20110.1 - 6e-26 89.9 1.8 2.4e-25 88.0 1.3 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 GAM20110.1 - 7.9e-14 51.7 19.3 0.00022 21.5 0.2 6.4 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20110.1 - 5.9e-13 49.1 1.6 1e-05 26.0 0.0 5.3 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20110.1 - 2.3e-12 45.7 23.2 2.2e-05 23.9 0.1 7.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20110.1 - 3.6e-11 42.6 0.9 0.019 15.5 0.0 6.8 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20110.1 - 3e-10 39.9 14.3 0.0086 15.9 0.1 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20110.1 - 8.7e-09 34.5 1.6 0.28 11.0 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM20110.1 - 1.2e-08 34.9 20.4 7.4e-05 22.8 2.2 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAM20110.1 - 2.8e-08 33.3 16.4 7.5e-05 22.6 0.0 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM20110.1 - 1.9e-06 27.6 0.1 0.03 14.1 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAM20110.1 - 0.00037 19.6 12.5 0.0043 16.1 0.4 4.0 1 1 2 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 GAM20110.1 - 0.0043 17.3 0.1 0.23 11.7 0.1 3.3 3 2 1 4 4 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 GAM20110.1 - 0.012 15.4 13.6 0.031 14.1 0.0 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 GAM20110.1 - 0.58 10.0 12.8 1.6 8.6 0.1 5.1 5 1 0 5 5 3 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 GAM20110.1 - 0.93 9.6 10.9 7.6 6.7 0.0 4.3 3 2 1 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM20110.1 - 1 8.6 6.9 29 4.0 0.1 4.2 5 0 0 5 5 5 0 SHNi-TPR TPR_6 PF13174.1 GAM20110.1 - 1.1 9.8 18.5 1.2 9.7 0.3 6.4 8 1 0 8 8 6 0 Tetratricopeptide repeat SR-25 PF10500.4 GAM20110.1 - 4.9 6.5 8.6 0.57 9.6 2.8 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Choline_transpo PF04515.7 GAM20111.1 - 8e-71 238.4 33.9 1.1e-70 238.0 19.2 2.4 1 1 1 2 2 2 2 Plasma-membrane choline transporter FGGY_N PF00370.16 GAM20112.1 - 2.5e-31 108.8 0.1 6.8e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 GAM20112.1 - 4.6e-30 104.7 2.3 1.3e-23 83.7 1.0 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 GAM20112.1 - 0.00019 20.8 0.2 0.025 13.8 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 GAM20112.1 - 0.015 14.2 0.1 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Cnd1 PF12717.2 GAM20113.1 - 8.4e-09 35.5 8.7 0.0014 18.5 0.0 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM20113.1 - 0.00026 20.7 1.2 17 5.8 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 GAM20113.1 - 0.038 14.4 0.1 1.3e+02 3.2 0.0 5.3 4 1 1 5 5 5 0 HEAT-like repeat SMC_N PF02463.14 GAM20114.1 - 9.9e-56 188.4 8.4 2.3e-55 187.2 5.8 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM20114.1 - 1.8e-23 82.8 0.0 1e-22 80.3 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAM20114.1 - 4.7e-14 53.0 16.9 2.2e-08 34.4 0.1 3.9 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 GAM20114.1 - 0.0028 18.0 58.5 0.0028 18.0 40.6 5.7 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 GAM20114.1 - 0.0037 16.7 0.1 0.0084 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM20114.1 - 0.19 12.0 0.0 0.19 12.0 0.0 6.2 3 2 0 3 3 3 0 ABC transporter Reo_sigmaC PF04582.7 GAM20114.1 - 0.35 9.9 31.5 0.44 9.6 3.9 4.5 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Kelch_4 PF13418.1 GAM20115.1 - 1.5e-12 47.0 7.0 7.3e-07 28.8 0.0 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM20115.1 - 5.9e-12 45.2 5.8 3.4e-05 23.8 0.0 4.6 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM20115.1 - 2.4e-10 39.7 1.5 0.0011 18.3 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM20115.1 - 5.1e-08 32.3 0.3 0.11 12.3 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 GAM20115.1 - 6.4e-06 26.1 3.4 0.12 12.5 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM20115.1 - 0.00029 20.6 7.9 0.49 10.4 0.2 3.8 4 0 0 4 4 4 3 Kelch motif DUF1900 PF08954.6 GAM20115.1 - 0.0082 15.6 0.2 0.29 10.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) Glyoxalase PF00903.20 GAM20116.1 - 2.5e-24 85.6 0.0 2.9e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM20116.1 - 7.5e-18 65.1 0.0 8.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAM20116.1 - 5.8e-11 42.3 0.0 1.4e-10 41.1 0.0 1.6 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 GAM20116.1 - 0.0015 18.1 0.0 0.0019 17.8 0.0 1.3 1 1 0 1 1 1 1 CppA N-terminal Glyoxalase_3 PF13468.1 GAM20116.1 - 0.0054 16.6 0.0 0.2 11.5 0.0 2.0 1 1 0 2 2 2 1 Glyoxalase-like domain Kelch_6 PF13964.1 GAM20117.1 - 7e-19 67.1 3.0 0.00014 21.8 0.0 5.5 3 1 2 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM20117.1 - 1e-13 50.8 1.5 0.0053 16.4 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM20117.1 - 3e-11 42.9 4.3 0.014 15.3 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM20117.1 - 4.1e-10 39.0 4.9 0.003 17.0 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM20117.1 - 4.3e-07 29.9 0.4 0.26 11.4 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM20117.1 - 6.1e-06 25.7 4.6 0.5 10.2 0.0 4.6 4 1 1 5 5 4 3 Kelch motif FlgN PF05130.7 GAM20117.1 - 0.0087 16.3 1.9 1.3 9.2 0.4 2.2 2 0 0 2 2 2 1 FlgN protein zf-His_Me_endon PF05551.6 GAM20117.1 - 0.027 14.4 0.3 0.062 13.2 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease FLO_LFY PF01698.11 GAM20117.1 - 0.044 12.6 3.6 0.086 11.6 2.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1664 PF07889.7 GAM20117.1 - 0.2 11.4 1.7 0.54 10.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YlqD PF11068.3 GAM20117.1 - 0.79 9.7 7.0 0.22 11.5 2.5 1.7 2 0 0 2 2 2 0 YlqD protein RNA_pol_Rpb1_5 PF04998.12 GAM20117.1 - 1.1 8.4 4.2 1.8 7.7 2.9 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 GatB_Yqey PF02637.13 GAM20117.1 - 1.2 8.8 5.8 0.14 11.8 0.9 1.7 2 0 0 2 2 2 0 GatB domain IncA PF04156.9 GAM20117.1 - 1.7 8.2 5.8 3.4 7.2 4.0 1.5 1 0 0 1 1 1 0 IncA protein FAM176 PF14851.1 GAM20117.1 - 2.7 7.6 6.0 8 6.1 4.2 1.8 1 0 0 1 1 1 0 FAM176 family Aspzincin_M35 PF14521.1 GAM20118.1 - 0.085 13.3 3.4 0.68 10.4 0.2 2.4 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Kelch_4 PF13418.1 GAM20119.1 - 1e-13 50.7 2.4 1.4e-05 24.7 0.0 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM20119.1 - 5.7e-11 42.1 10.7 2.6e-06 27.3 0.1 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM20119.1 - 3.7e-10 39.1 6.8 0.00023 20.6 0.0 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 GAM20119.1 - 1.3e-08 34.6 6.8 0.0027 17.5 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM20119.1 - 2e-07 30.9 2.5 0.0017 18.4 0.0 4.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM20119.1 - 1.7e-06 27.5 1.0 0.02 14.6 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Laminin_EGF PF00053.19 GAM20120.1 - 3.9e-05 23.4 21.6 0.0032 17.3 0.5 3.4 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) hEGF PF12661.2 GAM20120.1 - 0.0025 17.7 19.7 0.0074 16.3 4.0 3.4 3 0 0 3 3 3 2 Human growth factor-like EGF Kelch_6 PF13964.1 GAM20121.1 - 4.1e-14 52.0 5.2 0.00037 20.5 0.1 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM20121.1 - 2.1e-09 36.9 3.2 0.044 13.5 0.0 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM20121.1 - 4.5e-09 35.7 2.4 0.018 14.5 0.0 3.8 3 0 0 3 3 3 3 Kelch motif zf-B_box PF00643.19 GAM20121.1 - 6e-09 35.6 7.3 1.2e-08 34.7 5.1 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_3 PF13415.1 GAM20121.1 - 9.6e-07 28.8 1.8 0.4 10.9 0.2 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM20121.1 - 3.4e-05 23.6 3.5 1.4 8.9 0.7 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM20121.1 - 0.00092 18.8 0.7 0.31 10.8 0.0 3.5 3 0 0 3 3 3 1 Kelch motif IBR PF01485.16 GAM20121.1 - 0.048 13.5 4.2 0.16 11.8 2.9 1.9 1 0 0 1 1 1 0 IBR domain Syja_N PF02383.13 GAM20122.1 - 3.7e-86 288.7 0.4 3.7e-86 288.7 0.3 1.4 2 0 0 2 2 2 1 SacI homology domain F-actin_cap_A PF01267.12 GAM20123.1 - 6.2e-84 281.2 0.1 7.3e-84 281.0 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Gemini_C4 PF01492.12 GAM20123.1 - 0.082 12.6 1.5 1.7 8.4 0.0 2.6 3 0 0 3 3 3 0 Geminivirus C4 protein Glyco_transf_22 PF03901.12 GAM20124.1 - 2.6e-78 263.9 32.3 3.3e-78 263.5 22.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3237 PF11578.3 GAM20125.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) NAD_kinase PF01513.16 GAM20126.1 - 8.7e-59 198.6 0.0 1.2e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 GAM20126.1 - 0.09 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Acetyltransf_7 PF13508.1 GAM20127.1 - 2.4e-10 40.4 0.4 4.2e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM20127.1 - 3.4e-05 23.9 0.0 8.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM20127.1 - 8.3e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 GAM20127.1 - 0.0052 16.6 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM20127.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM20127.1 - 0.04 13.8 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 GAM20127.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Endotoxin_N PF03945.9 GAM20128.1 - 8.7e-10 38.3 1.3 1.4e-09 37.6 0.9 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain IcmL PF11393.3 GAM20129.1 - 0.039 13.9 0.1 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein DGF-1_5 PF11038.3 GAM20129.1 - 0.059 12.5 0.1 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Methyltrn_RNA_3 PF02598.12 GAM20130.1 - 2.1e-47 161.8 0.0 5.1e-47 160.6 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methyltransferase VWA_3 PF13768.1 GAM20130.1 - 3.5e-28 98.2 0.0 8e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 GAM20130.1 - 8.1e-20 70.6 0.0 2.4e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAM20130.1 - 2.3e-13 50.2 0.0 6.8e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 GAM20130.1 - 3.2e-09 37.1 0.0 7.2e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAM20130.1 - 1e-06 28.7 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 vWA found in TerF C terminus VIT_2 PF13757.1 GAM20130.1 - 1.3e-06 27.7 0.0 4.2e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 GAM20130.1 - 4.7e-06 25.9 0.0 8.3e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Prenyltrans_1 PF13243.1 GAM20130.1 - 0.0055 16.6 0.1 0.027 14.4 0.1 2.1 2 0 0 2 2 2 1 Prenyltransferase-like CobT_C PF11775.3 GAM20130.1 - 0.035 13.5 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain DUF2201 PF09967.4 GAM20130.1 - 0.043 13.8 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 VWA-like domain (DUF2201) AAA_23 PF13476.1 GAM20130.1 - 0.045 14.0 13.3 0.1 12.9 9.2 1.5 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 GAM20130.1 - 0.81 8.5 9.8 1.6 7.5 6.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Voltage_CLC PF00654.15 GAM20131.1 - 1e-63 215.5 32.2 5.3e-63 213.1 20.6 2.2 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAM20131.1 - 2.8e-05 23.8 0.0 6.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 CBS domain DUF3246 PF11596.3 GAM20131.1 - 1 8.5 12.1 1.8 7.7 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ham1p_like PF01725.11 GAM20132.1 - 3.3e-49 166.8 0.0 3.7e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family EB PF01683.13 GAM20133.1 - 0.0068 16.4 3.7 0.018 15.1 2.5 1.6 1 0 0 1 1 1 1 EB module Med19 PF10278.4 GAM20134.1 - 2.3e-05 24.1 14.2 2.3e-05 24.1 9.8 2.5 1 1 1 2 2 2 1 Mediator of RNA pol II transcription subunit 19 IpaD PF06511.6 GAM20134.1 - 0.017 14.1 1.9 0.026 13.5 1.3 1.2 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Band_3_cyto PF07565.8 GAM20134.1 - 4.6 6.6 9.0 7.3 6.0 6.3 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain FYVE PF01363.16 GAM20135.1 - 6.6e-18 64.3 9.7 1.4e-17 63.3 6.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_C PF02752.17 GAM20135.1 - 0.00027 21.0 0.2 0.00072 19.6 0.2 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain FYVE_2 PF02318.11 GAM20135.1 - 0.0025 17.6 7.4 0.0047 16.8 5.2 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger Arrestin_N PF00339.24 GAM20135.1 - 0.0037 17.0 0.2 0.0037 17.0 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LicD PF04991.8 GAM20135.1 - 0.029 14.4 0.8 0.052 13.6 0.5 1.3 1 0 0 1 1 1 0 LicD family Menin PF05053.8 GAM20135.1 - 0.23 9.5 10.1 0.33 9.0 7.0 1.1 1 0 0 1 1 1 0 Menin Mem_trans PF03547.13 GAM20135.1 - 0.27 9.4 6.0 0.43 8.8 4.2 1.2 1 0 0 1 1 1 0 Membrane transport protein zf-C3HC4_2 PF13923.1 GAM20135.1 - 0.5 10.4 9.2 1.5 8.9 6.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM20135.1 - 0.56 10.0 11.8 0.55 10.1 5.2 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 GAM20135.1 - 2.3 8.0 11.9 4.7 7.0 8.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CobT PF06213.7 GAM20135.1 - 7.8 5.5 9.1 11 5.0 6.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Kelch_4 PF13418.1 GAM20136.1 - 9.1e-13 47.7 0.3 1.1e-06 28.3 0.1 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM20136.1 - 5.6e-12 45.2 2.1 0.0011 19.0 0.0 4.0 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 GAM20136.1 - 2e-09 36.8 0.0 0.0002 20.8 0.0 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 GAM20136.1 - 1.5e-07 31.4 0.2 0.32 11.2 0.0 3.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM20136.1 - 1.7e-06 27.8 7.5 0.005 16.7 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM20136.1 - 2.4e-06 27.0 0.7 2.5 7.9 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 GAM20137.1 - 1.5e-16 59.8 6.4 1.8e-05 24.7 0.1 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM20137.1 - 8.3e-10 38.2 6.4 1.7e-06 27.6 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM20137.1 - 3.9e-08 33.2 1.1 0.0042 17.2 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM20137.1 - 4.8e-08 32.4 5.8 0.011 15.2 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 GAM20137.1 - 2.8e-05 23.7 6.1 0.16 11.8 0.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 GAM20137.1 - 0.00011 22.0 7.1 0.9 9.5 0.1 4.1 4 0 0 4 4 4 3 Kelch motif DUF1241 PF06840.6 GAM20138.1 - 0.083 12.1 0.2 0.087 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Pkinase_Tyr PF07714.12 GAM20139.1 - 0.13 11.2 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_A22B PF04258.8 GAM20140.1 - 5.6e-34 117.9 6.2 6.6e-34 117.7 4.3 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DctQ PF04290.7 GAM20141.1 - 0.04 13.6 0.1 0.04 13.6 0.1 2.1 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sre PF03125.13 GAM20141.1 - 0.057 12.3 2.5 0.072 12.0 0.5 1.8 2 0 0 2 2 2 0 C. elegans Sre G protein-coupled chemoreceptor DUF1673 PF07895.6 GAM20141.1 - 3.3 7.2 6.3 18 4.7 4.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4491 PF14898.1 GAM20141.1 - 4.7 7.4 5.9 1.5 9.0 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) DEAD PF00270.24 GAM20142.1 - 5.2e-33 113.9 0.3 5.2e-33 113.9 0.2 3.2 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM20142.1 - 1.6e-24 85.5 0.1 7.8e-24 83.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RskA PF10099.4 GAM20142.1 - 0.14 11.8 10.0 0.037 13.7 3.8 2.4 3 0 0 3 3 3 0 Anti-sigma-K factor rskA DUF4632 PF15451.1 GAM20142.1 - 0.69 9.8 7.4 1.6 8.7 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DUF4506 PF14958.1 GAM20143.1 - 2.5e-11 43.3 0.9 2.5e-11 43.3 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4506) RdRP PF05183.7 GAM20144.1 - 5.8e-131 438.0 0.0 1e-130 437.1 0.0 1.4 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.26 GAM20144.1 - 1.1e-13 50.7 0.1 3.6e-13 49.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM20144.1 - 1.4e-13 50.7 0.1 4.8e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM20144.1 - 1.2e-08 35.0 0.0 2.9e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NTP_transf_2 PF01909.18 GAM20144.1 - 0.027 14.7 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain EGF PF00008.22 GAM20145.1 - 3.2 7.8 7.4 18 5.4 5.1 2.0 1 1 0 1 1 1 0 EGF-like domain Asp PF00026.18 GAM20147.1 - 1.2e-109 366.4 0.4 1.4e-109 366.1 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM20147.1 - 9e-09 35.4 0.1 1.4e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAM20147.1 - 4.4e-05 23.0 0.0 0.00022 20.7 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 GAM20147.1 - 0.0022 18.4 0.1 0.051 14.0 0.1 3.0 2 1 0 2 2 2 1 Aspartyl protease ArfGap PF01412.13 GAM20148.1 - 4.1e-11 42.6 0.1 4.1e-11 42.6 0.1 3.5 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf Endonuclease_7 PF02945.10 GAM20148.1 - 0.033 13.8 1.6 0.084 12.5 1.1 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII MoaE PF02391.12 GAM20149.1 - 5.2e-35 119.7 0.2 7.7e-35 119.2 0.1 1.3 1 0 0 1 1 1 1 MoaE protein BOP1NT PF08145.7 GAM20150.1 - 2.2e-91 306.1 13.9 2.2e-91 306.1 9.7 2.6 2 1 1 3 3 3 1 BOP1NT (NUC169) domain WD40 PF00400.27 GAM20150.1 - 4e-34 115.2 3.7 4.9e-13 48.4 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM20150.1 - 0.00097 18.8 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A MSP1_C PF07462.6 GAM20150.1 - 0.001 17.5 12.1 0.001 17.5 8.4 1.7 2 0 0 2 2 2 1 Merozoite surface protein 1 (MSP1) C-terminus MULE PF10551.4 GAM20150.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 MULE transposase domain CDC27 PF09507.5 GAM20150.1 - 1.7 7.7 44.4 4.6 6.3 30.8 1.7 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Myosin_TH1 PF06017.8 GAM20151.1 - 6e-36 123.6 3.4 2e-34 118.6 1.3 2.2 2 0 0 2 2 2 2 Myosin tail hSac2 PF12456.3 GAM20151.1 - 0.005 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Inositol phosphatase VWA_3 PF13768.1 GAM20152.1 - 1e-25 90.2 0.0 2.8e-25 88.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain MIF4G PF02854.14 GAM20152.1 - 2.8e-24 85.7 9.5 2.8e-24 85.7 6.6 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 GAM20152.1 - 3.3e-18 65.4 2.4 6.7e-18 64.4 0.3 2.7 2 0 0 2 2 2 1 MA3 domain VWA PF00092.23 GAM20152.1 - 8.7e-13 48.3 0.1 3.8e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAM20152.1 - 0.0028 17.5 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 GAM20152.1 - 0.039 13.1 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Med25_VWA PF11265.3 GAM20153.1 - 3.5e-20 71.9 0.1 9.5e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Pkinase_Tyr PF07714.12 GAM20154.1 - 3e-35 121.5 0.0 4.9e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM20154.1 - 2.2e-30 105.6 0.0 4.6e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.18 GAM20154.1 - 4.1e-07 29.5 4.0 0.00043 19.9 0.1 4.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM20154.1 - 0.0051 17.0 0.7 3.5 7.9 0.1 3.0 1 1 0 2 2 2 2 HEAT repeats RWP-RK PF02042.10 GAM20155.1 - 3.6e-05 23.4 0.2 7.9e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.14 GAM20155.1 - 0.012 15.1 0.4 0.023 14.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family DUF1462 PF07315.6 GAM20155.1 - 0.39 10.7 2.3 0.61 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) Glyco_hydro_18 PF00704.23 GAM20156.1 - 7.3e-06 25.6 0.5 3.9e-05 23.2 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Methyltransf_32 PF13679.1 GAM20156.1 - 0.086 12.5 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_M1 PF01433.15 GAM20156.1 - 0.16 11.0 0.9 0.25 10.4 0.6 1.2 1 0 0 1 1 1 0 Peptidase family M1 Pkinase PF00069.20 GAM20157.1 - 8.3e-30 103.7 0.0 1.5e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20157.1 - 3.2e-18 65.7 0.1 1.1e-17 63.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20157.1 - 1.5e-05 24.8 0.1 1.5e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease 2-5A RIO1 PF01163.17 GAM20157.1 - 0.016 14.5 0.2 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 GAM20157.1 - 0.033 13.2 0.6 0.074 12.1 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20157.1 - 0.055 13.1 0.1 0.055 13.1 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM20157.1 - 0.088 12.3 4.0 4.1 6.9 0.3 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase RAM PF15320.1 GAM20157.1 - 0.23 11.7 1.4 0.77 10.0 1.0 1.9 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein BTV_NS2 PF04514.7 GAM20157.1 - 0.66 8.8 5.2 1.2 7.9 3.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pkinase PF00069.20 GAM20158.1 - 6.5e-40 136.9 0.4 1.5e-39 135.7 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20158.1 - 3.9e-27 94.9 0.1 1.3e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20158.1 - 8.6e-14 51.5 4.7 2.2e-13 50.1 3.2 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A RIO1 PF01163.17 GAM20158.1 - 0.00074 18.9 0.2 0.0022 17.3 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM20158.1 - 0.0009 18.3 0.1 0.002 17.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20158.1 - 0.052 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Endotoxin_N PF03945.9 GAM20159.1 - 2.7e-18 66.1 0.0 5.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM20160.1 - 1.2e-19 70.6 0.0 2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_C PF03944.9 GAM20161.1 - 0.011 15.8 0.1 0.014 15.5 0.1 1.1 1 0 0 1 1 1 0 delta endotoxin MSP PF01716.13 GAM20161.1 - 0.029 13.4 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Endotoxin_N PF03945.9 GAM20163.1 - 1.4e-22 80.2 0.1 2e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM20164.1 - 2.6e-19 69.5 0.0 4.6e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Pkinase PF00069.20 GAM20165.1 - 3.9e-40 137.6 1.4 4.9e-40 137.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20165.1 - 2.9e-26 92.0 0.0 5.5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20165.1 - 1.4e-11 44.3 3.4 1.4e-11 44.3 2.4 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A RIO1 PF01163.17 GAM20165.1 - 0.00096 18.5 0.2 0.0026 17.1 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM20165.1 - 0.001 18.2 0.1 0.0021 17.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20165.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 GAM20167.1 - 1.9e-38 132.1 0.0 3.7e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20167.1 - 2.9e-26 92.0 0.0 4.6e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM20167.1 - 0.0028 16.7 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM20167.1 - 0.0041 16.4 0.1 0.012 14.9 0.1 1.7 1 0 0 1 1 1 1 RIO1 family Ribonuc_2-5A PF06479.7 GAM20167.1 - 0.0066 16.3 2.6 0.035 13.9 0.3 2.5 1 1 1 2 2 2 1 Ribonuclease 2-5A APH PF01636.18 GAM20167.1 - 0.061 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-alpha PF00503.15 GAM20168.1 - 7.7e-94 314.5 5.6 8.5e-94 314.3 3.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM20168.1 - 2.3e-12 46.5 0.1 5.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family EHN PF06441.7 GAM20168.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.7 2 1 0 3 3 3 0 Epoxide hydrolase N terminus Rad60-SLD PF11976.3 GAM20169.1 - 6.2e-23 80.2 0.0 7.7e-23 79.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM20169.1 - 6.6e-11 41.4 0.0 8.4e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UreE_N PF02814.10 GAM20169.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain RrnaAD PF00398.15 GAM20171.1 - 1e-60 205.0 0.0 1.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAM20171.1 - 3e-12 46.5 0.0 4.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM20171.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM20171.1 - 7e-06 25.7 0.0 1.6e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM20171.1 - 0.00011 22.5 0.0 0.00023 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM20171.1 - 0.00024 20.7 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 GAM20171.1 - 0.00027 20.1 0.0 0.00083 18.5 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAM20171.1 - 0.00031 20.1 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 GAM20171.1 - 0.0004 20.7 0.0 0.00093 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAM20171.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.1 GAM20171.1 - 0.0009 18.9 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM20171.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 GAM20171.1 - 0.0057 15.5 0.0 0.013 14.4 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase Met_10 PF02475.11 GAM20171.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 GAM20171.1 - 0.007 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 GAM20171.1 - 0.007 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DOT1 PF08123.8 GAM20171.1 - 0.013 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PrmA PF06325.8 GAM20171.1 - 0.031 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Zn_ribbon_2 PF12674.2 GAM20171.1 - 0.14 12.5 0.2 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain Homeobox PF00046.24 GAM20172.1 - 1.5e-19 69.3 4.2 2.7e-19 68.5 2.9 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAM20172.1 - 0.00092 18.8 0.3 0.0019 17.8 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Glu-tRNAGln PF02686.10 GAM20173.1 - 2.7e-09 36.6 0.2 4.2e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Sds3 PF08598.6 GAM20174.1 - 4.7e-23 81.8 19.3 4.7e-23 81.8 13.4 2.8 2 2 0 2 2 2 1 Sds3-like CBM49 PF09478.5 GAM20175.1 - 4.3e-06 26.7 0.4 6.1e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Pkinase_Tyr PF07714.12 GAM20176.1 - 2.8e-68 229.8 0.0 3.9e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM20176.1 - 2.8e-59 200.4 0.0 4.9e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.1 GAM20176.1 - 1.2e-34 117.6 22.1 1.5e-11 44.1 0.0 8.3 8 1 1 9 9 9 6 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM20176.1 - 5e-33 112.6 7.3 5.1e-12 45.3 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM20176.1 - 1.5e-30 104.5 6.2 1.3e-05 24.6 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 GAM20176.1 - 2.9e-30 103.7 0.7 0.00017 21.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM20176.1 - 4.6e-26 89.8 5.9 3.9e-06 26.7 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM20176.1 - 1.2e-22 78.6 9.3 6.4e-07 28.9 0.0 6.9 7 0 0 7 7 7 3 Kelch motif RIO1 PF01163.17 GAM20176.1 - 0.0093 15.3 0.1 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 GAM20176.1 - 0.016 14.2 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAM20176.1 - 0.033 13.2 0.1 0.056 12.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20176.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Serglycin PF04360.7 GAM20176.1 - 0.46 10.1 3.0 0.96 9.1 2.1 1.4 1 0 0 1 1 1 0 Serglycin CTP_transf_1 PF01148.15 GAM20177.1 - 4.3e-09 36.3 10.5 6.4e-09 35.8 7.3 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3593 PF12159.3 GAM20177.1 - 0.3 10.8 2.2 0.44 10.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) HemY_N PF07219.8 GAM20177.1 - 0.73 9.4 2.5 1.2 8.7 0.9 2.0 1 1 1 2 2 2 0 HemY protein N-terminus DUF2254 PF10011.4 GAM20177.1 - 2 6.7 5.5 1.7 7.0 1.6 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Endotoxin_N PF03945.9 GAM20178.1 - 8.3e-20 71.1 0.0 1.8e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Pkinase PF00069.20 GAM20179.1 - 4.6e-40 137.4 0.1 7.5e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20179.1 - 1.1e-28 100.0 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20179.1 - 1.2e-13 51.0 4.0 2.6e-13 49.9 2.8 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Kdo PF06293.9 GAM20179.1 - 0.00032 19.8 0.1 0.0006 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM20179.1 - 0.0028 17.0 0.2 0.007 15.7 0.1 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAM20179.1 - 0.077 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 GAM20180.1 - 3e-38 131.4 0.0 3e-38 131.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20180.1 - 8e-26 90.6 0.0 1.3e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20180.1 - 2.1e-11 43.7 1.9 2.1e-11 43.7 1.3 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A RIO1 PF01163.17 GAM20180.1 - 0.0033 16.7 0.2 0.0033 16.7 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 GAM20180.1 - 0.005 15.9 0.1 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20180.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4404 PF14357.1 GAM20180.1 - 1 9.8 5.5 9.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pkinase PF00069.20 GAM20181.1 - 1.4e-34 119.4 0.0 2.9e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20181.1 - 4.2e-21 75.1 0.0 1.3e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20181.1 - 3.3e-13 49.6 3.2 8.4e-13 48.3 2.2 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A DUF3384 PF11864.3 GAM20181.1 - 0.0016 16.9 0.2 0.0016 16.9 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3384) RIO1 PF01163.17 GAM20181.1 - 0.0062 15.8 0.2 0.014 14.7 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM20181.1 - 0.016 14.2 0.1 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20181.1 - 0.057 13.1 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 GAM20182.1 - 7.4e-39 133.4 1.3 8e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20182.1 - 5.1e-26 91.2 0.0 9.9e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20182.1 - 2.2e-12 46.9 3.3 2.2e-12 46.9 2.3 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.9 GAM20182.1 - 0.0055 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM20182.1 - 0.0073 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAM20182.1 - 0.024 14.3 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF605 PF04652.11 GAM20182.1 - 0.12 11.8 37.9 0.41 9.9 26.3 1.7 1 1 0 1 1 1 0 Vta1 like FAP PF07174.6 GAM20182.1 - 3.5 6.8 31.2 6.2 6.0 21.6 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Mito_carr PF00153.22 GAM20183.1 - 2.3e-71 235.5 0.7 4.5e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 GAM20184.1 - 1.3e-29 101.5 17.1 1.2e-14 53.7 2.0 4.1 3 1 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 GAM20184.1 - 5.9e-20 69.5 18.3 1.1e-05 24.9 0.2 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20184.1 - 1.3e-17 62.5 21.1 2.3e-08 33.3 0.6 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20184.1 - 3.6e-10 38.8 23.8 2.1e-05 23.9 0.9 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20184.1 - 8.9e-09 35.1 11.8 3.3e-06 26.9 0.6 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20184.1 - 3.1e-06 27.7 1.9 0.01 16.4 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM20184.1 - 3.6e-06 26.7 0.8 0.039 13.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20184.1 - 3.7e-06 27.1 0.2 2.6 8.4 0.0 4.0 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_3 PF07720.7 GAM20184.1 - 2.5e-05 23.9 14.1 0.059 13.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20184.1 - 5e-05 23.5 0.0 2.9 8.7 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM20184.1 - 0.00024 21.1 13.4 0.0014 18.7 3.4 3.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM20184.1 - 0.00025 20.8 0.0 7.8 6.4 0.0 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20184.1 - 0.00062 19.7 4.5 2.8 8.3 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM20184.1 - 0.00091 19.0 3.9 0.41 10.5 0.0 4.0 2 1 2 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 GAM20184.1 - 0.0015 18.8 5.8 4.1 8.0 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 GAM20184.1 - 0.0026 17.6 13.3 0.039 13.8 0.5 4.2 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain ICA69 PF04629.9 GAM20184.1 - 0.0064 16.4 17.0 0.0097 15.9 10.9 1.9 2 0 0 2 2 2 1 Islet cell autoantigen ICA69, C-terminal domain TPR_7 PF13176.1 GAM20184.1 - 0.015 15.0 4.8 6.3 6.8 0.0 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM20184.1 - 0.032 13.4 0.0 34 3.8 0.0 4.1 3 0 0 3 3 3 0 SHNi-TPR Gpi1 PF05024.10 GAM20184.1 - 0.16 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) DUF3856 PF12968.2 GAM20184.1 - 0.18 11.6 10.5 0.14 11.9 0.7 4.1 3 1 1 4 4 3 0 Domain of Unknown Function (DUF3856) BUD22 PF09073.5 GAM20184.1 - 1.1 8.3 20.9 1.6 7.6 14.5 1.2 1 0 0 1 1 1 0 BUD22 Dynactin_p22 PF07426.6 GAM20185.1 - 9.6e-05 21.7 3.4 9.6e-05 21.7 2.3 2.1 1 1 1 2 2 2 1 Dynactin subunit p22 bZIP_1 PF00170.16 GAM20185.1 - 3.7 7.5 5.6 7.5 6.6 0.1 3.5 3 1 1 4 4 4 0 bZIP transcription factor Med2 PF11214.3 GAM20185.1 - 5.2 7.1 10.3 7.2 6.7 0.1 2.6 2 1 0 2 2 2 0 Mediator complex subunit 2 VHP PF02209.14 GAM20186.1 - 3.9e-13 48.8 0.4 8.4e-13 47.7 0.3 1.6 1 0 0 1 1 1 1 Villin headpiece domain CRCB PF02537.10 GAM20187.1 - 1.7e-21 76.3 6.8 2.3e-21 75.8 4.7 1.2 1 0 0 1 1 1 1 CrcB-like protein GtrA PF04138.9 GAM20187.1 - 0.0079 16.1 4.4 2 8.4 1.5 2.2 1 1 1 2 2 2 2 GtrA-like protein HCV_NS4b PF01001.14 GAM20187.1 - 0.084 12.2 0.2 0.084 12.2 0.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b Polysacc_synt_C PF14667.1 GAM20187.1 - 0.084 12.6 8.0 0.11 12.2 5.5 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain MIP PF00230.15 GAM20189.1 - 1.4e-46 158.7 16.1 7.6e-46 156.4 11.2 1.9 1 1 0 1 1 1 1 Major intrinsic protein LIN37 PF15306.1 GAM20189.1 - 0.053 13.5 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 LIN37 DUF2721 PF11026.3 GAM20189.1 - 0.072 12.7 0.0 0.072 12.7 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) DctQ PF04290.7 GAM20189.1 - 2.9 7.6 13.6 0.42 10.3 3.2 3.2 2 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Peptidase_C1 PF00112.18 GAM20190.1 - 2.5e-75 253.1 12.5 4.3e-74 249.0 8.6 2.2 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM20190.1 - 2.9e-15 56.2 3.9 2.9e-15 56.2 2.7 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM20190.1 - 0.00048 18.7 3.3 0.055 11.9 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family RRM_1 PF00076.17 GAM20191.1 - 0.012 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.3 GAM20191.1 - 0.37 9.9 20.8 0.0039 16.4 9.3 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF566 PF04484.7 GAM20191.1 - 6.7 6.1 15.6 0.29 10.5 6.9 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF566) Ank_2 PF12796.2 GAM20192.1 - 3.6e-10 40.0 8.2 6.4e-05 23.2 0.2 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20192.1 - 0.0068 16.5 4.8 14 6.2 0.0 4.8 4 1 2 6 6 6 1 Ankyrin repeat Ank PF00023.25 GAM20192.1 - 0.022 14.5 4.3 7.3 6.5 0.0 4.1 4 1 1 5 5 5 0 Ankyrin repeat Ank_5 PF13857.1 GAM20192.1 - 0.095 12.9 1.0 8.2 6.8 0.0 3.1 3 1 1 4 4 4 0 Ankyrin repeats (many copies) ECH_C PF13766.1 GAM20193.1 - 6.7e-28 97.2 0.1 2.1e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 GAM20193.1 - 7.3e-20 71.1 0.0 2.7e-19 69.2 0.0 1.9 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family FERM_C PF09380.5 GAM20194.1 - 0.057 13.6 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 FERM C-terminal PH-like domain DUF4557 PF15101.1 GAM20195.1 - 0.12 12.2 8.4 0.27 11.0 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CPSF_A PF03178.10 GAM20196.1 - 8.5e-99 330.6 0.1 1.4e-97 326.6 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 GAM20196.1 - 2.1e-67 227.4 0.0 4.6e-67 226.2 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term UQ_con PF00179.21 GAM20197.1 - 2.4e-25 88.5 0.1 2.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COX6B PF02297.12 GAM20198.1 - 0.044 13.7 1.3 0.52 10.3 0.9 2.1 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb PEN-2 PF10251.4 GAM20199.1 - 8.6e-16 57.9 8.2 1.2e-15 57.5 5.7 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DPM3 PF08285.6 GAM20199.1 - 1.5 8.6 6.6 2.1 8.2 4.6 1.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SPT6_acidic PF14632.1 GAM20200.1 - 0.0013 18.8 5.7 0.063 13.4 0.0 2.2 2 0 0 2 2 2 2 Acidic N-terminal SPT6 SpoIIIAH PF12685.2 GAM20200.1 - 0.0081 15.6 6.3 0.0099 15.3 4.4 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF3780 PF12635.2 GAM20200.1 - 0.17 11.3 3.5 5.3 6.5 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3780) Abhydrolase_8 PF06259.7 GAM20200.1 - 0.2 11.1 1.9 0.6 9.5 0.6 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase DUF4358 PF14270.1 GAM20200.1 - 0.25 11.2 3.0 0.2 11.5 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) VGLL4 PF15245.1 GAM20200.1 - 0.29 10.9 7.1 0.16 11.8 3.1 1.6 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 SAGA-Tad1 PF12767.2 GAM20200.1 - 8.4 5.9 9.3 0.64 9.6 2.3 1.8 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit CarboxypepD_reg PF13620.1 GAM20201.1 - 0.00072 19.5 0.0 0.00078 19.4 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF1604 PF07713.8 GAM20201.1 - 0.069 12.9 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Cna_B PF05738.8 GAM20202.1 - 2.5e-14 52.7 16.0 0.00011 21.8 0.5 6.4 5 1 0 5 5 5 5 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM20202.1 - 4e-10 39.6 3.0 1.3 9.1 0.0 5.4 5 0 0 5 5 5 4 Carboxypeptidase regulatory-like domain DUF3244 PF11589.3 GAM20202.1 - 0.00028 20.5 0.1 1.5 8.5 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3244) DUF1604 PF07713.8 GAM20202.1 - 0.0019 17.9 0.5 0.57 10.0 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1604) Y_Y_Y PF07495.8 GAM20202.1 - 0.021 14.5 1.1 0.74 9.6 0.0 3.3 3 0 0 3 3 3 0 Y_Y_Y domain CHU_C PF13585.1 GAM20202.1 - 0.032 14.1 0.6 0.12 12.2 0.4 2.0 1 0 0 1 1 1 0 C-terminal domain of CHU protein family FlgD_ig PF13860.1 GAM20202.1 - 0.19 11.5 1.6 11 5.7 0.0 3.2 3 0 0 3 3 3 0 FlgD Ig-like domain Ycf1 PF05758.7 GAM20203.1 - 0.33 8.5 22.7 0.026 12.2 12.0 1.8 2 0 0 2 2 2 0 Ycf1 LMBR1 PF04791.11 GAM20203.1 - 1.3 7.4 11.6 2.2 6.7 8.1 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein RGS PF00615.14 GAM20205.1 - 2.4e-06 27.6 1.6 0.056 13.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain FAM220 PF15487.1 GAM20205.1 - 0.51 9.6 4.9 0.8 9.0 3.4 1.4 1 0 0 1 1 1 0 FAM220 family Mito_carr PF00153.22 GAM20206.1 - 5.9e-75 247.0 2.1 8.2e-29 99.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Guanylate_cyc PF00211.15 GAM20207.1 - 3.1e-75 251.5 2.1 2.9e-40 137.5 0.3 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.24 GAM20208.1 - 4.7e-06 26.7 0.6 4.7e-06 26.7 0.4 2.5 2 0 0 2 2 2 1 PH domain Auxin_repressed PF05564.7 GAM20208.1 - 0.0026 18.3 1.4 0.0026 18.3 0.9 3.9 2 1 2 4 4 4 1 Dormancy/auxin associated protein Metallophos_2 PF12850.2 GAM20209.1 - 3.1e-20 72.5 0.2 3.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAM20209.1 - 0.0014 18.0 0.2 0.28 10.5 0.0 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PhoPQ_related PF10142.4 GAM20210.1 - 7.4e-59 199.0 0.1 8.7e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein GTP_EFTU PF00009.22 GAM20211.1 - 7.2e-41 139.6 0.0 1.3e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM20211.1 - 1.6e-20 73.1 0.2 3.5e-20 72.0 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM20211.1 - 5.6e-11 42.4 0.2 1.5e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM20211.1 - 1.7e-07 31.1 0.0 7.7e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAM20211.1 - 1.2e-06 28.0 0.1 3.6e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Dynamin_N PF00350.18 GAM20211.1 - 0.00087 19.1 0.0 0.81 9.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.13 GAM20211.1 - 0.012 14.9 0.5 0.52 9.5 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 GAM20211.1 - 0.04 13.4 0.1 5.9 6.5 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM20211.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NmrA PF05368.8 GAM20212.1 - 2.6e-29 102.1 0.1 3.5e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM20212.1 - 2.5e-08 34.1 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM20212.1 - 3.2e-06 26.0 0.0 4.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2487 PF10673.4 GAM20212.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Pox_polyA_pol PF03296.8 GAM20212.1 - 0.099 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain CBS PF00571.23 GAM20214.1 - 6.3e-12 45.0 1.9 2.4e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 CBS domain DUF1487 PF07368.6 GAM20214.1 - 0.002 17.3 0.2 0.0047 16.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) NCD1 PF04904.8 GAM20214.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) SporV_AA PF12164.3 GAM20214.1 - 2.5 8.1 6.1 0.81 9.7 0.6 2.4 2 1 0 2 2 2 0 Stage V sporulation protein AA CBS PF00571.23 GAM20215.1 - 8.5e-07 28.6 0.4 2.1e-06 27.4 0.2 1.7 1 1 0 1 1 1 1 CBS domain FNIP PF05725.7 GAM20216.1 - 3.3e-85 279.8 45.4 1.9e-14 53.3 0.0 11.9 9 2 4 14 14 14 12 FNIP Repeat F-box-like PF12937.2 GAM20216.1 - 0.0039 16.8 0.7 0.014 15.0 0.5 2.0 1 0 0 1 1 1 1 F-box-like DUF2454 PF10521.4 GAM20217.1 - 0.00037 19.5 0.9 0.00037 19.5 0.6 3.3 2 2 0 2 2 2 1 Protein of unknown function (DUF2454) DUF2428 PF10350.4 GAM20217.1 - 0.016 14.2 0.1 0.046 12.7 0.1 1.8 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) FAST_2 PF08368.7 GAM20217.1 - 0.021 15.2 2.2 0.14 12.5 0.1 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Snapin_Pallidin PF14712.1 GAM20217.1 - 0.26 11.6 6.9 0.88 9.9 0.2 3.5 3 0 0 3 3 3 0 Snapin/Pallidin PH PF00169.24 GAM20218.1 - 3e-32 110.9 6.2 3.1e-17 62.6 0.4 2.9 3 0 0 3 3 3 2 PH domain LIM PF00412.17 GAM20218.1 - 1.8e-23 82.3 28.2 5.3e-11 42.4 5.9 3.5 3 0 0 3 3 3 3 LIM domain PH_11 PF15413.1 GAM20218.1 - 1.5e-12 47.7 11.6 1.8e-07 31.3 2.7 4.4 3 2 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 GAM20218.1 - 3.6e-08 33.5 1.7 0.0039 17.3 0.5 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 GAM20218.1 - 4.7e-05 23.3 2.2 5.8e-05 23.0 0.2 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.1 GAM20218.1 - 0.00087 19.1 1.4 0.0017 18.1 0.1 2.2 3 0 0 3 3 3 1 PH domain NUDIX PF00293.23 GAM20219.1 - 2.2e-12 46.7 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3973 PF13119.1 GAM20219.1 - 0.0031 17.4 0.0 0.022 14.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3973) FEZ PF07763.8 GAM20219.1 - 0.064 12.9 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein Ras PF00071.17 GAM20220.1 - 7.9e-42 142.3 0.1 9.2e-42 142.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM20220.1 - 6.3e-21 75.0 0.0 1.3e-20 74.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM20220.1 - 3.9e-13 49.0 0.1 5.1e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM20220.1 - 1.3e-07 30.9 0.0 3e-07 29.8 0.0 1.6 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM20220.1 - 1.5e-05 24.3 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAM20220.1 - 2.1e-05 24.0 0.2 0.00058 19.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM20220.1 - 0.0012 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM20220.1 - 0.0061 16.1 0.2 0.019 14.4 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein G-alpha PF00503.15 GAM20220.1 - 0.077 11.6 0.1 0.85 8.2 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit NDUFA12 PF05071.11 GAM20221.1 - 1.2e-15 57.8 1.2 2.9e-15 56.6 0.8 1.6 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_11 PF13414.1 GAM20222.1 - 7.6e-10 38.3 0.1 0.0018 17.8 0.5 4.2 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 GAM20222.1 - 3.3e-08 32.8 0.1 0.077 12.9 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20222.1 - 8.4e-07 28.3 0.0 0.0061 16.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20222.1 - 1.1e-06 27.9 0.2 0.016 14.9 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20222.1 - 6.9e-06 25.9 0.4 0.00012 21.9 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20222.1 - 0.00024 20.6 0.0 0.1 12.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20222.1 - 0.0036 17.3 0.0 1 9.7 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20222.1 - 0.0067 16.9 0.0 4.9 8.0 0.0 4.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20222.1 - 0.035 14.7 1.7 0.8 10.4 0.0 3.2 1 1 3 4 4 4 0 Tetratricopeptide repeat ODV-E18 PF10717.4 GAM20223.1 - 0.001 18.4 0.0 0.001 18.4 0.0 2.8 3 0 0 3 3 3 1 Occlusion-derived virus envelope protein ODV-E18 Shisa PF13908.1 GAM20223.1 - 0.0033 17.6 4.8 0.0033 17.6 3.3 2.0 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator FAM163 PF15069.1 GAM20223.1 - 0.0055 17.2 1.6 0.021 15.4 0.0 2.1 2 1 0 2 2 2 1 FAM163 family TMEM154 PF15102.1 GAM20223.1 - 0.01 15.5 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family ASFV_J13L PF05568.6 GAM20223.1 - 0.043 13.3 2.0 0.13 11.8 1.3 1.8 1 1 0 1 1 1 0 African swine fever virus J13L protein Mid2 PF04478.7 GAM20223.1 - 0.84 9.0 10.0 0.83 9.0 4.1 2.7 2 1 0 2 2 2 0 Mid2 like cell wall stress sensor RRM_1 PF00076.17 GAM20225.1 - 9.5e-14 50.7 0.0 4.7e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20225.1 - 1.9e-11 43.7 0.0 3.5e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20225.1 - 5.6e-10 38.9 0.2 2.7e-08 33.5 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM20225.1 - 0.00046 19.8 0.1 0.0015 18.2 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 GAM20225.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 GpcrRhopsn4 PF10192.4 GAM20226.1 - 1.3e-09 37.6 13.4 1.3e-09 37.6 9.3 2.9 3 0 0 3 3 3 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 GAM20226.1 - 5.3e-06 25.5 28.8 5.3e-06 25.5 20.0 1.7 2 0 0 2 2 2 1 Lung seven transmembrane receptor Spermine_synth PF01564.12 GAM20227.1 - 8.4e-92 306.5 0.0 1.1e-91 306.1 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 GAM20227.1 - 1.2e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM20227.1 - 0.025 15.1 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 GAM20227.1 - 0.072 13.9 0.0 0.21 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain fn3 PF00041.16 GAM20228.1 - 1.1e-09 38.2 16.3 0.027 14.5 0.1 6.1 6 0 0 6 6 6 4 Fibronectin type III domain DUF1191 PF06697.7 GAM20228.1 - 0.0022 16.8 1.2 0.82 8.4 0.3 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1191) Colipase-like PF15083.1 GAM20228.1 - 0.0082 16.0 1.8 0.024 14.5 1.2 1.7 1 0 0 1 1 1 1 Colipase-like EGF_2 PF07974.8 GAM20228.1 - 0.19 11.9 18.1 0.021 14.9 9.1 2.1 2 0 0 2 2 2 0 EGF-like domain CRAL_TRIO PF00650.15 GAM20229.1 - 1.1e-28 99.7 0.6 1.5e-28 99.2 0.4 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAM20229.1 - 1.1e-07 31.9 0.6 2.3e-07 30.8 0.1 1.9 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain RNA_pol_Rpb1_3 PF04983.13 GAM20229.1 - 0.082 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 ABC1 PF03109.11 GAM20230.1 - 1.2e-35 122.0 0.8 2.3e-35 121.1 0.1 1.9 2 0 0 2 2 2 1 ABC1 family Urocanase PF01175.13 GAM20231.1 - 1.1e-216 720.2 0.9 1.3e-216 719.9 0.6 1.0 1 0 0 1 1 1 1 Urocanase bZIP_1 PF00170.16 GAM20232.1 - 1.2e-05 25.1 15.7 1.2e-05 25.1 10.9 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 GAM20232.1 - 2.2e-05 24.1 17.2 2.2e-05 24.1 11.9 5.8 4 2 1 5 5 5 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM20232.1 - 0.011 16.0 7.0 0.011 16.0 4.8 7.1 5 2 2 7 7 7 0 bZIP Maf transcription factor LRR_4 PF12799.2 GAM20233.1 - 2.5e-29 100.3 57.4 9e-09 34.7 1.2 5.8 2 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM20233.1 - 7e-22 76.9 27.0 5.2e-07 29.3 8.9 4.7 2 2 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 GAM20233.1 - 4.9e-21 71.5 23.1 0.01 15.7 0.0 8.7 9 0 0 9 9 9 7 Leucine Rich Repeat LRR_7 PF13504.1 GAM20233.1 - 4e-13 47.2 27.9 0.56 10.6 0.0 8.6 9 0 0 9 9 9 5 Leucine rich repeat LRR_6 PF13516.1 GAM20233.1 - 5.3e-06 25.9 33.9 1.8 8.8 0.1 8.4 7 1 1 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.1 GAM20233.1 - 0.00023 20.7 2.9 0.33 10.5 0.4 2.3 1 1 0 2 2 2 2 Leucine-rich repeat DUF2322 PF10084.4 GAM20233.1 - 0.0012 18.5 0.1 0.43 10.3 0.0 3.2 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2322) LRRNT PF01462.13 GAM20233.1 - 0.25 10.8 2.9 17 5.0 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain GST_N PF02798.15 GAM20234.1 - 7.1e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM20234.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM20234.1 - 0.00033 21.0 0.0 0.00091 19.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM20234.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM20234.1 - 0.0023 17.7 0.0 0.0087 15.9 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM20234.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.5 GAM20234.1 - 0.054 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain Erf4 PF10256.4 GAM20235.1 - 0.00076 19.3 1.5 0.0088 15.8 1.0 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family 7TM_transglut PF14402.1 GAM20235.1 - 0.0048 15.8 1.9 0.0063 15.4 1.3 1.1 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase Patched PF02460.13 GAM20235.1 - 3.6 5.3 7.3 4.6 5.0 4.7 1.4 1 1 1 2 2 2 0 Patched family Pkinase PF00069.20 GAM20236.1 - 1.3e-68 230.9 0.0 1.5e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20236.1 - 2.2e-27 95.7 0.0 2.8e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M8 PF01457.11 GAM20237.1 - 4.6e-70 236.4 3.8 6.5e-69 232.6 2.6 1.9 1 1 0 1 1 1 1 Leishmanolysin Peptidase_C1 PF00112.18 GAM20238.1 - 1.7e-64 217.7 9.5 2.1e-64 217.4 6.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM20238.1 - 6e-14 52.0 0.6 1.2e-13 51.0 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM20238.1 - 6.7e-05 21.5 0.1 0.17 10.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family NTPase_I-T PF01931.13 GAM20239.1 - 4.2e-53 179.5 0.0 5e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DIE2_ALG10 PF04922.7 GAM20240.1 - 2e-84 283.8 37.2 2.7e-84 283.3 25.8 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family 2OG-FeII_Oxy_2 PF13532.1 GAM20241.1 - 6.7e-29 101.0 0.5 1.3e-28 100.1 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.4 GAM20241.1 - 0.012 15.0 0.6 0.019 14.4 0.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BRO1 PF03097.13 GAM20241.1 - 0.24 10.0 5.3 0.15 10.8 2.3 1.6 2 0 0 2 2 2 0 BRO1-like domain Mito_carr PF00153.22 GAM20242.1 - 5.1e-77 253.6 1.2 1.7e-26 91.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM PF01423.17 GAM20242.1 - 0.12 11.9 0.3 9.5 5.8 0.0 2.2 2 0 0 2 2 2 0 LSM domain SSXT PF05030.7 GAM20243.1 - 5.7e-16 57.8 2.4 5.7e-16 57.8 1.6 2.0 2 0 0 2 2 2 1 SSXT protein (N-terminal region) YmaF PF12788.2 GAM20244.1 - 0.064 13.4 0.2 0.085 13.0 0.1 1.2 1 0 0 1 1 1 0 YmaF family 4F5 PF04419.9 GAM20245.1 - 3e-05 24.6 4.8 3e-05 24.6 3.3 2.3 2 1 0 2 2 2 1 4F5 protein family Macoilin PF09726.4 GAM20245.1 - 2.1 6.5 7.8 1.9 6.6 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein FNIP PF05725.7 GAM20246.1 - 1.2e-06 28.2 6.5 7.3e-05 22.6 0.0 4.4 4 1 0 4 4 4 2 FNIP Repeat TAF8_C PF10406.4 GAM20246.1 - 0.87 9.6 4.7 2.5 8.2 0.4 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term CH PF00307.26 GAM20247.1 - 2.4e-15 56.5 0.0 5.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM20247.1 - 0.00013 21.5 0.0 0.00031 20.3 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain Peptidase_S10 PF00450.17 GAM20248.1 - 1.4e-106 357.1 9.5 1.7e-106 356.8 6.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase XPC-binding PF09280.6 GAM20250.1 - 1.2e-16 59.9 12.6 1.2e-16 59.9 7.5 1.9 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.18 GAM20250.1 - 2.8e-15 55.4 0.4 4.6e-15 54.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 GAM20250.1 - 1.1e-14 53.7 5.1 1.7e-10 40.4 0.1 3.0 3 0 0 3 3 3 2 UBA/TS-N domain Rad60-SLD PF11976.3 GAM20250.1 - 1.4e-06 27.9 0.2 3e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sigma70_ner PF04546.8 GAM20250.1 - 0.0022 17.6 0.1 0.0033 17.0 0.1 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Propep_M14 PF02244.11 GAM20250.1 - 0.013 15.1 0.6 1 9.0 0.0 2.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide MCM_N PF14551.1 GAM20250.1 - 0.036 14.5 0.7 0.15 12.5 0.2 2.2 2 1 0 2 2 2 0 MCM N-terminal domain DnaB_2 PF07261.6 GAM20250.1 - 0.062 12.9 0.3 0.32 10.6 0.1 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment Rad60-SLD_2 PF13881.1 GAM20250.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MGC-24 PF05283.6 GAM20250.1 - 0.92 9.2 7.9 1.6 8.4 5.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) EF_TS PF00889.14 GAM20251.1 - 3.5e-44 150.7 0.3 4.1e-43 147.2 0.2 2.1 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.26 GAM20251.1 - 3e-08 33.2 0.0 9.4e-08 31.6 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.1 GAM20252.1 - 4.7e-27 93.7 4.2 1.9e-10 40.5 0.0 5.1 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20252.1 - 6.7e-10 38.7 2.8 1.2 9.9 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM20252.1 - 1.9e-08 33.7 8.5 0.0029 17.2 0.9 4.4 5 0 0 5 5 5 3 TPR repeat TPR_19 PF14559.1 GAM20252.1 - 6.9e-08 32.7 6.9 0.0002 21.6 0.4 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20252.1 - 1.2e-07 32.2 1.9 0.076 13.7 0.3 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM20252.1 - 1.1e-06 28.2 6.6 1.7 8.6 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20252.1 - 5.4e-05 22.6 6.6 1.6 8.4 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20252.1 - 0.0022 17.7 12.5 11 6.2 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20252.1 - 0.005 16.9 1.1 0.4 11.0 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20252.1 - 0.014 15.1 5.4 26 4.9 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2664 PF10867.3 GAM20252.1 - 0.054 14.1 0.6 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) DUF3366 PF11846.3 GAM20252.1 - 0.088 12.6 0.4 15 5.4 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) RRM_1 PF00076.17 GAM20253.1 - 2.7e-30 103.8 0.1 5.4e-16 57.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20253.1 - 1e-22 79.8 0.0 3.1e-09 36.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20253.1 - 1.4e-13 50.4 0.0 0.0019 18.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 GAM20253.1 - 0.043 13.8 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Spo7_2_N PF15407.1 GAM20253.1 - 0.11 12.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein family 7 RNA_lig_T4_1 PF09511.5 GAM20255.1 - 1.1e-45 155.8 0.4 1.1e-45 155.8 0.3 1.5 2 0 0 2 2 2 1 RNA ligase DUF366 PF04017.7 GAM20255.1 - 0.022 14.0 0.2 0.17 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF366) DUF1902 PF08972.6 GAM20255.1 - 0.13 11.7 0.3 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Ribosomal_L29 PF00831.18 GAM20256.1 - 2.2e-14 52.8 2.3 2.2e-14 52.8 1.6 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein DUF2228 PF10228.4 GAM20256.1 - 0.62 9.5 4.4 0.77 9.2 3.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) CBS PF00571.23 GAM20257.1 - 1.3e-16 60.0 3.8 1.7e-06 27.6 0.2 4.3 4 0 0 4 4 4 4 CBS domain Nop10p PF04135.7 GAM20258.1 - 1.7e-17 62.8 0.5 2e-17 62.6 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ank_2 PF12796.2 GAM20259.1 - 1.4e-34 118.2 4.3 2.9e-11 43.5 0.1 4.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20259.1 - 3.1e-26 91.2 10.9 6.1e-06 26.6 0.1 7.0 4 3 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20259.1 - 2.2e-24 84.9 13.7 0.0064 16.7 0.1 9.5 3 1 7 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20259.1 - 2.6e-24 82.8 7.8 0.021 15.0 0.0 10.2 6 1 4 10 10 10 7 Ankyrin repeat Ank PF00023.25 GAM20259.1 - 2.8e-21 74.1 8.7 0.0043 16.7 0.0 10.1 8 1 3 11 11 11 6 Ankyrin repeat P16-Arc PF04699.9 GAM20260.1 - 4.2e-39 133.9 0.1 4.6e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UTP15_C PF09384.5 GAM20260.1 - 0.036 13.7 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 UTP15 C terminal E2F_TDP PF02319.15 GAM20261.1 - 3.3e-20 71.4 1.3 3.6e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.6 GAM20261.1 - 0.006 16.2 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 2 CDC6, C terminal TrmB PF01978.14 GAM20261.1 - 0.014 15.0 0.3 0.55 9.9 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB CAP_assoc_N PF14504.1 GAM20261.1 - 0.047 13.4 0.1 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 CAP-associated N-terminal DnaJ PF00226.26 GAM20262.1 - 4.5e-25 87.1 1.1 4.5e-25 87.1 0.8 2.6 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 GAM20262.1 - 4.2e-09 36.2 11.3 2.6e-08 33.7 2.7 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 GAM20262.1 - 2.2e-05 24.5 11.1 0.03 14.6 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 GAM20262.1 - 2.6e-05 24.2 3.0 2.6e-05 24.2 2.1 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 GAM20262.1 - 0.00023 21.2 7.7 0.081 13.2 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAM20262.1 - 0.0023 18.0 17.5 0.011 15.7 0.2 3.7 3 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 GAM20262.1 - 0.36 10.7 7.6 0.43 10.5 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger MIP PF00230.15 GAM20263.1 - 1.6e-49 168.4 20.0 4.5e-33 114.6 6.2 2.0 2 0 0 2 2 2 2 Major intrinsic protein CLTH PF10607.4 GAM20264.1 - 3.3e-39 133.8 1.7 4.7e-39 133.3 1.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 GAM20264.1 - 1e-10 40.9 1.0 2.6e-10 39.6 0.2 2.0 2 0 0 2 2 2 1 LisH TINF2_N PF14973.1 GAM20264.1 - 0.06 13.4 2.6 0.083 13.0 0.1 2.3 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus UvrD-helicase PF00580.16 GAM20264.1 - 0.22 10.7 3.6 0.34 10.1 2.5 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain VHP PF02209.14 GAM20265.1 - 4.2e-12 45.5 3.1 1.5e-11 43.7 1.7 2.3 2 0 0 2 2 2 1 Villin headpiece domain UPF0203 PF05254.7 GAM20266.1 - 4.1e-17 61.7 7.9 5.2e-17 61.4 5.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 GAM20266.1 - 0.0084 16.1 2.9 0.028 14.4 2.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 GAM20266.1 - 0.043 13.6 6.6 0.65 9.8 0.2 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 GAM20266.1 - 0.24 11.3 3.0 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 CHCH domain Pkinase_Tyr PF07714.12 GAM20267.1 - 1.9e-69 233.6 0.0 2.4e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM20267.1 - 4.3e-61 206.3 0.0 6.3e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.1 GAM20267.1 - 5.3e-37 125.1 7.3 3.6e-11 42.9 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM20267.1 - 1.7e-31 107.7 12.6 1.6e-11 43.8 0.1 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM20267.1 - 1e-26 92.3 2.7 5.4e-05 23.0 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 GAM20267.1 - 7.9e-20 70.1 7.7 8e-05 22.1 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM20267.1 - 1.8e-19 68.9 8.7 7.1e-06 25.9 0.0 6.4 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAM20267.1 - 5.1e-19 67.2 14.4 3.8e-07 29.5 0.0 6.4 7 0 0 7 7 6 4 Kelch motif Kinase-like PF14531.1 GAM20267.1 - 0.011 14.6 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAM20267.1 - 0.03 13.3 0.1 0.051 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RAG2 PF03089.9 GAM20267.1 - 0.06 12.0 0.5 7.5 5.1 0.0 2.5 2 1 1 3 3 3 0 Recombination activating protein 2 APH PF01636.18 GAM20267.1 - 0.17 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Orthopox_C10L PF07020.6 GAM20268.1 - 0.012 16.1 5.0 0.012 16.1 3.5 2.8 3 0 0 3 3 3 0 Orthopoxvirus C10L protein F-protein PF00469.15 GAM20268.1 - 1.6 8.0 3.9 0.57 9.5 0.4 1.8 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Sds3 PF08598.6 GAM20269.1 - 1.7e-20 73.4 22.5 1.7e-20 73.4 15.6 5.9 2 2 0 2 2 2 1 Sds3-like Homeobox PF00046.24 GAM20270.1 - 1.7e-19 69.1 4.4 3.2e-19 68.3 3.1 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAM20270.1 - 0.0014 18.2 0.2 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain DUF1524 PF07510.6 GAM20270.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) tRNA-synt_1g PF09334.6 GAM20271.1 - 5e-144 479.7 0.0 6.4e-144 479.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.15 GAM20271.1 - 3.4e-20 71.6 0.8 6.2e-20 70.8 0.5 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.17 GAM20271.1 - 3.6e-09 35.1 0.9 0.0055 14.7 0.0 3.8 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM20271.1 - 1.6e-07 31.2 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA COG6 PF06419.6 GAM20271.1 - 0.032 12.3 0.0 0.09 10.8 0.0 1.7 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 DZR PF12773.2 GAM20271.1 - 3.7 7.4 8.0 34 4.3 5.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon Alpha_L_fucos PF01120.12 GAM20272.1 - 2.4e-114 381.8 3.8 3e-114 381.5 2.6 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Arf PF00025.16 GAM20273.1 - 1.2e-48 164.6 0.0 1.4e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAM20273.1 - 7.5e-14 51.2 1.5 3.2e-10 39.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 GAM20273.1 - 2.9e-10 40.6 0.0 4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM20273.1 - 4e-09 36.0 0.0 5.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM20273.1 - 5e-09 35.6 0.0 5.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM20273.1 - 1.8e-08 33.8 0.0 2.3e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM20273.1 - 2.5e-05 24.1 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM20273.1 - 3.5e-05 23.3 0.4 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAM20273.1 - 0.00041 20.4 0.4 0.0068 16.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 GAM20273.1 - 0.0031 16.9 2.4 0.21 11.0 0.2 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 GAM20273.1 - 0.0046 16.9 0.4 0.022 14.7 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAM20273.1 - 0.0068 17.2 0.3 0.013 16.3 0.2 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAM20273.1 - 0.0082 16.4 0.8 0.011 15.9 0.5 1.6 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 GAM20273.1 - 0.0082 15.8 1.3 0.12 12.0 0.9 2.3 1 1 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.12 GAM20273.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.1 GAM20273.1 - 0.018 15.3 0.6 0.037 14.3 0.4 1.6 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 GAM20273.1 - 0.038 12.7 0.3 8.2 5.1 0.0 2.7 2 1 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 GAM20273.1 - 0.055 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 GAM20273.1 - 0.071 12.7 0.3 0.3 10.7 0.1 1.8 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 GAM20273.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 GAM20273.1 - 0.13 12.6 0.3 0.22 11.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 GAM20273.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Acyl-CoA_dh_M PF02770.14 GAM20274.1 - 1.5e-08 33.9 0.0 3.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM20274.1 - 6.5e-08 32.8 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 GAM20274.1 - 7.7e-06 25.4 0.0 1.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 GAM20274.1 - 0.0035 17.6 0.0 0.008 16.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal G-alpha PF00503.15 GAM20275.1 - 1.5e-115 386.0 6.0 1.8e-115 385.7 4.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM20275.1 - 1.1e-14 54.0 0.6 5.8e-11 41.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM20275.1 - 0.0017 17.5 1.3 0.83 8.7 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 GAM20275.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM20275.1 - 0.039 13.9 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF2985 PF11204.3 GAM20275.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Microtub_assoc PF07989.6 GAM20276.1 - 1.4e-07 31.2 5.8 1.4e-07 31.2 4.0 7.8 5 3 3 8 8 8 2 Microtubule associated SET PF00856.23 GAM20277.1 - 3.9e-16 59.7 0.1 8.4e-15 55.4 0.1 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 GAM20277.1 - 7.5e-09 35.1 5.8 0.0011 18.5 0.2 3.6 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 GAM20277.1 - 0.00014 21.7 5.5 0.1 12.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20277.1 - 0.0016 18.2 0.2 3.9 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20277.1 - 0.024 14.2 0.0 0.024 14.2 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20277.1 - 0.1 12.4 2.6 4.4 7.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MUG113 PF13455.1 GAM20277.1 - 0.18 12.2 2.9 25 5.3 0.0 3.6 3 1 1 4 4 4 0 Meiotically up-regulated gene 113 tRNA-synt_1b PF00579.20 GAM20278.1 - 3.4e-69 233.1 0.6 5e-69 232.6 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribonuc_2-5A PF06479.7 GAM20278.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Methyltransf_27 PF13708.1 GAM20278.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NIF PF03031.13 GAM20279.1 - 1.2e-52 177.8 0.5 2.9e-52 176.5 0.4 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Med15 PF09606.5 GAM20279.1 - 1.3 7.1 45.0 2 6.5 31.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Synaptobrevin PF00957.16 GAM20280.1 - 9.9e-27 92.3 5.8 1.1e-26 92.1 4.0 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 GAM20280.1 - 0.0037 17.2 3.0 0.0037 17.2 2.1 1.8 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 GAM20280.1 - 0.0051 16.4 0.9 0.0053 16.4 0.6 1.1 1 0 0 1 1 1 1 Rifin/stevor family DUF2207 PF09972.4 GAM20280.1 - 0.012 14.2 0.6 0.013 14.1 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3675 PF12428.3 GAM20280.1 - 0.016 15.4 0.8 0.021 15.0 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) Fusion_gly PF00523.13 GAM20280.1 - 0.025 12.6 2.4 0.029 12.4 1.6 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 TMCO5 PF14992.1 GAM20280.1 - 0.03 13.4 1.1 0.035 13.2 0.8 1.1 1 0 0 1 1 1 0 TMCO5 family SLD3 PF08639.5 GAM20280.1 - 0.044 12.4 2.6 0.054 12.1 1.8 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Sec5 PF15469.1 GAM20280.1 - 0.049 13.3 2.4 0.057 13.1 1.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 Pex24p PF06398.6 GAM20280.1 - 0.06 12.1 1.0 0.067 11.9 0.7 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ATP-synt_S1 PF05827.7 GAM20280.1 - 0.065 12.5 0.3 0.075 12.3 0.2 1.0 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Rhabdo_glycop PF00974.13 GAM20280.1 - 0.14 10.3 1.0 0.15 10.2 0.7 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein UPF0258 PF06789.7 GAM20280.1 - 1 9.3 3.5 1.1 9.3 1.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) Ibs_toxin PF13956.1 GAM20280.1 - 3.8 7.4 11.0 15 5.5 7.6 2.0 1 1 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Acyltransferase PF01553.16 GAM20281.1 - 2.3e-16 59.4 0.1 4e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase PROCT PF08084.6 GAM20281.1 - 0.023 14.4 0.7 1.1 8.9 0.0 2.9 3 0 0 3 3 3 0 PROCT (NUC072) domain Rad51 PF08423.6 GAM20282.1 - 1.7e-05 23.8 0.2 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 GAM20282.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 GAM20282.1 - 0.002 17.2 0.0 0.0069 15.4 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_35 PF14516.1 GAM20282.1 - 0.0087 14.7 0.2 0.013 14.1 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain Arch_ATPase PF01637.13 GAM20282.1 - 0.0096 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 GAM20282.1 - 0.086 12.7 0.3 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 GAM20282.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PA14 PF07691.7 GAM20283.1 - 0.0042 16.7 0.0 0.0097 15.5 0.0 1.6 1 1 0 1 1 1 1 PA14 domain PDT PF00800.13 GAM20283.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydratase FNIP PF05725.7 GAM20284.1 - 1.7e-46 155.8 34.2 1.6e-13 50.3 0.1 7.5 4 1 5 9 9 9 9 FNIP Repeat FNIP PF05725.7 GAM20285.1 - 9.2e-43 143.9 22.7 3.8e-12 45.9 0.6 7.3 6 1 1 7 7 7 6 FNIP Repeat DUF4499 PF14934.1 GAM20285.1 - 0.13 12.2 0.1 0.47 10.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Glyco_hydro_85 PF03644.8 GAM20286.1 - 3.2e-91 305.7 1.2 4.4e-91 305.2 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 FBA PF04300.8 GAM20286.1 - 3.4e-14 53.2 0.0 7.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 F-box associated region Glyco_hydro_18 PF00704.23 GAM20286.1 - 0.00017 21.1 0.0 0.00028 20.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 FNIP PF05725.7 GAM20287.1 - 9.4e-67 220.7 42.7 4.1e-13 49.0 1.9 7.3 5 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 GAM20287.1 - 3.2e-05 23.7 2.5 1.7 8.6 0.0 4.8 2 2 3 5 5 5 2 Protein of unknown function (DUF1769) EmrE PF13536.1 GAM20288.1 - 0.00015 21.9 6.0 0.00015 21.9 4.2 2.0 1 1 1 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 GAM20288.1 - 0.00053 20.0 12.9 0.0085 16.1 9.8 2.1 1 1 1 2 2 2 1 EamA-like transporter family DUF1632 PF07857.7 GAM20288.1 - 0.0035 16.6 0.6 0.006 15.8 0.4 1.4 1 0 0 1 1 1 1 CEO family (DUF1632) UPF0546 PF10639.4 GAM20288.1 - 0.0082 15.9 0.5 0.0082 15.9 0.3 2.0 1 1 2 3 3 3 1 Uncharacterised protein family UPF0546 DUF4064 PF13273.1 GAM20288.1 - 0.011 15.7 2.4 0.024 14.7 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF543 PF04418.7 GAM20288.1 - 0.015 15.2 1.3 0.21 11.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Thia_YuaJ PF09515.5 GAM20288.1 - 0.02 14.6 5.7 0.036 13.8 3.9 1.5 1 1 1 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) TPT PF03151.11 GAM20288.1 - 0.2 11.3 8.8 3.5 7.2 5.2 2.1 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF2721 PF11026.3 GAM20288.1 - 2.3 7.8 10.0 9 5.9 2.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Ribosomal_S6e PF01092.14 GAM20289.1 - 3.5e-53 178.5 0.1 6.6e-53 177.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e FAM220 PF15487.1 GAM20289.1 - 0.12 11.7 6.0 0.16 11.3 4.2 1.2 1 0 0 1 1 1 0 FAM220 family Sybindin PF04099.7 GAM20290.1 - 9.4e-48 161.5 0.4 1e-47 161.4 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAM20290.1 - 1.9e-08 34.2 0.1 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region GTP_EFTU PF00009.22 GAM20291.1 - 8.3e-31 106.8 0.3 8.3e-31 106.8 0.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAM20291.1 - 1.4e-13 50.6 0.8 4.5e-13 49.0 0.6 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAM20291.1 - 9.8e-08 32.0 0.5 9.8e-08 32.0 0.4 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM20291.1 - 1.3e-07 31.6 0.0 4.9e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM20291.1 - 1.4e-05 25.5 0.0 0.00014 22.2 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 GAM20291.1 - 0.00037 20.1 0.1 0.0013 18.3 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 GAM20291.1 - 0.0008 19.0 0.2 0.003 17.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.1 GAM20291.1 - 0.0016 18.5 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM20291.1 - 0.014 14.5 0.2 0.044 12.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 GAM20291.1 - 0.015 14.6 0.2 0.088 12.0 0.1 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B rve_2 PF13333.1 GAM20292.1 - 0.15 12.1 1.1 0.23 11.5 0.7 1.3 1 1 0 1 1 1 0 Integrase core domain Coiled PF05710.7 GAM20292.1 - 0.39 11.2 5.4 0.41 11.1 2.4 1.8 1 1 0 1 1 1 0 Coiled coil GTP_EFTU PF00009.22 GAM20293.1 - 2.4e-40 137.9 0.0 3.9e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM20293.1 - 5.1e-24 84.1 0.0 9.9e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM20293.1 - 7.1e-20 70.6 0.0 1.8e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM20293.1 - 3.5e-08 33.4 0.1 7.6e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAM20293.1 - 4.6e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 GAM20293.1 - 1.6e-05 24.8 0.0 4.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM20293.1 - 0.00028 21.3 0.0 0.00058 20.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 GAM20293.1 - 0.058 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin Actin PF00022.14 GAM20294.1 - 7e-163 541.6 0.0 7.9e-163 541.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM20294.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CWC25 PF12542.3 GAM20296.1 - 2.3e-10 40.7 3.5 2.3e-10 40.7 2.5 5.1 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 GAM20296.1 - 4e-09 36.3 11.6 4e-09 36.3 8.1 5.5 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF848 PF05852.6 GAM20297.1 - 0.3 10.9 22.2 0.4 10.5 1.9 3.8 3 1 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) ACCA PF03255.9 GAM20297.1 - 1.9 8.0 9.9 4.4 6.8 1.6 2.9 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PRK PF00485.13 GAM20298.1 - 2.9e-24 85.7 0.4 1.1e-23 83.8 0.3 1.9 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.16 GAM20298.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 CYTH domain AAA_17 PF13207.1 GAM20298.1 - 2.5e-05 25.0 0.1 7.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM20298.1 - 0.00016 21.5 0.3 0.0028 17.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM20298.1 - 0.0002 21.6 0.1 0.001 19.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAM20298.1 - 0.00051 19.6 0.5 0.00093 18.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 GAM20298.1 - 0.0016 17.5 0.0 0.005 15.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 GAM20298.1 - 0.0033 17.1 0.5 0.13 11.9 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAM20298.1 - 0.0069 16.1 0.1 0.096 12.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 GAM20298.1 - 0.013 15.7 0.0 0.38 10.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM20298.1 - 0.016 15.1 0.0 0.056 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 GAM20298.1 - 0.021 13.7 0.1 0.042 12.7 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 GAM20298.1 - 0.035 13.8 0.4 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 GAM20298.1 - 0.036 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 GAM20298.1 - 0.04 13.5 2.0 0.1 12.2 0.0 2.4 3 0 0 3 3 3 0 NACHT domain Pex14_N PF04695.8 GAM20298.1 - 0.044 13.8 3.6 0.82 9.7 1.8 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_22 PF13401.1 GAM20298.1 - 0.063 13.4 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM20298.1 - 0.074 13.3 1.5 0.18 12.1 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 GAM20298.1 - 0.081 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI BESS PF02944.15 GAM20299.1 - 0.07 12.6 3.4 0.98 9.0 0.0 2.5 2 0 0 2 2 2 0 BESS motif DUF3439 PF11921.3 GAM20299.1 - 0.23 11.2 7.9 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM20299.1 - 1.6 8.4 19.7 0.75 9.5 3.9 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein PH PF00169.24 GAM20300.1 - 6.7e-15 55.1 0.3 1.4e-14 54.0 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM20300.1 - 3e-05 23.9 0.1 4.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 GAM20300.1 - 9.4e-05 22.6 2.4 0.0029 17.8 0.6 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 GAM20300.1 - 0.0078 16.3 0.1 0.018 15.1 0.1 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain SR-25 PF10500.4 GAM20300.1 - 1.7 8.0 8.2 2.6 7.4 0.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dicty_CAR PF05462.6 GAM20301.1 - 2.3e-08 33.3 20.5 2.3e-08 33.3 14.2 1.9 2 1 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 GAM20301.1 - 2.5e-07 30.1 17.1 4.8e-07 29.1 11.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.19 GAM20301.1 - 9.7e-06 24.8 13.8 9.7e-06 24.8 9.5 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3_C PF11970.3 GAM20301.1 - 0.44 10.3 8.5 0.1 12.3 1.3 2.7 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Cna_B PF05738.8 GAM20302.1 - 6.2e-08 32.2 2.6 2.4e-05 24.0 0.3 4.3 4 1 1 5 5 5 1 Cna protein B-type domain DUF1416 PF07210.7 GAM20302.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) DUF3244 PF11589.3 GAM20302.1 - 0.025 14.2 0.0 9.4 5.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) DUF2012 PF09430.5 GAM20302.1 - 0.028 14.2 0.0 6.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2012) DUF702 PF05142.7 GAM20302.1 - 0.064 13.4 0.5 0.16 12.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Lactonase PF10282.4 GAM20303.1 - 1.2e-100 337.0 0.0 1.3e-100 336.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 GAM20303.1 - 6.3e-05 22.4 0.0 13 5.0 0.0 4.6 2 2 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 GAM20303.1 - 0.0013 18.6 0.0 8 6.5 0.0 3.9 4 0 0 4 4 4 1 Arylesterase SBBP PF06739.6 GAM20303.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat Myotub-related PF06602.9 GAM20304.1 - 6.8e-119 396.7 0.1 6.8e-119 396.7 0.0 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAM20304.1 - 0.0034 17.6 0.0 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family GRAM PF02893.15 GAM20304.1 - 0.0046 16.4 0.0 0.015 14.7 0.0 1.9 1 0 0 1 1 1 1 GRAM domain PH PF00169.24 GAM20304.1 - 0.019 15.1 0.2 0.019 15.1 0.1 2.8 3 2 0 3 3 3 0 PH domain DUF164 PF02591.10 GAM20304.1 - 0.025 14.4 1.0 0.025 14.4 0.7 1.9 2 0 0 2 2 2 0 Putative zinc ribbon domain FYVE PF01363.16 GAM20304.1 - 0.04 13.8 5.6 0.035 13.9 2.1 2.2 2 0 0 2 2 2 0 FYVE zinc finger C1_4 PF07975.7 GAM20304.1 - 1.8 8.6 8.7 0.29 11.1 0.9 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain Thg1 PF04446.7 GAM20305.1 - 5.2e-40 136.1 0.1 7.1e-40 135.7 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 GAM20305.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Thg1 C terminal domain Oxysterol_BP PF01237.13 GAM20306.1 - 1.9e-58 197.6 5.4 3e-58 197.0 3.7 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein DMAP_binding PF06464.6 GAM20306.1 - 0.029 14.9 0.0 0.076 13.6 0.0 1.7 1 0 0 1 1 1 0 DMAP1-binding Domain Proteasome PF00227.21 GAM20308.1 - 7.8e-25 87.2 0.1 1.3e-24 86.4 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Ribosomal_L29 PF00831.18 GAM20309.1 - 0.047 13.3 0.2 0.16 11.6 0.1 1.9 1 0 0 1 1 1 0 Ribosomal L29 protein tRNA-synt_1f PF01921.13 GAM20310.1 - 0.11 11.1 0.8 0.14 10.8 0.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF3133 PF11331.3 GAM20310.1 - 1.2 8.7 5.7 1.9 8.1 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) RAI1 PF08652.6 GAM20311.1 - 1e-19 70.0 0.0 2.9e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IgG_binding_B PF01378.12 GAM20311.1 - 0.13 12.0 4.1 1.7 8.5 3.3 2.3 2 0 0 2 2 2 0 B domain DUF544 PF04424.8 GAM20312.1 - 9.5e-26 89.9 0.1 1.9e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Hormone_3 PF00159.13 GAM20312.1 - 0.0033 17.3 1.4 0.014 15.3 0.5 2.2 2 0 0 2 2 2 1 Pancreatic hormone peptide NTF2 PF02136.15 GAM20313.1 - 5e-18 65.5 0.2 6e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 GAM20313.1 - 0.0036 17.0 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Minor_capsid_1 PF10665.4 GAM20313.1 - 0.042 13.6 0.3 0.075 12.8 0.2 1.3 1 0 0 1 1 1 0 Minor capsid protein DAP_epimerase PF01678.14 GAM20314.1 - 4.9e-48 162.0 0.1 3.8e-26 91.3 0.0 2.5 2 1 0 2 2 2 2 Diaminopimelate epimerase MEA1 PF06910.6 GAM20315.1 - 0.063 12.9 0.2 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Actin PF00022.14 GAM20316.1 - 7.1e-89 297.9 0.0 1e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 Actin PH_3 PF14593.1 GAM20316.1 - 0.07 13.0 0.3 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 PH domain MreB_Mbl PF06723.8 GAM20316.1 - 0.09 11.3 0.0 5.1 5.6 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein GTP_EFTU PF00009.22 GAM20318.1 - 8.7e-48 162.2 0.1 2.8e-47 160.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM20318.1 - 1.8e-20 72.9 0.0 4.9e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 GAM20318.1 - 1.6e-06 27.6 0.3 3e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 GAM20318.1 - 7.3e-06 25.9 0.0 0.0044 16.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase HBS1_N PF08938.5 GAM20318.1 - 4e-05 23.6 7.5 8.6e-05 22.5 5.2 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 GAM20318.1 - 0.00014 21.9 0.3 0.00031 20.7 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 T2SE PF00437.15 GAM20318.1 - 0.0021 17.0 0.2 0.0037 16.1 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Mem_trans PF03547.13 GAM20318.1 - 1.7 6.8 7.3 6.7 4.8 2.0 2.2 2 0 0 2 2 2 0 Membrane transport protein RP-C_C PF11800.3 GAM20318.1 - 7.1 6.2 13.9 0.04 13.6 1.8 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region WW PF00397.21 GAM20319.1 - 4.2e-11 42.4 1.8 8e-11 41.5 1.3 1.5 1 0 0 1 1 1 1 WW domain C2 PF00168.25 GAM20319.1 - 1.8e-09 37.3 0.3 5.2e-09 35.8 0.1 1.8 2 0 0 2 2 2 1 C2 domain DUF605 PF04652.11 GAM20319.1 - 0.054 12.8 24.9 0.078 12.3 17.3 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 GAM20319.1 - 2.4 6.2 40.0 3.3 5.8 27.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Coiled PF05710.7 GAM20320.1 - 1e-10 41.9 11.9 1.3e-10 41.5 8.2 1.2 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.7 GAM20321.1 - 1.5e-11 44.5 11.2 1.8e-11 44.3 7.8 1.1 1 0 0 1 1 1 1 Coiled coil ATP-synt_DE_N PF02823.11 GAM20322.1 - 3.2e-20 71.6 0.0 4.7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain CLASP_N PF12348.3 GAM20323.1 - 9.3e-23 80.7 25.9 8.7e-08 31.7 1.3 7.0 6 1 1 7 7 7 4 CLASP N terminal HEAT PF02985.17 GAM20323.1 - 7.5e-17 59.8 25.0 0.0015 18.4 0.4 11.7 14 0 0 14 14 14 5 HEAT repeat HEAT_2 PF13646.1 GAM20323.1 - 1.2e-11 44.7 20.9 0.16 12.2 0.1 9.9 7 1 2 10 10 10 5 HEAT repeats LON PF02190.11 GAM20323.1 - 0.00089 18.9 0.1 0.044 13.4 0.0 3.5 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain Cnd1 PF12717.2 GAM20323.1 - 0.0024 17.7 17.7 0.021 14.6 0.0 7.4 8 1 0 9 9 9 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 GAM20323.1 - 0.0064 16.9 23.3 0.042 14.3 0.2 8.1 9 0 0 9 9 9 1 HEAT-like repeat DUF2435 PF10363.4 GAM20323.1 - 0.069 13.0 3.7 3.6 7.5 0.1 4.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2435) HATPase_c PF02518.21 GAM20324.1 - 2.1e-26 91.8 0.0 6.9e-26 90.1 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM20324.1 - 1e-19 70.5 0.0 2.9e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM20324.1 - 4.4e-14 52.2 0.0 1e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 GAM20324.1 - 2.2e-05 24.1 0.0 5.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.1 GAM20324.1 - 0.0019 18.5 0.1 0.0069 16.7 0.1 2.0 1 0 0 1 1 1 1 PAS domain Borrelia_orfX PF04160.7 GAM20324.1 - 0.0056 16.5 6.6 0.014 15.2 4.6 1.6 1 0 0 1 1 1 1 Orf-X protein Ank_2 PF12796.2 GAM20325.1 - 8.8e-33 112.5 12.7 2.5e-09 37.3 0.4 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20325.1 - 2.4e-19 69.3 4.3 3.2e-06 27.5 0.0 5.4 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20325.1 - 3e-19 68.5 5.4 0.00077 19.6 0.0 7.4 3 3 4 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20325.1 - 4.6e-18 63.5 3.1 0.13 12.5 0.0 7.3 6 1 1 7 7 7 6 Ankyrin repeat Ank PF00023.25 GAM20325.1 - 8.4e-17 60.0 5.5 0.47 10.3 0.0 7.3 6 1 1 7 7 7 7 Ankyrin repeat DUF3447 PF11929.3 GAM20325.1 - 0.017 14.9 0.0 0.41 10.4 0.0 3.0 1 1 3 4 4 4 0 Domain of unknown function (DUF3447) GTP1_OBG PF01018.17 GAM20326.1 - 2.5e-44 150.6 4.3 7.1e-30 103.7 2.3 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 GAM20326.1 - 2e-19 69.6 0.0 6.5e-19 68.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM20326.1 - 3.7e-05 23.0 0.0 0.00091 18.5 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM20326.1 - 0.029 13.8 0.4 4.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAM20326.1 - 0.12 11.0 0.0 0.38 9.4 0.0 1.7 2 0 0 2 2 2 0 ArgK protein Dynein_light PF01221.13 GAM20327.1 - 1.1e-33 115.0 3.9 1.2e-33 114.9 2.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 GAM20327.1 - 0.0023 18.2 0.7 0.0025 18.0 0.5 1.1 1 0 0 1 1 1 1 Ground-like domain MMgT PF10270.4 GAM20328.1 - 2.9e-22 79.0 0.2 3.3e-22 78.9 0.1 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter DUF996 PF06195.8 GAM20328.1 - 0.077 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF996) RRM_1 PF00076.17 GAM20329.1 - 4.1e-20 71.1 0.0 1.6e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20329.1 - 5.4e-10 39.1 0.1 6.4e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.23 GAM20330.1 - 1.2e-16 59.4 0.4 7.7e-07 28.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM20330.1 - 3.1e-15 55.5 2.9 1.8e-11 43.4 0.4 2.9 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM20330.1 - 1.9e-14 52.3 0.7 0.00097 18.8 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20330.1 - 6.5e-08 32.4 2.7 7.4e-06 25.8 0.3 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20330.1 - 4.4e-05 22.9 0.1 0.059 13.1 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20330.1 - 6.3e-05 22.4 0.9 5.6 7.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20330.1 - 0.00068 20.0 0.5 0.19 12.4 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20330.1 - 0.0089 16.6 0.8 5 7.9 0.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM20330.1 - 0.018 15.4 1.2 1.8 9.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAM20330.1 - 0.044 12.8 0.4 0.46 9.4 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 GAM20330.1 - 0.064 13.1 1.3 0.31 10.9 0.0 2.5 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 GAM20330.1 - 0.072 12.9 0.2 0.17 11.7 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20330.1 - 0.14 12.5 0.5 9.7 6.6 0.5 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.21 GAM20331.1 - 4.7e-51 172.7 0.6 5.7e-51 172.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 GAM20331.1 - 3.6e-06 26.1 0.1 3.6e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Proteasome beta subunits C terminal PIG-L PF02585.12 GAM20332.1 - 7.6e-25 87.8 0.0 2.4e-24 86.2 0.0 1.9 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.15 GAM20332.1 - 3.1e-18 66.2 0.0 5.6e-17 62.1 0.0 2.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ELO PF01151.13 GAM20333.1 - 0.043 13.1 0.3 0.13 11.5 0.1 1.7 1 1 1 2 2 2 0 GNS1/SUR4 family Claudin_2 PF13903.1 GAM20333.1 - 0.093 12.4 7.5 0.51 10.0 5.2 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Viral_Beta_CD PF04530.7 GAM20333.1 - 2 8.6 3.8 1.3 9.2 0.2 2.3 3 0 0 3 3 3 0 Viral Beta C/D like family Trp_oprn_chp PF09534.5 GAM20333.1 - 2.1 7.9 7.2 2.7e+02 1.0 5.0 2.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3325 PF11804.3 GAM20333.1 - 7.6 6.5 10.4 0.34 10.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3325) DUF2417 PF10329.4 GAM20333.1 - 8.3 5.7 8.5 0.32 10.3 1.7 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Amastin PF07344.6 GAM20334.1 - 0.0062 16.1 7.4 0.0091 15.6 4.6 1.7 1 1 0 1 1 1 1 Amastin surface glycoprotein Notch PF00066.12 GAM20334.1 - 0.055 13.7 0.4 0.09 13.0 0.3 1.3 1 0 0 1 1 1 0 LNR domain RDD PF06271.7 GAM20334.1 - 0.084 12.7 4.2 0.15 11.9 2.9 1.4 1 0 0 1 1 1 0 RDD family Endomucin PF07010.7 GAM20334.1 - 0.2 10.9 0.2 1.3 8.3 0.1 1.9 2 0 0 2 2 2 0 Endomucin DUF1625 PF07787.7 GAM20334.1 - 0.31 10.2 2.8 0.47 9.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) HMG_box PF00505.14 GAM20335.1 - 1.2e-18 67.0 1.8 1.2e-18 67.0 1.3 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM20335.1 - 4.6e-13 49.3 1.3 4.6e-13 49.3 0.9 1.7 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.7 GAM20335.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1014 PF06244.7 GAM20335.1 - 0.036 14.2 1.8 0.036 14.2 1.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1014) DUF2582 PF10771.4 GAM20335.1 - 0.055 13.3 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) SR-25 PF10500.4 GAM20335.1 - 0.15 11.5 16.8 0.48 9.8 5.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein YABBY PF04690.8 GAM20335.1 - 1.2 9.2 8.9 0.1 12.8 1.9 1.8 1 1 1 2 2 2 0 YABBY protein DUF755 PF05501.6 GAM20335.1 - 8.3 6.4 18.8 0.36 10.8 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PNPOx_C PF10590.4 GAM20336.1 - 0.0065 15.9 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region RRM_1 PF00076.17 GAM20338.1 - 1.1e-35 121.1 1.2 1.4e-19 69.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20338.1 - 4.3e-28 97.0 0.3 3.3e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20338.1 - 9.3e-16 57.4 0.1 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dicty_REP PF05086.7 GAM20338.1 - 0.0043 14.9 5.3 0.0055 14.5 3.6 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Med3 PF11593.3 GAM20338.1 - 1.9 7.6 15.1 2.3 7.3 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PseudoU_synth_1 PF01416.15 GAM20339.1 - 7.4e-16 58.4 0.0 1.6e-07 31.7 0.0 3.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase Thiolase_N PF00108.18 GAM20340.1 - 4.5e-94 314.3 0.1 7.8e-94 313.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM20340.1 - 9.6e-44 147.7 0.2 1.7e-43 146.9 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM20340.1 - 0.00036 20.0 0.1 0.00072 19.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 GAM20340.1 - 0.099 12.6 0.1 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Histone PF00125.19 GAM20341.1 - 1.5e-13 50.6 0.1 2e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM20341.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Methyltransf_11 PF08241.7 GAM20342.1 - 5e-24 84.6 0.1 4.8e-23 81.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM20342.1 - 1.3e-21 76.7 0.1 4.4e-21 75.0 0.0 2.0 2 2 1 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM20342.1 - 1.5e-20 73.5 0.0 3.1e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM20342.1 - 1.4e-15 57.1 0.0 6e-15 54.9 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM20342.1 - 9e-15 55.2 0.0 4.6e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM20342.1 - 1.8e-13 50.7 0.1 2.2e-12 47.2 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM20342.1 - 3.9e-13 49.6 0.1 1.6e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 GAM20342.1 - 8e-13 48.0 0.1 2.6e-12 46.3 0.0 1.9 3 0 0 3 3 3 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 GAM20342.1 - 7.6e-12 45.2 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polyketide_cyc2 PF10604.4 GAM20342.1 - 8.6e-07 29.2 0.1 2e-06 28.0 0.1 1.6 2 0 0 2 2 1 1 Polyketide cyclase / dehydrase and lipid transport MTS PF05175.9 GAM20342.1 - 1e-05 25.0 0.0 2.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain COXG PF06240.8 GAM20342.1 - 8.7e-05 22.2 0.1 0.00015 21.4 0.1 1.4 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) MetW PF07021.7 GAM20342.1 - 0.00014 21.3 0.1 0.00042 19.7 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 GAM20342.1 - 0.00014 21.4 0.0 0.00043 19.8 0.0 1.8 2 0 0 2 2 1 1 RNA cap guanine-N2 methyltransferase DOT1 PF08123.8 GAM20342.1 - 0.00037 19.8 0.7 0.0032 16.7 0.0 2.4 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 GAM20342.1 - 0.00095 18.8 0.1 0.004 16.8 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain PCMT PF01135.14 GAM20342.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 GAM20342.1 - 0.0025 17.4 0.0 0.014 14.9 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 GAM20342.1 - 0.0043 16.1 0.0 0.079 11.9 0.0 2.5 2 1 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.13 GAM20342.1 - 0.0055 16.3 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 GAM20342.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Polyketide_cyc PF03364.15 GAM20342.1 - 0.033 14.1 0.1 0.09 12.7 0.1 1.8 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Cro PF09048.5 GAM20342.1 - 0.043 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Cro TehB PF03848.9 GAM20342.1 - 0.18 10.9 1.8 0.38 9.8 0.0 2.3 3 0 0 3 3 3 0 Tellurite resistance protein TehB PPV_E2_C PF00511.12 GAM20342.1 - 7.7 6.5 7.1 11 6.0 1.2 2.8 1 1 0 2 2 2 0 E2 (early) protein, C terminal Endosulfine PF04667.12 GAM20343.1 - 0.00015 21.6 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region S1 PF00575.18 GAM20344.1 - 1.4e-15 57.0 14.3 1.6e-07 31.2 0.0 6.6 7 1 0 7 7 7 3 S1 RNA binding domain CENP-T PF15511.1 GAM20344.1 - 4.3 6.4 31.3 2 7.5 7.5 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T TraQ PF09679.5 GAM20345.1 - 0.04 13.8 1.1 0.098 12.5 0.0 2.1 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DUF1129 PF06570.6 GAM20345.1 - 0.053 12.8 10.3 0.01 15.1 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF202 PF02656.10 GAM20345.1 - 2.1 8.6 11.3 9.4 6.5 0.1 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF202) TPR_11 PF13414.1 GAM20346.1 - 1e-08 34.7 5.5 5.1e-06 26.0 1.1 3.2 1 1 1 2 2 2 2 TPR repeat MIT PF04212.13 GAM20346.1 - 6.2e-05 22.7 1.8 0.055 13.3 0.3 2.7 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 GAM20346.1 - 6.4e-05 22.5 3.0 0.2 11.6 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20346.1 - 0.00021 20.7 6.1 0.66 9.6 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM20346.1 - 0.0003 20.6 0.1 0.00063 19.5 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 GAM20346.1 - 0.0041 17.2 2.1 0.0092 16.0 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 GAM20346.1 - 0.0064 17.0 1.0 0.016 15.7 0.0 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20346.1 - 0.032 14.9 0.0 0.11 13.1 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20346.1 - 0.045 14.1 1.8 0.075 13.3 0.6 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20346.1 - 0.18 11.6 1.5 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NAP PF00956.13 GAM20347.1 - 1.3e-08 34.2 7.3 3.1e-08 33.0 5.1 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) AOX PF01786.12 GAM20348.1 - 5.2e-79 264.4 0.9 6.9e-79 264.0 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.8 GAM20348.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 AKAP7_NLS PF10469.4 GAM20349.1 - 7.4e-29 100.9 0.0 8.9e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 GAM20349.1 - 8e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 GAM20349.1 - 0.0037 17.2 0.0 1.4 8.9 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase DRAT PF07357.6 GAM20349.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) MOSC_N PF03476.11 GAM20350.1 - 1.1e-31 109.0 0.0 3.3e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAM20350.1 - 4.1e-20 71.5 0.0 7.1e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain FYVE PF01363.16 GAM20354.1 - 8e-21 73.7 11.6 1.4e-20 72.9 8.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAM20354.1 - 4.2e-12 46.1 3.3 1.6e-11 44.2 0.6 2.4 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.11 GAM20354.1 - 0.0047 16.8 6.3 0.0082 16.0 4.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger PH_11 PF15413.1 GAM20354.1 - 0.1 12.8 2.5 0.15 12.3 0.5 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain zf-DHHC PF01529.15 GAM20354.1 - 2.1 7.7 7.5 1.4 8.3 3.3 2.1 2 1 0 2 2 2 0 DHHC palmitoyltransferase RhoGEF PF00621.15 GAM20355.1 - 1.5e-51 174.8 2.1 2.3e-51 174.2 1.5 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF965 PF06135.7 GAM20355.1 - 6.3 6.9 6.1 1.2 9.2 0.1 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF965) ATG16 PF08614.6 GAM20356.1 - 0.0088 15.8 15.3 0.01 15.6 4.4 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) PhoU PF01895.14 GAM20356.1 - 0.0095 16.3 1.2 0.022 15.2 0.8 1.6 1 0 0 1 1 1 1 PhoU domain FlaC_arch PF05377.6 GAM20356.1 - 0.012 15.4 1.8 0.046 13.6 1.2 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CSTF_C PF14304.1 GAM20356.1 - 0.023 13.9 0.7 0.046 12.9 0.5 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Mnd1 PF03962.10 GAM20356.1 - 0.037 13.6 3.2 0.06 12.9 2.2 1.3 1 0 0 1 1 1 0 Mnd1 family DUF724 PF05266.9 GAM20356.1 - 0.24 11.0 5.7 0.44 10.1 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Histone_HNS PF00816.16 GAM20356.1 - 0.59 10.6 2.8 0.88 10.1 0.9 1.9 1 1 1 2 2 2 0 H-NS histone family IncA PF04156.9 GAM20356.1 - 0.72 9.4 6.6 1.1 8.8 4.6 1.2 1 0 0 1 1 1 0 IncA protein DUF641 PF04859.7 GAM20356.1 - 0.76 9.5 4.8 0.72 9.6 2.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_2 PF07716.10 GAM20356.1 - 1.2 9.0 13.9 0.23 11.2 0.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper TMCO5 PF14992.1 GAM20356.1 - 4.9 6.1 11.1 0.098 11.7 2.3 1.9 2 0 0 2 2 2 0 TMCO5 family TMF_DNA_bd PF12329.3 GAM20356.1 - 7.8 6.3 17.3 0.16 11.7 6.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Abhydro_lipase PF04083.11 GAM20357.1 - 6.9e-17 60.5 0.1 6.9e-17 60.5 0.1 2.2 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 GAM20357.1 - 3.5e-08 33.6 0.0 8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM20357.1 - 1.3e-07 31.5 0.0 7e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Macoilin PF09726.4 GAM20357.1 - 0.043 12.1 17.5 0.063 11.5 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF647 PF04884.9 GAM20358.1 - 1.7e-81 273.1 1.8 2.2e-81 272.7 1.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis BURP PF03181.10 GAM20358.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 BURP domain DUF3128 PF11326.3 GAM20359.1 - 3.6e-13 49.4 1.6 6e-13 48.7 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3128) Peptidase_S15 PF02129.13 GAM20359.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) UDG PF03167.14 GAM20359.1 - 0.082 12.3 0.1 0.84 9.0 0.0 2.2 2 1 0 2 2 2 0 Uracil DNA glycosylase superfamily FNIP PF05725.7 GAM20360.1 - 1.5e-71 236.0 35.3 4.6e-12 45.6 3.2 10.9 6 2 5 12 12 12 11 FNIP Repeat RNA_pol_L_2 PF13656.1 GAM20361.1 - 5.9e-29 99.3 0.2 1e-28 98.5 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAM20361.1 - 1.3e-11 43.4 0.0 2e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TGT PF01702.13 GAM20362.1 - 2.2e-92 308.6 0.0 2.8e-92 308.2 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DEAD PF00270.24 GAM20363.1 - 3.1e-41 140.6 0.2 4.4e-41 140.1 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM20363.1 - 2.5e-24 84.9 0.2 4.7e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM20363.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit FNIP PF05725.7 GAM20364.1 - 5.7e-63 208.6 24.7 4.8e-11 42.4 0.2 9.5 3 1 5 10 10 10 10 FNIP Repeat FNIP PF05725.7 GAM20365.1 - 3.1e-97 318.3 43.7 2e-12 46.8 0.4 11.3 4 3 11 15 15 15 14 FNIP Repeat F-box PF00646.28 GAM20365.1 - 0.003 17.1 0.1 0.0074 15.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM20365.1 - 0.01 15.5 1.1 0.13 12.0 0.1 2.7 2 0 0 2 2 2 0 F-box-like SQS_PSY PF00494.14 GAM20366.1 - 2.5e-41 141.7 0.3 3.1e-41 141.4 0.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase RHH_1 PF01402.16 GAM20366.1 - 0.017 14.9 0.1 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family RNA_pol_A_bac PF01000.21 GAM20367.1 - 2.5e-34 117.7 0.0 4.6e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAM20367.1 - 3.9e-10 38.7 0.0 4.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ABC_membrane_2 PF06472.10 GAM20368.1 - 6.9e-50 169.7 6.2 1e-49 169.2 4.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAM20368.1 - 1.3e-15 57.9 0.0 2.9e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM20368.1 - 1.1e-05 25.5 0.3 4.1e-05 23.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 GAM20368.1 - 2.8e-05 22.9 0.8 0.00015 20.5 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_16 PF13191.1 GAM20368.1 - 0.0005 20.1 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 GAM20368.1 - 0.01 15.0 0.0 0.027 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM20368.1 - 0.019 14.4 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 GAM20368.1 - 0.024 13.3 0.0 0.051 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 GAM20368.1 - 0.029 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 GAM20368.1 - 0.031 13.7 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAM20368.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM20368.1 - 0.14 11.8 0.1 0.44 10.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Translin PF01997.11 GAM20369.1 - 2.7e-48 164.2 0.4 3.2e-48 164.0 0.3 1.0 1 0 0 1 1 1 1 Translin family Tctex-1 PF03645.8 GAM20369.1 - 0.093 12.5 0.1 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Tctex-1 family Ribosomal_L7Ae PF01248.21 GAM20370.1 - 2.6e-23 81.3 0.0 3e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DPBB_1 PF03330.13 GAM20370.1 - 0.12 12.4 0.0 3.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Hydrolase_6 PF13344.1 GAM20370.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase GST_N PF02798.15 GAM20371.1 - 4.9e-14 52.2 0.0 1e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM20371.1 - 2e-08 34.0 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM20371.1 - 3e-07 30.8 0.0 5.3e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM20371.1 - 5.3e-06 26.5 0.0 9.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM20371.1 - 0.00028 20.7 0.3 0.0011 18.8 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM20371.1 - 0.031 14.2 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WH2 PF02205.15 GAM20372.1 - 5e-11 41.8 1.2 1e-10 40.8 0.8 1.6 1 0 0 1 1 1 1 WH2 motif zf-RING_2 PF13639.1 GAM20373.1 - 9.6e-05 22.1 8.4 9.6e-05 22.1 5.8 8.3 5 3 1 6 6 6 2 Ring finger domain Sgf11 PF08209.6 GAM20373.1 - 0.0005 19.3 0.4 0.0005 19.3 0.3 4.8 6 0 0 6 6 6 1 Sgf11 (transcriptional regulation protein) Sporozoite_P67 PF05642.6 GAM20373.1 - 0.76 7.5 9.3 1.6 6.5 6.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAM20373.1 - 1 9.1 33.3 2.4 7.9 23.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Patched PF02460.13 GAM20374.1 - 3e-96 323.1 5.8 2e-94 317.1 2.8 2.3 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.3 GAM20374.1 - 1.1e-48 164.5 8.3 1.1e-48 164.5 5.7 3.8 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 GAM20374.1 - 0.67 7.2 19.5 1.1 6.6 13.5 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family RRM_1 PF00076.17 GAM20375.1 - 1.2e-44 149.8 0.0 1e-19 69.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20375.1 - 9.9e-30 102.3 0.0 6.9e-11 41.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20375.1 - 4.2e-21 74.5 0.1 2.9e-07 30.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM20375.1 - 0.00013 21.6 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 GAM20375.1 - 0.00033 20.3 0.0 1 9.1 0.0 2.9 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 GAM20375.1 - 0.025 14.4 0.0 23 4.9 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif CENP-B_dimeris PF09026.5 GAM20376.1 - 0.0077 16.4 5.7 0.0077 16.4 4.0 2.8 3 0 0 3 3 3 1 Centromere protein B dimerisation domain TMF_DNA_bd PF12329.3 GAM20376.1 - 0.013 15.3 0.6 0.013 15.3 0.4 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CCDC92 PF14916.1 GAM20376.1 - 0.044 13.3 2.3 0.12 11.9 1.1 2.2 1 1 0 1 1 1 0 Coiled-coil domain of unknown function IncA PF04156.9 GAM20376.1 - 6.2 6.3 6.2 9.8 5.7 4.3 1.3 1 0 0 1 1 1 0 IncA protein Spt5_N PF11942.3 GAM20376.1 - 10 6.8 29.4 0.31 11.6 10.5 3.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.27 GAM20377.1 - 6.5e-18 63.8 16.1 1.1e-08 34.6 0.5 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 GAM20377.1 - 2.8e-13 48.9 0.6 2.8e-13 48.9 0.4 2.2 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 PQQ_2 PF13360.1 GAM20377.1 - 0.015 14.8 0.2 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain TBPIP PF07106.8 GAM20377.1 - 0.044 13.3 4.7 2.8 7.4 1.1 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HEAT PF02985.17 GAM20378.1 - 2.4e-14 52.0 18.8 0.034 14.2 0.1 11.0 13 0 0 13 13 10 4 HEAT repeat HEAT_EZ PF13513.1 GAM20378.1 - 6.4e-14 51.9 0.1 0.05 14.0 0.0 8.6 7 2 3 10 10 9 1 HEAT-like repeat HEAT_2 PF13646.1 GAM20378.1 - 4.7e-13 49.2 0.1 0.0036 17.5 0.0 8.2 5 3 6 11 11 10 2 HEAT repeats Cnd1 PF12717.2 GAM20378.1 - 5.9e-10 39.2 9.9 0.0018 18.1 0.2 4.9 3 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 GAM20378.1 - 5.3e-09 36.3 2.2 0.0037 17.6 0.1 6.1 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 GAM20378.1 - 4.1e-06 25.3 8.6 9.4e-05 20.9 0.3 4.5 2 2 2 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.3 GAM20378.1 - 1.6e-05 24.4 4.5 0.36 10.1 0.0 5.2 4 1 1 6 6 6 2 CLASP N terminal IBN_N PF03810.14 GAM20378.1 - 5.4e-05 23.0 4.0 0.0008 19.2 1.2 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1981 PF09324.5 GAM20378.1 - 0.00046 19.6 0.4 0.72 9.4 0.0 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) CENP-B_dimeris PF09026.5 GAM20378.1 - 0.001 19.2 3.8 0.001 19.2 2.6 2.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Ipi1_N PF12333.3 GAM20378.1 - 0.0023 17.8 0.1 1.6 8.7 0.0 4.5 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation DUF4042 PF13251.1 GAM20378.1 - 0.0084 15.5 0.2 0.94 8.9 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) Arm PF00514.18 GAM20378.1 - 0.069 13.0 4.9 37 4.3 0.0 5.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Sigma70_ner PF04546.8 GAM20378.1 - 0.58 9.7 10.3 1.7 8.1 1.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region RXT2_N PF08595.6 GAM20378.1 - 2.6 7.8 9.4 14 5.4 2.3 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Ras PF00071.17 GAM20379.1 - 8.5e-53 178.0 0.0 1e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM20379.1 - 2.3e-17 63.6 0.1 3.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM20379.1 - 1.7e-08 33.9 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM20379.1 - 0.00056 19.8 0.0 0.00071 19.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ser_hydrolase PF06821.8 GAM20379.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Serglycin PF04360.7 GAM20380.1 - 0.0011 18.7 4.0 0.0021 17.7 2.8 1.5 1 0 0 1 1 1 1 Serglycin DUF2457 PF10446.4 GAM20380.1 - 0.12 11.1 22.2 0.18 10.5 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) POX PF07526.6 GAM20380.1 - 0.42 10.8 2.1 0.61 10.3 0.8 1.8 1 1 0 1 1 1 0 Associated with HOX Lin-8 PF03353.10 GAM20380.1 - 1.1 8.4 10.3 1.6 7.9 7.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NicO PF03824.11 GAM20380.1 - 2.5 7.3 5.2 3.7 6.7 3.6 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pyridox_oxidase PF01243.15 GAM20381.1 - 3.2e-13 49.4 0.0 6.7e-07 29.2 0.0 2.8 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 GAM20381.1 - 7.3e-08 32.9 0.0 2.1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM20381.1 - 9e-08 32.1 0.1 6.3e-06 26.2 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAM20381.1 - 1.5e-07 31.4 0.0 4.2e-07 29.9 0.0 1.7 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DEAD PF00270.24 GAM20382.1 - 1.7e-36 125.2 0.0 2.8e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM20382.1 - 5.4e-26 90.2 0.1 5.5e-25 87.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM20382.1 - 0.00039 20.3 0.1 0.0013 18.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAM20382.1 - 0.0024 17.0 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DnaB_C PF03796.10 GAM20382.1 - 0.03 13.2 0.2 1.9 7.3 0.1 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RCC1 PF00415.13 GAM20383.1 - 6.7e-75 247.1 16.5 7.3e-15 54.9 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.14 GAM20383.1 - 1.4e-45 155.3 0.0 1.4e-45 155.3 0.0 3.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RCC1_2 PF13540.1 GAM20383.1 - 4e-39 131.4 23.9 2.8e-07 29.9 0.1 8.3 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.15 GAM20383.1 - 7.9e-24 84.5 3.1 7.9e-24 84.5 2.2 2.4 2 1 0 2 2 2 1 RhoGEF domain CAF-1_p150 PF11600.3 GAM20383.1 - 1.6e-05 24.3 33.7 1.6e-05 24.3 23.4 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CCDC66 PF15236.1 GAM20383.1 - 0.087 12.4 25.2 0.22 11.1 17.5 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Response_reg PF00072.19 GAM20385.1 - 1.9e-30 105.1 0.2 4e-23 81.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 GAM20385.1 - 1.4e-17 63.4 0.0 3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Y_phosphatase PF00102.22 GAM20386.1 - 2.9e-73 246.0 0.4 2.9e-73 246.0 0.2 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM20386.1 - 0.00012 21.6 0.0 0.0004 19.9 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAM20386.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.5 3 0 0 3 3 3 0 Tyrosine phosphatase family RA PF00788.18 GAM20387.1 - 8.2e-05 23.0 0.1 0.041 14.3 0.0 3.5 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Mito_fiss_reg PF05308.6 GAM20387.1 - 0.019 14.3 0.1 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator FERM_N PF09379.5 GAM20387.1 - 0.035 14.1 0.0 0.48 10.5 0.0 2.8 3 0 0 3 3 3 0 FERM N-terminal domain TAF4 PF05236.9 GAM20388.1 - 1.4e-32 112.9 10.2 1.4e-32 112.9 7.1 5.1 6 1 0 6 6 6 1 Transcription initiation factor TFIID component TAF4 family CAF-1_p150 PF11600.3 GAM20388.1 - 3e-06 26.7 35.7 3e-06 26.7 24.7 6.8 5 2 2 7 7 7 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 GAM20388.1 - 0.0059 16.2 14.4 0.0059 16.2 10.0 8.2 2 2 4 7 7 7 1 Transcriptional regulator of RNA polII, SAGA, subunit Pkinase PF00069.20 GAM20389.1 - 1.2e-76 257.2 0.0 2e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20389.1 - 5.5e-34 117.4 0.0 9.9e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM20389.1 - 5.5e-10 38.6 0.0 1.8e-08 33.7 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FHA PF00498.21 GAM20389.1 - 5.7e-07 29.5 0.3 7.3e-06 26.0 0.2 2.7 1 1 0 1 1 1 1 FHA domain Kdo PF06293.9 GAM20389.1 - 0.0045 16.0 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20389.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM20389.1 - 0.077 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF504 PF04457.7 GAM20390.1 - 0.00018 21.6 2.5 0.00075 19.6 1.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF504) MucB_RseB PF03888.9 GAM20391.1 - 0.0024 16.9 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 MucB/RseB family Kelch_1 PF01344.20 GAM20393.1 - 5.7e-30 102.6 5.0 1.1e-10 40.8 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM20393.1 - 7.7e-29 98.6 7.6 9.1e-07 28.7 0.0 6.6 4 1 2 6 6 6 5 Kelch motif Kelch_4 PF13418.1 GAM20393.1 - 8.9e-27 92.6 0.8 2.8e-06 26.9 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM20393.1 - 4.6e-22 77.5 2.1 3e-06 27.2 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM20393.1 - 5.9e-18 63.8 1.9 0.0017 18.0 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 GAM20393.1 - 4.7e-10 39.1 7.2 0.015 15.2 0.1 5.2 5 0 0 5 5 5 3 Kelch motif TMCO5 PF14992.1 GAM20393.1 - 0.0029 16.7 1.1 0.0045 16.1 0.8 1.2 1 0 0 1 1 1 1 TMCO5 family Ank_2 PF12796.2 GAM20394.1 - 8.3e-25 86.9 0.2 9.1e-12 45.1 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM20394.1 - 6e-24 82.6 0.1 1e-05 25.0 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAM20394.1 - 7.5e-21 73.6 0.1 3.1e-09 36.7 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20394.1 - 5.4e-20 71.3 0.1 3.6e-08 33.7 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20394.1 - 1.9e-19 67.8 0.0 0.00043 20.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Inhibitor_I53 PF11714.3 GAM20394.1 - 0.11 12.4 2.4 0.25 11.3 1.7 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin WD40 PF00400.27 GAM20395.1 - 6.4e-45 149.4 15.5 3.7e-10 39.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 GAM20395.1 - 1.1e-34 117.9 1.2 2.7e-34 116.6 0.9 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like eIF2A PF08662.6 GAM20395.1 - 2.6e-11 43.5 1.6 0.00045 19.9 0.0 3.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM20395.1 - 0.0002 19.6 2.5 0.46 8.5 0.0 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 GAM20395.1 - 0.0013 16.6 0.7 0.0099 13.7 0.0 2.1 2 0 0 2 2 2 1 IKI3 family Nbas_N PF15492.1 GAM20395.1 - 0.0023 17.0 0.2 0.025 13.7 0.0 2.6 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal zf-Nse PF11789.3 GAM20395.1 - 0.0024 17.3 0.0 0.087 12.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Peptidase_S7 PF00949.16 GAM20395.1 - 0.0082 15.5 0.1 0.095 12.0 0.0 2.4 1 1 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Apc4_WD40 PF12894.2 GAM20395.1 - 0.09 12.3 0.0 7.8 6.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3886 PF13025.1 GAM20395.1 - 0.24 11.3 2.9 0.56 10.1 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) MFS_1 PF07690.11 GAM20396.1 - 1e-25 90.2 47.7 3.3e-25 88.5 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-5_eIF-2B PF01873.12 GAM20398.1 - 5.3e-33 113.3 0.9 1.7e-32 111.6 0.2 2.0 2 1 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 GAM20398.1 - 6.6e-21 74.0 2.6 6.6e-21 74.0 1.8 4.2 2 1 1 3 3 2 1 eIF4-gamma/eIF5/eIF2-epsilon CobT PF06213.7 GAM20398.1 - 0.0033 16.6 7.4 0.0033 16.6 5.1 2.3 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT Lenti_VIF_2 PF07401.7 GAM20398.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Bovine Lentivirus VIF protein TLP-20 PF06088.6 GAM20398.1 - 0.052 13.2 10.9 0.066 12.8 2.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.6 GAM20398.1 - 0.11 11.9 25.8 0.36 10.3 1.3 2.3 2 0 0 2 2 2 0 PPP4R2 Zip PF02535.17 GAM20398.1 - 0.27 10.2 2.3 4.6 6.1 0.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Prothymosin PF03247.9 GAM20398.1 - 0.64 10.1 42.0 1 9.5 2.4 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family SMN PF06003.7 GAM20398.1 - 2.9 6.9 10.3 2.8 6.9 0.5 2.3 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Daxx PF03344.10 GAM20398.1 - 5.6 5.3 32.0 0.55 8.6 1.2 2.1 2 0 0 2 2 2 0 Daxx Family BUD22 PF09073.5 GAM20398.1 - 9 5.2 30.5 0.29 10.1 2.1 2.2 2 0 0 2 2 2 0 BUD22 2OG-FeII_Oxy_2 PF13532.1 GAM20399.1 - 2.1e-21 76.6 0.0 3.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM20399.1 - 7.4e-07 29.3 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily His_binding PF02098.11 GAM20399.1 - 0.096 12.5 1.6 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Tick histamine binding protein DM13 PF10517.4 GAM20399.1 - 0.16 12.3 1.1 0.27 11.6 0.8 1.3 1 0 0 1 1 1 0 Electron transfer DM13 Pcc1 PF09341.5 GAM20400.1 - 2.1e-09 37.2 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Peptidase_S10 PF00450.17 GAM20400.1 - 0.065 12.3 0.4 0.072 12.2 0.3 1.0 1 0 0 1 1 1 0 Serine carboxypeptidase FNIP PF05725.7 GAM20403.1 - 6e-81 266.1 45.7 1.3e-13 50.6 0.0 10.3 5 2 2 10 10 10 10 FNIP Repeat Sulfotransfer_1 PF00685.22 GAM20403.1 - 0.13 11.5 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain Lipoprotein_17 PF04200.7 GAM20403.1 - 6.2 7.0 7.7 22 5.2 0.3 3.9 4 0 0 4 4 4 0 Lipoprotein associated domain ATP-synt_ab PF00006.20 GAM20404.1 - 1.5e-112 374.3 0.0 3.2e-112 373.2 0.0 1.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM20404.1 - 1e-22 80.7 0.1 1.7e-22 80.0 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM20404.1 - 1.7e-15 57.0 2.5 7.3e-15 54.9 0.9 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 GAM20404.1 - 0.031 14.1 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SID-1_RNA_chan PF13965.1 GAM20407.1 - 7.4e-77 258.8 31.3 9.1e-77 258.5 21.7 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Secretin_N_2 PF07655.8 GAM20408.1 - 2.5 8.5 18.9 7.6 7.0 11.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Catalase PF00199.14 GAM20409.1 - 7.8e-180 597.5 0.7 9.2e-180 597.3 0.5 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 GAM20409.1 - 2e-20 72.4 0.0 4.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive EF-hand_1 PF00036.27 GAM20410.1 - 6.4e-21 72.0 4.7 1.1e-06 27.5 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 GAM20410.1 - 1.8e-20 72.8 5.4 1.2e-11 44.5 0.3 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM20410.1 - 1.6e-18 65.1 6.8 9.7e-08 31.0 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAM20410.1 - 3.2e-17 60.7 6.2 0.00018 21.0 0.0 5.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAM20410.1 - 2.8e-11 42.8 6.1 0.0024 17.4 0.1 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 GAM20410.1 - 8.7e-06 25.4 0.3 0.01 15.5 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAM20410.1 - 2.6e-05 24.2 0.2 1.3 9.0 0.0 3.4 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3890 PF13029.1 GAM20410.1 - 0.062 13.3 3.1 1.2 9.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3890) EF-hand_10 PF14788.1 GAM20410.1 - 0.11 12.1 2.7 0.32 10.7 0.3 2.7 3 0 0 3 3 3 0 EF hand Pkinase PF00069.20 GAM20411.1 - 6.4e-61 205.7 0.0 1.1e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20411.1 - 6.2e-60 202.4 0.0 8.8e-60 201.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM20411.1 - 0.003 17.3 0.0 0.012 15.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family B2 PF11473.3 GAM20411.1 - 0.032 13.8 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding protein B2 Kdo PF06293.9 GAM20411.1 - 0.047 12.7 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MOSC PF03473.12 GAM20412.1 - 2.6e-11 43.1 0.0 3.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 MOSC domain Trehalase PF01204.13 GAM20413.1 - 2.3e-13 49.6 0.1 2.4e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase PF01204.13 GAM20415.1 - 1.4e-143 479.2 1.3 1.6e-143 479.0 0.9 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 GAM20415.1 - 5.6e-05 22.0 0.0 0.00011 21.0 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Ank_2 PF12796.2 GAM20419.1 - 7.7e-05 22.9 0.0 0.033 14.5 0.0 3.6 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Halogen_Hydrol PF10112.4 GAM20419.1 - 0.066 12.6 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Na_H_antiport_1 PF06965.7 GAM20419.1 - 0.088 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Ank_3 PF13606.1 GAM20419.1 - 0.15 12.3 6.8 45 4.7 0.1 6.4 7 0 0 7 7 7 0 Ankyrin repeat zf-UBR PF02207.15 GAM20420.1 - 2.6e-18 65.4 7.8 2.6e-18 65.4 5.4 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) LIM PF00412.17 GAM20421.1 - 8.6e-45 150.6 67.2 1.7e-11 44.0 2.4 5.5 5 0 0 5 5 5 5 LIM domain PTEN_C2 PF10409.4 GAM20421.1 - 1.4e-21 76.5 0.6 3.9e-21 75.1 0.4 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 GAM20421.1 - 6.5e-06 25.7 0.0 2.4e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM20421.1 - 0.0001 21.7 0.0 0.0001 21.7 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM20421.1 - 0.006 16.8 0.0 0.006 16.8 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Cyt-b5 PF00173.23 GAM20421.1 - 0.031 14.0 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain PTPlike_phytase PF14566.1 GAM20421.1 - 0.039 13.9 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L37e PF01907.14 GAM20422.1 - 3.6e-26 90.7 11.5 6.5e-26 89.9 8.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.13 GAM20422.1 - 0.0018 17.9 0.4 0.0026 17.4 0.3 1.3 1 1 0 1 1 1 1 SelR domain DZR PF12773.2 GAM20422.1 - 0.0023 17.7 2.0 0.0033 17.2 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.17 GAM20422.1 - 0.076 12.7 2.1 0.12 12.0 1.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_6 PF14599.1 GAM20422.1 - 0.42 10.4 2.1 0.67 9.7 1.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon GFA PF04828.9 GAM20422.1 - 0.8 9.6 4.7 5.5 7.0 1.4 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 GAM20422.1 - 4.2 7.2 5.5 41 4.1 1.5 2.5 1 1 2 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-CCCH PF00642.19 GAM20423.1 - 2.3e-20 71.8 16.9 1.6e-10 40.4 3.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAM20423.1 - 0.0034 17.3 10.9 0.063 13.2 0.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type UBX PF00789.15 GAM20424.1 - 5.2e-15 55.2 0.4 8.5e-11 41.7 0.0 2.9 3 0 0 3 3 3 2 UBX domain TUG-UBL1 PF11470.3 GAM20424.1 - 3.8e-14 52.3 0.2 3.8e-14 52.3 0.1 2.3 2 0 0 2 2 2 1 GLUT4 regulating protein TUG Med3 PF11593.3 GAM20424.1 - 0.039 13.2 24.2 0.13 11.5 1.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RhoGEF PF00621.15 GAM20425.1 - 1e-39 136.2 5.6 2.8e-39 134.8 3.9 1.8 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.26 GAM20425.1 - 5.1e-25 87.6 1.0 7.8e-12 45.1 0.1 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.22 GAM20425.1 - 0.00014 21.1 1.6 0.00046 19.5 1.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 GAM20425.1 - 0.0069 16.0 0.2 0.13 11.9 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain PH_10 PF15411.1 GAM20425.1 - 0.036 14.2 0.2 0.036 14.2 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH PF00169.24 GAM20425.1 - 0.054 13.7 2.1 0.13 12.5 0.6 2.2 2 1 0 2 2 2 0 PH domain Tetraspannin PF00335.15 GAM20426.1 - 0.0013 18.0 11.8 0.0013 18.0 8.2 2.0 1 1 1 2 2 2 1 Tetraspanin family DUF1218 PF06749.7 GAM20426.1 - 0.049 14.0 3.3 0.15 12.4 2.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) NfeD PF01957.13 GAM20426.1 - 0.46 10.6 10.0 0.47 10.5 0.4 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Claudin_2 PF13903.1 GAM20426.1 - 0.79 9.3 12.8 0.82 9.3 8.2 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Tweety PF04906.8 GAM20426.1 - 1.7 7.0 6.5 0.57 8.5 3.0 1.4 1 1 0 1 1 1 0 Tweety YjgP_YjgQ PF03739.9 GAM20426.1 - 5.1 5.7 13.2 15 4.1 9.1 1.8 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family CoA_binding_3 PF13727.1 GAM20426.1 - 5.4 6.7 8.0 1 9.1 3.1 1.6 1 1 1 2 2 2 0 CoA-binding domain CD20 PF04103.10 GAM20426.1 - 5.9 6.8 15.0 13 5.6 10.4 1.6 1 1 0 1 1 1 0 CD20-like family MpPF26 PF07666.6 GAM20426.1 - 9.3 6.1 12.4 0.56 10.0 3.5 2.2 1 1 1 2 2 2 0 M penetrans paralogue family 26 PRMT5 PF05185.11 GAM20427.1 - 2e-163 544.4 0.4 2.5e-163 544.1 0.3 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 GAM20427.1 - 1.9e-05 24.3 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 GAM20427.1 - 0.00059 20.3 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM20427.1 - 0.0054 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAM20427.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 AMP-binding PF00501.23 GAM20428.1 - 3.8e-90 302.2 0.0 5e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CBM49 PF09478.5 GAM20429.1 - 4e-10 39.6 12.9 0.0025 17.8 0.2 5.4 6 0 0 6 6 6 3 Carbohydrate binding domain CBM49 WD40 PF00400.27 GAM20430.1 - 1.1e-44 148.7 22.4 1.3e-09 37.5 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM20430.1 - 0.033 13.9 0.4 1.4 8.7 0.1 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 GAM20430.1 - 0.36 8.5 7.7 0.22 9.2 0.4 2.4 1 1 2 3 3 3 0 IKI3 family AAA PF00004.24 GAM20431.1 - 3.6e-39 134.0 0.0 6.4e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAM20431.1 - 2.9e-22 78.3 0.0 2e-21 75.6 0.0 2.3 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 GAM20431.1 - 2.4e-19 68.9 4.3 4.9e-19 67.9 3.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 GAM20431.1 - 3.6e-07 30.3 0.2 4.4e-05 23.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM20431.1 - 2.1e-06 27.2 0.4 0.0089 15.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 GAM20431.1 - 6e-06 26.2 0.6 1.6e-05 24.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAM20431.1 - 1.2e-05 24.4 0.0 6.3e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAM20431.1 - 4.4e-05 24.2 0.0 0.00019 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM20431.1 - 6.4e-05 21.8 0.3 0.00027 19.8 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 GAM20431.1 - 0.00013 22.0 0.1 0.00066 19.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAM20431.1 - 0.00015 21.5 0.0 0.00049 19.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAM20431.1 - 0.00019 21.5 0.1 0.00082 19.5 0.0 2.2 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 GAM20431.1 - 0.00023 20.6 0.0 0.00079 18.8 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAM20431.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM20431.1 - 0.00085 18.3 0.0 0.0019 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 GAM20431.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM20431.1 - 0.0072 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM20431.1 - 0.0087 15.1 0.0 0.058 12.4 0.0 2.2 1 1 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 GAM20431.1 - 0.0098 15.0 0.2 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 GAM20431.1 - 0.016 14.3 0.2 3 6.9 0.0 2.5 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.1 GAM20431.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 GAM20431.1 - 0.036 13.7 2.3 0.11 12.1 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 GAM20431.1 - 0.05 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 USP8_dimer PF08969.6 GAM20431.1 - 0.052 13.5 6.6 0.12 12.3 4.6 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_28 PF13521.1 GAM20431.1 - 0.065 13.1 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 GAM20431.1 - 0.07 12.3 0.3 0.22 10.6 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 GAM20431.1 - 0.071 12.5 0.3 1.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 GAM20431.1 - 0.082 11.8 0.2 0.81 8.6 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.11 GAM20431.1 - 0.088 12.0 0.5 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 GAM20431.1 - 0.12 12.0 0.0 0.67 9.5 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 GAM20431.1 - 0.12 11.8 2.9 0.14 11.7 0.1 2.5 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAM20431.1 - 0.14 12.4 0.2 0.95 9.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Pkinase PF00069.20 GAM20432.1 - 3.3e-35 121.4 0.3 3.3e-35 121.4 0.2 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20432.1 - 4.5e-24 84.9 0.1 8.7e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM20432.1 - 1.4e-12 47.5 3.6 2.8e-12 46.6 2.5 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Ank_4 PF13637.1 GAM20432.1 - 1.3e-05 25.6 0.1 0.0073 16.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM20432.1 - 0.00013 22.1 0.0 0.0017 18.6 0.0 2.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20432.1 - 0.00048 20.1 0.0 1 9.8 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat RIO1 PF01163.17 GAM20432.1 - 0.0032 16.8 1.0 0.0065 15.8 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 GAM20432.1 - 0.024 13.6 0.1 0.05 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.1 GAM20432.1 - 0.034 14.4 0.0 12 6.3 0.0 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) APH PF01636.18 GAM20432.1 - 0.064 12.9 0.3 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 GAM20433.1 - 3.7e-22 78.4 0.0 2.1e-07 31.1 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20433.1 - 2.9e-16 59.1 0.2 0.012 15.8 0.0 7.5 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20433.1 - 7.1e-16 58.2 0.9 0.00057 20.3 0.0 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20433.1 - 8.3e-15 53.4 0.1 0.18 12.1 0.0 8.5 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.25 GAM20433.1 - 6.1e-12 44.7 0.2 0.95 9.4 0.0 8.2 8 1 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.2 GAM20434.1 - 1.8e-24 85.9 0.0 5.6e-07 29.8 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20434.1 - 1.9e-19 69.6 0.5 0.00049 20.5 0.0 5.9 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20434.1 - 5.6e-18 63.2 0.6 0.66 10.3 0.0 9.7 9 1 1 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 GAM20434.1 - 2.2e-15 56.2 0.1 0.23 11.7 0.0 8.6 5 3 4 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM20434.1 - 2.6e-12 45.9 0.6 1.3 8.9 0.0 8.5 8 1 1 9 9 9 3 Ankyrin repeat DUF3791 PF12668.2 GAM20434.1 - 0.047 13.2 1.0 0.22 11.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Ank_2 PF12796.2 GAM20435.1 - 2e-27 95.3 0.1 7.2e-09 35.8 0.0 4.6 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20435.1 - 5.7e-20 69.4 2.0 0.0035 17.4 0.0 9.7 8 1 1 9 9 9 4 Ankyrin repeat Ank_4 PF13637.1 GAM20435.1 - 2.8e-19 69.0 4.2 1.8e-05 25.1 0.1 7.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20435.1 - 4.4e-17 61.7 1.2 0.059 13.6 0.0 9.5 4 2 6 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM20435.1 - 8.3e-15 53.7 1.3 0.025 14.3 0.0 8.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_2 PF12796.2 GAM20436.1 - 3e-33 113.9 6.5 1.4e-10 41.3 0.3 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20436.1 - 1.3e-18 66.5 5.8 0.0021 18.2 0.0 7.2 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20436.1 - 8.9e-16 56.4 5.2 0.093 13.0 0.0 7.7 6 2 2 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 GAM20436.1 - 2.3e-15 56.6 6.6 6.3e-06 26.5 0.5 6.1 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM20436.1 - 5.2e-13 48.1 8.6 0.14 12.0 0.0 7.5 7 1 1 8 8 8 4 Ankyrin repeat FANCI_S3 PF14677.1 GAM20436.1 - 0.041 13.2 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 3 Ank_4 PF13637.1 GAM20437.1 - 0.0012 19.3 0.0 0.023 15.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF3666 PF12408.3 GAM20437.1 - 0.0017 17.4 0.5 0.053 12.6 0.0 2.6 2 0 0 2 2 2 1 Ribose-5-phosphate isomerase Ank_2 PF12796.2 GAM20437.1 - 0.024 14.9 0.0 0.58 10.5 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20437.1 - 0.032 14.4 0.0 67 3.9 0.0 4.1 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20437.1 - 0.12 12.6 0.0 28 5.3 0.0 4.0 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.2 GAM20438.1 - 1.2e-26 92.8 0.0 1.7e-07 31.5 0.1 5.7 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20438.1 - 1.1e-15 57.6 6.7 0.00071 20.0 0.0 8.6 6 3 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20438.1 - 2.8e-15 55.9 4.9 0.067 13.4 0.0 10.8 8 4 4 12 12 12 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20438.1 - 2.7e-14 51.8 9.4 1.4 9.3 0.0 11.0 9 3 3 12 12 12 4 Ankyrin repeat Ank PF00023.25 GAM20438.1 - 1.8e-13 49.5 2.8 1.3 8.9 0.0 8.8 7 1 1 8 8 8 5 Ankyrin repeat 14-3-3 PF00244.15 GAM20439.1 - 1.1e-90 302.8 5.7 1.3e-90 302.6 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Ank_2 PF12796.2 GAM20440.1 - 6.6e-09 35.9 1.8 3.2e-06 27.3 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20440.1 - 1.1e-07 31.7 5.6 0.16 12.2 0.0 5.8 2 2 4 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20440.1 - 1.7e-07 31.5 3.1 0.0002 21.8 0.0 5.2 3 3 2 5 5 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM20440.1 - 0.0032 17.1 3.0 19 5.2 0.0 5.9 8 0 0 8 8 8 1 Ankyrin repeat Ank_2 PF12796.2 GAM20441.1 - 1.9e-18 66.6 2.8 3.5e-08 33.6 0.5 5.3 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20441.1 - 8.7e-10 38.5 6.0 0.028 14.6 0.0 8.8 7 2 3 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20441.1 - 1.2e-09 37.4 5.6 13 6.4 0.0 9.4 8 1 2 10 10 10 2 Ankyrin repeat Ank_4 PF13637.1 GAM20441.1 - 5.7e-07 29.8 7.5 0.12 12.9 0.1 7.2 4 4 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM20441.1 - 5.2e-06 25.9 4.6 2.9 7.8 0.0 6.4 5 1 1 6 6 6 2 Ankyrin repeat DUF837 PF05769.6 GAM20442.1 - 1.8e-05 24.3 22.6 1.8e-05 24.3 15.6 3.0 1 1 1 3 3 3 1 Protein of unknown function (DUF837) Preseq_ALAS PF09029.5 GAM20442.1 - 0.1 12.5 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence AIF-MLS PF14962.1 GAM20442.1 - 0.14 11.7 6.1 0.087 12.4 1.7 2.2 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Laminin_II PF06009.7 GAM20442.1 - 0.96 9.2 21.0 0.08 12.7 5.0 3.0 2 2 1 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.4 GAM20442.1 - 6.8 6.9 29.4 0.14 12.2 3.4 4.1 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ank_2 PF12796.2 GAM20443.1 - 1.4e-27 95.7 1.6 2.3e-08 34.2 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20443.1 - 1.2e-23 82.5 7.0 2.3e-06 27.6 0.1 6.5 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM20443.1 - 1.8e-23 81.1 0.4 3.4e-06 26.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAM20443.1 - 3.5e-21 75.1 5.7 3.5e-05 24.1 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20443.1 - 1.3e-18 65.2 0.5 0.00029 20.7 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat G-patch PF01585.18 GAM20444.1 - 1.3e-09 37.7 1.8 2.7e-09 36.6 1.3 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM20444.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 DExH-box splicing factor binding site Arm PF00514.18 GAM20445.1 - 3.8e-83 270.7 8.7 9.7e-13 47.4 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM20445.1 - 3.2e-25 88.2 0.0 2e-08 34.3 0.0 5.7 3 2 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 GAM20445.1 - 5e-23 80.9 0.5 6.4e-09 36.0 0.0 6.1 5 2 2 7 7 6 5 HEAT-like repeat HEAT PF02985.17 GAM20445.1 - 3.2e-17 61.0 0.3 4.6e-06 26.2 0.0 7.7 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.15 GAM20445.1 - 3.7e-12 46.2 9.9 1.2e-11 44.6 6.8 1.7 1 1 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 GAM20445.1 - 8.6e-08 31.5 0.0 0.021 13.9 0.0 3.2 3 0 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.3 GAM20445.1 - 5.3e-06 26.3 0.0 0.37 10.7 0.0 4.3 3 1 1 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.15 GAM20445.1 - 0.0002 19.8 0.0 0.0027 16.1 0.0 2.6 1 1 0 1 1 1 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 GAM20445.1 - 0.0002 19.7 1.4 0.16 10.2 0.2 2.8 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 GAM20445.1 - 0.0011 19.2 1.3 1.4 9.5 0.0 5.0 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 GAM20445.1 - 0.0016 18.3 1.5 4.8 7.1 0.0 4.4 2 2 4 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 RRM_1 PF00076.17 GAM20446.1 - 2.4e-19 68.7 0.0 4.2e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20446.1 - 9.7e-13 47.9 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20446.1 - 1.4e-12 47.2 0.1 2.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM20446.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif IBR PF01485.16 GAM20447.1 - 5.4e-19 67.8 23.6 5.5e-11 42.1 5.7 4.6 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 GAM20447.1 - 0.00083 19.3 11.7 0.00083 19.3 8.1 5.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM20447.1 - 0.0041 16.9 10.3 0.0041 16.9 7.1 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM20447.1 - 0.92 9.2 43.0 0.11 12.2 6.8 4.3 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.7 GAM20449.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 FNIP Repeat RNA_pol_Rpb1_5 PF04998.12 GAM20449.1 - 0.098 11.8 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Phage_holin PF04688.8 GAM20450.1 - 0.13 11.7 7.1 0.18 11.3 4.9 1.4 1 1 0 1 1 1 0 Phage lysis protein, holin Mucin PF01456.12 GAM20450.1 - 2.7 7.7 19.0 2.8 7.7 13.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein AflR PF08493.5 GAM20450.1 - 3.4 6.6 9.3 3.7 6.5 6.5 1.0 1 0 0 1 1 1 0 Aflatoxin regulatory protein Myco_19_kDa PF05481.7 GAM20450.1 - 4.4 7.1 10.1 5.2 6.8 7.0 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Pex14_N PF04695.8 GAM20450.1 - 7 6.7 7.4 6.8 6.7 5.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAG1 PF12940.2 GAM20451.1 - 0.079 11.2 1.1 1.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Recombination-activation protein 1 (RAG1) zf-RVT PF13966.1 GAM20451.1 - 0.12 12.6 2.2 2.1 8.7 0.7 2.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Nup35_RRM_2 PF14605.1 GAM20452.1 - 0.056 13.2 0.2 6.4 6.6 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Pox_F17 PF04767.7 GAM20452.1 - 6 7.1 9.4 0.69 10.2 2.8 1.9 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein GAT PF03127.9 GAM20454.1 - 0.067 13.1 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 GAT domain DUF1374 PF07118.6 GAM20455.1 - 0.13 12.3 0.4 2.3 8.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) Nup35_RRM_2 PF14605.1 GAM20457.1 - 0.056 13.2 0.2 6.4 6.6 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Pox_F17 PF04767.7 GAM20457.1 - 6 7.1 9.4 0.69 10.2 2.8 1.9 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein Kinesin PF00225.18 GAM20458.1 - 1.1e-98 330.0 3.1 1.1e-98 330.0 2.1 2.1 3 0 0 3 3 3 1 Kinesin motor domain ADIP PF11559.3 GAM20458.1 - 0.72 9.7 42.1 0.22 11.4 11.1 3.2 2 2 0 2 2 2 0 Afadin- and alpha -actinin-Binding FNIP PF05725.7 GAM20459.1 - 3.5e-99 324.5 36.6 5e-16 58.3 0.9 11.6 6 3 2 11 11 11 11 FNIP Repeat Neurochondrin PF05536.6 GAM20460.1 - 2.6e-36 125.0 9.5 5.4e-19 67.9 1.3 2.3 2 0 0 2 2 2 2 Neurochondrin ESSS PF10183.4 GAM20461.1 - 0.034 14.5 0.0 0.067 13.5 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Paramyxo_C PF01692.13 GAM20461.1 - 0.061 12.9 1.6 0.1 12.1 1.1 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Acetyltransf_7 PF13508.1 GAM20462.1 - 7.2e-08 32.4 0.0 9.4e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM20462.1 - 8e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM20462.1 - 0.00028 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAM20462.1 - 0.00096 19.2 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FNIP PF05725.7 GAM20463.1 - 1.6e-55 184.7 19.8 1.6e-11 43.9 0.1 6.4 4 1 1 6 6 6 6 FNIP Repeat Pyridox_oxidase PF01243.15 GAM20464.1 - 5.6e-21 74.3 0.0 8.6e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 GAM20464.1 - 7.8e-15 54.1 2.6 2.1e-14 52.7 1.8 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Rad51 PF08423.6 GAM20465.1 - 1.4e-30 106.0 0.1 8.9e-30 103.4 0.1 2.2 2 1 0 2 2 2 1 Rad51 AAA_25 PF13481.1 GAM20465.1 - 8e-16 58.0 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM20465.1 - 1e-08 34.5 0.6 3.8e-08 32.7 0.4 1.9 1 1 0 1 1 1 1 KaiC RecA PF00154.16 GAM20465.1 - 0.00013 21.1 0.1 0.0031 16.6 0.0 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 GAM20465.1 - 0.0004 20.5 0.8 0.003 17.7 0.6 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 GAM20465.1 - 0.00073 19.0 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.24 GAM20465.1 - 0.0023 18.1 0.0 0.0074 16.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 GAM20465.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.11 GAM20465.1 - 0.022 13.9 0.0 0.061 12.5 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 GAM20465.1 - 0.14 12.5 3.9 1.1 9.5 2.7 2.3 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 GAM20465.1 - 0.14 12.9 0.0 0.49 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 GAM20467.1 - 8e-37 126.3 8.1 1.5e-36 125.4 5.6 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase MatE PF01554.13 GAM20467.1 - 0.0064 16.1 1.5 0.0092 15.6 1.1 1.2 1 0 0 1 1 1 1 MatE Col_cuticle_N PF01484.12 GAM20467.1 - 0.14 11.8 3.5 0.24 11.1 2.4 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain GTP_cyclohydroI PF01227.17 GAM20469.1 - 3.6e-75 251.1 0.2 4.6e-75 250.8 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 GAM20469.1 - 0.00051 19.9 0.1 0.0063 16.4 0.0 2.2 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 GAM20469.1 - 0.024 14.4 0.2 0.057 13.1 0.2 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Condensin2nSMC PF12422.3 GAM20470.1 - 3.9e-44 150.0 0.4 1.9e-43 147.8 0.0 2.5 2 0 0 2 2 2 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 GAM20470.1 - 0.00041 20.1 0.2 6.8 7.0 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat CLASP_N PF12348.3 GAM20470.1 - 0.0014 18.0 5.9 0.1 11.9 0.1 3.7 3 1 1 4 4 4 2 CLASP N terminal Cut8_N PF14482.1 GAM20470.1 - 6.9 6.7 17.9 0.78 9.7 1.9 3.8 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Oxysterol_BP PF01237.13 GAM20471.1 - 1.3e-110 369.2 0.1 1.7e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein XPG_N PF00752.12 GAM20472.1 - 0.095 12.9 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 XPG N-terminal domain Myotub-related PF06602.9 GAM20473.1 - 2.8e-51 174.3 0.0 4.6e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 GAM20473.1 - 0.00046 19.6 0.2 0.0011 18.4 0.2 1.8 1 1 0 1 1 1 1 GRAM domain Sec1 PF00995.18 GAM20473.1 - 0.02 13.5 0.3 0.033 12.8 0.2 1.3 1 0 0 1 1 1 0 Sec1 family adh_short PF00106.20 GAM20475.1 - 8.6e-20 71.3 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM20475.1 - 5.2e-12 46.0 0.1 6.2e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM20475.1 - 9.8e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF2480 PF10652.4 GAM20475.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2480) adh_short PF00106.20 GAM20476.1 - 1.9e-30 105.9 0.1 3.4e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM20476.1 - 1.4e-14 54.4 0.1 1.9e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM20476.1 - 3.4e-12 46.4 0.0 5.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM20476.1 - 4.3e-07 29.6 0.1 1.3e-06 28.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM20476.1 - 7.1e-06 26.1 0.0 1.3e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM20476.1 - 0.0021 17.0 0.0 0.0032 16.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 GAM20476.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 GAM20476.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Chlam_PMP PF02415.12 GAM20477.1 - 7.5e-07 29.0 70.6 0.25 11.7 2.3 12.4 12 0 0 12 12 12 10 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Nol1_Nop2_Fmu PF01189.12 GAM20478.1 - 8.8e-22 77.7 0.1 3.5e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 GAM20478.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase NusB PF01029.13 GAM20478.1 - 0.071 13.0 1.3 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 NusB family MinE PF03776.9 GAM20480.1 - 2.5e-12 46.1 0.0 3.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DUF1957 PF09210.6 GAM20480.1 - 0.0091 16.0 0.1 0.016 15.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1957) MAP PF03642.8 GAM20480.1 - 0.085 13.0 0.2 0.12 12.5 0.2 1.4 1 1 0 1 1 1 0 MAP domain Trehalose_PPase PF02358.11 GAM20480.1 - 0.088 11.7 0.2 0.09 11.6 0.1 1.1 1 0 0 1 1 1 0 Trehalose-phosphatase BLOC1_2 PF10046.4 GAM20481.1 - 1.2e-29 102.3 4.3 2.3e-29 101.4 3.0 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 GAM20481.1 - 0.0056 15.2 2.4 0.0073 14.8 1.6 1.1 1 0 0 1 1 1 1 AAA domain V_ATPase_I PF01496.14 GAM20481.1 - 0.016 13.0 1.2 0.02 12.8 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 GAM20481.1 - 0.02 14.7 0.7 0.04 13.7 0.5 1.5 1 0 0 1 1 1 0 Tropomyosin like IFT20 PF14931.1 GAM20481.1 - 0.048 13.5 0.4 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Nsp1_C PF05064.8 GAM20481.1 - 0.056 13.0 3.3 0.046 13.3 1.0 1.8 1 1 0 1 1 1 0 Nsp1-like C-terminal region HSBP1 PF06825.7 GAM20481.1 - 0.061 12.9 1.4 0.53 9.8 0.3 2.7 2 1 0 2 2 2 0 Heat shock factor binding protein 1 LAGLIDADG_1 PF00961.14 GAM20481.1 - 0.087 13.3 0.7 0.17 12.4 0.3 1.6 1 1 0 1 1 1 0 LAGLIDADG endonuclease GCN5L1 PF06320.8 GAM20481.1 - 0.095 12.5 1.4 0.23 11.2 0.1 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) TBPIP PF07106.8 GAM20481.1 - 0.15 11.6 4.3 0.29 10.6 3.0 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2360 PF10152.4 GAM20481.1 - 0.19 12.0 13.5 0.085 13.1 5.0 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) IncA PF04156.9 GAM20481.1 - 0.46 10.0 5.2 3.9 7.0 3.7 1.9 1 1 1 2 2 2 0 IncA protein Mucin PF01456.12 GAM20481.1 - 5.3 6.8 16.7 1.8 8.3 3.9 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein ENTH PF01417.15 GAM20482.1 - 2.9e-18 65.9 1.4 1e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 ENTH domain DUF3453 PF11935.3 GAM20482.1 - 3.4e-05 23.3 1.1 9.8e-05 21.8 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3453) Alpha_adaptin_C PF02296.11 GAM20482.1 - 0.049 13.5 1.6 0.16 11.9 1.1 1.9 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Nup35_RRM PF05172.8 GAM20484.1 - 2.2e-09 36.9 0.0 1e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 GAM20484.1 - 0.0053 16.4 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif tRNA-synt_1e PF01406.14 GAM20485.1 - 6.5e-59 199.5 6.6 6.8e-40 137.0 2.5 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAM20485.1 - 0.0083 14.8 0.2 0.13 10.8 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (M) Clathrin PF00637.15 GAM20486.1 - 1.1e-24 86.6 25.1 8e-16 57.9 7.0 3.1 2 1 1 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.3 GAM20486.1 - 7.8e-17 60.8 0.5 4e-16 58.5 0.1 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal YPEB PF14620.1 GAM20486.1 - 0.0029 16.6 0.3 0.0072 15.3 0.0 1.7 2 0 0 2 2 2 1 YpeB sporulation TPR_11 PF13414.1 GAM20486.1 - 0.042 13.5 0.0 0.21 11.2 0.0 2.3 1 0 0 1 1 1 0 TPR repeat DUF1703 PF08011.6 GAM20488.1 - 0.014 15.1 1.8 3.3 7.4 1.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1703) His_Phos_2 PF00328.17 GAM20488.1 - 0.069 12.4 2.3 0.072 12.4 0.3 1.8 1 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Amidohydro_2 PF04909.9 GAM20489.1 - 1e-22 81.0 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase XPG_N PF00752.12 GAM20490.1 - 0.013 15.7 0.3 0.052 13.7 0.1 2.1 2 0 0 2 2 2 0 XPG N-terminal domain XPG_I PF00867.13 GAM20490.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 XPG I-region Pkinase_Tyr PF07714.12 GAM20491.1 - 3.4e-53 180.3 0.0 5.8e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM20491.1 - 3.1e-48 164.1 0.0 7.7e-48 162.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 GAM20491.1 - 6.5e-33 111.8 28.4 1.5e-12 46.7 2.6 7.8 4 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM20491.1 - 3.1e-29 100.4 27.1 1e-12 47.6 0.6 6.3 5 1 1 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 GAM20491.1 - 5.5e-18 62.2 20.3 0.058 13.4 0.0 10.5 9 1 0 9 9 9 5 Leucine Rich Repeat RhoGEF PF00621.15 GAM20491.1 - 5.8e-18 65.3 7.5 2.3e-15 56.9 2.2 3.0 1 1 0 2 2 2 2 RhoGEF domain Ras PF00071.17 GAM20491.1 - 3.2e-11 42.8 0.0 5.4e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 Ras family LRR_7 PF13504.1 GAM20491.1 - 4.7e-11 41.0 16.0 0.67 10.4 0.0 10.1 10 0 0 10 10 9 3 Leucine rich repeat Miro PF08477.8 GAM20491.1 - 2e-09 37.9 0.1 8.9e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein PH PF00169.24 GAM20491.1 - 8.9e-07 29.0 0.1 3.3e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 PH domain LRR_6 PF13516.1 GAM20491.1 - 0.00054 19.7 35.2 0.11 12.5 0.4 10.9 12 0 0 12 12 10 2 Leucine Rich repeat Peptidase_C1 PF00112.18 GAM20492.1 - 4.1e-73 245.8 10.7 6.1e-60 202.8 1.6 2.1 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM20492.1 - 4.4e-14 52.4 0.9 6.9e-14 51.8 0.6 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM20492.1 - 0.02 13.4 4.3 0.24 9.8 0.9 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Coiled PF05710.7 GAM20493.1 - 4.8e-12 46.1 27.2 5.5e-12 45.9 18.9 1.0 1 0 0 1 1 1 1 Coiled coil Fork_head_N PF08430.7 GAM20493.1 - 2.8 8.3 9.3 3.2 8.1 6.4 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region ubiquitin PF00240.18 GAM20494.1 - 1.7e-14 52.9 0.0 2e-05 23.8 0.0 4.0 3 0 0 3 3 3 2 Ubiquitin family A2M PF00207.17 GAM20494.1 - 2.8e-10 39.6 0.1 2.7e-09 36.4 0.0 2.7 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_N PF01835.14 GAM20494.1 - 1.7e-08 34.6 0.1 3.5e-07 30.4 0.0 3.4 4 0 0 4 4 4 1 MG2 domain Rad60-SLD PF11976.3 GAM20494.1 - 1.2e-07 31.3 0.0 0.00034 20.2 0.0 3.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like A2M_N_2 PF07703.9 GAM20494.1 - 1.3e-05 24.9 0.0 8.9e-05 22.3 0.0 2.6 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region Dioxygenase_C PF00775.16 GAM20494.1 - 0.041 13.1 0.2 0.22 10.7 0.0 2.3 3 0 0 3 3 3 0 Dioxygenase Prenyltrans_1 PF13243.1 GAM20494.1 - 0.14 12.1 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 Prenyltransferase-like UPF0253 PF06786.7 GAM20495.1 - 0.051 13.6 0.7 0.12 12.5 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) Duffy_binding PF05424.6 GAM20495.1 - 0.055 13.2 8.1 0.33 10.7 5.6 2.3 1 1 0 1 1 1 0 Duffy binding domain FNIP PF05725.7 GAM20496.1 - 4.4e-52 173.7 11.6 1.5e-16 60.0 0.3 9.2 7 3 3 10 10 10 8 FNIP Repeat LRR_6 PF13516.1 GAM20496.1 - 0.19 11.8 1.8 31 5.0 0.0 5.2 7 0 0 7 7 7 0 Leucine Rich repeat Endotoxin_N PF03945.9 GAM20497.1 - 1.9e-12 47.0 0.3 3.1e-12 46.3 0.2 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM20498.1 - 8.7e-17 61.2 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain CAP PF00188.21 GAM20499.1 - 4.3e-05 23.9 0.0 9.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GFA PF04828.9 GAM20500.1 - 1.2e-08 34.7 2.6 1.2e-08 34.7 1.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ecotin PF03974.8 GAM20501.1 - 2e-42 143.9 0.0 2.4e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Ecotin Lipase_GDSL PF00657.17 GAM20502.1 - 4e-08 33.3 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.12 GAM20502.1 - 7.2e-06 25.9 1.2 7.2e-06 25.9 0.8 2.2 2 0 0 2 2 2 1 Saposin-like type B, region 2 Cu-binding_MopE PF11617.3 GAM20502.1 - 0.037 13.8 3.0 0.12 12.1 2.1 1.9 1 0 0 1 1 1 0 Protein metal binding site VWA_2 PF13519.1 GAM20505.1 - 2.5e-19 70.0 0.0 5.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.18 GAM20505.1 - 4.4e-08 32.4 0.1 1.3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Ras PF00071.17 GAM20505.1 - 0.00023 20.5 0.1 0.00076 18.8 0.0 2.0 2 0 0 2 2 2 1 Ras family VWA_3 PF13768.1 GAM20505.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain CDP-OH_P_transf PF01066.16 GAM20506.1 - 1.8e-18 66.6 5.5 1.8e-18 66.6 3.8 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HILPDA PF15220.1 GAM20506.1 - 0.14 12.1 0.1 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated WH2 PF02205.15 GAM20507.1 - 0.014 14.9 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 0 WH2 motif PAT1 PF09770.4 GAM20507.1 - 0.9 7.7 20.1 1.1 7.3 13.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRCC PF10253.4 GAM20507.1 - 2.5 8.7 11.0 45 4.6 5.3 3.0 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting BAR PF03114.13 GAM20508.1 - 6.1e-17 61.8 18.0 7.4e-17 61.6 12.5 1.0 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 GAM20508.1 - 0.00016 20.7 15.4 0.00019 20.4 10.7 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.8 GAM20508.1 - 0.00036 19.9 16.1 0.00043 19.7 11.1 1.0 1 0 0 1 1 1 1 Arfaptin-like domain DUF1188 PF06690.6 GAM20508.1 - 0.026 13.6 0.1 0.044 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) PRD PF00874.15 GAM20508.1 - 0.97 9.5 4.7 5.4 7.2 0.9 2.5 2 0 0 2 2 2 0 PRD domain Ferritin-like PF12902.2 GAM20508.1 - 1.3 8.5 9.8 5.1 6.6 2.2 2.1 1 1 1 2 2 2 0 Ferritin-like DUF948 PF06103.6 GAM20508.1 - 3.2 7.6 5.0 4.5 7.2 0.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tho2 PF11262.3 GAM20508.1 - 3.7 6.5 11.3 0.45 9.5 2.9 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF904 PF06005.7 GAM20508.1 - 8.5 6.7 11.8 1.1 9.5 3.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) FKBP_C PF00254.23 GAM20509.1 - 2.6e-29 101.0 0.0 3.2e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-CDGSH PF09360.5 GAM20510.1 - 1.2e-26 92.2 5.3 1.6e-13 50.2 0.3 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Metallothio_Euk PF12749.2 GAM20510.1 - 0.46 10.5 5.4 8.7 6.4 0.3 2.1 1 1 0 2 2 2 0 Eukaryotic metallothionein Metallophos PF00149.23 GAM20511.1 - 7e-17 61.4 1.2 1.8e-16 60.1 0.9 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM20511.1 - 3e-13 49.6 0.9 3e-13 49.6 0.6 3.6 4 0 0 4 4 4 1 Iron/zinc purple acid phosphatase-like protein C BRO1 PF03097.13 GAM20512.1 - 2.4e-98 329.3 12.4 2.4e-98 329.3 8.6 2.8 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAM20512.1 - 1.4e-64 217.9 21.0 1.4e-64 217.9 14.6 3.1 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV E1-E2_ATPase PF00122.15 GAM20513.1 - 7.4e-59 198.5 0.8 7.4e-59 198.5 0.5 2.6 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM20513.1 - 3.9e-42 143.8 7.8 3.9e-42 143.8 5.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM20513.1 - 2.3e-26 93.5 0.1 1.2e-25 91.1 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM20513.1 - 2.3e-16 59.5 0.1 5.1e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAM20513.1 - 3.2e-14 52.1 0.2 1e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM20513.1 - 6.4e-14 52.5 0.0 1.4e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM20513.1 - 0.00011 21.9 0.5 0.016 14.7 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATP_Ca_trans_C PF12424.3 GAM20513.1 - 0.015 15.6 0.8 7.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Plasma membrane calcium transporter ATPase C terminal NfeD PF01957.13 GAM20513.1 - 0.037 14.1 0.1 0.037 14.1 0.1 2.9 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Dicty_REP PF05086.7 GAM20513.1 - 0.2 9.3 0.7 0.32 8.7 0.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein WW PF00397.21 GAM20514.1 - 5.8e-22 77.2 7.7 8e-11 41.6 1.0 2.6 2 0 0 2 2 2 2 WW domain C2 PF00168.25 GAM20514.1 - 1.4e-05 24.8 0.9 0.0021 17.8 0.2 2.6 2 0 0 2 2 2 2 C2 domain NT-C2 PF10358.4 GAM20514.1 - 0.00022 20.7 0.8 0.00053 19.4 0.6 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ACT_4 PF13291.1 GAM20514.1 - 0.35 11.2 3.5 0.19 12.1 0.3 2.1 3 0 0 3 3 3 0 ACT domain CLN5 PF15014.1 GAM20515.1 - 1.1e-13 51.2 4.9 1.4e-13 50.8 3.4 1.1 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 Man-6-P_recep PF02157.10 GAM20515.1 - 7e-05 21.9 0.1 0.00014 20.9 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 GAM20515.1 - 0.017 14.3 0.0 0.017 14.3 0.0 1.6 2 0 0 2 2 2 0 Autophagy-related protein 27 Ribosomal_L22 PF00237.14 GAM20516.1 - 1.7e-31 108.2 0.4 2e-31 108.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RNF111_N PF15303.1 GAM20516.1 - 0.11 12.0 1.1 0.16 11.4 0.8 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus ATG27 PF09451.5 GAM20517.1 - 5.1e-25 88.2 2.4 5.5e-24 84.8 1.7 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 GAM20517.1 - 5.4e-07 28.8 0.4 9.3e-07 28.1 0.3 1.4 1 1 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 GAM20517.1 - 1.3e-06 28.2 0.2 4e-06 26.6 0.3 1.7 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 GAM20517.1 - 0.0038 16.7 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF4175 PF13779.1 GAM20519.1 - 0.77 7.3 12.8 1.2 6.7 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Vma12 PF11712.3 GAM20519.1 - 4.2 7.0 5.5 97 2.6 3.0 2.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase UPF0160 PF03690.8 GAM20520.1 - 5e-122 407.2 0.0 5.6e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) NuA4 PF09340.5 GAM20521.1 - 1.5e-24 85.4 0.1 1.5e-24 85.4 0.1 1.9 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Sporozoite_P67 PF05642.6 GAM20521.1 - 0.01 13.7 1.5 0.011 13.6 1.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 GAM20521.1 - 0.23 11.2 11.4 0.35 10.6 7.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 GAM20521.1 - 1.7 8.4 8.9 2.7 7.7 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Upf2 PF04050.9 GAM20521.1 - 5.1 6.8 7.5 0.42 10.3 1.4 1.7 2 0 0 2 2 2 0 Up-frameshift suppressor 2 Rad51 PF08423.6 GAM20522.1 - 3.8e-16 58.7 0.1 1e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAM20522.1 - 2.8e-09 36.6 0.0 5.2e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM20522.1 - 3.3e-06 26.4 0.0 6.7e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 KaiC RecA PF00154.16 GAM20522.1 - 2.2e-05 23.6 0.0 7.8e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein CobU PF02283.11 GAM20522.1 - 6.2e-05 22.4 0.0 0.016 14.6 0.0 2.4 1 1 1 2 2 2 2 Cobinamide kinase / cobinamide phosphate guanyltransferase IPT PF01745.11 GAM20522.1 - 0.011 14.9 0.1 0.027 13.6 0.0 1.7 1 1 0 1 1 1 0 Isopentenyl transferase IstB_IS21 PF01695.12 GAM20522.1 - 0.013 14.8 0.2 0.19 11.1 0.0 2.6 2 1 0 2 2 2 0 IstB-like ATP binding protein DnaB_C PF03796.10 GAM20522.1 - 0.033 13.0 0.1 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA PF00004.24 GAM20522.1 - 0.15 12.3 0.1 0.77 9.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SF3a60_bindingd PF12108.3 GAM20522.1 - 0.38 10.3 2.8 5.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain ApoL PF05461.6 GAM20523.1 - 6.3e-05 22.3 0.1 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Apolipoprotein L zf-C3HC4_2 PF13923.1 GAM20523.1 - 0.08 12.9 0.8 0.08 12.9 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM20523.1 - 0.33 10.8 6.5 0.092 12.5 1.3 2.2 2 0 0 2 2 2 0 Ring finger domain Cpn60_TCP1 PF00118.19 GAM20525.1 - 1.1e-74 251.8 3.7 1.3e-74 251.6 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F5_F8_type_C PF00754.20 GAM20526.1 - 9.6e-19 67.4 0.1 1.8e-18 66.6 0.0 1.5 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 GAM20526.1 - 3.7e-17 61.7 0.1 7.5e-17 60.7 0.1 1.6 1 0 0 1 1 1 1 H-type lectin domain Hist_deacetyl PF00850.14 GAM20527.1 - 2e-91 306.5 2.1 3.7e-91 305.6 0.0 2.1 2 0 0 2 2 2 1 Histone deacetylase domain Xpo1 PF08389.7 GAM20528.1 - 5.9e-10 39.2 9.7 7.4e-09 35.6 0.2 4.9 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 GAM20528.1 - 0.0024 17.7 0.1 0.011 15.6 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ribosomal_L18e PF00828.14 GAM20529.1 - 9.1e-33 113.3 0.1 1.1e-32 113.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ank_2 PF12796.2 GAM20530.1 - 6.4e-61 202.7 18.3 1.5e-10 41.2 0.3 8.5 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20530.1 - 1e-40 137.4 11.7 6.5e-05 23.3 0.0 12.2 8 4 4 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20530.1 - 1e-38 130.4 18.8 0.0014 18.8 0.1 16.9 1 1 16 18 18 18 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20530.1 - 4.1e-31 103.9 15.7 0.027 14.7 0.0 17.6 10 3 9 19 19 19 5 Ankyrin repeat Ank PF00023.25 GAM20530.1 - 9e-30 100.9 18.1 0.022 14.5 0.0 17.4 15 2 4 19 19 19 9 Ankyrin repeat zf-4CXXC_R1 PF10497.4 GAM20530.1 - 0.0012 18.9 0.8 19 5.4 0.0 5.6 6 1 1 7 7 7 1 Zinc-finger domain of monoamine-oxidase A repressor R1 SDA1 PF05285.7 GAM20531.1 - 1 8.5 22.8 0.55 9.4 2.2 2.3 2 0 0 2 2 2 0 SDA1 Ribosomal_L5_C PF00673.16 GAM20532.1 - 3.3e-22 78.0 0.1 5e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAM20532.1 - 4.8e-18 64.6 0.3 2.9e-17 62.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 tRNA_anti-codon PF01336.20 GAM20533.1 - 0.039 13.8 0.1 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ribosomal_S19e PF01090.14 GAM20534.1 - 1.2e-51 173.8 0.1 1.4e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L21e PF01157.13 GAM20536.1 - 1.3e-36 124.3 5.1 2e-36 123.7 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Phosphoesterase PF04185.9 GAM20538.1 - 4.6e-71 239.9 2.9 4.6e-71 239.9 2.0 1.4 2 0 0 2 2 2 1 Phosphoesterase family Coiled PF05710.7 GAM20540.1 - 1.9 9.0 5.5 9.3 6.7 3.8 1.9 1 1 0 1 1 1 0 Coiled coil Kelch_3 PF13415.1 GAM20541.1 - 1.7e-35 120.3 17.4 4.4e-09 36.2 0.1 7.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM20541.1 - 6.1e-35 118.5 21.3 2.7e-09 36.3 0.2 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 GAM20541.1 - 1.2e-33 114.5 26.2 1.9e-08 34.0 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM20541.1 - 3e-31 106.2 20.3 2.1e-08 33.9 0.3 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.1 GAM20541.1 - 3e-31 106.9 16.0 7e-07 28.9 0.3 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM20541.1 - 9.6e-24 82.2 22.1 3.3e-07 29.8 0.3 6.7 6 0 0 6 6 6 6 Kelch motif F-box PF00646.28 GAM20541.1 - 2.3e-09 36.6 0.6 2.3e-09 36.6 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM20541.1 - 8.9e-08 31.7 0.1 2.4e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 GAM20541.1 - 0.024 14.6 1.2 0.072 13.0 0.9 1.8 1 0 0 1 1 1 0 PRANC domain DUF581 PF04570.9 GAM20541.1 - 0.11 11.7 0.1 3 7.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Macoilin PF09726.4 GAM20541.1 - 5 5.2 8.8 7.5 4.6 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein RasGEF PF00617.14 GAM20543.1 - 3.4e-31 108.4 1.7 3.4e-31 108.4 1.2 2.0 2 0 0 2 2 2 1 RasGEF domain RhoGAP PF00620.22 GAM20543.1 - 4.7e-15 55.5 0.1 1.4e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.15 GAM20543.1 - 7e-13 48.5 0.2 4.4e-12 46.0 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif Pribosyltran_N PF13793.1 GAM20544.1 - 8.6e-43 144.7 2.0 5e-42 142.3 0.1 2.6 3 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM20544.1 - 2.4e-30 105.6 5.2 1.4e-27 96.6 0.9 3.2 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM20544.1 - 0.026 14.2 1.1 0.05 13.3 0.3 1.9 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Spc7 PF08317.6 GAM20547.1 - 2.6e-07 29.6 6.7 2.6e-07 29.6 4.6 3.0 2 1 2 4 4 4 1 Spc7 kinetochore protein DUF4401 PF14351.1 GAM20548.1 - 0.00077 18.5 5.8 0.0011 18.1 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) COX15-CtaA PF02628.10 GAM20548.1 - 0.0018 17.1 0.1 0.0022 16.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Tmemb_9 PF05434.6 GAM20548.1 - 0.051 13.3 0.5 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 TMEM9 DUF1358 PF07096.6 GAM20548.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) GFA PF04828.9 GAM20549.1 - 0.0022 17.9 6.6 0.0043 16.9 4.6 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF3474 PF11960.3 GAM20549.1 - 0.09 12.7 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) ZZ PF00569.12 GAM20550.1 - 5.2e-05 22.6 6.9 0.00011 21.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Vps39_2 PF10367.4 GAM20550.1 - 0.0014 18.7 3.3 1.9 8.7 0.2 3.4 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 2 MTHFR PF02219.12 GAM20551.1 - 7.5e-118 392.7 0.0 1.7e-117 391.6 0.0 1.5 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Aconitase PF00330.15 GAM20552.1 - 4.8e-173 575.9 0.5 2e-172 573.8 0.2 2.1 2 1 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 GAM20552.1 - 1.8e-47 160.7 0.0 3.7e-47 159.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF4451 PF14616.1 GAM20552.1 - 0.088 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) ThiF PF00899.16 GAM20553.1 - 6.2e-50 168.5 1.5 2.6e-33 114.7 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 GAM20553.1 - 5.6e-24 84.6 0.0 1.4e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 GAM20553.1 - 1.5e-16 59.6 1.0 6.3e-13 48.1 0.0 3.5 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAM20553.1 - 9.1e-08 31.3 1.7 0.00054 19.2 0.5 2.8 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Inhibitor_I29 PF08246.7 GAM20554.1 - 8.6e-12 45.1 0.1 2.3e-11 43.7 0.0 1.8 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Gram_pos_anchor PF00746.16 GAM20554.1 - 6.8 6.6 13.5 3.2 7.6 2.7 2.5 1 1 1 2 2 2 0 Gram positive anchor DUF3042 PF11240.3 GAM20554.1 - 9.1 6.1 8.5 0.33 10.7 0.9 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3042) Peptidase_C1 PF00112.18 GAM20555.1 - 1.8e-49 168.5 8.5 4.2e-49 167.3 5.9 1.6 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.21 GAM20555.1 - 3.3e-14 53.4 2.8 3.3e-14 53.4 1.9 2.6 2 1 1 3 3 3 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.10 GAM20555.1 - 0.0011 17.6 0.2 0.85 8.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family TFIIA PF03153.8 GAM20555.1 - 0.64 9.8 5.5 0.92 9.3 3.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_TAF50 PF03326.8 GAM20555.1 - 2.2 7.1 19.5 3.8 6.3 13.5 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PAP1 PF08601.5 GAM20555.1 - 2.5 7.7 14.8 3.8 7.1 10.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PIH1 PF08190.7 GAM20555.1 - 6.2 6.1 7.1 9.3 5.5 4.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Xpo1 PF08389.7 GAM20557.1 - 9.9e-12 45.0 1.0 9.9e-12 45.0 0.7 5.2 5 2 1 6 6 6 1 Exportin 1-like protein Complex1_LYR_1 PF13232.1 GAM20558.1 - 1.1e-06 28.7 0.8 6.7e-06 26.2 0.6 2.2 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM20558.1 - 1.1e-06 28.2 0.4 4.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 GAM20558.1 - 0.00078 19.8 0.1 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RRM_1 PF00076.17 GAM20559.1 - 2.6e-17 62.2 0.0 4.7e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20559.1 - 1.7e-11 43.8 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20559.1 - 4.7e-10 39.1 0.0 8.9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DRY_EERY PF09750.4 GAM20560.1 - 0.042 13.9 5.1 0.044 13.8 3.5 1.0 1 0 0 1 1 1 0 Alternative splicing regulator Activator_LAG-3 PF11498.3 GAM20560.1 - 6.9 5.2 21.9 6.6 5.3 15.2 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA PF00004.24 GAM20563.1 - 2.2e-14 53.7 0.0 8.1e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM20563.1 - 1.3e-13 51.1 0.0 3.6e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM20563.1 - 3e-11 43.6 0.0 7.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.6 GAM20563.1 - 0.00069 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 CDC6, C terminal NACHT PF05729.7 GAM20563.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 GAM20563.1 - 0.0028 17.3 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 GAM20563.1 - 0.0045 16.5 0.1 0.0045 16.5 0.0 2.3 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.17 GAM20563.1 - 0.013 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 GAM20563.1 - 0.033 14.0 0.2 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAM20563.1 - 0.037 13.7 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 GAM20563.1 - 0.085 12.4 3.1 1.7 8.3 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 GAM20563.1 - 0.12 12.5 1.9 0.2 11.8 0.0 2.4 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.1 GAM20563.1 - 0.72 10.6 0.0 0.72 10.6 0.0 3.7 3 1 0 3 3 2 0 AAA domain Nrap PF03813.9 GAM20564.1 - 2.2e-155 518.7 7.6 1.8e-133 446.2 2.3 2.2 2 0 0 2 2 2 2 Nrap protein Daxx PF03344.10 GAM20564.1 - 3.7 5.9 13.4 6.3 5.1 9.3 1.2 1 0 0 1 1 1 0 Daxx Family Cob_adeno_trans PF01923.13 GAM20565.1 - 4.5e-50 169.6 0.0 5.3e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DTW PF03942.10 GAM20566.1 - 7.4e-25 87.3 1.0 1.7e-24 86.2 0.7 1.6 1 1 0 1 1 1 1 DTW domain DUF4347 PF14252.1 GAM20566.1 - 0.041 13.3 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) AAA_12 PF13087.1 GAM20567.1 - 3.2e-45 153.9 0.4 6.2e-45 153.0 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM20567.1 - 1.5e-27 96.6 6.1 8.2e-27 94.2 4.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAM20567.1 - 1.2e-08 34.7 0.1 0.00095 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 GAM20567.1 - 1.3e-07 30.9 0.6 8.5e-06 24.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 GAM20567.1 - 3.7e-07 29.8 0.0 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 GAM20567.1 - 0.00022 21.3 0.0 0.02 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 GAM20567.1 - 0.00092 18.4 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 GAM20567.1 - 0.0037 17.4 0.2 0.043 14.0 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAM20567.1 - 0.0055 16.1 0.0 0.021 14.2 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 GAM20567.1 - 0.012 15.5 0.0 0.03 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 GAM20567.1 - 0.025 14.4 0.0 0.13 12.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM20567.1 - 0.034 13.5 0.0 0.083 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM20567.1 - 0.035 14.9 0.3 1.4 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 GAM20567.1 - 0.037 13.8 1.4 0.081 12.7 0.0 2.3 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 GAM20567.1 - 0.082 12.5 0.0 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 GAM20567.1 - 0.097 12.4 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.2 GAM20568.1 - 2.6e-29 101.4 3.0 1.8e-16 60.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM20568.1 - 2.3e-28 96.5 0.6 1.5e-07 30.9 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM20568.1 - 3.8e-24 84.5 3.6 1.1e-07 32.1 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20568.1 - 4.2e-22 76.0 1.1 0.00011 22.1 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 GAM20568.1 - 2.4e-18 65.7 1.2 4.8e-06 26.6 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) RabGAP-TBC PF00566.13 GAM20569.1 - 2.8e-36 125.0 5.6 4.1e-35 121.1 3.9 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain OSCP PF00213.13 GAM20570.1 - 7.1e-15 55.2 3.5 7.4e-15 55.2 0.1 2.1 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit DUF2362 PF10154.4 GAM20570.1 - 0.012 14.3 0.7 0.012 14.3 0.5 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2362) Baculo_p26 PF04766.7 GAM20571.1 - 0.067 12.4 0.3 0.084 12.1 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein Pex14_N PF04695.8 GAM20571.1 - 2 8.4 6.8 14 5.6 4.7 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3678 PF12435.3 GAM20571.1 - 2.9 7.5 8.5 21 4.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) SAICAR_synt PF01259.13 GAM20572.1 - 1.3e-60 204.6 0.5 1.5e-60 204.3 0.4 1.0 1 0 0 1 1 1 1 SAICAR synthetase Cation_efflux PF01545.16 GAM20574.1 - 2.9e-62 210.3 6.0 3.3e-62 210.1 4.1 1.0 1 0 0 1 1 1 1 Cation efflux family ERCC4 PF02732.10 GAM20575.1 - 0.00011 22.0 0.1 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain MaoC_dehydratas PF01575.14 GAM20576.1 - 4.8e-28 96.9 0.0 2.4e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAM20576.1 - 2e-12 47.0 0.0 1e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FKBP_C PF00254.23 GAM20577.1 - 6.8e-14 51.6 0.0 7.7e-10 38.6 0.0 2.5 3 0 0 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 GAM20577.1 - 3.4e-10 39.4 0.6 8.7e-05 22.0 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM20577.1 - 1.1e-07 31.1 1.7 0.00069 19.1 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20577.1 - 2.2e-07 30.2 1.6 0.0017 18.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20577.1 - 2.2e-06 27.8 1.1 0.00067 20.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM20577.1 - 0.0011 19.2 1.1 0.66 10.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 GAM20577.1 - 0.0018 18.0 0.2 0.0037 17.1 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.1 GAM20577.1 - 0.0023 18.5 1.6 0.46 11.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM20577.1 - 0.013 15.3 0.0 0.04 13.7 0.0 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 GAM20577.1 - 0.018 15.3 0.6 0.14 12.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM20577.1 - 0.068 13.3 1.0 1.2 9.2 0.4 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HgmA PF04209.8 GAM20578.1 - 3.8e-194 644.9 0.1 4.4e-194 644.7 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ank_2 PF12796.2 GAM20580.1 - 5.3e-09 36.3 2.0 0.009 16.3 0.3 5.0 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20580.1 - 0.00014 21.7 3.6 2.5 8.5 0.0 6.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 GAM20580.1 - 0.00043 20.4 0.5 9.4 6.6 0.0 5.9 5 2 1 6 6 6 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20580.1 - 0.0021 18.5 4.2 1.3 9.5 0.0 5.6 6 2 1 7 7 7 1 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM20580.1 - 0.0027 17.4 6.1 0.16 11.8 0.4 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF3447) zf-CCCH PF00642.19 GAM20581.1 - 1.1e-05 24.9 0.5 1.1e-05 24.9 0.4 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SR-25 PF10500.4 GAM20582.1 - 0.016 14.6 6.2 0.018 14.5 4.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BLOC1_2 PF10046.4 GAM20582.1 - 0.018 15.1 0.6 0.018 15.1 0.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3839 PF12943.2 GAM20582.1 - 0.13 11.3 3.1 0.061 12.4 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3839) RNA_pol_Rpb1_5 PF04998.12 GAM20582.1 - 0.7 9.1 5.7 0.79 8.9 3.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Pyridoxal_deC PF00282.14 GAM20583.1 - 1.7e-18 66.2 0.0 4.2e-18 64.9 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAM20583.1 - 1.5e-16 60.1 0.0 5e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM20583.1 - 9.5e-05 21.5 0.1 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAM20583.1 - 0.0034 15.7 0.0 0.0052 15.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Phosphoesterase PF04185.9 GAM20584.1 - 1e-87 294.7 4.7 1.4e-87 294.3 3.3 1.1 1 0 0 1 1 1 1 Phosphoesterase family Tom22 PF04281.8 GAM20585.1 - 0.13 11.7 5.2 0.32 10.5 3.6 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4175 PF13779.1 GAM20585.1 - 0.4 8.3 14.7 0.51 7.9 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Myotub-related PF06602.9 GAM20586.1 - 2.2e-119 398.3 0.0 4.6e-119 397.3 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PX PF00787.19 GAM20586.1 - 4.5e-16 58.6 0.2 2.1e-15 56.5 0.1 2.2 1 0 0 1 1 1 1 PX domain PH PF00169.24 GAM20586.1 - 6.8e-11 42.3 0.6 3.1e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 PH domain Y_phosphatase3 PF13350.1 GAM20586.1 - 6.6e-05 23.2 0.0 0.00023 21.4 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 GAM20586.1 - 0.0013 18.3 0.0 0.0077 15.8 0.0 2.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM20586.1 - 0.0041 16.4 2.9 0.005 16.2 0.0 2.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Syntaxin_2 PF14523.1 GAM20587.1 - 6e-15 55.1 12.0 6e-15 55.1 8.3 2.2 2 1 0 2 2 2 1 Syntaxin-like protein DUF1727 PF08353.5 GAM20587.1 - 0.0067 16.0 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1727) Syntaxin_2 PF14523.1 GAM20588.1 - 7.1e-20 70.9 7.0 7.1e-20 70.9 4.9 2.8 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 GAM20588.1 - 2.1e-18 65.7 3.5 2.1e-18 65.7 2.4 2.3 3 0 0 3 3 3 1 SNARE domain PLDc_N PF13396.1 GAM20588.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF4064 PF13273.1 GAM20588.1 - 0.072 13.1 0.4 0.17 12.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3753 PF12575.3 GAM20588.1 - 0.1 12.4 0.2 0.26 11.1 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) AAA_13 PF13166.1 GAM20588.1 - 0.13 10.6 13.2 0.092 11.1 2.5 2.0 2 0 0 2 2 2 0 AAA domain NYD-SP28 PF14772.1 GAM20588.1 - 2.4 8.2 12.0 0.47 10.5 3.1 2.9 2 1 1 3 3 3 0 Sperm tail TMPIT PF07851.8 GAM20588.1 - 8 5.4 8.4 0.22 10.5 0.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein Spectrin PF00435.16 GAM20588.1 - 8.7 6.6 10.3 2.8 8.2 1.4 3.0 2 1 1 3 3 3 0 Spectrin repeat AT_hook PF02178.14 GAM20589.1 - 0.0034 16.8 3.6 0.012 15.1 2.5 2.0 1 0 0 1 1 1 1 AT hook motif Ank PF00023.25 GAM20590.1 - 1.1e-40 135.4 0.2 2.3e-09 36.5 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 GAM20590.1 - 6.1e-37 125.8 0.0 6.2e-16 58.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20590.1 - 5.1e-34 115.5 1.8 1.6e-09 37.6 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 GAM20590.1 - 2.3e-32 111.7 10.8 2.3e-32 111.7 7.5 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.1 GAM20590.1 - 3.6e-31 106.9 0.9 5.7e-11 42.6 0.0 5.4 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20590.1 - 5.9e-29 97.2 2.9 2e-06 27.4 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat MRAP PF15183.1 GAM20590.1 - 4.3 7.0 7.4 16 5.1 0.1 3.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family PRA1 PF03208.14 GAM20591.1 - 1.5e-23 82.8 9.7 8.1e-23 80.4 6.7 1.9 1 1 0 1 1 1 1 PRA1 family protein DUF295 PF03478.13 GAM20591.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF295) DUF1418 PF07214.7 GAM20591.1 - 0.07 12.7 1.5 0.12 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) RRM_1 PF00076.17 GAM20592.1 - 0.00022 20.7 0.0 0.00045 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20592.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EGF_2 PF07974.8 GAM20593.1 - 0.18 11.9 15.2 0.53 10.4 10.5 1.8 1 0 0 1 1 1 0 EGF-like domain Toxin_2 PF00451.14 GAM20593.1 - 0.25 11.4 8.7 0.59 10.2 6.0 1.6 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 CD36 PF01130.16 GAM20594.1 - 5.2e-24 84.3 0.6 7.6e-12 44.2 0.0 3.1 2 2 0 2 2 2 2 CD36 family Ank_2 PF12796.2 GAM20595.1 - 2.5e-14 53.3 0.8 4.9e-09 36.4 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20595.1 - 7.8e-10 38.6 4.9 0.0059 16.8 0.1 5.6 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20595.1 - 2.6e-09 37.3 6.1 4.4e-06 27.0 0.1 5.1 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20595.1 - 4.6e-07 29.4 3.0 5.2 7.6 0.0 6.1 4 2 2 6 6 6 3 Ankyrin repeat Ank PF00023.25 GAM20595.1 - 4.8e-06 26.1 0.4 8.4 6.4 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeat DDE_Tnp_4 PF13359.1 GAM20597.1 - 3.6e-15 55.9 0.3 8.2e-14 51.5 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM20597.1 - 1.1e-05 25.1 1.6 1.5e-05 24.6 1.1 1.3 1 1 0 1 1 1 1 Transposase DDE domain YjgF_endoribonc PF14588.1 GAM20598.1 - 4.1e-25 88.4 0.0 4.6e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 GAM20598.1 - 1.7e-13 50.4 0.0 2.7e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP DUF1275 PF06912.6 GAM20598.1 - 0.09 11.9 0.2 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DSPc PF00782.15 GAM20599.1 - 1.8e-25 89.0 0.1 6.4e-25 87.2 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.17 GAM20599.1 - 1.6e-12 46.9 1.3 0.00015 21.4 0.0 4.9 4 0 0 4 4 4 3 Gelsolin repeat 7TM-7TMR_HD PF07698.6 GAM20600.1 - 0.13 11.6 4.9 0.17 11.3 3.4 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Herpes_LMP1 PF05297.6 GAM20600.1 - 0.91 8.3 5.4 1.1 8.1 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF21 PF01595.15 GAM20600.1 - 8.2 5.6 11.2 22 4.2 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF21 EGF_2 PF07974.8 GAM20601.1 - 0.002 18.2 11.3 0.002 18.2 7.8 2.1 2 0 0 2 2 2 1 EGF-like domain Toxin_2 PF00451.14 GAM20601.1 - 0.019 15.0 2.3 0.044 13.8 1.6 1.6 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 EGF PF00008.22 GAM20601.1 - 0.092 12.7 8.3 0.23 11.4 5.8 1.7 1 0 0 1 1 1 0 EGF-like domain DUF1191 PF06697.7 GAM20601.1 - 0.11 11.3 0.2 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 GAM20601.1 - 0.16 12.3 0.4 0.3 11.5 0.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EB PF01683.13 GAM20601.1 - 0.5 10.4 5.7 1.1 9.3 4.0 1.6 1 0 0 1 1 1 0 EB module DUF2887 PF11103.3 GAM20602.1 - 0.022 14.3 0.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2887) ICAT PF06384.6 GAM20603.1 - 2.3e-23 81.7 1.5 4.7e-23 80.7 1.1 1.5 1 0 0 1 1 1 1 Beta-catenin-interacting protein ICAT GvpG PF05120.7 GAM20603.1 - 0.014 15.2 0.6 0.014 15.2 0.4 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Cortex-I_coil PF09304.5 GAM20603.1 - 0.02 14.8 1.7 0.02 14.8 1.2 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF3313 PF11769.3 GAM20603.1 - 0.028 13.7 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Syntaxin-18_N PF10496.4 GAM20603.1 - 0.053 13.3 0.2 0.096 12.5 0.2 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus WHEP-TRS PF00458.15 GAM20603.1 - 0.088 12.4 0.5 0.25 11.0 0.3 1.8 1 0 0 1 1 1 0 WHEP-TRS domain Abhydrolase_6 PF12697.2 GAM20604.1 - 1.4e-19 70.9 0.0 5.3e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM20604.1 - 1.5e-12 47.5 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 GAM20604.1 - 5.8e-05 22.6 0.1 0.00011 21.8 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 GAM20604.1 - 0.00039 20.0 0.1 0.0019 17.7 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM20604.1 - 0.008 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 GAM20604.1 - 0.03 13.2 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF900 PF05990.7 GAM20604.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DAGK_cat PF00781.19 GAM20605.1 - 1.3e-21 76.3 0.0 2.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FHA PF00498.21 GAM20606.1 - 3.6e-13 49.4 0.6 8.3e-13 48.2 0.4 1.7 1 0 0 1 1 1 1 FHA domain F-box-like PF12937.2 GAM20607.1 - 1e-09 37.9 0.3 2.3e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM20607.1 - 2.9e-07 29.9 0.7 5.3e-07 29.1 0.5 1.4 1 0 0 1 1 1 1 F-box domain ThuA PF06283.6 GAM20607.1 - 0.0056 16.4 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose utilisation DUF1355 PF07090.6 GAM20607.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1355) HIG_1_N PF04588.8 GAM20609.1 - 4.2e-09 36.0 1.5 5.5e-09 35.6 1.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CRAL_TRIO_N PF03765.10 GAM20609.1 - 0.046 13.8 0.8 0.13 12.4 0.1 2.2 3 1 0 3 3 3 0 CRAL/TRIO, N-terminal domain Lum_binding PF00677.12 GAM20609.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lumazine binding domain Gpi1 PF05024.10 GAM20610.1 - 2.6e-53 180.5 13.6 5.6e-53 179.4 9.4 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) IBR PF01485.16 GAM20611.1 - 4.9e-22 77.5 28.4 2.7e-13 49.5 3.8 3.8 3 1 0 3 3 3 2 IBR domain UBA PF00627.26 GAM20611.1 - 0.00024 20.8 0.1 0.00094 18.9 0.1 2.1 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_4 PF14570.1 GAM20611.1 - 0.0059 16.1 3.2 0.0059 16.1 2.2 3.8 3 1 1 4 4 4 1 RING/Ubox like zinc-binding domain Dicty_REP PF05086.7 GAM20611.1 - 0.015 13.0 6.0 0.026 12.2 4.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_2 PF13639.1 GAM20611.1 - 1.7 8.5 49.1 0.076 12.8 10.5 4.1 1 1 2 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.1 GAM20611.1 - 2.9 7.9 47.2 0.062 13.3 9.2 4.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cnd1_N PF12922.2 GAM20611.1 - 3.2 7.3 7.9 11 5.5 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term OTU PF02338.14 GAM20612.1 - 8.4e-21 74.7 0.3 8.4e-21 74.7 0.2 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease UBA PF00627.26 GAM20612.1 - 4.2e-05 23.2 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_C65 PF10275.4 GAM20612.1 - 6.6e-05 22.3 10.9 0.014 14.7 1.2 3.1 2 2 1 3 3 3 2 Peptidase C65 Otubain Mucin PF01456.12 GAM20612.1 - 0.037 13.8 10.8 0.074 12.8 7.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 GAM20612.1 - 0.046 11.7 9.5 0.07 11.1 6.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Presenilin PF01080.12 GAM20612.1 - 0.33 9.7 10.3 0.57 8.9 7.2 1.3 1 0 0 1 1 1 0 Presenilin FNIP PF05725.7 GAM20614.1 - 5.7e-46 154.2 28.9 8e-10 38.5 0.0 9.3 3 2 6 10 10 10 10 FNIP Repeat Pex2_Pex12 PF04757.9 GAM20614.1 - 9e-30 103.7 7.5 2.2e-28 99.2 5.2 2.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region NGP1NT PF08153.7 GAM20615.1 - 2e-41 140.9 0.1 2e-41 140.9 0.1 2.4 2 1 0 2 2 2 1 NGP1NT (NUC091) domain Beta-lactamase PF00144.19 GAM20616.1 - 9e-43 146.5 0.0 1.2e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase PARP PF00644.15 GAM20617.1 - 2.5e-23 82.6 0.7 7.2e-23 81.0 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 GAM20617.1 - 5.3e-09 35.3 4.6 0.00015 21.1 0.0 3.3 3 0 0 3 3 3 2 WWE domain Helitron_like_N PF14214.1 GAM20617.1 - 0.011 15.4 0.2 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Mucin PF01456.12 GAM20617.1 - 5 6.9 42.9 2.1 8.1 5.2 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein CactinC_cactus PF09732.4 GAM20619.1 - 7.3e-57 190.3 5.7 1.5e-56 189.3 4.0 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 GAM20619.1 - 3.7e-48 163.3 1.5 3.7e-48 163.3 1.0 2.7 2 1 0 2 2 2 1 Conserved mid region of cactin Band_7 PF01145.20 GAM20621.1 - 5.9e-09 36.0 1.0 5.9e-09 36.0 0.7 2.2 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 GAM20621.1 - 0.00028 20.4 0.3 0.00051 19.6 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Cullin PF00888.17 GAM20622.1 - 1.4e-198 661.2 16.5 2.1e-198 660.6 11.5 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAM20622.1 - 3.6e-30 103.6 5.1 1.2e-29 101.8 3.6 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Pkinase PF00069.20 GAM20623.1 - 9e-47 159.3 0.0 9e-47 159.3 0.0 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20623.1 - 5.9e-18 64.8 10.5 6.2e-18 64.7 0.0 3.9 3 1 0 3 3 3 1 Protein tyrosine kinase Choline_kinase PF01633.15 GAM20623.1 - 0.0014 18.2 0.2 0.0014 18.2 0.1 3.5 4 0 0 4 4 4 1 Choline/ethanolamine kinase APH PF01636.18 GAM20623.1 - 0.0084 15.8 0.3 0.0084 15.8 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4061 PF13270.1 GAM20624.1 - 0.00034 20.6 2.9 0.055 13.5 0.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4061) UBA_e1_C PF09358.5 GAM20624.1 - 0.023 14.8 1.1 0.028 14.5 0.8 1.1 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Alpha_kinase PF02816.13 GAM20626.1 - 1.9e-58 197.2 0.5 1.9e-58 197.2 0.3 2.6 2 0 0 2 2 2 1 Alpha-kinase family SHOCT PF09851.4 GAM20626.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain Pribosyl_synth PF14572.1 GAM20626.1 - 0.23 11.1 2.5 0.77 9.4 1.7 1.9 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain ArfGap PF01412.13 GAM20627.1 - 8.7e-22 77.0 0.1 2.5e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf TraV PF09676.5 GAM20627.1 - 0.024 15.3 2.5 0.081 13.6 1.8 1.9 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF3439 PF11921.3 GAM20627.1 - 0.054 13.2 0.1 0.054 13.2 0.1 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) DUF605 PF04652.11 GAM20627.1 - 0.26 10.6 18.4 0.35 10.2 12.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF2802 PF10975.3 GAM20627.1 - 2.3 8.0 9.3 4.2 7.1 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) PhnA_Zn_Ribbon PF08274.7 GAM20627.1 - 6.3 6.6 6.6 33 4.3 4.6 2.0 1 1 0 1 1 1 0 PhnA Zinc-Ribbon zf-B_box PF00643.19 GAM20627.1 - 8.4 6.3 7.3 2.2 8.2 2.2 2.0 2 0 0 2 2 2 0 B-box zinc finger DUF3825 PF12873.2 GAM20628.1 - 3.9e-31 108.0 0.0 3.9e-31 108.0 0.0 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3825) Cytochrom_C PF00034.16 GAM20629.1 - 2.1e-12 47.6 0.1 3.4e-12 47.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 GAM20629.1 - 3.1e-08 33.6 0.8 7.6e-08 32.4 0.5 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 GAM20629.1 - 8.3e-05 22.0 0.1 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain ketoacyl-synt PF00109.21 GAM20630.1 - 7.9e-74 248.3 0.0 1.8e-73 247.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM20630.1 - 2.1e-59 201.4 0.0 3.4e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Chal_sti_synt_N PF00195.14 GAM20630.1 - 6.6e-43 146.5 0.0 1.1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain KR PF08659.5 GAM20630.1 - 5.1e-41 140.3 0.0 2.6e-40 138.0 0.0 2.4 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 GAM20630.1 - 1.1e-38 131.7 3.2 2.5e-38 130.5 0.1 3.1 4 0 0 4 4 4 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 GAM20630.1 - 9.9e-34 116.8 0.0 1.7e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM20630.1 - 4e-32 111.4 0.1 4e-31 108.1 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Chal_sti_synt_C PF02797.10 GAM20630.1 - 2.1e-18 66.7 0.0 6.8e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain Methyltransf_12 PF08242.7 GAM20630.1 - 7.7e-17 61.5 0.1 1.3e-15 57.6 0.0 3.2 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM20630.1 - 1.3e-12 47.7 0.0 6.4e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.7 GAM20630.1 - 3e-12 46.2 0.2 3e-12 46.2 0.2 1.8 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ADH_zinc_N_2 PF13602.1 GAM20630.1 - 1.8e-11 45.0 0.0 5.5e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 GAM20630.1 - 4e-08 33.6 0.0 2.4e-07 31.1 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 GAM20630.1 - 6.1e-07 29.6 0.4 4.6e-06 26.8 0.0 2.7 3 0 0 3 3 2 1 Phosphopantetheine attachment site ACP_syn_III_C PF08541.5 GAM20630.1 - 1.6e-06 28.0 0.0 5.2e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_N PF08240.7 GAM20630.1 - 4.9e-06 26.2 0.1 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 GAM20630.1 - 1.4e-05 25.6 0.0 0.00053 20.5 0.0 3.5 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM20630.1 - 2.6e-05 23.8 0.0 0.00056 19.5 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 GAM20630.1 - 3.5e-05 22.9 0.2 9.9e-05 21.4 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM20630.1 - 7.9e-05 22.2 4.2 0.0013 18.3 0.2 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 GAM20630.1 - 0.0015 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase AMP-binding PF00501.23 GAM20631.1 - 1.4e-83 280.5 0.1 1.7e-83 280.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM20631.1 - 1.5e-17 64.3 0.1 3.6e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Enoyl_reductase PF12241.3 GAM20631.1 - 0.0056 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Trans-2-enoyl-CoA reductase catalytic region BTB_2 PF02214.17 GAM20632.1 - 6.3e-17 61.5 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.1 GAM20632.1 - 8.7e-16 57.4 42.6 2e-07 30.7 7.5 3.3 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 GAM20632.1 - 4.4e-14 51.3 10.8 5.7e-06 25.4 0.0 4.8 1 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 GAM20632.1 - 5.9e-12 45.2 28.5 6.6e-05 22.7 3.4 4.7 2 2 2 4 4 4 4 Pentapeptide repeats (9 copies) CfAFP PF05264.6 GAM20632.1 - 0.0084 15.8 10.5 0.015 15.0 6.7 1.9 1 1 0 1 1 1 1 Choristoneura fumiferana antifreeze protein (CfAFP) BTB PF00651.26 GAM20632.1 - 0.029 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain PhyH PF05721.8 GAM20633.1 - 1.1e-08 35.4 0.1 2.1e-07 31.2 0.1 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.11 GAM20633.1 - 0.0037 16.9 0.4 0.63 9.6 0.1 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_5 PF13759.1 GAM20633.1 - 0.018 15.3 0.2 0.31 11.3 0.1 2.3 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase DNA_pol3_delta2 PF13177.1 GAM20634.1 - 8.8e-15 54.7 0.0 5.9e-14 52.0 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 GAM20634.1 - 5.7e-14 52.4 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 GAM20634.1 - 7.9e-14 51.4 0.0 1.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 GAM20634.1 - 7.4e-09 34.8 0.0 2.4e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 GAM20634.1 - 1.8e-06 28.0 0.1 0.001 19.1 0.0 3.0 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 GAM20634.1 - 2.4e-06 27.7 0.0 1.6e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM20634.1 - 1.8e-05 24.4 0.0 3.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 GAM20634.1 - 4.7e-05 22.5 0.0 9.1e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 GAM20634.1 - 0.0002 21.0 0.0 0.0011 18.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain ResIII PF04851.10 GAM20634.1 - 0.00029 20.7 0.0 0.01 15.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 GAM20634.1 - 0.00067 18.8 0.0 0.006 15.7 0.0 2.1 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAM20634.1 - 0.0007 19.5 0.0 0.0016 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAM20634.1 - 0.00081 19.0 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 GAM20634.1 - 0.0022 17.2 0.0 0.27 10.4 0.0 2.6 1 1 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.1 GAM20634.1 - 0.0036 16.9 0.1 0.008 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAM20634.1 - 0.0096 15.6 0.1 0.033 13.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 GAM20634.1 - 0.015 14.7 0.2 0.32 10.4 0.0 2.5 2 1 1 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.8 GAM20634.1 - 0.018 13.9 0.0 0.043 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 GAM20634.1 - 0.021 14.2 0.2 0.058 12.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 GAM20634.1 - 0.026 13.5 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 GAM20634.1 - 0.04 13.3 0.2 1.4 8.3 0.1 2.8 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 GAM20634.1 - 0.055 13.1 0.0 0.088 12.4 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 GAM20634.1 - 0.089 12.2 0.1 0.87 8.9 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.1 GAM20634.1 - 0.11 12.8 0.0 0.38 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rif1_N PF12231.3 GAM20635.1 - 8.5e-40 136.8 5.5 1.5e-38 132.7 3.8 2.5 1 1 0 1 1 1 1 Rap1-interacting factor 1 N terminal WD40 PF00400.27 GAM20636.1 - 2.3e-44 147.7 14.6 2.1e-07 30.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 GAM20636.1 - 6.5e-35 119.6 0.7 6.5e-35 119.6 0.5 1.8 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 GAM20636.1 - 6.1e-28 97.3 10.6 9.5e-28 96.7 7.3 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 GAM20636.1 - 0.0051 16.5 0.0 15 5.4 0.0 3.7 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region UPF0203 PF05254.7 GAM20637.1 - 0.048 13.5 1.7 3.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) SNF2_N PF00176.18 GAM20640.1 - 3e-38 131.3 0.2 5.7e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM20640.1 - 2.3e-09 36.9 0.1 5.7e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Secretin_N_2 PF07655.8 GAM20640.1 - 0.15 12.4 23.2 1.2 9.6 8.8 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain SNF2_N PF00176.18 GAM20641.1 - 2.5e-08 33.0 0.4 4.6e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain TraA PF05513.6 GAM20642.1 - 0.15 12.2 7.3 0.95 9.6 5.6 1.8 2 0 0 2 2 2 0 TraA Asn_synthase PF00733.16 GAM20643.1 - 3e-73 246.4 0.1 4e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 GAM20643.1 - 2.1e-40 137.2 0.0 3.9e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 GAM20643.1 - 2e-28 98.9 0.0 4.5e-28 97.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 GAM20643.1 - 1.3e-16 60.4 0.2 2.2e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 GAM20643.1 - 5.9e-08 31.8 0.0 0.078 11.6 0.0 3.2 1 1 2 3 3 3 3 Glutamine amidotransferases class-II NAD_synthase PF02540.12 GAM20643.1 - 0.056 12.3 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.11 GAM20643.1 - 0.12 10.8 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Pectate_lyase_3 PF12708.2 GAM20644.1 - 9e-19 68.4 25.0 5.5e-18 65.9 12.5 3.0 1 1 1 2 2 2 1 Pectate lyase superfamily protein RNB PF00773.14 GAM20645.1 - 6.1e-58 196.6 0.7 1.2e-57 195.6 0.5 1.4 1 0 0 1 1 1 1 RNB domain CLTH PF10607.4 GAM20646.1 - 1e-31 109.5 0.8 1e-31 109.5 0.5 2.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 GAM20646.1 - 1.4e-06 27.8 0.8 4.7e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 GAM20646.1 - 0.0015 18.4 0.4 0.031 14.2 0.0 3.0 3 0 0 3 3 3 1 U-box domain Mitofilin PF09731.4 GAM20646.1 - 0.0018 17.0 5.5 0.0028 16.3 3.8 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein NIT PF08376.5 GAM20646.1 - 0.005 16.3 1.0 0.0087 15.6 0.7 1.3 1 0 0 1 1 1 1 Nitrate and nitrite sensing DUF3482 PF11981.3 GAM20646.1 - 0.022 13.9 0.6 0.041 13.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) LisH PF08513.6 GAM20646.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 LisH zf-RING_2 PF13639.1 GAM20646.1 - 0.05 13.4 0.2 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain DUF342 PF03961.8 GAM20646.1 - 0.086 11.2 4.3 0.16 10.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF883 PF05957.8 GAM20646.1 - 0.16 12.3 2.1 0.31 11.4 1.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Myb_DNA-bind_3 PF12776.2 GAM20646.1 - 0.29 11.7 4.1 0.34 11.5 1.3 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-RING_3 PF14369.1 GAM20646.1 - 0.58 10.2 2.2 31 4.6 0.0 2.7 2 0 0 2 2 2 0 zinc-finger ZapA PF05164.8 GAM20646.1 - 1.1 9.2 4.6 1.1 9.2 2.1 2.0 2 0 0 2 2 2 0 Cell division protein ZapA Occludin_ELL PF07303.8 GAM20646.1 - 1.2 9.9 7.6 0.75 10.5 3.2 2.2 2 1 1 3 3 2 0 Occludin homology domain DUF948 PF06103.6 GAM20646.1 - 1.6 8.6 4.8 4.8 7.1 3.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RhoGEF PF00621.15 GAM20647.1 - 1.1e-76 256.7 22.0 7.3e-48 162.8 3.0 3.3 3 0 0 3 3 3 2 RhoGEF domain RhoGAP PF00620.22 GAM20647.1 - 3.1e-45 153.5 1.7 1.5e-44 151.2 0.4 2.4 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 GAM20647.1 - 6.3e-14 51.2 0.0 1.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM20647.1 - 7.5e-12 44.4 0.0 2.3e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 GAM20647.1 - 6.9e-09 35.0 0.0 1.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 GAM20647.1 - 1.3e-07 31.7 0.3 1.3e-07 31.7 0.2 2.8 4 0 0 4 4 4 1 PH domain RNA_pol_Rpa2_4 PF06883.7 GAM20648.1 - 0.12 12.3 0.0 0.43 10.5 0.0 2.0 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain SH3_9 PF14604.1 GAM20651.1 - 1.1e-21 76.1 0.0 1.6e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAM20651.1 - 3.9e-20 70.9 0.1 7e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAM20651.1 - 3.3e-18 64.9 0.0 1.4e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SF-assemblin PF06705.6 GAM20651.1 - 0.025 13.7 1.2 0.092 11.8 0.6 1.9 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF3104 PF11302.3 GAM20651.1 - 0.12 11.7 0.1 7.1 6.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) RRM_1 PF00076.17 GAM20652.1 - 9.4e-30 102.0 0.0 7e-14 51.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20652.1 - 3.8e-21 74.6 1.3 4.6e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20652.1 - 6.5e-18 64.4 0.2 9.6e-10 38.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.1 GAM20652.1 - 0.0035 17.6 2.1 0.0035 17.6 1.4 3.5 3 0 0 3 3 3 1 AAA domain Band_7 PF01145.20 GAM20653.1 - 2.1e-32 112.4 4.5 3.7e-32 111.6 3.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family U3_assoc_6 PF08640.6 GAM20653.1 - 0.028 14.1 3.0 0.12 12.1 0.5 2.7 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Band_7_1 PF13421.1 GAM20653.1 - 0.035 13.6 0.4 0.035 13.6 0.3 1.8 2 1 0 2 2 2 0 SPFH domain-Band 7 family Coatomer_WDAD PF04053.9 GAM20654.1 - 1.2e-121 406.6 1.0 3e-121 405.3 0.1 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 GAM20654.1 - 3.9e-113 378.1 0.0 5.5e-113 377.6 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 GAM20654.1 - 4.2e-53 175.4 9.5 2.8e-11 42.8 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM20654.1 - 0.0034 15.5 4.0 0.0091 14.1 0.5 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF1921 PF09081.5 GAM20654.1 - 0.14 12.1 0.3 0.71 9.8 0.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) HTH_9 PF08221.6 GAM20655.1 - 1.4e-12 47.2 2.5 7.9e-08 32.0 0.4 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 GAM20655.1 - 6.4e-06 25.8 8.5 0.0072 15.8 5.6 3.5 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 GAM20655.1 - 0.015 14.7 3.1 0.073 12.5 0.2 3.2 3 0 0 3 3 3 0 TFIIE alpha subunit Sel1 PF08238.7 GAM20656.1 - 1.9e-26 91.8 27.0 8e-05 23.1 0.1 10.2 10 0 0 10 10 10 5 Sel1 repeat DUF2785 PF10978.3 GAM20656.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) Raptor_N PF14538.1 GAM20656.1 - 0.088 12.6 1.1 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Uma2 PF05685.7 GAM20657.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative restriction endonuclease Pro-kuma_activ PF09286.6 GAM20662.1 - 3.7e-34 117.8 0.1 6.1e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM20662.1 - 4.7e-08 32.5 2.0 9.6e-08 31.5 1.4 1.4 1 0 0 1 1 1 1 Subtilase family Lipase_3 PF01764.20 GAM20663.1 - 2.7e-15 56.1 0.0 3.7e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM20663.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF912 PF06024.7 GAM20664.1 - 0.63 10.1 2.9 0.59 10.2 0.1 2.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cellulase PF00150.13 GAM20665.1 - 7e-28 97.6 0.2 1.1e-27 96.9 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M20 PF01546.23 GAM20666.1 - 3.4e-31 108.2 0.0 4.5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM20666.1 - 4.4e-20 71.4 0.0 7.9e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM20666.1 - 8.3e-05 22.4 0.0 0.00021 21.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 GAM20666.1 - 0.032 12.9 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase UPF0172 PF03665.8 GAM20666.1 - 0.064 12.7 0.1 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) COX14 PF14880.1 GAM20667.1 - 6.4e-06 25.7 1.8 1.2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1364 PF07102.7 GAM20667.1 - 0.029 14.2 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) DUF2570 PF10828.3 GAM20667.1 - 0.044 13.3 0.2 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF2804 PF10974.3 GAM20667.1 - 0.073 11.9 0.0 0.076 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Nic96 PF04097.9 GAM20668.1 - 1.8e-67 227.8 9.5 9.6e-67 225.4 6.6 2.0 1 1 0 1 1 1 1 Nup93/Nic96 TPR_3 PF07720.7 GAM20668.1 - 0.19 11.5 0.0 0.19 11.5 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20668.1 - 0.25 11.3 6.4 5.3 7.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20668.1 - 0.37 10.4 4.2 7.4 6.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Thioredoxin PF00085.15 GAM20669.1 - 1.8e-23 82.1 0.4 2.4e-18 65.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 GAM20669.1 - 3.3e-08 33.7 0.3 3.6e-06 27.1 0.1 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM20669.1 - 0.00055 20.0 0.9 7.1 6.8 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like HyaE PF07449.6 GAM20669.1 - 0.016 15.1 0.0 2.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE ThiF PF00899.16 GAM20671.1 - 1.1e-35 122.4 0.0 2.3e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 GAM20671.1 - 0.0011 19.1 0.1 0.0047 17.1 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Glutaredoxin PF00462.19 GAM20671.1 - 0.023 14.6 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin HNF-1_N PF04814.8 GAM20671.1 - 0.047 13.7 0.6 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Saccharop_dh PF03435.13 GAM20671.1 - 0.049 12.6 0.0 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 GAM20671.1 - 0.062 13.4 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TFIIE-A_C-term PF11521.3 GAM20671.1 - 0.23 11.3 4.8 0.085 12.8 1.1 1.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Cullin PF00888.17 GAM20672.1 - 4.3e-11 42.0 0.0 4.8e-11 41.9 0.0 1.0 1 0 0 1 1 1 1 Cullin family DnaI_N PF07319.6 GAM20672.1 - 0.0018 18.5 0.0 0.0039 17.3 0.0 1.5 2 0 0 2 2 2 1 Primosomal protein DnaI N-terminus KfrA_N PF11740.3 GAM20672.1 - 0.057 13.8 0.0 0.075 13.4 0.0 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Cullin PF00888.17 GAM20673.1 - 1.5e-72 244.9 12.5 2e-72 244.6 8.7 1.0 1 0 0 1 1 1 1 Cullin family HsdM_N PF12161.3 GAM20674.1 - 0.024 15.0 0.3 0.051 13.9 0.2 1.5 1 0 0 1 1 1 0 HsdM N-terminal domain Hemerythrin PF01814.18 GAM20674.1 - 0.099 12.7 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Vfa1 PF08432.5 GAM20675.1 - 0.013 15.4 2.3 0.017 15.1 1.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 GAM20675.1 - 0.32 10.3 9.7 0.39 10.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 GAM20675.1 - 0.37 8.7 16.3 0.44 8.5 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2796 PF10986.3 GAM20675.1 - 0.69 9.8 10.0 0.81 9.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) BUD22 PF09073.5 GAM20675.1 - 1.2 8.1 14.8 1.2 8.1 10.3 1.0 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 GAM20675.1 - 2.1 7.4 14.9 2.7 7.1 10.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Dicty_REP PF05086.7 GAM20675.1 - 3.7 5.1 10.8 4.3 4.9 7.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2457 PF10446.4 GAM20675.1 - 3.9 6.0 44.0 4.9 5.7 30.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 GAM20675.1 - 4.4 6.4 22.1 5.1 6.2 15.3 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 GAM20675.1 - 4.9 4.9 26.5 5.6 4.7 18.4 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM20675.1 - 7.7 4.8 20.5 8.8 4.6 14.2 1.0 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 GAM20675.1 - 9.1 4.2 11.2 11 3.9 7.8 1.1 1 0 0 1 1 1 0 Utp14 protein FNIP PF05725.7 GAM20677.1 - 1.7e-69 229.5 6.9 1.8e-10 40.5 0.2 7.5 5 2 3 8 8 8 8 FNIP Repeat Glyco_hydro_4C PF11975.3 GAM20677.1 - 1.5 8.5 5.4 2.7e+02 1.1 0.0 5.9 7 1 1 8 8 8 0 Family 4 glycosyl hydrolase C-terminal domain Biopterin_H PF00351.16 GAM20678.1 - 6e-164 544.5 0.0 7.4e-164 544.3 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 GAM20678.1 - 9.3e-05 21.8 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 GAM20678.1 - 0.035 14.4 0.6 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 ACT domain DUF1903 PF08991.5 GAM20679.1 - 0.0026 17.9 3.7 0.0026 17.9 2.6 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 GAM20679.1 - 0.032 14.1 1.6 0.032 14.1 1.1 2.1 2 0 0 2 2 2 0 CHCH domain TFIIS_C PF01096.13 GAM20680.1 - 7.6e-11 41.4 7.4 1.7e-10 40.3 1.7 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 GAM20680.1 - 2.5e-05 24.4 2.6 0.0008 19.6 0.9 2.1 2 0 0 2 2 2 1 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 GAM20680.1 - 0.0028 16.9 10.7 0.011 15.0 2.8 2.8 2 2 1 3 3 3 1 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 GAM20680.1 - 0.06 13.1 9.3 0.098 12.4 0.1 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF3268 PF11672.3 GAM20680.1 - 0.19 11.8 2.0 2.8 8.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Elf1 PF05129.8 GAM20680.1 - 0.56 9.9 5.4 1.2 8.8 0.5 2.2 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Ribosomal_L44 PF00935.14 GAM20680.1 - 1.5 8.9 6.6 3.9 7.5 0.1 2.4 2 1 1 3 3 3 0 Ribosomal protein L44 PhnA_Zn_Ribbon PF08274.7 GAM20680.1 - 1.8 8.4 5.8 0.28 10.9 0.7 2.1 2 1 0 2 2 2 0 PhnA Zinc-Ribbon DUF2387 PF09526.5 GAM20680.1 - 1.8 8.5 6.7 11 6.0 0.1 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.5 GAM20680.1 - 4.5 7.3 10.2 6 6.8 0.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-DNL PF05180.7 GAM20680.1 - 7.1 6.4 8.4 15 5.4 0.7 2.8 3 0 0 3 3 3 0 DNL zinc finger zf-ribbon_3 PF13248.1 GAM20680.1 - 7.6 5.8 8.7 3.5 6.9 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbon domain CBFD_NFYB_HMF PF00808.18 GAM20681.1 - 1.1e-07 31.8 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM20681.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3260 PF11658.3 GAM20681.1 - 0.068 11.3 4.9 0.087 10.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) BTV_NS2 PF04514.7 GAM20681.1 - 0.22 10.3 7.6 0.31 9.8 5.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Med15 PF09606.5 GAM20681.1 - 0.25 9.4 22.3 0.28 9.3 15.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FYDLN_acid PF09538.5 GAM20681.1 - 0.86 10.2 6.8 1.5 9.4 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pex14_N PF04695.8 GAM20681.1 - 1.3 9.0 14.7 1.5 8.8 9.6 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bud13 PF09736.4 GAM20681.1 - 5.5 7.2 14.2 7.8 6.7 9.8 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex eIF-3_zeta PF05091.7 GAM20682.1 - 3 6.3 17.3 4.3 5.8 12.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NUMOD3 PF07460.6 GAM20684.1 - 0.036 13.9 0.1 0.036 13.9 0.1 3.5 3 0 0 3 3 3 0 NUMOD3 motif (2 copies) RhoGAP PF00620.22 GAM20685.1 - 1.6e-35 121.9 1.0 3.8e-35 120.7 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.15 GAM20685.1 - 3.7e-32 111.6 5.1 4.4e-31 108.1 0.5 2.8 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM20685.1 - 5.6e-19 68.2 2.7 6.1e-16 58.5 0.9 2.6 2 0 0 2 2 2 2 PH domain IMD PF08397.6 GAM20685.1 - 0.0019 17.5 0.5 0.0019 17.5 0.4 2.4 1 1 1 2 2 2 1 IRSp53/MIM homology domain PH_11 PF15413.1 GAM20685.1 - 0.0026 17.9 6.2 0.016 15.4 2.5 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 GAM20685.1 - 0.072 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_25 PF13481.1 GAM20688.1 - 9.6e-21 74.0 0.0 1.8e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_4 PF13662.1 GAM20688.1 - 3.8e-10 39.6 0.0 8.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.1 GAM20688.1 - 1e-08 35.3 0.0 3.9e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.1 GAM20688.1 - 4.8e-08 33.2 0.1 1.6e-06 28.3 0.0 3.2 3 0 0 3 3 3 1 Toprim-like AAA_22 PF13401.1 GAM20688.1 - 5.4e-08 33.0 0.0 2e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 GAM20688.1 - 5.8e-05 22.1 0.0 0.00015 20.7 0.0 1.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain KaiC PF06745.8 GAM20688.1 - 0.00011 21.3 0.1 0.00021 20.4 0.1 1.3 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 GAM20688.1 - 0.0081 15.3 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM20688.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_16 PF13191.1 GAM20688.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 GAM20688.1 - 0.016 14.7 2.0 0.082 12.4 0.1 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain Toprim PF01751.17 GAM20688.1 - 0.016 15.1 0.1 0.18 11.8 0.0 2.6 2 1 0 2 2 2 0 Toprim domain T2SE PF00437.15 GAM20688.1 - 0.02 13.7 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 GAM20688.1 - 0.036 13.4 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 GAM20688.1 - 0.046 14.0 0.4 0.046 14.0 0.3 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 GAM20688.1 - 0.047 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.1 GAM20688.1 - 0.054 14.3 0.4 0.47 11.2 0.1 2.8 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 GAM20688.1 - 0.074 12.9 0.2 0.3 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM20688.1 - 0.088 12.4 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TFIIF_alpha PF05793.7 GAM20688.1 - 4.3 5.5 10.6 7.9 4.7 7.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Y_phosphatase PF00102.22 GAM20689.1 - 1.6e-75 253.4 0.3 2.3e-75 252.9 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM20689.1 - 2.9e-07 30.1 0.0 9.1e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM20689.1 - 6.5e-06 26.2 0.0 2.2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAM20689.1 - 0.0007 19.8 0.0 0.0031 17.7 0.0 1.9 1 1 1 3 3 3 1 Tyrosine phosphatase family PSS PF03034.10 GAM20690.1 - 2.7e-116 387.9 10.4 4.2e-116 387.2 7.2 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF962 PF06127.6 GAM20690.1 - 0.033 14.0 1.6 2.1 8.3 1.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF106 PF01956.11 GAM20690.1 - 0.087 12.3 1.8 0.092 12.2 0.1 2.0 2 1 0 2 2 2 0 Integral membrane protein DUF106 zf-C2H2_2 PF12756.2 GAM20691.1 - 0.043 13.9 0.6 0.043 13.9 0.4 2.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 GAM20691.1 - 0.21 11.9 2.3 8.7 6.9 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 GAM20691.1 - 3.4 8.1 7.1 10 6.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 GAM20691.1 - 4.6 7.7 9.8 0.87 10.0 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type CTD_bind PF04818.8 GAM20692.1 - 0.0004 20.5 0.1 0.001 19.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 GAM20692.1 - 0.0031 17.1 0.1 0.0068 16.0 0.0 1.6 1 1 0 1 1 1 1 VHS domain TruD PF01142.13 GAM20693.1 - 5.3e-56 189.9 0.2 1.2e-53 182.1 0.0 3.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) bZIP_1 PF00170.16 GAM20694.1 - 1.9e-11 43.7 10.3 1.9e-11 43.7 7.1 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM20694.1 - 2.5e-09 36.8 7.4 2.5e-09 36.8 5.2 3.6 3 1 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM20694.1 - 0.00014 22.1 8.5 0.00014 22.1 5.9 2.8 3 0 0 3 3 3 1 bZIP Maf transcription factor ChaC PF04752.7 GAM20695.1 - 3.7e-54 183.3 0.0 5e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein PUA PF01472.15 GAM20695.1 - 6.5e-18 64.2 0.1 1.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 PUA domain AIG2 PF06094.7 GAM20695.1 - 0.046 14.2 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 AIG2-like family SET PF00856.23 GAM20696.1 - 1.6e-11 44.7 1.2 1.8e-10 41.3 0.8 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 GAM20696.1 - 0.015 15.1 9.7 0.015 15.1 6.7 2.8 3 1 0 3 3 3 0 MYND finger TGT PF01702.13 GAM20697.1 - 2.2e-51 174.4 0.0 3.1e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Tyr-DNA_phospho PF06087.7 GAM20697.1 - 0.006 15.2 0.6 0.011 14.4 0.4 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase TIP120 PF08623.5 GAM20698.1 - 1.7e-49 167.6 17.3 6.6e-48 162.4 0.0 5.6 7 0 0 7 7 7 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 GAM20698.1 - 4.8e-19 68.4 0.9 0.1 12.8 0.0 9.0 6 3 3 9 9 9 6 HEAT repeats HEAT PF02985.17 GAM20698.1 - 1.9e-15 55.4 12.4 0.14 12.2 0.0 12.5 14 0 0 14 14 14 4 HEAT repeat HEAT_EZ PF13513.1 GAM20698.1 - 1e-13 51.3 7.3 1.4 9.4 0.0 11.5 11 2 2 13 13 13 3 HEAT-like repeat Arm PF00514.18 GAM20698.1 - 4.8e-05 23.0 4.0 7.2 6.6 0.0 6.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 GAM20698.1 - 0.00047 20.0 3.0 1 9.3 0.1 5.4 2 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation V-ATPase_H_C PF11698.3 GAM20698.1 - 0.00052 19.9 2.5 14 5.5 0.1 5.9 6 0 0 6 6 6 1 V-ATPase subunit H CDC45 PF02724.9 GAM20698.1 - 0.0013 16.8 1.7 0.0022 16.1 1.2 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF1546 PF07571.8 GAM20698.1 - 0.014 15.4 0.2 19 5.4 0.0 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1546) DUF2457 PF10446.4 GAM20698.1 - 9.4 4.8 14.5 14 4.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prp18 PF02840.10 GAM20699.1 - 3.4e-57 192.3 0.3 3.4e-57 192.3 0.2 2.5 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 GAM20699.1 - 1.7e-10 39.9 2.8 4e-10 38.7 2.0 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Aldo_ket_red PF00248.16 GAM20700.1 - 8.8e-54 182.2 0.0 1.1e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ARID PF01388.16 GAM20703.1 - 3.5e-10 39.5 0.0 8.2e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain SH2_2 PF14633.1 GAM20704.1 - 4.8e-50 169.6 1.7 1.2e-49 168.3 1.1 1.7 1 0 0 1 1 1 1 SH2 domain AAA PF00004.24 GAM20704.1 - 9e-49 165.0 0.0 8.5e-31 106.8 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) DLD PF14878.1 GAM20704.1 - 4.8e-24 84.6 2.6 4.9e-24 84.6 0.0 2.5 2 0 0 2 2 1 1 Death-like domain of SPT6 HHH_7 PF14635.1 GAM20704.1 - 2.8e-21 75.5 0.3 7.5e-21 74.2 0.2 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 GAM20704.1 - 6e-20 71.3 0.0 1.7e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 GAM20704.1 - 3.7e-15 55.9 2.5 1.3e-14 54.2 1.8 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 GAM20704.1 - 2.7e-07 30.2 0.0 0.0013 18.5 0.0 2.8 2 0 0 2 2 2 2 SH2 domain AAA_22 PF13401.1 GAM20704.1 - 3.6e-07 30.3 0.0 0.053 13.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 GAM20704.1 - 1.6e-06 28.2 3.8 0.021 14.8 0.4 4.2 2 2 0 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.16 GAM20704.1 - 3e-06 26.5 0.0 0.0024 17.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAM20704.1 - 8.2e-05 22.1 0.0 0.54 9.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.1 GAM20704.1 - 0.0016 18.3 0.1 0.95 9.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 GAM20704.1 - 0.0017 17.3 0.0 0.61 8.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAM20704.1 - 0.0024 18.1 5.9 0.98 9.7 0.0 3.9 3 0 0 3 3 2 2 ABC transporter AAA_5 PF07728.9 GAM20704.1 - 0.0025 17.5 0.0 0.69 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 GAM20704.1 - 0.0025 16.5 0.0 0.042 12.5 0.0 2.6 3 0 0 3 3 3 1 TIP49 C-terminus RNA_helicase PF00910.17 GAM20704.1 - 0.0088 16.2 0.0 3.7 7.7 0.0 3.5 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 GAM20704.1 - 0.018 14.0 0.1 0.39 9.7 0.0 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 GAM20704.1 - 0.038 13.6 0.3 4.4 6.9 0.1 3.6 3 2 0 3 3 2 0 NACHT domain IstB_IS21 PF01695.12 GAM20704.1 - 0.041 13.3 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 GAM20704.1 - 0.088 12.3 0.1 14 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 GAM20704.1 - 0.17 11.6 0.3 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 GAM20704.1 - 0.42 11.4 0.0 0.42 11.4 0.0 4.4 5 1 0 5 5 1 0 AAA domain AAA_25 PF13481.1 GAM20704.1 - 1.6 8.0 3.0 12 5.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain LRR_4 PF12799.2 GAM20705.1 - 9.4e-32 108.1 47.1 4.8e-07 29.2 0.0 8.2 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM20705.1 - 1.3e-31 108.1 68.3 6.3e-08 32.2 0.6 6.4 2 2 7 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 GAM20705.1 - 6.5e-23 77.2 44.4 0.011 15.6 0.0 12.7 12 1 0 12 12 12 9 Leucine Rich Repeat LRR_7 PF13504.1 GAM20705.1 - 5.9e-17 58.7 33.9 0.1 12.8 0.0 12.2 12 0 0 12 12 12 6 Leucine rich repeat Filamin PF00630.14 GAM20705.1 - 4.6e-10 39.9 0.1 7e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat LRR_6 PF13516.1 GAM20705.1 - 1.1e-09 37.2 41.6 0.38 10.9 0.1 11.3 10 1 1 11 11 11 6 Leucine Rich repeat Abhydrolase_6 PF12697.2 GAM20707.1 - 3e-27 95.9 0.0 3.5e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM20707.1 - 1.9e-22 79.5 2.2 2.2e-21 76.1 1.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 GAM20707.1 - 0.001 18.7 0.1 0.0031 17.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.15 GAM20707.1 - 0.094 12.2 1.0 3.8 7.0 0.2 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold FliH PF02108.11 GAM20708.1 - 0.014 15.2 1.7 0.17 11.7 0.0 3.3 3 0 0 3 3 3 0 Flagellar assembly protein FliH Sod_Ni PF09055.6 GAM20708.1 - 0.087 13.2 4.8 0.058 13.7 0.9 2.6 3 0 0 3 3 3 0 Nickel-containing superoxide dismutase Peptidase_C50 PF03568.12 GAM20709.1 - 1.1e-65 221.7 0.0 1.1e-65 221.7 0.0 3.1 3 0 0 3 3 3 1 Peptidase family C50 TPR_12 PF13424.1 GAM20709.1 - 1.7e-10 40.6 18.4 8.9e-05 22.3 0.0 7.2 6 1 2 8 8 8 3 Tetratricopeptide repeat CHAT PF12770.2 GAM20709.1 - 5.1e-06 25.8 0.0 0.00014 21.1 0.0 2.5 1 1 0 1 1 1 1 CHAT domain TPR_2 PF07719.12 GAM20709.1 - 8.2e-06 25.3 7.9 0.59 10.1 0.1 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM20709.1 - 0.00018 21.0 9.4 0.12 12.0 0.0 6.3 5 1 0 5 5 5 1 TPR repeat TPR_6 PF13174.1 GAM20709.1 - 0.49 10.9 9.1 5.4 7.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Secretin_N_2 PF07655.8 GAM20709.1 - 7.5 7.0 24.5 0.1 12.9 11.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain RVT_1 PF00078.22 GAM20710.1 - 1.9e-33 115.6 0.0 2.8e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 GAM20711.1 - 9.6e-20 69.6 4.5 7e-07 28.8 0.3 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L30 PF00327.15 GAM20711.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e CAP_C PF08603.6 GAM20713.1 - 7e-08 31.9 2.5 1.2e-07 31.2 1.5 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal SEC-C PF02810.10 GAM20713.1 - 2.1e-05 23.9 14.1 3.7e-05 23.1 9.7 1.4 1 0 0 1 1 1 1 SEC-C motif Big_1 PF02369.11 GAM20713.1 - 0.024 14.5 0.6 0.059 13.2 0.4 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Peptidase_S28 PF05577.7 GAM20714.1 - 2.1e-79 267.1 0.2 2.5e-79 266.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 GAM20714.1 - 4.6e-08 32.8 0.0 8.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.6 GAM20714.1 - 4e-07 28.8 0.0 6.9e-06 24.7 0.0 2.0 2 0 0 2 2 2 1 PS-10 peptidase S37 Abhydrolase_6 PF12697.2 GAM20714.1 - 4.3e-07 30.0 0.0 2e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM20714.1 - 3.3e-06 26.9 0.0 7.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM20714.1 - 0.00038 19.7 0.0 0.0036 16.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family WD40 PF00400.27 GAM20715.1 - 5.8e-55 181.3 18.6 3.5e-07 29.8 0.0 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 GAM20715.1 - 8.9e-09 35.3 0.5 0.003 17.3 0.1 5.2 2 1 3 5 5 5 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 GAM20715.1 - 0.03 12.1 0.7 4.3 5.0 0.1 2.8 3 0 0 3 3 3 0 IKI3 family Nup160 PF11715.3 GAM20715.1 - 0.074 11.1 10.9 0.24 9.4 0.2 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 COPI_assoc PF08507.5 GAM20716.1 - 4.2e-23 81.5 19.3 4.7e-23 81.3 13.4 1.0 1 0 0 1 1 1 1 COPI associated protein FBPase PF00316.15 GAM20717.1 - 3.9e-120 400.5 0.0 4.5e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 GAM20717.1 - 0.011 15.0 0.0 0.081 12.2 0.0 2.2 3 0 0 3 3 3 0 Inositol monophosphatase family YjgP_YjgQ PF03739.9 GAM20718.1 - 0.011 14.5 0.2 0.017 13.8 0.1 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family EB PF01683.13 GAM20718.1 - 0.019 15.0 4.2 0.061 13.3 2.9 1.8 1 0 0 1 1 1 0 EB module EGF_2 PF07974.8 GAM20718.1 - 1.7 8.8 14.3 4.4 7.5 9.9 1.8 1 0 0 1 1 1 0 EGF-like domain Acyl_transf_3 PF01757.17 GAM20720.1 - 1.6e-30 106.1 40.8 2.7e-30 105.3 28.3 1.3 1 0 0 1 1 1 1 Acyltransferase family CH PF00307.26 GAM20722.1 - 5.1e-13 48.9 0.5 5.1e-13 48.9 0.3 2.0 2 1 0 2 2 2 1 Calponin homology (CH) domain Pex14_N PF04695.8 GAM20722.1 - 0.0037 17.3 4.9 0.18 11.8 1.9 2.4 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region CAMSAP_CH PF11971.3 GAM20722.1 - 0.022 14.3 1.6 0.033 13.8 0.1 2.1 2 0 0 2 2 2 0 CAMSAP CH domain Sporozoite_P67 PF05642.6 GAM20722.1 - 0.53 8.0 15.0 0.16 9.8 8.4 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF3439 PF11921.3 GAM20722.1 - 7.3 6.3 14.0 6.3 6.5 4.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LIM PF00412.17 GAM20723.1 - 1.1e-12 47.7 8.8 2.3e-12 46.7 6.1 1.6 1 0 0 1 1 1 1 LIM domain Baculo_PEP_C PF04513.7 GAM20723.1 - 0.026 14.3 46.9 0.11 12.2 5.0 6.4 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 GAM20724.1 - 3.4e-63 213.2 0.0 4.2e-61 206.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20724.1 - 7.9e-29 100.4 0.2 7.5e-20 71.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM20724.1 - 6.5e-05 22.0 0.0 0.18 10.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 GAM20724.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20724.1 - 0.015 15.0 0.1 0.29 10.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM20724.1 - 0.026 14.1 2.5 0.029 13.9 0.0 2.3 3 0 0 3 3 3 0 Choline/ethanolamine kinase Cation_efflux PF01545.16 GAM20725.1 - 1.1e-40 139.4 5.0 1.5e-40 139.0 3.4 1.1 1 0 0 1 1 1 1 Cation efflux family Myb_DNA-binding PF00249.26 GAM20726.1 - 3.1e-11 43.1 0.1 5.8e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Acyltransferase PF01553.16 GAM20727.1 - 1.5e-05 24.4 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MpPF26 PF07666.6 GAM20727.1 - 4.6 7.1 12.4 8 6.3 8.6 1.3 1 0 0 1 1 1 0 M penetrans paralogue family 26 YtzH PF14165.1 GAM20728.1 - 0.014 15.6 11.3 0.062 13.5 0.0 4.1 3 1 1 4 4 4 0 YtzH-like protein Inhibitor_I36 PF03995.8 GAM20728.1 - 0.023 15.0 1.0 0.074 13.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 DUF2430 PF10353.4 GAM20728.1 - 0.11 12.7 0.1 0.35 11.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2430) Tropomyosin_1 PF12718.2 GAM20728.1 - 2.2 8.1 8.8 0.2 11.5 2.5 1.9 2 0 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.4 GAM20728.1 - 2.7 8.2 8.9 0.16 12.1 0.5 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hemerythrin PF01814.18 GAM20729.1 - 1.5e-08 34.8 10.3 5.5e-08 33.0 4.0 1.5 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF4404 PF14357.1 GAM20729.1 - 0.058 13.8 2.0 0.18 12.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) SWIM PF04434.12 GAM20730.1 - 0.035 13.5 0.1 0.078 12.4 0.1 1.6 1 0 0 1 1 1 0 SWIM zinc finger Abhydrolase_3 PF07859.8 GAM20731.1 - 1.2e-66 224.2 0.1 1.2e-66 224.2 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold FYVE PF01363.16 GAM20731.1 - 5.4e-20 71.0 12.0 5.4e-20 71.0 8.3 2.2 3 0 0 3 3 2 1 FYVE zinc finger COesterase PF00135.23 GAM20731.1 - 3.2e-12 45.9 0.9 9.2e-12 44.4 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAM20731.1 - 0.00019 20.7 1.5 0.00079 18.7 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM20731.1 - 0.00099 18.8 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 GAM20731.1 - 0.004 15.8 2.2 0.0049 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 GAM20731.1 - 0.0097 14.4 0.0 0.1 11.0 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) AUX_IAA PF02309.11 GAM20731.1 - 0.091 12.4 7.0 0.14 11.8 4.8 1.2 1 0 0 1 1 1 0 AUX/IAA family DLH PF01738.13 GAM20731.1 - 0.71 9.1 0.0 0.71 9.1 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family zf-C3HC4_2 PF13923.1 GAM20731.1 - 9.9 6.2 14.0 1.9e+02 2.1 10.0 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM20731.1 - 10 5.9 13.5 1.4e+02 2.2 9.7 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ArfGap PF01412.13 GAM20732.1 - 3.3e-36 123.6 0.0 5.3e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 GAM20732.1 - 3.7e-17 62.4 0.2 6e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM20732.1 - 4.2e-08 33.4 1.9 2e-06 28.0 1.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 GAM20732.1 - 7.9e-05 22.4 0.1 0.00014 21.6 0.1 1.4 1 0 0 1 1 1 1 PH domain Lactonase PF10282.4 GAM20732.1 - 0.065 12.3 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.11 GAM20733.1 - 1.3e-37 129.2 48.0 6.4e-26 90.8 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM20733.1 - 2.2e-07 29.8 32.5 3.7e-06 25.7 22.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter PsbT PF01405.12 GAM20733.1 - 0.014 14.9 0.2 0.014 14.9 0.2 3.4 3 0 0 3 3 3 0 Photosystem II reaction centre T protein MFS_1 PF07690.11 GAM20734.1 - 1.1e-30 106.6 28.4 4.4e-25 88.1 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ten_N PF06484.7 GAM20734.1 - 1.2 8.2 5.1 1.2 8.1 1.7 2.0 2 0 0 2 2 2 0 Teneurin Intracellular Region WD40 PF00400.27 GAM20735.1 - 1.2e-13 50.3 8.2 4.8e-05 23.0 1.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat NHL PF01436.16 GAM20735.1 - 0.069 13.1 0.1 17 5.6 0.0 3.1 2 0 0 2 2 2 0 NHL repeat NUC153 PF08159.7 GAM20736.1 - 7.3e-08 31.8 2.2 1.8e-07 30.6 1.5 1.7 1 0 0 1 1 1 1 NUC153 domain DUF2951 PF11166.3 GAM20736.1 - 1.2 9.0 8.4 0.25 11.2 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Kri1_C PF12936.2 GAM20737.1 - 6e-24 83.8 2.8 6e-24 83.8 2.0 4.5 5 0 0 5 5 5 1 KRI1-like family C-terminal Pyr_redox_3 PF13738.1 GAM20737.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RabGAP-TBC PF00566.13 GAM20738.1 - 2.2e-26 92.6 0.3 3.5e-26 92.0 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-B_box PF00643.19 GAM20738.1 - 1.6e-05 24.6 4.5 1.6e-05 24.6 3.1 1.7 2 0 0 2 2 2 1 B-box zinc finger FYVE PF01363.16 GAM20738.1 - 0.0052 16.6 1.4 0.012 15.4 1.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 GAM20738.1 - 0.036 14.0 4.4 0.036 14.0 3.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM20738.1 - 0.091 12.5 4.0 0.25 11.0 2.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM20738.1 - 3.6 7.3 10.4 0.1 12.2 3.0 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM20738.1 - 3.8 7.4 11.2 0.058 13.2 2.8 1.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 GAM20738.1 - 9.9 6.1 14.1 0.033 14.0 2.9 2.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Daxx PF03344.10 GAM20739.1 - 0.61 8.4 35.4 0.012 14.1 19.6 1.7 2 0 0 2 2 2 0 Daxx Family DUF3439 PF11921.3 GAM20739.1 - 4.4 7.0 16.2 44 3.8 7.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Sigma70_ner PF04546.8 GAM20739.1 - 6.9 6.2 12.3 18 4.8 8.6 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region Crystall PF00030.14 GAM20740.1 - 0.0034 17.2 0.0 0.0096 15.7 0.0 1.9 1 1 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.5 GAM20740.1 - 0.015 15.0 0.0 0.048 13.3 0.0 2.0 1 1 0 1 1 1 0 Beta/Gamma crystallin L_protein_N PF15518.1 GAM20740.1 - 0.073 12.4 0.3 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 L protein N-terminus ABC_tran PF00005.22 GAM20741.1 - 2.4e-26 92.6 0.0 5.1e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAM20741.1 - 1.5e-25 89.9 30.3 3e-25 88.9 21.0 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM20741.1 - 5.4e-12 46.2 8.4 7.3e-08 32.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain ABC2_membrane PF01061.19 GAM20741.1 - 2.8e-05 23.4 25.1 2.8e-05 23.4 17.4 2.5 3 0 0 3 3 3 1 ABC-2 type transporter AAA_23 PF13476.1 GAM20741.1 - 5.3e-05 23.6 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAM20741.1 - 0.0011 18.2 0.3 0.96 8.6 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 GAM20741.1 - 0.01 15.2 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 GAM20741.1 - 0.014 14.8 0.3 0.041 13.4 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.10 GAM20741.1 - 0.017 13.8 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC2_membrane_4 PF12730.2 GAM20741.1 - 0.04 13.0 37.9 0.1 11.7 26.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein SbcCD_C PF13558.1 GAM20741.1 - 0.045 13.6 0.0 0.31 10.9 0.0 2.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 GAM20741.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 GAM20741.1 - 0.17 12.0 0.9 11 6.1 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM20741.1 - 0.21 11.3 0.1 0.43 10.3 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain ABC2_membrane_2 PF12679.2 GAM20741.1 - 0.22 10.3 14.1 0.15 10.9 7.6 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_30 PF13604.1 GAM20741.1 - 0.23 11.0 0.0 0.67 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF4449 PF14613.1 GAM20742.1 - 5.8e-05 23.0 1.1 5.8e-05 23.0 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.20 GAM20742.1 - 0.00041 19.7 0.2 0.0015 17.8 0.1 2.0 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Ank_2 PF12796.2 GAM20744.1 - 1.2e-18 67.2 3.1 2.7e-09 37.2 0.2 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20744.1 - 1.4e-13 50.5 3.4 0.00014 21.9 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM20744.1 - 3.8e-13 49.5 2.8 0.00045 20.6 0.6 5.3 1 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20744.1 - 6.4e-09 35.1 0.4 0.1 12.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 GAM20744.1 - 1e-08 34.5 3.7 0.00029 20.5 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Zip PF02535.17 GAM20744.1 - 0.0057 15.6 7.3 0.013 14.4 5.1 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter CTC1_2 PF15491.1 GAM20744.1 - 0.042 12.8 0.1 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Clp1 PF06807.9 GAM20745.1 - 5.4e-21 75.2 0.2 3.5e-20 72.6 0.1 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 GAM20745.1 - 1.5e-11 44.1 0.0 3.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAM20745.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAM20745.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Peptidase_C48 PF02902.14 GAM20746.1 - 2.8e-21 76.1 0.1 4e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Branch PF02485.16 GAM20747.1 - 1.5e-15 57.0 2.6 4.9e-15 55.3 1.8 1.9 1 1 0 1 1 1 1 Core-2/I-Branching enzyme DUF3139 PF11337.3 GAM20747.1 - 0.2 11.9 0.2 0.2 11.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) BTB PF00651.26 GAM20749.1 - 2.3e-16 59.7 0.0 6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 GAM20749.1 - 6.8e-06 25.8 0.1 6.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch MFS_1 PF07690.11 GAM20750.1 - 4.5e-34 117.7 18.4 7.5e-34 116.9 12.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NUDIX PF00293.23 GAM20751.1 - 1.4e-19 70.1 0.1 2.3e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Homez PF11569.3 GAM20751.1 - 0.12 11.4 1.2 3.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez zf-RING_UBOX PF13445.1 GAM20752.1 - 5.1e-07 29.3 3.8 5.1e-07 29.3 2.6 3.6 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 GAM20752.1 - 1.5e-06 28.1 7.8 1.5e-06 28.1 5.4 4.7 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM20752.1 - 5.3e-06 26.1 6.6 5.3e-06 26.1 4.6 3.7 3 0 0 3 3 3 2 Ring finger domain IBR PF01485.16 GAM20752.1 - 1.5e-05 24.7 9.7 1.5e-05 24.7 6.7 4.4 2 1 1 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 GAM20752.1 - 4.9e-05 22.8 4.5 4.9e-05 22.8 3.1 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM20752.1 - 0.0005 19.6 5.8 0.0005 19.6 4.0 3.9 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM20752.1 - 0.001 18.8 5.5 0.001 18.8 3.8 4.0 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAM20752.1 - 0.23 11.2 37.1 0.076 12.7 4.6 3.9 3 0 0 3 3 3 0 zinc-RING finger domain Metallophos PF00149.23 GAM20753.1 - 1.2e-35 122.7 0.9 1.7e-35 122.2 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 GAM20753.1 - 4.3e-26 90.7 3.7 4.7e-26 90.6 1.1 2.2 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 GAM20753.1 - 9.5e-18 63.6 4.8 2e-12 46.5 0.8 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM20753.1 - 5.1e-14 50.9 2.0 2.3e-07 30.1 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20753.1 - 6.2e-13 47.7 6.2 2.2e-07 30.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM20753.1 - 2e-08 34.1 1.0 5.7e-06 26.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20753.1 - 3.5e-08 33.3 0.0 6.6e-06 26.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20753.1 - 1.4e-07 31.9 0.6 0.00031 21.3 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20753.1 - 1.8e-07 30.3 1.7 0.00024 20.6 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20753.1 - 2.9e-07 30.7 0.2 2.6e-05 24.4 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20753.1 - 1.1e-05 25.3 1.8 0.0045 16.9 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20753.1 - 5.5e-05 22.6 0.1 0.012 15.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20753.1 - 0.0024 17.9 3.4 0.086 13.0 0.2 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM20753.1 - 0.91 9.7 6.9 1.1 9.3 3.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RRN7 PF11781.3 GAM20754.1 - 0.0022 17.4 3.1 0.0043 16.5 2.1 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-NADH-PPase PF09297.6 GAM20754.1 - 0.052 13.0 0.7 0.091 12.2 0.5 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain HD PF01966.17 GAM20759.1 - 5.5e-08 32.8 0.1 7.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 GAM20759.1 - 3.1e-05 23.3 0.6 7.9e-05 22.0 0.1 1.9 2 0 0 2 2 2 1 HDOD domain DUF706 PF05153.10 GAM20759.1 - 3.2e-05 23.4 0.1 4.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD_4 PF13328.1 GAM20759.1 - 8.6e-05 22.2 1.6 0.0002 21.0 1.1 1.7 1 1 0 1 1 1 1 HD domain GYF PF02213.11 GAM20759.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 GYF domain V-ATPase_H_C PF11698.3 GAM20759.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 V-ATPase subunit H PhyH PF05721.8 GAM20760.1 - 1.1e-32 113.8 0.0 1.3e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAM20760.1 - 0.0059 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 GAM20760.1 - 0.056 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Adeno_GP19K PF04881.8 GAM20760.1 - 0.09 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus GP19K DUF3592 PF12158.3 GAM20761.1 - 0.00022 21.0 1.6 0.00036 20.3 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3592) ATP_synt_I PF03899.10 GAM20761.1 - 0.74 10.0 9.7 2.6 8.2 1.5 2.2 2 0 0 2 2 2 0 ATP synthase I chain Ank_2 PF12796.2 GAM20762.1 - 9e-36 122.1 3.4 3.9e-13 49.5 0.0 3.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM20762.1 - 7e-22 76.0 1.0 0.00051 19.7 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAM20762.1 - 1e-19 70.4 1.9 2.4e-07 31.0 0.0 4.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20762.1 - 2.2e-19 69.0 1.6 6.4e-06 26.2 0.0 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20762.1 - 1.2e-14 52.8 0.1 0.49 10.7 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat PH PF00169.24 GAM20763.1 - 5e-08 33.0 1.8 5e-08 33.0 1.3 2.9 3 1 0 3 3 3 1 PH domain PH_11 PF15413.1 GAM20763.1 - 7.1e-05 23.0 0.3 0.00051 20.2 0.2 2.6 1 0 0 1 1 1 1 Pleckstrin homology domain Maelstrom PF13017.1 GAM20763.1 - 0.016 14.7 0.9 0.083 12.3 0.2 2.3 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Mago_nashi PF02792.9 GAM20766.1 - 2.8e-72 241.0 0.9 3.5e-72 240.7 0.6 1.1 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 GAM20766.1 - 0.00086 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) Tcf25 PF04910.9 GAM20767.1 - 9.1e-92 307.7 0.3 9.1e-92 307.7 0.2 1.9 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Fe_bilin_red PF05996.7 GAM20767.1 - 0.0026 17.2 0.5 0.0053 16.2 0.3 1.5 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase YL1 PF05764.8 GAM20767.1 - 0.52 9.8 22.5 1.2 8.7 15.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Ebola_NP PF05505.7 GAM20767.1 - 0.73 7.8 20.0 1.1 7.2 13.9 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein MtN3_slv PF03083.11 GAM20769.1 - 1e-27 95.8 14.7 7.7e-19 67.3 3.7 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF4191 PF13829.1 GAM20769.1 - 4 6.4 8.4 2.8 6.9 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Prefoldin PF02996.12 GAM20770.1 - 5.1e-26 90.6 1.7 5.1e-26 90.6 1.2 1.6 1 1 1 2 2 2 2 Prefoldin subunit PhoU_div PF01865.11 GAM20770.1 - 0.018 14.1 1.0 0.062 12.4 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF47 PRANC PF09372.5 GAM20770.1 - 0.037 13.9 0.9 0.083 12.8 0.6 1.6 1 0 0 1 1 1 0 PRANC domain SIMPL PF04402.9 GAM20770.1 - 0.077 12.8 1.6 0.84 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Epimerase PF01370.16 GAM20771.1 - 2.3e-14 53.3 0.0 3.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM20771.1 - 1.4e-07 30.6 0.0 1.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1731 PF08338.6 GAM20771.1 - 1.6e-05 24.2 0.0 3.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) NAD_binding_4 PF07993.7 GAM20771.1 - 7.7e-05 21.7 0.0 0.083 11.7 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM20771.1 - 0.0001 22.3 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 GAM20771.1 - 0.0013 17.5 0.0 0.0029 16.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 GAM20771.1 - 0.0016 18.3 0.0 0.079 12.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.18 GAM20771.1 - 0.012 15.4 0.2 0.022 14.5 0.0 1.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DDE_Tnp_4 PF13359.1 GAM20772.1 - 1.2e-22 80.2 0.5 2.5e-21 75.9 0.4 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM20772.1 - 6.4e-09 35.6 0.9 9.3e-09 35.1 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain zf-MYND PF01753.13 GAM20774.1 - 1.6e-06 27.8 13.8 2.8e-06 27.0 9.6 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 GAM20774.1 - 0.031 11.9 4.7 0.032 11.9 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Zn_ribbon_recom PF13408.1 GAM20774.1 - 0.13 12.5 3.2 0.28 11.4 2.2 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1212 PF06738.7 GAM20775.1 - 5.5e-42 143.4 8.9 2.3e-35 121.7 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAM20775.1 - 1.6e-17 63.6 31.5 2.7e-15 56.4 6.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) CASP_C PF08172.7 GAM20775.1 - 0.0076 15.3 1.2 0.013 14.5 0.9 1.3 1 0 0 1 1 1 1 CASP C terminal GNVR PF13807.1 GAM20775.1 - 0.38 10.5 4.2 14 5.5 1.2 3.4 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase IFRD PF05004.8 GAM20776.1 - 1.7e-12 47.0 13.8 5.8e-11 42.0 9.6 2.4 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) BUD22 PF09073.5 GAM20776.1 - 0.00044 19.4 23.1 0.00045 19.4 15.5 1.4 1 1 0 1 1 1 1 BUD22 DUF2076 PF09849.4 GAM20776.1 - 0.00063 19.8 8.1 0.001 19.1 5.6 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) SDA1 PF05285.7 GAM20776.1 - 0.0068 15.7 18.0 0.016 14.5 12.5 1.7 1 0 0 1 1 1 1 SDA1 Astro_capsid PF03115.9 GAM20776.1 - 0.0083 14.4 11.2 0.01 14.1 7.7 1.2 1 0 0 1 1 1 1 Astrovirus capsid protein precursor Baculo_LEF-11 PF06385.7 GAM20776.1 - 0.052 13.6 2.7 1.3 9.2 0.4 2.6 2 0 0 2 2 2 0 Baculovirus LEF-11 protein LIN37 PF15306.1 GAM20777.1 - 4.3e-06 26.7 10.8 4.3e-06 26.7 7.5 3.3 2 1 0 2 2 2 1 LIN37 PGAP1 PF07819.8 GAM20778.1 - 1.8e-08 34.2 0.0 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAM20778.1 - 4.6e-07 29.3 0.0 6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 GAM20778.1 - 4.2e-06 25.9 0.0 6.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 GAM20778.1 - 2.9e-05 24.0 0.0 4.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 GAM20778.1 - 3.2e-05 23.1 0.0 6.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 GAM20778.1 - 3.2e-05 23.7 0.0 5.1e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 GAM20778.1 - 0.00065 19.1 0.1 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 GAM20778.1 - 0.0012 18.3 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 GAM20778.1 - 0.014 14.7 0.1 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 2) Lipase_3 PF01764.20 GAM20778.1 - 0.055 13.0 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 GAM20778.1 - 0.091 12.3 0.1 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase RNA_pol_3_Rpc31 PF11705.3 GAM20779.1 - 7.1e-11 42.4 30.1 7.1e-11 42.4 20.8 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 GAM20779.1 - 1.9 8.1 22.6 0.023 14.4 9.3 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 GAM20779.1 - 2.8 7.4 15.3 0.042 13.3 5.9 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein TRAP_alpha PF03896.11 GAM20779.1 - 3.2 6.6 8.3 6.4 5.6 5.7 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1168 PF06658.7 GAM20779.1 - 3.2 7.2 14.3 0.3 10.6 6.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Metallophos PF00149.23 GAM20780.1 - 1e-16 60.9 1.2 2.5e-16 59.6 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM20780.1 - 5.2e-13 49.1 0.0 6.6e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 GAM20780.1 - 0.04 13.0 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Snf7 PF03357.16 GAM20782.1 - 1.6e-32 112.2 28.7 2e-32 111.9 19.9 1.1 1 0 0 1 1 1 1 Snf7 GidB PF02527.10 GAM20782.1 - 0.033 13.3 0.6 0.033 13.3 0.4 2.3 1 1 1 2 2 2 0 rRNA small subunit methyltransferase G ALMT PF11744.3 GAM20782.1 - 0.79 8.3 8.8 0.87 8.1 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DSPc PF00782.15 GAM20782.1 - 5.9 6.4 10.7 9.7 5.7 3.1 2.3 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Aldedh PF00171.17 GAM20784.1 - 3.5e-118 394.8 0.0 4.2e-118 394.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM20784.1 - 2.5e-07 29.7 0.0 4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DDE_Tnp_4 PF13359.1 GAM20785.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM20785.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain Metallophos PF00149.23 GAM20786.1 - 1.2e-10 41.1 1.7 3.3e-10 39.7 1.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM20786.1 - 0.00067 19.5 0.0 0.00099 18.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_11 PF13414.1 GAM20787.1 - 4.4e-16 58.2 8.8 7e-07 28.8 0.4 3.3 1 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 GAM20787.1 - 1.1e-15 56.5 18.4 3.1e-06 26.5 1.4 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM20787.1 - 1.8e-11 43.0 15.3 7.1e-05 22.4 1.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20787.1 - 8.7e-10 38.0 7.6 0.11 12.8 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20787.1 - 5.4e-09 35.1 11.2 0.0015 18.1 1.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20787.1 - 8.6e-09 35.2 6.2 0.00017 21.4 0.8 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM20787.1 - 2.1e-06 27.4 0.2 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20787.1 - 2.8e-05 24.3 0.3 0.32 11.7 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20787.1 - 7.9e-05 23.2 0.8 0.63 10.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20787.1 - 0.0063 16.8 0.7 2.4 8.5 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat RNA_pol_Rpb5_C PF01191.14 GAM20787.1 - 0.014 15.0 0.0 0.035 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain P4Ha_N PF08336.6 GAM20787.1 - 0.015 15.1 0.1 0.039 13.7 0.1 1.8 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CmcI PF04989.7 GAM20787.1 - 0.037 13.3 0.1 0.099 11.9 0.0 1.7 1 1 0 1 1 1 0 Cephalosporin hydroxylase TOM20_plant PF06552.7 GAM20787.1 - 0.044 13.3 0.1 0.14 11.6 0.1 1.8 1 1 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 CARDB PF07705.6 GAM20788.1 - 0.02 14.9 1.3 0.02 14.9 0.9 2.2 2 0 0 2 2 2 0 CARDB DUF2760 PF10816.3 GAM20788.1 - 0.089 12.2 0.1 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2760) DUF4369 PF14289.1 GAM20788.1 - 0.21 11.6 6.4 5.6 7.0 0.0 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4369) C2 PF00168.25 GAM20789.1 - 3e-14 52.6 0.1 6.9e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 GAM20789.1 - 1.7e-06 27.8 0.3 2.7e-05 23.9 0.2 2.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.6 GAM20789.1 - 0.00045 18.6 0.0 0.00093 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF810) SPT16 PF08644.6 GAM20789.1 - 0.1 12.4 2.6 0.42 10.4 0.2 2.9 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) DUF1777 PF08648.7 GAM20791.1 - 6.5e-05 22.7 22.2 7.4e-05 22.5 15.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Corona_nucleoca PF00937.13 GAM20791.1 - 0.00022 20.2 20.9 0.00033 19.7 14.5 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Transformer PF06495.6 GAM20791.1 - 0.00076 19.4 19.6 0.00099 19.0 13.6 1.3 1 0 0 1 1 1 1 Fruit fly transformer protein SR-25 PF10500.4 GAM20791.1 - 0.045 13.2 30.0 0.056 12.9 20.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.1 GAM20791.1 - 0.76 9.5 16.8 0.9 9.2 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) MIP-T3 PF10243.4 GAM20791.1 - 1.2 7.4 14.1 1.4 7.2 9.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AUX_IAA PF02309.11 GAM20791.1 - 1.3 8.6 7.2 1.5 8.5 5.0 1.1 1 0 0 1 1 1 0 AUX/IAA family Astro_capsid PF03115.9 GAM20791.1 - 1.7 6.7 13.1 2 6.5 9.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Apt1 PF10351.4 GAM20791.1 - 3.1 6.5 15.6 3.3 6.4 10.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.8 GAM20791.1 - 4.1 5.1 22.9 4.7 4.9 15.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FGF-BP1 PF06473.7 GAM20791.1 - 4.3 6.8 7.3 5.4 6.5 5.0 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Macoilin PF09726.4 GAM20791.1 - 4.7 5.3 16.0 4.5 5.4 11.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 GAM20791.1 - 5.9 5.8 13.7 6.5 5.6 9.5 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DDHD PF02862.12 GAM20791.1 - 6 6.5 10.1 7.1 6.3 7.0 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 GAM20791.1 - 6.6 4.6 12.7 7.5 4.4 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF566 PF04484.7 GAM20791.1 - 9.9 5.5 22.8 12 5.3 15.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) Sel1 PF08238.7 GAM20792.1 - 8.6e-54 178.7 52.4 2.9e-06 27.7 0.0 13.5 13 0 0 13 13 13 11 Sel1 repeat DUF1510 PF07423.6 GAM20792.1 - 0.0022 17.4 16.4 0.0022 17.4 11.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 GAM20792.1 - 0.12 10.0 14.4 0.19 9.3 10.0 1.2 1 0 0 1 1 1 0 Ycf1 Tetraspannin PF00335.15 GAM20792.1 - 0.3 10.3 1.5 0.6 9.3 1.0 1.5 1 0 0 1 1 1 0 Tetraspanin family Lig_chan PF00060.21 GAM20792.1 - 0.33 10.6 5.8 0.85 9.3 3.9 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel Neur_chan_memb PF02932.11 GAM20792.1 - 0.4 10.5 11.5 0.014 15.2 3.7 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Na_trans_assoc PF06512.8 GAM20792.1 - 0.83 9.5 11.8 2 8.3 8.2 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated OAD_gamma PF04277.8 GAM20792.1 - 2.1 8.8 4.8 1.3 9.4 0.1 2.8 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain PA26 PF04636.8 GAM20792.1 - 5.2 5.6 13.8 1.6 7.3 7.5 1.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Herpes_LP PF03363.8 GAM20793.1 - 0.42 10.1 10.0 0.79 9.2 3.1 2.3 1 1 1 2 2 2 0 Herpesvirus leader protein Nucleo_P87 PF07267.6 GAM20793.1 - 1.1 7.8 9.8 1.2 7.7 6.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ycf1 PF05758.7 GAM20793.1 - 1.3 6.6 6.2 1.3 6.6 4.3 1.1 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 GAM20793.1 - 1.6 8.0 20.2 2.1 7.6 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 GAM20793.1 - 2.9 5.5 9.0 3.3 5.3 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gastrin PF00918.12 GAM20793.1 - 3.8 8.3 6.5 2.8 8.7 3.0 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Mitofilin PF09731.4 GAM20793.1 - 4.3 5.8 20.5 5.2 5.6 14.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FancD2 PF14631.1 GAM20793.1 - 5.3 3.9 10.5 6.8 3.6 7.3 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease NARP1 PF12569.3 GAM20793.1 - 5.8 5.5 22.3 7.8 5.1 15.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hex_IIIa PF02455.11 GAM20793.1 - 6.4 5.3 8.9 7.6 5.0 6.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) U79_P34 PF03064.11 GAM20793.1 - 6.9 6.1 11.8 5.2 6.5 7.5 1.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 TFIID_30kDa PF03540.8 GAM20794.1 - 2.1e-26 91.5 0.0 3e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 GAM20794.1 - 0.033 13.8 1.0 0.18 11.5 0.1 2.5 2 1 0 2 2 2 0 Bromodomain associated Macoilin PF09726.4 GAM20794.1 - 0.39 8.9 12.9 0.4 8.8 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FNIP PF05725.7 GAM20795.1 - 1.7e-51 171.8 10.3 2.6e-11 43.2 0.0 7.8 6 1 0 8 8 8 6 FNIP Repeat FNIP PF05725.7 GAM20796.1 - 4e-21 74.6 25.3 4.9e-10 39.1 0.0 8.8 5 2 4 9 9 9 7 FNIP Repeat ETF_QO PF05187.8 GAM20797.1 - 1.3e-41 141.0 0.0 2.2e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 GAM20797.1 - 1.1e-09 37.6 0.1 6.7e-05 21.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM20797.1 - 2.7e-08 33.1 0.9 3.8e-05 22.7 1.4 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 GAM20797.1 - 1.3e-06 27.6 0.0 9e-06 24.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 GAM20797.1 - 6.9e-06 26.0 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM20797.1 - 5.1e-05 21.9 0.5 8.7e-05 21.1 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM20797.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM20797.1 - 0.00012 22.0 0.1 0.00025 21.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM20797.1 - 0.00013 21.7 0.1 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 GAM20797.1 - 0.00023 20.3 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM20797.1 - 0.00025 20.0 0.3 0.00042 19.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 GAM20797.1 - 0.00035 20.9 0.2 0.27 11.6 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 GAM20797.1 - 0.0014 18.9 0.6 0.0035 17.7 0.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.14 GAM20797.1 - 0.0036 16.4 0.2 0.006 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.1 GAM20797.1 - 0.0038 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 GAM20797.1 - 0.055 12.0 0.4 0.18 10.3 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 GAM20797.1 - 0.17 10.6 0.4 0.26 10.1 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MtN3_slv PF03083.11 GAM20799.1 - 1.3e-28 98.6 17.1 2e-16 59.5 0.7 3.1 4 0 0 4 4 4 2 Sugar efflux transporter for intercellular exchange HSCB_C PF07743.8 GAM20799.1 - 1e-13 51.5 1.2 1e-13 51.5 0.8 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 GAM20799.1 - 1.1e-07 31.4 0.3 1.1e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 GAM20799.1 - 0.054 13.3 1.3 0.068 12.9 0.3 1.6 2 0 0 2 2 2 0 Double zinc ribbon DUF1771 PF08590.5 GAM20800.1 - 5.5e-12 45.5 6.6 1e-11 44.6 4.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 GAM20800.1 - 5.3e-07 29.0 1.8 4.8e-05 22.7 0.1 2.6 2 0 0 2 2 2 2 CUE domain zf-CCCH PF00642.19 GAM20800.1 - 0.0025 17.4 0.9 0.0025 17.4 0.6 2.9 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 GAM20800.1 - 0.1 12.8 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Smr domain zf-C3H1 PF10650.4 GAM20800.1 - 1.9 8.0 7.7 3.3 7.2 0.5 2.6 2 0 0 2 2 2 0 Putative zinc-finger domain Pkinase PF00069.20 GAM20801.1 - 4.1e-65 219.5 0.0 8.7e-65 218.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20801.1 - 2.1e-45 154.8 0.0 3.3e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM20801.1 - 0.0052 16.5 0.1 0.019 14.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM20801.1 - 0.012 14.9 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 GAM20801.1 - 0.043 12.6 0.2 0.075 11.8 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ctr PF04145.10 GAM20802.1 - 2.4e-19 69.7 16.1 1.5e-17 63.9 11.1 2.1 1 1 0 1 1 1 1 Ctr copper transporter family ERGIC_N PF13850.1 GAM20802.1 - 0.015 15.2 1.1 0.023 14.6 0.2 1.7 1 1 1 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2798 PF11391.3 GAM20802.1 - 0.038 13.7 1.1 0.038 13.7 0.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) DUF3307 PF11750.3 GAM20802.1 - 0.42 10.3 2.9 4.8 6.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3307) DUF2768 PF10966.3 GAM20802.1 - 0.78 9.9 6.4 1.9 8.6 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2768) COX6C PF02937.10 GAM20802.1 - 4 7.3 5.2 4.5 7.2 0.1 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIc Cyclin PF08613.6 GAM20803.1 - 1.2e-30 106.8 0.4 1.2e-30 106.8 0.3 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM20803.1 - 7.9e-11 41.6 0.1 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Porin_3 PF01459.17 GAM20804.1 - 2.3e-33 115.6 0.4 3.4e-33 115.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic porin Hom_end_hint PF05203.11 GAM20804.1 - 0.036 13.7 0.3 0.034 13.8 0.2 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Glyco_transf_15 PF01793.11 GAM20804.1 - 0.21 10.5 6.6 0.28 10.0 4.6 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4628 PF15429.1 GAM20804.1 - 0.35 10.2 7.9 0.51 9.7 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Med15 PF09606.5 GAM20804.1 - 0.87 7.7 29.4 1 7.4 20.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 GAM20804.1 - 2.8 7.7 5.8 3.7 7.3 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U57 PF05582.7 GAM20804.1 - 2.8 6.8 7.7 3.6 6.4 5.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Glyco_hydro_15 PF00723.16 GAM20805.1 - 8.2e-17 60.8 0.0 1.9e-16 59.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 15 zf-HIT PF04438.11 GAM20806.1 - 1.7e-06 27.5 7.9 2.9e-06 26.7 5.5 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 GAM20806.1 - 1.7 8.6 8.5 3.5 7.5 5.9 1.6 1 0 0 1 1 1 0 B-box zinc finger DUF3745 PF12560.3 GAM20807.1 - 0.1 12.2 0.5 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3745) L27 PF02828.11 GAM20807.1 - 1.2 8.9 6.6 0.47 10.1 1.4 2.7 3 0 0 3 3 3 0 L27 domain DUF1338 PF07063.8 GAM20808.1 - 0.023 13.7 0.4 0.025 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Mu-like_Pro PF10123.4 GAM20808.1 - 0.046 13.1 2.8 0.05 13.0 2.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Plexin_cytopl PF08337.7 GAM20808.1 - 0.12 10.7 2.5 0.12 10.6 1.7 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain FAD-oxidase_C PF02913.14 GAM20808.1 - 0.12 11.7 0.1 0.18 11.0 0.1 1.4 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain bZIP_2 PF07716.10 GAM20808.1 - 0.17 11.7 2.6 9.7 6.1 0.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 GAM20808.1 - 0.25 11.3 4.1 4 7.4 0.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Striatin PF08232.7 GAM20808.1 - 0.33 11.2 6.7 1.2 9.4 4.6 1.7 1 1 0 1 1 1 0 Striatin family TMF_DNA_bd PF12329.3 GAM20808.1 - 0.5 10.2 7.6 2 8.2 1.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding AATF-Che1 PF13339.1 GAM20808.1 - 0.59 10.2 5.8 0.89 9.7 3.8 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor APC_CDC26 PF10471.4 GAM20808.1 - 1.1 10.0 5.5 9 7.1 1.3 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 DivIVA PF05103.8 GAM20808.1 - 1.4 9.0 7.3 0.56 10.2 1.1 2.1 1 1 1 2 2 2 0 DivIVA protein DUF972 PF06156.8 GAM20808.1 - 3.3 8.1 6.9 2.2 8.6 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 GAM20808.1 - 7 7.0 8.7 26 5.2 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) zf-NF-X1 PF01422.12 GAM20809.1 - 1.8e-08 34.1 256.8 0.00014 21.7 11.0 17.1 17 0 0 17 17 17 10 NF-X1 type zinc finger DUF3948 PF13134.1 GAM20809.1 - 0.68 9.4 2.0 1.2 8.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) CLU PF13236.1 GAM20810.1 - 6.7e-60 202.2 0.0 1.5e-59 201.0 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria VHP PF02209.14 GAM20810.1 - 1.2e-09 37.6 1.8 4.5e-09 35.8 1.3 2.1 1 0 0 1 1 1 1 Villin headpiece domain LRR_6 PF13516.1 GAM20810.1 - 1.5e-07 30.7 40.3 3.1 8.1 0.0 14.8 16 1 1 17 17 17 1 Leucine Rich repeat LRR_4 PF12799.2 GAM20810.1 - 5.8e-07 28.9 38.3 0.041 13.5 0.8 9.6 5 2 5 10 10 10 5 Leucine Rich repeats (2 copies) eIF3_p135 PF12807.2 GAM20810.1 - 1.3e-06 28.4 1.7 2.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.1 GAM20810.1 - 2.2e-05 24.0 4.8 0.00037 20.0 0.7 3.4 3 0 0 3 3 3 1 TPR repeat LRR_8 PF13855.1 GAM20810.1 - 4.6e-05 23.0 42.6 0.017 14.8 0.2 8.1 1 1 6 10 10 10 5 Leucine rich repeat TPR_17 PF13431.1 GAM20810.1 - 0.00011 22.1 0.1 0.031 14.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat LRR_1 PF00560.28 GAM20810.1 - 0.00019 21.0 37.7 8.7 6.8 0.0 13.3 13 1 1 14 14 14 1 Leucine Rich Repeat TOM20_plant PF06552.7 GAM20810.1 - 0.0003 20.4 0.4 0.012 15.2 0.0 3.0 1 1 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.1 GAM20810.1 - 0.014 15.6 0.2 0.16 12.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_7 PF13504.1 GAM20810.1 - 0.032 14.3 33.9 23 5.8 0.0 12.8 13 2 0 13 13 12 0 Leucine rich repeat YL1 PF05764.8 GAM20810.1 - 0.98 8.9 14.7 2.6 7.6 10.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein CIAPIN1 PF05093.8 GAM20811.1 - 8.4e-26 89.9 7.0 1.9e-25 88.8 4.8 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Peripla_BP_4 PF13407.1 GAM20811.1 - 0.051 12.9 0.8 0.084 12.2 0.5 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain ELO PF01151.13 GAM20812.1 - 4e-63 213.0 23.5 4.5e-63 212.8 16.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.3 GAM20812.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3290) MRP-S35 PF10246.4 GAM20813.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 FNIP PF05725.7 GAM20814.1 - 1.3e-83 274.7 30.4 1.2e-12 47.5 0.1 9.6 7 1 2 10 10 10 8 FNIP Repeat DUF845 PF05820.6 GAM20814.1 - 0.02 14.6 0.0 7.8 6.2 0.0 3.5 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF845) PMM PF03332.8 GAM20816.1 - 7.7e-102 339.5 0.3 8.8e-102 339.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 GAM20816.1 - 8.3e-05 22.2 0.0 0.00028 20.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 GAM20816.1 - 0.01 15.1 0.0 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 GAM20816.1 - 0.027 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 GAM20816.1 - 0.052 12.6 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein MFS_1 PF07690.11 GAM20817.1 - 1e-56 192.1 22.6 8.9e-39 133.1 1.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM20817.1 - 4.5e-13 48.5 16.2 1.8e-12 46.6 1.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAM20817.1 - 1.1e-11 43.7 23.0 1.1e-07 30.6 3.8 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 GAM20817.1 - 0.0013 16.9 10.6 0.015 13.4 2.8 2.6 2 0 0 2 2 2 2 Transmembrane secretion effector BT1 PF03092.11 GAM20817.1 - 0.0043 15.8 4.9 0.22 10.1 0.1 2.9 2 1 0 3 3 3 2 BT1 family LacY_symp PF01306.14 GAM20817.1 - 0.023 13.2 25.0 0.0052 15.4 3.7 2.7 2 1 0 2 2 2 0 LacY proton/sugar symporter DUF2688 PF10892.3 GAM20818.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) POR PF01558.13 GAM20819.1 - 2 8.2 7.8 4.9 7.0 1.9 2.1 1 1 1 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PTPA PF03095.10 GAM20821.1 - 1.4e-109 365.9 0.1 1.6e-109 365.6 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TAP42 PF04177.7 GAM20822.1 - 4.2e-57 193.6 12.8 6.3e-34 117.4 4.8 2.7 1 1 1 2 2 2 2 TAP42-like family FNIP PF05725.7 GAM20823.1 - 6.9e-09 35.5 3.2 0.0034 17.3 0.0 4.4 4 2 0 4 4 4 3 FNIP Repeat zf-RNPHF PF08080.7 GAM20823.1 - 0.014 14.8 0.7 3.6 7.1 0.1 2.8 2 0 0 2 2 2 0 RNPHF zinc finger DUF1049 PF06305.6 GAM20824.1 - 0.096 12.1 0.6 0.18 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Vpu PF00558.14 GAM20824.1 - 0.18 11.3 0.2 0.33 10.5 0.2 1.5 1 0 0 1 1 1 0 Vpu protein DUF605 PF04652.11 GAM20825.1 - 0.014 14.8 30.7 0.02 14.3 21.3 1.3 1 0 0 1 1 1 0 Vta1 like HC2 PF07382.6 GAM20825.1 - 0.5 10.2 31.2 0.72 9.6 21.7 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 TFIIA PF03153.8 GAM20825.1 - 0.64 9.8 22.8 0.88 9.3 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AvrE PF11725.3 GAM20825.1 - 1.6 5.6 17.8 1.8 5.4 12.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Macoilin PF09726.4 GAM20825.1 - 6.9 4.8 27.9 9.1 4.4 19.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DDE_Tnp_4 PF13359.1 GAM20826.1 - 3.1e-27 95.1 0.0 4.1e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM20826.1 - 5.4e-11 42.4 0.3 1.4e-10 41.0 0.2 1.6 1 1 0 1 1 1 1 Transposase DDE domain Peptidase_C1 PF00112.18 GAM20827.1 - 2.9e-76 256.2 9.0 3.8e-76 255.7 6.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM20827.1 - 3.4e-14 52.8 5.3 6.5e-14 51.9 3.7 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM20827.1 - 0.00013 20.6 0.9 0.0098 14.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family DUF1514 PF07438.6 GAM20827.1 - 0.36 10.7 1.4 0.83 9.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) RasGEF PF00617.14 GAM20828.1 - 1.3e-58 197.8 0.5 1.3e-58 197.8 0.3 2.1 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAM20828.1 - 2.5e-24 85.3 0.7 2.5e-24 85.3 0.5 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif Acetyltransf_11 PF13720.1 GAM20828.1 - 0.039 14.1 0.1 4.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SHMT PF00464.14 GAM20829.1 - 2.5e-190 632.0 0.0 2.9e-190 631.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 GAM20829.1 - 0.0027 16.9 0.0 0.008 15.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 GAM20829.1 - 0.0041 15.8 0.0 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Helicase_C_4 PF13871.1 GAM20829.1 - 0.15 11.4 0.0 1.7 7.9 0.0 2.1 1 1 0 1 1 1 0 Helicase_C-like FNIP PF05725.7 GAM20830.1 - 4.8e-43 144.8 17.2 3.9e-10 39.5 0.0 7.9 5 1 3 9 9 9 8 FNIP Repeat EGF_2 PF07974.8 GAM20831.1 - 0.0082 16.2 14.2 0.014 15.5 9.8 1.4 1 0 0 1 1 1 1 EGF-like domain Flavi_NS2B PF01002.14 GAM20831.1 - 0.08 12.5 0.1 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B Vpu PF00558.14 GAM20831.1 - 0.29 10.6 0.7 0.58 9.7 0.5 1.5 1 0 0 1 1 1 0 Vpu protein FNIP PF05725.7 GAM20833.1 - 2.1e-56 187.6 31.8 4.2e-12 45.8 0.2 9.6 5 3 4 10 10 10 9 FNIP Repeat LRR_7 PF13504.1 GAM20833.1 - 2.6 8.6 11.2 13 6.5 0.1 6.6 7 0 0 7 7 7 0 Leucine rich repeat ABC2_membrane_3 PF12698.2 GAM20834.1 - 7e-26 91.0 31.2 1e-25 90.5 21.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 GAM20834.1 - 1.8e-24 86.6 0.0 3.2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM20834.1 - 8.9e-13 48.8 0.5 7.1e-09 36.0 0.0 3.1 2 1 0 3 3 3 2 AAA domain ABC2_membrane PF01061.19 GAM20834.1 - 0.00016 20.9 24.2 0.00016 20.9 16.8 3.1 2 1 1 3 3 3 2 ABC-2 type transporter AAA_23 PF13476.1 GAM20834.1 - 0.0003 21.1 0.1 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAM20834.1 - 0.0009 18.3 0.0 0.053 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 GAM20834.1 - 0.006 16.0 0.2 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma70_ner PF04546.8 GAM20834.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1900 PF08954.6 GAM20835.1 - 1.8e-58 195.9 0.0 7.9e-58 193.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 GAM20835.1 - 8.9e-34 114.9 0.4 1.9e-33 113.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 GAM20835.1 - 9.2e-24 82.4 0.6 6.3e-07 29.0 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat CLU PF13236.1 GAM20836.1 - 1.7e-59 200.9 0.0 3e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM20836.1 - 1.5e-10 41.2 2.0 3.1e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.1 GAM20836.1 - 2.1e-08 33.3 29.8 0.34 11.1 0.0 11.5 13 0 0 13 13 13 4 Leucine Rich repeat LRR_4 PF12799.2 GAM20836.1 - 4.4e-07 29.3 23.0 0.055 13.0 0.0 8.5 6 3 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM20836.1 - 0.00052 19.6 30.5 14 6.1 0.0 11.2 12 2 0 12 12 12 1 Leucine Rich Repeat LRR_7 PF13504.1 GAM20836.1 - 0.078 13.2 13.6 6.5 7.4 0.0 8.2 9 0 0 9 9 9 0 Leucine rich repeat ATP-synt_G PF04718.10 GAM20838.1 - 5.8e-07 30.1 0.1 7.3e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Ras PF00071.17 GAM20839.1 - 1.9e-57 193.1 0.0 2.2e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM20839.1 - 6.2e-16 58.9 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM20839.1 - 4.8e-09 35.6 0.0 6.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM20839.1 - 0.00016 21.1 0.0 0.00083 18.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM20839.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM20839.1 - 0.07 13.0 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pro-kuma_activ PF09286.6 GAM20840.1 - 1.4e-29 103.0 0.1 1.6e-29 102.7 0.1 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain P5-ATPase PF12409.3 GAM20842.1 - 0.0055 16.5 3.5 0.0076 16.0 2.1 1.3 1 1 0 1 1 1 1 P5-type ATPase cation transporter ArfGap PF01412.13 GAM20843.1 - 2.5e-39 133.6 0.6 8.1e-39 132.0 0.4 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 GAM20843.1 - 1.3e-12 47.8 1.6 2.3e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.2 GAM20843.1 - 2.3e-11 43.8 0.0 7.3e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20843.1 - 1e-09 38.6 0.1 1e-08 35.4 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20843.1 - 1.2e-09 38.0 0.3 1.7e-08 34.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) BAR PF03114.13 GAM20843.1 - 1.2e-08 34.8 6.3 2e-08 34.0 4.3 1.4 1 0 0 1 1 1 1 BAR domain Ank PF00023.25 GAM20843.1 - 1.3e-08 34.1 0.1 0.00046 19.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.1 GAM20843.1 - 0.00034 20.8 4.3 0.00035 20.7 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain Ank_3 PF13606.1 GAM20843.1 - 0.00035 20.5 0.0 0.088 13.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat PH_4 PF15404.1 GAM20843.1 - 0.001 18.6 0.7 0.063 12.8 0.0 3.2 1 1 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 GAM20843.1 - 0.0046 17.1 0.1 0.0046 17.1 0.0 2.5 3 0 0 3 3 3 1 Pleckstrin homology domain RNase_H PF00075.19 GAM20844.1 - 4.8e-29 101.3 0.0 5.6e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 RNase H RNase_H PF00075.19 GAM20845.1 - 3.6e-34 117.9 0.1 4.3e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 GAM20845.1 - 0.0048 16.6 0.0 0.013 15.3 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase-like Clathrin_bdg PF15045.1 GAM20845.1 - 0.093 12.2 0.3 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking ELMO_CED12 PF04727.8 GAM20846.1 - 1.3e-35 122.4 1.8 2.9e-35 121.3 0.4 2.1 2 0 0 2 2 2 1 ELMO/CED-12 family 7tm_2 PF00002.19 GAM20848.1 - 5.1e-13 48.6 10.9 6e-13 48.4 7.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 GAM20848.1 - 6.1e-13 48.5 13.1 8.8e-13 47.9 9.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 GAM20848.1 - 8.5e-12 44.5 13.3 2.8e-10 39.5 6.4 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Frizzled PF01534.12 GAM20848.1 - 0.0053 15.5 10.5 0.0074 15.1 7.3 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Git3_C PF11970.3 GAM20848.1 - 0.0066 16.1 0.3 0.0066 16.1 0.2 2.8 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Ocular_alb PF02101.10 GAM20848.1 - 0.09 11.3 9.8 0.17 10.4 5.4 2.3 2 1 1 3 3 3 0 Ocular albinism type 1 protein FixQ PF05545.6 GAM20848.1 - 1.7 8.3 12.1 0.67 9.6 1.0 3.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Med28 PF11594.3 GAM20849.1 - 0.00047 20.3 0.1 0.00052 20.2 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 28 DivIC PF04977.10 GAM20849.1 - 0.04 13.4 0.8 0.052 13.0 0.5 1.2 1 0 0 1 1 1 0 Septum formation initiator Med9 PF07544.8 GAM20849.1 - 0.04 13.6 1.4 0.071 12.8 1.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4315 PF14193.1 GAM20849.1 - 0.21 11.5 2.4 0.76 9.7 1.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) Ank PF00023.25 GAM20850.1 - 8.7e-70 227.2 10.8 8e-08 31.7 0.1 9.6 9 0 0 9 9 9 9 Ankyrin repeat Ank_2 PF12796.2 GAM20850.1 - 5.3e-67 222.1 5.9 5.8e-17 61.8 0.1 5.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) RabGAP-TBC PF00566.13 GAM20850.1 - 8e-58 195.4 3.5 8e-58 195.4 2.4 2.4 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Ank_4 PF13637.1 GAM20850.1 - 4.9e-50 167.0 11.4 1.1e-11 44.8 0.0 8.2 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20850.1 - 1.5e-47 158.5 11.6 2.9e-08 33.6 0.2 6.7 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20850.1 - 3.6e-38 125.7 8.5 0.00056 19.9 0.1 9.4 9 0 0 9 9 9 8 Ankyrin repeat Patatin PF01734.17 GAM20851.1 - 1.5e-16 60.9 1.3 3.8e-15 56.3 0.9 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4347 PF14252.1 GAM20851.1 - 0.0021 17.5 1.0 0.0049 16.3 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) DUF1524 PF07510.6 GAM20851.1 - 0.013 15.3 2.4 0.021 14.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) Rad10 PF03834.9 GAM20851.1 - 0.48 10.1 4.6 0.47 10.1 0.4 2.7 3 0 0 3 3 3 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Yippee-Mis18 PF03226.9 GAM20852.1 - 8.7e-20 70.5 0.7 9.9e-20 70.3 0.5 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 GAM20852.1 - 0.0029 17.4 2.4 0.0051 16.6 1.6 1.4 1 1 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.4 GAM20852.1 - 0.029 14.3 0.5 0.083 12.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Tnp_zf-ribbon_2 PF13842.1 GAM20852.1 - 0.092 13.1 1.3 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon LIM PF00412.17 GAM20852.1 - 0.13 12.3 1.1 13 5.9 0.1 2.3 2 0 0 2 2 2 0 LIM domain zf-DNL PF05180.7 GAM20852.1 - 0.44 10.2 2.4 0.5 10.1 0.0 2.1 2 1 0 2 2 2 0 DNL zinc finger DUF177 PF02620.12 GAM20853.1 - 0.17 11.9 2.6 21 5.1 1.6 2.5 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 Nop14 PF04147.7 GAM20853.1 - 0.93 7.3 5.9 1.4 6.7 4.1 1.2 1 0 0 1 1 1 0 Nop14-like family EF-hand_6 PF13405.1 GAM20854.1 - 3.7e-08 32.5 4.8 0.022 14.6 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 GAM20854.1 - 1.1e-07 31.8 3.3 0.00086 19.3 0.9 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM20854.1 - 3.4e-06 26.5 4.2 0.0027 17.3 0.2 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM20854.1 - 7.1e-06 24.9 8.8 0.0036 16.5 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 GAM20854.1 - 7e-05 22.6 0.2 0.25 11.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain UBA PF00627.26 GAM20854.1 - 0.00014 21.5 0.0 0.0004 20.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF2197 PF09963.4 GAM20854.1 - 0.15 12.0 3.3 2.2 8.2 0.7 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-TFIIIC PF12660.2 GAM20854.1 - 1.6 8.7 10.7 5.5 6.9 7.4 2.0 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex DNA_RNApol_7kD PF03604.8 GAM20854.1 - 1.7 8.2 9.1 5.1 6.6 0.8 2.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit GBP PF02263.14 GAM20855.1 - 0.00018 20.6 0.1 0.00035 19.7 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 GAM20855.1 - 0.00075 19.4 0.2 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1829 PF08862.5 GAM20855.1 - 0.065 13.5 0.3 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF1829 Kelch_6 PF13964.1 GAM20856.1 - 1.6e-10 40.6 5.5 3.1e-06 27.1 0.1 4.5 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM20856.1 - 4e-06 26.5 6.2 0.013 15.2 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM20856.1 - 5.3e-05 22.8 0.1 1.1 9.1 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM20856.1 - 0.00065 19.8 0.6 2.1 8.6 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Ribophorin_II PF05817.9 GAM20856.1 - 0.0055 14.9 0.2 0.0064 14.7 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Kelch_1 PF01344.20 GAM20856.1 - 0.067 12.7 0.0 0.067 12.7 0.0 5.0 6 0 0 6 6 6 0 Kelch motif Ank_2 PF12796.2 GAM20858.1 - 0.004 17.4 0.5 0.89 9.9 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Peptidase_C48 PF02902.14 GAM20860.1 - 8.6e-36 123.5 1.7 3.7e-35 121.5 1.2 2.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAM91_C PF14648.1 GAM20861.1 - 4.9e-118 394.8 0.0 3.5e-97 326.0 0.0 2.1 1 1 1 2 2 2 2 FAM91 C-terminus FAM91_N PF14647.1 GAM20861.1 - 1.1e-112 376.1 0.5 1.5e-112 375.6 0.4 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Pkinase PF00069.20 GAM20862.1 - 7.6e-49 166.1 0.0 1.4e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20862.1 - 2e-46 158.1 0.0 3e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 GAM20862.1 - 2.4e-26 91.8 2.2 1.7e-09 37.9 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM20862.1 - 1.5e-22 78.2 0.3 7.8e-05 22.2 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat C2 PF00168.25 GAM20862.1 - 3.2e-21 74.9 0.0 1.3e-20 73.0 0.0 2.1 2 0 0 2 2 2 1 C2 domain Ank_4 PF13637.1 GAM20862.1 - 4.1e-21 74.9 2.4 6.2e-06 26.5 0.0 5.0 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20862.1 - 6.2e-19 67.6 0.1 3.8e-06 26.9 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20862.1 - 4.7e-16 57.2 3.2 4.7e-05 23.2 0.0 5.4 6 0 0 6 6 6 3 Ankyrin repeat SAM_2 PF07647.12 GAM20862.1 - 1.6e-06 27.8 0.0 4.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM20862.1 - 4.2e-05 23.6 0.2 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) APH PF01636.18 GAM20862.1 - 0.0067 16.1 0.1 0.026 14.2 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM20862.1 - 0.065 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FokI_N PF02981.10 GAM20862.1 - 0.14 11.7 0.4 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain RAP1 PF07218.6 GAM20862.1 - 0.6 8.1 9.2 0.89 7.5 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S14 PF00253.16 GAM20863.1 - 5.1e-16 57.7 3.7 5.6e-16 57.6 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1451 PF07295.6 GAM20863.1 - 0.092 12.5 0.5 0.11 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) zf-FPG_IleRS PF06827.9 GAM20863.1 - 8.9 6.0 8.8 54 3.5 6.1 2.0 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Pkinase PF00069.20 GAM20864.1 - 8e-65 218.5 0.0 9.8e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20864.1 - 3.5e-26 91.8 0.1 9.4e-26 90.4 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM20864.1 - 2.3e-07 30.0 0.0 3.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 GAM20864.1 - 0.00025 20.6 0.2 0.00044 19.8 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 GAM20864.1 - 0.0046 16.7 0.0 0.021 14.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Chor_lyase PF04345.8 GAM20864.1 - 0.053 12.9 0.1 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Chorismate lyase MVL PF12151.3 GAM20865.1 - 0.094 12.3 0.3 0.094 12.3 0.2 2.3 1 1 1 2 2 2 0 Mannan-binding protein Defensin_2 PF01097.13 GAM20865.1 - 5.5 6.7 11.7 0.25 11.1 0.7 3.0 3 0 0 3 3 3 0 Arthropod defensin E1-E2_ATPase PF00122.15 GAM20866.1 - 4.4e-22 78.2 0.0 4.4e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM20866.1 - 1.8e-16 61.2 0.0 1e-15 58.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM20866.1 - 5.3e-11 43.0 0.0 2e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM20866.1 - 7e-10 38.7 0.0 2.4e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM20866.1 - 0.00025 20.6 1.2 0.00098 18.7 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 GAM20867.1 - 1.7e-14 53.1 0.0 3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20867.1 - 4e-14 52.3 0.0 6.5e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20867.1 - 1.4e-08 34.4 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M16 PF00675.15 GAM20868.1 - 3.2e-31 108.1 0.0 7.9e-31 106.8 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAM20868.1 - 1.4e-21 77.0 0.0 5.5e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain UCH PF00443.24 GAM20869.1 - 5.3e-24 84.7 10.0 2e-23 82.8 6.9 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBM_20 PF00686.14 GAM20869.1 - 3.1e-15 55.5 2.8 1.5e-07 30.8 0.1 3.5 3 0 0 3 3 3 3 Starch binding domain DUF3732 PF12532.3 GAM20869.1 - 0.0028 17.1 2.1 0.028 13.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3732) His_binding PF02098.11 GAM20869.1 - 0.035 13.9 0.8 0.096 12.4 0.5 1.7 1 0 0 1 1 1 0 Tick histamine binding protein HAP2-GCS1 PF10699.4 GAM20870.1 - 0.00083 19.2 0.1 0.003 17.4 0.0 2.0 2 0 0 2 2 2 1 Male gamete fusion factor Ank_2 PF12796.2 GAM20871.1 - 4.1e-14 52.6 2.5 0.0043 17.3 0.0 7.8 8 2 0 8 8 8 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20871.1 - 0.0087 16.5 6.3 59 4.3 0.3 7.0 7 1 1 8 8 8 0 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM20871.1 - 0.13 12.1 14.9 0.6 9.9 0.1 6.1 6 0 0 6 6 6 0 Domain of unknown function (DUF3447) TAF8_C PF10406.4 GAM20872.1 - 2.7e-17 62.5 0.7 7.7e-17 61.0 0.5 1.8 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 GAM20872.1 - 2.7e-16 59.0 0.1 4.8e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF1212 PF06738.7 GAM20873.1 - 1.7 8.0 6.8 4.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Trm112p PF03966.11 GAM20874.1 - 1.2e-10 41.6 0.1 1.7e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.1 GAM20874.1 - 0.02 14.5 0.1 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAM20874.1 - 0.028 13.9 0.1 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Vps52 PF04129.7 GAM20874.1 - 0.051 12.0 0.3 0.066 11.7 0.2 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family GST_C PF00043.20 GAM20875.1 - 3e-14 52.7 0.1 5.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM20875.1 - 5e-10 39.1 0.3 1.5e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM20875.1 - 8.9e-10 38.6 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM20875.1 - 6e-09 35.7 0.0 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM20875.1 - 2.4e-08 34.0 0.0 5.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM20875.1 - 4e-07 30.4 0.1 6.3e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M66 PF10462.4 GAM20876.1 - 6e-43 146.8 0.0 1e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M66 ELFV_dehydrog PF00208.16 GAM20879.1 - 1.8e-46 158.6 0.0 2.8e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 GAM20879.1 - 3.8e-24 84.3 0.3 8.7e-16 56.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 GAM20879.1 - 0.041 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pro-kuma_activ PF09286.6 GAM20880.1 - 1.2e-33 116.1 0.3 2.5e-33 115.1 0.2 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM20880.1 - 2.8e-07 29.9 3.4 6e-07 28.8 2.4 1.5 1 0 0 1 1 1 1 Subtilase family RRM_1 PF00076.17 GAM20881.1 - 1.2e-14 53.6 0.0 1.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20881.1 - 1.2e-08 34.7 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20881.1 - 5.9e-08 32.4 0.0 9.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 GAM20881.1 - 7.2e-08 31.9 13.4 2.9e-06 26.9 2.0 2.8 3 0 0 3 3 3 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 GAM20881.1 - 0.024 14.6 4.3 0.12 12.3 3.1 1.9 1 1 0 1 1 1 0 DnaJ central domain DUF2318 PF10080.4 GAM20881.1 - 0.066 12.9 1.6 0.1 12.3 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-CCHC_3 PF13917.1 GAM20881.1 - 9 6.1 9.3 15 5.4 0.5 2.5 1 1 1 2 2 2 0 Zinc knuckle PG_binding_1 PF01471.13 GAM20882.1 - 7.5e-07 29.0 0.0 7.1e-06 25.9 0.0 2.7 3 0 0 3 3 3 1 Putative peptidoglycan binding domain CRA PF06589.6 GAM20882.1 - 0.0055 16.0 1.3 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Circumsporozoite-related antigen (CRA) CorA PF01544.13 GAM20882.1 - 5.4 5.9 18.3 0.07 12.1 5.8 2.6 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein PHR PF08005.7 GAM20883.1 - 6.1e-27 94.6 1.6 4e-26 92.0 1.1 2.4 2 0 0 2 2 2 1 PHR domain zf-RING_2 PF13639.1 GAM20883.1 - 2.4e-07 30.4 8.3 2.4e-07 30.4 5.7 4.8 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM20883.1 - 0.00025 21.0 8.3 0.00025 21.0 5.7 5.1 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM20883.1 - 0.0019 17.9 6.0 0.0019 17.9 4.1 4.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-B_box PF00643.19 GAM20883.1 - 0.0019 18.0 4.9 0.0019 18.0 3.4 4.2 3 1 0 3 3 3 1 B-box zinc finger Gag_spuma PF03276.9 GAM20883.1 - 2.7 6.2 1.4 6 5.0 1.0 1.5 1 0 0 1 1 1 0 Spumavirus gag protein FNIP PF05725.7 GAM20884.1 - 2.2e-72 238.7 0.1 3.8e-14 52.3 0.0 9.0 6 2 3 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 GAM20884.1 - 0.0014 18.5 8.8 3.8 7.5 0.1 6.1 4 1 1 6 6 6 2 Protein of unknown function (DUF1769) PH PF00169.24 GAM20885.1 - 3.2e-12 46.5 0.1 9.9e-12 44.9 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM20885.1 - 2.1e-05 24.7 1.4 2.1e-05 24.7 1.0 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM20885.1 - 5.3e-05 23.2 0.6 0.00019 21.4 0.4 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 GAM20885.1 - 0.0028 17.5 2.3 0.021 14.7 0.2 3.0 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology WD40 PF00400.27 GAM20885.1 - 0.0043 16.8 0.0 0.02 14.7 0.0 2.2 1 0 0 1 1 1 1 WD domain, G-beta repeat adh_short PF00106.20 GAM20886.1 - 5.5e-15 55.6 0.3 1e-14 54.7 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM20886.1 - 3e-06 26.8 0.1 3.8e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 GAM20886.1 - 7e-06 25.8 0.3 1.1e-05 25.2 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM20886.1 - 0.001 18.2 0.0 0.0035 16.5 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM20886.1 - 0.0015 18.5 0.5 0.12 12.3 0.0 2.6 2 1 1 3 3 3 1 NADH(P)-binding adh_short_C2 PF13561.1 GAM20886.1 - 0.0029 17.4 0.0 0.0051 16.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase IncA PF04156.9 GAM20887.1 - 0.071 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 GAM20887.1 - 0.38 10.5 0.2 0.38 10.5 0.1 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper PspB PF06667.7 GAM20887.1 - 8.1 6.4 7.1 15 5.6 0.8 2.5 1 1 1 2 2 2 0 Phage shock protein B Actin PF00022.14 GAM20888.1 - 3.1e-117 391.3 0.0 3.2e-60 203.6 0.0 2.0 1 1 1 2 2 2 2 Actin ESSS PF10183.4 GAM20888.1 - 0.049 14.0 0.0 0.13 12.7 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Gelsolin PF00626.17 GAM20889.1 - 5.4e-43 144.5 0.0 9.9e-13 47.5 0.0 5.5 5 0 0 5 5 5 5 Gelsolin repeat DUF1900 PF08954.6 GAM20889.1 - 9.8e-31 106.0 0.0 2.9e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 GAM20889.1 - 1.1e-16 60.0 9.7 5.4e-10 38.7 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat VHP PF02209.14 GAM20889.1 - 9.1e-13 47.6 0.1 2.1e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.24 GAM20889.1 - 1.3e-09 38.2 0.1 0.0033 17.5 0.0 3.0 2 0 0 2 2 2 2 PH domain DUF1899 PF08953.6 GAM20889.1 - 4.4e-05 23.0 0.0 0.00012 21.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) YfhE PF14152.1 GAM20889.1 - 0.51 10.2 2.1 17 5.4 0.3 2.4 2 0 0 2 2 2 0 YfhE-like protein Imm15 PF15590.1 GAM20890.1 - 0.071 12.1 0.1 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 15 NMT PF01233.14 GAM20892.1 - 9e-78 259.4 0.2 1.4e-77 258.8 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 GAM20892.1 - 6.7e-71 237.6 0.0 1e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 GAM20892.1 - 1.5e-05 24.8 0.0 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM20892.1 - 0.0032 17.6 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain LRR_4 PF12799.2 GAM20893.1 - 0.027 14.0 0.1 0.56 9.8 0.0 2.5 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Copine PF07002.11 GAM20894.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Copine DDOST_48kD PF03345.9 GAM20895.1 - 8.3e-70 235.4 0.9 9.9e-70 235.1 0.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4419 PF14388.1 GAM20896.1 - 2.9e-103 345.1 0.2 3.7e-103 344.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) MreD PF04093.7 GAM20896.1 - 0.099 12.5 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 rod shape-determining protein MreD Kelch_6 PF13964.1 GAM20897.1 - 9.7e-14 50.8 0.5 0.002 18.2 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM20897.1 - 2.8e-11 43.0 1.5 0.00065 19.4 0.0 4.9 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM20897.1 - 4.2e-07 29.9 0.2 2.4 8.4 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM20897.1 - 5.7e-07 28.9 0.2 0.053 13.0 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 GAM20897.1 - 0.52 10.3 2.3 35 4.5 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Pkinase_Tyr PF07714.12 GAM20898.1 - 5.9e-49 166.4 0.0 1.1e-48 165.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM20898.1 - 3.3e-43 147.7 0.0 4.5e-41 140.7 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain RasGEF PF00617.14 GAM20898.1 - 8.9e-41 139.6 0.1 2.6e-40 138.1 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.24 GAM20898.1 - 9e-25 86.3 0.1 5.6e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Miro PF08477.8 GAM20898.1 - 2.5e-15 56.9 1.9 1.4e-14 54.5 0.1 2.8 2 0 0 2 2 2 1 Miro-like protein DEP PF00610.16 GAM20898.1 - 3.6e-13 49.0 0.0 3.4e-12 45.9 0.0 2.7 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRR_4 PF12799.2 GAM20898.1 - 1.4e-12 46.9 19.3 4.2e-06 26.2 3.6 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Ras PF00071.17 GAM20898.1 - 5.1e-12 45.4 0.5 1e-11 44.5 0.4 1.5 1 0 0 1 1 1 1 Ras family LRR_8 PF13855.1 GAM20898.1 - 2e-10 40.2 18.5 4.6e-06 26.2 5.7 3.1 2 0 0 2 2 2 2 Leucine rich repeat RasGEF_N PF00618.15 GAM20898.1 - 5.5e-10 39.2 3.6 6.5e-09 35.8 0.1 3.6 3 0 0 3 3 3 1 RasGEF N-terminal motif GRAM PF02893.15 GAM20898.1 - 8.9e-09 34.7 0.2 2.6e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 GRAM domain LRR_7 PF13504.1 GAM20898.1 - 0.0012 18.6 6.7 0.21 11.9 0.5 5.1 4 0 0 4 4 4 1 Leucine rich repeat ABC_tran PF00005.22 GAM20898.1 - 0.008 16.4 0.0 0.008 16.4 0.0 2.6 3 0 0 3 3 2 1 ABC transporter APH PF01636.18 GAM20898.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.18 GAM20898.1 - 0.023 14.6 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_1 PF00560.28 GAM20898.1 - 0.081 13.0 15.6 0.57 10.4 0.2 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat RcsC PF09456.5 GAM20899.1 - 9 6.0 16.6 2.7 7.7 1.4 4.3 5 0 0 5 5 5 0 RcsC Alpha-Beta-Loop (ABL) Ank_2 PF12796.2 GAM20901.1 - 1.4e-45 153.5 8.7 1e-10 41.7 0.2 6.2 2 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20901.1 - 1e-33 115.0 11.8 3.4e-06 27.4 0.0 9.0 7 1 0 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20901.1 - 2.1e-33 113.5 13.9 0.0016 18.6 0.1 13.1 3 2 11 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20901.1 - 3.8e-29 97.8 17.8 0.55 10.6 0.0 14.8 9 4 7 16 16 16 8 Ankyrin repeat Ank PF00023.25 GAM20901.1 - 7.9e-25 85.3 12.6 0.21 11.4 0.0 14.1 13 2 2 15 15 15 6 Ankyrin repeat HTH_22 PF13309.1 GAM20901.1 - 0.0057 16.3 0.0 5.4 6.8 0.0 3.7 3 0 0 3 3 3 1 HTH domain RNase_P_p30 PF01876.11 GAM20901.1 - 0.016 14.4 0.0 34 3.6 0.0 4.3 3 1 3 6 6 6 0 RNase P subunit p30 DUF2462 PF09495.5 GAM20901.1 - 0.17 12.6 0.2 25 5.7 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2462) Ank_2 PF12796.2 GAM20902.1 - 5.2e-107 350.4 89.0 1.2e-11 44.7 1.0 16.1 4 4 14 19 19 19 19 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20902.1 - 1.7e-84 276.8 53.6 3.6e-06 27.3 0.0 22.8 15 5 8 24 24 24 19 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20902.1 - 7.8e-71 232.5 71.5 0.00042 20.4 0.0 35.1 5 3 32 37 37 37 23 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20902.1 - 2.2e-54 175.9 65.2 0.00012 22.0 0.0 32.6 23 8 14 37 37 35 11 Ankyrin repeat Ank PF00023.25 GAM20902.1 - 2.8e-50 165.6 61.2 0.0062 16.3 0.0 33.2 34 3 3 37 37 36 12 Ankyrin repeat DUF2790 PF10976.3 GAM20902.1 - 2.7e-07 30.2 4.1 7 6.5 0.0 8.3 7 1 1 8 8 8 1 Protein of unknown function (DUF2790) HTH_22 PF13309.1 GAM20902.1 - 0.00013 21.6 0.0 1.3 8.7 0.0 5.5 4 0 0 4 4 3 1 HTH domain Rbsn PF11464.3 GAM20902.1 - 0.00018 20.9 3.0 82 2.8 0.0 9.3 12 0 0 12 12 12 0 Rabenosyn Rab binding domain DUF2713 PF10897.3 GAM20902.1 - 0.0073 15.5 0.0 3.9 6.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2713) LEA_5 PF00477.12 GAM20902.1 - 0.015 15.5 0.2 3.6 7.8 0.0 3.2 2 0 0 2 2 2 0 Small hydrophilic plant seed protein DUF2462 PF09495.5 GAM20902.1 - 0.027 15.2 4.4 62 4.4 0.0 8.2 11 2 2 13 13 9 0 Protein of unknown function (DUF2462) RNase_P_p30 PF01876.11 GAM20902.1 - 0.048 12.9 0.0 3.6 6.8 0.0 4.1 4 1 1 5 5 5 0 RNase P subunit p30 RPOL_N PF14700.1 GAM20902.1 - 0.052 12.7 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal DUF3322 PF11795.3 GAM20902.1 - 0.98 9.0 2.6 1.1e+02 2.3 0.0 4.8 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Podoplanin PF05808.6 GAM20904.1 - 0.0068 15.9 1.1 0.019 14.5 0.7 1.8 1 0 0 1 1 1 1 Podoplanin YcgR PF07317.7 GAM20904.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Flagellar regulator YcgR PepSY_TM_2 PF13703.1 GAM20904.1 - 0.14 12.3 2.3 0.53 10.4 1.6 2.0 1 1 0 1 1 1 0 PepSY-associated TM helix SKG6 PF08693.5 GAM20904.1 - 0.25 10.6 7.5 0.61 9.4 5.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 GAM20904.1 - 0.48 10.1 2.2 1 9.0 1.6 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4006 PF13179.1 GAM20904.1 - 3.8 7.1 6.0 0.5 9.9 0.1 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF4006) FUN14 PF04930.10 GAM20904.1 - 5.1 7.4 8.4 0.74 10.1 1.5 2.5 2 0 0 2 2 2 0 FUN14 family Ank_5 PF13857.1 GAM20905.1 - 3.1e-10 39.9 3.0 0.0052 17.0 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM20905.1 - 5.3e-09 36.3 1.3 2.5e-08 34.1 0.7 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20905.1 - 8.3e-08 32.5 4.0 1.4e-05 25.4 0.5 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20905.1 - 6.4e-06 25.9 4.8 0.064 13.5 0.1 4.7 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.25 GAM20905.1 - 0.0014 18.3 1.4 0.14 12.0 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeat HupH_C PF04809.8 GAM20905.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Ank_2 PF12796.2 GAM20906.1 - 4.9e-47 158.1 12.4 4.2e-10 39.8 0.1 6.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20906.1 - 8.8e-33 112.0 4.7 7.3e-06 26.3 0.0 8.7 5 4 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20906.1 - 3.3e-32 109.7 8.6 0.092 13.0 0.0 12.2 1 1 10 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20906.1 - 1.9e-29 98.7 6.1 0.1 12.9 0.0 11.6 9 3 3 12 12 12 6 Ankyrin repeat Ank PF00023.25 GAM20906.1 - 2e-23 80.9 6.0 0.23 11.3 0.0 11.8 10 1 2 12 12 12 7 Ankyrin repeat HTH_22 PF13309.1 GAM20906.1 - 0.055 13.2 0.0 5.9 6.7 0.0 3.8 4 0 0 4 4 4 0 HTH domain Kunitz_BPTI PF00014.18 GAM20906.1 - 0.16 12.1 0.8 13 6.1 0.0 3.5 4 1 0 4 4 4 0 Kunitz/Bovine pancreatic trypsin inhibitor domain APP_Cu_bd PF12924.2 GAM20906.1 - 0.82 10.2 6.4 1.4 9.4 0.1 3.9 5 0 0 5 5 5 0 Copper-binding of amyloid precursor, CuBD Rap_GAP PF02145.10 GAM20907.1 - 3.5e-57 192.8 0.3 6.1e-57 192.0 0.2 1.4 1 0 0 1 1 1 1 Rap/ran-GAP CNH PF00780.17 GAM20907.1 - 3.3e-37 128.4 0.0 5.8e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 CNH domain PsbM PF05151.7 GAM20908.1 - 0.032 13.8 0.9 0.053 13.1 0.6 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) GTP_EFTU PF00009.22 GAM20911.1 - 3.4e-52 176.6 0.2 5.4e-52 175.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAM20911.1 - 6.5e-18 64.3 0.0 1.8e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM20911.1 - 2.5e-07 30.7 1.6 2.5e-07 30.7 1.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM20911.1 - 2.7e-05 24.0 0.1 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM20911.1 - 5e-05 23.7 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 GAM20911.1 - 0.0016 17.5 0.1 0.0036 16.3 0.0 1.5 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 GAM20911.1 - 0.0021 17.2 0.0 0.0021 17.2 0.0 2.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 GAM20911.1 - 0.0024 17.7 0.0 0.065 13.0 0.0 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 GAM20911.1 - 0.0063 15.8 0.1 0.061 12.6 0.1 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 GAM20911.1 - 0.014 14.2 0.2 5.2 5.7 0.0 3.0 3 0 0 3 3 3 0 ArgK protein EFG_II PF14492.1 GAM20911.1 - 0.024 14.4 0.2 0.078 12.8 0.1 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II PWWP PF00855.12 GAM20912.1 - 1.5e-10 41.1 2.6 6.1e-10 39.1 0.0 3.1 3 0 0 3 3 3 1 PWWP domain FMO-like PF00743.14 GAM20913.1 - 7.9e-59 199.2 0.0 1.1e-58 198.7 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM20913.1 - 3e-26 92.7 0.0 1.3e-24 87.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM20913.1 - 1.8e-12 46.8 1.2 1.6e-10 40.4 0.2 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 GAM20913.1 - 9.7e-12 45.1 0.0 2.1e-09 37.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM20913.1 - 1.3e-11 44.5 0.0 4.8e-10 39.4 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 GAM20913.1 - 1e-06 28.6 0.0 2.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 GAM20913.1 - 2.6e-06 27.7 0.0 0.013 15.8 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM20913.1 - 0.00013 21.1 0.0 0.002 17.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 GAM20913.1 - 0.0002 20.4 0.0 0.014 14.3 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM20913.1 - 0.0006 19.0 0.0 0.048 12.7 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 GAM20913.1 - 0.00066 18.2 0.0 0.0015 17.0 0.0 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 GAM20913.1 - 0.0015 17.4 0.0 0.21 10.4 0.0 2.1 1 1 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 GAM20913.1 - 0.0027 16.8 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2183 PF09949.4 GAM20913.1 - 0.096 12.6 0.0 9 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) COPIIcoated_ERV PF07970.7 GAM20914.1 - 2.1e-73 246.5 0.8 3.9e-73 245.7 0.6 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAM20914.1 - 3e-35 120.0 0.2 3e-35 120.0 0.1 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GalKase_gal_bdg PF10509.4 GAM20919.1 - 6.3e-22 76.6 0.1 1.1e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 GAM20919.1 - 4.2e-14 52.4 0.5 3.7e-13 49.4 0.0 2.5 2 1 1 3 3 3 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 GAM20919.1 - 6.8e-12 45.2 6.1 8.9e-12 44.8 0.1 2.9 3 0 0 3 3 3 1 GHMP kinases N terminal domain LRV PF01816.12 GAM20920.1 - 1.2 9.5 3.9 0.75 10.1 0.4 2.5 2 1 1 3 3 3 0 Leucine rich repeat variant SH3_1 PF00018.23 GAM20921.1 - 3.7e-21 74.2 4.0 7.2e-13 47.7 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 GAM20921.1 - 1.5e-18 66.0 3.3 5.4e-09 35.5 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 GAM20921.1 - 2.7e-18 65.2 0.4 2.6e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain Glutaminase PF04960.10 GAM20921.1 - 2.2e-17 62.9 0.6 7e-17 61.3 0.4 1.7 1 1 0 1 1 1 1 Glutaminase CS PF04969.11 GAM20921.1 - 5.5e-08 33.2 0.1 1.4e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 CS domain DUF3630 PF12305.3 GAM20921.1 - 0.26 11.2 0.0 1 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3630) Ras PF00071.17 GAM20922.1 - 9.7e-52 174.6 0.0 1.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM20922.1 - 1.3e-17 64.3 0.0 2.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM20922.1 - 2.6e-11 43.0 0.0 3.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM20922.1 - 2.9e-07 30.0 0.0 4.4e-06 26.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM20922.1 - 0.0074 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM20922.1 - 0.032 13.3 0.0 0.063 12.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ctr PF04145.10 GAM20923.1 - 2.1e-29 102.4 5.3 2.6e-29 102.1 3.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TrbL PF04610.9 GAM20923.1 - 0.084 12.5 6.4 2.2 7.9 0.1 2.1 1 1 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein IP_trans PF02121.13 GAM20925.1 - 2.5e-98 328.2 1.2 2.8e-98 328.1 0.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Cytokin_check_N PF10407.4 GAM20926.1 - 0.079 12.5 0.0 0.36 10.4 0.0 2.1 1 1 1 2 2 2 0 Cdc14 phosphatase binding protein N-terminus EF-hand_1 PF00036.27 GAM20927.1 - 5.8e-13 47.1 0.5 1e-05 24.4 0.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAM20927.1 - 4.3e-12 44.8 0.4 1.3e-06 27.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAM20927.1 - 9.4e-09 35.2 0.1 1.2e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM20927.1 - 2.4e-08 33.4 0.1 5.3e-08 32.3 0.0 1.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM20927.1 - 8.6e-07 28.0 0.7 0.0014 17.9 0.1 2.3 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 GAM20927.1 - 0.0022 18.0 0.0 0.0024 17.8 0.0 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 GAM20927.1 - 0.0097 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain ELO PF01151.13 GAM20928.1 - 1.2e-41 142.7 5.6 4.8e-28 98.1 1.0 2.0 2 0 0 2 2 2 2 GNS1/SUR4 family Na_Ca_ex PF01699.19 GAM20930.1 - 5e-19 68.2 47.1 2.7e-12 46.4 10.7 4.4 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAM20930.1 - 1.3e-13 51.1 11.2 1.3e-13 51.1 7.8 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF307) Kelch_3 PF13415.1 GAM20930.1 - 0.46 10.7 2.7 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Galactose oxidase, central domain TAFII55_N PF04658.8 GAM20932.1 - 3.5e-32 111.1 0.9 1.6e-31 108.9 0.1 2.6 2 0 0 2 2 2 1 TAFII55 protein conserved region Vps51 PF08700.6 GAM20932.1 - 0.039 13.7 0.4 0.039 13.7 0.3 2.2 2 0 0 2 2 2 0 Vps51/Vps67 AA_permease_2 PF13520.1 GAM20933.1 - 1.7e-48 165.2 50.1 1.7e-48 165.2 34.7 1.9 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 GAM20933.1 - 2.7e-42 144.7 42.7 2.7e-42 144.7 29.6 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 GAM20933.1 - 1.3e-18 66.6 2.8 1.3e-18 66.6 1.9 3.6 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.8 GAM20933.1 - 0.0012 17.5 20.8 0.0012 17.5 14.4 2.8 3 1 0 3 3 3 1 Spore germination protein Ammonium_transp PF00909.16 GAM20934.1 - 2.5e-96 322.6 36.7 2.9e-96 322.3 25.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family IF4E PF01652.13 GAM20935.1 - 3.9e-41 140.3 0.1 9.2e-41 139.1 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PBP1_TM PF14812.1 GAM20936.1 - 4.9 7.5 9.3 13 6.1 0.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TSA PF03249.8 GAM20937.1 - 0.0077 14.8 0.7 0.0098 14.4 0.5 1.1 1 0 0 1 1 1 1 Type specific antigen TFIIA PF03153.8 GAM20937.1 - 0.092 12.6 11.5 0.15 11.9 8.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 GAM20937.1 - 0.25 10.8 4.6 0.44 10.0 3.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 GAM20937.1 - 0.29 10.9 5.2 0.5 10.1 3.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 GAM20937.1 - 2.7 7.6 10.8 3.8 7.1 7.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2076 PF09849.4 GAM20937.1 - 3.2 7.7 10.1 5.7 6.9 7.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ThiF PF00899.16 GAM20938.1 - 1.8e-10 40.7 0.0 7e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 ThiF family NUDIX PF00293.23 GAM20939.1 - 2.7e-16 59.4 0.0 4.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C3HC4_3 PF13920.1 GAM20939.1 - 0.044 13.4 0.7 4.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM20939.1 - 0.078 12.8 0.3 8.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Ring finger domain Nitr_red_bet_C PF14711.1 GAM20939.1 - 0.088 12.3 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal zf-Di19 PF05605.7 GAM20939.1 - 0.24 11.5 1.5 1.3 9.1 1.0 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF2450 PF10475.4 GAM20940.1 - 8.8e-73 244.7 12.9 8.8e-73 244.7 9.0 2.5 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 GAM20940.1 - 1.9e-64 217.6 1.1 1.9e-64 217.6 0.7 2.8 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) DUF3010 PF11215.3 GAM20940.1 - 0.014 15.3 0.8 0.034 14.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) Ank_2 PF12796.2 GAM20941.1 - 2e-33 114.5 26.5 2.5e-10 40.5 1.4 6.3 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20941.1 - 1.2e-18 66.6 21.0 0.00014 22.0 0.2 10.9 6 3 6 12 12 12 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20941.1 - 1.9e-17 61.5 20.4 0.046 13.9 0.1 11.5 12 1 1 13 13 13 6 Ankyrin repeat Ank_4 PF13637.1 GAM20941.1 - 3.5e-17 62.4 16.8 0.00067 20.1 0.1 9.2 8 3 5 13 13 13 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM20941.1 - 6.4e-14 50.9 26.0 0.0091 15.7 0.2 9.9 10 2 1 11 11 11 5 Ankyrin repeat DUF3447 PF11929.3 GAM20941.1 - 5.4e-09 35.7 3.9 0.22 11.3 0.0 6.0 2 2 4 7 7 7 3 Domain of unknown function (DUF3447) WH2 PF02205.15 GAM20942.1 - 8.4e-07 28.3 0.6 0.84 9.3 0.0 3.3 3 0 0 3 3 3 3 WH2 motif Ank_2 PF12796.2 GAM20943.1 - 3.6e-12 46.4 0.0 8.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM20943.1 - 1.8e-11 43.8 0.0 3.2e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM20943.1 - 4.9e-10 38.7 0.0 1.9e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 GAM20943.1 - 2.7e-09 36.3 0.0 0.0022 18.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAM20943.1 - 1.7e-07 31.5 0.0 0.0011 19.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-FCS PF06467.9 GAM20943.1 - 0.023 14.3 1.0 0.076 12.6 0.7 1.9 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Ribosomal_S2 PF00318.15 GAM20943.1 - 6.7 5.8 11.2 0.28 10.3 2.8 2.1 3 0 0 3 3 3 0 Ribosomal protein S2 Bud13 PF09736.4 GAM20943.1 - 7.4 6.8 29.0 1.7 8.9 2.5 2.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Asp-B-Hydro_N PF05279.6 GAM20943.1 - 7.7 6.2 20.9 1.4 8.7 7.6 2.4 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Pkinase_Tyr PF07714.12 GAM20944.1 - 6.4e-51 172.9 0.0 1.1e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM20944.1 - 1e-46 159.2 0.0 2.4e-46 157.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAM20944.1 - 3.2e-05 23.7 0.0 0.00044 20.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM20944.1 - 6.3e-05 22.0 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like F-box-like PF12937.2 GAM20944.1 - 0.0086 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM20944.1 - 0.02 14.5 0.2 0.06 13.0 0.2 1.8 1 0 0 1 1 1 0 F-box domain Kdo PF06293.9 GAM20944.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.1 GAM20945.1 - 0.00035 20.2 2.4 1.3 8.8 0.0 4.1 4 0 0 4 4 4 2 Leucine rich repeat EGF_2 PF07974.8 GAM20945.1 - 0.00064 19.8 14.3 0.0017 18.4 9.9 1.8 1 0 0 1 1 1 1 EGF-like domain LRR_4 PF12799.2 GAM20945.1 - 0.0007 19.1 6.5 0.45 10.2 0.0 4.3 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) Epiglycanin_C PF14654.1 GAM20945.1 - 0.012 15.6 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region EGF PF00008.22 GAM20945.1 - 0.025 14.5 7.5 0.055 13.4 5.2 1.6 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.28 GAM20945.1 - 0.061 13.3 4.6 0.28 11.3 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat EB PF01683.13 GAM20945.1 - 0.09 12.8 8.2 0.23 11.5 5.7 1.6 1 0 0 1 1 1 0 EB module LRR_7 PF13504.1 GAM20945.1 - 0.13 12.5 3.3 12 6.5 0.0 4.5 4 0 0 4 4 4 0 Leucine rich repeat EGF_2 PF07974.8 GAM20946.1 - 0.0048 17.0 11.6 0.017 15.2 8.1 2.0 1 0 0 1 1 1 1 EGF-like domain DUF3188 PF11384.3 GAM20946.1 - 0.94 9.1 6.4 0.29 10.7 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Aa_trans PF01490.13 GAM20947.1 - 1.8e-14 53.0 43.6 1.7e-08 33.3 23.6 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TPP_enzyme_N PF02776.13 GAM20948.1 - 8.2e-41 139.3 0.1 5.6e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 GAM20948.1 - 1.2e-29 102.8 0.0 2.3e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 GAM20948.1 - 5.6e-19 68.2 0.2 1.7e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GpcrRhopsn4 PF10192.4 GAM20949.1 - 3.6e-50 170.5 31.9 3.6e-50 170.5 22.1 1.6 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF2427 PF10348.4 GAM20949.1 - 0.009 15.5 1.9 0.009 15.5 1.3 3.8 2 1 0 4 4 4 1 Domain of unknown function (DUF2427) Pkinase PF00069.20 GAM20950.1 - 2e-77 259.8 0.0 2.4e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM20950.1 - 6.8e-41 140.0 0.0 8.4e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM20950.1 - 6.5e-08 31.8 0.0 2.7e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 GAM20950.1 - 0.0026 17.1 0.0 0.005 16.2 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM20950.1 - 0.0053 15.8 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM20950.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RasGEF PF00617.14 GAM20951.1 - 2.3e-55 187.2 0.2 2.3e-55 187.2 0.2 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 GAM20951.1 - 8.6e-18 64.3 1.6 3.2e-16 59.3 0.3 4.7 5 1 0 5 5 5 2 RasGEF N-terminal motif F-box-like PF12937.2 GAM20951.1 - 1.7e-13 50.0 6.3 1e-07 31.5 1.1 3.3 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 GAM20951.1 - 9.6e-09 34.6 3.0 0.00011 21.7 0.5 3.4 3 0 0 3 3 3 2 F-box domain Mucin PF01456.12 GAM20951.1 - 0.0016 18.1 6.6 0.0016 18.1 4.6 6.3 5 1 2 7 7 7 1 Mucin-like glycoprotein Cna_B PF05738.8 GAM20953.1 - 5.5e-07 29.2 0.4 5.5e-07 29.2 0.2 1.7 2 0 0 2 2 2 1 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM20953.1 - 0.0074 16.3 0.9 0.011 15.7 0.6 1.4 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SAPS PF04499.10 GAM20956.1 - 4.4e-08 32.2 1.9 1.2e-06 27.4 0.1 8.0 5 4 1 6 6 6 3 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 GAM20956.1 - 7.6e-05 21.3 40.5 7.6e-05 21.3 28.1 3.7 3 1 1 4 4 4 1 Microtubule-binding protein MIP-T3 Zip PF02535.17 GAM20957.1 - 0.051 12.5 0.1 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 GAM20957.1 - 0.88 7.9 11.7 1.6 7.0 8.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NMN_transporter PF04973.7 GAM20957.1 - 1.2 8.5 5.3 8.2 5.8 0.0 2.9 2 1 1 3 3 3 0 Nicotinamide mononucleotide transporter DUF1840 PF08895.6 GAM20957.1 - 2.8 7.9 6.6 4.4 7.3 3.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) DUF2246 PF10229.4 GAM20957.1 - 6.6 5.9 9.5 13 4.9 6.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) Lyase_8 PF02278.13 GAM20958.1 - 3.6e-37 128.1 2.8 3.6e-37 128.1 1.9 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_C PF02884.12 GAM20958.1 - 1.5e-12 47.3 0.5 6e-12 45.4 0.4 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Lyase_8_N PF08124.6 GAM20958.1 - 1.7e-12 46.9 2.0 3.1e-12 46.0 1.4 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain PCNA_N PF00705.13 GAM20958.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain TMEM154 PF15102.1 GAM20958.1 - 1.1 8.9 6.2 2.2 7.9 4.3 1.5 1 0 0 1 1 1 0 TMEM154 protein family Ank_2 PF12796.2 GAM20960.1 - 1.9e-12 47.3 6.0 0.2 11.9 0.3 8.9 5 4 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20960.1 - 0.00085 19.7 5.1 7.8 7.1 0.2 6.7 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20960.1 - 0.0011 19.1 0.6 71 3.8 0.0 6.0 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20960.1 - 0.78 10.1 27.0 7.8 7.0 0.1 10.6 13 1 1 14 14 14 0 Ankyrin repeat DNA_pol_A_exo1 PF01612.15 GAM20961.1 - 1.9e-44 151.2 0.1 4.1e-44 150.1 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 GAM20961.1 - 3.8e-15 55.3 0.0 8.9e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Ras PF00071.17 GAM20962.1 - 4.8e-61 204.8 0.1 5.5e-61 204.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM20962.1 - 4.4e-20 72.3 0.0 8.4e-20 71.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM20962.1 - 2.6e-11 43.0 0.1 3.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM20962.1 - 9.4e-06 24.9 0.0 1.2e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM20962.1 - 4.6e-05 22.9 0.0 8.6e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM20962.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM20962.1 - 0.0082 15.4 0.1 0.055 12.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF1537 PF07005.6 GAM20962.1 - 0.065 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 AAA_22 PF13401.1 GAM20962.1 - 0.11 12.5 0.0 0.95 9.6 0.0 2.1 1 1 0 2 2 2 0 AAA domain Spore_permease PF03845.8 GAM20963.1 - 1.3 7.6 7.9 0.65 8.5 0.0 2.0 2 0 0 2 2 2 0 Spore germination protein Adeno_E3_14_5 PF04834.7 GAM20964.1 - 0.091 13.1 0.4 0.11 12.9 0.2 1.4 1 1 0 1 1 1 0 Early E3 14.5 kDa protein RRM_1 PF00076.17 GAM20965.1 - 1.4e-15 56.6 0.3 2.3e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM20965.1 - 1.3e-12 47.5 0.1 2.2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20965.1 - 1.7e-08 34.1 0.1 3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAP65_ASE1 PF03999.7 GAM20965.1 - 9.2 4.7 11.1 12 4.3 7.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RRM_6 PF14259.1 GAM20966.1 - 3.9e-08 33.1 0.0 7.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM20966.1 - 3.8e-07 29.6 0.0 7.8e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM20966.1 - 5.9e-06 26.0 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChlamPMP_M PF07548.6 GAM20966.1 - 1.5 8.5 8.3 0.18 11.5 2.4 1.9 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain Leader_Thr PF08254.6 GAM20966.1 - 9.7 6.0 12.1 0.27 10.9 3.6 2.0 2 0 0 2 2 2 0 Threonine leader peptide V-SNARE PF05008.10 GAM20967.1 - 0.0002 21.4 2.6 0.0002 21.4 1.8 2.5 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 GAM20967.1 - 0.001 18.7 2.3 0.0055 16.3 0.4 2.3 2 1 0 2 2 2 1 Sec20 V-SNARE_C PF12352.3 GAM20967.1 - 0.001 19.0 3.1 0.0026 17.7 1.1 2.3 3 0 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.16 GAM20967.1 - 0.0078 15.8 5.9 0.0078 15.8 4.1 2.2 2 0 0 2 2 2 1 Synaptobrevin DUF3533 PF12051.3 GAM20967.1 - 0.011 14.5 0.2 0.013 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MtrF PF09472.5 GAM20967.1 - 0.061 12.5 0.7 0.14 11.3 0.5 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SNARE PF05739.14 GAM20967.1 - 0.25 11.0 11.3 0.16 11.6 3.9 2.9 3 0 0 3 3 3 0 SNARE domain DUF4199 PF13858.1 GAM20967.1 - 0.27 11.1 4.0 0.12 12.3 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SSFA2_C PF14723.1 GAM20967.1 - 0.3 10.8 3.9 0.96 9.1 1.6 2.3 1 1 2 3 3 3 0 Sperm-specific antigen 2 C-terminus MtrG PF04210.8 GAM20967.1 - 0.36 10.5 4.1 0.51 10.0 0.5 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G V_ATPase_I PF01496.14 GAM20967.1 - 0.42 8.4 9.1 0.14 9.9 4.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 GAM20967.1 - 0.72 9.5 6.1 0.41 10.3 0.6 2.5 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Vpu PF00558.14 GAM20967.1 - 1.7 8.2 8.6 0.45 10.0 3.3 2.1 2 0 0 2 2 2 0 Vpu protein ZapA PF05164.8 GAM20967.1 - 2 8.4 6.6 3.5 7.6 0.1 3.0 2 1 1 3 3 3 0 Cell division protein ZapA Tup_N PF08581.5 GAM20967.1 - 2.7 8.2 17.9 4.3 7.6 0.3 3.3 2 1 1 3 3 3 0 Tup N-terminal HisKA_3 PF07730.8 GAM20967.1 - 4.4 7.7 7.6 3.1 8.1 0.4 3.6 2 2 3 5 5 5 0 Histidine kinase ATG16 PF08614.6 GAM20967.1 - 4.7 6.9 11.1 28 4.4 7.7 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) LUC7 PF03194.10 GAM20967.1 - 9.3 5.6 9.5 1.8e+02 1.5 6.6 2.1 1 1 0 1 1 1 0 LUC7 N_terminus Adeno_PIX PF03955.9 GAM20967.1 - 9.7 6.7 6.8 11 6.6 1.5 2.4 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) LRR_6 PF13516.1 GAM20968.1 - 1.5e-20 70.8 47.3 0.049 13.7 0.7 13.1 13 0 0 13 13 13 9 Leucine Rich repeat LRR_4 PF12799.2 GAM20968.1 - 1.3e-11 43.8 44.0 0.0032 17.0 2.1 8.1 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM20968.1 - 9.4e-09 34.1 37.8 0.42 10.8 0.4 12.3 11 2 0 11 11 11 4 Leucine Rich Repeat F-box-like PF12937.2 GAM20968.1 - 0.0035 17.0 0.4 0.35 10.6 0.1 2.8 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 GAM20968.1 - 0.37 10.5 50.1 0.31 10.8 3.6 7.6 5 2 3 8 8 8 0 Leucine rich repeat LRR_7 PF13504.1 GAM20968.1 - 0.72 10.3 47.4 1.1 9.7 1.1 11.8 13 0 0 13 13 13 0 Leucine rich repeat TPR_1 PF00515.23 GAM20969.1 - 6.8e-63 205.8 21.5 5.4e-08 32.1 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 GAM20969.1 - 2.8e-56 187.0 34.1 3e-13 49.2 0.8 7.2 2 1 7 9 9 9 9 TPR repeat TPR_2 PF07719.12 GAM20969.1 - 3.3e-52 170.2 17.4 1.8e-05 24.2 0.0 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.1 GAM20969.1 - 3e-41 136.1 18.6 0.00045 19.8 1.1 10.6 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20969.1 - 1.8e-34 117.4 16.7 7.1e-07 29.0 0.1 7.1 3 1 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAM20969.1 - 1.1e-33 112.6 16.9 0.00053 19.9 0.0 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAM20969.1 - 1.5e-32 111.5 0.7 7.6e-07 29.6 0.0 6.9 2 1 6 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 GAM20969.1 - 6.5e-29 97.7 0.0 0.017 15.6 0.0 8.6 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 GAM20969.1 - 4e-25 85.5 7.3 0.017 14.8 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAM20969.1 - 2.2e-23 82.3 5.6 0.0013 19.0 0.0 5.9 3 1 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 GAM20969.1 - 7.5e-21 73.1 12.7 0.0043 17.4 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 GAM20969.1 - 4.4e-14 52.0 1.4 0.02 14.7 0.3 6.4 3 3 4 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM20969.1 - 6e-11 42.3 22.9 3.8e-06 26.9 0.9 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 GAM20969.1 - 3.2e-08 33.5 0.1 0.71 10.0 0.0 6.6 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM20969.1 - 2.4e-07 30.1 10.5 0.061 12.3 0.1 4.4 2 1 2 4 4 4 3 Tetratricopeptide repeat ChAPs PF09295.5 GAM20969.1 - 8.5e-06 24.7 1.1 0.075 11.7 0.0 3.5 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 GAM20969.1 - 0.00025 20.8 4.6 11 6.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.13 GAM20969.1 - 0.072 12.9 15.4 3.6 7.5 0.0 6.5 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 GAM20969.1 - 0.67 9.8 0.0 0.67 9.8 0.0 5.2 7 1 0 7 7 3 0 Tetratricopeptide repeat ORC3_N PF07034.6 GAM20970.1 - 3.6e-21 75.4 2.0 1.2e-20 73.7 1.4 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF164 PF02591.10 GAM20970.1 - 0.53 10.1 6.8 0.68 9.7 0.6 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain Ank_2 PF12796.2 GAM20971.1 - 1.3e-13 51.0 2.9 0.18 12.1 0.0 9.0 6 4 2 8 8 8 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM20971.1 - 8.6e-05 22.4 8.3 27 5.3 0.1 10.2 10 1 1 11 11 11 0 Ankyrin repeat Ank_4 PF13637.1 GAM20971.1 - 0.00016 22.0 4.4 26 5.4 0.1 8.3 8 1 1 9 9 9 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20971.1 - 0.00073 19.7 0.5 48 4.3 0.0 7.3 8 0 0 8 8 8 0 Ankyrin repeats (many copies) CENP-B_dimeris PF09026.5 GAM20971.1 - 0.052 13.7 8.5 0.15 12.3 5.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 GAM20971.1 - 0.13 11.8 3.9 0.24 10.9 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Ank PF00023.25 GAM20971.1 - 0.29 11.0 6.3 57 3.7 0.0 6.4 9 0 0 9 9 9 0 Ankyrin repeat RNA_pol_3_Rpc31 PF11705.3 GAM20971.1 - 0.74 9.7 8.4 1.3 8.9 5.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 GAM20971.1 - 0.83 8.3 7.9 1.2 7.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 GAM20971.1 - 3.2 7.5 6.6 2.3 8.0 3.0 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF758 PF05527.6 GAM20972.1 - 1.9e-07 30.8 1.2 2.8e-07 30.3 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH PF00169.24 GAM20972.1 - 2.8e-06 27.4 0.0 5.2e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 GAM20972.1 - 0.00049 20.2 0.2 0.0012 18.9 0.1 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain p450 PF00067.17 GAM20972.1 - 0.019 13.4 0.1 0.028 12.9 0.1 1.2 1 0 0 1 1 1 0 Cytochrome P450 RdRP_3 PF00998.18 GAM20972.1 - 0.06 11.8 0.0 0.082 11.3 0.0 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase SET PF00856.23 GAM20973.1 - 1.5e-13 51.3 0.0 7.5e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 GAM20973.1 - 6.7e-11 41.6 2.5 3.1e-07 29.9 0.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM20973.1 - 1.6e-07 30.6 0.3 0.035 14.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM20973.1 - 3.4e-05 23.2 1.4 0.1 12.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-MYND PF01753.13 GAM20973.1 - 5.2e-05 23.0 0.8 5.2e-05 23.0 0.6 2.5 3 0 0 3 3 3 1 MYND finger TPR_16 PF13432.1 GAM20973.1 - 0.00082 19.9 0.0 0.0049 17.5 0.1 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM20973.1 - 0.079 12.9 0.2 0.72 9.8 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Ecl1 PF12855.2 GAM20973.1 - 0.62 9.3 5.4 1.6 8.0 3.8 1.8 1 1 0 1 1 1 0 Life-span regulatory factor Rab3-GTPase_cat PF13890.1 GAM20974.1 - 2.9e-42 143.8 0.9 2.9e-42 143.8 0.6 2.5 3 1 0 3 3 3 1 Rab3 GTPase-activating protein catalytic subunit Dishevelled PF02377.10 GAM20974.1 - 2.6 8.3 9.1 1.7 8.8 1.9 2.7 2 0 0 2 2 2 0 Dishevelled specific domain PH PF00169.24 GAM20975.1 - 7.9e-13 48.5 0.0 3.1e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM20975.1 - 2.9e-08 33.9 1.4 7.6e-07 29.3 1.0 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM20975.1 - 7.4e-08 32.3 0.1 0.0065 16.5 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 GAM20975.1 - 0.0086 15.9 0.6 1.3 8.9 0.0 2.5 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology Lactamase_B PF00753.22 GAM20976.1 - 2.9e-17 62.9 0.1 4.1e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM20976.1 - 9.8e-05 21.9 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain bZIP_Maf PF03131.12 GAM20976.1 - 0.15 12.3 2.0 15 5.9 0.3 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Kelch_6 PF13964.1 GAM20977.1 - 0.011 15.8 2.9 0.18 12.0 0.1 3.7 4 0 0 4 4 4 0 Kelch motif Kelch_3 PF13415.1 GAM20977.1 - 0.018 15.1 0.5 0.3 11.3 0.0 3.0 4 0 0 4 4 4 0 Galactose oxidase, central domain Glycos_transf_2 PF00535.21 GAM20978.1 - 1.4e-29 102.9 0.0 3.3e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_1 PF00534.15 GAM20978.1 - 3.4e-26 91.6 0.0 8.7e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.4 GAM20978.1 - 5.2e-18 65.1 0.1 1.1e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 GAM20978.1 - 1.8e-13 50.7 0.1 1.6e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_1_4 PF13692.1 GAM20978.1 - 1.3e-07 31.8 0.0 2.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAM20978.1 - 0.00039 20.6 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM20978.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Nepo_coat_N PF03689.10 GAM20978.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Glyco_trans_2_3 PF13632.1 GAM20978.1 - 0.069 12.8 0.1 0.32 10.6 0.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family group 2 GRDB PF07355.7 GAM20978.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) IncA PF04156.9 GAM20978.1 - 1.8 8.1 8.8 1.5 8.3 1.8 2.9 3 0 0 3 3 3 0 IncA protein AlcCBM31 PF11606.3 GAM20979.1 - 0.011 15.6 0.4 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Family 31 carbohydrate binding protein CBM49 PF09478.5 GAM20979.1 - 0.021 14.9 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 FNIP PF05725.7 GAM20980.1 - 1.2e-35 121.1 10.8 9e-10 38.3 0.9 6.9 4 1 4 9 9 9 7 FNIP Repeat FNIP PF05725.7 GAM20981.1 - 0.058 13.3 0.6 7.2 6.6 0.1 2.6 1 1 0 2 2 2 0 FNIP Repeat F-box-like PF12937.2 GAM20981.1 - 0.06 13.0 1.2 0.13 12.0 0.9 1.5 1 0 0 1 1 1 0 F-box-like PIN_2 PF10130.4 GAM20981.1 - 0.062 13.3 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 PIN domain F-box PF00646.28 GAM20981.1 - 0.24 11.1 2.8 0.53 10.0 1.9 1.6 1 0 0 1 1 1 0 F-box domain FNIP PF05725.7 GAM20982.1 - 3.5e-68 225.3 47.1 1.4e-11 44.1 0.1 11.4 5 3 5 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 GAM20982.1 - 0.0077 16.1 3.2 3.9 7.5 0.0 5.2 4 1 1 6 6 6 2 Protein of unknown function (DUF1769) DUF773 PF05600.7 GAM20984.1 - 2.3e-79 267.5 17.7 2.7e-79 267.2 12.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF773) DUF4535 PF15054.1 GAM20984.1 - 0.0077 15.6 0.9 0.069 12.5 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4535) PspB PF06667.7 GAM20984.1 - 0.014 15.3 2.4 0.049 13.5 1.7 2.0 1 0 0 1 1 1 0 Phage shock protein B Filament PF00038.16 GAM20984.1 - 0.066 12.6 12.7 0.046 13.1 4.0 2.3 2 0 0 2 2 2 0 Intermediate filament protein ATG16 PF08614.6 GAM20984.1 - 0.082 12.7 15.2 0.74 9.5 4.9 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 GAM20984.1 - 0.12 12.4 14.0 7.8 6.5 0.0 3.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit NAAA-beta PF15508.1 GAM20984.1 - 0.28 11.5 2.7 1.5 9.1 0.0 3.4 3 1 1 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Reo_sigmaC PF04582.7 GAM20984.1 - 0.33 10.0 3.8 2.5 7.1 0.7 2.6 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF4446 PF14584.1 GAM20984.1 - 2.5 7.9 7.6 2.6 7.8 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Syntaxin PF00804.20 GAM20984.1 - 2.6 8.2 16.8 0.31 11.2 0.4 3.3 2 1 0 2 2 2 0 Syntaxin Sec8_exocyst PF04048.9 GAM20984.1 - 3 7.4 13.0 10 5.7 0.5 2.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain TMF_DNA_bd PF12329.3 GAM20984.1 - 3.5 7.5 21.8 1.7 8.4 4.5 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RabGAP-TBC PF00566.13 GAM20985.1 - 1.5e-49 168.4 0.9 2.2e-49 167.8 0.6 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HAMP PF00672.20 GAM20986.1 - 4.7e-63 209.2 9.6 2e-08 34.3 0.1 8.3 8 0 0 8 8 8 7 HAMP domain Response_reg PF00072.19 GAM20986.1 - 3.6e-43 146.1 0.4 2.1e-27 95.3 0.3 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 GAM20986.1 - 4.5e-31 106.8 0.8 1.4e-30 105.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM20986.1 - 6.3e-21 74.1 3.3 3.9e-20 71.6 0.0 3.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain SpoIIID PF12116.3 GAM20986.1 - 8.6e-08 32.0 1.1 6.8 6.6 0.0 6.5 7 0 0 7 7 7 2 Stage III sporulation protein D TSC22 PF01166.13 GAM20986.1 - 9.5e-06 25.4 10.4 9.5 6.2 0.0 6.3 6 0 0 6 6 6 3 TSC-22/dip/bun family Tup_N PF08581.5 GAM20986.1 - 0.01 16.0 0.2 0.19 11.9 0.1 3.3 3 0 0 3 3 3 0 Tup N-terminal HTH_6 PF01418.12 GAM20986.1 - 0.069 12.8 1.8 49 3.7 0.0 4.8 6 0 0 6 6 6 0 Helix-turn-helix domain, rpiR family DUF948 PF06103.6 GAM20986.1 - 1.8 8.5 38.7 14 5.6 0.1 10.0 6 4 2 9 9 9 0 Bacterial protein of unknown function (DUF948) LSM PF01423.17 GAM20987.1 - 7.5e-17 60.6 1.5 1e-16 60.2 1.1 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 GAM20987.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) SM-ATX PF14438.1 GAM20987.1 - 0.02 14.8 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain FoP_duplication PF13865.1 GAM20987.1 - 9.5 6.7 9.7 14 6.1 6.7 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Conotoxin PF02950.12 GAM20988.1 - 0.048 14.4 0.0 0.065 14.0 0.0 1.3 1 0 0 1 1 1 0 Conotoxin DUF2085 PF09858.4 GAM20989.1 - 0.013 15.5 6.0 0.26 11.3 0.8 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF1180 PF06679.7 GAM20989.1 - 0.16 11.8 0.1 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2975 PF11188.3 GAM20989.1 - 1.4 8.6 18.4 8.9 6.0 7.9 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2975) VHP PF02209.14 GAM20990.1 - 8.7e-13 47.7 2.5 1.4e-12 47.0 1.8 1.4 1 0 0 1 1 1 1 Villin headpiece domain PV-1 PF06637.6 GAM20990.1 - 0.0048 15.5 1.6 0.0065 15.0 1.1 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF3166 PF11365.3 GAM20990.1 - 0.014 15.8 0.1 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) CENP-F_N PF10481.4 GAM20990.1 - 0.017 14.4 0.6 0.017 14.4 0.4 1.8 2 1 0 2 2 2 0 Cenp-F N-terminal domain FlaC_arch PF05377.6 GAM20990.1 - 0.027 14.3 0.6 0.027 14.3 0.4 1.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 GAM20990.1 - 0.068 12.6 2.3 0.15 11.5 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 GAM20990.1 - 0.13 12.2 3.4 0.22 11.5 2.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF566 PF04484.7 GAM20990.1 - 5.4 6.4 11.4 7.1 6.0 7.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ank_2 PF12796.2 GAM20991.1 - 5.6e-62 206.0 45.3 1.5e-09 38.0 0.6 9.6 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM20991.1 - 4.8e-48 160.7 27.0 3.1e-06 27.5 0.0 12.9 7 3 3 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM20991.1 - 5.3e-47 156.7 40.3 0.007 16.5 0.0 18.8 3 3 17 20 20 20 18 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM20991.1 - 8e-36 118.5 25.9 0.15 12.3 0.0 20.4 9 4 12 21 21 21 10 Ankyrin repeat Ank PF00023.25 GAM20991.1 - 5.9e-22 76.3 27.3 0.75 9.7 0.0 18.6 13 5 6 19 19 19 5 Ankyrin repeat DUF2790 PF10976.3 GAM20991.1 - 5.9e-05 22.7 11.7 3.7 7.4 0.0 7.4 6 1 1 8 8 8 2 Protein of unknown function (DUF2790) ENTH PF01417.15 GAM20991.1 - 0.0038 17.0 0.7 19 5.1 0.0 5.2 5 2 0 5 5 5 0 ENTH domain Clp1 PF06807.9 GAM20991.1 - 0.11 12.2 0.0 13 5.4 0.0 3.4 4 0 0 4 4 4 0 Pre-mRNA cleavage complex II protein Clp1 DAP3 PF10236.4 GAM20992.1 - 1.4e-10 40.6 0.0 5.8e-09 35.3 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 GAM20992.1 - 0.015 15.3 0.0 0.39 10.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM20992.1 - 0.034 14.9 0.1 0.38 11.5 0.0 2.5 2 1 1 3 3 3 0 AAA domain Zot PF05707.7 GAM20992.1 - 0.035 13.5 0.0 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DAP3 PF10236.4 GAM20993.1 - 2.5e-06 26.6 0.0 0.00016 20.7 0.0 2.9 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DAP3 PF10236.4 GAM20994.1 - 2.5e-05 23.3 0.2 0.0024 16.8 0.0 2.7 3 1 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 TrbC_Ftype PF09673.5 GAM20994.1 - 0.0091 15.5 0.1 19 4.8 0.0 3.3 2 1 1 3 3 3 3 Type-F conjugative transfer system pilin assembly protein Toxin_64 PF15542.1 GAM20995.1 - 0.056 14.0 2.8 0.14 12.7 1.9 1.8 1 0 0 1 1 1 0 Putative toxin 64 CCDC74_C PF14917.1 GAM20995.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal ATP-synt_F6 PF05511.6 GAM20995.1 - 0.2 11.5 0.7 0.48 10.3 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Scm3 PF10384.4 GAM20995.1 - 0.27 10.7 5.2 3.4 7.2 0.5 2.8 3 0 0 3 3 3 0 Centromere protein Scm3 DUF2701 PF10857.3 GAM20996.1 - 4.1 7.2 10.1 2.5 7.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) Pyr_redox_2 PF07992.9 GAM20997.1 - 8.9e-07 28.9 0.0 0.0085 15.9 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM20997.1 - 5.7e-06 26.5 0.1 0.0046 17.0 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM20997.1 - 0.0025 18.1 0.8 1.8 9.0 0.0 4.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 GAM20997.1 - 0.0033 17.6 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.1 GAM20997.1 - 0.0035 17.1 0.3 0.041 13.6 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 GAM20997.1 - 0.012 14.6 0.0 2.9 6.9 0.0 2.8 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 GAM20997.1 - 0.025 14.6 0.0 14 5.7 0.0 3.5 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Pox_VLTF3 PF04947.9 GAM20997.1 - 0.037 13.5 0.2 0.072 12.5 0.2 1.4 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like NAD_binding_8 PF13450.1 GAM20997.1 - 0.06 13.3 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FNIP PF05725.7 GAM20998.1 - 1.8e-107 351.0 18.4 1.1e-13 50.8 0.0 9.3 5 1 6 12 12 12 11 FNIP Repeat Peptidase_C37 PF05416.7 GAM20998.1 - 3.1 5.9 5.4 3.1 5.9 2.9 1.5 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Aminotran_3 PF00202.16 GAM20999.1 - 1.5e-98 329.8 0.0 1.8e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAM20999.1 - 4.5e-06 25.8 0.0 6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 GAM21000.1 - 2e-20 72.8 24.5 3e-20 72.2 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 GAM21000.1 - 2.6e-14 52.4 20.3 4.5e-14 51.6 14.0 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein BT1 PF03092.11 GAM21000.1 - 0.023 13.4 0.1 0.023 13.4 0.1 3.0 3 1 0 3 3 3 0 BT1 family Mob1_phocein PF03637.12 GAM21002.1 - 2.7e-50 170.4 0.5 3.1e-50 170.2 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_16 PF00722.16 GAM21003.1 - 0.0059 15.9 0.8 0.053 12.8 0.7 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 UMP1 PF05348.6 GAM21004.1 - 7.6e-25 87.3 0.4 8.9e-25 87.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Aldedh PF00171.17 GAM21005.1 - 1.6e-182 606.9 0.0 1.8e-182 606.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM21005.1 - 0.049 12.8 0.0 0.72 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ras PF00071.17 GAM21006.1 - 1.4e-50 170.8 0.2 1.7e-50 170.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21006.1 - 1.3e-17 64.3 0.4 2.5e-17 63.4 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM21006.1 - 2.1e-13 49.8 0.0 2.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM21006.1 - 3.9e-06 26.4 0.0 0.00023 20.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM21006.1 - 8.1e-06 25.1 0.1 1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM21006.1 - 0.0004 20.3 0.0 0.00074 19.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM21006.1 - 0.00069 18.8 0.0 0.00096 18.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAM21006.1 - 0.032 13.7 0.1 0.59 9.6 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 GAM21006.1 - 0.058 12.8 0.0 5.8 6.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TFIID-18kDa PF02269.11 GAM21007.1 - 1.1e-29 102.0 0.8 1.6e-29 101.5 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit SOBP PF15279.1 GAM21007.1 - 0.00037 20.9 5.5 0.00038 20.9 3.8 1.1 1 0 0 1 1 1 1 Sine oculis-binding protein CBFD_NFYB_HMF PF00808.18 GAM21007.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAM21007.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Pol_alpha_B_N PF08418.5 GAM21007.1 - 0.11 11.9 10.2 0.16 11.4 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CTDII PF01556.13 GAM21008.1 - 2.8e-25 88.0 0.6 3.8e-18 65.1 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 GAM21008.1 - 1.5e-21 75.8 0.8 2.6e-21 75.1 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain Stc1 PF12898.2 GAM21008.1 - 0.083 12.9 2.0 0.21 11.6 1.4 1.6 1 0 0 1 1 1 0 Stc1 domain Mitofilin PF09731.4 GAM21008.1 - 0.19 10.3 9.1 0.26 9.9 6.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2207 PF09972.4 GAM21010.1 - 0.17 10.4 5.9 4.9 5.6 0.0 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Tic20 PF09685.5 GAM21010.1 - 2.4 8.1 9.3 0.24 11.3 2.4 2.2 3 0 0 3 3 3 0 Tic20-like protein DUF4555 PF15093.1 GAM21011.1 - 5.6 5.7 5.4 14 4.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4555) Syndecan PF01034.15 GAM21011.1 - 8.4 6.1 6.4 14 5.4 0.2 2.8 2 1 1 3 3 3 0 Syndecan domain DUF3808 PF10300.4 GAM21012.1 - 8.9e-39 133.3 8.1 3.6e-37 128.0 2.9 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_12 PF13424.1 GAM21012.1 - 2.1e-11 43.5 0.3 2.9e-05 23.8 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21012.1 - 2.5e-11 42.5 0.0 0.0059 16.4 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21012.1 - 8.1e-09 34.7 2.9 0.0024 17.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM21012.1 - 1.3e-07 31.5 3.8 0.13 12.7 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21012.1 - 1.2e-06 28.0 4.9 0.0014 18.2 0.1 4.1 3 1 1 4 4 4 3 TPR repeat Apc3 PF12895.2 GAM21012.1 - 5.1e-06 26.5 11.8 0.011 15.8 0.1 4.7 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAM21012.1 - 0.00023 20.6 8.1 0.035 13.8 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21012.1 - 0.00073 19.9 0.0 4 8.3 0.0 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM21012.1 - 0.0048 17.5 0.0 0.47 11.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 GAM21012.1 - 0.0085 15.5 2.3 0.51 9.7 0.1 2.9 2 1 0 3 3 3 1 Foie gras liver health family 1 TPR_19 PF14559.1 GAM21012.1 - 0.0094 16.2 0.2 4.2 7.7 0.0 4.0 4 1 1 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.3 GAM21012.1 - 0.014 14.2 0.4 0.11 11.2 0.0 2.6 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 LRR_6 PF13516.1 GAM21013.1 - 1.6e-12 46.1 11.6 0.077 13.1 0.1 8.3 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 GAM21013.1 - 2.6e-09 36.5 8.5 0.0011 18.5 0.1 5.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM21013.1 - 5.3e-07 28.8 2.4 4.5 7.6 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 GAM21013.1 - 0.0042 16.7 6.0 0.13 12.0 0.6 4.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_7 PF13504.1 GAM21013.1 - 0.018 15.1 0.7 83 4.0 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat XRN_N PF03159.13 GAM21014.1 - 3e-32 111.8 0.5 6.1e-32 110.9 0.3 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus FG-GAP PF01839.18 GAM21015.1 - 1.8e-18 65.6 30.8 1.8e-07 30.6 0.7 6.0 7 0 0 7 7 7 4 FG-GAP repeat Zn_dep_PLPC PF00882.13 GAM21015.1 - 6.5e-14 51.9 0.1 1.1e-13 51.1 0.1 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.1 GAM21015.1 - 4.8e-12 46.0 10.7 8e-07 29.3 0.6 5.0 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.1 GAM21015.1 - 6.6e-05 22.8 14.9 0.13 12.3 0.3 6.0 6 0 0 6 6 6 2 FG-GAP repeat TcdB_toxin_midN PF12256.3 GAM21015.1 - 0.00025 20.5 7.6 1.2 8.5 0.0 5.0 3 1 1 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region Pmp3 PF01679.12 GAM21016.1 - 1.6e-21 75.7 11.1 1.8e-21 75.5 7.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.3 GAM21016.1 - 0.0086 15.7 0.6 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal GDI PF00996.13 GAM21017.1 - 6.6e-77 258.6 1.1 4.4e-76 255.9 0.8 2.0 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 GAM21017.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Alpha_kinase PF02816.13 GAM21019.1 - 1.1e-54 185.0 1.0 2.1e-54 184.0 0.7 1.6 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 GAM21019.1 - 4.8e-52 172.0 18.3 4.8e-09 35.7 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM21019.1 - 4e-09 35.1 16.7 0.017 13.2 0.1 5.8 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM21019.1 - 0.011 14.5 16.7 0.0056 15.4 4.8 3.2 2 1 0 2 2 2 0 Nup133 N terminal like TMEM191C PF15194.1 GAM21019.1 - 0.011 15.5 0.0 1.4 8.8 0.0 3.5 4 0 0 4 4 4 0 TMEM191C family PQQ_3 PF13570.1 GAM21019.1 - 0.059 13.6 0.9 1e+02 3.3 0.0 4.9 5 1 0 6 6 6 0 PQQ-like domain EF_assoc_2 PF08356.7 GAM21020.1 - 8.3e-25 86.3 0.0 4.9e-23 80.7 0.0 2.5 2 0 0 2 2 2 1 EF hand associated Miro PF08477.8 GAM21020.1 - 1.1e-20 74.3 0.2 3.9e-14 53.1 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Ras PF00071.17 GAM21020.1 - 7.7e-20 70.8 0.8 2.5e-19 69.2 0.1 2.2 2 0 0 2 2 2 1 Ras family EF_assoc_1 PF08355.7 GAM21020.1 - 5.6e-12 44.7 0.0 1.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.1 GAM21020.1 - 3.4e-07 30.3 0.1 0.038 14.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 GAM21020.1 - 3.6e-07 30.1 0.1 0.0037 17.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 GAM21020.1 - 9.3e-07 27.7 0.1 0.0054 15.9 0.0 2.6 2 0 0 2 2 2 2 EF hand Arf PF00025.16 GAM21020.1 - 1.6e-06 27.5 0.8 5.1e-05 22.5 0.2 3.0 2 1 0 2 2 2 1 ADP-ribosylation factor family EF-hand_6 PF13405.1 GAM21020.1 - 3.2e-06 26.5 0.2 0.015 15.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain DUF258 PF03193.11 GAM21020.1 - 6.4e-06 25.4 0.1 0.097 11.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 EF-hand_5 PF13202.1 GAM21020.1 - 1.1e-05 24.4 2.6 0.00062 18.9 0.1 2.5 2 0 0 2 2 2 1 EF hand Septin PF00735.13 GAM21020.1 - 2.2e-05 23.6 0.2 0.022 13.7 0.0 2.6 2 1 0 2 2 2 2 Septin GTP_EFTU PF00009.22 GAM21020.1 - 2.6e-05 23.7 1.9 0.0024 17.3 0.7 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 GAM21020.1 - 6e-05 23.3 0.0 0.62 10.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA PF00004.24 GAM21020.1 - 6.1e-05 23.2 0.0 0.67 10.1 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) EF-hand_8 PF13833.1 GAM21020.1 - 0.0012 18.3 0.2 0.043 13.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_16 PF13191.1 GAM21020.1 - 0.0014 18.6 0.9 1.8 8.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.1 GAM21020.1 - 0.0015 18.1 0.9 0.08 12.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM21020.1 - 0.0019 18.2 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM21020.1 - 0.0042 17.2 0.4 0.48 10.5 0.0 3.1 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 GAM21020.1 - 0.005 16.3 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 GAM21020.1 - 0.0058 16.7 0.0 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase SPARC_Ca_bdg PF10591.4 GAM21020.1 - 0.01 15.8 0.1 2.3 8.2 0.1 3.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_29 PF13555.1 GAM21020.1 - 0.015 14.8 2.3 1.3 8.5 0.2 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain NACHT PF05729.7 GAM21020.1 - 0.017 14.7 0.1 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 NACHT domain Dynamin_N PF00350.18 GAM21020.1 - 0.017 14.9 0.7 3.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Dynamin family cobW PF02492.14 GAM21020.1 - 0.028 13.8 1.8 10 5.5 0.3 3.4 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 GAM21020.1 - 0.035 14.0 0.0 8.8 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAM21020.1 - 0.043 13.5 3.3 0.54 9.9 0.1 2.7 2 1 1 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 GAM21020.1 - 0.043 12.9 0.1 4 6.4 0.0 2.4 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.13 GAM21020.1 - 0.044 13.0 0.8 4.4 6.5 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_33 PF13671.1 GAM21020.1 - 0.046 13.5 0.1 13 5.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAM21020.1 - 0.048 13.1 1.0 0.87 9.0 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 GAM21020.1 - 0.055 13.7 0.0 0.65 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 GAM21020.1 - 0.087 12.2 0.1 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Virulence-associated protein E Guanylate_kin PF00625.16 GAM21020.1 - 0.095 12.1 0.1 2.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase DUF815 PF05673.8 GAM21020.1 - 0.12 11.3 0.0 7 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 GAM21020.1 - 0.16 11.4 0.1 5 6.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 GAM21020.1 - 0.25 10.8 2.8 3.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 GAM21020.1 - 0.65 9.6 3.6 2.3 7.8 0.0 3.3 5 0 0 5 5 3 0 NTPase Histone PF00125.19 GAM21022.1 - 9.1e-20 70.5 0.6 5.5e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM21022.1 - 4.5e-06 26.6 0.0 0.0085 16.1 0.0 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.22 GAM21023.1 - 1.2e-65 217.2 1.5 4.6e-25 87.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FPL PF09758.4 GAM21024.1 - 1.2e-56 190.5 11.8 2.7e-56 189.5 8.2 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein HCaRG PF07258.9 GAM21025.1 - 8.5e-27 93.8 0.2 1.1e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 HCaRG protein FliD_N PF02465.13 GAM21025.1 - 0.08 13.3 2.7 0.1 13.0 1.0 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Peptidase_M13_N PF05649.8 GAM21025.1 - 0.093 11.7 0.9 0.18 10.8 0.2 1.8 2 1 0 2 2 2 0 Peptidase family M13 Polyketide_cyc PF03364.15 GAM21026.1 - 1.6e-20 73.4 0.1 2.3e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 GAM21026.1 - 1.5e-07 31.6 0.0 2.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ribosomal_S4 PF00163.14 GAM21027.1 - 1.4e-25 89.4 1.2 2.8e-25 88.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAM21027.1 - 3.1e-11 42.5 0.5 9.4e-11 40.9 0.3 1.9 1 0 0 1 1 1 1 S4 domain Nnf1 PF03980.9 GAM21028.1 - 2e-12 47.0 3.9 3.5e-12 46.2 2.7 1.4 1 1 0 1 1 1 1 Nnf1 Nexin_C PF08628.7 GAM21028.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.7 1 1 0 1 1 1 0 Sorting nexin C terminal ADIP PF11559.3 GAM21028.1 - 0.068 13.0 6.4 0.12 12.3 4.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding WXG100 PF06013.7 GAM21028.1 - 0.076 13.0 0.4 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG Acetyltransf_11 PF13720.1 GAM21028.1 - 0.084 13.1 0.6 0.26 11.5 0.2 1.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Cortex-I_coil PF09304.5 GAM21028.1 - 0.12 12.4 6.9 0.038 14.0 2.9 1.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil DivIC PF04977.10 GAM21028.1 - 0.19 11.2 4.3 0.34 10.4 3.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Rootletin PF15035.1 GAM21028.1 - 0.66 9.9 7.7 1.5 8.8 3.5 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.13 GAM21028.1 - 0.75 9.5 4.7 0.48 10.1 1.9 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 GAM21028.1 - 2.6 8.0 8.6 1.1 9.2 2.8 2.4 2 1 1 3 3 3 0 bZIP transcription factor PTPA PF03095.10 GAM21031.1 - 3.5e-109 364.5 0.0 4e-109 364.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GAS2 PF02187.12 GAM21032.1 - 2e-07 30.6 0.0 6.9e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain GAS PF13851.1 GAM21032.1 - 0.0038 16.4 14.0 0.0038 16.4 9.7 2.8 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.1 GAM21032.1 - 0.17 11.5 2.9 7.8 6.2 0.1 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain bZIP_1 PF00170.16 GAM21032.1 - 0.26 11.2 9.4 2.3 8.2 1.1 3.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4201 PF13870.1 GAM21032.1 - 0.84 9.0 25.2 0.7 9.2 1.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) DUF724 PF05266.9 GAM21032.1 - 0.94 9.0 15.2 0.4 10.2 6.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) M PF02370.11 GAM21032.1 - 3 8.5 8.7 1.7 9.2 1.8 3.0 2 0 0 2 2 2 0 M protein repeat TMF_DNA_bd PF12329.3 GAM21032.1 - 4 7.3 15.7 0.46 10.3 6.3 2.9 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 GAM21032.1 - 5.1 5.4 4.9 9.2 4.5 0.1 2.3 2 1 0 2 2 2 0 Fusaric acid resistance protein family Imm5 PF14423.1 GAM21033.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 Herpes_LMP1 PF05297.6 GAM21033.1 - 3.2 6.5 5.5 3.8 6.3 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TPD PF14811.1 GAM21034.1 - 4.1e-44 149.4 0.0 6.8e-44 148.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif RPW8 PF05659.6 GAM21034.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 SF3b10 PF07189.6 GAM21035.1 - 6.4e-34 115.6 0.1 7.3e-34 115.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TIM PF00121.13 GAM21035.1 - 0.076 12.0 0.0 0.076 12.0 0.0 1.0 1 0 0 1 1 1 0 Triosephosphate isomerase Glyco_hydro_9 PF00759.14 GAM21036.1 - 9.6e-138 459.7 5.7 1.7e-137 458.9 3.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM49 PF09478.5 GAM21036.1 - 1.1e-18 67.0 0.5 1.1e-18 67.0 0.4 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 TFIIA PF03153.8 GAM21036.1 - 0.87 9.4 5.5 1.2 8.9 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dicty_spore_N PF04562.7 GAM21038.1 - 1.5e-14 54.2 23.1 1.5e-14 54.2 16.0 8.1 3 1 8 11 11 11 1 Dictyostelium spore coat protein, N terminus CBM49 PF09478.5 GAM21038.1 - 0.00039 20.4 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 D-aminoacyl_C PF07908.7 GAM21038.1 - 0.00056 19.1 0.1 2.7 7.3 0.0 4.1 5 0 0 5 5 5 2 D-aminoacylase, C-terminal region Dynamin_N PF00350.18 GAM21039.1 - 2.8e-10 40.2 0.0 6.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 GAM21039.1 - 0.0094 16.4 0.0 0.051 14.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 GAM21039.1 - 0.34 10.8 3.1 2.6 7.9 0.0 3.3 3 1 1 4 4 4 0 AAA ATPase domain AAA_23 PF13476.1 GAM21039.1 - 0.45 10.8 4.6 0.24 11.7 0.1 2.6 2 1 0 2 2 2 0 AAA domain IATP PF04568.7 GAM21039.1 - 1.9 8.5 5.0 3.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Hemocyanin_C PF03723.9 GAM21040.1 - 6.3e-41 140.1 0.1 1e-40 139.4 0.1 1.4 1 0 0 1 1 1 1 Hemocyanin, ig-like domain Hemocyanin_M PF00372.14 GAM21040.1 - 2e-37 128.9 0.0 4.2e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Hemocyanin, copper containing domain Tyrosinase PF00264.15 GAM21040.1 - 0.00017 21.8 0.3 0.00044 20.4 0.1 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase DnaJ PF00226.26 GAM21041.1 - 5.1e-16 58.1 0.5 1.5e-15 56.6 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Host_attach PF10116.4 GAM21041.1 - 0.083 13.1 0.8 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells DnaJ PF00226.26 GAM21042.1 - 2.2e-15 56.1 0.1 5.8e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Vps52 PF04129.7 GAM21043.1 - 2.3e-89 300.2 20.4 4.9e-89 299.1 14.1 1.5 1 1 0 1 1 1 1 Vps52 / Sac2 family AF0941-like PF14591.1 GAM21043.1 - 6.9 6.7 9.8 3.3 7.7 0.3 4.1 4 1 0 4 4 4 0 AF0941-like Metallophos_C PF14008.1 GAM21044.1 - 4.9e-18 64.9 0.2 1.5e-17 63.4 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAM21044.1 - 1.6e-14 53.7 1.7 2.4e-14 53.2 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 GAM21044.1 - 1e-08 34.2 0.2 7.9e-08 31.2 0.1 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAM21044.1 - 7.6e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rhomboid PF01694.17 GAM21045.1 - 7.1e-36 123.4 10.8 7.1e-36 123.4 7.5 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1129 PF06570.6 GAM21045.1 - 0.068 12.4 5.5 5.5 6.2 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) RDD PF06271.7 GAM21045.1 - 0.39 10.6 0.0 0.39 10.6 0.0 3.2 2 1 1 3 3 3 0 RDD family dUTPase PF00692.14 GAM21046.1 - 1.2e-09 37.7 0.0 2.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 dUTPase LAGLIDADG_3 PF14528.1 GAM21046.1 - 0.0009 19.4 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 LAGLIDADG-like domain DnaJ PF00226.26 GAM21047.1 - 1e-22 79.6 3.2 1.7e-22 78.8 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAM21047.1 - 9.6e-13 47.8 0.1 2.9e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAM21047.1 - 1.8e-08 34.3 10.8 6e-08 32.6 7.5 2.0 1 1 0 1 1 1 1 DnaJ central domain Trypan_PARP PF05887.6 GAM21047.1 - 0.087 12.6 1.0 0.16 11.8 0.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Abi_HHR PF07815.9 GAM21047.1 - 0.18 11.9 1.3 1.1 9.3 0.4 2.3 2 0 0 2 2 2 0 Abl-interactor HHR PAT1 PF09770.4 GAM21047.1 - 1.4 7.0 17.5 0.12 10.5 8.3 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PLRV_ORF5 PF01690.12 GAM21047.1 - 3.5 6.6 19.3 6.4 5.8 13.4 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HypA PF01155.14 GAM21047.1 - 9.1 6.0 7.9 54 3.5 5.2 2.4 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ECH PF00378.15 GAM21048.1 - 3.3e-38 131.2 0.0 3.7e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AAA_17 PF13207.1 GAM21049.1 - 4.5e-06 27.4 0.0 1.3e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM21049.1 - 0.00077 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM21049.1 - 0.0041 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM21049.1 - 0.0076 16.5 0.3 0.024 14.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM21049.1 - 0.025 14.3 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM21049.1 - 0.028 14.4 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 GAM21049.1 - 0.028 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM21049.1 - 0.044 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAM21049.1 - 0.08 12.0 0.0 0.46 9.5 0.0 2.1 1 1 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 GAM21049.1 - 0.094 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Cytochrom_B558a PF05038.8 GAM21050.1 - 0.077 12.6 11.5 0.26 10.8 1.7 2.6 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF4131 PF13567.1 GAM21050.1 - 1.3 8.3 7.5 4 6.7 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1056 PF06341.6 GAM21050.1 - 2.1 8.4 6.8 2.5 8.2 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1056) DUF3244 PF11589.3 GAM21051.1 - 6.4e-14 51.5 4.2 0.18 11.5 0.0 11.0 13 0 0 13 13 13 5 Domain of unknown function (DUF3244) Cna_B PF05738.8 GAM21051.1 - 4.2e-06 26.4 0.4 0.00079 19.1 0.1 16.6 20 1 0 20 20 20 5 Cna protein B-type domain DUF2012 PF09430.5 GAM21051.1 - 0.0025 17.6 0.0 21 4.9 0.0 5.8 8 0 0 8 8 8 1 Protein of unknown function (DUF2012) DUF1533 PF07550.6 GAM21051.1 - 0.0029 17.5 1.5 4.5 7.3 0.0 5.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1533) Wzt_C PF14524.1 GAM21051.1 - 0.016 14.8 16.5 0.55 9.9 0.0 8.6 12 0 0 12 12 12 0 Wzt C-terminal domain DUF1416 PF07210.7 GAM21051.1 - 0.051 13.1 0.7 0.36 10.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1416) GCC2_GCC3 PF07699.8 GAM21052.1 - 8.2e-11 41.3 68.1 0.00077 18.9 4.3 7.0 1 1 5 6 6 6 5 GCC2 and GCC3 NCD3G PF07562.9 GAM21052.1 - 0.0035 17.0 54.2 0.014 15.1 1.4 6.8 5 1 2 7 7 7 4 Nine Cysteines Domain of family 3 GPCR Vpu PF00558.14 GAM21052.1 - 0.0083 15.6 0.2 0.017 14.6 0.2 1.4 1 0 0 1 1 1 1 Vpu protein FtsX PF02687.16 GAM21052.1 - 0.1 12.3 0.2 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsX-like permease family Mem_trans PF03547.13 GAM21052.1 - 0.13 10.5 1.4 0.35 9.1 1.1 1.6 1 1 0 1 1 1 0 Membrane transport protein Rifin_STEVOR PF02009.11 GAM21052.1 - 0.23 11.0 2.3 0.26 10.8 0.1 2.0 2 0 0 2 2 2 0 Rifin/stevor family Pex14_N PF04695.8 GAM21052.1 - 0.3 11.1 8.2 0.34 10.9 4.8 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VSP PF03302.8 GAM21052.1 - 0.91 8.0 50.2 0.03 12.9 16.5 3.1 2 1 2 4 4 4 0 Giardia variant-specific surface protein Macoilin PF09726.4 GAM21052.1 - 1.4 7.1 11.4 1.9 6.6 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 GAM21052.1 - 2.7 7.3 10.7 4.4 6.6 7.4 1.3 1 0 0 1 1 1 0 Vta1 like TraP PF07296.6 GAM21053.1 - 0.085 11.8 0.1 0.085 11.8 0.1 2.1 2 0 0 2 2 2 0 TraP protein Glyco_hydro_18 PF00704.23 GAM21054.1 - 3.7e-26 92.3 0.1 4.6e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RE_NgoBV PF09564.5 GAM21054.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 NgoBV restriction endonuclease GHL15 PF14885.1 GAM21054.1 - 0.063 13.4 0.1 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 zf-SNAP50_C PF12251.3 GAM21055.1 - 3.3e-58 196.3 5.1 4.4e-58 195.9 3.5 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal PI-PLC-X PF00388.14 GAM21056.1 - 1.2e-57 193.3 0.1 2.2e-57 192.5 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 GAM21056.1 - 1.9e-32 111.7 0.0 8.2e-32 109.6 0.0 2.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 GAM21056.1 - 1.2e-14 53.8 0.0 4.3e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 GAM21056.1 - 1e-09 38.2 0.3 2.8e-09 36.8 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 GAM21056.1 - 0.037 13.6 4.2 0.051 13.1 1.2 2.2 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.1 GAM21056.1 - 1.4 9.1 6.1 1.9 8.6 1.9 2.5 2 0 0 2 2 2 0 EF-hand domain pair EGF_2 PF07974.8 GAM21057.1 - 0.4 10.8 4.7 1.1 9.5 3.3 1.8 1 0 0 1 1 1 0 EGF-like domain DUF3730 PF12530.3 GAM21058.1 - 2.3e-41 142.2 0.8 2.3e-41 142.2 0.6 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF3730) HEAT PF02985.17 GAM21058.1 - 0.13 12.3 14.8 9.7 6.5 0.0 8.3 9 0 0 9 9 9 0 HEAT repeat Ricin_B_lectin PF00652.17 GAM21059.1 - 0.005 16.8 2.5 0.018 15.0 0.5 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain ABC_membrane PF00664.18 GAM21060.1 - 1.2e-51 175.8 26.4 4.8e-29 101.6 8.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM21060.1 - 6.3e-50 169.0 0.0 1.4e-27 96.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM21060.1 - 4.1e-12 46.6 2.6 0.075 12.9 0.0 6.4 4 2 2 6 6 6 3 AAA domain SMC_N PF02463.14 GAM21060.1 - 3.2e-10 39.6 0.4 0.00073 18.8 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM21060.1 - 4e-05 23.0 3.6 0.07 12.6 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM21060.1 - 0.0002 21.7 2.0 0.099 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM21060.1 - 0.0003 20.7 0.1 0.72 9.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 GAM21060.1 - 0.0003 19.9 0.8 0.012 14.7 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM21060.1 - 0.0074 15.7 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 GAM21060.1 - 0.014 14.0 0.6 2.5 6.5 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ArgK PF03308.11 GAM21060.1 - 0.026 13.2 0.6 2 7.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Miro PF08477.8 GAM21060.1 - 0.03 14.7 1.8 3.1 8.3 0.1 2.9 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 GAM21060.1 - 0.062 13.1 1.1 2.6 7.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 GAM21060.1 - 0.28 10.6 0.4 8.1 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 GAM21060.1 - 0.41 10.6 2.1 4 7.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AIG1 PF04548.11 GAM21060.1 - 2.3 7.2 6.3 2.5 7.1 0.1 2.7 3 0 0 3 3 3 0 AIG1 family Dynamin_N PF00350.18 GAM21060.1 - 5.4 6.8 5.8 1.5 8.6 0.4 2.3 2 0 0 2 2 2 0 Dynamin family Pterin_bind PF00809.17 GAM21061.1 - 4.7e-58 196.0 0.0 7.4e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 GAM21061.1 - 3.8e-39 133.3 0.0 6.4e-39 132.5 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 GAM21061.1 - 5.5e-14 52.3 0.0 9.9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Dihydroneopterin aldolase RhoGEF PF00621.15 GAM21062.1 - 1.5e-37 129.2 0.1 1.5e-37 129.2 0.1 2.6 2 1 0 2 2 2 1 RhoGEF domain Arm PF00514.18 GAM21062.1 - 6.9e-14 51.0 13.1 0.0001 21.9 0.1 7.5 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat PH PF00169.24 GAM21062.1 - 4.9e-10 39.5 1.0 1.2e-09 38.2 0.7 1.7 1 0 0 1 1 1 1 PH domain HEAT_2 PF13646.1 GAM21062.1 - 0.0021 18.2 2.5 0.14 12.5 0.0 4.0 4 1 1 5 5 5 1 HEAT repeats Arm_2 PF04826.8 GAM21062.1 - 0.0027 16.8 12.9 0.032 13.3 5.8 2.9 2 0 0 2 2 2 2 Armadillo-like HEAT_EZ PF13513.1 GAM21062.1 - 0.016 15.6 0.6 1.9 9.1 0.0 3.7 3 1 0 3 3 3 0 HEAT-like repeat DUF3766 PF12611.3 GAM21062.1 - 0.051 13.1 0.9 0.12 11.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3766) CTNNBL PF08216.6 GAM21062.1 - 0.2 11.2 8.1 0.99 9.0 0.1 4.0 3 1 1 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear RICTOR_V PF14668.1 GAM21062.1 - 0.21 11.5 2.4 3.8 7.5 0.1 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 GAM21062.1 - 1.4 9.1 3.8 12 6.2 0.1 4.1 5 0 0 5 5 5 0 HEAT repeat ADH_N PF08240.7 GAM21063.1 - 2.8e-30 104.2 6.2 5.5e-30 103.3 4.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM21063.1 - 1e-17 63.8 0.0 1.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM21063.1 - 0.00063 20.6 0.0 0.0013 19.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 GAM21063.1 - 0.0035 17.3 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 GAM21063.1 - 0.0053 15.9 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 GAM21063.1 - 0.029 13.0 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AlaDh_PNT_C PF01262.16 GAM21063.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cortex-I_coil PF09304.5 GAM21064.1 - 3.2e-39 133.2 21.9 3.2e-39 133.2 15.2 2.5 3 0 0 3 3 2 1 Cortexillin I, coiled coil CH PF00307.26 GAM21064.1 - 1.2e-33 115.4 0.0 2.2e-16 59.8 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM21064.1 - 0.00027 20.5 0.0 0.1 12.2 0.0 2.9 2 1 0 2 2 2 1 CAMSAP CH domain Myosin_tail_1 PF01576.14 GAM21064.1 - 0.00071 17.4 23.0 0.00071 17.4 16.0 1.7 2 0 0 2 2 2 1 Myosin tail DUF1217 PF06748.7 GAM21064.1 - 0.0062 16.6 1.1 0.023 14.7 0.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1217) Vps23_core PF09454.5 GAM21064.1 - 0.046 13.3 0.4 2 8.1 0.1 2.6 2 0 0 2 2 2 0 Vps23 core domain GPAT_N PF14829.1 GAM21064.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Reo_sigmaC PF04582.7 GAM21064.1 - 0.11 11.6 2.1 0.2 10.7 1.4 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4239 PF14023.1 GAM21064.1 - 0.31 10.3 1.2 0.49 9.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Macoilin PF09726.4 GAM21064.1 - 0.33 9.1 12.8 0.52 8.5 8.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Baculo_PEP_C PF04513.7 GAM21064.1 - 1.9 8.2 7.4 1.3 8.8 2.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 GAM21064.1 - 1.9 6.2 7.9 3.2 5.5 5.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 GAM21064.1 - 6 6.7 30.4 19 5.1 4.2 4.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 GAM21064.1 - 7.4 6.9 28.9 0.98 9.7 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) FUSC PF04632.7 GAM21064.1 - 8.1 4.7 5.4 11 4.3 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin PF00804.20 GAM21064.1 - 8.6 6.5 14.6 5.3 7.2 8.2 2.1 1 1 1 2 2 2 0 Syntaxin APG6 PF04111.7 GAM21064.1 - 8.8 5.2 23.1 9.6 5.1 13.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 F420_oxidored PF03807.12 GAM21065.1 - 5.5e-08 33.1 0.4 1.1e-07 32.2 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAM21065.1 - 0.0026 17.6 0.4 0.0063 16.3 0.1 1.7 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 GAM21065.1 - 0.0091 15.7 0.2 0.19 11.4 0.1 2.4 1 1 1 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus I_LWEQ PF01608.12 GAM21066.1 - 1.9e-50 170.7 9.4 1.9e-50 170.7 6.5 4.3 3 2 2 5 5 5 2 I/LWEQ domain ANTH PF07651.11 GAM21066.1 - 1.1e-42 145.7 0.4 1.1e-42 145.7 0.3 3.0 3 0 0 3 3 3 1 ANTH domain ENTH PF01417.15 GAM21066.1 - 1.8e-09 37.4 0.2 7.3e-09 35.5 0.1 2.1 1 0 0 1 1 1 1 ENTH domain V_ATPase_I PF01496.14 GAM21066.1 - 0.17 9.6 6.1 0.4 8.4 4.2 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4298 PF14131.1 GAM21066.1 - 0.38 10.6 8.8 0.76 9.6 1.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) IncA PF04156.9 GAM21066.1 - 1.4 8.4 18.7 0.012 15.1 3.7 3.2 3 0 0 3 3 3 0 IncA protein PX PF00787.19 GAM21067.1 - 2e-15 56.5 1.2 3.3e-15 55.8 0.3 1.8 2 0 0 2 2 2 1 PX domain DUF2002 PF09400.5 GAM21067.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) LIM PF00412.17 GAM21068.1 - 1.4e-26 92.2 34.9 8.4e-11 41.7 1.7 4.1 3 1 0 4 4 4 3 LIM domain zf-DNA_Pol PF08996.5 GAM21068.1 - 0.017 14.5 2.0 0.017 14.5 1.4 3.3 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger BSP_II PF05432.6 GAM21069.1 - 0.43 9.7 25.9 1.1 8.4 18.0 1.7 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) EF-hand_5 PF13202.1 GAM21070.1 - 0.05 12.9 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 EF hand CbiJ PF02571.9 GAM21070.1 - 0.086 12.1 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK EF-hand_7 PF13499.1 GAM21071.1 - 9.2e-16 57.7 4.1 1.8e-15 56.7 0.9 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM21071.1 - 0.00066 19.3 1.2 0.79 9.7 0.1 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 GAM21071.1 - 0.0013 17.9 3.0 0.14 11.4 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 GAM21071.1 - 0.0013 17.9 0.1 0.0084 15.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 GAM21071.1 - 0.024 14.2 2.8 0.11 12.1 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain pair Epimerase PF01370.16 GAM21071.1 - 0.13 11.6 0.5 0.27 10.6 0.4 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Exo_endo_phos PF03372.18 GAM21072.1 - 3.6e-22 79.5 0.0 1.3e-21 77.6 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAM21072.1 - 1e-08 34.8 0.6 6.2e-08 32.2 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Menin PF05053.8 GAM21072.1 - 0.049 11.8 2.4 0.06 11.5 1.7 1.1 1 0 0 1 1 1 0 Menin Tim54 PF11711.3 GAM21072.1 - 0.13 10.8 2.2 0.16 10.5 1.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Choline_kinase PF01633.15 GAM21073.1 - 4.2e-60 202.9 0.2 4.2e-60 202.9 0.2 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 GAM21073.1 - 4.8e-09 36.3 0.0 7.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 GAM21073.1 - 6.5e-05 22.2 2.1 0.00045 19.4 0.3 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 GAM21073.1 - 0.00074 18.2 1.4 0.0012 17.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Tim17 PF02466.14 GAM21074.1 - 4.5e-06 26.7 1.8 6.7e-06 26.1 1.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3087 PF11286.3 GAM21074.1 - 0.06 12.5 0.1 0.091 11.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) DUF4538 PF15061.1 GAM21074.1 - 0.087 12.1 0.3 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF2104 PF09877.4 GAM21074.1 - 0.12 12.3 0.2 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) NinG PF05766.7 GAM21074.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein NUDIX_2 PF13869.1 GAM21075.1 - 1.1e-79 266.2 0.0 1.2e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 GAM21075.1 - 0.0019 17.8 0.0 0.0033 17.0 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Snf7 PF03357.16 GAM21077.1 - 1.4e-30 105.9 19.6 1.7e-30 105.6 13.6 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 GAM21077.1 - 1.7 8.6 11.4 0.3 11.1 4.3 2.0 1 1 1 2 2 2 0 YlqD protein tRNA_int_end_N2 PF12928.2 GAM21078.1 - 6.6e-13 47.9 0.0 1.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 GAM21078.1 - 6.6e-05 22.3 0.1 0.00012 21.5 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain DUF663 PF04950.7 GAM21078.1 - 0.017 14.0 0.8 0.026 13.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF663) HABP4_PAI-RBP1 PF04774.10 GAM21078.1 - 0.084 13.3 6.6 0.18 12.3 4.6 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DUF521 PF04412.8 GAM21078.1 - 0.1 11.1 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Ded_cyto PF06920.8 GAM21079.1 - 6.4e-46 155.8 0.1 1.3e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM21079.1 - 4e-25 88.5 0.6 4e-25 88.5 0.4 2.0 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.12 GAM21079.1 - 9e-05 21.8 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Myotub-related PF06602.9 GAM21082.1 - 2.9e-07 29.5 11.7 5.8e-05 22.0 0.0 3.8 4 0 0 4 4 4 3 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAM21082.1 - 4.5e-06 27.0 0.1 0.01 16.1 0.0 3.6 3 0 0 3 3 3 2 Tyrosine phosphatase family WH1 PF00568.18 GAM21083.1 - 5.3e-20 71.2 0.2 7.4e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 GAM21083.1 - 2e-16 60.1 0.2 4.2e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 GAM21083.1 - 4.7e-08 32.3 0.2 1.1e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 WH2 motif DUF2360 PF10152.4 GAM21083.1 - 0.12 12.6 1.7 1.9 8.7 0.6 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DCP1 PF06058.8 GAM21083.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family DDRGK PF09756.4 GAM21085.1 - 4.9e-59 198.9 35.7 4.9e-59 198.9 24.8 2.1 2 0 0 2 2 2 2 DDRGK domain B-block_TFIIIC PF04182.7 GAM21085.1 - 0.017 14.9 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Med3 PF11593.3 GAM21085.1 - 6.2 5.9 14.6 11 5.1 10.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ATP11 PF06644.6 GAM21085.1 - 8.9 5.7 20.4 12 5.3 11.0 2.2 2 0 0 2 2 2 0 ATP11 protein AAA PF00004.24 GAM21087.1 - 5.1e-43 146.4 0.0 1.1e-42 145.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM21087.1 - 4.1e-07 29.8 0.0 7.2e-06 25.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM21087.1 - 5.4e-07 29.7 0.0 1.2e-05 25.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM21087.1 - 1.7e-06 28.1 0.1 0.00097 19.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 GAM21087.1 - 2.7e-06 26.5 0.0 5.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 GAM21087.1 - 1.6e-05 24.9 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 GAM21087.1 - 0.00013 22.7 0.6 0.00036 21.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAM21087.1 - 0.0003 20.4 0.0 0.0007 19.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 GAM21087.1 - 0.00034 20.0 0.3 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 GAM21087.1 - 0.00072 19.8 0.1 0.0025 18.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM21087.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM21087.1 - 0.0012 19.0 0.0 0.0044 17.1 0.0 2.0 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 GAM21087.1 - 0.0016 17.2 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 GAM21087.1 - 0.0019 17.1 0.1 0.0049 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 GAM21087.1 - 0.0031 16.7 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAM21087.1 - 0.0034 17.2 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 GAM21087.1 - 0.0035 17.1 0.0 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 GAM21087.1 - 0.0052 16.2 0.1 0.026 13.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 GAM21087.1 - 0.0055 16.3 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM21087.1 - 0.006 16.0 0.0 0.022 14.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 GAM21087.1 - 0.008 15.9 0.3 0.047 13.3 0.0 2.3 2 1 0 2 2 2 1 Archaeal ATPase UPF0079 PF02367.12 GAM21087.1 - 0.0095 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 GAM21087.1 - 0.01 14.9 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 GAM21087.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 GAM21087.1 - 0.016 14.9 0.0 0.049 13.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.1 GAM21087.1 - 0.021 14.4 0.3 0.041 13.4 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 GAM21087.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 GAM21087.1 - 0.03 14.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 GAM21087.1 - 0.042 13.0 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 GAM21087.1 - 0.047 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 GAM21087.1 - 0.047 12.8 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 KaiC YkuI_C PF10388.4 GAM21087.1 - 0.059 13.0 0.8 0.13 11.9 0.6 1.5 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain AAA_11 PF13086.1 GAM21087.1 - 0.075 12.5 0.7 0.25 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAM21087.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1043 PF06295.7 GAM21087.1 - 0.31 10.6 2.3 0.61 9.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF59 PF01883.14 GAM21088.1 - 5.2e-10 39.1 0.0 9.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 DUF3068 PF11271.3 GAM21089.1 - 0.047 12.7 0.1 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Tropomyosin_1 PF12718.2 GAM21090.1 - 0.0039 17.0 39.9 0.0039 17.0 27.7 2.6 3 1 1 4 4 4 1 Tropomyosin like DUF4557 PF15101.1 GAM21090.1 - 0.0067 16.2 8.3 0.0067 16.2 5.8 3.4 1 1 2 3 3 3 1 Domain of unknown function (DUF4557) Sec8_exocyst PF04048.9 GAM21090.1 - 0.014 15.0 27.7 0.018 14.6 9.2 3.3 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain FUSC PF04632.7 GAM21090.1 - 0.015 13.7 5.4 0.023 13.1 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cas_Csa4 PF09703.5 GAM21090.1 - 2.2 7.1 9.4 0.44 9.4 4.0 1.6 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) CENP-F_leu_zip PF10473.4 GAM21090.1 - 9.7 6.0 49.8 0.18 11.6 14.2 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRR_4 PF12799.2 GAM21091.1 - 3e-52 173.5 71.0 1.6e-10 40.3 3.4 10.7 6 3 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM21091.1 - 2.7e-39 132.7 54.9 6.7e-11 41.7 0.7 8.1 4 2 5 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 GAM21091.1 - 9.2e-39 125.4 48.0 0.004 16.9 0.1 16.4 17 0 0 17 17 17 14 Leucine Rich Repeat LRR_7 PF13504.1 GAM21091.1 - 2.2e-25 84.2 46.2 0.026 14.6 0.1 16.6 17 0 0 17 17 17 9 Leucine rich repeat LRR_6 PF13516.1 GAM21091.1 - 1.2e-09 37.2 56.0 0.055 13.5 0.3 14.5 15 2 1 16 16 16 7 Leucine Rich repeat SnoaL_2 PF12680.2 GAM21093.1 - 0.0045 17.3 0.0 0.0053 17.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 GAM21093.1 - 0.013 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Nucleoplasmin PF03066.10 GAM21094.1 - 0.021 14.3 14.4 0.019 14.4 10.0 1.1 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 GAM21094.1 - 0.29 10.9 7.7 0.3 10.8 5.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Voldacs PF03517.8 GAM21094.1 - 0.35 10.7 5.6 0.32 10.8 3.9 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling PPP4R2 PF09184.6 GAM21094.1 - 0.56 9.6 9.3 0.5 9.8 6.4 1.2 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 GAM21094.1 - 0.59 8.0 7.2 0.62 8.0 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 GAM21094.1 - 0.71 8.5 17.2 0.64 8.6 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol3_a_NII PF11490.3 GAM21094.1 - 0.89 9.1 4.6 1.1 8.8 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Sigma70_ner PF04546.8 GAM21094.1 - 0.99 8.9 11.8 1 8.9 8.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop53 PF07767.6 GAM21094.1 - 1.2 8.0 6.0 1.2 8.0 4.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sporozoite_P67 PF05642.6 GAM21094.1 - 1.3 6.8 10.0 1.5 6.6 6.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.7 GAM21094.1 - 1.4 8.6 11.3 1.3 8.6 7.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CobT PF06213.7 GAM21094.1 - 1.5 7.8 10.0 1.3 8.1 6.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 GAM21094.1 - 2.4 6.5 12.0 2.1 6.7 8.3 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 GAM21094.1 - 3.7 6.7 12.3 3.3 6.9 8.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 GAM21094.1 - 3.8 5.3 13.8 3.3 5.5 9.6 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 GAM21094.1 - 6.4 5.6 7.3 5.7 5.8 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tom22 PF04281.8 GAM21094.1 - 7.3 6.1 8.1 7.1 6.1 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DNA_pol_phi PF04931.8 GAM21094.1 - 8.7 3.9 16.4 7.8 4.1 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.7 GAM21094.1 - 9.9 5.3 12.9 9.2 5.4 8.9 1.1 1 0 0 1 1 1 0 NOA36 protein bZIP_2 PF07716.10 GAM21095.1 - 3.4e-08 33.1 5.2 3.4e-08 33.1 3.6 4.3 5 0 0 5 5 5 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM21095.1 - 8.7e-07 28.8 4.6 8.7e-07 28.8 3.2 2.8 3 0 0 3 3 3 1 bZIP transcription factor CBM49 PF09478.5 GAM21097.1 - 2.3e-10 40.4 0.1 5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Myco_19_kDa PF05481.7 GAM21097.1 - 1.2 8.9 15.0 0.077 12.8 3.3 2.8 3 1 0 3 3 3 0 Mycobacterium 19 kDa lipoprotein antigen DUF3439 PF11921.3 GAM21097.1 - 5.5 6.7 11.7 5.6 6.7 7.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PARP PF00644.15 GAM21098.1 - 9.8e-69 230.8 0.0 9.8e-69 230.8 0.0 3.5 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAM21098.1 - 4.9e-47 158.9 1.2 1e-46 157.8 0.8 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 GAM21098.1 - 2.7e-23 81.7 1.8 8.2e-23 80.1 1.3 1.9 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 GAM21098.1 - 5.4e-11 42.4 0.0 3.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM21098.1 - 0.00068 19.4 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain Dicty_REP PF05086.7 GAM21098.1 - 8.4 4.0 24.0 14 3.2 15.2 2.0 1 1 1 2 2 2 0 Dictyostelium (Slime Mold) REP protein Kelch_6 PF13964.1 GAM21100.1 - 0.014 15.5 1.1 3 8.1 0.1 3.1 3 0 0 3 3 3 0 Kelch motif V-SNARE PF05008.10 GAM21101.1 - 0.0048 17.0 0.4 0.0048 17.0 0.3 3.9 4 0 0 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Vps51 PF08700.6 GAM21101.1 - 0.049 13.4 0.2 0.049 13.4 0.1 3.8 4 0 0 4 4 4 0 Vps51/Vps67 Gln-synt_C PF00120.19 GAM21101.1 - 0.064 12.4 0.5 0.1 11.7 0.3 1.4 1 1 0 1 1 1 0 Glutamine synthetase, catalytic domain ABC_tran_2 PF12848.2 GAM21101.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.7 3 0 0 3 3 3 0 ABC transporter Aminotran_1_2 PF00155.16 GAM21101.1 - 0.28 10.1 3.2 0.57 9.0 0.1 2.2 2 0 0 2 2 2 0 Aminotransferase class I and II Vpu PF00558.14 GAM21101.1 - 1.6 8.3 5.5 1.1 8.8 1.6 2.5 2 0 0 2 2 2 0 Vpu protein NAD_binding_6 PF08030.7 GAM21101.1 - 6.5 6.6 9.7 79 3.1 6.7 2.3 1 1 0 1 1 1 0 Ferric reductase NAD binding domain HCaRG PF07258.9 GAM21102.1 - 1e-22 80.5 10.0 1.3e-22 80.1 6.9 1.1 1 0 0 1 1 1 1 HCaRG protein RRM_5 PF13893.1 GAM21103.1 - 2.6e-14 52.7 0.3 2.3e-09 36.9 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM21103.1 - 2.5e-13 49.4 1.5 1.5e-10 40.5 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21103.1 - 1.1e-11 44.5 0.1 2.6e-09 36.8 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) COG2 PF06148.6 GAM21103.1 - 0.82 9.5 11.9 0.16 11.8 0.7 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 GAM21103.1 - 0.82 9.4 10.7 2.1 8.1 0.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 GAM21103.1 - 3.7 8.3 8.1 0.52 11.0 0.3 3.3 2 1 1 3 3 3 0 Occludin homology domain Pkinase PF00069.20 GAM21104.1 - 1.3e-70 237.5 0.0 2.3e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21104.1 - 4.7e-51 173.3 0.0 7.5e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM21104.1 - 0.0005 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RecT PF03837.9 GAM21104.1 - 2.1 7.5 10.4 1.8 7.8 3.4 2.4 1 1 1 2 2 2 0 RecT family DUF1057 PF06342.7 GAM21105.1 - 0.053 12.3 1.6 0.096 11.4 1.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Alpha-mann_mid PF09261.6 GAM21105.1 - 2.1 8.6 6.4 0.24 11.6 0.1 2.5 2 0 0 2 2 2 0 Alpha mannosidase, middle domain Macoilin PF09726.4 GAM21105.1 - 7.1 4.7 48.0 0.76 7.9 16.4 2.0 1 1 1 2 2 2 0 Transmembrane protein TBP PF00352.16 GAM21107.1 - 5.4e-63 208.3 0.9 7.9e-34 114.8 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 GAM21107.1 - 3e-05 24.0 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.1 GAM21107.1 - 0.069 12.7 0.1 0.19 11.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Cmc1 PF08583.5 GAM21108.1 - 1.7e-15 56.4 8.2 2.6e-15 55.9 5.6 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 GAM21108.1 - 0.026 14.4 1.8 0.045 13.6 1.3 1.4 1 0 0 1 1 1 0 CHCH domain DUF3128 PF11326.3 GAM21108.1 - 0.54 10.4 4.4 0.32 11.1 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Ribosomal_S24e PF01282.14 GAM21109.1 - 2.7e-29 100.7 0.5 6.1e-29 99.6 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S24e GST_C PF00043.20 GAM21110.1 - 1.5e-12 47.3 0.1 2.9e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM21110.1 - 7.7e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM21110.1 - 8.9e-10 38.6 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM21110.1 - 6.2e-08 32.5 0.0 1.6e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM21110.1 - 3.8e-06 26.6 0.2 1.5e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM21110.1 - 1.1e-05 25.8 0.2 1.9e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 5_nucleotid PF05761.9 GAM21111.1 - 4.4e-136 453.9 3.2 5.2e-136 453.7 2.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family DUF3246 PF11596.3 GAM21111.1 - 0.013 14.8 6.9 0.021 14.0 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Serglycin PF04360.7 GAM21111.1 - 5.6 6.6 18.5 17 5.1 12.8 1.7 1 1 0 1 1 1 0 Serglycin Gelsolin PF00626.17 GAM21112.1 - 3.1e-40 135.7 0.1 2.4e-12 46.3 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat SMC_N PF02463.14 GAM21113.1 - 6.6e-40 136.6 50.5 8.3e-39 133.0 35.0 3.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM21113.1 - 7.2e-27 93.7 0.0 3.3e-26 91.5 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 GAM21113.1 - 4.8e-15 56.4 0.3 4.8e-15 56.4 0.2 6.7 2 2 2 5 5 5 1 AAA domain AAA_21 PF13304.1 GAM21113.1 - 4.5e-11 43.2 8.1 1.1e-06 28.8 0.3 3.5 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM21113.1 - 9.3e-06 25.0 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM21113.1 - 0.016 15.4 0.0 0.016 15.4 0.0 6.0 4 2 0 4 4 4 0 ABC transporter AAA_22 PF13401.1 GAM21113.1 - 1.7 8.7 7.9 8.7 6.4 0.0 4.4 4 2 2 6 6 6 0 AAA domain Peptidase_C1 PF00112.18 GAM21114.1 - 1.1e-47 162.7 3.7 1.1e-47 162.7 2.6 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 GAM21114.1 - 7.6e-06 24.7 0.6 0.00038 19.1 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Ependymin PF00811.13 GAM21115.1 - 1.6e-06 27.8 0.6 3e-06 26.9 0.4 1.6 1 1 0 1 1 1 1 Ependymin DUF4209 PF13910.1 GAM21116.1 - 2.5e-20 72.3 0.0 6.4e-19 67.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4209) TRAM_LAG1_CLN8 PF03798.11 GAM21117.1 - 5.1e-20 71.8 11.4 5.1e-20 71.8 7.9 1.5 2 0 0 2 2 2 1 TLC domain DUF3446 PF11928.3 GAM21117.1 - 0.012 15.7 2.7 0.19 11.9 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SieB PF14163.1 GAM21117.1 - 0.26 10.8 5.0 3.6 7.1 0.7 2.4 2 0 0 2 2 2 0 Superinfection exclusion protein B FNIP PF05725.7 GAM21118.1 - 1.7e-88 290.3 31.0 7.5e-15 54.6 0.3 10.4 8 2 1 11 11 11 9 FNIP Repeat DUF1769 PF08588.5 GAM21118.1 - 0.04 13.8 10.3 4.8 7.2 0.0 6.4 4 3 4 8 8 8 0 Protein of unknown function (DUF1769) Peptidase_M20 PF01546.23 GAM21119.1 - 8.1e-23 80.9 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM21119.1 - 7.5e-15 54.6 0.0 2.4e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain PigN PF04987.9 GAM21120.1 - 3.7e-72 243.3 23.7 5.2e-72 242.8 16.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 GAM21120.1 - 1.2e-15 57.7 0.1 1.5e-08 34.4 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM21120.1 - 1.3e-06 27.8 0.6 3.2e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 GAM21120.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Tic20 PF09685.5 GAM21120.1 - 0.0073 16.2 2.1 0.0073 16.2 1.4 3.9 3 1 0 3 3 3 1 Tic20-like protein EphA2_TM PF14575.1 GAM21120.1 - 0.12 12.8 0.0 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1129 PF06570.6 GAM21120.1 - 0.46 9.7 10.7 0.06 12.6 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Pkinase PF00069.20 GAM21121.1 - 1.9e-47 161.5 1.3 3.8e-36 124.5 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21121.1 - 4.5e-32 111.1 0.4 1.8e-24 86.1 0.1 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM21121.1 - 0.0003 19.8 0.0 0.0015 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RRN3 PF05327.6 GAM21121.1 - 4.9 5.1 19.8 0.95 7.4 6.8 2.6 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 GAM21121.1 - 8.1 4.3 16.6 2.4 6.0 6.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Myb_Cef PF11831.3 GAM21122.1 - 2.2e-34 118.6 8.1 2.2e-34 118.6 5.6 3.8 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 GAM21122.1 - 4.6e-21 74.5 4.2 1e-09 38.2 0.2 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM21122.1 - 2.4e-17 62.7 4.4 4.8e-13 48.9 2.6 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF221 PF02714.10 GAM21123.1 - 3.8e-10 39.1 27.4 3.8e-10 39.1 19.0 2.8 3 2 0 3 3 3 1 Domain of unknown function DUF221 Glyco_hydro_25 PF01183.15 GAM21124.1 - 6.1e-11 42.4 0.1 6.8e-11 42.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Peptidase_S24 PF00717.18 GAM21125.1 - 5.7e-08 32.2 0.1 8.7e-08 31.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DDT PF02791.12 GAM21125.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 DDT domain GATA PF00320.22 GAM21126.1 - 2.6e-15 55.4 3.8 8e-15 53.9 2.7 1.9 1 0 0 1 1 1 1 GATA zinc finger NinG PF05766.7 GAM21126.1 - 0.06 13.0 6.1 0.1 12.3 4.2 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Cytochrom_c3_2 PF14537.1 GAM21126.1 - 1.1 9.6 10.5 0.088 13.1 3.0 2.4 2 0 0 2 2 2 0 Cytochrome c3 TIG PF01833.19 GAM21127.1 - 2.9e-20 72.0 59.6 7.5e-05 22.6 3.4 9.9 8 2 2 10 10 10 6 IPT/TIG domain hEGF PF12661.2 GAM21127.1 - 0.011 15.7 4.1 0.027 14.5 2.8 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF gag-asp_proteas PF13975.1 GAM21127.1 - 0.025 14.3 0.7 2.3 8.1 0.1 2.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease EGF_2 PF07974.8 GAM21127.1 - 2.2 8.4 20.4 0.041 14.0 8.7 2.1 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.22 GAM21127.1 - 4.9 7.2 11.3 0.54 10.2 4.5 1.9 2 0 0 2 2 2 0 EGF-like domain DnaJ-X PF14308.1 GAM21129.1 - 0.036 13.3 5.7 0.044 13.0 3.9 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing TPR_MLP1_2 PF07926.7 GAM21129.1 - 0.041 13.6 8.7 0.047 13.4 6.0 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2868 PF11067.3 GAM21129.1 - 0.21 10.6 0.9 0.22 10.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Siah-Interact_N PF09032.6 GAM21129.1 - 0.28 11.2 5.9 0.46 10.5 4.1 1.5 1 0 0 1 1 1 0 Siah interacting protein, N terminal DUF4363 PF14276.1 GAM21129.1 - 0.31 10.7 2.9 0.44 10.2 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) EMP70 PF02990.11 GAM21130.1 - 4.8e-194 645.6 10.5 6.3e-194 645.2 7.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 RELT PF12606.3 GAM21130.1 - 1.2 8.3 0.0 1.2 8.3 0.0 3.8 4 0 0 4 4 4 0 Tumour necrosis factor receptor superfamily member 19 RRM_1 PF00076.17 GAM21131.1 - 1e-23 82.7 0.5 2e-11 43.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21131.1 - 2.8e-15 55.9 0.3 1.3e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21131.1 - 1.5e-10 40.8 0.3 8.5e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM21131.1 - 0.0017 18.0 0.1 0.0017 18.0 0.0 2.4 3 0 0 3 3 3 1 Limkain b1 DUF2573 PF10835.3 GAM21131.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) DUF3362 PF11842.3 GAM21131.1 - 0.12 12.2 4.6 0.037 13.9 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3362) TMEM237 PF15383.1 GAM21131.1 - 6 5.9 9.7 0.81 8.7 3.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 237 RNase_T PF00929.19 GAM21132.1 - 1.6e-25 90.3 1.9 3.2e-25 89.3 0.3 2.3 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 GAM21132.1 - 0.0095 15.4 0.0 0.032 13.7 0.0 1.9 1 0 0 1 1 1 1 3'-5' exonuclease Annexin PF00191.15 GAM21132.1 - 0.39 10.6 5.0 0.15 11.9 0.3 2.7 3 0 0 3 3 3 0 Annexin DUF2387 PF09526.5 GAM21132.1 - 1.2 9.0 4.3 0.33 10.9 0.2 2.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) MFS_1 PF07690.11 GAM21133.1 - 2.2e-15 56.2 36.8 1e-12 47.4 3.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM21133.1 - 1.5e-09 36.7 28.6 3.6e-07 28.9 6.5 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein Fun_ATP-synt_8 PF05933.8 GAM21133.1 - 0.93 9.5 5.4 20 5.3 1.2 3.4 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) zf-C3HC4_2 PF13923.1 GAM21134.1 - 7.9e-05 22.6 0.4 0.00012 21.9 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ApoL PF05461.6 GAM21134.1 - 8.9e-05 21.8 4.9 0.00013 21.3 3.4 1.4 1 0 0 1 1 1 1 Apolipoprotein L zf-RING_2 PF13639.1 GAM21134.1 - 0.0087 15.8 0.2 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Ring finger domain Cpn60_TCP1 PF00118.19 GAM21135.1 - 3.1e-154 514.2 11.9 3.5e-154 514.0 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MA3 PF02847.12 GAM21135.1 - 0.074 12.7 1.2 15 5.2 0.0 3.2 2 1 1 3 3 3 0 MA3 domain RhoGAP PF00620.22 GAM21136.1 - 2.7e-45 153.7 0.2 5.8e-45 152.6 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 GAM21136.1 - 1.3e-25 89.9 7.6 1.5e-20 73.6 0.5 3.1 2 1 1 3 3 3 2 Divergent CRAL/TRIO domain IPK PF03770.11 GAM21137.1 - 2.6e-43 147.9 0.1 2.6e-43 147.9 0.1 1.3 2 0 0 2 2 2 1 Inositol polyphosphate kinase LMF1 PF06762.9 GAM21138.1 - 4.3e-48 164.0 0.7 2.4e-47 161.6 0.5 1.8 1 1 0 1 1 1 1 Lipase maturation factor PHP PF02811.14 GAM21139.1 - 5.7e-11 42.5 0.0 7.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 PHP domain LRR_6 PF13516.1 GAM21140.1 - 4.6e-07 29.2 18.0 0.37 11.0 0.0 8.8 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 GAM21140.1 - 0.0015 18.1 14.3 0.65 9.6 0.7 6.0 5 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM21140.1 - 0.0026 17.5 24.8 1.7 8.9 1.0 7.9 8 2 0 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM21140.1 - 0.29 11.4 14.4 18 6.0 0.1 6.7 7 1 1 8 8 8 0 Leucine rich repeat Mannitol_dh_C PF08125.8 GAM21141.1 - 1.9e-69 233.5 0.0 2.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 GAM21141.1 - 1e-22 80.7 0.7 2.9e-22 79.2 0.5 1.8 1 1 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain AAA PF00004.24 GAM21142.1 - 5.2e-12 46.0 0.5 4.1e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAM21142.1 - 9.9e-10 37.6 4.5 7.7e-05 21.5 0.0 3.5 3 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 GAM21142.1 - 1.4e-06 28.2 0.0 8.4e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 GAM21142.1 - 1.1e-05 25.5 0.1 0.00014 22.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 GAM21142.1 - 4.3e-05 23.0 0.1 0.00015 21.3 0.1 1.9 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 GAM21142.1 - 7.5e-05 21.8 0.0 0.00018 20.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAM21142.1 - 7.5e-05 23.5 0.4 0.00053 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM21142.1 - 0.00016 21.3 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 GAM21142.1 - 0.00036 20.8 0.0 0.0013 19.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM21142.1 - 0.0022 17.9 0.7 0.0047 16.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 GAM21142.1 - 0.006 16.0 0.1 0.048 13.0 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 GAM21142.1 - 0.0093 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 GAM21142.1 - 0.012 15.9 2.5 0.3 11.3 0.0 3.8 4 0 0 4 4 4 0 ABC transporter KaiC PF06745.8 GAM21142.1 - 0.014 14.5 2.5 0.046 12.8 0.1 2.7 2 1 1 3 3 3 0 KaiC NTPase_1 PF03266.10 GAM21142.1 - 0.026 14.2 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 GAM21142.1 - 0.032 14.4 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 GAM21142.1 - 0.037 13.4 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM21142.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM21142.1 - 0.043 13.7 0.9 0.32 10.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 GAM21142.1 - 0.056 13.3 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAM21142.1 - 0.32 9.8 0.0 0.32 9.8 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein AflR PF08493.5 GAM21142.1 - 0.72 8.8 8.1 1.6 7.7 5.6 1.5 1 0 0 1 1 1 0 Aflatoxin regulatory protein VPS9 PF02204.13 GAM21145.1 - 2.5e-23 82.0 0.3 7.6e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.14 GAM21145.1 - 5e-22 78.5 0.1 2.5e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CTV_P33 PF07184.6 GAM21145.1 - 0.077 11.8 0.4 0.15 10.9 0.3 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein WRKY PF03106.10 GAM21146.1 - 8.5e-38 128.0 21.1 3e-21 75.0 5.8 2.3 2 0 0 2 2 2 2 WRKY DNA -binding domain PBP1_TM PF14812.1 GAM21147.1 - 0.011 16.0 0.1 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BssC_TutF PF08201.6 GAM21147.1 - 0.087 12.3 3.6 0.11 11.9 2.1 1.5 1 1 1 2 2 2 0 BssC/TutF protein Pkinase PF00069.20 GAM21149.1 - 2.8e-48 164.3 5.6 2e-23 82.8 0.0 5.1 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21149.1 - 5e-24 84.7 0.0 6e-13 48.4 0.0 3.9 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 GAM21149.1 - 3.8e-15 55.7 0.0 3.8e-15 55.7 0.0 2.8 3 1 0 3 3 3 1 Histidyl-tRNA synthetase RWD PF05773.17 GAM21149.1 - 2.6e-12 46.6 0.0 1.4e-11 44.2 0.0 2.4 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 GAM21149.1 - 7.4e-11 41.7 0.3 7.4e-11 41.7 0.2 6.5 7 1 1 8 8 8 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.15 GAM21149.1 - 4.1e-07 29.8 0.4 2.6e-06 27.2 0.1 2.5 2 0 0 2 2 2 1 Anticodon binding domain Kinase-like PF14531.1 GAM21149.1 - 4.1e-05 22.6 0.0 0.00026 20.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM21149.1 - 0.12 12.0 0.0 0.77 9.4 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family KH_1 PF00013.24 GAM21150.1 - 8.3e-15 54.1 1.5 1.5e-14 53.3 1.1 1.5 1 0 0 1 1 1 1 KH domain Smr PF01713.16 GAM21150.1 - 1e-10 41.6 0.0 3.7e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 Smr domain KH_3 PF13014.1 GAM21150.1 - 1.5e-09 37.2 0.8 4.1e-09 35.8 0.6 1.8 1 0 0 1 1 1 1 KH domain DUF1771 PF08590.5 GAM21150.1 - 1e-07 31.8 9.5 2.4e-07 30.6 6.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) AAA_11 PF13086.1 GAM21150.1 - 0.024 14.2 4.4 0.037 13.5 3.1 1.3 1 0 0 1 1 1 0 AAA domain KH_2 PF07650.12 GAM21150.1 - 0.063 12.8 1.5 0.12 11.8 0.2 2.0 2 0 0 2 2 2 0 KH domain Myb_CC_LHEQLE PF14379.1 GAM21150.1 - 0.14 11.7 5.7 4.4 6.9 0.9 2.6 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif OmpH PF03938.9 GAM21150.1 - 0.16 11.8 14.9 0.33 10.8 10.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 GAM21150.1 - 0.43 9.5 11.6 0.64 9.0 8.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 GAM21150.1 - 2.1 6.0 5.5 2.7 5.7 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 GAM21150.1 - 3.2 7.2 8.4 5 6.6 5.8 1.3 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 GAM21150.1 - 9.4 5.0 21.8 5.3 5.8 13.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mito_carr PF00153.22 GAM21151.1 - 5e-63 208.8 0.6 1.6e-20 72.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CRAL_TRIO PF00650.15 GAM21152.1 - 4.2e-47 159.5 0.1 6.7e-47 158.9 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAM21152.1 - 3e-14 53.1 0.2 4.5e-14 52.5 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM21152.1 - 1.7e-10 40.8 0.3 5e-10 39.3 0.2 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Peptidase_M50 PF02163.17 GAM21153.1 - 2.6e-15 55.8 0.0 8.1e-14 51.0 0.0 2.4 1 1 0 1 1 1 1 Peptidase family M50 DUF1996 PF09362.5 GAM21154.1 - 1.2e-41 142.9 0.2 1.8e-41 142.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) LRRNT PF01462.13 GAM21154.1 - 0.045 13.2 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain TIG PF01833.19 GAM21155.1 - 5.7e-43 144.8 213.1 1.8e-07 31.0 2.2 18.0 15 3 4 19 19 19 13 IPT/TIG domain EGF_2 PF07974.8 GAM21155.1 - 0.0023 18.0 12.6 0.0054 16.8 8.7 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.22 GAM21155.1 - 0.024 14.5 10.2 0.071 13.1 7.1 1.9 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.2 GAM21155.1 - 0.07 13.2 5.9 0.26 11.4 4.1 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.13 GAM21155.1 - 0.17 11.9 5.0 0.45 10.6 3.5 1.6 1 0 0 1 1 1 0 EB module TIG PF01833.19 GAM21156.1 - 1.7e-49 165.7 157.4 1.5e-06 28.1 1.7 13.3 10 2 3 13 13 13 11 IPT/TIG domain SpoA PF01052.15 GAM21156.1 - 0.034 13.7 0.1 0.45 10.1 0.0 2.6 2 0 0 2 2 2 0 Surface presentation of antigens (SPOA) Aconitase_C PF00694.14 GAM21156.1 - 0.18 11.9 3.4 28 4.8 0.0 4.5 5 0 0 5 5 5 0 Aconitase C-terminal domain TIG PF01833.19 GAM21157.1 - 1.3e-20 73.1 132.7 1.1e-06 28.4 1.4 12.4 8 4 3 11 11 11 8 IPT/TIG domain EGF_2 PF07974.8 GAM21157.1 - 0.0028 17.7 12.5 0.0059 16.7 8.7 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM21157.1 - 0.2 11.8 8.3 0.73 10.0 5.7 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.22 GAM21157.1 - 1.1 9.2 8.8 3 7.8 6.1 1.7 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 GAM21158.1 - 1.5e-70 233.1 256.3 9.3e-07 28.7 3.9 22.2 16 3 7 23 23 23 19 IPT/TIG domain EB PF01683.13 GAM21158.1 - 0.014 15.3 5.0 0.047 13.7 3.4 1.8 1 0 0 1 1 1 0 EB module EGF_2 PF07974.8 GAM21158.1 - 0.036 14.2 12.2 0.081 13.0 8.5 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.2 GAM21158.1 - 0.063 13.3 5.9 0.27 11.3 4.1 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.22 GAM21158.1 - 0.5 10.3 8.7 1.3 9.0 6.1 1.7 1 0 0 1 1 1 0 EGF-like domain FAA_hydrolase PF01557.13 GAM21161.1 - 1.1e-59 201.5 0.0 1.3e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 GAM21161.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 KH domain SRP54 PF00448.17 GAM21162.1 - 6.6e-77 257.4 1.1 1.2e-76 256.5 0.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 GAM21162.1 - 1.6e-23 82.9 1.5 1.6e-23 82.9 1.1 4.6 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 GAM21162.1 - 2.4e-11 43.5 2.3 6.4e-11 42.2 1.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 GAM21162.1 - 6.9e-07 28.8 1.0 4.5e-06 26.2 0.7 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 GAM21162.1 - 3.7e-06 26.7 1.5 0.00029 20.5 1.0 2.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAM21162.1 - 2.5e-05 24.1 0.0 5.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 GAM21162.1 - 7.8e-05 21.9 0.2 0.093 11.9 0.1 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit ArgK PF03308.11 GAM21162.1 - 0.00013 20.8 0.3 0.00056 18.7 0.0 2.1 2 1 0 2 2 2 1 ArgK protein CbiA PF01656.18 GAM21162.1 - 0.00045 19.6 0.2 0.0021 17.4 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 GAM21162.1 - 0.00092 19.1 0.1 0.0023 17.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_31 PF13614.1 GAM21162.1 - 0.0011 18.9 0.1 2 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 GAM21162.1 - 0.0014 18.8 0.6 0.015 15.5 0.4 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 GAM21162.1 - 0.002 17.7 0.0 0.0078 15.8 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_16 PF13191.1 GAM21162.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 GAM21162.1 - 0.0029 17.2 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM21162.1 - 0.0054 16.8 0.1 0.017 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAM21162.1 - 0.0092 16.7 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 GAM21162.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.12 GAM21162.1 - 0.016 14.5 0.3 0.051 12.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase DUF2209 PF09974.4 GAM21162.1 - 0.019 15.0 0.2 0.038 14.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Zeta_toxin PF06414.7 GAM21162.1 - 0.031 13.3 0.0 0.063 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.12 GAM21162.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 GAM21162.1 - 0.039 13.8 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 GAM21162.1 - 0.04 13.6 0.0 0.37 10.5 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Arf PF00025.16 GAM21162.1 - 0.075 12.2 0.1 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2523 PF10734.4 GAM21162.1 - 0.4 10.9 2.9 0.81 9.9 1.1 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2523) Repressor_Mnt PF11423.3 GAM21162.1 - 3.1 7.1 5.6 3.6 6.9 0.5 2.4 2 0 0 2 2 2 0 Regulatory protein Mnt Metallophos PF00149.23 GAM21163.1 - 4.1e-46 156.9 0.2 5e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 GAM21164.1 - 5.9e-26 91.3 0.0 9.5e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAM21164.1 - 6.4e-23 81.3 29.1 9.4e-23 80.7 20.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM21164.1 - 4.1e-14 53.2 2.6 4.1e-14 53.2 1.8 3.4 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAM21164.1 - 0.00072 19.9 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 GAM21164.1 - 0.0037 17.1 0.0 0.039 13.8 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAM21164.1 - 0.0056 16.1 0.1 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 GAM21164.1 - 0.0064 15.9 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein SMC_N PF02463.14 GAM21164.1 - 0.0082 15.4 0.1 0.28 10.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF1772 PF08592.6 GAM21164.1 - 0.017 14.8 0.7 0.057 13.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF258 PF03193.11 GAM21164.1 - 0.14 11.3 0.1 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VPS9 PF02204.13 GAM21165.1 - 8.6e-20 70.7 0.0 2.1e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Vps8 PF12816.2 GAM21166.1 - 5.4e-52 175.9 3.6 5.4e-52 175.9 2.5 3.6 4 0 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 GAM21166.1 - 1.4e-12 47.4 14.2 1.5e-07 31.0 0.4 4.2 4 0 0 4 4 4 3 Region in Clathrin and VPS zf-RING_5 PF14634.1 GAM21166.1 - 0.0022 17.7 5.2 0.0042 16.7 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Stathmin PF00836.14 GAM21166.1 - 0.029 14.0 0.1 0.071 12.7 0.1 1.6 1 0 0 1 1 1 0 Stathmin family zf-rbx1 PF12678.2 GAM21166.1 - 0.034 14.2 2.1 0.088 12.9 1.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 GAM21166.1 - 0.04 13.7 5.2 0.091 12.6 3.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 GAM21166.1 - 0.095 12.3 6.8 0.36 10.5 4.6 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM21166.1 - 2.3 7.9 6.0 5.2 6.8 4.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sulfate_transp PF00916.15 GAM21169.1 - 7.1e-67 225.3 9.3 1.3e-66 224.5 6.5 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM21169.1 - 2.3e-29 100.9 2.7 2.3e-29 100.9 1.9 3.0 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM21169.1 - 2.5e-17 62.3 0.3 3.9e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 STAS domain A_deaminase PF00962.17 GAM21170.1 - 1.6e-106 356.0 0.8 3e-106 355.0 0.2 1.7 2 0 0 2 2 2 1 Adenosine/AMP deaminase IF4E PF01652.13 GAM21172.1 - 1.4e-24 86.5 8.6 1.4e-24 86.5 5.9 2.2 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E AAA_11 PF13086.1 GAM21173.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAM21173.1 - 0.038 14.1 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Kelch_6 PF13964.1 GAM21174.1 - 8.1e-06 25.7 13.1 0.024 14.7 0.6 5.9 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.20 GAM21174.1 - 0.0009 18.7 6.1 0.061 12.8 0.2 5.1 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 GAM21174.1 - 0.0035 17.0 17.5 0.26 11.0 0.0 5.5 5 2 1 6 6 6 3 Galactose oxidase, central domain DEAD PF00270.24 GAM21175.1 - 3.8e-19 68.8 0.2 3.9e-17 62.2 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM21175.1 - 3.1e-12 46.1 0.1 7.3e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 GAM21175.1 - 2.6e-05 24.2 0.0 0.00013 22.1 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.1 GAM21175.1 - 0.00032 20.6 0.2 0.00074 19.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.4 GAM21175.1 - 0.0044 16.5 0.0 0.035 13.6 0.0 2.4 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda ALG3 PF05208.8 GAM21177.1 - 5e-136 453.7 24.0 5.9e-136 453.5 16.6 1.0 1 0 0 1 1 1 1 ALG3 protein Mannosyl_trans PF05007.8 GAM21177.1 - 0.007 16.0 1.6 0.007 16.0 1.1 3.4 3 1 0 3 3 3 2 Mannosyltransferase (PIG-M) DUF4637 PF15470.1 GAM21178.1 - 0.086 12.4 0.3 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Guanylate_cyc PF00211.15 GAM21179.1 - 2.1e-28 98.9 0.3 2.1e-28 98.9 0.2 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.19 GAM21179.1 - 2.1e-18 66.3 0.1 7.4e-11 42.0 0.0 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.21 GAM21179.1 - 3.6e-15 55.6 2.1 1.2e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_2 PF07719.12 GAM21179.1 - 0.0084 15.9 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21179.1 - 0.021 14.4 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21179.1 - 0.025 14.2 0.0 0.069 12.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat UPF0302 PF08864.5 GAM21179.1 - 0.096 12.5 0.4 0.47 10.3 0.2 2.3 2 0 0 2 2 2 0 UPF0302 domain LRR_9 PF14580.1 GAM21180.1 - 1.3e-11 44.3 1.6 3.4e-11 42.9 1.1 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 GAM21180.1 - 2.4e-10 39.8 19.3 2.1e-06 27.2 1.3 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM21180.1 - 6.1e-05 22.6 14.0 0.0022 17.6 4.7 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 GAM21180.1 - 0.0002 21.1 16.3 0.11 12.5 0.4 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 GAM21180.1 - 0.0011 18.7 10.7 1.4 9.4 0.2 5.2 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 GAM21180.1 - 0.049 13.6 12.9 5.3 7.4 0.0 4.3 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_2 PF07723.8 GAM21180.1 - 0.1 13.1 1.8 45 4.7 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat FBPase PF00316.15 GAM21180.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase DUF2603 PF10788.4 GAM21180.1 - 0.15 11.8 3.5 0.71 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) FerA PF08165.6 GAM21180.1 - 0.29 10.8 1.8 12 5.5 0.1 3.3 1 1 2 3 3 3 0 FerA (NUC095) domain ABC2_membrane PF01061.19 GAM21181.1 - 4.1e-31 107.8 23.7 6.3e-31 107.1 16.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM21181.1 - 6.5e-26 91.2 0.0 1.2e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM21181.1 - 1.4e-06 28.5 0.4 0.013 15.4 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM21181.1 - 0.0006 19.8 0.1 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 GAM21181.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAM21181.1 - 0.0014 17.7 0.0 0.71 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 GAM21181.1 - 0.0019 17.7 0.1 0.03 13.7 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 GAM21181.1 - 0.0026 16.9 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAM21181.1 - 0.0028 17.5 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_2 PF12679.2 GAM21181.1 - 0.0033 16.3 3.6 0.0033 16.3 2.5 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_18 PF13238.1 GAM21181.1 - 0.005 17.1 0.1 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM21181.1 - 0.0068 15.9 0.2 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM21181.1 - 0.0074 17.0 0.0 0.015 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM21181.1 - 0.012 15.5 0.2 0.022 14.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM21181.1 - 0.015 15.4 0.1 0.076 13.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM21181.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 GAM21181.1 - 0.02 14.3 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 GAM21181.1 - 0.026 13.7 0.1 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.10 GAM21181.1 - 0.045 13.4 0.1 0.87 9.2 0.1 2.2 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 GAM21181.1 - 0.046 13.3 0.1 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 GAM21181.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2791 PF10923.3 GAM21181.1 - 0.074 11.6 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_19 PF13245.1 GAM21181.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 GAM21181.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 GAM21181.1 - 0.15 11.8 0.3 1.9 8.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Miro PF08477.8 GAM21181.1 - 0.16 12.4 0.1 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein EGF_2 PF07974.8 GAM21182.1 - 0.00051 20.1 11.9 0.0011 19.1 8.2 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM21182.1 - 0.045 13.8 1.6 0.12 12.4 1.1 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF UbiA PF01040.13 GAM21183.1 - 0.00057 19.1 7.1 0.16 11.1 0.0 2.1 2 0 0 2 2 2 2 UbiA prenyltransferase family NfeD PF01957.13 GAM21183.1 - 0.034 14.2 0.2 0.034 14.2 0.2 2.2 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding DAP3 PF10236.4 GAM21185.1 - 2.5e-07 29.9 0.0 0.00032 19.7 0.0 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 SAM_1 PF00536.25 GAM21185.1 - 4.8e-05 23.4 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 GAM21185.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Nup54 PF13874.1 GAM21186.1 - 0.0056 16.3 6.2 0.0056 16.3 4.3 2.4 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Peptidase_C5 PF00770.13 GAM21186.1 - 0.021 14.3 0.0 0.08 12.4 0.0 1.9 1 1 0 1 1 1 0 Adenovirus endoprotease NTR2 PF15458.1 GAM21187.1 - 0.04 13.1 8.1 0.054 12.7 5.6 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Exonuc_VII_L PF02601.10 GAM21187.1 - 0.12 11.4 2.4 0.15 11.2 1.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RRN3 PF05327.6 GAM21187.1 - 0.15 10.1 3.6 0.18 9.8 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP70 PF00012.15 GAM21187.1 - 3 5.6 6.6 4 5.2 4.6 1.1 1 0 0 1 1 1 0 Hsp70 protein AAA_22 PF13401.1 GAM21188.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 GAM21188.1 - 0.073 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.7 GAM21188.1 - 0.077 12.6 0.1 3 7.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_16 PF13191.1 GAM21188.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Glyco_transf_41 PF13844.1 GAM21190.1 - 7.9e-51 172.4 0.4 2.4e-25 88.4 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.23 GAM21190.1 - 6.1e-35 117.4 17.5 1.5e-08 33.8 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21190.1 - 5e-33 112.5 16.1 7.9e-13 47.8 2.0 4.4 3 2 2 5 5 5 5 TPR repeat TPR_2 PF07719.12 GAM21190.1 - 5.7e-29 97.6 11.6 3.4e-06 26.5 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21190.1 - 1.2e-27 95.6 24.5 4.7e-10 39.2 0.1 4.7 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21190.1 - 4.1e-23 79.3 9.5 8.2e-06 25.2 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21190.1 - 3e-21 73.8 18.6 0.00024 21.0 0.8 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21190.1 - 5.5e-20 69.5 16.6 0.00019 20.9 0.0 6.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM21190.1 - 2.9e-19 69.2 10.1 1.4e-06 28.8 1.6 4.5 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21190.1 - 2.1e-17 62.0 3.9 0.084 13.5 0.0 5.8 4 1 2 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 GAM21190.1 - 3.8e-12 45.6 19.3 0.022 14.7 0.3 6.8 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAM21190.1 - 3.2e-11 42.9 8.7 0.22 12.0 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21190.1 - 1.5e-09 38.0 11.2 2.5e-05 24.4 1.8 4.3 2 2 3 5 5 5 3 Tetratricopeptide repeat Sel1 PF08238.7 GAM21190.1 - 0.00064 20.2 10.1 32 5.3 0.5 6.1 7 0 0 7 7 5 0 Sel1 repeat RPN7 PF10602.4 GAM21190.1 - 0.00076 18.9 4.6 1.2 8.4 0.3 3.9 1 1 3 4 4 4 1 26S proteasome subunit RPN7 TPR_9 PF13371.1 GAM21190.1 - 0.00081 19.1 6.4 0.26 11.1 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 GAM21190.1 - 0.0013 18.9 3.7 4.4 8.0 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.3 GAM21190.1 - 0.0082 14.9 3.1 0.26 9.9 0.0 3.0 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 EST1_DNA_bind PF10373.4 GAM21190.1 - 1.1 8.4 5.3 6.8 5.8 1.4 3.1 1 1 2 3 3 3 0 Est1 DNA/RNA binding domain FNIP PF05725.7 GAM21192.1 - 4.4e-77 253.8 17.3 4.5e-14 52.1 0.1 9.3 6 2 5 11 11 11 11 FNIP Repeat RRM_6 PF14259.1 GAM21193.1 - 3.7e-06 26.8 0.0 7.5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21193.1 - 5.8e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM21193.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-T PF15511.1 GAM21193.1 - 0.029 13.6 7.0 0.043 13.0 4.8 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T YL1 PF05764.8 GAM21193.1 - 6.5 6.2 30.3 0.024 14.2 12.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein RRN3 PF05327.6 GAM21193.1 - 7.6 4.5 20.0 4.2 5.3 8.2 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 GWT1 PF06423.7 GAM21194.1 - 5.8e-29 100.9 7.6 5.8e-29 100.9 5.3 2.7 3 1 0 3 3 3 1 GWT1 UPF0233 PF06781.7 GAM21194.1 - 0.11 12.1 0.0 0.11 12.1 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0233) G_glu_transpept PF01019.16 GAM21196.1 - 1.9e-138 462.1 0.0 4.6e-85 286.0 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Methyltransf_18 PF12847.2 GAM21197.1 - 2.1e-06 28.2 0.0 3.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 GAM21197.1 - 0.00012 21.1 0.0 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 GAM21197.1 - 0.00017 22.0 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM21197.1 - 0.00028 20.3 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain SAYSvFN PF10260.4 GAM21198.1 - 4.3e-08 32.8 3.2 7.3e-08 32.0 2.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved domain (SAYSvFN) zf-H2C2 PF09337.5 GAM21198.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger DUF2292 PF10055.4 GAM21198.1 - 0.41 10.0 2.7 2.8 7.3 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized small protein (DUF2292) AAA_11 PF13086.1 GAM21199.1 - 6.7e-64 215.6 0.0 1.9e-63 214.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 GAM21199.1 - 1.1e-59 201.2 0.2 3.2e-59 199.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain SEN1_N PF12726.2 GAM21199.1 - 1.9e-19 69.2 5.0 1.9e-19 69.2 1.5 2.3 2 0 0 2 2 2 1 SEN1 N terminal AAA_19 PF13245.1 GAM21199.1 - 7.7e-12 44.7 0.0 5.4e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM21199.1 - 2.5e-10 40.2 0.0 1.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 GAM21199.1 - 1.2e-05 25.2 0.2 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 GAM21199.1 - 3.9e-05 23.2 0.1 0.26 10.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 GAM21199.1 - 0.005 16.9 0.0 0.098 12.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 GAM21199.1 - 0.037 14.2 0.1 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 GAM21199.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 GAM21199.1 - 0.057 12.8 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 GAM21199.1 - 0.063 12.9 0.0 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.9 GAM21199.1 - 0.079 12.6 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM21199.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TPR_11 PF13414.1 GAM21200.1 - 2.4e-07 30.2 0.5 6.2e-07 28.9 0.4 1.6 1 0 0 1 1 1 1 TPR repeat Apc3 PF12895.2 GAM21200.1 - 0.00043 20.3 8.2 0.14 12.3 1.5 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAM21200.1 - 0.0012 19.4 3.8 0.035 14.8 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21200.1 - 0.0044 16.5 0.4 0.0044 16.5 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21200.1 - 0.0098 16.4 0.1 0.025 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21200.1 - 0.02 15.2 0.5 0.058 13.7 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21200.1 - 0.13 12.2 0.3 0.13 12.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21200.1 - 0.85 9.5 4.3 0.87 9.5 1.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21200.1 - 0.95 9.4 3.3 1.2 9.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21200.1 - 0.96 9.3 3.6 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA_edit PF04073.10 GAM21201.1 - 1.1e-05 25.2 0.0 0.00035 20.4 0.0 2.2 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Atx10homo_assoc PF09759.4 GAM21201.1 - 0.099 12.3 0.1 0.36 10.5 0.0 2.0 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Ras PF00071.17 GAM21202.1 - 2.6e-49 166.7 0.0 3.6e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21202.1 - 5.1e-16 59.2 0.0 7.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM21202.1 - 2e-09 36.8 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM21202.1 - 0.00012 21.2 0.0 0.00021 20.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM21202.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Lipase_GDSL_3 PF14606.1 GAM21202.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MMR_HSR1 PF01926.18 GAM21202.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glycos_transf_2 PF00535.21 GAM21203.1 - 1.9e-17 63.4 0.0 4.1e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 GAM21203.1 - 7.4e-05 22.9 0.1 0.00042 20.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 GAM21203.1 - 7.6e-05 21.9 1.1 0.00012 21.2 0.0 1.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 GAM21203.1 - 9.7e-05 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RhoGAP PF00620.22 GAM21204.1 - 1.7e-32 112.1 0.0 3.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RPEL PF02755.10 GAM21204.1 - 0.0049 16.1 0.0 0.012 14.9 0.0 1.7 1 0 0 1 1 1 1 RPEL repeat FtsX PF02687.16 GAM21205.1 - 8.5e-29 99.7 49.4 7e-16 58.0 8.0 4.5 4 1 0 4 4 4 2 FtsX-like permease family FLO_LFY PF01698.11 GAM21205.1 - 0.68 8.7 2.4 1.2 7.9 1.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Evr1_Alr PF04777.8 GAM21206.1 - 7.2e-09 35.4 0.0 3.6e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Erv1 / Alr family HutD PF05962.6 GAM21207.1 - 8.9e-22 77.7 0.0 1.8e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 HutD DUF3446 PF11928.3 GAM21207.1 - 6.2 7.0 8.5 1.9 8.7 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DcpS_C PF11969.3 GAM21208.1 - 1.9e-26 92.5 0.3 2.5e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 GAM21208.1 - 1.6e-13 51.0 0.2 2.4e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 HIT domain MCM PF00493.18 GAM21209.1 - 3.8e-142 472.9 0.8 5.7e-142 472.3 0.5 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM21209.1 - 2.6e-16 60.1 0.2 2.6e-16 60.1 0.1 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM21209.1 - 1.7e-09 37.1 0.0 5.7e-08 32.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM21209.1 - 6.9e-07 29.0 0.0 1.7e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM21209.1 - 9.9e-05 21.9 0.0 0.0015 18.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM21209.1 - 0.003 17.0 0.1 0.021 14.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM2_N PF12619.3 GAM21209.1 - 0.0071 16.3 56.6 0.0071 16.3 39.2 3.1 2 1 0 2 2 2 1 Mini-chromosome maintenance protein 2 RRM_1 PF00076.17 GAM21210.1 - 1.2e-23 82.4 3.8 2.9e-08 33.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21210.1 - 1.6e-16 60.0 0.1 2.3e-07 30.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21210.1 - 1.9e-13 49.9 3.5 0.00025 20.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RasGEF PF00617.14 GAM21211.1 - 9.2e-46 155.9 0.4 2.1e-45 154.7 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain LRR_8 PF13855.1 GAM21211.1 - 1.6e-21 75.8 33.4 7.8e-09 35.1 3.8 6.3 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 GAM21211.1 - 2.1e-15 55.9 48.8 7e-07 28.7 3.8 8.8 7 2 2 10 10 10 5 Leucine Rich repeats (2 copies) RasGEF_N PF00618.15 GAM21211.1 - 1.3e-13 50.8 0.7 7.7e-13 48.4 0.5 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_1 PF00560.28 GAM21211.1 - 0.0022 17.7 47.5 0.27 11.4 0.0 11.9 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_9 PF14580.1 GAM21211.1 - 0.019 14.5 4.8 1.1 8.8 0.2 2.6 2 0 0 2 2 2 0 Leucine-rich repeat LRR_7 PF13504.1 GAM21211.1 - 3.3 8.3 39.6 3.1 8.3 0.0 10.9 11 0 0 11 11 11 0 Leucine rich repeat FAD-oxidase_C PF02913.14 GAM21212.1 - 9.5e-58 195.4 0.0 1.4e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM21212.1 - 2.2e-37 127.6 0.0 4.1e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain KH_1 PF00013.24 GAM21213.1 - 1.9e-05 24.2 1.2 1.9e-05 24.2 0.8 1.9 2 0 0 2 2 2 1 KH domain Aminotran_5 PF00266.14 GAM21215.1 - 6.6e-39 133.7 0.0 1.3e-38 132.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM21215.1 - 0.00013 20.4 0.0 0.00017 20.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 GAM21215.1 - 0.0018 17.4 0.1 0.0047 16.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 GAM21215.1 - 0.0024 16.4 0.2 0.052 11.9 0.0 2.4 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 GAM21215.1 - 0.0056 15.7 0.0 0.013 14.5 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PALP PF00291.20 GAM21215.1 - 0.061 12.5 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme EB PF01683.13 GAM21217.1 - 0.0052 16.8 2.8 0.012 15.6 1.9 1.6 1 0 0 1 1 1 1 EB module EGF_2 PF07974.8 GAM21217.1 - 0.04 14.0 15.2 0.096 12.8 10.5 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM21217.1 - 0.082 12.8 10.5 0.19 11.7 7.3 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.28 GAM21217.1 - 0.17 12.0 3.4 39 4.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat TIG PF01833.19 GAM21217.1 - 0.2 11.6 14.5 0.052 13.5 1.6 3.7 2 1 1 3 3 3 0 IPT/TIG domain DUF3827 PF12877.2 GAM21217.1 - 0.33 9.0 3.8 0.5 8.4 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SKG6 PF08693.5 GAM21217.1 - 2.2 7.6 11.3 4.7 6.6 7.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF717 PF05338.7 GAM21218.1 - 0.11 12.5 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF717) AT_hook PF02178.14 GAM21218.1 - 0.71 9.7 5.9 1.6 8.6 4.1 1.6 1 0 0 1 1 1 0 AT hook motif PT PF04886.7 GAM21218.1 - 0.78 9.1 5.1 2.2 7.6 3.5 1.9 1 1 0 1 1 1 0 PT repeat APG12 PF04110.8 GAM21219.1 - 2.1e-28 98.3 0.1 3.1e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 GAM21219.1 - 5.3e-07 29.5 0.0 7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Peptidase_C13 PF01650.13 GAM21219.1 - 0.045 13.0 0.1 0.12 11.5 0.0 1.7 1 1 1 2 2 2 0 Peptidase C13 family Sec23_BS PF08033.7 GAM21219.1 - 0.11 12.9 0.5 0.17 12.3 0.3 1.3 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain Mucin PF01456.12 GAM21219.1 - 0.16 11.7 7.8 0.21 11.3 5.4 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Spond_N PF06468.8 GAM21219.1 - 0.23 11.1 2.6 13 5.4 0.0 2.0 2 0 0 2 2 2 0 Spondin_N SSP160 PF06933.6 GAM21219.1 - 2.8 5.8 6.5 3.3 5.5 4.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EF1G PF00647.14 GAM21220.1 - 1.8e-40 136.9 0.4 4.6e-40 135.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 GAM21220.1 - 2.9e-14 52.8 0.0 7.2e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM21220.1 - 3.2e-10 40.0 0.0 5.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM21220.1 - 8.8e-10 38.9 0.0 1.9e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM21220.1 - 1.7e-09 37.3 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM21220.1 - 1.4e-07 31.6 0.0 3.6e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM21220.1 - 3.1e-06 27.0 0.0 6.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 GAM21220.1 - 0.47 10.8 9.3 1.4 9.3 6.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein BK_channel_a PF03493.13 GAM21221.1 - 3.9e-19 68.4 0.6 1.5e-18 66.6 0.2 2.3 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 GAM21221.1 - 2e-12 46.7 13.7 2e-12 46.7 9.5 2.2 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 GAM21221.1 - 2.1e-10 40.1 2.9 2.1e-10 40.1 2.0 2.2 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.13 GAM21221.1 - 3.5e-08 33.4 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Pkinase PF00069.20 GAM21222.1 - 1.7e-74 250.2 0.0 2.2e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21222.1 - 1.3e-37 129.3 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 GAM21222.1 - 1.8e-10 40.8 0.0 3.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 GAM21222.1 - 1.7e-07 30.5 0.0 1.2e-06 27.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAM21222.1 - 7.8e-07 28.3 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RasGEF PF00617.14 GAM21223.1 - 3.7e-61 206.1 3.9 3.7e-61 206.1 2.7 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAM21223.1 - 3.4e-25 88.1 1.5 1.8e-24 85.8 0.3 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif LisH PF08513.6 GAM21223.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 LisH Chordopox_A33R PF05966.7 GAM21223.1 - 0.12 11.1 0.5 0.27 9.9 0.3 1.6 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Peptidase_C13 PF01650.13 GAM21224.1 - 4.9e-46 157.0 0.0 7.7e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C13 family SUR7 PF06687.7 GAM21224.1 - 0.02 14.4 0.8 4.2 6.8 0.1 2.2 2 0 0 2 2 2 0 SUR7/PalI family Vps51 PF08700.6 GAM21225.1 - 3.1e-05 23.7 4.1 4.4e-05 23.2 0.4 3.2 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 GAM21225.1 - 0.0025 17.5 8.1 0.0025 17.5 5.6 3.4 3 1 0 3 3 3 1 Exocyst complex component Sec5 Capsule_synth PF05159.9 GAM21225.1 - 0.012 15.1 1.0 0.024 14.1 0.7 1.5 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein CYTH PF01928.16 GAM21226.1 - 1.1e-13 51.2 0.2 1.7e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 CYTH domain DUF4392 PF14336.1 GAM21226.1 - 0.093 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Metallophos_2 PF12850.2 GAM21227.1 - 0.0025 17.6 0.4 0.0083 15.9 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAM21227.1 - 0.0034 16.8 1.8 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase HdeA PF06411.6 GAM21227.1 - 0.01 15.7 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 HdeA/HdeB family Pox_A32 PF04665.7 GAM21227.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_membrane PF00664.18 GAM21228.1 - 1.3e-70 238.0 33.6 4.3e-36 124.7 10.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM21228.1 - 1.3e-51 174.4 0.2 8e-30 103.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM21228.1 - 1.3e-09 37.6 6.6 0.0084 15.3 0.8 4.4 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM21228.1 - 1.1e-07 32.0 0.4 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM21228.1 - 3.9e-07 29.4 0.3 0.013 15.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAM21228.1 - 1.1e-06 29.1 0.0 0.022 15.2 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 GAM21228.1 - 3.2e-06 27.3 4.0 0.47 10.3 0.1 5.0 3 2 1 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 GAM21228.1 - 8e-06 25.8 0.2 0.23 11.3 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 GAM21228.1 - 5.4e-05 22.4 1.2 0.011 14.9 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM21228.1 - 0.00033 21.0 4.5 0.13 12.5 0.1 3.4 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.8 GAM21228.1 - 0.00047 19.1 0.2 0.51 9.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) T2SE PF00437.15 GAM21228.1 - 0.0013 17.7 0.0 1.5 7.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 GAM21228.1 - 0.0017 17.7 0.4 2.9 7.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 GAM21228.1 - 0.0018 17.4 2.3 0.094 11.7 0.1 2.7 3 0 0 3 3 2 1 Zeta toxin AAA_17 PF13207.1 GAM21228.1 - 0.0018 19.0 0.1 2.3 9.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 GAM21228.1 - 0.003 17.0 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.1 GAM21228.1 - 0.0034 16.9 0.8 8.1 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 GAM21228.1 - 0.0047 17.0 0.9 0.58 10.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM21228.1 - 0.0054 16.2 0.3 4.3 6.6 0.1 3.0 3 0 0 3 3 3 1 AAA-like domain TrwB_AAD_bind PF10412.4 GAM21228.1 - 0.01 14.5 0.1 2.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 GAM21228.1 - 0.018 14.4 0.9 0.14 11.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 GAM21228.1 - 0.044 13.9 0.1 10 6.3 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 GAM21228.1 - 0.054 13.3 2.5 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 GAM21228.1 - 0.064 12.9 0.6 2.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM21228.1 - 0.081 12.7 8.9 0.049 13.4 0.3 3.1 3 0 0 3 3 3 0 Dynamin family Mit_KHE1 PF10173.4 GAM21228.1 - 0.21 11.4 2.8 0.53 10.1 1.9 1.6 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TLD PF07534.11 GAM21229.1 - 1.5e-37 128.6 0.2 6.9e-37 126.5 0.1 2.2 3 0 0 3 3 3 1 TLD RRM_1 PF00076.17 GAM21230.1 - 3.5e-32 109.8 0.4 1.1e-15 56.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21230.1 - 9.8e-24 83.1 0.1 3.2e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21230.1 - 8.1e-08 32.0 0.2 0.00044 20.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_2 PF02210.19 GAM21230.1 - 0.013 15.5 0.2 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Laminin G domain HAP1_N PF04849.8 GAM21231.1 - 0.13 11.2 13.8 0.19 10.6 9.6 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region BLOC1_2 PF10046.4 GAM21231.1 - 0.39 10.8 7.2 1.8 8.7 5.0 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.9 GAM21231.1 - 1.4 8.4 12.2 1.3 8.6 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.7 GAM21231.1 - 1.5 9.2 6.6 0.41 11.0 1.6 2.2 2 1 0 2 2 2 0 SlyX DUF641 PF04859.7 GAM21231.1 - 3.8 7.2 9.1 1.8 8.3 4.3 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Adeno_E4_ORF3 PF06931.6 GAM21232.1 - 0.16 12.0 0.3 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Mastadenovirus E4 ORF3 protein Col_cuticle_N PF01484.12 GAM21232.1 - 0.46 10.2 2.3 9.8 5.9 0.1 2.4 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain FNIP PF05725.7 GAM21233.1 - 4.1e-31 106.6 13.0 6.6e-11 41.9 0.0 4.6 2 1 3 6 6 6 5 FNIP Repeat F-box PF00646.28 GAM21233.1 - 0.0038 16.8 0.3 0.014 15.0 0.2 2.0 1 0 0 1 1 1 1 F-box domain Acyl_CoA_thio PF02551.10 GAM21234.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA thioesterase Peptidase_S28 PF05577.7 GAM21236.1 - 3.5e-80 269.6 6.2 8.7e-80 268.4 4.3 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAM21236.1 - 0.0018 18.2 0.0 0.0063 16.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM21236.1 - 0.013 15.1 0.5 0.013 15.1 0.3 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold zf-CCHC_3 PF13917.1 GAM21237.1 - 7.4e-06 25.6 0.6 7.4e-06 25.6 0.4 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 GAM21237.1 - 0.023 14.6 1.8 0.038 13.9 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle YL1 PF05764.8 GAM21237.1 - 0.052 13.1 31.2 0.062 12.9 21.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Serinc PF03348.10 GAM21237.1 - 0.1 11.3 1.9 0.13 10.9 1.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SprA-related PF12118.3 GAM21237.1 - 0.17 11.1 13.7 0.19 11.0 9.5 1.1 1 0 0 1 1 1 0 SprA-related family GAGA_bind PF06217.7 GAM21237.1 - 0.46 10.3 14.1 0.51 10.2 9.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 GAM21237.1 - 0.58 9.9 13.9 0.63 9.8 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 GAM21237.1 - 0.97 8.7 24.3 1.2 8.4 16.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 GAM21237.1 - 1.2 8.8 12.0 1.7 8.3 8.3 1.4 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 GAM21237.1 - 1.7 6.6 27.4 2 6.3 19.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 GAM21237.1 - 1.7 7.5 15.0 2.2 7.1 10.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Apt1 PF10351.4 GAM21237.1 - 4.5 6.0 19.7 5.6 5.7 13.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain An_peroxidase PF03098.10 GAM21238.1 - 2.7e-119 398.9 0.0 3.2e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase TraG_N PF07916.6 GAM21241.1 - 0.00017 20.2 0.0 0.0023 16.4 0.1 2.1 2 0 0 2 2 2 2 TraG-like protein, N-terminal region SPRY PF00622.23 GAM21242.1 - 1.4e-08 34.8 0.1 2.7e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.2 GAM21242.1 - 8.3e-06 25.4 0.1 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM21242.1 - 0.02 14.5 0.2 0.02 14.5 0.2 2.0 2 0 0 2 2 2 0 F-box domain DUF1843 PF08898.5 GAM21242.1 - 0.18 11.9 1.0 0.66 10.0 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Det1 PF09737.4 GAM21243.1 - 9.8e-105 350.6 8.2 5e-76 256.0 2.6 2.5 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 Mucin PF01456.12 GAM21243.1 - 0.0038 17.0 21.0 0.0038 17.0 14.5 4.3 4 1 0 4 4 4 1 Mucin-like glycoprotein Homeobox PF00046.24 GAM21244.1 - 4.9e-18 64.5 12.3 4.7e-09 35.7 0.5 3.5 3 0 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.6 GAM21244.1 - 5.2e-06 26.0 0.9 0.24 11.1 0.0 3.8 3 0 0 3 3 3 2 Homeobox KN domain HTH_17 PF12728.2 GAM21244.1 - 0.0086 16.3 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain CENP-B_N PF04218.8 GAM21244.1 - 0.018 14.4 0.4 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.1 GAM21244.1 - 0.042 13.5 0.1 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain SSP160 PF06933.6 GAM21244.1 - 2.1 6.2 15.3 3.2 5.6 10.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SSP160 PF06933.6 GAM21245.1 - 9.5 4.0 21.0 0.34 8.8 6.3 2.2 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.20 GAM21246.1 - 7.8e-64 215.3 0.1 1.1e-63 214.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21246.1 - 1.5e-46 158.5 0.1 2.3e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM21246.1 - 0.00079 19.2 0.0 0.0028 17.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM21246.1 - 0.0029 17.2 0.5 0.0051 16.4 0.3 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 GAM21246.1 - 0.0062 15.6 0.2 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM21246.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like FNIP PF05725.7 GAM21248.1 - 6.6e-14 51.5 9.5 1.1e-05 25.3 2.4 3.8 3 1 1 4 4 4 4 FNIP Repeat LRR_4 PF12799.2 GAM21248.1 - 0.15 11.7 3.6 3.5 7.3 0.2 3.7 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM21248.1 - 3.5 8.0 6.3 10 6.5 0.6 4.2 3 1 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.7 GAM21249.1 - 1.5e-12 47.2 1.0 0.00022 21.1 0.0 4.0 2 1 2 4 4 4 4 FNIP Repeat GST_N_3 PF13417.1 GAM21250.1 - 4.7e-11 42.7 0.0 4.2e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM21250.1 - 4.7e-11 42.4 0.1 1.1e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM21250.1 - 2.1e-10 40.4 0.0 5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM21250.1 - 1.5e-09 37.8 0.0 4.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM21250.1 - 1.6e-09 37.5 0.0 4.5e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM21250.1 - 6e-07 29.8 0.1 1.1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Usg PF06233.7 GAM21250.1 - 0.0012 18.6 0.1 0.0026 17.5 0.1 1.6 1 0 0 1 1 1 1 Usg-like family FNIP PF05725.7 GAM21251.1 - 5.1e-12 45.5 6.8 9e-06 25.5 0.2 3.4 2 1 0 2 2 2 2 FNIP Repeat Ion_trans PF00520.26 GAM21252.1 - 5.2e-05 22.5 8.5 5.2e-05 22.5 5.9 1.4 2 0 0 2 2 2 1 Ion transport protein 7tm_3 PF00003.17 GAM21252.1 - 0.019 14.2 0.4 0.029 13.7 0.2 1.3 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR CDC45 PF02724.9 GAM21252.1 - 0.055 11.4 6.5 0.06 11.3 4.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Peptidase_C41 PF05417.6 GAM21252.1 - 0.084 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Hepatitis E cysteine protease ANAPC15 PF15243.1 GAM21252.1 - 0.1 12.6 3.5 0.21 11.6 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Prothymosin PF03247.9 GAM21252.1 - 2.2 8.4 14.0 1.1 9.4 2.9 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family FAM176 PF14851.1 GAM21253.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 FAM176 family BAF1_ABF1 PF04684.8 GAM21253.1 - 0.8 8.4 9.9 3.2 6.5 0.1 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor E1-E2_ATPase PF00122.15 GAM21255.1 - 1.3e-17 63.6 0.0 4.4e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAM21255.1 - 1.4e-17 64.4 0.0 4.8e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM21255.1 - 2.5e-16 60.7 0.1 8.2e-15 55.7 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM21255.1 - 4.7e-15 55.3 0.1 3.5e-14 52.5 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM21255.1 - 0.0002 21.0 0.4 0.0036 16.9 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ead_Ea22 PF13935.1 GAM21256.1 - 0.0015 18.8 0.7 0.0027 18.0 0.5 1.4 1 0 0 1 1 1 1 Ead/Ea22-like protein Fijivirus_P9-2 PF06837.6 GAM21256.1 - 4.4 6.3 5.7 6.7 5.7 3.9 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein ABC_membrane PF00664.18 GAM21257.1 - 6.6e-70 235.6 31.3 6.8e-39 133.9 9.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM21257.1 - 6.8e-52 175.4 0.1 9e-30 103.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM21257.1 - 1e-09 37.9 5.8 0.0088 15.2 0.3 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM21257.1 - 5.8e-08 32.1 0.3 0.0021 17.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 GAM21257.1 - 1.2e-07 31.9 0.9 0.42 10.5 0.2 4.5 2 2 1 4 4 4 2 AAA domain AAA_16 PF13191.1 GAM21257.1 - 2.9e-07 30.6 0.6 0.0081 16.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 GAM21257.1 - 1.3e-06 28.8 0.2 0.018 15.5 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 GAM21257.1 - 1.5e-05 24.9 1.5 0.16 11.9 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM21257.1 - 7.8e-05 23.0 3.2 0.096 12.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAM21257.1 - 7.8e-05 21.9 1.3 0.016 14.4 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF815 PF05673.8 GAM21257.1 - 0.00018 20.5 0.5 0.48 9.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 GAM21257.1 - 0.00026 20.1 0.9 0.022 13.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 GAM21257.1 - 0.0003 19.7 0.1 0.36 9.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 GAM21257.1 - 0.00083 18.8 0.0 0.42 10.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM21257.1 - 0.00088 20.0 0.0 0.98 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM21257.1 - 0.0011 18.5 0.6 5.4 6.5 0.1 3.7 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 GAM21257.1 - 0.0024 17.3 0.7 3.6 6.9 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 GAM21257.1 - 0.0035 17.4 0.7 0.4 10.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 GAM21257.1 - 0.012 15.0 0.7 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 GAM21257.1 - 0.017 13.7 0.9 3 6.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 GAM21257.1 - 0.019 14.7 6.2 0.034 13.9 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_10 PF12846.2 GAM21257.1 - 0.03 13.7 1.9 3 7.1 0.1 3.0 4 0 0 4 4 3 0 AAA-like domain Pex24p PF06398.6 GAM21257.1 - 0.041 12.6 3.5 0.092 11.5 2.4 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin AAA_18 PF13238.1 GAM21257.1 - 0.049 13.9 0.0 22 5.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 GAM21257.1 - 0.057 13.2 2.5 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 GAM21257.1 - 0.078 12.6 0.9 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAM21257.1 - 0.095 12.8 0.5 12 6.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 GAM21257.1 - 0.12 11.8 0.8 0.69 9.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 GAM21257.1 - 0.45 10.2 2.2 0.99 9.2 0.2 2.6 3 0 0 3 3 2 0 Part of AAA domain Mit_KHE1 PF10173.4 GAM21257.1 - 0.45 10.3 2.1 1.3 8.8 1.5 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related 4HBT_2 PF13279.1 GAM21258.1 - 7.2e-07 29.6 0.0 8.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DDE_Tnp_4 PF13359.1 GAM21259.1 - 1.4e-21 76.7 0.7 4.9e-20 71.7 0.4 3.1 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM21259.1 - 1.5e-07 31.1 0.9 1.5e-07 31.1 0.6 1.7 2 0 0 2 2 2 1 Transposase DDE domain DUF2360 PF10152.4 GAM21259.1 - 0.0021 18.3 15.2 0.0052 17.0 1.3 2.9 3 0 0 3 3 3 2 Predicted coiled-coil domain-containing protein (DUF2360) DUF533 PF04391.7 GAM21259.1 - 0.23 10.8 4.2 0.5 9.7 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Herpes_capsid PF06112.6 GAM21260.1 - 1.3 9.0 6.6 2.6 8.0 4.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAA_hydrolase PF01557.13 GAM21261.1 - 3.2e-65 219.6 0.0 4.8e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HMG_box PF00505.14 GAM21262.1 - 3.7e-17 62.3 1.6 3.7e-17 62.3 1.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM21262.1 - 4.9e-13 49.2 0.9 4.9e-13 49.2 0.6 2.1 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 GAM21262.1 - 2.3e-05 24.6 2.3 2.3e-05 24.6 1.6 1.5 1 1 1 2 2 2 1 YABBY protein CHDNT PF08073.7 GAM21262.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain MCM PF00493.18 GAM21262.1 - 0.092 11.5 2.1 0.13 11.0 1.5 1.1 1 0 0 1 1 1 0 MCM2/3/5 family SAGA-Tad1 PF12767.2 GAM21262.1 - 0.6 9.7 8.6 0.7 9.5 6.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SR-25 PF10500.4 GAM21262.1 - 7.2 6.0 36.5 0.52 9.7 17.2 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein LIM PF00412.17 GAM21263.1 - 1.9e-37 127.1 52.5 2.8e-12 46.5 4.9 4.5 4 0 0 4 4 4 4 LIM domain RRM_1 PF00076.17 GAM21264.1 - 4e-37 125.6 0.3 4.3e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21264.1 - 6.2e-27 93.3 0.1 6.8e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21264.1 - 2.3e-13 49.7 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 GAM21264.1 - 0.043 13.6 0.1 0.77 9.5 0.0 2.3 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain DbpA PF03880.10 GAM21264.1 - 0.055 13.1 0.1 0.14 11.8 0.0 1.7 1 1 0 1 1 1 0 DbpA RNA binding domain Limkain-b1 PF11608.3 GAM21264.1 - 0.06 13.1 0.3 3.2 7.5 0.0 3.1 2 2 0 2 2 2 0 Limkain b1 OB_RNB PF08206.6 GAM21264.1 - 0.086 12.3 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain zf-C4H2 PF10146.4 GAM21265.1 - 0.0045 17.0 1.8 0.0045 17.0 1.2 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein ARL2_Bind_BART PF11527.3 GAM21265.1 - 0.0081 15.9 4.0 0.012 15.3 2.1 1.7 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART DUF4498 PF14926.1 GAM21265.1 - 0.015 14.4 0.7 0.018 14.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4498) EAP30 PF04157.11 GAM21265.1 - 0.1 11.7 1.9 0.14 11.3 1.3 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family DUF4201 PF13870.1 GAM21265.1 - 0.12 11.8 7.8 0.078 12.4 4.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF2443 PF10398.4 GAM21265.1 - 0.14 11.9 2.5 1.1 9.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2443) IncA PF04156.9 GAM21265.1 - 0.32 10.5 3.0 0.45 10.0 1.9 1.3 1 1 0 1 1 1 0 IncA protein Med9 PF07544.8 GAM21265.1 - 0.98 9.2 5.1 1.2 8.8 0.8 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 COMP PF11598.3 GAM21265.1 - 3.7 7.7 7.0 1.9e+02 2.2 4.8 2.5 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein UPF0020 PF01170.13 GAM21266.1 - 1.5e-18 67.0 0.1 1.2e-12 47.7 0.0 3.0 2 1 1 3 3 3 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 GAM21266.1 - 4e-07 30.0 0.0 8.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 GAM21266.1 - 0.017 14.6 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 DNA methylase MCPVI PF02993.9 GAM21266.1 - 5.8 6.9 6.2 6.9 6.7 3.1 1.8 1 1 1 2 2 2 0 Minor capsid protein VI FNIP PF05725.7 GAM21267.1 - 2.9e-51 171.1 0.2 1.1e-11 44.4 0.1 8.2 5 2 3 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM21267.1 - 3.9e-05 23.5 1.8 3.1 7.8 0.0 5.7 5 1 1 6 6 6 1 Protein of unknown function (DUF1769) LRR_8 PF13855.1 GAM21267.1 - 0.00037 20.1 0.3 0.024 14.3 0.1 3.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 GAM21267.1 - 0.27 11.5 2.7 17 6.2 0.0 5.2 6 1 1 7 7 7 0 Leucine rich repeat Robl_LC7 PF03259.12 GAM21268.1 - 0.0015 18.0 0.1 0.0046 16.5 0.1 1.7 1 0 0 1 1 1 1 Roadblock/LC7 domain SPT16 PF08644.6 GAM21269.1 - 0.037 13.8 3.2 0.092 12.5 2.2 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DnaB PF00772.16 GAM21269.1 - 0.15 11.9 2.6 1 9.2 0.1 3.4 3 1 0 3 3 3 0 DnaB-like helicase N terminal domain TFIIF_beta PF02270.10 GAM21270.1 - 3.3e-48 164.8 6.1 1.2e-35 123.7 4.7 2.0 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 GAM21270.1 - 0.00018 20.9 0.4 0.00019 20.8 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DDE_Tnp_IS66_C PF13817.1 GAM21270.1 - 0.0018 18.2 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 1 IS66 C-terminal element GN3L_Grn1 PF08701.6 GAM21271.1 - 1.1e-20 73.3 15.5 1.1e-20 73.3 10.7 4.5 3 2 2 5 5 5 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 GAM21271.1 - 8.8e-18 64.3 0.4 3.5e-14 52.7 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM21271.1 - 2.1e-09 36.8 0.1 3e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM21271.1 - 0.00044 19.7 1.2 0.047 13.1 0.0 3.5 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 GAM21271.1 - 0.00047 19.3 0.3 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM21271.1 - 0.18 11.7 5.7 0.33 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 GAM21271.1 - 0.19 12.2 0.0 0.19 12.2 0.0 3.4 3 1 0 3 3 3 0 Miro-like protein AAA_18 PF13238.1 GAM21271.1 - 0.36 11.1 0.0 0.36 11.1 0.0 4.4 3 2 1 4 4 4 0 AAA domain ACOX PF01756.14 GAM21272.1 - 3e-28 98.4 0.1 4.8e-28 97.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAM21272.1 - 4.3e-16 58.1 0.4 9.3e-16 57.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM21272.1 - 1.1e-05 25.5 0.4 6.4e-05 23.0 0.3 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 GAM21273.1 - 7.5e-27 93.9 0.1 1.5e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAM21273.1 - 3.3e-14 52.1 0.2 7.1e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM21273.1 - 4.1e-06 26.9 0.0 9.5e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CBM49 PF09478.5 GAM21274.1 - 2.2e-06 27.6 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PT PF04886.7 GAM21274.1 - 0.059 12.6 0.8 0.059 12.6 0.5 3.9 1 1 1 2 2 2 0 PT repeat SpoIIIAH PF12685.2 GAM21274.1 - 0.074 12.5 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Lactamase_B_2 PF12706.2 GAM21275.1 - 6e-40 136.8 1.0 7.8e-40 136.4 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM21275.1 - 1.4e-18 67.0 0.0 2.8e-18 66.1 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM21275.1 - 0.037 13.6 1.7 0.69 9.5 0.6 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily AMP-binding PF00501.23 GAM21276.1 - 9.3e-105 350.3 0.0 1.2e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SH3_1 PF00018.23 GAM21276.1 - 0.085 12.2 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 SH3 domain RhoGAP PF00620.22 GAM21277.1 - 6.5e-20 71.2 0.0 2.7e-19 69.2 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain Nucleoplasmin PF03066.10 GAM21277.1 - 0.17 11.4 15.9 0.7 9.3 0.3 2.5 2 0 0 2 2 2 0 Nucleoplasmin P53 PF00870.13 GAM21277.1 - 0.19 11.3 1.1 0.33 10.5 0.8 1.4 1 0 0 1 1 1 0 P53 DNA-binding domain RNase_H2_suC PF08615.6 GAM21277.1 - 0.84 9.4 5.3 7.6 6.3 0.2 2.5 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) PPP4R2 PF09184.6 GAM21277.1 - 0.95 8.9 27.3 0.16 11.5 12.4 2.2 2 0 0 2 2 2 0 PPP4R2 BSP_II PF05432.6 GAM21277.1 - 1.2 8.3 20.2 0.07 12.4 1.3 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) GST_N_2 PF13409.1 GAM21278.1 - 2.1e-23 82.1 0.0 9e-23 80.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM21278.1 - 3.9e-15 55.4 0.0 4.5e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM21278.1 - 7.6e-10 38.6 0.1 1.7e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM21278.1 - 3e-07 30.8 0.0 1.1e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM21278.1 - 1.4e-05 25.2 0.1 0.00032 20.8 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain P4Ha_N PF08336.6 GAM21278.1 - 0.059 13.1 0.5 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cna_B PF05738.8 GAM21279.1 - 2.3e-09 36.9 0.0 1.9e-08 33.9 0.0 9.3 10 1 0 10 10 10 3 Cna protein B-type domain Peptidase_C48 PF02902.14 GAM21280.1 - 7e-31 107.5 1.8 5.6e-30 104.5 1.3 2.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Aldedh PF00171.17 GAM21281.1 - 1.5e-82 277.3 0.0 1.8e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fib_alpha PF08702.5 GAM21281.1 - 0.036 14.1 1.2 0.15 12.2 0.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Metallophos PF00149.23 GAM21282.1 - 5.1e-14 52.1 0.2 8.6e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM21282.1 - 5e-08 32.9 0.2 1.1e-07 31.7 0.2 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 GAM21282.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 GAM21282.1 - 3.9e-05 22.4 0.0 5.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Methuselah_N PF06652.7 GAM21282.1 - 0.078 12.5 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Methuselah N-terminus RhoGEF PF00621.15 GAM21283.1 - 1.2e-43 149.0 7.9 1.2e-43 149.0 5.5 1.8 2 0 0 2 2 2 1 RhoGEF domain Borrelia_lipo_2 PF06238.6 GAM21283.1 - 0.0066 16.4 0.5 0.016 15.2 0.3 1.6 1 0 0 1 1 1 1 Borrelia burgdorferi BBR25 lipoprotein DZR PF12773.2 GAM21283.1 - 0.2 11.5 15.7 0.42 10.4 10.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM21283.1 - 0.91 8.8 4.2 1.9 7.8 2.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF2294 PF10057.4 GAM21284.1 - 0.097 12.3 0.7 0.2 11.3 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) RhoGAP PF00620.22 GAM21285.1 - 4.6e-30 104.2 0.0 1.3e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain COX5A PF02284.11 GAM21285.1 - 0.076 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va SIR2 PF02146.12 GAM21286.1 - 7.1e-50 169.1 0.0 1.1e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 GAM21286.1 - 0.00088 19.0 0.1 0.0042 16.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2933 PF11666.3 GAM21286.1 - 0.81 9.2 5.4 1.8 8.1 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) DUF4206 PF13901.1 GAM21287.1 - 4.5e-65 219.0 11.5 4.5e-65 219.0 8.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4206) RUN PF02759.14 GAM21287.1 - 1.3e-12 47.6 0.1 3.7e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 RUN domain Spt4 PF06093.8 GAM21287.1 - 0.086 12.7 4.5 0.34 10.8 3.1 2.1 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Ribosomal_L39 PF00832.15 GAM21288.1 - 1.4e-22 78.8 9.9 1.6e-22 78.6 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Toxin_YhaV PF11663.3 GAM21288.1 - 0.26 11.0 1.9 0.38 10.4 1.3 1.4 1 1 0 1 1 1 0 Toxin with endonuclease activity YhaV Yae1_N PF09811.4 GAM21289.1 - 2.1e-08 33.5 0.1 2.9e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RCC1 PF00415.13 GAM21290.1 - 4.5e-39 132.4 6.2 8.4e-15 54.7 0.0 4.7 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM21290.1 - 5.1e-20 70.5 15.1 5.7e-08 32.1 0.1 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 GAM21290.1 - 0.98 9.1 4.0 11 5.7 0.1 3.1 3 0 0 3 3 3 0 SUKH-3 immunity protein Acyl-CoA_dh_C PF12806.2 GAM21291.1 - 0.0009 19.1 1.0 0.33 10.8 0.3 2.4 2 0 0 2 2 2 2 Acetyl-CoA dehydrogenase C-terminal like RWD PF05773.17 GAM21291.1 - 0.03 14.2 2.2 0.05 13.5 0.1 2.5 2 0 0 2 2 2 0 RWD domain YqeY PF09424.5 GAM21291.1 - 0.19 11.5 2.4 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Yqey-like protein 60KD_IMP PF02096.15 GAM21292.1 - 3.3e-33 115.0 5.2 4.4e-33 114.6 3.6 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein TMA7 PF09072.5 GAM21293.1 - 0.11 13.0 0.6 0.11 13.0 0.4 3.2 3 1 1 4 4 4 0 Translation machinery associated TMA7 MAPEG PF01124.13 GAM21294.1 - 5.8e-24 84.1 0.8 6.9e-24 83.9 0.6 1.1 1 0 0 1 1 1 1 MAPEG family zf-NF-X1 PF01422.12 GAM21295.1 - 4.9e-08 32.7 87.1 1.9e-05 24.4 9.1 14.4 13 2 2 15 15 15 6 NF-X1 type zinc finger Glyco_transf_21 PF13506.1 GAM21295.1 - 0.052 12.8 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2414 PF10309.4 GAM21295.1 - 0.076 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) DUF3244 PF11589.3 GAM21296.1 - 0.0027 17.4 0.0 8.8 6.0 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF3244) Hormone_4 PF00220.12 GAM21296.1 - 2.1 8.2 8.0 0.16 11.6 1.9 2.1 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Methyltransf_4 PF02390.12 GAM21297.1 - 2.4e-47 160.5 0.0 3.2e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 GAM21297.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM21297.1 - 0.0048 17.3 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 GAM21297.1 - 0.0062 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 GAM21297.1 - 0.0067 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM21297.1 - 0.0097 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 GAM21297.1 - 0.01 16.4 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 GAM21297.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain eIF-6 PF01912.13 GAM21298.1 - 5e-78 260.7 0.4 1.1e-77 259.6 0.3 1.5 2 0 0 2 2 2 1 eIF-6 family Sec63 PF02889.11 GAM21299.1 - 9.8e-199 659.0 2.3 4.9e-102 341.3 0.2 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 GAM21299.1 - 1.1e-48 164.9 1.7 1.3e-26 93.0 0.2 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM21299.1 - 6.5e-14 51.5 0.0 1.1e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PhoH PF02562.11 GAM21299.1 - 0.018 14.2 0.0 0.27 10.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ADH_zinc_N PF00107.21 GAM21300.1 - 8.3e-14 51.2 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM21300.1 - 1.4e-08 34.4 0.1 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UNC45-central PF11701.3 GAM21301.1 - 0.0053 16.4 2.1 0.018 14.6 0.1 2.7 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central SMC_N PF02463.14 GAM21303.1 - 2e-61 207.0 59.6 2.5e-32 111.9 15.6 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM21303.1 - 1.5e-28 99.2 1.0 5.4e-28 97.3 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 GAM21303.1 - 3.9e-12 46.7 17.0 9.4e-07 29.0 0.1 3.7 2 2 1 3 3 3 2 AAA domain AAA_23 PF13476.1 GAM21303.1 - 5.1e-12 46.5 15.6 5.1e-12 46.5 10.8 8.1 4 2 1 5 5 5 1 AAA domain AAA_29 PF13555.1 GAM21303.1 - 6.6e-07 28.7 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 GAM21303.1 - 0.00019 20.7 39.3 0.0003 20.0 1.2 5.7 2 2 1 5 5 5 4 Reovirus sigma C capsid protein AAA_16 PF13191.1 GAM21303.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.5 4 1 0 4 4 4 0 AAA ATPase domain RhoGEF PF00621.15 GAM21304.1 - 5.1e-53 179.6 0.6 8e-53 178.9 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAM21304.1 - 6.5e-21 74.0 7.1 6.5e-21 74.0 4.9 1.9 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 GAM21304.1 - 4.1e-07 30.1 0.0 8.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 GAM21304.1 - 0.0057 16.5 5.0 0.0057 16.5 3.4 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger PEP-utilisers_N PF05524.8 GAM21304.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal IBR PF01485.16 GAM21304.1 - 0.91 9.4 8.6 0.073 12.9 2.3 1.9 2 0 0 2 2 2 0 IBR domain zf-C3HC4_2 PF13923.1 GAM21304.1 - 1.6 8.8 8.2 6.9 6.7 5.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 GAM21304.1 - 2.4 7.8 5.3 3.4 7.3 3.1 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-B_box PF00643.19 GAM21304.1 - 4.7 7.2 10.2 1.9 8.4 5.0 1.9 2 0 0 2 2 2 0 B-box zinc finger TAP_C PF03943.8 GAM21305.1 - 3.6e-09 35.8 0.1 6.2e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 GAM21305.1 - 9e-09 35.7 0.1 2.6e-08 34.2 0.1 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 GAM21305.1 - 1.1e-06 28.1 0.1 2.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain LRR_9 PF14580.1 GAM21305.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 GAM21305.1 - 0.0059 16.2 0.6 0.0059 16.2 0.4 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) RRM_6 PF14259.1 GAM21306.1 - 0.054 13.4 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 GAM21307.1 - 8.7e-16 57.9 0.0 4.2e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain RA PF00788.18 GAM21307.1 - 4.1e-14 52.8 0.0 8.1e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain PH PF00169.24 GAM21307.1 - 0.0028 17.8 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 PH domain polyprenyl_synt PF00348.12 GAM21308.1 - 6.2e-49 166.1 0.0 7.3e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Plasmid_Txe PF06769.8 GAM21308.1 - 0.026 14.3 0.8 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Plasmid encoded toxin Txe RE_R_Pab1 PF09522.5 GAM21308.1 - 0.033 14.1 0.2 5.7 6.8 0.1 2.4 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease FAA_hydrolase PF01557.13 GAM21309.1 - 8.2e-66 221.5 0.0 1.1e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SR-25 PF10500.4 GAM21310.1 - 0.095 12.1 16.7 0.11 11.9 11.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3827 PF12877.2 GAM21310.1 - 0.92 7.5 7.5 0.96 7.4 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MACPF PF01823.14 GAM21310.1 - 1.3 8.6 7.6 1.4 8.5 5.3 1.0 1 0 0 1 1 1 0 MAC/Perforin domain Sox_N PF12444.3 GAM21310.1 - 6.1 8.0 9.7 7.1 7.8 6.7 1.1 1 0 0 1 1 1 0 Sox developmental protein N terminal DUF4614 PF15391.1 GAM21310.1 - 6.3 6.5 8.2 6.5 6.4 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDC45 PF02724.9 GAM21310.1 - 6.9 4.5 12.0 6.8 4.5 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein HCaRG PF07258.9 GAM21311.1 - 7e-14 51.7 0.2 7.2e-14 51.7 0.2 1.0 1 0 0 1 1 1 1 HCaRG protein DHC_N1 PF08385.7 GAM21311.1 - 0.012 13.9 0.1 0.015 13.7 0.1 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DPBB_1 PF03330.13 GAM21311.1 - 0.055 13.4 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4210 PF13915.1 GAM21311.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) Amidohydro_2 PF04909.9 GAM21312.1 - 2.3e-18 66.7 0.0 3.4e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase RRM_1 PF00076.17 GAM21313.1 - 4.8e-16 58.1 0.0 7.2e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21313.1 - 4.3e-11 42.6 0.0 6.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21313.1 - 2.7e-09 36.7 0.0 3.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM21313.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 TRAP_alpha PF03896.11 GAM21314.1 - 0.0038 16.2 4.3 0.0038 16.2 3.0 1.6 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit DUF2052 PF09747.4 GAM21314.1 - 0.8 9.6 17.9 0.27 11.1 5.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Spore_coat_CotO PF14153.1 GAM21314.1 - 2.6 7.4 21.4 0.28 10.5 5.1 2.4 2 0 0 2 2 2 0 Spore coat protein CotO Abhydro_lipase PF04083.11 GAM21316.1 - 1.3e-14 53.3 0.0 3.1e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 GAM21316.1 - 1.4e-09 37.8 0.0 6.1e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM21316.1 - 7.5e-08 32.2 0.0 8e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM21316.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM21316.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase WD40 PF00400.27 GAM21317.1 - 2.9e-17 61.8 10.3 4.6e-07 29.4 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Adeno_E1B_55K PF01696.12 GAM21317.1 - 0.011 14.2 0.2 0.018 13.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen zf-UBR PF02207.15 GAM21318.1 - 1.4e-12 47.1 11.2 1.4e-12 47.1 7.7 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 GAM21318.1 - 0.0055 16.5 2.7 0.0055 16.5 1.9 3.4 4 0 0 4 4 4 1 Ring finger domain ELL PF10390.4 GAM21318.1 - 2.3 7.3 6.6 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL PhzC-PhzF PF02567.11 GAM21319.1 - 1.3e-52 178.7 0.0 1.5e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 GAM21319.1 - 1.1e-05 24.4 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Proline racemase Reg_prop PF07494.6 GAM21319.1 - 0.1 12.6 0.2 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Two component regulator propeller UCH PF00443.24 GAM21320.1 - 2.2e-55 187.6 4.2 7.9e-55 185.8 2.9 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM21320.1 - 3e-15 56.4 2.3 6.9e-13 48.6 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase eIF-5_eIF-2B PF01873.12 GAM21320.1 - 0.044 13.4 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Glyco_transf_10 PF00852.14 GAM21321.1 - 1.3e-41 142.3 2.0 4.4e-41 140.6 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase family 10 (fucosyltransferase) Glyco_trans_1_2 PF13524.1 GAM21321.1 - 0.00018 21.7 0.0 0.00036 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1510 PF07423.6 GAM21321.1 - 0.00055 19.3 0.3 0.0011 18.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 GAM21321.1 - 0.0023 15.7 0.1 0.0031 15.3 0.0 1.1 1 0 0 1 1 1 1 Ycf1 DUF1183 PF06682.7 GAM21321.1 - 0.026 14.1 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Pex16 PF08610.5 GAM21321.1 - 0.3 10.0 0.7 0.75 8.7 0.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Neur_chan_memb PF02932.11 GAM21321.1 - 0.34 10.7 2.9 0.61 9.9 2.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Conotoxin PF02950.12 GAM21321.1 - 1.9 9.3 7.2 0.65 10.8 0.1 2.5 1 1 1 2 2 2 0 Conotoxin FNIP PF05725.7 GAM21322.1 - 1.1e-58 194.9 38.1 9.9e-15 54.2 3.1 9.2 6 2 4 10 10 10 9 FNIP Repeat Nbl1_Borealin_N PF10444.4 GAM21322.1 - 0.062 12.6 0.0 2 7.8 0.0 2.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal TauE PF01925.14 GAM21323.1 - 3.7e-25 88.7 24.2 1.3e-12 47.7 0.7 2.3 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Sigma_reg_N PF13800.1 GAM21323.1 - 5.4 7.1 11.1 0.51 10.3 0.7 3.4 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Zn_clus PF00172.13 GAM21324.1 - 1.2e-06 28.2 9.2 2e-06 27.5 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAGP PF05507.6 GAM21324.1 - 0.021 14.6 6.1 0.15 11.8 4.2 2.4 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) SNARE PF05739.14 GAM21325.1 - 3.1e-18 65.1 5.8 3.1e-18 65.1 4.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAM21325.1 - 3.1e-15 56.1 4.0 3.1e-15 56.1 2.8 2.7 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 GAM21325.1 - 0.0011 18.9 16.4 0.0028 17.6 5.8 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin-6_N PF09177.6 GAM21325.1 - 0.018 15.4 9.3 0.029 14.7 1.7 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 GAM21325.1 - 0.024 14.1 0.8 0.024 14.1 0.6 2.5 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Viral_Beta_CD PF04530.7 GAM21325.1 - 0.042 14.0 0.6 0.22 11.6 0.0 2.4 2 1 1 3 3 3 0 Viral Beta C/D like family VitD-bind_III PF09164.5 GAM21325.1 - 0.048 13.2 1.2 0.78 9.3 0.1 2.4 2 0 0 2 2 2 0 Vitamin D binding protein, domain III 7tm_1 PF00001.16 GAM21325.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Med9 PF07544.8 GAM21325.1 - 0.11 12.2 3.4 2.3 7.9 0.0 3.3 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 WXG100 PF06013.7 GAM21325.1 - 0.16 11.9 5.6 13 5.8 0.0 4.3 4 1 0 5 5 5 0 Proteins of 100 residues with WXG DUF4094 PF13334.1 GAM21325.1 - 0.37 11.1 4.5 0.41 11.0 0.6 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4094) Allexi_40kDa PF05549.6 GAM21325.1 - 3 7.0 11.3 1.3 8.3 2.4 2.4 2 1 1 3 3 3 0 Allexivirus 40kDa protein UPF0118 PF01594.11 GAM21325.1 - 3 6.7 7.3 3.9 6.3 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF20 AATF-Che1 PF13339.1 GAM21325.1 - 3.1 7.9 9.9 0.69 10.0 3.4 2.4 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor RRP7 PF12923.2 GAM21326.1 - 8.6e-28 96.9 12.3 8.6e-28 96.9 8.5 4.5 3 1 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) Tim17 PF02466.14 GAM21327.1 - 4.7e-07 29.8 3.7 8.5e-07 29.0 2.4 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SWIM PF04434.12 GAM21328.1 - 1.9e-06 27.2 0.7 3.4e-06 26.4 0.5 1.3 1 0 0 1 1 1 1 SWIM zinc finger Baculo_LEF-10 PF07206.6 GAM21328.1 - 0.0056 16.2 0.3 0.024 14.2 0.0 2.2 2 1 0 2 2 2 1 Baculovirus late expression factor 10 (LEF-10) Hep_core_N PF08290.6 GAM21328.1 - 0.2 11.1 1.5 0.42 10.0 1.0 1.5 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger SNARE PF05739.14 GAM21329.1 - 2.2e-13 49.6 1.2 8.3e-13 47.8 0.8 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 GAM21329.1 - 7.1e-09 35.7 1.4 7.1e-09 35.7 0.9 3.4 4 0 0 4 4 4 1 Syntaxin MCPsignal PF00015.16 GAM21329.1 - 0.15 11.6 6.3 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Swi5 PF07061.6 GAM21330.1 - 3.8e-14 52.2 4.3 5e-14 51.8 3.0 1.2 1 0 0 1 1 1 1 Swi5 ERM PF00769.14 GAM21330.1 - 0.00082 18.9 2.7 0.00096 18.7 1.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Occludin_ELL PF07303.8 GAM21330.1 - 0.0045 17.7 1.3 0.0065 17.1 0.9 1.2 1 0 0 1 1 1 1 Occludin homology domain TBPIP PF07106.8 GAM21330.1 - 0.014 14.9 4.8 0.026 14.0 3.1 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Golgin_A5 PF09787.4 GAM21330.1 - 0.016 13.7 1.5 0.018 13.5 0.8 1.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF342 PF03961.8 GAM21330.1 - 0.017 13.5 3.8 0.017 13.5 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4600 PF15372.1 GAM21330.1 - 0.019 15.1 4.8 0.034 14.3 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Mnd1 PF03962.10 GAM21330.1 - 0.021 14.4 2.3 0.023 14.3 1.6 1.1 1 0 0 1 1 1 0 Mnd1 family PilO PF04350.8 GAM21330.1 - 0.03 14.2 1.8 0.038 13.8 1.3 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO DUF4164 PF13747.1 GAM21330.1 - 0.033 14.3 0.2 0.044 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF148 PF02520.12 GAM21330.1 - 0.039 13.7 1.7 0.12 12.1 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF972 PF06156.8 GAM21330.1 - 0.049 13.9 1.4 0.078 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4546 PF15079.1 GAM21330.1 - 0.05 12.7 3.6 0.073 12.2 2.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4546) Laminin_II PF06009.7 GAM21330.1 - 0.06 13.1 0.5 0.078 12.7 0.3 1.2 1 0 0 1 1 1 0 Laminin Domain II Z1 PF10593.4 GAM21330.1 - 0.069 12.3 0.4 0.081 12.1 0.3 1.1 1 0 0 1 1 1 0 Z1 domain START PF01852.14 GAM21330.1 - 0.084 12.1 0.1 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 START domain IncA PF04156.9 GAM21330.1 - 0.089 12.3 1.0 0.095 12.2 0.7 1.1 1 0 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 GAM21330.1 - 0.11 11.8 1.3 0.14 11.5 0.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V-SNARE PF05008.10 GAM21330.1 - 0.12 12.5 5.3 0.42 10.8 2.0 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus APG6 PF04111.7 GAM21330.1 - 0.15 11.0 7.1 0.074 12.0 3.5 1.4 1 1 0 2 2 2 0 Autophagy protein Apg6 Phage_GP20 PF06810.6 GAM21330.1 - 0.17 11.3 5.9 0.046 13.1 2.2 1.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Paramyx_P_V_C PF03210.8 GAM21330.1 - 0.18 11.7 3.0 0.25 11.2 0.4 2.0 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal Kinesin-relat_1 PF12711.2 GAM21330.1 - 0.2 12.0 3.4 0.28 11.6 2.3 1.3 1 1 0 1 1 1 0 Kinesin motor Herpes_BLRF2 PF05812.7 GAM21330.1 - 0.51 10.1 6.3 1.1 9.0 2.2 2.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein Seryl_tRNA_N PF02403.17 GAM21330.1 - 0.85 9.6 5.4 3.6 7.6 3.5 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 GAM21330.1 - 4.3 7.6 7.9 0.86 9.9 3.0 1.9 2 1 0 2 2 1 0 Rho Binding FtsJ PF01728.14 GAM21331.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CAP_N PF01213.14 GAM21331.1 - 0.0071 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TMF_DNA_bd PF12329.3 GAM21333.1 - 0.0067 16.2 9.6 0.0067 16.2 6.7 8.0 5 2 3 8 8 8 3 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 GAM21333.1 - 2.5 7.1 27.6 1.5 7.9 1.9 3.5 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Seadorna_VP6 PF07407.6 GAM21333.1 - 9.4 4.8 12.6 1.5 7.5 5.6 1.8 1 1 1 2 2 2 0 Seadornavirus VP6 protein Ank_2 PF12796.2 GAM21334.1 - 8e-33 112.6 2.5 1.5e-10 41.2 0.1 3.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM21334.1 - 1.3e-31 106.7 1.2 1.2e-06 28.0 0.0 5.3 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM21334.1 - 2.7e-26 91.4 1.4 4e-08 33.5 0.0 3.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM21334.1 - 1.1e-23 82.7 0.5 5.6e-08 32.7 0.1 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21334.1 - 1.3e-22 77.5 1.2 3.5e-06 26.7 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeat zf-ribbon_3 PF13248.1 GAM21334.1 - 1.8e-05 23.7 2.5 4e-05 22.6 1.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM21334.1 - 2.2e-05 23.7 2.0 4.9e-05 22.6 1.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 GAM21334.1 - 0.00067 19.4 0.6 0.00067 19.4 0.4 1.6 2 0 0 2 2 2 1 Double zinc ribbon Shigella_OspC PF06128.6 GAM21334.1 - 0.006 16.1 0.4 0.77 9.2 0.1 2.2 2 0 0 2 2 2 2 Shigella flexneri OspC protein UPF0547 PF10571.4 GAM21334.1 - 0.035 13.7 0.9 0.065 12.9 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 C1_1 PF00130.17 GAM21334.1 - 0.066 12.9 1.1 0.13 12.0 0.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Phosphoesterase PF04185.9 GAM21335.1 - 2.4e-75 254.0 5.0 7.3e-45 153.7 0.5 2.2 1 1 1 2 2 2 2 Phosphoesterase family Rhodanese PF00581.15 GAM21336.1 - 3.2e-05 24.2 0.3 0.00061 20.1 0.0 2.7 2 2 0 2 2 2 1 Rhodanese-like domain Vfa1 PF08432.5 GAM21336.1 - 3.2 7.7 23.4 3.6 7.5 6.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.20 GAM21337.1 - 1.3e-44 152.3 0.2 1.3e-44 152.3 0.1 3.0 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21337.1 - 6e-25 87.7 0.0 2.7e-24 85.6 0.0 2.1 1 0 0 1 1 1 1 Protein tyrosine kinase Fib_alpha PF08702.5 GAM21337.1 - 0.0037 17.3 12.0 0.0037 17.3 8.3 5.0 4 1 1 5 5 5 2 Fibrinogen alpha/beta chain family FUSC PF04632.7 GAM21337.1 - 0.0039 15.7 2.1 0.006 15.0 1.4 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family Matrilin_ccoil PF10393.4 GAM21337.1 - 0.45 9.9 14.9 1.7 8.0 0.1 4.6 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin GST_C PF00043.20 GAM21337.1 - 0.52 10.3 4.9 19 5.3 0.0 3.5 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Peptidase_C10 PF01640.12 GAM21337.1 - 0.76 9.5 5.3 2.8 7.6 3.6 1.9 1 0 0 1 1 1 0 Peptidase C10 family AAA_22 PF13401.1 GAM21338.1 - 1e-07 32.1 0.3 0.78 9.8 0.0 5.3 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 GAM21338.1 - 3.4e-07 30.5 0.2 0.00029 21.0 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM21338.1 - 1e-06 28.9 0.0 0.0026 17.7 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain Cys_Met_Meta_PP PF01053.15 GAM21339.1 - 9e-133 442.2 0.1 1.1e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAM21339.1 - 4.8e-05 22.2 0.3 0.00031 19.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V FAD_binding_1 PF00667.15 GAM21340.1 - 4.2e-67 225.7 0.0 6.4e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAM21340.1 - 7.1e-35 120.1 0.2 1.5e-34 119.0 0.1 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 GAM21340.1 - 1.6e-17 64.0 0.0 5.1e-17 62.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-H2C2_2 PF13465.1 GAM21341.1 - 5.5e-05 23.2 0.3 5.5e-05 23.2 0.2 5.1 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2 PF00096.21 GAM21341.1 - 0.0029 17.8 18.2 0.19 12.1 0.1 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type Coiled PF05710.7 GAM21342.1 - 2.3e-12 47.1 27.5 2.7e-12 46.9 19.1 1.0 1 0 0 1 1 1 1 Coiled coil Fork_head_N PF08430.7 GAM21342.1 - 2.4 8.5 10.6 2.7 8.3 7.3 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region Coiled PF05710.7 GAM21343.1 - 2.4e-12 47.1 27.4 2.8e-12 46.9 19.0 1.0 1 0 0 1 1 1 1 Coiled coil Fork_head_N PF08430.7 GAM21343.1 - 2.9 8.3 11.3 3.2 8.1 7.8 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region SNARE PF05739.14 GAM21344.1 - 2.6e-05 23.7 3.3 0.00011 21.7 1.1 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 GAM21344.1 - 0.0034 17.3 1.7 0.033 14.2 0.1 2.3 2 0 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.16 GAM21344.1 - 0.006 16.1 8.2 0.037 13.6 2.6 2.5 2 1 0 2 2 2 1 Synaptobrevin Tup_N PF08581.5 GAM21344.1 - 0.031 14.4 2.7 0.17 12.0 0.0 2.7 3 0 0 3 3 3 0 Tup N-terminal ArdA PF07275.6 GAM21344.1 - 0.036 14.3 0.5 0.066 13.4 0.3 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Viral_Beta_CD PF04530.7 GAM21344.1 - 0.076 13.1 0.3 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family Fib_alpha PF08702.5 GAM21344.1 - 0.087 12.9 1.4 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3154 PF11351.3 GAM21344.1 - 0.12 12.0 0.1 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) TPPK_C PF12555.3 GAM21344.1 - 0.44 10.3 5.3 0.69 9.6 3.7 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Use1 PF09753.4 GAM21344.1 - 1.6 8.0 7.5 1.5 8.2 0.1 2.8 1 1 0 1 1 1 0 Membrane fusion protein Use1 Atx10homo_assoc PF09759.4 GAM21345.1 - 0.0073 16.0 0.5 0.63 9.8 0.1 3.0 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Ribosomal_60s PF00428.14 GAM21345.1 - 8.4 6.8 14.2 1.4 9.3 0.3 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein RhoGAP PF00620.22 GAM21346.1 - 1.9e-40 137.9 0.6 3e-40 137.3 0.4 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 GAM21346.1 - 0.032 13.0 0.1 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Vac14_Fab1_bd PF12755.2 GAM21346.1 - 0.18 12.2 0.2 26 5.2 0.1 2.6 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Methyltransf_11 PF08241.7 GAM21347.1 - 2.3e-14 53.6 0.0 4.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM21347.1 - 3.9e-10 39.5 0.0 4.8e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM21347.1 - 1.5e-08 35.1 0.0 2.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM21347.1 - 4.1e-07 30.3 0.0 1.9e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM21347.1 - 8.8e-07 29.3 0.0 1.4e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM21347.1 - 2.1e-06 27.0 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAM21347.1 - 7.1e-06 25.8 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAM21347.1 - 0.0056 16.3 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 1 Hypothetical methyltransferase NodS PF05401.6 GAM21347.1 - 0.024 14.0 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_29 PF03141.11 GAM21347.1 - 0.025 12.9 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 GAM21347.1 - 0.042 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GHMP_kinases_N PF00288.21 GAM21348.1 - 2.6e-13 49.8 2.6 5.1e-13 48.8 1.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 GAM21348.1 - 0.00078 19.6 0.0 0.0027 17.8 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal CEP76-C2 PF15627.1 GAM21348.1 - 0.078 12.4 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 CEP76 C2 domain Alpha-mann_mid PF09261.6 GAM21349.1 - 6e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38 PF01074.17 GAM21349.1 - 2.5e-14 53.1 0.1 7.2e-14 51.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM21349.1 - 0.00013 20.8 0.0 0.067 11.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Clat_adaptor_s PF01217.15 GAM21350.1 - 2.3e-35 121.3 4.6 2.7e-35 121.1 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TMEM154 PF15102.1 GAM21351.1 - 0.95 9.1 7.3 2.2 7.9 5.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family adh_short PF00106.20 GAM21352.1 - 2.6e-24 85.9 0.1 3.8e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM21352.1 - 4.3e-13 49.6 0.0 9e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM21352.1 - 1e-07 31.3 0.0 3.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM21352.1 - 7.3e-05 22.5 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 GAM21352.1 - 0.01 16.2 0.7 0.034 14.5 0.5 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAM21352.1 - 0.026 14.1 0.2 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Toxin_50 PF15530.1 GAM21352.1 - 0.03 14.2 0.4 0.13 12.1 0.0 2.1 2 1 0 2 2 2 0 Putative toxin 50 Shikimate_DH PF01488.15 GAM21352.1 - 0.038 14.0 0.5 0.11 12.5 0.2 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Radical_SAM_N PF08497.5 GAM21352.1 - 0.046 12.6 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal DUF2656 PF10847.3 GAM21353.1 - 0.012 15.4 0.1 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2656) Phage_Gp14 PF10666.4 GAM21353.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp14 APC_CDC26 PF10471.4 GAM21353.1 - 2.9 8.6 10.2 0.32 11.7 2.5 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Ank_2 PF12796.2 GAM21354.1 - 2.9e-47 158.9 0.2 2.8e-14 53.2 0.1 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM21354.1 - 2.5e-35 118.5 0.7 1.5e-06 27.6 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 GAM21354.1 - 7.8e-32 108.5 2.9 6e-08 32.6 0.0 6.9 3 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM21354.1 - 2.5e-31 107.4 3.0 9e-06 26.0 0.0 7.7 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21354.1 - 2.7e-27 92.0 0.1 0.0012 18.8 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat GRP PF07172.6 GAM21354.1 - 0.75 10.3 10.8 1.9 8.9 7.5 1.7 1 0 0 1 1 1 0 Glycine rich protein family Aldedh PF00171.17 GAM21356.1 - 6e-135 450.1 0.0 7.3e-135 449.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM21356.1 - 0.0033 16.2 0.0 0.0095 14.6 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Transgly_assoc PF04226.8 GAM21356.1 - 0.02 14.9 0.3 0.057 13.4 0.2 1.7 1 0 0 1 1 1 0 Transglycosylase associated protein Act-Frag_cataly PF09192.5 GAM21357.1 - 1.9e-48 164.8 1.1 2.4e-48 164.5 0.8 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic Afi1 PF07792.7 GAM21359.1 - 4.2e-43 146.8 2.0 4.2e-43 146.8 1.4 2.8 2 1 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 GAM21359.1 - 2.1e-35 120.8 0.0 1.3e-34 118.2 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 GAM21359.1 - 9.9e-11 40.7 5.0 3.5e-05 22.4 0.0 4.0 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.4 GAM21359.1 - 4.1e-08 32.8 4.1 2.5e-05 23.6 0.0 3.7 3 1 1 4 4 4 2 Uncharacterized conserved protein (DUF2347) PRELI PF04707.9 GAM21359.1 - 0.029 13.9 2.2 0.057 12.9 1.5 1.5 1 0 0 1 1 1 0 PRELI-like family DUF2894 PF11445.3 GAM21359.1 - 0.09 13.0 0.1 0.09 13.0 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) Glycolytic PF00274.14 GAM21360.1 - 4.5e-162 538.3 0.0 5e-162 538.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RNase_H2-Ydr279 PF09468.5 GAM21361.1 - 4.1e-39 134.5 5.5 4.1e-39 134.5 3.8 1.9 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 GAM21361.1 - 0.52 8.2 13.3 0.82 7.6 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CD99L2 PF12301.3 GAM21361.1 - 0.89 9.2 15.6 2 8.0 10.8 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 Nop14 PF04147.7 GAM21361.1 - 0.92 7.3 16.2 1.6 6.5 11.2 1.3 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 GAM21361.1 - 1.3 6.7 14.8 1.8 6.2 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SURF2 PF05477.6 GAM21361.1 - 8.4 5.4 14.6 18 4.3 10.1 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF748 PF05359.6 GAM21362.1 - 0.1 12.5 0.0 0.96 9.4 0.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF748) COG2 PF06148.6 GAM21363.1 - 4.5e-25 88.0 1.2 5.6e-25 87.7 0.8 1.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 GAM21363.1 - 7.4e-05 22.5 0.5 0.0001 22.0 0.0 1.5 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 GAM21363.1 - 0.046 13.6 0.1 0.046 13.6 0.1 1.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3510 PF12022.3 GAM21364.1 - 9.9e-27 93.5 10.6 1.2e-26 93.2 3.8 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3510) DUF3439 PF11921.3 GAM21364.1 - 0.41 10.4 7.6 1.5 8.6 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RabGAP-TBC PF00566.13 GAM21365.1 - 1.8e-51 174.6 7.3 1.8e-51 174.6 5.0 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Dicty_REP PF05086.7 GAM21365.1 - 0.031 12.0 15.4 0.058 11.1 10.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M4 PF01447.13 GAM21365.1 - 0.098 12.7 9.2 0.28 11.2 6.4 1.7 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain PRAI PF00697.17 GAM21365.1 - 0.35 10.3 5.8 0.062 12.8 0.4 2.1 2 0 0 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3439 PF11921.3 GAM21365.1 - 0.84 9.4 16.1 2.1 8.1 11.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM21365.1 - 0.88 9.3 29.0 1.7 8.4 20.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.8 GAM21365.1 - 0.99 7.4 8.0 1.6 6.8 5.5 1.2 1 0 0 1 1 1 0 Menin DUF1117 PF06547.7 GAM21365.1 - 1.9 8.6 5.9 0.66 10.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Rad60-SLD PF11976.3 GAM21366.1 - 7.5e-08 31.9 0.0 9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM21366.1 - 0.00029 20.1 0.1 0.00034 19.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 GAM21366.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD FAD_syn PF06574.7 GAM21367.1 - 0.044 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD synthetase CTP_transf_2 PF01467.21 GAM21367.1 - 0.063 13.3 0.3 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Cytidylyltransferase Mito_carr PF00153.22 GAM21369.1 - 9.7e-71 233.5 1.7 1.8e-24 85.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Nucleo_P87 PF07267.6 GAM21370.1 - 2.5e-05 23.1 7.3 3.4e-05 22.7 5.1 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 IER PF05760.7 GAM21370.1 - 0.04 13.8 11.7 0.065 13.1 8.1 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) AMP-binding PF00501.23 GAM21371.1 - 4.4e-58 196.6 0.0 6.7e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM21371.1 - 1.2e-50 171.7 0.0 2.2e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM21371.1 - 1.6e-09 37.5 0.1 7.3e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM21371.1 - 6.1e-08 31.6 1.1 1.2e-06 27.5 0.3 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 GAM21371.1 - 3.7e-05 23.8 0.2 0.00015 21.9 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 GAM21371.1 - 0.0017 18.3 0.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 2 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM21371.1 - 0.0032 16.4 0.0 0.025 13.4 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_7 PF13241.1 GAM21371.1 - 0.11 12.8 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding Ribosomal_L14e PF01929.12 GAM21372.1 - 6.1e-21 74.5 1.1 6.1e-21 74.5 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 GAM21372.1 - 0.0011 18.5 0.1 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 KOW motif Glyco_transf_22 PF03901.12 GAM21373.1 - 2.9e-48 164.9 29.0 3.7e-48 164.5 20.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GpcrRhopsn4 PF10192.4 GAM21374.1 - 2.7e-51 174.2 36.5 3.7e-51 173.7 25.3 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 GAM21374.1 - 8.1e-07 28.2 26.4 1.2e-06 27.7 18.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1772 PF08592.6 GAM21374.1 - 7.1 6.3 13.9 0.43 10.3 0.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) SAPS PF04499.10 GAM21375.1 - 3.5e-10 39.1 0.8 3.1e-06 26.1 0.0 5.2 4 2 0 4 4 4 3 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 GAM21375.1 - 1.1e-05 24.1 38.5 1.1e-05 24.1 26.7 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 WD40 PF00400.27 GAM21376.1 - 7.5e-37 123.9 6.7 2.9e-09 36.4 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 GAM21376.1 - 2.2e-26 91.7 9.8 4e-26 90.8 6.8 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 GAM21376.1 - 0.023 14.4 0.1 4.1 7.2 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF2040 PF09745.4 GAM21376.1 - 6.1 6.6 11.0 2.9 7.7 4.0 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 55 (DUF2040) FKBP_C PF00254.23 GAM21377.1 - 4.2e-33 113.2 0.1 1.3e-32 111.6 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nucleoplasmin PF03066.10 GAM21377.1 - 3.1e-12 46.2 0.6 5.3e-12 45.4 0.4 1.4 1 0 0 1 1 1 1 Nucleoplasmin YL1 PF05764.8 GAM21377.1 - 6.6e-06 25.9 7.8 8.7e-06 25.5 5.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 GAM21377.1 - 0.082 10.8 5.3 0.097 10.5 3.7 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 GAM21377.1 - 0.38 11.0 9.8 0.68 10.1 6.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 GAM21377.1 - 1.4 8.9 6.1 2.1 8.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Coiled PF05710.7 GAM21378.1 - 0.0042 17.5 1.7 0.0042 17.5 1.2 1.1 1 0 0 1 1 1 1 Coiled coil DNA_pol_A_exo1 PF01612.15 GAM21379.1 - 4.2e-44 150.1 0.1 8.1e-44 149.1 0.1 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 GAM21379.1 - 1.5e-17 63.0 0.0 3.7e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.7 GAM21379.1 - 6e-12 45.6 0.1 6e-12 45.6 0.1 2.2 2 0 0 2 2 2 1 PMC2NT (NUC016) domain RRM_6 PF14259.1 GAM21380.1 - 4e-09 36.3 0.0 6.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM21380.1 - 7.9e-09 35.0 0.0 1.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Actino_peptide PF14408.1 GAM21380.1 - 0.03 14.2 1.6 0.077 12.9 1.1 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes RRM_5 PF13893.1 GAM21380.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 GAM21381.1 - 6e-10 39.3 1.3 6e-10 39.3 0.9 2.2 2 1 0 2 2 2 1 PCI domain DUF2102 PF09875.4 GAM21382.1 - 0.14 11.7 1.4 0.34 10.4 0.3 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) TPR_1 PF00515.23 GAM21383.1 - 9.3e-61 199.1 23.2 1.9e-07 30.3 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21383.1 - 3.8e-50 163.7 19.2 1.3e-05 24.7 0.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21383.1 - 2.4e-46 155.2 17.7 1.9e-12 46.6 0.7 6.5 2 1 3 7 7 7 7 TPR repeat TPR_8 PF13181.1 GAM21383.1 - 8.8e-35 115.8 21.5 0.00049 19.6 1.3 9.7 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21383.1 - 9.4e-34 115.2 14.4 2.4e-07 30.6 0.1 6.4 3 1 4 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAM21383.1 - 7.8e-31 106.0 5.4 5.2e-07 30.1 0.0 6.7 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21383.1 - 4.1e-30 101.4 16.3 0.0035 17.4 0.0 11.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21383.1 - 4e-28 95.3 0.4 0.00016 22.0 0.2 9.0 3 3 6 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21383.1 - 1.6e-21 76.3 15.5 3.8e-06 27.1 0.0 6.5 4 1 2 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21383.1 - 2.1e-20 70.8 6.1 0.012 15.3 0.2 9.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAM21383.1 - 1.4e-19 69.0 16.0 0.048 14.1 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAM21383.1 - 2e-14 53.2 2.9 0.0087 15.8 0.0 6.4 2 2 4 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM21383.1 - 2.2e-10 40.5 19.7 9.7e-05 22.4 2.1 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAM21383.1 - 1e-07 31.2 8.1 0.0013 17.8 4.1 3.4 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM21383.1 - 1.8e-05 24.7 1.0 2.9 8.0 0.0 6.1 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 GAM21383.1 - 0.0036 17.2 6.2 4.9 7.0 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.3 GAM21384.1 - 8.1 6.3 33.0 0.051 13.5 7.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myosin_head PF00063.16 GAM21385.1 - 5e-270 897.3 1.4 5e-270 897.3 1.0 4.1 4 2 1 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 GAM21385.1 - 4.2e-104 349.0 475.1 6e-38 130.1 87.9 5.9 1 1 4 5 5 5 5 Myosin tail Filament PF00038.16 GAM21385.1 - 3.3e-15 56.3 290.6 7.2e-06 25.6 12.8 12.5 1 1 10 11 11 11 8 Intermediate filament protein Myosin_N PF02736.14 GAM21385.1 - 1.3e-11 43.9 0.5 4.2e-11 42.3 0.4 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 GAM21385.1 - 0.00036 19.9 3.1 0.0039 16.7 0.5 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif DivIC PF04977.10 GAM21385.1 - 0.0016 17.8 7.2 0.0016 17.8 5.0 22.4 8 5 15 24 24 24 1 Septum formation initiator Cortex-I_coil PF09304.5 GAM21385.1 - 0.0065 16.5 17.2 0.0065 16.5 11.9 17.3 2 1 19 22 22 22 3 Cortexillin I, coiled coil AAA_19 PF13245.1 GAM21385.1 - 0.051 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 GAM21386.1 - 3.1e-31 108.5 0.1 3.1e-31 108.5 0.0 1.9 2 1 0 2 2 2 1 ABC transporter SbcCD_C PF13558.1 GAM21386.1 - 0.00055 19.8 0.1 0.01 15.6 0.1 2.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAM21386.1 - 0.027 13.6 0.1 0.067 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM21386.1 - 0.07 13.9 0.1 0.21 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAM21386.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 GAM21386.1 - 0.37 10.1 2.7 0.64 9.3 0.1 2.6 3 1 0 3 3 3 0 AAA domain Myb_DNA-binding PF00249.26 GAM21387.1 - 9.4e-16 57.6 3.9 5.2e-06 26.4 0.0 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM21387.1 - 1.8e-14 53.5 7.8 5e-05 23.3 0.0 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Mus7 PF09462.5 GAM21388.1 - 0.002 17.0 0.7 0.002 17.0 0.5 2.0 2 0 0 2 2 2 1 Mus7/MMS22 family DUF2457 PF10446.4 GAM21388.1 - 0.66 8.6 11.7 1.3 7.6 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SID-1_RNA_chan PF13965.1 GAM21388.1 - 3.9 5.5 9.4 1.1 7.2 1.6 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Methyltrans_RNA PF04452.9 GAM21389.1 - 3.4e-44 150.6 0.0 4.4e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase UL40 PF10682.4 GAM21389.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 RhoGAP PF00620.22 GAM21390.1 - 4.6e-49 165.9 1.6 5e-49 165.8 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 GAM21390.1 - 3.3e-11 43.3 1.7 5.9e-11 42.4 0.1 2.3 2 0 0 2 2 2 1 PH domain SH3_2 PF07653.12 GAM21390.1 - 2.6e-09 36.4 0.0 4.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAM21390.1 - 3e-09 36.3 0.3 6e-09 35.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM21390.1 - 4e-08 32.5 0.1 7.4e-08 31.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.1 GAM21390.1 - 4.4e-06 26.9 0.7 4.4e-06 26.9 0.5 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain MMPL PF03176.10 GAM21390.1 - 0.035 12.8 1.6 0.055 12.1 1.1 1.3 1 0 0 1 1 1 0 MMPL family V_ATPase_I PF01496.14 GAM21390.1 - 5 4.8 10.9 7.9 4.2 7.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TIG PF01833.19 GAM21391.1 - 9.6e-11 41.5 6.3 1.5e-06 28.0 0.9 4.1 3 1 1 4 4 4 2 IPT/TIG domain EGF_2 PF07974.8 GAM21391.1 - 0.0073 16.4 11.5 0.02 15.0 8.0 1.8 1 0 0 1 1 1 1 EGF-like domain EGF_CA PF07645.10 GAM21391.1 - 2.4 8.1 10.0 9.4 6.3 6.9 2.0 1 0 0 1 1 1 0 Calcium-binding EGF domain Maf PF02545.9 GAM21392.1 - 7.2e-32 110.0 0.1 9.4e-32 109.7 0.1 1.1 1 0 0 1 1 1 1 Maf-like protein FNIP PF05725.7 GAM21393.1 - 3.6e-76 250.8 31.3 1.5e-13 50.4 0.1 11.8 7 3 6 13 13 13 13 FNIP Repeat Gas_vesicle PF00741.13 GAM21394.1 - 0.023 14.5 2.9 0.035 13.9 2.0 1.2 1 0 0 1 1 1 0 Gas vesicle protein Coiled PF05710.7 GAM21394.1 - 0.11 13.0 2.6 0.12 12.8 1.8 1.3 1 1 0 1 1 1 0 Coiled coil IBR PF01485.16 GAM21395.1 - 5.7e-21 74.1 23.4 7e-13 48.2 2.9 4.4 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 GAM21395.1 - 5.2e-06 26.1 10.2 5.2e-06 26.1 7.1 4.3 2 1 2 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 GAM21395.1 - 0.00083 19.0 10.6 0.00083 19.0 7.3 3.7 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM21395.1 - 0.004 16.7 8.7 0.004 16.7 6.0 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM21395.1 - 0.007 16.3 10.3 0.007 16.3 7.1 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Merozoite_SPAM PF07133.6 GAM21395.1 - 0.037 13.9 13.4 0.095 12.5 9.3 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) ABC2_membrane_3 PF12698.2 GAM21395.1 - 3.8 6.4 5.6 7.4 5.4 3.9 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Dus PF01207.12 GAM21396.1 - 7.2e-71 238.5 0.1 9.7e-71 238.1 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 GAM21396.1 - 2.5e-05 23.6 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 GAM21396.1 - 0.0058 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Med20 PF08612.6 GAM21396.1 - 0.0093 15.1 0.5 0.031 13.4 0.0 1.9 2 0 0 2 2 2 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DHO_dh PF01180.16 GAM21396.1 - 0.019 13.9 0.0 0.053 12.4 0.0 1.7 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase SOR_SNZ PF01680.12 GAM21396.1 - 0.066 12.8 0.3 2.6 7.5 0.0 2.6 3 0 0 3 3 3 0 SOR/SNZ family G3P_antiterm PF04309.7 GAM21396.1 - 0.13 11.2 0.6 0.34 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DUF996 PF06195.8 GAM21397.1 - 0.0079 16.1 2.5 0.0079 16.1 1.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF996) SUR7 PF06687.7 GAM21397.1 - 0.031 13.8 7.1 0.067 12.7 2.9 2.0 2 0 0 2 2 2 0 SUR7/PalI family DUF1240 PF06836.7 GAM21397.1 - 0.36 11.0 8.1 0.063 13.4 2.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) DUF4131 PF13567.1 GAM21397.1 - 0.62 9.4 6.0 0.28 10.5 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4064 PF13273.1 GAM21397.1 - 0.74 9.9 7.7 0.89 9.6 3.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Peptidase_A24 PF01478.13 GAM21397.1 - 1.3 9.2 5.9 2.5 8.2 4.1 1.4 1 1 0 1 1 1 0 Type IV leader peptidase family DUF202 PF02656.10 GAM21397.1 - 4.1 7.7 8.7 2.1 8.6 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2207 PF09972.4 GAM21397.1 - 4.1 5.8 7.0 15 4.0 3.5 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1240 PF06836.7 GAM21398.1 - 4.1 7.6 8.6 0.52 10.5 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) WD40 PF00400.27 GAM21400.1 - 6.9e-21 73.3 13.6 2.5e-09 36.6 0.2 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM21400.1 - 6.5e-05 22.5 1.2 0.025 14.0 0.0 3.4 2 2 1 3 3 3 2 PQQ-like domain DUF3312 PF11768.3 GAM21400.1 - 0.0085 14.3 0.0 0.015 13.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) PAP2 PF01569.16 GAM21401.1 - 2.3e-21 75.7 2.1 2.3e-21 75.7 1.4 1.8 1 1 1 2 2 2 1 PAP2 superfamily ABG_transport PF03806.8 GAM21401.1 - 0.0059 14.6 2.5 0.012 13.6 1.8 1.5 1 1 0 1 1 1 1 AbgT putative transporter family 7TMR-DISM_7TM PF07695.6 GAM21401.1 - 7.5 6.1 14.6 9 5.9 7.0 2.6 1 1 1 2 2 2 0 7TM diverse intracellular signalling PfkB PF00294.19 GAM21402.1 - 3.8e-12 45.9 0.0 6.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase EMP24_GP25L PF01105.19 GAM21403.1 - 1.1e-48 165.4 1.6 1.3e-48 165.1 1.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NEP PF10167.4 GAM21403.1 - 0.095 12.4 0.2 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein zf-C2H2 PF00096.21 GAM21404.1 - 0.0013 18.9 10.9 0.1 12.9 2.9 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type CpXC PF14353.1 GAM21404.1 - 0.018 14.9 1.4 0.018 14.9 1.0 2.7 2 1 0 2 2 2 0 CpXC protein Cellulose_synt PF03552.9 GAM21404.1 - 0.13 10.5 3.2 0.13 10.4 2.2 1.1 1 0 0 1 1 1 0 Cellulose synthase zf-met PF12874.2 GAM21404.1 - 0.14 12.3 6.3 0.97 9.7 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pex14_N PF04695.8 GAM21404.1 - 0.17 11.9 5.0 0.22 11.5 3.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LMBR1 PF04791.11 GAM21404.1 - 0.3 9.6 2.4 0.31 9.5 1.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_4 PF13894.1 GAM21404.1 - 0.41 11.0 19.8 1.4 9.4 4.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Ycf1 PF05758.7 GAM21404.1 - 0.7 7.5 7.4 0.81 7.3 5.1 1.0 1 0 0 1 1 1 0 Ycf1 zf-C2H2_jaz PF12171.3 GAM21404.1 - 1.8 8.7 0.0 0.95 9.6 0.3 4.6 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding DEAD PF00270.24 GAM21405.1 - 6.9e-38 129.7 0.0 2.1e-36 124.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM21405.1 - 1.9e-28 98.1 0.0 4.7e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 GAM21405.1 - 0.0011 18.9 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SecA_DEAD PF07517.9 GAM21405.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain DUF1253 PF06862.7 GAM21405.1 - 0.1 10.9 0.0 0.51 8.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) zf-CCHC PF00098.18 GAM21405.1 - 5.5 7.1 9.4 0.44 10.5 2.1 2.1 2 0 0 2 2 2 0 Zinc knuckle TPT PF03151.11 GAM21406.1 - 3.2e-29 101.5 13.7 3.2e-29 101.5 9.5 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 GAM21406.1 - 1.9e-11 44.0 34.4 3.7e-07 30.2 5.7 3.3 1 1 3 4 4 4 2 EamA-like transporter family UAA PF08449.6 GAM21406.1 - 3.4e-09 36.0 29.1 7.3e-09 34.9 20.1 1.6 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 GAM21406.1 - 0.021 14.9 4.3 0.021 14.9 3.0 3.4 2 2 2 4 4 4 0 Multidrug resistance efflux transporter Methyltransf_12 PF08242.7 GAM21407.1 - 5.1e-11 42.9 0.2 1.7e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM21407.1 - 1.7e-09 37.9 3.3 6e-07 29.7 0.0 2.6 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAM21407.1 - 9.4e-09 35.8 0.0 2.9e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM21407.1 - 1.2e-08 34.7 6.2 4.8e-08 32.8 4.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM21407.1 - 2e-07 31.3 0.0 5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM21407.1 - 2.2e-07 30.4 0.0 3.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM21407.1 - 3.6e-07 29.8 0.2 1.1e-06 28.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 GAM21407.1 - 6.7e-05 22.2 0.1 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 GAM21407.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 GAM21407.1 - 0.0085 15.0 0.0 0.034 13.1 0.0 1.8 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family HAUS6_N PF14661.1 GAM21407.1 - 0.055 12.8 0.2 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GRAM PF02893.15 GAM21408.1 - 2.7e-08 33.2 0.1 1e-07 31.3 0.1 2.0 3 0 0 3 3 3 1 GRAM domain C2 PF00168.25 GAM21409.1 - 4e-05 23.3 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain GRAM PF02893.15 GAM21409.1 - 0.00016 21.1 0.2 0.00056 19.3 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Myosin_TH1 PF06017.8 GAM21410.1 - 3.5e-18 65.6 1.0 2.4e-17 62.9 0.4 2.0 1 1 1 2 2 2 1 Myosin tail SH3_1 PF00018.23 GAM21410.1 - 5.3e-17 60.9 0.1 9.7e-17 60.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM21410.1 - 5.2e-16 57.9 0.1 1e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM21410.1 - 2e-13 49.5 0.0 6.1e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Myosin_head PF00063.16 GAM21412.1 - 2.6e-259 861.9 3.0 4.2e-259 861.2 2.1 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_17 PF13207.1 GAM21412.1 - 0.0024 18.6 0.1 0.039 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM21412.1 - 0.0039 17.2 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 GAM21412.1 - 0.0053 17.0 0.1 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.7 GAM21412.1 - 0.0091 15.3 0.2 0.28 10.4 0.0 2.6 3 0 0 3 3 3 1 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 GAM21412.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 GAM21412.1 - 0.012 15.7 0.0 0.04 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM21412.1 - 0.038 14.2 0.2 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 GAM21412.1 - 0.069 12.6 0.1 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 GAM21412.1 - 0.16 11.4 0.1 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAM21412.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 GAM21412.1 - 0.89 9.8 6.0 12 6.1 4.0 2.3 1 1 0 1 1 1 0 AAA domain PCMT PF01135.14 GAM21413.1 - 1.4e-27 96.6 0.0 2.3e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BTB PF00651.26 GAM21413.1 - 4e-25 87.9 6.3 2e-15 56.7 0.1 3.1 2 1 1 3 3 3 2 BTB/POZ domain DOT1 PF08123.8 GAM21413.1 - 1.3e-05 24.6 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PH_3 PF14593.1 GAM21414.1 - 3.7e-12 46.0 0.0 1.2e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH PF00169.24 GAM21414.1 - 2.2e-07 31.0 0.1 7e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM21414.1 - 1.6e-05 25.1 2.6 1.8e-05 24.9 0.1 2.5 2 1 1 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.1 GAM21414.1 - 0.0034 17.4 0.0 0.0099 15.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 GAM21414.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF605 PF04652.11 GAM21414.1 - 3.9 6.7 25.7 4.2 6.6 5.9 2.3 2 0 0 2 2 2 0 Vta1 like DUF641 PF04859.7 GAM21414.1 - 6.4 6.5 25.2 0.087 12.5 3.3 4.5 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) DDHD PF02862.12 GAM21415.1 - 7e-31 107.7 1.0 3.4e-23 82.6 0.0 2.3 2 0 0 2 2 2 2 DDHD domain Abhydrolase_8 PF06259.7 GAM21415.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF962 PF06127.6 GAM21416.1 - 1.2e-33 114.8 0.7 1.4e-33 114.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Ribosomal_S21e PF01249.13 GAM21418.1 - 3.9e-38 129.2 0.0 4.2e-38 129.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Rep_fac_C PF08542.6 GAM21419.1 - 3.4e-23 81.4 1.3 5.8e-23 80.6 0.2 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAM21419.1 - 1.5e-11 44.2 0.0 2.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAM21419.1 - 3.3e-05 24.0 0.0 7.9e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM21419.1 - 6.1e-05 23.0 0.0 0.0037 17.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 GAM21419.1 - 0.00018 20.3 0.0 0.00033 19.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAM21419.1 - 0.0004 20.5 0.0 0.00089 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAM21419.1 - 0.0016 17.2 0.1 0.6 8.7 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus RuvB_N PF05496.7 GAM21419.1 - 0.0016 17.5 0.1 1.2 8.0 0.0 3.0 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 GAM21419.1 - 0.0025 17.8 0.0 0.029 14.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 GAM21419.1 - 0.0034 16.3 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAM21419.1 - 0.011 15.4 0.1 0.044 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 GAM21419.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 GAM21419.1 - 0.045 13.3 0.1 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 GAM21419.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 GAM21419.1 - 0.069 12.6 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM21419.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.4 1 1 0 1 1 1 0 ABC transporter BBIP10 PF14777.1 GAM21419.1 - 0.21 10.9 1.2 9.3 5.7 0.0 2.8 3 0 0 3 3 3 0 Cilia BBSome complex subunit 10 His_Phos_1 PF00300.17 GAM21420.1 - 1e-23 84.1 0.2 6.7e-23 81.5 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Acyl-CoA_dh_1 PF00441.19 GAM21421.1 - 4.2e-47 160.0 0.7 6.1e-47 159.4 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM21421.1 - 1.3e-24 86.8 0.0 2.4e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM21421.1 - 3.6e-22 77.6 0.0 1.2e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM21421.1 - 1.3e-20 73.9 0.1 2.3e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Patatin PF01734.17 GAM21422.1 - 1.7e-18 67.2 0.1 5.6e-18 65.6 0.1 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase Telomere_reg-2 PF10193.4 GAM21423.1 - 4.5e-27 94.5 3.5 6.5e-27 94.0 0.3 2.7 2 1 0 2 2 2 1 Telomere length regulation protein DUF4042 PF13251.1 GAM21423.1 - 0.023 14.1 0.3 0.95 8.8 0.0 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4042) DUF2457 PF10446.4 GAM21423.1 - 7.7 5.1 16.6 13 4.3 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Methyltransf_26 PF13659.1 GAM21424.1 - 7.9e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM21424.1 - 3.5e-09 36.2 0.0 6.9e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 GAM21424.1 - 3.4e-08 32.9 0.0 6.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAM21424.1 - 2.9e-07 30.1 0.0 1.5e-06 27.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM21424.1 - 1.8e-06 28.5 0.0 3.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM21424.1 - 6.6e-05 23.3 0.4 0.00046 20.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM21424.1 - 0.00044 20.5 0.0 0.0018 18.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM21424.1 - 0.00099 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM21424.1 - 0.0022 18.4 0.0 0.0073 16.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain RrnaAD PF00398.15 GAM21424.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 GAM21424.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 GAM21424.1 - 0.028 13.4 0.3 0.07 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_16 PF10294.4 GAM21424.1 - 0.053 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_10 PF05971.7 GAM21424.1 - 0.069 12.2 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF890) Methyltransf_15 PF09445.5 GAM21424.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 GAM21424.1 - 0.092 12.4 0.3 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain LRR_6 PF13516.1 GAM21425.1 - 4.3e-47 152.8 69.4 1.5e-05 24.5 0.4 18.8 19 0 0 19 19 19 13 Leucine Rich repeat LRR_4 PF12799.2 GAM21425.1 - 2.2e-07 30.3 73.0 0.0033 17.0 0.7 11.2 8 3 3 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM21425.1 - 4.9e-06 26.2 64.7 0.007 16.1 3.4 10.0 6 3 4 11 11 11 6 Leucine rich repeat LRR_1 PF00560.28 GAM21425.1 - 9.8e-06 24.9 50.3 0.6 10.3 0.1 15.7 18 1 0 18 18 18 2 Leucine Rich Repeat F-box-like PF12937.2 GAM21425.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_7 PF13504.1 GAM21425.1 - 1.9 9.0 37.3 1.1 9.7 0.1 12.0 12 1 1 13 13 13 0 Leucine rich repeat GSH_synthase PF03199.10 GAM21426.1 - 0.91 9.6 6.3 0.18 11.9 0.7 2.0 2 0 0 2 2 2 0 Eukaryotic glutathione synthase GATase_4 PF13230.1 GAM21427.1 - 4.6e-17 61.5 0.1 6.6e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 GAM21427.1 - 2.7e-13 50.0 0.1 4.3e-12 46.1 0.0 2.4 2 1 1 3 3 3 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAM21427.1 - 7.4e-05 21.6 0.1 0.00014 20.7 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II CRAL_TRIO PF00650.15 GAM21428.1 - 1.2e-20 73.6 0.0 2e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 GAM21428.1 - 1.7e-08 34.5 0.1 2.7e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Helicase_C_2 PF13307.1 GAM21429.1 - 3.2e-54 183.3 0.0 7.6e-54 182.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 GAM21429.1 - 3.5e-45 153.5 0.4 5.8e-45 152.8 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 GAM21429.1 - 8.2e-07 29.0 1.3 0.0011 18.8 0.1 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM21429.1 - 0.00031 20.2 0.0 0.029 13.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 GAM21429.1 - 0.14 11.3 0.8 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.12 GAM21430.1 - 1.8e-83 279.7 0.1 2e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAM21430.1 - 1.2e-05 26.1 0.0 2.6e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 GAM21430.1 - 0.00013 21.4 0.0 0.00096 18.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 GAM21430.1 - 0.00018 21.1 0.0 0.00038 20.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM21430.1 - 0.00027 20.4 0.0 0.00051 19.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM21430.1 - 0.0013 18.9 0.0 0.0035 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM21430.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 GAM21430.1 - 0.026 14.2 0.0 0.94 9.1 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 GAM21430.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 GAM21430.1 - 0.042 13.9 0.0 0.13 12.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 GAM21430.1 - 0.043 13.2 0.1 5.2 6.5 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 GAM21430.1 - 0.045 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 GAM21430.1 - 0.06 13.6 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 GAM21430.1 - 0.066 12.4 0.0 0.5 9.5 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SMC_N PF02463.14 GAM21430.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 GAM21430.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3368 PF11848.3 GAM21430.1 - 0.11 12.0 0.0 4.3 6.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) AAA PF00004.24 GAM21430.1 - 0.13 12.4 0.0 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM21430.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 GAM21430.1 - 0.15 10.8 0.0 0.31 9.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein TPR_20 PF14561.1 GAM21431.1 - 2e-20 72.6 4.8 3.1e-20 72.0 0.2 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Thioredoxin PF00085.15 GAM21431.1 - 1.5e-17 63.1 0.1 7e-17 61.0 0.0 2.1 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 GAM21431.1 - 1.3e-06 28.3 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_19 PF14559.1 GAM21431.1 - 7.6e-06 26.1 2.1 0.0025 18.1 0.8 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21431.1 - 0.00071 19.9 1.1 0.41 11.4 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Thioredoxin_2 PF13098.1 GAM21431.1 - 0.0014 18.8 0.1 0.0076 16.4 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TPR_16 PF13432.1 GAM21431.1 - 0.0015 19.1 0.8 1.9 9.2 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Thioredoxin_8 PF13905.1 GAM21431.1 - 0.016 15.3 0.1 8.2 6.6 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like TPR_2 PF07719.12 GAM21431.1 - 0.077 12.9 1.4 14 5.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21431.1 - 0.082 12.5 0.8 2 8.1 0.1 2.4 2 0 0 2 2 2 0 TPR repeat Dicty_CTDC PF00526.13 GAM21432.1 - 1e-09 38.0 184.7 1.4e-05 24.7 5.3 13.4 12 2 1 13 13 13 9 Dictyostelium (slime mold) repeat Phytochelatin PF05023.9 GAM21435.1 - 2.9e-86 287.8 0.0 5e-86 287.0 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Phytochelatin_C PF09328.5 GAM21435.1 - 0.0001 21.9 0.1 0.022 14.2 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1984) Peptidase_C39_2 PF13529.1 GAM21435.1 - 0.02 15.2 0.0 0.51 10.6 0.0 2.7 2 0 0 2 2 2 0 Peptidase_C39 like family E1-E2_ATPase PF00122.15 GAM21436.1 - 1.6 7.6 8.3 1.8 7.5 5.7 1.0 1 0 0 1 1 1 0 E1-E2 ATPase Tic20 PF09685.5 GAM21436.1 - 5.1 7.1 8.2 5.6 6.9 5.7 1.2 1 0 0 1 1 1 0 Tic20-like protein VirB3 PF05101.8 GAM21436.1 - 7.3 6.6 7.9 9.3 6.3 5.5 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Syja_N PF02383.13 GAM21437.1 - 1.8e-87 293.1 0.6 3.7e-87 292.0 0.4 1.6 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 GAM21437.1 - 2.3e-24 84.9 0.2 4.4e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Inositol phosphatase Sigma70_ner PF04546.8 GAM21437.1 - 0.35 10.4 6.7 0.44 10.1 4.0 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region BTV_NS2 PF04514.7 GAM21437.1 - 2.1 7.1 7.9 3.5 6.4 5.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RRN3 PF05327.6 GAM21437.1 - 2.6 6.0 11.3 4.2 5.3 7.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C2H2_4 PF13894.1 GAM21438.1 - 0.74 10.2 3.9 0.6 10.5 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM21438.1 - 2.5 8.6 5.7 0.45 10.9 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type PPTA PF01239.17 GAM21439.1 - 1.2e-45 151.0 11.5 1.6e-09 36.6 0.3 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat HECT_2 PF09814.4 GAM21440.1 - 1.3e-10 40.5 1.3 1.5e-10 40.3 0.9 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding EMP24_GP25L PF01105.19 GAM21440.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Securin PF04856.8 GAM21440.1 - 0.098 12.3 1.0 0.32 10.6 0.8 1.6 1 1 1 2 2 2 0 Securin sister-chromatid separation inhibitor zf-RING_2 PF13639.1 GAM21441.1 - 2e-10 40.3 10.0 2e-10 40.3 6.9 3.6 3 0 0 3 3 3 1 Ring finger domain ZZ PF00569.12 GAM21441.1 - 6.7e-10 38.3 25.7 2.7e-08 33.2 7.7 5.1 5 1 0 5 5 5 2 Zinc finger, ZZ type zf-rbx1 PF12678.2 GAM21441.1 - 2.3e-07 30.8 7.6 2.3e-07 30.8 5.3 3.6 4 0 0 4 4 4 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM21441.1 - 0.00031 20.5 6.9 0.00031 20.5 4.8 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 GAM21441.1 - 0.00096 19.1 11.4 0.00096 19.1 7.9 4.6 5 1 0 5 5 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM21441.1 - 0.013 15.2 8.7 0.013 15.2 6.1 4.4 4 1 0 4 4 4 0 zinc-RING finger domain zinc_ribbon_4 PF13717.1 GAM21441.1 - 0.018 14.6 0.4 0.018 14.6 0.3 5.1 7 0 0 7 7 7 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 GAM21441.1 - 0.022 14.3 0.4 0.022 14.3 0.3 4.9 7 0 0 7 7 7 0 zinc-ribbon domain Mucin PF01456.12 GAM21441.1 - 0.43 10.3 28.5 0.28 10.9 5.3 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein HsbA PF12296.3 GAM21441.1 - 4.3 7.2 9.9 0.13 12.1 1.6 2.0 2 0 0 2 2 2 0 Hydrophobic surface binding protein A CwfJ_C_1 PF04677.10 GAM21443.1 - 1.9e-31 108.2 2.7 3.6e-31 107.3 1.9 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 GAM21443.1 - 1.3e-20 73.6 0.0 1.3e-20 73.6 0.0 3.5 4 0 0 4 4 4 1 Protein similar to CwfJ C-terminus 2 polyprenyl_synt PF00348.12 GAM21444.1 - 7.1e-65 218.4 0.0 9.1e-65 218.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ELMO_CED12 PF04727.8 GAM21445.1 - 3.9e-39 133.9 0.0 7.6e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family Ank_2 PF12796.2 GAM21445.1 - 6.4e-24 84.1 1.7 5e-17 62.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM21445.1 - 1.3e-23 81.5 1.3 4.4e-06 26.2 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 GAM21445.1 - 9.9e-17 59.3 1.0 0.0018 18.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM21445.1 - 1.3e-15 57.4 4.2 1.9e-09 37.7 0.0 5.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM21445.1 - 3.2e-13 49.4 3.9 8.9e-06 25.7 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DUF3361 PF11841.3 GAM21445.1 - 3.1e-06 27.0 4.3 3.1e-06 27.0 3.0 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF3361) F-box-like PF12937.2 GAM21446.1 - 6.8e-08 32.1 0.1 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM21446.1 - 2e-07 30.4 0.5 5.7e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 GAM21446.1 - 2.7e-05 23.8 0.2 0.00018 21.2 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat F-box-like_2 PF13013.1 GAM21446.1 - 0.0069 16.0 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like domain Peptidase_C1 PF00112.18 GAM21447.1 - 2e-70 237.0 4.5 2e-70 237.0 3.1 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM21447.1 - 3.1e-13 49.7 6.1 5.2e-13 49.0 4.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM21447.1 - 3.5e-08 32.4 1.4 1.4e-05 23.8 0.0 2.3 2 1 0 2 2 2 2 Peptidase C1-like family Notch PF00066.12 GAM21447.1 - 0.018 15.3 4.2 0.018 15.3 2.9 2.2 2 0 0 2 2 2 0 LNR domain Kinesin PF00225.18 GAM21448.1 - 4.7e-110 367.4 2.8 4.7e-110 367.4 1.9 2.5 2 1 1 3 3 3 1 Kinesin motor domain Totivirus_coat PF05518.6 GAM21448.1 - 0.97 7.1 2.6 1.5 6.5 1.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.27 GAM21449.1 - 9.8e-25 85.4 5.4 2.2e-06 27.3 0.2 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM21449.1 - 6.7e-05 22.6 0.0 0.00021 21.0 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 GAM21449.1 - 0.0073 15.9 0.1 3.6 7.3 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 GAM21449.1 - 0.032 12.5 0.0 0.059 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF218 PF02698.12 GAM21450.1 - 3.1e-29 101.4 0.0 2.1e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 DUF218 domain Mem_trans PF03547.13 GAM21450.1 - 0.0012 17.2 0.2 0.0012 17.2 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein Zip PF02535.17 GAM21450.1 - 0.0072 15.3 1.9 0.011 14.8 1.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.11 GAM21450.1 - 0.015 15.1 0.4 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 GAM21450.1 - 0.032 12.4 3.0 0.051 11.7 2.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RCR PF12273.3 GAM21450.1 - 0.13 12.7 4.0 0.34 11.4 2.8 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pex14_N PF04695.8 GAM21450.1 - 0.88 9.6 5.6 1.7 8.6 3.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltransf_12 PF08242.7 GAM21450.1 - 1.8 9.0 11.4 1.1e+02 3.3 0.0 3.9 2 2 1 3 3 3 0 Methyltransferase domain ETRAMP PF09716.5 GAM21450.1 - 1.9 8.4 4.4 11 6.0 3.1 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Chordopox_G3 PF06129.7 GAM21450.1 - 2 8.5 7.6 3.8 7.7 3.5 2.6 1 1 1 2 2 2 0 Chordopoxvirus G3 protein SPT2 PF08243.6 GAM21451.1 - 9.6e-11 42.0 30.0 9.6e-11 42.0 20.8 4.5 3 2 3 6 6 6 1 SPT2 chromatin protein HEAT_2 PF13646.1 GAM21452.1 - 0.00063 19.9 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 GAM21452.1 - 0.0012 18.7 0.2 24 5.3 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat BTB PF00651.26 GAM21452.1 - 0.046 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain Chromo PF00385.19 GAM21453.1 - 1.3e-09 37.6 0.3 3.1e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Coiled PF05710.7 GAM21454.1 - 1.2 9.6 9.9 2.5 8.6 6.9 1.6 1 1 0 1 1 1 0 Coiled coil Tmemb_14 PF03647.8 GAM21455.1 - 2.6e-21 75.8 15.5 2.8e-21 75.6 10.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CbiG_N PF11760.3 GAM21455.1 - 0.038 13.6 0.3 6.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal UbiA PF01040.13 GAM21455.1 - 0.13 11.4 11.4 0.16 11.1 7.9 1.0 1 0 0 1 1 1 0 UbiA prenyltransferase family MerC PF03203.9 GAM21455.1 - 9.1 6.6 8.8 3.2 8.1 3.7 1.7 1 1 0 1 1 1 0 MerC mercury resistance protein Ribosomal_60s PF00428.14 GAM21456.1 - 3.9e-20 72.0 14.2 4.6e-20 71.8 9.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 GAM21456.1 - 0.075 12.8 7.9 0.092 12.6 5.3 1.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective PepSY_2 PF13670.1 GAM21456.1 - 7.3 6.5 11.4 1.8 8.5 5.4 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Snf7 PF03357.16 GAM21457.1 - 3.2e-45 153.5 15.6 3.6e-45 153.4 10.8 1.0 1 0 0 1 1 1 1 Snf7 AIP3 PF03915.8 GAM21457.1 - 0.011 14.6 7.8 0.013 14.3 5.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Prefoldin PF02996.12 GAM21457.1 - 0.013 15.0 6.9 0.094 12.3 0.0 3.3 2 1 2 4 4 4 0 Prefoldin subunit OmpH PF03938.9 GAM21457.1 - 0.015 15.1 7.2 0.015 15.1 5.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1319 PF07028.6 GAM21457.1 - 0.026 14.6 0.8 0.026 14.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) ORF6C PF10552.4 GAM21457.1 - 0.067 12.9 6.2 0.5 10.1 0.7 2.4 2 0 0 2 2 2 0 ORF6C domain Pup PF05639.6 GAM21457.1 - 0.076 13.5 3.6 0.22 12.0 2.5 1.9 1 1 0 1 1 1 0 Pup-like protein TMF_DNA_bd PF12329.3 GAM21457.1 - 0.24 11.2 0.2 0.24 11.2 0.1 3.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 GAM21457.1 - 0.33 11.4 4.6 0.66 10.4 0.0 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF848 PF05852.6 GAM21457.1 - 0.47 10.3 7.2 1.3 8.8 4.2 2.0 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TSC22 PF01166.13 GAM21457.1 - 0.64 10.0 10.5 2.3 8.2 0.1 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family APG6 PF04111.7 GAM21457.1 - 0.93 8.4 11.2 1.3 7.9 7.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 GAM21457.1 - 1.4 8.4 13.5 4.6 6.7 3.0 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 GAM21457.1 - 2.6 6.3 10.1 2.4 6.4 5.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) YlqD PF11068.3 GAM21457.1 - 2.7 8.0 13.4 1.3 9.0 6.9 2.0 1 1 1 2 2 2 0 YlqD protein NuA4 PF09340.5 GAM21457.1 - 6 6.5 6.6 0.34 10.5 0.5 2.1 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 PfkB PF00294.19 GAM21458.1 - 2.2e-50 171.4 2.7 2.6e-50 171.2 1.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 GAM21458.1 - 0.00024 20.3 0.3 0.00046 19.4 0.2 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase AcetDehyd-dimer PF09290.6 GAM21458.1 - 0.078 12.8 0.1 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Sulfotransfer_1 PF00685.22 GAM21459.1 - 9.4e-18 64.4 0.1 1.3e-16 60.6 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase domain Glycos_transf_1 PF00534.15 GAM21459.1 - 1.3e-11 44.2 0.0 2.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM21459.1 - 4e-11 43.3 0.1 7.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Sulfotransfer_3 PF13469.1 GAM21459.1 - 1.5e-07 32.5 0.0 4.2e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Sulfotransferase family Glyco_transf_5 PF08323.6 GAM21459.1 - 0.00045 19.7 0.9 0.0016 17.9 0.1 2.2 2 0 0 2 2 2 1 Starch synthase catalytic domain Tox-PL PF15644.1 GAM21459.1 - 0.0018 18.9 0.1 0.006 17.2 0.1 1.9 1 0 0 1 1 1 1 Papain fold toxin 1 Glycos_transf_2 PF00535.21 GAM21459.1 - 0.0068 16.1 0.1 0.066 12.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2157 PF09925.4 GAM21460.1 - 1.4 8.4 6.9 0.18 11.4 1.4 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) p450 PF00067.17 GAM21461.1 - 1e-94 317.7 0.0 1.2e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydantoinase_B PF02538.9 GAM21461.1 - 0.074 11.2 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase TMEM164 PF14808.1 GAM21462.1 - 3e-21 75.7 11.3 3.8e-21 75.4 7.8 1.1 1 0 0 1 1 1 1 TMEM164 family Palm_thioest PF02089.10 GAM21463.1 - 2.4e-49 167.8 0.0 2.8e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.9 GAM21463.1 - 0.0052 16.0 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 GAM21463.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3997 PF13162.1 GAM21463.1 - 0.056 13.2 0.4 0.1 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) Abhydrolase_6 PF12697.2 GAM21463.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.17 GAM21464.1 - 2.8e-45 153.5 0.0 3.4e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21464.1 - 1.8e-18 67.1 0.0 2.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM21464.1 - 5e-08 32.3 0.0 6.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM21464.1 - 0.01 15.2 0.4 0.079 12.3 0.3 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HD PF01966.17 GAM21465.1 - 0.013 15.4 0.1 0.022 14.7 0.0 1.4 1 1 0 1 1 1 0 HD domain NRDE PF05742.7 GAM21466.1 - 1.2e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 NRDE protein IF-2B PF01008.12 GAM21467.1 - 4.1e-81 272.0 0.1 5.1e-81 271.7 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Rsbr_N PF08678.5 GAM21467.1 - 0.023 14.5 1.9 0.15 11.9 0.1 3.0 3 1 0 3 3 3 0 Rsbr N terminal DUF605 PF04652.11 GAM21467.1 - 5.8 6.2 33.0 4.1 6.7 21.7 1.5 2 0 0 2 2 2 0 Vta1 like FNIP PF05725.7 GAM21470.1 - 2.4e-41 139.4 10.4 5.1e-11 42.3 0.0 5.7 3 1 1 5 5 5 5 FNIP Repeat LRR_4 PF12799.2 GAM21470.1 - 0.083 12.5 2.4 0.2 11.3 0.1 2.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) RhoGAP PF00620.22 GAM21471.1 - 1.1e-23 83.5 0.1 4e-23 81.7 0.1 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAM21471.1 - 4.1e-16 58.9 0.5 4.1e-16 58.9 0.4 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2229 PF09989.4 GAM21471.1 - 0.24 10.8 10.2 0.024 14.1 2.8 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) APG5 PF04106.7 GAM21472.1 - 3.6e-58 196.2 1.5 7.9e-58 195.1 1.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 DUF912 PF06024.7 GAM21472.1 - 0.056 13.4 2.8 3.3 7.8 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDK2AP PF09806.4 GAM21472.1 - 9.3 6.4 9.6 14 5.8 0.4 2.4 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein ABC2_membrane PF01061.19 GAM21473.1 - 3.9e-33 114.3 29.2 3.9e-33 114.3 20.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 GAM21473.1 - 2.1e-21 76.6 0.0 3.9e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM21473.1 - 1.1e-09 38.6 0.0 0.0022 18.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAM21473.1 - 1.2e-05 24.6 0.0 9.9e-05 21.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 GAM21473.1 - 1.8e-05 24.2 0.0 0.0093 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAM21473.1 - 4.1e-05 22.8 0.1 0.14 11.2 0.1 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 GAM21473.1 - 0.00019 21.7 0.3 0.00042 20.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 GAM21473.1 - 0.00043 19.7 0.0 0.00096 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM21473.1 - 0.00053 20.7 0.0 0.001 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM21473.1 - 0.00064 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM21473.1 - 0.0015 18.6 0.0 0.006 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM21473.1 - 0.003 17.5 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAM21473.1 - 0.0038 16.1 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.14 GAM21473.1 - 0.0039 16.6 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 GAM21473.1 - 0.004 17.0 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM21473.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_23 PF13476.1 GAM21473.1 - 0.0064 16.8 0.1 0.012 15.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 GAM21473.1 - 0.0064 16.2 0.1 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 GAM21473.1 - 0.013 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 GAM21473.1 - 0.031 14.0 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 GAM21473.1 - 0.032 13.6 0.0 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 GAM21473.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAM21473.1 - 0.055 13.4 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 GAM21473.1 - 0.079 12.7 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA12 PF10443.4 GAM21473.1 - 0.14 10.5 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein SbcCD_C PF13558.1 GAM21473.1 - 0.15 12.0 0.0 0.75 9.7 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.2 GAM21473.1 - 0.17 10.9 39.6 0.11 11.5 23.7 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_30 PF13604.1 GAM21473.1 - 0.23 10.9 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.12 GAM21474.1 - 2.3e-52 177.6 0.1 2.2e-49 167.8 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 GAM21474.1 - 4.2e-45 153.9 0.1 1.2e-40 139.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.16 GAM21474.1 - 4.9e-28 96.6 0.1 3.4e-16 58.7 0.0 2.9 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Miro PF08477.8 GAM21474.1 - 3.5e-06 27.5 0.1 0.023 15.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 GAM21474.1 - 0.00093 18.6 0.2 0.46 9.8 0.0 2.3 2 0 0 2 2 2 2 Ras family AAA_28 PF13521.1 GAM21474.1 - 0.11 12.4 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.1 GAM21475.1 - 6.5e-10 38.5 11.2 2.1e-09 36.8 7.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM21475.1 - 0.0031 17.1 13.2 0.0081 15.8 8.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM21475.1 - 0.0032 17.0 13.4 0.024 14.2 9.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM21475.1 - 0.0058 16.6 13.1 0.0058 16.6 9.1 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM21475.1 - 0.42 10.4 12.5 0.62 9.9 7.7 2.2 2 0 0 2 2 2 0 Ring finger domain Minor_capsid_1 PF10665.4 GAM21476.1 - 0.018 14.8 0.1 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Minor capsid protein NICE-3 PF07406.6 GAM21477.1 - 0.0021 17.6 0.2 0.0021 17.6 0.1 1.6 2 0 0 2 2 2 1 NICE-3 protein DUF1180 PF06679.7 GAM21477.1 - 0.09 12.6 0.1 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PH PF00169.24 GAM21478.1 - 9e-20 70.8 0.0 9e-20 70.8 0.0 3.5 3 1 0 3 3 3 1 PH domain PTEN_C2 PF10409.4 GAM21478.1 - 8.4e-19 67.6 0.5 2.8e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.1 GAM21478.1 - 1.9e-09 37.7 1.8 1.9e-09 37.7 1.2 4.3 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.1 GAM21478.1 - 4.4e-08 33.0 0.0 1.2e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Y_phosphatase PF00102.22 GAM21478.1 - 3.1e-06 26.7 0.0 8.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PH_3 PF14593.1 GAM21478.1 - 3.5e-05 23.6 1.9 7.6e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 PH domain DSPc PF00782.15 GAM21478.1 - 4e-05 23.1 1.3 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAM21478.1 - 6.6e-05 23.2 0.1 0.00034 20.9 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family FtsJ PF01728.14 GAM21479.1 - 4.2e-10 39.9 0.0 6.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 GAM21479.1 - 0.025 15.1 0.0 0.083 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain WD40 PF00400.27 GAM21480.1 - 4.8e-06 26.2 0.0 0.0068 16.2 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 GAM21480.1 - 0.00022 20.4 0.5 0.0089 15.1 0.1 2.1 1 1 1 2 2 2 2 CPSF A subunit region DUF1513 PF07433.6 GAM21480.1 - 0.098 11.5 0.0 0.29 9.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) UPRTase PF14681.1 GAM21481.1 - 4.1e-81 271.1 0.0 4.7e-81 270.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 GAM21481.1 - 9.9e-07 28.5 0.0 2.2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Tup_N PF08581.5 GAM21482.1 - 1.8e-20 72.8 11.5 1.8e-20 72.8 8.0 3.3 3 0 0 3 3 3 1 Tup N-terminal DUF3450 PF11932.3 GAM21482.1 - 0.006 15.8 4.0 0.006 15.8 2.7 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3450) DUF605 PF04652.11 GAM21482.1 - 0.012 15.0 15.6 0.014 14.8 10.8 1.3 1 0 0 1 1 1 0 Vta1 like PhoU_div PF01865.11 GAM21482.1 - 0.044 12.9 0.1 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 PAT1 PF09770.4 GAM21482.1 - 1.9 6.6 43.4 2.2 6.3 30.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF87 PF01935.12 GAM21482.1 - 2 8.1 9.1 0.47 10.2 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Poxvirus_B22R_N PF13169.1 GAM21482.1 - 3.4 7.9 8.3 0.6 10.3 1.2 2.4 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal PXA PF02194.10 GAM21482.1 - 4.4 6.8 11.4 0.44 10.1 3.6 2.3 2 1 0 2 2 2 0 PXA domain Herpes_LMP2 PF07415.6 GAM21482.1 - 6.4 5.2 9.3 8.9 4.7 6.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Peptidase_C97 PF05903.9 GAM21483.1 - 6.9e-37 126.5 0.6 8.9e-37 126.1 0.4 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.1 GAM21483.1 - 0.096 11.8 0.2 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) HAT PF02184.11 GAM21484.1 - 5.4e-29 99.6 72.1 8.6e-09 35.0 0.3 15.5 15 1 0 15 15 15 8 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 GAM21484.1 - 6.8e-26 88.4 3.8 0.0084 16.6 0.0 10.0 3 3 8 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAM21484.1 - 6.9e-18 64.8 7.2 0.00049 20.7 0.1 7.9 6 2 2 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 GAM21484.1 - 2.5e-17 63.5 20.9 0.0003 20.6 0.2 5.9 3 2 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.1 GAM21484.1 - 1.1e-12 48.0 0.0 0.25 11.6 0.0 7.0 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21484.1 - 1.6e-08 33.8 5.2 0.38 10.7 0.1 7.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21484.1 - 3.7e-07 29.9 6.9 1.2 9.1 0.0 6.4 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21484.1 - 5.1e-07 29.3 1.8 0.009 16.1 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21484.1 - 2e-06 27.1 4.5 7.1 6.6 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21484.1 - 1e-05 25.0 5.4 0.095 12.3 0.0 5.2 5 1 0 5 5 5 1 TPR repeat TPR_6 PF13174.1 GAM21484.1 - 2.3e-05 24.5 15.3 8 7.1 0.0 9.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21484.1 - 7.2e-05 22.2 0.2 2.8 7.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21484.1 - 0.012 15.2 0.8 2 8.1 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 GAM21484.1 - 0.053 12.6 7.3 0.66 9.0 0.1 4.4 4 1 1 5 5 5 0 Soluble NSF attachment protein, SNAP Rubrerythrin PF02915.12 GAM21484.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.8 4 0 0 4 4 4 0 Rubrerythrin U3_assoc_6 PF08640.6 GAM21484.1 - 0.77 9.5 23.0 0.65 9.7 0.9 7.7 8 2 2 10 10 10 0 U3 small nucleolar RNA-associated protein 6 Scramblase PF03803.10 GAM21485.1 - 2.5e-30 105.2 0.7 3.7e-30 104.6 0.5 1.2 1 1 0 1 1 1 1 Scramblase Exo_endo_phos PF03372.18 GAM21486.1 - 4.3e-24 85.7 0.0 6.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2201_N PF13203.1 GAM21486.1 - 7.5 5.6 12.8 16 4.5 8.9 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain E1-E2_ATPase PF00122.15 GAM21487.1 - 1.6e-58 197.4 3.1 2.6e-58 196.7 2.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM21487.1 - 9.4e-40 136.0 2.3 9.4e-40 136.0 1.6 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM21487.1 - 2.8e-32 112.8 0.0 1.4e-31 110.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM21487.1 - 1.1e-24 86.1 0.6 3e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAM21487.1 - 2.1e-16 59.1 0.0 4.7e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM21487.1 - 1.4e-13 51.4 0.0 2.9e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM21487.1 - 3e-05 23.7 12.5 0.00062 19.4 0.2 3.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Exo70 PF03081.10 GAM21487.1 - 0.0037 16.0 0.0 0.0092 14.8 0.0 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF1400 PF07176.6 GAM21487.1 - 0.025 14.5 0.0 0.095 12.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) Abhydrolase_6 PF12697.2 GAM21488.1 - 8.9e-13 48.6 0.0 1.3e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM21488.1 - 1.2e-09 38.0 0.0 2.6e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM21488.1 - 5.9e-08 32.5 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 GAM21488.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF915 PF06028.6 GAM21488.1 - 0.035 13.2 0.0 0.15 11.1 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Mucin PF01456.12 GAM21489.1 - 0.00019 21.2 4.9 0.018 14.8 4.0 2.5 2 1 0 2 2 2 2 Mucin-like glycoprotein YbgS PF13985.1 GAM21489.1 - 0.22 11.4 9.9 0.37 10.7 6.8 1.3 1 0 0 1 1 1 0 YbgS-like protein Det1 PF09737.4 GAM21490.1 - 2.1e-110 369.3 10.3 9.5e-80 268.3 2.3 2.4 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 Pkinase PF00069.20 GAM21491.1 - 3.5e-61 206.6 0.0 4.7e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21491.1 - 7e-44 149.8 0.0 1.1e-43 149.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM21491.1 - 0.0043 16.8 0.1 0.048 13.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM21491.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dicty_REP PF05086.7 GAM21491.1 - 0.6 7.8 8.5 0.85 7.2 5.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M6 PF05547.6 GAM21493.1 - 0.12 10.3 0.0 0.13 10.3 0.0 1.0 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 SAP PF02037.22 GAM21494.1 - 3.9e-07 29.4 0.0 1.4e-05 24.4 0.0 2.8 2 0 0 2 2 2 1 SAP domain BUD22 PF09073.5 GAM21494.1 - 0.00061 18.9 6.4 0.00087 18.4 4.4 1.3 1 0 0 1 1 1 1 BUD22 Daxx PF03344.10 GAM21494.1 - 0.0057 15.2 9.9 0.0084 14.6 6.9 1.2 1 0 0 1 1 1 1 Daxx Family CENP-B_dimeris PF09026.5 GAM21494.1 - 0.044 14.0 22.3 0.65 10.2 1.7 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 GAM21494.1 - 0.36 10.3 16.9 0.39 10.2 3.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin Nop25 PF09805.4 GAM21494.1 - 0.93 9.5 10.4 2.6 8.1 7.2 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.7 GAM21494.1 - 1.1 8.4 12.4 1.8 7.7 8.6 1.3 1 0 0 1 1 1 0 SDA1 F-protein PF00469.15 GAM21494.1 - 1.2 8.4 5.0 2.3 7.5 3.5 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Atrophin-1 PF03154.10 GAM21494.1 - 1.3 7.0 12.1 1.7 6.7 8.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Nop14 PF04147.7 GAM21494.1 - 1.4 6.7 14.7 2.2 6.1 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAM21494.1 - 1.5 6.7 9.8 2.1 6.2 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 GAM21494.1 - 1.7 6.9 15.5 2.7 6.2 10.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lactamase_B_2 PF12706.2 GAM21495.1 - 1.1e-22 80.5 4.3 8.7e-22 77.6 0.5 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM21495.1 - 2.9e-06 27.0 1.7 5.5e-06 26.1 0.0 2.2 3 1 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 GAM21495.1 - 0.0026 17.1 0.0 0.04 13.3 0.0 2.9 3 0 0 3 3 3 1 tRNase Z endonuclease Pyridox_oxidase PF01243.15 GAM21495.1 - 0.11 12.5 0.2 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase HAD PF12710.2 GAM21496.1 - 2.8e-16 60.2 0.0 1.1e-15 58.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM21496.1 - 3.8e-16 58.8 0.0 3.8e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM21496.1 - 3.8e-16 60.1 0.1 2.4e-14 54.2 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM21496.1 - 1.1e-13 50.8 0.0 9.3e-13 47.9 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM21496.1 - 0.00051 19.6 0.1 0.0098 15.4 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Borrelia_P83 PF05262.6 GAM21497.1 - 1.5 7.0 10.3 2.4 6.3 7.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.14 GAM21497.1 - 6.3 4.5 9.8 10 3.8 6.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adeno_E3_CR2 PF02439.10 GAM21498.1 - 0.00056 19.3 2.4 0.00087 18.7 1.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Shisa PF13908.1 GAM21498.1 - 0.0035 17.5 0.1 0.0041 17.3 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3169 PF11368.3 GAM21498.1 - 0.0046 16.2 0.7 0.0061 15.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) SP_C-Propep PF08999.5 GAM21498.1 - 0.0063 15.9 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide DUF1310 PF07006.6 GAM21498.1 - 0.03 13.8 0.9 0.039 13.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) DUF690 PF05108.8 GAM21498.1 - 0.033 12.5 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) MethyltransfD12 PF02086.10 GAM21498.1 - 0.034 13.6 1.5 0.044 13.2 1.0 1.1 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Tetraspannin PF00335.15 GAM21498.1 - 0.036 13.3 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Reovirus_cap PF00979.12 GAM21498.1 - 0.062 12.2 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 P12 PF12669.2 GAM21498.1 - 0.072 13.3 2.2 0.11 12.7 1.5 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family tRNA_anti-like PF12869.2 GAM21498.1 - 0.073 12.5 1.1 0.089 12.2 0.8 1.3 1 1 0 1 1 1 0 tRNA_anti-like Amnionless PF14828.1 GAM21498.1 - 0.092 11.2 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.1 GAM21498.1 - 0.2 12.0 2.2 0.34 11.3 1.5 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3139 PF11337.3 GAM21498.1 - 1.3 9.3 7.0 9.1 6.6 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) COX6C PF02937.10 GAM21498.1 - 2.7 7.9 5.1 1.2e+02 2.7 3.5 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIc Arf PF00025.16 GAM21499.1 - 1.2e-53 180.9 0.0 1.4e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM21499.1 - 1.8e-15 56.6 0.0 2.1e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM21499.1 - 2.7e-13 49.6 0.0 3.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM21499.1 - 9.1e-12 44.3 0.6 6.3e-10 38.2 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 GAM21499.1 - 1.1e-09 38.8 0.0 1.5e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM21499.1 - 1e-08 34.5 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM21499.1 - 4.9e-07 29.7 0.0 6.4e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM21499.1 - 0.0026 17.2 0.1 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 GAM21499.1 - 0.015 15.6 0.1 0.022 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 GAM21499.1 - 0.017 14.3 0.1 0.055 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 GAM21499.1 - 0.017 14.5 0.6 0.038 13.4 0.3 1.7 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 GAM21499.1 - 0.028 14.3 0.8 0.18 11.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAM21499.1 - 0.031 13.3 0.0 0.037 13.1 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 GAM21499.1 - 0.043 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM21499.1 - 0.046 13.3 0.1 0.18 11.4 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 GAM21499.1 - 0.048 13.5 0.1 0.25 11.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 GAM21499.1 - 0.048 13.1 0.1 0.42 10.1 0.1 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.14 GAM21499.1 - 0.054 12.9 0.2 3.2 7.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 6PF2K PF01591.13 GAM21499.1 - 0.11 11.5 0.1 0.21 10.6 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Pik1 PF11522.3 GAM21499.1 - 0.18 11.6 0.5 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Nop25 PF09805.4 GAM21500.1 - 0.011 15.7 3.9 0.011 15.7 2.7 2.8 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) DUF1192 PF06698.6 GAM21500.1 - 0.027 14.2 0.7 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FlxA PF14282.1 GAM21500.1 - 7.2 6.6 11.3 45 4.0 0.0 3.1 2 1 0 2 2 2 0 FlxA-like protein Syja_N PF02383.13 GAM21501.1 - 9.4e-76 254.6 0.2 9.4e-76 254.6 0.2 3.3 4 0 0 4 4 4 1 SacI homology domain Exo_endo_phos PF03372.18 GAM21501.1 - 3.5e-24 86.1 0.3 1e-23 84.5 0.2 1.9 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 GAM21502.1 - 7.1e-28 96.0 3.4 1.2e-14 53.7 0.3 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21502.1 - 9.3e-23 80.0 0.6 2.3e-12 46.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21502.1 - 1.2e-09 37.8 0.7 2.5e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 GAM21502.1 - 0.015 15.2 1.0 4.9 7.2 0.1 3.0 2 1 0 2 2 2 0 Nmi/IFP 35 domain (NID) HHH_2 PF12826.2 GAM21504.1 - 9.8e-05 22.1 0.0 0.00014 21.6 0.0 1.3 1 1 0 1 1 1 1 Helix-hairpin-helix motif Sec63 PF02889.11 GAM21504.1 - 0.007 15.6 0.2 0.0081 15.4 0.1 1.1 1 0 0 1 1 1 1 Sec63 Brl domain VCBS PF13517.1 GAM21505.1 - 3.7e-25 88.0 14.7 5.5e-08 33.0 1.6 5.6 5 2 1 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAM21505.1 - 6.5e-08 32.0 19.4 0.023 14.3 1.3 6.4 6 0 0 6 6 6 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 GAM21505.1 - 0.00053 19.4 3.3 0.17 11.2 0.0 3.8 4 2 1 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region TIG PF01833.19 GAM21506.1 - 5.5e-06 26.2 25.3 0.0047 16.8 0.4 5.3 5 0 0 5 5 5 4 IPT/TIG domain DUF4469 PF14734.1 GAM21507.1 - 0.017 15.0 0.1 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold TIG PF01833.19 GAM21507.1 - 0.055 13.4 1.0 0.078 12.9 0.4 1.6 1 1 0 1 1 1 0 IPT/TIG domain TIG PF01833.19 GAM21508.1 - 1.4 9.0 12.1 0.82 9.7 0.3 2.5 2 0 0 2 2 2 0 IPT/TIG domain Pkinase PF00069.20 GAM21509.1 - 1.6e-62 211.0 0.3 1e-61 208.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21509.1 - 1.7e-47 161.7 0.0 4.3e-47 160.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM21509.1 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM21509.1 - 0.13 11.9 1.2 0.61 9.7 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family TLD PF07534.11 GAM21510.1 - 3.6e-40 137.1 0.4 1.2e-39 135.5 0.3 1.8 1 0 0 1 1 1 1 TLD Dimer_Tnp_hAT PF05699.9 GAM21511.1 - 6.1e-11 41.8 0.1 1.2e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Exc PF07825.6 GAM21511.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Excisionase-like protein LPP PF04728.8 GAM21512.1 - 0.0038 16.9 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF883 PF05957.8 GAM21512.1 - 0.094 13.1 2.2 2.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 GAM21512.1 - 1 9.3 9.5 4.1 7.4 2.6 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Secretin_N_2 PF07655.8 GAM21513.1 - 0.0076 16.6 25.4 0.009 16.3 17.6 1.0 1 0 0 1 1 1 1 Secretin N-terminal domain NPR3 PF03666.8 GAM21513.1 - 0.034 12.6 3.6 0.035 12.6 2.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Kei1 PF08552.6 GAM21513.1 - 0.63 9.6 6.3 0.65 9.6 4.4 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.8 GAM21513.1 - 1.8 8.6 14.6 2.1 8.3 10.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bul1_C PF04426.7 GAM21513.1 - 2 7.5 7.9 2.2 7.4 5.4 1.0 1 0 0 1 1 1 0 Bul1 C terminus DUF572 PF04502.8 GAM21513.1 - 2.1 7.5 8.9 2.3 7.3 6.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAP25 PF15476.1 GAM21513.1 - 2.2 7.7 17.9 2.6 7.5 12.4 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Plasmodium_Vir PF05795.6 GAM21513.1 - 2.6 7.1 6.1 2.7 7.1 4.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDK2AP PF09806.4 GAM21513.1 - 6.5 6.9 16.1 8.3 6.5 11.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4614 PF15391.1 GAM21513.1 - 8.8 6.0 22.8 10 5.8 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apc15p PF05841.6 GAM21513.1 - 9 7.0 10.0 10 6.8 6.9 1.1 1 0 0 1 1 1 0 Apc15p protein AAA_21 PF13304.1 GAM21514.1 - 0.31 10.9 3.4 0.48 10.3 2.3 1.3 1 0 0 1 1 1 0 AAA domain Crystall_2 PF09076.5 GAM21515.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Toxin_R_bind_N PF07953.7 GAM21517.1 - 0.032 13.7 0.4 0.77 9.2 0.3 2.0 2 0 0 2 2 2 0 Clostridium neurotoxin, N-terminal receptor binding SpoIIE PF07228.7 GAM21518.1 - 1.8e-09 37.5 0.0 2.6e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 GAM21518.1 - 2.1e-05 24.0 0.1 0.11 11.8 0.0 2.7 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAM21518.1 - 3.1e-05 23.4 0.0 0.00041 19.8 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C OmdA PF13376.1 GAM21518.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Pkinase PF00069.20 GAM21519.1 - 1.1e-49 168.8 0.0 1.5e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21519.1 - 2.9e-19 69.1 0.0 9.9e-18 64.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM21519.1 - 0.0014 17.6 0.0 0.0073 15.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 GAM21519.1 - 0.0078 15.0 0.5 0.011 14.5 0.3 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 GAM21519.1 - 0.06 12.4 0.1 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB_2 PF02214.17 GAM21519.1 - 0.08 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain APH PF01636.18 GAM21519.1 - 0.14 11.8 0.1 0.43 10.2 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family dCMP_cyt_deam_1 PF00383.17 GAM21520.1 - 1.1e-14 53.9 1.2 2e-14 53.0 0.8 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PA14 PF07691.7 GAM21521.1 - 7e-11 41.9 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM21521.1 - 7.6e-05 22.4 4.8 7.6e-05 22.4 3.3 12.3 11 2 0 11 11 11 4 Dictyostelium (slime mold) repeat DiS_P_DiS PF06750.8 GAM21522.1 - 0.095 12.5 1.2 0.9 9.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain YyzF PF14116.1 GAM21522.1 - 0.67 9.9 3.8 9.5 6.2 0.1 3.0 3 0 0 3 3 3 0 YyzF-like protein zf-FCS PF06467.9 GAM21522.1 - 3.8 7.2 9.5 0.73 9.5 0.8 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Sgf11 PF08209.6 GAM21522.1 - 9.7 5.6 7.1 16 4.9 0.1 2.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Peptidase_M8 PF01457.11 GAM21523.1 - 1.4e-48 165.5 5.0 2.1e-48 164.9 3.4 1.2 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M91 PF14891.1 GAM21523.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Effector protein CPSase_L_D2 PF02786.12 GAM21524.1 - 1.4e-115 383.9 0.2 8.4e-84 280.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 GAM21524.1 - 5.6e-48 161.7 0.0 1.9e-47 160.0 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 GAM21524.1 - 2.9e-43 146.9 0.0 1e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 GAM21524.1 - 8.2e-42 142.8 0.0 2.7e-41 141.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 GAM21524.1 - 1.4e-40 137.8 0.1 3.2e-40 136.7 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 GAM21524.1 - 1.4e-36 125.9 0.2 1.1e-23 83.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RVT_1 PF00078.22 GAM21524.1 - 4.3e-36 124.3 0.0 1.1e-35 122.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CPSase_L_chain PF00289.17 GAM21524.1 - 3.2e-33 114.0 0.0 2.5e-17 62.9 0.0 3.1 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 GAM21524.1 - 1.5e-32 112.6 0.1 3.8e-32 111.3 0.1 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.8 GAM21524.1 - 1.1e-19 70.6 0.7 1.8e-10 40.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAM21524.1 - 9.9e-17 60.8 0.0 9.3e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 GAM21524.1 - 3.2e-16 59.0 0.0 1.3e-15 57.0 0.0 2.2 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 GAM21524.1 - 2.6e-15 55.9 0.2 7.1e-10 38.1 0.0 3.6 4 0 0 4 4 4 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 GAM21524.1 - 5.4e-10 39.3 0.3 2e-05 24.4 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Amidohydro_1 PF01979.15 GAM21524.1 - 4.4e-07 29.8 0.3 1.3e-06 28.2 0.2 1.9 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM21524.1 - 1.9e-06 28.1 0.0 0.021 14.8 0.0 2.8 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 GAM21524.1 - 8.8e-06 25.4 0.0 2.6e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase RimK PF08443.6 GAM21524.1 - 1.5e-05 24.5 0.1 0.00073 19.0 0.1 2.7 3 0 0 3 3 2 1 RimK-like ATP-grasp domain DHOase PF12890.2 GAM21524.1 - 0.018 14.7 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 Dihydro-orotase-like Amidohydro_3 PF07969.6 GAM21524.1 - 0.066 12.4 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase family Peptidase_C26 PF07722.8 GAM21524.1 - 1.3 8.3 4.1 1.3 8.4 0.1 2.7 2 1 1 3 3 3 0 Peptidase C26 DHO_dh PF01180.16 GAM21525.1 - 1.9e-20 73.0 0.1 4.5e-18 65.2 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Dus PF01207.12 GAM21525.1 - 6.2e-05 21.9 0.6 0.00068 18.5 0.1 2.0 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 GAM21525.1 - 0.085 12.1 0.0 0.7 9.1 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein HOOK PF05622.7 GAM21526.1 - 5e-64 216.3 81.5 6.2e-64 216.0 56.5 1.0 1 0 0 1 1 1 1 HOOK protein CH PF00307.26 GAM21526.1 - 0.00013 21.9 0.1 0.00013 21.9 0.0 3.5 4 0 0 4 4 4 1 Calponin homology (CH) domain Myosin_tail_1 PF01576.14 GAM21526.1 - 0.00081 17.2 57.2 0.00081 17.2 39.6 2.8 1 1 1 2 2 2 1 Myosin tail AAA_13 PF13166.1 GAM21526.1 - 0.0028 16.1 25.0 0.0028 16.1 17.3 4.0 2 2 2 4 4 4 3 AAA domain T2SF PF00482.18 GAM21526.1 - 0.67 9.8 11.3 5.6 6.8 0.6 4.4 3 2 1 4 4 4 0 Type II secretion system (T2SS), protein F Tropomyosin_1 PF12718.2 GAM21526.1 - 0.87 9.4 106.6 0.61 9.9 13.2 5.5 2 2 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 GAM21526.1 - 1.5 7.9 38.4 0.9 8.6 3.1 3.7 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Nop14 PF04147.7 GAM21528.1 - 0.00069 17.6 7.3 0.00069 17.6 5.1 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.8 GAM21528.1 - 0.00069 19.6 6.1 0.00069 19.6 4.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit VID27 PF08553.5 GAM21528.1 - 0.041 12.1 3.8 0.039 12.1 2.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 GAM21528.1 - 0.21 10.2 20.0 0.28 9.8 13.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 GAM21528.1 - 0.22 10.7 12.3 0.27 10.4 8.5 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 GAM21528.1 - 0.63 8.0 9.9 0.76 7.7 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Mak16 PF04874.9 GAM21528.1 - 0.86 9.7 16.2 1.2 9.3 10.8 1.6 1 1 0 1 1 1 0 Mak16 protein C-terminal region Daxx PF03344.10 GAM21528.1 - 2.3 6.5 14.2 2.6 6.3 9.8 1.2 1 0 0 1 1 1 0 Daxx Family S-antigen PF05756.6 GAM21528.1 - 3.9 7.5 9.5 6 6.9 6.6 1.4 1 0 0 1 1 1 0 S-antigen protein Sporozoite_P67 PF05642.6 GAM21528.1 - 9 4.0 8.7 10 3.8 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FNIP PF05725.7 GAM21529.1 - 8.7e-36 121.6 27.4 2.4e-07 30.6 0.2 8.5 6 1 0 8 8 8 6 FNIP Repeat DUF1769 PF08588.5 GAM21529.1 - 0.00026 20.8 1.8 7.3 6.6 0.0 5.6 2 2 4 6 6 6 1 Protein of unknown function (DUF1769) Actin PF00022.14 GAM21530.1 - 7e-163 541.6 0.0 7.9e-163 541.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM21530.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) bZIP_2 PF07716.10 GAM21531.1 - 4.2e-07 29.6 2.4 4.2e-07 29.6 1.7 3.7 4 1 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.16 GAM21531.1 - 1.1e-06 28.4 2.9 1.1e-06 28.4 2.0 2.6 3 0 0 3 3 3 1 bZIP transcription factor ABC_membrane_2 PF06472.10 GAM21533.1 - 9.1e-99 330.1 3.4 1.3e-98 329.6 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 GAM21533.1 - 8e-19 68.2 0.0 1.6e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 GAM21533.1 - 0.00012 21.5 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 GAM21533.1 - 0.00044 19.5 0.1 0.031 13.4 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM21533.1 - 0.001 19.1 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 GAM21533.1 - 0.0014 19.0 0.1 0.0041 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM21533.1 - 0.0027 18.5 0.0 0.0074 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain SbmA_BacA PF05992.7 GAM21533.1 - 0.0061 15.7 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.18 GAM21533.1 - 0.0075 15.7 0.2 0.017 14.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_19 PF13245.1 GAM21533.1 - 0.014 15.1 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain DUF815 PF05673.8 GAM21533.1 - 0.022 13.6 0.0 0.22 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.10 GAM21533.1 - 0.032 12.9 0.0 0.062 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Arch_ATPase PF01637.13 GAM21533.1 - 0.065 12.9 0.0 4.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 GAM21533.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MutS_V PF00488.16 GAM21533.1 - 0.081 12.3 0.1 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 MutS domain V Metallophos PF00149.23 GAM21534.1 - 3.6e-13 49.3 1.4 6e-13 48.6 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_1 PF05184.10 GAM21534.1 - 0.06 13.1 0.1 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 1 Peptidase_A22B PF04258.8 GAM21535.1 - 6e-79 265.6 15.4 7.2e-79 265.3 10.7 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Amastin PF07344.6 GAM21536.1 - 0.048 13.2 2.7 0.075 12.6 1.8 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein YedD PF13987.1 GAM21537.1 - 0.032 13.7 0.6 2.6 7.6 0.0 2.6 1 1 1 2 2 2 0 YedD-like protein DUF4414 PF14377.1 GAM21537.1 - 3.4 7.6 6.6 0.88 9.5 2.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) RNase_PH PF01138.16 GAM21538.1 - 4e-21 75.7 0.6 1.6e-20 73.7 0.4 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAM21538.1 - 8.5e-09 35.2 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Sedlin_N PF04628.8 GAM21539.1 - 1.8e-38 131.3 0.6 2.1e-38 131.1 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 GAM21539.1 - 3.9e-08 33.1 0.7 4.5e-08 32.9 0.5 1.2 1 0 0 1 1 1 1 Sybindin-like family RRM_1 PF00076.17 GAM21540.1 - 9.9e-20 69.9 0.2 9.1e-10 38.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21540.1 - 5.9e-16 58.0 1.5 6.9e-07 29.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21540.1 - 1.7e-12 47.1 0.0 2.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM21540.1 - 0.029 14.1 0.3 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Baculo_PEP_C PF04513.7 GAM21541.1 - 1.4e-07 31.4 7.5 1.8e-05 24.6 1.2 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 GAM21541.1 - 5e-05 22.6 11.3 0.0009 18.5 2.9 1.8 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Laminin_II PF06009.7 GAM21541.1 - 0.00034 20.3 8.8 0.0017 18.1 1.9 3.0 1 1 2 3 3 3 1 Laminin Domain II AAA_13 PF13166.1 GAM21541.1 - 0.0042 15.6 14.0 0.0047 15.4 9.4 1.3 1 1 0 1 1 1 1 AAA domain DUF1664 PF07889.7 GAM21541.1 - 0.0043 16.8 2.5 0.0043 16.8 1.8 3.1 1 1 1 3 3 3 1 Protein of unknown function (DUF1664) SF-assemblin PF06705.6 GAM21541.1 - 0.0091 15.1 14.8 0.024 13.8 5.6 2.5 1 1 1 2 2 2 1 SF-assemblin/beta giardin Filament PF00038.16 GAM21541.1 - 0.014 14.9 8.2 0.0083 15.6 1.8 2.4 1 1 1 2 2 2 0 Intermediate filament protein Apolipoprotein PF01442.13 GAM21541.1 - 0.046 13.2 1.2 0.45 9.9 0.8 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3890 PF13029.1 GAM21541.1 - 0.056 13.4 2.0 0.16 11.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3890) IncA PF04156.9 GAM21541.1 - 0.078 12.5 5.4 0.049 13.2 1.7 2.1 2 1 0 2 2 2 0 IncA protein COG2 PF06148.6 GAM21541.1 - 0.096 12.5 10.7 0.28 11.0 0.5 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 STAT_alpha PF01017.15 GAM21541.1 - 0.18 11.4 5.3 0.58 9.8 2.7 2.2 1 1 0 1 1 1 0 STAT protein, all-alpha domain Uds1 PF15456.1 GAM21541.1 - 0.21 11.5 7.2 1.9 8.4 1.1 3.3 1 1 1 2 2 2 0 Up-regulated During Septation NPV_P10 PF05531.7 GAM21541.1 - 0.21 11.8 8.7 4.5 7.5 0.1 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 GAM21541.1 - 0.25 11.2 12.9 0.15 11.8 3.5 2.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSBP1 PF06825.7 GAM21541.1 - 0.27 10.8 7.9 1.4 8.5 0.8 3.4 2 1 1 3 3 3 0 Heat shock factor binding protein 1 FlgN PF05130.7 GAM21541.1 - 0.28 11.4 3.9 0.13 12.5 0.8 2.0 2 1 0 2 2 2 0 FlgN protein FlaC_arch PF05377.6 GAM21541.1 - 0.3 10.9 0.1 0.3 10.9 0.1 3.9 3 2 0 4 4 4 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.13 GAM21541.1 - 0.34 10.6 4.0 3.4 7.4 0.2 2.8 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Occludin_ELL PF07303.8 GAM21541.1 - 0.36 11.5 10.3 0.49 11.1 1.6 2.9 1 1 2 3 3 3 0 Occludin homology domain DUF2115 PF09888.4 GAM21541.1 - 0.42 10.7 6.0 0.12 12.5 1.5 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1515 PF07439.6 GAM21541.1 - 0.64 9.8 4.4 0.61 9.9 0.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) PMC2NT PF08066.7 GAM21541.1 - 0.84 9.9 10.8 6 7.2 0.3 3.2 2 1 1 3 3 3 0 PMC2NT (NUC016) domain FadA PF09403.5 GAM21541.1 - 1.4 8.9 10.4 0.39 10.7 0.7 3.0 1 1 1 3 3 3 0 Adhesion protein FadA Prominin PF05478.6 GAM21541.1 - 1.6 6.1 10.2 0.83 7.1 4.0 1.9 1 1 0 1 1 1 0 Prominin UPF0184 PF03670.8 GAM21541.1 - 2.4 8.3 10.9 6.1 7.0 0.1 3.7 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0184) FUN14 PF04930.10 GAM21541.1 - 2.4 8.4 5.5 7.1 6.9 0.1 2.8 2 1 1 3 3 3 0 FUN14 family Nup54 PF13874.1 GAM21541.1 - 2.7 7.6 9.4 0.78 9.4 0.7 2.8 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 TBCA PF02970.11 GAM21541.1 - 2.7 8.1 7.4 1.1 9.4 0.3 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A Seryl_tRNA_N PF02403.17 GAM21541.1 - 2.8 7.9 11.1 0.2 11.6 1.1 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MazG-like PF12643.2 GAM21541.1 - 3.1 7.7 6.6 7.7 6.5 0.1 3.0 3 0 0 3 3 3 0 MazG-like family DUF1640 PF07798.6 GAM21541.1 - 3.3 7.7 15.1 50 3.8 10.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TSC22 PF01166.13 GAM21541.1 - 3.4 7.6 7.5 5.7 6.9 0.0 3.7 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF4094 PF13334.1 GAM21541.1 - 4.3 7.7 6.8 0.76 10.2 0.9 2.4 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) Spc7 PF08317.6 GAM21541.1 - 4.9 5.7 17.1 0.64 8.6 6.5 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 GAM21541.1 - 8.1 6.5 15.0 12 5.9 5.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Lactamase_B PF00753.22 GAM21542.1 - 2.2e-25 89.4 4.1 2.8e-25 89.1 2.8 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM21542.1 - 3.8e-06 26.5 0.1 4.7e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM21542.1 - 0.00037 20.2 0.1 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Terpene_synth_C PF03936.11 GAM21543.1 - 0.012 14.8 0.1 0.018 14.2 0.0 1.5 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain Swi3 PF07962.7 GAM21545.1 - 6.1e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SR-25 PF10500.4 GAM21545.1 - 0.008 15.6 14.2 0.008 15.6 9.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3439 PF11921.3 GAM21545.1 - 0.0093 15.7 4.9 0.0093 15.7 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Nop14 PF04147.7 GAM21545.1 - 0.084 10.7 0.1 0.084 10.7 0.0 3.1 2 1 0 2 2 2 0 Nop14-like family Peptidase_M66 PF10462.4 GAM21546.1 - 1.4e-63 214.6 0.0 1.8e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.1 GAM21546.1 - 0.0014 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAM21546.1 - 0.0081 16.6 1.1 0.021 15.3 0.8 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 GAM21546.1 - 0.012 14.1 0.8 0.02 13.3 0.5 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M10 PF00413.19 GAM21546.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 GAM21546.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 GAM21546.1 - 0.15 11.9 0.2 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF3184 PF11380.3 GAM21547.1 - 1.9e-06 26.1 3.7 0.0058 14.6 0.3 3.0 1 1 1 3 3 3 3 Protein of unknown function (DUF3184) tRNA-synt_2d PF01409.15 GAM21549.1 - 9.6e-51 172.3 2.4 4.4e-31 107.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 GAM21549.1 - 7.2e-22 77.3 0.0 2.6e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain DUF2410 PF10307.4 GAM21550.1 - 1.6e-43 148.3 0.0 2.6e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) SSP160 PF06933.6 GAM21550.1 - 0.1 10.5 19.6 0.026 12.5 1.5 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 PUB PF09409.5 GAM21550.1 - 0.2 11.4 1.6 0.31 10.8 0.2 2.0 2 0 0 2 2 2 0 PUB domain FNIP PF05725.7 GAM21551.1 - 1.9e-46 155.7 19.1 2.4e-12 46.5 0.0 6.1 6 1 1 7 7 7 5 FNIP Repeat F-box-like PF12937.2 GAM21551.1 - 0.0094 15.6 0.3 0.029 14.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like Sulfotransfer_2 PF03567.9 GAM21552.1 - 2.2e-10 40.6 0.1 2.2e-10 40.6 0.1 2.2 2 1 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM21552.1 - 0.0003 19.5 1.2 0.0046 15.6 1.1 2.4 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase Cwf_Cwc_15 PF04889.7 GAM21552.1 - 0.95 9.1 16.3 2.1 8.0 11.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.5 GAM21552.1 - 1.4 8.8 13.2 2.5 8.0 9.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Glyco_hydro_20 PF00728.17 GAM21553.1 - 3.6e-70 236.8 0.9 4.7e-70 236.4 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM21553.1 - 6e-19 68.9 0.1 1.2e-18 68.0 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM21553.1 - 2.3e-05 24.9 0.0 3.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.17 GAM21554.1 - 3.7e-86 289.4 0.5 4.7e-86 289.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM21554.1 - 3.3e-20 73.0 0.1 5.5e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM21554.1 - 3.7e-06 27.5 0.0 5.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Endonuclease_5 PF04493.9 GAM21555.1 - 1.9e-52 177.6 0.0 2.4e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V SHOCT PF09851.4 GAM21555.1 - 0.012 15.0 0.2 0.025 14.0 0.1 1.5 1 1 0 1 1 1 0 Short C-terminal domain UvrC_HhH_N PF08459.6 GAM21555.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal MIP-T3 PF10243.4 GAM21555.1 - 0.29 9.5 5.9 0.41 9.0 4.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 GAM21555.1 - 2.4 6.3 8.1 3 6.0 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 GAM21555.1 - 2.6 6.3 10.5 3.6 5.8 7.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PHP_C PF13263.1 GAM21558.1 - 7.2 6.1 7.2 14 5.2 0.3 3.6 3 0 0 3 3 3 0 PHP-associated TIG PF01833.19 GAM21561.1 - 1.3e-299 967.2 467.1 2e-14 53.3 1.7 37.2 37 1 0 37 37 37 35 IPT/TIG domain Qn_am_d_aIII PF09099.5 GAM21561.1 - 7.2e-23 80.7 45.6 0.15 12.3 0.0 21.2 22 0 0 22 22 22 11 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DNase_II PF03265.10 GAM21561.1 - 6.4e-17 61.5 2.5 5e-16 58.6 0.6 2.7 2 1 0 2 2 2 1 Deoxyribonuclease II TIG PF01833.19 GAM21562.1 - 1.6e-80 265.1 79.2 3e-14 52.7 2.7 13.6 12 1 1 13 13 13 13 IPT/TIG domain DNase_II PF03265.10 GAM21562.1 - 2.5e-24 85.8 0.1 3.3e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 Deoxyribonuclease II Qn_am_d_aIII PF09099.5 GAM21562.1 - 0.0017 18.6 0.0 26 5.2 0.0 5.3 6 0 0 6 6 6 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Beta_helix PF13229.1 GAM21563.1 - 0.0027 17.4 21.9 0.0027 17.4 15.2 3.4 2 1 1 3 3 3 1 Right handed beta helix region RebB PF11747.3 GAM21563.1 - 1.4 8.8 13.8 0.026 14.4 4.2 2.2 2 0 0 2 2 2 0 Killing trait Pkinase PF00069.20 GAM21564.1 - 4.2e-75 252.2 0.0 6.1e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21564.1 - 4.3e-37 127.5 0.0 6.1e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 GAM21564.1 - 3e-11 42.5 0.0 5.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 GAM21564.1 - 1.3e-05 24.3 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM21564.1 - 0.00016 21.4 0.0 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM21564.1 - 0.0037 16.8 0.1 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 GAM21564.1 - 0.0052 15.8 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_20 PF00728.17 GAM21565.1 - 2.1e-69 234.3 0.1 1.6e-68 231.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain PP2C_2 PF13672.1 GAM21566.1 - 0.00019 20.9 0.1 0.00049 19.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C G-alpha PF00503.15 GAM21567.1 - 7e-117 390.3 3.6 8.5e-117 390.1 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM21567.1 - 1e-14 54.1 0.5 1.7e-11 43.7 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM21567.1 - 2.6e-06 26.7 3.3 0.00016 20.9 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM21567.1 - 0.0078 16.7 0.7 2 8.9 0.1 3.0 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 GAM21567.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 GAM21567.1 - 0.21 10.9 2.7 1.6 8.0 0.3 2.5 2 1 0 2 2 2 0 Ras family CLTH PF10607.4 GAM21568.1 - 6.8e-30 103.6 0.1 3.3e-29 101.4 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 GAM21568.1 - 3.3e-15 55.5 0.7 1.1e-14 53.7 0.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 GAM21568.1 - 0.0021 18.0 0.1 0.0048 16.8 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM21568.1 - 0.0025 17.5 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAM21568.1 - 0.004 16.9 0.5 0.0098 15.7 0.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAM21568.1 - 0.0083 15.8 0.2 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Rogdi_lz PF10259.4 GAM21568.1 - 0.012 14.7 0.4 0.018 14.1 0.3 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Rtf2 PF04641.7 GAM21568.1 - 0.013 14.7 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.20 GAM21568.1 - 0.028 14.0 0.5 0.028 14.0 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM21568.1 - 0.047 13.3 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0270 PF06794.7 GAM21568.1 - 0.11 12.3 0.2 0.39 10.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) LRR_4 PF12799.2 GAM21569.1 - 2.9e-26 90.5 46.9 1.9e-05 24.1 1.1 11.0 8 3 3 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM21569.1 - 1.3e-18 66.4 45.9 2e-06 27.4 0.5 8.1 7 2 1 8 8 8 6 Leucine rich repeat LRR_9 PF14580.1 GAM21569.1 - 4.3e-07 29.6 18.1 0.00014 21.5 0.1 5.8 5 2 2 7 7 7 3 Leucine-rich repeat LRR_7 PF13504.1 GAM21569.1 - 1.8e-05 24.2 43.9 1.9 9.0 0.4 14.3 16 0 0 16 16 16 3 Leucine rich repeat LRR_1 PF00560.28 GAM21569.1 - 4.4e-05 22.9 59.8 0.11 12.5 0.2 14.1 14 3 2 16 16 16 6 Leucine Rich Repeat ThiF PF00899.16 GAM21570.1 - 2.7e-36 124.3 0.0 4.6e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 GAM21570.1 - 8.2e-05 22.1 0.2 0.00052 19.5 0.1 2.4 3 0 0 3 3 3 1 MoeZ/MoeB domain ECSIT PF06239.6 GAM21570.1 - 0.0032 16.3 0.1 0.0061 15.4 0.1 1.4 1 0 0 1 1 1 1 Evolutionarily conserved signalling intermediate in Toll pathway 2-Hacid_dh_C PF02826.14 GAM21570.1 - 0.0097 15.0 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 GAM21570.1 - 0.028 13.8 0.0 0.072 12.4 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 GAM21570.1 - 0.18 10.4 0.1 7.5 5.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DAP PF15228.1 GAM21571.1 - 0.02 15.5 1.3 0.036 14.8 0.9 1.7 1 1 0 1 1 1 0 Death-associated protein ERCC4 PF02732.10 GAM21572.1 - 8.1e-05 22.4 0.0 0.00026 20.7 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain NTP_transferase PF00483.18 GAM21573.1 - 6.1e-47 159.9 0.0 8.3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 GAM21573.1 - 2.2e-09 37.6 0.0 2.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 GAM21573.1 - 2.2e-09 36.4 6.2 5.7e-07 28.7 1.1 3.9 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM21573.1 - 0.024 14.1 0.3 0.024 14.1 0.2 4.1 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase Cyclin_N PF00134.18 GAM21574.1 - 6e-33 113.1 0.3 6e-33 113.1 0.2 4.3 4 1 1 5 5 5 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM21574.1 - 6.5e-22 77.6 0.0 6.5e-22 77.6 0.0 4.3 4 0 0 4 4 4 1 Cyclin, C-terminal domain FNIP PF05725.7 GAM21575.1 - 5.1e-82 269.6 46.6 7e-13 48.3 0.4 12.5 10 2 4 14 14 14 12 FNIP Repeat DENN PF02141.16 GAM21576.1 - 7.6e-30 104.0 5.0 7e-28 97.6 0.0 3.3 3 0 0 3 3 3 2 DENN (AEX-3) domain dDENN PF03455.14 GAM21576.1 - 0.00056 19.9 0.4 0.0016 18.4 0.2 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.5 GAM21576.1 - 0.0021 17.7 0.1 0.0058 16.3 0.1 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis uDENN PF03456.13 GAM21576.1 - 0.004 17.0 4.1 0.05 13.5 2.9 2.8 1 1 0 1 1 1 1 uDENN domain Pkinase PF00069.20 GAM21577.1 - 7e-75 251.5 0.0 7e-75 251.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21577.1 - 6.7e-40 136.8 0.1 1.8e-39 135.3 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAM21577.1 - 0.0022 17.3 0.4 0.0038 16.5 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM21577.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YajC PF02699.10 GAM21577.1 - 4.5 7.0 7.5 8.8 6.0 0.8 2.5 2 0 0 2 2 2 0 Preprotein translocase subunit PAT1 PF09770.4 GAM21577.1 - 5.4 5.1 22.3 7.1 4.7 15.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF2_N PF00176.18 GAM21578.1 - 2.1e-51 174.5 2.7 4.2e-51 173.5 1.9 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM21578.1 - 3.1e-12 46.1 0.0 8.6e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_1 PF00536.25 GAM21578.1 - 3.9e-07 30.1 0.1 8.9e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM21578.1 - 1.4e-05 24.8 0.1 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Tyr-DNA_phospho PF06087.7 GAM21579.1 - 1.2e-65 221.8 0.9 2.6e-65 220.7 0.6 1.5 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 GAM21579.1 - 0.00013 21.6 0.1 0.0023 17.6 0.1 2.3 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 GAM21579.1 - 0.026 14.0 2.0 0.085 12.4 1.4 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF1479 PF07350.7 GAM21580.1 - 1.3e-12 46.9 0.3 4.3e-11 41.9 0.2 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 GAM21580.1 - 3.5e-05 23.9 0.1 0.0011 19.0 0.1 2.2 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Oxysterol_BP PF01237.13 GAM21581.1 - 1.1e-67 228.0 4.6 1.7e-67 227.4 3.2 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2829 PF11195.3 GAM21581.1 - 0.023 15.1 0.5 0.11 12.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) E1_dh PF00676.15 GAM21582.1 - 2.3e-108 361.4 0.2 2.7e-108 361.2 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAM21582.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.20 GAM21583.1 - 3.1e-46 157.6 0.0 5.9e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21583.1 - 2.7e-37 128.2 0.0 5.2e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGEF PF00621.15 GAM21583.1 - 3.1e-37 128.2 3.6 3.1e-37 128.2 2.5 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM21583.1 - 6.5e-06 26.2 0.0 3e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 PH domain Macoilin PF09726.4 GAM21583.1 - 0.0004 18.8 3.9 0.0004 18.8 2.7 1.9 3 0 0 3 3 3 1 Transmembrane protein TACC PF05010.9 GAM21583.1 - 0.0016 18.2 0.1 0.057 13.1 0.0 2.5 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) GAS PF13851.1 GAM21583.1 - 0.0057 15.8 4.3 0.0057 15.8 3.0 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding APH PF01636.18 GAM21583.1 - 0.039 13.6 0.0 0.33 10.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family IncA PF04156.9 GAM21583.1 - 0.26 10.8 6.0 0.056 13.0 0.6 2.2 3 0 0 3 3 3 0 IncA protein BLOC1_2 PF10046.4 GAM21583.1 - 5.6 7.1 11.7 1.8 8.7 1.0 3.7 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BCS1_N PF08740.6 GAM21585.1 - 2.8e-33 115.0 0.1 4.6e-33 114.4 0.0 1.3 1 1 0 1 1 1 1 BCS1 N terminal Urm1 PF09138.6 GAM21585.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Utp11 PF03998.8 GAM21586.1 - 4.2e-48 164.2 14.5 4.7e-48 164.1 10.0 1.0 1 0 0 1 1 1 1 Utp11 protein SH3_1 PF00018.23 GAM21587.1 - 2.3e-15 55.6 0.1 4.4e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM21587.1 - 3.5e-10 39.2 0.1 6.6e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM21587.1 - 9.9e-10 37.7 0.0 1.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Borrelia_orfX PF04160.7 GAM21588.1 - 0.062 13.1 2.0 0.073 12.8 1.4 1.0 1 0 0 1 1 1 0 Orf-X protein Peptidase_M1 PF01433.15 GAM21589.1 - 8.5e-138 459.6 0.1 1.9e-137 458.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 GAM21589.1 - 1.6e-54 185.3 0.3 2.5e-54 184.6 0.0 1.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAM21589.1 - 4.4e-20 72.0 0.2 8.8e-20 71.0 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Ribonuc_P_40 PF08584.6 GAM21590.1 - 3.3e-55 187.1 0.0 5.2e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit SSP160 PF06933.6 GAM21590.1 - 4 5.2 11.0 4 5.3 4.9 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Brix PF04427.13 GAM21592.1 - 2.2e-46 157.9 1.8 3.6e-46 157.2 0.2 1.8 2 0 0 2 2 2 1 Brix domain 7tm_3 PF00003.17 GAM21595.1 - 2e-33 115.7 19.3 3.9e-33 114.7 13.4 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 GAM21595.1 - 3.1e-17 62.3 0.0 4.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Basic membrane protein CLASP_N PF12348.3 GAM21596.1 - 9.3e-42 142.9 6.8 9.3e-42 142.9 4.7 1.8 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.2 GAM21596.1 - 0.00014 22.1 4.8 0.074 13.4 0.0 4.4 3 2 2 5 5 5 2 Vacuolar 14 Fab1-binding region UME PF08064.8 GAM21596.1 - 0.03 14.2 3.7 0.41 10.6 0.4 2.8 1 1 1 2 2 2 0 UME (NUC010) domain NPR2 PF06218.6 GAM21598.1 - 2e-127 425.4 8.2 2.2e-104 349.5 6.1 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 GAM21598.1 - 6.3e-07 28.2 1.1 0.0048 15.5 0.0 3.1 2 1 1 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.7 GAM21598.1 - 0.00081 19.4 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2250 PF10007.4 GAM21598.1 - 0.095 12.6 0.1 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) SAP PF02037.22 GAM21600.1 - 3.7e-06 26.3 0.2 2.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 SAP domain Nop14 PF04147.7 GAM21600.1 - 0.023 12.6 10.1 0.032 12.1 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAM21600.1 - 0.093 10.7 5.9 0.13 10.2 4.1 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 GAM21600.1 - 0.23 9.5 3.9 0.34 8.9 2.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 GAM21600.1 - 1.3 8.7 16.6 2.8 7.5 11.3 1.8 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 GAM21600.1 - 4.1 6.8 10.9 12 5.3 7.5 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SUZ PF12752.2 GAM21600.1 - 8.3 7.0 8.0 1 9.9 1.5 2.5 2 1 0 2 2 2 0 SUZ domain CUE PF02845.11 GAM21601.1 - 0.0088 15.5 0.6 1.3 8.5 0.0 4.2 3 2 0 3 3 3 1 CUE domain Tfb2 PF03849.9 GAM21602.1 - 0.019 13.6 1.6 0.021 13.4 1.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb2 Ycf1 PF05758.7 GAM21602.1 - 0.025 12.3 6.1 0.029 12.1 4.2 1.0 1 0 0 1 1 1 0 Ycf1 RNA_pol_3_Rpc31 PF11705.3 GAM21602.1 - 0.032 14.1 6.3 0.036 14.0 4.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cob_adeno_trans PF01923.13 GAM21602.1 - 0.067 12.9 5.2 0.091 12.5 3.6 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Bud13 PF09736.4 GAM21602.1 - 0.12 12.6 5.0 0.13 12.5 3.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FAM177 PF14774.1 GAM21602.1 - 0.23 11.3 5.3 0.35 10.8 3.6 1.3 1 0 0 1 1 1 0 FAM177 family DUF3835 PF12927.2 GAM21602.1 - 0.28 12.1 4.8 0.45 11.5 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) FAM222A PF15258.1 GAM21602.1 - 0.29 10.2 8.5 0.36 9.9 5.9 1.0 1 0 0 1 1 1 0 Protein family of FAM222A DUF1510 PF07423.6 GAM21602.1 - 0.47 9.7 8.2 0.6 9.4 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMPIT PF07851.8 GAM21602.1 - 3 6.8 7.7 3.8 6.4 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.9 GAM21602.1 - 4.3 7.2 14.3 5.7 6.8 9.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec7_N PF12783.2 GAM21603.1 - 5.3e-30 104.0 1.1 5.3e-30 104.0 0.7 5.7 6 1 0 6 6 6 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAM21603.1 - 1.7e-10 40.2 7.1 2.9e-10 39.5 0.4 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Calreticulin PF00262.13 GAM21604.1 - 3.6e-118 394.4 1.2 4.3e-118 394.1 0.8 1.1 1 0 0 1 1 1 1 Calreticulin family LMBR1 PF04791.11 GAM21605.1 - 1.6e-48 165.4 18.3 3.8e-48 164.2 12.7 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein TMF_TATA_bd PF12325.3 GAM21605.1 - 0.00087 19.0 0.6 0.0016 18.1 0.4 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 GAM21605.1 - 0.0077 16.1 0.7 0.014 15.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) DUF106 PF01956.11 GAM21605.1 - 4.5 6.7 8.1 0.99 8.9 0.0 3.3 3 0 0 3 3 3 0 Integral membrane protein DUF106 LRR_4 PF12799.2 GAM21606.1 - 1.7e-64 212.6 81.4 6.5e-10 38.4 1.4 12.5 8 3 5 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM21606.1 - 2.7e-47 158.3 59.3 3.3e-10 39.5 0.7 9.3 5 2 6 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 GAM21606.1 - 2.1e-46 148.8 56.0 0.0037 17.0 0.2 19.8 20 0 0 20 20 20 15 Leucine Rich Repeat LRR_7 PF13504.1 GAM21606.1 - 2.9e-28 92.9 54.7 0.05 13.7 0.1 18.6 19 0 0 19 19 19 8 Leucine rich repeat LRR_6 PF13516.1 GAM21606.1 - 3.1e-10 39.0 61.2 0.78 10.0 0.1 16.5 17 0 0 17 17 17 6 Leucine Rich repeat LRR_9 PF14580.1 GAM21606.1 - 0.0089 15.6 19.9 0.32 10.5 0.6 4.2 1 1 1 4 4 4 3 Leucine-rich repeat CheY-binding PF09078.6 GAM21606.1 - 0.009 15.9 6.3 5.8 7.0 0.0 5.2 6 0 0 6 6 6 1 CheY binding LRR_5 PF13306.1 GAM21606.1 - 2.6 7.7 6.1 5.5 6.7 0.2 3.2 2 2 1 3 3 3 0 Leucine rich repeats (6 copies) GST_N PF02798.15 GAM21607.1 - 6.9e-15 54.9 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM21607.1 - 2.5e-07 30.5 0.1 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM21607.1 - 1.5e-05 25.4 0.0 2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM21607.1 - 2.1e-05 24.6 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM21607.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM21607.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HMGL-like PF00682.14 GAM21608.1 - 1.8e-58 198.0 0.0 2.2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Molydop_binding PF01568.16 GAM21608.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF2089 PF09862.4 GAM21608.1 - 0.14 11.9 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Myotub-related PF06602.9 GAM21611.1 - 4.4e-06 25.7 8.4 0.0038 16.0 5.8 3.3 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAM21611.1 - 1.5e-05 25.3 0.1 0.0074 16.5 0.0 3.2 2 1 0 2 2 2 1 Tyrosine phosphatase family Mito_fiss_reg PF05308.6 GAM21611.1 - 0.0031 16.9 2.9 0.0031 16.9 2.0 2.9 3 0 0 3 3 3 1 Mitochondrial fission regulator Oxysterol_BP PF01237.13 GAM21612.1 - 2.6e-57 193.9 0.0 3.5e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein zf-C3HC4_3 PF13920.1 GAM21613.1 - 2e-07 30.5 12.6 3.1e-07 29.9 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM21613.1 - 0.00093 19.1 15.0 0.0015 18.4 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4366 PF14283.1 GAM21613.1 - 0.0012 18.3 1.5 0.0018 17.7 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) zf-RING_4 PF14570.1 GAM21613.1 - 0.0078 15.7 9.5 0.016 14.7 6.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 GAM21613.1 - 0.013 15.1 14.6 0.024 14.3 10.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM21613.1 - 0.017 14.7 14.3 0.03 13.9 9.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sporozoite_P67 PF05642.6 GAM21613.1 - 0.018 12.9 1.0 0.022 12.6 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 GAM21613.1 - 0.032 12.0 2.8 0.04 11.6 1.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_2 PF13639.1 GAM21613.1 - 0.047 13.5 14.7 0.078 12.8 10.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 GAM21613.1 - 0.13 12.0 5.6 6.4 6.6 3.5 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Viral_DNA_bp PF00747.12 GAM21613.1 - 0.21 8.7 1.5 0.29 8.2 1.1 1.2 1 0 0 1 1 1 0 ssDNA binding protein Ank_2 PF12796.2 GAM21614.1 - 0.0032 17.7 0.0 0.052 13.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM21614.1 - 0.0059 16.7 0.0 0.15 12.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat FNIP PF05725.7 GAM21615.1 - 3.2e-55 183.8 25.8 1.8e-16 59.7 0.2 7.0 4 2 1 7 7 7 6 FNIP Repeat F-box-like PF12937.2 GAM21615.1 - 2.1 8.1 4.8 0.99 9.1 0.1 2.7 3 0 0 3 3 3 0 F-box-like Ded_cyto PF06920.8 GAM21616.1 - 2.5e-46 157.1 0.1 5.8e-46 156.0 0.1 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM21616.1 - 2.5e-18 66.3 0.2 4.9e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.12 GAM21616.1 - 0.00022 20.6 0.2 0.0028 17.1 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAM21616.1 - 0.032 13.8 0.1 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain SH3_1 PF00018.23 GAM21616.1 - 0.18 11.1 0.0 0.47 9.8 0.0 1.7 1 0 0 1 1 1 0 SH3 domain zf-C3HC4_2 PF13923.1 GAM21617.1 - 1e-12 47.8 10.6 1.5e-12 47.3 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM21617.1 - 4.4e-12 45.6 11.0 6.5e-12 45.0 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM21617.1 - 3.4e-11 42.6 9.8 5.2e-11 42.0 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM21617.1 - 1.9e-10 40.3 9.0 2.7e-10 39.7 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM21617.1 - 3.6e-10 39.3 6.0 5.5e-10 38.7 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM21617.1 - 3.4e-08 33.2 10.8 5.7e-08 32.4 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM21617.1 - 1e-06 28.3 8.6 2.7e-06 26.9 1.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 GAM21617.1 - 1.7e-05 24.8 5.9 3e-05 24.0 4.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 GAM21617.1 - 6.7e-05 22.3 3.7 0.00012 21.4 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 GAM21617.1 - 0.00011 21.8 2.6 0.00021 20.9 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 GAM21617.1 - 0.00016 21.4 4.3 0.00025 20.7 3.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.7 GAM21617.1 - 0.0011 18.2 0.5 0.0018 17.5 0.3 1.3 1 1 0 1 1 1 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 GAM21617.1 - 0.0011 18.6 1.8 0.0016 18.1 1.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) U-box PF04564.10 GAM21617.1 - 0.0044 16.9 0.1 0.015 15.2 0.0 1.9 2 0 0 2 2 1 1 U-box domain zf-P11 PF03854.9 GAM21617.1 - 0.069 12.6 5.4 0.12 11.8 3.7 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.1 GAM21617.1 - 0.11 12.0 7.9 0.32 10.6 5.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 GAM21617.1 - 0.13 11.7 7.7 0.31 10.6 5.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TerY-C PF15616.1 GAM21617.1 - 0.21 11.5 4.0 0.31 10.9 2.8 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain RINGv PF12906.2 GAM21617.1 - 0.36 10.8 7.1 1.1 9.3 4.9 1.8 1 1 0 1 1 1 0 RING-variant domain zf-UDP PF14569.1 GAM21617.1 - 0.37 10.5 2.7 0.97 9.2 1.9 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger Sporozoite_P67 PF05642.6 GAM21617.1 - 1.4 6.7 6.4 1.7 6.3 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RasGEF PF00617.14 GAM21618.1 - 2.5e-52 177.3 1.3 5.1e-52 176.3 0.9 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM21618.1 - 7.5e-16 58.1 3.3 1.3e-15 57.3 0.8 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif Phospholip_B PF04916.8 GAM21619.1 - 1e-135 453.0 13.3 1.2e-135 452.7 9.2 1.0 1 0 0 1 1 1 1 Phospholipase B TENA_THI-4 PF03070.11 GAM21620.1 - 1.1e-24 87.3 0.6 1.3e-24 87.1 0.4 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Haem_oxygenas_2 PF14518.1 GAM21620.1 - 2.1e-14 53.5 0.0 3.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme Leader_Erm PF08253.6 GAM21621.1 - 0.013 14.9 0.4 0.02 14.3 0.3 1.4 1 0 0 1 1 1 0 Erm Leader peptide Oxysterol_BP PF01237.13 GAM21622.1 - 2.2e-53 180.9 0.1 3.2e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein A2M_N PF01835.14 GAM21623.1 - 1.3e-07 31.8 0.1 8.9e-07 29.0 0.1 2.5 2 0 0 2 2 2 1 MG2 domain A2M PF00207.17 GAM21623.1 - 3.4e-07 29.7 0.1 2e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family MG1 PF11974.3 GAM21623.1 - 6.5e-05 23.4 0.0 0.00043 20.7 0.0 2.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin MG1 domain A2M_N_2 PF07703.9 GAM21623.1 - 0.00021 21.0 0.2 0.0036 17.1 0.0 3.2 4 0 0 4 4 4 1 Alpha-2-macroglobulin family N-terminal region DUF824 PF05688.6 GAM21623.1 - 2.6 7.7 7.7 1.1 8.8 0.2 3.6 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) DUF829 PF05705.9 GAM21624.1 - 3.1e-17 63.0 0.0 5.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) RMP PF14996.1 GAM21624.1 - 0.14 12.0 3.1 0.2 11.5 2.1 1.2 1 0 0 1 1 1 0 Retinal Maintenance DUF829 PF05705.9 GAM21625.1 - 1.8e-16 60.5 0.5 2.1e-16 60.3 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PP2C PF00481.16 GAM21626.1 - 1.2e-62 211.6 0.0 1.9e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 GAM21626.1 - 4.4e-43 144.8 51.8 3.6e-09 36.2 1.6 9.4 5 3 4 9 9 9 8 Leucine rich repeat LRR_4 PF12799.2 GAM21626.1 - 1e-42 143.1 63.5 6.1e-08 32.1 0.8 12.2 8 3 4 12 12 12 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM21626.1 - 1.3e-24 82.4 62.7 0.082 12.9 0.1 17.6 16 1 1 17 17 17 10 Leucine Rich Repeat LRR_7 PF13504.1 GAM21626.1 - 2.3e-14 50.9 50.3 2.2 8.8 0.1 16.9 18 0 0 18 18 18 4 Leucine rich repeat LRR_6 PF13516.1 GAM21626.1 - 6.7e-07 28.7 52.5 0.38 10.9 0.5 14.7 16 0 0 16 16 16 4 Leucine Rich repeat PP2C_2 PF13672.1 GAM21626.1 - 2.9e-06 26.8 0.0 5.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM21626.1 - 0.0019 17.9 0.1 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) EGF_2 PF07974.8 GAM21628.1 - 1.1e-06 28.6 35.5 0.0012 18.9 11.7 2.8 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 GAM21628.1 - 0.16 11.9 29.4 0.29 11.1 9.1 2.9 2 1 0 2 2 2 0 EGF-like domain hEGF PF12661.2 GAM21628.1 - 0.56 10.4 6.5 0.19 11.8 0.5 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Frizzled PF01534.12 GAM21629.1 - 4.9e-09 35.4 19.5 6.5e-09 35.0 13.5 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.19 GAM21629.1 - 6.2e-06 25.4 16.4 9.7e-06 24.8 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4064 PF13273.1 GAM21629.1 - 0.38 10.8 0.0 0.38 10.8 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) MFS_1 PF07690.11 GAM21630.1 - 3.2e-19 68.8 21.1 4.3e-19 68.4 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 GAM21631.1 - 4.4e-08 32.2 28.7 4.4e-08 32.2 19.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sec62 PF03839.11 GAM21631.1 - 0.037 13.4 1.7 0.11 11.9 1.2 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4428 PF14471.1 GAM21631.1 - 0.55 10.0 6.7 0.11 12.2 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Arrestin_C PF02752.17 GAM21632.1 - 0.00013 22.0 9.3 0.00013 22.0 6.4 5.2 3 3 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain TraG-D_C PF12696.2 GAM21632.1 - 0.002 17.9 3.5 0.002 17.9 2.4 5.8 3 1 0 4 4 4 1 TraM recognition site of TraD and TraG Arrestin_N PF00339.24 GAM21632.1 - 0.018 14.8 0.1 0.018 14.8 0.1 5.0 5 0 0 5 5 5 0 Arrestin (or S-antigen), N-terminal domain RR_TM4-6 PF06459.7 GAM21632.1 - 1.3 8.8 23.5 0.18 11.6 13.0 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 GAM21632.1 - 3.8 6.1 7.1 9.2 4.8 4.9 1.7 1 0 0 1 1 1 0 Serine incorporator (Serinc) CLU PF13236.1 GAM21633.1 - 3e-47 160.9 0.0 5.7e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM21633.1 - 1.1e-12 48.2 0.6 3e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 EnY2 PF10163.4 GAM21633.1 - 0.014 15.3 0.1 0.055 13.3 0.1 2.0 1 0 0 1 1 1 0 Transcription factor e(y)2 LRR_6 PF13516.1 GAM21633.1 - 0.027 14.5 11.9 8.9 6.7 0.0 7.3 9 0 0 9 9 9 0 Leucine Rich repeat Macoilin PF09726.4 GAM21633.1 - 6.1 5.0 17.4 10 4.2 12.1 1.3 1 0 0 1 1 1 0 Transmembrane protein TBPIP PF07106.8 GAM21634.1 - 1.6e-26 92.8 4.8 2.8e-26 92.0 3.3 1.4 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 GAM21634.1 - 5e-05 23.0 2.4 5e-05 23.0 1.7 1.6 1 1 0 1 1 1 1 Mnd1 family Phage_GP20 PF06810.6 GAM21634.1 - 0.0051 16.2 8.5 0.0056 16.1 4.0 2.4 1 1 1 2 2 2 1 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.4 GAM21634.1 - 0.0055 16.5 7.4 0.0055 16.5 5.1 1.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 GAM21634.1 - 0.0072 15.6 6.3 0.0072 15.6 4.4 1.7 1 1 0 2 2 2 1 Mechanosensitive ion channel porin domain TSC22 PF01166.13 GAM21634.1 - 0.01 15.7 2.9 0.013 15.4 1.0 1.9 2 0 0 2 2 1 0 TSC-22/dip/bun family DUF4582 PF15189.1 GAM21634.1 - 0.016 14.4 0.3 0.03 13.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) IncA PF04156.9 GAM21634.1 - 0.029 13.9 11.5 0.073 12.6 8.0 1.7 1 1 0 1 1 1 0 IncA protein Bul1_C PF04426.7 GAM21634.1 - 0.029 13.5 3.4 0.039 13.1 2.4 1.1 1 0 0 1 1 1 0 Bul1 C terminus BLOC1_2 PF10046.4 GAM21634.1 - 0.031 14.4 1.1 0.068 13.3 0.7 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkip-1 PF06878.6 GAM21634.1 - 0.038 13.8 2.2 0.067 13.0 1.5 1.5 1 0 0 1 1 1 0 Pkip-1 protein SlyX PF04102.7 GAM21634.1 - 0.058 13.7 3.3 0.19 12.1 1.9 2.1 1 1 1 2 2 2 0 SlyX Reo_sigmaC PF04582.7 GAM21634.1 - 0.14 11.2 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 GAM21634.1 - 0.17 9.6 4.1 0.2 9.4 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.7 GAM21634.1 - 0.18 12.1 8.6 0.32 11.3 6.0 1.5 1 0 0 1 1 1 0 Striatin family MutS_II PF05188.12 GAM21634.1 - 0.19 11.8 1.4 0.3 11.1 0.3 1.7 1 1 1 2 2 2 0 MutS domain II ADIP PF11559.3 GAM21634.1 - 0.19 11.6 12.4 0.085 12.7 2.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.11 GAM21634.1 - 0.2 10.1 1.4 0.23 9.9 1.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4618 PF15397.1 GAM21634.1 - 0.34 10.1 8.4 1.3 8.3 0.8 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) APG6 PF04111.7 GAM21634.1 - 0.45 9.5 9.8 0.12 11.3 4.3 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 GAM21634.1 - 0.52 10.6 7.6 2.2 8.6 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 GAM21634.1 - 0.59 8.5 9.2 0.066 11.6 0.8 2.0 1 1 1 2 2 2 0 AAA domain Spc24 PF08286.6 GAM21634.1 - 0.75 9.5 8.4 0.88 9.2 4.4 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FlxA PF14282.1 GAM21634.1 - 1 9.3 7.3 0.37 10.7 2.8 2.0 2 0 0 2 2 2 0 FlxA-like protein CENP-Q PF13094.1 GAM21634.1 - 1.1 9.3 16.4 0.57 10.1 3.7 2.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 GAM21634.1 - 1.2 8.9 13.3 4.2 7.1 9.2 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 GAM21634.1 - 1.3 9.0 13.1 0.68 9.9 1.5 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 GAM21634.1 - 1.3 8.1 12.5 2.7 7.1 8.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding K-box PF01486.12 GAM21634.1 - 1.5 8.6 7.9 0.81 9.5 3.7 1.9 1 1 1 2 2 2 0 K-box region DUF904 PF06005.7 GAM21634.1 - 1.7 8.9 12.9 7.3 6.9 3.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Bap31 PF05529.7 GAM21634.1 - 1.8 7.9 4.9 0.24 10.8 0.3 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Fib_alpha PF08702.5 GAM21634.1 - 2.1 8.4 5.2 2.9 8.0 3.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.1 GAM21634.1 - 2.3 7.0 6.9 3.7 6.4 4.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.7 GAM21634.1 - 3 7.6 5.5 0.5 10.1 1.0 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DivIVA PF05103.8 GAM21634.1 - 3.5 7.6 10.7 13 5.8 5.6 2.3 1 1 1 2 2 2 0 DivIVA protein Prefoldin_2 PF01920.15 GAM21634.1 - 3.5 7.4 13.5 0.35 10.6 3.0 2.6 1 1 1 2 2 2 0 Prefoldin subunit CCDC-167 PF15188.1 GAM21634.1 - 6.9 6.6 7.0 1.8 8.5 0.8 2.7 2 1 0 3 3 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 GAM21634.1 - 7.1 6.2 10.7 0.3 10.6 1.9 2.6 2 1 0 2 2 2 0 Septum formation initiator GTP_EFTU PF00009.22 GAM21635.1 - 1e-33 116.3 0.6 2e-33 115.4 0.2 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 GAM21635.1 - 2.9e-08 33.7 0.8 1.9e-07 31.0 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM21635.1 - 3.2e-07 30.3 0.3 1.1e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM21635.1 - 8.2e-06 25.1 0.2 0.00053 19.2 0.2 2.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 GAM21635.1 - 0.0035 16.9 0.0 0.013 15.1 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 GAM21635.1 - 0.0097 15.3 4.2 2.1 7.8 0.0 3.0 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 GAM21635.1 - 0.024 15.1 0.1 0.082 13.4 0.1 2.0 1 1 0 1 1 1 0 Miro-like protein SNAP PF14938.1 GAM21636.1 - 2.3e-18 66.3 11.2 3.2e-18 65.8 7.8 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF4656 PF15551.1 GAM21636.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) TPR_12 PF13424.1 GAM21636.1 - 0.15 12.0 8.2 0.13 12.1 1.3 2.8 2 1 0 3 3 3 0 Tetratricopeptide repeat PhoU PF01895.14 GAM21636.1 - 0.19 12.1 1.8 4.8 7.6 0.0 3.2 2 1 0 2 2 2 0 PhoU domain TPR_8 PF13181.1 GAM21636.1 - 3 7.8 5.6 9.1 6.3 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat GYF PF02213.11 GAM21637.1 - 6.5e-16 57.6 0.1 6.5e-16 57.6 0.1 3.0 2 0 0 2 2 2 1 GYF domain DUF221 PF02714.10 GAM21638.1 - 3.2e-08 32.7 22.1 9.4e-07 27.9 4.9 2.9 2 0 0 2 2 2 2 Domain of unknown function DUF221 TRAP_alpha PF03896.11 GAM21638.1 - 0.067 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MNSV_P7B PF06692.6 GAM21638.1 - 0.13 12.0 7.1 0.036 13.8 0.5 2.9 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein Glyco_hydro_25 PF01183.15 GAM21639.1 - 2.2e-12 47.1 0.0 2.5e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Semialdhyde_dhC PF02774.13 GAM21640.1 - 1.1e-33 116.6 0.0 1.9e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 GAM21640.1 - 2.9e-29 101.8 0.1 5.3e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM21640.1 - 0.00063 19.6 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 GAM21640.1 - 0.0012 18.2 0.1 0.0037 16.7 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 GAM21640.1 - 0.014 15.9 0.0 0.043 14.3 0.0 1.9 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.1 GAM21640.1 - 0.039 13.9 0.1 0.085 12.8 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Esterase PF00756.15 GAM21641.1 - 3.7e-46 157.5 0.0 4.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 GAM21641.1 - 0.00029 19.7 0.0 0.11 11.4 0.0 3.0 3 0 0 3 3 3 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 GAM21641.1 - 0.00036 20.3 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM21641.1 - 0.00036 19.8 0.0 0.00049 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 GAM21641.1 - 0.0066 16.3 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 GAM21641.1 - 0.022 13.5 0.3 2.9 6.6 0.0 3.0 3 1 1 4 4 4 0 Chlorophyllase Abhydrolase_2 PF02230.11 GAM21641.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 GAM21641.1 - 0.075 12.6 1.0 1 8.8 0.7 2.2 1 1 0 1 1 1 0 PGAP1-like protein TACI-CRD2 PF09305.5 GAM21641.1 - 2.3 8.0 6.4 0.79 9.5 1.9 2.2 2 0 0 2 2 2 0 TACI, cysteine-rich domain Coiled PF05710.7 GAM21642.1 - 0.00017 21.9 3.2 0.00022 21.6 2.2 1.2 1 0 0 1 1 1 1 Coiled coil Glyco_tranf_2_2 PF10111.4 GAM21643.1 - 7.8e-11 41.5 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM21643.1 - 5.6e-08 32.6 0.0 9.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM21643.1 - 0.00099 18.9 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 GAM21643.1 - 0.0015 17.9 0.1 0.0037 16.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase TPR_11 PF13414.1 GAM21643.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 TPR repeat Zip PF02535.17 GAM21644.1 - 0.08 11.9 0.0 0.08 11.9 0.0 2.1 1 1 0 2 2 2 0 ZIP Zinc transporter LIM_bind PF01803.11 GAM21644.1 - 0.13 11.3 2.5 0.98 8.4 0.3 2.1 2 0 0 2 2 2 0 LIM-domain binding protein DUF4231 PF14015.1 GAM21644.1 - 1.1 9.2 5.8 1.7 8.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF912 PF06024.7 GAM21644.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AATF-Che1 PF13339.1 GAM21645.1 - 3.3e-26 91.9 6.9 3.3e-26 91.9 4.8 4.0 2 2 1 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 GAM21645.1 - 6.2e-16 58.2 0.2 6.2e-16 58.2 0.1 3.6 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal DEAD PF00270.24 GAM21646.1 - 5.5e-40 136.6 0.5 1.1e-39 135.5 0.3 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM21646.1 - 1.5e-24 85.6 0.3 4.6e-23 80.8 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 GAM21646.1 - 0.00074 19.2 0.5 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain CMS1 PF14617.1 GAM21646.1 - 0.0022 17.1 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 GAM21646.1 - 0.0029 17.4 0.1 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 GAM21646.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Helicase Fanconi_A PF03511.9 GAM21646.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein zf-CCCH PF00642.19 GAM21647.1 - 6.2e-13 48.0 17.6 3.7e-07 29.6 1.1 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAM21647.1 - 0.073 13.0 14.3 0.17 11.9 1.6 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C3H1 PF10650.4 GAM21647.1 - 2.5 7.6 9.7 7.2 6.1 0.2 3.4 3 0 0 3 3 3 0 Putative zinc-finger domain E1-E2_ATPase PF00122.15 GAM21648.1 - 2.6e-30 105.1 0.1 5.8e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAM21648.1 - 5.3e-25 88.7 0.0 1.1e-24 87.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM21648.1 - 1.1e-20 75.0 0.0 5.1e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 GAM21648.1 - 6.1e-14 51.8 0.8 6.1e-14 51.8 0.5 2.3 3 0 0 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 GAM21648.1 - 0.00029 20.2 0.0 0.00078 18.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM21648.1 - 0.00084 18.9 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM21648.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit YorP PF09629.5 GAM21648.1 - 0.072 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 YorP protein 2_5_RNA_ligase2 PF13563.1 GAM21649.1 - 1.2e-28 99.7 0.0 1.4e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 GAM21649.1 - 0.00047 20.0 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 LigT like Phosphoesterase GATA PF00320.22 GAM21650.1 - 2e-15 55.7 3.5 4.6e-15 54.6 2.4 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF4355 PF14265.1 GAM21650.1 - 0.01 15.7 9.3 0.01 15.7 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Cytochrome_C7 PF14522.1 GAM21650.1 - 0.18 11.4 4.0 0.59 9.8 2.8 1.9 1 0 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 GAM21650.1 - 7.1 7.0 14.3 0.42 10.9 5.6 2.2 2 0 0 2 2 2 0 Cytochrome c3 UQ_con PF00179.21 GAM21651.1 - 3.8e-49 165.7 0.0 4.3e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM21651.1 - 1.4e-06 28.1 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM21651.1 - 0.0032 17.3 0.2 0.0039 17.0 0.2 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 GAM21651.1 - 0.0073 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain Y_Y_Y PF07495.8 GAM21654.1 - 0.081 12.6 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain DUF3244 PF11589.3 GAM21654.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) DUF443 PF04276.7 GAM21655.1 - 0.0014 18.1 1.2 0.0016 17.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF443) BaxI_1 PF12811.2 GAM21655.1 - 0.003 16.7 0.1 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like DUF3464 PF11947.3 GAM21655.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) YlaC PF10777.4 GAM21655.1 - 0.21 11.1 3.2 0.9 9.0 0.1 2.2 2 0 0 2 2 2 0 Inner membrane protein YlaC DUF3278 PF11683.3 GAM21655.1 - 1.7 8.6 5.4 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) HXXEE PF13787.1 GAM21655.1 - 2.8 8.3 12.5 0.5 10.7 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Mito_carr PF00153.22 GAM21656.1 - 6.5e-69 227.7 4.7 4.8e-22 77.4 0.1 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein Tim17 PF02466.14 GAM21656.1 - 0.035 14.1 0.7 0.19 11.7 0.6 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family COG6 PF06419.6 GAM21657.1 - 6.8e-94 315.1 7.3 6.8e-86 288.7 1.4 2.0 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 Exo70 PF03081.10 GAM21657.1 - 0.00014 20.7 3.6 0.0016 17.3 0.0 2.7 3 0 0 3 3 3 2 Exo70 exocyst complex subunit DUF1240 PF06836.7 GAM21657.1 - 0.12 12.6 1.4 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Ank_2 PF12796.2 GAM21658.1 - 2.1e-09 37.5 0.2 6e-06 26.5 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM21658.1 - 1.3e-07 31.0 3.1 0.014 15.1 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 GAM21658.1 - 1.8e-06 28.2 2.1 0.52 10.8 0.1 5.3 3 3 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21658.1 - 2e-06 27.4 4.4 2.1 8.8 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 GAM21658.1 - 1.3e-05 25.2 0.3 2.2 8.6 0.0 4.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) UBA PF00627.26 GAM21658.1 - 0.053 13.3 0.0 11 6.0 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain MIP PF00230.15 GAM21659.1 - 1.5e-30 106.3 12.1 2.2e-30 105.8 8.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein PEPcase PF00311.12 GAM21660.1 - 1.5e-285 949.1 0.0 2.1e-285 948.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 GAM21660.1 - 8.3e-07 27.6 0.0 0.00035 19.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase Ldh_1_N PF00056.18 GAM21660.1 - 0.14 11.9 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Guanylate_cyc PF00211.15 GAM21661.1 - 9.9e-85 282.5 1.0 2.6e-44 150.8 0.7 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 GAM21661.1 - 3.9e-05 22.9 2.1 0.05 12.8 0.1 2.8 2 0 0 2 2 2 2 Heme NO binding associated RRM_1 PF00076.17 GAM21662.1 - 4.1e-54 180.0 3.3 9.5e-20 70.0 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM21662.1 - 1.4e-38 130.7 0.2 1.1e-11 44.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM21662.1 - 1.2e-29 101.8 2.9 2.4e-09 36.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM21662.1 - 0.0019 17.9 0.1 1.8 8.3 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 GAM21662.1 - 0.006 16.3 0.2 2.7 7.8 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.3 GAM21662.1 - 0.016 14.4 0.0 0.048 12.9 0.0 1.8 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF1517 PF07466.6 GAM21662.1 - 6.1 5.7 5.7 11 4.8 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) G8 PF10162.4 GAM21663.1 - 5.1e-25 87.6 0.1 1.3e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 G8 domain Vps26 PF03643.10 GAM21664.1 - 1.4e-47 161.7 0.2 1.8e-47 161.4 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 GAM21664.1 - 2.3e-12 46.9 0.1 6.3e-11 42.3 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LeuA_dimer PF08502.5 GAM21664.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Acyl_transf_3 PF01757.17 GAM21666.1 - 2.7e-24 85.6 32.2 2.7e-24 85.6 22.3 2.0 2 0 0 2 2 2 1 Acyltransferase family Imm-NTF2 PF15655.1 GAM21667.1 - 0.027 14.9 0.5 0.074 13.5 0.4 1.8 1 0 0 1 1 1 0 NTF2 fold immunity protein DUF2313 PF10076.4 GAM21667.1 - 0.069 12.5 0.1 0.3 10.4 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) Pox_H7 PF04787.7 GAM21667.1 - 0.07 12.9 2.5 0.87 9.3 0.3 2.4 1 1 1 2 2 2 0 Late protein H7 UBX PF00789.15 GAM21668.1 - 1.7e-14 53.6 0.4 7.4e-14 51.5 0.0 2.0 2 0 0 2 2 2 1 UBX domain SAPS PF04499.10 GAM21668.1 - 0.073 11.7 6.9 0.091 11.3 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2228 PF10228.4 GAM21668.1 - 0.08 12.4 5.1 0.17 11.4 3.5 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) HTH_36 PF13730.1 GAM21668.1 - 0.15 12.1 0.2 0.32 11.1 0.2 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain YMF19 PF02326.10 GAM21668.1 - 0.67 10.5 6.0 1.2 9.7 2.6 2.3 1 1 1 2 2 2 0 Plant ATP synthase F0 DUF543 PF04418.7 GAM21669.1 - 2.4e-08 33.8 0.0 4.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Herpes_pp38 PF04846.8 GAM21669.1 - 0.14 11.4 2.9 0.24 10.7 2.0 1.3 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Patatin PF01734.17 GAM21670.1 - 1.4e-23 83.8 0.2 3.3e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase ADH_zinc_N PF00107.21 GAM21671.1 - 3.2e-09 36.4 0.0 8e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM21671.1 - 0.00016 22.5 0.0 0.00043 21.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 GAM21671.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM21671.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 GAM21671.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.2 GAM21672.1 - 0.00047 20.5 0.0 0.00056 20.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Mg296 PF09644.5 GAM21672.1 - 0.12 12.1 1.6 0.22 11.3 1.1 1.5 1 1 0 1 1 1 0 Mg296 protein Exo_endo_phos PF03372.18 GAM21673.1 - 3.1e-31 109.1 0.0 4.9e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 GAM21673.1 - 6.8e-27 93.9 0.1 1.6e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain B3_4 PF03483.12 GAM21674.1 - 6.1e-24 84.4 0.1 1.1e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 GAM21674.1 - 1.3e-19 69.8 0.0 8.9e-17 60.6 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain MIF4G PF02854.14 GAM21674.1 - 0.04 13.3 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 MIF4G domain Chromate_transp PF02417.10 GAM21675.1 - 1.3e-17 63.9 25.0 1.4e-16 60.5 8.4 2.4 2 0 0 2 2 2 2 Chromate transporter DUF2946 PF11162.3 GAM21675.1 - 0.18 11.9 1.5 0.38 10.9 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF3325 PF11804.3 GAM21675.1 - 7.1 6.6 10.6 0.45 10.4 1.3 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) Xpo1 PF08389.7 GAM21676.1 - 1.2e-22 80.3 1.7 1.2e-22 80.3 1.2 3.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 GAM21676.1 - 1.4e-05 24.9 0.5 0.00018 21.3 0.3 2.9 1 1 0 1 1 1 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 GAM21676.1 - 0.008 16.1 0.1 0.22 11.5 0.0 3.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation IncA PF04156.9 GAM21679.1 - 0.01 15.4 0.5 0.024 14.2 0.3 1.6 1 0 0 1 1 1 0 IncA protein DUF745 PF05335.8 GAM21679.1 - 0.68 9.4 2.0 0.72 9.3 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) SIS PF01380.17 GAM21681.1 - 7.8e-19 67.5 0.2 1.3e-12 47.4 0.0 2.1 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.1 GAM21681.1 - 5.1e-05 22.9 0.2 0.21 11.2 0.0 3.2 2 1 1 3 3 3 2 SIS domain DUF1510 PF07423.6 GAM21682.1 - 0.0011 18.4 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Mem_trans PF03547.13 GAM21682.1 - 0.008 14.5 0.2 0.0085 14.4 0.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Pex24p PF06398.6 GAM21682.1 - 0.096 11.4 0.1 0.12 11.1 0.1 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin HSA PF07529.8 GAM21682.1 - 0.68 9.7 0.1 0.68 9.7 0.0 2.6 3 0 0 3 3 3 0 HSA DUF1325 PF07039.6 GAM21683.1 - 6.5e-32 109.8 0.7 1.3e-31 108.8 0.5 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Sporozoite_P67 PF05642.6 GAM21683.1 - 1.8e-05 22.8 11.6 2.5e-05 22.3 8.0 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF3498 PF12004.3 GAM21683.1 - 6.2e-05 22.3 9.2 7.7e-05 22.0 6.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) DUF966 PF06136.8 GAM21683.1 - 0.00074 19.0 11.1 0.001 18.5 7.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF966) DUF4537 PF15057.1 GAM21683.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) MitMem_reg PF13012.1 GAM21683.1 - 0.33 11.0 4.0 0.29 11.2 0.7 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Hid1 PF12722.2 GAM21683.1 - 1.2 6.7 12.3 1.5 6.4 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.1 GAM21683.1 - 3.7 5.7 10.5 5 5.3 6.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Mitofilin PF09731.4 GAM21683.1 - 6.5 5.2 16.2 8.4 4.9 11.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pneumo_att_G PF05539.6 GAM21683.1 - 8.1 5.7 28.0 11 5.2 19.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PRMT5 PF05185.11 GAM21684.1 - 7.2e-12 44.9 0.0 2.2e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 GAM21684.1 - 8.5e-09 35.7 0.0 8.4e-07 29.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.8 GAM21684.1 - 2.4e-08 33.4 0.1 5.6e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAM21684.1 - 1.7e-07 31.8 0.0 4.2e-07 30.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 GAM21684.1 - 5.4e-07 29.1 0.0 9.5e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM21684.1 - 5.9e-06 26.3 0.0 2.4e-05 24.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM21684.1 - 6e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAM21684.1 - 9.8e-05 21.6 0.1 0.00017 20.8 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 GAM21684.1 - 0.00028 21.2 0.0 0.00075 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM21684.1 - 0.00083 19.1 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAM21684.1 - 0.0018 17.9 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_9 PF08003.6 GAM21684.1 - 0.0028 16.4 0.1 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 GAM21684.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 GAM21684.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 GAM21684.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase 14-3-3 PF00244.15 GAM21685.1 - 3.3e-115 383.1 3.2 3.9e-115 382.8 2.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 GAM21685.1 - 0.12 11.9 3.4 0.54 9.7 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Man-6-P_recep PF02157.10 GAM21686.1 - 1.7e-07 30.5 2.0 5.4e-07 28.8 0.5 1.9 1 1 0 2 2 2 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.1 GAM21686.1 - 1.4e-05 24.5 0.1 2e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein CIMR PF00878.13 GAM21686.1 - 0.00029 20.6 1.3 0.21 11.3 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Ank_2 PF12796.2 GAM21687.1 - 1.7e-25 89.2 0.8 1e-08 35.3 0.0 5.4 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM21687.1 - 3e-15 55.8 7.2 1.6 9.1 0.0 9.9 5 3 5 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21687.1 - 2.6e-14 51.8 8.9 0.26 11.6 0.0 10.0 10 1 1 11 11 11 4 Ankyrin repeat Ank_4 PF13637.1 GAM21687.1 - 7.8e-12 45.3 7.2 0.042 14.3 0.0 8.9 8 2 2 10 10 10 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM21687.1 - 1.4e-11 43.5 3.7 0.87 9.5 0.0 8.0 7 0 0 7 7 7 3 Ankyrin repeat DUF3447 PF11929.3 GAM21687.1 - 2.6e-08 33.5 6.0 0.0026 17.5 0.1 5.9 3 2 2 5 5 5 3 Domain of unknown function (DUF3447) Annexin PF00191.15 GAM21688.1 - 1.9e-81 267.9 4.9 1.8e-23 82.1 0.0 4.1 4 0 0 4 4 4 4 Annexin Phage_portal_2 PF05136.8 GAM21688.1 - 0.078 11.4 0.1 0.12 10.8 0.0 1.4 2 0 0 2 2 2 0 Phage portal protein, lambda family Annexin PF00191.15 GAM21689.1 - 1.8e-74 245.5 2.8 1.3e-21 76.2 0.1 4.1 4 0 0 4 4 4 4 Annexin HEAT PF02985.17 GAM21690.1 - 3.9e-44 144.7 26.1 0.0036 17.2 0.1 22.0 24 0 0 24 24 24 13 HEAT repeat HEAT_2 PF13646.1 GAM21690.1 - 1.5e-42 143.7 21.2 1.8e-07 31.3 0.0 17.5 9 6 10 20 20 20 10 HEAT repeats HEAT_EZ PF13513.1 GAM21690.1 - 3.4e-33 113.2 30.1 0.019 15.4 0.0 19.2 17 3 3 20 20 20 10 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM21690.1 - 4.4e-21 75.0 0.0 3e-05 24.3 0.0 9.1 10 1 0 10 10 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM21690.1 - 2.2e-14 53.3 11.6 0.00034 20.0 0.0 8.2 8 0 0 8 8 8 3 CLASP N terminal DUF778 PF05608.7 GAM21690.1 - 0.18 11.7 3.7 22 5.0 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF778) Arm PF00514.18 GAM21690.1 - 2.1 8.2 13.1 52 3.8 0.0 7.5 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat tRNA-synt_2c PF01411.14 GAM21692.1 - 2.6e-181 603.6 0.0 3.6e-181 603.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAM21692.1 - 6e-15 54.8 0.0 1.7e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 GAM21692.1 - 2.3e-09 36.8 0.2 6.5e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 DHHA1 domain Ras PF00071.17 GAM21693.1 - 1.7e-48 164.1 0.0 2e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21693.1 - 3.1e-16 59.9 0.0 7.6e-16 58.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM21693.1 - 2.2e-12 46.5 0.0 2.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 GAM21693.1 - 0.0037 17.4 0.2 0.12 12.5 0.1 2.5 1 1 1 2 2 2 1 RNA helicase Gtr1_RagA PF04670.7 GAM21693.1 - 0.0081 15.3 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM21693.1 - 0.0081 14.8 0.2 0.61 8.7 0.0 2.8 2 1 1 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.1 GAM21693.1 - 0.054 13.0 0.2 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM21693.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 GAM21693.1 - 0.1 12.1 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 GAM21693.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 GAM21693.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Peptidase_M22 PF00814.20 GAM21694.1 - 3.3e-77 259.5 0.0 4e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family HEAT_EZ PF13513.1 GAM21695.1 - 5.2e-15 55.4 0.0 0.01 16.2 0.0 8.0 5 2 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.1 GAM21695.1 - 1.4e-13 50.8 0.1 0.0003 20.9 0.0 5.8 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 GAM21695.1 - 4.2e-08 32.6 6.6 0.0019 18.1 0.0 7.3 9 0 0 9 9 9 1 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM21695.1 - 4.5e-05 23.7 0.3 0.04 14.2 0.0 4.5 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region ParcG PF10274.4 GAM21695.1 - 0.00012 22.0 2.4 6 6.7 0.2 5.3 3 2 1 5 5 5 1 Parkin co-regulated protein MMS19_C PF12460.3 GAM21695.1 - 0.0021 16.8 20.2 0.099 11.3 0.1 5.2 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal DUF4042 PF13251.1 GAM21695.1 - 0.05 13.0 6.0 29 4.0 0.0 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) ABC_tran PF00005.22 GAM21696.1 - 5.7e-26 91.4 0.0 9.9e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAM21696.1 - 3.6e-18 65.7 27.7 6.1e-18 64.9 19.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM21696.1 - 1e-15 58.4 0.1 1e-10 42.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 GAM21696.1 - 0.00022 20.4 0.0 0.0013 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 GAM21696.1 - 0.014 14.6 0.0 0.47 9.6 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 GAM21696.1 - 0.093 12.6 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAM21696.1 - 0.26 11.6 0.2 0.49 10.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 GAM21697.1 - 1.9e-31 109.4 33.9 3.6e-31 108.4 23.5 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 GAM21697.1 - 5.6e-26 91.4 0.0 1.1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM21697.1 - 4.4e-09 36.7 1.7 3.9e-06 27.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 GAM21697.1 - 0.00013 21.1 0.4 0.071 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SRP54 PF00448.17 GAM21697.1 - 0.07 12.5 0.1 0.21 11.0 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2007 PF09413.5 GAM21697.1 - 0.077 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) DUF258 PF03193.11 GAM21697.1 - 0.091 11.9 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 GAM21697.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAM21697.1 - 0.11 12.0 0.3 0.24 10.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM21697.1 - 0.18 11.8 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 GAM21697.1 - 0.28 9.5 0.0 11 4.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 GAM21698.1 - 4.7e-48 161.9 0.8 3.4e-23 81.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 GAM21698.1 - 5.8e-23 80.6 2.6 6.2e-23 80.5 0.8 1.9 2 0 0 2 2 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 GAM21698.1 - 4.9e-22 77.8 0.1 6.2e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 GAM21698.1 - 6.1e-17 62.2 0.3 8e-07 29.5 0.1 3.3 2 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 GAM21698.1 - 2.7e-15 56.2 0.0 0.0012 18.3 0.0 5.4 4 2 0 4 4 4 4 Elongation factor Tu GTP binding domain AIG1 PF04548.11 GAM21698.1 - 2.2e-10 40.0 0.6 0.00042 19.4 0.1 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 GAM21698.1 - 3.1e-10 40.1 23.8 0.00051 19.8 0.0 6.2 5 1 0 5 5 4 4 Dynamin family DUF258 PF03193.11 GAM21698.1 - 1.6e-07 30.6 0.2 0.0035 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM21698.1 - 6.6e-06 26.2 0.6 0.0081 16.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain SRPRB PF09439.5 GAM21698.1 - 4.4e-05 22.7 0.4 0.032 13.4 0.0 2.8 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM21698.1 - 0.00011 21.5 0.5 0.18 11.1 0.1 2.9 2 1 0 2 2 2 2 Ras family cobW PF02492.14 GAM21698.1 - 0.00014 21.3 3.9 0.39 10.1 0.5 4.1 3 1 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 GAM21698.1 - 0.0002 21.0 0.0 0.083 12.5 0.0 3.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAM21698.1 - 0.00026 21.1 0.3 0.021 15.0 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 GAM21698.1 - 0.00041 19.6 1.6 1.9 7.6 0.1 3.8 2 2 0 2 2 2 2 ADP-ribosylation factor family AAA_10 PF12846.2 GAM21698.1 - 0.0023 17.4 1.0 0.88 8.9 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 GAM21698.1 - 0.003 17.4 0.4 5.4 6.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 GAM21698.1 - 0.0064 15.6 0.2 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 GAM21698.1 - 0.007 16.5 0.0 2 8.6 0.0 3.2 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 GAM21698.1 - 0.013 14.3 0.2 2 7.1 0.0 2.6 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 GAM21698.1 - 0.03 13.8 0.1 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM21698.1 - 0.039 13.3 0.1 14 4.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAM21698.1 - 0.045 13.7 0.1 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 GAM21698.1 - 0.11 12.4 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM21698.1 - 0.11 12.7 14.3 3.1 8.1 0.0 3.4 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 GAM21698.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.7 2 1 1 4 4 3 0 AAA domain AAA_17 PF13207.1 GAM21698.1 - 0.57 11.0 0.0 0.57 11.0 0.0 4.5 3 1 1 4 4 3 0 AAA domain DUF1032 PF06278.6 GAM21698.1 - 6.4 5.1 26.6 0.49 8.8 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1032) PARP PF00644.15 GAM21699.1 - 1.1e-32 113.2 0.1 9.2e-32 110.1 0.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAM21699.1 - 4.9e-18 65.0 0.4 2e-17 63.0 0.2 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_2 PF12796.2 GAM21699.1 - 1.1e-12 48.0 0.1 2.8e-09 37.1 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) WGR PF05406.10 GAM21699.1 - 1.3e-10 41.0 0.0 3.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 GAM21699.1 - 6.7e-10 38.9 0.7 1.8e-09 37.5 0.5 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ank_4 PF13637.1 GAM21699.1 - 9.2e-09 35.5 0.3 2.6e-06 27.7 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM21699.1 - 2e-08 33.6 0.0 6.9e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 GAM21699.1 - 3.5e-06 26.7 0.0 0.00012 21.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 GAM21699.1 - 4.5e-06 26.7 0.2 2.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PTCB-BRCT PF12738.2 GAM21699.1 - 0.00016 21.4 0.1 0.00059 19.6 0.1 2.0 1 0 0 1 1 1 1 twin BRCT domain Asp PF00026.18 GAM21700.1 - 1e-36 126.7 0.7 2.4e-23 82.8 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM21700.1 - 1.2e-15 57.4 0.0 2.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 GAM21700.1 - 3.2e-15 56.4 0.5 5.6e-15 55.6 0.3 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 GAM21700.1 - 0.063 13.7 0.0 1.8 9.1 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease PTH2 PF01981.11 GAM21701.1 - 2.5e-44 149.6 0.1 3.4e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 OSTbeta PF15048.1 GAM21701.1 - 0.014 15.4 0.1 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein FAM176 PF14851.1 GAM21701.1 - 0.049 13.3 0.2 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.1 GAM21701.1 - 0.087 12.9 2.0 0.088 12.9 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Tom22 PF04281.8 GAM21701.1 - 0.37 10.3 6.6 0.69 9.4 4.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Asparaginase_2 PF01112.13 GAM21702.1 - 2.4e-103 345.2 4.0 2.7e-103 345.0 2.7 1.0 1 0 0 1 1 1 1 Asparaginase Trypsin_2 PF13365.1 GAM21703.1 - 0.055 13.4 0.0 0.094 12.7 0.0 1.4 1 1 0 1 1 1 0 Trypsin-like peptidase domain 2-oxoacid_dh PF00198.18 GAM21704.1 - 1.1e-80 270.2 0.1 1.5e-80 269.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM21704.1 - 1.5e-20 72.5 0.4 3e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 GAM21704.1 - 0.00062 19.3 0.4 0.82 9.3 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Neisseria_TspB PF05616.8 GAM21704.1 - 0.41 8.9 5.2 0.7 8.1 3.6 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2360 PF10152.4 GAM21704.1 - 1.3 9.2 5.2 2.6 8.2 3.6 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DEAD PF00270.24 GAM21705.1 - 3.2e-43 147.1 0.0 8.5e-43 145.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM21705.1 - 5.8e-26 90.1 0.2 4.5e-25 87.3 0.3 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM21705.1 - 0.035 13.9 0.0 0.035 13.9 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit CTDII PF01556.13 GAM21706.1 - 9.7e-32 108.7 6.8 2.8e-20 72.0 0.3 3.4 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 GAM21706.1 - 5.7e-25 86.8 1.8 9.2e-25 86.1 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 GAM21706.1 - 1.3e-13 50.7 18.8 2.4e-13 49.8 13.0 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF866 PF05907.8 GAM21706.1 - 0.21 11.0 1.7 0.4 10.1 1.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Methyltransf_2 PF00891.13 GAM21708.1 - 2e-51 174.5 0.0 2.6e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM21708.1 - 1.6e-05 24.6 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM21708.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 GAM21709.1 - 6.4e-26 90.8 0.4 8.8e-26 90.3 0.2 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 GAM21709.1 - 6.5e-06 26.6 0.0 1.1e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM21709.1 - 8.4e-06 25.5 0.0 2e-05 24.3 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM21709.1 - 6.3e-05 23.3 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM21709.1 - 0.00039 19.8 0.1 0.00099 18.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM21709.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 GAM21709.1 - 0.009 15.0 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 GAM21709.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM21709.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 GAM21709.1 - 0.092 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 GAM21709.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.10 GAM21709.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Oxysterol_BP PF01237.13 GAM21710.1 - 0.022 13.2 0.6 0.064 11.7 0.4 1.7 1 1 0 1 1 1 0 Oxysterol-binding protein tRNA-synt_1 PF00133.17 GAM21711.1 - 4.8e-223 741.5 0.2 6.4e-223 741.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM21711.1 - 1.8e-25 89.4 0.7 3.7e-25 88.4 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM21711.1 - 6.1e-19 67.9 1.6 1.5e-06 27.1 0.3 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAM21711.1 - 3.4e-05 23.1 0.0 8.9e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 GAM21711.1 - 0.042 13.1 0.1 0.48 9.7 0.0 2.4 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 DUF2457 PF10446.4 GAM21712.1 - 0.015 14.0 8.6 0.016 13.9 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 GAM21712.1 - 2.7 7.1 11.9 4.7 6.3 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 GAM21712.1 - 4.2 7.7 11.5 1.2 9.5 5.7 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med13_C PF06333.7 GAM21714.1 - 5e-18 64.8 8.4 5e-18 64.8 5.8 6.5 5 2 1 6 6 6 2 Mediator complex subunit 13 C-terminal DUF3439 PF11921.3 GAM21714.1 - 1.2 8.8 13.7 0.083 12.6 5.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) DUF3496 PF12001.3 GAM21715.1 - 0.011 15.9 0.7 0.036 14.2 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) TMF_TATA_bd PF12325.3 GAM21715.1 - 0.017 14.8 0.6 0.017 14.8 0.4 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding STAT_int PF02865.12 GAM21715.1 - 0.053 13.4 2.0 0.75 9.7 0.5 2.2 2 0 0 2 2 2 0 STAT protein, protein interaction domain adh_short PF00106.20 GAM21716.1 - 8e-18 64.9 0.0 1.2e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM21716.1 - 1.9e-08 34.3 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM21716.1 - 3.6e-07 30.0 0.1 6.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM21716.1 - 0.00032 20.7 0.2 0.00057 19.9 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding ig PF00047.20 GAM21716.1 - 0.0023 17.9 0.0 0.008 16.2 0.0 1.8 1 1 0 1 1 1 1 Immunoglobulin domain Epimerase PF01370.16 GAM21716.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PMT_C PF11647.3 GAM21716.1 - 0.11 12.1 0.2 0.38 10.3 0.2 1.9 1 1 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 AbiH PF14253.1 GAM21717.1 - 0.084 12.4 0.3 0.085 12.4 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF3649 PF12365.3 GAM21719.1 - 0.03 13.8 0.1 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) DUF4611 PF15387.1 GAM21719.1 - 0.51 10.5 9.0 1.5 9.0 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 GAM21719.1 - 0.63 9.8 9.0 1.2 8.8 6.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.3 GAM21719.1 - 1.3 8.8 17.7 2.4 8.0 12.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.8 GAM21719.1 - 1.6 8.3 10.0 2.8 7.4 6.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 GAM21719.1 - 2.6 8.4 18.8 3.8 7.8 12.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 GAM21719.1 - 4.9 6.6 17.3 8.6 5.8 12.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin UPF0270 PF06794.7 GAM21720.1 - 0.015 15.0 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Pkinase PF00069.20 GAM21722.1 - 1.8e-34 119.0 0.0 4.3e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21722.1 - 4.4e-24 84.9 0.0 1.3e-23 83.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Dynamin_N PF00350.18 GAM21722.1 - 3.8e-14 52.8 0.1 1.7e-13 50.7 0.0 2.2 3 0 0 3 3 3 1 Dynamin family AAA_17 PF13207.1 GAM21722.1 - 0.0021 18.8 0.2 0.031 15.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM21722.1 - 0.0077 16.1 0.0 0.044 13.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAM21722.1 - 0.036 14.3 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 GAM21722.1 - 0.045 14.0 0.3 0.42 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Band_7 PF01145.20 GAM21722.1 - 0.047 13.6 0.2 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 SPFH domain / Band 7 family Dynamin_N PF00350.18 GAM21723.1 - 9e-09 35.3 0.0 3.3e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAM21723.1 - 0.00098 19.0 0.3 0.0048 16.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 GAM21723.1 - 0.0067 15.3 0.1 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 GAM21723.1 - 0.014 14.6 0.1 0.2 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF445 PF04286.7 GAM21723.1 - 0.015 14.8 0.8 0.025 14.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) AAA_29 PF13555.1 GAM21723.1 - 0.018 14.5 0.1 0.044 13.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM21723.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DOG1 PF14144.1 GAM21723.1 - 0.13 12.3 0.3 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 Seed dormancy control Pkinase PF00069.20 GAM21724.1 - 2.6e-31 108.7 0.0 1e-30 106.7 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21724.1 - 1.6e-20 73.2 0.0 4.7e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Dynamin_N PF00350.18 GAM21724.1 - 1.8e-10 40.8 0.0 6.2e-10 39.1 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAM21724.1 - 0.0012 18.7 0.0 0.0062 16.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.20 GAM21725.1 - 1.8e-18 66.6 2.6 1.8e-17 63.3 1.8 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21725.1 - 5e-13 48.7 0.8 2.3e-12 46.5 0.6 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM21726.1 - 4.3e-20 71.9 0.5 6e-19 68.2 0.3 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21726.1 - 4.7e-14 52.0 0.1 2.9e-13 49.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.18 GAM21726.1 - 2.3e-06 27.5 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_N PF00350.18 GAM21727.1 - 2.5e-12 46.9 0.0 6.4e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Pkinase_Tyr PF07714.12 GAM21727.1 - 1.8e-09 37.0 0.4 1.6e-06 27.4 0.3 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM21727.1 - 3.9e-07 29.4 2.0 7.9e-05 21.9 1.4 2.5 1 1 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.18 GAM21727.1 - 0.00021 21.1 0.0 0.0094 15.8 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.8 GAM21727.1 - 0.02 13.8 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 GAM21727.1 - 0.039 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 GAM21727.1 - 0.048 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 GAM21727.1 - 0.052 14.0 0.1 0.15 12.5 0.1 1.8 1 1 0 1 1 1 0 Miro-like protein TrwB_AAD_bind PF10412.4 GAM21727.1 - 0.055 12.0 0.0 0.099 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 GAM21727.1 - 0.07 13.9 0.6 0.63 10.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 GAM21727.1 - 0.082 13.0 0.0 0.72 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 GAM21727.1 - 0.12 12.6 0.9 0.4 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain SET PF00856.23 GAM21728.1 - 4.4e-07 30.3 0.2 7e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 SET domain zf-HIT PF04438.11 GAM21728.1 - 0.68 9.6 6.3 1.4 8.6 4.4 1.5 1 0 0 1 1 1 0 HIT zinc finger SET PF00856.23 GAM21729.1 - 5.6e-14 52.7 0.2 1.4e-12 48.2 0.1 2.4 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 GAM21729.1 - 2.2e-07 30.3 2.2 0.00057 19.4 0.4 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM21729.1 - 6.4e-06 25.6 0.6 0.02 14.7 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21729.1 - 0.0038 16.7 0.6 0.087 12.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21729.1 - 0.0047 17.0 0.0 0.017 15.3 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21729.1 - 0.028 14.1 0.2 0.65 9.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21729.1 - 0.37 10.7 3.4 4.3 7.3 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 GAM21730.1 - 2.2e-28 99.2 0.1 3.3e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM21730.1 - 1.9e-16 60.5 0.0 2.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM21730.1 - 2.5e-11 43.5 0.0 3.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM21730.1 - 3.5e-05 23.8 0.1 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM21730.1 - 9.4e-05 21.9 0.1 0.00024 20.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sigma70_ner PF04546.8 GAM21731.1 - 0.016 14.8 7.2 0.018 14.6 5.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 GAM21731.1 - 0.056 13.5 7.5 0.071 13.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 GAM21731.1 - 0.066 13.5 5.7 0.077 13.3 4.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 GAM21731.1 - 0.069 11.8 11.2 0.068 11.8 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3245 PF11595.3 GAM21731.1 - 0.11 12.7 5.3 0.12 12.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) SspB PF04386.8 GAM21731.1 - 0.13 11.8 2.4 0.14 11.7 1.7 1.1 1 0 0 1 1 1 0 Stringent starvation protein B CDC45 PF02724.9 GAM21731.1 - 0.13 10.2 6.6 0.12 10.3 4.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 GAM21731.1 - 0.31 11.3 6.6 0.35 11.1 4.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 GAM21731.1 - 0.32 10.6 3.9 0.34 10.5 2.7 1.1 1 0 0 1 1 1 0 FAM176 family Bd3614_N PF14442.1 GAM21731.1 - 0.4 10.6 5.8 0.47 10.4 4.0 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Sporozoite_P67 PF05642.6 GAM21731.1 - 0.43 8.3 8.8 0.43 8.3 6.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Vfa1 PF08432.5 GAM21731.1 - 0.57 10.1 8.8 0.59 10.1 6.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNase_H2_suC PF08615.6 GAM21731.1 - 0.58 9.9 3.7 0.68 9.7 2.6 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop25 PF09805.4 GAM21731.1 - 0.93 9.5 8.0 1.1 9.3 5.6 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.7 GAM21731.1 - 0.95 8.6 9.3 0.97 8.6 6.4 1.0 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 GAM21731.1 - 1.8 6.6 7.0 1.9 6.4 4.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Myc_N PF01056.13 GAM21731.1 - 3.1 6.8 6.4 3.2 6.8 4.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 GAM21731.1 - 8.7 5.2 9.2 9.3 5.1 6.4 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2648 PF10855.3 GAM21732.1 - 0.034 13.5 0.2 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Glyco_hydro_31 PF01055.21 GAM21733.1 - 2e-156 521.2 6.0 2.7e-156 520.8 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM21733.1 - 5.3e-22 77.4 0.9 1.4e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like GATA PF00320.22 GAM21734.1 - 7e-14 50.8 9.5 1.5e-13 49.8 4.2 2.6 2 0 0 2 2 2 1 GATA zinc finger zf-RING_3 PF14369.1 GAM21734.1 - 0.35 10.9 2.9 0.82 9.7 2.0 1.6 1 0 0 1 1 1 0 zinc-finger Uma2 PF05685.7 GAM21735.1 - 1.6e-07 30.8 0.0 4.2e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Putative restriction endonuclease Dynamin_N PF00350.18 GAM21736.1 - 3.7e-38 130.9 5.1 5.2e-38 130.4 0.0 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM21736.1 - 0.0001 22.2 0.0 0.00082 19.3 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM21736.1 - 0.029 14.8 0.0 0.11 13.0 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein HSP70 PF00012.15 GAM21736.1 - 0.057 11.3 4.3 0.12 10.2 3.0 1.4 1 0 0 1 1 1 0 Hsp70 protein DUF1664 PF07889.7 GAM21736.1 - 1.9 8.2 6.4 4.3 7.1 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FNIP PF05725.7 GAM21737.1 - 2.4e-26 91.3 20.2 1.7e-12 47.1 1.1 7.4 5 2 3 8 8 8 6 FNIP Repeat DUF1769 PF08588.5 GAM21737.1 - 0.0084 16.0 0.0 0.56 10.2 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM21738.1 - 2.7e-19 68.8 2.7 4.1e-08 33.0 0.0 5.7 6 0 0 6 6 6 5 FNIP Repeat Ank_2 PF12796.2 GAM21739.1 - 1.3e-07 31.8 16.2 0.051 13.9 1.2 7.9 5 3 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM21739.1 - 0.0012 18.9 8.7 43 4.7 0.0 8.3 7 1 2 9 9 9 0 Ankyrin repeat Ank_5 PF13857.1 GAM21739.1 - 0.0015 18.6 5.9 24 5.3 0.0 7.7 8 1 1 9 9 9 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM21739.1 - 0.038 14.5 7.6 1.1e+02 3.5 0.0 7.6 7 2 3 10 10 10 0 Ankyrin repeats (many copies) EF-hand_2 PF09068.6 GAM21739.1 - 0.065 13.3 3.1 0.36 10.8 0.1 3.5 3 0 0 3 3 3 0 EF hand FNIP PF05725.7 GAM21740.1 - 3.1e-16 59.0 16.6 6.7e-08 32.3 0.8 5.6 2 2 3 5 5 5 5 FNIP Repeat FNIP PF05725.7 GAM21741.1 - 7.6e-08 32.1 1.9 0.018 14.9 0.0 3.8 3 1 0 3 3 3 2 FNIP Repeat TPR_11 PF13414.1 GAM21742.1 - 8.8e-08 31.6 0.9 0.0094 15.5 0.0 3.4 2 1 1 3 3 3 2 TPR repeat SET PF00856.23 GAM21742.1 - 2.1e-07 31.3 8.6 7.5e-05 23.0 0.4 3.3 3 0 0 3 3 3 2 SET domain TPR_20 PF14561.1 GAM21742.1 - 4e-05 23.6 0.5 0.00016 21.7 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21742.1 - 0.00022 20.7 0.4 0.11 12.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21742.1 - 0.00039 20.6 0.0 0.0063 16.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21742.1 - 0.001 18.6 2.3 0.21 11.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21742.1 - 0.0016 18.4 0.1 0.009 16.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21742.1 - 0.019 14.8 1.0 0.7 9.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat CobT PF06213.7 GAM21742.1 - 6 5.9 28.0 14 4.6 19.4 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SET PF00856.23 GAM21743.1 - 3.8e-07 30.5 0.3 8.4e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 SET domain zf-C3HC4_3 PF13920.1 GAM21743.1 - 0.01 15.5 2.5 0.018 14.6 1.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spt4 PF06093.8 GAM21743.1 - 0.017 15.0 1.5 0.037 13.9 1.1 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger zinc-ribbons_6 PF07191.7 GAM21743.1 - 0.069 12.9 2.4 0.14 11.9 1.3 1.7 2 0 0 2 2 2 0 zinc-ribbons Apc3 PF12895.2 GAM21745.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SET PF00856.23 GAM21746.1 - 8.7e-08 32.6 0.0 1.7e-06 28.4 0.0 2.5 1 1 0 1 1 1 1 SET domain FYVE PF01363.16 GAM21746.1 - 0.023 14.5 3.2 0.051 13.4 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger Herpes_UL4 PF03277.8 GAM21746.1 - 0.046 12.9 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF3829 PF12889.2 GAM21746.1 - 0.076 12.1 0.4 0.14 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DSHCT PF08148.7 GAM21746.1 - 0.098 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 DSHCT (NUC185) domain zf-LITAF-like PF10601.4 GAM21746.1 - 0.44 10.4 7.8 1.6 8.6 0.0 3.5 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain AAA_22 PF13401.1 GAM21748.1 - 0.0026 17.9 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 GAM21748.1 - 0.012 14.6 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SET PF00856.23 GAM21750.1 - 2e-10 41.2 1.0 4.4e-09 36.8 0.7 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 GAM21750.1 - 0.00037 20.0 0.5 0.3 10.7 0.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 GAM21750.1 - 0.00038 20.3 0.0 0.017 15.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21750.1 - 0.0016 17.9 0.0 0.18 11.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat FYVE PF01363.16 GAM21750.1 - 0.0021 17.8 4.0 0.0021 17.8 2.8 2.4 2 0 0 2 2 2 1 FYVE zinc finger G6PD_N PF00479.17 GAM21750.1 - 0.034 14.3 0.8 0.39 10.9 0.0 2.9 3 0 0 3 3 3 0 Glucose-6-phosphate dehydrogenase, NAD binding domain TPR_7 PF13176.1 GAM21750.1 - 0.11 12.3 0.1 2.2 8.2 0.1 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.23 GAM21751.1 - 9.9e-12 45.4 0.0 4.1e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 GAM21751.1 - 0.0092 15.6 0.1 0.33 10.6 0.0 2.4 2 0 0 2 2 2 1 TPR repeat CheB_methylest PF01339.12 GAM21751.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase TPR_11 PF13414.1 GAM21752.1 - 8.3e-10 38.1 0.0 5e-05 22.8 0.0 2.7 1 1 1 2 2 2 2 TPR repeat SET PF00856.23 GAM21752.1 - 2e-07 31.4 0.1 3.2e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.23 GAM21752.1 - 3.1e-07 29.7 0.0 0.00012 21.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21752.1 - 5.6e-05 22.7 0.1 0.021 14.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21752.1 - 0.00024 21.0 1.7 0.0019 18.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21752.1 - 0.00054 19.5 0.2 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21752.1 - 0.00086 19.1 0.7 0.037 13.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM21752.1 - 0.022 14.8 0.1 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21752.1 - 0.046 13.5 0.0 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21752.1 - 0.095 13.0 0.0 0.56 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM21752.1 - 0.096 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.23 GAM21753.1 - 1.5e-09 38.3 0.9 4.5e-08 33.5 0.7 2.7 1 1 0 1 1 1 1 SET domain SAF PF08666.7 GAM21753.1 - 0.094 13.1 0.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 SAF domain TPR_2 PF07719.12 GAM21753.1 - 5.4 7.1 12.5 3.6 7.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat HypA PF01155.14 GAM21753.1 - 8.7 6.0 11.0 0.78 9.4 0.1 2.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family TPR_11 PF13414.1 GAM21754.1 - 4.5e-08 32.6 0.3 0.0019 17.7 0.0 2.9 1 1 1 2 2 2 2 TPR repeat SET PF00856.23 GAM21754.1 - 2.8e-07 30.9 0.0 2.2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.23 GAM21754.1 - 8.4e-05 22.0 0.1 0.11 12.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat FYVE PF01363.16 GAM21754.1 - 8.6e-05 22.3 12.0 0.0056 16.5 2.1 2.5 2 0 0 2 2 2 2 FYVE zinc finger TPR_17 PF13431.1 GAM21754.1 - 0.0027 17.7 0.1 0.034 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21754.1 - 0.0056 16.5 1.4 0.42 10.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM21754.1 - 0.0092 16.0 0.3 0.027 14.5 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21754.1 - 0.011 16.0 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21754.1 - 0.012 15.5 0.1 0.33 10.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21754.1 - 0.022 14.5 0.2 1.7 8.6 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21754.1 - 0.12 13.0 0.1 1.3 9.8 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Cript PF10235.4 GAM21754.1 - 1.1 9.6 9.9 1.3 9.4 1.6 2.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT HypA PF01155.14 GAM21754.1 - 1.8 8.3 11.9 5.7 6.6 0.6 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family NOB1_Zn_bind PF08772.6 GAM21754.1 - 5 7.0 12.8 7.3 6.5 1.3 2.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TPR_11 PF13414.1 GAM21755.1 - 0.00052 19.6 0.1 0.52 9.9 0.1 2.4 1 1 0 2 2 2 2 TPR repeat Mer2 PF09074.5 GAM21755.1 - 0.0063 16.4 0.2 0.0089 15.9 0.1 1.1 1 0 0 1 1 1 1 Mer2 TPR_1 PF00515.23 GAM21755.1 - 0.053 13.1 0.1 5.6 6.7 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21755.1 - 0.066 13.1 0.1 1.3 8.9 0.0 2.6 2 2 1 3 3 3 0 Tetratricopeptide repeat RD3 PF14473.1 GAM21755.1 - 0.092 12.2 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 RD3 protein SET PF00856.23 GAM21756.1 - 4e-08 33.7 0.1 6.5e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 SET domain TPR_12 PF13424.1 GAM21756.1 - 0.00015 21.6 2.1 0.02 14.8 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21756.1 - 0.0012 19.0 0.2 0.26 11.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-TFIIB PF13453.1 GAM21756.1 - 0.014 14.5 2.8 1.3 8.2 0.1 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger TPR_2 PF07719.12 GAM21756.1 - 0.061 13.2 1.3 13 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Imm5 PF14423.1 GAM21756.1 - 1.2 8.6 4.6 7.2 6.1 0.1 2.7 3 0 0 3 3 3 0 Immunity protein Imm5 Acetone_carb_G PF08882.6 GAM21756.1 - 1.3 9.0 5.3 2 8.4 0.1 3.3 4 0 0 4 4 4 0 Acetone carboxylase gamma subunit DUF1610 PF07754.6 GAM21756.1 - 4.4 7.5 12.2 8.6 6.5 2.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) FNIP PF05725.7 GAM21757.1 - 7.7e-27 92.9 20.5 1.7e-09 37.4 0.1 7.1 5 2 2 7 7 7 5 FNIP Repeat Antistasin PF02822.9 GAM21757.1 - 0.2 11.9 0.3 0.37 11.1 0.2 1.4 1 0 0 1 1 1 0 Antistasin family SET PF00856.23 GAM21758.1 - 6.2e-06 26.6 6.6 1.1e-05 25.8 2.1 2.7 2 1 0 2 2 2 1 SET domain Acetone_carb_G PF08882.6 GAM21758.1 - 0.012 15.6 0.1 0.031 14.2 0.1 1.7 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Ded_cyto PF06920.8 GAM21758.1 - 0.023 14.0 0.2 0.047 12.9 0.1 1.5 1 0 0 1 1 1 0 Dedicator of cytokinesis PRP1_N PF06424.7 GAM21758.1 - 0.18 12.1 0.1 0.18 12.1 0.1 1.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DZR PF12773.2 GAM21758.1 - 0.74 9.6 11.2 0.81 9.5 2.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAM21758.1 - 1.1 8.8 7.5 0.3 10.6 2.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 GAM21758.1 - 2.5 7.7 11.7 3.4 7.3 0.5 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 GAM21759.1 - 5.1e-17 61.5 10.4 5.1e-17 61.5 7.2 2.3 2 1 0 2 2 2 1 FYVE zinc finger Arrestin_N PF00339.24 GAM21759.1 - 2.1e-14 53.5 2.8 1.7e-11 44.1 0.1 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAM21759.1 - 2.6e-14 53.4 0.3 2e-12 47.3 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain FYVE_2 PF02318.11 GAM21759.1 - 0.0066 16.3 5.0 0.0066 16.3 3.5 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger LDB19 PF13002.2 GAM21759.1 - 0.0068 15.9 0.1 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like Rgp1 PF08737.5 GAM21759.1 - 0.049 12.7 0.1 0.18 10.8 0.0 1.8 1 1 1 2 2 2 0 Rgp1 Ank_2 PF12796.2 GAM21760.1 - 3.5e-10 40.0 0.1 0.0085 16.4 0.0 7.4 6 2 0 6 6 6 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM21760.1 - 0.00059 19.9 0.4 5.1 7.5 0.0 6.2 7 0 0 7 7 7 1 Ankyrin repeats (many copies) DUF366 PF04017.7 GAM21760.1 - 0.016 14.5 3.4 0.021 14.1 0.4 2.7 4 0 0 4 4 4 0 Domain of unknown function (DUF366) BolA PF01722.13 GAM21760.1 - 0.052 13.5 0.2 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 BolA-like protein FNIP PF05725.7 GAM21761.1 - 3.2e-16 59.0 14.1 2e-08 34.0 0.3 7.1 5 2 2 7 7 7 4 FNIP Repeat F-box PF00646.28 GAM21761.1 - 0.47 10.1 5.1 0.81 9.4 0.5 3.3 3 1 0 4 4 4 0 F-box domain FNIP PF05725.7 GAM21762.1 - 1.9e-08 34.0 9.6 2e-05 24.4 0.1 5.2 4 1 1 5 5 5 2 FNIP Repeat Corona_7 PF02398.11 GAM21762.1 - 0.074 13.5 0.7 0.14 12.6 0.5 1.5 1 0 0 1 1 1 0 Coronavirus protein 7 DotA PF11388.3 GAM21763.1 - 0.045 13.8 0.1 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Phagosome trafficking protein DotA SurA_N_3 PF13624.1 GAM21763.1 - 0.071 13.0 0.1 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 SurA N-terminal domain FNIP PF05725.7 GAM21764.1 - 2.5e-25 88.1 23.7 2.7e-13 49.6 0.6 7.1 5 2 4 9 9 9 7 FNIP Repeat FNIP PF05725.7 GAM21765.1 - 2.7e-20 72.0 31.1 1.1e-11 44.5 1.5 7.3 6 1 1 7 7 7 6 FNIP Repeat FNIP PF05725.7 GAM21766.1 - 8.1e-24 83.3 17.8 1.9e-11 43.7 0.8 7.6 5 2 4 9 9 9 6 FNIP Repeat F-box-like PF12937.2 GAM21766.1 - 0.076 12.7 0.1 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like FNIP PF05725.7 GAM21767.1 - 8.5e-43 144.0 19.9 5.2e-15 55.1 0.8 7.1 7 0 0 7 7 7 6 FNIP Repeat PSI PF01437.20 GAM21768.1 - 2.5e-05 24.3 11.9 4.4e-05 23.5 8.3 1.4 1 0 0 1 1 1 1 Plexin repeat FAM163 PF15069.1 GAM21768.1 - 0.0018 18.8 0.3 0.0018 18.8 0.2 2.1 2 0 0 2 2 2 1 FAM163 family IncA PF04156.9 GAM21768.1 - 0.0032 17.0 0.0 0.0042 16.7 0.0 1.1 1 0 0 1 1 1 1 IncA protein gpUL132 PF11359.3 GAM21768.1 - 0.093 12.0 1.4 0.098 11.9 1.0 1.2 1 1 0 1 1 1 0 Glycoprotein UL132 Baculo_11_kDa PF06143.6 GAM21768.1 - 0.11 11.8 0.6 0.19 11.1 0.4 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.1 GAM21768.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Prominin PF05478.6 GAM21768.1 - 0.41 8.1 7.4 0.54 7.7 5.2 1.1 1 0 0 1 1 1 0 Prominin Herpes_BLLF1 PF05109.8 GAM21768.1 - 0.51 8.2 5.0 1.2 7.0 0.9 2.0 2 0 0 2 2 2 0 Herpes virus major outer envelope glycoprotein (BLLF1) Orthoreo_P10 PF07204.6 GAM21768.1 - 1 9.1 13.2 9.8 5.9 9.1 2.0 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Ank_2 PF12796.2 GAM21769.1 - 6.5e-16 58.4 4.5 0.0049 17.1 0.0 7.4 6 2 0 7 7 7 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM21769.1 - 4.5e-09 36.2 5.3 4.5 7.6 0.0 8.6 7 3 4 11 11 11 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM21769.1 - 3.1e-08 33.8 13.9 0.22 12.1 0.0 7.7 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21769.1 - 2.5e-07 30.2 9.7 6.1 7.3 0.0 9.2 12 0 0 12 12 12 3 Ankyrin repeat Ank PF00023.25 GAM21769.1 - 0.0017 18.0 8.3 4.9 7.1 0.0 7.5 9 0 0 9 9 9 1 Ankyrin repeat Cpn60_TCP1 PF00118.19 GAM21770.1 - 1.2e-103 347.4 1.0 1.4e-103 347.1 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF956 PF06115.6 GAM21770.1 - 0.0075 15.8 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF956) TP_methylase PF00590.15 GAM21771.1 - 1.7e-19 70.3 0.0 3.2e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ras PF00071.17 GAM21772.1 - 1.8e-47 160.7 0.0 2.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21772.1 - 2.7e-15 56.9 0.0 4e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM21772.1 - 2.3e-06 26.9 0.0 3.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM21772.1 - 0.024 14.5 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 GAM21772.1 - 0.042 13.3 0.0 4.9 6.6 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 GAM21772.1 - 0.098 12.0 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Clp1 PF06807.9 GAM21773.1 - 5.8e-46 156.7 0.0 8.9e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 GAM21773.1 - 3.9e-14 52.5 0.0 6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 GAM21773.1 - 0.01 16.6 0.1 0.028 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM21773.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 GAM21773.1 - 0.033 14.4 0.3 0.079 13.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM21773.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 GAM21773.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM21773.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 GAM21773.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain LIM PF00412.17 GAM21774.1 - 4.3e-59 196.4 45.5 9.1e-16 57.6 3.9 4.0 4 0 0 4 4 4 4 LIM domain zf-BED PF02892.10 GAM21774.1 - 0.21 11.4 0.1 1.6 8.5 0.0 7.5 5 3 3 8 8 8 0 BED zinc finger WRC PF08879.5 GAM21774.1 - 0.48 10.1 5.1 1.2 8.8 0.1 3.7 3 0 0 3 3 3 0 WRC Lipoprotein_15 PF03640.10 GAM21774.1 - 1 8.8 4.9 14 5.1 0.0 3.8 4 0 0 4 4 4 0 Secreted repeat of unknown function PPR_2 PF13041.1 GAM21776.1 - 9.2e-08 31.9 9.6 0.018 15.0 0.0 7.5 8 0 0 8 8 8 2 PPR repeat family PPR PF01535.15 GAM21776.1 - 7.3e-05 22.4 0.8 8.8 6.5 0.0 6.0 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 GAM21776.1 - 0.0015 18.9 0.0 11 6.9 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat PPR_3 PF13812.1 GAM21776.1 - 0.0016 18.5 1.1 9.5 6.7 0.0 5.8 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Mem_trans PF03547.13 GAM21776.1 - 0.03 12.6 0.2 0.046 11.9 0.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Sel1 PF08238.7 GAM21776.1 - 0.077 13.6 1.8 1.7 9.4 0.1 3.3 3 0 0 3 3 3 0 Sel1 repeat rRNA_proc-arch PF13234.1 GAM21777.1 - 2.9e-74 249.6 1.5 6.2e-74 248.5 1.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 GAM21777.1 - 5.2e-57 191.9 0.0 1.6e-56 190.4 0.0 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 GAM21777.1 - 1.5e-21 76.6 0.1 6.3e-21 74.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM21777.1 - 3.7e-05 23.4 0.0 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2514 PF10721.4 GAM21777.1 - 1.7 8.3 5.5 3.1 7.4 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Kelch_4 PF13418.1 GAM21778.1 - 4.1e-11 42.4 7.1 3.7e-06 26.6 0.0 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM21778.1 - 5.7e-10 38.9 10.5 0.00084 19.4 0.0 5.4 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM21778.1 - 9.3e-10 38.4 3.6 0.0014 18.7 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM21778.1 - 1.2e-09 37.5 11.7 6.5e-06 25.5 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 GAM21778.1 - 2.4e-06 27.0 6.6 0.22 11.3 0.0 5.6 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM21778.1 - 0.1 12.5 10.5 1 9.3 0.3 5.4 7 0 0 7 7 7 0 Kelch motif Cnd2 PF05786.9 GAM21779.1 - 0.0028 16.2 3.8 0.0041 15.6 2.6 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 Nop14 PF04147.7 GAM21779.1 - 0.0053 14.7 5.4 0.0069 14.3 3.7 1.2 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 GAM21779.1 - 0.36 10.3 7.5 0.64 9.5 5.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 GAM21779.1 - 1.7 7.0 12.2 2.6 6.3 8.5 1.3 1 0 0 1 1 1 0 Daxx Family SSP160 PF06933.6 GAM21779.1 - 2.8 5.8 17.5 3.7 5.4 12.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.6 GAM21779.1 - 4.5 6.9 12.1 7 6.3 8.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus CDC45 PF02724.9 GAM21779.1 - 4.7 5.1 10.9 6.6 4.6 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 GAM21779.1 - 5.1 5.0 8.3 7.5 4.5 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-Di19 PF05605.7 GAM21780.1 - 0.031 14.3 2.2 0.031 14.3 1.5 3.6 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding EGF_CA PF07645.10 GAM21780.1 - 3 7.8 8.8 15 5.6 0.2 2.9 2 0 0 2 2 2 0 Calcium-binding EGF domain Kelch_3 PF13415.1 GAM21781.1 - 1.4e-13 50.5 0.5 0.034 14.3 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM21781.1 - 2.7e-13 49.4 3.3 0.0015 18.5 0.0 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM21781.1 - 6.1e-12 45.1 2.8 0.00038 20.1 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM21781.1 - 8.6e-10 38.0 2.4 0.014 14.9 0.1 4.7 4 0 0 4 4 4 3 Kelch motif zf-B_box PF00643.19 GAM21781.1 - 1.2e-07 31.4 11.5 2.9e-07 30.2 8.0 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_5 PF13854.1 GAM21781.1 - 3.5e-07 30.0 1.1 0.054 13.4 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM21781.1 - 0.00012 21.6 0.8 0.87 9.4 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Baculo_PEP_C PF04513.7 GAM21781.1 - 0.00087 19.1 1.8 0.002 17.9 1.3 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM21781.1 - 0.13 12.0 1.9 0.71 9.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IBR PF01485.16 GAM21781.1 - 0.54 10.1 4.3 1.4 8.8 3.0 1.6 1 0 0 1 1 1 0 IBR domain C1_3 PF07649.7 GAM21781.1 - 1.8 8.6 7.9 3.3 7.8 5.5 1.5 1 0 0 1 1 1 0 C1-like domain ArfGap PF01412.13 GAM21781.1 - 8.1 6.2 9.5 8.9 6.1 5.5 2.0 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Kelch_6 PF13964.1 GAM21782.1 - 1.5e-17 62.9 5.3 9.1e-05 22.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM21782.1 - 2e-10 40.2 11.1 2.8e-05 23.7 0.0 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21782.1 - 6.4e-10 38.9 0.6 0.72 10.0 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM21782.1 - 6.7e-06 25.9 4.2 0.031 14.2 0.3 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 GAM21782.1 - 6.7e-06 25.6 9.7 0.006 16.3 0.0 4.8 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 GAM21782.1 - 0.00086 18.8 11.8 1.1 8.9 0.0 5.4 6 0 0 6 6 6 2 Kelch motif ATP_sub_h PF10775.4 GAM21782.1 - 0.099 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h Kelch_6 PF13964.1 GAM21784.1 - 1.4e-09 37.7 6.8 0.0062 16.6 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM21784.1 - 3.5e-06 26.6 10.1 0.00069 19.3 0.1 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21784.1 - 4.7e-06 26.6 3.4 12 6.2 0.1 5.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM21784.1 - 0.011 15.7 11.4 1.3 9.0 0.2 3.9 3 1 0 3 3 3 0 Kelch motif Kelch_1 PF01344.20 GAM21784.1 - 0.038 13.5 5.7 8 6.0 0.0 4.3 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 GAM21784.1 - 0.098 12.4 8.0 0.98 9.2 0.1 3.8 4 1 0 4 4 4 0 Kelch motif 6PF2K PF01591.13 GAM21785.1 - 4.4e-64 215.5 1.0 7.3e-64 214.8 0.7 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAM21785.1 - 2.5e-24 86.1 1.9 4.7e-23 82.0 0.0 2.7 3 1 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAM21785.1 - 5.4e-07 29.5 0.0 5.4e-07 29.5 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAM21785.1 - 0.00012 22.8 0.0 0.0015 19.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM21785.1 - 0.0029 16.7 0.0 0.0062 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 GAM21785.1 - 0.024 13.8 0.0 0.024 13.8 0.0 2.1 2 1 0 3 3 3 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 GAM21785.1 - 0.071 13.4 0.0 0.72 10.1 0.0 2.5 1 1 2 3 3 3 0 AAA domain Abhydrolase_6 PF12697.2 GAM21787.1 - 5.2e-05 23.2 0.1 0.00013 21.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM21787.1 - 0.024 14.1 0.4 0.043 13.3 0.3 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Tmemb_185A PF10269.4 GAM21788.1 - 5.4e-27 94.9 30.4 1.3e-25 90.3 14.9 1.7 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF4521 PF15021.1 GAM21788.1 - 0.11 12.0 0.8 0.17 11.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Pkinase_Tyr PF07714.12 GAM21790.1 - 6.1e-64 215.5 0.0 8.9e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM21790.1 - 4.5e-54 183.3 0.1 1.3e-53 181.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 GAM21790.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM21790.1 - 0.0084 15.1 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAM21790.1 - 0.0098 14.7 0.1 0.024 13.4 0.1 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 TIG PF01833.19 GAM21791.1 - 9.7e-09 35.1 24.0 1e-07 31.8 3.7 3.9 2 1 1 3 3 3 3 IPT/TIG domain GPI-anchored PF10342.4 GAM21791.1 - 0.17 12.3 3.0 0.85 10.1 0.3 3.0 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Proteasome PF00227.21 GAM21792.1 - 1.5e-58 197.2 0.4 2.3e-58 196.6 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM21792.1 - 4.8e-14 51.3 0.1 9.6e-14 50.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Phosphodiest PF01663.17 GAM21793.1 - 1.7e-07 30.9 0.1 3.4e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Renin_r PF07850.9 GAM21793.1 - 0.0019 18.5 1.7 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 Renin receptor-like protein DUF2897 PF11446.3 GAM21793.1 - 4.4 7.1 8.7 0.14 12.0 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) PAP_assoc PF03828.14 GAM21794.1 - 3.6e-15 55.6 0.5 1.4e-14 53.8 0.3 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAM21794.1 - 6.1e-07 29.6 2.6 1.4e-06 28.5 0.0 2.9 2 1 0 2 2 2 1 Nucleotidyltransferase domain Kelch_6 PF13964.1 GAM21796.1 - 4.2e-11 42.5 8.2 0.0043 17.1 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM21796.1 - 7.7e-10 38.3 7.7 0.00026 20.6 0.0 5.4 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21796.1 - 1.4e-06 28.2 4.6 0.1 12.8 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM21796.1 - 7.1e-05 22.2 2.2 3.3 7.3 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM21796.1 - 0.016 15.1 4.8 4.5 7.3 0.1 3.7 3 0 0 3 3 3 0 Kelch motif LOH1CR12 PF10158.4 GAM21796.1 - 0.56 9.9 6.3 3 7.6 0.3 3.1 2 1 1 3 3 3 0 Tumour suppressor protein TPR_19 PF14559.1 GAM21797.1 - 5.6e-12 45.8 0.4 0.00074 19.8 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21797.1 - 2.1e-09 36.9 0.6 0.0059 16.2 0.0 4.2 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.1 GAM21797.1 - 5.7e-09 36.4 0.1 1.5 9.5 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM21797.1 - 3.5e-06 27.1 5.5 1.8 9.1 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21797.1 - 5.7e-06 25.8 0.3 0.083 12.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21797.1 - 6e-06 26.4 0.2 1 10.2 0.0 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21797.1 - 1.6e-05 24.7 8.7 0.031 14.2 0.2 4.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21797.1 - 1.9e-05 24.1 3.7 0.26 11.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21797.1 - 0.0001 21.7 0.3 1.4 8.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21797.1 - 0.0012 18.8 4.8 0.86 9.9 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM21797.1 - 0.0083 16.0 4.6 0.54 10.2 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM21797.1 - 0.14 12.2 0.3 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Kelch_6 PF13964.1 GAM21798.1 - 1.7e-09 37.4 5.0 0.016 15.3 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM21798.1 - 0.00081 18.8 0.7 0.2 11.2 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM21798.1 - 0.013 15.4 4.4 0.57 10.1 0.3 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 GAM21798.1 - 0.016 14.9 5.6 0.59 9.9 0.0 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain PQQ_3 PF13570.1 GAM21798.1 - 0.045 14.0 1.4 12 6.3 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain SnoaL PF07366.7 GAM21799.1 - 0.0029 17.1 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 GAM21799.1 - 0.0036 17.6 0.0 0.0043 17.4 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NAM PF02365.10 GAM21799.1 - 0.0091 16.1 0.3 0.0097 16.0 0.2 1.1 1 0 0 1 1 1 1 No apical meristem (NAM) protein DUF3596 PF12167.3 GAM21799.1 - 0.13 11.8 0.2 1.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3596) Ank_2 PF12796.2 GAM21800.1 - 9e-14 51.5 1.7 0.0021 18.3 0.0 5.1 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM21800.1 - 0.00023 21.2 3.5 2.8 8.3 0.1 5.9 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21800.1 - 0.00036 20.5 5.3 44 4.7 0.0 8.2 10 0 0 10 10 10 0 Ankyrin repeat Ank_4 PF13637.1 GAM21800.1 - 0.0087 16.5 6.6 13 6.4 0.0 6.7 5 3 4 9 9 9 1 Ankyrin repeats (many copies) DUF1955 PF09205.5 GAM21800.1 - 0.025 14.1 0.2 0.079 12.4 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Ank PF00023.25 GAM21800.1 - 0.035 13.9 7.1 20 5.2 0.1 7.0 9 0 0 9 9 9 0 Ankyrin repeat HEAT_2 PF13646.1 GAM21801.1 - 2.8e-06 27.4 0.0 0.058 13.6 0.0 5.2 2 2 3 5 5 5 2 HEAT repeats Arm PF00514.18 GAM21801.1 - 0.00063 19.4 10.2 1.2 9.1 0.0 6.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAM21801.1 - 0.015 15.7 1.4 3.4 8.2 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat DUF3651 PF12371.3 GAM21802.1 - 2.6e-07 30.5 15.4 1.7e-05 24.7 0.1 7.5 6 0 0 6 6 6 2 Protein of unknown function (DUF3651) DUF1573 PF07610.6 GAM21802.1 - 0.042 13.4 1.2 10 5.8 0.0 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1573) Kelch_1 PF01344.20 GAM21803.1 - 1.5e-47 158.9 13.6 4.9e-09 35.6 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM21803.1 - 7e-47 155.7 3.9 4.9e-08 32.8 0.0 6.5 2 1 4 6 6 6 6 Kelch motif Kelch_4 PF13418.1 GAM21803.1 - 6.2e-38 128.3 0.2 7e-08 32.1 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21803.1 - 4.8e-23 80.7 0.0 0.001 19.1 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM21803.1 - 2e-19 69.0 11.5 0.0008 19.3 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM21803.1 - 3.5e-13 48.7 4.9 0.00015 21.3 0.1 6.5 6 0 0 6 6 6 3 Kelch motif zf-B_box PF00643.19 GAM21803.1 - 2.9e-06 27.0 4.6 4.9e-06 26.3 3.2 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF3439 PF11921.3 GAM21803.1 - 0.014 15.1 8.4 0.04 13.6 5.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF234 PF03008.9 GAM21803.1 - 0.098 12.7 1.5 0.23 11.6 0.2 2.1 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function DUF2085 PF09858.4 GAM21803.1 - 0.15 12.1 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) Mucin PF01456.12 GAM21803.1 - 0.19 11.5 15.2 0.44 10.3 10.6 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein CKS PF01111.14 GAM21804.1 - 3.3e-33 113.3 0.1 3.7e-33 113.1 0.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit UPF0113 PF03657.8 GAM21805.1 - 3.6e-08 33.2 0.0 4.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 GAM21805.1 - 0.041 13.9 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 GAM21805.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PUA domain DUF835 PF05763.7 GAM21805.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF835) Ribosomal_L36e PF01158.13 GAM21806.1 - 2e-33 114.2 4.7 2.2e-33 114.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DKCLD PF08068.7 GAM21806.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 DKCLD (NUC011) domain Thioredoxin PF00085.15 GAM21807.1 - 1.2e-17 63.4 0.0 2.6e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin SpoIIIAH PF12685.2 GAM21807.1 - 0.0033 16.9 12.4 0.088 12.2 0.0 2.1 2 0 0 2 2 2 1 SpoIIIAH-like protein Thioredoxin_6 PF13848.1 GAM21807.1 - 0.0046 16.7 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM21807.1 - 0.017 15.1 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Hid1 PF12722.2 GAM21807.1 - 0.15 9.6 10.1 0.23 9.0 7.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Thioredoxin_2 PF13098.1 GAM21807.1 - 0.16 12.1 8.4 3.8 7.7 5.8 3.0 1 1 0 1 1 1 0 Thioredoxin-like domain DUF4366 PF14283.1 GAM21807.1 - 0.17 11.2 5.2 1.1 8.6 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2360 PF10152.4 GAM21807.1 - 0.22 11.8 0.2 0.22 11.8 0.1 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Tim54 PF11711.3 GAM21807.1 - 0.62 8.5 12.5 0.095 11.2 6.1 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Baculo_PP31 PF05311.6 GAM21807.1 - 0.88 8.7 9.8 0.31 10.2 4.3 1.9 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Neur_chan_memb PF02932.11 GAM21807.1 - 0.97 9.2 9.8 2.1 8.1 6.8 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.1 GAM21807.1 - 1.5 9.0 9.3 0.21 11.9 3.9 1.6 2 0 0 2 2 2 0 AAA domain Peptidase_S15 PF02129.13 GAM21807.1 - 1.7 8.0 9.3 0.92 8.8 4.4 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AUX_IAA PF02309.11 GAM21807.1 - 1.8 8.2 14.3 0.11 12.2 5.2 2.0 2 0 0 2 2 2 0 AUX/IAA family PAT1 PF09770.4 GAM21807.1 - 2.8 6.0 70.6 0.29 9.3 33.9 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 YjgP_YjgQ PF03739.9 GAM21807.1 - 3.4 6.2 6.5 1.5 7.4 2.7 1.7 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family FAM60A PF15396.1 GAM21807.1 - 4.4 7.0 9.9 8.1 6.1 6.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF1183 PF06682.7 GAM21807.1 - 4.4 6.8 15.2 16 5.0 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) GRP PF07172.6 GAM21807.1 - 4.7 7.7 5.4 6.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Glycine rich protein family DUF2201_N PF13203.1 GAM21807.1 - 5.3 6.1 17.3 0.053 12.6 6.9 1.4 2 0 0 2 2 1 0 Putative metallopeptidase domain SHR3_chaperone PF08229.6 GAM21807.1 - 5.3 5.9 11.1 4.8 6.0 5.9 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 Arf PF00025.16 GAM21808.1 - 2.4e-65 218.9 0.1 2.8e-65 218.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM21808.1 - 5.2e-13 48.6 0.0 6.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM21808.1 - 2.3e-09 36.7 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM21808.1 - 5e-09 35.6 0.0 6.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM21808.1 - 4.7e-08 32.1 0.6 8.9e-06 24.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 GAM21808.1 - 1.4e-05 25.5 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM21808.1 - 5.9e-05 22.9 0.0 0.00024 21.0 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase GST_C PF00043.20 GAM21809.1 - 4e-14 52.3 0.1 7e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM21809.1 - 6.7e-10 39.0 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM21809.1 - 1.2e-08 34.7 0.5 2.9e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM21809.1 - 1.8e-08 34.2 0.0 4.8e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM21809.1 - 2.5e-08 34.0 0.0 7.6e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM21809.1 - 3.5e-07 30.6 0.1 5.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Thiolase_N PF00108.18 GAM21810.1 - 8.4e-93 310.1 1.5 1.2e-92 309.6 1.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM21810.1 - 4.7e-45 151.9 1.9 3.4e-44 149.2 0.9 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM21810.1 - 2.4e-05 23.9 0.4 0.00031 20.2 0.4 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM21810.1 - 0.01 15.6 0.0 7.4 6.4 0.0 2.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain HIRA_B PF09453.5 GAM21811.1 - 0.01 15.3 0.1 0.079 12.5 0.0 2.6 2 0 0 2 2 2 0 HIRA B motif PRKCSH PF07915.8 GAM21812.1 - 1e-13 51.8 0.1 1e-13 51.8 0.1 2.9 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein CIMR PF00878.13 GAM21812.1 - 0.025 14.3 0.1 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat DUF2633 PF11119.3 GAM21812.1 - 0.08 12.6 0.1 0.08 12.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2633) Ycf1 PF05758.7 GAM21812.1 - 0.37 8.4 7.2 0.48 8.0 5.0 1.1 1 0 0 1 1 1 0 Ycf1 Shisa PF13908.1 GAM21812.1 - 0.62 10.2 8.8 0.19 11.8 3.1 2.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.11 GAM21812.1 - 0.76 9.6 5.3 1.2 8.9 3.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 GAM21812.1 - 0.84 7.7 5.3 1.2 7.2 3.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4045 PF13254.1 GAM21812.1 - 1.6 7.9 11.6 2.2 7.4 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ndc1_Nup PF09531.5 GAM21812.1 - 3 6.1 5.5 3.9 5.7 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GAGA_bind PF06217.7 GAM21812.1 - 6.6 6.6 13.6 10 6.0 9.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ank_2 PF12796.2 GAM21813.1 - 2.3e-27 95.1 6.4 6.1e-09 36.1 2.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM21813.1 - 2.1e-19 69.5 7.9 5e-05 23.6 0.1 7.7 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM21813.1 - 2.5e-19 68.8 11.2 0.011 15.9 0.5 9.5 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.25 GAM21813.1 - 1e-16 59.7 9.2 0.16 11.8 0.1 9.4 9 1 1 10 10 10 7 Ankyrin repeat Ank_3 PF13606.1 GAM21813.1 - 1.7e-14 52.5 10.8 0.06 13.6 0.0 9.7 6 2 4 10 10 10 4 Ankyrin repeat Brr6_like_C_C PF10104.4 GAM21814.1 - 1.2e-34 118.7 3.8 2.1e-34 117.9 2.6 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CHORD PF04968.7 GAM21815.1 - 6.5e-50 167.2 21.1 9.7e-25 86.6 4.0 2.5 2 0 0 2 2 2 2 CHORD CS PF04969.11 GAM21815.1 - 8.5e-13 48.6 1.2 1.1e-12 48.2 0.3 1.6 2 0 0 2 2 2 1 CS domain Kelch_4 PF13418.1 GAM21816.1 - 3.1e-21 74.8 17.6 3.4e-08 33.1 0.1 6.8 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM21816.1 - 3.2e-20 71.3 15.5 2e-09 37.2 0.0 6.8 5 2 1 6 6 6 4 Kelch motif Kelch_3 PF13415.1 GAM21816.1 - 2.2e-19 69.0 4.7 5.6e-09 35.9 0.0 7.3 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM21816.1 - 6.8e-18 64.2 9.6 4.5e-06 26.4 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 GAM21816.1 - 2.8e-17 61.9 14.0 4.2e-07 29.3 0.0 6.4 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAM21816.1 - 2.5e-12 46.0 17.7 3.3e-05 23.4 0.0 7.0 6 1 0 6 6 6 3 Kelch motif F-box-like PF12937.2 GAM21816.1 - 1.1e-07 31.4 0.4 2.6e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM21816.1 - 7.7e-06 25.4 2.2 1.6e-05 24.3 1.5 1.6 1 0 0 1 1 1 1 F-box domain Tir_receptor_N PF07490.6 GAM21816.1 - 0.26 10.8 3.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus SR-25 PF10500.4 GAM21816.1 - 7.2 6.0 12.2 13 5.1 8.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SQS_PSY PF00494.14 GAM21817.1 - 7.9e-34 117.1 0.0 9e-32 110.4 0.0 2.1 1 1 0 1 1 1 1 Squalene/phytoene synthase Sulfate_tra_GLY PF13792.1 GAM21817.1 - 0.059 13.0 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Spc7_N PF15402.1 GAM21818.1 - 1.3 6.9 6.3 1.7 6.5 4.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MSA-2c PF12238.3 GAM21818.1 - 2.1 7.9 11.6 3.2 7.3 8.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF605 PF04652.11 GAM21818.1 - 2.4 7.4 10.0 3.2 7.0 7.0 1.1 1 0 0 1 1 1 0 Vta1 like Atrophin-1 PF03154.10 GAM21818.1 - 2.8 5.9 13.0 3.9 5.5 9.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family PRCC PF10253.4 GAM21818.1 - 5 7.7 7.0 7.6 7.1 4.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting NARP1 PF12569.3 GAM21819.1 - 2.2e-133 445.7 21.7 6.5e-119 398.0 9.6 3.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 GAM21819.1 - 1.2e-15 56.5 0.1 5.3 7.9 0.0 9.9 7 3 4 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21819.1 - 4.2e-13 48.7 18.0 0.0058 16.2 0.0 7.5 7 1 1 8 8 8 4 TPR repeat TPR_19 PF14559.1 GAM21819.1 - 6.4e-13 48.8 8.0 0.0028 17.9 0.0 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21819.1 - 7e-10 38.0 22.4 9.7e-05 22.0 0.0 8.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21819.1 - 1e-09 38.1 13.5 0.0097 15.8 0.3 6.7 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM21819.1 - 8.5e-07 29.4 4.5 6.8 7.4 0.1 6.9 5 3 2 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21819.1 - 1.4e-05 24.4 17.4 0.002 17.6 0.0 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM21819.1 - 0.0013 19.0 10.7 1 10.0 0.1 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21819.1 - 0.0032 17.5 4.9 1.2 9.5 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM21819.1 - 0.011 15.4 8.0 10 6.1 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21819.1 - 0.039 13.7 10.4 12 5.9 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM21819.1 - 0.54 10.1 14.2 16 5.4 0.0 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat PIF1 PF05970.9 GAM21820.1 - 5.9e-61 206.4 0.1 2.2e-46 158.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 GAM21820.1 - 4.2e-21 75.4 0.0 7.2e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM21820.1 - 2.3e-08 34.2 0.0 6.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM21820.1 - 1.9e-05 24.3 2.0 2e-05 24.2 0.3 1.8 2 0 0 2 2 1 1 Part of AAA domain Herpes_Helicase PF02689.9 GAM21820.1 - 2.1e-05 22.5 0.0 0.0069 14.1 0.0 2.2 2 0 0 2 2 2 2 Helicase AAA_5 PF07728.9 GAM21820.1 - 7.5e-05 22.4 0.1 0.00028 20.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.1 GAM21820.1 - 0.00015 21.8 0.0 0.00039 20.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 GAM21820.1 - 0.00017 20.6 0.3 0.0016 17.4 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 GAM21820.1 - 0.00019 20.4 0.3 0.00031 19.7 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 GAM21820.1 - 0.00043 19.8 0.2 1.2 8.5 0.2 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 GAM21820.1 - 0.00055 19.4 0.3 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein PhoH PF02562.11 GAM21820.1 - 0.00065 18.9 0.1 0.0013 18.0 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.9 GAM21820.1 - 0.00072 19.2 4.0 0.0057 16.2 0.9 2.8 2 1 0 2 2 2 1 Helicase Arch_ATPase PF01637.13 GAM21820.1 - 0.0011 18.7 0.2 0.0027 17.4 0.1 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 GAM21820.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 GAM21820.1 - 0.0014 17.9 0.1 0.0069 15.7 0.1 2.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 GAM21820.1 - 0.0035 17.3 0.0 0.0096 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 GAM21820.1 - 0.0045 15.6 0.1 0.0076 14.9 0.1 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 GAM21820.1 - 0.0045 16.7 0.1 1.2 8.8 0.0 2.9 3 0 0 3 3 2 1 NTPase Mg_chelatase PF01078.16 GAM21820.1 - 0.0049 16.0 0.1 0.0092 15.1 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 GAM21820.1 - 0.006 16.4 0.0 0.019 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM21820.1 - 0.0068 15.9 2.6 1.5 8.3 0.2 2.7 2 1 0 3 3 2 2 AAA domain AAA PF00004.24 GAM21820.1 - 0.0088 16.2 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 GAM21820.1 - 0.019 14.0 1.5 0.14 11.2 0.1 2.6 3 0 0 3 3 3 0 KaiC RNA_helicase PF00910.17 GAM21820.1 - 0.023 14.8 0.0 0.11 12.6 0.0 2.2 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 GAM21820.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 GAM21820.1 - 0.068 14.0 0.2 0.21 12.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 GAM21820.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 GAM21820.1 - 0.075 13.0 0.0 0.56 10.2 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 GAM21820.1 - 0.081 12.3 0.1 0.081 12.3 0.1 1.8 3 0 0 3 3 1 0 Sigma-54 interaction domain DUF815 PF05673.8 GAM21820.1 - 0.088 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 GAM21820.1 - 0.096 12.9 0.1 0.37 11.0 0.0 1.9 1 1 0 2 2 1 0 ABC transporter PseudoU_synth_2 PF00849.17 GAM21821.1 - 2e-14 53.7 1.6 8.5e-14 51.7 0.0 2.7 2 2 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.20 GAM21821.1 - 1.5e-11 43.5 1.3 3.7e-11 42.2 0.1 2.3 2 1 1 3 3 3 1 S4 domain AAA_25 PF13481.1 GAM21821.1 - 0.0058 16.0 0.0 0.013 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain S4_2 PF13275.1 GAM21821.1 - 0.025 14.1 0.1 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 S4 domain FNIP PF05725.7 GAM21822.1 - 7.8e-56 185.8 4.3 4.6e-11 42.4 0.0 6.6 4 1 5 9 9 9 7 FNIP Repeat DUF1769 PF08588.5 GAM21822.1 - 0.00043 20.1 12.3 11 6.0 0.0 6.6 5 3 3 8 8 8 3 Protein of unknown function (DUF1769) SdpI PF13630.1 GAM21823.1 - 0.004 16.8 3.0 0.004 16.8 2.1 3.3 2 1 0 2 2 2 1 SdpI/YhfL protein family DEP PF00610.16 GAM21824.1 - 1.1e-35 121.1 4.9 4.8e-18 64.6 0.1 2.7 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 GAM21824.1 - 0.0025 17.9 0.1 0.0025 17.9 0.1 2.3 3 0 0 3 3 3 1 PH domain Pkinase PF00069.20 GAM21825.1 - 6.8e-64 215.5 0.0 1.6e-63 214.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21825.1 - 5.3e-44 150.2 0.0 9.2e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM21825.1 - 5.6e-06 25.5 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HALZ PF02183.13 GAM21825.1 - 0.0061 16.2 2.0 0.0089 15.7 0.5 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper FAM176 PF14851.1 GAM21826.1 - 4.3 6.9 5.1 6.9 6.3 3.6 1.3 1 0 0 1 1 1 0 FAM176 family GNT-I PF03071.10 GAM21827.1 - 5.5e-10 38.3 1.7 6.1e-10 38.2 0.6 1.4 2 0 0 2 2 2 1 GNT-I family Integrin_beta PF00362.13 GAM21828.1 - 0.0025 16.7 0.1 0.064 12.1 0.0 2.2 1 1 1 2 2 2 2 Integrin, beta chain FNIP PF05725.7 GAM21829.1 - 8.5e-26 89.6 18.6 2.7e-08 33.6 0.0 5.3 5 1 0 5 5 5 4 FNIP Repeat Tmemb_cc2 PF10267.4 GAM21830.1 - 0.012 14.2 0.1 0.012 14.2 0.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RabGAP-TBC PF00566.13 GAM21831.1 - 4e-47 160.4 3.3 1.6e-46 158.5 2.3 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 GAM21831.1 - 2.9e-13 48.0 2.0 5.8e-06 25.2 0.1 3.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAM21831.1 - 7.7e-11 40.9 1.9 0.00011 21.8 0.1 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM21831.1 - 1.4e-10 40.0 3.0 4.7e-05 22.5 0.3 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAM21831.1 - 1.3e-09 37.9 5.3 0.00068 19.7 0.3 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM21831.1 - 1.5e-05 24.5 6.1 0.0014 18.2 0.3 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 GAM21831.1 - 0.033 14.0 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Arf PF00025.16 GAM21832.1 - 9.2e-71 236.6 2.0 1e-70 236.4 1.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM21832.1 - 2e-12 46.7 0.1 2.4e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM21832.1 - 8.5e-11 41.1 4.8 2.2e-06 26.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM21832.1 - 1.5e-10 40.6 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM21832.1 - 1.4e-08 35.2 0.0 1.9e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM21832.1 - 1.7e-08 33.9 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM21832.1 - 3.6e-08 33.3 0.0 5.5e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM21832.1 - 6.4e-05 22.4 0.0 0.00025 20.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM21832.1 - 0.053 12.8 0.3 0.2 10.9 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.1 GAM21832.1 - 0.069 13.0 0.8 0.13 12.1 0.4 1.5 1 1 0 1 1 1 0 AAA domain ComX PF05952.7 GAM21832.1 - 0.13 11.8 0.2 0.69 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacillus competence pheromone ComX PduV-EutP PF10662.4 GAM21832.1 - 0.14 11.6 0.1 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF829 PF05705.9 GAM21833.1 - 7.2e-40 137.1 1.0 1.7e-39 135.9 0.7 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ribosomal_L38e PF01781.13 GAM21834.1 - 8.1e-27 92.7 1.5 9.2e-27 92.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family FimP PF09766.4 GAM21835.1 - 4.9e-44 150.8 9.5 9.7e-25 87.3 5.3 2.1 1 1 1 2 2 2 2 Fms-interacting protein Baculo_PEP_C PF04513.7 GAM21835.1 - 0.16 11.7 5.9 0.053 13.3 1.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.14 GAM21835.1 - 0.19 9.4 14.1 0.34 8.5 9.8 1.3 1 1 0 1 1 1 0 Myosin tail DUF4164 PF13747.1 GAM21835.1 - 0.21 11.7 13.0 0.26 11.4 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF948 PF06103.6 GAM21835.1 - 0.59 10.0 6.0 0.12 12.1 0.9 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 GAM21835.1 - 4.1 7.5 11.6 3.2 7.8 1.8 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil XhlA PF10779.4 GAM21835.1 - 8.4 6.3 8.0 0.48 10.3 0.8 2.4 2 1 0 2 2 2 0 Haemolysin XhlA HA2 PF04408.18 GAM21836.1 - 3.1e-19 68.8 0.0 3.1e-19 68.8 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAM21836.1 - 1.4e-16 60.2 0.0 4.3e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAM21836.1 - 5.7e-14 51.7 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM21836.1 - 5.3e-11 42.3 2.2 7.1e-10 38.6 0.1 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase RWD PF05773.17 GAM21836.1 - 1e-09 38.2 0.2 5.5e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 RWD domain AAA_22 PF13401.1 GAM21836.1 - 7.2e-06 26.1 0.1 2.8e-05 24.2 0.1 2.0 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 GAM21836.1 - 3.7e-05 23.9 0.9 8.6e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_19 PF13245.1 GAM21836.1 - 0.0026 17.4 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 GAM21836.1 - 0.016 14.1 0.1 0.016 14.1 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 GAM21836.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM21836.1 - 0.053 12.9 0.0 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain dsrm PF00035.20 GAM21836.1 - 0.14 12.7 1.1 0.33 11.5 0.1 2.3 2 0 0 2 2 1 0 Double-stranded RNA binding motif DUF4337 PF14235.1 GAM21837.1 - 7.2 6.4 14.3 0.39 10.5 5.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Ribosomal_L22 PF00237.14 GAM21838.1 - 4.1e-20 71.6 0.0 1.5e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Hph PF13694.1 GAM21838.1 - 0.0023 17.9 3.8 0.0034 17.4 2.6 1.2 1 0 0 1 1 1 1 Sec63/Sec62 complex-interacting family Mucin PF01456.12 GAM21838.1 - 0.1 12.3 11.7 0.15 11.8 8.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 GAM21838.1 - 2.7 5.6 5.8 3.3 5.3 4.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LIM PF00412.17 GAM21839.1 - 7.1e-12 45.2 5.8 1.5e-11 44.1 4.0 1.6 1 0 0 1 1 1 1 LIM domain Med15 PF09606.5 GAM21839.1 - 2.1 6.4 23.5 2.4 6.2 16.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dymeclin PF09742.4 GAM21840.1 - 8e-79 265.5 21.7 9.5e-79 265.2 15.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ada3 PF10198.4 GAM21842.1 - 3.4e-12 46.2 9.4 3.4e-12 46.2 6.5 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Lzipper-MIP1 PF14389.1 GAM21842.1 - 0.016 15.2 3.1 0.028 14.4 0.5 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Y2_Tnp PF04986.8 GAM21842.1 - 0.42 10.3 2.8 0.37 10.5 0.4 2.0 2 0 0 2 2 2 0 Putative transposase PH PF00169.24 GAM21843.1 - 5.6e-09 36.1 0.7 2.1e-08 34.2 0.5 2.1 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 GAM21843.1 - 0.0064 16.5 0.7 0.0064 16.5 0.5 2.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 GAM21843.1 - 0.13 12.5 4.3 0.77 10.0 1.9 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Chorion_2 PF03964.10 GAM21843.1 - 0.22 12.0 5.0 4.5 7.8 0.4 2.6 2 0 0 2 2 2 0 Chorion family 2 Ribosomal_60s PF00428.14 GAM21843.1 - 2 8.8 5.9 8.9 6.7 0.8 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein IF4E PF01652.13 GAM21844.1 - 5.4e-53 178.9 1.6 7.9e-53 178.3 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tir_receptor_C PF07489.6 GAM21844.1 - 0.3 10.8 4.2 0.44 10.2 2.9 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Pex14_N PF04695.8 GAM21844.1 - 1.5 8.8 4.1 2.2 8.2 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GST_C PF00043.20 GAM21845.1 - 2.4e-11 43.4 0.0 4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM21845.1 - 2.8e-11 43.1 0.0 5.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM21845.1 - 5.2e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM21845.1 - 6.6e-10 39.0 0.0 1.6e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM21845.1 - 3.1e-09 36.8 0.0 4.2e-07 30.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM21845.1 - 2.2e-06 28.0 0.0 3.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3087 PF11286.3 GAM21845.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Malic_M PF03949.10 GAM21846.1 - 4.5e-94 314.7 0.0 6e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 GAM21846.1 - 1e-69 233.8 0.0 2.4e-69 232.5 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain 2-Hacid_dh_C PF02826.14 GAM21849.1 - 5.9e-49 165.6 0.0 1.3e-48 164.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM21849.1 - 2.7e-34 117.5 0.0 3.4e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 GAM21849.1 - 0.0022 17.4 0.1 2.9 7.4 0.0 2.8 2 0 0 2 2 2 2 ACT domain NAD_binding_2 PF03446.10 GAM21849.1 - 0.0023 17.8 0.1 0.0067 16.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.14 GAM21849.1 - 0.01 14.5 0.0 0.47 9.0 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase PAP2 PF01569.16 GAM21850.1 - 4.8e-11 42.4 8.0 4.8e-11 42.4 5.5 3.2 2 2 0 3 3 3 1 PAP2 superfamily WD40 PF00400.27 GAM21851.1 - 4e-28 96.2 11.1 3e-08 33.2 0.0 6.2 6 1 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_3 PF13920.1 GAM21851.1 - 7.2e-08 31.9 5.0 1.6e-07 30.8 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.2 GAM21851.1 - 2.1e-07 30.5 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like zf-C3HC4_2 PF13923.1 GAM21851.1 - 9.3e-07 28.7 10.4 3.2e-06 27.0 7.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM21851.1 - 1.1e-06 28.3 10.3 2.8e-06 27.0 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM21851.1 - 3.9e-06 26.4 9.4 3.9e-06 26.4 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM21851.1 - 9.5e-06 25.1 9.8 9.5e-06 25.1 6.8 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM21851.1 - 1.3e-05 24.9 11.8 3.3e-05 23.6 8.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING F-box PF00646.28 GAM21851.1 - 0.00015 21.2 0.1 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain zf-RING_UBOX PF13445.1 GAM21851.1 - 0.00017 21.1 8.2 0.0004 20.0 4.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger PQQ_2 PF13360.1 GAM21851.1 - 0.00027 20.4 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 GAM21851.1 - 0.0089 14.2 1.4 2.4 6.1 0.4 3.0 2 1 0 2 2 2 1 Nucleoporin Nup120/160 zf-RING_4 PF14570.1 GAM21851.1 - 0.032 13.8 4.2 0.11 12.1 2.9 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 GAM21851.1 - 0.033 13.9 2.6 0.077 12.7 1.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 GAM21851.1 - 0.042 13.6 2.7 0.099 12.4 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAM21851.1 - 1.8 8.6 7.2 4.3 7.5 5.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger ATP-synt PF00231.14 GAM21852.1 - 2.8e-58 197.5 0.4 3.2e-58 197.3 0.3 1.0 1 0 0 1 1 1 1 ATP synthase Proteasome PF00227.21 GAM21853.1 - 2.5e-48 163.8 0.2 2.9e-48 163.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit VPS9 PF02204.13 GAM21854.1 - 5e-14 52.1 1.0 1.3e-13 50.8 0.7 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1632 PF07857.7 GAM21856.1 - 2.3e-58 197.4 6.3 2.3e-58 197.4 4.4 2.0 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 GAM21856.1 - 2.2e-10 40.0 5.7 2.2e-10 40.0 3.9 2.8 2 2 0 2 2 2 1 Sugar transport protein DUF606 PF04657.8 GAM21856.1 - 0.012 15.6 13.8 0.012 15.6 9.5 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF606 NDUF_B12 PF08122.7 GAM21856.1 - 0.041 13.6 0.1 0.54 10.0 0.1 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Ank_2 PF12796.2 GAM21857.1 - 1.8e-09 37.7 4.1 0.1 12.9 0.1 7.4 5 3 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM21857.1 - 0.002 18.1 10.6 1.2e+02 3.3 0.1 10.5 13 0 0 13 13 13 0 Ankyrin repeat Lyase_1 PF00206.15 GAM21858.1 - 1.1e-115 386.1 0.0 1.5e-115 385.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 GAM21858.1 - 2.2e-26 91.6 0.0 5.9e-26 90.2 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus LSM PF01423.17 GAM21859.1 - 2e-12 46.4 0.3 4e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 LSM domain Cullin_binding PF03556.10 GAM21860.1 - 2.2e-33 114.8 0.8 2.2e-33 114.8 0.5 1.8 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 GAM21860.1 - 1.9e-11 43.3 0.0 5.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain EF-hand_7 PF13499.1 GAM21860.1 - 0.039 14.0 1.7 0.14 12.3 0.4 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 GAM21860.1 - 0.15 11.6 2.3 0.82 9.3 0.4 2.9 2 2 0 2 2 2 0 EF-hand domain pair Kelch_6 PF13964.1 GAM21861.1 - 3.5e-13 49.1 3.9 6.8e-08 32.3 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM21861.1 - 5.9e-10 38.7 4.0 0.00015 21.4 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21861.1 - 3.4e-05 23.8 0.4 1.2 9.3 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM21861.1 - 0.00029 20.3 6.4 0.038 13.5 0.1 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 GAM21861.1 - 0.0059 16.5 5.8 0.03 14.2 0.7 2.9 3 0 0 3 3 3 1 Kelch motif DUF848 PF05852.6 GAM21861.1 - 0.069 12.9 1.1 0.16 11.8 0.8 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Phosphoesterase PF04185.9 GAM21862.1 - 1.8e-30 106.4 7.3 1.2e-29 103.7 2.0 2.7 1 1 1 2 2 2 1 Phosphoesterase family DUF273 PF03314.9 GAM21862.1 - 0.071 12.4 0.1 0.095 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Kelch_6 PF13964.1 GAM21863.1 - 5.7e-20 70.5 2.7 8.7e-05 22.5 0.2 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM21863.1 - 9.6e-13 47.6 5.1 0.00011 21.8 0.0 4.0 4 0 0 4 4 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21863.1 - 2e-06 27.7 2.3 0.006 16.7 0.2 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM21863.1 - 6.6e-06 25.5 5.6 0.31 10.5 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAM21863.1 - 1e-05 25.0 5.7 0.12 12.1 0.0 4.4 5 0 0 5 5 4 2 Kelch motif Kelch_5 PF13854.1 GAM21863.1 - 0.00055 19.8 12.0 0.045 13.7 0.2 3.5 3 0 0 3 3 3 2 Kelch motif IMS_C PF11799.3 GAM21863.1 - 0.0061 16.4 1.0 2.1 8.2 0.1 2.6 2 0 0 2 2 2 2 impB/mucB/samB family C-terminal domain MS_channel PF00924.13 GAM21863.1 - 0.015 14.6 3.5 1.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel NYD-SP28 PF14772.1 GAM21863.1 - 0.015 15.3 11.6 3.1 7.9 0.0 5.1 5 0 0 5 5 5 0 Sperm tail Reprolysin PF01421.14 GAM21863.1 - 0.015 14.8 2.0 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease DUF848 PF05852.6 GAM21863.1 - 0.038 13.8 7.8 0.34 10.7 1.7 2.8 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HTH_AsnC-type PF13404.1 GAM21863.1 - 0.065 12.7 0.2 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain W2 PF02020.13 GAM21863.1 - 0.12 12.2 1.8 9.5 6.2 0.1 2.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon DUF2935 PF11155.3 GAM21863.1 - 3.8 7.6 14.8 3 7.9 0.1 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) ELMO_CED12 PF04727.8 GAM21864.1 - 2.6e-22 79.1 1.7 3.4e-22 78.8 0.1 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family Methyltransf_2 PF00891.13 GAM21864.1 - 0.00019 20.7 0.8 0.00067 18.9 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase Pkinase PF00069.20 GAM21866.1 - 2.9e-70 236.3 0.1 3.9e-70 235.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21866.1 - 2.1e-48 164.6 0.1 2.9e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 GAM21866.1 - 4.1e-17 62.2 0.1 9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PBD PF00786.23 GAM21866.1 - 3.2e-16 59.4 0.1 1e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.1 GAM21866.1 - 1.9e-07 31.2 0.9 3e-05 24.2 0.6 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 GAM21866.1 - 2.6e-05 23.3 0.1 0.00026 20.0 0.0 2.0 1 1 0 2 2 2 1 Kinase-like PH_9 PF15410.1 GAM21866.1 - 0.039 14.1 0.1 1.4 9.0 0.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.1 GAM21866.1 - 0.051 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain APH PF01636.18 GAM21866.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1356 PF07092.7 GAM21866.1 - 0.17 11.0 1.5 0.26 10.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Glycogen_syn PF05693.8 GAM21867.1 - 3.3e-270 897.8 0.0 4.1e-270 897.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 GAM21867.1 - 2.8e-06 26.8 0.0 0.0005 19.5 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 GAM21867.1 - 1.1e-05 25.1 1.7 1.3e-05 24.8 0.3 1.7 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 GAM21867.1 - 0.0021 18.2 0.0 0.0059 16.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain TRA-1_regulated PF02343.11 GAM21867.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 Pkinase PF00069.20 GAM21868.1 - 8.3e-79 264.3 0.0 2.2e-78 262.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM21868.1 - 5.7e-43 146.8 0.0 5.7e-43 146.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 GAM21868.1 - 2.4e-16 58.9 0.0 4.1e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 GAM21868.1 - 3.6e-06 26.1 0.0 7e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM21868.1 - 0.00029 20.6 0.0 0.0056 16.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM21868.1 - 0.00031 19.8 0.1 0.0012 17.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 GAM21868.1 - 0.0018 16.9 0.1 0.0038 15.8 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC UBA_2 PF08587.6 GAM21868.1 - 0.034 14.3 0.1 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) UBA PF00627.26 GAM21868.1 - 0.053 13.3 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain UBA_3 PF09288.5 GAM21868.1 - 0.16 11.6 0.1 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Laminin_EGF PF00053.19 GAM21869.1 - 0.053 13.4 31.5 0.093 12.6 5.3 3.5 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) UPF0172 PF03665.8 GAM21870.1 - 1.4e-46 158.4 0.3 1.6e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 GAM21870.1 - 0.00021 21.0 0.2 0.0003 20.4 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Vezatin PF12632.2 GAM21870.1 - 0.03 13.4 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF3689 PF12463.3 GAM21871.1 - 1.8e-19 69.6 5.2 2.9e-19 68.9 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3689) BAR PF03114.13 GAM21872.1 - 4.5e-11 42.7 4.2 4.5e-11 42.7 2.9 1.9 2 0 0 2 2 2 1 BAR domain DnaJ PF00226.26 GAM21872.1 - 0.00023 20.8 0.0 0.00069 19.2 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain NAD_binding_10 PF13460.1 GAM21873.1 - 9.3e-09 35.5 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM21873.1 - 1.3e-07 31.2 0.1 9.7e-07 28.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM21873.1 - 5.4e-05 22.5 0.0 9.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 GAM21873.1 - 0.0022 17.0 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 GAM21873.1 - 0.0043 17.5 0.1 0.015 15.8 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.12 GAM21873.1 - 0.0076 15.1 0.0 0.22 10.3 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_2 PF03446.10 GAM21873.1 - 0.0083 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 GAM21873.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.12 GAM21873.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glycos_transf_1 PF00534.15 GAM21874.1 - 3.1e-26 91.8 0.3 7.1e-26 90.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 GAM21874.1 - 1.9e-09 37.7 0.0 1.7e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2183 PF09949.4 GAM21874.1 - 0.005 16.7 0.3 3.4 7.6 0.0 2.7 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2183) Glyco_trans_1_2 PF13524.1 GAM21874.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF4131 PF13567.1 GAM21874.1 - 0.052 12.9 0.4 0.12 11.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) IRS PF02174.12 GAM21875.1 - 0.025 14.1 0.9 0.079 12.5 0.6 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) BRX PF08381.6 GAM21875.1 - 0.053 12.5 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 EBP PF05241.7 GAM21876.1 - 9e-44 148.8 13.2 1e-43 148.6 9.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2721 PF11026.3 GAM21876.1 - 5.4 6.6 9.8 0.3 10.7 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Paf1 PF03985.8 GAM21877.1 - 8.1e-45 153.3 8.4 8.1e-45 153.3 5.8 3.1 1 1 2 3 3 3 1 Paf1 Abhydrolase_5 PF12695.2 GAM21878.1 - 2e-10 40.5 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM21878.1 - 6.6e-05 22.7 0.0 0.0077 15.9 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 GAM21878.1 - 6.8e-05 22.8 0.0 7.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 GAM21878.1 - 0.002 17.4 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 GAM21878.1 - 0.082 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Orn_Arg_deC_N PF02784.11 GAM21879.1 - 7.1e-73 244.8 0.0 9.2e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAM21879.1 - 3.6e-32 110.5 0.0 8.9e-32 109.2 0.0 1.7 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 GAM21879.1 - 0.00063 19.0 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Folliculin PF11704.3 GAM21880.1 - 3.8e-36 124.2 0.0 9.9e-36 122.8 0.0 1.7 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Cyt_c_ox_IV PF12270.3 GAM21881.1 - 0.05 13.3 0.3 0.054 13.2 0.2 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Ran_BP1 PF00638.13 GAM21882.1 - 2.2e-44 150.3 0.4 3.2e-44 149.9 0.3 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 GAM21882.1 - 0.01 15.5 0.7 0.12 12.1 0.5 2.1 1 1 0 1 1 1 0 WH1 domain GET2 PF08690.5 GAM21882.1 - 0.066 12.4 1.6 0.094 11.9 1.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 MRI PF15325.1 GAM21882.1 - 8.3 7.4 8.2 2.9 8.8 3.0 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection SH3_9 PF14604.1 GAM21883.1 - 1.9e-18 65.7 0.1 4.3e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 GAM21883.1 - 2.9e-15 56.2 0.1 2.9e-15 56.2 0.1 3.1 2 2 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAM21883.1 - 1.1e-14 53.4 0.1 2.2e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM21883.1 - 1.1e-13 50.4 0.0 2.3e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Uds1 PF15456.1 GAM21883.1 - 0.0026 17.7 1.3 0.0026 17.7 0.9 3.3 2 1 1 3 3 3 1 Up-regulated During Septation GAS PF13851.1 GAM21883.1 - 0.019 14.1 27.5 0.16 11.1 10.5 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4613 PF15390.1 GAM21883.1 - 0.25 9.4 19.1 0.065 11.4 8.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) Spore_YtfJ PF09579.5 GAM21884.1 - 0.74 9.7 7.9 1.7 8.5 5.4 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Lectin_leg-like PF03388.8 GAM21885.1 - 1.1e-52 178.4 1.4 1.1e-52 178.4 1.0 1.6 2 0 0 2 2 2 1 Legume-like lectin family DUF2120 PF09893.4 GAM21885.1 - 0.0077 16.1 1.4 0.019 14.8 0.2 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2120) Med15 PF09606.5 GAM21885.1 - 0.013 13.7 54.0 0.016 13.4 37.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Baculo_p24 PF05073.7 GAM21885.1 - 0.03 13.8 0.5 0.03 13.8 0.4 3.0 3 1 0 3 3 3 0 Baculovirus P24 capsid protein Cellulose_synt PF03552.9 GAM21885.1 - 0.035 12.4 2.8 0.047 11.9 1.9 1.3 1 0 0 1 1 1 0 Cellulose synthase DUF948 PF06103.6 GAM21885.1 - 0.87 9.4 9.6 0.48 10.3 1.4 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PAT1 PF09770.4 GAM21885.1 - 1 7.5 53.3 1.6 6.8 36.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Reo_sigmaC PF04582.7 GAM21885.1 - 3.5 6.7 8.8 2.3 7.3 2.2 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Dapper PF15268.1 GAM21885.1 - 4.8 5.8 30.8 7.3 5.2 21.4 1.2 1 0 0 1 1 1 0 Dapper ATP11 PF06644.6 GAM21886.1 - 4.4e-54 183.7 1.6 4.4e-54 183.7 1.1 1.5 2 0 0 2 2 2 1 ATP11 protein YhhN PF07947.9 GAM21887.1 - 3.8e-32 111.1 19.1 5.7e-32 110.5 13.3 1.2 1 0 0 1 1 1 1 YhhN-like protein DUF4175 PF13779.1 GAM21887.1 - 0.76 7.4 2.6 1.1 6.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Amidase PF01425.16 GAM21888.1 - 5.7e-93 312.1 0.0 9.9e-93 311.3 0.0 1.3 1 0 0 1 1 1 1 Amidase GRAM PF02893.15 GAM21889.1 - 3.5e-10 39.2 0.0 8e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Ras PF00071.17 GAM21890.1 - 1.3e-58 197.0 0.3 1.5e-58 196.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21890.1 - 1.7e-15 57.5 0.0 2.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM21890.1 - 1.7e-11 43.6 0.0 2.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM21890.1 - 5.5e-05 22.4 0.0 7.9e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM21890.1 - 0.0084 15.5 0.0 0.024 14.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SieB PF14163.1 GAM21891.1 - 0.0079 15.7 0.1 0.0084 15.6 0.1 1.0 1 0 0 1 1 1 1 Superinfection exclusion protein B DUF2623 PF11115.3 GAM21891.1 - 0.087 12.7 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) Ribosomal_L37 PF08561.5 GAM21892.1 - 1.7e-07 30.7 0.2 2.7e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Proteasome PF00227.21 GAM21893.1 - 1.7e-54 184.0 0.4 2.3e-54 183.5 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM21893.1 - 1.4e-11 43.4 0.1 2.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PH_5 PF15405.1 GAM21893.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Rho_GDI PF02115.12 GAM21894.1 - 8.1e-58 195.1 0.0 9.1e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MBF1 PF08523.5 GAM21894.1 - 0.0036 17.2 0.2 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 Multiprotein bridging factor 1 DUF1934 PF09148.5 GAM21894.1 - 0.074 12.7 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1934) Endotoxin_C PF03944.9 GAM21894.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 delta endotoxin Ssu72 PF04722.8 GAM21895.1 - 7.1e-73 244.1 0.0 8.2e-73 243.9 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 GAM21895.1 - 0.0076 16.5 0.1 2.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Low molecular weight phosphotyrosine protein phosphatase DUF1754 PF08555.5 GAM21896.1 - 6e-09 36.4 19.1 1.2e-07 32.1 9.6 2.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Latrophilin PF02354.11 GAM21896.1 - 0.025 13.3 0.9 0.028 13.1 0.6 1.0 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region PP2C_C PF07830.8 GAM21896.1 - 0.026 14.6 0.6 0.099 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Anti-adapt_IraP PF10796.4 GAM21896.1 - 0.067 13.5 0.3 0.067 13.5 0.2 1.7 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Cep57_CLD PF14073.1 GAM21896.1 - 0.068 12.9 5.7 0.08 12.7 3.9 1.0 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Pap_E4 PF02711.9 GAM21896.1 - 0.24 12.2 3.9 0.36 11.6 2.7 1.2 1 0 0 1 1 1 0 E4 protein zf-RING_2 PF13639.1 GAM21897.1 - 2e-10 40.3 4.8 2e-10 40.3 3.3 3.7 3 1 0 3 3 3 1 Ring finger domain SPRY PF00622.23 GAM21897.1 - 9.2e-06 25.7 0.3 3.7e-05 23.8 0.2 2.1 1 1 0 1 1 1 1 SPRY domain zf-Di19 PF05605.7 GAM21897.1 - 2.9e-05 24.0 12.0 3.4e-05 23.8 5.6 3.0 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-rbx1 PF12678.2 GAM21897.1 - 0.00018 21.5 2.1 0.00018 21.5 1.4 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM21897.1 - 0.0018 18.2 5.7 0.0018 18.2 3.9 4.5 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM21897.1 - 0.89 9.2 17.5 0.26 10.9 2.9 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 GAM21897.1 - 2 8.2 7.9 5.2 6.9 2.0 2.9 1 1 2 3 3 3 0 Double zinc ribbon zf-RING_5 PF14634.1 GAM21897.1 - 4.4 7.1 15.9 1.5 8.6 3.2 3.5 3 0 0 3 3 3 0 zinc-RING finger domain Metallophos PF00149.23 GAM21898.1 - 3.8e-44 150.4 0.1 5e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TM2 PF05154.11 GAM21899.1 - 6.2e-19 67.9 12.9 8.5e-19 67.5 9.0 1.1 1 0 0 1 1 1 1 TM2 domain TrkH PF02386.11 GAM21900.1 - 5.7e-68 229.0 33.0 1.7e-66 224.2 17.4 2.5 2 1 0 2 2 2 2 Cation transport protein ABC2_membrane_3 PF12698.2 GAM21901.1 - 5.9e-18 65.0 38.5 5.9e-18 65.0 26.7 2.3 1 1 1 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.22 GAM21901.1 - 8.4e-14 52.0 0.0 1.8e-11 44.5 0.0 3.1 2 1 1 3 3 3 1 ABC transporter AAA_21 PF13304.1 GAM21901.1 - 2.1e-09 37.7 0.0 2.1e-09 37.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain ABC2_membrane_4 PF12730.2 GAM21901.1 - 0.0086 15.2 41.5 0.011 14.8 28.2 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF236 PF03057.9 GAM21901.1 - 0.3 11.0 3.6 4.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function Dict-STAT-coil PF09267.5 GAM21902.1 - 3.5e-34 117.4 12.9 3.5e-34 117.4 8.9 2.2 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 GAM21902.1 - 5.7e-08 32.4 0.0 1.9e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Condensin2nSMC PF12422.3 GAM21903.1 - 0.0034 17.1 2.2 0.11 12.2 0.0 3.2 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit Cnd1 PF12717.2 GAM21903.1 - 0.018 14.8 14.1 1.2 9.0 0.0 5.4 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF3439 PF11921.3 GAM21903.1 - 0.031 14.0 0.8 0.11 12.2 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Kelch_6 PF13964.1 GAM21904.1 - 3.9e-05 23.6 0.7 0.12 12.5 0.0 4.1 4 1 0 4 4 4 1 Kelch motif Kelch_4 PF13418.1 GAM21904.1 - 0.0033 17.1 0.6 1.1 9.0 0.0 3.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM21904.1 - 0.0057 16.7 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain HobA PF12163.3 GAM21904.1 - 0.0063 15.8 1.0 0.76 9.0 0.1 2.3 1 1 1 2 2 2 2 DNA replication regulator Kelch_1 PF01344.20 GAM21904.1 - 0.01 15.3 1.1 2.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Serine_rich PF08824.5 GAM21905.1 - 0.026 14.2 6.1 0.2 11.3 0.7 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain DUF3810 PF12725.2 GAM21905.1 - 0.049 12.5 1.1 0.18 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) STAT_alpha PF01017.15 GAM21905.1 - 0.24 11.1 6.5 0.8 9.3 4.2 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF1664 PF07889.7 GAM21905.1 - 1.6 8.5 8.6 0.67 9.7 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 GAM21905.1 - 2.8 8.3 5.8 1.4 9.2 0.4 2.5 2 1 1 3 3 3 0 Snapin/Pallidin Syntaxin-6_N PF09177.6 GAM21905.1 - 4.5 7.7 8.3 15 6.0 0.1 3.3 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Ras PF00071.17 GAM21906.1 - 1.9e-54 183.3 0.1 2.2e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM21906.1 - 8.9e-18 64.9 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM21906.1 - 4.8e-09 35.6 0.0 5.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM21906.1 - 6.6e-06 25.6 0.0 0.00011 21.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM21906.1 - 6.8e-05 22.7 0.0 0.0001 22.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM21906.1 - 0.00031 20.0 0.0 0.0015 17.7 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM21906.1 - 0.043 13.0 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM21906.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.19 GAM21907.1 - 3.9e-88 296.2 4.6 8.2e-88 295.1 3.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3109 PF11307.3 GAM21907.1 - 0.055 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) BPL_LplA_LipB PF03099.14 GAM21908.1 - 0.00077 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4549 PF15082.1 GAM21908.1 - 0.03 13.9 0.0 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) Drf_FH3 PF06367.11 GAM21909.1 - 7e-33 113.6 4.2 7e-33 113.6 2.9 2.0 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAM21909.1 - 1.3e-22 80.1 0.2 3e-22 78.8 0.2 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain FH2 PF02181.18 GAM21910.1 - 3.8e-84 282.7 8.2 5.2e-84 282.2 5.7 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Mucin PF01456.12 GAM21910.1 - 2.6 7.8 17.8 4.9 6.9 12.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_60s PF00428.14 GAM21910.1 - 4.8 7.6 7.1 20 5.6 1.3 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein UT PF03253.9 GAM21911.1 - 9.8e-45 152.7 27.6 1.1e-44 152.5 19.1 1.1 1 0 0 1 1 1 1 Urea transporter Exo_endo_phos PF03372.18 GAM21912.1 - 5e-18 65.9 0.1 7.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MaoC_dehydrat_N PF13452.1 GAM21912.1 - 0.0049 16.6 0.2 0.014 15.2 0.1 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase TILa PF12714.2 GAM21913.1 - 1.2 8.9 27.7 0.22 11.3 1.2 4.1 2 2 2 4 4 4 0 TILa domain Ammonium_transp PF00909.16 GAM21914.1 - 1.7e-37 128.8 22.9 7.9e-37 126.6 15.9 2.2 1 1 0 1 1 1 1 Ammonium Transporter Family ATG27 PF09451.5 GAM21915.1 - 1.9e-12 46.9 4.2 7.9e-11 41.6 2.9 2.4 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 GAM21915.1 - 2.9e-08 33.0 0.0 3.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 GAM21915.1 - 2.7e-05 23.9 1.2 2.7e-05 23.9 0.9 1.6 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat RCR PF12273.3 GAM21915.1 - 0.052 14.1 0.1 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red RasGEF PF00617.14 GAM21916.1 - 5e-56 189.4 0.9 9.8e-56 188.4 0.6 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM21916.1 - 6.9e-15 55.0 0.7 3.5e-14 52.7 0.5 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif DEP PF00610.16 GAM21916.1 - 3.3e-13 49.1 0.4 8.6e-13 47.8 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) WD40 PF00400.27 GAM21918.1 - 2.4e-17 62.0 21.1 0.0019 18.0 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat C1_1 PF00130.17 GAM21918.1 - 0.0043 16.7 7.2 0.01 15.5 5.0 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 GAM21918.1 - 0.0069 16.0 1.9 0.02 14.5 1.3 1.8 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RNHCP PF12647.2 GAM21918.1 - 0.02 14.6 5.8 0.052 13.3 4.0 1.7 1 0 0 1 1 1 0 RNHCP domain Prok-RING_1 PF14446.1 GAM21918.1 - 0.051 13.3 6.9 0.1 12.3 4.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PQQ_3 PF13570.1 GAM21918.1 - 0.1 12.8 0.0 0.93 9.8 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain PHD PF00628.24 GAM21918.1 - 0.13 11.9 5.5 0.29 10.8 3.8 1.6 1 0 0 1 1 1 0 PHD-finger DUF2652 PF10851.3 GAM21918.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2652) C1_4 PF07975.7 GAM21918.1 - 0.41 10.6 5.9 1.1 9.2 4.1 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain ABC2_membrane PF01061.19 GAM21919.1 - 9.6e-69 230.7 66.8 5.8e-36 123.6 16.7 3.0 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAM21919.1 - 1.1e-47 161.8 0.0 2.6e-24 86.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM21919.1 - 4.7e-11 43.1 7.5 0.00034 20.6 0.2 5.1 3 2 0 4 4 4 2 AAA domain AAA_25 PF13481.1 GAM21919.1 - 9.7e-08 31.6 0.1 0.023 14.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 GAM21919.1 - 1.9e-07 30.4 0.0 0.0026 16.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM21919.1 - 1.8e-06 28.0 0.0 0.053 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 GAM21919.1 - 2e-06 27.2 0.8 0.00079 18.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM21919.1 - 1.7e-05 24.9 0.0 0.23 11.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 GAM21919.1 - 6.3e-05 22.8 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 GAM21919.1 - 8.2e-05 22.4 0.0 0.053 13.2 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 GAM21919.1 - 0.00011 21.9 0.4 0.043 13.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 GAM21919.1 - 0.00015 21.9 0.1 0.059 13.5 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAM21919.1 - 0.00075 18.3 0.0 1 7.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 GAM21919.1 - 0.0027 17.8 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 GAM21919.1 - 0.0027 17.4 0.2 3.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 GAM21919.1 - 0.0034 17.3 0.2 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAM21919.1 - 0.0072 15.7 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 GAM21919.1 - 0.0079 16.5 0.1 6.4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 GAM21919.1 - 0.0086 15.9 0.0 1.2 9.1 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PDR_CDR PF06422.7 GAM21919.1 - 0.009 15.6 0.6 0.009 15.6 0.4 3.4 4 0 0 4 4 2 1 CDR ABC transporter MMR_HSR1 PF01926.18 GAM21919.1 - 0.01 15.7 0.1 6.5 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 GAM21919.1 - 0.014 14.8 1.0 3.9 6.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 GAM21919.1 - 0.019 14.1 0.1 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Miro PF08477.8 GAM21919.1 - 0.022 15.2 0.0 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 GAM21919.1 - 0.024 14.1 0.7 7 6.1 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 GAM21919.1 - 0.025 14.9 6.5 1 9.6 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 GAM21919.1 - 0.034 14.9 0.0 1.6 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM21919.1 - 0.034 13.7 0.8 3.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 GAM21919.1 - 0.038 13.8 0.1 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM21919.1 - 0.05 13.0 1.7 5.7 6.2 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 GAM21919.1 - 0.052 13.1 1.2 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAM21919.1 - 0.06 12.9 0.2 8.7 5.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 GAM21919.1 - 0.17 10.6 0.1 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 GAM21919.1 - 0.19 11.1 0.3 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.1 GAM21919.1 - 0.21 11.1 0.0 0.5 9.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM21919.1 - 0.28 10.9 2.5 5.6 6.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 GAM21919.1 - 0.31 9.8 0.7 6.7 5.4 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain PDR_assoc PF08370.6 GAM21919.1 - 4.2 6.9 13.2 2.5 7.6 0.7 3.1 3 0 0 3 3 2 0 Plant PDR ABC transporter associated TCR PF03638.10 GAM21920.1 - 1.3e-25 88.9 54.8 2.2e-13 49.8 16.5 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain CD34_antigen PF06365.7 GAM21921.1 - 0.017 14.7 0.2 0.032 13.8 0.2 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family stn_TNFRSF12A PF12191.3 GAM21921.1 - 0.045 13.8 0.3 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF912 PF06024.7 GAM21921.1 - 0.052 13.6 0.3 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HEAT PF02985.17 GAM21922.1 - 2.2e-37 123.7 8.1 0.00016 21.4 0.0 9.7 11 1 1 12 12 12 7 HEAT repeat HEAT_2 PF13646.1 GAM21922.1 - 6.8e-23 80.7 0.0 0.00079 19.6 0.0 6.2 2 2 2 6 6 6 5 HEAT repeats Vac14_Fab1_bd PF12755.2 GAM21922.1 - 5.1e-13 49.2 1.8 0.012 15.9 0.0 6.2 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAM21922.1 - 2.7e-09 37.2 0.0 0.73 10.4 0.0 6.3 6 1 1 7 7 7 2 HEAT-like repeat Arm PF00514.18 GAM21922.1 - 8.9e-07 28.5 0.8 2.8 7.9 0.0 6.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 GAM21922.1 - 0.0002 20.7 1.4 0.029 13.7 0.0 3.3 3 1 0 4 4 4 1 CLASP N terminal TFCD_C PF12612.3 GAM21922.1 - 0.0011 18.3 0.1 0.027 13.8 0.0 2.8 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal DUF4042 PF13251.1 GAM21922.1 - 0.0029 17.0 0.7 10 5.5 0.0 4.3 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) SRF-TF PF00319.13 GAM21923.1 - 1.4e-23 81.8 0.1 2.4e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Herpes_capsid PF06112.6 GAM21923.1 - 0.17 11.9 16.4 0.16 12.0 6.0 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein MSP1_C PF07462.6 GAM21923.1 - 0.62 8.3 3.0 0.99 7.7 2.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DOT1 PF08123.8 GAM21924.1 - 0.0022 17.3 0.2 1.1 8.5 0.0 2.4 1 1 1 2 2 2 2 Histone methylation protein DOT1 UL2 PF08196.6 GAM21924.1 - 0.096 12.4 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 UL2 protein Tom22 PF04281.8 GAM21924.1 - 0.099 12.1 6.6 0.074 12.5 3.2 1.8 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF936 PF06075.7 GAM21924.1 - 0.18 10.7 2.7 0.23 10.3 1.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MscS_TM PF12794.2 GAM21924.1 - 0.33 9.5 2.0 0.48 8.9 1.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FAM176 PF14851.1 GAM21924.1 - 0.49 10.0 3.5 1.2 8.7 2.4 1.7 1 0 0 1 1 1 0 FAM176 family Nup54 PF13874.1 GAM21925.1 - 8.9e-31 106.4 2.4 8.9e-31 106.4 1.7 2.6 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 GAM21925.1 - 1.4e-06 28.5 83.8 0.00018 21.7 30.5 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region RAB3GAP2_N PF14655.1 GAM21925.1 - 1.1 8.2 13.0 0.17 10.8 4.9 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus COX7C PF02935.11 GAM21927.1 - 0.0011 18.7 0.2 0.0013 18.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc TPR_12 PF13424.1 GAM21928.1 - 1e-10 41.3 0.5 0.0011 18.8 0.2 4.0 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM21928.1 - 4.2e-06 26.2 6.2 0.00093 18.7 0.1 4.4 4 2 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 GAM21928.1 - 3.8e-05 23.2 4.3 0.0028 17.4 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21928.1 - 9.1e-05 22.7 0.1 0.75 10.6 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM21928.1 - 0.00093 18.7 0.0 0.00093 18.7 0.0 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Syntaxin-18_N PF10496.4 GAM21928.1 - 0.0091 15.8 0.1 0.025 14.4 0.1 1.7 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus TPR_16 PF13432.1 GAM21928.1 - 0.035 14.7 0.1 6 7.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2400 PF09674.5 GAM21928.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Apc3 PF12895.2 GAM21928.1 - 0.064 13.3 0.6 2.2 8.4 0.0 3.1 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 GAM21928.1 - 0.93 9.4 6.3 10 6.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21928.1 - 1.2 9.5 4.2 38 4.7 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.14 GAM21929.1 - 2.1e-165 551.1 0.0 2.9e-165 550.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 GAM21929.1 - 8.9e-18 63.9 0.8 1.9e-17 62.8 0.5 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 GAM21929.1 - 0.042 13.5 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 DHHA1 domain Mod_r PF07200.8 GAM21929.1 - 0.3 10.9 4.1 0.45 10.4 0.9 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nucleoporin_FG PF13634.1 GAM21930.1 - 3.1e-13 49.9 96.3 6.3e-08 32.8 19.3 8.8 4 2 3 8 8 8 5 Nucleoporin FG repeat region zf-RanBP PF00641.13 GAM21930.1 - 0.068 12.2 6.3 0.13 11.4 4.4 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Band_7 PF01145.20 GAM21931.1 - 1.6e-06 28.1 2.2 1.6e-06 28.1 1.5 2.1 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 GAM21931.1 - 0.0043 16.6 0.1 0.0089 15.5 0.1 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Med12-PQL PF12144.3 GAM21931.1 - 0.16 11.3 0.2 0.38 10.1 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain Ank_2 PF12796.2 GAM21932.1 - 0.001 19.3 0.1 0.12 12.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) COMPASS-Shg1 PF05205.7 GAM21933.1 - 0.087 13.1 0.5 0.096 12.9 0.3 1.1 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 TOBE_3 PF12857.2 GAM21934.1 - 0.074 12.9 0.0 2.6 7.9 0.0 2.3 1 1 0 1 1 1 0 TOBE-like domain COMPASS-Shg1 PF05205.7 GAM21936.1 - 0.19 12.0 1.5 0.58 10.4 0.3 2.0 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SSrecog PF03531.9 GAM21937.1 - 6.2e-69 231.7 1.8 9.9e-69 231.0 1.3 1.3 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 GAM21937.1 - 1.9e-28 98.3 0.1 6.2e-26 90.2 0.1 2.5 2 0 0 2 2 2 2 Histone chaperone Rttp106-like Med10 PF09748.4 GAM21938.1 - 5.5e-28 97.3 4.9 7.6e-28 96.8 3.4 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3591 PF12157.3 GAM21938.1 - 0.0053 15.2 0.2 0.0068 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) DUF3972 PF13118.1 GAM21938.1 - 0.06 13.4 2.6 0.088 12.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) ABC_tran_2 PF12848.2 GAM21938.1 - 0.1 12.4 6.7 0.68 9.8 0.2 2.5 2 0 0 2 2 2 0 ABC transporter PAC2 PF09754.4 GAM21939.1 - 7e-23 81.6 0.0 2.9e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 PAC2 family Cbl_N PF02262.11 GAM21939.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 DUF2244 PF10003.4 GAM21940.1 - 0.53 9.6 2.5 0.66 9.3 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Pterin_4a PF01329.14 GAM21941.1 - 1.3e-32 111.3 0.1 1.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Yip1 PF04893.12 GAM21942.1 - 6.2e-14 51.8 19.2 9.2e-14 51.2 13.3 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 GAM21942.1 - 2.9 7.5 14.7 5.1 6.7 10.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Cpn60_TCP1 PF00118.19 GAM21943.1 - 1.3e-38 132.8 10.0 8.2e-38 130.2 7.0 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DnaB PF00772.16 GAM21943.1 - 0.063 13.1 1.4 2.8 7.8 0.0 3.1 3 0 0 3 3 3 0 DnaB-like helicase N terminal domain MazG-like PF12643.2 GAM21944.1 - 0.0019 18.0 1.9 0.0028 17.5 1.3 1.4 1 1 0 1 1 1 1 MazG-like family Prp19_bind PF06991.6 GAM21944.1 - 0.058 12.6 5.5 0.069 12.4 3.8 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain TFIIF_alpha PF05793.7 GAM21944.1 - 0.19 10.0 6.1 0.24 9.7 4.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MRP-S31 PF15433.1 GAM21944.1 - 0.19 11.1 7.3 0.23 10.8 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Suf PF05843.9 GAM21944.1 - 0.7 9.5 5.2 0.79 9.4 3.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4642 PF15484.1 GAM21944.1 - 1.2 9.0 8.2 1.5 8.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF1624 PF07786.7 GAM21945.1 - 0.12 11.7 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Ctr PF04145.10 GAM21945.1 - 5.4 7.0 6.8 4.3 7.3 1.0 2.0 1 1 1 2 2 2 0 Ctr copper transporter family Mito_carr PF00153.22 GAM21946.1 - 8.5e-74 243.3 2.4 5.7e-26 90.0 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein CbiZ PF01955.13 GAM21946.1 - 0.012 15.3 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase Cbl_N3 PF02762.9 GAM21946.1 - 0.13 11.8 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Chromate_transp PF02417.10 GAM21946.1 - 0.32 10.5 2.8 3.5 7.1 0.1 3.2 3 1 2 5 5 5 0 Chromate transporter FYVE PF01363.16 GAM21947.1 - 3.3e-16 58.9 14.8 3.3e-16 58.9 10.2 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 GAM21947.1 - 4.6e-11 42.8 8.0 4.3e-10 39.7 5.6 2.4 1 1 0 1 1 1 1 PH domain PH_3 PF14593.1 GAM21947.1 - 2.6e-07 30.4 2.9 0.013 15.3 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 GAM21947.1 - 0.00089 19.4 16.1 0.00092 19.4 7.0 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM21947.1 - 0.085 12.9 3.7 0.15 12.1 0.0 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain DUF2967 PF11179.3 GAM21947.1 - 0.39 10.1 14.6 0.91 8.9 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) zf-RING_5 PF14634.1 GAM21947.1 - 0.43 10.3 17.4 0.97 9.2 12.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Med15 PF09606.5 GAM21947.1 - 0.59 8.2 38.4 0.76 7.8 26.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C3HC4_4 PF15227.1 GAM21947.1 - 4.5 7.2 14.7 60 3.6 0.1 3.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING XRN_N PF03159.13 GAM21948.1 - 4.9e-78 261.7 0.0 4.9e-78 261.7 0.0 2.2 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus zf-AN1 PF01428.11 GAM21949.1 - 2.6e-10 40.0 9.7 6.3e-10 38.7 6.7 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger UBX PF00789.15 GAM21949.1 - 1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Metallophos PF00149.23 GAM21950.1 - 8e-16 58.0 0.2 1.4e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM21950.1 - 4.7e-15 55.4 0.2 2.2e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 GAM21950.1 - 2.3e-05 24.2 0.0 5.5e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 GAM21950.1 - 0.0019 16.8 1.1 0.0019 16.8 0.8 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase WD40 PF00400.27 GAM21951.1 - 8e-37 123.8 19.3 4.2e-08 32.7 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 GAM21951.1 - 6.3e-07 29.3 1.0 0.12 12.1 0.0 4.3 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 GAM21951.1 - 0.04 13.4 0.0 0.97 8.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 GAM21951.1 - 0.055 13.1 3.9 1.7 8.3 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3439 PF11921.3 GAM21951.1 - 0.18 11.5 11.1 0.43 10.3 7.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Proteasome_A_N PF10584.4 GAM21951.1 - 0.2 11.0 4.5 68 2.9 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Atrophin-1 PF03154.10 GAM21951.1 - 4.8 5.1 15.8 6.8 4.6 10.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family DNA_pol_E_B PF04042.11 GAM21952.1 - 2.3e-28 98.8 1.9 4.8e-28 97.8 1.3 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ketoacyl-synt PF00109.21 GAM21953.1 - 2.3e-52 178.0 0.1 2.3e-52 178.0 0.1 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM21953.1 - 2.1e-32 111.4 1.7 4.2e-32 110.4 1.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 GAM21953.1 - 0.00024 20.1 0.0 0.00059 18.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain FA_hydroxylase PF04116.8 GAM21954.1 - 1.4e-16 60.8 17.4 1.4e-16 60.8 12.1 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DIOX_N PF14226.1 GAM21955.1 - 1.5e-26 93.2 0.0 2.8e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM21955.1 - 8.9e-23 80.4 0.1 2.5e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EB PF01683.13 GAM21956.1 - 0.21 11.6 2.2 0.8 9.8 1.7 1.9 1 1 1 2 2 2 0 EB module DENN PF02141.16 GAM21957.1 - 3.1e-30 105.2 0.9 9.1e-30 103.7 0.6 1.9 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAM21957.1 - 1.7e-08 34.3 0.4 1.8e-07 31.0 0.3 2.7 1 1 0 1 1 1 1 uDENN domain DUF4559 PF15112.1 GAM21957.1 - 0.059 12.5 4.5 0.1 11.7 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) RGS PF00615.14 GAM21958.1 - 1.4e-24 86.4 1.7 1.8e-24 86.1 1.2 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain YTV PF07639.6 GAM21959.1 - 0.0043 16.7 1.0 0.007 16.0 0.1 1.8 2 0 0 2 2 2 1 YTV FAM92 PF06730.6 GAM21959.1 - 0.0088 15.3 0.3 0.012 14.9 0.2 1.2 1 0 0 1 1 1 1 FAM92 protein TIG PF01833.19 GAM21960.1 - 0.0013 18.6 8.8 0.014 15.3 0.3 2.9 3 0 0 3 3 3 2 IPT/TIG domain DUF3481 PF11980.3 GAM21960.1 - 0.015 15.1 0.0 0.054 13.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) ATP-synt_8 PF00895.15 GAM21960.1 - 0.078 13.1 2.7 1.7 8.8 0.1 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 Shisa PF13908.1 GAM21960.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SNARE PF05739.14 GAM21962.1 - 2.9e-14 52.4 0.9 3.4e-14 52.2 0.6 1.1 1 0 0 1 1 1 1 SNARE domain DUF768 PF05589.6 GAM21962.1 - 0.073 13.0 0.1 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF768) Phage_Gp23 PF10669.4 GAM21963.1 - 0.061 13.4 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) M_domain PF12938.2 GAM21963.1 - 0.18 11.6 5.2 0.2 11.4 3.6 1.0 1 0 0 1 1 1 0 M domain of GW182 DUF4419 PF14388.1 GAM21964.1 - 1.9e-96 322.8 0.7 2.3e-96 322.5 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) IPPT PF01715.12 GAM21965.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 IPP transferase Ank_2 PF12796.2 GAM21966.1 - 5.4e-38 129.2 9.5 3.5e-09 36.8 0.0 6.4 5 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM21966.1 - 6.9e-28 95.0 20.1 3.1e-07 29.8 0.4 10.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.1 GAM21966.1 - 7.1e-27 92.8 13.1 5.1e-09 36.0 0.0 7.7 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM21966.1 - 2.2e-26 91.7 15.4 3.6e-06 27.3 0.1 8.2 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM21966.1 - 1.5e-19 68.0 15.6 0.0015 18.5 0.1 10.1 10 0 0 10 10 10 5 Ankyrin repeat FNIP PF05725.7 GAM21967.1 - 4.1e-75 247.4 23.4 1.7e-14 53.4 0.0 9.9 6 4 2 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 GAM21967.1 - 0.00054 19.8 0.9 4.1 7.4 0.0 4.4 2 2 2 4 4 4 2 Protein of unknown function (DUF1769) LRR_7 PF13504.1 GAM21967.1 - 0.22 11.8 4.4 1.9e+02 2.9 0.0 6.2 6 0 0 6 6 6 0 Leucine rich repeat FNIP PF05725.7 GAM21968.1 - 8.1e-29 99.3 28.8 1.5e-05 24.8 0.0 9.3 7 3 2 9 9 9 8 FNIP Repeat DUF4419 PF14388.1 GAM21970.1 - 8.2e-108 360.1 2.0 9.6e-108 359.9 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) TPR_11 PF13414.1 GAM21971.1 - 2.2e-23 81.6 2.8 4.7e-14 51.7 1.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM21971.1 - 1.5e-12 46.5 2.7 6.2e-05 22.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21971.1 - 1.1e-10 40.5 3.7 0.008 16.0 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21971.1 - 1.4e-05 24.9 4.9 0.0017 18.2 1.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21971.1 - 2.2e-05 24.2 0.7 6.6 7.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21971.1 - 0.00069 20.0 0.2 0.0052 17.3 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21971.1 - 0.0051 16.5 6.1 0.065 13.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21971.1 - 0.0082 16.4 0.2 0.024 14.9 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat SART-1 PF03343.8 GAM21972.1 - 0.074 11.3 17.7 0.08 11.2 12.3 1.1 1 0 0 1 1 1 0 SART-1 family TAF1D PF15333.1 GAM21972.1 - 0.65 9.7 11.6 0.74 9.5 8.0 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Vfa1 PF08432.5 GAM21972.1 - 0.94 9.4 16.3 1.2 9.1 11.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3464 PF11947.3 GAM21972.1 - 2 7.8 4.8 2.8 7.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Corona_nucleoca PF00937.13 GAM21972.1 - 8.3 5.2 11.4 13 4.6 7.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Rep_fac-A_C PF08646.5 GAM21973.1 - 0.00018 21.2 0.6 0.0003 20.5 0.4 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain DZR PF12773.2 GAM21973.1 - 0.054 13.3 1.5 0.13 12.0 1.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon DUF2838 PF10998.3 GAM21974.1 - 2.4e-33 114.3 11.1 2.4e-33 114.3 7.7 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) CAML PF14963.1 GAM21974.1 - 0.019 14.3 3.7 0.037 13.3 2.6 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Sigma70_ner PF04546.8 GAM21974.1 - 0.063 12.8 6.3 0.1 12.1 4.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Enkurin PF13864.1 GAM21974.1 - 0.18 12.0 5.7 0.53 10.5 3.8 1.9 1 1 0 1 1 1 0 Calmodulin-binding NOA36 PF06524.7 GAM21974.1 - 1.9 7.6 4.8 3.7 6.7 3.4 1.5 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 GAM21975.1 - 2.5e-49 163.4 16.9 6.2e-12 44.9 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM21975.1 - 7.9e-08 32.2 1.4 0.00012 21.8 0.2 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 GAM21975.1 - 0.00052 19.7 0.2 0.00097 18.8 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SGL PF08450.7 GAM21975.1 - 0.0019 17.6 0.3 0.17 11.2 0.1 2.9 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Acetyltransf_4 PF13420.1 GAM21977.1 - 9.6e-22 77.5 0.0 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM21977.1 - 3.3e-11 43.0 0.0 5.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM21977.1 - 1.6e-08 34.6 0.0 2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM21977.1 - 5e-08 33.2 0.0 6e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM21977.1 - 2.9e-05 23.7 0.0 6.3e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 GAM21977.1 - 0.038 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM21977.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hist_deacetyl PF00850.14 GAM21978.1 - 1.2e-77 261.2 1.5 3e-77 259.9 0.2 1.8 2 0 0 2 2 2 1 Histone deacetylase domain NIF PF03031.13 GAM21980.1 - 2.2e-28 98.9 3.3 5.2e-27 94.4 0.8 2.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 GAM21980.1 - 4e-11 42.5 0.1 8.6e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 GAM21980.1 - 4.5e-10 39.5 0.0 2e-09 37.4 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Popeye PF04831.8 GAM21980.1 - 0.0078 15.9 0.2 0.018 14.8 0.1 1.6 1 0 0 1 1 1 1 Popeye protein conserved region Biotin_lipoyl_2 PF13533.1 GAM21980.1 - 0.079 12.6 0.0 9.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like SOG2 PF10428.4 GAM21980.1 - 2 7.0 19.2 3.9 6.0 13.3 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Tubulin PF00091.20 GAM21981.1 - 3.7e-69 232.8 0.0 5.5e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM21981.1 - 7.9e-50 168.1 1.0 1.3e-49 167.3 0.1 1.8 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAM21981.1 - 2.5e-07 30.7 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain CN_hydrolase PF00795.17 GAM21981.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase Tubulin_2 PF13809.1 GAM21981.1 - 0.046 12.6 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DNA_primase_lrg PF04104.9 GAM21982.1 - 4e-61 206.5 0.1 6.1e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Isochorismatase PF00857.15 GAM21983.1 - 7.1e-33 113.9 0.0 8.9e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Ank_2 PF12796.2 GAM21984.1 - 1.4e-20 73.4 3.4 3.8e-18 65.6 0.2 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM21984.1 - 1.7e-14 53.8 2.5 3.3e-08 33.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM21984.1 - 7.5e-14 51.4 0.6 3.7e-07 30.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM21984.1 - 3.1e-13 48.7 1.0 8.4e-06 25.3 0.3 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 GAM21984.1 - 2.9e-10 39.3 0.3 0.0077 16.3 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat PAP_central PF04928.12 GAM21985.1 - 1.7e-98 328.4 0.0 3.9e-98 327.2 0.0 1.6 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 GAM21985.1 - 1.2e-40 138.5 0.0 2.2e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 GAM21985.1 - 1.7e-09 37.9 0.0 4.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF605 PF04652.11 GAM21985.1 - 0.1 11.9 22.5 0.14 11.4 15.6 1.2 1 0 0 1 1 1 0 Vta1 like MOFRL PF05161.8 GAM21986.1 - 0.054 13.6 0.0 0.06 13.4 0.0 1.0 1 0 0 1 1 1 0 MOFRL family Homeobox_KN PF05920.6 GAM21987.1 - 5.9e-16 57.8 0.7 1.3e-15 56.8 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAM21987.1 - 9e-07 28.4 0.1 1.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Sec2p PF06428.6 GAM21987.1 - 0.1 12.4 0.6 0.25 11.1 0.4 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p YL1 PF05764.8 GAM21987.1 - 0.15 11.6 2.2 2.2 7.8 0.3 2.5 2 1 0 2 2 2 0 YL1 nuclear protein DUF3605 PF12239.3 GAM21988.1 - 1.3e-19 70.5 6.7 1.7e-18 66.9 4.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) FNIP PF05725.7 GAM21989.1 - 4e-37 125.9 7.8 4.4e-09 36.1 0.1 9.1 5 2 4 9 9 9 7 FNIP Repeat LCM PF04072.9 GAM21990.1 - 6.3e-25 87.8 0.0 9.8e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Nse4_C PF08743.5 GAM21991.1 - 2.4e-22 78.7 0.1 7.1e-22 77.2 0.1 1.9 1 0 0 1 1 1 1 Nse4 C-terminal E1_DerP2_DerF2 PF02221.10 GAM21991.1 - 1.1e-20 74.2 0.4 1.7e-20 73.5 0.3 1.4 1 0 0 1 1 1 1 ML domain Nse4-Nse3_bdg PF15412.1 GAM21991.1 - 7.6e-09 35.2 0.2 1.6e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE TRP_N PF14558.1 GAM21991.1 - 0.0018 18.3 0.7 0.0063 16.5 0.5 1.9 1 1 0 1 1 1 1 ML-like domain DUF3752 PF12572.3 GAM21991.1 - 0.085 12.9 3.3 0.043 13.9 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DUF4539 PF15072.1 GAM21992.1 - 4.6e-24 83.9 0.0 8.8e-24 83.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) AIG1 PF04548.11 GAM21993.1 - 4.2e-10 39.0 1.7 3.3e-09 36.1 1.2 2.4 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAM21993.1 - 4.6e-10 39.4 1.4 1e-09 38.3 0.2 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase zf-trcl PF13451.1 GAM21993.1 - 1.3e-05 24.6 13.5 0.00014 21.3 0.3 3.5 3 1 0 3 3 3 2 Probable zinc-binding domain Dynamin_N PF00350.18 GAM21993.1 - 6e-05 22.9 8.9 0.042 13.6 0.1 4.0 4 0 0 4 4 4 2 Dynamin family FtsK_SpoIIIE PF01580.13 GAM21993.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF258 PF03193.11 GAM21993.1 - 0.00037 19.7 0.2 0.00037 19.7 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM21993.1 - 0.0013 19.0 16.0 0.76 10.0 11.1 2.9 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 GAM21993.1 - 0.0015 17.5 0.0 0.0045 16.0 0.0 1.8 1 0 0 1 1 1 1 Septin AAA_29 PF13555.1 GAM21993.1 - 0.0018 17.7 0.1 0.0043 16.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM21993.1 - 0.0023 18.2 0.4 0.016 15.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter MobB PF03205.9 GAM21993.1 - 0.0034 17.0 0.5 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAM21993.1 - 0.0035 17.4 0.0 0.013 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM21993.1 - 0.0044 15.9 0.1 0.013 14.3 0.1 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 GAM21993.1 - 0.0063 16.5 0.1 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 GAM21993.1 - 0.0082 15.2 0.6 3.5 6.6 0.0 2.5 2 0 0 2 2 2 2 KaiC Ras PF00071.17 GAM21993.1 - 0.0093 15.3 0.1 0.028 13.8 0.0 1.9 1 0 0 1 1 1 1 Ras family RNA_helicase PF00910.17 GAM21993.1 - 0.012 15.7 0.5 0.075 13.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 GAM21993.1 - 0.013 14.9 1.8 0.016 14.6 0.1 1.9 3 0 0 3 3 3 0 AAA-like domain GTP_EFTU PF00009.22 GAM21993.1 - 0.017 14.5 0.3 0.058 12.8 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 GAM21993.1 - 0.017 14.6 4.4 0.2 11.1 0.0 2.9 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 GAM21993.1 - 0.022 14.0 3.9 2.4 7.4 0.1 3.2 2 1 1 3 3 3 0 Ferrous iron transport protein B DUF87 PF01935.12 GAM21993.1 - 0.031 14.1 2.8 0.032 14.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 GAM21993.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 GAM21993.1 - 0.062 13.7 0.2 0.062 13.7 0.1 3.2 3 1 0 3 3 2 0 Miro-like protein AAA_17 PF13207.1 GAM21993.1 - 0.086 13.6 0.0 0.24 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 GAM21994.1 - 1.2e-33 114.6 32.0 1.7e-07 30.7 0.1 9.4 7 1 2 10 10 10 7 TPR repeat TPR_1 PF00515.23 GAM21994.1 - 1.1e-27 94.4 30.8 1.8e-05 24.1 0.0 13.1 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAM21994.1 - 1.2e-26 90.4 30.2 5e-05 22.9 0.0 12.6 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_16 PF13432.1 GAM21994.1 - 1.3e-17 63.9 6.6 0.0049 17.5 0.3 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM21994.1 - 6.3e-17 60.5 6.7 0.0059 17.1 0.0 9.7 8 2 3 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 GAM21994.1 - 2.3e-16 59.8 21.6 0.0007 19.8 0.8 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAM21994.1 - 1.3e-14 52.7 19.7 0.00047 19.7 0.0 10.8 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM21994.1 - 1.6e-14 53.5 29.9 0.0049 16.7 0.2 9.5 6 4 3 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM21994.1 - 6.8e-13 47.7 18.8 0.011 15.8 0.0 10.5 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM21994.1 - 3.2e-10 39.6 3.1 0.1 12.4 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM21994.1 - 1.1e-09 38.3 25.0 0.00074 19.6 0.1 6.9 5 3 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAM21994.1 - 6.5e-07 28.6 8.1 3.7 7.5 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM21994.1 - 0.0019 18.2 6.3 2.1 8.5 0.1 6.4 5 3 4 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM21994.1 - 0.097 13.1 16.3 7.1 7.3 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat ChAPs PF09295.5 GAM21994.1 - 0.29 9.8 6.3 0.41 9.3 0.3 2.9 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) GPCR_chapero_1 PF11904.3 GAM21995.1 - 9.8e-28 97.1 1.0 1.5e-27 96.6 0.7 1.2 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 GAM21995.1 - 8.1e-10 38.9 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM21995.1 - 7.7e-09 35.5 0.1 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM21995.1 - 4.3e-08 33.4 0.3 0.00018 21.8 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM21995.1 - 2.6e-06 26.9 0.0 3e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 GAM21995.1 - 0.0001 22.1 0.0 0.00034 20.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat LRR_6 PF13516.1 GAM21996.1 - 2.7e-10 39.2 19.6 0.046 13.8 0.2 7.9 8 0 0 8 8 8 4 Leucine Rich repeat SAPS PF04499.10 GAM21996.1 - 4.2e-06 25.6 0.6 4.2e-06 25.6 0.4 4.1 3 1 0 3 3 3 2 SIT4 phosphatase-associated protein tRNA-synt_1c PF00749.16 GAM21997.1 - 2.4e-109 364.7 0.7 3.1e-109 364.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 GAM21997.1 - 1e-50 171.8 0.3 2.9e-50 170.3 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 GAM21997.1 - 2.5e-41 140.9 0.3 4.5e-41 140.1 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 GAM21997.1 - 1.1e-10 41.9 1.4 3.3e-10 40.5 0.9 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GBV-C_env PF12786.2 GAM21997.1 - 0.022 13.2 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope tRNA-synt_1e PF01406.14 GAM21997.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF393 PF04134.7 GAM21999.1 - 5.3e-22 79.0 0.0 7e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Pkinase_Tyr PF07714.12 GAM22000.1 - 3.1e-49 167.4 0.0 4.7e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM22000.1 - 6.1e-48 163.2 0.0 1.2e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAM22000.1 - 6.5e-32 109.7 1.7 3.5e-12 46.4 0.2 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM22000.1 - 3.2e-27 92.9 1.7 6.3e-06 25.7 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAM22000.1 - 2.6e-25 88.3 2.3 1.1e-06 28.9 0.2 5.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22000.1 - 8.9e-21 71.9 2.0 0.00027 20.9 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAM22000.1 - 7.4e-17 61.0 15.6 4.3e-07 29.9 0.0 5.0 5 1 1 6 6 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.25 GAM22000.1 - 1.5e-14 53.8 0.5 6.5e-14 51.8 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM22000.1 - 9.2e-10 38.2 0.2 2.2e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2407 PF10302.4 GAM22000.1 - 0.036 14.2 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain APH PF01636.18 GAM22000.1 - 0.039 13.6 0.6 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 GAM22000.1 - 0.047 13.0 0.3 0.25 10.6 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Endonuc-MspI PF09208.5 GAM22001.1 - 0.084 11.9 1.0 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease MspI Pkinase_Tyr PF07714.12 GAM22002.1 - 3.8e-61 206.4 0.0 5.5e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM22002.1 - 7.2e-47 159.7 0.0 1.2e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 GAM22002.1 - 2e-37 126.2 46.3 1.9e-08 33.7 1.0 7.5 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM22002.1 - 1.1e-33 114.7 41.2 2.8e-11 43.0 4.5 6.3 2 2 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 GAM22002.1 - 1.3e-21 73.2 48.6 0.025 14.5 0.2 13.1 12 0 0 12 12 12 8 Leucine Rich Repeat LRR_7 PF13504.1 GAM22002.1 - 1.5e-16 57.5 38.7 0.28 11.5 0.1 12.8 12 0 0 12 12 12 8 Leucine rich repeat LRR_9 PF14580.1 GAM22002.1 - 3.3e-06 26.7 11.0 0.12 11.9 0.6 4.0 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.1 GAM22002.1 - 6.4e-05 22.6 44.8 1.6 9.0 0.2 11.8 8 2 4 12 12 12 3 Leucine Rich repeat APH PF01636.18 GAM22002.1 - 0.0076 16.0 0.6 20 4.7 0.1 3.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family LRR_3 PF07725.7 GAM22002.1 - 9.9 6.1 8.3 63 3.6 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat DUF2404 PF10296.4 GAM22003.1 - 4.8e-25 87.5 0.3 1.1e-24 86.4 0.2 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 GAM22003.1 - 7.8e-07 29.2 0.6 2.4e-06 27.6 0.4 1.9 1 0 0 1 1 1 1 PH domain E1-E2_ATPase PF00122.15 GAM22004.1 - 5.3e-30 104.1 0.7 5.3e-30 104.1 0.5 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM22004.1 - 1e-29 103.3 13.3 1e-29 103.3 9.2 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM22004.1 - 2.1e-11 44.6 0.1 3.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM22004.1 - 3.8e-06 27.2 0.1 1e-05 25.8 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM22004.1 - 0.014 15.3 0.0 0.14 12.1 0.0 2.4 1 1 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Phos_pyr_kin PF08543.7 GAM22005.1 - 4.3e-18 65.4 0.0 5.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 GAM22005.1 - 4.6e-14 52.2 0.4 1.3e-13 50.7 0.3 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF3029 PF11230.3 GAM22005.1 - 0.0012 17.1 0.0 0.0018 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3029) HAD PF12710.2 GAM22005.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PIP5K PF01504.13 GAM22006.1 - 1.7e-81 273.0 0.0 2.5e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase RhoGAP PF00620.22 GAM22007.1 - 1.1e-21 77.0 0.3 3.6e-21 75.3 0.2 1.9 1 0 0 1 1 1 1 RhoGAP domain RCC1 PF00415.13 GAM22009.1 - 9.4e-32 108.9 9.0 9.3e-08 32.1 0.0 7.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM22009.1 - 1.5e-19 69.0 19.7 7.3e-05 22.2 0.0 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Aminotran_1_2 PF00155.16 GAM22010.1 - 3.2e-46 157.9 0.0 3.7e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II STAG PF08514.6 GAM22012.1 - 3.2e-13 49.4 0.2 3.2e-13 49.4 0.1 3.0 3 0 0 3 3 3 1 STAG domain DUF2201_N PF13203.1 GAM22012.1 - 7.6 5.6 14.8 0.53 9.4 3.4 2.4 2 0 0 2 2 2 0 Putative metallopeptidase domain HlyIII PF03006.15 GAM22013.1 - 0.39 10.1 15.2 0.18 11.1 8.9 1.6 1 1 1 2 2 2 0 Haemolysin-III related Peptidase_M50B PF13398.1 GAM22013.1 - 0.5 9.7 18.4 0.1 11.9 9.9 1.7 1 1 1 2 2 2 0 Peptidase M50B-like UPF0126 PF03458.8 GAM22013.1 - 0.58 9.8 12.7 0.11 12.1 5.7 2.1 1 1 1 2 2 2 0 UPF0126 domain CbiQ PF02361.11 GAM22013.1 - 1.3 8.5 11.1 1.7 8.1 7.7 1.3 1 0 0 1 1 1 0 Cobalt transport protein Tetraspannin PF00335.15 GAM22013.1 - 3.2 6.9 30.2 0.096 11.9 12.0 2.5 1 1 1 2 2 2 0 Tetraspanin family RCC1 PF00415.13 GAM22014.1 - 1.7e-61 204.2 24.0 2.3e-14 53.3 0.7 8.3 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM22014.1 - 7.3e-46 152.8 32.2 1.5e-08 33.9 0.6 7.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 GAM22014.1 - 0.0024 17.3 2.8 6.6 6.3 0.3 4.0 4 0 0 4 4 4 2 Putative carbohydrate binding domain Kelch_2 PF07646.10 GAM22014.1 - 0.12 12.1 2.0 42 4.1 0.0 4.1 4 0 0 4 4 4 0 Kelch motif YoqO PF14037.1 GAM22015.1 - 2.3 8.3 9.4 2 8.5 5.3 1.7 1 1 1 2 2 2 0 YoqO-like protein DUF1700 PF08006.6 GAM22015.1 - 4.4 6.5 6.8 5 6.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4191 PF13829.1 GAM22015.1 - 5.1 6.1 5.7 5.9 5.9 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FNIP PF05725.7 GAM22016.1 - 1.2e-52 175.5 8.1 1.8e-10 40.5 0.1 7.3 6 1 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM22016.1 - 0.065 13.1 0.4 2.9 7.8 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1769) Polysacc_deac_1 PF01522.16 GAM22016.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase TIG PF01833.19 GAM22017.1 - 1.3e-05 25.1 27.7 0.00052 19.9 0.8 5.7 6 0 0 6 6 6 3 IPT/TIG domain Lectin_C PF00059.16 GAM22017.1 - 0.025 15.2 0.0 0.068 13.8 0.0 1.8 1 0 0 1 1 1 0 Lectin C-type domain EGF_2 PF07974.8 GAM22017.1 - 3.4 7.8 13.0 6.8 6.9 9.0 1.5 1 0 0 1 1 1 0 EGF-like domain MutS_V PF00488.16 GAM22018.1 - 1.5e-97 325.6 0.0 2.4e-97 324.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM22018.1 - 3.5e-35 121.6 4.6 4.6e-35 121.2 1.0 2.3 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.13 GAM22018.1 - 1.6e-12 47.4 1.2 1.6e-12 47.4 0.8 2.5 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 GAM22018.1 - 2.6e-11 43.7 1.1 1.3e-10 41.4 0.0 2.6 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 GAM22018.1 - 7.4e-09 35.6 0.2 0.0038 17.2 0.1 2.7 2 0 0 2 2 2 2 MutS domain I SnoaL_2 PF12680.2 GAM22019.1 - 0.0018 18.6 0.1 0.0028 18.0 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 GAM22019.1 - 0.0024 17.4 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NAM PF02365.10 GAM22019.1 - 0.033 14.3 0.4 0.043 14.0 0.3 1.3 1 0 0 1 1 1 0 No apical meristem (NAM) protein CHIPS PF11434.3 GAM22019.1 - 0.096 12.3 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS SAM_decarbox PF01536.11 GAM22020.1 - 2.7e-104 348.4 0.0 3.3e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Herpes_U30 PF04523.8 GAM22020.1 - 0.13 9.6 0.0 0.19 9.1 0.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 7tm_3 PF00003.17 GAM22021.1 - 3.2e-19 69.2 9.7 5.3e-19 68.4 6.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 GAM22021.1 - 2.3e-11 43.0 1.7 3.4e-11 42.4 1.2 1.2 1 0 0 1 1 1 1 Basic membrane protein DUF998 PF06197.8 GAM22021.1 - 0.021 14.1 0.7 3.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF998) IncA PF04156.9 GAM22021.1 - 0.04 13.5 0.6 0.094 12.3 0.4 1.5 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 GAM22022.1 - 1.8e-45 151.2 11.0 3.9e-09 36.0 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat Sld5 PF05916.6 GAM22023.1 - 0.0001 22.5 0.1 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein ApbA_C PF08546.6 GAM22023.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal ECH PF00378.15 GAM22025.1 - 6.7e-55 185.8 0.1 7.8e-55 185.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAM22025.1 - 0.0026 17.5 0.2 1.1 9.0 0.0 2.5 3 0 0 3 3 3 2 Peptidase family S49 Mpv17_PMP22 PF04117.7 GAM22026.1 - 5.9e-23 80.2 1.6 1e-22 79.5 1.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family ArfGap PF01412.13 GAM22027.1 - 1.7e-37 127.8 0.2 1.7e-37 127.8 0.1 2.6 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 GAM22027.1 - 4.7e-15 55.6 7.2 2.1e-11 43.9 2.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.24 GAM22027.1 - 3e-14 53.0 0.4 3e-14 53.0 0.3 2.6 3 0 0 3 3 3 1 PH domain Ank_5 PF13857.1 GAM22027.1 - 7.8e-13 48.2 5.7 6e-10 39.0 0.5 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM22027.1 - 4.7e-12 45.0 6.2 0.00081 19.0 0.4 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAM22027.1 - 1.3e-10 41.5 1.0 2.6e-06 27.7 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22027.1 - 2.1e-07 30.4 1.8 0.075 13.3 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeat BAR PF03114.13 GAM22027.1 - 3.2e-07 30.0 9.0 7.3e-07 28.9 6.2 1.5 1 0 0 1 1 1 1 BAR domain PH_11 PF15413.1 GAM22027.1 - 5.3e-07 29.8 1.2 8.7e-06 25.9 0.4 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain Syntaxin_2 PF14523.1 GAM22027.1 - 2.3e-05 24.3 0.2 2.3e-05 24.3 0.1 3.2 3 1 0 3 3 3 1 Syntaxin-like protein PH_8 PF15409.1 GAM22027.1 - 7.4e-05 22.7 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PLC-beta_C PF08703.5 GAM22027.1 - 0.41 10.3 10.2 0.12 12.1 1.7 2.7 3 0 0 3 3 3 0 PLC-beta C terminal Nop14 PF04147.7 GAM22028.1 - 0.17 9.7 4.8 0.22 9.4 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Kelch_6 PF13964.1 GAM22029.1 - 5.3e-08 32.7 6.5 0.015 15.4 0.1 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 GAM22029.1 - 0.068 12.9 0.8 1.7 8.5 0.1 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 GAM22030.1 - 2.7e-07 30.4 2.9 0.021 15.0 0.1 4.8 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM22030.1 - 0.00063 19.4 6.8 0.72 9.6 0.0 5.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Snapin_Pallidin PF14712.1 GAM22030.1 - 0.076 13.3 6.3 0.1 12.9 2.3 2.2 2 0 0 2 2 2 0 Snapin/Pallidin DUF3688 PF12461.3 GAM22030.1 - 0.08 13.3 0.3 0.08 13.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3688) Baculo_PEP_C PF04513.7 GAM22030.1 - 0.16 11.7 10.8 0.052 13.3 5.4 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM22030.1 - 0.26 11.0 5.0 0.37 10.6 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 GAM22030.1 - 0.41 10.1 7.3 0.14 11.7 2.8 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sec20 PF03908.8 GAM22030.1 - 1.9 8.2 9.7 0.61 9.8 2.9 2.8 3 0 0 3 3 3 0 Sec20 FNIP PF05725.7 GAM22031.1 - 1.2e-106 348.3 32.0 7.7e-16 57.7 0.0 10.1 3 2 8 13 13 13 12 FNIP Repeat LRR_7 PF13504.1 GAM22031.1 - 4.1 8.0 8.4 25 5.6 0.0 6.0 7 1 0 7 7 7 0 Leucine rich repeat MBOAT PF03062.14 GAM22032.1 - 1.7e-45 155.5 14.8 1.7e-45 155.5 10.2 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family LRR_6 PF13516.1 GAM22033.1 - 4.8e-07 29.1 1.1 4.2 7.7 0.0 7.3 6 1 1 7 7 7 2 Leucine Rich repeat Mito_fiss_reg PF05308.6 GAM22034.1 - 4.7 6.4 6.7 5.5 6.2 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.17 GAM22035.1 - 1.2e-16 60.0 0.0 1.2e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22035.1 - 3.2e-14 52.5 0.0 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22035.1 - 6e-14 51.7 0.1 1.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.17 GAM22035.1 - 2.1e-12 46.5 0.0 4.8e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain Limkain-b1 PF11608.3 GAM22035.1 - 0.0015 18.2 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 Cupin_4 PF08007.7 GAM22035.1 - 0.057 12.6 0.0 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein Mito_fiss_reg PF05308.6 GAM22035.1 - 0.058 12.7 4.4 0.16 11.3 3.0 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator Nup35_RRM_2 PF14605.1 GAM22035.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Beach PF02138.13 GAM22037.1 - 9.2e-110 366.3 3.5 1.5e-109 365.6 2.4 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM22037.1 - 8.9e-20 70.5 0.1 2.8e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 GAM22037.1 - 5e-12 46.3 0.1 3e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 GAM22037.1 - 2.4e-08 33.5 7.6 0.00012 21.8 0.3 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat GRAM PF02893.15 GAM22037.1 - 0.022 14.2 0.0 0.065 12.7 0.0 1.7 1 0 0 1 1 1 0 GRAM domain CD36 PF01130.16 GAM22039.1 - 8e-55 185.9 6.1 2e-30 105.5 0.1 2.4 2 1 0 2 2 2 2 CD36 family Sugar_tr PF00083.19 GAM22040.1 - 3.3e-69 233.6 37.6 8.5e-40 136.6 13.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 GAM22040.1 - 3e-22 78.8 37.3 1.1e-15 57.2 8.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 GAM22040.1 - 0.0017 16.9 4.9 0.0017 16.9 3.4 3.5 3 1 0 3 3 3 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 GAM22040.1 - 0.063 11.3 16.3 0.08 11.0 3.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Lig_chan PF00060.21 GAM22040.1 - 3.3 7.4 6.2 16 5.1 2.5 2.9 1 1 0 1 1 1 0 Ligand-gated ion channel DUF543 PF04418.7 GAM22040.1 - 9.9 6.1 7.7 2.9 7.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF543) ubiquitin PF00240.18 GAM22041.1 - 2.6e-21 74.7 0.3 4.9e-21 73.8 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM22041.1 - 6.3e-12 45.0 0.2 1.1e-11 44.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 GAM22041.1 - 5.4e-10 38.7 2.0 7.5e-10 38.3 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 GAM22041.1 - 1.8e-05 24.8 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 GAM22041.1 - 8.1e-05 22.8 0.4 0.00021 21.4 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Pik1 PF11522.3 GAM22041.1 - 0.0035 17.0 0.1 0.017 14.8 0.1 2.2 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 CUE PF02845.11 GAM22041.1 - 0.017 14.6 0.5 0.017 14.6 0.3 2.3 2 0 0 2 2 2 0 CUE domain Rad60-SLD_2 PF13881.1 GAM22041.1 - 0.029 14.2 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PUB PF09409.5 GAM22041.1 - 0.035 13.8 0.2 2 8.2 0.1 2.7 2 1 0 2 2 2 0 PUB domain UN_NPL4 PF11543.3 GAM22041.1 - 0.12 12.7 0.2 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 XPC-binding PF09280.6 GAM22041.1 - 5.6 6.5 35.8 2.5 7.6 4.0 5.8 4 2 1 5 5 5 0 XPC-binding domain DUF2360 PF10152.4 GAM22042.1 - 9.1e-41 139.5 0.3 9.1e-41 139.5 0.2 3.5 2 2 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) Ras PF00071.17 GAM22043.1 - 7.4e-43 145.7 0.0 1.4e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM22043.1 - 2.9e-15 56.7 0.1 5.4e-10 39.8 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein PH PF00169.24 GAM22043.1 - 2.6e-08 34.0 0.4 2.6e-08 34.0 0.3 2.2 3 0 0 3 3 3 1 PH domain PH_6 PF15406.1 GAM22043.1 - 5.1e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_5 PF15405.1 GAM22043.1 - 0.011 15.6 0.2 0.011 15.6 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain OHCU_decarbox PF09349.5 GAM22043.1 - 0.05 13.9 0.1 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 OHCU decarboxylase ABC_membrane PF00664.18 GAM22044.1 - 9e-14 51.5 20.0 7.2e-09 35.4 6.2 2.5 1 1 1 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM22044.1 - 8e-11 42.3 0.0 8e-11 42.3 0.0 2.3 2 1 0 2 2 2 1 ABC transporter Herpes_UL45 PF05473.7 GAM22044.1 - 0.022 14.1 0.3 0.041 13.2 0.2 1.4 1 0 0 1 1 1 0 UL45 protein DUF1693 PF07984.7 GAM22045.1 - 3.6e-24 85.4 4.1 9.3e-19 67.7 1.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1693) COX15-CtaA PF02628.10 GAM22046.1 - 1.5e-91 306.4 7.4 1.9e-91 306.1 5.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Protamine_P2 PF00841.14 GAM22046.1 - 0.13 12.8 2.6 0.24 11.9 1.8 1.4 1 0 0 1 1 1 0 Sperm histone P2 FAT PF02259.18 GAM22047.1 - 1.3e-109 366.4 0.6 1.3e-109 366.4 0.4 3.1 3 1 0 3 3 3 1 FAT domain DUF3385 PF11865.3 GAM22047.1 - 1.8e-62 209.9 0.1 2.5e-58 196.5 0.0 4.2 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 GAM22047.1 - 1.8e-60 204.3 1.1 3.7e-60 203.3 0.8 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 GAM22047.1 - 1.3e-40 137.5 0.3 1.3e-40 137.5 0.2 3.6 4 0 0 4 4 3 1 Rapamycin binding domain HEAT_2 PF13646.1 GAM22047.1 - 1.3e-26 92.6 8.9 0.00032 20.9 0.0 10.5 6 2 4 10 10 10 7 HEAT repeats HEAT PF02985.17 GAM22047.1 - 2.7e-16 58.1 20.5 0.022 14.7 0.0 12.6 14 0 0 14 14 13 2 HEAT repeat FATC PF02260.15 GAM22047.1 - 2.3e-15 55.6 2.2 2.8e-15 55.4 0.1 2.3 2 0 0 2 2 2 1 FATC domain HEAT_EZ PF13513.1 GAM22047.1 - 1.4e-12 47.7 20.4 0.0012 19.2 0.1 11.1 10 2 4 14 14 12 4 HEAT-like repeat Adaptin_N PF01602.15 GAM22047.1 - 1.9e-10 39.7 6.1 8.2e-08 31.0 0.1 4.4 5 0 0 5 5 5 2 Adaptin N terminal region Cnd1 PF12717.2 GAM22047.1 - 4.4e-06 26.6 1.9 0.89 9.3 0.0 5.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 GAM22047.1 - 7.5e-05 22.6 6.4 1.3 8.9 0.0 6.6 7 0 0 7 7 6 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 GAM22047.1 - 0.00021 21.6 3.5 32 4.9 0.0 6.5 7 1 0 7 7 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM22047.1 - 0.0015 17.8 0.3 0.26 10.6 0.0 4.6 5 1 0 5 5 5 1 CLASP N terminal API5 PF05918.6 GAM22047.1 - 0.0076 14.7 0.1 0.019 13.5 0.1 1.6 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) TPR_7 PF13176.1 GAM22047.1 - 0.11 12.3 2.9 0.51 10.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM22047.1 - 0.11 12.7 0.0 2.5 8.5 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 GAM22048.1 - 1.7e-21 76.1 0.1 2.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM22048.1 - 3.7e-07 31.0 0.0 7.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Vault PF01505.13 GAM22049.1 - 9e-67 220.8 0.2 1.3e-14 53.9 0.0 6.2 6 0 0 6 6 6 5 Major Vault Protein repeat MVP_shoulder PF11978.3 GAM22049.1 - 7.2e-53 177.4 0.4 1.4e-52 176.5 0.3 1.5 1 0 0 1 1 1 1 Shoulder domain DUF3601 PF12208.3 GAM22049.1 - 0.016 15.1 0.0 3.8 7.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3601) T2SI PF02501.12 GAM22049.1 - 0.19 11.6 5.7 0.31 11.0 0.1 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein I Frizzled PF01534.12 GAM22050.1 - 1e-07 31.1 10.2 1.4e-07 30.6 7.0 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.6 GAM22050.1 - 1.1e-06 27.7 10.9 1.8e-06 27.0 7.6 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM22050.1 - 1.2e-06 27.7 9.9 1.2e-06 27.7 6.9 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) MerT PF02411.10 GAM22050.1 - 0.014 15.1 0.9 0.042 13.6 0.6 1.8 1 0 0 1 1 1 0 MerT mercuric transport protein 7TM_GPCR_Str PF10326.4 GAM22050.1 - 0.12 11.4 11.2 0.014 14.5 4.4 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str DUF4131 PF13567.1 GAM22050.1 - 0.19 11.1 1.7 0.6 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PTR2 PF00854.16 GAM22051.1 - 2.3e-68 230.6 21.7 2.7e-65 220.5 4.7 3.0 1 1 2 3 3 3 3 POT family HVSL PF09749.4 GAM22052.1 - 2.2e-35 121.8 0.4 3.8e-35 121.0 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 GAM22052.1 - 0.00029 20.5 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Nop14 PF04147.7 GAM22052.1 - 0.047 11.6 8.7 0.055 11.3 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family LigT_PEase PF02834.11 GAM22052.1 - 0.079 12.9 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 LigT like Phosphoesterase CDC27 PF09507.5 GAM22052.1 - 0.63 9.2 10.3 0.87 8.7 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 GAM22053.1 - 4.2 5.5 5.0 6.5 4.9 3.4 1.4 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 GAM22054.1 - 6.9 6.7 8.3 15 5.5 1.8 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1764 PF08576.5 GAM22054.1 - 9.4 7.0 9.2 4.6 8.0 2.7 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) MIF4G_like_2 PF09090.6 GAM22055.1 - 8.7e-42 143.0 1.0 1.9e-41 142.0 0.7 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.6 GAM22055.1 - 5.6e-33 113.9 6.5 3.5e-32 111.3 1.5 3.0 2 1 1 3 3 3 1 MIF4G like MIF4G PF02854.14 GAM22055.1 - 2.3e-17 63.0 3.9 2.3e-17 63.0 2.7 2.5 3 0 0 3 3 3 1 MIF4G domain DinB_2 PF12867.2 GAM22055.1 - 0.1 12.9 0.5 3.8 7.8 0.1 2.5 2 0 0 2 2 2 0 DinB superfamily LRR_4 PF12799.2 GAM22056.1 - 3.5e-15 55.2 58.6 0.0033 17.0 0.1 9.8 7 2 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM22056.1 - 2.7e-13 48.4 67.5 0.083 13.0 0.0 15.2 15 1 0 15 15 15 8 Leucine Rich repeat LRR_8 PF13855.1 GAM22056.1 - 1e-07 31.5 67.5 0.021 14.5 4.8 9.1 5 4 4 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 GAM22056.1 - 0.0023 17.7 48.7 5.3 7.4 0.0 14.2 14 2 0 14 14 14 3 Leucine Rich Repeat DS PF01916.12 GAM22056.1 - 0.11 11.6 0.4 0.43 9.6 0.1 1.9 1 1 0 2 2 2 0 Deoxyhypusine synthase AAA_23 PF13476.1 GAM22057.1 - 9.4e-12 45.6 41.1 9.4e-12 45.6 28.5 7.5 1 1 1 3 3 2 1 AAA domain AAA_21 PF13304.1 GAM22057.1 - 3.3e-11 43.6 7.7 2.5e-05 24.4 0.8 3.9 3 1 0 3 3 3 2 AAA domain AAA_13 PF13166.1 GAM22057.1 - 4.5e-11 41.9 129.5 0.00045 18.8 9.8 7.9 2 1 4 6 6 6 4 AAA domain SbcCD_C PF13558.1 GAM22057.1 - 1.5e-08 34.4 0.0 4.8e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.9 GAM22057.1 - 1.8e-05 24.1 1.9 0.00015 21.1 0.1 3.8 2 0 0 2 2 2 1 Rad50 zinc hook motif AAA_15 PF13175.1 GAM22057.1 - 0.00025 20.2 20.3 0.00025 20.2 14.1 4.6 2 2 1 3 3 2 1 AAA ATPase domain SMC_N PF02463.14 GAM22057.1 - 0.00025 20.3 51.1 0.0014 17.9 35.4 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM22057.1 - 0.0033 16.9 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.4 GAM22057.1 - 0.0039 17.0 11.5 0.0039 17.0 8.0 9.5 4 2 6 11 11 11 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.8 GAM22057.1 - 0.0044 17.0 7.9 0.0044 17.0 5.5 10.1 5 3 5 10 10 9 1 DivIVA protein ABC_tran PF00005.22 GAM22057.1 - 0.0061 16.8 0.0 0.0061 16.8 0.0 8.1 2 1 0 3 3 1 1 ABC transporter HALZ PF02183.13 GAM22057.1 - 0.012 15.3 1.8 0.012 15.3 1.2 8.0 8 1 0 9 9 9 0 Homeobox associated leucine zipper Methyltransf_12 PF08242.7 GAM22057.1 - 0.32 11.4 2.7 47 4.5 0.1 3.7 2 0 0 2 2 2 0 Methyltransferase domain AAA_22 PF13401.1 GAM22057.1 - 1.1 9.3 0.0 1.1 9.3 0.0 5.2 6 0 0 6 6 6 0 AAA domain MAT1 PF06391.8 GAM22058.1 - 3.1e-30 105.2 22.8 4e-30 104.8 15.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 GAM22058.1 - 1.8e-05 24.3 7.6 0.00026 20.6 5.9 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM22058.1 - 6.9e-05 22.5 5.1 0.00014 21.5 3.6 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM22058.1 - 7.9e-05 22.2 7.4 0.00076 19.0 5.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM22058.1 - 8.3e-05 22.5 6.0 0.0034 17.3 5.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM22058.1 - 0.00028 20.4 9.3 0.00055 19.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM22058.1 - 0.029 14.2 7.2 0.058 13.2 5.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM22058.1 - 0.037 13.7 4.7 0.13 12.0 3.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF2318 PF10080.4 GAM22058.1 - 0.061 13.0 4.5 1 9.1 1.0 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Rrn6 PF10214.4 GAM22058.1 - 0.12 10.4 15.2 0.048 11.7 9.0 1.4 1 1 1 2 2 2 0 RNA polymerase I-specific transcription-initiation factor FYVE PF01363.16 GAM22058.1 - 0.67 9.8 4.6 1.9 8.4 3.2 1.9 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_1 PF14446.1 GAM22058.1 - 1.5 8.6 6.2 0.12 12.0 0.9 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L18p PF00861.17 GAM22059.1 - 7.4e-42 142.3 0.0 7.4e-42 142.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 GAM22059.1 - 1.4e-30 105.6 2.5 1.4e-30 105.6 1.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 GAM22059.1 - 0.093 12.7 0.0 0.67 10.0 0.0 2.3 1 1 1 2 2 2 0 Threonine synthase N terminus EGF_2 PF07974.8 GAM22061.1 - 0.002 18.2 11.2 0.0033 17.5 7.8 1.4 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM22061.1 - 0.066 13.3 8.7 0.16 12.1 6.0 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.22 GAM22061.1 - 0.083 12.8 4.5 0.16 12.0 3.1 1.4 1 0 0 1 1 1 0 EGF-like domain PepSY_TM_3 PF13706.1 GAM22061.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix EGF_2 PF07974.8 GAM22062.1 - 0.014 15.5 13.6 0.032 14.3 9.4 1.6 1 0 0 1 1 1 0 EGF-like domain SLH PF00395.15 GAM22062.1 - 0.073 12.8 0.1 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 S-layer homology domain EGF PF00008.22 GAM22062.1 - 0.088 12.8 9.5 0.17 11.8 6.6 1.5 1 0 0 1 1 1 0 EGF-like domain Syndecan PF01034.15 GAM22062.1 - 0.18 11.4 0.4 0.37 10.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain hEGF PF12661.2 GAM22062.1 - 0.2 11.8 4.3 0.44 10.7 2.9 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF Vpu PF00558.14 GAM22062.1 - 0.75 9.3 2.6 1.6 8.3 1.8 1.5 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.8 GAM22063.1 - 0.0034 17.5 10.9 0.0067 16.5 7.6 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM22063.1 - 0.43 10.7 6.1 0.94 9.7 4.3 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF Kelch_4 PF13418.1 GAM22064.1 - 1.3e-13 50.4 7.8 3.2e-05 23.5 0.1 5.2 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM22064.1 - 1.6e-13 50.1 7.2 0.0022 18.1 0.0 6.1 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 GAM22064.1 - 3.7e-11 42.3 5.6 0.0032 16.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 GAM22064.1 - 8.3e-10 38.5 3.8 0.034 14.3 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM22064.1 - 0.0023 17.6 6.6 6.9 6.6 0.0 4.8 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 GAM22064.1 - 0.0044 16.9 4.3 1.2 9.1 0.0 3.6 3 0 0 3 3 3 2 Kelch motif GFA PF04828.9 GAM22065.1 - 2.9e-09 36.7 0.6 2.9e-09 36.7 0.4 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 GAM22065.1 - 0.036 13.9 3.2 0.063 13.2 1.1 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC zf-CSL PF05207.8 GAM22065.1 - 0.16 11.5 3.6 0.1 12.0 0.8 1.8 2 0 0 2 2 2 0 CSL zinc finger NOB1_Zn_bind PF08772.6 GAM22065.1 - 0.28 11.0 0.1 0.28 11.0 0.0 2.3 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like RRN7 PF11781.3 GAM22065.1 - 8.4 5.9 8.9 4.9 6.7 2.3 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 FNIP PF05725.7 GAM22066.1 - 1.2e-13 50.7 4.3 3.2e-09 36.5 0.9 3.2 2 1 1 3 3 3 2 FNIP Repeat GFA PF04828.9 GAM22066.1 - 0.0003 20.6 1.1 0.0003 20.6 0.7 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 GAM22066.1 - 0.049 13.1 1.5 0.12 11.9 1.0 1.6 1 0 0 1 1 1 0 CSL zinc finger Cys_rich_CWC PF14375.1 GAM22066.1 - 0.054 13.4 1.6 0.054 13.4 1.1 2.0 2 0 0 2 2 2 0 Cysteine-rich CWC zf-RING_5 PF14634.1 GAM22066.1 - 0.24 11.1 7.6 0.88 9.3 5.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain GFA PF04828.9 GAM22067.1 - 9e-06 25.5 5.7 9e-06 25.5 3.9 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 GAM22067.1 - 0.027 14.4 1.8 0.027 14.4 1.2 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC zf-RING_2 PF13639.1 GAM22067.1 - 0.029 14.1 0.8 0.029 14.1 0.6 2.8 3 1 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.1 GAM22067.1 - 0.13 12.0 12.7 0.16 11.6 6.9 2.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-CCHC_4 PF14392.1 GAM22067.1 - 0.14 11.8 4.9 0.14 11.8 1.6 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_3 PF13920.1 GAM22067.1 - 0.16 11.6 9.0 0.57 9.8 1.1 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CSL PF05207.8 GAM22067.1 - 4.1 6.9 8.1 0.27 10.7 1.5 2.0 2 0 0 2 2 2 0 CSL zinc finger zf-C3HC4 PF00097.20 GAM22067.1 - 4.6 6.9 12.0 0.14 11.8 1.2 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GFA PF04828.9 GAM22068.1 - 1.8e-06 27.8 2.7 1.8e-06 27.8 1.9 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 GAM22068.1 - 0.0092 15.4 4.0 0.0092 15.4 2.8 1.9 2 0 0 2 2 2 1 CSL zinc finger PI3K_rbd PF00794.13 GAM22068.1 - 0.014 15.2 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain Zn_Tnp_IS1 PF03811.8 GAM22068.1 - 0.031 13.7 0.6 0.031 13.7 0.4 2.5 2 0 0 2 2 2 0 InsA N-terminal domain Prim_Zn_Ribbon PF08273.7 GAM22068.1 - 0.1 12.7 0.7 0.1 12.7 0.5 2.5 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase RCC1 PF00415.13 GAM22069.1 - 3.9e-69 228.6 8.5 2.2e-15 56.5 0.0 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM22069.1 - 3.1e-36 122.2 27.5 1.6e-08 33.9 0.0 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAM22069.1 - 4.5e-19 68.4 2.8 2.1e-15 56.6 0.5 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.1 GAM22069.1 - 9.8e-09 35.1 0.0 2.4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM22069.1 - 1.6e-05 25.1 0.0 7.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22069.1 - 2.9e-05 24.4 0.2 0.0039 17.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM22069.1 - 3.9e-05 23.2 0.0 0.00018 21.1 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 GAM22069.1 - 0.0012 18.8 0.0 0.012 15.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Mucin PF01456.12 GAM22069.1 - 0.011 15.4 7.7 0.028 14.1 5.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein LAGLIDADG_2 PF03161.8 GAM22069.1 - 0.082 12.8 1.6 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family Ceramidase PF05875.7 GAM22071.1 - 2.6e-39 134.9 13.5 4.4e-39 134.2 9.3 1.3 1 0 0 1 1 1 1 Ceramidase EGF_2 PF07974.8 GAM22071.1 - 0.012 15.7 14.4 0.029 14.5 10.0 1.6 1 0 0 1 1 1 0 EGF-like domain WD40 PF00400.27 GAM22072.1 - 3.9e-09 36.0 7.5 5.1e-06 26.1 0.2 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat eIF2A PF08662.6 GAM22072.1 - 4.3e-06 26.5 0.2 0.012 15.3 0.0 3.3 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAM22072.1 - 0.00054 18.3 0.2 0.81 7.9 0.0 3.0 2 1 1 3 3 3 3 Cytochrome D1 heme domain Glu_cyclase_2 PF05096.7 GAM22072.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutamine cyclotransferase Coatomer_WDAD PF04053.9 GAM22072.1 - 0.056 12.2 0.0 0.44 9.2 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Rifin_STEVOR PF02009.11 GAM22073.1 - 0.11 12.1 1.6 0.15 11.7 0.1 1.8 1 1 1 2 2 2 0 Rifin/stevor family ODV-E18 PF10717.4 GAM22073.1 - 0.55 9.7 6.3 0.33 10.4 0.6 3.2 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 GRAM PF02893.15 GAM22074.1 - 9.6e-11 41.0 0.3 2.3e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 GRAM domain HEM4 PF02602.10 GAM22075.1 - 1.9e-26 92.7 0.0 2.3e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD G-alpha PF00503.15 GAM22076.1 - 3.3e-69 233.4 3.1 3.9e-69 233.2 2.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM22076.1 - 1.5e-08 34.1 1.2 2.9e-05 23.3 0.0 2.8 2 1 1 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM22076.1 - 0.00053 19.1 0.9 0.69 8.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM22076.1 - 0.0046 16.8 0.0 0.85 9.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 GAM22076.1 - 0.0058 17.1 0.1 5.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM22076.1 - 0.019 14.5 0.2 0.047 13.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.4 GAM22076.1 - 0.034 13.0 0.2 0.062 12.2 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TMPIT PF07851.8 GAM22077.1 - 0.059 12.4 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein Dyp_perox PF04261.7 GAM22079.1 - 2.6e-87 292.4 0.0 3.1e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF3430 PF11912.3 GAM22080.1 - 0.0035 17.1 1.9 0.0035 17.1 1.3 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) Sld5 PF05916.6 GAM22081.1 - 0.0002 21.6 0.1 0.00091 19.5 0.0 1.9 2 0 0 2 2 2 1 GINS complex protein RF-1 PF00472.15 GAM22082.1 - 2.3e-35 120.8 1.3 5.3e-35 119.6 0.9 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 GAM22082.1 - 8e-26 90.0 1.1 8e-26 90.0 0.8 2.0 2 0 0 2 2 2 1 PCRF domain DUF386 PF04074.7 GAM22082.1 - 0.029 13.8 0.2 0.16 11.4 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF386) DUF308 PF03729.8 GAM22083.1 - 0.0043 17.0 7.7 0.036 14.0 1.0 2.9 2 1 1 3 3 3 2 Short repeat of unknown function (DUF308) DUF3185 PF11381.3 GAM22083.1 - 0.033 13.9 0.2 0.088 12.5 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) DUF2207 PF09972.4 GAM22083.1 - 0.11 11.0 3.7 0.045 12.3 1.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Polysacc_synt_3 PF13440.1 GAM22083.1 - 0.15 11.5 13.5 0.39 10.1 9.2 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1422 PF07226.6 GAM22083.1 - 0.15 11.7 3.3 0.18 11.5 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1422) DUF1282 PF06930.7 GAM22083.1 - 0.45 10.1 12.0 0.13 11.9 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) PspC PF04024.7 GAM22083.1 - 0.48 9.9 13.3 1.2 8.6 0.2 3.2 3 1 0 3 3 3 0 PspC domain CD20 PF04103.10 GAM22083.1 - 0.53 10.2 10.6 1.1 9.2 7.4 1.5 1 1 0 1 1 1 0 CD20-like family Tetraspannin PF00335.15 GAM22083.1 - 0.76 9.0 15.5 0.085 12.1 6.4 1.9 1 1 1 2 2 2 0 Tetraspanin family PgaD PF13994.1 GAM22083.1 - 1 8.8 7.5 4.7 6.6 0.3 2.5 2 1 1 3 3 3 0 PgaD-like protein SdpI PF13630.1 GAM22083.1 - 1.2 8.9 13.9 0.097 12.3 3.0 2.9 2 1 1 3 3 3 0 SdpI/YhfL protein family DUF1600 PF07667.6 GAM22083.1 - 2.5 8.2 10.1 2.1 8.4 4.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1600) DUF4181 PF13789.1 GAM22083.1 - 6.7 6.6 11.2 12 5.8 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4181) CoA_binding_3 PF13727.1 GAM22083.1 - 8.1 6.2 7.7 0.79 9.5 1.9 1.8 1 1 1 2 2 2 0 CoA-binding domain Isy1 PF06246.7 GAM22084.1 - 4.6e-81 271.9 14.4 5.3e-81 271.7 10.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Brix PF04427.13 GAM22085.1 - 9.9e-49 165.5 1.1 9.9e-49 165.5 0.7 1.5 2 0 0 2 2 2 1 Brix domain OmpH PF03938.9 GAM22085.1 - 0.44 10.4 14.0 2.1 8.2 6.6 2.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) IMPDH PF00478.20 GAM22085.1 - 1.5 7.6 6.6 0.13 11.1 0.3 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain CDC45 PF02724.9 GAM22086.1 - 0.00011 20.4 4.1 0.00013 20.2 2.8 1.1 1 0 0 1 1 1 1 CDC45-like protein eIF-3c_N PF05470.7 GAM22086.1 - 0.021 12.9 1.4 0.021 12.9 1.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.6 GAM22086.1 - 1.4 6.9 11.5 1.7 6.6 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Metallophos PF00149.23 GAM22088.1 - 2.7e-09 36.7 1.4 1.3e-07 31.2 0.9 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM22088.1 - 3.8e-05 23.5 0.0 6.5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ASF1_hist_chap PF04729.8 GAM22089.1 - 3e-64 215.3 0.0 3.3e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Zip PF02535.17 GAM22090.1 - 8.1e-47 159.7 11.9 1e-46 159.4 8.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Metallophos PF00149.23 GAM22091.1 - 1.1e-42 145.7 1.1 1.3e-42 145.4 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CDC45 PF02724.9 GAM22092.1 - 4e-164 547.0 9.9 4.9e-164 546.7 6.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 GAM22092.1 - 0.041 12.3 24.3 0.058 11.8 16.8 1.1 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 GAM22092.1 - 0.05 13.1 28.2 0.086 12.4 19.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2890 PF11081.3 GAM22092.1 - 0.11 12.5 16.2 0.21 11.6 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 GAM22092.1 - 0.38 8.6 30.6 0.57 8.0 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 GAM22092.1 - 0.58 9.0 21.0 0.99 8.3 14.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.7 GAM22092.1 - 0.85 8.8 29.6 1.4 8.1 20.5 1.2 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 GAM22092.1 - 4.5 6.5 18.4 8.9 5.6 12.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 GAM22092.1 - 5.9 4.6 7.5 10 3.8 5.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_2 PF12796.2 GAM22093.1 - 4.9e-25 87.6 1.3 2.4e-06 27.7 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22093.1 - 6.8e-19 67.8 10.6 1.5e-05 25.3 0.2 7.3 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22093.1 - 7.4e-14 51.4 16.0 0.22 11.8 0.1 9.3 3 2 6 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22093.1 - 1.1e-11 43.7 10.5 0.73 10.2 0.1 8.6 7 1 1 8 8 8 4 Ankyrin repeat Ank PF00023.25 GAM22093.1 - 4.5e-06 26.2 15.6 1.1 9.2 0.0 8.6 9 1 0 9 9 9 2 Ankyrin repeat zf-LITAF-like PF10601.4 GAM22094.1 - 3.4e-23 81.2 8.2 5.2e-23 80.6 5.7 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain HypA PF01155.14 GAM22094.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.3 1 1 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-UDP PF14569.1 GAM22094.1 - 0.12 12.1 0.7 0.24 11.1 0.5 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger OrfB_Zn_ribbon PF07282.6 GAM22094.1 - 0.17 11.5 1.2 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 GAM22094.1 - 0.23 11.2 2.4 13 5.6 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM22094.1 - 0.25 10.8 7.3 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RecR PF02132.10 GAM22094.1 - 0.25 10.7 2.5 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 RecR protein DZR PF12773.2 GAM22094.1 - 0.31 10.8 4.3 1.4 8.7 3.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM22094.1 - 0.36 10.1 3.6 9.7 5.5 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.7 GAM22094.1 - 0.41 10.3 4.7 8.2 6.1 0.3 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-IS66 PF13005.2 GAM22094.1 - 0.67 9.9 4.5 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 Rubredoxin PF00301.15 GAM22094.1 - 2.5 8.0 5.8 9.6 6.1 0.0 3.2 3 1 0 3 3 3 0 Rubredoxin zf-C4_Topoisom PF01396.14 GAM22094.1 - 3.4 7.2 6.8 1.7 8.2 0.1 2.7 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF814 PF05670.8 GAM22095.1 - 2.5e-25 88.1 0.0 5.5e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) MAP7 PF05672.6 GAM22095.1 - 0.041 13.2 16.0 0.06 12.7 11.1 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family FtsK_SpoIIIE PF01580.13 GAM22095.1 - 0.8 9.1 3.4 1.1 8.6 2.4 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Kelch_6 PF13964.1 GAM22096.1 - 1.7e-08 34.2 7.2 0.00025 21.0 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM22096.1 - 1.2e-05 25.2 0.1 0.57 10.4 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM22096.1 - 3.4e-05 23.5 6.4 0.005 16.5 0.0 3.9 3 2 1 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22096.1 - 0.006 16.1 4.6 1.1 8.7 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM22096.1 - 0.82 9.5 3.3 11 6.0 0.5 3.6 3 1 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 GAM22096.1 - 0.88 9.6 6.2 3.6 7.6 0.1 3.1 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 GAM22097.1 - 2.9e-10 39.8 3.9 0.0028 17.7 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 GAM22097.1 - 2.2e-06 27.3 8.0 0.0011 18.7 0.1 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM22097.1 - 9.2e-06 25.6 1.3 0.25 11.5 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22097.1 - 0.00031 20.2 3.7 0.32 10.5 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM22097.1 - 0.0036 17.2 1.4 0.095 12.6 0.2 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 GAM22097.1 - 0.0056 16.4 0.8 5.6 6.8 0.0 3.9 5 0 0 5 5 5 1 Kelch motif Pkinase PF00069.20 GAM22098.1 - 3e-63 213.4 0.0 3.9e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22098.1 - 7.2e-50 169.4 0.0 1.3e-49 168.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22098.1 - 1.9e-05 23.7 0.0 0.00072 18.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM22098.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM22098.1 - 0.15 11.3 0.1 0.58 9.4 0.1 1.8 1 1 1 2 2 2 0 RIO1 family TPP1 PF10341.4 GAM22100.1 - 0.0025 17.7 0.1 0.0025 17.7 0.1 2.8 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD DUF1632 PF07857.7 GAM22101.1 - 0.046 12.9 0.1 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 CEO family (DUF1632) Caudo_TAP PF02413.12 GAM22101.1 - 0.41 10.8 4.5 0.21 11.7 1.0 1.9 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Maf PF02545.9 GAM22102.1 - 4.9e-53 179.1 0.0 6.1e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein AD PF09793.4 GAM22102.1 - 0.037 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain Peptidase_C12 PF01088.16 GAM22103.1 - 9.9e-70 234.0 0.0 1.5e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribonuc_2-5A PF06479.7 GAM22103.1 - 0.018 14.8 0.4 0.21 11.4 0.0 2.5 3 0 0 3 3 3 0 Ribonuclease 2-5A HsbA PF12296.3 GAM22104.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A GATase PF00117.23 GAM22105.1 - 6e-39 133.4 0.0 1.2e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 GAM22105.1 - 7.4e-28 96.1 1.3 6.4e-27 93.1 0.9 2.7 1 1 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 GAM22105.1 - 6.2e-14 51.9 0.0 1.2e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 GAM22105.1 - 1.3e-10 40.5 0.1 1.4e-07 30.6 0.1 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 GAM22105.1 - 4.3e-07 29.4 0.1 2e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 GAM22105.1 - 2.3e-05 23.9 0.0 7e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 GAM22105.1 - 3.9e-05 22.8 0.0 7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.11 GAM22105.1 - 9.5e-05 21.0 0.0 0.00079 18.0 0.0 2.1 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 GAM22105.1 - 0.00026 20.5 0.1 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.14 GAM22105.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 GAM22105.1 - 0.055 12.9 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 PP-loop family DUF2073 PF09846.4 GAM22105.1 - 0.093 12.3 0.6 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2073) FNIP PF05725.7 GAM22106.1 - 6.1e-60 198.9 38.8 1.2e-14 53.9 0.4 9.4 5 2 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM22106.1 - 0.0063 16.4 4.7 10 6.1 0.1 5.8 3 2 4 7 7 7 1 Protein of unknown function (DUF1769) Kelch_6 PF13964.1 GAM22107.1 - 1.1e-07 31.7 9.5 0.0027 17.8 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM22107.1 - 7.7e-05 22.7 1.3 2.8 8.2 0.0 4.5 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22107.1 - 0.00025 20.4 7.9 0.087 12.3 0.3 4.1 4 0 0 4 4 4 2 Kelch motif DUF1664 PF07889.7 GAM22107.1 - 0.0081 15.9 11.6 0.015 15.0 2.3 3.1 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Kelch_4 PF13418.1 GAM22107.1 - 0.011 15.4 0.1 0.011 15.4 0.1 4.8 5 1 0 5 5 5 0 Galactose oxidase, central domain ALIX_LYPXL_bnd PF13949.1 GAM22107.1 - 0.017 14.1 2.1 0.032 13.2 0.9 1.6 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Spc7_C2 PF15577.1 GAM22107.1 - 0.28 10.8 3.3 3 7.5 0.1 2.7 2 0 0 2 2 2 0 Spc7_C2 DUF3439 PF11921.3 GAM22107.1 - 0.4 10.4 5.2 0.82 9.4 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NPV_P10 PF05531.7 GAM22107.1 - 0.54 10.5 8.7 4.1 7.7 1.6 3.1 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 GAM22107.1 - 0.71 9.4 8.6 0.57 9.7 2.7 2.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1268 PF06896.6 GAM22107.1 - 0.93 9.8 6.6 0.28 11.5 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) Baculo_PEP_C PF04513.7 GAM22107.1 - 1.3 8.8 11.3 1.1 9.0 2.8 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.1 GAM22107.1 - 1.5 9.2 5.7 11 6.3 1.5 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin_2 PF14523.1 GAM22107.1 - 8.3 6.5 13.8 19 5.3 4.1 3.2 2 1 1 3 3 3 0 Syntaxin-like protein Kelch_4 PF13418.1 GAM22108.1 - 2.7e-10 39.8 0.1 0.00085 19.0 0.0 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM22108.1 - 2.5e-09 36.8 5.0 0.086 13.0 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM22108.1 - 0.0015 18.6 0.2 0.71 10.1 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM22108.1 - 0.0025 17.7 1.1 0.064 13.2 0.3 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 GAM22108.1 - 0.0032 16.9 4.1 8.6 5.9 0.0 4.6 4 0 0 4 4 4 2 Kelch motif zf-B_box PF00643.19 GAM22108.1 - 0.068 13.0 3.8 0.12 12.2 2.6 1.5 1 0 0 1 1 1 0 B-box zinc finger Baculo_PEP_C PF04513.7 GAM22108.1 - 0.52 10.1 7.5 0.51 10.1 0.8 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM22108.1 - 1 9.1 3.8 1.6 8.5 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 GAM22109.1 - 2.1e-76 256.5 0.0 2.3e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22109.1 - 5.2e-33 114.2 0.0 8.6e-33 113.4 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM22109.1 - 0.00053 19.7 0.0 0.014 15.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM22109.1 - 0.001 17.9 0.0 0.0019 17.0 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 GAM22109.1 - 0.0041 16.1 0.0 0.01 14.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM22109.1 - 0.045 12.7 0.1 0.074 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Far-17a_AIG1 PF04750.9 GAM22110.1 - 1.7e-24 86.0 15.1 3.6e-22 78.5 10.5 2.0 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein I_LWEQ PF01608.12 GAM22111.1 - 4.3e-49 166.3 15.6 4.3e-49 166.3 10.8 8.0 5 3 2 8 8 8 4 I/LWEQ domain VHP PF02209.14 GAM22111.1 - 2.1e-14 52.9 2.5 4.7e-14 51.7 1.7 1.6 1 0 0 1 1 1 1 Villin headpiece domain VBS PF08913.5 GAM22111.1 - 1.6e-07 31.6 55.9 2.7e-06 27.6 3.3 7.1 7 0 0 7 7 7 4 Vinculin Binding Site Talin_middle PF09141.5 GAM22111.1 - 0.0052 16.4 4.2 0.0052 16.4 2.9 8.8 5 3 1 8 8 8 5 Talin, middle domain FERM_M PF00373.13 GAM22112.1 - 1.5e-23 83.3 0.0 1.5e-23 83.3 0.0 3.4 4 0 0 4 4 4 1 FERM central domain FERM_N PF09379.5 GAM22112.1 - 4.1e-20 71.6 0.1 2e-19 69.4 0.1 2.3 2 0 0 2 2 2 1 FERM N-terminal domain I_LWEQ PF01608.12 GAM22112.1 - 3.5e-09 36.7 112.5 0.0024 17.8 3.3 12.5 4 2 12 16 16 16 11 I/LWEQ domain VBS PF08913.5 GAM22112.1 - 4.6e-06 26.8 61.1 0.0014 18.8 0.9 9.2 5 2 0 5 5 5 2 Vinculin Binding Site RA PF00788.18 GAM22112.1 - 0.012 16.1 0.1 0.075 13.5 0.0 2.6 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain DUF3610 PF12272.3 GAM22112.1 - 0.018 14.7 0.0 0.07 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) DUF4496 PF14908.1 GAM22113.1 - 9.7 6.0 13.3 0.13 12.1 2.4 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4496) Vps52 PF04129.7 GAM22114.1 - 1e-80 271.7 30.8 1e-80 271.7 21.4 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family Cep57_MT_bd PF06657.8 GAM22114.1 - 0.00019 21.3 1.2 0.00072 19.4 0.8 2.0 1 0 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 Sec3_C PF09763.4 GAM22114.1 - 0.0055 14.9 32.4 0.34 9.0 17.6 4.1 1 1 1 2 2 2 2 Exocyst complex component Sec3 Ded_cyto PF06920.8 GAM22115.1 - 1.2e-53 181.0 4.6 3.1e-53 179.6 3.2 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM22115.1 - 6.3e-46 156.3 1.6 1.8e-45 154.8 1.1 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.3 GAM22115.1 - 0.0052 16.5 0.0 0.47 10.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3398) FNIP PF05725.7 GAM22116.1 - 4e-13 49.0 0.7 5.1e-07 29.5 0.1 2.9 1 1 2 3 3 3 3 FNIP Repeat FNIP PF05725.7 GAM22117.1 - 1.2e-27 95.5 0.0 3e-09 36.6 0.0 3.8 2 1 2 5 5 5 4 FNIP Repeat DUF1769 PF08588.5 GAM22117.1 - 0.027 14.4 0.7 16 5.5 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1769) Ank_2 PF12796.2 GAM22118.1 - 4.8e-05 23.6 0.0 0.51 10.7 0.0 3.9 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22118.1 - 0.0021 18.0 0.0 25 5.4 0.0 5.2 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.25 GAM22118.1 - 0.023 14.4 0.1 6.1 6.8 0.0 3.8 4 1 0 4 4 4 0 Ankyrin repeat Fimbrial_PilY2 PF14481.1 GAM22119.1 - 0.12 11.7 0.2 7.2 6.0 0.0 2.4 1 1 1 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 P21-Arc PF04062.9 GAM22120.1 - 5.1e-67 225.0 0.0 6e-67 224.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Pkinase PF00069.20 GAM22121.1 - 7.8e-81 271.0 0.0 8.7e-81 270.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22121.1 - 4.3e-34 117.7 0.0 6.8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22121.1 - 0.00065 18.7 0.0 0.0024 16.8 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 GAM22121.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM22121.1 - 0.051 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAM22121.1 - 0.16 10.7 0.0 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 DUF3658 PF12395.3 GAM22123.1 - 0.051 13.1 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Myb_DNA-binding PF00249.26 GAM22125.1 - 1.4e-42 143.4 10.8 2.5e-14 53.0 1.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM22125.1 - 9.3e-33 112.1 17.1 5.2e-18 64.8 1.2 4.7 4 1 1 5 5 5 3 Myb-like DNA-binding domain Ank_2 PF12796.2 GAM22126.1 - 3e-50 168.5 9.2 2.8e-20 72.4 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22126.1 - 6.8e-47 157.0 13.0 4.7e-14 52.4 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM22126.1 - 2.7e-39 131.0 2.2 2.2e-07 30.3 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAM22126.1 - 5.5e-34 115.4 2.9 2.3e-08 34.0 0.1 5.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22126.1 - 6e-34 112.6 0.6 9.2e-07 28.5 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat PRP38 PF03371.10 GAM22128.1 - 1.2e-37 129.1 1.9 1.6e-37 128.7 1.3 1.1 1 0 0 1 1 1 1 PRP38 family DUF1497 PF07384.6 GAM22128.1 - 0.14 12.3 1.9 1 9.5 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1497) DUF155 PF02582.9 GAM22129.1 - 1.7e-42 145.2 0.2 2.6e-42 144.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF86 PF01934.12 GAM22129.1 - 0.08 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF86 PGM_PMM_I PF02878.11 GAM22130.1 - 4.4e-41 139.5 0.0 8.4e-41 138.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAM22130.1 - 1.2e-21 76.9 0.0 3.3e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 GAM22130.1 - 1.7e-15 57.0 0.0 3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 GAM22130.1 - 5.7e-07 29.4 0.0 2e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Guanylate_cyc PF00211.15 GAM22131.1 - 9e-54 181.6 0.1 1.3e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.8 GAM22131.1 - 0.0044 16.2 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 CHASE domain HLH PF00010.21 GAM22131.1 - 0.064 12.9 0.5 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain IMS PF00817.15 GAM22131.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family Glyco_hydro_28 PF00295.12 GAM22132.1 - 2e-37 128.8 0.4 4.4e-36 124.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 GAM22132.1 - 6.4e-06 26.0 3.9 9.7e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 Right handed beta helix region CLU PF13236.1 GAM22133.1 - 3e-56 190.3 0.0 9.9e-56 188.6 0.0 1.9 2 0 0 2 2 2 1 Clustered mitochondria TPR_12 PF13424.1 GAM22133.1 - 7.9e-40 134.6 14.5 5.1e-16 58.3 0.3 5.1 1 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 GAM22133.1 - 8e-19 66.9 0.0 2.8e-05 23.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM22133.1 - 3.8e-15 55.2 13.2 4.8e-06 26.1 0.3 4.6 2 1 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM22133.1 - 3.3e-12 45.4 15.5 0.029 13.9 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM22133.1 - 1.2e-10 40.4 13.5 0.029 14.2 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM22133.1 - 9.9e-10 37.4 6.0 0.0025 17.4 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat eIF3_p135 PF12807.2 GAM22133.1 - 9.5e-09 35.4 0.2 9.5e-09 35.4 0.1 3.3 2 1 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_6 PF13174.1 GAM22133.1 - 8.8e-07 28.9 1.8 4.4 7.9 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM22133.1 - 1.2e-06 27.8 23.4 0.0057 16.3 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM22133.1 - 4.5e-05 24.0 0.0 2.2 9.0 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM22133.1 - 8e-05 22.9 3.0 2.2 8.6 0.1 4.5 2 1 3 5 5 5 1 Tetratricopeptide repeat Med26 PF08711.6 GAM22133.1 - 0.03 13.8 0.1 0.13 11.7 0.1 2.1 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Apc3 PF12895.2 GAM22133.1 - 0.059 13.5 11.7 0.33 11.1 0.1 3.6 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 GAM22133.1 - 5.7 6.8 13.6 0.22 11.3 0.3 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat IPK PF03770.11 GAM22134.1 - 1e-48 165.5 0.1 1.1e-47 162.2 0.0 2.1 2 0 0 2 2 2 1 Inositol polyphosphate kinase MFS_1 PF07690.11 GAM22135.1 - 2.5e-38 131.6 34.8 1.6e-37 129.0 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM22135.1 - 5.4e-17 61.3 14.9 5.8e-13 48.0 2.7 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 GAM22135.1 - 1.2e-08 33.9 26.3 3.4e-06 25.9 18.9 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter Folate_carrier PF01770.13 GAM22135.1 - 0.012 14.1 0.2 0.012 14.1 0.1 2.0 2 0 0 2 2 2 0 Reduced folate carrier Kelch_6 PF13964.1 GAM22136.1 - 0.00022 21.2 0.2 0.00022 21.2 0.2 3.8 3 3 1 4 4 4 1 Kelch motif Kelch_5 PF13854.1 GAM22136.1 - 0.00031 20.5 0.1 0.0011 18.8 0.1 2.0 1 0 0 1 1 1 1 Kelch motif Kelch_4 PF13418.1 GAM22136.1 - 0.00048 19.8 0.4 0.0026 17.4 0.0 2.4 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22136.1 - 0.00089 18.7 0.2 0.003 17.0 0.2 1.9 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 GAM22136.1 - 0.00091 18.9 0.7 0.0033 17.1 0.0 2.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 GAM22136.1 - 0.0029 17.7 0.8 0.028 14.5 0.0 3.0 3 0 0 3 3 3 1 Galactose oxidase, central domain MutL_C PF08676.6 GAM22137.1 - 1.4e-26 92.8 0.0 3e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 GAM22137.1 - 4.3e-23 81.0 0.0 1.2e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAM22137.1 - 7.4e-12 45.0 0.0 1.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM22137.1 - 7.9e-10 38.4 0.1 2.4e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIID-31kDa PF02291.10 GAM22138.1 - 9.5e-43 145.0 1.3 1.9e-42 144.0 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 GAM22138.1 - 1.4e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 GAM22138.1 - 5.1e-05 23.3 0.0 0.00017 21.7 0.0 1.9 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID_30kDa PF03540.8 GAM22138.1 - 0.0034 17.1 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.19 GAM22138.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Macoilin PF09726.4 GAM22138.1 - 0.34 9.1 22.9 0.4 8.9 15.8 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 GAM22138.1 - 5.9 6.6 26.8 0.41 10.4 13.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cytochrom_B561 PF03188.11 GAM22139.1 - 6.4e-11 42.2 16.9 1.1e-10 41.4 11.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 GAM22139.1 - 6.8e-10 38.9 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF4181 PF13789.1 GAM22139.1 - 0.028 14.3 2.8 0.028 14.3 2.0 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4181) EVC2_like PF12297.3 GAM22139.1 - 0.055 12.1 0.6 0.083 11.5 0.4 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein YibE_F PF07907.6 GAM22139.1 - 8.9 5.4 21.4 2.1 7.4 4.5 2.1 2 0 0 2 2 2 0 YibE/F-like protein DUF2427 PF10348.4 GAM22139.1 - 9.9 5.7 12.8 23 4.6 6.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) bZIP_1 PF00170.16 GAM22140.1 - 2.3e-12 46.6 13.2 1.4e-10 40.9 5.0 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 GAM22140.1 - 0.00023 20.9 7.9 0.00023 20.9 5.5 2.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM22140.1 - 0.024 14.8 1.8 0.024 14.8 1.2 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4527 PF15030.1 GAM22140.1 - 0.86 8.8 6.7 0.67 9.2 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4527) BAF1_ABF1 PF04684.8 GAM22140.1 - 9 5.0 10.8 3.6 6.3 0.6 2.3 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Beach PF02138.13 GAM22142.1 - 8.9e-111 369.6 1.8 8.9e-111 369.6 1.3 3.3 5 0 0 5 5 5 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM22142.1 - 4.9e-17 61.7 0.4 8.9e-16 57.6 0.0 3.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 GAM22142.1 - 8e-09 35.0 2.0 4e-06 26.5 0.4 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1088 PF06469.6 GAM22142.1 - 0.0014 18.0 0.5 0.0014 18.0 0.3 2.1 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1088) N_methyl PF07963.7 GAM22142.1 - 0.21 11.3 3.9 7.8 6.4 1.0 2.6 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation motif RNA_pol_Rpc4 PF05132.9 GAM22143.1 - 3.8e-19 68.9 0.0 3.8e-19 68.9 0.0 3.3 4 1 0 4 4 4 1 RNA polymerase III RPC4 DUF726 PF05277.7 GAM22144.1 - 7.9e-63 212.4 0.5 1.5e-62 211.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF726) VPS9 PF02204.13 GAM22144.1 - 1.1e-08 35.0 0.6 1.1e-08 35.0 0.4 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Phage_int_SAM_4 PF13495.1 GAM22144.1 - 0.027 14.8 0.3 0.11 12.8 0.2 2.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain TFIIF_alpha PF05793.7 GAM22144.1 - 5.4 5.2 5.4 8.4 4.6 3.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ank_2 PF12796.2 GAM22145.1 - 0.0031 17.8 0.0 0.0066 16.7 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22145.1 - 0.1 13.1 0.1 2.3 8.8 0.0 2.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Med15_fungi PF05397.7 GAM22145.1 - 0.18 11.8 1.8 0.71 9.8 0.1 2.5 3 1 0 3 3 3 0 Mediator complex subunit 15 DUF1637 PF07847.7 GAM22148.1 - 7.9e-36 123.3 0.1 9.6e-36 123.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Abhydro_lipase PF04083.11 GAM22149.1 - 2.5e-21 74.7 0.0 4.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAM22149.1 - 5e-10 39.3 0.2 7.4e-10 38.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM22149.1 - 9.6e-07 28.9 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM22149.1 - 4.1e-05 23.3 0.0 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peripla_BP_6 PF13458.1 GAM22149.1 - 0.033 13.5 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Aldo_ket_red PF00248.16 GAM22150.1 - 2.7e-74 249.5 0.0 3e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acetyltransf_3 PF13302.1 GAM22151.1 - 1.3e-20 73.9 0.0 1.5e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM22151.1 - 2.2e-07 30.8 0.0 1.6e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM22151.1 - 0.0018 18.2 0.0 0.0046 16.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM22151.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM22151.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein THF_DHG_CYH_C PF02882.14 GAM22152.1 - 5.5e-16 58.0 1.3 8.5e-14 50.9 0.9 3.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 GAM22152.1 - 4.9e-15 55.5 0.0 9.7e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain PHB_acc PF05233.8 GAM22152.1 - 1.4 8.6 5.5 0.22 11.2 0.2 2.2 3 0 0 3 3 3 0 PHB accumulation regulatory domain SRF-TF PF00319.13 GAM22153.1 - 5.3e-16 57.5 0.2 1.8e-15 55.9 0.2 1.9 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Caudo_TAP PF02413.12 GAM22154.1 - 0.01 16.0 1.7 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein TraA PF05513.6 GAM22154.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 TraA ABC_tran PF00005.22 GAM22155.1 - 7.1e-45 152.6 0.0 5.9e-21 75.2 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 GAM22155.1 - 4.4e-21 74.5 1.5 1e-19 70.1 0.6 2.9 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 GAM22155.1 - 1.9e-19 70.7 1.5 0.00018 21.5 0.2 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 GAM22155.1 - 1.1e-08 34.5 0.2 0.039 13.1 0.0 4.5 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM22155.1 - 6.1e-08 32.8 0.1 0.012 15.6 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.1 GAM22155.1 - 1.2e-07 32.3 3.9 0.0058 16.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 GAM22155.1 - 1.2e-07 31.1 0.0 0.0027 17.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM22155.1 - 3.9e-07 29.4 0.0 0.00061 19.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM22155.1 - 7.8e-07 29.9 0.0 0.0065 17.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 GAM22155.1 - 2.1e-06 27.4 0.0 0.0062 16.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Miro PF08477.8 GAM22155.1 - 3.1e-06 27.6 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 GAM22155.1 - 3.2e-06 27.2 0.0 0.0044 17.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 GAM22155.1 - 2.5e-05 24.1 0.0 0.37 10.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 GAM22155.1 - 3.1e-05 24.1 0.0 0.039 14.1 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 GAM22155.1 - 7.3e-05 22.9 0.0 0.0061 16.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAM22155.1 - 9.7e-05 22.6 0.0 0.56 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 GAM22155.1 - 0.00019 21.3 0.0 0.027 14.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 GAM22155.1 - 0.00021 21.1 0.2 0.23 11.2 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function DUF87 AAA_33 PF13671.1 GAM22155.1 - 0.00037 20.4 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM22155.1 - 0.00041 19.7 0.0 0.25 10.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM22155.1 - 0.00046 19.7 0.4 0.046 13.1 0.0 2.7 3 0 0 3 3 2 1 AAA-like domain AAA_28 PF13521.1 GAM22155.1 - 0.0011 18.9 0.0 1.9 8.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 GAM22155.1 - 0.0016 18.2 0.5 1.5 8.4 0.0 2.6 3 0 0 3 3 2 2 Archaeal ATPase MobB PF03205.9 GAM22155.1 - 0.0025 17.5 0.0 0.032 13.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 GAM22155.1 - 0.0054 15.6 0.0 0.45 9.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.9 GAM22155.1 - 0.0056 16.4 1.1 0.24 11.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 GAM22155.1 - 0.008 16.0 0.3 0.99 9.3 0.1 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 GAM22155.1 - 0.015 14.1 0.0 4.2 6.0 0.0 2.4 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 GAM22155.1 - 0.015 15.1 0.0 7.2 6.3 0.0 3.0 2 1 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 GAM22155.1 - 0.016 14.9 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 GAM22155.1 - 0.026 14.0 0.1 10 5.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2813 PF11398.3 GAM22155.1 - 0.036 13.1 0.0 0.67 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) DAP3 PF10236.4 GAM22155.1 - 0.051 12.5 0.1 4.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 GAM22155.1 - 0.057 12.3 0.0 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 GAM22155.1 - 0.088 11.4 2.8 8.6 4.9 1.8 2.7 2 1 0 2 2 2 0 G-protein alpha subunit MarR_2 PF12802.2 GAM22155.1 - 0.12 12.0 0.0 0.4 10.3 0.0 1.9 1 0 0 1 1 1 0 MarR family RVT_1 PF00078.22 GAM22156.1 - 1.4e-36 125.8 0.0 2.3e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fork_head PF00250.13 GAM22156.1 - 0.0022 17.9 0.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Fork head domain Mucin PF01456.12 GAM22157.1 - 0.0085 15.8 31.7 0.014 15.1 22.0 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 GAM22157.1 - 1.1 7.1 24.4 1.5 6.6 16.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1510 PF07423.6 GAM22159.1 - 0.03 13.7 0.2 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 GAM22159.1 - 0.41 10.4 3.0 0.49 10.2 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zn-ribbon_8 PF09723.5 GAM22159.1 - 9.4 6.2 17.0 4.5 7.3 0.2 3.4 3 0 0 3 3 3 0 Zinc ribbon domain SIN1 PF05422.7 GAM22160.1 - 1.5e-11 43.5 0.3 1.5e-11 43.5 0.2 2.8 2 2 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 GAM22160.1 - 0.0023 17.6 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain MARVEL PF01284.18 GAM22162.1 - 0.078 12.7 3.7 0.084 12.6 2.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain Orbi_NS3 PF01616.11 GAM22162.1 - 9.3 5.1 7.3 12 4.8 5.1 1.3 1 1 0 1 1 1 0 Orbivirus NS3 Methyltransf_2 PF00891.13 GAM22163.1 - 2.1e-46 158.1 0.0 3e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM22163.1 - 5.7e-06 26.1 0.1 2.2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain HTH_Tnp_1_2 PF13022.1 GAM22163.1 - 0.016 15.0 0.1 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase Methyltransf_12 PF08242.7 GAM22163.1 - 0.057 13.9 0.0 0.17 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain HTH_28 PF13518.1 GAM22163.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 GAM22163.1 - 0.21 11.1 0.4 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Beach PF02138.13 GAM22164.1 - 6e-108 360.3 0.9 1.1e-107 359.5 0.3 1.7 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.27 GAM22164.1 - 9.9e-33 110.8 14.0 5.4e-09 35.5 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat PH_BEACH PF14844.1 GAM22164.1 - 2.8e-21 75.3 1.1 1.7e-19 69.6 0.4 2.7 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH GRAM PF02893.15 GAM22164.1 - 0.00025 20.4 0.1 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 GRAM domain BBS2_Mid PF14783.1 GAM22164.1 - 0.0012 18.5 0.2 0.35 10.6 0.0 4.1 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region AAA_16 PF13191.1 GAM22165.1 - 3.4e-05 23.9 0.0 0.00023 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 GAM22165.1 - 0.0013 18.5 0.0 0.0093 15.7 0.0 2.6 2 1 0 2 2 2 1 Dynamin family DUF2356 PF10189.4 GAM22165.1 - 0.0088 15.1 0.1 0.021 13.9 0.0 1.6 1 0 0 1 1 1 1 Conserved protein (DUF2356) MMR_HSR1 PF01926.18 GAM22165.1 - 0.073 13.0 0.0 0.36 10.7 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-C2H2_2 PF12756.2 GAM22166.1 - 2.7e-39 133.3 14.8 2.8e-21 75.5 1.4 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 GAM22166.1 - 4.1e-08 33.0 15.1 0.094 13.0 0.2 5.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 GAM22166.1 - 1.5e-05 24.9 16.0 0.00048 20.1 3.0 4.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 GAM22166.1 - 0.00015 21.9 21.4 0.028 14.7 1.9 5.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-met PF12874.2 GAM22166.1 - 0.00052 20.1 3.8 0.00052 20.1 2.7 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type PAS_4 PF08448.5 GAM22166.1 - 0.024 14.6 0.0 0.067 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold PyrI_C PF02748.10 GAM22166.1 - 0.26 10.7 5.3 6.7 6.2 0.0 3.8 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4187 PF13821.1 GAM22166.1 - 0.83 9.2 13.8 1.1 8.9 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4187) zf-Di19 PF05605.7 GAM22166.1 - 3.3 7.9 24.3 0.61 10.2 0.1 5.3 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding A2L_zn_ribbon PF08792.5 GAM22166.1 - 9.7 5.7 10.1 9.3 5.8 0.1 3.6 3 0 0 3 3 3 0 A2L zinc ribbon domain Myb_DNA-bind_6 PF13921.1 GAM22168.1 - 0.023 14.8 0.1 0.075 13.1 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM22168.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Methyltransf_2 PF00891.13 GAM22170.1 - 2.4e-51 174.2 0.0 4e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 GAM22170.1 - 0.00049 19.8 0.0 0.0012 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM22170.1 - 0.0018 18.8 0.0 0.0056 17.2 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain HTH_20 PF12840.2 GAM22170.1 - 0.049 13.4 0.1 0.09 12.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_12 PF08242.7 GAM22170.1 - 0.054 13.9 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Macro PF01661.16 GAM22171.1 - 4.2e-32 110.5 0.1 1e-31 109.2 0.1 1.7 1 0 0 1 1 1 1 Macro domain DUF2477 PF10631.4 GAM22171.1 - 0.28 11.4 23.1 0.74 10.0 16.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Amidinotransf PF02274.12 GAM22172.1 - 1.1e-28 100.0 0.0 1.5e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase SNF2_N PF00176.18 GAM22173.1 - 1.9e-65 220.6 3.9 1.9e-65 220.6 2.7 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad60-SLD PF11976.3 GAM22173.1 - 5.8e-27 93.1 5.1 8.5e-06 25.3 0.0 6.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.26 GAM22173.1 - 8.2e-15 54.4 1.5 1e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 GAM22173.1 - 6.1e-07 29.0 0.1 2.9e-06 26.8 0.1 2.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_22 PF13401.1 GAM22173.1 - 0.0041 17.2 0.3 0.4 10.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain RRM_1 PF00076.17 GAM22174.1 - 4.2e-38 128.8 0.3 1.3e-13 50.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22174.1 - 5.6e-32 109.5 0.5 7.6e-12 45.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22174.1 - 1.7e-14 53.4 0.1 7.6e-06 25.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM22174.1 - 0.0036 17.0 0.0 0.019 14.7 0.0 2.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif C1_1 PF00130.17 GAM22175.1 - 2.7e-12 46.2 23.3 2.5e-06 27.0 3.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FdtA PF05523.6 GAM22175.1 - 0.03 13.8 0.7 0.078 12.4 0.5 1.6 1 0 0 1 1 1 0 WxcM-like, C-terminal BLOC1_2 PF10046.4 GAM22175.1 - 0.082 13.0 1.4 0.27 11.3 0.2 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PHD_2 PF13831.1 GAM22175.1 - 0.13 11.6 5.1 0.57 9.5 0.2 2.6 2 0 0 2 2 2 0 PHD-finger PHD PF00628.24 GAM22175.1 - 4.3 7.1 16.1 3.1 7.5 3.2 2.5 2 0 0 2 2 2 0 PHD-finger Lipase_3 PF01764.20 GAM22176.1 - 9e-38 129.0 0.0 1.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM22176.1 - 0.0045 16.3 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAM22176.1 - 0.0099 15.6 0.0 0.017 14.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM22176.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 GAM22176.1 - 0.079 12.8 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 GAM22176.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase SET_assoc PF11767.3 GAM22176.1 - 0.093 12.0 0.1 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Myb_DNA-bind_6 PF13921.1 GAM22177.1 - 9.8e-05 22.3 0.0 0.00029 20.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 GAM22177.1 - 0.021 14.7 0.0 0.021 14.7 0.0 2.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM22177.1 - 0.051 13.6 0.1 0.18 11.8 0.1 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Metallophos PF00149.23 GAM22178.1 - 1.6e-15 57.0 1.1 2.4e-15 56.4 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FNIP PF05725.7 GAM22179.1 - 2.6e-54 180.9 10.7 9.8e-16 57.4 0.0 8.1 6 3 3 9 9 9 7 FNIP Repeat DUF1769 PF08588.5 GAM22179.1 - 6.8e-06 25.9 0.8 1.8 8.5 0.0 5.5 2 1 4 6 6 6 2 Protein of unknown function (DUF1769) PGAMP PF07644.6 GAM22179.1 - 0.078 12.7 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Planctomycete PGAMP IBN_N PF03810.14 GAM22180.1 - 6.4e-11 42.0 0.3 6.4e-11 42.0 0.2 3.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT PF02985.17 GAM22180.1 - 4.5e-05 23.1 0.1 0.11 12.6 0.0 3.5 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.7 GAM22180.1 - 0.00052 19.9 0.3 0.0064 16.4 0.0 3.1 2 1 1 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 GAM22180.1 - 0.0027 17.9 0.4 0.031 14.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 GAM22180.1 - 0.087 13.3 3.8 40 4.8 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat SDA1 PF05285.7 GAM22180.1 - 7.4 5.7 13.2 12 5.0 9.1 1.3 1 0 0 1 1 1 0 SDA1 DUF4064 PF13273.1 GAM22181.1 - 0.17 12.0 3.1 11 6.1 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FNIP PF05725.7 GAM22185.1 - 2.1e-23 81.9 5.5 4e-07 29.8 0.1 5.6 2 2 1 5 5 5 5 FNIP Repeat Exo_endo_phos PF03372.18 GAM22186.1 - 2.7e-05 24.2 0.3 3.6e-05 23.8 0.2 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAM22186.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF605 PF04652.11 GAM22187.1 - 0.0066 15.8 5.6 0.0081 15.6 3.9 1.1 1 0 0 1 1 1 1 Vta1 like SMN PF06003.7 GAM22187.1 - 0.16 11.0 4.0 0.25 10.4 2.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Nop14 PF04147.7 GAM22188.1 - 0.00091 17.2 23.6 0.00099 17.1 16.4 1.2 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 GAM22188.1 - 2.3 7.1 21.9 3.7 6.5 15.2 1.3 1 0 0 1 1 1 0 BUD22 DNA_pol_B_2 PF03175.8 GAM22189.1 - 0.00014 20.7 0.2 0.00022 20.0 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral SBP_bac_1 PF01547.20 GAM22189.1 - 0.044 13.5 0.1 0.066 12.9 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein DUF4296 PF14129.1 GAM22190.1 - 0.07 13.2 0.1 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) Alg6_Alg8 PF03155.10 GAM22191.1 - 1.1e-111 373.9 19.5 2.6e-111 372.7 13.5 1.5 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ThiF PF00899.16 GAM22192.1 - 9.4e-39 132.3 0.1 2.1e-38 131.2 0.1 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 GAM22192.1 - 1.4e-27 95.0 0.3 3.7e-27 93.6 0.2 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 GAM22192.1 - 8.1e-23 80.3 1.0 2.1e-22 78.9 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 GAM22192.1 - 1.3e-20 72.5 1.2 2.4e-20 71.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 GAM22192.1 - 2.1e-05 24.6 0.0 6.7e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 GAM22192.1 - 0.00012 22.2 0.0 0.00034 20.8 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 GAM22192.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.10 GAM22192.1 - 0.038 12.8 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 GAM22192.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rep_fac-A_C PF08646.5 GAM22193.1 - 1e-06 28.5 0.1 2.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor-A C terminal domain POT1 PF02765.12 GAM22193.1 - 6.8e-06 26.0 0.0 2.4e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 GAM22193.1 - 0.049 13.5 0.0 4.2 7.2 0.0 3.2 3 1 0 3 3 3 0 OB-fold nucleic acid binding domain Herpes_capsid PF06112.6 GAM22194.1 - 0.0073 16.3 5.8 0.0073 16.3 4.0 2.0 1 1 1 2 2 2 1 Gammaherpesvirus capsid protein Mito_fiss_reg PF05308.6 GAM22194.1 - 0.023 14.0 1.6 0.023 14.0 1.1 4.2 2 1 3 5 5 5 0 Mitochondrial fission regulator FlxA PF14282.1 GAM22194.1 - 0.26 11.2 0.1 0.26 11.2 0.1 3.1 3 0 0 3 3 3 0 FlxA-like protein Methyltransf_31 PF13847.1 GAM22196.1 - 1.1e-23 83.5 0.0 1.2e-23 83.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM22196.1 - 4.4e-21 75.1 0.0 7.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM22196.1 - 2.2e-15 56.4 0.0 3.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM22196.1 - 2.3e-13 50.3 0.0 3.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM22196.1 - 7.4e-12 45.6 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM22196.1 - 4.5e-10 39.4 0.0 6.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM22196.1 - 5.7e-10 39.7 0.0 9.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 GAM22196.1 - 4.5e-07 29.4 0.0 6.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 GAM22196.1 - 2.9e-05 23.7 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.11 GAM22196.1 - 0.0011 17.8 0.0 0.0019 17.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_26 PF13659.1 GAM22196.1 - 0.0012 18.8 0.0 0.0032 17.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM22196.1 - 0.0016 17.4 0.0 0.0033 16.4 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 GAM22196.1 - 0.0058 16.3 0.0 0.014 15.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM22196.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 GAM22196.1 - 0.049 12.6 0.1 0.051 12.6 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase RRM_1 PF00076.17 GAM22197.1 - 3.5e-18 64.9 0.0 5.3e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22197.1 - 2.1e-14 53.1 0.0 3.6e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22197.1 - 9.9e-12 44.6 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Amino_oxidase PF01593.19 GAM22198.1 - 1.8e-44 152.5 0.0 4.4e-37 128.2 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM22198.1 - 3.4e-09 36.5 0.1 8.1e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM22198.1 - 1.3e-05 24.3 0.0 3.3e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM22198.1 - 2.5e-05 22.9 0.1 5.5e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 GAM22198.1 - 8e-05 21.8 0.2 0.0002 20.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAM22198.1 - 0.0014 17.6 0.1 0.0024 16.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 GAM22198.1 - 0.0022 17.8 0.0 0.0098 15.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM22198.1 - 0.003 16.6 0.4 0.0053 15.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM22198.1 - 0.0041 17.4 0.1 0.81 10.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM22198.1 - 0.0047 15.9 0.0 0.025 13.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 GAM22198.1 - 0.019 15.0 0.2 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM22198.1 - 0.048 12.7 0.0 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 GAM22198.1 - 0.052 12.4 0.1 0.12 11.2 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.20 GAM22199.1 - 1.1e-69 234.4 0.3 1.4e-69 234.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22199.1 - 3.5e-53 180.3 0.2 4.6e-53 179.9 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22199.1 - 3e-08 33.0 0.0 6.5e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like CLAMP PF14769.1 GAM22199.1 - 0.0047 17.0 0.5 0.012 15.7 0.3 1.6 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 RIO1 PF01163.17 GAM22199.1 - 0.011 15.0 0.2 0.02 14.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 GAM22199.1 - 0.052 12.6 0.3 0.1 11.6 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM22199.1 - 0.062 13.0 0.0 2.5 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD_binding_4 PF01565.18 GAM22201.1 - 1.3e-30 105.7 0.0 2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 GAM22201.1 - 3.6e-17 61.9 4.3 1e-16 60.5 3.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.2 GAM22202.1 - 1.7e-78 259.0 23.0 4.8e-20 71.6 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM22202.1 - 3e-45 149.8 9.4 8e-09 34.8 0.1 7.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 GAM22202.1 - 8.2e-39 127.7 5.0 9.3e-07 28.5 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 GAM22202.1 - 1.3e-37 127.4 8.8 3.9e-11 43.1 0.0 4.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22202.1 - 4.2e-32 109.4 12.4 2.2e-09 37.2 0.1 5.8 2 1 5 7 7 6 5 Ankyrin repeats (many copies) TPR_11 PF13414.1 GAM22202.1 - 8.7e-13 47.7 12.1 3.2e-08 33.0 1.9 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAM22202.1 - 2.6e-07 30.0 8.0 0.0017 18.1 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM22202.1 - 7.4e-05 22.6 1.2 0.013 15.4 1.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM22202.1 - 0.0002 20.8 9.2 0.0084 15.6 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM22202.1 - 0.0036 16.9 2.0 1.3 8.9 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM22202.1 - 0.0067 17.0 3.0 0.3 11.8 0.7 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat Gas_vesicle_C PF01304.12 GAM22202.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain TPR_17 PF13431.1 GAM22202.1 - 0.033 14.3 0.4 0.31 11.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec7 PF01369.15 GAM22202.1 - 0.74 9.4 4.4 1.1 8.8 1.1 2.2 2 0 0 2 2 2 0 Sec7 domain C2 PF00168.25 GAM22204.1 - 6.3e-07 29.1 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain GNT-I PF03071.10 GAM22205.1 - 5.8e-06 25.1 0.1 7.9e-06 24.6 0.1 1.3 1 0 0 1 1 1 1 GNT-I family Glyco_transf_18 PF15024.1 GAM22205.1 - 0.044 12.1 1.4 0.057 11.7 0.9 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 CH PF00307.26 GAM22206.1 - 1.9e-43 146.9 2.9 2.7e-23 82.0 0.0 4.6 4 0 0 4 4 4 3 Calponin homology (CH) domain Spectrin PF00435.16 GAM22206.1 - 3.2e-32 110.9 27.5 5.3e-12 45.9 0.4 4.6 4 0 0 4 4 4 4 Spectrin repeat CAMSAP_CH PF11971.3 GAM22206.1 - 1.1e-13 50.6 1.6 4e-10 39.2 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain EFhand_Ca_insen PF08726.5 GAM22206.1 - 2e-11 43.6 0.0 9.9e-11 41.4 0.0 2.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_7 PF13499.1 GAM22206.1 - 1e-05 25.5 0.4 5.4e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM22206.1 - 0.00053 19.6 0.1 0.0054 16.5 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 GAM22206.1 - 0.01 15.1 0.1 0.47 9.8 0.0 2.8 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 GAM22206.1 - 0.014 14.9 0.3 1.8 8.2 0.0 3.0 1 1 1 2 2 2 0 EF-hand domain pair RAI1 PF08652.6 GAM22206.1 - 0.21 11.4 2.7 2.1 8.1 0.3 2.6 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease DUF4375 PF14300.1 GAM22206.1 - 0.65 9.9 7.9 0.79 9.7 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4375) LSM PF01423.17 GAM22208.1 - 2.7e-14 52.4 0.5 3.9e-14 51.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM22208.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Feld-I_B PF09252.5 GAM22208.1 - 0.047 13.5 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain CLU PF13236.1 GAM22209.1 - 2e-51 174.5 0.0 4.2e-51 173.4 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM22209.1 - 1.1e-10 41.6 0.0 1.1e-10 41.6 0.0 3.0 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 DUF1349 PF07081.6 GAM22210.1 - 2.5e-60 202.9 0.3 2.9e-60 202.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Peptidase_M48 PF01435.13 GAM22211.1 - 2.5e-45 154.7 0.0 4.3e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 GAM22211.1 - 0.013 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_M56 PF05569.6 GAM22211.1 - 0.66 8.8 7.2 0.2 10.5 0.2 2.5 3 0 0 3 3 3 0 BlaR1 peptidase M56 FA_desaturase PF00487.19 GAM22211.1 - 2.8 7.3 9.5 0.82 9.0 3.0 2.4 2 1 0 2 2 2 0 Fatty acid desaturase DUF3980 PF13140.1 GAM22211.1 - 9 6.6 10.4 0.37 11.0 2.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) Ras PF00071.17 GAM22212.1 - 3.3e-52 176.1 0.3 3.8e-52 175.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM22212.1 - 5.4e-18 65.6 0.0 8.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM22212.1 - 3.5e-10 39.4 0.3 4.1e-10 39.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM22212.1 - 6.7e-05 22.3 0.3 0.0001 21.7 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM22212.1 - 0.00091 19.1 0.1 0.0013 18.6 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3568 PF12092.3 GAM22212.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) RRM_1 PF00076.17 GAM22213.1 - 2.3e-69 228.9 2.0 1.5e-18 66.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22213.1 - 1.5e-52 175.4 0.3 6.6e-12 45.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22213.1 - 1.9e-36 123.6 0.1 1.7e-09 37.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAM22213.1 - 3.9e-10 39.2 0.2 1.1e-09 37.7 0.1 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 GAM22213.1 - 4e-06 26.6 2.5 0.041 13.7 0.0 4.1 3 1 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 GAM22213.1 - 0.00044 19.9 1.3 0.55 10.0 0.1 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 GAM22213.1 - 0.00052 19.7 0.4 1 9.1 0.0 3.4 2 1 1 3 3 3 2 Limkain b1 TSA PF03249.8 GAM22213.1 - 1.4 7.3 8.0 2.5 6.5 5.6 1.3 1 0 0 1 1 1 0 Type specific antigen Glycos_transf_4 PF00953.16 GAM22214.1 - 1.1e-34 119.5 14.4 1.1e-34 119.5 10.0 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 Myosin_head PF00063.16 GAM22215.1 - 2.6e-258 858.6 0.0 3.8e-258 858.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM22215.1 - 1e-54 184.8 1.7 3.7e-54 183.0 1.7 1.6 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 GAM22215.1 - 3.6e-17 61.4 0.2 7.4e-17 60.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM22215.1 - 6.9e-17 60.7 0.1 1.4e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM22215.1 - 1.2e-12 47.0 0.1 2.4e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 GAM22215.1 - 0.00095 19.3 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM22215.1 - 0.01 16.6 0.5 0.13 13.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain IQ PF00612.22 GAM22215.1 - 0.019 14.5 0.1 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Zeta_toxin PF06414.7 GAM22215.1 - 0.023 13.8 1.2 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 GAM22215.1 - 0.051 13.0 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 GAM22215.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 GAM22215.1 - 0.11 12.4 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SH3_4 PF06347.8 GAM22215.1 - 0.14 11.7 1.9 0.15 11.6 0.3 1.8 2 0 0 2 2 2 0 Bacterial SH3 domain ABC_tran PF00005.22 GAM22215.1 - 0.7 10.1 3.2 0.78 10.0 0.2 2.6 2 2 0 2 2 2 0 ABC transporter zf-ribbon_3 PF13248.1 GAM22216.1 - 7e-05 21.9 5.8 0.0045 16.1 1.7 2.7 2 0 0 2 2 2 2 zinc-ribbon domain DZR PF12773.2 GAM22216.1 - 0.0024 17.6 10.0 0.036 13.8 6.9 2.3 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAM22216.1 - 0.03 13.7 10.6 0.37 10.3 3.9 3.1 2 1 1 3 3 3 0 zinc-ribbon domain C1_1 PF00130.17 GAM22216.1 - 0.063 13.0 4.8 3.4 7.4 0.4 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 GAM22216.1 - 0.11 12.5 0.6 0.11 12.5 0.4 2.8 2 2 0 2 2 2 0 LIM domain A2L_zn_ribbon PF08792.5 GAM22216.1 - 0.54 9.7 4.3 20 4.7 0.1 3.5 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF4451 PF14616.1 GAM22216.1 - 0.74 9.5 4.7 1.1 9.0 3.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) DnaJ_CXXCXGXG PF00684.14 GAM22216.1 - 0.74 9.9 4.3 0.39 10.7 0.3 2.3 2 1 0 2 2 2 0 DnaJ central domain Prok-RING_1 PF14446.1 GAM22216.1 - 4.1 7.2 7.2 2.3 8.0 0.5 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_3 PF14369.1 GAM22216.1 - 6.7 6.7 10.6 17 5.5 0.1 3.3 2 1 1 3 3 3 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 GAM22216.1 - 7.1 6.5 9.3 7.2 6.5 0.7 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 GAM22216.1 - 8.8 6.6 9.2 11 6.3 0.3 2.9 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain RabGAP-TBC PF00566.13 GAM22217.1 - 4.2e-45 153.8 8.2 4.2e-45 153.8 5.7 3.9 4 1 0 4 4 4 1 Rab-GTPase-TBC domain Pox_A51 PF04948.8 GAM22217.1 - 0.018 13.7 1.8 0.033 12.8 1.2 1.3 1 0 0 1 1 1 0 Poxvirus A51 protein DUF342 PF03961.8 GAM22217.1 - 0.6 8.4 7.2 0.11 10.9 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) LOH1CR12 PF10158.4 GAM22217.1 - 1.1 9.0 15.2 0.022 14.5 4.3 2.8 2 1 1 3 3 3 0 Tumour suppressor protein DUF948 PF06103.6 GAM22217.1 - 3.9 7.3 5.4 23 4.9 3.7 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FYVE PF01363.16 GAM22218.1 - 0.00011 22.0 7.0 0.00011 21.9 3.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 GAM22218.1 - 0.012 15.2 2.1 0.012 15.2 1.5 2.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Bac_DnaA_C PF08299.6 GAM22218.1 - 0.055 13.3 0.1 0.18 11.7 0.1 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein helix-turn-helix PH_2 PF08458.5 GAM22218.1 - 0.095 12.6 0.1 2.5 8.0 0.0 2.7 3 0 0 3 3 3 0 Plant pleckstrin homology-like region DZR PF12773.2 GAM22218.1 - 0.24 11.2 11.6 1.7 8.5 5.2 2.8 2 1 1 3 3 3 0 Double zinc ribbon FYVE_2 PF02318.11 GAM22218.1 - 0.62 9.9 13.1 0.14 12.0 5.1 2.6 2 1 0 2 2 2 0 FYVE-type zinc finger UQ_con PF00179.21 GAM22219.1 - 1.2e-26 92.8 0.0 1.2e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 GAM22219.1 - 0.0097 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 UEV domain Filo_glycop PF01611.11 GAM22219.1 - 0.34 9.6 6.9 0.041 12.6 1.0 2.0 2 0 0 2 2 2 0 Filovirus glycoprotein Tho2 PF11262.3 GAM22222.1 - 3e-66 223.4 5.8 3e-66 223.4 4.1 3.6 3 1 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 GAM22222.1 - 9.7e-22 76.5 0.0 3e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Cyclin PF08613.6 GAM22223.1 - 2.7e-32 112.2 0.2 2.7e-32 112.2 0.1 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM22223.1 - 9.3e-10 38.1 0.0 1.6e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DER1 PF04511.10 GAM22223.1 - 0.01 15.3 0.3 0.014 14.9 0.2 1.2 1 0 0 1 1 1 0 Der1-like family DUF2217 PF10265.4 GAM22223.1 - 0.93 8.1 3.8 1.2 7.7 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) IL13 PF03487.8 GAM22224.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Interleukin-13 DUF4131 PF13567.1 GAM22224.1 - 0.33 10.3 1.8 0.5 9.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 GAM22224.1 - 0.37 10.7 6.3 0.43 10.5 1.0 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Patched PF02460.13 GAM22224.1 - 1.2 6.9 6.3 0.81 7.5 3.6 1.3 1 1 0 1 1 1 0 Patched family DUF308 PF03729.8 GAM22224.1 - 4.6 7.3 10.5 7 6.7 1.4 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Glycos_transf_1 PF00534.15 GAM22225.1 - 9.6e-36 122.7 0.0 1.5e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM22225.1 - 2.6e-11 43.9 0.0 4.2e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 GAM22225.1 - 2.8e-10 40.2 0.4 6e-10 39.1 0.1 1.7 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAM22225.1 - 6.4e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAM22225.1 - 2e-05 24.7 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 LRR_8 PF13855.1 GAM22226.1 - 2.2e-07 30.5 16.3 1.2e-06 28.1 3.6 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 GAM22226.1 - 1.2e-06 28.0 10.4 7.7e-06 25.4 1.0 4.0 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 GAM22226.1 - 2.2e-05 24.0 0.6 2.2e-05 24.0 0.4 1.8 2 1 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 GAM22226.1 - 0.0016 18.2 10.7 4 7.8 0.1 5.1 3 1 1 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.28 GAM22226.1 - 0.085 12.9 16.3 1.8 8.9 0.0 5.0 4 1 1 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 GAM22226.1 - 0.11 12.8 11.5 5 7.7 0.1 4.7 3 1 1 4 4 4 0 Leucine rich repeat Mpv17_PMP22 PF04117.7 GAM22227.1 - 2.9e-22 78.0 0.2 5.1e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF515 PF04415.7 GAM22228.1 - 1.1 7.4 11.0 2.7 6.1 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2616 PF11077.3 GAM22229.1 - 0.073 12.5 1.1 0.085 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) DUF2935 PF11155.3 GAM22231.1 - 0.01 15.8 2.1 0.018 15.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) EF-hand_2 PF09068.6 GAM22231.1 - 0.017 15.1 0.3 0.04 14.0 0.2 1.6 1 0 0 1 1 1 0 EF hand DUF948 PF06103.6 GAM22231.1 - 0.081 12.7 3.9 3.3 7.6 2.3 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Med15_fungi PF05397.7 GAM22231.1 - 0.1 12.5 2.9 0.082 12.8 0.4 2.1 2 1 1 3 3 3 0 Mediator complex subunit 15 DDE_3 PF13358.1 GAM22232.1 - 2.1e-08 34.0 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RSS_P20 PF11757.3 GAM22232.1 - 0.068 13.3 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like BetaGal_dom4_5 PF13364.1 GAM22233.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Astro_capsid PF03115.9 GAM22233.1 - 2.6 6.1 9.3 3.1 5.9 6.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Beta_helix PF13229.1 GAM22234.1 - 0.14 11.8 2.8 0.19 11.4 1.9 1.2 1 0 0 1 1 1 0 Right handed beta helix region PQ-loop PF04193.9 GAM22236.1 - 6.3e-20 70.4 13.8 1.7e-16 59.4 0.2 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 GAM22236.1 - 0.0062 17.0 10.4 0.025 15.0 7.0 2.1 1 1 0 1 1 1 1 ER lumen protein retaining receptor Gelsolin PF00626.17 GAM22236.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Gelsolin repeat AzlD PF05437.7 GAM22236.1 - 0.077 12.9 1.0 0.46 10.4 0.1 2.2 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) MtN3_slv PF03083.11 GAM22236.1 - 0.3 10.9 10.2 0.2 11.5 1.8 2.8 1 1 2 3 3 3 0 Sugar efflux transporter for intercellular exchange BolA PF01722.13 GAM22237.1 - 1.3e-17 63.4 0.0 1.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DUF3124 PF11322.3 GAM22237.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) zf-C2H2_2 PF12756.2 GAM22238.1 - 1.9e-34 117.8 12.8 2.7e-28 98.0 1.9 3.0 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 GAM22238.1 - 3.3e-09 36.6 5.5 2.3e-07 30.7 1.5 3.9 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM22238.1 - 1.6e-08 34.4 0.8 1.6e-08 34.4 0.5 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAM22238.1 - 2 8.4 6.4 0.68 9.9 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 GAM22238.1 - 2.9 8.4 15.9 1.3 9.5 0.2 4.5 4 1 1 5 5 5 0 C2H2-type zinc finger zf-LYAR PF08790.6 GAM22238.1 - 6.8 6.4 8.4 1.2 8.8 0.2 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Ribosomal_S8e PF01201.17 GAM22239.1 - 2.2e-35 121.6 7.2 1.1e-33 116.2 5.0 2.5 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 GAM22239.1 - 0.017 14.8 0.9 0.29 10.8 0.1 2.2 2 0 0 2 2 2 0 Homeo-prospero domain Alpha-amylase PF00128.19 GAM22240.1 - 4.1e-22 78.9 0.0 3.9e-21 75.7 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Acyltransferase PF01553.16 GAM22241.1 - 3.2e-21 75.1 0.0 5.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ATP-synt_ab PF00006.20 GAM22242.1 - 3.7e-62 209.6 0.0 5.8e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM22242.1 - 6.5e-24 84.5 0.4 6.5e-24 84.5 0.3 2.3 3 0 0 3 3 3 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM22242.1 - 1.6e-19 69.8 1.5 2.5e-18 66.0 1.0 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain MobB PF03205.9 GAM22242.1 - 0.013 15.1 0.6 1.3 8.7 0.1 3.1 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 GAM22242.1 - 0.019 15.0 0.0 0.076 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAM22242.1 - 0.02 14.0 0.1 0.04 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM22242.1 - 0.021 14.2 0.6 0.16 11.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 GAM22242.1 - 0.027 14.6 0.6 0.36 11.0 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM22242.1 - 0.028 14.4 0.3 0.11 12.4 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 GAM22242.1 - 0.03 13.9 0.1 0.083 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain VitK2_biosynth PF02621.9 GAM22242.1 - 0.03 13.5 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Menaquinone biosynthesis RNA_helicase PF00910.17 GAM22242.1 - 0.041 14.0 0.9 0.37 10.9 0.0 3.0 5 0 0 5 5 3 0 RNA helicase NB-ARC PF00931.17 GAM22242.1 - 0.056 12.2 1.5 0.1 11.3 0.2 1.9 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 GAM22242.1 - 0.063 12.3 2.6 0.063 12.3 0.2 2.2 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 GAM22242.1 - 0.087 12.5 2.5 0.21 11.2 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 GAM22242.1 - 0.11 12.8 2.6 0.61 10.3 0.1 2.8 3 0 0 3 3 3 0 ABC transporter HORMA PF02301.13 GAM22243.1 - 2.3e-05 23.9 0.0 0.00026 20.5 0.0 2.1 1 1 0 1 1 1 1 HORMA domain DUF605 PF04652.11 GAM22243.1 - 0.16 11.3 8.9 0.26 10.6 6.2 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 GAM22243.1 - 0.93 7.6 15.5 1.2 7.2 10.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PSCyt3 PF07627.6 GAM22243.1 - 0.98 9.3 3.5 0.92 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) FMN_red PF03358.10 GAM22244.1 - 5.7e-28 97.3 0.0 8.6e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM22244.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Ank_2 PF12796.2 GAM22245.1 - 1.7e-51 172.5 19.2 2.4e-12 46.9 0.2 8.8 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22245.1 - 2.4e-42 142.5 19.2 5.6e-08 33.0 0.1 11.4 5 3 9 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22245.1 - 2.3e-38 129.3 24.2 0.0037 17.4 0.0 16.0 3 2 14 18 18 18 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22245.1 - 1.1e-29 99.5 20.3 0.018 15.2 0.0 16.6 8 4 10 18 18 18 7 Ankyrin repeat Ank PF00023.25 GAM22245.1 - 1.6e-24 84.4 17.9 0.052 13.3 0.0 15.7 15 4 3 18 18 18 6 Ankyrin repeat DUF2493 PF10686.4 GAM22245.1 - 1.6e-05 24.3 7.9 2.7 7.5 0.3 6.9 4 2 5 9 9 9 2 Protein of unknown function (DUF2493) Rbsn PF11464.3 GAM22245.1 - 0.0078 15.7 6.4 43 3.7 0.0 7.7 10 0 0 10 10 10 0 Rabenosyn Rab binding domain DUF1906 PF08924.6 GAM22245.1 - 0.04 13.7 0.0 3 7.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1906) Peptidase_C12 PF01088.16 GAM22246.1 - 8.1e-72 240.8 0.1 1e-71 240.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PPR PF01535.15 GAM22248.1 - 0.0015 18.3 0.1 4.7 7.4 0.0 3.3 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 GAM22248.1 - 0.0092 15.9 0.0 23 5.0 0.0 4.0 3 0 0 3 3 3 1 PPR repeat family TPR_14 PF13428.1 GAM22248.1 - 0.016 15.8 0.1 20 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GCFC PF07842.7 GAM22249.1 - 1.3e-55 188.7 5.2 1.3e-55 188.7 3.6 1.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 GAM22249.1 - 4.6e-11 42.7 15.4 4.6e-11 42.7 10.6 3.5 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.18 GAM22249.1 - 8.3e-08 31.9 1.3 2.3e-07 30.4 0.9 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM22249.1 - 0.0032 17.2 1.0 0.0032 17.2 0.7 3.3 2 1 1 3 3 3 1 DExH-box splicing factor binding site CN_hydrolase PF00795.17 GAM22250.1 - 3.6e-27 94.9 0.0 1.4e-26 93.0 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DUF3875 PF12991.2 GAM22250.1 - 0.06 13.0 0.0 0.58 9.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) Peptidase_S8 PF00082.17 GAM22251.1 - 2.2e-41 141.8 0.0 3.4e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family PARP PF00644.15 GAM22252.1 - 1.2e-44 152.2 0.0 2e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 GAM22252.1 - 1.7e-39 134.5 0.2 3.1e-39 133.6 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.7 GAM22252.1 - 8.5e-20 69.9 1.6 8.5e-20 69.9 1.1 2.1 2 0 0 2 2 2 1 PADR1 (NUC008) domain zf-PARP PF00645.13 GAM22252.1 - 2.9e-16 59.4 0.1 9.7e-16 57.7 0.1 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.10 GAM22252.1 - 2.2e-15 56.3 0.2 6.6e-15 54.8 0.2 1.9 1 0 0 1 1 1 1 WGR domain Toxin_49 PF15529.1 GAM22252.1 - 0.078 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Putative toxin 49 FNIP PF05725.7 GAM22253.1 - 1.6e-72 239.2 22.7 6.6e-14 51.5 0.1 7.1 5 1 4 9 9 9 8 FNIP Repeat Ank_2 PF12796.2 GAM22254.1 - 1.6e-07 31.5 7.4 0.36 11.1 0.0 7.8 6 4 2 8 8 8 4 Ankyrin repeats (3 copies) Lsm_interact PF05391.6 GAM22255.1 - 0.027 13.8 0.1 0.069 12.6 0.1 1.7 1 0 0 1 1 1 0 Lsm interaction motif Nop14 PF04147.7 GAM22255.1 - 0.23 9.3 4.8 0.24 9.2 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 GAM22255.1 - 0.81 9.4 5.1 1.2 8.8 3.5 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-C2H2 PF00096.21 GAM22255.1 - 0.89 10.0 10.5 0.13 12.6 2.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRN3 PF05327.6 GAM22255.1 - 1.2 7.1 6.3 1.5 6.8 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 GAM22255.1 - 2.8 5.8 5.4 3 5.7 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.22 GAM22256.1 - 1.5e-50 171.0 0.0 4.3e-26 91.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAM22256.1 - 9.6e-38 130.0 61.4 1.9e-19 69.8 20.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 GAM22256.1 - 6.8e-20 72.1 0.3 1.1e-06 28.8 0.0 5.4 5 0 0 5 5 5 4 AAA domain AAA_15 PF13175.1 GAM22256.1 - 1.6e-05 24.1 0.0 0.22 10.5 0.0 4.2 4 1 0 5 5 5 2 AAA ATPase domain AAA_29 PF13555.1 GAM22256.1 - 3e-05 23.4 1.5 0.022 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 GAM22256.1 - 0.00028 20.1 0.0 3.2 6.9 0.0 3.6 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 GAM22256.1 - 0.0011 18.8 0.0 0.28 11.1 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 GAM22256.1 - 0.0068 15.8 1.6 0.97 8.8 0.1 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 GAM22256.1 - 0.034 14.4 5.6 1.3 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 GAM22256.1 - 0.057 12.6 0.1 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM22256.1 - 0.079 12.3 0.3 2.8 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Cofilin_ADF PF00241.15 GAM22257.1 - 9.8e-23 80.4 0.0 5.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein YqfD PF06898.6 GAM22257.1 - 0.035 12.7 1.1 4.5 5.8 0.1 2.9 2 1 1 3 3 3 0 Putative stage IV sporulation protein YqfD Rhomboid PF01694.17 GAM22258.1 - 9.8e-23 80.8 8.5 1.8e-22 79.9 5.9 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 GAM22258.1 - 0.021 15.1 0.1 0.057 13.7 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Halogen_Hydrol PF10112.4 GAM22258.1 - 0.28 10.5 1.3 0.43 9.9 0.1 1.9 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF702 PF05142.7 GAM22259.1 - 0.0003 20.9 9.4 0.0003 20.9 6.5 2.7 3 1 1 4 4 4 1 Domain of unknown function (DUF702) zf-DHHC PF01529.15 GAM22259.1 - 0.0016 17.8 4.9 0.0048 16.3 3.4 1.7 1 0 0 1 1 1 1 DHHC palmitoyltransferase PBP1_TM PF14812.1 GAM22259.1 - 3.4 8.0 11.6 5.2 7.4 4.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_1 PF01344.20 GAM22260.1 - 0.0034 16.9 0.4 0.026 14.0 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 GAM22260.1 - 0.11 12.7 0.3 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Kelch motif LRR_8 PF13855.1 GAM22261.1 - 2.8e-19 68.6 11.2 1.4e-10 40.7 0.2 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 GAM22261.1 - 3.3e-13 48.9 24.8 4.6e-07 29.3 1.0 4.6 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM22261.1 - 6.6e-09 34.5 18.9 0.032 14.2 0.1 7.7 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 GAM22261.1 - 4.9e-08 31.9 3.6 2.2 8.8 0.0 6.0 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 GAM22261.1 - 0.64 10.2 0.0 0.64 10.2 0.0 6.6 8 0 0 8 8 8 0 Leucine Rich repeat DUF718 PF05336.8 GAM22262.1 - 8e-25 86.6 1.5 9e-25 86.5 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) PPR_2 PF13041.1 GAM22263.1 - 0.023 14.6 0.1 3.4 7.6 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family Rgp1 PF08737.5 GAM22264.1 - 2.9e-58 197.9 11.0 1.4e-35 123.2 1.4 3.5 2 2 1 3 3 3 2 Rgp1 p450 PF00067.17 GAM22265.1 - 8.2e-93 311.4 0.3 9.2e-93 311.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 EGF_2 PF07974.8 GAM22266.1 - 0.00018 21.6 15.4 0.00043 20.3 10.7 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM22266.1 - 0.065 13.3 2.7 0.24 11.5 1.9 2.1 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.19 GAM22266.1 - 1.1 9.1 9.4 2.4 8.1 6.5 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) TIG PF01833.19 GAM22267.1 - 2.2e-60 200.5 112.0 8.9e-11 41.6 0.5 15.4 13 2 1 14 14 14 11 IPT/TIG domain DNase_II PF03265.10 GAM22267.1 - 1e-20 74.0 1.5 1.1e-13 50.8 0.7 2.4 2 0 0 2 2 2 2 Deoxyribonuclease II Nucleoplasmin PF03066.10 GAM22268.1 - 0.026 14.0 7.7 0.046 13.2 5.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 GAM22268.1 - 0.083 12.6 4.5 0.16 11.7 3.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 GAM22268.1 - 0.099 12.9 10.3 0.21 11.9 7.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.7 GAM22268.1 - 0.13 11.9 4.7 0.2 11.3 3.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAM22268.1 - 0.52 8.1 5.9 0.8 7.5 4.1 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 GAM22268.1 - 0.57 9.7 7.8 0.89 9.1 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SSP160 PF06933.6 GAM22268.1 - 1.5 6.6 15.6 2 6.2 10.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CENP-B_dimeris PF09026.5 GAM22268.1 - 2.4 8.4 15.2 6.4 7.0 10.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 GAM22268.1 - 2.7 5.9 4.5 4.1 5.3 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-Di19 PF05605.7 GAM22268.1 - 9.6 6.4 19.5 0.16 12.1 0.5 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Ral PF11058.3 GAM22269.1 - 9.1 5.7 8.7 7.4 6.0 0.5 3.1 3 0 0 3 3 3 0 Antirestriction protein Ral Methyltransf_11 PF08241.7 GAM22270.1 - 2.7e-15 56.6 0.0 5.6e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM22270.1 - 1e-07 31.8 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM22270.1 - 1.7e-07 31.5 0.0 4.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM22270.1 - 2e-07 31.5 0.0 3.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM22270.1 - 8.7e-07 28.6 0.0 1.2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM22270.1 - 1.7e-06 27.3 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAM22270.1 - 2.1e-05 24.5 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM22270.1 - 5.3e-05 23.5 0.0 0.00017 21.9 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 GAM22270.1 - 0.00028 19.9 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 GAM22270.1 - 0.00079 19.1 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase FtsJ PF01728.14 GAM22270.1 - 0.056 13.4 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase AAA PF00004.24 GAM22271.1 - 4e-50 169.4 0.1 8.2e-35 119.8 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM22271.1 - 1e-10 41.9 0.8 1.6e-05 24.9 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 GAM22271.1 - 5.9e-09 35.9 0.0 0.00038 20.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM22271.1 - 4.1e-07 30.8 0.1 0.0012 19.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM22271.1 - 1e-06 28.8 1.1 0.00049 20.2 0.1 4.1 2 2 2 4 4 3 1 AAA domain Arch_ATPase PF01637.13 GAM22271.1 - 9.4e-06 25.4 0.2 0.62 9.7 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase RuvB_N PF05496.7 GAM22271.1 - 1e-05 24.7 0.0 0.001 18.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 GAM22271.1 - 2.8e-05 24.0 0.0 0.00024 21.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAM22271.1 - 3.1e-05 23.4 0.0 0.0061 15.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 GAM22271.1 - 3.8e-05 23.4 0.2 0.00049 19.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 GAM22271.1 - 7.9e-05 21.6 0.0 0.067 12.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 GAM22271.1 - 0.00012 22.4 0.0 0.053 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM22271.1 - 0.00013 21.9 0.0 0.06 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM22271.1 - 0.00014 20.6 0.1 0.0083 14.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 GAM22271.1 - 0.0002 20.8 1.4 2.2 7.6 0.1 3.6 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 GAM22271.1 - 0.00069 19.7 0.0 0.9 9.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.1 GAM22271.1 - 0.00089 18.9 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 GAM22271.1 - 0.0012 18.0 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 GAM22271.1 - 0.0022 17.1 0.4 0.21 10.6 0.0 3.4 3 1 0 4 4 4 1 KaiC AAA_33 PF13671.1 GAM22271.1 - 0.0025 17.7 0.0 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAM22271.1 - 0.0066 16.0 0.1 0.19 11.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 GAM22271.1 - 0.0068 16.0 0.3 2 8.0 0.0 3.7 2 2 1 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 GAM22271.1 - 0.0068 15.8 0.1 0.12 11.8 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain ATP-synt_ab PF00006.20 GAM22271.1 - 0.0095 15.4 0.2 0.94 8.9 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 GAM22271.1 - 0.01 14.9 0.2 0.084 11.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Bac_DnaA PF00308.13 GAM22271.1 - 0.013 15.1 0.1 0.46 10.1 0.0 3.1 3 1 0 3 3 3 0 Bacterial dnaA protein NB-ARC PF00931.17 GAM22271.1 - 0.018 13.8 0.1 6.2 5.5 0.0 3.3 3 0 0 3 3 3 0 NB-ARC domain Parvo_NS1 PF01057.12 GAM22271.1 - 0.019 13.8 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 GAM22271.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 GAM22271.1 - 0.03 13.5 0.2 0.11 11.7 0.0 2.0 2 0 0 2 2 1 0 PhoH-like protein Zot PF05707.7 GAM22271.1 - 0.044 13.2 0.0 0.46 9.9 0.0 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 GAM22271.1 - 0.12 12.6 0.1 18 5.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Mlp PF03304.8 GAM22272.1 - 0.066 13.2 1.2 0.081 12.9 0.8 1.2 1 0 0 1 1 1 0 Mlp lipoprotein family NETI PF14044.1 GAM22272.1 - 0.12 11.9 0.2 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 NETI protein SapB_1 PF05184.10 GAM22272.1 - 0.14 11.9 1.3 0.35 10.7 0.3 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 Zip PF02535.17 GAM22274.1 - 0.31 10.0 5.4 0.37 9.7 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 GAM22274.1 - 3.8 7.3 5.8 5.5 6.7 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Methyltransf_18 PF12847.2 GAM22275.1 - 0.0028 18.2 0.0 0.0058 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM22275.1 - 0.0048 17.3 0.1 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM22275.1 - 0.058 13.7 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM22275.1 - 0.15 12.5 0.0 0.15 12.5 0.0 2.7 3 1 0 3 3 3 0 Methyltransferase domain SLX9 PF15341.1 GAM22275.1 - 2.2 8.7 11.4 3.5 8.0 4.7 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 RPN7 PF10602.4 GAM22276.1 - 0.057 12.7 0.1 2.3 7.5 0.0 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Trypan_PARP PF05887.6 GAM22277.1 - 2.6 7.8 13.8 3.7 7.3 9.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SLX9 PF15341.1 GAM22278.1 - 1.4e-19 70.7 14.1 1.4e-19 70.7 9.7 2.3 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 PhyH PF05721.8 GAM22279.1 - 6.3e-27 94.9 0.1 8.2e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4508 PF14969.1 GAM22280.1 - 0.019 14.9 0.0 0.21 11.5 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4508) HEAT_EZ PF13513.1 GAM22281.1 - 9.4e-25 86.4 13.4 1.1e-09 38.4 0.0 9.8 7 1 3 10 10 9 4 HEAT-like repeat HEAT_2 PF13646.1 GAM22281.1 - 5.5e-21 74.6 0.3 0.0011 19.1 0.0 6.5 3 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 GAM22281.1 - 3.2e-16 57.8 19.4 0.006 16.5 0.0 11.0 12 0 0 12 12 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM22281.1 - 6.6e-13 48.8 0.6 0.1 13.0 0.0 6.1 3 2 2 5 5 5 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 GAM22281.1 - 3.2e-10 40.1 8.7 0.013 15.4 0.0 6.0 6 2 1 7 7 6 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAM22281.1 - 3.1e-06 26.8 16.5 0.69 9.8 0.0 7.3 8 0 0 8 8 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 GAM22281.1 - 0.00026 19.4 10.4 0.069 11.4 0.2 4.0 3 1 0 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.3 GAM22281.1 - 0.00032 19.5 10.8 3 6.4 0.2 6.0 5 1 2 7 7 7 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.3 GAM22281.1 - 0.0029 17.5 0.7 1.9 8.3 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3385) DUF2435 PF10363.4 GAM22281.1 - 0.011 15.5 0.3 2.1 8.2 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2435) DUF2453 PF10507.4 GAM22281.1 - 0.014 15.1 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) IBN_N PF03810.14 GAM22281.1 - 0.022 14.6 0.5 0.12 12.3 0.1 2.6 2 0 0 2 2 1 0 Importin-beta N-terminal domain Katanin_con80 PF13925.1 GAM22281.1 - 0.031 14.0 0.7 2.1 8.0 0.1 2.6 1 1 1 2 2 2 0 con80 domain of Katanin Vfa1 PF08432.5 GAM22281.1 - 0.033 14.2 9.3 0.053 13.5 6.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLASP_N PF12348.3 GAM22281.1 - 0.035 13.4 2.5 18 4.5 0.0 4.6 4 1 2 6 6 5 0 CLASP N terminal DUF3437 PF11919.3 GAM22281.1 - 0.11 12.1 0.0 1.3 8.8 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF3437) Nop14 PF04147.7 GAM22281.1 - 0.24 9.2 12.7 0.38 8.6 8.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2454 PF10521.4 GAM22281.1 - 0.31 9.9 10.2 5.9 5.8 0.1 4.4 5 1 0 5 5 5 0 Protein of unknown function (DUF2454) Sporozoite_P67 PF05642.6 GAM22281.1 - 0.56 7.9 2.5 0.82 7.4 1.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 GAM22281.1 - 0.89 9.2 5.6 1.8 8.2 3.9 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 GAM22281.1 - 2.3 7.1 8.2 3.9 6.3 5.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 GAM22281.1 - 4.2 5.2 11.8 6.9 4.5 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2462 PF09495.5 GAM22282.1 - 0.047 14.4 21.4 0.038 14.7 12.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) Gelsolin PF00626.17 GAM22283.1 - 2.9e-23 81.3 0.4 4.9e-08 32.5 0.0 6.1 5 0 0 5 5 5 4 Gelsolin repeat SSP160 PF06933.6 GAM22283.1 - 0.66 7.8 6.3 1.4 6.8 4.4 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ADK PF00406.17 GAM22284.1 - 4e-58 195.5 0.0 5e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAM22284.1 - 2.6e-14 52.5 0.0 5.3e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 GAM22284.1 - 2e-05 25.3 0.0 3.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM22284.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM22284.1 - 0.0077 15.3 0.0 0.03 13.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAM22284.1 - 0.033 14.4 0.1 0.064 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2365 PF10157.4 GAM22285.1 - 4.7e-11 42.7 5.2 1.9e-10 40.8 3.6 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) Sir1 PF11603.3 GAM22285.1 - 0.016 15.3 0.2 0.051 13.7 0.0 1.9 2 0 0 2 2 2 0 Regulatory protein Sir1 E2F_TDP PF02319.15 GAM22286.1 - 5.7e-20 70.6 0.1 1.2e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Dak1 PF02733.12 GAM22287.1 - 3.8e-100 334.6 2.4 5.5e-100 334.0 1.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 GAM22287.1 - 1.1e-45 155.3 0.0 2.2e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain ASCH PF04266.9 GAM22287.1 - 2.3e-13 50.4 0.0 4.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 ASCH domain C2 PF00168.25 GAM22288.1 - 5.6e-16 58.1 0.1 2.3e-15 56.1 0.3 2.0 2 0 0 2 2 2 1 C2 domain Membr_traf_MHD PF10540.4 GAM22288.1 - 1.8e-08 34.2 0.0 9.5e-08 31.9 0.0 2.4 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain GRAM PF02893.15 GAM22288.1 - 0.0002 20.7 0.0 0.00063 19.2 0.0 1.9 1 0 0 1 1 1 1 GRAM domain SPC25 PF06703.6 GAM22289.1 - 6.4e-36 123.3 0.0 8.5e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4401 PF14351.1 GAM22289.1 - 0.031 13.2 0.3 0.041 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Caps_synth_CapC PF14102.1 GAM22289.1 - 0.066 13.3 0.3 0.2 11.8 0.1 1.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC Homez PF11569.3 GAM22289.1 - 0.092 11.8 0.0 5.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Lactamase_B PF00753.22 GAM22290.1 - 1.1e-12 48.0 0.4 1.7e-12 47.3 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM22290.1 - 3.1e-05 23.6 0.2 8.2e-05 22.2 0.2 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF1993 PF09351.5 GAM22291.1 - 0.014 15.2 0.4 0.014 15.2 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) Mitofilin PF09731.4 GAM22292.1 - 1.3e-46 159.4 30.1 2.2e-46 158.7 20.9 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TPR_14 PF13428.1 GAM22292.1 - 0.16 12.6 1.5 7.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.24 GAM22294.1 - 1.8e-11 43.5 27.2 1.4e-09 37.5 6.5 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 GAM22294.1 - 0.0038 16.5 6.3 0.0038 16.5 4.4 2.5 2 0 0 2 2 2 1 PHD-finger PP-binding PF00550.20 GAM22295.1 - 1.9e-10 40.8 0.1 2.4e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 GAM22295.1 - 0.00019 21.3 0.4 0.00032 20.6 0.3 1.4 1 1 0 1 1 1 1 Acyl-carrier LRR_6 PF13516.1 GAM22296.1 - 1.6e-12 46.1 40.5 0.018 15.0 0.1 10.9 11 1 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 GAM22296.1 - 5.1e-11 41.9 35.0 3.5e-05 23.2 1.3 8.2 7 2 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM22296.1 - 3e-05 23.6 33.7 0.0067 16.1 0.1 8.0 7 2 1 8 8 8 3 Leucine rich repeat LRR_1 PF00560.28 GAM22296.1 - 0.00063 19.4 30.5 1.8 8.8 0.0 10.3 11 2 1 12 12 12 3 Leucine Rich Repeat DUF566 PF04484.7 GAM22296.1 - 0.0034 16.9 9.1 0.0034 16.9 6.3 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF566) PK PF00224.16 GAM22296.1 - 0.021 13.4 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain LRR_7 PF13504.1 GAM22296.1 - 0.15 12.3 31.8 8.9 7.0 0.1 10.0 10 3 0 10 10 10 0 Leucine rich repeat DUF3504 PF12012.3 GAM22296.1 - 0.22 11.2 16.2 0.023 14.4 1.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3504) DUF605 PF04652.11 GAM22296.1 - 0.79 9.0 24.2 0.29 10.5 1.8 2.1 2 0 0 2 2 2 0 Vta1 like Hexokinase_1 PF00349.16 GAM22297.1 - 0.0035 16.6 0.1 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Hexokinase PPR PF01535.15 GAM22297.1 - 0.099 12.6 0.1 2.3 8.3 0.0 3.1 3 0 0 3 3 3 0 PPR repeat PhoU PF01895.14 GAM22297.1 - 0.1 13.0 2.1 0.2 12.0 0.0 2.5 3 0 0 3 3 3 0 PhoU domain Thg1C PF14413.1 GAM22298.1 - 1.2e-47 160.5 0.8 1.7e-47 160.0 0.5 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 GAM22298.1 - 2.2e-47 160.0 0.2 3e-47 159.6 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Kelch_6 PF13964.1 GAM22299.1 - 4.4e-09 36.1 14.2 0.00041 20.3 0.0 5.5 3 1 3 6 6 6 3 Kelch motif Kelch_1 PF01344.20 GAM22299.1 - 9.5e-06 25.0 7.3 1 8.9 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM22299.1 - 0.002 17.8 12.3 1.8 8.3 0.1 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF1900 PF08954.6 GAM22299.1 - 0.006 16.0 0.3 0.03 13.8 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1900) ACDC PF14733.1 GAM22299.1 - 0.0066 16.5 1.6 0.0066 16.5 1.1 3.3 4 0 0 4 4 4 1 AP2-coincident C-terminal Kelch_2 PF07646.10 GAM22299.1 - 0.0071 16.0 1.0 17 5.3 0.0 3.7 3 0 0 3 3 3 0 Kelch motif Baculo_PEP_C PF04513.7 GAM22299.1 - 0.046 13.5 12.1 0.037 13.8 7.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AF0941-like PF14591.1 GAM22299.1 - 0.078 13.0 1.1 0.21 11.6 0.8 1.6 1 0 0 1 1 1 0 AF0941-like Kelch_3 PF13415.1 GAM22299.1 - 0.11 12.7 9.6 27 5.0 0.0 5.5 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM22299.1 - 0.2 11.6 12.8 0.45 10.5 0.2 4.3 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.1 GAM22300.1 - 9e-13 47.8 2.3 2.6e-05 24.1 0.0 3.5 2 2 1 3 3 3 3 Kelch motif Kelch_4 PF13418.1 GAM22300.1 - 3e-08 33.2 0.2 2.1e-05 24.1 0.0 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22300.1 - 7.5e-08 31.7 0.1 0.024 14.1 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM22300.1 - 6e-07 29.4 0.0 0.012 15.7 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM22300.1 - 0.00074 19.1 0.0 0.18 11.6 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM22300.1 - 0.0039 17.1 1.1 13 5.8 0.0 3.3 3 0 0 3 3 3 2 Kelch motif BTB PF00651.26 GAM22301.1 - 7.5e-19 67.7 0.2 1.7e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.21 GAM22301.1 - 1.4e-06 28.5 4.5 1.8e-06 28.1 0.2 2.7 3 0 0 3 3 3 1 MATH domain BACK PF07707.10 GAM22301.1 - 1.4e-05 24.8 0.0 4.4e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 BTB And C-terminal Kelch Ribosomal_L34e PF01199.13 GAM22302.1 - 2.1e-38 130.4 5.8 2.1e-38 130.4 4.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e zinc-ribbons_6 PF07191.7 GAM22302.1 - 0.011 15.4 0.3 0.65 9.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 GAM22302.1 - 0.15 11.9 1.1 0.47 10.4 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain ZZ PF00569.12 GAM22302.1 - 0.16 11.5 1.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type Glyco_transf_10 PF00852.14 GAM22303.1 - 1.2e-54 185.1 6.6 1.7e-54 184.7 4.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) PPTA PF01239.17 GAM22305.1 - 1.5e-18 65.2 8.6 5e-05 22.4 0.5 6.0 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat TRM PF02005.11 GAM22306.1 - 1.2e-126 422.6 0.1 1.5e-126 422.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf-CCCH PF00642.19 GAM22306.1 - 0.00067 19.2 4.0 0.0012 18.4 0.8 2.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Met_10 PF02475.11 GAM22306.1 - 0.0018 17.8 0.1 0.003 17.1 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Pox_A51 PF04948.8 GAM22306.1 - 0.04 12.6 0.8 0.067 11.8 0.6 1.3 1 0 0 1 1 1 0 Poxvirus A51 protein PrmA PF06325.8 GAM22306.1 - 0.067 12.2 0.0 0.067 12.2 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) SNF2_N PF00176.18 GAM22307.1 - 1.8e-78 263.4 0.3 1.8e-78 263.4 0.2 4.1 4 0 0 4 4 4 1 SNF2 family N-terminal domain Bromodomain PF00439.20 GAM22307.1 - 3.9e-21 74.7 1.6 1.2e-20 73.2 0.2 2.5 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 GAM22307.1 - 1.8e-15 56.5 1.9 4.9e-15 55.1 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 GAM22307.1 - 1.1e-13 50.7 10.6 1.1e-13 50.7 7.4 4.0 2 1 2 4 4 4 1 HSA Peptidase_S8 PF00082.17 GAM22308.1 - 1.6e-40 139.0 2.8 2.4e-40 138.4 2.0 1.2 1 0 0 1 1 1 1 Subtilase family FANCI_S1-cap PF14674.1 GAM22309.1 - 0.058 13.4 0.1 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FANCI solenoid 1 cap PYST-C1 PF09690.5 GAM22309.1 - 0.48 10.0 7.9 0.74 9.4 5.5 1.3 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) SRP19 PF01922.12 GAM22310.1 - 6.1e-26 90.8 0.0 8.6e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein DUF904 PF06005.7 GAM22311.1 - 0.043 14.1 3.8 0.072 13.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AKNA PF12443.3 GAM22311.1 - 0.045 13.7 1.0 0.6 10.1 0.5 2.4 1 1 1 2 2 2 0 AT-hook-containing transcription factor TPR_MLP1_2 PF07926.7 GAM22311.1 - 0.079 12.6 2.5 0.14 11.9 1.0 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 GAM22311.1 - 0.14 12.0 1.6 0.23 11.3 0.6 1.7 1 1 0 1 1 1 0 Basic region leucine zipper NEMO PF11577.3 GAM22311.1 - 0.47 10.2 3.6 11 5.8 2.1 2.8 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO SynMuv_product PF06047.6 GAM22312.1 - 1.8e-46 156.1 3.0 1.8e-46 156.1 2.1 2.6 3 0 0 3 3 3 1 Ras-induced vulval development antagonist RCC1 PF00415.13 GAM22313.1 - 3.8e-37 126.2 3.8 4.2e-13 49.2 0.0 7.2 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM22313.1 - 1.1e-28 98.1 14.1 3.1e-10 39.3 0.0 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat KOW PF00467.24 GAM22314.1 - 1e-06 28.1 3.3 1e-06 28.1 2.3 2.0 3 0 0 3 3 3 1 KOW motif Urm1 PF09138.6 GAM22315.1 - 4e-33 113.4 0.1 4.6e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 GAM22315.1 - 0.00027 21.3 0.0 0.00043 20.6 0.0 1.4 1 1 0 1 1 1 1 ThiS family EF-hand_7 PF13499.1 GAM22315.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_C12 PF01088.16 GAM22315.1 - 0.12 11.5 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DnaJ PF00226.26 GAM22316.1 - 8.4e-10 38.2 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 GAM22316.1 - 8.3e-06 25.6 0.1 1.1e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Pam16 Mito_carr PF00153.22 GAM22317.1 - 5.3e-66 218.3 4.2 1.1e-23 82.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad52_Rad22 PF04098.10 GAM22318.1 - 3.9e-07 29.9 0.0 1.1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.17 GAM22318.1 - 4.6e-06 26.1 0.0 8.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22318.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22318.1 - 0.0044 16.8 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 GAM22318.1 - 0.14 11.5 10.4 0.32 10.4 7.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BK_channel_a PF03493.13 GAM22319.1 - 3.1e-24 84.8 1.0 4.4e-22 77.9 0.1 2.8 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 GAM22319.1 - 8.4e-14 51.0 8.6 8.7e-14 51.0 4.4 2.3 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.13 GAM22319.1 - 6.2e-08 32.6 0.0 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.26 GAM22319.1 - 1.7e-06 27.4 21.7 4.8e-05 22.7 9.2 3.1 2 1 1 3 3 3 2 Ion transport protein Mito_fiss_reg PF05308.6 GAM22319.1 - 0.38 10.0 14.2 0.075 12.3 1.9 2.5 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF3592 PF12158.3 GAM22320.1 - 0.00033 20.4 0.3 0.0021 17.8 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3592) DUF3169 PF11368.3 GAM22320.1 - 0.018 14.2 1.0 0.057 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) CaKB PF03185.10 GAM22320.1 - 0.17 11.2 3.4 12 5.2 0.2 3.1 2 1 1 3 3 3 0 Calcium-activated potassium channel, beta subunit DUF1049 PF06305.6 GAM22320.1 - 0.22 11.0 0.0 0.22 11.0 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Pkinase PF00069.20 GAM22323.1 - 3e-47 160.9 0.1 3e-47 160.9 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22323.1 - 2.8e-25 88.8 0.0 3.6e-24 85.2 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM22323.1 - 0.044 12.8 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 GAM22323.1 - 0.085 12.2 16.9 0.018 14.4 9.6 1.4 2 0 0 2 2 2 0 Vta1 like Spc7_N PF15402.1 GAM22323.1 - 0.55 8.1 17.4 0.85 7.5 12.1 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DDHD PF02862.12 GAM22323.1 - 2.2 8.0 10.8 1 9.0 5.5 1.8 2 0 0 2 2 2 0 DDHD domain PB1 PF00564.19 GAM22324.1 - 4.1e-15 55.2 0.2 6.7e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Acetyltransf_1 PF00583.19 GAM22325.1 - 1.7e-15 56.7 0.0 2.9e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM22325.1 - 1.2e-10 41.3 0.0 2.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM22325.1 - 3.1e-07 30.5 0.0 7.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM22325.1 - 1.4e-06 28.0 0.0 2.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 GAM22325.1 - 3.9e-05 23.6 0.0 8.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM22325.1 - 4.4e-05 23.3 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM22325.1 - 0.0076 16.1 0.1 0.048 13.5 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM22325.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GATA PF00320.22 GAM22326.1 - 6.6e-15 54.1 5.1 2.1e-14 52.5 3.5 1.9 1 0 0 1 1 1 1 GATA zinc finger Tir_receptor_C PF07489.6 GAM22326.1 - 9.6 5.8 21.3 0.046 13.4 3.9 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus GlcNAc PF11397.3 GAM22327.1 - 4.8e-88 295.5 0.0 5.5e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) CH PF00307.26 GAM22330.1 - 2.3e-12 46.9 0.6 2.2e-05 24.4 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain Presenilin PF01080.12 GAM22330.1 - 0.00065 18.6 4.7 0.00065 18.6 3.3 3.7 1 1 0 2 2 2 1 Presenilin FGF-BP1 PF06473.7 GAM22330.1 - 0.0041 16.7 7.0 0.0041 16.7 4.9 4.2 1 1 1 4 4 4 1 FGF binding protein 1 (FGF-BP1) LRR19-TM PF15176.1 GAM22330.1 - 4.8 6.9 5.9 1.1 8.9 0.1 2.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PQ-loop PF04193.9 GAM22331.1 - 6.2e-21 73.7 11.9 7.9e-14 50.9 1.1 3.3 3 1 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 GAM22331.1 - 0.018 14.8 12.1 0.49 10.2 2.1 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange zf-C2H2_jaz PF12171.3 GAM22332.1 - 2.1e-06 27.7 2.4 5.5e-06 26.3 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM22332.1 - 9.7e-06 25.6 2.9 2.7e-05 24.1 2.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 GAM22332.1 - 0.013 15.6 2.2 0.041 13.9 1.6 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 GAM22332.1 - 0.019 14.6 2.5 0.054 13.1 1.7 1.8 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_6 PF13912.1 GAM22332.1 - 0.021 14.7 0.4 0.053 13.4 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 GAM22332.1 - 0.64 10.4 3.3 0.79 10.1 0.9 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM22332.1 - 3.2 8.2 5.0 1.6 9.2 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Cupin_8 PF13621.1 GAM22333.1 - 1.5e-50 172.0 0.7 2.4e-50 171.3 0.0 1.6 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 GAM22333.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 GAM22333.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF2976 PF11190.3 GAM22334.1 - 0.021 14.3 0.1 0.045 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Syndecan PF01034.15 GAM22334.1 - 0.35 10.5 1.5 0.7 9.5 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain DnaJ PF00226.26 GAM22336.1 - 5.5e-24 83.6 1.0 6.9e-24 83.3 0.7 1.1 1 0 0 1 1 1 1 DnaJ domain CsiD PF08943.5 GAM22336.1 - 0.025 13.5 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 CsiD CTDII PF01556.13 GAM22337.1 - 5.5e-23 80.6 0.5 1.6e-20 72.7 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAM22337.1 - 4.9e-16 58.5 20.7 8.3e-16 57.8 14.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAM22337.1 - 0.012 15.2 9.7 0.076 12.7 1.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family GldM_C PF12080.3 GAM22337.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 1 0 1 1 1 0 GldM C-terminal domain zf-IS66 PF13005.2 GAM22337.1 - 0.19 11.7 0.4 0.19 11.7 0.2 3.9 2 2 2 4 4 4 0 zinc-finger binding domain of transposase IS66 DZR PF12773.2 GAM22337.1 - 0.99 9.2 13.7 77 3.2 9.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 GAM22337.1 - 1.7 8.7 10.3 5.7 7.0 0.3 3.3 2 1 0 2 2 2 0 zinc-finger zf-C3HC4_3 PF13920.1 GAM22337.1 - 2.6 7.7 11.7 0.095 12.3 1.3 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RhoGEF PF00621.15 GAM22338.1 - 2e-52 177.6 1.9 3.1e-52 177.0 1.3 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAM22338.1 - 1.9e-21 75.7 7.8 1.9e-21 75.7 5.4 2.3 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 GAM22338.1 - 4.8e-10 39.5 0.0 1.2e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.11 GAM22338.1 - 0.0018 18.1 4.7 0.0018 18.1 3.3 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger zf-B_box PF00643.19 GAM22338.1 - 6.8 6.6 11.2 1.8 8.4 4.8 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-MYND PF01753.13 GAM22339.1 - 6e-08 32.4 16.1 9.1e-08 31.8 11.2 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 GAM22339.1 - 0.02 14.7 6.8 0.038 13.8 4.7 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3624 PF12292.3 GAM22339.1 - 0.38 11.1 6.7 0.57 10.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) RCR PF12273.3 GAM22340.1 - 8.9 6.8 27.1 1.6 9.3 15.5 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red XdhC_C PF13478.1 GAM22341.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.0 1 0 0 1 1 1 0 XdhC Rossmann domain Glyco_hydro_20 PF00728.17 GAM22342.1 - 6.9e-79 265.5 1.2 8.9e-79 265.1 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM22342.1 - 4e-22 79.2 0.0 7.6e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM22342.1 - 1.8e-05 25.3 0.0 2.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Peptidase_M8 PF01457.11 GAM22343.1 - 4.7e-47 160.5 0.8 6.4e-47 160.0 0.5 1.2 1 0 0 1 1 1 1 Leishmanolysin Zip PF02535.17 GAM22343.1 - 0.033 13.1 1.2 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Coatomer_WDAD PF04053.9 GAM22344.1 - 4.5e-07 29.0 0.5 0.056 12.2 0.1 3.2 3 0 0 3 3 3 2 Coatomer WD associated region WD40 PF00400.27 GAM22344.1 - 9e-07 28.5 0.0 4.1e-05 23.2 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-met PF12874.2 GAM22345.1 - 1.1e-05 25.4 1.0 1.9e-05 24.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 GAM22345.1 - 0.00037 20.0 0.1 0.00056 19.5 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein IF4E PF01652.13 GAM22347.1 - 7.8e-39 132.8 1.8 1.2e-38 132.2 1.2 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E Bac_small_YrzI PF09501.5 GAM22347.1 - 0.21 11.5 8.0 3.3 7.7 2.9 3.1 2 1 1 3 3 3 0 Probable sporulation protein (Bac_small_yrzI) Bap31 PF05529.7 GAM22347.1 - 0.43 10.0 4.6 0.13 11.6 0.7 1.8 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like AAA_32 PF13654.1 GAM22347.1 - 1.2 7.6 9.1 0.75 8.3 2.0 2.3 3 0 0 3 3 3 0 AAA domain Acyltransferase PF01553.16 GAM22349.1 - 2.1e-05 23.9 0.1 0.00015 21.2 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase Phytoreo_Pns PF05451.6 GAM22349.1 - 0.032 12.8 0.4 0.083 11.5 0.1 1.7 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns10/11 DUF1049 PF06305.6 GAM22351.1 - 0.0092 15.4 2.4 0.022 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) CaKB PF03185.10 GAM22351.1 - 0.034 13.5 1.9 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit Glyco_hydro_14 PF01373.12 GAM22352.1 - 1.5e-113 379.6 1.9 1.7e-113 379.4 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 DUF3872 PF12988.2 GAM22352.1 - 0.079 12.4 0.2 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3872) Peptidase_M41 PF01434.13 GAM22352.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 UPF0029 PF01205.14 GAM22353.1 - 1.9e-30 104.7 1.2 2.7e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 GAM22353.1 - 8.8e-16 57.8 1.4 4.5e-15 55.5 0.5 2.2 2 0 0 2 2 2 1 RWD domain Ribosomal_L39 PF00832.15 GAM22354.1 - 1.6e-22 78.6 9.9 1.8e-22 78.4 6.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Toxin_YhaV PF11663.3 GAM22354.1 - 0.26 11.0 1.8 0.39 10.4 1.2 1.4 1 1 0 1 1 1 0 Toxin with endonuclease activity YhaV Sec10 PF07393.6 GAM22355.1 - 1.6e-101 340.7 31.5 3e-52 177.7 7.0 2.8 2 1 1 3 3 3 2 Exocyst complex component Sec10 DUF1664 PF07889.7 GAM22355.1 - 0.0022 17.7 1.2 0.041 13.6 0.0 3.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) FliJ PF02050.11 GAM22355.1 - 0.42 10.6 8.1 0.59 10.2 1.3 2.8 2 0 0 2 2 2 0 Flagellar FliJ protein WD40 PF00400.27 GAM22356.1 - 2.3e-14 52.6 11.3 3.9e-05 23.3 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM22356.1 - 6e-05 22.6 1.0 0.049 13.0 0.0 3.0 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 GAM22356.1 - 0.008 14.3 0.7 0.03 12.4 0.1 1.9 1 1 0 2 2 2 1 Nucleoporin Nup120/160 CENP-H PF05837.7 GAM22356.1 - 0.088 12.9 3.8 0.27 11.4 2.7 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CCDC74_C PF14917.1 GAM22356.1 - 0.12 12.4 4.1 0.21 11.6 2.8 1.3 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal PQQ_3 PF13570.1 GAM22356.1 - 0.33 11.3 7.0 7 7.0 0.1 4.6 4 1 1 5 5 5 0 PQQ-like domain DivIC PF04977.10 GAM22356.1 - 3.1 7.3 5.2 2.1 7.8 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator ICAP-1_inte_bdg PF10480.4 GAM22357.1 - 9.5 5.9 7.9 12 5.5 5.5 1.1 1 0 0 1 1 1 0 Beta-1 integrin binding protein Med15 PF09606.5 GAM22358.1 - 0.00017 19.9 0.2 0.00017 19.9 0.2 3.4 2 1 1 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.7 GAM22358.1 - 0.87 8.1 15.1 1.6 7.2 10.4 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2201 PF09967.4 GAM22359.1 - 1e-10 41.6 0.0 2.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) VWA_2 PF13519.1 GAM22359.1 - 4e-08 33.5 0.0 2.3e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM22359.1 - 4.3e-07 29.8 0.1 1.1e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 GAM22359.1 - 0.00012 21.3 0.1 0.0023 17.1 0.0 2.5 2 1 0 2 2 2 1 VWA domain containing CoxE-like protein Tbf5 PF06331.7 GAM22360.1 - 3.3e-14 52.3 0.1 3.6e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ank_2 PF12796.2 GAM22361.1 - 2.9e-15 56.3 6.0 6.2e-06 26.4 1.2 6.6 3 2 2 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22361.1 - 5.7e-07 29.1 3.5 2.6 8.5 0.0 7.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.1 GAM22361.1 - 7.5e-06 26.3 6.7 0.094 13.2 0.0 7.2 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22361.1 - 0.00011 22.3 4.5 0.64 10.3 0.0 6.6 5 2 3 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM22361.1 - 0.00038 20.1 4.8 2.2 8.2 0.0 7.0 9 1 0 9 9 9 1 Ankyrin repeat TEA PF01285.13 GAM22361.1 - 0.2 10.7 0.4 0.3 10.1 0.3 1.2 1 0 0 1 1 1 0 TEA/ATTS domain family DUF3447 PF11929.3 GAM22361.1 - 0.3 10.9 26.7 1.2 9.0 2.6 6.6 4 3 1 6 6 6 0 Domain of unknown function (DUF3447) Ank_2 PF12796.2 GAM22362.1 - 1.2e-17 63.9 4.6 7.5e-06 26.1 0.1 5.6 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22362.1 - 2.2e-09 37.5 5.2 0.33 11.5 0.0 7.9 6 1 3 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22362.1 - 5.8e-09 35.3 6.4 13 6.3 0.0 9.3 9 1 1 10 10 10 2 Ankyrin repeat Ank PF00023.25 GAM22362.1 - 3e-06 26.7 5.3 4.8 7.1 0.1 7.9 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.1 GAM22362.1 - 4.9e-05 23.4 1.4 3.2 8.1 0.1 6.0 4 2 2 6 6 6 1 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM22362.1 - 0.0028 17.4 8.0 0.11 12.2 0.4 4.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3447) PAP2 PF01569.16 GAM22363.1 - 2.1e-22 79.1 1.3 2.1e-22 79.1 0.9 2.0 1 1 1 2 2 2 1 PAP2 superfamily PalH PF08733.5 GAM22363.1 - 0.043 12.6 0.3 0.08 11.7 0.2 1.5 1 0 0 1 1 1 0 PalH/RIM21 7tm_1 PF00001.16 GAM22363.1 - 0.06 12.4 2.5 0.061 12.4 0.7 1.7 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Coq4 PF05019.8 GAM22363.1 - 0.13 11.1 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PfkB PF00294.19 GAM22364.1 - 1.6e-14 53.7 0.0 3e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Dus PF01207.12 GAM22365.1 - 2.8e-70 236.6 0.0 3.7e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 GAM22365.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein PH_3 PF14593.1 GAM22366.1 - 2.9e-12 46.3 0.1 4.3e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 PH domain PH PF00169.24 GAM22366.1 - 1.9e-11 44.0 0.0 2.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM22366.1 - 0.0002 21.5 0.7 0.02 15.1 0.5 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM22366.1 - 0.0041 17.1 0.0 0.0055 16.7 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 GAM22366.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_4 PF12799.2 GAM22368.1 - 4e-15 55.0 32.6 8.6e-05 22.0 0.4 8.0 5 2 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM22368.1 - 5e-10 37.9 33.6 0.6 10.3 0.0 11.8 11 2 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 GAM22368.1 - 2.3e-09 36.3 37.6 2.6 8.3 0.0 12.2 11 1 1 12 12 12 6 Leucine Rich repeat LRR_7 PF13504.1 GAM22368.1 - 1.1e-06 27.8 26.2 5.4 7.6 0.7 11.2 10 0 0 10 10 10 2 Leucine rich repeat LRR_8 PF13855.1 GAM22368.1 - 3.4e-05 23.4 32.4 0.0013 18.4 0.7 7.7 1 1 10 11 11 11 6 Leucine rich repeat FIST PF08495.5 GAM22368.1 - 0.064 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 FIST N domain Proteasome PF00227.21 GAM22369.1 - 4.5e-34 117.4 0.0 5.9e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Mito_carr PF00153.22 GAM22370.1 - 2e-60 200.4 4.5 2.7e-26 91.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1689 PF07954.6 GAM22370.1 - 0.026 14.3 0.3 0.043 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) RAP1 PF07218.6 GAM22370.1 - 0.034 12.2 0.0 0.043 11.9 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BSD PF03909.12 GAM22371.1 - 1.1e-08 34.6 0.0 2.7e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 BSD domain Helicase_C_3 PF13625.1 GAM22372.1 - 1.9e-29 102.0 0.0 6.8e-29 100.2 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM22372.1 - 4.3e-12 46.2 0.0 9.2e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 GAM22372.1 - 3.7e-10 39.0 0.0 6.2e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM22372.1 - 2.3e-09 36.9 0.1 9.7e-09 34.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Phosducin PF02114.11 GAM22373.1 - 5.5e-07 28.5 0.6 5.9e-07 28.4 0.4 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 GAM22373.1 - 1.3e-06 28.0 0.2 2e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Fasciclin PF02469.17 GAM22373.1 - 0.043 13.8 0.4 0.095 12.7 0.2 1.6 2 1 0 2 2 2 0 Fasciclin domain Peptidase_M4 PF01447.13 GAM22373.1 - 0.044 13.9 0.2 0.073 13.1 0.0 1.5 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain FliT PF05400.8 GAM22373.1 - 0.07 13.5 0.8 0.13 12.6 0.5 1.5 1 0 0 1 1 1 0 Flagellar protein FliT Mito_carr PF00153.22 GAM22374.1 - 5e-56 186.4 0.7 2.6e-23 81.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Iso_dh PF00180.15 GAM22375.1 - 5.3e-86 288.7 1.9 6.1e-86 288.5 1.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YopJ PF03421.11 GAM22375.1 - 0.04 13.7 0.2 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase IQ PF00612.22 GAM22377.1 - 1.3e-08 33.7 9.1 5e-05 22.5 2.9 2.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif Rhamno_transf PF11316.3 GAM22377.1 - 0.012 14.8 1.0 0.019 14.2 0.7 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase SOG2 PF10428.4 GAM22377.1 - 1.8 7.0 18.6 2.5 6.6 12.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein HABP4_PAI-RBP1 PF04774.10 GAM22377.1 - 2.5 8.6 12.5 7.7 7.0 0.4 2.6 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family Hydrolase PF00702.21 GAM22379.1 - 6.1e-25 88.9 0.0 5.6e-24 85.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM22379.1 - 9.5e-24 83.7 0.0 2.8e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAM22379.1 - 3.4e-21 76.2 0.0 6.7e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM22379.1 - 1.2e-06 28.3 0.0 3.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM22379.1 - 0.0025 17.4 7.1 0.028 14.0 0.1 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM22379.1 - 0.097 12.8 0.0 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.15 GAM22380.1 - 2.1e-23 82.6 0.4 2.2e-12 46.7 0.0 3.0 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.1 GAM22380.1 - 2.4e-10 40.7 0.2 8.5e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM22380.1 - 0.001 19.1 0.0 0.028 14.5 0.0 2.9 1 1 1 2 2 2 1 AAA domain TPR_12 PF13424.1 GAM22380.1 - 0.0034 17.2 0.2 6.9 6.6 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF3439 PF11921.3 GAM22382.1 - 1.5 8.6 7.4 4.7 6.9 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Kelch_4 PF13418.1 GAM22383.1 - 1.5e-52 175.1 14.6 3.1e-10 39.6 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM22383.1 - 2.4e-48 161.2 11.1 1.6e-09 37.6 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM22383.1 - 1.9e-35 119.5 17.7 2.5e-09 36.9 0.0 6.3 3 2 3 6 6 6 5 Kelch motif Kelch_5 PF13854.1 GAM22383.1 - 2.7e-35 119.7 12.7 1.1e-08 34.8 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM22383.1 - 8.2e-34 114.9 12.6 1e-06 28.1 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM22383.1 - 4.1e-29 99.2 5.0 2.4e-05 23.9 0.0 5.9 6 0 0 6 6 6 5 Kelch motif K-box PF01486.12 GAM22383.1 - 8.4e-06 25.5 9.4 8.4e-06 25.5 6.5 3.2 3 0 0 3 3 3 1 K-box region Ank_2 PF12796.2 GAM22384.1 - 6.8e-06 26.3 0.0 0.0034 17.6 0.1 4.0 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22384.1 - 0.0008 19.4 0.1 60 4.3 0.0 5.8 4 1 1 5 5 5 0 Ankyrin repeat Ank_4 PF13637.1 GAM22384.1 - 0.00096 19.5 0.5 1.3 9.6 0.2 5.0 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22384.1 - 0.024 14.9 0.1 10 6.5 0.0 4.1 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Ras PF00071.17 GAM22385.1 - 2.1e-18 66.2 0.0 7.5e-17 61.1 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 GAM22385.1 - 1.1e-12 48.5 0.0 8.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM22385.1 - 2.9e-07 29.9 0.1 8.8e-06 25.0 0.0 2.2 1 1 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM22385.1 - 4.1e-06 26.7 0.1 9.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM22385.1 - 0.031 13.5 0.1 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM22385.1 - 0.042 13.6 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Dynamin family MobB PF03205.9 GAM22385.1 - 0.2 11.3 0.3 0.39 10.4 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YIF1 PF03878.10 GAM22386.1 - 5e-71 238.6 5.4 6.4e-71 238.2 3.7 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 GAM22386.1 - 3.7e-05 23.2 6.5 6.4e-05 22.5 4.5 1.4 1 0 0 1 1 1 1 Yip1 domain ubiquitin PF00240.18 GAM22387.1 - 6.4e-27 92.7 0.2 7.1e-27 92.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM22387.1 - 1e-18 66.7 0.2 1.1e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM22387.1 - 8.7e-06 25.9 0.1 3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 GAM22387.1 - 0.046 13.6 0.7 0.061 13.2 0.5 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain VWA_2 PF13519.1 GAM22388.1 - 1.1e-17 64.6 0.0 5e-17 62.5 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Ras PF00071.17 GAM22388.1 - 5.5e-07 29.1 0.1 0.00016 21.0 0.0 2.6 2 0 0 2 2 2 2 Ras family Miro PF08477.8 GAM22388.1 - 4e-05 24.0 0.0 0.4 11.1 0.0 2.8 1 1 1 2 2 2 2 Miro-like protein Claudin_3 PF06653.6 GAM22389.1 - 0.71 9.5 10.0 1.5 8.4 6.9 1.6 1 1 0 1 1 1 0 Tight junction protein, Claudin-like MRAP PF15183.1 GAM22389.1 - 0.88 9.2 3.6 0.74 9.4 0.1 2.4 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family DUF3464 PF11947.3 GAM22389.1 - 4.1 6.8 5.4 24 4.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) PQ-loop PF04193.9 GAM22390.1 - 0.024 14.1 0.3 0.024 14.1 0.2 2.4 3 0 0 3 3 3 0 PQ loop repeat LRR_8 PF13855.1 GAM22391.1 - 0.053 13.2 0.1 0.053 13.2 0.0 3.7 4 0 0 4 4 4 0 Leucine rich repeat FAM75 PF14650.1 GAM22391.1 - 0.39 10.0 1.7 0.64 9.3 1.2 1.2 1 0 0 1 1 1 0 FAM75 family LRR_4 PF12799.2 GAM22391.1 - 3.9 7.2 22.5 0.48 10.1 0.2 5.8 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) EGF_2 PF07974.8 GAM22392.1 - 0.0074 16.4 18.4 0.019 15.1 12.8 1.7 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.8 GAM22393.1 - 0.022 14.9 16.4 0.052 13.7 11.4 1.6 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM22393.1 - 0.31 11.0 10.3 0.74 9.8 7.2 1.6 1 0 0 1 1 1 0 EGF-like domain FA_hydroxylase PF04116.8 GAM22394.1 - 4.8e-15 55.9 12.9 4.8e-15 55.9 9.0 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily EB PF01683.13 GAM22395.1 - 0.0048 16.9 4.0 0.012 15.6 2.8 1.6 1 0 0 1 1 1 1 EB module EGF_2 PF07974.8 GAM22395.1 - 0.038 14.1 16.9 0.081 13.1 11.7 1.5 1 0 0 1 1 1 0 EGF-like domain EB PF01683.13 GAM22396.1 - 0.00083 19.3 4.9 0.0018 18.2 3.4 1.6 1 0 0 1 1 1 1 EB module TMEM154 PF15102.1 GAM22396.1 - 0.0029 17.3 0.3 0.0086 15.7 0.2 1.8 1 0 0 1 1 1 1 TMEM154 protein family EGF_2 PF07974.8 GAM22396.1 - 0.26 11.4 24.0 0.032 14.4 13.5 1.8 2 0 0 2 2 2 0 EGF-like domain EB PF01683.13 GAM22398.1 - 0.0005 20.0 3.4 0.0012 18.8 2.4 1.6 1 0 0 1 1 1 1 EB module DUF1191 PF06697.7 GAM22398.1 - 0.021 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EGF_2 PF07974.8 GAM22398.1 - 0.28 11.4 17.7 0.7 10.1 12.2 1.8 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM22398.1 - 2.3 8.2 12.5 8.2 6.5 8.7 2.0 1 0 0 1 1 1 0 EGF-like domain Ribosomal_L22e PF01776.12 GAM22399.1 - 2.4e-18 66.1 0.0 3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Snf7 PF03357.16 GAM22400.1 - 7e-28 97.1 29.2 7.3e-28 97.0 19.8 1.3 1 1 0 1 1 1 1 Snf7 PC-Esterase PF13839.1 GAM22400.1 - 0.22 11.3 2.3 0.29 10.9 1.6 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Alkyl_sulf_dimr PF14863.1 GAM22400.1 - 0.9 9.7 12.3 2.4 8.3 2.6 2.3 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Prefoldin_2 PF01920.15 GAM22400.1 - 0.98 9.2 21.1 3 7.6 1.7 3.1 1 1 3 4 4 4 0 Prefoldin subunit Nup54 PF13874.1 GAM22400.1 - 2.2 7.9 12.8 0.15 11.6 3.1 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 YlqD PF11068.3 GAM22400.1 - 2.8 7.9 19.9 0.17 11.8 6.8 2.2 1 1 1 2 2 2 0 YlqD protein Rgp1 PF08737.5 GAM22400.1 - 2.9 6.8 10.3 4.4 6.2 7.1 1.3 1 1 0 1 1 1 0 Rgp1 DUF4047 PF13256.1 GAM22400.1 - 8.8 6.3 13.5 7.1 6.6 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) SH3_2 PF07653.12 GAM22401.1 - 5.7e-15 54.5 0.0 1.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAM22401.1 - 1.6e-14 53.2 0.0 3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM22401.1 - 4e-14 51.7 0.0 7.2e-14 50.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Peroxin-13_N PF04088.8 GAM22401.1 - 3.6e-09 36.7 0.0 3.6e-09 36.7 0.0 2.4 2 1 0 2 2 2 1 Peroxin 13, N-terminal region DUF4407 PF14362.1 GAM22401.1 - 2.5 6.9 6.3 3.8 6.3 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PRP21_like_P PF12230.3 GAM22402.1 - 1.3e-38 132.8 22.9 1.3e-38 132.8 15.9 3.2 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 GAM22402.1 - 1.6e-36 123.7 3.1 2.9e-17 62.0 0.0 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 GAM22402.1 - 4.3e-10 38.8 0.8 8.7e-10 37.8 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 GAM22402.1 - 0.0014 18.8 2.2 0.0016 18.6 0.4 2.0 2 1 0 2 2 2 1 Ubiquitin-like domain UN_NPL4 PF11543.3 GAM22402.1 - 0.12 12.6 0.1 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mito_carr PF00153.22 GAM22403.1 - 3.6e-66 218.9 3.8 5.7e-22 77.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 GAM22403.1 - 0.21 11.9 1.5 3 8.2 0.0 2.3 2 0 0 2 2 2 0 YtxH-like protein HrpB7 PF09486.5 GAM22404.1 - 0.0069 16.3 4.7 0.0069 16.3 3.3 7.3 3 2 5 8 8 8 3 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 GAM22404.1 - 2.2 7.3 87.5 0.012 14.8 5.1 7.9 3 2 3 8 8 8 0 Reovirus sigma C capsid protein Histone PF00125.19 GAM22405.1 - 5.7e-20 71.2 0.0 8.8e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM22405.1 - 4.4e-09 36.2 0.2 6.2e-08 32.5 0.0 2.2 1 1 2 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Carb_anhydrase PF00194.16 GAM22407.1 - 0.026 13.4 1.1 0.043 12.8 0.8 1.4 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase CKAP2_C PF15297.1 GAM22407.1 - 0.61 8.8 7.9 0.3 9.8 2.4 2.0 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus DUF4614 PF15391.1 GAM22407.1 - 1.6 8.4 18.8 0.82 9.4 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Gcd10p PF04189.8 GAM22407.1 - 5.2 6.1 13.6 0.4 9.7 4.1 2.1 2 0 0 2 2 2 0 Gcd10p family Thiolase_N PF00108.18 GAM22408.1 - 2.6e-86 288.8 2.8 2.6e-86 288.8 1.9 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM22408.1 - 2.7e-47 159.1 0.9 6.4e-47 158.0 0.6 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM22408.1 - 0.00034 20.1 0.5 0.00072 19.1 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 GAM22408.1 - 0.0013 18.3 0.5 0.34 10.5 0.1 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Myosin_N PF02736.14 GAM22408.1 - 0.037 13.7 2.5 0.069 12.8 1.7 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain RasGEF PF00617.14 GAM22409.1 - 1.6e-56 191.0 0.5 4.2e-56 189.6 0.4 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM22409.1 - 1.7e-21 76.2 0.6 1.7e-21 76.2 0.4 3.2 3 0 0 3 3 3 1 RasGEF N-terminal motif Phe_hydrox_dim PF07976.7 GAM22410.1 - 0.044 13.3 0.3 0.066 12.8 0.2 1.4 1 1 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain YkyA PF10368.4 GAM22410.1 - 0.056 12.7 0.6 0.14 11.4 0.0 1.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Allexi_40kDa PF05549.6 GAM22410.1 - 0.15 11.2 6.3 0.23 10.7 3.7 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein Sigma70_ner PF04546.8 GAM22410.1 - 0.2 11.2 4.3 0.22 11.1 2.4 1.5 1 1 1 2 2 2 0 Sigma-70, non-essential region DUF3439 PF11921.3 GAM22410.1 - 0.33 10.7 6.4 0.51 10.0 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM22410.1 - 7.7 4.3 11.9 8.6 4.1 8.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ABC2_membrane_3 PF12698.2 GAM22412.1 - 3.2e-53 180.9 56.5 3.5e-28 98.6 16.3 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 GAM22412.1 - 1.3e-47 161.5 0.0 5.5e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM22412.1 - 1.9e-15 57.6 7.2 1.4e-06 28.5 0.0 4.9 4 1 0 5 5 5 2 AAA domain AAA_15 PF13175.1 GAM22412.1 - 7.9e-05 21.8 0.0 0.2 10.6 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.1 GAM22412.1 - 0.00038 20.3 0.0 0.088 12.7 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 GAM22412.1 - 0.00059 19.1 0.0 6.5 5.9 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM22412.1 - 0.0063 16.0 1.7 2.8 7.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 GAM22412.1 - 0.11 11.6 0.1 5.7 5.9 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 GAM22412.1 - 0.11 11.8 3.3 0.67 9.3 0.4 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 GAM22412.1 - 0.13 12.5 3.2 10 6.4 0.8 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAM22412.1 - 0.16 11.1 0.7 6.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM22412.1 - 0.39 10.0 0.3 3.5 6.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 GAM22412.1 - 1.1 8.3 45.3 0.051 12.7 11.5 3.7 3 1 1 4 4 4 0 ABC-2 type transporter ABC2_membrane_2 PF12679.2 GAM22412.1 - 8.1 5.2 36.7 2.4 6.9 8.2 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein Pro-kuma_activ PF09286.6 GAM22413.1 - 1.2e-23 83.7 0.1 3e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM22413.1 - 2.1e-08 33.6 0.8 4.1e-08 32.7 0.5 1.4 1 0 0 1 1 1 1 Subtilase family ABC_membrane PF00664.18 GAM22415.1 - 3e-59 200.6 43.1 1.3e-29 103.5 12.1 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM22415.1 - 1.8e-46 157.8 0.2 2.2e-27 96.0 0.0 3.2 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 GAM22415.1 - 5e-09 35.7 1.8 0.00076 18.7 0.1 4.0 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM22415.1 - 4.9e-06 26.7 9.4 0.051 13.5 0.0 6.0 4 2 1 5 5 5 1 AAA domain AAA_25 PF13481.1 GAM22415.1 - 9.8e-05 21.8 0.2 0.0097 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM22415.1 - 0.00043 19.5 0.1 0.095 11.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM22415.1 - 0.00085 18.8 10.0 0.29 10.6 0.0 4.4 5 0 0 5 5 5 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM22415.1 - 0.0024 17.8 1.3 2.1 8.3 0.1 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 GAM22415.1 - 0.011 16.2 2.8 0.31 11.5 0.1 3.3 3 0 0 3 3 3 0 Miro-like protein ArgK PF03308.11 GAM22415.1 - 0.023 13.4 0.5 3.8 6.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 GAM22415.1 - 0.036 14.0 0.4 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 GAM22415.1 - 0.16 11.5 1.6 0.25 10.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 GAM22415.1 - 0.24 10.4 2.8 3.8 6.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.12 GAM22415.1 - 0.31 10.8 6.4 0.16 11.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 GAM22415.1 - 0.66 9.7 2.3 4 7.2 0.4 2.9 3 0 0 3 3 3 0 Part of AAA domain AAA_23 PF13476.1 GAM22415.1 - 5.3 7.3 9.6 2.7 8.2 0.1 3.2 4 0 0 4 4 2 0 AAA domain Ank_2 PF12796.2 GAM22416.1 - 6.5e-39 132.1 1.0 1.1e-11 44.9 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM22416.1 - 2.7e-38 127.8 3.2 3e-07 29.9 0.1 8.8 7 2 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.1 GAM22416.1 - 6.6e-32 106.3 6.0 9e-06 25.4 0.0 10.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.1 GAM22416.1 - 2.9e-28 97.6 3.4 5.4e-07 29.9 0.0 7.1 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22416.1 - 6.7e-24 83.3 7.8 6e-08 32.6 0.0 7.2 5 3 3 8 8 8 6 Ankyrin repeats (many copies) FNIP PF05725.7 GAM22417.1 - 7.2e-59 195.5 26.1 1.5e-14 53.6 0.4 7.4 3 2 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM22417.1 - 0.0059 16.5 1.3 9.7 6.2 0.0 4.8 2 2 4 6 6 6 2 Protein of unknown function (DUF1769) Bact_transglu_N PF08379.5 GAM22418.1 - 0.018 15.3 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region DUF3571 PF12095.3 GAM22419.1 - 0.15 12.2 1.6 8.4 6.7 0.0 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3571) DNA_pol_B_2 PF03175.8 GAM22420.1 - 0.0013 17.5 0.7 0.002 16.8 0.2 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ribosomal_L21p PF00829.16 GAM22421.1 - 0.37 10.9 2.7 2.3 8.4 0.2 2.5 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein DUF2018 PF09442.5 GAM22421.1 - 5.2 7.7 6.0 5.5 7.6 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) zf-RING_5 PF14634.1 GAM22422.1 - 0.016 14.8 1.3 0.039 13.6 0.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CGGC PF08821.6 GAM22422.1 - 0.022 14.8 0.6 0.069 13.2 0.4 1.8 2 0 0 2 2 2 0 CGGC domain Toxin-deaminase PF14424.1 GAM22424.1 - 0.027 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases CXCXC PF03128.9 GAM22426.1 - 0.45 10.7 4.2 0.82 9.9 2.9 1.5 1 0 0 1 1 1 0 CXCXC repeat Baculo_11_kDa PF06143.6 GAM22426.1 - 0.48 9.8 3.1 0.79 9.1 2.2 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM173 PF15009.1 GAM22426.1 - 1.1 8.0 3.3 1.2 7.9 2.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 SP_C-Propep PF08999.5 GAM22426.1 - 1.4 8.4 16.2 3 7.3 11.2 1.7 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF454 PF04304.8 GAM22426.1 - 2 8.4 6.5 0.77 9.8 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF454) LMP PF04778.7 GAM22429.1 - 0.077 12.7 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 LMP repeated region ABC_tran PF00005.22 GAM22430.1 - 3.5e-50 169.8 0.0 2.6e-25 89.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 GAM22430.1 - 9.1e-41 140.0 48.9 4.3e-22 78.6 15.8 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 GAM22430.1 - 3.2e-19 69.9 0.0 2.5e-06 27.6 0.0 5.6 5 1 0 5 5 5 2 AAA domain AAA_29 PF13555.1 GAM22430.1 - 3.8e-05 23.1 2.3 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 GAM22430.1 - 0.00019 20.5 0.0 0.21 10.6 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain SMC_N PF02463.14 GAM22430.1 - 0.0016 17.7 0.0 19 4.4 0.0 3.6 2 2 0 4 4 4 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 GAM22430.1 - 0.0017 17.8 0.5 0.97 8.8 0.1 2.7 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 GAM22430.1 - 0.0031 17.3 0.0 0.71 9.8 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAM22430.1 - 0.024 14.9 6.9 0.66 10.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 GAM22430.1 - 0.044 12.9 0.2 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM22430.1 - 0.12 11.7 0.5 3.3 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAM22430.1 - 0.48 10.2 0.5 16 5.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Oxysterol_BP PF01237.13 GAM22431.1 - 4.2e-62 209.7 0.0 5.8e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein FNIP PF05725.7 GAM22432.1 - 9.7e-107 348.7 47.7 7.3e-14 51.4 1.6 13.5 7 4 7 15 15 15 15 FNIP Repeat HlyIII PF03006.15 GAM22433.1 - 1.4e-52 178.2 20.3 1.8e-52 177.9 14.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 GAM22433.1 - 0.021 14.7 0.0 0.088 12.7 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF962) RWP-RK PF02042.10 GAM22434.1 - 5.2e-26 90.2 0.3 1.5e-25 88.7 0.1 1.9 2 0 0 2 2 2 1 RWP-RK domain APG6 PF04111.7 GAM22434.1 - 0.012 14.6 0.3 0.02 13.9 0.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2672 PF10878.3 GAM22434.1 - 0.21 11.3 1.2 0.61 9.8 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Osmo_CC PF08946.5 GAM22434.1 - 7.6 6.6 8.1 3.5 7.7 0.4 3.1 2 1 1 3 3 3 0 Osmosensory transporter coiled coil DUF619 PF04768.8 GAM22435.1 - 2.1e-36 124.8 0.0 5.1e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 GAM22435.1 - 5.7e-06 26.0 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DUF953 PF06110.6 GAM22436.1 - 3e-16 58.9 0.0 3.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 GAM22436.1 - 0.00097 18.7 0.1 0.0019 17.8 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 GAM22436.1 - 0.0035 16.8 0.1 0.0063 16.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 GAM22436.1 - 0.019 14.9 0.0 0.055 13.4 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like Glyco_hydro_38 PF01074.17 GAM22437.1 - 1.9e-64 217.5 5.7 3.1e-64 216.8 4.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM22437.1 - 2.7e-15 56.1 0.0 4.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM22437.1 - 3.9e-15 55.8 0.0 9.2e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain GRAM PF02893.15 GAM22438.1 - 3.5e-07 29.6 0.0 6.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain IncA PF04156.9 GAM22438.1 - 0.35 10.4 9.1 0.67 9.5 6.3 1.5 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 GAM22438.1 - 0.36 11.1 11.9 18 5.7 8.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Atg14 PF10186.4 GAM22438.1 - 2 7.3 9.7 0.32 9.8 3.4 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Alpha-amylase_C PF02806.13 GAM22439.1 - 2.2e-23 82.1 0.1 7e-23 80.5 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 GAM22439.1 - 7.4e-17 61.7 0.2 4.2e-15 55.9 0.1 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 GAM22439.1 - 1.5e-14 53.7 0.1 3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) RuBisCO_large PF00016.15 GAM22439.1 - 0.0078 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RasGAP PF00616.14 GAM22440.1 - 5.6e-44 150.1 2.1 3.6e-43 147.5 0.0 2.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.9 GAM22440.1 - 7.9e-18 64.4 0.0 2.5e-17 62.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DUF3948 PF13134.1 GAM22442.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) DAG1 PF05454.6 GAM22443.1 - 0.012 14.8 1.8 0.013 14.7 1.2 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RRN3 PF05327.6 GAM22443.1 - 0.041 11.9 1.4 0.043 11.9 1.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSDR_N_2 PF13588.1 GAM22443.1 - 0.064 13.0 1.5 0.062 13.1 0.7 1.4 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) MCPVI PF02993.9 GAM22443.1 - 5 7.2 8.2 7.9 6.5 5.7 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Mucin PF01456.12 GAM22444.1 - 1.1 9.0 21.8 2.4 7.9 15.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein WRC PF08879.5 GAM22445.1 - 0.0048 16.5 4.2 0.0048 16.5 2.9 2.4 1 1 1 2 2 2 1 WRC DUF1936 PF09151.5 GAM22445.1 - 0.68 9.4 3.1 11 5.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) IncA PF04156.9 GAM22445.1 - 1 8.8 4.4 1.6 8.2 3.0 1.2 1 0 0 1 1 1 0 IncA protein THDPS_N PF14790.1 GAM22447.1 - 0.091 12.3 2.0 0.18 11.3 0.2 2.3 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal DUF4449 PF14613.1 GAM22448.1 - 3.1e-07 30.4 3.9 6.6e-07 29.3 2.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) Intron_maturas2 PF01348.16 GAM22448.1 - 0.004 17.1 1.9 0.011 15.7 1.3 1.7 1 0 0 1 1 1 1 Type II intron maturase PALP PF00291.20 GAM22449.1 - 3.5e-59 200.5 0.0 1e-58 199.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 GAM22449.1 - 1.9e-16 59.5 0.0 1.1e-10 41.0 0.0 3.0 2 1 0 2 2 2 2 CBS domain HAD PF12710.2 GAM22449.1 - 0.029 14.5 0.1 0.2 11.8 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase RAB3GAP2_N PF14655.1 GAM22450.1 - 0.026 13.5 5.4 0.5 9.3 1.5 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Zn_clus PF00172.13 GAM22450.1 - 0.028 14.3 6.7 0.051 13.4 4.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2547 PF10818.3 GAM22450.1 - 0.04 14.5 0.5 0.04 14.5 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Glyco_hydro_65m PF03632.10 GAM22451.1 - 4.5e-79 265.7 5.2 1e-77 261.3 3.6 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.4 GAM22451.1 - 1.8e-12 46.2 0.0 2e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_63 PF03200.11 GAM22452.1 - 4e-229 762.5 14.0 2.5e-228 759.9 9.7 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase TRAM_LAG1_CLN8 PF03798.11 GAM22453.1 - 6.4e-35 120.5 34.1 6.4e-35 120.5 23.6 1.9 2 0 0 2 2 2 1 TLC domain Tmemb_9 PF05434.6 GAM22453.1 - 0.1 12.3 0.2 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 TMEM9 TIG PF01833.19 GAM22454.1 - 2e-10 40.4 31.9 1e-05 25.4 1.2 4.8 5 1 1 6 6 6 3 IPT/TIG domain EGF_2 PF07974.8 GAM22455.1 - 0.0011 19.1 11.1 0.0021 18.1 7.7 1.5 1 0 0 1 1 1 1 EGF-like domain DUF872 PF05915.7 GAM22455.1 - 0.093 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.3 GAM22455.1 - 0.095 12.7 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) EB PF01683.13 GAM22455.1 - 0.32 11.1 6.1 0.7 10.0 4.2 1.5 1 0 0 1 1 1 0 EB module DUF3534 PF12053.3 GAM22456.1 - 0.0065 16.3 0.1 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3534) Cytokin_check_N PF10407.4 GAM22456.1 - 0.068 12.8 0.1 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus 1-cysPrx_C PF10417.4 GAM22456.1 - 0.11 12.2 0.1 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin SNARE PF05739.14 GAM22457.1 - 1.6e-11 43.6 7.6 2.6e-11 43.0 2.8 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 GAM22457.1 - 1.3e-05 25.2 6.6 1.3e-05 25.2 4.6 2.7 2 1 1 3 3 3 1 Syntaxin LMBR1 PF04791.11 GAM22457.1 - 1.7 7.0 5.1 3.5 6.0 3.5 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein Syntaxin-6_N PF09177.6 GAM22457.1 - 2.7 8.4 8.1 2.1 8.8 1.6 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal RP-C_C PF11800.3 GAM22457.1 - 5.6 6.6 8.5 4.3 6.9 4.2 2.1 1 1 1 3 3 3 0 Replication protein C C-terminal region Kinesin PF00225.18 GAM22458.1 - 2.9e-108 361.5 4.9 2.9e-108 361.5 3.4 3.2 4 1 1 5 5 5 1 Kinesin motor domain Kinesin-relat_1 PF12711.2 GAM22458.1 - 1.7e-07 31.5 4.0 1.7e-07 31.5 2.8 8.3 6 3 1 8 8 8 3 Kinesin motor Response_reg PF00072.19 GAM22459.1 - 1e-20 73.7 0.1 1.6e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain CsgF PF10614.4 GAM22459.1 - 0.02 14.8 2.0 0.028 14.4 1.4 1.2 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein TSA PF03249.8 GAM22459.1 - 4.3 5.7 7.4 5.5 5.4 5.1 1.1 1 0 0 1 1 1 0 Type specific antigen Cyclin PF08613.6 GAM22460.1 - 0.00032 21.1 3.6 0.00068 20.0 2.5 1.8 1 1 0 1 1 1 1 Cyclin DUF3895 PF13034.1 GAM22460.1 - 0.045 13.2 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) Abhydrolase_6 PF12697.2 GAM22461.1 - 4.8e-17 62.6 0.2 1.9e-16 60.6 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM22461.1 - 5.3e-06 26.1 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM22461.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 2.3 3 1 1 4 4 4 1 Alpha/beta hydrolase family PIGA PF08288.7 GAM22461.1 - 0.011 16.0 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) RAM PF15320.1 GAM22461.1 - 0.49 10.6 7.2 1.1 9.5 5.0 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Pro_isomerase PF00160.16 GAM22462.1 - 3.2e-47 160.6 2.9 3.6e-47 160.4 2.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HemN_C PF06969.11 GAM22463.1 - 1.3e-09 38.0 0.1 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM PF04055.16 GAM22463.1 - 2.1e-07 31.2 0.0 4.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Asp PF00026.18 GAM22464.1 - 1.2e-11 44.4 1.9 2.6e-11 43.3 1.3 1.5 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 GAM22464.1 - 2.5e-10 40.1 0.0 7.6e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 GAM22464.1 - 5.9e-09 36.0 2.0 1.4e-08 34.8 1.4 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal CBM49 PF09478.5 GAM22464.1 - 8.2e-09 35.4 2.3 0.00036 20.5 0.2 2.6 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 Asp_protease_2 PF13650.1 GAM22464.1 - 0.054 14.0 0.0 6.9 7.2 0.0 3.2 3 0 0 3 3 3 0 Aspartyl protease Response_reg PF00072.19 GAM22465.1 - 2.1e-18 66.3 0.0 6.7e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain DDE_Tnp_1_7 PF13843.1 GAM22466.1 - 0.00061 18.9 0.0 0.00092 18.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DUF2259 PF10016.4 GAM22467.1 - 0.054 13.2 0.2 0.064 12.9 0.2 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) PAT1 PF09770.4 GAM22467.1 - 1.2 7.2 26.1 1.4 7.1 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VPS9 PF02204.13 GAM22469.1 - 3.8e-07 30.0 0.0 1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Cwf_Cwc_15 PF04889.7 GAM22469.1 - 0.0055 16.4 5.3 0.0055 16.4 3.6 1.9 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein PA14 PF07691.7 GAM22470.1 - 1.8e-10 40.6 0.1 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM22470.1 - 0.0011 18.7 6.1 0.0011 18.7 4.2 13.3 12 2 0 12 12 12 4 Dictyostelium (slime mold) repeat Rabaptin PF03528.10 GAM22472.1 - 0.0028 17.5 0.6 0.0028 17.5 0.4 2.6 1 1 0 2 2 2 1 Rabaptin zf-B_box PF00643.19 GAM22472.1 - 0.011 15.6 2.1 0.031 14.1 1.5 1.8 1 0 0 1 1 1 0 B-box zinc finger PBP1_TM PF14812.1 GAM22472.1 - 0.61 10.4 3.4 1.3 9.4 0.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-Q PF13094.1 GAM22472.1 - 0.94 9.4 13.0 0.93 9.5 4.3 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Kelch_6 PF13964.1 GAM22473.1 - 4.8e-07 29.6 1.4 0.00092 19.2 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 GAM22473.1 - 1.6e-06 27.8 0.8 0.00021 21.0 0.0 3.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22473.1 - 2.3e-06 27.0 2.0 0.088 12.3 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM22473.1 - 0.00023 21.2 0.1 0.0055 16.8 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM22473.1 - 0.0058 16.3 0.9 9.7 6.1 0.0 3.5 3 1 0 3 3 3 2 Kelch motif Terpene_synth PF01397.16 GAM22473.1 - 0.044 13.1 0.1 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain FHA PF00498.21 GAM22474.1 - 9e-12 44.9 0.3 2.2e-11 43.6 0.2 1.7 1 0 0 1 1 1 1 FHA domain Kelch_6 PF13964.1 GAM22475.1 - 8.9e-10 38.3 5.1 5.3e-05 23.1 0.0 4.8 3 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM22475.1 - 9.8e-08 31.6 0.7 6.4e-06 25.8 0.0 3.1 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22475.1 - 1.4e-07 30.9 1.4 9.2e-05 21.9 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM22475.1 - 0.001 19.1 0.0 0.018 15.1 0.0 2.8 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM22475.1 - 0.0055 16.4 1.1 0.052 13.3 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Terpene_synth PF01397.16 GAM22475.1 - 0.0098 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Herpes_UL24 PF01646.11 GAM22476.1 - 0.08 12.3 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Herpes virus protein UL24 Kelch_4 PF13418.1 GAM22477.1 - 1.4e-06 27.9 1.3 0.0064 16.2 0.1 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM22477.1 - 5.2e-05 23.2 8.0 0.0055 16.8 0.0 3.5 3 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM22477.1 - 0.00097 19.2 0.3 0.14 12.3 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22477.1 - 0.18 11.3 0.1 0.18 11.3 0.1 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 GAM22478.1 - 1.9e-05 24.6 4.0 0.1 12.8 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM22478.1 - 5.4e-05 22.8 5.5 0.0029 17.3 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22478.1 - 0.00045 19.7 2.1 0.31 10.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif FliT PF05400.8 GAM22478.1 - 0.0022 18.3 1.9 0.45 10.9 0.1 2.3 2 0 0 2 2 2 2 Flagellar protein FliT Kelch_5 PF13854.1 GAM22478.1 - 0.0055 16.6 3.1 0.8 9.7 0.1 2.8 3 0 0 3 3 2 2 Kelch motif Gp-FAR-1 PF05823.7 GAM22478.1 - 0.007 16.3 0.9 0.087 12.7 0.0 2.2 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Kelch_2 PF07646.10 GAM22478.1 - 0.0081 15.8 2.1 4.6 7.1 0.0 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM22478.1 - 0.0084 16.2 1.3 1.1 9.5 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Baculo_PEP_C PF04513.7 GAM22478.1 - 0.0096 15.7 0.5 0.0096 15.7 0.3 2.3 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus EF1_GNE PF00736.14 GAM22478.1 - 0.055 13.1 1.5 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain ArsC PF03960.10 GAM22478.1 - 0.12 12.4 2.0 7.4 6.6 0.2 2.4 2 0 0 2 2 2 0 ArsC family Snapin_Pallidin PF14712.1 GAM22478.1 - 1.2 9.4 11.2 0.27 11.5 1.6 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF1664 PF07889.7 GAM22478.1 - 1.7 8.4 8.7 0.15 11.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Z1 PF10593.4 GAM22478.1 - 3.5 6.7 7.8 0.43 9.7 1.2 2.0 1 1 1 2 2 2 0 Z1 domain Med22 PF06179.7 GAM22478.1 - 7.3 6.6 12.4 9.8e+02 -0.2 8.6 2.3 1 1 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex PQ-loop PF04193.9 GAM22479.1 - 8.5e-39 130.9 19.5 1.7e-20 72.3 5.5 3.1 3 0 0 3 3 3 2 PQ loop repeat DDE_Tnp_4 PF13359.1 GAM22480.1 - 6.7e-16 58.2 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM22480.1 - 4.4e-07 29.6 0.2 2.5e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain PA14 PF07691.7 GAM22481.1 - 9.2e-14 51.3 0.1 1.7e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM22481.1 - 0.0011 18.7 5.3 0.0011 18.7 3.7 12.1 12 1 0 12 12 12 3 Dictyostelium (slime mold) repeat DUF367 PF04034.8 GAM22482.1 - 4e-50 168.6 0.0 6e-50 168.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 GAM22482.1 - 2.6e-13 49.2 0.0 5.7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CENP-T PF15511.1 GAM22482.1 - 0.59 9.3 33.3 1.2 8.3 23.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 GAM22482.1 - 4.1 6.3 51.0 7.9 5.4 35.3 1.5 1 0 0 1 1 1 0 BUD22 Cation_efflux PF01545.16 GAM22483.1 - 7e-69 232.0 0.1 8.6e-69 231.7 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 GAM22483.1 - 0.00066 18.7 32.2 0.25 10.3 8.8 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter DUF3188 PF11384.3 GAM22483.1 - 3.1 7.4 6.0 13 5.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) PPR_2 PF13041.1 GAM22484.1 - 2.4e-22 78.6 0.0 7.6e-08 32.2 0.0 4.4 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.1 GAM22484.1 - 1.3e-21 75.0 1.7 3.1e-07 30.1 0.0 6.6 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 GAM22484.1 - 2.3e-20 71.0 1.0 5.6e-06 25.9 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 GAM22484.1 - 4.1e-15 54.9 0.1 6.1e-06 25.6 0.0 5.9 6 0 0 6 6 6 3 PPR repeat TPR_14 PF13428.1 GAM22484.1 - 0.038 14.6 0.0 47 5.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Ran_BP1 PF00638.13 GAM22485.1 - 3.8e-15 55.9 0.1 9.6e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 RanBP1 domain Dicty_CTDC PF00526.13 GAM22486.1 - 1.6e-65 216.1 179.4 7.4e-11 41.6 6.8 12.8 11 2 0 12 12 12 11 Dictyostelium (slime mold) repeat CBM_2 PF00553.14 GAM22487.1 - 2.9 7.9 7.6 4 7.5 5.0 1.3 1 1 0 1 1 1 0 Cellulose binding domain DUF1649 PF07855.7 GAM22488.1 - 3.2e-40 137.4 3.5 3.8e-40 137.2 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Coiled PF05710.7 GAM22489.1 - 6.7 7.2 31.8 28 5.2 22.1 2.3 1 1 0 1 1 1 0 Coiled coil AAA_22 PF13401.1 GAM22490.1 - 2.3e-05 24.5 0.0 1.2 9.3 0.0 5.6 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 GAM22490.1 - 0.00011 22.4 2.0 0.097 12.8 0.0 4.6 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAM22490.1 - 0.0022 17.4 0.1 1.1 8.7 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_16 PF13191.1 GAM22490.1 - 0.069 13.1 0.6 28 4.6 0.0 4.1 4 0 0 4 4 4 0 AAA ATPase domain AAA_25 PF13481.1 GAM22490.1 - 0.49 9.7 0.0 15 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM22490.1 - 1.5 8.6 0.3 79 3.1 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain DUF1206 PF06724.6 GAM22491.1 - 4.7e-15 55.1 18.4 4.4e-07 29.5 0.5 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF912 PF06024.7 GAM22491.1 - 0.61 10.1 0.1 0.61 10.1 0.0 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) XPA_C PF05181.7 GAM22492.1 - 0.0054 16.2 0.5 0.013 15.0 0.4 1.7 1 1 0 1 1 1 1 XPA protein C-terminus AAA PF00004.24 GAM22494.1 - 7.8e-09 35.8 2.2 5.7e-05 23.3 0.0 4.3 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) UCH PF00443.24 GAM22494.1 - 6.6e-08 31.9 0.1 6.6e-07 28.7 0.1 2.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA_22 PF13401.1 GAM22494.1 - 3.1e-07 30.5 0.3 1.3 9.1 0.0 6.5 8 0 0 8 8 8 2 AAA domain T2SE PF00437.15 GAM22494.1 - 0.00066 18.6 0.0 0.32 9.8 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_16 PF13191.1 GAM22494.1 - 0.00068 19.6 0.0 1.9 8.4 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.12 GAM22494.1 - 0.00074 18.9 0.0 0.36 10.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 GAM22494.1 - 0.055 13.2 0.0 8.3 6.2 0.0 3.6 4 0 0 4 4 4 0 Part of AAA domain AAA_30 PF13604.1 GAM22494.1 - 0.082 12.4 0.0 8.9 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 GAM22494.1 - 0.092 12.1 0.0 6.8 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 GAM22495.1 - 4.3e-27 94.2 6.3 9.5e-09 35.4 0.2 4.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22495.1 - 2.5e-24 85.1 10.4 3.5e-06 27.3 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) RGS PF00615.14 GAM22495.1 - 4.7e-23 81.5 0.4 1.6e-17 63.6 0.0 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain Ank PF00023.25 GAM22495.1 - 4.3e-22 76.7 6.6 7.8e-05 22.2 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 GAM22495.1 - 5.3e-21 74.1 4.2 5.9e-07 29.5 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22495.1 - 6.5e-21 72.3 4.9 0.00041 20.3 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Plasmod_dom_1 PF09715.5 GAM22495.1 - 0.0085 15.9 0.3 5.6 6.9 0.0 3.0 2 0 0 2 2 2 2 Plasmodium protein of unknown function (Plasmod_dom_1) FNIP PF05725.7 GAM22496.1 - 6.3e-25 86.8 0.6 3.9e-10 39.5 0.0 5.7 6 0 0 6 6 6 3 FNIP Repeat DUF2141 PF09912.4 GAM22498.1 - 1.8e-05 24.3 3.4 1.1 8.8 0.1 7.6 8 0 0 8 8 8 1 Uncharacterized protein conserved in bacteria (DUF2141) Phage_FRD3 PF05798.6 GAM22498.1 - 0.0003 21.0 0.4 36 4.7 0.0 5.6 6 0 0 6 6 6 0 Bacteriophage FRD3 protein Glyco_hydro_32C PF08244.7 GAM22498.1 - 0.0085 16.4 0.4 24 5.3 0.1 4.8 5 1 0 5 5 5 1 Glycosyl hydrolases family 32 C terminal Kunitz_BPTI PF00014.18 GAM22498.1 - 0.033 14.3 2.1 8.2 6.7 0.1 4.6 6 0 0 6 6 6 0 Kunitz/Bovine pancreatic trypsin inhibitor domain DUF1312 PF07009.6 GAM22498.1 - 0.046 13.5 0.3 16 5.3 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1312) TraL PF07178.6 GAM22499.1 - 5.1 7.1 5.3 1.9 8.5 1.9 1.6 1 1 1 2 2 2 0 TraL protein Abhydrolase_9_N PF15420.1 GAM22500.1 - 3.4 7.3 6.7 3.7 7.2 4.6 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus MIF4G PF02854.14 GAM22501.1 - 9.2e-05 21.9 0.9 0.00026 20.4 0.4 1.9 1 1 0 1 1 1 1 MIF4G domain Spt20 PF12090.3 GAM22503.1 - 0.0018 17.6 14.8 0.0018 17.6 10.2 1.4 2 0 0 2 2 2 1 Spt20 family Tfb4 PF03850.9 GAM22503.1 - 0.058 12.6 3.7 0.058 12.6 2.5 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 PAT1 PF09770.4 GAM22503.1 - 0.51 8.5 36.0 0.57 8.3 24.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 GAM22503.1 - 0.98 7.0 28.0 1.3 6.5 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3708 PF12501.3 GAM22503.1 - 3.7 7.3 4.9 8 6.2 3.4 1.5 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Pox_Ag35 PF03286.9 GAM22504.1 - 0.0087 15.6 6.5 0.0087 15.6 4.5 4.1 3 1 0 3 3 3 1 Pox virus Ag35 surface protein TINF2_N PF14973.1 GAM22504.1 - 0.013 15.6 0.2 0.013 15.6 0.1 2.4 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Ank_5 PF13857.1 GAM22506.1 - 2.6e-10 40.1 1.7 0.00041 20.4 0.1 4.6 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM22506.1 - 6.7e-10 39.2 0.6 0.00058 20.2 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM22506.1 - 3.2e-09 36.9 0.6 8.8e-08 32.3 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22506.1 - 0.00011 22.1 3.9 9.2 6.8 0.0 5.3 5 1 2 7 7 7 3 Ankyrin repeat Ank PF00023.25 GAM22506.1 - 0.00021 20.9 0.3 8.3 6.4 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeat Psb28 PF03912.9 GAM22506.1 - 0.093 12.7 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Psb28 protein Defensin_propep PF00879.13 GAM22507.1 - 0.14 12.1 0.5 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 Defensin propeptide Pentapeptide_4 PF13599.1 GAM22507.1 - 0.36 10.6 3.8 2 8.3 2.7 2.0 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) WAP PF00095.16 GAM22507.1 - 6.1 6.9 33.3 0.59 10.1 8.7 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' ADH_N PF08240.7 GAM22508.1 - 1.8e-29 101.7 4.4 3e-29 100.9 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM22508.1 - 3.2e-17 62.2 0.1 1e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 GAM22508.1 - 0.005 16.4 0.1 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 GAM22508.1 - 0.0066 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAM22508.1 - 0.012 15.1 0.2 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.14 GAM22508.1 - 0.013 14.1 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase ADH_zinc_N_2 PF13602.1 GAM22508.1 - 0.089 13.6 0.0 0.24 12.3 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Alpha_L_fucos PF01120.12 GAM22509.1 - 5.6e-52 176.7 0.6 7e-52 176.4 0.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Imm-NTF2-2 PF15631.1 GAM22509.1 - 0.071 13.1 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein FAD-oxidase_C PF02913.14 GAM22510.1 - 6.1e-55 186.2 0.0 7.8e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM22510.1 - 2.6e-38 130.6 0.3 4.4e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain CH PF00307.26 GAM22511.1 - 3.1e-67 223.4 3.1 1.1e-21 76.9 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM22511.1 - 5.9e-12 45.0 0.7 0.00012 21.6 0.0 3.7 4 0 0 4 4 4 3 CAMSAP CH domain DNA_pol_viral_N PF00242.12 GAM22513.1 - 0.13 11.2 10.0 0.18 10.8 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TFIIF_alpha PF05793.7 GAM22513.1 - 0.57 8.4 12.4 0.85 7.9 8.6 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 GAM22513.1 - 1.4 9.2 12.2 1.8 8.9 3.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank_2 PF12796.2 GAM22514.1 - 1.6e-08 34.8 10.9 0.14 12.5 0.1 7.0 6 2 1 7 7 7 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22514.1 - 0.013 15.6 12.0 58 4.3 0.0 9.2 12 0 0 12 12 12 0 Ankyrin repeat DUF1937 PF09152.5 GAM22514.1 - 0.023 15.2 0.1 0.06 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) Ank_2 PF12796.2 GAM22515.1 - 4.5e-11 42.9 2.8 0.015 15.6 0.0 6.6 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22515.1 - 9.8e-08 32.3 2.6 0.024 15.1 0.0 6.9 9 0 0 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22515.1 - 8.4e-07 28.6 7.3 25 5.5 0.0 9.7 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.1 GAM22515.1 - 1.4e-06 28.3 6.6 2.1 8.7 0.0 7.5 8 1 0 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM22515.1 - 0.029 14.1 1.5 81 3.3 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.2 GAM22516.1 - 1.9e-05 24.8 0.0 0.012 15.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Luciferase_N PF05295.6 GAM22516.1 - 0.012 15.3 0.2 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Serglycin PF04360.7 GAM22517.1 - 0.031 14.0 0.7 0.047 13.4 0.5 1.3 1 0 0 1 1 1 0 Serglycin CBS PF00571.23 GAM22518.1 - 0.0044 16.7 0.2 0.0057 16.4 0.1 1.4 1 1 0 1 1 1 1 CBS domain Mso1_Sec1_bdg PF14475.1 GAM22518.1 - 0.1 12.0 0.9 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Homoserine_dh PF00742.14 GAM22519.1 - 1.9e-48 164.5 0.0 4.2e-48 163.3 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase AA_kinase PF00696.23 GAM22519.1 - 1.4e-42 145.9 0.0 1.1e-41 142.9 0.0 2.2 2 0 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.11 GAM22519.1 - 7.8e-16 58.5 0.0 2.4e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.1 GAM22519.1 - 6.6e-09 35.1 7.1 1.1e-06 28.0 0.2 3.0 3 0 0 3 3 3 2 ACT domain ACT PF01842.20 GAM22519.1 - 1.2e-08 34.1 1.7 4.8e-07 29.1 0.1 2.8 2 0 0 2 2 2 1 ACT domain Semialdhyde_dh PF01118.19 GAM22519.1 - 0.035 14.3 0.2 0.57 10.4 0.1 2.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CorA PF01544.13 GAM22520.1 - 1.4e-54 185.1 4.1 1.9e-54 184.7 2.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Colicin_V PF02674.11 GAM22520.1 - 0.019 14.8 0.4 0.085 12.7 0.1 2.0 2 0 0 2 2 2 0 Colicin V production protein DnaJ PF00226.26 GAM22521.1 - 2.9e-19 68.5 0.1 4.7e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 GAM22521.1 - 3.5e-13 49.0 0.7 0.0035 17.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 GAM22522.1 - 1.7e-16 60.2 1.1 0.00043 20.5 0.0 8.0 6 2 2 8 8 8 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22522.1 - 8.3e-08 32.5 8.0 0.59 10.7 0.0 9.0 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM22522.1 - 3.2e-06 26.6 1.5 12 5.9 0.0 7.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.1 GAM22522.1 - 2.6e-05 24.0 17.5 16 6.0 0.0 11.5 12 0 0 12 12 12 1 Ankyrin repeat Nop14 PF04147.7 GAM22522.1 - 0.065 11.1 11.8 0.12 10.2 8.2 1.3 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 GAM22522.1 - 0.17 10.9 10.4 0.35 9.9 7.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 GAM22522.1 - 0.86 7.5 11.4 2.3 6.1 7.9 1.6 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 GAM22522.1 - 4.9 5.5 17.3 8 4.8 12.0 1.2 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 GAM22522.1 - 7 4.7 5.7 14 3.7 3.9 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF4645 PF15488.1 GAM22523.1 - 0.06 12.4 0.1 0.065 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) DSPc PF00782.15 GAM22524.1 - 1.1e-29 102.7 0.0 1.8e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM22524.1 - 0.00018 20.9 0.1 0.00057 19.3 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM22524.1 - 0.0077 16.4 0.4 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM22524.1 - 0.041 13.9 0.7 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Metallothio_2 PF01439.13 GAM22524.1 - 0.1 13.1 9.1 0.98 10.0 0.2 3.3 2 2 1 3 3 3 0 Metallothionein Pyr_redox PF00070.22 GAM22525.1 - 1.8e-19 69.8 0.9 2.7e-10 40.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM22525.1 - 5.1e-18 65.6 0.0 6.2e-17 62.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM22525.1 - 5.1e-09 36.4 0.0 0.048 13.7 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM22525.1 - 4.9e-05 22.3 0.1 0.15 10.9 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 GAM22525.1 - 8.6e-05 21.6 0.0 0.068 12.0 0.0 2.3 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM22525.1 - 0.00011 21.9 0.0 1.7 8.4 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 GAM22525.1 - 0.0015 17.2 0.2 0.023 13.3 0.0 2.5 2 1 1 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 GAM22525.1 - 0.0058 15.5 0.1 0.39 9.5 0.0 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAM22525.1 - 0.0077 15.3 0.3 0.03 13.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 GAM22525.1 - 0.011 15.7 0.3 0.34 10.9 0.0 2.8 2 1 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 GAM22525.1 - 0.014 13.8 0.0 0.074 11.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 GAM22525.1 - 0.016 15.2 0.0 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 GAM22525.1 - 0.036 14.3 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.12 GAM22525.1 - 0.05 12.6 0.2 0.59 9.1 0.0 2.4 2 1 0 2 2 2 0 Thi4 family ThiF PF00899.16 GAM22525.1 - 0.12 12.2 0.6 11 5.8 0.0 2.9 3 0 0 3 3 3 0 ThiF family Adap_comp_sub PF00928.16 GAM22527.1 - 6.4e-22 77.9 0.1 1e-21 77.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM22527.1 - 0.0013 18.4 0.2 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GRP PF07172.6 GAM22527.1 - 0.13 12.6 17.6 0.24 11.8 12.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family PH PF00169.24 GAM22528.1 - 4.2e-11 42.9 0.4 4.2e-11 42.9 0.3 2.6 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 GAM22528.1 - 0.00067 19.6 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 GAM22528.1 - 0.0049 17.0 7.4 0.0072 16.5 0.7 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain Lung_7-TM_R PF06814.8 GAM22529.1 - 8.7e-13 47.8 17.4 2.8e-12 46.2 12.0 1.7 1 1 0 1 1 1 1 Lung seven transmembrane receptor Pro-kuma_activ PF09286.6 GAM22530.1 - 7.3e-29 100.6 0.0 1.6e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM22530.1 - 5.6e-05 22.4 0.7 0.0001 21.5 0.5 1.3 1 0 0 1 1 1 1 Subtilase family Lipase_3 PF01764.20 GAM22531.1 - 8e-30 103.3 0.0 1.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM22531.1 - 1.3e-05 24.7 0.2 3.5e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAM22531.1 - 0.0049 16.6 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM22531.1 - 0.0091 15.8 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM22531.1 - 0.052 13.1 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ion_trans_2 PF07885.11 GAM22531.1 - 0.087 12.5 2.4 0.31 10.7 0.2 2.4 2 0 0 2 2 2 0 Ion channel Abhydrolase_3 PF07859.8 GAM22531.1 - 0.091 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acyltransferase PF01553.16 GAM22532.1 - 2.4e-14 52.8 0.0 3.8e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.27 GAM22533.1 - 5.3e-44 146.5 21.0 5.2e-07 29.3 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM22533.1 - 0.061 12.0 0.4 1.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like PQ-loop PF04193.9 GAM22534.1 - 3e-20 71.5 14.3 1.8e-12 46.5 3.1 4.1 4 1 1 5 5 5 2 PQ loop repeat UBN2_2 PF14227.1 GAM22534.1 - 0.04 13.4 0.3 3.9 7.0 0.0 2.7 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type DUF347 PF03988.7 GAM22534.1 - 0.049 13.5 2.8 4.8 7.1 0.1 3.4 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) YwiC PF14256.1 GAM22534.1 - 0.069 13.2 0.3 0.069 13.2 0.2 2.2 2 0 0 2 2 2 0 YwiC-like protein Syndecan PF01034.15 GAM22534.1 - 0.16 11.6 0.6 3 7.5 0.0 2.7 2 0 0 2 2 2 0 Syndecan domain DUF2116 PF09889.4 GAM22534.1 - 0.65 9.8 2.5 0.72 9.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4231 PF14015.1 GAM22534.1 - 0.66 9.9 8.9 0.36 10.8 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) MtN3_slv PF03083.11 GAM22534.1 - 2.6 7.9 26.8 0.13 12.1 6.0 3.8 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange DUF2663 PF10864.3 GAM22534.1 - 3.7 7.7 7.9 1.5 9.0 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2663) PAP2 PF01569.16 GAM22535.1 - 9e-09 35.0 6.0 9e-09 35.0 4.2 2.7 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 GAM22535.1 - 6.8e-06 25.7 3.3 6.8e-06 25.7 2.3 2.1 2 0 0 2 2 2 1 PAP2 superfamily Rpp20 PF12328.3 GAM22536.1 - 2.1 8.0 0.0 2.1 8.0 0.0 3.6 3 1 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P RabGAP-TBC PF00566.13 GAM22537.1 - 4e-43 147.3 5.0 4e-43 147.3 3.4 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mucin PF01456.12 GAM22537.1 - 0.009 15.7 29.2 1.2 8.8 0.0 2.6 2 1 0 2 2 2 2 Mucin-like glycoprotein BAF1_ABF1 PF04684.8 GAM22537.1 - 0.032 13.0 9.8 0.059 12.2 6.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.4 GAM22537.1 - 0.17 10.4 17.8 0.076 11.6 8.4 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein TFIIA PF03153.8 GAM22537.1 - 0.37 10.6 29.0 0.068 13.0 10.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 GAM22537.1 - 5 5.4 25.7 0.042 12.3 8.8 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Ras PF00071.17 GAM22538.1 - 1.9e-58 196.4 0.6 2.3e-58 196.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM22538.1 - 4.1e-19 69.2 0.1 8.1e-19 68.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM22538.1 - 1.3e-14 53.8 0.1 1.6e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM22538.1 - 4.2e-10 39.3 0.1 5.2e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM22538.1 - 4.4e-08 32.5 0.2 5.7e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM22538.1 - 8.1e-05 22.5 0.0 0.00029 20.7 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM22538.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM22538.1 - 0.036 13.4 0.0 0.19 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM22538.1 - 0.078 12.6 0.1 0.36 10.4 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase ETF PF01012.16 GAM22539.1 - 2.3e-38 131.5 0.7 3.1e-38 131.0 0.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPP_enzyme_M PF00205.17 GAM22539.1 - 0.024 14.3 0.4 0.16 11.7 0.0 2.2 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Dynamin_M PF01031.15 GAM22540.1 - 4.6e-107 357.1 2.5 8.2e-107 356.3 1.7 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 GAM22540.1 - 9.4e-58 194.7 0.0 9.4e-58 194.7 0.0 3.1 3 1 0 3 3 3 1 Dynamin family GED PF02212.13 GAM22540.1 - 5.5e-34 115.9 2.3 1.9e-33 114.2 1.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAM22540.1 - 0.00011 22.1 0.0 0.00053 19.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Baculo_p74 PF04583.7 GAM22540.1 - 0.0087 15.2 0.1 3.3 6.8 0.0 2.5 2 0 0 2 2 2 2 Baculoviridae p74 conserved region Miro PF08477.8 GAM22540.1 - 0.0092 16.4 0.0 0.036 14.5 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein DUF2076 PF09849.4 GAM22540.1 - 2.7 7.9 32.5 0.31 11.0 10.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.4 GAM22540.1 - 3.1 5.9 40.6 4.4 5.4 28.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CH PF00307.26 GAM22541.1 - 1.4e-11 44.3 0.0 3.9e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain RhoGEF PF00621.15 GAM22541.1 - 5.9e-09 36.0 0.1 2.7e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM22541.1 - 9.4e-08 32.2 0.4 4.3e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 PH domain CAMSAP_CH PF11971.3 GAM22541.1 - 0.034 13.7 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain DUF479 PF04336.7 GAM22541.1 - 0.057 13.5 1.6 0.071 13.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF479 DUF4011 PF13195.1 GAM22541.1 - 5.5 6.9 7.8 3 7.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) IBR PF01485.16 GAM22542.1 - 2.4e-10 40.1 60.1 1.3e-06 28.2 5.4 5.2 3 1 1 4 4 4 3 IBR domain RWD PF05773.17 GAM22542.1 - 3.4e-07 30.1 0.3 1.3e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 RWD domain zf-C3HC4_2 PF13923.1 GAM22542.1 - 0.00011 22.0 7.2 0.00011 22.0 5.0 5.4 5 2 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM22542.1 - 0.0002 21.1 21.8 0.00033 20.4 6.2 4.6 4 0 0 4 4 4 2 Ring finger domain zf-RING_5 PF14634.1 GAM22542.1 - 0.0003 20.4 8.8 0.0003 20.4 6.1 5.1 4 1 1 5 5 5 1 zinc-RING finger domain Hexapep PF00132.19 GAM22543.1 - 3.1e-10 39.0 9.1 2.6e-05 23.5 0.0 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM22543.1 - 1.3e-05 24.6 0.2 0.026 14.0 0.0 2.8 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase NSs PF11073.3 GAM22543.1 - 0.0073 15.5 0.2 2.4 7.3 0.0 2.1 2 0 0 2 2 2 2 Rift valley fever virus non structural protein (NSs) like RNA_pol_Rpb8 PF03870.10 GAM22544.1 - 6.2e-45 152.7 0.3 6.9e-45 152.6 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Lipase_3 PF01764.20 GAM22545.1 - 3.9e-19 68.6 0.0 1.1e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.2 GAM22545.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sigma70_ner PF04546.8 GAM22545.1 - 0.17 11.4 3.6 16 5.0 2.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region TIG PF01833.19 GAM22546.1 - 1.3e-49 166.1 224.3 5.9e-08 32.6 4.3 19.1 16 4 3 19 19 19 16 IPT/TIG domain DUF2217 PF10265.4 GAM22548.1 - 0.48 9.1 6.5 0.77 8.4 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 GAM22548.1 - 0.97 7.6 15.4 1.4 7.1 10.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF159 PF02586.9 GAM22549.1 - 3.2e-21 75.8 0.0 4.3e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Gly-rich_Ago1 PF12764.2 GAM22549.1 - 0.17 12.5 0.4 0.17 12.5 0.3 2.3 2 1 0 2 2 2 0 Glycine-rich region of argonaut Macoilin PF09726.4 GAM22550.1 - 0.39 8.9 13.3 0.44 8.7 9.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 GAM22550.1 - 4.5 6.5 22.5 5.3 6.3 15.6 1.1 1 0 0 1 1 1 0 Vta1 like XPG_N PF00752.12 GAM22551.1 - 1.4e-08 34.8 0.1 1.5e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 GAM22551.1 - 7.9e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing FMN_red PF03358.10 GAM22552.1 - 4.5e-29 100.9 0.0 5.7e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM22552.1 - 1.4e-05 24.7 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Prefoldin_2 PF01920.15 GAM22553.1 - 1e-19 70.2 14.2 1e-19 70.2 9.8 2.2 1 1 1 2 2 2 1 Prefoldin subunit DUF695 PF05117.7 GAM22553.1 - 0.049 13.5 5.8 1.6 8.6 0.3 2.6 1 1 0 2 2 2 0 Family of unknown function (DUF695) Prefoldin_3 PF13758.1 GAM22553.1 - 0.13 12.0 9.4 0.024 14.3 4.2 1.6 2 0 0 2 2 2 0 Prefoldin subunit COG2 PF06148.6 GAM22553.1 - 0.31 10.9 11.7 1.3 8.9 1.5 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2584 PF10763.4 GAM22553.1 - 0.43 10.4 2.9 0.32 10.8 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2584) Tropomyosin_1 PF12718.2 GAM22553.1 - 0.55 10.0 21.2 0.27 11.0 4.8 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF501 PF04417.7 GAM22553.1 - 1.1 9.1 4.7 6.9 6.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) Mnd1 PF03962.10 GAM22553.1 - 1.3 8.6 16.0 0.17 11.5 4.7 2.0 1 1 1 2 2 2 0 Mnd1 family DUF607 PF04678.8 GAM22553.1 - 2.4 8.0 6.0 2.4 8.0 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 CDC37_N PF03234.9 GAM22553.1 - 3 8.1 11.3 3.5 7.9 7.8 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF2730 PF10805.3 GAM22553.1 - 3.1 7.5 9.3 0.7 9.6 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ATP-synt_B PF00430.13 GAM22553.1 - 4.7 7.0 21.6 0.57 9.9 5.9 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) IncA PF04156.9 GAM22553.1 - 5.5 6.5 20.7 19 4.8 14.3 1.7 1 1 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 GAM22554.1 - 1.7e-91 307.0 39.5 6.5e-91 305.1 27.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM22554.1 - 1.1e-27 96.6 43.4 4.2e-18 65.1 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 GAM22554.1 - 0.045 13.7 0.6 0.16 11.9 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) TIMELESS PF04821.9 GAM22555.1 - 9.2e-26 90.6 9.2 9.2e-26 90.6 6.3 3.0 2 1 0 2 2 2 1 Timeless protein RRM_5 PF13893.1 GAM22556.1 - 4.2e-10 39.3 0.0 1.4e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM22556.1 - 6.1e-10 38.6 0.1 1.2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22556.1 - 3.2e-05 23.8 0.0 0.0052 16.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 GAM22556.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Ank_2 PF12796.2 GAM22557.1 - 3.8e-08 33.5 4.2 0.0015 18.8 0.0 5.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22557.1 - 6.2e-06 25.9 1.6 1.2e+02 3.4 0.0 7.8 8 0 0 8 8 8 0 Ankyrin repeat Ank PF00023.25 GAM22557.1 - 0.00014 21.4 0.3 13 5.7 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAM22557.1 - 0.0071 16.8 0.5 1.6e+02 2.9 0.0 5.7 6 2 1 7 7 7 0 Ankyrin repeats (many copies) KbaA PF14089.1 GAM22557.1 - 0.025 14.1 0.1 0.14 11.6 0.0 2.1 1 1 0 1 1 1 0 KinB-signalling pathway activation in sporulation DUF1411 PF07199.6 GAM22558.1 - 0.12 11.7 0.2 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) Excalibur PF05901.6 GAM22558.1 - 2.3 8.6 5.8 1.2e+02 3.1 4.0 3.0 1 1 0 1 1 1 0 Excalibur calcium-binding domain Kelch_6 PF13964.1 GAM22560.1 - 1e-11 44.4 9.8 0.00013 21.9 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM22560.1 - 1.4e-11 43.9 0.6 6.4e-05 22.6 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain zf-B_box PF00643.19 GAM22560.1 - 3e-06 27.0 8.2 3e-06 27.0 5.7 1.9 2 0 0 2 2 2 1 B-box zinc finger Kelch_1 PF01344.20 GAM22560.1 - 0.0001 21.7 6.2 0.028 13.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM22560.1 - 0.00034 20.6 0.2 0.2 11.8 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain DUF948 PF06103.6 GAM22560.1 - 0.0084 15.9 0.4 0.042 13.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Kelch_2 PF07646.10 GAM22560.1 - 0.03 14.1 1.7 52 3.8 0.0 3.9 3 0 0 3 3 3 0 Kelch motif LBR_tudor PF09465.5 GAM22560.1 - 0.095 12.3 0.1 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Kelch_5 PF13854.1 GAM22560.1 - 1.8 8.5 15.5 0.2 11.6 0.4 4.4 5 0 0 5 5 5 0 Kelch motif DUF2419 PF10343.4 GAM22561.1 - 4e-88 295.3 0.0 6e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1688 PF07958.6 GAM22561.1 - 0.0028 16.2 0.0 0.25 9.8 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1688) DUF1617 PF07761.7 GAM22561.1 - 0.025 14.6 0.2 0.051 13.6 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1617) Lipase_3 PF01764.20 GAM22562.1 - 1.3e-26 92.8 0.0 1.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 GAM22562.1 - 0.0055 16.3 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 GAM22562.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) TFIIB PF00382.14 GAM22563.1 - 6.5e-26 89.9 0.1 2.3e-15 56.1 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 GAM22563.1 - 1.8e-10 39.9 1.3 3.3e-10 39.1 0.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 GAM22563.1 - 0.0011 18.9 0.0 0.68 9.8 0.0 2.5 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.1 GAM22563.1 - 0.0084 15.2 0.1 0.024 13.7 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Yopt PF09467.5 GAM22563.1 - 0.014 15.1 1.8 0.061 13.1 0.0 2.7 3 0 0 3 3 3 0 Hypothetical protein Yopt DUF3514 PF12027.3 GAM22563.1 - 0.039 13.1 0.5 0.082 12.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) HTH_23 PF13384.1 GAM22563.1 - 0.11 12.1 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Skp1_POZ PF03931.10 GAM22564.1 - 6.9e-08 32.4 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 GAM22564.1 - 0.00074 19.4 1.3 0.0017 18.3 0.1 1.9 1 1 1 2 2 2 1 BTB/POZ domain Aminotran_5 PF00266.14 GAM22565.1 - 1.2e-13 50.5 0.0 1.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_5 PF12695.2 GAM22565.1 - 0.025 14.3 0.0 0.054 13.2 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM22565.1 - 0.092 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 GAM22566.1 - 3.9e-94 315.5 0.0 4.5e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 GAM22566.1 - 0.00028 20.8 0.1 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Beta_elim_lyase PF01212.16 GAM22566.1 - 0.053 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AAA_19 PF13245.1 GAM22566.1 - 0.093 12.4 0.3 0.58 9.9 0.1 2.3 2 1 0 2 2 2 0 Part of AAA domain Glyco_hydro_38 PF01074.17 GAM22567.1 - 2e-37 128.9 0.3 2e-37 128.9 0.2 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 N-terminal domain Elf1 PF05129.8 GAM22568.1 - 2.4e-29 100.8 2.3 2.9e-29 100.6 1.6 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 GAM22568.1 - 0.007 16.6 1.0 0.01 16.1 0.7 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Bcl-2_BAD PF10514.4 GAM22568.1 - 0.024 14.6 0.0 0.028 14.3 0.0 1.0 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD Ribosomal_L37ae PF01780.14 GAM22568.1 - 0.1 12.4 1.2 0.15 11.9 0.8 1.4 1 1 0 1 1 1 0 Ribosomal L37ae protein family Cys_rich_CPXG PF14255.1 GAM22568.1 - 0.24 11.2 4.3 0.22 11.3 2.4 1.4 1 1 0 1 1 1 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.2 GAM22568.1 - 1.5 8.7 4.6 4.2 7.2 3.2 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 GAM22568.1 - 5.6 6.5 8.2 58 3.2 5.6 2.2 1 1 0 1 1 1 0 InsA N-terminal domain FNIP PF05725.7 GAM22569.1 - 1.2e-64 213.9 30.1 4.1e-16 58.6 1.5 8.6 4 2 4 9 9 9 9 FNIP Repeat DUF845 PF05820.6 GAM22569.1 - 0.19 11.4 0.0 2.9 7.6 0.0 2.8 3 1 1 4 4 4 0 Baculovirus protein of unknown function (DUF845) Ribosomal_S15 PF00312.17 GAM22570.1 - 2.8e-18 65.4 0.0 3.4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 HicB PF05534.7 GAM22570.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 HicB family G-alpha PF00503.15 GAM22571.1 - 1.4e-56 191.9 15.0 1.7e-56 191.5 10.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM22571.1 - 4.3e-07 29.3 0.0 1.1e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family zf-C3HC PF07967.8 GAM22572.1 - 3.5e-31 107.7 2.2 2.9e-28 98.3 0.0 3.4 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 GAM22572.1 - 3.2e-11 42.9 10.2 9.5e-07 28.5 0.2 4.4 3 2 0 3 3 3 2 Rsm1-like DUF3740 PF12548.3 GAM22572.1 - 0.038 14.2 0.2 0.038 14.2 0.1 2.8 3 0 0 3 3 3 0 Sulfatase protein BIR PF00653.16 GAM22572.1 - 0.19 12.1 2.4 13 6.2 0.1 2.9 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Ribosomal_S26e PF01283.14 GAM22573.1 - 1.1e-45 154.5 8.4 1.2e-45 154.4 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF2602 PF10782.4 GAM22573.1 - 0.18 11.6 1.8 0.53 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2602) Fer4_7 PF12838.2 GAM22573.1 - 0.7 10.3 4.7 6.2 7.2 3.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAM22573.1 - 1.3 8.8 6.0 2 8.2 1.4 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF1660 PF07874.6 GAM22573.1 - 8.3 6.7 5.9 19 5.6 0.6 2.1 1 1 1 2 2 2 0 Prophage protein (DUF1660) Ribosomal_L19e PF01280.15 GAM22574.1 - 4.4e-28 97.9 9.2 1.6e-18 66.9 0.0 2.9 2 1 1 3 3 3 2 Ribosomal protein L19e Mur_ligase_M PF08245.7 GAM22574.1 - 0.027 14.5 0.3 0.038 14.0 0.2 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Phe_tRNA-synt_N PF02912.13 GAM22575.1 - 0.092 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Glyco_hydro_38 PF01074.17 GAM22576.1 - 5.1e-66 222.7 0.9 5.1e-66 222.7 0.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM22576.1 - 5.9e-30 104.4 0.1 1.1e-29 103.5 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM22576.1 - 2.8e-17 62.6 0.7 5.7e-17 61.7 0.5 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain DUF2392 PF10288.4 GAM22576.1 - 0.044 14.1 0.9 66 3.9 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2392) MIT PF04212.13 GAM22577.1 - 5.8e-11 42.1 1.9 1.3e-10 41.0 1.3 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 GAM22577.1 - 0.012 15.2 4.4 0.025 14.2 3.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 GAM22577.1 - 0.026 14.4 0.6 0.026 14.4 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ECH PF00378.15 GAM22577.1 - 0.041 12.9 0.0 0.092 11.8 0.0 1.5 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family TPR_1 PF00515.23 GAM22577.1 - 0.13 11.8 0.7 0.39 10.3 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2857 PF11198.3 GAM22578.1 - 0.03 13.8 0.1 0.036 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) Ank_3 PF13606.1 GAM22579.1 - 2.3e-05 24.2 0.2 1.8 9.0 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 GAM22579.1 - 0.0015 18.8 0.2 0.023 15.0 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22579.1 - 0.029 14.8 1.9 8.6 7.0 0.2 3.2 1 1 3 4 4 4 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM22580.1 - 4.4e-05 23.8 0.1 0.00012 22.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM22580.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM22580.1 - 0.0063 16.2 0.1 3.8 7.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 GAM22580.1 - 0.051 13.8 0.0 0.42 10.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 GAM22580.1 - 0.065 13.5 0.2 4 7.8 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Pkinase PF00069.20 GAM22581.1 - 7.6e-56 189.1 0.0 1.3e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22581.1 - 1.8e-35 122.2 0.0 3e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22581.1 - 3.8e-05 22.8 0.0 9.7e-05 21.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM22581.1 - 0.024 13.7 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_BLRF2 PF05812.7 GAM22582.1 - 0.011 15.5 0.2 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein EF-hand_2 PF09068.6 GAM22582.1 - 0.03 14.3 0.3 0.042 13.9 0.2 1.2 1 0 0 1 1 1 0 EF hand Apis_Csd PF11671.3 GAM22582.1 - 0.19 11.5 8.9 0.27 11.0 6.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein T4SS PF07996.6 GAM22582.1 - 0.35 10.6 4.5 0.56 10.0 3.1 1.4 1 1 0 1 1 1 0 Type IV secretion system proteins DUF972 PF06156.8 GAM22582.1 - 2.2 8.6 8.7 27 5.1 6.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) M_domain PF12938.2 GAM22582.1 - 3.9 7.1 7.0 6.7 6.4 4.6 1.5 1 1 1 2 2 2 0 M domain of GW182 PI3Ka PF00613.15 GAM22583.1 - 1.7e-58 196.8 1.2 2.8e-58 196.1 0.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM22583.1 - 3.2e-48 164.2 0.0 7.4e-48 163.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM22583.1 - 6e-24 84.4 0.0 1.5e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 GAM22583.1 - 3e-14 52.8 1.3 2.3e-09 37.1 0.0 3.5 3 0 0 3 3 3 2 PI3-kinase family, ras-binding domain HEAT_2 PF13646.1 GAM22583.1 - 0.0041 17.3 0.0 0.06 13.6 0.0 2.4 2 0 0 2 2 2 1 HEAT repeats WD40 PF00400.27 GAM22584.1 - 1.4e-78 256.1 27.7 2.9e-11 42.8 0.1 10.2 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.6 GAM22584.1 - 7e-41 139.1 3.1 1.5e-40 138.1 2.2 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 GAM22584.1 - 2e-13 49.3 16.7 6.7e-05 21.2 0.1 6.9 2 2 5 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM22584.1 - 1.6e-07 30.4 20.0 0.11 11.2 0.4 8.1 2 2 5 7 7 7 7 Nup133 N terminal like YmzC PF14157.1 GAM22584.1 - 0.0012 18.5 0.3 1.8 8.4 0.2 4.1 3 0 0 3 3 3 2 YmzC-like protein Thioredoxin_2 PF13098.1 GAM22585.1 - 0.0086 16.2 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain CENP-B_dimeris PF09026.5 GAM22585.1 - 0.023 14.9 2.7 0.067 13.4 1.9 1.8 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_A24 PF01478.13 GAM22586.1 - 0.48 10.6 10.3 0.46 10.6 2.7 2.4 2 1 0 2 2 2 0 Type IV leader peptidase family TBCC PF07986.7 GAM22587.1 - 1.3e-24 85.9 10.1 2.3e-24 85.0 7.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 GAM22587.1 - 0.97 8.7 11.5 0.038 13.3 3.9 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal NUDIX PF00293.23 GAM22588.1 - 4.1e-11 42.6 0.0 4.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Seipin PF06775.9 GAM22589.1 - 3.4e-46 157.2 0.9 3.4e-46 157.2 0.6 1.4 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DIOX_N PF14226.1 GAM22591.1 - 2.3e-07 31.3 0.0 4.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM22591.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TH1 PF04858.8 GAM22593.1 - 7.3e-80 268.7 3.3 2.5e-54 184.4 0.2 3.0 1 1 2 3 3 3 3 TH1 protein TH1 PF04858.8 GAM22594.1 - 4e-27 94.6 0.0 4.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 TH1 protein PRCC PF10253.4 GAM22594.1 - 0.85 10.2 12.9 1.1 9.8 8.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF566 PF04484.7 GAM22594.1 - 1.9 7.9 12.3 2.1 7.8 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) CytochromB561_N PF09786.4 GAM22594.1 - 2.6 6.3 11.0 3 6.2 7.6 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal SRP-alpha_N PF04086.8 GAM22594.1 - 5.1 6.3 8.9 6.1 6.1 6.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.4 GAM22594.1 - 8.8 4.4 8.4 9.3 4.3 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_C39_2 PF13529.1 GAM22595.1 - 0.00038 20.8 0.4 0.00088 19.6 0.3 1.7 1 0 0 1 1 1 1 Peptidase_C39 like family DUF4405 PF14358.1 GAM22595.1 - 0.0022 18.0 0.1 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) Vps26 PF03643.10 GAM22595.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 ApoL PF05461.6 GAM22596.1 - 4.6e-05 22.8 1.5 6.1e-05 22.4 1.1 1.2 1 0 0 1 1 1 1 Apolipoprotein L PRD_Mga PF08270.6 GAM22596.1 - 0.0003 20.1 0.3 0.0014 17.9 0.1 1.9 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) PRD domain zf-RING_2 PF13639.1 GAM22596.1 - 0.019 14.8 3.9 0.042 13.6 2.7 1.6 1 0 0 1 1 1 0 Ring finger domain U-box PF04564.10 GAM22596.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain Herpes_glycop PF01528.11 GAM22596.1 - 0.061 12.0 0.2 0.061 12.0 0.1 1.5 2 0 0 2 2 2 0 Herpesvirus glycoprotein M priB_priC PF07445.7 GAM22596.1 - 0.079 12.4 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Primosomal replication protein priB and priC zf-C3HC4_2 PF13923.1 GAM22596.1 - 0.12 12.4 3.9 0.12 12.4 1.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.7 GAM22597.1 - 1.5e-56 188.0 33.3 9e-09 35.1 0.0 12.8 4 3 8 13 13 13 11 FNIP Repeat tRNA-synt_1e PF01406.14 GAM22599.1 - 8.1e-114 379.7 0.1 1.5e-113 378.9 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAM22599.1 - 1.7e-08 33.5 0.5 8.1e-05 21.4 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM22599.1 - 0.0038 15.3 0.0 0.011 13.7 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 GAM22599.1 - 0.0066 15.1 1.3 0.0085 14.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain FNIP PF05725.7 GAM22600.1 - 5e-52 173.6 47.2 1.3e-16 60.2 0.2 8.9 3 2 8 11 11 11 11 FNIP Repeat TPR_12 PF13424.1 GAM22601.1 - 7e-11 41.9 4.6 2e-05 24.4 2.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM22601.1 - 1.7e-08 33.5 3.9 9.8e-06 24.7 0.3 3.0 3 0 0 3 3 3 2 SHNi-TPR TPR_2 PF07719.12 GAM22601.1 - 1.9e-06 27.3 2.3 0.0051 16.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM22601.1 - 7.5e-05 22.3 3.3 0.00012 21.6 1.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 GAM22601.1 - 9.4e-05 21.9 4.9 0.22 11.4 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM22601.1 - 0.0072 15.9 5.8 1.1 8.9 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM22601.1 - 0.0099 16.0 3.7 0.95 9.6 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Mucin PF01456.12 GAM22601.1 - 0.011 15.4 7.1 0.011 15.4 4.9 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2225 PF09986.4 GAM22601.1 - 0.013 14.9 1.6 0.023 14.1 0.6 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF2762 PF10960.3 GAM22601.1 - 0.019 14.6 0.1 0.076 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Dicty_REP PF05086.7 GAM22601.1 - 4.4 4.9 15.7 0.081 10.6 0.2 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Alba PF01918.16 GAM22602.1 - 9e-09 34.8 0.1 1.6e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Alba NAC PF01849.13 GAM22603.1 - 2.3e-17 62.2 0.1 5.7e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 NAC domain DUF3606 PF12244.3 GAM22603.1 - 0.054 13.1 0.2 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) hGDE_central PF14702.1 GAM22603.1 - 0.068 12.3 0.9 0.1 11.7 0.6 1.2 1 0 0 1 1 1 0 central domain of human glycogen debranching enzyme Mucin PF01456.12 GAM22603.1 - 0.86 9.3 17.2 0.54 10.0 7.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Aminotran_1_2 PF00155.16 GAM22604.1 - 2.3e-83 280.1 0.0 2.6e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 GAM22605.1 - 2.9e-24 84.0 14.8 2e-09 36.9 0.1 6.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM22605.1 - 1.4e-05 24.8 0.1 3.1 7.5 0.0 4.1 3 1 0 3 3 3 3 Ciliary BBSome complex subunit 2, middle region TFIIA PF03153.8 GAM22605.1 - 0.41 10.5 15.4 0.6 9.9 10.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.7 GAM22606.1 - 1.2e-94 310.0 12.2 5.3e-17 61.4 0.0 10.5 4 3 2 11 11 11 11 FNIP Repeat E1-E2_ATPase PF00122.15 GAM22607.1 - 1.9e-50 171.0 0.5 4.9e-50 169.7 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 GAM22607.1 - 2.6e-49 168.5 0.2 6.9e-49 167.1 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAM22607.1 - 2.6e-22 78.7 11.6 1.1e-10 41.4 0.0 4.0 4 0 0 4 4 4 2 Heavy-metal-associated domain HAD PF12710.2 GAM22607.1 - 3e-17 63.3 0.0 5.3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM22607.1 - 0.001 18.7 7.9 0.036 13.6 0.0 4.3 3 2 1 4 4 4 2 haloacid dehalogenase-like hydrolase Vpu PF00558.14 GAM22608.1 - 0.049 13.1 2.0 0.086 12.4 1.4 1.4 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.8 GAM22608.1 - 0.07 13.3 12.3 0.13 12.4 8.5 1.5 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 GAM22609.1 - 0.0013 18.6 1.7 0.0013 18.6 1.2 3.2 4 0 0 4 4 4 1 IPT/TIG domain Cadherin-like PF12733.2 GAM22609.1 - 0.051 13.8 11.3 0.96 9.7 0.1 4.0 3 2 2 5 5 5 0 Cadherin-like beta sandwich domain EGF_2 PF07974.8 GAM22609.1 - 0.086 13.0 11.9 0.15 12.2 8.2 1.4 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM22609.1 - 0.16 11.9 8.3 0.32 11.0 5.8 1.5 1 0 0 1 1 1 0 EGF-like domain YchF-GTPase_C PF06071.8 GAM22612.1 - 2.8e-33 113.5 0.2 7.1e-33 112.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 GAM22612.1 - 3.1e-19 69.0 0.1 8.1e-19 67.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM22612.1 - 1.1e-06 28.0 0.0 2.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 GAM22612.1 - 0.02 14.8 0.0 0.053 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 GAM22612.1 - 0.021 13.6 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 GAM22612.1 - 0.033 13.3 0.0 0.071 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Filamin PF00630.14 GAM22613.1 - 6.1e-127 415.1 11.2 1.4e-23 83.3 0.1 6.2 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.26 GAM22613.1 - 7.3e-34 116.0 0.3 4.7e-17 61.9 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Big_1 PF02369.11 GAM22613.1 - 1.3e-12 47.4 7.2 0.13 12.1 0.0 6.4 6 0 0 6 6 6 4 Bacterial Ig-like domain (group 1) Y_Y_Y PF07495.8 GAM22613.1 - 1.4e-09 37.5 2.0 0.25 11.1 0.0 5.8 5 0 0 5 5 5 4 Y_Y_Y domain YtkA PF13115.1 GAM22613.1 - 2e-08 34.4 7.8 0.22 11.8 0.0 6.2 6 0 0 6 6 6 3 YtkA-like CAMSAP_CH PF11971.3 GAM22613.1 - 2.2e-07 30.4 0.0 0.0029 17.1 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Big_3_4 PF13754.1 GAM22613.1 - 0.00081 19.6 32.0 0.012 15.9 0.8 8.0 7 1 1 8 8 8 2 Bacterial Ig-like domain (group 3) Neurexophilin PF06312.7 GAM22613.1 - 0.038 13.2 3.8 71 2.5 0.0 4.9 5 1 0 6 6 6 0 Neurexophilin FlgD_ig PF13860.1 GAM22613.1 - 1.5 8.6 14.9 31 4.3 0.0 6.4 6 2 2 8 8 8 0 FlgD Ig-like domain He_PIG PF05345.7 GAM22613.1 - 6 6.9 24.7 5.7 7.0 0.2 7.2 8 1 0 8 8 8 0 Putative Ig domain CAF-1_p150 PF11600.3 GAM22615.1 - 0.00097 18.5 5.3 0.0012 18.2 3.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Dicty_REP PF05086.7 GAM22615.1 - 0.0041 14.9 7.3 0.0044 14.8 5.0 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 GAM22615.1 - 0.14 11.8 19.0 0.17 11.6 13.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Sporozoite_P67 PF05642.6 GAM22615.1 - 0.39 8.5 7.7 0.47 8.2 5.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 GAM22615.1 - 0.5 8.2 21.7 0.6 8.0 15.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4105 PF13387.1 GAM22615.1 - 1.4 8.0 5.5 6.4 5.9 3.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4105) Paramyxo_C PF01692.13 GAM22615.1 - 1.7 8.1 6.4 2.1 7.9 4.5 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c IncA PF04156.9 GAM22615.1 - 2.3 7.7 6.0 3.1 7.3 4.2 1.1 1 0 0 1 1 1 0 IncA protein PRCC PF10253.4 GAM22615.1 - 2.5 8.7 10.6 3.3 8.3 7.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SprA-related PF12118.3 GAM22615.1 - 3.5 6.8 10.4 4.2 6.6 7.2 1.1 1 0 0 1 1 1 0 SprA-related family Tcp11 PF05794.8 GAM22616.1 - 9.5 4.7 7.4 15 4.1 5.1 1.3 1 0 0 1 1 1 0 T-complex protein 11 rve PF00665.21 GAM22618.1 - 2.4e-06 27.6 0.1 3.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain DUF2141 PF09912.4 GAM22619.1 - 0.027 14.1 2.6 2.3 7.9 0.1 4.0 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) Histone PF00125.19 GAM22621.1 - 4.3e-30 103.6 0.7 7.9e-30 102.7 0.5 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM22621.1 - 1.5e-05 25.0 0.1 3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 GAM22621.1 - 0.033 13.4 1.2 0.04 13.1 0.9 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 GAM22621.1 - 0.034 13.9 0.1 0.082 12.6 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Metallophos PF00149.23 GAM22622.1 - 1.1e-17 64.0 8.1 2.3e-17 63.0 5.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM22622.1 - 1.5e-16 60.1 0.3 3.8e-16 58.9 0.2 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAM22622.1 - 1.4e-06 27.2 0.1 2.9e-06 26.1 0.1 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAM22622.1 - 1.5e-06 28.1 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-RING_2 PF13639.1 GAM22623.1 - 1.3e-09 37.6 8.5 1.3e-09 37.6 5.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 GAM22623.1 - 3.9e-09 36.0 10.1 9.5e-09 34.7 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM22623.1 - 7e-08 32.3 9.6 7e-08 32.3 6.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM22623.1 - 5.2e-07 29.6 4.8 1.4e-06 28.3 3.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAM22623.1 - 4.1e-06 26.3 7.1 4.1e-06 26.3 4.9 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM22623.1 - 0.00012 21.7 9.0 0.00032 20.3 6.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAM22623.1 - 0.0036 17.1 9.2 0.0091 15.8 6.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RNA_pol_3_Rpc31 PF11705.3 GAM22623.1 - 0.0064 16.4 2.2 0.0064 16.4 1.5 6.9 5 1 2 7 7 4 1 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_6 PF14835.1 GAM22623.1 - 0.0082 15.8 2.5 0.016 14.9 1.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 GAM22623.1 - 0.03 13.8 3.8 0.083 12.4 2.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 GAM22623.1 - 0.032 13.7 7.8 0.057 12.9 5.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 GAM22623.1 - 0.034 13.9 2.9 0.07 12.9 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAM22623.1 - 0.055 13.1 5.5 0.17 11.6 3.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 GAM22623.1 - 4.2 7.0 13.8 0.13 11.8 4.8 2.2 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Clat_adaptor_s PF01217.15 GAM22624.1 - 6.4e-57 191.2 0.7 7e-57 191.1 0.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF879 PF05947.7 GAM22624.1 - 0.13 10.5 0.0 0.15 10.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) 6PF2K PF01591.13 GAM22625.1 - 3.1e-80 268.4 0.0 4.3e-80 267.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 GAM22625.1 - 7.3e-33 113.8 0.0 1.1e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 GAM22625.1 - 7e-07 29.2 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM22625.1 - 7.8e-05 23.4 0.0 0.0024 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM22625.1 - 0.044 12.8 0.0 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 GAM22625.1 - 0.1 12.7 0.0 0.49 10.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FNIP PF05725.7 GAM22626.1 - 1e-21 76.5 4.4 1.7e-06 27.8 0.0 6.0 5 2 1 6 6 6 4 FNIP Repeat MFS_1 PF07690.11 GAM22627.1 - 2.8e-29 101.9 20.4 7.1e-28 97.3 3.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 GAM22627.1 - 8.4e-18 63.7 4.4 1.3e-16 59.8 0.2 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 GAM22627.1 - 2.5e-10 39.3 15.7 3.6e-06 25.6 1.0 2.3 2 1 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 GAM22627.1 - 0.00018 20.1 1.3 0.00018 20.1 0.9 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Ank_2 PF12796.2 GAM22628.1 - 3.1e-08 33.8 0.3 0.00038 20.7 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22628.1 - 7.6e-07 28.7 0.2 1.3 9.4 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 GAM22628.1 - 1.1e-05 25.5 0.0 1.7 8.9 0.0 4.6 3 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM22628.1 - 7.7e-05 23.1 0.2 1.9 9.0 0.1 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM22628.1 - 0.00015 21.4 0.9 4.3 7.3 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.2 GAM22629.1 - 0.00014 22.1 0.5 0.027 14.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22629.1 - 0.042 14.0 1.7 22 5.6 0.1 4.3 4 0 0 4 4 4 0 Ankyrin repeat SWIRM PF04433.12 GAM22631.1 - 1.5e-21 76.3 0.2 3.5e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAM22631.1 - 3.4e-05 23.7 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM22631.1 - 0.0003 20.8 0.1 0.00088 19.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain p450 PF00067.17 GAM22632.1 - 9.8e-83 278.2 0.1 3e-61 207.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Chitin_synth_2 PF03142.10 GAM22632.1 - 0.076 11.3 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase Es2 PF09751.4 GAM22633.1 - 4.7e-44 151.4 7.2 8.2e-44 150.6 5.0 1.4 1 0 0 1 1 1 1 Nuclear protein Es2 EXS PF03124.9 GAM22634.1 - 1.4e-92 310.4 22.8 1.9e-92 309.9 15.8 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAM22634.1 - 8.7e-21 74.9 9.7 3.7e-12 46.6 0.9 3.2 2 1 1 3 3 3 3 SPX domain DUF3627 PF12299.3 GAM22634.1 - 0.058 13.4 0.2 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) Metallophos PF00149.23 GAM22636.1 - 1.1e-11 44.5 0.9 1.8e-11 43.8 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_B PF00136.16 GAM22637.1 - 5.7e-90 302.3 1.2 1.1e-89 301.3 0.9 1.4 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAM22637.1 - 3e-21 75.6 0.8 6e-10 38.4 0.1 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 GAM22637.1 - 6.7e-14 51.6 6.2 1.8e-13 50.2 4.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Homeobox PF00046.24 GAM22638.1 - 0.0003 20.3 0.5 0.0024 17.4 0.7 2.3 2 0 0 2 2 2 1 Homeobox domain SMP_2 PF10144.4 GAM22639.1 - 0.0074 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence factor haemolysin Pkinase_Tyr PF07714.12 GAM22640.1 - 8.6e-51 172.4 0.0 1.5e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM22640.1 - 3.3e-40 137.8 0.0 7.5e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 GAM22640.1 - 4.3e-13 48.5 5.0 8.7e-08 31.6 0.1 6.8 3 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM22640.1 - 1.7e-12 46.9 25.8 1.6e-09 37.3 0.6 4.7 3 1 1 4 4 4 2 Leucine rich repeat Miro PF08477.8 GAM22640.1 - 3.8e-11 43.5 0.2 9.3e-09 35.8 0.2 2.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM22640.1 - 5.1e-10 38.9 0.0 1.1e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Ras family LRR_1 PF00560.28 GAM22640.1 - 1.3e-08 33.6 17.2 0.62 10.3 0.0 8.3 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 GAM22640.1 - 9.1e-06 25.0 18.4 0.28 11.5 0.1 8.0 9 0 0 9 9 7 2 Leucine rich repeat Arf PF00025.16 GAM22640.1 - 0.00035 19.8 0.0 0.016 14.4 0.0 2.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM22640.1 - 0.0012 18.7 0.1 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM22640.1 - 0.014 15.5 0.2 0.039 14.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 GAM22640.1 - 0.018 14.0 0.5 0.031 13.3 0.3 1.3 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 GAM22640.1 - 0.02 13.6 0.5 0.037 12.7 0.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MobB PF03205.9 GAM22640.1 - 0.022 14.4 0.3 0.046 13.4 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LRR_6 PF13516.1 GAM22640.1 - 0.026 14.5 22.7 33 4.9 0.0 8.5 9 0 0 9 9 8 0 Leucine Rich repeat Arch_ATPase PF01637.13 GAM22640.1 - 0.061 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase TraK PF06586.6 GAM22641.1 - 0.003 16.7 0.4 0.0032 16.6 0.3 1.2 1 0 0 1 1 1 1 TraK protein Cytochrom_NNT PF03264.9 GAM22641.1 - 0.0034 16.8 0.4 0.0042 16.5 0.3 1.1 1 0 0 1 1 1 1 NapC/NirT cytochrome c family, N-terminal region Nop52 PF05997.7 GAM22642.1 - 3e-36 124.9 0.8 3e-36 124.9 0.5 1.9 2 0 0 2 2 2 1 Nucleolar protein,Nop52 Nop14 PF04147.7 GAM22642.1 - 0.0014 16.6 11.5 0.0018 16.2 8.0 1.2 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 GAM22642.1 - 0.0066 16.0 11.0 0.011 15.3 7.6 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region Prothymosin PF03247.9 GAM22642.1 - 0.023 14.8 19.1 0.037 14.1 13.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Dicty_REP PF05086.7 GAM22642.1 - 0.034 11.9 7.8 0.056 11.2 5.4 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNase_H2-Ydr279 PF09468.5 GAM22642.1 - 0.078 12.1 5.5 0.11 11.6 2.2 1.9 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RRN3 PF05327.6 GAM22642.1 - 0.16 10.0 4.5 0.26 9.3 3.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 GAM22642.1 - 0.22 11.5 15.5 0.42 10.6 10.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ebola_NP PF05505.7 GAM22642.1 - 0.22 9.5 7.2 0.27 9.2 5.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein SDA1 PF05285.7 GAM22642.1 - 0.26 10.5 13.4 0.39 9.9 9.3 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 GAM22642.1 - 0.4 9.3 13.1 0.55 8.8 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.8 GAM22642.1 - 0.96 7.1 15.1 1.4 6.6 10.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 GAM22642.1 - 1.3 6.9 7.7 1.8 6.4 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 GAM22642.1 - 1.4 8.5 14.9 2.1 7.8 10.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.7 GAM22642.1 - 3.8 6.6 9.0 5.3 6.2 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 GAM22643.1 - 7.3e-34 114.4 6.9 2.2e-08 33.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 GAM22643.1 - 0.031 13.9 0.2 1.4 8.6 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2158 PF09926.4 GAM22643.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) DUF4291 PF14124.1 GAM22644.1 - 6.8e-71 237.6 6.8 7.7e-71 237.4 4.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Nop PF01798.13 GAM22645.1 - 1.2e-35 122.0 0.6 2.1e-35 121.2 0.1 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 GAM22645.1 - 3.7e-26 91.9 3.7 1e-25 90.5 2.6 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 GAM22645.1 - 1.1e-17 63.5 2.8 1.1e-17 63.5 0.3 2.3 2 0 0 2 2 2 1 NOSIC (NUC001) domain Ank_2 PF12796.2 GAM22646.1 - 2.6e-20 72.5 3.5 1.2e-06 28.7 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22646.1 - 5.2e-19 68.2 4.7 5.3e-05 23.6 0.1 5.5 4 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22646.1 - 1.4e-18 66.5 6.4 0.0005 20.2 0.0 5.8 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22646.1 - 5.1e-15 54.0 5.7 0.097 12.9 0.0 6.7 5 2 3 8 8 8 4 Ankyrin repeat Ank PF00023.25 GAM22646.1 - 3.2e-12 45.5 2.2 0.11 12.3 0.1 6.3 6 1 1 7 7 7 4 Ankyrin repeat Sushi_2 PF09014.5 GAM22646.1 - 0.02 14.6 0.3 0.54 10.0 0.1 2.6 2 1 1 3 3 3 0 Beta-2-glycoprotein-1 fifth domain DUF1843 PF08898.5 GAM22646.1 - 0.024 14.6 0.9 7 6.7 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Rbsn PF11464.3 GAM22646.1 - 0.032 13.8 1.0 42 3.8 0.0 4.4 5 0 0 5 5 5 0 Rabenosyn Rab binding domain PepX_N PF09168.5 GAM22646.1 - 0.056 13.6 0.2 28 4.9 0.0 3.2 2 1 2 4 4 4 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Kunitz_BPTI PF00014.18 GAM22646.1 - 1.8 8.8 6.8 19 5.5 0.1 4.0 2 1 3 5 5 5 0 Kunitz/Bovine pancreatic trypsin inhibitor domain EnY2 PF10163.4 GAM22647.1 - 6.2e-29 99.7 0.4 7.5e-29 99.4 0.3 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 Trans_reg_C PF00486.23 GAM22647.1 - 0.05 13.5 0.1 0.59 10.0 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Beta-lactamase PF00144.19 GAM22647.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase Kelch_4 PF13418.1 GAM22648.1 - 1.9e-05 24.3 0.3 0.017 14.8 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM22648.1 - 0.00033 20.6 0.1 0.079 13.1 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.1 GAM22648.1 - 0.0017 18.4 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM22648.1 - 0.0026 17.6 0.1 0.0074 16.2 0.1 1.8 1 0 0 1 1 1 1 Kelch motif Kelch_2 PF07646.10 GAM22648.1 - 0.0056 16.4 0.1 0.25 11.1 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 GAM22648.1 - 0.067 12.7 0.6 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 GAM22649.1 - 6.7e-08 32.4 0.7 2.7e-05 24.1 0.0 2.5 2 1 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22649.1 - 8.5e-08 31.6 0.1 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 GAM22649.1 - 3.4e-07 30.0 1.9 0.0057 16.5 0.1 2.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 GAM22649.1 - 1.9e-06 27.5 0.0 0.0088 15.7 0.0 2.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM22649.1 - 7.3e-06 25.9 1.1 0.021 14.9 0.0 2.8 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM22649.1 - 0.022 14.5 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Rax2 PF12768.2 GAM22649.1 - 0.073 12.2 0.0 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 Cortical protein marker for cell polarity Ribosomal_L35Ae PF01247.13 GAM22650.1 - 2.9e-35 119.8 0.3 3.3e-35 119.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 GAM22650.1 - 0.056 13.3 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain WD40 PF00400.27 GAM22651.1 - 8.2e-15 54.0 17.4 8.5e-05 22.2 0.1 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat Sec16_C PF12931.2 GAM22651.1 - 5e-10 39.5 0.1 2.6e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 GAM22651.1 - 0.02 14.7 0.1 0.02 14.7 0.1 2.3 2 1 0 2 2 2 0 Prp18 domain LVIVD PF08309.6 GAM22651.1 - 0.15 11.0 2.2 0.23 10.4 0.1 2.4 3 0 0 3 3 3 0 LVIVD repeat CBM49 PF09478.5 GAM22652.1 - 1.1e-17 63.9 0.2 1.4e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 GST_N PF02798.15 GAM22653.1 - 1.4e-12 47.5 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM22653.1 - 1.5e-08 35.0 0.0 1.9e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM22653.1 - 9.9e-07 28.6 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM22653.1 - 0.00053 20.1 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM22653.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.24 GAM22654.1 - 4.3e-44 149.9 1.3 2.9e-43 147.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM22654.1 - 3.7e-27 94.0 0.4 3e-26 91.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Ribosomal_60s PF00428.14 GAM22654.1 - 0.016 15.6 0.1 0.052 13.9 0.1 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Helicase_C_2 PF13307.1 GAM22654.1 - 0.055 13.4 0.1 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain Senescence_reg PF04520.8 GAM22654.1 - 0.28 11.6 4.5 0.51 10.8 3.1 1.4 1 0 0 1 1 1 0 Senescence regulator Copine PF07002.11 GAM22655.1 - 5.3e-43 146.2 0.0 2.3e-42 144.1 0.0 1.9 2 0 0 2 2 2 1 Copine C2 PF00168.25 GAM22655.1 - 6.7e-24 83.5 0.2 4e-12 45.8 0.1 2.6 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 GAM22655.1 - 7.1e-11 42.3 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus Glyco_transf_22 PF03901.12 GAM22656.1 - 2.7e-101 339.6 37.0 3.3e-101 339.3 25.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2368 PF10166.4 GAM22656.1 - 0.24 11.0 1.8 0.62 9.6 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) PAT1 PF09770.4 GAM22657.1 - 0.39 8.9 42.7 0.48 8.5 29.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YfhO PF09586.5 GAM22657.1 - 0.61 8.0 27.9 0.7 7.8 19.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF966 PF06136.8 GAM22657.1 - 0.66 9.3 19.9 0.85 8.9 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 GAM22657.1 - 0.98 7.6 23.2 1.1 7.4 16.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 GAM22657.1 - 5.3 5.2 26.7 6.9 4.8 18.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 Acetyltransf_2 PF00797.12 GAM22657.1 - 5.6 6.4 15.0 3.9 6.9 5.3 2.2 2 0 0 2 2 2 0 N-acetyltransferase LicD PF04991.8 GAM22657.1 - 6.2 6.8 20.2 20 5.1 14.0 1.7 1 1 0 1 1 1 0 LicD family UCH PF00443.24 GAM22658.1 - 3.1e-59 200.3 8.3 3.1e-59 200.3 5.7 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAM22658.1 - 2.4e-16 59.5 21.8 2.4e-16 59.5 15.1 3.8 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 GAM22658.1 - 4.1e-15 56.0 19.1 5.1e-14 52.4 5.0 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PGA2 PF07543.7 GAM22658.1 - 0.4 10.4 6.0 22 4.8 3.3 2.9 3 0 0 3 3 3 0 Protein trafficking PGA2 AMMECR1 PF01871.12 GAM22659.1 - 7.5e-48 161.8 0.0 9.1e-48 161.6 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 CBS PF00571.23 GAM22660.1 - 8.9e-10 38.2 0.8 0.00022 20.9 0.1 2.4 2 0 0 2 2 2 2 CBS domain DHHA1 PF02272.14 GAM22660.1 - 0.00019 21.0 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 DHHA1 domain Gln-synt_C PF00120.19 GAM22661.1 - 1.5e-64 217.7 0.0 1.8e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain ubiquitin PF00240.18 GAM22662.1 - 3.1e-09 36.1 0.2 5.8e-09 35.2 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 GAM22662.1 - 4.8e-07 29.3 0.2 1.8e-06 27.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM22662.1 - 6.7e-05 23.0 0.1 0.00019 21.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain USP7_ICP0_bdg PF12436.3 GAM22662.1 - 0.037 13.2 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.3 GAM22662.1 - 0.056 13.7 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TOBE_2 PF08402.5 GAM22662.1 - 0.065 13.2 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 TOBE domain FeoA PF04023.9 GAM22662.1 - 0.073 13.0 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 FeoA domain USP7_C2 PF14533.1 GAM22662.1 - 0.11 11.8 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Porphobil_deam PF01379.15 GAM22663.1 - 2e-86 288.3 0.0 2.5e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 GAM22663.1 - 4.1e-21 74.8 0.1 7.8e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain YxiJ PF14176.1 GAM22663.1 - 0.097 12.7 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 YxiJ-like protein S-methyl_trans PF02574.11 GAM22664.1 - 1.5e-96 323.2 0.0 2.9e-96 322.3 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 GAM22664.1 - 2.3e-73 245.8 0.4 4.8e-73 244.8 0.0 1.7 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 GAM22664.1 - 7.5e-43 146.3 1.9 2.7e-42 144.5 0.6 2.4 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.12 GAM22664.1 - 1.3e-19 70.0 0.1 6.6e-19 67.7 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 GAM22664.1 - 2e-18 66.4 0.7 2.2e-17 63.0 0.2 2.8 3 0 0 3 3 3 1 B12 binding domain OKR_DC_1_N PF03709.10 GAM22664.1 - 0.015 15.3 0.0 1.2 9.1 0.0 3.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF3981 PF13139.1 GAM22665.1 - 0.06 13.3 0.7 0.29 11.1 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3981) SNF2_N PF00176.18 GAM22666.1 - 3e-53 180.5 0.1 4.6e-52 176.6 0.1 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM22666.1 - 1.8e-09 37.2 2.1 2.5e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WD40 PF00400.27 GAM22668.1 - 1e-25 88.5 7.0 4.7e-06 26.2 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 GAM22668.1 - 1.1e-13 51.3 0.4 5.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 GAM22668.1 - 0.047 11.9 0.0 0.11 10.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3312) GAPT PF11770.3 GAM22669.1 - 8.9 5.9 7.0 22 4.6 4.8 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) ArfGap PF01412.13 GAM22670.1 - 8.7e-43 144.8 0.2 8.7e-43 144.8 0.1 3.0 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DDE_3 PF13358.1 GAM22672.1 - 6.4e-20 71.3 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.12 GAM22672.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Codanin-1_C PF15296.1 GAM22672.1 - 0.085 12.7 0.1 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Codanin-1 C-terminus TFIIF_alpha PF05793.7 GAM22673.1 - 0.087 11.1 0.2 0.11 10.7 0.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_holin_4 PF05105.7 GAM22673.1 - 0.13 11.9 0.2 0.56 9.8 0.1 1.9 2 0 0 2 2 2 0 Holin family BNR PF02012.15 GAM22674.1 - 5e-09 34.6 8.7 0.25 11.2 0.0 6.2 5 0 0 5 5 5 4 BNR/Asp-box repeat PH PF00169.24 GAM22675.1 - 2.5e-05 24.3 3.7 0.00021 21.4 0.4 3.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM22675.1 - 0.00047 20.3 0.3 0.0013 18.9 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Mcp5_PH PF12814.2 GAM22675.1 - 0.0014 18.5 0.2 0.0044 16.9 0.1 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Acyl_transf_1 PF00698.16 GAM22676.1 - 7.7e-27 94.4 0.0 1.3e-26 93.6 0.0 1.3 1 1 0 1 1 1 1 Acyl transferase domain DUF599 PF04654.7 GAM22677.1 - 6.3e-48 162.7 13.4 7.9e-48 162.4 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF900 PF05990.7 GAM22678.1 - 5.1e-23 81.6 0.1 7.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 GAM22678.1 - 0.00052 19.7 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM22678.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Miro PF08477.8 GAM22679.1 - 0.015 15.8 0.2 0.077 13.4 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Img2 PF05046.9 GAM22680.1 - 4.2e-10 39.6 0.7 7.4e-10 38.9 0.0 1.8 3 0 0 3 3 3 1 Mitochondrial large subunit ribosomal protein (Img2) 2-Hacid_dh_C PF02826.14 GAM22681.1 - 4.5e-53 179.0 0.0 7e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 GAM22681.1 - 1.4e-22 79.5 0.1 1.6e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 GAM22681.1 - 2.7e-07 30.5 0.1 5.2e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 GAM22681.1 - 0.00022 21.1 2.1 0.00056 19.7 1.2 1.7 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 GAM22681.1 - 0.031 13.6 0.0 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 GAM22681.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ELFV_dehydrog PF00208.16 GAM22681.1 - 0.082 12.4 0.2 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAM22681.1 - 0.49 9.7 2.5 0.42 9.9 0.6 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF383 PF04063.9 GAM22682.1 - 9e-34 116.6 1.4 3.7e-33 114.6 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 GAM22682.1 - 3.3e-22 77.7 0.3 1.6e-21 75.5 0.2 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 GAM22682.1 - 0.00056 18.2 0.2 0.0012 17.2 0.2 1.6 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Menin PF05053.8 GAM22682.1 - 0.28 9.2 3.2 0.38 8.8 2.2 1.2 1 0 0 1 1 1 0 Menin Pept_tRNA_hydro PF01195.14 GAM22683.1 - 9.9e-33 113.1 0.0 1.1e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ELO PF01151.13 GAM22684.1 - 7e-62 208.9 25.8 8.1e-62 208.7 17.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family WD40 PF00400.27 GAM22685.1 - 0.0069 16.2 0.3 0.4 10.6 0.2 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 GAM22685.1 - 0.02 15.0 2.4 0.069 13.2 1.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 GAM22685.1 - 0.048 13.4 6.0 0.19 11.5 4.1 2.1 1 0 0 1 1 1 0 Ring finger domain Arf PF00025.16 GAM22686.1 - 1.2e-78 262.3 0.1 1.3e-78 262.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM22686.1 - 6.2e-15 54.8 0.0 7.7e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAM22686.1 - 2.7e-13 49.3 1.7 2e-10 39.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 GAM22686.1 - 7.8e-13 48.1 0.0 8.7e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAM22686.1 - 3e-12 46.2 0.0 3.5e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM22686.1 - 2.8e-08 34.2 0.0 4.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM22686.1 - 8.4e-06 25.7 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM22686.1 - 0.0043 16.5 0.2 0.025 14.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 GAM22686.1 - 0.0082 15.2 0.4 0.018 14.1 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 GAM22686.1 - 0.06 13.2 0.1 0.13 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain PAS_8 PF13188.1 GAM22686.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain Peptidase_M8 PF01457.11 GAM22687.1 - 1.7e-49 168.5 0.3 2.6e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 Leishmanolysin ECH PF00378.15 GAM22688.1 - 1.3e-58 198.0 0.2 1.5e-58 197.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAM22688.1 - 2.7e-05 24.2 0.1 7.3e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Arb2 PF09757.4 GAM22689.1 - 4e-18 65.4 0.0 6.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Abhydrolase_6 PF12697.2 GAM22689.1 - 2e-06 27.8 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM22689.1 - 0.00042 19.9 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 GAM22689.1 - 0.00046 19.8 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 GAM22689.1 - 0.00097 18.9 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 GAM22689.1 - 0.031 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Ser_hydrolase PF06821.8 GAM22689.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Cutinase PF01083.17 GAM22689.1 - 0.052 13.2 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 GAM22689.1 - 0.095 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SLAC1 PF03595.12 GAM22690.1 - 0.082 11.5 1.4 1.2 7.6 0.2 2.0 2 0 0 2 2 2 0 Voltage-dependent anion channel Herpes_US9 PF06072.6 GAM22690.1 - 0.27 11.1 0.2 0.27 11.1 0.1 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 BSD PF03909.12 GAM22691.1 - 2e-12 46.6 0.3 6.8e-12 44.9 0.2 2.0 1 0 0 1 1 1 1 BSD domain DUF3276 PF11680.3 GAM22691.1 - 0.02 14.6 5.1 0.044 13.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) DUF501 PF04417.7 GAM22691.1 - 0.23 11.2 3.3 0.1 12.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF501) SelR PF01641.13 GAM22693.1 - 2.1e-54 182.4 0.4 2.4e-54 182.3 0.3 1.0 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 GAM22693.1 - 0.016 14.9 0.5 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 GAM22693.1 - 0.018 15.0 2.7 0.16 12.0 1.9 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 GAM22693.1 - 1.7 8.5 6.3 12 5.8 4.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.1 GAM22693.1 - 2.6 7.9 7.5 2.9 7.8 0.1 3.0 2 2 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 RasGEF PF00617.14 GAM22694.1 - 3e-60 203.1 0.4 7.7e-60 201.8 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM22694.1 - 4.5e-25 87.7 3.9 3.5e-24 84.8 0.6 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif CDP-OH_P_transf PF01066.16 GAM22695.1 - 4.8e-15 55.6 13.6 4.8e-15 55.6 9.5 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ORMDL PF04061.9 GAM22696.1 - 4.8e-40 136.2 5.0 5.4e-40 136.0 3.5 1.0 1 0 0 1 1 1 1 ORMDL family Rer1 PF03248.8 GAM22696.1 - 0.0044 16.6 1.4 0.13 11.7 0.3 2.2 2 0 0 2 2 2 1 Rer1 family DUF457 PF04307.9 GAM22696.1 - 0.094 12.0 4.6 0.12 11.6 3.2 1.2 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) DUF846 PF05832.7 GAM22696.1 - 0.84 9.3 8.4 0.16 11.6 2.8 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) ERO1 PF04137.10 GAM22697.1 - 3.1e-110 368.5 1.0 4.5e-110 368.0 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RNase_H PF00075.19 GAM22697.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 RNase H FlgN PF05130.7 GAM22697.1 - 0.23 11.7 1.4 3.3 7.9 0.2 2.1 2 0 0 2 2 2 0 FlgN protein WAC_Acf1_DNA_bd PF10537.4 GAM22698.1 - 6.7e-28 96.8 1.4 2.1e-27 95.2 1.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 GAM22698.1 - 3.8e-19 68.1 1.7 1e-18 66.8 1.2 1.7 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 GAM22698.1 - 0.00099 18.9 0.5 0.0037 17.1 0.3 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 GAM22698.1 - 0.012 15.4 0.0 0.055 13.4 0.0 2.1 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 GAM22698.1 - 0.024 14.3 0.0 0.19 11.5 0.0 2.4 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 SAP PF02037.22 GAM22699.1 - 4.6e-12 45.1 0.4 1.3e-11 43.6 0.2 1.9 2 0 0 2 2 2 1 SAP domain DTHCT PF08070.6 GAM22699.1 - 0.066 13.8 10.9 0.12 13.0 7.5 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Rho_N PF07498.7 GAM22699.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain Dicty_REP PF05086.7 GAM22699.1 - 0.17 9.5 0.9 0.2 9.4 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mating_C PF12737.2 GAM22699.1 - 0.23 10.3 9.1 0.32 9.8 6.3 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Stress-antifung PF01657.12 GAM22699.1 - 0.5 10.7 6.4 1.5 9.2 4.5 1.8 1 1 0 1 1 1 0 Salt stress response/antifungal Med3 PF11593.3 GAM22699.1 - 0.86 8.7 7.5 1.2 8.3 5.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DNA_ligase_ZBD PF03119.11 GAM22699.1 - 2.8 7.7 8.9 0.78 9.5 0.5 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain SRP-alpha_N PF04086.8 GAM22699.1 - 4.1 6.6 9.5 5.3 6.3 6.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BetaGal_dom4_5 PF13364.1 GAM22700.1 - 0.0051 17.0 0.0 0.0076 16.4 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase jelly roll domain Cna_B PF05738.8 GAM22702.1 - 3.9e-08 32.9 11.7 0.00015 21.4 0.5 4.2 5 0 0 5 5 5 3 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM22702.1 - 4.8e-08 32.9 0.4 0.36 10.9 0.0 3.7 4 0 0 4 4 4 3 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 GAM22702.1 - 0.00014 21.7 0.1 0.29 10.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2012) FlgD_ig PF13860.1 GAM22702.1 - 0.004 16.8 0.2 2.6 7.8 0.1 3.0 2 1 0 2 2 2 2 FlgD Ig-like domain Tub_2 PF04525.7 GAM22702.1 - 0.025 13.9 0.0 0.32 10.3 0.0 2.3 2 0 0 2 2 2 0 Tubby C 2 MG1 PF11974.3 GAM22702.1 - 0.029 14.8 0.0 8.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Alpha-2-macroglobulin MG1 domain Y_Y_Y PF07495.8 GAM22702.1 - 0.13 12.0 3.0 0.95 9.2 0.1 3.2 3 0 0 3 3 3 0 Y_Y_Y domain DUF3426 PF11906.3 GAM22702.1 - 0.18 11.4 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) LTD PF00932.14 GAM22702.1 - 1 9.4 4.7 5.5 7.0 0.7 3.3 3 1 0 3 3 3 0 Lamin Tail Domain Big_3_4 PF13754.1 GAM22702.1 - 3.2 8.1 7.7 27 5.1 0.8 3.4 3 1 1 4 4 4 0 Bacterial Ig-like domain (group 3) Ank_2 PF12796.2 GAM22703.1 - 0.0035 17.6 1.5 0.094 13.0 0.2 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) WD40 PF00400.27 GAM22704.1 - 9.6e-59 193.3 19.9 7.5e-10 38.3 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 GAM22704.1 - 8.2e-16 57.4 2.7 1.6e-15 56.5 1.9 1.5 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.1 GAM22704.1 - 8.8e-09 35.1 0.1 0.089 12.5 0.0 4.6 2 2 2 4 4 4 3 Ciliary BBSome complex subunit 2, middle region F-box PF00646.28 GAM22704.1 - 1.8e-05 24.2 4.3 5.2e-05 22.7 3.0 1.8 1 0 0 1 1 1 1 F-box domain DUF3312 PF11768.3 GAM22704.1 - 0.0078 14.4 0.7 0.35 9.0 0.0 2.7 2 1 2 4 4 4 1 Protein of unknown function (DUF3312) zf-CW PF07496.10 GAM22704.1 - 1.6 8.5 4.9 1 9.1 1.7 2.0 2 0 0 2 2 2 0 CW-type Zinc Finger UbiA PF01040.13 GAM22705.1 - 6.3e-23 81.2 20.3 8.6e-23 80.8 14.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MBOAT PF03062.14 GAM22706.1 - 1.5e-22 80.1 35.8 1.8e-22 79.9 24.5 1.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAM22706.1 - 0.00056 19.9 7.0 0.00073 19.5 3.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Ras PF00071.17 GAM22707.1 - 2.6e-43 147.1 0.6 3.1e-43 146.9 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM22707.1 - 8e-16 58.6 0.1 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM22707.1 - 4.2e-14 52.1 0.2 5e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM22707.1 - 1.4e-11 43.9 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM22707.1 - 2.4e-05 24.2 0.1 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM22707.1 - 0.00013 21.4 0.3 0.00027 20.4 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM22707.1 - 0.00054 19.2 0.0 0.0016 17.7 0.0 1.6 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAM22707.1 - 0.0014 17.9 0.3 0.002 17.4 0.2 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B CPT PF07931.7 GAM22707.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ArgK PF03308.11 GAM22707.1 - 0.032 13.0 0.2 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 ArgK protein ICL PF00463.16 GAM22708.1 - 5.9e-147 490.0 3.1 1.8e-80 270.6 0.1 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.1 GAM22708.1 - 7.1e-17 61.4 0.0 1.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pkinase PF00069.20 GAM22709.1 - 2.1e-61 207.3 0.1 4.3e-61 206.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22709.1 - 9.6e-23 80.5 0.0 1.9e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22709.1 - 4.9e-09 35.5 0.0 5.8e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM22709.1 - 0.073 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pneumo_phosprot PF02478.11 GAM22709.1 - 1.3 8.4 9.8 2.2 7.7 6.8 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein RP-C_C PF11800.3 GAM22709.1 - 2.5 7.7 6.3 5.9 6.5 4.3 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Porin_3 PF01459.17 GAM22710.1 - 1.9e-20 73.3 2.1 1.4e-16 60.5 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic porin DUF2490 PF10677.4 GAM22710.1 - 0.042 13.1 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) OMP_b-brl PF13505.1 GAM22710.1 - 0.15 12.0 2.6 0.29 11.0 0.1 2.3 1 1 0 2 2 2 0 Outer membrane protein beta-barrel domain RasGAP PF00616.14 GAM22712.1 - 8.4e-48 162.6 0.0 1.4e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 GAM22712.1 - 3.1e-18 65.4 0.0 6.7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain SR-25 PF10500.4 GAM22712.1 - 0.14 11.6 3.0 0.42 10.0 2.1 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SSP160 PF06933.6 GAM22712.1 - 1.3 6.9 6.1 1.9 6.3 4.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RtcB PF01139.12 GAM22713.1 - 2.1e-143 478.3 0.0 2.6e-143 478.0 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB AAA PF00004.24 GAM22715.1 - 8.4e-41 139.2 0.3 1.5e-38 131.9 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM22715.1 - 7.9e-06 25.0 0.5 7.4e-05 21.9 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAM22715.1 - 6.7e-05 23.7 0.2 0.00034 21.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 GAM22715.1 - 9.7e-05 22.5 0.2 0.0039 17.3 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.9 GAM22715.1 - 0.00028 20.8 0.0 0.011 15.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAM22715.1 - 0.00033 20.5 0.0 0.0016 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 GAM22715.1 - 0.00041 20.1 0.3 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 GAM22715.1 - 0.00069 19.3 0.1 0.011 15.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM22715.1 - 0.00079 19.4 1.7 0.022 14.7 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM22715.1 - 0.00085 18.7 0.0 0.003 16.9 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 GAM22715.1 - 0.0011 18.6 5.3 0.094 12.4 0.1 4.5 5 0 0 5 5 4 1 Part of AAA domain AAA_14 PF13173.1 GAM22715.1 - 0.0013 18.6 0.0 0.0088 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM22715.1 - 0.002 17.2 0.7 0.0095 15.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 GAM22715.1 - 0.0026 16.5 0.5 0.008 14.9 0.1 1.9 1 1 1 2 2 2 1 TIP49 C-terminus Guanylate_kin PF00625.16 GAM22715.1 - 0.0064 15.9 0.6 3.1 7.2 0.0 4.1 4 0 0 4 4 4 1 Guanylate kinase Bac_DnaA PF00308.13 GAM22715.1 - 0.0081 15.8 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_18 PF13238.1 GAM22715.1 - 0.0095 16.2 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM22715.1 - 0.0095 15.0 0.1 0.027 13.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 GAM22715.1 - 0.033 13.5 0.4 0.19 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM22715.1 - 0.039 13.9 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain Ded_cyto PF06920.8 GAM22716.1 - 5.3e-40 136.6 1.4 5.3e-40 136.6 1.0 2.5 4 0 0 4 4 4 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM22716.1 - 3.9e-35 121.1 3.2 2e-33 115.6 0.7 3.7 4 0 0 4 4 4 1 C2 domain in Dock180 and Zizimin proteins WD40 PF00400.27 GAM22717.1 - 5e-14 51.5 1.1 1.1 9.2 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat His_Phos_1 PF00300.17 GAM22718.1 - 4.9e-32 111.1 0.0 8.9e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pro_isomerase PF00160.16 GAM22718.1 - 4e-13 49.8 0.0 3.1e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Apis_Csd PF11671.3 GAM22719.1 - 0.033 13.9 2.1 0.053 13.3 1.5 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein zf-C2H2_4 PF13894.1 GAM22719.1 - 0.048 14.0 3.3 0.15 12.4 2.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger FF PF01846.14 GAM22720.1 - 1.7e-41 139.9 22.3 3.4e-09 36.5 0.4 6.9 6 0 0 6 6 6 6 FF domain WW PF00397.21 GAM22720.1 - 1e-19 70.0 10.8 8.5e-11 41.5 2.0 2.9 2 0 0 2 2 2 2 WW domain Pet127 PF08634.5 GAM22721.1 - 1.1e-84 283.8 3.7 1.6e-84 283.3 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 COX4 PF02936.9 GAM22722.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV MacB_PCD PF12704.2 GAM22722.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain ATP-synt_F PF01990.12 GAM22723.1 - 1.3e-30 105.5 0.6 1.7e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 GAM22723.1 - 0.02 13.8 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase LPAM_2 PF13627.1 GAM22723.1 - 0.033 13.8 0.6 0.057 13.1 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DSPc PF00782.15 GAM22724.1 - 1.5e-30 105.4 0.0 2.6e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM22724.1 - 1.9e-05 24.1 0.1 6.9e-05 22.2 0.0 1.8 1 1 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 GAM22724.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) EIF_2_alpha PF07541.7 GAM22725.1 - 1.7e-33 114.7 0.0 3.8e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 GAM22725.1 - 2.3e-11 43.6 1.5 4.7e-11 42.6 1.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DUF4535 PF15054.1 GAM22725.1 - 0.039 13.3 0.1 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) EXS PF03124.9 GAM22726.1 - 1.7e-75 254.1 38.9 2.8e-75 253.5 26.9 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAM22726.1 - 4.7e-30 105.2 0.9 1.5e-18 67.6 0.0 2.1 1 1 1 2 2 2 2 SPX domain DEAD PF00270.24 GAM22727.1 - 7.3e-19 67.8 0.0 2.8e-18 65.9 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM22727.1 - 1.6e-13 50.8 4.4 5.5e-13 49.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM22727.1 - 5.8e-06 26.0 0.0 2.7e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2003 PF09404.5 GAM22728.1 - 1.1e-32 113.0 1.4 4.1e-26 91.4 0.1 2.4 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF2003) SBF2 PF12335.3 GAM22729.1 - 2.1e-10 40.3 0.2 2.1e-10 40.3 0.1 2.6 3 0 0 3 3 3 1 Myotubularin protein CH PF00307.26 GAM22729.1 - 3.4e-10 39.9 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 1 1 Calponin homology (CH) domain DZR PF12773.2 GAM22729.1 - 0.00023 20.9 8.9 0.0051 16.5 0.9 2.4 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAM22729.1 - 0.00024 20.4 9.2 0.01 15.2 3.0 2.6 2 0 0 2 2 2 2 zinc-ribbon domain Atg14 PF10186.4 GAM22729.1 - 0.0005 19.1 22.7 0.00065 18.7 1.9 3.0 3 0 0 3 3 3 2 UV radiation resistance protein and autophagy-related subunit 14 zf-ribbon_3 PF13248.1 GAM22729.1 - 0.00099 18.2 5.6 0.038 13.2 1.5 2.5 2 0 0 2 2 2 1 zinc-ribbon domain Lipoprotein_7 PF01540.11 GAM22729.1 - 0.0017 17.4 0.1 0.0017 17.4 0.1 2.4 2 0 0 2 2 2 1 Adhesin lipoprotein CDC24 PF06395.6 GAM22729.1 - 0.0062 16.5 0.1 0.049 13.6 0.0 2.5 2 0 0 2 2 2 1 CDC24 Calponin ATG16 PF08614.6 GAM22729.1 - 0.0078 16.0 4.6 0.0078 16.0 3.2 3.0 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) IncA PF04156.9 GAM22729.1 - 0.01 15.4 30.0 0.051 13.1 3.3 3.0 3 0 0 3 3 3 0 IncA protein CAMSAP_CH PF11971.3 GAM22729.1 - 0.014 15.0 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain GRAB PF10375.4 GAM22729.1 - 0.045 13.4 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 GRIP-related Arf-binding domain APG6 PF04111.7 GAM22729.1 - 0.17 10.8 21.0 0.11 11.4 3.2 2.7 3 0 0 3 3 3 0 Autophagy protein Apg6 Striatin PF08232.7 GAM22729.1 - 0.34 11.2 31.5 0.076 13.3 7.7 3.7 3 1 0 3 3 3 0 Striatin family DUF812 PF05667.6 GAM22729.1 - 0.42 9.0 20.4 0.17 10.3 4.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF812) TACC PF05010.9 GAM22729.1 - 0.52 10.0 20.6 0.32 10.7 0.9 2.9 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC) ADIP PF11559.3 GAM22729.1 - 1.1 9.1 40.1 4.7 7.1 7.6 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding FliD_C PF07195.7 GAM22729.1 - 2.4 7.3 22.1 0.19 10.9 3.6 2.7 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus GAS PF13851.1 GAM22729.1 - 3.8 6.6 37.0 2.3 7.3 8.9 3.4 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding PRTP PF01366.13 GAM22729.1 - 5 4.9 15.6 1.7 6.5 1.1 2.3 2 0 0 2 2 2 0 Herpesvirus processing and transport protein AAA_23 PF13476.1 GAM22729.1 - 6.2 7.0 21.1 0.31 11.3 2.7 2.9 3 0 0 3 3 3 0 AAA domain SlyX PF04102.7 GAM22729.1 - 7.3 7.0 31.7 6.3 7.2 6.4 4.4 4 1 0 4 4 3 0 SlyX Kelch_6 PF13964.1 GAM22730.1 - 3.7e-15 55.3 11.8 2.8e-05 24.1 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM22730.1 - 1.7e-12 46.8 8.9 0.002 17.8 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM22730.1 - 1.9e-12 46.9 2.1 0.00012 22.1 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22730.1 - 1.1e-08 34.4 17.6 0.0002 20.8 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 GAM22730.1 - 4e-05 23.2 8.2 0.022 14.5 0.4 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM22730.1 - 0.00071 19.4 13.5 0.018 14.9 0.6 4.4 5 0 0 5 5 5 2 Kelch motif Sec23_trunk PF04811.10 GAM22731.1 - 2.4e-43 148.2 0.0 4e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM22731.1 - 6.2e-20 70.5 0.1 1.7e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAM22731.1 - 5.4e-16 58.8 0.0 1.5e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM22731.1 - 2.7e-15 55.6 3.1 5.3e-15 54.6 2.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAM22731.1 - 2.2e-05 24.0 0.0 9.3e-05 22.0 0.0 2.1 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L4 PF00573.17 GAM22732.1 - 3.7e-40 137.3 0.2 6.3e-40 136.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 GAM22732.1 - 9.4e-25 86.3 4.2 1e-23 82.9 2.7 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ras PF00071.17 GAM22735.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Ras family RHS_repeat PF05593.9 GAM22736.1 - 2.3e-16 59.5 63.6 0.0026 17.8 1.2 15.5 11 3 3 16 16 16 9 RHS Repeat Aldedh PF00171.17 GAM22737.1 - 1.5e-126 422.4 0.2 1.8e-126 422.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Senescence PF06911.7 GAM22738.1 - 2.4e-23 82.7 7.1 6.2e-23 81.4 4.9 1.7 1 0 0 1 1 1 1 Senescence-associated protein PH PF00169.24 GAM22738.1 - 1.7e-08 34.6 0.1 9.6e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM22738.1 - 0.013 15.7 0.0 0.045 13.9 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain CPSF_A PF03178.10 GAM22738.1 - 0.035 13.2 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region PDEase_I PF00233.14 GAM22739.1 - 1.4e-73 247.5 5.4 1.4e-73 247.5 3.8 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 GAM22739.1 - 3.4e-26 91.4 0.4 7.4e-26 90.3 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain FNIP PF05725.7 GAM22740.1 - 1.6e-56 188.0 36.1 1.5e-13 50.4 0.1 9.7 6 2 4 10 10 10 9 FNIP Repeat Pam16 PF03656.8 GAM22741.1 - 2.2e-16 59.7 0.0 2.7e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Pam16 3HCDH PF00725.17 GAM22741.1 - 0.12 12.8 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DNA_binding_1 PF01035.15 GAM22742.1 - 1.6e-25 88.6 0.0 2.4e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.10 GAM22742.1 - 0.0094 16.5 0.0 0.085 13.4 0.0 2.2 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Proteasom_Rpn13 PF04683.8 GAM22743.1 - 5.7e-21 74.3 0.3 6.7e-21 74.1 0.2 1.1 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor FNIP PF05725.7 GAM22744.1 - 5.9e-40 134.9 9.2 1.3e-11 44.2 0.1 5.4 2 1 3 6 6 6 6 FNIP Repeat DUF1769 PF08588.5 GAM22744.1 - 0.00034 20.5 4.6 1.2 9.1 0.0 4.9 2 2 4 6 6 6 3 Protein of unknown function (DUF1769) RCC1 PF00415.13 GAM22745.1 - 8e-87 285.3 19.0 3e-14 52.9 0.0 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM22745.1 - 1.9e-43 145.2 30.9 1.4e-07 30.9 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAM22745.1 - 1.1e-22 80.1 5.7 9.9e-15 54.4 0.3 3.1 3 0 0 3 3 3 2 BTB/POZ domain CBM_X PF06204.6 GAM22745.1 - 2.5 7.6 5.8 9.6 5.7 0.0 3.8 4 0 0 4 4 4 0 Putative carbohydrate binding domain CH PF00307.26 GAM22746.1 - 4.4e-11 42.7 0.1 9.6e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 GAM22746.1 - 0.079 13.0 0.3 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 CDC24 Calponin YbjN PF10722.4 GAM22747.1 - 0.09 12.8 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator ABC_transp_aux PF09822.4 GAM22747.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system vATP-synt_AC39 PF01992.11 GAM22748.1 - 2.8e-96 322.6 0.1 3.1e-96 322.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pkr1 PF08636.5 GAM22749.1 - 0.14 12.2 2.9 0.22 11.6 2.0 1.3 1 0 0 1 1 1 0 ER protein Pkr1 DUF2259 PF10016.4 GAM22749.1 - 0.52 9.9 6.3 1.3 8.6 4.3 1.7 1 1 0 1 1 1 0 Predicted secreted protein (DUF2259) Hid1 PF12722.2 GAM22749.1 - 1.4 6.5 13.4 1.9 6.0 9.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 GAM22749.1 - 3.9 5.0 10.5 5.3 4.6 7.3 1.2 1 0 0 1 1 1 0 Ycf1 Cna_B PF05738.8 GAM22750.1 - 5.8e-26 90.0 48.9 0.0033 17.1 0.1 14.5 12 0 0 12 12 12 11 Cna protein B-type domain DUF3244 PF11589.3 GAM22750.1 - 7.2e-22 77.1 0.1 0.011 15.4 0.0 12.1 12 0 0 12 12 12 4 Domain of unknown function (DUF3244) DUF2012 PF09430.5 GAM22750.1 - 2.4e-12 46.7 0.0 13 5.6 0.0 11.0 12 0 0 12 12 12 3 Protein of unknown function (DUF2012) Inh PF02974.9 GAM22750.1 - 1.3e-05 24.7 3.2 38 3.9 0.0 8.0 9 0 0 9 9 9 0 Protease inhibitor Inh TAFII28 PF04719.9 GAM22750.1 - 0.011 15.4 0.0 1.7e+02 2.0 0.0 6.1 7 0 0 7 7 7 0 hTAFII28-like protein conserved region HDV_ag PF01517.13 GAM22750.1 - 6.2 6.4 7.9 2.1e+02 1.4 0.0 6.1 8 0 0 8 8 8 0 Hepatitis delta virus delta antigen Cna_B PF05738.8 GAM22751.1 - 1.3e-14 53.7 37.8 0.02 14.6 0.2 9.0 7 2 1 8 8 8 7 Cna protein B-type domain DUF3244 PF11589.3 GAM22751.1 - 5.9e-10 38.8 1.9 0.38 10.4 0.0 6.7 7 0 0 7 7 7 2 Domain of unknown function (DUF3244) DUF2012 PF09430.5 GAM22751.1 - 1.8e-07 31.0 0.0 4.3 7.1 0.0 6.1 7 0 0 7 7 7 2 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 GAM22751.1 - 2.6e-07 30.5 13.7 4.2 7.4 0.0 8.9 7 2 1 8 8 8 2 Carboxypeptidase regulatory-like domain DUF3659 PF12396.3 GAM22751.1 - 0.025 14.2 3.2 14 5.4 0.1 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF3659) Inh PF02974.9 GAM22751.1 - 0.056 13.0 5.6 9 5.9 0.0 5.4 7 0 0 7 7 7 0 Protease inhibitor Inh Y_Y_Y PF07495.8 GAM22751.1 - 0.5 10.1 14.7 1.7 8.4 0.0 6.7 9 0 0 9 9 9 0 Y_Y_Y domain hDGE_amylase PF14701.1 GAM22751.1 - 5 5.9 4.4 1.4e+02 1.1 0.0 4.1 6 0 0 6 6 6 0 glucanotransferase domain of human glycogen debranching enzyme Bradykinin PF06753.7 GAM22751.1 - 9 5.9 5.8 43 3.7 0.4 2.8 2 0 0 2 2 2 0 Bradykinin Peptidase_M24 PF00557.19 GAM22752.1 - 2e-54 184.3 0.0 2.7e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAM22752.1 - 6.7e-32 109.6 0.0 1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HTH_37 PF13744.1 GAM22752.1 - 0.088 12.6 0.3 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain PNTB PF02233.11 GAM22753.1 - 6.1e-185 615.4 21.9 6.1e-185 615.4 15.2 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 GAM22753.1 - 5e-57 192.1 0.9 1.3e-56 190.7 0.6 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 GAM22753.1 - 1.2e-45 154.8 0.1 2.4e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 GAM22753.1 - 1.5e-30 105.2 5.8 1.5e-30 105.2 4.0 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 GAM22753.1 - 0.00036 19.7 2.8 0.11 11.6 0.1 3.6 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 GAM22753.1 - 0.0036 16.8 0.3 0.011 15.2 0.2 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 GAM22753.1 - 0.089 12.6 0.4 0.25 11.2 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S6e PF01092.14 GAM22754.1 - 3.5e-53 178.6 0.1 6.5e-53 177.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e AAR2 PF05282.6 GAM22755.1 - 3.8e-76 256.3 0.3 5.3e-76 255.9 0.2 1.1 1 0 0 1 1 1 1 AAR2 protein APC_CDC26 PF10471.4 GAM22755.1 - 2.2 9.0 11.0 0.67 10.7 1.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2043 PF09740.4 GAM22756.1 - 3.4e-23 81.8 0.0 1e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2043) SSP160 PF06933.6 GAM22756.1 - 0.21 9.5 1.3 0.29 9.0 0.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ank_2 PF12796.2 GAM22757.1 - 1.3e-10 41.4 0.5 1.1e-05 25.6 0.0 2.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM22757.1 - 5.3e-06 26.1 0.5 0.11 12.7 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 GAM22757.1 - 0.00085 19.0 2.7 0.23 11.3 0.3 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 GAM22757.1 - 0.0072 16.8 0.0 0.24 11.9 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Cna_B PF05738.8 GAM22757.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Cna protein B-type domain PPP4R2 PF09184.6 GAM22760.1 - 5.6 6.4 8.2 9.9 5.6 5.7 1.4 1 0 0 1 1 1 0 PPP4R2 7tm_2 PF00002.19 GAM22761.1 - 7.4e-08 31.7 19.9 7.7e-08 31.7 13.3 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3_C PF11970.3 GAM22761.1 - 0.00034 20.3 2.0 0.00034 20.3 1.4 2.1 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 GAM22761.1 - 0.0024 17.0 20.5 0.0024 17.0 14.2 1.7 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) PH PF00169.24 GAM22762.1 - 4.2e-16 59.0 0.1 5.8e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM22762.1 - 3.4e-05 24.0 1.6 0.0003 21.0 1.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM22762.1 - 3.6e-05 23.7 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM22762.1 - 0.0015 18.6 0.2 0.011 15.8 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 GAM22762.1 - 0.029 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3608 PF12257.3 GAM22764.1 - 2.9e-67 226.5 0.1 4.6e-67 225.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 GAM22764.1 - 2e-17 62.6 0.3 6.8e-17 60.9 0.2 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGEF PF00621.15 GAM22765.1 - 1.4e-41 142.3 1.8 3e-41 141.2 0.1 2.2 2 0 0 2 2 2 1 RhoGEF domain Synaptobrevin PF00957.16 GAM22766.1 - 9.3e-31 105.2 3.4 1.3e-30 104.7 2.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAM22766.1 - 9.5e-25 85.9 0.0 1.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Corona_S2 PF01601.11 GAM22766.1 - 0.014 13.5 0.1 0.014 13.4 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein SRP-alpha_N PF04086.8 GAM22766.1 - 0.034 13.5 0.3 0.044 13.1 0.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MSC PF09402.5 GAM22766.1 - 0.036 12.7 0.1 0.049 12.3 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RhoGEF PF00621.15 GAM22767.1 - 2e-16 60.4 0.1 2.3e-16 60.2 0.1 1.0 1 0 0 1 1 1 1 RhoGEF domain Gag_p30 PF02093.11 GAM22767.1 - 0.047 12.9 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 Gag P30 core shell protein EcoEI_R_C PF08463.5 GAM22767.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal DUF2636 PF11120.3 GAM22768.1 - 0.18 11.3 6.0 0.072 12.6 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Lactamase_B_2 PF12706.2 GAM22769.1 - 1.8e-44 151.6 0.0 1.9e-37 128.6 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM22769.1 - 4.6e-05 23.1 0.8 0.00022 20.9 0.4 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 GAM22769.1 - 9.7e-05 21.7 0.0 0.00022 20.6 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_3 PF13483.1 GAM22769.1 - 0.0023 17.6 0.0 0.016 14.9 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain FH2 PF02181.18 GAM22770.1 - 1.1e-83 281.2 0.4 1.1e-83 281.2 0.3 2.9 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 GAM22770.1 - 0.0013 18.1 1.8 0.0013 18.1 1.2 2.7 3 1 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAM22770.1 - 0.13 11.5 0.0 0.13 11.5 0.0 3.1 3 0 0 3 3 3 0 Diaphanous GTPase-binding Domain Cna_B PF05738.8 GAM22771.1 - 0.021 14.5 0.2 0.063 13.0 0.1 1.8 1 0 0 1 1 1 0 Cna protein B-type domain AAA_16 PF13191.1 GAM22771.1 - 0.043 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CarboxypepD_reg PF13620.1 GAM22771.1 - 0.055 13.5 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain AAA_5 PF07728.9 GAM22771.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAM22771.1 - 0.063 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Kelch_6 PF13964.1 GAM22772.1 - 5.9e-11 42.0 4.5 9.6e-07 28.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM22772.1 - 1.7e-09 37.2 4.3 5.7e-05 22.8 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM22772.1 - 5.8e-09 35.3 5.4 9.1e-06 25.1 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM22772.1 - 1.3e-06 28.3 2.8 0.0055 16.8 0.0 3.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM22772.1 - 1.3e-05 24.7 1.6 0.036 13.8 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM22772.1 - 0.00032 20.5 9.2 0.11 12.5 1.2 3.2 3 0 0 3 3 3 2 Kelch motif Disulph_isomer PF06491.6 GAM22772.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase BRE1 PF08647.6 GAM22772.1 - 0.097 12.6 0.2 0.61 10.1 0.0 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase THOC7 PF05615.8 GAM22773.1 - 1.3e-18 67.6 5.9 1.3e-18 67.6 4.1 2.1 1 1 0 2 2 2 1 Tho complex subunit 7 Glu-tRNAGln PF02686.10 GAM22773.1 - 0.14 12.0 3.0 2.6 7.9 0.1 2.8 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit DUF948 PF06103.6 GAM22773.1 - 0.21 11.4 1.9 0.41 10.5 0.5 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.14 GAM22773.1 - 0.33 8.7 7.1 0.41 8.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 GAM22773.1 - 0.99 9.2 10.9 0.97 9.2 6.7 1.5 1 1 0 1 1 1 0 Tropomyosin like Tup_N PF08581.5 GAM22773.1 - 1.4 9.1 12.0 1.1 9.5 1.5 2.5 2 0 0 2 2 2 0 Tup N-terminal DUF3430 PF11912.3 GAM22774.1 - 6.4e-20 71.8 12.0 8e-20 71.5 8.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Fer4 PF00037.22 GAM22775.1 - 1.5e-14 52.8 17.4 8.6e-09 34.6 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 GAM22775.1 - 2.5e-12 46.9 11.2 4e-12 46.3 7.8 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 GAM22775.1 - 1e-10 41.2 24.1 2.1e-08 33.7 9.5 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 GAM22775.1 - 1.7e-10 41.4 6.2 6.9e-05 23.5 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 GAM22775.1 - 6.8e-10 39.0 11.7 1.4e-09 38.0 8.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 GAM22775.1 - 1.1e-09 38.0 5.3 5.5e-05 22.9 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 GAM22775.1 - 1.1e-08 35.0 20.3 8.3e-06 25.7 8.5 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 GAM22775.1 - 2.1e-08 33.5 14.7 0.00011 21.9 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 GAM22775.1 - 1.4e-07 31.0 18.3 0.0011 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 GAM22775.1 - 2.8e-07 30.3 12.6 0.00067 19.7 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 GAM22775.1 - 6.9e-06 26.3 10.2 0.00053 20.2 8.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 GAM22775.1 - 2.6e-05 24.5 10.6 0.013 15.8 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 GAM22775.1 - 0.0013 19.0 15.0 0.12 12.7 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 GAM22775.1 - 0.0031 18.0 13.0 0.33 11.5 1.3 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 GAM22775.1 - 0.0081 16.6 18.7 0.017 15.6 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 GAM22775.1 - 0.24 11.5 6.4 1.3 9.2 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain LRR_4 PF12799.2 GAM22776.1 - 6e-06 25.7 10.8 0.00046 19.7 2.0 7.7 6 3 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM22776.1 - 7.7e-05 22.2 25.0 3.9 7.8 0.6 8.8 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 GAM22776.1 - 0.0017 18.2 36.5 0.17 12.0 0.1 9.3 12 0 0 12 12 12 4 Leucine Rich repeat LRR_8 PF13855.1 GAM22776.1 - 0.0021 17.7 4.1 0.0021 17.7 2.9 6.6 3 2 2 6 6 6 2 Leucine rich repeat TPR_11 PF13414.1 GAM22777.1 - 8.2e-07 28.5 3.1 2.1e-06 27.3 1.3 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 GAM22777.1 - 1.1e-05 25.0 5.2 0.0091 15.8 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM22777.1 - 1.3e-05 25.4 0.5 0.077 13.6 0.0 4.0 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM22777.1 - 0.00032 20.1 2.8 0.27 10.9 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM22777.1 - 0.003 17.8 1.8 0.36 11.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM22777.1 - 0.0031 18.1 0.7 1.1 9.9 0.0 3.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM22777.1 - 0.019 15.0 3.9 0.91 9.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM22777.1 - 0.16 11.8 5.5 2.8 7.9 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM22777.1 - 0.17 11.7 1.6 8.5 6.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM22777.1 - 0.18 11.9 2.4 1.1 9.3 0.7 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM22777.1 - 0.75 10.3 5.6 16 6.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM22777.1 - 3.5 7.6 6.1 16 5.5 0.3 3.4 2 1 3 5 5 5 0 Tetratricopeptide repeat RasGEF PF00617.14 GAM22778.1 - 1.6e-62 210.6 3.1 4.1e-62 209.2 2.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM22778.1 - 3.6e-24 84.8 0.2 1.8e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif TIG PF01833.19 GAM22779.1 - 2.6e-20 72.2 25.4 4.9e-10 39.2 0.2 4.5 3 1 1 4 4 4 4 IPT/TIG domain GATA PF00320.22 GAM22780.1 - 1.6e-13 49.7 5.9 2.8e-13 48.9 4.1 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF3923 PF13061.1 GAM22782.1 - 0.36 10.6 12.5 0.53 10.1 7.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3923) DOT1 PF08123.8 GAM22783.1 - 1.4e-29 102.9 0.0 2.3e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 GAM22783.1 - 6.6e-07 29.8 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM22783.1 - 8.6e-06 25.7 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM22783.1 - 0.0015 18.1 0.1 0.0036 16.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM22783.1 - 0.014 15.7 0.0 0.045 14.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM22783.1 - 0.022 15.2 0.2 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM22783.1 - 0.76 10.2 2.8 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain RhoGEF PF00621.15 GAM22785.1 - 1.8e-37 128.9 3.6 1.8e-37 128.9 2.5 2.6 2 1 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 GAM22785.1 - 2.6e-21 75.2 6.7 5.5e-21 74.2 4.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAM22785.1 - 2.4e-11 43.7 0.2 6.9e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM22785.1 - 0.0052 17.0 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain FYVE_2 PF02318.11 GAM22785.1 - 0.01 15.7 5.8 0.01 15.7 4.0 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger VWA_2 PF13519.1 GAM22786.1 - 1.5e-18 67.4 0.0 3.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.18 GAM22786.1 - 7.1e-07 28.5 0.1 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ras PF00071.17 GAM22786.1 - 0.0054 16.1 0.7 0.46 9.8 0.0 3.0 2 1 1 3 3 3 1 Ras family Miro PF08477.8 GAM22786.1 - 0.0074 16.7 0.5 2 8.9 0.0 3.1 1 1 1 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 GAM22786.1 - 0.036 13.5 0.1 0.093 12.2 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation OKR_DC_1_N PF03709.10 GAM22786.1 - 0.069 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Spore_GerAC PF05504.6 GAM22786.1 - 0.19 11.4 2.2 9.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Spore germination B3/ GerAC like, C-terminal RRM_5 PF13893.1 GAM22787.1 - 2e-35 120.4 0.2 7e-12 45.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22787.1 - 3e-26 91.1 0.1 8.6e-11 41.6 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM22787.1 - 1.6e-23 82.1 0.0 2.3e-06 27.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM22787.1 - 8e-05 22.3 0.0 0.0074 16.0 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 WD40 PF00400.27 GAM22788.1 - 1.2e-41 139.0 7.9 2e-08 33.7 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat NOA36 PF06524.7 GAM22788.1 - 0.0038 16.5 3.5 0.0038 16.5 2.4 3.2 2 1 1 3 3 3 1 NOA36 protein Nucleoporin_N PF08801.6 GAM22788.1 - 0.048 12.4 0.4 0.57 8.8 0.1 2.6 2 2 1 3 3 3 0 Nup133 N terminal like SDA1 PF05285.7 GAM22788.1 - 7.7 5.6 56.1 1.9 7.6 24.7 2.2 2 0 0 2 2 2 0 SDA1 Archease PF01951.11 GAM22789.1 - 5.7e-41 139.6 3.0 6.6e-41 139.4 2.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) CATSPERG PF15064.1 GAM22789.1 - 0.077 10.7 0.4 0.076 10.7 0.3 1.3 1 1 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma Pkinase PF00069.20 GAM22790.1 - 2.2e-72 243.3 0.0 4.2e-72 242.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22790.1 - 8.2e-34 116.8 0.0 1.6e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22790.1 - 2.6e-06 26.6 0.0 3.2e-05 23.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Peptidase_C1 PF00112.18 GAM22791.1 - 7.2e-50 169.8 2.5 9.1e-50 169.5 1.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 GAM22791.1 - 0.087 11.3 0.6 0.19 10.2 0.3 1.6 1 1 1 2 2 2 0 Peptidase C1-like family WW PF00397.21 GAM22792.1 - 5.6e-11 42.0 6.9 3.7e-05 23.4 0.4 2.5 2 0 0 2 2 2 2 WW domain RPEL PF02755.10 GAM22792.1 - 3.5e-05 22.9 1.4 9.8e-05 21.5 0.9 1.8 1 0 0 1 1 1 1 RPEL repeat BAF1_ABF1 PF04684.8 GAM22792.1 - 0.01 14.7 1.1 0.018 13.8 0.8 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor START PF01852.14 GAM22793.1 - 2.8e-06 26.8 0.0 6.7e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 START domain QRPTase_C PF01729.14 GAM22794.1 - 1.3e-54 184.2 0.1 1.6e-54 183.9 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 GAM22794.1 - 4.3e-22 77.7 0.0 7.5e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF3449 PF11931.3 GAM22796.1 - 4.3e-59 199.3 6.1 4.3e-59 199.3 4.2 3.7 3 2 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 GAM22796.1 - 4e-10 39.5 7.0 2.9e-08 33.6 1.8 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM22796.1 - 1.2e-07 31.6 2.0 1.2e-07 31.6 1.4 2.9 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3a60_bindingd PF12108.3 GAM22796.1 - 6.3e-07 28.8 0.4 1.6e-06 27.4 0.3 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.2 GAM22796.1 - 0.0043 17.1 7.9 0.05 13.7 0.3 3.4 3 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) Desulfoferrod_N PF06397.7 GAM22796.1 - 0.14 11.5 0.6 0.29 10.5 0.4 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain Neisseria_TspB PF05616.8 GAM22796.1 - 0.26 9.6 6.5 0.022 13.1 1.3 1.5 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein zf-C2H2_6 PF13912.1 GAM22796.1 - 0.74 9.8 6.2 0.2 11.6 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GET2 PF08690.5 GAM22796.1 - 7.3 5.7 10.0 2.3 7.4 4.2 2.0 2 1 0 2 2 2 0 GET complex subunit GET2 DUF2076 PF09849.4 GAM22797.1 - 2e-06 28.0 1.7 2.1e-06 28.0 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2613 PF11021.3 GAM22797.1 - 0.0012 18.4 1.4 0.0026 17.4 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2613) CHCH PF06747.8 GAM22797.1 - 0.0038 17.1 2.7 0.005 16.7 1.9 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 GAM22797.1 - 0.0046 16.9 0.5 0.0071 16.3 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Rick_17kDa_Anti PF05433.10 GAM22797.1 - 0.03 14.0 2.9 0.047 13.3 2.0 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1180 PF06679.7 GAM22797.1 - 1 9.2 5.9 1.4 8.8 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FNIP PF05725.7 GAM22800.1 - 6.2e-92 301.3 32.3 1.3e-10 41.0 0.1 7.6 3 1 10 13 13 13 12 FNIP Repeat FNIP PF05725.7 GAM22802.1 - 5.5e-60 199.0 11.1 8.4e-15 54.4 0.2 8.7 6 2 5 12 12 12 8 FNIP Repeat LRR_6 PF13516.1 GAM22802.1 - 0.032 14.2 1.2 3 8.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Mec-17 PF05301.6 GAM22803.1 - 0.16 11.9 2.4 0.31 10.9 0.2 2.1 1 1 1 2 2 2 0 Touch receptor neuron protein Mec-17 Glyco_hydro_16 PF00722.16 GAM22804.1 - 1.3e-20 73.4 1.3 1.3e-20 73.4 0.9 1.9 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAM22804.1 - 6.3e-07 27.9 1.0 6.3e-07 27.9 0.7 2.4 1 1 1 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) DUF605 PF04652.11 GAM22804.1 - 0.031 13.6 12.6 0.032 13.6 8.7 1.1 1 0 0 1 1 1 0 Vta1 like Rifin_STEVOR PF02009.11 GAM22804.1 - 0.54 9.8 3.6 0.81 9.2 2.5 1.3 1 0 0 1 1 1 0 Rifin/stevor family Hamartin PF04388.7 GAM22804.1 - 1.8 7.1 13.7 1.9 7.0 9.5 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.8 GAM22804.1 - 4 7.2 17.2 5.4 6.7 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_7 PF01145.20 GAM22805.1 - 1.4e-12 47.9 0.0 1.4e-12 47.9 0.0 2.4 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 GAM22805.1 - 0.014 14.9 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF2407_C PF13373.1 GAM22805.1 - 0.024 14.5 0.8 0.094 12.6 0.0 2.3 2 1 0 2 2 2 0 DUF2407 C-terminal domain 4HBT PF03061.17 GAM22806.1 - 6.4e-09 35.8 0.1 0.0047 17.0 0.0 2.6 2 0 0 2 2 2 2 Thioesterase superfamily RRM_1 PF00076.17 GAM22806.1 - 1.7e-08 33.9 0.0 5e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22806.1 - 4.5e-08 32.9 0.0 1.2e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 GAM22806.1 - 0.97 8.8 7.3 1.8 7.9 5.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 GAM22807.1 - 7.7e-80 267.7 0.1 9.1e-80 267.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22807.1 - 5.2e-36 124.0 0.1 6.2e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22807.1 - 6.6e-10 38.4 0.0 1.3e-08 34.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAM22807.1 - 0.00014 20.9 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM22807.1 - 0.00028 20.2 0.8 0.00047 19.5 0.5 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAM22807.1 - 0.00029 20.6 0.0 0.21 11.3 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM22807.1 - 0.091 12.0 0.1 0.17 11.2 0.1 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FNIP PF05725.7 GAM22808.1 - 3.4e-23 81.3 17.8 1.7e-13 50.2 0.4 7.2 7 0 0 7 7 7 3 FNIP Repeat Metallophos PF00149.23 GAM22809.1 - 3.7e-42 144.0 0.3 4.6e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RabGAP-TBC PF00566.13 GAM22810.1 - 3.6e-32 111.5 3.9 3.6e-32 111.5 2.7 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.27 GAM22812.1 - 8.1e-11 41.3 13.9 0.0022 17.7 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat HPS3_N PF14761.1 GAM22812.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 Dicty_REP PF05086.7 GAM22812.1 - 0.11 10.2 11.2 0.19 9.4 7.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF572 PF04502.8 GAM22812.1 - 0.13 11.4 1.6 0.18 10.9 1.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.8 GAM22812.1 - 1.7 8.4 5.5 2.4 7.9 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.2 GAM22813.1 - 9.9e-08 31.5 0.4 3.9e-07 29.6 0.3 2.1 1 0 0 1 1 1 1 F-box-like Cullin PF00888.17 GAM22813.1 - 4.4e-07 28.8 4.0 4.7e-07 28.7 2.2 1.4 1 1 0 1 1 1 1 Cullin family PIP5K PF01504.13 GAM22814.1 - 1.8e-73 246.7 0.5 4.3e-73 245.5 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ank PF00023.25 GAM22814.1 - 1e-31 107.1 2.0 1.4e-05 24.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 GAM22814.1 - 4.9e-31 106.9 0.3 3.3e-14 52.9 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM22814.1 - 1e-29 102.3 1.0 1.9e-12 47.3 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22814.1 - 4.7e-22 77.5 1.7 5.5e-08 32.8 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22814.1 - 3.2e-19 67.0 0.7 0.0016 18.4 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat C1_1 PF00130.17 GAM22814.1 - 6.3e-12 45.0 6.0 1.1e-11 44.3 4.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_7 PF13499.1 GAM22814.1 - 7.9e-12 45.1 8.9 1e-08 35.1 0.9 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM22814.1 - 5.6e-11 40.9 3.5 0.002 17.2 0.6 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 GAM22814.1 - 5.8e-10 38.2 4.7 0.012 15.4 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM22814.1 - 7.5e-07 28.6 5.3 0.017 14.7 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair NADPH_Ox PF08414.5 GAM22814.1 - 0.00013 21.9 1.4 0.0013 18.8 0.1 2.8 2 0 0 2 2 2 1 Respiratory burst NADPH oxidase Ketoacyl-synt_2 PF13723.1 GAM22814.1 - 0.05 12.8 0.0 0.05 12.8 0.0 2.4 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain EF-hand_5 PF13202.1 GAM22814.1 - 0.15 11.4 5.4 0.2 11.0 0.8 2.9 3 0 0 3 3 2 0 EF hand Zip PF02535.17 GAM22814.1 - 6 5.7 14.4 0.14 11.1 0.5 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter Trypan_PARP PF05887.6 GAM22814.1 - 8.6 6.1 8.5 0.37 10.6 1.1 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FAD_binding_3 PF01494.14 GAM22815.1 - 6e-23 81.4 0.0 1.6e-22 80.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 GAM22815.1 - 8.7e-05 22.4 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM22815.1 - 0.0003 19.8 0.0 0.021 13.7 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM22815.1 - 0.0031 17.5 0.2 0.012 15.6 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 GAM22815.1 - 0.0033 16.3 0.0 0.073 11.8 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.17 GAM22815.1 - 0.0089 14.9 0.2 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAM22815.1 - 0.12 12.2 0.5 1.6 8.5 0.3 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM22815.1 - 0.14 11.9 0.3 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 ThiF family HORMA PF02301.13 GAM22816.1 - 5.3e-46 156.7 0.1 6e-46 156.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain SspB PF04386.8 GAM22816.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.7 1 1 1 2 2 2 0 Stringent starvation protein B zinc_ribbon_6 PF14599.1 GAM22817.1 - 5.9e-18 64.4 0.8 5.9e-18 64.4 0.5 4.3 2 1 1 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 GAM22817.1 - 1.1e-16 60.6 24.3 1.1e-16 60.6 16.8 3.7 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 GAM22817.1 - 1.6e-10 40.6 4.8 1.6e-10 40.6 3.3 5.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM22817.1 - 5.3e-08 32.7 6.1 5.3e-08 32.7 4.2 5.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM22817.1 - 1.6e-07 30.8 5.8 1.6e-07 30.8 4.0 5.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 GAM22817.1 - 0.0001 21.7 4.0 0.0001 21.7 2.8 4.9 1 1 3 4 4 4 1 RING/Ubox like zinc-binding domain TFIIA PF03153.8 GAM22817.1 - 0.00047 20.1 2.1 0.0005 20.0 1.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 GAM22817.1 - 0.0078 15.7 3.1 0.013 14.9 2.1 1.4 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 GAM22817.1 - 0.32 10.7 1.9 0.55 10.0 1.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 GAM22817.1 - 6.6 4.6 6.0 9.7 4.0 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.22 GAM22818.1 - 3.1e-74 244.7 5.5 5.6e-24 83.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mob1_phocein PF03637.12 GAM22819.1 - 2.8e-69 232.2 0.1 3.4e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family KH_1 PF00013.24 GAM22820.1 - 7e-09 35.2 0.1 1.8e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 GAM22820.1 - 1.6e-05 24.3 1.6 2.4e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 KH domain DUF4279 PF14106.1 GAM22820.1 - 0.076 12.9 0.1 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) DUF837 PF05769.6 GAM22820.1 - 0.12 11.8 1.5 3.8 7.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF837) DUF605 PF04652.11 GAM22820.1 - 2.5 7.4 26.0 2.5 7.3 0.6 2.2 2 0 0 2 2 2 0 Vta1 like CBM49 PF09478.5 GAM22821.1 - 4.4e-17 61.9 0.1 6.4e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 VPS9 PF02204.13 GAM22822.1 - 1.1e-23 83.2 0.1 3.8e-23 81.4 0.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Pkinase PF00069.20 GAM22823.1 - 8.6e-69 231.5 0.0 1.2e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22823.1 - 3.3e-46 157.4 0.0 5.1e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM22823.1 - 2.7e-15 56.5 0.0 2.7e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 GAM22823.1 - 1.3e-05 24.3 0.0 3.2e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like SAM_1 PF00536.25 GAM22824.1 - 2.7e-07 30.6 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM22824.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4139 PF13598.1 GAM22824.1 - 8.6e-05 21.9 1.6 0.13 11.5 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) PH_11 PF15413.1 GAM22824.1 - 0.0037 17.5 0.4 0.015 15.5 0.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM22824.1 - 0.05 13.7 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain ATP-synt_ab PF00006.20 GAM22825.1 - 1e-61 208.1 0.0 1.4e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM22825.1 - 6e-18 65.3 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM22825.1 - 1.8e-10 40.8 0.4 3.4e-10 39.9 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 GAM22825.1 - 0.0006 19.6 0.2 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 HAS barrel domain Ribosomal_L18ae PF01775.12 GAM22826.1 - 1.9e-52 176.3 3.6 2.6e-52 175.9 2.5 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CD36 PF01130.16 GAM22826.1 - 0.029 12.6 0.1 0.031 12.5 0.0 1.1 1 0 0 1 1 1 0 CD36 family Acetyltransf_9 PF13527.1 GAM22827.1 - 2.1e-07 30.8 0.0 4.9e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM22827.1 - 0.0098 16.0 0.1 0.11 12.6 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Tax PF02959.11 GAM22827.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 HTLV Tax NAD_synthase PF02540.12 GAM22828.1 - 1.6e-25 89.4 0.0 6.2e-25 87.4 0.0 1.9 2 1 0 2 2 2 1 NAD synthase CN_hydrolase PF00795.17 GAM22828.1 - 2.9e-25 88.7 0.0 4.8e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GHL6 PF14871.1 GAM22829.1 - 1.7e-11 44.2 0.0 3.3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 zf-CCHC PF00098.18 GAM22829.1 - 1.5e-07 30.9 10.9 0.0011 18.7 1.1 2.6 2 0 0 2 2 2 2 Zinc knuckle Glyco_hydro_42M PF08532.5 GAM22829.1 - 7.2e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain zf-CCHC_4 PF14392.1 GAM22829.1 - 0.00046 19.8 6.4 0.081 12.6 0.5 2.6 2 0 0 2 2 2 2 Zinc knuckle DUF4015 PF13200.1 GAM22829.1 - 0.0023 16.9 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain zf-CCHC_2 PF13696.1 GAM22829.1 - 0.49 9.9 5.6 0.23 11.0 1.8 2.0 1 1 1 2 2 2 0 Zinc knuckle Ras PF00071.17 GAM22830.1 - 5.6e-59 198.1 0.0 6.6e-59 197.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM22830.1 - 5.4e-20 72.0 0.0 1e-19 71.1 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM22830.1 - 2.2e-10 40.0 0.0 2.3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM22830.1 - 1.5e-08 34.2 0.1 3.5e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM22830.1 - 0.0036 17.2 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM22830.1 - 0.021 13.9 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 GAM22830.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 GAM22830.1 - 0.14 12.2 0.1 1.1 9.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain EF-hand_7 PF13499.1 GAM22832.1 - 7.9e-13 48.3 0.1 8.6e-12 45.0 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM22832.1 - 6.4e-06 25.1 3.6 0.0026 16.9 0.1 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 GAM22832.1 - 0.0007 19.2 1.1 1 9.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain LMBR1 PF04791.11 GAM22832.1 - 0.00076 18.1 0.3 0.0013 17.4 0.2 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein EF-hand_5 PF13202.1 GAM22832.1 - 0.0032 16.7 0.4 0.39 10.1 0.0 2.8 2 0 0 2 2 2 1 EF hand Apt1 PF10351.4 GAM22832.1 - 0.0087 14.9 16.6 0.014 14.3 11.5 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain EF-hand_8 PF13833.1 GAM22832.1 - 0.013 15.0 2.8 0.98 9.0 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair SOBP PF15279.1 GAM22832.1 - 0.049 14.0 3.8 0.1 12.9 2.7 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein DNA_pol_viral_N PF00242.12 GAM22832.1 - 0.12 11.3 11.4 0.18 10.7 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF601 PF04642.7 GAM22832.1 - 0.5 9.6 25.5 0.77 9.0 17.7 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DDHD PF02862.12 GAM22832.1 - 1.3 8.7 15.7 2.3 7.9 10.9 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 GAM22832.1 - 3.4 5.6 16.3 4.9 5.0 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 GAM22832.1 - 5.1 5.5 12.8 10 4.5 8.9 1.4 1 0 0 1 1 1 0 Raftlin DUF2146 PF10220.4 GAM22832.1 - 5.3 4.8 11.8 7.7 4.3 8.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) ETRAMP PF09716.5 GAM22832.1 - 5.8 6.9 8.3 4e+02 1.0 5.7 2.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Macoilin PF09726.4 GAM22832.1 - 8 4.6 27.4 12 4.0 19.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DSPc PF00782.15 GAM22833.1 - 8.1e-35 119.3 1.7 1.4e-34 118.5 1.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM22833.1 - 1.7e-06 28.1 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Rhodanese PF00581.15 GAM22833.1 - 2.4e-06 27.8 0.0 0.0084 16.4 0.0 2.7 3 0 0 3 3 3 2 Rhodanese-like domain Y_phosphatase PF00102.22 GAM22833.1 - 7.2e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 GAM22833.1 - 0.029 13.8 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 GAM22833.1 - 0.033 14.4 0.1 0.27 11.4 0.1 2.3 2 1 0 2 2 2 0 Tyrosine phosphatase family Dor1 PF04124.7 GAM22834.1 - 0.0015 17.0 1.7 0.0016 16.9 0.3 1.6 2 0 0 2 2 2 1 Dor1-like family MscS_porin PF12795.2 GAM22834.1 - 0.05 12.9 4.6 0.092 12.0 3.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Hyccin PF09790.4 GAM22835.1 - 2e-33 115.5 0.1 2.6e-32 111.9 0.1 2.0 1 1 0 1 1 1 1 Hyccin DUF2360 PF10152.4 GAM22835.1 - 0.0009 19.5 0.3 1.1 9.5 0.1 2.2 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein (DUF2360) RasGAP PF00616.14 GAM22836.1 - 1.2e-43 149.0 0.9 1e-42 146.0 0.0 2.7 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase PPR_2 PF13041.1 GAM22837.1 - 2.9e-38 129.6 12.0 2.1e-08 34.0 0.0 8.2 5 3 2 8 8 8 7 PPR repeat family PPR_3 PF13812.1 GAM22837.1 - 7.5e-27 91.3 0.1 6.6e-05 22.8 0.0 9.0 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 GAM22837.1 - 3.9e-24 82.8 6.9 3.5e-08 32.8 0.1 6.8 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 GAM22837.1 - 6.5e-17 60.7 0.7 6.6e-05 22.3 0.0 6.4 6 0 0 6 6 6 4 PPR repeat TPR_19 PF14559.1 GAM22837.1 - 2.7e-05 24.4 0.0 1.2 9.5 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM22837.1 - 0.0027 17.7 3.4 3.6 7.7 0.0 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 GAM22837.1 - 0.017 15.4 0.0 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF1955 PF09205.5 GAM22837.1 - 0.1 12.1 0.0 0.1 12.1 0.0 3.1 4 1 1 5 5 5 0 Domain of unknown function (DUF1955) Aldedh PF00171.17 GAM22838.1 - 2.7e-119 398.5 0.0 3.3e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 GAM22838.1 - 1.4e-06 27.3 0.0 2.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) 2C_adapt PF08793.5 GAM22838.1 - 0.9 9.4 2.4 0.83 9.5 0.1 2.1 3 0 0 3 3 3 0 2-cysteine adaptor domain Not1 PF04054.10 GAM22840.1 - 1.8e-139 464.8 6.3 1.8e-139 464.8 4.3 3.5 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 GAM22840.1 - 1.6e-52 177.0 0.3 7e-52 175.0 0.2 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Dehyd-heme_bind PF09098.5 GAM22840.1 - 0.029 13.8 1.2 0.21 11.0 0.3 2.2 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding DLL_N PF12413.3 GAM22840.1 - 3.9 8.5 19.5 0.03 15.3 2.6 3.4 3 0 0 3 3 3 0 Homeobox protein distal-less-like N terminal ADH_zinc_N PF00107.21 GAM22841.1 - 3.5e-25 88.0 0.1 1.6e-24 85.8 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM22841.1 - 1.1e-13 50.9 0.0 2.9e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM22841.1 - 6.8e-09 36.6 0.0 3.7e-08 34.3 0.0 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 GAM22841.1 - 0.0036 16.8 0.5 0.0096 15.5 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.20 GAM22841.1 - 0.017 14.4 0.3 0.029 13.5 0.2 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.3 GAM22841.1 - 0.071 12.9 0.7 0.19 11.5 0.5 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rad52_Rad22 PF04098.10 GAM22842.1 - 3.1e-28 98.4 0.0 5.1e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Serglycin PF04360.7 GAM22842.1 - 0.021 14.5 5.0 0.035 13.8 3.5 1.3 1 0 0 1 1 1 0 Serglycin Period_C PF12114.3 GAM22842.1 - 3.7 7.0 8.5 9.7 5.7 5.9 1.7 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Metallophos PF00149.23 GAM22843.1 - 1.7e-17 63.4 0.9 3.9e-17 62.3 0.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM22843.1 - 1e-13 51.3 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 GAM22843.1 - 0.0066 15.6 0.2 0.015 14.4 0.1 1.6 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Lactamase_B_2 PF12706.2 GAM22843.1 - 0.013 15.0 0.5 0.31 10.5 0.1 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain DUF2340 PF10209.4 GAM22844.1 - 8.4e-43 145.4 1.5 1e-42 145.1 1.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DENN PF02141.16 GAM22845.1 - 8.5e-50 169.0 3.4 8.5e-50 169.0 2.3 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 GAM22845.1 - 3.2e-13 49.4 1.0 8.3e-13 48.1 0.2 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.14 GAM22845.1 - 3.3e-13 49.4 5.5 1.1e-12 47.8 3.8 2.0 1 0 0 1 1 1 1 dDENN domain CBS PF00571.23 GAM22846.1 - 1.7e-41 139.7 1.2 3e-13 49.3 0.1 4.1 4 0 0 4 4 4 4 CBS domain Recep_L_domain PF01030.19 GAM22846.1 - 0.067 13.1 1.7 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Receptor L domain SporV_AA PF12164.3 GAM22846.1 - 2.1 8.3 6.7 2.7 8.0 0.4 3.2 2 1 2 4 4 4 0 Stage V sporulation protein AA IFRD PF05004.8 GAM22847.1 - 6.1e-08 32.0 8.8 9.8e-07 28.1 6.1 2.4 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF2201_N PF13203.1 GAM22847.1 - 0.021 14.0 3.1 0.032 13.3 2.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain BUD22 PF09073.5 GAM22847.1 - 0.24 10.4 16.1 0.37 9.8 11.2 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 GAM22847.1 - 1 7.1 20.4 1.5 6.6 14.1 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 GAM22847.1 - 1.1 7.4 5.3 1.4 7.0 3.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 GAM22847.1 - 1.7 7.9 13.8 3.4 6.9 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1212 PF06738.7 GAM22848.1 - 6.6e-43 146.4 11.6 4.9e-37 127.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 GAM22848.1 - 2.9e-14 53.0 37.0 1.6e-12 47.5 9.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Myb_DNA-binding PF00249.26 GAM22849.1 - 3e-06 27.1 0.1 6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1510 PF07423.6 GAM22849.1 - 0.13 11.5 26.6 0.074 12.4 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Gag_spuma PF03276.9 GAM22849.1 - 5.6 5.1 19.6 0.016 13.5 5.9 1.9 2 0 0 2 2 2 0 Spumavirus gag protein Sel1 PF08238.7 GAM22850.1 - 2.2e-52 174.3 49.0 2.5e-07 31.1 0.2 12.5 13 0 0 13 13 13 10 Sel1 repeat TPR_11 PF13414.1 GAM22850.1 - 0.052 13.1 25.8 0.85 9.3 0.7 6.1 4 2 1 5 5 5 0 TPR repeat Antimicrobial17 PF08129.6 GAM22850.1 - 0.065 13.0 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta enterocin family MIT PF04212.13 GAM22850.1 - 0.39 10.6 6.1 11 5.9 0.1 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Spt20 PF12090.3 GAM22850.1 - 0.52 9.6 5.3 1.1 8.5 3.7 1.6 1 0 0 1 1 1 0 Spt20 family TPR_14 PF13428.1 GAM22850.1 - 0.64 10.8 5.7 34 5.4 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat B-block_TFIIIC PF04182.7 GAM22852.1 - 9.9e-15 54.1 7.4 4.7e-12 45.5 0.7 5.3 6 0 0 6 6 6 2 B-block binding subunit of TFIIIC HTH_24 PF13412.1 GAM22852.1 - 3.1e-06 26.4 0.5 11 5.4 0.0 6.1 7 0 0 7 7 7 3 Winged helix-turn-helix DNA-binding MarR PF01047.17 GAM22852.1 - 0.0016 18.0 0.2 9.4 6.0 0.0 3.9 3 0 0 3 3 3 2 MarR family Myb_DNA-binding PF00249.26 GAM22852.1 - 0.1 12.6 0.8 2.2 8.4 0.5 2.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain DNA_pol_A_exo1 PF01612.15 GAM22853.1 - 0.00097 18.6 0.1 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Tup_N PF08581.5 GAM22853.1 - 0.15 12.2 0.7 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Tup N-terminal TrkH PF02386.11 GAM22854.1 - 0.11 11.0 1.8 0.17 10.4 1.0 1.3 1 1 0 1 1 1 0 Cation transport protein Sugar_tr PF00083.19 GAM22854.1 - 0.66 8.4 1.7 0.52 8.8 0.2 1.5 1 1 1 2 2 2 0 Sugar (and other) transporter NUDIX PF00293.23 GAM22855.1 - 1.8e-13 50.2 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Vps5 PF09325.5 GAM22857.1 - 1.4e-54 184.8 5.0 1.4e-54 184.8 3.5 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 GAM22857.1 - 8.1e-24 83.6 0.3 2.6e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 PX domain BAR PF03114.13 GAM22857.1 - 0.00012 21.6 3.3 0.00012 21.6 2.3 2.0 2 0 0 2 2 2 1 BAR domain Uds1 PF15456.1 GAM22857.1 - 0.75 9.8 8.2 0.049 13.6 1.3 2.2 3 0 0 3 3 3 0 Up-regulated During Septation MinC_N PF05209.8 GAM22858.1 - 5.5e-05 22.8 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain MinC_C PF03775.11 GAM22859.1 - 4.6e-30 103.3 0.1 6.3e-30 102.9 0.0 1.2 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain DUF342 PF03961.8 GAM22859.1 - 0.0033 15.9 0.3 0.0043 15.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Sporozoite_P67 PF05642.6 GAM22859.1 - 4.6 4.9 9.4 5.6 4.6 6.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GyrI-like PF06445.10 GAM22860.1 - 2.9e-29 102.0 0.2 3.3e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 GyrI-like small molecule binding domain Cass2 PF14526.1 GAM22860.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Integron-associated effector binding protein SOUL PF04832.7 GAM22860.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 SOUL heme-binding protein Solute_trans_a PF03619.11 GAM22861.1 - 9.6e-38 130.0 6.7 1.3e-37 129.6 4.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Radical_SAM PF04055.16 GAM22862.1 - 3.6e-17 63.0 0.0 1.2e-16 61.3 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 GAM22862.1 - 4.2e-13 49.1 0.0 9.1e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM22862.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 GAM22862.1 - 0.024 14.7 0.1 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPT PF03151.11 GAM22863.1 - 8.9e-20 70.8 10.3 8.9e-20 70.8 7.1 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAM22863.1 - 4.1e-08 32.5 28.6 5.6e-08 32.0 19.8 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 GAM22863.1 - 1.6e-07 31.4 40.0 5.6e-05 23.1 10.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family IncA PF04156.9 GAM22863.1 - 0.4 10.2 0.0 0.4 10.2 0.0 2.9 4 0 0 4 4 4 0 IncA protein 7TMR-DISM_7TM PF07695.6 GAM22863.1 - 0.78 9.3 49.3 0.16 11.6 10.4 2.6 1 1 0 2 2 2 0 7TM diverse intracellular signalling DUF2681 PF10883.3 GAM22863.1 - 4 7.7 11.9 0.14 12.3 2.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Fra10Ac1 PF09725.4 GAM22864.1 - 2.5e-34 117.8 0.9 4.5e-34 117.0 0.6 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 E6 PF00518.12 GAM22864.1 - 0.019 15.3 2.0 0.025 14.9 1.4 1.2 1 0 0 1 1 1 0 Early Protein (E6) PBP1_TM PF14812.1 GAM22864.1 - 3.6 7.9 23.2 1.1 9.6 6.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNARE_assoc PF09335.6 GAM22865.1 - 4e-05 23.7 3.9 0.00047 20.3 1.2 3.2 3 1 0 3 3 3 1 SNARE associated Golgi protein TFIID-18kDa PF02269.11 GAM22865.1 - 0.13 12.1 0.3 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TUG-UBL1 PF11470.3 GAM22866.1 - 0.00076 19.3 0.1 0.005 16.7 0.0 2.4 2 0 0 2 2 2 1 GLUT4 regulating protein TUG FERM_N PF09379.5 GAM22866.1 - 0.00077 19.4 0.1 0.0038 17.2 0.0 2.2 2 0 0 2 2 2 1 FERM N-terminal domain RhoGEF PF00621.15 GAM22867.1 - 3.2e-39 134.6 6.2 5.7e-39 133.8 4.3 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM22867.1 - 0.042 14.0 0.1 0.16 12.2 0.1 2.0 1 0 0 1 1 1 0 PH domain NAD_binding_4 PF07993.7 GAM22868.1 - 4.7e-54 182.9 0.0 7.3e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM22868.1 - 1.4e-34 119.2 0.0 2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM22868.1 - 1.5e-11 44.1 0.0 3.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM22868.1 - 4.2e-05 22.4 0.6 0.00011 20.9 0.4 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 GAM22868.1 - 6.1e-05 23.2 0.1 0.00027 21.1 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 GAM22868.1 - 0.0034 16.3 0.0 0.25 10.1 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM22868.1 - 0.007 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM22868.1 - 0.027 14.5 0.0 1 9.3 0.0 2.4 1 1 0 1 1 1 0 NADH(P)-binding DDE_2 PF02914.10 GAM22868.1 - 0.037 13.5 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage Mu transposase NAD_binding_4 PF07993.7 GAM22869.1 - 6.1e-55 185.8 0.0 8.4e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 GAM22869.1 - 1.8e-44 151.8 0.0 3e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 GAM22869.1 - 1e-10 41.5 0.0 2.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM22869.1 - 5.8e-08 31.7 0.0 1.5e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM22869.1 - 0.00025 20.0 0.1 0.032 13.1 0.0 3.0 2 1 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.20 GAM22869.1 - 0.0085 16.3 0.1 0.025 14.8 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 GAM22869.1 - 0.056 12.3 0.0 0.13 11.1 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein FNIP PF05725.7 GAM22870.1 - 1.4e-79 261.8 21.7 4.9e-10 39.1 0.0 9.3 6 2 0 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 GAM22870.1 - 1.6e-06 27.9 0.8 3.3 7.7 0.0 6.8 6 1 1 7 7 7 2 Protein of unknown function (DUF1769) CTK3 PF12243.3 GAM22873.1 - 3e-16 59.2 0.8 6.3e-16 58.2 0.5 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.8 GAM22873.1 - 5.5e-10 39.3 0.2 1.8e-09 37.7 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CpXC PF14353.1 GAM22873.1 - 0.46 10.4 0.0 0.46 10.4 0.0 3.6 3 1 1 4 4 4 0 CpXC protein Zip PF02535.17 GAM22873.1 - 3.5 6.5 5.0 5.8 5.8 3.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter LINES_N PF14694.1 GAM22874.1 - 3.8e-12 46.1 5.0 5.6e-12 45.5 1.5 2.4 2 0 0 2 2 2 1 Lines N-terminus LINES_C PF14695.1 GAM22874.1 - 8.7e-07 28.0 0.6 0.0004 19.5 0.1 2.9 2 0 0 2 2 2 2 Lines C-terminus FUSC_2 PF13515.1 GAM22875.1 - 0.00082 19.2 12.6 0.0011 18.8 8.4 1.5 1 1 0 1 1 1 1 Fusaric acid resistance protein-like DUF3021 PF11457.3 GAM22875.1 - 0.16 11.8 20.7 0.027 14.3 11.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) DUF4389 PF14333.1 GAM22875.1 - 4.1 7.1 9.8 0.33 10.6 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4389) FUSC_2 PF13515.1 GAM22876.1 - 1.7e-12 47.3 14.1 1.7e-12 47.3 9.8 1.7 1 1 0 1 1 1 1 Fusaric acid resistance protein-like ALMT PF11744.3 GAM22876.1 - 6.4e-12 44.8 6.1 1.2e-11 43.9 4.2 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC PF04632.7 GAM22876.1 - 3.8e-07 28.9 0.0 5.5e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family ER PF01133.12 GAM22876.1 - 0.066 12.9 1.6 0.12 12.0 0.2 2.1 2 0 0 2 2 2 0 Enhancer of rudimentary ORC2 PF04084.9 GAM22877.1 - 6.7e-79 265.0 1.2 9.1e-79 264.6 0.8 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Rox3 PF08633.5 GAM22877.1 - 2.5 8.3 8.8 16 5.7 2.6 2.2 2 0 0 2 2 2 0 Rox3 mediator complex subunit RhoGAP PF00620.22 GAM22878.1 - 6.1e-13 48.6 0.1 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M73 PF12389.3 GAM22879.1 - 0.0013 18.2 0.6 0.017 14.6 0.1 2.2 2 0 0 2 2 2 1 Camelysin metallo-endopeptidase TGS PF02824.16 GAM22879.1 - 0.078 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 TGS domain DUF2088 PF09861.4 GAM22879.1 - 0.16 10.9 4.1 0.063 12.2 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2088) DUF2894 PF11445.3 GAM22879.1 - 0.35 11.1 5.0 2.8 8.1 2.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) DNA_pol_B_3 PF08408.5 GAM22879.1 - 1.1 9.0 5.9 0.54 10.1 0.9 2.4 2 0 0 2 2 2 0 DNA polymerase family B viral insert ECH_C PF13766.1 GAM22880.1 - 2.5e-38 130.8 0.0 3.8e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 GAM22880.1 - 1e-25 90.3 0.0 2.5e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TPT PF03151.11 GAM22881.1 - 1.8e-10 40.6 9.4 1.8e-10 40.6 6.5 2.9 1 1 1 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAM22881.1 - 4.2e-05 22.6 34.2 0.011 14.6 9.4 3.0 1 1 2 3 3 3 3 UAA transporter family CCSMST1 PF15013.1 GAM22881.1 - 0.059 13.2 3.2 2.2 8.2 0.1 2.8 2 0 0 2 2 2 0 CCSMST1 family EamA PF00892.15 GAM22881.1 - 0.079 13.0 26.7 0.91 9.5 6.2 2.2 1 1 1 2 2 2 0 EamA-like transporter family Lipoprotein_17 PF04200.7 GAM22881.1 - 0.13 12.4 2.4 0.27 11.3 1.7 1.6 1 0 0 1 1 1 0 Lipoprotein associated domain Band_3_cyto PF07565.8 GAM22881.1 - 1.1 8.7 7.8 2 7.8 5.4 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain UDPGP PF01704.13 GAM22882.1 - 3.3e-169 562.8 0.6 3.8e-169 562.6 0.4 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 GAM22882.1 - 0.026 13.0 0.3 0.14 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) NST1 PF13945.1 GAM22883.1 - 9.3e-45 153.0 15.3 9.3e-45 153.0 10.6 6.2 3 2 2 6 6 6 1 Salt tolerance down-regulator tRNA-synt_2 PF00152.15 GAM22884.1 - 1e-79 267.7 0.3 1.3e-79 267.4 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM22884.1 - 7.6e-10 38.5 0.7 1.7e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain HGD-D PF06050.8 GAM22884.1 - 0.004 16.0 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component tRNA-synt_2d PF01409.15 GAM22884.1 - 0.03 13.5 0.0 0.42 9.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Neuropeptide_S PF14993.1 GAM22885.1 - 0.044 13.4 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Neuropeptide S precursor protein DUF1273 PF06908.6 GAM22886.1 - 0.0086 15.7 0.4 0.013 15.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1273) SR-25 PF10500.4 GAM22886.1 - 0.017 14.6 4.1 0.022 14.2 2.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.14 GAM22886.1 - 0.067 12.9 8.4 0.092 12.5 5.8 1.1 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.20 GAM22887.1 - 9.8e-73 244.4 0.0 1.2e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22887.1 - 7.7e-35 120.2 0.0 1e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 GAM22887.1 - 6.8e-22 77.6 0.3 1.4e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM22887.1 - 2.1e-10 40.8 2.7 5.4e-09 36.2 1.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM22887.1 - 3.5e-07 30.1 0.2 7.7e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.19 GAM22887.1 - 4.3e-06 27.1 0.5 8.4e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM22887.1 - 0.00066 18.7 0.0 0.0022 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH_6 PF15406.1 GAM22887.1 - 0.0052 16.8 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 GAM22887.1 - 0.0085 15.8 0.0 0.02 14.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family PH_9 PF15410.1 GAM22887.1 - 0.023 14.8 0.6 0.29 11.2 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain Phosphorylase PF00343.15 GAM22888.1 - 0 1156.0 4.2 0 1155.7 2.9 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase PCI PF01399.22 GAM22889.1 - 8.5e-22 77.4 2.7 2.1e-21 76.1 0.1 2.6 2 1 0 2 2 2 1 PCI domain ERp29 PF07749.7 GAM22889.1 - 0.82 10.3 8.4 0.63 10.6 0.4 3.7 2 1 2 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain G-alpha PF00503.15 GAM22890.1 - 3.5e-102 342.0 2.1 4.3e-102 341.7 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM22890.1 - 6e-14 51.6 0.1 7.9e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM22890.1 - 0.0018 17.4 2.0 0.15 11.1 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM22890.1 - 0.0056 16.6 0.1 3.1 7.7 0.0 3.2 2 1 2 4 4 4 1 50S ribosome-binding GTPase Miro PF08477.8 GAM22890.1 - 0.012 16.0 1.1 1.3 9.5 0.3 2.8 2 1 1 3 3 3 0 Miro-like protein AAA_29 PF13555.1 GAM22890.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spo0M PF07070.6 GAM22890.1 - 0.079 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein AAA_17 PF13207.1 GAM22890.1 - 0.092 13.5 0.4 0.44 11.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM22890.1 - 0.15 11.9 3.8 0.51 10.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain zf-4CXXC_R1 PF10497.4 GAM22891.1 - 0.1 12.7 7.3 0.48 10.5 5.0 2.2 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF1786 PF08735.5 GAM22891.1 - 0.1 11.7 1.4 4.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) PAT1 PF09770.4 GAM22891.1 - 3.9 5.5 30.6 0.06 11.5 14.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 K_channel_TID PF07941.6 GAM22891.1 - 4.5 7.5 7.2 0.37 11.0 1.3 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Ibs_toxin PF13956.1 GAM22893.1 - 0.14 11.9 0.9 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Sugarporin_N PF11471.3 GAM22893.1 - 0.2 11.2 2.3 1.9 8.1 1.6 2.1 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ctf8 PF09696.5 GAM22894.1 - 5.9e-11 42.2 2.4 4.2e-10 39.4 1.6 2.2 1 1 0 1 1 1 1 Ctf8 TFIIF_alpha PF05793.7 GAM22894.1 - 1 7.6 8.8 1.3 7.2 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bromodomain PF00439.20 GAM22895.1 - 6.9e-17 61.1 0.1 1.8e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 GAM22895.1 - 3.4e-06 26.6 5.1 1.5e-05 24.5 3.5 2.3 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAM22895.1 - 0.00047 19.4 1.7 0.00047 19.4 1.2 2.2 2 0 0 2 2 2 1 PHD-finger DUF3573 PF12097.3 GAM22895.1 - 0.3 9.6 6.2 0.57 8.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Zip PF02535.17 GAM22895.1 - 1 8.2 8.4 1.7 7.5 5.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Cauli_AT PF03233.8 GAM22895.1 - 4.7 6.8 7.4 1.8 8.2 2.1 2.3 2 0 0 2 2 2 0 Aphid transmission protein G6PD_C PF02781.11 GAM22896.1 - 1.3e-121 404.9 0.0 1.8e-121 404.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 GAM22896.1 - 9e-57 192.2 0.1 1.5e-56 191.5 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GSIII_N PF12437.3 GAM22897.1 - 1.3e-72 242.5 0.0 2.3e-72 241.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 GAM22897.1 - 2.2e-39 135.1 0.0 4.7e-39 134.1 0.0 1.5 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain AATase PF07247.7 GAM22898.1 - 2.8e-23 82.2 0.0 3.6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAM22898.1 - 3.9e-11 42.3 1.2 5.8e-09 35.2 0.4 2.2 2 0 0 2 2 2 2 Condensation domain CUE PF02845.11 GAM22899.1 - 5.8e-08 32.0 0.1 1.4e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 CUE domain DUF3439 PF11921.3 GAM22899.1 - 1.6 8.4 28.1 2.2 8.0 6.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Tmpp129 PF10272.4 GAM22900.1 - 2.2e-06 26.6 16.8 5.7e-06 25.2 11.6 1.7 1 1 0 1 1 1 1 Putative transmembrane protein precursor IncA PF04156.9 GAM22900.1 - 0.039 13.5 15.6 0.071 12.7 3.0 2.2 2 0 0 2 2 2 0 IncA protein Rtf2 PF04641.7 GAM22900.1 - 1.6 7.9 19.9 0.036 13.2 8.9 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger Presenilin PF01080.12 GAM22900.1 - 5.8 5.6 10.3 9.7 4.8 7.1 1.5 1 0 0 1 1 1 0 Presenilin PGAP1 PF07819.8 GAM22901.1 - 1.5e-68 230.7 0.0 2.5e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 GAM22901.1 - 0.0079 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM22901.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM22901.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold polyprenyl_synt PF00348.12 GAM22902.1 - 1.7e-53 181.1 0.2 1.7e-53 181.1 0.2 1.4 2 0 0 2 2 2 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 GAM22902.1 - 0.021 14.2 0.1 0.021 14.2 0.1 1.8 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pkinase_Tyr PF07714.12 GAM22903.1 - 1.9e-61 207.4 0.0 3.6e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM22903.1 - 3.4e-53 180.4 0.0 3.4e-53 180.4 0.0 2.4 3 1 0 3 3 2 1 Protein kinase domain SH2 PF00017.19 GAM22903.1 - 6.9e-12 44.9 0.0 6.9e-12 44.9 0.0 2.2 2 0 0 2 2 1 1 SH2 domain Spore_coat_CotO PF14153.1 GAM22903.1 - 0.028 13.8 15.9 0.049 13.0 11.0 1.4 1 0 0 1 1 1 0 Spore coat protein CotO APH PF01636.18 GAM22903.1 - 0.036 13.7 0.0 0.036 13.7 0.0 2.4 3 0 0 3 3 2 0 Phosphotransferase enzyme family Mem_trans PF03547.13 GAM22903.1 - 0.084 11.1 1.8 0.12 10.6 1.2 1.3 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.11 GAM22903.1 - 0.78 9.5 13.7 1.3 8.8 9.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 GAM22903.1 - 1.1 7.3 46.8 1.7 6.7 32.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 GAM22903.1 - 1.1 7.1 12.4 1.6 6.7 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 GAM22903.1 - 2.3 7.9 32.2 5.4 6.8 22.3 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.1 GAM22903.1 - 4.3 7.0 12.4 8.4 6.0 8.6 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Ank_4 PF13637.1 GAM22904.1 - 4.6e-52 173.5 9.9 1.1e-12 48.0 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM22904.1 - 2.3e-44 147.0 0.5 9.7e-10 37.7 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 GAM22904.1 - 9.2e-44 147.6 0.0 9e-17 61.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM22904.1 - 6.4e-40 134.2 5.1 6.1e-11 42.1 0.0 4.9 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22904.1 - 1.1e-36 121.1 0.4 3.7e-08 32.8 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 GAM22904.1 - 4.1e-31 107.6 8.5 4.1e-31 107.6 5.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Secretin_N_2 PF07655.8 GAM22904.1 - 1.8 8.9 10.3 4.8 7.6 7.1 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain CAF1 PF04857.15 GAM22906.1 - 2.1e-50 171.5 10.0 4.7e-50 170.3 6.9 1.6 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 GAM22906.1 - 0.00026 20.5 0.1 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 3'-5' exonuclease zf-CCCH PF00642.19 GAM22906.1 - 0.069 12.8 0.3 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Myosin_head PF00063.16 GAM22908.1 - 1.2e-263 876.2 2.8 1.5e-263 875.9 2.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM22908.1 - 3e-50 170.2 4.7 5.1e-50 169.5 3.2 1.4 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 GAM22908.1 - 1.2e-09 36.9 5.5 0.00083 18.7 0.0 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 GAM22908.1 - 0.014 15.5 0.0 0.05 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 GAM22908.1 - 0.023 13.7 0.2 0.058 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 GAM22908.1 - 0.033 14.9 0.8 0.31 11.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 GAM22908.1 - 0.052 13.8 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 GAM22908.1 - 0.058 12.2 0.1 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 GAM22908.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Notch PF00066.12 GAM22910.1 - 1.5e-47 159.5 107.6 2.5e-09 37.2 5.0 7.4 7 1 0 7 7 7 6 LNR domain TMEM154 PF15102.1 GAM22911.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 GAM22911.1 - 0.022 15.1 2.5 0.041 14.2 1.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.1 GAM22911.1 - 0.025 14.0 0.1 0.078 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1191 PF06697.7 GAM22911.1 - 0.043 12.6 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PulG PF11773.3 GAM22911.1 - 0.084 12.6 0.5 0.084 12.6 0.3 1.7 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF912 PF06024.7 GAM22911.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CD34_antigen PF06365.7 GAM22911.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Herpes_gE PF02480.11 GAM22911.1 - 0.13 10.5 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 GAM22911.1 - 0.13 11.8 0.5 0.2 11.2 0.3 1.2 1 0 0 1 1 1 0 Protocadherin Baculo_11_kDa PF06143.6 GAM22911.1 - 0.55 9.6 4.4 0.16 11.3 0.8 1.8 2 0 0 2 2 2 0 Baculovirus 11 kDa family Rifin_STEVOR PF02009.11 GAM22911.1 - 1.6 8.3 3.8 2.5 7.6 2.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family UPF0556 PF10572.4 GAM22912.1 - 3e-21 75.2 0.0 3.4e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 ADK_lid PF05191.9 GAM22913.1 - 0.0013 18.3 0.1 0.002 17.7 0.1 1.2 1 0 0 1 1 1 1 Adenylate kinase, active site lid RRM_6 PF14259.1 GAM22914.1 - 0.002 18.0 0.0 0.012 15.6 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22914.1 - 0.034 13.9 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM22914.1 - 0.073 12.7 0.0 1.1 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3Ka PF00613.15 GAM22915.1 - 2.7e-25 88.5 3.4 1.9e-23 82.6 1.7 2.7 1 1 1 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM22915.1 - 1.3e-17 64.0 0.3 1.3e-17 64.0 0.2 2.9 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.16 GAM22915.1 - 2.2e-15 56.2 8.7 7.1e-15 54.6 6.0 1.9 1 0 0 1 1 1 1 FYVE zinc finger DUF4615 PF15393.1 GAM22916.1 - 3.2e-10 40.3 12.8 3.2e-10 40.3 8.9 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4615) Asp_Arg_Hydrox PF05118.10 GAM22916.1 - 0.019 14.8 2.8 0.039 13.7 1.9 1.5 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase SSP160 PF06933.6 GAM22916.1 - 0.5 8.2 8.3 0.6 8.0 5.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 UQ_con PF00179.21 GAM22917.1 - 1.7e-45 153.8 0.1 9.5e-45 151.4 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme TPR_11 PF13414.1 GAM22918.1 - 1.4e-22 79.0 9.7 6.3e-15 54.5 1.8 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM22918.1 - 4.6e-18 63.9 6.0 3.5e-07 29.5 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM22918.1 - 5e-14 51.0 5.5 5.1e-06 26.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM22918.1 - 1.3e-12 46.5 4.6 2.3e-05 23.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM22918.1 - 1.2e-11 43.8 8.9 0.0001 22.1 0.9 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM22918.1 - 1.6e-08 34.4 0.1 0.0024 18.3 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM22918.1 - 1.5e-07 31.6 2.1 3.8e-06 27.1 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM22918.1 - 3.4e-07 30.7 2.0 8.6e-07 29.4 1.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM22918.1 - 4.6e-07 29.6 0.4 1.6e-06 27.9 0.4 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM22918.1 - 2.3e-06 26.9 1.2 0.033 13.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM22918.1 - 4.5e-06 26.7 2.9 0.006 16.9 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat DUF3856 PF12968.2 GAM22918.1 - 0.0045 16.8 3.6 0.044 13.5 1.1 2.7 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) FAT PF02259.18 GAM22918.1 - 0.012 14.6 0.3 0.024 13.6 0.1 1.5 1 1 0 1 1 1 0 FAT domain TPR_15 PF13429.1 GAM22918.1 - 0.013 14.5 0.3 0.021 13.9 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM22918.1 - 0.014 15.4 3.4 0.032 14.3 2.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Duffy_binding PF05424.6 GAM22918.1 - 0.017 14.9 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Duffy binding domain TPR_20 PF14561.1 GAM22918.1 - 0.098 12.7 0.9 0.67 10.1 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat XPC-binding PF09280.6 GAM22918.1 - 0.79 9.2 7.3 3.2 7.2 0.9 2.7 1 1 1 2 2 2 0 XPC-binding domain TPR_14 PF13428.1 GAM22919.1 - 6.3e-10 38.8 11.0 1.5 9.6 0.0 8.1 6 3 3 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM22919.1 - 2e-08 33.7 4.4 0.12 12.0 0.0 5.4 5 0 0 5 5 5 3 TPR repeat TPR_19 PF14559.1 GAM22919.1 - 6.3e-08 32.8 9.0 0.13 12.6 0.0 6.8 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM22919.1 - 1.2e-06 29.0 8.1 0.69 10.6 0.0 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM22919.1 - 0.0006 19.8 0.1 0.25 11.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 GAM22919.1 - 0.0076 16.0 0.3 0.0076 16.0 0.2 8.7 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 GAM22919.1 - 0.011 15.5 19.6 1 9.4 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM22919.1 - 2.2 8.2 18.7 3.9 7.4 0.1 6.9 7 1 1 8 8 8 0 Tetratricopeptide repeat GRIM-19 PF06212.7 GAM22921.1 - 2.3e-15 56.4 0.0 7.2e-15 54.8 0.0 1.7 1 1 1 2 2 2 1 GRIM-19 protein SAYSvFN PF10260.4 GAM22921.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) Coiled PF05710.7 GAM22922.1 - 0.00041 20.7 6.7 0.00052 20.4 4.6 1.2 1 0 0 1 1 1 1 Coiled coil Phosphonate-bd PF12974.2 GAM22923.1 - 3.1e-23 82.4 0.0 4.7e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 GAM22923.1 - 0.0035 16.9 0.0 0.0094 15.5 0.0 1.7 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 GAM22923.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 WD40 PF00400.27 GAM22924.1 - 1.8e-62 205.1 9.0 4.5e-10 39.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 GAM22924.1 - 0.00014 21.1 0.3 1.2 8.1 0.0 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 GAM22924.1 - 0.0095 14.1 2.4 0.37 8.8 0.3 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 GAM22924.1 - 0.088 11.0 0.0 0.91 7.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) EGF_2 PF07974.8 GAM22925.1 - 0.00076 19.5 16.1 0.00076 19.5 11.1 2.2 3 0 0 3 3 3 1 EGF-like domain EB PF01683.13 GAM22925.1 - 0.0025 17.8 4.8 0.006 16.6 3.3 1.6 1 0 0 1 1 1 1 EB module DUF1191 PF06697.7 GAM22925.1 - 0.0037 16.1 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) TMEM154 PF15102.1 GAM22925.1 - 0.013 15.2 0.4 0.047 13.4 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family Protocadherin PF08374.6 GAM22925.1 - 0.11 12.0 1.1 0.2 11.2 0.8 1.3 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 GAM22925.1 - 0.16 12.4 2.5 0.21 12.0 0.9 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_5 PF12695.2 GAM22926.1 - 2.5e-23 82.4 0.0 5.2e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM22926.1 - 1.1e-17 64.6 0.0 3.8e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM22926.1 - 3.3e-13 49.7 0.0 6.2e-08 32.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM22926.1 - 1.2e-10 41.1 0.0 5.3e-06 26.0 0.0 3.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM22926.1 - 1.1e-09 37.8 0.0 4.5e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 GAM22926.1 - 3.1e-08 32.4 0.1 0.0017 16.9 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 GAM22926.1 - 9.5e-08 31.5 0.0 4.7e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.7 GAM22926.1 - 6.3e-07 28.4 0.0 8.6e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 GAM22926.1 - 5e-06 26.3 0.0 0.027 14.2 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 GAM22926.1 - 0.00039 20.0 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 GAM22926.1 - 0.0009 18.7 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase PF00756.15 GAM22926.1 - 0.0014 18.1 0.0 0.0039 16.6 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 GAM22926.1 - 0.0026 17.0 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_4 PF08386.5 GAM22926.1 - 0.0032 17.3 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Lipase_3 PF01764.20 GAM22926.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S28 PF05577.7 GAM22926.1 - 0.02 13.4 0.0 0.045 12.3 0.0 1.4 1 1 0 1 1 1 0 Serine carboxypeptidase S28 GSu_C4xC__C2xCH PF09698.5 GAM22926.1 - 0.023 14.8 0.2 0.04 14.0 0.2 1.4 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) PGAP1 PF07819.8 GAM22926.1 - 0.058 12.9 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 GAM22926.1 - 0.086 12.6 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Sterol_MT_C PF08498.5 GAM22927.1 - 1.1e-19 70.1 0.0 1.9e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 GAM22927.1 - 2.5e-17 63.1 0.0 5.3e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM22927.1 - 1.6e-15 56.9 0.0 2.9e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 GAM22927.1 - 1.2e-14 54.1 0.0 1.9e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM22927.1 - 6.3e-14 51.9 0.0 9.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM22927.1 - 5.5e-11 42.7 0.1 1.4e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM22927.1 - 2.6e-08 34.4 0.0 9.5e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM22927.1 - 2.9e-07 30.8 0.0 7.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM22927.1 - 1.2e-05 24.5 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 GAM22927.1 - 3.4e-05 23.4 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAM22927.1 - 4.4e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM22927.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.5 GAM22927.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CHCH PF06747.8 GAM22928.1 - 9.8e-06 25.3 4.4 1.4e-05 24.8 3.0 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 GAM22928.1 - 0.021 14.8 1.5 0.035 14.1 1.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 GAM22928.1 - 0.063 13.2 0.8 0.24 11.4 0.5 1.9 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb PCI PF01399.22 GAM22929.1 - 5.7e-25 87.6 3.1 8.4e-25 87.1 0.6 2.5 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 GAM22929.1 - 6.8e-14 51.8 0.9 2.1e-13 50.2 0.4 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 GAM22929.1 - 0.00096 18.7 1.8 15 5.6 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM22929.1 - 0.0027 17.6 1.2 1.3 8.9 0.0 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM22929.1 - 0.012 15.2 3.2 0.52 10.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM22929.1 - 0.015 14.9 1.4 3.1 7.5 0.0 4.2 3 2 1 4 4 4 0 TPR repeat DCD PF06559.6 GAM22929.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) TPR_2 PF07719.12 GAM22929.1 - 0.22 11.5 4.3 4 7.5 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM22929.1 - 0.46 10.3 16.0 0.44 10.4 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2457 PF10446.4 GAM22929.1 - 1.1 7.9 9.0 1.5 7.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRM_1 PF00076.17 GAM22930.1 - 3.4e-12 45.8 0.0 5.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM22930.1 - 3.9e-12 45.9 0.1 7.6e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM22930.1 - 1.2e-07 31.4 0.1 1.9e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 GAM22931.1 - 2.6e-60 203.7 0.0 5.1e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22931.1 - 6.2e-40 136.8 0.0 9.4e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM22931.1 - 0.0099 14.8 0.0 0.028 13.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DUF3419 PF11899.3 GAM22932.1 - 5.2e-14 51.7 0.1 6.9e-13 48.0 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_12 PF08242.7 GAM22932.1 - 0.0015 18.9 0.0 0.2 12.1 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM22932.1 - 0.0039 16.9 0.1 0.0056 16.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM22932.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain AAA_assoc_C PF09821.4 GAM22932.1 - 0.034 14.4 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 C-terminal AAA-associated domain PBS_linker_poly PF00427.16 GAM22932.1 - 0.036 13.7 0.5 1.8 8.2 0.0 3.1 2 1 1 3 3 3 0 Phycobilisome Linker polypeptide CheR PF01739.13 GAM22932.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 GAM22932.1 - 0.073 13.6 0.1 2.4 8.7 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain WW PF00397.21 GAM22933.1 - 3.5e-18 65.1 5.5 1.8e-10 40.4 0.2 2.5 2 0 0 2 2 2 2 WW domain Arm PF00514.18 GAM22933.1 - 1.3e-17 62.9 50.4 0.00051 19.7 0.2 16.4 17 0 0 17 17 17 5 Armadillo/beta-catenin-like repeat FYVE PF01363.16 GAM22933.1 - 1.3e-13 50.5 11.1 3.5e-13 49.2 7.7 1.8 1 0 0 1 1 1 1 FYVE zinc finger HEAT_2 PF13646.1 GAM22933.1 - 2.2e-09 37.4 15.5 0.024 14.8 0.0 9.0 8 2 1 9 9 9 3 HEAT repeats HEAT PF02985.17 GAM22933.1 - 0.00081 19.2 16.9 11 6.4 0.1 8.6 8 0 0 8 8 8 2 HEAT repeat V-ATPase_H_C PF11698.3 GAM22933.1 - 0.00085 19.2 3.8 0.013 15.4 0.1 4.8 3 1 1 4 4 4 1 V-ATPase subunit H Hexokinase_2 PF03727.11 GAM22933.1 - 0.0036 16.5 1.0 0.0083 15.3 0.2 2.1 2 0 0 2 2 2 1 Hexokinase HEAT_EZ PF13513.1 GAM22933.1 - 0.48 10.9 2.7 1.5e+02 3.0 0.1 5.4 4 1 1 5 5 5 0 HEAT-like repeat ATG16 PF08614.6 GAM22934.1 - 0.00055 19.8 14.1 0.00055 19.8 9.8 7.9 4 1 2 7 7 7 4 Autophagy protein 16 (ATG16) Fez1 PF06818.10 GAM22934.1 - 0.0019 18.2 21.7 0.0019 18.2 15.1 5.4 3 1 1 5 5 5 1 Fez1 IncA PF04156.9 GAM22934.1 - 0.0059 16.2 21.6 0.0059 16.2 15.0 6.9 3 1 2 5 5 5 2 IncA protein NDT80_PhoG PF05224.7 GAM22935.1 - 0.059 13.3 13.8 0.069 13.1 9.6 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family SNF2_N PF00176.18 GAM22936.1 - 3.4e-27 95.0 0.1 6.4e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM22936.1 - 6.1e-10 38.8 0.0 1.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 GAM22936.1 - 0.0048 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DDDD PF10161.4 GAM22936.1 - 0.68 9.6 6.2 2.7 7.6 4.3 2.1 1 0 0 1 1 1 0 Putative mitochondrial precursor protein FNIP PF05725.7 GAM22937.1 - 9.1e-19 67.1 3.9 2.9e-08 33.5 0.0 6.2 4 2 1 6 6 6 4 FNIP Repeat Arf PF00025.16 GAM22938.1 - 6.8e-42 142.6 0.0 8.5e-30 103.2 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 GAM22938.1 - 6e-08 33.2 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM22938.1 - 0.002 17.5 0.1 0.0039 16.5 0.1 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM22938.1 - 0.0037 16.5 0.7 0.013 14.7 0.0 2.2 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit AAA PF00004.24 GAM22938.1 - 0.01 16.0 0.0 0.06 13.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 GAM22938.1 - 0.015 15.2 0.7 0.052 13.4 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM22938.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAM22938.1 - 0.037 14.1 0.4 0.27 11.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAM22938.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM22938.1 - 0.067 12.8 0.1 2.1 7.9 0.1 2.3 1 1 0 1 1 1 0 NACHT domain SRP54 PF00448.17 GAM22938.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Dicty_REP PF05086.7 GAM22938.1 - 1.4 6.5 10.7 2.1 5.9 7.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ashwin PF15323.1 GAM22938.1 - 4 7.3 13.3 7.4 6.4 9.2 1.4 1 0 0 1 1 1 0 Developmental protein Rad60-SLD_2 PF13881.1 GAM22939.1 - 3.1e-05 23.8 0.3 0.00013 21.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Med15 PF09606.5 GAM22939.1 - 0.023 12.9 21.8 0.007 14.6 4.8 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CagX PF03524.10 GAM22939.1 - 0.053 12.7 7.9 0.48 9.6 1.6 2.7 3 0 0 3 3 3 0 Conjugal transfer protein Cation_efflux PF01545.16 GAM22939.1 - 0.11 11.5 0.5 1.7 7.6 1.1 2.1 1 1 1 2 2 2 0 Cation efflux family FimP PF09766.4 GAM22939.1 - 0.41 9.6 13.4 0.21 10.5 1.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein Ctr PF04145.10 GAM22939.1 - 0.41 10.6 8.0 3.5 7.6 0.1 2.8 2 1 1 3 3 3 0 Ctr copper transporter family RAB3GAP2_N PF14655.1 GAM22939.1 - 0.64 8.9 8.3 2.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4131 PF13567.1 GAM22939.1 - 1.4 8.2 12.4 1.2 8.5 2.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Zip PF02535.17 GAM22939.1 - 1.5 7.7 4.5 2.8 6.8 3.1 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter CDK2AP PF09806.4 GAM22939.1 - 2.9 8.0 11.2 2.9 8.0 2.2 2.5 2 1 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein APC_CDC26 PF10471.4 GAM22939.1 - 6.1 7.6 23.6 3 8.6 3.3 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 FAM176 PF14851.1 GAM22939.1 - 6.7 6.3 6.3 12 5.5 0.8 2.5 2 0 0 2 2 2 0 FAM176 family Ribonuclease_T2 PF00445.13 GAM22940.1 - 5e-49 166.5 0.1 5.7e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family WD40 PF00400.27 GAM22942.1 - 4.5e-48 159.4 26.9 1.2e-09 37.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM22942.1 - 0.00084 19.0 0.0 0.81 9.3 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Adap_comp_sub PF00928.16 GAM22943.1 - 5e-92 307.7 0.1 6.6e-92 307.3 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM22943.1 - 5.5e-10 39.1 1.3 9.6e-10 38.3 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 GAM22943.1 - 0.0052 16.3 0.1 0.012 15.1 0.1 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain BLYB PF05289.6 GAM22943.1 - 0.051 13.3 0.3 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Sec1 PF00995.18 GAM22944.1 - 2.9e-12 46.0 0.2 1.8e-10 40.1 0.1 2.5 2 1 0 2 2 2 2 Sec1 family Ribosomal_S3Ae PF01015.13 GAM22945.1 - 5.2e-75 251.0 6.5 6.6e-75 250.7 4.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 GAM22945.1 - 0.017 14.4 0.0 0.071 12.4 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region GatB_Yqey PF02637.13 GAM22945.1 - 0.034 13.8 0.6 0.057 13.1 0.4 1.4 1 0 0 1 1 1 0 GatB domain Ank_2 PF12796.2 GAM22946.1 - 5.9e-31 106.6 1.9 1.1e-17 64.1 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM22946.1 - 1.5e-28 97.1 8.8 2.4e-07 30.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 GAM22946.1 - 1.2e-21 76.6 4.5 6.5e-07 29.6 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM22946.1 - 2.2e-16 59.4 5.9 1.2e-07 31.7 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM22946.1 - 4e-16 57.5 2.0 0.00047 20.1 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat SopE_GEF PF07487.8 GAM22946.1 - 0.011 15.6 0.1 0.051 13.5 0.0 2.0 2 0 0 2 2 2 0 SopE GEF domain CBM49 PF09478.5 GAM22947.1 - 1.5e-16 60.2 1.5 3.2e-16 59.1 0.7 1.8 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 TRAP_beta PF05753.9 GAM22947.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Ndc1_Nup PF09531.5 GAM22948.1 - 0.73 8.1 4.5 0.88 7.9 3.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NST1 PF13945.1 GAM22948.1 - 0.9 9.5 9.6 1.3 9.0 6.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator GST_C PF00043.20 GAM22950.1 - 1.9e-08 34.1 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM22950.1 - 4.3e-05 23.9 0.0 5.6e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM22950.1 - 0.0029 17.4 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fe_dep_repr_C PF02742.10 GAM22950.1 - 0.14 11.8 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain CPSF73-100_C PF11718.3 GAM22951.1 - 3.9e-46 157.1 6.0 1.1e-45 155.6 4.2 1.8 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 GAM22951.1 - 5.8e-30 103.8 0.0 1.9e-29 102.1 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 GAM22951.1 - 3.6e-17 62.6 0.0 8.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM22951.1 - 1.3e-13 50.9 0.2 2e-12 47.0 0.1 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 GAM22951.1 - 1.3e-08 34.4 0.1 2.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 GAM22951.1 - 9.3e-07 28.6 0.0 4.3e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cyclin PF08613.6 GAM22952.1 - 1.4e-07 31.9 1.5 1.4e-07 31.9 1.0 3.3 3 2 0 3 3 3 1 Cyclin PP2C_2 PF13672.1 GAM22953.1 - 8.1e-05 22.1 0.9 0.085 12.2 0.0 3.5 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.7 GAM22953.1 - 0.062 12.9 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CBS PF00571.23 GAM22954.1 - 9.8e-31 105.2 2.8 2.1e-11 43.4 0.0 4.1 4 0 0 4 4 4 3 CBS domain LAP2alpha PF11560.3 GAM22954.1 - 0.13 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha CsgG PF03783.9 GAM22955.1 - 0.025 13.6 0.4 0.053 12.6 0.1 1.7 2 1 0 2 2 2 0 Curli production assembly/transport component CsgG PH_8 PF15409.1 GAM22955.1 - 0.028 14.4 0.3 0.079 13.0 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Citrate_synt PF00285.16 GAM22956.1 - 3.1e-22 78.8 0.0 1.6e-18 66.5 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 GAM22956.1 - 5.3e-09 35.8 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAM22956.1 - 0.0022 17.6 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain FNIP PF05725.7 GAM22957.1 - 3.5e-63 209.3 16.2 1.4e-11 44.1 1.4 8.6 6 2 1 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM22957.1 - 0.1 12.5 9.2 6.6 6.7 0.0 5.8 3 2 3 6 6 6 0 Protein of unknown function (DUF1769) Telomerase_RBD PF12009.3 GAM22957.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Acetyltransf_1 PF00583.19 GAM22958.1 - 2.5e-15 56.2 0.0 3.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM22958.1 - 4e-09 36.5 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM22958.1 - 1e-08 34.7 0.1 1.9e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 GAM22958.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM22958.1 - 1.8e-05 24.6 0.0 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM22958.1 - 0.00062 19.6 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM22958.1 - 0.0018 18.4 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM22958.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SRP9-21 PF05486.7 GAM22958.1 - 0.034 13.8 0.4 0.071 12.8 0.3 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Acetyltransf_CG PF14542.1 GAM22958.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SSP160 PF06933.6 GAM22958.1 - 0.34 8.8 4.7 0.38 8.6 3.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Erf4 PF10256.4 GAM22959.1 - 0.0027 17.5 0.3 0.0055 16.5 0.2 1.6 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family UPF0093 PF03653.8 GAM22959.1 - 0.059 13.3 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) AAA PF00004.24 GAM22960.1 - 2e-99 328.9 0.0 3.7e-49 166.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 GAM22960.1 - 1.8e-21 75.8 0.3 6.2e-21 74.1 0.2 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 GAM22960.1 - 1.3e-14 53.8 0.0 3.6e-06 26.2 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM22960.1 - 9.2e-14 51.7 0.2 8.5e-06 25.9 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAM22960.1 - 2e-13 50.6 0.0 6.8e-07 29.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM22960.1 - 3.1e-13 50.0 0.1 4.3e-05 23.5 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 GAM22960.1 - 4e-12 47.0 0.0 8.5e-05 23.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 GAM22960.1 - 4.4e-12 46.0 0.0 1.3e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM22960.1 - 9.6e-12 44.8 0.2 4e-06 26.6 0.0 3.5 4 2 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAM22960.1 - 3.9e-11 42.9 0.0 2.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 GAM22960.1 - 1.3e-09 37.5 0.0 0.00085 18.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin CDC48_2 PF02933.12 GAM22960.1 - 5.2e-09 35.6 0.0 1.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Arch_ATPase PF01637.13 GAM22960.1 - 1.9e-08 34.3 0.1 0.22 11.1 0.0 3.8 2 2 1 3 3 3 3 Archaeal ATPase AAA_25 PF13481.1 GAM22960.1 - 2.3e-08 33.6 2.6 0.33 10.3 0.0 4.2 2 2 1 4 4 4 3 AAA domain TIP49 PF06068.8 GAM22960.1 - 2.5e-08 33.0 0.0 0.0019 17.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 GAM22960.1 - 7e-08 32.0 0.0 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 GAM22960.1 - 9.4e-08 32.1 0.0 0.0065 16.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 GAM22960.1 - 1e-07 31.3 0.5 0.0089 15.2 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 GAM22960.1 - 2.4e-07 30.5 0.2 1.7e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 GAM22960.1 - 2.6e-07 30.9 0.0 0.025 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 GAM22960.1 - 3.2e-07 30.1 0.1 0.14 11.7 0.0 4.1 3 1 0 4 4 4 2 NACHT domain AAA_28 PF13521.1 GAM22960.1 - 5.1e-07 29.7 0.0 0.04 13.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 GAM22960.1 - 1.2e-06 28.1 0.0 0.0015 18.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 GAM22960.1 - 1.6e-06 28.4 0.0 0.012 15.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Sigma54_activ_2 PF14532.1 GAM22960.1 - 1.8e-06 28.0 0.0 0.028 14.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 GAM22960.1 - 4.3e-06 26.5 0.0 0.032 13.8 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein Parvo_NS1 PF01057.12 GAM22960.1 - 4.6e-06 25.7 0.1 0.025 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 GAM22960.1 - 7.1e-06 25.6 0.9 0.093 12.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain NB-ARC PF00931.17 GAM22960.1 - 1.4e-05 24.1 0.0 0.099 11.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 GAM22960.1 - 2.3e-05 23.9 0.0 0.21 11.0 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 GAM22960.1 - 2.6e-05 23.4 0.4 2.4 7.2 0.0 3.4 2 1 1 3 3 3 1 KaiC ResIII PF04851.10 GAM22960.1 - 3.6e-05 23.6 0.0 0.0088 15.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 GAM22960.1 - 5.9e-05 22.7 0.0 0.32 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 GAM22960.1 - 0.00012 21.0 0.0 0.1 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.6 GAM22960.1 - 0.00028 20.4 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 GAM22960.1 - 0.00059 19.7 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.10 GAM22960.1 - 0.00093 18.9 0.2 1.4 8.5 0.0 3.5 3 0 0 3 3 3 1 NTPase SKI PF01202.17 GAM22960.1 - 0.00093 19.0 0.2 1.8 8.3 0.0 2.9 3 0 0 3 3 2 1 Shikimate kinase ATP-synt_ab PF00006.20 GAM22960.1 - 0.0014 18.1 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 GAM22960.1 - 0.0015 18.8 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 GAM22960.1 - 0.002 17.4 0.1 0.89 8.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Rad17 PF03215.10 GAM22960.1 - 0.0022 16.7 0.0 1.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 GAM22960.1 - 0.0059 16.0 0.4 2.4 7.4 0.0 3.6 4 0 0 4 4 4 1 AAA-like domain UPF0079 PF02367.12 GAM22960.1 - 0.007 15.9 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 GAM22960.1 - 0.02 14.3 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 GAM22960.1 - 0.022 13.7 0.0 2.1 7.2 0.0 3.0 2 2 1 3 3 3 0 KAP family P-loop domain DUF2075 PF09848.4 GAM22960.1 - 0.026 13.4 0.0 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 GAM22960.1 - 0.049 13.1 0.0 9 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 GAM22960.1 - 0.07 11.9 0.0 6 5.5 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_30 PF13604.1 GAM22960.1 - 0.13 11.8 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 GAM22960.1 - 0.15 11.2 0.1 14 4.7 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 DAP3 PF10236.4 GAM22960.1 - 0.15 10.9 0.0 15 4.3 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Hid1 PF12722.2 GAM22961.1 - 4.2e-104 349.0 31.9 9.5e-94 314.7 12.3 2.7 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 GAM22961.1 - 1.6e-77 261.2 8.7 7.2e-77 259.0 6.0 1.9 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein API5 PF05918.6 GAM22961.1 - 3.8 5.8 5.4 2.4 6.5 1.0 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) FNIP PF05725.7 GAM22962.1 - 1.1e-54 182.1 15.9 7.3e-12 45.0 0.1 9.5 8 2 3 11 11 11 8 FNIP Repeat FNIP PF05725.7 GAM22963.1 - 2.5e-62 206.6 19.2 1e-11 44.5 0.0 8.9 4 3 2 9 9 9 9 FNIP Repeat Coiled PF05710.7 GAM22964.1 - 3.6e-05 24.1 10.3 4e-05 23.9 7.2 1.1 1 0 0 1 1 1 1 Coiled coil Binary_toxB PF03495.9 GAM22964.1 - 0.05 12.2 1.6 0.055 12.0 1.1 1.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA UbiA PF01040.13 GAM22965.1 - 3.2e-26 92.1 10.8 3.2e-26 92.1 7.5 1.7 1 1 0 2 2 2 1 UbiA prenyltransferase family Syja_N PF02383.13 GAM22965.1 - 0.0036 16.1 0.8 0.0062 15.3 0.5 1.3 1 0 0 1 1 1 1 SacI homology domain DUF443 PF04276.7 GAM22965.1 - 0.21 10.9 2.1 0.33 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF443) Exo5 PF09810.4 GAM22965.1 - 0.22 10.6 3.2 0.3 10.2 2.2 1.2 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease PP2C PF00481.16 GAM22966.1 - 4.5e-68 229.4 0.2 4.5e-68 229.4 0.1 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C G-alpha PF00503.15 GAM22966.1 - 6.8e-37 127.0 0.0 6.8e-37 127.0 0.0 2.7 2 1 0 2 2 2 1 G-protein alpha subunit CAF-1_p150 PF11600.3 GAM22966.1 - 0.00017 21.0 36.7 0.00031 20.1 25.4 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 GAM22966.1 - 0.14 11.4 22.9 0.27 10.5 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_UL6 PF01763.11 GAM22966.1 - 1.9 6.5 10.9 2.9 5.9 7.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CDC27 PF09507.5 GAM22966.1 - 4.7 6.3 33.4 7 5.7 23.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDRGK PF09756.4 GAM22966.1 - 7.2 5.9 34.6 13 5.1 24.0 1.3 1 0 0 1 1 1 0 DDRGK domain Pkinase PF00069.20 GAM22967.1 - 6.9e-65 218.7 0.0 5.7e-45 153.5 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22967.1 - 1.5e-27 96.2 0.0 2.9e-22 78.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM22967.1 - 6.5e-07 28.6 0.0 2.4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM22967.1 - 0.00023 20.9 0.1 0.002 17.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM22967.1 - 0.0011 17.8 0.0 0.003 16.4 0.0 1.7 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 GAM22967.1 - 0.035 13.1 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transketolase_C PF02780.15 GAM22968.1 - 1.9e-41 140.8 0.1 3.5e-41 140.0 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 GAM22968.1 - 4.6e-40 136.9 0.0 6.7e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TRAPPC-Trs85 PF12739.2 GAM22969.1 - 4.5e-58 196.8 6.4 9.5e-57 192.5 3.1 2.7 2 1 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_8 PF13181.1 GAM22969.1 - 0.011 15.4 0.6 0.054 13.2 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM22969.1 - 0.017 15.0 0.5 0.037 13.9 0.4 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM22969.1 - 0.037 13.6 4.9 0.051 13.2 0.8 2.6 2 0 0 2 2 2 0 TPR repeat RPN7 PF10602.4 GAM22969.1 - 0.46 9.8 5.2 0.32 10.3 0.4 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_2 PF07719.12 GAM22969.1 - 0.49 10.4 6.3 0.098 12.6 0.5 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FNIP PF05725.7 GAM22970.1 - 8.6e-78 256.0 38.7 7.7e-15 54.5 0.2 11.7 9 3 2 11 11 11 10 FNIP Repeat Ribosomal_S17e PF00833.13 GAM22970.1 - 4.4e-54 181.4 1.1 7.6e-54 180.6 0.8 1.3 1 0 0 1 1 1 1 Ribosomal S17 DUF1769 PF08588.5 GAM22970.1 - 7e-06 25.9 8.6 9 6.3 0.0 6.9 4 3 2 6 6 6 2 Protein of unknown function (DUF1769) LRR_8 PF13855.1 GAM22970.1 - 0.037 13.7 7.6 33 4.3 0.1 5.6 5 1 1 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 GAM22970.1 - 0.087 12.4 13.1 13 5.5 3.8 6.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 GAM22970.1 - 0.14 12.4 3.7 34 5.2 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 GAM22970.1 - 5.3 7.4 12.9 0.86 9.8 0.7 5.5 5 2 0 5 5 5 0 Leucine Rich Repeat Cytochrome-c551 PF10643.4 GAM22971.1 - 0.15 11.3 0.1 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 MFS_1 PF07690.11 GAM22972.1 - 1.8e-18 66.4 37.0 1.8e-18 66.4 25.6 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM22972.1 - 7.1e-10 37.8 31.5 7.1e-10 37.8 21.9 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein Pkinase PF00069.20 GAM22973.1 - 2.4e-76 256.3 0.0 3.4e-76 255.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM22973.1 - 2.9e-37 128.1 0.0 4.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAM22973.1 - 4.2e-07 30.3 0.2 4.2e-07 30.3 0.2 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM22973.1 - 3.2e-05 23.0 0.0 0.00086 18.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM22973.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 GAM22973.1 - 0.043 12.8 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 GAM22973.1 - 0.093 12.1 19.8 0.13 11.6 13.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF1777 PF08648.7 GAM22973.1 - 4.2 7.0 9.0 0.4 10.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) TFIIA PF03153.8 GAM22973.1 - 5.3 6.8 20.3 7.4 6.3 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF706 PF05153.10 GAM22974.1 - 2.7e-119 397.1 6.7 3.2e-119 396.8 4.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) DUF3864 PF12980.2 GAM22974.1 - 0.0044 17.1 0.2 0.018 15.2 0.1 2.1 2 0 0 2 2 2 1 Domain of Unknown Function with PDB structure (DUF3864) HD PF01966.17 GAM22974.1 - 0.073 13.0 0.0 0.32 11.0 0.0 2.0 3 0 0 3 3 3 0 HD domain WD40 PF00400.27 GAM22975.1 - 2.6e-70 229.9 21.1 1.6e-11 43.6 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 GAM22975.1 - 3.7e-11 43.0 0.7 8.8e-05 22.2 0.1 3.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 GAM22975.1 - 6e-10 38.5 1.2 1.2e-09 37.5 0.8 1.5 1 0 0 1 1 1 1 LisH DUF1777 PF08648.7 GAM22975.1 - 0.0023 17.6 20.8 0.0036 17.0 14.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Nup160 PF11715.3 GAM22975.1 - 0.023 12.8 3.8 0.024 12.8 0.1 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.1 GAM22975.1 - 0.029 13.4 0.0 0.066 12.2 0.0 1.8 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ycf1 PF05758.7 GAM22975.1 - 0.078 10.6 10.5 0.1 10.2 7.3 1.1 1 0 0 1 1 1 0 Ycf1 Apc4_WD40 PF12894.2 GAM22975.1 - 0.092 12.2 0.1 5.4 6.5 0.0 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MIP-T3 PF10243.4 GAM22975.1 - 0.31 9.4 28.4 0.44 8.9 19.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 GAM22975.1 - 0.35 10.1 22.2 0.57 9.5 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 GAM22975.1 - 2.1 6.7 16.3 3.1 6.2 11.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.11 GAM22975.1 - 6.6 6.0 18.2 11 5.4 12.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Vfa1 PF08432.5 GAM22975.1 - 7.4 6.5 23.8 15 5.5 16.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Serglycin PF04360.7 GAM22977.1 - 0.00097 18.8 3.4 0.0034 17.1 0.1 3.1 3 0 0 3 3 3 1 Serglycin DUF2946 PF11162.3 GAM22977.1 - 1.4 9.1 18.2 0.16 12.2 2.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) COQ9 PF08511.6 GAM22978.1 - 8.5e-30 102.0 0.7 1.7e-29 101.1 0.5 1.5 1 0 0 1 1 1 1 COQ9 HeLo PF14479.1 GAM22978.1 - 0.098 12.3 0.4 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 Prion-inhibition and propagation Period_C PF12114.3 GAM22978.1 - 2.3 7.7 14.6 3.8 7.0 10.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Apt1 PF10351.4 GAM22978.1 - 10 4.8 10.6 3.1 6.5 4.8 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain KOG2701 PF09762.4 GAM22979.1 - 4e-64 216.0 0.0 4e-64 216.0 0.0 3.0 3 0 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) Ribosomal_L30 PF00327.15 GAM22980.1 - 3.2e-13 49.0 0.5 4.7e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e VHS PF00790.14 GAM22981.1 - 1.3e-23 83.2 0.0 2.7e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 GAM22981.1 - 1.8e-09 37.4 1.5 1.8e-09 37.4 1.0 2.4 2 0 0 2 2 2 1 GAT domain RabGAP-TBC PF00566.13 GAM22982.1 - 5.6e-31 107.6 2.6 1e-30 106.8 1.8 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vasculin PF15337.1 GAM22982.1 - 0.094 13.1 1.2 0.16 12.4 0.8 1.3 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 RabGAP-TBC PF00566.13 GAM22983.1 - 1.1e-11 44.6 0.2 1.1e-11 44.6 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Tir_receptor_C PF07489.6 GAM22983.1 - 1.9 8.2 5.6 2.7 7.7 3.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dicty_REP PF05086.7 GAM22983.1 - 9.9 3.7 14.2 13 3.3 9.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BCL_N PF04714.8 GAM22984.1 - 0.00011 21.6 0.7 0.00025 20.5 0.5 1.6 1 0 0 1 1 1 1 BCL7, N-terminal conserver region DUF2638 PF10937.3 GAM22984.1 - 0.019 15.9 2.0 0.46 11.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2638) PSCyt3 PF07627.6 GAM22984.1 - 0.072 12.9 0.5 0.18 11.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) CobT PF06213.7 GAM22984.1 - 0.11 11.6 0.0 0.11 11.6 0.0 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF3439 PF11921.3 GAM22984.1 - 0.43 10.3 6.4 0.3 10.8 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SAC3_GANP PF03399.11 GAM22985.1 - 4.6e-59 199.4 1.2 1.2e-58 198.0 0.8 1.8 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TIG PF01833.19 GAM22986.1 - 1.8e-64 213.7 181.5 4.4e-09 36.2 1.8 17.7 13 4 5 18 18 18 14 IPT/TIG domain EGF_2 PF07974.8 GAM22986.1 - 0.045 13.9 13.8 0.049 13.8 8.1 2.2 2 0 0 2 2 2 0 EGF-like domain EGF PF00008.22 GAM22986.1 - 6.8 6.7 10.6 6.2 6.9 5.5 2.3 2 0 0 2 2 2 0 EGF-like domain zf-DHHC PF01529.15 GAM22987.1 - 1.5e-39 135.1 11.0 1.5e-39 135.1 7.6 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Pho86 PF11124.3 GAM22987.1 - 1.4 7.8 5.4 0.18 10.7 0.6 1.8 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Pex24p PF06398.6 GAM22987.1 - 2.8 6.6 5.8 4.2 6.0 0.1 2.4 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Spt4 PF06093.8 GAM22987.1 - 6.7 6.6 7.9 14 5.6 5.5 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger PSI PF01437.20 GAM22987.1 - 7.4 6.8 12.9 4.9 7.3 6.4 2.2 1 1 1 2 2 2 0 Plexin repeat Mucin PF01456.12 GAM22988.1 - 2.2 8.0 6.8 2.3 8.0 4.7 1.0 1 0 0 1 1 1 0 Mucin-like glycoprotein CBS PF00571.23 GAM22989.1 - 1.6e-31 107.8 1.1 4.1e-14 52.0 0.0 4.2 4 0 0 4 4 4 4 CBS domain RGS PF00615.14 GAM22990.1 - 7.6e-44 148.6 14.9 2.1e-16 60.1 0.1 5.0 5 1 0 5 5 5 3 Regulator of G protein signaling domain RGS-like PF09128.6 GAM22990.1 - 3.7e-07 29.8 9.3 0.008 15.6 0.0 4.2 4 0 0 4 4 4 2 Regulator of G protein signalling-like domain CH PF00307.26 GAM22991.1 - 7.1e-43 145.0 15.4 3.5e-15 55.9 0.2 6.6 6 0 0 6 6 6 5 Calponin homology (CH) domain PH PF00169.24 GAM22991.1 - 1.3e-11 44.6 0.5 4.7e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM22991.1 - 6.8e-05 23.0 2.7 0.00051 20.2 0.1 3.8 3 0 0 3 3 3 1 Pleckstrin homology domain CAMSAP_CH PF11971.3 GAM22991.1 - 0.0028 17.2 0.0 0.37 10.4 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain FERM_N PF09379.5 GAM22991.1 - 0.0029 17.6 2.8 0.047 13.7 0.0 3.3 3 0 0 3 3 3 1 FERM N-terminal domain SecY PF00344.15 GAM22992.1 - 5.3e-98 328.1 15.8 7e-98 327.7 11.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 GAM22992.1 - 2e-18 65.6 1.9 2.3e-18 65.3 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p Usp PF00582.21 GAM22993.1 - 1.6e-05 25.1 0.1 6.4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family GARS_C PF02843.11 GAM22993.1 - 0.027 14.6 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain DUF733 PF05306.6 GAM22993.1 - 0.051 13.8 0.2 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF733) MRL1 PF13003.2 GAM22993.1 - 7 6.4 9.4 12 5.7 0.4 2.3 1 1 1 2 2 2 0 Ribosomal protein L1 CBS PF00571.23 GAM22994.1 - 5.4e-19 67.7 5.6 2.7e-06 27.0 0.0 3.4 3 0 0 3 3 3 3 CBS domain G-alpha PF00503.15 GAM22995.1 - 2.5e-122 408.3 5.2 3e-122 408.0 3.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM22995.1 - 5.6e-14 51.7 0.4 6e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM22995.1 - 0.00043 19.5 2.4 0.086 11.9 0.3 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM22995.1 - 0.012 16.1 0.9 3.3 8.2 0.0 3.1 2 2 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 GAM22995.1 - 0.065 12.6 0.1 1.6 8.1 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Malic_M PF03949.10 GAM22995.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Cullin_binding PF03556.10 GAM22996.1 - 5.2e-30 103.9 0.4 7.4e-30 103.4 0.3 1.2 1 0 0 1 1 1 1 Cullin binding FNIP PF05725.7 GAM22997.1 - 4.9e-79 260.0 27.5 9.4e-12 44.6 0.0 12.3 7 1 6 14 14 14 13 FNIP Repeat DUF3552 PF12072.3 GAM22997.1 - 0.012 14.8 29.7 0.093 11.9 8.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF1769 PF08588.5 GAM22997.1 - 0.3 11.0 2.8 2.3 8.2 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1769) Spc7 PF08317.6 GAM22997.1 - 1 7.9 15.6 2.2 6.8 10.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DDE_Tnp_4 PF13359.1 GAM22998.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM22998.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain FNIP PF05725.7 GAM22999.1 - 5.6e-71 234.2 39.8 2.1e-13 49.9 0.4 10.5 5 3 7 13 13 13 13 FNIP Repeat DUF1741 PF08427.5 GAM23000.1 - 2e-62 210.7 3.0 2e-62 210.7 2.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) JHBP PF06585.6 GAM23001.1 - 0.13 11.0 0.3 0.15 10.8 0.2 1.0 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Aldo_ket_red PF00248.16 GAM23002.1 - 1.7e-52 178.0 0.0 2e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EGF_2 PF07974.8 GAM23003.1 - 0.00044 20.3 12.2 0.00093 19.3 8.4 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.22 GAM23003.1 - 0.0006 19.7 10.9 0.0006 19.7 7.5 2.1 2 0 0 2 2 2 1 EGF-like domain EGF_CA PF07645.10 GAM23003.1 - 0.81 9.7 8.7 0.8 9.7 4.4 2.1 2 0 0 2 2 2 0 Calcium-binding EGF domain hEGF PF12661.2 GAM23003.1 - 4.8 7.4 12.6 0.059 13.4 3.3 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF Ribosomal_S13 PF00416.17 GAM23004.1 - 5.2e-38 129.7 3.6 6.2e-38 129.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAM23004.1 - 0.024 13.1 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SOG2 PF10428.4 GAM23004.1 - 0.091 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Choline_transpo PF04515.7 GAM23005.1 - 1.2e-66 224.8 37.8 1.2e-66 224.8 26.2 2.6 2 2 0 2 2 2 1 Plasma-membrane choline transporter Myosin_TH1 PF06017.8 GAM23007.1 - 0.012 14.9 2.0 0.019 14.2 1.0 1.6 2 0 0 2 2 2 0 Myosin tail RasGEF PF00617.14 GAM23008.1 - 4.9e-57 192.7 1.9 1.3e-56 191.2 1.3 1.8 1 0 0 1 1 1 1 RasGEF domain LRR_4 PF12799.2 GAM23008.1 - 8e-38 127.4 22.7 3.8e-07 29.5 0.1 8.5 3 1 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM23008.1 - 3.6e-29 100.2 28.1 3.7e-10 39.4 0.6 6.3 2 1 3 6 6 6 6 Leucine rich repeat RasGEF_N PF00618.15 GAM23008.1 - 2.5e-18 66.0 0.8 1.1e-16 60.7 0.1 3.2 2 0 0 2 2 2 1 RasGEF N-terminal motif LRR_1 PF00560.28 GAM23008.1 - 2.6e-16 57.1 19.3 0.66 10.2 0.0 13.2 13 0 0 13 13 13 4 Leucine Rich Repeat Drf_GBD PF06371.8 GAM23008.1 - 4.4e-14 52.2 0.1 1.6e-13 50.4 0.1 2.0 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAM23008.1 - 6.9e-08 32.1 0.1 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain FERM_N PF09379.5 GAM23008.1 - 4.9e-06 26.5 0.0 0.47 10.5 0.0 3.8 3 0 0 3 3 3 2 FERM N-terminal domain LRR_7 PF13504.1 GAM23008.1 - 9e-05 22.0 27.1 6.4 7.4 0.0 12.4 14 0 0 14 14 14 1 Leucine rich repeat LRR_6 PF13516.1 GAM23008.1 - 0.084 12.9 9.3 62 4.1 0.1 7.6 8 0 0 8 8 8 0 Leucine Rich repeat dCMP_cyt_deam_1 PF00383.17 GAM23009.1 - 1.4e-22 79.2 1.6 2.1e-22 78.6 1.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAM23009.1 - 0.59 9.9 10.4 0.19 11.5 3.1 2.7 2 1 0 2 2 2 0 Bd3614-like deaminase Hemerythrin PF01814.18 GAM23010.1 - 3.2e-13 50.0 1.3 6.7e-13 48.9 1.0 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2408 PF10303.4 GAM23010.1 - 0.0041 17.2 2.5 0.095 12.8 0.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) DUF1186 PF06685.6 GAM23010.1 - 0.0092 15.1 0.5 0.016 14.3 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1186) TcdB_N PF12918.2 GAM23010.1 - 0.01 15.8 1.8 0.053 13.5 0.1 2.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Beach PF02138.13 GAM23010.1 - 0.034 13.5 0.8 0.049 13.0 0.5 1.3 1 1 0 1 1 1 0 Beige/BEACH domain AT_hook PF02178.14 GAM23011.1 - 9.7 6.2 48.5 0.78 9.6 3.7 4.6 4 0 0 4 4 4 0 AT hook motif Pro-kuma_activ PF09286.6 GAM23014.1 - 4.4e-27 94.8 0.4 5.2e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF1980 PF09323.5 GAM23014.1 - 0.017 14.9 0.8 0.028 14.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2140 PF09911.4 GAM23014.1 - 0.14 11.3 0.8 0.24 10.5 0.2 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3596 PF12167.3 GAM23015.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) FNIP PF05725.7 GAM23016.1 - 6.3e-32 109.2 13.3 1.2e-08 34.7 0.5 5.0 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.7 GAM23017.1 - 2.3e-44 149.0 26.3 1.3e-11 44.2 1.1 4.6 1 1 5 6 6 6 6 FNIP Repeat DUF1769 PF08588.5 GAM23017.1 - 0.00047 20.0 5.8 6.8 6.7 0.0 4.8 1 1 4 5 5 5 3 Protein of unknown function (DUF1769) SCF PF02404.10 GAM23017.1 - 0.046 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Stem cell factor Rotavirus_VP3 PF06929.6 GAM23018.1 - 0.014 13.3 0.3 0.017 13.0 0.2 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein FNIP PF05725.7 GAM23019.1 - 6.2e-30 102.8 22.6 3.1e-09 36.6 0.3 5.3 1 1 6 7 7 7 7 FNIP Repeat Ded_cyto PF06920.8 GAM23019.1 - 0.016 14.5 0.0 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Dedicator of cytokinesis DUF1769 PF08588.5 GAM23019.1 - 0.2 11.6 1.8 4.8 7.1 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1769) tRNA-synt_1 PF00133.17 GAM23020.1 - 3.2e-207 689.2 0.5 3.2e-207 689.2 0.3 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM23020.1 - 2.6e-40 137.6 0.2 2.6e-40 137.6 0.2 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM23020.1 - 4.3e-15 55.2 5.9 2.6e-07 29.6 0.0 5.2 4 1 1 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAM23020.1 - 7.1e-07 28.6 0.0 7.1e-07 28.6 0.0 3.2 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAM23020.1 - 0.2 10.7 6.4 0.29 10.2 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain PGI PF00342.14 GAM23021.1 - 3.9e-216 718.1 0.0 4.5e-216 717.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SOR_SNZ PF01680.12 GAM23022.1 - 3e-111 370.0 6.5 3e-111 370.0 4.5 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 GAM23022.1 - 9.8e-07 28.0 0.7 9.8e-07 28.0 0.5 2.8 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG IGPS PF00218.16 GAM23022.1 - 0.0015 17.6 0.8 0.11 11.4 0.0 2.9 3 1 0 3 3 3 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 GAM23022.1 - 0.0025 16.7 1.9 0.13 11.1 0.0 3.0 2 1 1 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 GAM23022.1 - 0.0042 15.9 0.1 0.43 9.3 0.0 2.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) OMPdecase PF00215.19 GAM23022.1 - 0.028 13.8 0.1 1.7 7.9 0.0 2.5 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family FMN_dh PF01070.13 GAM23022.1 - 0.03 13.1 0.7 0.44 9.3 0.0 2.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NMO PF03060.10 GAM23022.1 - 0.039 13.1 0.2 0.039 13.1 0.1 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase Lsm_C PF14894.1 GAM23022.1 - 0.72 9.3 5.2 6.7 6.3 0.0 3.8 4 0 0 4 4 4 0 Lsm C-terminal SNO PF01174.14 GAM23023.1 - 1.4e-40 138.9 0.1 1.8e-40 138.6 0.1 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 GAM23023.1 - 1.2e-07 31.4 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 GAM23023.1 - 0.0058 16.1 0.1 0.023 14.1 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 GAM23023.1 - 0.044 13.5 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 DJ-1_PfpI PF01965.19 GAM23023.1 - 0.075 12.4 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 DJ-1/PfpI family Ribosomal_L11_N PF03946.9 GAM23024.1 - 6.3e-15 54.3 0.2 1e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 GAM23024.1 - 4.3e-12 45.9 0.3 7.5e-12 45.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain DUF971 PF06155.7 GAM23025.1 - 0.097 13.1 0.1 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF971) SR-25 PF10500.4 GAM23025.1 - 0.12 11.7 1.4 0.16 11.4 0.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-UBR PF02207.15 GAM23026.1 - 5.1e-18 64.5 11.4 5.1e-18 64.5 7.9 3.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 GAM23026.1 - 1.3e-07 31.2 0.1 3.9e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PHD PF00628.24 GAM23026.1 - 1.8 8.2 16.0 0.79 9.4 0.4 3.8 3 0 0 3 3 3 0 PHD-finger Amidohydro_4 PF13147.1 GAM23027.1 - 5e-28 98.9 0.3 5.9e-28 98.6 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 GAM23027.1 - 7.4e-12 45.5 0.4 1.4e-09 38.0 0.3 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 GAM23027.1 - 2.5e-11 43.4 1.4 5.7e-07 29.0 0.0 3.1 2 1 2 4 4 4 2 Amidohydrolase family Amidohydro_5 PF13594.1 GAM23027.1 - 3.8e-11 42.6 0.3 8.5e-11 41.5 0.2 1.7 1 0 0 1 1 1 1 Amidohydrolase SHOCT PF09851.4 GAM23027.1 - 0.051 13.0 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 0 Short C-terminal domain DEAD PF00270.24 GAM23028.1 - 6.2e-21 74.6 0.0 1.9e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM23028.1 - 5.3e-17 61.4 0.0 1.4e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SOBP PF15279.1 GAM23028.1 - 0.31 11.3 7.7 0.55 10.5 5.4 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein MaoC_dehydratas PF01575.14 GAM23029.1 - 1.2e-24 85.9 0.0 1.7e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAM23029.1 - 5.2e-05 23.0 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase JAB PF01398.16 GAM23030.1 - 1.2e-20 73.3 0.0 1.2e-20 73.3 0.0 4.0 3 1 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 GAM23030.1 - 7.9e-17 61.2 1.3 7.9e-17 61.2 0.9 3.3 3 1 1 4 4 4 1 USP8 dimerisation domain Prok-JAB PF14464.1 GAM23030.1 - 5.3e-06 25.9 2.7 7.4e-06 25.4 0.0 2.6 2 1 0 2 2 2 1 Prokaryotic homologs of the JAB domain ATS3 PF06232.6 GAM23030.1 - 0.021 14.4 0.1 0.089 12.3 0.0 2.1 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) DUF2042 PF09743.4 GAM23031.1 - 9.6e-85 284.1 10.0 9.6e-85 284.1 7.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) DUF2201_N PF13203.1 GAM23031.1 - 0.013 14.7 5.1 0.026 13.7 3.5 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain FeoC PF09012.5 GAM23031.1 - 0.013 15.1 0.1 0.14 11.8 0.0 2.6 2 0 0 2 2 2 0 FeoC like transcriptional regulator zf-UBR PF02207.15 GAM23032.1 - 2.6e-11 43.0 6.7 2.6e-11 43.0 4.6 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PrmA PF06325.8 GAM23032.1 - 0.14 11.2 0.7 0.3 10.1 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2283 PF10049.4 GAM23033.1 - 0.0054 16.5 0.4 0.0084 15.9 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2283) HEAT PF02985.17 GAM23034.1 - 1.9e-45 148.8 20.7 8.7e-05 22.2 0.0 14.3 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.1 GAM23034.1 - 2.5e-34 117.4 0.2 1.7e-06 28.1 0.0 6.6 2 1 5 7 7 7 7 HEAT repeats Adaptin_N PF01602.15 GAM23034.1 - 1.8e-11 43.0 8.7 0.002 16.5 0.4 4.6 2 1 3 5 5 5 5 Adaptin N terminal region CLASP_N PF12348.3 GAM23034.1 - 2.4e-10 40.1 0.7 0.0055 16.0 0.0 4.5 2 1 2 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 GAM23034.1 - 3.4e-09 36.9 0.4 0.2 12.0 0.0 6.5 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAM23034.1 - 8.9e-08 32.3 9.9 0.41 11.2 0.0 9.0 6 3 5 11 11 11 1 HEAT-like repeat DUF2435 PF10363.4 GAM23034.1 - 0.00043 20.1 0.3 2.9 7.8 0.1 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 GAM23034.1 - 0.0006 19.5 2.4 16 5.5 0.0 6.3 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat tRNA-synt_His PF13393.1 GAM23034.1 - 0.0046 16.0 1.4 0.042 12.8 0.3 2.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase TFCD_C PF12612.3 GAM23034.1 - 0.0066 15.8 1.6 20 4.5 0.0 3.6 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal UCR_UQCRX_QCR9 PF05365.7 GAM23035.1 - 9.3e-22 76.4 0.4 1e-21 76.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Pkinase PF00069.20 GAM23036.1 - 4.9e-61 206.1 0.7 3.6e-60 203.3 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23036.1 - 1.5e-28 99.6 1.6 4.7e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 GAM23036.1 - 2.5e-06 27.9 0.4 6e-06 26.6 0.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 GAM23036.1 - 0.00052 19.8 0.1 0.05 13.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM23036.1 - 0.0048 15.8 0.2 0.029 13.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 GAM23036.1 - 0.007 15.2 0.3 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Peptidase_M4 PF01447.13 GAM23036.1 - 0.44 10.6 2.3 9.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain GRIP PF01465.15 GAM23037.1 - 5.4e-14 51.4 0.9 1.4e-13 50.0 0.6 1.8 1 0 0 1 1 1 1 GRIP domain AAA_13 PF13166.1 GAM23037.1 - 0.0014 17.1 27.8 0.0014 17.1 19.3 5.2 2 1 2 4 4 4 1 AAA domain Reo_sigmaC PF04582.7 GAM23037.1 - 0.0024 17.1 45.0 0.0055 15.9 2.8 5.8 2 1 4 6 6 6 3 Reovirus sigma C capsid protein Spc7 PF08317.6 GAM23037.1 - 0.0048 15.5 18.7 0.0048 15.5 13.0 7.3 3 1 4 7 7 7 4 Spc7 kinetochore protein ADH_zinc_N_2 PF13602.1 GAM23038.1 - 4.3e-14 53.4 0.0 9.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM23038.1 - 3.2e-09 36.5 0.0 5e-08 32.6 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 GAM23038.1 - 6.4e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 GAM23038.1 - 0.04 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM23038.1 - 0.051 13.4 0.2 0.23 11.3 0.1 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SAM_1 PF00536.25 GAM23040.1 - 0.0014 18.7 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM23040.1 - 0.0038 17.0 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4609 PF15382.1 GAM23040.1 - 0.034 13.8 0.2 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) Sigma70_ner PF04546.8 GAM23040.1 - 1.5 8.3 6.9 3.2 7.3 4.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 GAM23040.1 - 2.9 8.1 13.5 6.9 6.9 9.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 GAM23040.1 - 3.1 8.1 9.0 6.5 7.1 6.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 GAM23040.1 - 4.1 6.9 13.7 9.9 5.6 9.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin DUF3767 PF12597.3 GAM23043.1 - 4.4e-19 68.2 0.0 5.4e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Zn_Tnp_IS1595 PF12760.2 GAM23044.1 - 0.00027 20.6 22.1 0.031 14.0 3.9 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 GAM23044.1 - 0.019 14.8 13.7 0.086 12.7 0.8 2.8 3 0 0 3 3 3 0 Ribosomal L37ae protein family PhnA_Zn_Ribbon PF08274.7 GAM23044.1 - 0.19 11.5 7.7 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon OrfB_Zn_ribbon PF07282.6 GAM23044.1 - 0.53 9.9 14.5 2 8.1 1.7 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Rpr2 PF04032.11 GAM23044.1 - 0.78 9.6 11.9 0.9 9.4 3.8 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2HC5 PF06221.8 GAM23044.1 - 1.1 9.0 6.6 0.18 11.5 1.2 2.1 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-B_box PF00643.19 GAM23044.1 - 3.4 7.6 15.1 5 7.1 3.5 2.9 2 1 0 2 2 2 0 B-box zinc finger FYVE PF01363.16 GAM23044.1 - 7.8 6.4 16.4 3.2e+03 -1.9 11.3 2.9 1 1 0 1 1 1 0 FYVE zinc finger CBS PF00571.23 GAM23045.1 - 9.6e-29 98.9 0.3 1.4e-15 56.7 0.1 2.3 2 0 0 2 2 2 2 CBS domain FNIP PF05725.7 GAM23046.1 - 4.5e-14 52.1 2.6 2.2e-05 24.2 0.0 6.3 5 1 0 5 5 5 4 FNIP Repeat F-box-like PF12937.2 GAM23046.1 - 0.001 18.7 0.9 0.0024 17.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like ADP_ribosyl_GH PF03747.9 GAM23047.1 - 3.1e-37 128.9 0.0 3.8e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase PaREP1 PF05942.6 GAM23047.1 - 0.091 12.6 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family SOG2 PF10428.4 GAM23048.1 - 5.8 5.4 9.8 7 5.1 6.8 1.2 1 1 0 1 1 1 0 RAM signalling pathway protein DDE_Tnp_4 PF13359.1 GAM23049.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM23049.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain ADP_ribosyl_GH PF03747.9 GAM23050.1 - 4.8e-16 59.3 0.0 5.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Kelch_6 PF13964.1 GAM23051.1 - 1.1e-13 50.6 11.3 2.1e-06 27.6 0.0 5.3 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 GAM23051.1 - 5.3e-11 42.1 11.4 2.8e-07 30.1 0.0 6.0 6 1 1 7 7 7 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM23051.1 - 2.6e-09 36.9 4.6 0.0079 16.3 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM23051.1 - 3.1e-05 23.4 14.0 0.0026 17.2 0.0 5.0 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 GAM23051.1 - 4e-05 23.2 3.0 0.0033 17.1 0.0 3.8 4 0 0 4 4 4 1 Kelch motif zf-B_box PF00643.19 GAM23051.1 - 0.013 15.3 8.1 0.013 15.3 5.6 2.4 2 0 0 2 2 2 0 B-box zinc finger Baculo_PEP_C PF04513.7 GAM23051.1 - 0.035 13.9 0.2 0.076 12.8 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM23051.1 - 0.12 12.1 1.7 0.33 10.7 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AF0941-like PF14591.1 GAM23051.1 - 0.16 12.0 1.9 0.81 9.7 1.3 2.2 1 1 0 1 1 1 0 AF0941-like Kelch_5 PF13854.1 GAM23051.1 - 1.6 8.7 13.5 2.4 8.2 0.2 4.3 4 0 0 4 4 4 0 Kelch motif Myb_DNA-binding PF00249.26 GAM23052.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain RNA_lig_T4_1 PF09511.5 GAM23053.1 - 5.2e-44 150.3 0.0 1.1e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase PA14 PF07691.7 GAM23054.1 - 2e-14 53.4 1.7 3.6e-14 52.6 1.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM23054.1 - 0.00044 20.0 23.4 0.00083 19.1 5.1 13.0 13 1 1 14 14 14 6 Dictyostelium (slime mold) repeat Herpes_BLRF2 PF05812.7 GAM23055.1 - 0.0074 16.0 1.1 0.0074 16.0 0.7 9.5 3 2 7 10 10 10 4 Herpesvirus BLRF2 protein IncA PF04156.9 GAM23055.1 - 0.011 15.3 144.0 0.045 13.3 9.8 5.9 2 1 4 6 6 6 0 IncA protein GAS PF13851.1 GAM23055.1 - 0.012 14.8 122.2 0.099 11.8 16.9 6.0 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding Acetyltransf_1 PF00583.19 GAM23056.1 - 5e-14 52.0 0.0 7.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM23056.1 - 7.8e-11 41.9 0.2 1.2e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM23056.1 - 0.00013 21.9 0.2 0.00017 21.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM23056.1 - 0.00052 20.2 0.0 0.00071 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM23056.1 - 0.0021 18.1 0.0 0.0028 17.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Cys_rich_CPXG PF14255.1 GAM23056.1 - 0.0035 17.1 1.1 2.3 8.1 0.1 2.3 2 0 0 2 2 2 2 Cysteine-rich CPXCG Acetyltransf_9 PF13527.1 GAM23056.1 - 0.055 13.3 0.0 0.092 12.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Epimerase PF01370.16 GAM23057.1 - 7.2e-25 87.7 0.0 1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM23057.1 - 8.5e-11 41.0 0.4 5.5e-10 38.3 0.3 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM23057.1 - 4.4e-09 36.5 0.0 9e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM23057.1 - 2e-06 26.8 0.2 3.6e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAM23057.1 - 1.7e-05 23.8 0.3 9.5e-05 21.4 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 GAM23057.1 - 0.00015 21.6 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DnaB PF00772.16 GAM23057.1 - 0.002 17.9 0.1 0.039 13.8 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase N terminal domain KR PF08659.5 GAM23057.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 KR domain PX PF00787.19 GAM23058.1 - 2.9e-19 68.9 0.9 3.9e-19 68.5 0.6 1.2 1 0 0 1 1 1 1 PX domain PQ-loop PF04193.9 GAM23059.1 - 5.9e-09 35.3 21.6 0.00017 21.0 4.4 2.6 2 0 0 2 2 2 2 PQ loop repeat Zip PF02535.17 GAM23059.1 - 0.0099 14.9 6.6 1.2 8.1 0.0 2.7 2 1 0 2 2 2 1 ZIP Zinc transporter DUF1191 PF06697.7 GAM23059.1 - 0.018 13.8 0.0 0.096 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DUF1183 PF06682.7 GAM23059.1 - 0.27 10.8 8.4 0.18 11.3 3.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1183) Neur_chan_memb PF02932.11 GAM23059.1 - 1.1 9.1 9.9 1.1 9.1 2.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PGA2 PF07543.7 GAM23059.1 - 6.6 6.5 20.3 6.7 6.5 1.1 2.7 2 1 0 2 2 2 0 Protein trafficking PGA2 Methyltransf_31 PF13847.1 GAM23060.1 - 7.3e-18 64.5 0.0 8.7e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM23060.1 - 3.4e-15 56.1 0.0 4.1e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23060.1 - 1.8e-14 54.0 0.0 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23060.1 - 1.1e-12 48.3 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23060.1 - 3.4e-12 46.9 0.0 4.7e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23060.1 - 3.4e-08 32.8 0.0 4.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM23060.1 - 4.7e-08 33.3 0.0 6.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM23060.1 - 2.8e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM23060.1 - 1.1e-05 24.8 0.0 2e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_21 PF05050.7 GAM23060.1 - 0.017 15.0 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain MetW PF07021.7 GAM23060.1 - 0.08 12.3 0.0 0.24 10.7 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.12 GAM23060.1 - 0.085 11.8 0.0 0.24 10.3 0.0 1.6 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Gelsolin PF00626.17 GAM23062.1 - 8e-34 115.1 0.0 9.4e-11 41.2 0.1 4.1 4 0 0 4 4 4 3 Gelsolin repeat VHP PF02209.14 GAM23062.1 - 6e-12 45.0 2.0 1.3e-11 44.0 1.4 1.6 1 0 0 1 1 1 1 Villin headpiece domain PEPCK PF00821.13 GAM23063.1 - 9.6e-286 948.6 0.0 1.1e-285 948.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase TPR_11 PF13414.1 GAM23064.1 - 1.8e-19 69.1 15.6 2.6e-07 30.1 0.0 6.6 5 2 1 6 6 6 5 TPR repeat TPR_2 PF07719.12 GAM23064.1 - 1.2e-12 46.7 15.2 0.19 11.7 0.0 9.8 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM23064.1 - 1.8e-11 43.8 13.6 0.038 13.9 0.1 7.7 4 2 6 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM23064.1 - 1.5e-10 40.7 9.2 7.2 7.5 0.0 9.6 5 1 6 11 11 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM23064.1 - 1.8e-10 39.9 11.3 0.007 15.9 0.1 8.4 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM23064.1 - 2.6e-10 40.5 18.7 0.018 15.3 0.1 8.2 6 2 2 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM23064.1 - 3.8e-09 35.6 9.7 0.16 11.7 0.0 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM23064.1 - 1.3e-07 32.1 5.6 1.1 10.0 0.0 6.9 5 1 3 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM23064.1 - 1.5e-07 31.4 16.8 0.52 10.4 0.0 6.5 3 3 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM23064.1 - 3.7e-05 23.4 0.5 0.0044 16.8 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM23064.1 - 0.00014 21.4 6.0 11 6.0 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 GAM23064.1 - 0.00027 20.0 6.9 0.019 14.0 0.4 4.7 2 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM23064.1 - 0.00029 20.6 2.9 4.7 7.2 0.0 6.1 5 1 2 7 7 7 1 Tetratricopeptide repeat MIT PF04212.13 GAM23064.1 - 0.00084 19.1 0.7 37 4.3 0.0 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 GAM23064.1 - 0.00099 19.4 3.2 1.2e+02 3.5 0.2 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM23064.1 - 0.0012 18.6 0.5 1.2 9.1 0.0 3.6 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.7 GAM23064.1 - 0.0015 18.1 1.0 1.8 8.2 0.1 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF627) TPR_17 PF13431.1 GAM23064.1 - 0.031 14.4 6.4 9.5 6.7 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Porin_3 PF01459.17 GAM23065.1 - 4e-18 65.6 0.8 5.5e-18 65.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic porin DUF3722 PF12519.3 GAM23065.1 - 4.8e-06 25.9 1.2 0.00013 21.3 0.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) PGM_PMM_I PF02878.11 GAM23066.1 - 1.4e-35 121.8 0.4 2.2e-35 121.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 GAM23066.1 - 3.2e-27 94.8 0.0 5.7e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 GAM23066.1 - 6e-14 52.2 0.1 1.9e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 GAM23066.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SH3_9 PF14604.1 GAM23067.1 - 3.3e-24 84.1 1.0 1.8e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAM23067.1 - 1.6e-21 75.4 0.5 3.8e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAM23067.1 - 7.5e-19 66.9 0.3 1.1e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 GAM23067.1 - 2.9e-14 52.9 0.1 2.9e-14 52.9 0.1 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Beach PF02138.13 GAM23068.1 - 1.5e-108 362.3 0.9 1.5e-108 362.3 0.6 3.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM23068.1 - 1e-17 63.8 3.7 2.5e-17 62.6 0.0 2.8 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 GAM23068.1 - 1.7e-14 53.0 17.4 5e-06 26.1 1.4 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Mucin PF01456.12 GAM23068.1 - 0.00091 19.0 2.2 0.00091 19.0 1.5 4.8 7 0 0 7 7 7 1 Mucin-like glycoprotein DUF3419 PF11899.3 GAM23069.1 - 1.5e-14 53.5 0.2 2.5e-13 49.5 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 GAM23069.1 - 0.0047 16.6 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23069.1 - 0.007 16.8 0.0 1.2 9.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain AAA_assoc_C PF09821.4 GAM23069.1 - 0.0076 16.5 0.3 4.9 7.4 0.0 2.6 2 0 0 2 2 2 2 C-terminal AAA-associated domain Methyltransf_18 PF12847.2 GAM23069.1 - 0.051 14.1 0.1 3.1 8.3 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23069.1 - 0.075 13.5 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF1084 PF06454.6 GAM23070.1 - 1.4e-15 57.1 18.2 2.4e-14 53.0 12.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) NADH-u_ox-rdase PF10785.4 GAM23070.1 - 0.098 12.9 3.8 0.41 10.9 0.1 3.0 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit VanZ PF04892.7 GAM23070.1 - 1.4 8.8 8.3 1.9 8.4 0.7 2.9 2 1 0 2 2 2 0 VanZ like family Syndecan PF01034.15 GAM23070.1 - 9.6 5.9 5.8 43 3.8 0.9 3.0 3 0 0 3 3 3 0 Syndecan domain DUF4298 PF14131.1 GAM23071.1 - 0.07 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Ank_2 PF12796.2 GAM23072.1 - 1.2e-52 176.1 26.4 1.9e-11 44.1 0.3 6.8 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM23072.1 - 7.3e-35 118.7 14.8 0.0001 22.6 0.0 10.4 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM23072.1 - 2.6e-34 116.4 22.6 0.0088 16.2 0.0 14.7 4 3 11 15 15 15 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23072.1 - 1.4e-31 105.3 17.1 0.16 12.3 0.0 15.2 10 3 6 16 16 16 9 Ankyrin repeat Ank PF00023.25 GAM23072.1 - 5.1e-27 92.2 16.6 0.53 10.1 0.0 14.5 13 2 2 15 15 15 8 Ankyrin repeat DUF2493 PF10686.4 GAM23072.1 - 1.3e-05 24.6 3.4 5.1 6.7 0.0 5.5 5 1 1 6 6 6 2 Protein of unknown function (DUF2493) Rbsn PF11464.3 GAM23072.1 - 0.0097 15.4 0.7 1.2e+02 2.3 0.0 6.5 9 0 0 9 9 9 0 Rabenosyn Rab binding domain DUF2462 PF09495.5 GAM23072.1 - 0.012 16.2 0.1 20 5.9 0.0 5.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2462) BRCT PF00533.21 GAM23073.1 - 2.3e-10 40.4 0.1 1.9e-09 37.4 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM23073.1 - 0.00016 21.4 0.5 0.00032 20.5 0.3 1.5 1 0 0 1 1 1 1 twin BRCT domain p53-inducible11 PF14936.1 GAM23073.1 - 0.12 12.3 0.3 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF3627 PF12299.3 GAM23073.1 - 0.31 11.1 2.5 0.44 10.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3627) Peptidase_M28 PF04389.12 GAM23074.1 - 6.8e-12 45.4 0.1 1.7e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Pex2_Pex12 PF04757.9 GAM23075.1 - 2.3e-62 210.3 11.6 3e-62 210.0 8.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 GAM23075.1 - 2.3e-06 27.5 5.9 3.8e-06 26.8 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM23075.1 - 0.00038 20.0 2.3 0.0006 19.4 1.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM23075.1 - 0.0011 18.8 4.7 0.0019 18.0 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM23075.1 - 0.081 12.5 4.0 0.14 11.7 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM23075.1 - 0.34 10.8 7.3 0.6 10.0 5.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RhoGAP PF00620.22 GAM23077.1 - 2.5e-16 59.6 0.4 2.9e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain Ank_2 PF12796.2 GAM23078.1 - 2.7e-12 46.8 5.1 7.5e-08 32.6 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM23078.1 - 1.4e-10 40.3 3.7 0.98 9.8 0.1 5.4 2 2 3 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 GAM23078.1 - 1.4e-07 31.5 4.9 0.15 12.3 0.0 4.7 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM23078.1 - 4.2e-07 30.2 2.8 0.11 13.0 0.6 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM23078.1 - 0.0034 17.1 4.5 5.1 7.0 0.1 4.8 4 1 1 5 5 5 1 Ankyrin repeat Fer4_12 PF13353.1 GAM23078.1 - 0.09 12.8 0.3 4.8 7.2 0.0 2.6 3 0 0 3 3 3 0 4Fe-4S single cluster domain Viral_helicase1 PF01443.13 GAM23078.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PCI_Csn8 PF10075.4 GAM23082.1 - 0.024 14.4 0.8 0.036 13.8 0.6 1.3 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Coiled PF05710.7 GAM23083.1 - 0.31 11.5 11.7 0.38 11.2 8.1 1.1 1 0 0 1 1 1 0 Coiled coil UPF0444 PF15475.1 GAM23083.1 - 0.82 9.7 8.4 0.18 11.8 2.2 1.9 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 WH1 PF00568.18 GAM23084.1 - 1.4e-21 76.3 0.1 2e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 GAM23084.1 - 9.7e-17 61.1 0.1 2.7e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 GAM23084.1 - 2.9e-07 29.8 0.3 6.3e-07 28.8 0.2 1.5 1 0 0 1 1 1 1 WH2 motif Ribosomal_60s PF00428.14 GAM23084.1 - 0.003 17.9 5.6 0.003 17.9 3.9 2.4 3 0 0 3 3 3 1 60s Acidic ribosomal protein DCP1 PF06058.8 GAM23084.1 - 0.023 14.7 0.1 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family DUF3484 PF11983.3 GAM23084.1 - 0.033 15.0 1.1 0.066 14.0 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) DUF1681 PF07933.9 GAM23084.1 - 0.081 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) DUF2360 PF10152.4 GAM23084.1 - 0.24 11.6 27.0 0.66 10.2 0.1 3.2 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF1084 PF06454.6 GAM23085.1 - 3e-06 26.4 23.0 0.00028 20.0 15.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) WBP-1 PF11669.3 GAM23085.1 - 0.25 11.4 1.6 5.8 7.0 0.0 3.0 3 0 0 3 3 3 0 WW domain-binding protein 1 CD20 PF04103.10 GAM23085.1 - 1.9 8.3 13.1 0.23 11.3 2.6 3.2 1 1 1 3 3 3 0 CD20-like family DUF368 PF04018.8 GAM23085.1 - 9.6 5.3 17.5 0.96 8.5 6.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF368) Exonuc_VII_L PF02601.10 GAM23086.1 - 0.011 14.9 5.9 0.013 14.6 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Siva PF05458.7 GAM23086.1 - 0.11 12.0 26.0 0.088 12.3 17.2 1.7 1 1 0 1 1 1 0 Cd27 binding protein (Siva) LMBR1 PF04791.11 GAM23086.1 - 0.16 10.5 2.2 0.18 10.3 1.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-ZPR1 PF03367.8 GAM23087.1 - 1.2e-104 346.3 0.1 9.9e-53 177.5 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 GAM23087.1 - 0.0036 16.9 0.6 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-Mss51 PF13824.1 GAM23087.1 - 0.11 12.3 2.7 7.5 6.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1912 PF08930.5 GAM23087.1 - 0.15 12.2 0.9 5.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) zf-ISL3 PF14690.1 GAM23087.1 - 0.23 11.4 1.2 49 4.0 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.6 GAM23087.1 - 0.31 10.7 1.4 14 5.3 0.1 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 GAM23087.1 - 0.37 10.7 5.0 21 5.1 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain UPF0547 PF10571.4 GAM23087.1 - 0.71 9.6 7.6 5.9 6.6 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 FeS PF04060.8 GAM23087.1 - 1.1 8.8 4.7 2.8 7.6 0.1 2.7 3 0 0 3 3 3 0 Putative Fe-S cluster DNA_RNApol_7kD PF03604.8 GAM23087.1 - 6.2 6.3 10.9 16 5.0 0.0 4.1 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit RasGEF PF00617.14 GAM23088.1 - 7.1e-58 195.4 2.2 1.8e-57 194.1 1.5 1.8 1 0 0 1 1 1 1 RasGEF domain LRR_4 PF12799.2 GAM23088.1 - 9.1e-36 120.9 31.4 8.3e-08 31.6 0.1 8.3 5 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM23088.1 - 4.8e-30 103.0 33.6 4.8e-09 35.8 0.2 7.8 4 2 3 8 8 8 5 Leucine rich repeat Drf_GBD PF06371.8 GAM23088.1 - 2.4e-17 62.9 0.3 6.2e-17 61.5 0.2 1.8 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain RasGEF_N PF00618.15 GAM23088.1 - 1.3e-15 57.3 0.1 6.8e-15 55.0 0.1 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_1 PF00560.28 GAM23088.1 - 1.4e-15 54.9 28.6 0.23 11.6 0.1 13.1 13 0 0 13 13 13 4 Leucine Rich Repeat LRR_7 PF13504.1 GAM23088.1 - 7.2e-10 37.4 33.1 0.43 10.9 0.0 13.3 11 2 2 13 13 13 2 Leucine rich repeat Drf_FH3 PF06367.11 GAM23088.1 - 1.7e-08 34.1 0.0 4.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain LRR_6 PF13516.1 GAM23088.1 - 1.4e-06 27.7 12.6 1.1 9.5 0.0 8.7 9 1 0 9 9 9 2 Leucine Rich repeat HSP20 PF00011.16 GAM23089.1 - 7e-11 41.8 10.3 9.4e-08 31.8 0.1 3.3 2 1 2 4 4 4 2 Hsp20/alpha crystallin family Patched PF02460.13 GAM23089.1 - 0.16 9.8 8.1 0.17 9.7 5.6 1.1 1 0 0 1 1 1 0 Patched family Cellulose_synt PF03552.9 GAM23089.1 - 9.8 4.3 8.6 19 3.3 5.9 1.4 1 1 0 1 1 1 0 Cellulose synthase DUF4347 PF14252.1 GAM23090.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4347) GTPase_binding PF09027.5 GAM23090.1 - 0.071 12.7 0.3 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 GTPase binding Viral_DNA_bi PF02236.12 GAM23090.1 - 0.12 12.5 0.0 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain PI3K_rbd PF00794.13 GAM23092.1 - 2.3e-10 40.3 0.0 4.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain RA PF00788.18 GAM23092.1 - 0.04 14.4 0.3 0.086 13.3 0.0 1.8 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain FNIP PF05725.7 GAM23093.1 - 2.3e-56 187.4 40.4 3.7e-13 49.2 2.0 8.8 4 3 3 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 GAM23093.1 - 0.0021 17.9 6.2 6.1 6.8 0.1 5.2 4 1 4 8 8 8 3 Protein of unknown function (DUF1769) SR-25 PF10500.4 GAM23094.1 - 0.19 11.1 13.4 0.24 10.8 4.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.9 GAM23094.1 - 1.4 9.7 8.7 0.52 11.1 2.5 2.2 2 0 0 2 2 2 0 E4 protein GCC2_GCC3 PF07699.8 GAM23095.1 - 1.5e-14 53.2 56.8 2.1e-06 27.1 4.6 6.6 1 1 7 8 8 8 8 GCC2 and GCC3 NCD3G PF07562.9 GAM23095.1 - 0.00016 21.3 43.8 0.13 12.0 0.3 6.1 3 1 3 7 7 7 5 Nine Cysteines Domain of family 3 GPCR VSP PF03302.8 GAM23095.1 - 0.00027 19.6 43.5 0.0004 19.1 10.3 2.8 1 1 2 3 3 3 2 Giardia variant-specific surface protein RNA_pol_Rpb4 PF03874.11 GAM23096.1 - 1.2e-24 86.5 0.5 1.5e-24 86.2 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 PEPcase_2 PF14010.1 GAM23096.1 - 0.029 12.7 0.2 0.032 12.5 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Calici_MSP PF05752.6 GAM23098.1 - 0.16 11.5 0.4 0.25 10.9 0.3 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF972 PF06156.8 GAM23098.1 - 0.21 11.9 2.1 0.38 11.1 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) rve PF00665.21 GAM23099.1 - 2.4e-13 50.2 0.0 3.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Mucin PF01456.12 GAM23101.1 - 0.0086 15.8 19.6 0.016 14.9 13.6 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Totivirus_coat PF05518.6 GAM23101.1 - 1.1 7.0 7.2 1.5 6.5 5.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein WRC PF08879.5 GAM23102.1 - 0.0058 16.2 4.3 0.0058 16.2 3.0 2.3 1 1 1 2 2 2 1 WRC DUF1936 PF09151.5 GAM23102.1 - 0.69 9.4 3.1 11 5.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) AAA_16 PF13191.1 GAM23105.1 - 0.0088 16.0 0.0 0.039 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM23105.1 - 0.048 13.7 0.0 0.52 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 GAM23106.1 - 0.0092 15.6 0.8 0.028 14.1 0.0 2.2 3 0 0 3 3 3 1 Mitochondrial carrier protein DnaJ PF00226.26 GAM23106.1 - 0.23 11.2 1.5 0.4 10.4 0.2 2.1 2 1 0 2 2 2 0 DnaJ domain DnaJ PF00226.26 GAM23107.1 - 2.1e-07 30.5 1.0 5.4e-07 29.2 0.7 1.7 1 1 0 1 1 1 1 DnaJ domain RPT PF13446.1 GAM23107.1 - 0.00032 20.0 0.2 0.00063 19.0 0.1 1.4 1 0 0 1 1 1 1 A repeated domain in UCH-protein Mito_carr PF00153.22 GAM23107.1 - 0.0027 17.3 0.3 0.089 12.5 0.0 2.8 2 1 0 2 2 2 1 Mitochondrial carrier protein ABC2_membrane PF01061.19 GAM23108.1 - 2.1e-31 108.7 16.2 3.5e-31 108.0 11.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM23108.1 - 2.4e-25 89.4 0.0 3.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM23108.1 - 3.2e-07 30.6 0.1 0.012 15.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM23108.1 - 0.00029 20.2 0.2 0.00066 19.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM23108.1 - 0.00057 20.6 0.0 0.0012 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM23108.1 - 0.0018 17.7 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM23108.1 - 0.0028 17.9 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAM23108.1 - 0.0039 16.7 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM23108.1 - 0.0044 16.2 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 GAM23108.1 - 0.0055 15.9 0.0 0.091 11.9 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM23108.1 - 0.0061 16.5 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 GAM23108.1 - 0.043 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 GAM23108.1 - 0.044 13.7 0.1 0.33 10.8 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 GAM23108.1 - 0.047 12.4 0.1 0.075 11.7 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 GAM23108.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM23108.1 - 0.22 11.4 0.2 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain Myosin_TH1 PF06017.8 GAM23109.1 - 1.5e-06 27.6 0.4 2e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 Myosin tail bPH_3 PF14470.1 GAM23109.1 - 0.0031 17.7 0.2 2.8 8.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial PH domain SMN PF06003.7 GAM23110.1 - 6.6e-07 28.6 13.5 6.6e-07 28.6 9.3 3.0 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) DUF2217 PF10265.4 GAM23110.1 - 0.079 11.7 10.0 0.12 11.1 6.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3439 PF11921.3 GAM23110.1 - 3 7.6 10.6 0.17 11.6 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_S13 PF00416.17 GAM23111.1 - 5.2e-38 129.7 3.6 6.2e-38 129.5 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 GAM23111.1 - 0.024 13.1 0.0 0.025 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SOG2 PF10428.4 GAM23111.1 - 0.091 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SecY PF00344.15 GAM23114.1 - 5.3e-98 328.1 15.8 7e-98 327.7 11.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 GAM23114.1 - 2e-18 65.6 1.9 2.3e-18 65.3 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p GST_C PF00043.20 GAM23115.1 - 1.6e-14 53.6 0.0 3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM23115.1 - 6.2e-11 42.0 0.3 6.9e-10 38.6 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM23115.1 - 1.9e-09 37.5 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM23115.1 - 2.1e-09 37.2 0.0 4.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM23115.1 - 3.4e-08 33.6 0.0 6.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM23115.1 - 2.5e-07 31.1 0.1 3.9e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_L17 PF01196.14 GAM23116.1 - 5.9e-32 110.1 0.8 8.6e-32 109.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 CBS PF00571.23 GAM23117.1 - 5.7e-23 80.4 0.6 1.1e-09 37.9 0.1 3.4 3 0 0 3 3 3 3 CBS domain zf-B_box PF00643.19 GAM23118.1 - 6.3e-05 22.7 8.2 0.00012 21.9 5.7 1.4 1 0 0 1 1 1 1 B-box zinc finger FYVE_2 PF02318.11 GAM23118.1 - 0.049 13.5 1.1 0.08 12.8 0.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger PYST-C1 PF09690.5 GAM23118.1 - 0.95 9.1 6.8 2.9 7.5 4.7 1.8 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Acyl_transf_3 PF01757.17 GAM23119.1 - 4e-27 94.9 44.4 6.5e-27 94.2 30.8 1.3 1 0 0 1 1 1 1 Acyltransferase family SCFA_trans PF02667.9 GAM23120.1 - 1.3 7.6 6.8 1.5 7.5 4.7 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter SET PF00856.23 GAM23121.1 - 0.043 14.1 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 SET domain Dimer_Tnp_hAT PF05699.9 GAM23123.1 - 4.5e-11 42.2 0.0 1.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Chon_Sulph_att PF06566.6 GAM23124.1 - 0.076 12.6 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain LANC_like PF05147.8 GAM23125.1 - 1.9e-59 201.0 0.7 2.4e-59 200.7 0.5 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein zf-C3HC4_3 PF13920.1 GAM23126.1 - 2.5e-09 36.6 10.5 3.8e-09 36.0 7.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM23126.1 - 1.8e-07 31.0 13.1 3e-07 30.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM23126.1 - 3.9e-06 26.5 14.1 6.7e-06 25.8 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM23126.1 - 1.9e-05 24.2 12.0 4.7e-05 23.0 8.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM23126.1 - 2.8e-05 23.6 11.6 0.00028 20.4 8.5 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM23126.1 - 0.00066 19.5 9.9 0.022 14.5 7.9 2.4 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAM23126.1 - 0.0042 16.8 6.0 0.0077 16.0 4.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 GAM23126.1 - 0.0046 16.6 12.2 0.039 13.6 4.1 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 GAM23126.1 - 0.012 15.7 12.7 0.1 12.7 8.8 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-HIT PF04438.11 GAM23126.1 - 0.025 14.2 7.7 0.18 11.4 1.5 2.2 2 0 0 2 2 2 0 HIT zinc finger DUF2371 PF10177.4 GAM23126.1 - 0.036 13.9 0.3 0.048 13.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) ERM PF00769.14 GAM23126.1 - 0.072 12.6 13.5 0.11 12.0 9.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-RING_4 PF14570.1 GAM23126.1 - 0.088 12.4 9.8 0.17 11.5 6.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 GAM23126.1 - 0.13 12.1 13.9 0.85 9.5 5.7 2.9 1 1 1 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.1 GAM23126.1 - 0.17 11.4 9.6 0.49 9.9 6.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 AKNA PF12443.3 GAM23126.1 - 0.4 10.7 10.9 3 7.9 3.7 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor zf-C2H2_6 PF13912.1 GAM23126.1 - 0.65 9.9 0.2 0.65 9.9 0.1 3.0 4 0 0 4 4 3 0 C2H2-type zinc finger zf-Apc11 PF12861.2 GAM23126.1 - 1 9.2 7.7 5.5 6.8 5.3 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2346 PF09803.4 GAM23126.1 - 2.5 8.0 8.0 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) C1_4 PF07975.7 GAM23126.1 - 3.7 7.6 12.5 12 6.0 8.6 1.9 1 1 0 1 1 1 0 TFIIH C1-like domain zf-B_box PF00643.19 GAM23126.1 - 4.7 7.1 14.6 0.75 9.7 6.2 2.1 1 1 1 2 2 2 0 B-box zinc finger LCD1 PF09798.4 GAM23126.1 - 8.5 4.2 9.2 9.5 4.0 6.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DNA_repr_REX1B PF14966.1 GAM23127.1 - 2.7e-26 91.7 3.0 4.5e-25 87.8 0.4 2.1 2 0 0 2 2 2 1 DNA repair REX1-B IFT57 PF10498.4 GAM23127.1 - 0.047 12.4 7.5 0.16 10.6 5.2 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DASH_Dad3 PF08656.5 GAM23127.1 - 0.13 11.9 4.4 0.99 9.1 0.5 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad3 Syntaxin-6_N PF09177.6 GAM23127.1 - 0.17 12.2 4.0 2.6 8.5 0.1 2.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal FliJ PF02050.11 GAM23127.1 - 0.25 11.3 10.3 0.32 11.0 1.0 2.2 1 1 0 2 2 2 0 Flagellar FliJ protein WXG100 PF06013.7 GAM23127.1 - 0.68 9.9 3.3 5.8 7.0 0.4 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG UPF0139 PF03669.8 GAM23128.1 - 2.2e-20 72.0 0.1 2.6e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) LisH PF08513.6 GAM23129.1 - 7.5e-05 22.3 1.0 7.5e-05 22.3 0.7 1.9 2 0 0 2 2 2 1 LisH Glyco_hydro_59 PF02057.10 GAM23129.1 - 0.12 10.4 0.1 0.19 9.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Arm PF00514.18 GAM23130.1 - 6.9e-06 25.6 0.2 1.3e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat Cor1 PF04803.7 GAM23130.1 - 0.008 15.9 0.1 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region MYEOV2 PF15004.1 GAM23130.1 - 0.12 12.9 0.1 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Myeloma-overexpressed-like Arm PF00514.18 GAM23131.1 - 2.8e-08 33.2 0.1 0.0006 19.5 0.0 2.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat YniB PF14002.1 GAM23132.1 - 0.013 15.0 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 YniB-like protein IBB PF01749.15 GAM23133.1 - 6.6e-11 42.2 8.3 1.8e-10 40.8 5.8 1.7 1 1 0 1 1 1 1 Importin beta binding domain DUF1564 PF07600.6 GAM23133.1 - 0.075 12.3 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DUF771 PF05595.6 GAM23133.1 - 0.32 10.9 2.2 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF771) Peptidase_S46 PF10459.4 GAM23133.1 - 0.42 8.9 3.0 0.46 8.8 2.1 1.0 1 0 0 1 1 1 0 Peptidase S46 OmdA PF13376.1 GAM23133.1 - 0.5 10.0 3.5 2.4 7.8 0.0 2.6 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Synaphin PF05835.7 GAM23133.1 - 0.65 10.1 7.1 1.6 8.9 4.9 1.7 1 1 0 1 1 1 0 Synaphin protein Cna_B PF05738.8 GAM23134.1 - 2.3e-23 81.7 14.0 8.8e-06 25.4 0.0 7.2 6 0 0 6 6 6 5 Cna protein B-type domain DUF1933 PF09147.5 GAM23134.1 - 3.1e-05 23.5 0.0 5.4 6.3 0.0 4.9 4 0 0 4 4 4 3 Domain of unknown function (DUF1933) zf-4CXXC_R1 PF10497.4 GAM23135.1 - 3.7e-07 30.2 15.2 3.7e-07 30.2 10.5 2.3 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PWWP PF00855.12 GAM23135.1 - 4.6e-06 26.7 0.0 4.6e-06 26.7 0.0 2.7 3 0 0 3 3 3 1 PWWP domain JmjC PF02373.17 GAM23135.1 - 2.1e-05 24.7 1.3 0.00017 21.7 0.0 3.1 3 0 0 3 3 3 1 JmjC domain, hydroxylase Hydrolase PF00702.21 GAM23136.1 - 2.3e-44 152.3 0.1 4.8e-44 151.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 GAM23136.1 - 2.4e-41 141.2 0.4 2.4e-41 141.2 0.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 GAM23136.1 - 7.9e-15 55.5 0.1 1.8e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM23136.1 - 1.1e-06 28.3 0.2 7.7e-05 22.3 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 GAM23136.1 - 1.3e-05 25.2 0.2 0.0024 17.9 0.0 3.0 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD_2 PF13419.1 GAM23136.1 - 0.15 12.3 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 GAM23138.1 - 2.7e-62 210.2 0.0 5.1e-62 209.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23138.1 - 3.2e-43 147.6 0.0 5.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM23138.1 - 4e-05 22.7 0.1 0.0021 17.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM23138.1 - 0.0052 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sigma70_ner PF04546.8 GAM23138.1 - 0.97 9.0 10.6 0.027 14.0 2.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4307 PF14155.1 GAM23139.1 - 0.1 12.3 1.7 0.16 11.7 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) UAA PF08449.6 GAM23140.1 - 2e-42 145.2 31.4 3.6e-42 144.3 21.8 1.4 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAM23140.1 - 8.1e-09 35.2 14.1 8.1e-09 35.2 9.8 3.4 4 0 0 4 4 4 2 Triose-phosphate Transporter family EamA PF00892.15 GAM23140.1 - 2.1e-07 30.9 12.4 2.1e-07 30.9 8.6 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF4577 PF15145.1 GAM23140.1 - 0.9 9.4 0.0 0.9 9.4 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4577) Glyco_hydro_9 PF00759.14 GAM23141.1 - 8.1e-141 469.9 6.3 9.9e-141 469.6 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CBM49 PF09478.5 GAM23141.1 - 7.1e-16 58.0 0.1 1.3e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PT PF04886.7 GAM23141.1 - 3.3e-06 26.3 31.6 3.3e-06 26.3 21.9 2.3 1 1 1 2 2 2 2 PT repeat DUF4106 PF13388.1 GAM23141.1 - 0.0077 15.2 10.6 0.012 14.5 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) PRCC PF10253.4 GAM23141.1 - 1 10.0 4.4 1.8 9.2 3.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MSA-2c PF12238.3 GAM23141.1 - 2.2 7.9 7.2 3.4 7.2 5.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CBM49 PF09478.5 GAM23142.1 - 6.2e-12 45.4 1.3 6.2e-12 45.4 0.9 2.5 1 1 2 3 3 3 1 Carbohydrate binding domain CBM49 KIAA1328 PF15369.1 GAM23142.1 - 0.2 11.4 6.3 0.23 11.2 4.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 TFIIA PF03153.8 GAM23142.1 - 0.42 10.4 16.2 0.43 10.4 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AKAP2_C PF15304.1 GAM23142.1 - 0.66 9.5 9.5 0.8 9.2 6.6 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DUF2413 PF10310.4 GAM23142.1 - 0.8 8.4 14.5 0.93 8.2 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1675 PF07897.6 GAM23142.1 - 1.1 9.0 11.5 1.2 8.9 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PAP1 PF08601.5 GAM23142.1 - 1.8 8.1 26.6 2.2 7.9 18.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Period_C PF12114.3 GAM23142.1 - 6.2 6.3 15.4 9.3 5.7 10.7 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CCDC84 PF14968.1 GAM23142.1 - 8.6 5.7 13.7 10 5.5 9.5 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 Glyco_hydro_9 PF00759.14 GAM23143.1 - 3.1e-106 355.9 0.3 3.5e-106 355.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FNIP PF05725.7 GAM23144.1 - 8e-89 291.3 21.0 5.5e-16 58.2 0.2 8.0 4 1 7 12 12 12 10 FNIP Repeat Ras PF00071.17 GAM23145.1 - 7e-59 197.8 0.0 8.1e-59 197.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23145.1 - 6.7e-20 71.7 0.1 1.2e-19 70.9 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM23145.1 - 1.4e-09 37.4 0.0 1.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM23145.1 - 1.1e-06 28.2 0.2 1e-05 25.0 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM23145.1 - 0.00018 21.4 0.0 0.0002 21.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM23145.1 - 0.0095 15.5 1.0 0.11 11.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 GAM23145.1 - 0.022 14.0 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 GAM23145.1 - 0.04 12.9 0.0 0.09 11.7 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_25 PF13481.1 GAM23145.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 GAM23145.1 - 0.072 12.2 0.1 0.11 11.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 GAM23145.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAM23145.1 - 0.33 10.3 1.3 1.5 8.2 0.3 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein RhoGEF PF00621.15 GAM23146.1 - 4.8e-46 156.9 9.5 1.5e-44 152.0 0.4 3.0 3 0 0 3 3 3 2 RhoGEF domain IQ PF00612.22 GAM23146.1 - 0.00076 18.9 1.0 0.0016 17.9 0.7 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ca_chan_IQ PF08763.6 GAM23146.1 - 3 7.1 9.7 11 5.3 4.7 2.4 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain DUF4407 PF14362.1 GAM23146.1 - 4.1 6.2 5.8 7.2 5.4 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NAD_binding_10 PF13460.1 GAM23147.1 - 6.7e-11 42.5 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM23147.1 - 1.1e-08 34.8 0.3 2.7e-07 30.2 0.2 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM23147.1 - 6.4e-08 32.1 0.7 2.1e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family 3HCDH_N PF02737.13 GAM23147.1 - 3.8e-05 23.4 2.0 0.0019 17.8 1.4 2.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 GAM23147.1 - 0.00013 21.8 0.4 0.00031 20.7 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 GAM23147.1 - 0.00031 21.1 1.0 0.00053 20.3 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 GAM23147.1 - 0.00065 19.5 0.2 0.0014 18.4 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 GAM23147.1 - 0.0015 18.4 0.5 0.0015 18.4 0.4 1.7 2 0 0 2 2 2 1 TrkA-N domain Polysacc_synt_2 PF02719.10 GAM23147.1 - 0.0048 15.8 0.1 0.029 13.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 GAM23147.1 - 0.0056 15.7 0.4 0.013 14.4 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 GAM23147.1 - 0.011 14.6 0.3 0.03 13.2 0.0 1.9 2 1 1 3 3 3 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 GAM23147.1 - 0.038 12.7 0.5 3.2 6.3 0.0 2.1 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 GAM23147.1 - 0.043 13.7 0.1 0.11 12.4 0.1 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 GAM23147.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DXP_reductoisom PF02670.11 GAM23147.1 - 0.17 12.4 0.7 0.45 11.0 0.2 2.0 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PS_Dcarbxylase PF02666.10 GAM23148.1 - 8.3e-64 214.6 0.0 1e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AIRS_C PF02769.17 GAM23149.1 - 2.8e-21 76.1 0.0 4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 GAM23149.1 - 3e-07 30.5 0.0 6.6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ELYS PF13934.1 GAM23151.1 - 2e-23 83.2 3.2 4.1e-23 82.2 2.2 1.5 1 0 0 1 1 1 1 Nuclear pore complex assembly PIP5K PF01504.13 GAM23152.1 - 8.2e-60 202.0 0.6 2.5e-59 200.4 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Reticulon PF02453.12 GAM23153.1 - 2.3e-33 115.1 9.9 2.3e-33 115.1 6.8 2.1 2 0 0 2 2 2 1 Reticulon Apolipoprotein PF01442.13 GAM23153.1 - 0.00016 21.2 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.1 GAM23153.1 - 0.007 16.4 3.1 0.016 15.3 2.1 1.6 1 0 0 1 1 1 1 MT0933-like antitoxin protein DUF2884 PF11101.3 GAM23153.1 - 0.0079 15.5 0.5 0.14 11.5 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) DUF2120 PF09893.4 GAM23153.1 - 0.015 15.2 2.8 0.4 10.6 1.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF883 PF05957.8 GAM23153.1 - 0.017 15.5 3.0 0.037 14.4 2.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) HHH_3 PF12836.2 GAM23153.1 - 0.021 14.7 0.2 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif phiKZ_IP PF12699.2 GAM23153.1 - 0.029 13.2 0.2 0.029 13.2 0.2 1.4 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins YtxH PF12732.2 GAM23153.1 - 0.03 14.6 6.4 0.081 13.2 4.4 1.7 1 0 0 1 1 1 0 YtxH-like protein NAAA-beta PF15508.1 GAM23153.1 - 0.094 13.0 1.5 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase VIT1 PF01988.14 GAM23153.1 - 0.18 11.2 3.9 0.062 12.7 0.4 1.8 1 1 0 2 2 2 0 VIT family DUF964 PF06133.6 GAM23153.1 - 0.33 10.9 5.1 1.8 8.6 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF964) Sec8_exocyst PF04048.9 GAM23153.1 - 0.39 10.3 5.2 0.22 11.1 2.0 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.6 GAM23153.1 - 0.59 10.1 7.9 1 9.3 4.9 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Orbi_NS3 PF01616.11 GAM23153.1 - 2.3 7.1 6.6 0.33 9.8 0.2 2.3 2 1 0 2 2 2 0 Orbivirus NS3 Ribosomal_S5 PF00333.15 GAM23154.1 - 4.6e-12 45.4 1.8 9.9e-12 44.4 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PLA2_B PF01735.13 GAM23155.1 - 0.03 12.4 0.1 0.03 12.4 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain TUDOR PF00567.19 GAM23158.1 - 4.5e-09 36.1 0.7 2.5e-08 33.7 0.0 2.5 3 1 1 4 4 4 1 Tudor domain SMN PF06003.7 GAM23158.1 - 5.7e-06 25.6 3.9 5.7e-06 25.6 2.7 2.1 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) Agenet PF05641.7 GAM23158.1 - 0.0012 18.9 0.1 0.0037 17.3 0.1 1.8 1 0 0 1 1 1 1 Agenet domain Med3 PF11593.3 GAM23158.1 - 0.01 15.0 11.8 0.018 14.2 8.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2730 PF10805.3 GAM23158.1 - 0.011 15.5 0.8 0.011 15.5 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF1409 PF07197.7 GAM23158.1 - 0.19 11.7 2.7 0.39 10.8 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1409) Atg14 PF10186.4 GAM23158.1 - 0.22 10.4 11.5 0.2 10.5 0.9 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IFT20 PF14931.1 GAM23158.1 - 0.65 9.9 8.2 0.054 13.3 1.1 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Allexi_40kDa PF05549.6 GAM23158.1 - 5.3 6.2 14.4 0.31 10.3 3.7 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein AAA_23 PF13476.1 GAM23158.1 - 5.8 7.1 14.5 2.3 8.5 0.6 2.2 2 0 0 2 2 2 0 AAA domain HAD_2 PF13419.1 GAM23159.1 - 1.9e-24 86.8 0.0 2.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM23159.1 - 1.8e-06 27.5 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM23159.1 - 0.011 16.1 0.0 0.4 11.0 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 GAM23159.1 - 0.012 15.3 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase Ras PF00071.17 GAM23160.1 - 1.3e-60 203.4 0.1 1.6e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23160.1 - 7.8e-18 65.1 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM23160.1 - 2.2e-15 56.3 0.0 2.8e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM23160.1 - 2.2e-05 23.7 0.1 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM23160.1 - 0.0009 18.7 0.1 0.0035 16.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM23160.1 - 0.0017 18.2 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM23160.1 - 0.014 14.6 0.0 0.077 12.2 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 GAM23160.1 - 0.02 14.1 0.1 0.024 13.8 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAM23160.1 - 0.038 14.1 0.0 0.078 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 GAM23160.1 - 0.045 13.1 0.0 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF258 PF03193.11 GAM23160.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 GAM23160.1 - 0.11 11.5 0.0 0.23 10.4 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 GAM23160.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM23160.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Glyco_transf_41 PF13844.1 GAM23161.1 - 1.4e-51 174.9 0.9 3e-27 94.7 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_20 PF14561.1 GAM23161.1 - 0.032 14.3 0.2 2.8 8.1 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM23161.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ZZ PF00569.12 GAM23162.1 - 9e-12 44.3 5.5 1.5e-11 43.6 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 GAM23162.1 - 5e-11 42.4 0.1 9.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM23162.1 - 1.5e-06 28.2 0.0 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Arrestin_N PF00339.24 GAM23162.1 - 0.034 13.9 0.0 0.034 13.9 0.0 2.5 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain SIT PF15330.1 GAM23162.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.3 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4355 PF14265.1 GAM23162.1 - 0.2 11.6 0.2 0.2 11.6 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4355) Romo1 PF10247.4 GAM23163.1 - 1e-12 48.0 9.7 1.3e-12 47.6 6.8 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 ABC_membrane PF00664.18 GAM23164.1 - 6.7e-43 147.0 26.8 6.7e-43 147.0 18.6 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.17 GAM23164.1 - 8.9e-39 133.3 4.2 8.9e-39 133.3 2.9 2.3 2 0 0 2 2 2 1 Subtilase family ABC_tran PF00005.22 GAM23164.1 - 4.7e-32 111.1 0.4 1.4e-31 109.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 GAM23164.1 - 2.9e-07 29.9 4.1 1.2e-06 27.9 1.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM23164.1 - 5.6e-06 26.5 0.2 0.0037 17.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain Protocadherin PF08374.6 GAM23164.1 - 0.0035 17.0 1.7 0.24 11.0 0.0 2.6 2 0 0 2 2 2 1 Protocadherin Zeta_toxin PF06414.7 GAM23164.1 - 0.0042 16.2 0.0 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 GAM23164.1 - 0.0059 17.4 0.0 0.025 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM23164.1 - 0.0096 16.0 0.1 0.049 13.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM23164.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAM23164.1 - 0.018 14.5 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain EphA2_TM PF14575.1 GAM23164.1 - 9.2 6.7 6.6 10 6.6 0.0 3.8 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF221 PF02714.10 GAM23165.1 - 9.6e-82 274.4 22.2 9.6e-82 274.4 15.4 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM23165.1 - 1.8e-38 131.6 4.6 1.8e-38 131.6 3.2 3.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAM23165.1 - 0.0053 17.2 0.4 0.0096 16.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2120 PF09893.4 GAM23166.1 - 0.069 13.1 0.2 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3439 PF11921.3 GAM23166.1 - 0.28 10.9 5.2 0.67 9.7 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Nucleoside_tran PF01733.13 GAM23167.1 - 1.1e-32 113.4 23.4 1.8e-32 112.7 11.2 2.8 2 1 0 2 2 2 1 Nucleoside transporter EVI2A PF05399.6 GAM23167.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) YfhO PF09586.5 GAM23167.1 - 0.71 7.8 26.1 1.1 7.1 5.7 2.2 2 0 0 2 2 2 0 Bacterial membrane protein YfhO ATP-synt_8 PF00895.15 GAM23167.1 - 0.98 9.6 0.0 0.98 9.6 0.0 4.9 6 1 0 6 6 6 0 ATP synthase protein 8 RhoGAP PF00620.22 GAM23168.1 - 2.8e-36 124.4 0.1 5.9e-36 123.3 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.6 GAM23168.1 - 0.0044 16.8 1.7 15 6.0 0.0 5.2 5 0 0 5 5 5 0 Two component regulator propeller DUF605 PF04652.11 GAM23168.1 - 0.049 13.0 26.0 0.073 12.4 18.0 1.1 1 0 0 1 1 1 0 Vta1 like Mem_trans PF03547.13 GAM23168.1 - 0.064 11.5 1.5 0.09 11.0 1.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Raftlin PF15250.1 GAM23168.1 - 0.74 8.2 10.8 1.4 7.3 7.5 1.4 1 0 0 1 1 1 0 Raftlin CobT PF06213.7 GAM23168.1 - 0.94 8.5 15.1 1.6 7.7 10.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF572 PF04502.8 GAM23168.1 - 1.1 8.4 26.6 1.8 7.7 18.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Menin PF05053.8 GAM23168.1 - 1.2 7.2 12.2 1.8 6.6 8.5 1.2 1 0 0 1 1 1 0 Menin DUF1510 PF07423.6 GAM23168.1 - 1.2 8.4 20.2 2.9 7.1 14.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 GAM23168.1 - 4.4 6.4 10.2 10 5.1 7.1 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 GAM23168.1 - 4.4 7.1 17.7 7.9 6.2 12.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 GAM23168.1 - 5.1 4.9 15.1 8.2 4.3 10.5 1.3 1 0 0 1 1 1 0 CDC45-like protein EAP30 PF04157.11 GAM23169.1 - 1e-63 214.4 1.3 1.2e-63 214.3 0.9 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Activator-TraM PF11657.3 GAM23169.1 - 0.095 12.1 0.7 0.19 11.1 0.5 1.4 1 0 0 1 1 1 0 Transcriptional activator TraM DUF4479 PF14794.1 GAM23169.1 - 0.25 10.8 4.0 0.34 10.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4479) zf-B_box PF00643.19 GAM23170.1 - 6.7e-10 38.7 6.7 6.7e-10 38.7 4.6 1.9 2 0 0 2 2 2 1 B-box zinc finger MtlR PF05068.7 GAM23170.1 - 0.001 18.5 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Mannitol repressor IBR PF01485.16 GAM23170.1 - 2 8.3 7.1 0.77 9.6 3.0 1.7 2 0 0 2 2 2 0 IBR domain CBFD_NFYB_HMF PF00808.18 GAM23171.1 - 6.8e-15 54.8 0.7 1.2e-14 54.1 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CDC45 PF02724.9 GAM23171.1 - 0.0028 15.7 6.9 0.0044 15.1 4.8 1.3 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.7 GAM23171.1 - 0.016 14.3 7.8 0.026 13.6 5.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRN3 PF05327.6 GAM23171.1 - 0.042 11.9 3.5 0.081 11.0 2.4 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 GAM23171.1 - 0.062 12.9 15.6 0.1 12.2 9.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Histone PF00125.19 GAM23171.1 - 0.082 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIIF_alpha PF05793.7 GAM23171.1 - 1.3 7.3 27.6 0.023 13.1 13.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 GAM23171.1 - 1.7 6.4 20.0 0.47 8.3 11.5 1.7 1 1 0 1 1 1 0 Nop14-like family BAR PF03114.13 GAM23172.1 - 6.1e-09 35.7 4.2 9.5e-09 35.1 2.9 1.3 1 0 0 1 1 1 1 BAR domain DUF717 PF05338.7 GAM23172.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF717) GATA PF00320.22 GAM23173.1 - 2.6e-15 55.4 3.1 5.5e-15 54.4 2.2 1.6 1 0 0 1 1 1 1 GATA zinc finger A2L_zn_ribbon PF08792.5 GAM23173.1 - 2.2 7.8 6.4 13 5.4 0.3 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain SART-1 PF03343.8 GAM23173.1 - 4.4 5.5 11.9 6.8 4.9 8.3 1.2 1 0 0 1 1 1 0 SART-1 family Mitofilin PF09731.4 GAM23173.1 - 9.5 4.7 11.2 13 4.2 7.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TPR_12 PF13424.1 GAM23174.1 - 1.6e-39 133.6 9.8 8.7e-13 48.0 0.4 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 GAM23174.1 - 7.6e-12 44.7 10.0 0.004 16.7 0.1 5.2 3 1 2 5 5 5 3 TPR repeat TPR_10 PF13374.1 GAM23174.1 - 8.4e-11 41.4 9.2 4.9e-05 23.1 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM23174.1 - 7.2e-10 38.0 15.1 0.049 13.5 0.0 7.2 8 0 0 8 8 6 4 Tetratricopeptide repeat TIG PF01833.19 GAM23174.1 - 8.3e-10 38.5 2.8 2e-09 37.2 1.9 1.7 1 0 0 1 1 1 1 IPT/TIG domain NACHT PF05729.7 GAM23174.1 - 1.1e-09 38.2 0.0 1.1e-09 38.2 0.0 3.0 2 1 0 2 2 1 1 NACHT domain TPR_1 PF00515.23 GAM23174.1 - 1.4e-09 37.1 18.7 0.0031 17.0 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat DUF4062 PF13271.1 GAM23174.1 - 1.6e-07 31.2 0.0 1.5e-06 28.1 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) TPR_8 PF13181.1 GAM23174.1 - 4.2e-06 26.1 14.9 0.17 11.6 0.1 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 GAM23174.1 - 7.6e-06 26.0 2.4 1.7e-05 24.9 0.0 2.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM23174.1 - 4.3e-05 23.6 0.3 0.00067 19.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain TPR_7 PF13176.1 GAM23174.1 - 0.00018 21.0 11.7 4.9 7.1 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM23174.1 - 0.00068 20.0 2.0 65 4.5 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat PAT1 PF09770.4 GAM23174.1 - 0.0021 16.4 81.0 0.0042 15.4 56.1 1.5 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AAA_29 PF13555.1 GAM23174.1 - 0.021 14.3 0.0 0.053 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThiF PF00899.16 GAM23174.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family KAP_NTPase PF07693.9 GAM23174.1 - 0.058 12.3 0.1 0.058 12.3 0.0 3.2 3 1 1 4 4 4 0 KAP family P-loop domain AAA_25 PF13481.1 GAM23174.1 - 0.11 11.9 0.0 0.42 9.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM23174.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.7 2 1 0 2 2 1 0 ABC transporter Miro PF08477.8 GAM23174.1 - 0.42 11.1 0.0 0.42 11.1 0.0 2.9 2 1 0 2 2 1 0 Miro-like protein Med15 PF09606.5 GAM23174.1 - 3.2 5.8 107.2 5.5 5.0 74.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TatD_DNase PF01026.16 GAM23175.1 - 4.4e-42 144.0 0.0 1.1e-41 142.7 0.0 1.6 2 0 0 2 2 2 1 TatD related DNase TT_ORF2 PF02957.10 GAM23175.1 - 0.051 14.2 4.6 0.15 12.7 3.2 1.8 1 0 0 1 1 1 0 TT viral ORF2 Yippee-Mis18 PF03226.9 GAM23175.1 - 0.067 13.2 1.2 0.36 10.8 0.7 2.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Amidohydro_2 PF04909.9 GAM23175.1 - 0.099 12.1 0.0 0.54 9.7 0.0 2.0 2 1 0 2 2 2 0 Amidohydrolase Lar_restr_allev PF14354.1 GAM23175.1 - 0.65 10.3 3.8 3.2 8.1 0.2 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar Sigma70_ner PF04546.8 GAM23175.1 - 2.6 7.6 17.2 0.17 11.4 6.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 GAM23175.1 - 2.8 8.3 19.0 7.1 7.0 7.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 GAM23175.1 - 3.2 7.3 13.3 0.47 10.1 4.6 2.3 2 0 0 2 2 2 0 FAM176 family GST_N PF02798.15 GAM23176.1 - 4.7e-11 42.7 0.0 8.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM23176.1 - 3.4e-06 26.9 0.0 1.7e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM23176.1 - 0.00011 22.6 0.0 0.00024 21.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM23176.1 - 0.0066 16.6 0.1 0.015 15.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM23176.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EB PF01683.13 GAM23177.1 - 0.0032 17.4 2.3 0.0078 16.2 1.6 1.6 1 0 0 1 1 1 1 EB module PRKCSH-like PF12999.2 GAM23177.1 - 0.22 11.1 2.4 0.41 10.1 1.6 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like CorA PF01544.13 GAM23178.1 - 7e-45 153.2 8.1 9.8e-45 152.8 5.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1129 PF06570.6 GAM23178.1 - 0.016 14.5 0.1 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF566 PF04484.7 GAM23178.1 - 0.48 9.8 3.9 1.9 7.9 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF566) Mem_trans PF03547.13 GAM23178.1 - 1.7 6.8 7.9 1.5 7.0 1.3 2.1 2 0 0 2 2 2 0 Membrane transport protein Copper-bind PF00127.15 GAM23179.1 - 0.00065 19.8 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family PH_8 PF15409.1 GAM23179.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2264 PF10022.4 GAM23179.1 - 0.071 11.7 0.0 0.084 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Ank_2 PF12796.2 GAM23180.1 - 2.1e-15 56.8 3.2 6.2e-06 26.4 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM23180.1 - 7.2e-08 31.9 5.8 0.86 10.0 0.1 6.7 4 2 2 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 GAM23180.1 - 1.5e-07 31.4 8.4 0.26 11.5 0.1 5.8 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM23180.1 - 1.3e-05 25.5 11.7 0.0057 17.1 0.1 5.6 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM23180.1 - 0.00085 19.0 10.5 1.4 8.8 0.0 6.7 9 0 0 9 9 9 2 Ankyrin repeat DUF521 PF04412.8 GAM23180.1 - 0.081 11.4 0.0 0.25 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF521) DUF914 PF06027.7 GAM23181.1 - 1.5e-09 37.2 12.4 3.4e-09 36.0 5.2 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 GAM23181.1 - 1.6e-07 31.3 37.0 1.8e-07 31.2 4.5 3.0 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAM23181.1 - 0.001 19.2 2.3 0.001 19.2 1.6 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 GAM23181.1 - 0.0061 16.2 27.1 0.018 14.6 6.5 3.5 3 2 1 4 4 4 3 Triose-phosphate Transporter family GWT1 PF06423.7 GAM23181.1 - 0.03 14.4 11.2 0.084 12.9 1.6 3.1 1 1 2 3 3 3 0 GWT1 SHMT PF00464.14 GAM23182.1 - 6.2e-184 610.9 0.0 7.3e-184 610.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 GAM23182.1 - 0.00011 21.0 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM23182.1 - 0.0014 17.8 0.0 0.003 16.7 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.16 GAM23182.1 - 0.027 14.3 0.0 0.076 12.9 0.0 1.8 1 0 0 1 1 1 0 Macro domain Aminotran_1_2 PF00155.16 GAM23182.1 - 0.11 11.3 0.0 0.37 9.6 0.0 2.0 1 1 0 1 1 1 0 Aminotransferase class I and II FNIP PF05725.7 GAM23183.1 - 1.8e-58 194.2 2.6 6.6e-11 41.9 0.0 8.0 3 3 8 12 12 12 11 FNIP Repeat LRR_1 PF00560.28 GAM23183.1 - 0.1 12.6 2.0 30 5.1 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat HEAT PF02985.17 GAM23184.1 - 1.5e-22 77.5 2.3 4.5e-06 26.2 0.0 10.5 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.1 GAM23184.1 - 5.7e-18 64.9 0.0 7.6e-06 26.1 0.0 7.5 5 2 4 9 9 9 4 HEAT repeats IBN_N PF03810.14 GAM23184.1 - 4.2e-16 58.6 0.8 1.8e-15 56.6 0.6 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 GAM23184.1 - 7.3e-16 58.1 0.0 7.7e-08 32.5 0.0 7.4 9 0 0 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM23184.1 - 3e-13 49.9 1.5 0.0055 17.0 0.0 7.1 4 3 2 7 7 7 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 GAM23184.1 - 1e-09 38.1 0.7 0.098 11.9 0.0 5.0 4 1 1 5 5 5 3 CLASP N terminal Arm PF00514.18 GAM23184.1 - 2.1e-08 33.7 1.8 0.00022 20.9 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 GAM23184.1 - 6.5e-06 24.6 5.9 0.00012 20.5 0.2 3.2 3 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit MMS19_C PF12460.3 GAM23184.1 - 0.0013 17.5 7.7 0.14 10.8 0.5 3.7 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal Xpo1 PF08389.7 GAM23184.1 - 0.018 14.9 8.0 0.88 9.4 0.1 4.8 4 1 0 4 4 4 0 Exportin 1-like protein MMS19_N PF14500.1 GAM23184.1 - 0.032 13.4 0.8 7.4 5.7 0.0 3.9 4 1 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II FNIP PF05725.7 GAM23185.1 - 1.2e-110 361.2 40.2 7.7e-13 48.1 0.3 12.3 8 2 5 13 13 13 13 FNIP Repeat Kelch_6 PF13964.1 GAM23185.1 - 2.6e-05 24.1 0.5 0.0019 18.3 0.0 3.4 2 1 1 3 3 3 1 Kelch motif Kelch_4 PF13418.1 GAM23185.1 - 0.0003 20.5 0.0 0.0011 18.6 0.0 2.0 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM23185.1 - 0.033 13.9 0.2 9.4 6.1 0.0 3.4 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 GAM23186.1 - 2.4e-09 36.9 5.5 3.7e-05 23.6 0.0 4.4 3 2 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM23186.1 - 5.9e-08 32.3 2.1 0.00016 21.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM23186.1 - 0.019 14.5 7.3 0.036 13.6 0.0 3.9 5 1 0 5 5 5 0 Kelch motif Kelch_5 PF13854.1 GAM23186.1 - 0.13 12.2 3.3 17 5.5 0.0 3.9 4 0 0 4 4 4 0 Kelch motif LOH1CR12 PF10158.4 GAM23187.1 - 0.0088 15.8 2.0 0.011 15.5 0.8 1.6 1 1 1 2 2 2 1 Tumour suppressor protein Baculo_PEP_C PF04513.7 GAM23187.1 - 0.036 13.8 0.1 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 GAM23187.1 - 0.051 13.4 0.9 0.14 11.9 0.3 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AF0941-like PF14591.1 GAM23187.1 - 0.059 13.4 2.0 0.095 12.7 0.4 1.9 1 1 1 2 2 2 0 AF0941-like HSP20 PF00011.16 GAM23188.1 - 5.5e-20 71.1 0.0 2.9e-19 68.8 0.0 2.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family E1-E2_ATPase PF00122.15 GAM23189.1 - 7.6e-56 188.7 0.5 7.6e-56 188.7 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM23189.1 - 4.3e-36 124.1 8.8 4.3e-36 124.1 6.1 3.4 4 1 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM23189.1 - 1.1e-22 81.4 0.1 3.5e-22 79.8 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM23189.1 - 1.7e-10 40.6 0.0 1.1e-08 34.9 0.0 3.2 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM23189.1 - 2.6e-09 37.5 0.0 2.3e-08 34.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM23189.1 - 2e-08 34.1 4.1 5.1e-05 22.9 0.9 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM23189.1 - 2e-08 33.5 0.0 5.3e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF962 PF06127.6 GAM23189.1 - 0.39 10.6 2.9 0.58 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF962) GpcrRhopsn4 PF10192.4 GAM23190.1 - 3.5e-75 252.5 18.6 3.5e-75 252.5 12.9 1.5 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 GAM23190.1 - 0.0017 17.3 16.9 0.0056 15.6 11.7 1.9 1 1 0 1 1 1 1 Lung seven transmembrane receptor PufQ PF05398.6 GAM23190.1 - 0.011 15.7 4.2 0.39 10.7 0.1 3.4 3 0 0 3 3 3 0 PufQ cytochrome subunit UFD1 PF03152.9 GAM23192.1 - 3.4e-67 224.9 0.1 4.2e-67 224.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 BSP_II PF05432.6 GAM23192.1 - 0.0056 15.9 2.3 0.008 15.4 1.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) T2SM PF04612.7 GAM23193.1 - 1.3 8.8 4.4 3.2 7.5 0.1 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M bZIP_1 PF00170.16 GAM23194.1 - 9.7e-05 22.2 11.7 9.7e-05 22.2 8.1 3.3 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.10 GAM23194.1 - 0.0017 18.1 12.0 0.0017 18.1 8.3 5.3 4 0 0 4 4 4 1 Basic region leucine zipper TIG PF01833.19 GAM23195.1 - 1.2e-88 291.2 376.5 4.2e-13 49.1 4.9 25.7 23 1 0 23 23 23 20 IPT/TIG domain Qn_am_d_aIII PF09099.5 GAM23195.1 - 3.9e-07 30.2 21.8 3e-05 24.2 0.1 9.2 10 0 0 10 10 10 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III CHCH PF06747.8 GAM23198.1 - 0.0012 18.7 1.9 0.0017 18.1 0.4 1.8 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 GAM23198.1 - 0.015 15.4 0.4 0.024 14.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Dicty_CTDC PF00526.13 GAM23199.1 - 9e-13 47.7 35.5 7.2e-07 28.9 5.3 13.8 14 0 0 14 14 14 7 Dictyostelium (slime mold) repeat PA14 PF07691.7 GAM23199.1 - 9.1e-10 38.3 0.1 1.6e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 PA14 domain Integrin_b_cyt PF08725.6 GAM23199.1 - 4.9 6.6 7.4 0.56 9.6 1.4 2.0 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Ras PF00071.17 GAM23203.1 - 8.7e-57 191.0 0.2 1.1e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23203.1 - 5.2e-20 72.1 0.0 8.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM23203.1 - 2.1e-09 36.8 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM23203.1 - 2.3e-06 27.2 0.3 8e-06 25.4 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM23203.1 - 8e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM23203.1 - 0.00079 18.2 0.1 0.1 11.2 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit FERM_M PF00373.13 GAM23204.1 - 8e-45 152.0 14.0 5.8e-23 81.4 0.2 3.5 3 0 0 3 3 3 2 FERM central domain FERM_N PF09379.5 GAM23204.1 - 2e-31 107.8 3.5 3.3e-14 52.6 0.0 4.1 5 0 0 5 5 5 3 FERM N-terminal domain IRS PF02174.12 GAM23204.1 - 2.4e-06 27.0 1.1 0.0011 18.5 0.0 2.9 3 0 0 3 3 3 2 PTB domain (IRS-1 type) FERM_C PF09380.5 GAM23204.1 - 3.4e-05 23.9 0.2 0.24 11.6 0.0 3.1 2 0 0 2 2 2 2 FERM C-terminal PH-like domain RA PF00788.18 GAM23204.1 - 0.00045 20.6 0.1 0.23 11.9 0.0 3.2 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain ACBP PF00887.14 GAM23204.1 - 0.00065 19.3 0.1 0.48 10.1 0.0 3.0 2 0 0 2 2 2 2 Acyl CoA binding protein Rad60-SLD PF11976.3 GAM23204.1 - 0.0073 15.9 0.9 0.65 9.7 0.3 3.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Cytokin_check_N PF10407.4 GAM23204.1 - 0.018 14.6 0.2 0.78 9.3 0.0 2.8 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus DUF3439 PF11921.3 GAM23204.1 - 0.36 10.5 9.8 0.94 9.2 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 GAM23204.1 - 1.1 8.9 12.3 0.037 13.7 4.2 1.7 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Sugar_tr PF00083.19 GAM23205.1 - 9.3e-85 284.8 43.4 4e-82 276.1 30.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM23205.1 - 1e-33 116.5 41.1 7e-28 97.3 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM23205.1 - 2.2e-11 42.8 15.8 2.2e-11 42.8 11.0 3.0 1 1 2 3 3 3 2 MFS/sugar transport protein Rick_17kDa_Anti PF05433.10 GAM23205.1 - 0.21 11.2 11.1 1.1 8.9 6.6 2.8 2 1 0 2 2 2 0 Glycine zipper 2TM domain Kelch_4 PF13418.1 GAM23206.1 - 2.2e-10 40.1 2.1 4e-08 32.9 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM23206.1 - 4e-07 29.9 8.1 0.017 15.2 0.0 4.6 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM23206.1 - 7.7e-06 25.9 0.5 0.042 14.0 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM23206.1 - 0.038 13.5 0.0 0.038 13.5 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 GAM23206.1 - 0.067 12.9 1.0 8.5 6.3 0.0 3.4 4 0 0 4 4 4 0 Kelch motif PEGA PF08308.6 GAM23207.1 - 2.8e-06 27.0 0.0 1.7e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 PEGA domain IncA PF04156.9 GAM23207.1 - 0.53 9.8 0.0 0.82 9.2 0.0 1.2 1 0 0 1 1 1 0 IncA protein Telomere_Sde2 PF13019.1 GAM23208.1 - 8.5e-29 100.3 5.7 8.5e-29 100.3 4.0 2.0 1 1 0 2 2 2 1 Telomere stability and silencing Latarcin PF10279.4 GAM23208.1 - 0.00052 20.1 1.2 0.0013 18.8 0.4 2.0 1 1 0 1 1 1 1 Latarcin precursor Mucin PF01456.12 GAM23208.1 - 0.024 14.3 12.2 0.021 14.5 7.6 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Herpes_capsid PF06112.6 GAM23208.1 - 0.081 12.9 3.1 0.14 12.1 2.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF3439 PF11921.3 GAM23208.1 - 0.25 11.0 5.8 0.51 10.1 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) eIF-3c_N PF05470.7 GAM23208.1 - 0.55 8.2 9.0 0.82 7.6 6.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Plasmodium_Vir PF05795.6 GAM23208.1 - 0.97 8.5 6.0 1.8 7.7 4.2 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein SSP160 PF06933.6 GAM23208.1 - 1.2 7.0 15.1 1.6 6.6 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2057 PF09829.4 GAM23208.1 - 7.2 6.2 12.7 3.6 7.2 6.9 1.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Pkinase PF00069.20 GAM23209.1 - 4.5e-26 91.5 0.0 7.9e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 GAM23209.1 - 1.3e-14 53.4 3.9 0.0026 17.5 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 GAM23209.1 - 9.4e-11 41.2 0.0 1.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Poty_PP PF08440.5 GAM23209.1 - 0.3 10.1 2.8 5.1 6.0 0.6 2.3 2 0 0 2 2 2 0 Potyviridae polyprotein Chromo PF00385.19 GAM23210.1 - 8.9e-14 50.9 3.7 7.3e-11 41.5 0.6 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 GAM23210.1 - 8.5e-06 25.5 0.3 0.00069 19.3 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Neisseria_TspB PF05616.8 GAM23210.1 - 0.048 12.0 5.7 0.078 11.3 3.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein WGG PF10273.4 GAM23211.1 - 5.9e-24 83.9 0.1 1.2e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 GAM23211.1 - 0.0049 16.8 0.7 0.0049 16.8 0.5 2.3 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Methyltransf_23 PF13489.1 GAM23212.1 - 5.9e-20 71.6 0.0 1e-19 70.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23212.1 - 2e-16 60.2 0.1 4.2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23212.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23212.1 - 2.3e-13 50.4 0.0 4.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23212.1 - 1.5e-11 44.8 0.0 2.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM23212.1 - 1.2e-09 37.6 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 GAM23212.1 - 4.5e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23212.1 - 4.8e-06 26.8 0.1 8.8e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM23212.1 - 1.3e-05 24.4 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAM23212.1 - 2.9e-05 23.5 0.0 7.8e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 GAM23212.1 - 0.00017 20.8 0.0 0.00023 20.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 GAM23212.1 - 0.00098 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAM23212.1 - 0.0011 17.7 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 GAM23212.1 - 0.0039 16.3 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.6 GAM23212.1 - 0.009 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.7 GAM23212.1 - 0.031 13.6 0.1 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Coatomer_E PF04733.9 GAM23212.1 - 0.087 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Tetraspannin PF00335.15 GAM23213.1 - 0.054 12.7 1.2 7.1 5.8 0.1 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF202 PF02656.10 GAM23213.1 - 0.066 13.4 0.6 0.52 10.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF3754 PF12576.3 GAM23213.1 - 0.073 12.7 0.3 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF1201 PF06716.6 GAM23213.1 - 0.67 9.8 4.6 1.7 8.5 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Pkinase_Tyr PF07714.12 GAM23214.1 - 6.9e-61 205.5 0.1 1.8e-60 204.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23214.1 - 2.4e-57 194.0 0.0 8.3e-57 192.2 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.14 GAM23214.1 - 2.5e-19 69.4 5.4 2.5e-19 69.4 3.8 2.6 3 0 0 3 3 3 1 Regulator of G protein signaling domain APH PF01636.18 GAM23214.1 - 0.00018 21.3 1.2 0.00099 18.9 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family GpcrRhopsn4 PF10192.4 GAM23214.1 - 0.005 16.0 0.1 0.009 15.2 0.1 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain RIO1 PF01163.17 GAM23214.1 - 0.0073 15.6 0.1 0.0073 15.6 0.1 3.2 4 0 0 4 4 4 2 RIO1 family Macoilin PF09726.4 GAM23214.1 - 5.3 5.2 39.7 0.018 13.3 18.6 2.1 2 0 0 2 2 2 0 Transmembrane protein Ank_2 PF12796.2 GAM23215.1 - 8.2e-14 51.7 0.3 5.1e-07 29.9 0.0 3.6 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM23215.1 - 2.9e-07 30.7 0.4 6e-05 23.4 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM23215.1 - 9.7e-07 28.8 2.2 0.0026 17.9 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23215.1 - 0.00012 21.9 0.8 1.4 9.3 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeat Ank PF00023.25 GAM23215.1 - 0.00058 19.5 0.7 0.39 10.6 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeat NIF PF03031.13 GAM23216.1 - 8.8e-17 61.2 0.6 8.8e-17 61.2 0.4 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 GAM23216.1 - 9.1e-13 48.1 0.0 3.9e-12 46.1 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM23216.1 - 4.5e-10 39.2 0.1 1e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain bZIP_1 PF00170.16 GAM23217.1 - 2e-06 27.6 3.9 2e-06 27.6 2.7 3.7 5 0 0 5 5 5 1 bZIP transcription factor bZIP_2 PF07716.10 GAM23217.1 - 3e-05 23.7 6.7 3e-05 23.7 4.6 5.0 5 0 0 5 5 5 1 Basic region leucine zipper SAE2 PF08573.5 GAM23218.1 - 1e-11 45.3 3.3 1.8e-07 31.7 0.1 4.6 3 2 1 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus ZF-HD_dimer PF04770.7 GAM23218.1 - 0.032 14.2 0.1 0.074 13.1 0.1 1.6 1 0 0 1 1 1 0 ZF-HD protein dimerisation region SWIB PF02201.13 GAM23218.1 - 0.045 13.4 0.9 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 SWIB/MDM2 domain Fez1 PF06818.10 GAM23218.1 - 6.6 6.6 18.1 0.046 13.7 4.0 2.5 1 1 1 2 2 2 0 Fez1 DWNN PF08783.6 GAM23219.1 - 1.7e-11 43.9 1.6 4.5e-11 42.5 0.1 2.4 2 1 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 GAM23219.1 - 9.4e-08 31.4 7.1 2.5e-07 30.0 4.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 GAM23219.1 - 0.00038 20.2 2.5 0.00038 20.2 1.7 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4 PF00097.20 GAM23219.1 - 0.15 11.7 10.6 0.4 10.3 7.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Eapp_C PF10238.4 GAM23219.1 - 3.8 7.4 14.3 2.4 8.0 5.2 3.3 2 1 1 3 3 3 0 E2F-associated phosphoprotein zf-CCHC_3 PF13917.1 GAM23219.1 - 6.7 6.5 9.0 0.11 12.2 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle FYDLN_acid PF09538.5 GAM23219.1 - 9 6.9 11.7 9.6 6.8 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) AD PF09793.4 GAM23220.1 - 2.9e-24 84.6 0.0 4.7e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain DUF842 PF05811.8 GAM23220.1 - 0.051 13.0 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) SM-ATX PF14438.1 GAM23220.1 - 0.19 11.6 1.8 0.21 11.5 0.3 2.0 2 1 0 2 2 2 0 Ataxin 2 SM domain Cyt-b5 PF00173.23 GAM23221.1 - 4.3e-23 80.9 0.0 9.3e-23 79.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zip PF02535.17 GAM23221.1 - 0.0081 15.2 5.1 0.011 14.8 3.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2946 PF11162.3 GAM23221.1 - 0.12 12.5 0.3 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Tudor-knot PF11717.3 GAM23221.1 - 0.16 11.6 1.2 6.2 6.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF3591 PF12157.3 GAM23222.1 - 2.1e-117 392.3 0.0 2.1e-117 392.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 GAM23222.1 - 1.7e-15 56.7 0.5 7.8e-15 54.5 0.3 2.2 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.6 GAM23222.1 - 0.00052 20.1 1.2 0.00052 20.1 0.8 2.5 2 0 0 2 2 2 1 TATA box-binding protein binding AAA_2 PF07724.9 GAM23223.1 - 9e-58 194.9 0.0 3.2e-53 180.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 GAM23223.1 - 2.6e-27 95.5 0.0 9.5e-15 54.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 GAM23223.1 - 7e-22 77.1 5.5 8.3e-13 48.0 0.2 2.9 2 0 0 2 2 2 2 Clp amino terminal domain ClpB_D2-small PF10431.4 GAM23223.1 - 5.2e-21 74.3 0.1 5.2e-21 74.3 0.1 3.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 GAM23223.1 - 4.5e-19 68.5 0.1 3.5e-12 46.2 0.0 3.5 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM23223.1 - 6.7e-15 55.5 5.0 3.3e-06 27.2 0.0 4.7 4 3 2 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.21 GAM23223.1 - 4.7e-10 39.2 0.0 2e-06 27.3 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 GAM23223.1 - 4.8e-10 39.6 0.3 0.0029 17.7 0.0 4.7 3 2 1 4 4 3 2 AAA domain AAA_17 PF13207.1 GAM23223.1 - 1.5e-09 38.6 1.5 0.0037 18.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 GAM23223.1 - 1.7e-08 34.8 0.1 0.0065 16.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 GAM23223.1 - 1.8e-08 34.0 0.0 0.002 17.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 GAM23223.1 - 3.8e-08 33.2 0.0 0.012 15.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 GAM23223.1 - 9.6e-06 24.8 1.3 0.02 13.9 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 GAM23223.1 - 3.4e-05 23.0 0.0 0.0064 15.6 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.7 GAM23223.1 - 5.8e-05 22.8 0.0 0.19 11.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 GAM23223.1 - 7.7e-05 22.8 0.0 0.98 9.6 0.0 3.4 3 0 0 3 3 3 2 RNA helicase Arch_ATPase PF01637.13 GAM23223.1 - 0.00011 21.9 7.6 0.082 12.5 0.5 4.5 3 2 0 3 3 2 1 Archaeal ATPase AAA_25 PF13481.1 GAM23223.1 - 0.00014 21.3 0.3 0.51 9.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_19 PF13245.1 GAM23223.1 - 0.00016 21.3 0.0 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_3 PF07726.6 GAM23223.1 - 0.00036 20.1 0.0 0.3 10.7 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAM23223.1 - 0.00044 20.2 1.1 1.6 8.6 0.0 3.6 3 2 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAM23223.1 - 0.0021 17.9 0.0 0.73 9.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM23223.1 - 0.0025 16.9 0.0 1.8 7.6 0.0 3.2 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.1 GAM23223.1 - 0.0027 17.4 0.0 0.017 14.7 0.0 2.4 2 1 0 2 2 1 1 DNA polymerase III, delta subunit T2SE PF00437.15 GAM23223.1 - 0.0036 16.2 0.1 0.046 12.6 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.22 GAM23223.1 - 0.0042 17.3 0.5 1.4 9.1 0.0 3.9 4 1 0 4 4 3 1 ABC transporter DUF87 PF01935.12 GAM23223.1 - 0.0057 16.5 6.2 0.27 11.0 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function DUF87 DUF258 PF03193.11 GAM23223.1 - 0.0059 15.8 0.0 3 6.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 GAM23223.1 - 0.0079 15.8 0.0 13 5.4 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 GAM23223.1 - 0.012 15.3 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAM23223.1 - 0.02 14.3 1.0 2 7.7 0.1 3.6 2 2 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 GAM23223.1 - 0.026 14.0 0.0 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 GAM23223.1 - 0.026 14.0 0.0 4.1 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 GAM23223.1 - 0.027 14.2 0.0 3.2 7.5 0.0 3.3 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 GAM23223.1 - 0.036 13.5 0.2 9.3 5.6 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 GAM23223.1 - 0.35 9.2 8.5 0.77 8.1 5.9 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM23223.1 - 1.1 9.5 20.2 0.16 12.3 0.1 4.1 3 2 0 3 3 2 0 AAA domain RhoGAP PF00620.22 GAM23225.1 - 4.4e-35 120.5 0.1 1.8e-34 118.5 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain RhoGEF PF00621.15 GAM23225.1 - 5.1e-34 117.7 2.1 5.1e-34 117.7 1.4 2.3 4 0 0 4 4 4 1 RhoGEF domain PH PF00169.24 GAM23225.1 - 2.4e-06 27.6 0.5 5.7e-06 26.4 0.3 1.7 1 0 0 1 1 1 1 PH domain IQ PF00612.22 GAM23225.1 - 0.00097 18.5 0.2 0.0025 17.3 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Hrs_helical PF12210.3 GAM23225.1 - 0.044 14.0 0.5 33 4.8 0.0 3.4 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4145 PF13643.1 GAM23226.1 - 0.056 13.3 0.2 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Pex14_N PF04695.8 GAM23226.1 - 0.068 13.2 9.7 0.14 12.2 2.7 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Uds1 PF15456.1 GAM23226.1 - 7.4 6.5 16.8 12 5.9 4.7 2.8 2 1 0 2 2 2 0 Up-regulated During Septation FtsJ PF01728.14 GAM23227.1 - 1.2e-28 100.3 0.0 1.9e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1183 PF06682.7 GAM23228.1 - 0.0055 16.3 1.2 0.0074 15.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Profilin PF00235.14 GAM23229.1 - 4.3e-09 36.5 0.0 5.2e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Profilin RE_CfrBI PF09516.5 GAM23229.1 - 0.012 14.5 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease Na_K-ATPase PF00287.13 GAM23229.1 - 0.039 12.7 0.1 0.045 12.5 0.1 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF1565 PF07602.6 GAM23229.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) Med15 PF09606.5 GAM23230.1 - 1.8 6.6 67.7 1.5 6.8 15.3 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 GAM23230.1 - 2.6 6.1 54.1 2.8 6.0 10.6 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Cro PF09048.5 GAM23231.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Cro Coiled PF05710.7 GAM23231.1 - 3.8 8.0 10.0 6.1 7.3 7.0 1.4 1 1 0 1 1 1 0 Coiled coil Xpo1 PF08389.7 GAM23232.1 - 6.3e-36 123.5 1.0 6.3e-36 123.5 0.7 4.2 5 0 0 5 5 5 1 Exportin 1-like protein Epimerase PF01370.16 GAM23233.1 - 4.8e-24 85.0 0.0 1.7e-23 83.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM23233.1 - 4.5e-20 71.6 0.0 1.5e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 GAM23233.1 - 6.5e-14 51.3 0.0 1.6e-06 27.0 0.0 2.9 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM23233.1 - 1.7e-09 37.0 0.0 1.3e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM23233.1 - 1.8e-05 23.7 0.0 4.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM23233.1 - 1.9e-05 24.7 0.0 0.036 14.0 0.0 3.3 3 1 1 4 4 4 2 NADH(P)-binding NmrA PF05368.8 GAM23233.1 - 0.0077 15.5 0.0 0.018 14.2 0.0 1.7 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 GAM23233.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM23233.1 - 0.025 14.4 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FKBP_C PF00254.23 GAM23234.1 - 1e-34 118.4 0.1 1.2e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase G-alpha PF00503.15 GAM23235.1 - 7.4e-108 360.6 6.3 8.8e-108 360.4 4.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM23235.1 - 9.1e-13 47.8 0.5 1.6e-08 33.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 GAM23235.1 - 0.0015 19.0 0.1 3.1 8.3 0.0 3.1 3 1 0 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 GAM23235.1 - 0.035 13.5 0.6 0.36 10.2 0.4 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM23235.1 - 0.035 14.0 0.0 1 9.3 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 GAM23235.1 - 0.052 12.7 0.9 2.3 7.4 0.1 2.8 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 GAM23235.1 - 0.27 11.1 2.5 0.57 10.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain Nucleoporin2 PF04096.9 GAM23236.1 - 4.1e-42 143.3 0.0 8.8e-42 142.2 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase ApoL PF05461.6 GAM23236.1 - 0.00081 18.7 0.6 0.0014 17.9 0.4 1.3 1 0 0 1 1 1 1 Apolipoprotein L TIG PF01833.19 GAM23238.1 - 8.7e-87 285.2 125.6 2.8e-14 52.8 2.7 14.3 14 1 0 14 14 14 11 IPT/TIG domain TIG PF01833.19 GAM23239.1 - 6e-69 228.0 128.0 2.3e-10 40.2 0.7 19.0 20 2 0 20 20 20 13 IPT/TIG domain DNase_II PF03265.10 GAM23239.1 - 7.4e-35 120.4 0.3 2.4e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 Deoxyribonuclease II Cna_B PF05738.8 GAM23239.1 - 2.8e-08 33.3 8.0 4.4e-08 32.7 0.4 3.8 3 0 0 3 3 3 1 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM23239.1 - 6.9e-07 29.2 23.2 5e-06 26.4 2.0 5.4 6 0 0 6 6 6 2 Carboxypeptidase regulatory-like domain Nsp1_C PF05064.8 GAM23239.1 - 1.6 8.4 0.1 3.1 7.4 0.1 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region PLRV_ORF5 PF01690.12 GAM23239.1 - 2.3 7.2 1.9 4.4 6.3 1.3 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Acyl_CoA_thio PF02551.10 GAM23240.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA thioesterase Lipase_3 PF01764.20 GAM23241.1 - 1.9e-33 115.0 0.0 2.6e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM23241.1 - 2.2e-07 30.5 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.17 GAM23241.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 GAM23241.1 - 0.014 15.2 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM23241.1 - 0.015 15.0 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Complex1_51K PF01512.12 GAM23241.1 - 0.035 13.8 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit PGAP1 PF07819.8 GAM23241.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 PGAP1-like protein NT-C2 PF10358.4 GAM23242.1 - 8.4e-10 38.3 0.0 2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 GAM23242.1 - 1.3e-07 31.4 5.5 2.8e-07 30.3 3.8 1.6 1 0 0 1 1 1 1 DIL domain Pirin PF02678.11 GAM23243.1 - 1.5e-37 127.7 0.5 3.7e-37 126.4 0.3 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 GAM23243.1 - 6.2e-31 106.5 0.1 1.6e-29 102.0 0.0 2.4 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 GAM23243.1 - 0.0038 16.6 1.1 0.73 9.3 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Ribosomal_S25 PF03297.10 GAM23244.1 - 7.1e-37 125.6 1.1 8e-37 125.4 0.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Rrf2 PF02082.15 GAM23244.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TATR PF03430.8 GAM23244.1 - 0.21 10.2 1.2 0.24 9.9 0.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator WD40 PF00400.27 GAM23245.1 - 1.5e-17 62.7 17.5 1.7e-06 27.6 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 GAM23245.1 - 0.00031 20.4 4.0 0.2 11.3 0.1 4.0 3 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A SnoaL_2 PF12680.2 GAM23245.1 - 0.012 15.9 0.1 0.037 14.4 0.1 1.7 1 0 0 1 1 1 0 SnoaL-like domain Dynamitin PF04912.9 GAM23246.1 - 2e-104 349.5 14.1 2.2e-104 349.3 9.8 1.0 1 0 0 1 1 1 1 Dynamitin Pox_A_type_inc PF04508.7 GAM23246.1 - 1.7 8.6 7.6 22 5.1 0.1 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 GAM23246.1 - 3 6.9 12.2 33 3.4 6.9 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cohesin_load PF10345.4 GAM23247.1 - 4.4e-07 28.5 29.3 5e-05 21.7 9.9 2.6 2 1 0 2 2 2 2 Cohesin loading factor FNIP PF05725.7 GAM23248.1 - 3.3e-14 52.5 10.6 2.7e-05 24.0 0.2 6.8 4 3 1 6 6 6 5 FNIP Repeat LRR_8 PF13855.1 GAM23248.1 - 3.3 7.5 8.8 11 5.9 0.2 3.7 3 1 0 3 3 3 0 Leucine rich repeat TLD PF07534.11 GAM23250.1 - 6.7e-34 116.8 1.2 1.2e-33 116.0 0.8 1.4 1 0 0 1 1 1 1 TLD FH2 PF02181.18 GAM23251.1 - 3.1e-84 283.0 13.4 5.8e-84 282.0 9.3 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 GAM23251.1 - 5.7e-16 58.5 0.8 5.7e-16 58.5 0.6 3.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAM23251.1 - 6.5e-11 41.9 0.7 6.5e-11 41.9 0.5 2.7 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FHA PF00498.21 GAM23251.1 - 1.8e-09 37.5 0.0 2e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 FHA domain FTP PF07504.8 GAM23252.1 - 0.052 13.0 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DUF737 PF05300.6 GAM23252.1 - 0.68 9.8 6.5 1.3 8.9 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Syntaxin PF00804.20 GAM23252.1 - 8.5 6.6 14.6 24 5.1 7.6 2.7 2 1 1 3 3 3 0 Syntaxin Bud13 PF09736.4 GAM23253.1 - 1.5e-40 138.7 16.1 1.5e-40 138.7 11.2 3.8 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex PI3Ka PF00613.15 GAM23254.1 - 6.2e-55 185.2 4.0 1.2e-54 184.2 2.7 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM23254.1 - 2.9e-49 167.6 0.0 2.2e-48 164.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM23254.1 - 6.9e-32 110.1 0.0 1.6e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HEAT_2 PF13646.1 GAM23254.1 - 0.083 13.1 0.5 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats CBM49 PF09478.5 GAM23255.1 - 4.8e-11 42.5 0.3 6.7e-11 42.1 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF4354 PF14263.1 GAM23255.1 - 0.038 13.6 0.1 0.051 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) CBM49 PF09478.5 GAM23256.1 - 2.1e-11 43.7 0.4 2.9e-11 43.2 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 NAD_binding_5 PF07994.7 GAM23257.1 - 9.5e-109 363.4 0.1 1.1e-108 363.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 GAM23257.1 - 9.1e-48 160.7 0.3 1.7e-47 159.8 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DNA_pol_A_exo1 PF01612.15 GAM23258.1 - 2e-38 131.6 0.4 2.6e-38 131.2 0.3 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 GAM23258.1 - 2.9e-08 33.2 0.0 1.6e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 HRDC domain Pox_A22 PF04848.8 GAM23259.1 - 0.07 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A22 protein Aminotran_1_2 PF00155.16 GAM23260.1 - 6.8e-40 137.1 0.0 9.4e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM23260.1 - 0.0068 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2888 PF11135.3 GAM23260.1 - 0.072 12.7 0.0 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2888) Leo1 PF04004.8 GAM23261.1 - 8.1e-42 142.8 0.3 8.1e-42 142.8 0.2 4.2 3 1 2 5 5 5 1 Leo1-like protein MIP-T3 PF10243.4 GAM23261.1 - 1.6 7.1 69.1 0.2 10.0 30.0 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF1191 PF06697.7 GAM23262.1 - 0.0097 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 GAM23262.1 - 0.016 15.5 0.4 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.6 GAM23262.1 - 0.16 11.6 0.4 0.43 10.3 0.1 1.8 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 FAM163 PF15069.1 GAM23262.1 - 0.17 12.4 1.6 0.44 11.1 0.9 1.8 1 1 1 2 2 2 0 FAM163 family Adeno_E3_CR2 PF02439.10 GAM23262.1 - 0.27 10.8 0.9 0.49 9.9 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mucin PF01456.12 GAM23262.1 - 3.2 7.5 7.7 8.3 6.1 5.3 1.8 1 1 0 1 1 1 0 Mucin-like glycoprotein RCR PF12273.3 GAM23262.1 - 3.2 8.3 8.7 0.62 10.6 2.3 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Peptidase_C1 PF00112.18 GAM23263.1 - 1.3e-47 162.4 1.0 1.3e-47 162.4 0.7 2.0 1 1 0 2 2 2 1 Papain family cysteine protease CAP PF00188.21 GAM23263.1 - 5e-09 36.6 7.2 5e-09 36.6 5.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DEAD PF00270.24 GAM23265.1 - 1.4e-27 96.2 2.5 5.1e-27 94.4 0.7 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM23265.1 - 8.5e-24 83.2 0.2 2.5e-23 81.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM23265.1 - 0.0015 18.4 0.0 0.0038 17.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2999 PF11212.3 GAM23265.1 - 0.038 14.0 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) AAA_22 PF13401.1 GAM23265.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 GAM23265.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Guanylate_cyc PF00211.15 GAM23266.1 - 1.3e-83 278.9 1.0 3.3e-45 153.7 0.1 3.1 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.9 GAM23266.1 - 0.0047 16.1 5.8 0.05 12.8 0.1 3.0 3 0 0 3 3 3 2 Heme NO binding associated Ank_2 PF12796.2 GAM23267.1 - 3.7e-13 49.6 0.0 7.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM23267.1 - 6.8e-11 41.4 0.1 4.1e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAM23267.1 - 1.8e-08 34.6 0.0 2.8e-05 24.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM23267.1 - 2.9e-08 33.6 0.0 6.4e-06 26.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23267.1 - 7.9e-06 25.6 0.3 0.0026 17.8 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat DNA_ligase_A_N PF04675.9 GAM23268.1 - 0.03 14.1 0.1 0.098 12.4 0.0 1.8 2 0 0 2 2 2 0 DNA ligase N terminus Peptidase_M1 PF01433.15 GAM23269.1 - 1.7e-20 73.5 5.3 2.4e-18 66.4 0.2 2.6 1 1 0 2 2 2 2 Peptidase family M1 MaoC_dehydratas PF01575.14 GAM23270.1 - 5.4e-23 80.6 0.0 6.3e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 GAM23270.1 - 2.7e-06 27.2 0.0 4.2e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 GAM23270.1 - 0.078 13.1 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 Thioesterase superfamily Myb_DNA-binding PF00249.26 GAM23271.1 - 2.2e-10 40.4 0.0 4.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM23271.1 - 2e-05 24.5 0.1 2e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SPACA7 PF15307.1 GAM23271.1 - 5.2 7.2 13.5 0.27 11.3 4.4 2.6 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Y_phosphatase2 PF03162.8 GAM23272.1 - 2e-55 186.6 0.0 2.3e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAM23272.1 - 0.0013 18.9 0.0 0.01 16.0 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family tRNA_int_endo PF01974.12 GAM23273.1 - 2.4e-22 78.5 0.0 5e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 GAM23273.1 - 5.3e-10 38.6 1.5 3.7e-07 29.5 0.2 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain AATF-Che1 PF13339.1 GAM23273.1 - 0.045 13.9 1.5 0.072 13.2 0.0 2.0 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor E1-E2_ATPase PF00122.15 GAM23274.1 - 2.6e-59 200.0 1.8 2.6e-59 200.0 1.3 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 GAM23274.1 - 2e-25 90.5 0.0 4.5e-25 89.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM23274.1 - 6.5e-14 52.5 0.0 1.7e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM23274.1 - 2.9e-12 45.8 0.0 6e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM23274.1 - 0.00013 21.6 0.1 0.0012 18.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM23274.1 - 0.015 15.2 0.0 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit S4 PF01479.20 GAM23274.1 - 0.13 11.6 0.1 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 S4 domain OHA PF14418.1 GAM23275.1 - 0.0059 16.0 0.1 0.056 12.9 0.0 2.4 1 1 1 2 2 2 1 OST-HTH Associated domain SSFA2_C PF14723.1 GAM23275.1 - 0.035 13.8 0.6 0.035 13.8 0.4 1.8 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus UPF0086 PF01868.11 GAM23276.1 - 1.4e-23 82.3 0.0 4.8e-23 80.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Methyltransf_15 PF09445.5 GAM23277.1 - 2.9e-38 131.0 0.5 4.5e-38 130.3 0.1 1.5 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 GAM23277.1 - 1.2e-09 38.1 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 GAM23277.1 - 2.4e-09 37.0 0.0 4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 GAM23277.1 - 5.7e-06 26.8 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM23277.1 - 2.7e-05 23.6 0.0 7.2e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 GAM23277.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAM23277.1 - 0.0071 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Nop14 PF04147.7 GAM23277.1 - 0.0082 14.1 14.7 0.011 13.7 10.2 1.1 1 0 0 1 1 1 1 Nop14-like family PrmA PF06325.8 GAM23277.1 - 0.082 12.0 0.1 0.082 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Merozoite_SPAM PF07133.6 GAM23277.1 - 0.14 12.0 15.0 0.22 11.3 10.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.9 GAM23277.1 - 0.85 7.5 13.7 1.1 7.1 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 GAM23277.1 - 5.2 5.4 19.7 7.1 4.9 13.7 1.2 1 0 0 1 1 1 0 Daxx Family S-antigen PF05756.6 GAM23277.1 - 7 6.7 7.8 31 4.6 3.6 2.5 2 0 0 2 2 2 0 S-antigen protein hDGE_amylase PF14701.1 GAM23279.1 - 6.7e-157 522.7 0.2 9e-157 522.2 0.2 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 GAM23279.1 - 8.8e-106 353.7 0.0 1.6e-105 352.8 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 GAM23279.1 - 1.1e-68 231.3 0.0 1.6e-68 230.7 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 GAM23279.1 - 6.5e-06 25.8 0.1 1.5e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Leu_zip PF15294.1 GAM23281.1 - 0.12 11.5 31.2 0.93 8.5 11.5 2.5 1 1 1 2 2 2 0 Leucine zipper KID PF02524.9 GAM23281.1 - 0.14 12.3 2.8 3.4 8.1 0.1 3.2 2 0 0 2 2 2 0 KID repeat HSBP1 PF06825.7 GAM23281.1 - 0.22 11.1 6.6 3 7.5 0.2 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF2849 PF11011.3 GAM23281.1 - 0.3 11.3 0.2 0.3 11.3 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2849) CpeS PF09367.5 GAM23281.1 - 9.6 6.0 12.0 8.5 6.2 0.3 2.1 1 1 1 2 2 2 0 CpeS-like protein Dscam_C PF12355.3 GAM23283.1 - 0.14 12.4 0.7 0.21 11.8 0.5 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Dicty_spore_N PF04562.7 GAM23284.1 - 3.5e-14 53.1 11.4 3.5e-14 53.1 7.9 3.7 2 1 2 4 4 4 1 Dictyostelium spore coat protein, N terminus CytochromB561_N PF09786.4 GAM23285.1 - 1.8e-11 43.2 0.5 1.8e-11 43.2 0.4 3.3 2 1 1 3 3 3 1 Cytochrome B561, N terminal ACBP PF00887.14 GAM23286.1 - 6.1e-18 64.2 0.0 1.2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.25 GAM23286.1 - 6.3e-16 57.2 1.0 4.9e-08 32.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 GAM23286.1 - 6.7e-16 57.9 0.5 7.4e-10 38.7 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM23286.1 - 3.7e-15 55.9 0.9 1.8e-09 37.8 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM23286.1 - 3.4e-14 52.9 0.1 5.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM23286.1 - 1.5e-07 30.9 0.1 0.0005 20.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat DDHD PF02862.12 GAM23286.1 - 0.067 12.9 2.7 0.086 12.6 1.9 1.2 1 0 0 1 1 1 0 DDHD domain SSP160 PF06933.6 GAM23286.1 - 0.22 9.4 2.8 0.26 9.1 1.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 GAM23286.1 - 0.48 8.1 4.2 0.58 7.8 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PH_10 PF15411.1 GAM23287.1 - 0.12 12.5 0.6 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1996 PF09362.5 GAM23288.1 - 8.6e-33 113.9 0.0 1.7e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PA14_2 PF10528.4 GAM23288.1 - 0.03 14.2 0.4 0.073 13.0 0.3 1.6 1 0 0 1 1 1 0 GLEYA domain MGC-24 PF05283.6 GAM23288.1 - 0.34 10.6 17.5 0.47 10.2 11.6 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Mucin PF01456.12 GAM23288.1 - 2.3 7.9 22.8 4.1 7.1 15.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PH_10 PF15411.1 GAM23289.1 - 0.074 13.2 0.3 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain CR6_interact PF10147.4 GAM23290.1 - 0.025 13.8 0.3 0.04 13.2 0.2 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF2344 PF10105.4 GAM23290.1 - 0.079 12.4 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) CBM49 PF09478.5 GAM23292.1 - 5.3e-17 61.6 0.0 7.4e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Ank_2 PF12796.2 GAM23293.1 - 4.6e-64 212.7 42.2 1.2e-10 41.5 0.1 6.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM23293.1 - 3.2e-37 126.2 14.9 3.6e-07 30.5 0.0 8.8 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM23293.1 - 5.1e-35 118.6 23.3 0.0026 17.9 0.0 13.2 1 1 14 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23293.1 - 8.3e-29 96.7 14.1 0.06 13.6 0.0 13.1 8 3 6 14 14 14 8 Ankyrin repeat Ank PF00023.25 GAM23293.1 - 1.1e-23 81.7 18.4 0.1 12.4 0.0 13.6 10 3 4 14 14 14 8 Ankyrin repeat Lipoprot_C PF08794.5 GAM23293.1 - 0.041 13.7 0.6 22 4.8 0.0 4.4 1 1 4 5 5 5 0 Lipoprotein GNA1870 C terminal like Kunitz_BPTI PF00014.18 GAM23293.1 - 0.048 13.8 3.8 16 5.7 0.0 5.2 3 2 4 7 7 7 0 Kunitz/Bovine pancreatic trypsin inhibitor domain zf-4CXXC_R1 PF10497.4 GAM23293.1 - 0.099 12.7 0.2 38 4.4 0.0 4.5 3 2 3 6 6 6 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Spo0A_C PF08769.6 GAM23293.1 - 0.16 11.8 0.7 4.6 7.1 0.0 3.4 2 2 2 4 4 4 0 Sporulation initiation factor Spo0A C terminal TLD PF07534.11 GAM23294.1 - 3e-39 134.1 3.1 1.2e-38 132.2 2.1 2.1 1 0 0 1 1 1 1 TLD LysM PF01476.15 GAM23294.1 - 7.2e-07 28.9 0.0 7e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 LysM domain Neur_chan_memb PF02932.11 GAM23294.1 - 8 6.2 20.4 5.7 6.7 8.1 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4419 PF14388.1 GAM23295.1 - 4.6e-83 278.8 0.2 1.2e-81 274.2 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) GrpE PF01025.14 GAM23295.1 - 0.05 13.1 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 GrpE DUF3149 PF11346.3 GAM23295.1 - 0.11 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF932 PF06067.6 GAM23295.1 - 0.12 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF4419 PF14388.1 GAM23296.1 - 1.1e-96 323.5 0.1 1.3e-96 323.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GrpE PF01025.14 GAM23296.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 GrpE DUF2009 PF09418.5 GAM23297.1 - 2.6e-196 652.8 0.1 3.5e-196 652.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 GAM23297.1 - 5.3e-06 26.2 4.8 9.5e-06 25.4 3.3 1.4 1 0 0 1 1 1 1 B-box zinc finger Laminin_EGF PF00053.19 GAM23297.1 - 0.24 11.3 11.8 0.47 10.4 8.2 1.4 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) IBR PF01485.16 GAM23297.1 - 1.8 8.4 10.1 14 5.6 7.0 2.2 1 1 0 1 1 1 0 IBR domain DUF3439 PF11921.3 GAM23298.1 - 1.6 8.4 22.7 0.36 10.5 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mgr1 PF08602.5 GAM23298.1 - 1.8 7.5 9.7 11 4.9 4.7 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit HPS3_Mid PF14762.1 GAM23299.1 - 1.3e-35 122.7 1.7 2.2e-35 121.9 1.2 1.3 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.1 GAM23299.1 - 5.8e-13 48.7 0.0 5.7e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 Hermansky-Pudlak syndrome 3 Sec1 PF00995.18 GAM23300.1 - 3.7e-71 240.4 3.0 5.2e-71 239.9 2.1 1.2 1 0 0 1 1 1 1 Sec1 family HSP20 PF00011.16 GAM23301.1 - 7.5e-23 80.3 0.6 1e-22 79.9 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 GAM23301.1 - 0.062 12.9 0.2 0.16 11.6 0.0 1.7 1 1 1 2 2 2 0 GvpH YhzD PF14120.1 GAM23301.1 - 0.086 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 YhzD-like protein Ank_2 PF12796.2 GAM23302.1 - 7.1e-17 61.5 2.6 5.3e-06 26.6 0.8 5.5 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM23302.1 - 2.3e-06 27.3 9.8 5.4 7.5 0.0 8.0 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.1 GAM23302.1 - 0.0014 19.1 6.9 0.36 11.3 0.0 5.5 5 2 1 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM23302.1 - 1.2 9.1 13.4 22 5.0 0.1 6.5 7 0 0 7 7 7 0 Ankyrin repeat Ribosomal_L13 PF00572.13 GAM23303.1 - 1.1e-25 90.1 0.1 3.1e-25 88.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 UPF0220 PF05255.6 GAM23304.1 - 1.8e-42 144.4 1.9 1.9e-42 144.3 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3112 PF11309.3 GAM23304.1 - 0.0011 18.8 1.1 0.0014 18.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) Lysine_decarbox PF03641.9 GAM23305.1 - 7.2e-43 145.5 0.0 9e-43 145.2 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase Amino_oxidase PF01593.19 GAM23306.1 - 1.4e-38 133.1 0.2 2.2e-26 92.9 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM23306.1 - 9.3e-09 35.1 0.1 2.4e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM23306.1 - 0.002 17.2 0.3 0.0032 16.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 GAM23306.1 - 0.0054 16.8 0.2 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM23306.1 - 0.0083 16.5 0.1 0.017 15.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 GAM23306.1 - 0.069 12.7 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3603 PF12227.3 GAM23306.1 - 0.46 9.5 2.3 0.63 9.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) TPR_19 PF14559.1 GAM23307.1 - 1.1e-19 70.5 11.9 7.3e-06 26.2 0.5 3.5 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM23307.1 - 4.7e-16 57.8 1.4 5.8e-06 26.4 0.2 4.6 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM23307.1 - 9.2e-13 47.3 4.6 0.00023 21.1 0.2 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM23307.1 - 1.2e-10 41.7 7.3 6.7e-05 23.4 0.0 3.7 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM23307.1 - 1e-09 38.1 13.3 0.00042 20.1 0.5 4.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM23307.1 - 3.1e-08 33.1 9.9 8.5e-06 25.3 2.1 3.1 1 1 3 4 4 4 3 TPR repeat TPR_2 PF07719.12 GAM23307.1 - 1.9e-07 30.4 9.0 0.11 12.4 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM23307.1 - 3.3e-06 26.4 3.2 2 8.3 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM23307.1 - 1.6e-05 24.3 13.6 0.64 9.9 0.1 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM23307.1 - 4e-05 23.6 2.2 0.00018 21.5 1.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM23307.1 - 8.4e-05 21.7 3.2 0.073 12.1 0.4 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM23307.1 - 0.0022 17.5 5.5 0.49 10.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat FAT PF02259.18 GAM23307.1 - 0.004 16.1 1.4 0.31 9.9 0.0 2.5 1 1 1 2 2 2 1 FAT domain TPR_6 PF13174.1 GAM23307.1 - 0.01 16.2 7.7 6.2 7.5 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 GAM23307.1 - 0.013 15.4 0.1 1.3 9.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat ChAPs PF09295.5 GAM23307.1 - 0.013 14.2 0.1 0.077 11.7 0.1 1.9 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Mad3_BUB1_I PF08311.7 GAM23307.1 - 0.032 13.9 0.9 0.29 10.9 0.5 2.5 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 Apc3 PF12895.2 GAM23307.1 - 0.033 14.3 4.0 0.074 13.1 2.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Med17 PF10156.4 GAM23307.1 - 0.077 11.2 2.1 0.1 10.8 1.4 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex TPR_9 PF13371.1 GAM23307.1 - 0.12 12.2 1.7 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 GAM23307.1 - 0.15 11.9 5.6 1 9.3 2.0 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 GAM23307.1 - 3.1 8.5 8.4 1.5 9.5 0.1 3.4 4 0 0 4 4 2 0 Sel1 repeat DUF3560 PF12083.3 GAM23307.1 - 5.2 7.1 11.1 5.5 7.0 1.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) DEAD PF00270.24 GAM23308.1 - 4.1e-35 120.7 0.0 2.1e-34 118.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM23308.1 - 5.2e-21 74.2 0.0 1.7e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM23308.1 - 2.8e-11 43.5 0.5 6.8e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 GAM23308.1 - 0.0087 16.2 1.5 0.13 12.4 0.3 3.1 2 1 0 2 2 2 1 AAA domain SNF2_N PF00176.18 GAM23308.1 - 0.014 14.2 0.0 0.014 14.2 0.0 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain Kelch_6 PF13964.1 GAM23309.1 - 8.4e-05 22.5 2.3 0.039 14.1 0.2 3.4 3 0 0 3 3 3 1 Kelch motif DUF1664 PF07889.7 GAM23309.1 - 0.00015 21.5 3.1 0.0002 21.1 1.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Kelch_2 PF07646.10 GAM23309.1 - 0.004 16.8 1.0 0.018 14.8 0.1 2.5 2 0 0 2 2 2 1 Kelch motif GLE1 PF07817.8 GAM23309.1 - 0.11 11.4 4.6 0.15 10.9 3.2 1.2 1 0 0 1 1 1 0 GLE1-like protein Kelch_4 PF13418.1 GAM23309.1 - 0.11 12.3 3.4 2.1 8.1 0.3 3.4 2 1 1 3 3 3 0 Galactose oxidase, central domain LAGLIDADG_WhiA PF14527.1 GAM23309.1 - 0.16 11.8 1.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain DUF725 PF05267.7 GAM23309.1 - 0.32 10.9 3.7 0.35 10.7 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF725) LOH1CR12 PF10158.4 GAM23309.1 - 0.35 10.6 4.6 0.19 11.4 1.1 2.1 2 0 0 2 2 2 0 Tumour suppressor protein DUF29 PF01724.11 GAM23309.1 - 0.71 9.7 5.6 3.1 7.6 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF29 Snapin_Pallidin PF14712.1 GAM23309.1 - 2.4 8.5 6.0 1.2 9.5 1.6 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Kelch_2 PF07646.10 GAM23310.1 - 0.00078 19.1 0.3 0.18 11.5 0.1 3.6 3 0 0 3 3 3 1 Kelch motif DUF1664 PF07889.7 GAM23310.1 - 0.0035 17.1 3.1 0.0065 16.2 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Kelch_4 PF13418.1 GAM23310.1 - 0.0063 16.2 3.8 6.8 6.5 0.2 4.5 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM23310.1 - 0.012 15.8 9.5 0.069 13.3 0.3 5.1 5 1 1 6 6 6 0 Kelch motif Snapin_Pallidin PF14712.1 GAM23310.1 - 0.08 13.2 4.5 0.17 12.2 3.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Kelch_1 PF01344.20 GAM23310.1 - 0.13 11.8 1.2 2.3 7.8 0.0 3.3 3 0 0 3 3 3 0 Kelch motif MitMem_reg PF13012.1 GAM23310.1 - 0.19 11.8 3.3 0.46 10.5 2.3 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function GLE1 PF07817.8 GAM23310.1 - 0.78 8.6 4.5 1.3 7.9 3.1 1.3 1 0 0 1 1 1 0 GLE1-like protein Kelch_6 PF13964.1 GAM23311.1 - 0.014 15.5 5.0 45 4.4 0.0 5.4 5 1 1 6 6 6 0 Kelch motif DUF948 PF06103.6 GAM23311.1 - 0.17 11.7 4.1 0.75 9.7 2.9 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 GAM23311.1 - 0.24 11.2 11.9 0.025 14.3 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 GAM23311.1 - 0.48 10.7 8.5 0.12 12.6 3.2 1.9 2 0 0 2 2 2 0 Snapin/Pallidin GLE1 PF07817.8 GAM23311.1 - 0.66 8.8 6.3 1 8.2 4.4 1.2 1 0 0 1 1 1 0 GLE1-like protein Kelch_1 PF01344.20 GAM23311.1 - 6.5 6.3 7.7 80 2.8 0.2 4.5 5 0 0 5 5 5 0 Kelch motif Peptidase_C14 PF00656.17 GAM23312.1 - 0.00077 19.2 0.0 0.002 17.8 0.0 1.7 2 0 0 2 2 2 1 Caspase domain KAP_NTPase PF07693.9 GAM23314.1 - 0.058 12.3 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Remorin_C PF03763.8 GAM23317.1 - 0.0029 17.1 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Remorin, C-terminal region APG17 PF04108.7 GAM23317.1 - 0.0092 14.8 0.6 0.015 14.1 0.4 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 Vps51 PF08700.6 GAM23317.1 - 0.063 13.1 0.3 0.24 11.2 0.1 2.1 1 1 1 2 2 2 0 Vps51/Vps67 Orbi_VP5 PF00901.12 GAM23317.1 - 0.068 11.3 0.2 0.093 10.9 0.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 ApoLp-III PF07464.6 GAM23317.1 - 0.14 12.1 0.8 0.23 11.4 0.5 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_11 PF13414.1 GAM23318.1 - 4.8e-38 128.6 6.1 1.2e-15 56.9 0.0 5.4 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM23318.1 - 7.3e-32 107.6 9.9 1.4e-05 24.4 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 GAM23318.1 - 8.9e-28 93.9 4.6 0.00012 21.7 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM23318.1 - 5.3e-14 52.4 0.0 2e-05 25.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM23318.1 - 9.8e-12 44.6 1.2 0.045 13.6 0.1 5.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM23318.1 - 3.1e-11 42.8 0.2 0.012 16.1 0.0 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM23318.1 - 8.9e-10 38.2 0.0 0.00036 20.3 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM23318.1 - 5.4e-09 35.5 8.1 0.00039 20.3 0.0 7.7 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM23318.1 - 2.9e-08 32.9 6.3 0.13 12.1 0.0 6.3 5 1 1 6 6 6 2 Tetratricopeptide repeat DUF357 PF04010.8 GAM23318.1 - 0.02 14.6 0.6 6.2 6.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF357) DUF4557 PF15101.1 GAM23318.1 - 0.38 10.5 19.9 0.42 10.4 12.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DXP_synthase_N PF13292.1 GAM23318.1 - 1.5 7.7 10.3 0.69 8.7 5.2 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF4175 PF13779.1 GAM23318.1 - 5.7 4.5 37.6 9 3.8 26.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4220 PF13968.1 GAM23318.1 - 9.4 5.2 10.4 19 4.2 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) TPR_19 PF14559.1 GAM23319.1 - 0.00011 22.4 6.4 2 8.8 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM23319.1 - 0.0025 18.3 1.2 23 5.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM23319.1 - 0.0075 16.1 5.3 0.027 14.3 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat WD40 PF00400.27 GAM23320.1 - 1.7e-24 84.7 13.4 2.7e-08 33.3 1.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM23320.1 - 0.026 12.8 0.1 1.5 7.0 0.0 2.9 2 1 1 3 3 3 0 Cytochrome D1 heme domain Ric8 PF10165.4 GAM23321.1 - 2.2e-22 79.5 0.0 1.5e-21 76.8 0.0 2.2 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Bot1p PF12298.3 GAM23322.1 - 2.1e-07 31.0 0.0 3.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DGCR6 PF07324.6 GAM23323.1 - 3.3e-08 33.2 4.3 3.3e-08 33.2 3.0 1.9 2 0 0 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein SR-25 PF10500.4 GAM23323.1 - 5.9e-06 25.9 6.0 5.9e-06 25.9 4.2 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein FLO_LFY PF01698.11 GAM23323.1 - 2.1 7.0 11.2 6.4 5.5 7.8 1.8 1 0 0 1 1 1 0 Floricaula / Leafy protein Pkinase_Tyr PF07714.12 GAM23324.1 - 1.4e-56 191.4 0.0 2.3e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23324.1 - 2.9e-56 190.5 0.1 1.1e-55 188.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 GAM23324.1 - 0.028 13.3 0.0 0.061 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 GAM23324.1 - 0.042 13.5 0.4 0.082 12.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Suf PF05843.9 GAM23324.1 - 1.1 8.9 8.1 1.8 8.2 5.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dicty_REP PF05086.7 GAM23324.1 - 2.8 5.5 5.4 3.9 5.1 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein His_Phos_1 PF00300.17 GAM23325.1 - 1e-18 67.9 0.0 1.4e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RVT_1 PF00078.22 GAM23326.1 - 1.8e-37 128.7 0.0 4.7e-37 127.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 GAM23326.1 - 1.1e-06 28.2 0.3 2.2e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 GAM23326.1 - 0.00037 20.5 1.0 0.00067 19.6 0.4 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SHMT PF00464.14 GAM23327.1 - 0.0029 16.0 0.1 0.004 15.5 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF4504 PF14953.1 GAM23328.1 - 2.8e-18 66.1 2.7 3.6e-18 65.8 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) DUF3472 PF11958.3 GAM23329.1 - 2.3e-24 86.7 0.8 2.3e-24 86.7 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3472) Ricin_B_lectin PF00652.17 GAM23329.1 - 6.7e-17 61.6 12.9 1.1e-16 60.9 8.9 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain GPI-anchored PF10342.4 GAM23329.1 - 0.017 15.5 1.1 0.017 15.5 0.8 3.2 2 1 1 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RicinB_lectin_2 PF14200.1 GAM23329.1 - 0.07 13.5 7.5 0.44 10.9 0.6 3.4 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like DUF3430 PF11912.3 GAM23330.1 - 8.9e-21 74.6 13.2 1e-20 74.4 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Kelch_6 PF13964.1 GAM23331.1 - 5e-09 35.9 3.3 0.00089 19.3 0.0 4.2 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM23331.1 - 0.0051 16.5 1.3 0.38 10.5 0.0 4.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM23331.1 - 0.01 15.5 0.0 0.067 12.9 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 GAM23331.1 - 0.03 13.8 0.3 4.8 6.8 0.0 3.4 3 0 0 3 3 3 0 Kelch motif PQ-loop PF04193.9 GAM23332.1 - 2e-24 84.9 13.8 3.3e-13 48.9 1.8 2.6 2 0 0 2 2 2 2 PQ loop repeat HEAT_EZ PF13513.1 GAM23333.1 - 1.5e-35 120.7 5.5 3e-14 52.9 0.0 11.0 11 0 0 11 11 11 4 HEAT-like repeat HEAT PF02985.17 GAM23333.1 - 2e-32 108.3 17.1 0.00049 19.9 0.0 11.9 12 0 0 12 12 11 6 HEAT repeat HEAT_2 PF13646.1 GAM23333.1 - 8e-30 102.9 0.0 3e-08 33.8 0.0 7.2 5 3 4 9 9 8 8 HEAT repeats Cnd1 PF12717.2 GAM23333.1 - 2.9e-14 53.2 4.5 1.2e-06 28.5 0.0 5.0 3 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAM23333.1 - 1.7e-13 49.8 3.6 0.038 13.8 0.0 7.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 GAM23333.1 - 9.3e-11 41.9 0.2 0.077 13.3 0.0 7.1 5 2 4 9 9 9 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 GAM23333.1 - 6.2e-10 38.0 6.1 4.1e-05 22.0 0.6 4.0 3 2 0 3 3 3 2 Adaptin N terminal region IBN_N PF03810.14 GAM23333.1 - 6.6e-09 35.5 4.3 2.4e-08 33.7 0.1 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain UME PF08064.8 GAM23333.1 - 0.00011 22.1 3.6 0.89 9.5 0.0 4.6 4 1 1 5 5 5 2 UME (NUC010) domain Xpo1 PF08389.7 GAM23333.1 - 0.0038 17.1 4.7 0.26 11.2 0.0 4.3 4 1 1 5 5 5 1 Exportin 1-like protein MMS19_C PF12460.3 GAM23333.1 - 0.0042 15.8 2.2 0.0042 15.8 1.6 3.8 3 3 0 5 5 5 1 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 GAM23333.1 - 0.016 15.6 0.0 0.55 10.8 0.0 3.7 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat BK_channel_a PF03493.13 GAM23334.1 - 8.9e-22 76.9 0.8 3.2e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 GAM23334.1 - 5.7e-14 51.5 4.2 1.2e-13 50.5 2.9 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.26 GAM23334.1 - 2.7e-06 26.7 14.5 0.00097 18.4 10.1 2.6 1 1 0 1 1 1 1 Ion transport protein TrkA_N PF02254.13 GAM23334.1 - 1.9e-05 24.6 0.0 0.036 14.0 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain DUF3592 PF12158.3 GAM23335.1 - 0.0054 16.5 6.0 0.044 13.5 4.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3592) Dicty_REP PF05086.7 GAM23336.1 - 0.0098 13.7 5.5 0.011 13.5 3.8 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAM23336.1 - 0.45 10.2 10.6 0.83 9.4 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM23336.1 - 1.4 8.6 12.9 2.3 7.9 8.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.20 GAM23337.1 - 2.6e-43 148.0 0.0 2.6e-43 148.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23337.1 - 1.9e-19 69.7 0.0 1.9e-19 69.7 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase RabGAP-TBC PF00566.13 GAM23338.1 - 3.7e-42 144.2 0.3 3.7e-42 144.2 0.2 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PAP1 PF08601.5 GAM23338.1 - 0.023 14.4 3.9 0.045 13.4 2.7 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4337 PF14235.1 GAM23338.1 - 0.29 10.9 3.5 0.43 10.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Vfa1 PF08432.5 GAM23338.1 - 0.33 10.9 8.8 0.66 9.9 6.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2951 PF11166.3 GAM23338.1 - 1.2 9.0 8.1 3.7 7.4 5.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) WD40 PF00400.27 GAM23339.1 - 9.2e-45 148.9 9.0 7.9e-09 35.0 0.4 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM23339.1 - 1e-08 33.8 0.9 0.22 9.5 0.2 5.0 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Hira PF07569.6 GAM23339.1 - 0.0054 15.9 0.2 0.91 8.6 0.0 3.7 3 1 0 4 4 4 1 TUP1-like enhancer of split Nucleoporin_N PF08801.6 GAM23339.1 - 0.0061 15.3 1.2 0.45 9.1 0.6 3.4 1 1 2 3 3 3 1 Nup133 N terminal like EF-hand_1 PF00036.27 GAM23340.1 - 5e-26 87.9 8.0 6.6e-06 25.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 GAM23340.1 - 1.9e-23 80.1 1.9 5.8e-06 25.7 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 GAM23340.1 - 1.3e-22 79.6 7.2 8e-11 41.9 0.1 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM23340.1 - 3.2e-19 67.3 9.8 9.6e-06 24.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 GAM23340.1 - 3.9e-13 48.7 2.2 0.0083 15.7 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM23340.1 - 2e-06 27.8 0.3 0.1 12.5 0.0 3.1 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM23340.1 - 0.0018 17.9 4.1 7.9 6.2 0.0 4.1 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.1 GAM23340.1 - 0.0031 17.3 0.1 0.081 12.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.2 GAM23340.1 - 0.004 16.8 4.4 0.034 13.8 0.1 3.2 2 2 2 4 4 4 1 Cytoskeletal-regulatory complex EF hand DUF4335 PF14233.1 GAM23340.1 - 0.037 13.5 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) EGF_2 PF07974.8 GAM23341.1 - 0.0054 16.8 14.1 0.011 15.9 9.8 1.5 1 0 0 1 1 1 1 EGF-like domain RasGEF PF00617.14 GAM23342.1 - 1.2e-69 233.8 0.4 2.4e-69 232.8 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM23342.1 - 3.5e-26 91.3 0.5 3.5e-26 91.3 0.4 3.8 4 0 0 4 4 4 1 RasGEF N-terminal motif DUF1202 PF06717.6 GAM23342.1 - 0.013 14.7 1.3 0.013 14.7 0.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1202) FNIP_M PF14637.1 GAM23343.1 - 8e-61 205.5 0.4 2.6e-60 203.9 0.1 2.0 2 0 0 2 2 2 1 Folliculin-interacting protein middle domain FNIP_C PF14638.1 GAM23343.1 - 9e-20 70.8 0.0 2.8e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.1 GAM23343.1 - 1.9e-15 57.4 6.6 1.9e-15 57.4 4.6 4.4 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus DUF4484 PF14831.1 GAM23343.1 - 0.089 12.8 1.5 3.2 7.8 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Suf PF05843.9 GAM23343.1 - 0.18 11.4 18.3 0.42 10.2 3.4 2.7 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Rifin_STEVOR PF02009.11 GAM23344.1 - 0.01 15.4 0.3 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family EGF_2 PF07974.8 GAM23344.1 - 0.053 13.7 14.6 0.12 12.6 10.1 1.6 1 0 0 1 1 1 0 EGF-like domain HATPase_c PF02518.21 GAM23344.1 - 0.086 12.5 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EGF_2 PF07974.8 GAM23345.1 - 1.4 9.1 15.3 2.9 8.1 10.6 1.6 1 0 0 1 1 1 0 EGF-like domain Glyco_transf_10 PF00852.14 GAM23346.1 - 9.4e-56 188.8 5.8 1.1e-55 188.6 4.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Ribosomal_L34e PF01199.13 GAM23347.1 - 2.1e-38 130.4 5.8 2.1e-38 130.4 4.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e zinc-ribbons_6 PF07191.7 GAM23347.1 - 0.011 15.4 0.3 0.65 9.8 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 GAM23347.1 - 0.15 11.9 1.1 0.47 10.4 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain ZZ PF00569.12 GAM23347.1 - 0.16 11.5 1.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, ZZ type SKIP_SNW PF02731.10 GAM23348.1 - 1.3e-59 200.1 6.4 1.3e-59 200.1 4.4 2.9 3 0 0 3 3 3 1 SKIP/SNW domain EF-hand_1 PF00036.27 GAM23349.1 - 1.9e-22 76.8 9.2 6.9e-08 31.2 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 GAM23349.1 - 1.1e-19 70.3 2.2 9.4e-10 38.4 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM23349.1 - 6.4e-18 62.9 6.5 1.4e-07 30.8 0.1 5.6 4 2 2 6 6 6 3 EF-hand domain EF-hand_9 PF14658.1 GAM23349.1 - 4.2e-10 39.3 0.1 4.1e-07 29.7 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM23349.1 - 6.4e-10 37.9 6.2 3.2e-06 26.2 0.1 4.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 GAM23349.1 - 6.5e-09 35.2 9.5 0.026 14.1 0.1 5.0 2 1 3 5 5 5 4 EF-hand domain pair EF-hand_4 PF12763.2 GAM23349.1 - 0.0042 16.7 2.0 0.39 10.4 0.1 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 GAM23349.1 - 0.031 13.8 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PBS_linker_poly PF00427.16 GAM23349.1 - 0.064 12.9 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide Aminotran_5 PF00266.14 GAM23350.1 - 3.4e-46 157.6 0.0 3.9e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Allene_ox_cyc PF06351.6 GAM23350.1 - 0.075 12.4 0.2 0.19 11.1 0.1 1.6 1 1 0 1 1 1 0 Allene oxide cyclase SWIRM PF04433.12 GAM23352.1 - 9.5e-27 92.9 0.1 2.5e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 GAM23352.1 - 2.2e-06 27.5 0.0 3.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM23352.1 - 7.8e-05 22.6 0.2 0.00019 21.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L20 PF00453.13 GAM23352.1 - 0.077 12.9 1.0 0.18 11.7 0.7 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 Mucin PF01456.12 GAM23352.1 - 0.17 11.6 39.5 0.028 14.1 7.6 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF3439 PF11921.3 GAM23352.1 - 5.7 6.7 34.7 0.079 12.7 7.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) FtsJ PF01728.14 GAM23355.1 - 6.9e-48 163.0 0.0 8.5e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 GAM23355.1 - 0.00015 21.3 0.0 0.0013 18.3 0.0 2.1 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAM23355.1 - 0.0069 16.4 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23355.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23355.1 - 0.032 13.3 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAM23355.1 - 0.067 12.7 0.0 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 GAM23355.1 - 0.068 12.5 0.0 0.45 9.8 0.0 2.1 2 1 0 2 2 2 0 NOL1/NOP2/sun family LMBR1 PF04791.11 GAM23356.1 - 3.4e-59 200.6 38.1 1.2e-40 139.4 12.9 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein GP41 PF00517.12 GAM23356.1 - 0.011 15.2 0.2 0.032 13.7 0.1 1.8 1 0 0 1 1 1 0 Retroviral envelope protein SIT PF15330.1 GAM23356.1 - 0.017 15.2 0.7 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT RRM_6 PF14259.1 GAM23358.1 - 1e-06 28.6 0.1 1.6e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM23358.1 - 2.8e-06 26.8 0.3 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_ligase PF09414.5 GAM23359.1 - 2e-16 60.3 0.0 4e-16 59.3 0.0 1.5 1 1 0 1 1 1 1 RNA ligase GlcNAc PF11397.3 GAM23360.1 - 7.2e-86 288.3 0.0 2e-85 286.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF4289 PF14121.1 GAM23361.1 - 0.11 10.9 2.8 0.14 10.5 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) Uds1 PF15456.1 GAM23361.1 - 0.12 12.3 4.8 0.29 11.1 3.4 1.7 1 1 0 1 1 1 0 Up-regulated During Septation TINF2_N PF14973.1 GAM23361.1 - 0.22 11.6 0.3 0.22 11.6 0.2 1.8 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus RhoGEF PF00621.15 GAM23362.1 - 9.1e-46 155.9 4.1 9.1e-46 155.9 2.9 2.4 3 0 0 3 3 3 1 RhoGEF domain PX PF00787.19 GAM23362.1 - 1.7e-19 69.6 1.1 5.6e-19 68.0 0.4 2.2 2 0 0 2 2 2 1 PX domain DUF748 PF05359.6 GAM23363.1 - 0.015 15.3 2.2 1.5 8.8 0.2 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF748) Lectin_legB PF00139.14 GAM23364.1 - 9.4e-24 84.0 0.1 3.7e-23 82.1 0.0 1.8 2 0 0 2 2 2 1 Legume lectin domain DUF3439 PF11921.3 GAM23364.1 - 0.003 17.3 3.3 0.0069 16.1 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) UDP-g_GGTase PF06427.6 GAM23364.1 - 0.088 12.0 0.9 0.31 10.3 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase SSP160 PF06933.6 GAM23364.1 - 0.79 7.6 5.0 1.1 7.1 3.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Methyltransf_31 PF13847.1 GAM23365.1 - 1.1e-12 47.8 0.2 1.8e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23365.1 - 1.3e-10 41.8 0.0 3.3e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 GAM23365.1 - 2.6e-10 39.8 0.1 3.5e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 GAM23365.1 - 8.5e-10 38.2 0.1 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 GAM23365.1 - 6e-09 35.9 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23365.1 - 7e-08 32.8 0.0 2.2e-07 31.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAM23365.1 - 1.6e-07 30.3 0.1 2.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 GAM23365.1 - 4.3e-06 26.5 0.0 9.1e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM23365.1 - 1.3e-05 24.6 0.1 2.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM23365.1 - 0.00039 20.7 0.0 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM23365.1 - 0.00069 19.1 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 GAM23365.1 - 0.00074 19.9 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM23365.1 - 0.0035 16.4 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 GAM23365.1 - 0.0083 16.1 0.0 0.02 14.8 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 GAM23365.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 GAM23365.1 - 0.029 13.9 0.1 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 GAM23365.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UBX PF00789.15 GAM23366.1 - 9.3e-15 54.4 0.0 1.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.18 GAM23366.1 - 0.0018 17.6 1.2 0.016 14.5 0.0 3.1 4 0 0 4 4 4 1 Ubiquitin family Ubiquitin_2 PF14560.1 GAM23366.1 - 0.0048 17.1 0.0 0.21 11.8 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-like domain Thioredoxin_7 PF13899.1 GAM23366.1 - 0.0092 15.9 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like GCD14 PF08704.5 GAM23366.1 - 2.5 7.5 13.5 0.052 13.0 2.5 2.1 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit MRP-L46 PF11788.3 GAM23366.1 - 2.8 8.6 9.1 2.2 8.9 0.1 2.4 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 IPPT PF01715.12 GAM23367.1 - 2.4e-52 177.4 6.0 4.3e-30 104.5 2.0 2.6 2 0 0 2 2 2 2 IPP transferase zf-C2H2_jaz PF12171.3 GAM23367.1 - 1.6e-07 31.2 1.7 3.5e-07 30.1 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.1 GAM23367.1 - 3.1e-07 30.7 2.2 0.00053 20.3 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM23367.1 - 3.2e-06 27.9 0.1 3.2e-06 27.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain zf-met PF12874.2 GAM23367.1 - 9.4e-06 25.6 1.5 2.1e-05 24.5 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type IPT PF01745.11 GAM23367.1 - 1.6e-05 24.1 0.0 3.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase Hpr_kinase_C PF07475.7 GAM23367.1 - 0.0011 18.2 0.2 0.0011 18.2 0.1 2.1 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain RNA_helicase PF00910.17 GAM23367.1 - 0.0033 17.5 0.1 0.032 14.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SKI PF01202.17 GAM23367.1 - 0.0044 16.9 0.1 1.4 8.7 0.0 3.0 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 GAM23367.1 - 0.0073 16.1 4.7 0.024 14.5 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 GAM23367.1 - 0.01 15.9 0.1 0.04 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain HARP PF07443.8 GAM23367.1 - 0.055 12.8 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) AAA PF00004.24 GAM23367.1 - 0.073 13.2 0.8 0.37 11.0 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3439 PF11921.3 GAM23367.1 - 1.5 8.5 12.7 3.3 7.4 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ribosomal_S11 PF00411.14 GAM23368.1 - 4.5e-28 97.6 0.1 6e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Phage_glycop_gL PF11108.3 GAM23369.1 - 0.082 12.8 0.3 0.089 12.7 0.2 1.3 1 1 0 1 1 1 0 Viral glycoprotein L Glyco_hydro_18 PF00704.23 GAM23370.1 - 0.0049 16.3 0.1 0.0071 15.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 7tm_3 PF00003.17 GAM23371.1 - 3.4e-34 118.2 27.5 3.4e-34 118.2 19.1 1.5 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 GAM23371.1 - 1.6e-12 46.8 0.4 2.3e-12 46.2 0.3 1.1 1 0 0 1 1 1 1 Basic membrane protein DUF4460 PF14687.1 GAM23372.1 - 2.3e-06 27.3 0.3 2.3e-06 27.3 0.2 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4460) DUF2547 PF10818.3 GAM23372.1 - 0.35 11.5 12.8 0.21 12.2 3.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) RR_TM4-6 PF06459.7 GAM23372.1 - 9.3 6.0 18.8 2.7 7.7 1.2 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 GAM23375.1 - 1.2e-17 63.0 1.4 7.6e-06 25.6 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM23375.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain Pkinase PF00069.20 GAM23376.1 - 1.8e-50 171.5 0.0 3.8e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23376.1 - 1.8e-37 128.8 0.0 4e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.22 GAM23376.1 - 7.8e-31 106.7 0.2 2.2e-30 105.2 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain Kinase-like PF14531.1 GAM23376.1 - 0.0005 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ABC_tran_2 PF12848.2 GAM23376.1 - 0.0043 16.8 4.0 0.014 15.2 2.8 1.8 1 0 0 1 1 1 1 ABC transporter PH PF00169.24 GAM23376.1 - 0.0079 16.3 0.9 0.066 13.4 0.6 2.5 1 1 0 1 1 1 1 PH domain DUF972 PF06156.8 GAM23376.1 - 9.1 6.6 8.3 4 7.8 2.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RRM_1 PF00076.17 GAM23377.1 - 1.9e-16 59.4 0.1 2.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM23377.1 - 2.1e-12 46.7 0.0 3.2e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM23377.1 - 4.4e-08 32.8 0.0 6.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM23377.1 - 0.0075 15.9 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 Myb_DNA-binding PF00249.26 GAM23378.1 - 2.1e-29 101.3 13.1 4.2e-13 49.1 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM23378.1 - 1.7e-27 95.3 7.3 2.2e-15 56.4 0.3 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 GAM23378.1 - 0.66 9.9 6.9 16 5.4 0.0 4.5 3 2 2 5 5 5 0 Myb/SANT-like DNA-binding domain FNIP PF05725.7 GAM23379.1 - 3e-61 203.1 12.6 1.5e-16 60.0 0.1 7.4 7 1 0 7 7 7 6 FNIP Repeat Chitin_bind_3 PF03067.10 GAM23380.1 - 2.9e-39 135.2 0.4 2.9e-39 135.2 0.3 2.2 2 0 0 2 2 2 1 Chitin binding domain GMC_oxred_N PF00732.14 GAM23381.1 - 8.1e-45 153.2 0.1 1.4e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM23381.1 - 5.6e-20 72.1 0.4 1.7e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 GAM23381.1 - 2.3e-09 36.6 0.4 0.00018 20.5 0.1 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM23381.1 - 2.3e-06 26.7 0.1 5.4e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 GAM23381.1 - 0.0002 21.3 0.1 0.00051 20.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM23381.1 - 0.00021 20.4 0.8 0.00033 19.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM23381.1 - 0.00029 20.0 0.3 0.00059 18.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 GAM23381.1 - 0.0026 17.6 0.0 0.0068 16.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM23381.1 - 0.021 13.2 1.7 0.046 12.1 1.2 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 GAM23381.1 - 0.022 13.7 0.1 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 GAM23381.1 - 0.04 13.3 1.0 0.078 12.4 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Abhydrolase_3 PF07859.8 GAM23381.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGM_PMM_II PF02879.11 GAM23381.1 - 0.17 12.2 0.0 8.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF508 PF04370.7 GAM23381.1 - 0.36 10.4 3.9 0.2 11.2 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Mito_carr PF00153.22 GAM23382.1 - 5.1e-67 221.6 5.3 1.6e-21 75.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 GAM23382.1 - 0.015 15.4 0.1 0.06 13.4 0.0 1.9 2 0 0 2 2 2 0 Corticotropin-releasing factor family AIG2 PF06094.7 GAM23383.1 - 0.12 12.8 1.1 0.42 11.1 0.0 2.2 2 0 0 2 2 2 0 AIG2-like family Cyt-b5 PF00173.23 GAM23384.1 - 3.4e-23 81.2 0.3 4.5e-23 80.8 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Aph-1 PF06105.7 GAM23385.1 - 5.2e-69 232.1 13.9 6.2e-69 231.8 9.6 1.0 1 0 0 1 1 1 1 Aph-1 protein Wzy_C PF04932.10 GAM23385.1 - 0.0073 16.1 2.1 0.0073 16.1 1.4 2.0 2 0 0 2 2 2 1 O-Antigen ligase FYVE PF01363.16 GAM23386.1 - 1.2e-19 69.9 8.8 2.4e-19 69.0 6.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.18 GAM23386.1 - 1.1e-13 50.4 3.0 0.014 15.1 0.0 5.6 6 0 0 6 6 6 4 Armadillo/beta-catenin-like repeat FYVE_2 PF02318.11 GAM23386.1 - 0.0084 15.9 7.1 0.023 14.6 4.9 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger DUF383 PF04063.9 GAM23386.1 - 0.0094 15.5 2.8 0.46 9.9 0.5 3.1 1 1 0 2 2 2 1 Domain of unknown function (DUF383) Mig-14 PF07395.6 GAM23386.1 - 0.054 12.4 0.1 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Mig-14 zf-RING_5 PF14634.1 GAM23386.1 - 9.7 6.0 14.8 29 4.4 10.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain GTP_EFTU PF00009.22 GAM23387.1 - 5.4e-58 195.5 0.1 7.6e-58 195.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM23387.1 - 1.5e-33 114.8 0.2 6.1e-33 112.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM23387.1 - 1.7e-17 63.2 0.5 4.3e-17 61.9 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM23387.1 - 5.6e-05 23.0 0.1 0.00019 21.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAM23387.1 - 5.7e-05 22.6 0.2 0.00017 21.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.7 GAM23387.1 - 0.0043 16.2 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM23387.1 - 0.04 14.3 0.3 0.37 11.3 0.2 2.3 1 1 0 1 1 1 0 Miro-like protein tRNA-synt_1b PF00579.20 GAM23388.1 - 1.1e-21 77.2 0.0 4.5e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HsdM_N PF12161.3 GAM23388.1 - 0.15 12.4 3.7 6.1 7.2 0.2 2.8 2 1 0 2 2 2 0 HsdM N-terminal domain Dus PF01207.12 GAM23390.1 - 1.9e-53 181.2 0.0 3.1e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 GAM23390.1 - 4e-09 35.9 8.7 5.3e-07 29.1 0.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Red1 PF07964.6 GAM23390.1 - 1.3 7.0 18.8 0.0031 15.7 6.1 1.5 2 0 0 2 2 2 0 Rec10 / Red1 zf-CCCH_2 PF14608.1 GAM23390.1 - 2.3 8.3 6.1 4.9 7.3 1.1 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type adh_short PF00106.20 GAM23391.1 - 0.00035 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase FNIP PF05725.7 GAM23392.1 - 3.8e-43 145.1 16.1 7.8e-14 51.3 0.7 5.6 3 2 2 5 5 5 5 FNIP Repeat He_PIG_assoc PF10632.4 GAM23392.1 - 0.053 12.8 2.6 12 5.3 0.0 3.5 3 0 0 3 3 3 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase VRR_NUC PF08774.6 GAM23393.1 - 1.4e-17 63.5 0.0 9.1e-17 60.9 0.0 2.2 2 0 0 2 2 2 1 VRR-NUC domain Thioredoxin PF00085.15 GAM23394.1 - 1.1e-32 111.7 0.1 1.1e-15 57.1 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 GAM23394.1 - 8.7e-11 41.9 0.2 2e-07 31.0 0.0 3.9 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAM23394.1 - 1.8e-08 34.5 4.4 0.00064 19.8 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAM23394.1 - 4.3e-06 26.6 0.1 0.043 13.8 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 GAM23394.1 - 8.6e-05 22.5 1.1 0.64 10.1 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Redoxin PF08534.5 GAM23394.1 - 0.00032 20.2 0.1 0.014 14.9 0.0 2.5 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 GAM23394.1 - 0.002 17.8 0.1 0.27 10.9 0.0 2.8 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 GAM23394.1 - 0.052 13.1 4.5 0.055 13.0 0.0 2.9 2 1 0 2 2 2 0 Thioredoxin Sdh5 PF03937.11 GAM23394.1 - 0.057 13.1 2.4 0.086 12.5 0.0 2.6 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase Glutaredoxin PF00462.19 GAM23394.1 - 0.33 10.9 1.8 28 4.7 0.6 3.0 2 1 0 2 2 2 0 Glutaredoxin UPF0172 PF03665.8 GAM23394.1 - 0.36 10.2 5.3 3.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Endonuc_Holl PF10107.4 GAM23394.1 - 2.1 8.0 7.9 4.6 6.9 5.5 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Glyco_hydro_47 PF01532.15 GAM23395.1 - 5.9e-129 430.6 1.4 7e-129 430.3 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4419 PF14388.1 GAM23396.1 - 6.6e-84 281.6 0.3 9.3e-84 281.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GrpE PF01025.14 GAM23396.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 GrpE SLA_LP_auto_ag PF05889.8 GAM23397.1 - 4.1e-128 427.1 0.0 4.9e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 GAM23397.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase zf-RING_2 PF13639.1 GAM23398.1 - 6.8e-15 54.6 6.7 1e-14 54.0 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM23398.1 - 1.8e-07 31.1 7.1 3.6e-07 30.1 4.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 GAM23398.1 - 2.3e-07 30.3 3.4 3.5e-07 29.7 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM23398.1 - 9.6e-07 28.7 8.0 1.5e-06 28.0 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM23398.1 - 3.2e-06 26.7 8.7 5.6e-06 25.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM23398.1 - 7e-05 22.5 1.0 0.0001 22.0 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 GAM23398.1 - 0.00086 18.9 5.9 0.0014 18.3 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM23398.1 - 0.018 14.7 4.4 0.045 13.4 3.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 GAM23398.1 - 0.03 14.3 3.9 0.072 13.1 2.7 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 GAM23398.1 - 0.037 13.6 5.1 0.074 12.6 3.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H_2 PF13832.1 GAM23398.1 - 0.037 14.0 1.2 0.062 13.3 0.8 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain UPF0547 PF10571.4 GAM23398.1 - 0.053 13.2 0.2 0.053 13.2 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF1272 PF06906.6 GAM23398.1 - 0.26 11.1 3.2 0.46 10.3 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FANCL_C PF11793.3 GAM23398.1 - 0.28 11.1 8.4 4.1 7.4 5.8 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 GAM23398.1 - 0.5 10.2 5.8 1.4 8.8 4.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 GAM23398.1 - 1.1 8.7 6.9 6.3 6.3 4.9 2.1 1 1 1 2 2 2 0 P-11 zinc finger zf-RING-like PF08746.6 GAM23398.1 - 3.7 7.6 6.2 6.9 6.7 4.3 1.5 1 1 0 1 1 1 0 RING-like domain Hist_deacetyl PF00850.14 GAM23399.1 - 1.5e-70 237.9 2.8 2.1e-70 237.5 0.1 2.2 2 0 0 2 2 2 1 Histone deacetylase domain His_kinase PF06580.8 GAM23399.1 - 6.4 6.7 8.4 0.59 10.0 0.5 3.0 3 0 0 3 3 3 0 Histidine kinase EamA PF00892.15 GAM23400.1 - 2.5e-08 33.9 31.9 3e-06 27.2 0.8 3.9 3 1 1 4 4 4 2 EamA-like transporter family DUF2077 PF09850.4 GAM23400.1 - 0.03 13.7 0.1 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Phostensin_N PF13916.1 GAM23400.1 - 0.032 14.2 1.0 0.057 13.3 0.2 1.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Ank_2 PF12796.2 GAM23401.1 - 3.9e-42 142.4 25.8 2.3e-09 37.4 0.9 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM23401.1 - 8.4e-35 118.5 20.5 5.9e-05 23.4 0.1 11.2 8 5 4 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23401.1 - 5.4e-32 106.6 29.0 0.051 13.8 0.0 14.9 8 2 8 16 16 16 9 Ankyrin repeat Ank_5 PF13857.1 GAM23401.1 - 4.2e-30 103.0 29.6 0.00011 22.2 0.1 15.0 2 2 14 16 16 16 9 Ankyrin repeats (many copies) Ank PF00023.25 GAM23401.1 - 5.8e-24 82.6 29.1 0.27 11.1 0.0 14.8 13 2 2 15 15 15 10 Ankyrin repeat Vps23_core PF09454.5 GAM23401.1 - 0.045 13.3 0.0 1.8e+02 1.8 0.0 5.6 8 0 0 8 8 8 0 Vps23 core domain Peripla_BP_5 PF13433.1 GAM23401.1 - 0.064 12.0 0.1 57 2.2 0.0 4.2 2 2 2 5 5 5 0 Periplasmic binding protein domain FaeA PF04703.7 GAM23401.1 - 0.11 12.6 0.6 4.8 7.4 0.0 3.7 4 0 0 4 4 4 0 FaeA-like protein DUF1843 PF08898.5 GAM23401.1 - 0.11 12.5 0.0 33 4.6 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) tRNA_synt_1c_R1 PF04558.10 GAM23401.1 - 0.47 9.9 2.7 75 2.7 0.0 4.8 6 0 0 6 6 6 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Synaptobrevin PF00957.16 GAM23402.1 - 4.5e-26 90.2 6.0 6.2e-26 89.8 4.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAM23402.1 - 2.6e-17 62.1 0.0 4.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF4448 PF14610.1 GAM23402.1 - 0.011 15.1 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3753 PF12575.3 GAM23402.1 - 1.2 9.0 6.7 4.3 7.1 2.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Sigma_reg_N PF13800.1 GAM23402.1 - 2.8 8.0 6.3 4.1 7.4 2.0 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2392 PF10288.4 GAM23403.1 - 0.0015 18.8 1.7 0.0015 18.8 1.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) PPO1_KFDV PF12143.3 GAM23403.1 - 0.021 14.7 0.5 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF_B2219) Sipho_Gp157 PF05565.6 GAM23403.1 - 0.075 12.6 6.9 0.13 11.8 4.8 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 Peptidase_S30 PF01577.11 GAM23403.1 - 3.4 7.0 7.9 0.99 8.7 3.3 1.7 2 0 0 2 2 2 0 Potyvirus P1 protease Mlf1IP PF10248.4 GAM23403.1 - 6.7 6.2 11.5 10 5.6 2.6 2.5 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Transposase_22 PF02994.9 GAM23403.1 - 7.3 4.9 13.6 0.2 10.1 3.5 2.2 2 0 0 2 2 2 0 L1 transposable element ParA PF10609.4 GAM23404.1 - 1.9e-36 123.7 1.3 2.9e-36 123.2 0.4 1.6 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 GAM23404.1 - 1.4e-14 53.9 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM23404.1 - 3.6e-06 27.0 0.0 1.3e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 GAM23404.1 - 1.8e-05 23.9 2.7 5.3e-05 22.4 0.3 2.4 1 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 GAM23404.1 - 4.6e-05 22.6 0.0 9.8e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 GAM23404.1 - 0.00014 21.1 0.0 0.092 11.9 0.0 2.5 2 1 1 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 GAM23404.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM23404.1 - 0.0054 15.9 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 GAM23404.1 - 0.0097 15.5 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM23404.1 - 0.029 14.5 0.6 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.1 GAM23404.1 - 0.039 13.4 0.1 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 GAM23404.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 GAM23404.1 - 0.076 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Zn_Tnp_IS1595 PF12760.2 GAM23404.1 - 0.52 10.1 2.5 0.76 9.6 0.0 2.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain MFS_1 PF07690.11 GAM23405.1 - 6.2e-15 54.7 35.8 6.2e-15 54.7 24.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 GAM23405.1 - 0.00023 21.0 2.0 0.00073 19.5 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) Peptidase_S10 PF00450.17 GAM23406.1 - 0.095 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Peptidase_C48 PF02902.14 GAM23407.1 - 2.2e-41 141.8 2.0 2.2e-41 141.8 1.4 2.7 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain RNA_pol_Rpb2_6 PF00562.23 GAM23408.1 - 6.6e-111 370.7 3.3 1.4e-110 369.7 2.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAM23408.1 - 4.2e-29 100.9 0.1 6.8e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 GAM23408.1 - 1.8e-24 85.2 0.0 3.7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 GAM23408.1 - 3.1e-20 72.2 0.0 9.8e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 GAM23408.1 - 1.3e-18 66.6 0.0 3.4e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 GAM23408.1 - 3.6e-15 55.8 0.0 6.4e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 GAM23408.1 - 0.00018 21.3 0.9 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Metallothio_5 PF02067.10 GAM23408.1 - 0.67 10.0 4.9 1.3 9.1 3.4 1.4 1 0 0 1 1 1 0 Metallothionein family 5 Pkinase PF00069.20 GAM23409.1 - 4e-68 229.3 0.0 8.1e-68 228.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23409.1 - 3.1e-57 193.5 0.0 5.6e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM23409.1 - 1e-05 24.6 0.0 1.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBD PF00786.23 GAM23409.1 - 0.0022 18.3 0.1 0.0022 18.3 0.0 3.0 3 0 0 3 3 3 1 P21-Rho-binding domain AnfO_nitrog PF09582.5 GAM23409.1 - 0.073 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) AAA_25 PF13481.1 GAM23409.1 - 0.083 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 GAM23409.1 - 2 7.9 12.4 3.9 6.9 0.4 2.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Abhydrolase_6 PF12697.2 GAM23410.1 - 7.4e-29 101.2 0.2 9.9e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM23410.1 - 2.1e-17 63.2 0.7 5.3e-17 61.9 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM23410.1 - 1.4e-14 54.2 0.1 4.1e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 GAM23410.1 - 6.6e-07 29.1 0.1 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 GAM23410.1 - 0.00028 19.4 0.1 0.00058 18.4 0.0 1.5 2 0 0 2 2 2 1 Ndr family DLH PF01738.13 GAM23410.1 - 0.0007 18.9 0.0 0.039 13.2 0.1 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.8 GAM23410.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 GAM23410.1 - 0.023 14.9 0.1 0.056 13.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF2048 PF09752.4 GAM23410.1 - 0.027 13.3 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) DUF915 PF06028.6 GAM23410.1 - 0.038 13.0 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 GAM23410.1 - 0.055 12.9 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 GAM23410.1 - 0.071 12.5 0.0 1 8.7 0.0 2.3 3 0 0 3 3 3 0 Serine hydrolase (FSH1) DUF1100 PF06500.6 GAM23410.1 - 0.088 11.3 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_4 PF08386.5 GAM23410.1 - 0.12 12.2 0.0 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein UPF0227 PF05728.7 GAM23410.1 - 0.13 12.0 0.0 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.6 GAM23410.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CLTH PF10607.4 GAM23411.1 - 2.8e-34 117.8 0.3 4.5e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 GAM23411.1 - 3.2e-22 78.9 0.2 5e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 GAM23411.1 - 0.00028 20.5 0.0 0.00086 18.9 0.0 1.8 1 0 0 1 1 1 1 LisH NT-C2 PF10358.4 GAM23412.1 - 1.2e-24 86.4 5.5 3.3e-24 85.0 3.8 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 GAM23412.1 - 7.5e-24 83.6 1.2 4e-23 81.3 0.8 2.4 1 0 0 1 1 1 1 DIL domain ERM PF00769.14 GAM23412.1 - 0.00056 19.5 36.6 0.00056 19.5 25.4 5.4 3 2 2 5 5 5 3 Ezrin/radixin/moesin family DUF3439 PF11921.3 GAM23412.1 - 1.4 8.6 11.9 5.5 6.7 8.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MBOAT PF03062.14 GAM23413.1 - 7.2e-23 81.1 25.3 1.3e-22 80.4 17.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 GAM23413.1 - 0.001 19.1 9.4 0.0028 17.6 6.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Cpn60_TCP1 PF00118.19 GAM23414.1 - 3.4e-74 250.2 1.4 4.3e-74 249.8 1.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L27e PF01777.13 GAM23415.1 - 2.8e-26 91.4 4.6 4.6e-26 90.7 3.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 GAM23415.1 - 3.3e-05 23.4 0.2 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 1 KOW motif Cofilin_ADF PF00241.15 GAM23416.1 - 1.9e-36 124.7 0.1 2.2e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AMP-binding PF00501.23 GAM23417.1 - 5.8e-79 265.4 0.0 7.8e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM23417.1 - 2.2e-31 108.6 0.2 3.8e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM23417.1 - 5.6e-10 39.0 0.2 1.5e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM23417.1 - 1.5e-06 27.1 2.2 7.5e-06 24.8 1.5 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 GAM23417.1 - 1.3e-05 26.0 0.0 3.8e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain KR PF08659.5 GAM23417.1 - 0.0002 21.0 0.1 0.00037 20.1 0.1 1.4 1 0 0 1 1 1 1 KR domain PP-binding PF00550.20 GAM23417.1 - 0.00043 20.4 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 GAM23417.1 - 0.00057 18.8 0.1 0.0012 17.7 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM23417.1 - 0.027 14.3 0.3 0.071 13.0 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 GAM23417.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 GAM23417.1 - 0.15 12.0 0.1 8.1 6.4 0.0 2.3 1 1 1 2 2 2 0 NADH(P)-binding Lectin_legB PF00139.14 GAM23418.1 - 1.2e-18 67.4 0.1 1.5e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain Lectin_legB PF00139.14 GAM23419.1 - 2.1e-16 60.0 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain CBFB_NFYA PF02045.10 GAM23420.1 - 9.5e-28 96.5 5.9 9.5e-28 96.5 4.1 2.9 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Bac_chlorC PF02043.12 GAM23420.1 - 1.6 8.5 5.5 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Auxin_canalis PF05703.6 GAM23420.1 - 2.2 8.0 8.2 0.77 9.5 2.2 2.2 2 0 0 2 2 2 0 Auxin canalisation Gp_dh_C PF02800.15 GAM23421.1 - 4.8e-71 237.2 0.0 6.8e-71 236.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 GAM23421.1 - 1.1e-56 190.9 1.0 5.9e-56 188.6 0.1 2.2 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM23421.1 - 0.0097 15.8 0.0 0.033 14.0 0.0 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Asp PF00026.18 GAM23423.1 - 3.3e-36 125.1 0.3 4.9e-36 124.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM23423.1 - 6.5e-14 52.1 2.4 9.7e-14 51.6 1.7 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAM23423.1 - 1.3e-13 50.7 0.0 2.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF70 PF01901.11 GAM23423.1 - 0.057 12.4 0.2 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF70 Arm PF00514.18 GAM23424.1 - 1.6e-15 56.2 14.0 5.1e-06 26.1 0.3 6.3 6 1 0 6 6 6 4 Armadillo/beta-catenin-like repeat DUF59 PF01883.14 GAM23425.1 - 1.8e-08 34.2 0.0 2.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF59 UAE_UbL PF14732.1 GAM23425.1 - 0.067 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ribosom_S12_S23 PF00164.20 GAM23426.1 - 3.6e-38 129.7 1.0 4.2e-38 129.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 RhoGEF PF00621.15 GAM23427.1 - 3e-52 177.1 2.8 6.2e-52 176.0 2.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Pkinase_Tyr PF07714.12 GAM23428.1 - 3.8e-67 226.0 0.0 6.2e-67 225.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SPRY PF00622.23 GAM23428.1 - 2.1e-59 199.0 5.3 2.2e-19 69.7 0.1 3.8 3 0 0 3 3 3 3 SPRY domain Pkinase PF00069.20 GAM23428.1 - 2.5e-52 177.6 0.0 5.4e-52 176.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.12 GAM23428.1 - 7.5e-17 60.9 0.0 1.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM23428.1 - 3.3e-15 56.0 0.0 7.3e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAP18 PF06487.7 GAM23431.1 - 3.9e-32 110.5 0.0 5.6e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Mucin PF01456.12 GAM23431.1 - 0.0069 16.1 10.2 0.011 15.4 7.1 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Dicty_REP PF05086.7 GAM23431.1 - 0.037 11.7 3.1 0.041 11.6 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Clat_adaptor_s PF01217.15 GAM23431.1 - 0.051 13.2 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Gag_p17 PF00540.13 GAM23431.1 - 0.1 12.3 0.1 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 gag gene protein p17 (matrix protein) E1-E2_ATPase PF00122.15 GAM23432.1 - 8.6e-32 110.0 2.4 1.4e-31 109.3 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 GAM23432.1 - 1.2e-24 87.5 0.4 2.5e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM23432.1 - 6.9e-23 82.1 0.0 3.2e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 GAM23432.1 - 4.8e-13 49.0 0.2 4.8e-13 49.0 0.1 2.5 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 GAM23432.1 - 0.00018 21.4 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 GAM23432.1 - 0.034 13.6 0.0 0.078 12.4 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus RbsD_FucU PF05025.8 GAM23432.1 - 0.083 13.2 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family Flavodoxin_3 PF12641.2 GAM23432.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain LIM PF00412.17 GAM23433.1 - 1.2e-63 210.9 58.0 6.6e-17 61.3 1.0 5.2 5 0 0 5 5 5 5 LIM domain FNIP PF05725.7 GAM23434.1 - 1.7e-26 91.9 5.7 1.4e-12 47.3 0.1 4.3 3 1 1 4 4 4 3 FNIP Repeat DUF1769 PF08588.5 GAM23434.1 - 0.013 15.4 0.6 33 4.5 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1769) Glyco_hydro_18 PF00704.23 GAM23435.1 - 2.5e-18 66.6 2.1 2.5e-18 66.6 1.5 2.9 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 DUF605 PF04652.11 GAM23435.1 - 5.2 6.3 37.0 7.5 5.8 25.7 1.1 1 0 0 1 1 1 0 Vta1 like zf-FPG_IleRS PF06827.9 GAM23436.1 - 0.029 14.0 0.1 0.082 12.5 0.0 1.9 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF525 PF04379.9 GAM23437.1 - 2.3e-21 75.5 0.1 5.7e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF525) F-box PF00646.28 GAM23437.1 - 0.0044 16.6 0.4 0.011 15.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain SMI1_KNR4 PF09346.5 GAM23437.1 - 0.042 13.8 0.3 0.29 11.1 0.2 2.1 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) F-box-like PF12937.2 GAM23437.1 - 0.24 11.1 3.1 1.6 8.4 0.4 2.8 3 0 0 3 3 3 0 F-box-like SSP160 PF06933.6 GAM23437.1 - 9.9 3.9 11.4 14 3.4 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Podoplanin PF05808.6 GAM23438.1 - 5.2 6.6 7.4 7.6 6.0 5.1 1.3 1 0 0 1 1 1 0 Podoplanin PIG-U PF06728.8 GAM23439.1 - 2.8e-113 378.6 45.6 3.7e-113 378.2 31.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF912 PF06024.7 GAM23439.1 - 0.0096 15.9 0.1 0.0096 15.9 0.1 2.8 4 0 0 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3481 PF11980.3 GAM23439.1 - 0.03 14.1 1.8 0.047 13.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) DUF1183 PF06682.7 GAM23439.1 - 2.4 7.7 6.0 3.3 7.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1183) Cullin PF00888.17 GAM23440.1 - 3.3e-158 527.8 16.3 3.3e-158 527.8 11.3 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 GAM23440.1 - 6.1e-30 102.8 4.2 3e-29 100.6 3.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain ALS_ss_C PF10369.4 GAM23440.1 - 0.021 14.5 0.7 0.062 13.0 0.5 1.8 1 0 0 1 1 1 0 Small subunit of acetolactate synthase GlutR_dimer PF00745.15 GAM23440.1 - 0.041 13.8 4.7 0.53 10.2 0.0 3.7 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain DDE_Tnp_4 PF13359.1 GAM23441.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM23441.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain SOG2 PF10428.4 GAM23442.1 - 0.036 12.7 2.3 0.035 12.7 1.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dicty_REP PF05086.7 GAM23442.1 - 4.2 5.0 6.4 6.3 4.4 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rieske PF00355.21 GAM23443.1 - 1.3e-17 63.1 0.0 2.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 GAM23443.1 - 5.2e-12 45.8 0.1 8.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region VCBS PF13517.1 GAM23444.1 - 0.0027 18.0 0.1 0.0085 16.4 0.1 1.9 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAM23444.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 FG-GAP repeat BBS2_Mid PF14783.1 GAM23444.1 - 0.016 15.0 0.0 0.058 13.1 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Sld5 PF05916.6 GAM23445.1 - 2.3e-18 66.4 0.1 3.2e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3692 PF12469.3 GAM23445.1 - 0.1 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Peptidase_M28 PF04389.12 GAM23446.1 - 2.6e-36 125.0 0.0 4e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 GAM23446.1 - 0.00052 19.3 0.0 0.00071 18.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DAP3 PF10236.4 GAM23447.1 - 0.00027 19.9 0.1 0.0007 18.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DUF3418 PF11898.3 GAM23447.1 - 0.0045 15.4 0.2 0.008 14.6 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3418) PsbQ PF05757.6 GAM23447.1 - 0.1 11.9 0.2 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Hydantoinase_B PF02538.9 GAM23449.1 - 6.5e-187 621.9 0.1 8e-187 621.6 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 GAM23449.1 - 7.7e-90 300.9 0.0 1.4e-89 300.0 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 GAM23449.1 - 1.5e-40 138.5 0.0 1.4e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ThiS PF02597.15 GAM23449.1 - 0.025 15.0 0.0 0.089 13.2 0.0 1.9 2 0 0 2 2 2 0 ThiS family UPF0542 PF15086.1 GAM23450.1 - 0.069 12.8 2.1 4.9 6.9 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0542 Myb_DNA-binding PF00249.26 GAM23451.1 - 2.3e-24 85.1 4.2 1.2e-10 41.2 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM23451.1 - 9.7e-23 80.0 1.3 1.5e-12 47.4 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain TFIIA PF03153.8 GAM23451.1 - 0.00041 20.3 9.9 0.00076 19.4 6.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Myb_DNA-bind_4 PF13837.1 GAM23451.1 - 0.00056 19.9 12.2 0.0098 16.0 0.0 3.9 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain RhoGEF PF00621.15 GAM23452.1 - 1.7e-40 138.8 6.4 1.7e-40 138.8 4.4 4.2 3 1 2 5 5 5 1 RhoGEF domain IQ PF00612.22 GAM23452.1 - 0.001 18.5 1.5 0.0025 17.2 1.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cnd3 PF12719.2 GAM23453.1 - 1.4e-35 122.7 4.7 1.4e-35 122.7 3.3 3.5 4 1 1 5 5 5 2 Nuclear condensing complex subunits, C-term domain GATA PF00320.22 GAM23454.1 - 6.5e-11 41.3 1.6 1.2e-10 40.5 1.1 1.5 1 0 0 1 1 1 1 GATA zinc finger AT_hook PF02178.14 GAM23454.1 - 0.43 10.4 7.5 0.82 9.5 5.2 1.5 1 0 0 1 1 1 0 AT hook motif Macoilin PF09726.4 GAM23454.1 - 0.46 8.6 14.5 0.67 8.1 10.0 1.1 1 0 0 1 1 1 0 Transmembrane protein EB PF01683.13 GAM23457.1 - 6.2 6.9 74.2 1 9.4 7.2 7.9 2 2 4 6 6 6 0 EB module Prenyltrans PF00432.16 GAM23460.1 - 5.8e-44 147.3 7.7 6.6e-12 44.7 0.1 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 GAM23460.1 - 8.3e-26 90.6 0.1 5.3e-15 55.8 0.0 4.1 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM23460.1 - 2.8e-05 24.0 0.1 0.24 11.4 0.0 3.8 2 1 2 4 4 4 3 Prenyltransferase-like Fcf2 PF08698.6 GAM23461.1 - 1.6e-18 66.4 1.1 1.6e-18 66.4 0.7 2.3 2 1 1 3 3 3 1 Fcf2 pre-rRNA processing HSA PF07529.8 GAM23461.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.7 4 0 0 4 4 4 0 HSA TIG PF01833.19 GAM23462.1 - 7.4e-17 61.1 53.1 1.9e-06 27.7 1.1 6.3 4 2 2 6 6 6 4 IPT/TIG domain N2227 PF07942.7 GAM23463.1 - 1.2e-52 178.5 0.1 1.7e-33 115.7 0.1 2.3 1 1 1 2 2 2 2 N2227-like protein Methyltransf_12 PF08242.7 GAM23463.1 - 4.5e-05 23.8 1.3 0.00079 19.8 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM23463.1 - 0.00011 21.9 2.1 0.00069 19.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23463.1 - 0.00026 20.5 0.1 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23463.1 - 0.00086 19.7 0.0 0.0031 17.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23463.1 - 0.0087 15.1 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF2572 PF10833.3 GAM23463.1 - 8.1 5.7 8.0 7.1 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) Rap_GAP PF02145.10 GAM23464.1 - 1.5e-58 197.2 0.0 2.2e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP RasGAP PF00616.14 GAM23465.1 - 1.3e-34 119.5 0.1 5.9e-34 117.4 0.1 2.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 GAM23465.1 - 1.4e-15 57.4 2.2 1.2e-14 54.5 1.0 2.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF4419 PF14388.1 GAM23466.1 - 4.6e-66 223.0 0.5 5.3e-66 222.8 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DnaJ_CXXCXGXG PF00684.14 GAM23467.1 - 0.00029 20.8 18.9 0.05 13.6 3.7 3.3 1 1 1 2 2 2 2 DnaJ central domain zf-rbx1 PF12678.2 GAM23467.1 - 0.16 12.0 9.3 0.14 12.3 1.9 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger WWbp PF10349.4 GAM23467.1 - 2.6 8.9 16.5 3.6 8.4 11.5 1.2 1 0 0 1 1 1 0 WW-domain ligand protein HSP70 PF00012.15 GAM23468.1 - 9.2e-258 856.1 5.7 1e-257 855.9 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM23468.1 - 7.6e-17 60.8 0.2 1.3e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 GAM23468.1 - 0.013 15.1 0.0 0.035 13.7 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 GAM23468.1 - 0.013 14.8 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 GAM23468.1 - 0.018 14.1 1.0 0.093 11.8 0.0 2.4 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DDR PF08841.5 GAM23468.1 - 0.029 13.1 0.2 0.24 10.1 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF3811 PF11656.3 GAM23468.1 - 8.4 6.5 8.6 0.6 10.2 2.0 2.0 2 0 0 2 2 2 0 YjbD family (DUF3811) IncA PF04156.9 GAM23469.1 - 0.0056 16.3 23.9 0.0056 16.3 16.5 5.9 2 1 3 5 5 5 2 IncA protein ERCC4 PF02732.10 GAM23471.1 - 1.9e-17 63.3 0.4 5.3e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain UPF0075 PF03702.9 GAM23472.1 - 3.4e-144 480.2 0.1 3.9e-144 480.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) ATP_bind_1 PF03029.12 GAM23473.1 - 4e-82 275.3 0.1 6.9e-82 274.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 GAM23473.1 - 1.9e-08 33.9 0.2 2.2e-07 30.4 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 GAM23473.1 - 5.4e-06 25.3 2.6 7.6e-05 21.5 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit cobW PF02492.14 GAM23473.1 - 6.5e-06 25.7 0.0 0.011 15.2 0.0 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 GAM23473.1 - 1.4e-05 24.4 0.0 0.006 15.8 0.0 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 GAM23473.1 - 1.4e-05 25.1 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 GAM23473.1 - 2.7e-05 23.4 0.0 0.0012 18.1 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B CbiA PF01656.18 GAM23473.1 - 4.8e-05 22.8 0.0 9.7e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 GAM23473.1 - 9.4e-05 22.3 0.2 0.00047 20.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM23473.1 - 0.00013 22.1 0.0 0.0004 20.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 GAM23473.1 - 0.00077 19.1 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 GAM23473.1 - 0.0012 19.2 1.3 0.025 14.8 0.0 2.8 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.17 GAM23473.1 - 0.0017 17.8 0.0 0.024 14.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Miro PF08477.8 GAM23473.1 - 0.0019 18.6 0.1 1.8 9.0 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_24 PF13479.1 GAM23473.1 - 0.0022 17.6 0.4 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM23473.1 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain PduV-EutP PF10662.4 GAM23473.1 - 0.0025 17.3 0.1 0.023 14.1 0.0 2.5 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 GAM23473.1 - 0.0026 17.2 0.6 0.058 12.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 GAM23473.1 - 0.0061 15.3 0.0 1.9 7.2 0.0 2.3 2 0 0 2 2 2 1 ArgK protein Ras PF00071.17 GAM23473.1 - 0.0085 15.4 0.0 2.2 7.6 0.0 2.6 2 1 0 2 2 2 1 Ras family AAA_33 PF13671.1 GAM23473.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAM23473.1 - 0.011 14.9 5.5 0.3 10.2 0.0 3.2 3 1 1 4 4 4 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 GAM23473.1 - 0.014 14.2 0.4 0.056 12.2 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.7 GAM23473.1 - 0.02 14.1 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_19 PF13245.1 GAM23473.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 GAM23473.1 - 0.027 15.2 3.5 0.036 14.8 0.0 2.4 2 1 0 2 2 1 0 AAA domain UvrD_C PF13361.1 GAM23473.1 - 0.028 13.8 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 GAM23473.1 - 0.033 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 GAM23473.1 - 0.034 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 GAM23473.1 - 0.042 13.3 0.0 0.089 12.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 GAM23473.1 - 0.043 13.5 0.0 0.24 11.1 0.0 2.1 1 1 0 1 1 1 0 NTPase KAP_NTPase PF07693.9 GAM23473.1 - 0.055 12.4 0.0 0.18 10.7 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.1 GAM23473.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM23473.1 - 0.11 12.8 0.1 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 GAM23473.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.15 GAM23473.1 - 0.11 12.1 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF258 PF03193.11 GAM23473.1 - 0.13 11.3 0.1 0.48 9.6 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DTW PF03942.10 GAM23474.1 - 1.3e-29 102.9 0.1 6.4e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 DTW domain zf-B_box PF00643.19 GAM23474.1 - 0.023 14.5 3.5 0.042 13.7 2.4 1.4 1 0 0 1 1 1 0 B-box zinc finger zf-RING_3 PF14369.1 GAM23474.1 - 1.5 8.8 5.1 30 4.7 1.2 2.6 2 0 0 2 2 2 0 zinc-finger FNIP PF05725.7 GAM23475.1 - 2.9e-45 151.9 32.8 4.1e-09 36.2 0.7 6.0 2 1 5 8 8 8 7 FNIP Repeat LRR_8 PF13855.1 GAM23475.1 - 0.021 14.5 9.1 0.04 13.6 0.7 4.1 3 1 1 4 4 4 0 Leucine rich repeat McyA_C PF12593.3 GAM23475.1 - 2.2 8.0 5.2 1.5 8.6 0.5 2.2 2 0 0 2 2 2 0 Microcystin synthetase C terminal RHSP PF07999.6 GAM23476.1 - 0.0015 17.1 0.1 1 7.8 0.0 2.1 2 0 0 2 2 2 2 Retrotransposon hot spot protein NACHT PF05729.7 GAM23476.1 - 0.024 14.2 0.0 0.069 12.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 GAM23476.1 - 0.038 14.1 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 GAM23476.1 - 0.04 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 GAM23476.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 GAM23476.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_C48 PF02902.14 GAM23478.1 - 1.9e-08 34.2 0.0 2.3e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DKCLD PF08068.7 GAM23478.1 - 0.12 12.2 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 DKCLD (NUC011) domain DUF489 PF04356.7 GAM23479.1 - 0.18 11.3 4.5 0.39 10.2 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF572 PF04502.8 GAM23479.1 - 1 8.4 15.3 1.7 7.7 10.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Med22 PF06179.7 GAM23480.1 - 1.5e-23 82.9 11.2 2.1e-23 82.4 7.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.7 GAM23480.1 - 0.017 15.4 1.0 0.017 15.4 0.7 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Telomere_reg-2 PF10193.4 GAM23480.1 - 0.18 12.1 3.3 1.7 8.9 0.1 2.6 1 1 2 3 3 3 0 Telomere length regulation protein DUF848 PF05852.6 GAM23480.1 - 4.2 7.2 7.9 8.1 6.2 4.9 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SR-25 PF10500.4 GAM23480.1 - 4.9 6.5 15.0 7.6 5.9 10.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4163 PF13739.1 GAM23480.1 - 9.2 7.1 10.7 11 6.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) ABC2_membrane PF01061.19 GAM23481.1 - 1.1e-74 250.1 35.1 6.4e-41 139.8 9.5 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 GAM23481.1 - 4e-44 150.2 0.4 9.1e-22 77.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM23481.1 - 5.9e-09 36.3 0.0 0.017 15.1 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAM23481.1 - 9.9e-09 35.4 0.0 0.001 19.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAM23481.1 - 1.8e-08 33.7 0.3 6.4e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM23481.1 - 4.7e-08 33.2 0.0 0.0062 16.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM23481.1 - 2.6e-07 30.0 0.0 0.0013 18.2 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 GAM23481.1 - 2.3e-06 27.6 0.1 0.2 11.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAM23481.1 - 5.4e-06 26.3 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM23481.1 - 8.2e-06 26.6 0.0 0.056 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAM23481.1 - 9e-06 26.0 0.0 0.048 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 GAM23481.1 - 7.9e-05 21.9 0.3 3.5 6.7 0.0 3.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 GAM23481.1 - 9.2e-05 22.6 0.1 0.76 9.9 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAM23481.1 - 0.00016 20.4 0.1 0.048 12.3 0.1 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 GAM23481.1 - 0.00022 21.1 0.0 0.98 9.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAM23481.1 - 0.00025 20.2 45.6 0.014 14.4 10.7 3.3 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_15 PF13175.1 GAM23481.1 - 0.00027 20.1 0.0 0.1 11.5 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 GAM23481.1 - 0.0003 20.5 0.0 0.8 9.3 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_25 PF13481.1 GAM23481.1 - 0.00033 20.1 0.0 1.4 8.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 GAM23481.1 - 0.00041 19.5 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 GAM23481.1 - 0.001 19.0 0.0 1.7 8.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAM23481.1 - 0.0017 18.2 0.0 0.37 10.7 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 GAM23481.1 - 0.0027 16.6 0.0 0.8 8.5 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 GAM23481.1 - 0.0035 17.4 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Adeno_IVa2 PF02456.10 GAM23481.1 - 0.0037 15.9 0.3 0.29 9.7 0.1 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein cobW PF02492.14 GAM23481.1 - 0.0055 16.1 0.9 1.1 8.6 0.1 2.9 3 1 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 GAM23481.1 - 0.0056 16.3 0.1 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 GAM23481.1 - 0.0068 15.9 0.1 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 GAM23481.1 - 0.012 15.3 0.1 8.2 6.1 0.0 3.4 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.1 GAM23481.1 - 0.014 15.7 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.6 GAM23481.1 - 0.018 14.5 1.5 3.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_19 PF13245.1 GAM23481.1 - 0.02 14.6 0.0 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_5 PF07728.9 GAM23481.1 - 0.021 14.5 0.1 6.2 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 GAM23481.1 - 0.032 13.6 0.2 2.3 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 GAM23481.1 - 0.044 13.3 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.7 GAM23481.1 - 0.047 13.3 2.2 0.57 9.8 0.1 2.7 2 0 0 2 2 2 0 CDR ABC transporter UPF0079 PF02367.12 GAM23481.1 - 0.053 13.1 0.1 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 GAM23481.1 - 0.09 13.2 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Mg_chelatase PF01078.16 GAM23481.1 - 0.12 11.5 1.0 4.5 6.3 0.1 2.7 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 GAM23481.1 - 0.16 11.4 0.1 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgJ PF01960.13 GAM23482.1 - 1.2e-151 504.5 13.8 1.4e-151 504.3 9.6 1.0 1 0 0 1 1 1 1 ArgJ family ATG_C PF09333.6 GAM23482.1 - 0.044 13.9 0.3 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 ATG C terminal domain Alpha_L_fucos PF01120.12 GAM23483.1 - 3.1e-55 187.4 0.1 3.9e-55 187.1 0.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Lyase_N PF09092.6 GAM23483.1 - 0.1 12.1 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lyase, N terminal CENP-B_dimeris PF09026.5 GAM23484.1 - 0.033 14.4 2.1 0.8 9.9 1.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain E1-E2_ATPase PF00122.15 GAM23485.1 - 1.2e-11 44.0 0.0 4.3e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Dynactin PF12455.3 GAM23486.1 - 3.2e-44 150.9 7.7 3.2e-44 150.9 5.3 4.5 3 2 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 GAM23486.1 - 7.3e-24 83.2 0.4 1.2e-23 82.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2804 PF10974.3 GAM23487.1 - 1.2e-91 307.0 0.7 1.4e-91 306.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) DLIC PF05783.6 GAM23489.1 - 5.2e-100 335.3 1.5 5.9e-100 335.1 1.0 1.0 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) MRC1 PF09444.5 GAM23489.1 - 0.051 13.9 0.4 0.051 13.9 0.3 1.7 2 0 0 2 2 2 0 MRC1-like domain Ribosomal_L28e PF01778.12 GAM23490.1 - 3.6e-30 104.7 0.4 4.8e-30 104.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF883 PF05957.8 GAM23490.1 - 0.21 12.0 4.3 0.15 12.4 1.9 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2962 PF11176.3 GAM23491.1 - 1e-31 109.5 4.8 1.3e-31 109.2 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3753 PF12575.3 GAM23492.1 - 0.037 13.8 0.1 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) HECT PF00632.20 GAM23493.1 - 3.7e-88 295.7 0.2 3.7e-88 295.7 0.1 2.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) SET PF00856.23 GAM23494.1 - 9.6e-14 52.0 0.0 9.8e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 GAM23494.1 - 5.9e-05 22.8 12.5 5.9e-05 22.8 8.6 3.1 4 0 0 4 4 4 1 MYND finger DUF1084 PF06454.6 GAM23495.1 - 4.7e-11 42.2 22.2 2.5e-10 39.8 15.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2116 PF09889.4 GAM23495.1 - 0.21 11.4 0.0 0.21 11.4 0.0 4.0 6 0 0 6 6 6 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Str_synth PF03088.11 GAM23496.1 - 1.5e-20 73.0 0.3 2.9e-18 65.6 0.0 3.9 3 1 1 4 4 4 1 Strictosidine synthase SGL PF08450.7 GAM23496.1 - 3.4e-18 65.9 0.0 6.6e-18 64.9 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 GAM23496.1 - 2e-09 36.9 0.4 0.067 13.1 0.0 5.6 5 0 0 5 5 5 3 NHL repeat Arylesterase PF01731.15 GAM23496.1 - 1.3e-05 25.0 0.2 0.00018 21.3 0.0 2.9 4 0 0 4 4 4 1 Arylesterase NUDIX PF00293.23 GAM23497.1 - 6.3e-10 38.8 0.0 9.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Epimerase PF01370.16 GAM23498.1 - 5.8e-53 179.7 0.0 9.1e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM23498.1 - 2.2e-06 26.7 0.1 7.7e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM23498.1 - 6e-05 22.0 3.3 0.00032 19.6 0.0 2.7 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAM23498.1 - 0.00019 20.4 1.1 0.0019 17.1 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein DUF2763 PF10961.3 GAM23499.1 - 9.9e-16 57.9 8.1 1.2e-15 57.6 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2763) GRP PF07172.6 GAM23499.1 - 0.91 10.0 28.0 1.3 9.5 19.4 1.2 1 0 0 1 1 1 0 Glycine rich protein family CH PF00307.26 GAM23500.1 - 5.5e-09 36.0 0.0 7.5e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain DZR PF12773.2 GAM23500.1 - 5.1e-05 22.9 0.6 0.00011 21.9 0.4 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM23500.1 - 0.00021 20.3 8.1 0.00051 19.1 5.6 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM23500.1 - 0.0041 16.5 5.8 0.0088 15.5 4.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zf-NADH-PPase PF09297.6 GAM23500.1 - 1.8 8.1 12.5 2.9 7.4 1.9 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain N6-adenineMlase PF10237.4 GAM23501.1 - 1.1e-48 164.9 0.3 1.3e-48 164.6 0.2 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 GAM23501.1 - 0.004 16.5 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 XAP5 PF04921.9 GAM23502.1 - 5.5e-85 284.7 11.1 5.5e-85 284.7 7.7 2.3 1 1 1 2 2 2 1 XAP5, circadian clock regulator Peptidase_S64 PF08192.6 GAM23502.1 - 2.9 6.1 14.9 3.7 5.7 10.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_47 PF01532.15 GAM23503.1 - 2.2e-133 445.2 0.4 2.7e-133 444.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Phosducin PF02114.11 GAM23504.1 - 1.6e-27 95.9 4.6 4.1e-27 94.5 3.2 1.6 1 1 0 1 1 1 1 Phosducin EF-1_beta_acid PF10587.4 GAM23504.1 - 0.0021 18.1 5.8 0.0021 18.1 4.0 3.4 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region Neur_chan_memb PF02932.11 GAM23504.1 - 1.3 8.8 3.3 1.8 8.3 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RWD PF05773.17 GAM23505.1 - 5.5e-16 58.4 0.0 1.2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain Peptidase_M3 PF01432.15 GAM23506.1 - 2.2e-129 432.4 0.1 3.2e-129 431.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 GAM23506.1 - 0.089 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Effector protein Peptidase_M50B PF13398.1 GAM23506.1 - 0.22 10.8 0.2 0.42 9.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like HD_4 PF13328.1 GAM23507.1 - 5.3e-28 97.6 0.8 6.5e-28 97.3 0.6 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 GAM23507.1 - 0.00024 21.1 2.3 0.00044 20.2 1.6 1.4 1 0 0 1 1 1 1 HD domain Peptidase_S49 PF01343.13 GAM23507.1 - 0.1 12.3 0.4 0.21 11.3 0.3 1.5 1 1 0 1 1 1 0 Peptidase family S49 Colicin PF01024.14 GAM23507.1 - 0.14 11.7 0.5 3.7 7.0 0.1 2.1 1 1 1 2 2 2 0 Colicin pore forming domain Peptidase_C15 PF01470.12 GAM23508.1 - 4.9e-19 68.9 0.3 2.1e-15 57.0 0.0 2.0 1 1 1 2 2 2 2 Pyroglutamyl peptidase Imm30 PF15594.1 GAM23508.1 - 0.0061 16.6 0.1 0.034 14.2 0.0 2.1 2 0 0 2 2 2 1 Immunity protein 30 VWA_2 PF13519.1 GAM23510.1 - 4.4e-13 49.6 0.1 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.10 GAM23510.1 - 0.00013 21.3 0.1 0.011 15.0 0.1 2.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 GAM23510.1 - 0.00046 20.6 1.8 0.00065 20.1 0.0 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain VWA_CoxE PF05762.9 GAM23510.1 - 0.02 14.0 0.6 0.71 8.9 0.0 2.7 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein zf-Sec23_Sec24 PF04810.10 GAM23510.1 - 0.035 13.6 0.5 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Aldolase_II PF00596.16 GAM23511.1 - 1.2e-26 93.3 0.0 6.9e-13 48.5 0.0 2.1 1 1 1 2 2 2 2 Class II Aldolase and Adducin N-terminal domain DNAPolymera_Pol PF11590.3 GAM23511.1 - 0.0061 16.1 0.4 0.86 9.3 0.1 2.7 2 0 0 2 2 2 2 DNA polymerase catalytic subunit Pol Na_Ca_ex PF01699.19 GAM23512.1 - 2.3e-22 79.0 26.2 6e-13 48.5 3.8 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAM23512.1 - 1.2e-13 51.2 7.9 1.2e-13 51.2 5.4 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF307) Peptidase_C54 PF03416.14 GAM23514.1 - 2.2e-99 332.1 0.2 2.2e-99 332.1 0.1 1.6 2 0 0 2 2 2 1 Peptidase family C54 Dabb PF07876.7 GAM23514.1 - 0.0084 16.5 0.8 0.27 11.6 0.1 2.5 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain EFP_N PF08207.7 GAM23515.1 - 3e-08 33.4 0.1 5.7e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Peptidase_M24 PF00557.19 GAM23516.1 - 2.2e-27 96.0 0.0 3.3e-27 95.4 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 zf-RING_2 PF13639.1 GAM23517.1 - 7.6e-13 48.0 5.5 1.4e-12 47.2 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 GAM23517.1 - 4.4e-07 29.4 4.9 9.1e-07 28.4 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM23517.1 - 2.6e-06 27.3 6.4 4.6e-06 26.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM23517.1 - 1.2e-05 25.3 5.0 3.2e-05 23.9 3.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM23517.1 - 2.1e-05 24.1 4.1 3.3e-05 23.5 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM23517.1 - 3.7e-05 23.3 2.7 6.3e-05 22.5 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3021 PF11457.3 GAM23517.1 - 8.9e-05 22.3 4.2 0.00015 21.6 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3021) zf-Apc11 PF12861.2 GAM23517.1 - 0.0018 18.0 1.1 0.0041 16.9 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 GAM23517.1 - 0.13 12.2 8.2 4.2 7.3 5.7 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain SUR7 PF06687.7 GAM23517.1 - 0.15 11.5 8.3 0.24 10.9 5.8 1.2 1 0 0 1 1 1 0 SUR7/PalI family zf-RING_UBOX PF13445.1 GAM23517.1 - 0.48 10.1 3.3 0.83 9.4 0.8 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 GAM23517.1 - 0.62 9.7 2.8 1.1 8.9 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ROK PF00480.15 GAM23518.1 - 1.6e-33 116.0 0.2 2.3e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.11 GAM23518.1 - 0.03 13.1 0.2 0.046 12.5 0.1 1.3 1 0 0 1 1 1 0 Glucokinase Frag1 PF10277.4 GAM23519.1 - 5.6e-20 71.7 17.0 6.2e-20 71.6 11.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 GAM23519.1 - 0.00014 21.2 4.0 0.00022 20.6 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF1129 PF06570.6 GAM23519.1 - 0.0026 17.0 5.4 0.0034 16.7 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Chs3p PF12271.3 GAM23519.1 - 0.0044 16.0 7.4 0.0056 15.6 5.1 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ABC2_membrane_5 PF13346.1 GAM23519.1 - 0.034 13.4 15.2 0.055 12.7 10.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MFS_1 PF07690.11 GAM23519.1 - 0.65 8.6 15.3 0.025 13.3 2.0 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF1385 PF07136.6 GAM23519.1 - 1 8.3 7.0 1.4 7.9 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) FNIP PF05725.7 GAM23520.1 - 2.1e-43 145.9 42.9 2.5e-09 36.9 2.0 8.1 4 2 5 9 9 9 8 FNIP Repeat ShlB PF03865.8 GAM23520.1 - 0.061 12.0 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Ank_2 PF12796.2 GAM23521.1 - 1.4e-05 25.3 0.8 0.0065 16.7 0.6 3.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM23521.1 - 1.8e-05 24.5 1.6 1.8 9.0 0.0 5.3 4 1 1 5 5 5 2 Ankyrin repeat Ank PF00023.25 GAM23521.1 - 0.0024 17.6 1.6 1.9 8.4 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 GAM23521.1 - 0.017 15.5 6.6 6.3 7.4 0.0 5.5 8 0 0 8 8 8 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM23521.1 - 0.25 11.6 1.5 6.6 7.1 0.1 3.5 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Methyltransf_11 PF08241.7 GAM23522.1 - 1.5e-18 67.0 0.0 3.7e-18 65.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM23522.1 - 4e-14 52.6 0.0 5.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23522.1 - 6.7e-13 48.4 0.0 1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23522.1 - 2.4e-11 44.1 0.0 6.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23522.1 - 5.4e-11 42.8 0.0 1.1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23522.1 - 9.1e-09 35.6 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM23522.1 - 1.9e-07 31.1 0.0 7.4e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23522.1 - 1.5e-06 27.5 0.0 4.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 GAM23522.1 - 5.9e-05 22.1 0.0 0.0033 16.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase N6_N4_Mtase PF01555.13 GAM23522.1 - 0.00086 18.8 0.0 0.33 10.3 0.0 2.3 2 1 0 2 2 2 2 DNA methylase Methyltransf_8 PF05148.10 GAM23522.1 - 0.0016 18.1 0.0 0.0029 17.2 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.1 GAM23522.1 - 0.0063 17.3 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM23522.1 - 0.0079 16.2 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.6 GAM23522.1 - 0.02 14.3 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RrnaAD PF00398.15 GAM23522.1 - 0.023 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 GAM23522.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 GAM23522.1 - 0.029 13.7 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.7 GAM23522.1 - 0.077 12.5 0.0 1.6 8.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.6 GAM23522.1 - 0.096 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ThiF PF00899.16 GAM23523.1 - 6e-51 171.8 2.3 3.7e-32 110.9 0.1 2.8 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 GAM23523.1 - 4e-33 112.7 2.0 3.9e-25 87.2 0.2 3.2 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 GAM23523.1 - 4e-30 104.5 0.0 9e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 GAM23523.1 - 6.3e-24 83.1 4.1 9.8e-21 72.8 1.1 2.6 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 GAM23523.1 - 0.03 13.8 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 MoeZ/MoeB domain Shikimate_DH PF01488.15 GAM23523.1 - 0.032 14.3 0.1 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase E2_bind PF08825.5 GAM23523.1 - 0.033 13.9 0.8 0.17 11.6 0.0 2.7 3 0 0 3 3 3 0 E2 binding domain vWF_A PF12450.3 GAM23523.1 - 0.053 13.2 0.0 2.5 7.8 0.0 2.8 2 0 0 2 2 2 0 von Willebrand factor LEA_2 PF03168.8 GAM23523.1 - 0.093 13.1 0.2 0.8 10.1 0.0 2.5 3 0 0 3 3 3 0 Late embryogenesis abundant protein Gln-synt_C PF00120.19 GAM23524.1 - 1.8e-57 194.4 0.0 2.2e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF1641 PF07849.6 GAM23524.1 - 0.09 12.4 0.1 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Lipase_3 PF01764.20 GAM23525.1 - 1.3e-20 73.4 0.0 2.9e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF1350 PF07082.6 GAM23525.1 - 0.11 11.5 0.7 0.21 10.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1350) Dynamin_M PF01031.15 GAM23526.1 - 7.3e-107 356.5 0.1 1.3e-106 355.6 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 GAM23526.1 - 2.4e-60 203.1 0.6 2.8e-59 199.6 0.0 2.5 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 GAM23526.1 - 4.1e-33 113.1 2.6 4.1e-33 113.1 1.8 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 GAM23526.1 - 0.00025 20.9 0.2 0.0011 18.8 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM23526.1 - 0.014 15.8 0.0 0.049 14.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PAT1 PF09770.4 GAM23526.1 - 2.9 6.0 43.5 4 5.5 30.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4166 PF13761.1 GAM23527.1 - 6.9e-28 97.5 0.1 3e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4166) DUF1731 PF08338.6 GAM23527.1 - 1.6e-12 46.6 0.0 3.4e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.16 GAM23527.1 - 7.4e-09 35.3 0.0 1.2e-07 31.4 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DAO PF01266.19 GAM23527.1 - 5.3e-07 28.8 0.8 0.00015 20.8 0.0 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM23527.1 - 5.9e-06 25.3 0.6 1.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 GAM23527.1 - 1.1e-05 24.6 10.5 0.00066 18.8 0.2 3.9 3 1 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 GAM23527.1 - 2.3e-05 24.3 3.4 0.00021 21.2 0.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM23527.1 - 0.00018 21.4 1.0 0.046 13.6 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 GAM23527.1 - 0.00087 19.3 2.4 0.0032 17.4 0.0 2.5 2 1 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 GAM23527.1 - 0.015 15.1 1.6 0.016 15.1 0.0 1.9 2 0 0 2 2 1 0 short chain dehydrogenase SE PF08491.5 GAM23527.1 - 0.019 13.7 0.0 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase Glyco_trans_4_4 PF13579.1 GAM23527.1 - 0.02 15.0 0.1 0.02 15.0 0.0 2.8 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain Thi4 PF01946.12 GAM23527.1 - 0.044 12.8 1.9 0.071 12.1 0.2 1.9 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.9 GAM23527.1 - 0.049 12.2 0.6 0.1 11.2 0.4 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Glyco_transf_4 PF13439.1 GAM23527.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pyr_redox PF00070.22 GAM23527.1 - 0.14 12.5 4.4 0.097 13.0 1.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 GAM23527.1 - 0.15 11.2 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 GAM23527.1 - 0.19 11.7 0.1 28 4.7 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 GAM23527.1 - 1.3 8.6 3.0 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RhoGEF PF00621.15 GAM23528.1 - 1.2e-45 155.6 6.9 1.2e-45 155.6 4.8 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM23528.1 - 3.7e-06 27.0 2.9 5.1e-06 26.6 0.1 2.6 2 1 0 2 2 2 1 PH domain IQ PF00612.22 GAM23528.1 - 0.04 13.5 4.6 0.099 12.3 3.2 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif FNIP PF05725.7 GAM23529.1 - 6.8e-12 45.1 10.1 0.00018 21.3 0.1 5.5 5 0 0 5 5 5 5 FNIP Repeat TPR_2 PF07719.12 GAM23532.1 - 6.1e-06 25.7 0.0 1.8e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM23532.1 - 1.4e-05 24.5 0.1 2.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM23532.1 - 0.00048 19.7 0.2 0.00048 19.7 0.1 2.1 3 0 0 3 3 3 1 TPR repeat Cgr1 PF03879.9 GAM23533.1 - 0.00013 22.0 22.1 0.00013 22.0 15.3 2.8 1 1 2 3 3 3 1 Cgr1 family Prog_receptor PF02161.10 GAM23533.1 - 0.7 8.6 8.5 0.92 8.2 5.9 1.2 1 0 0 1 1 1 0 Progesterone receptor Ras PF00071.17 GAM23534.1 - 4.9e-57 191.8 0.2 6.3e-57 191.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23534.1 - 4.4e-19 69.1 0.1 9.6e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM23534.1 - 3.2e-13 49.2 0.0 4.7e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM23534.1 - 1.9e-06 27.8 0.1 8.8e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM23534.1 - 0.00014 21.3 0.1 0.00022 20.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM23534.1 - 0.00026 20.2 0.1 0.00041 19.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 GAM23534.1 - 0.0051 16.7 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM23534.1 - 0.0067 17.2 0.0 0.012 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM23534.1 - 0.041 14.1 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Hexose_dehydrat PF03559.9 GAM23534.1 - 0.047 12.7 0.1 0.066 12.2 0.1 1.2 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase Arch_ATPase PF01637.13 GAM23534.1 - 0.057 13.1 0.8 0.69 9.5 0.6 2.0 1 1 0 1 1 1 0 Archaeal ATPase UPF0270 PF06794.7 GAM23534.1 - 0.077 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) AAA_28 PF13521.1 GAM23534.1 - 0.095 12.6 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 GAM23534.1 - 0.096 12.0 0.0 5 6.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 GAM23534.1 - 0.15 12.2 1.9 4 7.6 0.0 2.5 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CH PF00307.26 GAM23535.1 - 9.2e-30 102.8 0.2 2.1e-14 53.4 0.0 2.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM23535.1 - 1.6e-11 43.6 0.0 3.5e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 CAMSAP CH domain DUF1042 PF06294.6 GAM23535.1 - 0.0036 16.9 0.6 1.6 8.2 0.0 2.1 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1042) Lpp-LpqN PF10738.4 GAM23535.1 - 0.022 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN Metallophos PF00149.23 GAM23536.1 - 2.2e-06 27.2 0.1 3.9e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAP2 PF01569.16 GAM23537.1 - 6e-10 38.9 13.1 6.9e-10 38.6 4.5 2.5 2 0 0 2 2 2 2 PAP2 superfamily PAP2_3 PF14378.1 GAM23537.1 - 1.6e-08 34.3 2.5 1.6e-08 34.3 1.8 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 GAM23537.1 - 2.7 7.3 16.1 3.3 7.0 1.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Taxilin PF09728.4 GAM23539.1 - 1.6e-32 112.8 56.1 1.6e-32 112.8 38.9 1.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF869 PF05911.6 GAM23539.1 - 0.009 14.3 56.6 0.011 14.0 38.1 1.9 1 1 0 1 1 1 1 Plant protein of unknown function (DUF869) SlyX PF04102.7 GAM23539.1 - 0.022 15.1 0.7 0.022 15.1 0.5 5.7 3 3 2 5 5 5 0 SlyX WEMBL PF05701.6 GAM23539.1 - 0.32 9.4 52.1 2.7 6.3 26.3 2.9 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DivIVA PF05103.8 GAM23539.1 - 0.34 10.9 58.7 0.68 9.9 3.3 5.4 1 1 5 6 6 6 0 DivIVA protein GAS PF13851.1 GAM23539.1 - 0.53 9.4 63.0 0.15 11.2 6.2 4.2 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 GAM23539.1 - 2.2 7.7 59.0 2.4 7.6 15.4 3.3 1 1 2 3 3 3 0 Ezrin/radixin/moesin family SUKH-4 PF14435.1 GAM23539.1 - 3.5 7.2 6.6 1.1 8.9 0.2 2.7 3 0 0 3 3 3 0 SUKH-4 immunity protein Sec39 PF08314.6 GAM23540.1 - 8.7e-33 113.2 12.9 2.7e-30 105.0 8.9 3.4 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Nbas_N PF15492.1 GAM23540.1 - 1.1e-15 57.5 0.0 8.6e-15 54.5 0.0 2.2 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Actin PF00022.14 GAM23541.1 - 7.2e-119 396.7 0.0 8.9e-119 396.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM23541.1 - 0.077 13.3 0.0 0.24 11.8 0.0 1.8 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Kelch_6 PF13964.1 GAM23542.1 - 3.7e-05 23.7 1.2 0.0043 17.1 0.3 2.8 2 1 1 3 3 3 1 Kelch motif Kelch_3 PF13415.1 GAM23542.1 - 0.00012 22.1 0.1 0.14 12.4 0.0 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM23542.1 - 0.00032 20.3 1.7 0.21 11.3 0.2 2.5 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM23542.1 - 0.0091 15.5 0.2 0.029 13.9 0.0 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 GAM23542.1 - 0.01 15.7 0.2 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_2 PF07646.10 GAM23542.1 - 0.018 14.8 0.2 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 GAM23543.1 - 6.9e-13 48.1 6.1 0.0032 17.5 0.1 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM23543.1 - 8.8e-07 28.5 7.1 0.0029 17.3 0.1 5.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM23543.1 - 2.7e-06 27.1 1.0 0.0056 16.6 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 GAM23543.1 - 6.5e-06 25.6 5.7 0.036 13.6 0.1 4.3 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM23543.1 - 0.00012 22.1 0.3 1.9 8.7 0.0 4.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM23543.1 - 0.0049 16.5 0.3 0.31 10.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Baculo_p47 PF05112.7 GAM23543.1 - 0.35 10.2 5.7 0.64 9.3 3.9 1.3 1 0 0 1 1 1 0 Baculovirus P47 protein Kelch_6 PF13964.1 GAM23544.1 - 6.9e-12 45.0 4.3 0.00051 20.0 0.0 3.8 3 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM23544.1 - 6.6e-10 38.5 4.8 0.0023 17.6 0.0 3.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM23544.1 - 3.8e-09 36.4 0.5 0.0087 16.1 0.0 3.5 2 1 1 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM23544.1 - 1.3e-08 34.1 1.4 0.0013 18.2 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM23544.1 - 0.00092 19.1 4.2 0.025 14.5 0.2 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 GAM23544.1 - 0.0052 16.4 1.8 0.25 11.1 0.0 3.6 4 0 0 4 4 4 1 Kelch motif Cna_B PF05738.8 GAM23545.1 - 3.9e-26 90.5 27.6 0.0096 15.6 0.3 14.7 12 2 0 12 12 12 9 Cna protein B-type domain Y_Y_Y PF07495.8 GAM23545.1 - 3.9e-12 45.7 5.8 0.069 12.9 0.0 9.4 11 0 0 11 11 11 3 Y_Y_Y domain DUF2012 PF09430.5 GAM23545.1 - 8.1e-09 35.3 0.0 8.4 6.2 0.0 8.1 9 0 0 9 9 9 3 Protein of unknown function (DUF2012) TILa PF12714.2 GAM23545.1 - 4.6 7.0 16.2 6.3 6.6 0.2 3.6 3 0 0 3 3 3 0 TILa domain Cas_NE0113 PF09623.5 GAM23546.1 - 0.09 12.2 0.7 0.46 9.9 0.2 2.0 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) WD40 PF00400.27 GAM23547.1 - 6.8e-38 127.2 22.6 2.2e-08 33.6 0.1 7.2 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM23547.1 - 1e-07 30.4 16.3 0.0014 16.8 0.2 5.5 3 2 1 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 GAM23547.1 - 2.2e-07 30.4 1.7 1.4e-06 27.9 1.2 2.3 1 1 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 GAM23547.1 - 6.7e-07 28.4 0.4 0.0005 18.9 0.0 3.7 2 1 1 3 3 3 1 Nup133 N terminal like BBS2_Mid PF14783.1 GAM23547.1 - 6.9e-05 22.5 0.1 0.8 9.4 0.1 3.8 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region F-box PF00646.28 GAM23547.1 - 0.0015 18.1 9.3 0.0077 15.8 0.1 3.3 3 0 0 3 3 3 2 F-box domain PQQ_3 PF13570.1 GAM23547.1 - 0.016 15.4 0.0 18 5.7 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain SSP160 PF06933.6 GAM23547.1 - 0.052 11.5 11.1 0.076 10.9 7.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 F-box-like_2 PF13013.1 GAM23547.1 - 0.075 12.7 3.8 0.82 9.4 2.6 2.4 1 1 0 1 1 1 0 F-box-like domain CAF-1_p150 PF11600.3 GAM23547.1 - 2.4 7.4 6.5 3.8 6.8 4.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PH PF00169.24 GAM23548.1 - 2e-14 53.6 5.2 3.6e-12 46.3 0.0 2.6 2 1 0 2 2 2 2 PH domain PH_3 PF14593.1 GAM23548.1 - 1.1e-05 25.2 0.1 2.4e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM23548.1 - 4.3e-05 23.4 0.2 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 GAM23548.1 - 0.00014 22.0 0.8 0.00014 22.0 0.5 4.1 4 1 0 4 4 4 1 Pleckstrin homology domain Mcp5_PH PF12814.2 GAM23548.1 - 0.027 14.4 0.1 0.027 14.4 0.1 3.2 3 2 1 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 GAM23548.1 - 0.1 12.7 0.5 0.41 10.7 0.0 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain DUF2356 PF10189.4 GAM23549.1 - 3.8e-88 294.4 1.5 4.2e-88 294.2 0.2 1.7 2 0 0 2 2 2 1 Conserved protein (DUF2356) Lung_7-TM_R PF06814.8 GAM23550.1 - 5.5e-10 38.6 23.1 8.8e-10 38.0 16.0 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF3245 PF11595.3 GAM23550.1 - 3.2 8.0 6.7 5.1 7.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) TFIIF_alpha PF05793.7 GAM23550.1 - 4.5 5.5 9.6 6.4 5.0 6.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SNase PF00565.12 GAM23551.1 - 6.4e-57 190.4 1.6 3.4e-14 53.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 GAM23551.1 - 2.4e-13 49.9 0.0 5.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.7 GAM23551.1 - 0.15 12.1 0.7 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Agenet domain DUF4050 PF13259.1 GAM23552.1 - 0.00034 20.5 8.7 0.0025 17.7 6.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Paramyxo_C PF01692.13 GAM23552.1 - 0.033 13.8 3.5 0.035 13.7 2.4 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c PFEMP PF03011.10 GAM23552.1 - 0.11 12.8 2.6 0.15 12.3 1.8 1.1 1 0 0 1 1 1 0 PFEMP DBL domain GET2 PF08690.5 GAM23552.1 - 0.17 11.0 6.5 0.22 10.7 4.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 AKAP2_C PF15304.1 GAM23552.1 - 0.46 10.0 8.9 0.58 9.7 6.2 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Macoilin PF09726.4 GAM23552.1 - 1.1 7.4 14.9 1.2 7.3 10.3 1.0 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 GAM23552.1 - 1.6 7.2 12.6 1.8 7.0 8.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NST1 PF13945.1 GAM23552.1 - 1.9 8.5 11.3 2.3 8.2 7.8 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SSP160 PF06933.6 GAM23552.1 - 2.2 6.1 21.5 2.5 5.9 14.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sec10 PF07393.6 GAM23552.1 - 2.8 6.0 10.5 3.4 5.7 7.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Presenilin PF01080.12 GAM23552.1 - 3.5 6.3 8.9 3.9 6.2 6.1 1.0 1 0 0 1 1 1 0 Presenilin DUF3537 PF12056.3 GAM23552.1 - 5.8 5.5 6.3 6.7 5.3 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF515 PF04415.7 GAM23552.1 - 7.5 4.6 14.6 8.6 4.4 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Period_C PF12114.3 GAM23552.1 - 8 6.0 14.5 9.6 5.7 10.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region EF-hand_6 PF13405.1 GAM23553.1 - 2.5e-22 76.6 5.8 1e-05 24.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 GAM23553.1 - 3.9e-22 75.7 7.5 1.2e-05 24.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM23553.1 - 1.5e-21 76.2 6.1 6.1e-11 42.3 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM23553.1 - 9.2e-20 69.0 11.5 1.8e-06 27.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 GAM23553.1 - 3.7e-18 64.8 6.6 1.7e-05 24.3 0.3 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM23553.1 - 4.9e-07 29.7 0.5 0.022 14.7 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM23553.1 - 6.2e-06 25.7 5.1 1.1 8.9 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 GAM23553.1 - 0.00027 20.7 0.0 0.53 10.2 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 GAM23553.1 - 0.0015 18.2 1.9 0.066 12.9 0.0 2.9 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_2 PF09068.6 GAM23553.1 - 0.0038 17.2 0.0 4.4 7.3 0.0 2.8 3 1 0 3 3 3 2 EF hand Csm1 PF12539.3 GAM23553.1 - 0.0061 17.0 0.0 1.4 9.4 0.0 2.5 1 1 1 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF3164 PF11363.3 GAM23553.1 - 0.012 15.0 1.0 3.2 7.0 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3164) TerB PF05099.8 GAM23553.1 - 0.017 14.8 0.1 0.28 10.9 0.0 2.3 1 1 2 3 3 3 0 Tellurite resistance protein TerB EF-hand_3 PF09069.6 GAM23553.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand Poxvirus PF06227.7 GAM23553.1 - 0.13 11.8 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 dsDNA Poxvirus PROCN PF08083.6 GAM23554.1 - 8.7e-211 699.6 9.8 6.7e-141 469.4 2.2 2.4 2 0 0 2 2 2 2 PROCN (NUC071) domain PRP8_domainIV PF12134.3 GAM23554.1 - 2.3e-123 409.9 0.7 4e-123 409.1 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 GAM23554.1 - 3.2e-86 286.6 3.9 2.5e-57 192.7 0.2 2.7 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 GAM23554.1 - 6.3e-79 262.9 3.7 1.7e-78 261.5 2.6 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 GAM23554.1 - 8e-68 226.2 0.1 1.7e-67 225.2 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 GAM23554.1 - 6.8e-45 151.8 1.8 2e-44 150.3 0.5 2.3 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 GAM23554.1 - 8.4e-43 144.1 0.6 2.7e-42 142.5 0.4 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.11 GAM23554.1 - 1.1e-34 120.0 0.1 6.8e-33 114.2 0.4 2.8 3 0 0 3 3 3 1 Hom_end-associated Hint JAB PF01398.16 GAM23554.1 - 2.2e-09 37.0 0.0 6.1e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4423 PF14394.1 GAM23554.1 - 1.5e-05 24.5 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) WD40 PF00400.27 GAM23555.1 - 7.2e-22 76.4 15.1 7.2e-06 25.6 0.2 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 GAM23555.1 - 4e-07 28.5 6.2 0.029 12.5 0.9 3.6 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM23555.1 - 0.00022 20.0 5.1 0.6 8.7 0.1 3.6 1 1 2 4 4 4 3 Nup133 N terminal like BBS2_Mid PF14783.1 GAM23555.1 - 0.047 13.4 0.5 4.6 7.0 0.0 3.2 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region LRAT PF04970.8 GAM23555.1 - 0.084 12.8 1.2 0.41 10.6 0.2 2.1 2 0 0 2 2 2 0 Lecithin retinol acyltransferase eIF3g PF12353.3 GAM23556.1 - 3.8e-24 85.0 7.5 9.4e-24 83.7 5.2 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 GAM23556.1 - 5.3e-20 70.8 0.0 1.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM23556.1 - 7.1e-15 54.7 0.1 2e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM23556.1 - 4.2e-10 39.3 0.0 8.9e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM23556.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MCP_N PF05581.7 GAM23557.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Vibrio chemotaxis protein N terminus GET2 PF08690.5 GAM23558.1 - 5.2 6.2 8.1 7.7 5.6 5.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Rhodanese PF00581.15 GAM23559.1 - 3.1e-32 111.2 0.0 1e-17 64.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF4034 PF13226.1 GAM23559.1 - 0.0087 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4034) NLPC_P60 PF00877.14 GAM23560.1 - 4.4 7.1 12.3 19 5.1 8.5 2.1 1 1 0 1 1 1 0 NlpC/P60 family PAT1 PF09770.4 GAM23561.1 - 0.94 7.6 32.6 1.3 7.1 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PA26 PF04636.8 GAM23562.1 - 0.0054 15.4 0.2 0.0054 15.4 0.2 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) EF-hand_1 PF00036.27 GAM23563.1 - 0.0054 15.9 0.0 0.0054 15.9 0.0 2.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 GAM23563.1 - 0.0075 15.5 0.1 0.021 14.1 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 GAM23563.1 - 0.0099 15.9 0.1 0.031 14.3 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM23563.1 - 0.1 12.2 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain pair DUF3439 PF11921.3 GAM23563.1 - 1.5 8.6 8.9 3.4 7.4 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SR-25 PF10500.4 GAM23563.1 - 5.7 6.3 9.2 12 5.2 6.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Notch PF00066.12 GAM23564.1 - 1.8e-17 63.3 34.0 2.7e-09 37.1 8.8 2.5 2 0 0 2 2 2 2 LNR domain DUF3184 PF11380.3 GAM23564.1 - 7.4e-09 34.1 0.0 0.00019 19.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) MSP1_C PF07462.6 GAM23564.1 - 0.24 9.7 2.9 0.35 9.2 2.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Vanabin-2 PF11437.3 GAM23564.1 - 2.2 8.2 10.8 3.6 7.6 1.7 2.5 1 1 1 2 2 2 0 Vanadium-binding protein 2 Pyr_redox_2 PF07992.9 GAM23565.1 - 3.3e-20 72.8 0.0 1.8e-19 70.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM23565.1 - 2.2e-17 63.2 3.4 3e-12 46.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM23565.1 - 4.6e-07 29.7 0.1 3.5e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM23565.1 - 5.4e-07 29.8 0.0 0.048 13.7 0.0 2.5 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM23565.1 - 5.2e-06 25.5 4.2 8.2e-05 21.6 0.1 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM23565.1 - 9.8e-06 24.4 0.2 0.00074 18.2 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.1 GAM23565.1 - 1.6e-05 25.0 0.9 0.1 12.8 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.1 GAM23565.1 - 2.5e-05 23.3 0.0 0.0046 15.9 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 GAM23565.1 - 9.9e-05 21.5 1.9 0.0053 15.8 0.0 2.7 2 1 1 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 GAM23565.1 - 0.00015 20.7 0.9 0.00035 19.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 GAM23565.1 - 0.00017 21.0 1.6 0.15 11.3 0.2 2.7 2 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 GAM23565.1 - 0.00019 20.5 0.2 0.022 13.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 GAM23565.1 - 0.00026 19.9 0.3 0.39 9.5 0.0 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A HI0933_like PF03486.9 GAM23565.1 - 0.0022 16.5 4.1 0.018 13.5 0.1 2.8 4 0 0 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.16 GAM23565.1 - 0.011 15.3 0.5 0.73 9.3 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAM23565.1 - 0.012 14.5 0.0 3.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 GAM23565.1 - 0.013 15.4 1.1 1.2 9.1 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 GAM23565.1 - 0.014 15.1 1.3 2.5 7.8 0.1 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding Phage_30_8 PF06019.6 GAM23565.1 - 0.052 13.2 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Phage GP30.8 protein FAD_oxidored PF12831.2 GAM23565.1 - 0.058 12.4 0.8 0.086 11.8 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3115 PF11312.3 GAM23565.1 - 0.16 10.8 0.2 15 4.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3115) Amino_oxidase PF01593.19 GAM23565.1 - 0.16 11.0 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 GAM23566.1 - 1.5e-24 87.0 0.0 4.5e-24 85.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM23566.1 - 2.2e-18 66.4 0.8 1.6e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM23566.1 - 6.3e-09 35.3 0.1 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 GAM23566.1 - 1.2e-07 30.9 0.7 0.0082 15.0 0.1 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM23566.1 - 4.1e-07 29.9 0.2 0.0019 18.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM23566.1 - 6.8e-07 28.5 0.1 0.0001 21.3 0.0 2.5 1 1 2 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 GAM23566.1 - 2.5e-06 27.6 0.2 0.00077 19.5 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 GAM23566.1 - 6.4e-06 25.3 0.0 0.068 12.0 0.0 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 GAM23566.1 - 8.7e-06 24.4 0.8 0.28 9.6 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Trp_halogenase PF04820.9 GAM23566.1 - 3.7e-05 22.5 0.3 0.075 11.6 0.0 2.6 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.13 GAM23566.1 - 7.9e-05 22.6 1.2 0.99 9.4 0.1 3.3 3 0 0 3 3 3 2 TrkA-N domain NAD_binding_9 PF13454.1 GAM23566.1 - 8e-05 22.4 1.1 2 8.1 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 GAM23566.1 - 8.1e-05 22.8 0.9 0.22 11.8 0.0 2.7 2 1 0 2 2 2 2 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 GAM23566.1 - 0.0021 18.3 1.8 3.5 7.9 0.1 3.8 3 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 GAM23566.1 - 0.003 16.6 0.1 0.59 9.1 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 GAM23566.1 - 0.0031 16.4 1.1 0.13 11.0 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain DUF1188 PF06690.6 GAM23566.1 - 0.042 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Zeta_toxin PF06414.7 GAM23566.1 - 0.045 12.8 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Saccharop_dh PF03435.13 GAM23566.1 - 0.062 12.2 1.0 3.9 6.3 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF812 PF05667.6 GAM23567.1 - 1.7e-166 555.2 25.6 2.6e-166 554.6 17.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Occludin_ELL PF07303.8 GAM23567.1 - 2.8 8.7 34.6 0.039 14.6 2.3 4.6 1 1 4 5 5 5 0 Occludin homology domain IncA PF04156.9 GAM23567.1 - 5.2 6.6 46.7 4.3 6.8 24.6 3.8 2 1 1 3 3 3 0 IncA protein 5TM-5TMR_LYT PF07694.7 GAM23569.1 - 0.029 13.7 1.2 0.056 12.7 0.8 1.6 1 1 0 1 1 1 0 5TMR of 5TMR-LYT FMN_dh PF01070.13 GAM23570.1 - 7.4e-132 439.5 0.0 8.9e-132 439.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 GAM23570.1 - 1.9e-07 30.4 2.0 0.00043 19.4 0.1 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 GAM23570.1 - 3e-07 29.6 1.6 6.2e-07 28.6 0.3 2.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 GAM23570.1 - 3.3e-07 29.7 1.1 5.4e-07 29.0 0.8 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 GAM23570.1 - 4e-05 22.6 0.1 7.8e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 GAM23570.1 - 0.0001 21.6 0.7 0.0051 16.1 0.0 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 GAM23570.1 - 0.00027 19.8 0.4 0.0031 16.4 0.3 2.4 2 1 1 3 3 3 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 GAM23570.1 - 0.0011 18.0 0.1 0.0087 15.0 0.0 2.3 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase DHDPS PF00701.17 GAM23570.1 - 0.082 11.4 0.0 0.35 9.4 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family TMP-TENI PF02581.12 GAM23570.1 - 0.091 11.8 0.1 0.87 8.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI tRNA-synt_2 PF00152.15 GAM23571.1 - 4.9e-87 291.8 0.0 7.3e-87 291.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM23571.1 - 6.8e-09 35.4 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAM23571.1 - 2.3e-06 26.9 0.0 0.0038 16.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAM23571.1 - 0.034 13.7 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) GST_N PF02798.15 GAM23572.1 - 3.6e-10 39.8 0.0 7.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM23572.1 - 6.3e-08 32.5 0.0 2.3e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM23572.1 - 4e-07 30.4 0.0 6.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM23572.1 - 3.9e-06 26.6 0.0 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM23572.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HSP20 PF00011.16 GAM23573.1 - 0.004 16.9 0.4 0.027 14.3 0.0 2.4 2 1 0 2 2 2 1 Hsp20/alpha crystallin family PAT1 PF09770.4 GAM23573.1 - 0.0087 14.3 30.2 0.01 14.1 20.9 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 GAM23573.1 - 0.017 15.4 11.1 0.023 14.9 7.7 1.3 1 0 0 1 1 1 0 AAA domain VID27 PF08553.5 GAM23573.1 - 0.019 13.2 4.8 0.022 13.0 3.3 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FliP PF00813.15 GAM23573.1 - 0.034 13.8 4.7 0.051 13.2 3.3 1.2 1 0 0 1 1 1 0 FliP family Suf PF05843.9 GAM23573.1 - 0.035 13.8 10.7 0.044 13.5 7.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF3_subunit PF08597.5 GAM23573.1 - 0.072 12.6 12.8 0.1 12.1 8.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.7 GAM23573.1 - 0.12 12.2 7.8 0.15 11.8 5.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 GAM23573.1 - 0.22 9.7 9.4 0.27 9.4 6.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.11 GAM23573.1 - 0.96 9.2 5.4 1.3 8.8 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S15 PF02129.13 GAM23573.1 - 1.8 7.9 9.6 2.5 7.4 6.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Sec62 PF03839.11 GAM23573.1 - 2 7.7 9.6 2.8 7.2 6.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3276 PF11680.3 GAM23573.1 - 3 7.6 9.9 5.1 6.9 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Gti1_Pac2 PF09729.4 GAM23573.1 - 4.9 6.9 10.8 8 6.2 7.5 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.1 GAM23573.1 - 5 6.8 9.6 7.2 6.2 6.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RED_N PF07808.8 GAM23573.1 - 6.1 5.9 18.1 9.8 5.3 12.6 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Ctr PF04145.10 GAM23573.1 - 6.2 6.8 6.6 9.8 6.2 4.6 1.3 1 0 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.8 GAM23573.1 - 7.6 6.3 27.8 11 5.8 19.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OmpH PF03938.9 GAM23573.1 - 9.6 6.1 34.2 16 5.3 23.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 GAM23575.1 - 6.3e-48 163.1 1.1 4e-42 144.1 0.4 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23575.1 - 1.3e-37 129.2 0.8 6.1e-34 117.2 0.3 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM23575.1 - 0.058 12.3 0.1 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 GAM23575.1 - 0.085 12.5 0.0 9.8 5.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myosin_head PF00063.16 GAM23577.1 - 5.2e-210 699.0 0.4 9.2e-170 566.0 0.4 2.5 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.1 GAM23577.1 - 0.0048 16.8 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 GAM23577.1 - 0.008 15.9 0.1 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 GAM23577.1 - 0.0082 16.2 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 GAM23577.1 - 0.08 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 GAM23577.1 - 0.099 11.5 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 GAM23577.1 - 0.1 12.9 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 GAM23577.1 - 0.16 11.0 0.0 0.58 9.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Pkinase_Tyr PF07714.12 GAM23578.1 - 5e-52 176.5 0.0 8.8e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23578.1 - 2.1e-46 158.2 0.0 4e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Miro PF08477.8 GAM23578.1 - 6.7e-16 58.8 0.0 1.6e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM23578.1 - 4.2e-13 48.9 0.1 8.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Ras family LRR_4 PF12799.2 GAM23578.1 - 5.5e-08 32.2 2.5 0.00019 20.9 1.5 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Arf PF00025.16 GAM23578.1 - 1.4e-06 27.6 0.1 2.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_8 PF13855.1 GAM23578.1 - 1.2e-05 24.9 0.9 3.8e-05 23.3 0.6 1.9 1 0 0 1 1 1 1 Leucine rich repeat Gtr1_RagA PF04670.7 GAM23578.1 - 0.00087 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM23578.1 - 0.0014 18.5 0.0 0.0054 16.6 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 GAM23578.1 - 0.0063 16.8 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter LRR_1 PF00560.28 GAM23578.1 - 0.007 16.2 1.1 6.6 7.1 0.0 4.3 3 0 0 3 3 3 1 Leucine Rich Repeat PduV-EutP PF10662.4 GAM23578.1 - 0.0093 15.4 0.1 0.046 13.2 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 GAM23578.1 - 0.022 13.9 0.2 0.063 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 GAM23578.1 - 0.064 12.9 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_C39_2 PF13529.1 GAM23579.1 - 1.5e-10 41.6 0.0 4.1e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase_C39 like family Guanylate_cyc_2 PF09778.4 GAM23579.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Guanylylate cyclase Transpep_BrtH PF14399.1 GAM23579.1 - 0.062 12.5 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Gar1 PF04410.9 GAM23580.1 - 5.2e-17 61.7 0.5 5.2e-17 61.7 0.4 2.6 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region SH3BGR PF04908.10 GAM23581.1 - 1.9e-15 56.5 0.1 2.8e-15 56.0 0.1 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 GAM23581.1 - 1.2e-10 41.2 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 GAM23581.1 - 0.075 13.2 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RhoGAP PF00620.22 GAM23582.1 - 5.2e-36 123.5 0.3 1.4e-35 122.1 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.13 GAM23582.1 - 3.9e-09 36.3 6.5 8e-09 35.3 4.5 1.5 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 GAM23582.1 - 4.9e-05 22.3 9.7 5.9e-05 22.1 6.1 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GAS PF13851.1 GAM23582.1 - 0.0047 16.1 3.3 0.0047 16.1 2.3 3.2 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding IncA PF04156.9 GAM23582.1 - 0.91 9.0 7.9 0.48 9.9 1.6 2.4 2 0 0 2 2 2 0 IncA protein DSPc PF00782.15 GAM23583.1 - 5.5e-12 45.4 5.9 3e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain tRNA-synt_1 PF00133.17 GAM23584.1 - 1.3e-12 46.5 0.0 1.6e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAM23584.1 - 2e-10 39.9 0.0 2.5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM23585.1 - 1.1e-36 126.0 0.0 2.7e-36 124.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM23585.1 - 6.8e-13 48.6 0.6 4.4e-12 46.0 0.4 2.2 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM23585.1 - 6e-11 41.6 0.2 4.7e-08 32.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAM23585.1 - 6.6e-06 25.4 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 GAM23585.1 - 0.028 13.1 0.1 0.63 8.6 0.0 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (K) PhyH PF05721.8 GAM23586.1 - 2.6e-07 30.8 0.0 6.7e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM23586.1 - 0.00038 19.0 0.4 2.5 6.4 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) NIF PF03031.13 GAM23587.1 - 2.1e-23 82.7 1.1 4.3e-23 81.7 0.7 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 GAM23587.1 - 8e-06 25.1 0.0 1.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF1938 PF09153.5 GAM23587.1 - 0.1 12.4 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Mucin PF01456.12 GAM23587.1 - 0.24 11.1 17.4 0.36 10.6 12.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Arf PF00025.16 GAM23588.1 - 1.8e-77 258.4 0.1 2.2e-77 258.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM23588.1 - 1.3e-14 53.7 0.0 1.6e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM23588.1 - 1.9e-12 46.8 0.0 2.2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM23588.1 - 3.4e-12 45.7 2.7 1.6e-09 36.9 0.5 2.4 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM23588.1 - 7.3e-12 44.9 0.0 8.5e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM23588.1 - 4.9e-08 33.4 0.0 8.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM23588.1 - 1.7e-05 24.7 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAM23588.1 - 0.0056 15.7 0.5 0.018 14.1 0.4 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 GAM23588.1 - 0.011 15.1 0.3 0.061 12.7 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAM23588.1 - 0.087 12.7 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM23588.1 - 0.18 11.4 0.7 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Pkinase_Tyr PF07714.12 GAM23589.1 - 5.1e-59 199.4 0.0 7.5e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23589.1 - 5.2e-53 179.8 0.0 7.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM23589.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.9 GAM23589.1 - 0.00025 21.0 0.1 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain APH PF01636.18 GAM23589.1 - 0.016 14.9 0.2 0.2 11.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3439 PF11921.3 GAM23589.1 - 0.053 13.2 2.1 0.12 12.1 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM23589.1 - 0.12 10.3 6.3 0.17 9.8 4.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_5 PF12695.2 GAM23591.1 - 3.9e-17 62.3 0.0 5.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM23591.1 - 6e-14 52.4 0.0 8.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM23591.1 - 1.2e-07 31.1 0.0 0.0054 15.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAM23591.1 - 3e-05 23.5 0.6 0.0025 17.2 0.0 2.8 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 GAM23591.1 - 0.00082 18.3 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 GAM23591.1 - 0.0019 17.7 0.2 2 7.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 GAM23591.1 - 0.0032 16.7 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family PAE PF03283.8 GAM23591.1 - 0.012 14.2 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_S15 PF02129.13 GAM23591.1 - 0.016 14.6 0.0 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 GAM23591.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2974 PF11187.3 GAM23591.1 - 0.06 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.7 GAM23591.1 - 0.072 11.5 0.1 1.9 6.9 0.0 2.6 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 GAM23591.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pterin_4a PF01329.14 GAM23592.1 - 3.5e-23 81.1 0.3 6.9e-23 80.2 0.0 1.5 2 0 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase LST1 PF05083.8 GAM23592.1 - 0.023 14.6 0.2 0.045 13.7 0.1 1.6 1 1 0 1 1 1 0 LST-1 protein DUF1566 PF07603.6 GAM23592.1 - 0.13 11.9 1.5 0.19 11.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1566) Cullin PF00888.17 GAM23593.1 - 7.2e-121 404.5 24.7 7.2e-121 404.5 17.1 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 GAM23593.1 - 2.5e-26 91.2 2.6 6.2e-26 90.0 1.8 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS PF00615.14 GAM23593.1 - 0.035 14.2 9.5 0.51 10.4 1.9 3.7 3 1 0 3 3 3 0 Regulator of G protein signaling domain GAT PF03127.9 GAM23593.1 - 0.39 10.7 6.1 1.3 9.0 0.0 3.8 3 1 1 4 4 4 0 GAT domain TIG PF01833.19 GAM23594.1 - 8.5e-14 51.3 32.3 3e-06 27.1 1.2 4.9 5 0 0 5 5 5 3 IPT/TIG domain LRR_4 PF12799.2 GAM23594.1 - 0.016 14.7 1.1 0.016 14.7 0.8 4.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF2771 PF10969.3 GAM23594.1 - 0.023 14.0 2.3 0.37 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2771) SKG6 PF08693.5 GAM23594.1 - 0.029 13.6 1.2 0.073 12.3 0.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_8 PF13855.1 GAM23594.1 - 0.68 9.7 10.9 0.037 13.7 1.6 3.4 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 GAM23594.1 - 3.3 8.0 8.5 25 5.4 0.3 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat Peptidase_M16_C PF05193.16 GAM23595.1 - 3.4e-12 46.4 0.1 1.8e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM23595.1 - 1.9e-08 34.1 0.0 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Fe-S_biosyn PF01521.15 GAM23596.1 - 2.3e-15 56.4 0.3 2.6e-15 56.3 0.2 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Adhesin_Dr PF04619.7 GAM23596.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Dr-family adhesin LRR_4 PF12799.2 GAM23598.1 - 1.1e-28 98.2 33.9 9.6e-07 28.2 0.2 5.4 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM23598.1 - 2e-18 65.8 77.9 1.3e-06 28.0 6.1 4.9 1 1 5 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 GAM23598.1 - 4.8e-15 55.5 15.5 5.5e-08 32.5 1.2 3.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 GAM23598.1 - 3.4e-08 32.4 25.8 3.8 7.9 0.0 9.3 8 1 1 9 9 9 4 Leucine Rich Repeat LRR_7 PF13504.1 GAM23598.1 - 3.5e-06 26.3 17.8 14 6.4 0.0 8.9 8 1 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 GAM23598.1 - 0.0016 18.2 28.7 3.2 8.0 0.0 9.2 6 3 3 9 9 9 2 Leucine Rich repeat Abhydrolase_1 PF00561.15 GAM23599.1 - 2.9e-25 89.1 0.0 9.6e-24 84.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM23599.1 - 3.5e-19 69.6 0.0 4.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM23599.1 - 1.9e-12 47.1 0.0 8.7e-12 45.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 GAM23599.1 - 0.00024 20.9 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 GAM23599.1 - 0.009 15.2 0.0 1.9 7.6 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 GAM23599.1 - 0.072 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Hydrolase_4 PF12146.3 GAM23599.1 - 0.095 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase HSP70 PF00012.15 GAM23600.1 - 1.6e-271 901.5 8.9 1.8e-271 901.3 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM23600.1 - 5.1e-15 54.8 0.2 1.8e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 GAM23600.1 - 0.0021 17.7 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 GAM23600.1 - 0.0026 16.6 0.2 0.023 13.5 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Pex19 PF04614.7 GAM23600.1 - 0.0066 16.0 5.1 0.012 15.2 3.5 1.3 1 0 0 1 1 1 1 Pex19 protein family BcrAD_BadFG PF01869.15 GAM23600.1 - 0.053 12.8 0.4 9.4 5.4 0.0 2.7 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 GAM23600.1 - 0.078 12.0 2.1 0.14 11.2 0.0 2.3 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase Anoctamin PF04547.7 GAM23601.1 - 4.8e-17 61.7 17.1 6e-16 58.1 6.9 2.9 2 1 0 2 2 2 2 Calcium-activated chloride channel TMC PF07810.8 GAM23601.1 - 1e-08 35.5 2.1 1.3e-08 35.1 0.0 2.3 2 1 1 3 3 3 1 TMC domain DUF221 PF02714.10 GAM23601.1 - 0.00045 19.1 16.7 0.0054 15.6 11.6 2.4 1 1 0 1 1 1 1 Domain of unknown function DUF221 RRM_1 PF00076.17 GAM23602.1 - 1.6e-82 271.0 0.2 7.1e-22 76.8 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM23602.1 - 6.2e-59 195.9 0.1 2.7e-15 56.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM23602.1 - 6.9e-44 147.5 0.0 5.6e-11 42.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 GAM23602.1 - 6.4e-19 67.4 0.8 5.5e-18 64.4 0.4 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 GAM23602.1 - 7.9e-08 31.9 0.0 0.54 10.0 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 GAM23602.1 - 2.6e-07 30.3 0.0 0.015 14.9 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 GAM23602.1 - 4.1e-05 23.3 0.2 0.74 9.6 0.0 4.0 4 1 0 4 4 4 2 RNA binding motif OB_RNB PF08206.6 GAM23602.1 - 0.0088 15.5 1.2 15 5.2 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 GAM23602.1 - 0.01 15.5 1.9 6.3 6.6 0.0 4.1 4 1 0 4 4 4 0 Limkain b1 DUF4523 PF15023.1 GAM23602.1 - 0.03 13.8 0.0 4.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) CSD PF00313.17 GAM23602.1 - 0.21 11.3 1.4 14 5.5 0.0 3.0 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain RNA12 PF10443.4 GAM23603.1 - 3.4e-14 52.2 0.4 8.7e-10 37.6 0.3 2.5 2 1 0 2 2 2 2 RNA12 protein Arch_ATPase PF01637.13 GAM23603.1 - 0.00017 21.3 0.4 0.0027 17.4 0.0 2.8 3 1 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 GAM23603.1 - 0.00055 20.0 0.0 0.002 18.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 GAM23603.1 - 0.0053 16.9 3.8 0.95 9.6 0.0 3.6 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM23603.1 - 0.0054 16.7 0.2 0.23 11.4 0.0 2.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 GAM23603.1 - 0.014 15.2 0.6 0.17 11.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain DNA_pol3_theta PF06440.6 GAM23603.1 - 0.019 14.5 0.1 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III, theta subunit DUF904 PF06005.7 GAM23603.1 - 0.028 14.6 3.6 0.1 12.8 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF904) M PF02370.11 GAM23603.1 - 0.037 14.3 1.1 0.11 12.8 0.8 1.9 1 0 0 1 1 1 0 M protein repeat Peptidase_S10 PF00450.17 GAM23603.1 - 0.097 11.8 1.1 0.37 9.9 0.1 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase AAA_19 PF13245.1 GAM23603.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 GAM23603.1 - 0.18 12.6 2.1 1 10.1 0.0 2.8 2 2 0 2 2 2 0 AAA domain OmpH PF03938.9 GAM23603.1 - 1.7 8.5 6.3 4.6 7.1 4.4 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) eIF3_N PF09440.5 GAM23604.1 - 4.9e-11 42.9 4.7 1.8e-09 37.8 0.8 2.7 1 1 1 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 GAM23604.1 - 3.1e-09 37.0 0.9 9.2e-09 35.5 0.1 2.1 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 GAM23604.1 - 0.0014 18.9 2.3 0.35 11.2 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM23604.1 - 0.0047 17.5 0.6 1.9 9.2 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM23604.1 - 0.016 14.9 1.1 3.1 7.8 0.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NUDE_C PF04880.8 GAM23604.1 - 0.024 15.0 0.5 0.047 14.0 0.4 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TPR_2 PF07719.12 GAM23604.1 - 0.31 11.0 2.2 4.3 7.5 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM23604.1 - 0.51 10.9 5.2 1.1 9.9 0.8 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 GAM23604.1 - 1.3 9.2 4.8 11 6.2 0.4 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat MSA-2c PF12238.3 GAM23604.1 - 3.9 7.0 7.2 1.2 8.7 1.1 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Arf PF00025.16 GAM23605.1 - 4.6e-40 136.7 0.0 1.5e-39 135.0 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM23605.1 - 2.4e-10 40.0 0.0 2.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23605.1 - 3.9e-10 40.2 0.0 6.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM23605.1 - 2.8e-08 33.2 0.0 3.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM23605.1 - 6.8e-08 31.5 3.1 7e-05 21.6 0.3 2.8 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAM23605.1 - 1.8e-07 30.5 0.0 2.6e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM23605.1 - 0.0013 18.7 0.1 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase B_lectin PF01453.19 GAM23606.1 - 3.6e-44 149.2 8.0 8.2e-14 51.4 0.1 4.0 2 2 2 4 4 4 4 D-mannose binding lectin IN_DBD_C PF00552.16 GAM23606.1 - 0.0027 17.1 0.0 1 8.8 0.0 3.0 2 2 0 2 2 2 2 Integrase DNA binding domain AbrB-like PF14250.1 GAM23606.1 - 0.017 15.0 1.8 1.3 9.0 0.0 3.7 2 2 3 5 5 5 0 AbrB-like transcriptional regulator PQQ_2 PF13360.1 GAM23606.1 - 0.027 13.9 0.0 0.19 11.1 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain RNA_lig_T4_1 PF09511.5 GAM23606.1 - 0.15 11.4 0.0 4.3 6.7 0.0 2.8 1 1 0 1 1 1 0 RNA ligase DAO PF01266.19 GAM23607.1 - 2.5e-28 99.0 0.0 1.2e-27 96.8 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase AAA_23 PF13476.1 GAM23608.1 - 5.5e-15 56.2 0.0 5.5e-15 56.2 0.0 3.5 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.14 GAM23608.1 - 1.6e-10 40.5 8.0 6.8e-10 38.5 5.6 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Metallophos_2 PF12850.2 GAM23608.1 - 2.1e-06 27.6 0.4 2.7e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain AAA_21 PF13304.1 GAM23608.1 - 0.0019 18.1 0.9 0.0078 16.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain Metallophos PF00149.23 GAM23608.1 - 0.0063 15.9 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MMR_HSR1 PF01926.18 GAM23608.1 - 0.011 15.6 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM23608.1 - 0.018 14.5 0.0 0.072 12.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM23608.1 - 4.4 7.6 15.3 2.9 8.2 0.1 4.1 3 1 0 3 3 3 0 ABC transporter HTH_3 PF01381.17 GAM23609.1 - 2.7e-14 52.7 0.1 4.6e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 GAM23609.1 - 2.1e-08 34.1 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 GAM23609.1 - 1.6e-05 24.9 0.0 4e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain MBF1 PF08523.5 GAM23609.1 - 0.0069 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_37 PF13744.1 GAM23609.1 - 0.03 14.1 0.2 0.045 13.5 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L15e PF00827.12 GAM23610.1 - 7.3e-93 309.4 6.2 8.7e-93 309.1 4.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF2117 PF09890.4 GAM23610.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) DPM2 PF07297.7 GAM23611.1 - 9.3e-29 99.5 3.9 1e-28 99.4 2.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) ATG22 PF11700.3 GAM23611.1 - 0.089 11.2 1.7 0.1 11.0 1.2 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Ndc1_Nup PF09531.5 GAM23611.1 - 0.37 9.1 3.1 0.38 9.1 2.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIG-P PF08510.7 GAM23611.1 - 0.51 9.9 4.4 0.59 9.7 3.1 1.1 1 0 0 1 1 1 0 PIG-P PH PF00169.24 GAM23612.1 - 5e-14 52.3 0.1 1.1e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM23612.1 - 8e-08 32.5 1.2 8.9e-05 22.7 0.5 2.5 2 1 1 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 GAM23612.1 - 3.4e-06 26.8 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 PH domain HMA PF00403.21 GAM23612.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain PH_8 PF15409.1 GAM23612.1 - 0.00082 19.3 0.1 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 GAM23612.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Imm16 PF15565.1 GAM23613.1 - 0.19 11.5 0.1 0.42 10.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 16 FNIP PF05725.7 GAM23615.1 - 6.3e-60 198.8 0.4 3.4e-09 36.4 0.1 8.3 5 2 2 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 GAM23615.1 - 0.0035 17.2 1.2 11 6.0 0.0 4.8 4 3 1 5 5 5 2 Protein of unknown function (DUF1769) Asparaginase PF00710.15 GAM23616.1 - 1.2e-108 362.7 0.0 1.5e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Asparaginase tRNA-synt_1c PF00749.16 GAM23617.1 - 2e-95 319.0 0.0 2.6e-95 318.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PHP PF02811.14 GAM23618.1 - 1.2e-14 54.5 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 PHP domain TFIIA_gamma_C PF02751.9 GAM23620.1 - 1.8e-25 88.4 2.5 2.6e-25 87.9 1.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 GAM23620.1 - 9.8e-23 79.4 0.8 1.3e-22 79.0 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Ist1 PF03398.9 GAM23623.1 - 1e-47 161.6 3.8 1.3e-47 161.2 2.6 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Gag_p19 PF02228.11 GAM23623.1 - 0.059 13.6 0.3 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Major core protein p19 ABC_tran PF00005.22 GAM23624.1 - 2.2e-56 189.9 0.2 1.1e-26 93.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 GAM23624.1 - 2.2e-28 100.0 1.9 1.1e-13 51.8 0.1 4.4 2 2 1 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 GAM23624.1 - 2.2e-11 43.4 11.6 2.4e-11 43.2 1.2 2.7 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 GAM23624.1 - 3.4e-10 39.5 3.6 0.00014 21.1 0.1 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM23624.1 - 2.2e-08 33.5 1.6 0.0014 18.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM23624.1 - 1.3e-07 31.7 0.1 0.011 15.7 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 GAM23624.1 - 4.1e-07 30.3 3.3 0.0054 17.0 0.1 3.5 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 GAM23624.1 - 5.2e-07 29.5 4.4 0.32 10.9 0.0 4.5 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 GAM23624.1 - 6.8e-07 28.6 1.6 0.46 9.4 0.2 4.1 4 0 0 4 4 4 3 AAA ATPase domain AAA_25 PF13481.1 GAM23624.1 - 1.2e-05 24.8 0.0 0.51 9.7 0.0 4.1 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 GAM23624.1 - 1.3e-05 25.1 0.4 0.026 14.4 0.1 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 GAM23624.1 - 1.5e-05 25.8 7.6 0.15 12.8 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 GAM23624.1 - 4.8e-05 23.7 4.7 0.00038 20.8 0.4 3.9 3 1 1 4 4 4 2 AAA domain MobB PF03205.9 GAM23624.1 - 5.5e-05 22.8 0.1 0.09 12.4 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAM23624.1 - 6.7e-05 22.1 0.7 0.2 10.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_13 PF13166.1 GAM23624.1 - 0.00015 20.4 4.9 1.6 7.0 0.7 3.7 2 2 1 3 3 3 2 AAA domain AAA_10 PF12846.2 GAM23624.1 - 0.00016 21.2 3.1 0.28 10.5 0.2 2.9 2 1 1 3 3 3 2 AAA-like domain NACHT PF05729.7 GAM23624.1 - 0.00016 21.3 0.4 0.62 9.6 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_33 PF13671.1 GAM23624.1 - 0.00017 21.4 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM23624.1 - 0.00042 20.2 0.0 1.2 9.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain Miro PF08477.8 GAM23624.1 - 0.0007 20.0 0.0 0.84 10.1 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 GAM23624.1 - 0.00076 19.3 2.2 0.33 10.7 0.1 4.0 4 0 0 4 4 4 1 Domain of unknown function DUF87 ArgK PF03308.11 GAM23624.1 - 0.00094 18.0 0.1 0.99 8.1 0.0 2.4 2 0 0 2 2 2 2 ArgK protein G-alpha PF00503.15 GAM23624.1 - 0.00098 17.9 0.1 0.07 11.8 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 GAM23624.1 - 0.0012 18.9 3.8 0.46 10.6 0.2 3.7 2 2 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM23624.1 - 0.0014 18.6 0.5 0.46 10.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM23624.1 - 0.0022 18.1 0.1 1.6 8.9 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 GAM23624.1 - 0.0023 16.8 0.0 0.67 8.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.18 GAM23624.1 - 0.0028 17.4 0.1 0.25 11.1 0.0 2.8 2 1 0 2 2 2 1 Dynamin family RNA_helicase PF00910.17 GAM23624.1 - 0.0029 17.7 0.1 4 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 GAM23624.1 - 0.0056 16.4 0.5 0.87 9.2 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase NTPase_1 PF03266.10 GAM23624.1 - 0.022 14.4 0.3 4.4 6.9 0.0 3.8 3 1 0 3 3 3 0 NTPase DUF815 PF05673.8 GAM23624.1 - 0.031 13.2 0.1 0.73 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAM23624.1 - 0.056 13.1 0.1 13 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 GAM23624.1 - 0.059 12.8 0.7 6.7 6.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 GAM23624.1 - 0.11 11.9 0.1 9.3 5.5 0.0 2.2 2 0 0 2 2 2 0 MutS domain V PduV-EutP PF10662.4 GAM23624.1 - 0.12 11.9 0.1 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 GAM23624.1 - 0.13 11.9 0.1 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Adeno_IVa2 PF02456.10 GAM23624.1 - 0.14 10.8 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein Gtr1_RagA PF04670.7 GAM23624.1 - 0.17 10.9 0.7 9.9 5.2 0.0 2.7 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.9 GAM23624.1 - 0.22 10.4 4.8 2.2 7.1 0.0 2.8 4 1 0 4 4 3 0 KAP family P-loop domain Nup160 PF11715.3 GAM23625.1 - 2e-41 141.7 3.8 3.6e-41 140.9 2.6 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CcmE PF03100.10 GAM23625.1 - 1.9e-08 33.9 0.0 4.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 CcmE TPR_1 PF00515.23 GAM23625.1 - 0.00097 18.6 0.4 0.32 10.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM23625.1 - 0.0021 17.6 0.1 2.5 8.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM23625.1 - 0.0098 16.0 4.7 0.056 13.5 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAM23625.1 - 0.024 14.5 0.3 1.3 9.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM23625.1 - 0.039 13.5 0.1 1.1 8.9 0.0 3.3 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.1 GAM23625.1 - 0.13 12.9 0.1 56 4.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat 2C_adapt PF08793.5 GAM23625.1 - 0.15 11.9 0.2 0.72 9.7 0.1 2.2 2 0 0 2 2 2 0 2-cysteine adaptor domain TPR_8 PF13181.1 GAM23625.1 - 0.49 10.3 3.2 1 9.2 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RasGEF PF00617.14 GAM23627.1 - 5.8e-56 189.2 0.7 1.3e-55 188.0 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM23627.1 - 1e-19 70.5 0.4 1e-19 70.5 0.3 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif AA_kinase PF00696.23 GAM23628.1 - 3.7e-36 124.8 0.1 4.4e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Amino acid kinase family Rep-A_N PF04057.7 GAM23628.1 - 0.056 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DUF1712 PF08217.6 GAM23629.1 - 8.7e-63 212.5 12.9 1.2e-51 175.7 5.1 3.0 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) Shugoshin_N PF07558.6 GAM23629.1 - 0.31 10.7 1.6 0.49 10.1 0.1 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Peptidase_M8 PF01457.11 GAM23630.1 - 2.8e-68 230.5 7.5 6e-68 229.4 5.2 1.5 1 1 0 1 1 1 1 Leishmanolysin Frataxin_Cyay PF01491.11 GAM23631.1 - 2.1e-30 104.7 0.0 2.5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain SRP9-21 PF05486.7 GAM23635.1 - 3.5e-19 68.3 1.2 3.8e-19 68.2 0.9 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) MitMem_reg PF13012.1 GAM23636.1 - 1.6e-24 86.2 0.4 2.2e-24 85.7 0.2 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAM23636.1 - 1e-18 67.1 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RRM_1 PF00076.17 GAM23637.1 - 2.1e-24 84.9 0.0 2.3e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM23637.1 - 1.4e-19 69.8 0.0 2.6e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 GAM23637.1 - 4.5e-18 64.6 0.6 4.5e-18 64.6 0.4 2.2 2 0 0 2 2 2 1 Surp module RRM_5 PF13893.1 GAM23637.1 - 1.9e-12 46.8 0.8 7.4e-05 22.5 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 GAM23637.1 - 1.2e-08 35.0 0.0 2.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.3 GAM23637.1 - 3.7e-07 29.8 0.0 7.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 RRM_3 PF08777.6 GAM23637.1 - 6.7e-06 25.8 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif FAM70 PF14967.1 GAM23638.1 - 0.00021 20.6 1.1 0.00025 20.3 0.4 1.3 1 1 0 1 1 1 1 FAM70 protein Flavi_NS2A PF01005.14 GAM23638.1 - 0.0032 16.7 1.9 0.0044 16.3 1.3 1.2 1 0 0 1 1 1 1 Flavivirus non-structural protein NS2A Tetraspannin PF00335.15 GAM23638.1 - 0.0054 16.0 10.3 0.0099 15.1 7.2 1.6 1 1 0 1 1 1 1 Tetraspanin family ATP-synt_C PF00137.16 GAM23638.1 - 0.029 14.2 4.7 0.68 9.8 1.0 2.6 2 1 0 2 2 2 0 ATP synthase subunit C Transport_MerF PF11431.3 GAM23638.1 - 0.093 12.3 0.4 0.093 12.3 0.3 2.1 2 1 0 2 2 2 0 Membrane transport protein MerF DUF3290 PF11694.3 GAM23638.1 - 0.32 10.7 2.5 0.63 9.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2892 PF11127.3 GAM23638.1 - 0.46 10.3 7.9 0.26 11.1 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Oxidored_q2 PF00420.19 GAM23638.1 - 0.52 9.9 9.2 0.069 12.7 3.8 1.5 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Wzy_C PF04932.10 GAM23638.1 - 0.64 9.7 12.5 1.1 9.0 8.6 1.5 1 1 0 1 1 1 0 O-Antigen ligase MerC PF03203.9 GAM23638.1 - 1 9.7 6.6 2 8.7 4.5 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein DUF3975 PF13126.1 GAM23638.1 - 1.2 9.3 9.1 0.12 12.5 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) DUF3353 PF11833.3 GAM23638.1 - 2.1 7.7 6.5 2.4 7.5 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) PrgI PF12666.2 GAM23638.1 - 2.2 8.5 9.1 0.54 10.4 3.5 1.9 1 1 1 2 2 2 0 PrgI family protein AAA_16 PF13191.1 GAM23639.1 - 0.059 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dict-STAT-coil PF09267.5 GAM23640.1 - 4e-33 114.0 10.2 4e-33 114.0 7.1 2.3 2 1 0 2 2 2 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 GAM23640.1 - 2.8e-12 46.2 0.0 6.5e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.1 GAM23640.1 - 0.042 12.9 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 SH2 domain Cbl_N3 PF02762.9 GAM23640.1 - 0.11 12.1 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Polysacc_deac_3 PF15421.1 GAM23641.1 - 7.6 5.1 11.3 11 4.5 7.8 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase dUTPase PF00692.14 GAM23642.1 - 4.4e-12 45.5 0.0 6.1e-10 38.6 0.0 2.1 1 1 1 2 2 2 2 dUTPase Mgm101p PF06420.7 GAM23643.1 - 7.7e-76 253.1 0.0 1.1e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Glyco_tranf_2_3 PF13641.1 GAM23644.1 - 3.5e-26 92.4 0.0 2e-25 89.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM23644.1 - 4.1e-24 85.3 0.1 4.1e-24 85.3 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 GAM23644.1 - 4e-23 81.6 11.5 1.5e-14 53.2 1.0 3.8 3 1 1 4 4 4 3 Cellulose synthase Glyco_transf_21 PF13506.1 GAM23644.1 - 8.2e-08 31.7 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 GAM23644.1 - 1.2e-07 31.6 0.0 4.4e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.20 GAM23645.1 - 4.4e-63 212.8 0.0 1e-62 211.6 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23645.1 - 2.2e-46 158.0 0.0 3.9e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 GAM23645.1 - 7.1e-08 32.0 4.6 1.4e-07 31.0 3.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SBF2 PF12335.3 GAM23645.1 - 2.2e-07 30.4 1.0 2.2e-07 30.4 0.7 2.2 2 0 0 2 2 2 1 Myotubularin protein PBD PF00786.23 GAM23645.1 - 8.3e-07 29.3 0.2 8.3e-07 29.3 0.1 2.4 2 0 0 2 2 1 1 P21-Rho-binding domain CH PF00307.26 GAM23645.1 - 9.7e-06 25.5 0.3 9.7e-06 25.5 0.2 2.6 3 0 0 3 3 3 1 Calponin homology (CH) domain Kinase-like PF14531.1 GAM23645.1 - 1.5e-05 24.0 0.0 4.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DivIVA PF05103.8 GAM23645.1 - 0.39 10.7 10.3 2.8 8.0 0.9 2.7 2 0 0 2 2 2 0 DivIVA protein PHD PF00628.24 GAM23645.1 - 0.53 10.0 4.1 1.3 8.7 2.8 1.7 1 0 0 1 1 1 0 PHD-finger ATG16 PF08614.6 GAM23645.1 - 2.6 7.8 28.5 7.2 6.3 10.3 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 GAM23645.1 - 4.4 7.3 10.9 0.2 11.7 0.5 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein DivIC PF04977.10 GAM23645.1 - 5.6 6.5 9.0 7 6.2 1.1 2.8 2 0 0 2 2 2 0 Septum formation initiator Neisseria_TspB PF05616.8 GAM23646.1 - 4.6 5.4 6.8 6.5 5.0 4.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cna_B PF05738.8 GAM23647.1 - 2.1e-18 65.8 3.3 0.0016 18.1 0.0 6.8 5 0 0 5 5 5 4 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM23647.1 - 0.00022 21.2 0.2 0.083 12.9 0.0 7.9 6 1 0 6 6 6 4 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 GAM23647.1 - 0.00038 20.2 0.1 56 3.6 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2012) Y_Y_Y PF07495.8 GAM23647.1 - 0.0028 17.3 2.9 13 5.6 0.0 4.3 4 0 0 4 4 4 2 Y_Y_Y domain Pox_RNA_pol PF03293.9 GAM23647.1 - 0.015 14.8 0.1 29 4.1 0.0 3.9 3 0 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Macoilin PF09726.4 GAM23647.1 - 0.49 8.6 13.2 0.65 8.2 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Telomerase_RBD PF12009.3 GAM23648.1 - 2.5e-16 59.8 10.4 7.9e-14 51.7 5.8 3.5 2 1 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 GAM23648.1 - 1.5e-11 44.0 1.6 1.2e-10 41.1 1.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SURF4 PF02077.10 GAM23649.1 - 0.054 12.8 0.3 0.058 12.7 0.2 1.1 1 0 0 1 1 1 0 SURF4 family Shisa PF13908.1 GAM23649.1 - 0.13 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3951 PF13131.1 GAM23649.1 - 0.22 11.3 1.6 0.24 11.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) zf-TRAF PF02176.13 GAM23650.1 - 3.2e-11 43.4 6.8 3.2e-11 43.4 4.7 4.0 2 2 2 4 4 4 2 TRAF-type zinc finger MATH PF00917.21 GAM23650.1 - 4.9e-09 36.4 0.4 4.9e-09 36.4 0.3 2.8 3 0 0 3 3 3 1 MATH domain zf-RING_2 PF13639.1 GAM23650.1 - 8.1e-07 28.7 8.5 8.1e-07 28.7 5.9 3.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM23650.1 - 2.6e-06 27.3 11.4 2.6e-06 27.3 7.9 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM23650.1 - 0.00026 20.7 10.9 0.00026 20.7 7.5 3.3 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING ArsC PF03960.10 GAM23650.1 - 0.0081 16.2 0.2 0.029 14.4 0.2 2.0 1 0 0 1 1 1 1 ArsC family RasGEF PF00617.14 GAM23651.1 - 7.3e-59 198.6 2.4 1.7e-58 197.4 1.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM23651.1 - 5.5e-19 68.1 0.3 5.5e-19 68.1 0.2 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif FERM_N PF09379.5 GAM23651.1 - 3.6e-07 30.1 0.3 0.031 14.3 0.0 4.6 5 0 0 5 5 5 2 FERM N-terminal domain YukD PF08817.5 GAM23651.1 - 2.5e-05 24.7 0.0 0.26 11.8 0.0 3.5 3 0 0 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD RA PF00788.18 GAM23651.1 - 0.00027 21.3 0.0 0.43 11.1 0.0 4.0 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Rad60-SLD PF11976.3 GAM23651.1 - 0.0061 16.2 1.2 1.9 8.2 0.0 4.8 6 0 0 6 6 6 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM23651.1 - 0.012 14.9 0.0 15 5.0 0.0 4.3 5 0 0 5 5 5 0 Ubiquitin family PQ-loop PF04193.9 GAM23653.1 - 2.7e-09 36.4 1.2 2.7e-09 36.4 0.8 2.5 2 0 0 2 2 2 1 PQ loop repeat UbiA PF01040.13 GAM23653.1 - 0.062 12.5 7.5 0.05 12.8 4.4 1.4 1 1 0 1 1 1 0 UbiA prenyltransferase family HlyIII PF03006.15 GAM23653.1 - 3 7.1 13.3 5.1 6.4 9.2 1.3 1 0 0 1 1 1 0 Haemolysin-III related UDG PF03167.14 GAM23654.1 - 3.8e-23 81.6 0.0 7e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily tRNA-synt_2 PF00152.15 GAM23655.1 - 1.4e-48 165.3 0.6 2.2e-48 164.7 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 GAM23655.1 - 0.024 13.8 0.8 4.6 6.3 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Amidohydro_2 PF04909.9 GAM23656.1 - 6.9e-16 58.6 0.0 7.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase tRNA-synt_2 PF00152.15 GAM23657.1 - 3.2e-76 256.2 0.3 5.3e-76 255.5 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 GAM23657.1 - 9.8e-07 28.5 0.1 1.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 GAM23657.1 - 0.00012 21.3 1.5 0.43 9.7 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) CCDC-167 PF15188.1 GAM23657.1 - 1.7 8.6 8.6 0.036 14.0 0.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Complex1_LYR_1 PF13232.1 GAM23658.1 - 4.1e-14 52.5 0.5 5.1e-14 52.2 0.3 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM23658.1 - 7.7e-14 51.2 0.3 1.2e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Pkinase PF00069.20 GAM23659.1 - 3.1e-67 226.4 0.0 4.7e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23659.1 - 5.4e-47 160.0 0.0 8.3e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM23659.1 - 0.00087 19.0 0.0 0.026 14.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM23659.1 - 0.0085 15.0 0.0 0.018 13.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM23659.1 - 0.031 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 GAM23659.1 - 0.097 11.7 0.4 0.21 10.6 0.2 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase Lung_7-TM_R PF06814.8 GAM23660.1 - 1.2e-08 34.2 12.8 1.2e-08 34.2 8.9 2.2 2 0 0 2 2 2 1 Lung seven transmembrane receptor NmrA PF05368.8 GAM23661.1 - 2.2e-22 79.4 0.2 8.3e-21 74.3 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM23661.1 - 6.1e-06 25.1 0.0 1.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM23661.1 - 3.2e-05 23.9 0.0 5.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding EB PF01683.13 GAM23662.1 - 0.0028 17.6 21.6 0.0097 15.9 1.7 6.2 2 2 4 6 6 6 4 EB module Glycophorin_A PF01102.13 GAM23662.1 - 0.0036 17.0 1.3 0.0094 15.7 0.9 1.6 1 0 0 1 1 1 1 Glycophorin A Colipase PF01114.13 GAM23662.1 - 0.024 14.1 0.4 0.024 14.1 0.3 4.6 2 1 3 5 5 5 0 Colipase, N-terminal domain TMEM154 PF15102.1 GAM23662.1 - 0.25 11.0 2.1 0.67 9.6 1.5 1.7 1 0 0 1 1 1 0 TMEM154 protein family FNIP PF05725.7 GAM23663.1 - 5.2e-118 384.8 29.8 3.6e-14 52.4 0.3 10.1 2 2 12 15 15 15 15 FNIP Repeat DDE_Tnp_4 PF13359.1 GAM23665.1 - 3.6e-15 55.9 0.3 8.2e-14 51.5 0.2 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM23665.1 - 1.1e-05 25.1 1.6 1.5e-05 24.6 1.1 1.3 1 1 0 1 1 1 1 Transposase DDE domain RNase_PH_C PF03725.10 GAM23667.1 - 0.033 14.1 1.3 82 3.2 0.0 4.2 4 0 0 4 4 4 0 3' exoribonuclease family, domain 2 Ank_2 PF12796.2 GAM23669.1 - 2e-06 28.0 0.1 0.94 9.8 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM23669.1 - 0.0069 16.8 1.4 1.7e+02 2.9 0.0 5.8 7 0 0 7 7 7 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23669.1 - 0.016 15.4 0.8 1.5e+02 3.0 0.0 5.9 7 0 0 7 7 7 0 Ankyrin repeat DUF70 PF01901.11 GAM23669.1 - 0.069 12.1 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF70 eIF3_subunit PF08597.5 GAM23670.1 - 0.037 13.6 9.7 0.047 13.2 6.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Saw1 PF11561.3 GAM23670.1 - 0.068 12.5 6.5 0.025 13.9 2.6 1.6 1 1 1 2 2 2 0 Single strand annealing-weakened 1 SPT6_acidic PF14632.1 GAM23670.1 - 0.21 11.7 7.5 3.4 7.8 0.7 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 CD99L2 PF12301.3 GAM23670.1 - 0.25 11.0 11.2 1.6 8.4 3.9 2.1 1 1 1 2 2 2 0 CD99 antigen like protein 2 TP53IP5 PF15331.1 GAM23670.1 - 0.37 10.6 6.3 0.38 10.6 4.4 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Paramyxo_C PF01692.13 GAM23670.1 - 0.38 10.3 4.7 0.4 10.2 3.3 1.2 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Mucin PF01456.12 GAM23670.1 - 5.2 6.8 8.4 6.6 6.5 5.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3332 PF11810.3 GAM23670.1 - 6 6.4 7.6 7.6 6.1 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Oxidored_FMN PF00724.15 GAM23671.1 - 5.2e-80 268.9 0.0 6.7e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 GAM23671.1 - 0.005 15.7 0.0 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Lipase_3 PF01764.20 GAM23672.1 - 3.3e-32 111.0 0.0 4.3e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM23672.1 - 4.4e-05 22.9 0.0 0.00042 19.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 GAM23672.1 - 0.0014 18.2 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAM23672.1 - 0.063 12.5 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 GAM23673.1 - 1e-29 102.9 0.0 1.4e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM23673.1 - 3.4e-06 26.5 0.0 7.6e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.17 GAM23673.1 - 0.0016 18.2 0.3 0.01 15.5 0.2 2.0 1 1 0 1 1 1 1 Cutinase DUF676 PF05057.9 GAM23673.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Prp19_bind PF06991.6 GAM23674.1 - 0.35 10.1 3.0 1 8.5 0.2 2.0 1 1 1 2 2 2 0 Splicing factor, Prp19-binding domain TIG PF01833.19 GAM23675.1 - 1.6e-10 40.8 27.0 4.3e-08 33.0 3.1 3.8 4 0 0 4 4 4 3 IPT/TIG domain RasGEF PF00617.14 GAM23676.1 - 3.7e-34 118.0 0.2 7.7e-34 117.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM23676.1 - 9.3e-20 70.6 1.0 2.1e-19 69.5 0.2 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Viral_DNA_bi PF02236.12 GAM23676.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain LEDGF PF11467.3 GAM23676.1 - 0.19 11.4 1.5 1.3 8.7 0.3 2.4 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) Lyase_1 PF00206.15 GAM23677.1 - 1.7e-50 172.0 0.0 2.3e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 GAM23677.1 - 6e-46 155.0 0.1 1.5e-45 153.6 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal RasGEF PF00617.14 GAM23678.1 - 3.7e-46 157.2 0.2 7.1e-46 156.3 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain GRAM PF02893.15 GAM23678.1 - 4.8e-14 51.6 0.1 1.3e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 GRAM domain RhoGAP PF00620.22 GAM23678.1 - 1.9e-07 30.8 0.4 6.1e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.15 GAM23678.1 - 3.4e-05 23.8 0.0 3.4e-05 23.8 0.0 2.9 4 0 0 4 4 4 1 RasGEF N-terminal motif Ank_2 PF12796.2 GAM23679.1 - 1.5e-07 31.6 0.1 0.00048 20.4 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM23679.1 - 4e-05 23.2 0.1 0.77 9.6 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 GAM23679.1 - 0.00045 20.6 0.1 0.065 13.7 0.0 4.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM23679.1 - 0.00082 19.5 0.0 0.039 14.2 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23679.1 - 0.0014 18.6 0.2 76 4.0 0.0 6.0 7 0 0 7 7 7 0 Ankyrin repeat WD40 PF00400.27 GAM23680.1 - 1.1e-28 98.0 5.6 1.4e-07 31.0 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 GAM23680.1 - 0.014 13.5 1.4 2.7 6.0 0.1 3.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAM23680.1 - 0.05 13.3 0.3 18 5.1 0.0 3.6 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Myb_DNA-binding PF00249.26 GAM23682.1 - 8.3e-06 25.7 0.2 0.00032 20.6 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain SOBP PF15279.1 GAM23682.1 - 2.6e-05 24.7 40.3 2.6e-05 24.7 28.0 3.5 1 1 1 3 3 3 1 Sine oculis-binding protein 7tm_2 PF00002.19 GAM23683.1 - 0.00042 19.4 9.9 0.00042 19.4 6.9 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Herpes_UL45 PF05473.7 GAM23683.1 - 0.31 10.4 2.5 0.24 10.7 0.2 1.9 2 1 1 3 3 3 0 UL45 protein 7tm_1 PF00001.16 GAM23683.1 - 0.61 9.1 20.0 1 8.4 11.9 2.3 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 GAM23683.1 - 7.2 6.4 12.4 0.1 12.3 2.4 2.5 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term FNIP PF05725.7 GAM23684.1 - 2.4e-56 187.4 17.6 2.3e-12 46.6 0.1 8.5 5 2 3 8 8 8 7 FNIP Repeat Ribosomal_60s PF00428.14 GAM23685.1 - 2.2e-24 85.6 18.1 2.7e-24 85.3 12.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein P_C PF06640.6 GAM23685.1 - 0.036 14.0 4.4 0.044 13.7 3.0 1.0 1 0 0 1 1 1 0 P protein C-terminus DUF3138 PF11336.3 GAM23685.1 - 2.3 6.2 8.1 2.2 6.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DSPc PF00782.15 GAM23686.1 - 5.9e-30 103.5 0.0 8.2e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM23686.1 - 7.8e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAM23686.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 GAM23686.1 - 0.08 11.8 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase G-alpha PF00503.15 GAM23687.1 - 3.9e-111 371.4 2.9 5.1e-111 371.1 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM23687.1 - 2.2e-16 59.5 2.4 1.8e-12 46.8 0.5 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM23687.1 - 0.00029 20.0 3.2 0.028 13.5 0.1 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.17 GAM23687.1 - 0.00064 19.1 0.5 0.083 12.2 0.1 2.8 2 1 0 2 2 2 1 Ras family Miro PF08477.8 GAM23687.1 - 0.00072 20.0 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM23687.1 - 0.069 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 GAM23687.1 - 0.073 13.0 0.1 2.4 8.1 0.0 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM23687.1 - 0.1 12.0 0.4 7 6.0 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.21 GAM23687.1 - 0.12 11.8 0.3 0.55 9.6 0.2 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Fork_head PF00250.13 GAM23689.1 - 0.00089 19.2 0.0 0.0066 16.4 0.0 2.3 2 0 0 2 2 2 1 Fork head domain PAP1 PF08601.5 GAM23690.1 - 0.12 12.0 2.2 0.18 11.4 1.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Glyco_hydro_25 PF01183.15 GAM23692.1 - 3.4e-12 46.5 0.0 3.8e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Glyco_hydro_25 PF01183.15 GAM23693.1 - 2.1e-12 47.2 0.1 2.4e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 PAT1 PF09770.4 GAM23694.1 - 0.5 8.5 58.5 0.019 13.2 35.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 GAM23694.1 - 0.53 10.6 26.9 0.74 10.1 12.3 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein Med15 PF09606.5 GAM23694.1 - 2.9 5.9 74.4 0.025 12.8 44.4 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc80_HEC PF03801.8 GAM23697.1 - 3.6e-41 140.2 1.0 3.6e-41 140.2 0.7 3.1 2 1 0 2 2 2 1 HEC/Ndc80p family Ank_4 PF13637.1 GAM23698.1 - 6.4e-36 122.1 2.7 0.00024 21.5 0.0 9.8 7 1 2 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM23698.1 - 2.4e-33 114.3 10.3 2.2e-07 31.1 0.7 6.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM23698.1 - 4.3e-26 90.3 7.0 0.016 15.4 0.0 11.1 2 2 9 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23698.1 - 1.8e-21 74.0 6.8 1.1 9.6 0.0 12.7 8 2 5 13 13 13 3 Ankyrin repeat Ank PF00023.25 GAM23698.1 - 6.3e-20 69.9 9.0 1.6 8.6 0.0 12.3 12 1 1 13 13 13 5 Ankyrin repeat DUF3447 PF11929.3 GAM23698.1 - 8.1e-07 28.7 2.3 0.46 10.3 0.0 5.2 3 2 1 5 5 5 2 Domain of unknown function (DUF3447) RNase_P_p30 PF01876.11 GAM23698.1 - 0.0094 15.1 0.2 1.4 8.1 0.0 3.8 4 2 0 5 5 5 1 RNase P subunit p30 SH3BGR PF04908.10 GAM23699.1 - 2.5e-08 33.7 0.1 2.7e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 GAM23699.1 - 2.7e-08 33.6 0.0 3.8e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin CTP_synth_N PF06418.9 GAM23699.1 - 0.03 13.4 0.3 0.03 13.4 0.2 1.0 1 0 0 1 1 1 0 CTP synthase N-terminus RhoGAP PF00620.22 GAM23700.1 - 9.5e-35 119.4 0.1 2.3e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain BAR_2 PF10455.4 GAM23700.1 - 0.0036 16.2 5.2 0.14 11.0 2.8 2.4 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking Arfaptin PF06456.8 GAM23700.1 - 0.011 15.1 0.8 0.011 15.1 0.6 1.6 2 0 0 2 2 2 0 Arfaptin-like domain GAS PF13851.1 GAM23700.1 - 0.011 14.9 2.3 0.011 14.9 1.6 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Zip PF02535.17 GAM23700.1 - 0.047 12.6 5.0 0.068 12.1 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2363 PF10155.4 GAM23701.1 - 1.1e-47 161.1 6.3 2.6e-47 159.8 4.4 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) SNAPc_SNAP43 PF09808.4 GAM23701.1 - 0.024 14.3 0.4 0.024 14.3 0.3 3.0 3 0 0 3 3 3 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ammonium_transp PF00909.16 GAM23702.1 - 1.4e-62 211.4 13.8 4.3e-58 196.7 8.1 2.9 1 1 1 2 2 2 2 Ammonium Transporter Family FNIP PF05725.7 GAM23703.1 - 8.7e-74 243.2 33.5 1.1e-14 54.1 1.7 9.6 4 3 3 9 9 9 9 FNIP Repeat SIR2_2 PF13289.1 GAM23704.1 - 0.029 14.2 0.1 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 SIR2-like domain LRR_4 PF12799.2 GAM23704.1 - 0.11 12.1 0.7 13 5.5 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 GAM23705.1 - 1.4e-103 338.6 58.5 7e-14 51.4 3.5 11.3 8 3 2 11 11 11 10 FNIP Repeat DUF4201 PF13870.1 GAM23705.1 - 0.016 14.6 0.8 0.03 13.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF904 PF06005.7 GAM23705.1 - 0.056 13.7 5.5 0.14 12.4 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 GAM23705.1 - 0.61 9.6 3.0 1.9 8.0 2.0 1.8 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 GAM23705.1 - 0.74 9.8 4.3 2.4 8.2 0.2 2.4 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 GAM23705.1 - 4 7.3 7.9 9.7 6.1 1.0 2.5 1 1 1 2 2 2 0 Basic region leucine zipper RmlD_sub_bind PF04321.12 GAM23706.1 - 3e-54 183.8 0.0 3.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAM23706.1 - 2e-20 73.2 0.0 2.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM23706.1 - 2e-12 46.6 0.0 9e-12 44.4 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 GAM23706.1 - 2.4e-07 29.9 0.1 1.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 GAM23706.1 - 1.8e-06 26.8 0.0 2.9e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM23706.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 GAM23706.1 - 0.0027 17.6 0.1 0.024 14.5 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase FNIP PF05725.7 GAM23707.1 - 7.1e-104 339.5 35.5 7.6e-14 51.3 0.1 12.4 5 2 7 14 14 14 14 FNIP Repeat DUF1769 PF08588.5 GAM23707.1 - 1.5e-05 24.8 0.8 2.5 8.1 0.0 5.9 4 1 1 5 5 5 1 Protein of unknown function (DUF1769) bZIP_2 PF07716.10 GAM23707.1 - 0.036 13.8 7.8 1.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Basic region leucine zipper CENP-H PF05837.7 GAM23707.1 - 0.068 13.3 2.9 0.15 12.2 2.0 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Ead_Ea22 PF13935.1 GAM23707.1 - 0.096 13.0 1.8 0.16 12.2 1.2 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF2205 PF10224.4 GAM23707.1 - 0.13 11.8 1.8 0.74 9.4 1.4 2.0 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) HALZ PF02183.13 GAM23707.1 - 0.67 9.7 11.0 2.1 8.1 2.1 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 GAM23707.1 - 0.73 9.3 8.7 0.7 9.4 1.6 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 GAM23707.1 - 2.1 8.6 8.7 5.5 7.3 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 GAM23707.1 - 4.8 7.2 7.5 9.4 6.2 0.5 2.2 1 1 1 2 2 2 0 bZIP transcription factor Acyl_transf_3 PF01757.17 GAM23708.1 - 2.3e-11 43.1 34.1 2.7e-11 42.9 23.7 1.1 1 0 0 1 1 1 1 Acyltransferase family FNIP PF05725.7 GAM23709.1 - 9.1e-74 243.1 30.4 5.5e-12 45.4 0.1 10.8 6 2 6 12 12 12 12 FNIP Repeat Macoilin PF09726.4 GAM23709.1 - 0.03 12.6 4.9 0.04 12.2 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein UPF0242 PF06785.6 GAM23709.1 - 0.09 11.4 9.4 0.14 10.7 6.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) AAA_23 PF13476.1 GAM23709.1 - 0.15 12.3 7.0 0.22 11.8 4.9 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 GAM23709.1 - 0.37 9.7 7.4 0.76 8.7 5.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 GAM23709.1 - 0.84 9.4 7.7 8.4 6.2 2.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper BLOC1_2 PF10046.4 GAM23709.1 - 0.86 9.7 7.5 2.1 8.5 5.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 GAM23709.1 - 1.3 8.5 7.4 2.6 7.5 5.1 1.4 1 0 0 1 1 1 0 IncA protein DUF1875 PF08961.5 GAM23709.1 - 1.5 8.0 9.1 3.4 6.9 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF904 PF06005.7 GAM23709.1 - 3.3 8.0 14.2 19 5.6 9.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 GAM23709.1 - 5.5 7.3 9.3 1.9e+02 2.4 6.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) FNIP PF05725.7 GAM23710.1 - 1e-71 236.5 35.2 2.9e-10 39.9 0.1 10.9 4 2 8 13 13 13 13 FNIP Repeat Macoilin PF09726.4 GAM23710.1 - 0.0066 14.8 6.0 0.0089 14.3 4.2 1.1 1 0 0 1 1 1 1 Transmembrane protein Rootletin PF15035.1 GAM23710.1 - 0.035 14.0 8.5 0.051 13.5 5.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_2 PF07716.10 GAM23710.1 - 0.13 12.0 7.8 1.9 8.3 1.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper DUF1875 PF08961.5 GAM23710.1 - 0.18 11.0 12.4 0.29 10.4 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF3186 PF11382.3 GAM23710.1 - 0.73 8.9 4.9 1.3 8.0 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DivIC PF04977.10 GAM23710.1 - 0.86 9.1 8.7 2.7 7.5 0.3 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 GAM23710.1 - 1.2 9.5 8.5 2.9 8.2 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 GAM23710.1 - 1.2 8.9 11.3 6.8 6.4 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper UPF0242 PF06785.6 GAM23710.1 - 1.5 7.4 9.6 2.4 6.7 6.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF904 PF06005.7 GAM23710.1 - 1.9 8.8 15.9 11 6.3 11.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) FNIP PF05725.7 GAM23711.1 - 1.3e-68 226.6 37.5 5e-11 42.3 0.1 12.7 10 4 2 13 13 13 10 FNIP Repeat Tho2 PF11262.3 GAM23711.1 - 0.037 13.0 2.2 0.072 12.1 1.5 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 APG6 PF04111.7 GAM23711.1 - 0.049 12.6 7.7 0.11 11.5 5.4 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1875 PF08961.5 GAM23711.1 - 0.1 11.9 9.3 0.22 10.8 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF904 PF06005.7 GAM23711.1 - 0.21 11.9 15.4 1.2 9.4 10.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Spc7 PF08317.6 GAM23711.1 - 0.24 10.0 7.4 0.37 9.4 5.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_2 PF07716.10 GAM23711.1 - 0.43 10.4 11.4 0.36 10.6 0.5 2.8 3 0 0 3 3 3 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.4 GAM23711.1 - 0.63 10.0 7.3 12 5.9 6.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.15 GAM23711.1 - 0.64 9.8 9.0 4.4 7.1 2.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 GAM23711.1 - 0.66 9.4 11.6 0.8 9.2 0.5 2.6 2 1 0 2 2 2 0 Septum formation initiator UPF0242 PF06785.6 GAM23711.1 - 0.69 8.5 6.6 1 7.9 4.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Atg14 PF10186.4 GAM23711.1 - 0.78 8.6 7.0 1.3 7.8 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 GAM23711.1 - 1.2 9.1 9.1 5.5 7.0 0.5 2.6 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.13 GAM23711.1 - 1.3 8.7 11.4 8.9 6.1 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Seadorna_VP6 PF07407.6 GAM23711.1 - 2.6 6.7 4.5 2.5 6.7 1.1 1.8 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF4140 PF13600.1 GAM23711.1 - 5.5 7.5 4.9 47 4.4 1.1 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3186 PF11382.3 GAM23711.1 - 7.4 5.6 8.9 4.6 6.2 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) FNIP PF05725.7 GAM23712.1 - 1.1e-74 246.0 34.6 1.2e-09 37.9 0.0 11.4 9 1 3 12 12 11 11 FNIP Repeat BLOC1_2 PF10046.4 GAM23712.1 - 0.00061 19.8 2.3 0.0013 18.8 1.6 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AKNA PF12443.3 GAM23712.1 - 0.00073 19.5 2.1 0.0019 18.1 1.5 1.6 1 0 0 1 1 1 1 AT-hook-containing transcription factor YlqD PF11068.3 GAM23712.1 - 0.0028 17.6 2.0 0.0054 16.7 1.4 1.4 1 0 0 1 1 1 1 YlqD protein AAA_23 PF13476.1 GAM23712.1 - 0.013 15.8 3.1 0.018 15.3 2.1 1.2 1 0 0 1 1 1 0 AAA domain bZIP_2 PF07716.10 GAM23712.1 - 0.017 14.9 1.8 0.017 14.9 1.2 2.1 2 0 0 2 2 1 0 Basic region leucine zipper Spc7 PF08317.6 GAM23712.1 - 0.021 13.4 2.8 0.033 12.8 1.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CortBP2 PF09727.4 GAM23712.1 - 0.022 14.2 3.2 0.033 13.6 2.2 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 TMF_TATA_bd PF12325.3 GAM23712.1 - 0.025 14.3 3.2 0.046 13.4 2.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 GAM23712.1 - 0.027 14.7 1.0 0.057 13.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) LRR_5 PF13306.1 GAM23712.1 - 0.027 14.1 0.1 0.4 10.4 0.1 2.7 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) Sipho_Gp157 PF05565.6 GAM23712.1 - 0.028 14.0 1.9 0.03 13.9 0.4 1.6 2 0 0 2 2 2 0 Siphovirus Gp157 DUF3450 PF11932.3 GAM23712.1 - 0.062 12.5 2.0 0.11 11.7 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin PF00804.20 GAM23712.1 - 0.094 12.8 4.5 0.08 13.1 1.0 2.1 2 0 0 2 2 2 0 Syntaxin Med21 PF11221.3 GAM23712.1 - 0.18 11.7 5.1 1.4 8.8 2.2 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF948 PF06103.6 GAM23712.1 - 0.19 11.5 0.5 0.45 10.4 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 GAM23712.1 - 0.25 10.9 3.5 0.4 10.2 2.4 1.2 1 0 0 1 1 1 0 IncA protein Ran-binding PF05508.6 GAM23712.1 - 0.27 10.0 6.1 0.75 8.6 4.2 1.7 1 1 0 1 1 1 0 RanGTP-binding protein NPV_P10 PF05531.7 GAM23712.1 - 0.43 10.8 4.0 1.2 9.3 2.8 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 GAM23712.1 - 1.1 9.0 7.7 2.5 7.9 5.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FNIP PF05725.7 GAM23713.1 - 3e-73 241.5 17.4 1.8e-10 40.5 0.0 10.9 8 2 3 11 11 11 11 FNIP Repeat Rab5-bind PF09311.6 GAM23713.1 - 0.0012 18.7 6.0 0.0022 17.8 4.2 1.3 1 0 0 1 1 1 1 Rabaptin-like protein Tho2 PF11262.3 GAM23713.1 - 0.0018 17.3 5.8 0.0039 16.2 4.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 bZIP_1 PF00170.16 GAM23713.1 - 0.0059 16.5 10.9 0.11 12.5 3.5 2.5 1 1 1 2 2 2 2 bZIP transcription factor FlxA PF14282.1 GAM23713.1 - 0.076 12.9 12.8 0.038 13.9 7.2 1.7 2 0 0 2 2 1 0 FlxA-like protein APG6 PF04111.7 GAM23713.1 - 0.094 11.7 12.8 0.17 10.8 8.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_MT_bd PF06657.8 GAM23713.1 - 0.11 12.4 5.6 0.23 11.4 3.9 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 ADIP PF11559.3 GAM23713.1 - 0.11 12.3 13.1 0.23 11.3 9.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 GAM23713.1 - 0.12 11.9 15.1 0.62 9.5 1.0 2.4 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.13 GAM23713.1 - 0.17 11.5 9.7 3.6 7.3 2.2 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 GAM23713.1 - 0.23 11.3 12.9 1.8 8.4 1.1 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DUF342 PF03961.8 GAM23713.1 - 0.23 9.8 9.0 0.34 9.2 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 GAM23713.1 - 0.27 11.5 10.0 0.52 10.6 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) LRR_7 PF13504.1 GAM23713.1 - 0.36 11.2 13.5 73 4.2 0.0 8.4 9 1 0 9 9 8 0 Leucine rich repeat Rootletin PF15035.1 GAM23713.1 - 0.37 10.7 16.7 1.4 8.9 11.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AKNA PF12443.3 GAM23713.1 - 0.52 10.3 8.1 1.1 9.2 3.5 2.3 1 1 1 2 2 2 0 AT-hook-containing transcription factor LRR_1 PF00560.28 GAM23713.1 - 0.55 10.4 14.1 11 6.4 0.0 6.6 5 2 0 5 5 5 0 Leucine Rich Repeat Bap31 PF05529.7 GAM23713.1 - 1.1 8.7 7.9 1.8 7.9 5.5 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 GAM23713.1 - 2.8 8.4 8.5 27 5.2 0.3 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.4 GAM23713.1 - 3.8 7.3 14.0 35 4.1 9.7 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain FlaC_arch PF05377.6 GAM23713.1 - 4.7 7.1 8.4 52 3.8 5.8 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 GAM23713.1 - 5.8 7.2 20.6 1.4e+02 2.8 14.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) SlyX PF04102.7 GAM23713.1 - 6.2 7.2 7.9 11 6.5 0.7 2.8 1 1 1 2 2 2 0 SlyX Fzo_mitofusin PF04799.8 GAM23713.1 - 8.5 5.7 10.1 13 5.1 5.7 2.0 1 1 1 2 2 2 0 fzo-like conserved region AAA PF00004.24 GAM23714.1 - 1.8e-91 303.2 0.0 1.9e-44 151.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM23714.1 - 1.6e-15 56.7 0.0 1.8e-07 30.4 0.0 3.1 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 GAM23714.1 - 2.8e-10 40.0 0.2 3.9e-05 23.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM23714.1 - 3.3e-10 40.2 0.1 3.4e-05 23.9 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAM23714.1 - 3.9e-09 36.7 0.3 0.012 15.7 0.0 4.2 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.8 GAM23714.1 - 3.2e-08 32.6 0.0 0.00029 19.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 GAM23714.1 - 5e-08 32.9 0.0 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 GAM23714.1 - 2.8e-07 30.5 0.0 0.01 15.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 GAM23714.1 - 3.6e-07 31.0 0.3 0.0063 17.3 0.0 2.7 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM23714.1 - 1.4e-06 28.4 0.0 0.022 14.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 GAM23714.1 - 4.7e-06 25.9 0.2 0.049 12.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAM23714.1 - 9.7e-06 25.1 2.6 0.93 8.8 0.1 3.9 2 2 0 3 3 3 2 AAA domain AAA_33 PF13671.1 GAM23714.1 - 9.9e-06 25.4 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 GAM23714.1 - 2.2e-05 23.9 0.1 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 GAM23714.1 - 6.6e-05 22.9 0.0 0.52 10.3 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 GAM23714.1 - 9e-05 21.6 0.1 0.22 10.5 0.0 2.8 3 0 0 3 3 3 2 KaiC AAA_19 PF13245.1 GAM23714.1 - 9.5e-05 22.0 0.5 0.0073 16.0 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 GAM23714.1 - 0.00012 21.2 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.10 GAM23714.1 - 0.00016 20.4 0.0 0.039 12.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 GAM23714.1 - 0.00017 21.3 0.0 0.052 13.2 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 GAM23714.1 - 0.00021 21.6 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 GAM23714.1 - 0.00021 21.5 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAM23714.1 - 0.0003 20.4 0.7 0.061 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 GAM23714.1 - 0.00033 20.2 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM23714.1 - 0.00077 18.9 0.0 0.25 10.7 0.0 3.4 3 1 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.1 GAM23714.1 - 0.0017 18.3 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 GAM23714.1 - 0.0025 17.6 0.0 0.049 13.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 GAM23714.1 - 0.0057 15.6 0.0 1.9 7.3 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 GAM23714.1 - 0.0058 16.3 2.2 1.1 8.8 0.0 4.4 4 1 1 5 5 5 1 NACHT domain Serglycin PF04360.7 GAM23714.1 - 0.0073 16.0 0.5 3 7.5 0.2 2.3 2 0 0 2 2 2 1 Serglycin PhoH PF02562.11 GAM23714.1 - 0.027 13.7 0.1 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 GAM23714.1 - 0.035 12.9 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 GAM23714.1 - 0.038 13.5 0.0 0.75 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM23714.1 - 0.054 13.1 0.1 6.5 6.4 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 GAM23714.1 - 0.076 11.9 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) RRM_1 PF00076.17 GAM23715.1 - 5.2e-08 32.3 0.0 8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 GAM23715.1 - 2.7e-07 30.2 2.3 4.6e-07 29.4 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_6 PF14259.1 GAM23715.1 - 3.4e-07 30.1 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.1 GAM23715.1 - 0.00043 19.7 1.2 0.00078 18.8 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.1 GAM23715.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 GAM23715.1 - 0.02 14.5 0.7 0.02 14.5 0.5 1.8 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_S10 PF00338.17 GAM23716.1 - 3.6e-26 90.8 0.2 4.2e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DCP2 PF05026.8 GAM23717.1 - 4e-33 113.1 2.1 4e-33 113.1 1.5 3.2 4 0 0 4 4 4 1 Dcp2, box A domain NUDIX PF00293.23 GAM23717.1 - 1.4e-15 57.1 0.0 2.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF106 PF01956.11 GAM23717.1 - 1.3 8.5 8.2 6.3 6.3 0.9 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF1395 PF07160.7 GAM23717.1 - 7.1 6.0 19.6 0.6 9.5 4.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) Pkinase_Tyr PF07714.12 GAM23718.1 - 3.3e-59 200.0 0.0 5.1e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23718.1 - 5.9e-51 173.1 0.0 9.8e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM23718.1 - 0.00022 20.9 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.9 GAM23718.1 - 0.0019 18.2 0.1 0.0061 16.5 0.0 1.8 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain APH PF01636.18 GAM23718.1 - 0.0061 16.3 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Vps16_C PF04840.7 GAM23718.1 - 0.098 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region MRG PF05712.8 GAM23719.1 - 1.5e-46 157.7 1.0 1.5e-46 157.7 0.7 1.8 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 GAM23719.1 - 2.4e-08 33.5 3.8 6.3e-08 32.2 2.7 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 GAM23719.1 - 0.0081 15.8 1.0 0.029 14.0 0.7 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Miff PF05644.6 GAM23719.1 - 0.011 15.4 2.4 0.03 13.9 1.7 1.7 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff PWWP PF00855.12 GAM23719.1 - 0.011 15.9 1.6 0.034 14.3 1.1 1.9 1 0 0 1 1 1 0 PWWP domain CBM_5_12 PF02839.9 GAM23719.1 - 0.028 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain DDHD PF02862.12 GAM23719.1 - 0.054 13.2 6.6 0.08 12.7 4.6 1.3 1 0 0 1 1 1 0 DDHD domain Mgr1 PF08602.5 GAM23719.1 - 0.058 12.3 5.4 0.037 13.0 1.8 1.9 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Dicty_REP PF05086.7 GAM23719.1 - 0.095 10.4 6.7 0.12 10.0 4.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAM23719.1 - 0.095 12.4 3.1 0.17 11.6 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PIH1 PF08190.7 GAM23719.1 - 0.53 9.6 11.4 0.88 8.9 7.9 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 SSP160 PF06933.6 GAM23719.1 - 0.66 7.8 3.8 0.81 7.5 2.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 GAM23719.1 - 2.6 7.7 12.2 4.2 7.1 8.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PH_4 PF15404.1 GAM23719.1 - 3.9 6.9 11.0 2.3 7.7 6.1 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain Apc15p PF05841.6 GAM23719.1 - 9.1 7.0 16.1 4.1 8.1 9.4 1.7 2 0 0 2 2 1 0 Apc15p protein Ist1 PF03398.9 GAM23720.1 - 8e-52 174.9 3.1 1e-51 174.6 2.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cyt-b5 PF00173.23 GAM23721.1 - 5.1e-14 51.8 0.1 1.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 GAM23721.1 - 1e-13 51.3 33.8 1.6e-13 50.7 10.5 3.3 3 0 0 3 3 3 3 Fatty acid desaturase Abhydrolase_6 PF12697.2 GAM23722.1 - 9.7e-12 45.2 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM23722.1 - 8.3e-08 32.0 0.1 5.8e-07 29.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM23722.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Spt20 PF12090.3 GAM23722.1 - 0.4 10.0 11.6 1.1 8.5 8.1 1.6 1 1 0 1 1 1 0 Spt20 family TPR_11 PF13414.1 GAM23723.1 - 1.8e-13 49.8 7.0 2.4e-12 46.3 2.6 1.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM23723.1 - 2.7e-11 42.5 5.1 4.6e-05 22.8 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM23723.1 - 2.5e-10 40.7 0.6 4.3e-10 39.9 0.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM23723.1 - 5.6e-10 38.2 5.6 0.00036 20.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM23723.1 - 5.9e-10 38.2 6.7 3.5e-05 23.3 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM23723.1 - 1.1e-07 31.6 1.7 2.9e-07 30.3 1.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM23723.1 - 6.9e-07 29.3 0.3 0.0019 18.6 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM23723.1 - 1e-06 28.0 1.2 0.043 13.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM23723.1 - 0.0014 18.4 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM23723.1 - 0.0022 18.2 2.0 0.006 16.9 1.3 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM23723.1 - 0.0068 16.2 2.4 0.16 11.9 0.7 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 GAM23723.1 - 0.012 15.4 4.2 0.023 14.5 0.6 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain HCNGP PF07818.8 GAM23723.1 - 0.025 14.6 0.0 0.025 14.6 0.0 2.5 2 1 0 2 2 2 0 HCNGP-like protein Apc3 PF12895.2 GAM23723.1 - 0.028 14.5 1.3 3 8.0 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM23723.1 - 0.11 13.0 1.0 19 5.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Atrophin-1 PF03154.10 GAM23723.1 - 0.15 10.2 10.8 0.2 9.7 7.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family TPR_17 PF13431.1 GAM23723.1 - 0.71 10.2 6.2 5.7 7.3 0.9 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Mod_r PF07200.8 GAM23724.1 - 7.9e-05 22.6 11.1 0.00014 21.8 7.7 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein GAS PF13851.1 GAM23724.1 - 0.00053 19.2 15.5 0.0012 18.0 10.1 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Sec34 PF04136.10 GAM23724.1 - 0.0007 19.3 3.8 0.0011 18.6 2.6 1.3 1 0 0 1 1 1 1 Sec34-like family Fib_alpha PF08702.5 GAM23724.1 - 0.0065 16.6 6.6 0.014 15.5 4.6 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 GAM23724.1 - 0.019 15.0 5.0 0.028 14.4 3.5 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4263 PF14082.1 GAM23724.1 - 0.021 14.7 3.8 0.033 14.1 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) TMF_TATA_bd PF12325.3 GAM23724.1 - 0.028 14.1 7.2 0.051 13.3 5.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 GAM23724.1 - 0.031 14.0 12.0 0.057 13.1 8.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 GAM23724.1 - 0.037 11.8 5.4 0.046 11.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 GAM23724.1 - 0.054 12.5 1.8 0.079 11.9 1.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IncA PF04156.9 GAM23724.1 - 0.068 12.7 8.8 0.11 12.1 6.1 1.2 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 GAM23724.1 - 0.097 12.4 3.0 0.16 11.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 GAM23724.1 - 0.12 10.7 5.1 0.14 10.5 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ATG16 PF08614.6 GAM23724.1 - 0.14 11.9 9.7 0.23 11.2 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.6 GAM23724.1 - 0.17 11.3 12.8 0.35 10.3 8.9 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 SlyX PF04102.7 GAM23724.1 - 0.2 12.0 4.4 4.8 7.6 0.2 2.4 1 1 1 2 2 2 0 SlyX APG6 PF04111.7 GAM23724.1 - 0.21 10.6 11.7 0.29 10.1 8.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3450 PF11932.3 GAM23724.1 - 0.21 10.8 6.7 0.35 10.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 GAM23724.1 - 0.24 10.3 7.3 0.4 9.5 5.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 GAM23724.1 - 0.26 11.0 3.9 0.44 10.2 2.7 1.3 1 0 0 1 1 1 0 Laminin Domain II CENP-H PF05837.7 GAM23724.1 - 0.37 10.9 9.0 0.51 10.5 5.9 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) MRP-S23 PF10484.4 GAM23724.1 - 0.42 10.5 5.2 0.72 9.7 3.2 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 bZIP_1 PF00170.16 GAM23724.1 - 0.91 9.5 13.8 4.7 7.2 3.0 2.6 2 1 0 2 2 2 0 bZIP transcription factor Med9 PF07544.8 GAM23724.1 - 1.4 8.6 7.8 1.7 8.4 1.3 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 EAP30 PF04157.11 GAM23724.1 - 1.7 7.7 6.3 4.1 6.5 3.6 2.1 1 1 1 2 2 2 0 EAP30/Vps36 family Alba PF01918.16 GAM23724.1 - 3.4 7.3 5.8 0.46 10.0 0.5 2.2 3 0 0 3 3 2 0 Alba Rad9 PF04139.8 GAM23725.1 - 8.2e-53 179.0 4.4 1.1e-52 178.7 3.1 1.1 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.13 GAM23725.1 - 0.004 16.6 1.0 0.013 15.0 0.3 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain DPM2 PF07297.7 GAM23727.1 - 8e-17 61.2 0.1 8.6e-17 61.2 0.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Ribosomal_L15e PF00827.12 GAM23728.1 - 3.4e-92 307.2 6.2 4.4e-92 306.8 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L15 DUF2117 PF09890.4 GAM23728.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Phospholip_B PF04916.8 GAM23730.1 - 1.7e-118 396.1 9.1 2.3e-118 395.7 6.3 1.0 1 0 0 1 1 1 1 Phospholipase B E2F_TDP PF02319.15 GAM23731.1 - 2.6e-21 74.9 0.6 1.3e-12 47.0 0.1 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain BAP PF06639.6 GAM23731.1 - 0.35 10.5 1.9 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Basal layer antifungal peptide (BAP) NOA36 PF06524.7 GAM23731.1 - 3 7.0 11.3 5.9 6.0 7.8 1.5 1 0 0 1 1 1 0 NOA36 protein 4HBT PF03061.17 GAM23732.1 - 0.00096 19.2 0.0 0.0031 17.5 0.0 1.8 1 1 0 1 1 1 1 Thioesterase superfamily tRNA_int_endo PF01974.12 GAM23733.1 - 8e-20 70.4 0.0 1.5e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain HTH_3 PF01381.17 GAM23734.1 - 3e-15 55.7 0.1 4.8e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 GAM23734.1 - 2.2e-09 37.2 0.1 6e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.1 GAM23734.1 - 7e-07 29.3 0.0 2e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_37 PF13744.1 GAM23734.1 - 0.0017 18.1 0.1 0.0026 17.5 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MBF1 PF08523.5 GAM23734.1 - 0.0054 16.7 0.2 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 B_lectin PF01453.19 GAM23736.1 - 7.3e-39 132.1 3.8 4.8e-15 55.4 0.3 3.8 2 2 1 3 3 3 3 D-mannose binding lectin AbrB-like PF14250.1 GAM23736.1 - 0.00025 20.8 3.0 6.7 6.6 0.0 4.7 3 2 2 5 5 5 3 AbrB-like transcriptional regulator IN_DBD_C PF00552.16 GAM23736.1 - 0.0044 16.4 0.0 0.41 10.1 0.0 2.9 2 1 0 2 2 2 1 Integrase DNA binding domain zf-CHY PF05495.7 GAM23737.1 - 1.2e-16 60.6 14.5 1.3e-16 60.4 10.0 1.0 1 0 0 1 1 1 1 CHY zinc finger zf-ribbon_3 PF13248.1 GAM23737.1 - 0.0027 16.8 8.8 0.018 14.2 2.7 2.5 2 1 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM23737.1 - 0.021 14.2 9.0 0.12 11.8 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DUF1074 PF06382.6 GAM23737.1 - 0.049 13.6 1.8 0.055 13.4 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) Zn_Tnp_IS1595 PF12760.2 GAM23737.1 - 0.083 12.7 12.9 1.1 9.1 5.9 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 GAM23737.1 - 0.17 11.7 14.3 0.85 9.4 9.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 GAM23737.1 - 0.19 11.4 14.1 0.54 9.9 0.5 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-RING_3 PF14369.1 GAM23737.1 - 0.27 11.2 9.1 0.44 10.5 0.1 3.2 2 1 1 3 3 3 0 zinc-finger Tmemb_55A PF09788.4 GAM23737.1 - 0.34 10.0 7.5 0.37 9.8 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A A2L_zn_ribbon PF08792.5 GAM23737.1 - 0.47 9.9 6.8 5.1 6.6 0.1 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Elf1 PF05129.8 GAM23737.1 - 0.58 9.8 10.7 1.4 8.6 7.5 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 GAM23737.1 - 0.59 10.1 17.0 0.74 9.8 3.8 2.7 1 1 0 2 2 2 0 Zinc ribbon domain Cytochrome_C7 PF14522.1 GAM23737.1 - 0.73 9.5 10.7 1.1 8.9 7.4 1.3 1 0 0 1 1 1 0 Cytochrome c7 NOB1_Zn_bind PF08772.6 GAM23737.1 - 1.1 9.1 10.3 0.061 13.1 2.6 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF164 PF02591.10 GAM23737.1 - 1.9 8.3 9.1 0.33 10.8 0.3 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C2H2_6 PF13912.1 GAM23737.1 - 2.1 8.3 8.3 1.3 9.0 0.1 3.4 3 1 1 4 4 4 0 C2H2-type zinc finger zf-rbx1 PF12678.2 GAM23737.1 - 2.7 8.1 11.1 3.2 7.9 7.7 1.2 1 0 0 1 1 1 0 RING-H2 zinc finger HypA PF01155.14 GAM23737.1 - 3.2 7.4 11.6 0.74 9.5 2.2 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Ribosomal_L37ae PF01780.14 GAM23737.1 - 3.3 7.6 6.3 1.2 9.0 2.2 1.7 1 1 1 2 2 2 0 Ribosomal L37ae protein family DUF2296 PF10058.4 GAM23737.1 - 4.8 7.0 9.3 0.49 10.1 0.9 2.4 1 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) ABC_tran PF00005.22 GAM23738.1 - 8.5e-33 113.5 0.0 2.1e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 GAM23738.1 - 9.1e-25 87.5 16.6 1.2e-24 87.1 11.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 GAM23738.1 - 5.8e-07 28.9 0.7 5.1e-05 22.6 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM23738.1 - 4.8e-05 23.4 2.4 0.099 12.5 0.0 3.1 2 2 1 4 4 4 2 AAA domain AAA_17 PF13207.1 GAM23738.1 - 0.0023 18.7 0.0 0.0062 17.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 GAM23738.1 - 0.0024 17.0 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM23738.1 - 0.0052 17.1 0.4 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 GAM23738.1 - 0.0067 15.9 0.1 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM23738.1 - 0.0084 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM23738.1 - 0.013 15.6 0.6 0.15 12.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 GAM23738.1 - 0.024 14.4 0.0 0.065 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_5 PF07728.9 GAM23738.1 - 0.027 14.1 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAM23738.1 - 0.027 13.8 0.0 0.15 11.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain DEAD PF00270.24 GAM23738.1 - 0.045 13.2 0.1 0.22 11.0 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase Latexin PF06907.7 GAM23738.1 - 0.049 12.8 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Latexin MMR_HSR1 PF01926.18 GAM23738.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SURF6 PF04935.7 GAM23739.1 - 5.3e-27 94.5 42.0 5.3e-27 94.5 29.1 2.3 1 1 2 3 3 3 1 Surfeit locus protein 6 Atg14 PF10186.4 GAM23739.1 - 4.7 6.0 15.9 12 4.6 11.0 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HECT PF00632.20 GAM23740.1 - 4.1e-43 147.7 0.0 7.5e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.14 GAM23740.1 - 6.2e-21 74.8 6.2 1.7e-16 60.6 0.3 3.6 4 0 0 4 4 4 2 Filamin/ABP280 repeat zf-MYND PF01753.13 GAM23741.1 - 5.2e-10 39.0 8.5 8.5e-10 38.3 5.9 1.4 1 0 0 1 1 1 1 MYND finger Med3 PF11593.3 GAM23741.1 - 0.22 10.7 6.3 0.3 10.2 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal VirionAssem_T7 PF11653.3 GAM23741.1 - 0.34 11.7 2.9 0.81 10.4 2.0 1.7 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Fibrinogen_aC PF12160.3 GAM23741.1 - 0.38 10.2 3.6 0.68 9.4 2.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain Herpes_capsid PF06112.6 GAM23741.1 - 1 9.4 4.6 1.7 8.6 3.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DEC-1_N PF04625.8 GAM23741.1 - 1.2 7.6 7.4 1.9 7.1 5.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-HIT PF04438.11 GAM23741.1 - 7.5 6.3 9.4 20 4.9 6.5 1.8 1 0 0 1 1 1 0 HIT zinc finger GTP_EFTU PF00009.22 GAM23742.1 - 4.1e-59 199.1 0.0 6.3e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM23742.1 - 2.9e-34 117.2 0.0 5.5e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM23742.1 - 2.6e-20 72.0 0.0 1e-19 70.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM23742.1 - 7.8e-15 54.7 0.1 2.5e-14 53.1 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAM23742.1 - 7.6e-14 51.3 0.1 2.2e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II PAD_M PF08527.5 GAM23742.1 - 0.0024 17.2 0.0 0.0061 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) middle domain zf-C3Hc3H PF13891.1 GAM23743.1 - 1.3e-18 66.8 4.5 2.4e-18 65.9 3.1 1.4 1 0 0 1 1 1 1 Potential DNA-binding domain Pkinase PF00069.20 GAM23745.1 - 1.4e-72 244.0 0.0 2.1e-72 243.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23745.1 - 6e-41 140.2 0.0 9e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM23745.1 - 0.00016 20.7 0.0 0.00058 18.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 GAM23745.1 - 0.033 13.2 0.0 0.071 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM23745.1 - 0.035 13.8 0.0 0.081 12.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family SpoOE-like PF09388.5 GAM23746.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein RCC1 PF00415.13 GAM23747.1 - 1.9e-48 162.4 20.2 3.7e-11 43.0 0.3 8.3 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM23747.1 - 1.6e-32 110.3 40.7 1.7e-11 43.4 0.1 8.8 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.1 GAM23747.1 - 0.043 13.5 1.2 4.3 7.1 0.1 3.4 3 1 0 3 3 3 0 Galactose oxidase, central domain DUF1459 PF07312.6 GAM23747.1 - 6 6.8 6.1 3.3 7.6 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1459) Pkinase PF00069.20 GAM23749.1 - 7.3e-65 218.6 0.0 7.3e-65 218.6 0.0 3.4 4 1 1 5 5 5 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM23749.1 - 6.5e-31 107.3 0.0 6.5e-31 107.3 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase Laminin_EGF PF00053.19 GAM23750.1 - 1.9 8.4 21.4 5.1 7.1 3.5 2.5 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) ADK PF00406.17 GAM23751.1 - 2.1e-50 170.4 0.0 2.5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 GAM23751.1 - 8.5e-09 35.7 0.0 1.9e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM23751.1 - 4.2e-08 33.1 0.0 9.4e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM23751.1 - 7.5e-08 33.2 0.0 1e-07 32.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 GAM23751.1 - 3e-05 23.4 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 GAM23751.1 - 0.00027 20.1 0.0 0.00027 20.1 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.24 GAM23751.1 - 0.047 13.9 0.1 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 GAM23752.1 - 5.2e-39 133.4 0.0 7.1e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM23752.1 - 2.4e-06 27.6 0.4 1.9e-05 24.7 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM23752.1 - 7.8e-05 22.8 0.0 0.0056 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM23752.1 - 9.3e-05 23.2 0.0 0.00021 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 GAM23752.1 - 0.00015 21.4 0.0 0.00038 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAM23752.1 - 0.00017 20.7 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 GAM23752.1 - 0.00034 19.6 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 GAM23752.1 - 0.00072 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAM23752.1 - 0.00087 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 GAM23752.1 - 0.00089 19.0 0.0 0.014 15.1 0.0 2.0 1 1 1 2 2 2 1 Archaeal ATPase Bac_DnaA PF00308.13 GAM23752.1 - 0.00097 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.12 GAM23752.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 GAM23752.1 - 0.0013 17.5 0.0 0.0017 17.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 GAM23752.1 - 0.003 17.6 0.0 0.0053 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 GAM23752.1 - 0.013 15.8 0.1 0.037 14.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 GAM23752.1 - 0.017 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 GAM23752.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 GAM23752.1 - 0.05 13.4 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM23752.1 - 0.051 13.2 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 GAM23752.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 GAM23752.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Part of AAA domain Rad17 PF03215.10 GAM23752.1 - 0.079 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 GAM23752.1 - 0.085 12.4 0.1 0.17 11.4 0.0 1.4 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 GAM23752.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 GAM23752.1 - 0.11 11.1 0.0 0.17 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinesin motor domain KAP_NTPase PF07693.9 GAM23752.1 - 0.12 11.3 0.0 0.35 9.8 0.0 1.4 1 1 1 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 GAM23752.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain CoA_transf_3 PF02515.12 GAM23753.1 - 6.3e-55 185.3 0.1 8.6e-55 184.9 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III DUF1528 PF07515.6 GAM23753.1 - 0.046 13.7 0.1 0.087 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1528) LRR_8 PF13855.1 GAM23754.1 - 1.3e-05 24.8 1.2 1.3e-05 24.8 0.8 5.5 4 2 2 6 6 6 1 Leucine rich repeat DUF605 PF04652.11 GAM23754.1 - 8.9 5.6 9.4 12 5.1 6.5 1.1 1 0 0 1 1 1 0 Vta1 like RVT_1 PF00078.22 GAM23755.1 - 4.2e-35 121.0 0.0 6.4e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-oxoacid_dh PF00198.18 GAM23756.1 - 5e-84 281.1 0.0 7.8e-84 280.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM23756.1 - 8e-20 70.2 0.0 1.6e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 GAM23756.1 - 5.9e-12 45.0 0.1 1.9e-11 43.4 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Ribosomal_60s PF00428.14 GAM23756.1 - 0.00018 21.8 9.5 0.047 14.1 1.2 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein HlyD_3 PF13437.1 GAM23756.1 - 0.031 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF2782 PF11191.3 GAM23756.1 - 0.53 10.2 3.5 0.86 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) DUF3597 PF12200.3 GAM23756.1 - 3.1 8.2 7.8 13 6.2 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) MMR_HSR1 PF01926.18 GAM23757.1 - 5.2e-10 39.3 0.1 1.9e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM23757.1 - 1.9e-06 27.1 0.0 2.1e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAM23757.1 - 0.00015 22.2 0.4 0.016 15.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 GAM23757.1 - 0.0009 18.9 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM23757.1 - 0.0019 18.0 5.2 0.16 11.7 0.1 3.1 2 1 1 3 3 3 2 Dynamin family Septin PF00735.13 GAM23757.1 - 0.0027 16.7 0.0 0.0054 15.7 0.0 1.5 1 0 0 1 1 1 1 Septin Arch_ATPase PF01637.13 GAM23757.1 - 0.0052 16.5 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase Ras PF00071.17 GAM23757.1 - 0.0099 15.2 0.1 4.7 6.5 0.0 2.4 2 0 0 2 2 2 2 Ras family AAA_17 PF13207.1 GAM23757.1 - 0.014 16.2 0.0 0.079 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 GAM23757.1 - 0.019 14.2 0.3 0.16 11.2 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 GAM23757.1 - 0.035 14.3 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter CobU PF02283.11 GAM23757.1 - 0.08 12.3 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.1 GAM23757.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM23757.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L28 PF00830.14 GAM23758.1 - 2.8e-19 68.7 0.2 5.5e-19 67.7 0.0 1.6 1 1 1 2 2 2 1 Ribosomal L28 family ApbA PF02558.11 GAM23758.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MIF4G PF02854.14 GAM23759.1 - 3.6e-32 111.4 20.7 8.2e-15 54.7 2.2 4.0 3 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 GAM23759.1 - 6.6e-08 32.5 2.3 6.6e-08 32.5 1.6 4.7 4 0 0 4 4 4 2 Up-frameshift suppressor 2 DUF3810 PF12725.2 GAM23759.1 - 3.2 6.5 9.4 0.071 11.9 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) NAC PF01849.13 GAM23760.1 - 4.4e-17 61.3 0.0 6.5e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 NAC domain Ded_cyto PF06920.8 GAM23760.1 - 0.089 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Dedicator of cytokinesis cobW PF02492.14 GAM23761.1 - 1.2e-50 171.4 0.3 1.6e-50 170.9 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 GAM23761.1 - 4.5e-18 64.7 0.0 7.2e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 GAM23761.1 - 0.01 15.9 0.3 0.052 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 GAM23761.1 - 0.012 15.1 0.6 0.03 13.8 0.4 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 GAM23761.1 - 0.015 14.1 0.1 0.036 12.9 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3901 PF13040.1 GAM23761.1 - 0.02 14.1 0.5 0.052 12.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) Arch_ATPase PF01637.13 GAM23761.1 - 0.037 13.7 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 GAM23761.1 - 0.049 13.5 1.0 0.27 11.2 0.7 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 GAM23761.1 - 0.073 13.5 0.7 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 GAM23761.1 - 0.093 12.3 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 GAM23761.1 - 0.1 11.7 0.1 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 GAM23761.1 - 0.29 11.4 2.1 2.3 8.4 1.4 2.2 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 GAM23761.1 - 1.4 9.1 9.1 29 4.8 6.3 2.3 1 1 0 1 1 1 0 AAA domain Yip1 PF04893.12 GAM23762.1 - 5.7e-14 51.9 10.0 5.7e-14 51.9 6.9 1.5 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.10 GAM23762.1 - 0.041 13.0 9.4 0.1 11.7 6.5 1.7 1 1 0 1 1 1 0 YIF1 DUF1700 PF08006.6 GAM23762.1 - 6.4 6.0 9.3 3.1 7.0 4.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Glutaredoxin PF00462.19 GAM23764.1 - 0.00046 20.1 0.0 0.00095 19.1 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin DUF3186 PF11382.3 GAM23764.1 - 0.018 14.1 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Guanylate_kin PF00625.16 GAM23764.1 - 0.057 12.8 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase Rft-1 PF04506.8 GAM23765.1 - 9e-83 278.4 26.5 5e-81 272.7 18.4 2.0 1 1 0 1 1 1 1 Rft protein RasGAP PF00616.14 GAM23766.1 - 4.1e-15 55.9 0.0 2.1e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase PrgU PF09627.5 GAM23766.1 - 0.063 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 PrgU-like protein Herpes_capsid PF06112.6 GAM23766.1 - 2.5 8.1 10.0 3.9 7.4 6.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein AIG1 PF04548.11 GAM23767.1 - 8.2e-23 80.6 0.0 1.8e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAM23767.1 - 7.5e-10 38.7 0.6 2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM23767.1 - 1.4e-05 24.3 0.1 3.4e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 GAM23767.1 - 0.00026 20.1 0.2 0.0011 18.0 0.1 2.0 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.18 GAM23767.1 - 0.00046 20.0 4.9 0.025 14.3 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.1 GAM23767.1 - 0.0026 17.7 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.7 GAM23767.1 - 0.0041 16.2 0.1 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region T2SE PF00437.15 GAM23767.1 - 0.0045 15.9 0.1 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 GAM23767.1 - 0.011 14.6 0.1 0.044 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.13 GAM23767.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 GAM23767.1 - 0.018 15.3 0.1 0.076 13.3 0.0 2.0 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 GAM23767.1 - 0.062 12.7 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 GAM23767.1 - 0.065 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 GAM23767.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 GAM23767.1 - 0.099 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Miro PF08477.8 GAM23767.1 - 0.099 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein GATA PF00320.22 GAM23768.1 - 5.5e-14 51.2 3.1 5.5e-14 51.2 2.1 1.9 2 0 0 2 2 2 1 GATA zinc finger Sad1_UNC PF07738.8 GAM23769.1 - 3.1e-33 114.4 0.6 3.1e-33 114.4 0.4 3.1 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal MpPF26 PF07666.6 GAM23769.1 - 7.5 6.4 8.0 1.3 8.9 0.3 2.5 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF2404 PF10296.4 GAM23771.1 - 8.8e-08 32.1 0.0 8.8e-08 32.1 0.0 2.4 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) DUF2681 PF10883.3 GAM23771.1 - 0.0037 17.4 2.1 0.0037 17.4 1.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2681) Serinc PF03348.10 GAM23771.1 - 0.07 11.8 7.0 0.16 10.6 0.1 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF2852 PF11014.3 GAM23771.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Ctr PF04145.10 GAM23771.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.4 2 1 0 2 2 2 0 Ctr copper transporter family DUF3735 PF12537.3 GAM23771.1 - 0.13 12.3 0.1 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) TFIIA PF03153.8 GAM23771.1 - 0.76 9.6 23.9 1.3 8.8 9.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1917 PF08939.5 GAM23771.1 - 1.3 8.7 5.1 0.73 9.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) DUF4199 PF13858.1 GAM23771.1 - 4.6 7.1 7.0 0.54 10.1 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) PA14 PF07691.7 GAM23773.1 - 4.6e-13 49.0 0.0 8.3e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM23773.1 - 1e-10 41.2 30.8 2.8e-08 33.4 0.5 12.3 12 0 0 12 12 12 6 Dictyostelium (slime mold) repeat nsp9 PF08710.5 GAM23774.1 - 0.034 14.3 0.1 0.061 13.4 0.0 1.5 2 0 0 2 2 2 0 nsp9 replicase Pex14_N PF04695.8 GAM23774.1 - 8.6 6.4 12.8 3.3e+02 1.2 8.9 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Keratin_assoc PF09775.4 GAM23775.1 - 4.3e-25 87.7 0.4 5.2e-25 87.5 0.3 1.1 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 Nucleos_tra2_N PF01773.15 GAM23775.1 - 0.15 12.4 4.7 0.17 12.2 0.9 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus Flp_Fap PF04964.9 GAM23775.1 - 0.19 11.3 2.5 0.87 9.2 0.0 2.7 3 0 0 3 3 3 0 Flp/Fap pilin component Peptidase_M50B PF13398.1 GAM23775.1 - 0.25 10.7 7.5 0.066 12.5 3.1 1.5 1 1 0 1 1 1 0 Peptidase M50B-like DUF606 PF04657.8 GAM23775.1 - 0.34 10.9 7.4 0.26 11.3 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF606 ABC2_membrane_3 PF12698.2 GAM23775.1 - 0.39 9.7 10.3 0.5 9.3 7.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein SHR3_chaperone PF08229.6 GAM23775.1 - 0.43 9.4 4.5 0.64 8.9 0.4 2.0 1 1 1 2 2 2 0 ER membrane protein SH3 DUF2892 PF11127.3 GAM23775.1 - 0.71 9.7 4.1 2.1 8.2 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2892) RseC_MucC PF04246.7 GAM23775.1 - 1.9 8.0 4.1 4.1 6.9 1.2 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC YjgP_YjgQ PF03739.9 GAM23775.1 - 5 5.7 9.3 0.28 9.8 2.9 1.4 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family FNIP PF05725.7 GAM23777.1 - 8.9e-67 220.8 32.8 1.7e-11 43.9 0.0 10.4 8 3 0 10 10 10 8 FNIP Repeat DUF1769 PF08588.5 GAM23777.1 - 0.0024 17.7 7.7 1.5 8.8 0.1 6.4 4 3 3 7 7 7 1 Protein of unknown function (DUF1769) F-box PF00646.28 GAM23777.1 - 0.21 11.2 5.6 0.16 11.6 0.5 2.9 3 0 0 3 3 3 0 F-box domain CK_II_beta PF01214.13 GAM23778.1 - 1.9e-78 262.2 0.0 2.3e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit zf-TFIIB PF13453.1 GAM23778.1 - 0.12 11.5 0.8 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF1765 PF08578.5 GAM23779.1 - 1.6e-23 83.1 0.5 1.6e-23 83.1 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) ACC_central PF08326.7 GAM23780.1 - 1.9e-171 571.7 5.2 2.4e-171 571.3 3.6 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 GAM23780.1 - 7.7e-155 515.9 0.0 1.2e-154 515.3 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAM23780.1 - 1.5e-49 168.1 0.0 2.9e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAM23780.1 - 3.4e-24 85.0 0.0 7.6e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM23780.1 - 2e-19 69.5 0.0 5.5e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAM23780.1 - 9.3e-12 45.0 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 GAM23780.1 - 2.1e-11 43.3 0.1 4.6e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 GAM23780.1 - 0.00013 21.4 0.1 0.00043 19.7 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAM23780.1 - 0.0024 17.2 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 GAM23780.1 - 0.0051 16.6 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain NAAA-beta PF15508.1 GAM23780.1 - 0.034 14.4 0.3 0.27 11.5 0.2 2.6 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3829 PF12889.2 GAM23780.1 - 0.051 12.7 8.2 1.2 8.2 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) BTG PF07742.7 GAM23781.1 - 0.023 14.2 0.2 0.085 12.3 0.0 2.0 2 0 0 2 2 2 0 BTG family LPP PF04728.8 GAM23781.1 - 0.033 13.9 0.6 0.12 12.1 0.4 2.1 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Nexin_C PF08628.7 GAM23781.1 - 0.057 13.5 0.3 0.057 13.5 0.2 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal Apolipoprotein PF01442.13 GAM23781.1 - 0.08 12.4 9.8 0.045 13.2 3.8 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain SmpA_OmlA PF04355.8 GAM23781.1 - 0.09 12.4 3.0 0.19 11.3 1.5 2.0 1 1 0 1 1 1 0 SmpA / OmlA family DUF822 PF05687.8 GAM23781.1 - 0.58 10.4 13.4 1.3 9.4 1.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF822) A2M_recep PF07677.9 GAM23781.1 - 3.7 7.7 6.5 3.8 7.7 0.5 2.5 2 1 0 2 2 2 0 A-macroglobulin receptor HECT PF00632.20 GAM23782.1 - 4.1e-61 206.8 0.2 1e-60 205.6 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PH PF00169.24 GAM23782.1 - 6.4e-19 68.0 1.0 5.9e-18 64.9 0.6 2.9 2 0 0 2 2 2 1 PH domain SPRY PF00622.23 GAM23782.1 - 2.7e-17 63.0 0.2 8.5e-17 61.4 0.1 1.9 1 0 0 1 1 1 1 SPRY domain PH_9 PF15410.1 GAM23782.1 - 1.4e-09 38.0 1.6 4.5e-09 36.4 1.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 GAM23782.1 - 0.00058 20.1 0.6 0.0019 18.4 0.4 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Sporozoite_P67 PF05642.6 GAM23783.1 - 6.9 4.4 11.8 8.3 4.1 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FNIP PF05725.7 GAM23784.1 - 0.00068 19.5 0.0 0.0029 17.5 0.0 2.1 1 1 1 2 2 2 1 FNIP Repeat DUF2576 PF10845.3 GAM23784.1 - 1.4 8.1 4.0 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) FNIP PF05725.7 GAM23785.1 - 1.5e-05 24.7 0.8 0.0047 16.8 0.0 3.7 4 0 0 4 4 4 1 FNIP Repeat DUF2661 PF10860.3 GAM23785.1 - 0.1 12.8 0.1 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) Exo70 PF03081.10 GAM23787.1 - 0.0022 16.8 0.2 0.0037 16.1 0.1 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit LRR_6 PF13516.1 GAM23788.1 - 0.0012 18.7 0.2 6.5 7.1 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich repeat FNIP PF05725.7 GAM23789.1 - 2.2e-13 49.9 6.9 7.7e-07 28.9 0.1 7.0 6 1 1 7 7 7 5 FNIP Repeat Exo70 PF03081.10 GAM23791.1 - 0.084 11.6 0.1 0.17 10.6 0.0 1.5 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Nucleoplasmin PF03066.10 GAM23791.1 - 1.2 8.6 6.0 2.2 7.8 4.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin FNIP PF05725.7 GAM23792.1 - 6e-15 54.9 0.6 7.9e-08 32.1 0.2 2.4 2 0 0 2 2 2 2 FNIP Repeat FNIP PF05725.7 GAM23793.1 - 2.8e-48 161.6 13.6 1.7e-15 56.6 0.4 5.2 3 1 3 6 6 6 6 FNIP Repeat TIP41 PF04176.8 GAM23794.1 - 9.8e-63 210.6 0.0 1.3e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family PA14 PF07691.7 GAM23795.1 - 2.2e-09 37.0 0.0 4.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM23795.1 - 0.00012 21.8 33.1 0.0005 19.8 7.2 12.7 13 2 0 13 13 13 6 Dictyostelium (slime mold) repeat Zip PF02535.17 GAM23796.1 - 0.027 13.4 3.1 0.027 13.4 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1593 PF07632.6 GAM23796.1 - 0.054 12.8 1.5 0.057 12.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) SelP_N PF04592.9 GAM23796.1 - 0.1 11.9 10.2 0.11 11.8 7.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 GAM23796.1 - 0.54 8.4 8.4 0.51 8.5 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Bmp PF02608.9 GAM23797.1 - 5.3e-21 74.6 1.7 6.6e-21 74.3 1.2 1.0 1 0 0 1 1 1 1 Basic membrane protein DUF3411 PF11891.3 GAM23797.1 - 0.088 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3411) 7tm_3 PF00003.17 GAM23798.1 - 3.3e-36 124.8 16.2 4.3e-36 124.4 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3481 PF11980.3 GAM23798.1 - 1.4 8.7 5.5 15 5.4 2.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3481) Claudin_3 PF06653.6 GAM23798.1 - 8.8 6.0 16.5 0.024 14.3 2.8 2.6 2 1 0 3 3 3 0 Tight junction protein, Claudin-like 7tm_3 PF00003.17 GAM23799.1 - 1.2e-32 113.1 17.8 1.8e-32 112.5 12.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 GAM23799.1 - 1.9e-15 56.4 0.3 1.9e-15 56.4 0.2 2.6 2 1 1 3 3 3 1 Basic membrane protein UPF0542 PF15086.1 GAM23799.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF606 PF04657.8 GAM23799.1 - 1.1 9.3 18.2 0.25 11.4 1.0 3.1 3 1 0 3 3 3 0 Protein of unknown function, DUF606 Suf PF05843.9 GAM23800.1 - 6.6e-82 275.3 0.1 6.6e-82 275.3 0.1 6.6 3 1 2 6 6 6 1 Suppressor of forked protein (Suf) HAT PF02184.11 GAM23800.1 - 2.8e-07 30.1 0.3 0.018 14.7 0.0 2.8 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 GAM23800.1 - 1.8e-06 28.0 0.0 0.077 13.6 0.0 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM23800.1 - 0.0003 21.3 0.0 1.5 9.6 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM23800.1 - 0.0023 17.7 0.6 0.79 9.7 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM23800.1 - 0.0033 17.7 0.0 0.0033 17.7 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM23800.1 - 0.004 16.7 0.1 0.022 14.3 0.0 2.3 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.1 GAM23800.1 - 0.0079 16.5 2.4 13 6.5 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM23800.1 - 0.29 11.4 2.7 1.7 9.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LIM PF00412.17 GAM23801.1 - 1.5e-09 37.7 5.4 2.9e-09 36.8 3.8 1.5 1 0 0 1 1 1 1 LIM domain OTU PF02338.14 GAM23802.1 - 9.7e-22 77.8 0.2 9.7e-22 77.8 0.2 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAM23802.1 - 1.5e-06 27.7 2.1 0.038 13.3 0.1 2.8 1 1 1 2 2 2 2 Peptidase C65 Otubain EF-hand_1 PF00036.27 GAM23803.1 - 1.8e-19 67.4 4.4 7.8e-06 24.8 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM23803.1 - 1.6e-18 66.5 1.3 8.6e-09 35.4 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM23803.1 - 1.1e-15 55.9 1.8 4.2e-05 23.0 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 GAM23803.1 - 4.9e-11 42.0 7.1 0.00017 21.1 0.8 4.8 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 GAM23803.1 - 6.9e-08 31.4 10.6 0.00025 20.2 0.0 4.6 5 1 0 5 5 5 3 EF hand EF-hand_9 PF14658.1 GAM23803.1 - 4.2e-05 23.3 0.1 0.001 18.9 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 GAM23803.1 - 0.0053 16.7 0.2 0.96 9.5 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region M16C_assoc PF08367.6 GAM23803.1 - 0.058 12.2 0.3 0.058 12.2 0.2 1.7 2 0 0 2 2 2 0 Peptidase M16C associated EF-hand_2 PF09068.6 GAM23803.1 - 0.062 13.3 0.1 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_like PF09279.6 GAM23803.1 - 0.083 12.9 6.4 0.54 10.3 0.4 2.7 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Dockerin_1 PF00404.13 GAM23803.1 - 1.6 8.5 3.6 4 7.3 0.7 2.5 2 0 0 2 2 2 0 Dockerin type I repeat UPF0220 PF05255.6 GAM23804.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF3149 PF11346.3 GAM23804.1 - 0.7 9.4 4.3 1.2 8.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Chromo PF00385.19 GAM23806.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain TIG PF01833.19 GAM23807.1 - 2e-21 75.7 14.4 3.9e-08 33.1 2.1 3.7 3 0 0 3 3 3 3 IPT/TIG domain DNase_II PF03265.10 GAM23807.1 - 7.6e-19 67.8 0.6 5.6e-10 38.7 0.9 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II PGM_PMM_I PF02878.11 GAM23808.1 - 6.1e-29 100.2 0.0 1.7e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 GAM23808.1 - 2.8e-23 82.2 0.0 5.8e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 GAM23808.1 - 2.5e-17 62.9 0.0 5e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 GAM23808.1 - 4.2e-08 33.0 0.1 1.4e-07 31.4 0.1 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1682 PF07946.9 GAM23809.1 - 4.7e-77 258.9 5.5 6.5e-77 258.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF912 PF06024.7 GAM23809.1 - 0.23 11.5 3.6 0.35 10.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4557 PF15101.1 GAM23809.1 - 1.4 8.6 10.0 7.8 6.2 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) zf-RING_2 PF13639.1 GAM23810.1 - 2.5e-05 24.0 10.0 2.5e-05 24.0 6.9 6.0 5 2 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.1 GAM23810.1 - 0.00029 20.4 9.8 0.00029 20.4 6.8 7.4 6 3 0 6 6 6 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM23810.1 - 0.0042 17.0 7.5 0.0042 17.0 5.2 7.3 6 4 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM23810.1 - 0.0045 16.6 10.0 0.0045 16.6 6.9 7.5 6 3 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) C2 PF00168.25 GAM23811.1 - 1.3e-15 57.0 0.4 5.4e-15 55.0 0.2 2.0 2 0 0 2 2 2 1 C2 domain zf-RING_5 PF14634.1 GAM23811.1 - 0.0056 16.3 7.4 0.014 15.1 5.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM23811.1 - 0.56 9.9 11.5 0.069 12.8 4.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L13e PF01294.13 GAM23812.1 - 1.3e-63 213.7 8.1 1.8e-63 213.2 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e D-ser_dehydrat PF14031.1 GAM23813.1 - 8.2e-19 67.5 0.0 4.7e-18 65.1 0.0 2.2 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 GAM23813.1 - 2.8e-16 59.7 0.0 4.1e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain SapB_1 PF05184.10 GAM23814.1 - 0.024 14.4 0.8 0.085 12.7 0.5 2.0 1 0 0 1 1 1 0 Saposin-like type B, region 1 Ran-binding PF05508.6 GAM23814.1 - 0.066 12.1 0.2 0.079 11.8 0.1 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF3877 PF12993.2 GAM23814.1 - 0.074 12.6 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4511 PF14974.1 GAM23814.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) SapB_2 PF03489.12 GAM23814.1 - 0.22 11.5 2.2 16 5.6 0.2 3.1 2 1 0 2 2 2 0 Saposin-like type B, region 2 APC_CDC26 PF10471.4 GAM23815.1 - 1.5 9.6 8.2 1.3 9.7 1.3 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Ras PF00071.17 GAM23816.1 - 6.9e-50 168.5 0.0 8.3e-50 168.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23816.1 - 3.2e-15 56.6 0.0 5.3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM23816.1 - 6.2e-07 28.8 0.0 8.4e-07 28.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM23816.1 - 0.042 12.9 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-C3HC4_2 PF13923.1 GAM23817.1 - 0.00098 19.0 0.5 0.0024 17.8 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ta0938 PF11494.3 GAM23817.1 - 0.022 14.8 0.2 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 Ta0938 zf-RING_2 PF13639.1 GAM23817.1 - 0.054 13.3 1.6 0.21 11.4 1.1 1.9 1 1 0 1 1 1 0 Ring finger domain DUF2619 PF10942.3 GAM23817.1 - 0.067 13.1 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) PLAC9 PF15205.1 GAM23817.1 - 0.11 12.8 0.1 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 Placenta-specific protein 9 DUF2779 PF11074.3 GAM23817.1 - 0.75 9.8 5.0 4.2 7.4 2.9 2.6 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) Xpo1 PF08389.7 GAM23818.1 - 0.0013 18.6 2.5 0.0024 17.7 0.4 2.5 2 0 0 2 2 2 1 Exportin 1-like protein SR-25 PF10500.4 GAM23818.1 - 0.0027 17.2 1.3 0.0027 17.2 0.9 2.9 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein UCH PF00443.24 GAM23819.1 - 1.5e-49 168.5 9.2 1.5e-49 168.5 6.3 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM23819.1 - 2.6e-21 76.3 13.4 5.5e-21 75.2 6.7 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PH PF00169.24 GAM23821.1 - 3.9e-07 30.2 0.1 9.2e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 PH domain PH_6 PF15406.1 GAM23821.1 - 4.4e-05 23.4 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM23821.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 GAM23821.1 - 0.0018 18.5 1.0 0.0064 16.7 0.7 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 GAM23821.1 - 0.015 15.1 0.0 0.67 9.8 0.0 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Chorion_3 PF05387.6 GAM23821.1 - 0.026 13.9 10.5 0.034 13.5 7.3 1.2 1 0 0 1 1 1 0 Chorion family 3 PH_3 PF14593.1 GAM23821.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF2383 PF09537.5 GAM23822.1 - 0.18 12.0 17.9 0.14 12.4 2.3 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF2383) LMSTEN PF07988.7 GAM23822.1 - 0.39 10.0 0.1 0.39 10.0 0.0 4.0 4 0 0 4 4 4 0 LMSTEN motif DUF1818 PF08848.6 GAM23822.1 - 9.7 6.2 11.1 0.59 10.2 2.2 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF1818) Sulfotransfer_2 PF03567.9 GAM23823.1 - 4.3e-11 42.9 0.1 2.2e-09 37.4 0.1 2.4 1 1 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM23823.1 - 1.9e-07 30.1 1.7 7.9e-06 24.7 1.2 2.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase G-alpha PF00503.15 GAM23824.1 - 8.2e-108 360.5 23.3 1e-107 360.2 15.9 1.3 1 1 0 1 1 1 1 G-protein alpha subunit PH PF00169.24 GAM23824.1 - 1.3e-13 51.0 0.4 1.3e-13 51.0 0.3 2.4 3 0 0 3 3 3 1 PH domain Arf PF00025.16 GAM23824.1 - 3.5e-12 45.9 1.8 2.2e-08 33.5 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family PKI PF02827.11 GAM23824.1 - 0.038 14.0 2.4 0.097 12.7 1.6 1.7 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Miro PF08477.8 GAM23824.1 - 0.072 13.5 1.0 2.5 8.6 0.0 3.4 4 0 0 4 4 4 0 Miro-like protein ProRS-C_1 PF09180.6 GAM23825.1 - 1.1e-21 76.4 0.9 3.8e-21 74.7 0.6 2.0 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 GAM23825.1 - 2e-20 73.0 0.3 7.4e-20 71.2 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM23825.1 - 3.8e-15 55.5 0.0 9.4e-15 54.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain AstB PF04996.7 GAM23825.1 - 0.046 12.5 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Succinylarginine dihydrolase HNH PF01844.18 GAM23825.1 - 0.1 12.4 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease OPA3 PF07047.7 GAM23826.1 - 1.3e-29 102.7 0.4 1.6e-29 102.3 0.3 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) His_Phos_2 PF00328.17 GAM23826.1 - 0.012 14.9 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Allexi_40kDa PF05549.6 GAM23826.1 - 0.016 14.5 0.2 0.021 14.1 0.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Atg14 PF10186.4 GAM23826.1 - 0.024 13.6 0.1 0.029 13.3 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPD52 PF04201.10 GAM23826.1 - 0.024 14.3 0.4 0.043 13.5 0.3 1.4 1 0 0 1 1 1 0 Tumour protein D52 family bZIP_2 PF07716.10 GAM23826.1 - 0.25 11.1 4.1 0.43 10.4 2.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper zf-HIT PF04438.11 GAM23827.1 - 3.8e-09 36.0 10.6 6.8e-09 35.2 7.4 1.4 1 0 0 1 1 1 1 HIT zinc finger Cluap1 PF10234.4 GAM23827.1 - 0.15 11.2 1.8 0.19 10.9 1.2 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 zf-MYND PF01753.13 GAM23827.1 - 2.5 8.0 9.8 0.68 9.8 4.5 1.9 2 1 0 2 2 2 0 MYND finger AMP-binding PF00501.23 GAM23828.1 - 5.1e-24 84.4 0.0 9.1e-24 83.5 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme DUF3426 PF11906.3 GAM23828.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) N2227 PF07942.7 GAM23830.1 - 3.1e-92 308.3 0.2 3.9e-92 308.0 0.2 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 GAM23830.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23830.1 - 0.018 15.4 0.1 0.061 13.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23830.1 - 0.042 14.3 0.0 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Complex1_LYR_2 PF13233.1 GAM23831.1 - 4.4e-06 27.1 0.1 6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM23831.1 - 3.6e-05 23.4 0.0 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM23831.1 - 0.001 19.2 0.2 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 Complex1_LYR-like SPAN-X PF07458.7 GAM23832.1 - 0.1 12.8 0.2 0.17 12.1 0.2 1.5 1 1 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Septin PF00735.13 GAM23834.1 - 1.4e-05 24.2 0.0 3.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 GAM23834.1 - 0.0013 17.9 1.2 0.029 13.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM23834.1 - 0.034 14.0 0.1 0.098 12.6 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1 PF01926.18 GAM23835.1 - 0.0026 17.7 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM23835.1 - 0.027 14.8 0.0 0.048 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM23835.1 - 0.029 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 GAM23835.1 - 0.032 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3980 PF13140.1 GAM23835.1 - 0.046 14.0 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) PRANC PF09372.5 GAM23835.1 - 0.047 13.6 2.9 0.081 12.9 1.2 2.0 2 0 0 2 2 2 0 PRANC domain AAA_22 PF13401.1 GAM23835.1 - 0.052 13.6 0.0 0.27 11.3 0.0 2.2 1 1 2 3 3 3 0 AAA domain AAA_17 PF13207.1 GAM23835.1 - 0.086 13.6 0.0 0.24 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.18 GAM23836.1 - 0.0078 15.5 1.2 0.016 14.6 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin family AAA_29 PF13555.1 GAM23836.1 - 0.041 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sugarporin_N PF11471.3 GAM23837.1 - 0.12 12.0 1.1 0.35 10.5 0.7 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension AAA_11 PF13086.1 GAM23838.1 - 4.9e-71 239.0 0.1 4.9e-71 239.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 GAM23838.1 - 1.3e-55 187.8 0.0 4.6e-55 186.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM23838.1 - 2.2e-12 46.5 0.1 1.3e-10 40.8 0.0 3.1 3 1 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 GAM23838.1 - 2.2e-08 33.9 0.5 0.0064 16.0 0.0 2.9 3 1 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 GAM23838.1 - 3.8e-07 29.8 0.0 0.0036 16.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 GAM23838.1 - 0.00011 21.2 0.3 0.12 11.2 0.0 2.5 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 GAM23838.1 - 0.0035 17.4 0.1 0.13 12.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM23838.1 - 0.0055 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.16 GAM23838.1 - 0.011 15.0 1.0 0.36 10.0 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 GAM23838.1 - 0.02 14.1 0.1 0.81 8.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 GAM23838.1 - 0.028 13.8 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 GAM23838.1 - 0.098 12.0 0.2 0.46 9.8 0.1 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM23838.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ComX PF05952.7 GAM23838.1 - 0.1 12.1 0.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 Bacillus competence pheromone ComX RINGv PF12906.2 GAM23839.1 - 1e-05 25.4 14.7 1e-05 25.4 10.2 3.4 3 1 0 3 3 3 1 RING-variant domain zf-C3HC4_3 PF13920.1 GAM23841.1 - 1.1e-13 50.6 12.9 1.8e-13 49.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cbl_N2 PF02761.9 GAM23841.1 - 4.4e-08 33.0 0.1 1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.19 GAM23841.1 - 5.4e-08 32.5 0.0 2.1e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 SH2 domain zf-C3HC4_2 PF13923.1 GAM23841.1 - 1.5e-05 24.9 15.5 2.9e-05 23.9 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 GAM23841.1 - 0.019 14.4 6.1 0.056 12.9 4.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 GAM23841.1 - 0.098 12.4 14.8 0.18 11.5 10.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Cbl_N3 PF02762.9 GAM23841.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain zf-RING_2 PF13639.1 GAM23841.1 - 0.18 11.6 13.5 0.38 10.6 9.4 1.6 1 0 0 1 1 1 0 Ring finger domain PP2C_2 PF13672.1 GAM23843.1 - 8e-06 25.4 2.1 4.2e-05 23.0 0.1 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C DEP PF00610.16 GAM23843.1 - 1.4e-05 24.7 0.0 4.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SpoIIE PF07228.7 GAM23843.1 - 0.038 13.6 0.1 0.49 10.0 0.0 2.4 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DAP3 PF10236.4 GAM23844.1 - 3.7e-46 157.4 0.3 2.4e-45 154.8 0.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 GAM23844.1 - 0.00033 20.3 0.0 0.0018 17.9 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 GAM23844.1 - 0.046 13.8 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM23844.1 - 0.077 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 GAM23844.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 GAM23845.1 - 8.3e-08 33.0 1.0 2.6e-07 31.4 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM23845.1 - 1.6e-06 28.4 0.2 1.6e-06 28.4 0.2 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM23845.1 - 0.00024 20.2 0.1 0.00095 18.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 GAM23845.1 - 0.00063 19.6 0.1 0.0035 17.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 GAM23845.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM23845.1 - 0.0062 16.6 0.1 0.11 12.7 0.1 3.1 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 GAM23845.1 - 0.0084 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 GAM23845.1 - 0.028 13.6 0.0 0.075 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Phage-tail_3 PF13550.1 GAM23845.1 - 0.056 13.2 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative phage tail protein APS_kinase PF01583.15 GAM23845.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.13 GAM23845.1 - 0.11 12.0 1.9 0.39 10.2 0.2 2.6 2 2 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 GAM23845.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM23845.1 - 0.68 10.2 7.8 0.17 12.2 1.0 2.7 2 1 0 2 2 2 0 ABC transporter SH3_1 PF00018.23 GAM23846.1 - 4.1e-15 54.9 0.2 1e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM23846.1 - 3.9e-14 51.8 0.0 2e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 GAM23846.1 - 5.7e-14 51.4 0.5 1.1e-13 50.5 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain Cofilin_ADF PF00241.15 GAM23846.1 - 3.6e-11 43.0 0.0 7.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PAT1 PF09770.4 GAM23846.1 - 5.7 5.0 43.8 7.3 4.6 30.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 cwf18 PF08315.7 GAM23847.1 - 0.023 15.1 0.8 0.033 14.6 0.5 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF2066 PF09839.4 GAM23847.1 - 0.088 11.9 0.9 0.13 11.3 0.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) MSA-2c PF12238.3 GAM23847.1 - 0.73 9.4 7.0 1 9.0 4.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c SR-25 PF10500.4 GAM23847.1 - 2.2 7.6 13.3 3 7.2 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_9 PF14580.1 GAM23848.1 - 1.3e-58 197.3 1.0 1.6e-58 197.1 0.7 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 GAM23848.1 - 3.6e-14 51.9 16.3 2.4e-06 27.0 4.6 3.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM23848.1 - 1.4e-09 37.5 13.0 1.4e-06 27.9 1.6 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 GAM23848.1 - 0.00049 19.7 13.5 2.8 8.3 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 GAM23848.1 - 0.014 15.3 13.9 13 6.2 0.0 5.3 4 1 1 5 5 5 0 Leucine Rich repeat LRR_7 PF13504.1 GAM23848.1 - 0.03 14.4 10.5 53 4.6 0.8 5.3 5 0 0 5 5 5 0 Leucine rich repeat VWA_2 PF13519.1 GAM23849.1 - 2.5e-18 66.7 0.0 3.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain LRR_4 PF12799.2 GAM23850.1 - 2.2e-28 97.3 26.1 4.4e-08 32.5 2.1 6.3 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM23850.1 - 1.6e-20 72.6 17.3 1.9e-09 37.1 1.2 3.8 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 GAM23850.1 - 1.2e-16 58.1 22.5 0.25 11.5 0.0 9.7 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 GAM23850.1 - 8.4e-15 52.3 19.4 3.2 8.3 0.0 9.3 9 0 0 9 9 9 6 Leucine rich repeat C2 PF00168.25 GAM23850.1 - 1.6e-13 50.2 0.0 3.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain LRR_6 PF13516.1 GAM23850.1 - 4.4e-07 29.2 25.1 0.98 9.6 0.4 9.2 9 1 0 9 9 9 3 Leucine Rich repeat PAT1 PF09770.4 GAM23850.1 - 1.4 7.1 13.0 2.1 6.5 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EGF_2 PF07974.8 GAM23851.1 - 5.2e-05 23.3 15.3 0.00011 22.2 10.6 1.6 1 0 0 1 1 1 1 EGF-like domain Toxin_2 PF00451.14 GAM23851.1 - 0.44 10.6 9.9 1.2 9.2 6.8 1.8 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 EGF_alliinase PF04863.8 GAM23851.1 - 6.4 6.8 8.1 20 5.2 4.2 2.7 2 1 0 2 2 2 0 Alliinase EGF-like domain Hydrolase_6 PF13344.1 GAM23853.1 - 2.8e-21 75.2 0.0 1.5e-20 72.9 0.0 2.2 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 GAM23853.1 - 4.1e-15 55.2 0.0 1.6e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 GAM23853.1 - 0.013 15.7 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM23853.1 - 0.03 14.7 0.1 0.22 11.9 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Myb_DNA-binding PF00249.26 GAM23855.1 - 0.016 15.2 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SUV3_C PF12513.3 GAM23856.1 - 2.1e-11 43.0 1.3 4e-11 42.1 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 GAM23856.1 - 4.2e-10 39.3 0.0 1.5e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Complex1_LYR PF05347.10 GAM23857.1 - 1.4e-13 50.3 0.1 1.8e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM23857.1 - 1.2e-11 44.6 0.0 1.6e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Rif1_N PF12231.3 GAM23857.1 - 0.055 12.4 0.1 0.055 12.4 0.1 1.0 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Chromo PF00385.19 GAM23858.1 - 4.3e-05 23.0 1.4 8.2e-05 22.2 1.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.14 GAM23858.1 - 0.0038 16.7 1.5 0.0095 15.4 1.0 1.7 1 0 0 1 1 1 1 AT hook motif CDC45 PF02724.9 GAM23858.1 - 0.072 11.1 11.5 0.094 10.7 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 GAM23858.1 - 0.097 10.5 10.6 0.1 10.5 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 GAM23858.1 - 3.2 7.0 19.5 3.6 6.8 13.5 1.1 1 0 0 1 1 1 0 Vta1 like Na_trans_assoc PF06512.8 GAM23858.1 - 4.2 7.2 13.9 6.6 6.6 9.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.5 GAM23858.1 - 6.9 5.6 22.4 9.8 5.1 15.5 1.2 1 0 0 1 1 1 0 BUD22 ABC_tran PF00005.22 GAM23859.1 - 9.7e-21 74.5 1.3 4.4e-14 52.9 0.0 2.7 3 0 0 3 3 3 2 ABC transporter Mitofilin PF09731.4 GAM23860.1 - 0.02 13.5 1.2 0.02 13.5 0.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PRP21_like_P PF12230.3 GAM23860.1 - 0.17 11.4 4.7 0.26 10.7 3.2 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein TFIIA PF03153.8 GAM23860.1 - 0.4 10.5 12.3 0.44 10.3 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 GAM23860.1 - 1.7 7.9 18.0 2.3 7.5 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 GAM23860.1 - 6.2 4.9 18.4 6.5 4.8 12.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CheZ PF04344.8 GAM23861.1 - 0.63 9.6 3.7 0.68 9.5 2.5 1.0 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Secretin_N_2 PF07655.8 GAM23861.1 - 1.3 9.4 26.7 1.5 9.2 18.5 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Eapp_C PF10238.4 GAM23861.1 - 3.4 7.5 15.7 3.9 7.3 10.9 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein PH_4 PF15404.1 GAM23861.1 - 4.2 6.8 6.5 4.4 6.8 4.5 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain DUF912 PF06024.7 GAM23861.1 - 4.4 7.4 16.2 5.4 7.1 11.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PIG-X PF08320.7 GAM23862.1 - 4e-20 72.0 2.9 1e-16 60.8 0.1 2.2 1 1 1 2 2 2 2 PIG-X / PBN1 Pkinase_Tyr PF07714.12 GAM23863.1 - 3.1e-62 210.0 0.0 4.4e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23863.1 - 3.5e-53 180.4 0.0 6.6e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 GAM23863.1 - 2e-09 36.9 0.3 0.0012 18.6 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat PsaN PF05479.6 GAM23863.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Ribosomal_60s PF00428.14 GAM23864.1 - 6.5e-24 84.1 17.7 8.3e-24 83.8 12.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 GAM23864.1 - 0.11 10.6 8.3 0.12 10.5 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Med3 PF11593.3 GAM23864.1 - 5.2 6.1 7.1 6.1 5.9 4.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal G-alpha PF00503.15 GAM23865.1 - 3e-106 355.3 4.6 3.6e-106 355.1 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM23865.1 - 4.6e-15 55.2 2.0 6.1e-11 41.8 0.5 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM23865.1 - 1e-05 24.8 0.2 0.0063 15.6 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM23865.1 - 0.041 13.3 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Halo_GVPC PF05465.8 GAM23865.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Miro PF08477.8 GAM23865.1 - 0.084 13.3 0.0 17 5.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein CGI-121 PF08617.5 GAM23866.1 - 0.0013 18.4 1.7 0.47 10.1 0.0 3.0 2 2 0 2 2 2 1 Kinase binding protein CGI-121 DUF713 PF05218.9 GAM23866.1 - 0.0033 17.1 3.5 0.0059 16.3 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF713) UPF0242 PF06785.6 GAM23866.1 - 0.016 13.8 5.8 0.027 13.1 4.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DivIC PF04977.10 GAM23866.1 - 0.051 13.0 11.4 0.35 10.3 0.3 3.5 3 1 1 4 4 4 0 Septum formation initiator ATG16 PF08614.6 GAM23866.1 - 0.062 13.1 11.1 0.052 13.3 4.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.4 GAM23866.1 - 0.083 11.1 7.0 0.051 11.8 3.3 1.7 2 0 0 2 2 2 0 Transmembrane protein AAA_13 PF13166.1 GAM23866.1 - 0.28 9.6 8.9 0.43 8.9 6.2 1.3 1 1 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 GAM23866.1 - 0.3 11.2 9.2 0.29 11.2 3.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.3 GAM23866.1 - 0.34 10.6 4.4 0.86 9.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF972 PF06156.8 GAM23866.1 - 0.36 11.1 9.4 10 6.5 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 GAM23866.1 - 0.4 10.4 14.1 0.12 12.0 4.8 3.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding RPW8 PF05659.6 GAM23866.1 - 0.43 10.1 6.1 7.5 6.0 1.0 3.0 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF848 PF05852.6 GAM23866.1 - 0.55 10.0 10.0 0.24 11.2 3.2 2.4 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF342 PF03961.8 GAM23866.1 - 1.3 7.3 8.7 0.76 8.1 4.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fez1 PF06818.10 GAM23866.1 - 1.4 8.8 8.9 2.5 8.0 6.2 1.5 1 1 0 1 1 1 0 Fez1 bZIP_1 PF00170.16 GAM23866.1 - 1.6 8.7 4.9 19 5.2 0.1 3.1 2 1 1 3 3 3 0 bZIP transcription factor DivIVA PF05103.8 GAM23866.1 - 2.6 8.0 11.9 0.16 12.0 1.2 2.9 1 1 2 3 3 3 0 DivIVA protein DUF3391 PF11871.3 GAM23866.1 - 4.6 7.4 6.4 4.9 7.3 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) TBPIP PF07106.8 GAM23866.1 - 7.2 6.1 12.7 3.8 7.0 6.2 2.2 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BLOC1_2 PF10046.4 GAM23866.1 - 7.9 6.6 10.2 1.4 9.1 1.8 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 GAM23866.1 - 9 5.8 12.5 17 4.9 6.8 2.4 2 1 0 2 2 2 0 IncA protein MCPsignal PF00015.16 GAM23866.1 - 9.1 5.7 9.9 2e+02 1.3 6.8 2.2 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Proteasome PF00227.21 GAM23867.1 - 2.7e-32 111.6 0.0 3.2e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Endonuclease_5 PF04493.9 GAM23868.1 - 2.5e-60 203.3 0.0 3.3e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 GAM23868.1 - 0.0061 15.6 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF99 SSP160 PF06933.6 GAM23868.1 - 1.3 6.9 12.9 1.8 6.4 9.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 GAM23868.1 - 2.1 8.1 9.4 4.7 6.9 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 GAM23868.1 - 8.5 3.9 6.7 12 3.5 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_2 PF12796.2 GAM23869.1 - 1.5e-16 60.4 7.8 0.0044 17.3 0.0 10.1 4 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM23869.1 - 0.00024 21.0 11.7 34 5.1 0.1 10.4 12 0 0 12 12 12 0 Ankyrin repeat Ank_4 PF13637.1 GAM23869.1 - 0.0032 17.9 11.9 18 6.0 0.4 8.3 10 0 0 10 10 10 1 Ankyrin repeats (many copies) Cwf_Cwc_15 PF04889.7 GAM23869.1 - 0.28 10.8 3.9 0.57 9.8 2.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank PF00023.25 GAM23869.1 - 1.1 9.2 15.3 30 4.6 0.0 8.2 11 0 0 11 11 11 0 Ankyrin repeat Glyoxalase PF00903.20 GAM23870.1 - 3.2e-09 36.8 0.1 2e-07 31.0 0.1 2.8 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM23870.1 - 5.1e-06 27.0 0.0 0.23 12.0 0.0 3.1 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAM23870.1 - 3.9e-05 23.6 0.0 0.31 11.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 GAM23870.1 - 0.021 14.7 0.2 0.15 11.9 0.0 2.4 3 0 0 3 3 3 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 GAM23870.1 - 0.056 13.3 0.0 3.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Glyoxalase-like domain BcrAD_BadFG PF01869.15 GAM23872.1 - 8.8e-40 136.7 0.1 1e-39 136.5 0.1 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Myb_DNA-binding PF00249.26 GAM23873.1 - 0.00033 20.6 0.3 0.00077 19.4 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM23873.1 - 0.0015 18.6 0.2 0.0066 16.5 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF260 PF03195.9 GAM23873.1 - 3 8.1 10.0 0.44 10.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF260 Myb_DNA-binding PF00249.26 GAM23874.1 - 7.8e-08 32.2 0.0 9.8e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain LPP PF04728.8 GAM23874.1 - 0.043 13.6 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ASXH PF13919.1 GAM23875.1 - 0.001 18.8 0.1 0.0073 16.1 0.1 2.2 1 1 0 1 1 1 1 Asx homology domain TATR PF03430.8 GAM23875.1 - 0.33 9.5 8.0 0.53 8.8 5.5 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator NAD_binding_10 PF13460.1 GAM23876.1 - 9.9e-16 58.2 0.1 5.3e-15 55.9 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 GAM23876.1 - 5.6e-11 42.1 0.1 1.6e-09 37.3 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM23876.1 - 0.00027 19.7 0.0 0.0005 18.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 GAM23876.1 - 0.00067 19.3 0.0 0.0017 18.0 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM23876.1 - 0.00096 18.6 0.1 0.0027 17.1 0.1 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 GAM23876.1 - 0.0011 18.9 0.1 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 GAM23876.1 - 0.0093 16.0 0.3 0.02 15.0 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Aa_trans PF01490.13 GAM23877.1 - 3.8e-12 45.4 32.6 7.4e-12 44.4 22.6 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 GAM23877.1 - 6.9e-08 31.7 17.5 6.9e-08 31.7 12.2 2.4 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family DUF3072 PF11272.3 GAM23877.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Lysis_S PF04971.7 GAM23877.1 - 0.1 12.2 0.3 6.9 6.4 0.1 2.9 2 0 0 2 2 2 0 Lysis protein S DUF3007 PF11460.3 GAM23877.1 - 2.3 8.3 8.9 1.4 9.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) Dicty_spore_N PF04562.7 GAM23878.1 - 4.9e-36 123.5 52.0 5.9e-23 81.3 15.4 4.3 4 0 0 4 4 4 2 Dictyostelium spore coat protein, N terminus Pho88 PF10032.4 GAM23879.1 - 1.9e-35 121.8 0.6 3e-35 121.1 0.0 1.5 1 1 1 2 2 2 1 Phosphate transport (Pho88) FLO_LFY PF01698.11 GAM23879.1 - 6.4 5.5 8.5 9.9 4.8 5.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PCI PF01399.22 GAM23880.1 - 1.4e-18 67.1 0.8 2.5e-17 63.0 0.1 3.0 3 0 0 3 3 3 1 PCI domain FadR_C PF07840.7 GAM23880.1 - 0.043 13.4 0.4 0.1 12.2 0.2 1.8 1 1 0 1 1 1 0 FadR C-terminal domain TPR_19 PF14559.1 GAM23880.1 - 0.078 13.3 4.0 0.32 11.3 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Cation_efflux PF01545.16 GAM23881.1 - 0.096 11.7 6.9 0.12 11.4 4.2 1.6 1 1 0 1 1 1 0 Cation efflux family DUF441 PF04284.8 GAM23881.1 - 9.4 6.1 9.7 12 5.8 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF441) RasGEF PF00617.14 GAM23882.1 - 5.7e-58 195.7 0.6 1.7e-56 190.9 0.0 2.5 2 0 0 2 2 2 1 RasGEF domain LRR_4 PF12799.2 GAM23882.1 - 7.8e-43 143.4 40.6 5.4e-09 35.4 0.4 9.0 3 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM23882.1 - 4.4e-35 119.2 36.2 2.1e-10 40.1 0.9 6.5 2 1 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 GAM23882.1 - 6.7e-23 77.2 32.0 0.051 13.6 0.3 14.2 14 0 0 14 14 14 7 Leucine Rich Repeat RasGEF_N PF00618.15 GAM23882.1 - 8.7e-23 80.4 0.6 8.7e-23 80.4 0.4 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif LRR_7 PF13504.1 GAM23882.1 - 1.2e-11 42.7 35.2 0.82 10.1 0.8 12.9 13 0 0 13 13 13 4 Leucine rich repeat LRR_6 PF13516.1 GAM23882.1 - 3.8e-05 23.3 30.4 2.3 8.5 0.2 10.8 11 1 0 11 11 11 2 Leucine Rich repeat LRR_5 PF13306.1 GAM23882.1 - 0.012 15.3 2.6 0.59 9.8 0.1 3.0 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) IQ PF00612.22 GAM23882.1 - 0.03 13.9 15.6 0.2 11.3 4.1 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Oxysterol_BP PF01237.13 GAM23883.1 - 1.8e-105 352.3 1.0 2.2e-105 352.0 0.7 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2075 PF09848.4 GAM23883.1 - 0.0074 15.3 1.0 0.011 14.6 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Epimerase PF01370.16 GAM23884.1 - 3.1e-66 223.2 0.0 4.2e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM23884.1 - 0.00017 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 GAM23884.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit NmrA PF05368.8 GAM23884.1 - 0.032 13.5 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 GAM23884.1 - 0.15 12.0 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding NUC194 PF08163.7 GAM23885.1 - 3.1e-72 243.6 4.4 2.5e-54 184.6 2.3 2.6 2 0 0 2 2 2 2 NUC194 domain PI3_PI4_kinase PF00454.22 GAM23885.1 - 5e-45 153.8 0.1 2e-44 151.8 0.1 2.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 GAM23885.1 - 7.3e-17 61.3 3.8 7.3e-17 61.3 2.6 2.2 2 0 0 2 2 2 1 FAT domain FATC PF02260.15 GAM23885.1 - 5.7e-10 38.4 0.6 1.5e-09 37.1 0.4 1.8 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 GAM23885.1 - 0.36 10.8 3.0 7.6 6.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2457 PF10446.4 GAM23885.1 - 5.8 5.5 17.2 15 4.1 11.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Endotoxin_C PF03944.9 GAM23886.1 - 0.06 13.4 0.0 0.08 13.0 0.0 1.1 1 0 0 1 1 1 0 delta endotoxin Endotoxin_N PF03945.9 GAM23887.1 - 8.6e-28 97.2 5.1 1.3e-27 96.6 3.5 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain EAV_GS PF01309.13 GAM23888.1 - 0.074 12.5 0.1 0.087 12.3 0.0 1.0 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Endotoxin_N PF03945.9 GAM23889.1 - 5.4e-28 97.9 3.1 9.5e-28 97.1 2.1 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain DUF2765 PF10963.3 GAM23889.1 - 0.029 14.3 0.1 0.071 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) DIL PF01843.14 GAM23890.1 - 2.8e-25 88.2 0.1 7.8e-25 86.7 0.1 1.8 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 GAM23890.1 - 1.7e-07 30.2 3.7 0.00018 20.8 0.2 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif Cep57_CLD_2 PF14197.1 GAM23890.1 - 0.017 15.0 3.7 0.017 15.0 2.6 2.3 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 AAA_27 PF13514.1 GAM23890.1 - 0.019 12.6 2.4 0.027 12.1 1.7 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 GAM23890.1 - 0.17 11.4 6.1 0.31 10.6 4.2 1.4 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 GAM23890.1 - 0.18 11.0 7.4 0.34 10.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4201 PF13870.1 GAM23890.1 - 0.66 9.3 12.5 1.3 8.4 2.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Methyltransf_11 PF08241.7 GAM23891.1 - 1.1e-18 67.5 0.0 1.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM23891.1 - 3.5e-15 56.0 0.0 5.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23891.1 - 6.6e-15 55.0 0.0 8.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23891.1 - 2.4e-14 53.8 0.0 3.3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23891.1 - 4.4e-14 52.7 0.0 7.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23891.1 - 1e-12 48.2 0.1 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23891.1 - 1.7e-09 37.1 0.0 2.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAM23891.1 - 5.4e-07 29.6 0.0 8.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAM23891.1 - 8.1e-05 21.8 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 GAM23891.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Aminotran_3 PF00202.16 GAM23892.1 - 8.5e-78 261.5 0.0 1.1e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 GAM23892.1 - 4.6e-05 22.5 0.0 0.0007 18.6 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM23892.1 - 0.048 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_S10 PF00450.17 GAM23893.1 - 5e-119 398.1 1.0 5.8e-119 397.9 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase_Tyr PF07714.12 GAM23894.1 - 7.3e-55 185.8 0.0 1.1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23894.1 - 1.2e-51 175.4 0.0 2.1e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kelch_6 PF13964.1 GAM23895.1 - 3.2e-36 122.0 7.1 3.5e-07 30.1 0.1 6.9 3 2 4 7 7 7 5 Kelch motif Kelch_4 PF13418.1 GAM23895.1 - 2.5e-35 119.9 5.3 2.5e-06 27.1 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM23895.1 - 1.3e-33 114.4 3.7 4.2e-06 26.7 0.0 7.4 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM23895.1 - 1.7e-32 110.6 6.2 5.1e-09 35.5 0.0 6.9 6 2 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 GAM23895.1 - 1.7e-28 98.0 8.2 2.6e-06 27.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM23895.1 - 1e-21 75.7 7.1 5.3e-05 22.8 0.0 6.5 7 1 0 7 7 7 4 Kelch motif F-box-like PF12937.2 GAM23895.1 - 3.1e-08 33.1 0.0 6.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM23895.1 - 6.4e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain V-SNARE_C PF12352.3 GAM23896.1 - 1.5e-05 24.9 4.1 3.1e-05 23.9 2.8 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus IATP PF04568.7 GAM23896.1 - 0.28 11.2 1.1 0.65 10.0 0.8 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Topoisom_I_N PF02919.10 GAM23898.1 - 4e-89 297.5 2.3 4e-89 297.5 1.6 3.0 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 GAM23898.1 - 1.1e-85 286.4 2.8 1.1e-85 286.4 2.0 2.5 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 GAM23898.1 - 1.3e-30 104.8 0.2 4.1e-30 103.2 0.1 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain Methyltransf_23 PF13489.1 GAM23899.1 - 4.9e-18 65.3 0.0 1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23899.1 - 2.5e-17 63.1 0.0 1.8e-16 60.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23899.1 - 3.1e-15 56.0 0.0 9.8e-15 54.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23899.1 - 1.1e-12 48.5 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM23899.1 - 1.8e-12 47.5 0.0 4.4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23899.1 - 4.4e-09 36.6 0.0 1.4e-08 35.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23899.1 - 1.2e-07 31.1 0.0 3.7e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 GAM23899.1 - 8.9e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 GAM23899.1 - 3.4e-05 23.1 0.5 0.00013 21.2 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_8 PF05148.10 GAM23899.1 - 4.6e-05 23.1 0.1 0.00029 20.5 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 GAM23899.1 - 0.00019 20.5 0.0 0.0051 15.8 0.0 2.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 GAM23899.1 - 0.00039 19.8 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 GAM23899.1 - 0.0097 15.4 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) FmrO PF07091.6 GAM23899.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_24 PF13578.1 GAM23899.1 - 0.08 13.7 0.0 0.21 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 GAM23899.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Auxin_repressed PF05564.7 GAM23899.1 - 3.9 8.1 7.9 3.1 8.4 1.3 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein LMBR1 PF04791.11 GAM23900.1 - 1.8e-38 132.3 32.0 4.5e-27 94.7 5.7 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein IMPDH PF00478.20 GAM23901.1 - 5.8e-133 443.1 3.3 7.1e-133 442.8 2.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 GAM23901.1 - 5.4e-15 54.9 0.1 9.9e-09 34.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 GAM23901.1 - 1.2e-11 44.4 1.4 1.2e-07 31.2 0.5 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 GAM23901.1 - 1.9e-06 26.9 0.7 9.7e-06 24.6 0.8 1.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.9 GAM23901.1 - 0.00038 19.6 0.1 0.00082 18.5 0.1 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 GAM23901.1 - 0.00051 19.3 1.5 0.0013 18.0 0.2 1.9 1 1 0 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 GAM23901.1 - 0.034 13.0 0.4 0.094 11.6 0.2 1.7 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase GST_N PF02798.15 GAM23903.1 - 4.8e-12 45.8 0.0 9.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM23903.1 - 6.2e-09 35.7 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM23903.1 - 5.3e-07 30.0 0.0 7.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM23903.1 - 3.6e-05 23.5 0.1 7.3e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM23903.1 - 0.00051 20.2 0.0 0.00092 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Cortex-I_coil PF09304.5 GAM23904.1 - 3.7e-33 113.7 22.8 3.7e-33 113.7 15.8 3.1 2 1 1 3 3 3 1 Cortexillin I, coiled coil CH PF00307.26 GAM23904.1 - 9e-19 67.5 0.1 4.2e-16 58.9 0.0 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM23904.1 - 0.037 13.6 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 CAMSAP CH domain CENP-F_leu_zip PF10473.4 GAM23904.1 - 0.64 9.8 35.4 0.032 14.0 7.6 3.2 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RBD-FIP PF09457.5 GAM23904.1 - 2.2 8.1 12.1 0.1 12.4 2.1 3.3 3 0 0 3 3 3 0 FIP domain Band_7 PF01145.20 GAM23904.1 - 3.9 7.3 6.1 8.5 6.2 4.2 1.6 1 0 0 1 1 1 0 SPFH domain / Band 7 family CCDC155 PF14662.1 GAM23904.1 - 5.1 6.6 30.2 0.72 9.4 17.3 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 FUSC PF04632.7 GAM23904.1 - 5.4 5.3 11.9 7.3 4.8 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.7 GAM23904.1 - 6.3 6.6 9.7 0.57 9.9 2.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.14 GAM23904.1 - 8.5 5.8 31.5 0.53 9.7 7.1 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CH PF00307.26 GAM23905.1 - 1.9e-12 47.1 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Rifin_STEVOR PF02009.11 GAM23906.1 - 0.43 10.1 2.6 0.72 9.4 1.8 1.4 1 0 0 1 1 1 0 Rifin/stevor family FNIP PF05725.7 GAM23907.1 - 1.7e-58 194.2 25.2 4.8e-14 52.0 0.1 6.8 6 2 1 7 7 7 6 FNIP Repeat LRR_8 PF13855.1 GAM23907.1 - 3.7e-06 26.6 0.6 0.005 16.5 0.0 3.8 3 1 2 5 5 5 2 Leucine rich repeat Crystallin PF00525.13 GAM23907.1 - 0.015 15.4 2.3 0.15 12.3 0.2 3.3 2 1 2 4 4 4 0 Alpha crystallin A chain, N terminal LRR_4 PF12799.2 GAM23907.1 - 0.096 12.3 3.3 0.21 11.2 0.1 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Ras PF00071.17 GAM23908.1 - 1.9e-56 189.9 0.0 2.2e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM23908.1 - 2.5e-14 53.7 0.0 5e-14 52.8 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM23908.1 - 2.9e-09 36.3 0.0 3.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM23908.1 - 0.00043 19.7 0.0 0.0006 19.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM23908.1 - 0.0052 16.7 0.0 0.0066 16.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM23908.1 - 0.05 12.7 0.0 0.064 12.3 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAM23908.1 - 0.079 13.0 0.1 0.47 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 GAM23908.1 - 0.093 12.1 0.1 0.65 9.3 0.0 2.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF258 PF03193.11 GAM23908.1 - 0.1 11.7 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 LcrG PF07216.7 GAM23908.1 - 0.15 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 LcrG protein eIF2A PF08662.6 GAM23909.1 - 1.2e-56 191.5 7.7 1.2e-52 178.4 0.5 4.2 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 GAM23909.1 - 8.2e-06 25.3 0.2 8.2e-06 25.3 0.1 2.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM23909.1 - 0.006 16.5 0.1 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 GAM23909.1 - 0.0064 16.3 0.8 13 5.8 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat RRM_5 PF13893.1 GAM23909.1 - 0.031 14.1 0.2 0.11 12.3 0.2 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GvpG PF05120.7 GAM23909.1 - 1.6 8.5 6.0 2.3 8.1 0.4 3.4 4 0 0 4 4 4 0 Gas vesicle protein G Glyco_transf_10 PF00852.14 GAM23910.1 - 8.7e-49 165.9 0.4 1.4e-48 165.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Laminin_G_3 PF13385.1 GAM23910.1 - 6.7e-18 65.4 0.4 1.6e-17 64.2 0.1 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2418 PF10332.4 GAM23911.1 - 7.4e-13 48.6 1.0 2.1e-12 47.1 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2418) 7tm_2 PF00002.19 GAM23912.1 - 2e-07 30.3 14.2 2.3e-07 30.1 9.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 GAM23912.1 - 5.3e-05 22.2 15.2 7e-05 21.8 10.5 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor LSM PF01423.17 GAM23913.1 - 3.7e-17 61.6 0.0 4.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM23913.1 - 0.048 13.5 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain FNIP PF05725.7 GAM23914.1 - 1.9e-51 171.7 36.8 1.4e-12 47.3 0.9 8.1 4 2 3 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM23914.1 - 0.00035 20.4 2.1 1.3 9.0 0.0 4.6 3 2 1 4 4 4 2 Protein of unknown function (DUF1769) DUF393 PF04134.7 GAM23915.1 - 1.8e-20 74.1 0.0 2.4e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Melibiase PF02065.13 GAM23916.1 - 1.3e-16 60.2 0.1 5.2e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 GAM23916.1 - 0.0021 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 MDM31_MDM32 PF08118.6 GAM23918.1 - 4.3e-72 243.1 1.8 2.4e-47 161.5 0.0 3.0 1 1 1 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins DXP_redisom_C PF08436.7 GAM23919.1 - 0.088 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal DUF1628 PF07790.6 GAM23919.1 - 0.13 12.9 0.4 9 7.1 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1628) Serglycin PF04360.7 GAM23919.1 - 0.34 10.6 2.9 0.75 9.5 2.0 1.6 1 0 0 1 1 1 0 Serglycin GPCR_chapero_1 PF11904.3 GAM23920.1 - 6e-52 176.6 0.8 2.4e-51 174.7 0.6 1.8 1 1 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 GAM23920.1 - 1.1e-13 51.3 0.1 3.5e-07 30.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM23920.1 - 5.9e-05 23.1 0.3 0.00018 21.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM23920.1 - 0.0002 21.7 0.1 0.00045 20.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM23920.1 - 0.0004 20.3 0.5 0.023 14.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 GAM23920.1 - 0.00086 19.0 0.2 0.0059 16.3 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat TSA PF03249.8 GAM23920.1 - 0.18 10.3 0.1 0.25 9.8 0.1 1.1 1 0 0 1 1 1 0 Type specific antigen DJ-1_PfpI PF01965.19 GAM23922.1 - 1.6e-30 105.5 0.0 1.8e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 GAM23922.1 - 1.9e-12 46.7 0.0 2.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 GAM23922.1 - 0.0003 20.2 0.0 0.00061 19.2 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 GAM23922.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 GAM23922.1 - 0.047 13.3 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 GAM23922.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 Peptidase C26 EMP70 PF02990.11 GAM23924.1 - 2e-92 310.3 14.6 2.9e-92 309.8 10.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 2OG-FeII_Oxy_3 PF13640.1 GAM23925.1 - 6e-06 26.6 0.0 9.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM23925.1 - 1.6e-05 25.1 0.0 2.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAPRTase PF04095.11 GAM23925.1 - 0.015 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Adaptin_N PF01602.15 GAM23927.1 - 1.6e-65 221.4 9.7 3.2e-65 220.4 6.7 1.5 1 0 0 1 1 1 1 Adaptin N terminal region AP4E_app_platf PF14807.1 GAM23927.1 - 3e-17 62.7 0.0 1e-16 61.0 0.0 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Cnd1 PF12717.2 GAM23927.1 - 2.6e-06 27.3 0.7 0.0023 17.8 0.0 3.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAM23927.1 - 0.00013 22.1 0.3 0.1 12.8 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats UME PF08064.8 GAM23927.1 - 0.00041 20.2 1.6 0.068 13.1 0.1 3.1 2 0 0 2 2 2 2 UME (NUC010) domain HEAT PF02985.17 GAM23927.1 - 0.49 10.6 4.6 22 5.4 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat Virul_fac_BrkB PF03631.10 GAM23928.1 - 7.3e-06 25.5 0.1 7.3e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 Virulence factor BrkB 7tm_1 PF00001.16 GAM23928.1 - 3e-05 23.3 8.2 8.1e-05 21.8 2.7 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 GAM23928.1 - 7.6e-05 22.3 1.7 7.6e-05 22.3 1.2 2.7 3 1 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term PepSY_TM_2 PF13703.1 GAM23928.1 - 0.0019 18.3 0.3 0.0019 18.3 0.2 2.3 2 2 0 2 2 2 1 PepSY-associated TM helix Orbi_NS3 PF01616.11 GAM23928.1 - 0.0026 16.7 1.0 0.006 15.5 0.2 1.8 2 0 0 2 2 2 1 Orbivirus NS3 UPF0014 PF03649.8 GAM23928.1 - 0.093 11.8 3.9 0.036 13.2 0.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) DUF805 PF05656.9 GAM23928.1 - 0.38 10.5 3.1 0.5 10.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF996 PF06195.8 GAM23928.1 - 0.39 10.7 8.1 0.079 12.9 1.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF996) EI24 PF07264.6 GAM23928.1 - 7.6 5.8 10.3 97 2.2 7.2 2.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Cofilin_ADF PF00241.15 GAM23929.1 - 0.015 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein ETC_C1_NDUFA5 PF04716.9 GAM23930.1 - 4.4e-15 54.9 0.5 7.4e-15 54.2 0.4 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pox_mRNA-cap PF03341.8 GAM23930.1 - 0.0099 14.9 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 1 Poxvirus mRNA capping enzyme, small subunit BcrAD_BadFG PF01869.15 GAM23930.1 - 0.077 12.2 0.1 0.091 12.0 0.1 1.1 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Complex1_LYR_1 PF13232.1 GAM23930.1 - 0.23 11.7 1.2 0.45 10.7 0.8 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.10 GAM23930.1 - 0.25 11.1 1.8 0.49 10.2 1.2 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) HECT PF00632.20 GAM23931.1 - 1.6e-72 244.3 0.9 3.1e-72 243.3 0.7 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.14 GAM23931.1 - 9.8e-18 64.5 0.4 1.3e-10 41.7 0.1 3.0 3 0 0 3 3 3 2 Filamin/ABP280 repeat Neurexophilin PF06312.7 GAM23931.1 - 0.0049 16.1 1.3 0.0076 15.5 0.3 1.7 2 0 0 2 2 2 1 Neurexophilin CASP_C PF08172.7 GAM23932.1 - 1.7e-60 204.0 4.1 1.7e-60 204.0 2.9 5.6 2 1 3 5 5 5 1 CASP C terminal CENP-F_leu_zip PF10473.4 GAM23932.1 - 0.00031 20.6 6.5 0.00031 20.6 4.5 5.7 4 2 1 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 GAM23932.1 - 0.0039 16.7 21.2 0.0039 16.7 14.7 5.3 4 1 1 5 5 5 3 IncA protein FlaC_arch PF05377.6 GAM23932.1 - 0.036 13.9 0.7 0.033 14.0 1.4 7.6 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) GAS PF13851.1 GAM23932.1 - 1.9 7.6 68.8 1.9 7.6 13.4 6.3 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 GAM23932.1 - 2.5 7.5 65.8 1.7 8.0 27.4 5.6 2 1 2 4 4 4 0 Intermediate filament protein MFS_1 PF07690.11 GAM23933.1 - 4.8e-20 71.5 40.4 4.6e-12 45.3 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 GAM23933.1 - 2.4e-15 56.3 13.5 2.4e-15 56.3 9.3 3.2 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 GAM23933.1 - 0.65 8.5 25.5 1.4 7.3 5.0 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter Ubie_methyltran PF01209.13 GAM23934.1 - 1.7e-16 60.0 0.0 4.7e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAM23934.1 - 1e-15 57.9 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23934.1 - 1.4e-11 44.2 0.0 2.8e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23934.1 - 1.8e-10 41.3 0.0 3.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23934.1 - 7.9e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM23934.1 - 2.4e-09 37.1 0.0 4.7e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23934.1 - 7e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 GAM23934.1 - 0.0018 17.2 0.0 0.0037 16.1 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 GAM23934.1 - 0.004 16.5 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 GAM23934.1 - 0.0064 16.0 0.0 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 GAM23934.1 - 0.0089 15.0 0.0 0.018 14.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 GAM23934.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 GAM23934.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 GAM23935.1 - 3.8e-17 62.5 0.0 5.8e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23935.1 - 4.8e-16 58.5 0.0 3.3e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAM23935.1 - 4.1e-12 45.9 0.0 8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23935.1 - 4.8e-09 36.5 0.0 8.4e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23935.1 - 2.1e-08 34.7 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM23935.1 - 2.2e-08 33.9 0.0 4.5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23935.1 - 3.8e-05 23.9 0.0 7.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM23935.1 - 0.0051 15.9 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 GAM23935.1 - 0.029 13.2 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 GAM23935.1 - 0.037 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 GAM23935.1 - 0.042 12.8 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAM23935.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 GAM23935.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 GAM23936.1 - 4.1e-18 65.6 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM23936.1 - 5e-14 52.1 0.0 9.7e-14 51.2 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM23936.1 - 4.7e-13 48.8 0.0 6.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAM23936.1 - 4.6e-10 39.4 0.0 6.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM23936.1 - 1.3e-09 38.3 0.0 2.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM23936.1 - 4.3e-09 36.9 0.0 7.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM23936.1 - 7e-06 26.3 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAM23936.1 - 0.00013 21.1 0.0 0.00025 20.2 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.7 GAM23936.1 - 0.0014 17.5 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_26 PF13659.1 GAM23936.1 - 0.0047 16.9 0.0 0.027 14.4 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 GAM23936.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 GAM23936.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 GAM23936.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 GAM23936.1 - 0.056 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF179 PF02622.10 GAM23938.1 - 3.1e-26 91.9 0.0 4.3e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 dsrm PF00035.20 GAM23939.1 - 0.00087 19.8 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif eRF1_2 PF03464.10 GAM23940.1 - 1.2e-43 148.5 0.0 2e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAM23940.1 - 1.1e-35 122.3 0.0 2.5e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 GAM23940.1 - 5.5e-28 97.1 0.0 9.9e-28 96.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 GST_N PF02798.15 GAM23941.1 - 4e-13 49.3 0.0 7.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM23941.1 - 6.8e-10 38.8 0.0 9.9e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM23941.1 - 4.2e-07 30.0 0.1 1.3e-06 28.4 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM23941.1 - 7.1e-07 29.6 0.0 1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM23941.1 - 0.013 15.4 0.1 0.025 14.4 0.1 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM23941.1 - 0.045 13.7 0.3 0.14 12.1 0.0 2.0 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain E1-E2_ATPase PF00122.15 GAM23942.1 - 3.2e-58 196.4 5.4 3.2e-58 196.4 3.7 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM23942.1 - 8.3e-41 139.5 3.3 8.3e-41 139.5 2.3 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM23942.1 - 8.1e-32 111.3 0.0 3.6e-31 109.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM23942.1 - 2.7e-16 58.7 0.0 8.1e-16 57.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 GAM23942.1 - 3.9e-14 53.2 0.0 8.7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM23942.1 - 5.5e-07 29.4 0.2 0.014 15.3 0.0 3.1 2 1 1 3 3 3 2 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM23942.1 - 4.6e-06 26.3 1.5 0.0017 18.0 0.2 3.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase MerC PF03203.9 GAM23942.1 - 0.48 10.8 5.8 0.1 12.9 0.5 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein DUF3040 PF11239.3 GAM23942.1 - 0.8 9.7 6.9 0.22 11.5 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Mito_carr PF00153.22 GAM23943.1 - 1.6e-63 210.4 2.3 7.1e-21 73.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 GAM23943.1 - 0.051 13.6 1.3 0.74 9.8 0.1 2.7 2 2 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family NYAP_C PF15452.1 GAM23943.1 - 0.088 11.8 0.3 7.4 5.4 0.0 2.6 3 0 0 3 3 3 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Pkinase_Tyr PF07714.12 GAM23944.1 - 3e-61 206.7 0.0 6.2e-61 205.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23944.1 - 2.9e-49 167.5 0.0 5.9e-49 166.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain FNIP PF05725.7 GAM23945.1 - 6.7e-61 202.0 27.9 8.9e-15 54.3 0.1 9.4 4 2 4 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM23945.1 - 8.5e-07 28.8 4.0 2.3 8.2 0.0 6.5 4 2 1 6 6 6 3 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM23946.1 - 1.3e-50 169.0 39.8 1.3e-14 53.8 0.6 9.8 7 3 3 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 GAM23946.1 - 1.6e-05 24.7 4.2 0.4 10.6 0.0 5.8 3 1 3 6 6 6 3 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM23947.1 - 4e-05 23.4 1.8 0.0075 16.1 0.4 3.0 1 1 1 2 2 2 2 FNIP Repeat Tyrosinase PF00264.15 GAM23948.1 - 1.4e-34 120.2 4.6 1.9e-34 119.7 3.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Complex1_LYR PF05347.10 GAM23950.1 - 1.4e-13 50.3 1.1 1.9e-13 49.9 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM23950.1 - 9e-12 45.0 1.4 1.2e-11 44.6 1.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 GAM23950.1 - 0.033 14.6 0.4 0.044 14.2 0.3 1.1 1 0 0 1 1 1 0 Complex1_LYR-like DUF2856 PF11043.3 GAM23950.1 - 0.12 12.5 0.9 0.15 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) GalP_UDP_tr_C PF02744.12 GAM23951.1 - 0.0012 18.3 0.0 0.0044 16.5 0.0 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 GAM23951.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain p450 PF00067.17 GAM23952.1 - 1.1e-101 340.7 0.0 1.3e-101 340.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FhuF PF06276.7 GAM23952.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter DUF3522 PF12036.3 GAM23954.1 - 2.9e-43 147.8 8.6 3.7e-43 147.4 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) HlyIII PF03006.15 GAM23954.1 - 0.00075 18.9 11.2 0.0013 18.1 7.7 1.4 1 0 0 1 1 1 1 Haemolysin-III related DUF2955 PF11168.3 GAM23954.1 - 0.37 10.4 5.7 0.6 9.7 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2955) DUF2404 PF10296.4 GAM23955.1 - 4.9e-25 87.4 0.8 8.3e-25 86.7 0.1 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 GAM23955.1 - 0.014 15.5 0.2 0.037 14.2 0.1 1.7 1 0 0 1 1 1 0 PH domain Tropomodulin PF03250.9 GAM23955.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Tropomodulin DUF3465 PF11948.3 GAM23955.1 - 0.053 13.3 0.1 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) UBA PF00627.26 GAM23956.1 - 2.6e-10 39.8 0.2 5.7e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.17 GAM23956.1 - 0.001 19.1 8.8 0.0014 18.7 6.1 1.1 1 0 0 1 1 1 1 Rhomboid family E3_UbLigase_EDD PF11547.3 GAM23956.1 - 0.031 13.7 0.1 0.069 12.6 0.1 1.6 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD UBA_3 PF09288.5 GAM23956.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Actin PF00022.14 GAM23957.1 - 3.7e-33 114.5 0.0 1.6e-26 92.6 0.0 2.5 2 1 0 2 2 2 2 Actin SecE PF00584.15 GAM23958.1 - 6.8e-15 54.3 0.1 7.7e-15 54.2 0.1 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF2976 PF11190.3 GAM23958.1 - 0.065 12.7 0.0 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF663 PF04950.7 GAM23959.1 - 1.9e-80 270.0 0.1 1.9e-80 270.0 0.1 3.0 3 0 0 3 3 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 GAM23959.1 - 5.5e-29 99.5 0.0 1.9e-28 97.8 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 GAM23959.1 - 1.3e-07 31.2 1.3 2e-05 24.0 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM23959.1 - 5.6e-06 26.2 0.1 2.3e-05 24.3 0.1 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM23959.1 - 0.00023 21.0 0.0 0.0014 18.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM23959.1 - 0.00096 19.9 0.0 0.00096 19.9 0.0 4.6 5 2 0 5 5 3 1 AAA domain MobB PF03205.9 GAM23959.1 - 0.0011 18.6 0.1 0.0057 16.3 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 GAM23959.1 - 0.0019 17.6 0.0 0.0056 16.1 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 GAM23959.1 - 0.0038 17.4 0.0 0.016 15.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM23959.1 - 0.0038 17.3 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAM23959.1 - 0.0077 16.7 1.0 0.023 15.1 0.0 2.4 2 0 0 2 2 1 1 Miro-like protein AAA_33 PF13671.1 GAM23959.1 - 0.0097 15.7 0.9 0.023 14.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 GAM23959.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 GAM23959.1 - 0.034 13.4 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 GAM23959.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Pkinase_Tyr PF07714.12 GAM23960.1 - 5.1e-50 169.9 0.0 8.4e-50 169.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM23960.1 - 7.5e-47 159.6 0.0 1.2e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAM23960.1 - 9.6e-34 115.5 3.4 5.1e-13 49.1 0.4 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM23960.1 - 4.8e-29 100.1 4.6 1.1e-06 29.0 0.0 6.5 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM23960.1 - 6.3e-28 95.1 0.8 3.7e-06 26.4 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 GAM23960.1 - 6.7e-22 75.3 2.4 0.00013 21.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAM23960.1 - 1.4e-21 76.0 1.6 1.6e-07 31.3 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SAM_1 PF00536.25 GAM23960.1 - 3.5e-12 46.3 0.2 1.2e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM23960.1 - 2.5e-10 40.0 0.1 5.5e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Radical_SAM_N PF08497.5 GAM23960.1 - 0.051 12.5 0.2 0.098 11.5 0.1 1.4 1 0 0 1 1 1 0 Radical SAM N-terminal APH PF01636.18 GAM23960.1 - 0.073 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.7 GAM23961.1 - 1.5e-57 191.2 16.3 1e-13 50.9 0.1 8.3 5 2 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM23961.1 - 0.001 18.9 2.0 2.9 7.8 0.0 4.3 4 1 1 5 5 5 2 Protein of unknown function (DUF1769) ATP-synt_10 PF05176.9 GAM23963.1 - 4.3e-16 58.9 0.0 5.3e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein UbiA PF01040.13 GAM23964.1 - 3.4e-30 105.1 13.7 4.9e-30 104.6 9.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-DHHC PF01529.15 GAM23964.1 - 8.4 5.7 6.5 1.2 8.5 0.1 2.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase CTP_transf_2 PF01467.21 GAM23965.1 - 3.8e-22 79.0 0.1 8.3e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Cytidylyltransferase Pex14_N PF04695.8 GAM23965.1 - 0.43 10.6 6.0 0.17 11.9 0.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 GAM23966.1 - 1.7e-13 49.8 8.9 1.7e-08 33.9 0.1 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 GAM23966.1 - 0.041 14.1 0.0 0.22 11.8 0.0 2.3 1 0 0 1 1 1 0 PQQ-like domain Ebp2 PF05890.7 GAM23967.1 - 5.6e-73 245.5 39.7 5.6e-73 245.5 27.5 2.9 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF2756 PF10956.3 GAM23970.1 - 1.2 9.3 7.8 0.43 10.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) Endonuclease_NS PF01223.18 GAM23971.1 - 7.1e-34 117.2 1.0 1.4e-18 67.2 1.3 2.3 1 1 1 2 2 2 2 DNA/RNA non-specific endonuclease Orbi_VP5 PF00901.12 GAM23971.1 - 0.033 12.4 0.9 0.048 11.8 0.6 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 PIP5K PF01504.13 GAM23972.1 - 3e-83 278.7 0.1 5.5e-83 277.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase V-SNARE_C PF12352.3 GAM23973.1 - 2.2e-15 56.4 3.7 2.9e-15 56.0 1.6 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAM23973.1 - 6e-07 29.0 0.4 6e-07 29.0 0.3 2.5 2 1 0 3 3 3 1 Sec20 SPX PF03105.14 GAM23973.1 - 0.0018 18.0 2.3 0.0055 16.5 1.6 1.6 1 1 0 1 1 1 1 SPX domain DUF4208 PF13907.1 GAM23973.1 - 0.025 14.7 1.7 0.048 13.8 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) Phage_hub_GP28 PF11110.3 GAM23973.1 - 0.039 13.6 0.7 0.75 9.4 0.1 2.2 2 0 0 2 2 2 0 Baseplate hub distal subunit Zot PF05707.7 GAM23973.1 - 0.053 12.9 0.3 0.089 12.2 0.2 1.6 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) NPV_P10 PF05531.7 GAM23973.1 - 0.074 13.3 5.9 8.2 6.7 0.4 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1759 PF03564.10 GAM23973.1 - 0.33 10.7 6.8 0.13 12.0 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) DUF948 PF06103.6 GAM23973.1 - 0.42 10.4 6.7 3.8 7.4 0.1 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 GAM23973.1 - 0.63 8.3 11.7 0.1 10.9 5.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Sporozoite_P67 PF05642.6 GAM23973.1 - 3.9 5.2 8.7 5.9 4.6 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1900 PF08954.6 GAM23974.1 - 3.5e-88 292.1 0.1 3.9e-47 159.1 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF1900) WD40 PF00400.27 GAM23974.1 - 1.7e-37 125.9 14.7 1.1e-08 34.6 0.0 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat DUF1899 PF08953.6 GAM23974.1 - 7.9e-32 108.7 3.7 2.9e-16 58.8 0.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) IKI3 PF04762.7 GAM23974.1 - 0.0096 13.7 1.6 0.064 11.0 0.0 2.4 2 1 1 3 3 3 1 IKI3 family DUF1652 PF07865.6 GAM23974.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) PH PF00169.24 GAM23975.1 - 3.3e-14 52.9 0.6 4.8e-14 52.4 0.4 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM23975.1 - 5.3e-10 39.5 0.4 7.1e-10 39.1 0.3 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM23975.1 - 0.00029 20.8 1.6 0.0021 18.0 0.3 2.1 1 1 1 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 GAM23975.1 - 0.00088 19.4 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain Syntaxin-6_N PF09177.6 GAM23975.1 - 0.13 12.6 0.1 0.22 11.9 0.1 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal RhoGAP PF00620.22 GAM23976.1 - 1.5e-25 89.5 0.7 5.5e-25 87.7 0.5 1.9 1 0 0 1 1 1 1 RhoGAP domain Ferrochelatase PF00762.14 GAM23977.1 - 0.00085 18.3 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase GPP34 PF05719.6 GAM23977.1 - 0.03 14.3 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) DUF234 PF03008.9 GAM23977.1 - 0.06 13.4 0.3 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function Nexin_C PF08628.7 GAM23977.1 - 0.14 12.2 0.6 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Sorting nexin C terminal RRM_1 PF00076.17 GAM23978.1 - 1.2e-10 40.8 0.1 2.2e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM23978.1 - 2.7e-08 33.6 0.0 5.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM23978.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 GAM23978.1 - 0.0022 17.6 1.8 0.0022 17.6 1.2 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3445 PF11927.3 GAM23978.1 - 0.0041 16.5 2.5 0.0066 15.8 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1510 PF07423.6 GAM23978.1 - 0.0057 16.0 4.6 0.0087 15.4 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FYVE PF01363.16 GAM23978.1 - 0.022 14.6 0.9 0.022 14.6 0.6 2.1 2 0 0 2 2 2 0 FYVE zinc finger DUF2201_N PF13203.1 GAM23978.1 - 0.041 13.0 4.1 0.06 12.5 2.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RRM_3 PF08777.6 GAM23978.1 - 0.045 13.5 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 RNA binding motif Hid1 PF12722.2 GAM23978.1 - 0.11 10.1 5.3 0.15 9.7 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-CCCH_2 PF14608.1 GAM23978.1 - 7.8 6.6 6.6 2.6 8.1 2.4 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF793 PF05633.6 GAM23979.1 - 2.2 6.9 5.1 0.45 9.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF793) tRNA-synt_1 PF00133.17 GAM23980.1 - 2.5e-181 603.7 0.0 2.3e-180 600.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM23980.1 - 5.7e-27 94.3 0.3 1e-26 93.5 0.2 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM23980.1 - 2e-19 69.5 0.1 3.3e-09 35.9 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAM23980.1 - 5.7e-11 42.0 0.0 1.8e-06 27.4 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAM23980.1 - 2.5e-06 26.8 0.0 0.076 12.1 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 GAM23980.1 - 0.00012 21.0 0.0 0.001 17.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 GAM23980.1 - 0.024 13.7 0.1 0.079 12.0 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) MIT PF04212.13 GAM23981.1 - 9.4e-27 92.6 13.4 2.3e-13 49.8 2.9 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain LIM PF00412.17 GAM23981.1 - 0.0023 17.9 0.3 0.0045 17.0 0.2 1.4 1 0 0 1 1 1 1 LIM domain MPLKIP PF15502.1 GAM23981.1 - 0.016 15.9 9.3 0.016 15.9 6.5 2.4 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein TPR_7 PF13176.1 GAM23981.1 - 0.26 11.1 1.7 1.3 8.9 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TOM20_plant PF06552.7 GAM23981.1 - 0.35 10.4 3.1 0.73 9.3 2.1 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.1 GAM23981.1 - 1.2 8.8 5.6 2.4 7.8 1.3 2.7 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 GAM23981.1 - 3.1 7.9 9.4 1.7 8.7 0.6 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF334 PF03904.8 GAM23982.1 - 0.46 9.7 8.7 0.58 9.4 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Tetraspannin PF00335.15 GAM23982.1 - 0.5 9.5 31.5 0.82 8.9 19.2 2.4 1 1 1 2 2 2 0 Tetraspanin family CbiQ PF02361.11 GAM23982.1 - 2.7 7.5 17.8 3.4 7.1 12.3 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF3488 PF11992.3 GAM23982.1 - 3.4 6.2 6.7 3.9 6.0 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Nop53 PF07767.6 GAM23983.1 - 4.7e-29 101.5 40.4 1.3e-28 100.1 28.0 1.6 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1509 PF07420.6 GAM23983.1 - 0.078 12.2 0.8 0.13 11.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) REV PF00424.13 GAM23983.1 - 4.6 7.1 10.4 2.5 8.0 3.2 2.7 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) FA_desaturase PF00487.19 GAM23984.1 - 9.3e-18 64.5 20.8 7.4e-16 58.3 14.4 2.3 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 GAM23984.1 - 2.5e-08 34.0 0.0 4.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) LRR_6 PF13516.1 GAM23985.1 - 1.3e-05 24.7 21.3 0.0066 16.3 0.0 7.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.2 GAM23985.1 - 5.4e-05 22.6 15.4 0.033 13.8 0.1 4.6 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.28 GAM23985.1 - 0.021 14.4 0.2 0.5 10.0 0.0 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 GAM23985.1 - 0.056 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.28 GAM23985.1 - 3.5 8.0 17.0 6.2 7.2 0.3 6.4 5 2 1 6 6 6 0 Leucine Rich Repeat NEP PF10167.4 GAM23986.1 - 6.3e-30 103.3 4.1 6.3e-30 103.3 2.9 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein DUF651 PF04895.7 GAM23986.1 - 0.064 12.8 0.1 0.18 11.4 0.0 1.9 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) ATG16 PF08614.6 GAM23987.1 - 0.0042 16.9 9.8 0.0042 16.9 6.8 4.7 1 1 2 4 4 4 1 Autophagy protein 16 (ATG16) DASH_Hsk3 PF08227.6 GAM23987.1 - 0.093 12.9 0.7 0.093 12.9 0.5 4.0 5 0 0 5 5 5 0 DASH complex subunit Hsk3 like Filament PF00038.16 GAM23987.1 - 0.17 11.3 49.5 0.0091 15.4 15.0 3.1 1 1 1 2 2 2 0 Intermediate filament protein CENP-F_leu_zip PF10473.4 GAM23987.1 - 0.21 11.4 61.9 0.016 15.0 14.8 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 GAM23987.1 - 0.75 9.2 51.1 1.1 8.6 13.8 4.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF869 PF05911.6 GAM23987.1 - 1.2 7.3 48.8 0.1 10.8 7.6 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 GAM23987.1 - 3.2 6.8 16.3 0.21 10.7 1.6 2.7 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF2968 PF11180.3 GAM23987.1 - 4.2 6.7 40.6 0.45 9.8 9.7 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2968) AAA_13 PF13166.1 GAM23987.1 - 7.4 4.9 46.5 0.68 8.3 26.4 2.5 1 1 1 2 2 2 0 AAA domain TRADD_N PF09034.5 GAM23988.1 - 0.085 12.8 0.2 0.085 12.8 0.2 2.6 2 1 1 3 3 3 0 TRADD, N-terminal domain Fmp27_WPPW PF10359.4 GAM23988.1 - 0.34 9.2 26.7 0.44 8.9 8.8 3.2 1 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain Allexi_40kDa PF05549.6 GAM23988.1 - 1.1 8.4 18.8 0.65 9.2 4.7 3.3 3 1 0 3 3 3 0 Allexivirus 40kDa protein Yos1 PF08571.5 GAM23989.1 - 1.5e-18 66.6 3.0 1.8e-18 66.3 2.1 1.1 1 0 0 1 1 1 1 Yos1-like YtxH PF12732.2 GAM23990.1 - 0.0016 18.7 5.2 0.15 12.4 3.1 2.4 1 1 0 1 1 1 1 YtxH-like protein Pex19 PF04614.7 GAM23990.1 - 0.019 14.5 8.6 0.024 14.2 5.9 1.2 1 0 0 1 1 1 0 Pex19 protein family Apolipoprotein PF01442.13 GAM23990.1 - 0.03 13.8 1.3 0.041 13.3 0.9 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain WXG100 PF06013.7 GAM23990.1 - 0.03 14.3 0.8 0.33 10.9 0.1 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG CSF-1 PF05337.6 GAM23990.1 - 0.057 12.7 3.5 0.072 12.4 2.5 1.1 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) DUF2229 PF09989.4 GAM23990.1 - 0.14 11.6 0.4 0.19 11.1 0.3 1.3 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Prominin PF05478.6 GAM23990.1 - 0.18 9.3 0.8 0.2 9.1 0.6 1.2 1 0 0 1 1 1 0 Prominin Cytochrom_C_2 PF01322.15 GAM23990.1 - 1.4 9.4 6.1 7.9 7.0 1.1 2.2 1 1 1 2 2 2 0 Cytochrome C' Peptidase_C1 PF00112.18 GAM23991.1 - 9.5e-73 244.6 3.4 9.5e-73 244.6 2.4 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM23991.1 - 5e-12 45.9 6.1 8.6e-12 45.1 4.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM23991.1 - 3.6e-05 22.4 0.5 0.02 13.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF896 PF05979.7 GAM23991.1 - 1.8 8.2 4.8 0.5 9.9 0.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DEAD PF00270.24 GAM23992.1 - 2.4e-49 167.0 0.0 6.3e-49 165.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM23992.1 - 5.4e-19 67.8 0.1 1.7e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 GAM23992.1 - 2e-11 43.5 7.4 2e-11 43.5 5.1 3.6 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Alba PF01918.16 GAM23993.1 - 4.3e-11 42.2 0.0 7.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 GAM23993.1 - 6.7e-06 25.8 0.2 0.15 11.7 0.0 2.8 1 1 2 3 3 3 2 Rpp20 subunit of nuclear RNase MRP and P SSP160 PF06933.6 GAM23993.1 - 0.051 11.5 16.7 0.065 11.2 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.6 GAM23993.1 - 0.21 11.6 5.5 0.33 10.9 3.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.6 GAM23993.1 - 0.61 7.8 7.1 0.71 7.6 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HemX PF04375.9 GAM23993.1 - 2.5 6.6 7.3 3.8 6.0 5.1 1.1 1 0 0 1 1 1 0 HemX TMEM154 PF15102.1 GAM23993.1 - 3.1 7.4 5.8 6.2 6.5 4.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mucin PF01456.12 GAM23993.1 - 8 6.2 28.1 15 5.3 19.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.20 GAM23994.1 - 1e-17 64.5 0.0 1.5e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM23994.1 - 3.5e-12 46.6 0.0 4.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM23994.1 - 8.1e-06 25.6 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM23994.1 - 0.0005 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAM23994.1 - 0.0043 17.0 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 GAM23994.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 GAM23994.1 - 0.12 12.2 0.1 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DSPc PF00782.15 GAM23995.1 - 3.9e-29 100.9 1.0 8.2e-29 99.8 0.7 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 GAM23995.1 - 1.8e-06 28.2 0.2 0.0022 18.3 0.0 3.2 3 0 0 3 3 3 2 Rhodanese-like domain PTPlike_phytase PF14566.1 GAM23995.1 - 2.9e-05 24.1 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 GAM23995.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 GAM23995.1 - 0.041 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 GAM23995.1 - 0.14 12.4 0.2 0.55 10.4 0.0 2.0 2 1 0 2 2 2 0 Tyrosine phosphatase family Apolipoprotein PF01442.13 GAM23997.1 - 1.5e-15 57.2 40.8 2.8e-08 33.5 5.1 5.2 3 2 1 4 4 4 3 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 GAM23997.1 - 6.2e-05 22.8 44.7 0.029 14.1 3.0 6.9 3 2 3 7 7 7 5 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.3 GAM23997.1 - 0.005 16.8 3.1 0.005 16.8 2.2 6.3 3 2 4 7 7 7 2 YlqD protein DNA_pol_lambd_f PF10391.4 GAM23997.1 - 0.0089 15.5 1.3 0.23 11.0 0.1 4.0 3 1 0 3 3 3 1 Fingers domain of DNA polymerase lambda DUF883 PF05957.8 GAM23997.1 - 0.013 15.9 42.9 3.4 8.1 1.7 9.4 4 2 5 10 10 10 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 GAM23997.1 - 0.035 14.0 16.5 13 5.8 0.0 7.1 4 2 2 6 6 6 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Prominin PF05478.6 GAM23997.1 - 0.089 10.3 48.9 0.18 9.2 6.9 4.4 3 1 1 4 4 4 0 Prominin Sec8_exocyst PF04048.9 GAM23997.1 - 0.15 11.7 45.3 0.016 14.8 3.4 6.5 4 2 3 7 7 7 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.6 GAM23997.1 - 3.6 7.5 69.1 0.19 11.7 6.7 7.4 4 2 4 8 8 8 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.7 GAM23997.1 - 9.4 6.0 41.1 1.9 8.2 4.8 6.6 3 2 5 8 8 8 0 Protein of unknown function (DUF1664) DUF1446 PF07287.6 GAM23998.1 - 2.8e-34 118.1 0.0 3.5e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Njmu-R1 PF15053.1 GAM23999.1 - 4.6e-25 88.1 9.2 2.5e-22 79.1 1.5 3.0 2 2 1 3 3 3 3 Mjmu-R1-like protein family BiPBP_C PF06832.7 GAM24000.1 - 0.0054 16.6 0.0 7.8 6.5 0.0 3.4 3 0 0 3 3 3 2 Penicillin-Binding Protein C-terminus Family Y_Y_Y PF07495.8 GAM24000.1 - 0.032 13.9 2.7 1.6 8.5 0.0 4.6 5 0 0 5 5 5 0 Y_Y_Y domain MRF_C2 PF13888.1 GAM24002.1 - 0.024 14.4 3.0 0.033 14.0 0.5 2.4 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 FNIP PF05725.7 GAM24003.1 - 7.1e-09 35.4 6.3 1.4e-05 24.9 0.7 5.2 5 2 1 6 6 6 3 FNIP Repeat LRR_5 PF13306.1 GAM24003.1 - 0.97 9.1 4.0 8.2 6.1 0.1 2.8 3 0 0 3 3 3 0 Leucine rich repeats (6 copies) FNIP PF05725.7 GAM24004.1 - 0.054 13.4 3.2 0.82 9.6 0.0 2.9 3 1 0 3 3 3 0 FNIP Repeat Ins_allergen_rp PF06757.8 GAM24006.1 - 0.053 12.9 0.4 0.27 10.7 0.1 2.1 1 1 1 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification TIG PF01833.19 GAM24007.1 - 9.9e-14 51.1 43.5 2.2e-06 27.5 1.2 6.5 6 0 0 6 6 6 4 IPT/TIG domain EGF_2 PF07974.8 GAM24007.1 - 0.00056 20.0 14.6 0.0013 18.8 10.1 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.22 GAM24007.1 - 2.5 8.1 11.2 5.5 7.0 7.8 1.6 1 0 0 1 1 1 0 EGF-like domain Kelch_6 PF13964.1 GAM24009.1 - 2.1e-09 37.1 4.9 1.7e-05 24.7 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM24009.1 - 2.8e-09 36.5 0.9 0.00012 21.7 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24009.1 - 4.7e-06 26.0 1.5 0.0016 17.9 0.1 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM24009.1 - 3.6e-05 23.7 4.3 0.0012 18.9 0.0 4.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24009.1 - 0.00052 19.8 10.6 0.43 10.5 0.4 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM24009.1 - 0.51 10.1 5.5 1.1 9.1 0.1 3.3 4 0 0 4 4 4 0 Kelch motif FNIP PF05725.7 GAM24010.1 - 7.8e-60 198.5 23.2 6e-12 45.3 0.0 8.0 2 2 7 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 GAM24010.1 - 1.8e-05 24.5 4.3 2 8.4 0.0 6.2 2 1 5 7 7 7 2 Protein of unknown function (DUF1769) F-box-like PF12937.2 GAM24010.1 - 0.059 13.0 0.2 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 F-box-like Acyl-CoA_dh_1 PF00441.19 GAM24011.1 - 3.5e-47 160.2 0.5 5.1e-47 159.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM24011.1 - 6.6e-28 97.5 0.0 1.2e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 GAM24011.1 - 1.3e-19 70.7 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM24011.1 - 2.9e-19 68.3 0.1 5.6e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain HhH-GPD PF00730.20 GAM24011.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein AhpC-TSA_2 PF13911.1 GAM24012.1 - 2.7e-18 65.9 0.0 4.8e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAM24012.1 - 4.6e-05 23.1 0.0 9.2e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM24012.1 - 0.0088 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin YdjO PF14169.1 GAM24013.1 - 0.012 15.0 0.3 0.042 13.3 0.0 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO Sugar_tr PF00083.19 GAM24014.1 - 8e-96 321.3 36.4 3.1e-95 319.3 25.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM24014.1 - 3.7e-40 137.7 61.2 1.1e-30 106.5 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 GAM24014.1 - 3.3e-05 22.5 8.5 3.3e-05 22.5 5.9 2.9 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like MFS_3 PF05977.8 GAM24014.1 - 0.05 11.7 8.0 0.02 13.0 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector GHMP_kinases_N PF00288.21 GAM24015.1 - 3.7e-07 30.1 2.2 7.9e-07 29.0 1.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Metallophos PF00149.23 GAM24016.1 - 6.6e-12 45.2 2.7 3.5e-11 42.8 1.9 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM24016.1 - 1.6e-10 41.0 3.1 5e-10 39.4 2.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 GAM24016.1 - 3.9e-10 39.3 0.0 1.5e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily PTPS PF01242.14 GAM24017.1 - 3.6e-34 117.0 0.3 4.1e-34 116.9 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DUF3276 PF11680.3 GAM24017.1 - 0.053 13.3 0.1 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Kelch_4 PF13418.1 GAM24018.1 - 2.9e-35 119.8 11.7 3.4e-07 29.9 0.0 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24018.1 - 6.3e-32 108.8 12.7 1.8e-08 33.7 0.1 6.2 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 GAM24018.1 - 5e-30 102.4 21.3 2.5e-08 33.7 0.0 7.4 4 2 2 6 6 6 5 Kelch motif Kelch_3 PF13415.1 GAM24018.1 - 4.1e-29 100.0 20.5 1.6e-08 34.4 0.1 8.0 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM24018.1 - 1.9e-28 97.1 7.2 3.3e-05 23.4 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 GAM24018.1 - 1.5e-24 85.4 13.2 4.6e-05 23.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif BTB PF00651.26 GAM24018.1 - 2.1e-24 85.6 2.3 1.1e-22 80.1 0.4 2.4 1 1 1 2 2 2 1 BTB/POZ domain DUF3342 PF11822.3 GAM24018.1 - 8.1e-05 21.9 0.7 0.00039 19.6 0.2 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3342) BACK PF07707.10 GAM24018.1 - 0.0063 16.3 1.7 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Pkinase_Tyr PF07714.12 GAM24019.1 - 1.2e-55 188.4 0.0 1.5e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM24019.1 - 1.7e-47 161.8 0.0 2.3e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 GAM24019.1 - 0.047 12.7 0.1 0.11 11.5 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAP PF02037.22 GAM24020.1 - 0.0011 18.3 0.2 0.0023 17.3 0.1 1.5 1 0 0 1 1 1 1 SAP domain Nop14 PF04147.7 GAM24020.1 - 0.0027 15.7 14.7 0.0032 15.4 10.2 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 GAM24020.1 - 0.049 12.9 11.4 0.06 12.6 7.9 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 GAM24020.1 - 0.15 11.0 15.8 0.19 10.7 11.0 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 GAM24020.1 - 0.22 9.9 15.6 0.26 9.7 10.8 1.1 1 0 0 1 1 1 0 Daxx Family SURF2 PF05477.6 GAM24020.1 - 0.22 10.6 9.8 0.29 10.2 6.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) YL1 PF05764.8 GAM24020.1 - 0.25 10.9 15.1 0.37 10.3 10.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Merozoite_SPAM PF07133.6 GAM24020.1 - 0.29 11.0 20.5 0.47 10.3 14.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.9 GAM24020.1 - 0.54 8.2 9.4 0.66 7.9 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 GAM24020.1 - 0.63 9.0 10.5 0.84 8.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2890 PF11081.3 GAM24020.1 - 0.67 9.9 11.1 1 9.3 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 GAM24020.1 - 8.4 5.5 9.2 12 5.0 6.4 1.3 1 0 0 1 1 1 0 NOA36 protein Chromo PF00385.19 GAM24021.1 - 4.5e-15 55.0 0.3 4.5e-15 55.0 0.2 2.4 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 GAM24021.1 - 2.8e-05 24.2 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 GAM24022.1 - 9.3e-11 41.4 0.1 2.2e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 GAM24025.1 - 0.00011 21.6 0.0 0.00011 21.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 GAM24026.1 - 2.5e-54 184.1 0.0 2.2e-53 181.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24026.1 - 6.3e-53 179.4 0.0 9.3e-53 178.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RA PF00788.18 GAM24026.1 - 0.00055 20.3 0.0 0.0062 17.0 0.0 2.8 3 1 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Dicty_REP PF05086.7 GAM24026.1 - 0.012 13.4 13.0 0.023 12.5 9.0 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YL1 PF05764.8 GAM24026.1 - 0.023 14.2 2.2 5.1 6.6 0.0 3.0 2 1 0 2 2 2 0 YL1 nuclear protein APH PF01636.18 GAM24026.1 - 0.07 12.8 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3439 PF11921.3 GAM24026.1 - 5.2 6.8 15.5 16 5.2 8.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hpt PF01627.18 GAM24027.1 - 4.1e-11 42.7 0.1 6.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Hpt domain PPR_1 PF12854.2 GAM24027.1 - 0.001 18.5 0.3 0.001 18.5 0.2 1.7 2 0 0 2 2 2 1 PPR repeat PPR PF01535.15 GAM24027.1 - 0.024 14.5 0.2 0.024 14.5 0.1 2.0 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.1 GAM24027.1 - 0.046 13.6 0.9 0.069 13.1 0.1 1.8 2 0 0 2 2 2 0 PPR repeat family KNOX2 PF03791.8 GAM24027.1 - 0.26 10.5 1.6 1.8 7.9 0.1 2.6 3 0 0 3 3 3 0 KNOX2 domain BAF1_ABF1 PF04684.8 GAM24027.1 - 5.9 5.6 12.3 1.9 7.2 5.2 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.8 GAM24027.1 - 6.2 6.6 20.6 9.1 6.0 14.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SEC-C PF02810.10 GAM24028.1 - 6.9e-08 31.8 2.6 1.3e-07 30.9 1.8 1.5 1 0 0 1 1 1 1 SEC-C motif PseudoU_synth_2 PF00849.17 GAM24029.1 - 6.6e-13 48.8 0.7 3.4e-12 46.4 0.0 2.5 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.20 GAM24029.1 - 2.8e-07 29.8 0.0 7.1e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 S4 domain E1-E2_ATPase PF00122.15 GAM24030.1 - 4.3e-18 65.1 1.1 5.8e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM24030.1 - 4.3e-16 59.9 0.0 4.4e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM24030.1 - 8.9e-14 52.0 0.0 2.2e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM24030.1 - 3.7e-12 46.0 0.0 7.8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM24030.1 - 0.0012 18.4 0.2 0.02 14.4 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.27 GAM24031.1 - 1.2 8.6 3.7 0.97 8.9 0.7 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 GAM24031.1 - 3.1 7.4 7.0 0.53 9.9 1.4 2.3 2 0 0 2 2 2 0 EF-hand domain pair PLDc_2 PF13091.1 GAM24032.1 - 4.9e-32 110.3 0.0 1.7e-18 66.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM24032.1 - 5.8e-08 32.2 0.6 3.7e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Spc97_Spc98 PF04130.8 GAM24033.1 - 9.4e-123 410.3 4.1 9.4e-123 410.3 2.9 2.4 3 0 0 3 3 3 1 Spc97 / Spc98 family CoA_binding PF02629.14 GAM24033.1 - 0.085 13.3 0.1 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Caprin-1_C PF12287.3 GAM24034.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term 2OG-FeII_Oxy PF03171.15 GAM24034.1 - 0.073 13.3 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Transpos_assoc PF13963.1 GAM24036.1 - 0.075 13.0 0.3 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Transposase-associated domain Ank_2 PF12796.2 GAM24038.1 - 0.00025 21.3 0.0 0.47 10.8 0.0 4.0 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM24038.1 - 0.049 14.1 0.6 35 5.0 0.0 4.6 4 1 1 5 5 5 0 Ankyrin repeats (many copies) Peptidase_M66 PF10462.4 GAM24039.1 - 1.5e-61 207.9 0.2 1.9e-61 207.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.1 GAM24039.1 - 0.00058 19.4 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAM24039.1 - 0.002 18.6 0.2 0.0068 16.9 0.2 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 GAM24039.1 - 0.0032 17.4 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Metallo-peptidase family M12 Metallopep PF12044.3 GAM24039.1 - 0.0034 15.9 0.1 0.0055 15.2 0.1 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.1 GAM24039.1 - 0.0048 16.9 1.9 0.011 15.8 1.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EphA2_TM PF14575.1 GAM24039.1 - 0.063 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M10 PF00413.19 GAM24039.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Matrixin 2OG-FeII_Oxy_3 PF13640.1 GAM24040.1 - 7.6e-06 26.3 0.0 0.00022 21.6 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24040.1 - 0.00014 22.1 0.0 0.00043 20.5 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 GAM24040.1 - 0.0099 14.9 13.9 0.016 14.3 9.6 1.2 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.9 GAM24040.1 - 0.46 8.4 8.4 0.78 7.7 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein 2OG-FeII_Oxy PF03171.15 GAM24041.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM24041.1 - 0.00016 22.0 0.0 0.00045 20.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3246 PF11596.3 GAM24041.1 - 0.00069 18.9 10.9 0.0012 18.2 7.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) BSP_II PF05432.6 GAM24041.1 - 0.049 12.9 13.9 0.082 12.1 9.6 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 GAM24041.1 - 0.13 10.2 7.6 0.23 9.4 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 GAM24041.1 - 1.6 7.3 26.5 3.2 6.3 18.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.8 GAM24041.1 - 4.4 7.0 24.5 0.33 10.8 13.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_3 PF13640.1 GAM24042.1 - 8.4e-05 23.0 0.0 0.00023 21.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24042.1 - 0.0002 21.5 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Autophagy_N PF03986.8 GAM24042.1 - 1.9 8.2 8.9 3.7 7.3 6.2 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF2946 PF11162.3 GAM24043.1 - 0.41 10.8 3.9 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) 2OG-FeII_Oxy PF03171.15 GAM24044.1 - 0.00016 21.9 0.0 0.00066 19.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM24044.1 - 0.0015 19.0 0.0 0.0039 17.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CdCA1 PF10563.4 GAM24044.1 - 0.05 13.1 0.1 0.05 13.1 0.1 2.0 3 0 0 3 3 3 0 Cadmium carbonic anhydrase repeat DUF3142 PF11340.3 GAM24044.1 - 0.057 13.0 0.9 0.41 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) 2OG-FeII_Oxy_3 PF13640.1 GAM24045.1 - 2.1e-05 24.9 0.1 7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24045.1 - 0.00011 22.3 0.0 0.00034 20.8 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sporozoite_P67 PF05642.6 GAM24045.1 - 0.036 11.9 6.0 0.058 11.2 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TLP-20 PF06088.6 GAM24045.1 - 5 6.7 15.7 0.29 10.7 6.8 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) 2OG-FeII_Oxy_3 PF13640.1 GAM24046.1 - 5.2e-06 26.8 0.0 1.1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24046.1 - 3e-05 24.2 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM24047.1 - 2.7e-05 24.6 0.0 7.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24047.1 - 0.00016 21.8 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.5 GAM24047.1 - 1.8 7.5 23.9 3.8 6.4 16.6 1.5 1 0 0 1 1 1 0 BUD22 2OG-FeII_Oxy_3 PF13640.1 GAM24048.1 - 2e-05 25.0 0.0 4.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24048.1 - 0.0002 21.5 0.0 0.00047 20.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM24050.1 - 7.7e-05 23.1 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24050.1 - 0.00028 21.1 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM24051.1 - 1.3e-05 25.6 0.0 3.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM24051.1 - 6.2e-05 23.2 0.0 0.00029 21.0 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Herpes_UL32 PF06070.6 GAM24051.1 - 0.1 11.0 4.1 0.14 10.6 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 TIG PF01833.19 GAM24052.1 - 4.2e-11 42.6 15.1 2.7e-07 30.4 2.1 7.5 4 1 3 7 7 7 5 IPT/TIG domain TIG PF01833.19 GAM24053.1 - 1.4e-16 60.2 37.2 4.6e-07 29.7 2.7 6.8 4 2 2 6 6 6 6 IPT/TIG domain Kelch_4 PF13418.1 GAM24054.1 - 4.6e-41 138.3 19.4 9.6e-11 41.2 0.1 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24054.1 - 7.8e-41 137.3 18.5 2e-08 34.1 0.0 7.4 7 1 1 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24054.1 - 1.1e-33 114.6 8.8 6.6e-08 32.3 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM24054.1 - 5.8e-31 105.3 15.5 2.4e-06 27.4 0.3 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM24054.1 - 2.3e-29 100.0 19.2 3.4e-06 26.5 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM24054.1 - 3.4e-29 100.1 15.4 7.6e-08 31.7 0.1 6.4 6 0 0 6 6 6 5 Kelch motif SAM_2 PF07647.12 GAM24054.1 - 4.6e-16 58.4 0.2 8.8e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM24054.1 - 4.2e-13 49.2 0.3 7.8e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF605 PF04652.11 GAM24054.1 - 0.35 10.2 31.0 0.67 9.2 21.5 1.4 1 0 0 1 1 1 0 Vta1 like DUF1220 PF06758.8 GAM24054.1 - 1.7 8.4 3.9 32 4.4 0.4 2.8 1 1 1 2 2 2 0 Repeat of unknown function (DUF1220) Dicty_REP PF05086.7 GAM24054.1 - 1.9 6.1 14.2 2.8 5.5 9.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 GAM24054.1 - 3.6 7.3 16.0 5.2 6.8 11.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 GAM24055.1 - 7.9e-84 272.8 24.9 1.5e-13 50.0 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM24055.1 - 2.4e-10 39.1 4.0 0.007 14.5 0.0 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM24055.1 - 0.00024 19.9 0.8 0.25 10.0 0.0 3.5 2 2 2 4 4 4 2 Nup133 N terminal like LisH PF08513.6 GAM24055.1 - 0.00064 19.3 0.2 0.0012 18.4 0.2 1.5 1 0 0 1 1 1 1 LisH DUF342 PF03961.8 GAM24055.1 - 0.035 12.5 1.2 0.052 11.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) LSM PF01423.17 GAM24056.1 - 2.4e-12 46.2 1.2 3.6e-12 45.6 0.8 1.3 1 0 0 1 1 1 1 LSM domain LRR19-TM PF15176.1 GAM24057.1 - 0.14 11.8 1.1 0.24 11.0 0.2 1.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain EGF_2 PF07974.8 GAM24057.1 - 2 8.6 14.1 4.8 7.4 9.8 1.7 1 0 0 1 1 1 0 EGF-like domain Metallophos PF00149.23 GAM24058.1 - 7.6e-41 139.7 0.5 1.2e-40 139.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 GAM24058.1 - 0.052 13.5 0.1 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region PAH PF02671.16 GAM24058.1 - 0.064 12.8 0.1 17 5.0 0.0 3.4 4 0 0 4 4 4 0 Paired amphipathic helix repeat CDK2AP PF09806.4 GAM24058.1 - 0.79 9.9 3.6 1.4 9.0 2.5 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein dCMP_cyt_deam_1 PF00383.17 GAM24059.1 - 4.4e-13 48.7 0.1 1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAM24059.1 - 0.046 13.5 0.2 3.3 7.5 0.1 2.3 1 1 0 1 1 1 0 Bd3614-like deaminase Cys_rich_KTR PF14205.1 GAM24059.1 - 0.3 10.5 2.7 0.57 9.6 0.4 2.4 2 1 0 2 2 2 0 Cysteine-rich KTR PhnA_Zn_Ribbon PF08274.7 GAM24059.1 - 2 8.2 4.6 79 3.1 0.0 3.5 2 1 0 2 2 2 0 PhnA Zinc-Ribbon PAP_assoc PF03828.14 GAM24060.1 - 1.4e-07 31.3 0.4 4e-07 29.8 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAM24060.1 - 4.7e-06 26.8 0.0 1.2e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain TIM PF00121.13 GAM24061.1 - 1.8e-89 299.0 0.1 2e-89 298.8 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 GAM24061.1 - 0.028 13.6 0.0 1.9 7.7 0.0 2.1 1 1 1 2 2 2 0 CutC family DUF1084 PF06454.6 GAM24062.1 - 1.9e-09 36.9 17.7 3.2e-09 36.2 12.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.8 GAM24062.1 - 0.048 13.8 11.8 0.1 12.7 8.2 1.6 1 0 0 1 1 1 0 EGF-like domain EB PF01683.13 GAM24062.1 - 1 9.4 7.7 1.9 8.6 5.3 1.4 1 0 0 1 1 1 0 EB module DUF1129 PF06570.6 GAM24062.1 - 1.3 8.3 10.1 0.023 14.0 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HMG_CoA_synt_C PF08540.5 GAM24063.1 - 9.6e-87 291.0 0.3 1.5e-86 290.4 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 GAM24063.1 - 2.3e-85 284.4 0.2 3.6e-85 283.8 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 GAM24063.1 - 0.087 12.8 0.0 3.3 7.7 0.0 3.2 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Beta-lactamase PF00144.19 GAM24064.1 - 3.7e-59 200.3 0.0 5.6e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Ubie_methyltran PF01209.13 GAM24065.1 - 1.1e-18 67.2 0.0 1.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAM24065.1 - 2.2e-18 66.5 0.0 5.4e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM24065.1 - 7.6e-17 61.3 0.0 9.8e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM24065.1 - 5.7e-11 42.7 0.0 9.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM24065.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM24065.1 - 3.7e-09 36.8 0.0 7.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM24065.1 - 3.9e-09 37.0 0.0 7.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAM24065.1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM24065.1 - 0.0021 17.6 0.0 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 GAM24065.1 - 0.0077 16.2 0.0 0.021 14.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM24065.1 - 0.008 15.5 0.1 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAM24065.1 - 0.022 13.7 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase TrkA_N PF02254.13 GAM24065.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain CMAS PF02353.15 GAM24065.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 GAM24065.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Phosphorylase PF00343.15 GAM24066.1 - 0 1116.9 0.9 0 1116.7 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1546 PF07571.8 GAM24067.1 - 2.8e-31 107.4 0.1 7.4e-31 106.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 GAM24067.1 - 4.6e-30 103.3 0.2 8.2e-30 102.5 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 GAM24067.1 - 0.00024 21.1 0.2 0.00053 20.0 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Vps8 PF12816.2 GAM24067.1 - 0.015 14.5 1.0 0.028 13.6 0.7 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 CBFD_NFYB_HMF PF00808.18 GAM24067.1 - 0.016 15.2 0.9 0.026 14.5 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Serglycin PF04360.7 GAM24067.1 - 0.032 13.9 1.5 0.058 13.1 1.1 1.3 1 0 0 1 1 1 0 Serglycin Homeobox_KN PF05920.6 GAM24068.1 - 2e-07 30.6 0.7 4.3e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 GAM24068.1 - 6.6e-07 28.8 0.1 6.6e-07 28.8 0.1 2.7 3 0 0 3 3 3 1 Homeobox domain DDE_Tnp_IS240 PF13610.1 GAM24068.1 - 0.0024 17.8 1.4 0.0049 16.8 1.0 1.5 1 0 0 1 1 1 1 DDE domain PAH PF02671.16 GAM24068.1 - 0.015 14.9 0.1 0.042 13.4 0.1 1.8 1 0 0 1 1 1 0 Paired amphipathic helix repeat 2Fe-2S_thioredx PF01257.14 GAM24069.1 - 8.7e-58 194.0 0.1 1.1e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Carboxyl_trans PF01039.17 GAM24071.1 - 3.1e-193 642.6 0.1 3.6e-193 642.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CM_2 PF01817.16 GAM24071.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Chorismate mutase type II MdcE PF06833.6 GAM24071.1 - 0.13 11.4 0.1 0.47 9.6 0.0 1.9 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) LSM PF01423.17 GAM24072.1 - 1.1e-06 28.0 0.1 1.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain AAA_17 PF13207.1 GAM24074.1 - 2.6e-05 25.0 2.0 0.00067 20.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 GAM24074.1 - 0.0038 17.1 1.5 0.89 9.4 0.0 2.3 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_18 PF13238.1 GAM24074.1 - 0.0068 16.7 0.7 0.13 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain CPT PF07931.7 GAM24074.1 - 0.13 11.9 0.5 4.5 6.8 0.1 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ICE2 PF08426.5 GAM24075.1 - 0.042 12.4 0.9 0.068 11.7 0.6 1.2 1 0 0 1 1 1 0 ICE2 BAF1_ABF1 PF04684.8 GAM24075.1 - 2.7 6.7 14.1 4.1 6.1 9.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hydrolase_4 PF12146.3 GAM24077.1 - 4.6e-24 84.0 0.0 1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 GAM24077.1 - 5.5e-23 82.0 0.0 7.8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM24077.1 - 1.7e-19 70.0 0.0 3.1e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM24077.1 - 2.2e-06 27.3 0.9 0.00019 21.0 0.7 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 GAM24077.1 - 4e-05 23.1 0.2 0.00014 21.4 0.0 1.9 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 GAM24077.1 - 4e-05 23.1 0.0 0.86 8.9 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM24077.1 - 5.5e-05 22.4 1.9 0.017 14.3 0.0 3.5 3 1 0 3 3 3 1 Prolyl oligopeptidase family AXE1 PF05448.7 GAM24077.1 - 0.00021 19.8 0.0 0.0041 15.6 0.0 2.6 4 0 0 4 4 4 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 GAM24077.1 - 0.0014 18.2 0.9 0.0065 16.0 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.15 GAM24077.1 - 0.021 14.2 0.3 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Thioesterase PF00975.15 GAM24077.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain DUF3377 PF11857.3 GAM24077.1 - 9 6.0 8.4 0.51 10.0 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Asp_protease PF09668.5 GAM24079.1 - 1e-54 183.3 0.1 1.6e-54 182.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 GAM24079.1 - 1.2e-11 43.7 0.5 6.7e-11 41.4 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin family Asp_protease_2 PF13650.1 GAM24079.1 - 8.9e-09 35.7 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 GAM24079.1 - 3.9e-07 29.7 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 GAM24079.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 GAM24079.1 - 0.00031 20.4 0.7 0.0012 18.6 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain RVP PF00077.15 GAM24079.1 - 0.00066 19.5 0.1 0.0052 16.6 0.0 2.5 2 1 0 2 2 2 1 Retroviral aspartyl protease UBA_4 PF14555.1 GAM24079.1 - 0.0037 16.7 0.1 0.0097 15.4 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain DUF3347 PF11827.3 GAM24079.1 - 0.034 14.1 4.6 0.064 13.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Rad60-SLD PF11976.3 GAM24079.1 - 0.059 13.0 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FNIP PF05725.7 GAM24080.1 - 2.3e-44 149.0 13.5 2.8e-15 55.9 0.3 5.1 2 1 2 6 6 6 5 FNIP Repeat DUF1769 PF08588.5 GAM24080.1 - 1.3e-05 24.9 1.8 2.5 8.0 0.0 5.6 1 1 5 6 6 6 2 Protein of unknown function (DUF1769) TetR_C_5 PF08360.6 GAM24080.1 - 0.079 12.9 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region TIG PF01833.19 GAM24081.1 - 2e-46 155.8 153.3 2.1e-07 30.8 6.4 16.3 13 3 3 16 16 16 13 IPT/TIG domain Ank_2 PF12796.2 GAM24084.1 - 2.9e-11 43.5 0.6 3.5e-05 24.0 0.1 4.3 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24084.1 - 1.5e-07 30.9 0.4 1.6 9.2 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 GAM24084.1 - 0.00011 22.5 0.3 5.5 7.6 0.1 5.4 6 1 2 8 8 8 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM24084.1 - 0.0076 16.4 0.9 0.64 10.3 0.0 4.3 4 2 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM24084.1 - 0.016 15.0 3.1 20 5.1 0.0 5.7 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.2 GAM24086.1 - 7.1e-20 71.1 11.3 4.5e-06 26.9 0.1 4.0 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24086.1 - 1e-13 50.0 17.1 0.23 11.8 0.0 9.0 5 3 4 9 9 9 5 Ankyrin repeat Ank PF00023.25 GAM24086.1 - 1.5e-12 46.6 12.1 0.24 11.2 0.1 8.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 GAM24086.1 - 2.4e-12 47.0 14.2 0.0044 17.4 0.2 6.1 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM24086.1 - 5.4e-11 42.3 10.7 0.18 12.1 0.0 7.7 4 3 4 8 8 8 5 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM24086.1 - 0.0015 18.2 4.1 0.55 10.0 0.0 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3447) Ank_5 PF13857.1 GAM24087.1 - 0.014 15.6 0.0 1.7 8.9 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM24087.1 - 0.032 14.5 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24087.1 - 0.057 13.6 0.0 0.52 10.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat DUF260 PF03195.9 GAM24087.1 - 0.069 13.4 0.1 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF260 Ank_4 PF13637.1 GAM24087.1 - 0.073 13.6 0.2 1.2 9.7 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Noc2 PF03715.8 GAM24088.1 - 3.2e-90 302.0 5.0 3.2e-90 302.0 3.5 2.7 4 0 0 4 4 4 1 Noc2p family YafO_toxin PF13957.1 GAM24089.1 - 0.035 13.9 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system TATR PF03430.8 GAM24089.1 - 0.41 9.2 4.5 0.4 9.2 3.1 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Sigma70_ner PF04546.8 GAM24089.1 - 0.44 10.1 6.0 0.43 10.1 4.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 GAM24089.1 - 0.88 7.5 7.3 0.88 7.5 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein MTBP_N PF14918.1 GAM24089.1 - 1 8.6 5.4 1.1 8.5 3.8 1.0 1 0 0 1 1 1 0 MDM2-binding Tom22 PF04281.8 GAM24089.1 - 4.4 6.8 7.4 6.1 6.3 5.2 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Metallophos PF00149.23 GAM24090.1 - 3e-10 39.8 0.2 1.6e-09 37.4 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM24090.1 - 0.0011 18.8 0.1 0.0053 16.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3487 PF11990.3 GAM24090.1 - 0.012 14.9 0.0 0.012 14.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) Syntaxin-6_N PF09177.6 GAM24091.1 - 8.3e-21 74.2 0.2 8.3e-21 74.2 0.1 2.1 3 0 0 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 GAM24091.1 - 1.2e-11 44.0 0.9 1.2e-11 44.0 0.7 2.2 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 GAM24091.1 - 0.00026 20.4 3.1 0.00045 19.7 1.8 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 EMP24_GP25L PF01105.19 GAM24091.1 - 0.037 13.7 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RRF_GI PF12614.3 GAM24091.1 - 0.041 13.6 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF3753 PF12575.3 GAM24091.1 - 0.058 13.1 1.5 0.16 11.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) MRVI1 PF05781.7 GAM24091.1 - 0.062 11.6 1.2 0.087 11.2 0.7 1.3 1 1 0 1 1 1 0 MRVI1 protein Pro-kuma_activ PF09286.6 GAM24091.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain MCPVI PF02993.9 GAM24091.1 - 0.58 10.2 2.7 0.58 10.2 0.1 1.9 2 0 0 2 2 2 0 Minor capsid protein VI P12 PF12669.2 GAM24091.1 - 1.7 8.9 3.8 3.1 8.0 2.6 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family adh_short PF00106.20 GAM24092.1 - 1.9e-20 73.4 0.0 2.4e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM24092.1 - 1.4e-10 41.0 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 GAM24092.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 GAM24092.1 - 0.0086 15.0 0.2 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 GAM24092.1 - 0.012 15.3 0.6 0.017 14.7 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 GAM24092.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Saccharop_dh PF03435.13 GAM24092.1 - 0.1 11.5 0.2 0.16 10.9 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM24092.1 - 0.12 12.1 0.3 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 GAM24093.1 - 2.8e-24 85.9 0.5 4e-24 85.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM24093.1 - 1.2e-11 44.5 0.2 1.9e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM24093.1 - 5.3e-06 26.5 0.1 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAM24093.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF218 PF02698.12 GAM24093.1 - 0.073 12.5 0.2 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 DUF218 domain Mo25 PF08569.6 GAM24094.1 - 7.8e-128 426.2 14.1 8.7e-128 426.0 9.8 1.0 1 0 0 1 1 1 1 Mo25-like HMA PF00403.21 GAM24095.1 - 8.2e-12 45.0 1.7 1e-11 44.7 1.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1677 PF07911.8 GAM24095.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Cullin_binding PF03556.10 GAM24096.1 - 5.2e-30 103.9 0.9 7.6e-30 103.4 0.6 1.2 1 0 0 1 1 1 1 Cullin binding Ndc1_Nup PF09531.5 GAM24096.1 - 0.028 12.8 4.0 0.029 12.8 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.4 GAM24096.1 - 1 7.5 8.1 1.1 7.4 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein SRP-alpha_N PF04086.8 GAM24096.1 - 7.6 5.8 14.0 13 5.0 9.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_transf_8 PF01501.15 GAM24097.1 - 1.4e-12 47.5 0.6 2.3e-12 46.7 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 GAM24097.1 - 0.0042 16.8 0.1 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1462 PF07315.6 GAM24097.1 - 0.054 13.4 0.4 0.74 9.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1462) YtfJ_HI0045 PF09695.5 GAM24097.1 - 0.11 11.8 0.5 0.21 10.8 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) DUF562 PF04763.7 GAM24097.1 - 0.12 11.6 0.6 0.82 8.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF562) YorP PF09629.5 GAM24097.1 - 0.46 10.5 2.8 6.8 6.7 0.1 2.7 3 0 0 3 3 3 0 YorP protein UCH PF00443.24 GAM24098.1 - 1.4e-67 227.6 0.0 1.4e-67 227.6 0.0 3.5 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAM24098.1 - 4.4e-20 71.9 0.0 4.4e-20 71.9 0.0 4.0 5 0 0 5 5 5 1 DUSP domain UCH_1 PF13423.1 GAM24098.1 - 2.9e-07 30.2 1.4 0.00027 20.4 0.1 3.9 3 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Abhydrolase_6 PF12697.2 GAM24099.1 - 4.7e-25 88.7 0.0 6.1e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM24099.1 - 3.2e-15 56.3 0.0 6.6e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM24099.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM24099.1 - 6.2e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 GAM24099.1 - 0.0037 16.1 0.0 0.0072 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.15 GAM24099.1 - 0.015 14.7 0.2 0.095 12.1 0.1 2.2 2 1 0 2 2 2 0 Putative esterase Lipase_3 PF01764.20 GAM24099.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) SapB_1 PF05184.10 GAM24100.1 - 4.4e-06 26.3 4.6 5.8e-06 25.9 0.6 2.6 2 0 0 2 2 2 1 Saposin-like type B, region 1 DUF806 PF05657.6 GAM24100.1 - 0.082 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF806) zf-Apc11 PF12861.2 GAM24100.1 - 0.64 9.8 5.4 4.7 7.1 0.0 3.0 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger GST_C_3 PF14497.1 GAM24101.1 - 2.2e-11 44.0 0.0 3.8e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM24101.1 - 7.5e-10 38.5 0.1 1.4e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM24101.1 - 9.1e-06 25.8 0.0 7.9e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM24101.1 - 0.00044 20.1 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM24101.1 - 0.0062 16.5 0.1 0.033 14.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TIG PF01833.19 GAM24102.1 - 0.00018 21.4 15.4 0.00029 20.7 5.5 4.7 4 0 0 4 4 4 1 IPT/TIG domain FLgD_tudor PF13861.1 GAM24102.1 - 0.00058 19.8 0.0 2.2 8.3 0.0 5.5 5 2 0 5 5 5 1 FlgD Tudor-like domain Qn_am_d_aIII PF09099.5 GAM24102.1 - 0.17 12.2 28.5 1.5 9.1 0.1 8.0 8 1 0 8 8 8 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Sec7 PF01369.15 GAM24103.1 - 1.6e-58 197.4 0.0 1.6e-58 197.4 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 GAM24103.1 - 3.2e-07 30.4 1.7 0.00012 22.2 0.2 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 GAM24103.1 - 6.3e-06 26.4 6.4 0.00017 21.8 0.1 2.9 3 0 0 3 3 3 2 Pleckstrin homology domain DUF605 PF04652.11 GAM24103.1 - 0.23 10.8 14.4 0.37 10.1 10.0 1.3 1 0 0 1 1 1 0 Vta1 like Calreticulin PF00262.13 GAM24104.1 - 4.7e-116 387.4 12.9 4.7e-116 387.4 8.9 1.7 2 0 0 2 2 2 1 Calreticulin family RPN7 PF10602.4 GAM24105.1 - 1.5e-49 167.7 1.3 1.1e-40 138.8 0.8 2.6 1 1 1 2 2 2 2 26S proteasome subunit RPN7 PCI PF01399.22 GAM24105.1 - 3.2e-18 65.9 1.7 7.1e-18 64.8 0.5 2.1 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.23 GAM24105.1 - 0.011 15.3 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GGDN PF05165.7 GAM24105.1 - 0.013 14.6 0.1 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 GGDN family TPR_12 PF13424.1 GAM24105.1 - 0.016 15.1 0.0 0.075 12.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1875 PF08961.5 GAM24105.1 - 0.026 13.8 0.3 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) TPR_7 PF13176.1 GAM24105.1 - 0.032 14.0 0.1 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SUV3_C PF12513.3 GAM24105.1 - 0.033 13.6 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal TPR_8 PF13181.1 GAM24105.1 - 0.045 13.5 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24105.1 - 0.12 12.3 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.10 GAM24106.1 - 3.1e-213 709.2 0.0 4.2e-213 708.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 GAM24106.1 - 8.4e-21 73.5 0.0 1.9e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 GAM24106.1 - 3.7e-15 56.1 0.0 8.8e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain RabGAP-TBC PF00566.13 GAM24107.1 - 1.5e-28 99.7 10.0 1.5e-26 93.2 7.0 3.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Calici_MSP PF05752.6 GAM24107.1 - 0.13 11.8 2.7 0.33 10.5 1.7 1.9 1 1 1 2 2 2 0 Calicivirus minor structural protein LUC7 PF03194.10 GAM24107.1 - 0.31 10.5 1.1 0.54 9.7 0.8 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Macoilin PF09726.4 GAM24107.1 - 4.8 5.3 11.4 1.9 6.6 2.4 2.4 2 1 0 2 2 2 0 Transmembrane protein TRAP_beta PF05753.9 GAM24108.1 - 9.2e-39 132.4 0.3 1.1e-38 132.2 0.2 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF2146 PF10220.4 GAM24109.1 - 1e-52 179.3 16.5 1.5e-31 109.2 1.6 4.1 2 2 1 4 4 4 3 Uncharacterized conserved protein (DUF2146) Macoilin PF09726.4 GAM24109.1 - 0.02 13.2 7.2 0.033 12.4 5.0 1.4 1 0 0 1 1 1 0 Transmembrane protein Mitofilin PF09731.4 GAM24109.1 - 0.11 11.1 8.0 0.19 10.3 5.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dicty_REP PF05086.7 GAM24110.1 - 0.00043 18.1 9.5 0.00043 18.1 6.6 4.5 3 1 0 4 4 4 1 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 GAM24111.1 - 5e-72 242.1 0.0 7.6e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24111.1 - 4.7e-52 176.6 0.0 8.7e-52 175.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Treacle PF03546.9 GAM24111.1 - 0.082 11.6 0.6 0.13 11.0 0.4 1.2 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Mst1_SARAH PF11629.3 GAM24111.1 - 0.093 12.5 1.3 0.24 11.2 0.9 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 RasGAP PF00616.14 GAM24112.1 - 8.2e-43 146.3 2.8 6e-42 143.5 0.0 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF1992 PF09350.5 GAM24112.1 - 0.033 14.0 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1992) tRNA-synt_His PF13393.1 GAM24112.1 - 0.27 10.2 5.5 0.22 10.5 1.4 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Arf PF00025.16 GAM24113.1 - 1.6e-45 154.4 0.0 2e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM24113.1 - 4.4e-20 71.7 0.0 5.4e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24113.1 - 1.3e-12 48.2 0.0 2.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 GAM24113.1 - 1.8e-10 40.1 0.1 2.4e-08 33.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM24113.1 - 3.6e-10 39.3 0.0 5.8e-10 38.6 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM24113.1 - 2.1e-09 37.3 0.0 4.4e-09 36.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM24113.1 - 1.1e-07 31.2 0.0 1.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAM24113.1 - 1.6e-05 24.3 0.0 0.00094 18.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 GAM24113.1 - 0.025 14.2 0.1 0.045 13.4 0.1 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM24113.1 - 0.032 14.0 0.0 0.84 9.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 GAM24113.1 - 0.037 13.3 0.5 0.077 12.2 0.2 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 GAM24113.1 - 0.05 13.7 0.0 0.33 11.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain VPS9 PF02204.13 GAM24114.1 - 1e-19 70.4 0.1 1.2e-18 66.9 0.1 2.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.19 GAM24114.1 - 1.7e-18 66.4 1.0 1.7e-18 66.4 0.7 2.4 2 0 0 2 2 2 1 PX domain Ras PF00071.17 GAM24114.1 - 1.2e-09 37.8 0.0 2.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ras family CUE PF02845.11 GAM24114.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 CUE domain HTH_Tnp_4 PF13613.1 GAM24114.1 - 0.047 13.2 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease FNIP PF05725.7 GAM24115.1 - 2.1e-82 270.8 42.5 2.1e-12 46.7 0.1 10.7 6 2 2 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 GAM24115.1 - 5.7e-05 22.9 5.6 6 6.8 0.0 7.3 5 3 3 8 8 8 2 Protein of unknown function (DUF1769) Pro_isomerase PF00160.16 GAM24116.1 - 3.8e-41 140.8 0.0 3.8e-41 140.8 0.0 2.4 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Dicty_REP PF05086.7 GAM24116.1 - 0.028 12.1 20.8 0.038 11.7 14.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4604 PF15377.1 GAM24116.1 - 0.033 14.3 1.7 0.033 14.3 1.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4604) Presenilin PF01080.12 GAM24116.1 - 2.8 6.6 11.5 4.1 6.1 8.0 1.4 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 GAM24116.1 - 3.2 5.9 16.7 4 5.6 11.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_C1 PF00112.18 GAM24117.1 - 6.8e-42 143.8 1.8 9.8e-42 143.2 1.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.21 GAM24117.1 - 0.012 16.0 0.7 0.029 14.8 0.0 1.9 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Response_reg PF00072.19 GAM24118.1 - 8.6e-20 70.8 0.0 9.4e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.1 GAM24119.1 - 2.9e-32 112.1 0.0 1e-31 110.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain HATPase_c PF02518.21 GAM24119.1 - 8.4e-27 93.0 0.2 2.1e-26 91.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 GAM24119.1 - 1.5e-21 76.6 0.0 4.8e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.20 GAM24119.1 - 1.1e-16 60.5 0.1 3.5e-16 58.9 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase_Tyr PF07714.12 GAM24119.1 - 1.3e-14 53.9 0.0 5.8e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase GAF PF01590.21 GAM24119.1 - 6.1e-13 49.1 0.0 2.2e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 GAM24119.1 - 3.6e-10 40.0 0.0 1.3e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 GAM24119.1 - 8.2e-06 26.3 0.0 4.5e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 GAF domain AAA_22 PF13401.1 GAM24119.1 - 0.00015 21.9 0.0 0.0015 18.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM24119.1 - 0.00035 20.3 0.3 0.0021 17.7 0.2 2.3 1 1 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 GAM24119.1 - 0.0027 16.6 0.4 0.036 12.9 0.3 2.4 1 1 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 GAM24119.1 - 0.019 14.8 1.6 7.1 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 GAM24119.1 - 0.028 15.2 0.0 0.13 13.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM24119.1 - 0.039 14.2 0.5 0.32 11.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain PUA PF01472.15 GAM24120.1 - 1.2e-07 31.2 0.1 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 PUA domain Peptidase_C1 PF00112.18 GAM24123.1 - 1.2e-49 169.1 4.9 2.5e-49 168.1 3.4 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 GAM24123.1 - 4.6e-05 22.1 0.5 0.0037 15.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.7 GAM24124.1 - 1.9e-11 44.0 6.1 4.1e-11 42.9 4.2 1.6 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) BCS1_N PF08740.6 GAM24124.1 - 0.0093 15.5 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal RhoGAP PF00620.22 GAM24125.1 - 9.8e-34 116.1 0.1 9.8e-34 116.1 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.13 GAM24126.1 - 1.2e-05 24.8 0.2 1.7e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 BAR domain Taxilin PF09728.4 GAM24126.1 - 0.018 14.1 1.0 0.026 13.6 0.7 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein TMP-TENI PF02581.12 GAM24126.1 - 0.05 12.7 0.1 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI p450 PF00067.17 GAM24127.1 - 1.9e-75 254.2 0.0 2.2e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VWA_3 PF13768.1 GAM24128.1 - 1.3e-31 109.3 0.0 1.1e-30 106.3 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 GAM24128.1 - 2.6e-22 78.7 1.0 6.1e-22 77.5 0.7 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAM24128.1 - 1.8e-13 50.6 0.0 1e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 GAM24128.1 - 2e-13 50.7 0.0 4.9e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 GAM24128.1 - 2.2e-05 24.3 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VIT_2 PF13757.1 GAM24128.1 - 0.00019 20.8 0.1 0.00042 19.7 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Prenyltrans_1 PF13243.1 GAM24128.1 - 0.058 13.4 0.0 19 5.3 0.0 2.8 2 0 0 2 2 2 0 Prenyltransferase-like TP53IP5 PF15331.1 GAM24128.1 - 0.51 10.2 5.5 0.087 12.7 0.6 1.9 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 FNIP PF05725.7 GAM24129.1 - 9e-17 60.7 11.9 3.8e-06 26.7 0.0 6.0 4 2 1 6 6 6 4 FNIP Repeat GFA PF04828.9 GAM24131.1 - 2.7e-08 33.6 1.8 2.7e-08 33.6 1.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-P11 PF03854.9 GAM24131.1 - 0.44 10.0 0.1 0.44 10.0 0.1 2.6 2 1 0 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.1 GAM24131.1 - 1.3 8.8 9.5 2.7 7.7 5.1 2.5 2 1 0 2 2 2 0 zinc-RING finger domain Ank_2 PF12796.2 GAM24132.1 - 1.6e-19 70.0 0.0 1.7e-18 66.7 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM24132.1 - 8.5e-18 63.1 0.3 5.6e-10 38.5 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 GAM24132.1 - 4.9e-17 61.5 1.8 6.6e-10 38.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM24132.1 - 2.3e-14 53.4 0.3 9.2e-07 29.2 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24132.1 - 7e-12 44.3 0.2 1.5e-05 24.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat RA PF00788.18 GAM24132.1 - 5.5e-08 33.1 0.0 9.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RRM_6 PF14259.1 GAM24132.1 - 0.11 12.4 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pet191_N PF10203.4 GAM24133.1 - 1.1 9.3 10.7 1.5 8.9 0.1 2.9 3 1 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Pribosyltran_N PF13793.1 GAM24134.1 - 2.5e-43 146.4 0.9 4.9e-42 142.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM24134.1 - 2.5e-33 115.4 8.5 2.5e-31 108.8 1.6 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM24134.1 - 1.1e-05 25.0 4.9 1.9e-05 24.3 2.2 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain Chlorosome_CsmC PF11098.3 GAM24134.1 - 0.34 10.5 4.4 0.14 11.8 1.2 1.7 2 0 0 2 2 2 0 Chlorosome envelope protein C L51_S25_CI-B8 PF05047.11 GAM24135.1 - 8.5e-11 41.4 0.1 1.3e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NAD_binding_4 PF07993.7 GAM24136.1 - 3.2e-19 68.8 0.2 2e-18 66.2 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM24136.1 - 2e-18 66.7 0.2 3.1e-18 66.0 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM24136.1 - 7.7e-18 64.1 0.0 1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 GAM24136.1 - 3.3e-11 43.5 0.3 4.5e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM24136.1 - 1.4e-07 31.0 0.1 2.6e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 GAM24136.1 - 0.0001 22.0 0.2 0.00026 20.7 0.1 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM24136.1 - 0.00014 20.8 0.7 0.00022 20.2 0.2 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM24136.1 - 0.0002 21.3 0.3 0.00078 19.3 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAM24136.1 - 0.0009 18.2 0.5 0.0015 17.5 0.3 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 GAM24136.1 - 0.0019 18.5 0.2 0.0046 17.2 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 GAM24136.1 - 0.04 13.8 0.0 0.09 12.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TMEM213 PF15192.1 GAM24137.1 - 1.5 8.8 16.4 0.56 10.2 1.2 3.0 1 1 2 3 3 3 0 TMEM213 family CobU PF02283.11 GAM24143.1 - 0.061 12.7 0.1 5.8 6.2 0.0 2.1 1 1 1 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RFC1 PF08519.7 GAM24143.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain zf-CDGSH PF09360.5 GAM24145.1 - 1.3e-16 60.1 14.1 2.7e-11 43.0 0.8 2.8 3 0 0 3 3 3 2 Iron-binding zinc finger CDGSH type Phage_H_T_join PF05521.6 GAM24145.1 - 0.03 14.5 0.2 0.046 14.0 0.2 1.2 1 0 0 1 1 1 0 Phage head-tail joining protein GcrA PF07750.6 GAM24145.1 - 5.1 7.2 6.1 1.3 9.1 0.1 2.2 1 1 1 2 2 2 0 GcrA cell cycle regulator UDG PF03167.14 GAM24146.1 - 6.4e-27 93.8 0.0 9.6e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Dicty_REP PF05086.7 GAM24146.1 - 0.0012 16.7 12.1 0.0015 16.4 8.4 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein BUD22 PF09073.5 GAM24146.1 - 2.2 7.2 22.0 3.2 6.7 15.2 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 GAM24146.1 - 3.6 7.0 18.0 5.9 6.3 12.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 GAM24146.1 - 7 4.5 12.1 9.5 4.1 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 GAM24146.1 - 8.6 4.9 11.1 12 4.4 7.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RhoGEF PF00621.15 GAM24147.1 - 4e-48 163.6 1.5 1.1e-47 162.2 1.0 1.8 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAM24147.1 - 1.2e-16 60.3 10.7 2.7e-16 59.2 7.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAM24147.1 - 2.5e-12 46.9 0.2 6.8e-12 45.5 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 GAM24147.1 - 0.0013 18.5 1.0 0.0031 17.3 0.1 2.1 2 0 0 2 2 2 1 PH domain Na_Ca_ex PF01699.19 GAM24148.1 - 9.5e-17 60.9 22.6 2.8e-11 43.1 8.6 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein PBP1_TM PF14812.1 GAM24148.1 - 0.042 14.1 0.1 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peroxin-3 PF04882.7 GAM24148.1 - 0.071 11.8 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Peroxin-3 Pox_A14 PF05767.7 GAM24148.1 - 0.076 12.9 1.7 0.18 11.8 0.1 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 FNIP PF05725.7 GAM24149.1 - 2.1e-58 194.0 20.7 6.8e-11 41.9 0.0 9.7 7 1 2 10 10 10 8 FNIP Repeat LRR_7 PF13504.1 GAM24149.1 - 0.073 13.3 9.0 1.6e+02 3.2 0.0 7.9 9 0 0 9 9 9 0 Leucine rich repeat FAM177 PF14774.1 GAM24150.1 - 3.2e-15 56.1 1.2 4.4e-15 55.7 0.8 1.2 1 0 0 1 1 1 1 FAM177 family DUF2967 PF11179.3 GAM24150.1 - 0.078 12.4 0.9 0.089 12.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) TSA PF03249.8 GAM24150.1 - 0.11 11.0 5.8 0.12 10.8 4.0 1.0 1 0 0 1 1 1 0 Type specific antigen DUF605 PF04652.11 GAM24150.1 - 0.55 9.5 6.6 0.28 10.5 3.4 1.4 1 1 0 1 1 1 0 Vta1 like dsDNA_bind PF01984.15 GAM24150.1 - 1.1 9.2 9.5 0.17 11.8 2.5 2.0 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Pex14_N PF04695.8 GAM24150.1 - 2.4 8.1 8.6 0.11 12.5 1.8 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA_pol PF00940.14 GAM24151.1 - 5.4e-165 548.7 0.0 2.1e-164 546.8 0.0 1.8 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 GAM24151.1 - 6.5e-49 166.9 0.1 1e-48 166.2 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal SIN1 PF05422.7 GAM24152.1 - 0.0063 15.0 0.1 0.026 13.0 0.0 2.0 2 0 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) DPBB_1 PF03330.13 GAM24153.1 - 2.1e-12 46.8 0.1 4.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAM24153.1 - 0.006 16.5 0.6 0.014 15.3 0.4 1.6 1 1 0 1 1 1 1 Cerato-platanin Ribosomal_L1 PF00687.16 GAM24154.1 - 1.6e-31 109.3 2.0 1.6e-31 109.3 1.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family G10 PF01125.12 GAM24155.1 - 0.00024 20.7 37.5 0.00055 19.5 13.0 2.4 2 0 0 2 2 2 2 G10 protein cobW PF02492.14 GAM24156.1 - 2.9e-08 33.3 2.9 0.00081 18.8 0.1 2.6 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 GAM24156.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 GAM24156.1 - 0.014 14.8 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 GAM24156.1 - 0.037 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 GAM24156.1 - 0.038 13.7 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 GAM24156.1 - 0.073 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 GAM24156.1 - 0.13 12.1 1.0 0.43 10.3 0.1 2.2 2 0 0 2 2 2 0 Dynamin family CobW_C PF07683.9 GAM24156.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Gcd10p PF04189.8 GAM24157.1 - 8.8e-65 218.7 0.4 8.8e-65 218.7 0.2 2.8 3 0 0 3 3 3 1 Gcd10p family Ku_N PF03731.10 GAM24158.1 - 1.3e-27 96.7 0.1 1.6e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 GAM24159.1 - 7.5e-41 139.7 1.1 3.1e-40 137.7 0.0 2.1 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 GAM24159.1 - 3.4e-13 49.5 3.7 7.6e-13 48.3 2.6 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain zf-CCHH PF10283.4 GAM24159.1 - 7.7e-09 35.2 2.9 1.4e-08 34.4 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif Ku_C PF03730.9 GAM24159.1 - 1.4e-07 31.8 0.6 1.4e-07 31.8 0.4 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 GAM24159.1 - 0.015 14.8 0.1 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 SAP domain Mucin PF01456.12 GAM24159.1 - 3.2 7.5 22.0 0.36 10.6 11.7 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein NUP50 PF08911.6 GAM24160.1 - 0.016 15.5 0.5 0.036 14.4 0.4 1.5 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Ribosomal_L35p PF01632.14 GAM24160.1 - 0.069 13.0 4.7 1.9 8.4 0.3 2.4 2 0 0 2 2 2 0 Ribosomal protein L35 Endonuc_BglI PF14562.1 GAM24160.1 - 0.15 10.8 0.2 0.22 10.3 0.2 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglI Dynamin_N PF00350.18 GAM24162.1 - 5.3e-22 78.4 2.7 1.2e-20 74.0 0.0 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM24162.1 - 7.7e-05 22.6 0.1 0.00029 20.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM24162.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM24162.1 - 0.11 12.8 4.3 0.15 12.3 0.0 3.1 3 0 0 3 3 3 0 ABC transporter SNARE_assoc PF09335.6 GAM24164.1 - 1.8e-30 105.6 4.4 1.8e-30 105.6 3.1 1.8 2 1 0 2 2 2 1 SNARE associated Golgi protein TMEM154 PF15102.1 GAM24164.1 - 0.0013 18.4 0.2 0.0025 17.5 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF996 PF06195.8 GAM24164.1 - 0.05 13.5 0.7 0.05 13.5 0.5 2.2 1 1 1 3 3 3 0 Protein of unknown function (DUF996) RseC_MucC PF04246.7 GAM24164.1 - 0.26 10.8 1.0 3.3 7.3 0.2 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1129 PF06570.6 GAM24164.1 - 0.51 9.6 8.2 0.46 9.7 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF898 PF05987.8 GAM24164.1 - 2.2 7.0 9.2 0.19 10.5 0.3 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Lectin_C PF00059.16 GAM24165.1 - 2.8e-06 27.8 0.6 2e-05 25.1 0.3 2.3 2 1 0 2 2 2 1 Lectin C-type domain TIG PF01833.19 GAM24165.1 - 4.1e-05 23.4 8.4 0.00051 19.9 0.8 2.9 2 1 0 2 2 2 2 IPT/TIG domain TIG PF01833.19 GAM24166.1 - 5.5e-09 35.9 21.1 2.4e-06 27.4 5.5 3.7 3 1 1 4 4 4 2 IPT/TIG domain EB PF01683.13 GAM24166.1 - 0.018 15.1 3.3 0.038 14.0 2.3 1.6 1 0 0 1 1 1 0 EB module EGF_2 PF07974.8 GAM24166.1 - 0.029 14.5 6.8 0.075 13.2 4.7 1.7 1 0 0 1 1 1 0 EGF-like domain DUF2093 PF09866.4 GAM24166.1 - 0.13 11.4 0.4 0.23 10.6 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) LysM PF01476.15 GAM24167.1 - 0.01 15.7 0.2 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 LysM domain Coiled PF05710.7 GAM24168.1 - 0.00035 20.9 11.6 0.00051 20.4 8.0 1.2 1 0 0 1 1 1 1 Coiled coil TPR_11 PF13414.1 GAM24169.1 - 2.2e-32 110.4 27.1 2e-09 36.9 1.3 5.1 2 2 4 6 6 6 6 TPR repeat TPR_1 PF00515.23 GAM24169.1 - 1.1e-21 75.3 4.3 0.00027 20.3 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24169.1 - 6.7e-19 66.2 8.0 4e-05 23.1 0.0 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24169.1 - 2.2e-17 63.2 1.7 1.3e-06 28.9 0.1 4.8 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24169.1 - 2.4e-17 61.6 14.7 0.00014 21.7 0.3 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24169.1 - 2.8e-17 61.6 6.3 0.00045 20.6 0.1 6.7 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24169.1 - 1.2e-15 57.5 12.6 0.00042 20.5 1.1 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 GAM24169.1 - 7.1e-13 48.4 7.0 0.0032 17.5 0.1 5.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24169.1 - 1.1e-11 44.5 8.8 0.031 14.2 0.0 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24169.1 - 2.1e-08 33.3 4.9 2.5 8.1 0.0 5.8 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM24169.1 - 5e-07 29.7 4.1 0.019 15.0 1.4 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM24169.1 - 2e-06 27.5 2.8 0.043 13.6 0.0 3.7 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24169.1 - 4.2e-06 26.1 6.0 0.9 9.4 0.2 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM24169.1 - 0.00092 19.5 6.8 6.3 7.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 GAM24169.1 - 0.0012 17.6 0.6 0.096 11.4 0.0 2.2 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 GAM24169.1 - 0.013 15.7 1.2 0.26 11.6 0.1 2.9 3 0 0 3 3 3 0 Bacterial transcriptional activator domain DUF4248 PF14053.1 GAM24169.1 - 0.025 14.1 1.1 0.12 11.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Coatomer_E PF04733.9 GAM24169.1 - 0.042 13.0 0.4 0.46 9.6 0.0 2.3 2 0 0 2 2 2 0 Coatomer epsilon subunit OmdA PF13376.1 GAM24169.1 - 0.08 12.6 0.2 15 5.3 0.0 3.5 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated TOM20_plant PF06552.7 GAM24169.1 - 0.086 12.4 1.1 5.9 6.4 0.1 3.1 2 2 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 FNIP PF05725.7 GAM24170.1 - 2.7e-33 113.6 6.1 2.3e-13 49.8 0.3 5.4 4 1 1 6 6 6 5 FNIP Repeat Ery_res_leader2 PF08057.6 GAM24170.1 - 0.028 14.4 0.3 1.7 8.8 0.1 3.2 3 0 0 3 3 3 0 Erythromycin resistance leader peptide FNIP PF05725.7 GAM24171.1 - 6.3e-05 22.8 2.6 0.0022 17.9 0.1 2.6 1 1 1 2 2 2 2 FNIP Repeat Cid2 PF09774.4 GAM24172.1 - 5e-08 33.1 5.3 6.2e-08 32.8 3.7 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 SR-25 PF10500.4 GAM24172.1 - 0.0057 16.1 7.2 0.0058 16.1 5.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF515 PF04415.7 GAM24172.1 - 0.0098 14.1 2.7 0.011 14.0 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF515) eIF-4B PF06273.6 GAM24172.1 - 0.046 12.4 0.3 0.059 12.1 0.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Striatin PF08232.7 GAM24172.1 - 0.14 12.5 2.5 0.17 12.1 1.7 1.2 1 0 0 1 1 1 0 Striatin family Pex14_N PF04695.8 GAM24172.1 - 0.15 12.0 3.0 0.21 11.6 2.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4602 PF15375.1 GAM24172.1 - 0.28 11.2 2.3 0.41 10.7 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) FlxA PF14282.1 GAM24172.1 - 1.2 9.0 11.3 0.47 10.4 4.8 2.1 1 1 1 2 2 2 0 FlxA-like protein Kinesin PF00225.18 GAM24173.1 - 7.7e-93 310.8 2.1 7.7e-93 310.8 1.5 3.5 3 1 0 3 3 3 1 Kinesin motor domain Viral_helicase1 PF01443.13 GAM24174.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Snf7 PF03357.16 GAM24175.1 - 7.2e-23 80.8 15.8 7.2e-23 80.8 10.9 1.4 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 GAM24175.1 - 0.0018 17.6 6.2 0.003 16.9 4.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SAS4 PF15460.1 GAM24175.1 - 1.7 8.5 7.5 0.18 11.6 0.3 2.6 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 Fib_alpha PF08702.5 GAM24175.1 - 7.6 6.6 15.1 0.48 10.5 2.2 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YlqD PF11068.3 GAM24175.1 - 7.9 6.5 17.8 3.3 7.7 0.8 2.7 1 1 0 2 2 2 0 YlqD protein DUF3573 PF12097.3 GAM24175.1 - 9.1 4.7 8.8 15 4.0 5.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) AdoHcyase PF05221.12 GAM24176.1 - 5.5e-141 468.1 0.0 6.4e-141 467.9 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 GAM24176.1 - 3.8e-85 283.7 4.7 5.9e-85 283.0 3.3 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 GAM24176.1 - 8.9e-07 28.2 0.2 2.1e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 GAM24176.1 - 0.0062 15.9 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 GAM24176.1 - 0.0086 15.6 0.2 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 GAM24176.1 - 0.05 13.6 0.2 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 GAM24176.1 - 0.053 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 GAM24176.1 - 0.055 13.1 0.2 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM24176.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 GAM24176.1 - 0.12 12.2 1.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Glyco_transf_10 PF00852.14 GAM24177.1 - 3.2e-34 118.0 0.3 4.9e-34 117.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Laminin_G_3 PF13385.1 GAM24177.1 - 8.2e-25 87.8 0.1 1.5e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TFCD_C PF12612.3 GAM24178.1 - 1.6e-25 89.6 4.5 2.7e-25 88.9 0.2 3.2 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 GAM24178.1 - 7.7e-11 41.1 0.0 0.033 14.2 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 GAM24178.1 - 3e-09 37.0 1.5 0.38 11.0 0.0 5.5 4 2 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 GAM24178.1 - 1.1e-05 25.7 0.8 53 4.4 0.0 6.8 6 0 0 6 6 6 0 HEAT-like repeat Arm PF00514.18 GAM24178.1 - 0.0027 17.4 0.3 3.7 7.5 0.0 5.3 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Band_7_1 PF13421.1 GAM24178.1 - 0.026 14.0 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family GTP_EFTU PF00009.22 GAM24182.1 - 8.1e-61 204.7 0.7 1.3e-60 204.1 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAM24182.1 - 5.9e-25 86.9 0.1 1.2e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 GAM24182.1 - 5.8e-21 74.1 0.0 1.6e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 GAM24182.1 - 1.2e-11 44.5 1.7 5e-11 42.5 0.3 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 GAM24182.1 - 9.9e-11 41.2 0.0 2.4e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 GAM24182.1 - 0.00015 21.6 0.0 0.00038 20.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase OAS1_C PF10421.4 GAM24183.1 - 3.8e-14 52.6 1.4 6.2e-14 51.9 1.0 1.3 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NFRKB_winged PF14465.1 GAM24183.1 - 0.046 13.5 1.5 4.1 7.2 0.0 2.8 2 1 1 3 3 3 0 NFRKB Winged Helix-like Glucodextran_B PF09136.5 GAM24184.1 - 0.11 12.6 0.0 13 5.9 0.0 2.9 3 0 0 3 3 3 0 Glucodextranase, domain B F-box-like PF12937.2 GAM24185.1 - 0.086 12.5 0.3 0.46 10.2 0.3 2.0 2 0 0 2 2 2 0 F-box-like Peptidase_M1 PF01433.15 GAM24186.1 - 5.9e-64 216.5 0.0 9.1e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 GAM24186.1 - 2.5e-40 137.3 0.0 5.2e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 GAM24186.1 - 3.1e-15 56.3 0.0 8.2e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Trp_dioxygenase PF03301.8 GAM24187.1 - 6.7e-115 383.8 6.7 8.3e-115 383.5 4.7 1.0 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase PCI PF01399.22 GAM24187.1 - 0.059 13.6 1.2 0.19 12.0 0.8 1.8 2 0 0 2 2 2 0 PCI domain DUF2179 PF10035.4 GAM24187.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF2746 PF10874.3 GAM24187.1 - 0.23 11.6 1.9 11 6.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) DNA_pol_A PF00476.15 GAM24188.1 - 3.3e-57 193.8 1.1 1.3e-56 191.9 0.0 2.5 2 1 1 3 3 3 1 DNA polymerase family A 5_3_exonuc_N PF02739.11 GAM24188.1 - 2.9e-39 134.1 0.0 8.6e-39 132.6 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 GAM24188.1 - 3.2e-27 94.6 0.1 1.5e-26 92.5 0.1 2.3 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.15 GAM24188.1 - 1.7e-11 43.8 0.0 4.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease DUF2122 PF09895.4 GAM24188.1 - 0.019 15.1 0.1 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) HHH_5 PF14520.1 GAM24188.1 - 0.062 13.4 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH PF00633.18 GAM24188.1 - 0.18 11.6 0.2 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Myb_DNA-binding PF00249.26 GAM24190.1 - 6.8e-22 77.2 11.5 2.8e-12 46.5 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM24190.1 - 6.5e-19 67.7 5.2 4.3e-11 42.7 0.9 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain PHD PF00628.24 GAM24190.1 - 0.0013 18.3 7.2 0.0059 16.2 5.0 2.2 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 GAM24190.1 - 0.34 10.6 9.1 0.016 14.9 1.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 EGF_MSP1_1 PF12946.2 GAM24190.1 - 0.6 9.9 3.5 1.5 8.6 2.4 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 PAS PF00989.19 GAM24190.1 - 1.5 8.6 7.1 43 3.9 0.0 2.5 2 0 0 2 2 2 0 PAS fold STAS PF01740.16 GAM24192.1 - 1.6e-18 66.2 0.0 2.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 STAS domain EcoRI_methylase PF13651.1 GAM24192.1 - 0.088 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI IMS PF00817.15 GAM24193.1 - 4.2e-39 133.7 0.0 7.2e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 GAM24193.1 - 0.0027 17.6 0.1 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 IMS family HHH motif SmpA_OmlA PF04355.8 GAM24193.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 SmpA / OmlA family HHH_5 PF14520.1 GAM24193.1 - 0.059 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Shigella_OspC PF06128.6 GAM24194.1 - 0.2 11.0 3.1 0.4 10.1 2.1 1.4 1 0 0 1 1 1 0 Shigella flexneri OspC protein SIR2 PF02146.12 GAM24194.1 - 1.2 8.8 8.4 0.049 13.3 0.4 2.3 2 1 0 2 2 2 0 Sir2 family IncA PF04156.9 GAM24194.1 - 3.8 7.0 57.8 0.069 12.7 7.3 4.2 3 1 1 4 4 4 0 IncA protein UQ_con PF00179.21 GAM24195.1 - 1.7e-46 157.1 0.0 1.9e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM24195.1 - 0.00025 20.7 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAM24195.1 - 0.044 13.4 0.0 0.09 12.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain G8 PF10162.4 GAM24196.1 - 3.2e-27 94.8 0.1 8.2e-27 93.4 0.0 1.8 1 0 0 1 1 1 1 G8 domain Mito_carr PF00153.22 GAM24197.1 - 4.9e-73 240.9 1.6 2e-24 85.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAM24197.1 - 7e-26 90.1 10.5 2.6e-14 53.0 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM24197.1 - 1.8e-22 76.8 13.2 5.7e-06 25.2 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.1 GAM24197.1 - 2.3e-22 77.2 13.9 4.4e-06 25.7 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 GAM24197.1 - 6.4e-19 66.0 6.5 4.6e-05 22.9 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 GAM24197.1 - 1.2e-18 66.4 8.3 1.2e-06 28.0 0.1 4.4 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM24197.1 - 1.7e-13 50.5 1.8 6.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM24197.1 - 8.5e-07 28.5 3.6 0.077 12.6 0.0 4.0 4 1 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 GAM24197.1 - 0.073 12.8 6.7 0.96 9.2 0.2 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAM24197.1 - 0.14 12.0 0.3 5.3 7.0 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain CRM1_C PF08767.6 GAM24198.1 - 0.081 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal DUF4051 PF13260.1 GAM24199.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) HEAT_2 PF13646.1 GAM24200.1 - 0.00039 20.6 0.0 0.0016 18.6 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 GAM24200.1 - 0.0076 16.2 0.0 0.022 14.8 0.0 1.8 1 0 0 1 1 1 1 HEAT repeat Arm PF00514.18 GAM24200.1 - 0.027 14.3 0.0 0.071 12.9 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAM24200.1 - 0.029 14.8 0.0 0.065 13.7 0.0 1.6 1 0 0 1 1 1 0 HEAT-like repeat RasGEF_N_2 PF14663.1 GAM24200.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RRM_1 PF00076.17 GAM24201.1 - 1.6e-16 59.6 0.3 4.6e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM24201.1 - 2.7e-11 43.2 0.1 5.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM24201.1 - 4.6e-09 35.9 0.3 8.9e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Poxvirus_B22R PF04395.7 GAM24201.1 - 0.27 10.7 11.1 0.82 9.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus B22R protein CPSase_L_D2 PF02786.12 GAM24203.1 - 3.4e-76 255.2 0.2 1.2e-75 253.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAM24203.1 - 6.2e-45 151.8 0.0 1.2e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM24203.1 - 3.6e-37 126.6 0.0 8.4e-37 125.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 GAM24203.1 - 5.6e-16 57.9 2.2 5.6e-16 57.9 1.5 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 GAM24203.1 - 2.6e-13 50.1 0.0 5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM24203.1 - 4.3e-13 48.7 0.0 2.1e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 GAM24203.1 - 4.2e-12 45.8 0.0 1e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 GAM24203.1 - 1.3e-11 44.1 0.0 6.3e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 GAM24203.1 - 4.9e-08 32.5 0.3 6.1e-05 22.6 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 GAM24203.1 - 4.8e-06 26.5 0.0 1.6e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.1 GAM24203.1 - 6.3e-05 22.6 0.1 0.00022 20.8 0.1 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain RimK PF08443.6 GAM24203.1 - 0.00092 18.7 0.0 0.0091 15.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 GAM24203.1 - 0.00096 19.4 0.1 0.48 10.7 0.0 3.0 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 GAM24203.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 GAM24203.1 - 0.0052 16.4 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 GAM24203.1 - 0.0052 16.1 0.1 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 GAM24203.1 - 0.056 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 GAM24203.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Spermine_synth PF01564.12 GAM24204.1 - 7.4e-06 25.0 0.0 1.1e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 GAM24204.1 - 0.00037 20.0 0.1 0.00052 19.6 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM24204.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Pyr_redox_2 PF07992.9 GAM24205.1 - 6.8e-22 78.3 0.1 9.8e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM24205.1 - 1.6e-11 44.6 2.3 0.0011 19.1 0.1 3.6 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM24205.1 - 3.6e-08 32.6 1.4 0.00032 19.7 0.1 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 GAM24205.1 - 3.3e-07 30.6 0.1 0.0032 17.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM24205.1 - 0.0031 16.4 0.2 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAM24205.1 - 0.0035 17.5 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding CPSase_L_chain PF00289.17 GAM24205.1 - 0.011 15.8 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_8 PF13450.1 GAM24205.1 - 0.019 14.9 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 GAM24205.1 - 0.027 12.6 0.0 0.13 10.4 0.0 1.9 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 GAM24205.1 - 0.046 12.6 0.0 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Malic_M PF03949.10 GAM24205.1 - 0.052 13.0 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_3 PF01494.14 GAM24205.1 - 0.086 11.8 0.9 10 5.0 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain Abhydrolase_5 PF12695.2 GAM24206.1 - 3.3e-08 33.4 0.0 1.1e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM24206.1 - 0.00012 22.0 0.0 0.16 11.8 0.0 2.8 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 GAM24206.1 - 0.0011 18.4 0.0 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM24206.1 - 0.0025 17.0 0.1 0.34 10.0 0.0 2.1 1 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAM24206.1 - 0.086 12.3 0.3 0.44 10.0 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAM24206.1 - 0.15 10.9 0.0 0.59 8.9 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme eIF-3_zeta PF05091.7 GAM24207.1 - 0.048 12.2 6.9 0.06 11.9 4.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CAF-1_p150 PF11600.3 GAM24207.1 - 0.07 12.4 24.8 0.079 12.3 17.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal COPR5 PF15340.1 GAM24207.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.1 1 1 1 2 2 2 0 Cooperator of PRMT5 family DUF1515 PF07439.6 GAM24207.1 - 0.63 9.8 3.2 0.75 9.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF763 PF05559.6 GAM24207.1 - 1.8 7.4 7.3 2.1 7.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Borrelia_P83 PF05262.6 GAM24207.1 - 2.2 6.4 17.5 2.5 6.2 12.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DDHD PF02862.12 GAM24207.1 - 3.8 7.2 10.9 4.1 7.1 7.6 1.1 1 0 0 1 1 1 0 DDHD domain Asp-B-Hydro_N PF05279.6 GAM24207.1 - 3.9 7.2 20.0 5 6.8 13.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Parvo_coat PF00740.13 GAM24207.1 - 4.3 6.1 7.2 4.5 6.1 5.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Glutaredoxin2_C PF04399.8 GAM24208.1 - 0.011 15.2 0.1 0.032 13.8 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Clat_adaptor_s PF01217.15 GAM24209.1 - 4.2e-20 71.9 2.9 5.4e-20 71.5 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.23 GAM24210.1 - 1.1e-71 241.3 0.1 1.3e-71 241.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM24210.1 - 1.8e-10 41.5 0.0 5.5e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 GAM24211.1 - 2.6e-51 174.2 0.1 1.5e-50 171.7 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24211.1 - 3.9e-21 75.2 0.2 4.2e-13 48.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM24211.1 - 0.00011 21.3 0.1 0.037 12.9 0.0 3.0 2 1 0 3 3 3 1 Kinase-like APH PF01636.18 GAM24211.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tricorn_C1 PF14684.1 GAM24211.1 - 0.11 12.3 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease C1 domain ThiG PF05690.9 GAM24211.1 - 0.25 10.3 0.0 0.48 9.4 0.0 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG adh_short PF00106.20 GAM24212.1 - 2e-28 99.3 0.1 2.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM24212.1 - 1.2e-18 67.7 0.0 1.9e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM24212.1 - 2.3e-09 37.1 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 GAM24212.1 - 0.0089 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 GAM24212.1 - 0.032 13.6 0.1 0.065 12.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 GAM24212.1 - 0.05 13.2 0.3 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cytochrom_C1 PF02167.10 GAM24213.1 - 1e-77 260.7 0.0 1.2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 GAM24213.1 - 0.0011 19.0 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 GAM24213.1 - 0.1 13.4 0.6 0.29 12.0 0.3 1.8 2 0 0 2 2 2 0 Cytochrome c UQ_con PF00179.21 GAM24214.1 - 6e-15 54.9 0.0 6.6e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM24214.1 - 0.032 14.1 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ldh_1_C PF02866.13 GAM24215.1 - 2.2e-37 128.4 0.0 3.5e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 GAM24215.1 - 3.6e-30 104.6 0.1 5.6e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain G-alpha PF00503.15 GAM24216.1 - 1.8e-106 356.1 11.3 2.1e-106 355.9 7.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM24216.1 - 5.7e-17 61.5 3.0 5.1e-10 38.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM24216.1 - 1.3e-05 24.4 2.0 0.0025 17.0 0.3 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM24216.1 - 7.1e-05 23.2 0.1 0.72 10.3 0.0 3.1 2 1 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 GAM24216.1 - 0.049 13.1 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_S8 PF00410.14 GAM24217.1 - 4.6e-23 81.4 0.0 5.5e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 BBS2_Mid PF14783.1 GAM24218.1 - 6.5e-06 25.8 0.1 0.69 9.7 0.0 4.4 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 GAM24218.1 - 0.0006 19.4 1.2 1.4 8.5 0.0 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal FNIP PF05725.7 GAM24219.1 - 2.1e-63 210.0 11.6 1.1e-16 60.5 0.5 5.4 5 0 0 5 5 5 5 FNIP Repeat Metallophos_C PF14008.1 GAM24220.1 - 6.4e-18 64.5 0.1 1.9e-17 63.0 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAM24220.1 - 1.7e-13 50.3 1.1 3.1e-13 49.5 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM24220.1 - 2.3e-06 27.5 0.0 1.9e-05 24.5 0.0 2.2 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 GAM24220.1 - 6.5e-05 21.6 0.1 0.00013 20.6 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase MM_CoA_mutase PF01642.17 GAM24221.1 - 0.062 11.4 0.0 0.088 10.9 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase Lipin_N PF04571.9 GAM24221.1 - 0.066 12.8 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 lipin, N-terminal conserved region Rap_GAP PF02145.10 GAM24222.1 - 5.1e-63 211.8 0.4 5.1e-63 211.8 0.3 1.9 2 0 0 2 2 2 1 Rap/ran-GAP AAA_11 PF13086.1 GAM24222.1 - 0.011 15.2 4.7 0.034 13.7 2.7 2.1 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.7 GAM24222.1 - 0.35 9.1 6.4 0.55 8.5 4.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Borrelia_P83 PF05262.6 GAM24222.1 - 1.1 7.4 15.5 1.6 6.8 10.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Daxx PF03344.10 GAM24222.1 - 1.1 7.6 23.7 4.3 5.6 16.4 1.8 1 1 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 GAM24222.1 - 1.3 8.8 16.9 2.6 7.8 11.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 GAM24222.1 - 2 8.7 15.0 0.018 15.3 3.7 2.2 2 1 0 2 2 2 0 AAA domain SR-25 PF10500.4 GAM24222.1 - 2.1 7.7 39.0 0.15 11.4 0.2 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DDHD PF02862.12 GAM24222.1 - 2.4 7.9 18.2 2.9 7.6 7.7 2.3 2 0 0 2 2 2 0 DDHD domain GAGA_bind PF06217.7 GAM24222.1 - 2.9 7.7 10.5 5.6 6.8 7.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Kelch_4 PF13418.1 GAM24223.1 - 1.6e-10 40.5 1.1 0.0013 18.4 0.0 3.8 3 1 1 4 4 4 3 Galactose oxidase, central domain zf-B_box PF00643.19 GAM24223.1 - 2.9e-08 33.4 3.7 2.9e-08 33.4 2.6 2.4 2 0 0 2 2 2 1 B-box zinc finger Kelch_1 PF01344.20 GAM24223.1 - 6.9e-08 31.9 0.0 0.00036 20.0 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 GAM24223.1 - 6.9e-07 29.2 0.0 0.07 13.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24223.1 - 1.1e-05 25.3 0.2 0.62 10.3 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM24223.1 - 3.4e-05 23.4 1.0 0.35 10.7 0.0 4.3 4 0 0 4 4 4 1 Kelch motif DUF3268 PF11672.3 GAM24223.1 - 0.053 13.5 1.5 0.22 11.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Kelch_5 PF13854.1 GAM24223.1 - 0.55 10.2 5.6 19 5.3 0.0 3.8 4 0 0 4 4 4 0 Kelch motif IBR PF01485.16 GAM24223.1 - 9 6.2 9.5 1.1 9.1 2.5 2.6 3 0 0 3 3 3 0 IBR domain Acetyltransf_1 PF00583.19 GAM24224.1 - 3.8e-12 46.0 0.0 5.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM24224.1 - 8.4e-11 41.8 0.1 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM24224.1 - 1.6e-08 34.6 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM24224.1 - 9.2e-06 25.3 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 GAM24224.1 - 0.0005 20.2 0.0 0.0007 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 GAM24224.1 - 0.0023 17.9 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM24224.1 - 0.0042 16.9 0.1 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAM24224.1 - 0.014 14.9 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM24224.1 - 0.041 13.8 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATPase-cat_bd PF12156.3 GAM24225.1 - 0.00035 21.0 0.1 0.00038 20.9 0.1 1.1 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Maelstrom PF13017.1 GAM24225.1 - 0.012 15.1 0.2 0.012 15.1 0.1 1.2 1 0 0 1 1 1 0 piRNA pathway germ-plasm component FNIP PF05725.7 GAM24226.1 - 1.5e-10 40.8 12.1 0.00072 19.4 0.1 5.5 5 1 0 5 5 5 3 FNIP Repeat PPARgamma_N PF12577.3 GAM24226.1 - 0.067 13.5 0.4 5.6 7.3 0.0 2.6 2 1 0 2 2 2 0 PPAR gamma N-terminal region LRR_8 PF13855.1 GAM24226.1 - 0.47 10.2 14.1 2.2 8.1 0.3 5.0 4 2 1 5 5 5 0 Leucine rich repeat RCC1 PF00415.13 GAM24228.1 - 1e-39 134.4 17.6 1.7e-08 34.5 0.0 8.4 9 1 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM24228.1 - 3e-27 93.5 33.1 3.9e-06 26.3 0.1 8.0 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Profilin PF00235.14 GAM24228.1 - 5.4e-08 32.9 0.4 1.9e-07 31.1 0.3 1.9 1 1 0 1 1 1 1 Profilin SUKH-3 PF14433.1 GAM24228.1 - 0.047 13.4 0.2 3.9 7.2 0.0 3.1 2 1 1 3 3 3 0 SUKH-3 immunity protein Reg_prop PF07494.6 GAM24228.1 - 0.065 13.2 0.3 9.5 6.6 0.0 4.1 4 0 0 4 4 4 0 Two component regulator propeller Kelch_4 PF13418.1 GAM24228.1 - 0.11 12.3 7.3 19 5.0 0.1 4.3 4 0 0 4 4 4 0 Galactose oxidase, central domain Flocculin_t3 PF13928.1 GAM24228.1 - 9.4 6.4 8.9 1.9 8.7 0.1 3.1 3 0 0 3 3 3 0 Flocculin type 3 repeat GMC_oxred_N PF00732.14 GAM24229.1 - 8e-41 140.1 0.0 1.6e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM24229.1 - 1e-21 77.7 0.0 2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 GAM24229.1 - 0.049 12.5 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein RabGAP-TBC PF00566.13 GAM24230.1 - 4.5e-44 150.4 5.2 8.8e-44 149.5 3.6 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_20 PF00728.17 GAM24231.1 - 4.9e-82 275.9 1.7 6.1e-82 275.5 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM24231.1 - 1.7e-17 64.2 0.0 3.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM24231.1 - 7.3e-05 23.3 0.0 0.00017 22.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 YtzH PF14165.1 GAM24232.1 - 0.1 12.8 1.7 0.54 10.5 0.1 2.6 3 0 0 3 3 3 0 YtzH-like protein SR-25 PF10500.4 GAM24233.1 - 0.0016 17.9 8.5 0.0026 17.2 5.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BLVR PF06375.6 GAM24233.1 - 0.036 13.9 9.6 0.065 13.0 6.6 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) STAG PF08514.6 GAM24233.1 - 0.15 11.7 2.3 0.25 11.0 1.6 1.2 1 0 0 1 1 1 0 STAG domain Peptidase_S49_N PF08496.5 GAM24233.1 - 0.24 11.1 6.4 0.4 10.4 4.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Conotoxin PF02950.12 GAM24233.1 - 1.7 9.4 3.9 2.3 9.0 0.9 2.3 2 0 0 2 2 2 0 Conotoxin zf-RING_2 PF13639.1 GAM24234.1 - 2.5e-11 43.2 4.5 2.5e-11 43.2 3.1 2.0 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 GAM24234.1 - 1.1e-08 35.0 3.5 4.2e-08 33.1 2.4 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM24234.1 - 1.1e-06 28.6 6.9 4.1e-06 26.7 4.9 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM24234.1 - 4.4e-05 23.0 7.2 0.0002 20.9 5.1 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM24234.1 - 0.0001 21.9 5.0 0.00027 20.5 3.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAM24234.1 - 0.00011 22.0 4.6 0.0003 20.5 3.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 GAM24234.1 - 0.0055 16.6 3.6 0.012 15.5 2.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 GAM24234.1 - 0.015 15.3 2.6 0.039 13.9 1.8 1.7 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 GAM24234.1 - 0.025 14.1 4.7 0.065 12.7 3.3 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAM24234.1 - 0.16 11.6 4.2 0.42 10.3 2.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF3439 PF11921.3 GAM24234.1 - 9 6.0 17.4 0.3 10.8 1.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3439) Nol1_Nop2_Fmu PF01189.12 GAM24235.1 - 3e-92 309.0 0.0 4.4e-92 308.4 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 GAM24235.1 - 1.1e-05 25.4 0.0 0.00022 21.2 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.11 GAM24235.1 - 0.00043 19.9 0.0 0.00099 18.7 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 GAM24235.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 GAM24236.1 - 1.8e-67 227.2 0.0 1.8e-67 227.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24236.1 - 7.6e-47 159.5 0.0 1.5e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM24236.1 - 3e-13 49.9 0.3 3e-13 49.9 0.2 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 GAM24236.1 - 0.0009 18.2 0.0 0.0045 15.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like DUF572 PF04502.8 GAM24236.1 - 1.8 7.7 32.5 2.4 7.3 21.9 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 GAM24236.1 - 5.9 6.1 30.5 3.6 6.8 19.4 1.8 1 1 0 1 1 1 0 Vta1 like Chromo PF00385.19 GAM24237.1 - 1.9e-13 49.8 0.7 1.9e-13 49.8 0.5 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PBP1_TM PF14812.1 GAM24237.1 - 0.0022 18.2 6.0 0.0022 18.2 4.2 4.6 2 1 2 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal ATG_C PF09333.6 GAM24239.1 - 5e-11 42.6 0.0 0.00021 21.3 0.0 2.7 2 0 0 2 2 2 2 ATG C terminal domain zf-B_box PF00643.19 GAM24239.1 - 0.0024 17.7 5.6 0.0046 16.8 3.9 1.4 1 0 0 1 1 1 1 B-box zinc finger SelP_N PF04592.9 GAM24239.1 - 5.3 6.3 20.3 0.054 12.8 7.7 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Lactamase_B_2 PF12706.2 GAM24240.1 - 1.1e-30 106.7 0.4 2.7e-28 98.8 0.6 2.5 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 GAM24240.1 - 4.9e-13 48.3 0.2 4.5e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 GAM24240.1 - 0.013 15.1 0.1 0.032 13.8 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CPG4 PF15481.1 GAM24240.1 - 0.049 13.9 0.9 0.46 10.8 0.1 2.6 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 adh_short PF00106.20 GAM24241.1 - 3e-29 102.0 0.0 4.1e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM24241.1 - 4.9e-25 88.7 0.0 6.2e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM24241.1 - 3e-14 53.0 0.0 4.1e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM24241.1 - 6.4e-05 22.5 0.0 0.00057 19.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 GAM24241.1 - 7e-05 21.9 0.2 0.0023 17.0 0.0 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 GAM24241.1 - 0.0011 18.9 0.0 0.069 13.1 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM24241.1 - 0.0074 16.0 0.2 0.013 15.2 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ATP-synt_C PF00137.16 GAM24242.1 - 0.11 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP synthase subunit C Metallophos_2 PF12850.2 GAM24244.1 - 8.3e-22 77.6 0.2 1e-21 77.4 0.2 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 GAM24244.1 - 3.1e-07 29.9 1.4 0.0015 17.9 0.2 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PH PF00169.24 GAM24245.1 - 2.8e-10 40.3 0.0 7.8e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Z1 PF10593.4 GAM24245.1 - 0.3 10.2 11.1 1.2 8.2 2.0 2.9 2 1 1 3 3 3 0 Z1 domain 2-oxoacid_dh PF00198.18 GAM24246.1 - 2.5e-71 239.6 0.1 3.6e-71 239.1 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 GAM24246.1 - 1.4e-09 37.3 0.0 3.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Mito_carr PF00153.22 GAM24247.1 - 2.5e-70 232.2 1.5 1.1e-25 89.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NIF3 PF01784.13 GAM24248.1 - 1.2e-61 208.3 0.0 1.5e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) NTP_transf_3 PF12804.2 GAM24248.1 - 0.082 12.9 0.0 0.3 11.1 0.0 1.9 1 1 0 1 1 1 0 MobA-like NTP transferase domain CALCOCO1 PF07888.6 GAM24249.1 - 0.0022 16.3 12.8 0.0027 16.0 8.9 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF948 PF06103.6 GAM24249.1 - 0.0027 17.5 1.2 0.0027 17.5 0.8 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 GAM24249.1 - 0.012 15.5 23.5 2 8.3 16.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) NADH_u_ox_C PF12853.2 GAM24249.1 - 0.061 13.0 0.8 0.14 11.8 0.4 1.7 1 1 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF3399 PF11879.3 GAM24249.1 - 0.068 13.3 0.4 0.068 13.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) DUF869 PF05911.6 GAM24249.1 - 0.097 10.8 15.6 0.12 10.6 10.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Transposase_22 PF02994.9 GAM24249.1 - 0.14 10.6 18.7 0.025 13.0 3.9 2.0 1 1 1 2 2 2 0 L1 transposable element DUF2229 PF09989.4 GAM24249.1 - 0.33 10.3 4.2 0.4 10.1 2.9 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DHC PF09626.5 GAM24249.1 - 0.36 11.5 3.7 0.84 10.3 0.3 2.1 1 1 1 2 2 2 0 Dihaem cytochrome c ATP-synt_E PF05680.7 GAM24249.1 - 1.5 8.8 6.7 3.9 7.5 4.7 1.8 1 1 0 1 1 1 0 ATP synthase E chain TLE_N PF03920.10 GAM24249.1 - 5.9 6.7 11.9 1.3 8.8 2.4 2.5 1 1 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Atg14 PF10186.4 GAM24249.1 - 6.4 5.6 11.7 8.6 5.1 8.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PEPCK_ATP PF01293.15 GAM24250.1 - 8.1e-43 146.6 0.1 3.4e-25 88.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase Ank_2 PF12796.2 GAM24252.1 - 4e-06 27.0 1.1 0.11 12.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24252.1 - 0.003 17.6 2.7 8.7 6.9 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 GAM24252.1 - 0.014 15.5 1.3 14 6.1 0.0 5.0 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM24252.1 - 0.028 14.2 1.6 12 5.8 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.1 GAM24252.1 - 0.056 13.9 2.4 6.2 7.4 0.0 4.5 3 2 0 3 3 3 0 Ankyrin repeats (many copies) Tricorn_C1 PF14684.1 GAM24252.1 - 0.058 13.2 1.5 0.15 11.9 1.1 1.7 1 0 0 1 1 1 0 Tricorn protease C1 domain BNR PF02012.15 GAM24253.1 - 1.4e-13 48.4 44.5 0.48 10.4 0.1 9.9 9 0 0 9 9 9 9 BNR/Asp-box repeat BNR_2 PF13088.1 GAM24253.1 - 1.4e-13 50.7 9.9 2.9e-07 30.0 0.5 5.3 3 1 1 4 4 4 4 BNR repeat-like domain PSII_BNR PF14870.1 GAM24253.1 - 1.5e-07 30.7 16.2 0.047 12.6 0.8 6.3 2 2 3 5 5 5 3 Photosynthesis system II assembly factor YCF48 BNR_3 PF13859.1 GAM24253.1 - 0.28 10.2 14.4 14 4.6 0.0 6.1 5 1 1 6 6 6 0 BNR repeat-like domain DivIC PF04977.10 GAM24254.1 - 0.65 9.5 8.4 1.4 8.4 5.9 1.5 1 0 0 1 1 1 0 Septum formation initiator UQ_con PF00179.21 GAM24255.1 - 6.7e-42 142.2 0.0 7.6e-42 142.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM24255.1 - 2e-05 24.3 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Ras PF00071.17 GAM24256.1 - 9.1e-57 190.9 0.0 1.1e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24256.1 - 1.2e-16 61.2 0.0 2.7e-16 60.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM24256.1 - 0.00012 21.3 0.0 0.0003 20.0 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM24256.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region RGS PF00615.14 GAM24257.1 - 1.3e-16 60.7 5.0 2.3e-12 47.0 0.4 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain Sec3_C PF09763.4 GAM24258.1 - 9.1e-148 493.4 20.4 1.1e-147 493.1 14.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 CCDC-167 PF15188.1 GAM24258.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1033 PF06279.6 GAM24258.1 - 0.089 12.6 9.7 1.4 8.7 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) Ank PF00023.25 GAM24259.1 - 1.7e-39 131.6 9.3 4.7e-11 41.9 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 GAM24259.1 - 1.6e-37 127.6 12.4 2.1e-18 66.4 1.8 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM24259.1 - 2.2e-35 120.3 8.5 3.1e-13 49.8 0.1 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM24259.1 - 3.2e-29 100.2 5.7 5.3e-11 42.3 1.1 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Bromodomain PF00439.20 GAM24259.1 - 6.9e-24 83.5 2.8 1.6e-23 82.4 1.9 1.6 1 0 0 1 1 1 1 Bromodomain Ank_3 PF13606.1 GAM24259.1 - 1.4e-21 74.4 5.0 2e-06 27.4 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat BTB PF00651.26 GAM24259.1 - 4.5e-20 71.6 0.1 4.5e-20 71.6 0.1 2.9 4 0 0 4 4 4 1 BTB/POZ domain DUF2179 PF10035.4 GAM24259.1 - 0.046 13.3 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) Ras PF00071.17 GAM24261.1 - 4e-53 179.1 0.0 2.3e-52 176.6 0.0 2.2 2 0 0 2 2 2 1 Ras family BTB PF00651.26 GAM24261.1 - 2.6e-34 117.5 5.1 1.3e-18 66.9 0.1 3.4 3 0 0 3 3 3 3 BTB/POZ domain Miro PF08477.8 GAM24261.1 - 4.3e-14 53.0 0.0 1.3e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24261.1 - 3.9e-05 22.9 0.0 0.00019 20.7 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM24261.1 - 0.00039 19.9 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain BACK PF07707.10 GAM24261.1 - 0.001 18.8 0.9 0.021 14.6 0.1 3.0 3 0 0 3 3 3 1 BTB And C-terminal Kelch MMR_HSR1 PF01926.18 GAM24261.1 - 0.059 13.3 0.0 0.23 11.4 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase Translin PF01997.11 GAM24262.1 - 5.9e-56 189.2 7.9 6.7e-56 189.0 5.4 1.0 1 0 0 1 1 1 1 Translin family LktC PF06261.6 GAM24262.1 - 0.00024 20.8 0.4 0.00024 20.8 0.3 2.0 2 2 1 3 3 3 1 Actinobacillus actinomycetemcomitans leukotoxin activator LktC CDC37_N PF03234.9 GAM24262.1 - 0.0016 18.7 2.5 0.33 11.2 1.2 2.0 2 0 0 2 2 2 2 Cdc37 N terminal kinase binding Galactosyl_T PF01762.16 GAM24262.1 - 0.0024 17.4 1.7 0.0039 16.7 1.1 1.5 1 1 0 1 1 1 1 Galactosyltransferase Rad17 PF03215.10 GAM24263.1 - 9.4e-54 182.9 9.5 1.7e-53 182.1 6.6 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein T2SE PF00437.15 GAM24263.1 - 0.00099 18.0 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 GAM24263.1 - 0.0027 16.9 0.1 0.017 14.3 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 GAM24263.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 GAM24263.1 - 0.016 15.3 0.1 0.075 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM24263.1 - 0.037 13.6 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 GAM24263.1 - 0.041 14.0 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 GAM24263.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Chalcone PF02431.10 GAM24264.1 - 1.4e-26 93.1 0.3 1.9e-26 92.6 0.2 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Ras PF00071.17 GAM24265.1 - 4.4e-31 107.4 0.0 5.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24265.1 - 1.1e-16 61.4 0.0 1.8e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24265.1 - 4.6e-13 48.7 0.0 6.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM24265.1 - 1.2e-06 27.8 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM24265.1 - 2.3e-05 24.2 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 GAM24265.1 - 0.0041 17.0 0.1 0.013 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 GAM24265.1 - 0.0054 16.1 0.0 0.021 14.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MobB PF03205.9 GAM24265.1 - 0.0087 15.7 0.3 0.016 14.9 0.2 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 GAM24265.1 - 0.011 16.5 0.0 0.018 15.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 GAM24265.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAM24265.1 - 0.023 13.9 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 GAM24265.1 - 0.024 14.7 0.1 0.042 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAM24265.1 - 0.03 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 GAM24265.1 - 0.047 13.3 0.1 0.073 12.7 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase Zot PF05707.7 GAM24265.1 - 0.087 12.2 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA PF00004.24 GAM24265.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAM24265.1 - 0.14 12.0 0.3 0.39 10.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain EGF_2 PF07974.8 GAM24266.1 - 3.9e-07 30.1 30.8 0.0012 18.9 6.6 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 GAM24266.1 - 0.00038 20.3 25.1 0.047 13.6 4.7 2.6 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 GAM24266.1 - 0.002 18.0 10.8 0.23 11.6 0.2 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 GAM24266.1 - 1.9 8.4 20.9 4.4 7.3 7.1 2.4 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) cEGF PF12662.2 GAM24266.1 - 7.4 6.3 9.6 16 5.2 2.1 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like Asn_synthase PF00733.16 GAM24267.1 - 2.2e-30 106.0 0.0 3.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Ras PF00071.17 GAM24268.1 - 1.8e-55 186.7 0.0 2.1e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24268.1 - 1.9e-17 63.8 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24268.1 - 1.3e-09 37.4 0.0 1.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM24268.1 - 3.1e-05 23.4 0.0 0.00027 20.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM24268.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPR_11 PF13414.1 GAM24269.1 - 1.2e-07 31.2 1.1 4.1e-05 23.1 0.1 3.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM24269.1 - 1.7e-05 24.2 3.3 8.6e-05 21.9 0.0 3.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24269.1 - 4.4e-05 23.0 0.6 0.00092 18.9 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24269.1 - 0.0001 22.5 0.3 0.0016 18.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24269.1 - 0.00022 21.1 1.9 1.2 9.5 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24269.1 - 0.0004 20.9 0.0 0.0035 17.9 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24269.1 - 0.00068 19.2 0.4 0.0067 16.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24269.1 - 0.002 18.0 0.7 0.019 14.9 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM24269.1 - 0.0032 17.2 0.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24269.1 - 0.0094 16.5 0.0 0.032 14.8 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM24269.1 - 0.031 14.3 3.5 0.059 13.5 0.4 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 GAM24269.1 - 0.051 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FNIP PF05725.7 GAM24270.1 - 9.3e-62 204.7 22.3 1.1e-14 54.0 0.1 7.1 4 1 2 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 GAM24270.1 - 0.00087 19.1 1.2 10 6.1 0.0 5.6 4 1 2 6 6 6 1 Protein of unknown function (DUF1769) DUF167 PF02594.11 GAM24271.1 - 2.5e-22 78.6 0.5 3.2e-22 78.2 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HSDR_N_2 PF13588.1 GAM24271.1 - 0.051 13.3 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) WD40 PF00400.27 GAM24272.1 - 2e-16 59.1 8.8 0.00027 20.7 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat DNA_ligase_aden PF01653.13 GAM24272.1 - 0.038 12.9 0.1 0.059 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain NTF2 PF02136.15 GAM24273.1 - 1e-18 67.8 0.2 2.8e-18 66.3 0.2 1.8 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 GAM24273.1 - 9.4e-07 28.3 0.1 1.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM24273.1 - 0.0026 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM24273.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ssl1 PF04056.9 GAM24274.1 - 4.1e-70 235.2 0.7 5.6e-70 234.8 0.5 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 GAM24274.1 - 1.8e-14 53.4 11.7 1.8e-14 53.4 8.1 2.8 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 GAM24274.1 - 8.1e-07 29.2 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.11 GAM24274.1 - 8 6.2 29.0 2.3 7.9 3.6 3.8 3 1 0 3 3 3 0 HIT zinc finger IBR PF01485.16 GAM24274.1 - 9.2 6.2 27.0 5 7.0 7.8 3.5 2 1 1 3 3 3 0 IBR domain SRR1 PF07985.7 GAM24275.1 - 6.6e-17 61.1 0.1 9.9e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 SRR1 PG_binding_1 PF01471.13 GAM24277.1 - 1.7e-10 40.7 0.1 3.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Mon1 PF03164.9 GAM24277.1 - 0.00013 20.7 2.7 0.00013 20.7 1.9 2.1 2 0 0 2 2 2 1 Trafficking protein Mon1 Lon_C PF05362.8 GAM24278.1 - 2e-67 226.4 0.0 3.6e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 GAM24278.1 - 2.6e-23 82.6 0.0 6.8e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 GAM24278.1 - 6.7e-07 29.1 0.0 2.7e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 GAM24278.1 - 2e-06 27.5 0.0 4.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 GAM24278.1 - 4.5e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 GAM24278.1 - 7.8e-06 25.4 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 GAM24278.1 - 7.8e-05 23.4 0.0 0.00038 21.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_PrkA PF08298.6 GAM24278.1 - 0.00026 19.8 0.0 0.00058 18.6 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 GAM24278.1 - 0.00032 20.8 1.3 0.014 15.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM24278.1 - 0.00058 19.9 0.2 0.0057 16.6 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 GAM24278.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 GAM24278.1 - 0.0064 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAM24278.1 - 0.0083 16.0 0.4 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM24278.1 - 0.0086 14.8 0.6 0.12 11.0 0.0 2.5 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 GAM24278.1 - 0.01 14.8 0.0 0.046 12.7 0.0 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 GAM24278.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 GAM24278.1 - 0.013 15.2 0.4 1.3 8.6 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_3 PF07726.6 GAM24278.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM24278.1 - 0.021 14.2 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 GAM24278.1 - 0.031 14.0 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 GAM24278.1 - 0.041 14.1 1.8 0.3 11.3 0.0 2.7 2 1 0 2 2 2 0 ABC transporter ATP-synt_ab PF00006.20 GAM24278.1 - 0.05 13.1 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 GAM24278.1 - 0.057 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 GAM24278.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM24278.1 - 1.5 9.0 15.0 0.11 12.8 0.2 3.0 3 1 0 3 3 3 0 AAA domain DUF1751 PF08551.5 GAM24279.1 - 3.6e-23 81.7 5.2 8.7e-23 80.5 3.6 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 GAM24279.1 - 2.3e-06 27.7 11.9 2.3e-06 27.7 8.3 1.5 2 0 0 2 2 2 1 Rhomboid family Med3 PF11593.3 GAM24279.1 - 0.49 9.5 7.3 0.62 9.2 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Arf PF00025.16 GAM24281.1 - 1.1e-29 102.8 0.0 1.4e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM24281.1 - 7.3e-08 32.9 0.1 1e-07 32.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM24281.1 - 2.8e-06 26.6 0.9 5.5e-06 25.7 0.6 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM24281.1 - 6.6e-06 26.0 2.3 0.00034 20.5 1.5 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 GAM24281.1 - 2.6e-05 23.6 0.0 5.7e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Ras family cobW PF02492.14 GAM24281.1 - 0.00017 21.0 0.3 0.46 9.9 0.1 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 GAM24281.1 - 0.00025 19.8 0.6 0.078 11.6 0.1 2.1 2 0 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 GAM24281.1 - 0.00093 18.6 0.1 1 8.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 GAM24281.1 - 0.0014 18.3 0.1 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAM24281.1 - 0.0032 17.2 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 GAM24281.1 - 0.013 15.3 0.1 0.023 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM24281.1 - 0.041 14.6 0.0 0.066 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM24281.1 - 0.044 13.9 0.2 0.17 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 GAM24281.1 - 0.051 12.8 1.7 0.44 9.8 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Arv1 PF04161.8 GAM24282.1 - 2.8e-48 164.5 8.0 3.8e-48 164.1 5.6 1.2 1 0 0 1 1 1 1 Arv1-like family Ribosomal_L3 PF00297.17 GAM24283.1 - 3.9e-37 128.0 4.6 9.6e-36 123.5 3.2 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 MFS_1 PF07690.11 GAM24284.1 - 1.4e-43 148.9 60.9 2e-35 122.1 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PepSY_TM_1 PF13172.1 GAM24284.1 - 0.046 13.4 0.5 0.046 13.4 0.4 3.7 3 0 0 3 3 3 0 PepSY-associated TM helix Spore_YhcN_YlaJ PF09580.5 GAM24285.1 - 3.8 7.5 8.2 5.6 7.0 5.7 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Pex14_N PF04695.8 GAM24285.1 - 6 6.9 17.6 5.3 7.0 0.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Na_H_Exchanger PF00999.16 GAM24286.1 - 2.2e-53 181.1 36.0 4.8e-29 101.0 10.1 2.1 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.7 GAM24286.1 - 2e-05 24.1 7.1 2e-05 24.1 4.9 2.2 2 1 1 3 3 3 1 Predicted Permease Membrane Region Tweety PF04906.8 GAM24287.1 - 7.2e-13 47.7 5.1 1.5e-08 33.4 0.8 2.1 1 1 1 2 2 2 2 Tweety Claudin_2 PF13903.1 GAM24287.1 - 0.00048 19.8 1.4 0.0025 17.5 0.3 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 GAM24287.1 - 0.00087 18.7 0.7 0.039 13.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) Amastin PF07344.6 GAM24287.1 - 0.0026 17.3 5.6 0.024 14.2 0.3 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein ABC2_membrane_4 PF12730.2 GAM24287.1 - 0.02 14.0 0.4 0.02 14.0 0.3 2.5 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF462 PF04315.7 GAM24287.1 - 0.035 13.4 0.1 0.091 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF462 O-antigen_lig PF13425.1 GAM24287.1 - 0.073 13.0 4.7 1.2 9.0 0.8 2.3 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Ribosomal_L14 PF00238.14 GAM24288.1 - 1.2e-29 102.5 0.0 1.3e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e EF-hand_7 PF13499.1 GAM24289.1 - 4.9e-10 39.3 0.0 6.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM24289.1 - 4.6e-09 34.9 0.0 0.00058 18.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 GAM24289.1 - 2.3e-08 33.5 0.1 0.0003 20.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM24289.1 - 6.8e-08 31.7 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM24289.1 - 1.6e-07 30.3 0.0 2.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 GAM24289.1 - 0.11 12.2 0.3 0.98 9.1 0.2 2.0 1 1 1 2 2 2 0 EF hand Sulf_transp PF04143.9 GAM24290.1 - 8.7e-17 60.8 22.2 2.8e-08 33.6 3.7 3.4 2 1 0 2 2 2 2 Sulphur transport DUF4341 PF14241.1 GAM24290.1 - 0.00083 18.9 0.6 0.00083 18.9 0.4 4.1 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) DUF1980 PF09323.5 GAM24291.1 - 0.0028 17.4 1.1 0.0029 17.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Y_Y_Y PF07495.8 GAM24293.1 - 0.002 17.8 14.3 0.035 13.8 0.4 4.4 4 0 0 4 4 4 2 Y_Y_Y domain CarboxypepD_reg PF13620.1 GAM24293.1 - 0.017 15.1 3.7 3.3 7.8 0.0 3.7 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain RNA_helicase PF00910.17 GAM24294.1 - 0.00051 20.1 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase RHSP PF07999.6 GAM24294.1 - 0.0012 17.5 0.0 0.029 12.9 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon hot spot protein SHOCT PF09851.4 GAM24294.1 - 0.0058 16.0 0.9 0.01 15.2 0.6 1.4 1 0 0 1 1 1 1 Short C-terminal domain AAA_16 PF13191.1 GAM24294.1 - 0.014 15.4 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 GAM24294.1 - 0.023 15.1 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 GAM24294.1 - 0.073 12.7 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.1 GAM24294.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DPBB_1 PF03330.13 GAM24295.1 - 1e-06 28.6 0.3 3.1e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel PHD PF00628.24 GAM24296.1 - 4.9e-05 22.9 21.9 9.7e-05 21.9 4.0 3.0 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 GAM24296.1 - 0.007 16.0 2.9 0.007 16.0 2.0 2.5 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 GAM24296.1 - 0.015 14.5 11.4 0.066 12.4 1.5 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 GAM24296.1 - 0.17 11.2 15.5 0.2 11.0 8.0 2.7 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 GAM24296.1 - 0.54 10.0 20.1 1.8 8.3 9.9 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Herpes_LAMP2 PF06126.6 GAM24297.1 - 3.5 5.9 4.9 6.1 5.1 3.4 1.3 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 CH PF00307.26 GAM24298.1 - 1.2e-67 224.7 0.1 3.5e-17 62.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.27 GAM24298.1 - 2.6e-13 48.2 6.2 1.5e-07 30.2 0.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAM24298.1 - 1.3e-11 44.4 3.1 1.3e-11 44.4 0.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM24298.1 - 1.8e-11 42.9 2.5 7e-06 25.5 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 GAM24298.1 - 2.5e-11 42.9 2.9 8.8e-11 41.2 1.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM24298.1 - 2.8e-10 39.0 5.2 3.2e-05 23.0 0.7 2.9 2 0 0 2 2 2 2 EF hand CAMSAP_CH PF11971.3 GAM24298.1 - 1.1e-06 28.2 0.0 0.81 9.3 0.0 4.2 4 0 0 4 4 4 2 CAMSAP CH domain SPARC_Ca_bdg PF10591.4 GAM24298.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAM24298.1 - 0.12 12.1 0.4 0.29 10.8 0.3 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Senescence PF06911.7 GAM24299.1 - 0.0014 18.3 0.1 0.0014 18.3 0.1 1.1 1 0 0 1 1 1 1 Senescence-associated protein HiaBD2 PF15403.1 GAM24300.1 - 0.001 19.1 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Coiled PF05710.7 GAM24300.1 - 0.032 14.6 3.9 0.038 14.4 2.7 1.1 1 0 0 1 1 1 0 Coiled coil TIG PF01833.19 GAM24304.1 - 0.0018 18.2 6.4 0.0018 18.2 4.5 5.0 2 2 1 3 3 3 2 IPT/TIG domain TPR_19 PF14559.1 GAM24305.1 - 0.09 13.1 0.1 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_10 PF00852.14 GAM24306.1 - 2.6e-47 161.1 1.7 2.3e-46 157.9 0.2 2.2 1 1 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) Laminin_G_3 PF13385.1 GAM24306.1 - 2e-19 70.3 0.1 4.7e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.11 GAM24306.1 - 0.0029 16.6 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Sialidase, N-terminal domain Snf7 PF03357.16 GAM24307.1 - 7e-20 71.1 17.9 9e-20 70.7 12.4 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 GAM24307.1 - 0.00042 19.7 6.5 0.00063 19.1 4.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Nop16 PF09420.5 GAM24307.1 - 0.095 12.8 3.9 0.11 12.5 2.7 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Peptidase_C47 PF05543.8 GAM24307.1 - 0.27 10.6 2.2 0.7 9.2 0.2 2.0 1 1 1 2 2 2 0 Staphopain peptidase C47 DUF4108 PF13390.1 GAM24307.1 - 0.36 10.5 2.7 1.1 9.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4108) YlqD PF11068.3 GAM24307.1 - 3.9 7.5 17.2 3.9 7.5 0.8 2.7 1 1 1 2 2 2 0 YlqD protein Fib_alpha PF08702.5 GAM24307.1 - 9.2 6.3 14.4 0.4 10.8 1.4 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Hema_HEFG PF02710.9 GAM24308.1 - 0.012 15.8 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein DUF836 PF05768.9 GAM24308.1 - 0.028 14.6 0.7 0.032 14.4 0.5 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TPR_11 PF13414.1 GAM24309.1 - 3.1e-26 90.7 20.9 8.5e-09 34.9 1.6 4.6 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM24309.1 - 4.9e-20 70.2 3.3 0.0014 18.1 0.1 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24309.1 - 4.2e-19 66.8 2.5 5.9e-05 22.6 0.0 5.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24309.1 - 1.6e-15 55.9 12.6 0.00019 21.3 0.3 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24309.1 - 4e-14 51.8 5.1 0.016 15.7 0.0 6.5 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_20 PF14561.1 GAM24309.1 - 1.6e-13 50.5 2.9 0.005 16.9 0.0 5.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24309.1 - 9.9e-13 48.3 0.1 1.7e-06 28.5 0.1 4.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24309.1 - 8.7e-11 42.0 5.3 0.00089 19.5 0.2 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24309.1 - 3.6e-08 32.6 2.5 3.1 7.8 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24309.1 - 5.3e-08 32.6 7.9 0.0017 18.2 0.9 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24309.1 - 2.7e-06 26.7 1.3 1.5 8.7 0.3 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM24309.1 - 1.5e-05 24.7 0.2 0.061 13.1 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM24309.1 - 4.3e-05 23.6 2.9 8.4 7.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM24309.1 - 8.6e-05 22.6 3.0 0.1 12.7 1.2 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 GAM24309.1 - 0.045 14.0 3.3 0.11 12.8 0.1 2.9 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_11 PF13414.1 GAM24310.1 - 1.7e-49 165.2 43.5 1.2e-07 31.2 0.4 16.0 10 3 6 17 17 16 12 TPR repeat TPR_16 PF13432.1 GAM24310.1 - 6.5e-40 134.9 17.0 5.5e-05 23.7 0.0 13.1 13 2 1 15 15 14 7 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24310.1 - 3.8e-38 126.3 36.2 0.026 14.3 0.4 19.7 20 0 0 20 20 20 11 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24310.1 - 1.2e-37 124.8 8.4 0.038 14.6 0.0 19.6 14 6 7 21 21 21 7 Tetratricopeptide repeat TPR_1 PF00515.23 GAM24310.1 - 4.7e-28 95.6 37.2 0.0086 15.6 0.5 17.4 19 0 0 19 19 18 8 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24310.1 - 3.6e-26 91.3 40.3 3.3e-05 24.1 0.0 15.9 14 3 5 19 19 17 7 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24310.1 - 8.8e-26 89.6 48.9 0.00048 20.0 0.4 14.3 11 4 5 16 16 16 7 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24310.1 - 3e-22 76.6 32.2 0.016 14.9 0.2 16.4 17 1 1 18 18 17 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24310.1 - 6.6e-19 66.4 25.7 0.024 14.8 0.0 14.0 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24310.1 - 2.1e-15 55.1 24.2 0.27 11.1 0.0 14.4 18 0 0 18 18 18 4 Tetratricopeptide repeat TPR_6 PF13174.1 GAM24310.1 - 8.3e-15 54.1 34.6 0.19 12.2 0.0 16.3 18 0 0 18 18 15 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM24310.1 - 3e-11 43.2 46.5 0.017 15.2 0.1 11.3 11 1 1 12 12 11 6 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.1 GAM24310.1 - 0.023 14.6 0.2 5.7 6.9 0.1 3.5 3 0 0 3 3 2 0 PPR repeat family PPR PF01535.15 GAM24310.1 - 0.028 14.3 0.0 11 6.2 0.0 4.4 4 0 0 4 4 3 0 PPR repeat PPR_1 PF12854.2 GAM24310.1 - 0.09 12.2 0.0 0.34 10.4 0.0 2.1 1 0 0 1 1 1 0 PPR repeat DUF4042 PF13251.1 GAM24311.1 - 3.5e-35 121.1 10.7 1.2e-34 119.3 1.0 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF4042) HEAT PF02985.17 GAM24311.1 - 2.2e-21 73.9 5.2 0.0066 16.4 0.1 9.4 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 GAM24311.1 - 4.3e-15 55.7 0.0 1.1e-07 32.0 0.0 6.0 4 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 GAM24311.1 - 1e-13 51.3 0.4 0.22 12.0 0.0 9.2 10 0 0 10 10 10 3 HEAT-like repeat Arm PF00514.18 GAM24311.1 - 5.3e-05 22.8 10.1 1.1 9.2 0.0 7.5 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 GAM24311.1 - 0.0016 18.3 2.3 1.2 9.1 0.1 4.7 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation LRR_8 PF13855.1 GAM24313.1 - 1.9e-18 65.9 51.2 5.1e-07 29.3 3.3 7.4 4 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 GAM24313.1 - 1.8e-14 52.9 65.8 2.7e-05 23.6 3.5 10.8 5 4 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM24313.1 - 7.1e-11 40.5 54.9 0.0073 16.1 0.8 15.7 16 1 0 16 16 16 3 Leucine Rich Repeat TRP PF06011.7 GAM24313.1 - 0.001 17.7 27.1 0.001 17.7 18.8 2.3 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel LRRNT_2 PF08263.7 GAM24313.1 - 0.016 15.1 0.7 0.043 13.7 0.5 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 GAM24313.1 - 1.4 9.3 29.9 1.7 9.1 0.2 10.6 11 0 0 11 11 11 0 Leucine rich repeat Actin PF00022.14 GAM24314.1 - 2.1e-118 395.2 0.0 2.4e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Actin DUF1702 PF08012.6 GAM24314.1 - 0.045 12.3 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Arf PF00025.16 GAM24315.1 - 4.2e-60 201.9 0.0 4.8e-60 201.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAM24315.1 - 4.5e-12 45.3 0.2 2.7e-09 36.2 0.0 2.4 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 GAM24315.1 - 6.2e-10 38.5 0.0 7.8e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM24315.1 - 1.4e-08 34.3 0.0 1.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24315.1 - 2.5e-07 31.1 0.0 3.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM24315.1 - 5.3e-06 25.7 0.0 5.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM24315.1 - 7e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 GAM24315.1 - 0.04 13.4 0.0 0.17 11.3 0.0 2.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 GAM24315.1 - 0.04 13.3 0.0 1.8 7.9 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Metallophos PF00149.23 GAM24316.1 - 3.4e-43 147.3 0.1 4.5e-43 146.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA_22 PF13401.1 GAM24317.1 - 0.0058 16.7 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM24317.1 - 0.13 12.2 0.1 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain CLU PF13236.1 GAM24318.1 - 4.7e-48 163.5 0.0 9.3e-48 162.5 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM24318.1 - 9.8e-10 38.6 1.2 3.3e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.1 GAM24318.1 - 3.9e-09 36.0 1.3 0.00049 19.6 0.0 2.9 2 1 1 3 3 3 3 TPR repeat TPR_17 PF13431.1 GAM24318.1 - 1.9e-07 30.7 0.7 0.02 15.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24318.1 - 2e-05 24.4 0.6 0.17 11.8 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24318.1 - 0.0024 18.4 0.5 0.034 14.8 0.1 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24318.1 - 0.0026 18.2 0.0 0.68 10.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM24318.1 - 0.0077 15.7 5.3 0.15 11.7 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24318.1 - 0.013 15.3 5.0 0.23 11.4 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24318.1 - 0.02 14.6 0.5 0.09 12.6 0.0 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24318.1 - 0.3 10.9 2.9 0.64 9.9 0.1 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Cyclin_N PF00134.18 GAM24319.1 - 0.013 15.0 0.4 0.024 14.2 0.3 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain RF-1 PF00472.15 GAM24320.1 - 6.6e-17 61.3 0.1 8.2e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 RF-1 domain Evr1_Alr PF04777.8 GAM24323.1 - 2.5e-29 101.0 2.2 5.3e-29 99.9 1.5 1.5 1 0 0 1 1 1 1 Erv1 / Alr family DUF506 PF04720.7 GAM24323.1 - 0.011 15.3 0.7 0.32 10.5 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF506) TM2 PF05154.11 GAM24324.1 - 5.8e-21 74.4 10.4 8.1e-21 73.9 7.2 1.2 1 0 0 1 1 1 1 TM2 domain AAA_33 PF13671.1 GAM24325.1 - 2.3e-11 43.7 0.0 5.5e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM24325.1 - 0.0005 20.0 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM24325.1 - 0.0018 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 GAM24325.1 - 0.0086 15.1 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Adeno_IVa2 PF02456.10 GAM24325.1 - 0.023 13.3 0.0 0.15 10.6 0.0 2.0 1 1 1 2 2 2 0 Adenovirus IVa2 protein AAA_PrkA PF08298.6 GAM24325.1 - 0.043 12.5 0.0 0.072 11.7 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain DUF4190 PF13828.1 GAM24326.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Thr_synth_N PF14821.1 GAM24326.1 - 0.038 14.0 0.2 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Threonine synthase N terminus BCAS3 PF12490.3 GAM24327.1 - 2.2e-10 40.3 1.1 2.2e-10 40.3 0.8 3.0 2 1 0 2 2 2 1 Breast carcinoma amplified sequence 3 DUF4374 PF14298.1 GAM24329.1 - 0.083 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4374) Dicty_spore_N PF04562.7 GAM24330.1 - 1.5e-05 25.2 20.3 2.9e-05 24.3 14.1 1.5 1 0 0 1 1 1 1 Dictyostelium spore coat protein, N terminus PHD PF00628.24 GAM24331.1 - 4.3e-15 55.1 27.6 8.7e-09 34.9 2.6 4.3 3 1 1 4 4 4 2 PHD-finger C1_1 PF00130.17 GAM24331.1 - 0.004 16.8 3.0 0.004 16.8 2.1 5.2 3 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF501 PF04417.7 GAM24331.1 - 0.0075 16.1 3.3 0.02 14.7 2.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF501) MMPL PF03176.10 GAM24331.1 - 0.1 11.2 5.0 0.16 10.6 3.5 1.2 1 0 0 1 1 1 0 MMPL family HutD PF05962.6 GAM24331.1 - 6 6.5 11.6 13 5.4 8.0 1.5 1 0 0 1 1 1 0 HutD DUF342 PF03961.8 GAM24331.1 - 8.1 4.7 13.7 15 3.8 8.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Indigoidine_A PF04227.7 GAM24333.1 - 8.9e-123 409.1 5.3 1.8e-122 408.2 3.7 1.5 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 GAM24333.1 - 7.3e-33 113.9 0.2 1.1e-32 113.3 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Pox_MCEL PF03291.11 GAM24334.1 - 3.8e-70 236.3 0.2 3.8e-70 236.3 0.1 2.1 2 1 0 2 2 2 1 mRNA capping enzyme Methyltransf_11 PF08241.7 GAM24334.1 - 0.00028 21.2 0.0 0.00064 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM24334.1 - 0.0045 16.1 0.0 0.0081 15.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 GAM24334.1 - 0.011 16.2 0.0 0.011 16.2 0.0 3.2 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAM24334.1 - 0.02 15.4 0.0 0.087 13.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 GAM24334.1 - 0.031 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Pkinase PF00069.20 GAM24335.1 - 2.6e-64 216.8 0.2 2.6e-64 216.8 0.1 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24335.1 - 3e-39 134.6 0.0 5.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24335.1 - 1e-09 37.8 0.0 1.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM24335.1 - 0.005 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM24335.1 - 0.0056 16.0 0.9 0.0056 16.0 0.6 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 GAM24335.1 - 0.0074 16.0 0.0 0.2 11.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family COQ7 PF03232.8 GAM24336.1 - 4e-73 244.5 0.1 6.2e-73 243.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 GAM24336.1 - 1.7e-05 25.1 0.9 8.5e-05 22.8 0.5 2.0 1 1 1 2 2 2 1 Rubrerythrin Avl9 PF09794.4 GAM24336.1 - 0.0011 17.5 0.7 0.0019 16.7 0.5 1.3 1 0 0 1 1 1 1 Transport protein Avl9 NTP_transferase PF00483.18 GAM24336.1 - 0.022 14.0 0.1 0.022 14.0 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyl transferase TIG PF01833.19 GAM24337.1 - 4.8e-21 74.5 74.0 3.4e-07 30.1 5.0 8.0 9 1 0 9 9 9 5 IPT/TIG domain Lectin_C PF00059.16 GAM24337.1 - 2.4e-07 31.3 0.0 7.7e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.8 GAM24337.1 - 0.00099 19.2 10.5 0.0029 17.7 7.3 1.8 1 0 0 1 1 1 1 EGF-like domain DUF872 PF05915.7 GAM24337.1 - 0.0051 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF1049 PF06305.6 GAM24337.1 - 0.048 13.1 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) MSC PF09402.5 GAM24337.1 - 5.8 5.5 8.8 0.36 9.5 0.2 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Glycos_transf_2 PF00535.21 GAM24338.1 - 7.2e-37 126.6 0.0 8.8e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM24338.1 - 4.4e-12 46.2 0.0 6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 GAM24338.1 - 7.4e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 GAM24338.1 - 1.5e-05 24.3 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 adh_short PF00106.20 GAM24339.1 - 3.6e-29 101.8 1.1 4.6e-29 101.4 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM24339.1 - 1.3e-16 61.0 0.0 1.9e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM24339.1 - 2.5e-12 46.8 0.3 3.7e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM24339.1 - 5.1e-05 22.8 0.1 0.00014 21.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 GAM24339.1 - 0.00051 19.0 0.1 0.00078 18.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 GAM24339.1 - 0.018 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 GAM24339.1 - 0.019 14.9 0.5 0.045 13.7 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding F-box PF00646.28 GAM24340.1 - 9.6e-07 28.3 0.1 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM24340.1 - 0.021 14.5 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 F-box-like Pyr_redox_2 PF07992.9 GAM24342.1 - 1e-24 87.5 0.2 8.7e-16 58.3 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 GAM24342.1 - 1.6e-09 36.3 1.0 0.00079 18.5 0.2 2.7 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.22 GAM24342.1 - 2.2e-08 34.3 0.0 1.5e-07 31.6 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 GAM24342.1 - 3.8e-07 30.1 2.7 4.6e-07 29.8 0.6 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM24342.1 - 6.9e-07 28.3 4.9 0.0012 18.0 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAM24342.1 - 8.7e-07 28.3 3.8 0.039 13.8 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain Pyr_redox_3 PF13738.1 GAM24342.1 - 0.0059 16.6 0.1 0.055 13.5 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.1 GAM24342.1 - 0.0081 15.7 1.9 0.89 9.2 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM24342.1 - 0.064 13.2 1.2 0.56 10.2 0.9 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Cloacin PF03515.9 GAM24342.1 - 0.077 12.2 0.7 0.18 10.9 0.3 1.7 2 0 0 2 2 2 0 Colicin-like bacteriocin tRNase domain SR-25 PF10500.4 GAM24342.1 - 0.14 11.6 2.5 0.21 11.0 1.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EF-hand_10 PF14788.1 GAM24342.1 - 0.22 11.2 1.4 12 5.6 0.2 2.5 2 0 0 2 2 2 0 EF hand Ldh_1_C PF02866.13 GAM24343.1 - 3.5e-38 131.0 0.0 1.8e-37 128.7 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 GAM24343.1 - 2.7e-33 114.7 0.3 4.9e-33 113.9 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Sec1 PF00995.18 GAM24344.1 - 1.8e-153 512.2 9.1 2e-153 512.0 6.3 1.0 1 0 0 1 1 1 1 Sec1 family Rotavirus_VP7 PF05868.6 GAM24344.1 - 0.042 13.0 1.4 0.057 12.5 0.1 1.8 2 0 0 2 2 2 0 Rotavirus major outer capsid protein VP7 B12-binding PF02310.14 GAM24344.1 - 0.13 12.0 0.0 1 9.2 0.0 2.3 1 1 1 2 2 2 0 B12 binding domain Pkinase_Tyr PF07714.12 GAM24346.1 - 7.9e-70 234.8 0.0 1.5e-69 233.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM24346.1 - 1.7e-67 227.3 0.0 2.6e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 GAM24346.1 - 3.5e-05 22.8 0.0 9.2e-05 21.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like NLPC_P60 PF00877.14 GAM24347.1 - 1.3e-12 47.4 0.6 1.6e-12 47.1 0.4 1.2 1 0 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.6 GAM24347.1 - 0.069 12.4 0.0 0.33 10.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Amidase_5 PF05382.8 GAM24347.1 - 0.37 10.4 6.2 0.24 11.0 2.6 1.9 2 1 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase MCM PF00493.18 GAM24348.1 - 5.2e-129 429.7 0.0 7.8e-129 429.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM24348.1 - 1.8e-10 41.3 0.0 6.6e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM24348.1 - 2.6e-08 33.2 0.0 3.2e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 GAM24348.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 GAM24348.1 - 0.0019 17.8 0.0 0.0045 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM24348.1 - 0.025 14.3 0.0 0.092 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sulfate_transp PF00916.15 GAM24350.1 - 1.5e-65 221.0 18.8 1.5e-65 221.0 13.0 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM24350.1 - 1.6e-30 104.5 3.4 1.6e-30 104.5 2.3 3.7 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM24350.1 - 9e-08 31.5 0.0 1.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF4191 PF13829.1 GAM24350.1 - 0.82 8.7 5.5 8 5.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) tRNA-synt_1d PF00750.14 GAM24351.1 - 1.5e-86 290.4 2.5 1.9e-86 290.1 1.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 GAM24351.1 - 2e-25 89.0 0.2 4.2e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 GAM24351.1 - 2.8e-08 34.1 1.1 6.3e-08 33.0 0.2 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain CAP PF00188.21 GAM24353.1 - 6e-11 42.9 0.2 1.2e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SSP160 PF06933.6 GAM24353.1 - 0.13 10.2 4.5 0.19 9.7 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 GAM24353.1 - 0.2 11.4 5.6 0.43 10.3 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FNIP PF05725.7 GAM24354.1 - 4.2e-35 119.4 25.4 9.2e-13 47.9 0.0 8.3 5 3 3 8 8 8 6 FNIP Repeat LRR_7 PF13504.1 GAM24354.1 - 0.035 14.2 2.3 24 5.7 0.2 5.3 5 0 0 5 5 5 0 Leucine rich repeat GST_N_3 PF13417.1 GAM24355.1 - 6.3e-11 42.3 0.1 1.6e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM24355.1 - 2.6e-10 40.1 0.1 4.1e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM24355.1 - 2.8e-10 40.0 0.0 5.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM24355.1 - 4.3e-08 33.2 0.0 9.2e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM24355.1 - 1.9e-07 30.8 0.1 4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM24355.1 - 1.3e-06 28.7 0.1 2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NMO PF03060.10 GAM24356.1 - 3.3e-40 138.2 0.0 3e-39 135.0 0.0 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 GAM24356.1 - 1.1e-05 24.6 0.1 1.6e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 GAM24356.1 - 4e-05 22.6 0.1 5.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 GAM24356.1 - 0.00045 19.5 0.0 0.0014 17.9 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein Trp_syntA PF00290.15 GAM24356.1 - 0.0006 18.4 0.1 0.0051 15.3 0.0 2.0 2 0 0 2 2 2 1 Tryptophan synthase alpha chain IMPDH PF00478.20 GAM24356.1 - 0.0016 17.4 1.6 0.0027 16.6 1.1 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DUF561 PF04481.7 GAM24356.1 - 0.025 13.5 0.2 0.035 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) AMP-binding PF00501.23 GAM24359.1 - 1.5e-89 300.2 0.0 1.8e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM24359.1 - 9.3e-17 61.7 0.0 2.2e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1322 PF07032.6 GAM24359.1 - 0.14 12.4 0.2 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) Elongin_A PF06881.6 GAM24360.1 - 3.1e-16 59.7 0.3 4.7e-16 59.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A API5 PF05918.6 GAM24360.1 - 0.013 14.0 0.2 0.016 13.7 0.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3994 PF13159.1 GAM24360.1 - 0.074 13.3 0.1 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) Med15 PF09606.5 GAM24361.1 - 0.51 8.4 37.6 0.7 8.0 26.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Borrelia_P83 PF05262.6 GAM24361.1 - 0.69 8.1 11.4 0.94 7.6 7.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MMR1 PF08505.5 GAM24361.1 - 0.71 9.8 14.2 1 9.3 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein APG6 PF04111.7 GAM24361.1 - 0.97 8.4 16.9 1.5 7.7 11.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HlyD_2 PF12700.2 GAM24361.1 - 6.1 5.8 10.8 9.1 5.3 7.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein SLBP_RNA_bind PF15247.1 GAM24362.1 - 5.4e-29 99.7 1.5 5.4e-29 99.7 1.0 2.4 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SRP-alpha_N PF04086.8 GAM24362.1 - 0.28 10.5 6.2 0.55 9.5 4.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal La PF05383.12 GAM24363.1 - 8.1e-15 54.3 0.0 2.7e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 La domain Thioredoxin PF00085.15 GAM24364.1 - 7.7e-21 73.7 0.0 9.1e-21 73.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 GAM24364.1 - 1.8e-05 24.6 0.0 2.3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM24364.1 - 3.3e-05 24.0 0.3 0.003 17.7 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 GAM24364.1 - 3.8e-05 23.2 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAM24364.1 - 0.00028 20.9 0.1 0.0015 18.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 GAM24364.1 - 0.0014 18.3 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM24364.1 - 0.003 17.0 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin ADH_zinc_N PF00107.21 GAM24365.1 - 3.4e-23 81.5 0.0 5.7e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM24365.1 - 2.6e-08 34.8 0.0 5.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RecA PF00154.16 GAM24366.1 - 2.2e-159 529.7 0.6 2.7e-159 529.4 0.4 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.6 GAM24366.1 - 4.4e-13 48.7 0.0 1.3e-12 47.1 0.0 1.7 1 1 0 1 1 1 1 Rad51 KaiC PF06745.8 GAM24366.1 - 8.1e-09 34.9 1.7 1.9e-07 30.4 0.2 3.0 2 1 0 2 2 2 1 KaiC AAA_25 PF13481.1 GAM24366.1 - 3.3e-06 26.6 0.0 9.5e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM24366.1 - 0.0007 19.7 0.2 0.0075 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM24366.1 - 0.0021 18.2 1.3 0.0091 16.1 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM24366.1 - 0.012 15.3 1.5 0.029 14.0 0.0 2.5 3 1 0 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 GAM24366.1 - 0.016 15.4 1.6 0.033 14.4 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_10 PF12846.2 GAM24366.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_35 PF14516.1 GAM24366.1 - 0.02 13.5 0.0 0.036 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 GAM24366.1 - 0.027 14.3 0.0 0.1 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain TK PF00265.13 GAM24366.1 - 0.029 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase CobU PF02283.11 GAM24366.1 - 0.029 13.7 0.0 0.077 12.3 0.0 1.7 1 1 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase WD40 PF00400.27 GAM24368.1 - 2.8e-38 128.4 1.6 2.1e-11 43.2 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 GAM24368.1 - 7.9e-08 32.2 0.3 0.00013 21.7 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 GAM24368.1 - 0.00097 17.0 0.2 0.024 12.5 0.1 2.2 1 1 0 2 2 2 1 IKI3 family CDK2AP PF09806.4 GAM24368.1 - 0.0022 18.2 1.4 0.0032 17.7 1.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Nup160 PF11715.3 GAM24368.1 - 0.0056 14.8 5.7 0.0094 14.1 0.1 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 GAM24368.1 - 0.063 12.7 0.0 4.5 6.8 0.0 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Period_C PF12114.3 GAM24368.1 - 0.45 10.0 7.7 0.79 9.2 5.3 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 GAM24368.1 - 4.2 6.7 9.9 6.9 6.0 6.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HXXSHH PF07586.6 GAM24368.1 - 4.4 6.1 6.8 10 4.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) CAF-1_p150 PF11600.3 GAM24368.1 - 5.9 6.1 5.0 8.7 5.6 3.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SSP160 PF06933.6 GAM24369.1 - 0.0048 14.9 2.6 0.0045 15.0 1.8 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 SoxE PF06525.6 GAM24369.1 - 0.082 12.1 1.3 0.096 11.9 0.9 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Mucin PF01456.12 GAM24369.1 - 0.63 9.8 11.0 0.77 9.5 7.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Endotoxin_N PF03945.9 GAM24370.1 - 4.1e-27 95.0 4.3 4.1e-27 95.0 3.0 1.9 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Med2 PF11214.3 GAM24370.1 - 0.67 10.0 4.2 1.1 9.2 0.5 2.8 3 0 0 3 3 3 0 Mediator complex subunit 2 KRBA1 PF15287.1 GAM24371.1 - 0.024 13.9 0.2 0.024 13.9 0.1 3.8 3 0 0 3 3 3 0 KRBA1 family repeat F-box-like PF12937.2 GAM24372.1 - 1.5e-06 27.8 0.4 1.5e-06 27.8 0.3 2.3 2 0 0 2 2 2 1 F-box-like BTK PF00779.14 GAM24372.1 - 0.00016 21.2 1.0 0.00038 19.9 0.7 1.6 1 0 0 1 1 1 1 BTK motif F-box PF00646.28 GAM24372.1 - 0.00024 20.6 0.1 0.00087 18.8 0.1 2.0 1 0 0 1 1 1 1 F-box domain NinE PF05322.6 GAM24372.1 - 0.017 14.8 1.6 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 NINE Protein Elongin_A PF06881.6 GAM24372.1 - 0.095 13.0 0.4 0.23 11.8 0.2 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RNA_polI_A34 PF08208.6 GAM24373.1 - 7.7e-10 38.7 121.2 1.5e+04 -18.6 84.0 3.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Lustrin_cystein PF14625.1 GAM24374.1 - 0.0049 16.9 10.3 0.0049 16.9 7.2 5.3 4 1 1 5 5 5 1 Lustrin, cysteine-rich repeated domain TMEM154 PF15102.1 GAM24374.1 - 0.87 9.2 13.5 2.1 8.0 9.2 1.7 2 0 0 2 2 2 0 TMEM154 protein family UPF1_Zn_bind PF09416.5 GAM24375.1 - 4.5e-66 221.1 5.3 1.1e-65 219.8 3.3 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 GAM24375.1 - 2e-59 200.3 0.0 3.7e-59 199.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM24375.1 - 6.8e-52 176.3 0.3 6.8e-52 176.3 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM24375.1 - 3.9e-11 42.8 0.0 2.1e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM24375.1 - 4e-11 42.5 0.3 1.2e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 GAM24375.1 - 0.00011 21.2 0.7 0.0034 16.3 0.0 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 GAM24375.1 - 0.00086 19.1 3.2 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2946 PF11162.3 GAM24375.1 - 0.0031 17.6 1.6 0.0088 16.2 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) DEAD PF00270.24 GAM24375.1 - 0.0039 16.6 0.2 0.01 15.3 0.2 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 GAM24375.1 - 0.0079 15.1 0.0 0.43 9.4 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase TerY-C PF15616.1 GAM24375.1 - 0.016 15.1 0.4 0.053 13.4 0.3 1.9 1 0 0 1 1 1 0 TerY-C metal binding domain PhoH PF02562.11 GAM24375.1 - 0.029 13.5 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 GAM24375.1 - 0.032 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.9 GAM24375.1 - 0.037 13.7 0.1 0.073 12.8 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_18 PF13238.1 GAM24375.1 - 0.066 13.5 0.0 0.54 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 GAM24375.1 - 0.068 13.3 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain UvrD_C_2 PF13538.1 GAM24375.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 GAM24375.1 - 0.12 12.0 0.1 0.85 9.3 0.0 2.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM24375.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 GAM24375.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3126 PF11324.3 GAM24375.1 - 0.15 11.7 0.0 0.46 10.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3126) Helicase_RecD PF05127.9 GAM24375.1 - 0.2 11.2 0.5 0.5 9.9 0.0 1.9 2 0 0 2 2 1 0 Helicase Ank_3 PF13606.1 GAM24378.1 - 0.013 15.6 0.9 42 4.8 0.1 4.5 4 0 0 4 4 4 0 Ankyrin repeat zf-C2H2_4 PF13894.1 GAM24378.1 - 0.1 13.0 0.5 0.32 11.4 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PGP_phosphatase PF09419.5 GAM24379.1 - 2.5e-43 147.3 0.0 3.3e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 GAM24379.1 - 1.6e-07 30.9 0.0 3.1e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 GAM24379.1 - 6.7e-07 29.9 0.0 0.0048 17.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM24379.1 - 0.0074 16.5 0.0 0.057 13.6 0.0 1.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM24379.1 - 0.03 14.4 0.1 2.9 8.0 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF99 PF01949.11 GAM24379.1 - 0.052 12.6 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 PCI PF01399.22 GAM24380.1 - 4.9e-16 58.9 0.1 1.3e-15 57.6 0.1 1.8 1 0 0 1 1 1 1 PCI domain p25-alpha PF05517.7 GAM24380.1 - 0.13 12.5 0.6 0.2 11.9 0.4 1.4 1 0 0 1 1 1 0 p25-alpha WD40 PF00400.27 GAM24381.1 - 1.5e-17 62.6 3.2 1.1e-06 28.2 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat F-box-like PF12937.2 GAM24381.1 - 2.5e-10 39.9 0.4 7.7e-10 38.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM24381.1 - 5.1e-06 25.9 0.1 1.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain START PF01852.14 GAM24381.1 - 1.4e-05 24.4 0.1 0.00043 19.6 0.0 2.5 2 0 0 2 2 2 1 START domain PRANC PF09372.5 GAM24381.1 - 0.02 14.8 0.0 0.14 12.1 0.0 2.5 1 0 0 1 1 1 0 PRANC domain Glyoxalase PF00903.20 GAM24382.1 - 4.6e-22 78.3 1.2 4.2e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 GAM24382.1 - 2.4e-10 40.4 0.2 0.00068 19.6 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM24382.1 - 2.2e-09 37.8 0.0 0.00024 21.6 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 GAM24382.1 - 1.2e-05 25.2 0.1 5.6e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 GAM24382.1 - 3.8e-05 23.6 0.1 0.92 9.3 0.0 4.1 4 1 0 4 4 4 2 Glyoxalase-like domain GATA PF00320.22 GAM24386.1 - 2.8e-16 58.5 5.6 2.8e-16 58.5 3.9 2.0 2 0 0 2 2 2 1 GATA zinc finger OmpH PF03938.9 GAM24386.1 - 0.0014 18.5 11.3 0.0014 18.5 7.8 3.1 3 0 0 3 3 3 2 Outer membrane protein (OmpH-like) PAT1 PF09770.4 GAM24386.1 - 0.027 12.7 42.2 0.042 12.0 29.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cytochrom_C_2 PF01322.15 GAM24386.1 - 0.11 13.0 0.2 0.11 13.0 0.1 3.2 2 1 1 3 3 3 0 Cytochrome C' DUF4019 PF13211.1 GAM24386.1 - 0.16 12.2 3.6 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) TF_Zn_Ribbon PF08271.7 GAM24386.1 - 0.31 10.3 2.1 0.64 9.3 1.5 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding NLPC_P60 PF00877.14 GAM24387.1 - 8.9e-12 44.7 0.1 8.9e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 NlpC/P60 family DUF1175 PF06672.6 GAM24387.1 - 0.0077 15.5 0.2 0.059 12.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1175) Ibs_toxin PF13956.1 GAM24387.1 - 5.3 6.9 6.1 8.7 6.2 4.3 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Dynein_heavy PF03028.10 GAM24388.1 - 1.3e-213 710.9 3.4 4.2e-213 709.3 2.3 1.9 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 GAM24388.1 - 3.8e-168 560.4 15.0 3.8e-168 560.4 10.4 4.6 6 1 0 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 GAM24388.1 - 6.4e-129 430.0 12.3 6.4e-129 430.0 8.5 4.8 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 GAM24388.1 - 5.2e-86 287.9 0.0 2.3e-85 285.8 0.0 2.1 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 GAM24388.1 - 1e-48 165.1 0.0 5.4e-48 162.8 0.0 2.3 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 GAM24388.1 - 2.3e-44 151.3 0.0 1.4e-42 145.5 0.0 2.7 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 GAM24388.1 - 2.6e-42 144.7 14.9 5.8e-42 143.6 10.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 GAM24388.1 - 8e-34 116.3 0.0 1.3e-13 50.9 0.0 6.1 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 GAM24388.1 - 2.5e-21 76.0 0.0 1.7e-20 73.2 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 GAM24388.1 - 3.6e-14 53.0 0.0 0.0019 18.3 0.0 6.3 5 0 0 5 5 5 4 AAA domain AAA PF00004.24 GAM24388.1 - 6.7e-13 48.9 0.0 0.00088 19.4 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM24388.1 - 4.5e-09 36.5 0.3 2.2 8.2 0.0 6.2 5 1 0 5 5 5 2 AAA ATPase domain AAA_33 PF13671.1 GAM24388.1 - 4.2e-08 33.1 0.0 0.35 10.7 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 GAM24388.1 - 9.3e-06 26.4 0.0 3.7 8.3 0.0 6.0 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 GAM24388.1 - 6.6e-05 22.5 0.0 0.35 10.6 0.0 3.6 3 0 0 3 3 3 1 Part of AAA domain T2SE PF00437.15 GAM24388.1 - 0.00027 19.9 0.0 0.088 11.6 0.0 3.5 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_29 PF13555.1 GAM24388.1 - 0.00053 19.4 0.0 2.1 7.9 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 GAM24388.1 - 0.002 17.2 2.8 0.52 9.4 0.0 3.5 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI Reo_sigmaC PF04582.7 GAM24388.1 - 0.82 8.7 9.3 1 8.4 1.2 3.8 4 0 0 4 4 4 0 Reovirus sigma C capsid protein AAA_25 PF13481.1 GAM24388.1 - 0.96 8.8 4.5 0.52 9.6 0.0 2.9 4 0 0 4 4 2 0 AAA domain Frizzled PF01534.12 GAM24390.1 - 9.2e-10 37.8 18.7 1.3e-09 37.2 13.0 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.17 GAM24390.1 - 3.9e-05 23.9 2.1 3.9e-05 23.9 1.5 1.9 2 0 0 2 2 2 1 Fz domain Isochorismatase PF00857.15 GAM24391.1 - 1.3e-25 90.3 1.0 2.4e-25 89.4 0.7 1.3 1 1 0 1 1 1 1 Isochorismatase family Mito_carr PF00153.22 GAM24392.1 - 6.1e-73 240.6 2.6 1.9e-28 98.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S21 PF01165.15 GAM24392.1 - 0.047 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 Nramp PF01566.13 GAM24393.1 - 4.6e-121 403.9 12.2 4.6e-121 403.9 8.4 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF2207 PF09972.4 GAM24393.1 - 2.7 6.4 10.8 0.46 9.0 3.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) RWP-RK PF02042.10 GAM24394.1 - 0.0027 17.5 0.1 0.0069 16.1 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain PhyH PF05721.8 GAM24396.1 - 9.9e-50 169.5 0.0 1.2e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1273 PF06908.6 GAM24396.1 - 0.063 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Nuc_N PF14448.1 GAM24396.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Nuclease N terminal Mito_carr PF00153.22 GAM24397.1 - 5.6e-68 224.7 2.5 1.2e-22 79.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.19 GAM24398.1 - 1.7e-17 63.2 0.0 4.5e-17 61.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM24398.1 - 6.3e-09 35.8 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM24398.1 - 2.5e-08 34.0 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM24398.1 - 2.2e-07 30.9 0.0 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM24398.1 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM24398.1 - 1.4e-05 24.7 0.0 3.9e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 GAM24398.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM24398.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain cNMP_binding PF00027.24 GAM24399.1 - 1.8e-30 104.5 0.1 4.7e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.22 GAM24399.1 - 3.1e-10 40.0 0.3 6.1e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM24399.1 - 7e-10 38.7 0.2 1.7e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VPS9 PF02204.13 GAM24400.1 - 1.1e-14 54.2 0.0 5.4e-14 52.0 0.0 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SR-25 PF10500.4 GAM24400.1 - 0.038 13.4 2.6 0.077 12.4 1.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VPS9 PF02204.13 GAM24401.1 - 2.9e-11 43.3 0.2 2.4e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Tektin PF03148.9 GAM24401.1 - 0.034 12.6 0.0 0.034 12.6 0.0 1.4 2 0 0 2 2 2 0 Tektin family Mob1_phocein PF03637.12 GAM24403.1 - 1.6e-75 252.5 0.3 1.9e-75 252.3 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family Alpha_L_fucos PF01120.12 GAM24403.1 - 0.094 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase zf-B_box PF00643.19 GAM24404.1 - 8.2e-09 35.2 6.7 1.5e-08 34.3 4.7 1.4 1 0 0 1 1 1 1 B-box zinc finger Sec20 PF03908.8 GAM24404.1 - 0.0079 15.8 0.3 0.02 14.5 0.2 1.7 1 0 0 1 1 1 1 Sec20 IBR PF01485.16 GAM24404.1 - 0.037 13.8 4.1 0.073 12.9 2.8 1.4 1 0 0 1 1 1 0 IBR domain DUF310 PF03750.8 GAM24404.1 - 0.074 13.2 2.2 1.1 9.4 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF310) TBPIP PF07106.8 GAM24404.1 - 0.078 12.5 0.3 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C3HC4_2 PF13923.1 GAM24404.1 - 0.15 12.0 3.7 0.28 11.2 2.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fib_alpha PF08702.5 GAM24404.1 - 0.2 11.8 3.5 2.7 8.0 0.1 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Kelch_6 PF13964.1 GAM24405.1 - 0.027 14.6 0.1 6.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Kelch motif Rax2 PF12768.2 GAM24405.1 - 0.038 13.1 0.0 0.078 12.1 0.0 1.3 1 1 0 1 1 1 0 Cortical protein marker for cell polarity Ribosomal_S19 PF00203.16 GAM24406.1 - 3.2e-28 97.1 0.4 5e-28 96.5 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S19 Nup84_Nup100 PF04121.8 GAM24407.1 - 1.7e-110 369.8 17.1 2.6e-110 369.1 11.8 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 CH PF00307.26 GAM24408.1 - 2.1e-36 124.2 6.3 5.6e-15 55.3 0.5 5.2 5 0 0 5 5 5 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM24408.1 - 1e-06 28.3 0.9 0.00046 19.7 0.2 3.2 2 0 0 2 2 2 2 CAMSAP CH domain zf-C3HC4 PF00097.20 GAM24409.1 - 1.2e-05 24.9 21.1 1.2e-05 24.9 14.7 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM24409.1 - 0.00034 20.2 19.2 0.00034 20.2 13.3 3.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAM24409.1 - 0.00091 19.0 22.1 0.00091 19.0 15.3 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAM24409.1 - 0.0013 18.3 17.9 0.0013 18.3 12.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM24409.1 - 0.0018 17.9 15.8 0.0018 17.9 10.9 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 GAM24409.1 - 0.0034 17.3 21.4 0.0034 17.3 14.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 GAM24409.1 - 0.0057 16.5 14.1 0.0057 16.5 9.8 3.2 2 1 0 2 2 2 1 B-box zinc finger Profilin PF00235.14 GAM24410.1 - 3.6e-36 123.9 0.2 4e-36 123.7 0.1 1.0 1 0 0 1 1 1 1 Profilin GSAP-16 PF14959.1 GAM24411.1 - 6e-24 84.0 1.1 1.6e-23 82.6 0.4 2.1 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term RWP-RK PF02042.10 GAM24412.1 - 5e-27 93.4 0.1 8.9e-27 92.6 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.2 GAM24412.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CDK5_activator PF03261.10 GAM24412.1 - 0.15 11.3 14.9 0.22 10.8 10.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Zip PF02535.17 GAM24412.1 - 1.3 7.9 7.8 1.6 7.6 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4140 PF13600.1 GAM24412.1 - 1.3 9.4 6.7 13 6.2 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) EGF_2 PF07974.8 GAM24415.1 - 6.8e-06 26.1 7.9 1.3e-05 25.2 5.5 1.5 1 0 0 1 1 1 1 EGF-like domain TMEM210 PF15195.1 GAM24415.1 - 0.011 15.8 0.9 0.024 14.7 0.6 1.6 1 0 0 1 1 1 0 TMEM210 family EGF PF00008.22 GAM24415.1 - 0.46 10.4 7.6 1 9.3 5.3 1.5 1 0 0 1 1 1 0 EGF-like domain BING4CT PF08149.6 GAM24416.1 - 4.3e-31 106.2 0.7 3.2e-30 103.4 0.0 2.8 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 GAM24416.1 - 5.3e-08 32.4 0.1 3.7e-05 23.4 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM24416.1 - 2.7e-05 23.7 0.0 0.00012 21.6 0.0 1.9 1 1 1 2 2 2 1 PQQ-like domain FixO PF02433.10 GAM24416.1 - 0.11 11.8 1.9 0.26 10.6 1.3 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Nop25 PF09805.4 GAM24417.1 - 5.3e-16 58.9 18.5 5.3e-16 58.9 12.8 3.9 2 1 2 4 4 4 1 Nucleolar protein 12 (25kDa) Nop14 PF04147.7 GAM24417.1 - 0.12 10.3 37.0 0.19 9.6 25.7 1.3 1 0 0 1 1 1 0 Nop14-like family APP_amyloid PF10515.4 GAM24417.1 - 2.4 8.4 5.3 0.66 10.2 0.8 2.2 2 0 0 2 2 2 0 beta-amyloid precursor protein C-terminus ANAPC15 PF15243.1 GAM24417.1 - 4.6 7.3 29.2 0.33 11.0 6.5 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Cupin_8 PF13621.1 GAM24418.1 - 1.9e-23 83.2 0.2 1.9e-23 83.2 0.1 2.0 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 GAM24418.1 - 8e-12 45.4 3.5 8.9e-08 32.3 0.0 2.8 3 0 0 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.7 GAM24418.1 - 3.5e-06 26.5 0.1 9.9e-06 25.0 0.1 1.8 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 GAM24418.1 - 0.016 14.6 0.0 0.058 12.9 0.0 1.9 2 0 0 2 2 2 0 Cupin domain GPI PF06560.6 GAM24418.1 - 0.085 11.8 0.0 0.18 10.7 0.0 1.6 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Condensation PF00668.15 GAM24418.1 - 0.16 10.7 2.4 0.34 9.7 1.6 1.4 1 0 0 1 1 1 0 Condensation domain MAGE PF01454.14 GAM24418.1 - 1.8 7.8 5.1 0.25 10.6 0.7 1.6 2 0 0 2 2 2 0 MAGE family SPA PF08616.5 GAM24419.1 - 4.3e-12 45.7 0.1 9.1e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAM24419.1 - 4.2e-09 35.3 1.6 6.3e-09 34.7 0.0 2.2 2 1 0 2 2 2 1 Transport protein Avl9 DENN PF02141.16 GAM24419.1 - 0.00011 22.0 2.6 0.00043 20.0 0.3 2.9 2 1 0 2 2 2 1 DENN (AEX-3) domain Afi1 PF07792.7 GAM24419.1 - 0.00042 20.3 0.1 0.00042 20.3 0.0 2.2 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking F-box-like PF12937.2 GAM24420.1 - 6.6e-09 35.3 0.1 1.5e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM24420.1 - 3.9e-08 32.7 0.2 9.4e-08 31.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain A2M_N_2 PF07703.9 GAM24420.1 - 0.051 13.3 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region R3H-assoc PF13902.1 GAM24421.1 - 1.9e-23 82.8 2.6 1.9e-23 82.8 1.8 1.6 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 GAM24421.1 - 0.0076 15.9 0.1 0.019 14.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain Glyco_hydro_9 PF00759.14 GAM24422.1 - 3.8e-132 441.3 3.2 5.2e-132 440.9 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 WD40 PF00400.27 GAM24423.1 - 3.8e-46 153.3 33.1 7.4e-11 41.5 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ATG16 PF08614.6 GAM24423.1 - 3.3e-39 134.7 23.1 4.9e-39 134.1 16.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Nup160 PF11715.3 GAM24423.1 - 0.00017 19.8 8.6 0.062 11.4 0.7 4.3 2 2 2 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 GAM24423.1 - 0.034 13.8 0.2 0.59 9.8 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3510 PF12022.3 GAM24423.1 - 0.38 10.8 7.2 3.9 7.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Nup54 PF13874.1 GAM24423.1 - 1.5 8.5 21.5 0.47 10.1 1.1 3.3 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 IncA PF04156.9 GAM24423.1 - 4.5 6.8 24.2 3.1 7.3 7.9 2.6 1 1 1 2 2 2 0 IncA protein SNARE_assoc PF09335.6 GAM24424.1 - 1.5e-28 99.4 4.1 1.5e-28 99.4 2.8 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein RseC_MucC PF04246.7 GAM24424.1 - 6.7 6.2 9.5 3.9 7.0 1.3 2.8 2 1 2 4 4 4 0 Positive regulator of sigma(E), RseC/MucC TILa PF12714.2 GAM24425.1 - 1.8 8.3 29.3 0.35 10.6 1.2 4.0 2 2 2 4 4 4 0 TILa domain FNIP PF05725.7 GAM24426.1 - 2.9e-47 158.3 9.8 5.5e-11 42.2 0.7 5.8 3 1 2 6 6 6 5 FNIP Repeat LRR_8 PF13855.1 GAM24426.1 - 0.0098 15.6 6.1 0.7 9.6 0.0 3.9 4 0 0 4 4 4 2 Leucine rich repeat ATP-grasp_2 PF08442.5 GAM24427.1 - 8.5e-75 250.5 0.4 1.2e-74 250.0 0.3 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 GAM24427.1 - 2.1e-27 95.6 2.6 4.5e-27 94.5 1.8 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 GAM24427.1 - 8.7e-13 47.9 0.2 1.3e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 GAM24427.1 - 0.00041 19.9 0.7 0.00099 18.7 0.5 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 GAM24427.1 - 0.025 13.3 0.1 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Peripla_BP_3 PF13377.1 GAM24427.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Kelch_1 PF01344.20 GAM24428.1 - 1.1e-23 82.5 15.1 3.1e-06 26.6 0.3 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 GAM24428.1 - 1.1e-16 60.1 12.4 7e-05 22.8 0.1 6.4 2 1 4 6 6 6 4 Kelch motif Kelch_4 PF13418.1 GAM24428.1 - 4.7e-16 58.2 11.2 0.004 16.8 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain zf-B_box PF00643.19 GAM24428.1 - 5.1e-08 32.6 11.2 1e-07 31.6 7.8 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.10 GAM24428.1 - 1.5e-06 27.7 9.2 0.098 12.4 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM24428.1 - 0.00045 20.2 13.0 0.024 14.7 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24428.1 - 0.017 15.0 17.7 0.56 10.2 0.3 4.9 5 0 0 5 5 5 0 Kelch motif BBS2_N PF14781.1 GAM24428.1 - 0.062 12.9 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal FNIP PF05725.7 GAM24429.1 - 6.3e-56 186.0 26.2 6.5e-13 48.4 0.5 6.5 3 1 5 8 8 8 7 FNIP Repeat LRR_7 PF13504.1 GAM24429.1 - 1.7 9.2 5.6 83 4.0 0.1 4.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 GAM24429.1 - 5.1 7.5 7.1 36 4.9 0.1 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat Epimerase PF01370.16 GAM24430.1 - 2.6e-29 102.3 0.0 3.5e-29 101.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM24430.1 - 1.8e-18 66.2 0.0 2.9e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAM24430.1 - 2.3e-11 43.1 0.1 3.4e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAM24430.1 - 1.5e-09 37.1 0.0 2.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM24430.1 - 2.6e-09 37.2 0.1 1.9e-08 34.3 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAM24430.1 - 4.8e-08 32.2 0.0 4.5e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 GAM24430.1 - 2.2e-06 27.4 0.0 1.2e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 GAM24430.1 - 0.00057 18.9 0.1 0.00092 18.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase MoeZ_MoeB PF05237.8 GAM24430.1 - 0.016 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 MoeZ/MoeB domain NAD_binding_10 PF13460.1 GAM24430.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding zf-Di19 PF05605.7 GAM24431.1 - 1.2e-18 66.8 1.5 2.1e-18 66.1 1.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Di19_C PF14571.1 GAM24431.1 - 0.009 16.3 6.6 0.009 16.3 4.6 3.0 4 0 0 4 4 4 1 Stress-induced protein Di19, C-terminal Elf1 PF05129.8 GAM24431.1 - 0.088 12.5 0.4 0.19 11.4 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2296 PF10058.4 GAM24431.1 - 0.72 9.6 3.8 3.6 7.4 0.2 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1 PF03811.8 GAM24431.1 - 0.84 9.1 4.2 0.45 10.0 0.2 2.3 2 0 0 2 2 2 0 InsA N-terminal domain Bap31 PF05529.7 GAM24432.1 - 7.2e-36 123.4 8.3 8.8e-36 123.1 5.8 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like HALZ PF02183.13 GAM24432.1 - 4e-06 26.4 6.9 3.4e-05 23.4 0.7 2.3 1 1 1 2 2 2 2 Homeobox associated leucine zipper DUF972 PF06156.8 GAM24432.1 - 0.0002 21.6 8.0 0.00064 20.0 4.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF972) DUF3450 PF11932.3 GAM24432.1 - 0.00028 20.2 2.1 0.00095 18.5 1.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 GAM24432.1 - 0.0032 17.3 8.2 0.0044 16.8 5.7 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.8 GAM24432.1 - 0.0079 14.3 9.1 0.01 13.9 6.3 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein IncA PF04156.9 GAM24432.1 - 0.0084 15.7 3.6 0.0084 15.7 2.5 2.2 3 0 0 3 3 3 1 IncA protein DUF1843 PF08898.5 GAM24432.1 - 0.01 15.8 2.8 0.25 11.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) HOOK PF05622.7 GAM24432.1 - 0.016 13.0 8.4 0.021 12.6 5.8 1.1 1 0 0 1 1 1 0 HOOK protein DUF342 PF03961.8 GAM24432.1 - 0.021 13.2 4.1 0.022 13.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 GAM24432.1 - 0.022 14.2 13.0 0.17 11.4 0.2 3.0 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.1 GAM24432.1 - 0.044 12.9 11.8 0.083 12.0 8.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V-ATPase_G PF03179.10 GAM24432.1 - 0.068 13.4 8.3 0.1 12.8 5.7 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2935 PF11155.3 GAM24432.1 - 0.078 13.0 2.3 0.14 12.2 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Fzo_mitofusin PF04799.8 GAM24432.1 - 0.2 11.0 3.8 0.34 10.2 2.6 1.3 1 0 0 1 1 1 0 fzo-like conserved region Seryl_tRNA_N PF02403.17 GAM24432.1 - 0.27 11.2 11.6 1.2 9.2 6.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Polysacc_synt PF01943.12 GAM24432.1 - 0.34 10.1 6.5 0.16 11.1 3.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_MLP1_2 PF07926.7 GAM24432.1 - 0.9 9.2 11.5 4.8 6.9 7.9 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.1 GAM24432.1 - 1 8.2 6.2 2.8 6.8 4.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 GAM24432.1 - 2.5 7.0 11.7 3.7 6.5 8.1 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 GAM24432.1 - 5 7.0 13.6 0.17 11.7 2.0 3.0 2 2 2 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.1 GAM24432.1 - 6.2 6.6 12.7 0.078 12.8 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) WD40 PF00400.27 GAM24433.1 - 1.9e-10 40.2 12.7 0.14 12.1 0.0 9.2 8 1 0 8 8 8 4 WD domain, G-beta repeat LRR_6 PF13516.1 GAM24434.1 - 3.2e-12 45.1 34.3 0.012 15.6 0.0 10.8 12 1 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.2 GAM24434.1 - 4e-09 35.8 21.5 0.028 14.0 0.5 6.3 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM24434.1 - 1.2e-05 24.6 9.1 0.91 9.7 0.3 6.9 6 2 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 GAM24434.1 - 0.00025 20.7 9.6 0.00095 18.8 0.8 4.7 5 1 0 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 GAM24434.1 - 0.00058 19.6 2.7 23 5.7 0.0 7.1 7 0 0 7 7 7 1 Leucine rich repeat Lipase_GDSL_2 PF13472.1 GAM24435.1 - 2.4e-12 47.3 0.0 4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 GAM24435.1 - 4.3e-10 39.8 0.0 8.8e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CN_hydrolase PF00795.17 GAM24436.1 - 1.1e-34 119.4 0.0 1.5e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ABC_tran PF00005.22 GAM24437.1 - 5.4e-25 88.2 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAM24437.1 - 4.2e-17 62.1 36.3 1.2e-16 60.6 25.1 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM24437.1 - 3.3e-15 56.8 0.0 6.8e-10 39.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC2_membrane_5 PF13346.1 GAM24437.1 - 0.0037 16.5 21.7 0.0037 16.5 15.0 2.8 4 0 0 4 4 4 1 ABC-2 family transporter protein AAA_15 PF13175.1 GAM24437.1 - 0.013 14.5 0.0 0.27 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAM24437.1 - 0.062 12.8 0.2 0.062 12.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM24437.1 - 0.076 13.3 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 GAM24437.1 - 0.09 11.9 0.1 8.6 5.5 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain DS PF01916.12 GAM24438.1 - 7.8e-138 458.6 0.0 9.3e-138 458.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Na_Ca_ex PF01699.19 GAM24440.1 - 1.2e-13 50.8 9.4 1.7e-13 50.3 6.5 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein MARVEL PF01284.18 GAM24440.1 - 0.82 9.4 11.9 0.12 12.2 1.8 2.3 2 0 0 2 2 2 0 Membrane-associating domain Ribosomal_S9 PF00380.14 GAM24442.1 - 6.3e-32 110.3 0.1 1e-31 109.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SR-25 PF10500.4 GAM24442.1 - 0.15 11.5 10.6 0.25 10.7 7.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OATP PF03137.15 GAM24443.1 - 0.013 13.5 0.0 0.02 12.9 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Claudin_3 PF06653.6 GAM24443.1 - 0.27 10.9 11.5 0.82 9.3 7.9 1.8 1 1 0 1 1 1 0 Tight junction protein, Claudin-like MARVEL PF01284.18 GAM24443.1 - 0.78 9.5 9.7 0.65 9.8 5.1 2.1 1 1 1 2 2 2 0 Membrane-associating domain Acyl-CoA_dh_1 PF00441.19 GAM24444.1 - 5.5e-11 42.7 0.2 2e-10 40.9 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM24444.1 - 6.1e-10 38.4 0.1 1.2e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.14 GAM24444.1 - 3.6e-08 32.9 0.0 6.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_2 PF08028.6 GAM24444.1 - 0.041 14.1 0.2 0.3 11.3 0.0 2.5 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 GAM24444.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal GSDH PF07995.6 GAM24445.1 - 5.1e-17 61.9 0.1 9.3e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Rifin_STEVOR PF02009.11 GAM24445.1 - 0.013 15.1 3.4 0.023 14.3 2.3 1.4 1 0 0 1 1 1 0 Rifin/stevor family CBM_10 PF02013.11 GAM24445.1 - 1.5 9.1 8.5 4.6 7.6 0.6 3.2 2 1 0 2 2 2 0 Cellulose or protein binding domain Plasmodium_Vir PF05795.6 GAM24445.1 - 5.8 6.0 6.4 8.4 5.4 4.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF605 PF04652.11 GAM24445.1 - 9.5 5.4 21.7 14 4.9 15.0 1.1 1 0 0 1 1 1 0 Vta1 like SNARE PF05739.14 GAM24446.1 - 1.2e-15 56.9 7.1 6.8e-10 38.4 1.1 2.6 2 0 0 2 2 2 2 SNARE domain GRAM PF02893.15 GAM24446.1 - 3.4e-10 39.3 0.0 7.3e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.3 GAM24446.1 - 1.8e-07 31.1 7.4 8.1e-06 25.8 0.9 2.7 2 1 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus bPH_3 PF14470.1 GAM24446.1 - 0.009 16.2 1.1 0.039 14.2 0.2 2.2 2 0 0 2 2 2 1 Bacterial PH domain M_domain PF12938.2 GAM24446.1 - 0.063 13.0 10.1 0.1 12.4 7.0 1.3 1 0 0 1 1 1 0 M domain of GW182 NPV_P10 PF05531.7 GAM24446.1 - 0.063 13.5 0.4 29 4.9 0.2 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 GAM24446.1 - 0.29 11.4 2.9 3.4 8.0 0.2 2.3 2 0 0 2 2 2 0 Snapin/Pallidin FliJ PF02050.11 GAM24446.1 - 2.7 8.0 6.3 2.4 8.2 0.2 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein ubiquitin PF00240.18 GAM24448.1 - 2e-134 437.1 23.1 2.9e-33 113.0 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 GAM24448.1 - 1.2e-75 249.2 21.0 2.1e-18 65.7 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM24448.1 - 9.1e-23 80.3 10.1 0.00042 20.5 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM24448.1 - 1.6e-18 66.8 0.3 0.0082 15.8 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM24448.1 - 2.9e-13 49.6 1.6 0.22 11.3 0.0 4.8 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM24448.1 - 2e-12 47.1 0.8 0.38 10.9 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM24448.1 - 1.3e-10 41.1 0.0 1.5 8.8 0.0 4.6 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 GAM24448.1 - 2.8e-06 27.1 4.6 6.4 6.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Big_3_3 PF13750.1 GAM24448.1 - 3.3e-06 26.6 0.0 12 5.3 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Methyltrans_RNA PF04452.9 GAM24448.1 - 7.8e-06 25.1 0.4 2.3 7.3 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase Enterotoxin_b PF01376.13 GAM24448.1 - 1.2e-05 25.0 1.3 16 5.4 0.0 4.1 4 0 0 4 4 4 0 Heat-labile enterotoxin beta chain Corona_NS2A PF05213.7 GAM24448.1 - 1.4e-05 24.5 0.1 13 5.0 0.0 4.0 1 1 0 4 4 4 0 Coronavirus NS2A protein FlgD_ig PF13860.1 GAM24448.1 - 2.6e-05 23.8 5.2 11 5.8 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain IGR PF09597.5 GAM24448.1 - 8.7e-05 22.3 0.0 42 4.1 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif DUF3435 PF11917.3 GAM24448.1 - 0.001 17.8 0.2 26 3.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) Plexin_cytopl PF08337.7 GAM24448.1 - 0.0024 16.2 10.6 5.4 5.1 0.1 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain GABP-alpha PF11620.3 GAM24448.1 - 0.15 12.0 6.4 80 3.3 0.0 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF1628 PF07790.6 GAM24448.1 - 1.1 9.9 6.0 2.3e+02 2.6 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1628) DUF3781 PF12636.2 GAM24448.1 - 1.7 8.6 4.4 2.6e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) ALAD PF00490.16 GAM24449.1 - 2.3e-121 404.6 0.0 2.6e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Patatin PF01734.17 GAM24450.1 - 3.4e-13 49.9 0.1 1.1e-12 48.3 0.1 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase PH PF00169.24 GAM24450.1 - 2.1e-08 34.2 0.8 2.1e-08 34.2 0.5 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM24450.1 - 0.00074 19.7 2.6 0.002 18.3 1.8 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Response_reg PF00072.19 GAM24451.1 - 6.6e-15 55.0 0.0 1.6e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain LRR_4 PF12799.2 GAM24451.1 - 2.2e-08 33.5 23.5 0.0082 15.7 0.9 6.2 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM24451.1 - 2.5e-05 23.8 42.7 0.04 13.9 0.2 10.8 13 0 0 13 13 13 4 Leucine Rich repeat LRR_8 PF13855.1 GAM24451.1 - 4.2e-05 23.2 33.6 0.0075 16.0 1.8 5.7 2 2 4 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 GAM24451.1 - 0.0049 16.7 29.2 2.5 8.4 0.1 9.6 10 0 0 10 10 10 3 Leucine Rich Repeat DUF106 PF01956.11 GAM24452.1 - 3.5e-38 130.7 8.4 3.5e-38 130.7 5.8 2.2 2 1 0 2 2 2 1 Integral membrane protein DUF106 GST_N_3 PF13417.1 GAM24453.1 - 3.1e-15 56.1 0.0 5.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 GAM24453.1 - 3.3e-11 43.1 0.0 7.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM24453.1 - 7.7e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM24453.1 - 4.9e-07 29.6 0.0 9.3e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM24453.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 GAM24453.1 - 0.0046 16.9 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.1 GAM24453.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 GAM24454.1 - 1.1e-05 25.6 0.1 5.2e-05 23.4 0.1 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM24454.1 - 2.3e-05 24.5 0.6 0.51 10.6 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM24454.1 - 0.00063 20.1 0.2 0.079 13.4 0.2 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24454.1 - 0.0021 18.1 0.1 0.26 11.6 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeat Ank PF00023.25 GAM24454.1 - 0.038 13.8 0.1 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 GAM24455.1 - 0.0018 18.5 0.8 0.48 10.8 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) LRR_8 PF13855.1 GAM24456.1 - 8.8e-16 57.4 41.8 2.9e-07 30.1 4.3 3.9 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 GAM24456.1 - 9e-12 44.3 23.9 1.2e-08 34.3 2.1 5.3 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM24456.1 - 2.3e-11 42.0 16.2 0.18 11.9 0.0 7.3 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 GAM24456.1 - 3.5e-06 26.3 21.6 0.11 12.8 0.6 7.2 7 0 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 GAM24456.1 - 0.2 11.1 3.8 0.57 9.7 2.4 1.8 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.1 GAM24456.1 - 0.87 9.8 26.9 3.3 8.0 0.2 6.4 7 0 0 7 7 7 0 Leucine Rich repeat RasGEF PF00617.14 GAM24457.1 - 2.2e-37 128.5 0.1 5e-37 127.4 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM24457.1 - 3.6e-08 33.4 3.0 3.6e-08 33.4 2.1 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.14 GAM24461.1 - 8.6e-36 123.4 0.1 1.3e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM24461.1 - 0.0012 18.8 0.3 0.0035 17.4 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Actin PF00022.14 GAM24462.1 - 2.1e-23 82.4 0.0 3.3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Actin AIG1 PF04548.11 GAM24462.1 - 5.5e-08 32.1 2.1 5.9e-08 32.0 0.1 2.0 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 GAM24462.1 - 3.5e-06 26.9 0.1 9.4e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM24462.1 - 0.0012 18.0 0.1 0.003 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM24462.1 - 0.0034 17.7 2.8 0.0052 17.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter HSP70 PF00012.15 GAM24462.1 - 0.011 13.6 1.1 0.32 8.8 0.0 2.2 2 0 0 2 2 2 0 Hsp70 protein Miro PF08477.8 GAM24462.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 GAM24462.1 - 0.03 13.3 3.2 0.036 13.0 0.1 2.2 2 0 0 2 2 2 0 Septin CobN-Mg_chel PF02514.11 GAM24462.1 - 0.1 9.9 2.2 0.15 9.4 1.5 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Lge1 PF11488.3 GAM24462.1 - 4.1 7.6 9.6 0.83 9.8 1.8 2.7 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 p450 PF00067.17 GAM24463.1 - 5.8e-64 216.3 0.0 6.4e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 GAM24464.1 - 0.0072 16.6 0.4 0.12 12.7 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM24464.1 - 0.015 15.5 0.0 7.8 6.8 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM24465.1 - 3.9e-18 65.5 8.0 0.0013 18.9 0.0 9.0 5 3 3 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM24465.1 - 9.7 6.2 20.8 48 4.0 0.0 9.1 12 0 0 12 12 12 0 Ankyrin repeat Tim44 PF04280.10 GAM24468.1 - 0.0035 17.3 0.1 2.2 8.2 0.0 2.2 1 1 1 2 2 2 2 Tim44-like domain MBA1 PF07961.6 GAM24468.1 - 0.016 14.0 0.7 0.019 13.8 0.5 1.1 1 0 0 1 1 1 0 MBA1-like protein CBM49 PF09478.5 GAM24469.1 - 5.8e-27 93.6 0.1 7.2e-15 54.8 0.1 2.2 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 Imm1 PF14430.1 GAM24469.1 - 0.12 12.5 0.6 0.47 10.6 0.1 2.1 2 1 1 3 3 3 0 Immunity protein Imm1 LRR_4 PF12799.2 GAM24470.1 - 0.064 12.8 6.0 0.23 11.1 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Euplotes_phero PF05842.6 GAM24470.1 - 0.073 13.4 0.3 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein DNA_ligase_A_M PF01068.16 GAM24471.1 - 8.3e-47 159.1 0.0 1.8e-46 158.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAM24471.1 - 2.5e-37 128.3 0.2 2.5e-37 128.3 0.2 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 GAM24471.1 - 1.7e-19 69.9 0.0 3.9e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 GAM24471.1 - 3.7e-13 49.4 1.7 8.6e-10 38.6 0.1 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 GAM24471.1 - 5.1e-09 35.7 0.1 9.9e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 GAM24471.1 - 7e-06 25.8 4.1 0.002 17.8 0.0 3.4 4 0 0 4 4 4 2 mRNA capping enzyme, catalytic domain VWA_2 PF13519.1 GAM24472.1 - 3.6e-20 72.7 0.0 4.8e-18 65.8 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain EF-hand_1 PF00036.27 GAM24472.1 - 3.1e-12 44.8 0.6 1.7e-06 26.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAM24472.1 - 7.6e-12 45.1 0.1 2e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM24472.1 - 6.7e-10 38.4 0.5 4.8e-07 29.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM24472.1 - 3.3e-09 35.8 0.1 4.3e-05 23.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain WWE PF02825.15 GAM24472.1 - 1.8e-06 27.2 0.0 4.5e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 WWE domain EF-hand_9 PF14658.1 GAM24472.1 - 2.8e-06 27.1 0.0 6.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 GAM24472.1 - 2e-05 23.6 0.2 0.00052 19.2 0.0 2.6 2 0 0 2 2 2 1 EF hand ABC2_membrane_3 PF12698.2 GAM24472.1 - 0.0066 15.5 0.8 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein PBP1_TM PF14812.1 GAM24472.1 - 0.19 12.0 3.4 0.46 10.8 2.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribonuc_red_sm PF00268.16 GAM24473.1 - 4.7e-118 393.2 3.2 5.3e-118 393.1 2.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain KTSC PF13619.1 GAM24473.1 - 0.0062 16.1 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 KTSC domain F-box-like PF12937.2 GAM24474.1 - 0.018 14.7 0.1 0.059 13.1 0.0 1.9 1 0 0 1 1 1 0 F-box-like His_biosynth PF00977.16 GAM24474.1 - 0.035 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein E1-E2_ATPase PF00122.15 GAM24475.1 - 3.2e-24 85.2 0.0 8.4e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 GAM24475.1 - 1.6e-13 50.4 0.0 5.6e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM24475.1 - 1.2e-10 41.8 0.1 5.2e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM24475.1 - 5.5e-10 40.0 0.0 3.1e-08 34.3 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM24475.1 - 0.00059 19.4 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 GAM24476.1 - 1.7e-07 31.4 0.0 0.13 12.5 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM24476.1 - 0.00029 21.2 0.6 11 6.7 0.0 4.6 4 1 0 4 4 4 1 Ankyrin repeats (many copies) LINES_C PF14695.1 GAM24476.1 - 0.0064 15.7 0.0 0.017 14.3 0.0 1.7 1 0 0 1 1 1 1 Lines C-terminus Ank_3 PF13606.1 GAM24476.1 - 0.013 15.6 6.4 1.2e+02 3.3 0.0 6.1 7 0 0 7 7 7 0 Ankyrin repeat CRAL_TRIO_2 PF13716.1 GAM24476.1 - 0.037 13.9 0.2 0.17 11.7 0.2 2.0 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Herpes_UL7 PF01677.11 GAM24476.1 - 0.079 12.2 0.1 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Herpesvirus UL7 like Ank PF00023.25 GAM24476.1 - 0.079 12.8 2.6 30 4.6 0.0 5.1 6 1 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.2 GAM24477.1 - 5.4e-11 42.6 0.1 0.03 14.6 0.0 5.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM24477.1 - 1e-06 29.1 4.7 0.34 11.4 0.0 6.5 5 2 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24477.1 - 1.6e-05 24.7 2.7 13 6.3 0.0 7.3 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.1 GAM24477.1 - 0.002 18.3 1.8 8.5 6.7 0.0 5.4 5 1 1 6 6 6 1 Ankyrin repeats (many copies) BCS1_N PF08740.6 GAM24478.1 - 1.6e-13 50.6 0.9 2.5e-13 50.0 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal FAD_binding_1 PF00667.15 GAM24479.1 - 1.3e-36 126.0 0.4 4.1e-36 124.4 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Oxidored-like PF09791.4 GAM24479.1 - 6.6e-14 51.0 6.0 8.6e-14 50.7 2.1 2.3 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.16 GAM24479.1 - 3.3e-13 50.1 1.9 3e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAM24479.1 - 0.007 16.2 1.2 0.035 13.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SNF5 PF04855.7 GAM24479.1 - 0.049 13.1 5.9 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 CAP PF00188.21 GAM24480.1 - 2.3e-11 44.2 1.5 2.3e-11 44.2 1.1 2.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.21 GAM24481.1 - 8.5e-08 32.7 0.2 3.6e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Rifin_STEVOR PF02009.11 GAM24481.1 - 0.014 15.0 2.4 0.018 14.6 1.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family FAM196 PF15265.1 GAM24481.1 - 9.2 5.3 16.1 13 4.9 11.2 1.1 1 0 0 1 1 1 0 FAM196 family Allantoicase PF03561.10 GAM24482.1 - 2.1e-103 342.2 0.0 9e-55 184.3 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 GAM24482.1 - 0.014 15.2 0.4 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 F5/8 type C domain Rhomboid PF01694.17 GAM24483.1 - 5.4e-40 136.7 15.3 5.4e-40 136.7 10.6 1.6 2 0 0 2 2 2 1 Rhomboid family Ribosomal_L6 PF00347.18 GAM24484.1 - 3.9e-23 81.7 7.0 3.8e-13 49.7 1.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 DUF1108 PF06531.6 GAM24484.1 - 0.037 14.1 2.6 1.8 8.7 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1108) ADK PF00406.17 GAM24485.1 - 2.7e-46 157.1 0.0 3.9e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAM24485.1 - 5.9e-13 48.2 0.1 1.8e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 GAM24485.1 - 5.6e-09 36.0 0.0 4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM24485.1 - 1.7e-08 35.3 0.0 2.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM24485.1 - 6.7e-08 32.9 0.0 1.8e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Neisseria_PilC PF05567.6 GAM24485.1 - 0.03 13.3 1.3 0.046 12.7 0.9 1.2 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Zeta_toxin PF06414.7 GAM24485.1 - 0.035 13.2 2.6 0.046 12.8 0.1 2.2 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 GAM24485.1 - 0.29 11.0 2.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 GAM24485.1 - 0.41 9.9 6.8 1.3 8.3 0.0 3.0 4 0 0 4 4 4 0 Thymidylate kinase SOXp PF12336.3 GAM24485.1 - 1.4 9.6 6.3 0.78 10.3 2.6 1.8 2 0 0 2 2 2 0 SOX transcription factor BAF1_ABF1 PF04684.8 GAM24485.1 - 2.5 6.8 14.2 3.3 6.4 9.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TraB PF01963.12 GAM24486.1 - 1.8e-09 37.4 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 TraB family TraB PF01963.12 GAM24487.1 - 2.7e-09 36.8 0.0 2.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 TraB family DUF399 PF04187.8 GAM24487.1 - 0.03 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 RRM_1 PF00076.17 GAM24488.1 - 1.7e-14 53.1 0.0 4.8e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM24488.1 - 4.9e-14 52.0 0.1 2.2e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM24488.1 - 9.8e-12 44.5 0.0 2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abi PF02517.11 GAM24489.1 - 1.4e-17 63.6 6.3 1.4e-17 63.6 4.4 2.2 2 0 0 2 2 2 1 CAAX protease self-immunity DUF2157 PF09925.4 GAM24489.1 - 0.00027 20.5 0.6 0.00027 20.5 0.4 2.2 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) BAF1_ABF1 PF04684.8 GAM24489.1 - 0.035 12.9 21.3 0.046 12.5 14.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 GAM24489.1 - 0.056 12.9 14.7 0.077 12.4 10.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPCC PF08058.6 GAM24489.1 - 0.069 13.0 9.6 0.097 12.5 3.0 3.0 2 1 0 2 2 2 0 Nuclear pore complex component Pox_Ag35 PF03286.9 GAM24489.1 - 0.4 10.1 16.2 0.61 9.5 11.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Dicty_REP PF05086.7 GAM24489.1 - 0.5 8.0 13.8 0.64 7.6 9.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.3 GAM24489.1 - 0.58 8.6 9.0 0.79 8.2 6.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.6 GAM24489.1 - 1.1 8.3 4.5 1.8 7.6 3.2 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Suf PF05843.9 GAM24489.1 - 1.3 8.6 14.2 2.1 7.9 9.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.8 GAM24489.1 - 2.8 7.3 11.7 4.2 6.8 8.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 GAM24489.1 - 3.4 7.4 10.1 5 6.9 7.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.1 GAM24489.1 - 4.3 6.9 13.8 6.6 6.3 9.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Ycf1 PF05758.7 GAM24489.1 - 4.6 4.8 14.0 1.3 6.6 7.5 1.6 2 0 0 2 2 2 0 Ycf1 DUF4557 PF15101.1 GAM24489.1 - 5.4 6.7 17.4 9.6 5.9 12.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TFIIA PF03153.8 GAM24489.1 - 5.6 6.7 26.0 6.9 6.4 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.3 GAM24489.1 - 7.4 5.1 17.3 10 4.7 12.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Piwi PF02171.12 GAM24490.1 - 1.6e-76 257.1 0.2 2.6e-76 256.4 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 GAM24490.1 - 1.1e-24 86.2 0.8 2.4e-24 85.1 0.6 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 GAM24490.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) Aldo_ket_red PF00248.16 GAM24491.1 - 1.2e-59 201.5 0.0 1.5e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family YqhG PF11079.3 GAM24491.1 - 0.0041 15.9 0.1 0.0058 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein YqhG of unknown function Pkinase PF00069.20 GAM24492.1 - 1.7e-44 151.9 0.0 3.7e-17 62.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24492.1 - 4.6e-23 81.6 0.0 6.7e-08 31.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 GAM24492.1 - 0.0026 16.8 0.0 0.0061 15.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIC3 PF15361.1 GAM24492.1 - 0.018 15.3 0.8 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Glypican PF01153.14 GAM24492.1 - 0.56 8.7 2.7 0.54 8.8 1.1 1.4 1 1 0 1 1 1 0 Glypican SGT1 PF07093.6 GAM24492.1 - 0.59 8.4 14.4 0.92 7.8 10.0 1.2 1 0 0 1 1 1 0 SGT1 protein DUF4611 PF15387.1 GAM24492.1 - 4.9 7.3 15.7 8.7 6.5 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.7 GAM24492.1 - 5.4 6.6 20.2 3.4 7.2 6.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Metallophos PF00149.23 GAM24494.1 - 2e-10 40.4 0.6 7e-10 38.6 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM24494.1 - 2.8e-05 24.0 0.0 3.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HD_5 PF13487.1 GAM24495.1 - 0.13 12.2 0.9 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 HD domain His_Phos_1 PF00300.17 GAM24496.1 - 1.2e-19 70.9 0.1 1.5e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C80 PF11713.3 GAM24496.1 - 0.021 14.6 0.2 0.032 14.0 0.2 1.3 1 0 0 1 1 1 0 Peptidase C80 family ApoL PF05461.6 GAM24497.1 - 9.6 5.3 7.3 11 5.1 5.1 1.1 1 0 0 1 1 1 0 Apolipoprotein L Cyclin_N PF00134.18 GAM24499.1 - 1.2e-41 141.2 4.9 2.8e-41 140.0 1.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM24499.1 - 1.6e-35 121.5 0.9 3.5e-35 120.4 0.6 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ank_2 PF12796.2 GAM24500.1 - 7.3e-56 186.4 23.9 2.3e-16 59.9 0.2 5.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM24500.1 - 4.7e-52 171.3 22.0 2.8e-08 33.1 0.1 9.6 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.1 GAM24500.1 - 5.9e-44 147.1 15.1 2.5e-09 37.0 0.0 6.4 3 1 3 6 6 6 6 Ankyrin repeats (many copies) SIR2 PF02146.12 GAM24500.1 - 3.1e-42 144.3 0.0 8.6e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 Sir2 family Ank_3 PF13606.1 GAM24500.1 - 4.3e-38 125.5 14.1 2.2e-05 24.2 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAM24500.1 - 2.4e-36 123.4 17.6 4.4e-08 33.4 0.1 8.4 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Glyco_hydro_16 PF00722.16 GAM24501.1 - 8.1e-48 162.1 0.5 2.9e-29 101.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAM24501.1 - 1.1e-18 66.6 8.4 2.7e-06 25.8 0.3 4.1 3 1 1 4 4 4 4 Beta-glucan synthesis-associated protein (SKN1) Ank_2 PF12796.2 GAM24502.1 - 2.8e-29 101.2 14.5 2.7e-07 30.8 0.5 7.3 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM24502.1 - 1.6e-24 85.8 15.9 3.6e-06 27.3 0.0 10.3 10 1 0 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM24502.1 - 1.6e-24 85.3 16.6 0.001 19.2 0.1 12.3 7 3 7 14 14 14 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24502.1 - 2e-16 58.4 18.4 0.12 12.7 0.0 13.3 12 3 4 16 16 16 4 Ankyrin repeat Ank PF00023.25 GAM24502.1 - 9.2e-13 47.3 19.7 0.58 10.0 0.0 12.1 11 3 3 14 14 14 4 Ankyrin repeat Rbsn PF11464.3 GAM24502.1 - 0.13 11.8 0.3 21 4.7 0.0 3.8 4 0 0 4 4 4 0 Rabenosyn Rab binding domain FNIP PF05725.7 GAM24503.1 - 1.4e-56 188.2 0.9 2.2e-12 46.7 0.0 10.3 6 2 7 13 13 13 11 FNIP Repeat LRR_5 PF13306.1 GAM24503.1 - 0.0094 15.6 0.0 0.07 12.8 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) MFS_2 PF13347.1 GAM24504.1 - 3.6e-96 322.1 33.2 4.4e-96 321.9 23.0 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 GAM24504.1 - 6.6e-20 71.1 46.7 2.6e-15 55.9 19.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Lectin_legB PF00139.14 GAM24505.1 - 8.3e-24 84.2 0.3 1.3e-23 83.6 0.2 1.2 1 0 0 1 1 1 1 Legume lectin domain zf-CCCH PF00642.19 GAM24506.1 - 4.9e-11 42.0 12.6 7.1e-07 28.7 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 GAM24506.1 - 0.00018 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM24506.1 - 0.00022 20.8 0.0 0.0024 17.4 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM24506.1 - 0.0036 17.2 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM24506.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Mito_carr PF00153.22 GAM24507.1 - 2.6e-57 190.5 3.3 3.5e-19 68.3 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein ADIP PF11559.3 GAM24508.1 - 6.2e-05 22.9 15.7 7.6e-05 22.6 10.9 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4201 PF13870.1 GAM24508.1 - 0.00023 20.6 10.4 0.0003 20.2 7.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) TSC22 PF01166.13 GAM24508.1 - 0.0025 17.7 8.4 0.054 13.4 0.2 2.8 1 1 2 3 3 3 1 TSC-22/dip/bun family IncA PF04156.9 GAM24508.1 - 0.0074 15.9 11.8 0.01 15.4 8.2 1.2 1 0 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 GAM24508.1 - 0.014 15.2 10.5 0.018 14.9 7.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 GAM24508.1 - 0.02 14.3 18.0 0.2 11.1 3.8 3.0 1 1 2 3 3 3 0 Septum formation initiator APG6 PF04111.7 GAM24508.1 - 0.028 13.4 12.4 0.031 13.3 8.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 GAM24508.1 - 0.034 13.8 11.7 0.043 13.4 8.1 1.1 1 0 0 1 1 1 0 Mnd1 family TMF_TATA_bd PF12325.3 GAM24508.1 - 0.042 13.5 12.0 2.3 7.9 8.4 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 GAM24508.1 - 0.043 13.0 2.5 0.051 12.7 1.7 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Mod_r PF07200.8 GAM24508.1 - 0.047 13.6 12.5 0.095 12.6 8.6 1.6 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.2 GAM24508.1 - 0.049 13.4 14.8 0.19 11.5 9.1 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF812 PF05667.6 GAM24508.1 - 0.055 11.9 16.5 0.21 10.0 11.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 GAM24508.1 - 0.07 13.4 10.7 0.65 10.3 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 GAM24508.1 - 0.078 12.9 12.0 0.31 11.0 1.0 3.1 2 1 1 3 3 3 0 bZIP transcription factor Phage_GP20 PF06810.6 GAM24508.1 - 0.096 12.1 19.1 0.43 10.0 9.4 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 Macoilin PF09726.4 GAM24508.1 - 0.11 10.7 7.3 0.13 10.5 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Med7 PF05983.6 GAM24508.1 - 0.11 12.2 5.0 0.15 11.8 3.5 1.2 1 0 0 1 1 1 0 MED7 protein PspA_IM30 PF04012.7 GAM24508.1 - 0.14 11.4 10.7 0.39 10.0 5.3 2.0 1 1 1 2 2 2 0 PspA/IM30 family BLOC1_2 PF10046.4 GAM24508.1 - 0.16 12.1 12.9 0.09 12.9 7.1 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spore_GerAC PF05504.6 GAM24508.1 - 0.17 11.6 7.8 0.2 11.3 5.4 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Fib_alpha PF08702.5 GAM24508.1 - 0.17 11.9 13.5 0.27 11.3 9.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.4 GAM24508.1 - 0.18 11.3 7.8 1.4 8.5 4.8 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) V_ATPase_I PF01496.14 GAM24508.1 - 0.19 9.5 9.5 0.21 9.4 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 GAM24508.1 - 0.19 10.1 0.5 0.21 9.9 0.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kinesin-relat_1 PF12711.2 GAM24508.1 - 0.2 12.0 9.6 3.7 8.0 0.2 3.0 1 1 2 3 3 3 0 Kinesin motor Lebercilin PF15619.1 GAM24508.1 - 0.2 11.0 14.9 0.4 10.0 10.2 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Rep_4 PF05797.6 GAM24508.1 - 0.2 10.3 8.2 0.24 10.0 5.7 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) TMF_DNA_bd PF12329.3 GAM24508.1 - 0.24 11.2 17.9 0.19 11.5 8.2 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 GAM24508.1 - 0.26 11.0 6.1 1.8 8.3 0.3 3.0 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF641 PF04859.7 GAM24508.1 - 0.29 10.9 12.0 1.6 8.4 0.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tup_N PF08581.5 GAM24508.1 - 0.5 10.5 12.2 0.11 12.7 3.3 2.3 1 1 1 2 2 2 0 Tup N-terminal Sigma70_ner PF04546.8 GAM24508.1 - 0.52 9.8 10.6 0.64 9.5 7.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RTBV_P46 PF06216.6 GAM24508.1 - 0.64 8.8 4.5 1.1 8.0 3.1 1.4 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF1676 PF07898.8 GAM24508.1 - 0.67 10.2 4.9 24 5.2 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) DUF506 PF04720.7 GAM24508.1 - 0.68 9.5 7.0 0.87 9.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF342 PF03961.8 GAM24508.1 - 0.72 8.2 10.1 0.85 7.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 GAM24508.1 - 0.74 10.1 13.8 5 7.4 9.6 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 GAM24508.1 - 0.9 10.0 11.4 0.2 12.0 2.4 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Striatin PF08232.7 GAM24508.1 - 1 9.6 9.0 1.6 9.0 6.1 1.4 1 1 0 1 1 1 0 Striatin family Sterile PF03015.14 GAM24508.1 - 1.1 9.5 3.9 3.3 8.0 0.4 2.1 1 1 1 2 2 2 0 Male sterility protein ACCA PF03255.9 GAM24508.1 - 1.1 8.7 10.8 2 7.9 4.5 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Atg14 PF10186.4 GAM24508.1 - 1.3 7.8 11.3 1.6 7.6 7.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 GAM24508.1 - 1.8 8.1 13.3 0.46 10.0 6.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.3 GAM24508.1 - 2 7.6 14.1 3.3 6.9 9.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3782 PF12644.2 GAM24508.1 - 2.2 8.1 5.0 22 4.9 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) DUF904 PF06005.7 GAM24508.1 - 2.3 8.5 14.7 3.3 8.0 7.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) LysM PF01476.15 GAM24508.1 - 2.3 8.1 4.4 10 6.0 0.3 2.4 1 1 1 2 2 2 0 LysM domain DUF3573 PF12097.3 GAM24508.1 - 2.4 6.6 7.0 3.3 6.2 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Seryl_tRNA_N PF02403.17 GAM24508.1 - 2.6 8.1 15.8 0.94 9.5 2.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 GAM24508.1 - 3.3 7.5 9.6 2.6 7.8 5.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.13 GAM24508.1 - 3.9 6.4 8.4 5.1 6.0 5.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RF-1 PF00472.15 GAM24508.1 - 4.3 7.1 10.1 1.1 9.1 2.1 2.1 1 1 1 2 2 2 0 RF-1 domain FlaC_arch PF05377.6 GAM24508.1 - 4.8 7.1 12.9 28 4.6 0.9 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Bap31 PF05529.7 GAM24508.1 - 5.2 6.4 16.3 2.9e+02 0.7 11.3 2.1 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Pox_RNA_Pol_19 PF05320.7 GAM24508.1 - 5.7 6.6 12.6 3.2 7.4 7.5 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TMPIT PF07851.8 GAM24508.1 - 7.3 5.5 9.0 9 5.2 6.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Uso1_p115_C PF04871.8 GAM24508.1 - 7.9 6.4 17.3 28 4.6 12.0 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Imm46 PF15585.1 GAM24508.1 - 8.3 6.4 6.9 8.2 6.4 4.0 1.6 1 1 0 1 1 1 0 Immunity protein 46 YebO PF13974.1 GAM24508.1 - 9.2 6.1 11.5 3.8 7.3 6.0 1.9 1 1 1 2 2 2 0 YebO-like protein Rhodanese PF00581.15 GAM24509.1 - 2.6e-07 30.9 0.0 4.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zf-C3H1 PF10650.4 GAM24510.1 - 2.5e-05 23.6 0.4 4.3e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain DUF3439 PF11921.3 GAM24510.1 - 2.4 7.9 18.2 0.35 10.6 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Vps51 PF08700.6 GAM24512.1 - 3.3e-13 49.2 2.2 3.3e-13 49.2 1.5 2.8 2 0 0 2 2 2 1 Vps51/Vps67 E2F_TDP PF02319.15 GAM24513.1 - 1.1e-09 37.6 5.4 2.1e-05 23.9 0.1 2.8 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain YppG PF14179.1 GAM24513.1 - 6.3 7.4 28.1 2.2 8.8 7.9 3.8 4 0 0 4 4 4 0 YppG-like protein ABA_GPCR PF12430.3 GAM24514.1 - 3e-53 179.8 9.8 3e-53 179.8 6.8 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 GAM24514.1 - 2.1e-22 78.9 0.1 7.7e-22 77.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Ribosomal_S7e PF01251.13 GAM24514.1 - 0.082 12.3 0.2 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein S7e fn3 PF00041.16 GAM24515.1 - 1.6e-09 37.7 13.1 9.5e-09 35.2 2.1 3.3 3 0 0 3 3 3 2 Fibronectin type III domain DUF824 PF05688.6 GAM24515.1 - 0.53 9.9 2.8 19 5.0 0.1 3.2 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) Rhodanese PF00581.15 GAM24516.1 - 2.8e-13 50.1 0.0 6.8e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF479 PF04336.7 GAM24518.1 - 0.0018 18.3 0.5 0.073 13.1 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF479 TrbM PF07424.6 GAM24518.1 - 0.06 13.3 0.6 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 TrbM DUF2910 PF11139.3 GAM24518.1 - 0.067 12.3 0.3 0.14 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Peroxin-3 PF04882.7 GAM24519.1 - 3.9e-34 118.0 8.9 3.3e-31 108.4 1.8 3.1 1 1 1 2 2 2 2 Peroxin-3 PH_3 PF14593.1 GAM24520.1 - 2.5e-15 56.2 1.0 6.6e-15 54.8 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM24520.1 - 1.4e-05 25.3 0.2 1.4e-05 25.3 0.2 3.2 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 GAM24520.1 - 5.5e-05 23.3 0.1 5.5e-05 23.3 0.1 2.8 3 1 0 3 3 3 1 PH domain Lip_prot_lig_C PF10437.4 GAM24520.1 - 0.0073 15.9 0.1 0.02 14.5 0.1 1.7 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus PH_6 PF15406.1 GAM24520.1 - 0.055 13.5 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Mre11_DNA_bind PF04152.9 GAM24521.1 - 2.3e-38 131.7 0.0 8.4e-38 129.9 0.0 2.1 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 GAM24521.1 - 9.8e-27 93.6 3.5 1.7e-26 92.8 2.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M18 PF02127.10 GAM24522.1 - 1.4e-146 488.3 0.0 6.1e-146 486.3 0.0 1.8 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 GAM24522.1 - 6.7e-06 25.0 0.1 0.00096 18.0 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase zf-UBR PF02207.15 GAM24523.1 - 5.8e-08 32.3 12.6 5.8e-08 32.3 8.7 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 GAM24523.1 - 0.00053 19.7 1.0 0.00053 19.7 0.7 4.3 5 0 0 5 5 5 1 Ring finger domain DUF4632 PF15451.1 GAM24523.1 - 0.2 11.6 0.0 0.7 9.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF3439 PF11921.3 GAM24523.1 - 6.6 6.5 29.4 1.1 8.9 9.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Methyltransf_23 PF13489.1 GAM24524.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM24524.1 - 9.1e-08 32.6 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM24524.1 - 4.7e-06 27.0 1.1 8.3e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM24524.1 - 6.5e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM24524.1 - 0.00011 21.8 0.0 0.00035 20.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM24524.1 - 0.0022 18.4 0.0 0.0058 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM24524.1 - 0.0022 18.2 0.0 0.0066 16.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain KIF1B PF12423.3 GAM24524.1 - 0.014 15.4 0.0 0.057 13.4 0.0 2.0 2 0 0 2 2 2 0 Kinesin protein 1B Methyltransf_PK PF05891.7 GAM24524.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TehB PF03848.9 GAM24524.1 - 0.078 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Mto2_bdg PF12808.2 GAM24525.1 - 0.025 14.6 5.7 0.025 14.6 4.0 2.2 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region IncA PF04156.9 GAM24525.1 - 0.11 12.1 8.2 0.25 10.9 5.7 1.6 1 0 0 1 1 1 0 IncA protein CRT-like PF08627.5 GAM24526.1 - 4e-38 130.2 0.4 4e-38 130.2 0.3 2.3 3 0 0 3 3 3 1 CRT-like DUF914 PF06027.7 GAM24526.1 - 2.3e-10 39.8 10.8 8.8e-09 34.6 2.8 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 GAM24526.1 - 8.4e-05 22.2 19.2 0.0099 15.5 3.9 3.1 2 2 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 GAM24526.1 - 0.0014 18.6 9.9 0.0014 18.6 6.9 3.9 3 1 0 3 3 3 1 EamA-like transporter family DUF2721 PF11026.3 GAM24526.1 - 0.09 12.4 2.6 0.13 11.9 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) EmrE PF13536.1 GAM24526.1 - 3.5 7.8 24.9 0.27 11.4 5.4 3.0 3 1 0 3 3 3 0 Multidrug resistance efflux transporter TIG PF01833.19 GAM24527.1 - 0.003 17.5 62.3 0.0072 16.2 1.9 8.6 6 3 3 9 9 9 6 IPT/TIG domain GTP_EFTU PF00009.22 GAM24528.1 - 2.6e-23 82.4 0.2 1.6e-22 79.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM24528.1 - 9.3e-16 57.8 0.2 5.6e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM24528.1 - 5.2e-05 23.2 2.0 5.2e-05 23.2 1.4 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 GAM24528.1 - 0.008 15.7 1.1 0.018 14.6 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA PF00004.24 GAM24528.1 - 0.068 13.3 2.4 10 6.3 0.0 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 GAM24528.1 - 0.12 11.9 0.1 0.44 10.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain RhoGEF PF00621.15 GAM24529.1 - 1.9e-54 184.2 3.7 1.9e-54 184.2 2.5 3.3 3 1 0 3 3 3 1 RhoGEF domain IQ PF00612.22 GAM24529.1 - 4e-05 22.8 0.5 0.00012 21.4 0.4 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.24 GAM24529.1 - 0.01 16.0 0.0 0.01 16.0 0.0 3.0 4 0 0 4 4 4 1 PH domain FSH1 PF03959.8 GAM24530.1 - 1.3e-47 161.9 0.1 2.5e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF924 PF06041.6 GAM24530.1 - 1e-39 136.2 0.1 2.6e-39 134.9 0.1 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) LRR_6 PF13516.1 GAM24530.1 - 5.7e-10 38.2 20.6 0.017 15.1 0.1 8.5 9 0 0 9 9 9 4 Leucine Rich repeat Abhydrolase_5 PF12695.2 GAM24530.1 - 8e-07 28.9 0.1 1.9e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM24530.1 - 1.2e-05 25.3 0.0 0.0009 19.1 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family LRR_4 PF12799.2 GAM24530.1 - 0.067 12.8 11.7 1.1 8.9 0.0 4.7 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) SpoU_sub_bind PF08032.7 GAM24530.1 - 0.11 12.6 0.0 22 5.3 0.0 3.4 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding LRR_7 PF13504.1 GAM24530.1 - 0.14 12.4 3.5 32 5.3 0.1 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 GAM24530.1 - 0.76 10.0 8.9 42 4.7 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat TPR_11 PF13414.1 GAM24531.1 - 2.9e-19 68.4 13.9 5.8e-10 38.6 0.7 5.0 3 2 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM24531.1 - 2.1e-16 58.7 16.8 1.7e-07 30.5 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24531.1 - 6.5e-14 50.6 15.6 0.00022 20.8 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24531.1 - 1.3e-11 44.8 6.9 0.0086 16.7 2.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24531.1 - 5.4e-11 41.4 8.1 0.00046 19.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24531.1 - 6.6e-10 38.7 7.6 0.0014 19.1 0.6 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24531.1 - 4.4e-09 36.1 11.0 5.4e-05 23.0 0.4 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24531.1 - 1.8e-08 33.9 4.9 0.00013 21.8 0.0 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM24531.1 - 1.8e-07 30.9 8.0 0.00026 20.7 0.0 4.5 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24531.1 - 2.4e-05 24.6 10.4 0.13 12.6 2.2 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM24531.1 - 0.00059 20.1 15.5 0.0096 16.3 0.0 6.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24531.1 - 0.0032 17.1 7.9 0.51 10.2 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM24531.1 - 0.025 14.7 10.2 0.18 11.9 0.1 3.6 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3136 PF11334.3 GAM24531.1 - 0.081 12.3 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) LAM_C PF12544.3 GAM24531.1 - 0.85 9.6 3.5 2.9 7.9 0.7 2.3 2 0 0 2 2 2 0 Lysine-2,3-aminomutase rve_2 PF13333.1 GAM24531.1 - 1.6 8.8 4.7 4.6 7.3 0.1 2.9 2 1 1 3 3 3 0 Integrase core domain HLH PF00010.21 GAM24532.1 - 0.0028 17.2 0.3 0.011 15.4 0.2 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Macoilin PF09726.4 GAM24532.1 - 4.6 5.4 10.3 5.6 5.1 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 GAM24533.1 - 7.3e-30 103.8 29.6 1.4e-28 99.6 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM24533.1 - 2.9e-17 62.1 14.7 2.9e-17 62.1 10.2 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 GAM24533.1 - 1.6e-07 30.2 24.0 1.4e-05 23.8 7.5 2.4 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 GAM24533.1 - 0.0043 15.2 4.9 0.011 13.8 3.4 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector PI3_PI4_kinase PF00454.22 GAM24534.1 - 4e-39 134.4 0.1 2.6e-38 131.7 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAM24534.1 - 9.1e-24 83.6 0.1 2.5e-23 82.2 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pyr_redox_2 PF07992.9 GAM24535.1 - 3.1e-27 95.7 0.0 4.5e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM24535.1 - 1.9e-11 44.1 0.0 2.9e-09 37.2 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM24535.1 - 1.9e-05 24.8 0.0 0.015 15.3 0.0 3.4 2 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM24535.1 - 0.0093 14.9 0.0 0.049 12.5 0.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase DRIM PF07539.7 GAM24535.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Down-regulated in metastasis Ras PF00071.17 GAM24536.1 - 1.3e-14 53.9 1.0 2.6e-06 26.9 0.0 2.7 3 0 0 3 3 3 2 Ras family Miro PF08477.8 GAM24536.1 - 3.2e-12 46.9 0.6 3.2e-12 46.9 0.4 2.9 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM24536.1 - 1.3e-07 31.0 0.1 0.0081 15.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 GAM24536.1 - 0.00074 19.6 0.9 0.026 14.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM24536.1 - 0.3 11.0 5.1 0.17 11.8 0.4 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF3306 PF11748.3 GAM24536.1 - 1.9 9.1 9.8 7.6 7.2 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) SelP_N PF04592.9 GAM24536.1 - 4.4 6.6 28.6 0.085 12.2 8.2 3.5 3 0 0 3 3 3 0 Selenoprotein P, N terminal region DUF948 PF06103.6 GAM24537.1 - 0.075 12.8 0.5 0.075 12.8 0.3 5.3 2 1 2 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF552 PF04472.7 GAM24537.1 - 0.1 12.5 0.1 0.45 10.4 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Filament PF00038.16 GAM24537.1 - 0.34 10.3 46.1 1.1 8.6 6.7 3.8 2 2 0 3 3 3 0 Intermediate filament protein ApoO PF09769.4 GAM24537.1 - 2.2 7.9 7.6 0.51 10.0 0.1 2.8 2 1 1 3 3 3 0 Apolipoprotein O Reo_sigmaC PF04582.7 GAM24537.1 - 2.2 7.3 22.4 2.2 7.3 1.5 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Arif-1 PF06770.6 GAM24538.1 - 0.038 13.3 1.0 0.054 12.8 0.7 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Tetraspannin PF00335.15 GAM24538.1 - 6.6 5.9 11.8 1.1 8.5 4.7 1.9 1 1 1 2 2 2 0 Tetraspanin family FNIP PF05725.7 GAM24539.1 - 1.7e-47 159.1 23.3 8.1e-12 44.9 0.4 7.1 2 1 0 6 6 6 5 FNIP Repeat DUF1769 PF08588.5 GAM24539.1 - 0.0015 18.3 6.7 8.8 6.3 0.0 6.0 2 1 4 7 7 7 2 Protein of unknown function (DUF1769) DUF605 PF04652.11 GAM24539.1 - 3 7.1 13.7 3.9 6.7 9.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 GAM24539.1 - 4.3 6.7 15.0 6.2 6.2 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PIG-L PF02585.12 GAM24540.1 - 2.7e-29 102.2 0.0 3.8e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF364 PF04016.7 GAM24540.1 - 0.14 11.5 0.0 0.46 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF364) zf-C3HC4_2 PF13923.1 GAM24541.1 - 4.1e-10 39.5 9.3 8.4e-10 38.5 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM24541.1 - 2e-09 36.9 5.9 3.3e-09 36.2 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM24541.1 - 1.1e-07 31.3 6.8 2.4e-07 30.3 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM24541.1 - 2.7e-07 30.3 8.1 5.7e-07 29.2 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM24541.1 - 1.1e-06 28.2 6.5 2.4e-06 27.1 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM24541.1 - 0.0009 18.9 1.8 0.0009 18.9 1.2 2.8 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 GAM24541.1 - 0.0017 17.8 13.5 0.0033 16.9 7.3 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 GAM24541.1 - 0.012 15.4 9.2 0.028 14.2 6.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 GAM24541.1 - 0.065 12.7 6.2 0.16 11.4 4.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 GAM24541.1 - 0.075 12.8 3.8 0.21 11.4 2.6 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 GAM24541.1 - 0.17 11.3 0.8 1 8.8 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.1 GAM24541.1 - 0.18 11.4 5.9 1 8.9 4.5 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 GAM24541.1 - 0.32 11.1 3.3 1.2 9.3 2.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 GAM24541.1 - 1.5 8.3 9.0 9 5.8 6.2 2.2 1 1 1 2 2 2 0 P-11 zinc finger DUF2547 PF10818.3 GAM24541.1 - 4.5 7.9 12.9 1.3 9.6 5.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2547) CWC25 PF12542.3 GAM24541.1 - 6.7 7.2 15.1 0.083 13.3 4.0 2.6 3 0 0 3 3 3 0 Pre-mRNA splicing factor Pkinase PF00069.20 GAM24546.1 - 6.2e-69 232.0 0.0 1.6e-68 230.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24546.1 - 2.3e-55 187.4 0.0 4.9e-55 186.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24546.1 - 0.00014 20.9 0.0 0.00062 18.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Clat_adaptor_s PF01217.15 GAM24547.1 - 3.9e-54 182.2 2.3 4.5e-54 182.0 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Plasmid_stabil PF05016.9 GAM24547.1 - 0.044 14.1 0.1 0.098 13.0 0.0 1.5 2 0 0 2 2 2 0 Plasmid stabilisation system protein DUF1204 PF06721.6 GAM24547.1 - 0.055 12.7 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) polyprenyl_synt PF00348.12 GAM24548.1 - 9.4e-67 224.5 0.0 1.4e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1564 PF07600.6 GAM24548.1 - 0.081 12.2 0.1 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) Metallophos PF00149.23 GAM24549.1 - 7.7e-41 139.6 0.2 1.2e-40 139.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Polyketide_cyc2 PF10604.4 GAM24550.1 - 4.2e-10 39.9 0.1 5.2e-10 39.6 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 GAM24550.1 - 0.079 12.9 0.1 0.1 12.5 0.1 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport ABC_membrane PF00664.18 GAM24551.1 - 2e-50 171.7 40.5 9.8e-29 100.6 10.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM24551.1 - 3.9e-49 166.4 0.0 5.2e-29 101.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM24551.1 - 1.7e-11 43.8 0.0 8.6e-05 21.8 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM24551.1 - 6.3e-10 39.4 0.2 0.15 11.9 0.0 5.4 3 2 2 5 5 5 2 AAA domain DUF258 PF03193.11 GAM24551.1 - 0.00014 21.0 0.4 0.026 13.7 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM24551.1 - 0.00027 20.4 1.5 0.73 9.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAM24551.1 - 0.00032 21.1 0.1 0.17 12.3 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 GAM24551.1 - 0.0007 19.5 0.6 1.7 8.6 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_25 PF13481.1 GAM24551.1 - 0.0034 16.7 0.0 0.49 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM24551.1 - 0.0035 17.6 0.1 0.54 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 GAM24551.1 - 0.0062 15.4 0.2 1.5 7.6 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 GAM24551.1 - 0.01 16.6 0.9 1.3 9.8 0.4 3.0 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 GAM24551.1 - 0.02 14.3 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF87 PF01935.12 GAM24551.1 - 0.05 13.4 0.1 0.05 13.4 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 GAM24551.1 - 0.06 12.8 0.5 9.9 5.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 GAM24551.1 - 0.13 12.4 1.6 4.6 7.3 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAM24551.1 - 0.13 12.5 12.3 0.19 12.0 0.0 3.7 3 1 1 4 4 4 0 AAA domain ArgK PF03308.11 GAM24551.1 - 0.16 10.7 0.7 8.5 5.0 0.1 2.3 2 0 0 2 2 2 0 ArgK protein PAP_assoc PF03828.14 GAM24552.1 - 1.6e-09 37.5 0.2 4.6e-09 36.0 0.2 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAM24552.1 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain ABC2_membrane_3 PF12698.2 GAM24552.1 - 2.3 7.1 13.0 6.1 5.7 9.0 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein TIG PF01833.19 GAM24553.1 - 7.6e-06 25.8 3.5 2.5e-05 24.1 1.2 2.7 2 0 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.8 GAM24553.1 - 0.00044 20.3 13.2 0.0012 18.9 9.1 1.8 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 GAM24553.1 - 0.0088 15.9 6.1 0.0088 15.9 4.2 1.9 2 0 0 2 2 2 1 Laminin EGF-like (Domains III and V) Nucleoporin_N PF08801.6 GAM24554.1 - 5.2e-48 163.8 1.7 5.2e-48 163.8 1.1 1.7 2 0 0 2 2 2 1 Nup133 N terminal like PQQ_3 PF13570.1 GAM24554.1 - 0.12 12.6 0.2 0.39 11.0 0.1 1.8 1 0 0 1 1 1 0 PQQ-like domain IBR PF01485.16 GAM24555.1 - 6.5e-19 67.5 53.1 7.4e-15 54.5 4.2 4.6 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 GAM24555.1 - 4.1e-07 29.9 5.7 4.1e-07 29.9 3.9 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM24555.1 - 9.6e-07 28.5 2.0 9.6e-07 28.5 1.4 4.3 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 GAM24555.1 - 3.2e-05 23.4 2.9 3.2e-05 23.4 2.0 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF382 PF04037.8 GAM24556.1 - 3.4e-53 178.8 0.4 3.4e-53 178.8 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 GAM24556.1 - 2.9e-23 80.9 4.8 6.4e-23 79.8 3.3 1.6 1 0 0 1 1 1 1 PSP Pex16 PF08610.5 GAM24556.1 - 0.15 11.0 0.1 0.15 11.0 0.1 3.6 4 0 0 4 4 4 0 Peroxisomal membrane protein (Pex16) DUF2152 PF10222.4 GAM24556.1 - 4.2 5.4 8.0 3.3 5.8 4.5 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2152) RabGAP-TBC PF00566.13 GAM24557.1 - 1.7e-23 83.2 8.2 2.3e-14 53.3 0.3 6.8 3 2 1 5 5 5 2 Rab-GTPase-TBC domain Pkinase PF00069.20 GAM24558.1 - 8.9e-72 241.3 0.0 1.4e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24558.1 - 4.7e-53 179.9 0.0 6.6e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24558.1 - 0.044 12.7 0.0 0.087 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like C2 PF00168.25 GAM24558.1 - 0.061 13.1 0.9 0.13 12.1 0.7 1.5 1 0 0 1 1 1 0 C2 domain DUF2457 PF10446.4 GAM24558.1 - 0.48 9.0 23.2 0.74 8.4 16.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RasGAP PF00616.14 GAM24559.1 - 1.1e-39 136.1 0.0 1.1e-39 136.1 0.0 3.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase DUF4083 PF13314.1 GAM24559.1 - 0.27 11.1 2.0 21 5.0 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Arf PF00025.16 GAM24560.1 - 7.9e-47 158.7 0.1 9.6e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM24560.1 - 2e-22 79.3 0.0 2.4e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAM24560.1 - 4.2e-12 45.6 0.0 5e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM24560.1 - 6.5e-12 45.9 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM24560.1 - 2.2e-10 40.0 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM24560.1 - 2e-09 37.4 0.0 3.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM24560.1 - 2.8e-09 36.1 0.1 4.9e-07 28.7 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 GAM24560.1 - 4.2e-06 26.3 0.0 0.00026 20.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAM24560.1 - 0.019 14.7 0.2 0.7 9.6 0.2 2.2 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 GAM24560.1 - 0.044 13.3 0.0 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 GAM24560.1 - 0.079 12.2 1.1 0.16 11.2 0.1 2.0 2 1 0 2 2 2 0 Ferrous iron transport protein B DNase_II PF03265.10 GAM24561.1 - 1.5e-70 237.7 4.6 2e-70 237.3 3.2 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II EGF_2 PF07974.8 GAM24562.1 - 0.0033 17.5 12.4 0.0076 16.3 8.6 1.6 1 0 0 1 1 1 1 EGF-like domain LRR_1 PF00560.28 GAM24562.1 - 1.8 8.8 5.3 39 4.8 0.2 5.5 3 1 0 3 3 3 0 Leucine Rich Repeat EGF PF00008.22 GAM24562.1 - 2 8.4 10.4 4.6 7.3 7.2 1.7 1 0 0 1 1 1 0 EGF-like domain Hydrolase_4 PF12146.3 GAM24563.1 - 1.1e-25 89.2 0.0 1.7e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 GAM24563.1 - 2.6e-21 76.5 0.0 3.9e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM24563.1 - 3.3e-19 69.0 0.0 5.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM24563.1 - 4.5e-08 32.9 0.2 2e-06 27.5 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 GAM24563.1 - 3.2e-06 26.7 0.0 0.76 9.1 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 GAM24563.1 - 9.1e-05 21.7 0.3 0.014 14.6 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.15 GAM24563.1 - 0.0001 22.6 0.0 0.00017 21.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 GAM24563.1 - 0.00037 20.0 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 GAM24563.1 - 0.00039 19.9 0.0 0.0013 18.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 GAM24563.1 - 0.0018 17.8 0.0 0.0037 16.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 GAM24563.1 - 0.016 13.7 0.0 0.14 10.5 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.8 GAM24563.1 - 0.018 14.6 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 GAM24563.1 - 0.036 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.13 GAM24563.1 - 0.099 12.0 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 GAM24563.1 - 0.19 10.0 0.2 20 3.3 0.0 2.8 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II CAF-1_p150 PF11600.3 GAM24564.1 - 0.014 14.7 36.9 0.021 14.2 8.4 3.6 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Methyltransf_23 PF13489.1 GAM24565.1 - 1e-28 100.0 0.1 2.3e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain zf-piccolo PF05715.8 GAM24565.1 - 0.0037 17.2 2.4 0.02 14.9 1.1 2.4 2 0 0 2 2 2 1 Piccolo Zn-finger Methyltransf_31 PF13847.1 GAM24565.1 - 0.022 14.3 0.2 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 GAM24565.1 - 0.037 14.5 0.8 0.44 11.0 0.0 3.0 3 2 1 4 4 4 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM24565.1 - 0.039 14.4 0.8 0.58 10.6 0.1 2.9 2 1 0 2 2 2 0 Methyltransferase domain DUF2387 PF09526.5 GAM24565.1 - 0.12 12.3 0.1 0.43 10.5 0.1 1.9 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) SSP160 PF06933.6 GAM24565.1 - 1.7 6.5 17.8 2.2 6.1 12.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribonuc_red_lgC PF02867.10 GAM24566.1 - 3.5e-213 709.0 0.0 4.7e-213 708.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 GAM24566.1 - 3.3e-21 74.8 0.0 8.9e-21 73.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 GAM24566.1 - 7e-16 58.4 0.1 2.4e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain FNIP PF05725.7 GAM24567.1 - 2.8e-65 216.0 37.8 1.4e-13 50.5 0.1 9.1 8 1 1 9 9 9 8 FNIP Repeat Ank_2 PF12796.2 GAM24570.1 - 3.8e-19 68.8 3.9 0.055 13.8 0.1 8.7 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24570.1 - 1.3e-05 25.0 18.5 27 5.3 0.0 12.9 16 0 0 16 16 16 1 Ankyrin repeat Ank_4 PF13637.1 GAM24570.1 - 5.7e-05 23.5 3.9 6.2 7.4 0.0 8.7 10 1 2 12 12 12 1 Ankyrin repeats (many copies) RNase_T PF00929.19 GAM24571.1 - 6.5e-09 36.2 0.1 1.9e-07 31.5 0.0 3.0 3 0 0 3 3 3 1 Exonuclease Sec20 PF03908.8 GAM24571.1 - 0.048 13.3 1.1 0.27 10.9 0.8 2.4 1 0 0 1 1 1 0 Sec20 DUF812 PF05667.6 GAM24571.1 - 0.053 12.0 6.2 0.19 10.2 4.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.16 GAM24571.1 - 0.1 12.5 4.7 0.11 12.4 1.2 2.5 1 1 1 2 2 2 0 bZIP transcription factor IncA PF04156.9 GAM24571.1 - 0.12 12.0 6.5 0.05 13.1 2.5 1.8 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 GAM24571.1 - 0.79 10.0 11.0 1.4 9.3 4.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3186 PF11382.3 GAM24571.1 - 1.7 7.7 3.7 3.3 6.7 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3186) DivIC PF04977.10 GAM24571.1 - 1.8 8.0 8.4 6 6.4 1.8 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 GAM24571.1 - 8.7 6.7 16.0 0.98 9.7 6.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Sec7 PF01369.15 GAM24574.1 - 3.9e-59 199.5 0.2 3.9e-59 199.5 0.1 2.3 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 GAM24574.1 - 0.00023 21.3 10.0 0.0006 19.9 0.1 3.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM24574.1 - 0.012 15.8 0.1 0.012 15.8 0.0 3.6 4 0 0 4 4 4 0 Pleckstrin homology domain UNC-50 PF05216.8 GAM24574.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 UNC-50 family HAD_2 PF13419.1 GAM24575.1 - 2.5e-15 57.1 0.2 2.9e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Motile_Sperm PF00635.21 GAM24575.1 - 0.045 13.3 0.2 0.9 9.2 0.0 2.6 3 0 0 3 3 3 0 MSP (Major sperm protein) domain NAPRTase PF04095.11 GAM24576.1 - 8.8e-27 93.9 0.0 2.3e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Dzip-like_N PF13815.1 GAM24577.1 - 0.3 10.8 3.3 0.37 10.6 0.6 2.3 3 0 0 3 3 3 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal UCH PF00443.24 GAM24578.1 - 9.7e-78 260.9 0.0 2.2e-77 259.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM24578.1 - 1.6e-12 47.5 0.0 5.9e-05 22.6 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 GAM24579.1 - 3.1e-18 65.9 0.9 7.5e-18 64.7 0.0 2.2 3 1 0 3 3 3 1 DUSP domain Kelch_6 PF13964.1 GAM24580.1 - 4.5e-14 51.9 2.9 0.00092 19.2 0.0 4.1 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM24580.1 - 2.6e-11 43.1 7.7 0.0024 17.6 0.1 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24580.1 - 7.3e-09 35.5 1.6 0.27 11.4 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24580.1 - 1.1e-06 28.0 5.2 0.021 14.3 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 GAM24580.1 - 0.00032 20.5 1.5 0.42 10.6 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 GAM24580.1 - 0.00044 19.9 0.6 5.4 6.9 0.0 3.8 3 0 0 3 3 3 2 Kelch motif DUF2383 PF09537.5 GAM24580.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Cullin_binding PF03556.10 GAM24581.1 - 5.3e-28 97.4 1.5 6.2e-28 97.2 0.5 1.5 2 0 0 2 2 2 1 Cullin binding HMA PF00403.21 GAM24582.1 - 8e-12 45.1 1.7 1.1e-11 44.7 1.2 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF1677 PF07911.8 GAM24582.1 - 0.043 14.0 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Mo25 PF08569.6 GAM24583.1 - 3e-128 427.5 19.7 3.4e-128 427.3 13.7 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 GAM24583.1 - 0.0095 16.2 0.0 0.086 13.1 0.0 2.4 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 GAM24583.1 - 0.14 12.2 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat DUF2937 PF11157.3 GAM24583.1 - 0.23 10.7 1.1 2.3 7.5 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) TGT PF01702.13 GAM24583.1 - 0.41 9.9 2.8 4.1 6.6 0.0 2.5 2 1 1 3 3 3 0 Queuine tRNA-ribosyltransferase VPS9 PF02204.13 GAM24584.1 - 3.6e-29 100.8 0.1 1.4e-28 98.9 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.19 GAM24584.1 - 3.2e-19 68.7 4.2 1.4e-18 66.7 0.4 3.0 2 1 0 2 2 2 1 PX domain Ras PF00071.17 GAM24584.1 - 5.6e-10 38.8 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24584.1 - 0.0016 18.9 0.1 0.0065 16.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein RED_N PF07808.8 GAM24585.1 - 1.5e-18 66.9 15.4 9.8e-18 64.2 3.1 4.3 2 1 2 4 4 4 2 RED-like protein N-terminal region Cloacin_immun PF03513.9 GAM24585.1 - 0.032 14.2 0.0 0.097 12.7 0.0 1.9 1 0 0 1 1 1 0 Cloacin immunity protein GST_C_3 PF14497.1 GAM24585.1 - 0.087 13.3 0.2 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ras PF00071.17 GAM24586.1 - 1.8e-50 170.5 0.1 2.1e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24586.1 - 3.2e-14 53.4 0.1 4.3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24586.1 - 5.3e-10 38.8 0.0 7.1e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM24586.1 - 7.8e-07 28.7 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM24586.1 - 0.00048 19.3 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 GAM24586.1 - 0.00074 18.8 0.0 0.0055 16.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 GAM24586.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 GAM24586.1 - 0.0073 15.9 0.1 0.0096 15.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain RhoGAP PF00620.22 GAM24587.1 - 1.2e-36 125.5 0.3 2.8e-36 124.4 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain CENP-F_leu_zip PF10473.4 GAM24587.1 - 0.019 14.8 2.0 0.033 14.0 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ank_2 PF12796.2 GAM24588.1 - 1.5e-05 25.2 0.0 0.0018 18.5 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24588.1 - 0.0066 16.5 0.0 0.66 10.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 GAM24588.1 - 0.025 14.4 0.0 1.5 8.7 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeat Ank_5 PF13857.1 GAM24588.1 - 0.043 14.0 0.0 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ocnus PF05005.10 GAM24590.1 - 1.3e-12 47.4 0.7 5.3e-12 45.5 0.1 2.1 2 1 0 2 2 2 1 Janus/Ocnus family (Ocnus) CENP-B_dimeris PF09026.5 GAM24590.1 - 0.021 15.0 1.0 0.034 14.3 0.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 GAM24590.1 - 0.037 13.8 1.5 0.052 13.3 1.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Ank_2 PF12796.2 GAM24591.1 - 8.6e-21 74.0 0.1 3.1e-20 72.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM24591.1 - 8.4e-18 63.2 1.2 2.5e-11 42.7 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 GAM24591.1 - 3.4e-14 52.5 2.3 1.1e-10 41.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM24591.1 - 4.8e-14 52.4 0.2 7.2e-08 32.7 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24591.1 - 6.9e-13 47.4 0.4 2.2e-06 27.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat RA PF00788.18 GAM24591.1 - 2.8e-07 30.9 0.0 4.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.1 GAM24591.1 - 0.013 15.3 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 PB1 PF00564.19 GAM24591.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Sigma70_r4 PF04545.11 GAM24592.1 - 0.042 13.1 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 PWWP PF00855.12 GAM24592.1 - 0.076 13.2 0.1 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 PWWP domain L51_S25_CI-B8 PF05047.11 GAM24594.1 - 8.8e-12 44.5 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain rRNA_methylase PF06962.7 GAM24594.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative rRNA methylase Pkinase PF00069.20 GAM24595.1 - 3e-44 151.1 0.5 5.6e-44 150.2 0.3 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24595.1 - 2e-11 43.4 0.0 5.9e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 GAM24595.1 - 0.00029 19.9 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAM24595.1 - 0.037 13.5 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 GAM24595.1 - 0.066 12.5 0.3 0.22 10.8 0.0 2.0 3 0 0 3 3 3 0 RIO1 family DUF788 PF05620.6 GAM24596.1 - 3.9e-42 143.9 0.5 4.5e-42 143.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Beta-lactamase2 PF13354.1 GAM24597.1 - 1.5e-18 67.0 0.0 6.9e-18 64.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase enzyme family LRR_4 PF12799.2 GAM24599.1 - 5.2e-18 64.2 40.8 0.00039 19.9 0.0 9.1 5 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM24599.1 - 1.3e-13 49.4 39.7 0.26 11.4 0.2 12.2 10 3 1 11 11 11 7 Leucine Rich repeat LRR_8 PF13855.1 GAM24599.1 - 3.3e-09 36.3 39.3 2e-05 24.2 0.9 6.5 4 1 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 GAM24599.1 - 0.41 10.8 42.0 6.2 7.2 0.3 11.2 9 4 3 12 12 12 0 Leucine Rich Repeat KRTAP PF11759.3 GAM24600.1 - 1.9 8.7 9.5 2.8 8.2 6.6 1.4 1 1 0 1 1 1 0 Keratin-associated matrix MACPF PF01823.14 GAM24601.1 - 0.042 13.5 5.4 0.081 12.6 2.6 2.2 1 1 1 2 2 2 0 MAC/Perforin domain RhoGEF PF00621.15 GAM24602.1 - 1.2e-52 178.4 3.6 2.9e-52 177.1 2.5 1.7 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAM24602.1 - 7.5e-18 64.2 12.9 1.4e-17 63.2 8.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAM24602.1 - 6.9e-14 51.9 2.8 7.3e-14 51.8 0.8 2.0 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 GAM24602.1 - 0.0096 15.7 0.5 0.035 14.0 0.3 1.9 1 0 0 1 1 1 1 PH domain Ribonuclease_3 PF00636.21 GAM24602.1 - 0.063 13.7 0.6 0.38 11.2 0.0 2.5 2 1 1 3 3 3 0 Ribonuclease III domain zf-DHHC PF01529.15 GAM24602.1 - 1.5 8.1 7.7 1.7 8.0 3.8 2.0 1 1 0 1 1 1 0 DHHC palmitoyltransferase Dynamin_N PF00350.18 GAM24603.1 - 1.4e-17 64.0 2.7 2.1e-17 63.4 0.1 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM24603.1 - 2e-06 27.7 0.0 1.2e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM24603.1 - 0.0097 15.4 0.0 0.028 13.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAM24603.1 - 0.014 14.5 0.0 0.22 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 GAM24603.1 - 0.021 15.1 14.6 0.057 13.7 0.5 4.0 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAM24603.1 - 0.042 14.1 0.0 0.042 14.1 0.0 3.3 4 0 0 4 4 4 0 ABC transporter Miro PF08477.8 GAM24603.1 - 0.05 14.1 0.1 0.24 11.8 0.0 2.3 2 0 0 2 2 1 0 Miro-like protein AAA_16 PF13191.1 GAM24603.1 - 0.066 13.1 0.2 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain LPP PF04728.8 GAM24603.1 - 0.077 12.8 0.2 0.26 11.1 0.1 1.9 1 0 0 1 1 1 0 Lipoprotein leucine-zipper AAA_33 PF13671.1 GAM24603.1 - 0.1 12.4 4.4 0.42 10.4 0.0 3.7 4 1 0 4 4 4 0 AAA domain MobB PF03205.9 GAM24603.1 - 0.13 12.0 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 7tm_2 PF00002.19 GAM24604.1 - 7.6e-24 84.1 12.3 9.5e-24 83.8 8.5 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 GAM24604.1 - 2.9e-21 75.6 8.3 4.6e-21 75.0 5.8 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.10 GAM24604.1 - 2.1e-10 39.8 5.5 4.3e-10 38.7 3.8 1.5 1 0 0 1 1 1 1 Ocular albinism type 1 protein Frizzled PF01534.12 GAM24604.1 - 1.5e-06 27.2 17.9 6.2e-05 21.9 3.2 2.8 1 1 2 3 3 3 2 Frizzled/Smoothened family membrane region DUF4199 PF13858.1 GAM24604.1 - 0.0022 17.9 3.8 0.0022 17.9 2.7 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4199) DUF2664 PF10867.3 GAM24605.1 - 0.034 14.7 0.6 0.13 12.9 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) DUF2217 PF10265.4 GAM24605.1 - 0.039 12.7 8.8 0.065 12.0 6.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 GAM24605.1 - 0.31 9.2 10.9 0.35 9.1 7.5 1.2 1 0 0 1 1 1 0 Transmembrane protein RRN3 PF05327.6 GAM24605.1 - 5.3 5.0 10.0 7.4 4.5 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 GAM24605.1 - 7.3 6.1 10.9 13 5.2 7.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region MCM PF00493.18 GAM24606.1 - 9.5e-102 340.1 0.0 1.4e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 GAM24606.1 - 1.2e-07 31.1 0.2 0.00036 19.7 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM24606.1 - 7.5e-07 28.9 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM24606.1 - 0.0051 17.0 0.4 0.026 14.7 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 GAM24606.1 - 0.017 14.5 0.1 0.31 10.5 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 GAM24606.1 - 0.044 13.2 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 GAM24606.1 - 0.11 12.6 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain VWC PF00093.13 GAM24607.1 - 2.4 8.3 6.8 7.5 6.7 0.2 2.5 2 0 0 2 2 2 0 von Willebrand factor type C domain zf-C3HC4_3 PF13920.1 GAM24608.1 - 1.4e-08 34.2 6.1 2.7e-08 33.3 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM24608.1 - 9e-08 32.0 6.1 2.7e-07 30.5 4.4 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM24608.1 - 3e-06 26.7 4.6 6.4e-05 22.5 3.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM24608.1 - 3.5e-06 26.7 8.1 8.2e-06 25.5 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM24608.1 - 6.2e-06 25.8 7.2 1.6e-05 24.5 5.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Med3 PF11593.3 GAM24608.1 - 0.00017 20.9 15.9 0.00017 20.9 11.0 2.1 2 0 0 2 2 1 1 Mediator complex subunit 3 fungal zf-C3HC4_4 PF15227.1 GAM24608.1 - 0.00023 20.9 7.1 0.0031 17.3 1.2 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM24608.1 - 0.0022 17.6 6.2 0.1 12.3 1.1 2.8 2 0 0 2 2 2 2 RING-type zinc-finger FHIPEP PF00771.15 GAM24608.1 - 0.011 14.1 0.0 0.011 14.1 0.0 1.7 2 0 0 2 2 2 0 FHIPEP family zf-RING_6 PF14835.1 GAM24608.1 - 0.019 14.7 4.3 0.04 13.7 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 GAM24608.1 - 0.091 12.3 7.0 0.26 10.9 4.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 GAM24608.1 - 0.2 11.5 3.5 0.69 9.7 2.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 GAM24608.1 - 0.64 10.1 12.9 0.23 11.6 4.8 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 GAM24608.1 - 0.65 9.5 6.4 2.2 7.9 4.4 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Pex14_N PF04695.8 GAM24608.1 - 4.5 7.3 15.9 4.4 7.3 2.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_2 PF12796.2 GAM24609.1 - 0.00016 21.9 0.4 0.2 12.0 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) RPAP3_C PF13877.1 GAM24609.1 - 0.19 11.6 3.2 0.51 10.3 0.1 3.1 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Ank_2 PF12796.2 GAM24610.1 - 6.9e-05 23.1 0.0 0.11 12.8 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM24611.1 - 3.2e-05 24.2 0.3 0.0046 17.2 0.0 3.9 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM24611.1 - 0.0025 18.2 0.0 0.34 11.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Cytochrome_cB PF11783.3 GAM24611.1 - 0.044 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c bacterial Ank_2 PF12796.2 GAM24612.1 - 0.0016 18.7 0.3 0.3 11.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24612.1 - 0.21 11.9 1.9 1.3e+02 3.3 0.1 4.9 5 0 0 5 5 5 0 Ankyrin repeat Cation_efflux PF01545.16 GAM24613.1 - 5.3e-60 202.9 7.1 5.3e-60 202.9 5.0 2.7 2 1 0 2 2 2 1 Cation efflux family Fe_hyd_lg_C PF02906.9 GAM24614.1 - 1.7e-88 296.5 0.0 2.5e-88 296.0 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HTH_Tnp_ISL3 PF13542.1 GAM24614.1 - 0.02 14.0 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 NDUF_B7 PF05676.8 GAM24616.1 - 3.7e-31 106.3 3.0 4.9e-31 105.9 2.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Mitoc_L55 PF09776.4 GAM24616.1 - 0.016 14.7 0.6 0.03 13.8 0.0 1.7 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L55 Cmc1 PF08583.5 GAM24616.1 - 0.05 13.3 2.7 0.081 12.7 1.9 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Band_7 PF01145.20 GAM24617.1 - 2.9e-25 89.2 0.6 4.1e-25 88.7 0.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 GAM24617.1 - 0.089 12.8 1.3 0.14 12.2 0.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 SH3_9 PF14604.1 GAM24618.1 - 6.5e-30 102.4 0.8 3.6e-14 52.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAM24618.1 - 4.4e-24 83.6 0.8 1.5e-14 53.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAM24618.1 - 2e-21 75.2 0.2 3.3e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 GAM24618.1 - 5.7e-09 36.0 3.9 6.2e-09 35.9 0.5 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PHA_synth_III_E PF09712.5 GAM24618.1 - 0.0021 17.5 2.0 0.82 9.0 0.2 2.2 2 0 0 2 2 2 2 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) TMF_TATA_bd PF12325.3 GAM24618.1 - 0.0067 16.1 5.8 0.015 15.0 4.0 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Rifin_STEVOR PF02009.11 GAM24620.1 - 0.35 10.4 7.8 0.7 9.4 5.4 1.5 1 0 0 1 1 1 0 Rifin/stevor family Rap_GAP PF02145.10 GAM24621.1 - 3.5e-60 202.6 0.2 1e-59 201.1 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP PH PF00169.24 GAM24621.1 - 9.9e-21 73.9 14.9 2.3e-13 50.2 0.4 4.6 5 0 0 5 5 5 3 PH domain PH_11 PF15413.1 GAM24621.1 - 8.4e-13 48.5 10.9 7e-05 23.0 0.9 5.0 2 1 1 3 3 3 3 Pleckstrin homology domain PH_6 PF15406.1 GAM24621.1 - 5.2e-06 26.4 0.0 1.8e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM24621.1 - 0.018 15.1 1.7 0.11 12.6 1.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2365 PF10157.4 GAM24622.1 - 0.0029 17.4 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) Helicase_C PF00271.26 GAM24623.1 - 3.5e-20 71.6 0.0 5.9e-19 67.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM24623.1 - 2.9e-19 69.1 0.4 2.1e-18 66.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.5 GAM24623.1 - 7.3e-19 67.4 0.2 7.1e-18 64.2 0.0 2.7 3 0 0 3 3 3 1 RQC domain HRDC PF00570.18 GAM24623.1 - 1.2e-11 44.1 0.0 2.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain EHN PF06441.7 GAM24623.1 - 0.071 13.0 0.3 0.31 10.9 0.2 2.1 1 0 0 1 1 1 0 Epoxide hydrolase N terminus AKNA PF12443.3 GAM24623.1 - 0.26 11.2 4.3 0.42 10.6 1.7 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor DUF1777 PF08648.7 GAM24623.1 - 0.62 9.7 8.0 0.1 12.3 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) zf-C3HC4_3 PF13920.1 GAM24624.1 - 1.4e-12 47.0 12.5 1.4e-12 47.0 8.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM24624.1 - 5.4e-06 26.3 13.7 5.4e-06 26.3 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM24624.1 - 0.0015 18.1 12.3 0.0015 18.1 8.5 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM24624.1 - 0.0022 17.6 13.6 0.0022 17.6 9.4 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM24624.1 - 0.057 13.2 15.0 0.071 12.9 9.1 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_4 PF15227.1 GAM24624.1 - 0.061 13.2 7.3 0.85 9.5 5.5 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF2039 PF10217.4 GAM24624.1 - 0.11 12.4 7.5 0.2 11.6 5.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) DUF1644 PF07800.7 GAM24624.1 - 4.3 7.1 9.6 4.2 7.2 0.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) Rhodanese PF00581.15 GAM24625.1 - 7e-12 45.6 0.0 1e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Baculo_11_kDa PF06143.6 GAM24625.1 - 0.046 13.0 0.1 0.081 12.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ras PF00071.17 GAM24626.1 - 3e-33 114.5 0.0 3.6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24626.1 - 6.4e-08 33.1 0.0 9.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24626.1 - 0.00019 20.6 0.1 0.00032 20.0 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM24626.1 - 0.024 14.0 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 GAM24627.1 - 2.2e-68 230.2 0.0 2.2e-68 230.2 0.0 4.1 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24627.1 - 5.2e-49 166.6 4.0 5.8e-49 166.5 0.0 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase adh_short PF00106.20 GAM24629.1 - 1.4e-34 119.4 0.3 1.7e-34 119.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM24629.1 - 1.1e-30 107.2 0.1 1.3e-30 106.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM24629.1 - 2e-14 53.6 0.2 2.9e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 GAM24629.1 - 0.00056 18.6 3.0 0.00095 17.9 2.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM24629.1 - 0.0011 18.5 0.9 0.0051 16.2 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM24629.1 - 0.0043 15.9 0.8 0.0072 15.2 0.5 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 GAM24629.1 - 0.014 15.1 1.0 0.056 13.2 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ATP_bind_2 PF03668.10 GAM24629.1 - 0.084 11.9 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family p450 PF00067.17 GAM24630.1 - 7.1e-69 232.5 0.1 9.6e-69 232.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 NOZZLE PF08744.5 GAM24631.1 - 0.12 11.6 0.3 0.14 11.5 0.2 1.0 1 0 0 1 1 1 0 Plant transcription factor NOZZLE Sec7 PF01369.15 GAM24632.1 - 7.2e-54 182.3 2.2 7.2e-54 182.3 1.5 2.9 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 GAM24632.1 - 4.2e-30 104.3 4.2 4.2e-30 104.3 2.9 4.2 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAM24632.1 - 7e-23 79.9 8.0 2e-18 65.6 0.0 5.3 5 0 0 5 5 5 3 Domain of unknown function (DUF1981) SRP14 PF02290.10 GAM24638.1 - 1.5e-25 88.8 0.1 1.5e-25 88.8 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Lumazine_bd PF12870.2 GAM24638.1 - 0.29 11.2 3.8 0.33 11.0 2.6 1.1 1 0 0 1 1 1 0 Lumazine-binding domain FHA PF00498.21 GAM24639.1 - 0.0011 19.0 0.1 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain UBA_4 PF14555.1 GAM24639.1 - 0.069 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain zf-CCHH PF10283.4 GAM24639.1 - 0.097 12.5 1.3 0.19 11.5 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif TAFII28 PF04719.9 GAM24640.1 - 5.6e-28 96.5 0.1 1.1e-27 95.6 0.1 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Porin_3 PF01459.17 GAM24642.1 - 4.4e-11 42.6 0.1 6e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic porin Fn3_assoc PF13287.1 GAM24643.1 - 3.7e-09 36.5 9.1 0.17 12.0 0.5 5.5 4 0 0 4 4 4 4 Fn3 associated CHB_HEX_C PF03174.8 GAM24643.1 - 2.7e-08 33.5 12.7 0.14 12.0 1.3 5.6 5 0 0 5 5 5 3 Chitobiase/beta-hexosaminidase C-terminal domain Laminin_G_3 PF13385.1 GAM24643.1 - 3.4e-07 30.6 0.0 3.4e-07 30.6 0.0 3.6 4 1 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily CHB_HEX_C_1 PF13290.1 GAM24643.1 - 4.1e-05 23.2 14.9 0.3 10.9 0.1 5.6 6 0 0 6 6 6 3 Chitobiase/beta-hexosaminidase C-terminal domain DUF2501 PF10696.4 GAM24643.1 - 0.07 13.1 0.1 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) zf-CCHC_3 PF13917.1 GAM24644.1 - 0.35 10.6 18.5 0.93 9.2 0.3 3.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 GAM24644.1 - 1.7 8.3 16.1 0.21 11.2 0.8 3.0 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC PF00098.18 GAM24644.1 - 1.7 8.6 23.1 0.12 12.3 2.1 3.6 3 1 0 3 3 3 0 Zinc knuckle ELMO_CED12 PF04727.8 GAM24645.1 - 4e-34 117.6 0.1 7.6e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family RdRP PF05183.7 GAM24646.1 - 3.5e-107 359.4 0.1 2e-67 228.2 0.0 2.3 2 0 0 2 2 2 2 RNA dependent RNA polymerase Helicase_C PF00271.26 GAM24646.1 - 1.8e-16 59.7 0.2 5e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM24646.1 - 6.3e-16 58.7 0.0 1.7e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM24646.1 - 1.9e-13 50.2 0.2 5.6e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 GAM24646.1 - 0.00059 18.7 0.5 0.0011 17.7 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 GAM24646.1 - 0.0074 15.6 0.0 0.019 14.2 0.0 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_19 PF13245.1 GAM24646.1 - 0.39 10.5 0.0 19 5.0 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain FNIP PF05725.7 GAM24647.1 - 5.9e-58 192.5 14.5 4.6e-12 45.6 0.0 9.2 6 3 1 9 9 9 6 FNIP Repeat LRR_8 PF13855.1 GAM24647.1 - 0.22 11.3 5.3 3.6 7.4 0.2 4.3 5 1 1 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 GAM24647.1 - 0.5 10.7 13.0 75 4.2 0.0 8.1 10 0 0 10 10 10 0 Leucine rich repeat Neur_chan_memb PF02932.11 GAM24648.1 - 2.2 8.1 6.7 4 7.2 4.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dimer_Tnp_hAT PF05699.9 GAM24649.1 - 2.1e-12 46.4 0.0 4.5e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 GAM24649.1 - 0.00019 21.3 3.0 0.00031 20.6 1.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4413) Ephrin_lbd PF01404.14 GAM24649.1 - 0.046 13.4 0.4 0.081 12.7 0.3 1.4 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain RVT_1 PF00078.22 GAM24650.1 - 6.9e-21 74.5 0.4 1.3e-20 73.7 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 GAM24650.1 - 2.1e-06 27.4 0.2 4.3e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 GAM24650.1 - 1.1e-05 25.8 0.0 2.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 GAM24650.1 - 0.066 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 GAM24650.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Nup35_RRM_2 PF14605.1 GAM24651.1 - 0.056 13.2 0.2 6.4 6.6 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Pox_F17 PF04767.7 GAM24651.1 - 6 7.1 9.4 0.69 10.2 2.8 1.9 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein Formyl_trans_N PF00551.14 GAM24652.1 - 0.061 12.8 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Formyl transferase PRP21_like_P PF12230.3 GAM24652.1 - 0.063 12.7 0.4 0.074 12.5 0.3 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein AAA_14 PF13173.1 GAM24656.1 - 0.082 12.8 0.1 0.74 9.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain DisA_N PF02457.11 GAM24657.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Pox_Ag35 PF03286.9 GAM24658.1 - 0.047 13.2 5.5 0.094 12.2 3.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rifin_STEVOR PF02009.11 GAM24658.1 - 0.075 12.6 5.1 1.8 8.1 0.0 2.3 2 1 0 2 2 2 0 Rifin/stevor family YfhD PF14151.1 GAM24658.1 - 0.11 12.5 2.4 0.29 11.2 1.6 1.6 1 0 0 1 1 1 0 YfhD-like protein TT_ORF2 PF02957.10 GAM24658.1 - 0.7 10.6 4.0 1.2 9.8 2.8 1.4 1 0 0 1 1 1 0 TT viral ORF2 UCH PF00443.24 GAM24659.1 - 1.2e-66 224.5 1.5 1.9e-66 223.9 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM24659.1 - 1.8e-28 99.8 4.4 1.3e-24 87.2 0.5 2.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 GAM24659.1 - 1.2e-08 34.9 16.9 1.2e-08 34.9 11.7 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 GAM24660.1 - 3.8e-14 52.2 3.9 1.3e-13 50.5 2.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM24660.1 - 1.1e-09 37.8 4.2 2.6e-09 36.6 2.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM24660.1 - 2e-09 37.3 4.3 3.8e-09 36.4 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM24660.1 - 4e-09 35.9 2.1 7.4e-09 35.1 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM24660.1 - 1.5e-07 30.9 5.3 3.1e-07 29.9 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM24660.1 - 5.7e-07 29.5 2.6 5.7e-07 29.5 1.8 3.0 3 1 0 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 GAM24660.1 - 0.011 15.4 3.8 0.038 13.6 2.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 GAM24660.1 - 0.011 15.2 6.1 0.021 14.4 4.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 GAM24660.1 - 1.6 8.6 5.4 4.5 7.2 3.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 GAM24661.1 - 7.2e-59 199.0 0.0 1.7e-58 197.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24661.1 - 3.2e-44 150.9 0.0 1.5e-43 148.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24661.1 - 0.00014 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM24661.1 - 0.0014 18.4 0.0 0.0041 16.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family PHD PF00628.24 GAM24662.1 - 4e-15 55.2 26.3 2.9e-08 33.2 3.5 3.5 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.1 GAM24662.1 - 1.3e-06 28.4 23.8 0.05 13.7 1.8 3.6 2 1 1 3 3 3 3 PHD-like zinc-binding domain PHD_2 PF13831.1 GAM24662.1 - 0.0032 16.7 0.3 0.0032 16.7 0.2 4.3 4 0 0 4 4 4 2 PHD-finger UQ_con PF00179.21 GAM24663.1 - 1.1e-44 151.2 0.0 1.8e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 GAM24663.1 - 0.084 12.0 7.7 0.12 11.5 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RWD PF05773.17 GAM24663.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.3 3 1 0 3 3 3 0 RWD domain SDA1 PF05285.7 GAM24663.1 - 0.67 9.1 11.2 1.1 8.5 7.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 GAM24663.1 - 1.9 6.3 12.0 2.6 5.8 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L29 PF00831.18 GAM24664.1 - 1.8e-14 53.1 2.1 1.8e-14 53.1 1.5 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein mIF3 PF14877.1 GAM24664.1 - 0.035 13.4 1.3 0.056 12.8 0.3 1.8 1 1 0 1 1 1 0 Mitochondrial translation initiation factor DUF2228 PF10228.4 GAM24664.1 - 0.074 12.5 4.0 0.093 12.2 2.7 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Ins_P5_2-kin PF06090.7 GAM24665.1 - 1.3e-66 224.7 0.2 1.5e-66 224.5 0.1 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Sen15 PF09631.5 GAM24665.1 - 0.11 12.6 0.1 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Sen15 protein RicinB_lectin_2 PF14200.1 GAM24666.1 - 2.4e-13 50.3 3.5 0.00089 19.5 0.4 4.5 1 1 4 5 5 5 5 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 GAM24666.1 - 2.5e-07 30.7 3.0 0.011 15.7 2.4 3.5 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Kinesin PF00225.18 GAM24669.1 - 7.7e-108 360.1 2.1 7.7e-108 360.1 1.5 2.5 3 0 0 3 3 3 1 Kinesin motor domain TBP-binding PF09247.6 GAM24669.1 - 0.11 12.7 2.9 0.32 11.2 0.2 3.1 2 1 1 3 3 3 0 TATA box-binding protein binding AAA_22 PF13401.1 GAM24669.1 - 0.18 11.9 0.1 0.18 11.9 0.1 3.3 3 2 0 3 3 3 0 AAA domain GPP34 PF05719.6 GAM24670.1 - 3.1e-14 53.5 0.0 3.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) zf-UBR PF02207.15 GAM24671.1 - 7e-17 60.9 11.7 7e-17 60.9 8.1 3.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 GAM24671.1 - 0.00026 20.7 0.7 0.00026 20.7 0.5 3.9 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.1 GAM24671.1 - 0.99 9.0 12.4 1.8 8.1 0.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Ras PF00071.17 GAM24672.1 - 2e-49 167.0 0.4 2.3e-49 166.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM24672.1 - 4.3e-19 68.4 0.0 5.1e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM24672.1 - 6.4e-16 58.9 0.3 1.4e-15 57.7 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 GAM24672.1 - 3.7e-10 39.3 0.2 4.8e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM24672.1 - 8.6e-06 25.3 0.0 0.0003 20.2 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM24672.1 - 4.7e-05 23.3 0.0 8.7e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 GAM24672.1 - 0.0033 17.5 0.0 0.028 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 GAM24672.1 - 0.005 16.0 0.1 0.012 14.8 0.0 1.7 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 GAM24672.1 - 0.015 15.1 0.0 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 Dynamin family AAA_14 PF13173.1 GAM24672.1 - 0.045 13.6 0.1 0.21 11.4 0.0 1.9 1 1 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.18 GAM24673.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.18 GAM24674.1 - 0.008 16.1 0.1 0.0088 16.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GTP_EFTU PF00009.22 GAM24675.1 - 1.1e-42 145.6 0.0 1.6e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM24675.1 - 3.7e-24 84.7 0.1 3.5e-23 81.6 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 GAM24675.1 - 1.2e-05 25.1 0.0 2.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM24675.1 - 0.00059 19.6 0.1 0.36 10.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 GAM24675.1 - 0.0034 17.8 0.0 0.0093 16.4 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 GAM24675.1 - 0.0042 17.1 0.0 0.0091 16.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 GAM24675.1 - 0.013 14.9 0.0 1.9 7.9 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ceramidase_alk PF04734.8 GAM24678.1 - 8.7e-278 922.7 0.3 9.8e-278 922.5 0.2 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Kinesin PF00225.18 GAM24679.1 - 8.2e-110 366.6 0.0 2e-109 365.3 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Fib_alpha PF08702.5 GAM24679.1 - 0.018 15.1 9.5 0.96 9.5 2.2 3.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family COMP PF11598.3 GAM24679.1 - 0.6 10.2 2.5 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DUF342 PF03961.8 GAM24679.1 - 6.6 5.0 15.9 1.6 7.0 5.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Peptidase_M8 PF01457.11 GAM24680.1 - 2.8e-65 220.6 0.9 3.7e-65 220.2 0.7 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF3644 PF12358.3 GAM24682.1 - 0.083 13.1 1.2 0.77 10.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Peptidase_M15_3 PF08291.6 GAM24683.1 - 0.047 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M15 AAA_16 PF13191.1 GAM24684.1 - 0.029 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rhomboid PF01694.17 GAM24687.1 - 0.0081 16.1 1.2 0.011 15.7 0.8 1.2 1 0 0 1 1 1 1 Rhomboid family Glt_symporter PF03616.9 GAM24688.1 - 0.072 11.5 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Herpes_capsid PF06112.6 GAM24688.1 - 0.64 10.0 5.6 0.71 9.9 3.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Period_C PF12114.3 GAM24688.1 - 2.1 7.9 5.6 2.7 7.5 3.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Serglycin PF04360.7 GAM24689.1 - 0.39 10.4 7.1 0.2 11.3 3.2 1.8 2 0 0 2 2 2 0 Serglycin Secretin_N_2 PF07655.8 GAM24689.1 - 1.7 9.1 9.7 2.9 8.3 6.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Kelch_4 PF13418.1 GAM24690.1 - 2.3e-14 52.8 2.9 0.00031 20.4 0.0 4.9 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24690.1 - 3.4e-13 49.1 6.6 0.00052 20.0 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM24690.1 - 2e-09 37.3 2.5 0.084 13.0 0.0 4.8 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24690.1 - 1.3e-06 27.8 6.2 0.077 12.5 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 GAM24690.1 - 6.2e-05 22.8 2.5 0.24 11.4 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM24690.1 - 0.00091 18.9 5.3 1.6 8.6 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Endonuc-MspI PF09208.5 GAM24690.1 - 0.22 10.5 4.0 0.87 8.6 1.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease MspI Kelch_6 PF13964.1 GAM24691.1 - 1.9e-10 40.4 0.9 0.0028 17.7 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM24691.1 - 3.9e-08 32.9 5.3 0.0016 18.2 0.0 4.4 3 1 1 4 4 4 2 Galactose oxidase, central domain Baculo_PEP_C PF04513.7 GAM24691.1 - 2.3e-06 27.4 2.2 3.6e-06 26.8 1.5 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_3 PF13415.1 GAM24691.1 - 4.3e-06 26.7 0.5 1.1 9.5 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM24691.1 - 5.6e-05 22.7 0.9 0.27 11.0 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 GAM24691.1 - 0.00018 20.9 0.7 1.7 8.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif DUF1664 PF07889.7 GAM24691.1 - 0.069 12.9 1.1 0.13 12.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kelch_5 PF13854.1 GAM24691.1 - 0.16 11.9 4.9 3 7.8 0.2 3.2 2 1 1 3 3 3 0 Kelch motif Kelch_6 PF13964.1 GAM24692.1 - 7.8e-11 41.6 8.0 0.0003 20.8 0.1 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM24692.1 - 2.1e-10 40.1 3.3 0.00019 21.1 0.1 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24692.1 - 4.7e-08 32.9 2.0 0.4 10.9 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24692.1 - 3.4e-07 30.0 3.7 0.023 14.6 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 GAM24692.1 - 8.5e-05 22.0 10.0 0.0099 15.4 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 GAM24692.1 - 0.00047 19.8 6.7 0.096 12.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Baculo_PEP_C PF04513.7 GAM24692.1 - 0.0013 18.5 3.0 0.0027 17.5 2.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF603 PF04645.7 GAM24692.1 - 0.34 10.8 4.3 0.75 9.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF603 Kelch_6 PF13964.1 GAM24693.1 - 2.9e-14 52.5 3.7 9.1e-05 22.4 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM24693.1 - 7.1e-14 51.3 2.4 6.2e-05 22.6 0.1 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24693.1 - 9.7e-11 41.5 2.3 0.019 15.1 0.0 4.6 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24693.1 - 8.1e-09 34.8 1.8 0.00052 19.5 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM24693.1 - 2.1e-05 24.0 0.7 0.23 11.2 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Baculo_PEP_C PF04513.7 GAM24693.1 - 3.6e-05 23.5 3.6 0.0001 22.1 2.5 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_5 PF13854.1 GAM24693.1 - 0.00061 19.6 2.2 0.38 10.7 0.1 2.9 3 0 0 3 3 3 2 Kelch motif zf-B_box PF00643.19 GAM24693.1 - 0.015 15.2 6.2 0.027 14.3 4.3 1.5 1 0 0 1 1 1 0 B-box zinc finger DUF1664 PF07889.7 GAM24693.1 - 0.64 9.8 5.0 8.1 6.2 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-B_box PF00643.19 GAM24694.1 - 9.1e-12 44.6 24.7 4.1e-06 26.5 6.2 2.4 2 0 0 2 2 2 2 B-box zinc finger Kelch_6 PF13964.1 GAM24694.1 - 9.3e-12 44.5 3.4 0.0005 20.1 0.0 4.6 3 1 1 4 4 3 2 Kelch motif Kelch_4 PF13418.1 GAM24694.1 - 2.8e-10 39.8 10.8 2.3e-05 24.0 0.0 4.9 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24694.1 - 8.4e-10 38.5 2.2 0.036 14.2 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Baculo_PEP_C PF04513.7 GAM24694.1 - 2.1e-09 37.3 15.3 7.9e-06 25.7 3.3 2.7 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_1 PF01344.20 GAM24694.1 - 1.1e-05 24.8 11.8 0.11 12.0 0.0 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 GAM24694.1 - 1.4e-05 24.6 1.6 0.36 10.6 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM24694.1 - 4.3e-05 23.3 7.6 0.07 13.1 0.1 4.6 5 0 0 5 5 5 1 Kelch motif Apolipoprotein PF01442.13 GAM24694.1 - 0.00013 21.5 0.9 0.052 13.0 0.1 2.5 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain IBR PF01485.16 GAM24694.1 - 0.0015 18.3 8.4 0.076 12.8 1.2 2.5 2 0 0 2 2 2 2 IBR domain Phage_Orf51 PF06194.6 GAM24694.1 - 0.019 15.0 0.4 8.5 6.5 0.0 3.0 2 1 1 3 3 3 0 Phage Conserved Open Reading Frame 51 OmpH PF03938.9 GAM24694.1 - 0.051 13.5 1.2 2.1 8.2 0.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4065 PF13274.1 GAM24694.1 - 0.076 13.7 7.4 2.9 8.6 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DUF2630 PF10944.3 GAM24694.1 - 0.2 11.7 8.1 1.7 8.7 0.1 3.9 4 0 0 4 4 3 0 Protein of unknown function (DUF2630) zf-UBR PF02207.15 GAM24694.1 - 0.3 10.8 21.2 0.14 11.8 2.6 2.9 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF1664 PF07889.7 GAM24694.1 - 0.51 10.1 21.9 0.87 9.3 2.3 4.9 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) FYVE_2 PF02318.11 GAM24694.1 - 0.54 10.1 14.3 0.59 10.0 0.7 3.1 3 0 0 3 3 2 0 FYVE-type zinc finger DUF745 PF05335.8 GAM24694.1 - 1.3 8.4 5.1 11 5.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Occludin_ELL PF07303.8 GAM24694.1 - 1.5 9.6 8.6 0.55 10.9 1.4 2.9 2 1 1 3 3 3 0 Occludin homology domain NPV_P10 PF05531.7 GAM24694.1 - 2.3 8.5 17.4 26 5.1 0.0 4.7 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein RPW8 PF05659.6 GAM24694.1 - 2.7 7.5 7.2 4.4 6.8 0.0 3.9 3 2 2 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Cytochrom_B562 PF07361.6 GAM24694.1 - 3 8.2 10.9 1.1 9.7 0.2 3.8 3 2 1 4 4 4 0 Cytochrome b562 Lar_restr_allev PF14354.1 GAM24694.1 - 3.7 7.9 6.8 2.8 8.2 0.8 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF4371 PF14291.1 GAM24694.1 - 3.8 6.9 17.4 0.15 11.6 1.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4371) Spectrin PF00435.16 GAM24694.1 - 6.4 7.1 12.7 17 5.7 0.9 2.8 2 0 0 2 2 2 0 Spectrin repeat Kelch_4 PF13418.1 GAM24695.1 - 6.2e-12 45.0 2.9 0.00036 20.2 0.0 4.6 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24695.1 - 1.2e-10 41.1 2.7 0.0018 18.3 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM24695.1 - 1.9e-07 31.0 0.6 0.27 11.4 0.1 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-B_box PF00643.19 GAM24695.1 - 6.5e-07 29.1 9.4 1.1e-06 28.3 6.5 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.20 GAM24695.1 - 9.7e-06 25.0 5.1 0.64 9.6 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 GAM24695.1 - 2.7e-05 23.9 2.0 0.044 13.7 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Baculo_PEP_C PF04513.7 GAM24695.1 - 3.2e-05 23.7 0.7 6.1e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_2 PF07646.10 GAM24695.1 - 0.022 14.5 4.2 4.4 7.2 0.0 3.8 4 0 0 4 4 4 0 Kelch motif IBR PF01485.16 GAM24695.1 - 0.31 10.9 5.0 0.8 9.6 3.4 1.7 1 0 0 1 1 1 0 IBR domain DUF1664 PF07889.7 GAM24695.1 - 0.39 10.5 3.6 0.72 9.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Vhr1 PF04001.8 GAM24695.1 - 0.67 9.9 4.0 2.7 7.9 1.3 2.6 2 0 0 2 2 2 0 Transcription factor Vhr1 GATA PF00320.22 GAM24697.1 - 7.5e-16 57.1 6.8 1.5e-15 56.2 4.7 1.6 1 0 0 1 1 1 1 GATA zinc finger BioY PF02632.9 GAM24698.1 - 6.3e-42 142.7 13.5 1.1e-41 141.9 9.4 1.4 1 0 0 1 1 1 1 BioY family ubiquitin PF00240.18 GAM24698.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Neur_chan_memb PF02932.11 GAM24698.1 - 0.13 12.1 1.6 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3792 PF12670.2 GAM24698.1 - 9.7 6.0 18.7 0.58 10.0 7.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) Kelch_6 PF13964.1 GAM24699.1 - 4.6e-17 61.3 3.4 0.00018 21.5 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM24699.1 - 4.9e-13 48.6 4.8 0.00012 21.7 0.0 5.5 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24699.1 - 1.1e-08 35.0 1.0 0.17 12.1 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24699.1 - 3.1e-05 23.8 1.0 0.14 12.1 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 GAM24699.1 - 4.9e-05 22.7 1.6 0.32 10.5 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Baculo_PEP_C PF04513.7 GAM24699.1 - 0.0014 18.4 1.0 0.0027 17.5 0.7 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_2 PF07646.10 GAM24699.1 - 0.0068 16.1 0.9 2 8.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 GAM24700.1 - 1e-07 31.6 5.4 2e-07 30.6 0.1 3.2 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24700.1 - 1.6e-07 31.1 4.5 9.7e-05 22.3 0.1 4.0 3 1 1 4 4 4 2 Kelch motif zf-B_box PF00643.19 GAM24700.1 - 4.1e-05 23.3 10.5 9.1e-05 22.2 7.3 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_3 PF13415.1 GAM24700.1 - 0.00012 22.1 1.8 0.33 11.1 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24700.1 - 0.0003 20.2 7.0 0.00049 19.5 0.1 3.9 4 0 0 4 4 4 1 Kelch motif Baculo_PEP_C PF04513.7 GAM24700.1 - 0.00047 20.0 0.3 0.00084 19.1 0.2 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 GAM24700.1 - 0.0019 18.0 4.2 0.041 13.6 0.8 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Kelch_2 PF07646.10 GAM24700.1 - 0.0025 17.5 0.1 0.0025 17.5 0.0 2.3 3 0 0 3 3 3 1 Kelch motif IBR PF01485.16 GAM24700.1 - 0.31 10.9 5.3 0.69 9.8 3.7 1.5 1 0 0 1 1 1 0 IBR domain DUF1690 PF07956.6 GAM24700.1 - 8.1 6.4 9.8 27 4.7 0.2 2.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Kelch_6 PF13964.1 GAM24701.1 - 3.8e-09 36.3 1.7 5.2e-05 23.2 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM24701.1 - 1e-08 34.8 1.5 1.1e-05 25.0 0.1 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24701.1 - 2.5e-07 30.1 1.4 0.0041 16.6 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM24701.1 - 0.00017 21.6 1.0 0.094 12.9 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM24701.1 - 0.00029 20.4 0.3 0.27 11.0 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM24701.1 - 0.013 15.3 0.1 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Kelch motif PA14 PF07691.7 GAM24702.1 - 1.4e-16 60.4 0.2 2.5e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 GAM24702.1 - 1.9e-06 27.5 24.7 0.0001 22.0 6.0 15.2 16 2 1 17 17 17 7 Dictyostelium (slime mold) repeat Borealin PF10512.4 GAM24705.1 - 0.028 14.3 0.2 0.092 12.6 0.2 1.7 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 Transaldolase PF00923.14 GAM24707.1 - 6e-92 307.8 0.1 6.8e-92 307.6 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Med21 PF11221.3 GAM24707.1 - 0.0076 16.2 0.1 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Subunit 21 of Mediator complex FNIP PF05725.7 GAM24708.1 - 1.8e-36 123.7 20.5 4.3e-12 45.7 0.0 5.5 3 1 3 6 6 6 6 FNIP Repeat HCaRG PF07258.9 GAM24709.1 - 2.7e-45 154.1 0.7 2.9e-45 153.9 0.5 1.0 1 0 0 1 1 1 1 HCaRG protein HHH_4 PF14490.1 GAM24709.1 - 0.014 15.0 0.1 6 6.7 0.0 2.5 2 1 1 3 3 3 0 Helix-hairpin-helix containing domain Pho88 PF10032.4 GAM24709.1 - 0.041 13.0 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphate transport (Pho88) M11L PF11099.3 GAM24709.1 - 0.048 13.4 1.3 0.097 12.4 0.1 1.9 1 1 1 2 2 2 0 Apoptosis regulator M11L like PI3_PI4_kinase PF00454.22 GAM24709.1 - 0.055 12.9 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase WD40 PF00400.27 GAM24710.1 - 9.6e-61 199.6 25.0 1.2e-10 40.8 0.4 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat CLTH PF10607.4 GAM24710.1 - 9.7e-05 22.0 0.3 0.00019 21.1 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Nucleoporin_N PF08801.6 GAM24710.1 - 0.0024 16.7 7.3 0.15 10.7 0.1 3.3 2 1 1 3 3 3 2 Nup133 N terminal like Glyco_trans_4_2 PF13477.1 GAM24710.1 - 0.0029 17.4 0.7 2.2 8.1 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase 4-like Coatomer_WDAD PF04053.9 GAM24710.1 - 0.0046 15.8 6.1 0.069 11.9 0.0 3.6 3 1 1 4 4 4 2 Coatomer WD associated region Nup160 PF11715.3 GAM24710.1 - 0.35 8.9 8.4 2.5 6.1 0.2 3.5 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Kelch_4 PF13418.1 GAM24711.1 - 2.2e-11 43.3 3.4 6.5e-07 29.0 0.0 5.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24711.1 - 2.7e-10 39.6 4.9 0.0012 18.3 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 GAM24711.1 - 5.2e-09 35.9 8.7 0.058 13.5 0.0 5.4 4 2 2 6 6 6 3 Kelch motif zf-B_box PF00643.19 GAM24711.1 - 7.3e-09 35.3 6.8 1.5e-08 34.3 4.7 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_2 PF07646.10 GAM24711.1 - 1e-06 28.2 1.1 0.3 10.9 0.0 3.7 2 1 1 3 3 3 3 Kelch motif Kelch_5 PF13854.1 GAM24711.1 - 6.7e-06 25.9 3.2 0.017 15.0 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM24711.1 - 4.4e-05 23.5 7.5 0.14 12.3 0.0 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain IBR PF01485.16 GAM24711.1 - 0.022 14.6 2.2 0.062 13.1 1.5 1.7 1 0 0 1 1 1 0 IBR domain AAA_5 PF07728.9 GAM24711.1 - 0.077 12.7 0.1 0.23 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DDE_Tnp_4 PF13359.1 GAM24712.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM24712.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain SOG2 PF10428.4 GAM24713.1 - 0.042 12.4 2.6 0.042 12.5 1.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dicty_REP PF05086.7 GAM24713.1 - 4 5.0 6.4 6.3 4.4 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.11 GAM24715.1 - 6.5e-27 94.1 41.3 6.5e-27 94.1 28.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM24715.1 - 5.8e-07 28.4 5.0 5.8e-07 28.4 3.5 2.8 1 1 1 3 3 3 2 Sugar (and other) transporter DBR1 PF05011.8 GAM24716.1 - 1.1e-19 70.8 4.5 1.2e-16 60.9 0.0 2.6 2 1 1 3 3 3 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 GAM24716.1 - 1.1e-08 34.7 0.9 2.3e-08 33.6 0.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 GAM24716.1 - 4.3e-05 23.4 0.0 8.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2639 PF11121.3 GAM24716.1 - 0.018 14.5 0.1 0.059 12.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) Uds1 PF15456.1 GAM24716.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Up-regulated During Septation Kelch_4 PF13418.1 GAM24717.1 - 2.7e-15 55.8 4.7 5.1e-08 32.5 0.2 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24717.1 - 4.2e-11 42.5 12.0 0.00039 20.4 0.1 5.2 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 GAM24717.1 - 1.1e-09 37.6 10.8 2.4e-05 23.7 0.1 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM24717.1 - 1.8e-09 37.5 5.1 0.0082 16.2 0.1 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM24717.1 - 1.9e-08 33.7 4.8 0.0037 16.9 0.1 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 GAM24717.1 - 0.0011 18.8 3.9 0.18 11.8 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 GAM24718.1 - 1.6e-12 46.9 7.5 2.8e-06 26.9 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24718.1 - 8.3e-12 44.7 5.0 0.0037 17.3 0.0 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.1 GAM24718.1 - 5.3e-07 29.6 4.0 0.91 9.7 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24718.1 - 1.1e-06 28.0 4.9 0.015 14.8 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM24718.1 - 2.6e-06 26.9 1.2 0.42 10.4 0.0 4.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 GAM24718.1 - 0.0046 16.8 3.9 0.7 9.9 0.1 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 GAM24719.1 - 2.1e-12 46.6 6.1 7.4e-05 22.4 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM24719.1 - 2.3e-12 46.4 6.4 0.00012 22.0 0.0 4.2 3 1 1 4 4 4 3 Kelch motif Kelch_3 PF13415.1 GAM24719.1 - 6.4e-09 35.7 5.8 0.022 14.9 0.0 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24719.1 - 3.7e-07 29.9 4.7 0.022 14.6 0.1 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 GAM24719.1 - 6.7e-07 28.8 0.9 0.83 9.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 GAM24719.1 - 5.5e-05 22.6 7.6 0.093 12.2 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 GAM24720.1 - 2.3e-11 43.3 5.3 0.002 18.2 0.2 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM24720.1 - 2.4e-10 39.9 9.7 9.2e-05 22.1 0.1 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM24720.1 - 1.1e-07 31.7 5.1 0.46 10.7 0.2 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM24720.1 - 6e-07 29.2 2.7 0.036 14.0 0.1 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.10 GAM24720.1 - 7.5e-07 28.6 1.6 0.19 11.5 0.1 4.0 3 0 0 3 3 3 3 Kelch motif zf-B_box PF00643.19 GAM24720.1 - 2.1e-06 27.4 12.2 4.2e-06 26.5 8.5 1.4 1 0 0 1 1 1 1 B-box zinc finger Kelch_1 PF01344.20 GAM24720.1 - 5.7e-06 25.7 8.9 0.3 10.6 0.0 5.0 6 0 0 6 6 6 3 Kelch motif DUF2200 PF09966.4 GAM24720.1 - 0.055 13.3 0.4 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Baculo_PEP_C PF04513.7 GAM24721.1 - 0.029 14.1 1.4 0.032 14.0 1.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3067 PF11267.3 GAM24721.1 - 0.062 13.3 0.2 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3067) Kelch_6 PF13964.1 GAM24722.1 - 1e-10 41.3 4.1 0.021 14.9 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM24722.1 - 2.9e-09 36.8 0.5 0.0076 16.3 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM24722.1 - 2.8e-08 33.4 3.5 4.5e-06 26.3 0.0 4.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24722.1 - 3.9e-08 32.7 7.6 0.00016 21.1 0.2 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM24722.1 - 8.4e-07 28.5 2.0 0.77 9.6 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 GAM24722.1 - 0.0029 17.5 2.3 0.12 12.3 0.0 3.2 3 0 0 3 3 3 1 Kelch motif tRNA_m1G_MT PF01746.16 GAM24722.1 - 0.039 13.5 0.1 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase MAP65_ASE1 PF03999.7 GAM24723.1 - 1.2e-47 162.8 45.4 1.1e-43 149.7 19.8 2.2 1 1 2 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) Matrilin_ccoil PF10393.4 GAM24723.1 - 0.048 13.0 4.4 3.2 7.1 0.2 3.6 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Dpoe2NT PF12213.3 GAM24723.1 - 0.63 9.9 6.5 0.16 11.9 0.3 3.3 4 0 0 4 4 4 0 DNA polymerases epsilon N terminal UPF0240 PF06784.6 GAM24725.1 - 2.7e-06 27.1 1.3 1.6e-05 24.7 0.7 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) MRP-L20 PF12824.2 GAM24725.1 - 0.0015 18.5 2.6 0.0018 18.2 0.5 2.1 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 CUE PF02845.11 GAM24726.1 - 0.0031 16.9 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 CUE domain UBA PF00627.26 GAM24726.1 - 0.0096 15.7 0.1 0.16 11.8 0.0 2.9 2 1 1 3 3 3 1 UBA/TS-N domain Baculo_PEP_C PF04513.7 GAM24726.1 - 0.014 15.1 3.0 0.014 15.1 2.1 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2422 PF10337.4 GAM24726.1 - 0.022 13.5 1.4 0.038 12.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) UBA_4 PF14555.1 GAM24726.1 - 0.03 13.8 0.1 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain UPF0118 PF01594.11 GAM24726.1 - 0.35 9.8 0.6 0.61 9.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 4HBT PF03061.17 GAM24727.1 - 0.00023 21.2 0.2 0.00094 19.2 0.0 1.8 1 1 1 2 2 2 1 Thioesterase superfamily DUF2807 PF10988.3 GAM24727.1 - 0.014 14.9 1.5 0.028 13.9 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2807) MCM PF00493.18 GAM24728.1 - 1.5e-125 418.3 0.0 2.3e-125 417.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 GAM24728.1 - 9.4e-11 41.2 0.1 9.6e-07 28.1 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM24728.1 - 2.4e-08 33.7 0.0 8.5e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.1 GAM24728.1 - 6.6e-06 26.6 0.7 2.6e-05 24.6 0.0 2.3 2 1 1 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.6 GAM24728.1 - 4.9e-05 22.9 0.0 0.00037 20.0 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM24728.1 - 0.00076 19.5 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Lon_2 PF13337.1 GAM24728.1 - 0.0022 16.4 0.0 0.0053 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease FtsK_SpoIIIE PF01580.13 GAM24728.1 - 0.016 14.7 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 GAM24728.1 - 0.051 13.2 2.3 2.1 8.0 0.2 3.2 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.1 GAM24728.1 - 0.055 12.9 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM24728.1 - 0.069 13.2 0.0 0.59 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 GAM24728.1 - 0.077 13.2 0.1 0.57 10.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2624 PF11116.3 GAM24728.1 - 0.079 13.4 0.1 4.6 7.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) RNA_helicase PF00910.17 GAM24728.1 - 0.084 13.0 1.3 45 4.2 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ADH_zinc_N PF00107.21 GAM24729.1 - 7.8e-17 61.0 0.1 1.9e-16 59.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM24729.1 - 2.4e-12 46.5 0.0 4.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM24729.1 - 4.7e-05 24.2 0.2 0.00016 22.5 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase MS_channel PF00924.13 GAM24729.1 - 0.038 13.3 1.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel Pkinase_Tyr PF07714.12 GAM24730.1 - 1.3e-95 319.3 0.0 1.9e-57 194.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 GAM24730.1 - 9.2e-88 293.7 7.3 2.7e-54 184.0 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain Peptidase_S24 PF00717.18 GAM24731.1 - 2.2e-10 40.0 0.0 3.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 GAM24731.1 - 3.4e-06 26.6 0.0 1.1e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 UPF0233 PF06781.7 GAM24731.1 - 0.004 16.7 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) Pex14_N PF04695.8 GAM24731.1 - 0.021 14.8 1.3 0.031 14.3 0.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.8 GAM24731.1 - 0.038 13.9 0.1 0.054 13.4 0.1 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2207 PF09972.4 GAM24731.1 - 0.13 10.7 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_C78 PF07910.8 GAM24732.1 - 4e-51 173.2 0.1 8.3e-51 172.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase family C78 PhyH PF05721.8 GAM24732.1 - 8.8e-08 32.4 0.0 1.6e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Peptidase_C54 PF03416.14 GAM24732.1 - 0.027 13.6 2.0 0.13 11.3 0.1 2.8 3 0 0 3 3 3 0 Peptidase family C54 PAPS_reduct PF01507.14 GAM24733.1 - 5.5e-19 68.6 0.2 4.5e-13 49.3 0.1 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ABC2_membrane PF01061.19 GAM24734.1 - 7.7e-32 110.1 15.2 1.3e-31 109.4 10.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM24734.1 - 6.4e-27 94.5 0.1 1.3e-26 93.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 GAM24734.1 - 3.9e-07 30.3 0.0 2.6e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM24734.1 - 1.5e-06 27.3 0.1 3.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 GAM24734.1 - 0.00019 20.6 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Med15_fungi PF05397.7 GAM24734.1 - 0.0032 17.4 0.3 0.0061 16.5 0.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit 15 AAA_29 PF13555.1 GAM24734.1 - 0.004 16.6 0.3 0.0093 15.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 GAM24734.1 - 0.0042 16.7 0.0 0.019 14.7 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain NTPase_1 PF03266.10 GAM24734.1 - 0.0052 16.5 0.1 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 GAM24734.1 - 0.0058 16.0 0.0 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM24734.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 GAM24734.1 - 0.019 14.0 1.3 2.1 7.3 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 GAM24734.1 - 0.024 13.6 0.0 0.45 9.4 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 GAM24734.1 - 0.034 13.8 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.20 GAM24734.1 - 0.045 13.2 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 GAM24734.1 - 0.049 13.9 3.3 0.49 10.6 0.5 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM24734.1 - 0.05 13.0 0.9 0.2 11.0 0.4 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 GAM24734.1 - 0.058 13.3 0.1 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM24734.1 - 0.063 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 GAM24734.1 - 0.077 12.9 0.2 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 GAM24734.1 - 0.088 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 GAM24734.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM24734.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM24734.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 GAM24734.1 - 0.15 12.5 0.2 0.73 10.3 0.1 2.1 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 GAM24734.1 - 0.25 10.2 0.6 0.41 9.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SIR2 PF02146.12 GAM24735.1 - 4.8e-57 192.5 0.0 1.3e-56 191.1 0.0 1.8 2 0 0 2 2 2 1 Sir2 family hNIFK_binding PF12196.3 GAM24735.1 - 0.025 13.9 0.3 0.062 12.6 0.2 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK zf-UBP PF02148.14 GAM24735.1 - 0.031 14.4 0.6 0.031 14.4 0.4 3.0 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein TPP_enzyme_M PF00205.17 GAM24735.1 - 0.039 13.7 0.2 0.6 9.8 0.0 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain zf-RING_3 PF14369.1 GAM24735.1 - 3.8 7.5 10.5 1 9.4 1.2 3.5 4 0 0 4 4 4 0 zinc-finger zf-C3HC4_3 PF13920.1 GAM24735.1 - 7.8 6.2 13.4 0.058 13.0 1.4 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Histone PF00125.19 GAM24737.1 - 2e-09 37.4 2.6 0.00046 20.2 0.1 2.5 2 1 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 GAM24737.1 - 0.07 13.2 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone WBP-1 PF11669.3 GAM24738.1 - 0.0096 15.9 0.2 0.025 14.6 0.1 1.7 1 0 0 1 1 1 1 WW domain-binding protein 1 EGF_2 PF07974.8 GAM24738.1 - 0.044 13.9 16.3 0.13 12.4 11.3 1.8 1 0 0 1 1 1 0 EGF-like domain Spore_permease PF03845.8 GAM24738.1 - 0.06 12.0 0.1 0.1 11.1 0.1 1.3 1 0 0 1 1 1 0 Spore germination protein EGF PF00008.22 GAM24738.1 - 1.3 9.0 12.1 3.9 7.5 8.4 1.9 1 0 0 1 1 1 0 EGF-like domain RVT_1 PF00078.22 GAM24739.1 - 5.9e-10 38.8 0.0 1.5e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 GAM24739.1 - 1.8e-05 24.8 3.0 1.9e-05 24.7 1.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Fork_head PF00250.13 GAM24739.1 - 0.0084 16.1 0.1 0.036 14.0 0.0 2.0 2 0 0 2 2 2 1 Fork head domain CAP PF00188.21 GAM24741.1 - 1.5e-18 67.4 0.2 2.6e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rifin_STEVOR PF02009.11 GAM24741.1 - 0.014 15.0 1.4 0.019 14.5 0.9 1.3 1 1 0 1 1 1 0 Rifin/stevor family SOG2 PF10428.4 GAM24741.1 - 0.04 12.5 14.2 0.047 12.3 9.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MDFI PF15316.1 GAM24741.1 - 0.46 10.4 3.8 0.92 9.4 2.6 1.6 1 0 0 1 1 1 0 MyoD family inhibitor Macoilin PF09726.4 GAM24741.1 - 6.1 4.9 10.2 6.9 4.8 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein AAA_11 PF13086.1 GAM24742.1 - 1.8e-20 73.5 0.0 1.5e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.1 GAM24742.1 - 3e-16 59.3 0.1 7.3e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAM24742.1 - 3.1e-12 46.4 0.0 9.9e-12 44.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 GAM24742.1 - 6.7e-06 25.7 0.2 0.08 12.4 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 GAM24742.1 - 5.9e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 GAM24742.1 - 0.003 17.6 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 GAM24742.1 - 0.0069 15.8 0.1 0.015 14.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 GAM24742.1 - 0.0081 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 GAM24742.1 - 0.02 14.1 0.0 0.063 12.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 GAM24742.1 - 0.033 14.3 0.1 0.2 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain Rap_GAP PF02145.10 GAM24743.1 - 1.5e-55 187.4 0.3 5.3e-55 185.7 0.1 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Cellulase PF00150.13 GAM24744.1 - 9.3e-36 123.4 6.1 1.3e-35 122.9 4.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM49 PF09478.5 GAM24744.1 - 6.7e-09 35.7 1.9 6.7e-09 35.7 1.3 3.0 3 1 0 3 3 3 1 Carbohydrate binding domain CBM49 DUF605 PF04652.11 GAM24744.1 - 2.7 7.3 28.0 3.9 6.7 19.4 1.1 1 0 0 1 1 1 0 Vta1 like NIF PF03031.13 GAM24745.1 - 3e-51 173.2 0.4 4.7e-51 172.6 0.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PP2C PF00481.16 GAM24746.1 - 4.6e-62 209.6 0.0 7.9e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM24746.1 - 0.011 15.2 0.1 0.05 12.9 0.0 2.2 2 1 0 2 2 2 0 Protein phosphatase 2C Glyco_hydr_30_2 PF14587.1 GAM24747.1 - 4.3e-15 55.5 7.0 8.2e-15 54.6 4.9 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 GAM24747.1 - 0.00048 19.9 0.3 0.00048 19.9 0.2 1.9 3 0 0 3 3 3 1 Alpha-L-arabinofuranosidase C-terminus Amino_oxidase PF01593.19 GAM24748.1 - 4.3e-65 220.5 0.0 5.2e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM24748.1 - 2.1e-15 56.4 0.1 4.2e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM24748.1 - 1.8e-09 36.9 0.1 2e-06 26.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM24748.1 - 2.3e-07 30.0 0.2 0.01 14.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 GAM24748.1 - 3e-06 26.3 0.0 4.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 GAM24748.1 - 2.4e-05 23.0 0.1 0.005 15.3 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 GAM24748.1 - 0.00022 20.4 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAM24748.1 - 0.00036 20.8 0.7 0.0032 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM24748.1 - 0.00052 19.2 0.0 0.00091 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM24748.1 - 0.0085 16.1 0.3 0.068 13.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM24748.1 - 0.0095 14.8 1.2 1.2 7.8 0.0 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 GAM24748.1 - 0.014 14.4 0.3 0.044 12.8 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 GAM24748.1 - 0.022 14.6 0.3 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2204 PF09970.4 GAM24748.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) NAD_binding_9 PF13454.1 GAM24748.1 - 0.34 10.6 1.4 21 4.8 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Snapin_Pallidin PF14712.1 GAM24750.1 - 5.7e-22 77.8 0.5 5.7e-22 77.8 0.3 1.8 2 0 0 2 2 2 1 Snapin/Pallidin DUF489 PF04356.7 GAM24750.1 - 0.0014 18.2 0.6 0.0024 17.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DUF342 PF03961.8 GAM24750.1 - 0.026 12.9 0.1 0.026 12.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF972 PF06156.8 GAM24750.1 - 0.12 12.7 0.4 0.12 12.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 GAM24750.1 - 0.14 11.9 1.4 0.3 10.9 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sigma70_ner PF04546.8 GAM24750.1 - 1.2 8.6 9.0 23 4.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF3484 PF11983.3 GAM24750.1 - 2.1 9.2 0.1 2.1 9.2 0.0 4.5 3 1 2 5 5 5 0 Domain of unknown function (DUF3484) DUF948 PF06103.6 GAM24750.1 - 2.4 8.0 4.6 1.4 8.7 0.0 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Dynactin_p22 PF07426.6 GAM24750.1 - 3.2 7.0 13.2 1.3 8.2 0.1 3.2 3 0 0 3 3 3 0 Dynactin subunit p22 NifU_N PF01592.11 GAM24751.1 - 1.3e-50 170.6 0.1 1.7e-50 170.1 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Acetyltransf_1 PF00583.19 GAM24753.1 - 3.1e-06 27.1 0.1 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM24753.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM24753.1 - 0.0031 17.6 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM24753.1 - 0.0037 17.1 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 GAM24753.1 - 0.0056 16.5 0.0 0.0099 15.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 GAM24753.1 - 0.014 14.9 0.1 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ACOX PF01756.14 GAM24754.1 - 0.02 14.2 0.3 0.089 12.1 0.2 1.8 2 0 0 2 2 2 0 Acyl-CoA oxidase BRCT PF00533.21 GAM24755.1 - 8e-11 41.9 0.8 1.8e-10 40.8 0.5 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM24755.1 - 0.00011 21.9 0.1 0.00033 20.4 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain CUE PF02845.11 GAM24755.1 - 0.013 15.0 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 CUE domain Prp19_bind PF06991.6 GAM24755.1 - 2.1 7.5 29.2 3.7 6.7 20.2 1.4 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain V_ATPase_I PF01496.14 GAM24755.1 - 5 4.8 7.7 7.1 4.3 5.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rap_GAP PF02145.10 GAM24756.1 - 4e-54 182.8 1.0 7.3e-54 182.0 0.7 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Peptidase_S49_N PF08496.5 GAM24756.1 - 0.15 11.8 4.4 0.59 9.9 3.0 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FNIP PF05725.7 GAM24759.1 - 7.7e-37 124.9 14.7 2e-11 43.6 0.0 6.4 4 2 1 5 5 5 5 FNIP Repeat AAA_22 PF13401.1 GAM24760.1 - 0.036 14.2 0.1 0.082 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA12 PF10443.4 GAM24760.1 - 0.051 12.0 0.0 0.069 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein FAD_binding_7 PF03441.9 GAM24760.1 - 0.055 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase AftA_C PF12249.3 GAM24760.1 - 0.093 12.1 0.2 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Arabinofuranosyltransferase A C terminal Elong_Iki1 PF10483.4 GAM24760.1 - 0.1 11.9 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_16 PF13191.1 GAM24760.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain tRNA-synt_1b PF00579.20 GAM24761.1 - 1.2e-60 205.0 0.0 1.5e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RCC1 PF00415.13 GAM24762.1 - 4.9e-78 257.1 18.7 4.9e-15 55.4 0.2 8.8 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM24762.1 - 2.1e-40 135.4 25.7 6.8e-07 28.7 0.3 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat DUF2404 PF10296.4 GAM24762.1 - 0.11 12.6 0.0 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) CDC45 PF02724.9 GAM24762.1 - 3.8 5.4 10.4 0.36 8.8 4.1 1.4 2 0 0 2 2 2 0 CDC45-like protein DUF4614 PF15391.1 GAM24762.1 - 5.9 6.6 20.8 0.15 11.8 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) RhoGEF PF00621.15 GAM24763.1 - 2e-41 141.8 2.7 4.1e-41 140.8 1.9 1.5 1 0 0 1 1 1 1 RhoGEF domain EMA PF02488.10 GAM24763.1 - 0.0019 17.7 0.2 0.0033 16.9 0.2 1.3 1 0 0 1 1 1 1 Merozoite Antigen SOXp PF12336.3 GAM24763.1 - 0.068 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 SOX transcription factor DUF1870 PF08965.5 GAM24763.1 - 0.078 12.6 0.6 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1870) FNIP PF05725.7 GAM24764.1 - 5.5e-72 237.5 6.7 1e-12 47.7 0.1 10.4 6 3 3 10 10 10 9 FNIP Repeat Utp21 PF04192.7 GAM24765.1 - 1e-46 158.9 11.4 2.5e-45 154.4 6.8 2.5 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 GAM24765.1 - 1.5e-21 75.4 16.7 2e-05 24.2 0.1 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat Alpha_E2_glycop PF00943.14 GAM24765.1 - 0.12 10.9 0.4 0.28 9.7 0.1 1.6 2 0 0 2 2 2 0 Alphavirus E2 glycoprotein PSI PF01437.20 GAM24766.1 - 4.1e-06 26.8 11.8 7.1e-06 26.0 8.2 1.4 1 0 0 1 1 1 1 Plexin repeat DUF912 PF06024.7 GAM24766.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PLDc_2 PF13091.1 GAM24768.1 - 2e-12 46.9 0.0 8e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM24768.1 - 0.00016 21.3 0.6 0.58 10.0 0.3 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif GST_N PF02798.15 GAM24769.1 - 2e-11 43.9 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM24769.1 - 2.7e-10 40.0 0.0 1.3e-09 37.8 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM24769.1 - 3e-06 27.6 0.0 4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM24769.1 - 9.4e-06 25.4 0.1 2.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM24769.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ins134_P3_kin PF05770.6 GAM24770.1 - 1.4e-61 208.1 0.9 1.6e-61 207.9 0.6 1.0 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase RimK PF08443.6 GAM24770.1 - 0.00047 19.6 0.1 0.002 17.6 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 GAM24770.1 - 0.011 15.6 0.3 0.031 14.1 0.2 1.7 1 1 0 1 1 1 0 ATP-grasp domain Pkinase PF00069.20 GAM24771.1 - 5.1e-59 199.5 0.2 8.7e-59 198.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24771.1 - 1.5e-35 122.5 0.0 2.8e-35 121.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24771.1 - 4.2e-13 48.9 0.0 8.7e-13 47.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 GAM24771.1 - 0.004 16.9 0.0 0.38 10.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM24771.1 - 0.046 13.0 0.7 0.43 9.8 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Sporozoite_P67 PF05642.6 GAM24771.1 - 1 7.1 9.7 1.4 6.6 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TSA PF03249.8 GAM24771.1 - 4.9 5.5 10.8 24 3.3 5.7 2.0 2 0 0 2 2 2 0 Type specific antigen ABC_tran PF00005.22 GAM24772.1 - 1.2e-27 96.8 0.0 2.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM24772.1 - 7e-09 36.0 1.8 2.3e-06 27.8 0.1 2.2 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 GAM24772.1 - 0.00082 19.2 0.4 0.015 15.2 0.2 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAM24772.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM24772.1 - 0.002 18.1 0.2 0.0033 17.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 GAM24772.1 - 0.0055 15.7 0.0 0.0083 15.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 GAM24772.1 - 0.016 14.8 0.9 1 9.0 0.1 2.3 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 GAM24772.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 GAM24772.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 GAM24772.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.17 GAM24774.1 - 6.1e-09 34.9 0.3 7.2e-09 34.7 0.2 1.0 1 0 0 1 1 1 1 Cullin family Fibrillarin PF01269.12 GAM24776.1 - 3.7e-102 340.1 0.0 4.3e-102 339.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 GAM24776.1 - 0.00077 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 GAM24776.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Na_Ca_ex PF01699.19 GAM24777.1 - 2.5e-13 49.8 26.5 1.5e-07 31.1 10.6 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein SH3_2 PF07653.12 GAM24778.1 - 1.9e-14 52.9 0.1 2.9e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAM24778.1 - 7.7e-13 47.8 0.3 1.2e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM24778.1 - 3.5e-09 35.8 0.2 5.2e-09 35.3 0.2 1.3 1 0 0 1 1 1 1 SH3 domain DZR PF12773.2 GAM24778.1 - 0.0017 18.1 0.6 0.0031 17.2 0.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM24778.1 - 0.012 14.7 2.6 0.019 14.1 1.8 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM24778.1 - 0.013 14.9 4.8 0.022 14.2 3.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 GAM24778.1 - 0.17 11.6 1.1 0.26 10.9 0.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 GAM24778.1 - 0.69 8.0 21.1 0.75 7.9 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1421 PF07223.6 GAM24778.1 - 2.5 7.7 44.3 3.3 7.4 30.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) CCDC92 PF14916.1 GAM24780.1 - 0.0085 15.6 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Tetraspannin PF00335.15 GAM24781.1 - 7.3e-29 100.6 15.9 9e-29 100.3 11.0 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2809 PF10990.3 GAM24781.1 - 0.0033 17.8 2.2 0.0033 17.8 1.5 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2809) SPC12 PF06645.8 GAM24781.1 - 0.054 13.3 0.4 0.054 13.3 0.3 2.3 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3042 PF11240.3 GAM24781.1 - 0.21 11.4 2.7 8.5 6.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) EcsB PF05975.7 GAM24781.1 - 1.6 7.1 0.0 1.6 7.1 0.0 2.3 2 1 1 3 3 3 0 Bacterial ABC transporter protein EcsB ABC2_membrane_2 PF12679.2 GAM24781.1 - 5.3 5.8 8.8 0.06 12.1 1.0 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Herpes_UL43 PF05072.8 GAM24781.1 - 9.8 4.8 11.6 2.4 6.8 0.2 2.2 1 1 1 2 2 2 0 Herpesvirus UL43 protein Abhydrolase_6 PF12697.2 GAM24782.1 - 5.4e-29 101.6 0.0 7e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM24782.1 - 2.3e-15 56.7 0.0 9.4e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM24782.1 - 1.1e-12 47.9 0.0 3.5e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM24782.1 - 0.0023 17.7 0.1 0.0063 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 GAM24782.1 - 0.0044 15.5 0.0 0.0054 15.2 0.0 1.5 1 1 0 1 1 1 1 Ndr family UPF0227 PF05728.7 GAM24782.1 - 0.03 14.0 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF915 PF06028.6 GAM24782.1 - 0.037 13.1 0.0 0.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 GAM24782.1 - 0.043 13.2 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Phage_P2_GpU PF06995.6 GAM24782.1 - 0.13 11.6 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Phage P2 GpU DNA_topoisoIV PF00521.15 GAM24783.1 - 1.4e-110 370.1 16.4 2.1e-84 283.8 0.0 2.7 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 GAM24783.1 - 1.2e-28 99.4 0.4 1.2e-28 99.4 0.3 2.6 3 0 0 3 3 3 1 DNA gyrase B Toprim PF01751.17 GAM24783.1 - 2.5e-11 43.4 0.0 1.4e-10 41.0 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 GAM24783.1 - 3.8e-08 33.0 0.0 9.1e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cornichon PF03311.9 GAM24784.1 - 9.9e-35 119.4 16.1 1.1e-34 119.3 11.2 1.0 1 0 0 1 1 1 1 Cornichon protein Bac_export_2 PF01312.14 GAM24784.1 - 0.54 9.0 5.9 0.57 9.0 4.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Arm PF00514.18 GAM24785.1 - 4.5e-05 23.1 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat HMA PF00403.21 GAM24785.1 - 0.003 17.6 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain FNIP PF05725.7 GAM24786.1 - 1.7e-58 194.2 11.7 3.2e-12 46.1 0.0 9.9 6 3 4 11 11 11 10 FNIP Repeat DUF1769 PF08588.5 GAM24786.1 - 6.4e-06 26.0 0.2 1.6 8.7 0.0 4.8 3 1 2 5 5 5 2 Protein of unknown function (DUF1769) Meth_synt_2 PF01717.13 GAM24787.1 - 4.7e-146 485.8 0.0 9.3e-138 458.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 GAM24787.1 - 2.3e-107 358.8 0.0 9.3e-96 320.7 0.0 4.0 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain vWA-TerF-like PF10138.4 GAM24788.1 - 1.1e-13 51.5 0.1 1.5e-13 51.0 0.1 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 GAM24788.1 - 2.6e-09 37.4 0.3 3.8e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM24788.1 - 8.6e-09 35.3 0.1 1.1e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain CTP_transf_1 PF01148.15 GAM24789.1 - 4.7e-66 223.0 29.1 6.4e-66 222.6 20.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family RP-C_C PF11800.3 GAM24789.1 - 0.13 11.8 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Ank_2 PF12796.2 GAM24790.1 - 6.9e-09 35.9 0.1 7.2e-05 23.0 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM24790.1 - 2.5e-06 27.1 1.1 1.2 9.6 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.25 GAM24790.1 - 0.00031 20.3 0.4 13 5.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAM24790.1 - 0.0006 20.2 0.1 1.3 9.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM24790.1 - 0.00068 19.8 0.2 3 8.2 0.0 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) SPRY PF00622.23 GAM24791.1 - 4e-17 62.4 0.4 7.9e-17 61.5 0.3 1.5 1 0 0 1 1 1 1 SPRY domain DEAD PF00270.24 GAM24791.1 - 4.4e-15 55.5 0.0 4.4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_3 PF13302.1 GAM24792.1 - 5e-13 49.4 0.0 6.7e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM24792.1 - 3.7e-08 33.4 0.1 4.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM24792.1 - 0.0051 16.7 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM24792.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family zf-C2HC5 PF06221.8 GAM24793.1 - 5.1e-18 64.5 7.7 1e-17 63.5 5.3 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type NAGidase PF07555.8 GAM24793.1 - 1.3e-08 34.1 0.0 4.5e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase UvrD-helicase PF00580.16 GAM24793.1 - 0.00012 21.5 2.7 0.00012 21.5 1.9 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Glyco_hydro_97 PF10566.4 GAM24793.1 - 0.00053 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase 97 PWI PF01480.12 GAM24793.1 - 2 8.5 6.7 0.58 10.2 0.1 3.5 4 1 0 4 4 4 0 PWI domain SH3_6 PF12913.2 GAM24795.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type SMC_N PF02463.14 GAM24797.1 - 3.7e-49 166.9 64.1 1.9e-48 164.6 44.4 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 GAM24797.1 - 2.1e-22 79.3 2.7 4.4e-22 78.3 0.1 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 GAM24797.1 - 1.5e-10 41.7 30.8 1.5e-10 41.7 21.3 6.8 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 GAM24797.1 - 1.6e-09 38.1 30.7 2.9e-06 27.4 5.4 4.3 4 1 1 5 5 5 2 AAA domain AAA_29 PF13555.1 GAM24797.1 - 0.00016 21.1 0.0 0.00047 19.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-Q PF13094.1 GAM24797.1 - 0.0099 15.9 14.1 0.0099 15.9 9.8 7.1 4 1 3 7 7 7 2 CENP-Q, a CENPA-CAD centromere complex subunit DUF1212 PF06738.7 GAM24797.1 - 1.9 7.9 3.2 6 6.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1212) Clathrin PF00637.15 GAM24798.1 - 1.9e-21 76.1 3.4 1.9e-21 76.1 2.3 4.1 2 1 2 4 4 4 1 Region in Clathrin and VPS Vps39_2 PF10367.4 GAM24798.1 - 2.6e-07 30.8 3.1 6.6e-07 29.4 2.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.27 GAM24798.1 - 0.00031 20.4 0.7 0.11 12.4 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 GAM24798.1 - 0.00062 19.8 2.5 0.0017 18.4 1.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 GAM24798.1 - 0.0036 17.1 6.7 0.0036 17.1 4.7 2.5 2 1 1 3 3 3 1 Ring finger domain RXT2_N PF08595.6 GAM24798.1 - 0.016 15.0 8.9 0.039 13.7 6.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-Apc11 PF12861.2 GAM24798.1 - 0.02 14.7 0.9 0.049 13.4 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 GAM24798.1 - 0.068 12.9 4.3 0.23 11.2 3.0 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 GAM24798.1 - 0.18 11.5 5.1 0.15 11.8 1.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Vps39_1 PF10366.4 GAM24798.1 - 0.36 10.8 7.3 0.4 10.7 0.2 3.2 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 BSP_II PF05432.6 GAM24798.1 - 2.5 7.3 21.4 4.7 6.3 14.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-C3HC4 PF00097.20 GAM24798.1 - 4.1 7.1 8.8 7.1 6.3 2.9 2.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.7 GAM24799.1 - 5.6e-117 381.5 37.5 1.8e-14 53.3 0.1 11.8 8 2 2 12 12 12 11 FNIP Repeat LRR_5 PF13306.1 GAM24799.1 - 1.2e-05 24.9 0.3 0.54 9.9 0.0 3.9 3 0 0 3 3 3 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 GAM24799.1 - 0.015 15.2 13.8 32 4.5 0.0 7.8 6 2 4 10 10 10 0 Protein of unknown function (DUF1769) Pyr_redox_dim PF02852.17 GAM24800.1 - 2.4e-39 133.7 0.0 5.5e-39 132.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAM24800.1 - 6.3e-37 127.4 10.7 1.4e-36 126.2 6.6 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM24800.1 - 2.3e-21 75.9 16.4 2.9e-20 72.4 1.1 4.0 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM24800.1 - 1.2e-10 41.0 6.0 9e-10 38.1 0.3 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 GAM24800.1 - 1.4e-10 41.5 2.4 1.3e-05 25.3 0.3 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM24800.1 - 3.6e-06 26.9 6.7 0.00036 20.4 1.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 GAM24800.1 - 5.6e-06 25.0 11.4 0.00016 20.2 0.3 4.0 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.17 GAM24800.1 - 5.8e-06 25.4 10.3 0.00019 20.4 3.7 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 GAM24800.1 - 3.7e-05 22.7 3.9 3.7e-05 22.7 2.7 3.1 3 0 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 GAM24800.1 - 8.6e-05 21.5 2.9 0.0015 17.5 0.1 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 GAM24800.1 - 0.00058 19.5 1.3 0.0016 18.1 0.5 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 GAM24800.1 - 0.00077 19.0 3.0 0.014 14.9 0.1 2.9 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAM24800.1 - 0.00085 18.3 0.7 0.023 13.6 0.0 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 GAM24800.1 - 0.002 17.2 2.6 0.002 17.2 1.8 3.1 2 1 1 3 3 3 1 Thi4 family XdhC_C PF13478.1 GAM24800.1 - 0.0041 17.4 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain ChuX_HutX PF06228.8 GAM24800.1 - 0.029 13.7 0.1 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX DAO PF01266.19 GAM24800.1 - 0.037 12.9 25.8 0.24 10.2 2.2 4.0 2 2 2 4 4 4 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 GAM24800.1 - 0.043 12.8 3.5 0.91 8.5 0.2 2.9 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 GAM24800.1 - 0.24 10.4 15.5 0.48 9.4 1.8 3.3 3 1 0 3 3 3 0 FAD binding domain DUF3430 PF11912.3 GAM24801.1 - 1.1e-08 35.1 14.5 2e-08 34.3 10.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 GAM24801.1 - 0.0032 17.4 13.4 0.39 10.7 0.4 4.0 2 2 1 3 3 3 3 Protein of unknown function (DUF3586) Anophelin PF10731.4 GAM24801.1 - 0.025 14.6 1.0 0.055 13.5 0.7 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito PH PF00169.24 GAM24802.1 - 2.6e-19 69.3 1.9 5.6e-19 68.2 1.3 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM24802.1 - 1.2e-07 31.9 6.9 1.9e-06 28.1 0.3 2.8 2 1 1 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 GAM24802.1 - 1.8e-05 24.5 0.4 3.2e-05 23.7 0.3 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM24802.1 - 0.00068 19.6 1.1 0.0018 18.3 0.8 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.5 GAM24802.1 - 0.00074 19.4 0.1 0.092 12.6 0.0 2.3 1 1 1 2 2 2 1 Plant pleckstrin homology-like region PH_9 PF15410.1 GAM24802.1 - 0.011 15.8 2.0 0.24 11.5 1.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_7 PF15408.1 GAM24802.1 - 0.014 15.2 0.1 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain PRP38 PF03371.10 GAM24804.1 - 9.1e-59 197.9 0.2 1.2e-58 197.5 0.1 1.1 1 0 0 1 1 1 1 PRP38 family ANAPC15 PF15243.1 GAM24805.1 - 0.028 14.4 0.8 0.028 14.4 0.5 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 F-box PF00646.28 GAM24806.1 - 0.00031 20.3 0.1 0.0023 17.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM24806.1 - 0.00074 19.2 0.8 0.0024 17.5 0.3 2.0 2 0 0 2 2 2 1 F-box-like Ank_2 PF12796.2 GAM24807.1 - 9e-48 160.5 22.9 1.1e-10 41.6 0.0 5.3 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM24807.1 - 5.7e-30 102.6 11.6 0.0024 18.0 0.0 11.9 3 3 9 12 12 12 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM24807.1 - 1.6e-28 98.5 11.5 1.2e-07 32.0 0.0 7.8 5 3 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24807.1 - 2.1e-22 76.9 14.9 0.054 13.7 0.0 11.6 8 3 5 13 13 13 6 Ankyrin repeat Ank PF00023.25 GAM24807.1 - 6.5e-20 69.8 3.3 0.17 11.7 0.0 10.8 9 2 2 11 11 11 5 Ankyrin repeat DUF2846 PF11008.3 GAM24807.1 - 0.095 12.5 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) DUF4397 PF14344.1 GAM24808.1 - 4.2e-11 43.2 0.1 1.6e-09 38.1 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4397) MPC PF03650.8 GAM24809.1 - 2.9e-22 78.8 0.5 3.1e-22 78.7 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MPC PF03650.8 GAM24810.1 - 2.7e-14 53.1 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ANTH PF07651.11 GAM24811.1 - 1.7e-49 168.0 3.5 1.7e-49 168.0 2.4 2.1 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 GAM24811.1 - 3.5e-05 23.6 0.1 8.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ENTH domain RRM_1 PF00076.17 GAM24812.1 - 1.1e-25 88.9 4.5 1.6e-09 37.2 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM24812.1 - 2.6e-16 59.3 0.2 7.8e-06 25.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM24812.1 - 8.6e-13 47.9 2.4 3.9e-08 33.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cofilin_ADF PF00241.15 GAM24813.1 - 4.5e-14 52.4 0.0 5.5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_6 PF13405.1 GAM24814.1 - 6.5e-16 56.7 2.7 3.8e-06 26.3 0.1 4.0 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 GAM24814.1 - 3.8e-15 55.7 0.3 9e-08 32.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM24814.1 - 3.8e-14 50.8 0.2 4.6e-06 25.5 0.0 4.1 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 GAM24814.1 - 8.6e-12 44.4 0.3 4.6e-06 26.1 0.0 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM24814.1 - 8.5e-07 28.0 0.4 0.014 14.7 0.1 3.3 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 GAM24814.1 - 0.00013 21.4 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_9 PF14658.1 GAM24814.1 - 0.00045 20.0 0.0 0.14 12.1 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 GAM24814.1 - 0.0061 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand DUF853 PF05872.7 GAM24814.1 - 0.013 13.8 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) EF-hand_like PF09279.6 GAM24814.1 - 0.02 14.8 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Caleosin PF05042.8 GAM24814.1 - 0.098 12.2 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 Caleosin related protein DAP_epimerase PF01678.14 GAM24815.1 - 6.4e-24 84.1 4.8 3.8e-15 55.8 0.0 3.1 4 0 0 4 4 4 2 Diaminopimelate epimerase PagP PF07017.6 GAM24815.1 - 0.11 11.7 0.2 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Zn_Tnp_IS1595 PF12760.2 GAM24816.1 - 0.034 13.9 19.3 0.55 10.0 3.9 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 GAM24816.1 - 1.4 8.6 14.7 2.6 7.7 2.7 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L37ae PF01780.14 GAM24816.1 - 2.8 7.8 10.5 8.3 6.3 1.4 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF3672 PF12421.3 GAM24817.1 - 0.56 10.3 4.4 1 9.5 3.0 1.5 1 1 0 1 1 1 0 Fibronectin type III protein DUF2678 PF10856.3 GAM24818.1 - 2.3e-11 43.4 0.4 3.4e-11 42.9 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF4131 PF13567.1 GAM24818.1 - 0.00014 21.3 0.8 0.00019 20.8 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Acyl_transf_3 PF01757.17 GAM24818.1 - 0.0018 17.2 2.6 0.0023 16.8 1.8 1.1 1 0 0 1 1 1 1 Acyltransferase family AA_permease_2 PF13520.1 GAM24818.1 - 0.0019 16.8 1.3 0.0025 16.4 0.9 1.1 1 0 0 1 1 1 1 Amino acid permease TauE PF01925.14 GAM24818.1 - 0.014 14.8 2.6 0.018 14.4 1.8 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2721 PF11026.3 GAM24818.1 - 0.025 14.2 1.0 0.025 14.2 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) BacA PF02673.13 GAM24818.1 - 0.026 13.7 1.2 0.038 13.1 0.9 1.3 1 1 0 1 1 1 0 Bacitracin resistance protein BacA CopD PF05425.8 GAM24818.1 - 0.056 13.6 0.6 0.089 13.0 0.0 1.6 2 0 0 2 2 2 0 Copper resistance protein D DUF4010 PF13194.1 GAM24818.1 - 0.13 11.5 1.6 1.2 8.3 1.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4010) DUF3290 PF11694.3 GAM24818.1 - 0.14 11.9 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF2427 PF10348.4 GAM24818.1 - 0.16 11.5 1.6 0.29 10.7 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Bac_Ubq_Cox PF01654.12 GAM24818.1 - 0.18 10.1 2.2 0.3 9.4 1.6 1.3 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase YwiC PF14256.1 GAM24818.1 - 0.19 11.8 2.9 0.28 11.2 2.0 1.2 1 0 0 1 1 1 0 YwiC-like protein YfhO PF09586.5 GAM24818.1 - 0.33 8.9 2.0 0.4 8.6 1.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO MFS_1 PF07690.11 GAM24818.1 - 1.8 7.1 8.5 3.8 6.1 6.0 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily Sel1 PF08238.7 GAM24819.1 - 5.2e-28 96.8 18.6 7.7e-06 26.3 1.3 6.4 6 0 0 6 6 6 5 Sel1 repeat Vps23_core PF09454.5 GAM24819.1 - 0.003 17.1 0.1 0.017 14.7 0.0 2.2 2 1 1 3 3 3 1 Vps23 core domain TPR_16 PF13432.1 GAM24819.1 - 0.047 14.3 15.6 1.2 9.8 0.7 4.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Coiled PF05710.7 GAM24820.1 - 1.6 9.2 11.9 2.6 8.5 8.2 1.4 1 1 0 1 1 1 0 Coiled coil F-box PF00646.28 GAM24821.1 - 0.0099 15.5 0.6 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 F-box domain CHASE3 PF05227.8 GAM24822.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 CHASE3 domain Gas_vesicle PF00741.13 GAM24823.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.2 1 0 0 1 1 1 0 Gas vesicle protein Coiled PF05710.7 GAM24823.1 - 1.6 9.2 8.7 2.9 8.4 6.1 1.5 1 1 0 1 1 1 0 Coiled coil DUF1786 PF08735.5 GAM24824.1 - 0.048 12.8 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) zf-ribbon_3 PF13248.1 GAM24825.1 - 0.32 10.2 5.0 0.52 9.5 3.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain RRM_5 PF13893.1 GAM24826.1 - 9.9e-05 22.1 0.1 0.00043 20.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SICA_C PF12879.2 GAM24826.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.5 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain RRM_1 PF00076.17 GAM24826.1 - 0.093 12.3 0.0 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.15 GAM24827.1 - 1.6e-06 26.7 0.9 3.9e-06 25.4 0.6 1.6 1 1 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 GAM24827.1 - 0.00081 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT PF02985.17 GAM24827.1 - 0.15 12.2 2.4 59 4.1 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat TPR_17 PF13431.1 GAM24828.1 - 0.00016 21.5 0.0 0.025 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM24828.1 - 0.00016 21.2 0.0 1.7 8.3 0.0 3.4 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 GAM24828.1 - 0.00025 20.7 0.1 0.53 10.3 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24828.1 - 0.002 18.0 0.0 4.4 7.3 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM24828.1 - 0.0064 16.0 0.4 28 4.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24828.1 - 0.05 14.2 0.0 53 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24828.1 - 0.086 12.6 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat REJ PF02010.10 GAM24829.1 - 3.6e-55 187.0 16.8 1.1e-50 172.2 3.2 2.9 2 1 1 3 3 3 2 REJ domain Glycos_transf_2 PF00535.21 GAM24829.1 - 3.4e-26 91.9 0.1 6.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM24829.1 - 1.4e-14 54.5 1.2 6.9e-14 52.1 0.2 2.5 3 1 0 3 3 2 1 Glycosyltransferase like family 2 Glyco_trans_4_4 PF13579.1 GAM24829.1 - 1.4e-13 51.2 0.5 2.8e-13 50.3 0.0 1.8 2 0 0 2 2 1 1 Glycosyl transferase 4-like domain GPS PF01825.16 GAM24829.1 - 2.4e-12 46.7 7.1 5.3e-12 45.6 4.9 1.6 1 0 0 1 1 1 1 Latrophilin/CL-1-like GPS domain TIG PF01833.19 GAM24829.1 - 3.3e-12 46.2 0.5 3.3e-12 46.2 0.4 3.7 4 0 0 4 4 4 1 IPT/TIG domain Glyco_tranf_2_2 PF10111.4 GAM24829.1 - 9.1e-12 44.6 0.0 4.5e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_4 PF13439.1 GAM24829.1 - 0.00013 21.7 0.1 0.0012 18.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.15 GAM24829.1 - 0.00027 20.4 0.1 0.57 9.5 0.0 3.3 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_21 PF13506.1 GAM24829.1 - 0.00051 19.3 0.1 0.0012 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1510 PF07423.6 GAM24829.1 - 0.00081 18.8 4.7 0.00081 18.8 3.2 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF1510) Glyco_trans_4_2 PF13477.1 GAM24829.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like TMEM154 PF15102.1 GAM24829.1 - 0.007 16.0 0.2 0.49 10.0 0.0 3.0 2 0 0 2 2 2 1 TMEM154 protein family Glyco_transf_5 PF08323.6 GAM24829.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain EphA2_TM PF14575.1 GAM24829.1 - 0.023 15.0 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FlgD_ig PF13860.1 GAM24829.1 - 0.024 14.3 0.0 0.07 12.8 0.0 1.8 1 0 0 1 1 1 0 FlgD Ig-like domain DUF1191 PF06697.7 GAM24829.1 - 0.025 13.4 0.1 0.048 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) IQ PF00612.22 GAM24829.1 - 0.057 13.0 3.0 0.14 11.8 2.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Glyco_trans_2_3 PF13632.1 GAM24829.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family group 2 OAD_gamma PF04277.8 GAM24829.1 - 0.083 13.2 4.7 0.26 11.6 3.3 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Glyco_transf_7C PF02709.9 GAM24829.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Ycf1 PF05758.7 GAM24829.1 - 0.52 7.9 2.8 0.75 7.4 2.0 1.1 1 0 0 1 1 1 0 Ycf1 AA_permease_2 PF13520.1 GAM24830.1 - 2.8e-30 105.2 59.2 3.6e-30 104.8 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM24830.1 - 3.4e-30 104.8 51.4 4.6e-30 104.4 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease FNIP PF05725.7 GAM24831.1 - 1.8e-39 133.3 22.7 9.8e-14 51.0 0.4 7.3 5 2 2 7 7 7 7 FNIP Repeat ECH PF00378.15 GAM24834.1 - 3.5e-67 226.1 1.0 4.8e-67 225.6 0.7 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 GAM24834.1 - 0.014 15.2 1.6 0.4 10.4 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S49 Cytochrom_C550 PF14495.1 GAM24834.1 - 0.079 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c-550 domain ECH_C PF13766.1 GAM24834.1 - 0.097 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Fringe PF02434.11 GAM24835.1 - 4.5e-14 52.2 1.5 4.5e-13 48.9 1.0 2.0 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 GAM24835.1 - 0.00018 21.1 0.2 0.00054 19.6 0.0 1.8 2 0 0 2 2 2 1 Galactosyltransferase SpoU_methylase PF00588.14 GAM24836.1 - 1.4e-27 96.3 0.0 2.8e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family DUF531 PF04407.7 GAM24836.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF531) Ima1_N PF09779.4 GAM24836.1 - 0.17 12.3 1.2 0.33 11.4 0.9 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain Hexapep PF00132.19 GAM24838.1 - 9.8e-16 56.4 5.6 6.1e-07 28.6 0.6 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM24838.1 - 1.7e-07 30.6 6.2 0.00093 18.7 0.0 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Coiled PF05710.7 GAM24839.1 - 0.55 10.7 10.7 0.88 10.0 7.4 1.4 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.7 GAM24840.1 - 0.00049 20.5 7.7 0.00062 20.1 5.3 1.2 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.7 GAM24841.1 - 0.1 13.0 8.0 0.2 12.1 5.6 1.5 1 1 0 1 1 1 0 Coiled coil RVT_1 PF00078.22 GAM24842.1 - 1e-12 47.8 1.6 8.6e-12 44.8 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 GAM24842.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger RVT_2 PF07727.9 GAM24842.1 - 0.52 9.2 3.9 0.75 8.7 0.2 2.8 2 2 2 4 4 4 0 Reverse transcriptase (RNA-dependent DNA polymerase) FH2 PF02181.18 GAM24844.1 - 1.1e-79 268.0 7.4 1.1e-79 268.0 5.1 2.6 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 GAM24844.1 - 1.1e-41 142.2 0.3 1.1e-41 142.2 0.2 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 GAM24844.1 - 5.7e-21 74.8 0.2 2.1e-20 72.9 0.2 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain Glyco_hydro_71 PF03659.9 GAM24845.1 - 8.2e-22 77.2 5.8 2.9e-21 75.3 4.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 Cellulase PF00150.13 GAM24846.1 - 1.8e-38 132.4 0.0 2.6e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TFIIA PF03153.8 GAM24846.1 - 1.9 8.3 9.6 2.6 7.8 6.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_3 PF12698.2 GAM24847.1 - 0.23 10.4 0.7 0.26 10.2 0.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.27 GAM24848.1 - 8e-10 38.2 6.9 7e-08 32.0 0.5 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat CRT10 PF08728.5 GAM24848.1 - 1.2e-05 23.5 0.3 1.2e-05 23.5 0.2 3.6 2 1 0 3 3 3 2 CRT10 Nup160 PF11715.3 GAM24848.1 - 0.0024 16.1 0.3 0.0049 15.0 0.2 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Dicty_REP PF05086.7 GAM24848.1 - 0.0085 13.9 5.2 0.012 13.3 3.6 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein BTV_NS2 PF04514.7 GAM24848.1 - 0.0085 15.0 11.8 0.013 14.4 8.2 1.2 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 DUF775 PF05603.7 GAM24848.1 - 0.055 12.9 1.5 2.4 7.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Cwf_Cwc_15 PF04889.7 GAM24848.1 - 0.44 10.2 15.7 0.63 9.7 10.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAM24848.1 - 1.4 6.7 15.2 1.8 6.3 10.5 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM24848.1 - 2.7 6.3 16.3 3.6 5.9 11.3 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 GAM24848.1 - 4.7 6.4 15.0 6.8 5.8 10.4 1.2 1 0 0 1 1 1 0 SDA1 MYEOV2 PF15004.1 GAM24849.1 - 0.011 16.2 4.4 0.011 16.2 3.0 2.0 1 1 1 2 2 2 0 Myeloma-overexpressed-like PUF PF00806.14 GAM24851.1 - 2.8e-56 183.9 11.5 5e-09 35.1 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.19 GAM24851.1 - 0.00038 20.0 3.5 0.001 18.6 2.4 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNB PF00773.14 GAM24852.1 - 2.1e-28 99.5 7.9 5.3e-28 98.2 5.5 1.7 1 0 0 1 1 1 1 RNB domain AAA_11 PF13086.1 GAM24852.1 - 2e-21 76.6 0.0 4.4e-19 69.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 GAM24852.1 - 8.6e-11 41.5 0.0 2.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM24852.1 - 2.1e-05 24.1 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 GAM24852.1 - 0.00031 21.1 0.1 0.004 17.5 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 GAM24852.1 - 0.0025 18.6 0.4 0.011 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Syntaxin PF00804.20 GAM24852.1 - 0.003 17.6 0.9 0.003 17.6 0.6 2.4 2 0 0 2 2 2 1 Syntaxin AAA_30 PF13604.1 GAM24852.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 GAM24852.1 - 0.047 12.9 0.0 0.15 11.2 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 GAM24852.1 - 0.054 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PH PF00169.24 GAM24853.1 - 3.2e-14 52.9 0.0 1.4e-13 50.9 0.0 2.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM24853.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM24853.1 - 0.012 15.8 0.1 2.2 8.4 0.0 3.1 2 0 0 2 2 2 0 Pleckstrin homology domain DDE_Tnp_IS240 PF13610.1 GAM24853.1 - 1.5 8.7 5.7 0.24 11.3 0.3 2.3 2 0 0 2 2 2 0 DDE domain DUF1674 PF07896.7 GAM24854.1 - 1.3e-18 66.9 4.5 2.1e-18 66.2 3.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) YARHG PF13308.1 GAM24854.1 - 0.0088 15.5 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 YARHG domain PspB PF06667.7 GAM24854.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Phage shock protein B BBS2_C PF14782.1 GAM24854.1 - 0.14 10.6 0.0 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Ank_2 PF12796.2 GAM24855.1 - 0.0011 19.3 0.0 0.06 13.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM24855.1 - 0.018 15.2 0.3 23 5.4 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM24855.1 - 0.025 14.7 3.4 18 5.9 0.0 5.5 5 0 0 5 5 5 0 Ankyrin repeat CbiA PF01656.18 GAM24856.1 - 3.2e-26 91.9 0.0 4.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM24856.1 - 1.9e-16 60.4 0.0 2.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 GAM24856.1 - 5.7e-09 35.4 0.0 1.1e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 GAM24856.1 - 7.5e-07 28.4 0.3 3e-06 26.5 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 GAM24856.1 - 8.6e-05 21.8 0.1 0.16 11.1 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 GAM24856.1 - 0.001 18.5 0.7 0.81 9.1 0.2 2.4 2 1 0 2 2 2 2 SRP54-type protein, GTPase domain YhjQ PF06564.7 GAM24856.1 - 0.0081 15.5 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 1 YhjQ protein AAA_24 PF13479.1 GAM24856.1 - 0.14 11.6 0.3 0.31 10.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 GAM24856.1 - 0.18 10.9 0.9 0.32 10.0 0.6 1.5 1 1 0 1 1 1 0 KaiC Ras PF00071.17 GAM24857.1 - 1.2e-64 216.5 0.4 1.5e-64 216.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24857.1 - 7.1e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24857.1 - 5.2e-16 58.3 0.0 6.5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM24857.1 - 3e-08 33.0 0.0 3.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM24857.1 - 3.9e-06 26.4 0.2 8.1e-06 25.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM24857.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM24857.1 - 0.00079 18.6 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAM24857.1 - 0.0019 18.3 0.0 0.003 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 GAM24857.1 - 0.01 16.0 0.0 0.41 10.8 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 GAM24857.1 - 0.022 13.9 0.0 0.059 12.5 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM24857.1 - 0.031 13.7 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM24857.1 - 0.034 14.1 0.1 0.092 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 GAM24857.1 - 0.04 13.4 0.3 0.34 10.3 0.2 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 GAM24857.1 - 0.062 11.9 1.0 3.5 6.2 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.9 GAM24857.1 - 0.068 12.9 0.0 0.083 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 GAM24857.1 - 0.11 12.0 0.2 1.3 8.5 0.0 2.2 2 1 1 3 3 3 0 AAA domain Glyco_transf_49 PF13896.1 GAM24858.1 - 2.2e-44 151.8 2.8 3.4e-36 124.9 0.5 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM24858.1 - 6.5e-06 25.4 0.1 6.5e-06 25.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM24858.1 - 0.026 14.2 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 FNIP PF05725.7 GAM24859.1 - 2.6e-18 65.6 12.0 0.00013 21.8 0.0 6.7 8 0 0 8 8 8 5 FNIP Repeat TPR_11 PF13414.1 GAM24860.1 - 2.5e-52 174.4 33.7 1.9e-13 49.8 0.0 13.1 5 3 10 15 15 15 13 TPR repeat TPR_2 PF07719.12 GAM24860.1 - 2.5e-46 151.8 31.9 3.6e-06 26.4 0.0 18.1 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_1 PF00515.23 GAM24860.1 - 6.4e-43 142.6 31.8 1.2e-07 30.9 0.1 16.0 18 0 0 18 18 18 7 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24860.1 - 3.8e-40 136.0 15.4 3.1e-10 40.2 0.0 11.6 6 2 8 14 14 14 8 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24860.1 - 7.4e-38 128.3 34.9 3.2e-07 30.1 0.0 11.5 6 6 7 13 13 13 7 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24860.1 - 6.1e-35 116.5 9.5 9e-06 25.8 0.0 14.9 9 5 7 16 16 15 8 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24860.1 - 2.1e-34 117.4 17.3 1.3e-08 35.2 0.0 12.4 6 2 7 15 15 14 6 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24860.1 - 1.9e-33 111.8 21.5 0.0098 16.0 0.0 15.9 17 0 0 17 17 16 6 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24860.1 - 3.9e-28 94.9 11.8 0.0011 18.6 0.0 12.5 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24860.1 - 1.1e-26 90.5 24.4 6.2e-05 22.4 0.0 13.6 15 1 1 16 16 14 5 Tetratricopeptide repeat TPR_6 PF13174.1 GAM24860.1 - 8.4e-22 76.0 27.8 0.00034 20.8 0.0 13.3 16 0 0 16 16 14 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAM24860.1 - 4e-15 55.4 0.5 1.2e-07 31.5 0.0 6.1 6 1 1 7 7 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM24860.1 - 1.3e-14 54.0 30.8 0.0012 18.9 1.4 8.3 3 2 6 10 10 10 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 GAM24860.1 - 1.7e-13 50.0 16.6 0.092 12.7 0.1 10.7 12 0 0 12 12 11 4 Tetratricopeptide repeat PPR PF01535.15 GAM24860.1 - 0.00072 19.3 7.1 1.1 9.4 0.0 6.2 7 0 0 7 7 5 1 PPR repeat NARP1 PF12569.3 GAM24860.1 - 0.00081 18.2 0.6 0.00081 18.2 0.4 7.2 4 2 2 6 6 4 2 NMDA receptor-regulated protein 1 Rapsyn_N PF10579.4 GAM24860.1 - 0.0042 16.8 0.1 0.18 11.6 0.0 3.7 4 0 0 4 4 3 1 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.1 GAM24860.1 - 0.0057 16.5 20.4 0.23 11.3 0.9 7.2 9 0 0 9 9 9 2 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 GAM24860.1 - 2.2 8.1 10.6 1.7 8.5 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat MIP-T3 PF10243.4 GAM24860.1 - 8.2 4.7 52.8 12 4.1 36.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FNIP PF05725.7 GAM24861.1 - 6.1e-25 86.9 14.6 1.8e-07 31.0 0.0 6.8 4 3 5 9 9 9 6 FNIP Repeat LRR_7 PF13504.1 GAM24861.1 - 0.015 15.3 4.9 25 5.6 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat Sucrose_synth PF00862.14 GAM24861.1 - 0.039 11.9 0.0 0.056 11.4 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase FNIP PF05725.7 GAM24862.1 - 1.9e-19 69.3 16.4 3.5e-13 49.2 0.1 7.5 6 2 2 9 9 9 5 FNIP Repeat LRR_8 PF13855.1 GAM24862.1 - 3.1 7.6 11.3 17 5.2 3.7 4.4 3 2 1 4 4 4 0 Leucine rich repeat FNIP PF05725.7 GAM24863.1 - 8.8e-16 57.5 20.4 2.3e-10 40.2 0.0 7.4 6 2 2 9 9 9 5 FNIP Repeat FNIP PF05725.7 GAM24864.1 - 5e-19 67.9 7.9 7e-08 32.3 0.0 7.5 5 3 2 7 7 7 6 FNIP Repeat DrsE PF02635.10 GAM24865.1 - 9.1e-11 41.8 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family Cofilin_ADF PF00241.15 GAM24866.1 - 1.6e-14 53.8 0.8 2e-14 53.5 0.6 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FNIP PF05725.7 GAM24868.1 - 3.6e-21 74.8 10.2 5.2e-14 51.9 0.1 6.1 4 2 2 6 6 6 5 FNIP Repeat FNIP PF05725.7 GAM24869.1 - 1.4e-24 85.7 2.1 3.5e-09 36.4 0.0 6.8 4 2 5 9 9 9 6 FNIP Repeat Cyclin_N PF00134.18 GAM24869.1 - 0.11 12.0 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain FNIP PF05725.7 GAM24870.1 - 6.8e-23 80.3 5.6 8e-08 32.1 0.3 6.2 4 1 1 6 6 6 4 FNIP Repeat FNIP PF05725.7 GAM24872.1 - 2.8e-12 46.3 12.6 4.1e-06 26.6 1.8 6.4 5 2 1 6 6 6 3 FNIP Repeat LRR_4 PF12799.2 GAM24872.1 - 0.0019 17.7 1.0 5.6 6.6 0.0 4.6 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) Pkinase PF00069.20 GAM24873.1 - 2.8e-61 206.9 5.0 3.8e-61 206.5 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24873.1 - 4.3e-28 98.1 0.4 1.2e-20 73.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 GAM24873.1 - 3.8e-06 27.3 0.1 9.5e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM24873.1 - 0.0003 19.8 0.3 0.0034 16.3 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 GAM24873.1 - 0.0008 19.2 0.6 0.045 13.4 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM24873.1 - 0.0098 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Noggin PF05806.7 GAM24873.1 - 0.59 9.3 3.4 2.2 7.4 1.6 2.0 2 0 0 2 2 2 0 Noggin RhoGEF PF00621.15 GAM24874.1 - 4.8e-48 163.4 10.2 5.3e-48 163.2 5.5 2.3 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM24874.1 - 1.2e-22 80.0 9.5 1.3e-12 47.7 0.1 4.1 4 1 0 4 4 4 3 PH domain ArfGap PF01412.13 GAM24874.1 - 2.2e-19 69.3 0.1 2.2e-19 69.3 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CH PF00307.26 GAM24874.1 - 1.1e-15 57.6 1.0 5.4e-15 55.3 0.0 2.8 3 0 0 3 3 3 1 Calponin homology (CH) domain PH_11 PF15413.1 GAM24874.1 - 0.00016 21.9 13.9 0.0037 17.4 0.9 5.0 4 2 0 4 4 4 2 Pleckstrin homology domain CAMSAP_CH PF11971.3 GAM24874.1 - 0.00025 20.6 0.0 0.001 18.7 0.0 2.2 1 0 0 1 1 1 1 CAMSAP CH domain PH_8 PF15409.1 GAM24874.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.1 GAM24874.1 - 0.39 10.7 0.0 0.39 10.7 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain IQ PF00612.22 GAM24874.1 - 1.9 8.3 7.2 1 9.1 1.5 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif G8 PF10162.4 GAM24875.1 - 2.8e-23 82.0 1.2 7e-23 80.7 0.8 1.7 1 0 0 1 1 1 1 G8 domain G8 PF10162.4 GAM24877.1 - 1.2e-23 83.2 0.8 2.6e-23 82.1 0.6 1.6 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.1 GAM24877.1 - 0.06 11.8 0.1 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Amnionless Glyoxalase PF00903.20 GAM24878.1 - 6.1e-22 77.9 2.8 5e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM24878.1 - 3.5e-10 40.4 0.0 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 GAM24878.1 - 7.8e-10 38.7 0.3 0.00077 19.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 GAM24878.1 - 1.2e-06 28.4 0.0 3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 GAM24878.1 - 6.5e-06 26.1 0.2 0.013 15.3 0.1 3.3 2 1 0 2 2 2 2 Glyoxalase-like domain FNIP PF05725.7 GAM24879.1 - 7.3e-19 67.4 7.4 2.4e-08 33.8 0.0 6.7 4 3 3 7 7 7 6 FNIP Repeat Ank_3 PF13606.1 GAM24884.1 - 0.43 10.9 4.1 26 5.4 0.0 4.7 5 0 0 5 5 5 0 Ankyrin repeat HATPase_c_3 PF13589.1 GAM24886.1 - 3.7e-07 29.8 5.1 0.0013 18.4 0.2 4.1 3 1 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Actin PF00022.14 GAM24890.1 - 5.3e-10 38.2 0.0 6.6e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Actin IFP_35_N PF07334.8 GAM24890.1 - 0.28 11.1 0.9 0.46 10.4 0.6 1.3 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4208 PF13907.1 GAM24891.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Uma2 PF05685.7 GAM24893.1 - 1.2e-06 27.9 0.0 3.1e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Putative restriction endonuclease DP PF08781.5 GAM24893.1 - 0.041 13.5 0.2 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 Transcription factor DP HATPase_c_3 PF13589.1 GAM24895.1 - 0.0036 16.9 0.6 0.026 14.1 0.4 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chal_sti_synt_N PF00195.14 GAM24897.1 - 1e-31 109.9 0.5 2.2e-31 108.8 0.4 1.6 1 1 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 GAM24897.1 - 1.4e-10 41.2 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 GAM24897.1 - 1e-09 37.8 0.0 1.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 GAM24897.1 - 4e-05 23.5 0.0 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 GAM24897.1 - 0.00012 21.7 1.0 0.00036 20.1 0.4 2.0 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Annexin PF00191.15 GAM24897.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Annexin HATPase_c_3 PF13589.1 GAM24898.1 - 0.0041 16.7 3.4 0.12 12.0 0.2 3.3 3 1 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C39 PF03412.10 GAM24899.1 - 0.0021 17.8 0.3 0.013 15.2 0.2 2.1 1 1 0 1 1 1 1 Peptidase C39 family Fn3_assoc PF13287.1 GAM24899.1 - 0.025 14.6 3.3 0.058 13.4 0.3 2.6 2 0 0 2 2 2 0 Fn3 associated CHB_HEX_C_1 PF13290.1 GAM24899.1 - 0.25 11.1 5.8 0.42 10.4 2.5 2.6 2 1 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 GAM24899.1 - 0.51 10.2 5.9 1.2 9.0 2.6 2.6 2 1 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain TPR_11 PF13414.1 GAM24900.1 - 4e-12 45.6 0.1 1.2e-11 44.1 0.1 1.8 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 GAM24900.1 - 4.4e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_1 PF00515.23 GAM24900.1 - 2e-06 27.1 0.5 0.023 14.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24900.1 - 3.5e-06 26.8 0.4 0.0022 17.8 0.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM24900.1 - 1.1e-05 24.9 0.3 0.015 15.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24900.1 - 0.00019 21.9 0.0 0.00051 20.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24900.1 - 0.0011 18.6 0.1 1 9.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM24900.1 - 0.006 16.8 0.1 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM24900.1 - 0.0063 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM24900.1 - 0.034 13.9 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24900.1 - 0.045 14.3 0.1 2.1 9.2 0.0 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24900.1 - 0.37 11.1 3.1 0.49 10.7 0.1 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat NOA36 PF06524.7 GAM24900.1 - 7.4 5.7 18.6 12 5.0 12.9 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_11 PF13414.1 GAM24901.1 - 6.2e-11 41.7 0.0 1.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 GAM24901.1 - 8.3e-11 41.5 0.1 2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 GAM24901.1 - 1.1e-06 28.0 0.1 0.0001 21.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM24901.1 - 4.3e-06 26.0 0.7 0.0011 18.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24901.1 - 0.00012 21.6 0.1 0.45 10.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24901.1 - 0.013 15.4 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM24901.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24901.1 - 0.067 13.8 0.0 0.45 11.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM24901.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 GAM24901.1 - 0.17 12.5 0.0 0.49 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4470 PF14737.1 GAM24902.1 - 1.4e-11 43.9 0.1 3.4e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 GAM24902.1 - 2.2e-11 43.2 0.1 5.8e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 GAM24902.1 - 1.4e-06 27.7 1.0 1.4e-05 24.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM24902.1 - 8.1e-06 25.2 1.8 8.2e-05 22.0 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM24902.1 - 0.0004 20.2 0.0 0.0021 17.9 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM24902.1 - 0.0013 19.1 0.0 0.0096 16.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM24902.1 - 0.002 17.7 0.1 0.45 10.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM24902.1 - 0.0032 18.1 0.0 0.009 16.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM24902.1 - 0.0085 15.8 0.3 1.2 9.1 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM24902.1 - 0.01 15.6 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM24902.1 - 0.019 15.1 0.1 2 8.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SnoaL_2 PF12680.2 GAM24903.1 - 1.6e-05 25.2 0.0 1.8e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 GAM24903.1 - 0.0026 17.3 0.3 0.005 16.4 0.2 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 GAM24903.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3755 PF12579.3 GAM24903.1 - 0.048 13.0 0.2 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Adaptin_N PF01602.15 GAM24904.1 - 2.3e-137 458.5 24.5 3.6e-137 457.8 17.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 GAM24904.1 - 2.3e-14 53.4 3.8 2.1e-08 34.3 0.2 4.2 3 1 1 4 4 4 3 HEAT repeats AP3B1_C PF14796.1 GAM24904.1 - 3.8e-11 42.8 0.0 9.6e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.2 GAM24904.1 - 3.2e-10 40.1 18.5 1.6e-07 31.3 1.8 4.7 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM24904.1 - 1.1e-08 34.4 5.3 0.009 16.0 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 GAM24904.1 - 1.3e-05 25.5 4.6 0.054 13.9 0.0 5.5 6 1 1 7 7 7 2 HEAT-like repeat Cohesin_HEAT PF12765.2 GAM24904.1 - 0.019 14.9 4.1 0.64 10.0 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.7 GAM24904.1 - 6.1 6.0 22.0 0.44 9.7 11.2 1.9 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.20 GAM24905.1 - 1.1e-71 241.0 0.2 1.4e-71 240.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24905.1 - 4.1e-36 124.3 0.0 5.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24905.1 - 2.3e-09 36.6 0.0 3.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM24905.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM24905.1 - 0.0021 17.4 0.4 0.0039 16.5 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_C PF00433.19 GAM24905.1 - 0.0073 16.8 2.8 0.036 14.5 0.9 2.8 2 1 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 GAM24905.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ammonium_transp PF00909.16 GAM24906.1 - 6.6e-106 354.1 29.3 7.5e-106 353.9 20.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Adeno_E3_CR2 PF02439.10 GAM24906.1 - 1.5 8.4 6.9 8.3 6.0 1.0 3.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Aldose_epim PF01263.15 GAM24907.1 - 1.2e-49 169.0 0.1 1.5e-49 168.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF659 PF04937.10 GAM24907.1 - 0.076 12.4 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) YmaF PF12788.2 GAM24908.1 - 0.02 15.0 2.2 0.046 13.8 1.2 1.8 2 0 0 2 2 2 0 YmaF family SURF1 PF02104.10 GAM24909.1 - 8.5e-50 169.5 0.0 1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family cobW PF02492.14 GAM24910.1 - 4.1e-53 179.4 0.8 6.3e-53 178.8 0.5 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 GAM24910.1 - 7.5e-24 83.2 0.0 1.6e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 GAM24910.1 - 0.0047 16.6 1.8 0.0061 16.2 0.0 2.0 2 1 1 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 GAM24910.1 - 0.017 14.7 0.0 0.057 13.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 GAM24910.1 - 0.036 13.7 0.1 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 GAM24910.1 - 0.039 13.9 1.4 0.094 12.6 0.1 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM24910.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM24910.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 GAM24910.1 - 0.045 13.2 0.4 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 GAM24910.1 - 0.069 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 GAM24910.1 - 0.075 12.2 0.0 0.075 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM24910.1 - 0.12 12.6 1.9 0.22 11.8 0.1 2.1 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 GAM24910.1 - 0.61 10.3 0.0 0.61 10.3 0.0 3.1 3 1 0 3 3 2 0 AAA domain SH3_9 PF14604.1 GAM24911.1 - 7.9e-14 50.9 0.1 1.3e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM24911.1 - 2e-11 43.0 0.1 3.9e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM24911.1 - 9e-10 37.8 0.1 1.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DivIC PF04977.10 GAM24911.1 - 0.011 15.1 5.3 0.011 15.1 3.7 2.8 2 0 0 2 2 2 0 Septum formation initiator SLX9 PF15341.1 GAM24911.1 - 0.043 14.2 0.6 0.043 14.2 0.4 2.6 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 CDC45 PF02724.9 GAM24911.1 - 0.44 8.5 13.6 0.47 8.4 3.4 2.3 2 0 0 2 2 2 0 CDC45-like protein Med19 PF10278.4 GAM24911.1 - 0.84 9.2 17.0 0.075 12.7 2.5 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF3947 PF13135.1 GAM24911.1 - 1.1 9.5 3.7 0.24 11.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Sigma70_ner PF04546.8 GAM24911.1 - 1.2 8.7 22.3 0.043 13.4 6.2 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region ICMT PF04140.9 GAM24912.1 - 2.5e-28 98.0 0.0 4.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 GAM24912.1 - 9.5e-11 41.7 0.1 9.5e-11 41.7 0.1 2.7 2 2 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 GAM24912.1 - 0.0017 17.7 1.1 0.0017 17.7 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 GAM24912.1 - 0.0051 16.2 0.5 0.0098 15.2 0.1 1.6 1 1 0 1 1 1 1 NnrU protein Ribophorin_II PF05817.9 GAM24912.1 - 3.7 5.6 8.2 9.3 4.3 5.7 1.7 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Peptidase_C54 PF03416.14 GAM24913.1 - 1.8e-94 316.0 0.7 1.8e-94 316.0 0.5 2.1 2 0 0 2 2 2 1 Peptidase family C54 DUF2763 PF10961.3 GAM24914.1 - 0.059 13.7 0.5 0.061 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Na_Ca_ex PF01699.19 GAM24915.1 - 2.1e-20 72.7 25.5 1.2e-12 47.5 4.4 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 GAM24915.1 - 6.2e-14 52.1 11.3 6.2e-14 52.1 7.8 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF307) E1-E2_ATPase PF00122.15 GAM24915.1 - 1.2 8.1 4.4 1.3 8.0 0.1 2.6 2 0 0 2 2 2 0 E1-E2 ATPase E1-E2_ATPase PF00122.15 GAM24916.1 - 8.5e-20 70.7 1.7 1.1e-19 70.3 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM24916.1 - 7.8e-17 62.4 0.0 6.1e-16 59.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM24916.1 - 6e-13 49.3 0.1 2.1e-12 47.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM24916.1 - 2.4e-10 40.1 0.1 1.2e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM24916.1 - 6.6e-05 22.6 0.0 6.6e-05 22.6 0.0 3.5 4 1 0 4 4 4 1 haloacid dehalogenase-like hydrolase Vfa1 PF08432.5 GAM24916.1 - 1.1 9.2 15.8 0.035 14.1 4.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Hum_adeno_E3A PF05393.6 GAM24916.1 - 3.7 7.2 7.4 0.14 11.8 0.6 2.1 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Pkinase PF00069.20 GAM24917.1 - 6e-64 215.7 0.0 7.8e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM24917.1 - 6.8e-26 90.8 0.0 1.1e-25 90.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM24917.1 - 4.7e-07 29.0 0.0 7.8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM24917.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM24917.1 - 0.01 15.4 0.3 0.022 14.3 0.2 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 GAM24917.1 - 0.016 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 GAM24918.1 - 3.9e-43 147.1 3.2 4.9e-43 146.8 2.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family Sec8_exocyst PF04048.9 GAM24918.1 - 0.016 14.8 0.7 0.11 12.1 0.2 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain CH PF00307.26 GAM24920.1 - 1e-07 31.9 5.3 1.4e-07 31.5 0.0 3.8 3 0 0 3 3 3 1 Calponin homology (CH) domain GRAB PF10375.4 GAM24920.1 - 0.012 15.2 0.2 0.037 13.7 0.2 1.9 1 0 0 1 1 1 0 GRIP-related Arf-binding domain CBM49 PF09478.5 GAM24921.1 - 6.3e-14 51.8 4.4 1.4e-13 50.7 3.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 dCMP_cyt_deam_1 PF00383.17 GAM24921.1 - 2.6e-10 39.8 0.4 6.3e-10 38.6 0.3 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 GAM24921.1 - 0.098 12.5 0.5 0.39 10.5 0.1 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase BHD_3 PF10405.4 GAM24922.1 - 1.9e-22 78.7 0.1 3.7e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 GAM24922.1 - 1.8e-20 72.8 0.3 1.8e-20 72.8 0.2 4.2 3 1 1 4 4 4 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 GAM24922.1 - 2e-10 39.9 0.2 1.5e-08 34.0 0.1 3.2 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 GAM24922.1 - 2.8e-09 37.1 0.0 2.8e-09 37.1 0.0 3.8 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 TIG PF01833.19 GAM24925.1 - 3.7e-19 68.4 54.1 1.3e-05 25.0 5.7 7.0 7 0 0 7 7 7 5 IPT/TIG domain Lectin_C PF00059.16 GAM24925.1 - 2.1e-06 28.2 0.0 1e-05 26.1 0.0 2.3 1 0 0 1 1 1 1 Lectin C-type domain EGF_2 PF07974.8 GAM24925.1 - 0.013 15.6 8.8 0.036 14.2 6.1 1.8 1 0 0 1 1 1 0 EGF-like domain DnaJ_CXXCXGXG PF00684.14 GAM24926.1 - 0.00062 19.7 22.5 0.35 10.9 8.8 3.2 1 1 1 2 2 2 2 DnaJ central domain zf-rbx1 PF12678.2 GAM24926.1 - 0.6 10.2 9.0 4.5 7.4 6.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-CCHC PF00098.18 GAM24926.1 - 8.2 6.5 19.1 2.8 8.0 1.3 4.3 4 0 0 4 4 4 0 Zinc knuckle Ribosomal_L20 PF00453.13 GAM24927.1 - 2.6e-34 117.3 1.9 3.1e-34 117.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 LSM PF01423.17 GAM24928.1 - 1.3e-18 66.2 1.0 2e-18 65.6 0.7 1.2 1 0 0 1 1 1 1 LSM domain EIF_2_alpha PF07541.7 GAM24928.1 - 0.012 15.2 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit ATPgrasp_TupA PF14305.1 GAM24928.1 - 0.029 13.6 0.1 0.034 13.4 0.1 1.0 1 0 0 1 1 1 0 TupA-like ATPgrasp Rota_NSP4 PF01452.11 GAM24928.1 - 0.058 12.7 0.7 0.065 12.5 0.5 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein Adap_comp_sub PF00928.16 GAM24929.1 - 9.6e-55 185.4 0.0 1.2e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM24929.1 - 0.059 13.0 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Clathrin adaptor complex small chain TerD PF02342.13 GAM24930.1 - 1.3e-54 184.3 0.0 1.8e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 TerD domain Ras PF00071.17 GAM24931.1 - 9.6e-55 184.3 0.0 1.1e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24931.1 - 3.5e-22 79.1 0.0 4.6e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM24931.1 - 2e-17 62.9 0.1 2.2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM24931.1 - 3.2e-07 29.7 0.0 3.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM24931.1 - 1.9e-06 27.4 0.2 1.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM24931.1 - 4.3e-05 22.8 0.0 5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM24931.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 GAM24931.1 - 0.0082 15.7 0.1 0.013 15.0 0.0 1.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.15 GAM24931.1 - 0.0086 14.7 0.4 0.14 10.7 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 GAM24931.1 - 0.018 14.5 0.1 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation BUD22 PF09073.5 GAM24932.1 - 0.34 9.9 17.4 0.38 9.7 12.0 1.0 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 GAM24932.1 - 0.87 7.2 2.8 0.97 7.0 1.9 1.0 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 GAM24932.1 - 3.9 7.4 11.2 73 3.3 9.4 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4614 PF15391.1 GAM24933.1 - 3.1 7.5 19.8 3.3 7.4 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Pex14_N PF04695.8 GAM24933.1 - 4.8 7.2 8.5 5.3 7.0 5.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.8 GAM24933.1 - 5.1 7.5 24.3 6.6 7.2 16.8 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain NPR2 PF06218.6 GAM24933.1 - 8 5.0 7.2 9.1 4.8 5.0 1.0 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Pol_alpha_B_N PF08418.5 GAM24933.1 - 8.5 5.8 11.8 8.9 5.7 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Transketolase_N PF00456.16 GAM24934.1 - 5.3e-108 360.7 0.3 6.9e-108 360.3 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM24934.1 - 2.7e-43 147.4 0.0 1.5e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM24934.1 - 2.3e-13 50.1 0.0 2.2e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 GAM24934.1 - 5.7e-08 32.0 0.1 5.8e-06 25.4 0.0 2.7 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 GAM24934.1 - 0.00058 19.4 0.0 0.0043 16.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 GAM24934.1 - 0.0017 17.1 0.1 0.0028 16.4 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component UBA_3 PF09288.5 GAM24934.1 - 0.053 13.1 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3939 PF13075.1 GAM24934.1 - 0.13 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) PT PF04886.7 GAM24938.1 - 5.5e-22 76.7 53.4 0.0043 16.3 1.8 7.0 1 1 1 2 2 2 1 PT repeat DUF2454 PF10521.4 GAM24938.1 - 0.11 11.4 6.7 0.36 9.7 0.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2454) Yae1_N PF09811.4 GAM24939.1 - 8.3e-44 146.8 28.9 3.7e-07 29.5 0.8 8.8 1 1 6 7 7 7 7 Essential protein Yae1, N terminal DUF637 PF04830.8 GAM24939.1 - 2.8e-05 23.8 2.7 2.6 7.6 1.9 4.9 1 1 0 1 1 1 1 Possible hemagglutinin (DUF637) Dpy-30 PF05186.8 GAM24939.1 - 0.0052 16.2 23.0 2.1e+02 1.5 0.0 12.0 3 2 1 4 4 4 0 Dpy-30 motif DUF2597 PF10772.4 GAM24939.1 - 2.6 7.9 21.7 6.7e+02 0.1 3.0 8.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2597) ABC_tran PF00005.22 GAM24940.1 - 3.7e-41 140.6 0.0 1e-22 80.9 0.0 4.8 4 2 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 GAM24940.1 - 2.4e-17 62.5 5.4 2.4e-17 62.5 3.7 5.7 4 1 2 6 6 3 1 ABC transporter AAA_21 PF13304.1 GAM24940.1 - 6e-15 55.9 8.1 0.0003 20.8 0.1 5.2 4 1 0 5 5 5 4 AAA domain DUF258 PF03193.11 GAM24940.1 - 2.8e-07 29.8 0.0 0.0043 16.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 GAM24940.1 - 3.1e-07 30.5 0.3 0.07 13.2 0.1 3.7 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 GAM24940.1 - 7.1e-06 25.9 0.0 0.026 14.4 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM24940.1 - 1.6e-05 24.3 3.5 0.02 14.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain Miro PF08477.8 GAM24940.1 - 2e-05 25.0 5.0 0.2 12.1 0.0 4.2 4 0 0 4 4 3 2 Miro-like protein MobB PF03205.9 GAM24940.1 - 3.3e-05 23.5 0.5 0.2 11.3 0.1 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 GAM24940.1 - 4.7e-05 22.9 1.5 0.65 9.3 0.0 3.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 GAM24940.1 - 4.9e-05 23.4 0.3 0.32 11.1 0.0 3.7 4 0 0 4 4 3 2 RNA helicase AAA_33 PF13671.1 GAM24940.1 - 0.00012 21.9 0.0 0.4 10.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 GAM24940.1 - 0.00013 21.6 0.9 0.52 9.9 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 GAM24940.1 - 0.00034 21.4 0.0 0.011 16.5 0.0 6.0 5 1 0 5 5 4 2 AAA domain AAA PF00004.24 GAM24940.1 - 0.0004 20.6 0.8 0.21 11.7 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 GAM24940.1 - 0.0011 18.5 0.8 1.3 8.3 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain AAA_28 PF13521.1 GAM24940.1 - 0.0013 18.7 0.0 0.8 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM24940.1 - 0.0015 18.5 0.2 0.7 9.8 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 GAM24940.1 - 0.0018 17.7 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAM24940.1 - 0.0046 16.8 0.0 0.73 9.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM24940.1 - 0.053 13.2 0.5 5.6 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 GAM24940.1 - 0.49 10.6 0.0 0.49 10.6 0.0 6.9 5 1 0 5 5 4 0 AAA domain B12D PF06522.6 GAM24941.1 - 2.3e-07 30.4 0.0 2.4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit EPL1 PF10513.4 GAM24942.1 - 4.3e-21 75.8 0.3 4.3e-21 75.8 0.2 5.1 3 2 0 3 3 3 1 Enhancer of polycomb-like DUF4477 PF14780.1 GAM24942.1 - 0.12 11.7 2.4 0.26 10.6 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) DUF106 PF01956.11 GAM24942.1 - 6.5 6.2 10.1 0.28 10.6 2.0 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 RIC1 PF07064.8 GAM24943.1 - 1.9e-69 234.0 0.0 3.3e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 GAM24943.1 - 3.3 7.7 9.7 0.35 10.8 0.5 3.6 5 0 0 5 5 5 0 WD domain, G-beta repeat GATA PF00320.22 GAM24944.1 - 2.7e-13 48.9 5.9 4.3e-13 48.3 4.1 1.3 1 0 0 1 1 1 1 GATA zinc finger Calpain_III PF01067.17 GAM24945.1 - 1.7e-46 157.4 0.2 2e-17 63.1 0.0 3.4 3 0 0 3 3 3 3 Calpain large subunit, domain III DoxA PF07680.6 GAM24945.1 - 0.14 11.7 0.1 1.1 8.8 0.0 2.3 1 1 0 2 2 2 0 TQO small subunit DoxA DUF1296 PF06972.6 GAM24946.1 - 0.0009 19.1 0.4 0.0018 18.2 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1296) HBS1_N PF08938.5 GAM24946.1 - 0.0059 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 HBS1 N-terminus CUE PF02845.11 GAM24946.1 - 0.049 13.1 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 CUE domain SIR2_2 PF13289.1 GAM24948.1 - 1.5e-27 96.1 0.1 3.8e-27 94.9 0.1 1.7 1 0 0 1 1 1 1 SIR2-like domain RhoGAP PF00620.22 GAM24949.1 - 4.1e-34 117.3 0.3 8.4e-34 116.3 0.2 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 GAM24949.1 - 2.3e-24 85.5 4.2 2.1e-18 66.4 0.1 3.2 3 0 0 3 3 3 2 PH domain PH_11 PF15413.1 GAM24949.1 - 1.3e-08 35.0 3.6 2.6e-05 24.4 0.1 3.9 3 1 0 3 3 3 2 Pleckstrin homology domain F-box-like PF12937.2 GAM24949.1 - 1.5e-07 30.9 3.9 2.4e-07 30.3 1.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM24949.1 - 8.2e-07 28.5 2.1 2.9e-06 26.7 1.4 2.1 1 0 0 1 1 1 1 F-box domain PH_8 PF15409.1 GAM24949.1 - 5.8e-06 26.2 3.1 0.034 14.2 0.0 3.2 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 GAM24949.1 - 0.00088 19.1 0.7 0.012 15.5 0.0 2.8 3 0 0 3 3 3 1 PH domain Ras PF00071.17 GAM24950.1 - 9.4e-60 200.6 0.1 1.1e-59 200.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24950.1 - 1.3e-19 70.8 0.0 2.4e-19 70.0 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM24950.1 - 5.1e-13 48.6 0.0 6.7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM24950.1 - 6.5e-07 29.3 0.1 9.5e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM24950.1 - 4.6e-05 22.9 0.0 0.00093 18.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM24950.1 - 0.0002 20.5 0.0 0.00035 19.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM24950.1 - 0.0066 15.6 0.0 0.018 14.3 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAM24950.1 - 0.016 15.3 0.0 0.04 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAM24950.1 - 0.023 14.2 0.0 0.056 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 GAM24950.1 - 0.069 12.1 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain MIF4G PF02854.14 GAM24951.1 - 3.5e-07 29.8 0.4 3.5e-07 29.8 0.2 2.6 2 1 0 2 2 2 1 MIF4G domain TMF_TATA_bd PF12325.3 GAM24952.1 - 0.0052 16.4 0.3 0.0052 16.4 0.2 2.6 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding BAR PF03114.13 GAM24952.1 - 0.022 14.2 4.0 0.028 13.9 2.8 1.2 1 0 0 1 1 1 0 BAR domain DUF3508 PF12018.3 GAM24952.1 - 0.12 11.3 3.7 4.5 6.1 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3508) Striatin PF08232.7 GAM24952.1 - 0.34 11.2 5.9 0.1 12.8 1.4 1.9 2 0 0 2 2 2 0 Striatin family E1-E2_ATPase PF00122.15 GAM24953.1 - 1.9e-19 69.6 0.0 1.9e-19 69.6 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM24953.1 - 1.4e-14 55.0 1.7 3e-10 40.8 0.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM24953.1 - 6.9e-14 52.4 0.0 3.6e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM24953.1 - 1.9e-10 40.5 0.0 8.4e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM24953.1 - 0.0023 17.5 0.1 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FtsL PF04999.8 GAM24953.1 - 0.21 11.3 2.6 0.26 11.0 0.1 2.5 2 0 0 2 2 2 0 Cell division protein FtsL Adaptin_N PF01602.15 GAM24954.1 - 2.8e-82 276.7 0.6 2.8e-82 276.7 0.4 1.5 2 0 0 2 2 2 1 Adaptin N terminal region B2-adapt-app_C PF09066.5 GAM24954.1 - 1.9e-11 43.8 0.1 8.7e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 GAM24954.1 - 2.1e-07 31.1 0.0 0.002 18.3 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 GAM24954.1 - 6.9e-06 25.7 0.2 1.9 8.8 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat DUF2435 PF10363.4 GAM24954.1 - 0.00052 19.8 0.2 0.034 14.0 0.0 4.0 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 GAM24954.1 - 0.001 18.9 4.8 0.0087 15.9 0.0 4.1 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 ATP_bind_4 PF01902.12 GAM24955.1 - 1.6e-23 83.2 0.0 8.7e-23 80.8 0.0 1.8 1 1 0 1 1 1 1 ATP-binding region QueC PF06508.8 GAM24955.1 - 0.14 11.4 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC WD40 PF00400.27 GAM24956.1 - 8.3e-124 399.5 79.4 7e-12 44.7 0.2 20.6 21 0 0 21 21 21 17 WD domain, G-beta repeat TROVE PF05731.6 GAM24956.1 - 3.4e-62 210.4 0.2 2.5e-61 207.5 0.1 2.2 1 1 0 1 1 1 1 TROVE domain eIF2A PF08662.6 GAM24956.1 - 6.1e-16 58.6 17.1 0.0076 15.9 0.2 8.1 3 3 5 8 8 8 6 Eukaryotic translation initiation factor eIF2A DUF4062 PF13271.1 GAM24956.1 - 3.4e-09 36.6 0.0 3.3e-07 30.2 0.0 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4062) NACHT PF05729.7 GAM24956.1 - 4.8e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 GAM24956.1 - 2e-06 27.3 0.4 0.52 10.0 0.0 6.9 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 GAM24956.1 - 6.4e-06 26.3 0.1 3.9e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 GAM24956.1 - 5.9e-05 23.1 0.1 0.00082 19.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 GAM24956.1 - 0.00034 20.3 1.3 0.00051 19.8 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 GAM24956.1 - 0.0062 17.0 0.0 0.092 13.2 0.0 3.2 2 0 0 2 2 1 1 Miro-like protein Zeta_toxin PF06414.7 GAM24956.1 - 0.087 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Gly-rich_Ago1 PF12764.2 GAM24956.1 - 0.39 11.3 5.2 1.6 9.4 3.6 2.0 1 0 0 1 1 1 0 Glycine-rich region of argonaut ABC2_membrane_2 PF12679.2 GAM24957.1 - 0.021 13.7 7.5 0.029 13.2 5.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Shisa PF13908.1 GAM24957.1 - 6.6 6.8 7.3 12 5.9 5.1 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DEAD PF00270.24 GAM24959.1 - 4.8e-45 153.0 0.0 2.9e-42 144.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM24959.1 - 4.9e-21 74.3 0.4 1.6e-20 72.7 0.3 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM24959.1 - 0.00013 21.8 0.0 0.00045 20.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAM24959.1 - 0.0076 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.9 GAM24959.1 - 0.049 12.9 0.0 3.6 6.8 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain DUF1253 PF06862.7 GAM24959.1 - 0.052 11.9 0.0 2.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Methyltransf_11 PF08241.7 GAM24960.1 - 2e-13 50.6 0.1 3.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM24960.1 - 5.3e-10 39.0 0.0 6.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM24960.1 - 1.1e-08 34.4 0.6 2.3e-07 30.2 0.4 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM24960.1 - 1.2e-07 32.3 0.0 1.6e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM24960.1 - 2.8e-06 27.6 0.1 5.3e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM24960.1 - 4.1e-05 23.9 0.0 7.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAM24960.1 - 6.8e-05 22.3 0.0 0.00012 21.5 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.1 GAM24960.1 - 0.00028 20.6 0.0 0.00042 20.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 GAM24960.1 - 0.0005 19.5 0.0 0.00072 19.0 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Alpha_L_fucos PF01120.12 GAM24961.1 - 2.1e-108 362.2 3.2 2.7e-108 361.9 2.2 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase Kelch_3 PF13415.1 GAM24962.1 - 3.8e-54 179.7 9.4 4.5e-10 39.4 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM24962.1 - 5.4e-53 176.5 14.2 1.3e-09 37.6 0.1 6.2 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM24962.1 - 1e-47 159.4 7.9 4.6e-08 32.4 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM24962.1 - 4.4e-42 140.3 12.1 4.3e-09 35.7 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM24962.1 - 1.2e-40 135.9 14.3 4.6e-10 39.2 0.0 6.2 2 1 4 6 6 6 6 Kelch motif Kelch_5 PF13854.1 GAM24962.1 - 4.6e-39 131.7 5.4 2.2e-08 33.8 0.1 6.2 6 0 0 6 6 6 5 Kelch motif PQQ_3 PF13570.1 GAM24962.1 - 2.5e-05 24.3 5.8 0.11 12.7 0.0 6.0 6 1 0 6 6 6 1 PQQ-like domain DUF1668 PF07893.8 GAM24962.1 - 0.035 13.2 3.0 3.4 6.6 0.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1668) CLN5 PF15014.1 GAM24963.1 - 2.5e-33 115.7 12.2 3.8e-33 115.1 8.5 1.3 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 DUF1647 PF07801.6 GAM24963.1 - 0.053 13.0 1.6 0.085 12.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Abhydrolase_6 PF12697.2 GAM24964.1 - 7.1e-19 68.5 0.0 1.1e-18 68.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM24964.1 - 1.5e-14 54.1 0.5 5e-14 52.4 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM24964.1 - 4e-11 42.8 0.0 1.9e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM24964.1 - 3.4e-08 33.3 1.1 1.4e-07 31.3 0.1 2.3 3 0 0 3 3 3 1 PGAP1-like protein DUF2048 PF09752.4 GAM24964.1 - 2.2e-05 23.5 0.0 3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 GAM24964.1 - 0.00099 18.7 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 GAM24964.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 GAM24964.1 - 0.0028 16.1 0.0 0.0042 15.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 GAM24964.1 - 0.016 14.9 0.4 0.042 13.5 0.3 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 GAM24964.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 GAM24964.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.15 GAM24964.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF2305 PF10230.4 GAM24964.1 - 0.023 14.1 0.1 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 GAM24964.1 - 0.076 12.2 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family PQ-loop PF04193.9 GAM24966.1 - 6.8e-14 51.1 16.1 1.7e-10 40.3 4.0 4.3 4 1 1 5 5 5 2 PQ loop repeat MtN3_slv PF03083.11 GAM24966.1 - 7.7 6.4 15.1 12 5.8 0.8 2.9 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Methyltransf_31 PF13847.1 GAM24967.1 - 2e-17 63.2 0.0 2.4e-17 62.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM24967.1 - 4.1e-15 56.3 0.0 6.6e-15 55.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM24967.1 - 3.4e-14 52.8 0.0 4.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM24967.1 - 3.3e-13 49.3 0.0 7.3e-13 48.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 GAM24967.1 - 2.1e-06 27.4 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 GAM24967.1 - 2.8e-06 27.6 0.0 4.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM24967.1 - 9.3e-06 25.1 0.0 2.4e-05 23.8 0.0 1.5 1 1 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 GAM24967.1 - 1.2e-05 25.6 0.0 4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM24967.1 - 2.7e-05 23.9 0.0 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 GAM24967.1 - 5e-05 22.5 0.0 0.00012 21.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 GAM24967.1 - 6.8e-05 22.3 0.0 9.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 GAM24967.1 - 0.00024 21.5 0.0 0.00045 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 GAM24967.1 - 0.001 18.1 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_3 PF01596.12 GAM24967.1 - 0.0021 17.1 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 GAM24967.1 - 0.0078 15.8 0.0 0.011 15.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 GAM24967.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TehB PF03848.9 GAM24967.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.7 GAM24967.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 GAM24967.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_10 PF05971.7 GAM24967.1 - 0.03 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF890) DOT1 PF08123.8 GAM24967.1 - 0.039 13.2 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Ubie_methyltran PF01209.13 GAM24967.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Eco57I PF07669.6 GAM24967.1 - 0.1 12.9 0.1 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase PCMT PF01135.14 GAM24967.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4164 PF13747.1 GAM24968.1 - 0.0079 16.3 7.8 0.01 15.9 1.5 3.3 2 1 2 4 4 4 1 Domain of unknown function (DUF4164) Phage_cap_E PF03864.10 GAM24968.1 - 0.042 12.7 2.1 0.13 11.1 0.5 2.1 2 0 0 2 2 2 0 Phage major capsid protein E TMCO5 PF14992.1 GAM24968.1 - 0.046 12.8 16.6 0.064 12.3 11.5 1.3 1 0 0 1 1 1 0 TMCO5 family Nsp1_C PF05064.8 GAM24968.1 - 0.075 12.6 3.2 0.22 11.1 0.2 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region IFT57 PF10498.4 GAM24968.1 - 0.4 9.3 15.8 0.3 9.7 9.6 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FliD_C PF07195.7 GAM24968.1 - 0.62 9.3 7.1 1.7 7.9 0.7 2.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus IncA PF04156.9 GAM24968.1 - 1.9 8.0 15.2 1.5 8.4 3.4 2.2 1 1 1 2 2 2 0 IncA protein DUF1284 PF06935.6 GAM24968.1 - 2.5 8.3 10.8 2.5 8.3 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1284) MDH PF02315.11 GAM24968.1 - 3.5 7.6 8.3 1.5 8.7 0.6 2.6 2 1 0 2 2 2 0 Methanol dehydrogenase beta subunit Exonuc_VII_L PF02601.10 GAM24968.1 - 5.1 6.2 13.7 8.4 5.4 9.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF922 PF06037.6 GAM24968.1 - 7.1 5.9 15.2 0.12 11.7 3.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF922) Lactamase_B_2 PF12706.2 GAM24970.1 - 3.5e-32 111.5 0.4 5.2e-32 110.9 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM24970.1 - 1.1e-14 54.4 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM24970.1 - 0.35 10.4 2.3 1.1 8.8 1.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Rep_fac_C PF08542.6 GAM24971.1 - 2.1e-22 78.8 0.0 1.5e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAM24971.1 - 3.2e-13 49.6 0.0 7.7e-11 41.9 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 GAM24971.1 - 5e-13 49.3 0.0 1.1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAM24971.1 - 5.1e-09 35.3 0.0 5.1e-06 25.4 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 GAM24971.1 - 6.2e-08 32.6 0.0 1.7e-07 31.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 GAM24971.1 - 5.7e-07 29.7 0.1 0.0055 16.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM24971.1 - 1.2e-06 28.6 0.0 6.5e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 GAM24971.1 - 4e-06 26.4 0.0 1.3e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 GAM24971.1 - 7.9e-06 25.5 0.0 0.0077 15.6 0.0 2.4 1 1 1 2 2 2 2 AAA-like domain AAA_18 PF13238.1 GAM24971.1 - 7.1e-05 23.1 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 GAM24971.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 GAM24971.1 - 0.00028 20.5 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAM24971.1 - 0.00052 19.5 0.0 0.056 12.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 GAM24971.1 - 0.00054 19.7 0.0 0.066 12.9 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.9 GAM24971.1 - 0.00063 19.4 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 GAM24971.1 - 0.00095 18.2 0.0 0.0022 17.0 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 GAM24971.1 - 0.0012 17.9 0.0 0.01 14.9 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 GAM24971.1 - 0.004 16.7 0.1 0.037 13.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM24971.1 - 0.004 16.5 0.0 0.0086 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM24971.1 - 0.0049 16.8 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 GAM24971.1 - 0.0051 16.2 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 GAM24971.1 - 0.0075 17.0 0.4 0.017 15.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM24971.1 - 0.0082 16.2 0.0 0.063 13.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 GAM24971.1 - 0.0093 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 GAM24971.1 - 0.017 14.0 0.2 0.11 11.4 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 GAM24971.1 - 0.02 15.1 0.0 0.064 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAM24971.1 - 0.023 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM24971.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 GAM24971.1 - 0.041 12.7 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 GAM24971.1 - 0.055 13.3 0.1 0.16 11.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 GAM24971.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_29 PF13555.1 GAM24971.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 GAM24971.1 - 0.063 12.9 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAM24971.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 GAM24971.1 - 0.086 12.0 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 GAM24971.1 - 0.1 12.8 0.0 0.32 11.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.11 GAM24971.1 - 0.12 11.6 0.0 7 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF3215 PF11503.3 GAM24972.1 - 0.0084 15.7 0.0 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3215) Closter_coat PF01785.12 GAM24972.1 - 0.027 13.5 0.5 0.028 13.4 0.4 1.0 1 0 0 1 1 1 0 Closterovirus coat protein LAGLIDADG_3 PF14528.1 GAM24972.1 - 0.059 13.6 0.1 0.067 13.4 0.1 1.2 1 0 0 1 1 1 0 LAGLIDADG-like domain Nramp PF01566.13 GAM24973.1 - 1.8e-136 454.6 23.5 1.8e-136 454.6 16.3 2.0 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF3810 PF12725.2 GAM24973.1 - 6.1 5.6 6.3 16 4.3 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FNIP PF05725.7 GAM24974.1 - 1.4e-44 149.8 27.4 1.1e-17 63.7 0.4 6.1 4 2 3 7 7 7 5 FNIP Repeat DUF1769 PF08588.5 GAM24974.1 - 6.4e-05 22.8 1.2 1.1 9.2 0.0 4.0 2 1 2 4 4 4 3 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM24975.1 - 2.4e-74 245.0 32.0 1.8e-14 53.4 0.0 9.0 7 2 1 9 9 9 8 FNIP Repeat LRR_5 PF13306.1 GAM24975.1 - 2.4e-08 33.7 1.0 0.00042 20.0 0.0 3.9 1 1 0 3 3 3 2 Leucine rich repeats (6 copies) LRR_4 PF12799.2 GAM24975.1 - 0.037 13.6 1.0 0.037 13.6 0.7 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) RNA_pol_Rpb1_5 PF04998.12 GAM24976.1 - 6.7e-97 324.0 0.9 1e-96 323.4 0.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 GAM24976.1 - 2.8e-94 316.1 1.6 4.3e-94 315.5 1.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 GAM24976.1 - 7.2e-70 234.2 0.0 2e-69 232.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 GAM24976.1 - 1.1e-36 125.9 0.0 3.2e-35 121.1 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 GAM24976.1 - 8.3e-33 112.3 0.0 7.2e-32 109.3 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Rifin_STEVOR PF02009.11 GAM24978.1 - 2.9 7.4 4.9 4.1 6.9 3.4 1.2 1 0 0 1 1 1 0 Rifin/stevor family Response_reg PF00072.19 GAM24979.1 - 1.8e-21 76.2 0.1 3.3e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 GAM24980.1 - 8e-30 102.8 0.1 1.5e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM24980.1 - 3.3e-16 59.0 0.0 7.2e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 GAM24980.1 - 5.5e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.1 GAM24980.1 - 0.00018 21.8 0.0 0.00074 19.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.1 GAM24980.1 - 0.064 12.9 0.1 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CRAL_TRIO_2 PF13716.1 GAM24981.1 - 3.6e-41 140.5 0.5 6e-41 139.8 0.3 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 GAM24981.1 - 5.6e-07 29.1 1.4 7.9e-07 28.7 0.4 1.8 1 1 1 2 2 2 1 CRAL/TRIO domain DSPc PF00782.15 GAM24982.1 - 2.9e-32 111.0 0.1 2.9e-32 111.0 0.1 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM24982.1 - 0.0001 21.7 0.0 0.0001 21.7 0.0 1.8 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Rad52_Rad22 PF04098.10 GAM24984.1 - 1.9e-44 151.1 0.0 3.1e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RNase_PH PF01138.16 GAM24985.1 - 8.2e-25 87.6 0.7 2.1e-24 86.3 0.3 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Met_10 PF02475.11 GAM24985.1 - 0.021 14.3 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein RNase_PH_C PF03725.10 GAM24985.1 - 0.028 14.3 0.1 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Lip_A_acyltrans PF03279.8 GAM24985.1 - 0.16 10.8 0.0 1.5 7.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase Ras PF00071.17 GAM24986.1 - 2.1e-44 150.7 0.1 2.5e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM24986.1 - 5e-19 68.9 0.0 9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM24986.1 - 2.6e-09 36.5 0.1 3.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM24986.1 - 7.1e-07 28.6 0.0 8.2e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM24986.1 - 0.00012 21.6 0.3 0.0071 15.7 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 GAM24986.1 - 0.0015 18.0 0.0 0.0077 15.7 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 GAM24986.1 - 0.0067 16.1 0.3 0.017 14.8 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 GAM24986.1 - 0.0074 15.5 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 GAM24986.1 - 0.011 15.3 0.0 0.28 10.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 GAM24986.1 - 0.024 14.5 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 GAM24986.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 GAM24986.1 - 0.05 13.1 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAM24986.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM24986.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 GAM24986.1 - 0.14 11.1 0.1 2.3 7.1 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_32 PF13654.1 GAM24986.1 - 0.18 10.4 0.1 0.28 9.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 GAM24987.1 - 2.9e-30 104.5 0.5 4.6e-29 100.6 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme LRR_1 PF00560.28 GAM24987.1 - 3.8e-05 23.1 22.0 3.6 7.9 0.2 11.2 11 0 0 11 11 11 2 Leucine Rich Repeat LRR_7 PF13504.1 GAM24987.1 - 0.0024 17.7 24.8 9.8 6.8 0.1 10.0 10 0 0 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 GAM24987.1 - 0.0042 17.0 26.3 1.7 8.9 0.0 10.9 12 0 0 12 12 12 2 Leucine Rich repeat zf-CCCH PF00642.19 GAM24987.1 - 0.0066 16.0 2.7 0.024 14.3 1.8 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CLU PF13236.1 GAM24988.1 - 1.9e-54 184.4 0.0 3.9e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM24988.1 - 2.7e-15 56.7 0.1 2.7e-15 56.7 0.1 2.6 4 1 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 CLASP_N PF12348.3 GAM24989.1 - 1.4e-23 83.4 20.6 2.8e-08 33.4 0.6 6.2 6 1 0 6 6 6 4 CLASP N terminal HEAT PF02985.17 GAM24989.1 - 3.4e-15 54.6 8.0 0.57 10.4 0.0 10.5 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 GAM24989.1 - 4.8e-13 49.1 8.6 0.037 14.2 0.1 9.4 7 2 2 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 GAM24989.1 - 1e-06 29.0 9.2 0.6 10.6 0.0 7.4 8 0 0 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 GAM24989.1 - 6.4e-06 26.4 0.3 2.5 8.5 0.0 7.1 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region PARP PF00644.15 GAM24990.1 - 7.6e-29 100.6 0.8 3.9e-28 98.2 0.5 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain VIT PF08487.5 GAM24990.1 - 1.2e-27 95.9 0.0 3.9e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 GAM24990.1 - 1.3e-25 89.9 0.1 6.7e-25 87.5 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain 14-3-3 PF00244.15 GAM24990.1 - 2.3e-20 72.7 4.2 2.3e-20 72.7 2.9 2.4 3 0 0 3 3 3 1 14-3-3 protein VWA PF00092.23 GAM24990.1 - 1.8e-14 53.8 0.0 6.4e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAM24990.1 - 1.4e-10 40.4 0.0 3.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain I_LWEQ PF01608.12 GAM24990.1 - 6.5e-06 26.1 2.3 3e-05 24.0 1.6 2.1 1 0 0 1 1 1 1 I/LWEQ domain BRCT PF00533.21 GAM24990.1 - 9.9e-06 25.6 0.0 3.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TPR_12 PF13424.1 GAM24990.1 - 0.00045 20.1 2.9 0.02 14.8 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Ribosomal_60s PF00428.14 GAM24990.1 - 0.002 18.4 6.1 0.0033 17.7 3.6 5.9 6 1 0 6 6 5 2 60s Acidic ribosomal protein vWA-TerF-like PF10138.4 GAM24990.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Thg1 PF04446.7 GAM24991.1 - 7e-39 132.5 0.1 1.1e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 GAM24991.1 - 6.1e-17 61.4 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain GTP_EFTU_D3 PF03143.12 GAM24991.1 - 0.055 13.6 0.1 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain Acetyltransf_3 PF13302.1 GAM24992.1 - 2.9e-17 63.1 0.0 4.6e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM24992.1 - 2e-05 24.4 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM24992.1 - 0.0037 17.2 0.0 0.0089 15.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Myotub-related PF06602.9 GAM24993.1 - 9.3e-91 304.2 10.8 1e-61 208.6 0.6 3.2 3 0 0 3 3 3 2 Myotubularin-like phosphatase domain GRAM PF02893.15 GAM24993.1 - 0.00066 19.1 0.0 0.0021 17.5 0.0 1.8 2 0 0 2 2 2 1 GRAM domain Glyco_transf_20 PF00982.16 GAM24994.1 - 3.6e-117 391.7 0.0 5.5e-117 391.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM24994.1 - 2.2e-33 115.1 0.0 3.4e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Rad60-SLD PF11976.3 GAM24995.1 - 1.5e-26 91.8 1.4 1.1e-14 53.8 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like CYTH PF01928.16 GAM24995.1 - 0.025 14.2 0.8 1.3 8.6 0.2 2.5 2 1 0 2 2 2 0 CYTH domain AT_hook PF02178.14 GAM24995.1 - 0.32 10.8 4.3 0.67 9.8 3.0 1.6 1 0 0 1 1 1 0 AT hook motif MFS_1 PF07690.11 GAM24996.1 - 8e-30 103.7 28.2 1.1e-28 100.0 14.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM24996.1 - 2.7e-21 75.4 14.7 2.7e-21 75.4 10.2 1.7 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 GAM24996.1 - 1.9e-12 46.5 26.8 1.5e-06 27.1 13.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 GAM24996.1 - 0.015 13.4 6.2 0.45 8.5 3.7 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector MFS_2 PF13347.1 GAM24997.1 - 2.4e-96 322.7 28.9 2.9e-96 322.4 20.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 GAM24997.1 - 9.1e-18 64.0 29.1 9.1e-18 64.0 20.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily AATase PF07247.7 GAM24998.1 - 1.5e-08 33.6 0.0 2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase zf-C3H1 PF10650.4 GAM24999.1 - 1.3e-07 30.9 0.3 2.5e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain DUF489 PF04356.7 GAM24999.1 - 0.03 13.9 3.7 0.092 12.3 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF3373 PF11853.3 GAM24999.1 - 0.035 12.6 2.3 0.067 11.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) TPR_11 PF13414.1 GAM24999.1 - 0.041 13.5 0.1 0.17 11.5 0.1 2.2 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.1 GAM24999.1 - 0.048 13.8 3.2 0.14 12.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 GAM25000.1 - 9.7e-44 149.3 0.0 1.6e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM25000.1 - 1.4e-43 148.8 0.0 2.8e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 GAM25000.1 - 8.7e-06 24.8 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM25000.1 - 0.00011 22.0 0.0 0.00031 20.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Gin PF10764.4 GAM25000.1 - 0.026 14.2 2.5 0.055 13.1 0.6 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin PIP49_C PF12260.3 GAM25000.1 - 0.032 13.6 1.6 0.036 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 CPSF73-100_C PF11718.3 GAM25000.1 - 3.6 6.8 8.0 0.33 10.2 2.2 1.6 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term PHD PF00628.24 GAM25001.1 - 5.6e-12 45.1 11.4 1.7e-11 43.6 7.9 1.9 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 GAM25001.1 - 0.16 11.4 14.7 0.17 11.3 0.7 3.6 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain Ipi1_N PF12333.3 GAM25002.1 - 8.8e-16 57.7 1.3 8.8e-16 57.7 0.9 3.8 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 GAM25002.1 - 0.043 14.2 0.0 0.6 10.5 0.1 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Actin PF00022.14 GAM25003.1 - 8.7e-89 297.6 0.0 1.2e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Actin PH_3 PF14593.1 GAM25003.1 - 0.062 13.1 0.3 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 PH domain MreB_Mbl PF06723.8 GAM25003.1 - 0.078 11.5 0.0 5.1 5.6 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein adh_short PF00106.20 GAM25004.1 - 1.4e-30 106.4 0.1 2.9e-30 105.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM25004.1 - 2.9e-16 59.9 0.0 3.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM25004.1 - 4.6e-10 39.4 0.0 1.6e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM25004.1 - 3.5e-05 23.8 0.1 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 GAM25004.1 - 0.00042 19.4 0.7 0.0016 17.5 0.1 2.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 GAM25004.1 - 0.0042 17.1 0.1 0.1 12.7 0.1 2.6 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 GAM25004.1 - 0.0056 16.4 0.3 0.011 15.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 GAM25004.1 - 0.0073 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 GAM25004.1 - 0.022 14.2 0.1 0.052 12.9 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 GAM25004.1 - 0.079 12.5 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_Gly3P_dh_N PF01210.18 GAM25004.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 GAM25004.1 - 0.11 12.1 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RhoGAP PF00620.22 GAM25005.1 - 1.2e-22 80.2 1.7 4.8e-22 78.2 0.0 2.7 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.18 GAM25005.1 - 1.4e-12 47.6 1.3 1.4e-12 47.6 0.9 2.6 3 1 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain BRE1 PF08647.6 GAM25005.1 - 0.001 19.0 3.1 0.001 19.0 2.2 2.2 3 0 0 3 3 3 1 BRE1 E3 ubiquitin ligase DUF3439 PF11921.3 GAM25005.1 - 0.023 14.4 6.2 0.073 12.8 4.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3450 PF11932.3 GAM25005.1 - 0.055 12.7 1.6 0.12 11.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 GAM25005.1 - 0.26 10.2 10.8 0.044 12.8 3.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Tup_N PF08581.5 GAM25005.1 - 0.85 9.8 6.3 0.27 11.4 1.6 2.2 1 1 1 2 2 2 0 Tup N-terminal GAS PF13851.1 GAM25005.1 - 3.7 6.6 16.8 0.38 9.9 8.2 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 GAM25005.1 - 8.3 6.1 16.3 2.3 7.9 7.6 2.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FNIP PF05725.7 GAM25006.1 - 1.1e-39 134.0 0.2 7.6e-11 41.7 0.0 7.9 8 1 1 9 9 9 5 FNIP Repeat LRR_6 PF13516.1 GAM25006.1 - 0.011 15.6 0.7 8.4 6.8 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat MHC_II_beta PF00969.14 GAM25006.1 - 0.15 12.0 1.2 0.42 10.6 0.0 2.3 3 0 0 3 3 3 0 Class II histocompatibility antigen, beta domain Sld5 PF05916.6 GAM25007.1 - 1.7e-05 25.0 1.8 3e-05 24.2 1.2 1.5 1 1 0 1 1 1 1 GINS complex protein RCC1 PF00415.13 GAM25008.1 - 1.2e-67 223.8 9.2 1.8e-13 50.4 0.0 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM25008.1 - 1.2e-38 129.8 22.5 1.3e-08 34.2 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAM25008.1 - 2.3e-22 79.0 0.2 1e-15 57.6 0.1 3.0 2 1 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.1 GAM25008.1 - 5.5e-08 32.8 0.1 2.1e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM25008.1 - 2.1e-07 31.1 0.1 5.5e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25008.1 - 2e-05 24.9 0.0 0.0013 19.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM25008.1 - 7e-05 22.4 0.1 0.00053 19.6 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 GAM25008.1 - 0.00011 22.1 0.1 0.019 15.1 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat DUF3360 PF11840.3 GAM25008.1 - 0.13 10.6 0.0 0.25 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) CBM_X PF06204.6 GAM25008.1 - 0.76 9.3 4.7 18 4.9 0.1 3.7 5 0 0 5 5 5 0 Putative carbohydrate binding domain TALPID3 PF15324.1 GAM25009.1 - 0.11 9.8 0.7 0.12 9.7 0.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target HSF_DNA-bind PF00447.12 GAM25010.1 - 3.7e-29 100.9 0.7 3.7e-29 100.9 0.5 3.3 3 2 1 4 4 4 1 HSF-type DNA-binding FNIP PF05725.7 GAM25012.1 - 7e-62 205.1 20.0 1.4e-11 44.1 0.2 7.1 5 1 2 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM25012.1 - 4.5e-05 23.2 8.9 0.6 10.1 0.2 6.6 2 2 6 8 8 8 3 Protein of unknown function (DUF1769) Trypsin PF00089.21 GAM25013.1 - 3e-18 66.2 0.0 7.5e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 GAM25013.1 - 4.1e-16 59.0 0.1 8.9e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 GAM25013.1 - 4.4e-12 45.7 1.5 2.1e-10 40.3 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 GAM25013.1 - 0.0015 18.6 2.6 0.032 14.4 0.1 2.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) YscJ_FliF PF01514.12 GAM25014.1 - 0.00013 21.1 0.9 0.00018 20.7 0.7 1.3 1 1 0 1 1 1 1 Secretory protein of YscJ/FliF family DUF1160 PF06648.6 GAM25014.1 - 0.01 15.5 1.1 0.012 15.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) DUF3452 PF11934.3 GAM25014.1 - 0.012 14.9 0.6 0.015 14.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) SRPRB PF09439.5 GAM25014.1 - 0.027 13.6 1.1 0.033 13.4 0.8 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Epsilon_antitox PF08998.6 GAM25014.1 - 0.045 13.7 2.3 0.068 13.1 1.5 1.4 1 1 0 1 1 1 0 Bacterial epsilon antitoxin ROS_MUCR PF05443.6 GAM25014.1 - 0.061 13.0 0.2 0.27 10.9 0.0 1.9 1 1 1 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF948 PF06103.6 GAM25014.1 - 0.13 12.1 2.4 0.23 11.3 1.4 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SNF2_N PF00176.18 GAM25015.1 - 9.4e-81 270.8 0.0 9.4e-81 270.8 0.0 2.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain SLIDE PF09111.5 GAM25015.1 - 1.8e-37 127.6 5.7 1.8e-37 127.6 3.9 2.5 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.26 GAM25015.1 - 4.4e-14 52.0 0.0 1.7e-13 50.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HAND PF09110.6 GAM25015.1 - 2.3e-08 34.4 11.3 2.3e-08 34.4 7.8 5.7 4 2 0 4 4 4 1 HAND DBINO PF13892.1 GAM25015.1 - 0.00025 21.0 11.3 0.00025 21.0 7.8 4.1 4 1 1 5 5 5 1 DNA-binding domain Myb_DNA-binding PF00249.26 GAM25015.1 - 0.018 15.0 0.1 7.6 6.6 0.0 3.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain UDPGP PF01704.13 GAM25016.1 - 8.8e-49 166.1 0.1 1.2e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 GAM25016.1 - 0.084 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain adh_short PF00106.20 GAM25017.1 - 9.1e-28 97.2 0.3 1.3e-27 96.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM25017.1 - 1.5e-15 57.6 0.0 2.1e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM25017.1 - 4.6e-09 36.2 0.1 7.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM25017.1 - 4.8e-06 26.6 0.1 4e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 GAM25017.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 GAM25017.1 - 0.00039 19.4 0.0 0.00079 18.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 GAM25017.1 - 0.00051 19.5 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 GAM25017.1 - 0.0085 15.8 0.1 0.068 12.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 GAM25017.1 - 0.056 12.9 0.1 0.15 11.5 0.1 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.14 GAM25017.1 - 0.081 11.6 1.0 0.092 11.4 0.1 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NUDIX PF00293.23 GAM25018.1 - 1.2e-21 76.7 0.1 1.9e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF3661 PF12400.3 GAM25019.1 - 0.85 9.7 5.4 0.44 10.6 1.7 1.8 2 0 0 2 2 2 0 Vaculolar membrane protein Bromodomain PF00439.20 GAM25020.1 - 2.1e-16 59.6 0.0 4.3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 GAM25020.1 - 4.2e-10 39.6 0.8 9.3e-10 38.5 0.5 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM25020.1 - 8.4e-09 35.3 0.1 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DYW_deaminase PF14432.1 GAM25020.1 - 0.009 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases RabGAP-TBC PF00566.13 GAM25021.1 - 7.7e-35 120.3 0.1 1.2e-34 119.7 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain XkdN PF08890.6 GAM25021.1 - 0.14 11.8 0.1 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Phage XkdN-like protein Syntaxin_2 PF14523.1 GAM25021.1 - 0.16 12.0 1.7 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Syntaxin-like protein AAA_23 PF13476.1 GAM25022.1 - 0.99 9.6 10.9 1.2 9.4 7.5 1.1 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 GAM25023.1 - 4.7e-23 81.1 0.0 9.5e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.13 GAM25023.1 - 0.0031 16.5 0.2 0.0053 15.8 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RWD PF05773.17 GAM25023.1 - 0.031 14.1 0.0 0.031 14.1 0.0 2.6 2 1 0 2 2 2 0 RWD domain DUF2452 PF10504.4 GAM25023.1 - 0.55 9.5 2.7 1.3 8.3 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) DUF3439 PF11921.3 GAM25023.1 - 6.6 6.4 25.5 1.4 8.7 6.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) TFIIA PF03153.8 GAM25023.1 - 7.2 6.4 18.1 10 5.9 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_4 PF12799.2 GAM25024.1 - 4.7e-15 54.8 13.5 3.5e-08 32.8 0.2 2.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 GAM25024.1 - 3.1e-10 39.8 0.4 4.7e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 GAM25024.1 - 1.3e-09 37.6 15.4 7.9e-07 28.7 5.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 GAM25024.1 - 2.2e-06 26.9 5.6 0.58 10.5 0.0 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 GAM25024.1 - 6.4e-06 25.4 11.3 0.62 10.3 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.1 GAM25024.1 - 0.0032 17.3 10.9 4 7.8 0.1 4.6 4 0 0 4 4 4 1 Leucine Rich repeat DUF3439 PF11921.3 GAM25024.1 - 0.016 14.9 3.0 0.029 14.1 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM25024.1 - 0.04 13.6 13.4 0.064 13.0 9.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_L37ae PF01780.14 GAM25025.1 - 3.7e-40 135.6 8.0 4e-40 135.5 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 GAM25025.1 - 0.0026 17.5 1.8 0.0037 17.0 1.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 GAM25025.1 - 0.0051 16.2 1.8 0.97 8.9 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain zf-C4_ClpX PF06689.8 GAM25025.1 - 0.072 12.6 0.2 0.072 12.6 0.1 1.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger DUF1364 PF07102.7 GAM25025.1 - 0.088 12.6 0.6 0.12 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) OrfB_Zn_ribbon PF07282.6 GAM25025.1 - 0.094 12.3 0.8 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-FCS PF06467.9 GAM25025.1 - 0.12 12.0 1.1 2.9 7.5 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 GAM25025.1 - 0.19 12.0 0.6 1.6 9.1 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 GAM25025.1 - 0.21 11.5 1.3 0.49 10.3 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain F-box PF00646.28 GAM25026.1 - 5.5e-06 25.8 2.8 2.5e-05 23.7 1.9 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM25026.1 - 1.4e-05 24.7 0.8 3.2e-05 23.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.1 GAM25026.1 - 0.00056 20.0 0.0 0.0018 18.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PHAT PF09246.5 GAM25026.1 - 0.0055 16.3 0.0 0.02 14.5 0.0 1.9 1 0 0 1 1 1 1 PHAT CTD_bind PF04818.8 GAM25026.1 - 0.01 16.0 0.1 0.089 13.0 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Ank_2 PF12796.2 GAM25026.1 - 0.019 15.2 0.1 0.082 13.2 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) bZIP_1 PF00170.16 GAM25027.1 - 4.9e-08 32.8 15.8 1.3e-07 31.4 11.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 GAM25027.1 - 9.2e-08 32.2 11.3 9.2e-08 32.2 7.8 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor bZIP_2 PF07716.10 GAM25027.1 - 0.00014 21.6 11.2 0.00014 21.6 7.8 2.3 2 1 1 3 3 3 1 Basic region leucine zipper THOC7 PF05615.8 GAM25027.1 - 1.5 9.1 14.9 0.48 10.6 8.2 1.7 2 0 0 2 2 2 0 Tho complex subunit 7 Thiolase_N PF00108.18 GAM25028.1 - 1.1e-91 306.4 0.0 1.6e-91 305.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 GAM25028.1 - 2.2e-44 149.8 0.9 6.1e-44 148.3 0.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 GAM25028.1 - 0.00048 19.6 0.3 0.0024 17.3 0.2 1.9 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 GAM25028.1 - 0.027 14.3 0.5 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Glutaredoxin PF00462.19 GAM25029.1 - 3.6e-18 65.2 0.0 1.3e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 GAM25029.1 - 1.4e-13 50.4 0.2 3.3e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 GAM25029.1 - 2.6e-05 24.2 1.5 0.00062 19.8 0.1 3.0 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM25029.1 - 0.00018 21.6 0.3 0.17 12.0 0.0 3.2 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 GAM25029.1 - 0.00042 20.0 0.0 0.0038 16.9 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.16 GAM25029.1 - 0.0006 19.4 1.0 0.0084 15.7 0.0 2.8 2 2 1 3 3 3 1 AhpC/TSA family Thioredoxin_9 PF14595.1 GAM25029.1 - 0.0069 15.9 0.8 0.088 12.3 0.1 2.5 1 1 0 2 2 2 1 Thioredoxin XH PF03469.9 GAM25029.1 - 0.0081 15.8 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 XH domain HyaE PF07449.6 GAM25029.1 - 0.033 14.0 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 GAM25029.1 - 0.033 14.1 0.1 1.1 9.2 0.1 2.6 2 1 0 2 2 2 0 Thioredoxin-like DUF393 PF04134.7 GAM25030.1 - 1.2e-24 87.6 0.1 1.5e-24 87.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF2428 PF10350.4 GAM25031.1 - 1.3e-60 204.5 0.0 4.8e-60 202.7 0.0 2.1 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 GAM25031.1 - 4.7e-07 30.0 1.5 2.6 8.3 0.0 5.9 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.17 GAM25031.1 - 2.2e-06 27.2 1.6 0.12 12.5 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 GAM25031.1 - 0.0045 17.4 0.1 17 6.0 0.1 5.7 5 0 0 5 5 5 1 HEAT-like repeat DNA_pol_B_2 PF03175.8 GAM25032.1 - 7e-06 24.9 5.3 0.00015 20.5 3.6 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral AAA_22 PF13401.1 GAM25034.1 - 0.0097 16.0 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM25034.1 - 0.036 14.0 0.0 0.09 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain RE_CfrBI PF09516.5 GAM25034.1 - 0.13 11.0 0.0 0.86 8.4 0.0 2.0 2 0 0 2 2 2 0 CfrBI restriction endonuclease FNIP PF05725.7 GAM25035.1 - 3.2e-31 107.0 11.8 4.6e-15 55.2 0.0 6.7 5 2 0 5 5 5 5 FNIP Repeat 7tm_2 PF00002.19 GAM25036.1 - 9.7e-07 28.1 7.4 2.2e-06 26.9 5.1 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 GAM25036.1 - 1.2e-05 24.4 15.3 3.3e-05 22.9 10.6 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.12 GAM25036.1 - 0.0037 16.0 8.4 0.15 10.8 3.5 2.3 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Git3_C PF11970.3 GAM25036.1 - 0.019 14.7 0.1 0.064 13.0 0.1 1.9 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term EpsG PF14897.1 GAM25036.1 - 0.076 11.9 14.5 0.093 11.6 5.5 2.1 2 0 0 2 2 2 0 EpsG family DUF1435 PF07256.7 GAM25036.1 - 0.1 12.6 3.4 8.3 6.4 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Syndecan PF01034.15 GAM25036.1 - 0.11 12.2 0.1 24 4.6 0.0 2.6 2 0 0 2 2 2 0 Syndecan domain DUF2304 PF10066.4 GAM25036.1 - 0.26 11.1 5.8 0.16 11.8 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) GATA PF00320.22 GAM25037.1 - 4.6e-16 57.8 3.5 8.7e-16 56.9 2.4 1.5 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 GAM25037.1 - 6.2 6.7 7.1 4.1 7.3 2.5 2.4 2 1 0 2 2 2 0 Double zinc ribbon Pacs-1 PF10254.4 GAM25038.1 - 5.5e-30 104.3 3.8 5.5e-30 104.3 2.6 4.3 2 1 1 3 3 3 1 PACS-1 cytosolic sorting protein Serglycin PF04360.7 GAM25038.1 - 0.069 12.8 14.0 0.012 15.3 2.3 4.0 4 0 0 4 4 4 0 Serglycin Gly-zipper_OmpA PF13436.1 GAM25038.1 - 0.97 9.1 8.7 0.73 9.5 3.3 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain SKG6 PF08693.5 GAM25039.1 - 0.015 14.6 4.2 0.032 13.5 2.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 GAM25039.1 - 0.026 14.0 0.4 0.05 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EGF_2 PF07974.8 GAM25039.1 - 0.04 14.0 16.1 0.091 12.9 11.2 1.6 1 0 0 1 1 1 0 EGF-like domain Polyketide_cyc PF03364.15 GAM25039.1 - 0.042 13.8 0.0 0.088 12.7 0.0 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport bZIP_2 PF07716.10 GAM25040.1 - 0.04 13.7 0.3 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Basic region leucine zipper A2M_N PF01835.14 GAM25041.1 - 8.1e-07 29.2 0.1 4.1e-06 26.9 0.1 2.3 1 0 0 1 1 1 1 MG2 domain A2M PF00207.17 GAM25041.1 - 8.5e-06 25.2 0.0 3e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 GAM25041.1 - 0.00011 22.0 0.2 0.0054 16.5 0.0 3.4 4 0 0 4 4 4 1 Alpha-2-macroglobulin family N-terminal region Glyco_transf_20 PF00982.16 GAM25042.1 - 1.6e-172 574.2 0.0 5.4e-172 572.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM25042.1 - 2.5e-39 134.5 0.0 4.7e-39 133.7 0.0 1.5 1 1 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 GAM25042.1 - 0.00022 20.6 2.0 0.00059 19.3 0.1 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 DRTGG PF07085.7 GAM25042.1 - 0.0097 15.4 0.1 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 DRTGG domain RabGAP-TBC PF00566.13 GAM25043.1 - 9e-57 191.9 2.0 7.8e-56 188.9 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 GAM25043.1 - 3.8e-20 71.1 3.1 5e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 GRAM domain bPH_2 PF03703.9 GAM25043.1 - 0.0034 17.3 0.2 0.037 14.0 0.0 2.5 3 0 0 3 3 3 1 Bacterial PH domain PHD_3 PF13922.1 GAM25043.1 - 0.29 11.3 3.9 15 5.9 0.6 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx CBFD_NFYB_HMF PF00808.18 GAM25044.1 - 5.1e-10 39.2 0.6 1.3e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNase_H2-Ydr279 PF09468.5 GAM25044.1 - 0.0044 16.2 10.8 0.0049 16.1 7.5 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Med17 PF10156.4 GAM25044.1 - 0.0081 14.4 5.1 0.0081 14.4 3.6 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Bromo_TP PF07524.8 GAM25044.1 - 0.011 15.4 0.1 0.08 12.6 0.0 2.0 1 1 1 2 2 2 0 Bromodomain associated Mucin PF01456.12 GAM25044.1 - 0.022 14.5 2.2 0.026 14.2 1.5 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DDHD PF02862.12 GAM25044.1 - 0.038 13.7 9.4 0.047 13.4 6.5 1.1 1 0 0 1 1 1 0 DDHD domain Na_K-ATPase PF00287.13 GAM25044.1 - 0.068 11.9 4.9 0.091 11.5 3.2 1.3 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain BRF1 PF07741.8 GAM25044.1 - 0.092 12.9 13.5 0.17 12.1 9.4 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Rtf2 PF04641.7 GAM25044.1 - 0.14 11.3 14.9 0.15 11.2 10.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Membralin PF09746.4 GAM25044.1 - 0.15 11.0 2.0 0.16 11.0 1.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein Sporozoite_P67 PF05642.6 GAM25044.1 - 0.34 8.7 10.7 0.39 8.5 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SHR3_chaperone PF08229.6 GAM25044.1 - 0.41 9.5 4.1 0.61 9.0 2.8 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 Casc1 PF12366.3 GAM25044.1 - 0.45 9.9 9.8 0.63 9.4 6.8 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Vfa1 PF08432.5 GAM25044.1 - 0.66 9.9 23.1 0.86 9.5 16.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.5 GAM25044.1 - 0.91 9.3 12.7 1.4 8.7 8.8 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Atrophin-1 PF03154.10 GAM25044.1 - 1.2 7.1 12.6 1.5 6.8 8.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Paramyxo_ncap PF00973.14 GAM25044.1 - 1.3 7.5 6.0 1.3 7.6 4.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1510 PF07423.6 GAM25044.1 - 1.5 8.1 19.4 1.7 7.9 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 GAM25044.1 - 1.9 6.4 12.4 2 6.3 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Rsc14 PF08586.5 GAM25044.1 - 2.8 8.4 6.7 4.4 7.8 4.0 1.8 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit YABBY PF04690.8 GAM25044.1 - 3.3 7.9 6.7 12 6.1 0.1 2.1 2 0 0 2 2 2 0 YABBY protein RP-C_C PF11800.3 GAM25044.1 - 6.1 6.4 7.8 7.5 6.1 5.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Mlo PF03094.10 GAM25044.1 - 6.6 4.7 6.5 9.9 4.1 4.5 1.2 1 0 0 1 1 1 0 Mlo family DUF3987 PF13148.1 GAM25044.1 - 8.3 4.8 10.2 13 4.2 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MATH PF00917.21 GAM25045.1 - 1.3e-07 31.8 0.1 4.2e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 MATH domain Mycoplasma_p37 PF06646.6 GAM25045.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 Beta-lactamase PF00144.19 GAM25046.1 - 0.19 10.7 0.0 0.28 10.1 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase vATP-synt_E PF01991.13 GAM25047.1 - 7.9e-64 214.5 4.4 9.2e-64 214.3 3.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DivIVA PF05103.8 GAM25047.1 - 3.4 7.7 15.8 8.3 6.4 3.7 2.3 1 1 1 2 2 2 0 DivIVA protein SKG6 PF08693.5 GAM25048.1 - 0.015 14.5 1.7 0.38 10.1 0.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Flavi_NS4A PF01350.12 GAM25048.1 - 0.075 12.5 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Ribonuclease_3 PF00636.21 GAM25049.1 - 0.00013 22.4 1.0 0.00022 21.6 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Rapamycin_bind PF08771.6 GAM25049.1 - 0.0046 17.0 1.0 0.0094 16.0 0.7 1.5 1 0 0 1 1 1 1 Rapamycin binding domain Ribonuclease_3 PF00636.21 GAM25050.1 - 7.9e-07 29.5 0.3 3.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 GAM25050.1 - 0.00094 19.1 4.1 0.003 17.4 0.0 2.7 2 1 0 2 2 2 1 Ribonuclease-III-like DUF1818 PF08848.6 GAM25050.1 - 0.11 12.5 2.1 0.36 10.9 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) Lamp PF01299.12 GAM25050.1 - 0.23 10.5 5.4 0.87 8.6 0.3 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Ribosomal_L23 PF00276.15 GAM25051.1 - 4.8e-13 48.8 5.3 7e-13 48.3 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RusA PF05866.6 GAM25051.1 - 0.059 13.7 2.0 0.19 12.1 1.1 1.9 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA DUF2723 PF11028.3 GAM25052.1 - 4.5e-39 133.7 8.7 4.5e-39 133.7 6.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) DdrB PF12747.2 GAM25052.1 - 0.03 14.0 0.1 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 DdrB-like protein zf-MYND PF01753.13 GAM25053.1 - 6.5e-08 32.3 11.9 6.5e-08 32.3 8.3 4.8 2 1 0 3 3 3 1 MYND finger F-box PF00646.28 GAM25054.1 - 0.0014 18.1 0.4 0.026 14.1 0.5 2.9 2 0 0 2 2 2 1 F-box domain ACOX PF01756.14 GAM25056.1 - 4.7e-13 48.9 0.0 8.2e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAM25056.1 - 2.3e-10 39.8 0.0 4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM25056.1 - 1.7e-08 34.6 0.0 4e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 GAM25056.1 - 2.2e-06 27.9 0.2 4.6e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.11 GAM25056.1 - 0.017 15.6 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Cut8_C PF08559.5 GAM25057.1 - 2.9e-12 46.6 0.6 2.9e-12 46.6 0.4 2.8 2 1 0 2 2 2 1 Cut8 six-helix bundle DSHCT PF08148.7 GAM25057.1 - 0.24 10.6 3.3 0.29 10.3 0.0 2.3 2 0 0 2 2 2 0 DSHCT (NUC185) domain Med15 PF09606.5 GAM25057.1 - 0.5 8.4 58.6 0.69 8.0 40.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.15 GAM25057.1 - 6.8 4.8 9.2 9.8 4.3 6.3 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4175 PF13779.1 GAM25057.1 - 7.8 4.0 41.0 12 3.4 28.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CtaG_Cox11 PF04442.9 GAM25058.1 - 7.2e-55 184.9 0.1 7.2e-55 184.9 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Pex14_N PF04695.8 GAM25058.1 - 0.00084 19.3 5.9 0.0014 18.6 4.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 GAM25058.1 - 0.0021 16.1 1.6 0.0027 15.8 1.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Suf PF05843.9 GAM25058.1 - 0.025 14.3 4.8 0.034 13.8 3.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 GAM25058.1 - 0.054 12.4 0.6 0.07 12.1 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.10 GAM25058.1 - 0.063 11.9 1.3 0.083 11.5 0.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SR-25 PF10500.4 GAM25058.1 - 0.077 12.4 11.5 0.11 11.8 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF350 PF03994.9 GAM25058.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF350) BORG_CEP PF14957.1 GAM25058.1 - 0.15 12.9 6.1 0.24 12.3 4.2 1.2 1 0 0 1 1 1 0 Cdc42 effector WBS_methylT PF12589.3 GAM25058.1 - 0.16 12.4 12.7 0.26 11.8 8.8 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome API5 PF05918.6 GAM25058.1 - 0.19 10.1 6.3 0.26 9.7 4.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) IncA PF04156.9 GAM25058.1 - 0.51 9.9 7.2 0.78 9.3 5.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4557 PF15101.1 GAM25058.1 - 0.51 10.1 9.0 0.71 9.6 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2201_N PF13203.1 GAM25058.1 - 0.61 9.1 10.2 0.86 8.7 7.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 GAM25058.1 - 0.7 8.6 6.1 0.97 8.2 4.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4407 PF14362.1 GAM25058.1 - 0.77 8.6 3.6 1.1 8.1 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 GAM25058.1 - 2.5 7.8 8.7 3.6 7.3 6.0 1.2 1 0 0 1 1 1 0 DDHD domain G0-G1_switch_2 PF15103.1 GAM25058.1 - 2.6 8.3 8.0 16 5.8 3.9 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Pex16 PF08610.5 GAM25058.1 - 4 6.3 8.3 5.6 5.8 5.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Herpes_DNAp_acc PF04929.7 GAM25058.1 - 4.7 6.0 8.2 6.5 5.6 5.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor UPF0560 PF10577.4 GAM25058.1 - 5.7 5.0 11.5 7.4 4.6 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF912 PF06024.7 GAM25058.1 - 5.9 7.0 8.5 14 5.7 5.9 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 GAM25058.1 - 6.3 4.3 9.5 8 3.9 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.8 GAM25058.1 - 6.5 6.1 8.4 9.3 5.6 5.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FimP PF09766.4 GAM25058.1 - 6.8 5.6 18.0 16 4.3 12.6 1.5 2 0 0 2 2 2 0 Fms-interacting protein UPF0121 PF03661.8 GAM25059.1 - 2.7e-19 69.3 5.5 3.7e-19 68.9 3.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Pex14_N PF04695.8 GAM25059.1 - 0.0023 17.9 9.6 0.0047 16.9 6.7 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.6 GAM25059.1 - 0.011 15.0 0.1 0.014 14.5 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.10 GAM25059.1 - 0.014 14.7 0.6 0.017 14.3 0.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.1 GAM25059.1 - 0.051 13.3 2.9 0.075 12.7 2.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Suf PF05843.9 GAM25059.1 - 0.15 11.7 8.3 0.22 11.1 5.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2360 PF10152.4 GAM25059.1 - 0.26 11.5 6.1 0.42 10.9 4.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4282 PF14110.1 GAM25059.1 - 0.59 10.3 5.8 0.26 11.4 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Shisa PF13908.1 GAM25059.1 - 1.6 8.9 10.1 2.8 8.0 7.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Gemini_mov PF01708.11 GAM25059.1 - 3.2 7.3 10.7 0.26 10.8 1.0 3.3 3 1 1 4 4 4 0 Geminivirus putative movement protein DUF605 PF04652.11 GAM25059.1 - 3.3 6.9 21.4 4.7 6.5 14.8 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_DNAp_acc PF04929.7 GAM25059.1 - 7.5 5.3 10.7 9.8 5.0 7.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor EGF_2 PF07974.8 GAM25060.1 - 0.059 13.5 9.3 0.13 12.3 6.4 1.6 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 GAM25061.1 - 6.9e-20 70.8 40.7 2.5e-06 27.4 1.7 5.9 4 2 1 5 5 5 4 IPT/TIG domain EGF_2 PF07974.8 GAM25061.1 - 1.4e-05 25.1 13.8 3.6e-05 23.8 9.6 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.22 GAM25061.1 - 0.0022 17.9 10.6 0.0055 16.6 7.4 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM25061.1 - 0.0099 15.8 2.5 0.026 14.5 1.7 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF CS PF04969.11 GAM25061.1 - 0.014 15.8 0.7 0.17 12.4 0.0 2.9 3 0 0 3 3 3 0 CS domain Toxin_2 PF00451.14 GAM25061.1 - 0.99 9.5 5.7 2.5 8.2 4.0 1.7 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 EGF_2 PF07974.8 GAM25062.1 - 0.00057 20.0 12.9 0.0013 18.8 9.0 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM25062.1 - 0.0037 17.2 2.8 0.0094 15.9 1.9 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.22 GAM25062.1 - 0.017 15.0 8.0 0.035 14.0 5.5 1.5 1 0 0 1 1 1 0 EGF-like domain SLY PF12485.3 GAM25062.1 - 0.07 13.3 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein TIG PF01833.19 GAM25063.1 - 5.5e-09 35.9 63.4 0.0005 20.0 1.0 7.5 5 2 2 7 7 7 5 IPT/TIG domain EGF_2 PF07974.8 GAM25063.1 - 0.00023 21.2 10.7 0.00057 19.9 7.4 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM25063.1 - 0.0043 17.0 1.4 0.0043 17.0 1.0 2.4 2 0 0 2 2 2 1 Human growth factor-like EGF EGF PF00008.22 GAM25063.1 - 0.021 14.7 9.8 0.061 13.3 6.8 1.8 1 0 0 1 1 1 0 EGF-like domain Sec3_C_2 PF15278.1 GAM25063.1 - 0.35 11.0 2.3 19 5.4 0.1 2.5 2 0 0 2 2 2 0 Sec3 exocyst complex subunit EB PF01683.13 GAM25063.1 - 1.6 8.8 9.9 12 6.1 5.5 2.5 2 0 0 2 2 2 0 EB module IPK PF03770.11 GAM25064.1 - 9.8e-37 126.5 1.0 9.8e-37 126.5 0.7 2.0 2 1 0 2 2 2 1 Inositol polyphosphate kinase RAB3GAP2_N PF14655.1 GAM25065.1 - 9e-119 397.1 0.0 2e-118 396.0 0.0 1.5 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus CMV_1a PF12467.3 GAM25065.1 - 1 9.6 10.6 2.2 8.6 7.4 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Sporozoite_P67 PF05642.6 GAM25065.1 - 1.7 6.4 16.8 2.7 5.7 9.8 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Trypan_PARP PF05887.6 GAM25065.1 - 2.1 8.1 8.3 0.35 10.6 2.9 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.1 GAM25065.1 - 2.5 7.7 11.3 56 3.3 0.0 2.6 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 GAM25065.1 - 6.1 6.3 17.1 6.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Nucleoplasmin SNF2_N PF00176.18 GAM25068.1 - 1.1e-59 201.7 0.0 2.1e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM25068.1 - 5.7e-11 42.1 0.0 3e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.24 GAM25068.1 - 1.2e-10 40.8 8.2 1.2e-10 40.8 5.7 2.5 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.1 GAM25068.1 - 1.5e-05 24.5 4.4 1.5e-05 24.5 3.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM25068.1 - 2.9e-05 23.6 7.6 2.9e-05 23.6 5.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM25068.1 - 3.2e-05 23.8 7.8 3.2e-05 23.8 5.4 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM25068.1 - 0.00029 20.6 6.2 0.00029 20.6 4.3 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAM25068.1 - 0.003 17.3 8.4 0.003 17.3 5.8 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM25068.1 - 0.022 14.4 3.7 0.069 12.8 2.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 GAM25068.1 - 4 7.6 13.0 0.43 10.7 3.2 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM25068.1 - 6 6.7 8.6 1.2 9.0 1.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.1 GAM25068.1 - 6.9 6.0 11.0 0.18 11.1 2.8 2.0 2 0 0 2 2 2 0 PHD-finger Dynamin_N PF00350.18 GAM25069.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FNIP PF05725.7 GAM25070.1 - 1.5e-65 216.8 25.5 6.5e-13 48.4 0.0 5.3 1 1 6 7 7 7 7 FNIP Repeat FNIP PF05725.7 GAM25071.1 - 3e-39 132.6 13.7 3.8e-11 42.7 0.1 6.1 3 1 2 6 6 6 6 FNIP Repeat FNIP PF05725.7 GAM25072.1 - 3.8e-45 151.5 12.2 1.7e-13 50.2 0.1 5.7 6 0 0 6 6 6 4 FNIP Repeat DUF1769 PF08588.5 GAM25072.1 - 0.00013 21.8 1.9 0.67 9.9 0.0 4.1 2 2 1 3 3 3 3 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM25073.1 - 3e-70 231.9 11.3 2.1e-13 49.9 0.1 6.2 1 1 5 8 8 8 8 FNIP Repeat F-box-like PF12937.2 GAM25073.1 - 2.7e-05 23.7 0.4 0.00015 21.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like FNIP PF05725.7 GAM25074.1 - 1.2e-61 204.4 14.8 6.3e-15 54.8 0.3 6.9 3 1 3 8 8 8 7 FNIP Repeat DUF3736 PF12540.3 GAM25075.1 - 0.036 14.3 0.3 0.1 12.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3736) HTH_31 PF13560.1 GAM25075.1 - 0.084 13.0 0.1 0.65 10.2 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain Pyridoxal_deC PF00282.14 GAM25076.1 - 5.5e-21 74.4 0.0 1.7e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAM25076.1 - 0.00022 20.0 0.0 0.00046 19.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V ubiquitin PF00240.18 GAM25078.1 - 9.5e-35 117.8 0.6 1.2e-34 117.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 GAM25078.1 - 5.1e-30 102.8 10.5 8.4e-30 102.1 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 GAM25078.1 - 1.7e-19 69.2 0.4 2.2e-19 68.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM25078.1 - 1.1e-05 25.5 0.1 4.1e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM25078.1 - 0.00093 18.9 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM25078.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM25078.1 - 0.047 13.8 0.1 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM25078.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Thioredoxin PF00085.15 GAM25079.1 - 1.2e-31 108.4 0.0 7.4e-15 54.5 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 GAM25079.1 - 1.4e-09 38.0 0.7 2.4e-07 30.7 0.1 3.3 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 GAM25079.1 - 9.1e-06 25.8 0.0 0.45 10.7 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 GAM25079.1 - 9.6e-06 25.5 0.1 0.011 15.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 GAM25079.1 - 0.0019 18.2 0.2 7.6 6.7 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 GAM25079.1 - 0.084 12.5 0.0 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family N2227 PF07942.7 GAM25080.1 - 1.4e-61 207.8 0.2 2.2e-61 207.1 0.1 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 GAM25080.1 - 0.0032 17.1 0.0 0.0084 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM25080.1 - 0.031 14.7 0.0 0.089 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain BUD22 PF09073.5 GAM25080.1 - 0.6 9.1 9.2 0.85 8.6 6.4 1.1 1 0 0 1 1 1 0 BUD22 Ground-like PF04155.13 GAM25080.1 - 2.2 8.6 5.6 14 6.0 0.2 3.3 3 0 0 3 3 3 0 Ground-like domain Tmemb_14 PF03647.8 GAM25081.1 - 8.6e-24 83.7 8.3 9.7e-24 83.5 5.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Glug PF07581.7 GAM25081.1 - 0.088 13.0 0.3 19 5.7 0.0 2.6 2 0 0 2 2 2 0 The GLUG motif zf-RING_6 PF14835.1 GAM25082.1 - 8.9e-05 22.2 1.4 0.00021 21.0 1.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 GAM25082.1 - 0.0011 18.6 1.3 0.0035 17.0 0.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 GAM25082.1 - 0.0016 18.0 5.6 0.0047 16.5 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM25082.1 - 0.0085 15.9 4.4 0.0085 15.9 3.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 GAM25082.1 - 0.01 15.8 8.2 0.1 12.6 5.9 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 GAM25082.1 - 0.011 15.3 0.8 0.22 11.1 0.0 2.4 2 0 0 2 2 2 0 Seven in absentia protein family zf-C3HC4 PF00097.20 GAM25082.1 - 0.014 15.0 5.0 0.059 13.0 3.5 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4482 PF14818.1 GAM25082.1 - 0.024 15.2 0.8 0.024 15.2 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) DUF4653 PF15546.1 GAM25082.1 - 0.98 8.6 10.0 5 6.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) zf-RING_2 PF13639.1 GAM25082.1 - 6 6.7 14.2 0.089 12.6 4.2 2.2 3 0 0 3 3 3 0 Ring finger domain zf-RING_5 PF14634.1 GAM25082.1 - 7.1 6.4 15.2 0.14 11.9 5.3 2.1 2 0 0 2 2 1 0 zinc-RING finger domain Got1 PF04178.7 GAM25083.1 - 8.3e-29 100.0 16.0 1.3e-28 99.4 11.1 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.3 GAM25083.1 - 0.73 9.9 6.1 20 5.3 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) Claudin_2 PF13903.1 GAM25083.1 - 1.7 8.3 13.6 0.077 12.6 0.6 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Alg14 PF08660.6 GAM25084.1 - 2.1e-58 197.0 0.0 4.4e-58 196.0 0.0 1.5 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 GAM25084.1 - 1.4e-16 60.6 0.4 3.6e-16 59.2 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain VARLMGL PF14383.1 GAM25084.1 - 0.13 11.4 0.1 0.26 10.4 0.1 1.5 1 0 0 1 1 1 0 DUF761-associated sequence motif FKBP_C PF00254.23 GAM25085.1 - 1.5e-35 121.1 0.0 1.8e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2731 PF10806.3 GAM25086.1 - 0.016 15.4 2.0 0.023 14.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2731) CNF1 PF05785.7 GAM25086.1 - 0.038 12.8 0.0 0.05 12.5 0.0 1.1 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor Slp PF03843.8 GAM25086.1 - 0.061 12.3 4.3 0.11 11.4 3.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family Suf PF05843.9 GAM25086.1 - 3.7 7.1 10.4 4.5 6.9 7.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAM PF15320.1 GAM25086.1 - 7.9 6.8 11.1 7.8 6.8 6.9 1.6 1 1 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein BAF1_ABF1 PF04684.8 GAM25086.1 - 9 5.0 33.0 11 4.7 22.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NDT80_PhoG PF05224.7 GAM25087.1 - 1.2e-22 80.8 2.6 4.3e-21 75.7 0.1 2.6 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 GAM25088.1 - 1.2e-10 41.3 1.3 1.4e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Chaperone of endosialidase MRF_C1 PF13887.1 GAM25088.1 - 3e-08 32.5 0.0 3e-08 32.5 0.0 2.5 3 0 0 3 3 3 1 Myelin gene regulatory factor -C-terminal domain 1 ACCA PF03255.9 GAM25088.1 - 0.12 11.8 3.8 3.2 7.2 1.4 2.1 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PEMT PF04191.8 GAM25091.1 - 4.3e-30 103.9 5.6 1e-29 102.7 3.9 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4605 PF15378.1 GAM25091.1 - 5.7 6.7 5.9 1.4 8.6 0.9 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4605) Ras PF00071.17 GAM25092.1 - 4.2e-64 214.8 0.3 4.9e-64 214.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM25092.1 - 1.3e-21 77.3 0.0 1.9e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM25092.1 - 2e-18 66.2 0.2 2.4e-18 66.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM25092.1 - 1.5e-07 30.8 0.1 1.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM25092.1 - 1.5e-06 27.8 0.3 3.8e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM25092.1 - 2.5e-05 24.1 0.1 4.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM25092.1 - 4.5e-05 22.7 0.0 7.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 GAM25092.1 - 0.0013 18.9 0.0 0.65 10.1 0.0 2.3 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 GAM25092.1 - 0.0015 17.8 0.1 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 GAM25092.1 - 0.0021 17.2 0.1 0.0077 15.4 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 GAM25092.1 - 0.0053 15.4 3.0 0.33 9.6 0.4 2.9 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.1 GAM25092.1 - 0.0086 16.0 0.0 0.024 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM25092.1 - 0.0094 16.0 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 GAM25092.1 - 0.032 13.7 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 GAM25092.1 - 0.056 12.4 0.1 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Septin NACHT PF05729.7 GAM25092.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 GAM25092.1 - 0.092 13.0 0.2 0.14 12.4 0.1 1.6 1 1 0 1 1 1 0 ABC transporter BTG PF07742.7 GAM25093.1 - 1.5e-17 63.1 0.0 2.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 BTG family RRM_5 PF13893.1 GAM25093.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HUN PF08729.5 GAM25094.1 - 3.7e-09 36.3 5.9 3.7e-09 36.3 4.1 3.5 2 0 0 2 2 2 1 HPC2 and ubinuclein domain RhoGAP PF00620.22 GAM25096.1 - 7e-32 110.1 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain SKG6 PF08693.5 GAM25096.1 - 0.00063 18.9 0.7 0.0012 18.0 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 GAM25096.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ribosomal_L3 PF00297.17 GAM25097.1 - 1e-116 388.9 4.8 1.3e-116 388.5 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2042 PF09743.4 GAM25097.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2042) Dyp_perox PF04261.7 GAM25099.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family DUF2341 PF10102.4 GAM25099.1 - 5 7.3 6.1 0.59 10.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) Mycobact_memb PF05423.8 GAM25100.1 - 0.016 14.9 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Mycobacterium membrane protein MAGE_N PF12440.3 GAM25100.1 - 0.57 10.4 15.1 0.066 13.5 5.6 2.8 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal FNIP PF05725.7 GAM25101.1 - 1.5e-38 130.4 3.2 1.8e-07 30.9 0.0 6.7 4 3 1 6 6 6 5 FNIP Repeat Ribosomal_L30 PF00327.15 GAM25102.1 - 4.4e-19 67.8 0.9 4.4e-19 67.8 0.6 2.1 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 GAM25102.1 - 4.5e-18 65.0 11.2 8.3e-18 64.1 7.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Elong_Iki1 PF10483.4 GAM25103.1 - 5.3e-16 58.8 7.1 2.3e-13 50.1 4.9 2.5 1 1 0 1 1 1 1 Elongator subunit Iki1 UCH PF00443.24 GAM25105.1 - 8e-59 198.9 0.3 1.2e-58 198.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 GAM25105.1 - 1.2e-53 181.9 0.1 2.9e-53 180.6 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 GAM25105.1 - 6.1e-40 136.9 1.0 1.3e-24 86.8 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 GAM25105.1 - 4.9e-32 111.5 0.0 1.3e-31 110.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 GAM25105.1 - 1.7e-13 50.8 0.3 1.7e-13 50.8 0.2 2.8 3 0 0 3 3 3 1 MATH domain Ubiquitin_2 PF14560.1 GAM25105.1 - 0.012 15.8 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain HATPase_c PF02518.21 GAM25106.1 - 2.1e-23 82.1 0.1 1e-22 79.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM25106.1 - 2.9e-19 69.1 0.1 1e-18 67.3 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM25106.1 - 8e-19 67.4 0.1 1.8e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 GAM25106.1 - 2.5e-05 24.6 0.0 5.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 GAM25106.1 - 0.0038 17.2 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.1 GAM25106.1 - 0.008 16.6 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS PF00989.19 GAM25106.1 - 0.013 15.2 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 PAS fold GAF_3 PF13492.1 GAM25106.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 GAF domain Folliculin PF11704.3 GAM25108.1 - 3.4e-39 134.1 0.1 6.4e-39 133.2 0.1 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SH3_9 PF14604.1 GAM25109.1 - 8.1e-18 63.7 0.2 1.8e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 GAM25109.1 - 2.3e-14 53.3 0.0 2.3e-14 53.3 0.0 4.0 3 2 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAM25109.1 - 3.5e-14 51.9 0.1 6.3e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM25109.1 - 6.6e-14 51.1 0.0 1.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAS PF13851.1 GAM25109.1 - 0.0017 17.6 26.3 0.028 13.6 3.1 2.4 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 GAM25109.1 - 0.0021 16.5 13.2 0.13 10.7 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF342) DUF4613 PF15390.1 GAM25109.1 - 0.098 10.8 13.7 0.015 13.5 6.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) hDGE_amylase PF14701.1 GAM25109.1 - 0.14 10.9 7.8 3.1 6.6 3.9 2.1 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme HSA PF07529.8 GAM25109.1 - 0.35 10.6 6.7 1.2 9.0 0.0 4.0 3 1 0 3 3 3 0 HSA Vps5 PF09325.5 GAM25109.1 - 0.65 9.1 23.1 1.5 8.0 9.3 4.1 2 2 1 3 3 3 0 Vps5 C terminal like Uds1 PF15456.1 GAM25109.1 - 1.1 9.3 17.5 0.11 12.4 1.8 2.6 2 0 0 2 2 2 0 Up-regulated During Septation TPR_MLP1_2 PF07926.7 GAM25109.1 - 2.2 8.0 32.0 0.12 12.1 10.3 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein LRR_6 PF13516.1 GAM25110.1 - 1.2e-13 49.5 43.8 0.00053 19.7 0.1 11.8 12 1 0 12 12 12 6 Leucine Rich repeat LRR_1 PF00560.28 GAM25110.1 - 3.1e-05 23.3 28.1 0.44 10.7 0.0 10.1 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_4 PF12799.2 GAM25110.1 - 4.5e-05 22.9 43.2 0.0007 19.1 0.1 8.6 4 3 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM25110.1 - 0.034 13.9 38.5 0.14 11.9 0.4 7.1 3 3 3 6 6 6 0 Leucine rich repeat F-box-like PF12937.2 GAM25110.1 - 0.053 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Alpha_GJ PF03229.8 GAM25110.1 - 0.073 13.4 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J LRR_7 PF13504.1 GAM25110.1 - 1.4 9.4 29.0 7.6 7.2 0.0 9.9 10 1 0 10 10 10 0 Leucine rich repeat WD40 PF00400.27 GAM25111.1 - 4.5e-34 115.1 12.7 1.3e-07 31.1 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 GAM25111.1 - 9.4e-07 28.4 0.3 1.6e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM25111.1 - 2.6e-05 23.7 0.2 5.8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAM25111.1 - 0.00018 21.0 2.3 0.2 11.0 0.0 3.3 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.1 GAM25111.1 - 0.00076 19.2 0.9 0.16 11.7 0.0 3.3 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 GAM25111.1 - 0.055 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Hira PF07569.6 GAM25111.1 - 0.42 9.8 3.1 3.2 6.8 0.1 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split Anoctamin PF04547.7 GAM25112.1 - 2.6e-08 32.9 22.8 6.6e-05 21.7 15.8 3.3 1 1 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.8 GAM25112.1 - 2.9e-08 34.0 0.1 2.9e-08 34.0 0.1 2.3 3 1 0 3 3 3 1 TMC domain DUF221 PF02714.10 GAM25112.1 - 0.27 10.0 32.1 0.056 12.3 15.5 3.2 2 2 0 2 2 2 0 Domain of unknown function DUF221 WD40 PF00400.27 GAM25113.1 - 1.9e-08 33.8 11.4 0.39 10.6 0.0 8.4 7 1 0 7 7 7 2 WD domain, G-beta repeat BBS2_N PF14781.1 GAM25113.1 - 6.6e-05 22.5 1.0 0.14 11.7 0.1 3.4 2 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, N-terminal S-layer PF07752.6 GAM25113.1 - 0.0056 15.9 0.2 0.014 14.5 0.1 1.6 1 0 0 1 1 1 1 S-layer protein DUF1668 PF07893.8 GAM25113.1 - 0.0071 15.5 0.1 2.6 7.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1668) PAN_3 PF08277.7 GAM25113.1 - 0.071 12.7 0.1 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 PAN-like domain COPIIcoated_ERV PF07970.7 GAM25114.1 - 1.6e-51 175.0 1.3 2.5e-51 174.4 0.9 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAM25114.1 - 5.4e-23 80.7 0.1 9.8e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3672 PF12421.3 GAM25114.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III protein DUF4106 PF13388.1 GAM25114.1 - 0.38 9.6 8.4 0.56 9.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Pex14_N PF04695.8 GAM25114.1 - 1.6 8.7 9.5 1.8 8.6 4.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1632 PF07857.7 GAM25115.1 - 1.2e-52 178.7 13.0 1.2e-52 178.7 9.0 2.0 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 GAM25115.1 - 1.7e-09 37.2 22.8 2.7e-09 36.5 5.9 2.8 2 1 1 3 3 3 2 Sugar transport protein DUF606 PF04657.8 GAM25115.1 - 0.0038 17.3 12.3 0.0038 17.3 8.5 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF606 LRR_6 PF13516.1 GAM25116.1 - 2.3e-05 23.9 9.8 1.2 9.4 0.0 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 GAM25116.1 - 0.00029 20.3 12.2 0.11 12.1 0.7 5.1 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM25116.1 - 0.0013 18.4 7.0 31 5.1 0.0 6.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.1 GAM25116.1 - 0.078 12.7 6.8 0.22 11.3 0.2 3.8 4 0 0 4 4 4 0 Leucine rich repeat CAF-1_p150 PF11600.3 GAM25116.1 - 2.2 7.5 12.2 1.4 8.2 5.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal KMP11 PF03037.11 GAM25117.1 - 0.098 13.2 2.2 1.1 9.8 0.4 3.0 3 0 0 3 3 3 0 Kinetoplastid membrane protein 11 Rap_GAP PF02145.10 GAM25118.1 - 4.6e-58 195.7 0.3 7.5e-58 195.0 0.2 1.3 1 0 0 1 1 1 1 Rap/ran-GAP RNA_POL_M_15KD PF02150.11 GAM25119.1 - 1.1e-08 34.5 2.4 1.1e-08 34.5 1.7 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 GAM25119.1 - 3.4e-08 32.9 10.8 4.3e-08 32.6 2.9 3.2 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) DZR PF12773.2 GAM25119.1 - 1.2e-05 24.9 4.6 0.022 14.5 0.1 2.3 2 0 0 2 2 2 2 Double zinc ribbon Terminase_GpA PF05876.7 GAM25119.1 - 0.0053 15.1 2.0 0.0053 15.1 1.4 1.6 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) Nudix_N_2 PF14803.1 GAM25119.1 - 0.0069 16.0 0.8 0.0069 16.0 0.5 3.1 3 1 0 3 3 3 1 Nudix N-terminal CK_II_beta PF01214.13 GAM25119.1 - 0.0096 15.4 5.9 0.95 8.9 0.1 3.1 2 1 1 3 3 3 1 Casein kinase II regulatory subunit zinc_ribbon_5 PF13719.1 GAM25119.1 - 0.036 13.6 9.5 1.5 8.5 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_2 PF13639.1 GAM25119.1 - 0.074 12.8 6.9 0.3 10.9 0.4 2.7 3 0 0 3 3 3 0 Ring finger domain zinc_ribbon_4 PF13717.1 GAM25119.1 - 0.13 12.0 11.3 1.3 8.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-C4_Topoisom PF01396.14 GAM25119.1 - 0.17 11.4 5.9 0.56 9.7 0.7 2.8 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Opy2 PF09463.5 GAM25119.1 - 0.27 11.3 0.3 0.27 11.3 0.2 3.6 4 0 0 4 4 4 0 Opy2 protein zf-C3HC4_4 PF15227.1 GAM25119.1 - 0.39 10.6 7.8 0.51 10.2 0.5 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.16 GAM25119.1 - 0.44 10.4 9.6 35 4.3 6.7 2.8 1 1 0 1 1 1 0 IBR domain Cys_rich_KTR PF14205.1 GAM25119.1 - 0.49 9.8 14.5 0.45 10.0 0.7 3.4 2 2 1 3 3 3 0 Cysteine-rich KTR zf-RING_3 PF14369.1 GAM25119.1 - 0.65 10.0 11.3 4.2 7.4 0.0 3.6 3 1 0 3 3 3 0 zinc-finger DRP PF06044.7 GAM25119.1 - 0.72 8.7 7.2 0.75 8.7 0.5 2.1 1 1 1 2 2 2 0 Dam-replacing family Trm112p PF03966.11 GAM25119.1 - 0.94 9.8 4.0 10 6.5 1.2 2.7 2 1 0 2 2 2 0 Trm112p-like protein zf-H2C2_2 PF13465.1 GAM25119.1 - 1 9.7 12.9 4.3 7.8 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain DNA_ligase_ZBD PF03119.11 GAM25119.1 - 1.1 9.0 7.4 1.3 8.7 0.7 2.8 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-CHY PF05495.7 GAM25119.1 - 1.5 9.0 9.4 2.2 8.5 0.1 2.6 2 1 0 2 2 2 0 CHY zinc finger PHD PF00628.24 GAM25119.1 - 1.5 8.5 13.3 8 6.2 1.1 3.3 2 2 0 2 2 2 0 PHD-finger HypA PF01155.14 GAM25119.1 - 1.8 8.2 5.2 4.7 6.9 1.5 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 GAM25119.1 - 2 8.3 14.8 0.15 11.9 2.1 3.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF164 PF02591.10 GAM25119.1 - 2.6 7.9 6.9 10 6.0 0.0 3.6 4 0 0 4 4 4 0 Putative zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 GAM25119.1 - 2.7 7.8 11.0 8.1 6.3 0.1 4.0 4 0 0 4 4 4 0 PhnA Zinc-Ribbon C1_4 PF07975.7 GAM25119.1 - 3.5 7.6 10.0 1.3 9.0 0.1 3.1 2 1 1 3 3 3 0 TFIIH C1-like domain NADH-G_4Fe-4S_3 PF10588.4 GAM25119.1 - 3.7 6.8 9.8 2 7.7 0.1 3.2 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region RNHCP PF12647.2 GAM25119.1 - 4.6 7.1 7.4 0.58 10.0 0.1 2.5 2 1 0 3 3 3 0 RNHCP domain zf-ribbon_3 PF13248.1 GAM25119.1 - 5.1 6.4 14.9 3.2 7.0 0.4 3.7 3 1 1 4 4 4 0 zinc-ribbon domain zf-LITAF-like PF10601.4 GAM25119.1 - 5.5 6.9 12.0 7.7 6.4 0.2 3.8 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.1 GAM25119.1 - 5.5 6.6 12.0 7 6.2 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-Mss51 PF13824.1 GAM25119.1 - 6.3 6.7 8.9 12 5.8 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C3HC4_2 PF13923.1 GAM25119.1 - 6.5 6.8 9.0 1.4 9.0 0.3 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.7 GAM25119.1 - 9.1 6.1 9.4 2.8 7.8 0.2 2.9 2 2 0 2 2 2 0 zinc-ribbons RdRP PF05183.7 GAM25120.1 - 1.4e-135 453.2 0.0 2.3e-135 452.5 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase ResIII PF04851.10 GAM25120.1 - 1.1e-16 61.2 0.1 2e-15 57.1 0.1 3.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM25120.1 - 1.4e-16 60.4 1.5 4e-16 58.9 0.3 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM25120.1 - 1.3e-15 57.0 0.2 3.6e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TIP49 PF06068.8 GAM25121.1 - 3.7e-177 588.9 8.0 4.7e-177 588.6 5.5 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAM25121.1 - 1.6e-08 34.7 3.6 2.9e-05 24.2 0.1 3.1 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM25121.1 - 1e-07 31.2 2.2 0.00026 20.1 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 GAM25121.1 - 1.7e-06 27.1 0.3 3.5e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 GAM25121.1 - 3.3e-06 27.2 1.7 0.041 14.0 0.0 2.7 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 GAM25121.1 - 9.3e-06 25.7 0.0 7.3e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAM25121.1 - 4.7e-05 23.1 1.0 0.038 13.7 0.1 3.0 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAM25121.1 - 5e-05 22.8 0.2 0.044 13.2 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 GAM25121.1 - 0.00069 18.8 1.1 0.031 13.4 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAM25121.1 - 0.00077 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM25121.1 - 0.0044 16.1 0.4 0.0079 15.3 0.2 1.5 1 0 0 1 1 1 1 KaiC Zeta_toxin PF06414.7 GAM25121.1 - 0.0057 15.7 0.2 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin PIF1 PF05970.9 GAM25121.1 - 0.0077 15.2 1.3 0.42 9.5 0.2 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 GAM25121.1 - 0.009 15.0 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 GAM25121.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 GAM25121.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 GAM25121.1 - 0.016 15.5 0.7 0.037 14.3 0.5 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM25121.1 - 0.02 14.7 0.7 3 7.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_18 PF13238.1 GAM25121.1 - 0.023 14.9 0.3 0.079 13.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM25121.1 - 0.046 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 GAM25121.1 - 0.092 12.1 0.4 0.19 11.1 0.3 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 GAM25121.1 - 0.1 12.0 0.4 0.4 10.1 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zot PF05707.7 GAM25121.1 - 0.11 12.0 0.1 5.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) RVT_1 PF00078.22 GAM25122.1 - 3.9e-33 114.6 0.0 5.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RAG1 PF12940.2 GAM25123.1 - 0.0012 17.3 0.1 0.0016 16.9 0.0 1.1 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1) Nup35_RRM_2 PF14605.1 GAM25124.1 - 0.052 13.3 0.2 4 7.2 0.0 2.2 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif Pox_F17 PF04767.7 GAM25124.1 - 3.2 8.0 8.6 0.37 11.0 2.4 1.8 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein MBOAT_2 PF13813.1 GAM25125.1 - 0.022 14.8 0.9 0.029 14.4 0.6 1.2 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Methyltransf_31 PF13847.1 GAM25126.1 - 8.4e-09 35.1 0.1 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM25126.1 - 9.1e-09 35.2 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM25126.1 - 5.8e-08 33.3 0.0 8.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM25126.1 - 2.1e-07 30.5 0.0 3.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 GAM25126.1 - 2.6e-07 31.0 0.0 4.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM25126.1 - 2.8e-07 30.9 0.1 5.9e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM25126.1 - 6.1e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM25126.1 - 0.0086 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 GAM25126.1 - 0.015 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Beach PF02138.13 GAM25127.1 - 6.4e-113 376.6 0.8 6.4e-113 376.6 0.6 2.7 3 0 0 3 3 3 1 Beige/BEACH domain WD40 PF00400.27 GAM25127.1 - 2e-20 71.8 13.9 4e-05 23.3 0.1 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat PH_BEACH PF14844.1 GAM25127.1 - 1.1e-12 47.7 0.7 1.3e-11 44.2 0.0 3.3 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH PAT1 PF09770.4 GAM25128.1 - 1.4 7.0 37.9 1.6 6.8 26.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RhoGEF PF00621.15 GAM25129.1 - 4.5e-24 85.3 5.6 1.8e-20 73.5 0.7 3.0 2 1 1 3 3 3 2 RhoGEF domain PH PF00169.24 GAM25129.1 - 6.3e-07 29.5 2.1 6.4e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 PH domain IQ PF00612.22 GAM25129.1 - 5.3e-06 25.6 0.1 1.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_10 PF15411.1 GAM25129.1 - 0.0031 17.6 0.1 0.019 15.1 0.0 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2_4 PF13894.1 GAM25129.1 - 0.042 14.1 0.1 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Ca_chan_IQ PF08763.6 GAM25129.1 - 0.11 11.7 0.5 0.26 10.5 0.3 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain GDPD PF03009.12 GAM25130.1 - 7.3e-49 166.5 0.0 1.3e-48 165.7 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family ThaI PF15514.1 GAM25130.1 - 0.078 12.2 0.1 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease ThaI CBM_20 PF00686.14 GAM25131.1 - 1.2e-13 50.4 0.1 1.2e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 Starch binding domain HEAT_2 PF13646.1 GAM25132.1 - 1.5e-40 137.3 20.3 2.4e-15 56.5 1.4 3.3 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 GAM25132.1 - 3e-29 98.4 3.7 2.7e-05 24.2 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 GAM25132.1 - 2.4e-11 42.7 6.3 0.11 12.6 0.1 6.2 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 GAM25132.1 - 1.9e-09 37.7 7.1 0.00083 19.7 0.1 3.8 3 1 0 3 3 3 2 HEAT-like repeat Chorismate_bind PF00425.13 GAM25132.1 - 0.096 11.9 0.1 0.74 9.0 0.0 2.1 2 1 0 2 2 2 0 chorismate binding enzyme Arm PF00514.18 GAM25132.1 - 0.12 12.2 0.8 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Actin PF00022.14 GAM25133.1 - 1.5e-138 461.5 0.0 1.6e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 GAM25133.1 - 2.7e-05 22.9 0.0 0.0015 17.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein RCC1 PF00415.13 GAM25134.1 - 1.3e-52 175.7 25.4 6.5e-08 32.6 0.0 14.0 14 0 0 14 14 14 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM25134.1 - 1.8e-28 97.4 48.9 3.5e-06 26.4 0.5 13.6 14 0 0 14 14 14 9 Regulator of chromosome condensation (RCC1) repeat hSac2 PF12456.3 GAM25134.1 - 5.7e-13 48.2 0.3 1.1e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Inositol phosphatase Hira PF07569.6 GAM25134.1 - 0.11 11.6 0.4 0.74 8.9 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split CBM_X PF06204.6 GAM25134.1 - 0.56 9.7 8.6 29 4.2 0.0 5.4 7 0 0 7 7 7 0 Putative carbohydrate binding domain zf-RVT PF13966.1 GAM25135.1 - 0.53 10.6 3.2 0.76 10.1 0.4 2.3 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase SNF2_N PF00176.18 GAM25136.1 - 1.5e-33 115.9 0.0 1.5e-33 115.9 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM25136.1 - 1.3e-07 31.3 0.0 1.3e-07 31.3 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HARP PF07443.8 GAM25136.1 - 0.044 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 HepA-related protein (HARP) DUF4557 PF15101.1 GAM25136.1 - 0.29 10.9 18.7 0.6 9.9 13.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 GAM25136.1 - 2.3 7.2 31.7 0.31 10.0 17.3 2.3 2 0 0 2 2 2 0 Fms-interacting protein DnaJ PF00226.26 GAM25137.1 - 4.5e-29 99.9 2.9 7.8e-29 99.2 2.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAM25137.1 - 8.4e-24 83.2 0.9 3.8e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAM25137.1 - 2.3e-13 49.9 18.9 4.7e-13 48.9 13.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 GAM25137.1 - 0.00097 19.4 7.9 0.0017 18.6 1.7 2.7 2 0 0 2 2 2 1 Cytochrome c3 HypA PF01155.14 GAM25137.1 - 0.0013 18.3 8.1 0.14 11.8 1.6 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 GAM25137.1 - 0.058 13.0 0.4 0.058 13.0 0.3 3.6 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 GAM25137.1 - 0.2 11.9 8.1 0.055 13.7 3.1 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Cytochrome_C7 PF14522.1 GAM25137.1 - 0.35 10.5 13.2 1.8 8.2 9.1 2.2 1 1 0 1 1 1 0 Cytochrome c7 Stc1 PF12898.2 GAM25137.1 - 0.64 10.1 10.8 4.3 7.4 0.3 2.6 1 1 1 2 2 2 0 Stc1 domain Cytochrom_CIII PF02085.11 GAM25137.1 - 0.88 9.7 10.2 0.12 12.4 3.5 2.2 1 1 1 2 2 2 0 Class III cytochrome C family Zn-ribbon_8 PF09723.5 GAM25137.1 - 2.8 7.9 17.6 2.7 7.9 0.4 4.5 1 1 4 5 5 5 0 Zinc ribbon domain Cytochrome_CBB3 PF13442.1 GAM25137.1 - 4.1 7.6 12.3 11 6.2 3.1 3.9 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III WD40 PF00400.27 GAM25138.1 - 3.4e-31 105.9 16.7 7.6e-10 38.2 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAM25138.1 - 2.2e-21 75.5 0.3 6.3e-21 74.0 0.2 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Sigma70_ner PF04546.8 GAM25138.1 - 4.7 6.7 21.1 0.95 9.0 1.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region DEAD PF00270.24 GAM25139.1 - 1.9e-39 134.8 6.7 1.9e-39 134.8 0.2 3.0 2 2 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM25139.1 - 2.8e-19 68.7 0.0 9.4e-19 67.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM25139.1 - 3e-17 61.9 0.4 2.7e-16 58.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 GAM25139.1 - 0.14 12.2 3.2 1.2 9.2 0.4 3.1 2 1 0 2 2 2 0 AAA domain eIF-5_eIF-2B PF01873.12 GAM25140.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Codanin-1_C PF15296.1 GAM25140.1 - 0.09 12.6 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 Codanin-1 C-terminus Pkinase PF00069.20 GAM25141.1 - 5.2e-52 176.5 0.0 6.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25141.1 - 1.2e-36 126.1 0.0 1.7e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM25141.1 - 0.00071 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 GAM25141.1 - 0.15 10.9 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Tubulin PF00091.20 GAM25142.1 - 3.9e-73 245.8 0.0 5.8e-73 245.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM25142.1 - 7.5e-47 158.5 0.0 1.2e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAM25142.1 - 6.7e-07 29.3 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAM25142.1 - 0.0041 16.6 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Metallophos PF00149.23 GAM25143.1 - 3.8e-05 23.1 1.3 0.00012 21.4 0.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 GAM25143.1 - 0.00092 17.8 0.0 0.0015 17.1 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase 7TMR-DISM_7TM PF07695.6 GAM25143.1 - 2.6 7.6 14.1 1.9 8.1 7.4 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF106 PF01956.11 GAM25144.1 - 3.9e-42 143.6 0.3 4.5e-42 143.4 0.2 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 Synaptobrevin PF00957.16 GAM25144.1 - 0.00054 19.5 1.1 0.00099 18.6 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF4569 PF15133.1 GAM25144.1 - 0.0092 15.4 0.4 0.011 15.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4569) DUF3373 PF11853.3 GAM25144.1 - 0.018 13.5 1.2 0.023 13.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Tropomyosin_1 PF12718.2 GAM25144.1 - 0.027 14.3 7.0 0.035 13.9 4.9 1.1 1 0 0 1 1 1 0 Tropomyosin like Wbp11 PF09429.5 GAM25144.1 - 0.031 14.2 6.4 0.046 13.7 4.4 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 FKBP_N PF01346.13 GAM25144.1 - 0.033 14.2 1.2 0.053 13.5 0.5 1.4 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HALZ PF02183.13 GAM25144.1 - 0.089 12.5 0.7 0.089 12.5 0.5 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3774 PF12609.3 GAM25144.1 - 0.094 13.5 0.5 0.14 13.0 0.4 1.3 1 0 0 1 1 1 0 Wound-induced protein FUN14 PF04930.10 GAM25144.1 - 0.1 12.9 0.2 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 FUN14 family UPF0118 PF01594.11 GAM25144.1 - 0.1 11.5 0.1 0.14 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 DivIC PF04977.10 GAM25144.1 - 0.13 11.7 2.9 0.24 10.9 2.0 1.5 1 1 0 1 1 1 0 Septum formation initiator Folate_carrier PF01770.13 GAM25144.1 - 0.17 10.3 0.6 0.23 9.9 0.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF4363 PF14276.1 GAM25144.1 - 0.49 10.1 4.9 0.46 10.1 1.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4363) MutS_V PF00488.16 GAM25145.1 - 1.1e-50 172.2 0.0 2.7e-50 170.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM25145.1 - 5.9e-28 98.0 0.3 1.2e-27 96.9 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 GAM25145.1 - 0.00016 21.7 0.0 0.00055 20.0 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 GAM25145.1 - 0.0076 16.3 0.0 0.029 14.5 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV UPF0079 PF02367.12 GAM25146.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MSC PF09402.5 GAM25146.1 - 0.2 10.3 3.7 0.68 8.5 2.0 1.7 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain PRESAN PF09687.5 GAM25146.1 - 0.38 10.8 5.0 0.61 10.1 3.4 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal RRM_1 PF00076.17 GAM25147.1 - 2.1e-55 184.2 0.3 1.6e-20 72.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25147.1 - 3.3e-42 142.3 0.1 2.6e-14 52.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25147.1 - 1.4e-27 95.2 0.1 3e-11 42.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM25147.1 - 0.00099 18.8 0.2 0.91 9.3 0.0 3.1 3 1 0 3 3 3 2 Limkain b1 RNA_bind PF08675.6 GAM25147.1 - 0.0056 16.6 0.1 6.7 6.7 0.0 2.9 2 1 1 3 3 3 2 RNA binding domain Nup35_RRM_2 PF14605.1 GAM25147.1 - 0.016 14.9 0.0 3.5 7.4 0.0 3.7 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif Pex14_N PF04695.8 GAM25147.1 - 7.6 6.5 9.7 19 5.2 6.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RCC1 PF00415.13 GAM25148.1 - 2.9e-89 293.1 22.6 1.1e-17 63.9 0.1 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM25148.1 - 1.1e-37 126.7 37.0 8.3e-08 31.6 0.0 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Clathrin PF00637.15 GAM25148.1 - 1.5e-05 24.6 5.2 0.015 14.8 0.3 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS GGDEF PF00990.16 GAM25149.1 - 3.8e-32 111.0 0.0 6e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 GGDEF domain Guanylate_cyc PF00211.15 GAM25149.1 - 0.0033 16.7 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FAD_binding_1 PF00667.15 GAM25150.1 - 4.1e-36 124.4 0.2 2e-35 122.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 GAM25150.1 - 1.6e-17 64.0 0.0 3.5e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2034 PF10356.4 GAM25151.1 - 4.9e-17 61.7 4.0 9e-09 34.7 0.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 GAM25151.1 - 8.7e-07 28.7 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease PP2C PF00481.16 GAM25152.1 - 7e-40 137.0 0.0 1.5e-39 135.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C E1_dh PF00676.15 GAM25153.1 - 8.6e-94 313.6 0.1 1.1e-93 313.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 GAM25153.1 - 0.0083 15.0 0.5 0.053 12.4 0.0 2.5 4 0 0 4 4 4 1 1-deoxy-D-xylulose-5-phosphate synthase DUF3066 PF11266.3 GAM25153.1 - 0.056 13.1 0.5 0.13 11.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3066) WD40 PF00400.27 GAM25154.1 - 7.9e-19 66.7 20.0 5.9e-06 25.9 2.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Tom22 PF04281.8 GAM25154.1 - 2.5e-05 23.8 14.7 3.8e-05 23.2 2.4 2.7 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 AF-4 PF05110.8 GAM25154.1 - 0.49 8.1 32.6 0.089 10.6 9.2 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 GAM25154.1 - 1 9.0 21.3 0.56 9.8 6.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein VIT1 PF01988.14 GAM25155.1 - 1.6e-59 200.9 4.4 1.9e-59 200.7 3.0 1.1 1 0 0 1 1 1 1 VIT family DUF4367 PF14285.1 GAM25155.1 - 0.0037 16.6 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4367) TRI12 PF06609.8 GAM25155.1 - 0.024 12.8 1.7 0.036 12.2 1.2 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.7 GAM25155.1 - 0.2 11.5 3.6 7.5 6.4 0.9 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4149 PF13664.1 GAM25155.1 - 1.4 9.0 7.4 4.8 7.2 3.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Cyclin_N PF00134.18 GAM25156.1 - 0.0084 15.6 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain EMP24_GP25L PF01105.19 GAM25157.1 - 4.1e-50 170.0 0.2 5.2e-50 169.6 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2749 PF10907.3 GAM25157.1 - 0.0067 16.2 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2749) RAMP4 PF06624.7 GAM25157.1 - 0.028 13.9 0.0 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF607 PF04678.8 GAM25157.1 - 0.089 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF2516 PF10724.4 GAM25157.1 - 0.092 12.7 0.1 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) DUF3753 PF12575.3 GAM25157.1 - 0.3 10.9 1.5 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) VHP PF02209.14 GAM25158.1 - 4e-10 39.2 0.5 6.3e-10 38.5 0.4 1.3 1 0 0 1 1 1 1 Villin headpiece domain Ribosomal_L33 PF00471.15 GAM25159.1 - 1.3e-14 54.1 0.2 1.5e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 ELMO_CED12 PF04727.8 GAM25160.1 - 2.5e-07 30.4 0.2 6.4e-07 29.0 0.1 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3091 PF11291.3 GAM25160.1 - 0.051 13.5 0.6 0.13 12.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) DUF2634 PF10934.3 GAM25160.1 - 0.082 12.6 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Auxin_repressed PF05564.7 GAM25160.1 - 0.6 10.7 11.2 1.2 9.7 6.8 2.2 1 1 0 1 1 1 0 Dormancy/auxin associated protein ELMO_CED12 PF04727.8 GAM25161.1 - 1.7e-37 128.6 0.2 6e-37 126.7 0.0 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 GAM25161.1 - 3.8e-06 26.7 0.1 4.1e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) SAP PF02037.22 GAM25162.1 - 4.4e-10 38.8 2.0 4.4e-10 38.8 1.4 2.1 2 0 0 2 2 2 1 SAP domain RRM_5 PF13893.1 GAM25162.1 - 3.2e-06 26.9 0.0 6.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM25162.1 - 0.0034 16.9 0.0 0.0098 15.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25162.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.2 GAM25162.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 HeH/LEM domain P34-Arc PF04045.9 GAM25162.1 - 0.21 10.8 5.4 0.44 9.7 3.7 1.5 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc SSP160 PF06933.6 GAM25162.1 - 0.96 7.3 7.0 2 6.3 4.9 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MAPEG PF01124.13 GAM25163.1 - 6.2e-07 29.0 0.0 7.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 MAPEG family zf-C3HC4_3 PF13920.1 GAM25163.1 - 0.2 11.3 7.0 0.4 10.3 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.7 GAM25164.1 - 2.6e-62 206.5 17.6 1.8e-17 63.0 1.5 5.8 3 2 4 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 GAM25164.1 - 6.8e-05 22.7 6.9 4.6 7.2 0.2 5.8 2 1 4 6 6 6 3 Protein of unknown function (DUF1769) SpoVR PF04293.8 GAM25164.1 - 0.029 12.7 0.2 1.5 7.1 0.0 2.7 3 0 0 3 3 3 0 SpoVR like protein 7tm_2 PF00002.19 GAM25166.1 - 0.00012 21.2 0.4 0.00016 20.8 0.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 GAM25166.1 - 0.00054 19.1 0.6 0.0007 18.8 0.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 GAM25166.1 - 0.011 14.6 0.5 0.014 14.2 0.3 1.2 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor DUF1265 PF06887.9 GAM25166.1 - 0.08 12.6 2.4 0.11 12.1 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) DUF4037 PF13228.1 GAM25167.1 - 6.6e-10 39.1 0.0 2.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4037) FNIP PF05725.7 GAM25168.1 - 1.9e-11 43.6 4.8 4.1e-06 26.6 0.3 3.8 2 1 1 3 3 3 3 FNIP Repeat Nop14 PF04147.7 GAM25169.1 - 3.8e-181 604.0 64.7 1.6e-179 598.6 44.9 2.0 1 1 0 1 1 1 1 Nop14-like family A_deaminase PF00962.17 GAM25170.1 - 5.2e-50 170.2 0.0 1.1e-49 169.1 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 GAM25170.1 - 1.9e-13 50.2 0.3 4e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Pkinase_Tyr PF07714.12 GAM25173.1 - 4.5e-60 202.8 0.0 6e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM25173.1 - 4.8e-52 176.6 0.0 7.3e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.17 GAM25173.1 - 4.3e-20 71.5 27.2 2.5e-10 40.2 7.8 2.6 2 0 0 2 2 2 2 LIM domain Kinase-like PF14531.1 GAM25173.1 - 1.3e-05 24.3 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM25173.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM25173.1 - 0.0016 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM25173.1 - 0.0038 16.6 0.0 0.068 12.5 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 GAM25173.1 - 0.097 12.2 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF605 PF04652.11 GAM25173.1 - 2.5 7.3 15.5 3.5 6.9 10.8 1.1 1 0 0 1 1 1 0 Vta1 like Sulfotransfer_2 PF03567.9 GAM25174.1 - 6.1e-13 49.0 0.4 6.1e-13 49.0 0.3 1.8 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM25174.1 - 7.6e-06 24.8 0.6 9.8e-05 21.1 0.1 2.5 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase DUF1744 PF08490.7 GAM25175.1 - 4.9e-97 325.0 0.0 9e-97 324.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 GAM25175.1 - 5.2e-62 209.5 5.1 1.1e-61 208.5 3.5 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 GAM25175.1 - 7.6e-23 81.0 1.0 3.4e-21 75.5 0.7 2.7 2 1 0 2 2 2 1 DNA polymerase family B Mob1_phocein PF03637.12 GAM25176.1 - 2.1e-45 154.5 0.2 2.5e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family FNIP PF05725.7 GAM25177.1 - 3.1e-23 81.4 1.2 1.2e-09 37.9 0.1 3.4 2 1 1 3 3 3 3 FNIP Repeat LRR_5 PF13306.1 GAM25177.1 - 0.024 14.3 0.0 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) DUF1162 PF06650.7 GAM25178.1 - 9.3e-43 146.4 9.1 6.8e-40 137.0 0.6 4.4 3 2 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM25179.1 - 2.3e-42 143.2 1.1 7.6e-42 141.5 0.7 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ribosomal_L13e PF01294.13 GAM25180.1 - 1.2e-63 213.8 7.9 1.7e-63 213.3 5.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e BRCT PF00533.21 GAM25181.1 - 1e-14 54.4 5.5 3.7e-08 33.4 0.2 2.9 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM25181.1 - 3.5e-05 23.5 0.3 0.15 11.9 0.0 3.2 2 2 0 2 2 2 2 twin BRCT domain LIM PF00412.17 GAM25182.1 - 1e-07 31.9 6.4 2e-07 30.9 4.4 1.5 1 0 0 1 1 1 1 LIM domain Y_phosphatase2 PF03162.8 GAM25183.1 - 1.9e-62 209.4 0.0 2.2e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAM25183.1 - 3.6e-07 30.5 0.0 4.6e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 GAM25183.1 - 4.9e-05 22.9 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM25183.1 - 0.0015 17.9 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 GAM25183.1 - 0.074 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain FNIP PF05725.7 GAM25184.1 - 3.5e-48 161.3 11.5 6.4e-10 38.8 0.1 5.4 2 1 3 6 6 6 6 FNIP Repeat N6_N4_Mtase PF01555.13 GAM25185.1 - 1.9e-05 24.2 0.2 0.00035 20.1 0.0 2.6 2 1 0 2 2 2 1 DNA methylase Methyltransf_26 PF13659.1 GAM25185.1 - 0.0063 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM25185.1 - 0.024 15.2 0.0 0.97 10.0 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain LptE PF04390.7 GAM25185.1 - 0.68 9.6 6.5 1.3 8.7 4.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly DUF4592 PF15262.1 GAM25185.1 - 1.9 9.0 6.6 0.082 13.4 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) SSP160 PF06933.6 GAM25185.1 - 2.9 5.7 13.9 4.1 5.2 9.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 EF-hand_1 PF00036.27 GAM25186.1 - 1.7e-16 58.1 5.7 1.1e-05 24.3 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 GAM25186.1 - 4.8e-15 55.4 2.7 9.2e-09 35.3 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM25186.1 - 2.3e-14 51.9 4.3 0.0005 19.7 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 GAM25186.1 - 8.7e-14 50.8 6.5 1e-05 25.0 0.3 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM25186.1 - 7.6e-12 44.0 10.5 9.1e-05 21.6 0.1 3.6 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 GAM25186.1 - 2.2e-06 27.6 0.2 0.0042 17.0 0.0 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 GAM25186.1 - 8.4e-06 25.6 0.5 0.0036 17.1 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 GAM25186.1 - 6.8e-05 22.5 0.9 0.003 17.2 0.0 2.7 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 GAM25186.1 - 9e-05 22.0 1.4 0.92 9.2 0.0 3.7 3 1 1 4 4 4 2 EF hand YadA_stalk PF05662.9 GAM25186.1 - 0.054 13.2 1.2 0.13 12.0 0.8 1.7 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin VCBS PF13517.1 GAM25186.1 - 0.24 11.8 2.4 0.9 9.9 0.0 2.3 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.13 GAM25186.1 - 9 6.2 9.7 11 5.9 1.2 2.6 2 0 0 2 2 2 0 Dockerin type I repeat AICARFT_IMPCHas PF01808.13 GAM25187.1 - 1.9e-68 230.8 0.0 2.6e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme DUF2930 PF11152.3 GAM25187.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2930) DRTGG PF07085.7 GAM25187.1 - 0.072 12.6 0.1 0.4 10.3 0.0 2.2 3 0 0 3 3 3 0 DRTGG domain MGS PF02142.17 GAM25188.1 - 1.3e-25 89.1 0.0 1.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 MGS-like domain TIG PF01833.19 GAM25189.1 - 2.7e-06 27.2 2.5 2.7e-06 27.2 1.7 5.1 5 1 0 5 5 5 2 IPT/TIG domain EGF_2 PF07974.8 GAM25189.1 - 0.00094 19.2 13.6 0.0031 17.6 9.5 1.9 1 0 0 1 1 1 1 EGF-like domain DUF4564 PF15169.1 GAM25190.1 - 2.7e-46 157.6 0.0 3.1e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) MFS_1 PF07690.11 GAM25191.1 - 4.9e-20 71.5 36.0 4.9e-20 71.5 25.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.2 GAM25192.1 - 3e-38 131.7 29.0 4.4e-38 131.1 20.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.19 GAM25192.1 - 1.8e-32 112.2 22.3 2.4e-29 102.0 12.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAM25192.1 - 6.2e-30 104.2 0.0 1.1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM25192.1 - 8e-17 62.1 6.4 7.7e-10 39.1 0.0 3.7 3 1 1 4 4 4 2 AAA domain ABC2_membrane_2 PF12679.2 GAM25192.1 - 1.9e-11 43.3 12.8 3e-11 42.7 8.9 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3533 PF12051.3 GAM25192.1 - 1.8e-06 26.9 0.0 1.8e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) AAA_15 PF13175.1 GAM25192.1 - 3.8e-06 26.1 0.1 0.014 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 GAM25192.1 - 0.0013 18.2 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain SMC_N PF02463.14 GAM25192.1 - 0.0034 16.6 0.2 0.48 9.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 GAM25192.1 - 0.0099 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 GAM25192.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 GAM25192.1 - 0.017 15.1 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 GAM25192.1 - 0.018 14.7 0.1 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM25192.1 - 0.024 14.8 0.2 0.09 12.9 0.1 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 GAM25192.1 - 0.035 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM25192.1 - 0.042 13.2 0.3 0.18 11.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM25192.1 - 0.052 13.6 0.2 0.25 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM25192.1 - 0.1 12.1 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM25192.1 - 0.12 13.1 0.0 0.3 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 GAM25192.1 - 0.18 12.0 0.6 0.41 10.9 0.4 1.5 1 0 0 1 1 1 0 AAA domain CcmB PF03379.8 GAM25192.1 - 1 8.4 16.3 0.025 13.8 6.5 1.7 2 0 0 2 2 2 0 CcmB protein GATA PF00320.22 GAM25193.1 - 1.9e-15 55.8 4.0 5.5e-15 54.4 2.8 1.8 1 0 0 1 1 1 1 GATA zinc finger Methyltransf_16 PF10294.4 GAM25194.1 - 3.2e-12 46.2 0.0 4.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase YfhD PF14151.1 GAM25194.1 - 0.16 12.0 1.7 0.32 11.1 1.2 1.4 1 0 0 1 1 1 0 YfhD-like protein HECT PF00632.20 GAM25195.1 - 7.3e-65 219.1 0.1 7.3e-65 219.1 0.1 2.5 4 0 0 4 4 4 1 HECT-domain (ubiquitin-transferase) PH PF00169.24 GAM25195.1 - 1.6e-19 70.0 0.5 5.5e-19 68.2 0.4 2.0 1 0 0 1 1 1 1 PH domain SPRY PF00622.23 GAM25195.1 - 3.4e-17 62.6 0.2 8.6e-17 61.3 0.2 1.7 1 0 0 1 1 1 1 SPRY domain PH_9 PF15410.1 GAM25195.1 - 1.5e-08 34.8 0.4 1.5e-08 34.8 0.3 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 GAM25195.1 - 0.015 15.5 0.3 0.051 13.8 0.2 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PSD2 PF07624.6 GAM25195.1 - 0.032 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) DUF775 PF05603.7 GAM25198.1 - 1.3e-17 63.9 2.7 1.7e-17 63.5 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SWIM PF04434.12 GAM25201.1 - 0.042 13.3 0.1 0.042 13.3 0.1 2.2 2 0 0 2 2 2 0 SWIM zinc finger MRC1 PF09444.5 GAM25201.1 - 0.73 10.1 7.5 2.5 8.4 0.6 2.2 1 1 1 2 2 2 0 MRC1-like domain IBB PF01749.15 GAM25201.1 - 2.6 8.2 7.8 1.1 9.4 3.0 2.2 2 0 0 2 2 2 0 Importin beta binding domain AAA_35 PF14516.1 GAM25207.1 - 0.01 14.4 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 GAM25207.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.7 GAM25210.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.1 GAM25210.1 - 0.094 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF1191 PF06697.7 GAM25212.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) BRCT PF00533.21 GAM25213.1 - 1.1e-05 25.4 4.1 2.3e-05 24.4 0.2 3.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain FNIP PF05725.7 GAM25217.1 - 1.5e-33 114.4 8.5 4.3e-07 29.7 0.3 10.6 5 2 4 11 11 11 11 FNIP Repeat TruB_N PF01509.13 GAM25218.1 - 7.3e-36 123.5 0.0 1.2e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) FNIP PF05725.7 GAM25220.1 - 3.7e-26 90.8 0.3 5.4e-05 23.0 0.0 8.4 4 1 8 12 12 12 9 FNIP Repeat LRR_8 PF13855.1 GAM25220.1 - 0.02 14.6 0.2 0.13 11.9 0.0 2.5 2 0 0 2 2 2 0 Leucine rich repeat DUF3430 PF11912.3 GAM25223.1 - 8.4e-10 38.8 5.6 1e-09 38.5 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Kelch_6 PF13964.1 GAM25224.1 - 0.0034 17.5 2.5 7.3 6.9 0.0 3.8 4 0 0 4 4 4 2 Kelch motif DUF4547 PF15080.1 GAM25224.1 - 0.0043 16.5 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4547) Kelch_1 PF01344.20 GAM25224.1 - 0.0049 16.3 10.4 7.8 6.1 0.1 5.1 5 1 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM25224.1 - 0.051 13.7 0.7 9.7 6.4 0.0 3.0 3 0 0 3 3 3 0 Galactose oxidase, central domain PH_7 PF15408.1 GAM25224.1 - 0.12 12.2 0.1 0.51 10.2 0.0 2.1 2 1 1 3 3 3 0 Pleckstrin homology domain Kelch_4 PF13418.1 GAM25224.1 - 0.92 9.3 7.4 3.3 7.5 0.1 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain AAA PF00004.24 GAM25225.1 - 3.7e-46 156.5 0.1 2.6e-42 144.1 0.0 3.4 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 GAM25225.1 - 2.9e-17 62.3 0.7 8.3e-17 60.8 0.5 1.8 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 GAM25225.1 - 2.6e-06 27.5 10.0 4.8e-05 23.4 0.1 4.4 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.9 GAM25225.1 - 3.4e-05 23.8 0.2 0.00013 21.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM25225.1 - 3.9e-05 23.7 0.2 0.00057 19.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 GAM25225.1 - 8.8e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 GAM25225.1 - 0.00095 19.0 0.1 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM25225.1 - 0.0029 17.8 2.3 0.035 14.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAM25225.1 - 0.0073 17.1 0.5 0.04 14.7 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 GAM25225.1 - 0.0074 16.0 0.1 0.071 12.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 GAM25225.1 - 0.014 15.5 0.0 0.044 13.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 GAM25225.1 - 0.024 14.3 0.0 0.086 12.4 0.0 2.1 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 GAM25225.1 - 0.026 13.6 0.1 0.075 12.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAM25225.1 - 0.033 13.9 0.0 0.089 12.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 GAM25225.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.6 4 1 0 4 4 3 0 ABC transporter Hydrolase_3 PF08282.7 GAM25226.1 - 1e-57 195.6 0.1 1.1e-57 195.4 0.1 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 GAM25226.1 - 1.3e-15 57.4 0.2 1.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 GAM25226.1 - 1e-07 32.5 0.6 0.18 12.1 0.1 2.9 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 GAM25226.1 - 1.7e-06 27.1 0.1 0.02 13.8 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase HAD PF12710.2 GAM25226.1 - 2.5e-06 27.8 0.0 9.9e-05 22.5 0.0 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 GAM25226.1 - 0.014 15.6 0.1 8.9 6.5 0.0 2.7 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DDE_Tnp_4 PF13359.1 GAM25228.1 - 1.5e-17 63.6 0.0 1.8e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM25228.1 - 3.4e-08 33.3 0.1 1.2e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 Transposase DDE domain PHD PF00628.24 GAM25229.1 - 2.4e-23 81.5 38.5 2.7e-11 42.9 5.8 3.7 3 0 0 3 3 3 3 PHD-finger Prok-RING_1 PF14446.1 GAM25229.1 - 1.9e-07 30.7 14.6 0.002 17.8 1.8 3.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 Myb_DNA-binding PF00249.26 GAM25229.1 - 0.0001 22.2 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain EVE PF01878.13 GAM25229.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 EVE domain PHD_2 PF13831.1 GAM25229.1 - 0.015 14.6 25.4 0.04 13.2 1.9 4.7 4 0 0 4 4 4 0 PHD-finger C1_1 PF00130.17 GAM25229.1 - 0.019 14.7 0.8 0.019 14.7 0.5 4.1 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-bind_6 PF13921.1 GAM25229.1 - 0.019 15.0 1.3 0.048 13.7 0.1 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain CBM_20 PF00686.14 GAM25230.1 - 3.9e-19 68.0 0.8 8.4e-19 66.9 0.5 1.5 1 0 0 1 1 1 1 Starch binding domain CBM_48 PF02922.13 GAM25230.1 - 0.09 12.8 0.3 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Pro_isomerase PF00160.16 GAM25232.1 - 3.8e-48 163.6 1.4 7.6e-48 162.6 0.2 2.1 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 GAM25232.1 - 3.5e-06 26.6 1.1 0.0021 17.8 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat Kelch_4 PF13418.1 GAM25233.1 - 6.6e-43 144.2 18.6 6.5e-10 38.6 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM25233.1 - 1.4e-36 123.8 7.3 3.4e-06 26.8 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM25233.1 - 3.2e-35 118.8 13.2 4.4e-08 32.9 0.0 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 GAM25233.1 - 2e-32 110.5 13.6 7.3e-09 35.5 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25233.1 - 1.9e-30 104.1 20.0 1.4e-05 24.5 0.0 7.1 6 1 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM25233.1 - 1.2e-23 81.9 12.8 4.4e-06 26.2 0.2 7.2 7 0 0 7 7 7 5 Kelch motif F-box-like PF12937.2 GAM25233.1 - 8.7e-09 34.9 0.1 1.7e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM25233.1 - 2e-05 24.0 0.5 4e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain Complex1_LYR PF05347.10 GAM25237.1 - 9.2e-14 50.9 0.2 1.5e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM25237.1 - 1.4e-12 47.6 0.4 1.4e-12 47.6 0.2 1.5 2 0 0 2 2 2 1 Complex1_LYR-like DUF4476 PF14771.1 GAM25237.1 - 0.063 13.3 0.7 0.13 12.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) SIM_C PF06621.7 GAM25237.1 - 0.13 11.7 0.2 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Single-minded protein C-terminus AA_permease_2 PF13520.1 GAM25238.1 - 9.3e-44 149.6 47.1 1.3e-43 149.1 32.5 1.3 1 1 0 1 1 1 1 Amino acid permease CLN3 PF02487.12 GAM25239.1 - 1.2e-48 165.9 10.8 1.2e-48 165.9 7.5 2.1 1 1 1 2 2 2 2 CLN3 protein Baculo_p74 PF04583.7 GAM25239.1 - 0.049 12.8 0.4 0.08 12.1 0.3 1.3 1 0 0 1 1 1 0 Baculoviridae p74 conserved region S-AdoMet_synt_C PF02773.11 GAM25240.1 - 1.6e-71 238.4 0.1 3e-71 237.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 GAM25240.1 - 1.2e-49 167.2 0.0 2.2e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 GAM25240.1 - 6.6e-44 148.2 0.6 1.3e-43 147.3 0.4 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 GAM25240.1 - 0.031 13.3 0.0 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Amidinotransferase F-box PF00646.28 GAM25241.1 - 0.0027 17.3 0.1 0.0089 15.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM25241.1 - 0.022 14.4 0.4 0.069 12.8 0.3 1.8 1 0 0 1 1 1 0 F-box-like AIP3 PF03915.8 GAM25242.1 - 0.098 11.5 0.6 0.13 11.1 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Bin3 PF06859.7 GAM25243.1 - 7e-39 132.2 0.1 1.5e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_11 PF08241.7 GAM25243.1 - 1.1e-10 41.8 0.0 4.4e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 GAM25243.1 - 7e-10 39.4 0.0 1.7e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM25243.1 - 1.8e-09 37.9 5.4 0.0002 21.7 0.0 3.7 4 1 0 4 4 4 2 Methyltransferase domain Methyltransf_23 PF13489.1 GAM25243.1 - 2.2e-09 37.2 0.0 1.7e-08 34.3 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM25243.1 - 6.6e-08 32.2 1.5 0.00053 19.6 0.1 2.6 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.9 GAM25243.1 - 3.5e-06 26.5 0.0 0.0013 18.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM25243.1 - 0.00013 22.2 0.0 0.061 13.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM25243.1 - 0.0003 20.8 0.0 0.00081 19.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM25243.1 - 0.0069 15.5 4.7 0.037 13.1 0.0 3.4 3 1 1 4 4 4 1 Ribosomal protein L11 methyltransferase (PrmA) SR-25 PF10500.4 GAM25243.1 - 0.0091 15.4 13.4 0.0091 15.4 9.3 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Methyltransf_9 PF08003.6 GAM25243.1 - 0.018 13.7 0.0 0.046 12.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) NodS PF05401.6 GAM25243.1 - 0.09 12.1 0.0 4.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 GAM25243.1 - 0.091 11.7 3.1 0.14 11.2 0.0 2.4 2 1 0 3 3 3 0 Putative methyltransferase Tim54 PF11711.3 GAM25243.1 - 2.4 6.6 11.9 1.2 7.6 3.1 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FNIP_N PF14636.1 GAM25243.1 - 9 6.7 24.8 1.3 9.5 8.7 2.3 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Sulfate_transp PF00916.15 GAM25244.1 - 2.8e-60 203.7 16.4 2.8e-60 203.7 11.4 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM25244.1 - 4.8e-30 103.0 5.0 4.8e-30 103.0 3.4 3.6 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM25244.1 - 7e-17 60.9 0.0 1.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 GAM25244.1 - 5.7e-05 23.0 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain GBP PF02263.14 GAM25245.1 - 1.4e-44 152.1 0.1 2.3e-44 151.4 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 GAM25245.1 - 0.00011 22.1 0.1 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM25245.1 - 0.12 12.1 0.8 0.68 9.7 0.0 2.5 3 1 0 3 3 3 0 Dynamin family Nucleoplasmin PF03066.10 GAM25246.1 - 3 7.3 18.6 1.7 8.1 5.0 2.6 3 0 0 3 3 3 0 Nucleoplasmin SLAC1 PF03595.12 GAM25247.1 - 7.6e-29 100.3 38.6 1e-28 100.0 26.7 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel p450 PF00067.17 GAM25248.1 - 4.6e-84 282.5 0.0 5.1e-84 282.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1295 PF06966.7 GAM25249.1 - 1.1e-38 132.8 5.3 1.2e-38 132.7 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 GAM25249.1 - 7.5e-06 25.7 1.7 1.6e-05 24.6 1.2 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 GAM25249.1 - 6.2e-05 23.1 2.2 9.9e-05 22.4 0.1 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 GAM25249.1 - 0.0042 17.1 0.3 0.0042 17.1 0.2 2.6 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF4396 PF14342.1 GAM25249.1 - 0.03 14.4 2.5 0.15 12.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4396) ERG4_ERG24 PF01222.12 GAM25249.1 - 0.082 11.4 4.0 0.2 10.1 2.7 1.6 1 1 1 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Lipase_3 PF01764.20 GAM25250.1 - 5.3e-25 87.6 0.0 6.7e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM25250.1 - 0.055 12.8 0.1 0.4 10.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Usp PF00582.21 GAM25251.1 - 1.6e-19 70.5 0.0 1.9e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family FTHFS PF01268.14 GAM25252.1 - 1.2e-261 868.5 0.0 1.4e-261 868.4 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Endotoxin_N PF03945.9 GAM25255.1 - 1.1e-31 109.9 3.1 1.6e-31 109.4 2.2 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain AA_permease_C PF13906.1 GAM25256.1 - 5.8e-08 32.4 3.3 6.7e-08 32.2 2.3 1.1 1 0 0 1 1 1 1 C-terminus of AA_permease YL1 PF05764.8 GAM25259.1 - 1.6e-05 24.6 15.3 1.9e-05 24.3 10.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 GAM25259.1 - 5.2e-05 21.3 22.1 6.3e-05 21.1 15.3 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 GAM25259.1 - 0.00013 21.3 15.7 0.00013 21.3 10.9 1.1 1 0 0 1 1 1 1 SDA1 CENP-T PF15511.1 GAM25259.1 - 0.00031 20.1 15.3 0.00042 19.6 10.6 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop53 PF07767.6 GAM25259.1 - 0.0015 17.6 8.1 0.002 17.2 5.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF2890 PF11081.3 GAM25259.1 - 0.0021 18.1 3.3 0.0022 18.0 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) HC2 PF07382.6 GAM25259.1 - 0.0043 16.9 10.4 0.0053 16.6 7.2 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 CDC45 PF02724.9 GAM25259.1 - 0.0082 14.2 21.4 0.011 13.8 14.9 1.0 1 0 0 1 1 1 1 CDC45-like protein Utp14 PF04615.8 GAM25259.1 - 0.02 13.1 8.9 0.023 12.9 6.1 1.1 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 GAM25259.1 - 0.041 12.3 17.6 0.045 12.2 12.2 1.1 1 0 0 1 1 1 0 Daxx Family IFT57 PF10498.4 GAM25259.1 - 0.043 12.5 4.8 0.05 12.3 3.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Osteopontin PF00865.13 GAM25259.1 - 0.3 10.2 25.7 0.39 9.8 17.8 1.3 1 0 0 1 1 1 0 Osteopontin RRN3 PF05327.6 GAM25259.1 - 0.58 8.2 14.4 0.72 7.8 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HSP90 PF00183.13 GAM25259.1 - 0.6 8.4 11.4 0.8 8.0 7.9 1.2 1 0 0 1 1 1 0 Hsp90 protein SGT1 PF07093.6 GAM25259.1 - 0.78 8.0 14.1 0.85 7.9 9.8 1.1 1 0 0 1 1 1 0 SGT1 protein Apt1 PF10351.4 GAM25259.1 - 1.1 8.0 7.0 1.3 7.8 4.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2796 PF10986.3 GAM25259.1 - 1.2 9.1 8.1 1.4 8.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) eIF-3c_N PF05470.7 GAM25259.1 - 2.5 6.1 12.4 2.9 5.8 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pox_RNA_Pol_19 PF05320.7 GAM25259.1 - 3.3 7.4 13.8 5.1 6.8 9.6 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CobT PF06213.7 GAM25259.1 - 5.8 5.9 21.2 7.5 5.5 14.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 GAM25259.1 - 8.5 5.3 26.4 11 4.9 18.3 1.1 1 0 0 1 1 1 0 BUD22 Rad60-SLD PF11976.3 GAM25260.1 - 7e-06 25.6 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 GAM25260.1 - 2.7e-05 24.0 0.0 5.2e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 GLUT4 regulating protein TUG YukD PF08817.5 GAM25260.1 - 0.0016 18.9 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.18 GAM25260.1 - 0.004 16.5 0.1 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family RasGEF PF00617.14 GAM25262.1 - 1.1e-42 145.9 0.3 3.4e-42 144.3 0.2 1.9 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.22 GAM25262.1 - 8.5e-12 44.9 0.1 8.5e-12 44.9 0.1 2.7 3 0 0 3 3 3 1 RhoGAP domain RasGEF_N PF00618.15 GAM25262.1 - 4.8e-07 29.8 1.2 1.2e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Mon1 PF03164.9 GAM25264.1 - 4.6e-113 377.9 12.7 5.4e-113 377.7 8.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 CDK2AP PF09806.4 GAM25265.1 - 7.2e-05 23.1 15.2 7.2e-05 23.1 10.6 4.7 5 1 0 5 5 5 1 Cyclin-dependent kinase 2-associated protein TPR_12 PF13424.1 GAM25265.1 - 8.8e-05 22.3 14.3 0.28 11.1 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM25265.1 - 0.38 10.4 10.1 9.2 6.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Kdo PF06293.9 GAM25266.1 - 1e-14 54.0 0.0 1.3e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 GAM25266.1 - 1.6e-12 47.1 0.2 2.5e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAM25266.1 - 2.9e-09 37.0 0.0 0.00047 19.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 GAM25266.1 - 3e-09 36.3 0.1 4.7e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 GAM25266.1 - 1.8e-07 30.7 0.0 2.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family EcKinase PF02958.15 GAM25266.1 - 7.5e-05 22.0 0.1 0.00019 20.6 0.0 1.7 1 1 1 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 GAM25266.1 - 0.0032 17.0 0.1 0.0043 16.6 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 GAM25266.1 - 0.016 14.5 0.1 0.039 13.2 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL AA_permease_2 PF13520.1 GAM25267.1 - 3.6e-60 203.7 35.8 3.6e-60 203.7 24.8 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 GAM25267.1 - 3.1e-48 164.3 40.1 3.1e-48 164.3 27.8 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 GAM25267.1 - 1.3e-21 76.1 8.4 1.3e-21 76.1 5.8 3.9 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.8 GAM25267.1 - 4.7e-05 22.2 13.5 4.7e-05 22.2 9.4 3.1 2 2 0 2 2 2 1 Spore germination protein Auto_anti-p27 PF06677.7 GAM25268.1 - 1.4e-15 56.7 5.2 7.2e-08 32.0 0.4 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) IBR PF01485.16 GAM25268.1 - 0.0098 15.7 1.5 4.7 7.1 0.1 2.8 2 0 0 2 2 2 2 IBR domain Ribosomal_S27e PF01667.12 GAM25268.1 - 0.016 14.7 2.1 0.049 13.1 1.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 Ribosomal_S26e PF01283.14 GAM25268.1 - 0.14 12.3 4.2 0.9 9.7 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein S26e PAT1 PF09770.4 GAM25268.1 - 0.16 10.1 30.9 0.38 8.9 7.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pol_alpha_B_N PF08418.5 GAM25268.1 - 0.42 10.1 24.3 0.4 10.1 9.1 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal PHD PF00628.24 GAM25268.1 - 3.5 7.4 8.7 4.1 7.1 1.3 2.7 2 0 0 2 2 2 0 PHD-finger DUF2387 PF09526.5 GAM25268.1 - 3.5 7.6 22.3 6.8 6.6 2.8 3.2 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) EF-hand_7 PF13499.1 GAM25269.1 - 4.1e-19 68.4 7.5 2.1e-12 46.9 0.4 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM25269.1 - 1.9e-18 64.2 5.1 5.8e-05 22.1 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAM25269.1 - 3.4e-15 54.4 1.2 0.00019 21.0 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM25269.1 - 2.7e-12 46.0 7.2 5.3e-06 25.9 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM25269.1 - 6.7e-12 44.1 4.0 0.003 16.8 0.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.2 GAM25269.1 - 0.0042 16.8 1.6 0.077 12.7 0.1 3.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2968 PF11180.3 GAM25269.1 - 0.0081 15.5 18.9 0.0081 15.5 13.1 5.6 1 1 5 6 6 4 1 Protein of unknown function (DUF2968) IncA PF04156.9 GAM25269.1 - 0.01 15.4 12.4 0.01 15.4 8.6 5.8 2 1 4 6 6 4 0 IncA protein SPARC_Ca_bdg PF10591.4 GAM25269.1 - 0.23 11.4 0.0 0.23 11.4 0.0 6.5 5 2 0 5 5 4 0 Secreted protein acidic and rich in cysteine Ca binding region Filament PF00038.16 GAM25269.1 - 0.24 10.8 91.6 0.46 9.8 16.7 5.0 1 1 3 4 4 4 0 Intermediate filament protein Reo_sigmaC PF04582.7 GAM25269.1 - 0.31 10.1 37.3 2.1 7.4 4.2 4.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein EF-hand_9 PF14658.1 GAM25269.1 - 0.61 10.0 0.0 0.61 10.0 0.0 4.5 6 0 0 6 6 5 0 EF-hand domain GAS PF13851.1 GAM25269.1 - 9 5.4 97.6 0.45 9.6 21.2 6.3 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 GAM25269.1 - 9.1 3.4 112.5 3.7 4.7 53.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) PH PF00169.24 GAM25270.1 - 2.8e-11 43.5 0.0 1.2e-10 41.5 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM25270.1 - 0.054 13.7 0.3 0.054 13.7 0.2 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain TIM21 PF08294.6 GAM25271.1 - 6.6e-08 32.3 0.5 8.1e-08 32.0 0.3 1.2 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 GAM25271.1 - 7.3e-07 28.7 0.0 1.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4604 PF15377.1 GAM25272.1 - 2.8 8.1 42.5 0.016 15.3 17.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) Daxx PF03344.10 GAM25272.1 - 7.3 4.9 31.8 12 4.2 22.0 1.4 1 0 0 1 1 1 0 Daxx Family dCMP_cyt_deam_1 PF00383.17 GAM25273.1 - 3e-17 62.1 0.6 3.6e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 GAM25273.1 - 2.2e-10 40.6 0.1 3.4e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region PH PF00169.24 GAM25274.1 - 5.4e-22 77.9 1.4 1.9e-11 44.0 0.2 3.2 3 1 0 3 3 3 2 PH domain PH_11 PF15413.1 GAM25274.1 - 5e-07 29.9 5.9 0.18 12.0 0.9 4.5 4 1 0 4 4 4 3 Pleckstrin homology domain PH_9 PF15410.1 GAM25274.1 - 0.03 14.4 2.5 0.14 12.3 0.1 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain FNIP PF05725.7 GAM25276.1 - 3.8e-34 116.3 13.9 2.6e-12 46.4 0.1 6.5 5 1 1 6 6 6 5 FNIP Repeat DDE_Tnp_4 PF13359.1 GAM25277.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM25277.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain GSHPx PF00255.14 GAM25278.1 - 6.3e-05 22.3 0.1 0.0001 21.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 GAM25279.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase FNIP PF05725.7 GAM25280.1 - 1.7e-55 184.7 0.5 7.5e-14 51.4 0.0 7.6 5 2 1 7 7 7 7 FNIP Repeat DUF480 PF04337.7 GAM25280.1 - 0.038 13.8 0.1 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF480 Glyco_hydr_30_2 PF14587.1 GAM25281.1 - 3e-16 59.3 3.4 5.6e-16 58.4 2.4 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 GSHPx PF00255.14 GAM25282.1 - 2.8e-21 74.9 0.3 3.6e-21 74.5 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase NCU-G1 PF15065.1 GAM25282.1 - 0.041 12.5 0.0 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 GSHPx PF00255.14 GAM25283.1 - 6.4e-27 93.0 0.2 8.4e-27 92.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Pkinase_Tyr PF07714.12 GAM25284.1 - 6.9e-64 215.4 0.0 1e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM25284.1 - 3.6e-49 167.2 0.0 7.9e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 GAM25284.1 - 6.3e-06 25.3 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM25284.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_1 PF00175.16 GAM25286.1 - 4.5e-29 101.2 0.0 7.4e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 GAM25286.1 - 7.2e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 GAM25286.1 - 3.6e-06 26.9 0.0 9.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Sulfate_transp PF00916.15 GAM25287.1 - 3.4e-65 219.8 7.6 5.4e-65 219.1 5.3 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM25287.1 - 1.3e-33 114.4 2.9 3.9e-33 112.9 2.0 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif DUF3498 PF12004.3 GAM25287.1 - 0.088 11.9 0.8 0.14 11.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) IF-2B PF01008.12 GAM25288.1 - 7.4e-72 241.6 0.1 8.4e-72 241.5 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ERCC4 PF02732.10 GAM25290.1 - 1.4e-23 83.2 0.0 2.5e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF3580 PF12117.3 GAM25290.1 - 0.036 14.0 1.0 0.08 12.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) zf-DHHC PF01529.15 GAM25291.1 - 5.2e-28 97.6 10.1 5.2e-28 97.6 7.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase 60KD_IMP PF02096.15 GAM25291.1 - 0.014 15.1 0.5 0.022 14.4 0.4 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein NTP_transf_2 PF01909.18 GAM25292.1 - 5.1e-08 33.1 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 GAM25292.1 - 3.6e-07 30.0 0.6 1.4e-06 28.1 0.4 2.2 1 1 0 1 1 1 1 Cid1 family poly A polymerase WD40 PF00400.27 GAM25293.1 - 8e-19 66.7 11.6 1.7e-05 24.4 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM25293.1 - 6.7e-05 22.6 0.0 0.32 10.7 0.0 3.5 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 GAM25293.1 - 1.1 9.6 3.9 1.5e+02 2.8 0.1 4.6 4 1 0 4 4 4 0 PQQ-like domain JAB PF01398.16 GAM25294.1 - 7.7e-10 38.5 0.0 7.7e-10 38.5 0.0 2.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAM25294.1 - 8.2e-05 22.1 0.3 0.00051 19.5 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Arrestin_N PF00339.24 GAM25294.1 - 0.69 9.7 11.5 0.068 12.9 4.2 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Asp-B-Hydro_N PF05279.6 GAM25294.1 - 3.3 7.5 9.2 4.4 7.0 6.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Serum_albumin PF00273.15 GAM25295.1 - 0.065 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Serum albumin family RhoGEF PF00621.15 GAM25296.1 - 1.9e-22 80.0 0.1 3.2e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM25296.1 - 0.00028 21.0 0.2 0.00096 19.3 0.1 1.9 2 0 0 2 2 2 1 PH domain DZR PF12773.2 GAM25296.1 - 0.0034 17.1 15.5 0.0092 15.7 10.8 1.8 1 0 0 1 1 1 1 Double zinc ribbon Metallophos PF00149.23 GAM25297.1 - 6.1e-17 61.6 1.4 1e-16 60.9 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 GAM25297.1 - 1e-07 31.9 0.0 2.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 GAM25297.1 - 2.7e-07 29.5 0.1 9.9e-07 27.6 0.0 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAM25297.1 - 8.3e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldedh PF00171.17 GAM25298.1 - 4e-78 262.8 0.0 4.8e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 GAM25298.1 - 0.0041 16.3 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Mago-bind PF09282.5 GAM25301.1 - 5.2e-15 54.6 1.0 5.2e-15 54.6 0.7 1.8 2 0 0 2 2 2 1 Mago binding PH PF00169.24 GAM25302.1 - 0.032 14.4 0.1 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 PH domain DUF3447 PF11929.3 GAM25303.1 - 0.00093 18.9 0.0 0.98 9.2 0.1 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.2 GAM25303.1 - 0.0013 18.9 0.0 0.41 11.0 0.0 3.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) AvrPto PF11592.3 GAM25303.1 - 0.0072 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Central core of the bacterial effector protein AvrPto UPF0197 PF05251.7 GAM25304.1 - 3.1e-16 59.4 5.3 3.3e-16 59.3 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) CAAD PF14159.1 GAM25304.1 - 0.022 14.3 0.5 0.036 13.6 0.1 1.5 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Tetraspannin PF00335.15 GAM25304.1 - 0.073 12.3 4.9 0.082 12.1 3.4 1.0 1 0 0 1 1 1 0 Tetraspanin family TMEM220 PF15071.1 GAM25304.1 - 0.09 13.2 0.0 0.1 13.0 0.0 1.0 1 0 0 1 1 1 0 Transmembrane family 220, helix DUF202 PF02656.10 GAM25304.1 - 1.5 9.0 4.1 1.9 8.7 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PEP_mutase PF13714.1 GAM25305.1 - 8.9e-57 192.0 2.5 1e-56 191.8 1.8 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 GAM25305.1 - 3.8e-18 64.9 1.0 5.6e-18 64.4 0.3 1.5 2 0 0 2 2 2 1 Isocitrate lyase family Peptidase_C48 PF02902.14 GAM25306.1 - 4.9e-11 42.6 2.7 4.9e-11 42.6 1.9 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.14 GAM25307.1 - 2e-08 34.1 0.1 4.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YL1 PF05764.8 GAM25308.1 - 9.2e-09 35.2 7.1 1e-08 35.1 4.9 1.0 1 0 0 1 1 1 1 YL1 nuclear protein TT_ORF2 PF02957.10 GAM25308.1 - 0.081 13.6 3.6 0.13 13.0 2.5 1.3 1 0 0 1 1 1 0 TT viral ORF2 ELM2 PF01448.19 GAM25308.1 - 0.11 13.1 0.9 0.48 11.1 0.0 2.0 1 1 1 2 2 2 0 ELM2 domain Nop14 PF04147.7 GAM25308.1 - 0.12 10.2 9.4 0.12 10.2 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 GAM25308.1 - 0.13 11.2 5.3 0.15 11.0 3.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.1 GAM25308.1 - 0.14 11.7 4.2 0.18 11.4 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop25 PF09805.4 GAM25308.1 - 0.22 11.6 4.4 0.24 11.4 3.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2457 PF10446.4 GAM25308.1 - 0.52 8.9 12.9 0.57 8.8 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_RNA_Pol_19 PF05320.7 GAM25308.1 - 0.54 9.9 5.4 0.71 9.6 3.7 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NOA36 PF06524.7 GAM25308.1 - 1 8.5 6.2 1.1 8.4 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 GAM25308.1 - 1.9 6.8 11.6 2.1 6.7 8.0 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 GAM25308.1 - 4.5 6.4 12.6 5.2 6.2 8.7 1.1 1 0 0 1 1 1 0 SDA1 Sec6 PF06046.8 GAM25309.1 - 1.2e-117 393.4 4.9 1.2e-117 393.4 3.4 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF3629 PF12302.3 GAM25309.1 - 0.037 13.3 0.3 0.037 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3629) OSCP PF00213.13 GAM25309.1 - 1.8 8.4 11.4 0.29 10.9 2.8 3.0 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit FNIP PF05725.7 GAM25310.1 - 4.4e-15 55.3 19.6 5.7e-06 26.1 0.6 6.9 7 1 0 7 7 7 4 FNIP Repeat Arf PF00025.16 GAM25311.1 - 5.9e-66 220.9 0.2 6.7e-66 220.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM25311.1 - 5.4e-16 58.4 0.1 5.9e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM25311.1 - 4e-15 55.5 0.0 4.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAM25311.1 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 GAM25311.1 - 4.3e-11 42.1 2.6 4.6e-09 35.4 0.1 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM25311.1 - 3.3e-09 36.2 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM25311.1 - 2.2e-07 30.8 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 GAM25311.1 - 0.00093 18.8 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 2 NACHT domain ATP_bind_1 PF03029.12 GAM25311.1 - 0.0022 17.6 0.2 0.068 12.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 GAM25311.1 - 0.0024 18.2 0.6 0.0086 16.3 0.4 1.8 1 1 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 GAM25311.1 - 0.0024 17.3 1.2 0.019 14.3 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 GAM25311.1 - 0.0065 15.9 0.7 0.032 13.6 0.2 2.1 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain DUF3920 PF13058.1 GAM25311.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) PduV-EutP PF10662.4 GAM25311.1 - 0.029 13.8 0.2 0.091 12.2 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 GAM25311.1 - 0.035 14.3 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM25311.1 - 0.041 13.7 0.2 0.084 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Vmethyltransf PF01660.12 GAM25311.1 - 0.088 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase AAA_14 PF13173.1 GAM25311.1 - 0.093 12.6 0.8 1.2 9.0 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 GAM25311.1 - 0.14 13.0 1.9 1.3 9.8 1.3 2.3 1 1 1 2 2 2 0 AAA domain cobW PF02492.14 GAM25311.1 - 0.33 10.3 1.6 2 7.7 0.1 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2681 PF10883.3 GAM25312.1 - 0.15 12.2 1.5 0.19 11.9 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) PDR_CDR PF06422.7 GAM25312.1 - 3 7.5 6.6 3.1 7.5 0.1 2.8 1 1 2 3 3 3 0 CDR ABC transporter Pkinase PF00069.20 GAM25313.1 - 1.8e-62 210.8 1.4 2.8e-62 210.2 1.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25313.1 - 8.5e-41 139.7 1.1 1.3e-40 139.1 0.8 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM25313.1 - 0.00037 20.2 0.0 0.052 13.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM25313.1 - 0.00087 18.9 1.7 0.0018 17.9 1.2 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 GAM25313.1 - 0.006 15.6 0.3 0.017 14.2 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM25313.1 - 0.029 13.3 0.0 0.078 11.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 GAM25313.1 - 0.15 11.4 0.5 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Abhydrolase_6 PF12697.2 GAM25314.1 - 1.1e-27 97.4 0.0 1.3e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM25314.1 - 4.7e-10 39.3 0.1 6.1e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 GAM25314.1 - 2.3e-07 30.6 0.2 3.6e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 GAM25314.1 - 1.9e-06 27.5 0.7 0.0036 16.8 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.9 GAM25314.1 - 0.0018 17.5 0.1 0.0029 16.9 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 GAM25314.1 - 0.0077 16.0 0.1 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 GAM25314.1 - 0.0092 16.2 0.0 0.04 14.1 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.20 GAM25314.1 - 0.013 15.1 0.3 0.029 14.0 0.2 1.6 1 1 0 1 1 1 0 Lipase (class 3) DUF1071 PF06378.6 GAM25314.1 - 0.043 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Abhydrolase_3 PF07859.8 GAM25314.1 - 0.058 12.9 1.5 0.14 11.6 1.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 GAM25314.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 GAM25314.1 - 0.12 11.8 1.8 4.8 6.5 1.2 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase MoCF_biosynth PF00994.19 GAM25315.1 - 6.7e-57 190.9 3.6 4.1e-28 97.5 0.1 3.3 3 1 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.12 GAM25315.1 - 8.8e-41 138.9 0.9 1.5e-40 138.2 0.6 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 GAM25315.1 - 4.5e-13 48.9 0.0 9.1e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) GRP PF07172.6 GAM25315.1 - 0.0023 18.3 1.0 0.0023 18.3 0.7 1.8 2 0 0 2 2 2 1 Glycine rich protein family Ligase_CoA PF00549.14 GAM25315.1 - 0.058 12.9 0.7 0.12 11.9 0.5 1.5 1 0 0 1 1 1 0 CoA-ligase Epiglycanin_C PF14654.1 GAM25315.1 - 4.9 7.1 9.2 11 6.1 6.4 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Glyco_hydro_18 PF00704.23 GAM25316.1 - 2.1e-28 99.7 0.6 2.9e-28 99.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PDZ_2 PF13180.1 GAM25317.1 - 1.2e-07 31.4 0.1 3.2e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.19 GAM25317.1 - 0.00074 19.6 0.0 0.0019 18.3 0.0 1.8 1 1 1 2 2 2 1 PDZ domain (Also known as DHR or GLGF) MSA-2c PF12238.3 GAM25317.1 - 0.0078 15.8 5.4 0.013 15.1 3.7 1.3 1 0 0 1 1 1 1 Merozoite surface antigen 2c PRCC PF10253.4 GAM25317.1 - 0.0094 16.6 0.9 0.011 16.4 0.6 1.3 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting GRASP55_65 PF04495.9 GAM25317.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ORC6 PF05460.8 GAM25317.1 - 0.15 11.0 4.3 0.19 10.8 3.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Shisa PF13908.1 GAM25317.1 - 0.29 11.3 4.7 0.43 10.7 3.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pex14_N PF04695.8 GAM25317.1 - 4.1 7.4 11.1 5.4 7.0 7.6 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bromodomain PF00439.20 GAM25318.1 - 1.4e-07 31.3 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain FHA PF00498.21 GAM25318.1 - 0.022 14.8 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 FHA domain Peptidase_M17 PF00883.16 GAM25319.1 - 2.1e-117 391.4 0.1 2.8e-117 391.0 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 GAM25319.1 - 1.9e-18 66.4 0.2 4.6e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain PDZ_2 PF13180.1 GAM25319.1 - 0.015 15.1 0.1 0.044 13.6 0.0 1.8 1 1 0 1 1 1 0 PDZ domain DUF2291 PF10054.4 GAM25319.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) Dec-1 PF04624.9 GAM25319.1 - 0.76 9.4 3.0 1.3 8.6 2.1 1.3 1 0 0 1 1 1 0 Dec-1 repeat LSM PF01423.17 GAM25320.1 - 4.8e-15 54.8 0.7 8.6e-15 54.0 0.5 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM25320.1 - 0.099 12.5 0.5 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Ataxin 2 SM domain DTHCT PF08070.6 GAM25321.1 - 0.052 14.2 2.2 0.12 13.0 1.5 1.5 1 0 0 1 1 1 0 DTHCT (NUC029) region DUF4537 PF15057.1 GAM25324.1 - 0.00084 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TraT PF05818.7 GAM25326.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DDE_1 PF03184.14 GAM25329.1 - 0.0036 16.4 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-L PF13092.1 GAM25329.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 HTH_Tnp_Tc5 PF03221.11 GAM25330.1 - 1.7e-05 24.5 0.2 5.9e-05 22.7 0.1 1.8 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Transglut_core2 PF13369.1 GAM25330.1 - 0.035 13.5 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF3647 PF12363.3 GAM25330.1 - 0.08 13.0 0.1 0.44 10.6 0.0 2.0 1 1 1 2 2 2 0 Phage protein GCR1_C PF12550.3 GAM25331.1 - 0.043 13.6 0.3 0.08 12.8 0.2 1.5 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes OPT PF03169.10 GAM25333.1 - 2.2e-130 436.0 33.4 2.7e-130 435.7 23.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4535 PF15054.1 GAM25333.1 - 0.044 13.1 0.2 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Herpes_UL43 PF05072.8 GAM25333.1 - 0.074 11.7 8.5 1 8.0 2.4 2.7 2 1 0 3 3 3 0 Herpesvirus UL43 protein DUF3093 PF11292.3 GAM25333.1 - 4.7 7.0 8.0 1.6 8.5 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) TIG PF01833.19 GAM25335.1 - 1.3e-11 44.3 28.8 6.3e-07 29.2 1.2 4.4 4 0 0 4 4 4 3 IPT/TIG domain LRR_4 PF12799.2 GAM25335.1 - 8.7e-05 22.0 9.2 0.0002 20.9 1.0 3.8 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) EGF_2 PF07974.8 GAM25335.1 - 0.00037 20.5 10.5 0.00093 19.3 7.3 1.7 1 0 0 1 1 1 1 EGF-like domain SKG6 PF08693.5 GAM25335.1 - 0.0042 16.3 0.2 0.013 14.8 0.2 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_8 PF13855.1 GAM25335.1 - 0.065 12.9 9.0 0.071 12.8 0.2 3.7 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 GAM25335.1 - 0.075 13.1 4.2 7.7 6.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 GAM25335.1 - 0.14 12.3 2.5 36 4.9 0.0 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat Laminin_EGF PF00053.19 GAM25335.1 - 0.17 11.8 5.7 0.59 10.1 3.9 1.9 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) LRR_7 PF13504.1 GAM25335.1 - 0.22 11.8 2.0 1.1e+02 3.7 1.4 3.9 1 1 0 1 1 1 0 Leucine rich repeat EGF PF00008.22 GAM25335.1 - 0.41 10.6 7.6 0.98 9.4 5.3 1.7 1 0 0 1 1 1 0 EGF-like domain SlyX PF04102.7 GAM25336.1 - 0.01 16.1 1.4 0.023 15.0 1.0 1.5 1 0 0 1 1 1 0 SlyX Cpn60_TCP1 PF00118.19 GAM25337.1 - 3.1e-100 336.0 0.1 4e-100 335.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3439 PF11921.3 GAM25338.1 - 0.031 14.0 2.3 0.079 12.7 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM25338.1 - 2.5 7.8 14.8 2.3 7.9 9.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3138 PF11336.3 GAM25338.1 - 3.6 5.6 6.5 6.9 4.7 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Rib_5-P_isom_A PF06026.9 GAM25339.1 - 2.4e-59 199.5 0.1 3.1e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.8 GAM25339.1 - 0.0097 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.17 GAM25339.1 - 0.055 13.1 0.1 1 8.9 0.0 2.2 1 1 0 2 2 2 0 DeoR C terminal sensor domain Ank_2 PF12796.2 GAM25340.1 - 0.0012 19.1 0.3 2.8 8.3 0.0 3.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM25340.1 - 0.079 13.2 5.0 9 6.8 0.0 6.1 8 0 0 8 8 8 0 Ankyrin repeat Ank_4 PF13637.1 GAM25340.1 - 0.18 12.3 5.3 92 3.7 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Arrestin_N PF00339.24 GAM25341.1 - 1.6e-19 70.1 3.1 3.7e-15 56.0 0.0 3.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 GAM25341.1 - 3.3e-18 66.1 1.0 6.6e-15 55.4 0.3 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain FYVE PF01363.16 GAM25341.1 - 8.5e-18 64.0 15.5 1.5e-17 63.1 10.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 GAM25341.1 - 0.044 13.6 9.7 0.1 12.4 6.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4445 PF14574.1 GAM25341.1 - 0.23 9.6 0.0 0.39 8.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) Myosin_head PF00063.16 GAM25342.1 - 8.1e-239 794.2 0.7 1.8e-238 793.1 0.5 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM25342.1 - 6.9e-46 156.0 0.3 1.5e-45 154.9 0.2 1.6 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 GAM25342.1 - 2.9e-18 64.9 0.2 7.9e-18 63.5 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM25342.1 - 1.6e-17 62.7 0.1 4e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM25342.1 - 1.7e-12 46.6 0.0 4.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 GAM25342.1 - 0.0035 17.4 0.0 0.017 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM25342.1 - 0.0046 17.7 0.0 0.092 13.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 GAM25342.1 - 0.0091 15.1 0.9 0.023 13.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 GAM25342.1 - 0.019 15.2 0.0 0.083 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAM25342.1 - 0.032 13.4 0.2 3.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM25342.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 GAM25342.1 - 0.049 13.8 0.4 0.3 11.2 0.0 2.6 3 0 0 3 3 2 0 RNA helicase AAA_19 PF13245.1 GAM25342.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 GAM25342.1 - 0.059 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.4 GAM25342.1 - 0.12 11.0 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 GAM25342.1 - 0.22 11.0 0.1 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FNIP PF05725.7 GAM25343.1 - 4.8e-40 135.2 23.5 1.2e-14 53.9 0.2 5.0 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.7 GAM25345.1 - 2.4e-78 257.8 26.5 3.4e-13 49.3 0.0 7.2 4 1 1 7 7 7 7 FNIP Repeat FNIP PF05725.7 GAM25346.1 - 5.7e-105 343.0 24.3 5.7e-14 51.7 0.3 7.8 2 1 9 11 11 11 11 FNIP Repeat LRR_5 PF13306.1 GAM25346.1 - 7.2e-05 22.5 0.1 2.7 7.7 0.0 3.8 2 1 3 5 5 4 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 GAM25346.1 - 0.041 13.8 0.0 5.2 7.1 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1769) LRR_8 PF13855.1 GAM25346.1 - 0.11 12.3 9.5 3.6 7.4 0.0 4.8 6 0 0 6 6 6 0 Leucine rich repeat zf-CCHH PF10283.4 GAM25347.1 - 1.2e-05 25.0 1.0 3.6e-05 23.4 0.7 1.8 1 1 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif EGF_2 PF07974.8 GAM25348.1 - 5.4e-05 23.2 30.3 0.0096 16.0 7.4 2.7 2 0 0 2 2 2 2 EGF-like domain DUF4448 PF14610.1 GAM25348.1 - 0.0022 17.5 0.1 0.018 14.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) hEGF PF12661.2 GAM25348.1 - 0.012 15.6 13.3 0.99 9.6 4.3 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 GAM25348.1 - 1.4 8.9 15.8 0.39 10.7 4.4 2.8 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.8 GAM25350.1 - 0.015 15.4 28.4 0.24 11.5 7.5 2.6 2 0 0 2 2 2 0 EGF-like domain DUF3377 PF11857.3 GAM25350.1 - 0.036 13.6 0.1 0.085 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ank_5 PF13857.1 GAM25351.1 - 1.1e-21 76.3 1.9 2.3e-12 46.7 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM25351.1 - 9.1e-21 72.5 0.3 4.7e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 GAM25351.1 - 4.8e-20 71.5 1.1 3.7e-14 52.7 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM25351.1 - 6.6e-18 64.8 0.5 1e-17 64.2 0.3 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM25351.1 - 7e-13 47.4 0.3 1.7e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat HMG-CoA_red PF00368.13 GAM25352.1 - 5.7e-172 571.5 1.0 7.3e-172 571.1 0.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PH PF00169.24 GAM25353.1 - 0.00023 21.3 2.1 0.00023 21.2 0.4 2.1 2 1 0 2 2 2 1 PH domain HHH_4 PF14490.1 GAM25353.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Mpv17_PMP22 PF04117.7 GAM25355.1 - 6.2e-18 64.2 3.2 6.2e-18 64.2 2.2 2.6 2 1 1 3 3 3 1 Mpv17 / PMP22 family TauE PF01925.14 GAM25355.1 - 0.0072 15.8 0.6 0.0099 15.3 0.4 1.4 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE YlbE PF14003.1 GAM25355.1 - 0.049 13.7 0.1 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 YlbE-like protein UQ_con PF00179.21 GAM25357.1 - 1.9e-50 169.9 0.0 2.2e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM25357.1 - 3.4e-05 23.6 0.0 4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM25357.1 - 0.00067 19.5 0.2 0.00099 18.9 0.2 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 GAM25357.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain FNIP PF05725.7 GAM25358.1 - 1.5e-64 213.6 29.4 6.8e-11 41.9 0.1 10.9 7 3 2 11 11 11 10 FNIP Repeat DUF1409 PF07197.7 GAM25358.1 - 0.097 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) HALZ PF02183.13 GAM25358.1 - 0.22 11.2 0.8 0.44 10.3 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DNA_pol_E_B PF04042.11 GAM25360.1 - 5.9e-38 130.2 0.2 1.1e-37 129.3 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ARPC4 PF05856.7 GAM25362.1 - 4.7e-75 250.6 6.7 5.2e-75 250.5 4.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Dala_Dala_lig_C PF07478.8 GAM25362.1 - 0.035 13.4 0.2 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus SUI1 PF01253.17 GAM25363.1 - 7.5e-21 73.7 0.7 1.5e-20 72.7 0.5 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dicty_REP PF05086.7 GAM25363.1 - 0.057 11.1 7.5 0.06 11.1 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 GAM25363.1 - 1.6 8.5 27.2 0.45 10.2 16.8 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Presenilin PF01080.12 GAM25363.1 - 2.2 7.0 5.7 2.7 6.7 3.9 1.1 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.11 GAM25364.1 - 1.6e-43 148.9 15.9 4e-43 147.6 11.0 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein Wzy_C PF04932.10 GAM25364.1 - 0.042 13.6 6.9 0.06 13.1 0.6 2.8 3 1 0 3 3 3 0 O-Antigen ligase Pkinase_Tyr PF07714.12 GAM25365.1 - 2.3e-63 213.6 0.0 1e-62 211.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 GAM25365.1 - 1.2e-57 195.0 0.0 3.1e-57 193.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.1 GAM25365.1 - 4.8e-19 67.8 26.6 4.6e-10 39.0 4.8 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 GAM25365.1 - 1.4e-18 66.0 21.5 1.2e-09 37.6 2.3 4.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM25365.1 - 5.3e-15 53.1 13.6 0.12 12.4 0.1 8.1 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 GAM25365.1 - 1.4e-05 24.4 30.2 0.96 9.9 0.0 8.0 8 0 0 8 8 7 3 Leucine rich repeat APH PF01636.18 GAM25365.1 - 5.9e-05 22.9 0.6 0.00038 20.2 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family LRR_6 PF13516.1 GAM25365.1 - 0.00095 19.0 15.7 0.9 9.8 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich repeat Kinase-like PF14531.1 GAM25365.1 - 0.002 17.1 0.0 0.0053 15.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like V_ATPase_I PF01496.14 GAM25365.1 - 0.16 9.8 1.0 0.26 9.1 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF607 PF04678.8 GAM25365.1 - 0.38 10.6 1.9 0.95 9.3 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 LRR_3 PF07725.7 GAM25365.1 - 2.3 8.1 6.5 0.61 9.9 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat zf-CCCH PF00642.19 GAM25366.1 - 7.3e-15 54.2 25.6 0.00023 20.7 0.8 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 GAM25366.1 - 3.8e-09 36.2 4.7 3.8e-09 36.2 3.3 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 GAM25366.1 - 7.4e-08 31.9 3.9 3.2e-07 29.8 2.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM25366.1 - 7e-07 28.8 4.1 7e-07 28.8 2.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCCH_2 PF14608.1 GAM25366.1 - 4.2e-05 23.3 36.2 0.015 15.3 1.0 5.2 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type zf-rbx1 PF12678.2 GAM25366.1 - 0.00077 19.5 4.9 0.0045 17.0 3.4 2.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM25366.1 - 0.0023 17.9 4.9 0.0023 17.9 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM25366.1 - 0.32 10.8 7.5 0.13 12.2 2.0 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cwf_Cwc_15 PF04889.7 GAM25367.1 - 0.22 11.2 13.8 0.017 14.8 6.1 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.8 GAM25367.1 - 0.89 9.1 10.6 0.17 11.5 3.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.1 GAM25367.1 - 3 8.2 10.4 2.3 8.5 3.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dicty_REP PF05086.7 GAM25368.1 - 0.089 10.5 10.7 0.1 10.3 7.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOBP PF15279.1 GAM25368.1 - 0.19 12.0 13.6 0.26 11.6 9.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SLD3 PF08639.5 GAM25368.1 - 0.2 10.2 17.0 0.24 9.9 11.8 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF605 PF04652.11 GAM25368.1 - 0.55 9.5 19.9 0.7 9.2 13.8 1.1 1 0 0 1 1 1 0 Vta1 like CDK5_activator PF03261.10 GAM25368.1 - 1.2 8.3 10.9 1.6 7.9 7.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SOG2 PF10428.4 GAM25368.1 - 1.2 7.6 19.5 1.5 7.4 13.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FAM176 PF14851.1 GAM25368.1 - 2 8.0 16.1 0.059 13.0 4.2 2.2 1 1 1 2 2 2 0 FAM176 family BUD22 PF09073.5 GAM25368.1 - 3 6.8 29.8 4.8 6.1 20.6 1.3 1 1 0 1 1 1 0 BUD22 DUF566 PF04484.7 GAM25368.1 - 3.9 6.9 16.6 5.3 6.4 11.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ndc1_Nup PF09531.5 GAM25368.1 - 4.8 5.4 7.4 5.6 5.2 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.1 GAM25368.1 - 4.9 5.3 15.7 6.3 5.0 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CAF-1_p150 PF11600.3 GAM25368.1 - 6.4 6.0 26.1 5.8 6.2 17.2 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TAF1_subA PF14929.1 GAM25369.1 - 0.049 12.0 0.1 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_17 PF13431.1 GAM25369.1 - 0.13 12.5 0.3 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3675 PF12428.3 GAM25373.1 - 0.021 15.0 0.4 0.04 14.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) UAA PF08449.6 GAM25374.1 - 4.4e-85 285.2 25.9 5.3e-85 284.9 18.0 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 GAM25374.1 - 9.4e-12 44.8 32.8 1.9e-10 40.5 7.9 3.0 2 2 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 GAM25374.1 - 2.3e-05 23.6 3.2 2.3e-05 23.6 2.2 2.3 2 1 1 3 3 3 1 Nucleotide-sugar transporter EamA PF00892.15 GAM25374.1 - 0.00017 21.6 45.9 0.0065 16.5 6.0 4.1 2 2 1 4 4 4 3 EamA-like transporter family UPF0546 PF10639.4 GAM25374.1 - 0.7 9.7 11.7 0.41 10.4 1.6 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 EmrE PF13536.1 GAM25374.1 - 1.2 9.3 32.9 0.079 13.1 8.2 3.0 3 1 0 3 3 3 0 Multidrug resistance efflux transporter Beta_helix PF13229.1 GAM25375.1 - 1.2e-08 34.8 65.2 0.0025 17.5 14.1 4.1 1 1 2 3 3 3 3 Right handed beta helix region HEAT_2 PF13646.1 GAM25376.1 - 0.00018 21.6 0.0 0.008 16.4 0.0 2.6 2 2 0 2 2 2 1 HEAT repeats HEAT PF02985.17 GAM25376.1 - 0.001 18.9 0.0 0.55 10.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 GAM25376.1 - 0.03 14.1 1.2 0.37 10.6 0.1 2.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1902 PF08972.6 GAM25376.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) CBS PF00571.23 GAM25377.1 - 1.7e-29 101.3 2.3 4.1e-14 52.0 0.1 2.1 2 0 0 2 2 2 2 CBS domain PRC PF05239.11 GAM25377.1 - 0.035 13.9 0.0 0.61 9.9 0.0 2.1 2 0 0 2 2 2 0 PRC-barrel domain UBX PF00789.15 GAM25378.1 - 9.8e-12 44.7 0.1 2.9e-11 43.2 0.0 1.8 2 0 0 2 2 1 1 UBX domain Thioredoxin_7 PF13899.1 GAM25378.1 - 2.1e-10 40.4 0.0 4.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 GAM25378.1 - 7.7e-10 38.1 0.1 2e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 UBA-like domain SAPS PF04499.10 GAM25378.1 - 0.018 13.7 3.2 0.024 13.2 2.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ebola_NP PF05505.7 GAM25378.1 - 0.026 12.6 7.0 0.035 12.1 4.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein TFIIA PF03153.8 GAM25378.1 - 0.031 14.1 15.9 0.052 13.4 11.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 GAM25378.1 - 0.041 12.3 17.3 0.059 11.8 12.0 1.1 1 0 0 1 1 1 0 Daxx Family Thioredoxin_2 PF13098.1 GAM25378.1 - 0.049 13.8 0.1 0.2 11.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Tim54 PF11711.3 GAM25378.1 - 0.077 11.5 1.2 0.13 10.7 0.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.6 GAM25378.1 - 0.2 11.1 15.8 0.34 10.3 11.0 1.3 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.11 GAM25378.1 - 0.21 10.5 5.4 0.32 9.9 3.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FLO_LFY PF01698.11 GAM25378.1 - 0.28 9.9 7.9 0.45 9.3 5.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Nha1_C PF08619.5 GAM25378.1 - 0.37 10.0 16.4 0.58 9.3 11.4 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Nucleo_P87 PF07267.6 GAM25378.1 - 0.53 8.9 8.2 0.76 8.3 5.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nop14 PF04147.7 GAM25378.1 - 1.6 6.5 23.2 2.2 6.0 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3449 PF11931.3 GAM25378.1 - 1.6 8.1 6.8 3.2 7.2 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Sigma70_ner PF04546.8 GAM25378.1 - 2.2 7.8 13.9 4.2 6.9 9.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Na_trans_assoc PF06512.8 GAM25378.1 - 2.6 7.9 12.9 1.2 9.0 7.2 1.6 2 0 0 2 2 2 0 Sodium ion transport-associated CENP-B_dimeris PF09026.5 GAM25378.1 - 5.4 7.3 23.4 1.1e+02 3.1 15.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 GAM25378.1 - 5.4 6.7 12.6 14 5.4 8.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal BUD22 PF09073.5 GAM25378.1 - 6.5 5.7 19.5 11 4.9 13.5 1.3 1 0 0 1 1 1 0 BUD22 UPF0560 PF10577.4 GAM25378.1 - 8 4.5 11.5 11 4.0 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FCP1_C PF09309.5 GAM25379.1 - 1.7 7.8 35.1 1 8.6 6.5 3.2 3 0 0 3 3 3 0 FCP1, C-terminal PAT1 PF09770.4 GAM25379.1 - 8.2 4.5 55.3 2.1 6.4 28.7 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PHD PF00628.24 GAM25380.1 - 2.4e-05 23.9 7.9 2.4e-05 23.9 5.4 3.0 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 GAM25380.1 - 0.0094 15.2 5.6 0.0094 15.2 3.9 2.8 1 1 1 2 2 2 1 PHD-finger Diphthamide_syn PF01866.12 GAM25381.1 - 4.6e-64 216.5 0.5 6.2e-34 117.6 0.1 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein COPI_assoc PF08507.5 GAM25382.1 - 1.5e-18 66.8 6.2 1.8e-18 66.5 4.3 1.1 1 0 0 1 1 1 1 COPI associated protein MAGE PF01454.14 GAM25383.1 - 2.6e-30 105.2 0.1 3.6e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 MAGE family SCP2 PF02036.12 GAM25384.1 - 6.1e-52 174.1 2.2 4.8e-26 91.0 0.2 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 GAM25384.1 - 5.7e-13 48.9 0.3 3.7e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal Ribosomal_60s PF00428.14 GAM25384.1 - 0.034 14.5 3.5 0.091 13.1 2.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Y_Y_Y PF07495.8 GAM25385.1 - 0.00051 19.7 8.8 1.7 8.4 0.1 5.3 6 0 0 6 6 6 2 Y_Y_Y domain DUF2012 PF09430.5 GAM25385.1 - 0.0018 18.0 0.2 12 5.7 0.0 3.9 2 1 2 4 4 4 1 Protein of unknown function (DUF2012) WIF PF02019.13 GAM25385.1 - 0.049 13.0 0.2 4.9 6.5 0.0 2.7 2 0 0 2 2 2 0 WIF domain DUF1425 PF07233.7 GAM25385.1 - 0.14 11.7 0.0 0.81 9.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1425) SKG6 PF08693.5 GAM25385.1 - 0.35 10.2 1.9 0.84 9.0 1.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cna_B PF05738.8 GAM25385.1 - 0.96 9.2 7.2 3.7 7.3 0.3 4.3 4 1 1 5 5 5 0 Cna protein B-type domain Big_3_4 PF13754.1 GAM25385.1 - 1.3 9.3 8.5 1.5 9.2 0.2 4.3 3 1 0 3 3 3 0 Bacterial Ig-like domain (group 3) Acetyltransf_1 PF00583.19 GAM25386.1 - 2.6e-18 65.7 0.0 3.5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM25386.1 - 3.6e-10 39.8 0.1 5.4e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM25386.1 - 1.2e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM25386.1 - 1.1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM25386.1 - 0.00016 21.6 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM25386.1 - 0.0019 17.9 0.0 0.0049 16.5 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 GAM25386.1 - 0.0055 16.2 0.0 0.0074 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM25386.1 - 0.043 13.6 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EF-hand_7 PF13499.1 GAM25387.1 - 2.4e-13 49.9 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM25387.1 - 2e-09 36.0 0.0 0.00038 19.5 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 GAM25387.1 - 9.6e-09 34.7 0.1 0.0014 18.1 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM25387.1 - 1.7e-08 33.6 0.0 0.00035 20.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM25387.1 - 1.9e-05 23.8 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.1 GAM25387.1 - 0.041 13.5 0.1 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 EF hand Cu-binding_MopE PF11617.3 GAM25387.1 - 0.23 11.2 1.2 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Protein metal binding site Ribosomal_L14 PF00238.14 GAM25388.1 - 1.2e-29 102.5 0.0 1.3e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e MRP-L46 PF11788.3 GAM25389.1 - 0.00031 21.3 0.8 0.00031 21.3 0.6 2.4 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Na_H_Exchanger PF00999.16 GAM25390.1 - 8.1e-67 225.3 45.5 9.9e-67 225.0 31.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.7 GAM25390.1 - 7.2e-05 22.3 10.3 7.2e-05 22.3 7.1 2.9 3 0 0 3 3 3 1 Predicted Permease Membrane Region Usp PF00582.21 GAM25390.1 - 0.068 13.3 0.0 4.8 7.3 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family RRM_1 PF00076.17 GAM25391.1 - 1.4e-43 146.3 2.5 7.9e-14 51.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25391.1 - 3.2e-26 91.1 0.2 3.6e-08 33.2 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25391.1 - 2.8e-20 71.9 0.4 1.1e-05 25.2 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM25391.1 - 0.00011 22.0 1.2 0.75 9.6 0.2 3.2 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 GAM25391.1 - 0.008 15.9 0.4 6.3 6.6 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 GAM25391.1 - 0.028 14.4 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 RNA binding domain MSP1_C PF07462.6 GAM25391.1 - 0.038 12.4 7.1 0.07 11.5 5.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glutaredoxin PF00462.19 GAM25392.1 - 2.4e-18 65.8 0.0 4.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.10 GAM25392.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DNA_processg_A PF02481.10 GAM25392.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF1134 PF06577.7 GAM25392.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) TPR_1 PF00515.23 GAM25393.1 - 7.6e-13 47.4 6.4 4.5e-05 22.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM25393.1 - 1.3e-11 43.5 2.7 0.00012 21.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM25393.1 - 1.2e-10 40.9 10.5 1.7e-08 33.9 0.9 3.6 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.1 GAM25393.1 - 1.7e-07 31.4 4.5 7e-07 29.5 2.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM25393.1 - 7.2e-07 29.7 0.7 1.8e-05 25.2 0.1 3.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM25393.1 - 1.3e-05 25.0 6.3 0.0012 18.7 0.6 3.4 1 1 3 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.4 GAM25393.1 - 1.8e-05 23.5 1.1 4.2e-05 22.3 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.1 GAM25393.1 - 2.7e-05 23.6 7.9 0.085 12.6 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM25393.1 - 4.3e-05 23.5 5.0 0.00053 20.0 3.3 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 GAM25393.1 - 7.8e-05 22.0 5.9 0.064 12.4 0.4 2.5 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_9 PF13371.1 GAM25393.1 - 0.00042 20.1 0.1 0.0038 17.0 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM25393.1 - 0.0024 18.2 5.0 1.3 9.6 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM25393.1 - 0.005 17.3 0.4 0.42 11.3 0.0 3.1 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM25393.1 - 0.029 14.1 0.9 1.2 9.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM25393.1 - 0.053 13.7 3.8 41 4.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_12 PF13087.1 GAM25393.1 - 0.082 12.2 2.4 0.2 11.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain TPR_10 PF13374.1 GAM25393.1 - 0.14 12.1 0.6 0.81 9.7 0.1 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAM25393.1 - 0.36 10.7 5.6 0.38 10.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NTF2 PF02136.15 GAM25394.1 - 7.4e-14 52.1 0.1 7.4e-14 52.1 0.1 2.8 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 GAM25394.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25394.1 - 0.0018 18.0 0.0 0.0049 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25394.1 - 0.0032 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 GAM25394.1 - 5.2 6.3 48.9 1 8.6 17.6 2.2 2 0 0 2 2 2 0 Vta1 like UFC1 PF08694.6 GAM25395.1 - 2e-88 293.9 0.5 2.3e-88 293.7 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 GAM25395.1 - 0.0037 17.1 0.1 0.008 16.0 0.1 1.7 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.21 GAM25395.1 - 0.017 14.5 0.5 0.05 13.0 0.3 1.8 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Ras PF00071.17 GAM25396.1 - 7.5e-55 184.7 0.0 8.6e-55 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM25396.1 - 1.9e-17 63.8 0.0 2.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM25396.1 - 9.8e-10 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM25396.1 - 3e-05 23.5 0.0 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM25396.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DNA_pol_A PF00476.15 GAM25397.1 - 2.2e-65 220.7 0.1 2.2e-65 220.7 0.1 2.2 2 1 0 2 2 2 1 DNA polymerase family A Symplekin_C PF12295.3 GAM25398.1 - 5.2e-45 153.6 4.9 5.2e-45 153.6 3.4 2.0 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF2368 PF10166.4 GAM25398.1 - 0.053 13.1 0.7 0.13 11.8 0.5 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DUF3453 PF11935.3 GAM25399.1 - 2.7e-28 99.0 1.1 2.7e-28 99.0 0.8 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3453) UPF0118 PF01594.11 GAM25399.1 - 0.12 11.3 0.3 0.2 10.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 PP2C PF00481.16 GAM25400.1 - 1.6e-66 224.3 0.3 2e-66 224.0 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 GAM25400.1 - 6.5e-07 28.9 0.1 1.5e-06 27.7 0.1 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C BRE PF06113.7 GAM25400.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DUF3006 PF11213.3 GAM25400.1 - 0.12 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) PCI PF01399.22 GAM25401.1 - 1.6e-17 63.7 0.0 4.6e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain DSPc PF00782.15 GAM25402.1 - 4.6e-29 100.6 0.0 1.2e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 GAM25402.1 - 2.2e-26 91.3 27.9 3.8e-09 36.1 0.3 5.3 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 GAM25402.1 - 4.1e-26 90.1 34.9 6.5e-08 32.0 0.7 6.5 2 2 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM25402.1 - 4.8e-16 56.3 32.3 0.068 13.2 0.4 11.0 11 0 0 11 11 10 6 Leucine Rich Repeat LRR_7 PF13504.1 GAM25402.1 - 2.1e-10 39.0 28.7 0.5 10.7 0.2 10.6 12 0 0 12 12 10 3 Leucine rich repeat LRR_9 PF14580.1 GAM25402.1 - 1.7e-05 24.4 5.7 0.00015 21.3 0.4 3.1 2 1 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.1 GAM25402.1 - 5e-05 22.9 31.7 0.094 12.8 0.5 9.1 9 1 1 10 10 9 2 Leucine Rich repeat Y_phosphatase PF00102.22 GAM25402.1 - 0.0046 16.3 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAM25402.1 - 0.03 14.3 0.5 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF2015 PF09435.5 GAM25402.1 - 0.053 13.3 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2015) LRR_2 PF07723.8 GAM25402.1 - 0.79 10.3 6.4 13 6.4 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat RRM_5 PF13893.1 GAM25404.1 - 3.4e-40 135.6 1.1 5.4e-12 45.3 0.0 5.1 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25404.1 - 7.3e-36 121.9 0.2 2.5e-09 36.9 0.0 5.2 4 1 1 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM25404.1 - 2.9e-34 116.5 0.0 8.4e-08 31.7 0.0 5.1 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM25404.1 - 0.028 14.2 0.0 6 6.7 0.0 3.6 4 0 0 4 4 4 0 RNA binding motif Ank_2 PF12796.2 GAM25405.1 - 3.8e-31 107.2 9.7 2.3e-09 37.4 0.6 5.3 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25405.1 - 8.2e-22 77.1 9.9 1.7e-05 25.1 0.1 7.4 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM25405.1 - 7e-21 73.7 9.2 0.022 15.0 0.1 8.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM25405.1 - 1.1e-18 65.3 4.4 0.029 14.6 0.0 10.9 6 3 5 11 11 11 3 Ankyrin repeat Ank PF00023.25 GAM25405.1 - 1.2e-16 59.5 9.9 0.039 13.7 0.1 10.0 9 1 1 10 10 10 6 Ankyrin repeat Astro_capsid_p PF12226.3 GAM25405.1 - 0.093 11.9 0.0 0.3 10.3 0.0 1.8 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Rbsn PF11464.3 GAM25405.1 - 0.17 11.4 7.6 49 3.5 0.1 5.2 6 0 0 6 6 6 0 Rabenosyn Rab binding domain DUF1509 PF07420.6 GAM25409.1 - 0.028 13.6 4.8 0.034 13.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) WEMBL PF05701.6 GAM25409.1 - 0.041 12.3 3.5 0.05 12.0 2.4 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light vATP-synt_E PF01991.13 GAM25409.1 - 0.11 11.7 5.3 0.15 11.3 3.7 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.13 GAM25409.1 - 1.3 8.8 8.4 1.8 8.3 5.8 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Med9 PF07544.8 GAM25409.1 - 5.7 6.7 7.8 8.9 6.1 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_C48 PF02902.14 GAM25410.1 - 1.8e-08 34.3 0.2 4.2e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DEAD PF00270.24 GAM25412.1 - 2.1e-46 157.5 0.0 4e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM25412.1 - 9.7e-28 95.8 0.0 2.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM25412.1 - 0.00016 21.5 0.0 0.0039 17.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM25413.1 - 1.3e-40 138.6 0.1 4.3e-40 136.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM25413.1 - 1.8e-21 75.7 0.3 4.8e-21 74.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 GAM25413.1 - 1.7e-20 72.3 0.3 4.3e-20 71.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ELMO_CED12 PF04727.8 GAM25414.1 - 5.6e-41 139.9 0.1 7.5e-41 139.5 0.1 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Kelch_6 PF13964.1 GAM25415.1 - 1.2e-06 28.3 11.1 0.011 15.8 0.0 5.6 5 1 1 6 6 6 1 Kelch motif Kelch_4 PF13418.1 GAM25415.1 - 2.2e-06 27.3 10.1 8.6e-05 22.2 0.1 5.2 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM25415.1 - 0.0022 17.6 3.2 0.047 13.4 0.1 3.5 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 GAM25415.1 - 0.0056 16.8 0.5 0.8 9.9 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain WG_beta_rep PF14903.1 GAM25415.1 - 0.15 12.3 0.5 2 8.8 0.0 2.8 3 0 0 3 3 3 0 WG containing repeat Kelch_1 PF01344.20 GAM25415.1 - 0.16 11.5 0.2 0.16 11.5 0.1 3.9 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 GAM25416.1 - 3e-10 39.8 5.2 0.015 15.4 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM25416.1 - 3.3e-06 26.7 5.5 0.059 13.1 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25416.1 - 9.1e-06 25.7 4.3 0.068 13.3 0.0 5.2 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM25416.1 - 0.00034 20.2 9.7 3.3 7.6 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 GAM25416.1 - 0.00043 19.7 4.0 0.31 10.6 0.1 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 GAM25416.1 - 0.22 11.5 10.7 4.5 7.3 0.2 3.7 3 0 0 3 3 3 0 Kelch motif Kelch_6 PF13964.1 GAM25417.1 - 0.00053 20.0 1.2 0.36 11.0 0.0 3.8 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 GAM25417.1 - 0.002 17.8 0.1 4 7.3 0.0 3.3 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM25417.1 - 0.0033 17.5 0.2 1.8 8.8 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM25417.1 - 0.014 15.1 3.8 5.8 6.7 0.0 3.9 4 2 0 4 4 4 0 Galactose oxidase, central domain Peptidase_S39 PF02122.10 GAM25417.1 - 0.059 12.6 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase S39 Kelch_1 PF01344.20 GAM25417.1 - 0.53 9.8 2.2 36 4.0 0.0 3.3 3 0 0 3 3 3 0 Kelch motif GLE1 PF07817.8 GAM25418.1 - 0.0053 15.7 3.4 0.0072 15.3 2.4 1.3 1 0 0 1 1 1 1 GLE1-like protein DUF848 PF05852.6 GAM25418.1 - 0.014 15.2 2.5 0.019 14.7 0.8 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Baculo_PEP_C PF04513.7 GAM25418.1 - 0.022 14.5 11.3 0.033 13.9 7.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Serine_rich PF08824.5 GAM25418.1 - 0.025 14.3 0.4 0.031 14.0 0.3 1.1 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF1664 PF07889.7 GAM25418.1 - 0.073 12.8 5.0 0.086 12.6 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Mer2 PF09074.5 GAM25418.1 - 0.075 12.9 6.0 0.094 12.6 4.2 1.3 1 0 0 1 1 1 0 Mer2 ApbA_C PF08546.6 GAM25418.1 - 0.083 12.8 0.2 0.18 11.8 0.1 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal MRC1 PF09444.5 GAM25418.1 - 0.094 13.0 6.2 6.1 7.1 0.0 2.3 1 1 1 2 2 2 0 MRC1-like domain FliD_N PF02465.13 GAM25418.1 - 0.11 12.8 1.7 0.16 12.3 0.2 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3461 PF11944.3 GAM25418.1 - 0.16 11.8 6.1 0.05 13.4 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Ssu72 PF04722.8 GAM25418.1 - 0.33 10.2 5.5 0.58 9.4 3.8 1.5 1 1 0 1 1 1 0 Ssu72-like protein DUF3450 PF11932.3 GAM25418.1 - 0.41 9.8 4.1 0.37 10.0 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Glu-tRNAGln PF02686.10 GAM25418.1 - 0.78 9.5 4.0 1.1 9.1 0.5 2.2 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit CENP-H PF05837.7 GAM25418.1 - 2.2 8.4 8.7 0.082 13.0 1.0 2.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Syntaxin_2 PF14523.1 GAM25418.1 - 3.4 7.7 9.5 13 5.8 5.9 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Kelch_6 PF13964.1 GAM25419.1 - 4.2e-05 23.5 3.1 0.09 12.9 0.0 4.7 3 2 1 4 4 4 1 Kelch motif Kelch_4 PF13418.1 GAM25419.1 - 0.00051 19.7 5.3 0.012 15.3 0.1 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25419.1 - 0.01 15.9 1.9 0.18 12.0 0.0 3.0 4 0 0 4 4 4 0 Galactose oxidase, central domain FpoO PF10621.4 GAM25419.1 - 0.058 13.4 0.1 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO GCIP PF13324.1 GAM25420.1 - 0.055 12.6 2.8 0.072 12.3 1.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting UPF0370 PF13980.1 GAM25420.1 - 2 8.3 7.7 0.4 10.5 1.4 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) Kelch_6 PF13964.1 GAM25421.1 - 4.2e-09 36.2 7.0 0.015 15.4 0.1 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM25421.1 - 4.5e-05 23.1 6.8 2.8 7.7 0.2 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25421.1 - 0.027 14.0 6.0 3 7.4 0.1 3.7 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 GAM25421.1 - 0.088 12.7 7.1 1.1 9.2 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 GAM25421.1 - 2.6 8.3 7.5 61 3.9 0.4 4.7 5 2 0 5 5 5 0 Galactose oxidase, central domain Formyl_trans_N PF00551.14 GAM25422.1 - 8.5e-45 152.5 0.1 9.9e-45 152.3 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase Cpn60_TCP1 PF00118.19 GAM25423.1 - 2.5e-152 507.9 0.2 2.8e-152 507.7 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DnaJ PF00226.26 GAM25424.1 - 2.1e-24 84.9 3.2 5.3e-24 83.7 2.2 1.7 1 0 0 1 1 1 1 DnaJ domain Erf4 PF10256.4 GAM25425.1 - 2.2e-07 30.7 0.4 1.5e-05 24.7 0.3 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TB2_DP1_HVA22 PF03134.14 GAM25425.1 - 0.013 15.2 0.6 0.015 14.9 0.4 1.1 1 0 0 1 1 1 0 TB2/DP1, HVA22 family BPD_transp_1 PF00528.17 GAM25425.1 - 0.091 12.2 5.8 0.12 11.9 4.0 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF2207 PF09972.4 GAM25425.1 - 0.097 11.2 1.1 0.096 11.2 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 GAM25425.1 - 0.31 10.7 4.9 0.45 10.2 3.4 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF805 PF05656.9 GAM25425.1 - 0.37 10.6 5.6 0.55 10.0 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3593 PF12159.3 GAM25425.1 - 1.6 8.5 5.3 45 3.9 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) SieB PF14163.1 GAM25425.1 - 2.2 7.8 5.4 5.8 6.4 0.9 2.0 1 1 1 2 2 2 0 Superinfection exclusion protein B tRNA_bind PF01588.15 GAM25426.1 - 5.2e-29 99.9 0.2 1.1e-28 98.8 0.2 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Utp12 PF04003.7 GAM25427.1 - 0.089 12.7 1.8 1.6 8.7 0.1 2.5 1 1 1 2 2 2 0 Dip2/Utp12 Family Ribosomal_L3 PF00297.17 GAM25428.1 - 1.2e-116 388.6 5.0 1.6e-116 388.3 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2042 PF09743.4 GAM25428.1 - 0.0082 15.4 0.2 0.012 14.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) GST_N PF02798.15 GAM25429.1 - 4.3e-13 49.2 0.0 9.2e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM25429.1 - 2e-08 34.0 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM25429.1 - 3.5e-07 30.6 0.0 1.3e-06 28.8 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM25429.1 - 5e-06 26.6 0.0 9.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM25429.1 - 0.00046 20.0 0.0 0.0033 17.2 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM25429.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArfGap PF01412.13 GAM25430.1 - 7.5e-30 103.1 0.1 7.5e-30 103.1 0.0 2.8 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf DUF2092 PF09865.4 GAM25430.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Ribosomal_L30 PF00327.15 GAM25431.1 - 2.1e-18 65.6 0.6 4.1e-18 64.6 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 GAM25431.1 - 3.2e-07 30.2 12.1 7e-07 29.1 8.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Sod_Cu PF00080.15 GAM25432.1 - 5e-49 166.1 1.7 7e-49 165.6 1.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2615 PF11027.3 GAM25432.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) ODV-E18 PF10717.4 GAM25432.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3357 PF11837.3 GAM25432.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) RCR PF12273.3 GAM25432.1 - 1.1 9.8 4.1 1.8 9.1 0.0 2.2 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TPR_11 PF13414.1 GAM25433.1 - 8.6e-46 153.4 22.8 1.1e-16 60.1 1.7 5.5 3 2 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 GAM25433.1 - 2.1e-33 112.5 27.8 3.2e-09 35.9 0.3 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAM25433.1 - 5.8e-33 110.1 18.7 1.7e-06 27.4 0.1 8.3 9 0 0 9 9 9 5 Tetratricopeptide repeat DnaJ PF00226.26 GAM25433.1 - 2.1e-25 88.2 2.3 6.2e-25 86.7 1.6 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 GAM25433.1 - 4e-20 71.9 18.7 7.1e-05 23.0 0.5 7.1 5 1 2 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 GAM25433.1 - 5.2e-18 65.2 5.3 1.6e-06 28.5 0.1 6.2 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAM25433.1 - 9.6e-18 62.5 18.3 0.00045 19.8 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM25433.1 - 6.5e-15 54.2 0.6 0.013 16.0 0.0 7.3 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM25433.1 - 1.7e-12 46.5 18.0 1.1e-05 25.2 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM25433.1 - 2e-12 47.0 19.3 0.00049 20.1 3.8 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAM25433.1 - 3.4e-11 42.9 17.5 4.9e-05 23.1 1.2 5.8 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM25433.1 - 1.8e-09 36.6 7.9 0.0077 15.9 0.1 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM25433.1 - 2.1e-05 24.2 3.2 0.57 10.0 0.1 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAM25433.1 - 0.00013 21.1 13.9 0.036 13.1 5.6 3.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM25433.1 - 0.003 17.4 7.3 5.9 6.8 0.1 5.9 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 GAM25433.1 - 0.0045 17.2 1.8 0.15 12.3 0.4 3.7 4 1 0 4 4 3 1 Bacterial transcriptional activator domain SHNi-TPR PF10516.4 GAM25433.1 - 0.027 13.6 11.7 0.51 9.6 0.1 5.5 6 0 0 6 6 6 0 SHNi-TPR MIT PF04212.13 GAM25433.1 - 0.11 12.3 17.2 0.11 12.3 0.5 6.0 5 1 3 8 8 8 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 GAM25433.1 - 0.19 12.2 24.5 0.78 10.3 0.1 7.3 10 1 0 10 10 8 0 Tetratricopeptide repeat Cnd3 PF12719.2 GAM25434.1 - 6.5e-17 61.4 4.9 8.4e-17 61.0 1.7 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 GAM25434.1 - 2e-08 34.3 0.0 7.7e-05 22.8 0.0 4.1 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 GAM25434.1 - 6.6e-08 32.0 1.7 8.8 6.7 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 GAM25434.1 - 0.0013 19.1 0.1 3.9 8.0 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat FNIP PF05725.7 GAM25435.1 - 1.4e-88 290.6 40.6 9.2e-13 47.9 1.1 12.4 8 2 5 13 13 13 12 FNIP Repeat Nucleoplasmin PF03066.10 GAM25436.1 - 0.013 15.0 5.7 0.027 13.9 4.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin Nop25 PF09805.4 GAM25436.1 - 0.017 15.1 7.0 0.041 13.9 4.9 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Cwf_Cwc_15 PF04889.7 GAM25436.1 - 0.021 14.5 8.3 0.04 13.6 5.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Senescence_reg PF04520.8 GAM25436.1 - 0.025 15.0 3.0 0.042 14.3 2.1 1.3 1 0 0 1 1 1 0 Senescence regulator eIF-3c_N PF05470.7 GAM25436.1 - 0.062 11.3 4.6 0.083 10.9 3.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3474 PF11960.3 GAM25436.1 - 0.1 12.5 2.3 0.19 11.7 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) NOA36 PF06524.7 GAM25436.1 - 0.24 10.6 2.6 0.48 9.6 1.8 1.5 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 GAM25436.1 - 0.39 10.3 4.1 0.99 9.0 2.3 2.1 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.5 GAM25436.1 - 0.74 10.0 10.3 2 8.7 7.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.3 GAM25436.1 - 3.2 7.6 19.7 0.037 13.9 6.4 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 TIG PF01833.19 GAM25437.1 - 1.7e-26 91.9 74.8 2e-07 30.8 6.0 8.9 10 1 0 10 10 10 6 IPT/TIG domain EGF_2 PF07974.8 GAM25437.1 - 0.11 12.6 11.9 0.21 11.7 8.2 1.5 1 0 0 1 1 1 0 EGF-like domain F5_F8_type_C PF00754.20 GAM25438.1 - 2.6e-20 72.5 0.5 4e-20 71.9 0.3 1.3 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 GAM25438.1 - 8.3e-17 60.6 0.1 1.7e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 H-type lectin domain Choline_transpo PF04515.7 GAM25439.1 - 6.7e-78 261.7 44.3 2.2e-77 260.0 27.4 2.5 1 1 1 2 2 2 2 Plasma-membrane choline transporter DUF2371 PF10177.4 GAM25439.1 - 0.06 13.2 0.0 0.06 13.2 0.0 3.9 5 0 0 5 5 5 0 Uncharacterised conserved protein (DUF2371) Sec1 PF00995.18 GAM25440.1 - 7.2e-136 454.0 8.5 8.4e-136 453.8 5.9 1.0 1 0 0 1 1 1 1 Sec1 family Syja_N PF02383.13 GAM25441.1 - 2.3e-80 269.7 0.2 2.9e-80 269.3 0.2 1.1 1 0 0 1 1 1 1 SacI homology domain eRF1_2 PF03464.10 GAM25442.1 - 5.2e-42 143.3 0.0 1e-41 142.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAM25442.1 - 2.2e-35 121.3 0.4 7.3e-35 119.6 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 GAM25442.1 - 3.6e-23 81.5 0.1 6.4e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Inhibitor_I78 PF11720.3 GAM25442.1 - 0.043 13.5 0.2 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Peptidase inhibitor I78 family AA_permease_2 PF13520.1 GAM25443.1 - 4.7e-55 186.8 53.1 4.7e-55 186.8 36.8 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 GAM25443.1 - 1.9e-42 145.2 46.6 1.9e-42 145.2 32.3 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 GAM25443.1 - 6.1e-18 64.4 1.6 6.1e-18 64.4 1.1 4.2 4 0 0 4 4 4 1 C-terminus of AA_permease Spore_permease PF03845.8 GAM25443.1 - 2.2e-06 26.5 22.4 2.2e-06 26.5 15.5 2.9 3 1 0 3 3 3 1 Spore germination protein SET PF00856.23 GAM25444.1 - 5.9e-08 33.1 0.0 1.2e-05 25.6 0.0 2.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 GAM25444.1 - 1.4e-05 24.8 3.4 1.4e-05 24.8 2.4 2.4 2 0 0 2 2 2 1 MYND finger FNIP PF05725.7 GAM25445.1 - 4.6e-14 52.0 15.4 5e-08 32.7 0.4 6.5 6 1 1 7 7 7 2 FNIP Repeat MutS_V PF00488.16 GAM25446.1 - 3.2e-90 301.6 0.0 5.2e-90 300.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 GAM25446.1 - 2.6e-32 112.2 0.2 5.8e-32 111.1 0.2 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 GAM25446.1 - 4.1e-28 97.6 0.3 1.4e-27 95.9 0.2 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 GAM25446.1 - 6.4e-14 52.1 0.1 3.3e-13 49.8 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 GAM25446.1 - 1.8e-10 40.8 2.9 6.2e-10 39.1 2.0 2.0 1 0 0 1 1 1 1 MutS family domain IV MatE PF01554.13 GAM25447.1 - 0.00015 21.4 19.8 0.0016 18.1 5.1 3.9 2 2 1 3 3 3 2 MatE FtsH_ext PF06480.10 GAM25447.1 - 0.14 12.2 0.5 0.14 12.2 0.3 2.4 2 1 0 2 2 2 0 FtsH Extracellular DNA_pol_A_exo1 PF01612.15 GAM25448.1 - 2.6e-17 62.8 0.0 7.1e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease FerA PF08165.6 GAM25448.1 - 0.0031 17.1 1.0 0.019 14.6 0.1 2.3 2 0 0 2 2 2 1 FerA (NUC095) domain COX14 PF14880.1 GAM25448.1 - 0.044 13.4 0.6 0.097 12.3 0.1 1.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF846 PF05832.7 GAM25449.1 - 4.2e-47 159.4 13.9 5.2e-47 159.1 9.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) CbiQ PF02361.11 GAM25449.1 - 0.62 9.5 9.6 0.82 9.1 6.6 1.1 1 0 0 1 1 1 0 Cobalt transport protein Tic20 PF09685.5 GAM25449.1 - 2.2 8.2 11.8 5.6 6.9 0.7 2.3 2 0 0 2 2 2 0 Tic20-like protein Y_phosphatase PF00102.22 GAM25450.1 - 6.9e-09 35.3 0.0 8.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 GAM25450.1 - 2.8e-08 33.4 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 GAM25450.1 - 2.7e-05 23.6 0.0 4e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 GAM25450.1 - 0.00033 20.7 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate MOZART1 PF12554.3 GAM25450.1 - 0.12 11.8 0.1 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF2207 PF09972.4 GAM25451.1 - 0.068 11.7 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ala_racemase_N PF01168.15 GAM25452.1 - 6e-39 133.8 0.0 6.7e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PH PF00169.24 GAM25453.1 - 1.3e-27 95.9 1.3 5.5e-11 42.6 0.1 3.6 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 GAM25453.1 - 7.6e-11 42.2 12.1 0.012 15.8 0.4 5.5 4 2 2 6 6 6 4 Pleckstrin homology domain PH_9 PF15410.1 GAM25453.1 - 0.0057 16.8 0.3 0.079 13.1 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain GSHPx PF00255.14 GAM25454.1 - 0.0013 18.1 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase GSHPx PF00255.14 GAM25455.1 - 7.7e-17 60.6 0.1 9.8e-17 60.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase HMG_box PF00505.14 GAM25456.1 - 2.3e-08 34.1 0.1 4.1e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM25456.1 - 0.00015 22.1 0.3 0.00024 21.4 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 GAM25456.1 - 0.063 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF1014 PF06244.7 GAM25456.1 - 0.092 12.9 0.3 0.19 11.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) Cut8_C PF08559.5 GAM25457.1 - 1.2e-14 54.3 2.1 1.2e-14 54.3 1.5 2.7 2 1 0 2 2 2 1 Cut8 six-helix bundle Med15 PF09606.5 GAM25457.1 - 7.9e-06 24.3 53.8 8.9e-06 24.2 37.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Otopetrin PF03189.8 GAM25457.1 - 0.054 12.4 4.9 0.069 12.1 3.4 1.4 1 0 0 1 1 1 0 Otopetrin LMBR1 PF04791.11 GAM25457.1 - 1.6 7.1 4.2 2.6 6.5 2.9 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.13 GAM25457.1 - 2.1 6.5 4.9 2.4 6.3 3.4 1.2 1 0 0 1 1 1 0 Membrane transport protein ACOX PF01756.14 GAM25458.1 - 2.1e-14 53.3 0.0 3.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAM25458.1 - 1.8e-10 40.1 0.0 4.2e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 GAM25458.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 GAM25458.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM25458.1 - 0.16 12.5 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain 7tm_2 PF00002.19 GAM25459.1 - 0.00041 19.4 1.9 0.00098 18.2 1.3 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.12 GAM25459.1 - 0.00055 18.8 0.7 0.0014 17.5 0.2 1.8 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region Git3_C PF11970.3 GAM25459.1 - 0.0092 15.7 0.1 0.03 14.1 0.1 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3481 PF11980.3 GAM25459.1 - 0.16 11.8 0.0 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) EpsG PF14897.1 GAM25459.1 - 0.2 10.5 18.0 0.07 12.0 5.3 2.8 2 1 0 2 2 2 0 EpsG family MitMem_reg PF13012.1 GAM25460.1 - 6.7e-24 84.1 0.0 1.4e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAM25460.1 - 1e-20 73.5 0.0 1.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DNA_topoisoIV PF00521.15 GAM25461.1 - 4.1e-116 388.3 0.7 6.1e-116 387.7 0.5 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 GAM25461.1 - 3.8e-31 107.6 1.0 9.4e-31 106.3 0.7 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 GAM25461.1 - 1.4e-11 44.1 0.0 8.4e-11 41.7 0.0 2.4 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 GAM25461.1 - 1.2e-09 37.8 0.1 6e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nucleoporin_FG PF13634.1 GAM25461.1 - 0.23 11.7 9.5 0.036 14.2 3.3 2.2 2 0 0 2 2 2 0 Nucleoporin FG repeat region PHD PF00628.24 GAM25462.1 - 1.2e-09 37.6 7.4 1.2e-09 37.6 5.1 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 GAM25462.1 - 0.095 12.8 1.4 0.24 11.5 0.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 GAM25462.1 - 1.3 9.0 6.5 2.6 8.1 4.5 1.5 1 0 0 1 1 1 0 RING-like domain ADK_lid PF05191.9 GAM25462.1 - 2.6 7.7 7.4 0.2 11.3 1.2 2.1 2 0 0 2 2 2 0 Adenylate kinase, active site lid Secretin_N_2 PF07655.8 GAM25464.1 - 0.73 10.2 5.6 0.79 10.1 3.9 1.3 1 1 0 1 1 1 0 Secretin N-terminal domain Coiled PF05710.7 GAM25464.1 - 1.2 9.6 12.1 1.6 9.2 8.4 1.2 1 0 0 1 1 1 0 Coiled coil RNA_pol_L_2 PF13656.1 GAM25465.1 - 2.4e-27 94.1 0.1 3.1e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 GAM25465.1 - 2e-09 36.4 0.0 2.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Death PF00531.17 GAM25466.1 - 0.03 14.0 2.0 3.4 7.4 0.0 3.4 3 2 0 3 3 3 0 Death domain Nuf2 PF03800.9 GAM25466.1 - 0.065 13.2 0.1 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Nuf2 family Clathrin_bdg PF15045.1 GAM25466.1 - 0.077 12.5 0.1 0.72 9.3 0.0 2.4 2 1 1 3 3 3 0 Clathrin-binding box of Aftiphilin, vesicle trafficking MAT1 PF06391.8 GAM25466.1 - 6.2 6.3 10.0 1.7 8.1 4.2 1.8 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 FNIP PF05725.7 GAM25467.1 - 5.2e-46 154.3 21.5 9e-13 47.9 0.2 8.6 7 1 2 9 9 9 8 FNIP Repeat Caps_synth_CapC PF14102.1 GAM25468.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Capsule biosynthesis CapC Lipoxygenase PF00305.14 GAM25469.1 - 3.8e-67 226.7 0.4 4.9e-67 226.4 0.3 1.0 1 0 0 1 1 1 1 Lipoxygenase HATPase_c PF02518.21 GAM25470.1 - 6.9e-26 90.1 0.0 1.3e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM25470.1 - 2.4e-18 66.1 0.1 6.3e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM25470.1 - 1.3e-11 44.2 0.0 3.8e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 GAM25470.1 - 5.3e-08 32.8 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 GAM25470.1 - 1.4e-07 31.3 0.7 7e-07 29.0 0.0 2.6 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 GAM25470.1 - 1.4e-07 31.8 0.0 5e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 GAM25470.1 - 6.1e-07 29.0 0.0 8.6e-05 22.2 0.0 2.7 2 0 0 2 2 2 1 PAS domain Methyltransf_2 PF00891.13 GAM25471.1 - 2.4e-51 174.2 0.0 2.9e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HTH_IclR PF09339.5 GAM25471.1 - 0.0026 17.3 0.0 0.057 13.0 0.0 2.5 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.1 GAM25471.1 - 0.0031 16.8 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 GAM25471.1 - 0.015 15.3 0.1 0.16 11.9 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 GAM25471.1 - 0.016 14.7 0.0 2.2 7.8 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_Tnp_1_2 PF13022.1 GAM25471.1 - 0.036 13.8 0.2 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix of insertion element transposase DUF2594 PF10769.4 GAM25471.1 - 0.054 13.5 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) TrmB PF01978.14 GAM25471.1 - 0.11 12.2 0.0 0.4 10.4 0.0 1.9 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_20 PF12840.2 GAM25471.1 - 0.13 12.0 0.0 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain IFN-gamma PF00714.12 GAM25471.1 - 0.14 11.9 1.1 0.25 11.1 0.7 1.3 1 0 0 1 1 1 0 Interferon gamma Pkinase PF00069.20 GAM25472.1 - 2.5e-52 177.6 0.0 2.5e-52 177.6 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25472.1 - 1.1e-27 96.6 0.0 2.5e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.7 GAM25472.1 - 3.4e-05 23.6 0.2 0.00022 21.0 0.1 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Kdo PF06293.9 GAM25472.1 - 0.00083 18.4 0.2 0.0021 17.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM25472.1 - 0.0036 16.6 0.5 0.0098 15.2 0.3 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 GAM25472.1 - 0.019 14.6 0.1 0.019 14.6 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family FNIP PF05725.7 GAM25473.1 - 2.1e-44 149.2 12.7 5e-14 51.9 0.2 7.3 7 1 0 7 7 7 5 FNIP Repeat DUF1769 PF08588.5 GAM25473.1 - 0.0059 16.5 0.4 1.6 8.7 0.1 3.7 2 1 2 4 4 4 2 Protein of unknown function (DUF1769) Kelch_6 PF13964.1 GAM25474.1 - 1.4e-38 129.5 11.0 1.9e-09 37.2 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.1 GAM25474.1 - 3.9e-38 128.9 22.3 1.7e-08 34.0 0.2 6.9 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25474.1 - 1.8e-32 110.6 16.0 7.9e-09 34.9 0.1 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.1 GAM25474.1 - 4e-32 109.6 19.7 2.3e-10 40.3 0.0 8.0 8 0 0 8 8 8 7 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM25474.1 - 2e-29 101.0 6.5 9.1e-05 22.3 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM25474.1 - 6e-29 98.6 12.4 8.2e-09 34.8 0.1 7.5 6 1 0 6 6 6 6 Kelch motif F-box-like PF12937.2 GAM25474.1 - 3.9e-06 26.4 0.1 1.3e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM25474.1 - 0.024 14.3 0.4 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 F-box domain GATA PF00320.22 GAM25474.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 GATA zinc finger CH PF00307.26 GAM25475.1 - 4.7e-31 107.0 0.1 3.1e-18 65.7 0.0 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain HemY_N PF07219.8 GAM25477.1 - 0.063 12.8 0.7 0.08 12.5 0.5 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Pkinase PF00069.20 GAM25478.1 - 3.4e-05 23.1 0.1 0.00015 21.0 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain QCR10 PF09796.4 GAM25480.1 - 0.075 12.7 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) zf-DNL PF05180.7 GAM25480.1 - 0.19 11.4 0.7 40 4.0 0.0 3.4 3 0 0 3 3 3 0 DNL zinc finger Aida_C2 PF14186.1 GAM25480.1 - 0.3 10.3 2.1 5.3 6.2 0.1 2.6 3 0 0 3 3 3 0 Cytoskeletal adhesion Cnd2 PF05786.9 GAM25482.1 - 4.5e-129 432.1 20.1 2.1e-128 429.8 13.9 1.9 1 1 0 1 1 1 1 Condensin complex subunit 2 CENP-B_dimeris PF09026.5 GAM25483.1 - 0.15 12.3 3.3 0.26 11.5 2.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DEAD PF00270.24 GAM25484.1 - 8.3e-39 132.7 0.5 1.2e-37 128.9 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM25484.1 - 1.9e-22 78.8 0.6 6.3e-22 77.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 GAM25484.1 - 0.033 13.2 0.0 0.033 13.2 0.0 3.0 4 0 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit FNIP PF05725.7 GAM25485.1 - 3.6e-90 295.7 30.0 1.9e-14 53.3 0.0 11.2 6 3 4 11 11 11 11 FNIP Repeat RRM_1 PF00076.17 GAM25486.1 - 7.8e-22 76.7 0.1 1.4e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 GAM25486.1 - 3.7e-15 55.7 15.5 3.7e-15 55.7 10.8 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 GAM25486.1 - 1.1e-12 47.7 0.1 6.4e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25486.1 - 5.5e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlbT PF07378.6 GAM25486.1 - 0.1 12.4 0.6 0.18 11.6 0.4 1.3 1 0 0 1 1 1 0 Flagellar protein FlbT adh_short PF00106.20 GAM25487.1 - 3.7e-14 52.9 0.0 5.5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM25487.1 - 1.6e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM25487.1 - 4.2e-05 23.1 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DDE_Tnp_4 PF13359.1 GAM25487.1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Shikimate_DH PF01488.15 GAM25487.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bromodomain PF00439.20 GAM25488.1 - 1.1e-20 73.2 1.5 1.7e-20 72.7 0.2 2.0 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 GAM25488.1 - 1.3e-08 34.4 0.1 3.7e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated Prenyltransf PF01255.14 GAM25489.1 - 0.047 12.8 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Metallophos PF00149.23 GAM25490.1 - 5e-11 42.3 2.6 8.2e-11 41.6 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_1 PF05184.10 GAM25490.1 - 0.006 16.3 1.4 0.014 15.1 1.0 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 SapB_2 PF03489.12 GAM25490.1 - 0.083 12.9 1.4 0.15 12.1 0.3 2.0 2 0 0 2 2 2 0 Saposin-like type B, region 2 CorA PF01544.13 GAM25491.1 - 1.7e-50 171.7 7.5 1.9e-33 115.7 2.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein MARVEL PF01284.18 GAM25491.1 - 0.034 13.9 1.5 0.061 13.1 1.1 1.4 1 0 0 1 1 1 0 Membrane-associating domain Colicin-DNase PF12639.2 GAM25492.1 - 0.083 13.1 2.9 0.74 10.0 2.0 2.0 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Meiotic_rec114 PF03525.9 GAM25493.1 - 0.0006 18.4 1.9 0.00065 18.3 1.3 1.0 1 0 0 1 1 1 1 Meiotic recombination protein rec114 DUF4557 PF15101.1 GAM25493.1 - 0.035 13.9 0.2 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tox-HDC PF15656.1 GAM25493.1 - 0.14 12.3 0.7 0.18 11.9 0.5 1.2 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Rap_GAP PF02145.10 GAM25494.1 - 6.4e-58 195.2 0.1 1.1e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Prenyltransf PF01255.14 GAM25495.1 - 0.0076 15.4 0.3 0.011 14.9 0.2 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cytochrom_C552 PF02335.10 GAM25495.1 - 0.062 11.9 0.1 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c552 FYVE PF01363.16 GAM25496.1 - 1.8e-06 27.7 12.2 6.1e-06 26.0 8.5 1.9 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 GAM25497.1 - 0.00081 19.2 4.3 0.0022 17.8 3.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 GAM25497.1 - 0.00093 18.8 1.9 0.0025 17.4 1.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Sina PF03145.11 GAM25497.1 - 0.0014 18.3 1.7 0.98 9.0 0.3 2.5 2 0 0 2 2 2 2 Seven in absentia protein family zf-RING_UBOX PF13445.1 GAM25497.1 - 0.0027 17.3 1.4 0.0098 15.5 1.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 GAM25497.1 - 0.0033 17.0 4.8 0.01 15.5 3.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM25497.1 - 0.0069 16.3 4.6 0.019 14.9 3.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM25497.1 - 0.017 14.9 2.4 0.053 13.3 1.7 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 GAM25497.1 - 0.018 14.8 1.3 0.044 13.5 0.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein ADIP PF11559.3 GAM25497.1 - 0.14 12.0 2.6 0.24 11.2 1.8 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TM2 PF05154.11 GAM25498.1 - 1e-20 73.6 8.5 1.4e-20 73.2 5.9 1.2 1 0 0 1 1 1 1 TM2 domain MIG-14_Wnt-bd PF06664.7 GAM25498.1 - 0.019 13.8 0.3 0.021 13.6 0.2 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion YppG PF14179.1 GAM25498.1 - 3.1 8.4 12.4 3.7 8.2 8.6 1.1 1 0 0 1 1 1 0 YppG-like protein DUF4605 PF15378.1 GAM25498.1 - 7.3 6.3 6.8 19 5.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) ubiquitin PF00240.18 GAM25500.1 - 9.5e-35 117.8 0.6 1.2e-34 117.4 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 GAM25500.1 - 5.1e-30 102.8 10.5 8.4e-30 102.1 7.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 GAM25500.1 - 1.7e-19 69.2 0.4 2.2e-19 68.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 GAM25500.1 - 1.1e-05 25.5 0.1 4.1e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 GAM25500.1 - 0.00093 18.9 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 GAM25500.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 GAM25500.1 - 0.047 13.8 0.1 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 GAM25500.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Orn_Arg_deC_N PF02784.11 GAM25501.1 - 7.1e-43 146.6 0.0 9.4e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 GAM25501.1 - 1.1e-10 41.2 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ded_cyto PF06920.8 GAM25503.1 - 1.9e-29 102.2 0.2 4.5e-29 101.0 0.1 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis F-box-like PF12937.2 GAM25503.1 - 3.9e-09 36.0 0.9 8.2e-09 35.0 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM25503.1 - 0.00036 20.0 0.0 0.00087 18.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.1 GAM25504.1 - 0.0025 17.4 12.7 0.77 9.6 1.4 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM25504.1 - 0.0074 16.0 1.5 5.3 7.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM25504.1 - 0.016 15.1 32.4 0.53 10.2 0.0 8.6 8 2 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM25504.1 - 0.033 13.8 34.2 0.13 11.8 1.4 7.1 8 0 0 8 8 8 0 TPR repeat AA_permease_2 PF13520.1 GAM25505.1 - 1.6e-57 194.9 39.9 1.6e-57 194.9 27.6 2.1 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 GAM25505.1 - 2.5e-42 144.8 39.3 2.5e-42 144.8 27.2 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 GAM25505.1 - 8.9e-23 79.9 9.0 8.9e-23 79.9 6.2 3.8 4 0 0 4 4 4 1 C-terminus of AA_permease EF-hand_7 PF13499.1 GAM25506.1 - 4e-17 62.1 9.7 2.2e-10 40.5 0.3 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM25506.1 - 3.8e-16 57.0 9.6 2.3e-05 23.3 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 GAM25506.1 - 1.4e-15 55.6 1.2 5.5e-05 22.7 0.1 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM25506.1 - 9.1e-12 44.4 4.0 6.5e-07 28.8 0.7 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM25506.1 - 5.9e-10 38.0 9.1 0.0036 16.5 0.2 4.4 4 0 0 4 4 4 3 EF hand TSC22 PF01166.13 GAM25506.1 - 0.00021 21.1 6.3 0.0027 17.6 0.7 8.9 7 3 3 10 10 10 2 TSC-22/dip/bun family EF-hand_9 PF14658.1 GAM25506.1 - 0.0014 18.5 0.4 0.047 13.6 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain Spc42p PF11544.3 GAM25506.1 - 0.012 15.4 4.9 0.012 15.4 3.4 6.6 6 1 1 7 7 7 0 Spindle pole body component Spc42p Myosin_tail_1 PF01576.14 GAM25506.1 - 8.3 3.9 81.3 1.4 6.4 8.4 3.6 3 0 0 3 3 3 0 Myosin tail GST_N_3 PF13417.1 GAM25508.1 - 2.9e-11 43.4 0.0 1e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM25508.1 - 2.1e-09 37.2 0.2 3.4e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM25508.1 - 1.2e-07 31.5 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM25508.1 - 3.3e-05 24.2 0.1 4.5e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM25508.1 - 0.0002 21.4 0.0 0.00071 19.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM25508.1 - 0.0046 16.8 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PH PF00169.24 GAM25509.1 - 2e-12 47.2 0.7 6e-12 45.6 0.5 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM25509.1 - 0.00016 21.9 0.6 0.00048 20.3 0.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1054 PF06335.7 GAM25509.1 - 0.11 12.1 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1054) Mcp5_PH PF12814.2 GAM25509.1 - 0.21 11.4 2.5 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Coiled PF05710.7 GAM25510.1 - 0.0051 17.2 23.2 0.0059 17.0 16.1 1.1 1 0 0 1 1 1 1 Coiled coil EAF PF09816.4 GAM25511.1 - 1.9e-17 63.1 0.1 5.1e-17 61.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF4551 PF15087.1 GAM25511.1 - 1.8 6.8 9.3 2.6 6.3 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.5 GAM25511.1 - 2.4 6.4 7.7 3.6 5.8 5.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nitrate_red_gam PF02665.9 GAM25512.1 - 0.016 14.5 0.4 0.028 13.7 0.2 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit zf-met PF12874.2 GAM25512.1 - 0.021 15.0 0.1 0.021 15.0 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 GAM25512.1 - 0.03 14.4 2.7 0.033 14.3 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 GAM25512.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.0 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) DUF4326 PF14216.1 GAM25513.1 - 3e-23 82.1 0.1 4.8e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) MtrH PF02007.13 GAM25513.1 - 0.13 11.2 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit FGGY_N PF00370.16 GAM25515.1 - 6.2e-46 156.7 0.3 1.8e-44 151.9 0.2 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 GAM25515.1 - 2.5e-38 131.6 1.0 1.1e-37 129.6 0.1 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SSP160 PF06933.6 GAM25515.1 - 4.6 5.1 17.1 7.5 4.3 11.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 2-oxoacid_dh PF00198.18 GAM25516.1 - 1.9e-80 269.4 0.0 2.7e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM25516.1 - 1.1e-38 130.6 2.4 1.1e-18 66.6 0.1 2.8 3 0 0 3 3 3 2 Biotin-requiring enzyme E3_binding PF02817.12 GAM25516.1 - 2.7e-15 55.7 0.5 2.7e-15 55.7 0.4 2.7 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 GAM25516.1 - 1.5e-06 27.7 0.0 0.016 14.8 0.0 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.1 GAM25516.1 - 0.0046 16.6 0.2 2 8.1 0.0 2.9 2 1 0 2 2 2 2 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 GAM25516.1 - 0.017 14.8 0.1 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Glycine cleavage H-protein QRPTase_N PF02749.11 GAM25516.1 - 0.02 14.6 0.0 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_2 PF12700.2 GAM25516.1 - 0.097 11.8 7.9 1 8.4 0.0 3.2 3 0 0 3 3 3 0 HlyD family secretion protein DUF2360 PF10152.4 GAM25516.1 - 2 8.6 9.1 8.5 6.6 1.3 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Sulfate_transp PF00916.15 GAM25517.1 - 6.3e-69 232.0 9.4 1e-68 231.4 6.5 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM25517.1 - 9.4e-34 114.9 2.5 9.4e-34 114.9 1.7 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM25517.1 - 1.1e-21 76.4 0.1 2.1e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 GAM25518.1 - 6.3e-35 117.8 30.8 1.4e-09 37.4 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat FNIP PF05725.7 GAM25519.1 - 1e-65 217.4 37.7 7.2e-15 54.6 0.3 7.4 5 2 4 9 9 9 7 FNIP Repeat RRM_1 PF00076.17 GAM25520.1 - 1.1e-75 249.2 2.0 2.3e-17 62.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25520.1 - 8.1e-64 211.5 0.6 1.1e-15 57.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25520.1 - 1.4e-40 136.8 0.0 8.5e-10 38.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 GAM25520.1 - 0.0031 17.4 0.0 0.13 12.3 0.0 3.4 4 0 0 4 4 4 1 RNA binding domain Nup35_RRM_2 PF14605.1 GAM25520.1 - 0.0036 17.0 0.0 3.6 7.4 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 GAM25520.1 - 0.0069 16.3 0.8 29 4.7 0.0 3.7 3 0 0 3 3 3 0 RNA recognition motif 2 zf-CCCH PF00642.19 GAM25521.1 - 3.1e-08 33.0 17.7 0.00025 20.6 3.0 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SAM_1 PF00536.25 GAM25521.1 - 2.7e-07 30.6 0.4 7.5e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM25521.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCCH_2 PF14608.1 GAM25521.1 - 0.0079 16.1 5.5 0.0079 16.1 3.8 3.3 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type Orbi_VP6 PF01516.11 GAM25521.1 - 0.063 12.3 2.7 0.097 11.7 1.9 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 Reovirus_cap PF00979.12 GAM25521.1 - 0.51 9.2 7.6 1.3 7.9 5.3 1.8 1 1 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 APC_CDC26 PF10471.4 GAM25521.1 - 0.63 10.8 16.8 0.066 13.9 3.2 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Linker_histone PF00538.14 GAM25522.1 - 2.3e-20 72.4 0.0 5e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_C39_2 PF13529.1 GAM25522.1 - 0.0096 16.2 0.9 0.0096 16.2 0.6 1.7 1 1 0 2 2 2 1 Peptidase_C39 like family Fork_head PF00250.13 GAM25522.1 - 0.075 13.0 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Fork head domain Phage_term_smal PF05944.7 GAM25522.1 - 0.083 12.5 1.6 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Phage small terminase subunit HC2 PF07382.6 GAM25522.1 - 0.38 10.5 65.5 1.7e+02 1.9 45.4 2.0 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 FAD_binding_6 PF00970.19 GAM25523.1 - 4.7e-32 110.0 0.0 7.6e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM25523.1 - 3.2e-26 92.0 0.0 4.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 GAM25523.1 - 1.2e-05 25.2 0.0 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 GAM25523.1 - 0.00044 20.2 0.0 0.00086 19.2 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF2644 PF10841.3 GAM25523.1 - 0.2 11.7 0.9 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Coiled PF05710.7 GAM25524.1 - 0.017 15.5 13.3 0.037 14.4 9.2 1.5 1 1 0 1 1 1 0 Coiled coil Hus1 PF04005.7 GAM25525.1 - 3.4e-50 170.6 5.0 2.9e-49 167.5 3.4 1.9 1 1 0 1 1 1 1 Hus1-like protein FXR1P_C PF12235.3 GAM25526.1 - 0.21 11.6 2.3 0.4 10.7 1.6 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal DPBB_1 PF03330.13 GAM25527.1 - 8.1e-15 54.5 0.5 5.4e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 GAM25527.1 - 0.00049 19.8 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.12 GAM25527.1 - 0.0016 18.0 0.1 0.0065 16.1 0.0 2.0 2 0 0 2 2 2 1 Barwin family Cerato-platanin PF07249.7 GAM25527.1 - 0.052 13.5 0.5 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Cerato-platanin V-SNARE_C PF12352.3 GAM25528.1 - 2e-08 34.1 1.1 5.5e-08 32.7 0.7 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Mucin PF01456.12 GAM25528.1 - 2.4e-05 24.1 40.0 2.4e-05 24.1 27.7 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Sec20 PF03908.8 GAM25528.1 - 0.00034 20.2 0.6 0.00034 20.2 0.4 2.6 2 2 0 2 2 2 1 Sec20 V-SNARE PF05008.10 GAM25528.1 - 0.0027 17.8 7.1 0.0051 16.9 2.2 2.7 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus CK2S PF15011.1 GAM25528.1 - 0.046 13.5 1.4 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate Orai-1 PF07856.7 GAM25528.1 - 0.047 13.2 0.7 0.39 10.2 0.1 2.2 2 0 0 2 2 2 0 Mediator of CRAC channel activity DUF607 PF04678.8 GAM25528.1 - 0.11 12.3 2.7 0.2 11.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF607 TcdB_N PF12918.2 GAM25528.1 - 0.18 11.8 10.3 2.4 8.2 0.6 2.9 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain YlqD PF11068.3 GAM25528.1 - 0.4 10.7 10.7 0.18 11.8 1.9 2.2 2 0 0 2 2 2 0 YlqD protein Cep57_CLD_2 PF14197.1 GAM25528.1 - 0.62 10.0 6.8 4.5 7.3 0.3 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Synaptobrevin PF00957.16 GAM25528.1 - 1.7 8.2 6.7 0.17 11.5 1.4 1.9 2 0 0 2 2 2 0 Synaptobrevin APG6 PF04111.7 GAM25528.1 - 4.8 6.1 16.2 4 6.3 4.3 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 ThiF PF00899.16 GAM25530.1 - 5.4e-39 133.1 0.5 4.1e-38 130.2 0.2 2.1 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 GAM25530.1 - 2.6e-23 81.3 1.0 6.5e-23 80.0 0.7 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 GAM25530.1 - 1.2e-21 76.2 0.0 1.9e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 GAM25530.1 - 4e-14 51.7 1.8 8e-14 50.7 1.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 GAM25530.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 GAM25530.1 - 0.00059 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 GAM25530.1 - 0.074 12.6 1.4 0.09 12.3 0.0 1.8 2 0 0 2 2 2 0 MoeZ/MoeB domain DUF1967 PF09269.6 GAM25530.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) eIF3_subunit PF08597.5 GAM25531.1 - 1.8e-36 125.9 23.3 2.5e-36 125.4 16.1 1.2 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 7TM_GPCR_Srsx PF10320.4 GAM25532.1 - 4.5e-05 22.7 0.8 8.5e-05 21.8 0.5 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx FDC-SP PF15215.1 GAM25532.1 - 0.89 9.9 3.6 2.3 8.5 0.3 2.6 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide Tetraspannin PF00335.15 GAM25532.1 - 2 7.6 8.2 0.81 8.9 2.8 2.1 2 1 0 2 2 2 0 Tetraspanin family DUF2614 PF11023.3 GAM25532.1 - 4.1 7.2 7.5 2.3 8.0 2.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2614) RasGEF PF00617.14 GAM25533.1 - 1.2e-50 171.8 0.2 2.2e-50 171.0 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM25533.1 - 1e-07 31.9 0.3 1e-07 31.9 0.2 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif RhoGAP PF00620.22 GAM25533.1 - 1.4e-05 24.7 1.4 2.4e-05 23.9 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain GP41 PF00517.12 GAM25533.1 - 0.0011 18.5 0.2 0.94 9.0 0.0 2.7 2 0 0 2 2 2 2 Retroviral envelope protein Fib_alpha PF08702.5 GAM25533.1 - 0.012 15.7 3.0 0.012 15.7 2.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 GAM25533.1 - 0.038 13.8 10.2 0.37 10.6 1.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 GAM25533.1 - 0.14 12.5 8.4 3.7 7.9 0.4 3.0 1 1 1 2 2 2 0 SlyX DUF2951 PF11166.3 GAM25533.1 - 2.2 8.1 5.5 0.44 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HR1 PF02185.11 GAM25533.1 - 3.8 7.3 10.5 0.38 10.5 1.3 2.8 2 0 0 2 2 2 0 Hr1 repeat RHD3 PF05879.7 GAM25534.1 - 1.5e-195 651.3 15.3 1.7e-195 651.1 10.6 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 GAM25534.1 - 1.1e-07 31.2 0.1 2.7e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 GAM25534.1 - 4.7e-05 23.3 0.0 0.00022 21.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM25534.1 - 0.00031 20.6 1.7 0.00058 19.7 0.0 2.3 2 1 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 GAM25534.1 - 0.00095 19.1 1.8 0.0043 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 GAM25534.1 - 0.003 17.0 0.9 0.03 13.7 0.3 2.4 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 GAM25534.1 - 0.0052 16.6 0.0 0.023 14.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAM25534.1 - 0.007 16.8 0.0 0.029 14.8 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 GAM25534.1 - 0.023 15.0 0.8 0.065 13.5 0.0 2.1 2 1 0 2 2 2 0 ABC transporter cwf21 PF08312.7 GAM25534.1 - 0.26 11.1 8.1 0.81 9.5 0.2 3.0 3 0 0 3 3 2 0 cwf21 domain AAA_17 PF13207.1 GAM25534.1 - 0.28 12.0 2.4 1.1 10.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain Mpv17_PMP22 PF04117.7 GAM25535.1 - 6.7e-23 80.1 1.1 6.7e-23 80.1 0.8 2.7 1 1 2 3 3 3 1 Mpv17 / PMP22 family TauE PF01925.14 GAM25535.1 - 0.25 10.7 4.2 0.68 9.3 2.9 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Caveolin PF01146.12 GAM25535.1 - 0.29 10.7 2.4 0.33 10.5 0.7 1.8 1 1 1 2 2 2 0 Caveolin RPAP1_C PF08620.5 GAM25536.1 - 1.4e-23 82.4 0.1 3e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 GAM25536.1 - 7.2e-14 51.1 2.3 1.7e-13 49.8 1.6 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal Acyl_transf_3 PF01757.17 GAM25537.1 - 5.2e-27 94.5 55.8 5.5e-27 94.4 36.5 2.1 2 0 0 2 2 2 1 Acyltransferase family FNIP PF05725.7 GAM25538.1 - 1.9e-58 194.1 17.1 9.4e-14 51.1 0.2 7.4 5 1 1 7 7 7 7 FNIP Repeat PI3Ka PF00613.15 GAM25539.1 - 2.3e-55 186.6 0.3 2.3e-55 186.6 0.2 2.0 3 0 0 3 3 3 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM25539.1 - 3.6e-55 187.0 0.8 7.8e-55 185.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM25539.1 - 1.2e-24 86.7 0.1 1.2e-24 86.7 0.0 2.6 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 GAM25539.1 - 8.9e-23 80.2 3.4 1.4e-22 79.6 0.0 2.9 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain CAP PF00188.21 GAM25541.1 - 0.0017 18.8 0.3 0.0017 18.8 0.2 2.3 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Pex14_N PF04695.8 GAM25541.1 - 6.1 6.8 13.3 21 5.1 9.2 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Qn_am_d_aIII PF09099.5 GAM25542.1 - 0.071 13.4 0.0 0.63 10.3 0.0 2.5 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Cullin PF00888.17 GAM25543.1 - 8.6e-137 457.1 23.9 1.1e-136 456.8 16.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAM25543.1 - 1.2e-27 95.4 0.4 1.6e-26 91.9 0.1 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.6 GAM25543.1 - 1.9e-05 24.5 2.1 3.4e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 HbrB-like HTH_27 PF13463.1 GAM25543.1 - 0.023 15.0 0.7 0.23 11.8 0.0 2.9 3 0 0 3 3 3 0 Winged helix DNA-binding domain RPA_C PF08784.6 GAM25543.1 - 0.023 15.0 0.1 2.2 8.7 0.0 3.0 2 0 0 2 2 2 0 Replication protein A C terminal Enkurin PF13864.1 GAM25543.1 - 0.053 13.7 0.1 0.053 13.7 0.1 2.5 2 0 0 2 2 2 0 Calmodulin-binding Pkinase PF00069.20 GAM25544.1 - 4.8e-58 196.3 0.0 9.4e-58 195.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25544.1 - 1.9e-22 79.5 0.0 7.6e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM25544.1 - 0.00036 20.3 0.0 0.0019 17.9 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM25544.1 - 0.036 13.3 0.1 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 GAM25544.1 - 0.073 12.4 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.9 GAM25544.1 - 0.1 11.6 0.1 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Muted PF14942.1 GAM25545.1 - 1.3e-15 57.5 6.9 1.6e-15 57.2 4.8 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein HOOK PF05622.7 GAM25545.1 - 0.0072 14.2 10.3 0.0089 13.8 7.1 1.0 1 0 0 1 1 1 1 HOOK protein RabGAP-TBC PF00566.13 GAM25547.1 - 5.1e-30 104.5 16.3 2.3e-16 59.9 0.5 3.2 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Paramyxo_C PF01692.13 GAM25547.1 - 4.5 6.8 13.3 2 7.9 1.6 2.9 3 0 0 3 3 3 0 Paramyxovirus non-structural protein c Ly49 PF08391.5 GAM25548.1 - 1.8 8.7 6.0 1.7 8.7 4.2 1.0 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region APC_CDC26 PF10471.4 GAM25548.1 - 4.1 8.2 15.9 4.5 8.0 11.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Na_H_Exchanger PF00999.16 GAM25549.1 - 5.3e-47 160.1 41.7 6.5e-43 146.7 25.8 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Intg_mem_TP0381 PF09529.5 GAM25551.1 - 1.5e-06 27.6 10.3 1.5e-06 27.6 7.1 1.7 2 0 0 2 2 2 1 Integral membrane protein (intg_mem_TP0381) TMEM164 PF14808.1 GAM25551.1 - 0.00017 20.8 10.4 0.0011 18.1 7.0 2.1 1 1 0 1 1 1 1 TMEM164 family RhoGEF PF00621.15 GAM25553.1 - 6.3e-52 176.0 2.9 1e-51 175.3 2.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF605 PF04652.11 GAM25553.1 - 0.96 8.7 39.8 1.6 8.0 27.6 1.4 1 0 0 1 1 1 0 Vta1 like Med27 PF11571.3 GAM25554.1 - 6.2e-18 64.7 0.3 6.2e-18 64.7 0.2 2.4 2 0 0 2 2 2 1 Mediator complex subunit 27 KaiC PF06745.8 GAM25554.1 - 0.16 11.0 1.0 0.24 10.4 0.7 1.2 1 0 0 1 1 1 0 KaiC DUF3464 PF11947.3 GAM25554.1 - 1.5 8.3 5.5 3.1 7.2 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Lin-8 PF03353.10 GAM25554.1 - 2.2 7.4 18.7 5.2 6.2 13.0 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spc7_N PF15402.1 GAM25554.1 - 2.2 6.1 19.0 0.96 7.3 11.9 1.3 1 1 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4175 PF13779.1 GAM25554.1 - 2.2 5.8 27.9 3.5 5.1 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.8 GAM25554.1 - 9.4 6.2 27.5 0.13 12.2 11.9 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRM_1 PF00076.17 GAM25555.1 - 7e-50 166.5 10.6 1.3e-15 56.8 0.1 6.1 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25555.1 - 6.7e-39 131.7 0.9 2.9e-12 46.3 0.0 5.4 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25555.1 - 5.8e-19 67.6 3.1 0.00012 21.8 0.0 5.5 5 1 1 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sulfotransfer_1 PF00685.22 GAM25556.1 - 1.9e-20 73.2 2.9 4e-19 68.9 2.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 GAM25556.1 - 8.8e-05 23.4 0.0 0.0068 17.3 0.0 2.9 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_2 PF03567.9 GAM25556.1 - 0.0052 16.5 0.2 0.019 14.6 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase family PAF-AH_p_II PF03403.8 GAM25556.1 - 0.086 11.1 0.1 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II CLPTM1 PF05602.7 GAM25557.1 - 7.5e-135 450.0 7.0 9.9e-135 449.6 4.9 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 GAM25557.1 - 0.00026 20.4 1.2 0.14 11.7 0.2 3.0 2 1 0 2 2 2 2 PQ loop repeat DUF809 PF05663.6 GAM25558.1 - 0.13 12.2 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF809) EGF_2 PF07974.8 GAM25559.1 - 0.00098 19.2 31.1 0.12 12.5 6.6 2.9 2 0 0 2 2 2 2 EGF-like domain DUF4399 PF14347.1 GAM25559.1 - 0.0013 18.7 0.0 25 4.9 0.0 5.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4399) EGF PF00008.22 GAM25559.1 - 2.1 8.4 29.1 0.48 10.4 6.6 3.0 3 0 0 3 3 3 0 EGF-like domain Complex1_51K PF01512.12 GAM25560.1 - 3.8e-48 163.0 0.0 6.6e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 GAM25560.1 - 1.2e-16 59.5 0.1 1.2e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 GAM25560.1 - 1.4e-08 34.4 0.0 4.6e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 SLBB domain CorA PF01544.13 GAM25561.1 - 1.2e-47 162.3 4.2 3.2e-47 160.9 2.9 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1732 PF08340.6 GAM25561.1 - 0.016 15.0 0.3 0.043 13.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) FH2 PF02181.18 GAM25562.1 - 5.1e-77 259.2 4.2 5.1e-77 259.2 2.9 2.6 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 GAM25562.1 - 1.8e-32 112.3 3.6 1.8e-32 112.3 2.5 2.1 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAM25562.1 - 6.4e-18 64.7 2.1 6.4e-18 64.7 1.5 2.9 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain C1_1 PF00130.17 GAM25562.1 - 1.1e-07 31.4 6.9 2.1e-07 30.5 4.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 GAM25562.1 - 0.17 11.5 4.4 0.59 9.8 3.1 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain LcrG PF07216.7 GAM25562.1 - 0.23 11.5 5.5 0.24 11.4 1.3 2.7 2 0 0 2 2 2 0 LcrG protein C1_3 PF07649.7 GAM25562.1 - 0.27 11.3 4.7 0.46 10.5 3.3 1.4 1 0 0 1 1 1 0 C1-like domain DUF4206 PF13901.1 GAM25562.1 - 2.6 7.5 9.1 0.87 9.1 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) zf-Mss51 PF13824.1 GAM25562.1 - 5.8 6.8 8.1 4.5 7.2 1.9 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 WD40 PF00400.27 GAM25563.1 - 7.9e-40 133.3 23.1 7.4e-09 35.1 0.4 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF3337 PF11816.3 GAM25563.1 - 6.7e-36 124.3 7.4 3.8e-25 88.9 5.4 4.8 4 1 0 4 4 4 2 Domain of unknown function (DUF3337) DUF605 PF04652.11 GAM25563.1 - 0.0013 18.2 5.6 0.0013 18.2 3.9 3.9 4 0 0 4 4 4 1 Vta1 like MMR_HSR1 PF01926.18 GAM25564.1 - 7.5e-21 74.2 0.1 2.4e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM25564.1 - 1.6e-05 24.2 0.0 2.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM25564.1 - 2.8e-05 23.6 0.2 0.00062 19.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 GAM25564.1 - 0.00013 21.8 4.6 0.15 11.8 0.1 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 GAM25564.1 - 0.0022 17.2 0.0 0.0098 15.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 GAM25564.1 - 0.0098 15.1 0.0 0.033 13.4 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM25564.1 - 0.035 13.2 0.0 0.065 12.3 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 GAM25564.1 - 0.037 13.5 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3530 PF12048.3 GAM25564.1 - 0.85 8.5 0.0 0.85 8.5 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3530) PseudoU_synth_2 PF00849.17 GAM25565.1 - 8.2e-30 103.7 0.1 1.1e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Senescence PF06911.7 GAM25566.1 - 6.3e-17 61.8 3.6 9.6e-17 61.2 2.5 1.3 1 0 0 1 1 1 1 Senescence-associated protein PH PF00169.24 GAM25566.1 - 3.7e-06 27.0 0.1 9.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1512 PF07431.7 GAM25566.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) SPRY PF00622.23 GAM25567.1 - 1.1e-15 57.7 0.6 2.7e-10 40.3 0.1 2.6 2 0 0 2 2 2 2 SPRY domain PHD PF00628.24 GAM25567.1 - 8.6e-08 31.7 7.5 1.9e-07 30.6 5.2 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 GAM25567.1 - 0.013 15.1 2.7 0.013 15.1 1.8 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 GAM25567.1 - 0.02 15.0 4.5 0.091 12.9 3.1 2.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 GAM25567.1 - 0.036 14.0 0.3 0.036 14.0 0.2 2.7 3 0 0 3 3 3 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 GAM25567.1 - 0.13 12.1 6.2 0.24 11.2 4.3 1.5 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.2 GAM25567.1 - 1.5 8.6 7.1 5.9 6.7 4.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 GAM25567.1 - 2.3 8.0 8.3 0.26 11.0 2.6 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RNB PF00773.14 GAM25568.1 - 1e-94 317.5 0.0 2.6e-94 316.1 0.0 1.7 1 0 0 1 1 1 1 RNB domain RRM_1 PF00076.17 GAM25569.1 - 2.1e-17 62.5 0.0 3.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25569.1 - 2e-14 53.2 0.0 3.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25569.1 - 1.4e-11 44.0 0.0 2.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lge1 PF11488.3 GAM25569.1 - 0.014 15.6 1.9 0.022 14.9 0.8 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Nup35_RRM_2 PF14605.1 GAM25569.1 - 0.059 13.1 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif V_ATPase_I PF01496.14 GAM25569.1 - 0.097 10.5 0.7 0.1 10.4 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 GAM25570.1 - 7.7e-73 244.8 0.0 1.3e-72 244.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25570.1 - 1.7e-40 138.7 0.0 2.7e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM25570.1 - 0.0073 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM25570.1 - 0.033 13.9 5.3 0.058 13.1 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Glyco_hydro_18 PF00704.23 GAM25571.1 - 2.2e-09 37.2 0.6 8.8e-09 35.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Peptidase_C1 PF00112.18 GAM25572.1 - 1.8e-71 240.5 4.0 2.5e-71 240.0 2.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM25572.1 - 1.4e-15 57.2 4.2 2.4e-15 56.5 2.9 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM25572.1 - 7.2e-06 24.7 0.5 0.0018 16.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family AcetDehyd-dimer PF09290.6 GAM25573.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation LRR_4 PF12799.2 GAM25574.1 - 0.04 13.5 0.2 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ORC5_C PF14630.1 GAM25575.1 - 6.3e-38 130.7 0.1 1e-37 130.1 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Ded_cyto PF06920.8 GAM25576.1 - 1.5e-42 144.9 0.5 3.6e-42 143.6 0.3 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM25576.1 - 1.4e-35 122.6 3.6 7.4e-33 113.7 0.9 4.4 5 0 0 5 5 5 2 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.1 GAM25576.1 - 5e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM25576.1 - 0.0018 17.6 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HATPase_c PF02518.21 GAM25577.1 - 1.3e-28 98.8 0.0 2.6e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM25577.1 - 4.2e-22 78.2 0.0 7e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 GAM25577.1 - 8.4e-20 70.5 0.1 1.6e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain RasGAP PF00616.14 GAM25578.1 - 4.4e-50 170.0 0.4 9.6e-50 168.9 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 GAM25578.1 - 1.1e-17 63.5 0.2 2.6e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain FF PF01846.14 GAM25579.1 - 3e-25 87.8 7.2 3.7e-07 30.0 0.2 5.5 5 0 0 5 5 5 4 FF domain WW PF00397.21 GAM25579.1 - 3.2e-19 68.4 12.7 1.2e-10 41.0 3.2 2.8 2 0 0 2 2 2 2 WW domain DUF2276 PF10040.4 GAM25579.1 - 0.083 13.1 0.0 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2276) SNF2_N PF00176.18 GAM25580.1 - 8.5e-78 261.1 3.5 8.5e-78 261.1 2.4 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF4208 PF13907.1 GAM25580.1 - 2.6e-22 78.9 3.5 2.6e-22 78.9 2.4 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.19 GAM25580.1 - 9.6e-19 66.8 15.6 4.2e-12 45.5 0.5 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 GAM25580.1 - 3e-15 55.8 0.0 1.4e-14 53.7 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UQ_con PF00179.21 GAM25581.1 - 1.8e-46 157.0 0.1 2.5e-46 156.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM25581.1 - 0.055 13.3 0.2 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 GAM25581.1 - 0.073 12.8 0.1 0.2 11.3 0.0 2.0 1 1 0 1 1 1 0 Prokaryotic E2 family B WD40 PF00400.27 GAM25582.1 - 7.8e-14 50.9 1.2 1.2 9.0 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat RNHCP PF12647.2 GAM25583.1 - 0.46 10.3 2.8 0.54 10.1 1.9 1.1 1 0 0 1 1 1 0 RNHCP domain Ank_2 PF12796.2 GAM25584.1 - 5.1e-06 26.7 2.1 0.0078 16.5 0.1 4.1 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM25584.1 - 0.0023 17.9 1.1 19 5.8 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_2 PF12796.2 GAM25585.1 - 2.3e-05 24.6 0.0 0.23 11.8 0.1 3.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25585.1 - 0.0029 18.0 0.0 0.34 11.4 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM25585.1 - 0.031 14.4 3.9 8.3 6.9 0.1 5.3 6 1 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.1 GAM25585.1 - 0.079 13.2 0.4 5.9 7.2 0.0 3.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) VKOR PF07884.9 GAM25586.1 - 1.7e-16 60.3 15.2 1.7e-16 60.3 10.5 1.8 2 0 0 2 2 2 1 Vitamin K epoxide reductase family FNIP PF05725.7 GAM25588.1 - 4e-60 199.5 21.3 2.1e-15 56.3 0.6 5.8 6 0 0 6 6 6 5 FNIP Repeat Peptidase_M1 PF01433.15 GAM25589.1 - 7.6e-137 456.5 0.3 1e-136 456.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 GAM25589.1 - 8.8e-53 179.6 0.0 4.5e-52 177.3 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAM25589.1 - 2.1e-18 66.5 0.2 4.7e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1779 PF08680.5 GAM25589.1 - 0.06 13.2 1.1 0.084 12.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1779) GST_N_2 PF13409.1 GAM25590.1 - 5.2e-20 71.2 0.0 1.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM25590.1 - 3e-14 52.6 0.1 1.1e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 GAM25590.1 - 1.1e-08 34.9 0.0 2.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM25590.1 - 1.2e-05 25.7 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM25590.1 - 1.4e-05 25.2 0.1 0.00021 21.4 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 GAM25591.1 - 5.3e-75 247.2 0.1 5.5e-26 90.1 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 GAM25591.1 - 9.2e-21 73.7 9.6 4.4e-09 36.3 0.3 5.1 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.27 GAM25591.1 - 2.5e-20 70.1 19.6 6.3e-06 25.1 0.1 6.4 8 0 0 8 8 8 4 EF hand EF-hand_6 PF13405.1 GAM25591.1 - 2.4e-18 64.3 14.4 2.5e-05 23.7 0.3 7.6 8 0 0 8 8 8 4 EF-hand domain EF-hand_8 PF13833.1 GAM25591.1 - 5.6e-17 61.0 11.0 4.3e-05 23.0 0.5 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM25591.1 - 7.7e-15 53.4 12.2 0.0001 21.5 0.1 5.4 6 0 0 6 6 6 4 EF hand EF-hand_4 PF12763.2 GAM25591.1 - 0.00041 20.0 0.9 0.046 13.4 0.0 2.9 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAM25591.1 - 0.0045 16.8 0.0 0.56 10.1 0.0 3.6 3 1 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 GAM25591.1 - 0.018 15.0 0.4 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2404 PF10296.4 GAM25592.1 - 7.8e-07 29.1 0.2 7.7e-06 25.9 0.0 2.5 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) Na_Ca_ex PF01699.19 GAM25593.1 - 4.5e-23 81.3 27.6 1.3e-11 44.2 6.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pex24p PF06398.6 GAM25593.1 - 0.54 8.9 2.2 1.1 7.9 0.8 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF1129 PF06570.6 GAM25593.1 - 2.3 7.4 5.5 0.95 8.7 1.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1673 PF07895.6 GAM25593.1 - 7.5 6.0 7.8 0.92 9.0 0.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1673) DUF1294 PF06961.8 GAM25594.1 - 2.3e-21 75.4 0.9 4.6e-21 74.5 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1294) TauE PF01925.14 GAM25594.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF4557 PF15101.1 GAM25594.1 - 0.018 14.9 5.5 0.027 14.3 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1275 PF06912.6 GAM25594.1 - 0.031 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Hid1 PF12722.2 GAM25594.1 - 0.34 8.5 13.0 0.4 8.3 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4337 PF14235.1 GAM25594.1 - 3.1 7.6 8.2 4.1 7.2 4.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Brix PF04427.13 GAM25595.1 - 5.7e-41 140.2 0.3 7.8e-41 139.8 0.2 1.2 1 0 0 1 1 1 1 Brix domain RCC1 PF00415.13 GAM25596.1 - 3.4e-36 123.2 0.1 3.3e-10 40.0 0.0 8.7 8 3 1 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RhoGAP PF00620.22 GAM25596.1 - 1.1e-31 109.5 0.2 1.3e-30 106.0 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain RCC1_2 PF13540.1 GAM25596.1 - 3.3e-30 103.0 17.0 1.1e-06 28.0 0.1 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF3440 PF11922.3 GAM25596.1 - 0.016 14.7 3.5 0.03 13.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Myosin_tail_1 PF01576.14 GAM25596.1 - 0.031 12.0 6.6 0.044 11.5 4.6 1.2 1 0 0 1 1 1 0 Myosin tail DUF1952 PF09189.5 GAM25596.1 - 0.17 11.5 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) DUF724 PF05266.9 GAM25596.1 - 0.52 9.9 9.9 0.93 9.0 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FERM_C PF09380.5 GAM25597.1 - 0.054 13.7 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 FERM C-terminal PH-like domain Thi4 PF01946.12 GAM25598.1 - 7.8e-06 25.1 0.0 4.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 GAM25598.1 - 1.9e-05 23.7 0.1 0.0093 14.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 GAM25598.1 - 2.2e-05 24.3 0.0 5.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM25598.1 - 0.00022 20.3 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 GAM25598.1 - 0.0061 15.4 0.1 0.032 13.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 GAM25598.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.13 GAM25598.1 - 0.015 13.6 0.0 0.024 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor ThiF PF00899.16 GAM25598.1 - 0.025 14.4 0.2 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 GAM25598.1 - 0.026 13.4 0.0 0.32 9.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A LMBR1 PF04791.11 GAM25599.1 - 1.9e-05 23.4 0.8 1.9e-05 23.4 0.5 2.3 1 1 1 2 2 2 1 LMBR1-like membrane protein Ank_2 PF12796.2 GAM25599.1 - 0.00069 19.9 0.0 0.0042 17.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25599.1 - 0.016 15.7 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM25600.1 - 1.7e-102 335.9 33.9 1.1e-16 60.9 0.4 12.9 6 4 6 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25600.1 - 8.1e-81 265.1 29.2 3.7e-09 36.8 0.0 19.5 15 4 5 20 20 20 15 Ankyrin repeats (many copies) Ank PF00023.25 GAM25600.1 - 2.4e-76 247.9 28.5 2.9e-06 26.7 0.0 21.4 22 0 0 22 22 21 14 Ankyrin repeat Ank_5 PF13857.1 GAM25600.1 - 2.8e-65 214.8 26.6 1.1e-08 34.9 0.1 18.3 10 4 9 19 19 19 13 Ankyrin repeats (many copies) PARP PF00644.15 GAM25600.1 - 7.1e-60 201.9 0.0 1.6e-59 200.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_3 PF13606.1 GAM25600.1 - 7.1e-50 162.0 29.3 0.00011 22.0 0.0 20.3 22 0 0 22 22 21 9 Ankyrin repeat PARP_reg PF02877.9 GAM25600.1 - 7.2e-27 93.6 2.5 5.1e-26 90.9 1.2 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 GAM25600.1 - 2.1e-14 53.2 0.1 6.7e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 WGR domain Nop14 PF04147.7 GAM25600.1 - 0.023 12.6 12.8 0.035 12.0 8.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 GAM25600.1 - 1 8.6 11.1 19 4.5 9.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 GAM25600.1 - 2.3 6.8 23.0 3.8 6.1 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 GAM25600.1 - 3.6 5.9 12.5 5.5 5.3 8.7 1.1 1 0 0 1 1 1 0 Daxx Family B56 PF01603.15 GAM25601.1 - 2.4e-146 487.5 7.7 3e-146 487.2 5.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cyclin PF08613.6 GAM25602.1 - 3.4e-33 115.1 0.1 3.4e-33 115.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM25602.1 - 4.6e-11 42.3 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain CytochromB561_N PF09786.4 GAM25602.1 - 0.7 8.2 12.8 1.1 7.6 8.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal TFIIA PF03153.8 GAM25602.1 - 5.7 6.7 9.7 9.3 6.0 6.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Beta-lactamase PF00144.19 GAM25603.1 - 2.1e-41 142.0 0.0 2.7e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 GAM25603.1 - 0.092 12.0 0.0 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Methyltransf_23 PF13489.1 GAM25604.1 - 2.9e-15 56.3 0.0 3.5e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM25604.1 - 1.3e-14 54.4 0.0 1.9e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM25604.1 - 4.7e-14 52.2 0.0 5.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM25604.1 - 8.1e-14 51.8 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM25604.1 - 7.6e-09 36.1 0.0 1.1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM25604.1 - 1.9e-08 34.5 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM25604.1 - 1.8e-07 31.1 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 GAM25604.1 - 1.1e-05 24.3 0.1 1.6e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 GAM25604.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 GAM25604.1 - 5.3e-05 22.2 0.0 7.3e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 GAM25604.1 - 8.7e-05 22.0 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 GAM25604.1 - 9.4e-05 21.6 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.7 GAM25604.1 - 0.0006 19.1 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.9 GAM25604.1 - 0.00062 18.9 0.1 0.0021 17.2 0.1 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 GAM25604.1 - 0.014 14.4 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 GAM25604.1 - 0.029 13.4 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 GAM25604.1 - 0.05 13.2 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF1162 PF06650.7 GAM25605.1 - 5.2e-37 127.5 0.5 5.2e-37 127.5 0.4 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 GAM25605.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 ATG C terminal domain TauE PF01925.14 GAM25605.1 - 0.81 9.0 0.2 1.4 8.3 0.1 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Chorein_N PF12624.2 GAM25606.1 - 1e-38 131.4 1.5 4.4e-38 129.4 1.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ARF7EP_C PF14949.1 GAM25606.1 - 0.65 10.4 5.6 0.67 10.4 0.0 3.6 3 0 0 3 3 3 0 ARF7 effector protein C-terminus 2-ph_phosp PF04029.9 GAM25607.1 - 1.7e-63 213.7 0.1 2.3e-63 213.2 0.1 1.0 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase Pkinase PF00069.20 GAM25608.1 - 3e-67 226.4 0.0 4e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25608.1 - 1.4e-49 168.4 0.0 2.3e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM25608.1 - 3e-06 26.4 0.0 0.00021 20.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF1241 PF06840.6 GAM25608.1 - 1e-05 24.8 0.1 2.5e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Pkinase PF00069.20 GAM25609.1 - 3.8e-26 91.7 1.3 2.5e-21 76.0 0.3 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25609.1 - 1.7e-15 56.8 2.3 3e-12 46.1 0.4 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Cofilin_ADF PF00241.15 GAM25610.1 - 2.9e-37 127.3 1.1 3.1e-37 127.2 0.8 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RRM_1 PF00076.17 GAM25612.1 - 1.4e-27 95.1 0.5 1.5e-14 53.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25612.1 - 4.7e-20 71.1 2.5 7e-12 45.0 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25612.1 - 5.9e-17 61.4 0.3 1.9e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 GAM25612.1 - 2.8e-05 23.6 9.8 4.6e-05 23.0 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM25612.1 - 0.0021 18.0 9.5 0.0037 17.2 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM25612.1 - 0.024 14.2 9.5 0.052 13.2 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM25612.1 - 0.72 9.6 9.3 1.5 8.6 6.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 GAM25612.1 - 4.8 7.1 8.5 11 5.9 5.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Tau95 PF09734.4 GAM25613.1 - 3e-46 158.1 0.0 3e-46 158.1 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF883 PF05957.8 GAM25613.1 - 1 9.7 4.7 3 8.2 3.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF1162 PF06650.7 GAM25614.1 - 7.7e-45 153.2 0.6 2.6e-40 138.3 0.0 3.3 2 2 1 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM25614.1 - 8.4e-21 73.7 0.3 3.2e-20 71.8 0.2 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter CS PF04969.11 GAM25615.1 - 1.2e-08 35.3 0.7 1.8e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 CS domain Annexin PF00191.15 GAM25615.1 - 0.27 11.1 2.2 3.5 7.6 0.0 2.7 3 0 0 3 3 3 0 Annexin RAI16-like PF10257.4 GAM25616.1 - 4.5e-79 265.9 5.5 8.3e-79 265.0 3.8 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FPL PF09758.4 GAM25616.1 - 0.01 15.6 0.0 0.062 13.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein DUF2457 PF10446.4 GAM25616.1 - 0.044 12.5 6.5 0.11 11.2 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Zip PF02535.17 GAM25616.1 - 3.3 6.6 6.4 8.4 5.2 4.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Kelch_6 PF13964.1 GAM25617.1 - 4.4e-06 26.6 2.8 4.5e-05 23.4 0.0 3.2 3 1 1 4 4 4 1 Kelch motif Kelch_1 PF01344.20 GAM25617.1 - 1.5e-05 24.4 5.8 0.00027 20.3 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 GAM25617.1 - 0.00018 21.5 3.0 0.001 19.1 0.0 2.9 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM25617.1 - 0.0016 18.1 0.1 0.0016 18.1 0.0 4.1 5 1 1 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM25617.1 - 0.0028 17.3 0.5 0.12 12.1 0.0 3.2 2 1 1 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM25617.1 - 0.0031 17.4 0.4 0.13 12.2 0.0 3.0 3 1 0 3 3 3 1 Kelch motif FBA_1 PF07734.8 GAM25617.1 - 0.098 12.3 0.4 0.98 9.1 0.0 2.5 1 1 1 3 3 3 0 F-box associated Kelch_6 PF13964.1 GAM25618.1 - 1.1e-09 37.9 8.3 0.0048 17.0 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM25618.1 - 2.7e-06 27.0 13.2 0.00054 19.6 0.0 5.2 4 3 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25618.1 - 2.6e-05 24.2 6.7 0.12 12.5 0.0 5.5 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25618.1 - 8e-05 22.0 7.6 0.024 14.2 0.1 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM25618.1 - 0.0014 18.4 6.5 0.064 13.2 0.7 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 GAM25618.1 - 0.018 14.8 3.3 1 9.2 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 GAM25619.1 - 0.012 15.3 0.1 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM25619.1 - 0.028 14.3 0.2 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.1 GAM25619.1 - 0.08 13.1 0.5 0.37 11.0 0.2 1.9 1 1 1 2 2 2 0 Kelch motif Kelch_1 PF01344.20 GAM25619.1 - 0.61 9.6 2.4 1.2 8.7 1.3 1.9 2 1 0 2 2 2 0 Kelch motif Kelch_6 PF13964.1 GAM25620.1 - 0.0051 16.9 0.7 2.3 8.5 0.0 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.1 GAM25620.1 - 0.17 12.1 0.4 5.3 7.3 0.1 2.5 2 1 0 2 2 2 0 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM25622.1 - 1.6e-06 28.0 5.2 0.29 11.3 0.0 5.6 5 1 1 6 6 6 3 Kelch motif FliT PF05400.8 GAM25622.1 - 0.13 12.7 0.8 1.4 9.3 0.0 2.4 2 1 0 2 2 2 0 Flagellar protein FliT zf-B_box PF00643.19 GAM25623.1 - 2e-07 30.7 5.4 2e-07 30.7 3.7 1.9 2 0 0 2 2 2 1 B-box zinc finger Kelch_1 PF01344.20 GAM25623.1 - 0.0012 18.3 0.9 0.0042 16.6 0.1 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.1 GAM25623.1 - 0.0025 17.9 10.1 0.016 15.3 0.1 5.1 6 0 0 6 6 6 1 Kelch motif RTX PF02382.10 GAM25623.1 - 0.03 12.6 2.8 0.042 12.1 2.0 1.1 1 0 0 1 1 1 0 RTX N-terminal domain Kelch_2 PF07646.10 GAM25623.1 - 0.53 10.1 2.4 1.3 8.8 0.2 2.6 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 GAM25623.1 - 3.8 7.5 6.4 1.2 9.1 0.7 2.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 GAM25624.1 - 1.2e-11 44.1 5.3 1.9e-07 30.7 0.1 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM25624.1 - 4.8e-11 42.3 2.8 0.0024 17.9 0.0 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM25624.1 - 2.6e-07 30.6 0.7 0.00021 21.3 0.0 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25624.1 - 3.5e-06 26.4 10.5 6.4e-06 25.6 0.4 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM25624.1 - 1.9e-05 24.2 4.0 0.31 10.8 0.0 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 GAM25624.1 - 0.00053 19.8 6.5 0.085 12.8 0.3 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 GAM25625.1 - 2.2e-07 30.3 2.7 2.8e-06 26.7 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 GAM25625.1 - 3.7e-05 23.4 2.6 0.0011 18.6 0.0 3.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25625.1 - 7.5e-05 22.7 0.8 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM25625.1 - 0.0035 17.4 0.3 0.14 12.3 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM25625.1 - 0.034 14.1 1.5 0.19 11.7 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Peptidase_M16_C PF05193.16 GAM25627.1 - 2e-26 92.7 1.0 4.7e-26 91.5 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 GAM25627.1 - 1e-15 57.8 0.0 1.9e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-PARP PF00645.13 GAM25628.1 - 9.1e-22 77.1 0.6 5.1e-21 74.7 0.1 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.4 GAM25628.1 - 1.3e-11 44.0 1.5 1.3e-11 44.0 1.0 1.8 2 0 0 2 2 2 1 Zinc-finger (CX5CX6HX5H) motif UDG PF03167.14 GAM25628.1 - 0.0022 17.4 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FHA PF00498.21 GAM25628.1 - 0.0038 17.3 0.0 0.01 15.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain Ubie_methyltran PF01209.13 GAM25629.1 - 6.5e-91 303.5 0.0 8.3e-91 303.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 GAM25629.1 - 1.2e-13 51.3 0.0 6.1e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM25629.1 - 2e-10 40.4 0.0 6.5e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM25629.1 - 2.5e-10 40.6 0.0 5.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM25629.1 - 1.8e-06 27.7 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM25629.1 - 5e-06 26.9 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM25629.1 - 4.5e-05 23.9 0.0 0.0003 21.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 GAM25629.1 - 0.00091 18.9 0.0 0.0037 16.9 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase CST-I PF06002.7 GAM25629.1 - 0.05 12.8 0.0 6.2 6.0 0.0 2.1 2 0 0 2 2 2 0 Alpha-2,3-sialyltransferase (CST-I) PhyH PF05721.8 GAM25630.1 - 1.5e-07 31.6 0.0 1.9e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM25630.1 - 9.9e-06 24.2 0.3 0.065 11.7 0.1 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) DUF3439 PF11921.3 GAM25630.1 - 0.65 9.7 16.3 1.2 8.9 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FNIP PF05725.7 GAM25631.1 - 8.7e-12 44.8 4.4 0.0028 17.5 0.0 6.5 2 1 3 6 6 6 5 FNIP Repeat TIG PF01833.19 GAM25632.1 - 0.00072 19.4 5.1 0.00072 19.4 3.5 3.3 3 1 0 3 3 3 1 IPT/TIG domain EGF PF00008.22 GAM25632.1 - 0.0023 17.8 8.6 0.006 16.5 6.0 1.7 1 0 0 1 1 1 1 EGF-like domain DUF3827 PF12877.2 GAM25632.1 - 0.026 12.6 0.1 0.035 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) LRR19-TM PF15176.1 GAM25632.1 - 0.059 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EGF_2 PF07974.8 GAM25632.1 - 0.12 12.6 13.6 0.31 11.2 9.4 1.7 1 0 0 1 1 1 0 EGF-like domain SKG6 PF08693.5 GAM25632.1 - 9.4 5.6 14.1 0.028 13.7 2.1 2.5 3 0 0 3 3 3 0 Transmembrane alpha-helix domain LRR_1 PF00560.28 GAM25633.1 - 0.25 11.5 8.0 9.2 6.7 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 GAM25633.1 - 0.26 10.9 7.0 8 6.2 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) THUMP PF02926.12 GAM25634.1 - 2.6e-12 46.8 1.7 4.8e-12 45.9 1.1 1.4 1 0 0 1 1 1 1 THUMP domain SSP160 PF06933.6 GAM25634.1 - 0.00017 19.7 4.3 0.00023 19.2 3.0 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 GAM25634.1 - 0.07 13.1 8.8 4.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3439 PF11921.3 GAM25634.1 - 1.2 8.8 13.7 0.21 11.3 6.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EF-hand_1 PF00036.27 GAM25635.1 - 1.2e-15 55.5 8.2 8.7e-07 27.8 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAM25635.1 - 5.3e-15 53.8 6.1 1.1e-05 24.9 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 GAM25635.1 - 3.3e-14 52.2 2.9 9.6e-11 41.1 1.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 GAM25635.1 - 3e-13 49.7 3.9 1e-10 41.5 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM25635.1 - 2.5e-07 29.7 11.1 1.1e-05 24.5 0.3 3.2 3 0 0 3 3 3 2 EF hand Nop14 PF04147.7 GAM25635.1 - 0.0043 15.0 18.8 0.0066 14.4 13.0 1.2 1 0 0 1 1 1 1 Nop14-like family Herpes_UL32 PF06070.6 GAM25635.1 - 0.016 13.7 13.2 0.016 13.7 9.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 YL1 PF05764.8 GAM25635.1 - 0.046 13.3 17.9 0.07 12.7 12.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein NESP55 PF06390.7 GAM25635.1 - 0.056 12.8 8.6 0.079 12.3 6.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) CENP-T PF15511.1 GAM25635.1 - 0.077 12.2 12.7 0.063 12.5 8.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T FtsH_ext PF06480.10 GAM25635.1 - 0.079 13.1 6.8 0.25 11.5 4.7 2.0 1 1 0 1 1 1 0 FtsH Extracellular Mucin PF01456.12 GAM25635.1 - 0.094 12.4 17.6 0.14 11.9 12.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2457 PF10446.4 GAM25635.1 - 0.1 11.3 22.6 0.21 10.3 15.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Lin-8 PF03353.10 GAM25635.1 - 0.43 9.7 14.3 0.62 9.3 9.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pox_RNA_Pol_19 PF05320.7 GAM25635.1 - 0.64 9.7 13.8 1.6 8.4 9.6 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SDA1 PF05285.7 GAM25635.1 - 0.83 8.8 20.3 1.2 8.3 13.6 1.7 2 0 0 2 2 2 0 SDA1 Macoilin PF09726.4 GAM25635.1 - 1 7.5 14.5 1.2 7.3 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein TRAP_alpha PF03896.11 GAM25635.1 - 3.4 6.5 12.0 5.8 5.8 8.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hid1 PF12722.2 GAM25635.1 - 4 4.9 11.3 4.3 4.8 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 GAM25635.1 - 5.2 4.9 12.6 7.4 4.4 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM220 PF15487.1 GAM25635.1 - 5.3 6.3 12.7 8.1 5.7 8.8 1.3 1 0 0 1 1 1 0 FAM220 family Phosphodiest PF01663.17 GAM25636.1 - 6.8e-12 45.3 0.2 1.4e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 GAM25636.1 - 2.2e-06 27.0 0.2 4.6e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Sulfatase ATP_bind_1 PF03029.12 GAM25637.1 - 2.3e-68 230.2 0.7 2.8e-68 229.9 0.5 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 GAM25637.1 - 0.014 14.8 0.1 0.076 12.4 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GFA PF04828.9 GAM25638.1 - 2.8e-12 46.4 1.7 2.8e-12 46.4 1.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ank_2 PF12796.2 GAM25639.1 - 1.6e-12 47.6 0.6 0.0087 16.3 0.0 5.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM25639.1 - 5.5e-11 41.6 6.7 0.014 15.5 0.0 9.9 11 0 0 11 11 11 1 Ankyrin repeat Ank_5 PF13857.1 GAM25639.1 - 6.2e-08 32.6 1.2 0.089 13.0 0.0 5.8 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM25639.1 - 4.7e-05 23.7 2.4 0.27 11.7 0.0 4.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM25639.1 - 0.00098 18.8 1.8 0.87 9.5 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.3 GAM25639.1 - 0.27 11.0 3.6 1.1 9.1 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) EGF_2 PF07974.8 GAM25640.1 - 0.013 15.6 5.4 0.037 14.2 3.7 1.8 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM25640.1 - 0.098 12.6 4.6 0.24 11.4 3.2 1.6 1 0 0 1 1 1 0 EGF-like domain Lectin_C PF00059.16 GAM25641.1 - 4.4e-05 24.0 0.4 0.00011 22.7 0.0 2.0 2 0 0 2 2 2 1 Lectin C-type domain DUF749 PF05370.6 GAM25641.1 - 0.035 14.0 1.0 0.89 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF749) CCDC84 PF14968.1 GAM25641.1 - 0.051 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 DNA_ligase_A_C PF04679.10 GAM25642.1 - 6e-27 93.8 0.0 7.6e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 GAM25642.1 - 1.1e-05 25.0 0.4 0.0043 16.7 0.0 2.2 2 0 0 2 2 2 2 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 GAM25643.1 - 3.5e-54 183.2 0.0 3.5e-54 183.2 0.0 2.9 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 GAM25643.1 - 5.5e-51 172.8 0.5 1.2e-50 171.8 0.4 1.6 1 0 0 1 1 1 1 DNA ligase N terminus Merozoite_SPAM PF07133.6 GAM25643.1 - 0.00046 20.1 40.7 0.0081 16.0 9.2 2.5 2 0 0 2 2 2 2 Merozoite surface protein (SPAM) MIP-T3 PF10243.4 GAM25643.1 - 0.63 8.4 55.5 0.92 7.9 38.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 GAM25643.1 - 0.63 7.8 46.6 0.72 7.7 17.9 2.2 2 0 0 2 2 2 0 Nop14-like family RRM_1 PF00076.17 GAM25644.1 - 6.5e-30 102.5 0.0 1e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25644.1 - 3.9e-19 68.3 0.0 2.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25644.1 - 9.1e-16 57.4 0.0 6.6e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 GAM25644.1 - 0.075 12.5 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain zf-CDGSH PF09360.5 GAM25645.1 - 1.8e-24 85.2 4.4 1.2e-11 44.1 0.1 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type zf-RING_4 PF14570.1 GAM25645.1 - 0.089 12.3 2.1 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4505 PF14956.1 GAM25645.1 - 0.13 11.9 2.4 0.28 10.7 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4505) Metallothio_Euk PF12749.2 GAM25645.1 - 0.19 11.8 1.6 5.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic metallothionein PH PF00169.24 GAM25646.1 - 6.7e-28 96.9 5.7 9.9e-15 54.6 0.3 2.4 2 0 0 2 2 2 2 PH domain FHA PF00498.21 GAM25646.1 - 7.2e-16 58.0 0.3 2.1e-15 56.6 0.2 1.8 1 0 0 1 1 1 1 FHA domain PH_11 PF15413.1 GAM25646.1 - 6.8e-09 35.9 14.7 7.6e-05 22.9 0.4 4.3 3 2 1 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.1 GAM25646.1 - 4e-06 26.8 3.5 0.0093 16.0 1.3 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 GAM25646.1 - 0.0013 18.9 4.2 1.2 9.3 0.1 4.1 3 2 1 4 4 4 1 Pleckstrin homology domain bPH_3 PF14470.1 GAM25646.1 - 0.27 11.5 2.6 14 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial PH domain LRR_6 PF13516.1 GAM25647.1 - 4.8e-20 69.3 28.7 0.16 12.1 0.0 16.6 16 1 1 17 17 17 6 Leucine Rich repeat IstB_IS21 PF01695.12 GAM25647.1 - 0.0062 15.9 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 GAM25647.1 - 0.0086 16.3 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 GAM25647.1 - 0.04 13.3 0.2 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 GAM25647.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Ste50p-SAM PF09235.5 GAM25647.1 - 0.18 11.8 4.8 34 4.5 0.1 4.6 3 1 1 4 4 4 0 Ste50p, sterile alpha motif LRR_1 PF00560.28 GAM25647.1 - 9 6.7 38.7 23 5.5 0.4 12.8 11 6 1 12 12 12 0 Leucine Rich Repeat Guanylate_kin PF00625.16 GAM25648.1 - 5e-57 192.3 0.0 5.9e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 GAM25648.1 - 6.5e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM25648.1 - 3.4e-05 24.6 0.1 5.9e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM25648.1 - 4.6e-05 23.3 0.0 9.2e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM25648.1 - 0.00021 20.5 0.0 0.00065 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 GAM25648.1 - 0.0038 17.1 0.0 0.007 16.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM25648.1 - 0.0054 16.7 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 GAM25648.1 - 0.0063 16.8 0.3 0.016 15.5 0.2 1.9 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 GAM25648.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM25648.1 - 0.017 14.2 0.1 0.052 12.6 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 GAM25648.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 GAM25648.1 - 0.018 15.1 0.0 0.059 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 GAM25648.1 - 0.026 14.0 0.1 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.12 GAM25648.1 - 0.034 13.5 0.2 5.8 6.2 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_29 PF13555.1 GAM25648.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 GAM25648.1 - 0.06 12.7 0.2 0.19 11.1 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ADK PF00406.17 GAM25648.1 - 0.07 13.0 0.2 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase KAP_NTPase PF07693.9 GAM25648.1 - 0.086 11.8 0.0 0.087 11.7 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain RNA_helicase PF00910.17 GAM25648.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Foie-gras_1 PF11817.3 GAM25649.1 - 1.8e-12 47.2 2.8 5.7e-11 42.3 1.9 2.6 1 1 0 1 1 1 1 Foie gras liver health family 1 TRAPPC10 PF12584.3 GAM25649.1 - 4.5e-09 35.9 0.0 1.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Serglycin PF04360.7 GAM25649.1 - 0.03 14.0 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Serglycin DUF4602 PF15375.1 GAM25650.1 - 5.1e-06 26.6 11.7 5.1e-06 26.6 8.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) Exo_endo_phos PF03372.18 GAM25651.1 - 1.3e-14 54.7 0.0 1.7e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM49 PF09478.5 GAM25652.1 - 7.3e-07 29.2 2.2 1.6e-06 28.0 1.5 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF4497 PF14924.1 GAM25652.1 - 0.37 11.1 2.3 0.66 10.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) Sds3 PF08598.6 GAM25652.1 - 0.97 8.9 9.3 1.2 8.6 5.9 1.5 1 1 0 1 1 1 0 Sds3-like DUF2312 PF10073.4 GAM25652.1 - 6.4 6.2 7.7 6.9 6.0 1.7 3.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) SPACA7 PF15307.1 GAM25652.1 - 9.3 6.4 14.6 3.1 7.9 5.6 2.8 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 DUF4238 PF14022.1 GAM25653.1 - 0.0043 16.3 2.9 0.0049 16.1 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) PhaP_Bmeg PF09602.5 GAM25653.1 - 0.033 14.0 2.1 0.054 13.3 1.4 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CBM49 PF09478.5 GAM25653.1 - 0.045 13.8 0.8 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 DUF3540 PF12059.3 GAM25653.1 - 0.41 10.2 9.9 0.11 12.1 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) STAT_alpha PF01017.15 GAM25653.1 - 0.49 10.0 9.2 0.12 12.0 0.7 2.2 1 1 1 2 2 2 0 STAT protein, all-alpha domain APG6 PF04111.7 GAM25653.1 - 0.65 8.9 13.1 0.16 11.0 2.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Uso1_p115_C PF04871.8 GAM25653.1 - 1.8 8.4 8.1 8.2 6.3 5.5 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ERM PF00769.14 GAM25653.1 - 3.2 7.2 20.0 0.73 9.3 7.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2312 PF10073.4 GAM25653.1 - 6.3 6.2 10.9 7.3 6.0 0.6 3.9 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF972 PF06156.8 GAM25653.1 - 9.5 6.6 8.2 17 5.8 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kelch_6 PF13964.1 GAM25654.1 - 4.5e-07 29.7 13.9 0.0044 17.1 0.1 6.0 4 2 2 6 6 6 3 Kelch motif Kelch_4 PF13418.1 GAM25654.1 - 9.7e-07 28.4 4.1 0.0029 17.3 0.0 4.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25654.1 - 0.0013 18.8 7.1 0.0098 16.0 0.0 4.0 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25654.1 - 0.0014 18.1 0.2 0.0014 18.1 0.2 4.7 5 1 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 GAM25654.1 - 0.2 11.4 10.4 1.9 8.3 0.0 4.6 4 1 1 5 5 5 0 Kelch motif ATG_C PF09333.6 GAM25655.1 - 5.1e-13 49.0 0.0 1.4e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 GAM25655.1 - 1.7e-06 27.5 0.2 5.7e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Atg14 PF10186.4 GAM25656.1 - 0.0035 16.3 0.9 0.0057 15.6 0.4 1.5 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4279 PF14106.1 GAM25656.1 - 0.01 15.6 0.3 0.32 10.8 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) FlgN PF05130.7 GAM25656.1 - 0.077 13.2 0.9 4.5 7.5 0.1 2.8 3 0 0 3 3 3 0 FlgN protein DUF4132 PF13569.1 GAM25656.1 - 0.089 12.3 0.1 3.5 7.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4132) SlyX PF04102.7 GAM25656.1 - 0.2 12.0 3.0 0.67 10.3 0.3 2.8 3 0 0 3 3 3 0 SlyX FAM150 PF15129.1 GAM25656.1 - 0.25 11.2 1.9 0.49 10.2 0.0 2.1 2 1 1 3 3 3 0 FAM150 family MOR2-PAG1_N PF14222.1 GAM25656.1 - 0.45 9.1 7.8 0.86 8.2 5.3 1.5 1 1 0 1 1 1 0 Cell morphogenesis N-terminal DUF948 PF06103.6 GAM25656.1 - 0.49 10.2 4.6 2.5 8.0 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Transposase_22 PF02994.9 GAM25656.1 - 0.65 8.4 3.5 1.4 7.3 0.3 2.2 2 0 0 2 2 2 0 L1 transposable element UPF0118 PF01594.11 GAM25656.1 - 1.1 8.1 3.0 13 4.6 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF20 Fzo_mitofusin PF04799.8 GAM25656.1 - 2.9 7.2 6.5 3.7 6.8 0.2 2.7 3 0 0 3 3 3 0 fzo-like conserved region Pep_deformylase PF01327.16 GAM25657.1 - 0.081 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Polypeptide deformylase YEATS PF03366.11 GAM25658.1 - 1.5e-12 47.0 0.8 1.2e-06 28.0 0.1 3.3 1 1 1 2 2 2 2 YEATS family ADIP PF11559.3 GAM25660.1 - 0.0053 16.6 1.5 0.0053 16.6 1.0 2.2 2 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding BRCT PF00533.21 GAM25662.1 - 8.9e-07 28.9 0.2 0.045 13.9 0.0 2.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain HCaRG PF07258.9 GAM25663.1 - 3.3e-31 108.2 9.4 3.7e-31 108.0 6.5 1.0 1 0 0 1 1 1 1 HCaRG protein Symplekin_C PF12295.3 GAM25663.1 - 0.012 15.5 0.6 0.023 14.6 0.4 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal BTB PF00651.26 GAM25664.1 - 2.5e-24 85.4 0.0 5.3e-23 81.1 0.0 2.6 1 1 1 2 2 2 1 BTB/POZ domain HEAT PF02985.17 GAM25664.1 - 0.00021 21.1 0.0 0.47 10.6 0.0 3.7 3 1 1 4 4 4 2 HEAT repeat BACK PF07707.10 GAM25664.1 - 0.005 16.6 0.1 0.09 12.6 0.0 2.8 3 0 0 3 3 3 1 BTB And C-terminal Kelch Cnd1 PF12717.2 GAM25664.1 - 0.0053 16.6 0.1 0.41 10.4 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 GAM25664.1 - 0.0085 15.2 0.5 0.034 13.2 0.3 1.9 1 1 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 GAM25664.1 - 1.3 9.0 7.4 1.4 8.9 0.6 4.0 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat Methyltransf_28 PF02636.12 GAM25665.1 - 1.1e-36 126.5 0.0 1.8e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 GAM25665.1 - 0.042 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_11 PF13414.1 GAM25667.1 - 5.7e-30 102.7 5.5 6.2e-08 32.1 0.0 5.1 4 1 0 4 4 4 4 TPR repeat TPR_16 PF13432.1 GAM25667.1 - 9.6e-28 96.2 0.0 3e-06 27.7 0.0 4.4 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 GAM25667.1 - 1.1e-27 93.6 1.8 2.3e-05 23.9 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 GAM25667.1 - 4.3e-27 92.5 3.1 1e-06 28.1 0.0 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 GAM25667.1 - 1.3e-23 82.6 3.6 1.3e-07 31.4 0.0 5.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM25667.1 - 2.2e-21 75.9 3.3 1.3e-06 28.6 0.0 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM25667.1 - 2.1e-19 68.2 0.3 0.0031 18.0 0.0 7.6 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM25667.1 - 4.1e-18 64.0 1.2 0.015 15.4 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM25667.1 - 4.3e-18 63.6 0.5 0.00073 19.1 0.0 6.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 GAM25667.1 - 7.2e-18 62.9 3.7 0.00044 19.8 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM25667.1 - 9.8e-17 60.8 2.5 2e-05 24.6 0.0 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM25667.1 - 8.4e-10 38.4 5.1 0.074 13.5 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 GAM25667.1 - 1.7e-09 37.4 0.8 0.0028 17.4 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 GAM25667.1 - 1.7e-08 34.0 2.1 0.029 14.3 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM25667.1 - 2.2e-06 27.4 0.8 0.22 11.4 0.0 4.2 3 1 1 4 4 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 GAM25667.1 - 1.9e-05 24.6 2.1 0.94 9.4 0.0 4.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 GAM25667.1 - 4.1e-05 22.7 0.5 0.0027 16.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 GAM25667.1 - 0.00081 18.5 0.2 0.052 12.7 0.0 3.5 4 0 0 4 4 4 1 SHNi-TPR BTAD PF03704.12 GAM25667.1 - 0.003 17.8 2.1 0.18 12.0 0.2 3.2 2 1 0 3 3 3 1 Bacterial transcriptional activator domain DUF3530 PF12048.3 GAM25667.1 - 0.018 14.0 0.0 0.018 14.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) TPR_5 PF12688.2 GAM25667.1 - 0.081 12.9 0.1 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratrico peptide repeat DUF572 PF04502.8 GAM25668.1 - 0.32 10.1 14.3 0.51 9.5 9.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-B_dimeris PF09026.5 GAM25668.1 - 3.1 8.1 13.6 3.7 7.8 2.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RepB-RCR_reg PF10723.4 GAM25668.1 - 4 7.2 7.7 11 5.8 5.4 1.8 1 0 0 1 1 1 0 Replication regulatory protein RepB MAS20 PF02064.10 GAM25668.1 - 4.3 7.2 8.1 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 MAS20 protein import receptor Nucleoplasmin PF03066.10 GAM25668.1 - 4.6 6.7 15.2 0.19 11.2 1.0 2.4 2 0 0 2 2 2 0 Nucleoplasmin DUF3810 PF12725.2 GAM25669.1 - 0.025 13.4 3.0 0.032 13.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) TPD52 PF04201.10 GAM25669.1 - 0.092 12.4 2.1 0.11 12.2 1.4 1.3 1 1 0 1 1 1 0 Tumour protein D52 family Siah-Interact_N PF09032.6 GAM25669.1 - 1 9.4 6.7 4.5 7.3 4.6 2.0 1 1 0 1 1 1 0 Siah interacting protein, N terminal TMF_TATA_bd PF12325.3 GAM25669.1 - 2.4 7.9 10.4 17 5.1 5.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pkinase_Tyr PF07714.12 GAM25670.1 - 1.3e-98 329.2 0.0 2.3e-61 207.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 GAM25670.1 - 1.5e-86 289.7 0.0 6.1e-49 166.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 GAM25670.1 - 0.067 12.9 0.0 3.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RRM_3 PF08777.6 GAM25671.1 - 1.7e-05 24.6 0.3 1.7e-05 24.6 0.2 2.5 1 1 2 3 3 3 1 RNA binding motif DUF1168 PF06658.7 GAM25671.1 - 0.00079 18.9 11.4 0.0012 18.3 7.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) La PF05383.12 GAM25672.1 - 1.9e-18 65.9 0.7 4.2e-18 64.8 0.5 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 GAM25672.1 - 1.6e-12 46.8 0.2 8.9e-12 44.4 0.0 2.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM25672.1 - 3.9e-10 39.5 0.0 1.1e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM25672.1 - 0.00017 21.3 0.0 0.00045 20.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dfp1_Him1_M PF08630.5 GAM25672.1 - 0.0024 17.6 0.4 0.0037 17.0 0.3 1.3 1 0 0 1 1 1 1 Dfp1/Him1, central region UEV PF05743.8 GAM25672.1 - 0.1 12.3 0.4 1.8 8.2 0.0 2.6 2 1 0 2 2 2 0 UEV domain Mur_ligase_M PF08245.7 GAM25673.1 - 6.8e-07 29.5 0.6 2.2e-05 24.6 0.4 2.9 1 1 0 1 1 1 1 Mur ligase middle domain SNF2_N PF00176.18 GAM25674.1 - 2.1e-73 246.7 2.4 2.1e-73 246.7 1.6 3.1 3 1 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.1 GAM25674.1 - 8e-46 155.5 18.8 8e-46 155.5 13.0 6.2 5 1 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 GAM25674.1 - 5.2e-14 51.8 0.1 2.7e-13 49.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Spectrin PF00435.16 GAM25675.1 - 0.0063 16.7 0.2 0.011 15.9 0.1 1.5 1 1 0 1 1 1 1 Spectrin repeat Snapin_Pallidin PF14712.1 GAM25675.1 - 0.0088 16.3 0.4 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 Snapin/Pallidin Glyco_tran_WecB PF03808.8 GAM25675.1 - 0.028 13.8 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family ADIP PF11559.3 GAM25675.1 - 0.045 13.6 0.8 0.069 13.0 0.5 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3597 PF12200.3 GAM25675.1 - 0.15 12.4 0.5 0.26 11.6 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) EF-hand_2 PF09068.6 GAM25676.1 - 0.0063 16.5 0.9 0.016 15.2 0.4 1.8 1 1 1 2 2 2 1 EF hand DUF2935 PF11155.3 GAM25676.1 - 0.015 15.4 2.2 0.038 14.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF948 PF06103.6 GAM25676.1 - 0.051 13.4 2.6 1.7 8.5 1.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SLT_2 PF13406.1 GAM25676.1 - 0.097 11.5 2.6 0.25 10.2 0.4 2.2 2 1 0 2 2 2 0 Transglycosylase SLT domain TerB PF05099.8 GAM25676.1 - 0.1 12.3 1.4 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TerB Flagellin_C PF00700.16 GAM25676.1 - 0.41 10.8 3.1 1.3 9.2 1.5 2.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region LNP1 PF15419.1 GAM25677.1 - 0.012 15.7 8.6 0.012 15.7 5.9 1.8 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 SNF2_N PF00176.18 GAM25678.1 - 2.7e-63 213.5 7.9 6.5e-63 212.2 5.4 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM25678.1 - 2e-15 56.4 0.0 5.5e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Epiglycanin_C PF14654.1 GAM25679.1 - 0.031 14.2 2.3 0.08 12.9 0.2 2.3 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region C2 PF00168.25 GAM25680.1 - 1.3e-15 56.9 0.1 2.4e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain DUF2625 PF10946.3 GAM25680.1 - 0.0015 17.4 0.1 0.3 10.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF2625 RE_NgoFVII PF09565.5 GAM25680.1 - 0.043 12.7 0.1 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 NgoFVII restriction endonuclease DUF290 PF01060.18 GAM25680.1 - 0.054 13.5 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Transthyretin-like family ECR1_N PF14382.1 GAM25681.1 - 2.8e-09 36.1 0.0 5.2e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pyr_redox_dim PF02852.17 GAM25682.1 - 3e-38 130.2 0.2 1e-37 128.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 GAM25682.1 - 8.3e-38 130.2 19.0 1.7e-37 129.3 12.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM25682.1 - 3.6e-22 78.5 16.8 1.1e-19 70.6 1.3 3.7 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM25682.1 - 3.3e-12 46.8 2.6 1.2e-06 28.7 0.4 2.6 2 1 1 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM25682.1 - 1.5e-10 40.7 4.2 1.3e-08 34.3 1.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM25682.1 - 1.2e-06 27.6 1.0 1.2e-06 27.6 0.7 4.0 2 1 2 4 4 4 1 FAD binding domain HI0933_like PF03486.9 GAM25682.1 - 1.7e-06 26.8 12.7 2.1e-05 23.1 0.3 3.5 3 1 1 4 4 4 2 HI0933-like protein GIDA PF01134.17 GAM25682.1 - 4e-06 25.9 0.9 4e-06 25.9 0.6 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 GAM25682.1 - 1.1e-05 25.3 6.1 0.00018 21.4 1.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 GAM25682.1 - 0.00015 20.8 5.1 0.0023 16.8 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 GAM25682.1 - 0.00023 20.3 4.1 0.015 14.3 0.1 3.0 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 GAM25682.1 - 0.00033 19.8 0.6 0.00033 19.8 0.4 3.0 2 1 1 3 3 3 1 Thi4 family 3HCDH_N PF02737.13 GAM25682.1 - 0.0035 17.0 0.5 0.0035 17.0 0.3 2.5 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 GAM25682.1 - 0.0042 16.0 2.8 0.7 8.7 0.0 2.6 2 1 0 3 3 3 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 GAM25682.1 - 0.0046 16.5 4.0 0.41 10.1 0.2 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 GAM25682.1 - 0.005 15.8 22.2 0.023 13.6 1.0 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM25682.1 - 0.013 14.5 13.1 0.018 14.0 1.9 3.0 2 1 0 2 2 2 0 FAD binding domain XdhC_C PF13478.1 GAM25682.1 - 0.031 14.5 0.0 6.8 7.0 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 GAM25682.1 - 0.073 13.3 1.4 3 8.1 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Mqo PF06039.10 GAM25682.1 - 0.15 10.2 3.2 0.22 9.6 0.3 2.3 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Jun PF03957.8 GAM25682.1 - 0.2 11.3 0.7 0.79 9.4 0.2 2.0 2 0 0 2 2 2 0 Jun-like transcription factor Endotoxin_N PF03945.9 GAM25683.1 - 4.7e-14 52.3 0.9 5.5e-06 25.9 0.0 2.4 1 1 1 2 2 2 2 delta endotoxin, N-terminal domain Orthopox_F6 PF06601.7 GAM25683.1 - 0.18 11.7 3.7 35 4.4 0.0 3.9 4 0 0 4 4 4 0 Orthopoxvirus F6 protein ABC2_membrane PF01061.19 GAM25684.1 - 2.5e-35 121.5 27.0 4.3e-35 120.7 18.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 GAM25684.1 - 1.5e-29 103.0 0.3 2.8e-29 102.1 0.0 1.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 GAM25684.1 - 5.3e-11 43.0 0.0 1.4e-05 25.2 0.0 2.5 1 1 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAM25684.1 - 9.3e-05 21.6 25.9 9.3e-05 21.6 16.5 2.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 GAM25684.1 - 0.00014 21.3 0.0 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 GAM25684.1 - 0.00026 20.2 0.1 0.00045 19.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM25684.1 - 0.00054 19.4 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 GAM25684.1 - 0.00059 19.9 0.0 0.002 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 GAM25684.1 - 0.00069 18.9 0.0 0.012 14.8 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 GAM25684.1 - 0.0013 19.5 0.0 0.0026 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM25684.1 - 0.0014 18.9 0.1 0.0047 17.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain PDR_CDR PF06422.7 GAM25684.1 - 0.0028 17.2 0.4 0.0028 17.2 0.3 1.8 2 0 0 2 2 1 1 CDR ABC transporter AAA_19 PF13245.1 GAM25684.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 GAM25684.1 - 0.0082 15.0 0.1 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 GAM25684.1 - 0.0085 15.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.1 GAM25684.1 - 0.0091 15.9 0.0 0.022 14.7 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain DUF3980 PF13140.1 GAM25684.1 - 0.012 15.8 0.9 0.038 14.2 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) AAA_28 PF13521.1 GAM25684.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 GAM25684.1 - 0.017 13.8 0.1 0.027 13.2 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_15 PF13175.1 GAM25684.1 - 0.021 13.8 0.6 1.1 8.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.10 GAM25684.1 - 0.028 13.0 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 GAM25684.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM25684.1 - 0.03 13.9 0.1 0.07 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 GAM25684.1 - 0.033 14.1 0.0 0.17 11.8 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_35 PF14516.1 GAM25684.1 - 0.037 12.6 0.0 0.064 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 GAM25684.1 - 0.047 14.0 0.9 0.076 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 GAM25684.1 - 0.062 13.4 0.1 0.72 10.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 GAM25684.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 GAM25684.1 - 0.088 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 GAM25684.1 - 0.1 12.8 0.1 0.25 11.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAM25684.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.12 GAM25684.1 - 0.11 11.9 0.1 0.59 9.4 0.0 2.3 3 0 0 3 3 3 0 Thymidylate kinase AAA_33 PF13671.1 GAM25684.1 - 0.15 11.9 0.1 0.34 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain NUDIX PF00293.23 GAM25686.1 - 1.6e-17 63.3 0.0 2.9e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pox_A_type_inc PF04508.7 GAM25687.1 - 0.011 15.4 1.2 0.029 14.1 0.8 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4200 PF13863.1 GAM25687.1 - 0.017 15.0 1.2 0.017 15.0 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.10 GAM25687.1 - 0.024 14.4 2.9 0.058 13.2 2.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Uds1 PF15456.1 GAM25687.1 - 0.33 10.9 3.1 0.34 10.9 0.2 2.3 2 0 0 2 2 2 0 Up-regulated During Septation TMF_DNA_bd PF12329.3 GAM25687.1 - 0.53 10.1 4.9 0.1 12.4 0.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TFIIB PF00382.14 GAM25688.1 - 4.2e-25 87.3 0.0 4.5e-13 48.8 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 GAM25688.1 - 4.7e-08 33.1 3.9 4.7e-08 33.1 2.7 3.5 2 1 0 2 2 2 1 Brf1-like TBP-binding domain RRN7 PF11781.3 GAM25688.1 - 9.4e-07 28.2 0.6 2e-06 27.2 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 GAM25688.1 - 6.3e-05 22.2 1.5 0.00016 20.9 1.0 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIF_alpha PF05793.7 GAM25688.1 - 0.0016 16.9 25.7 0.0031 15.9 17.8 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) A2L_zn_ribbon PF08792.5 GAM25688.1 - 0.013 14.9 2.7 0.028 13.8 1.9 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain Cyclin_N PF00134.18 GAM25688.1 - 0.047 13.2 0.1 0.56 9.7 0.0 2.4 2 0 0 2 2 2 0 Cyclin, N-terminal domain Urease_gamma PF00547.13 GAM25688.1 - 0.099 12.6 0.2 0.61 10.1 0.1 2.2 2 0 0 2 2 2 0 Urease, gamma subunit E1-E2_ATPase PF00122.15 GAM25690.1 - 1.3e-50 171.5 6.3 1.3e-50 171.5 4.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM25690.1 - 3.6e-37 127.6 8.4 3.6e-37 127.6 5.8 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM25690.1 - 3.3e-32 112.6 0.0 1.3e-31 110.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM25690.1 - 2.6e-19 68.9 0.0 5.6e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM25690.1 - 1.1e-14 55.0 0.1 3.9e-14 53.2 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM25690.1 - 0.00067 19.3 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM25691.1 - 1.3e-09 37.4 0.0 2.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2910 PF11139.3 GAM25691.1 - 0.079 12.0 0.3 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Ras PF00071.17 GAM25692.1 - 1.3e-50 170.9 0.0 1.6e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM25692.1 - 1.4e-16 61.0 0.0 1.9e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM25692.1 - 6.9e-07 28.6 0.0 9.7e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM25692.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase LRR_4 PF12799.2 GAM25693.1 - 3.6e-14 51.9 33.4 2.5e-08 33.3 3.3 4.5 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM25693.1 - 2e-11 43.4 26.6 5e-09 35.7 4.6 3.7 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 GAM25693.1 - 1.5e-05 24.3 28.4 0.3 11.2 0.1 6.9 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM25693.1 - 0.00016 21.2 21.0 0.4 11.0 0.1 7.2 7 0 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 GAM25693.1 - 0.0005 19.6 6.3 0.1 12.1 1.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 GAM25693.1 - 0.002 17.9 19.5 4.7 7.5 0.2 6.3 4 1 2 6 6 6 3 Leucine Rich repeat HSBP1 PF06825.7 GAM25693.1 - 0.12 11.9 1.2 4 7.0 0.0 2.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 3Beta_HSD PF01073.14 GAM25694.1 - 1.3e-36 125.7 0.0 1.6e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM25694.1 - 1.5e-29 103.1 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM25694.1 - 8.5e-18 64.1 0.2 6.5e-13 48.1 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM25694.1 - 5.9e-14 52.4 0.0 7.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM25694.1 - 2.3e-11 43.1 0.4 1.1e-09 37.6 0.2 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAM25694.1 - 2.1e-10 39.9 0.0 2.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 GAM25694.1 - 4.3e-06 26.1 0.0 8.3e-06 25.2 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 GAM25694.1 - 6.9e-05 22.8 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 GAM25694.1 - 0.0036 16.3 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 GAM25694.1 - 0.042 13.5 0.3 0.33 10.5 0.2 2.2 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.12 GAM25694.1 - 0.046 14.1 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 GAM25694.1 - 0.052 13.5 0.1 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 GAM25694.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Serglycin PF04360.7 GAM25695.1 - 3.6 7.2 13.4 1.6 8.4 2.0 3.0 2 0 0 2 2 2 0 Serglycin Dehalogenase PF13486.1 GAM25696.1 - 0.18 11.2 3.4 0.079 12.4 0.7 1.5 2 0 0 2 2 2 0 Reductive dehalogenase subunit DUF1829 PF08862.5 GAM25696.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.6 3 1 0 3 3 3 0 Domain of unknown function DUF1829 DUF3439 PF11921.3 GAM25696.1 - 2.3 7.9 10.1 0.53 10.0 4.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) TFIIF_alpha PF05793.7 GAM25697.1 - 0.011 14.1 12.5 0.016 13.5 8.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3632 PF12311.3 GAM25697.1 - 0.06 13.1 0.8 0.089 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) DUF2457 PF10446.4 GAM25697.1 - 0.11 11.1 21.0 0.17 10.5 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 GAM25697.1 - 5.5 5.9 13.3 10 5.0 9.2 1.4 1 0 0 1 1 1 0 BUD22 DUF2410 PF10307.4 GAM25698.1 - 1.1e-48 165.1 0.0 1.4e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Lactococcin PF04369.8 GAM25698.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family Myticin-prepro PF10690.4 GAM25699.1 - 0.00085 19.3 0.1 0.0012 18.7 0.1 1.2 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel TFIIIC_sub6 PF10419.4 GAM25700.1 - 1.8e-13 49.7 0.0 2.9e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit DUF1390 PF07150.6 GAM25700.1 - 0.056 12.7 4.5 0.12 11.7 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF1675 PF07897.6 GAM25700.1 - 4.8 6.9 26.4 1 9.1 12.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) AMPKBI PF04739.10 GAM25701.1 - 3e-23 81.5 1.3 3e-23 81.5 0.9 2.8 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain TFIIA PF03153.8 GAM25701.1 - 0.12 12.2 8.8 0.13 12.0 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 GAM25701.1 - 2.5 6.4 14.2 3.5 5.9 9.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PIH1 PF08190.7 GAM25701.1 - 4.3 6.6 10.3 5.9 6.2 7.2 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 GFA PF04828.9 GAM25702.1 - 2e-07 30.8 0.3 2e-07 30.8 0.2 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 GAM25702.1 - 0.56 10.1 6.3 0.62 10.0 3.1 1.9 2 0 0 2 2 2 0 Cysteine-rich CWC zf-C2H2_3 PF13878.1 GAM25702.1 - 0.59 9.7 6.8 3 7.4 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-CSL PF05207.8 GAM25702.1 - 0.68 9.4 7.5 0.33 10.4 2.7 2.0 2 0 0 2 2 2 0 CSL zinc finger EPTP PF03736.12 GAM25703.1 - 0.11 12.2 0.2 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 EPTP domain DPBB_1 PF03330.13 GAM25704.1 - 1.5e-09 37.7 1.7 3.8e-09 36.4 0.1 2.3 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAM25704.1 - 0.0031 17.5 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 Cerato-platanin Pollen_allerg_1 PF01357.16 GAM25704.1 - 0.0084 15.8 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen DPBB_1 PF03330.13 GAM25705.1 - 2.1e-08 34.0 0.3 5.5e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAM25705.1 - 0.0012 18.8 0.9 0.0026 17.7 0.6 1.5 1 1 0 1 1 1 1 Cerato-platanin Mfp-3 PF04202.8 GAM25705.1 - 0.056 13.6 1.4 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Foot protein 3 Trypan_PARP PF05887.6 GAM25705.1 - 7.9 6.2 11.3 15 5.4 7.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-RING_2 PF13639.1 GAM25707.1 - 9.8e-14 50.9 7.8 1.5e-13 50.2 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM25707.1 - 1.9e-10 40.7 4.4 3.8e-10 39.7 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 GAM25707.1 - 2.5e-08 33.4 8.2 4.2e-08 32.7 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM25707.1 - 9.1e-08 32.0 6.1 1.4e-07 31.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM25707.1 - 5.6e-07 29.1 4.1 8.1e-07 28.6 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM25707.1 - 4.3e-06 26.3 6.9 6.9e-06 25.6 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 GAM25707.1 - 0.0005 19.8 5.1 0.0014 18.4 3.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAM25707.1 - 0.00074 19.1 3.9 0.0021 17.7 2.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 GAM25707.1 - 0.001 18.5 5.1 0.0017 17.8 3.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 GAM25707.1 - 0.0036 17.2 8.4 0.014 15.3 5.8 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain DUF770 PF05591.7 GAM25707.1 - 0.0042 16.6 1.6 0.0061 16.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF770) Baculo_RING PF05883.6 GAM25707.1 - 0.0052 16.6 4.4 0.0052 16.6 3.1 1.7 2 0 0 2 2 2 1 Baculovirus U-box/Ring-like domain Cbl_N PF02262.11 GAM25707.1 - 0.01 15.5 0.4 0.017 14.8 0.3 1.3 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 RINGv PF12906.2 GAM25707.1 - 0.011 15.7 7.3 0.02 14.8 5.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 GAM25707.1 - 0.097 12.6 3.1 0.2 11.6 2.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-P11 PF03854.9 GAM25707.1 - 0.14 11.6 6.9 0.55 9.7 4.8 2.0 1 1 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.3 GAM25707.1 - 0.32 10.5 4.0 0.62 9.6 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 GAM25707.1 - 0.51 10.0 6.9 0.92 9.2 4.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 GAM25707.1 - 1.2 9.1 5.7 2.3 8.1 3.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 GAM25707.1 - 2.1 8.4 9.0 0.17 11.8 3.0 1.6 2 0 0 2 2 1 0 RING-like domain DUF1765 PF08578.5 GAM25708.1 - 3.3e-23 82.0 3.0 3.3e-23 82.0 2.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Sep15_SelM PF08806.6 GAM25709.1 - 1.5e-08 34.2 0.0 1.6e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Sep15/SelM redox domain ACC_central PF08326.7 GAM25711.1 - 6.1e-167 556.8 0.3 8.5e-167 556.3 0.2 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 GAM25711.1 - 2.8e-154 514.1 0.0 4.1e-154 513.5 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 GAM25711.1 - 1.3e-51 174.8 0.0 2.6e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 GAM25711.1 - 8.9e-25 86.9 0.1 2.2e-24 85.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 GAM25711.1 - 1.6e-18 66.6 0.0 3.9e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 GAM25711.1 - 1.4e-14 54.2 0.0 3.2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 GAM25711.1 - 1.6e-11 43.5 0.0 0.00022 20.0 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 GAM25711.1 - 4e-10 39.2 0.0 8.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 GAM25711.1 - 1.5e-06 27.7 0.0 3.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 GAM25711.1 - 3.2e-06 27.0 0.0 9.8e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 GAM25711.1 - 4.4e-06 26.1 0.0 1.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Sec1 PF00995.18 GAM25712.1 - 8.6e-147 490.1 7.9 9.9e-147 489.9 5.5 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase_Tyr PF07714.12 GAM25713.1 - 2e-69 233.5 0.0 3.5e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM25713.1 - 4.4e-67 225.9 0.1 1.2e-66 224.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 GAM25713.1 - 0.002 17.1 0.0 0.0042 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Limkain-b1 PF11608.3 GAM25713.1 - 0.0038 16.9 1.6 0.0038 16.9 1.1 1.9 2 0 0 2 2 2 1 Limkain b1 Kdo PF06293.9 GAM25713.1 - 0.036 13.1 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0047 PF01894.12 GAM25713.1 - 0.038 13.8 0.3 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 DUF2638 PF10937.3 GAM25714.1 - 0.006 17.5 2.4 0.085 13.8 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2638) Phage_Mu_Gam PF07352.7 GAM25714.1 - 0.7 9.4 5.9 0.1 12.1 0.9 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein EcoR124_C PF12008.3 GAM25714.1 - 4.3 6.4 11.4 0.13 11.4 0.9 2.6 3 0 0 3 3 3 0 Type I restriction and modification enzyme - subunit R C terminal bZIP_C PF12498.3 GAM25714.1 - 8.3 7.6 10.5 0.61 11.3 2.9 2.1 2 0 0 2 2 2 0 Basic leucine-zipper C terminal CDC27 PF09507.5 GAM25715.1 - 7.9e-10 38.5 46.4 7.9e-10 38.5 32.1 3.1 1 1 1 2 2 2 1 DNA polymerase subunit Cdc27 Sugar_tr PF00083.19 GAM25716.1 - 6.5e-108 361.1 35.1 7.5e-108 360.9 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 GAM25716.1 - 8.7e-49 166.1 40.3 2.6e-33 115.1 5.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM25716.1 - 8e-15 54.1 19.2 1.9e-09 36.4 1.7 3.3 1 1 1 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 GAM25716.1 - 1.7e-12 46.3 12.8 1.1e-09 37.0 3.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 GAM25716.1 - 1.7e-06 27.7 5.8 0.0025 17.5 1.0 2.9 2 0 0 2 2 2 2 MFS_1 like family DUF1228 PF06779.9 GAM25716.1 - 0.0009 19.2 0.8 0.0089 16.0 0.1 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1228) Clat_adaptor_s PF01217.15 GAM25717.1 - 9.1e-37 125.9 4.6 1.1e-36 125.7 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNAP PF14938.1 GAM25718.1 - 8.2e-12 44.8 10.8 3.9e-11 42.6 3.4 2.5 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 GAM25718.1 - 7.3e-09 35.4 3.2 1.3e-06 28.2 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM25718.1 - 3.3e-08 33.0 7.4 1.9e-06 27.4 0.2 3.5 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 GAM25718.1 - 1.3e-05 24.6 0.6 0.0018 17.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM25718.1 - 1.6e-05 24.4 8.9 0.00033 20.3 0.1 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM25718.1 - 5.1e-05 22.6 8.2 0.00089 18.7 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM25718.1 - 0.00016 21.1 7.8 0.0027 17.3 0.4 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM25718.1 - 0.031 14.5 1.2 2.7 8.4 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM25718.1 - 0.039 14.0 9.9 0.44 10.7 0.1 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 GAM25718.1 - 0.1 12.5 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM25718.1 - 0.13 12.9 0.0 3.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CBP PF12192.3 GAM25718.1 - 0.21 11.5 2.0 14 5.7 0.0 3.3 2 1 0 3 3 3 0 Fungal calcium binding protein TPR_6 PF13174.1 GAM25718.1 - 0.89 10.1 3.2 13 6.5 0.0 4.1 6 0 0 6 6 4 0 Tetratricopeptide repeat UCH PF00443.24 GAM25719.1 - 6.6e-48 163.1 2.9 6.6e-48 163.1 2.0 2.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM25719.1 - 9.2e-24 84.3 0.9 9.2e-24 84.3 0.6 3.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF4407 PF14362.1 GAM25719.1 - 8.1 5.2 11.1 14 4.5 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TP1 PF02079.11 GAM25720.1 - 0.033 13.9 2.6 0.08 12.7 1.8 1.6 1 0 0 1 1 1 0 Nuclear transition protein 1 CENP-B_dimeris PF09026.5 GAM25720.1 - 0.2 11.9 9.6 0.79 10.0 0.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MIP-T3 PF10243.4 GAM25720.1 - 0.57 8.5 23.6 0.91 7.9 16.3 1.3 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 GAM25720.1 - 2.3 7.9 20.6 1.7 8.4 5.8 2.1 2 0 0 2 2 2 0 DDHD domain Mucin PF01456.12 GAM25720.1 - 3.1 7.5 22.7 0.6 9.8 13.0 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein MGC-24 PF05283.6 GAM25720.1 - 3.2 7.5 15.2 5.2 6.8 10.5 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Pkinase PF00069.20 GAM25721.1 - 1e-72 244.4 0.0 1.2e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25721.1 - 1.6e-38 132.2 0.0 1.9e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM25721.1 - 4.2e-06 25.9 0.0 0.00025 20.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 GAM25721.1 - 1.3e-05 24.3 0.1 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM25721.1 - 0.021 14.1 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RinB PF06116.7 GAM25721.1 - 0.06 12.9 1.7 0.2 11.2 0.8 2.1 2 0 0 2 2 2 0 Transcriptional activator RinB APH PF01636.18 GAM25721.1 - 0.12 12.1 0.1 1.5 8.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4328 PF14219.1 GAM25722.1 - 0.098 11.9 1.5 0.1 11.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) SpoIIIAC PF06686.6 GAM25722.1 - 0.19 11.5 2.9 0.3 10.9 2.0 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Tetraspannin PF00335.15 GAM25722.1 - 0.28 10.4 1.8 0.28 10.4 1.3 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF1673 PF07895.6 GAM25722.1 - 0.31 10.5 1.3 0.31 10.5 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) CcoS PF03597.10 GAM25722.1 - 1.1 8.7 5.3 0.25 10.8 1.0 1.8 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type RseC_MucC PF04246.7 GAM25722.1 - 1.4 8.5 3.3 1.4 8.4 2.3 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FAM196 PF15265.1 GAM25723.1 - 1.2 8.2 15.4 1.5 8.0 10.6 1.0 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.8 GAM25723.1 - 1.4 8.7 11.3 1.9 8.3 7.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 GAM25723.1 - 2.3 6.3 18.0 2.9 6.0 12.5 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 GAM25723.1 - 5 6.2 8.5 6.5 5.8 5.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF936 PF06075.7 GAM25723.1 - 9.6 4.9 16.0 11 4.8 11.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Laminin_G_3 PF13385.1 GAM25725.1 - 5.7e-12 46.1 0.9 5.7e-12 46.1 0.6 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily HEAT_2 PF13646.1 GAM25725.1 - 0.21 11.8 2.3 49 4.3 0.0 4.6 5 0 0 5 5 5 0 HEAT repeats FNIP PF05725.7 GAM25726.1 - 3.2e-97 318.2 37.1 3.8e-14 52.3 0.1 13.0 9 5 4 13 13 13 13 FNIP Repeat Mito_carr PF00153.22 GAM25727.1 - 3.2e-70 231.9 2.7 4.6e-25 87.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_63 PF03200.11 GAM25728.1 - 1.3e-06 26.6 10.2 6.3e-06 24.3 0.7 4.0 3 2 0 3 3 3 3 Mannosyl oligosaccharide glucosidase OHCU_decarbox PF09349.5 GAM25729.1 - 4.5e-37 127.8 0.1 7.2e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 OHCU decarboxylase Amidohydro_1 PF01979.15 GAM25729.1 - 3.3e-27 96.0 0.0 5.2e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 GAM25729.1 - 3.2e-22 79.8 0.0 4.4e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 GAM25729.1 - 4.6e-09 35.9 0.3 1.7e-08 34.1 0.2 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM25729.1 - 9.5e-06 25.0 0.8 0.00022 20.5 0.0 2.8 2 1 1 3 3 3 1 Amidohydrolase family Sec23_trunk PF04811.10 GAM25729.1 - 0.052 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Redoxin PF08534.5 GAM25730.1 - 2.7e-10 39.9 0.0 4.4e-10 39.2 0.0 1.3 1 1 0 1 1 1 1 Redoxin HAD PF12710.2 GAM25731.1 - 9.2e-13 48.7 0.0 1.6e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM25731.1 - 4.3e-07 30.5 0.0 5.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM25731.1 - 9e-06 25.4 0.2 6.4e-05 22.6 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 GAM25731.1 - 1.3e-05 24.5 0.0 3.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.1 GAM25731.1 - 0.004 17.3 0.0 0.0094 16.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF4358 PF14270.1 GAM25731.1 - 0.056 13.3 1.5 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DUF1212 PF06738.7 GAM25731.1 - 0.14 11.6 0.2 0.24 10.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Coiled PF05710.7 GAM25733.1 - 4 7.9 13.2 5.9 7.4 9.2 1.4 1 1 0 1 1 1 0 Coiled coil EGF_2 PF07974.8 GAM25734.1 - 1e-07 32.0 38.5 0.00018 21.5 8.8 3.3 3 0 0 3 3 3 2 EGF-like domain FNIP PF05725.7 GAM25735.1 - 6.7e-78 256.4 15.7 1.9e-13 50.1 0.0 8.6 6 1 4 10 10 10 9 FNIP Repeat EGF_2 PF07974.8 GAM25736.1 - 1.8e-05 24.7 35.6 0.0016 18.5 10.2 2.8 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 GAM25736.1 - 1.7 8.8 13.5 0.94 9.6 2.4 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.8 GAM25737.1 - 1.3e-08 34.8 32.4 0.00038 20.5 10.4 3.2 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 GAM25737.1 - 1.5 9.0 13.1 2.2 8.5 1.2 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.8 GAM25738.1 - 3.2e-08 33.5 33.9 0.00081 19.5 7.6 3.0 2 0 0 2 2 2 2 EGF-like domain Nodulin-like PF06813.8 GAM25739.1 - 9.9e-23 80.6 8.7 9.9e-23 80.6 6.1 2.3 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.11 GAM25739.1 - 1.1e-14 53.9 29.8 1.3e-07 30.7 6.2 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily HCaRG PF07258.9 GAM25740.1 - 1.2e-30 106.3 0.5 1.4e-30 106.1 0.4 1.0 1 0 0 1 1 1 1 HCaRG protein DUF4435 PF14491.1 GAM25740.1 - 0.097 12.4 1.8 0.15 11.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) K-box PF01486.12 GAM25740.1 - 0.27 11.0 1.9 0.49 10.2 0.2 2.3 3 0 0 3 3 3 0 K-box region Sulfotransfer_2 PF03567.9 GAM25741.1 - 8.1e-09 35.5 1.8 1.4e-08 34.7 0.2 2.1 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 GAM25741.1 - 4.7e-05 22.2 0.1 0.00047 18.9 0.1 2.2 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 GAM25741.1 - 0.032 13.4 0.4 0.11 11.7 0.3 2.1 1 1 0 1 1 1 0 Sulfotransferase domain G-alpha PF00503.15 GAM25742.1 - 2.6e-106 355.6 12.6 3.3e-106 355.2 8.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit PH PF00169.24 GAM25742.1 - 6.3e-19 68.1 0.4 6.3e-19 68.1 0.2 2.2 2 0 0 2 2 2 1 PH domain Arf PF00025.16 GAM25742.1 - 4.1e-13 48.9 0.7 3.7e-10 39.3 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM25742.1 - 4.5e-05 22.6 8.5 7.4e-05 21.9 0.9 2.8 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region PH_11 PF15413.1 GAM25742.1 - 0.00037 20.7 4.1 0.002 18.3 2.1 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM25742.1 - 0.002 18.1 0.1 0.0073 16.3 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Miro PF08477.8 GAM25742.1 - 0.017 15.6 2.8 6.5 7.2 0.0 3.6 4 0 0 4 4 4 0 Miro-like protein GTP_EFTU PF00009.22 GAM25742.1 - 0.031 13.7 0.8 0.84 9.0 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PH_9 PF15410.1 GAM25742.1 - 0.039 14.1 0.1 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Rsa3 PF14615.1 GAM25743.1 - 5.1e-09 35.2 0.2 9.9e-09 34.3 0.2 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 zf-RING_2 PF13639.1 GAM25744.1 - 3.6e-11 42.7 7.3 3.6e-11 42.7 5.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM25744.1 - 2.2e-09 37.1 8.4 2.2e-09 37.1 5.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM25744.1 - 4.4e-08 32.6 7.8 4.4e-08 32.6 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM25744.1 - 3.8e-07 29.7 6.2 3.8e-07 29.7 4.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 GAM25744.1 - 7.3e-07 28.7 7.4 7.3e-07 28.7 5.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM25744.1 - 5.7e-05 22.9 8.8 0.00018 21.2 6.1 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Helicase_C PF00271.26 GAM25744.1 - 0.0004 20.1 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.2 GAM25744.1 - 0.00066 19.7 1.8 0.00066 19.7 1.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger Dicty_REP PF05086.7 GAM25744.1 - 0.0015 16.4 3.9 0.0015 16.4 2.7 1.6 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein zf-RING_UBOX PF13445.1 GAM25744.1 - 0.0032 17.1 7.8 0.0037 16.9 3.1 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAM25744.1 - 0.031 14.0 4.0 0.078 12.7 2.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 GAM25744.1 - 0.053 13.0 4.2 0.14 11.7 2.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Mucin PF01456.12 GAM25744.1 - 0.32 10.7 23.3 0.63 9.8 16.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 GAM25744.1 - 0.54 10.0 18.0 1.2 8.9 12.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Prok-RING_4 PF14447.1 GAM25744.1 - 0.94 9.0 4.8 6.5 6.3 3.3 2.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 GAM25744.1 - 1.2 8.9 7.2 0.05 13.4 0.9 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SSP160 PF06933.6 GAM25744.1 - 4.6 5.1 19.9 7.1 4.4 13.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DZR PF12773.2 GAM25744.1 - 7.7 6.4 11.8 18 5.2 3.0 3.2 2 1 0 2 2 2 0 Double zinc ribbon SNF2_N PF00176.18 GAM25745.1 - 4.2e-68 229.3 0.7 8.4e-68 228.3 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain UPF0167 PF03691.9 GAM25745.1 - 0.0031 16.9 2.1 0.0058 16.0 0.7 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0167) PHD PF00628.24 GAM25745.1 - 0.0033 17.0 9.7 0.0033 17.0 6.7 2.4 2 0 0 2 2 2 1 PHD-finger zf-CW PF07496.10 GAM25745.1 - 0.038 13.6 3.3 0.12 12.0 2.3 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger DUF1640 PF07798.6 GAM25746.1 - 0.016 15.2 1.9 0.039 13.9 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2547 PF10818.3 GAM25746.1 - 1.6 9.3 18.7 0.53 10.9 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2547) T4_deiodinase PF00837.12 GAM25747.1 - 2.8e-25 88.6 0.0 3.3e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Iodothyronine deiodinase Sulfate_transp PF00916.15 GAM25749.1 - 3.8e-70 236.0 14.1 1.2e-69 234.4 8.8 2.5 3 0 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM25749.1 - 4.7e-28 96.6 3.8 4.7e-28 96.6 2.6 3.3 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM25749.1 - 8.7e-23 79.9 0.0 2.1e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 GAM25749.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain Mitofilin PF09731.4 GAM25751.1 - 0.0011 17.7 25.1 0.0011 17.7 17.4 2.9 3 0 0 3 3 3 2 Mitochondrial inner membrane protein DUF3086 PF11285.3 GAM25751.1 - 0.0085 14.9 0.0 0.0085 14.9 0.0 2.9 4 1 0 4 4 4 1 Protein of unknown function (DUF3086) CDC27 PF09507.5 GAM25751.1 - 0.44 9.7 72.4 0.047 12.9 35.2 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 NmrA PF05368.8 GAM25752.1 - 1.7e-10 40.5 0.0 5.3e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 GAM25752.1 - 0.00029 20.8 0.0 0.00063 19.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Kelch_4 PF13418.1 GAM25753.1 - 7.5e-13 48.0 2.2 3.4e-07 29.9 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25753.1 - 4e-11 42.7 0.4 8.8e-05 22.5 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM25753.1 - 1.8e-10 40.4 3.9 0.0008 19.4 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 GAM25753.1 - 2e-08 33.6 1.9 0.00086 18.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM25753.1 - 0.0009 19.1 3.8 0.23 11.4 0.2 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.10 GAM25753.1 - 0.0017 18.0 4.2 1.2 9.0 1.3 3.1 2 1 1 3 3 3 2 Kelch motif Baculo_PEP_C PF04513.7 GAM25753.1 - 0.0019 18.0 2.1 0.0079 16.0 1.1 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Rax2 PF12768.2 GAM25753.1 - 0.0061 15.8 2.7 0.0099 15.1 0.1 2.3 2 1 0 2 2 2 1 Cortical protein marker for cell polarity SF-assemblin PF06705.6 GAM25753.1 - 0.0067 15.6 3.6 0.0067 15.6 2.5 1.6 2 0 0 2 2 2 1 SF-assemblin/beta giardin Reo_sigmaC PF04582.7 GAM25753.1 - 0.0099 15.0 2.5 0.0099 15.0 1.7 2.1 1 1 0 2 2 2 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 GAM25753.1 - 0.021 14.6 3.2 0.051 13.3 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 GAM25753.1 - 0.03 11.6 3.8 0.041 11.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LON PF02190.11 GAM25753.1 - 0.037 13.7 0.7 0.065 12.9 0.5 1.3 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain PLU-1 PF08429.6 GAM25753.1 - 0.042 12.7 0.5 0.088 11.6 0.3 1.4 1 0 0 1 1 1 0 PLU-1-like protein Scaffolding_pro PF11418.3 GAM25753.1 - 0.14 12.5 1.4 3.7 7.9 0.1 3.0 1 1 1 3 3 3 0 Phi29 scaffolding protein DUF948 PF06103.6 GAM25753.1 - 0.22 11.3 4.7 0.22 11.4 1.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 GAM25754.1 - 4.6e-35 121.0 0.2 1.1e-31 109.8 0.0 2.8 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25754.1 - 1.7e-32 112.5 0.1 7.8e-30 103.7 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase DUF605 PF04652.11 GAM25754.1 - 0.037 13.4 11.5 0.046 13.1 8.0 1.1 1 0 0 1 1 1 0 Vta1 like Kinase-like PF14531.1 GAM25754.1 - 0.045 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Dynamin_N PF00350.18 GAM25755.1 - 2.3e-09 37.2 0.0 3.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family DUF258 PF03193.11 GAM25755.1 - 4.8e-05 22.5 0.0 8.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM25755.1 - 9.6e-05 22.6 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 GAM25755.1 - 0.00023 21.0 0.0 0.00075 19.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.7 GAM25755.1 - 0.00061 19.1 0.1 0.00061 19.1 0.1 2.0 2 1 1 3 3 3 1 Poxvirus A32 protein AAA_33 PF13671.1 GAM25755.1 - 0.00082 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 GAM25755.1 - 0.0013 18.4 0.1 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 GAM25755.1 - 0.0016 17.5 0.1 0.0016 17.5 0.1 1.5 2 0 0 2 2 2 1 Septin AAA_29 PF13555.1 GAM25755.1 - 0.0029 17.1 0.8 0.0078 15.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM25755.1 - 0.01 16.6 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 GAM25755.1 - 0.011 15.2 0.2 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 GAM25755.1 - 0.015 14.7 0.3 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 GAM25755.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 GAM25755.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM25755.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 GAM25755.1 - 0.021 14.8 0.3 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 GAM25755.1 - 0.025 13.5 0.1 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.1 GAM25755.1 - 0.027 14.0 0.1 0.055 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 GAM25755.1 - 0.046 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 GAM25755.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 GAM25755.1 - 0.06 13.8 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 GAM25755.1 - 0.082 12.4 0.6 0.9 9.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 GAM25755.1 - 0.098 12.1 0.1 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 GAM25755.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase HECT PF00632.20 GAM25756.1 - 4.2e-99 331.6 1.9 9.8e-99 330.4 0.1 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 GAM25756.1 - 4.7e-28 98.4 9.3 4.7e-28 98.4 6.5 3.4 2 2 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 GAM25756.1 - 5.2e-27 94.5 3.4 5.2e-27 94.5 2.4 5.6 6 1 1 7 7 7 2 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 GAM25756.1 - 9.1e-24 83.4 3.1 9.1e-24 83.4 2.1 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 GAM25756.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain DUF2254 PF10011.4 GAM25757.1 - 0.65 8.4 7.0 0.032 12.7 0.8 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Glyco_tranf_2_3 PF13641.1 GAM25758.1 - 4.3e-05 23.4 0.1 7.1e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ank_2 PF12796.2 GAM25759.1 - 3.8e-49 164.9 23.9 4e-10 39.8 1.6 10.5 7 4 3 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25759.1 - 5e-33 112.8 22.7 1.8e-06 28.3 0.3 12.0 8 2 3 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.25 GAM25759.1 - 4.1e-27 92.6 37.1 8.2e-06 25.3 0.4 13.6 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.1 GAM25759.1 - 2.2e-23 81.7 24.0 8.6e-05 22.6 0.4 12.7 8 3 5 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM25759.1 - 2.6e-18 64.2 28.5 0.096 12.9 0.0 15.6 16 0 0 16 16 16 4 Ankyrin repeat SecA_DEAD PF07517.9 GAM25759.1 - 1.6e-06 27.6 0.0 0.0016 17.7 0.0 2.4 1 1 1 2 2 2 2 SecA DEAD-like domain SecA_PP_bind PF01043.15 GAM25759.1 - 0.013 15.8 0.0 0.076 13.3 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Helicase_C PF00271.26 GAM25759.1 - 0.029 14.2 0.0 0.093 12.6 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ank_2 PF12796.2 GAM25760.1 - 7.1e-06 26.2 0.0 1.9e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM25760.1 - 0.0011 19.0 0.2 0.4 11.0 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 GAM25760.1 - 0.02 14.7 0.1 0.33 10.8 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.1 GAM25760.1 - 0.16 12.5 0.5 55 4.4 0.0 3.3 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Bromodomain PF00439.20 GAM25762.1 - 1.8e-17 63.0 1.1 3.8e-17 61.9 0.8 1.6 1 0 0 1 1 1 1 Bromodomain Sec23_trunk PF04811.10 GAM25763.1 - 1.4e-64 217.7 0.0 2.4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM25763.1 - 2.5e-30 103.9 0.9 5e-30 102.9 0.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 GAM25763.1 - 8.9e-30 103.0 0.2 1.7e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 GAM25763.1 - 7.7e-13 47.7 7.3 1.4e-12 46.9 5.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 GAM25763.1 - 6.9e-12 44.8 0.0 1.8e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Gelsolin repeat Ribosomal_S5_C PF03719.10 GAM25764.1 - 0.027 13.7 0.1 0.77 9.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Dicty_REP PF05086.7 GAM25764.1 - 0.17 9.6 10.1 0.27 8.9 7.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ATP11 PF06644.6 GAM25764.1 - 0.17 11.3 5.0 0.32 10.4 3.5 1.4 1 0 0 1 1 1 0 ATP11 protein Mucin PF01456.12 GAM25764.1 - 8.9 6.0 14.4 2.1 8.1 7.2 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein FNIP PF05725.7 GAM25765.1 - 3.8e-27 93.9 25.7 4.3e-09 36.1 1.1 6.4 3 2 5 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM25765.1 - 0.0011 18.9 0.9 1.3 8.9 0.1 4.1 1 1 3 4 4 4 2 Protein of unknown function (DUF1769) TIG PF01833.19 GAM25769.1 - 7.3e-55 182.9 154.9 1.8e-14 53.4 0.4 18.4 18 1 0 18 18 18 10 IPT/TIG domain CarboxypepD_reg PF13620.1 GAM25769.1 - 1.7e-06 28.0 3.9 0.00018 21.4 0.4 6.2 5 1 0 5 5 5 2 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 GAM25769.1 - 0.0019 18.2 8.0 0.0033 17.4 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4198) DUF2012 PF09430.5 GAM25769.1 - 0.0036 17.1 1.2 0.35 10.6 0.1 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2012) TIG PF01833.19 GAM25770.1 - 4.4e-26 90.6 112.6 1.6e-11 44.0 1.7 14.2 12 2 1 13 13 13 8 IPT/TIG domain DNase_II PF03265.10 GAM25770.1 - 5.4e-19 68.3 0.1 6.6e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II PRKCSH_1 PF13015.1 GAM25770.1 - 6.5e-11 41.9 3.3 0.14 11.6 0.1 4.7 3 1 0 4 4 4 4 Glucosidase II beta subunit-like protein CarboxypepD_reg PF13620.1 GAM25770.1 - 1.8e-05 24.7 1.7 1.8e-05 24.7 1.2 4.9 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.1 GAM25770.1 - 0.00037 20.5 0.1 0.01 15.9 0.0 3.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II Cna_B PF05738.8 GAM25770.1 - 0.00097 18.8 0.5 0.00097 18.8 0.4 2.9 2 0 0 2 2 2 1 Cna protein B-type domain P3A PF08727.6 GAM25770.1 - 0.062 12.6 0.2 2.9 7.2 0.0 3.0 3 0 0 3 3 3 0 Poliovirus 3A protein like Qn_am_d_aIII PF09099.5 GAM25770.1 - 0.67 10.3 4.2 12 6.2 0.0 3.8 4 0 0 4 4 4 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Coiled PF05710.7 GAM25771.1 - 5 7.6 13.4 7.7 7.0 9.3 1.4 1 1 0 1 1 1 0 Coiled coil ELO PF01151.13 GAM25772.1 - 3e-60 203.5 31.6 3.6e-60 203.3 21.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SBDS_C PF09377.5 GAM25773.1 - 4.2e-41 139.5 1.1 4.2e-41 139.5 0.8 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 GAM25773.1 - 1.6e-32 111.1 1.9 2.8e-32 110.3 1.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF3409 PF11889.3 GAM25773.1 - 0.079 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) DUF3596 PF12167.3 GAM25773.1 - 0.15 11.5 0.3 0.43 10.1 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3596) EB PF01683.13 GAM25774.1 - 1.6e-09 37.6 32.7 1.7e-05 24.7 3.9 4.2 2 2 2 4 4 4 4 EB module PTEN_C2 PF10409.4 GAM25775.1 - 1.8e-10 40.6 3.8 3.6e-10 39.6 2.6 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 GAM25775.1 - 3e-08 33.3 0.1 1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 GAM25775.1 - 5.1e-05 22.7 0.1 9.9e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 GAM25775.1 - 0.00022 20.6 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM25775.1 - 0.0026 18.0 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM25775.1 - 0.0046 17.0 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate WD40 PF00400.27 GAM25776.1 - 1.5e-33 113.4 13.7 1.7e-09 37.1 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM25776.1 - 0.009 15.7 0.0 5.5 6.8 0.0 3.5 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Miro PF08477.8 GAM25777.1 - 1.6e-07 31.8 0.6 0.0026 18.2 0.0 2.4 1 1 1 2 2 2 2 Miro-like protein Ras PF00071.17 GAM25777.1 - 4.2e-07 29.4 0.7 6.2e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 Ras family Arf PF00025.16 GAM25777.1 - 0.00017 20.8 0.3 0.0086 15.3 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM25777.1 - 0.00072 19.4 0.1 0.0025 17.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TMEM51 PF15345.1 GAM25777.1 - 0.0022 17.7 0.6 0.0033 17.1 0.4 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 SRPRB PF09439.5 GAM25777.1 - 0.0046 16.2 0.1 0.022 14.0 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Peptidase_S49_N PF08496.5 GAM25777.1 - 0.21 11.3 2.0 1.7 8.4 1.5 2.3 1 1 1 2 2 2 0 Peptidase family S49 N-terminal PBP1_TM PF14812.1 GAM25778.1 - 1.2 9.4 15.3 0.47 10.7 2.8 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4419 PF14388.1 GAM25779.1 - 1.4e-99 333.1 0.0 1.8e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) AAA_18 PF13238.1 GAM25780.1 - 2.8e-11 43.8 0.1 6.2e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM25780.1 - 4.5e-08 33.9 0.1 6.7e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM25780.1 - 1.1e-07 31.8 0.0 1.2e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 GAM25780.1 - 0.0018 17.6 0.0 0.0051 16.2 0.0 1.9 1 1 1 2 2 2 1 Dephospho-CoA kinase HA2 PF04408.18 GAM25782.1 - 4.1e-25 87.7 0.0 4.1e-25 87.7 0.0 2.9 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAM25782.1 - 1.2e-23 83.0 0.0 1.2e-23 83.0 0.0 2.6 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAM25782.1 - 5.4e-17 61.4 0.1 3e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM25782.1 - 2.5e-07 30.3 0.3 2.5e-07 30.3 0.2 2.7 2 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM25782.1 - 1.5e-05 25.1 3.0 2.4e-05 24.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain Flavi_DEAD PF07652.9 GAM25782.1 - 0.02 14.6 0.3 0.045 13.5 0.0 1.7 2 0 0 2 2 2 0 Flavivirus DEAD domain NST1 PF13945.1 GAM25782.1 - 0.14 12.2 20.2 0.25 11.4 14.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Pex14_N PF04695.8 GAM25782.1 - 8.6 6.4 20.2 18 5.4 14.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 GAM25782.1 - 8.6 4.4 43.5 12 3.9 30.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SPT16 PF08644.6 GAM25783.1 - 0.3 10.9 4.5 7.2 6.4 2.1 2.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) APG6 PF04111.7 GAM25784.1 - 1.4e-60 205.0 9.1 1.4e-60 205.0 6.3 2.7 2 1 0 2 2 2 1 Autophagy protein Apg6 Fes1 PF08609.5 GAM25785.1 - 4.6e-07 30.2 0.8 1.7e-06 28.4 0.2 2.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.18 GAM25785.1 - 0.0004 20.1 0.6 0.18 11.7 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM25785.1 - 0.0016 18.7 0.1 0.054 13.7 0.0 2.5 1 1 1 2 2 2 2 HEAT repeats HSP70 PF00012.15 GAM25786.1 - 7.3e-137 456.8 4.0 1.5e-136 455.7 2.8 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM25786.1 - 5.9e-13 48.1 0.1 1.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.11 GAM25786.1 - 0.033 13.8 0.0 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PSI_PsaH PF03244.9 GAM25788.1 - 0.11 11.7 0.1 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI Acetyltransf_7 PF13508.1 GAM25790.1 - 3.6e-10 39.8 0.0 7.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM25790.1 - 2.1e-08 34.0 0.0 9.9e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 GAM25790.1 - 1.9e-07 30.9 0.1 6.7e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM25790.1 - 0.00059 19.9 0.0 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM25790.1 - 0.0015 18.4 0.1 0.038 13.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM25790.1 - 0.026 14.4 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AFG1_ATPase PF03969.11 GAM25791.1 - 1.3e-105 353.2 0.3 1.2e-101 340.1 0.0 2.1 1 1 1 2 2 2 2 AFG1-like ATPase AAA_14 PF13173.1 GAM25791.1 - 0.00028 20.7 0.0 0.0025 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain Bac_DnaA PF00308.13 GAM25791.1 - 0.0013 18.3 2.8 0.46 10.0 0.1 2.9 3 1 0 3 3 3 2 Bacterial dnaA protein AAA_16 PF13191.1 GAM25791.1 - 0.0079 16.2 0.1 0.096 12.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM25791.1 - 0.018 15.1 0.0 0.27 11.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 GAM25791.1 - 0.022 14.9 0.5 0.29 11.3 0.0 3.0 3 1 0 3 3 3 0 RNA helicase AAA PF00004.24 GAM25791.1 - 0.082 13.1 0.0 2 8.6 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATXN-1_C PF12547.3 GAM25791.1 - 0.11 12.5 1.3 0.31 11.0 0.9 1.7 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Cupin_8 PF13621.1 GAM25792.1 - 5.3e-75 252.1 0.8 6.6e-75 251.8 0.6 1.1 1 0 0 1 1 1 1 Cupin-like domain dNK PF01712.14 GAM25792.1 - 0.022 14.6 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2040 PF09745.4 GAM25793.1 - 3.9e-32 110.7 22.1 3.9e-32 110.7 15.3 3.5 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Tim17 PF02466.14 GAM25794.1 - 5e-10 39.5 8.2 6.9e-10 39.0 5.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.1 GAM25794.1 - 0.012 15.1 5.1 0.012 15.1 3.6 2.7 2 1 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 GAM25794.1 - 0.064 12.9 13.8 0.099 12.3 2.0 3.0 2 1 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 GAM25794.1 - 0.2 11.3 18.2 0.16 11.6 4.9 2.7 3 0 0 3 3 3 0 Glycine zipper Bacteriocin_IIc PF10439.4 GAM25794.1 - 1.2 9.2 17.2 0.53 10.4 2.2 2.9 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.7 GAM25794.1 - 2.3 8.2 9.0 0.74 9.8 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Romo1 PF10247.4 GAM25794.1 - 4.8 7.4 13.7 50 4.2 1.2 3.5 2 2 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Dicty_REP PF05086.7 GAM25795.1 - 0.014 13.2 2.0 0.017 12.9 1.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RLL PF10036.4 GAM25795.1 - 0.083 12.3 0.6 0.12 11.8 0.4 1.1 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein DUF4407 PF14362.1 GAM25795.1 - 1.1 8.1 3.5 0.97 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YWFCY PF14293.1 GAM25795.1 - 1.3 8.8 5.1 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 YWFCY protein SSP160 PF06933.6 GAM25795.1 - 3.7 5.3 13.1 5.5 4.8 9.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Peptidase_S9 PF00326.16 GAM25796.1 - 6.3e-37 126.8 0.0 2.2e-36 125.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM25796.1 - 2.7e-10 40.1 0.0 4.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 GAM25796.1 - 5.8e-08 31.5 0.5 0.0036 15.8 0.1 3.6 3 1 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 GAM25796.1 - 7e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM25796.1 - 1.1e-06 28.6 0.0 2.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 GAM25796.1 - 4.2e-05 23.3 0.0 0.00017 21.3 0.0 1.9 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 GAM25796.1 - 8.7e-05 22.1 0.0 0.12 11.8 0.0 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAM25796.1 - 0.0018 17.7 0.0 0.03 13.7 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 GAM25796.1 - 0.012 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 GAM25796.1 - 0.026 13.8 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Glyoxalase_4 PF13669.1 GAM25797.1 - 1.3e-20 73.3 0.0 1.7e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 GAM25797.1 - 6.7e-11 42.2 0.0 7.7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM25797.1 - 5.3e-09 36.6 0.0 6.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 GAM25797.1 - 1.6e-06 28.1 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Citrate_synt PF00285.16 GAM25798.1 - 2.5e-106 355.3 0.0 3e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Thioredoxin PF00085.15 GAM25799.1 - 4.5e-68 225.5 5.3 2.1e-35 120.5 0.6 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 GAM25799.1 - 6.9e-25 87.5 0.7 1.6e-24 86.3 0.5 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 GAM25799.1 - 3.1e-16 59.5 3.2 4.2e-08 33.3 0.2 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM25799.1 - 1.8e-12 47.1 1.1 1.2e-05 25.3 0.1 3.6 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 GAM25799.1 - 6.8e-12 45.2 0.8 2e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 GAM25799.1 - 5.9e-11 42.5 1.7 2.6e-05 24.0 0.0 3.2 2 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 GAM25799.1 - 2.5e-09 36.8 0.9 0.00063 19.4 0.1 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 GAM25799.1 - 1.5e-05 24.5 4.0 0.013 15.0 0.3 2.6 2 1 0 2 2 2 2 Redoxin DDE_Tnp_1_2 PF13586.1 GAM25799.1 - 0.001 19.2 0.0 2.1 8.5 0.0 3.3 2 1 1 3 3 3 1 Transposase DDE domain Pox_G5 PF04599.7 GAM25799.1 - 0.0074 15.0 0.7 0.022 13.4 0.1 1.8 1 1 1 2 2 2 1 Poxvirus G5 protein DUF221 PF02714.10 GAM25799.1 - 0.033 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 DUF2117 PF09890.4 GAM25799.1 - 0.058 12.5 0.6 0.095 11.8 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Mu-like_Com PF10122.4 GAM25799.1 - 0.063 12.3 1.6 8.4 5.5 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com LOH1CR12 PF10158.4 GAM25799.1 - 0.078 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor protein Thioredoxin_4 PF13462.1 GAM25799.1 - 0.83 9.6 5.4 2.7 7.9 0.3 3.4 2 2 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.19 GAM25799.1 - 2.5 8.1 4.9 17 5.4 0.2 2.9 2 1 0 2 2 2 0 Glutaredoxin PA28_beta PF02252.13 GAM25800.1 - 4.4e-40 136.5 1.5 5.8e-40 136.2 1.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit DUF2661 PF10860.3 GAM25800.1 - 0.098 12.8 1.9 0.1 12.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2661) UBN2 PF14223.1 GAM25800.1 - 0.22 11.3 2.2 1.6 8.5 0.0 2.4 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type IF4E PF01652.13 GAM25801.1 - 8.2e-43 145.7 0.0 1.2e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PH PF00169.24 GAM25802.1 - 0.0012 19.0 0.1 0.0031 17.6 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 GAM25802.1 - 0.0018 18.3 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain UBA_4 PF14555.1 GAM25802.1 - 0.0037 16.7 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain PH_11 PF15413.1 GAM25802.1 - 0.0049 17.1 1.6 0.034 14.4 0.2 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain LysM PF01476.15 GAM25802.1 - 0.0054 16.5 0.1 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 LysM domain Opiods_neuropep PF01160.13 GAM25802.1 - 0.03 14.0 1.0 0.1 12.4 0.7 1.9 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DUF2400 PF09674.5 GAM25802.1 - 0.23 11.0 2.2 0.28 10.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) ArsA_ATPase PF02374.10 GAM25803.1 - 1.1e-100 336.6 0.2 1.3e-100 336.3 0.2 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 GAM25803.1 - 2.3e-14 53.2 0.1 6.9e-14 51.7 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM25803.1 - 3.3e-07 30.3 0.1 5.9e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 GAM25803.1 - 1.3e-05 24.5 0.0 2.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 GAM25803.1 - 0.00067 19.1 0.1 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 GAM25803.1 - 0.00099 18.5 0.0 0.0028 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain YhjQ PF06564.7 GAM25803.1 - 0.01 15.2 0.0 0.021 14.1 0.0 1.7 1 1 0 1 1 1 0 YhjQ protein NB-ARC PF00931.17 GAM25803.1 - 0.016 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MipZ PF09140.6 GAM25803.1 - 0.022 13.8 1.1 0.051 12.6 0.2 2.1 2 1 0 2 2 2 0 ATPase MipZ Elf1 PF05129.8 GAM25803.1 - 0.035 13.8 0.1 0.077 12.7 0.1 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zeta_toxin PF06414.7 GAM25803.1 - 0.038 13.0 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 GAM25803.1 - 0.04 13.6 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 GAM25803.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 GAM25803.1 - 0.083 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF2009 PF09418.5 GAM25804.1 - 1.5e-188 627.3 0.5 1.8e-188 627.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 GAM25804.1 - 7.4e-07 28.9 5.7 1.7e-06 27.7 3.9 1.6 1 0 0 1 1 1 1 B-box zinc finger Cript PF10235.4 GAM25804.1 - 0.0048 17.2 2.5 0.014 15.7 1.7 1.8 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF3536 PF12055.3 GAM25804.1 - 0.05 12.7 0.0 0.22 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3536) zf-DHHC PF01529.15 GAM25804.1 - 1.9 7.8 6.1 1.2 8.4 1.6 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Secretin_N_2 PF07655.8 GAM25804.1 - 2.4 8.5 24.6 3.3 8.1 8.6 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain Lectin_legB PF00139.14 GAM25805.1 - 1.6e-22 80.0 0.0 2.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Legume lectin domain Rad4 PF03835.10 GAM25805.1 - 2.6e-14 52.8 2.1 4.9e-14 51.9 1.4 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 GAM25805.1 - 9.1e-13 48.4 0.0 4.3e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Lectin_leg-like PF03388.8 GAM25805.1 - 2.7e-09 36.5 0.1 4.2e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family ubiquitin PF00240.18 GAM25805.1 - 6.4e-07 28.6 0.5 1.7e-06 27.3 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin family Laminin_G_3 PF13385.1 GAM25805.1 - 0.012 15.9 0.3 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Arf PF00025.16 GAM25807.1 - 1.8e-61 206.3 1.4 2.1e-61 206.1 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM25807.1 - 2.3e-12 46.6 0.0 2.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM25807.1 - 1.1e-10 41.0 0.2 1.4e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAM25807.1 - 2.5e-10 40.8 0.0 3.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 GAM25807.1 - 8e-07 28.0 1.7 4.3e-05 22.3 0.5 2.7 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM25807.1 - 1.6e-05 24.1 0.1 2e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM25807.1 - 1.7e-05 24.7 0.1 2.3e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM25807.1 - 2.8e-05 23.6 0.5 0.0056 16.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAM25807.1 - 0.00046 20.3 0.1 0.00073 19.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM25807.1 - 0.0033 17.3 0.1 0.005 16.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 GAM25807.1 - 0.11 12.8 0.2 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 GAM25807.1 - 0.13 11.7 0.1 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ParA PF10609.4 GAM25810.1 - 4e-31 106.7 0.0 7.1e-31 105.9 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 GAM25810.1 - 2.9e-21 75.7 0.0 4.3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 GAM25810.1 - 3.4e-10 40.0 0.0 6.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 GAM25810.1 - 6e-08 32.0 0.9 5.6e-07 28.9 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 GAM25810.1 - 7.1e-07 28.5 0.0 3.6e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 GAM25810.1 - 4.3e-05 22.8 0.0 0.0002 20.6 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArgK PF03308.11 GAM25810.1 - 0.00027 19.7 0.1 0.00043 19.1 0.1 1.2 1 0 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 GAM25810.1 - 0.00052 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase GFO_IDH_MocA PF01408.17 GAM25810.1 - 0.00061 20.2 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold AAA_26 PF13500.1 GAM25810.1 - 0.0012 18.4 0.1 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 GAM25810.1 - 0.0023 17.3 0.0 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 GAM25810.1 - 0.0059 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein DUF258 PF03193.11 GAM25810.1 - 0.008 15.3 0.3 0.017 14.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 GAM25810.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAM25810.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM25810.1 - 0.012 15.7 0.1 0.063 13.4 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 GAM25810.1 - 0.021 14.5 4.7 0.035 13.8 0.1 2.9 3 1 0 3 3 3 0 Part of AAA domain NB-ARC PF00931.17 GAM25810.1 - 0.03 13.2 0.2 0.042 12.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 GAM25810.1 - 0.035 14.9 0.0 0.052 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 GAM25810.1 - 0.039 13.3 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein VirC1 PF07015.6 GAM25810.1 - 0.048 12.7 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein AAA_18 PF13238.1 GAM25810.1 - 0.086 13.1 0.2 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 GAM25810.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 GAM25810.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 GAM25810.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2631 PF10939.3 GAM25810.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) HSP20 PF00011.16 GAM25811.1 - 1.2e-22 79.6 0.1 1.5e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FG-GAP PF01839.18 GAM25812.1 - 1.3e-05 24.6 2.4 0.00034 20.2 0.0 2.9 2 0 0 2 2 2 1 FG-GAP repeat PQQ_2 PF13360.1 GAM25812.1 - 8.8e-05 22.0 0.1 7.5 5.9 0.0 4.3 4 0 0 4 4 4 3 PQQ-like domain VCBS PF13517.1 GAM25812.1 - 0.00022 21.4 0.1 0.028 14.7 0.0 3.0 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_L13 PF00572.13 GAM25813.1 - 1.1e-25 90.1 0.1 3.1e-25 88.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 E1-E2_ATPase PF00122.15 GAM25814.1 - 5.9e-22 77.8 3.2 1.6e-21 76.3 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 GAM25814.1 - 3.1e-16 60.0 0.0 6.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM25814.1 - 2.7e-11 44.3 0.0 9.8e-10 39.2 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM25814.1 - 1.2e-08 34.8 0.0 3.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM25814.1 - 0.0063 16.1 0.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 GAM25815.1 - 2e-92 310.1 0.0 2.2e-92 309.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RCC1 PF00415.13 GAM25816.1 - 5.3e-69 228.2 23.5 5.6e-14 52.0 0.2 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 GAM25816.1 - 1.7e-57 195.0 0.2 3.5e-57 193.9 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 GAM25816.1 - 4.8e-39 134.0 0.4 2.6e-38 131.6 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain RCC1_2 PF13540.1 GAM25816.1 - 5.5e-31 105.4 39.5 2.1e-08 33.5 0.2 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.12 GAM25816.1 - 5.1e-24 84.7 0.0 2.1e-23 82.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM25816.1 - 0.0017 17.4 2.3 0.037 13.0 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM25816.1 - 0.0039 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family FNIP PF05725.7 GAM25817.1 - 2e-70 232.5 21.4 7.1e-15 54.6 0.5 8.1 8 0 0 8 8 8 7 FNIP Repeat RhoGEF PF00621.15 GAM25818.1 - 3e-79 265.0 15.4 5.3e-47 160.0 2.8 2.5 2 0 0 2 2 2 2 RhoGEF domain RhoGAP PF00620.22 GAM25818.1 - 6.8e-43 145.9 0.3 9.1e-42 142.2 0.0 2.7 2 0 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.1 GAM25818.1 - 1.6e-12 46.8 0.2 2.8e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM25818.1 - 2e-09 36.6 0.1 3.9e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM25818.1 - 1.1e-07 31.2 0.0 2.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 GAM25818.1 - 3.3e-05 24.0 0.4 0.00011 22.2 0.2 2.0 1 0 0 1 1 1 1 PH domain FHA PF00498.21 GAM25819.1 - 1.1e-05 25.4 0.0 2.8e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain DUF3774 PF12609.3 GAM25819.1 - 1.3 9.8 4.3 1.8 9.4 0.4 2.7 2 0 0 2 2 2 0 Wound-induced protein zf-HIT PF04438.11 GAM25821.1 - 7.3e-07 28.7 11.5 1.2e-06 28.0 8.0 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF2457 PF10446.4 GAM25821.1 - 0.013 14.2 10.1 0.019 13.7 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-MYND PF01753.13 GAM25821.1 - 0.58 10.0 12.0 1.2 9.0 8.3 1.6 1 0 0 1 1 1 0 MYND finger PBP1_TM PF14812.1 GAM25821.1 - 1.3 9.3 9.1 2.8 8.2 6.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 GAM25821.1 - 8 5.9 9.6 16 4.9 6.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Peptidase_C1 PF00112.18 GAM25822.1 - 2.5e-16 60.2 0.0 3.8e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C39_2 PF13529.1 GAM25822.1 - 0.00057 20.2 0.0 0.0024 18.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C1_2 PF03051.10 GAM25822.1 - 0.024 13.1 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family TerB PF05099.8 GAM25822.1 - 0.08 12.6 1.3 0.17 11.6 0.3 2.1 2 1 0 2 2 2 0 Tellurite resistance protein TerB DUF287 PF03384.9 GAM25822.1 - 0.083 13.0 0.1 8.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 Pro-kuma_activ PF09286.6 GAM25824.1 - 5.9e-36 123.6 0.1 1e-35 122.8 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM25824.1 - 0.00011 21.5 1.1 0.00023 20.4 0.7 1.6 1 0 0 1 1 1 1 Subtilase family Gpi16 PF04113.9 GAM25826.1 - 1.3e-82 277.6 0.0 3e-82 276.4 0.0 1.6 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LRR_4 PF12799.2 GAM25827.1 - 3.7e-29 99.8 35.1 3.6e-06 26.4 1.7 8.4 2 2 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM25827.1 - 2.5e-26 91.2 30.2 3e-08 33.2 2.4 5.7 5 0 0 5 5 5 4 Leucine rich repeat Pkinase_Tyr PF07714.12 GAM25827.1 - 1e-23 83.7 0.0 1.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM25827.1 - 6.8e-15 54.9 0.0 2e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.28 GAM25827.1 - 8e-13 46.5 28.9 0.057 13.4 0.0 12.6 13 0 0 13 13 12 2 Leucine Rich Repeat RGS PF00615.14 GAM25827.1 - 4.4e-12 46.1 1.6 1.6e-11 44.3 1.1 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain RhoGAP PF00620.22 GAM25827.1 - 1.7e-10 40.7 2.9 8.2e-10 38.4 0.5 2.8 2 0 0 2 2 2 1 RhoGAP domain Kelch_4 PF13418.1 GAM25827.1 - 7.2e-08 32.0 0.2 0.0027 17.4 0.1 3.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM25827.1 - 7.8e-06 25.8 0.0 0.0036 17.4 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 GAM25827.1 - 8.4e-05 22.4 0.1 0.0094 15.8 0.0 2.8 2 0 0 2 2 2 1 Kelch motif LRR_7 PF13504.1 GAM25827.1 - 0.00012 21.7 30.9 6.8 7.3 0.0 11.0 11 0 0 11 11 10 1 Leucine rich repeat Kelch_2 PF07646.10 GAM25827.1 - 0.00014 21.4 0.2 0.0015 18.2 0.1 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.20 GAM25827.1 - 0.001 18.5 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Miro PF08477.8 GAM25827.1 - 0.0094 16.4 0.0 0.032 14.7 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein DUF1759 PF03564.10 GAM25827.1 - 0.01 15.6 1.2 1.1 9.0 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) AAA_16 PF13191.1 GAM25827.1 - 0.039 13.9 0.1 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain LRR_6 PF13516.1 GAM25827.1 - 0.04 13.9 32.9 2.7 8.3 0.0 9.8 10 1 1 11 11 9 0 Leucine Rich repeat LRR_9 PF14580.1 GAM25827.1 - 0.32 10.5 8.5 1.7 8.1 1.7 3.0 1 1 1 2 2 2 0 Leucine-rich repeat Rer1 PF03248.8 GAM25828.1 - 3.6e-66 222.1 4.6 4e-66 221.9 3.2 1.0 1 0 0 1 1 1 1 Rer1 family 2TM PF13239.1 GAM25828.1 - 0.28 11.2 8.5 0.56 10.2 0.4 2.2 2 0 0 2 2 2 0 2TM domain DUF788 PF05620.6 GAM25828.1 - 1.4 8.7 5.3 7.2 6.4 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) WD40 PF00400.27 GAM25829.1 - 1.1e-47 158.2 12.6 2.8e-11 42.8 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM25829.1 - 6.3e-06 24.7 0.1 0.00052 18.4 0.0 2.8 2 1 1 3 3 3 2 Cytochrome D1 heme domain Glycophorin_A PF01102.13 GAM25830.1 - 0.011 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 Glycophorin A CbiM PF01891.11 GAM25830.1 - 0.2 11.2 2.9 0.33 10.5 2.0 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region SET PF00856.23 GAM25831.1 - 2.8e-14 53.7 0.0 1.1e-11 45.2 0.0 2.3 2 0 0 2 2 2 2 SET domain zf-HIT PF04438.11 GAM25831.1 - 0.0032 17.0 3.4 0.0032 17.0 2.4 2.7 3 0 0 3 3 3 1 HIT zinc finger Glyco_hydro_42 PF02449.10 GAM25831.1 - 0.014 14.5 0.1 0.039 13.0 0.0 1.7 1 1 0 1 1 1 0 Beta-galactosidase RNA_GG_bind PF10258.4 GAM25832.1 - 3.5e-10 39.4 0.4 4.9e-05 22.9 0.2 2.7 2 0 0 2 2 2 2 PHAX RNA-binding domain Serinc PF03348.10 GAM25832.1 - 0.52 8.9 2.6 1 8.0 1.8 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) zf-ZPR1 PF03367.8 GAM25832.1 - 1 8.5 9.7 0.062 12.4 2.4 2.1 2 2 0 2 2 2 0 ZPR1 zinc-finger domain AKNA PF12443.3 GAM25833.1 - 0.1 12.6 0.7 0.1 12.6 0.5 1.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Spore_II_R PF09551.5 GAM25833.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Spore_GerAC PF05504.6 GAM25833.1 - 0.27 11.0 2.7 0.32 10.7 1.9 1.1 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Selenoprotein_S PF06936.6 GAM25833.1 - 0.4 10.1 5.8 0.68 9.4 4.0 1.4 1 1 0 1 1 1 0 Selenoprotein S (SelS) DUF883 PF05957.8 GAM25833.1 - 1.3 9.4 5.2 1.7 9.0 3.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATP-synt_E PF05680.7 GAM25833.1 - 1.5 8.8 5.2 2.1 8.3 3.6 1.3 1 0 0 1 1 1 0 ATP synthase E chain DUF3584 PF12128.3 GAM25834.1 - 0.44 7.8 40.1 0.011 13.1 14.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4192 PF13830.1 GAM25834.1 - 3.1 7.3 17.5 0.21 11.1 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4192) Vps5 PF09325.5 GAM25834.1 - 5 6.2 34.5 0.14 11.4 2.4 4.3 2 1 1 3 3 3 0 Vps5 C terminal like DUF3437 PF11919.3 GAM25835.1 - 2.9e-25 87.7 0.3 1.3e-24 85.7 0.2 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 GAM25835.1 - 0.0015 18.4 0.0 3.4 7.9 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat DUF2435 PF10363.4 GAM25835.1 - 0.0056 16.5 0.3 4 7.4 0.0 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Cir_N PF10197.4 GAM25836.1 - 2e-12 46.9 4.2 2e-12 46.9 2.9 2.5 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Spore_coat_CotO PF14153.1 GAM25836.1 - 2.3 7.6 16.8 0.079 12.4 2.7 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Sad1_UNC PF07738.8 GAM25837.1 - 2.9e-20 72.4 0.0 7e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ANTH PF07651.11 GAM25837.1 - 0.024 13.3 1.0 0.042 12.5 0.7 1.3 1 0 0 1 1 1 0 ANTH domain DUF651 PF04895.7 GAM25837.1 - 0.042 13.4 0.2 0.13 11.9 0.2 1.8 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF651) DUF3317 PF11779.3 GAM25837.1 - 0.16 11.4 2.2 0.32 10.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF3678 PF12435.3 GAM25837.1 - 1.6 8.3 6.1 0.47 10.0 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) NifQ PF04891.7 GAM25837.1 - 1.7 8.8 4.1 28 4.8 0.0 2.3 1 1 0 2 2 2 0 NifQ FdhE PF04216.7 GAM25837.1 - 2.8 7.5 5.2 4.9 6.7 3.6 1.5 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation Rootletin PF15035.1 GAM25837.1 - 3.6 7.5 17.3 1.4 8.8 3.4 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion AIM24 PF01987.12 GAM25838.1 - 1.8e-53 181.2 0.4 1.8e-53 181.2 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 BATS PF06968.8 GAM25838.1 - 0.056 13.2 0.2 0.49 10.2 0.0 2.4 3 0 0 3 3 3 0 Biotin and Thiamin Synthesis associated domain Ank PF00023.25 GAM25839.1 - 1e-66 217.5 13.3 5.4e-09 35.4 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat Ank_2 PF12796.2 GAM25839.1 - 1.2e-55 185.8 17.3 1.8e-14 53.8 0.6 5.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM25839.1 - 3.7e-44 144.3 10.7 1.4e-05 24.8 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAM25839.1 - 3.2e-40 135.8 2.7 1.4e-09 38.2 0.0 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM25839.1 - 1.9e-38 129.6 29.1 8.3e-10 38.5 0.0 9.0 3 1 6 9 9 9 7 Ankyrin repeats (many copies) F-box PF00646.28 GAM25839.1 - 9.6e-09 34.6 0.1 3.2e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM25839.1 - 1.8e-08 33.9 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like LOH1CR12 PF10158.4 GAM25840.1 - 0.0028 17.4 0.2 0.0058 16.4 0.2 1.4 1 0 0 1 1 1 1 Tumour suppressor protein Myotub-related PF06602.9 GAM25841.1 - 8.4e-59 199.1 0.3 2.5e-58 197.5 0.2 1.8 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.12 GAM25841.1 - 2.1e-36 125.3 0.0 5.9e-33 114.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.2 GAM25841.1 - 3.7e-36 122.1 37.1 3.2e-10 39.4 0.6 7.9 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) Pkinase PF00069.20 GAM25841.1 - 1.1e-32 113.2 0.0 2.5e-29 102.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.1 GAM25841.1 - 9.1e-23 79.7 34.3 3.8e-08 32.9 4.3 6.3 5 1 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 GAM25841.1 - 5.8e-14 49.9 28.7 0.12 12.4 0.1 11.8 11 0 0 11 11 10 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM25841.1 - 1.1e-08 33.8 22.7 2.4 8.7 0.0 10.6 10 0 0 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 GAM25841.1 - 2.3e-05 23.9 29.3 0.39 10.9 0.7 9.9 9 1 0 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 GAM25841.1 - 0.014 14.9 0.9 0.067 12.7 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeat DUF3439 PF11921.3 GAM25841.1 - 1.2 8.9 13.7 1.9 8.2 8.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM25841.1 - 1.2 8.8 24.8 0.26 11.0 14.3 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein MOR2-PAG1_C PF14225.1 GAM25842.1 - 4.1e-19 69.3 0.1 2.6e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 Cell morphogenesis C-terminal RGS PF00615.14 GAM25842.1 - 3e-07 30.5 0.0 1.2e-06 28.5 0.0 2.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RabGAP-TBC PF00566.13 GAM25843.1 - 6.6e-52 176.0 0.3 6.6e-52 176.0 0.2 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 GAM25843.1 - 1.8e-21 75.4 1.0 2.7e-11 42.8 0.5 2.9 2 0 0 2 2 2 2 GRAM domain EF-hand_7 PF13499.1 GAM25843.1 - 7e-10 38.8 2.8 2.6e-09 37.0 1.9 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM25843.1 - 4.8e-09 34.8 3.7 0.0018 17.4 0.3 3.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 GAM25843.1 - 6.1e-08 31.9 2.2 0.0051 16.5 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 GAM25843.1 - 0.00011 21.7 7.7 0.081 12.5 1.0 2.9 1 1 1 2 2 2 2 EF-hand domain pair EGF_2 PF07974.8 GAM25844.1 - 1.4e-05 25.1 26.3 0.0027 17.8 5.2 2.8 1 1 1 2 2 2 2 EGF-like domain EGF_2 PF07974.8 GAM25845.1 - 0.00018 21.5 26.6 0.056 13.6 5.4 2.7 1 1 1 2 2 2 2 EGF-like domain PGM_PMM_IV PF00408.15 GAM25845.1 - 0.038 13.9 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Rifin_STEVOR PF02009.11 GAM25845.1 - 5.6 6.5 8.3 9.4 5.7 5.8 1.3 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 GAM25845.1 - 6.9 6.3 12.1 16 5.1 8.4 1.7 1 0 0 1 1 1 0 TMEM154 protein family LRR_6 PF13516.1 GAM25846.1 - 2.2e-20 70.3 84.4 0.41 10.8 0.1 24.5 24 3 1 26 26 26 10 Leucine Rich repeat LRR_4 PF12799.2 GAM25846.1 - 2.9e-18 65.0 69.3 0.003 17.1 0.9 17.1 7 4 6 15 15 15 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM25846.1 - 3.4e-15 55.5 62.6 0.00032 20.3 4.2 12.5 10 3 3 13 13 13 9 Leucine rich repeat LRR_1 PF00560.28 GAM25846.1 - 0.00013 21.5 69.1 11 6.5 0.0 19.2 16 6 0 16 16 16 2 Leucine Rich Repeat DUF1699 PF08004.6 GAM25846.1 - 0.24 10.9 12.2 17 4.9 0.0 6.0 5 2 2 7 7 7 0 Protein of unknown function (DUF1699) AAA_28 PF13521.1 GAM25847.1 - 0.027 14.4 0.7 0.084 12.8 0.5 1.8 1 0 0 1 1 1 0 AAA domain Peptidase_M8 PF01457.11 GAM25848.1 - 9e-42 143.0 0.1 1.1e-41 142.8 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF3294 PF07957.6 GAM25849.1 - 0.00017 21.1 0.2 0.0002 20.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF3422 PF11902.3 GAM25849.1 - 0.0018 17.2 1.0 0.0023 16.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3422) DivIVA PF05103.8 GAM25849.1 - 0.11 12.4 1.3 0.16 11.9 0.9 1.3 1 0 0 1 1 1 0 DivIVA protein Nup88 PF10168.4 GAM25849.1 - 0.25 9.1 2.3 0.31 8.8 1.6 1.0 1 0 0 1 1 1 0 Nuclear pore component APG6 PF04111.7 GAM25849.1 - 0.35 9.8 2.0 0.43 9.5 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NAGLU PF05089.7 GAM25850.1 - 2.2e-137 457.2 10.7 3e-137 456.8 7.4 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAM25850.1 - 2.3e-66 223.9 7.2 3e-66 223.5 5.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAM25850.1 - 2.5e-16 59.1 0.0 6.8e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Pax2_C PF12403.3 GAM25850.1 - 0.087 12.4 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Paired-box protein 2 C terminal ABC_membrane PF00664.18 GAM25851.1 - 1.1e-49 169.3 28.4 1.1e-49 169.3 19.7 2.6 3 1 0 4 4 4 1 ABC transporter transmembrane region ABC_tran PF00005.22 GAM25851.1 - 1.7e-34 119.0 0.0 3.8e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM25851.1 - 1.1e-06 28.7 0.1 0.028 14.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 GAM25851.1 - 1.7e-06 27.4 0.9 0.00057 19.1 0.0 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM25851.1 - 0.0033 16.9 0.4 0.011 15.2 0.3 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 GAM25851.1 - 0.0048 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 GAM25851.1 - 0.008 14.8 0.1 0.19 10.2 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 GAM25851.1 - 0.025 13.9 0.3 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 GAM25851.1 - 0.078 13.7 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM25851.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 GAM25851.1 - 0.12 12.6 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 GAM25851.1 - 0.12 12.2 0.2 0.89 9.5 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 GAM25851.1 - 0.17 12.0 1.0 1.8 8.6 0.7 2.4 1 1 0 1 1 1 0 AAA domain MTP18 PF10558.4 GAM25851.1 - 5.4 6.8 9.9 2.5 7.9 0.5 2.9 2 1 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) DUF3391 PF11871.3 GAM25852.1 - 0.11 12.6 10.0 2.2 8.4 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4106 PF13388.1 GAM25852.1 - 0.26 10.1 17.4 0.021 13.7 6.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Pex14_N PF04695.8 GAM25852.1 - 0.86 9.6 8.4 0.06 13.3 2.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 GAM25852.1 - 2.4 6.2 28.4 2.6 6.1 19.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Actin PF00022.14 GAM25853.1 - 9.7e-162 537.8 0.0 1.1e-161 537.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM25853.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Presenilin PF01080.12 GAM25854.1 - 5e-94 315.3 9.2 1.2e-60 205.4 3.8 3.0 1 1 2 3 3 3 2 Presenilin Peptidase_A22B PF04258.8 GAM25854.1 - 0.00029 20.3 9.6 0.005 16.3 0.7 2.3 2 0 0 2 2 2 2 Signal peptide peptidase DUF3353 PF11833.3 GAM25854.1 - 0.091 12.2 0.1 0.091 12.2 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) Pex14_N PF04695.8 GAM25854.1 - 0.54 10.3 12.0 2.2 8.3 0.4 2.5 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 GAM25854.1 - 1.8 8.2 8.6 1.1 8.9 0.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) NUC173 PF08161.7 GAM25855.1 - 1.6e-56 190.8 0.0 7.1e-56 188.7 0.0 2.2 2 0 0 2 2 2 1 NUC173 domain FAD_binding_3 PF01494.14 GAM25857.1 - 8.2e-32 110.6 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF4470 PF14737.1 GAM25857.1 - 0.11 12.2 0.1 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Longin PF13774.1 GAM25858.1 - 2.5e-11 42.9 0.3 4.6e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2265 PF10023.4 GAM25858.1 - 0.04 13.0 0.3 0.074 12.1 0.1 1.5 1 1 0 1 1 1 0 Predicted aminopeptidase (DUF2265) HMG_box PF00505.14 GAM25859.1 - 8.6e-15 54.7 1.4 9.3e-15 54.6 1.0 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM25859.1 - 1e-11 44.9 0.6 1.1e-11 44.8 0.4 1.0 1 0 0 1 1 1 1 HMG-box domain DEAD PF00270.24 GAM25860.1 - 4e-19 68.7 0.1 4e-19 68.7 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM25860.1 - 9.1e-10 38.2 0.0 6.4e-09 35.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3244 PF11589.3 GAM25861.1 - 1.7e-16 59.7 10.4 0.22 11.2 0.0 10.2 11 0 0 11 11 11 7 Domain of unknown function (DUF3244) DUF2012 PF09430.5 GAM25861.1 - 1.6e-05 24.6 0.0 21 5.0 0.0 7.0 8 0 0 8 8 8 1 Protein of unknown function (DUF2012) DUF1395 PF07160.7 GAM25862.1 - 0.11 12.0 0.5 11 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DUF3523 PF12037.3 GAM25863.1 - 0.088 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) RasGEF PF00617.14 GAM25864.1 - 2.4e-65 219.8 1.2 1.6e-64 217.1 0.2 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAM25864.1 - 3.7e-28 97.6 2.3 1.4e-27 95.7 1.6 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_L18_c PF14204.1 GAM25864.1 - 0.12 12.9 2.1 0.23 12.0 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region YhhN PF07947.9 GAM25865.1 - 7.8e-36 123.1 18.9 1.2e-35 122.5 13.1 1.3 1 0 0 1 1 1 1 YhhN-like protein DUF373 PF04123.8 GAM25865.1 - 6.3 5.7 11.2 5.9 5.8 5.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) FNIP PF05725.7 GAM25866.1 - 5.1e-33 112.7 18.6 8.8e-12 44.7 0.1 7.0 6 1 2 8 8 8 6 FNIP Repeat KTI12 PF08433.5 GAM25867.1 - 1e-92 310.1 0.0 1.2e-92 310.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 GAM25867.1 - 2.6e-11 43.5 0.0 1e-10 41.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM25867.1 - 0.00017 20.7 0.5 0.0017 17.4 0.1 2.5 2 1 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 GAM25867.1 - 0.00028 21.6 0.0 0.00049 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM25867.1 - 0.0017 18.3 0.0 0.0074 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 GAM25867.1 - 0.0019 18.3 0.1 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 GAM25867.1 - 0.0021 18.3 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM25867.1 - 0.0071 15.2 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATP_bind_1 PF03029.12 GAM25867.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 GAM25867.1 - 0.04 13.6 0.0 0.41 10.4 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain AAA_10 PF12846.2 GAM25867.1 - 0.065 12.6 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 GAM25867.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM25867.1 - 0.088 12.7 0.6 8.6 6.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 GAM25867.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Pro_dh PF01619.13 GAM25868.1 - 1.7e-63 214.4 0.1 2.9e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase DUF912 PF06024.7 GAM25868.1 - 0.089 12.8 2.6 0.17 11.9 1.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ADH_zinc_N PF00107.21 GAM25869.1 - 2.6e-16 59.3 0.0 7.4e-16 57.8 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 GAM25869.1 - 4.1e-16 60.0 0.0 9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM25869.1 - 6.6e-12 45.1 0.5 2.4e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pox_A32 PF04665.7 GAM25869.1 - 0.041 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein adh_short PF00106.20 GAM25870.1 - 1.2e-19 70.8 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM25870.1 - 4.4e-08 33.1 0.0 7.3e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM25870.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NDT80_PhoG PF05224.7 GAM25871.1 - 1.2e-21 77.5 0.1 1.2e-21 77.5 0.1 3.9 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 GAM25871.1 - 8.3e-11 41.8 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.1 GAM25871.1 - 1.2e-07 30.5 0.1 1.2e-07 30.5 0.0 1.6 2 0 0 2 2 2 1 Myelin gene regulatory factor -C-terminal domain 1 ETRAMP PF09716.5 GAM25871.1 - 9.4e-06 25.4 0.2 9.4e-06 25.4 0.2 2.6 4 0 0 4 4 4 1 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.1 GAM25871.1 - 0.0067 15.8 0.6 0.19 11.1 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4366) DUF4337 PF14235.1 GAM25871.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4337) Herpes_US9 PF06072.6 GAM25871.1 - 0.29 11.0 0.2 0.7 9.7 0.1 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 WD40 PF00400.27 GAM25872.1 - 4.8e-38 127.6 18.5 5.4e-10 38.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 GAM25872.1 - 2.5e-28 97.7 2.0 5.9e-28 96.5 0.5 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 GAM25872.1 - 1.3e-05 25.0 0.5 0.00096 18.9 0.0 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.1 GAM25873.1 - 1.9e-12 46.8 6.2 0.029 14.5 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM25873.1 - 2.6e-10 39.9 10.1 0.022 14.4 0.0 5.1 3 2 2 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM25873.1 - 2.2e-07 30.3 2.5 0.31 10.8 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 GAM25873.1 - 0.0009 19.1 8.2 0.31 11.0 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM25873.1 - 0.12 12.5 6.1 2.5 8.3 0.0 4.5 5 1 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM25873.1 - 0.17 11.4 9.2 6.4 6.4 0.2 4.6 4 1 0 4 4 4 0 Kelch motif FNIP PF05725.7 GAM25874.1 - 2.4e-90 296.2 28.5 1.2e-15 57.1 0.3 10.7 8 2 4 12 12 12 11 FNIP Repeat XPG_N PF00752.12 GAM25875.1 - 2.2e-30 104.9 0.0 5e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAM25875.1 - 8.1e-28 96.3 0.0 1.8e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 GAM25875.1 - 1e-07 32.0 0.1 6.3e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF3231 PF11553.3 GAM25875.1 - 0.0076 15.7 0.2 0.71 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3231) NPBW PF15180.1 GAM25875.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Neuropeptides B and W Myelin_MBP PF01669.12 GAM25875.1 - 0.26 11.5 2.6 0.3 11.3 0.6 1.9 3 0 0 3 3 3 0 Myelin basic protein VPS9 PF02204.13 GAM25876.1 - 3.5e-34 116.9 1.2 7.3e-34 115.9 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ras PF00071.17 GAM25877.1 - 3.5e-64 215.0 0.3 4e-64 214.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM25877.1 - 1.4e-21 77.1 0.0 2.1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM25877.1 - 1.3e-18 66.8 0.2 1.6e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM25877.1 - 6e-07 28.8 0.0 7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM25877.1 - 4e-06 26.4 0.2 1e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM25877.1 - 4.4e-05 23.3 0.1 6.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 GAM25877.1 - 4.7e-05 22.6 0.0 7.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 GAM25877.1 - 0.00069 18.9 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA PF00004.24 GAM25877.1 - 0.0022 18.2 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 GAM25877.1 - 0.0084 16.4 0.3 0.068 13.4 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 GAM25877.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 GAM25877.1 - 0.018 13.7 1.9 1.6 7.2 0.2 2.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 GAM25877.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 GAM25877.1 - 0.022 13.9 0.1 0.038 13.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM25877.1 - 0.032 13.7 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 GAM25877.1 - 0.065 12.8 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RGP PF03214.8 GAM25877.1 - 0.065 11.9 0.0 0.093 11.4 0.0 1.3 1 1 0 1 1 1 0 Reversibly glycosylated polypeptide Septin PF00735.13 GAM25877.1 - 0.11 11.4 0.1 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 Septin ELFV_dehydrog_N PF02812.13 GAM25877.1 - 0.12 11.9 0.1 0.2 11.2 0.0 1.4 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ECH PF00378.15 GAM25878.1 - 8.4e-80 267.4 2.2 1e-79 267.1 1.5 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 GAM25878.1 - 2.3e-05 24.4 0.0 4.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 GAM25878.1 - 0.00047 19.9 0.3 0.038 13.7 0.0 2.6 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.11 GAM25878.1 - 0.022 13.5 0.0 0.057 12.1 0.0 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase PI3_PI4_kinase PF00454.22 GAM25879.1 - 4.4e-38 131.0 0.2 2.4e-37 128.6 0.1 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TFIIA PF03153.8 GAM25880.1 - 0.0078 16.1 25.4 0.011 15.6 17.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 GAM25880.1 - 1.1 7.4 24.3 1.5 7.0 16.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_viral_N PF00242.12 GAM25880.1 - 6.8 5.6 25.6 11 4.9 17.8 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SpoU_methylase PF00588.14 GAM25881.1 - 3.2e-27 95.1 0.0 6.5e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 GAM25881.1 - 0.00014 21.9 2.0 0.00078 19.5 0.0 2.9 3 0 0 3 3 3 1 RNA 2'-O ribose methyltransferase substrate binding Snf7 PF03357.16 GAM25882.1 - 3.9e-40 137.0 30.4 4.5e-40 136.8 21.1 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 GAM25882.1 - 0.019 14.3 6.4 0.025 13.9 4.4 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Phage_X PF05155.10 GAM25882.1 - 0.037 13.9 0.4 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 Phage X family Glyco_hydro_17 PF00332.13 GAM25882.1 - 0.037 13.0 2.2 0.044 12.8 1.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 AMP-binding_C_2 PF14535.1 GAM25882.1 - 0.51 10.4 4.7 0.23 11.5 1.1 2.0 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain DUF4037 PF13228.1 GAM25882.1 - 1.4 9.1 4.9 0.56 10.4 0.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4037) Cofilin_ADF PF00241.15 GAM25883.1 - 2.6e-29 101.6 0.0 6.4e-09 35.7 0.0 3.1 3 0 0 3 3 3 3 Cofilin/tropomyosin-type actin-binding protein PSD2 PF07624.6 GAM25883.1 - 0.0098 15.5 0.0 8.4 6.1 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1585) HATPase_c PF02518.21 GAM25884.1 - 8.1e-26 89.9 0.1 1.5e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM25884.1 - 6.6e-22 77.6 1.8 1.3e-17 63.8 0.2 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 GAM25884.1 - 1e-20 73.5 0.0 2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 GAM25884.1 - 3.9e-09 36.8 0.0 6.6e-08 32.8 0.0 2.8 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.1 GAM25884.1 - 1e-05 25.1 0.1 0.00079 19.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain FleQ PF06490.6 GAM25884.1 - 0.00027 21.0 0.3 0.26 11.4 0.0 2.8 2 0 0 2 2 2 2 Flagellar regulatory protein FleQ PAS_3 PF08447.6 GAM25884.1 - 0.00061 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold Cons_hypoth95 PF03602.10 GAM25884.1 - 0.00095 18.6 0.1 0.048 13.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Peptidase_M24 PF00557.19 GAM25885.1 - 3.2e-37 128.1 0.0 4.7e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAM25885.1 - 1.4e-26 93.5 0.0 6.3e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Ras PF00071.17 GAM25886.1 - 1.5e-53 180.4 0.6 1.9e-53 180.1 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM25886.1 - 3.1e-11 43.8 0.2 1e-10 42.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM25886.1 - 1e-09 37.9 0.2 1.3e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM25886.1 - 0.00025 20.5 0.1 0.00063 19.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Cmc1 PF08583.5 GAM25887.1 - 7.4e-05 22.4 4.5 0.0036 17.0 0.0 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 GAM25887.1 - 0.00011 22.1 2.2 0.00023 21.1 1.5 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Colipase-like PF15083.1 GAM25887.1 - 0.0029 17.5 2.7 0.0043 16.9 1.9 1.3 1 0 0 1 1 1 1 Colipase-like DUF3128 PF11326.3 GAM25887.1 - 0.042 13.9 0.5 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) UPF0203 PF05254.7 GAM25887.1 - 0.079 12.8 1.8 0.84 9.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) CHCH PF06747.8 GAM25887.1 - 0.14 12.1 12.3 2.6 8.0 1.0 3.8 3 1 0 3 3 3 0 CHCH domain UCR_hinge PF02320.11 GAM25887.1 - 2.8 7.9 6.6 9.7 6.2 0.2 2.6 2 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Plasmod_Pvs28 PF06247.6 GAM25887.1 - 3.7 7.0 8.6 0.25 10.9 1.9 1.8 1 1 1 2 2 2 0 Plasmodium ookinete surface protein Pvs28 Cellulase PF00150.13 GAM25888.1 - 3.8e-18 65.6 0.6 9e-18 64.4 0.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_32C PF08244.7 GAM25888.1 - 0.016 15.5 0.2 0.038 14.3 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal COG5 PF10392.4 GAM25889.1 - 9.3e-27 93.5 4.5 9.3e-27 93.5 3.1 3.5 3 1 1 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.6 GAM25889.1 - 1.4e-09 37.8 4.2 1.4e-09 37.8 2.9 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 GAM25889.1 - 9.6e-05 22.1 2.5 9.6e-05 22.1 1.7 3.2 3 0 0 3 3 3 1 Vps51/Vps67 IncA PF04156.9 GAM25889.1 - 0.017 14.6 4.8 0.057 13.0 3.3 1.9 1 0 0 1 1 1 0 IncA protein BBP1_C PF15272.1 GAM25889.1 - 0.18 11.3 8.0 0.46 10.0 4.6 2.4 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal PhoU PF01895.14 GAM25889.1 - 0.64 10.5 6.1 0.74 10.2 0.4 3.7 3 1 0 3 3 3 0 PhoU domain COG4 PF08318.7 GAM25890.1 - 5.5e-30 104.2 22.0 1.9e-29 102.4 15.2 2.1 1 1 0 1 1 1 1 COG4 transport protein DUF3019 PF11456.3 GAM25891.1 - 0.23 11.7 1.9 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3019) Acetyltransf_3 PF13302.1 GAM25892.1 - 7e-22 78.1 0.0 8.5e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM25892.1 - 4.4e-09 36.4 0.0 7.3e-09 35.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM25892.1 - 2.5e-07 30.7 0.1 4.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM25892.1 - 5.9e-07 29.4 0.0 9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM25892.1 - 2.3e-05 24.0 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Transthyretin PF00576.16 GAM25893.1 - 3.6e-35 120.2 0.5 4.3e-35 119.9 0.3 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 GAM25893.1 - 0.00017 21.5 0.2 0.00023 21.1 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.11 GAM25893.1 - 0.0045 16.8 1.4 0.0085 15.9 1.0 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) DUF4198 PF10670.4 GAM25893.1 - 0.026 14.5 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) EMP24_GP25L PF01105.19 GAM25893.1 - 0.047 13.4 0.1 0.056 13.1 0.1 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD phage_tail_N PF08400.5 GAM25893.1 - 0.077 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Prophage tail fibre N-terminal FbpA PF05833.6 GAM25895.1 - 4.3e-41 140.9 17.4 4.3e-41 140.9 12.0 3.6 3 1 1 4 4 4 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 GAM25895.1 - 4.5e-25 87.4 0.1 4.5e-25 87.4 0.1 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 GAM25895.1 - 8.5e-24 83.2 0.0 3.3e-23 81.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) LRR_4 PF12799.2 GAM25896.1 - 9.2e-33 111.3 45.0 1e-07 31.3 0.0 8.3 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM25896.1 - 1.8e-28 98.0 41.9 5.9e-10 38.7 1.6 6.4 4 2 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 GAM25896.1 - 5.2e-23 77.5 44.0 0.0011 18.6 0.3 12.0 11 2 1 12 12 12 8 Leucine Rich Repeat LRR_7 PF13504.1 GAM25896.1 - 2.8e-18 62.7 29.4 0.041 14.0 0.3 11.7 11 0 0 11 11 11 6 Leucine rich repeat LRR_6 PF13516.1 GAM25896.1 - 9.2e-10 37.5 39.1 0.49 10.6 0.1 11.0 9 2 2 11 11 11 5 Leucine Rich repeat Calponin PF00402.13 GAM25896.1 - 0.04 13.2 1.8 0.077 12.3 1.3 1.4 1 0 0 1 1 1 0 Calponin family repeat Filamin PF00630.14 GAM25896.1 - 0.068 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF2296 PF10058.4 GAM25897.1 - 8.6e-18 63.8 0.7 1.5e-17 63.0 0.5 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) ubiquitin PF00240.18 GAM25898.1 - 1.9e-08 33.5 0.1 1.9e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 GAM25898.1 - 2.5e-06 27.5 0.1 2.5e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 GAM25898.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 GAM25898.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RP-C_C PF11800.3 GAM25898.1 - 8.8 5.9 7.9 2.5 7.7 2.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region WD40 PF00400.27 GAM25899.1 - 1.3e-09 37.5 10.2 0.0075 16.1 0.0 4.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM25899.1 - 0.00043 19.1 6.6 0.0013 17.5 0.3 2.2 1 1 1 2 2 2 2 Nup133 N terminal like DUF2457 PF10446.4 GAM25899.1 - 1.1 7.9 15.9 1.9 7.1 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Defensin_big PF14862.1 GAM25899.1 - 1.5 8.9 3.5 3.6 7.7 2.4 1.5 1 0 0 1 1 1 0 Big defensin Complex1_LYR PF05347.10 GAM25900.1 - 0.00041 20.1 1.1 0.00051 19.7 0.8 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM25900.1 - 0.0029 17.7 0.8 0.0033 17.5 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like MIP PF00230.15 GAM25901.1 - 4.8e-31 107.9 13.5 6.4e-31 107.5 9.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein G-alpha PF00503.15 GAM25902.1 - 3.1e-121 404.7 4.7 3.6e-121 404.5 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM25902.1 - 3e-12 46.1 0.5 2.7e-08 33.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM25902.1 - 0.018 14.1 0.3 2.2 7.3 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM25902.1 - 0.03 13.7 0.1 1 8.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Malic_M PF03949.10 GAM25902.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Miro PF08477.8 GAM25902.1 - 0.061 13.8 0.1 16 6.0 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 GAM25902.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CBS PF00571.23 GAM25903.1 - 3e-28 97.3 2.7 6e-14 51.5 0.2 2.9 3 1 0 3 3 3 2 CBS domain DisA_N PF02457.11 GAM25903.1 - 0.016 14.3 0.1 0.033 13.3 0.0 1.7 1 1 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DUF3503 PF12011.3 GAM25903.1 - 0.057 13.1 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) RRN3 PF05327.6 GAM25904.1 - 0.018 13.2 3.4 0.02 13.0 2.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SprA-related PF12118.3 GAM25905.1 - 0.0054 16.1 25.6 0.0085 15.4 17.7 1.4 1 0 0 1 1 1 1 SprA-related family CDC27 PF09507.5 GAM25905.1 - 0.007 15.6 50.0 0.0086 15.3 34.6 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 CRT10 PF08728.5 GAM25905.1 - 4.7 5.0 12.7 5.4 4.8 8.8 1.1 1 0 0 1 1 1 0 CRT10 MIP-T3 PF10243.4 GAM25905.1 - 6.6 5.0 71.0 8.9 4.6 49.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Parvo_coat PF00740.13 GAM25905.1 - 6.9 5.5 10.4 10 4.9 7.2 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF3402 PF11882.3 GAM25906.1 - 1e-66 225.6 12.4 1e-62 212.5 6.3 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 GAM25906.1 - 5.9e-25 87.7 2.1 6.4e-25 87.5 0.2 1.9 2 1 0 2 2 2 1 N1221-like protein Frag1 PF10277.4 GAM25907.1 - 7.6e-41 139.9 14.9 8.8e-41 139.7 10.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tmemb_18A PF09771.4 GAM25907.1 - 5.9 6.8 6.0 0.36 10.7 0.1 2.0 3 0 0 3 3 3 0 Transmembrane protein 188 Ribosomal_L11 PF00298.14 GAM25908.1 - 6.2e-13 48.6 0.7 1e-12 47.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 GAM25908.1 - 3.5e-12 45.5 0.1 5.6e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain AT_hook PF02178.14 GAM25909.1 - 0.085 12.5 47.2 0.52 10.1 3.7 4.6 4 0 0 4 4 4 0 AT hook motif Hemerythrin PF01814.18 GAM25910.1 - 1.1e-11 44.9 0.1 2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PhaP_Bmeg PF09602.5 GAM25910.1 - 0.0016 18.2 1.2 0.0022 17.8 0.8 1.2 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Mating_N PF12731.2 GAM25910.1 - 0.016 15.1 0.0 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF2493 PF10686.4 GAM25910.1 - 0.038 13.5 0.1 0.072 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) SseB_C PF14581.1 GAM25910.1 - 0.051 13.4 0.5 1 9.2 0.0 2.1 2 0 0 2 2 2 0 SseB protein C-terminal domain Lant_dehyd_C PF04738.8 GAM25910.1 - 0.055 11.6 0.1 0.079 11.1 0.1 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus GvpL_GvpF PF06386.6 GAM25910.1 - 0.08 12.5 0.2 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DIX PF00778.12 GAM25910.1 - 0.085 12.5 0.5 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 DIX domain CENP-H PF05837.7 GAM25910.1 - 0.15 12.2 0.9 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spectrin PF00435.16 GAM25910.1 - 0.22 11.8 1.7 2.1 8.7 0.3 2.6 2 1 1 3 3 3 0 Spectrin repeat BLOC1_2 PF10046.4 GAM25910.1 - 0.6 10.2 2.9 5.1 7.3 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sod_Cu PF00080.15 GAM25911.1 - 6.6e-25 87.9 0.6 3.9e-22 78.9 0.1 2.5 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.15 GAM25912.1 - 3.5e-28 98.5 0.6 2e-22 79.8 0.1 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) SET PF00856.23 GAM25914.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 SET domain DUF3446 PF11928.3 GAM25914.1 - 0.4 10.9 18.4 2.9 8.1 5.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) zf-FCS PF06467.9 GAM25914.1 - 0.56 9.8 0.1 0.56 9.8 0.1 3.9 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif SSP160 PF06933.6 GAM25914.1 - 9.7 4.0 18.9 0.12 10.2 7.3 1.8 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Glyco_hydro_47 PF01532.15 GAM25915.1 - 7.1e-133 443.5 0.0 8.2e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FNIP PF05725.7 GAM25916.1 - 4.3e-35 119.3 23.7 3.9e-13 49.1 0.0 7.0 5 2 1 6 6 6 6 FNIP Repeat LRR_4 PF12799.2 GAM25916.1 - 0.049 13.2 0.2 0.049 13.2 0.1 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM25916.1 - 0.074 13.1 3.3 16 6.0 0.0 5.2 3 2 0 3 3 3 0 Leucine Rich Repeat Ank_2 PF12796.2 GAM25917.1 - 2.5e-12 46.9 4.5 0.00012 22.3 0.0 5.2 3 3 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25917.1 - 9.7e-07 29.1 3.6 1.9 9.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM25917.1 - 4.5e-06 26.7 1.8 5.8 7.3 0.0 6.1 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM25917.1 - 3.4e-05 23.6 9.8 1.7 9.1 0.0 7.0 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.25 GAM25917.1 - 4.2e-05 23.1 4.2 2.9 7.8 0.1 5.6 6 0 0 6 6 6 2 Ankyrin repeat DUF1477 PF07346.6 GAM25917.1 - 0.00083 19.3 0.7 0.04 13.9 0.0 3.8 3 2 1 4 4 4 1 Protein of unknown function (DUF1477) FNIP PF05725.7 GAM25918.1 - 8.4e-71 233.7 28.0 5.1e-13 48.7 1.4 8.2 3 3 5 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 GAM25918.1 - 2.9e-14 52.8 5.7 4.6e-06 26.3 0.2 3.2 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) ParBc_2 PF08857.6 GAM25918.1 - 0.08 12.7 0.1 1.3e+02 2.3 0.0 4.8 5 2 1 6 6 6 0 Putative ParB-like nuclease FNIP PF05725.7 GAM25919.1 - 4e-78 257.1 38.0 1.1e-11 44.4 0.1 10.3 7 2 4 11 11 11 11 FNIP Repeat DUF1769 PF08588.5 GAM25919.1 - 1.8e-08 34.2 4.8 0.058 13.3 0.0 6.7 4 2 3 7 7 7 4 Protein of unknown function (DUF1769) Complex1_LYR_1 PF13232.1 GAM25921.1 - 8.2e-07 29.1 0.5 1.5e-06 28.2 0.4 1.5 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM25921.1 - 3.4e-05 23.5 0.1 5.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zf-UBR PF02207.15 GAM25922.1 - 4.3e-18 64.7 13.2 4.3e-18 64.7 9.2 3.2 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 GAM25922.1 - 4.8e-11 42.2 0.1 1.2e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS G-patch_2 PF12656.2 GAM25922.1 - 0.017 14.9 0.1 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site CwfJ_C_1 PF04677.10 GAM25923.1 - 2.1e-26 91.9 0.4 4.3e-26 90.9 0.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 GAM25923.1 - 5.3e-13 49.2 1.1 5.3e-13 49.2 0.8 3.1 3 1 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 RFC1 PF08519.7 GAM25923.1 - 0.032 13.9 0.1 0.81 9.4 0.0 2.8 2 1 0 2 2 2 0 Replication factor RFC1 C terminal domain VWA PF00092.23 GAM25925.1 - 2.1e-12 47.1 0.1 3.6e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 GAM25925.1 - 3.5e-08 33.7 0.1 6.4e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain IIGP PF05049.8 GAM25925.1 - 0.0013 17.6 0.3 0.92 8.2 0.0 2.3 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) DUF815 PF05673.8 GAM25925.1 - 0.0022 16.9 0.0 0.0051 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 GAM25925.1 - 0.0032 16.9 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 GAM25925.1 - 0.0043 16.7 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase VWA_CoxE PF05762.9 GAM25925.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF258 PF03193.11 GAM25925.1 - 0.014 14.6 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 GAM25925.1 - 0.017 14.6 0.1 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain vWA-TerF-like PF10138.4 GAM25925.1 - 0.018 14.8 0.0 0.091 12.5 0.0 2.0 2 0 0 2 2 2 0 vWA found in TerF C terminus FtsK_SpoIIIE PF01580.13 GAM25925.1 - 0.022 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 GAM25925.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAM25925.1 - 0.022 14.5 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 GAM25925.1 - 0.028 13.5 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 GAM25925.1 - 0.031 14.4 0.0 0.095 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 GAM25925.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 GAM25925.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 GAM25925.1 - 0.081 12.1 0.2 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 GAM25925.1 - 0.12 12.5 0.1 0.81 9.8 0.0 2.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 GAM25925.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DZR PF12773.2 GAM25925.1 - 0.44 10.4 28.0 4.7e+03 -2.5 19.3 3.1 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 GAM25925.1 - 0.61 9.6 29.6 0.45 10.0 1.8 4.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 GAM25925.1 - 6.2 6.1 35.0 0.08 12.1 1.6 4.4 3 1 0 3 3 3 0 zinc-ribbon domain AAA_16 PF13191.1 GAM25927.1 - 0.12 12.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 GAM25927.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC1 PF03109.11 GAM25928.1 - 8.5e-32 109.6 0.1 1.5e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 GAM25928.1 - 0.008 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) ApoC-I PF04691.7 GAM25928.1 - 0.025 14.2 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Oxidored_q1_N PF00662.15 GAM25928.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Pap_E4 PF02711.9 GAM25928.1 - 2.6 8.9 6.6 0.2 12.5 0.4 2.2 3 0 0 3 3 3 0 E4 protein Zn_Tnp_IS1595 PF12760.2 GAM25929.1 - 0.0009 18.9 20.5 0.068 12.9 3.6 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 GAM25929.1 - 0.0053 16.5 8.8 0.32 10.8 3.1 2.4 2 0 0 2 2 2 2 PhnA Zinc-Ribbon DUF2318 PF10080.4 GAM25929.1 - 0.049 13.3 3.7 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Ribosomal_L37ae PF01780.14 GAM25929.1 - 0.46 10.3 12.0 0.58 10.0 1.2 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family Rpr2 PF04032.11 GAM25929.1 - 7 6.5 15.2 26 4.7 0.6 3.7 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GRIP PF01465.15 GAM25930.1 - 0.00038 19.9 0.6 0.0015 17.9 0.0 2.4 2 0 0 2 2 2 1 GRIP domain Reo_sigmaC PF04582.7 GAM25930.1 - 0.0042 16.3 4.2 0.0042 16.3 2.9 2.1 2 1 0 3 3 3 1 Reovirus sigma C capsid protein DUF641 PF04859.7 GAM25930.1 - 0.012 15.3 2.5 0.012 15.3 1.7 6.3 2 1 5 7 7 7 0 Plant protein of unknown function (DUF641) DUF2087 PF09860.4 GAM25930.1 - 0.076 12.7 2.0 0.12 12.1 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) P5CR_dimer PF14748.1 GAM25931.1 - 1.9e-26 92.1 1.0 3.6e-26 91.2 0.7 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 GAM25931.1 - 1.2e-16 60.9 0.1 3e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 GAM25931.1 - 1.5e-05 24.7 2.0 0.00011 21.9 1.4 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 GAM25931.1 - 0.00021 20.7 0.1 0.001 18.5 0.0 2.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 GAM25931.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 GAM25931.1 - 0.0028 17.0 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 GAM25931.1 - 0.008 15.3 0.0 0.022 13.9 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM25931.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain Troponin-I_N PF11636.3 GAM25931.1 - 4.8 6.9 7.8 0.25 11.0 1.5 1.8 2 0 0 2 2 2 0 Troponin I residues 1-32 FNIP PF05725.7 GAM25932.1 - 1.4e-80 264.9 19.9 6.4e-13 48.4 0.0 8.4 4 3 6 10 10 10 9 FNIP Repeat Tecti-min-caps PF09300.5 GAM25932.1 - 0.023 14.4 2.8 74 3.2 0.0 4.9 4 1 1 5 5 5 0 Tectiviridae, minor capsid zf-RING_2 PF13639.1 GAM25933.1 - 1.6e-12 47.0 13.1 1.6e-12 47.0 9.1 2.4 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 GAM25933.1 - 3.2e-08 33.5 8.2 9.4e-08 32.0 5.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM25933.1 - 1.9e-06 27.7 10.1 1.9e-06 27.7 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM25933.1 - 6.5e-06 25.7 8.8 6.5e-06 25.7 6.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM25933.1 - 1.1e-05 25.0 7.8 1.1e-05 25.0 5.4 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM25933.1 - 1.6e-05 24.4 9.8 1.6e-05 24.4 6.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SSP160 PF06933.6 GAM25933.1 - 2.6e-05 22.4 9.1 2.6e-05 22.4 6.3 2.1 3 0 0 3 3 3 1 Special lobe-specific silk protein SSP160 Mucin PF01456.12 GAM25933.1 - 0.0021 17.8 14.3 0.0021 17.8 9.9 2.9 3 0 0 3 3 3 1 Mucin-like glycoprotein DUF3439 PF11921.3 GAM25933.1 - 0.0079 15.9 10.8 0.0079 15.9 7.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) zf-Apc11 PF12861.2 GAM25933.1 - 0.0092 15.7 5.4 0.025 14.4 3.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Pex14_N PF04695.8 GAM25933.1 - 0.044 13.8 0.1 0.044 13.8 0.1 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SCIMP PF15050.1 GAM25933.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.0 3 1 0 3 3 2 0 SCIMP protein FANCL_C PF11793.3 GAM25933.1 - 0.97 9.4 10.5 15 5.6 7.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain SoxE PF06525.6 GAM25933.1 - 1.9 7.6 13.1 4.8 6.3 9.1 1.6 1 0 0 1 1 1 0 Sulfocyanin (SoxE) HEAT PF02985.17 GAM25934.1 - 4.8e-49 160.0 18.2 0.00057 19.7 0.0 13.4 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 GAM25934.1 - 1.3e-38 131.1 0.4 2.9e-07 30.6 0.0 6.3 2 1 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 GAM25934.1 - 5.7e-12 45.7 7.7 0.039 14.4 0.0 8.6 9 2 1 10 10 9 2 HEAT-like repeat Arm PF00514.18 GAM25934.1 - 2.5e-10 39.7 0.3 0.058 13.2 0.0 6.8 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 GAM25934.1 - 5.3e-10 39.5 1.9 0.31 11.4 0.0 7.0 4 1 4 8 8 8 2 Vacuolar 14 Fab1-binding region Granulin PF00396.13 GAM25934.1 - 1.6e-09 37.6 21.5 1.6e-09 37.6 14.9 2.3 2 0 0 2 2 2 1 Granulin Adaptin_N PF01602.15 GAM25934.1 - 2.8e-09 35.8 8.6 0.00019 19.9 0.3 4.0 2 1 2 4 4 4 4 Adaptin N terminal region CLASP_N PF12348.3 GAM25934.1 - 3.7e-09 36.2 2.4 0.00012 21.5 0.0 5.2 3 2 2 5 5 5 2 CLASP N terminal Cnd1 PF12717.2 GAM25934.1 - 0.0016 18.3 1.1 0.12 12.2 0.0 3.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 tRNA-synt_His PF13393.1 GAM25934.1 - 0.028 13.4 0.4 0.15 11.0 0.1 2.2 2 1 0 2 2 2 0 Histidyl-tRNA synthetase TFCD_C PF12612.3 GAM25934.1 - 0.037 13.4 1.3 9.4 5.6 0.0 3.7 2 1 0 3 3 3 0 Tubulin folding cofactor D C terminal CDC50 PF03381.10 GAM25935.1 - 2.8e-88 295.7 0.0 6.3e-88 294.5 0.0 1.6 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family IncA PF04156.9 GAM25935.1 - 0.18 11.4 0.5 3.9 7.0 0.3 2.1 2 0 0 2 2 2 0 IncA protein Ras PF00071.17 GAM25936.1 - 2.1e-28 98.7 0.0 5.6e-23 81.1 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 GAM25936.1 - 4.8e-06 27.0 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM25936.1 - 1.3e-05 24.4 0.0 3.2e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Herpes_capsid PF06112.6 GAM25936.1 - 0.011 15.7 18.2 0.016 15.2 12.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Apt1 PF10351.4 GAM25936.1 - 0.021 13.7 9.3 0.022 13.6 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DDHD PF02862.12 GAM25936.1 - 0.032 14.0 4.6 0.034 13.9 3.2 1.1 1 0 0 1 1 1 0 DDHD domain MMR_HSR1 PF01926.18 GAM25936.1 - 0.055 13.4 0.0 0.096 12.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sec3_C PF09763.4 GAM25936.1 - 0.28 9.2 9.2 0.32 9.0 6.4 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Pex14_N PF04695.8 GAM25936.1 - 0.44 10.5 11.4 0.67 10.0 7.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 GAM25936.1 - 0.51 8.2 20.4 0.63 7.9 14.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 GAM25936.1 - 1.5 7.0 16.8 1.6 6.9 11.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 GAM25936.1 - 1.6 7.8 12.3 1.8 7.7 8.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bul1_C PF04426.7 GAM25936.1 - 3.4 6.7 10.5 4.6 6.3 7.3 1.1 1 0 0 1 1 1 0 Bul1 C terminus Herpes_DNAp_acc PF04929.7 GAM25936.1 - 3.8 6.3 14.2 4.8 6.0 9.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MATH PF00917.21 GAM25937.1 - 3e-40 137.1 34.3 2.5e-14 53.5 2.6 5.3 5 0 0 5 5 5 4 MATH domain USP7_ICP0_bdg PF12436.3 GAM25937.1 - 1.3e-35 122.8 0.1 1.3e-35 122.8 0.1 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Ubiquitin_2 PF14560.1 GAM25937.1 - 0.019 15.2 0.7 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-like domain DUF4175 PF13779.1 GAM25937.1 - 7.5 4.1 27.2 10 3.6 18.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) WD40 PF00400.27 GAM25939.1 - 1.3e-24 85.1 0.8 4e-08 32.8 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 GAM25939.1 - 0.0053 16.2 0.8 0.011 15.2 0.0 2.0 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 GAM25939.1 - 0.027 12.6 6.3 0.7 7.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 LCD1 PF09798.4 GAM25939.1 - 0.15 10.0 5.1 0.2 9.5 3.6 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein CDC45 PF02724.9 GAM25939.1 - 0.47 8.4 12.0 0.036 12.1 2.5 2.1 2 0 0 2 2 2 0 CDC45-like protein PP28 PF10252.4 GAM25940.1 - 3.2e-16 59.1 15.1 3.2e-16 59.1 10.5 2.2 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 DUF16 PF01519.11 GAM25940.1 - 0.81 9.9 9.1 1.3 9.3 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 CAF-1_p150 PF11600.3 GAM25940.1 - 1.5 8.1 30.1 0.055 12.8 17.0 1.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DRY_EERY PF09750.4 GAM25940.1 - 2.1 8.4 11.5 0.26 11.4 4.9 1.7 2 0 0 2 2 2 0 Alternative splicing regulator RXT2_N PF08595.6 GAM25940.1 - 6.7 6.4 16.2 0.047 13.4 3.9 2.2 1 1 1 2 2 2 0 RXT2-like, N-terminal APG6 PF04111.7 GAM25940.1 - 7.8 5.4 10.7 11 4.9 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ACPS PF01648.15 GAM25941.1 - 0.0058 16.4 1.7 0.0073 16.1 1.1 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Metallothi_Euk2 PF12809.2 GAM25941.1 - 0.037 14.4 2.0 0.042 14.2 1.4 1.3 1 1 0 1 1 1 0 Eukaryotic metallothionein CHCH PF06747.8 GAM25941.1 - 0.039 13.8 3.3 4.5 7.3 0.2 2.6 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 GAM25941.1 - 0.044 13.5 5.8 0.07 12.9 4.0 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 GAM25941.1 - 1 9.5 6.1 0.33 11.1 2.0 1.8 1 1 1 2 2 2 0 GCK domain NDUF_B7 PF05676.8 GAM25941.1 - 4.4 6.7 9.1 0.54 9.7 3.7 1.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Y_phosphatase PF00102.22 GAM25942.1 - 3.8e-72 242.4 2.1 1.1e-35 123.1 0.5 2.2 1 1 1 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 GAM25942.1 - 6.8e-06 25.7 0.0 1.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM25942.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAM25942.1 - 0.0013 19.0 0.9 0.0026 18.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF4611 PF15387.1 GAM25942.1 - 0.16 12.1 6.5 0.86 9.7 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 GAM25942.1 - 2.4 7.3 9.1 8 5.6 6.7 1.6 2 0 0 2 2 2 0 NOA36 protein FimP PF09766.4 GAM25942.1 - 8.2 5.3 15.1 1.7 7.6 0.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein Kelch_6 PF13964.1 GAM25943.1 - 1.2e-08 34.7 2.9 0.047 13.8 0.1 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 GAM25943.1 - 1.4e-07 30.9 0.3 0.0013 18.2 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 GAM25943.1 - 9.4e-06 25.3 0.7 0.021 14.5 0.0 3.7 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM25943.1 - 0.00044 20.3 0.6 0.93 9.7 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM25943.1 - 0.029 14.1 0.8 8.3 6.3 0.1 3.3 3 0 0 3 3 3 0 Kelch motif Kelch_5 PF13854.1 GAM25943.1 - 0.073 13.0 6.6 0.26 11.2 0.0 3.4 4 0 0 4 4 4 0 Kelch motif IPPT PF01715.12 GAM25944.1 - 6.6e-55 185.8 0.0 9.8e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 IPP transferase IPT PF01745.11 GAM25944.1 - 5.8e-07 28.9 0.3 2.7e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 GAM25944.1 - 0.0056 17.4 0.1 0.014 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 GAM25944.1 - 0.045 13.0 0.1 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_33 PF13671.1 GAM25944.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain HSBP1 PF06825.7 GAM25945.1 - 2.9e-17 61.9 2.6 3.9e-17 61.5 1.8 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2130 PF09903.4 GAM25945.1 - 0.021 13.5 0.1 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) SF-assemblin PF06705.6 GAM25945.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin BCNT PF07572.7 GAM25946.1 - 6.6e-16 58.0 2.6 6.6e-16 58.0 1.8 3.3 2 1 0 2 2 2 1 Bucentaur or craniofacial development Hid1 PF12722.2 GAM25946.1 - 2 6.0 15.6 2.6 5.6 10.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3c_N PF05470.7 GAM25946.1 - 2.2 6.2 22.1 3.4 5.6 15.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Methyltransf_31 PF13847.1 GAM25947.1 - 9.5e-12 44.7 0.0 3.3e-11 42.9 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM25947.1 - 1.5e-08 35.2 0.0 3e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM25947.1 - 2.7e-08 34.0 0.0 6.2e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM25947.1 - 5.8e-07 29.9 0.0 1.4e-06 28.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM25947.1 - 2.7e-06 27.2 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM25947.1 - 3e-05 24.4 0.0 8.6e-05 22.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM25947.1 - 0.0011 18.9 0.0 0.0048 16.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain TPMT PF05724.6 GAM25947.1 - 0.0031 16.9 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 GAM25947.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.6 GAM25947.1 - 0.033 12.8 0.0 0.045 12.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DUF43 PF01861.11 GAM25947.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 RNA_pol_Rbc25 PF08292.7 GAM25948.1 - 4.1e-32 110.9 0.3 4.1e-32 110.9 0.2 2.0 3 0 0 3 3 3 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 GAM25948.1 - 4.2e-12 46.0 0.0 8.4e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 GAM25948.1 - 1.3 9.1 4.0 3.5 7.7 0.0 3.2 4 0 0 4 4 4 0 S1 RNA binding domain Nop14 PF04147.7 GAM25948.1 - 8.5 4.1 13.7 11 3.8 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family PUF PF00806.14 GAM25949.1 - 4.4e-37 123.4 20.9 2.9e-06 26.4 0.3 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF445 PF04286.7 GAM25949.1 - 0.00068 19.2 12.3 0.001 18.6 1.4 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF445) Tenui_NCP PF04876.7 GAM25949.1 - 0.0031 17.0 2.3 0.015 14.8 0.5 2.8 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein DUF2363 PF10155.4 GAM25949.1 - 7.3 6.5 11.8 0.27 11.1 1.8 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) ATP-grasp_2 PF08442.5 GAM25950.1 - 6e-75 251.0 0.1 1.1e-74 250.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 GAM25950.1 - 4.2e-27 94.6 1.2 7.3e-27 93.8 0.9 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 GAM25950.1 - 5.1e-10 38.9 0.0 8.9e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 GAM25950.1 - 6.4e-05 22.6 0.6 0.0021 17.6 0.0 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.1 GAM25950.1 - 0.0056 16.2 0.1 0.024 14.2 0.1 2.0 1 1 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_4 PF13535.1 GAM25950.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RasGEF PF00617.14 GAM25951.1 - 7.8e-58 195.3 1.5 3.2e-57 193.3 1.0 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM25951.1 - 2.4e-18 66.1 1.5 1.1e-17 64.0 1.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif Mad3_BUB1_I PF08311.7 GAM25951.1 - 0.0039 16.9 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 DUF2672 PF10878.3 GAM25951.1 - 0.14 11.9 2.1 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) Bacteroid_pep PF14406.1 GAM25952.1 - 0.17 12.0 0.8 0.22 11.7 0.5 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes tRNA-synt_His PF13393.1 GAM25953.1 - 7.3e-50 169.7 0.0 9.2e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 GAM25953.1 - 9e-18 64.4 0.0 2.1e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM25953.1 - 1.2e-13 50.8 0.2 2.7e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 GAM25953.1 - 1.2e-05 24.2 0.0 0.00035 19.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 GAM25953.1 - 0.073 12.2 0.2 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Pkinase PF00069.20 GAM25955.1 - 2.7e-55 187.3 0.0 5.9e-55 186.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25955.1 - 1.3e-53 181.7 0.0 2.1e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 GAM25955.1 - 2.3e-31 107.9 2.3 1.1e-12 48.0 0.5 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM25955.1 - 3.1e-28 96.1 0.9 2.8e-06 26.8 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAM25955.1 - 2.3e-23 82.1 1.8 6e-08 33.0 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM25955.1 - 9.5e-20 70.1 2.2 4.2e-06 26.8 0.1 5.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM25955.1 - 5.7e-19 66.3 1.7 0.0038 17.3 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat GRAM PF02893.15 GAM25955.1 - 2e-13 49.6 0.2 4.4e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 GRAM domain C1_1 PF00130.17 GAM25955.1 - 3.2e-11 42.7 4.5 7.7e-11 41.5 3.1 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 GAM25955.1 - 0.00034 20.2 2.3 0.0008 19.0 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 APH PF01636.18 GAM25955.1 - 0.013 15.2 0.1 0.95 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family bPH_3 PF14470.1 GAM25955.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain PHD PF00628.24 GAM25955.1 - 0.38 10.4 3.4 1.2 8.9 2.4 1.8 1 0 0 1 1 1 0 PHD-finger Rep_fac-A_C PF08646.5 GAM25956.1 - 1.9e-10 40.6 0.4 1.9e-10 40.6 0.3 3.3 4 0 0 4 4 4 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 GAM25956.1 - 1.1e-06 28.4 0.0 0.0093 15.8 0.0 3.1 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain POT1 PF02765.12 GAM25956.1 - 0.00063 19.6 1.2 0.0062 16.4 0.3 2.8 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DUF223 PF02721.9 GAM25956.1 - 0.0083 16.1 0.0 0.032 14.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF223 Med3 PF11593.3 GAM25956.1 - 0.035 13.3 12.6 0.071 12.3 8.7 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4101 PF13355.1 GAM25956.1 - 0.91 9.9 9.9 0.17 12.3 3.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4101) WH1 PF00568.18 GAM25957.1 - 2.8e-19 68.8 0.0 4.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 GAM25957.1 - 3.1e-09 36.1 0.0 1e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 WH2 motif VASP_tetra PF08776.6 GAM25957.1 - 2e-07 30.2 0.5 3e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 VASP tetramerisation domain DBC1 PF14443.1 GAM25958.1 - 7.5e-35 119.2 0.0 1.8e-34 118.0 0.0 1.6 1 0 0 1 1 1 1 DBC1 AAA_11 PF13086.1 GAM25959.1 - 1.5e-30 106.4 0.0 3.4e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 GAM25959.1 - 1.2e-26 93.3 0.0 4.4e-26 91.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM25959.1 - 2e-09 37.0 0.0 5.4e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAM25959.1 - 6e-06 25.9 0.0 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 GAM25959.1 - 8.4e-05 22.4 0.1 0.00068 19.5 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM25959.1 - 0.00017 21.0 0.0 0.00065 19.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 GAM25959.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 GAM25959.1 - 0.00076 18.5 0.2 0.015 14.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 GAM25959.1 - 0.0046 17.0 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.24 GAM25959.1 - 0.011 15.9 0.0 0.035 14.3 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM25959.1 - 0.025 14.5 0.0 0.09 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.13 GAM25959.1 - 0.027 13.9 0.0 1.4 8.3 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 GAM25959.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein RecA PF00154.16 GAM25959.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_17 PF13207.1 GAM25959.1 - 0.14 12.9 0.3 1.4 9.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 GAM25959.1 - 0.14 11.5 0.4 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 GAM25959.1 - 0.29 11.4 0.1 0.29 11.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain ATP-synt_D PF01813.12 GAM25960.1 - 1.6e-65 220.3 5.9 2.5e-65 219.7 4.1 1.3 1 0 0 1 1 1 1 ATP synthase subunit D PQQ_2 PF13360.1 GAM25961.1 - 1e-05 25.1 0.2 4.7e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 PQQ-like domain EB PF01683.13 GAM25961.1 - 0.4 10.7 20.5 0.19 11.7 4.3 2.8 1 1 1 2 2 2 0 EB module DSL PF01414.14 GAM25961.1 - 0.53 10.3 23.2 0.35 10.9 11.7 2.9 2 0 0 2 2 2 0 Delta serrate ligand HSP70 PF00012.15 GAM25962.1 - 2.4e-99 332.9 8.1 2.3e-95 319.7 0.1 3.2 2 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 GAM25962.1 - 0.0082 14.7 0.0 0.017 13.7 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein EF-hand_7 PF13499.1 GAM25963.1 - 5.8e-21 74.4 5.4 2.2e-11 43.7 0.5 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM25963.1 - 1.1e-20 71.3 12.1 3e-06 26.1 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 GAM25963.1 - 7.8e-19 65.8 5.9 1.2e-05 24.7 0.1 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAM25963.1 - 4.6e-15 54.9 9.2 1.7e-05 24.3 0.6 4.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM25963.1 - 1.2e-14 52.8 13.7 9.2e-06 24.7 0.4 5.3 5 0 0 5 5 5 4 EF hand SPARC_Ca_bdg PF10591.4 GAM25963.1 - 1.3e-06 28.4 0.1 0.0064 16.5 0.0 2.8 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAM25963.1 - 1.3e-05 24.8 1.6 0.043 13.5 0.0 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 GAM25963.1 - 0.0002 20.9 3.2 1.9 8.1 0.2 4.1 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 GAM25963.1 - 0.0094 15.8 0.0 0.1 12.5 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain RCC1 PF00415.13 GAM25964.1 - 7.9e-35 118.8 6.8 6.7e-08 32.6 0.0 4.8 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM25964.1 - 6.9e-07 28.7 9.0 9.8e-05 21.8 0.4 5.6 4 2 1 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat DUF1120 PF06551.7 GAM25964.1 - 0.045 14.0 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1120) AlaDh_PNT_C PF01262.16 GAM25964.1 - 0.072 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sina PF03145.11 GAM25965.1 - 2.7e-08 33.7 3.0 4.3e-08 33.0 2.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family Nucleoplasmin PF03066.10 GAM25965.1 - 0.00023 20.6 11.2 0.0005 19.5 7.8 1.7 1 0 0 1 1 1 1 Nucleoplasmin CDC45 PF02724.9 GAM25965.1 - 0.011 13.7 12.5 0.014 13.4 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 GAM25965.1 - 0.13 10.5 2.0 0.14 10.4 1.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TLP-20 PF06088.6 GAM25965.1 - 0.34 10.5 4.7 0.7 9.5 3.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RXT2_N PF08595.6 GAM25965.1 - 0.35 10.6 10.7 0.76 9.5 7.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Prothymosin PF03247.9 GAM25965.1 - 0.41 10.7 30.6 0.05 13.7 18.1 1.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family VID27 PF08553.5 GAM25965.1 - 0.43 8.7 10.9 0.63 8.1 7.6 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 GAM25965.1 - 0.57 8.0 21.4 0.71 7.7 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family GOLD_2 PF13897.1 GAM25965.1 - 0.58 10.3 4.1 1.2 9.3 2.9 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2457 PF10446.4 GAM25965.1 - 0.86 8.2 33.3 1.6 7.3 23.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 GAM25965.1 - 0.98 7.8 19.9 1.5 7.2 13.8 1.2 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 GAM25965.1 - 1.1 6.9 9.5 1.5 6.6 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 GAM25965.1 - 1.2 8.4 11.5 2.2 7.6 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 GAM25965.1 - 2.1 7.8 19.4 3.8 6.9 13.4 1.4 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.3 GAM25965.1 - 3.1 7.6 21.0 6 6.7 14.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.11 GAM25965.1 - 3.2 6.6 13.5 3.7 6.4 8.2 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit ANAPC15 PF15243.1 GAM25965.1 - 3.4 7.8 19.7 8.3 6.5 13.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Upf2 PF04050.9 GAM25965.1 - 4.1 7.1 19.2 8.1 6.1 13.3 1.5 1 0 0 1 1 1 0 Up-frameshift suppressor 2 CENP-B_dimeris PF09026.5 GAM25965.1 - 4.6 7.5 27.6 10 6.4 19.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FYDLN_acid PF09538.5 GAM25965.1 - 7.1 7.2 26.9 7.9 7.1 12.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ank_2 PF12796.2 GAM25966.1 - 2.9e-09 37.1 10.9 0.0047 17.2 0.0 5.7 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM25966.1 - 8.2e-05 23.0 10.5 1.3 9.6 0.0 6.1 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM25966.1 - 0.00015 21.9 2.0 0.17 12.1 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM25966.1 - 0.0035 17.0 5.6 44 4.1 0.0 6.5 6 1 1 7 7 7 0 Ankyrin repeat Ank_3 PF13606.1 GAM25966.1 - 0.0082 16.2 6.4 0.89 9.9 0.0 6.0 7 0 0 7 7 7 1 Ankyrin repeat Peptidase_C97 PF05903.9 GAM25966.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 PPPDE putative peptidase domain TFIIS_C PF01096.13 GAM25967.1 - 0.0099 15.4 0.1 0.031 13.9 0.1 1.9 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Nop14 PF04147.7 GAM25967.1 - 0.015 13.3 2.1 0.017 13.0 1.4 1.2 1 0 0 1 1 1 0 Nop14-like family HIM1 PF08732.5 GAM25967.1 - 0.034 12.6 0.0 0.048 12.1 0.0 1.2 1 0 0 1 1 1 0 HIM1 Cwf_Cwc_15 PF04889.7 GAM25967.1 - 0.044 13.4 2.4 0.057 13.1 1.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 GAM25967.1 - 1.2 7.7 10.9 1.9 7.1 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TBD PF12845.2 GAM25968.1 - 1.9 8.0 4.3 15 5.2 0.3 2.3 2 0 0 2 2 2 0 TBD domain Dicty_CTDC PF00526.13 GAM25969.1 - 1.5e-15 56.5 102.1 5.1e-07 29.3 3.4 8.3 8 0 0 8 8 8 7 Dictyostelium (slime mold) repeat Filamin PF00630.14 GAM25969.1 - 1.1e-12 48.3 0.1 2.5e-10 40.8 0.0 3.2 3 1 0 3 3 3 1 Filamin/ABP280 repeat DDE_Tnp_4 PF13359.1 GAM25970.1 - 3.8e-08 33.0 0.0 6.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 GAM25970.1 - 0.0037 16.7 0.1 0.0072 15.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DUF2089 PF09862.4 GAM25970.1 - 0.014 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) DUF3619 PF12279.3 GAM25970.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Nop14 PF04147.7 GAM25970.1 - 0.29 9.0 22.0 0.033 12.1 12.3 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 GAM25970.1 - 0.31 9.0 6.5 0.41 8.6 4.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 GAM25970.1 - 1.5 8.4 12.7 3.4 7.2 8.8 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 GAM25970.1 - 2.6 6.4 17.1 3.6 5.9 11.9 1.2 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 GAM25970.1 - 2.8 7.0 13.8 4.5 6.3 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cpn60_TCP1 PF00118.19 GAM25971.1 - 6.4e-144 480.1 4.3 7.3e-144 479.9 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_ligase_aden PF01653.13 GAM25972.1 - 4e-73 246.1 0.1 6.6e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.11 GAM25972.1 - 3.4e-27 93.9 2.2 9.4e-27 92.5 1.5 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.2 GAM25972.1 - 1.9e-11 43.6 0.0 5.9e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 GAM25972.1 - 5.4e-10 39.2 0.2 1.1e-06 28.6 0.1 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain BRCT PF00533.21 GAM25972.1 - 2.4e-09 37.2 0.1 5e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DDHD PF02862.12 GAM25972.1 - 0.0017 18.2 0.5 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 DDHD domain PTCB-BRCT PF12738.2 GAM25972.1 - 0.0053 16.5 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF4602 PF15375.1 GAM25972.1 - 0.23 11.5 2.9 0.25 11.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Ret_tiss PF10044.4 GAM25973.1 - 1.4e-05 25.5 0.1 1.6e-05 25.3 0.1 1.3 1 1 0 1 1 1 1 Retinal tissue protein HTH_20 PF12840.2 GAM25973.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L2_C PF03947.13 GAM25974.1 - 2.8e-41 140.3 1.7 4.2e-41 139.7 1.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAM25974.1 - 1.7e-18 66.3 0.0 4.4e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cofilin_ADF PF00241.15 GAM25975.1 - 1.6e-30 105.5 0.8 1.7e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein BolA PF01722.13 GAM25976.1 - 1.6e-16 60.0 0.0 1.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Chitin_synth_2 PF03142.10 GAM25976.1 - 0.068 11.5 0.0 0.079 11.3 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase CLU PF13236.1 GAM25977.1 - 8.3e-49 165.9 0.0 1.7e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM25977.1 - 3.2e-08 33.7 0.1 7.2e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 GAM25977.1 - 0.078 12.9 3.4 0.64 9.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIA PF03153.8 GAM25977.1 - 3.6 7.3 12.6 6.1 6.6 8.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLU PF13236.1 GAM25978.1 - 1.1e-48 165.5 0.1 8.7e-48 162.6 0.0 2.3 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM25978.1 - 9.2e-09 35.4 0.6 8.1e-08 32.3 0.0 2.6 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 GAM25978.1 - 0.013 15.4 3.4 0.018 14.9 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM25978.1 - 0.033 14.0 1.9 0.16 11.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Coiled PF05710.7 GAM25979.1 - 0.015 15.7 4.2 0.017 15.5 2.9 1.1 1 0 0 1 1 1 0 Coiled coil Coiled PF05710.7 GAM25980.1 - 0.032 14.6 7.0 0.052 14.0 4.8 1.4 1 1 0 1 1 1 0 Coiled coil Pkinase PF00069.20 GAM25981.1 - 2.2e-68 230.2 0.0 2.9e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25981.1 - 4.9e-29 101.1 0.0 6.9e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 GAM25981.1 - 1.2e-05 25.7 0.1 5.3e-05 23.6 0.1 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 GAM25981.1 - 4.2e-05 22.6 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM25981.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM25981.1 - 0.099 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FYVE PF01363.16 GAM25982.1 - 5.9e-10 38.9 2.6 1.2e-09 37.9 1.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Pkinase PF00069.20 GAM25982.1 - 2.8e-05 23.4 0.1 9e-05 21.7 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM25982.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase WH2 PF02205.15 GAM25982.1 - 0.017 14.7 0.2 0.057 13.0 0.1 1.9 1 0 0 1 1 1 0 WH2 motif HIT PF01230.18 GAM25983.1 - 2.8e-26 91.9 0.0 3.4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 GAM25983.1 - 2.9e-08 33.9 0.0 3.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 GAM25983.1 - 0.053 13.1 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FNIP PF05725.7 GAM25984.1 - 2.5e-15 56.1 26.9 1.6e-07 31.1 0.1 7.9 3 2 5 9 9 9 7 FNIP Repeat Peptidase_C58 PF03543.9 GAM25984.1 - 0.055 12.9 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen FNIP PF05725.7 GAM25985.1 - 2.4e-76 251.4 27.7 1.6e-13 50.3 0.1 10.4 5 3 4 10 10 10 9 FNIP Repeat Ribosomal_L29 PF00831.18 GAM25987.1 - 0.24 11.1 1.5 0.45 10.2 0.2 2.0 2 0 0 2 2 2 0 Ribosomal L29 protein DUF3295 PF11702.3 GAM25988.1 - 0.12 11.3 2.2 0.17 10.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Ribosomal_L29 PF00831.18 GAM25988.1 - 0.45 10.2 2.6 0.45 10.2 0.2 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein Kelch_3 PF13415.1 GAM25989.1 - 1.5e-49 165.0 16.2 4.8e-11 42.5 0.0 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM25989.1 - 2.1e-44 149.0 14.2 5.5e-13 48.4 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM25989.1 - 1.4e-40 135.7 8.3 8.1e-11 41.6 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM25989.1 - 9.6e-39 130.6 9.7 6.4e-09 35.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM25989.1 - 1.6e-32 109.9 15.6 4.1e-07 29.5 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 GAM25989.1 - 6.9e-32 108.8 15.9 1.3e-06 28.2 0.3 6.6 7 0 0 7 7 7 6 Kelch motif SAM_2 PF07647.12 GAM25989.1 - 1.4e-10 40.8 0.1 2.5e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM25989.1 - 2.2e-09 37.3 0.1 4.2e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PQQ_3 PF13570.1 GAM25989.1 - 0.00094 19.3 0.3 6.9 7.0 0.0 4.1 5 0 0 5 5 5 2 PQQ-like domain RAG2 PF03089.9 GAM25989.1 - 0.017 13.8 2.2 2.5 6.7 0.0 4.2 3 2 2 5 5 5 0 Recombination activating protein 2 Suf PF05843.9 GAM25989.1 - 3.5 7.2 6.2 5 6.7 4.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_hydro_16 PF00722.16 GAM25990.1 - 2.8e-12 46.3 0.0 2.2e-11 43.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF566 PF04484.7 GAM25990.1 - 0.16 11.4 5.4 0.22 11.0 3.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) FMN_red PF03358.10 GAM25991.1 - 2.7e-23 82.1 0.0 3.7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM25991.1 - 3.6e-06 26.6 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold PFK PF00365.15 GAM25995.1 - 1.1e-176 585.6 3.6 1.2e-117 391.9 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase CBS PF00571.23 GAM25995.1 - 0.0025 17.5 0.2 0.18 11.6 0.0 3.6 4 0 0 4 4 4 1 CBS domain NYN PF01936.13 GAM25996.1 - 2.8e-22 79.5 0.2 2.8e-22 79.5 0.1 3.1 2 1 0 2 2 2 1 NYN domain OHA PF14418.1 GAM25996.1 - 1.8e-16 59.3 0.1 1.8e-16 59.3 0.0 2.5 2 0 0 2 2 2 1 OST-HTH Associated domain Med15 PF09606.5 GAM25996.1 - 0.00028 19.2 116.8 0.00043 18.6 81.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 GAM25996.1 - 0.39 8.9 93.7 0.75 7.9 65.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF544 PF04424.8 GAM25997.1 - 4.5e-24 84.5 1.6 9.6e-24 83.5 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF21 PF01595.15 GAM25998.1 - 2.1e-33 115.1 3.0 3.2e-33 114.5 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 GAM25998.1 - 9.5e-08 31.7 0.2 0.0013 18.4 0.1 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 GAM25998.1 - 0.01 15.6 0.0 0.032 14.0 0.0 1.9 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Dicty_REP PF05086.7 GAM25998.1 - 0.56 7.8 4.2 0.78 7.4 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cornichon PF03311.9 GAM25999.1 - 6.5e-31 107.1 9.5 8e-31 106.8 6.6 1.0 1 0 0 1 1 1 1 Cornichon protein p450 PF00067.17 GAM26000.1 - 8.1e-99 331.2 0.0 9.1e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM26001.1 - 6.1e-25 87.6 0.0 6.5e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 GAM26002.1 - 1.3e-54 185.0 0.0 2.2e-54 184.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26002.1 - 5.1e-53 179.7 0.0 7.7e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM26002.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM26002.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIP-T3 PF10243.4 GAM26003.1 - 0.0019 16.7 22.2 0.003 16.1 15.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 GAM26003.1 - 0.038 13.3 38.0 0.085 12.2 26.4 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 GAM26003.1 - 0.043 13.7 8.0 0.12 12.3 5.5 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family U79_P34 PF03064.11 GAM26003.1 - 4.3 6.7 16.7 11 5.4 11.6 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_11 PF13414.1 GAM26004.1 - 4.6e-06 26.1 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM26004.1 - 6.6e-06 25.5 0.1 0.0026 17.3 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26004.1 - 2e-05 24.8 1.1 0.21 12.3 0.0 4.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26004.1 - 7.3e-05 22.6 0.0 0.24 11.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26004.1 - 0.00016 22.2 0.0 0.26 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26004.1 - 0.00083 18.9 0.2 0.033 13.9 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26004.1 - 0.0017 18.2 0.1 0.55 10.2 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26004.1 - 0.002 18.4 0.2 0.01 16.2 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM26004.1 - 0.0026 17.5 0.1 0.26 11.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26004.1 - 0.011 16.0 0.1 2.7 8.4 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM26004.1 - 0.018 15.1 0.0 4.4 7.5 0.1 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 GAM26004.1 - 0.035 14.2 0.2 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM26004.1 - 0.05 13.4 0.0 0.86 9.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 GAM26004.1 - 0.062 12.0 0.1 0.79 8.4 0.1 2.3 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 GAM26004.1 - 0.076 12.9 0.1 19 5.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM26004.1 - 0.078 12.9 1.5 3 7.9 0.1 3.1 4 0 0 4 4 3 0 Tetratricopeptide repeat RXT2_N PF08595.6 GAM26006.1 - 0.1 12.4 1.2 0.26 11.0 0.8 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 GAM26006.1 - 6 7.1 11.0 17 5.7 7.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF1673 PF07895.6 GAM26007.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) CGGC PF08821.6 GAM26007.1 - 6.9 6.7 16.9 1.2 9.2 0.3 3.6 2 1 2 4 4 4 0 CGGC domain DEAD PF00270.24 GAM26008.1 - 4.9e-47 159.5 0.0 2.5e-46 157.2 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM26008.1 - 3.7e-24 84.3 0.4 3.4e-23 81.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM26008.1 - 1e-05 24.5 0.0 3.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain PAP2 PF01569.16 GAM26010.1 - 7.9e-18 64.3 0.9 7.9e-18 64.3 0.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily Transmemb_17 PF09799.4 GAM26010.1 - 0.0052 17.1 4.5 0.0052 17.1 3.2 1.8 2 0 0 2 2 2 1 Predicted membrane protein DUF3366 PF11846.3 GAM26010.1 - 0.11 12.3 3.7 0.16 11.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) SAF PF08666.7 GAM26010.1 - 0.13 12.6 0.0 9.7 6.6 0.0 2.9 2 1 1 3 3 3 0 SAF domain UbiA PF01040.13 GAM26010.1 - 0.32 10.1 10.5 0.73 8.9 6.9 1.9 1 1 0 1 1 1 0 UbiA prenyltransferase family Virul_fac_BrkB PF03631.10 GAM26010.1 - 0.62 9.3 11.3 2.9 7.1 7.9 1.8 1 1 0 1 1 1 0 Virulence factor BrkB DUF2368 PF10166.4 GAM26010.1 - 0.77 9.3 3.2 0.77 9.3 1.0 1.8 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Tic20 PF09685.5 GAM26010.1 - 1.3 9.0 7.1 0.69 9.9 1.5 2.2 2 0 0 2 2 2 0 Tic20-like protein Ank_2 PF12796.2 GAM26011.1 - 0.00012 22.3 0.0 0.13 12.6 0.0 3.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26011.1 - 0.0039 17.3 0.1 27 5.4 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 GAM26011.1 - 0.099 13.1 0.0 61 4.2 0.0 4.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF3550 PF12070.3 GAM26012.1 - 7.5e-155 516.5 5.2 7.5e-155 516.5 3.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3550/UPF0682) UPF0118 PF01594.11 GAM26012.1 - 0.3 10.0 1.3 0.56 9.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF20 CPSF100_C PF13299.1 GAM26012.1 - 5.6 7.1 12.3 0.28 11.3 0.3 2.7 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF4041 PF13250.1 GAM26013.1 - 0.012 15.1 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) dNK PF01712.14 GAM26014.1 - 4.3e-29 101.2 3.8 6.5e-29 100.7 2.7 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 GAM26014.1 - 4.3e-05 22.9 0.2 6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Thymidylate kinase Herpes_TK PF00693.13 GAM26014.1 - 0.0027 16.9 0.0 0.0034 16.5 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase from herpesvirus AAA_18 PF13238.1 GAM26014.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.10 GAM26015.1 - 3.8e-10 38.9 7.0 3.8e-10 38.9 4.8 1.6 2 1 0 2 2 2 1 Tim10/DDP family zinc finger APG6 PF04111.7 GAM26015.1 - 0.00072 18.6 0.4 0.0009 18.3 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 FYVE_2 PF02318.11 GAM26015.1 - 0.63 9.9 7.3 1.4 8.8 5.0 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger Pex2_Pex12 PF04757.9 GAM26016.1 - 6e-45 153.4 4.7 8e-45 153.0 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 GAM26016.1 - 1.3e-06 28.0 11.4 1.9e-06 27.4 7.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 GAM26016.1 - 5.9e-06 26.2 14.0 1e-05 25.4 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM26016.1 - 7.1e-06 25.5 12.6 1.2e-05 24.8 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM26016.1 - 3.9e-05 23.2 9.1 5.7e-05 22.7 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM26016.1 - 0.0001 22.0 11.6 0.00016 21.4 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAM26016.1 - 0.0081 16.0 15.5 0.014 15.2 10.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM26016.1 - 0.041 13.6 7.0 0.095 12.4 4.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Dicty_CTDC PF00526.13 GAM26017.1 - 6.6e-88 287.6 376.7 7.9e-09 35.1 7.8 29.2 29 1 0 29 29 29 23 Dictyostelium (slime mold) repeat zf-TAZ PF02135.11 GAM26017.1 - 1.7e-15 56.8 118.8 0.016 15.2 0.0 13.9 1 1 14 15 15 15 11 TAZ zinc finger Dicty_CTDC PF00526.13 GAM26020.1 - 2.1e-97 317.9 529.4 1.5e-06 27.8 6.8 41.6 40 2 1 41 41 41 32 Dictyostelium (slime mold) repeat zf-TAZ PF02135.11 GAM26020.1 - 6.1e-08 32.5 197.8 0.0062 16.5 0.5 20.0 1 1 23 24 24 24 17 TAZ zinc finger Metallothio_Pro PF02069.11 GAM26021.1 - 1.5 8.7 5.3 0.66 9.8 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic metallothionein RXT2_N PF08595.6 GAM26022.1 - 0.003 17.3 2.8 0.018 14.8 1.7 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal DUF2457 PF10446.4 GAM26022.1 - 0.022 13.5 13.6 0.035 12.8 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 GAM26022.1 - 0.022 14.6 10.9 0.092 12.6 8.2 1.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 GAM26022.1 - 0.055 13.3 4.2 0.085 12.7 2.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ebola_NP PF05505.7 GAM26022.1 - 0.07 11.1 3.2 0.095 10.7 2.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Nop14 PF04147.7 GAM26022.1 - 0.23 9.3 11.1 0.32 8.8 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 GAM26022.1 - 0.48 8.6 1.6 0.6 8.3 1.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sporozoite_P67 PF05642.6 GAM26022.1 - 0.53 8.0 3.5 0.67 7.7 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 GAM26022.1 - 0.65 7.9 6.4 0.94 7.4 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Mak16 PF04874.9 GAM26022.1 - 1 9.5 13.6 1.9 8.5 9.4 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region TRAP_alpha PF03896.11 GAM26022.1 - 4.9 6.0 7.5 7.8 5.4 5.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CBM49 PF09478.5 GAM26023.1 - 8.6e-14 51.3 0.9 8.6e-14 51.3 0.6 2.3 3 0 0 3 3 3 1 Carbohydrate binding domain CBM49 Methyltransf_16 PF10294.4 GAM26024.1 - 1.5e-23 83.1 0.0 2.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 GAM26024.1 - 0.0018 17.4 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 GAM26024.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM26024.1 - 0.024 14.2 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 GAM26024.1 - 0.025 15.1 0.0 0.074 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAM26024.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CLU PF13236.1 GAM26025.1 - 8e-44 149.6 0.0 1.5e-43 148.8 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria Ras PF00071.17 GAM26025.1 - 1e-37 129.0 0.2 2e-37 128.0 0.1 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM26025.1 - 9e-17 61.6 0.0 2.8e-16 60.0 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM26025.1 - 1.4e-09 37.4 0.3 2.3e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family eIF3_p135 PF12807.2 GAM26025.1 - 2.4e-06 27.5 0.0 2.4e-06 27.5 0.0 2.4 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_19 PF14559.1 GAM26025.1 - 0.0097 16.2 0.0 0.032 14.5 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Ribosomal_60s PF00428.14 GAM26025.1 - 0.18 12.2 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_14 PF13428.1 GAM26025.1 - 0.3 11.8 0.0 1.4 9.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26025.1 - 0.81 9.7 4.0 1.6 8.8 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26025.1 - 3.1 8.2 0.0 3.1 8.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 GAM26026.1 - 6.4e-65 218.7 0.0 8.7e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26026.1 - 1.9e-59 200.9 0.0 2.7e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 GAM26026.1 - 0.0043 16.8 2.4 0.029 14.1 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 GAM26026.1 - 0.027 13.8 0.2 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Slu7 PF11708.3 GAM26027.1 - 2.2e-69 233.8 10.2 2.2e-69 233.8 7.1 3.3 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 GAM26027.1 - 0.015 14.9 2.4 0.039 13.6 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4148 PF13663.1 GAM26027.1 - 0.15 11.9 1.2 0.33 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DHQ_synthase PF01761.15 GAM26027.1 - 0.16 10.8 5.0 0.44 9.4 3.4 1.7 1 0 0 1 1 1 0 3-dehydroquinate synthase RNA_pol_Rpb5_C PF01191.14 GAM26027.1 - 0.42 10.2 3.9 3.5 7.2 0.2 3.2 2 1 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Zip PF02535.17 GAM26027.1 - 1.9 7.4 5.1 2.9 6.8 3.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Rpn3_C PF08375.6 GAM26028.1 - 2.6e-19 69.3 0.1 6.9e-19 68.0 0.1 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 GAM26028.1 - 5.6e-18 65.2 0.0 5.6e-18 65.2 0.0 2.9 3 2 0 3 3 3 1 PCI domain TPR_2 PF07719.12 GAM26028.1 - 0.009 15.8 1.1 0.21 11.5 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26028.1 - 0.17 11.8 6.6 2 8.4 0.6 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1548 PF07579.6 GAM26028.1 - 0.31 11.1 3.7 4.9 7.2 0.1 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1548) TPR_1 PF00515.23 GAM26028.1 - 0.41 10.3 2.3 7.4 6.3 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2305 PF10230.4 GAM26030.1 - 2e-52 178.2 0.0 2.4e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 GAM26030.1 - 1.4e-06 28.3 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM26030.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 GAM26030.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3089 PF11288.3 GAM26030.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PWI PF01480.12 GAM26032.1 - 0.017 15.1 0.4 0.017 15.1 0.3 1.9 2 0 0 2 2 2 0 PWI domain DUF1406 PF07190.6 GAM26032.1 - 0.76 9.4 6.0 0.13 11.9 0.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1406) COesterase PF00135.23 GAM26032.1 - 8.2 5.0 9.6 12 4.4 6.6 1.4 1 1 0 1 1 1 0 Carboxylesterase family RhoGAP PF00620.22 GAM26033.1 - 2.6e-12 46.6 0.0 6.4e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain MACPF PF01823.14 GAM26034.1 - 3.4e-19 69.3 3.2 3.4e-19 69.3 2.2 2.2 1 1 1 2 2 2 2 MAC/Perforin domain MACPF PF01823.14 GAM26035.1 - 1.3e-18 67.4 3.2 1.3e-18 67.4 2.2 1.9 2 0 0 2 2 2 1 MAC/Perforin domain TraG-D_C PF12696.2 GAM26037.1 - 0.25 11.1 1.2 0.27 11.1 0.8 1.1 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DNase_II PF03265.10 GAM26038.1 - 1.7e-05 23.9 0.1 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Deoxyribonuclease II Mucin PF01456.12 GAM26038.1 - 0.0047 16.7 15.1 0.0088 15.8 10.5 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 GAM26038.1 - 0.013 15.2 10.6 0.025 14.3 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sporozoite_P67 PF05642.6 GAM26038.1 - 0.051 11.4 7.3 0.078 10.8 5.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 GAM26038.1 - 0.37 8.7 13.0 0.47 8.3 9.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FNIP PF05725.7 GAM26040.1 - 3.7e-90 295.6 28.0 1.6e-14 53.5 0.7 9.7 2 2 6 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 GAM26040.1 - 0.0083 16.0 10.8 9.4 6.2 0.0 7.3 4 3 4 8 8 8 1 Protein of unknown function (DUF1769) ATE_C PF04377.10 GAM26040.1 - 0.047 13.7 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Aldedh PF00171.17 GAM26041.1 - 8.4e-125 416.7 0.0 1e-124 416.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GATA PF00320.22 GAM26044.1 - 1.4e-07 30.6 4.8 3.5e-07 29.4 3.3 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.26 GAM26044.1 - 0.00012 22.0 0.1 0.00027 20.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM26044.1 - 0.00049 20.1 2.8 0.0014 18.6 1.9 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nudix_N_2 PF14803.1 GAM26044.1 - 0.96 9.1 3.1 2.3 7.9 2.1 1.6 1 0 0 1 1 1 0 Nudix N-terminal Yippee-Mis18 PF03226.9 GAM26044.1 - 1.9 8.5 5.1 2.7 8.1 1.1 3.2 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PX PF00787.19 GAM26045.1 - 1.2e-19 70.1 3.3 1.5e-19 69.8 2.3 1.1 1 0 0 1 1 1 1 PX domain PQ-loop PF04193.9 GAM26046.1 - 2.5e-13 49.3 20.3 1.6e-06 27.5 4.7 2.9 2 0 0 2 2 2 2 PQ loop repeat Acyl_transf_3 PF01757.17 GAM26046.1 - 0.00033 19.6 11.9 0.00033 19.6 8.2 2.2 2 0 0 2 2 2 2 Acyltransferase family HATPase_c PF02518.21 GAM26047.1 - 1.7e-22 79.2 0.0 3.7e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM26047.1 - 3.7e-19 68.4 0.0 1.1e-18 67.0 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 GAM26047.1 - 1e-18 67.3 0.0 2.8e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 GAM26047.1 - 5.7e-05 23.4 0.1 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 GAM26047.1 - 0.0053 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.1 GAM26047.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 GAF domain Cytokin_check_N PF10407.4 GAM26047.1 - 0.035 13.7 0.5 0.096 12.3 0.3 1.8 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus GAF_2 PF13185.1 GAM26047.1 - 0.04 14.3 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 GAF domain DUF1510 PF07423.6 GAM26048.1 - 0.36 10.1 18.3 0.7 9.2 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LMBR1 PF04791.11 GAM26048.1 - 0.6 8.6 4.1 0.75 8.3 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SprA-related PF12118.3 GAM26048.1 - 1.3 8.2 27.6 1.7 7.8 19.1 1.1 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 GAM26048.1 - 2.5 8.1 11.3 0.17 11.9 3.7 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S28 PF05577.7 GAM26049.1 - 3.1e-74 250.1 3.6 1.8e-42 145.4 0.1 2.2 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAM26049.1 - 3.8e-07 30.2 0.2 1.2e-06 28.5 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM26049.1 - 9.9e-06 25.2 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM26049.1 - 7.7e-05 22.4 0.2 0.0002 21.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM26049.1 - 0.00012 21.3 0.4 0.00032 19.9 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.6 GAM26049.1 - 0.011 14.2 0.0 0.019 13.4 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 DUF2920 PF11144.3 GAM26049.1 - 0.23 10.4 0.2 0.46 9.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Flagellin_C PF00700.16 GAM26049.1 - 0.24 11.5 1.3 0.36 11.0 0.1 1.9 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Oxysterol_BP PF01237.13 GAM26050.1 - 1.1e-62 211.5 1.2 1.5e-62 211.1 0.8 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Adeno_knob PF00541.12 GAM26050.1 - 0.0059 16.2 0.1 0.011 15.4 0.1 1.6 1 0 0 1 1 1 1 Adenoviral fibre protein (knob domain) DUF4411 PF14367.1 GAM26050.1 - 0.22 11.2 3.5 0.14 11.8 0.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4411) Peptidase_M41 PF01434.13 GAM26051.1 - 2.8e-72 242.6 0.3 3.9e-72 242.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAM26051.1 - 1.6e-42 144.8 0.0 4.4e-42 143.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM26051.1 - 3.2e-05 23.6 0.0 0.00016 21.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM26051.1 - 0.00032 20.8 0.3 0.045 13.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM26051.1 - 0.0007 19.9 0.5 0.99 9.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain FtsH_ext PF06480.10 GAM26051.1 - 0.0016 18.6 0.0 0.0016 18.6 0.0 2.5 3 1 0 3 3 3 1 FtsH Extracellular AAA_17 PF13207.1 GAM26051.1 - 0.002 18.9 0.1 0.01 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 GAM26051.1 - 0.0068 15.1 0.1 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 GAM26051.1 - 0.0087 15.9 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM26051.1 - 0.0094 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM26051.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 GAM26051.1 - 0.012 14.6 0.0 0.039 12.9 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM26051.1 - 0.014 15.3 0.2 0.13 12.2 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 GAM26051.1 - 0.024 14.0 2.0 0.043 13.2 0.4 2.1 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.12 GAM26051.1 - 0.025 13.9 0.5 0.061 12.7 0.4 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 GAM26051.1 - 0.029 14.2 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 GAM26051.1 - 0.051 12.7 0.3 0.15 11.1 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 GAM26051.1 - 0.063 13.0 3.0 0.058 13.1 0.8 1.9 2 0 0 2 2 1 0 Part of AAA domain DUF2108 PF09881.4 GAM26051.1 - 0.088 12.6 0.2 0.28 11.0 0.1 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) AAA_28 PF13521.1 GAM26051.1 - 0.15 12.0 0.2 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rav1p_C PF12234.3 GAM26052.1 - 5.3e-75 252.8 0.1 5.3e-75 252.8 0.0 1.9 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 GAM26052.1 - 1.3e-15 56.6 33.5 0.0024 17.6 0.1 11.1 13 0 0 13 13 13 8 WD domain, G-beta repeat PQQ_3 PF13570.1 GAM26052.1 - 0.054 13.7 0.0 4.8 7.5 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Glycos_transf_1 PF00534.15 GAM26053.1 - 4.8e-28 97.7 0.0 7.7e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.21 GAM26053.1 - 5.2e-25 88.0 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM26053.1 - 4.1e-16 59.4 0.0 1.9e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_1_4 PF13692.1 GAM26053.1 - 2.8e-11 43.7 0.0 7.5e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.4 GAM26053.1 - 1e-07 31.3 0.0 2.9e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM26053.1 - 3.7e-06 26.7 0.2 8.4e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.1 GAM26053.1 - 0.00015 21.9 0.0 0.00039 20.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM26053.1 - 0.0013 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_7C PF02709.9 GAM26053.1 - 0.012 15.0 0.7 0.04 13.3 0.5 1.8 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Peroxin-3 PF04882.7 GAM26053.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Peroxin-3 Cytokin_check_N PF10407.4 GAM26055.1 - 0.0077 15.8 0.0 0.036 13.6 0.0 2.1 1 1 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SAGA-Tad1 PF12767.2 GAM26055.1 - 0.46 10.1 11.8 0.02 14.5 3.9 1.8 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit RNA_pol_Rpc34 PF05158.7 GAM26056.1 - 3.2e-69 233.6 5.9 5e-46 157.3 2.6 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.14 GAM26056.1 - 2e-05 24.2 0.5 0.008 15.8 0.1 3.1 3 0 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.6 GAM26056.1 - 4e-05 23.9 2.7 0.098 13.0 0.1 3.2 1 1 2 3 3 3 2 Replication protein A C terminal B-block_TFIIIC PF04182.7 GAM26056.1 - 0.00013 21.7 0.9 0.00072 19.3 0.1 2.4 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC TAFII28 PF04719.9 GAM26056.1 - 0.021 14.6 0.2 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region MarR_2 PF12802.2 GAM26056.1 - 0.025 14.2 0.2 6.6 6.4 0.0 3.1 3 0 0 3 3 3 0 MarR family RibD_C PF01872.12 GAM26056.1 - 0.048 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain Rubis-subs-bind PF09273.6 GAM26057.1 - 1e-20 73.9 2.0 2e-20 73.0 1.4 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 GAM26057.1 - 7.9e-13 49.0 0.0 2.9e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 SET domain OsmC PF02566.14 GAM26059.1 - 1.8e-17 63.3 0.3 2.2e-17 63.0 0.2 1.1 1 0 0 1 1 1 1 OsmC-like protein Prefoldin_2 PF01920.15 GAM26060.1 - 5e-12 45.5 9.3 6.6e-12 45.1 6.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 GAM26060.1 - 0.011 15.3 9.7 0.015 14.9 1.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit V-ATPase_C PF03223.10 GAM26060.1 - 0.16 10.8 3.3 0.18 10.7 2.3 1.1 1 0 0 1 1 1 0 V-ATPase subunit C LRS4 PF10422.4 GAM26060.1 - 0.18 11.1 3.0 0.23 10.8 2.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 CDC37_N PF03234.9 GAM26060.1 - 0.35 11.1 9.4 0.43 10.8 6.5 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Fib_alpha PF08702.5 GAM26060.1 - 0.51 10.4 7.0 3.4 7.7 0.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 GAM26060.1 - 0.52 10.2 3.2 1 9.3 1.5 2.0 1 1 1 2 2 2 0 FlxA-like protein Rho_Binding PF08912.6 GAM26060.1 - 3.2 8.1 9.8 14 6.0 1.7 3.0 2 1 1 3 3 3 0 Rho Binding DUF948 PF06103.6 GAM26060.1 - 6.7 6.6 5.8 5.4 6.9 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.10 GAM26061.1 - 2.3e-26 92.3 6.4 2.3e-26 92.3 4.4 3.0 3 0 0 3 3 3 1 Sec34-like family PP2C_C PF07830.8 GAM26061.1 - 0.03 14.4 0.1 0.15 12.1 0.0 2.2 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain RasGAP PF00616.14 GAM26062.1 - 1.6e-30 106.2 0.0 1.6e-30 106.2 0.0 4.0 3 2 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 GAM26062.1 - 6.7e-30 103.3 8.7 6.2e-17 61.5 0.0 4.5 4 0 0 4 4 4 2 Calponin homology (CH) domain DUF3899 PF13038.1 GAM26062.1 - 5.5 7.2 0.0 5.5 7.2 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF3899) CENP-B_dimeris PF09026.5 GAM26063.1 - 0.0033 17.6 14.9 0.0033 17.6 10.3 2.5 2 0 0 2 2 2 1 Centromere protein B dimerisation domain CENP-T PF15511.1 GAM26063.1 - 0.13 11.4 4.6 1.2 8.3 2.2 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Cwf_Cwc_15 PF04889.7 GAM26063.1 - 1.5 8.4 23.7 2.6 7.6 9.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Prothymosin PF03247.9 GAM26063.1 - 3.4 7.8 31.5 0.5 10.5 11.5 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family RNA_pol_3_Rpc31 PF11705.3 GAM26063.1 - 7.4 6.4 30.8 2 8.2 15.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 GAM26063.1 - 9.4 4.0 19.5 0.024 12.6 6.3 1.7 2 0 0 2 2 2 0 Nop14-like family Ank_2 PF12796.2 GAM26064.1 - 4.9e-12 46.0 3.5 0.06 13.6 0.0 7.0 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26064.1 - 0.0065 16.9 6.0 7.8 7.1 0.1 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26065.1 - 3.1e-09 37.0 0.3 9.9e-05 22.6 0.5 4.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26065.1 - 2.4e-07 30.3 1.4 0.82 10.0 0.1 6.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 GAM26065.1 - 0.0022 18.4 2.2 22 5.7 0.1 5.0 3 3 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM26065.1 - 0.0037 16.9 0.1 1.4 8.8 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 GAM26065.1 - 0.084 13.1 0.0 43 4.5 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26066.1 - 1.3e-19 70.3 1.9 5.6e-05 23.4 0.6 8.5 6 4 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26066.1 - 2.3e-06 27.2 18.9 3.5 8.1 0.1 11.2 13 0 0 13 13 13 1 Ankyrin repeat Ank PF00023.25 GAM26066.1 - 2.2e-05 24.0 10.4 0.96 9.3 0.0 8.1 9 0 0 9 9 9 1 Ankyrin repeat Ank_4 PF13637.1 GAM26066.1 - 7.7e-05 23.0 9.9 21 5.7 0.1 8.2 7 2 3 10 10 10 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26066.1 - 0.079 13.2 6.0 99 3.3 0.0 7.6 8 0 0 8 8 8 0 Ankyrin repeats (many copies) Cyto_heme_lyase PF01265.12 GAM26067.1 - 1.2e-76 257.6 0.5 1.5e-76 257.4 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF2963 PF11178.3 GAM26067.1 - 0.099 12.0 1.9 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) tRNA_bind PF01588.15 GAM26068.1 - 1.2e-19 69.9 0.1 2.2e-13 49.8 0.0 2.2 1 1 0 2 2 2 2 Putative tRNA binding domain Pex14_N PF04695.8 GAM26068.1 - 0.048 13.7 0.9 0.074 13.1 0.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3157 PF11355.3 GAM26068.1 - 0.074 12.3 0.9 0.098 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) DUF2267 PF10025.4 GAM26068.1 - 0.08 13.0 0.1 0.15 12.1 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) RE_Alw26IDE PF09665.5 GAM26068.1 - 0.15 10.7 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Nuc_sug_transp PF04142.10 GAM26069.1 - 2.4e-11 43.1 5.5 4.4e-11 42.3 3.8 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 GAM26069.1 - 1.1e-05 25.1 22.6 0.00023 20.8 9.8 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 GAM26069.1 - 1.2e-05 25.3 2.2 1.2e-05 25.3 1.5 3.6 2 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 GAM26069.1 - 0.00069 19.7 2.4 0.00069 19.7 1.7 3.8 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF3446 PF11928.3 GAM26069.1 - 0.051 13.7 9.8 0.15 12.2 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF1634 PF07843.6 GAM26069.1 - 0.39 10.3 8.1 0.98 9.0 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1634) DUF4149 PF13664.1 GAM26069.1 - 5.1 7.2 15.6 0.7 9.9 2.9 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4149) AAA PF00004.24 GAM26070.1 - 3.7e-07 30.4 0.2 1.2e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 GAM26070.1 - 4.9e-06 25.5 0.6 1.4e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAM26070.1 - 6.6e-05 23.0 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 GAM26070.1 - 0.00062 20.2 0.0 0.0036 17.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 GAM26070.1 - 0.0012 19.1 0.1 0.0092 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM26070.1 - 0.0013 18.6 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM26070.1 - 0.012 15.8 0.0 0.053 13.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 GAM26070.1 - 0.015 14.4 0.2 0.042 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM26070.1 - 0.016 16.0 0.0 0.053 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM26070.1 - 0.018 14.7 0.0 0.064 12.9 0.0 1.9 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 GAM26070.1 - 0.053 13.3 0.2 0.17 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 GAM26070.1 - 0.069 13.1 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 GAM26070.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 GAM26070.1 - 0.14 12.4 13.5 1.1 9.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain eRF1_2 PF03464.10 GAM26071.1 - 0.032 14.5 0.1 0.089 13.1 0.0 1.7 1 0 0 1 1 1 0 eRF1 domain 2 PIG-P PF08510.7 GAM26072.1 - 4e-34 116.9 5.3 4e-34 116.9 3.7 2.4 2 0 0 2 2 2 1 PIG-P OATP PF03137.15 GAM26072.1 - 0.0055 14.8 0.3 0.0055 14.8 0.2 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF1279 PF06916.8 GAM26072.1 - 0.057 13.7 1.2 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) NMO PF03060.10 GAM26072.1 - 0.093 11.8 0.5 0.17 10.9 0.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Vma12 PF11712.3 GAM26072.1 - 0.13 11.9 3.8 0.042 13.5 0.4 1.8 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4448 PF14610.1 GAM26072.1 - 0.14 11.6 4.7 6.8 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) FHIPEP PF00771.15 GAM26072.1 - 0.18 10.1 1.6 0.25 9.6 1.1 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4407 PF14362.1 GAM26072.1 - 0.68 8.8 7.4 0.19 10.6 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Suf PF05843.9 GAM26072.1 - 0.7 9.5 11.5 0.04 13.6 3.5 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 GAM26072.1 - 1 9.1 14.2 0.19 11.5 7.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) FimP PF09766.4 GAM26072.1 - 1 8.3 15.1 0.35 9.8 7.5 1.9 2 0 0 2 2 2 0 Fms-interacting protein Zip PF02535.17 GAM26072.1 - 1.4 7.9 7.6 0.14 11.1 0.8 2.1 2 1 0 2 2 2 0 ZIP Zinc transporter PAT1 PF09770.4 GAM26072.1 - 1.8 6.6 25.4 3 5.9 17.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AIF_C PF14721.1 GAM26072.1 - 2.2 8.5 6.6 1 9.6 0.9 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SprA-related PF12118.3 GAM26072.1 - 5.1 6.3 34.3 0.031 13.5 12.7 2.2 2 0 0 2 2 2 0 SprA-related family ATP-synt_E PF05680.7 GAM26072.1 - 5.2 7.0 8.5 2.4 8.1 4.0 1.8 2 0 0 2 2 2 0 ATP synthase E chain DPM2 PF07297.7 GAM26072.1 - 6.7 7.0 8.8 12 6.2 6.1 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF1084 PF06454.6 GAM26073.1 - 6.6e-20 71.2 19.6 1.1e-19 70.5 13.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF3007 PF11460.3 GAM26073.1 - 0.14 12.2 6.1 2.8 8.0 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) Ferric_reduct PF01794.14 GAM26073.1 - 0.4 10.7 9.8 0.86 9.7 0.2 2.8 2 1 0 3 3 3 0 Ferric reductase like transmembrane component DUF1774 PF08611.5 GAM26073.1 - 3.9 7.7 13.7 0.037 14.1 1.3 3.2 3 1 0 3 3 3 0 Fungal protein of unknown function (DUF1774) Beach PF02138.13 GAM26074.1 - 1.1e-108 362.8 0.7 1.1e-108 362.8 0.5 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 GAM26074.1 - 3.1e-18 65.5 0.0 7.4e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 GAM26074.1 - 1.4e-16 59.6 10.7 7.1e-06 25.7 1.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat SNARE PF05739.14 GAM26075.1 - 3e-10 39.6 2.6 3e-10 39.6 1.8 1.8 2 0 0 2 2 2 1 SNARE domain PGA2 PF07543.7 GAM26075.1 - 0.031 14.0 1.4 0.054 13.2 1.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 TraG_N PF07916.6 GAM26075.1 - 2.8 6.2 9.9 4.6 5.5 6.8 1.5 1 1 0 1 1 1 0 TraG-like protein, N-terminal region FNIP PF05725.7 GAM26076.1 - 2.1e-104 341.2 9.6 9.8e-12 44.6 0.0 11.3 4 3 10 15 15 15 14 FNIP Repeat LRR_5 PF13306.1 GAM26076.1 - 0.0034 17.0 0.0 3.4 7.3 0.0 2.8 2 1 0 2 2 2 2 Leucine rich repeats (6 copies) MOZART1 PF12554.3 GAM26076.1 - 0.16 11.4 0.1 18 4.8 0.0 3.0 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated Arm PF00514.18 GAM26076.1 - 0.16 11.8 0.1 52 3.8 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TPR_12 PF13424.1 GAM26077.1 - 8.2e-77 253.1 25.3 1.9e-16 59.7 0.0 8.2 4 3 2 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 GAM26077.1 - 5.3e-44 146.9 0.0 0.0002 21.1 0.0 11.8 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.23 GAM26077.1 - 6.3e-38 126.8 44.9 0.00067 19.1 0.0 11.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 GAM26077.1 - 1.2e-36 124.2 29.9 7.5e-09 35.1 0.1 8.6 4 2 4 9 9 9 8 TPR repeat TPR_2 PF07719.12 GAM26077.1 - 2.4e-32 108.2 35.7 0.0038 17.0 0.7 11.9 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26077.1 - 1.2e-23 81.0 46.6 0.0011 18.5 0.0 10.9 10 1 1 11 11 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 GAM26077.1 - 1.7e-22 77.3 15.1 0.0011 18.6 0.0 9.6 9 1 1 10 10 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26077.1 - 4e-18 65.5 5.1 0.031 14.9 0.0 8.5 5 1 4 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26077.1 - 7.8e-15 54.9 11.4 0.0037 17.5 0.0 7.5 5 3 2 7 7 7 3 Tetratricopeptide repeat BRCT PF00533.21 GAM26077.1 - 1e-08 35.2 0.1 3.5e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4062 PF13271.1 GAM26077.1 - 2.7e-08 33.6 0.0 2.1e-07 30.8 0.0 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) NACHT PF05729.7 GAM26077.1 - 3e-06 26.9 0.0 1e-05 25.2 0.0 2.0 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 GAM26077.1 - 3e-06 27.3 7.3 23 5.9 0.0 9.6 8 3 4 12 12 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26077.1 - 1.1e-05 25.1 9.5 11 6.5 0.0 8.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26077.1 - 0.00018 21.7 20.3 19 6.0 0.7 9.8 9 1 0 9 9 8 0 Tetratricopeptide repeat DUF4404 PF14357.1 GAM26077.1 - 0.017 15.5 0.0 7.9 6.9 0.0 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4404) UBA PF00627.26 GAM26077.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 UBA/TS-N domain MIT PF04212.13 GAM26077.1 - 0.24 11.2 23.5 0.74 9.7 0.8 7.3 7 1 1 8 8 7 0 MIT (microtubule interacting and transport) domain 14-3-3 PF00244.15 GAM26077.1 - 1.2 8.2 15.0 2 7.4 0.2 5.5 3 1 2 5 5 5 0 14-3-3 protein LRR_8 PF13855.1 GAM26078.1 - 3.3e-08 33.1 10.3 0.011 15.5 0.2 6.6 4 2 1 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 GAM26078.1 - 8.6e-07 28.4 23.3 0.32 11.1 0.0 9.9 10 0 0 10 10 10 1 Leucine Rich repeat LRR_4 PF12799.2 GAM26078.1 - 2.8e-06 26.8 9.6 4.2 7.1 0.2 7.3 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM26078.1 - 0.00091 18.9 18.2 0.75 10.0 0.0 8.3 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_7 PF13504.1 GAM26078.1 - 0.0044 16.9 12.8 39 5.0 0.0 8.0 8 0 0 8 8 8 0 Leucine rich repeat Herpes_alk_exo PF01771.12 GAM26078.1 - 0.043 12.2 0.1 0.071 11.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus alkaline exonuclease DUF4217 PF13959.1 GAM26078.1 - 0.12 11.9 0.4 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) Cast PF10174.4 GAM26078.1 - 0.36 8.8 0.6 0.51 8.3 0.4 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Sugarporin_N PF11471.3 GAM26079.1 - 0.00077 19.0 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF501 PF04417.7 GAM26080.1 - 0.85 9.4 4.7 16 5.3 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF501) DUF4606 PF15379.1 GAM26080.1 - 2.5 8.2 5.3 0.83 9.7 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) Vac_ImportDeg PF09783.4 GAM26082.1 - 2.9e-45 153.9 5.7 3.5e-45 153.6 3.9 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF1336 PF07059.7 GAM26082.1 - 0.011 15.2 0.2 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) FNIP PF05725.7 GAM26083.1 - 9.1e-79 259.2 36.0 1.5e-13 50.4 0.2 9.3 3 3 7 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 GAM26083.1 - 4e-06 26.6 6.1 2.7 7.9 0.0 6.4 4 2 4 8 8 8 3 Protein of unknown function (DUF1769) tRNA-synt_2b PF00587.20 GAM26084.1 - 8.5e-35 119.8 0.0 1.5e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM26084.1 - 0.035 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain RhoGEF PF00621.15 GAM26085.1 - 3.3e-48 163.9 1.9 3.3e-48 163.9 1.3 1.9 2 0 0 2 2 2 1 RhoGEF domain CAF-1_p150 PF11600.3 GAM26085.1 - 0.00017 21.0 64.8 0.00017 21.0 44.9 4.0 5 1 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 GAM26085.1 - 3.7 7.3 41.9 0.48 10.2 24.7 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Pkinase_Tyr PF07714.12 GAM26086.1 - 9.5e-66 221.5 0.0 1.4e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26086.1 - 1.9e-49 168.1 0.0 4.1e-49 167.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain SPRY PF00622.23 GAM26086.1 - 4.7e-46 155.8 9.0 2.2e-16 60.0 0.0 3.5 3 0 0 3 3 3 3 SPRY domain SAM_2 PF07647.12 GAM26086.1 - 7.4e-12 44.9 0.0 1.8e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM26086.1 - 8.8e-10 38.6 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Paralemmin PF03285.10 GAM26087.1 - 0.49 9.8 3.7 0.65 9.4 0.1 2.4 1 1 0 2 2 2 0 Paralemmin Myb_DNA-binding PF00249.26 GAM26088.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM26088.1 - 0.064 13.3 0.2 0.064 13.3 0.2 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA_33 PF13671.1 GAM26089.1 - 1.6e-21 76.7 0.0 1.1e-20 73.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM26089.1 - 6.7e-06 26.9 0.0 2.3e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM26089.1 - 0.0097 16.2 1.8 2 8.7 0.0 3.7 3 2 1 4 4 4 2 AAA domain Pex14_N PF04695.8 GAM26089.1 - 0.26 11.3 12.6 0.98 9.4 4.6 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_25 PF01183.15 GAM26090.1 - 2.7e-13 50.1 0.1 3.1e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 E1-E2_ATPase PF00122.15 GAM26091.1 - 1.9e-34 118.6 0.0 1.9e-34 118.6 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 GAM26091.1 - 7.4e-25 88.2 0.0 1.8e-24 86.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM26091.1 - 3.6e-20 73.3 0.0 1.2e-19 71.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 GAM26091.1 - 1.4e-19 70.0 0.9 3.7e-19 68.7 0.6 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 GAM26091.1 - 0.0038 17.1 0.0 0.0084 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM26091.1 - 0.073 12.6 0.0 9 5.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_C97 PF05903.9 GAM26092.1 - 9.8e-42 142.2 0.1 2.1e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 GAM26092.1 - 4.9e-23 81.2 1.2 8.4e-23 80.5 0.8 1.3 1 0 0 1 1 1 1 PUL domain LRAT PF04970.8 GAM26092.1 - 0.05 13.5 0.2 0.05 13.5 0.2 2.5 3 0 0 3 3 3 0 Lecithin retinol acyltransferase zf-C3Hc3H PF13891.1 GAM26092.1 - 0.059 13.4 0.7 0.27 11.3 0.2 2.2 2 0 0 2 2 2 0 Potential DNA-binding domain FliS PF02561.9 GAM26092.1 - 0.09 12.6 0.6 0.73 9.6 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliS Ovate PF04844.8 GAM26092.1 - 0.096 12.4 1.2 1.7 8.4 0.3 2.6 2 0 0 2 2 2 0 Transcriptional repressor, ovate FNIP PF05725.7 GAM26093.1 - 4.3e-101 330.6 47.3 1e-14 54.2 0.2 10.0 3 2 8 13 13 13 12 FNIP Repeat MerC PF03203.9 GAM26093.1 - 0.043 14.1 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 MerC mercury resistance protein SAC3_GANP PF03399.11 GAM26094.1 - 9.4e-35 120.0 4.6 1.7e-31 109.3 1.1 2.3 1 1 1 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Cohesin_HEAT PF12765.2 GAM26094.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Pox_F12L PF03337.8 GAM26094.1 - 0.059 11.2 0.1 0.08 10.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein Oxysterol_BP PF01237.13 GAM26095.1 - 2.2e-61 207.3 1.0 7.1e-61 205.6 0.7 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein UIM PF02809.15 GAM26096.1 - 0.044 13.3 0.4 0.14 11.7 0.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Macoilin PF09726.4 GAM26097.1 - 2.1 6.5 5.3 1.8 6.7 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein PTN_MK_N PF05196.8 GAM26097.1 - 7.1 6.6 8.7 0.57 10.1 2.2 2.0 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, N-terminal domain PIP5K PF01504.13 GAM26099.1 - 3.4e-64 216.3 11.5 1.7e-39 135.4 2.1 2.4 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.24 GAM26099.1 - 1.5e-16 60.5 2.5 2.8e-15 56.3 0.0 2.9 3 1 0 3 3 3 1 PH domain PH_11 PF15413.1 GAM26099.1 - 1.8e-05 24.9 3.9 9.8e-05 22.5 0.5 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.1 GAM26099.1 - 9e-05 22.4 0.0 0.00028 20.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 GAM26099.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain CAF-1_p150 PF11600.3 GAM26099.1 - 3.4 6.9 4.0 5.5 6.3 2.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Myb_DNA-binding PF00249.26 GAM26100.1 - 8.9e-26 89.6 7.3 2.7e-13 49.7 0.6 3.9 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM26100.1 - 2.4e-24 85.2 5.6 7.1e-14 51.6 0.2 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain DUF1981 PF09324.5 GAM26100.1 - 0.00048 19.6 0.2 0.0012 18.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Myb_DNA-bind_4 PF13837.1 GAM26100.1 - 0.0064 16.5 13.0 0.12 12.4 0.2 3.8 3 1 1 4 4 4 2 Myb/SANT-like DNA-binding domain MNE1 PF13762.1 GAM26100.1 - 0.032 14.2 0.3 0.077 13.0 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component Ribosomal_S3Ae PF01015.13 GAM26100.1 - 0.045 13.0 1.8 4.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Ribosomal S3Ae family DUF3029 PF11230.3 GAM26100.1 - 0.052 11.7 0.1 0.077 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Myb_DNA-bind_5 PF13873.1 GAM26100.1 - 0.39 10.6 6.6 17 5.3 0.0 4.4 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain RhoGEF PF00621.15 GAM26101.1 - 1.5e-43 148.7 5.8 1.5e-43 148.7 4.0 3.5 2 1 1 3 3 3 1 RhoGEF domain IQ PF00612.22 GAM26101.1 - 0.0055 16.2 3.1 0.015 14.8 2.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-UBR PF02207.15 GAM26102.1 - 2.1e-16 59.4 19.5 2.1e-16 59.4 13.5 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) CTF_NFI PF00859.13 GAM26102.1 - 0.036 13.8 1.4 0.073 12.8 1.0 1.4 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region SSP160 PF06933.6 GAM26102.1 - 0.93 7.3 7.1 1.4 6.8 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Arginase PF00491.16 GAM26104.1 - 8.1e-55 186.0 0.3 9e-55 185.9 0.2 1.0 1 0 0 1 1 1 1 Arginase family FMO-like PF00743.14 GAM26105.1 - 2e-21 75.8 0.1 9.6e-21 73.5 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM26105.1 - 7.1e-20 71.9 0.0 1.8e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM26105.1 - 3.4e-13 49.2 0.1 4.4e-11 42.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 GAM26105.1 - 1.1e-08 34.9 0.0 2.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM26105.1 - 1.6e-06 28.1 0.0 0.0017 18.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM26105.1 - 0.0002 21.1 0.0 0.18 11.5 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding BRX_N PF13713.1 GAM26105.1 - 0.063 12.7 0.1 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain GIDA PF01134.17 GAM26105.1 - 0.15 10.8 0.1 3.4 6.4 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A FNIP PF05725.7 GAM26109.1 - 5e-48 160.7 8.2 2.5e-15 56.1 0.8 4.3 2 1 2 4 4 4 4 FNIP Repeat Peptidase_M16 PF00675.15 GAM26110.1 - 1.2e-37 128.9 4.0 2.9e-36 124.4 0.2 2.5 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 GAM26110.1 - 1.8e-25 89.7 4.7 3e-14 53.0 0.0 4.1 5 1 0 5 5 5 2 Peptidase M16 inactive domain Dopey_N PF04118.9 GAM26111.1 - 3.2e-88 295.4 1.3 3.2e-88 295.4 0.9 3.5 3 0 0 3 3 3 2 Dopey, N-terminal G8 PF10162.4 GAM26112.1 - 1.1e-27 96.3 0.1 5.1e-27 94.1 0.1 2.3 1 0 0 1 1 1 1 G8 domain CBM_4_9 PF02018.12 GAM26112.1 - 0.0013 18.7 0.1 0.0059 16.6 0.0 2.1 1 0 0 1 1 1 1 Carbohydrate binding domain FNIP PF05725.7 GAM26113.1 - 2e-31 107.6 0.6 7.7e-12 44.9 0.1 5.8 5 0 0 5 5 5 5 FNIP Repeat bZIP_1 PF00170.16 GAM26113.1 - 0.026 14.4 1.6 0.031 14.2 0.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 GAM26113.1 - 0.47 10.3 2.8 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 Basic region leucine zipper FNIP PF05725.7 GAM26114.1 - 1.5e-30 104.9 14.3 6e-13 48.5 1.9 4.3 3 1 0 4 4 4 4 FNIP Repeat Gal4_dimer PF03902.8 GAM26114.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Gal4-like dimerisation domain Ank_2 PF12796.2 GAM26115.1 - 0.091 13.1 0.2 6.1 7.2 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) NAP PF00956.13 GAM26116.1 - 2.5e-44 151.2 0.2 3.7e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FliX PF10768.4 GAM26116.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Class II flagellar assembly regulator Cation_efflux PF01545.16 GAM26117.1 - 2.1e-60 204.2 5.8 2.6e-60 203.8 4.0 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3816 PF12822.2 GAM26117.1 - 0.09 12.6 8.2 0.14 12.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) TauE PF01925.14 GAM26117.1 - 0.42 10.0 5.5 0.53 9.6 0.9 2.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Zip PF02535.17 GAM26118.1 - 3e-40 138.1 7.9 6.3e-40 137.1 5.5 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Dicty_REP PF05086.7 GAM26118.1 - 0.094 10.4 0.8 0.13 9.9 0.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4190 PF13828.1 GAM26118.1 - 0.11 11.9 2.7 1.7 8.2 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4190) Pkinase PF00069.20 GAM26119.1 - 1.2e-65 221.2 0.0 3.7e-65 219.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26119.1 - 5.2e-30 104.3 0.0 5.7e-23 81.3 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.19 GAM26119.1 - 1.8e-19 69.5 0.4 1.1e-18 67.0 0.3 2.4 1 0 0 1 1 1 1 PX domain PH PF00169.24 GAM26119.1 - 3.5e-17 62.5 1.2 8.3e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 GAM26119.1 - 5.5e-06 25.5 0.1 0.00016 20.7 0.0 2.6 2 0 0 2 2 2 1 Kinase-like PH_8 PF15409.1 GAM26119.1 - 4e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 GAM26119.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family PH_11 PF15413.1 GAM26119.1 - 0.0058 16.8 0.4 0.0058 16.8 0.3 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain GtrA PF04138.9 GAM26121.1 - 0.0022 17.9 0.2 0.0058 16.5 0.1 1.7 2 0 0 2 2 2 1 GtrA-like protein Ank_2 PF12796.2 GAM26122.1 - 0.01 16.1 0.0 1.7 8.9 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) DUF1241 PF06840.6 GAM26124.1 - 0.0088 15.2 7.0 0.54 9.4 0.4 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1241) IGR PF09597.5 GAM26124.1 - 0.016 15.0 0.3 3.5 7.5 0.1 3.0 2 0 0 2 2 2 0 IGR protein motif zf-C2H2 PF00096.21 GAM26124.1 - 7.1 7.1 16.1 2.9 8.4 1.5 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type GED PF02212.13 GAM26125.1 - 0.064 13.1 1.3 2.6 7.9 0.0 3.3 3 0 0 3 3 3 0 Dynamin GTPase effector domain Ank_2 PF12796.2 GAM26126.1 - 0.014 15.6 0.8 0.37 11.1 0.1 3.3 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM26127.1 - 0.014 15.7 0.1 0.95 9.8 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) CTK3 PF12243.3 GAM26127.1 - 0.094 12.3 1.9 0.69 9.5 0.3 2.5 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 YebF PF13995.1 GAM26130.1 - 0.023 14.6 0.3 0.81 9.7 0.1 2.3 2 0 0 2 2 2 0 YebF-like protein DUF1395 PF07160.7 GAM26131.1 - 0.017 14.6 0.7 0.02 14.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) UvrD_C PF13361.1 GAM26131.1 - 0.03 13.7 3.0 0.037 13.4 2.1 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain FliH PF02108.11 GAM26132.1 - 0.014 15.2 1.7 0.17 11.7 0.0 3.3 3 0 0 3 3 3 0 Flagellar assembly protein FliH Sod_Ni PF09055.6 GAM26132.1 - 0.087 13.2 4.8 0.058 13.7 0.9 2.6 3 0 0 3 3 3 0 Nickel-containing superoxide dismutase Abhydrolase_6 PF12697.2 GAM26133.1 - 3e-27 95.9 0.0 3.5e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM26133.1 - 1.9e-22 79.5 2.2 2.2e-21 76.1 1.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 GAM26133.1 - 0.001 18.7 0.1 0.0031 17.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_1 PF00561.15 GAM26133.1 - 0.094 12.2 1.0 3.8 7.0 0.2 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_M41 PF01434.13 GAM26134.1 - 1.1e-64 217.8 5.6 1.9e-64 217.0 3.8 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAM26134.1 - 1.4e-43 148.2 0.6 2.5e-42 144.1 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM26134.1 - 4.5e-06 26.4 0.7 3.9e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAM26134.1 - 1.2e-05 25.2 0.2 0.0004 20.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 GAM26134.1 - 1.4e-05 25.8 0.5 0.00056 20.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM26134.1 - 1.7e-05 23.9 0.0 4.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 GAM26134.1 - 4.5e-05 23.4 0.3 0.00083 19.3 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 GAM26134.1 - 4.9e-05 23.6 1.0 0.001 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM26134.1 - 6.8e-05 22.0 0.0 0.00018 20.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAM26134.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 GAM26134.1 - 0.00014 22.0 2.2 0.0039 17.3 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 GAM26134.1 - 0.00018 20.9 0.2 0.0053 16.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 GAM26134.1 - 0.00026 20.9 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 GAM26134.1 - 0.0004 19.2 0.0 0.00081 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 GAM26134.1 - 0.0016 18.1 0.1 0.0051 16.5 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 GAM26134.1 - 0.0018 18.1 0.1 0.0064 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM26134.1 - 0.0034 16.5 0.2 0.011 14.9 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 GAM26134.1 - 0.013 15.7 1.1 0.082 13.2 0.0 2.6 2 1 1 3 3 3 0 ABC transporter AAA_24 PF13479.1 GAM26134.1 - 0.014 15.0 0.4 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 GAM26134.1 - 0.016 15.1 1.0 0.022 14.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 GAM26134.1 - 0.035 14.2 0.0 0.093 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 GAM26134.1 - 0.036 13.5 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 GAM26134.1 - 0.06 12.5 0.3 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 GAM26134.1 - 0.087 12.4 0.1 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain zf-CSL PF05207.8 GAM26135.1 - 2.7e-24 84.4 1.8 2.7e-24 84.4 1.3 1.5 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_5 PF13719.1 GAM26135.1 - 0.0028 17.1 0.2 0.0047 16.4 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 GAM26135.1 - 0.0039 16.8 0.5 0.0071 16.0 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.1 GAM26135.1 - 0.13 11.8 2.8 0.36 10.4 2.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TFIIS_C PF01096.13 GAM26135.1 - 2.1 8.0 4.9 2.4 7.8 0.3 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) NatB_MDM20 PF09797.4 GAM26136.1 - 1.4e-66 224.7 4.2 1.4e-66 224.7 2.9 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Apc3 PF12895.2 GAM26136.1 - 1.6e-10 40.9 10.4 1e-05 25.5 1.5 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 GAM26136.1 - 2.3e-09 36.7 0.4 0.0052 16.3 0.0 3.9 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 GAM26136.1 - 3.7e-09 36.7 5.5 0.026 14.8 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26136.1 - 3.4e-06 26.5 0.3 0.51 10.3 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM26136.1 - 0.00055 19.4 5.5 0.43 10.2 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26136.1 - 0.0013 19.1 0.0 13 6.7 0.0 5.2 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26136.1 - 0.0014 19.2 0.0 6.2 7.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26136.1 - 0.0083 16.5 0.1 4.2 8.0 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 GAM26136.1 - 0.27 11.2 3.3 22 5.3 0.1 3.9 5 0 0 5 5 5 0 PPR repeat TPR_8 PF13181.1 GAM26136.1 - 0.35 10.7 6.7 6.6 6.7 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Amastin PF07344.6 GAM26137.1 - 0.0063 16.1 4.1 0.0063 16.1 2.8 2.4 2 1 1 3 3 3 1 Amastin surface glycoprotein DUF2700 PF10912.3 GAM26137.1 - 0.025 14.5 0.4 0.047 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) DUF3353 PF11833.3 GAM26137.1 - 0.36 10.2 0.1 0.36 10.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) Pox_A9 PF04835.7 GAM26137.1 - 2.5 8.0 6.6 0.77 9.7 0.3 2.6 2 0 0 2 2 2 0 A9 protein conserved region SYS1 PF09801.4 GAM26138.1 - 1.9e-47 160.8 11.0 2.3e-47 160.6 7.6 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF307 PF03733.8 GAM26138.1 - 0.089 13.2 2.8 1.1 9.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF307) EI24 PF07264.6 GAM26138.1 - 0.39 10.1 6.8 0.57 9.5 4.7 1.3 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Na_Ala_symp PF01235.12 GAM26138.1 - 0.63 8.5 5.5 0.76 8.2 3.8 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family Rrp15p PF07890.7 GAM26139.1 - 5.4e-18 65.3 10.4 5.4e-18 65.3 7.2 2.6 2 1 0 2 2 2 1 Rrp15p Hairpins PF04877.7 GAM26139.1 - 0.076 12.4 3.7 0.14 11.5 2.5 1.3 1 0 0 1 1 1 0 HrpZ Stk19 PF10494.4 GAM26139.1 - 0.19 11.0 4.7 0.37 10.1 2.3 2.0 1 1 1 2 2 2 0 Serine-threonine protein kinase 19 Asn_synthase PF00733.16 GAM26140.1 - 0.39 10.1 7.6 0.25 10.7 3.4 2.0 1 1 1 2 2 2 0 Asparagine synthase Coatomer_WDAD PF04053.9 GAM26141.1 - 1.5e-160 534.8 0.7 6e-160 532.8 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 GAM26141.1 - 2.6e-52 172.9 3.4 1.7e-12 46.7 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 GAM26141.1 - 0.038 12.1 0.8 2 6.4 0.3 2.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TPR_8 PF13181.1 GAM26141.1 - 0.079 12.7 0.1 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 GAM26142.1 - 2.9e-34 118.4 0.0 3.8e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26142.1 - 3.5e-13 49.2 0.0 6.3e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM26142.1 - 0.0082 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 GAM26142.1 - 0.046 12.4 0.1 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UQ_con PF00179.21 GAM26143.1 - 2.4e-51 172.8 0.1 2.7e-51 172.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 GAM26144.1 - 7.3e-69 231.8 0.5 1.2e-68 231.0 0.3 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26144.1 - 3.3e-26 91.9 0.1 5.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM26144.1 - 7.4e-09 34.9 0.0 2.3e-08 33.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 GAM26144.1 - 7.5e-05 22.5 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 GAM26144.1 - 9.4e-05 21.5 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM26144.1 - 0.0018 17.6 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF1168 PF06658.7 GAM26145.1 - 1.3e-29 102.5 22.6 1.5e-29 102.3 15.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) FLO_LFY PF01698.11 GAM26145.1 - 0.84 8.4 12.3 0.81 8.4 8.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 GAM26145.1 - 5 6.9 10.3 7 6.4 7.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_11 PF13086.1 GAM26146.1 - 1.4e-58 198.2 0.0 1.4e-58 198.2 0.0 3.4 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.1 GAM26146.1 - 1.7e-54 184.2 0.0 1.7e-54 184.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain R3H PF01424.17 GAM26146.1 - 5e-14 51.7 0.5 2e-13 49.7 0.1 2.3 2 0 0 2 2 2 1 R3H domain AAA_19 PF13245.1 GAM26146.1 - 1.4e-12 47.1 0.0 3e-11 42.8 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 GAM26146.1 - 2.3e-09 37.1 0.0 1.3e-07 31.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain zf-AN1 PF01428.11 GAM26146.1 - 5.7e-06 26.1 4.0 5.7e-06 26.1 2.8 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger AAA_16 PF13191.1 GAM26146.1 - 0.00012 22.1 0.1 0.00055 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 GAM26146.1 - 0.0014 17.8 0.0 0.0044 16.1 0.0 1.8 1 0 0 1 1 1 1 KaiC Zot PF05707.7 GAM26146.1 - 0.0032 16.9 0.1 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_25 PF13481.1 GAM26146.1 - 0.004 16.5 0.0 0.013 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM26146.1 - 0.015 15.4 4.5 0.036 14.2 0.2 3.5 3 1 0 3 3 2 0 AAA domain AAA PF00004.24 GAM26146.1 - 0.023 14.9 1.4 0.099 12.8 0.9 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 GAM26146.1 - 0.042 14.1 0.1 0.042 14.1 0.0 2.9 2 2 1 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.13 GAM26146.1 - 0.082 12.3 1.1 0.24 10.8 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 GAM26146.1 - 0.6 10.9 4.6 0.44 11.3 0.2 3.0 3 0 0 3 3 3 0 AAA domain SSP160 PF06933.6 GAM26146.1 - 1.2 7.0 9.8 1.9 6.3 6.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BioY PF02632.9 GAM26147.1 - 2.4e-05 24.0 1.7 3.1e-05 23.6 1.2 1.1 1 0 0 1 1 1 1 BioY family MLANA PF14991.1 GAM26147.1 - 0.029 14.3 3.5 0.031 14.3 0.8 2.1 1 1 1 2 2 2 0 Protein melan-A Yip1 PF04893.12 GAM26147.1 - 0.051 13.0 5.0 0.07 12.6 3.5 1.2 1 0 0 1 1 1 0 Yip1 domain DUF1469 PF07332.6 GAM26147.1 - 0.15 11.8 1.7 0.21 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Pox_A14 PF05767.7 GAM26147.1 - 0.57 10.1 4.3 1 9.3 3.0 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2207 PF09972.4 GAM26147.1 - 6.1 5.3 8.6 9.4 4.6 5.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Tetraspannin PF00335.15 GAM26147.1 - 9 5.5 18.6 0.12 11.6 4.6 2.1 2 0 0 2 2 2 0 Tetraspanin family UBX PF00789.15 GAM26148.1 - 2.1e-10 40.4 0.0 4.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 GAM26148.1 - 6.7e-05 22.8 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like REJ PF02010.10 GAM26148.1 - 0.037 12.3 0.2 0.045 12.0 0.1 1.1 1 0 0 1 1 1 0 REJ domain DUF4207 PF13904.1 GAM26148.1 - 0.057 12.7 10.8 0.087 12.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Asp-B-Hydro_N PF05279.6 GAM26148.1 - 0.21 11.3 13.2 0.3 10.9 9.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HAUS6_N PF14661.1 GAM26148.1 - 3.4 6.9 10.1 4.8 6.4 7.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FNIP PF05725.7 GAM26150.1 - 2.3e-78 257.9 38.8 1.6e-14 53.5 0.9 9.5 5 3 5 10 10 10 10 FNIP Repeat LRR_7 PF13504.1 GAM26150.1 - 0.88 10.0 5.5 13 6.4 0.0 5.0 6 0 0 6 6 6 0 Leucine rich repeat Ank_2 PF12796.2 GAM26151.1 - 5.4e-44 148.4 27.4 3.6e-09 36.8 0.4 7.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26151.1 - 4.6e-40 134.7 16.5 0.00098 19.2 0.1 15.2 4 2 12 16 16 16 12 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM26151.1 - 5.4e-40 135.0 14.8 4.3e-06 27.0 0.1 10.8 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26151.1 - 5.8e-30 100.3 14.8 0.12 12.6 0.0 15.6 7 4 9 16 16 16 7 Ankyrin repeat Ank PF00023.25 GAM26151.1 - 1.3e-23 81.5 13.6 2.1 8.2 0.0 15.0 13 3 2 16 16 16 8 Ankyrin repeat DUF2493 PF10686.4 GAM26151.1 - 0.00091 18.7 14.0 1.8 8.1 0.0 7.0 3 3 3 7 7 7 1 Protein of unknown function (DUF2493) Peptidase_C23 PF05379.6 GAM26151.1 - 0.0027 17.6 1.3 8.3 6.4 0.0 5.0 5 1 1 6 6 6 1 Carlavirus endopeptidase Rbsn PF11464.3 GAM26151.1 - 0.0095 15.4 0.7 41 3.8 0.0 6.3 9 0 0 9 9 9 0 Rabenosyn Rab binding domain zf-4CXXC_R1 PF10497.4 GAM26151.1 - 0.14 12.3 4.0 27 4.9 0.0 5.6 6 3 3 9 9 9 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF1707 PF08044.6 GAM26151.1 - 0.6 9.9 3.9 18 5.1 0.0 4.8 5 1 1 6 6 6 0 Domain of unknown function (DUF1707) Syja_N PF02383.13 GAM26152.1 - 2.2e-37 128.5 1.5 2.2e-37 128.5 1.0 2.1 2 0 0 2 2 2 1 SacI homology domain FYVE PF01363.16 GAM26152.1 - 0.0013 18.5 8.6 0.0027 17.5 6.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 GAM26152.1 - 0.2 11.5 7.5 0.44 10.4 5.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.16 GAM26152.1 - 0.22 11.4 14.1 0.071 12.9 7.0 2.1 1 1 1 2 2 2 0 IBR domain DAGK_cat PF00781.19 GAM26153.1 - 4.4e-27 94.0 0.0 7.8e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 GAM26153.1 - 0.00031 19.6 0.0 0.00063 18.6 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase zf-Nse PF11789.3 GAM26154.1 - 9.5e-21 73.0 0.6 1.7e-20 72.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 GAM26154.1 - 1.2e-07 31.2 0.3 3.4e-07 29.8 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 GAM26154.1 - 9.6e-06 25.0 0.2 1.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Rtf2 PF04641.7 GAM26154.1 - 0.00079 18.7 3.2 0.00079 18.7 2.2 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 GAM26154.1 - 0.0028 17.2 0.1 0.0067 16.0 0.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM26154.1 - 0.023 14.5 0.1 0.055 13.3 0.0 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 GAM26154.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM26154.1 - 0.058 13.4 0.5 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HTH_43 PF09904.4 GAM26154.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix zf-RING_2 PF13639.1 GAM26154.1 - 0.085 12.7 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Mss51 PF13824.1 GAM26154.1 - 7.3 6.5 6.1 2.7 7.9 0.6 2.8 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Med21 PF11221.3 GAM26155.1 - 5.5e-21 75.0 3.6 7.6e-21 74.6 2.5 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF4574 PF15141.1 GAM26155.1 - 0.01 15.5 2.0 0.021 14.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) DUF2935 PF11155.3 GAM26155.1 - 0.04 14.0 0.6 0.058 13.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Cauli_AT PF03233.8 GAM26155.1 - 0.079 12.6 3.0 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 Aphid transmission protein adh_short PF00106.20 GAM26156.1 - 4.1e-26 91.8 0.0 5.4e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM26156.1 - 2.3e-10 40.6 0.1 3.1e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 GAM26156.1 - 6.6e-08 32.4 0.0 9.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM26156.1 - 4.7e-05 23.4 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 GAM26156.1 - 0.021 13.7 0.2 0.035 12.9 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM26156.1 - 0.037 13.4 0.3 0.12 11.8 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CTC1 PF15489.1 GAM26158.1 - 0.002 15.6 0.6 0.0046 14.3 0.4 1.5 1 1 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 p450 PF00067.17 GAM26160.1 - 1e-86 291.3 0.1 1.1e-86 291.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_20 PF00728.17 GAM26161.1 - 2.3e-88 296.7 2.3 3e-88 296.3 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM26161.1 - 4.6e-17 62.8 0.1 1.1e-16 61.6 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM26161.1 - 0.0012 19.3 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribosomal_L21p PF00829.16 GAM26162.1 - 8.8e-29 99.5 0.6 1.9e-28 98.4 0.4 1.6 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Paramyxo_C PF01692.13 GAM26162.1 - 0.00062 19.4 1.5 0.00091 18.9 1.0 1.3 1 0 0 1 1 1 1 Paramyxovirus non-structural protein c Mucin PF01456.12 GAM26162.1 - 0.012 15.3 13.8 0.021 14.6 9.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 GAM26162.1 - 0.2 11.4 8.2 0.4 10.4 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM26162.1 - 1.4 6.7 14.9 1.8 6.4 10.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMEM154 PF15102.1 GAM26162.1 - 6.9 6.3 9.8 0.5 10.0 3.4 1.6 2 0 0 2 2 2 0 TMEM154 protein family Fip1 PF05182.8 GAM26163.1 - 2.6e-23 80.9 2.0 4.6e-23 80.2 1.4 1.4 1 0 0 1 1 1 1 Fip1 motif GlcNAc PF11397.3 GAM26164.1 - 3.5e-72 243.3 0.0 4.3e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) TGT PF01702.13 GAM26165.1 - 1.2e-67 227.6 0.1 1.5e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Kelch_3 PF13415.1 GAM26166.1 - 3.4e-40 135.3 22.1 2.3e-10 40.3 0.1 8.5 9 0 0 9 9 9 5 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM26166.1 - 2e-34 117.1 10.5 1e-08 34.8 0.2 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM26166.1 - 6.9e-34 115.2 6.8 5.3e-10 39.0 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 GAM26166.1 - 5.4e-31 105.8 0.3 3.3e-08 32.9 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM26166.1 - 7.2e-29 98.7 6.4 2.4e-07 30.6 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM26166.1 - 6.2e-23 79.6 4.2 0.002 17.8 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Atrophin-1 PF03154.10 GAM26166.1 - 8.2e-05 20.9 19.3 8.2e-05 20.9 13.4 2.5 2 0 0 2 2 2 1 Atrophin-1 family Trypan_PARP PF05887.6 GAM26166.1 - 0.53 10.1 12.5 1.2 8.9 8.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 GAM26166.1 - 1.1 8.6 20.9 2.9 7.2 14.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1777 PF08648.7 GAM26166.1 - 5.3 6.7 28.7 0.076 12.7 13.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1777) RhoGAP PF00620.22 GAM26167.1 - 7e-25 87.4 0.1 9.8e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain TGS PF02824.16 GAM26168.1 - 4.7e-21 74.3 0.1 9.3e-21 73.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAM26168.1 - 2.2e-18 66.2 0.1 4.1e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM26168.1 - 6.3e-11 41.7 0.0 1.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 GAM26168.1 - 0.00079 19.2 0.5 0.5 10.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 GAM26168.1 - 0.0048 15.7 0.1 0.011 14.4 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 GAM26168.1 - 0.009 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 GAM26168.1 - 0.039 13.3 0.4 18 4.7 0.1 3.6 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM26168.1 - 0.1 11.7 0.1 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit WD40 PF00400.27 GAM26170.1 - 1e-70 231.3 19.6 1.1e-12 47.2 0.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM26170.1 - 0.00031 19.0 5.9 1 7.3 0.1 4.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 GAM26170.1 - 0.00044 20.0 0.2 0.028 14.1 0.0 2.9 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 GAM26170.1 - 0.002 16.9 8.3 0.43 9.2 0.2 4.7 1 1 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 GAM26170.1 - 0.025 14.2 0.1 1.3 8.7 0.0 3.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat RhoGAP PF00620.22 GAM26171.1 - 2.5e-26 92.1 5.2 1.3e-16 60.6 0.0 3.1 2 1 1 3 3 3 2 RhoGAP domain DUF605 PF04652.11 GAM26171.1 - 0.19 11.1 21.3 0.35 10.2 14.8 1.4 1 0 0 1 1 1 0 Vta1 like BAR PF03114.13 GAM26171.1 - 0.74 9.2 7.5 0.12 11.8 1.7 2.3 2 2 0 2 2 2 0 BAR domain Epimerase PF01370.16 GAM26172.1 - 1.1e-53 182.0 0.0 1.4e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 GAM26172.1 - 5.9e-29 99.8 1.1 1.2e-28 98.7 0.8 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 GAM26172.1 - 2.2e-14 53.0 0.0 5.2e-13 48.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 GAM26172.1 - 2.4e-13 49.4 0.0 6.2e-13 48.0 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 GAM26172.1 - 6.5e-11 41.6 0.0 1.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 GAM26172.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 GAM26172.1 - 3.3e-08 32.7 0.0 1.8e-06 27.0 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein KR PF08659.5 GAM26172.1 - 8.5e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM26172.1 - 1.1e-05 25.4 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM26172.1 - 0.0053 16.0 0.1 0.89 8.7 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family DALR_1 PF05746.10 GAM26173.1 - 1.8e-08 34.3 0.2 1.8e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 DALR anticodon binding domain FNIP PF05725.7 GAM26174.1 - 1.4e-79 261.7 29.8 9.1e-13 47.9 0.1 10.1 6 2 2 10 10 10 10 FNIP Repeat FNIP PF05725.7 GAM26175.1 - 3.7e-79 260.4 22.2 9.7e-14 51.0 0.0 8.1 4 1 5 9 9 9 9 FNIP Repeat Myb_DNA-binding PF00249.26 GAM26175.1 - 7.1e-09 35.5 0.4 1.7e-08 34.3 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM26175.1 - 0.00064 19.7 1.4 0.0021 18.1 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Usher PF00577.15 GAM26176.1 - 0.0058 15.4 2.0 0.0075 15.0 1.4 1.1 1 0 0 1 1 1 1 Outer membrane usher protein Mucin PF01456.12 GAM26176.1 - 0.1 12.3 29.7 0.19 11.4 20.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_CAR PF05462.6 GAM26177.1 - 4.7e-135 449.3 29.1 5.7e-135 449.0 20.2 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM26177.1 - 3.5e-06 26.2 21.5 5.2e-06 25.7 14.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PDEase_II PF02112.10 GAM26178.1 - 5e-82 275.5 0.1 6.1e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAM26178.1 - 0.00032 20.3 0.0 0.00097 18.7 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UQ_con PF00179.21 GAM26179.1 - 9.4e-36 122.3 0.0 1.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3552 PF12072.3 GAM26180.1 - 1.2 8.3 4.4 1.8 7.7 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TRAP_alpha PF03896.11 GAM26180.1 - 5.6 5.8 10.0 10 5.0 6.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF914 PF06027.7 GAM26182.1 - 1.2e-09 37.5 14.4 1.2e-09 37.5 10.0 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 GAM26182.1 - 1.8e-07 31.2 41.9 1.1e-05 25.4 1.4 3.5 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 GAM26182.1 - 1.5e-06 27.8 29.9 0.0011 18.6 7.8 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 GAM26182.1 - 0.00024 21.2 0.8 0.00024 21.2 0.6 3.6 3 1 1 4 4 4 1 Multidrug resistance efflux transporter WD40 PF00400.27 GAM26183.1 - 1.3e-64 211.8 24.5 1e-10 41.0 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Alpha_kinase PF02816.13 GAM26183.1 - 1.1e-61 207.8 1.6 2e-61 206.9 1.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family Nup160 PF11715.3 GAM26183.1 - 1e-12 47.0 12.3 0.0011 17.1 0.6 5.9 1 1 4 6 6 6 4 Nucleoporin Nup120/160 PQQ_3 PF13570.1 GAM26183.1 - 9.4e-05 22.5 0.0 59 4.1 0.0 5.7 6 0 0 6 6 6 0 PQQ-like domain PQQ_2 PF13360.1 GAM26183.1 - 0.0051 16.3 0.1 2 7.8 0.0 3.3 2 1 0 2 2 2 1 PQQ-like domain Ion_trans PF00520.26 GAM26184.1 - 8.1e-30 103.5 59.1 9.2e-20 70.7 21.7 2.8 3 0 0 3 3 3 2 Ion transport protein EF-hand_7 PF13499.1 GAM26184.1 - 4.3e-08 33.1 1.0 2.4e-05 24.3 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM26184.1 - 2.5e-05 23.2 2.6 0.01 15.0 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 GAM26184.1 - 0.00016 21.2 7.6 0.082 12.8 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 GAM26184.1 - 0.014 14.9 0.4 0.056 13.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair PP2C PF00481.16 GAM26185.1 - 4.7e-51 173.6 0.0 1.4e-50 172.0 0.0 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM26185.1 - 0.0015 18.2 0.1 2.4 7.8 0.0 2.8 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) MbeD_MobD PF04899.7 GAM26185.1 - 0.08 12.8 2.9 0.16 11.8 0.7 2.4 2 0 0 2 2 2 0 MbeD/MobD like HlyD PF00529.15 GAM26185.1 - 1 8.6 13.9 1.7 7.8 9.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Jnk-SapK_ap_N PF09744.4 GAM26185.1 - 2 8.3 16.9 6.6 6.7 11.6 1.9 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 LIM PF00412.17 GAM26186.1 - 1.5e-25 89.0 29.6 2.1e-13 50.1 8.8 2.1 2 0 0 2 2 2 2 LIM domain DUF2688 PF10892.3 GAM26186.1 - 0.072 12.7 0.2 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Mu-like_Com PF10122.4 GAM26186.1 - 0.18 10.8 11.7 0.4 9.7 0.2 3.5 3 0 0 3 3 3 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.1 GAM26186.1 - 0.34 10.1 19.4 0.79 9.0 0.4 4.6 4 1 0 4 4 4 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 GAM26186.1 - 0.75 9.5 12.4 1.5 8.5 0.0 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS NMD3 PF04981.8 GAM26186.1 - 0.85 8.6 16.8 0.28 10.2 3.0 2.4 2 1 0 2 2 2 0 NMD3 family Zn-ribbon_8 PF09723.5 GAM26186.1 - 0.94 9.4 18.9 2.7 8.0 0.1 4.5 4 1 0 4 4 4 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.11 GAM26186.1 - 4.5 7.0 7.6 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain WH1 PF00568.18 GAM26187.1 - 2.4e-22 78.7 0.2 3.6e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 GAM26187.1 - 0.0015 18.8 2.4 0.0023 18.3 0.1 2.4 2 0 0 2 2 2 1 P21-Rho-binding domain DCP1 PF06058.8 GAM26187.1 - 0.0085 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF1681 PF07933.9 GAM26187.1 - 0.018 14.6 0.5 0.03 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) UPF0370 PF13980.1 GAM26187.1 - 0.056 13.2 0.7 0.056 13.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DUF2076 PF09849.4 GAM26187.1 - 1.4 8.9 6.3 0.06 13.3 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) WH1 PF00568.18 GAM26188.1 - 3.2e-23 81.5 0.5 4.8e-23 80.9 0.4 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 GAM26188.1 - 1.2e-14 54.4 0.1 3.6e-14 52.9 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 GAM26188.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 WH2 motif DUF1681 PF07933.9 GAM26188.1 - 0.022 14.3 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) DCP1 PF06058.8 GAM26188.1 - 0.05 13.6 0.2 0.079 13.0 0.1 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family PAT1 PF09770.4 GAM26188.1 - 0.055 11.7 28.6 0.069 11.3 19.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GCS PF03074.11 GAM26189.1 - 3.2e-162 539.8 1.5 4.2e-162 539.4 1.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF3567 PF12091.3 GAM26189.1 - 0.027 14.4 0.0 2.2 8.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) LSM PF01423.17 GAM26190.1 - 1.7e-16 59.4 0.0 2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM26190.1 - 0.14 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain A_deamin PF02137.13 GAM26192.1 - 3.4e-94 315.9 2.8 2.1e-93 313.3 1.9 1.9 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Mucin PF01456.12 GAM26192.1 - 0.0042 16.8 11.8 0.009 15.7 8.2 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 GAM26192.1 - 0.79 9.4 12.5 1.7 8.4 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FANCI_S2 PF14676.1 GAM26193.1 - 3.5e-34 117.9 2.6 8.6e-34 116.7 0.2 3.0 2 0 0 2 2 2 1 FANCI solenoid 2 FANCI_HD2 PF14680.1 GAM26193.1 - 8.3e-33 113.4 2.3 8.3e-33 113.4 1.6 3.0 2 1 0 2 2 2 1 FANCI helical domain 2 FANCI_S4 PF14678.1 GAM26193.1 - 4.3e-22 78.4 8.0 4.3e-22 78.4 5.5 3.8 4 1 1 5 5 5 1 FANCI solenoid 4 FANCI_S1 PF14675.1 GAM26193.1 - 1.9e-16 60.1 3.0 1.9e-16 60.1 2.1 2.3 2 0 0 2 2 2 1 FANCI solenoid 1 FANCI_HD1 PF14679.1 GAM26193.1 - 3.6e-10 39.4 0.0 2e-09 37.0 0.0 2.4 1 0 0 1 1 1 1 FANCI helical domain 1 DUF3584 PF12128.3 GAM26194.1 - 0.13 9.5 21.7 0.16 9.2 15.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mitofilin PF09731.4 GAM26194.1 - 0.57 8.7 20.2 0.68 8.5 14.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mem_trans PF03547.13 GAM26194.1 - 0.73 8.0 6.1 0.81 7.9 4.2 1.2 1 0 0 1 1 1 0 Membrane transport protein PA26 PF04636.8 GAM26194.1 - 0.94 8.0 11.4 0.94 8.1 7.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1223 PF06764.6 GAM26194.1 - 1 9.1 9.7 1.6 8.5 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Ycf1 PF05758.7 GAM26194.1 - 3.7 5.1 16.7 4.2 4.9 11.5 1.1 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 GAM26194.1 - 3.8 7.3 13.8 5.1 6.9 9.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.3 GAM26194.1 - 4.1 6.0 20.2 5.6 5.6 14.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 GAM26194.1 - 5.4 6.3 25.3 0.28 10.5 14.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SprA-related PF12118.3 GAM26194.1 - 8.1 5.6 25.4 12 5.1 17.6 1.2 1 0 0 1 1 1 0 SprA-related family SAPS PF04499.10 GAM26194.1 - 8.6 4.8 14.4 9.5 4.7 10.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Calcipressin PF04847.7 GAM26195.1 - 2.5e-10 40.2 1.0 7.9e-10 38.6 0.3 1.9 1 1 1 2 2 2 1 Calcipressin 4_1_CTD PF05902.8 GAM26195.1 - 0.062 13.3 0.1 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 4.1 protein C-terminal domain (CTD) IQ PF00612.22 GAM26196.1 - 4.2e-06 25.9 13.0 0.0011 18.3 0.4 3.1 3 0 0 3 3 3 2 IQ calmodulin-binding motif PuR_N PF09182.5 GAM26196.1 - 0.46 10.1 4.2 0.46 10.1 0.6 2.3 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Tnp_zf-ribbon_2 PF13842.1 GAM26197.1 - 7.3 7.0 9.0 8.2 6.9 1.1 2.6 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon CUB_2 PF02408.15 GAM26198.1 - 0.0057 16.1 0.2 0.013 15.0 0.1 1.5 1 1 0 1 1 1 1 CUB-like domain Gypsy PF07253.6 GAM26198.1 - 0.0098 14.2 0.1 0.013 13.8 0.1 1.1 1 0 0 1 1 1 1 Gypsy protein Bactofilin PF04519.8 GAM26198.1 - 0.021 14.8 0.3 0.044 13.8 0.2 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal DUF4098 PF13345.1 GAM26198.1 - 0.71 9.8 5.0 2.7 7.9 1.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) RasGEF PF00617.14 GAM26201.1 - 6.5e-48 162.9 0.2 1.7e-47 161.6 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain GRAM PF02893.15 GAM26201.1 - 2.3e-11 43.0 0.3 5.3e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 GRAM domain RhoGAP PF00620.22 GAM26201.1 - 5.4e-10 39.0 0.0 1.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Y_phosphatase2 PF03162.8 GAM26203.1 - 3.5e-42 143.5 0.0 3.5e-42 143.5 0.0 1.9 2 1 0 2 2 2 1 Tyrosine phosphatase family Mem_trans PF03547.13 GAM26203.1 - 0.016 13.5 2.0 0.018 13.3 1.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Y_phosphatase3 PF13350.1 GAM26203.1 - 0.054 13.7 2.7 0.42 10.8 0.0 2.5 2 1 0 2 2 2 0 Tyrosine phosphatase family Neur_chan_memb PF02932.11 GAM26203.1 - 0.11 12.3 3.2 0.15 11.9 2.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 GAM26203.1 - 0.78 8.0 15.7 0.99 7.7 10.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.1 GAM26203.1 - 2.5 7.7 9.9 5 6.8 6.9 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Dicty_REP PF05086.7 GAM26203.1 - 4.9 4.7 17.4 0.3 8.8 8.5 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Activator_LAG-3 PF11498.3 GAM26203.1 - 7.9 5.1 38.1 12 4.5 26.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 C1_1 PF00130.17 GAM26204.1 - 1.7e-12 46.8 23.8 5e-08 32.5 4.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Serglycin PF04360.7 GAM26204.1 - 0.00084 19.0 0.5 0.00084 19.0 0.3 4.3 3 2 0 3 3 3 1 Serglycin DUF1049 PF06305.6 GAM26205.1 - 0.0036 16.7 0.1 0.0049 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Vpu PF00558.14 GAM26205.1 - 0.031 13.8 0.4 0.046 13.2 0.3 1.3 1 0 0 1 1 1 0 Vpu protein DUF621 PF04789.10 GAM26206.1 - 0.0093 15.0 1.1 0.016 14.1 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF621) Lipase_3 PF01764.20 GAM26207.1 - 1.7e-38 131.4 0.0 2.5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM26207.1 - 4.6e-05 22.9 0.1 0.00022 20.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 GAM26207.1 - 0.00061 19.5 0.0 0.0011 18.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 GAM26207.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 GAM26207.1 - 0.028 13.9 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 GAM26207.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 GAM26207.1 - 0.052 13.4 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_A2E PF12382.3 GAM26208.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon peptidase Ras PF00071.17 GAM26209.1 - 1.2e-18 67.0 0.0 2.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Ras family LRR_6 PF13516.1 GAM26209.1 - 2.7e-17 60.8 13.3 0.01 15.7 0.0 6.8 7 0 0 7 7 7 5 Leucine Rich repeat Miro PF08477.8 GAM26209.1 - 1e-10 42.1 0.0 1e-10 42.1 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein LRR_4 PF12799.2 GAM26209.1 - 2.1e-08 33.5 6.5 0.00055 19.4 0.2 3.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM26209.1 - 0.0004 20.0 3.9 6.5 7.1 0.0 4.8 5 0 0 5 5 4 2 Leucine Rich Repeat Ycf1 PF05758.7 GAM26209.1 - 0.0029 15.4 10.2 0.0039 14.9 7.0 1.3 1 0 0 1 1 1 1 Ycf1 LRR_7 PF13504.1 GAM26209.1 - 0.0031 17.4 3.8 23 5.7 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat GAGA_bind PF06217.7 GAM26209.1 - 0.1 12.5 16.1 0.16 11.8 11.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF262 PF03235.9 GAM26209.1 - 0.22 11.4 7.2 0.37 10.7 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 GTP_EFTU PF00009.22 GAM26209.1 - 0.37 10.2 11.8 0.11 11.9 4.2 2.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Borrelia_P83 PF05262.6 GAM26209.1 - 0.42 8.8 25.8 0.63 8.2 17.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CAF-1_p150 PF11600.3 GAM26209.1 - 0.5 9.7 43.5 0.99 8.7 30.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LRR_8 PF13855.1 GAM26209.1 - 2.3 8.0 9.7 3.9 7.3 0.5 3.8 3 2 0 3 3 3 0 Leucine rich repeat NUDIX PF00293.23 GAM26210.1 - 5.9e-18 64.8 0.0 1.1e-17 63.9 0.0 1.3 2 0 0 2 2 2 1 NUDIX domain Ribosomal_S17 PF00366.15 GAM26211.1 - 2.4e-27 94.7 1.0 3.3e-27 94.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Erp_C PF06780.6 GAM26212.1 - 0.021 14.6 2.2 0.028 14.2 1.5 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Racemase_4 PF13615.1 GAM26212.1 - 0.038 14.2 0.1 0.07 13.3 0.1 1.4 1 1 0 1 1 1 0 Putative alanine racemase DUF4298 PF14131.1 GAM26212.1 - 0.088 12.6 1.1 0.11 12.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) ArfGap PF01412.13 GAM26213.1 - 5e-35 119.7 1.0 5e-35 119.7 0.7 3.0 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf DUF2514 PF10721.4 GAM26213.1 - 6.2 6.5 5.8 0.67 9.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Ank_2 PF12796.2 GAM26214.1 - 2.3e-12 47.0 9.4 0.005 17.1 0.1 8.4 7 3 1 8 8 8 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26214.1 - 5.4e-05 23.3 1.0 5 7.5 0.0 7.3 7 1 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26214.1 - 0.0009 19.2 13.7 65 4.2 0.0 11.0 13 0 0 13 13 13 0 Ankyrin repeat Ank_4 PF13637.1 GAM26214.1 - 0.0015 19.0 9.1 14 6.3 0.1 8.7 8 2 2 10 10 10 1 Ankyrin repeats (many copies) Glyco_hydro_31 PF01055.21 GAM26216.1 - 1.4e-167 558.0 6.5 2.2e-167 557.3 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM26216.1 - 2.8e-08 33.4 0.3 2.8e-08 33.4 0.2 2.9 4 0 0 4 4 4 1 Galactose mutarotase-like FA_hydroxylase PF04116.8 GAM26217.1 - 1.8e-18 67.0 13.3 1.8e-18 67.0 9.2 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ABC2_membrane_4 PF12730.2 GAM26220.1 - 0.0019 17.3 9.7 0.0023 17.1 6.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF373 PF04123.8 GAM26220.1 - 0.068 12.1 4.7 0.077 12.0 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1106 PF06523.6 GAM26220.1 - 0.53 10.1 2.0 0.41 10.5 0.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1106) PrgI PF12666.2 GAM26220.1 - 2.5 8.3 8.6 0.16 12.1 1.0 2.1 1 1 1 2 2 2 0 PrgI family protein DUF4181 PF13789.1 GAM26220.1 - 4.6 7.2 7.8 5.4 6.9 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) Rap_GAP PF02145.10 GAM26221.1 - 2.7e-59 199.7 0.0 3.8e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP DUF162 PF02589.10 GAM26222.1 - 3.6e-25 88.5 0.0 4.2e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YkgG family COG1556 NHL PF01436.16 GAM26222.1 - 0.011 15.6 0.5 0.14 12.2 0.0 2.8 3 0 0 3 3 3 0 NHL repeat DUF1204 PF06721.6 GAM26222.1 - 0.13 11.5 0.2 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) HpcH_HpaI PF03328.9 GAM26223.1 - 3.5e-45 153.6 0.8 2.9e-44 150.6 0.5 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 GAM26223.1 - 3.4e-19 68.8 0.1 7.4e-11 41.4 0.0 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold BtpA PF03437.10 GAM26223.1 - 0.024 13.8 0.6 0.38 9.9 0.4 2.1 1 1 0 1 1 1 0 BtpA family Globin PF00042.17 GAM26224.1 - 2.9e-08 34.0 0.0 5.5e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Globin Protoglobin PF11563.3 GAM26224.1 - 0.01 15.5 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 0 Protoglobin Phage_antiter_Q PF06323.6 GAM26224.1 - 0.078 12.3 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q DUF373 PF04123.8 GAM26225.1 - 0.1 11.6 3.8 0.12 11.3 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4234 PF14018.1 GAM26225.1 - 0.1 12.3 6.2 0.23 11.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) RasGEF PF00617.14 GAM26230.1 - 9.5e-35 120.0 0.2 1.7e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM26230.1 - 2.8e-16 59.5 0.2 7.8e-16 58.0 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif TIG PF01833.19 GAM26230.1 - 6.3e-12 45.3 17.8 4e-06 26.7 1.0 3.8 3 0 0 3 3 3 2 IPT/TIG domain Adeno_E3_CR2 PF02439.10 GAM26230.1 - 0.0036 16.8 0.6 0.0093 15.4 0.4 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 GAM26230.1 - 0.0037 16.9 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 GAM26230.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3481 PF11980.3 GAM26230.1 - 0.024 14.4 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) stn_TNFRSF12A PF12191.3 GAM26230.1 - 0.049 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF1191 PF06697.7 GAM26230.1 - 0.053 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Orthoreo_P10 PF07204.6 GAM26230.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 SapB_1 PF05184.10 GAM26231.1 - 9.1e-22 76.3 8.7 1e-11 44.3 1.0 2.9 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 GAM26231.1 - 2e-12 46.8 9.9 5.1e-06 26.3 0.5 4.0 4 0 0 4 4 4 2 Saposin-like type B, region 2 PWI PF01480.12 GAM26231.1 - 0.03 14.4 0.2 0.25 11.4 0.1 2.5 2 1 0 2 2 2 0 PWI domain NosL PF05573.7 GAM26231.1 - 0.25 11.0 2.9 5.7 6.6 0.1 2.6 2 1 1 3 3 3 0 NosL Coronavirus_5 PF05528.6 GAM26231.1 - 0.89 9.4 5.2 4 7.3 0.2 3.0 3 1 1 4 4 4 0 Coronavirus gene 5 protein Lung_7-TM_R PF06814.8 GAM26232.1 - 1.3e-15 57.1 12.7 1.3e-15 57.1 8.8 2.2 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 GAM26232.1 - 1.9e-05 23.9 10.8 1.9e-05 23.9 7.5 2.0 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain RR_TM4-6 PF06459.7 GAM26232.1 - 0.00074 19.4 1.3 0.00074 19.4 0.9 1.6 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 CENP-T PF15511.1 GAM26232.1 - 0.2 10.8 16.5 0.26 10.4 11.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2782 PF11191.3 GAM26232.1 - 2.2 8.3 4.3 3 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) Hid1 PF12722.2 GAM26232.1 - 4.3 4.8 11.8 7 4.1 8.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DASH_Dad4 PF08650.5 GAM26233.1 - 0.11 12.4 1.8 0.13 12.1 1.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pkinase PF00069.20 GAM26234.1 - 4.3e-68 229.2 0.0 6.4e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26234.1 - 3.3e-47 160.7 0.1 5e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM26234.1 - 5e-05 23.1 0.0 0.013 15.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 GAM26234.1 - 0.00027 20.3 0.1 0.0005 19.4 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 GAM26234.1 - 0.0017 17.3 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM26234.1 - 0.034 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAM26234.1 - 0.046 13.2 0.1 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase CDC27 PF09507.5 GAM26234.1 - 1.7 7.7 16.2 2.5 7.2 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sgf11 PF08209.6 GAM26235.1 - 1.5e-07 30.5 0.2 2.6e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Methyltransf_11 PF08241.7 GAM26236.1 - 3.2e-13 49.9 0.0 5.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM26236.1 - 7.2e-11 42.0 0.0 9.7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM26236.1 - 7.1e-10 39.4 0.0 1.1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM26236.1 - 8.3e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM26236.1 - 6.3e-08 33.0 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM26236.1 - 8.9e-06 26.0 0.0 1.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 GAM26236.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 GAM26236.1 - 0.028 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 GAM26236.1 - 0.061 12.6 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain PQ-loop PF04193.9 GAM26238.1 - 2.1e-08 33.5 1.5 4.8e-08 32.4 1.0 1.6 1 0 0 1 1 1 1 PQ loop repeat RasGEF PF00617.14 GAM26239.1 - 1.3e-61 207.5 0.1 3.7e-61 206.1 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM26239.1 - 5.9e-22 77.7 0.5 5.9e-22 77.7 0.3 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif FERM_N PF09379.5 GAM26239.1 - 9.4e-06 25.6 1.0 0.031 14.3 0.0 3.5 3 0 0 3 3 3 2 FERM N-terminal domain Rad60-SLD PF11976.3 GAM26239.1 - 0.00091 18.8 2.8 17 5.1 0.0 5.7 5 0 0 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.18 GAM26239.1 - 0.0025 18.2 0.0 0.79 10.2 0.0 4.3 4 1 1 5 5 5 1 Ras association (RalGDS/AF-6) domain DUF3439 PF11921.3 GAM26239.1 - 0.43 10.3 10.5 1 9.0 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_C12 PF01088.16 GAM26240.1 - 0.1 11.7 0.9 0.13 11.4 0.6 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Rifin_STEVOR PF02009.11 GAM26240.1 - 0.36 10.4 10.7 0.38 10.3 7.4 1.0 1 0 0 1 1 1 0 Rifin/stevor family DUF4400 PF14348.1 GAM26240.1 - 0.58 9.5 5.2 0.64 9.3 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) NPR3 PF03666.8 GAM26240.1 - 0.66 8.4 6.1 0.73 8.2 4.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4228 PF14009.1 GAM26240.1 - 5.1 7.2 8.7 7.3 6.6 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Plasmodium_Vir PF05795.6 GAM26240.1 - 8.5 5.4 10.5 9.9 5.2 7.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MDFI PF15316.1 GAM26240.1 - 9.5 6.1 8.9 12 5.8 6.2 1.2 1 0 0 1 1 1 0 MyoD family inhibitor RNase_T PF00929.19 GAM26241.1 - 5.9e-16 59.1 0.0 9.4e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 GAM26241.1 - 0.0046 16.4 0.0 0.015 14.7 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease ACOX PF01756.14 GAM26242.1 - 4.2e-38 130.5 0.0 6.9e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 GAM26242.1 - 3.9e-16 59.4 0.0 8e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 GAM26242.1 - 1.6e-09 37.1 0.2 7.2e-09 35.0 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM26242.1 - 0.023 14.7 0.2 0.39 10.8 0.0 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Dicty_REP PF05086.7 GAM26243.1 - 0.34 8.6 2.2 0.32 8.7 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAM26243.1 - 5.2 6.8 13.3 7.8 6.2 9.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_C1 PF00112.18 GAM26244.1 - 6.6e-63 212.5 3.4 7.9e-63 212.2 2.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 GAM26244.1 - 6.3e-09 35.3 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.10 GAM26244.1 - 1.5e-05 23.7 1.6 0.00068 18.2 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family AAA PF00004.24 GAM26245.1 - 6e-38 130.0 0.0 1.2e-37 129.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM26245.1 - 1e-06 28.4 0.1 3.6e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM26245.1 - 1.1e-06 28.7 0.6 0.00096 19.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 GAM26245.1 - 1.5e-06 29.0 0.1 4.1e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM26245.1 - 2.2e-06 27.7 0.3 0.00053 20.0 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 GAM26245.1 - 2.9e-06 26.5 0.0 1.2e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAM26245.1 - 1.3e-05 25.1 0.1 3.4e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM26245.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM26245.1 - 3.4e-05 24.1 0.3 0.00017 21.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM26245.1 - 4.5e-05 23.1 0.0 0.00033 20.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 GAM26245.1 - 0.00024 20.8 0.1 0.003 17.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 GAM26245.1 - 0.00025 20.5 0.0 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 GAM26245.1 - 0.00033 20.2 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 GAM26245.1 - 0.001 17.8 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 GAM26245.1 - 0.0013 17.8 0.1 0.0034 16.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 GAM26245.1 - 0.0014 17.7 0.2 0.0029 16.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 GAM26245.1 - 0.0021 18.1 0.0 0.012 15.7 0.0 2.2 1 1 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 GAM26245.1 - 0.0026 17.2 0.1 0.008 15.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.9 GAM26245.1 - 0.0028 17.5 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAM26245.1 - 0.0072 15.2 0.2 0.015 14.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 GAM26245.1 - 0.0084 15.0 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 GAM26245.1 - 0.011 15.4 0.1 2.1 8.0 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 GAM26245.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM26245.1 - 0.018 14.4 1.7 0.058 12.7 0.1 2.3 2 1 0 3 3 3 0 AAA domain PhoH PF02562.11 GAM26245.1 - 0.02 14.1 0.1 0.041 13.1 0.1 1.5 1 1 0 1 1 1 0 PhoH-like protein SKI PF01202.17 GAM26245.1 - 0.034 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 GAM26245.1 - 0.041 12.7 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 GAM26245.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAM26245.1 - 0.048 13.9 0.2 0.098 12.9 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 GAM26245.1 - 0.056 13.0 0.0 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 GAM26245.1 - 0.063 12.3 0.1 0.16 11.0 0.0 1.6 1 1 1 2 2 2 0 KaiC ResIII PF04851.10 GAM26245.1 - 0.084 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 GAM26245.1 - 0.092 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAM26245.1 - 0.092 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 GAM26245.1 - 0.1 12.2 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein DUF572 PF04502.8 GAM26246.1 - 5.7e-57 193.3 2.0 6.2e-57 193.2 1.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) RRP7 PF12923.2 GAM26246.1 - 0.1 12.5 7.9 0.26 11.2 5.5 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) NAC PF01849.13 GAM26247.1 - 3.7e-16 58.3 0.0 1.1e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 NAC domain FinO_N PF12602.3 GAM26247.1 - 0.0066 16.7 0.1 0.14 12.4 0.1 2.1 2 0 0 2 2 2 1 Fertility inhibition protein N terminal Yip1 PF04893.12 GAM26248.1 - 7.1e-14 51.6 15.0 1.4e-13 50.7 10.3 1.5 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.10 GAM26248.1 - 0.037 13.1 5.3 0.06 12.4 3.7 1.3 1 0 0 1 1 1 0 YIF1 Ank_2 PF12796.2 GAM26251.1 - 0.001 19.3 1.9 1.3 9.4 0.0 4.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) HTH_45 PF14947.1 GAM26251.1 - 0.043 13.6 1.1 0.22 11.3 0.2 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix Ank_2 PF12796.2 GAM26252.1 - 0.0024 18.1 0.0 0.018 15.3 0.0 2.0 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26252.1 - 0.058 13.6 0.4 9.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Proteasome PF00227.21 GAM26253.1 - 3.8e-60 202.4 0.4 6.7e-60 201.6 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM26253.1 - 1e-15 56.6 0.1 2.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature FYVE_2 PF02318.11 GAM26253.1 - 0.66 9.8 2.4 1.1 9.1 1.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger WD40 PF00400.27 GAM26254.1 - 5.6e-53 175.0 11.3 1.8e-09 37.1 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 GAM26254.1 - 0.011 14.5 1.6 0.28 9.8 0.1 3.0 1 1 0 2 2 2 0 Nup133 N terminal like eIF-4B PF06273.6 GAM26254.1 - 0.047 12.4 2.2 0.067 11.9 1.5 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B WD40 PF00400.27 GAM26255.1 - 3.3e-30 102.8 20.2 5.3e-06 26.1 0.2 8.5 7 0 0 7 7 7 7 WD domain, G-beta repeat UME PF08064.8 GAM26255.1 - 0.018 15.0 0.4 0.088 12.7 0.2 2.2 2 0 0 2 2 2 0 UME (NUC010) domain Pkinase PF00069.20 GAM26256.1 - 4.8e-62 209.4 0.0 6.4e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26256.1 - 1.2e-19 70.4 0.0 1.9e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM26256.1 - 1.2e-08 34.9 0.0 1.9e-07 31.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM26256.1 - 0.0073 15.3 0.0 0.27 10.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 GAM26256.1 - 0.014 14.7 0.8 2.9 7.1 0.0 2.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 GAM26256.1 - 0.017 14.7 0.2 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 GAM26256.1 - 0.065 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dicty_CTDC PF00526.13 GAM26257.1 - 1.6e-30 104.4 187.7 6.4e-09 35.4 8.1 13.2 13 1 0 13 13 13 12 Dictyostelium (slime mold) repeat Mtp PF03821.11 GAM26258.1 - 0.012 14.9 0.9 0.04 13.3 0.3 1.9 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter Amnionless PF14828.1 GAM26258.1 - 0.22 9.9 0.3 2.2 6.6 0.0 2.0 2 0 0 2 2 2 0 Amnionless Beta_helix PF13229.1 GAM26259.1 - 1e-06 28.6 44.4 0.00031 20.5 8.6 2.8 1 1 2 3 3 3 2 Right handed beta helix region Adeno_E3_CR2 PF02439.10 GAM26259.1 - 0.00053 19.4 5.2 0.00096 18.6 3.6 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.6 GAM26259.1 - 0.00066 19.2 1.3 0.0012 18.4 0.9 1.4 1 0 0 1 1 1 1 Podoplanin Protocadherin PF08374.6 GAM26259.1 - 0.022 14.3 3.4 0.033 13.8 1.3 1.9 2 0 0 2 2 2 0 Protocadherin SKG6 PF08693.5 GAM26259.1 - 0.025 13.8 9.2 0.054 12.8 6.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 GAM26259.1 - 0.38 11.1 3.6 0.75 10.2 2.5 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.13 GAM26259.1 - 0.64 9.7 6.1 0.18 11.5 1.9 2.0 2 1 0 2 2 2 0 Glycophorin A NosD PF05048.8 GAM26259.1 - 1.6 7.8 41.6 0.43 9.6 9.4 2.7 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Fork_head PF00250.13 GAM26262.1 - 0.0021 18.0 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Fork head domain UPF0104 PF03706.8 GAM26263.1 - 0.038 13.2 2.4 0.046 12.9 1.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF3290 PF11694.3 GAM26263.1 - 0.049 13.3 0.3 0.077 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) 2TM PF13239.1 GAM26263.1 - 0.14 12.2 3.8 0.3 11.1 2.7 1.5 1 0 0 1 1 1 0 2TM domain DUF1203 PF06718.6 GAM26263.1 - 0.35 10.6 3.6 0.33 10.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) PAT1 PF09770.4 GAM26263.1 - 6.7 4.8 25.7 7.8 4.5 17.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-AN1 PF01428.11 GAM26264.1 - 3e-12 46.1 8.1 3e-12 46.1 5.6 2.4 2 1 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 GAM26264.1 - 3.1e-11 42.6 6.3 9.7e-11 41.0 4.4 1.9 1 0 0 1 1 1 1 A20-like zinc finger tRNA_m1G_MT PF01746.16 GAM26265.1 - 7.6e-26 90.8 0.1 7.6e-26 90.8 0.1 2.3 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase Med3 PF11593.3 GAM26265.1 - 0.61 9.2 27.7 1.7 7.8 7.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal NOA36 PF06524.7 GAM26265.1 - 2.3 7.3 13.2 0.053 12.7 3.9 1.9 2 0 0 2 2 2 0 NOA36 protein Mucin PF01456.12 GAM26265.1 - 3.5 7.4 60.6 0.1 12.3 17.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein CAF-1_p150 PF11600.3 GAM26265.1 - 7.3 5.8 38.4 0.029 13.7 14.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RE_MamI PF09567.5 GAM26267.1 - 0.0032 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 MamI restriction endonuclease FYVE_2 PF02318.11 GAM26268.1 - 2 8.3 9.0 0.28 11.0 3.4 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger DUF892 PF05974.7 GAM26269.1 - 0.0025 17.6 0.9 0.0025 17.6 0.6 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF892) IncA PF04156.9 GAM26269.1 - 0.0044 16.6 0.9 0.0044 16.6 0.6 2.4 2 1 0 2 2 2 1 IncA protein Sporozoite_P67 PF05642.6 GAM26269.1 - 0.078 10.8 2.5 0.092 10.5 1.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PLRV_ORF5 PF01690.12 GAM26269.1 - 0.1 11.7 9.6 0.13 11.4 6.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SPX PF03105.14 GAM26269.1 - 0.16 11.7 16.0 0.21 11.3 11.1 1.1 1 0 0 1 1 1 0 SPX domain UPF0184 PF03670.8 GAM26269.1 - 0.52 10.5 15.2 0.57 10.4 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Paramyxo_ncap PF00973.14 GAM26269.1 - 1.5 7.4 8.1 2.2 6.9 5.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1510 PF07423.6 GAM26269.1 - 1.8 7.8 16.3 8.4 5.6 9.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TORC_M PF12885.2 GAM26269.1 - 5.2 6.8 9.0 0.37 10.5 2.8 1.7 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain DENN PF02141.16 GAM26270.1 - 4e-36 124.4 6.7 5.8e-36 123.9 4.6 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAM26270.1 - 3e-10 39.9 0.1 5.9e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 uDENN domain SPA PF08616.5 GAM26270.1 - 1.2e-05 24.9 0.5 2.8e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAM26270.1 - 0.00068 18.2 0.7 0.00093 17.7 0.5 1.2 1 0 0 1 1 1 1 Transport protein Avl9 LIM PF00412.17 GAM26272.1 - 2.5e-10 40.2 23.1 1.8e-07 31.0 4.6 2.9 2 1 1 3 3 3 2 LIM domain TNFR_c6 PF00020.13 GAM26272.1 - 0.34 11.0 16.2 0.18 11.9 1.1 3.5 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Serinc PF03348.10 GAM26273.1 - 9.6e-56 189.3 22.0 1.1e-55 189.0 15.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) LRR_6 PF13516.1 GAM26274.1 - 9e-20 68.4 43.6 0.00025 20.8 0.5 11.5 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.2 GAM26274.1 - 6.4e-16 57.5 32.8 0.00055 19.4 0.3 7.5 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM26274.1 - 3.3e-11 41.5 30.1 0.54 10.4 0.1 10.9 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_8 PF13855.1 GAM26274.1 - 5.1e-07 29.3 37.0 7.6e-05 22.3 3.7 7.4 2 2 6 8 8 8 7 Leucine rich repeat LRR_7 PF13504.1 GAM26274.1 - 6.9e-05 22.4 29.3 1.9 9.0 0.1 10.9 10 1 1 11 11 11 2 Leucine rich repeat DEAD PF00270.24 GAM26275.1 - 3.9e-19 68.7 0.0 1e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM26275.1 - 5.3e-12 45.9 0.0 5.3e-12 45.9 0.0 3.7 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 GAM26275.1 - 9.4e-07 28.6 0.1 3.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RRM_5 PF13893.1 GAM26276.1 - 9.3e-43 143.8 0.3 7.3e-18 64.1 0.1 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM26276.1 - 4.6e-28 96.9 0.0 1e-11 44.6 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM26276.1 - 2.1e-19 68.9 0.3 8.1e-07 28.5 0.0 5.3 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM26276.1 - 0.0035 17.0 0.0 3 7.6 0.0 3.3 3 0 0 3 3 3 2 Limkain b1 Chorein_N PF12624.2 GAM26277.1 - 5.2e-15 55.0 3.3 1.6e-14 53.4 1.4 2.5 1 1 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Lycopene_cycl PF05834.7 GAM26277.1 - 0.02 13.8 0.2 0.041 12.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N PF00107.21 GAM26278.1 - 3.5e-26 91.2 0.0 1.3e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM26278.1 - 7.3e-13 48.2 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 GAM26278.1 - 1.5e-05 25.8 0.1 6.8e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF4296 PF14129.1 GAM26278.1 - 0.0039 17.3 0.1 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4296) PALP PF00291.20 GAM26278.1 - 0.0074 15.5 0.5 0.014 14.6 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme NAD_binding_10 PF13460.1 GAM26278.1 - 0.043 13.8 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 GAM26278.1 - 0.055 13.0 0.1 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CHB_HEX_C PF03174.8 GAM26279.1 - 1.5e-16 60.0 7.9 1.5e-16 60.0 5.5 2.7 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 GAM26279.1 - 1.9e-13 50.2 8.6 4.9e-13 48.9 5.0 2.3 2 0 0 2 2 2 1 Fn3 associated CHB_HEX_C_1 PF13290.1 GAM26279.1 - 3.7e-13 49.0 7.3 3.7e-13 49.0 5.1 2.9 3 0 0 3 3 3 1 Chitobiase/beta-hexosaminidase C-terminal domain FliD_N PF02465.13 GAM26279.1 - 0.023 15.0 0.6 0.023 15.0 0.4 3.4 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PEGA PF08308.6 GAM26279.1 - 0.55 10.0 4.2 8.7 6.2 0.1 3.3 3 0 0 3 3 3 0 PEGA domain Mito_carr PF00153.22 GAM26282.1 - 3.9e-59 196.3 5.3 8.2e-21 73.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1539 PF07560.6 GAM26282.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) OTU PF02338.14 GAM26283.1 - 1.5e-12 48.1 0.0 1.5e-12 48.1 0.0 2.7 3 1 1 4 4 4 1 OTU-like cysteine protease WASH-7_C PF14746.1 GAM26283.1 - 1.3 8.5 11.3 2 8.0 2.8 2.4 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Syndecan PF01034.15 GAM26285.1 - 1.1 9.0 3.2 2.2 7.9 2.2 1.5 1 0 0 1 1 1 0 Syndecan domain CarboxypepD_reg PF13620.1 GAM26286.1 - 1.5e-45 153.1 20.2 7.3e-08 32.3 0.2 9.4 10 0 0 10 10 10 7 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 GAM26286.1 - 1.4e-23 82.4 19.1 0.0052 16.5 0.0 9.8 9 1 1 10 10 10 7 Cna protein B-type domain DUF4480 PF13715.1 GAM26286.1 - 3e-17 62.4 20.3 1.4e-05 25.0 0.1 8.0 7 1 1 8 8 8 4 Domain of unknown function (DUF4480) DUF2012 PF09430.5 GAM26286.1 - 2.9e-14 52.9 1.2 0.084 12.7 0.0 8.1 9 0 0 9 9 9 3 Protein of unknown function (DUF2012) fn3_3 PF14686.1 GAM26286.1 - 8.2e-12 45.0 5.1 0.1 12.6 0.0 7.9 8 0 0 8 8 8 3 Polysaccharide lyase family 4, domain II phage_tail_N PF08400.5 GAM26286.1 - 2.2e-05 24.1 8.0 0.052 13.2 0.0 6.2 8 0 0 8 8 8 1 Prophage tail fibre N-terminal Pollen_Ole_e_I PF01190.12 GAM26286.1 - 7.8e-05 22.4 5.5 0.11 12.3 0.0 5.1 5 0 0 5 5 5 1 Pollen proteins Ole e I like fn3 PF00041.16 GAM26286.1 - 0.00052 20.0 0.1 0.75 9.9 0.0 4.1 3 0 0 3 3 3 1 Fibronectin type III domain Dioxygenase_C PF00775.16 GAM26286.1 - 0.012 14.8 1.7 14 4.8 0.0 5.0 6 0 0 6 6 6 0 Dioxygenase Sec-ASP3 PF15432.1 GAM26286.1 - 0.03 14.2 1.4 0.14 12.1 0.0 2.9 3 0 0 3 3 3 0 Accessory Sec secretory system ASP3 SID-1_RNA_chan PF13965.1 GAM26287.1 - 0.05 11.7 1.5 0.053 11.6 1.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ETRAMP PF09716.5 GAM26287.1 - 0.065 13.1 0.4 0.065 13.1 0.3 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Secretin_N_2 PF07655.8 GAM26287.1 - 0.28 11.5 7.8 0.2 12.0 0.7 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Beta_helix PF13229.1 GAM26288.1 - 1.4e-05 24.9 23.2 2.2e-05 24.2 11.5 2.4 1 1 1 2 2 2 2 Right handed beta helix region DUF3557 PF12078.3 GAM26290.1 - 0.018 14.7 1.9 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3557) DUF1966 PF09260.6 GAM26290.1 - 0.21 11.6 2.8 0.86 9.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF1966) Response_reg PF00072.19 GAM26294.1 - 1.7e-20 73.0 0.2 6.2e-20 71.2 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain LRR_4 PF12799.2 GAM26294.1 - 2.9e-11 42.7 34.0 0.00082 18.9 0.7 6.7 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM26294.1 - 2.1e-08 33.4 40.7 0.8 9.9 0.2 10.7 10 1 1 11 11 11 6 Leucine Rich repeat LRR_8 PF13855.1 GAM26294.1 - 1.2e-06 28.1 36.0 0.00069 19.3 5.4 5.4 3 2 3 6 6 6 5 Leucine rich repeat SR-25 PF10500.4 GAM26294.1 - 0.0016 17.9 12.0 0.03 13.7 0.6 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein LRR_1 PF00560.28 GAM26294.1 - 0.0057 16.5 32.8 30 5.1 0.0 10.6 8 2 1 9 9 9 0 Leucine Rich Repeat TraG-D_C PF12696.2 GAM26294.1 - 1.2 9.0 7.2 0.98 9.2 0.9 2.4 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG UCH PF00443.24 GAM26295.1 - 5.7e-50 169.9 0.0 7.4e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM26295.1 - 8.8e-22 77.8 0.0 1.4e-20 73.9 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 GAM26295.1 - 8.1e-18 63.7 0.4 4.2e-10 39.1 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 GAM26295.1 - 5.7e-17 61.5 0.0 6.3e-15 55.0 0.0 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Ank_2 PF12796.2 GAM26296.1 - 2.6e-20 72.5 4.7 0.00022 21.5 0.0 9.1 3 3 5 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26296.1 - 7.9e-07 29.4 12.1 2.4 8.7 0.1 9.4 11 1 1 12 12 12 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26296.1 - 4.7e-06 26.6 4.6 9.8 6.5 0.0 8.0 8 0 0 8 8 8 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26296.1 - 0.00026 20.9 26.8 1.4 9.3 0.0 12.9 16 0 0 16 16 16 1 Ankyrin repeat Ank PF00023.25 GAM26296.1 - 0.073 12.9 18.5 27 4.8 0.1 8.7 9 1 0 9 9 9 0 Ankyrin repeat TFIIA PF03153.8 GAM26297.1 - 6.2 6.6 23.6 4.3 7.1 4.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TAF PF02969.12 GAM26299.1 - 0.04 13.8 0.7 0.1 12.5 0.3 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Methyltransf_26 PF13659.1 GAM26300.1 - 5.2e-14 52.2 0.0 7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM26300.1 - 2.6e-09 36.6 0.0 3.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 GAM26300.1 - 0.00066 19.2 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM26300.1 - 0.00087 18.4 0.0 0.42 9.6 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 GAM26300.1 - 0.0047 17.3 0.0 0.031 14.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM26300.1 - 0.0054 16.2 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_24 PF13578.1 GAM26300.1 - 0.0091 16.8 0.0 0.025 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM26300.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DUF1269 PF06897.7 GAM26300.1 - 0.091 12.7 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) p450 PF00067.17 GAM26301.1 - 1e-102 344.1 0.0 1.2e-102 343.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Podoplanin PF05808.6 GAM26302.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Podoplanin VSP PF03302.8 GAM26302.1 - 0.74 8.3 7.5 0.25 9.9 3.3 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein PCI_Csn8 PF10075.4 GAM26303.1 - 2.4e-23 82.5 1.8 2.4e-23 82.5 1.2 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAM26303.1 - 2.1e-11 43.7 4.9 3.2e-11 43.1 3.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 GAM26303.1 - 0.00017 21.8 0.6 0.00045 20.4 0.4 1.7 1 0 0 1 1 1 1 PCI domain UPF0118 PF01594.11 GAM26303.1 - 0.13 11.2 1.4 0.14 11.0 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF20 Ank_4 PF13637.1 GAM26304.1 - 1.1e-20 73.6 1.0 2.6e-07 30.9 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26304.1 - 1.6e-17 63.0 0.6 5.7e-09 35.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26304.1 - 1.3e-16 60.7 0.4 3.1e-08 33.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26304.1 - 1.1e-15 56.4 0.0 4.9e-08 32.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 GAM26304.1 - 3.2e-11 42.3 0.0 3.7e-05 23.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF3881 PF12997.2 GAM26304.1 - 0.16 10.9 0.6 10 5.0 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) Glyco_hydro_31 PF01055.21 GAM26305.1 - 8.7e-166 552.1 3.0 1.1e-165 551.8 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM26305.1 - 4.9e-11 42.3 0.4 1.7e-10 40.5 0.2 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 GAM26306.1 - 3.9e-68 229.7 23.5 1.8e-44 151.9 4.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM26306.1 - 1e-19 70.2 20.7 5.2e-11 41.5 1.3 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 GAM26306.1 - 1.4e-15 56.8 22.4 2.5e-14 52.7 2.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 GAM26306.1 - 8.5e-08 30.7 15.3 4.8e-05 21.6 10.0 2.9 1 1 1 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.14 GAM26306.1 - 8.2e-07 27.9 22.4 2.5e-05 23.0 1.2 3.4 3 1 0 3 3 3 2 LacY proton/sugar symporter MFS_1_like PF12832.2 GAM26306.1 - 0.00015 21.4 9.1 0.2 11.4 0.0 4.2 4 1 0 4 4 4 2 MFS_1 like family OATP PF03137.15 GAM26306.1 - 0.00024 19.3 0.5 0.00024 19.3 0.3 3.6 2 2 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_Omp PF13488.1 GAM26306.1 - 0.08 12.5 2.9 0.23 11.1 2.0 1.7 1 0 0 1 1 1 0 Glycine zipper EphA2_TM PF14575.1 GAM26306.1 - 0.22 11.9 0.8 2.1 8.8 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pam17 PF08566.5 GAM26306.1 - 1 9.0 7.7 7.1 6.2 0.3 3.0 2 2 1 3 3 3 0 Mitochondrial import protein Pam17 FNIP PF05725.7 GAM26307.1 - 1.8e-09 37.3 4.0 0.035 14.0 0.0 5.2 3 2 2 5 5 5 5 FNIP Repeat Dus PF01207.12 GAM26310.1 - 4.2e-71 239.3 0.0 5.7e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 GAM26310.1 - 0.00073 18.6 0.1 0.0021 17.1 0.1 1.8 1 1 0 1 1 1 1 Thiamine monophosphate synthase/TENI DUF561 PF04481.7 GAM26310.1 - 0.00079 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Oxidored_FMN PF00724.15 GAM26310.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DHO_dh PF01180.16 GAM26310.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 GAM26310.1 - 0.067 12.4 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Synaptobrevin PF00957.16 GAM26311.1 - 7.5e-12 44.6 1.6 4.8e-11 42.0 0.7 2.0 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 GAM26311.1 - 9.4e-07 28.2 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gp-FAR-1 PF05823.7 GAM26311.1 - 0.0072 16.2 0.4 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) 7tm_3 PF00003.17 GAM26312.1 - 2.6e-38 131.7 25.1 4e-38 131.1 17.4 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.23 GAM26312.1 - 3.6e-38 131.2 0.8 5.9e-38 130.5 0.5 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.1 GAM26312.1 - 2.8e-12 46.6 2.3 4.5e-12 45.9 1.6 1.2 1 0 0 1 1 1 1 Periplasmic binding protein SNARE_assoc PF09335.6 GAM26313.1 - 9.5e-22 77.5 6.6 9.5e-22 77.5 4.6 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein Ndc1_Nup PF09531.5 GAM26314.1 - 0.13 10.6 12.1 0.022 13.2 2.1 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup EF-hand_7 PF13499.1 GAM26315.1 - 1.2e-41 140.7 16.9 1.1e-07 31.9 0.1 7.4 4 3 2 6 6 6 6 EF-hand domain pair EF-hand_6 PF13405.1 GAM26315.1 - 1.4e-40 133.4 10.7 0.0015 18.2 0.1 10.4 10 0 0 10 10 10 10 EF-hand domain EF-hand_1 PF00036.27 GAM26315.1 - 3.3e-40 132.3 16.1 0.0033 16.6 0.0 10.3 10 0 0 10 10 10 10 EF hand EF-hand_5 PF13202.1 GAM26315.1 - 3.2e-32 108.4 25.1 0.00049 19.3 0.0 10.2 10 0 0 10 10 10 9 EF hand EF-hand_8 PF13833.1 GAM26315.1 - 2e-23 81.7 18.9 0.18 11.4 0.2 10.3 10 0 0 10 10 10 9 EF-hand domain pair EF-hand_9 PF14658.1 GAM26315.1 - 3.1e-10 39.8 1.0 1.6 8.6 0.0 7.9 8 1 1 9 9 8 2 EF-hand domain SPARC_Ca_bdg PF10591.4 GAM26315.1 - 1.2e-07 31.7 7.6 19 5.3 0.1 7.7 5 3 3 8 8 8 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM26315.1 - 2.8e-05 23.6 0.0 30 4.3 0.0 6.6 10 0 0 10 10 10 0 EF hand Phage_hub_GP28 PF11110.3 GAM26315.1 - 0.02 14.5 0.1 2.8 7.6 0.0 3.3 4 0 0 4 4 4 0 Baseplate hub distal subunit PAH PF02671.16 GAM26315.1 - 0.022 14.3 0.2 25 4.5 0.0 4.4 5 0 0 5 5 5 0 Paired amphipathic helix repeat GSH-S_N PF02951.9 GAM26315.1 - 0.045 13.5 6.7 3.4 7.4 0.1 4.3 5 0 0 5 5 5 0 Prokaryotic glutathione synthetase, N-terminal domain DNA_methylase PF00145.12 GAM26315.1 - 0.066 12.3 9.9 1.2 8.1 1.1 3.2 1 1 2 3 3 3 0 C-5 cytosine-specific DNA methylase Peptidase_S3 PF00944.14 GAM26315.1 - 0.075 12.4 0.0 59 3.0 0.0 3.3 3 0 0 3 3 3 0 Alphavirus core protein DUF3192 PF11399.3 GAM26315.1 - 0.16 11.8 2.2 51 3.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3192) HisK_N PF09385.5 GAM26315.1 - 0.34 10.5 5.2 4.4 6.9 0.1 3.2 4 0 0 4 4 4 0 Histidine kinase N terminal Pex14_N PF04695.8 GAM26315.1 - 7 6.7 32.1 0.89 9.6 6.0 4.2 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0552 PF10574.4 GAM26317.1 - 1.3e-48 165.3 0.1 1.5e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0552 Cyclin PF08613.6 GAM26318.1 - 3e-31 108.8 0.3 3e-31 108.8 0.2 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM26318.1 - 2e-12 46.8 0.1 4e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAXNEB PF05625.6 GAM26318.1 - 0.016 14.0 0.2 0.016 14.0 0.2 1.9 2 1 0 2 2 2 0 PAXNEB protein AF-4 PF05110.8 GAM26318.1 - 0.77 7.5 13.0 1 7.1 9.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.4 GAM26318.1 - 0.81 7.8 8.4 1.1 7.5 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 GAM26318.1 - 3.2 7.7 8.9 0.63 10.0 2.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 GAM26319.1 - 3.6e-53 180.3 0.0 8.7e-53 179.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26319.1 - 9.5e-52 175.6 0.1 1.5e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 GAM26319.1 - 1.8e-18 66.7 0.2 5e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain APH PF01636.18 GAM26319.1 - 0.016 14.9 0.1 0.51 10.0 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Adenosine_kin PF04008.9 GAM26320.1 - 0.024 14.1 0.0 0.08 12.4 0.0 1.8 2 0 0 2 2 2 0 Adenosine specific kinase Myosin_tail_1 PF01576.14 GAM26321.1 - 0.00072 17.4 47.2 0.00072 17.4 32.7 2.1 1 1 1 2 2 2 1 Myosin tail FERM_N PF09379.5 GAM26321.1 - 0.0011 18.9 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 FERM N-terminal domain AAA_13 PF13166.1 GAM26321.1 - 0.0022 16.5 7.9 0.0022 16.5 5.5 3.2 1 1 2 3 3 3 2 AAA domain Spc7 PF08317.6 GAM26321.1 - 0.0031 16.2 11.6 0.0031 16.2 8.0 3.7 1 1 3 4 4 4 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 GAM26321.1 - 0.0065 16.3 22.6 0.0065 16.3 15.7 5.5 1 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 GAM26321.1 - 0.16 11.8 5.2 0.14 12.0 1.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 GAM26321.1 - 0.34 10.0 16.1 0.43 9.7 1.7 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 GAM26321.1 - 1.3 8.4 65.0 0.023 14.1 14.3 3.0 1 1 1 2 2 2 0 Intermediate filament protein MAD PF05557.8 GAM26321.1 - 2.2 6.2 66.7 7.2e+02 -2.1 46.3 2.6 1 1 0 1 1 1 0 Mitotic checkpoint protein ATG16 PF08614.6 GAM26321.1 - 3.1 7.5 59.2 0.023 14.5 18.1 4.5 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) IncA PF04156.9 GAM26321.1 - 7.8 6.0 71.1 0.4 10.2 7.5 4.5 1 1 3 4 4 4 0 IncA protein Fer2 PF00111.22 GAM26323.1 - 8.2e-15 54.3 0.1 1.1e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4097 PF13349.1 GAM26323.1 - 0.037 13.5 0.1 0.091 12.3 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4097) DUF1364 PF07102.7 GAM26323.1 - 0.046 13.5 0.2 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Fer2_4 PF13510.1 GAM26323.1 - 0.047 13.4 0.4 0.16 11.7 0.3 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DnaJ-X PF14308.1 GAM26324.1 - 4.9e-28 97.7 2.3 6.7e-28 97.3 1.6 1.2 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAM26325.1 - 2e-27 94.6 2.3 2.8e-27 94.2 1.6 1.2 1 0 0 1 1 1 1 DnaJ domain HSP70 PF00012.15 GAM26326.1 - 3e-250 831.3 12.6 3.6e-250 831.0 8.7 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM26326.1 - 1e-14 53.9 3.1 7.7e-12 44.4 0.1 2.8 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 GAM26326.1 - 3.1e-05 23.6 0.0 0.008 15.8 0.0 3.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 GAM26326.1 - 0.0025 17.6 13.9 0.44 10.4 0.1 5.2 4 2 0 4 4 4 2 Cell division protein FtsA DUF4363 PF14276.1 GAM26326.1 - 0.12 12.0 3.3 0.26 10.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 GAM26326.1 - 2.2 7.2 9.9 0.36 9.8 0.0 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Podoplanin PF05808.6 GAM26327.1 - 0.0023 17.5 0.2 0.0054 16.3 0.1 1.7 1 0 0 1 1 1 1 Podoplanin DUF2668 PF10873.3 GAM26327.1 - 0.013 15.6 2.1 0.018 15.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) DUF2613 PF11021.3 GAM26327.1 - 0.034 13.8 1.6 0.081 12.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) EF-hand_1 PF00036.27 GAM26328.1 - 1.1e-30 102.5 9.9 8.9e-05 21.5 0.0 7.7 7 0 0 7 7 7 7 EF hand EF-hand_6 PF13405.1 GAM26328.1 - 1.3e-25 86.8 6.9 0.013 15.3 0.0 7.5 7 0 0 7 7 7 7 EF-hand domain EF-hand_7 PF13499.1 GAM26328.1 - 1.5e-24 85.9 4.8 3.2e-07 30.3 0.0 5.7 4 2 0 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.1 GAM26328.1 - 9.6e-21 72.1 14.7 0.00014 21.0 0.0 7.8 8 0 0 8 8 8 7 EF hand EF-hand_8 PF13833.1 GAM26328.1 - 1.3e-15 56.7 5.6 0.047 13.3 0.0 6.9 7 0 0 7 7 7 5 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM26328.1 - 0.003 17.5 0.0 9.9 6.2 0.0 4.4 4 2 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 GAM26328.1 - 0.029 14.2 0.0 19 5.2 0.0 3.9 5 0 0 5 5 5 0 EF-hand domain Pico_P1A PF02226.11 GAM26328.1 - 0.036 13.8 0.8 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) Toprim PF01751.17 GAM26328.1 - 0.073 13.0 0.1 24 4.9 0.0 3.3 3 0 0 3 3 3 0 Toprim domain CutC PF03932.9 GAM26328.1 - 0.099 11.8 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 CutC family VCBS PF13517.1 GAM26328.1 - 0.27 11.6 7.0 25 5.3 0.2 5.5 4 2 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella IL28A PF15177.1 GAM26329.1 - 0.12 11.9 4.0 0.49 9.8 0.1 2.8 2 1 1 3 3 3 0 Interleukin-28A tRNA-synt_2b PF00587.20 GAM26330.1 - 7e-44 149.4 0.8 1e-43 148.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM26330.1 - 1e-20 73.4 0.5 2.3e-20 72.3 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 GAM26330.1 - 2.5e-09 36.8 0.0 5.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain TFIID_20kDa PF03847.8 GAM26331.1 - 2.3e-29 101.4 0.6 3.9e-29 100.7 0.4 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A SprA-related PF12118.3 GAM26331.1 - 0.00087 18.7 18.7 0.00087 18.7 13.0 2.2 2 0 0 2 2 2 2 SprA-related family SSP160 PF06933.6 GAM26331.1 - 0.0015 16.6 8.0 0.0015 16.6 5.6 3.3 2 1 1 3 3 3 1 Special lobe-specific silk protein SSP160 TFIIA PF03153.8 GAM26331.1 - 0.11 12.3 34.4 0.051 13.4 12.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 GAM26331.1 - 2.1 7.6 55.2 0.01 15.2 26.3 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 GAM26331.1 - 2.5 7.4 50.6 0.052 13.0 23.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 GAM26331.1 - 8.8 5.4 53.2 0.021 14.0 20.7 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SID-1_RNA_chan PF13965.1 GAM26331.1 - 9.1 4.3 7.1 17 3.4 4.9 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HD-ZIP_N PF04618.7 GAM26332.1 - 2.2 8.8 6.4 0.58 10.7 0.9 2.3 2 1 0 2 2 2 0 HD-ZIP protein N terminus Sec15 PF04091.7 GAM26333.1 - 1.9e-70 237.6 7.7 4.2e-70 236.5 5.3 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec5 PF15469.1 GAM26333.1 - 3.6e-09 36.6 5.2 3.6e-09 36.6 3.6 2.8 2 1 1 3 3 3 1 Exocyst complex component Sec5 COG5 PF10392.4 GAM26333.1 - 3.9e-05 23.6 0.3 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 TFIIF_alpha PF05793.7 GAM26333.1 - 1.4 7.2 31.2 0.024 13.0 16.6 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) U1snRNP70_N PF12220.3 GAM26333.1 - 1.8 8.9 17.9 5.6 7.3 0.1 3.7 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal E1-E2_ATPase PF00122.15 GAM26334.1 - 7.2e-57 192.0 3.6 1.8e-56 190.7 2.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM26334.1 - 2e-44 151.3 8.1 4e-44 150.3 3.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM26334.1 - 4.7e-29 102.3 0.0 1.1e-28 101.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM26334.1 - 7.6e-21 73.8 0.0 1.5e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM26334.1 - 6.2e-16 59.1 0.0 1.4e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM26334.1 - 8.2e-12 44.4 1.0 1e-10 40.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM26334.1 - 6.5e-05 22.6 0.0 0.0092 15.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3290 PF11694.3 GAM26334.1 - 0.0014 18.4 1.3 0.0043 16.8 0.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) EmrE PF13536.1 GAM26334.1 - 0.063 13.4 9.2 0.13 12.4 1.5 3.0 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Abhydrolase_5 PF12695.2 GAM26335.1 - 2.2e-19 69.6 0.0 3.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM26335.1 - 1.3e-12 48.0 0.0 5.1e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM26335.1 - 4.1e-12 46.1 0.2 1.1e-06 28.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 GAM26335.1 - 3.1e-06 26.8 2.3 0.00044 19.7 0.0 2.8 2 1 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 GAM26335.1 - 4.3e-05 23.0 1.0 9.3e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 GAM26335.1 - 0.00093 18.4 0.1 0.0094 15.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 GAM26335.1 - 0.0027 17.5 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase TCL1_MTCP1 PF01840.12 GAM26335.1 - 0.027 13.9 0.6 0.054 12.9 0.4 1.5 1 0 0 1 1 1 0 TCL1/MTCP1 family UIM PF02809.15 GAM26335.1 - 0.086 12.4 0.2 0.086 12.4 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif FAR1 PF03101.10 GAM26336.1 - 3e-05 24.4 0.1 3e-05 24.4 0.1 2.8 2 0 0 2 2 2 1 FAR1 DNA-binding domain Gemini_C4 PF01492.12 GAM26338.1 - 0.021 14.5 1.7 0.038 13.7 1.2 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein Mpv17_PMP22 PF04117.7 GAM26340.1 - 7.3e-16 57.5 4.2 7.3e-16 57.5 2.9 1.6 1 1 1 2 2 2 1 Mpv17 / PMP22 family Kinesin PF00225.18 GAM26341.1 - 1.1e-104 349.7 4.0 1.1e-104 349.7 2.8 2.0 3 0 0 3 3 3 1 Kinesin motor domain DUF816 PF05674.7 GAM26341.1 - 0.0072 16.0 0.3 0.02 14.6 0.2 1.7 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF816) V_ATPase_I PF01496.14 GAM26341.1 - 0.01 13.7 3.9 0.017 13.0 2.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.6 GAM26341.1 - 0.04 13.7 3.6 0.069 13.0 0.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.1 GAM26341.1 - 0.26 10.6 13.5 0.62 9.4 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Phage_GP20 PF06810.6 GAM26341.1 - 0.34 10.3 11.2 0.33 10.3 1.3 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 GAS PF13851.1 GAM26341.1 - 1 8.5 14.7 2.5 7.2 9.9 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 GAM26341.1 - 1.3 8.8 14.4 0.49 10.2 2.8 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 GAM26341.1 - 2.2 8.2 12.4 8.6 6.3 8.3 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4404 PF14357.1 GAM26341.1 - 3 8.3 8.4 0.84 10.0 0.9 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) TSC22 PF01166.13 GAM26341.1 - 3.2 7.7 11.7 0.17 11.8 2.8 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.16 GAM26341.1 - 4.8 7.2 9.1 0.54 10.2 1.2 2.8 3 1 0 3 3 3 0 bZIP transcription factor IncA PF04156.9 GAM26341.1 - 7.9 6.0 13.1 48 3.4 9.1 2.2 1 1 0 1 1 1 0 IncA protein DUF848 PF05852.6 GAM26341.1 - 9.1 6.1 13.5 1.1 9.1 3.8 2.9 2 1 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TIG PF01833.19 GAM26342.1 - 2.9e-21 75.2 63.2 6.6e-06 26.0 1.4 8.1 6 2 3 9 9 9 5 IPT/TIG domain EGF_2 PF07974.8 GAM26342.1 - 0.00029 20.9 13.0 0.00072 19.6 9.0 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM26342.1 - 0.00032 20.5 1.5 0.00082 19.2 1.1 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.22 GAM26342.1 - 0.0068 16.3 8.8 0.015 15.2 6.1 1.6 1 0 0 1 1 1 1 EGF-like domain Qn_am_d_aIII PF09099.5 GAM26342.1 - 0.031 14.5 0.2 22 5.4 0.0 4.5 5 0 0 5 5 5 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III Cyclin_N PF00134.18 GAM26343.1 - 3.6e-11 42.7 0.1 6e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 GAM26343.1 - 4.5e-11 43.3 0.1 6.5e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Cyclin GATA PF00320.22 GAM26344.1 - 6.6e-13 47.7 8.9 6.6e-13 47.7 6.1 2.1 2 0 0 2 2 2 1 GATA zinc finger DUF342 PF03961.8 GAM26344.1 - 0.061 11.7 1.7 0.1 10.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V-SNARE PF05008.10 GAM26344.1 - 0.073 13.2 5.3 0.19 11.8 3.7 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus TBPIP PF07106.8 GAM26344.1 - 0.19 11.2 12.6 0.018 14.6 4.9 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RhoGEF PF00621.15 GAM26345.1 - 4.6e-44 150.4 7.0 9.6e-44 149.4 3.9 2.3 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.26 GAM26345.1 - 4.1e-07 30.0 0.0 2.3e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain UDP-g_GGTase PF06427.6 GAM26345.1 - 0.00056 19.2 0.2 0.4 9.9 0.0 2.8 2 0 0 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase IQ PF00612.22 GAM26345.1 - 0.0016 17.8 0.1 0.0044 16.5 0.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif TRAPP PF04051.11 GAM26346.1 - 7.8e-39 132.6 0.1 9.1e-39 132.4 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DCX PF03607.12 GAM26347.1 - 1.8e-32 110.6 0.3 1.5e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 Doublecortin PRCC PF10253.4 GAM26347.1 - 0.031 14.9 1.2 0.05 14.2 0.8 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mucin PF01456.12 GAM26347.1 - 0.077 12.7 20.9 0.12 12.1 14.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.6 GAM26347.1 - 1.3 8.7 14.6 2.1 8.1 10.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Med3 PF11593.3 GAM26347.1 - 1.8 7.7 11.2 2.4 7.3 7.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Dicty_REP PF05086.7 GAM26347.1 - 4.8 4.7 6.8 6.4 4.4 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.2 GAM26348.1 - 5.9e-07 29.1 0.0 1.8e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM26348.1 - 0.00067 19.2 0.1 0.0026 17.3 0.0 2.1 1 1 0 1 1 1 1 F-box domain BTK PF00779.14 GAM26348.1 - 0.0019 17.7 1.7 0.004 16.7 1.2 1.5 1 0 0 1 1 1 1 BTK motif Elongin_A PF06881.6 GAM26348.1 - 0.0041 17.4 0.3 0.0064 16.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CHORD PF04968.7 GAM26348.1 - 1.7 8.9 5.3 2.7 8.2 2.5 2.3 2 1 0 2 2 2 0 CHORD Nramp PF01566.13 GAM26349.1 - 2.9e-123 411.2 16.0 2.9e-123 411.2 11.1 1.8 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF2207 PF09972.4 GAM26349.1 - 1.8 7.0 8.1 0.45 9.0 2.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 GAM26350.1 - 8.6e-58 190.2 29.3 8.9e-08 31.7 0.3 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat DENN PF02141.16 GAM26350.1 - 5.3e-50 169.7 12.0 8.7e-50 169.0 6.9 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 GAM26350.1 - 5.1e-19 67.9 0.3 1.4e-18 66.5 0.2 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 GAM26350.1 - 7.4e-14 51.5 5.8 2e-13 50.2 3.3 2.4 2 0 0 2 2 2 1 dDENN domain C2 PF00168.25 GAM26350.1 - 1.8e-09 37.2 1.0 5.3e-09 35.7 0.3 2.1 2 0 0 2 2 2 1 C2 domain SBF2 PF12335.3 GAM26350.1 - 8.5e-05 21.9 0.9 8.5e-05 21.9 0.6 2.6 2 0 0 2 2 2 1 Myotubularin protein Nup160 PF11715.3 GAM26350.1 - 0.00012 20.3 35.0 0.018 13.1 0.0 7.8 5 2 3 8 8 8 3 Nucleoporin Nup120/160 CAF-1_p150 PF11600.3 GAM26350.1 - 0.0028 17.0 18.7 0.0028 17.0 13.0 3.7 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal KH_1 PF00013.24 GAM26350.1 - 0.13 11.9 0.9 0.38 10.4 0.6 1.8 1 0 0 1 1 1 0 KH domain Voltage_CLC PF00654.15 GAM26351.1 - 1.5e-87 293.8 21.4 1.5e-87 293.8 14.8 1.9 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 GAM26351.1 - 6.9e-12 44.9 5.3 1.2e-05 25.0 0.0 3.1 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.4 GAM26351.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DUF2951 PF11166.3 GAM26351.1 - 1.6 8.6 4.4 0.68 9.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) GATA PF00320.22 GAM26352.1 - 1e-14 53.5 2.8 1e-14 53.5 2.0 2.0 2 0 0 2 2 2 1 GATA zinc finger Syntaxin-6_N PF09177.6 GAM26352.1 - 0.022 15.1 0.2 0.051 13.9 0.1 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF3439 PF11921.3 GAM26353.1 - 0.1 12.3 11.7 0.072 12.8 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PYRIN PF02758.11 GAM26355.1 - 0.072 12.7 2.0 0.39 10.4 0.1 2.7 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain DUF4485 PF14846.1 GAM26355.1 - 0.37 10.5 2.6 0.39 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) BAR PF03114.13 GAM26355.1 - 3.1 7.2 7.0 4.5 6.7 4.9 1.3 1 1 0 1 1 1 0 BAR domain MIP-T3 PF10243.4 GAM26356.1 - 0.0083 14.6 23.6 0.0079 14.7 16.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CKAP2_C PF15297.1 GAM26356.1 - 0.16 10.7 18.9 0.19 10.5 13.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Adaptin_binding PF10199.4 GAM26356.1 - 0.2 11.9 19.6 0.31 11.3 13.6 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 GAM26356.1 - 0.24 9.4 23.2 0.26 9.2 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 GAM26356.1 - 1 7.6 32.8 1.3 7.2 22.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.11 GAM26356.1 - 1.8 8.3 6.1 1.7 8.4 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TEX19 PF15553.1 GAM26356.1 - 1.9 8.3 8.1 2.4 7.9 5.6 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Nop14 PF04147.7 GAM26356.1 - 3.7 5.3 29.2 4.3 5.1 20.3 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 GAM26356.1 - 4.6 7.2 29.0 1.2 9.1 18.2 1.4 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.2 GAM26356.1 - 5 7.2 24.3 8.1 6.5 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.7 GAM26356.1 - 6.3 6.6 22.6 8.1 6.2 15.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.5 GAM26356.1 - 8.4 4.6 5.6 8.4 4.6 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.1 GAM26356.1 - 8.6 4.7 12.1 11 4.4 8.4 1.2 1 0 0 1 1 1 0 Raftlin DUF1510 PF07423.6 GAM26356.1 - 9.9 5.4 33.5 15 4.9 23.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FNIP PF05725.7 GAM26357.1 - 2.1e-06 27.5 11.6 0.049 13.5 0.0 7.6 7 2 1 8 8 8 5 FNIP Repeat DUF4537 PF15057.1 GAM26358.1 - 0.0068 16.1 3.3 0.032 14.0 0.2 2.8 2 1 0 3 3 3 1 Domain of unknown function (DUF4537) Daxx PF03344.10 GAM26358.1 - 1.6 7.1 11.5 2 6.8 8.0 1.1 1 0 0 1 1 1 0 Daxx Family Med3 PF11593.3 GAM26359.1 - 0.82 8.8 18.2 1.4 8.0 12.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_S21 PF00716.12 GAM26359.1 - 3.6 6.8 10.1 4.6 6.4 7.0 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Phage_integrase PF00589.17 GAM26361.1 - 7.7e-12 45.2 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 GAM26361.1 - 5.1e-05 23.3 0.2 0.00012 22.1 0.1 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 GAM26361.1 - 0.00011 22.4 1.0 0.00026 21.2 0.3 1.9 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain PyrI PF01948.13 GAM26362.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Retrotrans_gag PF03732.12 GAM26363.1 - 1.6e-05 24.8 0.1 2.7e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 GAM26363.1 - 0.062 12.8 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-BED PF02892.10 GAM26364.1 - 0.16 11.7 4.1 0.65 9.7 1.3 2.6 2 0 0 2 2 2 0 BED zinc finger RVP PF00077.15 GAM26365.1 - 2.9e-06 27.1 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 GAM26365.1 - 0.00044 20.6 0.0 0.0008 19.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 GAM26365.1 - 0.0038 17.0 0.6 0.0095 15.8 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 GAM26365.1 - 0.019 14.6 0.8 0.05 13.2 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.5 GAM26365.1 - 0.037 13.5 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease vMSA PF00695.14 GAM26365.1 - 0.18 10.9 2.0 0.23 10.6 1.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus rve PF00665.21 GAM26366.1 - 1.2e-13 51.2 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF4537 PF15057.1 GAM26368.1 - 0.00074 19.2 0.2 0.0033 17.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) HMG_CoA_synt_C PF08540.5 GAM26369.1 - 5.9e-98 327.8 4.0 7.4e-98 327.4 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 GAM26369.1 - 1.6e-88 294.7 0.5 2.3e-88 294.2 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Myb_Cef PF11831.3 GAM26369.1 - 0.051 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component ACP_syn_III PF08545.5 GAM26369.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SYF2 PF08231.7 GAM26370.1 - 8.4e-23 81.1 12.6 8.4e-23 81.1 8.8 2.5 1 1 1 2 2 2 1 SYF2 splicing factor TUDOR PF00567.19 GAM26370.1 - 0.058 13.2 1.1 1.3 8.8 0.0 3.0 2 1 0 3 3 3 0 Tudor domain DUF236 PF03057.9 GAM26370.1 - 0.55 10.1 5.0 4.8 7.1 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function HEAT_2 PF13646.1 GAM26371.1 - 2.5e-15 56.5 0.1 0.00092 19.4 0.0 4.7 2 2 2 4 4 4 4 HEAT repeats Arm PF00514.18 GAM26371.1 - 1.9e-14 52.8 11.4 0.0071 16.1 0.0 7.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAM26371.1 - 0.0019 18.1 5.7 1.6 9.0 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat UNC45-central PF11701.3 GAM26371.1 - 0.0019 17.8 11.3 0.019 14.6 1.7 4.0 1 1 2 4 4 4 1 Myosin-binding striated muscle assembly central Xpo1 PF08389.7 GAM26371.1 - 0.0038 17.1 1.2 0.0038 17.1 0.8 3.6 2 1 0 3 3 3 1 Exportin 1-like protein DUF2326 PF10088.4 GAM26371.1 - 0.02 14.5 0.5 0.14 11.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2326) RasGEF_N_2 PF14663.1 GAM26371.1 - 0.9 9.5 4.2 16 5.4 0.1 4.0 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pkinase_Tyr PF07714.12 GAM26372.1 - 2.1e-34 118.8 0.1 5.1e-34 117.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26372.1 - 5.9e-33 114.1 0.0 1.4e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 GAM26372.1 - 0.0016 17.4 0.3 0.0053 15.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF2443 PF10398.4 GAM26372.1 - 0.13 12.1 1.1 0.94 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) CTNNBL PF08216.6 GAM26372.1 - 0.6 9.7 5.2 12 5.5 0.1 2.7 1 1 1 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear SIS PF01380.17 GAM26374.1 - 1.4e-36 124.9 1.8 6.1e-21 74.3 0.1 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 GAM26374.1 - 3.8e-24 85.1 0.0 8.7e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 GAM26374.1 - 2.3e-19 69.3 0.0 5.3e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 GAM26374.1 - 8.6e-17 60.8 0.0 3.2e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 GAM26374.1 - 0.0012 17.5 0.3 0.0028 16.4 0.1 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Prenylcys_lyase PF07156.9 GAM26375.1 - 2.1e-68 230.8 1.8 2.5e-68 230.6 1.2 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 GAM26375.1 - 1.5e-10 40.9 0.2 3.3e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAM26375.1 - 2.4e-07 30.1 0.0 3.2e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAM26375.1 - 2.4e-05 23.3 0.2 3.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM26375.1 - 0.00099 19.0 0.4 0.024 14.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 GAM26375.1 - 0.0055 15.3 0.1 0.011 14.3 0.1 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM26375.1 - 0.0062 16.3 0.2 0.022 14.5 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 GAM26375.1 - 0.011 15.8 0.0 0.062 13.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_19 PF14559.1 GAM26377.1 - 0.00039 20.6 0.3 4.3 7.7 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26377.1 - 0.00065 19.4 0.5 0.024 14.5 0.0 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26377.1 - 0.017 15.7 0.5 20 6.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Nuc-transf PF10127.4 GAM26378.1 - 1.5e-23 83.4 4.3 1.1e-12 47.8 2.0 3.7 2 2 0 2 2 2 2 Predicted nucleotidyltransferase Baculo_LEF-11 PF06385.7 GAM26378.1 - 0.011 15.7 0.9 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 Baculovirus LEF-11 protein MFS_1 PF07690.11 GAM26379.1 - 3.4e-24 85.2 18.6 3.4e-24 85.2 12.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 GAM26379.1 - 0.0022 16.9 0.0 0.0052 15.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M50 TFIIA PF03153.8 GAM26380.1 - 1.4e-35 123.9 24.5 1.3e-28 100.9 13.1 2.6 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit FGF-BP1 PF06473.7 GAM26380.1 - 0.13 11.8 2.5 0.25 10.9 1.8 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Macoilin PF09726.4 GAM26380.1 - 0.54 8.4 3.6 0.64 8.2 2.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 GAM26380.1 - 1.3 9.0 9.4 0.53 10.3 4.7 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM110_C PF14160.1 GAM26380.1 - 3.2 8.7 5.7 2.9 8.8 1.0 2.3 2 1 0 2 2 2 0 Centrosome-associated C terminus Syntaxin-6_N PF09177.6 GAM26381.1 - 5.3e-23 81.2 1.4 5.3e-23 81.2 1.0 2.5 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 GAM26381.1 - 1.8e-11 43.5 0.7 1.8e-11 43.5 0.5 2.7 3 0 0 3 3 3 1 SNARE domain Plasmid_stab_B PF10784.4 GAM26381.1 - 0.082 12.5 0.7 4.5 6.9 0.0 2.6 1 1 1 2 2 2 0 Plasmid stability protein TPK_catalytic PF04263.11 GAM26381.1 - 0.086 12.4 0.4 0.9 9.1 0.0 2.4 2 1 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DUF4477 PF14780.1 GAM26381.1 - 0.1 11.9 5.2 0.052 12.9 0.9 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4477) DUF3095 PF11294.3 GAM26381.1 - 1.3 7.9 5.5 2.1 7.2 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3095) Mga PF05043.8 GAM26381.1 - 1.6 9.0 7.1 7.7 6.8 0.7 3.0 2 1 1 3 3 3 0 Mga helix-turn-helix domain KLRAQ PF10205.4 GAM26381.1 - 1.7 8.6 11.2 0.11 12.4 2.8 2.4 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein Phage_Gp23 PF10669.4 GAM26381.1 - 5.2 7.2 11.3 10 6.2 7.2 2.2 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CRAL_TRIO_2 PF13716.1 GAM26382.1 - 2.3e-20 72.9 1.1 2.3e-20 72.9 0.8 2.0 2 1 0 2 2 2 1 Divergent CRAL/TRIO domain Macro PF01661.16 GAM26382.1 - 8.7e-20 70.7 0.7 5.1e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.15 GAM26382.1 - 7.7e-07 28.7 0.4 2.3e-06 27.1 0.3 1.7 1 1 0 1 1 1 1 CRAL/TRIO domain EF-hand_7 PF13499.1 GAM26384.1 - 4.1e-14 52.4 4.2 5.8e-09 35.9 0.5 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAM26384.1 - 2e-12 45.4 7.4 0.0012 17.9 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 GAM26384.1 - 1.6e-10 39.9 6.0 0.015 15.1 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAM26384.1 - 5.2e-07 29.1 5.4 0.00042 19.8 0.1 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM26384.1 - 5.7e-07 28.5 10.5 0.079 12.3 0.0 5.2 5 1 0 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.4 GAM26384.1 - 5e-05 23.3 1.3 0.0041 17.1 0.1 2.8 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM26384.1 - 0.06 13.0 0.4 3.1 7.5 0.0 3.3 4 0 0 4 4 4 0 EF hand Lon_C PF05362.8 GAM26385.1 - 3.7e-72 241.9 0.0 7e-72 241.0 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 GAM26385.1 - 7.8e-23 81.1 0.0 4.3e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 GAM26385.1 - 1.4e-08 34.6 2.9 6e-08 32.6 2.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 GAM26385.1 - 3.2e-08 33.1 0.3 1.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 GAM26385.1 - 5.5e-07 29.6 0.6 2.5e-06 27.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 GAM26385.1 - 6.6e-07 28.6 0.1 4.8e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 GAM26385.1 - 6.2e-06 25.1 1.2 0.0017 17.1 0.2 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 GAM26385.1 - 6.4e-06 25.9 0.0 2.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM26385.1 - 0.00012 22.0 0.0 0.00035 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 GAM26385.1 - 0.00014 22.6 0.0 0.00042 21.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM26385.1 - 0.00025 21.1 0.4 0.016 15.3 0.3 3.0 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 GAM26385.1 - 0.00047 18.9 0.0 0.00099 17.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.1 GAM26385.1 - 0.0011 19.2 0.3 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM26385.1 - 0.0059 16.4 0.4 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 GAM26385.1 - 0.012 15.9 0.0 0.012 15.9 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_19 PF13245.1 GAM26385.1 - 0.02 14.6 0.5 0.02 14.6 0.4 1.9 2 0 0 2 2 1 0 Part of AAA domain MCM PF00493.18 GAM26385.1 - 0.021 13.6 0.3 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 MCM2/3/5 family Mg_chelatase PF01078.16 GAM26385.1 - 0.022 13.9 0.1 0.057 12.5 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAM26385.1 - 0.023 14.5 0.1 0.068 13.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM26385.1 - 0.033 13.8 0.2 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 GAM26385.1 - 0.039 14.1 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 GAM26385.1 - 0.042 13.7 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Shikimate kinase Zeta_toxin PF06414.7 GAM26385.1 - 0.054 12.5 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 GAM26385.1 - 0.062 12.7 0.1 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 GAM26385.1 - 0.073 12.4 0.2 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 GAM26385.1 - 0.084 12.8 3.6 1.9 8.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 GAM26385.1 - 0.086 12.4 0.4 2.8 7.5 0.0 2.9 3 0 0 3 3 3 0 NACHT domain PG_binding_1 PF01471.13 GAM26385.1 - 0.089 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain AAA_30 PF13604.1 GAM26385.1 - 0.089 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bap31 PF05529.7 GAM26385.1 - 0.48 9.8 5.9 1.1 8.6 4.1 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1798 PF08807.5 GAM26386.1 - 0.0032 17.1 0.6 0.0042 16.7 0.4 1.1 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) DUF2454 PF10521.4 GAM26386.1 - 0.019 14.0 0.3 0.02 13.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) LysE PF01810.13 GAM26386.1 - 0.02 14.1 0.2 0.026 13.8 0.2 1.1 1 0 0 1 1 1 0 LysE type translocator MRF_C1 PF13887.1 GAM26386.1 - 0.035 13.1 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 E_Pc_C PF06752.7 GAM26386.1 - 0.5 9.8 3.7 0.6 9.5 2.6 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Ndc1_Nup PF09531.5 GAM26387.1 - 1.8e-06 26.6 0.2 1.8e-06 26.6 0.1 3.8 2 1 2 4 4 4 3 Nucleoporin protein Ndc1-Nup DAGK_acc PF00609.14 GAM26388.1 - 2.4e-36 125.2 0.1 1.6e-28 99.8 0.0 2.4 1 1 1 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 GAM26388.1 - 6.2e-27 93.5 0.0 9.6e-27 92.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 GAM26388.1 - 1.2e-26 92.2 47.9 4.4e-11 42.3 8.8 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_32 PF13679.1 GAM26389.1 - 1.3e-24 86.4 2.5 3.6e-24 85.0 1.7 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM26389.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM26389.1 - 0.00067 19.2 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAM26389.1 - 0.0012 19.3 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM26389.1 - 0.0031 17.9 0.0 0.0086 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM26389.1 - 0.0031 17.2 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM26389.1 - 0.0057 16.0 0.7 0.032 13.6 0.1 2.3 2 1 1 3 3 3 1 Methyltransferase small domain RrnaAD PF00398.15 GAM26389.1 - 0.0076 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 GAM26389.1 - 0.0085 16.5 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM26389.1 - 0.064 13.6 0.0 0.24 11.7 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain RAB3GAP2_N PF14655.1 GAM26391.1 - 0.024 13.6 0.4 0.062 12.2 0.2 1.6 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CRT-like PF08627.5 GAM26393.1 - 9.6e-40 135.5 0.2 9.6e-40 135.5 0.1 2.3 3 0 0 3 3 3 1 CRT-like DUF914 PF06027.7 GAM26393.1 - 8.6e-12 44.5 10.2 2.8e-10 39.5 1.8 2.4 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 GAM26393.1 - 0.0019 18.3 15.6 0.14 12.4 2.9 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 GAM26393.1 - 0.0067 16.0 19.2 0.034 13.7 3.4 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family RNA_helicase PF00910.17 GAM26394.1 - 0.035 14.2 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FNIP PF05725.7 GAM26395.1 - 1.6e-119 389.6 36.2 1.5e-12 47.2 0.0 12.3 9 2 3 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 GAM26395.1 - 2e-07 30.8 13.5 0.53 10.2 0.0 9.8 8 4 4 12 12 12 3 Protein of unknown function (DUF1769) Histone PF00125.19 GAM26396.1 - 1.4e-13 50.7 0.2 1.8e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM26396.1 - 4.3e-05 23.5 0.2 5.4e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 GAM26396.1 - 4.6e-05 23.2 0.0 6.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 GAM26396.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 GAM26396.1 - 0.00081 19.0 0.1 0.0031 17.2 0.0 1.8 1 1 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 GAM26396.1 - 0.0076 15.5 0.0 0.008 15.4 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 GAM26396.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 GAM26396.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GTP_EFTU PF00009.22 GAM26397.1 - 5.9e-58 195.4 0.0 8.3e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM26397.1 - 4.9e-33 113.2 0.1 1.4e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM26397.1 - 3.4e-17 62.3 0.2 1e-16 60.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM26397.1 - 0.00017 21.5 0.1 0.00058 19.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 GAM26397.1 - 0.00029 20.4 0.0 0.00072 19.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 GAM26397.1 - 0.036 14.5 0.2 0.29 11.6 0.2 2.2 1 1 0 1 1 1 0 Miro-like protein HATPase_c_3 PF13589.1 GAM26398.1 - 1.1e-21 76.8 0.5 3.6e-21 75.2 0.4 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM26398.1 - 0.00016 21.3 0.1 0.00052 19.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carbpep_Y_N PF05388.6 GAM26399.1 - 0.038 14.1 0.0 0.078 13.1 0.0 1.6 1 1 0 1 1 1 0 Carboxypeptidase Y pro-peptide ATP-synt_Eps PF04627.8 GAM26400.1 - 5.4e-17 61.0 0.0 6.6e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF1620 PF07774.8 GAM26401.1 - 4.1e-49 166.7 1.5 4.1e-49 166.7 1.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1620) PP2C PF00481.16 GAM26402.1 - 2.7e-60 203.9 0.2 6.6e-60 202.6 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_6 PF13516.1 GAM26402.1 - 2.2e-08 33.3 8.3 0.11 12.5 0.0 6.7 6 0 0 6 6 6 2 Leucine Rich repeat PP2C_2 PF13672.1 GAM26402.1 - 2.7e-07 30.2 0.1 3.3e-06 26.6 0.0 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 GAM26402.1 - 0.1 12.2 15.5 0.15 11.6 0.5 3.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM26402.1 - 0.36 10.6 7.9 0.72 9.6 0.4 3.6 3 1 0 3 3 3 0 Leucine rich repeat YjbE PF11106.3 GAM26402.1 - 2.1 8.3 7.2 4.5 7.3 5.0 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE LRR_7 PF13504.1 GAM26402.1 - 3.1 8.3 7.9 1.4e+02 3.3 0.6 5.5 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 GAM26402.1 - 5.4 7.4 10.8 23 5.5 0.1 4.9 4 2 0 4 4 4 0 Leucine Rich Repeat DUF4200 PF13863.1 GAM26403.1 - 0.0024 17.8 2.0 0.0024 17.8 1.4 4.9 5 1 0 5 5 5 1 Domain of unknown function (DUF4200) DNA_ligase_A_C PF04679.10 GAM26403.1 - 0.078 13.3 0.0 0.36 11.2 0.0 2.1 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region PspB PF06667.7 GAM26403.1 - 0.14 12.1 1.9 0.46 10.4 0.1 2.7 2 0 0 2 2 2 0 Phage shock protein B Nefa_Nip30_N PF10187.4 GAM26404.1 - 3.9e-16 59.0 14.6 3.9e-16 59.0 10.1 2.5 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2220 PF09983.4 GAM26404.1 - 1.7 7.7 6.5 3.8 6.6 4.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) API5 PF05918.6 GAM26405.1 - 6.4e-53 180.1 10.8 7e-52 176.6 7.5 2.2 1 1 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) IFN-gamma PF00714.12 GAM26405.1 - 0.0083 15.9 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Interferon gamma HEAT_2 PF13646.1 GAM26405.1 - 0.02 15.1 0.0 0.065 13.5 0.0 1.9 1 1 1 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 GAM26405.1 - 0.16 12.4 0.1 6 7.4 0.0 2.5 1 1 1 2 2 2 0 HEAT-like repeat Kelch_6 PF13964.1 GAM26406.1 - 1.8e-27 94.3 14.5 3.6e-09 36.3 0.0 6.7 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.1 GAM26406.1 - 1.3e-26 92.0 11.9 7.5e-06 25.7 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 GAM26406.1 - 4.9e-26 90.2 22.8 5.1e-08 32.5 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM26406.1 - 1.6e-25 88.6 14.9 2.3e-10 40.3 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM26406.1 - 1.6e-23 81.9 17.1 1.4e-06 27.6 0.1 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM26406.1 - 2.2e-22 77.8 10.6 1.2e-05 24.8 0.2 6.7 6 1 0 6 6 6 5 Kelch motif EGF_CA PF07645.10 GAM26407.1 - 1.7e-09 37.5 5.8 1.7e-09 37.5 4.0 4.8 4 1 0 4 4 3 1 Calcium-binding EGF domain hEGF PF12661.2 GAM26407.1 - 5.6e-07 29.2 21.6 0.001 19.0 1.1 4.0 3 1 0 3 3 3 2 Human growth factor-like EGF EGF PF00008.22 GAM26407.1 - 3.2e-05 23.7 37.8 0.017 15.0 7.7 4.0 3 0 0 3 3 3 3 EGF-like domain EGF_3 PF12947.2 GAM26407.1 - 0.00019 21.3 7.6 0.00019 21.3 5.2 4.2 4 1 0 4 4 3 1 EGF domain TIG PF01833.19 GAM26407.1 - 0.00021 21.2 6.3 0.00021 21.2 4.4 3.7 2 2 1 3 3 3 1 IPT/TIG domain FXa_inhibition PF14670.1 GAM26407.1 - 0.0053 16.8 9.9 0.0053 16.8 6.9 3.9 3 0 0 3 3 3 1 Coagulation Factor Xa inhibitory site DUF1191 PF06697.7 GAM26407.1 - 0.0079 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EB PF01683.13 GAM26407.1 - 0.013 15.5 4.2 0.013 15.5 2.9 3.7 2 1 0 2 2 1 0 EB module EGF_2 PF07974.8 GAM26407.1 - 0.024 14.7 13.2 0.024 14.7 9.2 3.7 3 0 0 3 3 3 0 EGF-like domain cEGF PF12662.2 GAM26407.1 - 0.18 11.4 25.9 0.071 12.7 0.5 4.3 4 0 0 4 4 4 0 Complement Clr-like EGF-like Laminin_EGF PF00053.19 GAM26407.1 - 5.6 6.9 33.4 1.7 8.6 4.9 3.5 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) DUF3278 PF11683.3 GAM26408.1 - 9.4 6.2 15.1 5.5 6.9 1.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) PRP1_N PF06424.7 GAM26409.1 - 1e-41 142.4 7.7 2.8e-41 140.9 5.4 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 GAM26409.1 - 7.9e-34 113.0 7.3 0.0053 17.2 0.0 13.2 4 3 10 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26409.1 - 5e-23 81.2 0.9 0.0091 16.3 0.0 8.0 6 2 1 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26409.1 - 3.8e-18 65.6 0.0 0.0062 17.1 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 GAM26409.1 - 5.1e-11 42.8 3.3 1.5e-06 28.1 0.0 4.5 3 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 GAM26409.1 - 5e-10 38.8 0.3 0.22 11.1 0.0 7.2 5 1 2 7 7 7 2 TPR repeat TPR_2 PF07719.12 GAM26409.1 - 1.4e-06 27.7 0.1 0.8 9.7 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26409.1 - 6.7e-05 22.7 0.1 57 4.2 0.0 7.7 9 1 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26409.1 - 0.00019 21.6 4.5 3.7 8.2 0.0 7.2 9 0 0 9 9 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26409.1 - 0.0003 20.6 1.2 0.17 11.8 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26409.1 - 0.001 18.6 0.8 6.7 6.7 0.0 6.5 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF1570 PF07607.6 GAM26409.1 - 0.0047 16.9 0.2 0.029 14.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1570) TPR_7 PF13176.1 GAM26409.1 - 0.0063 16.2 0.1 2.6 8.0 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM26409.1 - 0.025 14.1 0.0 2.7 7.7 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Cutinase PF01083.17 GAM26409.1 - 0.12 12.1 0.4 4.8 6.8 0.0 3.7 5 1 1 6 6 5 0 Cutinase Beach PF02138.13 GAM26410.1 - 9.8e-59 198.9 0.0 3.5e-58 197.2 0.0 2.0 1 0 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.20 GAM26410.1 - 3.4e-16 59.1 0.0 5.4e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.27 GAM26410.1 - 3.3e-11 42.5 16.2 1.6e-08 34.0 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat Kinase-like PF14531.1 GAM26410.1 - 0.0013 17.7 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 GAM26410.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Nop PF01798.13 GAM26411.1 - 1.9e-55 186.2 0.2 1.9e-55 186.2 0.1 2.2 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 GAM26411.1 - 2.7e-23 81.5 0.0 4.9e-23 80.6 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 GAM26411.1 - 2e-21 75.9 0.2 2e-21 75.9 0.1 3.6 3 2 2 5 5 5 1 NOP5NT (NUC127) domain Coiled PF05710.7 GAM26412.1 - 0.18 12.3 6.2 0.28 11.6 4.3 1.4 1 1 0 1 1 1 0 Coiled coil Peptidase_S9 PF00326.16 GAM26412.1 - 0.24 10.5 0.7 0.28 10.3 0.5 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Coiled PF05710.7 GAM26413.1 - 0.18 12.3 6.2 0.28 11.6 4.3 1.4 1 1 0 1 1 1 0 Coiled coil Peptidase_S9 PF00326.16 GAM26413.1 - 0.24 10.5 0.7 0.28 10.3 0.5 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family PemK PF02452.12 GAM26414.1 - 0.00085 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 PemK-like protein Rota_NSP4 PF01452.11 GAM26414.1 - 0.0017 17.7 2.0 0.0017 17.7 1.4 1.6 2 0 0 2 2 2 1 Rotavirus non structural protein Ependymin PF00811.13 GAM26415.1 - 0.0003 20.5 0.7 0.00048 19.8 0.1 1.6 2 0 0 2 2 2 1 Ependymin Chitin_bind_3 PF03067.10 GAM26416.1 - 4.9e-05 23.6 0.5 7.6e-05 23.0 0.3 1.5 1 1 0 1 1 1 1 Chitin binding domain Gar1 PF04410.9 GAM26417.1 - 1e-27 96.4 2.5 8.5e-17 61.0 0.0 3.5 3 2 1 4 4 4 2 Gar1/Naf1 RNA binding region DUF3123 PF11321.3 GAM26417.1 - 0.063 13.5 1.0 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) EB1 PF03271.12 GAM26419.1 - 4.7e-11 42.5 1.7 4.7e-11 42.5 1.2 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 GAM26419.1 - 7.9e-10 38.7 0.7 1.6e-09 37.7 0.2 1.8 2 0 0 2 2 2 1 Calponin homology (CH) domain TFIIA PF03153.8 GAM26419.1 - 0.00035 20.5 10.2 0.00057 19.8 7.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.4 GAM26419.1 - 0.85 8.1 12.6 1.6 7.3 8.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein EF-hand_1 PF00036.27 GAM26420.1 - 9.9e-14 49.5 4.9 6.8e-07 28.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 GAM26420.1 - 1.5e-12 47.4 0.1 4.8e-12 45.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM26420.1 - 9e-12 43.8 0.4 5.3e-06 25.8 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 GAM26420.1 - 1.2e-10 40.7 0.4 2e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 GAM26420.1 - 4.3e-09 35.2 0.5 1.7e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 EF hand WWE PF02825.15 GAM26420.1 - 4.5e-09 35.5 2.6 1.2e-08 34.2 1.8 1.8 1 0 0 1 1 1 1 WWE domain SPARC_Ca_bdg PF10591.4 GAM26420.1 - 0.00013 21.9 0.2 0.00096 19.1 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 GAM26420.1 - 0.0016 18.3 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain p450 PF00067.17 GAM26421.1 - 1.5e-89 300.6 0.3 1.7e-89 300.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 YhhN PF07947.9 GAM26422.1 - 1.8e-12 47.0 25.9 1.7e-07 30.8 2.1 3.0 2 1 1 3 3 3 2 YhhN-like protein Rifin_STEVOR PF02009.11 GAM26422.1 - 0.0038 16.9 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family Macoilin PF09726.4 GAM26422.1 - 0.0046 15.3 2.1 0.0065 14.8 1.4 1.4 1 1 0 1 1 1 1 Transmembrane protein DUF912 PF06024.7 GAM26422.1 - 0.0052 16.8 2.0 0.0052 16.8 1.4 4.3 2 1 1 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) AATase PF07247.7 GAM26423.1 - 9.4e-08 31.0 0.9 0.0041 15.7 0.1 2.2 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 GAM26423.1 - 0.0016 17.3 0.0 0.0036 16.2 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Got1 PF04178.7 GAM26424.1 - 2.1e-25 89.0 23.2 2.6e-25 88.8 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family YwiC PF14256.1 GAM26424.1 - 0.3 11.1 10.1 0.46 10.5 7.0 1.4 1 1 0 1 1 1 0 YwiC-like protein DUF3040 PF11239.3 GAM26424.1 - 1.2 9.2 5.9 6.3 6.9 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) S-AdoMet_synt_C PF02773.11 GAM26427.1 - 5.8e-71 236.6 0.1 9.2e-71 235.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 GAM26427.1 - 5.4e-49 165.1 0.0 1.2e-48 163.9 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 GAM26427.1 - 2.6e-44 149.5 0.8 5.3e-44 148.5 0.6 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 GAM26427.1 - 0.0073 15.4 0.0 0.22 10.6 0.0 2.1 2 0 0 2 2 2 1 Amidinotransferase MSA_2 PF00985.12 GAM26427.1 - 0.093 12.8 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family CLN3 PF02487.12 GAM26428.1 - 4.8e-54 183.6 14.8 7e-54 183.1 5.7 2.2 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 GAM26428.1 - 2.1e-09 36.5 12.2 3.8e-09 35.7 8.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 GAM26429.1 - 2.8e-38 130.1 4.3 2.7e-17 62.8 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26429.1 - 1.4e-36 122.5 10.9 2.5e-06 27.0 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 GAM26429.1 - 2.4e-29 101.1 9.5 5e-08 33.2 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26429.1 - 6.2e-29 99.3 17.2 1.4e-07 31.5 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26429.1 - 4.6e-28 94.4 4.5 0.00018 21.4 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat PseudoU_synth_2 PF00849.17 GAM26430.1 - 2.3e-17 63.3 0.0 1.2e-16 60.9 0.0 2.1 2 1 0 2 2 2 1 RNA pseudouridylate synthase Ank_2 PF12796.2 GAM26431.1 - 6.8e-13 48.7 6.7 0.029 14.6 0.0 6.8 6 3 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26431.1 - 4.8e-06 26.9 6.1 4.3 7.9 0.2 7.4 8 1 1 9 9 9 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26431.1 - 0.0027 17.9 3.7 46 4.4 0.1 7.6 8 1 1 9 9 9 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26431.1 - 0.0094 16.1 8.6 46 4.6 0.2 8.2 9 0 0 9 9 9 0 Ankyrin repeat Clathrin PF00637.15 GAM26431.1 - 0.012 15.1 0.2 0.48 10.0 0.0 3.3 3 0 0 3 3 3 0 Region in Clathrin and VPS B12-binding_2 PF02607.12 GAM26431.1 - 0.015 15.3 0.5 1.8 8.6 0.0 3.9 4 0 0 4 4 4 0 B12 binding domain Spo0A_C PF08769.6 GAM26431.1 - 0.045 13.6 0.0 7.4 6.4 0.0 3.4 2 1 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal Ank PF00023.25 GAM26431.1 - 0.055 13.3 10.6 12 5.9 0.6 6.4 7 0 0 7 7 7 0 Ankyrin repeat PPR_3 PF13812.1 GAM26431.1 - 0.064 13.5 0.1 85 3.8 0.0 4.9 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Endotoxin_N PF03945.9 GAM26432.1 - 2.2e-14 53.3 0.3 5.2e-14 52.1 0.1 1.6 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain DNA_ligase_OB_2 PF14743.1 GAM26432.1 - 0.052 13.2 0.2 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 DNA ligase OB-like domain HAP2-GCS1 PF10699.4 GAM26433.1 - 1.1e-11 44.5 0.2 1.8e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Male gamete fusion factor Ank_2 PF12796.2 GAM26434.1 - 0.00014 22.1 3.7 0.13 12.6 0.1 4.6 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26434.1 - 0.00066 20.1 1.8 34 5.1 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeats (many copies) Tn7_Tnp_TnsA_C PF08721.6 GAM26434.1 - 0.017 15.1 0.2 0.28 11.2 0.0 3.0 3 0 0 3 3 3 0 TnsA endonuclease C terminal Ank_3 PF13606.1 GAM26434.1 - 6.5 7.3 11.1 2.5 8.6 0.0 5.4 7 0 0 7 7 7 0 Ankyrin repeat Ank_2 PF12796.2 GAM26435.1 - 7.7e-07 29.3 0.3 0.0011 19.2 0.0 3.7 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26435.1 - 3.8e-05 23.5 1.1 1.9 8.9 0.0 5.7 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 GAM26435.1 - 0.00085 19.4 0.1 3.6 7.9 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM26435.1 - 0.0032 17.1 0.6 10 6.1 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAM26435.1 - 0.011 16.2 0.4 5.8 7.5 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) GSHPx PF00255.14 GAM26436.1 - 7.9e-14 50.9 0.2 1e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Cullin PF00888.17 GAM26437.1 - 2.9e-60 204.4 10.7 2.9e-60 204.4 7.4 3.1 2 1 1 3 3 3 1 Cullin family APC2 PF08672.6 GAM26437.1 - 8.8e-19 67.5 0.3 2.8e-18 65.9 0.2 2.0 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Kinesin PF00225.18 GAM26438.1 - 8.6e-112 373.1 0.9 8.6e-112 373.1 0.6 2.0 2 0 0 2 2 2 1 Kinesin motor domain DivIC PF04977.10 GAM26438.1 - 0.0089 15.4 4.2 0.0089 15.4 2.9 7.4 5 3 1 7 7 7 2 Septum formation initiator FAD_binding_4 PF01565.18 GAM26439.1 - 8.7e-27 93.2 0.1 2.2e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Methyltransf_11 PF08241.7 GAM26439.1 - 1.4e-06 28.6 0.0 8.3e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM26439.1 - 1.6e-06 27.9 0.0 4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ALO PF04030.9 GAM26439.1 - 7.1e-06 25.8 0.7 4e-05 23.3 0.3 2.2 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase Methyltransf_25 PF13649.1 GAM26439.1 - 0.0038 17.5 0.0 0.18 12.1 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM26439.1 - 0.0053 17.1 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M24 PF00557.19 GAM26440.1 - 2.1e-45 154.8 0.0 2.6e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 GAM26440.1 - 0.00048 19.9 2.7 0.0012 18.7 1.9 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 GAM26440.1 - 0.012 15.1 6.0 0.03 13.9 4.1 1.7 1 0 0 1 1 1 0 HIT zinc finger mit_SMPDase PF14724.1 GAM26440.1 - 0.22 9.3 0.0 0.3 8.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase Myotub-related PF06602.9 GAM26441.1 - 1.9e-122 408.4 0.6 2.9e-122 407.8 0.4 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 GAM26441.1 - 0.0044 16.6 0.0 0.014 14.9 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAM26441.1 - 0.0068 16.6 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family GRAM PF02893.15 GAM26441.1 - 0.021 14.3 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 GRAM domain 2OG-FeII_Oxy PF03171.15 GAM26442.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM26442.1 - 0.0083 16.6 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DnaJ PF00226.26 GAM26443.1 - 5e-25 87.0 0.6 1.1e-24 85.9 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2890 PF11081.3 GAM26443.1 - 0.0004 20.4 17.9 0.0004 20.4 12.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2890) Pox_Ag35 PF03286.9 GAM26443.1 - 0.0045 16.5 13.3 0.0045 16.5 9.2 2.2 2 0 0 2 2 2 1 Pox virus Ag35 surface protein Daxx PF03344.10 GAM26443.1 - 0.0059 15.1 21.2 0.01 14.3 14.7 1.4 1 0 0 1 1 1 1 Daxx Family Astro_capsid PF03115.9 GAM26443.1 - 0.23 9.6 6.3 0.3 9.2 4.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 GAM26443.1 - 0.36 8.8 17.9 0.032 12.2 9.3 1.5 2 0 0 2 2 2 0 CDC45-like protein AnfO_nitrog PF09582.5 GAM26443.1 - 1.4 7.9 8.0 6.5 5.8 5.4 2.0 1 1 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) COPI_C PF06957.6 GAM26443.1 - 1.6 7.1 9.1 2.2 6.6 6.3 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF913 PF06025.7 GAM26443.1 - 1.9 7.1 6.0 3.7 6.2 4.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 GAM26443.1 - 3 5.4 8.5 3.9 5.0 5.9 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 GAM26443.1 - 3.5 6.5 4.1 5.4 5.9 2.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 GAM26443.1 - 3.8 7.2 9.1 0.52 10.0 3.5 1.8 2 0 0 2 2 2 0 DDHD domain ATPase-cat_bd PF12156.3 GAM26443.1 - 5.4 7.6 8.7 2.1 8.9 0.1 4.0 3 2 2 5 5 5 0 Putative metal-binding domain of cation transport ATPase Spore_coat_CotO PF14153.1 GAM26443.1 - 5.7 6.3 22.3 0.61 9.5 11.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Pkinase PF00069.20 GAM26444.1 - 5.5e-39 133.8 0.1 1.2e-38 132.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26444.1 - 9.9e-25 87.0 0.0 2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM26444.1 - 1.2e-10 41.3 2.0 1.3e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 Ribonuclease 2-5A Ank_2 PF12796.2 GAM26444.1 - 1.4e-05 25.3 5.0 0.00078 19.7 0.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Kdo PF06293.9 GAM26444.1 - 0.00066 18.8 0.2 0.0015 17.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM26444.1 - 0.005 16.2 0.4 0.012 15.0 0.3 1.6 1 0 0 1 1 1 1 RIO1 family Ank_3 PF13606.1 GAM26444.1 - 0.028 14.6 1.9 3.1 8.3 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat PTR2 PF00854.16 GAM26445.1 - 6.1e-83 278.6 10.5 4.3e-68 229.7 1.8 2.7 1 1 2 3 3 3 2 POT family MFS_1 PF07690.11 GAM26445.1 - 5.9e-11 41.6 19.8 4.8e-10 38.6 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF997 PF06196.7 GAM26445.1 - 0.32 10.5 6.4 0.24 10.9 0.2 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF997) YqzM PF14141.1 GAM26445.1 - 0.65 9.8 0.0 0.65 9.8 0.0 2.9 3 0 0 3 3 3 0 YqzM-like protein Orai-1 PF07856.7 GAM26445.1 - 1.8 8.0 8.5 1.5 8.4 3.5 2.1 2 0 0 2 2 2 0 Mediator of CRAC channel activity DUF1045 PF06299.7 GAM26447.1 - 0.0065 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) LigT_PEase PF02834.11 GAM26447.1 - 0.017 15.1 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 GAM26447.1 - 0.077 12.7 0.0 1.1 8.9 0.0 2.1 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily EGF_2 PF07974.8 GAM26448.1 - 3.1e-05 24.0 21.7 0.02 15.0 5.4 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 GAM26448.1 - 0.25 11.3 23.8 0.16 11.9 6.1 2.6 2 0 0 2 2 2 0 EGF-like domain EB PF01683.13 GAM26448.1 - 0.8 9.8 15.7 0.93 9.6 3.6 2.4 1 1 1 2 2 2 0 EB module hEGF PF12661.2 GAM26448.1 - 1.3 9.2 6.6 0.14 12.3 0.4 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF Metallothio PF00131.15 GAM26448.1 - 4.8 7.1 15.7 8.7 6.3 10.9 1.4 1 0 0 1 1 1 0 Metallothionein Pkinase_Tyr PF07714.12 GAM26449.1 - 2.4e-42 144.7 0.0 4.2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26449.1 - 7e-39 133.5 0.0 1.3e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 GAM26449.1 - 1.3e-19 69.3 28.2 1e-05 25.0 0.4 5.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM26449.1 - 1.2e-17 63.4 22.0 3.1e-05 23.6 0.5 5.6 3 2 1 5 5 5 4 Leucine rich repeat Miro PF08477.8 GAM26449.1 - 2.4e-13 50.6 0.1 1.1e-12 48.4 0.0 2.3 2 0 0 2 2 1 1 Miro-like protein Ras PF00071.17 GAM26449.1 - 3.6e-12 45.9 0.5 7.7e-11 41.6 0.3 2.2 1 1 0 1 1 1 1 Ras family Myotub-related PF06602.9 GAM26449.1 - 7.1e-09 34.8 0.4 1.7e-08 33.6 0.2 1.6 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain LRR_1 PF00560.28 GAM26449.1 - 1.3e-07 30.6 28.6 0.0054 16.5 0.2 9.2 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM26449.1 - 4.9e-06 25.8 19.6 0.12 12.7 0.1 9.0 9 1 1 10 10 9 2 Leucine rich repeat GTP_EFTU PF00009.22 GAM26449.1 - 5.4e-06 25.9 0.1 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 GAM26449.1 - 0.00032 19.9 0.1 0.017 14.3 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM26449.1 - 0.00047 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRR_6 PF13516.1 GAM26449.1 - 0.007 16.3 23.3 0.47 10.6 0.1 8.8 12 0 0 12 12 8 1 Leucine Rich repeat Vps36_ESCRT-II PF11605.3 GAM26449.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 MobB PF03205.9 GAM26449.1 - 0.016 14.9 0.1 0.037 13.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Serglycin PF04360.7 GAM26449.1 - 0.04 13.6 2.2 0.044 13.5 0.1 2.1 3 0 0 3 3 2 0 Serglycin SRPRB PF09439.5 GAM26449.1 - 0.042 13.0 0.1 0.11 11.6 0.1 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 GAM26449.1 - 0.044 13.4 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 GAM26449.1 - 0.053 12.5 0.2 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 GAM26449.1 - 0.067 12.6 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation APH PF01636.18 GAM26449.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DnaJ PF00226.26 GAM26450.1 - 6.3e-22 77.0 0.3 6.3e-22 77.0 0.2 1.7 2 0 0 2 2 1 1 DnaJ domain zf-MYND PF01753.13 GAM26450.1 - 9.4e-11 41.4 13.9 9.4e-11 41.4 9.7 1.7 2 0 0 2 2 1 1 MYND finger BAF1_ABF1 PF04684.8 GAM26450.1 - 0.002 17.0 19.6 0.0027 16.6 13.6 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 GAM26450.1 - 0.0021 17.1 0.9 0.0053 15.8 0.6 1.7 1 0 0 1 1 1 1 ZIP Zinc transporter CDK5_activator PF03261.10 GAM26450.1 - 0.32 10.3 12.9 0.46 9.7 8.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AIF_C PF14721.1 GAM26450.1 - 0.83 9.9 4.5 0.22 11.7 0.7 1.8 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ctr PF04145.10 GAM26450.1 - 0.83 9.6 6.9 3 7.8 4.2 2.5 2 1 0 2 2 2 0 Ctr copper transporter family TFIIA PF03153.8 GAM26450.1 - 1.2 8.9 20.3 1.7 8.4 14.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.8 GAM26450.1 - 1.2 8.5 7.6 2.1 7.8 5.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 GAM26450.1 - 1.3 8.8 8.9 3.9 7.2 6.2 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PAT1 PF09770.4 GAM26450.1 - 2.1 6.4 24.6 3 5.9 17.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK2AP PF09806.4 GAM26450.1 - 2.9 8.0 15.2 4.5 7.4 10.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3464 PF11947.3 GAM26450.1 - 4.4 6.7 10.1 15 5.0 7.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4557 PF15101.1 GAM26450.1 - 4.7 6.9 15.3 11 5.8 10.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PEMT PF04191.8 GAM26451.1 - 2.4e-50 169.0 14.1 2e-32 111.4 2.3 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase Merozoite_SPAM PF07133.6 GAM26451.1 - 1.3 8.9 18.1 2.3 8.0 12.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PP2C PF00481.16 GAM26452.1 - 1.6e-53 181.7 2.1 3.6e-52 177.2 0.1 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAM26452.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C Ank_2 PF12796.2 GAM26453.1 - 2.6e-06 27.6 1.7 0.24 11.7 0.0 5.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) FNIP PF05725.7 GAM26454.1 - 1.2e-14 54.0 1.6 1e-09 38.1 0.0 3.7 3 1 0 3 3 3 3 FNIP Repeat CBAH PF02275.13 GAM26454.1 - 0.083 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family FNIP PF05725.7 GAM26455.1 - 1.4e-22 79.3 1.6 9e-13 47.9 0.0 2.8 3 0 0 3 3 3 2 FNIP Repeat NAD_kinase PF01513.16 GAM26457.1 - 4.9e-48 163.3 0.0 6.6e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Pex14_N PF04695.8 GAM26457.1 - 3.6 7.6 10.4 3.1 7.8 6.2 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 GAM26457.1 - 3.8 5.6 10.3 4.9 5.2 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 GAM26457.1 - 9.6 5.0 8.2 17 4.3 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Arf PF00025.16 GAM26458.1 - 9e-37 125.9 0.0 1e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM26458.1 - 5.5e-09 35.5 0.1 6.7e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM26458.1 - 1.3e-07 32.1 0.0 2.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM26458.1 - 1.4e-06 27.7 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM26458.1 - 3e-06 27.1 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM26458.1 - 7.8e-06 24.8 2.0 0.037 12.7 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 GAM26458.1 - 1.1e-05 24.8 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 GAM26458.1 - 0.0061 16.0 0.0 0.12 11.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PI3K_p85B PF02192.11 GAM26458.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 PI3-kinase family, p85-binding domain SLT_beta PF02258.11 GAM26458.1 - 0.055 13.2 0.2 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Shiga-like toxin beta subunit cobW PF02492.14 GAM26458.1 - 0.071 12.5 0.1 2.7 7.3 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PB1 PF00564.19 GAM26460.1 - 0.0013 18.3 0.4 0.0031 17.1 0.3 1.6 1 0 0 1 1 1 1 PB1 domain AUX_IAA PF02309.11 GAM26460.1 - 0.039 13.7 3.4 0.18 11.5 2.3 1.9 1 1 0 1 1 1 0 AUX/IAA family Membrane_bind PF14564.1 GAM26461.1 - 2.1e-31 108.3 0.0 4.5e-31 107.2 0.0 1.5 2 0 0 2 2 2 1 Membrane binding Crystall_3 PF08964.5 GAM26461.1 - 1.4e-18 66.3 0.0 2.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin PagP PF07017.6 GAM26461.1 - 0.036 13.3 0.2 0.065 12.5 0.1 1.7 1 1 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Ribosomal_S10 PF00338.17 GAM26462.1 - 4e-20 71.4 0.1 4.9e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PTPlike_phytase PF14566.1 GAM26463.1 - 0.26 11.3 4.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate C2 PF00168.25 GAM26464.1 - 0.00031 20.5 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain HATPase_c PF02518.21 GAM26465.1 - 6.9e-29 99.8 0.1 1.5e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE PF03924.8 GAM26465.1 - 2.8e-23 82.1 0.0 6.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 CHASE domain Response_reg PF00072.19 GAM26465.1 - 2.8e-22 78.8 0.1 9.8e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAM26465.1 - 2.3e-21 75.5 0.0 7.1e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 GAM26465.1 - 1.6e-08 34.5 0.0 4.1e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 GAM26465.1 - 0.00011 22.5 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 GAM26465.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FMN_red PF03358.10 GAM26466.1 - 5e-30 104.0 0.0 6.5e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 GAM26466.1 - 2.3e-07 30.5 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Aminotran_3 PF00202.16 GAM26467.1 - 2.5e-94 315.9 0.0 2.9e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TAXi_C PF14541.1 GAM26468.1 - 7.6e-12 45.0 1.5 1e-11 44.6 0.0 2.0 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp PF00026.18 GAM26468.1 - 3e-11 43.1 0.0 5.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TSP_1 PF00090.14 GAM26468.1 - 0.005 16.9 5.0 0.005 16.9 3.5 4.5 4 1 0 4 4 4 2 Thrombospondin type 1 domain Chordopox_A20R PF05941.8 GAM26471.1 - 0.056 12.1 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A20R protein Yeast-kill-tox PF09207.6 GAM26471.1 - 0.29 11.6 1.4 0.38 11.2 0.2 1.7 2 0 0 2 2 2 0 Yeast killer toxin DUF4212 PF13937.1 GAM26472.1 - 0.00025 20.9 7.1 0.03 14.3 3.5 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4212) DUF2547 PF10818.3 GAM26472.1 - 0.56 10.8 2.8 0.71 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Esterase_phd PF10503.4 GAM26473.1 - 4.7e-10 39.0 1.6 4.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Peptidase_S9 PF00326.16 GAM26473.1 - 0.021 14.0 0.1 0.041 13.0 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_S4e PF00900.15 GAM26474.1 - 1.7e-23 82.1 0.2 2.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 GAM26474.1 - 6.4e-18 64.3 6.8 1.3e-17 63.3 4.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 GAM26474.1 - 4.7e-10 38.7 0.0 8.5e-10 37.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 GAM26474.1 - 8.8e-05 22.0 2.0 0.00011 21.7 0.0 2.3 3 0 0 3 3 3 1 KOW motif Ribosomal_60s PF00428.14 GAM26475.1 - 0.024 15.0 3.5 0.054 13.9 2.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3672 PF12421.3 GAM26475.1 - 2.7 8.1 13.5 0.16 12.1 5.1 2.1 2 0 0 2 2 2 0 Fibronectin type III protein Pkinase PF00069.20 GAM26476.1 - 1.9e-40 138.6 0.0 2.4e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26476.1 - 3.8e-27 94.9 0.0 5.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 GAM26476.1 - 3.7e-14 52.6 0.3 8.3e-14 51.5 0.2 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A APH PF01636.18 GAM26476.1 - 0.00023 21.0 0.1 0.024 14.3 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 GAM26476.1 - 0.0086 15.4 0.2 0.036 13.4 0.2 1.9 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM26476.1 - 0.075 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.26 GAM26477.1 - 4.3e-23 81.4 0.4 1.2e-21 76.7 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain DUF572 PF04502.8 GAM26477.1 - 0.0029 16.9 20.5 0.0051 16.0 14.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) AAA_23 PF13476.1 GAM26477.1 - 0.66 10.2 12.2 0.018 15.3 3.0 2.4 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.18 GAM26478.1 - 4.9e-27 93.7 1.2 7e-27 93.2 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM26478.1 - 6.8e-05 22.9 0.1 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 GAM26478.1 - 0.003 17.3 0.1 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF3439 PF11921.3 GAM26478.1 - 0.0059 16.3 5.9 0.0059 16.3 4.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) MOR2-PAG1_N PF14222.1 GAM26478.1 - 0.026 13.2 4.0 0.032 12.9 2.8 1.0 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Bromo_TP PF07524.8 GAM26478.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated SSP160 PF06933.6 GAM26478.1 - 0.11 10.5 5.9 0.14 10.1 4.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tmemb_cc2 PF10267.4 GAM26478.1 - 0.13 10.8 4.0 0.17 10.4 2.8 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF566 PF04484.7 GAM26478.1 - 2.8 7.3 11.3 1.6 8.1 6.5 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF566) VWA_3 PF13768.1 GAM26479.1 - 1.5e-30 105.9 0.4 5.7e-29 100.8 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 GAM26479.1 - 1.9e-22 79.1 0.5 1.9e-22 79.1 0.4 3.6 2 1 1 4 4 4 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAM26479.1 - 4.3e-12 46.1 0.0 4.3e-12 46.1 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAM26479.1 - 3.4e-07 29.6 0.0 9.2e-07 28.2 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain AAA_23 PF13476.1 GAM26479.1 - 0.3 11.4 26.5 0.19 12.0 16.0 2.3 2 0 0 2 2 2 0 AAA domain Nop53 PF07767.6 GAM26479.1 - 6 5.7 31.1 0.23 10.4 17.3 1.7 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) eIF-3_zeta PF05091.7 GAM26479.1 - 9.6 4.6 33.7 0.086 11.4 16.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) 7tm_3 PF00003.17 GAM26480.1 - 3.2e-19 69.2 25.3 3.2e-19 69.2 17.5 2.2 2 1 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Serglycin PF04360.7 GAM26480.1 - 0.068 12.8 2.5 0.17 11.6 1.8 1.6 1 0 0 1 1 1 0 Serglycin Glycophorin_A PF01102.13 GAM26480.1 - 4.8 6.9 9.6 0.44 10.3 0.4 2.8 2 0 0 2 2 2 0 Glycophorin A Pkinase PF00069.20 GAM26482.1 - 3e-58 197.0 0.0 4.5e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26482.1 - 1e-39 136.2 0.0 1.9e-39 135.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM26482.1 - 2.2e-05 23.5 0.0 4.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Macoilin PF09726.4 GAM26482.1 - 2.2 6.4 15.4 2.8 6.0 10.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Period_C PF12114.3 GAM26482.1 - 2.7 7.5 14.8 5.3 6.6 10.3 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.4 GAM26482.1 - 9.1 5.6 15.4 14 5.0 10.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CS PF04969.11 GAM26483.1 - 1.1e-09 38.6 0.1 1.6e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 GAM26483.1 - 0.029 14.7 10.8 0.043 14.2 7.5 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region EFhand_Ca_insen PF08726.5 GAM26483.1 - 0.095 12.6 0.2 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand PAP2 PF01569.16 GAM26484.1 - 1.7e-18 66.5 6.9 2.6e-18 65.9 1.5 2.2 1 1 1 2 2 2 2 PAP2 superfamily DUF805 PF05656.9 GAM26484.1 - 0.33 10.7 10.2 0.068 13.0 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ATP12 PF07542.6 GAM26485.1 - 2.4e-32 111.4 0.0 4e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein SRX PF09201.5 GAM26485.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 SRX Pkinase PF00069.20 GAM26486.1 - 3.2e-08 33.0 0.1 5.7e-08 32.2 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26486.1 - 3.1e-05 23.1 0.0 4.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM26486.1 - 0.016 14.1 0.2 0.042 12.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Mad3_BUB1_I PF08311.7 GAM26487.1 - 1.3e-36 125.1 0.2 2.4e-36 124.3 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 EamA PF00892.15 GAM26488.1 - 1.5e-09 37.9 39.2 1.2e-06 28.5 8.9 3.3 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 GAM26488.1 - 0.0034 17.5 4.2 0.0034 17.5 2.9 3.0 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 GAM26488.1 - 0.0093 14.9 23.6 0.14 11.0 16.2 2.5 1 1 0 1 1 1 1 UAA transporter family Pox_A14 PF05767.7 GAM26488.1 - 0.012 15.5 0.8 0.012 15.5 0.5 4.2 3 2 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2627 PF11118.3 GAM26488.1 - 0.089 12.9 1.1 0.42 10.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) zf-C3HC4_2 PF13923.1 GAM26489.1 - 2.3e-06 27.5 8.2 2.3e-06 27.5 5.7 4.7 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM26489.1 - 5.8e-06 26.0 7.8 5.8e-06 26.0 5.4 3.9 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 GAM26489.1 - 1.6e-05 24.4 8.1 1.6e-05 24.4 5.6 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 GAM26489.1 - 2e-05 24.3 44.4 2.3e-05 24.1 6.7 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_3 PF13920.1 GAM26489.1 - 0.00041 19.9 6.4 0.00041 19.9 4.5 4.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM26489.1 - 0.0068 16.1 8.2 0.0068 16.1 5.7 3.9 3 1 0 3 3 3 2 zinc-RING finger domain Exo_endo_phos PF03372.18 GAM26490.1 - 8.1e-32 111.1 0.0 1.4e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RCC1 PF00415.13 GAM26490.1 - 3.8e-18 65.4 0.4 4e-08 33.3 0.0 3.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM26490.1 - 2.1e-05 24.0 1.0 0.011 15.3 0.0 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 GAM26491.1 - 2.7e-44 149.1 7.4 2.3e-14 53.3 0.2 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM26491.1 - 4.9e-29 99.2 21.7 2e-08 33.6 0.2 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat CENP-S PF15630.1 GAM26492.1 - 2.2e-21 75.8 0.1 4.4e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 GAM26492.1 - 0.0004 20.4 0.0 0.00073 19.5 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 GAM26492.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 3.3 3 1 0 3 3 2 1 Centromere kinetochore component CENP-T TAF PF02969.12 GAM26492.1 - 0.018 14.9 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) RAP1 PF07218.6 GAM26492.1 - 0.13 10.2 17.2 0.17 9.9 11.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pol_alpha_B_N PF08418.5 GAM26492.1 - 0.43 10.0 25.6 0.31 10.5 16.2 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.4 GAM26492.1 - 0.55 8.4 20.6 0.76 7.9 14.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Cut8_N PF14482.1 GAM26492.1 - 0.66 10.0 0.0 0.66 10.0 0.0 5.0 3 1 0 3 3 2 0 Cut8 proteasome-binding domain Ndc1_Nup PF09531.5 GAM26492.1 - 0.71 8.2 8.1 0.77 8.1 5.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF566 PF04484.7 GAM26492.1 - 1 8.8 19.9 1.8 8.0 13.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3337 PF11816.3 GAM26492.1 - 1 8.6 19.1 2 7.7 13.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) CytochromB561_N PF09786.4 GAM26492.1 - 1.9 6.8 15.4 2.5 6.4 10.7 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1675 PF07897.6 GAM26492.1 - 2 8.2 18.9 4.2 7.1 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S64 PF08192.6 GAM26492.1 - 2.4 6.3 17.6 2.9 6.1 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 MAP65_ASE1 PF03999.7 GAM26492.1 - 4.7 5.6 17.3 6.6 5.1 12.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NST1 PF13945.1 GAM26492.1 - 6.3 6.8 19.0 15 5.6 13.2 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator DNA_pol_viral_N PF00242.12 GAM26492.1 - 8.2 5.3 22.6 13 4.6 15.7 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SDA1 PF05285.7 GAM26493.1 - 1e-62 212.3 58.0 1e-62 212.3 40.2 2.7 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 GAM26493.1 - 8.5e-20 70.7 0.2 2.6e-19 69.2 0.1 1.9 1 0 0 1 1 1 1 NUC130/3NT domain BolA PF01722.13 GAM26495.1 - 8.9e-30 102.4 0.1 1.2e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein ECH PF00378.15 GAM26496.1 - 1.2e-23 83.4 0.0 1.5e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 GAM26497.1 - 2.6e-30 105.3 0.0 3.3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4203 PF13886.1 GAM26497.1 - 0.059 12.8 0.2 0.087 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) OAS1_C PF10421.4 GAM26498.1 - 3.9e-24 85.2 1.7 8e-24 84.1 1.2 1.5 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus NTP_transf_2 PF01909.18 GAM26498.1 - 0.0015 18.8 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Herpes_BLRF2 PF05812.7 GAM26498.1 - 0.043 13.6 0.5 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein NPV_P10 PF05531.7 GAM26498.1 - 0.073 13.3 1.4 0.16 12.2 0.0 2.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MOR2-PAG1_N PF14222.1 GAM26500.1 - 4.2e-97 326.1 2.4 1.9e-96 323.9 0.5 2.8 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.1 GAM26500.1 - 7.7e-75 252.3 10.2 1.4e-28 99.1 2.1 3.1 2 1 1 3 3 3 3 Cell morphogenesis central region MOR2-PAG1_C PF14225.1 GAM26500.1 - 3e-41 141.9 0.8 2.5e-40 138.8 0.0 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal Aminotran_5 PF00266.14 GAM26501.1 - 1.2e-93 313.7 0.0 1.5e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 GAM26501.1 - 6.2e-11 41.9 0.0 8.7e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAM26501.1 - 5.6e-07 28.9 0.0 8.2e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 GAM26501.1 - 0.0032 15.8 0.0 0.0049 15.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.14 GAM26501.1 - 0.0082 14.6 0.0 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain PWWP PF00855.12 GAM26502.1 - 3.6e-07 30.2 0.0 3.6e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 PWWP domain COPIIcoated_ERV PF07970.7 GAM26503.1 - 8.5e-73 244.6 1.1 1.3e-72 243.9 0.8 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 GAM26503.1 - 7.2e-33 112.4 0.5 1.3e-31 108.3 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SH3_1 PF00018.23 GAM26504.1 - 9.8e-23 79.2 1.6 1.2e-10 40.5 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 GAM26504.1 - 1.6e-21 75.5 1.6 8.9e-11 41.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 GAM26504.1 - 7.9e-19 66.9 2.3 1.1e-08 34.5 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain CS PF04969.11 GAM26504.1 - 4.3e-05 23.9 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 CS domain Glutaminase PF04960.10 GAM26504.1 - 0.017 14.1 0.0 0.046 12.6 0.0 1.8 1 1 0 1 1 1 0 Glutaminase DUF1115 PF06544.7 GAM26505.1 - 2.5e-30 104.7 0.0 5.8e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PRP3 PF08572.5 GAM26505.1 - 1.1e-23 83.8 5.7 1.1e-23 83.8 3.9 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) Abhydrolase_6 PF12697.2 GAM26506.1 - 2.1e-35 122.6 0.0 3e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM26506.1 - 1.4e-18 67.3 0.0 3.1e-13 49.7 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM26506.1 - 1.1e-14 54.3 0.0 3.9e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM26506.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 GAM26506.1 - 0.0013 18.3 0.0 0.0041 16.7 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 GAM26506.1 - 0.0042 17.3 0.0 0.0069 16.6 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain DUF915 PF06028.6 GAM26506.1 - 0.0047 16.0 0.0 0.25 10.4 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 GAM26506.1 - 0.018 14.3 0.1 0.044 13.0 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 GAM26506.1 - 0.021 14.2 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 GAM26506.1 - 0.078 12.5 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) DUF2305 PF10230.4 GAM26506.1 - 0.11 11.8 0.0 6.2 6.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) AhpC-TSA PF00578.16 GAM26507.1 - 5.2e-31 106.8 0.0 6.8e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM26507.1 - 6.8e-08 32.1 0.0 8.3e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAM26507.1 - 3.8e-07 29.6 0.1 1.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin MRP-S28 PF10213.4 GAM26508.1 - 8.1e-12 45.3 1.7 1.6e-11 44.3 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein RF-1 PF00472.15 GAM26508.1 - 0.031 14.0 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 RF-1 domain PTPS PF01242.14 GAM26509.1 - 0.009 15.6 4.3 1.8 8.2 0.1 2.6 2 0 0 2 2 2 2 6-pyruvoyl tetrahydropterin synthase RabGAP-TBC PF00566.13 GAM26510.1 - 7.9e-44 149.6 1.2 7.9e-44 149.6 0.8 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NYD-SP28_assoc PF14775.1 GAM26510.1 - 0.05 13.3 5.4 0.15 11.7 3.7 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain IncA PF04156.9 GAM26510.1 - 0.12 11.9 12.3 0.38 10.3 8.5 1.9 1 0 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 GAM26510.1 - 0.83 8.8 6.5 2 7.5 4.5 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF972 PF06156.8 GAM26510.1 - 1.4 9.2 11.1 6.4 7.1 7.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 GAM26510.1 - 1.9 7.9 8.4 1.3 8.5 3.3 2.3 1 1 1 2 2 2 0 Septum formation initiator Adap_comp_sub PF00928.16 GAM26511.1 - 1.6e-75 253.6 0.0 1.9e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM26511.1 - 0.0012 18.5 0.1 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain bZIP_1 PF00170.16 GAM26512.1 - 1.4e-13 50.5 5.5 1.4e-13 50.5 3.8 1.7 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 GAM26512.1 - 5.4e-12 45.3 2.8 1.3e-11 44.1 2.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Shugoshin_N PF07558.6 GAM26512.1 - 0.0028 17.3 0.1 0.0071 16.0 0.1 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_Maf PF03131.12 GAM26512.1 - 0.0029 17.8 4.9 0.0029 17.8 3.4 2.1 1 1 1 2 2 2 1 bZIP Maf transcription factor XPC-binding PF09280.6 GAM26512.1 - 0.0038 16.6 0.4 0.0097 15.3 0.3 1.7 1 0 0 1 1 1 1 XPC-binding domain HAP1_N PF04849.8 GAM26512.1 - 0.015 14.2 4.2 0.027 13.4 2.9 1.4 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CCDC155 PF14662.1 GAM26512.1 - 0.017 14.7 5.3 0.03 13.9 3.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 GAM26512.1 - 0.018 14.8 4.1 0.033 14.0 2.8 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.13 GAM26512.1 - 0.13 12.2 0.6 0.34 10.9 0.4 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 GAM26512.1 - 0.15 12.4 0.7 0.37 11.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 GAM26512.1 - 0.33 10.5 5.8 0.29 10.7 2.7 1.8 2 0 0 2 2 2 0 IncA protein Macoilin PF09726.4 GAM26512.1 - 0.79 7.9 20.9 0.024 12.9 10.2 1.5 2 0 0 2 2 2 0 Transmembrane protein Patatin PF01734.17 GAM26513.1 - 4.7e-17 62.5 1.3 8e-17 61.8 0.9 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 GAM26514.1 - 9.2e-15 55.1 1.9 2e-14 54.0 1.3 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Asn_synthase PF00733.16 GAM26515.1 - 5.7e-30 104.6 0.0 1.7e-29 103.1 0.0 1.7 1 1 0 1 1 1 1 Asparagine synthase QueC PF06508.8 GAM26515.1 - 0.00067 18.9 0.0 0.0028 16.9 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC zf-ribbon_3 PF13248.1 GAM26515.1 - 0.027 13.6 2.0 0.084 12.1 1.4 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 GAM26515.1 - 0.053 13.3 3.1 0.054 13.3 0.7 2.1 2 0 0 2 2 2 0 Double zinc ribbon MarR_2 PF12802.2 GAM26515.1 - 0.1 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 MarR family Patatin PF01734.17 GAM26516.1 - 1.4e-16 61.0 0.3 2.5e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Kelch_6 PF13964.1 GAM26517.1 - 4.3e-10 39.3 5.4 0.065 13.4 0.1 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM26517.1 - 7.2e-07 28.8 7.0 0.23 11.2 0.0 5.8 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM26517.1 - 1.4e-05 24.5 5.0 0.27 10.8 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM26517.1 - 4.7e-05 22.9 0.4 2.4 8.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 GAM26517.1 - 7.8e-05 22.7 1.5 7.2 6.9 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM26517.1 - 1.5 8.8 14.5 1.9 8.5 0.2 3.9 4 0 0 4 4 4 0 Kelch motif Pkinase_Tyr PF07714.12 GAM26519.1 - 1e-54 185.3 0.0 1.5e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26519.1 - 1.1e-50 172.1 0.0 2.2e-50 171.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Microtub_bind PF13931.1 GAM26520.1 - 0.042 13.9 0.3 0.042 13.9 0.2 1.0 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding RE_MjaI PF09568.5 GAM26520.1 - 0.091 12.2 0.3 0.089 12.3 0.2 1.1 1 0 0 1 1 1 0 MjaI restriction endonuclease DNA_pol_E_B PF04042.11 GAM26521.1 - 8.6e-47 159.0 1.1 1.3e-46 158.5 0.3 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 GAM26521.1 - 1.3e-10 41.0 0.4 3.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 DNA polymerases epsilon N terminal BRO1 PF03097.13 GAM26522.1 - 8.3e-35 120.2 1.4 1.1e-34 119.8 0.1 1.8 1 1 1 2 2 2 1 BRO1-like domain CDC45 PF02724.9 GAM26522.1 - 0.00099 17.2 12.5 0.00099 17.2 8.7 2.1 2 0 0 2 2 2 1 CDC45-like protein Vfa1 PF08432.5 GAM26522.1 - 0.88 9.5 27.8 0.054 13.5 9.7 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 GAM26522.1 - 1.3 7.9 3.2 0.82 8.6 0.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter CobT PF06213.7 GAM26522.1 - 2.1 7.3 29.9 0.03 13.4 13.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RhoGAP PF00620.22 GAM26524.1 - 3.5e-27 94.8 0.9 5.7e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain Motile_Sperm PF00635.21 GAM26524.1 - 0.081 12.5 0.4 0.2 11.3 0.2 1.6 2 0 0 2 2 2 0 MSP (Major sperm protein) domain DEAD PF00270.24 GAM26525.1 - 2.7e-18 66.0 0.0 6e-17 61.6 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM26525.1 - 1.2e-17 63.5 0.2 4.5e-17 61.6 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 GAM26525.1 - 1.4e-14 54.3 0.0 1.4e-14 54.3 0.0 3.6 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit Mucin PF01456.12 GAM26526.1 - 9.5 5.9 39.4 0.16 11.7 9.1 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein Pyrid_oxidase_2 PF13883.1 GAM26527.1 - 3e-09 36.8 0.0 4.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.4 GAM26527.1 - 5.7e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2470) Myb_DNA-binding PF00249.26 GAM26528.1 - 1.6e-12 47.2 0.1 2.8e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM26528.1 - 0.0024 17.9 0.1 0.0081 16.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain E1-E2_ATPase PF00122.15 GAM26529.1 - 2.4e-59 200.1 1.7 2.4e-59 200.1 1.2 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM26529.1 - 9.9e-46 155.5 7.5 9.9e-46 155.5 5.2 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM26529.1 - 2.3e-26 93.5 0.1 5.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM26529.1 - 6.3e-18 64.5 0.0 1.5e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM26529.1 - 4.1e-15 56.4 0.0 9.4e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM26529.1 - 7.4e-15 54.1 0.4 1.3e-13 50.1 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM26529.1 - 0.0001 22.0 3.1 0.036 13.6 0.1 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase V-ATPase_H_N PF03224.9 GAM26531.1 - 7.6e-59 199.3 1.3 1.6e-58 198.2 0.9 1.5 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAM26531.1 - 2.1e-46 156.7 3.3 3.3e-44 149.6 0.4 2.5 2 0 0 2 2 2 2 V-ATPase subunit H Arm_2 PF04826.8 GAM26531.1 - 2.5e-05 23.5 0.2 0.005 15.9 0.0 2.3 2 0 0 2 2 2 2 Armadillo-like Arm PF00514.18 GAM26531.1 - 0.00096 18.8 0.0 14 5.6 0.0 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM26531.1 - 0.0025 18.0 0.0 0.15 12.3 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 GAM26531.1 - 0.1 13.0 0.1 1.6 9.3 0.0 2.9 2 2 2 4 4 4 0 HEAT-like repeat Glyco_hydro_18 PF00704.23 GAM26532.1 - 2e-23 83.4 5.2 8.7e-22 78.0 2.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 TatD_DNase PF01026.16 GAM26533.1 - 5.7e-60 202.6 0.0 6.9e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase ERG2_Sigma1R PF04622.7 GAM26534.1 - 2.4e-40 138.1 0.0 2.9e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Amastin PF07344.6 GAM26534.1 - 0.063 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Amastin surface glycoprotein FNIP PF05725.7 GAM26535.1 - 8e-101 329.8 34.5 1.3e-15 57.0 1.4 11.9 13 0 0 13 13 13 11 FNIP Repeat Pkinase_Tyr PF07714.12 GAM26536.1 - 2.5e-60 203.7 0.0 3.3e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26536.1 - 4.8e-51 173.4 0.0 6.6e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.17 GAM26536.1 - 3.7e-17 62.1 22.6 2.6e-08 33.8 4.7 2.6 2 0 0 2 2 2 2 LIM domain APH PF01636.18 GAM26536.1 - 0.0023 17.6 0.0 0.0049 16.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM26536.1 - 0.0041 16.1 0.0 0.0075 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM26536.1 - 0.0077 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 GAM26536.1 - 0.012 15.0 0.4 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family DUF2318 PF10080.4 GAM26536.1 - 3.5 7.4 12.2 1 9.1 1.8 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) WD40 PF00400.27 GAM26537.1 - 2.1e-41 138.3 8.1 5.9e-12 44.9 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM26537.1 - 0.12 10.5 0.1 0.21 9.7 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 TK PF00265.13 GAM26538.1 - 1.9e-65 219.6 0.1 2.2e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 GAM26538.1 - 0.0043 16.9 0.1 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM26538.1 - 0.041 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase TIP41 PF04176.8 GAM26538.1 - 0.096 11.9 0.1 0.17 11.1 0.0 1.3 1 1 0 1 1 1 0 TIP41-like family Herpes_ori_bp PF02399.10 GAM26538.1 - 0.13 10.2 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein GGDEF PF00990.16 GAM26539.1 - 1.9e-34 118.5 0.0 3.5e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 GGDEF domain LRR_6 PF13516.1 GAM26540.1 - 1.3e-10 40.1 18.4 0.24 11.5 0.0 9.9 9 1 1 10 10 10 3 Leucine Rich repeat RasGAP PF00616.14 GAM26540.1 - 2.4e-08 33.8 1.6 2.4e-08 33.8 1.1 3.8 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase LRR_4 PF12799.2 GAM26540.1 - 1.3e-05 24.6 27.1 0.046 13.3 2.8 6.9 5 3 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM26540.1 - 0.00019 21.0 18.8 0.065 12.9 3.6 5.8 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 GAM26540.1 - 0.18 11.9 17.6 8.4 6.8 0.2 8.0 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 GAM26540.1 - 0.24 11.7 12.1 1.6e+02 3.2 0.0 7.8 8 1 0 8 8 8 0 Leucine rich repeat EB PF01683.13 GAM26541.1 - 0.0022 18.0 3.7 0.0022 18.0 2.6 7.7 2 2 4 6 6 6 4 EB module MMS22L_C PF14911.1 GAM26542.1 - 0.038 13.0 1.3 0.048 12.7 0.4 1.5 2 0 0 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal CedA PF10729.4 GAM26543.1 - 0.13 11.8 0.3 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Cell division activator CedA F-box PF00646.28 GAM26544.1 - 0.51 10.0 3.3 0.21 11.3 0.3 1.8 2 0 0 2 2 2 0 F-box domain Astro_capsid PF03115.9 GAM26548.1 - 0.23 9.6 1.5 0.32 9.1 1.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor F-box PF00646.28 GAM26548.1 - 0.26 10.9 3.1 0.18 11.5 0.2 2.1 2 0 0 2 2 2 0 F-box domain Nop14 PF04147.7 GAM26548.1 - 0.4 8.5 10.2 0.64 7.8 7.1 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 GAM26548.1 - 0.77 9.2 12.4 1.5 8.2 8.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin Prothymosin PF03247.9 GAM26548.1 - 0.99 9.5 20.1 1.7 8.8 13.9 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family TRAP_alpha PF03896.11 GAM26548.1 - 2.3 7.1 5.7 6.8 5.5 4.1 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 GAM26548.1 - 5.5 5.6 19.6 8.3 5.0 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CesT PF05932.8 GAM26550.1 - 0.039 13.7 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Tir chaperone protein (CesT) family DUF1888 PF08985.6 GAM26550.1 - 0.13 11.9 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1888) Rad51 PF08423.6 GAM26551.1 - 8.1e-38 129.7 0.1 3.3e-35 121.2 0.1 2.0 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 GAM26551.1 - 1e-12 47.8 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 GAM26551.1 - 1.3e-06 27.7 0.3 5e-06 25.7 0.2 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 GAM26551.1 - 1.7e-05 23.8 0.1 2.7e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.16 GAM26551.1 - 2.8e-05 23.3 0.1 0.0011 18.0 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein FWWh PF14922.1 GAM26551.1 - 0.042 13.3 0.1 0.77 9.2 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function AAA_22 PF13401.1 GAM26551.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM26551.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 GAM26551.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CobU PF02283.11 GAM26551.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase IstB_IS21 PF01695.12 GAM26551.1 - 0.14 11.5 0.1 3 7.2 0.0 2.4 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 GAM26551.1 - 0.15 12.8 0.0 0.42 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain PITH PF06201.8 GAM26552.1 - 2.3e-41 141.0 0.1 2.9e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 PITH domain Tubulin PF00091.20 GAM26553.1 - 9.1e-69 231.5 0.0 1.4e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM26553.1 - 1.6e-47 160.6 0.1 2.6e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAM26553.1 - 0.00071 19.0 0.0 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 1 Tubulin domain Tubulin PF00091.20 GAM26554.1 - 1.6e-69 234.0 0.0 2.4e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM26554.1 - 3e-47 159.7 0.1 5.2e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 GAM26554.1 - 0.00018 20.9 0.0 0.00041 19.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 GAM26555.1 - 7.3e-20 70.3 0.1 1.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM26555.1 - 5.2e-10 39.1 0.0 1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM26555.1 - 0.00032 20.4 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RWD PF05773.17 GAM26556.1 - 2.6e-16 59.5 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 GAM26556.1 - 1.4e-12 47.2 54.2 2.1e-07 30.6 3.6 5.3 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 GAM26556.1 - 0.014 15.2 9.6 0.014 15.2 6.6 5.3 4 2 1 5 5 5 0 Ring finger domain Dicty_REP PF05086.7 GAM26556.1 - 0.017 12.8 0.0 0.022 12.5 0.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 GAM26556.1 - 0.044 11.7 8.4 0.066 11.1 5.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FYVE_2 PF02318.11 GAM26556.1 - 2.9 7.8 41.7 0.18 11.7 4.3 4.3 3 1 1 4 4 4 0 FYVE-type zinc finger Kri1 PF05178.7 GAM26557.1 - 0.72 10.1 2.8 0.75 10.0 1.9 1.1 1 0 0 1 1 1 0 KRI1-like family RasGAP PF00616.14 GAM26558.1 - 5.8e-34 117.4 0.1 5.7e-33 114.2 0.0 2.5 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 GAM26558.1 - 8.8e-17 61.3 1.6 1.9e-16 60.3 1.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 GAM26558.1 - 3.5e-13 49.3 2.2 8e-13 48.1 1.5 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain TSA PF03249.8 GAM26558.1 - 0.0028 16.2 7.0 0.0049 15.4 4.8 1.3 1 0 0 1 1 1 1 Type specific antigen Ras PF00071.17 GAM26559.1 - 3.4e-32 111.0 0.0 4e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM26559.1 - 1.8e-13 50.0 0.0 2.2e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM26559.1 - 2.1e-09 37.9 0.0 2.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 GAM26559.1 - 0.0015 18.1 0.1 0.52 9.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain SRPRB PF09439.5 GAM26559.1 - 0.014 14.6 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 GAM26559.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM26559.1 - 0.024 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM26559.1 - 0.1 11.6 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region CAP PF00188.21 GAM26560.1 - 8.9e-10 39.1 0.5 1.2e-09 38.7 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PRA1 PF03208.14 GAM26560.1 - 1.2 8.4 5.0 1.7 7.9 3.4 1.2 1 0 0 1 1 1 0 PRA1 family protein Ribosomal_L7Ae PF01248.21 GAM26561.1 - 3.9e-21 74.3 0.2 7.7e-21 73.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_60s PF00428.14 GAM26561.1 - 1.3 9.4 13.3 2.8 8.3 1.7 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein ParA PF10609.4 GAM26562.1 - 1.2e-32 111.5 1.2 2.2e-32 110.7 0.2 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 GAM26562.1 - 2e-19 69.7 0.0 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 GAM26562.1 - 7.8e-08 31.7 0.1 1.4e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 GAM26562.1 - 1.5e-05 24.9 0.1 5.3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 GAM26562.1 - 5.7e-05 22.3 0.1 0.00064 18.8 0.0 2.4 2 1 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 GAM26562.1 - 5.9e-05 22.7 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM26562.1 - 0.00049 19.3 0.7 0.0019 17.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 GAM26562.1 - 0.0012 18.1 0.0 0.042 13.0 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArgK PF03308.11 GAM26562.1 - 0.0088 14.8 0.1 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 GAM26562.1 - 0.031 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 GAM26562.1 - 0.063 12.6 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.15 GAM26562.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase YhjQ PF06564.7 GAM26562.1 - 0.13 11.5 0.1 0.23 10.8 0.1 1.5 1 1 0 1 1 1 0 YhjQ protein RseC_MucC PF04246.7 GAM26562.1 - 9.9 5.7 7.2 3.9 7.0 0.4 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Cullin PF00888.17 GAM26563.1 - 1.7e-186 621.2 29.1 2.4e-186 620.7 20.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 GAM26563.1 - 1.8e-29 101.3 6.1 6.2e-29 99.6 4.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.5 GAM26563.1 - 0.098 12.2 0.0 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain DUF2436 PF10365.4 GAM26563.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) MutL_C PF08676.6 GAM26564.1 - 1.8e-16 60.0 0.0 4.2e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 GAM26564.1 - 7.1e-08 31.9 0.1 2.7e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAM26564.1 - 1.5e-07 31.1 0.0 4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM26564.1 - 0.00042 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Neur_chan_memb PF02932.11 GAM26564.1 - 5.4 6.8 9.5 0.32 10.8 0.5 3.2 2 2 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rieske PF00355.21 GAM26565.1 - 1.2e-17 63.2 0.0 2.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 GAM26565.1 - 1.8e-12 47.2 0.1 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Ribosomal_S9 PF00380.14 GAM26566.1 - 1.6e-35 121.9 0.0 1.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Atg14 PF10186.4 GAM26568.1 - 2.3e-32 112.1 13.0 3e-32 111.7 9.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF155 PF02582.9 GAM26568.1 - 0.067 13.0 2.7 0.078 12.8 1.0 1.7 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 DZR PF12773.2 GAM26568.1 - 0.14 11.9 1.7 0.27 11.1 1.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon IncA PF04156.9 GAM26568.1 - 0.25 10.9 10.2 0.44 10.1 6.8 1.6 1 1 0 1 1 1 0 IncA protein ARGLU PF15346.1 GAM26568.1 - 0.54 10.0 12.0 1 9.1 8.3 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Ribosomal_S15 PF00312.17 GAM26568.1 - 8.9 6.1 11.5 0.17 11.6 0.9 2.9 2 1 2 4 4 4 0 Ribosomal protein S15 Glyco_transf_10 PF00852.14 GAM26569.1 - 2.2e-44 151.4 0.4 3.7e-44 150.7 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Laminin_G_3 PF13385.1 GAM26569.1 - 5.7e-11 42.8 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TPR_11 PF13414.1 GAM26570.1 - 5.3e-23 80.4 26.1 4.3e-07 29.4 0.0 8.3 8 1 1 9 9 9 5 TPR repeat TPR_12 PF13424.1 GAM26570.1 - 6.5e-17 61.2 16.6 0.0061 16.4 1.0 8.3 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26570.1 - 3.4e-16 58.2 0.7 0.12 13.0 0.0 9.1 6 2 4 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26570.1 - 1.3e-15 55.9 27.0 0.0062 16.3 0.8 11.0 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26570.1 - 1.1e-14 54.6 11.8 0.0023 18.5 0.0 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 GAM26570.1 - 5.9e-13 47.8 27.6 9.3e-05 21.8 1.4 9.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26570.1 - 2.1e-10 40.7 10.4 0.11 12.8 0.0 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM26570.1 - 1.3e-09 38.0 22.9 0.00055 20.0 0.2 6.6 6 1 0 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAM26570.1 - 1.5e-09 36.9 9.0 0.008 15.9 0.1 8.6 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26570.1 - 4.7e-09 35.7 11.3 1.7 9.0 0.0 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26570.1 - 1.1e-08 34.2 40.1 0.052 13.3 1.3 10.9 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAM26570.1 - 5.8e-05 22.8 0.7 0.43 10.4 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26570.1 - 0.00048 20.3 19.8 0.38 11.3 0.9 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM26570.1 - 0.00071 19.6 1.5 20 5.3 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1798 PF08807.5 GAM26570.1 - 0.011 15.4 1.5 1.3 8.7 0.1 3.4 2 1 1 3 3 3 0 Bacterial domain of unknown function (DUF1798) Rapsyn_N PF10579.4 GAM26570.1 - 0.02 14.6 0.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.4 GAM26570.1 - 0.025 14.4 3.5 13 5.6 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat OGG_N PF07934.7 GAM26570.1 - 0.081 12.8 0.3 0.83 9.6 0.0 2.9 3 1 0 3 3 2 0 8-oxoguanine DNA glycosylase, N-terminal domain MutS_V PF00488.16 GAM26571.1 - 1.1e-95 319.5 0.1 2e-95 318.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 GAM26571.1 - 6.8e-40 135.6 0.1 2e-39 134.0 0.1 1.9 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 GAM26571.1 - 4.6e-38 131.0 2.0 8.5e-38 130.1 1.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 GAM26571.1 - 4.4e-21 74.8 1.2 1.1e-20 73.6 0.8 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 GAM26571.1 - 2.2e-14 53.6 0.0 6.6e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II Cul7 PF11515.3 GAM26571.1 - 0.18 11.7 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 RRM_2 PF04059.7 GAM26572.1 - 3.2e-32 110.3 0.5 1.1e-31 108.6 0.4 1.9 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 GAM26572.1 - 1.2e-30 104.9 0.1 2.5e-13 49.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM26572.1 - 1.3e-19 69.9 0.2 1.1e-05 25.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM26572.1 - 7.3e-17 60.9 0.7 8e-09 35.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 GAM26572.1 - 1.3 8.5 13.3 2.5 7.6 9.2 1.4 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 GAM26572.1 - 1.5 7.7 5.0 2.5 6.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_12 PF13087.1 GAM26573.1 - 7.7e-60 201.7 0.0 1.9e-59 200.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM26573.1 - 3.3e-47 161.0 2.4 3.3e-47 161.0 1.7 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM26573.1 - 8.7e-13 47.8 0.2 2.2e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 GAM26573.1 - 6.6e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 GAM26573.1 - 5.3e-08 32.5 2.6 4e-05 23.0 0.0 3.2 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 GAM26573.1 - 3.8e-06 26.5 0.1 0.28 10.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 GAM26573.1 - 0.00015 21.9 0.1 0.011 15.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 GAM26573.1 - 0.00097 18.2 0.0 0.00097 18.2 0.0 2.1 3 1 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 GAM26573.1 - 0.0027 17.8 0.2 0.016 15.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 GAM26573.1 - 0.0049 16.7 1.3 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 GAM26573.1 - 0.0052 16.0 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 GAM26573.1 - 0.012 16.4 0.0 0.069 13.9 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 GAM26573.1 - 0.013 15.8 2.6 0.017 15.4 0.0 2.6 4 0 0 4 4 1 0 AAA domain AAA_25 PF13481.1 GAM26573.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 GAM26573.1 - 0.017 15.2 0.1 0.24 11.5 0.0 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 GAM26573.1 - 0.02 13.8 0.2 0.055 12.3 0.1 1.7 1 1 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.24 GAM26573.1 - 0.024 14.1 0.5 0.071 12.6 0.3 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase SR-25 PF10500.4 GAM26573.1 - 0.032 13.6 9.2 0.061 12.7 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NACHT PF05729.7 GAM26573.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 GAM26573.1 - 0.078 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 GAM26573.1 - 0.096 12.5 0.1 0.27 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAM26573.1 - 0.13 11.4 0.0 0.31 10.1 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CIA30 PF08547.7 GAM26574.1 - 2.7e-32 111.8 0.0 3.2e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.17 GAM26575.1 - 5.7e-17 61.1 0.0 9.1e-17 60.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM26575.1 - 9.3e-11 41.5 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM26575.1 - 2.3e-06 27.3 0.1 4.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 GAM26575.1 - 0.098 10.8 39.5 0.12 10.5 27.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 GAM26576.1 - 1.6e-24 86.2 42.2 2.6e-21 75.7 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 GAM26577.1 - 9e-15 55.1 0.0 1.2e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM26577.1 - 2e-09 37.3 0.0 4.7e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM26577.1 - 8.7e-09 35.2 0.1 4.7e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 GAM26577.1 - 0.0021 17.8 0.0 0.0074 16.0 0.0 1.6 1 1 0 1 1 1 1 Cutinase DUF915 PF06028.6 GAM26577.1 - 0.068 12.2 0.2 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) WD40 PF00400.27 GAM26578.1 - 1.7e-08 34.0 2.6 0.024 14.4 0.0 7.9 9 0 0 9 9 9 2 WD domain, G-beta repeat Apc3 PF12895.2 GAM26578.1 - 0.011 15.8 3.8 2 8.6 0.4 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Y_phosphatase3 PF13350.1 GAM26579.1 - 1.1e-26 94.1 0.0 1.1e-15 58.2 0.0 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 GAM26579.1 - 1.6e-08 34.5 0.0 4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 GAM26579.1 - 3.2e-05 23.3 0.0 0.00039 19.8 0.0 2.6 2 1 1 3 3 3 1 Tyrosine phosphatase family Abi_C PF14355.1 GAM26579.1 - 0.07 13.0 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Abortive infection C-terminus Pkinase_Tyr PF07714.12 GAM26581.1 - 7.7e-51 172.6 0.0 9.9e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26581.1 - 4e-47 160.5 0.0 1.5e-33 116.0 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.18 GAM26581.1 - 0.0022 17.7 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM26581.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAM26581.1 - 0.24 10.4 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAT1 PF09770.4 GAM26583.1 - 8 4.5 30.9 9.5 4.3 21.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2530 PF10745.4 GAM26584.1 - 5 7.1 8.2 6.7 6.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pro-kuma_activ PF09286.6 GAM26585.1 - 6.6e-27 94.3 0.1 7.5e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain HIT PF01230.18 GAM26585.1 - 0.02 15.3 0.3 0.037 14.5 0.2 1.3 1 0 0 1 1 1 0 HIT domain RNA_pol_Rpb1_6 PF04992.9 GAM26585.1 - 0.045 13.4 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Syntaxin-6_N PF09177.6 GAM26586.1 - 0.052 13.9 0.1 0.073 13.4 0.0 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF4634 PF15465.1 GAM26586.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) DDE_Tnp_4 PF13359.1 GAM26587.1 - 1.4e-22 79.9 0.7 5.1e-21 74.9 0.4 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM26587.1 - 1.1e-08 34.8 0.9 1.8e-08 34.2 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain Med22 PF06179.7 GAM26589.1 - 1.3e-23 83.1 11.2 1.7e-23 82.7 7.8 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.7 GAM26589.1 - 0.016 15.5 1.1 0.016 15.5 0.7 1.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Telomere_reg-2 PF10193.4 GAM26589.1 - 0.15 12.3 3.2 1.5 9.0 0.1 2.6 1 1 2 3 3 3 0 Telomere length regulation protein SR-25 PF10500.4 GAM26589.1 - 3 7.2 14.5 4.6 6.6 10.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF848 PF05852.6 GAM26589.1 - 3.6 7.4 8.0 7.5 6.3 4.9 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) AATF-Che1 PF13339.1 GAM26589.1 - 5.2 7.2 7.5 71 3.5 5.2 2.2 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4163 PF13739.1 GAM26589.1 - 9.5 7.0 10.9 7.9 7.3 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) CLU PF13236.1 GAM26590.1 - 2.4e-59 200.4 0.0 4.1e-59 199.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM26590.1 - 2e-09 37.6 0.2 2e-09 37.6 0.1 2.3 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.1 GAM26590.1 - 1.3e-07 30.9 39.4 0.16 12.1 0.2 12.8 14 1 0 14 14 14 4 Leucine Rich repeat CBFD_NFYB_HMF PF00808.18 GAM26591.1 - 4.2e-16 58.7 0.1 9e-16 57.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM26591.1 - 9.7e-06 25.6 0.3 1.4e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 YL1 PF05764.8 GAM26591.1 - 0.0055 16.3 22.7 0.0068 16.0 15.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF2457 PF10446.4 GAM26591.1 - 0.0085 14.8 22.5 0.0095 14.7 15.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CENP-T PF15511.1 GAM26591.1 - 0.014 14.6 10.9 0.015 14.5 7.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 GAM26591.1 - 0.022 12.7 27.4 0.025 12.5 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAM26591.1 - 0.031 12.3 16.2 0.03 12.3 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 GAM26591.1 - 0.063 13.3 10.1 0.068 13.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 GAM26591.1 - 0.093 11.2 18.6 0.099 11.1 12.9 1.1 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 GAM26591.1 - 0.17 10.0 12.7 0.18 10.0 8.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF572 PF04502.8 GAM26591.1 - 0.74 8.9 12.6 0.8 8.8 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3c_N PF05470.7 GAM26591.1 - 0.74 7.8 12.9 0.7 7.9 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RR_TM4-6 PF06459.7 GAM26591.1 - 0.92 9.3 8.1 1.1 9.0 5.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 GAM26591.1 - 0.94 8.8 8.2 1 8.7 5.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Ebola_NP PF05505.7 GAM26591.1 - 0.99 7.3 11.6 0.93 7.4 8.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Sporozoite_P67 PF05642.6 GAM26591.1 - 1.1 7.0 14.2 1.6 6.5 9.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Merozoite_SPAM PF07133.6 GAM26591.1 - 1.4 8.7 24.8 1.9 8.3 17.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.10 GAM26591.1 - 5.9 5.4 8.8 5.8 5.4 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Phage_CII PF05269.6 GAM26592.1 - 0.051 13.5 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage CII protein Vault PF01505.13 GAM26593.1 - 5.1e-46 154.4 0.2 1e-11 44.7 0.0 5.7 6 0 0 6 6 6 5 Major Vault Protein repeat CUE PF02845.11 GAM26594.1 - 7.2e-10 38.1 0.2 1e-06 28.1 0.1 3.9 4 0 0 4 4 4 2 CUE domain HBS1_N PF08938.5 GAM26594.1 - 0.00038 20.5 0.7 0.00038 20.5 0.5 4.5 3 2 1 4 4 4 1 HBS1 N-terminus Caldesmon PF02029.10 GAM26594.1 - 0.00055 18.4 48.6 0.00055 18.4 33.7 2.1 1 1 1 2 2 2 1 Caldesmon DUF3128 PF11326.3 GAM26594.1 - 0.082 13.0 0.2 0.082 13.0 0.2 4.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) COesterase PF00135.23 GAM26595.1 - 1.1e-124 417.1 0.0 1.2e-124 416.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM26595.1 - 2.2e-07 30.6 0.0 4.9e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM26595.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.14 GAM26596.1 - 2.5e-06 26.8 0.0 4.8e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Med6 PF04934.9 GAM26597.1 - 1.6e-38 131.4 1.1 2.4e-38 130.8 0.7 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Orthopox_A49R PF06489.6 GAM26597.1 - 0.054 13.4 0.2 0.18 11.7 0.2 1.8 1 1 1 2 2 2 0 Orthopoxvirus A49R protein Arch_ATPase PF01637.13 GAM26598.1 - 1.6e-06 27.9 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 GAM26598.1 - 3.3e-05 23.9 0.0 0.00015 21.8 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain SHOCT PF09851.4 GAM26598.1 - 0.0019 17.6 0.2 0.004 16.5 0.2 1.6 1 0 0 1 1 1 1 Short C-terminal domain AAA_22 PF13401.1 GAM26598.1 - 0.041 14.0 0.0 0.55 10.3 0.0 2.7 1 1 0 1 1 1 0 AAA domain Ank_5 PF13857.1 GAM26601.1 - 3.5e-14 52.4 0.0 8.3e-14 51.3 0.0 1.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26601.1 - 1.6e-12 47.5 0.0 2.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26601.1 - 1.1e-11 43.9 0.0 5.1e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 GAM26601.1 - 1.1e-11 44.8 0.0 1.2e-10 41.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26601.1 - 5e-11 41.7 0.0 2.5e-08 33.3 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat GTA_TIM PF13547.1 GAM26602.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 GTA TIM-barrel-like domain Myotub-related PF06602.9 GAM26603.1 - 2.3e-124 414.7 1.0 5e-124 413.6 0.7 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 GAM26603.1 - 0.00011 21.6 0.0 0.00032 20.1 0.0 1.8 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.22 GAM26603.1 - 0.00041 19.7 1.2 0.041 13.2 0.0 2.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM26603.1 - 0.0019 18.5 0.0 0.013 15.7 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.3 GAM26603.1 - 0.0041 16.8 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 DSPc PF00782.15 GAM26603.1 - 0.0083 15.7 0.0 0.028 14.0 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain BTB PF00651.26 GAM26604.1 - 2.9e-20 72.2 1.3 3.9e-18 65.4 0.0 3.5 3 1 1 4 4 4 2 BTB/POZ domain ubiquitin PF00240.18 GAM26605.1 - 1.9e-10 39.9 0.6 5.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family DUF2407_C PF13373.1 GAM26605.1 - 1.6e-06 28.0 0.2 4e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 GAM26605.1 - 1.9e-06 27.9 0.3 4.2e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 GAM26605.1 - 5.8e-05 22.6 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 GAM26605.1 - 6.1e-05 22.8 0.1 0.00019 21.2 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CBFD_NFYB_HMF PF00808.18 GAM26606.1 - 1.1e-27 95.8 1.2 1.7e-27 95.2 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM26606.1 - 0.00015 21.7 0.1 0.00024 21.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 GAM26606.1 - 0.0042 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 GAM26606.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated LRR_8 PF13855.1 GAM26607.1 - 0.0085 15.8 1.1 0.0085 15.8 0.8 5.5 3 1 1 4 4 4 2 Leucine rich repeat Med17 PF10156.4 GAM26608.1 - 3.6e-13 48.6 4.3 1e-12 47.0 2.7 2.1 1 1 0 1 1 1 1 Subunit 17 of Mediator complex KxDL PF10241.4 GAM26609.1 - 1.2e-20 73.1 3.4 1.2e-20 73.1 2.3 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein Patched PF02460.13 GAM26609.1 - 0.17 9.7 9.0 0.2 9.5 6.2 1.0 1 0 0 1 1 1 0 Patched family TMEM51 PF15345.1 GAM26609.1 - 0.62 9.7 8.3 0.75 9.4 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4045 PF13254.1 GAM26609.1 - 1.8 7.7 10.2 2 7.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 GAM26609.1 - 3.3 5.2 18.6 3.9 5.0 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Atrophin-1 PF03154.10 GAM26609.1 - 4.3 5.3 10.1 4.4 5.3 7.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family Cupin_8 PF13621.1 GAM26611.1 - 4.6e-18 65.6 1.4 7.1e-18 65.0 0.2 1.9 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 GAM26611.1 - 8.5e-17 61.4 0.1 5.4e-16 58.8 0.0 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase APH PF01636.18 GAM26611.1 - 8.5e-05 22.3 0.0 0.23 11.1 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family F-box PF00646.28 GAM26611.1 - 0.00066 19.2 0.5 0.002 17.7 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM26611.1 - 0.0018 17.9 0.1 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like DUF3011 PF11218.3 GAM26612.1 - 0.0062 16.3 0.0 0.36 10.5 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3011) COMPASS-Shg1 PF05205.7 GAM26612.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 Trep_Strep PF09605.5 GAM26612.1 - 0.53 9.9 3.9 0.09 12.4 0.2 1.6 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) zf-CCCH_2 PF14608.1 GAM26613.1 - 3.7e-19 67.9 77.4 1.7e-05 24.6 2.9 7.3 7 0 0 7 7 7 6 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 GAM26613.1 - 7.2e-08 32.4 0.2 1.2e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 GAM26613.1 - 0.0024 17.5 3.3 0.017 14.8 0.2 10.2 8 2 2 10 10 10 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NADH-u_ox-rdase PF10785.4 GAM26614.1 - 5.9e-10 39.2 0.9 8.1e-10 38.8 0.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Adaptin_binding PF10199.4 GAM26615.1 - 7.7e-13 48.8 7.2 7.7e-13 48.8 5.0 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 CS PF04969.11 GAM26616.1 - 7.4e-09 36.0 0.1 1.2e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 CS domain Asp-B-Hydro_N PF05279.6 GAM26617.1 - 0.17 11.7 4.8 0.19 11.5 3.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mitofilin PF09731.4 GAM26617.1 - 0.73 8.4 15.3 0.74 8.3 10.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.4 GAM26617.1 - 3.3 5.8 25.2 3.4 5.8 17.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 GAM26617.1 - 3.3 6.8 22.6 4.3 6.4 15.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF936 PF06075.7 GAM26617.1 - 4.6 6.0 20.6 5.1 5.9 14.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF966 PF06136.8 GAM26617.1 - 5.3 6.3 22.4 6 6.1 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF1675 PF07897.6 GAM26617.1 - 5.6 6.7 24.0 7.6 6.3 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Lipase_chap PF03280.9 GAM26618.1 - 0.034 13.6 0.1 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein HTH_19 PF12844.2 GAM26618.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Kinesin PF00225.18 GAM26619.1 - 6.7e-96 320.8 3.7 6.7e-96 320.8 2.6 2.3 2 1 0 2 2 2 2 Kinesin motor domain SAM_1 PF00536.25 GAM26620.1 - 1.4e-06 28.4 0.3 3.4e-06 27.1 0.2 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM26620.1 - 8.2e-05 22.3 0.6 0.00023 20.9 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Reductase_C PF14759.1 GAM26620.1 - 0.029 14.6 0.0 0.089 13.0 0.0 1.8 2 0 0 2 2 2 0 Reductase C-terminal VP40 PF07447.7 GAM26620.1 - 0.066 12.2 0.5 0.12 11.3 0.3 1.3 1 0 0 1 1 1 0 Matrix protein VP40 Peptidase_C1 PF00112.18 GAM26621.1 - 1e-50 172.6 5.0 1.7e-50 171.9 3.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.21 GAM26621.1 - 3.5e-12 46.9 4.1 3.5e-12 46.9 2.9 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF4106 PF13388.1 GAM26621.1 - 0.0035 16.3 9.2 0.0051 15.8 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Peptidase_C1_2 PF03051.10 GAM26621.1 - 0.0035 15.9 0.3 0.054 12.0 0.2 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Nup35_RRM_2 PF14605.1 GAM26621.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nucleo_P87 PF07267.6 GAM26621.1 - 0.0062 15.2 0.9 0.0084 14.8 0.6 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 PIH1 PF08190.7 GAM26621.1 - 0.051 13.0 5.2 0.078 12.4 3.6 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CDC27 PF09507.5 GAM26621.1 - 0.18 10.9 3.6 0.26 10.4 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PRCC PF10253.4 GAM26621.1 - 0.29 11.7 6.7 0.56 10.8 4.6 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Mucin PF01456.12 GAM26621.1 - 0.49 10.1 25.2 0.98 9.1 17.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Inhibitor_I29 PF08246.7 GAM26622.1 - 2.6e-14 53.2 0.1 5.5e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Podoplanin PF05808.6 GAM26622.1 - 0.0018 17.8 0.2 0.0029 17.1 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.15 GAM26622.1 - 0.0064 16.1 0.1 0.019 14.6 0.1 1.8 1 0 0 1 1 1 1 Syndecan domain SseB PF07179.7 GAM26622.1 - 0.024 14.4 0.3 0.059 13.1 0.2 1.6 1 0 0 1 1 1 0 SseB protein N-terminal domain Gmx_para_CXXCG PF09535.5 GAM26622.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) VSP PF03302.8 GAM26622.1 - 2.8 6.4 4.9 3.8 6.0 3.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glyco_hydro_47 PF01532.15 GAM26623.1 - 7.3e-114 380.8 1.3 8.3e-114 380.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glycos_transf_2 PF00535.21 GAM26624.1 - 1.1e-20 73.9 0.6 2.5e-20 72.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM26624.1 - 3.6e-11 43.2 0.0 6.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 GAM26624.1 - 1.9e-05 24.4 0.1 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF4573 PF15140.1 GAM26625.1 - 0.0043 16.6 11.1 0.0043 16.6 7.7 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) Isy1 PF06246.7 GAM26625.1 - 0.56 9.5 4.1 0.84 8.9 2.8 1.2 1 0 0 1 1 1 0 Isy1-like splicing family Voldacs PF03517.8 GAM26625.1 - 0.7 9.7 10.1 1.5 8.7 7.0 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Nop14 PF04147.7 GAM26625.1 - 4.8 4.9 11.3 5.7 4.7 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family FNIP PF05725.7 GAM26626.1 - 1.7e-38 130.3 24.0 7.7e-09 35.3 0.0 8.0 6 2 0 7 7 7 7 FNIP Repeat DUF4140 PF13600.1 GAM26626.1 - 0.13 12.7 0.0 0.8 10.1 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Amino_oxidase PF01593.19 GAM26627.1 - 1.3e-34 120.0 0.0 4.5e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM26627.1 - 1.8e-08 34.2 0.0 4.8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 GAM26627.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 GAM26627.1 - 0.0044 17.0 0.1 0.0099 15.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM26627.1 - 0.0084 15.1 0.4 0.013 14.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM26627.1 - 0.029 14.7 0.6 0.09 13.1 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM26627.1 - 0.13 10.7 0.9 0.24 9.8 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_47 PF01532.15 GAM26628.1 - 4.2e-143 477.2 0.4 5.2e-143 476.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3210 PF11489.3 GAM26628.1 - 1 7.9 4.8 1.5 7.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) AAT PF03417.11 GAM26629.1 - 1.9e-10 40.5 0.0 1.1e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Mad3_BUB1_I PF08311.7 GAM26631.1 - 8.8e-37 125.7 4.4 1.8e-36 124.6 3.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 GAM26631.1 - 1.8e-05 23.9 0.1 3.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26631.1 - 0.00028 20.0 0.2 0.00097 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Prim_Zn_Ribbon PF08273.7 GAM26631.1 - 0.66 10.0 4.2 32 4.6 0.7 4.4 5 0 0 5 5 5 0 Zinc-binding domain of primase-helicase Ribul_P_3_epim PF00834.14 GAM26632.1 - 1.5e-43 148.2 0.1 1.8e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.16 GAM26632.1 - 0.054 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein SNARE PF05739.14 GAM26633.1 - 0.0015 18.1 14.6 0.0023 17.6 0.5 2.9 3 1 0 3 3 3 2 SNARE domain Ribosomal_S13 PF00416.17 GAM26633.1 - 0.0095 16.3 0.4 0.024 15.1 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S13/S18 V-SNARE_C PF12352.3 GAM26633.1 - 0.061 13.4 1.5 1.2 9.2 0.4 2.6 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 GAM26633.1 - 0.17 11.6 7.0 0.57 9.9 4.9 1.8 1 0 0 1 1 1 0 Laminin Domain II Synaptobrevin PF00957.16 GAM26633.1 - 0.53 9.9 10.0 0.045 13.3 3.0 2.1 2 0 0 2 2 2 0 Synaptobrevin GST_C_3 PF14497.1 GAM26633.1 - 2.2 8.8 6.0 5.9 7.4 1.1 3.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Spore_III_AB PF09548.5 GAM26633.1 - 5.6 6.6 11.2 0.32 10.7 2.4 2.5 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PA26 PF04636.8 GAM26634.1 - 8e-73 245.6 0.0 9.2e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) EVI2A PF05399.6 GAM26634.1 - 1.1 8.4 2.9 1.5 7.9 1.2 1.7 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) IL22 PF14565.1 GAM26635.1 - 0.018 15.1 0.1 1.2e+02 2.7 0.0 5.6 3 3 4 7 7 7 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF3808 PF10300.4 GAM26636.1 - 9.9e-37 126.5 7.3 2.5e-36 125.2 5.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 GAM26636.1 - 7.6e-06 25.4 15.6 0.023 14.3 1.0 5.2 4 1 0 4 4 4 3 TPR repeat TPR_16 PF13432.1 GAM26636.1 - 1.9e-05 25.1 0.9 0.029 15.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26636.1 - 3.7e-05 23.9 12.5 0.36 11.3 0.6 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26636.1 - 0.00055 20.3 0.6 4.2 8.2 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26636.1 - 0.00066 19.9 1.4 0.19 12.0 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26636.1 - 0.0011 18.8 10.6 3.5 7.6 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26636.1 - 0.0082 15.9 14.7 11 6.1 0.6 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat BACK PF07707.10 GAM26636.1 - 0.051 13.4 0.6 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch TPR_8 PF13181.1 GAM26636.1 - 0.8 9.6 7.8 1.5 8.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps16_C PF04840.7 GAM26637.1 - 8.8e-77 258.1 4.7 1.2e-76 257.6 3.3 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 GAM26637.1 - 1.8e-50 171.6 0.4 4e-50 170.5 0.2 1.6 1 1 0 1 1 1 1 Vps16, N-terminal region Pkinase PF00069.20 GAM26638.1 - 1e-65 221.4 0.2 1.3e-65 221.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26638.1 - 4.7e-28 97.9 0.1 1.1e-27 96.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM26638.1 - 3.9e-05 22.7 0.0 9.6e-05 21.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM26638.1 - 0.0011 18.6 0.0 0.029 14.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM26638.1 - 0.0054 16.3 1.2 0.017 14.7 0.1 2.1 2 1 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 GAM26638.1 - 0.02 13.9 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FNIP PF05725.7 GAM26639.1 - 1.3e-75 249.0 32.1 1.8e-15 56.5 0.7 8.0 6 1 0 7 7 7 7 FNIP Repeat EGF_2 PF07974.8 GAM26640.1 - 0.046 13.8 14.0 0.086 13.0 9.7 1.5 1 0 0 1 1 1 0 EGF-like domain Ank_2 PF12796.2 GAM26643.1 - 8.4e-100 327.3 24.1 4.8e-20 71.6 0.2 6.9 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26643.1 - 3e-97 313.9 17.7 2.9e-10 39.4 0.1 13.4 13 0 0 13 13 13 13 Ankyrin repeat Ank_4 PF13637.1 GAM26643.1 - 2.8e-78 257.0 19.8 2.7e-11 43.6 0.0 10.8 2 1 9 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26643.1 - 5e-69 226.7 24.7 2.2e-11 43.6 0.2 9.5 3 2 7 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26643.1 - 9.6e-67 214.2 9.4 1.3e-05 24.9 0.0 13.4 13 0 0 13 13 13 13 Ankyrin repeat W2 PF02020.13 GAM26644.1 - 3.8e-19 68.4 15.0 3.8e-19 68.4 10.4 2.7 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 GAM26644.1 - 1.3e-11 44.2 0.0 9.3e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 GAM26644.1 - 4.6e-10 38.5 24.5 1.2e-05 24.5 4.1 4.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 GAM26644.1 - 0.0035 17.4 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 GAM26644.1 - 0.005 16.3 28.9 0.25 10.9 2.6 3.8 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAM26644.1 - 0.032 12.8 0.7 0.054 12.0 0.5 1.3 1 0 0 1 1 1 0 L-fucokinase EBV-NA3 PF05009.7 GAM26644.1 - 7.6 5.7 13.8 3.7 6.7 1.3 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PK PF00224.16 GAM26645.1 - 5.4e-148 492.2 9.7 7.4e-148 491.7 6.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAM26645.1 - 1.1e-27 95.8 0.4 3.3e-27 94.3 0.3 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAM26645.1 - 5.4e-05 22.1 0.7 9.7e-05 21.3 0.5 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family BRCA-2_OB1 PF09103.5 GAM26645.1 - 0.0022 17.6 0.1 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 FNIP PF05725.7 GAM26646.1 - 1.7e-56 187.8 28.3 6.7e-13 48.3 0.2 8.1 5 1 3 8 8 8 8 FNIP Repeat Phage_min_tail PF05939.8 GAM26646.1 - 0.073 13.0 0.0 5.6 6.9 0.0 3.4 3 1 1 4 4 4 0 Phage minor tail protein LRR_5 PF13306.1 GAM26646.1 - 3.6 7.2 9.4 6.3 6.5 0.5 3.3 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) AAA PF00004.24 GAM26647.1 - 2.2e-05 24.6 0.0 0.00055 20.1 0.0 2.5 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 GAM26647.1 - 0.0015 18.4 0.0 0.0049 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_35 PF14516.1 GAM26647.1 - 0.0036 15.9 0.0 0.1 11.1 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_16 PF13191.1 GAM26647.1 - 0.0096 15.9 0.0 2.4 8.0 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 GAM26647.1 - 0.065 12.9 0.0 12 5.4 0.0 2.6 1 1 1 2 2 2 0 Archaeal ATPase Zot PF05707.7 GAM26647.1 - 0.073 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PPV_E2_N PF00508.12 GAM26650.1 - 0.08 12.1 0.1 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 E2 (early) protein, N terminal DUF3447 PF11929.3 GAM26651.1 - 0.00099 18.8 0.6 0.49 10.2 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) Ank_2 PF12796.2 GAM26651.1 - 0.0071 16.6 0.2 0.74 10.1 0.2 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26651.1 - 0.026 14.7 1.2 1.7 9.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Tn7_Tnp_TnsA_C PF08721.6 GAM26651.1 - 0.054 13.5 0.2 0.43 10.6 0.0 2.4 2 1 1 3 3 3 0 TnsA endonuclease C terminal Ank PF00023.25 GAM26651.1 - 0.07 12.9 0.3 21 5.1 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.2 GAM26652.1 - 5.1e-07 29.9 0.9 0.0012 19.0 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26652.1 - 4.4e-05 23.3 3.6 3.9 7.9 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 GAM26652.1 - 0.0021 18.2 5.9 1.6 9.0 0.0 4.3 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM26652.1 - 0.0033 17.8 1.4 6.1 7.4 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) SAF_2 PF13144.1 GAM26652.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 SAF-like Ank PF00023.25 GAM26652.1 - 6.8 6.6 8.1 41 4.2 0.2 4.1 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.2 GAM26653.1 - 3.9e-15 55.9 5.9 0.0015 18.8 0.0 8.6 5 3 3 8 8 8 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26653.1 - 0.00011 22.2 3.2 11 6.4 0.0 7.4 8 1 0 8 8 8 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM26653.1 - 0.00061 20.2 7.1 15 6.2 0.0 7.5 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26653.1 - 0.00086 19.3 16.8 25 5.5 0.0 9.2 10 0 0 10 10 10 0 Ankyrin repeat Tn7_Tnp_TnsA_C PF08721.6 GAM26653.1 - 0.031 14.2 0.1 4.8 7.2 0.0 3.5 2 0 0 2 2 2 0 TnsA endonuclease C terminal Ank PF00023.25 GAM26653.1 - 0.06 13.1 13.7 7.1 6.6 0.0 7.9 10 0 0 10 10 10 0 Ankyrin repeat SKI PF01202.17 GAM26654.1 - 2.5e-17 63.2 0.0 2.8e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 GAM26654.1 - 4e-09 37.3 0.0 4.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM26654.1 - 5.8e-09 35.9 0.0 7.8e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM26654.1 - 1.6e-06 28.4 0.0 2.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 GAM26654.1 - 3.7e-05 23.4 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.1 GAM26654.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family dNK PF01712.14 GAM26654.1 - 0.065 13.1 0.3 0.17 11.8 0.2 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase DUF2075 PF09848.4 GAM26654.1 - 0.17 10.8 0.5 0.73 8.7 0.0 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 GAM26654.1 - 0.29 10.6 1.0 0.51 9.9 0.7 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_20 PF00728.17 GAM26655.1 - 7.6e-89 298.3 2.9 9.3e-89 298.0 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM26655.1 - 3.8e-20 72.8 0.4 8.9e-20 71.6 0.3 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM26655.1 - 2.2e-06 28.2 0.1 4.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.17 GAM26656.1 - 1.2e-76 258.2 0.2 1.5e-76 257.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 GAM26656.1 - 2.7e-17 63.6 0.0 5.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 GAM26656.1 - 2.2e-06 28.2 0.0 4.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pro_CA PF00484.14 GAM26657.1 - 6.6e-51 172.3 1.1 3e-49 166.9 0.0 2.3 2 0 0 2 2 2 2 Carbonic anhydrase Cas_Csy2 PF09614.5 GAM26657.1 - 0.0077 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy2) FAM220 PF15487.1 GAM26658.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 FAM220 family PH PF00169.24 GAM26659.1 - 2.6e-14 53.3 0.5 4.8e-14 52.4 0.3 1.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM26659.1 - 5.1e-08 33.1 0.9 2.6e-06 27.6 0.6 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM26659.1 - 2.5e-07 30.6 0.1 4.4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 GAM26659.1 - 3.9e-06 26.6 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 GAM26659.1 - 0.00035 20.5 0.0 0.00085 19.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM26659.1 - 0.0097 16.0 0.3 0.08 13.1 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain DEAD PF00270.24 GAM26660.1 - 4.2e-50 169.5 0.0 6.5e-49 165.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM26660.1 - 7.3e-10 38.5 0.0 1.9e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM26660.1 - 3.6e-06 26.0 0.0 5.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM26660.1 - 1.7e-05 24.7 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Histone PF00125.19 GAM26660.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Pex19 PF04614.7 GAM26661.1 - 4.3e-10 39.6 29.3 1.2e-09 38.2 9.4 2.8 2 1 0 2 2 2 2 Pex19 protein family Mucin PF01456.12 GAM26661.1 - 3 7.5 28.7 5.4 6.7 19.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MAGE_N PF12440.3 GAM26661.1 - 3.8 7.8 16.7 1.3 9.3 6.9 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal LRR_4 PF12799.2 GAM26662.1 - 5.4e-06 25.9 17.3 0.00031 20.3 0.2 5.1 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM26662.1 - 6.9e-06 25.7 14.6 1.4e-05 24.7 1.8 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 GAM26662.1 - 0.00015 21.4 22.6 0.063 13.3 0.3 6.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 GAM26662.1 - 0.088 12.8 19.1 1.4 9.2 0.1 6.7 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 GAM26662.1 - 0.32 11.3 11.3 21 5.9 0.0 6.2 6 0 0 6 6 6 0 Leucine rich repeat Acetyltransf_7 PF13508.1 GAM26664.1 - 3.6e-05 23.8 0.0 6.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM26664.1 - 0.00026 20.9 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 GAM26664.1 - 0.044 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SGT1 PF07093.6 GAM26665.1 - 0.0029 16.0 17.9 0.0039 15.6 12.4 1.2 1 0 0 1 1 1 1 SGT1 protein RhoGAP PF00620.22 GAM26666.1 - 1.8e-32 112.0 0.0 3.9e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain SR-25 PF10500.4 GAM26666.1 - 0.00082 18.9 5.6 0.00082 18.9 3.9 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med19 PF10278.4 GAM26666.1 - 0.028 14.1 10.6 0.058 13.0 7.3 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 U79_P34 PF03064.11 GAM26666.1 - 0.046 13.2 6.2 0.069 12.6 4.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RR_TM4-6 PF06459.7 GAM26666.1 - 0.11 12.3 5.0 0.22 11.3 3.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 GAM26666.1 - 0.21 11.2 18.7 0.066 12.8 10.5 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.5 GAM26666.1 - 0.3 10.8 6.6 0.5 10.1 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNase_H2-Ydr279 PF09468.5 GAM26666.1 - 0.44 9.6 9.3 0.67 9.0 6.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ank_2 PF12796.2 GAM26667.1 - 1.4e-12 47.7 8.0 0.0047 17.2 0.0 7.2 4 3 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26667.1 - 2.6e-07 30.9 4.0 2.1 8.9 0.0 7.7 5 2 2 7 7 7 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26667.1 - 8e-07 29.1 2.9 26 5.2 0.0 8.0 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26667.1 - 2.3e-05 24.1 8.3 3.7 8.0 0.1 7.8 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.25 GAM26667.1 - 1.3 8.9 15.5 41 4.2 0.0 7.4 9 0 0 9 9 9 0 Ankyrin repeat Ank_2 PF12796.2 GAM26668.1 - 3.7e-18 65.6 3.4 0.01 16.1 0.0 8.0 5 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26668.1 - 1.3e-08 34.7 5.7 7.7 6.9 0.0 8.8 7 2 2 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26668.1 - 1.1e-06 28.2 7.7 8.5 6.9 0.1 8.6 8 0 0 8 8 8 2 Ankyrin repeat Ank_4 PF13637.1 GAM26668.1 - 9.6e-06 25.9 7.6 27 5.4 0.0 8.7 7 2 2 9 9 9 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM26668.1 - 0.00034 20.2 6.7 68 3.5 0.0 8.5 9 0 0 9 9 9 0 Ankyrin repeat CBM_20 PF00686.14 GAM26669.1 - 6.4e-19 67.3 0.1 9.9e-19 66.7 0.1 1.2 1 0 0 1 1 1 1 Starch binding domain zf-RING_2 PF13639.1 GAM26669.1 - 1e-09 38.0 5.8 2.5e-09 36.8 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM26669.1 - 1.5e-09 37.6 5.9 4.1e-09 36.3 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM26669.1 - 2.6e-09 36.5 4.6 2.6e-09 36.5 3.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM26669.1 - 1.5e-08 34.1 5.0 3.2e-08 33.1 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM26669.1 - 1.9e-08 33.8 6.2 4.2e-08 32.7 4.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM26669.1 - 2.4e-08 33.5 2.1 4.8e-08 32.5 1.2 1.7 1 1 1 2 2 2 1 RING-type zinc-finger U-box PF04564.10 GAM26669.1 - 4.3e-08 33.0 0.1 8.2e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 GAM26669.1 - 4.5e-07 29.2 2.7 4.5e-07 29.2 1.9 1.7 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 GAM26669.1 - 6.4e-07 29.1 5.9 1.5e-06 27.9 4.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 GAM26669.1 - 3.3e-05 23.8 1.6 3.3e-05 23.8 1.1 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 GAM26669.1 - 8.6e-05 22.0 1.9 0.00022 20.7 1.3 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 GAM26669.1 - 0.006 16.3 2.3 0.012 15.4 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-P11 PF03854.9 GAM26669.1 - 0.0064 15.9 3.3 0.0064 15.9 2.3 2.0 2 0 0 2 2 2 1 P-11 zinc finger DUF1644 PF07800.7 GAM26669.1 - 0.057 13.2 2.0 0.14 12.0 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DUF1272 PF06906.6 GAM26669.1 - 0.42 10.4 4.8 0.55 10.1 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 GAM26669.1 - 5.4 6.6 7.5 23 4.6 5.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 GAM26669.1 - 6.8 6.6 7.7 17 5.3 1.0 2.5 1 1 1 2 2 2 0 IBR domain Dynamin_N PF00350.18 GAM26670.1 - 1.6e-26 93.1 4.5 9.4e-13 48.3 0.1 3.5 3 1 1 4 4 4 2 Dynamin family MMR_HSR1 PF01926.18 GAM26670.1 - 1.5e-14 53.9 1.5 7.5e-14 51.6 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 GAM26670.1 - 2.2e-07 31.3 0.1 1.4e-06 28.7 0.0 2.5 2 0 0 2 2 1 1 Miro-like protein GTP_EFTU PF00009.22 GAM26670.1 - 2.4e-06 27.1 0.1 1.3e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM26670.1 - 5.5e-05 22.5 0.1 0.069 12.4 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.11 GAM26670.1 - 0.00038 19.6 1.8 0.0025 16.9 0.5 2.8 2 1 0 2 2 2 1 AIG1 family IIGP PF05049.8 GAM26670.1 - 0.00041 19.2 1.4 0.0069 15.2 0.0 2.8 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 GAM26670.1 - 0.0033 16.9 0.1 0.38 10.2 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 GAM26670.1 - 0.0033 16.8 0.1 0.028 13.8 0.0 2.4 1 1 0 1 1 1 1 Ras family IncA PF04156.9 GAM26670.1 - 0.015 14.8 0.1 0.015 14.8 0.1 3.0 3 1 0 3 3 3 0 IncA protein Phasin PF05597.6 GAM26670.1 - 0.02 14.6 5.4 1.6 8.4 0.0 3.9 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF258 PF03193.11 GAM26670.1 - 0.023 13.8 1.9 0.028 13.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 GAM26670.1 - 0.065 12.6 0.7 1.1 8.7 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family EssA PF10661.4 GAM26670.1 - 0.22 11.1 6.7 2.5 7.7 0.4 3.5 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA Ank_2 PF12796.2 GAM26672.1 - 3.4e-77 254.8 6.2 1.7e-18 66.7 0.0 5.6 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26672.1 - 3.1e-70 228.6 8.8 3.7e-08 32.7 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat RabGAP-TBC PF00566.13 GAM26672.1 - 2.1e-57 194.0 0.8 2.1e-57 194.0 0.5 2.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Ank_4 PF13637.1 GAM26672.1 - 5e-47 157.4 3.5 2.4e-11 43.8 0.2 6.9 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26672.1 - 5.1e-42 140.9 13.2 2e-08 34.2 0.1 7.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26672.1 - 1.7e-41 136.0 8.2 3.8e-05 23.5 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat PAT1 PF09770.4 GAM26673.1 - 0.0025 16.1 17.4 0.0028 15.9 12.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ank_2 PF12796.2 GAM26674.1 - 1.1e-50 169.8 32.3 7.5e-09 35.8 0.1 7.4 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26674.1 - 2.4e-39 133.0 17.7 5.1e-05 23.6 0.0 11.1 6 3 7 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM26674.1 - 2.6e-36 122.7 27.5 0.011 15.9 0.0 15.6 4 4 13 17 17 17 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26674.1 - 2.1e-29 98.6 18.0 0.59 10.5 0.0 16.2 13 3 4 17 17 17 8 Ankyrin repeat Ank PF00023.25 GAM26674.1 - 1.1e-23 81.7 21.5 0.22 11.4 0.0 15.6 15 1 1 16 16 16 8 Ankyrin repeat DUF1906 PF08924.6 GAM26674.1 - 0.011 15.6 0.1 20 5.0 0.0 4.4 3 2 0 4 4 4 0 Domain of unknown function (DUF1906) DUF2462 PF09495.5 GAM26674.1 - 0.083 13.6 0.0 2.2e+02 2.6 0.0 5.8 9 1 1 10 10 10 0 Protein of unknown function (DUF2462) 7tm_2 PF00002.19 GAM26675.1 - 1.5e-13 50.4 17.0 2e-13 49.9 11.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 GAM26675.1 - 5.6e-11 42.0 16.5 5.6e-11 42.0 11.5 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.12 GAM26675.1 - 0.0075 15.1 15.6 0.054 12.2 10.8 2.1 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Git3_C PF11970.3 GAM26675.1 - 0.022 14.5 0.3 0.022 14.5 0.2 2.7 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term FNIP PF05725.7 GAM26677.1 - 7e-70 230.7 27.3 1.7e-12 47.0 0.9 9.9 6 3 3 10 10 10 9 FNIP Repeat LRR_5 PF13306.1 GAM26677.1 - 0.0013 18.3 0.0 4.1 7.1 0.0 3.5 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) PLRV_ORF5 PF01690.12 GAM26677.1 - 2.3 7.2 5.6 3.2 6.7 3.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Calpain_III PF01067.17 GAM26678.1 - 1e-71 239.3 9.7 1.4e-19 70.1 0.0 5.0 5 0 0 5 5 5 4 Calpain large subunit, domain III Pkinase PF00069.20 GAM26678.1 - 4.1e-67 226.0 0.0 1.1e-66 224.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26678.1 - 7.9e-50 169.3 0.0 1.2e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM26678.1 - 0.013 14.4 0.0 0.071 12.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Fe-ADH PF00465.14 GAM26679.1 - 3.3e-98 328.6 0.0 4e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 GAM26679.1 - 3.3e-12 46.2 1.3 7.7e-08 31.9 0.0 2.9 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase SRF-TF PF00319.13 GAM26680.1 - 6.4e-23 79.7 0.3 1.2e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) P34-Arc PF04045.9 GAM26681.1 - 1.9e-81 272.9 0.0 2.2e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ABC2_membrane PF01061.19 GAM26682.1 - 1.5e-59 200.6 45.0 5.5e-38 130.2 16.4 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 GAM26682.1 - 4.8e-50 169.4 0.0 3e-25 89.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 GAM26682.1 - 6.5e-09 35.4 0.1 0.0042 16.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 GAM26682.1 - 8.1e-09 35.8 2.5 0.048 13.6 0.0 4.7 4 1 1 5 5 4 2 AAA domain DUF258 PF03193.11 GAM26682.1 - 8.6e-08 31.5 0.1 0.0058 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 PDR_CDR PF06422.7 GAM26682.1 - 3.9e-07 29.6 3.9 3.6e-06 26.5 1.2 2.8 2 0 0 2 2 2 1 CDR ABC transporter AAA_22 PF13401.1 GAM26682.1 - 7.2e-07 29.4 0.0 0.0045 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM26682.1 - 1.4e-06 28.4 0.1 0.041 13.8 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 GAM26682.1 - 3.8e-06 26.3 0.2 0.0068 15.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arch_ATPase PF01637.13 GAM26682.1 - 2.3e-05 24.2 0.0 0.023 14.3 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase PDR_assoc PF08370.6 GAM26682.1 - 7.8e-05 22.0 1.9 0.014 14.9 0.0 3.1 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_18 PF13238.1 GAM26682.1 - 8.6e-05 22.8 0.0 0.83 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 GAM26682.1 - 9.2e-05 22.1 0.1 0.25 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain PduV-EutP PF10662.4 GAM26682.1 - 9.7e-05 21.8 0.4 0.5 9.8 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 GAM26682.1 - 0.00012 22.5 1.2 1 9.6 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.1 GAM26682.1 - 0.00014 21.7 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 GAM26682.1 - 0.00017 20.4 0.1 0.24 10.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 GAM26682.1 - 0.00024 21.9 0.1 0.62 10.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 GAM26682.1 - 0.00026 20.4 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA PF00004.24 GAM26682.1 - 0.00029 21.0 0.9 0.24 11.5 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 GAM26682.1 - 0.0005 20.0 0.7 0.6 10.0 0.2 2.4 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 GAM26682.1 - 0.0021 18.5 0.1 1 9.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_24 PF13479.1 GAM26682.1 - 0.0027 17.3 1.2 1.2 8.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAM26682.1 - 0.0034 16.4 24.8 0.0034 16.4 17.2 4.0 4 1 1 5 5 3 1 ABC-2 family transporter protein RNA_helicase PF00910.17 GAM26682.1 - 0.0046 17.1 0.0 3.3 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 GAM26682.1 - 0.0052 16.4 0.4 2.2 8.1 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 GAM26682.1 - 0.0062 16.1 0.7 0.26 10.9 0.2 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 GAM26682.1 - 0.0078 16.1 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 GAM26682.1 - 0.008 16.0 0.0 5.4 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAM26682.1 - 0.012 14.6 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin CtaG_Cox11 PF04442.9 GAM26682.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 FeoB_N PF02421.13 GAM26682.1 - 0.028 13.7 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.5 GAM26682.1 - 0.029 13.5 0.5 0.68 9.1 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.1 GAM26682.1 - 0.03 13.8 0.0 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 GAM26682.1 - 0.032 14.1 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 GAM26682.1 - 0.039 13.3 3.9 0.77 9.1 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 GAM26682.1 - 0.045 12.6 0.1 6.2 5.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein RuvB_N PF05496.7 GAM26682.1 - 0.047 12.7 0.1 6.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 GAM26682.1 - 0.097 11.5 1.0 5.1 5.8 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 GAM26682.1 - 0.12 12.0 2.5 4.9 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CoA_binding_3 PF13727.1 GAM26682.1 - 0.28 11.0 7.9 0.37 10.6 1.2 2.6 2 0 0 2 2 2 0 CoA-binding domain DNA_pol_phi PF04931.8 GAM26683.1 - 2.6e-34 118.1 22.1 6e-31 107.0 15.2 4.0 4 0 0 4 4 4 2 DNA polymerase phi ThiF PF00899.16 GAM26684.1 - 6.3e-37 126.4 0.6 1.4e-36 125.3 0.4 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 GAM26684.1 - 8.8e-29 98.9 0.1 1.6e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 GAM26684.1 - 9.9e-11 41.9 0.0 2.6e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 GAM26684.1 - 0.011 15.8 0.6 0.055 13.5 0.4 2.1 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 GAM26684.1 - 0.079 11.8 1.1 0.11 11.4 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 GAM26684.1 - 0.38 9.7 2.5 0.63 9.0 1.8 1.3 1 0 0 1 1 1 0 FAD binding domain HD PF01966.17 GAM26685.1 - 2.3e-07 30.8 0.1 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 HD domain LRR_6 PF13516.1 GAM26686.1 - 1.1e-07 31.1 8.7 2.7 8.3 0.3 6.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 GAM26686.1 - 1e-05 25.0 12.7 0.035 13.7 1.7 4.9 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 GAM26686.1 - 0.00016 21.3 0.1 0.00046 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 GAM26686.1 - 0.0046 16.9 15.2 8.6 7.0 0.0 7.1 7 1 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 GAM26686.1 - 0.014 15.3 19.5 1.9 8.8 0.0 7.0 7 1 1 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.1 GAM26686.1 - 0.18 11.5 12.4 0.74 9.6 2.9 4.1 3 2 1 4 4 4 0 Leucine rich repeat Acetyltransf_7 PF13508.1 GAM26687.1 - 1e-10 41.6 0.3 1.9e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM26687.1 - 1.2e-05 25.2 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM26687.1 - 0.00032 20.4 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 GAM26687.1 - 0.00034 20.4 0.0 0.00094 19.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM26687.1 - 0.0016 18.5 0.0 0.0054 16.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM26687.1 - 0.0085 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 GAM26687.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SecIII_SopE_N PF05364.9 GAM26687.1 - 0.06 13.1 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus EF-hand_1 PF00036.27 GAM26688.1 - 4.4e-14 50.6 0.0 1.2e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAM26688.1 - 2.5e-12 46.7 0.0 3e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM26688.1 - 5.2e-12 45.1 0.3 2.4e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM26688.1 - 1.7e-09 36.7 0.1 6.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 GAM26688.1 - 4e-05 23.4 0.0 4.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.5 GAM26688.1 - 0.00013 21.8 0.2 0.00021 21.2 0.1 1.4 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 GAM26688.1 - 0.0066 15.7 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 EF hand DDE_Tnp_IS66_C PF13817.1 GAM26688.1 - 0.091 12.7 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 IS66 C-terminal element Docking PF08990.6 GAM26688.1 - 0.1 11.8 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Erythronolide synthase docking DUF2387 PF09526.5 GAM26689.1 - 0.069 13.0 0.5 0.21 11.5 0.3 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) FNIP PF05725.7 GAM26690.1 - 1.2e-67 223.6 18.7 1.7e-12 47.1 0.1 7.3 3 1 6 9 9 9 9 FNIP Repeat EF-hand_7 PF13499.1 GAM26690.1 - 1.7e-07 31.2 3.1 0.0068 16.5 1.9 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 GAM26690.1 - 3.2e-07 29.1 8.2 0.1 11.9 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 GAM26690.1 - 1.1e-05 24.9 5.1 0.0008 18.9 1.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 GAM26690.1 - 1.4e-05 24.5 7.6 0.5 10.3 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain DUF1769 PF08588.5 GAM26690.1 - 1.6e-05 24.7 3.3 0.68 9.9 0.1 5.7 4 2 1 5 5 5 1 Protein of unknown function (DUF1769) UBA PF00627.26 GAM26690.1 - 0.0078 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain COPI_C PF06957.6 GAM26690.1 - 1.7 7.1 7.6 0.92 7.9 1.4 2.1 1 1 1 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus EF-hand_5 PF13202.1 GAM26690.1 - 8.6 5.8 14.0 2.4 7.6 0.4 4.3 4 0 0 4 4 4 0 EF hand Hexapep PF00132.19 GAM26691.1 - 6.9e-14 50.6 18.2 6.3e-05 22.3 1.0 4.6 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM26691.1 - 0.00053 19.4 13.4 0.16 11.5 3.4 4.1 2 1 2 4 4 4 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 GAM26691.1 - 0.13 10.7 1.5 0.39 9.2 0.1 1.9 1 1 1 2 2 2 0 L-fucokinase AA_permease_2 PF13520.1 GAM26693.1 - 1.7e-43 148.7 38.5 2.1e-43 148.4 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 GAM26693.1 - 2.5e-28 98.6 31.2 3.7e-28 98.1 21.7 1.2 1 0 0 1 1 1 1 Amino acid permease NicO PF03824.11 GAM26693.1 - 0.012 14.9 0.6 0.012 14.9 0.4 2.5 3 0 0 3 3 3 0 High-affinity nickel-transport protein TMEMspv1-c74-12 PF11044.3 GAM26693.1 - 5.2 6.6 6.0 1.3 8.6 0.6 2.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein LUC7 PF03194.10 GAM26694.1 - 7.6e-54 182.9 12.4 1.1e-53 182.3 8.6 1.2 1 0 0 1 1 1 1 LUC7 N_terminus GFA PF04828.9 GAM26694.1 - 0.0032 17.3 0.2 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF3930 PF13067.1 GAM26694.1 - 0.2 11.5 0.5 0.37 10.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) DUF3246 PF11596.3 GAM26694.1 - 0.93 8.7 2.9 1.6 7.9 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TPR_19 PF14559.1 GAM26695.1 - 1.4e-08 34.9 1.7 0.0029 17.8 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM26695.1 - 7.6e-05 22.2 0.9 0.23 11.1 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 GAM26695.1 - 7.9e-05 23.2 0.4 2.2 9.0 0.4 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26695.1 - 0.00029 20.3 0.4 0.0087 15.7 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26695.1 - 0.00037 20.1 2.9 0.076 12.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26695.1 - 0.00083 19.7 1.5 15 6.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26695.1 - 0.0029 17.6 0.2 0.57 10.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM26695.1 - 0.0034 16.9 2.9 0.23 11.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26695.1 - 0.0045 16.8 1.3 0.041 13.8 0.2 2.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 GAM26695.1 - 0.0086 16.4 2.0 0.69 10.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM26695.1 - 0.29 11.0 3.8 1.9 8.5 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 GAM26696.1 - 1.4e-08 34.9 0.6 0.68 10.0 0.0 7.1 7 0 0 7 7 7 2 AAA domain AAA PF00004.24 GAM26696.1 - 1.2e-06 28.7 5.8 0.0015 18.7 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM26696.1 - 6.3e-06 25.9 0.0 2.6 7.7 0.0 5.1 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM26696.1 - 0.00019 21.4 0.4 3 7.7 0.7 3.8 3 1 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.12 GAM26696.1 - 0.00083 18.8 0.2 2.2 7.6 0.0 3.8 3 1 0 3 3 3 2 IstB-like ATP binding protein AAA_30 PF13604.1 GAM26696.1 - 0.003 17.1 0.0 2.5 7.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 GAM26696.1 - 0.023 14.4 0.2 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 GAM26696.1 - 0.055 13.0 0.3 4.6 6.8 0.1 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM26696.1 - 0.069 12.5 0.1 4.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.5 GAM26696.1 - 0.51 10.3 3.2 20 5.2 0.1 3.3 3 0 0 3 3 3 0 Zinc ribbon domain FNIP PF05725.7 GAM26697.1 - 2e-23 82.0 4.8 2.8e-09 36.7 0.0 4.9 4 1 1 5 5 5 4 FNIP Repeat DZR PF12773.2 GAM26698.1 - 0.00088 19.0 1.4 0.0015 18.2 1.0 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-RanBP PF00641.13 GAM26698.1 - 0.0011 18.0 3.1 0.0021 17.1 2.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 GAM26698.1 - 0.0012 18.0 3.5 0.0019 17.3 2.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM26698.1 - 0.016 14.6 4.5 0.027 13.9 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF2614 PF11023.3 GAM26699.1 - 7 6.4 7.2 67 3.3 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Sel1 PF08238.7 GAM26700.1 - 2.4e-30 104.2 10.1 3.9e-09 36.8 0.1 6.6 6 1 0 6 6 6 5 Sel1 repeat TPR_16 PF13432.1 GAM26700.1 - 0.0079 16.8 10.0 0.23 12.1 0.2 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Astro_capsid PF03115.9 GAM26700.1 - 1.5 7.0 10.5 2 6.5 7.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2678 PF10856.3 GAM26701.1 - 2.4e-08 33.7 0.3 3.4e-08 33.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2678) DUF2427 PF10348.4 GAM26701.1 - 0.014 14.9 1.2 0.029 13.9 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) YwiC PF14256.1 GAM26701.1 - 0.064 13.3 1.1 0.088 12.8 0.8 1.1 1 0 0 1 1 1 0 YwiC-like protein DUF4231 PF14015.1 GAM26701.1 - 0.23 11.4 0.7 0.45 10.5 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF4131 PF13567.1 GAM26701.1 - 0.3 10.4 2.8 0.48 9.8 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) RGP PF03214.8 GAM26702.1 - 0.056 12.1 0.1 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Ribosomal_L37ae PF01780.14 GAM26702.1 - 5.7 6.8 10.0 1.3 8.9 3.1 2.3 1 1 0 2 2 2 0 Ribosomal L37ae protein family Pkinase_Tyr PF07714.12 GAM26703.1 - 1.2e-68 231.0 0.0 1.5e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26703.1 - 2.1e-56 190.9 0.0 2.9e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM26703.1 - 2.2e-10 40.1 0.0 4.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 GAM26703.1 - 0.00032 20.5 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 GAM26703.1 - 0.026 13.5 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Cbl_N2 PF02761.9 GAM26703.1 - 0.069 13.2 0.1 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain DUF1270 PF06900.6 GAM26704.1 - 0.75 9.9 6.9 9.9 6.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Ras PF00071.17 GAM26707.1 - 1.7e-53 180.3 0.0 2.1e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM26707.1 - 7.8e-15 55.4 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM26707.1 - 4.4e-07 29.3 0.0 1.1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM26707.1 - 7.2e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CesA PF11439.3 GAM26707.1 - 0.055 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Gtr1_RagA PF04670.7 GAM26707.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ArfGap PF01412.13 GAM26708.1 - 7.4e-41 138.6 0.4 3.2e-40 136.5 0.3 2.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 GAM26708.1 - 1e-15 57.7 0.0 2.8e-08 33.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.24 GAM26708.1 - 1.2e-15 57.6 0.1 3.4e-15 56.1 0.1 1.9 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.1 GAM26708.1 - 8.5e-11 42.0 0.0 0.00039 20.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) BAR PF03114.13 GAM26708.1 - 1.7e-09 37.5 9.4 1.7e-09 37.5 6.5 2.1 2 0 0 2 2 2 1 BAR domain Ank_5 PF13857.1 GAM26708.1 - 5e-09 36.1 0.0 9.7e-06 25.6 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM26708.1 - 2.2e-08 33.5 0.0 0.016 15.0 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 GAM26708.1 - 0.0017 18.4 0.1 9.7 6.7 0.0 4.0 4 0 0 4 4 3 1 Ankyrin repeat PH_4 PF15404.1 GAM26708.1 - 0.0069 15.9 0.2 0.0069 15.9 0.1 3.7 4 1 1 5 5 4 1 Pleckstrin homology domain PH_11 PF15413.1 GAM26708.1 - 0.0079 16.4 0.9 0.088 13.0 0.6 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM26708.1 - 0.032 14.4 1.0 0.099 12.8 0.1 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain DUF3550 PF12070.3 GAM26710.1 - 0.00037 19.3 0.1 0.00062 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3550/UPF0682) HSP70 PF00012.15 GAM26712.1 - 3.4e-70 236.6 0.8 4.2e-63 213.2 0.4 2.2 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 GAM26712.1 - 7.9e-07 27.9 0.0 1.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 GAM26712.1 - 0.0077 16.0 0.3 0.56 10.0 0.0 2.7 3 0 0 3 3 3 1 Cell division protein FtsA PAGK PF15284.1 GAM26712.1 - 0.032 13.9 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Phage-encoded virulence factor HSP70 PF00012.15 GAM26713.1 - 8.4e-128 426.9 0.0 1.1e-127 426.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM26713.1 - 2.6e-08 32.8 0.0 2.2e-07 29.7 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein B5 PF03484.10 GAM26713.1 - 0.0036 17.0 0.0 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF3753 PF12575.3 GAM26713.1 - 0.098 12.4 1.8 0.31 10.8 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) Syja_N PF02383.13 GAM26714.1 - 1.3e-86 290.2 0.3 1.3e-86 290.2 0.2 2.2 2 0 0 2 2 2 1 SacI homology domain WYL PF13280.1 GAM26714.1 - 0.012 15.5 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 WYL domain TIG PF01833.19 GAM26715.1 - 3.3e-15 55.8 24.5 3.5e-05 23.7 0.6 6.1 6 0 0 6 6 6 4 IPT/TIG domain Lectin_C PF00059.16 GAM26715.1 - 0.00038 21.0 0.0 0.0017 19.0 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.8 GAM26715.1 - 0.00055 20.0 6.7 0.0013 18.8 4.6 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.22 GAM26715.1 - 0.034 14.1 2.5 0.12 12.3 1.7 1.9 1 0 0 1 1 1 0 EGF-like domain Kelch_4 PF13418.1 GAM26716.1 - 9.6e-36 121.3 29.9 7.8e-09 35.1 0.1 6.8 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM26716.1 - 3.8e-32 109.7 27.6 9.7e-08 31.9 0.0 7.3 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM26716.1 - 1.7e-24 85.3 13.4 8.9e-06 25.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM26716.1 - 4.3e-20 70.9 20.2 0.00013 21.9 0.1 6.8 6 1 1 7 7 7 6 Kelch motif Kelch_1 PF01344.20 GAM26716.1 - 3.5e-18 64.8 19.0 2.1e-06 27.1 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM26716.1 - 4e-11 42.2 4.9 0.18 11.6 0.0 5.8 5 0 0 5 5 5 4 Kelch motif 7TM_GPCR_Srd PF10317.4 GAM26716.1 - 0.06 12.3 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Rep-A_N PF04057.7 GAM26718.1 - 0.035 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DNA_mis_repair PF01119.14 GAM26719.1 - 1.9e-28 98.3 0.1 6.1e-28 96.6 0.1 2.0 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 GAM26719.1 - 3.1e-11 43.0 0.0 3.1e-11 43.0 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM26719.1 - 5.5e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GOLD_2 PF13897.1 GAM26719.1 - 1 9.6 4.9 0.44 10.7 0.0 2.7 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking Aminotran_1_2 PF00155.16 GAM26720.1 - 3.2e-16 59.2 0.0 2.1e-09 36.7 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.2 GAM26720.1 - 0.00031 19.4 0.0 0.057 11.9 0.0 2.1 1 1 1 2 2 2 2 Alanine-glyoxylate amino-transferase Glyco_hydro_6 PF01341.12 GAM26720.1 - 0.04 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 DegT_DnrJ_EryC1 PF01041.12 GAM26720.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_20 PF00982.16 GAM26721.1 - 1.5e-186 620.4 0.0 1.9e-186 620.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 GAM26721.1 - 5.3e-39 133.5 0.0 8.7e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 GAM26721.1 - 7.6e-06 25.4 0.6 7.3e-05 22.2 0.4 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Complex1_LYR PF05347.10 GAM26722.1 - 8.5e-08 31.8 0.1 1.6e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM26722.1 - 5e-07 29.8 0.1 9.6e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like ATP-grasp_3 PF02655.9 GAM26722.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 ATP-grasp domain DNA_pol_A_exo1 PF01612.15 GAM26723.1 - 4.9e-28 97.7 0.0 7.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF4248 PF14053.1 GAM26723.1 - 0.075 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) EFG_IV PF03764.13 GAM26724.1 - 6.4e-14 51.5 0.0 1.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU PF00009.22 GAM26724.1 - 3.8e-13 49.3 0.1 1.2e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAM26724.1 - 2.7e-10 39.9 0.0 1.2e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM26724.1 - 0.064 13.3 0.6 3.5 7.7 0.0 2.6 1 1 1 2 2 2 0 Elongation factor Tu domain 2 LRR_4 PF12799.2 GAM26725.1 - 0.013 15.1 3.9 25 4.6 0.4 5.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) ketoacyl-synt PF00109.21 GAM26726.1 - 2e-67 227.3 0.0 3.5e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM26726.1 - 4.4e-55 187.2 0.0 1.4e-54 185.6 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 GAM26726.1 - 9.9e-37 125.4 0.1 2e-36 124.4 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 GAM26726.1 - 3e-35 121.4 0.9 2e-34 118.8 0.1 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 GAM26726.1 - 1.2e-27 96.8 0.0 2.8e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 GAM26726.1 - 8.2e-25 87.6 0.0 2.2e-23 83.0 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 GAM26726.1 - 8.3e-06 25.9 0.1 2.3e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 GAM26726.1 - 0.0003 19.8 0.0 0.00064 18.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 GAM26726.1 - 0.0091 15.7 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DENN PF02141.16 GAM26728.1 - 3.9e-29 101.6 1.2 9.8e-29 100.3 0.8 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAM26728.1 - 2.7e-06 27.2 0.4 2.7e-06 27.2 0.3 3.8 4 1 0 4 4 4 1 uDENN domain DUF1117 PF06547.7 GAM26728.1 - 1 9.4 6.0 7.1 6.7 4.2 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) PWWP PF00855.12 GAM26730.1 - 7.4e-08 32.4 0.2 7.4e-08 32.4 0.1 2.6 3 0 0 3 3 3 1 PWWP domain RGS PF00615.14 GAM26731.1 - 5.5e-29 100.6 4.3 7.4e-29 100.2 3.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gly_radical PF01228.16 GAM26731.1 - 0.074 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Glycine radical DUF2244 PF10003.4 GAM26733.1 - 0.054 12.8 0.4 0.11 11.8 0.3 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) FTR_C PF02741.10 GAM26733.1 - 0.11 12.3 0.0 0.56 9.9 0.0 2.2 3 0 0 3 3 3 0 FTR, proximal lobe fn3 PF00041.16 GAM26733.1 - 1.4 9.0 7.2 3.9 7.6 0.1 3.6 3 0 0 3 3 3 0 Fibronectin type III domain RCC1 PF00415.13 GAM26734.1 - 8.7e-60 198.7 18.2 4.6e-12 45.9 0.0 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM26734.1 - 1.6e-48 161.3 28.9 3.7e-11 42.3 0.6 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.13 GAM26734.1 - 1.2e-43 149.1 1.4 2e-43 148.3 0.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.27 GAM26735.1 - 4.2e-21 73.9 0.7 8.5e-06 25.4 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 GAM26735.1 - 6.2e-06 24.7 0.5 0.0075 14.6 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 GAM26735.1 - 0.00011 22.3 0.1 2.1 8.7 0.0 4.3 5 0 0 5 5 5 1 PQQ-like domain BBS2_Mid PF14783.1 GAM26735.1 - 0.0033 17.1 0.1 0.22 11.3 0.1 2.8 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 GAM26735.1 - 0.0038 16.7 0.0 0.52 9.7 0.0 2.4 1 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 GAM26735.1 - 0.0063 14.7 0.1 0.85 7.6 0.0 2.8 2 2 0 2 2 2 2 Nucleoporin Nup120/160 BUD22 PF09073.5 GAM26735.1 - 0.03 13.4 34.6 0.045 12.8 24.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 GAM26735.1 - 0.22 9.5 28.4 0.33 8.9 19.7 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 GAM26735.1 - 0.3 10.6 30.1 0.51 9.9 20.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 GAM26735.1 - 0.84 7.4 32.7 1.1 7.0 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 GAM26735.1 - 7.1 5.7 18.6 10 5.2 12.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2201_N PF13203.1 GAM26735.1 - 8.3 5.4 9.8 13 4.8 6.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pyr_redox_2 PF07992.9 GAM26736.1 - 2.1e-41 142.0 0.9 3.8e-41 141.1 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 GAM26736.1 - 2.1e-32 111.4 0.2 4.8e-32 110.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 GAM26736.1 - 1.2e-19 70.4 7.1 3.8e-18 65.6 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM26736.1 - 6.8e-11 42.6 1.4 3.8e-08 33.6 0.5 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM26736.1 - 3e-07 29.6 10.8 0.00045 19.2 0.2 3.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 GAM26736.1 - 5.5e-06 25.7 2.2 6e-05 22.2 1.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM26736.1 - 8.6e-06 24.4 2.7 0.076 11.4 0.4 3.5 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 GAM26736.1 - 0.00037 19.4 7.7 0.00044 19.2 0.5 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 GAM26736.1 - 0.0026 17.3 0.1 0.62 9.6 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 GAM26736.1 - 0.0027 16.6 0.0 0.0046 15.9 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 GAM26736.1 - 0.0032 16.6 0.2 0.49 9.5 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 GAM26736.1 - 0.0059 16.6 2.6 0.023 14.6 1.8 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 GAM26736.1 - 0.012 14.7 1.1 0.015 14.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family XdhC_C PF13478.1 GAM26736.1 - 0.026 14.8 0.3 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.13 GAM26736.1 - 0.038 13.6 4.8 0.063 12.9 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAM26736.1 - 0.046 13.9 0.3 15 5.9 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 GAM26736.1 - 0.062 12.3 3.1 1.9 7.4 0.5 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 GAM26736.1 - 0.074 12.8 0.3 16 5.2 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 GAM26736.1 - 0.11 12.2 1.2 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 GAM26736.1 - 0.13 11.0 6.0 0.89 8.3 1.5 3.0 3 0 0 3 3 3 0 FAD binding domain Peptidase_M22 PF00814.20 GAM26738.1 - 5.2e-85 285.1 0.0 6e-85 284.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family zf-CHCC PF10276.4 GAM26739.1 - 1.7e-18 66.1 1.0 2.3e-18 65.7 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 GAM26739.1 - 0.024 14.2 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Pro_isomerase PF00160.16 GAM26740.1 - 2.4e-52 177.2 0.1 2.7e-52 177.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Metallophos PF00149.23 GAM26741.1 - 7.6e-07 28.7 1.9 1.3e-06 27.9 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IU_nuc_hydro PF01156.14 GAM26742.1 - 3.7e-73 246.4 0.4 4.4e-73 246.2 0.3 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 GAM26743.1 - 1.5e-92 310.5 0.3 1.7e-92 310.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 GAM26744.1 - 5.4e-76 255.9 0.2 6e-76 255.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 BRCT PF00533.21 GAM26745.1 - 4.8e-10 39.4 0.7 2e-09 37.4 0.1 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRM_5 PF13893.1 GAM26745.1 - 0.0012 18.6 0.2 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM26745.1 - 0.0029 17.2 0.1 0.0082 15.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTCB-BRCT PF12738.2 GAM26745.1 - 0.0031 17.3 0.0 0.0076 16.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Cpn60_TCP1 PF00118.19 GAM26746.1 - 1.7e-141 472.1 14.5 2e-141 471.9 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FA_desaturase PF00487.19 GAM26747.1 - 4.9e-22 78.5 20.4 9.6e-22 77.6 14.2 1.5 1 0 0 1 1 1 1 Fatty acid desaturase BRI3BP PF14965.1 GAM26747.1 - 0.018 14.4 0.3 0.018 14.4 0.2 1.9 2 1 0 2 2 2 0 Negative regulator of p53/TP53 Lipid_DES PF08557.5 GAM26747.1 - 0.025 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Metalloenzyme PF01676.13 GAM26748.1 - 2.6e-28 99.0 0.0 3.8e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PhosphMutase PF10143.4 GAM26748.1 - 7.6e-18 64.7 0.0 1.2e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Phosphodiest PF01663.17 GAM26748.1 - 9.3e-05 21.9 0.1 0.00025 20.4 0.1 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PhosphMutase PF10143.4 GAM26749.1 - 1.5e-26 93.1 0.2 1.8e-26 92.8 0.2 1.1 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 GAM26749.1 - 5.7e-05 22.6 0.0 5.7e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily GTP_EFTU PF00009.22 GAM26751.1 - 1.1e-56 191.3 0.0 1.5e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM26751.1 - 9.7e-27 92.9 0.0 3e-26 91.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM26751.1 - 7.1e-18 64.2 0.0 1.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM26751.1 - 3.1e-11 43.2 0.7 9.1e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAM26751.1 - 2.2e-07 30.6 0.0 5.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II DUF4347 PF14252.1 GAM26751.1 - 0.059 12.8 0.2 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) FNIP PF05725.7 GAM26752.1 - 8.1e-93 304.1 17.0 5.9e-13 48.5 0.0 8.9 5 2 4 9 9 9 9 FNIP Repeat LRR_5 PF13306.1 GAM26752.1 - 5.5e-06 26.1 1.3 0.0078 15.9 0.1 3.6 2 1 0 3 3 3 2 Leucine rich repeats (6 copies) DUF823 PF05689.6 GAM26752.1 - 0.0041 16.4 0.0 18 4.5 0.0 4.6 2 2 4 7 7 7 1 Salmonella repeat of unknown function (DUF823) Glyco_hydro_4C PF11975.3 GAM26752.1 - 0.16 11.6 0.3 85 2.8 0.0 5.0 4 2 3 7 7 7 0 Family 4 glycosyl hydrolase C-terminal domain FNIP PF05725.7 GAM26754.1 - 1.7e-63 210.3 4.4 4.9e-10 39.1 0.0 6.3 2 1 4 6 6 6 6 FNIP Repeat LRR_5 PF13306.1 GAM26754.1 - 1.7e-06 27.7 0.0 0.0064 16.2 0.0 3.6 1 1 1 3 3 3 3 Leucine rich repeats (6 copies) GTP_EFTU PF00009.22 GAM26756.1 - 1.4e-47 161.5 0.0 2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM26756.1 - 7.9e-24 83.5 0.0 2.5e-23 81.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 GAM26756.1 - 3.7e-18 65.1 0.0 9.1e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM26756.1 - 3.3e-11 43.1 0.7 8.9e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 GAM26756.1 - 7.1e-08 32.1 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II DUF2551 PF10826.3 GAM26756.1 - 0.097 12.5 0.4 4.9 7.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2551) SRPRB PF09439.5 GAM26756.1 - 0.12 11.5 0.0 0.35 10.0 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FNIP PF05725.7 GAM26758.1 - 1.1e-81 268.5 15.9 4.2e-14 52.2 0.1 7.2 6 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 GAM26758.1 - 0.0018 18.1 3.5 5.2 7.0 0.0 5.3 3 2 4 7 7 7 2 Protein of unknown function (DUF1769) 2OG-FeII_Oxy PF03171.15 GAM26759.1 - 4.9e-09 36.3 0.0 7.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM26759.1 - 1.8e-08 34.7 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM26759.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ATP-synt_J PF04911.7 GAM26760.1 - 0.048 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase j chain DNA_ligase_OB_2 PF14743.1 GAM26760.1 - 0.073 12.7 0.1 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 DNA ligase OB-like domain SNARE PF05739.14 GAM26761.1 - 2.9e-12 46.0 0.8 3.6e-12 45.7 0.6 1.1 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.6 GAM26761.1 - 0.013 13.1 0.2 0.014 12.9 0.1 1.0 1 0 0 1 1 1 0 Prominin SlyX PF04102.7 GAM26761.1 - 0.13 12.6 0.2 8.7 6.8 0.0 2.1 1 1 1 2 2 2 0 SlyX RAMP4 PF06624.7 GAM26762.1 - 6.2e-16 57.6 0.1 8e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 3-dmu-9_3-mt PF06983.8 GAM26762.1 - 0.025 14.8 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 3-demethylubiquinone-9 3-methyltransferase gpUL132 PF11359.3 GAM26762.1 - 0.1 11.9 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Glycoprotein UL132 Mit_KHE1 PF10173.4 GAM26764.1 - 8.7e-34 116.9 1.4 1.3e-33 116.4 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Zip PF02535.17 GAM26764.1 - 0.065 12.2 2.8 0.084 11.8 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_11 PF13414.1 GAM26765.1 - 3.2e-17 61.9 0.0 6.8e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM26765.1 - 1.8e-12 46.3 0.0 0.00029 20.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26765.1 - 2.8e-10 39.2 0.0 0.0032 17.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26765.1 - 0.011 15.6 0.0 0.28 11.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26765.1 - 0.065 13.9 0.0 0.3 11.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26765.1 - 0.089 13.4 0.0 0.33 11.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.3 GAM26765.1 - 0.25 10.0 0.0 0.25 10.0 0.0 2.6 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 FNIP PF05725.7 GAM26766.1 - 5.3e-13 48.6 18.5 2.4e-07 30.6 0.0 5.7 4 1 2 7 7 7 4 FNIP Repeat AAA_12 PF13087.1 GAM26767.1 - 7.6e-56 188.6 0.1 2.1e-55 187.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM26767.1 - 3.9e-53 180.4 0.0 2.2e-51 174.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain PAP_assoc PF03828.14 GAM26767.1 - 3.8e-12 45.9 0.8 3.2e-11 43.0 0.1 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase AAA_19 PF13245.1 GAM26767.1 - 8.8e-11 41.4 0.0 3.8e-10 39.3 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 GAM26767.1 - 6e-10 39.0 0.0 4.9e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 GAM26767.1 - 2.6e-07 30.4 1.2 0.017 14.6 0.0 4.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 GAM26767.1 - 2.5e-05 23.7 1.1 0.013 14.8 0.0 3.6 4 1 1 5 5 5 1 UvrD/REP helicase N-terminal domain NTP_transf_2 PF01909.18 GAM26767.1 - 9.7e-05 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.1 GAM26767.1 - 0.0028 17.6 0.4 0.0097 15.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4269) UvrD_C_2 PF13538.1 GAM26767.1 - 0.0032 17.5 0.0 0.012 15.7 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 GAM26767.1 - 0.015 15.4 0.0 0.46 10.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 GAM26767.1 - 0.023 14.1 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 GAM26767.1 - 0.044 13.4 0.0 0.26 10.9 0.0 2.4 1 1 0 1 1 1 0 Helicase DUF2075 PF09848.4 GAM26767.1 - 0.1 11.5 2.2 0.2 10.6 0.0 2.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 GAM26767.1 - 0.19 11.6 0.0 0.49 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Endonuc-BglII PF09195.6 GAM26768.1 - 0.11 11.9 1.0 3.9 6.9 0.4 2.1 2 0 0 2 2 2 0 Restriction endonuclease BglII ADAM_spacer1 PF05986.9 GAM26768.1 - 0.2 11.5 2.4 1 9.2 0.4 2.0 1 1 1 2 2 2 0 ADAM-TS Spacer 1 AAA_11 PF13086.1 GAM26769.1 - 1.5e-54 185.1 11.3 6.8e-28 97.8 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_12 PF13087.1 GAM26769.1 - 9.7e-54 181.7 0.0 3e-53 180.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 GAM26769.1 - 4.3e-13 49.2 0.0 1.4e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain PAP_assoc PF03828.14 GAM26769.1 - 1.4e-12 47.3 0.3 3.8e-12 45.9 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA_19 PF13245.1 GAM26769.1 - 2.3e-10 40.0 0.1 5.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NTP_transf_2 PF01909.18 GAM26769.1 - 3.4e-05 24.0 0.0 9.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA_22 PF13401.1 GAM26769.1 - 0.00037 20.6 0.7 0.003 17.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 GAM26769.1 - 0.00067 19.5 5.7 0.0046 16.8 0.0 3.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 GAM26769.1 - 0.012 15.2 0.0 0.059 12.9 0.0 2.2 1 1 0 1 1 1 0 Helicase AAA_16 PF13191.1 GAM26769.1 - 0.047 13.6 0.9 0.92 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 GAM26769.1 - 0.078 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 GAM26769.1 - 2.5 8.3 5.4 0.98 9.6 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Amidohydro_2 PF04909.9 GAM26770.1 - 7.4e-15 55.2 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Ank_2 PF12796.2 GAM26771.1 - 1.2e-05 25.5 0.3 0.026 14.8 0.0 3.5 2 2 2 4 4 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26771.1 - 0.00032 20.6 0.4 2.1 8.8 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Homeobox_KN PF05920.6 GAM26772.1 - 4.5e-17 61.4 1.6 1.3e-16 60.0 1.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 GAM26772.1 - 1.3e-08 34.3 0.4 5.5e-08 32.3 0.3 2.1 1 0 0 1 1 1 1 Homeobox domain TMF_DNA_bd PF12329.3 GAM26772.1 - 0.012 15.4 0.8 0.043 13.6 0.5 2.0 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Sec2p PF06428.6 GAM26772.1 - 0.16 11.8 3.8 0.32 10.8 0.0 2.7 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TOM_sub5 PF15178.1 GAM26773.1 - 3.3 7.4 5.9 7.9 6.2 4.1 1.7 1 1 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog HAD_2 PF13419.1 GAM26774.1 - 1.5e-19 70.8 0.0 2e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TBP PF00352.16 GAM26774.1 - 0.093 12.1 0.0 0.26 10.6 0.0 1.7 1 1 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) Lectin_N PF03954.9 GAM26774.1 - 0.094 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MCM PF00493.18 GAM26775.1 - 5.2e-128 426.5 0.0 3.6e-127 423.7 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 GAM26775.1 - 7.9e-20 71.5 1.7 1.2e-17 64.5 0.5 3.6 3 1 1 4 4 4 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM26775.1 - 2.1e-08 33.5 0.1 3.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 GAM26775.1 - 2.1e-06 27.4 0.0 9.5e-06 25.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 GAM26775.1 - 0.0029 17.2 0.1 0.03 13.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Phage_hub_GP28 PF11110.3 GAM26776.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Baseplate hub distal subunit LSR PF05624.9 GAM26777.1 - 8.4 6.2 10.9 19 5.0 7.5 1.5 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) WD40 PF00400.27 GAM26778.1 - 1.8e-49 163.8 37.6 1.1e-07 31.4 0.2 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat DENN PF02141.16 GAM26778.1 - 4.4e-42 143.8 4.6 1e-41 142.7 3.2 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 GAM26778.1 - 1.9e-13 50.1 0.0 5e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 GAM26778.1 - 6.7e-09 35.6 2.0 1.7e-08 34.3 1.4 1.8 1 0 0 1 1 1 1 dDENN domain SBF2 PF12335.3 GAM26778.1 - 7.1e-06 25.5 1.5 2.4e-05 23.7 1.0 1.8 1 1 0 1 1 1 1 Myotubularin protein PQQ_3 PF13570.1 GAM26778.1 - 0.045 14.0 1.6 41 4.6 0.0 4.5 5 0 0 5 5 5 0 PQQ-like domain DUF2838 PF10998.3 GAM26779.1 - 4.4e-32 110.2 9.6 4.4e-32 110.2 6.7 2.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2838) DUF4628 PF15429.1 GAM26779.1 - 0.0013 18.2 5.1 0.0013 18.2 3.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4628) NOA36 PF06524.7 GAM26779.1 - 2.9 7.0 5.9 6.1 6.0 4.1 1.5 1 0 0 1 1 1 0 NOA36 protein Kelch_6 PF13964.1 GAM26780.1 - 8.2e-06 25.7 4.0 0.16 12.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Alpha-2-MRAP_C PF06401.6 GAM26780.1 - 0.0091 15.8 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain Kelch_4 PF13418.1 GAM26780.1 - 0.018 14.7 1.2 2.1 8.1 0.0 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM26780.1 - 0.047 13.6 0.4 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Apolipoprotein PF01442.13 GAM26780.1 - 0.059 12.8 0.1 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 GAM26780.1 - 0.085 12.6 1.9 0.13 12.1 0.7 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L7Ae PF01248.21 GAM26782.1 - 1.4e-25 88.6 2.2 1.8e-25 88.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DASH_Dad1 PF08649.5 GAM26782.1 - 0.052 13.2 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad1 E2F_TDP PF02319.15 GAM26786.1 - 1.1e-08 34.4 0.3 1.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.6 GAM26786.1 - 0.09 12.5 0.1 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 CDC6, C terminal E2F_TDP PF02319.15 GAM26787.1 - 6e-16 57.7 0.0 1.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Cdc6_C PF09079.6 GAM26787.1 - 0.011 15.3 0.3 7.5 6.3 0.0 2.7 3 0 0 3 3 3 0 CDC6, C terminal TrmB PF01978.14 GAM26787.1 - 0.074 12.7 1.0 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ribosomal_L31e PF01198.14 GAM26788.1 - 2.8e-33 113.4 0.6 3.7e-33 113.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CarboxypepD_reg PF13620.1 GAM26789.1 - 1.1e-06 28.6 1.4 0.00095 19.1 0.0 3.2 2 1 0 3 3 3 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 GAM26789.1 - 2.3e-06 27.2 2.0 0.0085 15.8 0.0 3.3 2 1 1 3 3 3 2 Cna protein B-type domain DUF2012 PF09430.5 GAM26789.1 - 9.5e-05 22.2 0.1 0.13 12.0 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2012) fn3_3 PF14686.1 GAM26789.1 - 0.017 15.2 0.7 2.1 8.5 0.1 2.6 2 1 0 2 2 2 0 Polysaccharide lyase family 4, domain II Cadherin-like PF12733.2 GAM26789.1 - 0.088 13.0 1.9 0.45 10.8 1.3 2.0 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain Beta_helix PF13229.1 GAM26789.1 - 0.14 11.9 5.1 0.28 10.9 3.5 1.6 1 1 0 1 1 1 0 Right handed beta helix region CarboxypepD_reg PF13620.1 GAM26790.1 - 4.1e-11 42.7 2.6 0.036 14.1 0.0 6.0 5 2 1 6 6 6 3 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 GAM26790.1 - 3.6e-07 29.8 7.4 0.015 15.0 0.0 4.6 5 0 0 5 5 5 3 Cna protein B-type domain SARA PF11409.3 GAM26790.1 - 2.1e-05 24.3 2.7 5.3 7.0 0.0 4.6 4 0 0 4 4 4 2 Smad anchor for receptor activation (SARA) Chitin_bind_4 PF00379.18 GAM26790.1 - 0.03 14.5 1.0 2.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Insect cuticle protein EF-hand_6 PF13405.1 GAM26790.1 - 0.093 12.6 0.5 5.5 7.1 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 GAM26790.1 - 0.1 11.9 0.6 6.5 6.3 0.1 2.9 3 0 0 3 3 3 0 EF hand YoaP PF14268.1 GAM26790.1 - 0.27 10.5 5.2 29 4.0 0.1 3.9 4 0 0 4 4 4 0 YoaP-like DUF2141 PF09912.4 GAM26790.1 - 0.29 10.8 7.3 45 3.7 0.0 5.5 5 2 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2141) EF-hand_5 PF13202.1 GAM26790.1 - 1.1 8.6 3.6 13 5.2 0.1 2.8 2 0 0 2 2 2 0 EF hand CarboxypepD_reg PF13620.1 GAM26791.1 - 6.8e-12 45.2 5.8 3.5e-06 26.9 0.2 4.5 4 1 0 4 4 4 2 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 GAM26791.1 - 1e-05 25.1 5.3 0.062 13.0 0.1 3.5 3 0 0 3 3 3 2 Cna protein B-type domain Big_3 PF07523.7 GAM26791.1 - 0.16 12.0 2.2 0.65 10.1 0.1 3.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Cna_B PF05738.8 GAM26792.1 - 1.7e-05 24.4 0.5 3.1e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM26792.1 - 0.0024 17.8 0.0 0.006 16.6 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 GAM26792.1 - 0.0085 15.9 0.1 0.037 13.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2012) Y_Y_Y PF07495.8 GAM26792.1 - 0.047 13.4 0.3 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Y_Y_Y domain UPF0546 PF10639.4 GAM26794.1 - 1.8e-40 137.2 3.4 5.5e-40 135.6 2.3 1.9 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 DRIM PF07539.7 GAM26794.1 - 6.9e-25 87.1 1.2 8.5e-24 83.5 0.0 3.5 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT PF02985.17 GAM26794.1 - 3.4e-06 26.6 2.4 2.2 8.5 0.0 7.2 8 0 0 8 8 8 2 HEAT repeat EamA PF00892.15 GAM26794.1 - 0.0092 16.0 6.0 0.11 12.5 5.0 2.3 2 0 0 2 2 2 1 EamA-like transporter family HEAT_EZ PF13513.1 GAM26794.1 - 0.28 11.7 1.4 38 4.9 0.0 4.9 4 0 0 4 4 4 0 HEAT-like repeat CH PF00307.26 GAM26795.1 - 2.8e-36 123.8 4.3 2.1e-19 69.5 0.0 4.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM26795.1 - 1.5e-13 50.1 0.3 2.6e-10 39.8 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain Tropomyosin_1 PF12718.2 GAM26795.1 - 0.00018 21.3 18.1 0.00018 21.3 12.6 9.6 2 1 7 9 9 9 1 Tropomyosin like Filament PF00038.16 GAM26795.1 - 0.22 10.9 167.5 0.01 15.3 4.4 6.3 1 1 5 6 6 6 0 Intermediate filament protein Reo_sigmaC PF04582.7 GAM26795.1 - 3.8 6.6 58.8 0.11 11.6 3.3 7.0 1 1 6 8 8 8 0 Reovirus sigma C capsid protein TIG PF01833.19 GAM26798.1 - 1.7e-11 43.9 10.6 3.3e-10 39.8 0.5 5.4 4 1 1 5 5 5 4 IPT/TIG domain Fimbrial_PilY2 PF14481.1 GAM26798.1 - 0.12 11.7 1.2 0.54 9.6 0.0 2.4 2 1 0 2 2 2 0 Type 4 fimbrial biogenesis protein PilY2 Actin PF00022.14 GAM26799.1 - 4.8e-135 449.9 0.0 6.3e-135 449.5 0.0 1.1 1 0 0 1 1 1 1 Actin Ist1 PF03398.9 GAM26799.1 - 7.5e-51 171.8 0.2 1.2e-50 171.1 0.2 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Filamin PF00630.14 GAM26799.1 - 1.2e-39 134.9 3.0 7.2e-19 68.2 0.1 2.6 2 0 0 2 2 2 2 Filamin/ABP280 repeat Big_1 PF02369.11 GAM26799.1 - 0.0001 22.1 0.9 0.044 13.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 1) Neurexophilin PF06312.7 GAM26799.1 - 0.00096 18.4 3.1 0.29 10.3 0.1 2.3 2 0 0 2 2 2 2 Neurexophilin DUF2141 PF09912.4 GAM26799.1 - 0.043 13.4 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) PPC PF04151.10 GAM26799.1 - 0.063 14.2 3.5 6.9 7.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Big_3_4 PF13754.1 GAM26799.1 - 0.072 13.4 5.7 0.71 10.2 0.6 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Coiled PF05710.7 GAM26800.1 - 0.0032 17.9 7.8 0.0039 17.6 5.3 1.4 1 1 0 1 1 1 1 Coiled coil GEMIN8 PF15348.1 GAM26801.1 - 2.5e-06 27.6 10.4 3.2e-06 27.3 7.2 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Peptidase_S8 PF00082.17 GAM26801.1 - 0.026 13.6 0.8 0.033 13.3 0.6 1.2 1 0 0 1 1 1 0 Subtilase family BAF1_ABF1 PF04684.8 GAM26801.1 - 1 8.1 15.3 1.5 7.5 10.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pox_RNA_Pol_19 PF05320.7 GAM26801.1 - 2.8 7.6 8.5 4 7.1 5.9 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3048 PF11258.3 GAM26801.1 - 9.2 5.3 11.4 35 3.3 7.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3048) Glucosamine_iso PF01182.15 GAM26802.1 - 3.8e-22 78.9 0.0 4.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TPR_17 PF13431.1 GAM26803.1 - 4.6e-54 176.1 27.2 1.1e-07 31.5 0.0 9.1 8 1 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 GAM26803.1 - 7.3e-21 73.5 39.5 0.0017 17.9 0.2 8.7 8 1 1 9 9 9 8 TPR repeat TPR_14 PF13428.1 GAM26803.1 - 1e-09 38.1 10.6 3.9 8.3 0.1 7.7 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26803.1 - 0.00043 20.8 22.2 1.9 9.2 0.1 7.5 7 1 0 7 7 7 2 Tetratricopeptide repeat Ste5 PF11610.3 GAM26803.1 - 0.0026 17.2 2.4 4.4 6.9 0.0 5.9 7 0 0 7 7 7 1 Scaffold protein Ste5-Fus5 binding region TPR_19 PF14559.1 GAM26803.1 - 0.2 12.0 16.5 20 5.6 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF1155 PF06633.6 GAM26803.1 - 2.3 7.5 22.1 6.1 6.2 0.1 6.4 7 0 0 7 7 7 0 Protein of unknown function (DUF1155) PK PF00224.16 GAM26804.1 - 3.1e-123 410.8 5.0 3.1e-123 410.8 3.5 1.4 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAM26804.1 - 1.7e-29 101.7 0.3 3.7e-29 100.6 0.2 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAM26804.1 - 1e-05 24.5 0.3 1.9e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Imm20 PF15568.1 GAM26804.1 - 0.025 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 20 ABC_tran PF00005.22 GAM26805.1 - 2.6e-16 60.1 0.3 0.00019 21.7 0.0 4.3 4 0 0 4 4 4 4 ABC transporter AAA_21 PF13304.1 GAM26805.1 - 5.9e-09 36.2 7.2 0.0023 17.9 0.0 4.1 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 GAM26805.1 - 1.8e-08 33.8 0.0 0.34 10.1 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM26805.1 - 3.3e-07 29.7 1.0 0.028 13.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 GAM26805.1 - 2.5e-06 27.6 0.0 0.064 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 GAM26805.1 - 3.5e-06 26.5 0.2 0.11 11.8 0.0 3.7 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.1 GAM26805.1 - 0.00012 22.2 2.3 0.46 10.6 0.1 3.6 4 1 1 5 5 3 2 AAA domain DUF258 PF03193.11 GAM26805.1 - 0.0002 20.5 0.4 0.45 9.6 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM26805.1 - 0.00054 20.7 2.1 0.45 11.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 GAM26805.1 - 0.00098 19.0 0.0 2.3 8.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain DnaJ_CXXCXGXG PF00684.14 GAM26805.1 - 0.001 19.0 1.5 0.027 14.5 0.3 2.6 2 0 0 2 2 2 1 DnaJ central domain AAA_15 PF13175.1 GAM26805.1 - 0.0017 17.4 0.0 1.5 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain KaiC PF06745.8 GAM26805.1 - 0.002 17.3 0.0 0.23 10.5 0.0 2.5 2 0 0 2 2 2 1 KaiC MobB PF03205.9 GAM26805.1 - 0.0048 16.6 0.6 0.91 9.2 0.0 3.3 4 0 0 4 4 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 GAM26805.1 - 0.0054 16.6 0.0 7.4 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 GAM26805.1 - 0.0055 16.1 0.1 3.3 7.0 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 GAM26805.1 - 0.0069 16.6 0.9 1.8 8.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain Miro PF08477.8 GAM26805.1 - 0.0087 16.5 0.2 0.97 9.9 0.1 3.0 3 0 0 3 3 3 1 Miro-like protein APS_kinase PF01583.15 GAM26805.1 - 0.015 14.9 0.7 8.3 6.0 0.0 3.0 2 1 1 3 3 3 0 Adenylylsulphate kinase CobU PF02283.11 GAM26805.1 - 0.021 14.2 0.2 0.25 10.7 0.0 2.4 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PRK PF00485.13 GAM26805.1 - 0.023 14.2 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 GAM26805.1 - 0.026 14.0 0.0 0.09 12.2 0.0 1.9 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 GAM26805.1 - 0.064 13.4 0.1 16 5.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.7 GAM26805.1 - 0.079 12.6 0.0 5 6.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 GAM26805.1 - 0.081 13.2 0.2 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4350 PF14258.1 GAM26805.1 - 0.12 12.6 0.0 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) BCA_ABC_TP_C PF12399.3 GAM26805.1 - 0.25 11.0 0.1 0.25 11.0 0.1 1.9 2 0 0 2 2 1 0 Branched-chain amino acid ATP-binding cassette transporter IIGP PF05049.8 GAM26805.1 - 0.26 10.0 1.0 2.3 6.9 0.1 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Lar_restr_allev PF14354.1 GAM26805.1 - 0.3 11.4 1.9 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-RING_3 PF14369.1 GAM26805.1 - 3.5 7.7 9.4 22 5.1 0.1 3.3 2 1 1 3 3 3 0 zinc-finger zinc_ribbon_2 PF13240.1 GAM26805.1 - 3.7 7.1 5.6 30 4.2 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-IS66 PF13005.2 GAM26805.1 - 7.9 6.5 8.3 11 6.0 1.0 3.1 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 ABC_tran PF00005.22 GAM26806.1 - 7.1e-15 55.5 0.0 1.4e-08 35.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 GAM26806.1 - 2.3e-08 34.3 5.0 0.0054 16.7 0.1 3.3 3 0 0 3 3 3 3 AAA domain BCA_ABC_TP_C PF12399.3 GAM26806.1 - 1.6e-05 24.4 0.1 0.064 12.9 0.0 2.5 2 0 0 2 2 2 2 Branched-chain amino acid ATP-binding cassette transporter SMC_N PF02463.14 GAM26806.1 - 2.3e-05 23.7 0.0 0.0094 15.1 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 GAM26806.1 - 0.0012 18.8 0.0 0.0041 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 GAM26806.1 - 0.0021 17.7 0.0 0.0094 15.6 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 GAM26806.1 - 0.0036 16.8 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DnaJ_CXXCXGXG PF00684.14 GAM26806.1 - 0.0046 16.9 1.1 0.25 11.4 0.1 3.0 3 0 0 3 3 3 1 DnaJ central domain AAA_15 PF13175.1 GAM26806.1 - 0.0087 15.1 0.0 14 4.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 GAM26806.1 - 0.0094 16.0 0.0 0.041 14.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 GAM26806.1 - 0.025 14.4 0.1 0.12 12.2 0.0 2.2 2 1 1 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 GAM26806.1 - 0.041 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 GAM26806.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM26806.1 - 0.059 14.1 0.0 0.27 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 GAM26806.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 GAM26806.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 GAM26806.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_10 PF12846.2 GAM26806.1 - 0.18 11.2 0.0 0.6 9.4 0.0 2.0 1 1 0 1 1 1 0 AAA-like domain Sugar_tr PF00083.19 GAM26807.1 - 0.013 14.0 0.2 0.013 14.0 0.1 1.8 3 0 0 3 3 3 0 Sugar (and other) transporter VIT1 PF01988.14 GAM26807.1 - 6.8 6.1 11.1 1.7 8.0 1.7 2.5 2 0 0 2 2 2 0 VIT family tRNA-synt_1b PF00579.20 GAM26808.1 - 6.2e-51 173.2 0.0 7.3e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1 PF00133.17 GAM26809.1 - 4.8e-190 632.5 1.7 6.6e-189 628.7 1.2 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM26809.1 - 6.5e-37 126.6 0.0 1.2e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM26809.1 - 4.9e-25 88.0 1.6 1.4e-08 33.8 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 GAM26809.1 - 1.5e-10 40.6 0.2 9.3e-07 28.3 0.1 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 GAM26809.1 - 1e-06 28.6 1.3 2.8e-06 27.3 0.9 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 GAM26809.1 - 1.4e-05 24.3 0.0 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 GAM26809.1 - 0.0068 15.1 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) DUF4116 PF13475.1 GAM26810.1 - 1.9e-208 673.9 45.2 2.4e-18 65.3 0.1 15.5 10 3 7 17 17 17 17 Domain of unknown function (DUF4116) DUF1667 PF07892.6 GAM26810.1 - 4.2e-12 45.5 0.0 12 5.6 0.0 11.4 7 4 8 16 16 16 3 Protein of unknown function (DUF1667) DUF1912 PF08930.5 GAM26810.1 - 0.00063 19.7 16.1 35 4.5 0.1 8.8 7 3 2 10 10 10 0 Domain of unknown function (DUF1912) ArsR PF09824.4 GAM26810.1 - 0.12 11.7 11.5 3.7 6.8 0.1 6.3 2 1 7 10 10 10 0 ArsR transcriptional regulator GTPase_Cys_C PF12631.2 GAM26810.1 - 1.8 9.0 7.6 92 3.5 0.1 5.9 3 3 1 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Sen15 PF09631.5 GAM26810.1 - 5.6 7.2 10.6 45 4.3 0.1 6.1 3 3 1 4 4 4 0 Sen15 protein DFP PF04127.10 GAM26810.1 - 7.4 6.1 17.9 3.2 7.3 0.2 4.2 2 1 2 4 4 4 0 DNA / pantothenate metabolism flavoprotein ATP-synt_ab PF00006.20 GAM26811.1 - 2e-45 154.9 0.0 2.9e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 GAM26811.1 - 3.8e-07 30.2 0.1 8.6e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.20 GAM26812.1 - 6.2e-78 261.1 0.0 9e-78 260.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 GAM26812.1 - 4.7e-09 36.3 1.4 1.2e-08 35.0 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 GAM26812.1 - 8.1e-07 29.5 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Glyco_hydro_16 PF00722.16 GAM26812.1 - 0.092 12.0 0.1 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Bac_surface_Ag PF01103.18 GAM26814.1 - 3.4e-28 99.0 2.6 3.7e-28 98.9 1.8 1.0 1 0 0 1 1 1 1 Surface antigen OmpH PF03938.9 GAM26815.1 - 1.5e-27 96.4 1.4 1.7e-27 96.2 0.9 1.0 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Nup88 PF10168.4 GAM26815.1 - 0.0057 14.5 0.8 0.0065 14.3 0.6 1.1 1 0 0 1 1 1 1 Nuclear pore component ATP-synt_B PF00430.13 GAM26815.1 - 0.013 15.3 3.1 0.021 14.6 2.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Fzo_mitofusin PF04799.8 GAM26815.1 - 0.016 14.5 1.0 0.026 13.8 0.7 1.3 1 0 0 1 1 1 0 fzo-like conserved region GldM_N PF12081.3 GAM26815.1 - 0.027 14.0 1.5 0.043 13.3 1.1 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Methyltransf_30 PF05430.6 GAM26815.1 - 0.047 13.3 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Baculo_PEP_C PF04513.7 GAM26815.1 - 0.083 12.7 0.1 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prismane PF03063.15 GAM26815.1 - 0.098 11.0 0.2 0.11 10.8 0.1 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Cytochrom_B562 PF07361.6 GAM26815.1 - 0.11 12.8 1.6 4.2 7.8 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b562 Apolipoprotein PF01442.13 GAM26815.1 - 0.13 11.7 4.4 0.27 10.7 3.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Seryl_tRNA_N PF02403.17 GAM26815.1 - 0.55 10.2 4.1 2.1 8.3 1.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 GAM26815.1 - 1.3 8.4 7.3 2.9 7.3 5.1 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 tRNA-synt_2 PF00152.15 GAM26817.1 - 7.6e-91 304.3 0.1 8.8e-91 304.1 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 GAM26817.1 - 1.2e-07 31.1 0.7 0.00057 19.1 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 GAM26817.1 - 9e-05 22.1 0.1 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) 2-oxoacid_dh PF00198.18 GAM26818.1 - 1.1e-85 286.6 0.1 1.5e-85 286.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 GAM26818.1 - 1.2e-14 53.7 0.7 3e-14 52.4 0.2 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 GAM26818.1 - 1.9e-14 53.0 0.0 3.9e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 GAM26818.1 - 4.7e-05 22.9 0.0 0.00014 21.4 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like Transket_pyr PF02779.19 GAM26819.1 - 2.4e-47 160.6 0.1 3.6e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM26819.1 - 1.6e-37 128.1 0.1 3.4e-37 127.1 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain FMN_red PF03358.10 GAM26819.1 - 0.0023 17.4 0.0 0.053 13.0 0.0 2.4 2 0 0 2 2 2 1 NADPH-dependent FMN reductase HGTP_anticodon PF03129.15 GAM26819.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Anticodon binding domain E1_dh PF00676.15 GAM26820.1 - 6.3e-77 258.2 0.0 7.1e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 GAM26820.1 - 2.3e-06 27.2 0.3 8.4e-06 25.4 0.2 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 GAM26820.1 - 9.7e-05 21.4 0.0 0.0013 17.7 0.0 2.3 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 GAM26820.1 - 0.044 12.5 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain COX1 PF00115.15 GAM26821.1 - 1.7e-155 518.0 69.2 1.7e-155 518.0 47.9 1.7 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I Pyr_redox_2 PF07992.9 GAM26822.1 - 1e-29 103.8 0.2 1.2e-29 103.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM26822.1 - 2.7e-18 66.1 0.6 4.3e-16 59.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM26822.1 - 7.9e-10 39.1 0.0 4.7e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM26822.1 - 5.5e-06 25.5 0.0 0.018 13.9 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 GAM26822.1 - 0.00099 19.3 0.1 0.013 15.7 0.0 2.5 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 GAM26822.1 - 0.0016 17.5 0.1 0.076 12.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM26822.1 - 0.0024 16.7 3.9 0.033 13.0 0.0 3.5 4 1 1 5 5 5 1 FAD binding domain HI0933_like PF03486.9 GAM26822.1 - 0.0078 14.7 0.1 1.7 7.0 0.0 2.7 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 GAM26822.1 - 0.033 14.1 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 GAM26822.1 - 0.033 14.2 0.3 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 GAM26822.1 - 0.052 12.4 4.6 0.88 8.3 0.0 3.9 3 1 2 5 5 5 0 Glucose inhibited division protein A Thi4 PF01946.12 GAM26822.1 - 0.064 12.3 0.1 0.85 8.6 0.0 2.6 3 0 0 3 3 3 0 Thi4 family ABC_tran PF00005.22 GAM26823.1 - 7.7e-35 120.1 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM26823.1 - 5.3e-14 52.8 2.9 7.1e-09 36.0 0.3 2.1 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM26823.1 - 1.4e-05 25.1 0.3 3e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 GAM26823.1 - 7.7e-05 22.8 1.4 0.0015 18.7 1.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 GAM26823.1 - 0.00012 21.2 0.2 0.028 13.4 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM26823.1 - 0.00013 21.3 0.3 0.0012 18.1 0.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 GAM26823.1 - 0.0012 19.0 0.4 0.0059 16.8 0.3 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM26823.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 GAM26823.1 - 0.002 16.8 0.4 0.045 12.3 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_14 PF13173.1 GAM26823.1 - 0.0021 17.9 0.0 0.0068 16.2 0.0 1.9 1 1 2 3 3 3 1 AAA domain DUF258 PF03193.11 GAM26823.1 - 0.0036 16.5 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM26823.1 - 0.0048 16.3 0.0 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM26823.1 - 0.005 17.6 0.1 0.011 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM26823.1 - 0.0063 16.2 0.0 0.0078 15.9 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 GAM26823.1 - 0.0064 16.2 0.1 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 GAM26823.1 - 0.0071 16.6 0.2 0.012 15.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM26823.1 - 0.011 15.7 0.1 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM26823.1 - 0.02 14.4 0.1 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 GAM26823.1 - 0.023 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 GAM26823.1 - 0.028 13.6 0.4 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 GAM26823.1 - 0.032 13.6 0.2 0.058 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain ATP-synt_ab PF00006.20 GAM26823.1 - 0.067 12.6 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 GAM26823.1 - 0.076 12.4 0.1 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 GAM26823.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 GAM26823.1 - 0.089 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_24 PF13479.1 GAM26823.1 - 0.11 12.1 0.2 1 8.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 GAM26823.1 - 0.11 12.8 0.7 0.11 12.8 0.5 1.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 GAM26823.1 - 0.11 12.1 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Pyr_redox_2 PF07992.9 GAM26825.1 - 1.1e-23 84.1 0.0 3e-23 82.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.1 GAM26825.1 - 1.4e-21 77.1 6.7 1.5e-12 47.8 0.0 4.1 3 1 1 4 4 4 2 Apoptosis-inducing factor, mitochondrion-associated, C-term NAD_binding_9 PF13454.1 GAM26825.1 - 1.1e-08 35.0 3.9 0.0045 16.7 0.1 4.1 2 2 2 4 4 4 3 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM26825.1 - 6.5e-07 29.6 3.9 1.2e-06 28.7 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM26825.1 - 7.4e-07 29.4 0.7 0.047 13.7 0.1 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM26825.1 - 7.7e-05 21.7 0.0 0.072 11.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 GAM26825.1 - 0.00012 22.2 0.0 0.0016 18.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 GAM26825.1 - 0.00021 20.5 0.9 0.00051 19.2 0.4 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAM26825.1 - 0.00034 19.6 4.9 0.016 14.1 0.1 2.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM26825.1 - 0.0024 16.4 0.5 0.034 12.6 0.1 2.8 3 1 1 4 4 4 1 HI0933-like protein GFO_IDH_MocA PF01408.17 GAM26825.1 - 0.06 13.8 0.0 6.9 7.2 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_31 PF13847.1 GAM26826.1 - 2.3e-20 72.7 0.0 4.7e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM26826.1 - 2.9e-20 72.5 0.0 6.4e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM26826.1 - 2.6e-15 56.1 0.0 4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 GAM26826.1 - 4.6e-13 49.1 0.0 7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM26826.1 - 8.7e-12 45.3 0.3 2.5e-11 43.9 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM26826.1 - 1.1e-11 44.9 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM26826.1 - 2.3e-09 37.8 0.0 5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 GAM26826.1 - 3.4e-06 26.7 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.11 GAM26826.1 - 5.5e-06 25.4 0.8 1e-05 24.6 0.6 1.6 1 1 0 1 1 1 1 mRNA capping enzyme MetW PF07021.7 GAM26826.1 - 1e-05 24.9 0.0 2.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 GAM26826.1 - 0.00032 19.8 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 GAM26826.1 - 0.0022 17.0 0.0 0.021 13.9 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 GAM26826.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 GAM26826.1 - 0.034 12.8 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.9 GAM26826.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF2937 PF11157.3 GAM26827.1 - 0.22 10.8 1.4 0.38 10.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2718 PF10918.3 GAM26828.1 - 0.003 17.6 0.2 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2718) Ras PF00071.17 GAM26829.1 - 2.5e-56 189.5 0.1 3e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM26829.1 - 4.9e-19 68.9 0.0 7.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM26829.1 - 4.3e-13 48.8 0.1 4.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM26829.1 - 0.00089 18.4 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM26829.1 - 0.0046 16.4 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM26829.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 GAM26829.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase Cyt-b5 PF00173.23 GAM26830.1 - 3.8e-24 84.2 0.2 4.7e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AIG1 PF04548.11 GAM26831.1 - 5.3e-22 77.9 0.0 8.2e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 GAM26831.1 - 5e-10 39.3 0.0 1.2e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM26831.1 - 2.8e-05 23.3 0.1 6.8e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAM26831.1 - 0.00081 19.2 2.6 0.032 14.0 0.1 2.8 2 1 1 3 3 3 1 Dynamin family Septin PF00735.13 GAM26831.1 - 0.0013 17.8 0.2 0.0047 15.9 0.2 1.9 1 1 0 1 1 1 1 Septin AAA_16 PF13191.1 GAM26831.1 - 0.0021 18.0 0.0 0.006 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 GAM26831.1 - 0.0042 16.2 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 GAM26831.1 - 0.0054 16.0 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B T2SE PF00437.15 GAM26831.1 - 0.0093 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 GAM26831.1 - 0.015 14.2 0.0 0.051 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 GAM26831.1 - 0.026 14.0 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 GAM26831.1 - 0.027 14.7 0.2 0.073 13.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 GAM26831.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 GAM26831.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 GAM26831.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Tmemb_185A PF10269.4 GAM26832.1 - 8.4e-33 113.9 20.9 8.4e-33 113.9 14.5 2.5 1 1 2 3 3 3 2 Transmembrane Fragile-X-F protein DnaJ PF00226.26 GAM26832.1 - 4.3e-26 90.4 2.2 7.8e-26 89.6 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain EVE PF01878.13 GAM26833.1 - 1.4e-09 38.1 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 EVE domain N-Term_TEN PF11474.3 GAM26833.1 - 0.015 14.7 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain Ras_bdg_2 PF14847.1 GAM26833.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Transket_pyr PF02779.19 GAM26834.1 - 4.4e-48 163.1 0.0 7.1e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM26834.1 - 1.1e-37 128.6 0.0 1e-36 125.5 0.0 2.3 3 0 0 3 3 3 1 Transketolase, C-terminal domain Myb_DNA-binding PF00249.26 GAM26835.1 - 0.00042 20.3 0.4 0.00081 19.3 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM26835.1 - 0.01 15.9 0.2 0.01 15.9 0.2 2.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 GAM26835.1 - 0.19 11.9 0.3 0.19 11.9 0.2 2.4 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TPR_11 PF13414.1 GAM26836.1 - 2.7e-14 52.5 4.6 2.3e-07 30.3 0.1 3.3 1 1 3 4 4 4 4 TPR repeat TPR_2 PF07719.12 GAM26836.1 - 3.7e-12 45.1 6.8 0.0039 16.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26836.1 - 4e-12 46.2 0.3 0.00024 21.3 0.0 3.5 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26836.1 - 6.9e-12 44.2 9.1 0.096 12.5 0.3 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26836.1 - 7.1e-12 45.0 3.2 2.9e-05 23.9 0.0 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26836.1 - 4.1e-11 42.4 0.0 0.011 16.3 0.0 4.6 2 2 3 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26836.1 - 1.5e-09 38.2 0.0 0.00018 22.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM26836.1 - 2.1e-08 33.3 0.1 0.089 12.6 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26836.1 - 5.4e-08 32.4 1.1 1.1 9.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM26836.1 - 6.7e-07 29.3 0.5 0.042 13.9 0.1 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 GAM26836.1 - 6.5e-06 25.5 14.1 0.012 15.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.1 GAM26836.1 - 3.6e-05 23.0 3.3 5.2e-05 22.5 0.1 2.4 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 GAM26836.1 - 0.00012 22.2 1.1 1.3 9.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 GAM26836.1 - 0.0009 18.7 0.1 0.0016 17.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_15 PF13429.1 GAM26836.1 - 0.0015 17.6 0.6 0.16 10.9 1.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat FAT PF02259.18 GAM26836.1 - 0.0031 16.5 1.8 0.21 10.5 0.0 2.9 2 1 1 3 3 3 1 FAT domain ChAPs PF09295.5 GAM26836.1 - 0.0033 16.2 0.1 0.019 13.7 0.0 1.9 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 GAM26836.1 - 0.006 16.6 0.0 0.32 11.1 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM26836.1 - 0.0069 16.2 0.3 0.097 12.5 0.1 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 GAM26836.1 - 0.012 15.3 0.2 0.012 15.3 0.1 2.6 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 DUF3366 PF11846.3 GAM26836.1 - 0.043 13.6 0.0 1 9.2 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF3366) Acetyltransf_8 PF13523.1 GAM26836.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNA_pol_I_TF PF04090.7 GAM26836.1 - 0.056 12.7 0.1 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor Sel1 PF08238.7 GAM26836.1 - 0.4 11.3 11.5 1.1 9.9 0.8 4.1 5 0 0 5 5 4 0 Sel1 repeat STT3 PF02516.9 GAM26838.1 - 1.3e-120 403.6 37.9 2.3e-120 402.8 26.3 1.3 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 GAM26838.1 - 0.00026 20.9 14.8 0.00026 20.9 10.3 3.3 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GATA PF00320.22 GAM26839.1 - 1.6e-16 59.3 5.3 3.1e-16 58.4 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Rpr2 PF04032.11 GAM26839.1 - 0.54 10.1 4.2 4.7 7.1 2.9 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pirin PF02678.11 GAM26840.1 - 1.3e-36 124.6 0.1 2.4e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 GAM26840.1 - 1.3e-28 99.1 0.0 8.3e-28 96.5 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain UCH PF00443.24 GAM26841.1 - 7.6e-49 166.2 4.8 7.6e-49 166.2 3.3 4.3 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM26841.1 - 4.2e-26 92.0 1.6 4.2e-26 92.0 1.1 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase YjgF_endoribonc PF14588.1 GAM26842.1 - 6.9e-26 90.9 0.0 7.7e-26 90.7 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 GAM26842.1 - 1.4e-15 57.0 0.1 2e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP CDC73 PF05179.9 GAM26843.1 - 5.6e-55 186.6 14.0 6.7e-55 186.3 9.1 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Ecm29 PF13001.2 GAM26844.1 - 3.3e-130 434.9 9.4 9.4e-130 433.4 3.2 2.9 3 0 0 3 3 3 1 Proteasome stabiliser HEAT_2 PF13646.1 GAM26844.1 - 1.9e-11 44.1 0.3 0.053 13.8 0.0 8.1 9 1 0 9 9 9 2 HEAT repeats HEAT PF02985.17 GAM26844.1 - 2.9e-10 39.3 0.5 15 5.9 0.0 9.9 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM26844.1 - 1.5e-07 31.7 0.7 0.034 14.5 0.0 7.2 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAM26844.1 - 3.5e-07 30.5 0.4 4.8 7.7 0.0 8.2 9 1 1 10 10 10 2 HEAT-like repeat SE PF08491.5 GAM26845.1 - 7.1e-98 326.8 0.0 9e-98 326.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 GAM26845.1 - 1.2e-15 57.4 0.0 1.4e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 GAM26845.1 - 0.0016 18.3 0.3 0.0034 17.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM26845.1 - 0.0068 15.3 0.5 0.028 13.3 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.13 GAM26845.1 - 0.007 14.7 0.0 0.011 14.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Lycopene_cycl PF05834.7 GAM26845.1 - 0.02 13.8 0.6 0.27 10.0 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Reprolysin_3 PF13582.1 GAM26845.1 - 0.023 15.2 0.1 0.042 14.3 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Thi4 PF01946.12 GAM26845.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 GAM26845.1 - 0.042 12.6 2.5 0.061 12.1 1.7 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 GAM26845.1 - 0.22 11.5 0.9 0.47 10.5 0.6 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ChAPs PF09295.5 GAM26846.1 - 1.9e-46 158.6 0.7 5.5e-46 157.0 0.5 1.7 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 GAM26846.1 - 2.6e-05 24.4 0.2 0.71 10.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM26846.1 - 0.00025 20.6 0.2 0.038 13.6 0.0 3.3 2 1 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 GAM26846.1 - 0.00046 20.5 0.5 5 8.0 0.0 4.6 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26846.1 - 0.0063 16.3 0.1 16 5.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM26846.1 - 0.0094 15.0 0.1 0.026 13.6 0.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26846.1 - 0.022 15.4 0.0 1.9 9.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26846.1 - 0.1 12.8 0.1 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat VCBS PF13517.1 GAM26847.1 - 1e-20 73.8 30.9 5.1e-06 26.7 0.4 7.7 5 3 2 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 GAM26847.1 - 2.4e-19 68.4 11.1 0.0053 16.4 0.1 6.8 6 0 0 6 6 6 5 FG-GAP repeat BBS2_Mid PF14783.1 GAM26847.1 - 9e-06 25.4 1.0 0.13 12.0 0.1 5.2 6 0 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region TcdB_toxin_midN PF12256.3 GAM26847.1 - 5.3e-05 22.7 9.6 1.9 7.9 0.0 6.4 5 2 2 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region BBS2_N PF14781.1 GAM26847.1 - 0.016 14.8 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal BBS2_C PF14782.1 GAM26847.1 - 0.15 10.5 0.4 1.4 7.4 0.1 2.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, C-terminal HEAT PF02985.17 GAM26848.1 - 5.1e-15 54.1 9.0 0.029 14.4 0.1 7.9 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.1 GAM26848.1 - 1.1e-11 44.8 2.4 0.22 11.8 0.0 7.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 GAM26848.1 - 2e-05 24.9 2.5 11 6.6 0.0 6.9 6 1 1 7 7 7 1 HEAT-like repeat B56 PF01603.15 GAM26848.1 - 5.9e-05 21.8 0.6 0.023 13.2 0.0 3.3 3 0 0 3 3 3 2 Protein phosphatase 2A regulatory B subunit (B56 family) Vac14_Fab1_bd PF12755.2 GAM26848.1 - 0.0067 16.7 0.6 1.1 9.6 0.0 4.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 GAM26848.1 - 0.0069 16.3 0.5 7.9 6.5 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion IFRD PF05004.8 GAM26848.1 - 0.018 14.1 0.0 0.21 10.6 0.0 2.5 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) MVP_shoulder PF11978.3 GAM26849.1 - 8.5e-47 157.8 0.0 1.5e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 GAM26849.1 - 1.7e-27 95.1 0.0 4.8e-14 52.1 0.0 2.8 2 0 0 2 2 2 2 Major Vault Protein repeat SlyX PF04102.7 GAM26849.1 - 1.9 8.9 7.9 0.67 10.3 1.2 3.0 3 0 0 3 3 3 0 SlyX Ribosomal_L16 PF00252.13 GAM26850.1 - 1e-32 112.7 0.0 1.4e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FSH1 PF03959.8 GAM26851.1 - 7.7e-45 152.9 0.0 1.9e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF924 PF06041.6 GAM26851.1 - 1e-44 152.5 3.0 3.3e-44 150.9 2.1 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) LRR_6 PF13516.1 GAM26851.1 - 1.3e-15 55.6 12.6 0.00045 20.0 0.1 9.3 9 0 0 9 9 9 4 Leucine Rich repeat Abhydrolase_5 PF12695.2 GAM26851.1 - 9.8e-05 22.1 0.1 0.00028 20.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM26851.1 - 0.00098 19.0 0.0 0.17 11.7 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family SpoU_sub_bind PF08032.7 GAM26851.1 - 0.0059 16.7 0.5 28 4.9 0.0 4.6 6 0 0 6 6 6 0 RNA 2'-O ribose methyltransferase substrate binding Abhydrolase_1 PF00561.15 GAM26851.1 - 0.0068 15.9 1.4 0.041 13.4 0.0 3.0 4 0 0 4 4 4 1 alpha/beta hydrolase fold DLH PF01738.13 GAM26851.1 - 0.024 13.9 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAM26851.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Pribosyltran PF00156.22 GAM26852.1 - 1.2e-27 96.1 1.7 2.5e-27 95.0 1.2 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM26852.1 - 6.6e-07 28.7 0.1 1.6e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 GAM26852.1 - 5.6e-05 22.5 0.0 8.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase Mucin PF01456.12 GAM26853.1 - 0.94 9.2 44.4 0.41 10.4 23.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Mmp37 PF09139.6 GAM26853.1 - 5.4 5.9 7.9 3.4 6.5 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial matrix Mmp37 Exo5 PF09810.4 GAM26853.1 - 9.2 5.3 9.7 0.59 9.2 0.4 2.3 1 1 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease LMWPc PF01451.16 GAM26854.1 - 4.7e-24 85.2 0.0 5.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SDH_sah PF01972.11 GAM26854.1 - 0.11 11.2 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase AAA_3 PF07726.6 GAM26855.1 - 5.8e-06 25.9 0.4 1.4e-05 24.7 0.3 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 GAM26855.1 - 0.08 12.3 0.2 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SGS PF05002.10 GAM26856.1 - 1.5e-22 79.1 1.7 3.9e-22 77.7 0.8 2.0 2 0 0 2 2 1 1 SGS domain CS PF04969.11 GAM26856.1 - 1.9e-17 63.5 3.2 2e-17 63.4 1.4 1.7 2 0 0 2 2 1 1 CS domain TPR_11 PF13414.1 GAM26856.1 - 2.6e-17 62.2 0.8 1.7e-10 40.3 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 GAM26856.1 - 2.7e-16 58.3 0.1 0.00013 21.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM26856.1 - 1.4e-13 49.6 0.0 0.0041 16.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26856.1 - 8.5e-09 34.5 0.5 0.01 15.5 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26856.1 - 1.8e-06 27.6 0.1 0.017 15.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26856.1 - 3.9e-06 26.6 0.0 0.011 15.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM26856.1 - 5.9e-06 26.3 1.6 0.0085 16.2 0.6 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 GAM26856.1 - 1e-05 25.2 0.0 0.0023 17.7 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26856.1 - 1.2e-05 25.5 0.0 0.18 12.1 0.0 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26856.1 - 4.3e-05 23.7 0.0 0.18 12.4 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM26856.1 - 0.00019 21.0 0.0 0.0097 15.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26856.1 - 0.0006 20.4 0.0 0.43 11.3 0.0 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat DUF2360 PF10152.4 GAM26856.1 - 0.0067 16.7 4.1 0.017 15.4 2.8 1.7 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) NARP1 PF12569.3 GAM26856.1 - 0.045 12.5 0.0 0.045 12.5 0.0 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 GAM26856.1 - 0.12 12.8 0.0 1e+02 3.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.2 GAM26857.1 - 1.3e-15 57.5 6.1 0.00082 19.6 0.0 8.0 4 2 4 8 8 8 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26857.1 - 1.8e-08 33.8 10.3 4.6 7.7 0.0 11.2 14 0 0 14 14 14 2 Ankyrin repeat Ank_5 PF13857.1 GAM26857.1 - 6.3e-05 23.0 9.5 2.7 8.3 0.5 8.4 8 1 1 9 9 9 1 Ankyrin repeats (many copies) Fork_head PF00250.13 GAM26857.1 - 0.056 13.4 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Fork head domain MUG113 PF13455.1 GAM26857.1 - 0.094 13.1 0.7 0.46 10.9 0.0 2.5 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Ank PF00023.25 GAM26857.1 - 0.37 10.6 3.8 64 3.6 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.2 GAM26858.1 - 3.9e-06 27.0 3.3 0.085 13.2 0.0 5.1 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26858.1 - 0.012 15.8 7.0 16 6.1 0.3 7.3 9 0 0 9 9 9 0 Ankyrin repeat Ank_2 PF12796.2 GAM26859.1 - 0.07 13.4 0.0 0.27 11.5 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4339 PF14237.1 GAM26859.1 - 0.17 11.5 0.6 0.31 10.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Ank_2 PF12796.2 GAM26860.1 - 1.3e-08 35.0 0.1 0.018 15.3 0.0 4.5 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26860.1 - 0.0031 17.9 1.6 3 8.4 0.0 4.9 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26860.1 - 0.0037 17.3 2.1 3 8.3 0.0 5.6 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.25 GAM26860.1 - 0.0082 15.9 2.4 0.19 11.5 0.1 4.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 GAM26860.1 - 0.047 13.9 0.1 49 4.3 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26861.1 - 5.7e-12 45.8 4.4 0.17 12.2 0.0 7.7 4 3 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26861.1 - 4.9e-05 23.4 0.0 6.8 7.0 0.0 6.6 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26862.1 - 1.5e-13 50.8 5.2 0.0051 17.1 0.0 7.3 5 3 1 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26862.1 - 3.3e-08 32.9 1.1 0.44 10.4 0.0 6.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 GAM26862.1 - 4e-06 26.5 16.2 1.2 9.5 0.0 10.6 13 0 0 13 13 13 3 Ankyrin repeat Ank_5 PF13857.1 GAM26862.1 - 2.3e-05 24.4 1.5 5.3 7.4 0.0 6.5 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM26862.1 - 6e-05 23.4 7.8 18 6.0 0.0 9.6 10 1 1 11 11 11 1 Ankyrin repeats (many copies) Di19_C PF14571.1 GAM26863.1 - 0.054 13.7 0.1 0.054 13.7 0.1 4.1 4 0 0 4 4 4 0 Stress-induced protein Di19, C-terminal Peptidase_S28 PF05577.7 GAM26864.1 - 7.2e-110 367.5 3.0 8.7e-110 367.2 2.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 GAM26864.1 - 3.5e-06 27.0 0.0 8.6e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 GAM26864.1 - 9.9e-06 24.2 0.1 1.5e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.15 GAM26864.1 - 3.8e-05 23.3 0.1 7.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 GAM26864.1 - 0.0011 18.1 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.3 GAM26864.1 - 0.0014 17.6 0.5 0.012 14.6 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_5 PF12695.2 GAM26864.1 - 0.0018 18.0 0.1 0.0043 16.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 GAM26865.1 - 2.5e-24 85.4 0.0 3.9e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 GAM26865.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Nitrophorin PF02087.10 GAM26865.1 - 0.049 13.4 0.2 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Nitrophorin DUF676 PF05057.9 GAM26865.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Nckap1 PF09735.4 GAM26866.1 - 8e-196 652.8 5.1 1e-195 652.4 3.5 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Erf4 PF10256.4 GAM26867.1 - 3.7e-05 23.5 0.1 7e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family NDT80_PhoG PF05224.7 GAM26868.1 - 3.3e-13 50.0 0.3 3.3e-13 50.0 0.2 5.9 4 2 0 4 4 4 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 GAM26868.1 - 3.6e-13 49.4 0.0 7.3e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase VMA21 PF09446.5 GAM26868.1 - 0.0045 16.8 1.0 0.011 15.6 0.7 1.6 1 0 0 1 1 1 1 VMA21-like domain MRF_C1 PF13887.1 GAM26868.1 - 0.15 11.1 0.0 0.44 9.5 0.0 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Kelch_6 PF13964.1 GAM26870.1 - 1.8e-09 37.3 10.1 0.22 11.7 0.0 5.8 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 GAM26870.1 - 0.00037 20.2 10.2 0.094 12.5 0.0 4.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM26870.1 - 0.0022 17.6 3.4 1 9.2 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 GAM26870.1 - 0.0047 17.0 1.9 6.5 7.0 0.0 4.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM26870.1 - 0.0096 15.8 5.2 0.25 11.3 0.1 3.0 4 0 0 4 4 4 2 Kelch motif BURP PF03181.10 GAM26870.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 BURP domain Kelch_1 PF01344.20 GAM26870.1 - 0.5 9.9 6.5 24 4.5 0.0 3.8 3 0 0 3 3 3 0 Kelch motif Ank_2 PF12796.2 GAM26871.1 - 6.4e-11 42.4 2.7 0.24 11.7 0.0 8.3 5 3 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26871.1 - 0.0039 17.6 11.5 17 6.0 0.2 8.2 8 2 0 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26871.1 - 0.63 10.4 11.8 6.8 7.2 0.0 8.1 11 0 0 11 11 11 0 Ankyrin repeat CN_hydrolase PF00795.17 GAM26872.1 - 3.2e-06 26.6 0.0 0.0065 15.8 0.0 2.4 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase EVI2A PF05399.6 GAM26872.1 - 0.0056 15.9 1.4 0.045 12.9 0.0 2.2 2 0 0 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) Cons_hypoth698 PF03601.9 GAM26872.1 - 0.1 11.2 0.2 0.29 9.7 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 698 SAP30_Sin3_bdg PF13867.1 GAM26873.1 - 0.27 11.1 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 EGF_2 PF07974.8 GAM26874.1 - 0.0013 18.8 12.9 0.0026 17.8 9.0 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_alliinase PF04863.8 GAM26874.1 - 2.1 8.3 5.9 5.9 6.9 4.1 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain Herpes_capsid PF06112.6 GAM26876.1 - 4 7.4 12.0 4 7.4 8.3 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Period_C PF12114.3 GAM26876.1 - 7.6 6.0 8.2 8.2 5.9 5.7 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AhpC-TSA PF00578.16 GAM26878.1 - 3.4e-40 136.5 0.0 4.7e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM26878.1 - 3.2e-18 65.6 0.0 4.9e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 GAM26878.1 - 3.2e-12 45.8 0.0 8.3e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin TRAPPC9-Trs120 PF08626.6 GAM26879.1 - 7.4e-89 298.5 1.0 8.2e-53 179.1 0.1 3.1 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.1 GAM26879.1 - 0.091 12.4 0.2 2 8.1 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Prefoldin PF02996.12 GAM26880.1 - 5.5e-13 48.6 0.2 5.5e-13 48.6 0.2 1.4 2 0 0 2 2 2 1 Prefoldin subunit Lipoprotein_19 PF13617.1 GAM26880.1 - 0.18 11.4 0.7 12 5.5 0.0 2.2 2 0 0 2 2 2 0 YnbE-like lipoprotein Glyco_hydro_38 PF01074.17 GAM26881.1 - 1.4e-65 221.2 2.3 3.4e-65 220.0 1.6 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM26881.1 - 7.5e-26 90.9 7.5 1.3e-24 86.8 3.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM26881.1 - 2.2e-16 59.8 0.4 6.2e-16 58.3 0.2 1.9 1 0 0 1 1 1 1 Alpha mannosidase, middle domain BBS2_N PF14781.1 GAM26881.1 - 0.023 14.3 0.1 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Coiled PF05710.7 GAM26885.1 - 0.011 16.1 7.6 0.013 15.9 5.3 1.1 1 0 0 1 1 1 0 Coiled coil LIM PF00412.17 GAM26887.1 - 4.2e-11 42.7 7.3 6.1e-11 42.2 5.0 1.2 1 0 0 1 1 1 1 LIM domain C1_1 PF00130.17 GAM26887.1 - 0.51 10.1 7.6 0.5 10.1 1.6 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Kelch_6 PF13964.1 GAM26888.1 - 0.0021 18.1 4.4 4.8 7.5 0.1 3.9 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 GAM26888.1 - 0.014 14.9 5.7 0.2 11.2 0.5 3.5 3 2 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 GAM26888.1 - 0.029 14.5 0.6 8.4 6.7 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM26888.1 - 5.1 6.9 8.4 22 4.9 0.0 4.0 3 2 2 5 5 5 0 Galactose oxidase, central domain Ank_2 PF12796.2 GAM26889.1 - 8.5e-16 58.0 3.8 0.25 11.7 0.0 10.4 4 4 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26889.1 - 1.8e-08 33.8 11.1 14 6.2 0.0 12.1 14 0 0 14 14 14 2 Ankyrin repeat Ank_4 PF13637.1 GAM26889.1 - 1.2e-07 32.0 4.4 15 6.2 0.0 8.5 8 1 0 8 8 8 3 Ankyrin repeats (many copies) Spo0A_C PF08769.6 GAM26889.1 - 3.2e-05 23.7 0.2 1.5 8.7 0.0 4.6 5 0 0 5 5 5 2 Sporulation initiation factor Spo0A C terminal Glyco_hydro_18 PF00704.23 GAM26890.1 - 1.3e-23 84.0 1.6 2.2e-23 83.2 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box-like PF12937.2 GAM26891.1 - 0.006 16.2 0.0 0.018 14.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 GAM26891.1 - 0.0083 16.0 0.8 88 3.6 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.2 GAM26891.1 - 0.02 14.4 3.9 0.73 9.5 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM26891.1 - 0.037 14.0 1.0 1.2e+02 3.3 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase_Tyr PF07714.12 GAM26893.1 - 1.3e-54 184.9 0.1 1.8e-53 181.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 GAM26893.1 - 1.2e-42 145.8 0.0 2.6e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GLE1 PF07817.8 GAM26894.1 - 6.6e-50 169.4 2.9 6.6e-50 169.4 2.0 3.7 4 1 1 5 5 5 1 GLE1-like protein Ank_2 PF12796.2 GAM26895.1 - 6.8e-10 39.1 2.2 0.54 10.6 0.0 6.3 6 2 0 6 6 6 3 Ankyrin repeats (3 copies) Muskelin_N PF06588.6 GAM26895.1 - 0.0024 17.6 0.9 0.0063 16.2 0.6 1.7 1 0 0 1 1 1 1 Muskelin N-terminus Ank PF00023.25 GAM26895.1 - 0.01 15.5 0.1 52 3.9 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat Ank_3 PF13606.1 GAM26895.1 - 0.015 15.4 9.2 28 5.3 0.0 8.7 10 0 0 10 10 10 0 Ankyrin repeat Snf7 PF03357.16 GAM26895.1 - 1 8.6 4.9 4.3 6.6 0.1 2.7 3 0 0 3 3 3 0 Snf7 Ank_2 PF12796.2 GAM26896.1 - 9.1e-12 45.1 1.2 0.08 13.2 0.0 7.1 4 2 3 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26896.1 - 9.2e-05 22.8 4.7 2.6 8.6 0.1 6.8 7 1 0 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM26896.1 - 0.0005 19.7 2.8 50 3.9 0.0 7.3 8 0 0 8 8 8 0 Ankyrin repeat Ank_3 PF13606.1 GAM26896.1 - 0.001 19.1 10.7 42 4.7 0.0 9.8 12 0 0 12 12 12 0 Ankyrin repeat EBV-NA3 PF05009.7 GAM26896.1 - 0.082 12.1 0.2 0.16 11.1 0.2 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Glyco_hydro_18 PF00704.23 GAM26897.1 - 4.8e-25 88.7 1.8 7e-25 88.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.2 GAM26898.1 - 6.3e-10 39.2 6.1 0.48 10.8 0.1 5.9 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26898.1 - 3.2e-05 23.7 2.9 16 6.0 0.1 8.3 8 0 0 8 8 8 1 Ankyrin repeat Ank_5 PF13857.1 GAM26898.1 - 3.7 7.9 7.3 55 4.2 0.1 4.7 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26899.1 - 1.6e-09 37.9 0.1 0.12 12.7 0.0 4.5 3 2 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26899.1 - 3.4e-05 24.2 0.6 8.9 6.9 0.0 5.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26899.1 - 0.068 13.4 6.6 87 3.8 0.0 6.4 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.2 GAM26901.1 - 4.5e-05 23.6 0.0 0.0032 17.7 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26901.1 - 0.00015 21.8 0.3 1.1 9.6 0.0 4.5 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM26901.1 - 0.00049 20.5 0.4 0.032 14.7 0.1 3.4 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26901.1 - 0.0015 18.5 1.1 24 5.5 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat RICTOR_M PF14666.1 GAM26901.1 - 0.039 12.9 0.1 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain GlcNAc_2-epim PF07221.6 GAM26901.1 - 0.042 12.8 0.0 0.18 10.7 0.0 1.8 1 1 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Ank PF00023.25 GAM26901.1 - 0.14 12.0 0.4 4 7.4 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat zf-C3HC4_3 PF13920.1 GAM26902.1 - 1.2e-15 56.8 12.1 2e-15 56.1 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM26902.1 - 3.4e-07 30.1 14.8 6.1e-07 29.3 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM26902.1 - 6.4e-05 22.7 12.8 0.00012 21.8 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain Serglycin PF04360.7 GAM26902.1 - 0.00054 19.7 2.1 0.0011 18.6 0.7 1.9 2 0 0 2 2 2 1 Serglycin zf-P11 PF03854.9 GAM26902.1 - 0.0013 18.1 9.0 0.0035 16.7 6.2 1.7 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_5 PF14634.1 GAM26902.1 - 0.0023 17.6 11.6 0.0044 16.7 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain HTH_AraC PF00165.18 GAM26902.1 - 0.0045 16.7 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family FtsH_ext PF06480.10 GAM26902.1 - 0.74 10.0 11.1 4.4 7.5 1.5 2.5 2 0 0 2 2 2 0 FtsH Extracellular Mucin PF01456.12 GAM26902.1 - 1.4 8.6 21.8 1.4 8.7 5.5 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Period_C PF12114.3 GAM26902.1 - 3.3 7.2 9.5 0.66 9.5 2.4 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region zf-RING_4 PF14570.1 GAM26902.1 - 3.7 7.2 8.6 6.8 6.3 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3439 PF11921.3 GAM26902.1 - 8 6.2 21.9 0.41 10.4 3.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM26902.1 - 8.3 4.2 24.0 2.3 6.0 8.5 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Kelch_4 PF13418.1 GAM26903.1 - 7.1e-05 22.4 3.3 0.0029 17.3 0.0 4.2 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM26903.1 - 0.0001 22.3 6.9 0.24 11.6 0.1 4.7 4 2 1 5 5 5 2 Kelch motif Kelch_1 PF01344.20 GAM26903.1 - 0.012 15.1 1.4 0.012 15.1 1.0 4.6 6 2 1 7 7 7 0 Kelch motif Kelch_5 PF13854.1 GAM26903.1 - 1 9.3 4.5 2.1 8.3 0.1 3.4 4 0 0 4 4 4 0 Kelch motif FNIP PF05725.7 GAM26904.1 - 1.7e-71 235.8 42.3 4.8e-15 55.2 1.5 8.9 7 1 1 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 GAM26904.1 - 0.042 13.7 1.0 4.9 7.1 0.0 4.3 4 2 1 5 5 5 0 Protein of unknown function (DUF1769) ABC_tran PF00005.22 GAM26905.1 - 1.4e-33 116.0 0.0 2.3e-15 57.1 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 GAM26905.1 - 2.3e-14 52.6 6.2 5.9e-14 51.3 4.3 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 GAM26905.1 - 4.6e-12 45.6 3.6 0.00033 19.9 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM26905.1 - 2.7e-10 40.7 11.0 0.0015 18.6 0.6 4.5 3 2 1 4 4 3 3 AAA domain Fer4 PF00037.22 GAM26905.1 - 3.3e-08 32.7 2.1 3.3e-08 32.7 1.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 GAM26905.1 - 1.2e-07 31.2 0.1 1.2 8.1 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 GAM26905.1 - 4.4e-06 25.9 2.0 0.029 13.5 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM26905.1 - 9.3e-06 26.4 0.3 0.18 12.6 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 GAM26905.1 - 9.5e-06 25.8 0.0 0.049 13.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM26905.1 - 1.2e-05 25.4 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAM26905.1 - 2.9e-05 24.2 0.0 0.026 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 GAM26905.1 - 3.5e-05 23.4 11.5 3.9e-05 23.3 1.2 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.1 GAM26905.1 - 4.6e-05 22.8 0.2 0.15 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 GAM26905.1 - 4.9e-05 23.0 0.7 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 GAM26905.1 - 9.5e-05 22.3 0.0 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 GAM26905.1 - 0.0003 20.4 0.8 0.23 11.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 GAM26905.1 - 0.00031 20.2 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM26905.1 - 0.00044 20.3 0.0 0.75 9.9 0.0 3.1 3 0 0 3 3 2 1 RNA helicase Miro PF08477.8 GAM26905.1 - 0.0012 19.3 0.0 0.28 11.7 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Fer4_2 PF12797.2 GAM26905.1 - 0.0018 18.1 1.8 0.0018 18.1 1.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.17 GAM26905.1 - 0.002 17.6 3.6 0.095 12.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.10 GAM26905.1 - 0.0021 16.8 0.0 0.17 10.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 GAM26905.1 - 0.0021 18.3 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 GAM26905.1 - 0.0023 17.4 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E UPF0079 PF02367.12 GAM26905.1 - 0.0024 17.5 0.3 0.075 12.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 GAM26905.1 - 0.0025 17.6 13.0 0.0095 15.7 9.1 1.9 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.1 GAM26905.1 - 0.0039 17.1 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 GAM26905.1 - 0.0058 16.5 0.0 1.3 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 GAM26905.1 - 0.0062 16.8 2.1 0.0062 16.8 1.5 2.2 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 GAM26905.1 - 0.0097 16.6 0.2 0.0097 16.6 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Thymidylate_kin PF02223.12 GAM26905.1 - 0.012 15.0 0.1 3.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.1 GAM26905.1 - 0.014 15.0 0.8 0.23 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Fer4_10 PF13237.1 GAM26905.1 - 0.015 15.1 1.8 0.015 15.1 1.2 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain SbcCD_C PF13558.1 GAM26905.1 - 0.021 14.7 0.0 3.9 7.4 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 GAM26905.1 - 0.029 14.6 4.6 0.1 12.9 0.2 2.5 2 0 0 2 2 2 0 AAA domain Fer4_3 PF12798.2 GAM26905.1 - 0.036 14.6 4.5 0.036 14.6 3.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 GAM26905.1 - 0.043 14.0 13.9 0.12 12.6 9.6 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_10 PF12846.2 GAM26905.1 - 0.071 12.5 2.0 2.4 7.5 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 GAM26905.1 - 0.08 11.8 0.0 4.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 GAM26905.1 - 0.095 12.2 0.2 3.2 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 GAM26905.1 - 0.1 11.6 0.3 0.84 8.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 GAM26905.1 - 0.16 11.7 0.9 7.5 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 GAM26905.1 - 0.17 10.6 0.3 2.3 6.9 0.1 2.1 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 GAM26905.1 - 0.28 9.7 0.4 12 4.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 GAM26905.1 - 0.6 9.7 3.7 12 5.5 0.0 2.8 3 0 0 3 3 2 0 NTPase Fer4_8 PF13183.1 GAM26905.1 - 0.78 9.8 10.8 2.7 8.0 7.6 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Dynamin_N PF00350.18 GAM26905.1 - 0.98 9.2 3.3 5.8 6.7 0.0 3.2 4 0 0 4 4 3 0 Dynamin family NB-ARC PF00931.17 GAM26905.1 - 3.7 6.3 4.9 21 3.8 0.5 2.4 2 1 0 2 2 2 0 NB-ARC domain Fer4_4 PF12800.2 GAM26905.1 - 4.2 7.9 13.3 0.075 13.4 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L31e PF01198.14 GAM26906.1 - 6.6e-33 112.2 0.6 8.6e-33 111.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Pkinase PF00069.20 GAM26907.1 - 2.8e-10 39.8 0.0 2.8e-10 39.8 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26907.1 - 0.00011 21.3 0.0 0.00011 21.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Med15 PF09606.5 GAM26907.1 - 0.69 8.0 88.5 1 7.4 61.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal 2OG-FeII_Oxy_2 PF13532.1 GAM26908.1 - 9.2e-22 77.8 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM26908.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 GAM26908.1 - 0.0025 18.3 0.0 0.0036 17.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM26908.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CDP-OH_P_transf PF01066.16 GAM26909.1 - 3.9e-16 59.1 14.6 3.1e-15 56.3 10.2 2.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Acetyltransf_1 PF00583.19 GAM26910.1 - 6.8e-06 26.0 0.1 1.4e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM26910.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM26910.1 - 0.00026 20.9 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM26910.1 - 0.0013 18.8 0.1 0.0025 17.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM26910.1 - 0.072 12.8 0.1 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 GAM26910.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CH PF00307.26 GAM26911.1 - 6.2e-36 122.7 6.5 1.2e-19 70.3 0.1 3.8 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM26911.1 - 4.1e-13 48.7 0.3 6.5e-09 35.3 0.0 3.1 2 0 0 2 2 2 2 CAMSAP CH domain GAS PF13851.1 GAM26911.1 - 0.00056 19.1 26.4 0.00056 19.1 18.3 9.2 2 1 7 10 10 10 1 Growth-arrest specific micro-tubule binding DUF3138 PF11336.3 GAM26911.1 - 0.0021 16.2 0.6 0.0021 16.2 0.4 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF3138) BCL_N PF04714.8 GAM26911.1 - 0.49 10.0 2.9 25 4.5 0.0 4.5 4 0 0 4 4 4 0 BCL7, N-terminal conserver region DUF2296 PF10058.4 GAM26912.1 - 9.8e-17 60.4 0.4 1.8e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Hid1 PF12722.2 GAM26912.1 - 0.014 13.1 6.5 0.02 12.5 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Frag1 PF10277.4 GAM26912.1 - 0.05 13.0 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF4282 PF14110.1 GAM26913.1 - 0.0003 20.9 6.1 0.00038 20.6 4.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) SET PF00856.23 GAM26914.1 - 0.0027 18.0 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF2451 PF10474.4 GAM26914.1 - 0.057 13.1 0.1 0.072 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) TPR_11 PF13414.1 GAM26915.1 - 0.0027 17.3 0.2 0.0081 15.7 0.0 1.8 2 0 0 2 2 2 1 TPR repeat DUF3972 PF13118.1 GAM26915.1 - 0.0074 16.3 1.6 0.17 11.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3972) TPR_12 PF13424.1 GAM26915.1 - 0.012 15.5 0.3 1.8 8.5 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DDE_Tnp_4 PF13359.1 GAM26916.1 - 1.3e-27 96.3 0.0 1.4e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM26916.1 - 1.8e-11 44.0 0.4 5.3e-11 42.4 0.3 1.6 1 1 0 1 1 1 1 Transposase DDE domain Chromo PF00385.19 GAM26917.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain FG-GAP_2 PF14312.1 GAM26918.1 - 0.0037 17.2 0.3 0.57 10.2 0.1 2.9 3 0 0 3 3 3 1 FG-GAP repeat GCC2_GCC3 PF07699.8 GAM26918.1 - 0.015 14.8 5.1 0.22 11.1 3.4 2.6 1 1 0 1 1 1 0 GCC2 and GCC3 DUF4131 PF13567.1 GAM26918.1 - 0.035 13.4 0.1 0.12 11.7 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3689 PF12463.3 GAM26919.1 - 1.2e-22 80.0 5.7 5.3e-22 77.9 4.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) BTB PF00651.26 GAM26920.1 - 4e-22 78.3 1.3 3.7e-21 75.1 0.2 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 GAM26920.1 - 0.00013 21.7 0.2 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1265 PF06887.9 GAM26920.1 - 0.024 14.2 0.2 0.044 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Rsm22 PF09243.5 GAM26921.1 - 2.5e-71 239.9 0.0 6e-71 238.6 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 GAM26921.1 - 6.1e-08 32.5 0.1 2.2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM26921.1 - 0.00027 21.3 0.0 0.0074 16.7 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM26921.1 - 0.00088 19.8 0.0 0.0035 17.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM26921.1 - 0.001 19.5 0.0 0.013 15.9 0.0 3.0 4 0 0 4 4 4 1 Methyltransferase domain Glyco_hydro_38 PF01074.17 GAM26922.1 - 1.2e-71 241.2 2.4 9.2e-71 238.3 0.4 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM26922.1 - 1.1e-40 139.8 0.9 1.5e-40 139.4 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM26922.1 - 8.1e-17 61.2 0.4 6.1e-16 58.4 0.2 2.3 2 0 0 2 2 2 1 Alpha mannosidase, middle domain PH PF00169.24 GAM26923.1 - 6.5e-12 45.5 0.2 2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM26923.1 - 4.9e-05 23.5 0.3 4.9e-05 23.5 0.2 2.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 GAM26923.1 - 5.2e-05 23.0 0.0 7.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 GAM26923.1 - 5.2e-05 23.2 0.1 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM26923.1 - 0.0092 16.1 0.2 0.094 12.8 0.2 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain DUF2829 PF11195.3 GAM26923.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2829) TFIIA PF03153.8 GAM26923.1 - 0.23 11.3 8.2 0.3 10.9 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 GAM26923.1 - 0.44 9.9 12.3 0.54 9.5 8.5 1.1 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 GAM26923.1 - 1 7.4 7.0 1.1 7.2 4.8 1.1 1 0 0 1 1 1 0 Menin DNA_pol_viral_N PF00242.12 GAM26923.1 - 3.2 6.7 13.7 4.1 6.3 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 GAM26923.1 - 7.7 4.6 18.9 9.5 4.3 13.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Sarcoglycan_1 PF04790.8 GAM26924.1 - 1.2 8.2 4.6 1.8 7.6 3.2 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Ded_cyto PF06920.8 GAM26925.1 - 1.1e-27 96.4 1.8 1.2e-27 96.3 0.2 1.9 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM26925.1 - 3.9e-19 69.0 0.0 8.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.1 GAM26925.1 - 2.6e-06 26.9 0.0 5.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM26925.1 - 0.027 13.8 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SPAM PF02090.10 GAM26925.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein RPAP2_Rtr1 PF04181.8 GAM26926.1 - 1.9e-17 63.0 0.8 1.9e-17 63.0 0.6 2.0 2 0 0 2 2 2 1 Rtr1/RPAP2 family Glyco_hydro_57 PF03065.10 GAM26927.1 - 3.3e-09 36.1 0.0 9.8e-08 31.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.16 GAM26927.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Ank_2 PF12796.2 GAM26929.1 - 0.00016 21.9 0.2 0.0071 16.6 0.1 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26929.1 - 0.00026 20.9 2.2 0.0068 16.5 0.1 3.8 4 1 1 5 5 5 1 Ankyrin repeat Ank_4 PF13637.1 GAM26929.1 - 0.0011 19.4 4.3 0.38 11.3 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 GAM26929.1 - 0.0026 17.4 2.9 0.013 15.2 0.2 2.9 3 0 0 3 3 3 1 Ankyrin repeat SopA PF13981.1 GAM26930.1 - 0.03 14.3 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 SopA-like central domain Protoglobin PF11563.3 GAM26930.1 - 0.09 12.4 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Protoglobin Ank_2 PF12796.2 GAM26932.1 - 1.1e-11 44.9 0.6 0.013 15.8 0.0 7.2 5 4 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM26932.1 - 4e-07 30.3 3.1 1.6 9.3 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26933.1 - 0.0074 16.4 0.2 15 6.1 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 GAM26933.1 - 0.018 15.3 0.8 0.91 9.8 0.5 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM26933.1 - 0.041 14.2 0.3 1 9.7 0.2 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM26934.1 - 0.037 14.3 0.2 1.1 9.5 0.1 2.9 2 2 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26934.1 - 0.12 12.6 0.0 3.1 8.3 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.2 GAM26935.1 - 0.00087 19.5 0.0 0.027 14.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM26935.1 - 0.033 14.4 0.2 2.5 8.6 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.1 GAM26935.1 - 0.12 12.9 0.1 23 5.6 0.1 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF4496 PF14908.1 GAM26936.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Ank_2 PF12796.2 GAM26937.1 - 0.012 15.9 0.2 0.3 11.4 0.1 2.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) FNIP PF05725.7 GAM26938.1 - 3.7e-53 177.2 9.2 2.3e-16 59.4 0.0 6.2 4 1 2 6 6 6 6 FNIP Repeat Ank_2 PF12796.2 GAM26939.1 - 5.4e-10 39.4 11.5 0.023 15.0 0.2 6.6 4 3 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM26939.1 - 6.4e-05 22.5 5.8 3.8 7.4 0.0 7.0 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 GAM26939.1 - 0.00011 22.5 12.2 1.8 9.1 0.1 6.5 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26939.1 - 0.00047 20.1 6.1 34 5.0 0.0 7.2 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.1 GAM26939.1 - 0.0024 18.0 1.1 0.94 9.8 0.0 4.6 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26940.1 - 3.9e-07 29.6 3.9 72 4.0 0.0 10.2 11 0 0 11 11 11 0 Ankyrin repeat Ank_4 PF13637.1 GAM26940.1 - 0.0015 19.0 11.5 59 4.3 0.0 8.9 10 1 1 11 11 11 0 Ankyrin repeats (many copies) Protoglobin PF11563.3 GAM26940.1 - 0.036 13.7 0.1 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 Protoglobin FNIP PF05725.7 GAM26941.1 - 0.0027 17.6 12.9 0.91 9.5 0.2 5.7 6 1 0 6 6 6 3 FNIP Repeat CDC50 PF03381.10 GAM26942.1 - 4.3e-82 275.4 0.3 7.4e-82 274.6 0.1 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Neurensin PF14927.1 GAM26942.1 - 0.0087 15.4 0.1 3.5 7.0 0.0 2.2 2 0 0 2 2 2 2 Neurensin PIRT PF15099.1 GAM26942.1 - 0.029 13.5 0.9 0.44 9.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF3040 PF11239.3 GAM26942.1 - 0.035 14.1 1.4 0.064 13.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF1469 PF07332.6 GAM26942.1 - 0.044 13.5 0.2 3.1 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) IncA PF04156.9 GAM26942.1 - 0.051 13.1 3.1 1.2 8.7 0.6 2.2 2 0 0 2 2 2 0 IncA protein SdpI PF13630.1 GAM26942.1 - 0.063 12.9 3.0 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family CUB_2 PF02408.15 GAM26942.1 - 0.1 12.1 0.2 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 CUB-like domain DUF202 PF02656.10 GAM26942.1 - 0.14 12.3 0.2 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3185 PF11381.3 GAM26942.1 - 1.5 8.6 5.4 46 3.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) PsbX PF06596.6 GAM26942.1 - 6.5 6.5 9.7 0.063 12.9 1.3 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) PGPGW PF09656.5 GAM26942.1 - 9 5.6 10.0 19 4.6 0.2 2.3 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Pkinase PF00069.20 GAM26943.1 - 5.1e-70 235.5 0.0 9.8e-70 234.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26943.1 - 1.7e-48 164.9 0.0 3.3e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CSTF2_hinge PF14327.1 GAM26943.1 - 0.00026 21.0 0.6 0.00026 21.0 0.4 3.1 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 Kinase-like PF14531.1 GAM26943.1 - 0.0015 17.5 0.0 0.0072 15.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Adaptin_N PF01602.15 GAM26943.1 - 0.018 13.3 10.5 0.067 11.4 3.4 2.6 2 1 0 2 2 2 0 Adaptin N terminal region V-ATPase_H_C PF11698.3 GAM26943.1 - 0.038 13.9 2.0 0.13 12.1 1.4 2.0 1 0 0 1 1 1 0 V-ATPase subunit H Kdo PF06293.9 GAM26943.1 - 0.043 12.8 0.0 0.093 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ParcG PF10274.4 GAM26943.1 - 0.1 12.5 3.4 0.085 12.7 0.5 2.2 2 0 0 2 2 2 0 Parkin co-regulated protein DUF3385 PF11865.3 GAM26943.1 - 1.1 9.1 8.3 0.49 10.2 1.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) Oxysterol_BP PF01237.13 GAM26944.1 - 1.9e-47 161.5 9.1 3.9e-47 160.4 6.3 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1084 PF06454.6 GAM26945.1 - 4.1e-16 58.8 13.9 4.9e-16 58.5 9.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) VIT1 PF01988.14 GAM26945.1 - 0.0083 15.6 0.3 0.0083 15.6 0.2 3.0 3 0 0 3 3 3 1 VIT family UPF0233 PF06781.7 GAM26945.1 - 0.021 14.4 1.9 0.021 14.4 1.3 3.1 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) DUF373 PF04123.8 GAM26945.1 - 0.42 9.5 13.5 0.097 11.6 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Pox_A14 PF05767.7 GAM26945.1 - 2.2 8.2 9.5 0.36 10.8 0.2 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 EamA PF00892.15 GAM26945.1 - 8 6.5 23.9 1 9.3 3.5 3.5 3 2 0 3 3 3 0 EamA-like transporter family WD40 PF00400.27 GAM26946.1 - 2e-22 78.2 7.6 2.2e-06 27.3 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat F-box-like PF12937.2 GAM26946.1 - 1.2e-10 40.9 0.2 3.1e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM26946.1 - 6.4e-08 32.0 0.3 1.4e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain Sporozoite_P67 PF05642.6 GAM26946.1 - 4.7 4.9 8.4 0.87 7.3 2.7 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Dicty_REP PF05086.7 GAM26946.1 - 8.4 4.0 5.7 15 3.1 3.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MecA PF05389.7 GAM26947.1 - 0.00052 19.6 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Glyco_transf_49 PF13896.1 GAM26948.1 - 1.6e-46 158.8 1.3 2.2e-40 138.6 0.2 2.4 2 1 1 3 3 3 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM26948.1 - 0.00011 21.3 0.2 0.00037 19.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM26948.1 - 0.0008 19.1 2.0 0.0022 17.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Secretin_N_2 PF07655.8 GAM26948.1 - 0.22 11.9 18.3 0.41 11.0 12.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1084 PF06454.6 GAM26950.1 - 3.5e-11 42.6 17.5 4.7e-11 42.2 12.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) L6_membrane PF05805.7 GAM26950.1 - 0.038 13.5 7.4 0.23 10.9 0.0 3.2 1 1 2 3 3 3 0 L6 membrane protein DUF2668 PF10873.3 GAM26950.1 - 8.7 6.4 6.3 0.81 9.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) AAA_17 PF13207.1 GAM26951.1 - 4.1e-10 40.5 0.0 8.3e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM26951.1 - 3e-07 30.7 0.0 6.7e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 GAM26951.1 - 4.1e-07 29.7 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 GAM26951.1 - 2.5e-06 27.3 0.0 5.2e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM26951.1 - 2.8e-05 23.3 0.1 0.00029 20.0 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin ArgK PF03308.11 GAM26951.1 - 0.00014 20.7 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 GAM26951.1 - 0.00061 19.8 0.2 0.0015 18.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAM26951.1 - 0.0011 17.9 0.0 0.012 14.4 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 GAM26951.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 GAM26951.1 - 0.0034 17.3 0.0 0.0077 16.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.10 GAM26951.1 - 0.0036 16.0 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 GAM26951.1 - 0.0047 17.1 0.0 0.0079 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM26951.1 - 0.0058 15.7 0.1 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM26951.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 GAM26951.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 GAM26951.1 - 0.012 15.3 0.1 0.03 14.0 0.0 1.8 2 1 0 2 2 2 0 NTPase SKI PF01202.17 GAM26951.1 - 0.014 15.2 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_5 PF07728.9 GAM26951.1 - 0.02 14.6 0.0 0.082 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PyocinActivator PF11112.3 GAM26951.1 - 0.023 14.5 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 0 Pyocin activator protein PrtN AAA_28 PF13521.1 GAM26951.1 - 0.029 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 GAM26951.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.1 GAM26951.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 GAM26951.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM26951.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 GAM26951.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase F-box PF00646.28 GAM26952.1 - 0.0013 18.3 0.5 0.0013 18.3 0.3 2.6 3 0 0 3 3 3 1 F-box domain JCAD PF15351.1 GAM26952.1 - 0.12 9.9 0.0 0.17 9.5 0.0 1.1 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Adeno_E3_CR2 PF02439.10 GAM26955.1 - 0.022 14.3 0.7 0.049 13.1 0.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EGF_2 PF07974.8 GAM26955.1 - 0.022 14.9 14.1 0.051 13.7 9.8 1.7 1 0 0 1 1 1 0 EGF-like domain DAP10 PF07213.6 GAM26955.1 - 0.067 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 DAP10 membrane protein Melibiase PF02065.13 GAM26956.1 - 7.6e-22 77.5 1.0 4.8e-18 65.0 0.0 2.5 2 1 1 3 3 3 2 Melibiase Glyco_hydro_97 PF10566.4 GAM26956.1 - 0.0023 17.0 0.1 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Raffinose_syn PF05691.7 GAM26956.1 - 0.034 11.6 0.1 0.046 11.2 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 zf-DHHC PF01529.15 GAM26957.1 - 5.8e-44 149.5 6.3 5.8e-44 149.5 4.3 2.6 1 1 1 3 3 3 1 DHHC palmitoyltransferase DUF2207 PF09972.4 GAM26957.1 - 0.00017 20.3 0.9 0.012 14.2 0.1 2.1 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) Spt4 PF06093.8 GAM26957.1 - 0.64 9.9 6.0 1.4 8.8 4.2 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Secretin_N_2 PF07655.8 GAM26957.1 - 3 8.2 12.1 6.5 7.2 8.4 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF975 PF06161.6 GAM26957.1 - 5.2 6.7 13.5 0.46 10.1 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF975) DUF4092 PF13322.1 GAM26958.1 - 0.027 14.2 0.4 0.044 13.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4092) Kelch_6 PF13964.1 GAM26958.1 - 0.093 12.9 0.3 34 4.8 0.0 3.3 4 0 0 4 4 4 0 Kelch motif SseB PF07179.7 GAM26960.1 - 0.073 12.8 0.1 2 8.2 0.2 2.5 2 0 0 2 2 2 0 SseB protein N-terminal domain Band_3_cyto PF07565.8 GAM26960.1 - 0.1 12.0 5.7 0.17 11.3 4.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Dicty_REP PF05086.7 GAM26960.1 - 2.2 5.9 9.4 2.8 5.6 6.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA_25 PF13481.1 GAM26961.1 - 0.036 13.4 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 GAM26961.1 - 0.25 11.2 1.4 4.6 7.1 0.3 2.9 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.2 GAM26962.1 - 0.00036 20.8 0.2 0.53 10.6 0.1 3.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM26962.1 - 0.0057 16.8 5.9 2.9 8.2 0.0 5.6 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM26962.1 - 0.0064 16.6 0.6 0.61 10.5 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat TFIIS_M PF07500.9 GAM26963.1 - 3.2e-16 59.4 0.7 6.4e-16 58.4 0.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 GAM26963.1 - 1.3e-09 37.3 1.2 3.8e-09 35.9 0.8 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MRP-S25 PF13741.1 GAM26963.1 - 0.15 11.5 1.0 0.21 11.0 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 ORC6 PF05460.8 GAM26963.1 - 1.4 7.9 14.4 1.8 7.5 10.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.5 GAM26963.1 - 1.5 7.1 9.7 1.6 7.0 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SR-25 PF10500.4 GAM26963.1 - 1.6 8.1 13.0 2.2 7.7 9.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cyto_heme_lyase PF01265.12 GAM26963.1 - 2.3 7.7 9.8 3.1 7.3 6.8 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase TPR_1 PF00515.23 GAM26964.1 - 3.6e-44 146.6 3.3 1.8e-07 30.4 0.0 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 GAM26964.1 - 3.7e-42 141.8 6.6 5.7e-11 41.8 0.3 5.4 2 1 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 GAM26964.1 - 3.3e-36 120.2 4.4 8.8e-07 28.3 0.0 8.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 GAM26964.1 - 2e-24 83.4 0.9 1.7e-05 24.2 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM26964.1 - 1.3e-21 76.2 11.6 1e-06 28.5 0.1 6.1 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 GAM26964.1 - 2e-21 74.3 5.0 0.00039 20.4 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM26964.1 - 2.3e-20 72.7 0.0 0.00047 20.7 0.0 5.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM26964.1 - 5e-16 58.3 0.5 0.00065 19.4 0.0 6.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM26964.1 - 8.9e-11 41.4 0.5 0.54 11.0 0.0 6.6 3 2 4 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM26964.1 - 3.1e-10 40.0 8.0 0.0028 17.7 0.0 4.7 2 1 2 5 5 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM26964.1 - 1.3e-09 37.8 1.6 0.046 14.1 0.1 6.3 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM26964.1 - 5.9e-08 31.9 3.4 0.18 11.6 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM26964.1 - 6.7e-08 32.7 1.6 0.12 12.7 0.0 5.6 3 1 3 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM26964.1 - 1.5e-06 27.9 1.8 1.2 9.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 GAM26964.1 - 0.00027 19.8 3.2 0.79 8.4 0.0 4.4 2 2 3 5 5 5 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 GAM26964.1 - 0.013 15.6 0.1 2.3 8.3 0.0 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF479 PF04336.7 GAM26964.1 - 0.013 15.6 4.4 0.27 11.3 0.6 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF479 Phage_int_SAM_1 PF02899.12 GAM26964.1 - 0.039 14.0 0.8 14 5.8 0.0 3.1 3 0 0 3 3 2 0 Phage integrase, N-terminal SAM-like domain Fis1_TPR_C PF14853.1 GAM26964.1 - 0.063 13.1 4.2 6.2 6.7 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Ank_2 PF12796.2 GAM26965.1 - 0.0078 16.5 8.6 1.7 9.0 0.1 5.3 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) OB_NTP_bind PF07717.11 GAM26966.1 - 4.4e-32 110.2 0.0 1.1e-31 109.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM26966.1 - 8.7e-30 102.7 0.1 8.7e-30 102.7 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) S1 PF00575.18 GAM26966.1 - 2.5e-12 46.7 0.7 7.4e-12 45.1 0.5 1.9 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 GAM26966.1 - 1.7e-11 43.7 0.0 8.1e-11 41.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM26966.1 - 2.6e-07 30.2 0.0 6.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM26966.1 - 9.3e-06 25.8 0.0 2.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 GAM26966.1 - 0.00082 18.3 0.0 0.0018 17.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 GAM26966.1 - 0.0029 17.3 0.5 0.0073 16.0 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 GAM26966.1 - 0.012 15.4 1.7 2.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 GAM26966.1 - 0.022 14.5 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 GAM26966.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 GAM26966.1 - 0.064 12.4 0.2 0.37 9.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DAGK_cat PF00781.19 GAM26967.1 - 2.9e-23 81.7 0.1 6.9e-23 80.4 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF3456 PF11938.3 GAM26967.1 - 0.0016 18.4 0.1 0.0042 17.0 0.1 1.7 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP NAD_kinase PF01513.16 GAM26967.1 - 0.0063 15.3 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF4279 PF14106.1 GAM26967.1 - 0.28 11.0 1.7 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) Yae1_N PF09811.4 GAM26968.1 - 2.3e-09 36.6 3.1 2.3e-09 36.6 2.2 1.6 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Phage_tail_U PF06141.6 GAM26968.1 - 0.13 12.3 0.2 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Phage minor tail protein U CGI-121 PF08617.5 GAM26968.1 - 0.14 11.8 0.1 0.27 10.8 0.0 1.4 2 0 0 2 2 2 0 Kinase binding protein CGI-121 Amidinotransf PF02274.12 GAM26969.1 - 1.8e-69 233.9 0.4 4.5e-44 150.6 0.0 3.1 3 0 0 3 3 3 3 Amidinotransferase FNIP PF05725.7 GAM26970.1 - 1.2e-09 38.0 11.6 1.9e-05 24.5 0.6 3.7 2 1 1 3 3 3 3 FNIP Repeat LRR_1 PF00560.28 GAM26970.1 - 0.14 12.2 1.3 28 5.2 0.0 3.9 4 2 0 4 4 4 0 Leucine Rich Repeat Kelch_6 PF13964.1 GAM26971.1 - 4.1e-12 45.7 5.0 0.00037 20.5 0.0 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM26971.1 - 2.9e-09 36.5 7.2 0.0012 18.5 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM26971.1 - 8.4e-08 32.1 4.8 0.36 11.0 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM26971.1 - 3.6e-05 23.3 5.5 1.3 8.9 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 GAM26971.1 - 4.7e-05 22.8 10.4 0.02 14.4 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 GAM26971.1 - 0.45 10.5 10.0 5.4 7.0 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Peptidase_C1 PF00112.18 GAM26972.1 - 9.5e-74 247.9 10.8 5.5e-61 206.2 2.6 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM26972.1 - 6.4e-15 55.1 1.7 1.2e-14 54.3 1.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM26972.1 - 0.00037 19.1 1.4 0.042 12.3 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family eIF_4EBP PF05456.6 GAM26973.1 - 1.2e-24 86.2 1.7 1.7e-24 85.7 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) GTP_EFTU PF00009.22 GAM26974.1 - 5.7e-27 94.3 0.0 1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM26974.1 - 1.7e-14 53.7 1.0 1.4e-12 47.5 0.1 2.6 1 1 1 2 2 2 2 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM26974.1 - 3.9e-08 33.2 0.6 3.9e-08 33.2 0.4 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM26974.1 - 0.0037 17.2 0.1 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM26974.1 - 0.0052 17.2 0.1 0.081 13.4 0.1 2.7 1 1 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 GAM26974.1 - 0.0071 15.8 0.1 22 4.5 0.0 3.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ImcF-related_N PF14331.1 GAM26974.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 ImcF-related N-terminal domain p450 PF00067.17 GAM26975.1 - 1.5e-44 152.2 0.1 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Hex_IIIa PF02455.11 GAM26975.1 - 0.72 8.4 6.1 6.2 5.3 0.0 2.2 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) MFS_1 PF07690.11 GAM26976.1 - 4.6e-38 130.8 19.7 6.9e-22 77.6 4.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM26976.1 - 6e-14 51.4 18.6 1.1e-13 50.5 12.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 GAM26976.1 - 1.7e-07 30.0 10.0 0.00016 20.2 2.5 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein OppC_N PF12911.2 GAM26976.1 - 3.5 7.0 5.8 12 5.3 0.1 3.7 3 1 1 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Peptidase_M15 PF01427.12 GAM26978.1 - 0.0087 15.6 0.2 0.0087 15.6 0.1 1.7 2 0 0 2 2 2 1 D-ala-D-ala dipeptidase zf-CHC2 PF01807.15 GAM26979.1 - 1.8 8.1 6.5 3.3 7.3 3.8 1.9 1 1 1 2 2 2 0 CHC2 zinc finger Pinin_SDK_memA PF04696.8 GAM26980.1 - 7.6e-21 74.0 11.3 7.6e-21 74.0 7.9 3.1 3 2 2 5 5 5 1 pinin/SDK/memA/ protein conserved region FNIP PF05725.7 GAM26981.1 - 1.8e-20 72.6 24.9 2.7e-05 24.0 0.3 8.4 5 2 4 9 9 9 7 FNIP Repeat FNIP PF05725.7 GAM26982.1 - 2.4e-20 72.2 30.2 7.8e-07 28.9 3.0 7.9 6 2 2 8 8 8 6 FNIP Repeat AAA_14 PF13173.1 GAM26982.1 - 0.0027 17.6 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RVT_1 PF00078.22 GAM26984.1 - 5.6e-06 25.8 0.2 9.3e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 GAM26985.1 - 0.00022 20.6 0.0 0.00081 18.7 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf15 PF10705.4 GAM26987.1 - 1.2 9.1 6.7 19 5.3 0.1 3.2 3 0 0 3 3 3 0 Chloroplast protein precursor Ycf15 putative RYDR_ITPR PF01365.16 GAM26988.1 - 2.7e-29 101.9 8.8 4.8e-17 61.8 0.3 4.8 3 2 1 4 4 4 2 RIH domain RIH_assoc PF08454.6 GAM26988.1 - 3e-17 62.2 2.5 3e-17 62.2 1.8 3.9 4 0 0 4 4 4 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.6 GAM26988.1 - 2.3e-16 59.4 0.1 5.9e-16 58.1 0.1 1.7 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RCC1 PF00415.13 GAM26989.1 - 5.7e-70 231.3 4.1 1.8e-14 53.6 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM26989.1 - 3e-37 125.4 22.6 1.9e-10 40.0 1.3 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.1 GAM26989.1 - 0.02 14.6 2.2 9.8 5.9 0.0 3.4 2 1 1 3 3 3 0 SUKH-3 immunity protein Pkinase PF00069.20 GAM26990.1 - 2.6e-57 193.9 0.0 7e-32 110.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM26990.1 - 1.3e-34 119.4 0.0 1.9e-16 59.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase DUF3543 PF12063.3 GAM26990.1 - 3.8e-13 49.2 0.0 4.5e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) MIT PF04212.13 GAM26990.1 - 0.013 15.3 0.1 0.061 13.2 0.0 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SpoU_methylase PF00588.14 GAM26991.1 - 3.7e-15 56.0 0.0 5.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 GAM26991.1 - 0.0099 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF3014 PF11219.3 GAM26992.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3014) Chorein_N PF12624.2 GAM26992.1 - 0.0083 15.6 0.1 0.034 13.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Pkinase_Tyr PF07714.12 GAM26993.1 - 1.8e-45 155.0 0.0 2.6e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 GAM26993.1 - 2e-45 154.9 0.0 7.8e-45 153.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.15 GAM26993.1 - 1.1e-34 119.8 5.9 3e-34 118.4 4.1 1.8 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM26993.1 - 0.0031 17.7 1.1 0.034 14.3 0.3 2.9 2 1 0 2 2 2 1 PH domain UPF0066 PF01980.11 GAM26993.1 - 0.0075 16.2 0.1 0.06 13.2 0.1 2.2 1 1 0 1 1 1 1 Uncharacterised protein family UPF0066 IQ PF00612.22 GAM26993.1 - 0.063 12.9 0.2 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif ALS_ss_C PF10369.4 GAM26993.1 - 0.15 11.8 0.1 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Small subunit of acetolactate synthase PX PF00787.19 GAM26995.1 - 3.1e-20 72.0 1.3 3.1e-20 72.0 0.9 1.7 2 0 0 2 2 2 1 PX domain NYD-SP28_assoc PF14775.1 GAM26995.1 - 0.027 14.1 8.3 0.47 10.1 0.9 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain HNF-1_N PF04814.8 GAM26995.1 - 0.037 14.1 1.2 0.095 12.7 0.1 2.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mto2_bdg PF12808.2 GAM26995.1 - 0.076 13.1 7.6 0.13 12.3 0.5 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region AAA_14 PF13173.1 GAM26995.1 - 0.081 12.8 0.1 0.73 9.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF2874 PF11396.3 GAM26995.1 - 0.24 11.4 1.2 0.45 10.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Herpes_BLRF2 PF05812.7 GAM26995.1 - 4.3 7.1 7.3 36 4.1 4.9 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein NUDIX PF00293.23 GAM26997.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 NUDIX domain PEMT PF04191.8 GAM26998.1 - 1e-28 99.5 1.5 1e-28 99.5 1.1 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 GAM26998.1 - 0.00045 20.0 1.1 0.00067 19.4 0.6 1.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 GAM26998.1 - 0.018 15.2 1.2 0.038 14.1 0.1 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-CCHC PF00098.18 GAM26999.1 - 1.6e-21 75.0 44.8 6.8e-06 25.7 1.5 5.3 3 1 2 5 5 5 5 Zinc knuckle Sporozoite_P67 PF05642.6 GAM26999.1 - 0.00083 17.3 14.0 0.0011 16.9 9.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen zf-CCHC_4 PF14392.1 GAM26999.1 - 0.0019 17.8 37.5 0.08 12.6 0.3 5.4 2 1 3 5 5 5 5 Zinc knuckle SSrecog PF03531.9 GAM26999.1 - 0.15 11.4 1.3 0.25 10.6 0.9 1.3 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) zf-CCHC_3 PF13917.1 GAM26999.1 - 0.71 9.6 33.0 0.084 12.6 0.5 4.7 1 1 3 4 4 4 0 Zinc knuckle CytochromB561_N PF09786.4 GAM26999.1 - 1.5 7.1 8.0 2.9 6.2 5.5 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ndc1_Nup PF09531.5 GAM26999.1 - 2.4 6.4 3.7 2.7 6.3 2.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CTP_transf_1 PF01148.15 GAM27000.1 - 1.5e-67 227.9 31.7 1.8e-67 227.6 22.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF373 PF04123.8 GAM27000.1 - 1.1 8.1 16.2 0.31 10.0 8.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Ashwin PF15323.1 GAM27000.1 - 1.3 8.9 5.7 1.8 8.5 3.9 1.1 1 0 0 1 1 1 0 Developmental protein Pkinase PF00069.20 GAM27001.1 - 4.4e-46 157.1 0.3 1.9e-26 92.7 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27001.1 - 5.6e-14 51.8 0.7 1.2e-10 40.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase PP2C_2 PF13672.1 GAM27002.1 - 9.7e-06 25.1 0.0 2.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM27002.1 - 0.0076 15.9 0.0 0.024 14.3 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Clat_adaptor_s PF01217.15 GAM27003.1 - 1.4e-50 170.7 6.1 1.7e-50 170.4 4.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FNIP PF05725.7 GAM27004.1 - 1.8e-18 66.1 12.6 1.2e-13 50.7 0.6 3.2 2 1 1 3 3 3 3 FNIP Repeat DUF3818 PF12825.2 GAM27005.1 - 2.9e-17 62.3 3.7 2.4e-11 42.9 0.4 3.8 3 1 0 4 4 4 2 Domain of unknown function in PX-proteins (DUF3818) p450 PF00067.17 GAM27006.1 - 0.0059 15.1 0.2 0.01 14.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 WBS_methylT PF12589.3 GAM27006.1 - 0.15 12.5 8.7 0.29 11.6 6.1 1.5 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome YjcZ PF13990.1 GAM27006.1 - 0.32 10.0 4.1 0.39 9.7 2.9 1.1 1 0 0 1 1 1 0 YjcZ-like protein RNase_H2-Ydr279 PF09468.5 GAM27006.1 - 0.34 10.0 7.1 0.42 9.7 4.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 GAM27006.1 - 0.34 10.8 10.1 0.37 10.7 7.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 GAM27006.1 - 1.4 8.9 10.9 1.9 8.5 7.5 1.2 1 0 0 1 1 1 0 YqfQ-like protein Cluap1 PF10234.4 GAM27006.1 - 1.6 7.8 10.0 1.9 7.6 6.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Presenilin PF01080.12 GAM27006.1 - 2 7.1 4.0 2.1 7.0 2.8 1.0 1 0 0 1 1 1 0 Presenilin Laps PF10169.4 GAM27006.1 - 5.2 7.3 23.4 27 5.0 16.2 1.9 1 1 0 1 1 1 0 Learning-associated protein Tom37_C PF11801.3 GAM27006.1 - 7.9 6.3 7.7 9.7 6.0 5.3 1.4 1 1 0 1 1 1 0 Tom37 C-terminal domain Ribonucleas_3_3 PF14622.1 GAM27007.1 - 1.3e-06 28.3 1.2 1.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like DUF4557 PF15101.1 GAM27007.1 - 0.0022 17.8 6.4 0.0025 17.6 3.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) SprA-related PF12118.3 GAM27007.1 - 0.065 12.5 14.2 0.1 11.9 9.8 1.2 1 0 0 1 1 1 0 SprA-related family NMT_C PF02799.10 GAM27007.1 - 0.31 10.3 4.5 0.55 9.5 0.0 3.0 2 1 1 3 3 3 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain BAF1_ABF1 PF04684.8 GAM27007.1 - 7.1 5.3 25.9 11 4.7 17.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ank_2 PF12796.2 GAM27008.1 - 1.1e-51 173.1 40.5 5.3e-08 33.0 0.0 8.5 2 2 9 12 12 12 11 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM27008.1 - 4.8e-34 115.6 21.0 0.00027 21.0 0.2 15.7 4 2 13 18 18 18 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM27008.1 - 5.3e-34 115.9 18.4 2e-05 24.9 0.3 11.2 7 2 3 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27008.1 - 3.7e-28 94.7 24.8 0.015 15.4 0.1 16.0 11 3 7 18 18 18 8 Ankyrin repeat Ank PF00023.25 GAM27008.1 - 1.3e-20 72.0 24.6 0.01 15.6 0.3 15.1 17 0 0 17 17 17 7 Ankyrin repeat DUF249 PF03158.8 GAM27008.1 - 7.1e-09 35.4 15.1 0.00041 19.9 0.5 6.0 3 3 3 6 6 6 3 Multigene family 530 protein PET122 PF05476.6 GAM27008.1 - 0.024 13.9 0.9 7.5 5.7 0.0 3.9 3 2 0 4 4 4 0 PET122 RTC PF01137.16 GAM27009.1 - 1.2e-70 236.8 0.0 1.3e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 GAM27009.1 - 2.9e-36 123.6 0.0 4.5e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Cyt-b5 PF00173.23 GAM27010.1 - 7.9e-08 31.9 0.1 9.8e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FNIP PF05725.7 GAM27011.1 - 2.8e-62 206.4 27.4 1.6e-12 47.1 0.0 8.3 4 2 5 9 9 9 9 FNIP Repeat DUF3605 PF12239.3 GAM27012.1 - 3.4e-18 65.9 3.5 2.2e-12 47.1 0.3 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3605) DUF2359 PF10151.4 GAM27013.1 - 8.2e-08 31.1 2.0 8.2e-08 31.1 1.4 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2359) BP28CT PF08146.7 GAM27014.1 - 1.1e-28 99.8 8.3 1.5e-27 96.1 3.7 4.2 2 1 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 GAM27014.1 - 7.2e-16 58.2 0.4 7.2e-16 58.2 0.3 7.9 7 0 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 GAM27014.1 - 1.7e-06 28.1 9.7 1.1 9.6 0.0 7.9 8 0 0 8 8 8 2 HEAT repeats HEAT PF02985.17 GAM27014.1 - 1.8e-05 24.4 8.6 0.011 15.6 0.1 7.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 GAM27014.1 - 0.0003 21.1 11.3 0.21 12.1 0.1 7.9 8 1 0 8 8 8 2 HEAT-like repeat Arm PF00514.18 GAM27014.1 - 0.036 13.8 5.5 18 5.3 0.1 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DNA_primase_S PF01896.14 GAM27015.1 - 5.3e-38 130.0 0.4 1.1e-37 129.0 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit FNIP PF05725.7 GAM27016.1 - 3.3e-45 151.7 11.4 3.2e-12 46.2 0.2 6.4 3 1 1 6 6 6 5 FNIP Repeat LRR_7 PF13504.1 GAM27016.1 - 2.9 8.4 4.8 50 4.7 0.1 4.7 5 0 0 5 5 5 0 Leucine rich repeat PALP PF00291.20 GAM27017.1 - 2.2e-69 234.0 1.2 2.5e-69 233.8 0.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FNIP PF05725.7 GAM27018.1 - 2.2e-09 37.1 3.5 0.029 14.3 0.0 6.8 5 3 1 6 6 6 4 FNIP Repeat p450 PF00067.17 GAM27019.1 - 1.1e-105 353.9 3.7 1.2e-105 353.7 2.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 VWA_3 PF13768.1 GAM27020.1 - 1.5e-28 99.3 0.0 2.9e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 GAM27020.1 - 1.6e-22 79.3 2.6 4.2e-22 78.0 1.3 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 GAM27020.1 - 1.5e-11 44.3 0.0 6.8e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 GAM27020.1 - 6.9e-10 39.2 0.0 1.9e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAM27020.1 - 1.4e-07 30.8 0.1 3.1e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 GAM27020.1 - 0.00011 22.1 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Prenyltrans_2 PF13249.1 GAM27020.1 - 0.0057 17.0 0.1 0.043 14.2 0.0 2.3 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 GAM27020.1 - 0.07 13.1 0.1 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 Prenyltransferase-like FAD_binding_3 PF01494.14 GAM27021.1 - 4.9e-16 58.7 4.4 1e-12 47.7 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM27021.1 - 0.00015 21.7 0.1 0.00039 20.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 GAM27021.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM27021.1 - 0.0035 17.7 1.0 0.62 10.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase N2227 PF07942.7 GAM27021.1 - 0.061 12.2 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein VKG_Carbox PF05090.9 GAM27022.1 - 9e-08 31.3 14.7 9e-08 31.3 10.2 2.2 2 0 0 2 2 2 2 Vitamin K-dependent gamma-carboxylase TPR_6 PF13174.1 GAM27022.1 - 0.069 13.6 0.0 0.32 11.5 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat E1_DerP2_DerF2 PF02221.10 GAM27024.1 - 1.3e-21 77.2 0.1 1.4e-21 77.1 0.1 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 GAM27024.1 - 3.5e-05 23.8 0.3 5e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 ML-like domain DUF4625 PF15418.1 GAM27024.1 - 0.04 14.0 0.0 0.087 12.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) FlgD_ig PF13860.1 GAM27024.1 - 0.043 13.5 0.4 0.8 9.4 0.1 2.4 2 1 1 3 3 3 0 FlgD Ig-like domain Big_1 PF02369.11 GAM27024.1 - 0.076 12.9 0.3 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) RasGEF PF00617.14 GAM27027.1 - 3e-53 180.3 3.6 6.8e-53 179.1 2.5 1.6 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.24 GAM27027.1 - 2.6e-22 78.4 0.0 1.5e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.15 GAM27027.1 - 8.6e-14 51.5 2.0 1.4e-13 50.8 0.5 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif GRAM PF02893.15 GAM27027.1 - 4.2e-11 42.2 0.1 1.1e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 GRAM domain CLU PF13236.1 GAM27028.1 - 3.8e-57 193.2 0.0 1.1e-56 191.7 0.0 1.8 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 GAM27028.1 - 1.2e-09 38.2 0.0 3.2e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_4 PF12799.2 GAM27028.1 - 0.00043 19.8 3.4 5.8 6.6 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) IER PF05760.7 GAM27028.1 - 2.3 8.0 7.6 3.9 7.3 5.2 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) RhoGEF PF00621.15 GAM27029.1 - 1.1e-37 129.6 0.8 1.7e-37 129.0 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain DUF4214 PF13946.1 GAM27030.1 - 0.00013 21.6 0.0 0.0006 19.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4214) vMSA PF00695.14 GAM27030.1 - 0.0019 17.5 3.5 0.0024 17.1 2.4 1.1 1 0 0 1 1 1 1 Major surface antigen from hepadnavirus PAT1 PF09770.4 GAM27030.1 - 0.0066 14.7 9.8 0.0078 14.5 6.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 ORC6 PF05460.8 GAM27030.1 - 0.014 14.5 1.2 0.018 14.1 0.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Lipoxygenase PF00305.14 GAM27031.1 - 1.6e-06 26.4 8.0 0.0002 19.4 5.3 2.8 2 1 0 2 2 2 1 Lipoxygenase TIG PF01833.19 GAM27032.1 - 7.6e-09 35.4 29.0 6.2e-05 22.9 0.3 5.1 5 0 0 5 5 5 3 IPT/TIG domain DUF1191 PF06697.7 GAM27032.1 - 0.0067 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EGF_2 PF07974.8 GAM27032.1 - 0.025 14.7 14.1 0.061 13.5 9.8 1.7 1 0 0 1 1 1 0 EGF-like domain Thioredoxin_8 PF13905.1 GAM27033.1 - 0.0074 16.3 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 GAM27033.1 - 0.03 14.5 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.15 GAM27033.1 - 0.053 13.1 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin RhoGAP PF00620.22 GAM27034.1 - 1.1e-25 89.9 0.3 4.3e-25 88.0 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 GAM27034.1 - 8.2e-10 38.7 0.1 8.2e-10 38.7 0.1 2.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SMN PF06003.7 GAM27034.1 - 0.075 12.1 3.3 0.15 11.1 2.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF3270 PF11674.3 GAM27035.1 - 0.0062 16.5 1.2 0.018 15.0 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3270) SKG6 PF08693.5 GAM27036.1 - 0.0037 16.5 2.1 0.0078 15.5 1.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.1 GAM27036.1 - 0.16 10.4 0.4 0.32 9.4 0.1 1.6 2 0 0 2 2 2 0 Amnionless Guanylate_cyc PF00211.15 GAM27037.1 - 6.6e-49 165.7 0.4 1.4e-48 164.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain MHYT PF03707.11 GAM27037.1 - 4e-20 71.6 37.8 1.1e-11 44.6 3.7 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat HNOBA PF07701.9 GAM27037.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Heme NO binding associated DUF1352 PF07086.7 GAM27037.1 - 0.15 11.6 8.5 0.28 10.7 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) LSM PF01423.17 GAM27038.1 - 5.6e-21 73.8 0.6 6.3e-21 73.6 0.4 1.0 1 0 0 1 1 1 1 LSM domain FACT-Spt16_Nlob PF14826.1 GAM27039.1 - 4e-48 163.0 1.3 8e-48 162.0 0.2 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.6 GAM27039.1 - 5.3e-45 152.9 0.5 5.3e-45 152.9 0.3 4.1 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 GAM27039.1 - 5.7e-27 94.6 0.0 9.3e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 GAM27039.1 - 2e-19 69.3 3.6 2.3e-19 69.1 0.1 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like HECT PF00632.20 GAM27040.1 - 9.4e-92 307.5 0.2 1.7e-91 306.6 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 GAM27040.1 - 2e-05 24.2 5.0 2.9 7.8 0.0 5.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAM27040.1 - 3.4e-05 23.5 0.6 0.6 10.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 GAM27040.1 - 4.4e-05 23.6 0.1 0.53 10.6 0.1 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 GAM27040.1 - 0.0004 20.7 1.7 0.0029 18.0 0.0 3.2 3 0 0 3 3 3 1 HEAT-like repeat G-patch PF01585.18 GAM27041.1 - 1.9e-09 37.1 0.2 5.8e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM27041.1 - 0.0066 16.2 0.0 0.0066 16.2 0.0 2.6 3 0 0 3 3 3 1 DExH-box splicing factor binding site Elf1 PF05129.8 GAM27041.1 - 0.019 14.6 0.4 0.019 14.6 0.3 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like NAD_binding_5 PF07994.7 GAM27041.1 - 0.092 12.2 2.7 0.14 11.6 1.9 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF2547 PF10818.3 GAM27042.1 - 0.01 16.4 0.5 0.027 15.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) DUF4610 PF15384.1 GAM27042.1 - 0.048 13.1 0.7 0.08 12.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) Peptidase_S64 PF08192.6 GAM27042.1 - 1.1 7.5 6.2 1.3 7.2 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Oxidored_q6 PF01058.17 GAM27043.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.6 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF2681 PF10883.3 GAM27043.1 - 0.025 14.7 0.1 0.025 14.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF533 PF04391.7 GAM27043.1 - 0.051 12.9 0.1 0.14 11.5 0.0 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF533) DUF4366 PF14283.1 GAM27043.1 - 0.088 12.2 0.2 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tnp_P_element PF12017.3 GAM27043.1 - 0.16 11.1 6.8 2.5 7.2 0.1 2.1 2 0 0 2 2 2 0 Transposase protein DUF2203 PF09969.4 GAM27043.1 - 0.29 11.3 4.9 0.88 9.8 1.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) WXG100 PF06013.7 GAM27043.1 - 0.4 10.7 8.7 0.76 9.8 1.3 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Fib_alpha PF08702.5 GAM27043.1 - 0.6 10.2 12.0 0.076 13.1 0.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MSC PF09402.5 GAM27043.1 - 0.72 8.5 4.5 0.46 9.1 0.0 2.2 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain SHR3_chaperone PF08229.6 GAM27043.1 - 0.86 8.5 3.6 0.3 10.0 0.1 1.9 1 1 1 2 2 2 0 ER membrane protein SH3 FKBP_N PF01346.13 GAM27043.1 - 2 8.4 6.5 0.4 10.7 1.3 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TBPIP PF07106.8 GAM27043.1 - 6.1 6.3 12.5 2.5 7.6 4.5 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Aminotran_1_2 PF00155.16 GAM27044.1 - 2.8e-58 197.5 0.0 3.3e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 GAM27044.1 - 8.4e-06 24.3 0.0 1.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 GAM27044.1 - 0.0013 17.6 0.0 0.0033 16.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 GAM27044.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 GAM27044.1 - 0.013 13.8 0.0 0.017 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Aminotran_MocR PF12897.2 GAM27044.1 - 0.049 12.1 0.0 0.16 10.5 0.0 1.7 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase BTB_2 PF02214.17 GAM27045.1 - 5.5e-18 64.9 0.0 9.5e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 GAM27045.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain LMBR1 PF04791.11 GAM27047.1 - 1.5e-15 56.8 8.8 1.5e-15 56.8 6.1 2.4 2 1 1 3 3 3 2 LMBR1-like membrane protein TarH PF02203.10 GAM27047.1 - 0.0074 16.1 0.4 0.0074 16.1 0.3 2.7 3 1 0 3 3 3 1 Tar ligand binding domain homologue Asp-Al_Ex PF06826.7 GAM27047.1 - 0.018 14.5 0.4 0.018 14.5 0.3 3.9 4 1 0 4 4 4 0 Predicted Permease Membrane Region Anophelin PF10731.4 GAM27047.1 - 1.4 9.0 5.0 0.4 10.8 0.1 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Alpha-mann_mid PF09261.6 GAM27049.1 - 1.1e-17 63.9 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38C PF07748.8 GAM27049.1 - 6.5e-08 31.7 0.0 8.3e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain UDPGP PF01704.13 GAM27050.1 - 2.2e-158 527.1 3.8 2.7e-158 526.9 2.6 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Gaa1 PF04114.9 GAM27051.1 - 3.5e-68 230.5 12.9 1.3e-66 225.3 8.9 2.2 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component APH PF01636.18 GAM27052.1 - 5.7e-20 72.0 0.0 7.3e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM27052.1 - 0.0057 16.2 0.0 0.059 12.9 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 GAM27052.1 - 0.052 12.8 0.1 6.8 5.9 0.0 2.8 2 1 1 3 3 3 0 RIO1 family Fructosamin_kin PF03881.9 GAM27052.1 - 0.077 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase DUF1237 PF06824.6 GAM27053.1 - 0.05 12.2 0.0 0.066 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1237) KA1 PF02149.14 GAM27054.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase associated domain 1 DUF4002 PF13164.1 GAM27054.1 - 0.4 10.6 3.8 0.28 11.2 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4002) DUF1768 PF08719.6 GAM27056.1 - 6.6e-41 139.6 0.0 8.6e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) WD40 PF00400.27 GAM27057.1 - 5.2e-72 235.3 21.3 4e-14 51.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM27057.1 - 2.8e-12 46.7 0.9 9.2e-06 25.4 0.0 3.9 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM27057.1 - 6.4e-08 31.1 4.0 0.044 11.9 0.0 4.4 1 1 3 4 4 4 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 GAM27057.1 - 4e-06 25.3 0.0 3e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 GAM27057.1 - 8.2e-05 21.0 1.1 0.39 8.9 0.0 3.2 1 1 1 3 3 3 3 Cytochrome D1 heme domain PQQ_2 PF13360.1 GAM27057.1 - 0.00018 21.0 0.5 0.3 10.5 0.0 3.1 3 1 0 3 3 3 2 PQQ-like domain Coatomer_WDAD PF04053.9 GAM27057.1 - 0.00021 20.2 1.3 0.074 11.8 0.1 2.6 1 1 1 2 2 2 2 Coatomer WD associated region Kelch_6 PF13964.1 GAM27057.1 - 0.00094 19.2 1.5 1.2 9.4 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Hira PF07569.6 GAM27057.1 - 0.0016 17.7 0.7 4.2 6.5 0.0 4.0 3 2 2 5 5 5 1 TUP1-like enhancer of split PD40 PF07676.7 GAM27057.1 - 0.0028 17.2 4.2 4.9 6.9 0.0 4.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 GAM27057.1 - 0.0086 15.0 0.1 11 4.8 0.0 3.2 1 1 0 3 3 3 1 Protein of unknown function (DUF1513) DUF4221 PF13970.1 GAM27057.1 - 0.011 15.1 0.5 2.4 7.4 0.0 3.5 1 1 2 4 4 4 0 Domain of unknown function (DUF4221) Sas10_Utp3 PF04000.10 GAM27058.1 - 2.2e-15 56.6 0.4 3.5e-15 55.9 0.0 1.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.3 GAM27058.1 - 0.041 12.4 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF739 PF05339.6 GAM27059.1 - 0.0059 16.4 0.4 0.64 9.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF739) zf-4CXXC_R1 PF10497.4 GAM27060.1 - 4.5e-08 33.1 16.0 8.6e-08 32.2 11.1 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.1 GAM27060.1 - 0.21 11.4 8.5 0.51 10.1 5.9 1.7 1 0 0 1 1 1 0 Ring finger domain PhoPQ_related PF10142.4 GAM27061.1 - 1.4e-60 204.6 0.1 1.8e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 GAM27061.1 - 0.0029 17.3 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_11 PF13414.1 GAM27062.1 - 6.1e-69 227.6 27.5 4.1e-19 68.0 0.3 6.2 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 GAM27062.1 - 7.3e-51 167.7 27.5 1.6e-07 30.5 0.3 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 GAM27062.1 - 3.9e-44 145.0 22.7 2.4e-06 27.0 0.3 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 GAM27062.1 - 2.9e-27 94.7 7.9 1.1e-06 29.1 0.6 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 GAM27062.1 - 4.8e-27 93.7 17.5 3.3e-10 39.7 1.1 6.4 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 GAM27062.1 - 6.9e-22 75.5 19.8 0.00055 19.5 0.5 9.0 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 GAM27062.1 - 1e-19 69.2 2.9 0.0036 17.8 0.0 8.5 4 3 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM27062.1 - 4.6e-19 66.9 19.3 0.00013 21.8 0.1 8.2 9 0 0 9 9 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 GAM27062.1 - 5.5e-18 65.0 12.1 2.8e-06 27.5 0.4 6.5 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 GAM27062.1 - 1e-16 59.3 8.9 0.17 11.7 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 GAM27062.1 - 4.6e-11 42.7 14.1 0.00064 19.8 1.5 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 GAM27062.1 - 6.8e-11 41.8 7.6 0.0056 16.5 0.0 6.2 6 0 0 6 6 6 3 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 GAM27062.1 - 2.9e-09 36.6 0.3 0.15 11.9 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 GAM27062.1 - 0.00031 20.9 13.4 3.7 8.2 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM27062.1 - 0.00055 19.9 4.7 1 9.5 0.1 4.2 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF627 PF04781.7 GAM27062.1 - 0.001 18.6 0.1 2.3 7.8 0.0 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF627) TPR_10 PF13374.1 GAM27062.1 - 0.0025 17.6 10.2 0.94 9.4 0.1 7.1 9 0 0 9 9 9 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAM27062.1 - 0.0039 17.4 7.9 0.23 11.6 0.3 4.1 2 1 1 4 4 4 1 Alkyl sulfatase dimerisation MIT PF04212.13 GAM27062.1 - 0.0092 15.8 14.6 7.9 6.4 0.1 7.0 5 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 GAM27062.1 - 0.01 15.0 2.1 63 2.9 0.0 5.6 7 0 0 7 7 7 0 SHNi-TPR TPR_21 PF09976.4 GAM27062.1 - 0.022 14.7 0.7 0.022 14.7 0.5 4.2 2 2 1 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 GAM27062.1 - 0.044 12.5 3.9 10 4.7 0.1 3.1 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF357 PF04010.8 GAM27062.1 - 0.1 12.2 1.1 0.69 9.6 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF357) TPR_3 PF07720.7 GAM27062.1 - 0.34 10.7 5.6 0.96 9.3 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 GAM27062.1 - 0.37 10.1 12.9 0.82 9.0 0.8 4.6 4 1 1 5 5 5 0 26S proteasome subunit RPN7 TOM20_plant PF06552.7 GAM27062.1 - 0.93 9.0 9.6 8.4 5.9 0.1 4.7 3 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2225 PF09986.4 GAM27062.1 - 4.4 6.6 14.4 11 5.3 7.0 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Apc15p PF05841.6 GAM27063.1 - 0.1 13.3 1.8 0.2 12.4 1.3 1.4 1 0 0 1 1 1 0 Apc15p protein CH PF00307.26 GAM27064.1 - 2.3e-54 182.0 3.0 2.6e-17 62.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM27064.1 - 6.9e-11 41.6 0.8 0.1 12.2 0.1 4.5 4 0 0 4 4 4 4 CAMSAP CH domain EF-hand_1 PF00036.27 GAM27064.1 - 2e-10 39.1 1.6 1.8e-05 23.7 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 GAM27064.1 - 7.1e-10 38.3 0.4 0.00056 19.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM27064.1 - 2.7e-08 33.0 0.6 0.014 15.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAM27064.1 - 5.6e-08 32.7 0.3 2.2e-07 30.9 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM27064.1 - 2.8e-06 26.4 2.3 0.0058 15.9 0.0 3.0 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.13 GAM27064.1 - 0.057 13.1 0.5 0.19 11.4 0.3 2.0 1 0 0 1 1 1 0 Dockerin type I repeat DDE_Tnp_4 PF13359.1 GAM27066.1 - 6.7e-18 64.7 0.0 9.3e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM27066.1 - 1e-07 31.7 0.1 2.9e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Transposase DDE domain DUF1835 PF08874.5 GAM27067.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) TPR_19 PF14559.1 GAM27068.1 - 0.00048 20.4 0.0 1.9 8.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 GAM27068.1 - 0.023 14.6 0.1 1.7 8.8 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.9 GAM27068.1 - 0.035 14.5 1.0 26 5.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 GAM27068.1 - 0.056 13.4 0.0 8.2 6.4 0.0 3.2 2 0 0 2 2 2 0 PPR repeat family PI3Ka PF00613.15 GAM27069.1 - 2.1e-51 173.7 2.2 5.7e-51 172.3 1.5 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM27069.1 - 3.2e-42 144.6 0.0 1e-41 142.9 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM27069.1 - 2e-14 53.5 0.1 4.6e-14 52.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HEAT_2 PF13646.1 GAM27069.1 - 0.027 14.7 0.6 0.14 12.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats ACCA PF03255.9 GAM27069.1 - 1.6 8.2 8.7 4.8 6.7 0.8 3.0 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit dCMP_cyt_deam_1 PF00383.17 GAM27070.1 - 5.5e-13 48.4 0.0 1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Kua-UEV1_localn PF10520.4 GAM27070.1 - 0.28 10.8 2.8 0.42 10.2 0.1 2.1 2 0 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF4045 PF13254.1 GAM27072.1 - 0.37 10.0 17.3 0.39 9.9 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DHHW PF14286.1 GAM27072.1 - 0.47 9.7 10.8 0.48 9.6 7.5 1.0 1 0 0 1 1 1 0 DHHW protein GAGA_bind PF06217.7 GAM27072.1 - 0.47 10.3 13.6 0.46 10.4 9.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Pox_Ag35 PF03286.9 GAM27072.1 - 0.47 9.9 24.5 1.1 8.7 16.9 1.6 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 GAM27072.1 - 0.58 9.5 22.2 0.6 9.5 15.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO eIF-3c_N PF05470.7 GAM27072.1 - 0.87 7.5 17.0 0.92 7.5 11.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2413 PF10310.4 GAM27072.1 - 1 8.0 19.9 1.1 8.0 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3807 PF12720.2 GAM27072.1 - 1.1 9.4 17.7 1.1 9.3 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.7 GAM27072.1 - 1.1 9.0 20.9 1.2 8.9 14.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 GAM27072.1 - 1.3 7.5 15.7 1.4 7.4 10.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3827 PF12877.2 GAM27072.1 - 1.5 6.8 12.4 1.6 6.7 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) PLRV_ORF5 PF01690.12 GAM27072.1 - 2.2 7.3 13.2 2.2 7.3 9.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDHD PF02862.12 GAM27072.1 - 2.3 7.9 12.8 2.7 7.7 8.9 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 GAM27072.1 - 2.6 7.8 10.1 3.6 7.4 7.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.1 GAM27072.1 - 2.7 6.4 11.4 2.7 6.4 7.9 1.0 1 0 0 1 1 1 0 Raftlin Serinc PF03348.10 GAM27072.1 - 2.7 6.6 4.2 3.1 6.4 2.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF966 PF06136.8 GAM27072.1 - 2.8 7.2 12.7 2.7 7.3 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 GAM27072.1 - 4.1 4.9 12.1 4 4.9 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 GAM27072.1 - 4.3 6.2 8.5 4.9 6.0 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ARHGEF5_35 PF15441.1 GAM27072.1 - 5.1 5.7 19.4 6.5 5.4 13.4 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Vfa1 PF08432.5 GAM27072.1 - 5.5 6.9 26.5 6.5 6.7 18.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 GAM27072.1 - 6.3 5.8 10.9 7 5.7 7.5 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain eIF-4B PF06273.6 GAM27072.1 - 6.3 5.4 16.0 7 5.2 11.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Daxx PF03344.10 GAM27072.1 - 6.6 5.0 18.4 7.2 4.9 12.7 1.1 1 0 0 1 1 1 0 Daxx Family SOBP PF15279.1 GAM27072.1 - 7 6.9 7.6 6.9 6.9 5.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein CRT10 PF08728.5 GAM27072.1 - 7.2 4.4 8.5 7.4 4.4 5.9 1.1 1 0 0 1 1 1 0 CRT10 AAA_11 PF13086.1 GAM27072.1 - 8.1 5.9 9.6 9.5 5.7 6.6 1.1 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.7 GAM27072.1 - 8.3 4.1 24.3 10 3.8 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family Med12-LCEWAV PF12145.3 GAM27072.1 - 9.5 4.5 12.3 10 4.4 8.5 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Utp12 PF04003.7 GAM27073.1 - 1.9e-10 40.6 2.1 4e-10 39.5 1.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 GAM27073.1 - 1e-08 34.7 0.8 0.00059 19.6 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat DSPc PF00782.15 GAM27074.1 - 5.5e-29 100.4 0.1 8.7e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM27074.1 - 0.00019 20.8 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAM27074.1 - 0.074 13.0 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate NAD_binding_4 PF07993.7 GAM27074.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein HeH PF12949.2 GAM27075.1 - 4.9e-07 29.1 0.2 1.1e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain SWIB PF02201.13 GAM27075.1 - 0.046 13.4 0.3 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 SWIB/MDM2 domain DUF241 PF03087.9 GAM27075.1 - 3.4 7.0 9.6 0.35 10.3 0.7 2.5 1 1 1 2 2 2 0 Arabidopsis protein of unknown function FNIP PF05725.7 GAM27076.1 - 1e-101 332.6 72.6 3.8e-13 49.1 0.1 12.2 3 2 16 19 19 19 18 FNIP Repeat zf-RING_2 PF13639.1 GAM27077.1 - 2e-06 27.5 7.9 5e-06 26.2 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 GAM27077.1 - 4.1e-06 26.6 6.2 1.3e-05 25.0 4.3 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 GAM27077.1 - 1.1e-05 25.4 5.7 2.8e-05 24.1 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 GAM27077.1 - 0.00042 20.1 5.1 0.0015 18.3 3.5 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HEAT PF02985.17 GAM27077.1 - 0.0034 17.3 0.0 0.16 12.1 0.0 3.5 2 0 0 2 2 2 1 HEAT repeat RINGv PF12906.2 GAM27077.1 - 0.025 14.6 6.4 0.064 13.3 4.4 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 GAM27077.1 - 0.028 14.0 9.9 0.083 12.5 6.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 GAM27077.1 - 0.031 13.9 7.1 0.028 14.1 3.8 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 GAM27077.1 - 0.048 13.6 13.9 0.014 15.3 7.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 GAM27077.1 - 0.35 10.9 6.4 0.79 9.7 4.4 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3Hc3H PF13891.1 GAM27078.1 - 6.7e-06 26.0 6.4 1.4e-05 25.0 4.5 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-primase PF09329.6 GAM27078.1 - 0.00022 20.7 1.6 0.00022 20.7 1.1 3.3 3 0 0 3 3 3 1 Primase zinc finger INTS2 PF14750.1 GAM27079.1 - 1.1e-144 483.5 28.7 2.7e-141 472.2 17.9 2.3 2 0 0 2 2 2 2 Integrator complex subunit 2 FNIP PF05725.7 GAM27080.1 - 2.9e-22 78.3 17.8 4.3e-05 23.3 0.0 7.6 7 2 0 7 7 7 5 FNIP Repeat Cyclin_N PF00134.18 GAM27081.1 - 4.7e-08 32.6 0.5 9.8e-08 31.6 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain RNase_HII PF01351.13 GAM27082.1 - 1.9e-24 86.4 0.0 2.4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII adh_short PF00106.20 GAM27083.1 - 1.9e-16 60.4 0.0 3.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM27083.1 - 3e-07 30.2 0.0 4.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 GAM27083.1 - 0.00045 20.2 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 GAM27083.1 - 0.00097 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM27083.1 - 0.0093 15.4 0.0 0.013 14.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rad10 PF03834.9 GAM27084.1 - 9.9e-07 28.3 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 GAM27084.1 - 9.1e-06 25.7 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Transposase_20 PF02371.11 GAM27084.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family DMAP1 PF05499.7 GAM27084.1 - 0.11 12.0 0.7 0.2 11.1 0.1 1.7 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Mcm10 PF09332.6 GAM27084.1 - 5.3 6.3 8.2 34 3.6 4.4 2.2 2 0 0 2 2 2 0 Mcm10 replication factor Peptidase_S64 PF08192.6 GAM27084.1 - 6.2 5.0 14.9 10 4.2 10.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Zip PF02535.17 GAM27086.1 - 0.0096 14.9 0.0 0.061 12.3 0.0 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Ank_2 PF12796.2 GAM27087.1 - 4.4e-11 42.9 6.8 0.075 13.3 0.0 5.6 4 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM27087.1 - 8.8e-05 22.9 14.9 0.51 10.9 0.0 6.6 6 2 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM27087.1 - 0.1 12.4 11.8 22 5.0 0.0 7.6 9 1 0 9 9 9 0 Ankyrin repeat Ank_3 PF13606.1 GAM27087.1 - 1.4 9.3 21.7 26 5.4 0.0 9.1 13 0 0 13 13 13 0 Ankyrin repeat SCAMP PF04144.8 GAM27088.1 - 3.8e-27 95.3 12.1 5e-27 94.9 8.4 1.1 1 0 0 1 1 1 1 SCAMP family DUF4190 PF13828.1 GAM27088.1 - 0.018 14.5 7.1 0.02 14.4 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4190) F-box-like PF12937.2 GAM27089.1 - 8.4e-11 41.4 0.2 2.5e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM27089.1 - 9.7e-07 28.2 1.2 2.1e-06 27.2 0.4 1.9 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 GAM27089.1 - 0.00025 20.7 0.3 0.00083 19.0 0.1 1.9 1 1 0 1 1 1 1 F-box-like domain Nop14 PF04147.7 GAM27089.1 - 0.012 13.6 7.4 0.016 13.1 5.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 GAM27089.1 - 0.035 13.3 3.8 0.048 12.8 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Osteopontin PF00865.13 GAM27089.1 - 0.036 13.3 14.6 0.056 12.6 10.1 1.2 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.9 GAM27089.1 - 0.096 10.7 9.2 0.14 10.2 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 GAM27089.1 - 0.15 10.2 5.6 0.19 9.9 3.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor YL1 PF05764.8 GAM27089.1 - 0.39 10.2 8.5 0.63 9.6 5.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.4 GAM27089.1 - 1.6 7.3 15.1 2.3 6.8 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 GAM27089.1 - 3.9 6.6 12.3 5.9 6.0 8.5 1.2 1 0 0 1 1 1 0 SDA1 bZIP_1 PF00170.16 GAM27090.1 - 6.6e-11 42.0 17.8 2.6e-10 40.1 8.7 3.1 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.10 GAM27090.1 - 1.6e-07 31.0 9.0 1.6e-07 31.0 6.2 4.1 3 2 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.12 GAM27090.1 - 0.0018 18.5 7.9 0.0018 18.5 5.5 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor HALZ PF02183.13 GAM27090.1 - 0.0099 15.5 0.4 0.0099 15.5 0.3 2.5 2 1 0 2 2 2 1 Homeobox associated leucine zipper RasGAP_C PF03836.10 GAM27090.1 - 0.81 9.3 18.0 2.8 7.6 1.5 2.7 2 1 0 2 2 2 0 RasGAP C-terminus CENP-F_leu_zip PF10473.4 GAM27090.1 - 0.99 9.2 14.5 0.22 11.3 2.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 GAM27090.1 - 2.5 8.0 7.6 0.52 10.2 1.0 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-CCHC PF00098.18 GAM27091.1 - 6.1e-35 117.5 40.8 4.6e-09 35.7 2.6 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 GAM27091.1 - 2e-07 30.5 25.5 0.042 13.5 0.4 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 GAM27091.1 - 0.0043 16.7 33.7 0.29 10.9 0.7 5.0 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.1 GAM27091.1 - 0.0087 15.5 25.6 0.14 11.6 1.4 4.4 4 0 0 4 4 4 3 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.1 GAM27091.1 - 0.012 15.2 2.0 0.012 15.2 1.4 4.5 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.1 GAM27091.1 - 0.014 14.8 0.9 0.014 14.8 0.6 5.1 3 2 2 5 5 5 0 Zinc knuckle Rpr2 PF04032.11 GAM27092.1 - 9.4e-10 38.2 1.6 3.6e-09 36.3 1.1 2.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain BAR PF03114.13 GAM27093.1 - 6.5e-23 81.4 7.4 1.2e-22 80.6 5.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 GAM27093.1 - 5.3e-16 57.9 0.0 1.8e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 GAM27093.1 - 1.8e-13 49.6 0.0 9.2e-13 47.3 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 GAM27093.1 - 3.7e-09 35.9 0.0 8.9e-09 34.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Synaptonemal_3 PF15191.1 GAM27093.1 - 0.0015 18.2 1.5 0.0036 16.9 1.0 1.6 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 NPHI_C PF08469.5 GAM27093.1 - 0.014 15.2 0.2 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal LOH1CR12 PF10158.4 GAM27093.1 - 0.015 15.0 1.2 0.032 14.0 0.6 1.8 1 1 0 1 1 1 0 Tumour suppressor protein DUF3156 PF11354.3 GAM27093.1 - 0.026 13.8 0.1 0.067 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3156) DUF342 PF03961.8 GAM27093.1 - 1.1 7.5 7.4 11 4.2 5.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Bacillus_HBL PF05791.6 GAM27093.1 - 1.8 7.9 8.9 0.3 10.4 1.6 2.8 1 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) RQC PF09382.5 GAM27094.1 - 5.4e-19 67.8 0.3 1.3e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 GAM27094.1 - 3.4e-18 65.2 0.0 1.4e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM27094.1 - 2.9e-15 56.1 0.0 2.6e-13 49.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 GAM27094.1 - 3.2e-14 52.3 0.1 6.8e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 HRDC domain DUF3439 PF11921.3 GAM27094.1 - 0.065 12.9 3.5 0.16 11.6 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM27094.1 - 2.4 6.0 8.5 3.8 5.3 5.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CobU PF02283.11 GAM27095.1 - 0.036 13.4 0.6 0.4 10.0 0.0 2.6 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Arm PF00514.18 GAM27095.1 - 0.27 11.1 7.7 19 5.2 0.0 6.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Desmo_N PF06771.6 GAM27095.1 - 1.1 9.2 6.1 30 4.6 0.1 4.0 2 1 1 3 3 3 0 Viral Desmoplakin N-terminus Cna_B PF05738.8 GAM27096.1 - 2.6e-43 145.6 46.9 4e-06 26.4 0.1 14.1 14 0 0 14 14 14 11 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM27096.1 - 9.7e-29 99.2 95.6 6.7e-05 22.8 0.0 17.3 13 4 5 18 18 18 11 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 GAM27096.1 - 9.3e-26 90.0 0.1 0.38 10.5 0.0 12.2 12 0 0 12 12 12 8 Protein of unknown function (DUF2012) FlgD_ig PF13860.1 GAM27096.1 - 7.2e-22 76.9 29.3 0.0073 16.0 0.1 13.2 11 2 0 11 11 11 8 FlgD Ig-like domain Y_Y_Y PF07495.8 GAM27096.1 - 8.9e-05 22.1 11.9 10 5.9 0.0 9.4 12 0 0 12 12 12 1 Y_Y_Y domain TPR_11 PF13414.1 GAM27097.1 - 0.00025 20.6 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 TPR repeat WW PF00397.21 GAM27097.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 WW domain TPR_1 PF00515.23 GAM27097.1 - 0.023 14.2 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM27097.1 - 0.039 13.8 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3391 PF11871.3 GAM27097.1 - 0.093 12.9 0.1 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PB1 PF00564.19 GAM27097.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 PB1 domain DSPc PF00782.15 GAM27099.1 - 2.5e-07 30.3 0.1 7.2e-07 28.8 0.1 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM27099.1 - 3.8e-06 26.4 0.0 5.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM27099.1 - 0.00011 22.4 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM27099.1 - 0.003 17.6 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF1122 PF06557.6 GAM27099.1 - 0.014 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) PTEN_C2 PF10409.4 GAM27100.1 - 1.1e-06 28.3 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DNA_pol_B_palm PF14792.1 GAM27101.1 - 6.3e-30 103.5 0.1 1.3e-29 102.4 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 GAM27101.1 - 3.7e-21 74.5 0.0 7.3e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 GAM27101.1 - 1.7e-16 60.1 0.2 1.9e-15 56.7 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 GAM27101.1 - 2e-16 59.2 0.2 4.8e-16 58.0 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 GAM27101.1 - 0.0013 18.8 0.6 0.0062 16.6 0.2 2.2 1 1 2 3 3 3 3 Helix-hairpin-helix domain DUF3824 PF12868.2 GAM27101.1 - 0.89 10.4 4.1 0.56 11.1 1.5 1.6 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Nbl1_Borealin_N PF10444.4 GAM27102.1 - 0.078 12.3 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal FNIP PF05725.7 GAM27103.1 - 3.9e-15 55.5 24.6 4.1e-06 26.6 0.3 7.0 6 1 1 7 7 7 5 FNIP Repeat Mannosyl_trans2 PF04188.8 GAM27104.1 - 5.4e-77 259.5 37.3 6.9e-42 143.8 8.7 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V)) TIG PF01833.19 GAM27105.1 - 5e-17 61.6 35.6 4.4e-07 29.7 1.7 6.2 3 2 3 6 6 6 5 IPT/TIG domain Rifin_STEVOR PF02009.11 GAM27105.1 - 0.19 11.3 1.6 0.29 10.7 1.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family FNIP PF05725.7 GAM27106.1 - 2.4e-78 257.8 23.6 4e-15 55.4 0.6 8.1 5 2 0 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 GAM27106.1 - 0.17 11.8 12.9 13 5.8 0.1 6.8 4 4 5 9 9 9 0 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM27107.1 - 2.5e-45 152.1 4.2 3.1e-13 49.4 0.0 5.6 3 2 1 6 6 6 5 FNIP Repeat LRR_5 PF13306.1 GAM27107.1 - 0.024 14.3 0.0 0.24 11.0 0.0 2.5 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) NSP13 PF06460.7 GAM27107.1 - 0.028 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 Glyco_transf_10 PF00852.14 GAM27108.1 - 3e-50 170.7 0.1 3.9e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Arf PF00025.16 GAM27109.1 - 2.2e-59 199.6 0.0 3.1e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 GAM27109.1 - 8.8e-12 44.6 0.0 1.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27109.1 - 2.3e-11 44.2 0.0 4.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 GAM27109.1 - 1.1e-10 41.0 0.0 1.6e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM27109.1 - 1.9e-08 33.7 0.0 2.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 GAM27109.1 - 4.3e-07 28.9 12.8 5e-06 25.4 0.0 3.3 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.18 GAM27109.1 - 2.4e-05 24.2 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 GAM27109.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ACT PF01842.20 GAM27109.1 - 0.092 12.2 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain ABC_tran PF00005.22 GAM27109.1 - 0.22 11.7 1.2 0.24 11.7 0.1 1.8 2 1 0 2 2 2 0 ABC transporter DUF605 PF04652.11 GAM27109.1 - 5.1 6.3 22.9 6.3 6.0 15.9 1.1 1 0 0 1 1 1 0 Vta1 like RhoGAP PF00620.22 GAM27110.1 - 2.7e-39 134.2 0.2 7.4e-39 132.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LRR_6 PF13516.1 GAM27110.1 - 1.2e-10 40.3 32.9 0.049 13.7 0.1 9.4 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 GAM27110.1 - 4.6e-05 22.9 14.8 2.1 8.0 0.0 6.1 4 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM27110.1 - 5e-05 22.7 7.2 5.5 7.4 0.0 7.1 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.1 GAM27110.1 - 0.011 15.4 14.7 0.26 11.0 0.1 5.7 4 1 1 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 GAM27110.1 - 0.22 11.8 11.9 16 6.2 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat Ribosomal_S4 PF00163.14 GAM27112.1 - 3.8e-26 91.3 1.8 7.5e-26 90.3 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAM27112.1 - 3.2e-11 42.4 0.5 9.6e-11 40.9 0.3 1.9 1 0 0 1 1 1 1 S4 domain Peptidase_M66 PF10462.4 GAM27113.1 - 4.4e-49 166.9 0.0 6.5e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM27113.1 - 0.012 16.0 0.1 0.049 14.1 0.0 2.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like fn3 PF00041.16 GAM27115.1 - 5.5e-07 29.6 16.0 0.0032 17.5 0.2 4.8 5 0 0 5 5 5 3 Fibronectin type III domain EB PF01683.13 GAM27115.1 - 0.19 11.8 7.8 0.12 12.4 2.0 3.0 3 0 0 3 3 3 0 EB module EGF_2 PF07974.8 GAM27115.1 - 0.91 9.7 19.5 0.11 12.6 9.7 2.5 2 0 0 2 2 2 0 EGF-like domain FPL PF09758.4 GAM27116.1 - 6.3e-58 194.7 12.2 6.3e-58 194.7 8.4 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein DUF3439 PF11921.3 GAM27116.1 - 0.2 11.4 11.0 0.58 9.9 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_6 PF14259.1 GAM27117.1 - 2.3e-28 97.9 1.8 5.2e-16 58.3 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM27117.1 - 2.4e-27 94.3 3.5 1.4e-15 56.6 0.2 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27117.1 - 6.8e-13 48.2 1.6 9e-05 22.2 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 GAM27117.1 - 0.00018 21.1 0.1 0.83 9.4 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 GAM27117.1 - 0.037 13.7 0.3 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Cellulose_synt PF03552.9 GAM27117.1 - 7 4.8 5.2 13 3.9 3.6 1.4 1 0 0 1 1 1 0 Cellulose synthase DUF202 PF02656.10 GAM27118.1 - 3.4e-08 33.6 5.7 3.4e-08 33.6 3.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LMBR1 PF04791.11 GAM27118.1 - 0.0026 16.4 0.7 0.0054 15.3 0.0 1.9 1 1 1 2 2 2 1 LMBR1-like membrane protein DUF3439 PF11921.3 GAM27118.1 - 0.091 12.5 2.0 0.17 11.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4234 PF14018.1 GAM27118.1 - 0.16 11.7 2.0 0.36 10.5 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Mucin PF01456.12 GAM27118.1 - 0.32 10.7 10.2 0.062 13.0 1.7 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein CDC27 PF09507.5 GAM27118.1 - 0.39 9.8 56.5 0.68 9.0 39.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RasGAP PF00616.14 GAM27119.1 - 1.1e-33 116.6 0.8 6.6e-33 114.0 0.0 2.6 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 GAM27119.1 - 2.4e-17 63.1 2.2 5.3e-17 62.0 1.5 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 GAM27119.1 - 2.5e-13 49.7 2.0 5.1e-13 48.8 1.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.8 GAM27119.1 - 0.00094 18.5 1.5 0.26 10.5 0.3 2.4 2 0 0 2 2 2 2 Myosin tail ABC2_membrane_3 PF12698.2 GAM27119.1 - 0.12 11.4 0.4 0.24 10.3 0.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Ras PF00071.17 GAM27120.1 - 6.3e-58 194.7 0.5 7.4e-58 194.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27120.1 - 1.5e-18 67.3 0.0 2.4e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27120.1 - 3.4e-16 58.9 0.1 4.1e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM27120.1 - 1.9e-10 40.3 0.5 2.3e-10 39.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM27120.1 - 8.9e-07 28.5 0.3 2.8e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM27120.1 - 2e-06 27.7 0.1 6.6e-06 26.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM27120.1 - 2.5e-05 23.6 0.2 0.00012 21.3 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 GAM27120.1 - 0.00041 19.6 0.1 0.00052 19.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CPT PF07931.7 GAM27120.1 - 0.058 13.0 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Vma12 PF11712.3 GAM27121.1 - 1.4e-15 57.2 1.5 1.7e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TMEM51 PF15345.1 GAM27121.1 - 0.016 14.9 2.5 1 8.9 1.4 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 PMT PF02366.13 GAM27121.1 - 0.068 12.5 0.2 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase TFIIA_gamma_C PF02751.9 GAM27121.1 - 0.11 12.3 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit Strabismus PF06638.6 GAM27122.1 - 4.1 5.6 6.1 6 5.0 4.2 1.2 1 0 0 1 1 1 0 Strabismus protein DUF3975 PF13126.1 GAM27122.1 - 4.1 7.6 9.2 0.58 10.3 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3975) Intg_mem_TP0381 PF09529.5 GAM27122.1 - 4.5 6.4 20.5 0.032 13.4 6.1 2.3 1 1 1 2 2 2 0 Integral membrane protein (intg_mem_TP0381) DUF1084 PF06454.6 GAM27123.1 - 0.032 13.2 0.3 0.04 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) TFIIB PF00382.14 GAM27124.1 - 2.9e-42 142.3 0.3 2.4e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 GAM27124.1 - 2.2e-15 55.6 2.7 3.7e-15 54.9 1.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 GAM27124.1 - 2.4e-06 27.4 0.6 0.059 13.2 0.0 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain HTH_11 PF08279.7 GAM27124.1 - 0.021 14.4 0.1 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 HTH domain eIF-5_eIF-2B PF01873.12 GAM27124.1 - 0.025 14.2 0.2 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Cyclin_N PF00134.18 GAM27124.1 - 0.042 13.4 0.1 0.66 9.5 0.0 2.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain HTH_Tnp_ISL3 PF13542.1 GAM27124.1 - 0.047 12.8 0.0 0.13 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 zf-ribbon_3 PF13248.1 GAM27124.1 - 0.062 12.5 0.5 0.14 11.4 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain ORC6 PF05460.8 GAM27124.1 - 0.068 12.2 1.0 0.21 10.6 0.6 1.7 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) zf-FPG_IleRS PF06827.9 GAM27124.1 - 0.09 12.4 1.2 0.22 11.2 0.9 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Prim_Zn_Ribbon PF08273.7 GAM27124.1 - 0.58 10.2 2.3 2 8.5 1.6 1.9 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Kelch_6 PF13964.1 GAM27125.1 - 4.5e-11 42.4 2.5 0.0071 16.4 0.0 4.6 2 1 2 4 4 4 3 Kelch motif Kelch_4 PF13418.1 GAM27125.1 - 2.7e-05 23.8 5.4 0.00032 20.3 0.1 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM27125.1 - 0.00064 19.8 1.8 0.034 14.3 0.0 3.6 2 1 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM27125.1 - 0.0024 17.3 3.2 0.015 14.8 0.0 2.8 3 0 0 3 3 3 1 Kelch motif Alpha-2-MRAP_C PF06401.6 GAM27125.1 - 0.01 15.7 1.5 0.01 15.7 1.0 2.3 2 1 1 3 3 3 0 Alpha-2-macroglobulin RAP, C-terminal domain Baculo_PEP_C PF04513.7 GAM27125.1 - 0.022 14.5 1.2 0.022 14.5 0.8 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_5 PF13854.1 GAM27125.1 - 0.19 11.7 0.1 0.19 11.7 0.1 3.5 5 0 0 5 5 5 0 Kelch motif DUF1687 PF07955.6 GAM27125.1 - 1.4 8.8 6.9 0.34 10.8 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1687) BBP1_N PF15271.1 GAM27125.1 - 2.9 8.2 9.6 1.2 9.4 0.3 2.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein zf-B_box PF00643.19 GAM27126.1 - 3.6e-06 26.7 2.3 7.7e-06 25.7 1.6 1.6 1 0 0 1 1 1 1 B-box zinc finger Baculo_PEP_C PF04513.7 GAM27126.1 - 0.0086 15.9 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 GAM27126.1 - 0.069 12.9 0.8 0.94 9.2 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II IBR PF01485.16 GAM27126.1 - 0.29 11.0 5.4 0.18 11.6 1.9 2.0 1 1 1 2 2 2 0 IBR domain 3HCDH_N PF02737.13 GAM27127.1 - 5.1e-63 211.9 2.5 6.2e-63 211.6 1.7 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 GAM27127.1 - 8.2e-36 122.3 0.0 1.8e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 GAM27127.1 - 7.5e-06 25.7 1.4 1.2e-05 25.0 0.7 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 GAM27127.1 - 2.2e-05 24.3 1.1 5.1e-05 23.1 0.7 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 GAM27127.1 - 3.6e-05 23.8 1.7 8.4e-05 22.6 0.8 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 GAM27127.1 - 8.5e-05 22.5 0.2 0.00019 21.4 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 GAM27127.1 - 0.00011 22.5 1.3 0.00027 21.3 0.9 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 GAM27127.1 - 0.00023 20.3 0.2 0.00027 20.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 GAM27127.1 - 0.0003 20.2 0.4 0.00044 19.6 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 GAM27127.1 - 0.0021 17.2 0.1 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAM27127.1 - 0.003 17.7 0.5 0.0053 17.0 0.3 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding ApbA PF02558.11 GAM27127.1 - 0.0033 16.8 0.1 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_18 PF12847.2 GAM27127.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ELFV_dehydrog PF00208.16 GAM27127.1 - 0.014 14.9 0.3 0.021 14.4 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAO PF01266.19 GAM27127.1 - 0.021 13.7 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase KR PF08659.5 GAM27127.1 - 0.028 14.0 0.1 0.042 13.5 0.1 1.2 1 0 0 1 1 1 0 KR domain Pyr_redox_3 PF13738.1 GAM27127.1 - 0.031 14.3 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 GAM27127.1 - 0.04 13.7 1.0 0.099 12.4 0.7 1.8 1 1 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 GAM27127.1 - 0.044 14.1 0.3 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DapB_N PF01113.15 GAM27127.1 - 0.045 13.6 1.7 0.1 12.5 1.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_25 PF13649.1 GAM27127.1 - 0.05 13.9 0.1 0.13 12.6 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Gp_dh_N PF00044.19 GAM27127.1 - 0.063 13.2 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 GAM27127.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Kelch_4 PF13418.1 GAM27128.1 - 4.6e-15 55.1 11.2 6.9e-08 32.1 0.0 5.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM27128.1 - 3.1e-12 46.0 13.7 0.00054 20.0 0.0 5.6 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.1 GAM27128.1 - 4e-09 36.3 2.9 0.00051 20.1 0.0 4.8 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM27128.1 - 7.1e-07 28.6 5.9 0.0026 17.2 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM27128.1 - 1.9e-05 24.5 12.9 0.084 12.8 0.1 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 GAM27128.1 - 2.6e-05 23.8 4.3 0.2 11.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif AUX_IAA PF02309.11 GAM27129.1 - 0.033 13.9 0.8 0.056 13.1 0.6 1.3 1 0 0 1 1 1 0 AUX/IAA family PP2C PF00481.16 GAM27130.1 - 6.2e-55 186.3 0.0 9.8e-39 133.2 0.0 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C SIN1 PF05422.7 GAM27130.1 - 0.0092 14.5 0.0 0.11 10.9 0.0 2.1 1 1 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) FGGY_C PF02782.11 GAM27131.1 - 1.1e-65 221.0 1.2 1.6e-65 220.4 0.4 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 GAM27131.1 - 3.5e-65 219.7 0.1 2.3e-32 112.2 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain IP_trans PF02121.13 GAM27132.1 - 3.1e-101 337.8 0.3 3.5e-101 337.6 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein F5_F8_type_C PF00754.20 GAM27133.1 - 0.073 12.9 0.1 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 F5/8 type C domain CTP_synth_N PF06418.9 GAM27134.1 - 2.7e-124 413.7 0.2 4.6e-124 412.9 0.2 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 GAM27134.1 - 2.7e-55 186.8 0.0 4.8e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 GAM27134.1 - 3.7e-05 23.2 2.1 0.00031 20.2 0.3 2.9 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 GAM27134.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pec_lyase_C PF00544.14 GAM27134.1 - 0.033 13.6 0.1 0.084 12.3 0.0 1.6 2 0 0 2 2 2 0 Pectate lyase DUF3719 PF12516.3 GAM27134.1 - 0.097 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) UcrQ PF02939.11 GAM27135.1 - 1e-11 44.4 0.3 1.1e-11 44.4 0.2 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 GAM27135.1 - 1.6e-05 24.9 0.0 1.9e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) DUF2141 PF09912.4 GAM27137.1 - 6e-13 48.4 10.5 0.79 9.3 0.0 11.5 14 0 0 14 14 14 6 Uncharacterized protein conserved in bacteria (DUF2141) Cna_B PF05738.8 GAM27137.1 - 2.7e-06 27.0 1.9 0.0002 21.0 0.0 17.0 15 4 3 18 18 18 4 Cna protein B-type domain DUF919 PF06034.6 GAM27137.1 - 1.4 8.6 7.0 1.1e+02 2.5 0.0 5.1 6 0 0 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF919) LRR_6 PF13516.1 GAM27138.1 - 5.4e-15 53.7 42.0 0.021 14.8 0.0 11.2 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 GAM27138.1 - 5.4e-07 29.0 39.6 0.094 12.3 0.0 7.3 3 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27138.1 - 0.0024 17.5 32.5 0.03 14.0 2.9 6.0 2 2 3 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 GAM27138.1 - 0.062 13.5 23.8 13 6.5 0.1 9.6 11 0 0 11 11 11 0 Leucine rich repeat LRR_1 PF00560.28 GAM27138.1 - 0.41 10.8 30.0 21 5.6 0.6 10.0 10 2 0 10 10 10 0 Leucine Rich Repeat Ras PF00071.17 GAM27139.1 - 9.2e-34 116.1 0.1 1.1e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27139.1 - 3e-14 53.5 0.0 4.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27139.1 - 9.3e-12 44.5 0.4 1.1e-11 44.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM27139.1 - 6.2e-07 29.3 0.1 8.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM27139.1 - 3e-06 26.7 0.2 3e-05 23.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM27139.1 - 0.00056 19.2 0.4 0.082 12.1 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF2057 PF09829.4 GAM27139.1 - 0.0016 18.1 0.2 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2057) PduV-EutP PF10662.4 GAM27139.1 - 0.0038 16.7 0.5 2.8 7.4 0.0 2.5 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 GAM27139.1 - 0.0052 15.9 0.0 0.0065 15.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region E1_dh PF00676.15 GAM27139.1 - 0.0063 15.2 0.2 0.012 14.4 0.0 1.4 2 0 0 2 2 2 1 Dehydrogenase E1 component AAA_24 PF13479.1 GAM27139.1 - 0.015 14.9 0.1 0.051 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 GAM27139.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 GAM27139.1 - 0.042 13.0 0.2 0.067 12.4 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 GAM27139.1 - 0.063 12.6 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 GAM27139.1 - 0.083 13.0 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 GAM27139.1 - 0.098 12.8 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA helicase HMG-CoA_red PF00368.13 GAM27140.1 - 6.5e-161 535.1 2.6 8.9e-161 534.6 1.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase WD40 PF00400.27 GAM27141.1 - 3.3e-39 131.3 20.1 2.8e-07 30.1 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 GAM27141.1 - 0.00047 18.4 4.8 0.56 8.2 0.1 4.6 1 1 4 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 GAM27141.1 - 0.00055 19.6 0.8 0.026 14.2 0.1 3.7 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF2509 PF10713.4 GAM27141.1 - 0.048 13.4 0.6 0.22 11.2 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2509) FA_FANCE PF11510.3 GAM27142.1 - 7.2e-12 44.9 5.9 1.3e-11 44.2 4.1 1.3 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE FNIP PF05725.7 GAM27143.1 - 2.6e-28 97.7 13.4 3.5e-10 39.6 0.0 6.4 3 2 4 7 7 7 7 FNIP Repeat PseudoU_synth_2 PF00849.17 GAM27144.1 - 3.7e-22 78.9 9.8 7.4e-21 74.6 1.7 4.1 2 1 0 2 2 2 1 RNA pseudouridylate synthase BUD22 PF09073.5 GAM27144.1 - 0.0003 19.9 13.9 0.0003 19.9 9.7 3.1 3 0 0 3 3 3 1 BUD22 S4 PF01479.20 GAM27144.1 - 0.0062 15.9 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 GAM27144.1 - 0.03 13.9 0.1 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 S4 domain Pkinase PF00069.20 GAM27145.1 - 1.3e-52 178.5 0.0 1.6e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27145.1 - 9.5e-51 172.3 0.0 1.2e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM27145.1 - 0.00055 19.7 0.0 0.0084 15.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Keratin_matx PF04579.7 GAM27145.1 - 0.044 14.0 0.2 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein Kdo PF06293.9 GAM27145.1 - 0.099 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 GAM27146.1 - 3.7e-37 127.2 0.0 4.7e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27146.1 - 4.4e-11 43.3 0.0 8.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 GAM27146.1 - 0.054 12.7 0.0 0.079 12.2 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Corona_RPol_N PF06478.8 GAM27146.1 - 0.096 11.3 0.2 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Coronavirus RPol N-terminus ARID PF01388.16 GAM27147.1 - 2.2e-27 94.7 0.4 2.4e-26 91.3 0.0 2.7 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.1 GAM27147.1 - 5.9e-12 45.2 0.9 1.2e-11 44.3 0.6 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 MAP65_ASE1 PF03999.7 GAM27147.1 - 0.0079 14.8 19.5 0.012 14.2 13.5 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Myb_DNA-bind_3 PF12776.2 GAM27147.1 - 6.5 7.4 6.5 7.9 7.1 3.2 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain FKBP_C PF00254.23 GAM27148.1 - 2.3e-26 91.6 0.0 8.3e-26 89.8 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FUSC PF04632.7 GAM27148.1 - 4.8 5.5 4.4 8.5 4.6 3.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Oxidored_FMN PF00724.15 GAM27149.1 - 7e-78 261.9 0.0 8.7e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Radical_SAM PF04055.16 GAM27150.1 - 6.8e-14 52.3 0.0 1.3e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 GAM27150.1 - 3.8e-05 23.6 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 GAM27150.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain XS PF03468.9 GAM27150.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 XS domain tRNA_anti-codon PF01336.20 GAM27151.1 - 0.019 14.7 0.2 0.043 13.6 0.1 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SnoaL_2 PF12680.2 GAM27152.1 - 0.031 14.6 0.0 0.049 14.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain FNIP PF05725.7 GAM27153.1 - 6e-45 150.9 15.7 3e-13 49.4 0.2 5.9 4 1 2 7 7 7 6 FNIP Repeat LRR_5 PF13306.1 GAM27153.1 - 0.0045 16.6 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) FNIP PF05725.7 GAM27154.1 - 2.6e-84 276.9 3.2 3.5e-14 52.4 0.3 8.1 7 1 0 8 8 8 7 FNIP Repeat FNIP PF05725.7 GAM27155.1 - 1.7e-70 232.7 14.7 2e-13 50.0 0.0 9.2 7 1 3 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 GAM27155.1 - 0.015 15.2 4.1 19 5.2 0.0 5.3 3 1 3 6 6 6 0 Protein of unknown function (DUF1769) LRR_4 PF12799.2 GAM27155.1 - 0.054 13.1 0.3 0.054 13.1 0.2 3.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 GAM27156.1 - 8.6e-95 310.4 1.5 2e-13 50.0 0.0 8.2 5 1 2 8 8 8 8 FNIP Repeat LRR_7 PF13504.1 GAM27156.1 - 7.9 7.1 12.4 12 6.6 0.2 6.2 9 0 0 9 9 9 0 Leucine rich repeat Cyt-b5 PF00173.23 GAM27157.1 - 9.7e-23 79.7 0.0 1.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Myotub-related PF06602.9 GAM27158.1 - 3.9e-105 351.5 0.1 3.9e-105 351.5 0.0 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 GAM27158.1 - 0.003 17.8 0.0 0.003 17.8 0.0 2.3 3 0 0 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 GAM27158.1 - 0.018 14.6 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF1179 PF06678.6 GAM27158.1 - 9.4 6.6 13.8 0.19 12.0 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Coiled PF05710.7 GAM27161.1 - 0.00046 20.6 6.2 0.0006 20.2 4.3 1.4 1 1 0 1 1 1 1 Coiled coil Tox-ART-HYD1 PF15633.1 GAM27162.1 - 1.1e-12 48.5 0.0 1.4e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 HYD1 signature containing ADP-ribosyltransferase PARP PF00644.15 GAM27162.1 - 0.085 12.2 0.1 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Coiled PF05710.7 GAM27163.1 - 0.0018 18.7 8.7 0.0023 18.3 6.0 1.4 1 1 0 1 1 1 1 Coiled coil Peptidase_M49 PF03571.10 GAM27164.1 - 4.9e-217 721.3 0.0 5.9e-217 721.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 BSP PF04450.7 GAM27165.1 - 9.2e-09 35.0 0.4 1.4e-08 34.4 0.3 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 GAM27165.1 - 9.3e-05 22.4 0.3 0.00016 21.7 0.2 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily CLIP PF12032.3 GAM27165.1 - 0.00041 20.3 70.0 1.3 9.1 1.1 9.3 9 0 0 9 9 9 7 Regulatory CLIP domain of proteinases Semenogelin PF05474.6 GAM27165.1 - 0.26 9.5 0.8 6 5.0 0.1 3.1 1 1 2 3 3 3 0 Semenogelin PAP2 PF01569.16 GAM27166.1 - 0.00014 21.5 0.5 0.00051 19.7 0.3 1.9 1 0 0 1 1 1 1 PAP2 superfamily BSP PF04450.7 GAM27167.1 - 4.5e-09 36.0 0.7 6.7e-09 35.5 0.5 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 GAM27167.1 - 0.0013 18.7 2.7 0.0013 18.7 1.9 2.2 1 1 1 2 2 2 1 Peptidase MA superfamily CfAFP PF05264.6 GAM27167.1 - 0.019 14.7 0.7 0.03 14.1 0.5 1.3 1 0 0 1 1 1 0 Choristoneura fumiferana antifreeze protein (CfAFP) DUF4419 PF14388.1 GAM27168.1 - 1e-97 326.9 1.9 1.5e-97 326.4 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) SHS2_Rpb7-N PF03876.12 GAM27169.1 - 0.0024 17.9 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 F_actin_cap_B PF01115.12 GAM27171.1 - 2.6e-103 344.4 0.0 3e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.12 GAM27171.1 - 0.0064 15.5 0.1 0.061 12.3 0.0 2.4 1 1 1 2 2 2 1 F-actin capping protein alpha subunit Pkinase PF00069.20 GAM27172.1 - 1.4e-77 260.3 0.0 2e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27172.1 - 2.6e-41 141.4 0.0 4e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 GAM27172.1 - 1.5e-07 30.6 0.1 3.5e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 GAM27172.1 - 1.6e-05 23.9 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAM27172.1 - 0.00023 20.5 0.7 0.00043 19.6 0.5 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM27172.1 - 0.0058 15.7 0.1 0.014 14.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM27172.1 - 0.0059 16.3 0.0 0.4 10.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM27172.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase PPR_2 PF13041.1 GAM27173.1 - 4.2e-07 29.8 5.3 0.29 11.1 0.0 7.1 7 0 0 7 7 7 2 PPR repeat family PPR_3 PF13812.1 GAM27173.1 - 1.9e-05 24.5 0.6 1.8 9.0 0.0 6.0 5 0 0 5 5 5 1 Pentatricopeptide repeat domain NACHT PF05729.7 GAM27173.1 - 0.0091 15.6 0.2 0.034 13.7 0.1 1.9 1 1 0 1 1 1 1 NACHT domain PPR PF01535.15 GAM27173.1 - 0.024 14.5 11.3 12 6.1 0.1 7.0 7 0 0 7 7 7 0 PPR repeat Ank_2 PF12796.2 GAM27174.1 - 4.8e-10 39.6 0.1 0.00073 19.8 0.0 5.4 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM27174.1 - 6.5e-05 23.3 3.8 5.3 7.6 0.0 6.6 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27174.1 - 0.00029 20.7 2.7 7.8 7.0 0.0 6.8 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.25 GAM27174.1 - 0.0018 17.9 3.2 3.4 7.6 0.1 5.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 GAM27174.1 - 0.0036 17.5 2.5 63 4.0 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM27174.1 - 0.031 14.0 4.5 0.38 10.5 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3447) PTPLA PF04387.9 GAM27175.1 - 3.6e-53 179.3 10.3 3.6e-53 179.3 7.2 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA NUP50 PF08911.6 GAM27176.1 - 3.5e-07 30.5 5.7 3.5e-07 30.5 4.0 4.5 4 2 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) zf-RanBP PF00641.13 GAM27176.1 - 1.2 8.3 37.2 0.94 8.6 5.4 3.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 GAM27176.1 - 2 8.0 19.1 2.1 7.9 0.2 4.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Ima1_N PF09779.4 GAM27176.1 - 9.7 6.6 22.2 9.2 6.7 3.5 3.7 2 1 1 3 3 3 0 Ima1 N-terminal domain PPR_2 PF13041.1 GAM27177.1 - 7.5e-07 29.0 0.1 0.035 14.0 0.0 5.5 5 0 0 5 5 5 1 PPR repeat family TPR_14 PF13428.1 GAM27177.1 - 0.00032 21.0 1.2 0.16 12.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM27177.1 - 0.0015 19.1 4.1 1.3 9.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR_3 PF13812.1 GAM27177.1 - 0.0036 17.4 0.6 15 6.1 0.0 5.5 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 GAM27177.1 - 0.0037 17.5 3.0 0.57 10.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 GAM27177.1 - 0.02 14.8 3.0 1.8 8.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM27177.1 - 0.023 14.5 1.2 3.9 7.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM27177.1 - 0.09 13.2 8.3 0.11 12.9 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Orthoreo_P10 PF07204.6 GAM27178.1 - 0.038 13.7 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Dicty_CAR PF05462.6 GAM27179.1 - 1.4e-161 536.4 27.3 1.9e-161 536.0 18.9 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM27179.1 - 1.1e-11 44.2 24.5 1.1e-11 44.2 17.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.12 GAM27179.1 - 1e-06 27.7 14.2 2e-06 26.8 9.9 1.4 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Peroxin-13_N PF04088.8 GAM27179.1 - 0.0077 16.2 0.2 2.3 8.1 0.2 2.7 2 1 0 2 2 2 2 Peroxin 13, N-terminal region Git3_C PF11970.3 GAM27179.1 - 0.63 9.8 6.2 0.36 10.6 1.8 2.6 2 1 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term FA_desaturase PF00487.19 GAM27180.1 - 1.8e-40 139.0 14.4 2.5e-40 138.5 10.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAM27180.1 - 3.1e-25 87.7 0.0 6.7e-25 86.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nol1_Nop2_Fmu PF01189.12 GAM27181.1 - 1.2e-34 119.9 0.0 2.7e-34 118.8 0.0 1.5 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 GAM27181.1 - 2.3e-10 40.2 0.0 4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM27181.1 - 5.5e-07 29.7 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 GAM27181.1 - 2.5e-06 27.4 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM27181.1 - 1e-05 26.0 0.0 1.9e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.15 GAM27181.1 - 3.5e-05 23.4 0.1 7.6e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 PUA domain PCMT PF01135.14 GAM27181.1 - 0.045 13.2 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 GAM27181.1 - 0.047 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 ATP-synt_J PF04911.7 GAM27181.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 ATP synthase j chain DSHCT PF08148.7 GAM27183.1 - 7.5e-55 184.9 0.2 1.7e-54 183.8 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 GAM27183.1 - 1.6e-20 73.4 5.1 4.1e-19 68.7 3.5 2.3 1 1 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.24 GAM27183.1 - 2.1e-20 72.9 0.0 5.8e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM27183.1 - 2.2e-05 24.1 0.0 0.00011 21.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cytochrome-c551 PF10643.4 GAM27183.1 - 0.015 14.5 0.6 0.082 12.1 0.5 2.0 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 SDA1 PF05285.7 GAM27183.1 - 0.91 8.7 9.8 1.5 8.0 6.8 1.2 1 0 0 1 1 1 0 SDA1 Prog_receptor PF02161.10 GAM27183.1 - 2.5 6.8 8.4 4 6.1 5.8 1.2 1 0 0 1 1 1 0 Progesterone receptor Nop14 PF04147.7 GAM27183.1 - 6.2 4.6 18.1 3 5.6 10.3 1.9 2 0 0 2 2 2 0 Nop14-like family MOZ_SAS PF01853.13 GAM27184.1 - 1.2e-92 308.3 0.5 2.8e-92 307.1 0.4 1.6 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 GAM27184.1 - 6.1e-20 70.6 2.9 1.3e-19 69.6 2.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain He_PIG_assoc PF10632.4 GAM27184.1 - 0.089 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase RRM_1 PF00076.17 GAM27185.1 - 7e-17 60.8 0.0 9.6e-17 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27185.1 - 9.3e-15 54.3 0.0 1.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27185.1 - 4.1e-08 32.9 0.0 6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 GAM27185.1 - 0.029 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 GAM27185.1 - 0.03 14.0 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.1 GAM27185.1 - 0.076 12.7 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 GAM27186.1 - 3.4e-49 167.3 0.8 5.1e-35 120.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27186.1 - 7.6e-30 103.8 0.0 4.3e-29 101.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_7 PF13508.1 GAM27186.1 - 3.1e-06 27.2 0.0 7.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM27186.1 - 0.00023 21.0 0.0 0.00066 19.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 GAM27186.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_6 PF13516.1 GAM27187.1 - 1.2e-28 95.8 53.9 0.04 13.9 0.0 17.3 16 1 0 17 17 17 11 Leucine Rich repeat LRR_4 PF12799.2 GAM27187.1 - 1.8e-15 56.1 46.9 0.1 12.2 0.0 11.3 4 2 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM27187.1 - 2.9e-09 35.6 38.2 13 6.3 0.9 14.8 14 3 2 16 16 16 5 Leucine Rich Repeat LRR_8 PF13855.1 GAM27187.1 - 0.0003 20.4 46.7 0.2 11.4 1.8 9.3 6 3 1 8 8 8 5 Leucine rich repeat LRR_7 PF13504.1 GAM27187.1 - 0.0073 16.3 40.7 11 6.7 0.0 14.3 18 0 0 18 18 18 2 Leucine rich repeat MM_CoA_mutase PF01642.17 GAM27188.1 - 2e-243 808.2 0.6 2.4e-243 807.9 0.4 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 GAM27188.1 - 2.7e-12 46.6 0.2 5.4e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 B12 binding domain PhnI PF05861.7 GAM27188.1 - 0.035 12.6 0.0 0.067 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Pkinase PF00069.20 GAM27189.1 - 7.2e-74 248.2 0.0 1.8e-73 246.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27189.1 - 5e-37 127.3 0.0 9e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27189.1 - 1.6e-06 27.2 0.0 2.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM27189.1 - 0.035 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 GAM27189.1 - 0.11 11.7 0.1 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RVT_1 PF00078.22 GAM27191.1 - 2.7e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FNIP PF05725.7 GAM27192.1 - 1.2e-48 162.7 27.9 1.4e-11 44.1 0.3 7.6 3 3 2 8 8 8 8 FNIP Repeat DUF605 PF04652.11 GAM27193.1 - 0.53 9.6 31.7 0.9 8.8 22.0 1.3 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 GAM27193.1 - 1.5 8.6 17.5 1.8 8.3 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM196 PF15265.1 GAM27193.1 - 2.4 7.3 20.0 2.5 7.2 13.8 1.1 1 0 0 1 1 1 0 FAM196 family Mitofilin PF09731.4 GAM27193.1 - 5.7 5.4 6.8 6.2 5.3 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Fork_head PF00250.13 GAM27194.1 - 0.00048 20.1 0.0 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 Fork head domain Oxysterol_BP PF01237.13 GAM27195.1 - 1.7e-57 194.5 0.0 2.5e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein E1-E2_ATPase PF00122.15 GAM27196.1 - 3.7e-22 78.4 0.0 1.2e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM27196.1 - 8.5e-19 68.8 0.2 5.8e-15 56.2 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 GAM27196.1 - 4.5e-16 59.5 0.1 4e-15 56.5 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM27196.1 - 5.6e-11 42.2 0.0 1.8e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 GAM27196.1 - 0.0001 21.9 0.0 0.017 14.6 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pentapeptide_4 PF13599.1 GAM27197.1 - 7.7e-33 112.1 45.0 1.1e-13 50.7 5.5 3.4 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 GAM27197.1 - 6.4e-25 85.9 13.1 4.5e-08 32.1 0.4 4.4 2 1 0 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 GAM27197.1 - 2.5e-16 59.2 26.2 6.5e-08 32.3 1.4 4.9 2 1 3 5 5 5 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 GAM27197.1 - 1.6e-07 31.4 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain FNIP PF05725.7 GAM27198.1 - 3.7e-96 314.8 63.1 5.6e-15 55.0 1.3 9.1 3 2 11 14 14 14 12 FNIP Repeat LRR_7 PF13504.1 GAM27198.1 - 0.53 10.7 8.3 2.2e+02 2.7 0.0 7.0 7 0 0 7 7 7 0 Leucine rich repeat MMR_HSR1 PF01926.18 GAM27199.1 - 1.7e-15 57.0 0.5 5.2e-13 48.9 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM27199.1 - 2e-06 27.1 0.9 5.9e-05 22.3 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM27199.1 - 0.0069 15.5 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 GAM27199.1 - 0.012 16.1 1.5 0.22 11.9 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein cobW PF02492.14 GAM27199.1 - 0.025 14.0 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IceA2 PF05862.6 GAM27199.1 - 0.15 11.7 0.8 0.42 10.3 0.6 1.7 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Mito_carr PF00153.22 GAM27200.1 - 6e-51 170.1 5.8 1.5e-18 66.2 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RrnaAD PF00398.15 GAM27201.1 - 1.1e-49 168.8 0.0 1.6e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 GAM27201.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM27201.1 - 0.0033 17.9 0.0 0.0076 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM27201.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 GAM27201.1 - 0.17 11.6 0.2 0.85 9.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain VWA_3 PF13768.1 GAM27202.1 - 4.8e-29 101.0 0.0 1.1e-28 99.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 GAM27202.1 - 8.4e-21 73.8 0.3 1.8e-20 72.8 0.2 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 GAM27202.1 - 5.5e-13 49.3 0.1 3.3e-12 46.8 0.0 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.23 GAM27202.1 - 6.6e-12 45.5 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 GAM27202.1 - 2.3e-06 26.9 0.0 4.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 GAM27202.1 - 3.9e-05 23.5 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF221 PF02714.10 GAM27203.1 - 3.7e-84 282.3 17.9 7.8e-84 281.3 12.4 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 GAM27203.1 - 8.7e-31 106.6 4.2 8.7e-31 106.6 2.9 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 GAM27203.1 - 0.0029 18.0 0.3 0.0065 16.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DX PF01666.12 GAM27204.1 - 0.5 10.8 3.6 0.89 10.0 0.1 2.8 3 0 0 3 3 3 0 DX module Nodulin_late PF07127.6 GAM27204.1 - 5.8 7.1 8.6 31 4.7 1.1 3.2 2 0 0 2 2 2 0 Late nodulin protein Amidohydro_1 PF01979.15 GAM27205.1 - 3.8e-42 145.1 3.5 5.6e-42 144.5 2.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family NOG1 PF06858.9 GAM27205.1 - 4.1e-27 93.8 0.9 1.1e-26 92.4 0.6 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 GAM27205.1 - 2.3e-18 66.2 0.1 9.1e-18 64.3 0.0 2.2 2 0 0 2 2 1 1 50S ribosome-binding GTPase NOGCT PF08155.6 GAM27205.1 - 6.5e-15 54.5 3.2 2.4e-14 52.7 2.2 2.1 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.13 GAM27205.1 - 7.9e-12 44.7 0.0 1.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Amidohydro_4 PF13147.1 GAM27205.1 - 4.4e-10 40.0 0.4 1.9e-09 37.9 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM27205.1 - 4.2e-07 29.5 0.4 7.3e-06 25.4 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase family Miro PF08477.8 GAM27205.1 - 2.9e-05 24.5 0.0 0.00024 21.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Amidohydro_5 PF13594.1 GAM27205.1 - 0.00016 21.4 0.5 0.00038 20.2 0.0 2.0 2 0 0 2 2 1 1 Amidohydrolase GTP_EFTU PF00009.22 GAM27205.1 - 0.0014 18.1 0.0 0.018 14.5 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 GAM27205.1 - 0.0014 17.7 0.2 0.019 14.0 0.0 2.7 3 0 0 3 3 3 1 AIG1 family DUF258 PF03193.11 GAM27205.1 - 0.012 14.8 0.0 0.035 13.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 ArgK PF03308.11 GAM27205.1 - 0.014 14.1 0.0 4.2 6.0 0.0 2.4 2 0 0 2 2 2 0 ArgK protein SRPRB PF09439.5 GAM27205.1 - 0.021 14.0 0.0 0.056 12.6 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4129 PF13559.1 GAM27205.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Corona_nucleoca PF00937.13 GAM27205.1 - 0.22 10.4 3.4 0.36 9.7 2.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Dynamin_N PF00350.18 GAM27205.1 - 0.27 11.0 2.3 2.9 7.6 0.0 2.9 2 1 1 3 3 3 0 Dynamin family Transformer PF06495.6 GAM27205.1 - 0.37 10.6 8.4 0.69 9.7 5.8 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein AAA_17 PF13207.1 GAM27205.1 - 0.42 11.4 3.8 3 8.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain DUF1227 PF06777.6 GAM27206.1 - 4.3e-53 178.9 0.3 1e-52 177.7 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 GAM27206.1 - 3.7e-50 169.7 0.3 7e-50 168.8 0.2 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 GAM27206.1 - 4.2e-47 160.2 0.1 1e-46 158.9 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 GAM27206.1 - 3.1e-05 22.9 0.1 0.00033 19.5 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM27206.1 - 0.02 14.7 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Thioredoxin PF00085.15 GAM27207.1 - 8.8e-51 169.9 0.0 6e-29 99.7 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 GAM27207.1 - 1e-12 48.2 3.9 2.2e-05 24.6 0.3 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 GAM27207.1 - 5.9e-10 39.1 1.2 0.0012 18.9 0.0 3.2 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 GAM27207.1 - 1.2e-07 31.4 0.3 0.00035 20.2 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.1 GAM27207.1 - 1.4e-07 31.4 0.0 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 GAM27207.1 - 3.9e-06 26.4 0.4 0.0051 16.3 0.0 2.5 2 1 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 GAM27207.1 - 1.1e-05 25.1 0.1 0.073 12.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_6 PF13848.1 GAM27207.1 - 3.3e-05 23.7 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.1 GAM27207.1 - 0.00012 21.6 0.1 0.23 11.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.1 GAM27207.1 - 0.00058 19.4 0.1 0.3 10.5 0.0 2.6 3 0 0 3 3 3 2 F plasmid transfer operon protein EpuA PF11772.3 GAM27207.1 - 0.022 14.1 3.5 0.052 12.9 2.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta zf-FCS PF06467.9 GAM27207.1 - 0.036 13.6 1.1 2 8.1 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DDE_Tnp_1_2 PF13586.1 GAM27207.1 - 0.082 13.1 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Transposase DDE domain Hpt PF01627.18 GAM27208.1 - 1.2e-11 44.4 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain PPR PF01535.15 GAM27208.1 - 0.00045 20.0 0.5 0.00097 18.9 0.3 1.6 1 0 0 1 1 1 1 PPR repeat PPR_1 PF12854.2 GAM27208.1 - 0.0022 17.4 0.1 0.0051 16.2 0.1 1.7 1 0 0 1 1 1 1 PPR repeat PPR_2 PF13041.1 GAM27208.1 - 0.0089 15.9 1.1 0.032 14.2 0.1 2.1 2 0 0 2 2 2 1 PPR repeat family RA PF00788.18 GAM27209.1 - 0.0029 18.0 0.0 0.0074 16.7 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Tir_receptor_C PF07489.6 GAM27210.1 - 0.42 10.3 7.3 0.98 9.1 5.0 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Metallophos_C PF14008.1 GAM27211.1 - 2.8e-16 59.3 0.1 5.7e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 GAM27211.1 - 9.2e-14 51.3 3.3 1.4e-13 50.7 2.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 GAM27211.1 - 3.7e-08 32.3 0.3 1.6e-07 30.2 0.1 1.8 1 1 1 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 GAM27211.1 - 3.5e-06 26.9 0.1 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PseudoU_synth_1 PF01416.15 GAM27212.1 - 1.2e-30 105.9 0.0 2.3e-19 69.7 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase U-box PF04564.10 GAM27214.1 - 1.7e-08 34.2 0.1 8.9e-08 31.9 0.0 2.2 1 1 0 1 1 1 1 U-box domain zf-Nse PF11789.3 GAM27214.1 - 0.011 15.2 0.3 0.038 13.5 0.1 2.0 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit EthD PF07110.6 GAM27214.1 - 0.018 15.9 0.3 1.6 9.7 0.0 2.7 1 1 1 2 2 2 0 EthD domain zf-RING_UBOX PF13445.1 GAM27214.1 - 0.023 14.3 0.2 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 GAM27214.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 GAM27214.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1772 PF08592.6 GAM27215.1 - 9.9e-08 31.8 3.6 1e-07 31.7 0.9 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) UPF0020 PF01170.13 GAM27216.1 - 8.9e-11 41.6 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 GAM27216.1 - 1.4e-10 41.2 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 GAM27216.1 - 1.4e-05 24.7 2.3 0.00061 19.3 0.0 3.2 3 1 0 3 3 3 1 DNA methylase AhpC-TSA_2 PF13911.1 GAM27217.1 - 8.5e-18 64.3 0.0 1.8e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 GAM27217.1 - 1.8e-05 24.3 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 GAM27217.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin FAE1_CUT1_RppA PF08392.7 GAM27218.1 - 2.5e-125 417.3 0.0 3.4e-125 416.9 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 GAM27218.1 - 8e-11 41.8 0.0 5.1e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.10 GAM27218.1 - 3.2e-10 40.1 0.0 5.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 GAM27218.1 - 0.0082 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 GAM27218.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 GAM27218.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain GST_C PF00043.20 GAM27219.1 - 1.2e-11 44.4 0.0 2.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM27219.1 - 4.3e-11 42.8 0.0 8.4e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM27219.1 - 1.3e-10 41.2 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM27219.1 - 5.1e-10 39.2 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM27219.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM27219.1 - 9.9e-07 29.1 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM27220.1 - 1.4e-08 34.7 0.0 3.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM27220.1 - 3.4e-08 33.3 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM27220.1 - 4.6e-06 26.4 0.1 2.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM27220.1 - 0.00032 21.1 0.0 0.00047 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3683 PF12447.3 GAM27220.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) Malate_synthase PF01274.17 GAM27221.1 - 3.4e-97 325.6 0.0 1.2e-96 323.8 0.0 1.7 1 1 0 1 1 1 1 Malate synthase DUF4366 PF14283.1 GAM27221.1 - 0.14 11.5 0.1 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PIGA PF08288.7 GAM27222.1 - 6.2e-44 148.2 1.3 1.1e-43 147.5 0.3 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 GAM27222.1 - 4.4e-29 101.1 0.0 6.8e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 GAM27222.1 - 9.7e-16 57.9 0.1 1.5e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 GAM27222.1 - 5e-12 46.1 0.0 9.1e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM27222.1 - 7.2e-09 35.9 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 GAM27222.1 - 7.8e-05 22.5 0.2 0.00014 21.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 GAM27222.1 - 0.0028 17.8 0.1 0.0071 16.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 eIF-5a PF01287.15 GAM27223.1 - 2.9e-23 81.5 0.2 4e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 GAM27223.1 - 0.094 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain PLDc_2 PF13091.1 GAM27224.1 - 8.3e-08 32.0 0.0 0.00052 19.7 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM27224.1 - 1.1e-06 28.2 0.3 0.0014 18.3 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif SelP_N PF04592.9 GAM27224.1 - 0.0064 15.9 8.2 0.017 14.4 5.7 1.7 1 0 0 1 1 1 1 Selenoprotein P, N terminal region DUF1725 PF08333.6 GAM27224.1 - 0.17 11.2 0.1 0.42 9.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) BRF1 PF07741.8 GAM27224.1 - 0.98 9.6 4.2 2.2 8.5 2.9 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Zip PF02535.17 GAM27224.1 - 1.3 8.0 9.4 2.1 7.2 6.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 GAM27224.1 - 4.4 6.0 24.0 7.3 5.3 16.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FNIP PF05725.7 GAM27225.1 - 1.4e-35 120.9 11.0 8.8e-10 38.3 0.0 5.7 4 2 1 5 5 5 5 FNIP Repeat E1-E2_ATPase PF00122.15 GAM27227.1 - 2e-19 69.5 0.0 5e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 GAM27227.1 - 4.2e-16 59.6 0.0 1.1e-15 58.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM27227.1 - 4.1e-12 45.9 0.0 1.5e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 GAM27227.1 - 7.3e-12 46.1 0.3 8.8e-08 32.8 0.3 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM27227.1 - 0.007 15.9 0.2 0.024 14.2 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase KAR9 PF08580.5 GAM27227.1 - 0.72 8.0 3.2 1.1 7.4 2.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TIG PF01833.19 GAM27228.1 - 6.1e-16 58.1 92.8 1.4e-07 31.4 2.1 11.4 10 2 2 12 12 12 8 IPT/TIG domain EGF_2 PF07974.8 GAM27228.1 - 0.09 12.9 14.1 0.034 14.3 7.8 1.8 2 0 0 2 2 2 0 EGF-like domain Pentapeptide_4 PF13599.1 GAM27229.1 - 4.7e-18 64.7 43.8 1.5e-09 37.5 10.8 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 GAM27229.1 - 1.1e-10 41.2 36.5 1.7e-05 24.5 6.2 3.5 3 0 0 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 GAM27229.1 - 4.8e-07 28.8 2.9 0.032 13.4 0.2 3.5 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) BAF1_ABF1 PF04684.8 GAM27229.1 - 6.3 5.5 11.4 11 4.7 7.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Prefoldin PF02996.12 GAM27230.1 - 3.5e-18 65.3 0.2 3.5e-18 65.3 0.2 2.9 2 1 1 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.1 GAM27230.1 - 2.4e-08 33.6 0.1 2.4e-08 33.6 0.1 3.6 2 1 2 4 4 4 1 Prefoldin subunit Myosin_head PF00063.16 GAM27231.1 - 1.5e-213 710.7 6.9 1.5e-213 710.7 4.8 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 GAM27231.1 - 6.3e-28 96.7 3.5 1.2e-27 95.7 0.9 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 GAM27231.1 - 1.6e-08 33.4 15.5 0.0005 19.4 0.8 5.5 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_16 PF13191.1 GAM27231.1 - 0.017 15.1 0.9 0.17 11.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain ERM PF00769.14 GAM27231.1 - 0.1 12.1 33.2 0.064 12.7 13.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Myosin_N PF02736.14 GAM27232.1 - 3.3e-08 33.0 0.5 4e-08 32.8 0.3 1.1 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain FNIP PF05725.7 GAM27233.1 - 9.4e-68 223.9 5.4 2.4e-13 49.7 0.0 9.8 5 4 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 GAM27233.1 - 1.6e-07 31.1 7.7 7.5 6.5 0.1 7.6 5 4 3 8 8 8 4 Protein of unknown function (DUF1769) E1-E2_ATPase PF00122.15 GAM27234.1 - 1.7e-60 203.9 0.2 3.3e-60 202.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 GAM27234.1 - 5.1e-43 146.7 7.9 1.3e-42 145.4 1.6 2.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 GAM27234.1 - 1.6e-26 94.0 0.0 5.1e-26 92.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM27234.1 - 2.7e-17 62.5 0.0 4.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM27234.1 - 1.2e-12 48.3 0.0 3.4e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM27234.1 - 3.1e-12 45.7 0.0 7.1e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM27234.1 - 9.6e-05 22.0 0.1 0.0055 16.3 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LRR_7 PF13504.1 GAM27235.1 - 0.0094 15.9 1.4 2.4 8.7 0.1 3.6 2 0 0 2 2 2 1 Leucine rich repeat F-box-like PF12937.2 GAM27235.1 - 0.02 14.6 0.9 0.048 13.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like DUF4649 PF15507.1 GAM27235.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) LRR_4 PF12799.2 GAM27235.1 - 0.2 11.2 14.6 0.05 13.2 2.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM27235.1 - 0.38 10.9 19.5 2.1 8.6 0.1 4.8 4 1 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 GAM27235.1 - 1.2 9.4 15.8 0.96 9.7 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat DUF3184 PF11380.3 GAM27236.1 - 2.1e-09 35.9 3.8 0.016 13.1 0.0 4.0 1 1 2 4 4 4 4 Protein of unknown function (DUF3184) Oxysterol_BP PF01237.13 GAM27237.1 - 2.8e-106 354.9 1.7 3.3e-106 354.7 1.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein RasGEF PF00617.14 GAM27238.1 - 2.1e-56 190.6 2.0 9.7e-56 188.4 0.1 2.3 2 0 0 2 2 2 1 RasGEF domain LRR_4 PF12799.2 GAM27238.1 - 2.1e-42 142.0 40.1 1.1e-09 37.6 0.2 8.6 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27238.1 - 4.6e-32 109.5 36.3 4.7e-10 39.0 3.5 6.1 3 2 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 GAM27238.1 - 1.6e-20 69.9 35.6 0.06 13.4 0.2 13.1 12 0 0 12 12 12 8 Leucine Rich Repeat RasGEF_N PF00618.15 GAM27238.1 - 3.8e-18 65.4 1.0 2.5e-17 62.8 0.1 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif LRR_7 PF13504.1 GAM27238.1 - 1.9e-13 48.1 39.4 0.26 11.6 0.0 11.9 12 0 0 12 12 12 5 Leucine rich repeat LRR_5 PF13306.1 GAM27238.1 - 0.0011 18.6 0.2 0.17 11.5 0.0 3.6 2 1 2 4 4 4 1 Leucine rich repeats (6 copies) LRR_3 PF07725.7 GAM27238.1 - 0.33 10.8 4.9 18 5.3 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 GAM27238.1 - 0.61 10.3 34.5 7.2 7.0 0.0 10.0 11 1 1 12 12 12 0 Leucine Rich repeat IQ PF00612.22 GAM27238.1 - 1 9.1 16.2 0.49 10.1 2.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF3361 PF11841.3 GAM27239.1 - 0.0041 16.8 2.3 0.0061 16.2 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) WAPL PF07814.8 GAM27239.1 - 0.0051 15.5 9.2 0.11 11.1 1.4 2.1 1 1 1 2 2 2 2 Wings apart-like protein regulation of heterochromatin Dicty_spore_N PF04562.7 GAM27240.1 - 5.9e-44 149.1 51.4 3.4e-25 88.6 16.2 5.7 3 2 2 5 5 5 2 Dictyostelium spore coat protein, N terminus Aa_trans PF01490.13 GAM27241.1 - 5e-13 48.3 37.1 9.2e-13 47.4 25.7 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 GAM27241.1 - 5.9e-05 22.0 20.7 5.9e-05 22.0 14.3 2.5 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Ribosomal_S30 PF04758.9 GAM27242.1 - 2.6e-15 55.8 6.2 3.1e-15 55.6 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CH PF00307.26 GAM27243.1 - 3.9e-13 49.3 0.0 1.5e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain RA PF00788.18 GAM27243.1 - 2e-05 24.9 0.0 4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain BNIP3 PF06553.7 GAM27244.1 - 0.02 14.3 2.1 0.034 13.5 1.4 1.3 1 0 0 1 1 1 0 BNIP3 ApbE PF02424.10 GAM27244.1 - 0.022 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 ApbE family SR-25 PF10500.4 GAM27244.1 - 0.027 13.9 1.5 0.041 13.3 1.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.3 GAM27244.1 - 0.14 11.7 6.0 2.9 7.4 3.3 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF515 PF04415.7 GAM27244.1 - 0.21 9.7 7.2 0.32 9.1 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RhoGEF PF00621.15 GAM27245.1 - 1.8e-42 145.2 0.8 1.8e-42 145.2 0.5 2.0 2 0 0 2 2 2 1 RhoGEF domain DZR PF12773.2 GAM27245.1 - 9.7e-05 22.1 1.1 0.00022 20.9 0.7 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM27245.1 - 0.00024 20.1 4.3 0.00052 19.1 3.0 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM27245.1 - 0.00065 19.1 4.6 0.0013 18.1 3.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain NOB1_Zn_bind PF08772.6 GAM27245.1 - 0.071 12.9 0.5 0.22 11.3 0.3 1.9 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Ycf1 PF05758.7 GAM27245.1 - 0.075 10.7 6.7 0.13 9.9 4.6 1.4 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 GAM27245.1 - 0.081 11.0 2.3 0.13 10.4 1.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 D5_N PF08706.6 GAM27245.1 - 0.84 9.7 4.8 1.9 8.5 3.4 1.5 1 0 0 1 1 1 0 D5 N terminal like zf-RanBP PF00641.13 GAM27245.1 - 1.5 7.9 9.8 3 7.0 6.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Synaptobrevin PF00957.16 GAM27246.1 - 2.8e-30 103.7 2.5 4.2e-30 103.1 1.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAM27246.1 - 4.1e-26 90.3 0.2 1.1e-25 88.9 0.1 1.8 2 1 0 2 2 2 1 Regulated-SNARE-like domain DUF2393 PF09624.5 GAM27246.1 - 0.017 14.6 1.3 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) DUF3753 PF12575.3 GAM27246.1 - 0.11 12.3 1.8 0.26 11.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) SRP-alpha_N PF04086.8 GAM27246.1 - 0.18 11.1 2.5 0.27 10.5 1.7 1.4 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1212 PF06738.7 GAM27247.1 - 0.94 8.9 3.3 1.1 8.6 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Mpv17_PMP22 PF04117.7 GAM27248.1 - 1.1e-06 28.2 0.3 2.4e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Mpv17 / PMP22 family Lactamase_B_2 PF12706.2 GAM27249.1 - 3.1e-35 121.4 0.1 7.8e-33 113.6 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 GAM27249.1 - 3.8e-10 39.0 0.2 8.7e-10 37.9 0.1 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 GAM27249.1 - 1.3e-08 34.7 0.0 4.6e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Dicty_REP PF05086.7 GAM27249.1 - 0.016 13.0 14.0 0.024 12.4 9.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 GAM27249.1 - 0.15 11.8 19.3 0.31 10.8 13.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.8 GAM27249.1 - 2.5 6.1 6.8 3.7 5.5 4.7 1.2 1 0 0 1 1 1 0 Menin FH2 PF02181.18 GAM27250.1 - 1.1e-56 192.3 8.0 3.6e-56 190.6 0.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain Tox-GHH PF15636.1 GAM27250.1 - 0.016 14.7 3.3 0.041 13.5 2.3 1.7 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Med11 PF10280.4 GAM27250.1 - 0.025 14.6 8.1 0.025 14.5 1.2 2.9 2 0 0 2 2 2 0 Mediator complex protein Mito_carr PF00153.22 GAM27251.1 - 7.3e-75 246.7 1.1 9.1e-24 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 GAM27251.1 - 0.009 15.9 0.0 9.5 6.2 0.0 3.2 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF3938 PF13074.1 GAM27251.1 - 0.074 12.9 0.1 0.86 9.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) tRNA-synt_1e PF01406.14 GAM27252.1 - 1.8e-103 345.8 0.7 3.1e-103 345.0 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 GAM27252.1 - 1.4e-09 37.1 6.7 4.5e-05 22.3 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 GAM27252.1 - 0.0023 18.1 0.0 0.0068 16.6 0.0 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1 PF00133.17 GAM27252.1 - 0.0054 14.7 0.0 0.018 13.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) K_channel_TID PF07941.6 GAM27252.1 - 0.011 15.9 5.1 0.025 14.7 3.6 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain tRNA-synt_1f PF01921.13 GAM27252.1 - 0.028 13.0 0.1 0.34 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) ABC_tran PF00005.22 GAM27253.1 - 1.3e-28 100.0 0.1 2.4e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 GAM27253.1 - 2.3e-14 53.2 31.6 5.1e-14 52.0 21.9 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 GAM27253.1 - 1e-09 38.8 0.0 1e-09 38.8 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 GAM27253.1 - 0.0014 17.8 0.2 0.0027 16.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 GAM27253.1 - 0.003 16.4 0.2 0.0051 15.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 GAM27253.1 - 0.025 14.1 0.3 0.065 12.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM27253.1 - 0.03 14.6 0.1 0.03 14.6 0.1 2.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 GAM27253.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 GAM27253.1 - 0.084 13.0 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 GAM27253.1 - 0.11 11.6 0.5 12 5.0 0.1 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.2 GAM27253.1 - 4.8 5.9 26.0 12 4.6 18.0 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.22 GAM27254.1 - 8.8e-28 97.3 0.0 1.6e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 GAM27254.1 - 2.2e-17 63.9 2.5 2.9e-16 60.3 1.7 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 GAM27254.1 - 1.2e-16 60.7 39.1 2.8e-16 59.4 27.1 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_15 PF13175.1 GAM27254.1 - 2.1e-05 23.7 0.2 0.0026 16.8 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 GAM27254.1 - 0.00065 18.9 0.7 0.05 12.8 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.10 GAM27254.1 - 0.0026 16.4 0.0 0.0044 15.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 GAM27254.1 - 0.055 11.9 0.2 7 4.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 GAM27254.1 - 0.064 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 GAM27254.1 - 0.37 11.0 3.6 0.32 11.3 1.0 1.9 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 GAM27254.1 - 1.7 8.0 3.3 10 5.4 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein FNIP PF05725.7 GAM27256.1 - 1.8e-61 203.8 31.0 1.6e-13 50.3 0.4 11.9 7 2 6 14 14 14 12 FNIP Repeat DUF1769 PF08588.5 GAM27256.1 - 8.9e-07 28.7 0.7 7.5 6.5 0.0 6.1 3 2 2 5 5 5 4 Protein of unknown function (DUF1769) PHD PF00628.24 GAM27257.1 - 4.2e-13 48.7 24.1 7.7e-09 35.1 6.1 2.5 2 0 0 2 2 2 2 PHD-finger FHA PF00498.21 GAM27257.1 - 6.1e-07 29.4 0.1 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-HC5HC2H PF13771.1 GAM27257.1 - 1.2e-05 25.4 9.9 0.0021 18.1 0.6 2.9 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.1 GAM27257.1 - 0.003 16.8 2.3 0.003 16.8 1.6 2.6 3 0 0 3 3 3 1 PHD-finger CAF-1_p150 PF11600.3 GAM27257.1 - 0.0046 16.3 36.1 0.0046 16.3 25.0 7.5 4 2 2 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal MFS_1 PF07690.11 GAM27258.1 - 7.2e-32 110.4 27.3 2.7e-25 88.8 4.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM27258.1 - 2.9e-11 42.6 5.7 2.9e-11 42.6 4.0 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter GRP PF07172.6 GAM27258.1 - 0.023 15.1 10.4 2.4 8.7 4.0 3.5 3 0 0 3 3 3 0 Glycine rich protein family DUF3366 PF11846.3 GAM27258.1 - 0.35 10.7 1.5 17 5.1 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Peptidase_M41 PF01434.13 GAM27259.1 - 1.7e-72 243.3 0.1 6.9e-72 241.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 GAM27259.1 - 1.5e-43 148.1 0.0 4.7e-43 146.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM27259.1 - 0.00025 21.8 1.1 0.0016 19.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 GAM27259.1 - 0.00031 20.5 0.0 0.0019 17.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.10 GAM27259.1 - 0.0013 18.8 4.1 0.075 13.2 0.0 4.0 4 0 0 4 4 4 1 FtsH Extracellular AAA_22 PF13401.1 GAM27259.1 - 0.0036 17.4 0.0 0.16 12.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 GAM27259.1 - 0.0047 17.2 2.2 0.66 10.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 GAM27259.1 - 0.0071 15.1 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 GAM27259.1 - 0.0084 16.0 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM27259.1 - 0.0088 15.9 0.2 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 GAM27259.1 - 0.01 15.2 1.6 0.11 11.9 0.4 2.6 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 GAM27259.1 - 0.013 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 GAM27259.1 - 0.019 14.6 1.1 0.064 13.0 0.8 1.9 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 GAM27259.1 - 0.021 13.9 0.0 0.042 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM27259.1 - 0.029 14.3 0.6 0.18 11.8 0.1 2.4 2 1 1 3 3 2 0 AAA ATPase domain AAA_2 PF07724.9 GAM27259.1 - 0.048 13.5 2.3 0.059 13.2 0.0 2.3 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) CDC45 PF02724.9 GAM27259.1 - 0.053 11.5 4.0 0.073 11.1 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein IstB_IS21 PF01695.12 GAM27259.1 - 0.059 12.7 1.8 0.067 12.5 0.4 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM27259.1 - 0.084 12.0 0.2 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI YtxH PF12732.2 GAM27259.1 - 0.13 12.6 2.6 0.2 12.0 0.2 2.5 2 0 0 2 2 2 0 YtxH-like protein FAM176 PF14851.1 GAM27259.1 - 2.4 7.8 5.9 4.4 6.9 4.1 1.4 1 0 0 1 1 1 0 FAM176 family AAA_21 PF13304.1 GAM27259.1 - 2.5 7.9 8.6 0.67 9.8 1.2 2.7 3 0 0 3 3 3 0 AAA domain Oxysterol_BP PF01237.13 GAM27260.1 - 1.1e-57 195.1 0.1 1.5e-57 194.7 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Nucleoporin2 PF04096.9 GAM27260.1 - 0.29 10.9 2.4 0.56 10.0 0.1 2.1 1 1 0 2 2 2 0 Nucleoporin autopeptidase Pkinase PF00069.20 GAM27261.1 - 1.2e-64 217.9 0.0 1.2e-64 217.9 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27261.1 - 2.2e-24 85.9 0.0 2.2e-24 85.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PAT1 PF09770.4 GAM27261.1 - 0.36 9.0 45.3 0.46 8.6 31.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 GAM27261.1 - 1.2 7.2 53.7 1.6 6.8 37.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 GAM27261.1 - 1.2 8.9 26.9 1.7 8.4 18.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DLH PF01738.13 GAM27262.1 - 3.8e-38 130.9 0.0 4.3e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 GAM27262.1 - 1.1e-06 28.0 0.2 0.0023 17.2 0.0 2.3 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM27262.1 - 8.1e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM27262.1 - 0.00066 19.6 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 GAM27262.1 - 0.011 14.6 0.2 0.028 13.3 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2048) Esterase PF00756.15 GAM27262.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 GAM27262.1 - 0.028 13.2 0.0 0.53 9.1 0.0 2.2 2 1 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 GAM27262.1 - 0.034 13.7 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 GAM27262.1 - 0.053 12.7 0.1 0.13 11.5 0.0 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase AAA PF00004.24 GAM27263.1 - 5.4e-50 169.0 0.0 3.6e-37 127.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 GAM27263.1 - 2.2e-09 38.1 0.0 0.0019 19.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 GAM27263.1 - 1.2e-08 34.7 0.1 9.4e-05 22.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAM27263.1 - 3.1e-08 33.9 0.1 0.00019 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 GAM27263.1 - 8.2e-08 32.4 1.1 0.0018 18.3 0.1 4.0 2 2 0 2 2 2 1 AAA domain AAA_2 PF07724.9 GAM27263.1 - 1.9e-07 31.1 0.1 1.4e-05 25.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 GAM27263.1 - 2.6e-07 30.6 0.0 0.043 13.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 GAM27263.1 - 3.7e-07 30.0 0.1 0.073 12.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 GAM27263.1 - 1.1e-06 27.8 0.1 0.006 15.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 GAM27263.1 - 2.4e-06 27.6 0.1 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 GAM27263.1 - 2.1e-05 24.6 0.0 0.095 12.8 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Sigma54_activat PF00158.21 GAM27263.1 - 2.9e-05 23.6 0.0 0.29 10.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 GAM27263.1 - 2.9e-05 24.3 0.2 0.048 13.9 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RuvB_N PF05496.7 GAM27263.1 - 4.8e-05 22.5 0.0 0.0077 15.3 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 GAM27263.1 - 5.5e-05 22.4 1.2 0.0021 17.2 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 GAM27263.1 - 7.6e-05 21.5 0.0 0.007 15.1 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus NACHT PF05729.7 GAM27263.1 - 0.00031 20.4 2.4 1.4 8.5 0.0 3.6 4 0 0 4 4 4 1 NACHT domain AAA_24 PF13479.1 GAM27263.1 - 0.00035 20.2 0.2 0.96 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 GAM27263.1 - 0.00036 20.5 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain CDC48_2 PF02933.12 GAM27263.1 - 0.00036 20.0 0.2 0.0013 18.2 0.0 2.0 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.12 GAM27263.1 - 0.00044 19.7 0.0 0.081 12.3 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 GAM27263.1 - 0.0007 19.6 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 GAM27263.1 - 0.0014 18.2 0.0 0.3 10.7 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 GAM27263.1 - 0.0017 17.7 0.4 0.25 10.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 GAM27263.1 - 0.0019 17.3 0.3 0.028 13.5 0.0 2.6 2 1 0 2 2 2 1 KaiC AAA_19 PF13245.1 GAM27263.1 - 0.0026 17.4 0.3 0.021 14.5 0.0 2.5 3 0 0 3 3 2 1 Part of AAA domain UPF0079 PF02367.12 GAM27263.1 - 0.0031 17.1 0.1 0.98 9.0 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 GAM27263.1 - 0.0043 16.0 0.1 0.17 10.8 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 GAM27263.1 - 0.0077 16.5 0.5 0.21 11.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 GAM27263.1 - 0.012 15.1 0.0 0.13 11.7 0.0 2.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 GAM27263.1 - 0.015 15.1 0.2 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.1 GAM27263.1 - 0.018 14.5 0.8 0.87 9.1 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 GAM27263.1 - 0.022 13.6 0.0 0.95 8.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 GAM27263.1 - 0.03 14.0 0.5 21 4.7 0.0 3.4 2 2 1 3 3 3 0 Archaeal ATPase KTI12 PF08433.5 GAM27263.1 - 0.032 13.4 0.1 0.34 10.0 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 GAM27263.1 - 0.041 12.8 0.2 0.52 9.2 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 GAM27263.1 - 0.045 12.9 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein CPT PF07931.7 GAM27263.1 - 0.051 13.1 0.7 4.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein CDC48_N PF02359.13 GAM27263.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain HMG_box PF00505.14 GAM27264.1 - 2.8e-17 62.7 14.1 8.1e-14 51.6 1.9 3.6 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM27264.1 - 7.6e-11 42.2 21.6 1.7e-07 31.4 0.8 3.7 3 1 0 3 3 3 2 HMG-box domain NUT_N PF12881.2 GAM27264.1 - 0.058 12.5 1.1 0.079 12.0 0.1 1.7 2 0 0 2 2 2 0 NUT protein N terminus DUF1074 PF06382.6 GAM27264.1 - 0.11 12.4 7.8 0.16 11.8 3.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1074) Suc_Fer-like PF06999.7 GAM27265.1 - 2.9e-43 148.5 0.0 3.6e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like NPR1_like_C PF12313.3 GAM27265.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Fer2_2 PF01799.15 GAM27265.1 - 0.11 12.4 0.1 19 5.2 0.0 2.4 2 0 0 2 2 2 0 [2Fe-2S] binding domain Gly_kinase PF02595.10 GAM27266.1 - 9.3e-85 284.5 1.5 1.1e-84 284.3 1.1 1.1 1 0 0 1 1 1 1 Glycerate kinase family MPP6 PF10175.4 GAM27267.1 - 2e-07 31.3 1.4 2e-07 31.3 1.0 2.1 2 1 0 2 2 2 1 M-phase phosphoprotein 6 Neur_chan_memb PF02932.11 GAM27267.1 - 5 6.9 10.8 12 5.7 7.5 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 GAM27267.1 - 5.1 5.3 11.3 6 5.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF21 PF01595.15 GAM27268.1 - 1e-34 119.4 3.8 1.5e-34 118.8 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 GAM27268.1 - 3.2e-09 36.4 0.6 1.7e-05 24.4 0.5 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 GAM27268.1 - 1.9e-05 24.3 0.0 4.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Glyco_hydro_16 PF00722.16 GAM27269.1 - 1.3e-09 37.6 0.7 2.6e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MAM PF00629.18 GAM27269.1 - 0.0091 15.7 0.3 0.019 14.7 0.2 1.5 1 0 0 1 1 1 1 MAM domain Ribosomal_S4e PF00900.15 GAM27270.1 - 3.3e-23 81.1 0.1 5.5e-23 80.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 GAM27270.1 - 1.2e-17 63.4 6.3 2.4e-17 62.4 4.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 GAM27270.1 - 2e-10 39.9 0.1 3.5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 GAM27270.1 - 0.00011 21.7 0.1 0.00011 21.7 0.0 2.5 4 0 0 4 4 4 1 KOW motif Pkinase_Tyr PF07714.12 GAM27271.1 - 1.2e-64 217.8 0.0 1.7e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM27271.1 - 6.5e-59 199.1 0.0 1e-58 198.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 GAM27271.1 - 6e-10 38.9 10.0 6e-10 38.9 6.9 2.9 3 0 0 3 3 3 1 IPT/TIG domain SR-25 PF10500.4 GAM27271.1 - 0.0086 15.5 1.1 0.013 15.0 0.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein APH PF01636.18 GAM27271.1 - 0.018 14.7 0.2 0.037 13.7 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family ETRAMP PF09716.5 GAM27271.1 - 0.11 12.5 2.3 2.3 8.2 0.2 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fumble PF03630.9 GAM27272.1 - 5.1e-80 268.8 0.2 5.9e-80 268.6 0.2 1.0 1 0 0 1 1 1 1 Fumble Plasmodium_Vir PF05795.6 GAM27273.1 - 0.72 8.9 2.9 0.78 8.8 2.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Op_neuropeptide PF08035.6 GAM27274.1 - 0.03 13.9 0.2 0.065 12.8 0.0 1.6 2 0 0 2 2 2 0 Opioids neuropeptide Transglut_core PF01841.14 GAM27275.1 - 8.1e-12 45.3 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily BAR PF03114.13 GAM27275.1 - 0.0081 15.6 2.5 0.01 15.3 0.7 1.8 2 0 0 2 2 2 1 BAR domain DUF829 PF05705.9 GAM27276.1 - 3.5e-38 131.6 0.8 7e-38 130.6 0.5 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.8 GAM27276.1 - 0.0035 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF4509 PF14970.1 GAM27276.1 - 0.0058 16.3 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4509) Peptidase_S9 PF00326.16 GAM27276.1 - 0.049 12.8 0.5 0.13 11.4 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 GAM27276.1 - 0.11 12.2 0.0 0.41 10.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family NDK PF00334.14 GAM27277.1 - 1.8e-35 121.6 0.0 2e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Vps54 PF07928.7 GAM27278.1 - 4.8e-44 149.7 1.3 1.2e-43 148.4 0.3 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 GAM27278.1 - 1.2e-15 57.2 1.1 1.2e-15 57.2 0.8 2.3 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 GAM27278.1 - 2.3e-05 24.2 1.2 2.3e-05 24.2 0.8 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Stn1 PF10451.4 GAM27279.1 - 9.9e-05 21.3 0.2 0.00013 20.9 0.2 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 GAM27279.1 - 0.00076 19.2 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CH PF00307.26 GAM27280.1 - 3.3e-28 97.8 0.1 9.4e-16 57.8 0.0 3.4 3 0 0 3 3 3 2 Calponin homology (CH) domain RasGAP PF00616.14 GAM27280.1 - 2.2e-25 89.4 1.2 2.2e-25 89.4 0.8 3.1 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase BAR PF03114.13 GAM27281.1 - 0.007 15.8 9.3 0.09 12.2 6.4 2.1 1 1 0 1 1 1 1 BAR domain Med28 PF11594.3 GAM27281.1 - 0.074 13.2 2.4 0.29 11.3 0.3 2.6 2 1 0 2 2 2 0 Mediator complex subunit 28 Adap_comp_sub PF00928.16 GAM27282.1 - 6.2e-89 297.5 0.0 8.7e-89 297.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM27282.1 - 2.1e-10 40.4 1.7 4e-10 39.5 1.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DnaJ PF00226.26 GAM27286.1 - 5.3e-28 96.5 2.7 9.6e-28 95.7 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAM27286.1 - 4.3e-22 77.8 2.1 1.9e-18 66.1 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAM27286.1 - 1.9e-16 59.8 18.5 3.3e-16 59.0 12.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAM27286.1 - 0.0026 17.4 9.4 0.11 12.1 2.6 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 GAM27286.1 - 0.73 9.5 12.7 0.14 11.8 5.2 2.4 1 1 1 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 GAM27286.1 - 1.6 9.1 16.7 0.21 11.9 8.1 2.2 2 1 0 2 2 2 0 Cytochrome c3 BCIP PF13862.1 GAM27289.1 - 3.4e-37 127.8 1.2 3.4e-37 127.8 0.8 2.7 2 2 0 2 2 2 1 p21-C-terminal region-binding protein Cwf_Cwc_15 PF04889.7 GAM27289.1 - 0.0019 17.9 19.9 0.0019 17.9 13.8 2.3 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein SOBP PF15279.1 GAM27289.1 - 0.02 15.2 8.7 0.028 14.8 6.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein MSP1_C PF07462.6 GAM27289.1 - 0.037 12.4 19.3 0.034 12.5 9.4 2.2 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Nucleo_P87 PF07267.6 GAM27289.1 - 0.043 12.5 15.7 0.066 11.9 10.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mem_trans PF03547.13 GAM27289.1 - 0.048 11.9 1.2 0.054 11.7 0.8 1.4 1 0 0 1 1 1 0 Membrane transport protein Astro_capsid PF03115.9 GAM27289.1 - 0.057 11.6 15.5 0.088 11.0 10.7 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 GAM27289.1 - 0.077 11.4 19.9 0.13 10.7 13.8 1.3 1 0 0 1 1 1 0 Daxx Family Med3 PF11593.3 GAM27289.1 - 0.55 9.4 22.1 0.24 10.6 13.1 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ndc1_Nup PF09531.5 GAM27289.1 - 1.4 7.2 10.0 1.8 6.8 6.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RXT2_N PF08595.6 GAM27289.1 - 4 7.2 16.6 0.76 9.5 8.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Neur_chan_memb PF02932.11 GAM27289.1 - 6.2 6.6 11.4 4.1 7.2 6.3 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BTV_NS2 PF04514.7 GAM27289.1 - 7.2 5.3 17.7 1.3 7.7 9.1 1.9 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 MRP-S26 PF14943.1 GAM27290.1 - 5.7 6.4 14.4 6.6 6.2 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Myb_DNA-binding PF00249.26 GAM27291.1 - 5.3e-26 90.4 0.7 1.2e-15 57.2 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM27291.1 - 8e-21 73.9 0.8 2.4e-15 56.3 0.2 3.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF4326 PF14216.1 GAM27292.1 - 4.5e-15 55.9 0.1 6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) Arf PF00025.16 GAM27293.1 - 2.4e-55 186.4 0.0 2.9e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM27293.1 - 4e-09 35.9 0.0 6.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 GAM27293.1 - 3.4e-07 30.7 0.0 4.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM27293.1 - 3.7e-05 22.9 0.0 7.4e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM27293.1 - 4.1e-05 23.5 0.0 6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 GAM27293.1 - 5.4e-05 22.6 0.0 6.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM27293.1 - 0.00066 18.4 2.1 0.018 13.7 0.2 2.1 1 1 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.1 GAM27293.1 - 0.0082 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 GAM27293.1 - 0.031 13.9 0.4 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 GAM27293.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 GAM27293.1 - 0.13 13.1 0.2 0.19 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 GAM27293.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pro_isomerase PF00160.16 GAM27295.1 - 1.9e-47 161.3 0.1 2.3e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF PF03031.13 GAM27295.1 - 0.013 15.2 0.0 0.018 14.6 0.0 1.4 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Transglut_core PF01841.14 GAM27296.1 - 4.4e-13 49.4 0.0 9.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ferrochelatase PF00762.14 GAM27297.1 - 1.3e-104 349.5 0.0 1.6e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Dicistro_VP4 PF11492.3 GAM27297.1 - 0.073 13.0 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 ACC_epsilon PF13822.1 GAM27297.1 - 0.14 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Coprogen_oxidas PF01218.13 GAM27298.1 - 5.3e-94 314.0 0.1 8.1e-93 310.2 0.1 1.9 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase DUF2392 PF10288.4 GAM27299.1 - 2e-21 76.3 1.2 3e-21 75.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) PAPS_reduct PF01507.14 GAM27299.1 - 0.014 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Imm25 PF15571.1 GAM27299.1 - 0.03 14.4 0.2 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 25 FERM_M PF00373.13 GAM27300.1 - 2e-20 73.2 0.1 4.5e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 GAM27300.1 - 0.0038 17.2 0.1 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 FERM N-terminal domain DUF4504 PF14953.1 GAM27301.1 - 6e-08 32.3 0.1 2.2e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) Ras PF00071.17 GAM27302.1 - 1.6e-28 99.1 0.3 2.3e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27302.1 - 2.2e-09 37.8 0.0 5.3e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM27302.1 - 9.7e-05 21.6 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family EF-hand_1 PF00036.27 GAM27303.1 - 1.2e-36 121.1 11.2 2.9e-09 35.5 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 GAM27303.1 - 1.1e-33 115.1 2.9 9.6e-18 64.0 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM27303.1 - 2.5e-29 100.6 8.8 1.2e-15 56.8 0.5 3.6 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 GAM27303.1 - 4.6e-27 91.4 4.5 6.2e-08 31.8 0.0 4.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 GAM27303.1 - 1.2e-23 81.3 6.0 2.1e-05 23.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 GAM27303.1 - 5.3e-12 45.4 0.0 5.3e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 GAM27303.1 - 6.4e-10 39.0 0.0 0.00024 21.1 0.0 2.0 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAM27303.1 - 1.9e-08 33.9 0.5 0.0024 17.6 0.2 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 GAM27303.1 - 1.5e-07 30.9 0.0 0.00044 19.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 GAM27303.1 - 0.00036 20.4 0.1 0.00081 19.3 0.1 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Caleosin PF05042.8 GAM27303.1 - 0.0021 17.6 0.1 0.65 9.5 0.0 2.4 2 1 0 2 2 2 2 Caleosin related protein RNB PF00773.14 GAM27303.1 - 0.088 12.0 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 RNB domain Toprim_2 PF13155.1 GAM27303.1 - 0.13 12.5 0.8 8.7 6.7 0.4 2.7 1 1 1 2 2 2 0 Toprim-like RNA_pol_Rpb4 PF03874.11 GAM27303.1 - 0.13 12.2 1.2 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb4 Carb_kinase PF01256.12 GAM27304.1 - 3.5e-50 170.5 0.0 5.4e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 GAM27304.1 - 0.00034 19.8 0.3 0.00067 18.8 0.2 1.5 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 GAM27304.1 - 0.013 14.6 0.1 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase H_PPase PF03030.11 GAM27305.1 - 0.1 10.7 11.5 14 3.7 8.5 2.4 1 1 1 2 2 2 0 Inorganic H+ pyrophosphatase SMC_N PF02463.14 GAM27306.1 - 9.9e-20 70.7 20.5 9.2e-19 67.5 14.2 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAM27306.1 - 1.4e-07 32.0 34.7 1.4e-07 32.0 24.1 5.8 2 1 1 4 4 4 1 AAA domain AAA_13 PF13166.1 GAM27306.1 - 5.7e-07 28.4 66.0 0.0012 17.4 10.9 4.3 3 1 1 4 4 4 3 AAA domain AAA_21 PF13304.1 GAM27306.1 - 2.7e-05 24.2 16.8 0.00026 21.0 2.0 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 GAM27306.1 - 0.00054 19.4 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM27306.1 - 0.19 11.1 4.2 0.22 10.9 0.0 3.0 3 2 1 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 GAM27306.1 - 0.26 10.4 16.3 0.077 12.1 0.9 4.1 2 2 1 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 GAM27306.1 - 0.37 11.0 0.1 0.37 11.0 0.0 5.6 4 2 0 5 5 5 0 ABC transporter FUSC PF04632.7 GAM27306.1 - 9.7 4.4 6.1 2 6.7 1.4 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ras PF00071.17 GAM27307.1 - 3.1e-49 166.4 0.0 3.9e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27307.1 - 8.4e-19 68.2 0.0 1.2e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27307.1 - 1.5e-11 43.8 0.0 1.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM27307.1 - 5.6e-05 23.0 0.0 7.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM27307.1 - 8.6e-05 21.7 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM27307.1 - 0.0072 15.7 0.0 0.035 13.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 GAM27307.1 - 0.032 14.3 0.0 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 GAM27307.1 - 0.051 13.4 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 GAM27307.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CN_hydrolase PF00795.17 GAM27308.1 - 9.7e-19 67.4 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S8 PF00082.17 GAM27310.1 - 0.001 18.3 0.0 0.0021 17.2 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 GAM27311.1 - 4.5e-27 94.8 0.1 5.4e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain FNIP PF05725.7 GAM27312.1 - 2.7e-51 171.2 10.6 5.5e-12 45.4 0.0 8.9 5 2 2 9 9 9 8 FNIP Repeat I_LWEQ PF01608.12 GAM27313.1 - 4.9e-41 140.1 14.4 4.9e-41 140.1 10.0 17.3 7 6 10 19 19 19 7 I/LWEQ domain FERM_M PF00373.13 GAM27313.1 - 9e-23 80.8 0.5 9e-23 80.8 0.3 4.0 4 0 0 4 4 4 1 FERM central domain FERM_N PF09379.5 GAM27313.1 - 1.4e-13 50.6 0.1 2.5e-12 46.6 0.0 3.0 2 0 0 2 2 2 1 FERM N-terminal domain YukD PF08817.5 GAM27313.1 - 1.8e-05 25.2 0.0 0.002 18.6 0.0 3.5 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD IRS PF02174.12 GAM27313.1 - 5.7e-05 22.6 0.0 0.00019 20.9 0.0 1.9 1 0 0 1 1 1 1 PTB domain (IRS-1 type) VBS PF08913.5 GAM27313.1 - 6.7e-05 23.1 1.9 6.7e-05 23.1 1.3 12.7 11 4 0 12 12 12 5 Vinculin Binding Site BSD PF03909.12 GAM27313.1 - 0.048 13.4 2.2 1.1 9.0 0.0 3.2 2 0 0 2 2 2 0 BSD domain Sec7 PF01369.15 GAM27314.1 - 8.3e-49 165.8 5.6 8.3e-49 165.8 3.9 3.3 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.2 GAM27314.1 - 8e-42 142.5 4.9 8e-42 142.5 3.4 5.8 6 2 2 8 8 8 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAM27314.1 - 3.9e-27 93.5 0.9 3.9e-27 93.5 0.6 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) EB PF01683.13 GAM27315.1 - 0.0064 16.5 3.6 0.0064 16.5 2.5 3.3 1 1 2 3 3 3 2 EB module FA_desaturase PF00487.19 GAM27316.1 - 4.2e-42 144.3 17.9 4.5e-42 144.2 11.3 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 GAM27316.1 - 3.1e-25 87.7 0.1 1.5e-24 85.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.1 GAM27316.1 - 0.062 13.2 0.3 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Vma12 PF11712.3 GAM27316.1 - 0.14 11.8 0.4 0.34 10.6 0.2 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Dicty_CAR PF05462.6 GAM27317.1 - 5.2e-154 511.6 25.3 6.2e-154 511.3 17.5 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 GAM27317.1 - 3.1e-13 49.3 21.3 4.2e-13 48.9 14.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF1129 PF06570.6 GAM27317.1 - 0.011 15.0 0.8 0.011 15.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Git3_C PF11970.3 GAM27317.1 - 0.29 10.9 4.5 1.1 9.0 3.1 2.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term tRNA-synt_1b PF00579.20 GAM27318.1 - 1.2e-69 234.6 0.0 1.9e-69 233.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Inhibitor_I78 PF11720.3 GAM27318.1 - 0.041 13.6 0.0 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Peptidase inhibitor I78 family S4 PF01479.20 GAM27318.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.6 1 0 0 1 1 1 0 S4 domain FNIP PF05725.7 GAM27319.1 - 4.2e-92 301.8 35.5 2.7e-13 49.6 2.0 11.7 6 2 6 13 13 13 13 FNIP Repeat PWI PF01480.12 GAM27320.1 - 1.1e-13 51.0 0.7 1.1e-13 51.0 0.5 2.5 3 0 0 3 3 3 1 PWI domain RRM_1 PF00076.17 GAM27320.1 - 3.4e-10 39.4 0.0 7.9e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27320.1 - 2.7e-06 27.2 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27320.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Xpo1 PF08389.7 GAM27321.1 - 2.2 8.1 10.7 0.075 12.9 0.8 3.6 3 2 2 5 5 5 0 Exportin 1-like protein RRM_1 PF00076.17 GAM27322.1 - 3.2e-17 61.9 0.0 4.3e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27322.1 - 6e-16 58.1 0.0 7.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27322.1 - 1.5e-09 37.5 0.0 2.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM27322.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 GAM27323.1 - 3.4e-08 33.1 0.0 4.3e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM27323.1 - 0.00023 21.3 0.0 0.00029 20.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like AAA PF00004.24 GAM27324.1 - 1.2e-20 74.0 0.1 3.6e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM27324.1 - 0.00056 19.6 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM27324.1 - 0.0012 18.8 0.0 0.042 13.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Vps4_C PF09336.5 GAM27324.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 GAM27324.1 - 0.0046 16.0 0.0 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PPV_E1_C PF00519.12 GAM27324.1 - 0.0066 15.1 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase AAA_22 PF13401.1 GAM27324.1 - 0.013 15.6 0.0 1 9.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 GAM27324.1 - 0.051 12.4 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 GAM27324.1 - 0.078 11.8 0.0 0.19 10.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 GAM27324.1 - 0.078 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 GAM27324.1 - 0.092 13.5 0.0 0.54 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 GAM27325.1 - 1e-41 142.0 0.0 1.4e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27325.1 - 2.8e-17 63.3 0.0 6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 GAM27325.1 - 2.9e-05 23.4 0.1 0.00026 20.3 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 GAM27325.1 - 0.00022 21.1 0.0 0.00046 20.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 GAM27325.1 - 0.00029 20.1 0.0 0.00043 19.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family DNA_pol3_delta2 PF13177.1 GAM27325.1 - 0.0004 20.0 0.1 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 GAM27325.1 - 0.013 15.3 0.3 0.26 11.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 GAM27325.1 - 0.023 14.3 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.11 GAM27325.1 - 0.03 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF258 PF03193.11 GAM27325.1 - 0.03 13.4 0.0 0.069 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 GAM27325.1 - 0.032 13.9 0.5 0.33 10.6 0.2 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 GAM27325.1 - 0.039 14.0 0.1 2 8.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 GAM27325.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 GAM27325.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cNMP_binding PF00027.24 GAM27326.1 - 2.4e-26 91.3 0.1 3.5e-17 61.9 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.22 GAM27326.1 - 2.2e-16 60.1 0.0 4.9e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM27326.1 - 2.5e-10 40.2 0.2 7.6e-10 38.6 0.1 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 GAM27326.1 - 0.0073 16.0 0.0 0.039 13.6 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain ARID PF01388.16 GAM27327.1 - 3e-28 97.5 0.1 2.6e-27 94.5 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain SAP30_Sin3_bdg PF13867.1 GAM27327.1 - 2.6e-12 46.3 1.2 2.6e-12 46.3 0.8 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 FKBP_C PF00254.23 GAM27328.1 - 6.1e-24 83.8 0.2 6e-23 80.6 0.0 2.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase WH1 PF00568.18 GAM27328.1 - 4.4e-06 26.3 1.0 4.4e-06 26.3 0.7 2.3 2 0 0 2 2 2 1 WH1 domain DNA_repr_REX1B PF14966.1 GAM27328.1 - 3.7e-05 24.0 1.4 3.7e-05 24.0 1.0 3.9 3 1 1 5 5 5 1 DNA repair REX1-B Cyclin PF08613.6 GAM27329.1 - 0.24 11.7 3.5 0.47 10.8 2.4 1.6 1 1 0 1 1 1 0 Cyclin SpoVAE PF14097.1 GAM27330.1 - 0.13 11.6 0.2 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AE1 JAB PF01398.16 GAM27331.1 - 0.067 12.9 0.2 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Atrophin-1 PF03154.10 GAM27331.1 - 0.18 9.9 0.0 0.21 9.6 0.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family RhoGAP PF00620.22 GAM27332.1 - 2.7e-34 117.9 0.0 6.5e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LRR_6 PF13516.1 GAM27332.1 - 4.9e-08 32.2 26.9 0.00048 19.9 0.0 8.1 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 GAM27332.1 - 6e-05 22.5 24.6 0.21 11.2 0.0 6.6 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM27332.1 - 0.0053 16.6 10.6 4.2 7.7 0.0 7.0 6 1 0 6 6 6 1 Leucine Rich Repeat HSNSD PF12062.3 GAM27332.1 - 0.08 11.3 0.2 0.15 10.3 0.1 1.4 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase SNARE PF05739.14 GAM27333.1 - 9.6e-07 28.4 5.3 9.6e-07 28.4 3.7 2.0 2 0 0 2 2 2 1 SNARE domain Phage_GPL PF05926.6 GAM27333.1 - 0.0035 17.1 2.5 1 9.1 0.2 2.4 2 0 0 2 2 2 2 Phage head completion protein (GPL) Tropomyosin_1 PF12718.2 GAM27333.1 - 0.0061 16.4 0.7 0.0061 16.4 0.5 2.9 2 1 1 3 3 3 1 Tropomyosin like Rrn6 PF10214.4 GAM27333.1 - 0.021 12.9 0.1 0.024 12.7 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WXG100 PF06013.7 GAM27333.1 - 0.026 14.5 1.5 3.7 7.6 0.1 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF4047 PF13256.1 GAM27333.1 - 0.18 11.7 3.0 0.5 10.3 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4320 PF14208.1 GAM27333.1 - 0.23 11.3 1.3 0.62 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) HisKA PF00512.20 GAM27333.1 - 0.25 11.3 1.5 6.1 6.9 0.0 3.0 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Laminin_II PF06009.7 GAM27333.1 - 1.8 8.3 14.2 0.061 13.0 1.1 3.0 1 1 1 3 3 3 0 Laminin Domain II MFS_1 PF07690.11 GAM27334.1 - 4.8e-67 226.1 29.1 3.1e-44 151.1 5.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 GAM27334.1 - 1.2e-14 53.5 28.3 1.1e-07 30.5 6.5 3.3 1 1 2 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 GAM27334.1 - 1.7e-13 50.0 21.6 2.2e-12 46.3 14.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 GAM27334.1 - 5.9e-08 31.2 10.6 1.2e-06 27.0 5.4 2.2 1 1 1 2 2 2 2 Transmembrane secretion effector LacY_symp PF01306.14 GAM27334.1 - 3.9e-05 22.3 24.9 5.2e-05 21.9 1.2 3.6 3 1 0 3 3 3 2 LacY proton/sugar symporter MFS_1_like PF12832.2 GAM27334.1 - 7.4e-05 22.4 9.1 0.018 14.8 0.9 3.6 3 0 0 3 3 3 2 MFS_1 like family DUF2633 PF11119.3 GAM27334.1 - 0.019 14.6 0.0 0.13 12.0 0.0 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) OATP PF03137.15 GAM27334.1 - 0.83 7.6 23.6 0.0084 14.2 1.5 3.8 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_YMGG PF13441.1 GAM27334.1 - 1 8.9 4.6 2.3 7.7 3.2 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 GAM27334.1 - 1.2 8.8 5.3 7.8 6.2 4.0 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 GAM27334.1 - 2 8.1 7.3 4.9 6.8 4.5 2.0 2 0 0 2 2 2 0 Glycine zipper NAD_binding_4 PF07993.7 GAM27335.1 - 9.3e-60 201.6 0.0 1.6e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 GAM27335.1 - 1.1e-22 79.8 0.0 3.1e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.14 GAM27335.1 - 1.5e-09 37.9 0.2 4.6e-09 36.4 0.2 1.9 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 GAM27335.1 - 2e-08 33.9 0.0 6.3e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM27335.1 - 1.4e-05 23.9 0.5 0.00019 20.2 0.3 2.6 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Aldedh PF00171.17 GAM27336.1 - 4.3e-133 444.0 0.3 4.9e-133 443.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SCAMP PF04144.8 GAM27337.1 - 1.1e-15 57.9 15.5 1.4e-15 57.6 10.7 1.1 1 0 0 1 1 1 1 SCAMP family HAMP PF00672.20 GAM27337.1 - 0.49 10.6 0.1 0.49 10.6 0.1 2.0 2 0 0 2 2 2 0 HAMP domain DUF4131 PF13567.1 GAM27337.1 - 3.9 6.8 9.5 0.64 9.4 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) TPR_1 PF00515.23 GAM27338.1 - 2.8e-10 39.3 0.2 0.00032 20.1 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM27338.1 - 4.2e-09 35.9 0.0 3.3e-08 33.0 0.0 2.3 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 GAM27338.1 - 2.1e-08 33.4 0.0 0.001 18.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM27338.1 - 2.5e-05 24.1 0.0 0.013 15.3 0.0 2.5 1 1 2 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.19 GAM27338.1 - 2.5e-05 23.8 0.2 4.6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.1 GAM27338.1 - 9.3e-05 21.9 0.0 0.05 13.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat WW PF00397.21 GAM27338.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 WW domain TPR_6 PF13174.1 GAM27338.1 - 0.012 16.0 0.0 12 6.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 GAM27338.1 - 0.12 12.2 0.0 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM27338.1 - 0.13 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MFS_1 PF07690.11 GAM27339.1 - 8.2e-44 149.7 47.3 5.4e-36 124.0 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM27339.1 - 3.2e-08 32.5 34.2 0.00011 20.9 9.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAM27339.1 - 1.5e-07 30.1 24.0 0.00035 19.0 3.1 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 GAM27339.1 - 0.0014 18.3 0.3 0.51 10.1 0.0 3.1 2 0 0 2 2 2 2 MFS_1 like family Ocular_alb PF02101.10 GAM27339.1 - 0.0019 16.8 0.1 0.0042 15.7 0.1 1.6 1 0 0 1 1 1 1 Ocular albinism type 1 protein RabGAP-TBC PF00566.13 GAM27340.1 - 2.4e-22 79.4 7.9 1.6e-19 70.2 4.2 2.5 2 1 0 2 2 2 2 Rab-GTPase-TBC domain DUF4014 PF13198.1 GAM27340.1 - 0.052 13.9 0.3 0.16 12.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DUF3439 PF11921.3 GAM27340.1 - 0.56 9.9 7.1 1.1 8.9 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EGF_CA PF07645.10 GAM27341.1 - 6.1e-20 70.9 43.2 2e-08 34.0 6.1 7.5 6 1 1 7 7 7 3 Calcium-binding EGF domain cEGF PF12662.2 GAM27341.1 - 2.9e-09 36.3 15.0 1e-06 28.2 2.5 6.5 6 1 0 6 6 6 3 Complement Clr-like EGF-like TIG PF01833.19 GAM27341.1 - 5.9e-06 26.1 2.2 5.9e-06 26.1 1.5 5.5 4 2 0 4 4 4 2 IPT/TIG domain EGF_MSP1_1 PF12946.2 GAM27341.1 - 4.5e-05 23.1 2.8 4.5e-05 23.1 2.0 5.5 5 0 0 5 5 5 1 MSP1 EGF domain 1 EGF_3 PF12947.2 GAM27341.1 - 4.7e-05 23.2 20.3 0.0008 19.3 4.8 6.0 5 0 0 5 5 5 3 EGF domain FXa_inhibition PF14670.1 GAM27341.1 - 0.0032 17.5 9.5 0.0032 17.5 6.6 6.0 5 1 0 5 5 5 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 GAM27341.1 - 0.011 15.6 5.0 0.011 15.6 3.5 6.0 5 0 0 5 5 5 0 EGF-like domain hEGF PF12661.2 GAM27341.1 - 0.7 10.1 31.4 0.38 10.9 0.9 5.2 5 0 0 5 5 5 0 Human growth factor-like EGF DAGAT PF03982.8 GAM27342.1 - 1.3e-105 352.3 0.0 1.5e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF1765 PF08578.5 GAM27343.1 - 0.059 13.4 0.9 0.74 9.8 0.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1765) Mannosyl_trans PF05007.8 GAM27344.1 - 3.2e-80 269.5 32.0 5.6e-80 268.7 22.2 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 GAM27344.1 - 0.0012 18.4 0.4 0.0012 18.4 0.3 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 GAM27344.1 - 0.0015 17.5 37.9 1.7 7.4 22.7 3.3 1 1 1 2 2 2 2 GPI transamidase subunit PIG-U DUF2663 PF10864.3 GAM27345.1 - 1.6 8.9 7.2 5.8 7.1 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) BAR PF03114.13 GAM27346.1 - 9.6e-20 71.0 6.5 1.6e-19 70.3 4.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 GAM27346.1 - 6.3e-10 38.2 0.0 1.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM27346.1 - 3.6e-09 36.0 0.0 6.4e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM27346.1 - 3.5e-08 32.8 0.0 5.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.8 GAM27346.1 - 0.016 14.5 3.9 0.52 9.6 2.7 2.4 1 1 0 1 1 1 0 Arfaptin-like domain THOC7 PF05615.8 GAM27346.1 - 0.37 11.0 4.7 0.67 10.2 3.3 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 PAT1 PF09770.4 GAM27346.1 - 7.5 4.6 26.7 12 3.9 18.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCHC PF00098.18 GAM27347.1 - 2.3e-31 106.1 45.6 5.3e-08 32.4 0.9 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 GAM27347.1 - 5.7e-06 25.9 32.4 0.042 13.5 1.0 5.1 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.1 GAM27347.1 - 3.7e-05 23.3 34.2 0.68 9.7 1.0 5.1 3 2 2 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.1 GAM27347.1 - 0.00062 19.3 38.1 0.029 14.0 2.4 5.0 4 1 1 5 5 5 3 Zinc knuckle APC10 PF03256.11 GAM27348.1 - 5.3e-56 189.2 0.2 6e-56 189.1 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 GAM27348.1 - 0.00017 21.4 0.1 0.00025 20.8 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.8 GAM27348.1 - 0.096 12.4 0.1 0.19 11.5 0.0 1.7 2 1 0 2 2 2 0 Sad1 / UNC-like C-terminal JmjC PF02373.17 GAM27350.1 - 3.6e-37 127.0 1.9 7.9e-37 125.9 0.1 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 GAM27350.1 - 7.9e-20 70.5 0.1 1.7e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 GAM27350.1 - 7.8e-17 60.4 1.9 1.5e-16 59.5 1.3 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 GAM27351.1 - 0.01 15.8 16.3 0.063 13.3 11.3 2.1 1 1 0 1 1 1 0 C5HC2 zinc finger SSFA2_C PF14723.1 GAM27351.1 - 0.011 15.4 1.1 0.011 15.4 0.7 1.6 1 1 1 2 2 2 0 Sperm-specific antigen 2 C-terminus Dicty_REP PF05086.7 GAM27351.1 - 0.11 10.2 8.6 0.14 9.8 6.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S76 PF13611.1 GAM27351.1 - 0.37 10.8 2.5 1.6 8.8 0.4 2.1 2 0 0 2 2 2 0 Serine peptidase of plant viral polyprotein, P1 FNIP PF05725.7 GAM27353.1 - 1.2e-73 242.8 8.4 9.4e-11 41.4 0.0 10.6 4 4 5 11 11 11 10 FNIP Repeat LRR_8 PF13855.1 GAM27353.1 - 0.016 14.9 1.8 5.3 6.8 0.0 4.5 2 2 1 3 3 3 0 Leucine rich repeat FNIP PF05725.7 GAM27354.1 - 1.2e-18 66.8 8.1 6.4e-06 26.0 0.2 6.8 3 2 5 8 8 8 5 FNIP Repeat LRR_6 PF13516.1 GAM27354.1 - 0.35 11.0 7.5 3.1 8.1 0.1 5.0 4 0 0 4 4 4 0 Leucine Rich repeat DUF4363 PF14276.1 GAM27355.1 - 0.005 16.5 0.2 0.0097 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) Peptidase_S49_N PF08496.5 GAM27355.1 - 0.013 15.3 2.1 0.013 15.3 1.5 1.7 1 1 0 2 2 2 0 Peptidase family S49 N-terminal LemA PF04011.7 GAM27355.1 - 0.051 12.6 0.2 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 LemA family Retrotrans_gag PF03732.12 GAM27355.1 - 0.086 12.9 1.1 0.26 11.3 0.8 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein DivIC PF04977.10 GAM27355.1 - 0.12 11.8 0.1 0.12 11.8 0.0 3.2 4 0 0 4 4 4 0 Septum formation initiator SET PF00856.23 GAM27356.1 - 3.7e-10 40.3 0.2 0.00039 20.7 0.0 2.4 1 1 1 2 2 2 2 SET domain Ank PF00023.25 GAM27356.1 - 1.3e-08 34.1 0.1 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAM27356.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM27356.1 - 9e-05 22.5 0.0 0.00083 19.5 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM27356.1 - 0.00049 20.5 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27356.1 - 0.0016 18.4 0.1 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat SAF PF08666.7 GAM27356.1 - 0.051 13.9 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 SAF domain Med1 PF10744.4 GAM27357.1 - 1.1e-10 40.9 2.3 3.5e-10 39.2 0.1 2.7 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 G-patch PF01585.18 GAM27358.1 - 6.8e-11 41.7 0.2 1.7e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM27358.1 - 5.4e-08 32.5 0.2 1.4e-07 31.2 0.2 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_1 PF00076.17 GAM27358.1 - 9.3e-06 25.1 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27358.1 - 1.3e-05 25.0 0.0 3.5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 GAM27358.1 - 0.0079 16.3 0.5 0.022 14.8 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 GAM27358.1 - 0.0092 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 GAM27358.1 - 0.011 16.0 1.5 0.028 14.7 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.9 GAM27358.1 - 0.016 14.8 1.3 0.086 12.4 0.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-met PF12874.2 GAM27358.1 - 0.017 15.2 0.0 0.057 13.6 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 GAM27358.1 - 0.042 13.7 0.1 0.042 13.7 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Cupin_8 PF13621.1 GAM27360.1 - 1.9e-12 47.2 1.2 4.3e-11 42.7 0.0 2.8 3 1 0 3 3 3 1 Cupin-like domain zf-H2C2_5 PF13909.1 GAM27360.1 - 0.057 13.6 1.2 0.16 12.2 0.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF498 PF04430.9 GAM27361.1 - 1.1e-15 57.0 0.0 2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) EF-hand_7 PF13499.1 GAM27362.1 - 1.8e-19 69.6 11.7 1.7e-05 24.8 0.0 4.1 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAM27362.1 - 1.8e-17 61.1 13.8 2.9e-05 23.0 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 GAM27362.1 - 6e-17 59.9 9.3 0.00055 19.6 0.0 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 GAM27362.1 - 1.7e-13 49.9 14.1 0.00013 21.5 1.3 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM27362.1 - 1.4e-10 39.9 10.5 1.2e-07 30.7 0.0 4.2 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 GAM27362.1 - 0.00012 22.1 2.2 0.64 10.0 0.0 3.3 1 1 2 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region NADPH_Ox PF08414.5 GAM27362.1 - 0.0031 17.5 0.3 0.33 11.0 0.1 2.4 1 1 1 2 2 2 1 Respiratory burst NADPH oxidase EF-hand_4 PF12763.2 GAM27362.1 - 0.02 14.6 3.2 0.03 14.0 0.2 2.7 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand Cullin_binding PF03556.10 GAM27362.1 - 0.029 14.4 0.2 3.6 7.7 0.0 2.2 1 1 1 2 2 2 0 Cullin binding DUF1829 PF08862.5 GAM27362.1 - 0.13 12.5 0.9 0.36 11.1 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Cyclin_N PF00134.18 GAM27363.1 - 1.2e-08 34.5 0.6 2.3e-08 33.6 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain EVE PF01878.13 GAM27363.1 - 0.0003 20.8 0.3 0.0014 18.7 0.0 2.2 2 0 0 2 2 2 1 EVE domain DUF1627 PF07789.7 GAM27363.1 - 0.18 11.3 0.7 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) DUF410 PF04190.8 GAM27364.1 - 2.1e-52 178.2 0.0 2.7e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) VWA_2 PF13519.1 GAM27366.1 - 7.9e-18 65.1 0.0 2.6e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain ubiquitin PF00240.18 GAM27366.1 - 3.6e-08 32.6 0.1 9.8e-08 31.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Ras PF00071.17 GAM27366.1 - 8e-07 28.5 1.5 1.3e-05 24.6 0.0 3.0 3 0 0 3 3 3 1 Ras family Miro PF08477.8 GAM27366.1 - 2.6e-05 24.7 6.0 0.011 16.2 0.1 3.2 2 1 1 3 3 3 2 Miro-like protein Rad60-SLD PF11976.3 GAM27366.1 - 0.001 18.7 0.1 0.0026 17.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like VWA_3 PF13768.1 GAM27366.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Orthopox_F8 PF05886.6 GAM27366.1 - 0.017 14.9 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Orthopoxvirus F8 protein YscJ_FliF PF01514.12 GAM27366.1 - 0.15 11.1 2.2 0.28 10.3 0.0 2.4 3 0 0 3 3 3 0 Secretory protein of YscJ/FliF family FNIP PF05725.7 GAM27367.1 - 5e-63 208.8 17.5 3.3e-12 46.1 0.5 7.3 4 2 3 7 7 7 7 FNIP Repeat LRR_5 PF13306.1 GAM27367.1 - 3e-06 26.9 0.9 0.3 10.8 0.0 3.6 1 1 1 3 3 3 2 Leucine rich repeats (6 copies) Utp12 PF04003.7 GAM27369.1 - 1e-07 31.8 0.6 1.6e-07 31.2 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family TEX12 PF15219.1 GAM27369.1 - 0.12 12.4 0.6 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 Testis-expressed 12 TEX15 PF15326.1 GAM27369.1 - 0.82 9.2 3.9 1.2 8.6 2.7 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 Beta_helix PF13229.1 GAM27370.1 - 0.00063 19.5 115.6 0.0097 15.6 16.1 6.9 2 1 5 7 7 7 5 Right handed beta helix region Tubulin PF00091.20 GAM27371.1 - 9.2e-72 241.3 0.0 1.4e-71 240.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 GAM27371.1 - 7.6e-48 161.7 0.2 1.3e-47 161.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 GAM27371.1 - 5.2e-08 32.9 0.0 1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 GAM27371.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain EGF_2 PF07974.8 GAM27372.1 - 0.59 10.3 7.8 1.6 8.9 5.4 1.7 1 0 0 1 1 1 0 EGF-like domain Kelch_4 PF13418.1 GAM27373.1 - 2.1e-46 155.4 14.2 3.9e-09 36.1 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM27373.1 - 8.1e-45 150.0 18.3 3.2e-10 39.8 0.5 7.5 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM27373.1 - 4e-36 122.2 16.1 5.5e-07 29.0 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM27373.1 - 2.3e-34 116.1 15.5 7.9e-07 28.9 0.2 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_5 PF13854.1 GAM27373.1 - 1.5e-32 111.0 15.9 4.4e-08 32.8 0.1 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.26 GAM27373.1 - 7.7e-25 87.0 1.4 4.6e-23 81.3 0.2 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.10 GAM27373.1 - 2.5e-20 71.3 10.7 0.00052 19.6 0.1 6.3 6 0 0 6 6 6 5 Kelch motif MoeZ_MoeB PF05237.8 GAM27373.1 - 0.12 11.9 0.0 6.3 6.4 0.0 2.7 3 0 0 3 3 3 0 MoeZ/MoeB domain DKCLD PF08068.7 GAM27374.1 - 3e-32 110.3 0.3 4.5e-31 106.5 0.2 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.15 GAM27374.1 - 1.6e-20 72.6 1.1 3.1e-20 71.6 0.8 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.13 GAM27374.1 - 6.7e-20 71.7 0.3 6.7e-20 71.7 0.2 5.0 2 2 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) PolyA_pol PF01743.15 GAM27376.1 - 1.7e-21 76.7 0.2 1.7e-21 76.7 0.1 2.1 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 GAM27376.1 - 0.0026 17.2 0.0 0.0085 15.6 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Cyt-b5 PF00173.23 GAM27377.1 - 3.3e-13 49.2 0.0 4.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RTC PF01137.16 GAM27378.1 - 2.8e-74 248.7 0.3 3.4e-74 248.4 0.2 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 GAM27378.1 - 8.1e-21 73.9 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CobS_N PF12556.3 GAM27378.1 - 0.098 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal DbpA PF03880.10 GAM27378.1 - 0.13 11.9 0.8 0.26 10.9 0.5 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain Apc5 PF12862.2 GAM27379.1 - 8.1e-29 99.3 8.9 9.1e-29 99.1 4.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 GAM27379.1 - 1.1e-10 41.2 15.9 0.015 15.2 0.4 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM27379.1 - 5.3e-06 25.8 6.7 0.26 11.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 GAM27379.1 - 2e-05 24.1 9.1 4.2 7.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM27379.1 - 0.00044 20.5 1.6 0.93 9.8 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM27379.1 - 0.00072 19.9 0.6 3.3 8.5 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM27379.1 - 0.0011 19.5 0.9 0.56 10.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM27379.1 - 0.0026 17.3 9.4 0.077 12.6 0.1 4.9 6 0 0 6 6 6 1 TPR repeat HisG PF01634.13 GAM27379.1 - 0.019 14.5 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 ATP phosphoribosyltransferase TPR_1 PF00515.23 GAM27379.1 - 0.049 13.2 7.1 2.3 7.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM27379.1 - 0.08 12.7 0.9 32 4.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 GAM27379.1 - 0.15 12.2 13.5 0.87 9.7 0.6 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM27379.1 - 0.45 11.0 2.9 2.4 8.8 0.0 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TatD_DNase PF01026.16 GAM27380.1 - 1e-56 192.0 0.1 1.9e-56 191.1 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase Amidohydro_2 PF04909.9 GAM27380.1 - 4.8e-06 26.3 0.1 8.4e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase Gemini_AL1_M PF08283.6 GAM27380.1 - 0.02 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Geminivirus rep protein central domain SR-25 PF10500.4 GAM27380.1 - 0.046 13.1 2.4 0.07 12.5 1.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_L1 PF00687.16 GAM27381.1 - 9e-49 165.7 5.3 1.1e-48 165.5 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Alpha-2-MRAP_C PF06401.6 GAM27381.1 - 0.0036 17.1 0.6 0.0059 16.4 0.4 1.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain Pkinase PF00069.20 GAM27383.1 - 5.7e-24 84.6 0.1 3.2e-23 82.1 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain WD40 PF00400.27 GAM27383.1 - 5.4e-22 76.8 8.0 8.5e-08 31.8 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 GAM27383.1 - 1e-10 41.1 0.0 2.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 GAM27383.1 - 6.4e-05 22.7 0.1 0.18 11.9 0.1 4.2 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 GAM27383.1 - 0.00034 20.8 0.0 3.2 8.1 0.0 3.6 2 2 1 3 3 3 3 HEAT repeats APH PF01636.18 GAM27383.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coiled PF05710.7 GAM27384.1 - 1.9e-09 37.8 17.7 2.1e-09 37.7 12.3 1.0 1 0 0 1 1 1 1 Coiled coil PRMT5 PF05185.11 GAM27385.1 - 1.2e-12 47.5 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 GAM27385.1 - 6.4e-10 39.6 0.1 2e-09 38.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 GAM27385.1 - 1.4e-09 37.5 0.1 1.9e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 GAM27385.1 - 7.2e-08 32.1 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM27385.1 - 8.5e-08 32.5 0.2 8.2e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM27385.1 - 3.3e-07 30.1 0.0 5.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 GAM27385.1 - 1.6e-05 24.6 0.2 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 GAM27385.1 - 1.9e-05 24.1 0.1 3.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 GAM27385.1 - 4.5e-05 23.8 0.0 0.00016 22.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM27385.1 - 0.0002 21.3 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM27385.1 - 0.00067 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 GAM27385.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 GAM27385.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 GAM27385.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_21 PF05050.7 GAM27385.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase FkbM domain RasGEF PF00617.14 GAM27386.1 - 3.1e-55 186.8 1.3 5.8e-55 185.9 0.9 1.4 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.24 GAM27386.1 - 2e-23 81.9 0.1 6.1e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.15 GAM27386.1 - 4e-15 55.7 0.8 1.5e-14 53.9 0.6 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif GRAM PF02893.15 GAM27386.1 - 2.4e-13 49.3 0.3 9e-13 47.5 0.1 2.1 2 0 0 2 2 2 1 GRAM domain bPH_3 PF14470.1 GAM27386.1 - 0.0012 19.1 0.1 0.0047 17.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial PH domain DUF4414 PF14377.1 GAM27386.1 - 0.043 13.7 0.6 0.09 12.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Vps36_ESCRT-II PF11605.3 GAM27386.1 - 0.086 12.6 0.5 2 8.2 0.0 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Takusan PF04822.8 GAM27387.1 - 0.064 13.0 0.2 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Takusan Coq4 PF05019.8 GAM27389.1 - 1.3e-79 266.1 0.0 1.7e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 E1_DerP2_DerF2 PF02221.10 GAM27390.1 - 9.5e-21 74.4 0.2 1.1e-20 74.1 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 GAM27390.1 - 7.4e-05 22.8 0.7 0.00041 20.4 0.5 1.9 1 1 0 1 1 1 1 ML-like domain BPL_LplA_LipB PF03099.14 GAM27391.1 - 1.4e-17 63.8 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 GAM27391.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain RhoGEF PF00621.15 GAM27392.1 - 4.8e-31 108.0 0.0 1.3e-30 106.6 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain DnaJ PF00226.26 GAM27393.1 - 4.2e-07 29.5 0.1 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain PCEMA1 PF07418.6 GAM27393.1 - 0.027 13.8 7.9 0.037 13.4 5.5 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 CDC45 PF02724.9 GAM27393.1 - 0.032 12.2 6.4 0.037 12.0 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 GAM27393.1 - 0.062 12.5 4.0 0.083 12.1 2.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CENP-B_dimeris PF09026.5 GAM27393.1 - 0.19 11.9 12.6 0.089 13.0 6.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.5 GAM27393.1 - 0.2 10.7 10.6 0.12 11.4 5.2 1.8 2 0 0 2 2 2 0 BUD22 DUF1510 PF07423.6 GAM27393.1 - 0.3 10.4 7.4 0.43 9.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 GAM27393.1 - 0.32 10.4 6.1 0.5 9.8 4.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.6 GAM27393.1 - 0.64 9.5 17.1 1.1 8.7 11.9 1.3 1 0 0 1 1 1 0 PPP4R2 Na_trans_assoc PF06512.8 GAM27393.1 - 0.92 9.4 8.6 3.7 7.4 3.9 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated SDA1 PF05285.7 GAM27393.1 - 1 8.5 9.6 1.5 8.0 6.7 1.2 1 0 0 1 1 1 0 SDA1 Paramyxo_ncap PF00973.14 GAM27393.1 - 1.1 7.8 4.1 1.5 7.3 2.8 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NOA36 PF06524.7 GAM27393.1 - 1.6 7.8 11.7 2.2 7.4 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 GAM27393.1 - 2.7 7.6 16.3 4.5 6.9 11.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.2 GAM27393.1 - 3.4 5.2 10.0 3.9 5.0 6.5 1.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DivIC PF04977.10 GAM27393.1 - 3.8 7.0 8.5 8.6 5.9 5.9 1.6 1 0 0 1 1 1 0 Septum formation initiator Cwf_Cwc_15 PF04889.7 GAM27396.1 - 6.8e-48 163.5 42.9 8e-48 163.2 29.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF966 PF06136.8 GAM27396.1 - 0.011 15.1 22.9 0.014 14.8 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BUD22 PF09073.5 GAM27396.1 - 0.11 11.5 44.4 0.15 11.0 30.8 1.2 1 0 0 1 1 1 0 BUD22 Tir_receptor_C PF07489.6 GAM27396.1 - 0.73 9.5 10.7 1.7 8.3 7.4 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus FNIP PF05725.7 GAM27397.1 - 5.2e-55 183.1 7.8 1.1e-13 50.8 0.0 7.6 7 1 0 8 8 8 7 FNIP Repeat TRAP_alpha PF03896.11 GAM27397.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Beta-Casp PF10996.3 GAM27399.1 - 2.7e-23 82.2 0.0 7.1e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 GAM27399.1 - 4.8e-16 58.2 0.0 1.5e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 GAM27399.1 - 0.0034 17.0 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 GAM27399.1 - 0.058 12.9 0.7 1.5 8.3 0.0 2.6 2 1 0 2 2 2 0 Beta-lactamase superfamily domain TSC22 PF01166.13 GAM27401.1 - 0.0017 18.2 0.5 0.0033 17.3 0.4 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF1395 PF07160.7 GAM27401.1 - 0.033 13.6 1.3 0.037 13.5 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) SNARE_assoc PF09335.6 GAM27402.1 - 1.6e-17 63.8 10.3 3e-17 62.9 7.1 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein TILa PF12714.2 GAM27403.1 - 0.0032 17.2 95.1 0.17 11.6 0.6 12.1 9 1 3 12 12 12 10 TILa domain DUF3990 PF13151.1 GAM27403.1 - 0.76 9.1 1.6 15 4.9 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3990) SR-25 PF10500.4 GAM27404.1 - 0.014 14.9 3.4 0.027 13.9 2.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 GAM27404.1 - 0.057 12.7 6.8 0.21 10.9 0.9 2.4 2 0 0 2 2 2 0 Spt20 family FAM60A PF15396.1 GAM27404.1 - 0.15 11.7 4.2 0.94 9.1 2.3 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF423 PF04241.10 GAM27405.1 - 1.5e-26 92.0 0.7 2.1e-26 91.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Rubis-subs-bind PF09273.6 GAM27406.1 - 1.7e-18 66.7 0.0 3.8e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 GAM27406.1 - 3.5e-08 33.9 0.0 0.0048 17.2 0.0 2.7 2 0 0 2 2 2 2 SET domain Ribosomal_L19e PF01280.15 GAM27407.1 - 5.4e-13 48.9 0.0 6.3e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e HTH_17 PF12728.2 GAM27407.1 - 0.03 14.5 0.1 7.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain RhoGEF PF00621.15 GAM27408.1 - 2.3e-51 174.2 1.0 4.2e-51 173.3 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.26 GAM27408.1 - 1.4e-15 57.2 1.2 9.4e-15 54.5 0.0 2.8 3 0 0 3 3 3 1 Calponin homology (CH) domain CDC24 PF06395.6 GAM27408.1 - 7.1e-05 22.7 0.1 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 CDC24 Calponin IQ PF00612.22 GAM27408.1 - 0.028 14.0 0.0 0.072 12.7 0.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif HTH_45 PF14947.1 GAM27408.1 - 0.034 13.9 1.4 0.087 12.6 0.1 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix PH PF00169.24 GAM27408.1 - 0.097 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 PH domain Myb_DNA-binding PF00249.26 GAM27409.1 - 1.1e-23 83.0 8.6 1.9e-11 43.8 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM27409.1 - 4.4e-21 74.7 8.2 4.6e-14 52.2 0.9 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Prok-RING_1 PF14446.1 GAM27409.1 - 0.00011 21.8 4.6 0.00026 20.6 3.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Daxx PF03344.10 GAM27409.1 - 0.002 16.7 9.1 0.002 16.7 6.3 3.3 2 1 1 3 3 3 1 Daxx Family PHD PF00628.24 GAM27409.1 - 0.0029 17.2 8.5 0.009 15.6 5.9 1.9 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 GAM27409.1 - 0.013 14.7 7.2 0.038 13.3 5.0 1.9 1 0 0 1 1 1 0 PHD-finger FYVE_2 PF02318.11 GAM27409.1 - 7.9 6.4 13.2 0.036 13.9 2.5 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger LysM PF01476.15 GAM27410.1 - 0.031 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain Sulfate_transp PF00916.15 GAM27411.1 - 1.2e-60 204.8 15.2 1.2e-60 204.8 10.6 2.1 1 1 1 2 2 2 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 GAM27411.1 - 5.8e-33 112.4 4.5 1.1e-32 111.5 2.0 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 GAM27411.1 - 1.1e-17 63.4 0.1 2e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 STAS domain GATase PF00117.23 GAM27413.1 - 4.1e-09 36.1 0.2 3.5e-08 33.1 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 GAM27413.1 - 0.00025 20.6 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 GAM27413.1 - 0.0025 17.2 0.0 0.0074 15.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 DUF2576 PF10845.3 GAM27413.1 - 0.11 11.7 1.1 2.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) UQ_con PF00179.21 GAM27414.1 - 5.7e-47 158.6 0.0 6.5e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM27414.1 - 0.00048 19.8 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 GAM27414.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.6 1 1 0 1 1 1 0 UEV domain SapB_1 PF05184.10 GAM27415.1 - 7.1e-11 41.6 13.3 6.5e-07 29.0 0.2 3.5 3 1 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 GAM27415.1 - 0.0081 16.1 0.0 0.0081 16.1 0.0 3.3 4 0 0 4 4 4 1 Saposin-like type B, region 2 TRAPP PF04051.11 GAM27416.1 - 1e-36 125.7 0.3 1.3e-36 125.3 0.2 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cellulose_synt PF03552.9 GAM27417.1 - 0.075 11.3 1.2 0.12 10.5 0.8 1.3 1 0 0 1 1 1 0 Cellulose synthase Glypican PF01153.14 GAM27417.1 - 1.4 7.4 7.0 2.4 6.6 4.9 1.3 1 0 0 1 1 1 0 Glypican Daxx PF03344.10 GAM27417.1 - 2.5 6.4 20.9 3.4 6.0 14.5 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 GAM27417.1 - 5.3 5.5 10.2 6.5 5.2 7.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ank PF00023.25 GAM27418.1 - 8.3e-06 25.3 0.1 2.5e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 GAM27418.1 - 6.8e-05 23.2 0.0 0.00044 20.6 0.0 2.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM27418.1 - 0.0091 16.3 0.0 0.03 14.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM27418.1 - 0.0099 16.0 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 GAM27418.1 - 0.01 16.0 0.0 0.17 12.1 0.0 2.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) PAT1 PF09770.4 GAM27418.1 - 0.011 14.0 92.1 0.034 12.4 16.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 IGR PF09597.5 GAM27419.1 - 3.2e-22 78.1 0.1 5.2e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif Methyltransf_7 PF03492.10 GAM27420.1 - 1.1e-37 129.5 0.2 1.3e-37 129.2 0.1 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase RabGAP-TBC PF00566.13 GAM27421.1 - 6.3e-26 91.1 1.0 6.3e-26 91.1 0.7 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SDA1 PF05285.7 GAM27421.1 - 0.49 9.6 14.2 0.66 9.1 9.8 1.1 1 0 0 1 1 1 0 SDA1 DUF962 PF06127.6 GAM27422.1 - 4.5e-21 74.5 10.7 3e-20 71.8 7.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Alpha_L_fucos PF01120.12 GAM27423.1 - 4e-108 361.4 6.4 5.2e-108 361.0 4.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase NAD_binding_6 PF08030.7 GAM27424.1 - 1e-32 113.2 0.0 1.5e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM27424.1 - 8.9e-18 64.1 0.0 2.3e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAM27424.1 - 1.3e-16 60.8 9.2 3.3e-16 59.5 6.4 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAM27424.1 - 1.9e-05 24.7 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM27424.1 - 0.0049 17.4 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain zf-C2H2_4 PF13894.1 GAM27425.1 - 0.0065 16.7 1.0 0.0065 16.7 0.7 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 GAM27425.1 - 0.0079 16.2 0.6 0.0079 16.2 0.4 2.5 2 1 1 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 GAM27425.1 - 0.01 16.1 1.1 0.01 16.1 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Baculo_11_kDa PF06143.6 GAM27425.1 - 0.019 14.3 1.4 0.28 10.5 0.1 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family BatD PF13584.1 GAM27425.1 - 0.032 12.8 0.4 0.058 11.9 0.3 1.4 1 0 0 1 1 1 0 Oxygen tolerance GP41 PF00517.12 GAM27425.1 - 0.037 13.5 0.2 0.037 13.5 0.2 2.3 3 1 0 3 3 3 0 Retroviral envelope protein Allene_ox_cyc PF06351.6 GAM27425.1 - 0.042 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Allene oxide cyclase RDD PF06271.7 GAM27425.1 - 0.061 13.2 0.2 0.11 12.3 0.0 1.5 2 0 0 2 2 2 0 RDD family SUR7 PF06687.7 GAM27425.1 - 0.077 12.5 0.8 0.099 12.1 0.2 1.6 2 0 0 2 2 2 0 SUR7/PalI family zf-C2H2_jaz PF12171.3 GAM27425.1 - 0.62 10.2 8.6 0.13 12.4 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM27425.1 - 2.2 8.6 6.1 1 9.6 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ABC2_membrane_3 PF12698.2 GAM27425.1 - 2.4 7.1 5.3 11 4.9 3.7 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Ribosomal_L7Ae PF01248.21 GAM27426.1 - 7.6e-22 76.6 4.6 2.7e-21 74.8 3.2 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 GAM27426.1 - 0.0015 18.3 0.1 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF496 PF04363.7 GAM27426.1 - 0.0085 15.8 0.6 0.012 15.3 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF496) RCR PF12273.3 GAM27427.1 - 0.11 13.0 2.4 0.19 12.2 1.7 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Pkinase PF00069.20 GAM27428.1 - 1.6e-52 178.2 0.2 9.7e-52 175.6 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27428.1 - 1.7e-23 83.0 0.3 1.4e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM27428.1 - 1e-05 24.6 0.1 0.093 11.6 0.0 3.2 3 0 0 3 3 3 2 Kinase-like WaaY PF06176.6 GAM27428.1 - 0.08 12.1 0.1 12 5.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 GAM27428.1 - 0.12 11.2 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1117 PF06547.7 GAM27428.1 - 3 7.9 10.4 0.26 11.3 3.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) Cna_B PF05738.8 GAM27430.1 - 3.9e-20 71.3 11.1 6.5e-07 29.0 0.1 4.2 4 0 0 4 4 4 3 Cna protein B-type domain CarboxypepD_reg PF13620.1 GAM27430.1 - 7.2e-15 54.8 0.4 0.00023 21.1 0.0 3.8 3 0 0 3 3 3 3 Carboxypeptidase regulatory-like domain CBS PF00571.23 GAM27430.1 - 3e-14 52.5 0.3 2.6e-05 23.8 0.1 3.6 3 0 0 3 3 3 3 CBS domain Y_Y_Y PF07495.8 GAM27430.1 - 0.00069 19.3 0.1 4.3 7.1 0.0 3.5 3 0 0 3 3 3 1 Y_Y_Y domain FlgD_ig PF13860.1 GAM27430.1 - 0.0014 18.2 1.1 16 5.3 0.0 4.7 5 0 0 5 5 5 2 FlgD Ig-like domain DUF2237 PF09996.4 GAM27430.1 - 0.011 15.2 0.0 6.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2237) DUF4019 PF13211.1 GAM27430.1 - 0.056 13.7 0.0 29 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4019) Tyrosinase PF00264.15 GAM27431.1 - 5e-37 128.2 1.0 8.1e-37 127.5 0.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Aldo_ket_red PF00248.16 GAM27432.1 - 4.3e-53 179.9 0.0 5.8e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 GAM27433.1 - 2.8e-51 169.6 14.9 1e-10 41.0 0.0 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM27433.1 - 2.4e-05 22.7 0.7 0.014 13.5 0.2 3.8 1 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM27433.1 - 0.00036 19.3 0.2 0.55 8.9 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 GAM27433.1 - 0.0014 18.3 2.0 0.093 12.4 0.1 2.9 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 GAM27433.1 - 0.01 14.1 0.0 4.2 5.5 0.0 2.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain Cytochrom_C1 PF02167.10 GAM27434.1 - 6.2e-79 264.6 0.0 7.3e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 GAM27434.1 - 0.00022 21.3 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 GAM27434.1 - 0.028 15.2 0.8 0.074 13.8 0.3 1.9 1 1 0 1 1 1 0 Cytochrome c Cpn60_TCP1 PF00118.19 GAM27435.1 - 9e-100 334.5 8.3 1e-99 334.3 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3430 PF11912.3 GAM27437.1 - 7e-14 52.1 19.5 7.8e-14 51.9 13.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Rap_GAP PF02145.10 GAM27438.1 - 2.1e-59 200.0 0.1 3.9e-59 199.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP G-alpha PF00503.15 GAM27439.1 - 2e-108 362.5 8.0 2.2e-108 362.4 5.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 GAM27439.1 - 3.6e-15 55.6 1.4 2.2e-10 40.0 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM27439.1 - 0.00042 19.5 2.5 0.03 13.4 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM27439.1 - 0.0011 18.4 2.1 0.069 12.5 0.1 2.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 GAM27439.1 - 0.0046 17.4 0.3 3.5 8.1 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 GAM27439.1 - 0.053 13.4 0.2 1.6 8.7 0.2 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM27439.1 - 0.086 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Coiled PF05710.7 GAM27441.1 - 0.0061 16.9 11.0 0.012 16.0 7.6 1.5 1 1 0 1 1 1 1 Coiled coil Tox-MPTase3 PF15639.1 GAM27441.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 3 PAT1 PF09770.4 GAM27442.1 - 2.5e-26 92.2 31.2 7.8e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Chromo PF00385.19 GAM27443.1 - 7.7e-13 47.9 3.7 1.6e-12 46.8 2.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PBP1_TM PF14812.1 GAM27443.1 - 0.0087 16.3 30.1 0.26 11.6 4.5 4.9 4 0 0 4 4 4 3 Transmembrane domain of transglycosylase PBP1 at N-terminal Mtf2_C PF14061.1 GAM27443.1 - 0.02 14.7 0.2 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 AT_hook PF02178.14 GAM27443.1 - 0.31 10.8 54.7 0.29 10.9 3.1 6.1 6 0 0 6 6 6 0 AT hook motif Pkinase PF00069.20 GAM27444.1 - 5.2e-67 225.7 0.0 5.2e-67 225.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27444.1 - 5e-50 169.9 0.0 1.2e-49 168.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 GAM27444.1 - 4.3e-14 52.6 0.2 4.3e-14 52.6 0.1 3.4 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 GAM27444.1 - 0.00019 20.4 0.0 0.0039 16.1 0.0 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 GAM27444.1 - 0.96 9.1 8.4 3 7.4 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family GTP_EFTU PF00009.22 GAM27445.1 - 3.1e-60 202.8 0.1 4.5e-60 202.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 GAM27445.1 - 2.1e-32 111.1 0.0 4.6e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 GAM27445.1 - 2.9e-32 110.3 0.0 2.1e-31 107.5 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 GAM27445.1 - 6.1e-25 86.9 0.1 1.4e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 GAM27445.1 - 5.7e-11 42.3 0.0 1.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM27445.1 - 0.0018 18.1 0.1 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF442 PF04273.8 GAM27445.1 - 0.0039 17.0 0.0 8.1 6.3 0.0 3.3 3 0 0 3 3 3 1 Putative phosphatase (DUF442) SUI1 PF01253.17 GAM27445.1 - 0.022 14.5 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor SUI1 FeoB_N PF02421.13 GAM27445.1 - 0.061 12.6 0.3 1.1 8.5 0.0 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.11 GAM27445.1 - 0.073 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 GAM27445.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Peptidase_M66 PF10462.4 GAM27447.1 - 1.5e-58 198.1 0.3 2e-58 197.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM27447.1 - 0.00051 20.5 0.6 0.0014 19.1 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 GAM27447.1 - 0.039 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Matrixin Astacin PF01400.19 GAM27447.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) DUF3827 PF12877.2 GAM27447.1 - 0.22 9.5 1.7 0.31 9.0 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Metallopep PF12044.3 GAM27447.1 - 0.24 9.7 0.3 0.39 9.1 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.4 GAM27448.1 - 3.8e-60 203.3 0.6 5e-60 202.9 0.4 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM27448.1 - 0.069 13.6 0.2 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 GAM27449.1 - 4.9e-62 209.5 0.2 7e-62 209.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Shisa PF13908.1 GAM27449.1 - 0.003 17.7 5.9 0.0067 16.6 4.1 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1510 PF07423.6 GAM27449.1 - 0.011 15.0 0.1 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_M10 PF00413.19 GAM27449.1 - 0.024 14.3 0.1 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin SpoIIIAH PF12685.2 GAM27449.1 - 0.039 13.4 6.4 0.059 12.8 4.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Reprolysin_3 PF13582.1 GAM27449.1 - 0.11 13.0 0.3 0.11 13.0 0.2 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Mucin PF01456.12 GAM27449.1 - 0.24 11.1 32.2 0.58 9.9 22.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_M66 PF10462.4 GAM27450.1 - 6.8e-62 209.0 1.6 8.9e-62 208.6 1.1 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM27450.1 - 0.00097 19.6 0.7 0.0021 18.5 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 GAM27450.1 - 0.066 12.9 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Matrixin Metallopep PF12044.3 GAM27450.1 - 0.26 9.6 0.2 0.45 8.9 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.4 GAM27451.1 - 9.4e-60 202.0 1.4 1.2e-59 201.6 0.9 1.1 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM27451.1 - 0.0088 16.5 0.1 0.024 15.1 0.1 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 GAM27452.1 - 1.4e-60 204.7 1.4 1.8e-60 204.3 1.0 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 GAM27452.1 - 0.027 15.0 0.1 0.064 13.7 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like HEAT_2 PF13646.1 GAM27453.1 - 7.5e-21 74.2 0.0 9.7e-07 28.9 0.0 5.0 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 GAM27453.1 - 1.5e-16 58.8 3.4 0.0024 17.8 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 GAM27453.1 - 1.9e-09 37.7 0.0 0.0029 18.0 0.0 4.8 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 GAM27453.1 - 0.018 14.8 15.2 0.095 12.5 3.1 4.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 GAM27453.1 - 0.029 14.1 0.0 51 3.9 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cpn60_TCP1 PF00118.19 GAM27454.1 - 3.3e-66 223.8 7.1 4e-66 223.6 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L24e PF01246.15 GAM27455.1 - 3.8e-20 71.5 1.2 8.4e-20 70.4 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_S8e PF01201.17 GAM27456.1 - 6.2e-45 152.5 3.7 8.3e-45 152.1 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e HSP90 PF00183.13 GAM27457.1 - 2.1e-159 531.3 14.9 2.9e-159 530.9 10.3 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 GAM27457.1 - 1.8e-11 43.8 2.0 3.3e-11 42.9 0.4 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 GAM27457.1 - 2.6e-07 30.3 0.1 5.6e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Erf4 PF10256.4 GAM27458.1 - 3.5e-26 91.3 0.2 4.4e-26 91.0 0.2 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1084 PF06454.6 GAM27459.1 - 2.5e-11 43.1 7.2 3.4e-11 42.7 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Tic20 PF09685.5 GAM27459.1 - 0.0032 17.4 7.5 0.0032 17.4 5.2 2.2 2 1 0 2 2 2 1 Tic20-like protein Ninjurin PF04923.7 GAM27459.1 - 0.32 10.7 2.4 0.66 9.7 1.7 1.4 1 0 0 1 1 1 0 Ninjurin Peptidase_M50 PF02163.17 GAM27459.1 - 1.3 7.9 5.4 1.7 7.5 2.9 1.8 1 1 1 2 2 2 0 Peptidase family M50 DUF4083 PF13314.1 GAM27459.1 - 3.7 7.4 14.2 0.15 11.8 0.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4083) DUF373 PF04123.8 GAM27459.1 - 7.5 5.4 12.9 13 4.6 9.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) adh_short PF00106.20 GAM27460.1 - 1e-34 119.8 0.0 1.3e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM27460.1 - 9e-18 64.5 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 GAM27460.1 - 3.8e-16 59.6 0.0 4.7e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM27460.1 - 0.0001 21.8 0.1 0.00014 21.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 GAM27460.1 - 0.00028 19.8 1.0 0.00043 19.2 0.7 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 GAM27460.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 GAM27460.1 - 0.0031 17.2 0.2 0.051 13.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 GAM27460.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 GAM27460.1 - 0.0098 15.1 0.1 0.028 13.6 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family PTA_PTB PF01515.14 GAM27460.1 - 0.017 14.1 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase Saccharop_dh PF03435.13 GAM27460.1 - 0.027 13.4 0.1 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Coiled PF05710.7 GAM27461.1 - 1.3e-07 31.9 15.8 1.5e-07 31.7 11.0 1.0 1 0 0 1 1 1 1 Coiled coil RabGAP-TBC PF00566.13 GAM27462.1 - 4.8e-55 186.3 3.6 4.8e-55 186.3 2.5 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain AP_endonuc_2_N PF07582.7 GAM27462.1 - 0.089 12.3 0.0 3.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus Mob_Pre PF01076.14 GAM27462.1 - 0.65 9.5 7.0 0.47 10.0 3.5 1.7 2 0 0 2 2 2 0 Plasmid recombination enzyme Gelsolin PF00626.17 GAM27463.1 - 4.3e-65 215.3 13.7 3.4e-14 52.2 0.0 8.2 8 0 0 8 8 8 7 Gelsolin repeat LRR_4 PF12799.2 GAM27463.1 - 1.8e-27 94.4 49.8 8.8e-07 28.4 5.1 6.9 3 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27463.1 - 2.2e-19 68.9 40.6 1.6e-06 27.7 3.9 5.0 1 1 4 6 6 6 6 Leucine rich repeat VHP PF02209.14 GAM27463.1 - 1.7e-13 50.0 3.6 4.3e-13 48.6 2.5 1.8 1 0 0 1 1 1 1 Villin headpiece domain LRR_1 PF00560.28 GAM27463.1 - 2.6e-11 41.9 35.6 0.17 12.0 0.2 10.3 10 0 0 10 10 10 6 Leucine Rich Repeat LRR_7 PF13504.1 GAM27463.1 - 8.2e-06 25.2 38.8 0.8 10.1 0.5 9.7 9 0 0 9 9 9 5 Leucine rich repeat DUF3244 PF11589.3 GAM27464.1 - 6.6e-23 80.4 0.0 0.012 15.2 0.0 7.2 7 0 0 7 7 7 5 Domain of unknown function (DUF3244) DUF2012 PF09430.5 GAM27464.1 - 4.5e-06 26.4 0.0 0.69 9.7 0.0 6.1 7 0 0 7 7 7 1 Protein of unknown function (DUF2012) DoxA PF07680.6 GAM27464.1 - 0.015 14.9 0.0 1e+02 2.4 0.0 5.4 6 0 0 6 6 6 0 TQO small subunit DoxA TMEM71 PF15121.1 GAM27464.1 - 0.042 13.5 2.6 18 5.0 0.1 3.9 3 0 0 3 3 3 0 TMEM71 protein family HJURP_C PF12347.3 GAM27464.1 - 0.072 12.6 0.0 3.3 7.3 0.0 3.3 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat Dicty_spore_N PF04562.7 GAM27465.1 - 2.7e-23 82.4 26.8 2.7e-23 82.4 18.6 9.5 2 1 9 11 11 11 1 Dictyostelium spore coat protein, N terminus Ank_2 PF12796.2 GAM27466.1 - 0.00011 22.4 0.0 0.00088 19.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM27466.1 - 0.0014 18.6 1.7 0.43 10.9 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.25 GAM27466.1 - 0.0014 18.2 0.1 0.55 10.1 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 GAM27466.1 - 5 7.7 7.2 2.7 8.6 0.0 4.1 5 1 1 6 6 6 0 Ankyrin repeats (many copies) COesterase PF00135.23 GAM27469.1 - 1.2e-116 390.6 0.1 1.5e-116 390.2 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 GAM27469.1 - 6.9e-05 22.5 0.2 0.00028 20.5 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM27469.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Skp1 PF01466.14 GAM27470.1 - 2.9e-11 43.2 0.0 7.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAM27470.1 - 2.7e-05 24.1 0.5 0.077 13.0 0.0 2.7 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain DUF605 PF04652.11 GAM27470.1 - 0.0029 17.0 22.5 0.0029 17.0 15.6 2.3 2 0 0 2 2 2 1 Vta1 like DUF3439 PF11921.3 GAM27470.1 - 9.7 5.9 14.1 1.7 8.3 5.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RNase_PH PF01138.16 GAM27471.1 - 6.6e-33 113.8 0.1 9.1e-33 113.3 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 GAM27471.1 - 5.2e-06 26.3 0.1 3.4e-05 23.7 0.0 2.2 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 PDCD2_C PF04194.8 GAM27472.1 - 7.8e-29 100.3 1.5 1.5e-27 96.1 0.1 4.1 1 1 2 4 4 3 2 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 GAM27472.1 - 0.062 12.7 3.8 12 5.4 0.1 3.8 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 GAM27472.1 - 0.13 12.2 2.7 25 4.9 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Ndc1_Nup PF09531.5 GAM27472.1 - 0.33 9.3 1.5 0.37 9.1 1.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CENP-T PF15511.1 GAM27472.1 - 0.46 9.6 10.7 0.64 9.2 7.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 GAM27472.1 - 0.59 8.5 21.5 0.82 8.0 14.9 1.1 1 0 0 1 1 1 0 Daxx Family TFIIS_C PF01096.13 GAM27472.1 - 0.97 9.1 6.3 16 5.2 0.3 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) SDA1 PF05285.7 GAM27472.1 - 1.6 7.9 23.6 2.2 7.4 16.4 1.2 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 GAM27472.1 - 1.8 8.0 21.3 3 7.4 14.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 GAM27472.1 - 2.2 6.0 21.9 3.1 5.5 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF755 PF05501.6 GAM27472.1 - 7.1 6.7 16.7 0.52 10.3 8.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Ras PF00071.17 GAM27473.1 - 8e-36 122.8 0.0 1.1e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27473.1 - 8.3e-15 55.3 0.0 1.7e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27473.1 - 1e-07 31.3 0.0 1.3e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM27473.1 - 4.9e-05 22.5 0.0 6.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM27473.1 - 8.5e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM27473.1 - 0.0033 16.8 0.0 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 GAM27473.1 - 0.0075 16.6 0.1 1.7 8.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 GAM27473.1 - 0.0079 15.3 0.0 0.065 12.4 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM27473.1 - 0.041 14.1 0.1 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 ABC transporter Memo PF01875.12 GAM27474.1 - 2.4e-83 279.1 0.0 2.8e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein zf-Tim10_DDP PF02953.10 GAM27475.1 - 3.1e-14 51.9 2.7 3.6e-14 51.7 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.4 GAM27475.1 - 0.022 14.5 4.9 0.046 13.5 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF842 PF05811.8 GAM27475.1 - 0.026 14.0 0.8 0.032 13.6 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Pyr_redox_2 PF07992.9 GAM27477.1 - 3.3e-21 76.0 0.0 5.3e-21 75.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM27477.1 - 4e-10 39.9 0.1 1.4e-09 38.1 0.1 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_C PF05199.8 GAM27477.1 - 0.018 15.3 0.2 0.37 11.0 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase Pyr_redox_3 PF13738.1 GAM27477.1 - 0.11 12.5 0.5 20 5.1 0.0 2.8 1 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF4460 PF14687.1 GAM27478.1 - 6.2e-26 90.3 1.7 6.2e-26 90.3 1.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 GAM27478.1 - 3.5e-25 88.9 1.6 6.7e-23 81.4 0.1 3.3 2 2 0 2 2 2 1 Domain of unknown function (DUF4461) DUF4457 PF14652.1 GAM27479.1 - 6.5e-143 475.6 6.7 1.8e-112 375.5 0.8 3.7 3 1 0 3 3 3 3 Domain of unknown function (DUF4457) Mrr_cat PF04471.7 GAM27480.1 - 2.9e-08 33.5 0.0 4.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease GCK PF07802.6 GAM27481.1 - 0.0002 21.4 1.5 0.00026 21.0 1.1 1.2 1 0 0 1 1 1 1 GCK domain CHCH PF06747.8 GAM27481.1 - 0.00069 19.4 3.0 0.0011 18.7 2.1 1.4 1 0 0 1 1 1 1 CHCH domain Pox_F17 PF04767.7 GAM27482.1 - 0.18 12.0 0.8 4 7.7 0.0 2.3 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein SNAPc19 PF15497.1 GAM27482.1 - 0.4 10.9 6.7 0.18 12.0 0.3 2.6 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Kelch_3 PF13415.1 GAM27483.1 - 1.2e-26 92.1 0.0 1.8e-08 34.3 0.0 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM27483.1 - 3.7e-26 90.5 0.7 1.9e-08 34.0 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 GAM27483.1 - 1.2e-23 82.4 0.8 2.7e-08 33.2 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 GAM27483.1 - 1e-20 72.9 6.1 1.6e-06 28.0 0.1 5.1 2 1 3 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM27483.1 - 1.5e-19 69.4 1.0 2.2e-05 24.1 0.0 5.2 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM27483.1 - 3.8e-15 54.9 4.6 0.00012 21.6 0.0 5.1 5 0 0 5 5 5 3 Kelch motif bZIP_1 PF00170.16 GAM27484.1 - 1.6e-13 50.3 10.3 3.9e-13 49.1 7.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM27484.1 - 5.5e-07 29.3 12.8 1.7e-06 27.7 6.1 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 GAM27484.1 - 0.00029 21.0 5.0 0.00066 19.9 3.5 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor CASP_C PF08172.7 GAM27484.1 - 0.008 15.2 1.0 0.008 15.2 0.7 2.0 2 1 0 2 2 2 1 CASP C terminal DUF972 PF06156.8 GAM27484.1 - 0.017 15.4 0.4 0.06 13.6 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 GAM27484.1 - 0.2 11.7 7.5 0.59 10.2 5.2 1.7 1 0 0 1 1 1 0 Cortexillin I, coiled coil Tyrosinase PF00264.15 GAM27484.1 - 1.3 9.0 6.6 1.4 8.9 0.5 2.2 1 1 1 2 2 2 0 Common central domain of tyrosinase IncA PF04156.9 GAM27484.1 - 1.9 8.0 8.2 0.18 11.3 2.4 1.7 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 GAM27485.1 - 3.5e-52 172.5 16.3 3.7e-11 42.4 0.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 GAM27485.1 - 4.3e-06 26.5 3.4 0.03 14.0 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 GAM27485.1 - 0.00098 17.3 1.9 0.14 10.3 0.3 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 GAM27485.1 - 0.016 14.2 1.4 1.7 7.6 0.0 3.3 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 GAM27485.1 - 0.057 11.6 0.1 0.23 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PD40 PF07676.7 GAM27485.1 - 0.099 12.3 3.7 54 3.5 0.2 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Pribosyltran PF00156.22 GAM27486.1 - 1.9e-13 50.2 0.0 6.8e-13 48.4 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 GAM27486.1 - 1.7e-06 27.4 0.0 2.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_28 PF13521.1 GAM27487.1 - 2.7e-29 102.2 0.0 3.9e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Bromodomain PF00439.20 GAM27488.1 - 7.3e-20 70.6 0.1 2.2e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Kelch_3 PF13415.1 GAM27489.1 - 5.3e-44 147.4 3.8 1.3e-13 50.6 0.0 6.8 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM27489.1 - 5.1e-42 141.4 1.1 1e-11 44.4 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM27489.1 - 4e-31 106.3 1.4 6.8e-08 31.9 0.0 5.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM27489.1 - 7.2e-31 104.7 7.2 3e-08 33.0 0.1 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 GAM27489.1 - 4.2e-29 99.4 1.8 6.2e-07 29.3 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 GAM27489.1 - 6.7e-29 99.3 0.1 1.2e-05 25.1 0.0 5.3 5 0 0 5 5 5 5 Kelch motif RAG2 PF03089.9 GAM27489.1 - 0.045 12.4 1.5 1.9 7.1 0.0 3.5 3 1 2 5 5 5 0 Recombination activating protein 2 TrmE_N PF10396.4 GAM27491.1 - 6e-25 87.4 0.0 1.4e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 GAM27491.1 - 2e-19 69.7 1.1 8e-19 67.8 0.1 2.5 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 GAM27491.1 - 2.8e-19 69.1 0.0 6.5e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM27491.1 - 7.7e-09 35.5 1.1 3.4e-05 23.7 0.0 2.6 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 GAM27491.1 - 2e-06 27.1 0.0 5.7e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 GAM27491.1 - 2.7e-05 23.6 0.0 0.0044 16.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 GAM27491.1 - 0.00017 22.3 0.1 0.0012 19.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 GAM27491.1 - 0.0019 18.6 0.0 0.0059 17.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 GAM27491.1 - 0.0025 18.1 2.7 0.031 14.5 1.9 2.3 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 GAM27491.1 - 0.0031 17.4 0.0 0.0083 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 GAM27491.1 - 0.0031 16.9 0.1 0.36 10.2 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 GAM27491.1 - 0.0048 17.2 0.5 0.1 12.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain Guanylate_kin PF00625.16 GAM27491.1 - 0.0052 16.2 0.1 0.033 13.6 0.0 2.2 2 0 0 2 2 2 1 Guanylate kinase AAA_16 PF13191.1 GAM27491.1 - 0.008 16.1 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 GAM27491.1 - 0.014 14.5 0.0 0.043 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ArgK PF03308.11 GAM27491.1 - 0.017 13.8 1.0 2.7 6.7 0.2 2.9 1 1 1 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 GAM27491.1 - 0.031 13.8 0.1 1.8 8.0 0.0 3.2 3 1 1 4 4 4 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 GAM27491.1 - 0.042 13.9 0.1 0.27 11.4 0.0 2.5 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.1 GAM27491.1 - 0.064 12.6 0.0 0.29 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF362 PF04015.7 GAM27491.1 - 0.078 12.4 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF362) HSP70 PF00012.15 GAM27492.1 - 3.8e-272 903.6 12.3 4.3e-272 903.4 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM27492.1 - 1.7e-15 56.4 0.4 3.7e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 GAM27492.1 - 0.00052 18.9 0.3 0.0055 15.5 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 GAM27492.1 - 0.00075 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 GAM27492.1 - 0.004 16.2 0.2 0.026 13.6 0.0 2.3 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase AAA_2 PF07724.9 GAM27493.1 - 3.4e-05 23.8 0.0 7.9e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 GAM27493.1 - 0.00094 19.3 1.8 0.0074 16.4 0.4 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 GAM27493.1 - 0.0086 15.8 0.1 0.094 12.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 GAM27493.1 - 0.017 15.3 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lipoprotein_1 PF00820.14 GAM27493.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein HSP20 PF00011.16 GAM27494.1 - 5.6e-20 71.1 0.0 6.5e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HNH_5 PF14279.1 GAM27494.1 - 0.1 12.5 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease GTP_EFTU PF00009.22 GAM27495.1 - 8.3e-46 155.7 0.2 1.3e-45 155.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 GAM27495.1 - 4.3e-20 71.7 0.4 4.3e-20 71.7 0.2 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 GAM27495.1 - 3.1e-06 27.2 0.5 1.2e-05 25.3 0.4 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM27495.1 - 2.1e-05 24.4 0.0 0.0001 22.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM27495.1 - 0.0032 16.2 0.1 0.007 15.0 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 GAM27495.1 - 0.11 12.9 3.1 0.82 10.1 0.0 3.3 3 1 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 GAM27495.1 - 0.12 11.8 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Neisseria_TspB PF05616.8 GAM27495.1 - 8.2 4.6 8.4 14 3.9 5.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Fumble PF03630.9 GAM27496.1 - 3.7e-123 410.7 1.8 4.3e-123 410.5 1.2 1.0 1 0 0 1 1 1 1 Fumble Lipase_3 PF01764.20 GAM27497.1 - 3.7e-30 104.3 0.0 4.5e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 GAM27497.1 - 0.00098 18.8 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM27497.1 - 0.004 17.0 0.1 0.0042 16.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 GAM27497.1 - 0.015 14.5 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 GAM27497.1 - 0.015 14.6 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 GAM27497.1 - 0.022 14.3 0.8 0.055 13.0 0.3 1.5 1 1 0 2 2 2 0 PGAP1-like protein Cutinase PF01083.17 GAM27497.1 - 0.18 11.5 0.9 0.31 10.7 0.6 1.4 1 1 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 GAM27498.1 - 9e-32 109.6 0.0 1.3e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2013 PF09431.5 GAM27500.1 - 3.6e-17 62.4 1.3 5.7e-17 61.7 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Spindle_Spc25 PF08234.7 GAM27500.1 - 0.041 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 DUF2373 PF10180.4 GAM27501.1 - 5.6e-19 67.4 0.5 5.6e-19 67.4 0.3 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) JmjC PF02373.17 GAM27502.1 - 7.7e-13 48.6 0.0 7.7e-13 48.6 0.0 3.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase PWWP PF00855.12 GAM27502.1 - 0.0015 18.7 0.0 0.0047 17.1 0.0 1.9 1 0 0 1 1 1 1 PWWP domain GPI PF06560.6 GAM27502.1 - 0.0076 15.2 0.7 0.017 14.1 0.1 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.6 GAM27502.1 - 0.066 12.7 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Cupin domain E2F_TDP PF02319.15 GAM27503.1 - 6.1e-19 67.3 0.3 2.8e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 GAM27503.1 - 0.11 12.2 0.4 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF4573 PF15140.1 GAM27504.1 - 1.4e-12 47.5 15.7 4.6e-07 29.5 6.0 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) PRKCSH_1 PF13015.1 GAM27504.1 - 9.6e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PLDc_2 PF13091.1 GAM27505.1 - 2.4e-12 46.7 0.0 5.7e-05 22.8 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM27505.1 - 0.029 14.1 2.2 0.03 14.1 0.3 2.1 2 0 0 2 2 2 0 Phospholipase D Active site motif Med30 PF11315.3 GAM27505.1 - 0.12 12.5 0.2 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 CBS PF00571.23 GAM27507.1 - 3.9e-28 96.9 5.0 5.7e-07 29.2 0.0 4.2 4 0 0 4 4 4 4 CBS domain RBD PF02196.10 GAM27507.1 - 0.036 13.8 0.1 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 Raf-like Ras-binding domain F-box PF00646.28 GAM27508.1 - 0.0001 21.8 1.0 0.00028 20.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 GAM27508.1 - 0.0034 17.0 1.9 0.011 15.4 0.4 2.2 2 0 0 2 2 2 1 F-box-like tRNA_bind_2 PF13725.1 GAM27508.1 - 0.046 13.8 0.5 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 Possible tRNA binding domain Sdh_cyt PF01127.17 GAM27509.1 - 1.8e-21 76.1 2.2 2.8e-21 75.5 1.5 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Voltage_CLC PF00654.15 GAM27511.1 - 1.6e-96 323.4 17.1 1.6e-96 323.4 11.9 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 GAM27511.1 - 7.9e-14 51.1 0.9 1.4e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 CBS domain HEAT PF02985.17 GAM27512.1 - 0.36 11.0 8.6 5.4 7.3 0.0 5.8 7 0 0 7 7 7 0 HEAT repeat DcpS_C PF11969.3 GAM27513.1 - 5.9e-27 94.1 2.0 1.1e-26 93.2 1.4 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 GAM27513.1 - 2.1e-15 57.0 0.5 4.6e-15 55.9 0.3 1.6 1 0 0 1 1 1 1 HIT domain zf-C2H2 PF00096.21 GAM27513.1 - 0.066 13.5 0.7 0.2 12.0 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM27513.1 - 0.091 13.1 0.4 0.091 13.1 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger FRG2 PF15315.1 GAM27514.1 - 0.31 10.9 4.4 0.54 10.2 3.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 LRR_4 PF12799.2 GAM27515.1 - 2.8e-07 30.0 1.8 5.9e-05 22.5 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM27515.1 - 0.00019 21.1 3.1 4 7.8 0.0 4.3 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.1 GAM27515.1 - 0.0007 19.3 8.7 0.0018 18.0 0.2 4.3 5 1 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 GAM27515.1 - 0.0025 17.5 2.1 6.7 7.1 0.0 4.6 3 0 0 3 3 3 1 Leucine Rich Repeat Histone PF00125.19 GAM27516.1 - 2e-32 111.1 0.9 3.2e-32 110.4 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM27516.1 - 0.00011 22.3 0.1 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 GAM27516.1 - 0.0087 15.3 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 GAM27516.1 - 0.088 12.8 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 GAM27516.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SET PF00856.23 GAM27517.1 - 9.6e-27 94.2 0.1 9.6e-27 94.2 0.1 4.3 2 2 0 2 2 2 1 SET domain Cnd1 PF12717.2 GAM27519.1 - 2e-05 24.4 4.5 6.5e-05 22.8 0.7 2.7 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 GAM27519.1 - 8.7e-05 22.2 6.6 18 5.7 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM27519.1 - 0.0092 16.3 0.7 8.8 6.7 0.0 3.3 1 1 3 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 GAM27519.1 - 0.019 15.2 1.4 1.2 9.4 0.4 3.2 1 1 2 3 3 3 0 HEAT repeats RIX1 PF08167.7 GAM27519.1 - 1.1 8.9 10.2 0.15 11.7 1.3 2.8 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis PX PF00787.19 GAM27521.1 - 1.1e-10 41.3 0.2 1.1e-10 41.3 0.2 2.7 3 0 0 3 3 3 1 PX domain Dynamin_N PF00350.18 GAM27521.1 - 2.3e-06 27.5 0.2 2.3e-06 27.5 0.1 3.9 3 3 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 GAM27521.1 - 7.4e-05 22.6 0.5 7.4e-05 22.6 0.3 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 GAM27521.1 - 0.1 13.1 0.1 0.1 13.1 0.0 3.1 2 1 1 3 3 3 0 Miro-like protein DUF4611 PF15387.1 GAM27521.1 - 0.55 10.4 17.3 2.3 8.4 5.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Kelch_4 PF13418.1 GAM27522.1 - 7.3e-42 140.9 16.5 4.4e-09 35.9 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM27522.1 - 4e-41 138.2 19.5 2.3e-09 37.1 0.5 7.8 7 0 0 7 7 7 4 Galactose oxidase, central domain RasGEF PF00617.14 GAM27522.1 - 2.7e-38 131.5 1.0 5.7e-38 130.5 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain Kelch_1 PF01344.20 GAM27522.1 - 9.3e-36 121.1 8.2 3.5e-09 36.0 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM27522.1 - 3.9e-31 105.9 14.4 1.5e-06 28.1 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 GAM27522.1 - 1.5e-29 101.4 14.4 1.4e-07 31.3 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM27522.1 - 2.6e-22 77.6 8.0 1.5e-05 24.5 0.1 6.6 6 0 0 6 6 6 4 Kelch motif RasGEF_N PF00618.15 GAM27522.1 - 5.7e-22 77.7 0.3 5.7e-22 77.7 0.2 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif DUF4131 PF13567.1 GAM27523.1 - 0.095 12.1 1.2 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3463 PF11946.3 GAM27524.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) DUF1191 PF06697.7 GAM27524.1 - 0.029 13.2 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) NCU-G1 PF15065.1 GAM27524.1 - 0.072 11.7 0.0 0.79 8.3 0.0 2.0 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 EphA2_TM PF14575.1 GAM27524.1 - 0.18 12.2 0.4 0.36 11.2 0.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TPK_catalytic PF04263.11 GAM27525.1 - 8.3e-27 93.2 0.0 1.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 GAM27525.1 - 4.1e-14 52.0 0.1 8.3e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CMAS PF02353.15 GAM27526.1 - 9e-87 290.6 0.0 1.1e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 GAM27526.1 - 3.3e-12 46.9 0.0 6.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM27526.1 - 8.1e-11 41.8 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM27526.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM27526.1 - 8.6e-09 35.7 0.0 2.6e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM27526.1 - 1e-06 29.1 0.0 2.7e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 GAM27526.1 - 2.6e-05 23.6 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 GAM27526.1 - 3e-05 23.1 0.0 5.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 GAM27526.1 - 0.00029 20.8 0.0 0.00071 19.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM27526.1 - 0.0038 16.6 0.0 0.0074 15.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 GAM27526.1 - 0.0041 17.9 0.0 0.014 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 GAM27526.1 - 0.007 15.6 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.15 GAM27526.1 - 0.015 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 GAM27526.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.7 GAM27526.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase NAD_binding_8 PF13450.1 GAM27527.1 - 2.1e-17 62.9 0.2 4.8e-17 61.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 GAM27527.1 - 1.5e-13 50.6 0.1 5e-12 45.6 0.0 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 GAM27527.1 - 3.1e-09 36.2 0.1 8.1e-09 34.8 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM27527.1 - 3.6e-07 29.4 1.9 5.1e-07 28.8 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 GAM27527.1 - 5.3e-05 22.4 0.8 8.5e-05 21.7 0.5 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 GAM27527.1 - 6.3e-05 23.2 0.6 0.00017 21.8 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM27527.1 - 8.3e-05 22.7 0.3 0.0011 19.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM27527.1 - 0.00038 19.0 0.7 0.00079 18.0 0.5 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 GAM27527.1 - 0.00039 19.6 0.6 0.00066 18.8 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 GAM27527.1 - 0.00054 19.7 0.3 0.78 9.4 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 GAM27527.1 - 0.001 18.0 1.6 0.0019 17.1 1.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 GAM27527.1 - 0.0012 18.8 0.4 0.0022 17.9 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM27527.1 - 0.0025 16.9 1.1 0.013 14.5 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 GAM27527.1 - 0.0033 17.0 1.1 0.0056 16.3 0.8 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 GAM27527.1 - 0.014 14.8 0.9 0.027 13.9 0.4 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAM27527.1 - 0.014 15.0 0.2 0.024 14.3 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 GAM27527.1 - 0.023 14.0 0.7 0.04 13.3 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.14 GAM27527.1 - 0.03 12.5 0.0 0.044 11.9 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like LRR_1 PF00560.28 GAM27528.1 - 8.5e-05 22.0 12.0 1.2 9.4 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.2 GAM27528.1 - 0.00016 21.1 0.5 0.00016 21.1 0.3 5.0 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27528.1 - 0.00019 21.0 12.0 0.00036 20.2 1.4 3.6 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 GAM27528.1 - 0.00033 20.4 9.0 2.3 8.5 0.1 5.8 5 0 0 5 5 5 2 Leucine Rich repeat Bac_rhamnosid_N PF08531.5 GAM27528.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain DUF4099 PF13351.1 GAM27528.1 - 0.098 12.5 0.1 0.36 10.7 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4099) LRR_6 PF13516.1 GAM27530.1 - 0.0011 18.7 1.0 0.0011 18.7 0.7 4.0 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.1 GAM27530.1 - 0.78 9.5 4.7 2.9 7.7 2.6 2.5 1 1 2 3 3 3 0 Leucine rich repeat PX PF00787.19 GAM27532.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 PX domain PH PF00169.24 GAM27533.1 - 9.9e-15 54.6 4.9 1.7e-14 53.9 0.1 2.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM27533.1 - 1.8e-06 28.1 4.6 9.8e-06 25.7 0.1 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM27533.1 - 1.2e-05 25.3 0.1 3.3e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 GAM27533.1 - 5.1e-05 23.2 0.0 0.00017 21.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 GAM27533.1 - 0.00044 20.1 0.0 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 GAM27533.1 - 0.039 14.1 0.1 0.56 10.3 0.0 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain SepZ PF06066.6 GAM27533.1 - 0.083 12.8 0.0 0.083 12.8 0.0 2.6 3 0 0 3 3 3 0 SepZ Phytoreo_P8 PF07124.6 GAM27533.1 - 6.3 5.3 9.1 3 6.3 4.0 1.8 2 0 0 2 2 2 0 Phytoreovirus outer capsid protein P8 Transketolase_N PF00456.16 GAM27534.1 - 6.6e-107 357.1 0.2 1.1e-106 356.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 GAM27534.1 - 2.6e-43 147.5 0.0 6.3e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 GAM27534.1 - 1.9e-11 43.9 0.0 5e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 GAM27534.1 - 1.2e-07 30.9 0.1 1.4e-05 24.1 0.0 2.7 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 GAM27534.1 - 0.00035 20.1 0.1 0.0042 16.6 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ras PF00071.17 GAM27535.1 - 1.2e-41 141.7 0.0 1.5e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27535.1 - 2e-16 60.5 0.0 3.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27535.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM27535.1 - 1.1e-06 27.9 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 GAM27535.1 - 0.0021 17.3 0.0 0.01 15.0 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM27535.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM27535.1 - 0.016 14.6 0.1 0.075 12.4 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TerD PF02342.13 GAM27536.1 - 1.4e-55 187.5 0.0 1.8e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 TerD domain TIG PF01833.19 GAM27537.1 - 1.1e-22 79.7 52.1 2.1e-08 34.0 1.0 8.1 8 0 0 8 8 8 5 IPT/TIG domain Lectin_C PF00059.16 GAM27537.1 - 2.4e-08 34.5 0.3 2.7e-07 31.1 0.1 2.4 2 0 0 2 2 2 1 Lectin C-type domain EGF_2 PF07974.8 GAM27537.1 - 0.0014 18.7 10.1 0.0052 16.9 7.0 2.0 1 0 0 1 1 1 1 EGF-like domain DUF1049 PF06305.6 GAM27537.1 - 0.018 14.5 0.2 0.036 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) EGF PF00008.22 GAM27537.1 - 0.096 12.6 6.4 0.44 10.5 4.5 2.2 1 0 0 1 1 1 0 EGF-like domain GST_C_3 PF14497.1 GAM27538.1 - 0.22 12.0 0.7 16 6.0 0.0 3.7 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF3184 PF11380.3 GAM27539.1 - 9.4e-08 30.4 3.0 3.1e-05 22.1 1.5 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3184) DUF4548 PF15081.1 GAM27539.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4548) Metallophos PF00149.23 GAM27540.1 - 1.8e-17 63.4 1.7 3.4e-17 62.5 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_1 PF05184.10 GAM27540.1 - 0.0014 18.4 0.3 0.0051 16.6 0.2 2.0 1 0 0 1 1 1 1 Saposin-like type B, region 1 SapB_2 PF03489.12 GAM27540.1 - 0.019 14.9 2.0 0.66 10.0 0.0 3.6 3 0 0 3 3 3 0 Saposin-like type B, region 2 Peptidase_S8 PF00082.17 GAM27541.1 - 2.4e-40 138.4 1.9 4.5e-40 137.5 1.3 1.4 1 0 0 1 1 1 1 Subtilase family HrpE PF06188.7 GAM27542.1 - 0.0098 15.6 2.2 0.015 15.0 1.5 1.2 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E cNMP_binding PF00027.24 GAM27543.1 - 2.9e-49 164.8 0.0 6e-24 83.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 GAM27543.1 - 0.032 13.7 0.1 0.082 12.4 0.1 1.7 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.7 GAM27543.1 - 0.065 12.6 0.3 0.24 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) ThiS PF02597.15 GAM27544.1 - 2.2e-12 47.2 0.0 3.8e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 ThiS family DUF1077 PF06417.7 GAM27545.1 - 4.4e-36 123.0 4.0 5.4e-36 122.7 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) YadA_stalk PF05662.9 GAM27545.1 - 1.1 9.1 5.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin zf-RING_2 PF13639.1 GAM27546.1 - 2.8e-14 52.6 7.6 2.8e-14 52.6 5.3 2.1 2 0 0 2 2 2 1 Ring finger domain CUE PF02845.11 GAM27546.1 - 5.6e-11 41.7 0.0 1.4e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 CUE domain zf-C3HC4_3 PF13920.1 GAM27546.1 - 8.6e-09 34.9 4.2 1.5e-08 34.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM27546.1 - 1.8e-08 34.3 8.6 1.8e-08 34.3 6.0 2.8 3 1 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM27546.1 - 3.2e-08 33.4 7.3 6.8e-08 32.4 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM27546.1 - 9.9e-08 31.5 7.2 9.9e-08 31.5 5.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM27546.1 - 3.3e-06 26.7 6.2 3.3e-06 26.7 4.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM27546.1 - 3.1e-05 23.5 6.8 0.00011 21.8 4.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAM27546.1 - 0.00061 19.6 4.8 0.0014 18.4 3.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 GAM27546.1 - 0.0037 17.0 5.9 0.0037 17.0 4.1 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 GAM27546.1 - 0.046 13.7 8.1 0.1 12.6 5.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 GAM27546.1 - 0.19 11.6 5.5 0.55 10.2 3.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 GAM27546.1 - 0.25 10.9 4.6 0.52 9.9 3.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RNA_pol_Rpb2_6 PF00562.23 GAM27547.1 - 8.2e-116 386.9 0.0 1.3e-115 386.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAM27547.1 - 1.4e-52 177.5 1.6 1.6e-52 177.4 0.5 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 GAM27547.1 - 1.2e-28 99.1 0.1 2.8e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 GAM27547.1 - 5.3e-24 84.6 0.8 1.6e-23 83.1 0.8 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 GAM27547.1 - 1.8e-21 75.6 0.2 6e-21 74.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 GAM27547.1 - 5.5e-21 74.0 0.0 1.3e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 GAM27547.1 - 5.4e-10 39.0 0.2 3.4e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Cpn60_TCP1 PF00118.19 GAM27548.1 - 2.1e-89 300.3 0.2 2.8e-89 299.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family 2OG-FeII_Oxy PF03171.15 GAM27549.1 - 3.1e-16 59.4 0.1 5.4e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 GAM27549.1 - 2e-12 47.6 0.7 1.5e-11 44.8 0.5 2.3 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Cupin_2 PF07883.6 GAM27550.1 - 1.8e-11 43.3 0.2 1.8e-11 43.3 0.2 1.5 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 GAM27550.1 - 1.6e-05 24.3 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 GAM27550.1 - 8.8e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain FdtA PF05523.6 GAM27550.1 - 0.016 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.6 GAM27550.1 - 0.02 13.8 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) JmjC PF02373.17 GAM27550.1 - 0.1 12.8 0.2 0.25 11.6 0.2 1.9 1 1 0 1 1 1 0 JmjC domain, hydroxylase Esterase_phd PF10503.4 GAM27552.1 - 0.00021 20.5 0.1 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 GAM27552.1 - 0.0015 18.2 0.3 0.0041 16.8 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM27552.1 - 0.016 15.1 0.2 0.019 14.8 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 GAM27553.1 - 1.6e-64 217.5 0.0 5e-64 215.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27553.1 - 3.1e-31 108.3 0.0 8.4e-31 106.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27553.1 - 3.8e-10 39.1 0.0 1.5e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAM27553.1 - 4e-05 23.0 0.1 0.0001 21.7 0.1 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 GAM27553.1 - 0.0026 17.1 0.0 0.0074 15.6 0.0 1.8 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 GAM27553.1 - 0.0027 16.8 0.0 0.0065 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM27553.1 - 0.071 12.8 0.3 2.2 7.9 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DivIC PF04977.10 GAM27553.1 - 0.47 9.9 11.7 1.3 8.5 1.2 2.6 2 0 0 2 2 2 0 Septum formation initiator Choline_kinase PF01633.15 GAM27553.1 - 1.1 8.7 6.6 1.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Choline/ethanolamine kinase IncA PF04156.9 GAM27553.1 - 4.6 6.7 18.4 28 4.2 0.3 3.3 2 1 0 2 2 2 0 IncA protein CutC PF03932.9 GAM27554.1 - 2.2e-45 154.4 0.0 2.7e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 CutC family FAD_binding_3 PF01494.14 GAM27555.1 - 4.5e-20 72.0 0.0 5.8e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 GAM27555.1 - 1.2e-10 40.9 0.0 0.0001 21.3 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM27555.1 - 5.7e-10 38.4 0.0 1.9e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 GAM27555.1 - 9.4e-06 25.9 0.0 0.00027 21.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM27555.1 - 1.7e-05 24.0 0.1 8.2e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 GAM27555.1 - 4.3e-05 23.4 0.1 0.00012 22.0 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 GAM27555.1 - 0.00038 19.4 0.0 0.21 10.4 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_oxidored PF12831.2 GAM27555.1 - 0.006 15.7 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM27555.1 - 0.0082 14.6 0.0 0.015 13.7 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 GAM27555.1 - 0.0088 15.4 0.0 0.27 10.6 0.0 2.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 GAM27555.1 - 0.015 14.1 0.0 0.035 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 GAM27555.1 - 0.015 15.3 0.0 0.05 13.6 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 GAM27555.1 - 0.041 13.7 0.0 0.18 11.6 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Med3 PF11593.3 GAM27556.1 - 0.61 9.2 5.4 0.66 9.1 3.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Myb_DNA-binding PF00249.26 GAM27557.1 - 2.4e-11 43.4 0.0 4.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1202 PF06717.6 GAM27557.1 - 0.016 14.5 0.8 0.027 13.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) UVR PF02151.14 GAM27558.1 - 0.011 15.2 0.2 0.011 15.2 0.2 3.5 3 0 0 3 3 3 0 UvrB/uvrC motif Alpha_kinase PF02816.13 GAM27559.1 - 1.8e-57 194.0 0.1 2.5e-57 193.5 0.1 1.2 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 GAM27559.1 - 6e-32 108.3 7.7 7.6e-07 28.7 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 GAM27559.1 - 3e-07 28.9 1.9 0.0043 15.2 0.1 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 GAM27559.1 - 0.00011 21.0 1.6 0.099 11.3 0.6 3.1 1 1 2 3 3 3 3 Nup133 N terminal like TFIIA PF03153.8 GAM27559.1 - 0.87 9.4 25.9 1.3 8.7 17.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Polysacc_deac_1 PF01522.16 GAM27560.1 - 1.3e-21 76.5 0.1 6.9e-20 70.9 0.1 2.3 1 1 1 2 2 2 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 GAM27560.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase PBP1_TM PF14812.1 GAM27560.1 - 0.49 10.7 2.9 0.61 10.4 0.0 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.4 GAM27560.1 - 0.99 8.8 16.5 1.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ketoacyl-synt PF00109.21 GAM27561.1 - 1.3e-78 264.0 1.1 1.9e-76 256.8 0.0 3.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 GAM27561.1 - 1.3e-63 215.2 0.0 2.7e-63 214.2 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 GAM27561.1 - 5.2e-41 140.7 0.0 8.3e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 GAM27561.1 - 1.4e-40 138.9 0.1 4.5e-40 137.2 0.0 2.0 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 GAM27561.1 - 1.3e-34 119.5 0.2 5.1e-34 117.5 0.1 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 GAM27561.1 - 3.8e-34 117.0 0.4 1.5e-32 111.9 0.0 2.9 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_C PF02797.10 GAM27561.1 - 1.6e-25 89.7 0.1 4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ADH_zinc_N PF00107.21 GAM27561.1 - 1.2e-22 79.7 0.1 6e-22 77.5 0.1 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Chal_sti_synt_N PF00195.14 GAM27561.1 - 3.6e-20 72.2 0.2 7.6e-20 71.1 0.2 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.7 GAM27561.1 - 8.8e-15 54.5 0.5 8.8e-15 54.5 0.3 2.5 3 0 0 3 3 3 1 FAE1/Type III polyketide synthase-like protein ADH_zinc_N_2 PF13602.1 GAM27561.1 - 2.7e-09 37.9 0.0 1.5e-08 35.5 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 GAM27561.1 - 3e-09 36.9 0.2 7.3e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 GAM27561.1 - 9.8e-09 34.9 0.2 3.1e-08 33.3 0.1 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 GAM27561.1 - 2.6e-08 33.7 0.4 0.00021 21.2 0.0 4.1 4 0 0 4 4 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.18 GAM27561.1 - 2.1e-06 26.9 0.0 8.9e-06 24.8 0.0 2.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 GAM27561.1 - 0.00023 20.7 6.0 0.0049 16.4 0.6 3.4 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HEAT_2 PF13646.1 GAM27563.1 - 2.9e-05 24.2 0.1 6.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 HEAT repeats UME PF08064.8 GAM27563.1 - 0.0025 17.7 0.9 0.0051 16.7 0.7 1.4 1 0 0 1 1 1 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 GAM27563.1 - 0.016 15.6 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT PF02985.17 GAM27563.1 - 0.073 13.1 5.9 0.23 11.6 0.0 3.6 5 0 0 5 5 5 0 HEAT repeat DUF2435 PF10363.4 GAM27563.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 GAM27563.1 - 0.2 12.2 0.7 1.2 9.6 0.0 2.5 2 1 0 2 2 2 0 HEAT-like repeat RIX1 PF08167.7 GAM27563.1 - 0.21 11.2 4.8 0.69 9.5 0.8 2.5 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis DEAD PF00270.24 GAM27564.1 - 2e-40 138.0 0.2 4.3e-40 136.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM27564.1 - 2.5e-23 81.7 1.7 1.5e-13 50.3 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 GAM27564.1 - 6.9e-06 26.0 0.0 6.9e-06 26.0 0.0 4.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit MAGSP PF03082.9 GAM27565.1 - 0.0038 16.6 0.1 0.0048 16.3 0.1 1.1 1 0 0 1 1 1 1 Male accessory gland secretory protein DUF1664 PF07889.7 GAM27566.1 - 0.041 13.6 0.9 0.28 11.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 GAM27566.1 - 0.044 13.6 5.8 0.093 12.5 1.0 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1395 PF07160.7 GAM27566.1 - 0.053 13.0 0.7 0.53 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DUF2203 PF09969.4 GAM27566.1 - 0.081 13.1 0.2 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1098 PF06497.6 GAM27566.1 - 0.086 12.9 0.5 0.76 9.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1098) Syntaxin PF00804.20 GAM27566.1 - 0.34 11.1 3.6 1.7 8.8 2.1 2.4 1 1 1 2 2 2 0 Syntaxin DUF1748 PF08520.5 GAM27567.1 - 5.4e-08 32.3 0.0 6.9e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MRP-L20 PF12824.2 GAM27568.1 - 2.8e-05 24.1 2.7 2.8e-05 24.1 1.9 2.5 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_38 PF13936.1 GAM27568.1 - 0.00043 19.7 0.2 0.00091 18.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Neugrin PF06413.6 GAM27568.1 - 0.049 13.4 6.0 0.28 10.9 4.2 2.3 1 1 0 1 1 1 0 Neugrin LAG1-DNAbind PF09271.6 GAM27568.1 - 3 8.3 10.3 16 5.9 0.1 2.9 2 1 0 3 3 3 0 LAG1, DNA binding Myb_DNA-binding PF00249.26 GAM27569.1 - 1.2e-11 44.4 0.1 9.7e-08 31.9 0.0 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM27569.1 - 0.00093 19.2 3.0 0.63 10.1 0.0 3.3 3 1 0 3 3 3 2 Myb-like DNA-binding domain Peptidase_M20 PF01546.23 GAM27570.1 - 4e-34 117.7 0.0 5.4e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM27570.1 - 8.2e-14 51.3 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 GAM27570.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 YEATS PF03366.11 GAM27571.1 - 2.8e-26 91.0 0.1 8.8e-26 89.4 0.0 1.8 2 0 0 2 2 2 1 YEATS family Curto_V2 PF07325.6 GAM27571.1 - 3.9 7.1 5.9 5.7 6.6 1.3 2.2 1 1 1 2 2 2 0 Curtovirus V2 protein DUF4337 PF14235.1 GAM27571.1 - 6.9 6.4 9.8 14 5.5 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Chitin_bind_3 PF03067.10 GAM27572.1 - 1.3e-34 120.1 1.0 1.5e-34 119.9 0.7 1.0 1 0 0 1 1 1 1 Chitin binding domain Methyltransf_2 PF00891.13 GAM27573.1 - 5.5e-32 110.8 0.2 1.4e-30 106.3 0.0 2.0 1 1 1 2 2 2 1 O-methyltransferase Methyltransf_31 PF13847.1 GAM27573.1 - 1.7e-06 27.7 0.1 4e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM27573.1 - 7e-05 23.3 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM27573.1 - 7e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 GAM27573.1 - 0.00034 20.9 0.0 0.0019 18.4 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAM27573.1 - 0.00086 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 GAM27573.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 GAM27573.1 - 0.013 15.9 0.0 0.066 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain SgrR_N PF12793.2 GAM27573.1 - 0.066 13.2 0.1 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term Sulfolobus_pRN PF05584.6 GAM27573.1 - 0.068 13.1 0.4 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein LRR_6 PF13516.1 GAM27574.1 - 4.3e-40 131.2 45.4 0.00058 19.6 0.1 14.5 14 0 0 14 14 14 12 Leucine Rich repeat LRR_1 PF00560.28 GAM27574.1 - 2.6e-08 32.7 14.2 9.4 6.7 0.0 11.1 11 1 0 11 11 11 1 Leucine Rich Repeat LRR_4 PF12799.2 GAM27574.1 - 6.5e-08 32.0 31.9 0.24 11.0 0.7 8.6 2 2 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27574.1 - 2.7e-05 23.8 26.5 0.025 14.3 1.7 7.5 2 2 5 7 7 7 4 Leucine rich repeat Carb_bind PF10645.4 GAM27574.1 - 0.024 14.4 1.6 0.064 13.0 0.1 2.3 2 0 0 2 2 2 0 Carbohydrate binding Cut8_N PF14482.1 GAM27574.1 - 0.49 10.4 5.5 1.7 8.7 3.8 1.9 1 1 0 1 1 1 0 Cut8 proteasome-binding domain FliE PF02049.13 GAM27575.1 - 0.17 11.9 4.6 0.65 10.0 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE Zip PF02535.17 GAM27575.1 - 7.1 5.5 23.2 0.65 8.9 11.7 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter zf-DHHC PF01529.15 GAM27576.1 - 6.8e-19 67.9 11.2 6.8e-19 67.9 7.7 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase DNA_pol_B PF00136.16 GAM27577.1 - 1.2e-117 393.5 0.5 1.2e-117 393.5 0.4 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 GAM27577.1 - 3.7e-31 108.2 0.1 9.3e-31 106.8 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 GAM27577.1 - 2.4e-23 82.5 3.3 2.4e-23 82.5 2.3 2.1 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger AAA_21 PF13304.1 GAM27577.1 - 0.0019 18.2 0.2 0.0019 18.2 0.1 2.9 3 0 0 3 3 3 1 AAA domain Rhomboid PF01694.17 GAM27578.1 - 2.5e-39 134.6 14.9 5.3e-39 133.5 10.3 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 GAM27578.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.4 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) Ribosomal_L6 PF00347.18 GAM27579.1 - 4.2e-26 91.2 6.1 7.1e-16 58.4 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Na_H_Exchanger PF00999.16 GAM27580.1 - 7.5e-69 232.0 46.3 1.1e-68 231.4 32.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ADK PF00406.17 GAM27581.1 - 1.7e-47 161.0 0.0 2.2e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 GAM27581.1 - 2.2e-12 46.4 0.0 8.7e-12 44.5 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 GAM27581.1 - 7.7e-10 38.8 0.0 1.3e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM27581.1 - 1e-07 32.8 0.1 1.6e-07 32.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM27581.1 - 1.6e-07 31.7 0.2 3.8e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 GAM27581.1 - 4.3e-05 22.9 1.6 0.42 9.9 0.0 3.2 2 1 0 3 3 3 2 Thymidylate kinase Zeta_toxin PF06414.7 GAM27581.1 - 0.0062 15.6 0.7 0.056 12.5 0.2 2.1 2 0 0 2 2 2 1 Zeta toxin 6PF2K PF01591.13 GAM27581.1 - 0.12 11.4 1.0 1.5 7.8 0.0 2.7 2 1 1 3 3 3 0 6-phosphofructo-2-kinase dNK PF01712.14 GAM27581.1 - 0.22 11.4 1.6 0.24 11.2 0.1 1.8 2 1 0 2 2 2 0 Deoxynucleoside kinase Mito_carr PF00153.22 GAM27582.1 - 8.5e-52 172.8 6.8 3.9e-21 74.5 0.5 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 GAM27582.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif TPT PF03151.11 GAM27583.1 - 3.1e-08 33.3 15.2 3.1e-08 33.3 10.5 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 GAM27583.1 - 0.00014 20.9 25.4 0.00037 19.5 17.6 1.7 1 1 0 1 1 1 1 UAA transporter family Pox_I5 PF04713.7 GAM27583.1 - 6.6 6.5 14.5 0.054 13.2 1.7 3.2 3 1 0 3 3 3 0 Poxvirus protein I5 SH2 PF00017.19 GAM27584.1 - 2.7e-11 43.1 0.0 8.2e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain RNA_pol_Rpb4 PF03874.11 GAM27584.1 - 0.0038 17.2 3.2 0.0038 17.2 2.2 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb4 Cbl_N3 PF02762.9 GAM27584.1 - 0.033 13.8 0.0 0.39 10.3 0.0 2.7 2 1 1 3 3 3 0 CBL proto-oncogene N-terminus, SH2-like domain Dict-STAT-coil PF09267.5 GAM27584.1 - 0.052 13.7 0.3 0.052 13.7 0.2 4.0 3 1 1 4 4 4 0 Dictyostelium STAT, coiled coil GATA PF00320.22 GAM27585.1 - 1.7e-16 59.2 5.5 5e-16 57.7 3.8 1.9 1 0 0 1 1 1 1 GATA zinc finger DUF2406 PF10295.4 GAM27585.1 - 0.057 13.9 1.1 0.057 13.9 0.7 2.6 3 0 0 3 3 3 0 Uncharacterised protein (DUF2406) DZR PF12773.2 GAM27585.1 - 0.63 9.9 5.4 0.074 12.8 0.4 2.0 2 0 0 2 2 2 0 Double zinc ribbon GFA PF04828.9 GAM27585.1 - 8.4 6.4 10.6 5.9 6.9 0.0 3.0 3 1 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme PPP4R2 PF09184.6 GAM27586.1 - 0.02 14.4 15.9 0.01 15.4 9.3 1.7 1 1 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 GAM27586.1 - 0.027 12.5 7.5 0.039 11.9 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3870 PF12986.2 GAM27586.1 - 0.074 13.3 1.6 0.19 12.0 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) PBP1_TM PF14812.1 GAM27586.1 - 1.1 9.5 14.9 5.3 7.4 10.4 2.2 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Astro_capsid PF03115.9 GAM27586.1 - 2.7 6.1 10.9 3.7 5.6 7.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF948 PF06103.6 GAM27586.1 - 2.9 7.8 7.8 0.89 9.4 1.4 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cwf_Cwc_15 PF04889.7 GAM27586.1 - 4.1 7.0 17.4 0.17 11.5 7.9 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 GAM27586.1 - 5.3 6.8 16.6 0.47 10.3 8.1 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myb_DNA-bind_6 PF13921.1 GAM27587.1 - 1e-28 99.1 6.8 4.9e-14 52.1 0.2 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 GAM27587.1 - 2e-28 98.1 12.1 5.2e-15 55.2 1.3 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 GAM27587.1 - 0.0007 19.6 15.5 0.0059 16.7 1.6 3.6 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 GAM27587.1 - 0.059 13.2 11.3 1.4 8.8 0.9 4.4 3 3 1 4 4 4 0 Myb/SANT-like DNA-binding domain Pex14_N PF04695.8 GAM27587.1 - 0.2 11.7 2.2 0.6 10.1 0.0 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MADF_DNA_bdg PF10545.4 GAM27587.1 - 2.2 8.5 12.2 7.8 6.7 0.9 3.7 2 2 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Nbl1_Borealin_N PF10444.4 GAM27588.1 - 1.1e-12 47.1 0.2 1.9e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal MAD PF05557.8 GAM27589.1 - 1.1e-53 182.4 73.2 5.2e-33 114.1 1.0 2.4 1 1 1 2 2 2 2 Mitotic checkpoint protein DUF4145 PF13643.1 GAM27589.1 - 1.2 9.0 7.5 0.71 9.7 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) PG_binding_4 PF12229.3 GAM27590.1 - 0.00042 20.5 0.2 0.00093 19.4 0.1 1.6 1 1 0 1 1 1 1 Putative peptidoglycan binding domain MHC_I PF00129.13 GAM27590.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Orbi_NS1 PF01718.11 GAM27590.1 - 0.037 12.0 0.3 0.041 11.9 0.2 1.0 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein DUF935 PF06074.7 GAM27590.1 - 0.044 12.5 0.3 0.06 12.0 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF935) SR-25 PF10500.4 GAM27591.1 - 0.01 15.3 18.6 0.013 15.0 12.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NifQ PF04891.7 GAM27591.1 - 0.45 10.6 7.5 0.54 10.3 5.2 1.2 1 0 0 1 1 1 0 NifQ bZIP_C PF12498.3 GAM27591.1 - 1.6 10.0 18.9 2.7 9.2 13.1 1.6 1 1 0 1 1 1 0 Basic leucine-zipper C terminal Membralin PF09746.4 GAM27591.1 - 1.9 7.4 6.8 2 7.3 4.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein RR_TM4-6 PF06459.7 GAM27591.1 - 2 8.2 12.1 2.1 8.1 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tub PF01167.13 GAM27591.1 - 3.9 6.3 12.8 3.5 6.5 8.2 1.4 1 1 0 1 1 1 0 Tub family Ofd1_CTDD PF10637.4 GAM27591.1 - 4.1 6.4 10.3 4.5 6.3 7.2 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DivIC PF04977.10 GAM27591.1 - 4.8 6.7 13.1 13 5.3 9.1 1.8 1 0 0 1 1 1 0 Septum formation initiator TraV PF09676.5 GAM27591.1 - 5.8 7.6 14.2 5.3 7.7 9.2 1.5 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF853 PF05872.7 GAM27591.1 - 6.2 5.0 11.5 6.1 5.0 7.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) VIT1 PF01988.14 GAM27591.1 - 6.2 6.2 7.1 7.6 5.9 4.9 1.1 1 0 0 1 1 1 0 VIT family CDC45 PF02724.9 GAM27591.1 - 7 4.5 16.5 8.6 4.2 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 GAM27594.1 - 4.5e-14 51.8 0.0 1.4e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27594.1 - 1.8e-08 34.2 0.0 0.00049 20.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27594.1 - 5e-08 32.6 0.0 3.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 GAM27594.1 - 0.00044 19.8 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 DbpA RNA binding domain NHL PF01436.16 GAM27595.1 - 7.4e-06 25.6 5.0 0.001 18.9 0.5 4.3 4 0 0 4 4 4 2 NHL repeat Reg_prop PF07494.6 GAM27595.1 - 0.055 13.5 0.6 0.61 10.2 0.3 3.0 3 0 0 3 3 3 0 Two component regulator propeller FH2 PF02181.18 GAM27596.1 - 6.1e-84 282.0 2.5 6.1e-84 282.0 1.7 3.3 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 GAM27596.1 - 3.1e-35 121.3 0.8 3.1e-35 121.3 0.5 4.2 4 1 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 GAM27596.1 - 1.7e-34 118.8 3.9 1.7e-34 118.8 2.7 3.0 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain C2 PF00168.25 GAM27596.1 - 3.9e-16 58.6 0.4 1e-15 57.3 0.3 1.8 1 0 0 1 1 1 1 C2 domain DUF1664 PF07889.7 GAM27596.1 - 8.2 6.2 12.4 10 5.9 3.9 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Glucosamine_iso PF01182.15 GAM27597.1 - 7.8e-38 130.1 0.0 9e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Skp1 PF01466.14 GAM27598.1 - 2.6e-30 104.2 0.2 5.3e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAM27598.1 - 3.1e-18 65.6 0.1 6.3e-18 64.6 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PYST-C1 PF09690.5 GAM27598.1 - 0.014 14.9 0.3 0.033 13.8 0.2 1.6 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Rab5ip PF07019.7 GAM27599.1 - 1.2e-16 60.5 8.3 1.9e-16 59.9 5.7 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) BTP PF05232.7 GAM27599.1 - 0.85 9.4 6.8 0.2 11.4 0.5 2.3 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family DUF3810 PF12725.2 GAM27599.1 - 7.8 5.2 9.5 3 6.6 4.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) SNF2_N PF00176.18 GAM27600.1 - 6.5e-76 254.9 1.5 1.6e-75 253.6 1.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 GAM27600.1 - 6.6e-14 51.4 0.4 6.6e-14 51.4 0.3 3.5 2 1 0 2 2 2 1 HSA Helicase_C PF00271.26 GAM27600.1 - 4e-13 49.0 0.0 1.4e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 GAM27600.1 - 0.00018 21.4 0.0 0.00058 19.8 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM27600.1 - 0.0002 21.3 0.2 0.00098 19.1 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Presenilin PF01080.12 GAM27601.1 - 1.1e-96 324.1 11.0 1.1e-96 324.1 7.6 1.7 1 1 1 2 2 2 1 Presenilin DUF4519 PF15012.1 GAM27601.1 - 9.2 6.2 6.0 2.4 8.1 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) PhyH PF05721.8 GAM27602.1 - 3.4e-16 59.9 0.1 4.6e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 GAM27602.1 - 0.031 14.5 0.1 0.085 13.1 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase CarboxypepD_reg PF13620.1 GAM27603.1 - 2e-25 88.6 9.9 0.0088 16.0 0.0 10.5 10 1 0 10 10 10 7 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 GAM27603.1 - 2.9e-23 81.3 19.5 0.0015 18.2 0.3 12.1 12 1 0 12 12 12 7 Cna protein B-type domain DUF2012 PF09430.5 GAM27603.1 - 6.4e-10 38.9 0.0 0.69 9.7 0.0 7.5 8 0 0 8 8 8 2 Protein of unknown function (DUF2012) FlgD_ig PF13860.1 GAM27603.1 - 0.00035 20.2 8.0 3.5 7.4 0.0 7.6 8 1 1 9 9 9 2 FlgD Ig-like domain fn3_3 PF14686.1 GAM27603.1 - 0.0021 18.1 5.5 4.5 7.4 0.0 5.7 6 0 0 6 6 6 1 Polysaccharide lyase family 4, domain II SNF2_N PF00176.18 GAM27604.1 - 6.7e-70 235.2 0.0 1.3e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM27604.1 - 3.8e-15 55.5 0.0 1.4e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2824 PF11039.3 GAM27604.1 - 0.0038 16.9 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2824) Rep_fac_C PF08542.6 GAM27604.1 - 0.063 13.2 1.0 13 5.7 0.0 3.1 2 0 0 2 2 2 0 Replication factor C C-terminal domain Myb_DNA-bind_6 PF13921.1 GAM27605.1 - 0.00033 20.7 0.3 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2 PF00096.21 GAM27605.1 - 1.9 9.0 5.3 0.78 10.2 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type JAB PF01398.16 GAM27607.1 - 3.8e-31 107.1 0.1 7.1e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAM27607.1 - 1.5e-06 27.6 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 GAM27607.1 - 0.0021 17.5 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Glyco_transf_22 PF03901.12 GAM27608.1 - 1.6e-65 221.7 27.5 2.1e-65 221.3 19.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3353 PF11833.3 GAM27608.1 - 0.018 14.5 0.6 0.018 14.5 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3353) Pex14_N PF04695.8 GAM27608.1 - 1.7 8.6 8.0 1.7 8.6 2.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Response_reg PF00072.19 GAM27609.1 - 2.2e-20 72.7 0.9 5.7e-20 71.4 0.6 1.7 1 0 0 1 1 1 1 Response regulator receiver domain LRR_6 PF13516.1 GAM27609.1 - 1.9e-14 52.0 39.4 0.13 12.4 0.0 11.2 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 GAM27609.1 - 1.8e-08 33.8 43.7 0.039 13.5 0.0 8.1 4 3 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27609.1 - 8.3e-08 31.8 32.7 0.0098 15.6 3.7 5.7 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 GAM27609.1 - 6.3e-05 22.4 33.9 4 7.8 0.1 10.4 8 3 2 10 10 10 2 Leucine Rich Repeat TFIIA PF03153.8 GAM27609.1 - 0.0026 17.7 19.7 0.0026 17.7 13.6 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF3247 PF11607.3 GAM27609.1 - 0.044 14.0 1.5 4.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3247) Peptidase_S64 PF08192.6 GAM27609.1 - 0.83 7.9 18.5 0.71 8.1 11.8 1.6 2 0 0 2 2 2 0 Peptidase family S64 Dicty_REP PF05086.7 GAM27609.1 - 1.2 6.7 18.3 2.3 5.8 12.7 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LRR_7 PF13504.1 GAM27609.1 - 1.3 9.4 33.0 5.5 7.6 0.1 10.0 8 2 0 8 8 8 0 Leucine rich repeat RR_TM4-6 PF06459.7 GAM27609.1 - 6.3 6.6 14.0 12 5.6 9.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cpn60_TCP1 PF00118.19 GAM27610.1 - 1.9e-139 465.3 13.5 2.2e-139 465.1 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Lipase_3 PF01764.20 GAM27611.1 - 1e-18 67.3 0.0 2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ank_2 PF12796.2 GAM27613.1 - 5.3e-15 55.5 7.4 0.0004 20.6 0.0 8.7 4 3 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM27613.1 - 0.00043 20.7 7.4 0.44 11.1 0.1 7.1 9 0 0 9 9 9 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM27613.1 - 0.00066 19.8 0.5 15 6.0 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27613.1 - 0.00082 19.3 15.8 41 4.8 0.0 11.1 14 0 0 14 14 14 0 Ankyrin repeat Ank PF00023.25 GAM27613.1 - 0.022 14.5 10.2 14 5.6 0.0 8.2 9 0 0 9 9 9 0 Ankyrin repeat Aldolase_2 PF10120.4 GAM27613.1 - 0.068 12.5 0.1 0.47 9.8 0.0 2.4 3 0 0 3 3 3 0 Putative aldolase Sigma70_ner PF04546.8 GAM27613.1 - 0.24 10.9 2.9 0.35 10.4 0.5 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region FNIP PF05725.7 GAM27616.1 - 0.037 13.9 6.1 9.1 6.3 0.4 4.4 3 1 0 3 3 3 0 FNIP Repeat LRR_8 PF13855.1 GAM27616.1 - 0.23 11.2 8.9 0.15 11.8 1.2 3.4 3 1 0 3 3 3 0 Leucine rich repeat Pkinase PF00069.20 GAM27617.1 - 3.2e-44 151.0 0.0 3.8e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27617.1 - 3.3e-21 75.5 0.0 4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27617.1 - 1.5e-05 24.1 0.0 8e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 GAM27617.1 - 2.3e-05 24.2 0.0 0.0024 17.6 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 GAM27617.1 - 0.031 13.6 0.1 0.55 9.5 0.1 2.1 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 GAM27617.1 - 0.037 13.5 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SRP40_C PF05022.7 GAM27620.1 - 7.5e-15 55.1 1.5 7.5e-15 55.1 1.0 3.3 4 0 0 4 4 4 1 SRP40, C-terminal domain LisH PF08513.6 GAM27620.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 LisH MIP-T3 PF10243.4 GAM27620.1 - 0.13 10.6 68.6 0.21 10.0 47.6 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pentapeptide PF00805.17 GAM27621.1 - 3.5e-42 141.0 40.3 6.5e-14 50.7 4.6 4.6 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 GAM27621.1 - 9.6e-25 86.1 11.3 3e-14 52.5 1.3 2.6 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 GAM27621.1 - 2e-21 75.6 8.7 6.1e-07 29.2 0.1 4.9 2 2 2 4 4 4 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 GAM27621.1 - 5.5e-17 61.7 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3354 PF11834.3 GAM27621.1 - 1.5e-14 53.3 0.0 2.9e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3354) BTB PF00651.26 GAM27621.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_8 PF13450.1 GAM27621.1 - 0.0073 16.3 0.1 3.5 7.7 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DCX PF03607.12 GAM27621.1 - 0.0093 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Doublecortin Acyltransferase PF01553.16 GAM27622.1 - 3.9e-19 68.3 0.0 6e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.8 GAM27622.1 - 0.069 11.8 0.0 0.18 10.4 0.0 1.7 1 1 0 1 1 1 0 Diacylglycerol acyltransferase TPR_19 PF14559.1 GAM27623.1 - 2.2e-11 43.9 28.4 0.0018 18.5 0.4 8.0 5 3 2 8 8 8 5 Tetratricopeptide repeat SRP72 PF08492.7 GAM27623.1 - 1.1e-09 38.5 9.7 1.1e-09 38.5 6.7 3.2 3 0 0 3 3 3 1 SRP72 RNA-binding domain TPR_11 PF13414.1 GAM27623.1 - 1.2e-09 37.6 28.7 0.025 14.1 0.1 7.1 6 2 1 7 7 7 5 TPR repeat TPR_14 PF13428.1 GAM27623.1 - 3.4e-09 36.5 1.1 17 6.3 0.0 7.9 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM27623.1 - 1.5e-08 33.9 28.8 0.2 11.6 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM27623.1 - 1.5e-08 35.0 7.9 8.3 7.2 0.0 8.4 8 2 1 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM27623.1 - 1.5e-07 30.6 27.5 0.093 12.3 0.1 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM27623.1 - 4e-06 26.8 49.6 0.0022 18.0 7.4 6.9 2 2 6 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 GAM27623.1 - 4.2e-06 26.1 13.4 2.4 8.1 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM27623.1 - 1.7e-05 24.9 16.3 0.24 11.9 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM27623.1 - 0.00014 21.7 25.7 0.29 11.0 0.2 7.7 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 GAM27623.1 - 0.0027 17.5 0.1 19 5.1 0.0 4.5 5 2 1 6 6 5 0 Tetratricopeptide repeat PPR PF01535.15 GAM27623.1 - 0.039 13.9 4.0 1.2e+02 3.0 0.0 6.3 8 0 0 8 8 8 0 PPR repeat TPR_17 PF13431.1 GAM27623.1 - 2.5 8.5 16.4 12 6.4 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat HCaRG PF07258.9 GAM27624.1 - 1.4e-13 50.7 0.3 1.6e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 HCaRG protein A_thal_3526 PF09713.5 GAM27625.1 - 1.2e-18 66.9 2.2 2e-18 66.2 1.5 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) IBN_N PF03810.14 GAM27625.1 - 0.017 14.9 0.2 0.048 13.5 0.1 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain TMEM151 PF14857.1 GAM27625.1 - 1.3 7.5 5.8 1.9 7.0 3.1 1.9 1 1 0 1 1 1 0 TMEM151 family DNA_alkylation PF08713.6 GAM27626.1 - 1.7e-56 191.0 0.3 2.6e-56 190.5 0.2 1.2 1 0 0 1 1 1 1 DNA alkylation repair enzyme MRI PF15325.1 GAM27626.1 - 0.091 13.7 8.9 0.24 12.3 6.1 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection SOBP PF15279.1 GAM27626.1 - 0.33 11.2 4.9 0.43 10.8 3.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TPPII_N PF12583.3 GAM27626.1 - 3.2 7.8 11.6 4.9 7.2 8.1 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal SR-25 PF10500.4 GAM27626.1 - 8.8 5.7 18.2 17 4.8 12.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Voltage_CLC PF00654.15 GAM27628.1 - 5.6e-91 305.2 24.9 5.6e-91 305.2 17.2 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAM27628.1 - 1.6e-14 53.4 0.5 6.5e-07 29.0 0.0 3.3 2 1 0 2 2 2 2 CBS domain TAT_signal PF10518.4 GAM27628.1 - 0.074 13.0 0.2 0.074 13.0 0.2 3.1 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.4 GAM27628.1 - 0.085 12.0 0.2 0.29 10.3 0.1 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2418 PF10332.4 GAM27628.1 - 0.45 10.8 0.0 0.45 10.8 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2418) PKD_channel PF08016.7 GAM27629.1 - 3.9e-34 117.8 21.4 3.1e-19 68.7 11.0 2.5 1 1 1 2 2 2 2 Polycystin cation channel GST_C PF00043.20 GAM27629.1 - 0.021 14.8 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FUSC PF04632.7 GAM27629.1 - 0.037 12.4 10.8 0.055 11.8 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PAH PF02671.16 GAM27629.1 - 0.22 11.1 2.2 0.27 10.8 0.1 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat Menin PF05053.8 GAM27629.1 - 0.27 9.3 4.4 0.38 8.8 3.1 1.1 1 0 0 1 1 1 0 Menin LON PF02190.11 GAM27629.1 - 0.28 10.8 7.4 0.21 11.2 2.4 2.6 2 1 0 2 2 2 0 ATP-dependent protease La (LON) domain VPS9 PF02204.13 GAM27630.1 - 5.8e-26 90.5 5.3 6.1e-26 90.4 0.9 3.3 5 0 0 5 5 5 1 Vacuolar sorting protein 9 (VPS9) domain Ribosomal_S15 PF00312.17 GAM27631.1 - 2.6e-18 65.5 3.4 6.4e-18 64.2 2.4 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 Ribophorin_II PF05817.9 GAM27632.1 - 1.1e-63 215.4 6.7 1.4e-63 215.1 4.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF1667 PF07892.6 GAM27632.1 - 0.028 14.1 0.2 0.068 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) HA2 PF04408.18 GAM27633.1 - 6.2e-23 80.7 1.0 3.5e-22 78.3 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 GAM27633.1 - 1.9e-18 66.3 0.0 5.4e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 GAM27633.1 - 4e-11 42.6 0.1 1.4e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM27633.1 - 1.6e-07 30.9 0.0 5.2e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM27633.1 - 0.00027 21.0 0.0 0.00076 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain WD40 PF00400.27 GAM27634.1 - 1.4e-30 104.0 1.2 2.2e-07 30.5 0.0 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 GAM27634.1 - 0.0014 16.8 0.1 0.0029 15.8 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 GAM27634.1 - 0.0049 15.1 0.0 0.032 12.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 GAM27634.1 - 0.0063 16.0 0.0 0.3 10.4 0.0 2.8 2 1 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.6 GAM27634.1 - 0.043 12.5 0.4 2.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like DUF4282 PF14110.1 GAM27635.1 - 5.1e-10 39.4 10.2 6e-10 39.1 7.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) DUF2975 PF11188.3 GAM27635.1 - 0.54 9.9 7.3 0.77 9.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) ZZ PF00569.12 GAM27636.1 - 1.2e-09 37.5 16.8 1.2e-06 27.9 3.0 3.7 3 1 0 3 3 3 2 Zinc finger, ZZ type MCPVI PF02993.9 GAM27636.1 - 1.2 9.2 7.3 2.2 8.3 5.0 1.4 1 0 0 1 1 1 0 Minor capsid protein VI SRP_SPB PF02978.14 GAM27638.1 - 4e-10 39.8 0.0 1.2e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Signal peptide binding domain NUDE_C PF04880.8 GAM27639.1 - 4.3e-07 30.4 13.0 4.3e-07 30.4 9.0 3.6 1 1 2 3 3 2 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 GAM27639.1 - 1.3e-05 23.8 26.4 2.3e-05 23.0 18.3 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF904 PF06005.7 GAM27639.1 - 0.0013 18.9 3.0 0.0013 18.9 2.1 4.2 3 2 1 4 4 4 1 Protein of unknown function (DUF904) BicD PF09730.4 GAM27639.1 - 0.014 13.8 24.8 0.023 13.0 17.2 1.4 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Baculo_PEP_C PF04513.7 GAM27639.1 - 0.046 13.5 6.8 1 9.1 0.4 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.4 GAM27639.1 - 0.085 11.5 24.4 0.31 9.7 17.0 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 GAM27639.1 - 0.13 11.9 29.3 0.48 10.1 4.0 3.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TMCO5 PF14992.1 GAM27639.1 - 0.25 10.4 26.8 0.35 9.9 9.7 2.4 1 1 1 2 2 2 0 TMCO5 family ERM PF00769.14 GAM27639.1 - 0.32 10.4 36.5 0.012 15.1 19.6 2.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Zein-binding PF04576.10 GAM27639.1 - 0.35 11.0 23.8 0.03 14.4 7.5 3.0 1 1 1 2 2 2 0 Zein-binding ALMT PF11744.3 GAM27639.1 - 0.36 9.4 10.5 0.53 8.8 7.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Fib_alpha PF08702.5 GAM27639.1 - 0.56 10.3 22.3 3.1 7.8 8.3 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Halo_GVPC PF05465.8 GAM27639.1 - 0.73 9.8 3.5 5 7.1 0.1 2.9 3 0 0 3 3 2 0 Halobacterial gas vesicle protein C (GVPC) repeat IncA PF04156.9 GAM27639.1 - 0.82 9.2 36.1 5.1 6.6 13.6 3.2 1 1 2 3 3 3 0 IncA protein Laminin_II PF06009.7 GAM27639.1 - 0.96 9.2 16.6 2.1 8.0 7.5 2.8 2 1 1 3 3 2 0 Laminin Domain II DUF972 PF06156.8 GAM27639.1 - 1.3 9.3 24.9 1.6 9.0 2.3 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 GAM27639.1 - 1.3 7.8 17.7 0.095 11.6 7.3 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) APG6 PF04111.7 GAM27639.1 - 1.4 7.9 30.9 5.1 6.0 8.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Rab5-bind PF09311.6 GAM27639.1 - 1.6 8.6 32.4 0.046 13.6 11.8 3.0 1 1 1 2 2 2 0 Rabaptin-like protein GAS PF13851.1 GAM27639.1 - 1.6 7.8 30.8 1.5 7.9 18.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 GAM27639.1 - 5.1 4.2 27.8 11 3.2 19.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin PF00804.20 GAM27639.1 - 5.5 7.2 26.0 0.028 14.5 9.0 2.8 2 1 1 3 3 2 0 Syntaxin Mnd1 PF03962.10 GAM27639.1 - 6.4 6.3 28.2 23 4.5 9.1 2.4 1 1 1 2 2 2 0 Mnd1 family BRE1 PF08647.6 GAM27639.1 - 8.1 6.4 26.9 0.44 10.5 1.7 4.2 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DSX_dimer PF08828.5 GAM27640.1 - 0.073 12.6 0.2 0.095 12.2 0.2 1.4 1 1 0 1 1 1 0 Doublesex dimerisation domain AAA PF00004.24 GAM27641.1 - 1.3e-38 132.1 0.0 7.5e-38 129.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 GAM27641.1 - 6e-08 32.4 0.6 1.8e-07 30.9 0.4 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.5 GAM27641.1 - 1.6e-07 31.0 0.0 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 GAM27641.1 - 3.1e-05 23.1 0.0 0.00012 21.1 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM27641.1 - 3.6e-05 23.9 0.1 0.0028 17.8 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 GAM27641.1 - 0.00035 20.5 0.0 0.001 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAM27641.1 - 0.00086 19.0 0.2 0.01 15.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 GAM27641.1 - 0.0015 17.3 0.0 0.0026 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Bac_DnaA PF00308.13 GAM27641.1 - 0.0016 18.1 0.1 0.023 14.3 0.0 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.1 GAM27641.1 - 0.0036 17.2 0.0 0.02 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM27641.1 - 0.0043 17.8 0.0 0.022 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF4368 PF14287.1 GAM27641.1 - 0.007 16.1 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4368) Mg_chelatase PF01078.16 GAM27641.1 - 0.0076 15.4 0.1 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 GAM27641.1 - 0.0082 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Guanylate_kin PF00625.16 GAM27641.1 - 0.013 15.0 0.1 0.31 10.4 0.0 2.6 2 1 1 3 3 3 0 Guanylate kinase AAA_19 PF13245.1 GAM27641.1 - 0.017 14.8 0.1 0.064 13.0 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Cna_B PF05738.8 GAM27642.1 - 2.7e-31 107.1 28.5 1.2e-05 24.9 0.0 13.2 12 1 0 12 12 12 8 Cna protein B-type domain DUF2012 PF09430.5 GAM27642.1 - 1.6e-11 44.1 0.0 1.3 8.8 0.0 8.7 9 0 0 9 9 9 3 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 GAM27642.1 - 2.4e-07 30.7 0.2 9e-05 22.4 0.1 16.2 11 1 2 13 13 13 7 Carboxypeptidase regulatory-like domain Terpene_synth_C PF03936.11 GAM27642.1 - 1.6 7.8 2.5 40 3.3 0.0 3.4 4 0 0 4 4 4 0 Terpene synthase family, metal binding domain Mito_carr PF00153.22 GAM27643.1 - 3.2e-58 193.4 3.7 2.1e-18 65.7 0.0 4.2 3 2 1 4 4 4 3 Mitochondrial carrier protein CDK2AP PF09806.4 GAM27643.1 - 0.0015 18.7 3.1 0.0028 17.9 2.2 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 GAM27643.1 - 0.027 13.3 11.1 0.041 12.7 7.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2062 PF09835.4 GAM27643.1 - 0.047 13.3 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) UPF0560 PF10577.4 GAM27643.1 - 0.88 7.7 8.6 1.2 7.2 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1741 PF08427.5 GAM27644.1 - 4.4e-62 209.6 1.4 1.1e-61 208.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) PRP21_like_P PF12230.3 GAM27644.1 - 0.0056 16.2 5.4 0.01 15.3 3.7 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Bundlin PF05307.6 GAM27644.1 - 0.065 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Bundlin Cbl_N PF02262.11 GAM27644.1 - 0.13 11.9 3.8 7.3 6.3 0.1 3.0 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 Suf PF05843.9 GAM27644.1 - 0.33 10.6 7.3 0.7 9.5 5.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ank_2 PF12796.2 GAM27645.1 - 2.9e-11 43.5 0.1 3.1e-05 24.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM27645.1 - 3.8e-08 33.6 0.2 0.017 15.6 0.0 5.2 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27645.1 - 3.7e-06 26.6 0.3 2.2 8.7 0.0 6.0 6 1 1 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 GAM27645.1 - 3.2e-05 24.0 0.0 1.3 9.3 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) DUF3447 PF11929.3 GAM27645.1 - 0.0028 17.4 0.4 0.65 9.8 0.0 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) Ank PF00023.25 GAM27645.1 - 0.038 13.8 0.0 25 4.9 0.0 3.9 3 0 0 3 3 3 0 Ankyrin repeat AAA_22 PF13401.1 GAM27647.1 - 0.0011 19.1 0.1 0.0044 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM27647.1 - 0.01 16.6 0.0 0.062 14.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 GAM27647.1 - 0.079 12.5 0.0 1.4 8.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain FNIP PF05725.7 GAM27648.1 - 9.1e-91 297.6 42.0 9.2e-16 57.5 0.4 8.6 7 1 0 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 GAM27648.1 - 7.1e-07 29.0 9.3 0.52 10.2 0.0 6.6 4 2 4 9 9 9 3 Protein of unknown function (DUF1769) CH PF00307.26 GAM27649.1 - 3.6e-32 110.6 7.9 5.8e-08 32.7 0.0 5.5 3 1 1 5 5 5 5 Calponin homology (CH) domain PH PF00169.24 GAM27649.1 - 1e-07 32.1 0.4 4.8e-07 29.9 0.3 2.1 1 1 0 1 1 1 1 PH domain CAMSAP_CH PF11971.3 GAM27649.1 - 1.6e-07 30.8 0.1 0.013 15.1 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain FERM_N PF09379.5 GAM27649.1 - 9.3e-05 22.4 0.0 0.9 9.6 0.0 2.9 2 0 0 2 2 2 2 FERM N-terminal domain V_ATPase_I PF01496.14 GAM27649.1 - 0.25 9.1 6.2 0.41 8.4 4.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_transf_5 PF08323.6 GAM27650.1 - 2.1e-34 119.1 0.0 4e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 GAM27650.1 - 8.2e-15 54.6 0.0 6.6e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 GAM27650.1 - 4.2e-07 29.6 0.0 9.6e-06 25.2 0.0 2.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.1 GAM27650.1 - 0.00084 19.4 0.0 0.0024 18.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 GAM27650.1 - 0.046 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 GAM27650.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Notch PF00066.12 GAM27651.1 - 1.5e-68 226.7 133.9 1.5e-10 41.1 8.6 8.9 9 0 0 9 9 9 8 LNR domain Adap_comp_sub PF00928.16 GAM27654.1 - 3.1e-93 311.6 0.1 3.9e-93 311.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM27654.1 - 2.2e-10 40.4 0.5 3.7e-10 39.6 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DDHD PF02862.12 GAM27655.1 - 2.2e-34 119.2 0.1 4.3e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.9 GAM27655.1 - 0.14 11.4 0.0 0.97 8.6 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) WD40 PF00400.27 GAM27656.1 - 3.5e-47 156.6 28.3 1.2e-09 37.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat HhH-GPD PF00730.20 GAM27657.1 - 1.5e-20 73.4 0.0 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 GAM27657.1 - 0.00018 20.9 0.0 0.00074 19.0 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 GAM27657.1 - 0.016 15.3 5.4 0.029 14.5 3.8 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III PBP1_TM PF14812.1 GAM27657.1 - 0.29 11.4 14.1 0.22 11.8 6.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_1 PF00076.17 GAM27658.1 - 1.2e-19 69.6 0.1 1.7e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27658.1 - 2.9e-14 52.7 0.0 4.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27658.1 - 1.2e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 GAM27658.1 - 0.054 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Sod_Fe_C PF02777.13 GAM27659.1 - 2.4e-26 91.6 0.6 4.1e-26 90.8 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 GAM27659.1 - 1.8e-10 40.9 0.1 1.8e-10 40.9 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PsiB PF06290.6 GAM27659.1 - 0.034 13.5 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) EMP70 PF02990.11 GAM27660.1 - 9.7e-162 539.0 18.4 9.7e-162 539.0 12.8 1.9 3 0 0 3 3 3 1 Endomembrane protein 70 PALP PF00291.20 GAM27661.1 - 2.4e-80 270.0 0.1 5.3e-71 239.3 0.2 3.5 3 1 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme ACT_5 PF13710.1 GAM27661.1 - 0.01 15.6 0.3 0.029 14.1 0.2 1.8 1 0 0 1 1 1 0 ACT domain ACT_4 PF13291.1 GAM27661.1 - 0.016 15.5 0.3 0.097 13.0 0.1 2.4 2 0 0 2 2 2 0 ACT domain DUF2465 PF10239.4 GAM27663.1 - 7.3e-36 123.9 1.6 9.4e-36 123.6 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) DUF4233 PF14017.1 GAM27664.1 - 0.029 14.2 0.9 1.8 8.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Peptidase_A2E PF12382.3 GAM27664.1 - 0.087 12.6 0.2 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase DUF4137 PF13593.1 GAM27664.1 - 0.098 11.7 1.6 0.17 10.9 0.0 1.8 1 1 1 2 2 2 0 SBF-like CPA transporter family (DUF4137) DUF3021 PF11457.3 GAM27664.1 - 0.65 9.8 6.8 1.1 9.1 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) AT_hook PF02178.14 GAM27665.1 - 0.0096 15.4 3.6 0.022 14.4 2.5 1.6 1 0 0 1 1 1 1 AT hook motif Ank_2 PF12796.2 GAM27666.1 - 9.5e-35 118.8 0.5 9.1e-21 74.0 0.0 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM27666.1 - 8.2e-25 85.3 0.9 3.1e-07 29.8 0.2 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 GAM27666.1 - 7.9e-22 77.2 0.0 1.7e-12 47.5 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27666.1 - 4.3e-18 63.6 0.1 0.00032 20.6 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 GAM27666.1 - 2.8e-17 62.3 0.3 9.9e-06 25.6 0.1 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) gp45-slide_C PF09116.5 GAM27666.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal Abhydrolase_5 PF12695.2 GAM27667.1 - 1.6e-21 76.6 0.0 2.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM27667.1 - 1.2e-16 61.3 0.0 6.5e-15 55.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM27667.1 - 2.4e-11 43.6 0.0 9.2e-07 28.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 GAM27667.1 - 9.2e-08 32.0 0.0 0.00064 19.4 0.0 2.7 2 1 1 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 GAM27667.1 - 9.5e-08 31.5 0.0 1.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 GAM27667.1 - 3.4e-06 26.5 0.0 1.8e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 GAM27667.1 - 2.9e-05 23.6 0.0 0.04 13.3 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF818 PF05677.7 GAM27667.1 - 0.00026 19.8 0.0 0.0004 19.2 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.7 GAM27667.1 - 0.00029 19.4 0.1 0.00081 17.9 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 GAM27667.1 - 0.0019 17.7 0.0 0.0059 16.2 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 GAM27667.1 - 0.0037 16.7 0.0 0.007 15.8 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) PGAP1 PF07819.8 GAM27667.1 - 0.0093 15.5 0.0 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S15 PF02129.13 GAM27667.1 - 0.081 12.3 0.0 3.5 6.9 0.0 2.2 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.7 GAM27667.1 - 0.083 11.6 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.20 GAM27667.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 GAM27667.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S10 PF00450.17 GAM27668.1 - 8.1e-121 404.0 7.3 9.9e-121 403.7 5.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_35 PF01301.14 GAM27669.1 - 7.4e-107 357.3 0.1 1.1e-106 356.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 GAM27669.1 - 6e-15 55.2 0.2 2.5e-13 49.9 0.1 2.2 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 GAM27669.1 - 9.5e-06 25.8 4.0 1.1e-05 25.6 0.8 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Cellulase PF00150.13 GAM27669.1 - 0.0003 20.0 0.0 0.00065 18.9 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.17 GAM27670.1 - 1.4e-18 66.2 0.2 1.9e-18 65.8 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM27670.1 - 1.6e-13 50.4 0.1 2.7e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM27670.1 - 4e-07 29.7 0.5 6e-07 29.2 0.3 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM27670.1 - 0.037 13.8 0.1 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif ANF_receptor PF01094.23 GAM27671.1 - 0.88 8.2 9.1 1.3 7.6 6.2 1.4 1 1 0 1 1 1 0 Receptor family ligand binding region DUF1204 PF06721.6 GAM27672.1 - 0.28 10.4 2.1 0.29 10.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) TerC PF03741.11 GAM27672.1 - 1.3 8.3 6.4 1.6 8.1 4.5 1.1 1 0 0 1 1 1 0 Integral membrane protein TerC family AIF-MLS PF14962.1 GAM27672.1 - 4.9 6.7 12.9 5.6 6.5 8.9 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Nucleoporin_FG PF13634.1 GAM27673.1 - 2e-11 44.1 200.4 2.4e-09 37.3 30.4 6.4 2 2 2 4 4 4 2 Nucleoporin FG repeat region CorA PF01544.13 GAM27673.1 - 0.04 12.9 0.7 0.076 12.0 0.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3519 PF12033.3 GAM27673.1 - 0.041 14.0 1.7 0.88 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Snapin_Pallidin PF14712.1 GAM27673.1 - 0.19 12.0 4.1 2.3 8.5 1.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin APG17 PF04108.7 GAM27673.1 - 0.2 10.3 6.5 0.19 10.5 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 FNIP PF05725.7 GAM27674.1 - 4.2e-53 177.0 27.9 1.1e-08 34.9 0.1 10.1 7 2 2 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 GAM27674.1 - 0.00065 19.6 2.0 1.7 8.6 0.0 4.8 4 1 1 5 5 5 1 Protein of unknown function (DUF1769) FNIP PF05725.7 GAM27675.1 - 4.7e-114 372.1 52.1 2.6e-13 49.6 0.5 16.1 10 4 6 18 18 18 16 FNIP Repeat PspA_IM30 PF04012.7 GAM27676.1 - 0.068 12.5 0.1 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 PspA/IM30 family FNIP PF05725.7 GAM27677.1 - 2.4e-61 203.4 15.1 2.2e-12 46.6 0.1 7.7 7 0 0 7 7 7 6 FNIP Repeat Kinesin-related PF06548.6 GAM27677.1 - 0.021 13.3 0.2 0.029 12.9 0.1 1.1 1 0 0 1 1 1 0 Kinesin-related LRS4 PF10422.4 GAM27677.1 - 0.071 12.4 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Mucin PF01456.12 GAM27678.1 - 0.2 11.4 7.9 0.29 10.8 5.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MAP65_ASE1 PF03999.7 GAM27678.1 - 5.8 5.3 9.5 7.1 5.0 6.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF3450 PF11932.3 GAM27680.1 - 1.5 7.9 5.1 0.73 9.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PAP_assoc PF03828.14 GAM27681.1 - 9.5e-19 67.1 0.3 2.2e-18 65.9 0.2 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 GAM27681.1 - 2.2e-05 24.6 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain TPR_19 PF14559.1 GAM27682.1 - 2.4e-14 53.3 7.4 0.085 13.2 0.0 5.9 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 GAM27682.1 - 5e-11 42.2 20.3 0.5 11.1 0.2 9.2 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 GAM27682.1 - 3.1e-10 40.4 16.9 0.03 14.9 0.0 6.8 4 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 GAM27682.1 - 1.1e-07 31.3 7.4 0.5 10.0 0.0 4.8 4 0 0 4 4 4 4 TPR repeat TPR_17 PF13431.1 GAM27682.1 - 0.0012 18.9 0.4 0.51 10.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_3 PF13812.1 GAM27682.1 - 0.068 13.4 0.1 16 6.1 0.0 3.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain TPR_12 PF13424.1 GAM27682.1 - 0.15 11.9 18.7 4 7.4 0.2 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM27682.1 - 0.19 11.6 5.1 8.8 6.4 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM27682.1 - 0.32 11.0 19.7 13 6.0 0.1 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.9 GAM27683.1 - 1.1e-28 100.5 0.3 1.6e-28 99.9 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM27683.1 - 4.3e-17 62.2 0.8 3.3e-15 56.2 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 GAM27683.1 - 1.5e-11 44.7 0.1 1.9e-06 28.0 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM27683.1 - 0.00024 20.3 0.3 0.013 14.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM27683.1 - 0.00046 19.3 1.3 0.0027 16.8 0.0 2.4 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 GAM27683.1 - 0.00079 18.4 0.1 1.1 8.0 0.0 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 GAM27683.1 - 0.0044 17.2 0.2 0.019 15.2 0.0 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 GAM27683.1 - 0.011 14.6 3.5 0.3 9.8 0.8 2.7 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 GAM27683.1 - 0.011 15.7 0.1 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 GAM27683.1 - 0.021 13.2 0.5 0.23 9.8 0.3 2.3 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 GAM27683.1 - 0.035 14.1 0.2 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 GAM27683.1 - 0.1 11.4 10.9 0.46 9.2 0.6 3.6 2 2 2 4 4 4 0 Glucose inhibited division protein A DAO PF01266.19 GAM27683.1 - 0.2 10.5 1.6 9.1 5.0 0.5 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase KH_3 PF13014.1 GAM27684.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 KH domain Prefoldin PF02996.12 GAM27685.1 - 1.7e-24 85.7 2.7 1.7e-24 85.7 1.9 1.6 2 1 0 2 2 2 1 Prefoldin subunit TACC PF05010.9 GAM27685.1 - 0.0015 18.3 7.1 0.0022 17.7 4.9 1.3 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) TOM20_plant PF06552.7 GAM27685.1 - 0.091 12.3 0.2 0.091 12.3 0.1 1.6 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 LXG PF04740.7 GAM27685.1 - 0.24 11.1 10.4 2.9 7.6 3.3 2.2 2 0 0 2 2 2 0 LXG domain of WXG superfamily TLV_coat PF00429.14 GAM27685.1 - 0.47 8.8 9.0 0.58 8.5 0.5 2.1 2 0 0 2 2 2 0 ENV polyprotein (coat polyprotein) Nup88 PF10168.4 GAM27685.1 - 5.2 4.7 10.9 7.8 4.1 7.6 1.3 1 1 0 1 1 1 0 Nuclear pore component DUF1640 PF07798.6 GAM27685.1 - 5.4 7.0 14.9 7.7 6.5 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) MIP PF00230.15 GAM27686.1 - 3.5e-49 167.3 14.8 4.2e-49 167.0 10.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein CBS PF00571.23 GAM27687.1 - 3.1e-21 74.8 1.8 3.1e-07 30.0 0.1 4.9 4 1 0 4 4 4 4 CBS domain FNIP PF05725.7 GAM27688.1 - 1.9e-53 178.1 32.6 7.4e-15 54.6 0.9 10.2 6 4 3 9 9 9 8 FNIP Repeat UPF0547 PF10571.4 GAM27688.1 - 0.31 10.7 1.4 0.67 9.7 0.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 FMO-like PF00743.14 GAM27689.1 - 2.6e-49 167.8 0.0 4.1e-49 167.1 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 GAM27689.1 - 4.4e-22 79.1 0.0 3.5e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 GAM27689.1 - 1.3e-12 47.9 0.5 4.9e-07 30.0 0.2 3.9 4 1 1 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM27689.1 - 6.2e-12 45.3 0.1 6e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 GAM27689.1 - 3.7e-11 43.2 0.0 2.7e-06 27.4 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 GAM27689.1 - 1.6e-10 40.4 0.3 3.3e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 GAM27689.1 - 2.8e-10 40.1 0.2 2.3e-05 24.2 0.0 3.9 2 2 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 GAM27689.1 - 1.1e-09 37.6 0.4 0.0012 17.7 0.8 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 GAM27689.1 - 2.7e-07 29.8 0.2 0.0014 17.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 GAM27689.1 - 3.5e-07 29.6 0.0 1.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM27689.1 - 7.3e-07 28.5 0.1 0.018 14.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 GAM27689.1 - 3.3e-06 26.2 0.9 0.0014 17.5 0.3 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 GAM27689.1 - 5.1e-06 25.2 0.7 0.0042 15.6 0.0 2.8 3 0 0 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.13 GAM27689.1 - 2.2e-05 24.1 0.2 0.00015 21.4 0.0 2.3 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 GAM27689.1 - 3.6e-05 22.9 0.4 0.0036 16.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 GAM27689.1 - 9.9e-05 22.1 0.0 0.0038 16.9 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 GAM27689.1 - 0.00017 21.7 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 GAM27689.1 - 0.00025 21.1 0.1 0.0015 18.5 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 GAM27689.1 - 0.00031 21.1 0.1 0.0097 16.3 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 GAM27689.1 - 0.0017 17.7 0.0 0.0044 16.4 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 GAM27689.1 - 0.0029 16.9 0.1 0.0029 16.9 0.0 2.3 3 0 0 3 3 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 GAM27689.1 - 0.0042 16.5 0.1 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 GAM27689.1 - 0.0066 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 GAM27689.1 - 0.011 15.9 0.0 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 GAM27689.1 - 0.011 15.2 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 GAM27689.1 - 0.024 13.5 0.0 0.25 10.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 GAM27689.1 - 0.025 14.5 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.10 GAM27689.1 - 0.03 14.1 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_trans_4_4 PF13579.1 GAM27689.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Mqo PF06039.10 GAM27689.1 - 0.093 10.8 0.0 0.18 9.9 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Saccharop_dh PF03435.13 GAM27689.1 - 0.097 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ThiF PF00899.16 GAM27689.1 - 0.19 11.5 1.0 0.37 10.6 0.2 1.9 2 0 0 2 2 1 0 ThiF family PLAC8 PF04749.12 GAM27690.1 - 9.5e-14 51.8 20.7 1.1e-13 51.6 14.4 1.0 1 0 0 1 1 1 1 PLAC8 family Cyt-b5 PF00173.23 GAM27691.1 - 4.4e-06 26.4 0.2 1.2e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pox_RNA_Pol_19 PF05320.7 GAM27691.1 - 0.058 13.1 1.0 0.066 12.9 0.2 1.6 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit rve_2 PF13333.1 GAM27691.1 - 0.26 11.3 1.9 0.57 10.3 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain Myosin_head PF00063.16 GAM27692.1 - 1e-261 869.9 0.5 1.3e-261 869.6 0.4 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM27692.1 - 5.6e-48 162.9 2.2 8.8e-48 162.2 1.5 1.3 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 GAM27692.1 - 6.9e-09 34.5 6.5 0.00015 21.0 0.4 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_18 PF13238.1 GAM27692.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM27692.1 - 0.013 15.6 0.0 0.056 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 GAM27692.1 - 0.016 15.1 0.3 0.26 11.2 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 GAM27692.1 - 0.025 13.6 0.0 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 GAM27692.1 - 0.03 13.2 0.0 0.066 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 GAM27692.1 - 0.031 13.9 0.0 11 5.6 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 GAM27692.1 - 0.049 14.4 0.0 0.27 12.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAM27692.1 - 0.055 13.2 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Hpr_kinase_C PF07475.7 GAM27692.1 - 0.07 12.4 0.2 8.9 5.5 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain UQ_con PF00179.21 GAM27693.1 - 2.1e-51 173.0 0.0 2.4e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM27693.1 - 0.00018 21.2 0.0 0.00022 20.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM27693.1 - 0.00077 19.3 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 GAM27693.1 - 0.062 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain UPF0054 PF02130.12 GAM27694.1 - 0.0047 16.2 1.7 0.012 14.8 0.8 1.9 1 1 0 1 1 1 1 Uncharacterized protein family UPF0054 Ank_2 PF12796.2 GAM27695.1 - 1.6e-07 31.5 0.0 0.0075 16.5 0.0 4.2 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM27695.1 - 0.00018 21.6 0.3 3.6 7.9 0.0 4.4 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM27695.1 - 0.00073 19.9 1.1 32 5.2 0.0 5.2 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27695.1 - 0.0011 18.9 2.1 2.2 8.7 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat BRCT PF00533.21 GAM27696.1 - 7.7e-10 38.7 0.5 1.8e-09 37.6 0.3 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM27696.1 - 0.00019 21.2 0.0 0.00041 20.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Cu2_monoox_C PF03712.10 GAM27696.1 - 0.079 12.3 0.1 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Gtr1_RagA PF04670.7 GAM27697.1 - 4e-71 238.8 3.2 5.4e-71 238.4 2.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM27697.1 - 4.9e-06 27.0 0.1 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27697.1 - 8.7e-06 25.0 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM27697.1 - 2.5e-05 23.5 0.1 3.9e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM27697.1 - 0.00064 19.6 0.1 0.004 17.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 GAM27697.1 - 0.00098 18.5 0.2 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Stirrup PF09061.1 GAM27697.1 - 0.079 12.8 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Stirrup Solute_trans_a PF03619.11 GAM27698.1 - 2.3e-91 305.9 20.6 3.1e-91 305.5 14.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-B_box PF00643.19 GAM27699.1 - 2.9e-06 27.0 4.0 6.7e-06 25.9 2.8 1.6 1 0 0 1 1 1 1 B-box zinc finger PAT1 PF09770.4 GAM27699.1 - 0.17 10.0 18.6 0.25 9.5 12.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 GAM27699.1 - 0.19 10.7 5.1 0.31 10.0 3.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus G0-G1_switch_2 PF15103.1 GAM27699.1 - 0.21 11.7 2.9 0.5 10.6 1.7 1.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF2149 PF09919.4 GAM27699.1 - 0.57 10.3 2.7 1.6 8.8 1.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) CBP4 PF07960.6 GAM27699.1 - 0.89 9.1 13.0 7.1 6.2 0.1 2.3 2 0 0 2 2 2 0 CBP4 FCP1_C PF09309.5 GAM27699.1 - 2.1 7.5 9.6 3.7 6.7 6.6 1.3 1 0 0 1 1 1 0 FCP1, C-terminal WASH-7_C PF14746.1 GAM27699.1 - 2.3 7.7 11.6 0.94 9.0 5.5 2.0 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal RCR PF12273.3 GAM27699.1 - 3.9 8.0 17.7 7.6 7.1 12.3 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HnRNPA1 PF11627.3 GAM27699.1 - 6 7.1 9.6 13 6.0 6.7 1.6 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 Kelch_6 PF13964.1 GAM27700.1 - 9.4e-14 50.9 6.4 6.7e-05 22.8 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 GAM27700.1 - 5.7e-13 48.1 1.2 7.8e-05 22.1 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM27700.1 - 7.5e-12 44.8 8.6 3.7e-05 23.3 0.1 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM27700.1 - 3.1e-08 33.5 5.4 0.024 14.8 0.1 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM27700.1 - 2.8e-07 30.0 2.6 0.046 13.4 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 GAM27700.1 - 0.028 14.3 11.8 0.067 13.1 0.1 3.8 4 0 0 4 4 4 0 Kelch motif tRNA-synt_His PF13393.1 GAM27701.1 - 1.7e-41 142.3 0.0 2.6e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 GAM27701.1 - 4.9e-27 94.6 0.0 7e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM27701.1 - 2.3e-11 43.4 0.1 9.3e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.15 GAM27701.1 - 0.00026 20.2 0.0 0.001 18.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 GAM27701.1 - 0.029 13.1 0.1 0.77 8.4 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) CBFD_NFYB_HMF PF00808.18 GAM27702.1 - 2.7e-19 68.9 0.4 4.5e-19 68.2 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MOR2-PAG1_N PF14222.1 GAM27702.1 - 0.061 12.0 0.5 0.11 11.2 0.1 1.5 1 1 0 1 1 1 0 Cell morphogenesis N-terminal Histone PF00125.19 GAM27702.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 zf-RING_2 PF13639.1 GAM27703.1 - 2.7e-11 43.1 6.9 5.5e-11 42.1 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM27703.1 - 1.9e-08 33.8 4.6 3.2e-08 33.1 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM27703.1 - 5.3e-07 29.5 7.2 9.2e-07 28.7 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM27703.1 - 7.5e-07 28.7 5.7 1.5e-06 27.7 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM27703.1 - 1.6e-06 28.1 6.7 1.6e-06 28.1 4.7 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM27703.1 - 7e-06 25.6 4.2 1.3e-05 24.7 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM27703.1 - 0.00013 21.6 4.2 0.00022 20.8 1.2 2.6 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 GAM27703.1 - 0.0013 18.2 1.7 0.0013 18.2 1.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 GAM27703.1 - 0.0038 17.0 3.3 0.0038 17.0 2.3 2.3 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Med15 PF09606.5 GAM27703.1 - 0.017 13.3 85.2 0.021 13.0 59.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C3HC4_4 PF15227.1 GAM27703.1 - 0.042 13.7 3.7 0.11 12.3 2.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 GAM27703.1 - 0.72 9.9 6.5 1.8 8.6 4.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 GAM27703.1 - 0.78 9.3 3.6 2.3 7.8 2.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_60s PF00428.14 GAM27703.1 - 3.7 8.0 8.4 7.1 7.1 4.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4570 PF15134.1 GAM27703.1 - 5.5 6.8 24.2 2.8 7.8 12.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF2054 PF10218.4 GAM27704.1 - 1.2e-21 76.9 18.1 4e-20 72.0 12.6 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) PH PF00169.24 GAM27707.1 - 4.1e-08 33.3 0.1 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 GAM27707.1 - 0.042 13.7 0.1 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 PH domain PEPCK_ATP PF01293.15 GAM27707.1 - 0.1 11.1 0.1 0.13 10.7 0.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Amidohydro_1 PF01979.15 GAM27708.1 - 1.3e-42 146.6 0.0 1.6e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 GAM27708.1 - 4.8e-08 32.7 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 GAM27708.1 - 0.00075 18.8 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 GAM27708.1 - 0.032 14.2 0.0 0.085 12.8 0.0 2.0 1 1 0 1 1 1 0 Amidohydrolase PIP5K PF01504.13 GAM27709.1 - 3.9e-78 262.0 0.1 3.9e-78 262.0 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2201_N PF13203.1 GAM27709.1 - 3.6 6.6 13.9 0.031 13.4 3.5 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain BTB_2 PF02214.17 GAM27711.1 - 5.9e-21 74.4 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Smg4_UPF3 PF03467.10 GAM27715.1 - 5.6e-12 46.0 2.3 7.5e-12 45.6 1.6 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family UPF0449 PF15136.1 GAM27715.1 - 0.015 15.5 1.4 0.07 13.3 0.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 AAA_23 PF13476.1 GAM27715.1 - 0.12 12.6 6.6 0.14 12.4 4.6 1.1 1 0 0 1 1 1 0 AAA domain BRICHOS PF04089.9 GAM27715.1 - 0.25 11.2 1.2 2.3 8.1 0.0 2.5 2 1 0 2 2 2 0 BRICHOS domain APG6 PF04111.7 GAM27715.1 - 1.2 8.1 8.4 1.7 7.6 5.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 GAM27716.1 - 0.017 15.4 11.9 0.02 15.1 8.3 1.1 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.1 GAM27716.1 - 0.076 13.0 10.4 0.11 12.5 7.2 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Oxysterol_BP PF01237.13 GAM27716.1 - 0.08 11.4 6.9 0.082 11.3 4.8 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein IATP PF04568.7 GAM27716.1 - 0.12 12.3 19.3 0.062 13.3 3.5 2.3 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Matrilin_ccoil PF10393.4 GAM27716.1 - 0.13 11.6 5.5 0.26 10.6 3.8 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin APG6 PF04111.7 GAM27716.1 - 0.21 10.5 12.3 0.22 10.5 8.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 GAM27716.1 - 0.25 10.6 6.5 0.28 10.4 4.5 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Ax_dynein_light PF10211.4 GAM27716.1 - 0.25 11.1 14.5 0.31 10.8 10.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3573 PF12097.3 GAM27716.1 - 0.35 9.4 2.5 0.32 9.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF342 PF03961.8 GAM27716.1 - 0.43 8.9 13.1 0.45 8.8 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2968 PF11180.3 GAM27716.1 - 0.5 9.7 8.9 0.96 8.8 5.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Syntaxin-6_N PF09177.6 GAM27716.1 - 0.53 10.7 10.0 0.55 10.6 5.9 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HemX PF04375.9 GAM27716.1 - 0.64 8.5 8.7 0.77 8.2 6.1 1.2 1 0 0 1 1 1 0 HemX DUF913 PF06025.7 GAM27716.1 - 0.76 8.4 4.0 0.77 8.4 2.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4094 PF13334.1 GAM27716.1 - 1 9.7 6.4 1.3 9.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) V_ATPase_I PF01496.14 GAM27716.1 - 2 6.1 10.7 2 6.1 7.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 GAM27716.1 - 2.9 8.3 10.8 9.7 6.7 7.5 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.7 GAM27716.1 - 3.3 8.1 7.8 0.42 11.0 1.0 2.3 1 1 1 2 2 2 0 SlyX OmpH PF03938.9 GAM27716.1 - 5.1 7.0 14.7 7.2 6.5 10.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 GAM27716.1 - 5.5 5.8 10.2 6.7 5.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 GAM27716.1 - 5.6 5.8 12.4 6 5.7 8.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GIY-YIG PF01541.19 GAM27716.1 - 6.5 7.1 8.5 42 4.6 0.0 2.1 1 1 1 2 2 2 0 GIY-YIG catalytic domain DUF3513 PF12026.3 GAM27716.1 - 6.9 6.1 10.3 8.8 5.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) bZIP_2 PF07716.10 GAM27716.1 - 8.6 6.2 21.7 0.072 12.9 7.7 2.5 1 1 1 2 2 1 0 Basic region leucine zipper eIF-1a PF01176.14 GAM27717.1 - 6e-13 48.0 0.1 8.4e-13 47.5 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pyr_redox_2 PF07992.9 GAM27718.1 - 4.7e-12 46.2 0.0 9.3e-12 45.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 GAM27718.1 - 2.2e-05 24.2 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 GAM27718.1 - 0.00015 20.8 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 GAM27718.1 - 0.00026 19.7 0.0 0.00072 18.2 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 GAM27718.1 - 0.0036 17.6 0.0 0.016 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 GAM27718.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 GAM27718.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FNIP PF05725.7 GAM27719.1 - 7.6e-36 121.8 21.1 6.7e-10 38.7 0.0 8.7 2 2 7 10 10 10 10 FNIP Repeat S10_plectin PF03501.10 GAM27719.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain LRR_1 PF00560.28 GAM27719.1 - 3.9 7.8 11.5 58 4.2 1.8 5.5 5 2 0 5 5 5 0 Leucine Rich Repeat Cys_Met_Meta_PP PF01053.15 GAM27720.1 - 2.1e-152 506.9 0.0 2.3e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 GAM27720.1 - 1.3e-06 27.6 0.1 1.9e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAM27720.1 - 2.4e-05 23.5 0.2 4.9e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 GAM27720.1 - 7.2e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ArfGap PF01412.13 GAM27721.1 - 2.8e-25 88.3 3.0 6.3e-25 87.2 2.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SH3_9 PF14604.1 GAM27721.1 - 5.8e-08 32.1 0.4 6.1e-07 28.9 0.3 2.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM27721.1 - 5.6e-07 28.8 0.1 1.4e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM27721.1 - 0.00022 20.6 0.0 0.0011 18.3 0.0 2.3 2 1 0 2 2 2 1 Variant SH3 domain RBD PF02196.10 GAM27721.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain PH PF00169.24 GAM27721.1 - 0.066 13.4 0.6 0.83 9.8 0.1 2.9 3 0 0 3 3 3 0 PH domain PI3K_rbd PF00794.13 GAM27721.1 - 0.081 12.8 0.5 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain Pep3_Vps18 PF05131.9 GAM27722.1 - 3.6e-41 140.0 0.0 1.4e-40 138.0 0.0 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 GAM27722.1 - 6.8e-12 45.2 2.9 6.8e-12 45.2 2.0 3.5 2 1 0 3 3 3 1 Region in Clathrin and VPS zf-RING_5 PF14634.1 GAM27722.1 - 4.1e-05 23.2 1.2 0.00014 21.4 0.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM27722.1 - 0.0001 22.0 1.1 0.00039 20.2 0.8 2.1 1 0 0 1 1 1 1 Ring finger domain DUF2732 PF10809.3 GAM27722.1 - 0.0017 17.8 0.4 2.9 7.5 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2732) DUF2175 PF09943.4 GAM27722.1 - 0.0069 16.4 0.3 0.026 14.5 0.2 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 GAM27722.1 - 0.014 15.3 1.0 0.059 13.4 0.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM27722.1 - 0.043 13.4 1.1 0.12 12.0 0.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_7 PF13176.1 GAM27722.1 - 0.047 13.4 5.3 32 4.6 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM27722.1 - 0.083 12.5 9.0 1.8 8.3 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_2 PF10367.4 GAM27722.1 - 0.39 10.9 4.3 0.21 11.8 0.1 2.6 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 TPR_2 PF07719.12 GAM27722.1 - 1.2 9.1 6.0 8.5 6.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 GAM27722.1 - 6.8 6.7 8.6 6.9 6.7 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M1 PF01433.15 GAM27723.1 - 3.3e-115 385.3 7.6 3.3e-115 385.3 5.2 2.1 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 GAM27723.1 - 2.4e-29 102.5 0.9 6.7e-29 101.1 0.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 GAM27723.1 - 1.4e-17 63.9 0.1 3.3e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily CBFD_NFYB_HMF PF00808.18 GAM27724.1 - 6e-19 67.8 0.6 9.3e-19 67.2 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 GAM27724.1 - 1.1e-07 31.9 0.1 1.8e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ndc1_Nup PF09531.5 GAM27724.1 - 3.8 5.8 11.7 4.8 5.4 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3505 PF12013.3 GAM27724.1 - 4.1 7.6 19.0 0.17 12.1 8.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Methyltrans_SAM PF10672.4 GAM27725.1 - 1.4e-19 70.0 0.0 2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase MTS PF05175.9 GAM27725.1 - 0.00022 20.6 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 GAM27725.1 - 0.0012 18.9 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 GAM27725.1 - 0.033 13.5 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.1 GAM27725.1 - 0.12 13.2 0.0 0.29 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arm PF00514.18 GAM27726.1 - 0.11 12.4 3.6 5.9 6.8 0.2 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PGAP1 PF07819.8 GAM27727.1 - 0.00028 20.5 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 GAM27727.1 - 0.00065 19.0 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 GAM27727.1 - 0.00088 19.2 0.1 0.0019 18.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 GAM27727.1 - 0.0074 16.0 0.1 0.023 14.4 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arm_2 PF04826.8 GAM27727.1 - 0.012 14.7 2.2 0.16 11.0 0.1 2.3 1 1 1 2 2 2 0 Armadillo-like XRN_N PF03159.13 GAM27728.1 - 1.1e-98 329.4 0.1 1.1e-98 329.4 0.1 4.0 4 0 0 4 4 4 2 XRN 5'-3' exonuclease N-terminus Ribosomal_60s PF00428.14 GAM27728.1 - 1.7 9.1 11.2 6.6 7.2 7.8 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M24 PF00557.19 GAM27729.1 - 2e-54 184.3 0.0 2.8e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 GAM27729.1 - 4.8e-29 100.4 0.0 8.4e-29 99.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.2 GAM27729.1 - 0.052 13.1 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) bZIP_1 PF00170.16 GAM27730.1 - 0.00011 22.0 12.1 0.00036 20.4 8.4 1.9 1 1 0 1 1 1 1 bZIP transcription factor Semialdhyde_dh PF01118.19 GAM27730.1 - 0.03 14.6 0.2 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PNRC PF15365.1 GAM27731.1 - 3.3e-13 49.4 0.6 3.3e-13 49.4 0.4 2.5 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator DUF1394 PF07159.7 GAM27733.1 - 1.3e-138 461.2 0.6 1.4e-138 461.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF1098 PF06497.6 GAM27733.1 - 0.086 12.9 0.3 0.68 10.0 0.1 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1098) Complex1_LYR PF05347.10 GAM27734.1 - 2.1e-07 30.6 1.2 3.3e-07 30.0 0.2 1.6 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM27734.1 - 0.00039 20.5 4.0 0.00069 19.7 0.5 2.1 1 1 1 2 2 2 1 Complex1_LYR-like EF-hand_3 PF09069.6 GAM27734.1 - 0.038 14.0 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 EF-hand DUF2325 PF10087.4 GAM27734.1 - 0.11 12.3 0.3 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_10 PF13460.1 GAM27735.1 - 2.9e-15 56.7 0.0 4.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM27735.1 - 1.5e-14 53.5 0.0 5.7e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 GAM27735.1 - 7.9e-12 45.1 0.1 5.2e-11 42.4 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 GAM27735.1 - 3.2e-08 33.1 0.0 4.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 GAM27735.1 - 4.2e-08 32.2 0.1 1.1e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 GAM27735.1 - 4.5e-07 29.0 0.9 0.0013 17.6 0.6 3.2 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 GAM27735.1 - 0.0073 15.3 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 GAM27735.1 - 0.015 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CCDC155 PF14662.1 GAM27736.1 - 0.0084 15.7 0.8 0.012 15.2 0.5 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Prenyltransf PF01255.14 GAM27737.1 - 2.3e-76 255.8 1.6 2.3e-76 255.8 1.1 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase KIX PF02172.11 GAM27737.1 - 0.022 14.8 0.2 0.076 13.0 0.1 1.9 1 0 0 1 1 1 0 KIX domain DHHW PF14286.1 GAM27737.1 - 0.031 13.6 6.0 0.064 12.5 4.2 1.5 1 0 0 1 1 1 0 DHHW protein Mem_trans PF03547.13 GAM27737.1 - 0.095 10.9 2.2 1 7.5 0.4 2.1 2 0 0 2 2 2 0 Membrane transport protein Otopetrin PF03189.8 GAM27737.1 - 0.27 10.1 7.0 0.06 12.3 1.6 1.9 2 0 0 2 2 2 0 Otopetrin Zip PF02535.17 GAM27737.1 - 0.5 9.3 6.3 1.8 7.5 4.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Spindle_Spc25 PF08234.7 GAM27738.1 - 2.2e-21 75.6 1.4 1e-20 73.5 0.1 2.4 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF3450 PF11932.3 GAM27738.1 - 0.034 13.3 4.7 0.064 12.5 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.4 GAM27738.1 - 1.3 8.9 7.7 2.2 8.2 5.3 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein TMF_DNA_bd PF12329.3 GAM27738.1 - 4.3 7.2 8.8 3.1 7.6 3.3 2.6 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding RhoGAP PF00620.22 GAM27739.1 - 4.4e-28 97.7 0.0 1.6e-27 95.9 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 GAM27739.1 - 1.6e-10 41.0 0.0 6.4e-10 39.0 0.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF605 PF04652.11 GAM27739.1 - 6.6 6.0 32.8 1.1 8.5 19.5 1.8 2 0 0 2 2 2 0 Vta1 like TRAP_alpha PF03896.11 GAM27740.1 - 4.5e-37 127.5 0.1 5e-37 127.4 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Chordopox_A13L PF05961.6 GAM27740.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Glycos_transf_4 PF00953.16 GAM27740.1 - 0.059 13.1 0.2 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 4 tRNA_anti-like PF12869.2 GAM27740.1 - 0.12 11.8 0.1 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA_anti-like DUF1616 PF07760.6 GAM27740.1 - 0.14 11.2 0.1 0.14 11.2 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1616) Ras PF00071.17 GAM27741.1 - 2.1e-63 212.5 0.8 2.5e-63 212.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27741.1 - 1e-18 67.9 0.0 1.7e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM27741.1 - 5e-16 58.4 0.1 6.2e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM27741.1 - 3.9e-06 26.1 0.1 4.6e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM27741.1 - 3.1e-05 23.4 0.4 7e-05 22.3 0.3 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM27741.1 - 0.00021 21.1 0.1 0.00043 20.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 GAM27741.1 - 0.00051 20.2 0.1 0.2 11.8 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 GAM27741.1 - 0.00093 18.4 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 GAM27741.1 - 0.0019 18.3 0.0 0.0077 16.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 GAM27741.1 - 0.0047 16.2 0.1 0.042 13.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 GAM27741.1 - 0.0058 16.6 0.0 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAM27741.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 GAM27741.1 - 0.026 13.6 0.1 0.059 12.5 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM27741.1 - 0.036 13.5 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Las1 PF04031.8 GAM27743.1 - 1.1e-39 135.5 2.8 2e-39 134.6 1.9 1.5 1 0 0 1 1 1 1 Las1-like BTB PF00651.26 GAM27744.1 - 2.1e-16 59.8 1.8 2.3e-09 37.1 0.1 3.3 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.10 GAM27744.1 - 3.9e-10 39.4 6.9 2.6e-09 36.8 0.1 3.0 3 0 0 3 3 3 2 BTB And C-terminal Kelch Ank_2 PF12796.2 GAM27745.1 - 3.6e-25 88.1 4.7 6.8e-10 39.1 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM27745.1 - 2.1e-19 68.2 20.0 1.4e-05 24.6 0.1 7.2 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 GAM27745.1 - 4.2e-19 68.1 15.4 2.7e-08 33.7 0.3 4.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM27745.1 - 1.5e-18 66.7 8.7 9.5e-08 32.3 0.2 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27745.1 - 8.3e-11 41.0 7.8 0.016 15.4 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Cyclin PF08613.6 GAM27746.1 - 0.00016 22.1 0.3 0.00016 22.1 0.2 2.4 2 1 0 2 2 2 1 Cyclin DUF4446 PF14584.1 GAM27746.1 - 1.6 8.5 6.0 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF605 PF04652.11 GAM27746.1 - 2.6 7.3 23.7 4 6.7 16.4 1.2 1 0 0 1 1 1 0 Vta1 like RCR PF12273.3 GAM27746.1 - 3.6 8.1 14.6 0.63 10.6 6.7 2.0 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TFIIA PF03153.8 GAM27746.1 - 5.1 6.8 18.9 7.7 6.3 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_3 PF01596.12 GAM27747.1 - 1.9e-62 209.9 0.6 2.1e-62 209.8 0.4 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAM27747.1 - 7e-14 52.5 0.0 8.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM27747.1 - 3e-05 24.5 0.1 5.7e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM27747.1 - 0.0004 20.0 0.1 0.00051 19.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM27747.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM27747.1 - 0.023 13.7 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 GAM27747.1 - 0.048 14.1 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 GAM27747.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_2 PF04059.7 GAM27747.1 - 0.11 12.5 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 PCMT PF01135.14 GAM27747.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Kelch_4 PF13418.1 GAM27748.1 - 9.5e-11 41.3 4.8 1.6e-05 24.5 0.2 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM27748.1 - 1.2e-09 37.5 8.2 9.9e-05 21.8 0.1 4.3 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 GAM27748.1 - 6.9e-07 29.1 11.0 0.03 14.5 0.1 4.7 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM27748.1 - 5.7e-06 26.3 1.4 0.039 14.1 0.0 4.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM27748.1 - 0.0028 17.3 2.8 0.89 9.4 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM27748.1 - 0.005 16.7 5.4 0.018 15.0 0.1 3.2 3 0 0 3 3 3 1 Kelch motif Nckap1 PF09735.4 GAM27749.1 - 0.00082 16.9 0.6 0.0011 16.6 0.4 1.3 1 1 0 1 1 1 1 Membrane-associated apoptosis protein zf-B_box PF00643.19 GAM27749.1 - 0.00087 19.1 7.2 0.0018 18.1 5.0 1.5 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 GAM27749.1 - 0.021 14.6 1.1 0.063 13.1 0.8 1.8 1 0 0 1 1 1 0 IBR domain Seryl_tRNA_N PF02403.17 GAM27749.1 - 0.36 10.8 3.8 0.4 10.7 1.3 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FYVE_2 PF02318.11 GAM27749.1 - 0.56 10.1 8.3 0.17 11.7 2.9 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger Mer2 PF09074.5 GAM27750.1 - 0.022 14.7 1.9 0.034 14.0 0.8 1.7 2 0 0 2 2 2 0 Mer2 DUF2513 PF10711.4 GAM27750.1 - 0.075 13.1 0.3 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) DUF3525 PF12039.3 GAM27750.1 - 0.083 11.3 0.2 0.089 11.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Kelch_6 PF13964.1 GAM27751.1 - 0.001 19.1 2.5 0.22 11.7 0.1 3.7 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 GAM27751.1 - 0.036 13.6 3.1 2.5 7.7 0.1 3.2 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.1 GAM27751.1 - 0.066 12.9 0.4 13 5.6 0.1 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM27752.1 - 0.0016 18.4 0.4 0.37 11.0 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 GAM27752.1 - 0.0032 17.1 0.0 0.56 10.0 0.0 2.5 2 0 0 2 2 2 1 Kelch motif DUF1877 PF08974.5 GAM27752.1 - 0.022 14.4 0.7 1.2 8.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1877) Kelch_1 PF01344.20 GAM27752.1 - 0.053 13.0 1.1 1.9 8.1 0.6 3.0 2 1 0 2 2 2 0 Kelch motif Kelch_5 PF13854.1 GAM27752.1 - 0.082 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.1 GAM27752.1 - 0.15 11.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF3347 PF11827.3 GAM27752.1 - 0.19 11.7 1.4 0.3 11.0 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Kelch_4 PF13418.1 GAM27753.1 - 1.3e-13 50.4 7.2 1.5e-05 24.6 0.1 4.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM27753.1 - 2e-11 43.5 14.3 1.1e-05 25.3 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM27753.1 - 3.6e-10 39.2 9.9 0.004 16.6 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM27753.1 - 7.1e-07 29.2 3.8 0.052 13.7 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM27753.1 - 4.3e-06 26.2 3.7 0.019 14.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM27753.1 - 0.00039 20.3 5.8 0.12 12.3 0.1 3.5 3 0 0 3 3 3 2 Kelch motif Methyltransf_3 PF01596.12 GAM27754.1 - 9.2e-70 233.8 0.1 1e-69 233.6 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 GAM27754.1 - 1.6e-14 54.5 0.0 2.5e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM27754.1 - 1.2e-06 28.1 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM27754.1 - 1.7e-06 28.6 0.0 5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM27754.1 - 0.00045 20.2 0.0 0.00092 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM27754.1 - 0.0021 17.1 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 GAM27754.1 - 0.0033 17.8 0.0 0.007 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM27754.1 - 0.0075 16.6 0.0 0.023 15.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 GAM27754.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 GAM27754.1 - 0.023 13.8 0.2 0.2 10.7 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 GAM27754.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.21 GAM27754.1 - 0.085 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RESP18 PF14948.1 GAM27755.1 - 0.0013 18.7 0.3 1.2 9.2 0.0 2.8 2 0 0 2 2 2 2 RESP18 domain Ferritin PF00210.19 GAM27755.1 - 0.0037 17.0 0.0 0.0096 15.6 0.0 1.6 1 0 0 1 1 1 1 Ferritin-like domain EamA PF00892.15 GAM27756.1 - 2.5e-21 76.0 32.0 2.7e-11 43.6 7.9 2.6 2 0 0 2 2 2 2 EamA-like transporter family Atrophin-1 PF03154.10 GAM27756.1 - 1.6 6.7 11.2 0.29 9.2 5.2 1.5 2 0 0 2 2 2 0 Atrophin-1 family DUF1129 PF06570.6 GAM27756.1 - 5.5 6.2 10.1 2.8 7.1 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) NLPC_P60 PF00877.14 GAM27757.1 - 2.1e-12 46.7 0.0 1.8e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 NlpC/P60 family DUF605 PF04652.11 GAM27758.1 - 0.4 10.0 32.3 0.043 13.2 16.7 2.1 2 0 0 2 2 2 0 Vta1 like WD40 PF00400.27 GAM27759.1 - 5.4e-32 108.5 8.5 3.2e-08 33.1 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat Bromodomain PF00439.20 GAM27759.1 - 1.4e-13 50.5 0.1 4e-13 49.0 0.1 1.8 2 0 0 2 2 2 1 Bromodomain Lung_7-TM_R PF06814.8 GAM27760.1 - 3.5e-65 219.8 24.8 3.5e-65 219.8 17.2 1.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor FA_desaturase PF00487.19 GAM27760.1 - 1.2 8.5 16.9 0.52 9.7 3.9 2.2 2 0 0 2 2 2 0 Fatty acid desaturase Ammonium_transp PF00909.16 GAM27761.1 - 3.1e-106 355.2 31.2 3.5e-106 355.0 21.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ank_2 PF12796.2 GAM27762.1 - 0.0041 17.4 0.1 1.5 9.2 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Peptidase_M3 PF01432.15 GAM27763.1 - 1.5e-101 340.6 1.4 1.5e-101 340.6 1.0 1.5 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 GAM27763.1 - 0.082 12.2 0.3 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Dict-STAT-coil PF09267.5 GAM27764.1 - 1.7e-38 131.3 16.4 1.7e-38 131.3 11.4 2.1 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 GAM27764.1 - 2.1e-10 40.2 0.0 5.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.9 GAM27764.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain PG_binding_1 PF01471.13 GAM27765.1 - 4.2e-07 29.8 0.0 7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Putative peptidoglycan binding domain YkuD PF03734.9 GAM27765.1 - 0.00068 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Adaptin_N PF01602.15 GAM27766.1 - 3.4e-116 388.6 10.6 4.3e-116 388.3 7.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 GAM27766.1 - 9e-27 93.2 0.0 6.5e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 GAM27766.1 - 1.2e-18 67.4 0.3 1.2e-18 67.4 0.2 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 GAM27766.1 - 0.00047 20.3 0.2 0.35 11.1 0.0 3.1 3 0 0 3 3 3 2 HEAT repeats Ribonuc_red_sm PF00268.16 GAM27767.1 - 1e-120 402.0 1.3 1.2e-120 401.7 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Pkinase PF00069.20 GAM27768.1 - 2e-67 227.0 2.5 4.6e-67 225.9 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27768.1 - 1.7e-25 89.5 1.1 1.9e-25 89.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27768.1 - 1.6e-05 24.0 0.0 3.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 GAM27769.1 - 1.6e-70 237.2 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27769.1 - 3.3e-36 124.7 0.0 4.7e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27769.1 - 4.9e-07 28.9 0.0 7.9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 GAM27769.1 - 0.00011 21.5 0.4 0.00019 20.8 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_C PF00433.19 GAM27769.1 - 0.003 18.0 0.5 0.003 18.0 0.3 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.18 GAM27769.1 - 0.0036 17.0 0.0 0.0067 16.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM27769.1 - 0.0043 16.1 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 GAM27769.1 - 0.07 12.6 0.2 0.31 10.5 0.1 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase Ank_2 PF12796.2 GAM27770.1 - 1.8e-19 69.8 0.1 5e-10 39.5 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM27770.1 - 1.2e-12 46.7 3.9 0.039 14.1 0.0 7.1 7 1 1 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 GAM27770.1 - 3.7e-12 46.4 0.5 4.5e-05 23.8 0.0 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM27770.1 - 6.3e-09 35.7 3.5 0.2 11.9 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM27770.1 - 2.1e-07 30.4 0.2 0.25 11.2 0.0 5.7 4 1 1 5 5 5 3 Ankyrin repeat McrBC PF10117.4 GAM27770.1 - 0.045 12.6 0.1 0.089 11.6 0.1 1.5 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component DUF1280 PF06918.9 GAM27771.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) Ras PF00071.17 GAM27772.1 - 2.9e-54 182.8 0.0 3.8e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM27772.1 - 1.6e-17 64.0 0.1 3.6e-17 62.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM27772.1 - 4.1e-09 35.9 0.0 4.9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM27772.1 - 5.5e-06 25.9 0.0 9.5e-05 21.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM27772.1 - 6.6e-05 22.8 0.0 9.2e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM27772.1 - 0.00057 19.2 0.0 0.0029 16.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 GAM27772.1 - 0.042 13.0 0.0 0.067 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 GAM27772.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain PDEase_I PF00233.14 GAM27773.1 - 2.3e-65 220.6 4.6 3.5e-65 220.0 3.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 GAM27773.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 HD domain CDO_I PF05995.7 GAM27774.1 - 0.00022 20.4 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 GAM27774.1 - 0.0045 16.3 0.5 0.014 14.7 0.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) ABC-3 PF00950.12 GAM27774.1 - 0.095 11.9 0.3 1 8.6 0.5 2.0 2 0 0 2 2 2 0 ABC 3 transport family LIM PF00412.17 GAM27775.1 - 6.2e-13 48.6 7.8 7.1e-13 48.4 5.4 1.1 1 0 0 1 1 1 1 LIM domain DUF329 PF03884.9 GAM27775.1 - 0.35 10.4 7.8 1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF329) YdjO PF14169.1 GAM27775.1 - 1.4 8.4 0.0 1.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-B_box PF00643.19 GAM27775.1 - 2.3 8.1 11.3 7.4 6.5 5.7 2.6 2 1 1 3 3 3 0 B-box zinc finger zf-C3HC4_3 PF13920.1 GAM27775.1 - 5.1 6.8 11.5 3.5 7.3 0.0 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-dskA_traR PF01258.12 GAM27775.1 - 5.4 6.8 7.8 4.6 7.0 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Tmemb_14 PF03647.8 GAM27776.1 - 0.0035 17.6 9.4 0.0046 17.3 6.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C PYST-C1 PF09690.5 GAM27777.1 - 0.025 14.2 3.6 0.025 14.2 2.5 2.6 3 0 0 3 3 3 0 Plasmodium yoelii subtelomeric region (PYST-C1) DUF3947 PF13135.1 GAM27777.1 - 1.4 9.2 16.5 0.049 13.8 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) MRP-S33 PF08293.6 GAM27778.1 - 4e-07 29.9 0.2 5.8e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SNARE PF05739.14 GAM27779.1 - 5.9e-06 25.8 3.4 5.9e-06 25.8 2.4 1.8 2 1 0 2 2 2 1 SNARE domain DUF443 PF04276.7 GAM27779.1 - 0.0096 15.3 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF443) Pex24p PF06398.6 GAM27779.1 - 0.014 14.1 0.2 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF1664 PF07889.7 GAM27779.1 - 0.17 11.7 0.9 0.24 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_S64 PF08192.6 GAM27779.1 - 0.22 9.8 3.3 0.26 9.5 2.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 SlyX PF04102.7 GAM27779.1 - 0.33 11.3 2.1 0.32 11.3 0.3 1.8 1 1 1 2 2 2 0 SlyX Synaptobrevin PF00957.16 GAM27779.1 - 0.41 10.2 6.0 1.4 8.5 1.9 2.3 1 1 1 2 2 2 0 Synaptobrevin Sec20 PF03908.8 GAM27779.1 - 0.59 9.8 3.2 0.97 9.1 1.4 1.9 1 1 1 2 2 2 0 Sec20 Tweety PF04906.8 GAM27779.1 - 1.4 7.2 6.8 0.13 10.6 1.0 1.7 1 1 1 2 2 2 0 Tweety DUF843 PF05814.6 GAM27779.1 - 7.8 6.3 7.6 18 5.2 5.2 1.7 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF912 PF06024.7 GAM27779.1 - 9.7 6.3 8.3 92 3.1 5.8 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ank_3 PF13606.1 GAM27781.1 - 0.0005 20.0 0.5 0.32 11.3 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.2 GAM27781.1 - 0.00076 19.7 0.0 0.0047 17.2 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM27781.1 - 0.014 15.9 0.1 0.12 12.9 0.0 2.6 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM27781.1 - 0.072 12.9 0.1 0.65 9.9 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat ERG2_Sigma1R PF04622.7 GAM27782.1 - 2.6e-13 49.7 0.5 1e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 ERG2 and Sigma1 receptor like protein DUF4477 PF14780.1 GAM27783.1 - 1e-09 38.0 0.2 1e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) LMBR1 PF04791.11 GAM27783.1 - 0.017 13.7 3.1 0.019 13.5 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.13 GAM27783.1 - 0.047 11.9 1.1 0.049 11.9 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein AvrE PF11725.3 GAM27783.1 - 2.3 5.1 21.9 2.9 4.7 15.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor TFIIA PF03153.8 GAM27783.1 - 9.5 5.9 34.2 12 5.6 23.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRF-TF PF00319.13 GAM27784.1 - 1.1e-23 82.2 0.1 1.7e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Spt20 PF12090.3 GAM27784.1 - 0.0021 17.4 4.9 0.0028 17.0 3.4 1.3 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.8 GAM27784.1 - 0.0024 17.8 20.5 0.0042 17.0 14.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 GAM27784.1 - 0.23 11.2 12.4 0.35 10.6 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 GAM27784.1 - 0.27 10.2 13.1 0.39 9.7 9.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 GAM27784.1 - 0.45 8.6 31.1 0.67 8.1 21.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 GAM27784.1 - 0.46 8.1 4.2 0.64 7.7 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BAF1_ABF1 PF04684.8 GAM27784.1 - 0.52 9.0 20.0 0.71 8.6 13.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Tim54 PF11711.3 GAM27784.1 - 3.7 6.0 8.2 6.1 5.3 5.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LIM_bind PF01803.11 GAM27784.1 - 3.8 6.5 12.7 7.5 5.5 8.8 1.4 1 0 0 1 1 1 0 LIM-domain binding protein Suf PF05843.9 GAM27784.1 - 4.2 7.0 23.3 5.5 6.6 16.1 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 GAM27784.1 - 5 5.7 5.8 6.5 5.3 4.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 GAM27784.1 - 6.9 4.2 26.2 8.9 3.8 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glucokinase PF02685.11 GAM27785.1 - 4.4e-20 71.7 0.0 6.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Glucokinase ROK PF00480.15 GAM27785.1 - 0.00011 22.0 0.1 0.0083 15.9 0.0 2.4 2 0 0 2 2 2 1 ROK family FGGY_N PF00370.16 GAM27785.1 - 0.012 14.9 0.1 0.027 13.8 0.0 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Hydant_A_N PF05378.8 GAM27785.1 - 0.038 13.5 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF2039 PF10217.4 GAM27786.1 - 1e-24 86.3 14.9 1e-24 86.3 10.3 2.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2039) Nop14 PF04147.7 GAM27786.1 - 0.00017 19.7 32.1 0.00019 19.5 22.3 1.2 1 0 0 1 1 1 1 Nop14-like family Paired_CXXCH_1 PF09699.5 GAM27786.1 - 0.0041 16.6 0.5 0.0041 16.6 0.4 2.8 2 1 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) CDC45 PF02724.9 GAM27786.1 - 0.69 7.8 28.7 0.97 7.3 19.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 GAM27786.1 - 0.83 7.8 12.1 0.87 7.7 8.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Daxx PF03344.10 GAM27786.1 - 1.3 7.4 39.2 1.6 7.1 27.2 1.1 1 0 0 1 1 1 0 Daxx Family Rap1-DNA-bind PF09197.5 GAM27786.1 - 3.6 8.1 0.0 3.6 8.1 0.0 4.0 2 1 2 4 4 4 0 Rap1, DNA-binding Cellulase PF00150.13 GAM27787.1 - 2.8e-30 105.4 0.1 4e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 GAM27787.1 - 0.0024 17.0 0.9 0.004 16.3 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase MFS_1 PF07690.11 GAM27788.1 - 1.9e-29 102.4 34.4 1.5e-15 56.8 15.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM27788.1 - 7.5e-06 24.7 35.9 7.1e-05 21.5 7.6 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 GAM27788.1 - 0.0013 17.2 31.9 0.0043 15.5 21.9 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein DUF464 PF04327.7 GAM27788.1 - 0.029 14.5 0.2 6.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF464) Ank_2 PF12796.2 GAM27790.1 - 4.1e-49 164.8 34.6 2.5e-10 40.5 0.2 7.4 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM27790.1 - 4.1e-46 153.9 26.2 0.00026 21.1 0.0 14.2 3 3 11 14 14 14 14 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM27790.1 - 2.7e-39 132.8 17.4 4.6e-05 23.8 0.1 9.9 6 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27790.1 - 1.5e-26 89.8 14.7 0.38 11.1 0.0 15.0 8 3 7 15 15 15 7 Ankyrin repeat Ank PF00023.25 GAM27790.1 - 2.5e-24 83.7 20.7 0.65 9.9 0.0 14.9 15 1 1 16 16 16 7 Ankyrin repeat DUF1242 PF06842.7 GAM27790.1 - 1.5e-14 53.2 1.5 4.3e-14 51.7 1.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Rbsn PF11464.3 GAM27790.1 - 0.00079 18.9 0.0 1.4e+02 2.1 0.0 7.1 9 0 0 9 9 9 0 Rabenosyn Rab binding domain DUF2462 PF09495.5 GAM27790.1 - 0.0025 18.5 0.1 11 6.8 0.0 5.7 6 2 2 8 8 8 1 Protein of unknown function (DUF2462) LSM PF01423.17 GAM27791.1 - 3.4e-11 42.5 0.1 7.1e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 LSM domain TFIIA PF03153.8 GAM27791.1 - 0.0056 16.6 8.2 0.0061 16.5 5.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.8 GAM27791.1 - 0.063 12.6 2.3 18 4.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.4 GAM27791.1 - 0.88 7.7 21.9 1.1 7.4 15.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 GAM27791.1 - 4.7 7.2 19.8 11 6.1 12.2 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 GAM27791.1 - 7 5.9 22.9 11 5.3 15.9 1.3 1 0 0 1 1 1 0 Vta1 like NUDIX PF00293.23 GAM27792.1 - 0.00022 20.8 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain RhoGAP PF00620.22 GAM27793.1 - 2.7e-34 118.0 0.0 5.5e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Ycf1 PF05758.7 GAM27793.1 - 0.00047 18.0 3.4 0.00071 17.4 2.4 1.3 1 0 0 1 1 1 1 Ycf1 FTO_NTD PF12933.2 GAM27793.1 - 0.33 10.0 2.4 0.62 9.1 1.7 1.3 1 0 0 1 1 1 0 FTO catalytic domain RR_TM4-6 PF06459.7 GAM27793.1 - 0.51 10.1 15.0 1.2 8.9 10.4 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FNIP PF05725.7 GAM27794.1 - 4e-97 317.9 26.4 4.8e-15 55.2 0.1 9.3 9 0 0 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 GAM27794.1 - 0.00032 20.5 4.3 18 5.3 0.0 6.8 4 2 5 9 9 9 1 Protein of unknown function (DUF1769) CBM_20 PF00686.14 GAM27795.1 - 2.2e-19 68.8 0.0 3.7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain Kin17_mid PF10357.4 GAM27796.1 - 5.1e-46 155.4 2.8 5.1e-46 155.4 1.9 2.4 2 1 1 3 3 3 1 Domain of Kin17 curved DNA-binding protein KOW PF00467.24 GAM27796.1 - 6.9e-05 22.4 0.0 0.00026 20.5 0.0 2.1 1 0 0 1 1 1 1 KOW motif MMtag PF10159.4 GAM27796.1 - 1.2 9.2 6.0 0.57 10.2 0.6 2.4 2 0 0 2 2 2 0 Kinase phosphorylation protein UPRTase PF14681.1 GAM27797.1 - 1.9e-62 210.1 0.0 3.2e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 GAM27797.1 - 5e-54 182.8 0.2 8.9e-54 182.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 GAM27797.1 - 2.1e-07 31.7 0.1 4.9e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM27797.1 - 3e-07 30.7 0.1 3e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Pribosyltran PF00156.22 GAM27797.1 - 0.0035 17.0 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain CoaE PF01121.15 GAM27797.1 - 0.0042 16.4 0.3 1.5 8.1 0.2 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase MobB PF03205.9 GAM27797.1 - 0.0062 16.2 0.7 0.034 13.8 0.1 2.4 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 GAM27797.1 - 0.014 15.2 0.1 0.046 13.5 0.0 1.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 GAM27797.1 - 0.031 13.3 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Corona_M PF01635.13 GAM27797.1 - 0.14 11.0 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Pep_deformylase PF01327.16 GAM27798.1 - 3.7e-47 159.6 0.0 4.8e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase FNIP PF05725.7 GAM27799.1 - 9.8e-52 172.6 30.0 3.3e-14 52.5 0.5 8.5 7 1 2 9 9 9 8 FNIP Repeat Herpes_BLRF2 PF05812.7 GAM27799.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein LRR_4 PF12799.2 GAM27799.1 - 0.24 11.0 10.6 1.7 8.3 0.5 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM27799.1 - 0.33 11.1 9.6 12 6.3 0.7 5.8 6 1 1 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 GAM27799.1 - 4 8.0 10.7 17 6.1 0.1 5.6 7 0 0 7 7 7 0 Leucine rich repeat Coiled PF05710.7 GAM27800.1 - 0.1 13.0 8.0 0.2 12.1 5.6 1.5 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.7 GAM27801.1 - 0.00076 19.8 7.6 0.001 19.5 5.2 1.2 1 0 0 1 1 1 1 Coiled coil FNIP PF05725.7 GAM27802.1 - 1.9e-31 107.7 4.5 1.9e-14 53.2 0.0 3.0 2 1 1 3 3 3 3 FNIP Repeat Tecti-min-caps PF09300.5 GAM27802.1 - 0.058 13.1 0.1 21 4.9 0.0 3.4 3 1 1 4 4 4 0 Tectiviridae, minor capsid Man-6-P_recep PF02157.10 GAM27804.1 - 0.0026 16.8 2.7 0.008 15.2 1.9 1.8 1 1 0 1 1 1 1 Mannose-6-phosphate receptor VSP PF03302.8 GAM27804.1 - 0.0059 15.2 1.0 0.0099 14.5 0.2 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF2034 PF10356.4 GAM27804.1 - 0.027 13.6 0.2 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) Sec1 PF00995.18 GAM27805.1 - 2.1e-117 393.1 0.0 2.4e-117 392.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DPBB_1 PF03330.13 GAM27807.1 - 1.3e-16 60.3 0.7 3.8e-16 58.8 0.0 2.2 3 0 0 3 3 3 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 GAM27807.1 - 7.2e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Cerato-platanin Keratin_matx PF04579.7 GAM27807.1 - 0.0061 16.8 2.8 0.015 15.5 1.6 2.0 1 1 1 2 2 2 1 Keratin, high-sulphur matrix protein Barwin PF00967.12 GAM27807.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Barwin family PCMT PF01135.14 GAM27808.1 - 2.2e-64 216.8 0.0 3e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 GAM27808.1 - 2.4e-06 28.0 0.0 4.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM27808.1 - 4.7e-06 26.2 0.3 8.7e-06 25.3 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM27808.1 - 0.00051 19.4 0.2 0.0015 17.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_3 PF01596.12 GAM27808.1 - 0.00084 18.4 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase FtsJ PF01728.14 GAM27808.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 GAM27808.1 - 0.0061 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 GAM27808.1 - 0.0085 15.2 0.2 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.5 GAM27808.1 - 0.0086 15.5 0.0 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.7 GAM27808.1 - 0.0097 16.3 0.0 0.031 14.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM27808.1 - 0.019 15.3 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 GAM27808.1 - 0.048 13.3 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 GAM27808.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM27808.1 - 0.12 11.5 0.1 0.2 10.7 0.1 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1805 PF08827.6 GAM27808.1 - 0.12 12.1 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Fibrillarin PF01269.12 GAM27808.1 - 0.24 10.3 1.2 1.4 7.7 0.2 2.2 1 1 1 2 2 2 0 Fibrillarin Exo_endo_phos PF03372.18 GAM27809.1 - 3.4e-14 53.3 0.6 4e-14 53.1 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAM27809.1 - 0.13 11.8 3.5 0.89 9.1 1.5 3.1 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Atg8 PF02991.11 GAM27810.1 - 5.3e-43 145.2 0.3 6.3e-43 144.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 GAM27810.1 - 1.7e-07 31.3 0.0 2.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LCE PF14672.1 GAM27811.1 - 2.3 8.7 7.9 4.6 7.7 5.5 1.4 1 0 0 1 1 1 0 Late cornified envelope Kelch_1 PF01344.20 GAM27812.1 - 3.2e-09 36.2 2.2 0.016 14.7 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM27812.1 - 1.4e-07 31.4 1.2 0.022 14.9 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM27812.1 - 6e-07 29.3 0.9 0.46 10.7 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM27812.1 - 2.9e-06 26.9 10.3 0.069 12.9 0.0 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM27812.1 - 0.0045 16.9 3.3 3.9 7.5 0.0 4.0 5 0 0 5 5 5 2 Kelch motif Exo_endo_phos PF03372.18 GAM27813.1 - 5.2e-08 33.1 0.3 6.5e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cofilin_ADF PF00241.15 GAM27814.1 - 1.7e-30 105.4 0.2 2e-30 105.2 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4476 PF14771.1 GAM27816.1 - 8.8e-14 51.3 1.9 1e-13 51.1 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) PcfK PF14058.1 GAM27816.1 - 0.026 14.6 0.4 0.031 14.4 0.3 1.2 1 0 0 1 1 1 0 PcfK-like protein Syd PF07348.7 GAM27816.1 - 0.065 12.5 0.2 0.093 12.0 0.1 1.4 1 1 0 1 1 1 0 Syd protein (SUKH-2) Syntaxin_2 PF14523.1 GAM27816.1 - 0.08 12.9 0.8 0.13 12.2 0.6 1.4 1 1 0 1 1 1 0 Syntaxin-like protein FragX_IP PF05994.6 GAM27817.1 - 4.7e-262 871.4 11.0 4.7e-262 871.4 7.6 1.8 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.7 GAM27817.1 - 2.6e-14 53.0 5.7 5.4e-14 52.0 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WXG100 PF06013.7 GAM27817.1 - 0.055 13.4 2.4 7.8 6.5 0.0 4.1 4 0 0 4 4 4 0 Proteins of 100 residues with WXG EGF_2 PF07974.8 GAM27819.1 - 0.011 15.8 14.4 0.022 14.8 10.0 1.5 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM27819.1 - 0.11 12.4 9.9 0.24 11.3 6.8 1.6 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.2 GAM27819.1 - 0.23 11.6 6.1 0.56 10.3 4.2 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF RVT_1 PF00078.22 GAM27822.1 - 5.6e-21 74.8 0.4 1.2e-20 73.8 0.3 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 GAM27822.1 - 1e-19 70.8 0.1 4.5e-19 68.7 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.5 GAM27822.1 - 0.0014 17.9 0.7 0.0036 16.6 0.5 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger MORN PF02493.15 GAM27824.1 - 2.3e-35 118.2 58.0 5.8e-07 28.8 1.5 12.6 11 1 2 13 13 13 10 MORN repeat FNIP PF05725.7 GAM27826.1 - 2.3e-46 155.4 28.5 6.4e-07 29.2 0.2 10.0 6 3 4 10 10 10 10 FNIP Repeat bZIP_1 PF00170.16 GAM27826.1 - 0.00097 19.0 3.2 0.0019 18.1 2.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor BLOC1_2 PF10046.4 GAM27826.1 - 0.0011 19.0 0.7 0.0025 17.9 0.5 1.5 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 GAM27826.1 - 0.0057 16.9 0.3 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) HALZ PF02183.13 GAM27826.1 - 0.0064 16.1 4.2 0.015 15.0 2.9 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 GAM27826.1 - 0.0083 16.3 0.7 0.02 15.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Cep57_MT_bd PF06657.8 GAM27826.1 - 0.018 14.9 0.5 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.10 GAM27826.1 - 0.035 13.5 0.5 0.067 12.6 0.3 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 GAM27826.1 - 0.13 12.0 4.2 0.29 10.9 2.9 1.6 1 0 0 1 1 1 0 Basic region leucine zipper FlaC_arch PF05377.6 GAM27826.1 - 0.17 11.8 1.6 0.35 10.7 1.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Tir_receptor_C PF07489.6 GAM27826.1 - 1.3 8.7 4.3 2.6 7.7 3.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus UPF0014 PF03649.8 GAM27827.1 - 0.064 12.3 3.2 0.076 12.1 2.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) Coiled PF05710.7 GAM27828.1 - 0.13 12.7 11.3 0.25 11.8 7.8 1.5 1 1 0 1 1 1 0 Coiled coil Pkinase_Tyr PF07714.12 GAM27829.1 - 7.9e-52 175.8 0.0 1.3e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM27829.1 - 7.7e-47 159.6 0.0 1.8e-46 158.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.1 GAM27829.1 - 6.5e-25 86.6 26.8 1.7e-09 37.2 0.9 6.2 5 1 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 GAM27829.1 - 2.3e-24 84.5 38.1 4.1e-09 35.8 1.3 8.2 6 2 2 8 8 8 6 Leucine Rich repeats (2 copies) RhoGEF PF00621.15 GAM27829.1 - 7.6e-14 51.9 5.6 5.3e-13 49.2 3.4 2.6 1 1 0 2 2 2 1 RhoGEF domain LRR_1 PF00560.28 GAM27829.1 - 1.1e-13 49.1 33.1 0.25 11.4 0.0 11.8 12 0 0 12 12 12 5 Leucine Rich Repeat Ras PF00071.17 GAM27829.1 - 7.7e-10 38.3 0.3 8e-08 31.8 0.0 2.6 2 0 0 2 2 2 1 Ras family LRR_7 PF13504.1 GAM27829.1 - 3.7e-09 35.3 17.9 0.53 10.7 0.1 10.0 9 0 0 9 9 9 3 Leucine rich repeat Miro PF08477.8 GAM27829.1 - 2.9e-08 34.2 0.0 1e-07 32.4 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein LRR_6 PF13516.1 GAM27829.1 - 0.00013 21.6 27.7 0.9 9.8 0.4 9.3 10 0 0 10 10 10 2 Leucine Rich repeat Complex1_LYR PF05347.10 GAM27830.1 - 0.00024 20.8 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM27830.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF434 PF04256.7 GAM27830.1 - 0.04 13.2 0.1 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Herpes_LMP1 PF05297.6 GAM27831.1 - 5.1 5.9 10.3 14 4.4 7.1 1.8 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FNIP PF05725.7 GAM27832.1 - 1.6e-41 139.9 13.4 1.2e-11 44.3 0.0 7.4 5 1 4 9 9 9 8 FNIP Repeat FtsJ PF01728.14 GAM27833.1 - 4.7e-60 202.6 0.0 6.5e-60 202.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 GAM27833.1 - 0.013 16.0 0.0 0.074 13.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 GAM27833.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 GAM27833.1 - 0.1 12.1 0.0 0.52 9.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PARG_cat PF05028.9 GAM27835.1 - 2.2e-127 425.0 0.0 2.9e-127 424.5 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) SWI-SNF_Ssr4 PF08549.5 GAM27836.1 - 0.068 11.4 0.1 0.071 11.4 0.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) NUMOD3 PF07460.6 GAM27837.1 - 0.022 14.6 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Sdh_cyt PF01127.17 GAM27837.1 - 0.11 12.3 1.0 0.46 10.3 0.2 2.3 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FNIP PF05725.7 GAM27838.1 - 0.002 18.0 2.4 0.25 11.3 0.1 2.7 2 1 0 2 2 2 2 FNIP Repeat FNIP PF05725.7 GAM27839.1 - 2.1e-81 267.6 3.1 2.9e-13 49.5 0.0 9.2 6 2 0 9 9 9 8 FNIP Repeat Phosducin PF02114.11 GAM27840.1 - 0.028 13.1 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin HMG_box PF00505.14 GAM27841.1 - 2.7e-19 69.1 0.7 2.7e-19 69.1 0.5 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 GAM27841.1 - 1.1e-12 48.1 0.9 1.1e-12 48.1 0.6 2.1 2 0 0 2 2 2 1 HMG-box domain MCPVI PF02993.9 GAM27841.1 - 0.0069 16.5 14.4 0.0092 16.1 10.0 1.3 1 0 0 1 1 1 1 Minor capsid protein VI Ycf1 PF05758.7 GAM27841.1 - 0.0099 13.6 4.7 0.0093 13.7 3.3 1.0 1 0 0 1 1 1 1 Ycf1 Borrelia_P83 PF05262.6 GAM27841.1 - 0.013 13.7 9.3 0.016 13.4 6.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spore_coat_CotO PF14153.1 GAM27841.1 - 0.018 14.5 14.0 0.021 14.2 9.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Med15 PF09606.5 GAM27841.1 - 0.019 13.2 36.8 0.027 12.6 25.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CHDNT PF08073.7 GAM27841.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain PSI_PsaF PF02507.10 GAM27841.1 - 0.12 11.8 2.8 0.18 11.3 2.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III LMBR1 PF04791.11 GAM27841.1 - 0.37 9.3 1.2 0.39 9.2 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.4 GAM27841.1 - 0.59 8.3 14.8 0.68 8.1 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein YABBY PF04690.8 GAM27841.1 - 0.61 10.3 16.8 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 YABBY protein APG6 PF04111.7 GAM27841.1 - 0.68 8.9 15.9 0.89 8.5 11.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Hid1 PF12722.2 GAM27841.1 - 1.1 6.8 13.2 1.2 6.6 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_23 PF13476.1 GAM27841.1 - 1.3 9.3 13.2 1.6 8.9 9.2 1.1 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 GAM27841.1 - 1.6 6.8 44.7 1.9 6.6 31.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TraG_N PF07916.6 GAM27841.1 - 1.8 6.8 5.1 2.4 6.4 3.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AUX_IAA PF02309.11 GAM27841.1 - 2.8 7.6 10.0 4.6 6.9 6.9 1.3 1 0 0 1 1 1 0 AUX/IAA family BTV_NS2 PF04514.7 GAM27841.1 - 4.1 6.2 10.5 5.1 5.8 7.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 GAM27841.1 - 4.7 6.7 24.8 6.7 6.2 17.2 1.1 1 0 0 1 1 1 0 IncA protein RR_TM4-6 PF06459.7 GAM27841.1 - 6.1 6.6 15.2 9.1 6.0 10.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF853 PF05872.7 GAM27841.1 - 8.4 4.6 10.5 11 4.1 7.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Presenilin PF01080.12 GAM27841.1 - 9.3 4.9 7.5 13 4.5 5.2 1.2 1 0 0 1 1 1 0 Presenilin CDK5_activator PF03261.10 GAM27841.1 - 9.6 5.4 13.1 12 5.0 9.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Myotub-related PF06602.9 GAM27843.1 - 1.6e-134 448.1 0.0 1.6e-134 448.1 0.0 2.0 3 0 0 3 3 3 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 GAM27843.1 - 0.011 15.1 0.0 0.027 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM27843.1 - 0.041 14.1 0.2 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family MSA-2c PF12238.3 GAM27843.1 - 0.18 11.4 6.1 0.46 10.1 0.1 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c 3-PAP PF12578.3 GAM27843.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.9 4 0 0 4 4 4 0 Myotubularin-associated protein Oxysterol_BP PF01237.13 GAM27844.1 - 8.9e-106 353.3 0.5 1.4e-105 352.7 0.3 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Med2 PF11214.3 GAM27844.1 - 0.07 13.1 1.1 0.3 11.1 0.6 2.1 2 0 0 2 2 2 0 Mediator complex subunit 2 DUF3275 PF11679.3 GAM27844.1 - 0.38 10.3 8.1 0.97 9.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) IF3_C PF00707.17 GAM27845.1 - 1.1e-06 28.3 0.5 4.4e-06 26.3 0.3 2.1 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 GAM27845.1 - 1.5e-06 28.0 0.4 5.3e-06 26.2 0.3 2.0 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Helicase_C PF00271.26 GAM27847.1 - 5.7e-08 32.5 0.0 1.8e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM27848.1 - 4.1e-21 75.1 0.1 5.4e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 GAM27848.1 - 0.022 14.5 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SIR2 PF02146.12 GAM27849.1 - 7.9e-25 87.6 1.2 5.8e-22 78.2 0.8 2.3 1 1 0 1 1 1 1 Sir2 family MFS_1 PF07690.11 GAM27850.1 - 7.2e-31 107.1 27.7 7.2e-31 107.1 19.2 1.9 1 1 2 3 3 3 1 Major Facilitator Superfamily DUF485 PF04341.7 GAM27850.1 - 0.0025 17.4 7.1 0.28 10.8 0.2 3.6 3 0 0 3 3 3 2 Protein of unknown function, DUF485 MFS_3 PF05977.8 GAM27850.1 - 0.051 11.6 7.7 0.25 9.4 0.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Col_cuticle_N PF01484.12 GAM27850.1 - 4.5 7.0 7.6 2.2 8.0 2.1 2.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain GAGA_bind PF06217.7 GAM27853.1 - 0.0014 18.7 14.0 0.0014 18.7 9.7 1.6 2 0 0 2 2 2 1 GAGA binding protein-like family DUF2457 PF10446.4 GAM27853.1 - 0.0022 16.8 3.3 0.0022 16.8 2.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Hid1 PF12722.2 GAM27853.1 - 0.0061 14.3 15.7 0.0069 14.1 10.9 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein PMSI1 PF15322.1 GAM27853.1 - 0.061 12.4 9.5 0.094 11.7 6.6 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative LMBR1 PF04791.11 GAM27853.1 - 0.12 10.9 3.9 0.15 10.6 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 GAM27853.1 - 0.67 7.9 31.4 0.23 9.4 14.4 2.1 2 0 0 2 2 2 0 CDC45-like protein PAT1 PF09770.4 GAM27853.1 - 0.67 8.1 43.9 0.93 7.6 30.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.1 GAM27853.1 - 2.4 6.5 22.5 1.5 7.2 13.0 2.1 2 0 0 2 2 2 0 Raftlin DUF4638 PF15472.1 GAM27853.1 - 2.4 7.6 16.7 4.7 6.7 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Parvo_coat PF00740.13 GAM27853.1 - 2.7 6.8 24.8 4 6.2 17.2 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4045 PF13254.1 GAM27853.1 - 3.3 6.8 23.0 0.49 9.6 11.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Med15 PF09606.5 GAM27853.1 - 3.4 5.7 53.5 4.3 5.4 37.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2413 PF10310.4 GAM27853.1 - 3.6 6.3 31.8 0.13 11.0 15.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) SprA-related PF12118.3 GAM27853.1 - 4.7 6.4 50.4 0.11 11.8 27.6 2.1 2 0 0 2 2 2 0 SprA-related family Ndc1_Nup PF09531.5 GAM27853.1 - 5.7 5.2 9.6 6.6 5.0 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDK5_activator PF03261.10 GAM27853.1 - 6.3 6.0 14.6 11 5.2 10.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Herpes_UL87 PF03043.9 GAM27853.1 - 6.9 4.9 11.7 9 4.5 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family eIF-3_zeta PF05091.7 GAM27853.1 - 8.1 4.9 23.3 12 4.4 16.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) vATP-synt_E PF01991.13 GAM27856.1 - 0.047 12.9 0.4 0.063 12.5 0.3 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Ribosomal_S20p PF01649.13 GAM27857.1 - 0.053 13.9 1.1 0.069 13.5 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein S20 CDC45 PF02724.9 GAM27858.1 - 0.41 8.6 7.9 0.48 8.4 5.0 1.4 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 GAM27858.1 - 1.1 7.0 13.4 1.4 6.7 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3820 PF12843.2 GAM27859.1 - 0.019 14.5 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) Glyco_hydro_3 PF00933.16 GAM27860.1 - 2.5e-61 207.2 0.0 1.6e-59 201.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM27860.1 - 6.4e-48 163.2 0.1 9.6e-48 162.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM27860.1 - 2.9e-10 39.9 0.0 5.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pkinase_Tyr PF07714.12 GAM27861.1 - 9.9e-43 146.0 0.0 1.4e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM27861.1 - 1.5e-42 145.5 0.0 2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM27861.1 - 2.3e-07 30.5 0.0 6.2e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.9 GAM27861.1 - 0.042 13.4 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain FNIP PF05725.7 GAM27862.1 - 3e-74 244.7 15.9 1.1e-11 44.4 0.1 10.0 7 2 3 11 11 11 9 FNIP Repeat DUF1769 PF08588.5 GAM27862.1 - 5.1e-06 26.3 0.2 17 5.4 0.0 6.7 4 2 3 7 7 7 2 Protein of unknown function (DUF1769) DUF2208 PF09973.4 GAM27863.1 - 0.017 14.3 0.2 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF1761 PF08570.5 GAM27863.1 - 0.042 13.8 0.5 0.065 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF2207 PF09972.4 GAM27863.1 - 0.18 10.3 4.1 0.25 9.8 2.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1014 PF06244.7 GAM27864.1 - 2e-25 89.3 38.7 4e-21 75.4 26.8 3.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) TMEM247 PF15444.1 GAM27864.1 - 0.42 10.4 0.1 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 2OG-FeII_Oxy_3 PF13640.1 GAM27865.1 - 4.7e-10 39.8 0.1 9.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 GAM27865.1 - 3.4e-05 22.8 0.0 4.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy_4 PF13661.1 GAM27865.1 - 0.0032 17.0 0.1 0.0069 16.0 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cas_csx3 PF09620.5 GAM27865.1 - 0.02 14.6 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Neurochondrin PF05536.6 GAM27868.1 - 1e-24 86.8 5.1 8.8e-19 67.2 2.5 2.2 1 1 1 2 2 2 2 Neurochondrin IBR PF01485.16 GAM27869.1 - 4.3e-19 68.1 25.6 7.9e-11 41.6 5.4 4.5 3 1 1 4 4 4 2 IBR domain zf-C3HC4_2 PF13923.1 GAM27869.1 - 4.2e-05 23.4 8.4 4.2e-05 23.4 5.8 5.0 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM27869.1 - 4.7e-05 23.1 7.4 4.7e-05 23.1 5.2 4.1 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM27869.1 - 0.00067 19.2 39.9 0.0076 15.9 4.5 4.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM27869.1 - 0.0065 16.1 7.9 0.0065 16.1 5.5 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Arm PF00514.18 GAM27870.1 - 8e-82 266.5 11.7 4e-12 45.4 0.1 8.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAM27870.1 - 3.9e-22 78.0 0.2 4.5e-06 26.9 0.0 4.9 4 0 0 4 4 4 4 HEAT-like repeat HEAT_2 PF13646.1 GAM27870.1 - 8.6e-21 74.0 0.2 1.6e-06 28.2 0.0 5.3 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 GAM27870.1 - 2.7e-12 45.6 1.0 0.002 18.0 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat IBB PF01749.15 GAM27870.1 - 2.7e-09 37.0 10.2 2.7e-09 37.0 7.1 2.1 2 1 0 2 2 2 1 Importin beta binding domain V-ATPase_H_C PF11698.3 GAM27870.1 - 4.5e-08 33.0 1.0 0.75 9.7 0.0 4.3 4 0 0 4 4 4 3 V-ATPase subunit H Arm_2 PF04826.8 GAM27870.1 - 8.2e-07 28.3 1.7 0.019 14.0 0.2 3.3 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 GAM27870.1 - 4.8e-05 21.8 0.1 0.00093 17.6 0.1 2.9 1 1 0 1 1 1 1 Adaptin N terminal region RICTOR_V PF14668.1 GAM27870.1 - 0.0023 17.8 3.8 4.5 7.2 0.2 4.5 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 GAM27870.1 - 0.0033 17.7 0.3 1.7 9.3 0.0 4.4 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 GAM27870.1 - 0.033 12.4 1.5 0.12 10.6 0.2 2.2 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 GAM27870.1 - 0.2 10.6 1.8 0.34 9.9 0.0 2.3 2 1 0 2 2 2 0 Mo25-like Atx10homo_assoc PF09759.4 GAM27870.1 - 0.22 11.2 2.8 30 4.4 0.0 3.8 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Trypan_PARP PF05887.6 GAM27871.1 - 0.019 14.7 25.5 0.027 14.2 17.4 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PLRV_ORF5 PF01690.12 GAM27871.1 - 0.2 10.7 23.3 0.25 10.4 16.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2201_N PF13203.1 GAM27871.1 - 1.8 7.6 12.3 1.9 7.5 7.1 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain Mitofilin PF09731.4 GAM27871.1 - 1.8 7.0 22.7 2.2 6.8 15.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.5 GAM27871.1 - 1.9 6.8 10.7 2.3 6.5 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 GAM27871.1 - 2.2 8.0 23.2 4 7.2 16.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 GAM27871.1 - 3 6.9 34.1 3.7 6.6 23.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 GAM27871.1 - 7.1 4.5 17.8 11 3.8 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein G-patch PF01585.18 GAM27872.1 - 1.7e-11 43.7 3.3 4.4e-11 42.3 2.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM27872.1 - 7.7e-06 25.6 0.2 7.7e-06 25.6 0.1 2.3 2 1 0 2 2 2 1 DExH-box splicing factor binding site CWC25 PF12542.3 GAM27872.1 - 0.47 10.9 10.2 0.87 10.0 7.1 1.4 1 1 0 1 1 1 0 Pre-mRNA splicing factor Ank_2 PF12796.2 GAM27873.1 - 4.5e-31 107.0 4.1 1.3e-10 41.4 0.0 4.4 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM27873.1 - 1.1e-24 86.2 0.5 7.9e-07 29.4 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM27873.1 - 4.7e-22 77.5 0.9 1.7e-05 24.8 0.0 6.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM27873.1 - 3.1e-21 73.3 1.2 0.0059 16.7 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.25 GAM27873.1 - 3.5e-20 70.7 8.9 6.7e-05 22.4 0.1 7.9 8 0 0 8 8 8 5 Ankyrin repeat AAA PF00004.24 GAM27874.1 - 5e-39 133.5 0.0 1.1e-38 132.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 GAM27874.1 - 7.3e-29 99.4 0.0 1.7e-27 95.0 0.1 2.9 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 GAM27874.1 - 5.1e-19 67.9 8.0 5.1e-19 67.9 5.5 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 GAM27874.1 - 2.6e-06 27.6 0.6 0.00079 19.5 0.4 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM27874.1 - 3.4e-06 26.2 0.0 7.5e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 GAM27874.1 - 2.9e-05 24.8 0.0 0.0001 23.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 GAM27874.1 - 5.7e-05 22.1 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 GAM27874.1 - 8.4e-05 21.4 0.0 0.00023 20.0 0.0 1.6 1 1 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 GAM27874.1 - 9.2e-05 21.9 0.0 0.00028 20.3 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 GAM27874.1 - 0.00012 22.0 0.5 0.00061 19.8 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 GAM27874.1 - 0.00014 21.8 0.1 0.00068 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 GAM27874.1 - 0.00017 21.7 0.0 0.0006 19.9 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 GAM27874.1 - 0.00023 20.9 0.0 0.0006 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 GAM27874.1 - 0.0003 20.6 0.2 0.00089 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 GAM27874.1 - 0.00054 19.4 0.2 0.073 12.4 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 GAM27874.1 - 0.00088 19.1 0.1 0.0038 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 GAM27874.1 - 0.0011 18.6 0.0 0.31 10.6 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 GAM27874.1 - 0.0018 18.5 0.2 0.0074 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 GAM27874.1 - 0.0077 15.3 0.1 0.088 11.8 0.1 2.3 1 1 0 1 1 1 1 Zeta toxin Viral_helicase1 PF01443.13 GAM27874.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 GAM27874.1 - 0.018 14.7 5.1 0.045 13.4 0.1 2.9 2 1 0 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 GAM27874.1 - 0.021 14.0 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 GAM27874.1 - 0.028 13.2 0.0 0.056 12.3 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 GAM27874.1 - 0.029 13.4 0.3 6.2 5.8 0.0 2.4 1 1 1 2 2 2 0 KaiC Use1 PF09753.4 GAM27874.1 - 0.029 13.8 3.0 0.14 11.5 1.2 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 AAA_19 PF13245.1 GAM27874.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 GAM27874.1 - 0.036 12.9 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 GAM27874.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAM27874.1 - 0.042 14.1 0.3 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.11 GAM27874.1 - 0.043 13.0 0.0 0.15 11.2 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 GAM27874.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Torsin PPV_E1_C PF00519.12 GAM27874.1 - 0.05 12.2 0.2 0.21 10.1 0.0 1.8 2 0 0 2 2 2 0 Papillomavirus helicase Zot PF05707.7 GAM27874.1 - 0.056 12.9 0.5 2.2 7.7 0.0 2.6 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) DUF2962 PF11176.3 GAM27874.1 - 0.056 13.0 6.2 0.066 12.7 2.7 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF2962) KAP_NTPase PF07693.9 GAM27874.1 - 0.072 12.0 0.1 5.5 5.8 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain CPT PF07931.7 GAM27874.1 - 0.095 12.3 0.0 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.10 GAM27874.1 - 0.1 12.4 1.2 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 GAM27874.1 - 0.24 10.9 6.7 0.096 12.2 0.4 2.5 2 1 0 2 2 2 0 AAA domain TP53IP5 PF15331.1 GAM27874.1 - 1.7 8.5 4.9 4.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 WD40 PF00400.27 GAM27875.1 - 9.1e-57 187.0 37.2 2.2e-10 39.9 0.5 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 GAM27875.1 - 4e-11 41.7 20.2 0.098 10.7 0.0 6.2 2 1 3 6 6 6 6 Nucleoporin Nup120/160 F-box-like PF12937.2 GAM27875.1 - 2.3e-09 36.8 0.3 6.2e-09 35.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 GAM27875.1 - 7.7e-07 28.6 1.0 1.6e-06 27.5 0.7 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 GAM27875.1 - 1.6e-05 24.4 1.0 0.0048 16.4 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain Leu_zip PF15294.1 GAM27875.1 - 0.0035 16.4 1.6 0.0058 15.7 1.1 1.2 1 0 0 1 1 1 1 Leucine zipper PQQ_3 PF13570.1 GAM27875.1 - 0.063 13.5 1.4 68 3.9 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain DUF724 PF05266.9 GAM27875.1 - 0.2 11.2 1.4 0.33 10.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AMP-binding PF00501.23 GAM27876.1 - 2.1e-91 306.3 0.0 2.7e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EF1_GNE PF00736.14 GAM27877.1 - 0.092 12.4 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain zf-RING_2 PF13639.1 GAM27878.1 - 2.2e-11 43.3 4.2 4.6e-11 42.3 2.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM27878.1 - 3.8e-07 30.1 2.0 8.9e-07 28.9 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM27878.1 - 7.8e-07 29.0 4.9 1.7e-06 27.9 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 GAM27878.1 - 7.9e-07 28.8 3.1 2.1e-06 27.4 2.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 GAM27878.1 - 1.9e-06 27.3 3.8 4.5e-06 26.2 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 GAM27878.1 - 3.3e-06 26.8 1.3 1.2e-05 25.0 0.9 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 GAM27878.1 - 0.00031 20.4 2.7 0.0011 18.6 1.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 GAM27878.1 - 0.00034 20.2 2.9 0.00064 19.3 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM27878.1 - 0.00045 19.8 5.1 0.00087 18.9 3.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 GAM27878.1 - 0.0016 18.3 5.1 0.0057 16.5 3.6 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain Rtf2 PF04641.7 GAM27878.1 - 0.0059 15.8 0.2 0.0096 15.1 0.2 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 GAM27878.1 - 0.033 13.7 0.8 0.033 13.7 0.5 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 GAM27878.1 - 0.2 11.2 4.4 0.47 10.0 3.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 GAM27878.1 - 0.23 11.4 3.1 0.46 10.4 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger NAP PF00956.13 GAM27879.1 - 7.5e-26 90.7 5.1 7.5e-26 90.7 3.5 2.8 2 2 0 2 2 2 1 Nucleosome assembly protein (NAP) Mem_trans PF03547.13 GAM27879.1 - 0.7 8.1 4.3 0.92 7.7 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein CEP19 PF14933.1 GAM27879.1 - 1.6 9.0 15.3 2.4 8.4 10.6 1.3 1 0 0 1 1 1 0 CEP19-like protein DUF4544 PF15077.1 GAM27879.1 - 2 7.8 8.4 3.3 7.1 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Ndc1_Nup PF09531.5 GAM27879.1 - 7.8 4.7 12.1 9.2 4.5 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC1 PF03109.11 GAM27880.1 - 1.2e-32 112.3 1.5 3.3e-32 110.9 0.0 2.6 2 0 0 2 2 2 1 ABC1 family LIM PF00412.17 GAM27881.1 - 2e-28 98.2 58.8 9.6e-11 41.5 1.5 5.4 5 1 1 6 6 6 4 LIM domain PTEN_C2 PF10409.4 GAM27881.1 - 7.8e-18 64.4 0.9 2.2e-17 63.0 0.6 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 GAM27881.1 - 1.6e-07 30.9 0.0 3.6e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM27881.1 - 2.5e-05 23.7 0.0 4.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 GAM27881.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM27881.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Ribosomal_L37e PF01907.14 GAM27882.1 - 3.6e-26 90.7 11.5 6.3e-26 89.9 8.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.13 GAM27882.1 - 0.0017 18.0 0.4 0.0025 17.5 0.3 1.3 1 1 0 1 1 1 1 SelR domain DZR PF12773.2 GAM27882.1 - 0.0022 17.7 2.0 0.0032 17.2 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon C1_1 PF00130.17 GAM27882.1 - 0.074 12.7 2.1 0.12 12.1 1.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_6 PF14599.1 GAM27882.1 - 0.41 10.4 2.1 0.65 9.8 1.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon zinc_ribbon_2 PF13240.1 GAM27882.1 - 0.92 9.0 3.6 6.2 6.4 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 GAM27882.1 - 0.98 9.4 5.1 2.2 8.2 0.4 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2082 PF09855.4 GAM27882.1 - 4.2 7.2 5.6 41 4.1 1.5 2.5 1 1 2 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-HYPF PF07503.7 GAM27882.1 - 9.9 5.6 7.5 17 4.9 3.8 2.0 1 1 1 2 2 2 0 HypF finger zf-CCCH PF00642.19 GAM27884.1 - 1.1e-21 75.9 15.5 1e-11 44.2 2.2 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 GAM27884.1 - 0.00035 20.4 6.0 0.15 12.0 0.5 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Usp PF00582.21 GAM27884.1 - 0.18 12.0 0.4 0.5 10.5 0.3 1.7 1 0 0 1 1 1 0 Universal stress protein family Kelch_1 PF01344.20 GAM27885.1 - 1.7e-31 107.5 16.2 1.6e-13 49.9 0.1 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 GAM27885.1 - 2.5e-27 93.8 4.8 1.8e-10 40.5 0.1 4.9 2 1 3 5 5 5 3 Kelch motif BTB_2 PF02214.17 GAM27885.1 - 3.9e-17 62.2 0.0 8.6e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_4 PF13418.1 GAM27885.1 - 5.4e-12 45.2 0.8 0.0002 21.0 0.0 3.9 2 1 1 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM27885.1 - 1.5e-09 37.2 2.8 0.0015 18.1 0.0 5.0 4 1 1 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM27885.1 - 8.5e-09 35.3 2.0 0.33 11.1 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM27885.1 - 2.4e-07 30.5 0.1 0.016 15.1 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Tup_N PF08581.5 GAM27885.1 - 0.015 15.4 2.4 0.03 14.5 1.7 1.4 1 0 0 1 1 1 0 Tup N-terminal DUF972 PF06156.8 GAM27885.1 - 0.034 14.5 0.4 0.065 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IFP_35_N PF07334.8 GAM27885.1 - 0.07 13.1 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RhoGEF PF00621.15 GAM27886.1 - 6.1e-37 127.2 4.5 6.1e-37 127.2 3.1 2.1 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.26 GAM27886.1 - 5.2e-27 94.0 2.6 5.3e-12 45.7 0.0 3.7 3 0 0 3 3 3 2 Calponin homology (CH) domain IQ PF00612.22 GAM27886.1 - 3.8e-05 22.9 2.4 0.00011 21.5 1.7 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 GAM27886.1 - 6.3e-05 22.5 0.8 0.34 10.5 0.0 3.1 3 0 0 3 3 3 2 CAMSAP CH domain PH PF00169.24 GAM27886.1 - 0.0025 18.0 2.6 0.0079 16.3 1.8 1.9 1 0 0 1 1 1 1 PH domain PH_10 PF15411.1 GAM27886.1 - 0.0061 16.7 1.3 0.023 14.8 0.9 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Baculo_PEP_C PF04513.7 GAM27886.1 - 2.6 7.8 13.2 1.8 8.3 0.9 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cyt-b5 PF00173.23 GAM27888.1 - 7.6e-23 80.1 0.3 1e-22 79.7 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MSA-2c PF12238.3 GAM27888.1 - 1.7 8.2 9.3 0.92 9.1 0.8 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Myco_19_kDa PF05481.7 GAM27888.1 - 3.3 7.5 16.2 0.21 11.4 3.0 2.2 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen Herpes_capsid PF06112.6 GAM27888.1 - 6.3 6.8 23.7 2.2 8.2 4.5 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Pheromone PF08015.6 GAM27888.1 - 8.7 7.2 21.7 1.1 10.1 3.0 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF3446 PF11928.3 GAM27888.1 - 9.3 6.5 27.7 0.44 10.7 4.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Tetraspannin PF00335.15 GAM27889.1 - 2.4e-06 27.0 19.1 2.4e-06 27.0 13.2 1.6 1 1 1 2 2 2 1 Tetraspanin family CopD PF05425.8 GAM27889.1 - 0.0023 18.1 0.5 0.014 15.6 0.2 2.0 2 0 0 2 2 2 1 Copper resistance protein D ABC2_membrane_5 PF13346.1 GAM27889.1 - 0.0031 16.8 15.1 0.0031 16.8 10.5 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF308 PF03729.8 GAM27889.1 - 0.026 14.5 5.2 0.026 14.5 3.6 3.2 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) CD20 PF04103.10 GAM27889.1 - 0.053 13.4 16.0 0.08 12.8 11.1 1.3 1 1 0 1 1 1 0 CD20-like family NKAIN PF05640.9 GAM27889.1 - 0.24 10.3 6.5 0.24 10.3 3.7 1.5 1 1 0 1 1 1 0 Na,K-Atpase Interacting protein Sex_peptide PF08138.6 GAM27889.1 - 0.55 10.1 4.2 2.2 8.1 0.0 2.9 2 1 0 2 2 2 0 Sex peptide (SP) family EamA PF00892.15 GAM27889.1 - 1.4 8.9 15.5 42 4.1 9.6 2.4 2 1 0 2 2 2 0 EamA-like transporter family DUF2207 PF09972.4 GAM27889.1 - 2 6.8 14.3 0.09 11.3 4.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.1 GAM27889.1 - 2.2 7.9 16.1 9.2 5.9 11.1 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Arteri_Gl PF00951.13 GAM27889.1 - 4 6.9 9.8 0.23 11.0 2.0 2.1 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein ABC2_membrane_2 PF12679.2 GAM27889.1 - 4.5 6.0 10.8 5.5 5.7 7.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein TRP PF06011.7 GAM27889.1 - 6 5.3 15.9 2.4 6.6 5.7 2.1 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Phage_holin_1 PF04531.8 GAM27889.1 - 6.2 6.9 7.3 1.3 9.1 2.5 1.8 2 0 0 2 2 2 0 Bacteriophage holin DUF805 PF05656.9 GAM27889.1 - 6.3 6.6 14.9 0.25 11.1 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF805) DUF3488 PF11992.3 GAM27889.1 - 9.7 4.7 9.1 19 3.7 4.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) EF-hand_4 PF12763.2 GAM27890.1 - 4.4e-37 125.9 6.2 3.5e-15 55.6 0.0 4.4 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 GAM27890.1 - 2.3e-06 27.6 4.3 0.38 10.9 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 GAM27890.1 - 0.0026 16.9 16.3 5.7 6.4 0.0 5.8 5 1 0 5 5 5 2 EF hand PrcB_C PF14343.1 GAM27890.1 - 0.098 12.3 1.0 0.21 11.3 0.7 1.5 1 0 0 1 1 1 0 PrcB C-terminal EF-hand_8 PF13833.1 GAM27890.1 - 0.13 11.8 2.5 17 5.1 0.0 3.6 3 0 0 3 3 3 0 EF-hand domain pair AAA_13 PF13166.1 GAM27890.1 - 0.2 10.0 28.0 0.33 9.3 19.4 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 GAM27890.1 - 0.95 9.0 47.1 0.98 8.9 14.7 2.4 1 1 1 2 2 2 0 IncA protein Spc7 PF08317.6 GAM27890.1 - 3.4 6.2 38.3 0.27 9.8 16.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 GAM27890.1 - 5.7 6.7 29.6 1.3 8.7 3.7 3.1 1 1 2 3 3 3 0 Laminin Domain II EF-hand_6 PF13405.1 GAM27890.1 - 7.6 6.7 21.4 3.2 7.8 0.0 5.8 6 0 0 6 6 6 0 EF-hand domain Spt5_N PF11942.3 GAM27891.1 - 3.9 8.1 16.3 0.43 11.2 2.2 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal TFIIA PF03153.8 GAM27891.1 - 7.8 6.2 23.3 0.84 9.4 3.9 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 GAM27891.1 - 9.1 5.7 16.1 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin Meth_synt_2 PF01717.13 GAM27892.1 - 1.9e-09 36.9 0.0 5.1e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain PI3_PI4_kinase PF00454.22 GAM27893.1 - 4.1e-51 173.7 0.0 9.3e-51 172.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 GAM27893.1 - 1.2e-32 113.2 0.7 2.7e-32 112.1 0.5 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 GAM27893.1 - 2.3e-19 69.3 1.4 1.7e-18 66.4 0.1 3.5 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.15 GAM27893.1 - 3.1e-14 52.1 0.2 6.7e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 GAM27893.1 - 0.0014 18.4 0.1 6 7.2 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat zf-H2C2 PF09337.5 GAM27894.1 - 0.0022 17.3 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger TPR_2 PF07719.12 GAM27895.1 - 2.6e-05 23.8 3.7 0.035 14.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM27895.1 - 0.0023 17.8 5.8 0.023 14.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM27895.1 - 0.0049 16.4 0.6 4.4 7.0 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 GAM27895.1 - 0.0079 15.7 3.0 5.5 6.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Glyco_hydro_39 PF01229.12 GAM27896.1 - 0.013 13.9 0.0 0.018 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 NapD PF03927.8 GAM27896.1 - 0.16 11.7 0.1 0.45 10.3 0.1 1.7 1 0 0 1 1 1 0 NapD protein DUF3557 PF12078.3 GAM27897.1 - 0.0061 16.2 1.1 0.59 9.8 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3557) DUF92 PF01940.11 GAM27898.1 - 1.9e-71 239.7 2.5 2.7e-71 239.3 1.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Fun_ATP-synt_8 PF05933.8 GAM27898.1 - 5.9 6.9 7.6 3.6 7.6 0.8 3.0 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) HAD PF12710.2 GAM27899.1 - 1.2e-14 54.9 0.0 2.6e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 GAM27899.1 - 2.1e-11 44.6 0.1 7.1e-10 39.6 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM27899.1 - 6.8e-11 41.9 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 GAM27899.1 - 8.3e-09 34.8 0.1 8.3e-09 34.8 0.1 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 GAM27899.1 - 0.0025 17.4 0.5 0.012 15.1 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 GAM27901.1 - 9.6e-18 63.6 1.1 2.9e-08 33.2 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAM27901.1 - 1e-17 62.5 0.3 0.00018 21.1 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 GAM27901.1 - 5.6e-15 54.2 0.5 0.0024 17.4 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 GAM27901.1 - 9e-11 41.4 0.1 0.07 13.7 0.0 4.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 GAM27901.1 - 8.4e-10 38.0 0.4 0.00068 19.6 0.0 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM27901.1 - 2.8e-09 36.7 1.7 0.015 15.2 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM27901.1 - 3.2e-09 35.9 0.2 0.23 11.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM27901.1 - 1.1e-08 35.5 0.0 0.002 18.7 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 GAM27901.1 - 1.3e-06 28.6 0.0 0.0012 19.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM27901.1 - 2e-06 27.1 0.4 0.064 13.0 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM27901.1 - 2.8e-06 27.1 0.0 6.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 GAM27901.1 - 1.9e-05 24.4 2.7 1.9 8.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.1 GAM27901.1 - 0.00012 21.2 0.2 1.6 7.7 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 GAM27901.1 - 0.019 14.3 3.3 0.6 9.4 1.2 3.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Syntaxin_2 PF14523.1 GAM27901.1 - 0.028 14.4 0.6 0.028 14.4 0.4 2.3 2 1 1 3 3 3 0 Syntaxin-like protein Spore_III_AB PF09548.5 GAM27901.1 - 0.072 12.8 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TPR_6 PF13174.1 GAM27901.1 - 0.11 13.0 0.0 17 6.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.17 GAM27902.1 - 1.3e-178 594.8 0.1 1.8e-178 594.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAM27902.1 - 8.2e-26 90.5 0.4 2.2e-16 59.5 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAM27902.1 - 2.9e-25 88.7 0.2 5.3e-25 87.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 GAM27902.1 - 6.2e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 GAM27902.1 - 0.0013 17.9 0.0 0.41 9.7 0.0 3.3 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.9 GAM27902.1 - 0.015 14.9 5.5 0.037 13.6 3.8 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS CHORD PF04968.7 GAM27903.1 - 0.09 13.0 0.2 0.21 11.8 0.2 1.5 1 0 0 1 1 1 0 CHORD DUF3533 PF12051.3 GAM27903.1 - 2.4 6.7 8.0 4.2 5.9 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) LRR_6 PF13516.1 GAM27904.1 - 3.7e-14 51.1 7.7 0.0018 18.1 0.0 5.4 4 1 1 5 5 5 3 Leucine Rich repeat F-box-like PF12937.2 GAM27904.1 - 2.6e-05 23.8 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 GAM27904.1 - 0.0006 19.4 0.1 16 5.9 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.2 GAM27904.1 - 0.00093 18.7 6.9 0.049 13.2 0.1 4.0 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 GAM27904.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Vinculin PF01044.14 GAM27905.1 - 2.7e-41 141.6 50.5 9.3e-22 76.9 16.4 4.8 1 1 3 4 4 4 4 Vinculin family I_LWEQ PF01608.12 GAM27905.1 - 0.00011 22.2 26.4 0.0089 15.9 3.5 5.0 4 0 0 4 4 4 2 I/LWEQ domain LcrG PF07216.7 GAM27905.1 - 0.0003 20.7 3.2 0.048 13.6 0.0 3.5 2 0 0 2 2 2 1 LcrG protein DUF2357 PF09823.4 GAM27905.1 - 0.0069 15.4 7.8 0.018 14.1 0.5 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2357) DELLA PF12041.3 GAM27905.1 - 0.029 14.0 0.3 0.27 10.9 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal DUF4484 PF14831.1 GAM27905.1 - 2.7 8.0 7.8 0.9 9.6 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4484) FtsA PF14450.1 GAM27905.1 - 5.8 6.7 11.4 3.7 7.3 0.1 3.9 4 1 0 4 4 4 0 Cell division protein FtsA OCD_Mu_crystall PF02423.10 GAM27906.1 - 1.1e-54 185.3 2.5 1.3e-54 185.1 1.7 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 GAM27906.1 - 2.3e-08 34.1 0.1 4.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 GAM27906.1 - 6.5e-05 22.0 0.2 0.00019 20.5 0.1 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dabb PF07876.7 GAM27907.1 - 2.6e-16 59.8 0.0 2.9e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain RMMBL PF07521.7 GAM27907.1 - 0.13 12.0 0.0 5 7.0 0.0 2.2 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase SET PF00856.23 GAM27909.1 - 1.1e-24 87.5 0.2 7.1e-24 84.9 0.0 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 GAM27909.1 - 3.2e-14 53.0 3.8 3.2e-14 53.0 2.6 2.1 2 0 0 2 2 2 1 Pre-SET motif DDE_Tnp_4 PF13359.1 GAM27910.1 - 3.2e-12 46.3 0.7 1.2e-10 41.1 0.4 2.5 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM27910.1 - 3.5e-05 23.4 1.6 4.6e-05 23.0 1.0 1.4 1 1 0 1 1 1 1 Transposase DDE domain SOG2 PF10428.4 GAM27911.1 - 0.036 12.7 2.3 0.035 12.7 1.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dicty_REP PF05086.7 GAM27911.1 - 4.2 5.0 6.4 6.3 4.4 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M48 PF01435.13 GAM27912.1 - 2.3e-27 96.0 0.2 7.3e-27 94.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 GAM27912.1 - 0.00044 19.3 0.2 0.0011 18.0 0.2 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 DCX PF03607.12 GAM27912.1 - 0.0031 17.0 0.2 0.019 14.5 0.0 2.3 3 0 0 3 3 3 1 Doublecortin FNIP PF05725.7 GAM27913.1 - 1e-53 178.9 11.1 9.2e-17 60.7 0.1 5.2 4 1 1 5 5 5 5 FNIP Repeat FNIP PF05725.7 GAM27914.1 - 1.4e-19 69.7 0.2 2.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 FNIP Repeat Pkinase PF00069.20 GAM27914.1 - 5.2e-17 61.8 0.2 2.5e-16 59.6 0.1 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27914.1 - 8.4e-09 34.8 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27914.1 - 0.0062 15.5 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like OB_NTP_bind PF07717.11 GAM27915.1 - 2.9e-23 81.8 0.0 9.2e-23 80.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM27915.1 - 4.1e-23 81.3 0.0 4.1e-23 81.3 0.0 3.3 3 0 0 3 3 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM27915.1 - 9.3e-14 51.0 0.0 2.5e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 GAM27915.1 - 4.8e-08 32.6 0.1 1.1e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 GAM27915.1 - 1.6e-05 25.0 0.1 3.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TLP-20 PF06088.6 GAM27915.1 - 0.0088 15.7 0.1 0.0088 15.7 0.1 4.5 4 1 0 4 4 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Flavi_DEAD PF07652.9 GAM27915.1 - 0.011 15.5 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SE PF00437.15 GAM27915.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 GAM27915.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 GAM27915.1 - 0.018 15.3 0.0 0.093 13.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 GAM27915.1 - 0.025 14.2 0.1 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 GAM27915.1 - 0.025 13.9 0.3 0.058 12.8 0.2 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 GAM27915.1 - 0.043 14.1 0.0 0.043 14.1 0.0 4.3 3 1 1 4 4 3 0 AAA domain AAA_14 PF13173.1 GAM27915.1 - 0.045 13.6 0.3 0.28 11.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAM27915.1 - 0.047 13.4 0.1 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 GAM27915.1 - 0.049 13.0 0.0 0.14 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 GAM27915.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain OB_NTP_bind PF07717.11 GAM27916.1 - 7.2e-35 119.2 0.1 2.4e-34 117.5 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 GAM27916.1 - 2.1e-27 95.1 0.1 2.1e-27 95.1 0.1 3.4 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 GAM27916.1 - 2.7e-11 43.1 0.0 7.2e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 GAM27916.1 - 3.1e-06 27.3 0.0 1.3e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 GAM27916.1 - 4.5e-06 26.2 0.0 1.6e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 GAM27916.1 - 0.00042 19.3 0.0 0.0013 17.7 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein PWI PF01480.12 GAM27916.1 - 0.00077 19.5 0.0 0.0025 17.8 0.0 1.9 1 0 0 1 1 1 1 PWI domain Flavi_DEAD PF07652.9 GAM27916.1 - 0.0035 17.1 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.1 GAM27916.1 - 0.2 11.9 0.1 0.2 11.9 0.1 4.6 2 1 2 4 4 4 0 AAA domain CLN5 PF15014.1 GAM27917.1 - 1.9e-17 63.5 9.9 3.2e-17 62.8 6.9 1.3 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 ATG27 PF09451.5 GAM27917.1 - 6.8e-07 28.7 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 GAM27917.1 - 0.0059 15.6 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ERM PF00769.14 GAM27918.1 - 0.0047 16.4 7.9 0.0047 16.4 5.5 2.0 1 1 1 2 2 2 1 Ezrin/radixin/moesin family ATP-synt_E_2 PF08112.6 GAM27918.1 - 0.19 11.7 6.2 4.6 7.3 0.3 3.2 3 0 0 3 3 3 0 ATP synthase epsilon subunit FUSC PF04632.7 GAM27918.1 - 0.71 8.2 4.2 0.89 7.9 2.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 GAM27918.1 - 1.9 8.8 20.0 0.14 12.4 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) ADIP PF11559.3 GAM27918.1 - 4.9 7.0 29.6 2.2 8.1 7.4 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 GAM27918.1 - 7.6 5.6 9.4 3.3 6.7 1.8 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein BBS2_Mid PF14783.1 GAM27919.1 - 1.1e-11 44.5 0.6 0.001 18.7 0.0 3.9 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 GAM27919.1 - 4.8e-11 42.0 0.0 0.00055 19.5 0.0 2.9 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 GAM27919.1 - 4e-07 30.2 1.7 0.028 14.7 0.3 3.4 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PHTB1_N PF14727.1 GAM27919.1 - 0.00026 20.0 0.8 0.05 12.5 0.0 3.0 1 1 0 2 2 2 1 PTHB1 N-terminus BBS2_C PF14782.1 GAM27919.1 - 0.0013 17.3 0.6 1.6 7.1 0.0 3.2 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal BBS1 PF14779.1 GAM27919.1 - 0.0024 16.9 0.0 0.99 8.3 0.0 2.3 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 Hira PF07569.6 GAM27919.1 - 0.053 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split PQQ_3 PF13570.1 GAM27919.1 - 0.14 12.4 0.6 2.2 8.6 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain DUF3852 PF12963.2 GAM27920.1 - 0.096 12.7 7.6 0.26 11.3 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) FKBP_C PF00254.23 GAM27921.1 - 1.4e-31 108.3 0.0 1.6e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4394 PF14339.1 GAM27922.1 - 1.6e-05 24.3 0.5 0.014 14.7 0.0 3.1 2 1 0 3 3 3 2 Domain of unknown function (DUF4394) Ank_2 PF12796.2 GAM27923.1 - 3.7e-57 190.6 2.3 2.1e-17 63.2 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) GDPD PF03009.12 GAM27923.1 - 1.5e-54 185.2 0.0 3e-54 184.2 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.1 GAM27923.1 - 5.2e-39 131.9 5.1 4.6e-09 36.5 0.0 6.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM27923.1 - 1.2e-38 128.9 6.2 1.2e-07 31.2 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 GAM27923.1 - 7.2e-29 96.9 7.2 1.9e-05 24.4 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 GAM27923.1 - 2.6e-27 94.2 5.4 1.9e-11 43.7 0.0 6.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) CBM_20 PF00686.14 GAM27923.1 - 2.6e-15 55.7 0.0 6.9e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain SPX PF03105.14 GAM27923.1 - 1.1e-10 41.7 0.1 1.1e-10 41.7 0.0 3.8 3 1 1 4 4 4 1 SPX domain tRNA-synt_2b PF00587.20 GAM27924.1 - 1.8e-62 210.0 0.0 8.5e-62 207.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM27924.1 - 9.2e-23 80.0 0.3 2.9e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain EF-hand_1 PF00036.27 GAM27925.1 - 2.4e-17 60.8 4.7 4.1e-06 25.6 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 GAM27925.1 - 1.6e-16 58.6 2.8 1.2e-05 24.7 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 GAM27925.1 - 3e-13 49.6 1.2 8e-09 35.5 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 GAM27925.1 - 4.3e-09 35.8 9.2 0.034 13.7 0.3 3.6 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 GAM27925.1 - 5.5e-09 34.9 3.8 0.00088 18.5 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 GAM27925.1 - 0.0023 17.8 0.1 2.2 8.2 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.1 GAM27925.1 - 0.0025 17.4 0.4 0.35 10.5 0.0 2.4 2 0 0 2 2 2 1 EF hand Caleosin PF05042.8 GAM27925.1 - 0.022 14.3 0.0 0.19 11.2 0.0 2.2 1 1 1 2 2 2 0 Caleosin related protein Dockerin_1 PF00404.13 GAM27925.1 - 0.033 13.9 1.0 0.033 13.9 0.7 3.1 3 0 0 3 3 3 0 Dockerin type I repeat SPARC_Ca_bdg PF10591.4 GAM27925.1 - 0.05 13.6 1.0 0.38 10.8 0.0 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TSP_3 PF02412.13 GAM27925.1 - 0.23 10.9 5.6 1.7 8.1 1.6 2.4 2 0 0 2 2 2 0 Thrombospondin type 3 repeat Fucokinase PF07959.7 GAM27927.1 - 1.4e-71 241.2 0.0 3e-71 240.1 0.0 1.5 1 1 0 1 1 1 1 L-fucokinase AATase PF07247.7 GAM27928.1 - 8e-07 27.9 0.3 3.5e-06 25.8 0.2 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 GAM27928.1 - 0.00088 18.2 0.1 0.0016 17.3 0.1 1.5 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 GAM27929.1 - 6.8e-10 38.0 2.9 5.6e-07 28.4 0.5 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 GAM27929.1 - 6.1e-06 25.2 0.5 1.7e-05 23.8 0.4 1.7 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 GAM27930.1 - 1.7e-17 63.2 0.2 6.8e-10 38.0 0.1 2.3 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 GAM27930.1 - 6e-07 28.5 0.4 3.7e-05 22.7 0.2 3.2 3 0 0 3 3 3 1 Condensation domain Apolipoprotein PF01442.13 GAM27931.1 - 1.5e-11 44.2 22.7 1.8e-08 34.1 9.6 2.7 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 GAM27931.1 - 0.00015 22.1 23.5 0.7 10.3 0.6 4.0 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 GAM27931.1 - 0.041 13.8 35.7 0.78 9.7 8.4 3.3 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.7 GAM27931.1 - 0.06 13.1 0.2 11 5.7 0.0 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.2 GAM27931.1 - 0.096 13.0 40.3 2.7 8.4 1.9 4.5 1 1 1 2 2 2 0 YtxH-like protein AT_hook PF02178.14 GAM27931.1 - 0.12 12.1 5.9 0.37 10.6 4.1 1.9 1 0 0 1 1 1 0 AT hook motif HAUS5 PF14817.1 GAM27931.1 - 0.87 8.0 14.7 0.046 12.2 5.6 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Peptidase_S64 PF08192.6 GAM27931.1 - 8.3 4.6 14.2 10 4.3 9.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2461 PF09365.5 GAM27931.1 - 9.1 5.6 11.8 1.6 8.0 4.1 2.3 1 1 1 2 2 2 0 Conserved hypothetical protein (DUF2461) Ribosomal_L18e PF00828.14 GAM27933.1 - 1.7e-18 67.2 0.2 2.9e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Hexapep PF00132.19 GAM27934.1 - 1.6e-11 43.1 20.9 1.9e-05 23.9 0.5 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM27934.1 - 0.0017 17.8 1.4 0.0017 17.8 0.9 4.0 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase UPF0047 PF01894.12 GAM27936.1 - 2.2e-24 85.5 0.0 2.4e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 E3_UbLigase_R4 PF13764.1 GAM27937.1 - 4.6e-189 630.0 8.4 4.6e-189 630.0 5.8 3.0 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.12 GAM27937.1 - 3e-11 42.6 6.3 3e-11 42.6 4.4 3.2 3 0 0 3 3 3 1 Zinc finger, ZZ type UIM PF02809.15 GAM27937.1 - 0.0078 15.6 7.7 0.016 14.7 1.6 3.0 2 0 0 2 2 2 1 Ubiquitin interaction motif Mog1 PF04603.7 GAM27938.1 - 3.5e-38 130.7 0.3 4.6e-38 130.3 0.2 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Rap_GAP PF02145.10 GAM27940.1 - 3.1e-54 183.2 1.0 4.9e-54 182.5 0.7 1.3 1 0 0 1 1 1 1 Rap/ran-GAP NAGLU PF05089.7 GAM27941.1 - 1.9e-137 457.5 9.6 2.5e-137 457.1 6.7 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 GAM27941.1 - 1.4e-64 218.0 4.0 1.9e-64 217.6 2.8 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 GAM27941.1 - 4.6e-19 67.8 0.0 9.3e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Pax2_C PF12403.3 GAM27941.1 - 0.0016 18.0 0.2 0.0037 16.8 0.1 1.6 1 0 0 1 1 1 1 Paired-box protein 2 C terminal GST_N PF02798.15 GAM27942.1 - 4.4e-15 55.6 0.0 7.8e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM27942.1 - 1.2e-08 34.7 0.1 2.1e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 GAM27942.1 - 4.3e-07 30.3 0.0 8.7e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 GAM27942.1 - 0.0018 18.0 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM27942.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LRR_6 PF13516.1 GAM27944.1 - 8.6e-13 46.9 50.7 0.38 10.9 0.1 12.8 11 1 1 12 12 12 6 Leucine Rich repeat LRR_1 PF00560.28 GAM27944.1 - 1.8e-08 33.2 32.2 6.9 7.1 0.0 12.6 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_4 PF12799.2 GAM27944.1 - 5.7e-07 29.0 47.0 0.012 15.2 0.4 8.8 5 5 5 10 10 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM27944.1 - 0.16 11.7 45.8 4.2 7.1 0.9 8.6 4 4 2 6 6 6 0 Leucine rich repeat PDEase_II PF02112.10 GAM27945.1 - 2.3e-82 276.6 0.1 2.8e-82 276.3 0.1 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAM27945.1 - 0.0017 17.9 0.2 0.0055 16.2 0.1 1.9 1 1 1 2 2 2 1 Beta-lactamase superfamily domain UCH PF00443.24 GAM27946.1 - 1.9e-18 66.5 0.3 1.6e-17 63.5 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM27946.1 - 0.00023 20.7 0.3 0.00069 19.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CBM_20 PF00686.14 GAM27946.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Starch binding domain RRF PF01765.14 GAM27947.1 - 9.3e-46 155.3 0.3 1.1e-45 155.0 0.2 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF1007 PF06226.8 GAM27947.1 - 0.047 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) TFIIF_alpha PF05793.7 GAM27948.1 - 0.42 8.9 40.4 0.75 8.0 28.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4199 PF13858.1 GAM27949.1 - 0.046 13.6 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Tim17 PF02466.14 GAM27949.1 - 1.8 8.6 6.6 20 5.2 4.7 2.2 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Pex14_N PF04695.8 GAM27949.1 - 4.2 7.4 8.1 0.26 11.3 1.2 2.2 2 2 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ELFV_dehydrog PF00208.16 GAM27950.1 - 1.8e-49 168.5 0.0 2.5e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 GAM27950.1 - 3.9e-25 87.5 0.1 4.5e-17 60.8 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 GAM27950.1 - 0.0078 15.7 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Endotoxin_N PF03945.9 GAM27951.1 - 1.4e-23 83.5 2.5 1.4e-23 83.5 1.7 1.6 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Epimerase PF01370.16 GAM27952.1 - 3.6e-12 46.2 0.1 8.9e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM27952.1 - 9.1e-12 45.3 0.0 1.5e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM27952.1 - 1.5e-07 30.9 1.9 2.3e-07 30.3 1.3 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.10 GAM27952.1 - 0.0003 20.6 0.3 0.00054 19.8 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 GAM27952.1 - 0.001 19.0 0.7 0.0033 17.3 0.0 2.0 2 1 1 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 GAM27952.1 - 0.0015 17.5 0.4 0.0057 15.5 0.3 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 GAM27952.1 - 0.016 15.2 0.2 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4431 PF14485.1 GAM27952.1 - 0.06 12.9 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) DXP_reductoisom PF02670.11 GAM27952.1 - 0.08 13.4 1.0 0.29 11.6 0.2 2.4 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3HCDH_N PF02737.13 GAM27952.1 - 0.097 12.3 4.3 0.58 9.7 0.0 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-A20 PF01754.11 GAM27953.1 - 1e-08 34.6 7.6 1e-08 34.6 5.3 2.5 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.11 GAM27953.1 - 2.9e-07 30.2 5.9 2.9e-07 30.2 4.1 1.7 2 0 0 2 2 2 1 AN1-like Zinc finger CitT PF12431.3 GAM27955.1 - 7.7 6.7 7.1 12 6.1 0.1 3.8 3 0 0 3 3 3 0 Transcriptional regulator BAR PF03114.13 GAM27956.1 - 1e-18 67.6 14.5 1.2e-18 67.5 10.1 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 GAM27956.1 - 6.7e-08 32.1 14.7 8.8e-08 31.7 10.2 1.1 1 0 0 1 1 1 1 Arfaptin-like domain BAR_2 PF10455.4 GAM27956.1 - 1e-07 31.2 12.9 1.3e-07 30.8 8.9 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking NolX PF05819.6 GAM27956.1 - 0.00092 17.7 0.7 0.0011 17.3 0.5 1.2 1 0 0 1 1 1 1 NolX protein FCD PF07729.7 GAM27956.1 - 0.0088 16.3 0.3 0.022 15.0 0.2 1.6 1 0 0 1 1 1 1 FCD domain FadA PF09403.5 GAM27956.1 - 0.13 12.2 9.8 0.025 14.5 3.0 2.2 2 0 0 2 2 2 0 Adhesion protein FadA V-ATPase_H_C PF11698.3 GAM27956.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.5 2 1 1 3 3 3 0 V-ATPase subunit H PTPA PF03095.10 GAM27956.1 - 1 8.4 4.3 0.32 10.1 1.1 1.5 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Vps5 PF09325.5 GAM27956.1 - 1.4 8.1 15.4 0.063 12.5 4.1 2.7 2 1 1 3 3 3 0 Vps5 C terminal like HALZ PF02183.13 GAM27956.1 - 2.1 8.1 6.7 1 9.1 0.4 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIVA PF05103.8 GAM27956.1 - 7 6.7 11.0 1.5 8.8 3.1 2.3 2 1 0 2 2 2 0 DivIVA protein Reo_sigmaC PF04582.7 GAM27957.1 - 0.0052 16.0 1.2 0.01 15.0 0.1 1.8 2 0 0 2 2 2 1 Reovirus sigma C capsid protein HALZ PF02183.13 GAM27957.1 - 0.0055 16.3 3.3 0.24 11.1 0.3 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF1664 PF07889.7 GAM27957.1 - 0.042 13.6 4.0 0.074 12.8 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ly49 PF08391.5 GAM27957.1 - 0.084 12.9 6.4 0.19 11.8 4.4 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region IncA PF04156.9 GAM27957.1 - 0.085 12.4 7.6 0.14 11.6 5.3 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 GAM27957.1 - 0.087 12.0 8.2 0.14 11.3 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2514 PF10721.4 GAM27957.1 - 0.088 12.5 2.6 0.15 11.7 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF342 PF03961.8 GAM27957.1 - 0.38 9.1 5.4 0.62 8.4 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 GAM27957.1 - 0.45 10.0 14.4 0.077 12.5 7.2 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Ndc1_Nup PF09531.5 GAM27957.1 - 0.99 7.7 11.2 1.1 7.6 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bud13 PF09736.4 GAM27957.1 - 1.7 8.9 11.9 4.5 7.5 4.5 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex COG5 PF10392.4 GAM27957.1 - 3.7 7.5 9.1 0.75 9.7 2.4 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HlyD_2 PF12700.2 GAM27957.1 - 3.7 6.6 8.5 0.4 9.7 2.8 1.6 2 0 0 2 2 2 0 HlyD family secretion protein bZIP_2 PF07716.10 GAM27957.1 - 8 6.3 11.4 2.5 7.9 0.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper XkdW PF09636.5 GAM27957.1 - 8.5 6.2 7.4 6.6 6.6 3.2 2.1 1 1 1 2 2 2 0 XkdW protein Arf PF00025.16 GAM27958.1 - 1.2e-74 249.3 0.0 1.4e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 GAM27958.1 - 2.6e-12 46.1 0.7 3.3e-08 32.6 0.1 2.7 2 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 GAM27958.1 - 3.3e-11 42.8 0.0 3.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM27958.1 - 7.6e-11 41.5 0.0 9.3e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM27958.1 - 9.1e-09 34.7 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM27958.1 - 1.4e-08 35.2 0.0 1.9e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM27958.1 - 1.8e-05 24.6 0.0 4.7e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM27958.1 - 0.00053 19.4 0.1 0.0055 16.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 GAM27958.1 - 0.047 12.4 0.1 0.33 9.6 0.0 2.3 2 1 0 2 2 2 0 ArgK protein WH2 PF02205.15 GAM27959.1 - 0.00018 21.0 0.2 0.024 14.2 0.0 2.5 1 1 1 2 2 2 2 WH2 motif Apc4_WD40 PF12894.2 GAM27960.1 - 2.2e-11 43.0 0.1 5.7e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Apc4 PF12896.2 GAM27960.1 - 1.9e-10 40.3 1.1 3.1e-10 39.7 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 GAM27960.1 - 0.045 13.6 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat LRR_6 PF13516.1 GAM27961.1 - 1.7e-45 147.9 69.7 0.0012 18.6 0.2 18.3 19 0 0 19 19 19 15 Leucine Rich repeat LRR_4 PF12799.2 GAM27961.1 - 1.1e-28 98.3 46.5 2.4e-05 23.8 1.0 10.8 7 2 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM27961.1 - 1.8e-19 66.7 36.2 1.4 9.2 0.0 17.0 16 3 0 16 16 16 5 Leucine Rich Repeat LRR_8 PF13855.1 GAM27961.1 - 2.3e-08 33.6 63.4 0.011 15.5 3.0 10.6 3 3 9 12 12 12 8 Leucine rich repeat LRR_7 PF13504.1 GAM27961.1 - 1.1e-06 27.8 40.9 8.3 7.1 0.0 15.1 16 0 0 16 16 16 3 Leucine rich repeat ECH_C PF13766.1 GAM27961.1 - 0.099 12.7 0.6 1.8 8.7 0.0 3.2 4 0 0 4 4 4 0 2-enoyl-CoA Hydratase C-terminal region RabGAP-TBC PF00566.13 GAM27962.1 - 8.4e-30 103.8 1.9 2.6e-29 102.2 1.3 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TLD PF07534.11 GAM27962.1 - 5.2e-23 81.5 0.0 1.1e-22 80.5 0.0 1.6 1 0 0 1 1 1 1 TLD FAP PF07174.6 GAM27965.1 - 0.065 12.5 27.6 0.088 12.0 19.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RhoGAP PF00620.22 GAM27966.1 - 2.8e-27 95.2 0.1 2.2e-26 92.2 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 GAM27966.1 - 2.5e-14 53.2 0.2 2.5e-14 53.2 0.1 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SPX PF03105.14 GAM27966.1 - 0.0039 17.0 2.4 0.0039 17.0 1.7 2.8 3 0 0 3 3 3 1 SPX domain ATP-synt_B PF00430.13 GAM27966.1 - 1.1 9.0 7.5 0.34 10.7 2.3 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF904 PF06005.7 GAM27967.1 - 0.00087 19.5 1.4 0.0027 17.9 1.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF4618 PF15397.1 GAM27967.1 - 0.0065 15.8 3.4 0.0065 15.8 2.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) Filament PF00038.16 GAM27967.1 - 0.0084 15.6 2.7 0.22 10.9 1.8 2.3 2 0 0 2 2 2 1 Intermediate filament protein MAD PF05557.8 GAM27967.1 - 0.0097 14.0 2.8 0.013 13.6 2.0 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF2205 PF10224.4 GAM27967.1 - 0.019 14.5 1.1 0.066 12.7 0.8 1.9 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) DivIC PF04977.10 GAM27967.1 - 0.056 12.9 2.2 0.15 11.5 0.9 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 GAM27967.1 - 0.087 13.1 2.6 0.24 11.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RHH_4 PF13467.1 GAM27967.1 - 0.099 12.5 0.2 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix domain NPV_P10 PF05531.7 GAM27967.1 - 0.23 11.7 3.3 0.59 10.4 2.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 GAM27967.1 - 0.27 11.6 4.6 1.4 9.3 1.7 2.6 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Rootletin PF15035.1 GAM27967.1 - 1.8 8.5 7.8 1.9 8.4 3.9 2.2 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF489 PF04356.7 GAM27968.1 - 0.45 10.0 5.4 0.96 9.0 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF489) DUF572 PF04502.8 GAM27968.1 - 0.55 9.3 21.0 0.87 8.7 14.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribophorin_I PF04597.9 GAM27971.1 - 1.2e-118 396.4 1.4 2.1e-118 395.6 1.0 1.4 1 0 0 1 1 1 1 Ribophorin I IncA PF04156.9 GAM27971.1 - 0.31 10.6 7.2 0.067 12.7 2.5 1.6 2 0 0 2 2 2 0 IncA protein TIP49 PF06068.8 GAM27972.1 - 1.1e-188 626.9 0.9 1.4e-188 626.6 0.6 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 GAM27972.1 - 3.4e-11 43.4 1.2 2.3e-07 31.0 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 GAM27972.1 - 6.4e-10 38.4 1.4 5.7e-06 25.5 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 GAM27972.1 - 1e-06 28.9 0.1 0.054 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM27972.1 - 3.7e-06 27.0 0.0 0.00038 20.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 GAM27972.1 - 2e-05 24.3 0.1 0.0032 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 GAM27972.1 - 8.5e-05 22.2 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 GAM27972.1 - 8.6e-05 22.0 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 GAM27972.1 - 0.00021 21.1 0.0 0.53 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 GAM27972.1 - 0.00037 19.9 0.1 0.00089 18.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 GAM27972.1 - 0.0048 16.0 4.1 0.039 13.0 0.1 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 GAM27972.1 - 0.005 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 GAM27972.1 - 0.0071 15.4 0.2 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 GAM27972.1 - 0.0092 15.4 0.1 2.3 7.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DnaB_C PF03796.10 GAM27972.1 - 0.017 14.0 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mucin PF01456.12 GAM27972.1 - 0.024 14.3 23.7 0.046 13.4 16.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein AAA_18 PF13238.1 GAM27972.1 - 0.042 14.1 0.1 0.11 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 GAM27972.1 - 0.044 13.0 0.1 0.044 13.0 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 GAM27972.1 - 0.056 13.3 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 GAM27972.1 - 0.059 13.0 0.1 0.16 11.6 0.0 1.7 2 0 0 2 2 1 0 NACHT domain DUF2075 PF09848.4 GAM27972.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 GAM27972.1 - 0.071 13.9 0.0 0.18 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 GAM27972.1 - 0.092 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 GAM27972.1 - 0.15 11.9 3.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NAP PF00956.13 GAM27974.1 - 9.4e-45 152.6 3.7 9.4e-45 152.6 2.5 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) OmpH PF03938.9 GAM27974.1 - 0.0027 17.6 0.1 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4611 PF15387.1 GAM27974.1 - 4.3 7.5 21.2 0.031 14.4 3.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 GAM27974.1 - 4.4 6.8 18.2 3.6 7.0 7.3 2.8 3 0 0 3 3 3 0 Nucleoplasmin Pkinase PF00069.20 GAM27975.1 - 9.9e-67 224.8 0.0 3.3e-42 144.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27975.1 - 1.1e-30 106.5 0.0 2e-23 82.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.19 GAM27975.1 - 1.1e-18 67.1 0.1 2.1e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 PX domain PH PF00169.24 GAM27975.1 - 6.1e-15 55.2 0.0 1.5e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 GAM27975.1 - 1.2e-06 27.6 0.0 0.00018 20.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like PH_11 PF15413.1 GAM27975.1 - 0.00025 21.2 1.5 0.002 18.3 0.3 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain APH PF01636.18 GAM27975.1 - 0.0014 18.4 1.3 0.0029 17.3 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH_8 PF15409.1 GAM27975.1 - 0.032 14.3 0.0 0.089 12.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Vel1p PF10339.4 GAM27976.1 - 0.03 13.4 0.1 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive Vps35 PF03635.12 GAM27977.1 - 2.8e-262 872.3 26.4 3.3e-262 872.0 18.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Cyclin_N PF00134.18 GAM27978.1 - 6.1e-14 51.6 1.4 2.2e-13 49.8 0.2 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 GAM27978.1 - 0.00014 21.5 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin PF08613.6 GAM27978.1 - 0.00073 19.9 0.2 0.00073 19.9 0.1 1.8 2 0 0 2 2 2 1 Cyclin Tmemb_170 PF10190.4 GAM27979.1 - 3.1e-14 52.8 8.0 4e-14 52.5 5.5 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Alpha-amylase PF00128.19 GAM27980.1 - 2.3e-20 73.2 0.8 2.1e-19 70.0 0.6 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 GAM27980.1 - 0.011 14.6 0.2 0.021 13.7 0.2 1.5 1 1 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Prokineticin PF06607.6 GAM27981.1 - 0.00057 19.9 2.9 0.00057 19.9 2.0 3.1 2 2 1 3 3 3 1 Prokineticin Dopey_N PF04118.9 GAM27983.1 - 5.8e-90 301.1 0.5 5.8e-90 301.1 0.3 2.5 2 0 0 2 2 2 1 Dopey, N-terminal ATP-synt_ab PF00006.20 GAM27984.1 - 3.4e-62 209.7 0.0 5.2e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM27984.1 - 4.6e-24 85.0 0.4 1.5e-23 83.3 0.3 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM27984.1 - 1.5e-19 69.9 1.1 1.9e-18 66.4 0.7 2.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.1 GAM27984.1 - 0.011 15.9 0.0 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 GAM27984.1 - 0.011 15.4 0.5 0.91 9.2 0.1 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 GAM27984.1 - 0.021 15.0 0.3 0.26 11.4 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 GAM27984.1 - 0.021 14.7 0.2 0.1 12.5 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 GAM27984.1 - 0.022 13.9 0.1 0.043 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 VitK2_biosynth PF02621.9 GAM27984.1 - 0.027 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Menaquinone biosynthesis NACHT PF05729.7 GAM27984.1 - 0.03 13.9 0.1 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 GAM27984.1 - 0.032 14.4 0.3 0.37 10.9 0.0 2.9 4 0 0 4 4 3 0 RNA helicase KaiC PF06745.8 GAM27984.1 - 0.043 12.9 1.8 0.059 12.4 0.2 2.1 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 GAM27984.1 - 0.045 13.1 0.7 0.19 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 GAM27984.1 - 0.047 13.3 1.7 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 GAM27984.1 - 0.065 12.0 1.7 0.11 11.3 0.2 1.9 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 GAM27984.1 - 0.099 12.9 2.9 0.68 10.2 0.2 2.9 3 0 0 3 3 3 0 ABC transporter 3-HAO PF06052.7 GAM27985.1 - 1.1e-60 203.4 0.1 1.3e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 GAM27985.1 - 6.6e-06 25.5 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 GAM27985.1 - 0.0049 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Cupin zf-CHY PF05495.7 GAM27985.1 - 0.041 14.0 0.7 5.6 7.2 0.0 2.3 2 0 0 2 2 2 0 CHY zinc finger AraC_binding PF02311.14 GAM27985.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.2 GAM27985.1 - 0.065 12.8 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF2296 PF10058.4 GAM27985.1 - 0.11 12.2 0.7 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Cytochrome_C7 PF14522.1 GAM27985.1 - 0.2 11.2 4.1 5.1 6.8 3.3 2.1 1 1 1 2 2 2 0 Cytochrome c7 NAM PF02365.10 GAM27986.1 - 2.8e-05 24.3 2.4 7e-05 23.0 0.8 2.2 2 0 0 2 2 2 1 No apical meristem (NAM) protein FNIP PF05725.7 GAM27987.1 - 1.1e-54 182.1 23.2 4e-10 39.4 1.7 8.5 6 1 4 10 10 10 9 FNIP Repeat LRR_5 PF13306.1 GAM27987.1 - 0.061 13.0 0.0 6.1 6.5 0.0 2.7 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) DUF1769 PF08588.5 GAM27987.1 - 0.08 12.9 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) LRR_7 PF13504.1 GAM27987.1 - 0.16 12.2 5.8 34 5.2 0.0 6.3 8 1 0 8 8 8 0 Leucine rich repeat Glyco_hydro_35 PF01301.14 GAM27988.1 - 6.7e-106 354.2 7.8 8.8e-106 353.8 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Palm_thioest PF02089.10 GAM27989.1 - 2.5e-109 364.5 0.1 2.9e-109 364.3 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.13 GAM27989.1 - 0.00031 20.1 0.0 0.00076 18.8 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.15 GAM27989.1 - 0.00089 18.8 0.0 0.0055 16.2 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold RuBisCO_small PF00101.15 GAM27989.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain DUF915 PF06028.6 GAM27989.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FNIP PF05725.7 GAM27990.1 - 9.4e-58 191.9 10.1 1.8e-10 40.5 0.1 7.8 5 1 3 8 8 8 8 FNIP Repeat RE_SinI PF09570.5 GAM27990.1 - 0.22 10.4 0.4 6.7 5.6 0.0 3.0 2 1 2 4 4 4 0 SinI restriction endonuclease Glyco_hydro_35 PF01301.14 GAM27991.1 - 4.9e-92 308.6 11.8 6.6e-92 308.2 8.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 DUF2794 PF10984.3 GAM27991.1 - 0.2 11.5 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) Pkinase PF00069.20 GAM27992.1 - 4.7e-64 216.0 0.0 3.1e-63 213.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM27992.1 - 2e-48 164.7 0.0 3.5e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM27992.1 - 9.7e-09 34.5 0.2 1.7e-06 27.2 0.0 2.6 3 0 0 3 3 3 2 Kinase-like RIO1 PF01163.17 GAM27992.1 - 0.006 15.9 0.1 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 RIO1 family gp37_C PF12604.3 GAM27992.1 - 0.0063 16.2 1.7 0.011 15.4 1.2 1.4 1 0 0 1 1 1 1 Tail fiber protein gp37 C terminal PIRT PF15099.1 GAM27992.1 - 0.6 9.3 3.7 0.22 10.7 0.1 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family EF-hand_1 PF00036.27 GAM27995.1 - 1.6e-23 80.1 12.8 3.9e-05 22.6 1.0 4.7 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 GAM27995.1 - 1.3e-22 79.6 13.9 2.4e-10 40.3 0.4 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 GAM27995.1 - 9.4e-19 65.5 10.6 7.5e-05 22.2 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 GAM27995.1 - 4.9e-16 57.2 19.4 0.0003 19.9 0.1 5.1 5 1 1 6 6 6 4 EF hand EF-hand_8 PF13833.1 GAM27995.1 - 4.3e-10 39.0 16.6 0.0014 18.2 1.1 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM27995.1 - 2.5e-07 30.7 0.2 0.011 15.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 GAM27995.1 - 1.9e-06 27.5 8.1 0.043 13.5 0.4 3.6 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 GAM27995.1 - 0.081 12.8 0.5 2.6 8.0 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain EF-hand_2 PF09068.6 GAM27995.1 - 0.11 12.5 0.2 9.8 6.2 0.0 2.6 2 1 1 3 3 3 0 EF hand Homeobox PF00046.24 GAM27996.1 - 3.8e-15 55.2 7.7 6.6e-15 54.4 5.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAM27996.1 - 5.9e-06 25.8 0.1 1.6e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 GAM27996.1 - 0.026 13.5 0.3 0.05 12.6 0.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Beta-lactamase PF00144.19 GAM27997.1 - 1e-34 120.0 0.0 1.9e-34 119.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Ded_cyto PF06920.8 GAM27998.1 - 7.8e-40 136.0 1.2 1.7e-39 134.9 0.4 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM27998.1 - 9e-23 80.8 0.0 2.3e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.1 GAM27998.1 - 1.6e-06 27.5 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM27998.1 - 8.7e-05 21.8 0.0 0.00021 20.6 0.0 1.7 1 0 0 1 1 1 1 SH3 domain FNIP PF05725.7 GAM27999.1 - 4.1e-59 196.2 11.9 1.1e-12 47.6 0.1 7.0 3 1 6 9 9 9 8 FNIP Repeat LRR_6 PF13516.1 GAM27999.1 - 0.055 13.5 6.9 54 4.3 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 GAM27999.1 - 5.2 7.7 10.5 94 3.9 0.0 6.3 8 0 0 8 8 8 0 Leucine rich repeat FNIP PF05725.7 GAM28000.1 - 3.6e-61 202.8 33.1 9e-15 54.3 0.7 7.2 3 2 4 7 7 7 7 FNIP Repeat FNIP PF05725.7 GAM28001.1 - 7.8e-62 204.9 42.2 5.7e-16 58.2 0.2 7.2 4 1 3 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 GAM28001.1 - 0.12 12.0 2.9 7.2 6.3 0.0 3.6 4 1 0 4 4 4 0 Leucine rich repeats (6 copies) FNIP PF05725.7 GAM28002.1 - 7.6e-65 214.6 14.6 1.1e-13 50.9 0.1 8.2 5 1 3 9 9 9 8 FNIP Repeat LRR_5 PF13306.1 GAM28002.1 - 0.11 12.2 0.0 28 4.4 0.0 3.0 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) DUF1191 PF06697.7 GAM28003.1 - 0.0048 15.7 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) EGF_2 PF07974.8 GAM28003.1 - 5.3 7.3 15.1 15 5.8 10.5 1.8 1 0 0 1 1 1 0 EGF-like domain Ras PF00071.17 GAM28004.1 - 1.9e-47 160.6 0.0 2.3e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28004.1 - 1e-16 61.4 0.0 1.5e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28004.1 - 1.9e-11 43.5 0.0 2.3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM28004.1 - 6.1e-07 29.0 0.1 0.00014 21.3 0.0 2.6 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM28004.1 - 1.4e-06 27.6 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 GAM28004.1 - 7.4e-05 22.6 0.0 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 GAM28004.1 - 0.00087 19.0 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 GAM28004.1 - 0.0012 18.3 0.0 0.013 14.9 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 GAM28004.1 - 0.0025 17.3 0.3 0.07 12.5 0.1 2.3 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 GAM28004.1 - 0.0059 16.7 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 GAM28004.1 - 0.015 14.4 0.1 0.025 13.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 GAM28004.1 - 0.018 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 GAM28004.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.1 GAM28004.1 - 0.046 13.6 0.1 0.068 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 GAM28004.1 - 0.062 12.5 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 GAM28004.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Dynamin family ATP_bind_1 PF03029.12 GAM28004.1 - 0.14 11.7 0.1 12 5.3 0.0 2.6 1 1 2 3 3 3 0 Conserved hypothetical ATP binding protein FNIP PF05725.7 GAM28006.1 - 3.8e-69 228.3 24.8 1.5e-12 47.2 0.6 8.0 4 1 4 9 9 9 8 FNIP Repeat Coiled PF05710.7 GAM28007.1 - 1.5e-11 44.5 11.2 1.8e-11 44.3 7.8 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.7 GAM28008.1 - 5.5e-13 49.1 15.1 6.5e-13 48.9 10.5 1.1 1 0 0 1 1 1 1 Coiled coil Pet191_N PF10203.4 GAM28009.1 - 0.025 14.6 1.6 0.025 14.6 1.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF2207 PF09972.4 GAM28010.1 - 0.00028 19.6 0.2 0.00032 19.4 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Amidase02_C PF12123.3 GAM28010.1 - 0.02 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Arif-1 PF06770.6 GAM28010.1 - 0.048 13.0 1.1 0.067 12.5 0.8 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF3753 PF12575.3 GAM28010.1 - 2.1 8.2 7.9 1.2 9.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) DUF4131 PF13567.1 GAM28010.1 - 2.8 7.3 5.2 4.5 6.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PBP1_TM PF14812.1 GAM28011.1 - 2 8.7 4.9 12 6.2 1.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UCH PF00443.24 GAM28012.1 - 4.7e-64 216.0 18.1 4.1e-63 212.9 12.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM28012.1 - 3.3e-29 102.2 23.5 5.1e-28 98.3 16.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sod_Cu PF00080.15 GAM28013.1 - 1e-30 106.7 0.2 1.8e-27 96.1 0.0 2.1 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) HD-ZIP_N PF04618.7 GAM28013.1 - 0.1 13.1 0.1 0.17 12.4 0.1 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF2012 PF09430.5 GAM28014.1 - 3.4e-18 65.6 0.1 0.049 13.4 0.0 9.3 11 0 0 11 11 11 5 Protein of unknown function (DUF2012) Cna_B PF05738.8 GAM28014.1 - 3.8e-07 29.7 54.1 0.015 15.0 0.7 13.4 11 3 2 13 13 13 6 Cna protein B-type domain DUF4365 PF14280.1 GAM28014.1 - 2e-06 27.5 0.6 4.6 6.9 0.0 6.3 7 0 0 7 7 7 2 Domain of unknown function (DUF4365) Y_Y_Y PF07495.8 GAM28014.1 - 3.2e-05 23.5 24.7 3.5 7.4 0.0 9.6 11 0 0 11 11 11 4 Y_Y_Y domain Orthopox_F8 PF05886.6 GAM28014.1 - 0.0038 17.0 4.3 36 4.2 0.0 7.0 8 0 0 8 8 8 0 Orthopoxvirus F8 protein Imm36 PF15597.1 GAM28014.1 - 0.0039 17.3 0.0 55 3.9 0.0 6.0 7 0 0 7 7 7 0 Immunity protein 36 CarboxypepD_reg PF13620.1 GAM28014.1 - 0.019 14.9 0.1 0.019 14.9 0.0 14.3 12 3 1 14 14 14 0 Carboxypeptidase regulatory-like domain eIF_4EBP PF05456.6 GAM28018.1 - 3.8e-22 78.1 10.6 1.6e-20 72.8 7.3 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pox_A12 PF04651.8 GAM28018.1 - 3.8 7.5 5.6 6.3 6.8 1.2 2.0 2 0 0 2 2 2 0 Poxvirus A12 protein DnaJ PF00226.26 GAM28019.1 - 1.9e-20 72.3 0.5 1.9e-20 72.3 0.4 1.8 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.17 GAM28019.1 - 6.7e-06 25.6 1.2 0.00094 18.7 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28019.1 - 0.00016 21.5 0.1 0.00081 19.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MRI PF15325.1 GAM28019.1 - 0.071 14.0 0.7 0.071 14.0 0.5 2.6 2 1 0 2 2 2 0 Modulator of retrovirus infection Selenoprotein_S PF06936.6 GAM28019.1 - 1.8 8.0 17.0 4.6 6.7 11.8 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) V_ATPase_I PF01496.14 GAM28019.1 - 5.4 4.7 16.1 6.6 4.4 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mit_KHE1 PF10173.4 GAM28019.1 - 7.2 6.4 12.6 4 7.2 6.8 2.0 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related DAGK_cat PF00781.19 GAM28020.1 - 6.8e-24 83.7 0.0 2.1e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 GAM28020.1 - 0.0012 17.6 0.0 0.0022 16.7 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF3456 PF11938.3 GAM28020.1 - 0.03 14.3 0.1 0.03 14.3 0.1 2.1 3 0 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP Tox-MPTase3 PF15639.1 GAM28020.1 - 0.085 12.6 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 Metallopeptidase toxin 3 RPA_interact_M PF14767.1 GAM28020.1 - 0.18 12.6 2.1 0.62 10.8 1.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting middle Occludin_ELL PF07303.8 GAM28020.1 - 7.6 7.3 11.6 0.5 11.1 0.2 2.9 3 0 0 3 3 3 0 Occludin homology domain XPG_N PF00752.12 GAM28021.1 - 6.7e-24 84.0 0.0 2.5e-23 82.2 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAM28021.1 - 5.2e-22 77.7 0.0 3.8e-21 74.9 0.0 2.6 1 0 0 1 1 1 1 XPG I-region DUF4414 PF14377.1 GAM28021.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF4414) Mucin PF01456.12 GAM28021.1 - 4.8 6.9 35.1 0.23 11.2 12.7 3.7 3 0 0 3 3 3 0 Mucin-like glycoprotein RUN PF02759.14 GAM28022.1 - 0.0019 17.9 0.3 0.0069 16.1 0.0 2.1 2 1 0 2 2 2 1 RUN domain zf-U1 PF06220.7 GAM28023.1 - 1.2e-06 27.9 0.4 2.5e-06 26.9 0.3 1.6 1 0 0 1 1 1 1 U1 zinc finger FDC-SP PF15215.1 GAM28023.1 - 0.058 13.7 2.0 0.23 11.7 1.4 2.0 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide Cu-oxidase_4 PF02578.10 GAM28023.1 - 1.1 8.2 9.1 0.048 12.7 1.7 2.0 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase Coiled PF05710.7 GAM28025.1 - 6.9e-10 39.2 14.1 8.7e-10 38.9 9.8 1.1 1 0 0 1 1 1 1 Coiled coil Amidase PF01425.16 GAM28026.1 - 3.1e-134 448.1 0.4 3.5e-134 447.9 0.3 1.0 1 0 0 1 1 1 1 Amidase Radical_SAM PF04055.16 GAM28027.1 - 8.8e-36 123.5 0.0 1.8e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 GAM28027.1 - 8.9e-31 105.6 0.2 2e-30 104.4 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 GAM28027.1 - 1.9e-05 24.3 0.0 3.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.1 GAM28027.1 - 0.072 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain Zip PF02535.17 GAM28027.1 - 0.17 10.8 3.4 0.28 10.1 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Melibiase PF02065.13 GAM28028.1 - 7.4e-21 74.2 0.1 8.9e-17 60.8 0.0 2.3 1 1 1 2 2 2 2 Melibiase Glyco_hydro_97 PF10566.4 GAM28028.1 - 0.0001 21.4 0.5 0.00016 20.8 0.4 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Glycogen_syn PF05693.8 GAM28028.1 - 0.085 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase TrbC PF04956.8 GAM28028.1 - 0.42 10.6 4.4 0.26 11.3 0.9 2.2 3 0 0 3 3 3 0 TrbC/VIRB2 family Med15 PF09606.5 GAM28029.1 - 0.65 8.1 57.7 0.88 7.6 40.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BNR_3 PF13859.1 GAM28029.1 - 0.95 8.4 5.0 1.3 8.0 3.0 1.5 2 0 0 2 2 2 0 BNR repeat-like domain CBS PF00571.23 GAM28030.1 - 2.4e-25 88.0 6.9 2.1e-09 37.0 0.0 4.4 4 0 0 4 4 4 4 CBS domain ThiF PF00899.16 GAM28031.1 - 4.1e-59 198.2 1.1 1.4e-34 118.8 0.0 3.0 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 GAM28031.1 - 6.9e-43 145.7 0.3 1.8e-42 144.4 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 GAM28031.1 - 1.3e-39 133.5 9.7 1.2e-25 88.8 0.1 4.1 4 1 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 GAM28031.1 - 3.9e-25 86.9 0.1 1.8e-21 75.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site adh_short PF00106.20 GAM28031.1 - 0.19 11.6 0.4 3 7.7 0.1 2.6 2 1 1 3 3 3 0 short chain dehydrogenase CDC50 PF03381.10 GAM28032.1 - 1.6e-94 316.1 0.8 2.1e-94 315.7 0.1 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Oxysterol_BP PF01237.13 GAM28033.1 - 2.6e-47 161.0 0.2 4e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Herpes_TAF50 PF03326.8 GAM28033.1 - 0.012 14.6 0.3 0.015 14.2 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF1084 PF06454.6 GAM28034.1 - 9.3e-15 54.4 21.0 1.1e-14 54.1 14.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF373 PF04123.8 GAM28034.1 - 0.23 10.4 17.4 0.11 11.4 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3995 PF13160.1 GAM28034.1 - 0.47 10.5 8.0 0.85 9.6 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3995) TCR_zetazeta PF11628.3 GAM28034.1 - 0.48 9.9 4.9 2.7 7.5 3.4 2.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain DUF3440 PF11922.3 GAM28035.1 - 0.037 13.6 0.1 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) FNIP PF05725.7 GAM28037.1 - 2.1e-57 190.7 19.8 9.8e-11 41.4 0.0 8.3 5 3 4 9 9 9 9 FNIP Repeat Methyltransf_5 PF01795.14 GAM28038.1 - 5.7e-81 272.1 0.0 3.2e-80 269.7 0.0 1.8 1 1 0 1 1 1 1 MraW methylase family Methyltransf_18 PF12847.2 GAM28038.1 - 0.013 16.0 0.0 0.26 11.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM28038.1 - 0.03 14.7 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 GAM28038.1 - 0.13 11.8 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DUF1084 PF06454.6 GAM28039.1 - 1.4e-13 50.5 14.7 2e-13 50.0 10.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1352 PF07086.7 GAM28039.1 - 0.0024 17.5 0.5 0.0024 17.5 0.4 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1352) DUF4064 PF13273.1 GAM28039.1 - 8 6.6 9.6 0.6 10.2 0.1 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF4064) Topoisom_bac PF01131.15 GAM28041.1 - 2e-97 326.5 0.0 2.5e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 GAM28041.1 - 3.3e-16 59.0 0.0 7.8e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-CHC2 PF01807.15 GAM28041.1 - 0.055 13.0 3.5 0.15 11.5 2.5 1.7 1 0 0 1 1 1 0 CHC2 zinc finger C1_1 PF00130.17 GAM28041.1 - 1.5 8.5 7.9 0.52 10.0 0.5 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EXS PF03124.9 GAM28042.1 - 4.3e-93 312.0 31.9 7e-93 311.3 22.1 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 GAM28042.1 - 2.3e-38 132.5 15.7 3.6e-23 82.7 4.8 2.2 2 0 0 2 2 2 2 SPX domain FNIP PF05725.7 GAM28043.1 - 6.4e-40 134.8 4.2 5.5e-10 39.0 0.0 5.0 3 1 3 6 6 6 5 FNIP Repeat Cyt-b5 PF00173.23 GAM28043.1 - 1.2e-22 79.4 0.2 1.7e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mucin PF01456.12 GAM28044.1 - 0.0037 17.0 27.0 0.0037 17.0 18.7 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Med3 PF11593.3 GAM28044.1 - 0.066 12.4 13.7 0.13 11.4 9.5 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.6 GAM28044.1 - 0.57 9.9 18.9 0.056 13.2 9.8 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Presenilin PF01080.12 GAM28044.1 - 1.3 7.7 3.8 6.5 5.4 3.2 1.7 2 0 0 2 2 2 0 Presenilin Coiled PF05710.7 GAM28046.1 - 8.1e-07 29.4 8.6 9.9e-07 29.1 6.0 1.2 1 0 0 1 1 1 1 Coiled coil Glyco_hydro_31 PF01055.21 GAM28047.1 - 7.7e-159 529.2 6.1 1e-158 528.8 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 GAM28047.1 - 5.3e-10 39.0 3.9 1.2e-09 37.8 0.1 3.2 3 0 0 3 3 3 1 Galactose mutarotase-like Ras PF00071.17 GAM28049.1 - 1.4e-16 60.2 0.2 3.4e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Ras family LRR_6 PF13516.1 GAM28049.1 - 1.5e-15 55.4 13.6 0.0032 17.3 0.1 6.8 7 0 0 7 7 7 5 Leucine Rich repeat Miro PF08477.8 GAM28049.1 - 2.8e-10 40.7 0.2 2.8e-10 40.7 0.2 2.5 2 1 0 2 2 2 1 Miro-like protein LRR_4 PF12799.2 GAM28049.1 - 1.3e-05 24.6 16.1 0.044 13.4 0.9 4.2 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM28049.1 - 0.00012 21.6 6.8 8.2 6.8 0.1 5.7 5 2 0 5 5 5 2 Leucine Rich Repeat Borrelia_P83 PF05262.6 GAM28049.1 - 0.0021 16.3 27.2 0.0029 15.9 18.8 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein LRR_7 PF13504.1 GAM28049.1 - 0.024 14.7 8.4 5.3 7.7 0.0 5.8 6 0 0 6 6 6 0 Leucine rich repeat LRR_8 PF13855.1 GAM28049.1 - 0.36 10.6 14.5 1.8 8.3 1.1 4.0 2 2 2 4 4 4 0 Leucine rich repeat RR_TM4-6 PF06459.7 GAM28049.1 - 0.39 10.5 23.3 0.93 9.3 16.1 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 GAM28049.1 - 2.3 8.0 22.5 4 7.3 15.6 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Parvo_coat PF00740.13 GAM28049.1 - 4.5 6.1 11.5 6.5 5.5 8.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 adh_short PF00106.20 GAM28050.1 - 1.5e-09 38.0 0.2 6.1e-08 32.7 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 GAM28050.1 - 3.9e-05 23.2 0.1 0.00014 21.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM28050.1 - 0.0018 18.2 0.0 0.003 17.6 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 GAM28050.1 - 0.0056 15.9 0.2 0.008 15.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 GAM28050.1 - 0.013 14.4 0.1 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.13 GAM28050.1 - 0.098 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_S17 PF00366.15 GAM28051.1 - 2.4e-27 94.7 1.0 3.3e-27 94.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Phage_X PF05155.10 GAM28052.1 - 0.12 12.3 1.7 4.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Phage X family FNIP PF05725.7 GAM28053.1 - 3.5e-103 337.3 30.1 8.5e-16 57.6 0.6 12.7 7 2 5 15 15 15 14 FNIP Repeat LRR_5 PF13306.1 GAM28053.1 - 0.023 14.3 0.0 0.69 9.6 0.0 3.2 3 1 0 4 4 4 0 Leucine rich repeats (6 copies) F-box-like PF12937.2 GAM28053.1 - 0.054 13.2 0.2 0.25 11.1 0.2 2.2 1 0 0 1 1 1 0 F-box-like rRNA_processing PF08524.6 GAM28054.1 - 3.7e-09 36.5 19.4 3.7e-09 36.5 13.5 3.2 2 1 0 3 3 3 1 rRNA processing Mucin PF01456.12 GAM28054.1 - 0.056 13.2 16.4 0.097 12.4 11.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PLRV_ORF5 PF01690.12 GAM28054.1 - 3.7 6.5 32.0 4.9 6.1 22.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MGC-24 PF05283.6 GAM28054.1 - 3.8 7.2 12.4 5.9 6.6 8.6 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) EB PF01683.13 GAM28055.1 - 3.8e-05 23.6 7.5 3.8e-05 23.6 5.2 4.3 2 1 2 4 4 4 4 EB module Endotoxin_N PF03945.9 GAM28056.1 - 1.2e-31 109.8 5.8 2e-31 109.1 4.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 GAM28057.1 - 8.7e-31 107.0 5.9 1.4e-30 106.3 4.1 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Ribosomal_S20p PF01649.13 GAM28057.1 - 0.31 11.4 2.0 47 4.4 0.0 3.6 3 1 0 4 4 4 0 Ribosomal protein S20 ArfGap PF01412.13 GAM28058.1 - 0.0019 17.9 0.0 0.0019 17.9 0.0 3.1 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SMC_N PF02463.14 GAM28059.1 - 2.9e-31 108.4 0.1 9.7e-31 106.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 GAM28059.1 - 2e-17 64.1 0.9 2e-17 64.1 0.6 6.3 5 1 1 6 6 6 1 AAA domain Reo_sigmaC PF04582.7 GAM28059.1 - 1.8e-05 24.0 22.5 0.0042 16.3 0.4 4.1 3 1 1 4 4 4 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 GAM28059.1 - 4.5e-05 22.8 0.0 0.00011 21.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3450 PF11932.3 GAM28059.1 - 0.00036 19.8 10.8 0.00036 19.8 7.5 5.3 2 2 2 4 4 4 1 Protein of unknown function (DUF3450) AAA_21 PF13304.1 GAM28059.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 3.8 4 0 0 4 4 4 1 AAA domain FlaC_arch PF05377.6 GAM28059.1 - 0.0084 15.9 1.0 0.0084 15.9 0.7 5.8 6 1 1 7 7 7 1 Flagella accessory protein C (FlaC) AAA_13 PF13166.1 GAM28059.1 - 0.063 11.7 75.0 0.25 9.7 6.0 5.4 5 1 1 6 6 6 0 AAA domain DUF3439 PF11921.3 GAM28059.1 - 7.2 6.3 14.9 39 4.0 7.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) WEMBL PF05701.6 GAM28059.1 - 9.8 4.5 73.6 0.025 13.0 25.7 3.8 2 2 2 4 4 4 0 Weak chloroplast movement under blue light DUF755 PF05501.6 GAM28060.1 - 1.7 8.7 11.5 2.7 8.0 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ATP-synt_E PF05680.7 GAM28060.1 - 3.5 7.6 8.2 7 6.6 5.7 1.4 1 0 0 1 1 1 0 ATP synthase E chain PA14 PF07691.7 GAM28061.1 - 8.5e-15 54.6 1.7 9.4e-15 54.5 0.3 1.7 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.13 GAM28061.1 - 6.8e-06 25.7 28.5 0.00053 19.7 0.8 11.9 12 1 0 12 12 12 7 Dictyostelium (slime mold) repeat COX4 PF02936.9 GAM28061.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV YtxH PF12732.2 GAM28061.1 - 0.086 13.2 0.1 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 YtxH-like protein MMS1_N PF10433.4 GAM28062.1 - 6.1e-75 252.2 0.4 1.1e-74 251.4 0.3 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 GAM28062.1 - 3.1e-70 236.8 2.3 2.9e-68 230.3 0.0 3.1 3 1 0 3 3 3 2 CPSF A subunit region WH1 PF00568.18 GAM28063.1 - 1.2e-16 60.3 0.3 1.7e-16 59.8 0.2 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 GAM28063.1 - 8.1e-16 58.1 0.0 8.1e-16 58.1 0.0 2.8 2 1 0 2 2 2 1 P21-Rho-binding domain DCP1 PF06058.8 GAM28063.1 - 0.001 19.0 1.0 0.0016 18.4 0.7 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family WH2 PF02205.15 GAM28063.1 - 0.024 14.2 0.1 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 WH2 motif GCS PF03074.11 GAM28064.1 - 1e-155 518.4 1.5 1.3e-155 518.0 1.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Dioxygenase_N PF04444.9 GAM28065.1 - 0.048 13.6 0.2 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Catechol dioxygenase N terminus DUF2839 PF10999.3 GAM28065.1 - 0.16 12.0 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) ATP-synt_ab PF00006.20 GAM28067.1 - 4e-46 157.2 0.0 7.2e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 GAM28067.1 - 2.9e-12 47.0 0.0 5.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 GAM28067.1 - 1.2e-08 34.9 0.7 3e-08 33.7 0.4 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF2118 PF09891.4 GAM28067.1 - 0.0014 18.3 0.0 0.005 16.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) Cation_ATPase_N PF00690.21 GAM28071.1 - 8.4e-14 50.7 0.0 1.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 GAM28072.1 - 4.2e-25 88.1 0.1 5.4e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Inhibitor_I29 PF08246.7 GAM28074.1 - 1.1e-14 54.3 2.3 2.3e-14 53.4 1.6 1.5 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF1469 PF07332.6 GAM28074.1 - 0.06 13.0 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) PH_7 PF15408.1 GAM28074.1 - 0.092 12.6 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain VSP PF03302.8 GAM28074.1 - 1.2 7.7 3.8 1.7 7.2 2.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Peptidase_C1 PF00112.18 GAM28075.1 - 7.2e-44 150.2 3.1 1.2e-43 149.4 2.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.21 GAM28075.1 - 1.5e-06 28.7 5.5 4.4e-06 27.1 3.8 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_C39_2 PF13529.1 GAM28075.1 - 0.00029 21.2 0.0 0.00079 19.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C1_2 PF03051.10 GAM28075.1 - 0.0034 15.9 1.7 0.093 11.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DnaJ PF00226.26 GAM28076.1 - 6.4e-19 67.4 0.3 6.4e-19 67.4 0.2 3.2 3 1 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.26 GAM28076.1 - 2.8e-16 59.2 1.9 5e-07 29.6 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain CoA_binding PF02629.14 GAM28077.1 - 5.6e-29 100.5 0.9 5.6e-29 100.5 0.7 2.0 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 GAM28077.1 - 2.8e-22 78.9 0.1 4.8e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 GAM28077.1 - 3.6e-09 36.3 0.0 7.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 GAM28077.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain Aminotran_1_2 PF00155.16 GAM28078.1 - 1.7e-73 247.6 0.0 2.7e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 GAM28078.1 - 1.9e-06 26.8 0.0 4.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM28078.1 - 3.1e-05 22.4 0.0 5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Flagellin_N PF00669.15 GAM28078.1 - 0.013 15.2 0.8 0.032 14.0 0.5 1.6 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region HlyU PF10115.4 GAM28078.1 - 0.021 14.6 0.9 0.1 12.4 0.3 2.2 2 0 0 2 2 2 0 Transcriptional activator HlyU NQRA PF05896.6 GAM28078.1 - 0.074 12.2 0.2 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Ras PF00071.17 GAM28079.1 - 6.8e-59 197.8 0.1 7.8e-59 197.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28079.1 - 1.3e-17 64.4 0.0 1.9e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28079.1 - 9e-13 47.8 0.1 1e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM28079.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM28079.1 - 1.5e-06 27.7 0.1 0.00014 21.3 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 GAM28079.1 - 1.1e-05 24.7 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 GAM28079.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 GAM28079.1 - 0.0017 17.8 0.1 0.093 12.2 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 GAM28079.1 - 0.0024 17.3 0.1 0.011 15.1 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 GAM28079.1 - 0.0054 16.4 0.1 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 GAM28079.1 - 0.0061 15.7 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 GAM28079.1 - 0.0089 15.7 0.1 0.017 14.8 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 GAM28079.1 - 0.0092 15.5 0.3 0.5 9.8 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 GAM28079.1 - 0.017 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.1 GAM28079.1 - 0.019 14.5 0.1 0.032 13.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 GAM28079.1 - 0.024 13.6 0.1 0.072 12.0 0.0 1.8 2 0 0 2 2 2 0 Septin SRPRB PF09439.5 GAM28079.1 - 0.029 13.6 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 GAM28079.1 - 0.034 13.6 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 GAM28079.1 - 0.04 13.6 0.1 0.095 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 GAM28079.1 - 0.076 12.6 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.7 GAM28079.1 - 0.085 12.5 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 GAM28079.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 GAM28079.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain 3Beta_HSD PF01073.14 GAM28080.1 - 1.7e-77 259.9 0.0 2.5e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 GAM28080.1 - 7.7e-36 123.6 0.0 1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 GAM28080.1 - 3.1e-16 59.0 0.2 1.7e-11 43.5 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 GAM28080.1 - 1.5e-15 57.7 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 GAM28080.1 - 1.4e-12 47.0 0.0 1.8e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 GAM28080.1 - 3.3e-07 29.5 0.0 1e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 GAM28080.1 - 1.8e-05 24.7 1.7 0.00055 19.8 1.2 2.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM28080.1 - 5e-05 23.0 0.6 0.024 14.2 0.4 2.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 GAM28080.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Lactamase_B_2 PF12706.2 GAM28080.1 - 0.078 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain LytR_cpsA_psr PF03816.9 GAM28080.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain DUF4252 PF14060.1 GAM28080.1 - 0.15 11.5 0.2 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) FNIP PF05725.7 GAM28081.1 - 1.7e-24 85.4 12.0 8.6e-06 25.6 0.2 11.1 9 3 2 11 11 11 9 FNIP Repeat SNF2_N PF00176.18 GAM28082.1 - 5.8e-79 264.9 0.0 5.8e-79 264.9 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 GAM28082.1 - 6.6e-14 51.5 0.6 1.7e-13 50.1 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 GAM28082.1 - 3.6e-07 30.0 7.3 3.6e-07 30.0 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM28082.1 - 1.1e-06 28.2 8.8 1.1e-06 28.2 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM28082.1 - 2.3e-05 24.0 6.5 2.3e-05 24.0 4.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 GAM28082.1 - 2.3e-05 24.1 8.1 2.3e-05 24.1 5.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 GAM28082.1 - 2.4e-05 24.1 4.3 2.4e-05 24.1 3.0 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 GAM28082.1 - 5.2e-05 22.8 4.9 5.2e-05 22.8 3.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM28082.1 - 7.9e-05 22.2 7.8 8.1e-05 22.2 4.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 GAM28082.1 - 0.27 10.8 5.5 0.16 11.4 0.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 GAM28082.1 - 0.51 10.1 2.9 0.39 10.5 0.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 GAM28082.1 - 1.7 8.2 11.0 0.067 12.7 2.8 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RhoGAP PF00620.22 GAM28083.1 - 9.3e-34 116.2 1.1 1.4e-33 115.6 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain Kelch_4 PF13418.1 GAM28083.1 - 2.3e-29 100.9 2.3 7.6e-12 44.8 0.0 5.1 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM28083.1 - 3.3e-25 86.8 0.2 1.8e-07 30.6 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 GAM28083.1 - 3.8e-24 83.7 2.3 2.2e-08 33.9 0.0 5.6 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 GAM28083.1 - 6.6e-23 80.0 1.2 7.7e-07 28.5 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM28083.1 - 1.7e-21 75.7 11.2 1.2e-12 47.5 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM28083.1 - 1.4e-20 72.7 0.3 1.1e-08 34.8 0.0 4.4 4 0 0 4 4 4 3 Kelch motif DUF4275 PF14101.1 GAM28083.1 - 0.015 15.3 0.2 0.19 11.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4275) RhoGAP PF00620.22 GAM28084.1 - 2.5e-35 121.3 2.7 6.9e-33 113.4 0.2 2.7 3 0 0 3 3 3 2 RhoGAP domain DEAD PF00270.24 GAM28085.1 - 5.9e-48 162.5 0.0 1.4e-47 161.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM28085.1 - 2e-26 91.6 0.0 4.1e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM28085.1 - 4.3e-06 25.7 0.0 5.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM28085.1 - 9.2e-05 22.3 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.1 GAM28086.1 - 5.4e-18 65.2 0.0 6.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM28086.1 - 2.1e-16 60.1 0.0 2.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM28086.1 - 3.5e-15 55.9 0.1 4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM28086.1 - 8.2e-14 51.8 0.0 1.1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM28086.1 - 7.7e-12 45.7 0.0 9.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM28086.1 - 7e-11 41.6 0.0 8.5e-11 41.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 GAM28086.1 - 6.1e-10 39.3 0.0 7.8e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 GAM28086.1 - 1.8e-07 30.3 0.6 6.6e-05 21.9 0.4 2.0 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_26 PF13659.1 GAM28086.1 - 2.8e-06 27.3 0.0 5.6e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 GAM28086.1 - 1.5e-05 24.4 0.0 1.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.6 GAM28086.1 - 3.4e-05 22.7 0.0 3.9e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 GAM28086.1 - 3.9e-05 23.1 0.0 4.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 GAM28086.1 - 0.00011 21.6 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 GAM28086.1 - 0.0014 17.7 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.9 GAM28086.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 GAM28086.1 - 0.0054 16.7 0.1 0.0097 15.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 GAM28086.1 - 0.013 14.5 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FmrO PF07091.6 GAM28086.1 - 0.02 13.8 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DREV PF05219.7 GAM28086.1 - 0.061 12.1 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.11 GAM28086.1 - 0.085 11.1 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M48 PF01435.13 GAM28087.1 - 1.3e-34 119.7 0.5 2.2e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Pkinase PF00069.20 GAM28088.1 - 1.5e-51 175.0 0.3 1.5e-51 175.0 0.2 2.6 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28088.1 - 2.5e-30 105.4 0.9 4.9e-30 104.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 GAM28088.1 - 0.03 14.0 0.5 0.13 11.9 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family ADIP PF11559.3 GAM28088.1 - 0.37 10.7 25.9 0.15 11.9 15.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding MACPF PF01823.14 GAM28091.1 - 1.2e-25 90.4 0.9 1.8e-25 89.9 0.7 1.2 1 0 0 1 1 1 1 MAC/Perforin domain RabGAP-TBC PF00566.13 GAM28092.1 - 8.6e-41 139.7 9.6 8.6e-41 139.7 6.6 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 GAM28092.1 - 4.1e-20 71.9 0.2 1.6e-18 66.8 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3548) Phosducin PF02114.11 GAM28093.1 - 2.7e-15 55.8 0.8 3.4e-15 55.4 0.6 1.1 1 0 0 1 1 1 1 Phosducin WD40 PF00400.27 GAM28094.1 - 9.9e-27 91.8 14.2 3.1e-12 45.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat LVIVD PF08309.6 GAM28094.1 - 0.0036 16.2 0.7 0.17 10.9 0.3 2.4 2 0 0 2 2 2 1 LVIVD repeat SSP160 PF06933.6 GAM28094.1 - 1.2 7.0 14.1 1.6 6.5 9.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SoxE PF06525.6 GAM28094.1 - 5.6 6.1 11.5 7.9 5.7 3.4 2.9 3 0 0 3 3 3 0 Sulfocyanin (SoxE) CRAL_TRIO PF00650.15 GAM28095.1 - 3.4e-42 143.6 0.1 4.9e-42 143.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM28095.1 - 2.1e-10 40.5 4.0 3.2e-10 39.9 1.9 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM28095.1 - 7e-09 35.7 0.1 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PP2C PF00481.16 GAM28097.1 - 1.3e-46 159.0 1.1 2.2e-46 158.3 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 GAM28097.1 - 0.025 14.2 0.0 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PrgI PF12666.2 GAM28097.1 - 0.084 13.0 2.5 0.16 12.0 1.7 1.4 1 0 0 1 1 1 0 PrgI family protein V_ATPase_I PF01496.14 GAM28097.1 - 8.3 4.1 7.3 12 3.5 5.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ion_trans PF00520.26 GAM28098.1 - 5e-32 110.7 62.3 3.4e-20 72.1 23.7 2.6 2 0 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.1 GAM28098.1 - 2e-07 31.0 0.1 6.4e-07 29.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM28098.1 - 1.7e-05 23.7 0.2 0.0045 16.2 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 GAM28098.1 - 0.0051 16.5 8.3 0.09 12.7 0.4 3.5 3 0 0 3 3 3 2 EF-hand domain GRP PF07172.6 GAM28098.1 - 0.013 15.9 5.6 0.013 15.9 3.9 3.2 2 0 0 2 2 2 0 Glycine rich protein family DUF2763 PF10961.3 GAM28098.1 - 0.034 14.5 5.1 0.046 14.1 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) G-7-MTase PF12803.2 GAM28098.1 - 0.32 10.0 0.0 0.32 10.0 0.0 2.6 3 0 0 3 3 3 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) La PF05383.12 GAM28099.1 - 4e-20 71.3 0.2 6.4e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 GAM28099.1 - 3.8e-05 23.5 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM28099.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM28099.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 GAM28100.1 - 5.6e-41 139.6 0.1 5.6e-41 139.6 0.1 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 GAM28100.1 - 7.5e-16 58.7 0.1 2.2e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM28100.1 - 1.4e-05 24.4 0.6 2.1e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM28100.1 - 0.0023 17.8 0.3 0.0055 16.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase E1_dh PF00676.15 GAM28100.1 - 2 7.0 6.3 3 6.4 4.4 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF3987 PF13148.1 GAM28100.1 - 2 6.8 8.4 2.7 6.4 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FKBP_C PF00254.23 GAM28101.1 - 7.9e-29 99.5 0.0 1e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Actin PF00022.14 GAM28102.1 - 1.6e-57 194.7 0.7 3e-32 111.5 0.0 2.2 2 0 0 2 2 2 2 Actin PDDEXK_1 PF12705.2 GAM28103.1 - 3.2e-08 33.2 0.0 5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 GAM28103.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF83 ABC_membrane PF00664.18 GAM28104.1 - 5.2e-120 399.9 25.6 1.1e-60 205.4 5.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM28104.1 - 1.2e-69 232.8 0.2 5.5e-34 117.4 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM28104.1 - 1.1e-14 54.1 3.2 1.4e-05 24.4 0.0 4.1 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 GAM28104.1 - 1.8e-12 47.8 1.0 0.0012 18.9 0.1 4.5 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 GAM28104.1 - 2.4e-08 33.0 1.4 0.0025 16.4 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 GAM28104.1 - 2.3e-06 27.7 0.1 0.0067 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 GAM28104.1 - 2.7e-06 27.2 1.8 0.067 13.1 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 GAM28104.1 - 3.6e-05 23.1 1.9 0.1 12.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 GAM28104.1 - 8.1e-05 21.8 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 GAM28104.1 - 0.00027 21.7 0.0 1.2 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 GAM28104.1 - 0.0018 18.5 4.6 0.48 10.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 GAM28104.1 - 0.0045 17.1 3.8 2.5 8.2 0.3 3.8 3 2 0 3 3 2 2 AAA domain UPF0081 PF03652.10 GAM28104.1 - 0.0093 16.0 0.6 0.54 10.3 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0081) Miro PF08477.8 GAM28104.1 - 0.017 15.5 0.0 5.2 7.6 0.0 3.1 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 GAM28104.1 - 0.02 14.4 0.1 5.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF1146 PF06612.6 GAM28104.1 - 0.092 12.6 0.1 0.092 12.6 0.1 3.5 4 0 0 4 4 3 0 Protein of unknown function (DUF1146) AAA_5 PF07728.9 GAM28104.1 - 0.14 11.8 1.2 29 4.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 GAM28104.1 - 0.32 10.3 3.0 13 5.1 0.1 3.3 2 2 0 2 2 2 0 AAA domain NDUF_B12 PF08122.7 GAM28104.1 - 5 6.9 5.4 2.4 7.9 0.1 2.9 3 0 0 3 3 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF2450 PF10475.4 GAM28105.1 - 8e-87 290.8 6.3 3.4e-86 288.7 4.9 1.6 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 GAM28105.1 - 1.8e-57 194.8 2.3 3.2e-57 193.9 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.9 GAM28105.1 - 0.00079 19.0 2.7 0.00079 19.0 1.9 2.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.6 GAM28105.1 - 0.0037 17.1 0.3 0.037 13.9 0.1 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Mating_N PF12731.2 GAM28105.1 - 0.0089 15.8 2.9 0.065 13.1 0.0 3.4 3 0 0 3 3 3 1 Mating-type protein beta 1 DNA_pol_A_exo1 PF01612.15 GAM28106.1 - 5.8e-18 64.9 0.0 8.5e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF1160 PF06648.6 GAM28106.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) V_ATPase_I PF01496.14 GAM28107.1 - 1.4e-264 879.5 5.5 1.6e-264 879.3 3.8 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 GAM28107.1 - 0.035 14.0 6.4 0.042 13.7 0.4 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.5 GAM28107.1 - 0.26 11.1 2.7 15 5.4 1.2 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 SPX PF03105.14 GAM28107.1 - 0.29 10.9 3.4 0.41 10.3 2.4 1.2 1 0 0 1 1 1 0 SPX domain DUF342 PF03961.8 GAM28107.1 - 0.29 9.4 4.4 0.49 8.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 GAM28107.1 - 0.53 9.2 8.4 0.92 8.4 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 GAM28107.1 - 0.84 9.1 13.0 0.47 10.0 4.1 2.9 3 0 0 3 3 3 0 IncA protein MIG-14_Wnt-bd PF06664.7 GAM28108.1 - 1.2e-51 175.2 23.7 1.6e-51 174.8 16.4 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion UPF0066 PF01980.11 GAM28109.1 - 6.8e-38 129.3 0.0 1.7e-37 128.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0066 DnaJ PF00226.26 GAM28110.1 - 1.9e-28 97.9 1.5 3.2e-28 97.2 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 GAM28110.1 - 1.4e-20 72.9 1.7 1.5e-18 66.4 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 GAM28110.1 - 3.5e-16 59.0 18.4 5.8e-16 58.2 12.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 GAM28110.1 - 0.0014 18.2 7.6 0.15 11.8 1.2 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 GAM28110.1 - 0.088 13.1 6.8 0.18 12.1 4.7 1.5 1 0 0 1 1 1 0 Cytochrome c3 Stc1 PF12898.2 GAM28110.1 - 1.9 8.6 12.0 3.5 7.7 2.3 2.4 1 1 1 2 2 2 0 Stc1 domain CLASP_N PF12348.3 GAM28111.1 - 8.4e-36 123.4 1.5 2e-35 122.2 0.2 2.0 2 0 0 2 2 2 1 CLASP N terminal Spectrin PF00435.16 GAM28111.1 - 0.034 14.4 0.1 0.25 11.6 0.0 2.4 1 1 0 1 1 1 0 Spectrin repeat V_ATPase_I PF01496.14 GAM28112.1 - 5.3e-276 917.3 0.9 6e-276 917.2 0.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HSBP1 PF06825.7 GAM28112.1 - 0.085 12.4 1.4 6.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Uds1 PF15456.1 GAM28112.1 - 3.8 7.5 8.1 0.54 10.2 2.5 1.8 2 0 0 2 2 2 0 Up-regulated During Septation DUF2236 PF09995.4 GAM28113.1 - 1.3e-11 44.2 0.0 1.8e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TIR_2 PF13676.1 GAM28114.1 - 9.6e-25 86.6 0.1 1.3e-22 79.8 0.0 2.7 2 0 0 2 2 2 1 TIR domain Ank_2 PF12796.2 GAM28114.1 - 6.8e-20 71.2 1.2 8.3e-14 51.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28114.1 - 2.7e-17 61.6 0.4 2.5e-08 33.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 GAM28114.1 - 3.5e-15 55.6 0.3 1.2e-11 44.4 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 GAM28114.1 - 5.2e-15 54.5 8.6 6.7e-08 31.9 2.7 3.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 GAM28114.1 - 5.2e-15 55.4 1.3 4.3e-09 36.6 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28114.1 - 1.6e-13 49.4 0.1 2.7e-05 23.9 0.0 5.1 5 0 0 5 5 5 2 Ankyrin repeat RCC1 PF00415.13 GAM28114.1 - 8e-11 41.9 5.2 5.6e-05 23.2 0.2 4.1 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat DUF1863 PF08937.6 GAM28114.1 - 3.1e-07 30.4 0.5 0.00013 22.0 1.1 3.8 3 1 0 3 3 3 1 MTH538 TIR-like domain (DUF1863) TIR PF01582.15 GAM28114.1 - 2.1e-06 27.2 0.0 5.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 TIR domain DUF3236 PF11576.3 GAM28114.1 - 0.036 13.4 0.0 0.095 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Vezatin PF12632.2 GAM28115.1 - 5.8e-05 22.2 2.6 5.8e-05 22.2 1.8 2.3 2 1 0 2 2 2 1 Mysoin-binding motif of peroxisomes Sigma70_ner PF04546.8 GAM28115.1 - 0.00047 19.8 3.0 0.00047 19.8 2.1 2.3 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF2457 PF10446.4 GAM28115.1 - 0.0027 16.5 18.6 0.0027 16.5 12.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 GAM28115.1 - 0.76 9.4 18.4 0.29 10.8 8.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 GAM28115.1 - 1.1 9.5 21.0 1.4 9.1 10.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 GAM28115.1 - 1.4 8.4 18.9 0.056 12.9 8.8 1.9 2 0 0 2 2 2 0 Nucleoplasmin YL1 PF05764.8 GAM28115.1 - 1.5 8.3 8.2 0.17 11.4 2.3 2.1 2 0 0 2 2 2 0 YL1 nuclear protein NOA36 PF06524.7 GAM28115.1 - 2.2 7.4 18.2 0.062 12.5 8.4 1.5 2 0 0 2 2 2 0 NOA36 protein DUF4611 PF15387.1 GAM28115.1 - 2.4 8.3 17.9 0.62 10.2 7.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Vfa1 PF08432.5 GAM28115.1 - 5.9 6.8 9.1 1 9.3 2.9 2.2 2 1 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 PseudoU_synth_1 PF01416.15 GAM28116.1 - 3.2e-26 91.7 0.0 5.2e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase Baculo_LEF5 PF04838.7 GAM28117.1 - 0.2 11.3 2.6 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 KIAA1430 PF13879.1 GAM28117.1 - 6.6 7.2 13.8 0.84 10.1 2.2 3.1 2 1 1 3 3 3 0 KIAA1430 homologue Arf PF00025.16 GAM28118.1 - 2.5e-76 254.7 0.1 2.9e-76 254.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM28118.1 - 1.4e-14 53.6 0.0 1.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAM28118.1 - 1.2e-12 47.2 1.7 1.5e-09 37.0 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 GAM28118.1 - 2.2e-12 46.6 0.0 2.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 GAM28118.1 - 6.6e-12 45.0 0.0 8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM28118.1 - 1.7e-07 31.7 0.0 2.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM28118.1 - 1.7e-05 24.7 0.0 2.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAM28118.1 - 0.0012 17.9 0.7 0.0039 16.2 0.3 2.0 1 1 1 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 GAM28118.1 - 0.0016 17.8 0.2 0.012 15.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Eno-Rase_FAD_bd PF07055.7 GAM28118.1 - 0.075 12.9 0.4 9.5 6.2 0.2 2.5 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain AAA_33 PF13671.1 GAM28118.1 - 0.081 12.7 0.1 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.2 GAM28120.1 - 0.022 15.0 1.9 3.5 8.0 0.0 3.3 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28120.1 - 0.053 13.7 3.3 47 4.6 0.0 5.8 8 0 0 8 8 8 0 Ankyrin repeat G-alpha PF00503.15 GAM28120.1 - 0.057 12.1 0.1 0.085 11.5 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF2935 PF11155.3 GAM28122.1 - 0.005 16.9 2.0 0.021 14.9 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2935) EF-hand_2 PF09068.6 GAM28122.1 - 0.0059 16.6 0.4 0.014 15.4 0.2 1.6 1 0 0 1 1 1 1 EF hand SLT_2 PF13406.1 GAM28122.1 - 0.02 13.7 1.5 0.27 10.1 0.2 2.1 2 0 0 2 2 2 0 Transglycosylase SLT domain DUF948 PF06103.6 GAM28122.1 - 0.035 13.9 2.5 1.2 8.9 1.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TerB PF05099.8 GAM28122.1 - 0.066 12.9 0.7 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TerB Med15_fungi PF05397.7 GAM28122.1 - 0.16 11.9 3.3 0.11 12.4 0.4 2.2 2 1 1 3 3 3 0 Mediator complex subunit 15 Flagellin_C PF00700.16 GAM28122.1 - 0.43 10.7 3.0 1.3 9.2 1.5 2.1 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region AAT PF03417.11 GAM28123.1 - 0.026 13.9 0.8 0.026 13.9 0.5 1.6 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Asp_protease_2 PF13650.1 GAM28124.1 - 1.4e-06 28.7 2.0 2.8e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Aspartyl protease RVP PF00077.15 GAM28124.1 - 0.00094 19.0 0.2 0.00094 19.0 0.2 2.6 2 1 1 3 3 3 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 GAM28124.1 - 0.0036 17.0 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease GAGA_bind PF06217.7 GAM28124.1 - 6.4 6.6 15.0 9.8 6.0 10.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Nop53 PF07767.6 GAM28125.1 - 0.0014 17.7 6.3 0.0015 17.6 4.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.5 GAM28125.1 - 0.019 15.2 1.7 0.023 14.9 1.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_RNA_Pol_19 PF05320.7 GAM28125.1 - 0.028 14.1 6.7 0.035 13.8 4.6 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Prothymosin PF03247.9 GAM28125.1 - 0.12 12.4 13.0 0.19 11.8 9.0 1.4 1 1 0 1 1 1 0 Prothymosin/parathymosin family CDC45 PF02724.9 GAM28125.1 - 0.33 8.9 6.7 0.36 8.8 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 GAM28125.1 - 0.34 10.4 10.6 0.35 10.4 7.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.7 GAM28125.1 - 1.3 8.0 9.6 1.5 7.8 6.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ndc1_Nup PF09531.5 GAM28125.1 - 2.1 6.6 4.8 2.2 6.6 3.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Vfa1 PF08432.5 GAM28125.1 - 2.6 8.0 11.0 2.7 7.9 7.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PLDc_2 PF13091.1 GAM28126.1 - 6.1e-21 74.4 0.0 4e-16 58.9 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM28126.1 - 2.1e-05 24.1 0.4 0.029 14.1 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif Ribosomal_L9_N PF01281.14 GAM28127.1 - 1e-16 59.8 0.0 2.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 GAM28127.1 - 0.0025 17.8 0.1 0.0043 17.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Stimulus_sens_1 PF13756.1 GAM28127.1 - 0.13 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Stimulus-sensing domain Peptidase_C54 PF03416.14 GAM28128.1 - 1.9e-88 296.2 0.0 2.6e-88 295.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 GAM28128.1 - 0.00049 19.2 0.0 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase family C78 ADP_PFK_GK PF04587.10 GAM28129.1 - 4.7e-74 249.2 0.0 6.6e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region Nitro_FeMo-Co PF02579.12 GAM28129.1 - 0.016 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor PDEase_II PF02112.10 GAM28130.1 - 1e-84 284.3 0.8 1.3e-84 284.0 0.6 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 GAM28130.1 - 4.6e-06 26.3 0.1 1.8e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain LRR_6 PF13516.1 GAM28131.1 - 5.5e-11 41.3 37.5 0.019 14.9 0.0 12.5 12 0 0 12 12 12 4 Leucine Rich repeat LRR_1 PF00560.28 GAM28131.1 - 9.6e-09 34.0 34.3 1.4 9.2 0.0 13.0 13 0 0 13 13 13 3 Leucine Rich Repeat LRR_4 PF12799.2 GAM28131.1 - 1.9e-07 30.5 39.3 0.0084 15.7 0.1 8.4 4 3 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM28131.1 - 1.5e-06 27.8 36.5 0.027 14.2 1.1 7.9 5 1 3 8 8 8 4 Leucine rich repeat LRR_7 PF13504.1 GAM28131.1 - 1.7e-06 27.2 20.6 12 6.6 0.4 10.1 10 0 0 10 10 10 2 Leucine rich repeat ABC_tran PF00005.22 GAM28132.1 - 4.3e-43 146.8 3.7 7.1e-21 74.9 0.0 3.4 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 GAM28132.1 - 1.5e-13 51.3 5.8 0.0048 16.8 0.2 4.4 3 1 1 4 4 4 4 AAA domain AAA_17 PF13207.1 GAM28132.1 - 3.8e-09 37.3 4.5 0.0039 17.9 0.0 4.3 4 1 0 4 4 3 2 AAA domain ABC_tran_2 PF12848.2 GAM28132.1 - 4.5e-08 32.8 0.4 4.5e-08 32.8 0.2 3.1 3 0 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 GAM28132.1 - 8.6e-08 32.5 4.5 0.12 12.7 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_15 PF13175.1 GAM28132.1 - 1.6e-07 30.7 7.9 0.023 13.7 1.5 4.3 2 1 2 5 5 5 2 AAA ATPase domain Miro PF08477.8 GAM28132.1 - 1.8e-07 31.6 0.1 0.016 15.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 GAM28132.1 - 2.3e-07 30.6 0.1 0.0085 15.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 GAM28132.1 - 2.4e-07 30.9 0.6 0.0055 16.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 GAM28132.1 - 4.7e-07 30.0 0.1 0.023 14.9 0.1 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 GAM28132.1 - 1.1e-06 27.9 1.3 0.029 13.6 0.0 3.6 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 GAM28132.1 - 1.3e-06 28.1 0.3 0.023 14.4 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 GAM28132.1 - 7.6e-06 25.1 0.2 0.029 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM28132.1 - 9.9e-06 24.9 0.2 0.047 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 GAM28132.1 - 1.6e-05 24.4 0.0 0.041 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 GAM28132.1 - 1.6e-05 24.8 0.1 0.43 10.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 GAM28132.1 - 2.2e-05 24.4 6.0 0.025 14.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 GAM28132.1 - 7.5e-05 22.4 0.2 0.84 9.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 GAM28132.1 - 8.5e-05 22.0 2.6 0.21 11.0 0.0 3.2 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 GAM28132.1 - 0.00011 22.2 5.3 0.077 12.9 0.3 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 GAM28132.1 - 0.00011 22.0 0.6 0.21 11.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 GAM28132.1 - 0.00015 21.6 2.3 0.24 11.3 0.1 3.4 4 1 0 4 4 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 GAM28132.1 - 0.00017 21.9 10.2 0.055 13.7 0.0 4.0 4 1 0 4 4 4 2 AAA domain Arch_ATPase PF01637.13 GAM28132.1 - 0.00028 20.6 0.0 0.24 11.0 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 GAM28132.1 - 0.00044 20.3 0.0 0.33 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 GAM28132.1 - 0.00052 19.4 1.8 0.2 11.0 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 GAM28132.1 - 0.00072 19.2 0.1 0.23 11.1 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 GAM28132.1 - 0.00079 19.1 0.0 0.35 10.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 GAM28132.1 - 0.00081 18.9 0.9 2.5 7.4 0.1 3.4 3 0 0 3 3 3 2 AAA-like domain NB-ARC PF00931.17 GAM28132.1 - 0.0011 17.9 0.1 1 8.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.1 GAM28132.1 - 0.0018 17.8 0.2 2 7.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 GAM28132.1 - 0.0033 16.3 0.1 1.8 7.4 0.1 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein FeoB_N PF02421.13 GAM28132.1 - 0.0054 16.0 0.3 1.1 8.5 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF3584 PF12128.3 GAM28132.1 - 0.0064 13.8 0.1 0.0064 13.8 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) SbcCD_C PF13558.1 GAM28132.1 - 0.0091 15.8 0.0 1.3 8.9 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 GAM28132.1 - 0.011 15.1 2.4 1.2 8.5 0.1 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 GAM28132.1 - 0.022 14.3 0.8 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 GAM28132.1 - 0.049 12.9 2.4 0.58 9.4 0.1 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein PWI PF01480.12 GAM28132.1 - 0.05 13.7 0.1 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 PWI domain AAA_13 PF13166.1 GAM28132.1 - 0.085 11.3 8.6 0.084 11.3 0.1 3.3 2 1 1 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 GAM28132.1 - 0.12 11.8 0.0 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 GAM28132.1 - 0.14 11.7 4.3 4.9 6.6 0.0 2.9 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.12 GAM28132.1 - 0.44 10.3 10.9 0.76 9.5 0.1 4.0 3 1 1 4 4 4 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 GAM28132.1 - 2.2 8.0 5.9 15 5.3 0.1 3.3 4 0 0 4 4 2 0 Dynamin family Acetyltransf_9 PF13527.1 GAM28133.1 - 1.2e-25 89.8 0.1 2.2e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM28133.1 - 3.7e-06 26.9 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 GAM28133.1 - 0.00015 21.7 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 GAM28133.1 - 0.0025 18.0 0.1 0.045 13.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM28133.1 - 0.012 15.7 0.0 0.097 12.8 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM28133.1 - 0.024 14.4 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 GAM28133.1 - 0.043 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Redoxin PF08534.5 GAM28134.1 - 1e-31 109.4 0.0 1.1e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 GAM28134.1 - 7.2e-13 48.3 0.0 8.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Rap_GAP PF02145.10 GAM28135.1 - 2.4e-44 150.9 0.0 5.1e-44 149.8 0.0 1.5 1 1 0 1 1 1 1 Rap/ran-GAP Toxin_25 PF08095.6 GAM28135.1 - 0.28 10.9 1.7 0.89 9.3 1.2 1.8 1 0 0 1 1 1 0 Hefutoxin family Kinesin PF00225.18 GAM28136.1 - 3.2e-107 358.1 0.0 3.2e-107 358.1 0.0 3.1 3 1 1 4 4 4 1 Kinesin motor domain WD40 PF00400.27 GAM28136.1 - 1.3e-35 119.9 21.6 4.2e-07 29.6 0.4 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat EF-hand_1 PF00036.27 GAM28137.1 - 7.2e-12 43.7 2.4 1.6e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 GAM28137.1 - 1.1e-09 38.2 0.4 1.6e-09 37.7 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 GAM28137.1 - 4.3e-08 32.3 0.2 0.00028 20.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 GAM28137.1 - 3.5e-07 29.7 0.5 6.3e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 GAM28137.1 - 0.0031 16.8 0.2 0.18 11.2 0.0 2.5 2 0 0 2 2 2 1 EF hand ATP-synt_E_2 PF08112.6 GAM28137.1 - 5.9 7.0 6.5 43 4.2 0.1 3.5 4 0 0 4 4 4 0 ATP synthase epsilon subunit TMA7 PF09072.5 GAM28138.1 - 2e-27 95.4 21.1 2.2e-27 95.2 14.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 PBP PF01161.15 GAM28139.1 - 1.1e-28 99.9 1.1 1.3e-28 99.6 0.8 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GDPD PF03009.12 GAM28140.1 - 2.9e-56 190.8 0.0 6.6e-56 189.6 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 GAM28140.1 - 9.9e-41 137.9 3.3 2.9e-21 75.5 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28140.1 - 5.8e-37 125.4 0.5 3.7e-07 30.4 0.0 6.0 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM28140.1 - 1.3e-35 119.4 0.0 2.7e-07 30.0 0.0 8.6 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 GAM28140.1 - 1.4e-33 111.5 1.1 5.4e-06 26.1 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 GAM28140.1 - 1.5e-31 107.6 0.3 3e-10 40.0 0.0 6.7 4 2 2 6 6 6 6 Ankyrin repeats (many copies) CBM_20 PF00686.14 GAM28140.1 - 6.9e-16 57.6 0.0 1.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain SPX PF03105.14 GAM28140.1 - 3.2e-07 30.4 8.2 1.9e-06 27.8 0.5 3.1 2 1 0 2 2 2 1 SPX domain UQ_con PF00179.21 GAM28141.1 - 5.2e-13 48.6 0.1 6.2e-13 48.3 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme SR-25 PF10500.4 GAM28141.1 - 0.02 14.3 8.9 0.027 13.9 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vma12 PF11712.3 GAM28141.1 - 0.062 12.9 0.1 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RWD PF05773.17 GAM28141.1 - 0.094 12.6 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 RWD domain PB1 PF00564.19 GAM28142.1 - 3.4e-16 58.6 0.1 5.4e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.12 GAM28142.1 - 1.4e-12 46.9 6.6 3e-12 45.8 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type AUX_IAA PF02309.11 GAM28142.1 - 0.73 9.5 7.7 0.43 10.2 0.0 3.2 3 1 0 3 3 3 0 AUX/IAA family PNP_UDP_1 PF01048.15 GAM28144.1 - 3.9e-31 107.8 0.2 4.6e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily ERCC4 PF02732.10 GAM28145.1 - 1.5e-20 73.3 0.0 7.6e-20 71.1 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain LRR_4 PF12799.2 GAM28146.1 - 1.3e-44 149.1 44.8 2.3e-11 43.0 1.7 7.3 6 1 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM28146.1 - 6.8e-27 93.0 34.0 1.6e-10 40.5 3.5 5.5 4 1 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.1 GAM28146.1 - 1.7e-17 63.5 22.6 1.2e-07 31.4 0.4 4.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 GAM28146.1 - 3e-15 53.6 27.4 0.18 12.1 0.0 11.3 10 1 1 11 11 11 6 Leucine rich repeat LRR_1 PF00560.28 GAM28146.1 - 5e-14 50.1 40.7 0.18 11.9 0.3 11.0 10 1 1 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.1 GAM28146.1 - 2.8e-13 48.4 39.9 0.0025 17.7 0.2 11.1 9 3 3 12 12 12 6 Leucine Rich repeat LRR_2 PF07723.8 GAM28146.1 - 0.058 13.9 3.0 47 4.7 0.0 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat E2F_TDP PF02319.15 GAM28147.1 - 3.8e-11 42.3 0.2 3e-05 23.5 0.1 2.8 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain Med15 PF09606.5 GAM28147.1 - 0.59 8.2 84.7 0.77 7.8 58.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Proteasome PF00227.21 GAM28148.1 - 4e-61 205.6 0.2 8.2e-61 204.6 0.1 1.5 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM28148.1 - 3.6e-10 38.9 0.1 2.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DRMBL PF07522.9 GAM28149.1 - 3.7e-26 91.3 0.1 1e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 GAM28149.1 - 2.4e-07 30.4 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM28149.1 - 0.00013 21.7 0.2 0.00024 20.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 GAM28149.1 - 0.056 13.2 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase CBM49 PF09478.5 GAM28150.1 - 1.9e-07 31.0 0.3 5.4e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 MRP-L27 PF09809.4 GAM28151.1 - 1.8e-09 37.1 0.1 1.9e-09 37.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 PH PF00169.24 GAM28152.1 - 7.8e-12 45.3 0.4 7.8e-12 45.3 0.3 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM28152.1 - 2.1e-08 34.3 9.3 4.2e-08 33.4 2.9 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM28152.1 - 3.1e-06 27.1 0.4 0.058 13.4 0.1 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 GAM28152.1 - 0.00011 22.0 0.8 1.7 8.5 0.3 4.0 3 1 0 4 4 4 2 PH domain Mcp5_PH PF12814.2 GAM28152.1 - 0.0021 17.9 1.2 0.74 9.7 0.0 2.8 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology YejG PF13989.1 GAM28153.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.4 1 1 0 1 1 1 0 YejG-like protein Ank_2 PF12796.2 GAM28155.1 - 0.00032 20.9 3.9 0.7 10.2 2.7 4.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28155.1 - 0.0018 18.3 0.1 3.5 8.1 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.3 GAM28155.1 - 0.053 13.3 2.1 4.3 7.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) Ank_5 PF13857.1 GAM28155.1 - 0.082 13.1 0.0 7.3 6.9 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Y_Y_Y PF07495.8 GAM28157.1 - 0.00085 19.0 5.7 0.84 9.4 0.1 3.7 3 0 0 3 3 3 2 Y_Y_Y domain Herpes_UL52 PF03121.10 GAM28157.1 - 0.11 12.2 0.2 16 5.3 0.0 3.8 5 0 0 5 5 5 0 Herpesviridae UL52/UL70 DNA primase Colipase PF01114.13 GAM28157.1 - 0.37 10.3 1.3 9.3 5.8 0.0 3.1 4 0 0 4 4 4 0 Colipase, N-terminal domain Big_3_4 PF13754.1 GAM28157.1 - 0.52 10.6 6.6 32 4.9 0.1 3.7 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Ank_2 PF12796.2 GAM28158.1 - 2.4e-27 95.0 14.7 0.013 15.8 0.0 15.9 9 7 2 11 11 11 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28158.1 - 7.7e-10 38.6 25.4 2.5 8.4 0.1 14.4 16 1 0 16 16 16 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28158.1 - 2.2e-07 30.4 27.6 4.2 7.8 0.1 15.7 19 0 0 19 19 19 1 Ankyrin repeat Ank_4 PF13637.1 GAM28158.1 - 5.9e-05 23.4 25.1 2.2 8.9 0.0 13.9 16 3 4 20 20 20 2 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.6 GAM28158.1 - 0.00036 20.6 2.6 0.18 11.9 0.1 4.4 4 0 0 4 4 4 1 Phage T7 capsid assembly protein Ank PF00023.25 GAM28158.1 - 2.6 8.0 28.6 36 4.3 0.1 12.5 15 0 0 15 15 15 0 Ankyrin repeat Glyco_hydro_18 PF00704.23 GAM28159.1 - 5.7e-52 177.2 1.1 8.9e-52 176.6 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 GAM28159.1 - 2.4e-15 56.1 0.3 2.9e-08 33.4 0.0 3.8 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.14 GAM28159.1 - 3.6e-07 30.0 7.8 3.6e-07 30.0 5.4 3.6 4 0 0 4 4 4 1 Chitin recognition protein DUF3142 PF11340.3 GAM28159.1 - 0.00069 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF3902 PF13042.1 GAM28159.1 - 0.026 13.8 2.5 0.045 13.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) FNIP PF05725.7 GAM28162.1 - 1.7e-59 197.4 9.6 4.1e-17 61.8 0.0 7.1 2 2 5 8 8 8 8 FNIP Repeat Glyco_hydro_18 PF00704.23 GAM28163.1 - 3e-70 237.3 6.7 3.8e-70 237.0 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4232 PF14016.1 GAM28163.1 - 0.032 13.8 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) DUF4557 PF15101.1 GAM28166.1 - 0.069 12.9 9.8 0.074 12.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 GAM28166.1 - 0.12 10.6 22.6 0.12 10.5 15.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 GAM28166.1 - 0.13 11.7 4.8 0.14 11.6 3.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 GAM28166.1 - 0.31 11.0 12.9 0.45 10.5 9.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 GAM28166.1 - 0.78 7.8 30.8 0.92 7.6 21.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 GAM28166.1 - 1.8 6.1 23.3 2.2 5.8 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3464 PF11947.3 GAM28166.1 - 1.8 7.9 5.0 2.5 7.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) EIF4E-T PF10477.4 GAM28166.1 - 2.2 6.9 9.6 2.4 6.8 6.6 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Activator_LAG-3 PF11498.3 GAM28166.1 - 5.9 5.5 35.0 7.5 5.1 24.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TBCA PF02970.11 GAM28167.1 - 3.7e-20 71.7 10.2 5.1e-20 71.3 7.1 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A ApoO PF09769.4 GAM28167.1 - 0.035 13.8 0.6 0.05 13.3 0.3 1.3 1 1 0 1 1 1 0 Apolipoprotein O IncA PF04156.9 GAM28167.1 - 0.09 12.3 9.5 0.11 12.0 6.6 1.1 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 GAM28167.1 - 0.13 10.6 7.2 0.15 10.4 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ImpA-rel_N PF06812.7 GAM28167.1 - 0.13 12.0 0.0 9.5 6.0 0.0 2.2 1 1 1 2 2 2 0 ImpA-related N-terminal DASH_Dad4 PF08650.5 GAM28167.1 - 0.16 11.8 1.7 0.3 11.0 0.3 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad4 CorA PF01544.13 GAM28167.1 - 0.25 10.3 4.2 0.27 10.2 2.3 1.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein BLOC1_2 PF10046.4 GAM28167.1 - 0.45 10.6 8.4 0.084 13.0 2.1 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Complex1_LYR_2 PF13233.1 GAM28167.1 - 0.54 10.7 3.2 1.1 9.7 2.2 1.6 1 1 0 1 1 1 0 Complex1_LYR-like DUF2205 PF10224.4 GAM28167.1 - 0.54 9.8 8.1 0.81 9.3 1.4 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 GAM28167.1 - 0.6 10.4 9.2 2 8.7 5.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3552 PF12072.3 GAM28167.1 - 0.65 9.1 10.9 0.79 8.8 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Laps PF10169.4 GAM28167.1 - 0.82 9.9 6.6 0.62 10.3 3.7 1.4 1 1 0 1 1 1 0 Learning-associated protein DUF4164 PF13747.1 GAM28167.1 - 1.1 9.4 5.8 0.41 10.8 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DASH_Dam1 PF08653.5 GAM28167.1 - 1.1 9.0 4.1 0.23 11.2 0.2 1.9 3 0 0 3 3 2 0 DASH complex subunit Dam1 Troponin PF00992.15 GAM28167.1 - 1.8 8.6 10.2 2 8.4 5.4 1.9 1 1 1 2 2 2 0 Troponin NEMO PF11577.3 GAM28167.1 - 2.4 7.9 7.6 1.5 8.5 1.3 2.5 2 1 0 2 2 2 0 NF-kappa-B essential modulator NEMO Spb1_C PF07780.7 GAM28168.1 - 1e-62 211.4 28.0 1e-62 211.4 19.4 4.2 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 GAM28168.1 - 5.1e-55 186.2 0.0 1e-54 185.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 GAM28168.1 - 9.6e-35 119.4 16.5 9.6e-35 119.4 11.5 6.2 2 1 5 7 7 7 1 Domain of unknown function (DUF3381) DUF4537 PF15057.1 GAM28170.1 - 0.00052 19.7 0.4 0.011 15.4 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Ank_2 PF12796.2 GAM28171.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Peptidase_C48 PF02902.14 GAM28173.1 - 0.00025 20.7 0.0 0.00069 19.2 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LUC7 PF03194.10 GAM28173.1 - 0.49 9.8 14.8 0.23 10.9 8.4 1.7 2 0 0 2 2 2 0 LUC7 N_terminus Bul1_C PF04426.7 GAM28174.1 - 0.00068 18.9 1.6 0.00091 18.4 0.8 1.4 1 1 0 1 1 1 1 Bul1 C terminus FolB PF02152.13 GAM28174.1 - 0.02 15.0 0.9 0.038 14.1 0.6 1.6 1 0 0 1 1 1 0 Dihydroneopterin aldolase Tet_JBP PF12851.2 GAM28174.1 - 0.11 11.7 0.4 0.18 11.1 0.2 1.4 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily HNH_5 PF14279.1 GAM28175.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease CRISPR_Cas2 PF09827.4 GAM28176.1 - 0.0068 16.5 0.1 0.028 14.5 0.0 2.1 2 1 1 3 3 3 1 CRISPR associated protein Cas2 DUF2457 PF10446.4 GAM28176.1 - 2.2 6.9 12.1 2.7 6.6 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 GAM28176.1 - 5.1 6.6 9.5 6.7 6.2 6.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin DNA_pol_B_2 PF03175.8 GAM28177.1 - 0.0024 16.6 1.2 0.048 12.3 0.9 2.2 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Ank_2 PF12796.2 GAM28178.1 - 9.4e-12 45.1 5.4 1.8e-08 34.5 0.2 5.5 4 2 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28178.1 - 8e-07 28.7 14.9 0.094 13.0 0.0 8.7 10 0 0 10 10 10 2 Ankyrin repeat Ank_5 PF13857.1 GAM28178.1 - 1.2e-05 25.3 9.3 8.7 6.7 0.0 7.5 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM28178.1 - 5.3e-05 22.8 12.0 3.4 7.6 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.1 GAM28178.1 - 0.00084 19.7 10.0 2.1 8.9 0.1 6.4 7 0 0 7 7 7 1 Ankyrin repeats (many copies) UAF_Rrn10 PF05234.6 GAM28179.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Ank_2 PF12796.2 GAM28180.1 - 3.7e-20 72.0 13.4 7.8e-05 22.9 0.2 10.1 7 3 2 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28180.1 - 3.9e-05 23.4 18.1 4.1 7.9 0.1 10.6 11 1 1 12 12 12 3 Ankyrin repeat Ank_5 PF13857.1 GAM28180.1 - 8.3e-05 22.7 12.1 7.7 6.9 0.3 8.9 8 2 2 10 10 10 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM28180.1 - 0.15 12.6 16.3 64 4.2 0.0 9.6 13 1 0 13 13 13 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM28180.1 - 0.45 10.4 18.8 12 5.8 0.1 9.0 12 0 0 12 12 12 0 Ankyrin repeat TPR_19 PF14559.1 GAM28181.1 - 9.7e-12 45.0 0.0 0.069 13.4 0.0 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 GAM28181.1 - 2.9e-10 39.6 0.1 0.0061 16.1 0.0 5.7 7 1 1 8 8 8 2 TPR repeat TPR_16 PF13432.1 GAM28181.1 - 3.4e-08 33.9 0.0 0.088 13.5 0.0 6.1 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM28181.1 - 4.5e-08 33.0 0.0 0.11 13.1 0.0 7.3 7 2 2 9 9 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM28181.1 - 8.5e-08 32.0 0.3 0.016 15.1 0.1 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM28181.1 - 6e-06 25.6 0.0 0.038 13.6 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM28181.1 - 7.9e-06 25.6 0.0 0.84 9.9 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM28181.1 - 2.2e-05 23.9 1.0 1 9.4 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM28181.1 - 2.5e-05 23.7 0.0 0.065 13.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 GAM28181.1 - 0.00011 22.2 0.0 1.3 9.2 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 GAM28181.1 - 0.00024 21.3 0.3 45 4.8 0.0 6.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 GAM28181.1 - 0.031 14.6 0.0 67 4.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 GAM28181.1 - 0.031 14.1 0.1 40 4.3 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Fibrillarin_2 PF10113.4 GAM28182.1 - 0.05 11.9 0.1 0.087 11.1 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein CENP-O PF09496.5 GAM28182.1 - 3.1 8.0 6.0 1.6 9.0 1.9 2.2 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component MMR_HSR1_C PF08438.5 GAM28183.1 - 1e-33 115.7 0.1 1.7e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 GAM28183.1 - 2.6e-18 66.0 0.0 7.2e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM28183.1 - 2.1e-10 40.0 0.5 1.7e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B TGS PF02824.16 GAM28183.1 - 0.0037 17.0 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.18 GAM28183.1 - 0.033 14.0 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 Dynamin family YchF-GTPase_C PF06071.8 GAM28183.1 - 0.065 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF933) ATP_bind_1 PF03029.12 GAM28183.1 - 0.11 12.0 0.5 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 GAM28183.1 - 0.13 12.7 0.1 1.2 9.6 0.0 2.5 3 0 0 3 3 3 0 Miro-like protein DUF2018 PF09442.5 GAM28185.1 - 0.033 14.7 0.4 0.088 13.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Adeno_E3_CR2 PF02439.10 GAM28186.1 - 0.0044 16.5 1.8 0.0089 15.5 1.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Beta_helix PF13229.1 GAM28186.1 - 5.5 6.7 58.8 1.3 8.7 1.7 3.5 1 1 0 2 2 2 0 Right handed beta helix region Ank_2 PF12796.2 GAM28187.1 - 1.5e-07 31.6 2.2 3.8 7.9 0.0 6.6 4 2 0 4 4 4 3 Ankyrin repeats (3 copies) RSS_P20 PF11757.3 GAM28187.1 - 0.0036 17.4 0.1 0.011 15.8 0.1 1.8 1 0 0 1 1 1 1 Suppressor of RNA silencing P21-like Ank_3 PF13606.1 GAM28187.1 - 0.0045 17.0 8.5 29 5.2 0.1 8.1 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.1 GAM28187.1 - 0.0086 16.3 1.6 71 3.8 0.0 6.6 7 0 0 7 7 7 0 Ankyrin repeats (many copies) DUF1539 PF07560.6 GAM28187.1 - 3.2 7.6 9.0 9.1 6.1 0.2 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1539) Ank_2 PF12796.2 GAM28188.1 - 1.2e-05 25.5 0.2 0.8 10.0 0.1 5.9 5 2 0 5 5 5 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28188.1 - 0.00037 20.4 2.7 0.53 10.6 0.0 6.6 6 1 1 7 7 7 1 Ankyrin repeat Ank PF00023.25 GAM28188.1 - 2.7 7.9 5.4 13 5.7 0.1 4.7 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.2 GAM28189.1 - 7.6e-30 103.0 11.0 0.0021 18.3 0.2 13.3 7 4 4 11 11 11 9 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28189.1 - 7e-11 42.0 1.9 5.5 7.3 0.0 12.4 14 1 0 14 14 14 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28189.1 - 1.5e-06 27.8 23.4 8.9 6.8 0.0 15.4 18 0 0 18 18 18 2 Ankyrin repeat Ank_4 PF13637.1 GAM28189.1 - 4.8e-06 26.9 18.8 0.72 10.4 0.0 13.4 15 3 2 17 17 17 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM28189.1 - 0.00032 20.3 25.7 25 4.9 0.0 14.3 20 0 0 20 20 20 0 Ankyrin repeat PPR_3 PF13812.1 GAM28189.1 - 0.069 13.4 1.4 17 5.9 0.0 5.0 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Ank_2 PF12796.2 GAM28190.1 - 0.00011 22.4 0.5 1.6 9.0 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) CHIPS PF11434.3 GAM28190.1 - 0.041 13.5 0.1 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Ank_3 PF13606.1 GAM28190.1 - 0.061 13.5 0.6 37 4.9 0.0 5.2 6 0 0 6 6 6 0 Ankyrin repeat DUF3447 PF11929.3 GAM28190.1 - 1.2 8.9 5.1 5.2 6.9 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DDE_Tnp_4 PF13359.1 GAM28191.1 - 1.6e-22 79.8 0.5 3.3e-21 75.5 0.4 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM28191.1 - 8e-09 35.3 0.9 1.2e-08 34.7 0.6 1.3 1 0 0 1 1 1 1 Transposase DDE domain Ank_2 PF12796.2 GAM28192.1 - 6.3e-09 36.0 0.7 3.3e-05 24.1 0.1 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28192.1 - 6.7e-06 25.8 3.7 0.3 11.4 0.0 5.2 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.1 GAM28192.1 - 0.00038 20.8 2.4 25 5.5 0.0 5.6 6 1 0 6 6 6 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28192.1 - 0.0037 17.4 1.3 1.7 8.9 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF3734 PF12536.3 GAM28192.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Patatin phospholipase Ank PF00023.25 GAM28192.1 - 0.028 14.2 5.6 17 5.4 0.2 4.8 5 0 0 5 5 5 0 Ankyrin repeat Ank_2 PF12796.2 GAM28193.1 - 0.0055 17.0 0.3 0.088 13.1 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) DUF1572 PF07609.6 GAM28196.1 - 0.073 12.6 0.1 0.7 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Ank_2 PF12796.2 GAM28198.1 - 3.3e-10 40.1 0.3 0.031 14.6 0.0 4.9 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28198.1 - 0.00063 19.7 3.6 39 4.9 0.0 6.4 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.1 GAM28198.1 - 0.002 18.2 0.0 45 4.4 0.0 4.9 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM28198.1 - 0.018 15.5 2.7 1.2e+02 3.3 0.0 6.0 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM28199.1 - 6.2e-14 52.1 14.4 0.012 15.9 0.0 10.0 5 3 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28199.1 - 0.00078 19.6 11.2 0.26 11.5 0.0 7.3 9 1 0 9 9 9 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28199.1 - 0.0015 18.6 14.5 21 5.7 0.0 10.3 13 0 0 13 13 13 1 Ankyrin repeat Ank_4 PF13637.1 GAM28199.1 - 0.0022 18.4 9.2 55 4.4 0.0 8.6 9 0 0 9 9 9 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM28199.1 - 0.097 12.5 13.5 35 4.4 0.0 8.6 11 0 0 11 11 11 0 Ankyrin repeat Spp-24 PF07448.6 GAM28200.1 - 0.013 15.4 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) Ank_4 PF13637.1 GAM28200.1 - 0.018 15.5 0.2 0.21 12.1 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM28201.1 - 1.3e-15 57.4 7.3 0.0049 17.1 1.4 7.4 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28201.1 - 4.2e-08 33.1 1.0 2.4 8.5 0.0 7.9 7 1 1 8 8 8 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28201.1 - 1.3e-05 24.9 11.7 2.5 8.5 0.0 9.9 12 0 0 12 12 12 1 Ankyrin repeat Ank PF00023.25 GAM28201.1 - 6.5e-05 22.5 18.3 6 6.8 0.0 10.0 12 0 0 12 12 12 2 Ankyrin repeat Ank_4 PF13637.1 GAM28201.1 - 0.0024 18.3 6.7 33 5.1 0.0 7.0 7 1 2 9 9 9 0 Ankyrin repeats (many copies) HTH_40 PF14493.1 GAM28201.1 - 0.0026 17.9 2.0 7.1 6.9 0.0 4.1 2 1 1 3 3 3 1 Helix-turn-helix domain DUF3447 PF11929.3 GAM28201.1 - 1.7 8.4 19.8 0.86 9.4 0.4 5.8 4 2 2 7 7 7 0 Domain of unknown function (DUF3447) Ank_2 PF12796.2 GAM28202.1 - 6.8e-08 32.7 0.1 0.0054 17.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28202.1 - 0.00011 22.3 0.3 18 5.7 0.0 5.6 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28202.1 - 0.00013 21.8 4.0 24 5.5 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.1 GAM28202.1 - 0.0014 19.0 1.9 0.24 11.9 0.1 3.8 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Voldacs PF03517.8 GAM28202.1 - 0.028 14.2 2.0 1.3 8.8 0.2 2.4 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling DUF4611 PF15387.1 GAM28202.1 - 8.6 6.5 8.8 17 5.6 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Ank_3 PF13606.1 GAM28203.1 - 1.8e-05 24.4 0.5 0.11 12.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.2 GAM28203.1 - 4.8e-05 23.6 0.3 0.0015 18.8 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28203.1 - 0.01 16.3 0.1 0.8 10.3 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) GoLoco PF02188.12 GAM28203.1 - 0.05 12.9 1.5 0.14 11.5 0.4 2.3 2 1 0 2 2 2 0 GoLoco motif Ank_5 PF13857.1 GAM28203.1 - 0.068 13.4 0.0 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 GAM28203.1 - 0.29 11.0 1.3 25 4.9 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.2 GAM28205.1 - 8.6e-18 64.4 14.0 0.014 15.7 0.2 9.5 6 5 0 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28205.1 - 0.00012 21.9 15.0 11 6.6 0.0 9.2 12 0 0 12 12 12 2 Ankyrin repeat TGS PF02824.16 GAM28205.1 - 0.018 14.8 0.5 0.055 13.3 0.1 2.1 2 0 0 2 2 2 0 TGS domain Ank PF00023.25 GAM28205.1 - 0.058 13.2 17.9 38 4.3 0.0 9.7 13 0 0 13 13 13 0 Ankyrin repeat Ank_2 PF12796.2 GAM28206.1 - 0.001 19.3 0.0 0.047 14.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28206.1 - 0.0061 17.0 0.2 7.3 7.2 0.0 3.6 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM28206.1 - 0.056 13.2 0.1 18 5.3 0.0 4.0 4 1 0 4 4 4 0 Ankyrin repeat DUF3447 PF11929.3 GAM28206.1 - 1.6 8.5 5.0 5.4 6.8 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Ank_3 PF13606.1 GAM28207.1 - 0.0014 18.7 0.6 0.33 11.3 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.2 GAM28207.1 - 0.0054 17.0 0.1 0.19 12.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Cut8_N PF14482.1 GAM28207.1 - 0.01 15.7 4.2 0.024 14.6 2.9 1.6 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Ank_5 PF13857.1 GAM28207.1 - 0.082 13.1 0.2 11 6.3 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeats (many copies) BTB PF00651.26 GAM28207.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Ank_2 PF12796.2 GAM28208.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.2 GAM28209.1 - 0.06 13.6 0.9 0.33 11.3 0.6 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) SpvD PF05563.7 GAM28209.1 - 0.084 12.3 1.4 0.2 11.1 0.1 1.9 1 1 1 2 2 2 0 Salmonella plasmid virulence protein SpvD PH PF00169.24 GAM28210.1 - 5.7e-10 39.3 0.1 1.4e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF758 PF05527.6 GAM28210.1 - 7.7e-06 25.6 0.7 1.2e-05 25.0 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH_9 PF15410.1 GAM28210.1 - 0.0017 18.5 0.8 0.073 13.2 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Histone PF00125.19 GAM28211.1 - 2.5e-07 30.6 1.3 0.0013 18.8 0.3 2.3 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 TAF PF02969.12 GAM28211.1 - 0.0056 16.6 0.1 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF746 PF05344.6 GAM28211.1 - 0.055 13.0 0.1 0.22 11.0 0.1 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) SNN_cytoplasm PF09051.5 GAM28211.1 - 0.18 11.5 1.7 0.6 9.8 0.2 2.1 2 0 0 2 2 2 0 Stannin cytoplasmic Peptidase_M24 PF00557.19 GAM28212.1 - 1.5e-38 132.4 0.2 2.4e-38 131.8 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 GAM28212.1 - 1e-20 74.5 0.1 1.4e-18 67.6 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain CBS PF00571.23 GAM28212.1 - 0.06 13.1 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 CBS domain LigB PF02900.13 GAM28213.1 - 3.2e-45 154.2 0.1 3.8e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Spc97_Spc98 PF04130.8 GAM28214.1 - 4.9e-122 407.9 24.7 4.9e-122 407.9 17.1 2.6 3 0 0 3 3 3 1 Spc97 / Spc98 family Kelch_4 PF13418.1 GAM28215.1 - 3.8e-08 32.9 7.0 0.00013 21.6 0.0 4.5 5 1 2 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.1 GAM28215.1 - 9e-08 31.9 5.6 0.036 14.2 0.0 4.4 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.1 GAM28215.1 - 3.5e-06 27.0 0.4 0.021 15.0 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM28215.1 - 1.8e-05 24.3 1.4 0.11 12.3 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 GAM28215.1 - 0.00012 21.5 1.5 0.33 10.5 0.1 2.8 2 0 0 2 2 2 2 Kelch motif DnaI_N PF07319.6 GAM28215.1 - 0.019 15.1 4.7 0.04 14.1 0.7 2.9 1 1 2 3 3 3 0 Primosomal protein DnaI N-terminus Kelch_5 PF13854.1 GAM28215.1 - 0.054 13.4 10.0 0.46 10.5 0.2 3.6 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.1 GAM28216.1 - 6.2e-11 41.9 6.0 5.8e-05 23.0 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 GAM28216.1 - 9e-10 38.1 1.9 2.1e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM28216.1 - 1.6e-07 31.2 0.1 0.00085 19.4 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM28216.1 - 0.00026 20.6 0.1 0.28 10.9 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 GAM28216.1 - 0.00073 19.4 6.3 0.41 10.6 0.2 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 GAM28216.1 - 0.0017 17.8 14.9 0.0026 17.2 0.1 4.1 5 0 0 5 5 5 2 Kelch motif AF0941-like PF14591.1 GAM28216.1 - 0.01 15.8 4.4 0.026 14.5 1.4 2.2 2 0 0 2 2 2 0 AF0941-like Baculo_PEP_C PF04513.7 GAM28216.1 - 0.024 14.4 0.2 0.078 12.8 0.1 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 GAM28216.1 - 0.033 13.7 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 IncA protein ALS_ss_C PF10369.4 GAM28216.1 - 0.045 13.4 0.1 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 Small subunit of acetolactate synthase DUF1664 PF07889.7 GAM28216.1 - 0.11 12.3 2.5 0.35 10.6 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Globin PF00042.17 GAM28216.1 - 0.11 12.8 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 1 0 Globin Syntaxin-6_N PF09177.6 GAM28216.1 - 0.18 12.2 1.2 0.51 10.7 0.3 2.2 2 1 0 2 2 1 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 GAM28216.1 - 0.25 11.2 1.7 4.1 7.3 0.4 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 GAM28216.1 - 0.74 9.7 3.3 1.3 8.9 1.1 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Carbpep_Y_N PF05388.6 GAM28217.1 - 0.089 12.9 0.4 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide eIF_4G1 PF12152.3 GAM28217.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Apolipoprotein PF01442.13 GAM28218.1 - 0.00082 18.9 2.1 0.00091 18.7 1.0 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain PhaP_Bmeg PF09602.5 GAM28218.1 - 0.0055 16.5 2.5 0.0081 16.0 1.7 1.2 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF883 PF05957.8 GAM28218.1 - 0.018 15.4 7.3 0.07 13.5 3.1 2.7 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF1664 PF07889.7 GAM28218.1 - 0.043 13.6 4.7 0.098 12.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 GAM28218.1 - 0.067 13.0 0.9 2.4 8.0 0.1 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HisKA_3 PF07730.8 GAM28218.1 - 0.087 13.1 0.8 2 8.8 0.4 2.4 1 1 1 2 2 2 0 Histidine kinase Spore_III_AB PF09548.5 GAM28218.1 - 0.1 12.3 2.0 0.34 10.6 0.6 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PRKCSH-like PF12999.2 GAM28218.1 - 1.5 8.3 6.8 0.82 9.2 2.2 2.1 1 1 1 2 2 2 0 Glucosidase II beta subunit-like BURP PF03181.10 GAM28218.1 - 4.6 6.3 8.3 0.88 8.6 0.2 2.1 1 1 0 2 2 2 0 BURP domain DSS1_SEM1 PF05160.8 GAM28219.1 - 4e-14 52.1 24.2 5.5e-14 51.6 16.8 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family FYDLN_acid PF09538.5 GAM28219.1 - 3.1 8.4 14.5 3.9 8.1 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) WD40 PF00400.27 GAM28220.1 - 7.9e-62 203.0 18.3 1.5e-11 43.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 GAM28220.1 - 1.6e-13 49.6 3.9 1.6e-13 49.6 2.7 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF137 PF02006.11 GAM28220.1 - 0.02 14.2 0.0 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF137 SUI1 PF01253.17 GAM28221.1 - 2.1e-10 40.2 0.9 2.1e-10 40.2 0.7 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 SDA1 PF05285.7 GAM28221.1 - 3.3e-05 23.3 17.4 6.1e-05 22.4 12.1 1.4 1 0 0 1 1 1 1 SDA1 PUA PF01472.15 GAM28221.1 - 0.0072 16.0 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 PUA domain Nop53 PF07767.6 GAM28221.1 - 0.08 11.9 17.0 0.16 10.9 11.8 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 GAM28221.1 - 0.25 9.3 24.4 0.44 8.5 16.9 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 GAM28221.1 - 0.36 10.0 19.4 0.7 9.0 13.4 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRN3 PF05327.6 GAM28221.1 - 0.62 8.1 14.6 1.1 7.3 10.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2201_N PF13203.1 GAM28221.1 - 0.82 8.7 8.5 1.8 7.7 5.9 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Dicty_REP PF05086.7 GAM28221.1 - 1 6.9 18.7 2 6.0 13.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.7 GAM28221.1 - 3.3 7.3 32.3 0.41 10.3 19.6 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 GAM28221.1 - 3.5 5.4 38.3 6.1 4.6 26.6 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 GAM28221.1 - 4.2 5.7 31.5 7.2 4.9 21.9 1.3 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 GAM28221.1 - 5.6 5.5 40.5 10 4.7 28.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SUZ PF12752.2 GAM28222.1 - 1.5e-13 51.0 0.2 5.6e-13 49.2 0.2 2.0 1 0 0 1 1 1 1 SUZ domain Pkinase_Tyr PF07714.12 GAM28224.1 - 3.8e-12 45.8 0.0 6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM28224.1 - 5.1e-12 45.5 0.1 8.8e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 GAM28225.1 - 1.2e-25 90.1 0.0 1.4e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28225.1 - 2.5e-13 49.7 0.0 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Complex1_LYR PF05347.10 GAM28226.1 - 1.4e-11 43.9 0.3 1.8e-11 43.6 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 GAM28226.1 - 7.7e-11 42.0 0.5 9.1e-11 41.8 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like L71 PF02448.10 GAM28226.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 L71 family Dynamin_M PF01031.15 GAM28227.1 - 8.6e-36 123.2 1.6 3.6e-35 121.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 GAM28227.1 - 4.6e-19 68.0 4.2 4.6e-19 68.0 2.9 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain DUF2076 PF09849.4 GAM28227.1 - 0.016 15.2 5.9 0.023 14.7 4.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sororin PF09666.5 GAM28227.1 - 0.61 10.2 9.3 0.54 10.4 0.4 2.2 1 1 1 2 2 2 0 Sororin protein Bromodomain PF00439.20 GAM28228.1 - 3.1e-05 23.7 0.0 0.0001 22.1 0.0 1.9 1 0 0 1 1 1 1 Bromodomain FHA PF00498.21 GAM28228.1 - 0.00024 21.1 0.1 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 1 FHA domain DUF1840 PF08895.6 GAM28228.1 - 0.053 13.5 0.4 0.053 13.5 0.3 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1840) Peptidase_M17 PF00883.16 GAM28229.1 - 7e-112 373.3 0.0 8.9e-112 372.9 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 GAM28229.1 - 7.7e-19 67.6 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain DUF2016 PF09436.5 GAM28229.1 - 0.084 12.4 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) AdoMet_MTase PF07757.8 GAM28230.1 - 1.1e-18 67.3 0.0 2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 GAM28230.1 - 0.00047 19.9 0.1 0.0033 17.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 GAM28230.1 - 0.0063 16.2 0.0 0.022 14.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Mucin PF01456.12 GAM28230.1 - 0.0071 16.1 23.5 0.014 15.1 8.1 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein Methyltransf_31 PF13847.1 GAM28230.1 - 0.02 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 GAM28230.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 GAM28230.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Dicty_REP PF05086.7 GAM28230.1 - 5.2 4.7 13.1 3.7 5.1 2.6 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Acyl-CoA_dh_1 PF00441.19 GAM28231.1 - 1.1e-26 93.7 0.0 4e-26 91.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 GAM28231.1 - 7.5e-11 42.4 0.0 4.8e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 GAM28231.1 - 2e-06 27.2 0.2 3.5e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Lipocalin PF00061.18 GAM28232.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family Ank_2 PF12796.2 GAM28233.1 - 1.6e-40 137.3 30.7 2.7e-09 37.2 0.9 5.7 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28233.1 - 4.3e-33 113.1 14.2 0.00013 22.4 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28233.1 - 6.5e-33 112.0 24.8 0.00031 20.8 0.1 12.8 2 1 11 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28233.1 - 4.2e-25 85.3 19.8 0.14 12.4 0.0 12.7 6 3 7 13 13 13 6 Ankyrin repeat Ank PF00023.25 GAM28233.1 - 2.3e-19 68.1 20.5 0.34 10.8 0.1 12.4 13 0 0 13 13 13 7 Ankyrin repeat Rbsn PF11464.3 GAM28233.1 - 0.0024 17.4 1.8 78 2.9 0.0 6.7 8 0 0 8 8 8 0 Rabenosyn Rab binding domain PepX_N PF09168.5 GAM28233.1 - 0.0035 17.6 0.5 54 3.9 0.0 5.1 3 2 4 8 8 8 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal RNase_P_p30 PF01876.11 GAM28233.1 - 0.056 12.6 0.8 68 2.6 0.0 4.7 3 3 4 7 7 7 0 RNase P subunit p30 FAD_binding_9 PF08021.6 GAM28233.1 - 0.079 12.9 2.7 1.5 8.7 0.0 3.7 4 0 0 4 4 4 0 Siderophore-interacting FAD-binding domain DUF1707 PF08044.6 GAM28233.1 - 0.17 11.6 4.7 28 4.5 0.0 5.1 7 0 0 7 7 7 0 Domain of unknown function (DUF1707) zf-CCHC_6 PF15288.1 GAM28234.1 - 0.00015 21.3 0.3 0.0003 20.4 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 GAM28234.1 - 0.0015 18.3 1.1 0.0015 18.3 0.8 1.7 2 0 0 2 2 2 1 Zinc knuckle MIP-T3 PF10243.4 GAM28234.1 - 0.089 11.2 17.5 0.085 11.3 12.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 GAM28234.1 - 0.58 9.8 72.4 15 5.2 50.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1510 PF07423.6 GAM28234.1 - 4.5 6.5 8.0 5.7 6.2 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDRGK PF09756.4 GAM28235.1 - 1.1 8.6 18.1 1.1 8.6 12.6 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3439 PF11921.3 GAM28235.1 - 1.1 9.0 10.1 1.1 9.0 6.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) CDC45 PF02724.9 GAM28235.1 - 3.4 5.5 11.5 3.5 5.5 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.3 GAM28235.1 - 4.2 7.0 10.7 4.7 6.8 7.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Tho2 PF11262.3 GAM28235.1 - 4.4 6.2 10.0 4.7 6.1 7.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NARP1 PF12569.3 GAM28235.1 - 4.9 5.7 14.4 5 5.7 10.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sporozoite_P67 PF05642.6 GAM28235.1 - 5.2 4.7 10.7 5.7 4.6 7.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NST1 PF13945.1 GAM28235.1 - 5.6 6.9 19.0 69 3.4 13.1 1.9 1 1 0 1 1 1 0 Salt tolerance down-regulator Mating_C PF12737.2 GAM28235.1 - 8.7 5.1 16.4 0.78 8.5 5.5 2.0 1 1 1 2 2 2 0 C-terminal domain of homeodomain 1 Proteasome PF00227.21 GAM28236.1 - 1.7e-64 216.6 0.1 2.1e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 GAM28236.1 - 9.3e-14 50.4 0.4 1.7e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GatB_N PF02934.10 GAM28238.1 - 3.7e-104 347.6 0.0 5.1e-104 347.1 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 GAM28238.1 - 5.2e-42 143.0 0.2 9.3e-42 142.2 0.1 1.4 1 0 0 1 1 1 1 GatB domain SpoVIF PF14069.1 GAM28238.1 - 0.0037 16.9 0.4 1 9.1 0.0 3.1 2 1 1 3 3 3 2 Stage VI sporulation protein F 60KD_IMP PF02096.15 GAM28239.1 - 3.4e-37 128.0 8.6 3.4e-37 128.0 6.0 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein TIG PF01833.19 GAM28240.1 - 1.2e-13 50.8 18.0 5.3e-08 32.7 0.6 4.6 4 0 0 4 4 4 3 IPT/TIG domain EGF_2 PF07974.8 GAM28240.1 - 0.007 16.5 13.1 0.02 15.0 9.1 1.8 1 0 0 1 1 1 1 EGF-like domain LRR_8 PF13855.1 GAM28240.1 - 0.0099 15.6 7.9 0.014 15.1 0.6 3.5 2 1 1 3 3 3 1 Leucine rich repeat Laminin_EGF PF00053.19 GAM28240.1 - 0.58 10.1 7.9 1.6 8.7 5.5 1.7 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) TIG PF01833.19 GAM28241.1 - 3.1e-18 65.5 26.8 1.7e-07 31.0 2.0 4.7 5 0 0 5 5 5 3 IPT/TIG domain SKG6 PF08693.5 GAM28241.1 - 0.015 14.5 0.5 0.015 14.5 0.3 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pkinase PF00069.20 GAM28242.1 - 6.4e-73 245.1 0.0 9e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28242.1 - 8.2e-55 185.6 0.0 1.7e-54 184.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM28242.1 - 0.0019 17.2 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM28242.1 - 0.0045 16.7 0.0 1.6 8.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family CASP_C PF08172.7 GAM28242.1 - 0.0073 15.3 0.3 0.018 14.1 0.2 1.6 1 0 0 1 1 1 1 CASP C terminal YrbL-PhoP_reg PF10707.4 GAM28242.1 - 0.0079 15.5 1.1 0.011 15.0 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 GAM28242.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Syntaxin PF00804.20 GAM28242.1 - 0.19 11.8 4.5 0.05 13.7 0.7 1.8 2 0 0 2 2 2 0 Syntaxin Peptidase_M41 PF01434.13 GAM28243.1 - 2.1e-72 243.0 0.3 3.5e-72 242.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 GAM28243.1 - 2.8e-44 150.5 0.0 7.2e-44 149.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM28243.1 - 0.00027 20.6 0.3 0.0013 18.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 GAM28243.1 - 0.00037 21.3 0.0 0.0016 19.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 GAM28243.1 - 0.0011 19.0 0.5 0.051 13.7 0.1 3.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM28243.1 - 0.0046 16.0 0.0 0.013 14.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM28243.1 - 0.0092 15.7 0.7 0.026 14.2 0.5 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 GAM28243.1 - 0.012 15.6 0.1 0.095 12.6 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_2 PF07724.9 GAM28243.1 - 0.012 15.4 0.3 0.07 13.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 GAM28243.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 GAM28243.1 - 0.027 13.8 0.5 0.1 11.9 0.2 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 GAM28243.1 - 0.047 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAM28243.1 - 0.057 12.5 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 GAM28243.1 - 0.34 10.7 3.3 0.28 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF3595 PF12166.3 GAM28246.1 - 0.027 13.3 0.2 0.031 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) zf-CCHC PF00098.18 GAM28247.1 - 9.5e-07 28.4 5.3 1.6e-06 27.7 3.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 GAM28247.1 - 0.014 14.8 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 GAM28247.1 - 0.12 12.0 1.6 0.22 11.2 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_5 PF13893.1 GAM28247.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 GAM28247.1 - 0.54 8.6 23.2 0.63 8.4 16.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PP2C PF00481.16 GAM28249.1 - 4.5e-65 219.5 0.0 4.5e-65 219.5 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Atrophin-1 PF03154.10 GAM28249.1 - 0.021 13.0 6.4 0.027 12.6 4.4 1.0 1 0 0 1 1 1 0 Atrophin-1 family RAP1 PF07218.6 GAM28249.1 - 9.6 4.1 8.3 12 3.8 5.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EI24 PF07264.6 GAM28250.1 - 3.4e-29 101.8 25.4 5.3e-29 101.2 17.6 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF996 PF06195.8 GAM28250.1 - 0.013 15.4 1.5 0.013 15.4 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF996) RRM_5 PF13893.1 GAM28251.1 - 2.2e-42 142.7 2.2 2e-11 43.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28251.1 - 3.5e-40 135.8 0.1 8.8e-12 44.8 0.0 5.2 4 1 1 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM28251.1 - 1.1e-35 121.0 0.0 7.3e-09 35.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 GAM28251.1 - 1.1 7.4 28.9 2.6 6.1 20.0 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 GAM28251.1 - 3 7.6 12.7 7.9 6.2 8.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Diphthamide_syn PF01866.12 GAM28254.1 - 7.3e-112 373.5 0.0 8.9e-112 373.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pro_isomerase PF00160.16 GAM28255.1 - 1.3e-51 174.8 0.0 2.6e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 GAM28255.1 - 1.2e-05 25.1 1.8 0.00019 21.2 0.0 3.1 3 0 0 3 3 3 1 U-box domain Rtf2 PF04641.7 GAM28255.1 - 1.3e-05 24.5 0.1 1.3e-05 24.5 0.1 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger Glyco_hydro_77 PF02446.12 GAM28256.1 - 3.8e-157 523.8 4.4 5.2e-157 523.3 3.1 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.14 GAM28256.1 - 7.1e-29 99.2 5.4 3.7e-19 68.1 0.6 3.7 2 1 1 3 3 3 3 Starch binding domain DUF4219 PF13961.1 GAM28256.1 - 0.41 10.1 4.0 3.2 7.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Pneumovirus_M2 PF06436.6 GAM28257.1 - 0.12 11.5 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) FimP PF09766.4 GAM28257.1 - 0.15 11.1 0.0 0.3 10.0 0.0 1.4 2 0 0 2 2 2 0 Fms-interacting protein zf-MYND PF01753.13 GAM28258.1 - 4.6e-09 36.0 7.0 4.6e-09 36.0 4.8 4.5 2 1 2 4 4 4 1 MYND finger Glyco_hydro_18 PF00704.23 GAM28261.1 - 2.6e-16 60.0 0.4 3.4e-16 59.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Dynamin_N PF00350.18 GAM28262.1 - 2.1e-13 50.4 0.0 9.1e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28262.1 - 0.00019 21.3 0.0 0.00088 19.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 GAM28262.1 - 0.0044 15.9 0.0 0.0075 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 GAM28262.1 - 0.0047 15.6 0.0 0.007 15.0 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein DUF258 PF03193.11 GAM28262.1 - 0.0054 15.9 0.0 0.061 12.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 GAM28262.1 - 0.0058 15.6 0.1 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_29 PF13555.1 GAM28262.1 - 0.0069 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM28262.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 GAM28262.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 GAM28262.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAM28264.1 - 0.0083 15.9 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family SET PF00856.23 GAM28265.1 - 2.2e-05 24.8 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SET domain SET PF00856.23 GAM28266.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 2 1 0 2 2 2 0 SET domain TPR_17 PF13431.1 GAM28266.1 - 0.042 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 GAM28266.1 - 0.078 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 TPR repeat UbiD PF01977.11 GAM28266.1 - 0.13 10.7 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Dynamin_N PF00350.18 GAM28267.1 - 1.8e-12 47.3 0.0 6.8e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28267.1 - 0.00047 20.1 0.0 0.0025 17.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 GAM28267.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 GAM28267.1 - 0.016 14.3 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 GAM28267.1 - 0.035 13.6 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 GAM28267.1 - 0.049 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 GAM28267.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 GAM28268.1 - 0.071 12.9 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family zf-Tim10_DDP PF02953.10 GAM28268.1 - 0.13 11.5 0.4 0.26 10.5 0.3 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger nsp7 PF08716.5 GAM28270.1 - 0.045 14.1 0.1 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 nsp7 replicase Vps5 PF09325.5 GAM28271.1 - 0.1 11.8 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Pkinase_Tyr PF07714.12 GAM28272.1 - 0.026 13.6 0.3 0.078 12.0 0.1 1.9 2 1 0 2 2 2 0 Protein tyrosine kinase Dynamin_N PF00350.18 GAM28273.1 - 1.5e-13 50.9 0.0 4.7e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28273.1 - 0.00038 20.3 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 GAM28273.1 - 0.0063 15.4 0.0 0.009 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 GAM28273.1 - 0.007 15.0 0.0 0.01 14.5 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_29 PF13555.1 GAM28273.1 - 0.0091 15.5 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 GAM28273.1 - 0.0099 14.9 0.0 0.022 13.7 0.0 1.6 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 GAM28273.1 - 0.01 15.0 0.0 0.073 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM28273.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter EF-hand_2 PF09068.6 GAM28273.1 - 0.074 13.1 0.1 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 EF hand AAA_14 PF13173.1 GAM28273.1 - 0.08 12.8 0.1 0.26 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 GAM28273.1 - 0.096 12.3 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 GAM28273.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 GAM28273.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAM28275.1 - 8.4e-12 45.2 0.0 2.8e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28275.1 - 0.0037 17.2 0.0 0.026 14.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.10 GAM28275.1 - 0.0049 15.5 0.1 0.0095 14.6 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein FANCI_S2 PF14676.1 GAM28275.1 - 0.0083 16.0 1.5 0.0083 16.0 1.1 2.1 2 0 0 2 2 2 1 FANCI solenoid 2 DUF258 PF03193.11 GAM28275.1 - 0.0092 15.1 0.2 0.083 12.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM28275.1 - 0.02 15.1 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 GAM28275.1 - 0.041 13.3 1.1 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 GAM28275.1 - 0.043 12.7 0.0 0.094 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 GAM28275.1 - 0.05 13.1 0.6 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 GAM28275.1 - 0.077 12.4 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Aldo_ket_red PF00248.16 GAM28276.1 - 6.8e-53 179.3 0.0 9.6e-53 178.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 GAM28276.1 - 0.022 14.9 0.0 0.049 13.8 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AAA_16 PF13191.1 GAM28277.1 - 0.013 15.5 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 GAM28277.1 - 0.02 15.0 0.7 0.093 12.9 0.0 2.6 3 0 0 3 3 3 0 RNA helicase DAP3 PF10236.4 GAM28277.1 - 0.027 13.4 0.1 0.16 10.8 0.0 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 GAM28277.1 - 0.056 13.3 0.3 0.35 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 GAM28277.1 - 0.075 12.6 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Myosin_head PF00063.16 GAM28278.1 - 3.7e-239 795.3 2.3 7.9e-239 794.2 1.6 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 GAM28278.1 - 8.4e-46 155.7 1.3 1.9e-45 154.6 0.9 1.6 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 GAM28278.1 - 9.7e-19 66.5 0.2 2.2e-18 65.3 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 GAM28278.1 - 1.4e-17 62.9 0.1 2.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 GAM28278.1 - 1.9e-12 46.4 0.0 4.2e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 GAM28278.1 - 0.0036 17.4 0.0 0.016 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 GAM28278.1 - 0.0044 17.8 0.1 0.075 13.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 GAM28278.1 - 0.009 15.1 0.1 0.024 13.7 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 GAM28278.1 - 0.019 15.2 0.1 0.077 13.2 0.0 2.2 1 0 0 1 1 1 0 AAA domain Phage_Treg PF04761.7 GAM28278.1 - 0.052 13.3 0.2 0.37 10.5 0.1 2.6 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator DUF258 PF03193.11 GAM28278.1 - 0.074 12.2 0.2 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 GAM28278.1 - 0.077 13.1 1.8 0.23 11.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase NACHT PF05729.7 GAM28278.1 - 0.077 12.6 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 GAM28278.1 - 0.086 13.1 0.4 0.33 11.2 0.1 2.1 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 GAM28278.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 GAM28278.1 - 0.096 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 GAM28278.1 - 0.13 10.8 0.1 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 GAM28278.1 - 0.22 11.0 0.1 0.38 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 GAM28279.1 - 0.00065 19.5 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Kinesin PF00225.18 GAM28280.1 - 1e-109 366.3 6.8 1e-109 366.3 4.7 3.8 3 0 0 3 3 3 1 Kinesin motor domain DUF3450 PF11932.3 GAM28280.1 - 0.00018 20.8 11.3 0.00018 20.8 7.9 13.8 2 1 13 15 15 15 1 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.7 GAM28280.1 - 0.00025 20.7 25.6 0.00025 20.7 17.8 13.5 3 2 9 12 12 12 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 GAM28280.1 - 2.8 7.0 87.3 0.34 10.0 3.5 10.0 1 1 6 11 11 11 0 Reovirus sigma C capsid protein Dynamin_N PF00350.18 GAM28281.1 - 1.2e-11 44.7 0.0 1.1e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Adeno_IVa2 PF02456.10 GAM28281.1 - 2.2e-05 23.2 0.1 2.2e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 Adenovirus IVa2 protein Pkinase PF00069.20 GAM28281.1 - 0.0013 17.9 0.0 0.0037 16.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain T2SE PF00437.15 GAM28281.1 - 0.0045 15.9 0.0 0.0092 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF869 PF05911.6 GAM28281.1 - 0.04 12.1 0.4 0.066 11.4 0.3 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) FtsK_SpoIIIE PF01580.13 GAM28281.1 - 0.095 12.1 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 GAM28282.1 - 2.5e-08 33.9 0.0 6.9e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Pkinase PF00069.20 GAM28282.1 - 1.1e-06 28.0 0.0 2.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.18 GAM28282.1 - 0.00021 21.2 0.0 0.00086 19.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase_Tyr PF07714.12 GAM28282.1 - 0.003 16.6 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM28282.1 - 0.051 12.6 0.2 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 GAM28282.1 - 0.1 12.9 0.0 0.34 11.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 GAM28283.1 - 2.7e-14 53.3 0.0 1.1e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28283.1 - 0.0037 17.2 0.0 0.03 14.2 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 GAM28283.1 - 0.013 14.6 0.0 0.73 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 GAM28284.1 - 1.1e-10 41.6 0.0 4.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28284.1 - 0.0036 17.2 0.1 0.021 14.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pigment_DH PF06324.6 GAM28284.1 - 0.01 15.0 5.0 0.086 12.1 2.5 2.6 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) AAA_29 PF13555.1 GAM28284.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 GAM28284.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 GAM28284.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM28285.1 - 1.3e-11 44.5 0.1 1.4e-10 41.2 0.0 2.7 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 GAM28285.1 - 0.0012 18.8 0.1 0.013 15.4 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.20 GAM28286.1 - 7.2e-26 90.8 0.2 8.5e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28286.1 - 5.6e-14 51.8 0.0 9.2e-14 51.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 GAM28286.1 - 0.059 12.4 0.1 0.089 11.9 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Kdo PF06293.9 GAM28286.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynamin_N PF00350.18 GAM28287.1 - 6.7e-12 45.5 0.0 1.6e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAM28287.1 - 2.6e-05 24.1 0.0 0.00049 20.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Pkinase PF00069.20 GAM28287.1 - 0.017 14.2 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain AAA_33 PF13671.1 GAM28287.1 - 0.056 13.3 0.3 3.2 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain SlyX PF04102.7 GAM28287.1 - 0.073 13.4 0.4 0.36 11.2 0.2 2.2 2 0 0 2 2 2 0 SlyX Zeta_toxin PF06414.7 GAM28287.1 - 0.12 11.4 0.0 1.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 GAM28287.1 - 0.13 12.6 0.4 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF3320 PF11784.3 GAM28287.1 - 0.15 11.5 0.4 0.59 9.6 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) BP28CT PF08146.7 GAM28288.1 - 0.11 12.2 4.0 1.3 8.7 0.5 2.6 2 0 0 2 2 2 0 BP28CT (NUC211) domain DASH_Duo1 PF08651.5 GAM28288.1 - 0.3 10.7 3.3 2.1 8.0 0.1 3.3 2 1 1 3 3 3 0 DASH complex subunit Duo1 Dynamin_N PF00350.18 GAM28289.1 - 1.2e-10 41.4 0.0 3.6e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Pkinase PF00069.20 GAM28289.1 - 5.4e-08 32.2 0.1 6.9e-07 28.6 0.0 2.6 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28289.1 - 0.0057 15.7 0.1 0.028 13.4 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase MMR_HSR1 PF01926.18 GAM28289.1 - 0.0067 16.3 0.1 0.053 13.4 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 GAM28289.1 - 0.0077 15.1 0.1 0.018 13.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.1 GAM28289.1 - 0.0077 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 GAM28289.1 - 0.047 14.0 0.0 42 4.3 0.1 3.3 2 2 1 3 3 3 0 AAA domain Dynamin_N PF00350.18 GAM28290.1 - 9e-12 45.1 0.0 2.5e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 GAM28290.1 - 0.0026 17.7 0.2 0.032 14.2 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 GAM28290.1 - 0.042 13.3 0.2 0.093 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 GAM28290.1 - 0.051 13.0 0.0 0.18 11.2 0.0 1.8 2 1 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 GAM28290.1 - 0.058 12.5 0.3 0.21 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 GAM28290.1 - 0.072 13.3 0.1 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 GAM28291.1 - 1.2e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Pkinase PF00069.20 GAM28291.1 - 0.0043 16.2 0.0 0.0084 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.22 GAM28291.1 - 0.0045 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 GAM28291.1 - 0.022 14.7 0.1 0.18 11.8 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 GAM28291.1 - 0.026 13.9 1.2 0.067 12.6 0.9 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 GAM28291.1 - 0.069 12.3 0.0 0.19 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HSBP1 PF06825.7 GAM28291.1 - 0.5 9.9 3.4 8.7 6.0 1.0 2.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Pkinase PF00069.20 GAM28292.1 - 3.5e-35 121.4 0.0 6.4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28292.1 - 9.6e-25 87.1 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamin_N PF00350.18 GAM28292.1 - 3.8e-14 52.8 0.0 1.2e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 GAM28292.1 - 0.0019 18.9 0.0 0.023 15.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 GAM28292.1 - 0.0055 16.6 0.0 0.034 14.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase HD_4 PF13328.1 GAM28292.1 - 0.017 14.8 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 HD domain EcKinase PF02958.15 GAM28292.1 - 0.017 14.2 0.2 0.069 12.2 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase Kdo PF06293.9 GAM28292.1 - 0.026 13.6 0.1 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.22 GAM28292.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 GAM28292.1 - 0.047 13.9 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Peptidase_C48 PF02902.14 GAM28295.1 - 0.00011 21.9 0.2 0.00019 21.1 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Dicty_REP PF05086.7 GAM28295.1 - 0.0029 15.4 5.0 0.0032 15.3 3.5 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Sporozoite_P67 PF05642.6 GAM28295.1 - 0.0084 14.0 5.3 0.01 13.7 3.6 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SSP160 PF06933.6 GAM28295.1 - 0.041 11.8 15.8 0.049 11.6 11.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4207 PF13904.1 GAM28295.1 - 0.55 9.5 4.8 0.79 9.0 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Paramyxo_C PF01692.13 GAM28295.1 - 2.3 7.7 5.1 3.6 7.1 3.6 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c adh_short PF00106.20 GAM28297.1 - 1.6e-24 86.6 0.0 3.8e-24 85.4 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM28297.1 - 5.3e-17 62.4 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM28297.1 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM28297.1 - 0.00027 20.6 0.1 0.00067 19.3 0.1 1.6 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 GAM28297.1 - 0.0057 16.6 0.1 0.011 15.6 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 GAM28297.1 - 0.029 13.7 0.1 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box PF00646.28 GAM28298.1 - 3.4e-05 23.3 0.2 7.4e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 GAM28298.1 - 7.6e-05 22.3 0.6 0.0003 20.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like FAM101 PF15068.1 GAM28298.1 - 0.064 12.6 3.3 0.11 11.9 2.3 1.4 1 0 0 1 1 1 0 FAM101 family DUF3328 PF11807.3 GAM28298.1 - 0.15 11.7 2.5 0.2 11.3 1.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) MSA-2c PF12238.3 GAM28298.1 - 0.16 11.6 2.1 0.25 10.9 1.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase PF00069.20 GAM28300.1 - 7e-78 261.3 0.2 8.4e-78 261.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28300.1 - 1.8e-35 122.2 0.2 2.2e-35 121.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM28300.1 - 4e-07 29.2 0.0 3.6e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 GAM28300.1 - 0.00043 19.4 0.1 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM28300.1 - 0.00061 19.5 0.0 0.3 10.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 GAM28300.1 - 0.011 15.1 0.6 0.02 14.2 0.4 1.4 1 0 0 1 1 1 0 RIO1 family Solute_trans_a PF03619.11 GAM28301.1 - 6e-97 324.2 24.0 8e-97 323.8 16.7 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Picorna_P3A PF06363.6 GAM28301.1 - 0.68 9.9 2.8 7.9 6.5 0.3 2.7 2 0 0 2 2 2 0 Picornaviridae P3A protein PIP5K PF01504.13 GAM28302.1 - 6.2e-71 238.4 0.9 1e-70 237.7 0.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ank_2 PF12796.2 GAM28302.1 - 6.4e-32 109.7 0.0 1.3e-14 54.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28302.1 - 7.8e-31 104.3 0.0 1.6e-06 27.6 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 GAM28302.1 - 2.4e-29 101.1 0.1 5.9e-13 48.9 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28302.1 - 1.3e-21 76.0 0.4 3.5e-08 33.4 0.0 4.5 3 2 2 5 5 4 4 Ankyrin repeats (many copies) EF-hand_7 PF13499.1 GAM28302.1 - 2.1e-18 66.1 9.1 3.9e-10 39.7 0.6 3.9 3 1 3 6 6 6 4 EF-hand domain pair Ank_3 PF13606.1 GAM28302.1 - 5.7e-17 60.1 0.0 0.00039 20.4 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat EF-hand_6 PF13405.1 GAM28302.1 - 1.2e-13 49.7 0.6 0.00022 20.8 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 GAM28302.1 - 3.6e-12 44.6 0.3 0.0019 17.3 0.2 3.7 3 0 0 3 3 3 3 EF hand C1_1 PF00130.17 GAM28302.1 - 2.7e-11 43.0 6.8 5.4e-11 42.0 4.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) NADPH_Ox PF08414.5 GAM28302.1 - 1.2e-07 31.7 0.1 2.2e-06 27.6 0.1 2.7 2 1 1 3 3 3 1 Respiratory burst NADPH oxidase EF-hand_8 PF13833.1 GAM28302.1 - 1.5e-05 24.5 0.3 0.026 14.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 GAM28302.1 - 0.0018 18.3 1.6 0.05 13.6 0.6 2.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 GAM28302.1 - 0.0069 15.6 0.2 0.069 12.5 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.1 GAM28302.1 - 0.11 12.4 0.1 2.8 7.9 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Hamartin PF04388.7 GAM28302.1 - 0.67 8.5 12.1 1.2 7.7 8.4 1.3 1 0 0 1 1 1 0 Hamartin protein Pur_DNA_glyco PF02245.11 GAM28303.1 - 0.087 11.9 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) Vault PF01505.13 GAM28304.1 - 2.9e-60 200.0 0.5 6.6e-14 51.6 0.0 5.7 5 0 0 5 5 5 5 Major Vault Protein repeat MVP_shoulder PF11978.3 GAM28304.1 - 3.8e-48 162.2 0.0 7.2e-48 161.3 0.0 1.5 1 0 0 1 1 1 1 Shoulder domain Urb2 PF10441.4 GAM28305.1 - 3.4e-06 26.8 6.9 3.4e-06 26.8 4.8 7.2 5 2 0 5 5 5 1 Urb2/Npa2 family FNIP PF05725.7 GAM28306.1 - 1.1e-45 153.3 11.7 7e-13 48.2 0.1 7.9 7 2 3 10 10 10 6 FNIP Repeat FNIP PF05725.7 GAM28307.1 - 5e-65 215.2 0.0 1.1e-12 47.7 0.1 9.2 6 2 1 9 9 9 8 FNIP Repeat TFIIA PF03153.8 GAM28307.1 - 0.013 15.4 8.2 0.016 15.0 5.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.7 GAM28308.1 - 8.9e-48 159.9 22.2 3.7e-14 52.3 0.4 7.0 5 1 2 7 7 7 6 FNIP Repeat FNIP PF05725.7 GAM28310.1 - 2.5e-51 171.3 27.0 1e-16 60.6 0.3 5.8 4 1 3 7 7 7 5 FNIP Repeat LRR_4 PF12799.2 GAM28310.1 - 0.46 10.1 3.7 0.84 9.3 0.2 3.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Ribosomal_L18ae PF01775.12 GAM28311.1 - 1.9e-52 176.3 3.6 2.6e-52 175.9 2.5 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CD36 PF01130.16 GAM28311.1 - 0.029 12.6 0.1 0.031 12.5 0.0 1.1 1 0 0 1 1 1 0 CD36 family His_Phos_2 PF00328.17 GAM28312.1 - 3.7e-20 72.5 0.0 5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RhoGEF PF00621.15 GAM28313.1 - 1.5e-47 161.8 0.2 4.5e-47 160.2 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM28313.1 - 0.00026 21.1 0.0 0.0009 19.4 0.0 2.0 1 0 0 1 1 1 1 PH domain DUF2721 PF11026.3 GAM28313.1 - 0.0022 17.6 7.1 0.057 13.0 0.6 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2721) LMSTEN PF07988.7 GAM28314.1 - 0.049 12.9 0.1 0.084 12.1 0.1 1.3 1 0 0 1 1 1 0 LMSTEN motif PH PF00169.24 GAM28315.1 - 9.8e-18 64.2 1.1 2.3e-17 63.1 0.8 1.7 1 0 0 1 1 1 1 PH domain TPR_12 PF13424.1 GAM28315.1 - 1.1e-08 34.8 6.5 0.0015 18.4 0.1 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat PH_11 PF15413.1 GAM28315.1 - 1.5e-07 31.6 2.6 1.8e-07 31.4 0.3 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 GAM28315.1 - 0.0086 15.9 0.4 0.022 14.6 0.3 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_8 PF13181.1 GAM28315.1 - 0.026 14.2 4.8 14 5.7 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PH_8 PF15409.1 GAM28315.1 - 0.042 13.9 0.3 0.16 12.0 0.2 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 GAM28315.1 - 0.056 13.5 5.0 0.14 12.3 0.8 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Peptidase_M10_C PF08548.6 GAM28315.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal TPR_11 PF13414.1 GAM28315.1 - 0.13 11.9 2.2 3.1 7.5 0.0 3.5 3 1 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 GAM28315.1 - 0.38 10.7 3.2 2.2 8.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM28315.1 - 0.42 10.5 3.6 39 4.3 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 GAM28316.1 - 1.7e-34 118.8 0.0 2e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Gtr1_RagA PF04670.7 GAM28318.1 - 1.7e-103 344.7 2.6 2.3e-103 344.3 1.8 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 GAM28318.1 - 8.2e-10 38.3 0.0 1.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM28318.1 - 2.9e-09 36.3 0.1 4.9e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM28318.1 - 3.6e-07 30.1 0.0 9.1e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM28318.1 - 9e-06 26.1 1.2 1.8e-05 25.2 0.1 2.1 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 GAM28318.1 - 0.00081 18.6 0.1 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAM28318.1 - 0.02 14.3 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ClpS PF02617.12 GAM28318.1 - 0.074 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS TMPIT PF07851.8 GAM28319.1 - 8.4e-99 330.7 7.4 9.9e-99 330.5 5.1 1.0 1 0 0 1 1 1 1 TMPIT-like protein DNA_Packaging PF11053.3 GAM28319.1 - 0.07 12.7 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Terminase DNA packaging enzyme CENP-H PF05837.7 GAM28319.1 - 2.5 8.3 6.8 7.6 6.7 0.4 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Lyase_aromatic PF00221.14 GAM28320.1 - 9.4e-183 607.9 0.6 1.1e-182 607.7 0.4 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase FNIP PF05725.7 GAM28321.1 - 1.4e-32 111.3 3.4 2.5e-12 46.5 0.1 3.6 1 1 1 3 3 3 3 FNIP Repeat FNIP PF05725.7 GAM28322.1 - 4.8e-62 205.6 9.9 6.7e-14 51.5 0.1 8.1 5 2 4 9 9 9 7 FNIP Repeat Crystallin PF00525.13 GAM28322.1 - 0.001 19.2 3.9 0.0053 16.9 0.2 2.9 2 1 1 3 3 3 2 Alpha crystallin A chain, N terminal DUF2804 PF10974.3 GAM28322.1 - 0.17 10.7 0.2 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) FNIP PF05725.7 GAM28323.1 - 2.1e-66 219.6 40.4 4.5e-12 45.7 0.0 9.3 3 3 8 12 12 12 11 FNIP Repeat FNIP PF05725.7 GAM28324.1 - 1.3e-63 210.7 40.7 7.9e-15 54.5 0.5 10.2 6 3 2 10 10 10 8 FNIP Repeat LRR_1 PF00560.28 GAM28324.1 - 7.2 7.0 9.0 49 4.5 0.0 5.6 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 GAM28324.1 - 10 5.8 16.6 1.4 8.6 1.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 GAM28325.1 - 1.3e-72 239.5 45.9 3.5e-14 52.4 0.2 7.9 2 1 8 10 10 10 10 FNIP Repeat LRR_4 PF12799.2 GAM28325.1 - 6 6.5 10.1 2.9 7.6 1.1 4.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 GAM28326.1 - 1.3e-61 204.3 28.3 2.9e-13 49.5 0.3 8.5 4 2 5 9 9 9 8 FNIP Repeat Atg14 PF10186.4 GAM28327.1 - 4.9e-17 61.8 6.8 4.9e-17 61.8 4.7 2.4 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 C2 PF00168.25 GAM28327.1 - 0.046 13.5 0.2 0.046 13.5 0.1 2.6 2 0 0 2 2 2 0 C2 domain Cyclin PF08613.6 GAM28328.1 - 0.00091 19.6 0.2 0.00091 19.6 0.1 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM28328.1 - 0.0015 18.1 0.2 0.0023 17.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ATP-synt PF00231.14 GAM28328.1 - 0.057 12.7 0.1 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 ATP synthase WD40 PF00400.27 GAM28329.1 - 4.6e-31 105.5 11.8 1.6e-08 34.1 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM28329.1 - 0.00033 20.4 0.0 0.0068 16.1 0.0 3.1 2 2 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DZR PF12773.2 GAM28329.1 - 0.86 9.4 10.5 2 8.2 7.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF3430 PF11912.3 GAM28330.1 - 1.4e-20 74.0 14.2 1.7e-20 73.8 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3430 PF11912.3 GAM28331.1 - 4.1e-18 65.9 30.4 4.1e-18 65.9 21.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) tRNA_anti_2 PF13742.1 GAM28331.1 - 0.059 13.2 0.2 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain TPPK_C PF12555.3 GAM28331.1 - 0.22 11.2 1.4 0.39 10.4 1.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal FNIP PF05725.7 GAM28332.1 - 2.8e-51 171.1 36.6 6.8e-13 48.3 2.0 8.5 6 2 1 8 8 8 7 FNIP Repeat FNIP PF05725.7 GAM28333.1 - 9.1e-76 249.6 39.2 1.7e-13 50.2 0.4 9.5 9 1 1 10 10 10 9 FNIP Repeat Ribosomal_L24e PF01246.15 GAM28334.1 - 3e-29 100.6 3.9 3e-29 100.6 2.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2175 PF09943.4 GAM28334.1 - 5 7.2 7.5 3.5 7.7 0.5 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) UCH PF00443.24 GAM28335.1 - 1.5e-53 181.6 0.1 1.5e-53 181.6 0.1 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM28335.1 - 2.9e-28 99.1 3.4 1.2e-27 97.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pkinase_Tyr PF07714.12 GAM28336.1 - 2.1e-60 203.9 0.0 2.7e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM28336.1 - 1.7e-48 165.0 0.0 2.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM28336.1 - 7.1e-16 57.7 0.1 1.3e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 GAM28336.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 GAM28336.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family WD40 PF00400.27 GAM28338.1 - 3.1e-23 80.7 8.7 1.2e-06 28.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_S29 PF02907.10 GAM28338.1 - 0.00046 19.7 0.1 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_M15_4 PF13539.1 GAM28338.1 - 0.092 13.1 1.1 1.7 9.1 0.3 2.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase SIR2 PF02146.12 GAM28339.1 - 1.2e-26 93.5 0.0 2.1e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TusA PF01206.12 GAM28339.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA SIR2 PF02146.12 GAM28340.1 - 5.4e-16 58.8 0.0 6.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family ARS2 PF04959.8 GAM28343.1 - 0.094 12.8 0.3 0.12 12.5 0.2 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 CagY_I PF14585.1 GAM28343.1 - 0.099 12.5 0.5 0.15 12.0 0.4 1.3 1 0 0 1 1 1 0 CagY type 1 repeat Myosin_head PF00063.16 GAM28344.1 - 1e-232 774.0 11.6 1e-232 774.0 8.1 2.9 2 1 0 2 2 1 1 Myosin head (motor domain) MyTH4 PF00784.12 GAM28344.1 - 1.4e-50 170.0 5.0 1.4e-24 86.2 0.1 3.2 3 0 0 3 3 3 2 MyTH4 domain SH3_2 PF07653.12 GAM28344.1 - 4.4e-11 42.1 0.0 8.2e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAM28344.1 - 5.7e-11 41.8 0.0 1.2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM28344.1 - 4.4e-09 35.5 0.0 1.1e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 SH3 domain RA PF00788.18 GAM28344.1 - 3.4e-08 33.8 0.0 4e-05 24.0 0.0 3.5 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain IQ PF00612.22 GAM28344.1 - 4e-07 29.0 25.3 0.0026 17.2 0.3 5.0 5 0 0 5 5 4 3 IQ calmodulin-binding motif FERM_M PF00373.13 GAM28344.1 - 5.8e-05 23.2 6.6 0.00037 20.6 0.1 3.7 3 0 0 3 3 2 1 FERM central domain AAA_22 PF13401.1 GAM28344.1 - 0.026 14.6 0.0 0.23 11.6 0.0 2.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 GAM28344.1 - 0.18 11.6 3.2 4.6 7.0 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain AAA_16 PF13191.1 GAM28344.1 - 0.2 11.6 0.0 0.2 11.6 0.0 3.3 4 0 0 4 4 3 0 AAA ATPase domain Asp-B-Hydro_N PF05279.6 GAM28344.1 - 2.6 7.8 17.1 6.4 6.5 11.9 1.6 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Scramblase PF03803.10 GAM28345.1 - 0.00011 21.3 0.0 0.0004 19.5 0.0 1.8 1 1 0 1 1 1 1 Scramblase CAP_C PF08603.6 GAM28345.1 - 0.0015 17.9 0.5 0.43 9.9 0.0 3.8 3 1 0 3 3 3 1 Adenylate cyclase associated (CAP) C terminal Abhydrolase_9_N PF15420.1 GAM28347.1 - 0.09 12.5 1.2 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4117 PF13491.1 GAM28347.1 - 0.24 10.8 4.0 3 7.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) CopD PF05425.8 GAM28347.1 - 0.98 9.6 4.0 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Copper resistance protein D DUF2207 PF09972.4 GAM28347.1 - 5.2 5.5 6.7 2.6 6.5 1.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Polysacc_synt_C PF14667.1 GAM28347.1 - 6.1 6.6 14.2 0.31 10.8 0.4 2.6 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF3671 PF12420.3 GAM28347.1 - 9.7 6.2 13.2 1 9.3 1.8 2.6 3 0 0 3 3 3 0 Protein of unknown function Usp PF00582.21 GAM28348.1 - 6.5e-20 71.7 0.0 6.5e-20 71.7 0.0 1.5 2 0 0 2 2 2 1 Universal stress protein family HyaE PF07449.6 GAM28348.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Aminotran_1_2 PF00155.16 GAM28349.1 - 6.3e-61 206.3 0.0 7.6e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 GAM28349.1 - 2.6e-07 30.0 0.0 4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 GAM28349.1 - 0.0074 15.3 0.1 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 GAM28349.1 - 0.0088 14.7 0.1 0.05 12.2 0.0 2.0 1 1 0 1 1 1 1 Allinase Aminotran_3 PF00202.16 GAM28349.1 - 0.034 13.0 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III SLA_LP_auto_ag PF05889.8 GAM28349.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Glyco_hydro_20 PF00728.17 GAM28349.1 - 0.2 10.8 0.0 0.46 9.6 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, catalytic domain Kelch_6 PF13964.1 GAM28350.1 - 4.4e-15 55.1 10.4 1.5e-06 28.1 0.1 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM28350.1 - 1.1e-14 53.6 19.9 5.7e-05 22.5 0.5 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM28350.1 - 5.7e-12 45.2 9.9 7.1e-05 22.4 0.0 5.5 4 2 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM28350.1 - 4.1e-11 42.7 0.5 0.034 14.3 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM28350.1 - 4.6e-05 23.0 6.6 0.055 13.2 0.1 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 GAM28350.1 - 0.0028 17.5 15.3 0.07 13.0 0.2 4.8 5 0 0 5 5 5 2 Kelch motif Snf7 PF03357.16 GAM28351.1 - 4.5e-17 61.9 8.9 4.5e-17 61.9 6.1 2.4 2 0 0 2 2 2 1 Snf7 DUF3439 PF11921.3 GAM28351.1 - 0.014 15.0 8.3 0.014 15.0 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Phage_lysozyme PF00959.14 GAM28351.1 - 0.059 13.6 0.9 3 8.1 0.0 2.7 3 0 0 3 3 3 0 Phage lysozyme ACCA PF03255.9 GAM28351.1 - 1.3 8.5 5.1 0.62 9.6 0.2 2.5 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PilJ PF13675.1 GAM28351.1 - 1.8 8.8 8.8 1.5 9.1 0.9 3.2 4 1 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Mucin PF01456.12 GAM28351.1 - 2.1 8.1 23.3 0.22 11.2 12.5 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF2894 PF11445.3 GAM28351.1 - 3.7 7.7 9.2 0.98 9.6 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) FA_hydroxylase PF04116.8 GAM28354.1 - 1.2e-18 67.5 16.3 1.2e-18 67.5 11.3 3.2 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily Pkinase PF00069.20 GAM28355.1 - 1e-61 208.3 0.0 1.4e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28355.1 - 1.2e-19 70.4 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM28355.1 - 5.3e-07 29.6 0.0 7.9e-06 25.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM28355.1 - 0.004 16.5 0.3 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 GAM28355.1 - 0.016 14.7 0.2 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 GAM28355.1 - 0.044 12.7 0.0 0.26 10.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Myco_arth_vir_N PF09610.5 GAM28355.1 - 8.3 6.4 6.8 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Ras PF00071.17 GAM28357.1 - 6.8e-59 197.8 0.1 8e-59 197.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28357.1 - 3.7e-20 72.6 0.0 5.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28357.1 - 6.7e-18 64.5 0.0 8.1e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM28357.1 - 1.2e-09 38.1 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 GAM28357.1 - 1.1e-06 28.2 0.0 1.4e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM28357.1 - 0.0002 20.6 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 GAM28357.1 - 0.001 18.2 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 GAM28357.1 - 0.0018 17.5 0.2 0.0098 15.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 GAM28357.1 - 0.0077 15.8 0.0 0.023 14.2 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 GAM28357.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM28357.1 - 0.025 14.7 0.0 0.26 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain Lipase_3 PF01764.20 GAM28358.1 - 2.1e-13 50.1 0.0 5.1e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Miro PF08477.8 GAM28358.1 - 0.0079 16.6 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF2974 PF11187.3 GAM28358.1 - 0.075 12.3 0.2 0.28 10.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) OTU PF02338.14 GAM28358.1 - 0.079 13.5 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 OTU-like cysteine protease LSM PF01423.17 GAM28359.1 - 5.7e-19 67.4 0.5 6.9e-19 67.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 GAM28359.1 - 4.6e-06 26.4 0.1 6.4e-06 26.0 0.1 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF4407 PF14362.1 GAM28360.1 - 9.9e-05 21.4 16.0 0.00012 21.1 11.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FTZ PF03867.9 GAM28360.1 - 0.0044 16.3 5.2 0.007 15.6 3.6 1.3 1 0 0 1 1 1 1 Fushi tarazu (FTZ), N-terminal region Suf PF05843.9 GAM28360.1 - 0.26 10.9 15.9 0.44 10.2 11.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3043 PF11241.3 GAM28360.1 - 0.28 10.7 3.9 0.54 9.8 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Neur_chan_memb PF02932.11 GAM28360.1 - 0.42 10.4 3.4 0.42 10.4 2.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.8 GAM28360.1 - 0.96 9.2 29.0 1.1 9.0 20.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.1 GAM28360.1 - 3.6 7.7 10.2 5.3 7.1 7.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.8 GAM28360.1 - 5.1 7.1 25.6 0.019 15.0 7.7 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kelch_4 PF13418.1 GAM28361.1 - 1.5e-08 34.2 0.3 0.00019 21.1 0.0 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM28361.1 - 1e-05 24.9 9.3 0.005 16.3 0.5 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 GAM28361.1 - 0.0002 21.3 5.1 0.057 13.6 0.0 3.2 3 1 1 4 4 4 2 Kelch motif Kelch_2 PF07646.10 GAM28361.1 - 0.051 13.3 5.6 2.8 7.8 0.0 3.3 4 0 0 4 4 4 0 Kelch motif Kelch_5 PF13854.1 GAM28361.1 - 0.11 12.4 7.3 0.68 9.9 0.2 2.8 3 0 0 3 3 3 0 Kelch motif Arch_ATPase PF01637.13 GAM28362.1 - 0.001 18.8 0.1 0.0026 17.4 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase DUF1281 PF06924.6 GAM28362.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) Vinculin PF01044.14 GAM28363.1 - 6.8e-13 47.5 133.1 9.3e-09 33.8 22.0 6.7 2 1 4 6 6 6 3 Vinculin family LANC_like PF05147.8 GAM28363.1 - 0.028 12.9 2.1 0.067 11.7 0.0 2.8 3 0 0 3 3 3 0 Lanthionine synthetase C-like protein Ank_2 PF12796.2 GAM28364.1 - 1.5e-12 47.6 0.0 6.4e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28364.1 - 8.8e-11 41.0 1.3 0.00017 21.2 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 GAM28364.1 - 1.5e-06 27.8 0.5 0.0022 18.0 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 GAM28364.1 - 4.8e-06 26.6 0.7 0.00013 22.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM28364.1 - 3.6e-05 24.1 0.0 0.00019 21.8 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) F-box-like PF12937.2 GAM28364.1 - 0.0076 15.9 0.2 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like CBS PF00571.23 GAM28365.1 - 5.9e-25 86.7 0.0 4.5e-07 29.5 0.0 4.4 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 GAM28365.1 - 0.053 13.1 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 PB1 domain WD40 PF00400.27 GAM28366.1 - 3.2e-29 99.7 23.5 8.7e-06 25.4 0.5 10.3 9 1 0 9 9 9 8 WD domain, G-beta repeat HEAT_EZ PF13513.1 GAM28366.1 - 0.021 15.3 0.0 7.7 7.1 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat Coatomer_WDAD PF04053.9 GAM28366.1 - 0.12 11.1 0.1 7.5 5.2 0.0 2.5 3 0 0 3 3 3 0 Coatomer WD associated region Copine PF07002.11 GAM28367.1 - 7e-47 158.8 0.0 9.9e-47 158.3 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 GAM28367.1 - 3.8e-13 49.7 0.0 5.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 GAM28367.1 - 5.7e-06 26.5 0.0 7.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 GAM28367.1 - 0.018 14.7 0.1 0.034 13.8 0.0 1.5 2 0 0 2 2 2 0 von Willebrand factor type A domain TMF_DNA_bd PF12329.3 GAM28368.1 - 0.0013 18.5 5.3 0.0013 18.5 3.6 28.9 8 6 21 30 30 30 4 TATA element modulatory factor 1 DNA binding Filament PF00038.16 GAM28368.1 - 0.012 15.0 327.4 0.48 9.8 31.7 12.1 1 1 10 11 11 11 0 Intermediate filament protein ATG16 PF08614.6 GAM28368.1 - 0.11 12.2 329.1 0.023 14.5 16.7 15.5 1 1 15 16 16 16 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 GAM28368.1 - 0.38 9.1 284.0 0.0061 15.0 23.8 9.8 1 1 9 10 10 10 0 AAA domain Reo_sigmaC PF04582.7 GAM28368.1 - 3.5 6.7 157.3 0.026 13.7 0.8 14.2 2 1 14 16 16 16 0 Reovirus sigma C capsid protein Pkinase PF00069.20 GAM28369.1 - 9.1e-65 218.3 0.0 9.1e-65 218.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28369.1 - 1.7e-31 109.2 0.0 1.7e-31 109.2 0.0 2.8 2 2 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 GAM28369.1 - 0.59 8.8 0.0 0.59 8.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PAT1 PF09770.4 GAM28369.1 - 1.7 6.8 54.3 2.3 6.3 37.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Myb_DNA-binding PF00249.26 GAM28370.1 - 0.00015 21.7 0.2 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 GAM28370.1 - 0.0061 16.6 0.4 0.014 15.4 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain RasGAP PF00616.14 GAM28371.1 - 3.2e-15 56.3 3.5 1.9e-10 40.7 0.1 2.6 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase SH3_1 PF00018.23 GAM28372.1 - 2.5e-10 39.5 0.2 1.2e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 GAM28372.1 - 1.6e-08 33.9 0.4 2.2e-08 33.5 0.1 1.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 GAM28372.1 - 1.6e-05 24.3 0.0 1.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain His_biosynth PF00977.16 GAM28372.1 - 0.046 12.9 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Histidine biosynthesis protein Isochorismatase PF00857.15 GAM28374.1 - 2.6e-26 92.6 0.0 4.4e-26 91.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Neugrin PF06413.6 GAM28374.1 - 0.027 14.2 0.1 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Neugrin DUF2435 PF10363.4 GAM28375.1 - 0.00057 19.7 0.1 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 GAM28375.1 - 0.0009 18.6 1.9 0.0012 18.2 0.4 1.9 2 1 0 2 2 2 1 CLASP N terminal AAA_13 PF13166.1 GAM28375.1 - 0.0012 17.3 6.2 0.0026 16.3 4.3 1.4 1 0 0 1 1 1 1 AAA domain HEAT PF02985.17 GAM28375.1 - 0.026 14.5 0.9 31 5.0 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DUF2353 PF09789.4 GAM28375.1 - 0.028 13.6 14.9 0.06 12.5 10.3 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HEAT_2 PF13646.1 GAM28375.1 - 0.03 14.6 0.1 6.4 7.1 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats Peptidase_S64 PF08192.6 GAM28375.1 - 0.12 10.7 14.7 0.0057 15.0 5.7 1.8 2 0 0 2 2 2 0 Peptidase family S64 Exonuc_VII_L PF02601.10 GAM28375.1 - 1.2 8.2 15.3 0.21 10.7 7.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3439 PF11921.3 GAM28375.1 - 1.5 8.5 6.1 3.7 7.3 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DivIC PF04977.10 GAM28375.1 - 2.2 7.8 11.9 3.7 7.1 0.3 3.2 2 1 1 3 3 3 0 Septum formation initiator APG6 PF04111.7 GAM28375.1 - 3.2 6.7 17.0 7 5.5 11.8 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_32 PF13654.1 GAM28375.1 - 3.9 6.0 14.2 2.7 6.5 7.7 1.9 2 0 0 2 2 2 0 AAA domain Flagellar_rod PF05149.7 GAM28375.1 - 9.8 5.2 20.2 0.86 8.7 6.6 2.4 1 1 1 2 2 2 0 Paraflagellar rod protein HEAT PF02985.17 GAM28376.1 - 0.13 12.4 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat OmdA PF13376.1 GAM28377.1 - 1.3e-06 27.9 0.3 3.2e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated INTS5_C PF14838.1 GAM28378.1 - 1.9e-23 82.7 9.2 3.4e-22 78.5 0.1 2.9 2 1 0 2 2 2 2 Integrator complex subunit 5 C-terminus INTS5_N PF14837.1 GAM28378.1 - 4.6e-05 22.9 1.4 4.6e-05 22.9 1.0 3.1 3 0 0 3 3 3 1 Integrator complex subunit 5 N-terminus Zip PF02535.17 GAM28378.1 - 1 8.2 10.0 2 7.3 6.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3439 PF11921.3 GAM28378.1 - 5.9 6.6 11.0 27 4.5 4.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) TFIIA PF03153.8 GAM28378.1 - 7.2 6.4 17.8 0.53 10.1 7.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Amnionless PF14828.1 GAM28379.1 - 0.011 14.2 1.6 0.2 10.0 0.1 2.5 2 0 0 2 2 2 0 Amnionless T2SN PF01203.14 GAM28379.1 - 0.021 14.3 0.2 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein N RNase_T PF00929.19 GAM28380.1 - 2.7e-20 73.2 0.0 7.4e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Exonuclease Glyoxalase PF00903.20 GAM28380.1 - 6.8e-09 35.7 0.0 1.4e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 GAM28380.1 - 5.5e-08 33.3 0.0 1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain RNase_H_2 PF13482.1 GAM28380.1 - 0.041 13.6 0.0 0.35 10.6 0.0 2.1 1 1 0 1 1 1 0 RNase_H superfamily 2OG-FeII_Oxy_2 PF13532.1 GAM28381.1 - 2.1e-26 92.9 0.1 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIRP PF06584.8 GAM28382.1 - 6.8e-21 74.1 1.2 2.4e-20 72.4 0.9 2.0 1 0 0 1 1 1 1 DIRP Myb_DNA-binding PF00249.26 GAM28382.1 - 0.00015 21.7 0.1 0.00035 20.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain BAF1_ABF1 PF04684.8 GAM28382.1 - 0.00039 19.4 7.4 0.00039 19.4 5.1 3.7 3 1 1 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor Ras PF00071.17 GAM28383.1 - 1.6e-53 180.4 0.1 1.9e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28383.1 - 9.7e-21 74.4 0.0 1.4e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28383.1 - 3.9e-15 55.5 0.0 4.4e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 GAM28383.1 - 0.00023 21.1 0.0 0.0004 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM28383.1 - 0.00084 18.5 0.0 0.00094 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM28383.1 - 0.0013 18.2 0.0 0.0049 16.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM28383.1 - 0.0035 16.5 0.0 0.0075 15.5 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 GAM28383.1 - 0.017 14.6 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SET PF00856.23 GAM28384.1 - 0.00012 22.4 0.0 0.003 17.8 0.0 2.6 1 1 0 1 1 1 1 SET domain Nucleocap_ssRNA PF11128.3 GAM28384.1 - 0.068 12.6 0.3 4.7 6.6 0.0 2.7 2 1 1 3 3 3 0 Plant viral coat protein nucleocapsid GATA PF00320.22 GAM28385.1 - 9.4e-16 56.8 2.1 2.9e-15 55.2 1.5 1.9 1 0 0 1 1 1 1 GATA zinc finger SR-25 PF10500.4 GAM28385.1 - 2.1 7.7 8.9 1.1 8.7 3.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_4 PF02390.12 GAM28387.1 - 1.9e-36 125.0 0.0 2.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 GAM28387.1 - 2e-06 27.4 0.1 3.1e-06 26.8 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM28387.1 - 0.00081 19.9 0.0 0.00096 19.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 GAM28387.1 - 0.0084 15.1 0.0 0.017 14.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 GAM28387.1 - 0.0093 16.3 0.0 0.027 14.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM28387.1 - 0.0097 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF2393 PF09624.5 GAM28387.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DOT1 PF08123.8 GAM28387.1 - 0.087 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 YpzG PF14139.1 GAM28387.1 - 0.095 12.6 0.1 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 YpzG-like protein BTB_2 PF02214.17 GAM28388.1 - 8.3e-13 48.3 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 GAM28388.1 - 0.036 14.0 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain DUF4452 PF14618.1 GAM28389.1 - 0.017 14.9 2.9 0.024 14.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DUF905 PF06006.7 GAM28389.1 - 1.4 8.3 4.3 0.73 9.2 1.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Rcd1 PF04078.8 GAM28390.1 - 2.2e-121 403.6 1.5 2.8e-121 403.3 1.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Kinesin PF00225.18 GAM28391.1 - 3.2e-106 354.8 0.2 3.2e-106 354.8 0.2 2.7 3 0 0 3 3 3 1 Kinesin motor domain PH PF00169.24 GAM28391.1 - 1.1e-09 38.3 0.3 6.4e-09 35.9 0.2 2.4 1 0 0 1 1 1 1 PH domain FHA PF00498.21 GAM28391.1 - 3.3e-07 30.3 0.2 2.3e-06 27.6 0.1 2.5 2 0 0 2 2 2 1 FHA domain DUF3694 PF12473.3 GAM28391.1 - 5.8e-07 29.2 4.8 8.8e-07 28.6 0.0 3.6 4 1 0 4 4 4 1 Kinesin protein KIF1B PF12423.3 GAM28391.1 - 0.00035 20.5 3.6 0.0098 15.9 0.6 2.8 2 0 0 2 2 2 1 Kinesin protein 1B PH_8 PF15409.1 GAM28391.1 - 0.0013 18.7 1.1 0.0028 17.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain FNIP PF05725.7 GAM28394.1 - 7.3e-72 237.0 24.6 3.2e-12 46.1 0.2 8.3 5 1 2 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 GAM28394.1 - 0.00035 20.4 5.5 1.7 8.6 0.2 5.8 5 2 2 7 7 7 2 Protein of unknown function (DUF1769) Beta_helix PF13229.1 GAM28395.1 - 0.0019 17.9 25.3 0.0019 17.9 17.5 1.8 1 1 1 2 2 2 2 Right handed beta helix region Podoplanin PF05808.6 GAM28395.1 - 0.015 14.8 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Podoplanin Pentapeptide_4 PF13599.1 GAM28395.1 - 0.15 11.8 8.2 1 9.1 0.4 2.7 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) EphA2_TM PF14575.1 GAM28395.1 - 0.17 12.3 0.7 0.31 11.4 0.5 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FNIP PF05725.7 GAM28396.1 - 6.6e-53 176.4 24.7 4.5e-10 39.3 0.1 7.9 5 1 4 9 9 9 8 FNIP Repeat LRR_5 PF13306.1 GAM28396.1 - 7.1e-05 22.5 2.2 0.029 14.0 0.6 4.1 3 2 2 5 5 5 3 Leucine rich repeats (6 copies) FNIP PF05725.7 GAM28397.1 - 1.2e-44 149.9 17.3 3.2e-11 43.0 0.1 7.6 3 2 6 9 9 9 8 FNIP Repeat NUDIX PF00293.23 GAM28398.1 - 1.4e-11 44.1 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain ACDC PF14733.1 GAM28398.1 - 0.11 12.6 0.1 0.17 12.0 0.0 1.4 1 1 0 1 1 1 0 AP2-coincident C-terminal DUF479 PF04336.7 GAM28399.1 - 0.0091 16.0 0.1 0.19 11.8 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function, DUF479 FNIP PF05725.7 GAM28400.1 - 7.2e-52 173.1 32.9 1.2e-14 53.9 0.9 8.4 8 1 2 10 10 10 8 FNIP Repeat FNIP PF05725.7 GAM28401.1 - 9e-76 249.6 61.7 4.6e-16 58.4 0.8 12.5 9 3 5 14 14 14 11 FNIP Repeat DUF1769 PF08588.5 GAM28401.1 - 1.9e-05 24.5 7.2 0.17 11.8 0.0 6.4 4 2 2 6 6 6 2 Protein of unknown function (DUF1769) Coiled PF05710.7 GAM28402.1 - 4.1e-11 43.1 13.5 5e-11 42.9 9.4 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.7 GAM28403.1 - 7.7e-07 29.4 13.2 9e-07 29.2 9.2 1.1 1 0 0 1 1 1 1 Coiled coil RRM_1 PF00076.17 GAM28404.1 - 1.8e-10 40.2 0.2 4.7e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28404.1 - 1.8e-08 34.2 0.1 3.4e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 GAM28404.1 - 0.0005 19.7 0.0 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 GAM28404.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 GAM28405.1 - 7.6e-47 159.6 0.3 7.1e-46 156.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28405.1 - 3.6e-30 104.9 0.0 2.5e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM28405.1 - 0.015 14.3 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RasGEF_N_2 PF14663.1 GAM28407.1 - 0.043 13.7 0.3 0.18 11.7 0.0 2.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Metal_resist PF13801.1 GAM28407.1 - 0.081 12.9 0.2 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Heavy-metal resistance LRS4 PF10422.4 GAM28407.1 - 0.12 11.6 3.4 0.049 12.9 0.7 1.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 TPR_12 PF13424.1 GAM28407.1 - 0.13 12.1 3.5 0.35 10.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat IncA PF04156.9 GAM28407.1 - 7.9 6.0 8.7 0.98 8.9 0.2 2.6 2 1 0 2 2 2 0 IncA protein 7tm_3 PF00003.17 GAM28408.1 - 4e-26 91.8 36.8 4e-26 91.8 25.5 1.6 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR RhoGAP PF00620.22 GAM28409.1 - 1.6e-28 99.2 0.0 7.8e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.15 GAM28410.1 - 5.5e-44 150.1 4.4 5.5e-44 150.1 3.0 2.6 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM28410.1 - 3.1e-17 62.6 1.0 2.4e-15 56.6 0.1 3.0 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 GAM28410.1 - 1.7e-10 40.6 0.3 1.7e-10 40.6 0.2 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 GAM28410.1 - 8.9e-08 32.3 5.0 2.4e-05 24.5 1.7 4.0 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM28410.1 - 2.4e-06 27.5 0.3 6.5e-06 26.1 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain NAD_binding_6 PF08030.7 GAM28411.1 - 8.4e-27 93.9 0.6 2.5e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM28411.1 - 2.8e-22 78.5 0.0 5.9e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 GAM28411.1 - 2.9e-14 53.2 5.9 2.9e-14 53.2 4.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_6 PF13405.1 GAM28411.1 - 2.4e-09 36.3 3.4 0.0019 17.9 0.6 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 GAM28411.1 - 4.6e-09 36.2 3.6 1.4e-08 34.7 2.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM28411.1 - 6.7e-09 35.2 0.6 2.5e-08 33.4 0.2 2.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 GAM28411.1 - 3.2e-08 32.2 4.2 3e-05 23.0 1.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 GAM28411.1 - 1.2e-06 27.5 3.6 1.7e-06 27.1 1.2 2.2 2 0 0 2 2 2 1 EF hand FAD_binding_6 PF00970.19 GAM28411.1 - 0.0002 21.4 0.0 0.0005 20.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain HATPase_c PF02518.21 GAM28411.1 - 0.012 15.2 0.0 0.12 12.0 0.0 2.6 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ORC6 PF05460.8 GAM28411.1 - 0.64 9.0 5.0 1.1 8.3 3.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NUDIX PF00293.23 GAM28412.1 - 9.7e-12 44.6 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain GBP_C PF02841.9 GAM28412.1 - 0.052 12.7 0.2 0.052 12.7 0.2 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain NUDIX_4 PF14815.1 GAM28412.1 - 0.067 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 NUDIX domain Ank_2 PF12796.2 GAM28413.1 - 4e-42 142.4 4.6 3.8e-08 33.5 0.0 5.7 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28413.1 - 3.8e-37 124.2 6.1 3.2e-05 23.5 0.0 9.2 8 1 1 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 GAM28413.1 - 9.6e-37 124.7 4.5 9.8e-08 32.3 0.0 6.8 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28413.1 - 3.9e-29 100.0 4.3 6.2e-08 32.6 0.1 7.9 4 2 4 8 8 8 6 Ankyrin repeats (many copies) BTB PF00651.26 GAM28413.1 - 8e-18 64.4 1.8 9.7e-07 28.7 0.0 4.7 4 0 0 4 4 4 4 BTB/POZ domain Ank_3 PF13606.1 GAM28413.1 - 4.3e-16 57.3 11.0 0.0014 18.7 0.0 9.1 10 1 1 11 11 11 5 Ankyrin repeat PCNA_N PF00705.13 GAM28414.1 - 4e-51 171.8 0.2 1.3e-50 170.1 0.4 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 GAM28414.1 - 4.1e-46 156.0 0.2 1.9e-45 153.8 0.0 1.9 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 GAM28414.1 - 0.00011 21.4 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 GAM28414.1 - 0.00081 18.4 0.0 0.0017 17.3 0.0 1.5 1 1 0 1 1 1 1 Hus1-like protein Peptidase_M28 PF04389.12 GAM28415.1 - 8.4e-19 67.9 0.1 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 GAM28415.1 - 4.9e-08 32.6 0.1 8.7e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Synaptobrevin PF00957.16 GAM28415.1 - 0.052 13.1 0.5 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 Synaptobrevin Na_H_Exchanger PF00999.16 GAM28416.1 - 4.6e-69 232.7 44.1 6.2e-69 232.3 30.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.7 GAM28416.1 - 8.5e-06 25.3 5.3 8.5e-06 25.3 3.7 2.3 3 1 0 3 3 3 1 Predicted Permease Membrane Region Usp PF00582.21 GAM28416.1 - 0.0015 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family Glyco_hydro_7 PF00840.15 GAM28417.1 - 7.5e-207 686.8 17.7 8.6e-207 686.6 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CPSF_A PF03178.10 GAM28418.1 - 4.6e-65 219.8 0.3 8.6e-65 218.9 0.2 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 GAM28418.1 - 2.4e-23 82.0 0.4 5.2e-23 80.9 0.2 1.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Corona_NS2 PF04753.7 GAM28418.1 - 0.0025 17.7 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 Coronavirus non-structural protein NS2 FAM176 PF14851.1 GAM28418.1 - 5.8 6.5 11.7 0.75 9.4 0.5 3.7 4 0 0 4 4 4 0 FAM176 family Ank_2 PF12796.2 GAM28419.1 - 3.7e-112 366.9 21.3 2.5e-21 75.8 0.5 5.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28419.1 - 2.1e-65 213.4 14.1 3.9e-09 35.8 0.2 9.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 GAM28419.1 - 4.2e-51 170.4 6.9 1.4e-09 38.2 0.0 7.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28419.1 - 8.1e-44 143.2 8.8 5e-05 23.1 0.1 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 GAM28419.1 - 2e-42 142.2 9.5 1.2e-09 38.0 0.1 7.5 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Homeobox PF00046.24 GAM28419.1 - 2.1e-19 68.9 1.5 5.6e-19 67.5 1.0 1.8 1 0 0 1 1 1 1 Homeobox domain Nsp1_C PF05064.8 GAM28420.1 - 1.1e-23 83.1 13.3 1.1e-23 83.1 9.2 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region HTH_22 PF13309.1 GAM28420.1 - 0.16 11.7 0.6 0.47 10.2 0.4 1.8 1 0 0 1 1 1 0 HTH domain Nucleoporin_FG PF13634.1 GAM28420.1 - 0.5 10.6 212.9 0.068 13.3 27.4 6.8 1 1 4 5 5 5 0 Nucleoporin FG repeat region Laminin_II PF06009.7 GAM28420.1 - 0.97 9.1 19.1 3.2 7.5 4.4 2.3 1 1 1 2 2 2 0 Laminin Domain II Syntaxin PF00804.20 GAM28420.1 - 2 8.5 19.5 0.44 10.7 4.9 2.4 1 1 1 2 2 2 0 Syntaxin FANCI_S2 PF14676.1 GAM28420.1 - 3.7 7.4 5.0 0.59 10.0 0.7 1.6 2 0 0 2 2 2 0 FANCI solenoid 2 DUF1664 PF07889.7 GAM28420.1 - 3.9 7.2 8.1 1.9 8.2 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Prp18 PF02840.10 GAM28420.1 - 4.9 6.9 11.1 0.69 9.7 3.4 2.1 1 1 1 2 2 2 0 Prp18 domain TPR_MLP1_2 PF07926.7 GAM28421.1 - 1.1e-21 76.9 17.4 1.1e-21 76.9 12.1 14.4 5 4 6 11 11 11 4 TPR/MLP1/MLP2-like protein Cyclin PF08613.6 GAM28422.1 - 4.9e-21 75.7 0.4 7.7e-21 75.0 0.0 1.5 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM28422.1 - 2.8e-10 39.8 0.0 5e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Lyase_8 PF02278.13 GAM28425.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain BCNT PF07572.7 GAM28425.1 - 0.0097 15.8 0.2 0.028 14.3 0.1 1.8 1 0 0 1 1 1 1 Bucentaur or craniofacial development Herpes_capsid PF06112.6 GAM28425.1 - 2 8.4 12.3 0.018 15.0 2.8 1.8 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein RhoGEF PF00621.15 GAM28426.1 - 5.1e-40 137.2 0.4 8.4e-40 136.5 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain ARL2_Bind_BART PF11527.3 GAM28426.1 - 0.039 13.7 1.1 5.7 6.7 0.0 2.7 2 2 0 2 2 2 0 The ARF-like 2 binding protein BART Ada3 PF10198.4 GAM28426.1 - 0.36 10.5 3.5 1.6 8.4 0.1 2.6 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 DUF1764 PF08576.5 GAM28427.1 - 0.042 14.6 0.2 0.042 14.6 0.1 3.9 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) DUF2964 PF11177.3 GAM28430.1 - 0.095 12.6 1.1 0.18 11.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Tubulin_3 PF14881.1 GAM28431.1 - 1.9e-26 92.6 0.4 4e-26 91.6 0.3 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 GAM28431.1 - 4.5e-26 91.1 1.2 4.5e-25 87.9 0.0 2.8 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 GAM28431.1 - 1.8e-10 40.9 1.2 6.3e-06 26.1 0.0 2.7 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain Stk19 PF10494.4 GAM28432.1 - 0.012 14.9 0.9 0.012 14.9 0.7 1.7 2 0 0 2 2 2 0 Serine-threonine protein kinase 19 TBPIP PF07106.8 GAM28432.1 - 0.13 11.7 10.0 0.05 13.1 1.0 2.5 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ORC6 PF05460.8 GAM28432.1 - 0.5 9.4 15.0 1.8 7.6 7.6 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ank_2 PF12796.2 GAM28433.1 - 1.9e-28 98.6 5.5 3.2e-07 30.6 0.0 7.1 3 3 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28433.1 - 3.7e-20 71.8 11.3 1.6e-06 28.4 0.0 8.0 8 0 0 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28433.1 - 1.2e-19 68.4 12.4 0.15 12.3 0.0 13.6 12 3 3 15 15 15 5 Ankyrin repeat Ank_5 PF13857.1 GAM28433.1 - 5e-18 64.7 11.5 0.041 14.1 0.0 11.3 7 3 5 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.25 GAM28433.1 - 4.4e-15 54.6 12.9 0.23 11.3 0.0 12.0 15 1 0 15 15 15 3 Ankyrin repeat Rsm1 PF08600.5 GAM28433.1 - 0.093 12.5 0.0 0.29 11.0 0.0 1.8 1 0 0 1 1 1 0 Rsm1-like Mic1 PF07035.7 GAM28434.1 - 8.7e-37 126.0 4.8 1.6e-36 125.1 3.3 1.4 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like SGT1 PF07093.6 GAM28435.1 - 7.8e-134 447.2 12.9 1.1e-133 446.8 8.9 1.1 1 0 0 1 1 1 1 SGT1 protein HR_lesion PF05514.6 GAM28435.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 HR-like lesion-inducing BUD22 PF09073.5 GAM28435.1 - 0.26 10.3 15.9 0.44 9.5 11.0 1.4 1 0 0 1 1 1 0 BUD22 Ribonuc_L-PSP PF01042.16 GAM28436.1 - 8.7e-29 99.7 0.1 1.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF3186 PF11382.3 GAM28436.1 - 0.01 15.0 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) PPR_2 PF13041.1 GAM28437.1 - 5.2e-16 58.3 17.8 1.6e-05 24.7 0.0 5.3 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.1 GAM28437.1 - 5.4e-15 54.3 2.7 0.037 14.3 0.0 6.1 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.15 GAM28437.1 - 1.2e-14 53.1 10.8 0.011 15.6 0.0 5.6 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 GAM28437.1 - 2.9e-07 29.8 2.3 0.14 11.6 0.0 4.7 3 1 1 4 4 4 3 PPR repeat DUF566 PF04484.7 GAM28437.1 - 0.15 11.5 8.7 0.27 10.6 6.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) DAP10 PF07213.6 GAM28438.1 - 3.5 7.4 6.7 6.5 6.5 4.7 1.6 1 1 0 1 1 1 0 DAP10 membrane protein DUF4274 PF14096.1 GAM28442.1 - 7.1 6.5 7.5 1.4e+02 2.3 0.1 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4274) Kelch_6 PF13964.1 GAM28443.1 - 9.5e-13 47.7 11.6 0.0017 18.4 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 GAM28443.1 - 1.7e-11 43.6 11.9 1.4e-07 31.1 0.1 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 GAM28443.1 - 5.3e-09 35.4 3.5 0.11 12.2 0.2 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 GAM28443.1 - 6.8e-09 35.1 14.6 0.0038 16.7 0.3 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 GAM28443.1 - 3.4e-07 30.0 5.9 0.41 10.6 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 GAM28443.1 - 0.00035 20.6 3.4 4.8 7.4 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain ArgK PF03308.11 GAM28444.1 - 6.3e-89 297.2 0.1 1.2e-88 296.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 GAM28444.1 - 5e-07 29.3 0.0 1.3e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 GAM28444.1 - 0.00043 19.7 0.1 0.00098 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 GAM28444.1 - 0.0013 18.3 0.1 0.0052 16.3 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 GAM28444.1 - 0.0025 18.6 0.3 0.0066 17.2 0.2 1.7 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 GAM28444.1 - 0.012 15.2 0.2 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.1 GAM28444.1 - 0.018 15.3 0.4 0.039 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 GAM28444.1 - 0.023 14.1 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAM28444.1 - 0.042 13.7 0.7 0.14 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 GAM28444.1 - 0.043 14.1 1.2 0.091 13.0 0.0 2.1 2 1 1 3 3 3 0 ABC transporter AAA_18 PF13238.1 GAM28444.1 - 0.081 13.2 1.9 0.16 12.3 0.1 2.4 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 GAM28444.1 - 0.085 11.9 0.1 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin PPV_E1_C PF00519.12 GAM28444.1 - 0.1 11.1 1.4 0.75 8.3 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase AAA_30 PF13604.1 GAM28444.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM28444.1 - 0.21 11.7 1.3 0.84 9.7 0.1 2.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 GAM28444.1 - 0.26 11.2 4.5 0.22 11.4 0.1 2.7 2 2 0 2 2 2 0 50S ribosome-binding GTPase PIP5K PF01504.13 GAM28446.1 - 3.1e-63 213.2 3.6 4.2e-63 212.8 2.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase 7tm_1 PF00001.16 GAM28446.1 - 2.5e-09 36.6 2.7 3.7e-09 36.0 1.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.12 GAM28446.1 - 2.4e-07 29.8 7.6 9.4e-07 27.9 5.2 1.8 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.19 GAM28446.1 - 0.0077 15.3 8.9 0.01 14.9 3.8 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) RRM_6 PF14259.1 GAM28447.1 - 9.4e-40 134.4 0.0 3.3e-13 49.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 GAM28447.1 - 3.3e-29 100.3 0.0 4.8e-09 35.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM28447.1 - 2.7e-08 33.5 0.0 0.061 13.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deaminase PF00962.17 GAM28448.1 - 3.2e-82 276.1 0.0 1.1e-70 238.1 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase FNIP PF05725.7 GAM28449.1 - 7.1e-49 163.5 10.2 1.1e-12 47.6 0.3 5.5 5 0 0 5 5 5 5 FNIP Repeat DUF3752 PF12572.3 GAM28449.1 - 1.4e-20 73.9 14.5 1.4e-20 73.9 10.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Pkinase_Tyr PF07714.12 GAM28453.1 - 5.9e-56 189.4 0.0 9.2e-56 188.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM28453.1 - 7.3e-54 182.6 0.0 1.5e-53 181.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TipAS PF07739.8 GAM28455.1 - 0.94 9.8 5.3 2.4 8.4 3.7 1.8 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain PAP2 PF01569.16 GAM28456.1 - 7.6e-18 64.4 6.6 7.6e-18 64.4 4.6 2.3 2 1 0 2 2 2 1 PAP2 superfamily DUF443 PF04276.7 GAM28456.1 - 0.0044 16.4 0.5 0.0044 16.4 0.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF443) Med13_N PF11597.3 GAM28457.1 - 0.049 12.3 8.1 0.07 11.8 5.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Tox-REase-2 PF15646.1 GAM28457.1 - 1 9.2 6.4 4.7 7.1 4.3 2.1 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 MCLC PF05934.6 GAM28457.1 - 2.9 6.0 5.6 2.4 6.3 2.4 1.8 2 0 0 2 2 2 0 Mid-1-related chloride channel (MCLC) PAT1 PF09770.4 GAM28457.1 - 3.6 5.6 38.4 5.3 5.1 26.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 GAM28457.1 - 7.1 4.3 12.9 10 3.8 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kelch_3 PF13415.1 GAM28458.1 - 9e-37 124.4 4.3 4.2e-09 36.3 0.0 7.4 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM28458.1 - 4.1e-35 119.2 10.7 3.5e-11 42.6 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM28458.1 - 1e-33 114.7 5.4 2.2e-06 27.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM28458.1 - 9.3e-31 105.1 7.7 2.4e-06 26.9 0.0 6.4 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 GAM28458.1 - 1.1e-29 101.3 8.2 8.3e-06 25.7 0.0 6.3 3 2 4 7 7 7 5 Kelch motif Kelch_2 PF07646.10 GAM28458.1 - 3.3e-22 77.3 2.4 2.7e-07 30.0 0.1 6.5 6 0 0 6 6 6 4 Kelch motif F-box-like PF12937.2 GAM28458.1 - 1.7e-06 27.6 0.5 4.6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM28458.1 - 0.00014 21.4 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain RAG2 PF03089.9 GAM28458.1 - 0.043 12.5 0.0 12 4.4 0.0 3.5 3 1 1 4 4 4 0 Recombination activating protein 2 Elongin_A PF06881.6 GAM28458.1 - 0.16 12.3 0.5 0.27 11.6 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A EGF_2 PF07974.8 GAM28459.1 - 0.00027 21.0 16.3 0.00053 20.0 11.3 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 GAM28459.1 - 1.5 9.0 6.8 6.4 7.0 4.7 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF SieB PF14163.1 GAM28460.1 - 0.0088 15.6 0.2 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Superinfection exclusion protein B DUF2668 PF10873.3 GAM28460.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Vpu PF00558.14 GAM28460.1 - 0.096 12.2 1.0 0.17 11.4 0.7 1.4 1 0 0 1 1 1 0 Vpu protein ABC2_membrane_2 PF12679.2 GAM28460.1 - 0.2 10.4 1.7 0.34 9.7 1.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Ras PF00071.17 GAM28461.1 - 1.7e-54 183.5 0.0 2.1e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28461.1 - 3.1e-14 53.5 0.0 5.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28461.1 - 9.4e-09 34.7 0.0 1.2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM28461.1 - 0.00097 18.6 0.0 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM28461.1 - 0.0026 17.6 0.0 0.0046 16.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase LcrG PF07216.7 GAM28461.1 - 0.008 16.1 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 LcrG protein FeoB_N PF02421.13 GAM28461.1 - 0.03 13.5 0.0 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.12 GAM28461.1 - 0.12 11.7 0.0 0.47 9.8 0.0 2.0 3 0 0 3 3 3 0 IstB-like ATP binding protein CH PF00307.26 GAM28462.1 - 2.6e-37 127.1 0.2 1.4e-18 66.9 0.1 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain Cortex-I_coil PF09304.5 GAM28462.1 - 1.7e-32 111.6 22.5 1.7e-32 111.6 15.6 2.9 1 1 0 2 2 2 1 Cortexillin I, coiled coil CAMSAP_CH PF11971.3 GAM28462.1 - 4.5e-05 23.0 0.0 0.055 13.1 0.0 2.8 2 1 0 2 2 2 2 CAMSAP CH domain RBD-FIP PF09457.5 GAM28462.1 - 0.014 15.2 2.9 0.014 15.2 2.0 3.4 4 0 0 4 4 4 0 FIP domain GPAT_N PF14829.1 GAM28462.1 - 0.075 12.7 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ERM PF00769.14 GAM28462.1 - 0.11 11.9 24.2 0.053 13.0 5.8 1.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4600 PF15372.1 GAM28462.1 - 1 9.5 20.5 10 6.3 4.7 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) DUF4635 PF15466.1 GAM28462.1 - 1.9 7.7 11.8 8.4 5.6 4.3 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4635) Macoilin PF09726.4 GAM28462.1 - 2.8 6.1 17.6 3.9 5.6 12.2 1.3 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 GAM28462.1 - 3.3 6.6 20.2 0.96 8.4 11.4 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 GAM28462.1 - 3.7 5.2 8.4 5.4 4.7 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nipped-B_C PF12830.2 GAM28463.1 - 3.5e-41 140.9 3.7 3.5e-41 140.9 2.6 3.8 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 GAM28463.1 - 3.8e-10 39.5 8.4 1.1e-09 38.0 0.3 3.6 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 GAM28463.1 - 0.00034 20.4 1.9 2.4 8.4 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat PHD PF00628.24 GAM28463.1 - 0.0018 17.9 8.9 0.0055 16.3 6.2 1.9 1 0 0 1 1 1 1 PHD-finger CDC45 PF02724.9 GAM28463.1 - 2 6.3 30.4 0.27 9.2 13.9 3.2 3 0 0 3 3 3 0 CDC45-like protein Pkinase PF00069.20 GAM28464.1 - 3.3e-53 180.4 0.0 6.7e-53 179.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28464.1 - 4.1e-53 180.1 0.1 6.4e-53 179.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 GAM28464.1 - 1.7e-18 66.7 1.8 1.2e-17 64.0 1.2 2.4 1 1 0 1 1 1 1 Regulator of G protein signaling domain APH PF01636.18 GAM28464.1 - 0.019 14.6 0.0 0.4 10.3 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family DnaJ-X PF14308.1 GAM28465.1 - 1.5e-31 109.2 1.3 6.3e-31 107.2 0.2 2.3 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 GAM28465.1 - 1e-26 92.4 6.6 1e-26 92.4 4.6 2.2 2 0 0 2 2 2 1 DnaJ domain Armet PF10208.4 GAM28465.1 - 0.02 14.5 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding TPR_20 PF14561.1 GAM28465.1 - 0.058 13.5 1.3 0.36 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Vpu PF00558.14 GAM28466.1 - 0.2 11.2 0.6 0.32 10.5 0.4 1.3 1 0 0 1 1 1 0 Vpu protein Vpu PF00558.14 GAM28467.1 - 0.049 13.1 0.7 0.091 12.3 0.5 1.4 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.8 GAM28467.1 - 0.13 12.4 13.5 0.25 11.5 9.4 1.5 1 0 0 1 1 1 0 EGF-like domain DDE_Tnp_1_7 PF13843.1 GAM28468.1 - 1.5e-33 116.3 0.0 2.4e-33 115.6 0.0 1.3 1 1 0 1 1 1 1 Transposase IS4 DUF4404 PF14357.1 GAM28468.1 - 0.13 12.7 0.8 11 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) EGF_2 PF07974.8 GAM28469.1 - 1.8 8.7 17.7 0.33 11.1 9.5 1.8 2 0 0 2 2 2 0 EGF-like domain Vpu PF00558.14 GAM28470.1 - 0.044 13.3 0.8 0.083 12.4 0.5 1.4 1 0 0 1 1 1 0 Vpu protein EGF_2 PF07974.8 GAM28471.1 - 0.0051 16.9 15.6 0.0091 16.1 10.8 1.4 1 0 0 1 1 1 1 EGF-like domain Vpu PF00558.14 GAM28471.1 - 0.052 13.1 1.7 0.091 12.3 1.2 1.3 1 0 0 1 1 1 0 Vpu protein DAP10 PF07213.6 GAM28471.1 - 0.085 12.6 0.8 0.2 11.4 0.5 1.6 1 0 0 1 1 1 0 DAP10 membrane protein EGF PF00008.22 GAM28471.1 - 2.8 8.0 11.6 6.6 6.8 8.1 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.8 GAM28472.1 - 0.0015 18.6 15.3 0.0015 18.6 10.6 1.8 2 0 0 2 2 2 1 EGF-like domain Ribosomal_L19 PF01245.15 GAM28472.1 - 0.032 14.0 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L19 Vpu PF00558.14 GAM28472.1 - 0.18 11.3 0.3 0.42 10.2 0.2 1.5 1 0 0 1 1 1 0 Vpu protein EGF PF00008.22 GAM28472.1 - 0.6 10.1 11.9 1.8 8.6 8.2 1.9 1 0 0 1 1 1 0 EGF-like domain Glyco_hydro_18 PF00704.23 GAM28473.1 - 3.5e-05 23.4 0.3 0.00015 21.2 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 Methyltransf_32 PF13679.1 GAM28473.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 GAM28475.1 - 6.2e-59 199.2 0.0 4e-58 196.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28475.1 - 2.3e-57 194.0 0.0 3.4e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 GAM28475.1 - 6.4e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL SKG6 PF08693.5 GAM28475.1 - 0.11 11.7 0.6 0.3 10.4 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.18 GAM28475.1 - 0.69 9.5 0.0 1.2 8.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tir_receptor_C PF07489.6 GAM28476.1 - 0.52 10.0 12.7 1.2 8.8 8.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus zf-RING_2 PF13639.1 GAM28478.1 - 8.6e-08 31.8 14.0 8.6e-08 31.8 9.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-B_box PF00643.19 GAM28478.1 - 1.1e-07 31.5 10.6 1.1e-07 31.5 7.3 2.9 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4_2 PF13923.1 GAM28478.1 - 0.00017 21.5 15.7 0.00017 21.5 10.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 GAM28478.1 - 0.0013 18.3 12.0 0.0013 18.3 8.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM28478.1 - 0.0022 18.0 11.5 0.0022 18.0 8.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 GAM28478.1 - 9.5 6.0 12.6 0.32 10.7 3.9 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ank_2 PF12796.2 GAM28479.1 - 0.00032 20.9 0.2 0.72 10.2 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28479.1 - 0.062 13.5 1.5 4.2 7.7 0.0 3.9 3 2 3 6 6 6 0 Ankyrin repeats (many copies) Epsilon_antitox PF08998.6 GAM28479.1 - 0.1 12.6 1.8 0.58 10.1 0.0 2.5 3 1 0 3 3 3 0 Bacterial epsilon antitoxin Ank PF00023.25 GAM28479.1 - 0.11 12.3 0.3 20 5.2 0.0 3.7 5 0 0 5 5 5 0 Ankyrin repeat GMC_oxred_N PF00732.14 GAM28482.1 - 3.5e-37 128.1 0.0 9.1e-37 126.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 GAM28482.1 - 1.3e-25 90.4 0.5 2.7e-25 89.3 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 GAM28482.1 - 3.4e-06 26.1 0.2 0.00057 18.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 GAM28482.1 - 1.7e-05 24.7 0.2 4.3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 GAM28482.1 - 0.00021 20.3 0.3 0.00077 18.4 0.2 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM28482.1 - 0.00069 18.1 0.1 0.0012 17.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM28482.1 - 0.0013 18.8 0.1 0.11 12.5 0.1 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 GAM28482.1 - 0.0044 16.1 0.2 0.0087 15.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 GAM28482.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM28482.1 - 0.017 15.0 0.2 0.044 13.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 GAM28482.1 - 0.023 13.7 0.1 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 GAM28482.1 - 0.12 11.1 0.1 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2419 PF10343.4 GAM28483.1 - 2.8e-34 118.6 0.0 7.2e-34 117.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) Use1 PF09753.4 GAM28484.1 - 3.1e-23 82.5 10.6 4.9e-23 81.8 7.3 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 YlqD PF11068.3 GAM28484.1 - 0.062 13.3 4.6 2.3 8.2 0.3 2.4 2 0 0 2 2 2 0 YlqD protein TMF_TATA_bd PF12325.3 GAM28484.1 - 2 8.1 13.2 0.58 9.8 0.6 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 GAM28484.1 - 7.9 6.0 7.9 46 3.5 0.0 3.2 3 0 0 3 3 3 0 IncA protein Oligomerisation PF02410.10 GAM28485.1 - 4.3e-21 74.8 0.7 4.3e-21 74.8 0.5 2.2 2 0 0 2 2 2 1 Oligomerisation domain Trypan_PARP PF05887.6 GAM28485.1 - 9.9 5.9 30.5 2.8 7.7 12.6 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SH3_9 PF14604.1 GAM28486.1 - 6.6e-18 64.0 0.3 1.1e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 GAM28486.1 - 5.1e-17 61.8 10.3 1.2e-16 60.6 0.0 3.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 GAM28486.1 - 4.8e-16 57.8 0.1 8.4e-16 57.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 GAM28486.1 - 1.1e-12 47.1 0.0 1.8e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CortBP2 PF09727.4 GAM28486.1 - 0.0017 17.9 2.3 0.0028 17.1 1.6 1.3 1 0 0 1 1 1 1 Cortactin-binding protein-2 MscS_porin PF12795.2 GAM28486.1 - 0.038 13.2 9.8 0.019 14.2 4.8 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Lung_7-TM_R PF06814.8 GAM28487.1 - 2.1e-51 174.6 8.3 3.1e-51 174.0 5.7 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF92 PF01940.11 GAM28487.1 - 0.68 9.0 3.3 0.25 10.4 0.2 1.7 2 0 0 2 2 2 0 Integral membrane protein DUF92 Cyclin PF08613.6 GAM28488.1 - 3.4e-32 111.9 0.3 3.4e-32 111.9 0.2 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 GAM28488.1 - 7e-12 45.0 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3526 PF12040.3 GAM28488.1 - 0.048 13.8 0.2 0.3 11.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3526) Macoilin PF09726.4 GAM28488.1 - 5.3 5.2 9.1 7.7 4.6 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein PIG-H PF10181.4 GAM28489.1 - 3.4e-18 65.0 0.9 3.4e-18 65.0 0.6 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Wzy_C PF04932.10 GAM28489.1 - 0.97 9.1 4.8 1.2 8.8 3.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase Glyco_hydro_38 PF01074.17 GAM28490.1 - 2.7e-86 289.2 0.2 5.7e-86 288.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 GAM28490.1 - 6.2e-24 84.0 0.0 1.5e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38C PF07748.8 GAM28490.1 - 5.6e-15 55.0 0.1 7.7e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain DUF3514 PF12027.3 GAM28490.1 - 0.1 11.7 0.2 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) GPI2 PF06432.6 GAM28491.1 - 8e-91 304.2 19.7 9.7e-91 304.0 13.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Reticulon PF02453.12 GAM28492.1 - 7.5e-07 28.9 14.5 9.9e-07 28.5 10.1 1.2 1 0 0 1 1 1 1 Reticulon YobH PF13996.1 GAM28492.1 - 0.16 11.9 1.2 0.45 10.4 0.8 1.8 1 0 0 1 1 1 0 YobH-like protein MMS22L_C PF14911.1 GAM28493.1 - 0.03 13.4 2.1 1.2 8.0 0.2 2.4 1 1 1 2 2 2 0 S-phase genomic integrity recombination mediator, C-terminal LRR_4 PF12799.2 GAM28494.1 - 5.2 6.8 6.5 3.6 7.3 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 GAM28495.1 - 0.074 12.6 4.1 7.5 6.2 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 GAM28496.1 - 0.0081 15.7 0.9 0.95 9.1 0.0 3.6 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 GAM28497.1 - 0.046 13.3 0.6 0.39 10.3 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Focal_AT PF03623.8 GAM28501.1 - 0.22 11.0 5.5 14 5.1 0.1 3.8 3 0 0 3 3 3 0 Focal adhesion targeting region Dicty_CTDC PF00526.13 GAM28502.1 - 8.9e-235 756.5 926.8 3.5e-10 39.5 8.8 53.7 53 1 0 53 53 53 49 Dictyostelium (slime mold) repeat Glyoxalase_4 PF13669.1 GAM28502.1 - 0.1 12.6 1.7 22 5.0 0.0 4.6 5 1 1 6 6 6 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Prefoldin_3 PF13758.1 GAM28503.1 - 0.045 13.5 3.5 0.053 13.3 2.4 1.3 1 1 0 1 1 1 0 Prefoldin subunit Sugarporin_N PF11471.3 GAM28503.1 - 0.14 11.7 0.2 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pox_A28 PF04584.9 GAM28503.1 - 0.24 11.2 1.4 0.3 10.9 0.6 1.4 1 1 0 1 1 1 0 Poxvirus A28 family DUF445 PF04286.7 GAM28503.1 - 0.84 9.0 3.9 0.89 9.0 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HSP20 PF00011.16 GAM28504.1 - 4.4e-14 52.1 0.0 2.6e-08 33.6 0.0 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.11 GAM28504.1 - 0.0077 16.7 0.3 0.26 11.8 0.1 2.4 2 0 0 2 2 2 1 CS domain PPO1_KFDV PF12143.3 GAM28504.1 - 0.042 13.7 0.2 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) DUF320 PF03777.8 GAM28504.1 - 0.25 11.1 2.2 0.5 10.1 1.5 1.4 1 0 0 1 1 1 0 Small secreted domain (DUF320) Dicty_CTDC PF00526.13 GAM28505.1 - 4.1e-137 444.7 547.8 2.4e-08 33.6 7.7 36.7 34 5 1 35 35 35 31 Dictyostelium (slime mold) repeat DUF1469 PF07332.6 GAM28506.1 - 0.51 10.0 5.6 0.15 11.7 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Herpes_US9 PF06072.6 GAM28506.1 - 1.2 9.0 5.9 0.33 10.8 0.8 2.6 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 Voltage_CLC PF00654.15 GAM28506.1 - 1.8 7.4 15.7 0.03 13.3 5.1 1.8 1 1 1 2 2 2 0 Voltage gated chloride channel 7TMR-DISM_7TM PF07695.6 GAM28506.1 - 2.4 7.7 28.7 0.0094 15.6 11.4 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling NDT80_PhoG PF05224.7 GAM28507.1 - 3.8e-16 59.6 0.0 3.8e-16 59.6 0.0 5.0 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 GAM28507.1 - 1.2e-12 47.7 0.2 3.1e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase LMBR1 PF04791.11 GAM28507.1 - 0.0041 15.7 0.0 0.02 13.5 0.0 2.0 2 1 0 2 2 2 1 LMBR1-like membrane protein MRF_C1 PF13887.1 GAM28507.1 - 0.3 10.1 0.0 0.58 9.2 0.0 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Zn_dep_PLPC PF00882.13 GAM28508.1 - 0.014 15.0 0.2 0.018 14.7 0.2 1.2 1 0 0 1 1 1 0 Zinc dependent phospholipase C Zn_dep_PLPC PF00882.13 GAM28509.1 - 0.047 13.3 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Zinc dependent phospholipase C Nckap1 PF09735.4 GAM28510.1 - 2.7e-194 647.7 4.6 3.2e-194 647.5 3.2 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein EF-hand_1 PF00036.27 GAM28511.1 - 3.9e-15 53.9 0.1 3.1e-06 26.0 0.0 2.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 GAM28511.1 - 2.9e-13 49.7 0.0 4.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 GAM28511.1 - 9.4e-13 47.5 0.0 7.4e-11 41.5 0.0 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 GAM28511.1 - 1.2e-12 46.5 0.0 5.5e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 GAM28511.1 - 1.2e-08 33.9 0.8 0.0002 20.5 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 GAM28511.1 - 7e-05 22.6 0.0 9.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.2 GAM28511.1 - 0.0053 16.4 0.0 0.0066 16.1 0.0 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 GAM28511.1 - 0.0068 16.4 0.0 0.0076 16.2 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 GAM28511.1 - 0.0082 15.7 0.0 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 EF hand Beta-lactamase2 PF13354.1 GAM28511.1 - 0.01 15.2 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 0 Beta-lactamase enzyme family EF-hand_like PF09279.6 GAM28511.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like UPF0154 PF03672.8 GAM28511.1 - 0.082 12.5 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Complex1_LYR_1 PF13232.1 GAM28512.1 - 0.0014 18.7 0.4 0.0019 18.3 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 GAM28512.1 - 0.0037 17.0 0.4 0.0052 16.5 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) FNIP PF05725.7 GAM28513.1 - 2.3e-86 283.5 22.1 2.5e-15 56.1 0.0 10.1 10 1 1 11 11 11 10 FNIP Repeat ADH_zinc_N PF00107.21 GAM28514.1 - 3.9e-17 62.0 0.1 7.2e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 GAM28514.1 - 5e-13 48.7 0.0 9.7e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 GAM28514.1 - 0.067 13.1 0.8 0.39 10.7 0.5 2.1 2 0 0 2 2 2 0 TrkA-N domain SPG48 PF14764.1 GAM28515.1 - 2.5e-95 319.6 2.6 2.5e-95 319.6 1.8 1.6 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking F-box PF00646.28 GAM28516.1 - 0.054 13.1 0.8 0.22 11.2 0.6 2.0 1 1 0 1 1 1 0 F-box domain Sdh5 PF03937.11 GAM28519.1 - 5.2e-24 83.7 0.6 7.1e-24 83.3 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF2348 PF09807.4 GAM28520.1 - 1.3e-28 99.7 0.3 5.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 GAM28520.1 - 3.7e-05 23.2 0.0 0.00075 18.9 0.0 2.1 2 0 0 2 2 2 1 Elongator subunit Iki1 Ras PF00071.17 GAM28521.1 - 3.7e-51 172.7 0.0 4.6e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28521.1 - 7e-15 55.5 0.0 1.4e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28521.1 - 1.4e-07 30.9 0.1 3.9e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM28521.1 - 0.0043 16.5 0.1 0.22 10.9 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM28521.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 GAM28521.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FAD_binding_1 PF00667.15 GAM28522.1 - 3.9e-41 140.8 0.4 7.9e-41 139.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 GAM28522.1 - 3.5e-28 98.4 0.1 1.2e-27 96.6 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 GAM28522.1 - 5.4e-22 78.4 0.0 1.3e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 GAM28522.1 - 0.0023 17.9 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 GAM28522.1 - 0.0028 17.5 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Glyco_hydro_16 PF00722.16 GAM28523.1 - 5.5e-28 97.5 0.4 7e-28 97.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 GAM28523.1 - 3.7e-05 22.0 6.3 0.00036 18.8 1.9 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Ank_5 PF13857.1 GAM28525.1 - 8.1e-07 29.0 0.8 0.2 11.9 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM28525.1 - 1.5e-06 28.4 0.0 0.00027 21.2 0.0 2.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM28525.1 - 6.8e-06 25.8 0.1 2.4 8.6 0.1 4.4 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.25 GAM28525.1 - 6.1e-05 22.6 0.1 2.1 8.3 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 GAM28525.1 - 0.00057 20.3 0.9 2.9 8.5 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) RRS1 PF04939.7 GAM28526.1 - 5.3e-45 152.8 4.8 5.3e-45 152.8 3.3 1.7 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) PPARgamma_N PF12577.3 GAM28526.1 - 0.093 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 PPAR gamma N-terminal region RRM_1 PF00076.17 GAM28527.1 - 8.4e-39 131.0 0.0 1.5e-18 66.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28527.1 - 6.5e-21 74.0 0.0 1.4e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM28527.1 - 1.1e-18 66.7 0.0 9.6e-09 34.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 GAM28527.1 - 0.0046 16.7 3.0 1.8 8.4 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.6 GAM28527.1 - 0.019 14.9 0.0 0.71 9.8 0.0 2.6 2 0 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 GAM28527.1 - 0.11 12.2 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 GAM28528.1 - 2.6e-17 62.2 0.1 3.8e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28528.1 - 4.7e-11 42.5 0.1 7.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM28528.1 - 2.3e-09 36.9 0.1 3.3e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-gamma PF00631.17 GAM28529.1 - 3.4e-16 58.7 0.2 4.1e-16 58.4 0.1 1.0 1 0 0 1 1 1 1 GGL domain F_actin_bind PF08919.5 GAM28529.1 - 0.036 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 F-actin binding Peptidase_S28 PF05577.7 GAM28530.1 - 3e-128 428.1 2.1 3.5e-128 427.8 1.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 GAM28530.1 - 1.9e-07 29.9 0.3 2.9e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.15 GAM28530.1 - 0.00025 20.6 0.0 0.00052 19.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 GAM28530.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM28530.1 - 0.0039 16.4 0.0 0.0071 15.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Dicty_CTDC PF00526.13 GAM28531.1 - 2.6e-146 474.0 410.6 2.3e-10 40.1 5.9 27.5 27 0 0 27 27 27 26 Dictyostelium (slime mold) repeat SGS PF05002.10 GAM28532.1 - 6.5e-24 83.5 0.3 1.7e-23 82.1 0.2 1.7 1 0 0 1 1 1 1 SGS domain TPR_11 PF13414.1 GAM28532.1 - 5.8e-18 64.3 0.6 1.2e-10 40.8 0.2 2.2 2 0 0 2 2 2 2 TPR repeat CS PF04969.11 GAM28532.1 - 5.6e-17 62.0 1.1 9.7e-17 61.2 0.3 1.8 2 0 0 2 2 2 1 CS domain TPR_1 PF00515.23 GAM28532.1 - 5.5e-15 54.2 1.9 0.00035 20.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM28532.1 - 1.6e-13 49.4 0.2 0.0022 17.7 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM28532.1 - 3.4e-08 33.5 2.3 6.5e-08 32.6 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 GAM28532.1 - 4.2e-07 29.6 0.2 0.0087 16.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM28532.1 - 2.7e-05 24.0 0.0 0.004 17.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM28532.1 - 8.1e-05 22.1 0.5 0.023 14.4 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 GAM28532.1 - 0.00046 19.9 0.0 0.0069 16.2 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM28532.1 - 0.00088 19.7 0.0 0.1 13.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM28532.1 - 0.0025 18.4 0.0 0.12 13.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 GAM28532.1 - 0.0032 17.3 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 GAM28532.1 - 0.0072 16.6 0.0 4.8 7.5 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM28532.1 - 0.018 14.7 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 GAM28532.1 - 0.045 13.6 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF2360 PF10152.4 GAM28532.1 - 1.3 9.3 6.5 3.2 8.0 4.5 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Med3 PF11593.3 GAM28532.1 - 8.1 5.5 10.1 12 5.0 7.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GHMP_kinases_N PF00288.21 GAM28533.1 - 5e-05 23.2 0.5 0.00022 21.2 0.4 2.2 1 0 0 1 1 1 1 GHMP kinases N terminal domain ATP-grasp_3 PF02655.9 GAM28533.1 - 0.084 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Ribosomal_L16 PF00252.13 GAM28535.1 - 1e-32 112.7 0.0 1.4e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CN_hydrolase PF00795.17 GAM28536.1 - 1.7e-34 118.7 0.0 2.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_6 PF13964.1 GAM28537.1 - 1.4e-11 43.9 10.1 2.5e-05 24.2 0.0 5.5 3 1 2 5 5 5 3 Kelch motif Kelch_1 PF01344.20 GAM28537.1 - 2.4e-11 42.9 8.3 0.019 14.5 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 GAM28537.1 - 2e-08 33.8 15.6 0.17 11.6 0.1 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM28537.1 - 1.2e-07 31.4 13.4 0.057 13.4 0.8 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 GAM28537.1 - 0.00019 21.0 4.9 1.7 8.5 0.0 4.6 4 0 0 4 4 4 2 Kelch motif ArsC PF03960.10 GAM28537.1 - 0.11 12.5 0.4 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 ArsC family NAD_binding_6 PF08030.7 GAM28538.1 - 1.6e-34 119.0 0.0 2.3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 GAM28538.1 - 1.8e-19 69.5 0.1 9e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 GAM28538.1 - 2.9e-17 62.9 11.3 3.1e-17 62.8 5.0 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 GAM28538.1 - 2.4e-05 24.3 0.0 5.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 GAM28538.1 - 0.0026 18.3 0.0 5 7.7 0.0 2.6 2 1 0 2 2 2 2 Oxidoreductase NAD-binding domain Allexi_40kDa PF05549.6 GAM28538.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein HCNGP PF07818.8 GAM28541.1 - 2.7e-28 97.8 3.4 2.7e-28 97.8 2.3 2.2 2 0 0 2 2 2 1 HCNGP-like protein Mucin PF01456.12 GAM28541.1 - 9.3 6.0 18.6 2.1 8.0 2.8 2.8 3 0 0 3 3 3 0 Mucin-like glycoprotein MitMem_reg PF13012.1 GAM28542.1 - 9e-31 106.3 1.7 4.8e-30 103.9 1.2 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 GAM28542.1 - 8.3e-27 93.1 0.0 2.2e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2999 PF11212.3 GAM28542.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) PTPLA PF04387.9 GAM28543.1 - 6.2e-46 155.8 10.1 8.5e-46 155.3 7.0 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2842 PF11003.3 GAM28543.1 - 2.2 8.2 8.4 0.19 11.6 1.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2842) RRM_1 PF00076.17 GAM28544.1 - 2.6e-47 158.3 0.5 1.1e-18 66.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28544.1 - 1.7e-39 133.6 0.2 4.2e-15 55.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM28544.1 - 2e-33 114.0 1.2 5.8e-12 45.2 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 GAM28544.1 - 4.5e-11 41.9 0.0 1.6e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 GAM28544.1 - 0.035 13.6 0.2 0.093 12.2 0.2 1.7 1 0 0 1 1 1 0 HeH/LEM domain HEAT PF02985.17 GAM28545.1 - 1.3e-13 49.7 2.5 0.017 15.1 0.0 8.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 GAM28545.1 - 2.4e-08 34.1 0.0 1.5 9.1 0.0 6.7 5 1 1 6 6 6 2 HEAT repeats B56 PF01603.15 GAM28545.1 - 0.00015 20.4 7.6 0.0099 14.5 0.0 4.0 4 0 0 4 4 4 2 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT_EZ PF13513.1 GAM28545.1 - 0.0015 18.9 0.0 43 4.7 0.0 6.3 7 0 0 7 7 7 0 HEAT-like repeat Cohesin_HEAT PF12765.2 GAM28545.1 - 0.007 16.3 3.3 6.4 6.8 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Aldedh PF00171.17 GAM28545.1 - 0.23 9.7 0.0 0.4 8.9 0.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family UCH PF00443.24 GAM28546.1 - 2.4e-49 167.8 3.3 2.4e-49 167.8 2.3 3.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM28546.1 - 1.6e-27 96.7 0.7 4.7e-27 95.1 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 GAM28546.1 - 0.0025 17.1 0.1 0.0066 15.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF726 PF05277.7 GAM28547.1 - 5.7e-60 203.0 3.6 7.1e-56 189.5 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) VPS9 PF02204.13 GAM28547.1 - 4.6e-15 55.5 0.1 2.2e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RICTOR_M PF14666.1 GAM28547.1 - 0.018 14.0 1.4 0.54 9.2 0.2 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain zf-met2 PF12907.2 GAM28548.1 - 1.6e-16 59.9 3.0 2.2e-16 59.5 2.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 GAM28548.1 - 8.4e-07 29.6 11.1 8.4e-07 29.6 7.7 1.6 2 0 0 2 2 2 1 4F5 protein family Rpr2 PF04032.11 GAM28548.1 - 0.025 14.4 0.8 0.028 14.3 0.6 1.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_4 PF13894.1 GAM28548.1 - 0.15 12.4 1.2 0.26 11.7 0.8 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger STT3 PF02516.9 GAM28549.1 - 1e-119 400.7 42.5 3e-119 399.1 29.5 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DER1 PF04511.10 GAM28550.1 - 1.3e-54 184.7 18.5 1.5e-54 184.5 12.8 1.0 1 0 0 1 1 1 1 Der1-like family RAI16-like PF10257.4 GAM28552.1 - 8.5e-78 261.7 3.0 8.5e-78 261.7 2.1 1.5 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein LIM PF00412.17 GAM28553.1 - 5.1e-12 45.6 7.5 7.2e-12 45.1 5.2 1.2 1 0 0 1 1 1 1 LIM domain DUF4428 PF14471.1 GAM28553.1 - 0.54 10.0 3.6 0.6 9.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) C1_1 PF00130.17 GAM28553.1 - 0.82 9.4 7.8 0.71 9.6 1.8 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Synaptobrevin PF00957.16 GAM28554.1 - 5e-13 48.4 1.6 9.6e-13 47.5 1.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 GAM28554.1 - 2.4e-07 30.2 0.0 3.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain GED PF02212.13 GAM28554.1 - 0.087 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Dynamin GTPase effector domain Ank_2 PF12796.2 GAM28555.1 - 9.2e-37 125.2 15.3 2.3e-10 40.6 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28555.1 - 1.7e-21 76.1 8.4 1.8e-05 25.1 0.0 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28555.1 - 2.6e-21 75.1 10.9 0.00042 20.4 0.2 8.6 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28555.1 - 4e-16 57.5 6.6 0.14 12.4 0.0 9.4 8 2 2 10 10 10 4 Ankyrin repeat Ank PF00023.25 GAM28555.1 - 1.5e-13 49.7 8.8 0.031 14.0 0.1 9.1 8 1 1 9 9 9 4 Ankyrin repeat DUF2493 PF10686.4 GAM28555.1 - 0.073 12.6 0.1 12 5.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2493) ThiF PF00899.16 GAM28558.1 - 2.8e-15 56.3 0.3 1.2e-14 54.2 0.1 1.9 2 0 0 2 2 2 1 ThiF family NAD_binding_7 PF13241.1 GAM28558.1 - 0.0083 16.3 0.5 0.033 14.4 0.0 2.0 2 1 0 2 2 2 1 Putative NAD(P)-binding Pkinase PF00069.20 GAM28559.1 - 3.5e-19 68.9 3.6 9.3e-17 61.0 2.5 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28559.1 - 6.2e-15 54.9 0.0 3.6e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1084 PF06454.6 GAM28559.1 - 0.93 8.4 8.4 0.04 12.9 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1084) tRNA-synt_1 PF00133.17 GAM28560.1 - 1.1e-56 192.1 6.5 2.9e-32 111.4 4.7 6.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 GAM28560.1 - 4.4e-31 107.6 0.0 8.3e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 GAM28560.1 - 2.1e-30 105.6 0.0 9.4e-23 80.4 0.0 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 GAM28560.1 - 8.7e-12 45.0 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 GAM28560.1 - 1.4e-05 24.3 0.1 0.053 12.6 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 GAM28560.1 - 0.0035 16.2 0.0 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 GAM28560.1 - 0.0079 14.9 0.0 0.34 9.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (K) DNA_ligase_ZBD PF03119.11 GAM28560.1 - 0.11 12.1 2.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.5 GAM28560.1 - 0.26 11.2 1.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Alpha-amylase PF00128.19 GAM28561.1 - 8.2e-76 255.4 0.0 1.6e-75 254.4 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 GAM28561.1 - 0.0048 14.7 0.3 0.096 10.4 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 CH PF00307.26 GAM28562.1 - 5.1e-15 55.4 0.2 9.4e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM28562.1 - 0.00067 19.2 0.2 0.0024 17.4 0.1 1.9 1 0 0 1 1 1 1 CAMSAP CH domain Rotamase_3 PF13616.1 GAM28563.1 - 4.3e-20 72.1 0.0 5.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 GAM28563.1 - 1.7e-19 70.3 0.0 2.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 GAM28563.1 - 3.4e-07 30.8 0.0 4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain RhoGEF PF00621.15 GAM28564.1 - 3.9e-32 111.5 6.3 5.5e-32 111.0 4.4 1.2 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.22 GAM28564.1 - 2.3e-05 23.6 0.3 5.2e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif HEAT PF02985.17 GAM28565.1 - 1.2e-09 37.4 3.1 0.15 12.2 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 GAM28565.1 - 0.00011 22.4 0.0 0.79 10.0 0.0 5.6 5 1 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.1 GAM28565.1 - 0.02 15.3 0.0 11 6.6 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat FAD_binding_3 PF01494.14 GAM28566.1 - 1.7e-21 76.6 0.1 7.5e-12 44.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 GAM28566.1 - 7.4e-07 28.2 0.1 1.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 GAM28566.1 - 9.7e-07 27.7 0.0 0.0064 15.1 0.0 3.3 3 1 1 4 4 4 2 Tryptophan halogenase DAO PF01266.19 GAM28566.1 - 1.2e-05 24.3 0.1 0.0034 16.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 GAM28566.1 - 1.3e-05 24.3 0.1 0.0094 14.9 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 GAM28566.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF447 PF04289.7 GAM28566.1 - 0.014 14.9 0.1 0.03 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Thi4 PF01946.12 GAM28566.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 GAM28566.1 - 0.049 13.6 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Rubella_E1 PF05748.6 GAM28566.1 - 0.053 12.1 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 NAD_binding_9 PF13454.1 GAM28566.1 - 0.097 12.4 0.1 0.68 9.6 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 GAM28566.1 - 0.11 12.9 0.4 0.28 11.5 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 GAM28567.1 - 2.7e-25 87.2 15.3 2.2e-06 27.3 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Methyltransf_11 PF08241.7 GAM28568.1 - 2.4e-23 82.4 0.1 9.2e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM28568.1 - 2.4e-19 69.3 0.0 5.8e-19 68.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM28568.1 - 4.1e-19 68.8 0.0 6.3e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM28568.1 - 1.8e-16 59.9 0.0 4.2e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 GAM28568.1 - 3.1e-13 50.2 0.0 9.7e-13 48.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM28568.1 - 2.4e-12 47.1 0.0 3.1e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM28568.1 - 4.3e-12 46.2 0.0 1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM28568.1 - 5.4e-11 42.5 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 GAM28568.1 - 1.7e-09 37.1 0.0 3.9e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 GAM28568.1 - 0.00023 20.5 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Polyketide_cyc2 PF10604.4 GAM28568.1 - 0.0003 20.9 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_8 PF05148.10 GAM28568.1 - 0.00033 20.3 0.1 0.0018 17.9 0.0 2.1 2 1 1 3 3 3 1 Hypothetical methyltransferase Methyltransf_15 PF09445.5 GAM28568.1 - 0.00045 19.8 0.1 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 GAM28568.1 - 0.00058 19.2 0.0 0.0016 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 GAM28568.1 - 0.004 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 COXG PF06240.8 GAM28568.1 - 0.0093 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) DOT1 PF08123.8 GAM28568.1 - 0.018 14.3 0.2 0.06 12.6 0.0 1.9 2 0 0 2 2 2 0 Histone methylation protein DOT1 TehB PF03848.9 GAM28568.1 - 0.057 12.5 0.1 0.24 10.5 0.0 2.1 3 0 0 3 3 3 0 Tellurite resistance protein TehB DNA_ligase_OB PF03120.11 GAM28568.1 - 0.084 12.5 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Methyltransf_32 PF13679.1 GAM28568.1 - 0.095 12.3 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain RVT_N PF13655.1 GAM28568.1 - 0.19 11.7 2.5 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase Abhydrolase_5 PF12695.2 GAM28569.1 - 3e-13 49.7 0.0 4.8e-13 49.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 GAM28569.1 - 5.1e-11 42.5 0.0 7.9e-11 41.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 GAM28569.1 - 9.2e-11 41.1 0.1 2.3e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 GAM28569.1 - 2.4e-06 26.9 0.0 0.00089 18.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 GAM28569.1 - 5.8e-05 21.5 0.1 0.00031 19.1 0.0 1.9 1 1 1 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 GAM28569.1 - 6.4e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 GAM28569.1 - 8.3e-05 21.5 0.1 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 GAM28569.1 - 0.00056 19.4 0.0 0.91 8.9 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2424 PF10340.4 GAM28569.1 - 0.00071 18.3 0.1 0.001 17.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF915 PF06028.6 GAM28569.1 - 0.0088 15.1 0.1 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 GAM28569.1 - 0.025 14.0 1.2 0.091 12.1 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) Ank_2 PF12796.2 GAM28570.1 - 2.5e-13 50.1 0.3 6.2e-09 36.0 0.4 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28570.1 - 4.8e-11 42.8 8.7 0.0005 20.5 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28570.1 - 2.6e-09 36.3 5.5 1.3 9.4 0.0 5.8 5 1 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 GAM28570.1 - 2.3e-08 33.9 1.0 0.25 11.6 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM28570.1 - 1e-07 31.3 0.4 2.1 8.3 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat WRC PF08879.5 GAM28571.1 - 0.0059 16.2 4.4 0.0059 16.2 3.0 2.5 1 1 1 2 2 2 1 WRC DUF1936 PF09151.5 GAM28571.1 - 0.45 10.0 2.6 11 5.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Peptidase_C48 PF02902.14 GAM28572.1 - 3.8e-09 36.5 0.2 9.3e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Alpha_L_fucos PF01120.12 GAM28572.1 - 0.052 12.4 1.3 0.074 11.9 0.5 1.5 1 1 1 2 2 2 0 Alpha-L-fucosidase LUC7 PF03194.10 GAM28573.1 - 2.5 7.5 17.2 1.1 8.6 9.5 1.9 2 0 0 2 2 2 0 LUC7 N_terminus HSDR_N_2 PF13588.1 GAM28574.1 - 0.016 14.9 0.2 0.024 14.4 0.1 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DAG1 PF05454.6 GAM28574.1 - 0.024 13.8 0.9 0.028 13.5 0.6 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Cir_N PF10197.4 GAM28574.1 - 0.093 12.7 1.8 0.25 11.4 0.8 2.1 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF4200 PF13863.1 GAM28574.1 - 0.13 12.2 1.5 0.19 11.6 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Mg296 PF09644.5 GAM28574.1 - 0.13 12.0 0.8 0.2 11.5 0.5 1.4 1 1 0 1 1 1 0 Mg296 protein EAP30 PF04157.11 GAM28578.1 - 2.9e-51 173.7 2.8 2.9e-51 173.7 2.0 2.1 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 GAM28578.1 - 2.8e-15 55.8 0.0 2.2e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 RPW8 PF05659.6 GAM28578.1 - 0.0044 16.5 0.3 0.0089 15.5 0.2 1.6 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 SYF2 PF08231.7 GAM28578.1 - 0.067 13.3 5.6 0.12 12.4 3.9 1.5 1 0 0 1 1 1 0 SYF2 splicing factor DUF1635 PF07795.6 GAM28578.1 - 0.53 9.6 8.7 0.18 11.1 3.7 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) TSA PF03249.8 GAM28578.1 - 0.8 8.1 11.8 1.2 7.5 8.1 1.2 1 0 0 1 1 1 0 Type specific antigen APC_CDC26 PF10471.4 GAM28578.1 - 5.6 7.7 12.7 15 6.4 8.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 WD40 PF00400.27 GAM28579.1 - 5.3e-06 26.1 1.9 0.34 10.8 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Synaptobrevin PF00957.16 GAM28579.1 - 1.7e-05 24.3 2.2 3e-05 23.5 1.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Tfb4 PF03850.9 GAM28580.1 - 2.9e-83 279.3 3.9 4.3e-83 278.7 2.7 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-AN1 PF01428.11 GAM28580.1 - 8.3 6.3 9.9 7.4 6.5 3.4 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger ACPS PF01648.15 GAM28581.1 - 1.3e-26 92.7 0.0 1.5e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RCC1 PF00415.13 GAM28582.1 - 9.1e-79 259.5 17.4 1.5e-15 57.1 0.6 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.14 GAM28582.1 - 3e-44 151.0 0.0 3e-44 151.0 0.0 3.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RCC1_2 PF13540.1 GAM28582.1 - 2.1e-42 141.8 30.8 1.1e-08 34.3 0.1 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.15 GAM28582.1 - 1.3e-22 80.5 2.0 1.3e-22 80.5 1.4 3.0 3 0 0 3 3 3 1 RhoGEF domain CAF-1_p150 PF11600.3 GAM28582.1 - 0.00025 20.4 30.9 0.00025 20.4 21.4 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal OppC_N PF12911.2 GAM28582.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C EB PF01683.13 GAM28583.1 - 0.0017 18.3 77.8 0.0062 16.5 5.5 7.7 4 1 2 6 6 6 4 EB module Lustrin_cystein PF14625.1 GAM28583.1 - 0.018 15.1 0.5 0.018 15.1 0.4 7.9 6 1 1 7 7 7 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.7 GAM28583.1 - 1.6 8.9 67.1 0.17 12.0 1.5 6.6 3 2 2 6 6 6 0 Dickkopf N-terminal cysteine-rich region LRR_4 PF12799.2 GAM28584.1 - 2.1e-09 36.8 35.3 0.0043 16.6 2.0 7.3 5 2 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM28584.1 - 3e-07 29.5 35.1 0.17 12.0 0.1 10.0 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.1 GAM28584.1 - 1.9e-06 27.3 52.4 0.22 11.6 0.1 11.6 12 0 0 12 12 12 5 Leucine Rich repeat LRR_8 PF13855.1 GAM28584.1 - 0.016 14.9 41.7 0.12 12.1 3.8 6.9 4 2 4 8 8 8 0 Leucine rich repeat LRR_7 PF13504.1 GAM28584.1 - 0.066 13.4 38.3 1.5 9.3 0.1 10.5 11 0 0 11 11 11 0 Leucine rich repeat BAF1_ABF1 PF04684.8 GAM28584.1 - 7.9 5.1 13.4 1.3 7.7 6.7 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Ras PF00071.17 GAM28585.1 - 3e-53 179.5 0.1 3.5e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM28585.1 - 2.8e-18 66.5 0.0 4.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 GAM28585.1 - 3.9e-10 39.2 0.2 4.7e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 GAM28585.1 - 7.5e-05 22.2 0.3 0.00018 20.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM28585.1 - 0.00047 20.0 0.0 0.00061 19.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hist_deacetyl PF00850.14 GAM28586.1 - 7e-79 265.3 0.0 9.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Patched PF02460.13 GAM28587.1 - 8e-84 282.0 21.6 1.5e-83 281.1 13.5 2.4 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.3 GAM28587.1 - 5.1e-48 162.4 7.5 5.1e-48 162.4 5.2 3.4 3 1 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 GAM28587.1 - 0.06 10.7 20.0 0.11 9.8 13.9 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2215 PF10225.4 GAM28588.1 - 5 6.5 11.1 8.8 5.6 7.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF155 PF02582.9 GAM28589.1 - 2.7e-37 128.3 1.9 7.8e-37 126.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Pex14_N PF04695.8 GAM28589.1 - 1.6 8.8 10.9 2.7 8.0 7.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YL1 PF05764.8 GAM28590.1 - 0.00067 19.3 9.1 0.00089 18.9 6.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein PAT1 PF09770.4 GAM28590.1 - 7.1 4.7 29.4 8.7 4.4 20.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCM PF00493.18 GAM28591.1 - 7e-136 452.3 0.2 1.2e-135 451.5 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 GAM28591.1 - 1.3e-15 57.9 1.9 7.6e-15 55.4 1.3 2.4 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 GAM28591.1 - 3.4e-08 32.8 0.0 2e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 GAM28591.1 - 9.7e-05 21.9 0.0 0.00057 19.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM28591.1 - 0.00021 21.0 0.0 0.00052 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 GAM28591.1 - 0.0032 16.9 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain RXT2_N PF08595.6 GAM28591.1 - 1.5 8.6 8.5 3.3 7.5 5.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 GAM28591.1 - 1.6 8.2 8.5 3.1 7.2 5.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 GAM28591.1 - 2.5 8.4 12.5 6.6 7.1 8.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 GAM28591.1 - 5.6 5.5 11.8 9.7 4.7 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 GAM28591.1 - 6.8 6.9 12.0 15 5.9 8.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Filamin PF00630.14 GAM28593.1 - 2e-110 362.1 9.0 2.4e-22 79.4 0.1 6.2 5 1 1 6 6 6 6 Filamin/ABP280 repeat CH PF00307.26 GAM28593.1 - 1.3e-31 108.7 0.1 4.7e-16 58.7 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Big_1 PF02369.11 GAM28593.1 - 1.2e-10 41.1 7.2 0.047 13.6 0.0 6.1 5 1 1 6 6 6 2 Bacterial Ig-like domain (group 1) CAMSAP_CH PF11971.3 GAM28593.1 - 3.5e-05 23.3 0.0 0.0096 15.5 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain Y_Y_Y PF07495.8 GAM28593.1 - 5e-05 22.9 0.8 0.32 10.7 0.0 4.8 5 0 0 5 5 5 1 Y_Y_Y domain Neurexophilin PF06312.7 GAM28593.1 - 0.00058 19.1 0.4 2.3 7.4 0.0 4.2 5 0 0 5 5 5 1 Neurexophilin YtkA PF13115.1 GAM28593.1 - 0.0016 18.7 4.0 0.93 9.8 0.0 4.5 4 1 1 5 5 5 1 YtkA-like Big_3_4 PF13754.1 GAM28593.1 - 0.022 15.0 18.1 0.14 12.4 0.5 6.3 6 1 1 7 7 7 0 Bacterial Ig-like domain (group 3) Big_3 PF07523.7 GAM28593.1 - 0.44 10.6 10.6 4.1 7.5 0.1 4.7 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF810 PF05664.6 GAM28594.1 - 4.9e-11 41.6 0.7 8.5e-11 40.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF810) Phosphodiest PF01663.17 GAM28594.1 - 0.037 13.3 0.0 0.087 12.1 0.0 1.5 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Homeobox PF00046.24 GAM28596.1 - 0.0011 18.5 1.5 0.0011 18.5 1.0 2.1 2 0 0 2 2 2 1 Homeobox domain Arm PF00514.18 GAM28597.1 - 4e-19 67.6 3.4 0.00059 19.5 0.0 5.9 5 1 1 6 6 6 5 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 GAM28597.1 - 4.2e-08 32.6 2.0 2.6e-05 23.4 0.0 2.8 1 1 0 2 2 2 2 Armadillo-like Atx10homo_assoc PF09759.4 GAM28597.1 - 3.8e-07 29.7 5.9 0.0074 16.0 0.1 4.0 2 1 4 6 6 6 4 Spinocerebellar ataxia type 10 protein domain SoxZ PF08770.6 GAM28597.1 - 0.064 12.6 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Sulphur oxidation protein SoxZ Arm PF00514.18 GAM28598.1 - 0.0001 21.9 0.0 0.0006 19.5 0.0 2.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat F-box-like PF12937.2 GAM28598.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 GAM28598.1 - 0.042 13.5 0.1 0.042 13.5 0.0 2.3 3 0 0 3 3 3 0 F-box domain KASH PF10541.4 GAM28599.1 - 0.098 12.5 8.7 0.13 12.1 6.0 1.1 1 0 0 1 1 1 0 Nuclear envelope localisation domain SKN1 PF03935.10 GAM28599.1 - 0.11 10.6 0.2 0.12 10.5 0.1 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) DUF515 PF04415.7 GAM28600.1 - 0.35 9.0 9.3 0.63 8.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AFT PF08731.6 GAM28601.1 - 0.16 12.1 3.4 0.29 11.3 2.3 1.4 1 0 0 1 1 1 0 Transcription factor AFT DUF4286 PF14114.1 GAM28602.1 - 5.4e-20 71.4 0.0 7.2e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) DEAD PF00270.24 GAM28603.1 - 8e-44 149.0 0.0 5.3e-42 143.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM28603.1 - 6.8e-21 73.9 1.0 1.5e-20 72.8 0.7 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM28603.1 - 0.0005 18.9 0.0 0.0012 17.6 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 GAM28603.1 - 0.0016 18.3 0.0 0.0063 16.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 GAM28603.1 - 0.042 12.8 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Methyltransf_12 PF08242.7 GAM28605.1 - 1.1e-13 51.5 0.3 9.9e-13 48.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM28605.1 - 4.9e-12 45.8 0.3 9.9e-12 44.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM28605.1 - 3.4e-11 43.7 0.0 7.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM28605.1 - 4.2e-09 36.1 0.2 8.5e-09 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM28605.1 - 2.1e-08 34.5 0.1 1.1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM28605.1 - 2.2e-06 27.9 0.0 6.5e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM28605.1 - 6.9e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM28605.1 - 9e-06 25.1 0.0 2.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 GAM28605.1 - 0.0072 15.3 0.1 0.024 13.6 0.0 1.9 2 1 0 2 2 2 1 Putative methyltransferase CheR PF01739.13 GAM28605.1 - 0.035 13.3 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.4 GAM28605.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase FmrO PF07091.6 GAM28605.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Coiled PF05710.7 GAM28607.1 - 0.0002 21.7 13.7 0.00027 21.3 9.5 1.1 1 0 0 1 1 1 1 Coiled coil TcpA PF05946.7 GAM28608.1 - 0.069 13.0 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA MIF4G PF02854.14 GAM28609.1 - 2.5e-22 79.3 10.7 2.5e-22 79.3 7.4 2.3 2 0 0 2 2 2 1 MIF4G domain MCRS_N PF13325.1 GAM28610.1 - 1.6e-11 44.0 0.0 1.6e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of micro-spherule protein Phospholip_B PF04916.8 GAM28611.1 - 1.3e-135 452.6 4.4 1.5e-135 452.4 3.1 1.0 1 0 0 1 1 1 1 Phospholipase B PetM PF08041.6 GAM28612.1 - 0.082 12.3 2.7 0.69 9.4 0.0 2.9 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 VIT1 PF01988.14 GAM28612.1 - 3.4 7.1 6.1 1.2 8.5 0.7 2.4 2 1 0 2 2 2 0 VIT family RhoGAP PF00620.22 GAM28613.1 - 2e-33 115.1 0.7 5.7e-33 113.6 0.1 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 GAM28613.1 - 1.1e-22 80.1 2.0 1.1e-18 67.2 0.0 3.2 3 0 0 3 3 3 2 PH domain F-box-like PF12937.2 GAM28613.1 - 3e-09 36.4 1.0 6.5e-09 35.3 0.7 1.6 1 0 0 1 1 1 1 F-box-like PH_11 PF15413.1 GAM28613.1 - 5e-09 36.4 1.6 0.00013 22.1 0.1 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain F-box PF00646.28 GAM28613.1 - 1.7e-06 27.5 0.3 5.1e-06 25.9 0.2 1.9 1 0 0 1 1 1 1 F-box domain PH_3 PF14593.1 GAM28613.1 - 0.008 16.0 0.8 0.047 13.5 0.0 2.7 3 1 0 3 3 3 1 PH domain PH_8 PF15409.1 GAM28613.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.9 4 0 0 4 4 4 0 Pleckstrin homology domain Gryzun PF07919.7 GAM28614.1 - 1.1e-61 208.8 9.6 1.1e-61 208.8 6.6 2.0 2 1 0 2 2 2 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 GAM28614.1 - 1.5e-44 152.3 9.1 2e-44 151.9 3.4 2.5 2 1 0 2 2 2 1 Foie gras liver health family 1 TPR_1 PF00515.23 GAM28614.1 - 0.0012 18.3 2.3 0.052 13.1 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM28614.1 - 0.0075 16.1 1.8 0.42 10.6 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 GAM28614.1 - 0.0087 15.6 0.6 0.19 11.3 0.2 2.7 2 0 0 2 2 2 1 TPR repeat Gryzun-like PF12742.2 GAM28614.1 - 0.016 14.9 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 Gryzun, putative Golgi trafficking DUF4232 PF14016.1 GAM28614.1 - 0.057 13.0 0.7 0.11 12.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) RNA_pol_Rpb4 PF03874.11 GAM28615.1 - 3.1e-09 36.8 0.3 3.2e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Plus-3 PF03126.13 GAM28616.1 - 4.3e-25 87.8 0.2 4.3e-25 87.8 0.1 3.0 3 0 0 3 3 3 1 Plus-3 domain DUF2223 PF09985.4 GAM28616.1 - 0.0053 16.1 0.2 0.011 15.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2223) EXS PF03124.9 GAM28617.1 - 3.1e-88 296.1 23.9 3.1e-88 296.1 16.6 1.4 2 0 0 2 2 2 1 EXS family SPX PF03105.14 GAM28617.1 - 7.4e-34 117.7 0.0 3.6e-19 69.6 0.0 2.9 2 1 1 3 3 3 2 SPX domain NAP PF00956.13 GAM28618.1 - 4.4e-14 52.1 13.6 7.5e-14 51.4 9.4 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF3216 PF11505.3 GAM28618.1 - 0.0069 16.1 0.0 0.03 14.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3216) BUD22 PF09073.5 GAM28618.1 - 2.8 6.9 26.0 0.06 12.4 12.4 1.9 2 0 0 2 2 2 0 BUD22 MatE PF01554.13 GAM28619.1 - 5.7e-10 39.0 16.8 3.3e-07 30.0 3.5 2.5 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.1 GAM28619.1 - 6.5e-06 26.0 4.1 6.5e-06 26.0 2.8 2.2 1 1 1 2 2 2 1 Polysaccharide biosynthesis C-terminal domain DUF1616 PF07760.6 GAM28619.1 - 0.018 14.1 1.3 0.028 13.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Sin_N PF04801.8 GAM28620.1 - 1.9e-101 340.0 13.1 3.8e-100 335.7 8.0 2.2 2 0 0 2 2 2 2 Sin-like protein conserved region PQ-loop PF04193.9 GAM28621.1 - 9.3e-21 73.1 18.9 1.9e-12 46.5 2.5 3.6 3 1 1 4 4 4 2 PQ loop repeat DUF1772 PF08592.6 GAM28621.1 - 0.58 9.8 8.2 3.4 7.4 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) SCAMP PF04144.8 GAM28621.1 - 5.9 6.7 15.1 1.1 9.0 7.4 2.0 1 1 1 2 2 2 0 SCAMP family ATP_bind_4 PF01902.12 GAM28622.1 - 1.6e-44 151.8 0.0 3.2e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 GAM28622.1 - 2.5e-25 88.5 0.0 1.4e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP P22_AR_C PF10548.4 GAM28622.1 - 0.027 14.3 0.1 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 P22AR C-terminal domain ResIII PF04851.10 GAM28623.1 - 2.5e-07 30.7 0.1 8.2e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ank_2 PF12796.2 GAM28624.1 - 2e-53 178.7 22.6 5.2e-11 42.7 0.3 4.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28624.1 - 2.4e-24 85.2 10.3 9.3e-05 22.8 0.0 6.4 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28624.1 - 7.7e-24 81.3 12.1 0.094 13.0 0.0 9.9 4 3 6 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 GAM28624.1 - 7.4e-20 70.5 18.3 0.0026 17.9 0.1 9.6 2 2 9 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.25 GAM28624.1 - 1.4e-17 62.5 8.8 0.094 12.5 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat DUF2493 PF10686.4 GAM28624.1 - 0.0021 17.5 5.9 7.9 6.1 0.0 5.2 2 1 3 6 6 6 2 Protein of unknown function (DUF2493) Lipoprot_C PF08794.5 GAM28624.1 - 0.0038 17.0 0.1 8.1 6.2 0.0 3.7 1 1 3 4 4 4 1 Lipoprotein GNA1870 C terminal like DUF1906 PF08924.6 GAM28624.1 - 0.042 13.7 0.2 6 6.7 0.0 3.9 3 1 1 5 5 5 0 Domain of unknown function (DUF1906) DUF2790 PF10976.3 GAM28624.1 - 0.064 13.0 0.2 8.7 6.2 0.0 3.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2790) PI3Ka PF00613.15 GAM28626.1 - 5e-54 182.2 1.1 1e-53 181.2 0.7 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 GAM28626.1 - 1.7e-51 175.0 0.1 3.1e-51 174.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 GAM28626.1 - 2.2e-20 72.8 0.0 4.8e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 GAM28626.1 - 1.8e-17 63.2 1.2 6.9e-17 61.3 0.0 2.5 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain SUFU_C PF12470.3 GAM28627.1 - 0.012 15.2 1.7 0.016 14.8 1.2 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain RR_TM4-6 PF06459.7 GAM28627.1 - 1.5 8.6 9.3 1.8 8.3 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CLN5 PF15014.1 GAM28628.1 - 6.6e-39 134.0 11.8 1.3e-38 133.1 8.2 1.4 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 CDP-OH_P_transf PF01066.16 GAM28629.1 - 2.8e-19 69.2 5.1 2.8e-19 69.2 3.5 3.2 1 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3810 PF12725.2 GAM28629.1 - 0.54 9.1 2.8 1.1 8.1 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) AAA_12 PF13087.1 GAM28630.1 - 1.2e-43 148.8 0.1 4.1e-43 147.0 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM28630.1 - 6e-28 98.0 3.4 6e-28 98.0 2.3 3.7 3 2 0 3 3 2 1 AAA domain AAA_30 PF13604.1 GAM28630.1 - 2e-07 30.7 0.0 0.001 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 GAM28630.1 - 1.5e-06 27.8 0.0 5.7e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain SAM_1 PF00536.25 GAM28630.1 - 0.00059 19.9 0.0 0.002 18.2 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_22 PF13401.1 GAM28630.1 - 0.0014 18.7 0.1 0.12 12.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 GAM28630.1 - 0.01 15.0 0.1 0.069 12.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SAM_PNT PF02198.11 GAM28630.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain AAA_16 PF13191.1 GAM28630.1 - 0.036 14.0 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain CheB_methylest PF01339.12 GAM28630.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 CheB methylesterase AAA_25 PF13481.1 GAM28630.1 - 0.24 10.7 0.0 0.57 9.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP41 PF04176.8 GAM28631.1 - 0.42 9.8 2.8 0.96 8.6 1.9 1.7 1 1 0 1 1 1 0 TIP41-like family DUF3374 PF11854.3 GAM28632.1 - 0.052 11.7 0.0 0.076 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) SIR2 PF02146.12 GAM28633.1 - 7.8e-58 195.1 0.0 2.3e-57 193.6 0.0 1.8 1 0 0 1 1 1 1 Sir2 family zf-UBP PF02148.14 GAM28633.1 - 4.6e-16 58.6 11.0 4.6e-16 58.6 7.6 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein SSP160 PF06933.6 GAM28633.1 - 0.026 12.5 3.0 0.038 11.9 2.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ASD2 PF08687.6 GAM28633.1 - 0.03 13.6 1.2 0.046 13.0 0.9 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 FtsH_ext PF06480.10 GAM28633.1 - 0.22 11.7 2.7 0.38 10.9 1.8 1.3 1 0 0 1 1 1 0 FtsH Extracellular DUF3795 PF12675.2 GAM28633.1 - 4.4 7.5 12.3 5.7 7.1 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3795) ELMO_CED12 PF04727.8 GAM28634.1 - 2.9e-41 140.8 1.9 5.3e-41 139.9 1.3 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Nucleotid_trans PF03407.11 GAM28636.1 - 3.1e-30 105.5 0.0 1.9e-29 102.9 0.0 2.1 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase WD40 PF00400.27 GAM28636.1 - 6.7e-25 86.0 17.0 2.1e-05 24.2 2.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-B_box PF00643.19 GAM28636.1 - 0.0015 18.4 8.4 0.0034 17.2 5.8 1.5 1 0 0 1 1 1 1 B-box zinc finger CUE PF02845.11 GAM28637.1 - 1.8e-05 24.1 0.0 7e-05 22.2 0.0 2.2 1 0 0 1 1 1 1 CUE domain Reprolysin_3 PF13582.1 GAM28637.1 - 0.0079 16.7 3.2 0.0079 16.7 2.2 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like DUF4248 PF14053.1 GAM28637.1 - 0.026 14.1 0.2 0.29 10.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) UBA PF00627.26 GAM28637.1 - 0.38 10.6 0.1 0.38 10.6 0.1 3.4 3 0 0 3 3 3 0 UBA/TS-N domain Baculo_p24 PF05073.7 GAM28637.1 - 9 5.8 28.0 0.1 12.1 5.5 2.7 3 0 0 3 3 3 0 Baculovirus P24 capsid protein ResIII PF04851.10 GAM28638.1 - 5.9e-14 52.3 0.1 9.3e-13 48.4 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM28638.1 - 2.1e-07 30.6 0.2 3.2e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 GAM28638.1 - 0.0056 15.7 0.0 0.0087 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.7 GAM28638.1 - 0.0077 14.6 0.1 0.012 13.9 0.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) ATP-synt_ab PF00006.20 GAM28638.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Helicase_C PF00271.26 GAM28638.1 - 0.016 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Kelch_6 PF13964.1 GAM28639.1 - 4.7e-14 51.8 3.1 0.00013 22.0 0.1 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.1 GAM28639.1 - 2.9e-09 36.5 5.5 0.0067 16.1 0.0 6.1 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 GAM28639.1 - 3.7e-08 32.7 0.3 1.4 8.5 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 GAM28639.1 - 1.9e-07 31.0 5.0 0.23 11.6 0.1 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain DUF3196 PF11428.3 GAM28639.1 - 0.003 16.8 3.4 0.17 11.1 0.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3196) Kelch_2 PF07646.10 GAM28639.1 - 0.021 14.6 1.2 55 3.7 0.1 4.4 5 0 0 5 5 5 0 Kelch motif Usg PF06233.7 GAM28639.1 - 0.095 12.5 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Usg-like family Kelch_5 PF13854.1 GAM28639.1 - 0.42 10.6 7.6 8.1 6.5 0.1 3.8 4 0 0 4 4 4 0 Kelch motif Thy1 PF02511.10 GAM28640.1 - 4.6e-54 182.6 0.0 5.9e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein Cyclin_N PF00134.18 GAM28641.1 - 2.7e-13 49.6 0.0 1.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 GAM28641.1 - 6.8e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3806 PF12713.2 GAM28641.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) TFIIB PF00382.14 GAM28641.1 - 0.099 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat MFS_1 PF07690.11 GAM28642.1 - 1.6e-30 105.9 65.9 6.8e-25 87.5 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM28642.1 - 0.00093 17.8 6.4 0.00093 17.8 4.5 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 GAM28642.1 - 3.5 5.9 40.6 9.6 4.4 0.6 2.3 1 1 1 2 2 2 0 MFS/sugar transport protein FNIP PF05725.7 GAM28643.1 - 3.4e-42 142.1 17.0 6.6e-09 35.5 0.0 9.7 4 3 5 10 10 10 8 FNIP Repeat F-box PF00646.28 GAM28643.1 - 0.0013 18.3 1.3 0.0024 17.4 0.1 2.2 2 0 0 2 2 2 1 F-box domain DUF4598 PF15370.1 GAM28644.1 - 7.2e-16 58.4 8.5 1.3e-15 57.6 2.5 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4598) DUF3439 PF11921.3 GAM28644.1 - 0.25 11.1 8.5 0.28 10.9 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 GAM28644.1 - 0.25 11.0 11.6 0.62 9.8 3.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Syntaphilin PF15290.1 GAM28644.1 - 1.4 8.3 10.6 0.093 12.2 3.9 1.5 2 0 0 2 2 2 0 Golgi-localised syntaxin-1-binding clamp SPATIAL PF15256.1 GAM28644.1 - 1.5 8.8 6.4 2.8 7.9 4.4 1.6 1 1 0 1 1 1 0 SPATIAL DUF2051 PF09738.4 GAM28644.1 - 6 6.0 14.5 0.059 12.6 4.6 1.5 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Ank_2 PF12796.2 GAM28645.1 - 7.4e-97 317.8 19.9 1.6e-16 60.3 0.0 6.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28645.1 - 5.3e-93 300.5 28.2 2.8e-08 33.1 0.2 13.6 12 1 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 GAM28645.1 - 4.5e-77 253.1 10.6 3.7e-12 46.4 0.0 9.4 6 2 3 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28645.1 - 1.6e-72 237.8 19.6 2.7e-10 40.1 0.2 11.9 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Sec7 PF01369.15 GAM28645.1 - 1.5e-68 230.2 2.6 2.5e-68 229.4 1.8 1.4 1 0 0 1 1 1 1 Sec7 domain Ank_3 PF13606.1 GAM28645.1 - 1.9e-62 200.8 17.0 9.4e-05 22.2 0.0 13.1 13 0 0 13 13 13 12 Ankyrin repeat PH PF00169.24 GAM28645.1 - 2.3e-22 79.1 0.4 5.3e-22 77.9 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM28645.1 - 2.4e-11 43.8 0.4 6.8e-11 42.4 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM28645.1 - 0.00087 19.3 0.0 0.024 14.6 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.1 GAM28645.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_6 PF15406.1 GAM28645.1 - 0.019 15.0 0.0 0.27 11.2 0.0 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain zf-DNL PF05180.7 GAM28646.1 - 0.052 13.2 5.0 2.1 8.1 0.6 2.6 2 0 0 2 2 2 0 DNL zinc finger Rsc14 PF08586.5 GAM28646.1 - 0.56 10.7 4.6 1.9 8.9 0.4 2.5 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Ins145_P3_rec PF08709.6 GAM28647.1 - 0.17 10.8 0.1 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Usp PF00582.21 GAM28648.1 - 2.9e-17 63.1 0.0 3.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Npa1 PF11707.3 GAM28650.1 - 2.5e-41 141.7 3.4 2.5e-41 141.7 2.3 3.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal DSPc PF00782.15 GAM28653.1 - 9.9e-27 93.1 4.4 2.1e-25 88.8 0.1 2.9 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 GAM28653.1 - 0.0032 17.5 18.4 0.0032 17.5 12.7 3.3 2 1 0 2 2 2 1 Inositol hexakisphosphate V-SNARE PF05008.10 GAM28654.1 - 1.4e-11 44.3 4.3 1.4e-11 44.3 3.0 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 GAM28654.1 - 1e-08 35.0 2.3 1e-08 35.0 1.6 3.5 2 2 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAM28654.1 - 9.6e-06 25.2 0.4 9.6e-06 25.2 0.3 2.3 2 1 0 2 2 2 1 Sec20 SNARE PF05739.14 GAM28654.1 - 0.0096 15.5 0.9 0.0096 15.5 0.6 2.6 3 1 0 3 3 3 1 SNARE domain Fusion_gly PF00523.13 GAM28654.1 - 0.016 13.2 0.9 0.029 12.4 0.6 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 Vps51 PF08700.6 GAM28654.1 - 0.041 13.7 3.8 0.51 10.2 0.1 3.0 3 0 0 3 3 3 0 Vps51/Vps67 DUF3140 PF11338.3 GAM28654.1 - 0.043 13.9 3.2 0.054 13.6 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) DUF2458 PF10454.4 GAM28654.1 - 0.048 13.5 0.2 0.048 13.5 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2458) DUF1542 PF07564.6 GAM28654.1 - 0.068 13.1 0.2 0.068 13.1 0.1 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) Phage_GPO PF05929.6 GAM28654.1 - 0.4 9.8 8.7 0.54 9.4 1.1 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.7 GAM28654.1 - 0.44 10.2 7.1 0.9 9.2 0.5 2.7 2 1 1 3 3 3 0 Laminin Domain II Fib_alpha PF08702.5 GAM28654.1 - 5.3 7.1 15.4 3.1 7.8 3.9 3.1 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 GAM28654.1 - 7.3 5.5 9.0 1.3 7.9 2.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 WH2 PF02205.15 GAM28655.1 - 6.9e-11 41.3 0.8 1.5e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 WH2 motif SH3_9 PF14604.1 GAM28655.1 - 3e-08 33.1 0.0 4.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM28655.1 - 1.2e-06 27.7 0.0 2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Pox_A_type_inc PF04508.7 GAM28655.1 - 0.00016 21.1 1.4 0.075 12.8 0.1 2.2 1 1 1 2 2 2 2 Viral A-type inclusion protein repeat HR1 PF02185.11 GAM28655.1 - 0.0041 16.8 0.6 0.0062 16.2 0.4 1.3 1 0 0 1 1 1 1 Hr1 repeat SH3_2 PF07653.12 GAM28655.1 - 0.0043 16.5 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain MscS_porin PF12795.2 GAM28655.1 - 0.011 15.0 1.6 0.015 14.6 1.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 GAM28655.1 - 0.024 14.4 0.2 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 GAM28655.1 - 0.038 13.6 0.2 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 IncA protein FliJ PF02050.11 GAM28655.1 - 0.058 13.4 0.6 0.086 12.8 0.4 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein SlyX PF04102.7 GAM28655.1 - 0.1 12.9 0.1 0.85 10.0 0.0 2.6 1 0 0 1 1 1 0 SlyX Spc7 PF08317.6 GAM28655.1 - 0.14 10.7 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 GAM28655.1 - 0.23 11.2 1.4 0.36 10.6 1.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 GAM28655.1 - 0.43 10.4 2.2 0.63 9.9 1.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PAT1 PF09770.4 GAM28655.1 - 0.75 7.9 24.6 1.1 7.4 17.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FNIP PF05725.7 GAM28656.1 - 3.1e-81 267.0 26.8 2.2e-14 53.0 0.0 9.0 7 1 2 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 GAM28656.1 - 0.00065 19.6 11.0 1.2 9.1 0.0 7.0 2 2 6 8 8 8 1 Protein of unknown function (DUF1769) MerC PF03203.9 GAM28656.1 - 0.1 12.9 0.2 3.1 8.2 0.0 2.7 2 1 0 2 2 2 0 MerC mercury resistance protein Glyco_hydro_25 PF01183.15 GAM28657.1 - 4.1e-08 33.2 0.8 6.3e-08 32.6 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Tmemb_185A PF10269.4 GAM28658.1 - 0.00045 19.9 39.7 0.051 13.1 15.6 3.9 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein Na_H_Exchanger PF00999.16 GAM28659.1 - 1.9e-52 178.0 49.3 2.2e-52 177.8 34.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2427 PF10348.4 GAM28659.1 - 0.0025 17.3 0.9 0.0025 17.3 0.6 3.4 2 2 2 4 4 4 1 Domain of unknown function (DUF2427) Amino_oxidase PF01593.19 GAM28660.1 - 2.7e-61 208.0 0.0 3.3e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 GAM28660.1 - 1.4e-17 63.4 0.2 2.7e-17 62.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 GAM28660.1 - 7.1e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 GAM28660.1 - 3.5e-05 24.1 0.0 0.00015 22.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 GAM28660.1 - 9.7e-05 21.4 0.0 0.00049 19.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 GAM28660.1 - 0.00014 20.4 0.0 0.00027 19.5 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 GAM28660.1 - 0.00037 20.6 0.0 0.0058 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 GAM28660.1 - 0.0004 19.5 0.0 0.00061 18.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 GAM28660.1 - 0.0008 18.5 0.3 0.0015 17.6 0.2 1.4 1 1 0 1 1 1 1 Thi4 family GDI PF00996.13 GAM28660.1 - 0.00081 17.8 0.2 0.0037 15.6 0.0 2.0 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 GAM28660.1 - 0.00093 19.1 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 GAM28660.1 - 0.0065 15.3 0.0 0.022 13.6 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 GAM28660.1 - 0.0067 15.3 0.0 0.062 12.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 GAM28660.1 - 0.064 12.2 0.1 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Gon7 PF08738.5 GAM28661.1 - 0.0043 17.0 4.0 0.0074 16.2 2.7 1.4 1 1 0 1 1 1 1 Gon7 family Enkurin PF13864.1 GAM28661.1 - 0.012 15.8 6.4 0.022 14.9 4.4 1.5 1 1 0 1 1 1 0 Calmodulin-binding Gp-FAR-1 PF05823.7 GAM28661.1 - 0.048 13.6 6.6 0.072 13.0 4.6 1.4 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Baculo_PEP_C PF04513.7 GAM28661.1 - 0.056 13.2 0.6 0.072 12.9 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Transcrip_act PF04949.8 GAM28661.1 - 0.073 12.6 3.8 0.21 11.1 2.7 1.7 1 1 1 2 2 2 0 Transcriptional activator Transposase_22 PF02994.9 GAM28661.1 - 0.085 11.3 9.9 0.095 11.1 6.9 1.0 1 0 0 1 1 1 0 L1 transposable element DUF4600 PF15372.1 GAM28661.1 - 0.13 12.4 6.4 0.19 11.9 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) FemAB PF02388.11 GAM28661.1 - 0.14 10.7 2.1 0.13 10.8 1.5 1.2 1 0 0 1 1 1 0 FemAB family OmpH PF03938.9 GAM28661.1 - 0.17 11.8 5.3 0.2 11.6 3.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 GAM28661.1 - 0.19 12.1 2.1 1 9.8 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Fmp27_WPPW PF10359.4 GAM28661.1 - 0.2 10.0 8.1 0.22 9.9 5.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain KMP11 PF03037.11 GAM28661.1 - 0.22 12.1 5.3 0.34 11.5 3.7 1.5 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 Atg14 PF10186.4 GAM28661.1 - 0.22 10.4 6.6 0.25 10.2 4.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mitofilin PF09731.4 GAM28661.1 - 0.33 9.5 8.6 0.38 9.3 6.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF465 PF04325.8 GAM28661.1 - 0.36 10.5 7.4 0.61 9.8 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF4145 PF13643.1 GAM28661.1 - 0.47 10.3 3.0 0.44 10.4 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) COG5 PF10392.4 GAM28661.1 - 0.66 9.9 5.6 1.9 8.4 3.9 1.8 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Bap31 PF05529.7 GAM28661.1 - 0.69 9.3 5.1 0.86 9.0 3.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Spc7 PF08317.6 GAM28661.1 - 0.92 8.1 9.2 1.1 7.8 6.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Prominin PF05478.6 GAM28661.1 - 1.2 6.5 8.5 8.8 3.7 5.9 1.8 1 1 0 1 1 1 0 Prominin Mnd1 PF03962.10 GAM28661.1 - 1.4 8.5 9.6 0.96 9.0 3.4 1.8 1 1 1 2 2 2 0 Mnd1 family DUF948 PF06103.6 GAM28661.1 - 1.9 8.3 4.4 14 5.5 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 GAM28661.1 - 2.6 6.9 8.7 2.7 6.9 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 GAM28661.1 - 3.3 7.9 8.7 3.9 7.7 6.0 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 GAM28661.1 - 3.6 5.3 6.1 3.7 5.2 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSCB_C PF07743.8 GAM28661.1 - 4.1 7.9 7.3 4.5 7.7 2.6 2.2 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain TPX2 PF06886.6 GAM28661.1 - 4.9 7.2 10.5 1.1 9.4 4.9 1.6 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Pkinase PF00069.20 GAM28662.1 - 3.5e-56 190.2 0.1 3.5e-56 190.2 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28662.1 - 1.1e-21 77.0 0.0 2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 GAM28662.1 - 0.041 13.6 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4639 PF15479.1 GAM28662.1 - 0.22 10.1 19.4 0.35 9.4 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Ded_cyto PF06920.8 GAM28663.1 - 1.5e-42 144.9 3.1 3.2e-42 143.8 2.2 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 GAM28663.1 - 4.6e-28 98.1 5.4 1.2e-22 80.4 0.8 2.5 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins Alk_phosphatase PF00245.15 GAM28664.1 - 2.5e-80 270.2 6.6 1.9e-79 267.3 4.6 2.1 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 GAM28664.1 - 0.00011 21.6 0.4 0.00031 20.2 0.3 1.7 1 0 0 1 1 1 1 Metalloenzyme superfamily Cyclase PF04199.8 GAM28664.1 - 0.041 13.5 0.1 0.088 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative cyclase Alk_phosphatase PF00245.15 GAM28665.1 - 8.3e-83 278.4 4.1 6.4e-82 275.4 2.8 2.1 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 GAM28665.1 - 0.0054 16.1 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily SKG6 PF08693.5 GAM28665.1 - 0.19 11.0 4.0 0.41 9.9 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_S49 PF01343.13 GAM28666.1 - 1e-65 220.2 0.9 2.9e-42 144.0 0.4 2.3 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.11 GAM28666.1 - 1.2e-06 27.4 0.0 2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.18 GAM28666.1 - 0.00056 19.6 2.1 0.0018 17.9 0.1 2.5 3 0 0 3 3 3 1 Clp protease DUF3395 PF11875.3 GAM28667.1 - 1.1e-37 129.0 0.6 1.8e-37 128.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 GAM28667.1 - 2.5e-21 75.1 1.3 2.5e-21 75.1 0.9 2.4 3 0 0 3 3 3 1 DnaJ domain Raptor_N PF14538.1 GAM28667.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Ras PF00071.17 GAM28668.1 - 1e-14 54.2 0.2 2.5e-13 49.7 0.1 2.2 2 0 0 2 2 2 1 Ras family Miro PF08477.8 GAM28668.1 - 8.7e-09 35.9 0.0 1.6e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM28668.1 - 0.00075 19.4 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ank_2 PF12796.2 GAM28668.1 - 0.043 14.1 0.0 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Pyrophosphatase PF00719.14 GAM28669.1 - 6.6e-50 168.5 0.1 7.9e-50 168.3 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Arf PF00025.16 GAM28670.1 - 7.2e-32 110.0 0.0 8.6e-32 109.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM28670.1 - 7.8e-06 25.1 0.0 9.8e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM28670.1 - 5.2e-05 23.7 0.0 9.6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 GAM28670.1 - 0.00011 21.6 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 GAM28670.1 - 0.00059 19.1 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 GAM28670.1 - 0.0099 14.6 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit NOG1 PF06858.9 GAM28670.1 - 0.012 15.4 0.2 0.025 14.4 0.0 1.6 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 GAM28670.1 - 0.058 13.3 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_2 PF00797.12 GAM28671.1 - 2.1e-38 132.2 0.1 2.7e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase SNARE PF05739.14 GAM28672.1 - 0.023 14.3 4.0 0.023 14.3 2.8 3.1 3 0 0 3 3 3 0 SNARE domain V-SNARE_C PF12352.3 GAM28672.1 - 0.36 10.9 5.1 0.62 10.1 0.4 2.9 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus TFIIS_C PF01096.13 GAM28673.1 - 3.4e-17 61.7 3.9 3.4e-17 61.7 2.7 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 GAM28673.1 - 0.0015 18.2 10.4 0.015 15.0 2.2 3.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 GAM28673.1 - 0.014 15.7 3.6 0.041 14.2 0.9 3.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 GAM28673.1 - 0.028 14.2 1.9 0.028 14.2 1.3 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 GAM28673.1 - 0.04 13.3 1.1 0.13 11.6 0.7 1.9 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 GAM28673.1 - 0.051 13.3 0.6 0.051 13.3 0.4 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 GAM28673.1 - 0.17 11.9 0.8 8.9 6.4 0.0 2.8 2 0 0 2 2 2 0 zinc-finger Rubredoxin PF00301.15 GAM28673.1 - 0.24 11.3 5.1 20 5.1 0.1 4.6 4 0 0 4 4 4 0 Rubredoxin Rpr2 PF04032.11 GAM28673.1 - 0.46 10.3 7.3 3 7.7 0.1 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.5 GAM28673.1 - 0.48 10.4 11.7 6.6 6.7 0.4 3.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-C4_Topoisom PF01396.14 GAM28673.1 - 1.5 8.3 12.1 4.4 6.8 2.8 3.5 2 1 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger GFA PF04828.9 GAM28673.1 - 1.9 8.5 6.9 1.5 8.7 0.1 2.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ogr_Delta PF04606.7 GAM28673.1 - 2.8 7.6 11.7 0.07 12.8 2.1 2.6 3 0 0 3 3 2 0 Ogr/Delta-like zinc finger PA26 PF04636.8 GAM28674.1 - 1.9e-140 468.5 0.1 2.5e-140 468.1 0.1 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) DUF3808 PF10300.4 GAM28675.1 - 1.9e-35 122.3 8.6 1.9e-35 122.3 5.9 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 GAM28675.1 - 0.00011 22.0 5.3 0.33 10.9 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 GAM28675.1 - 0.0079 15.9 10.3 5.7 6.9 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 GAM28675.1 - 0.017 15.0 14.3 1.7 8.7 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM28675.1 - 0.021 14.4 4.1 12 5.6 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM28675.1 - 0.033 14.5 8.0 4.7 7.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 GAM28675.1 - 0.24 11.3 0.0 0.24 11.3 0.0 3.5 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 GAM28675.1 - 0.35 11.4 16.1 0.5 10.9 0.1 6.4 8 1 0 8 8 8 0 Tetratricopeptide repeat Pkinase PF00069.20 GAM28676.1 - 1.3e-65 221.1 0.1 1.9e-65 220.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28676.1 - 2.7e-27 95.5 0.0 4.8e-27 94.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM28676.1 - 2.9e-05 23.1 0.0 6e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM28676.1 - 0.00032 19.8 0.1 0.00064 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM28676.1 - 0.001 18.8 0.0 0.0084 15.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 GAM28676.1 - 0.0054 16.3 0.7 0.0054 16.3 0.5 2.4 3 0 0 3 3 3 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 GAM28676.1 - 0.039 13.2 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Macoilin PF09726.4 GAM28676.1 - 1.4 7.1 20.8 1.3 7.2 4.5 2.1 2 0 0 2 2 2 0 Transmembrane protein FAM110_C PF14160.1 GAM28676.1 - 6.2 7.8 10.4 2.7 8.9 1.2 2.6 2 0 0 2 2 2 0 Centrosome-associated C terminus DUF515 PF04415.7 GAM28676.1 - 6.5 4.8 23.5 1.8 6.7 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Ank PF00023.25 GAM28677.1 - 3.9e-104 335.6 7.8 9.4e-11 40.9 0.0 13.3 13 0 0 13 13 13 13 Ankyrin repeat Ank_2 PF12796.2 GAM28677.1 - 5.7e-97 318.2 7.4 5.5e-20 71.4 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28677.1 - 3.8e-84 275.7 15.3 1e-10 41.8 0.0 11.4 1 1 11 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28677.1 - 9.6e-77 245.1 2.6 8.5e-07 28.6 0.1 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 GAM28677.1 - 4.7e-69 226.8 19.7 2.9e-10 40.0 0.0 10.1 2 2 10 12 12 12 12 Ankyrin repeats (many copies) CH PF00307.26 GAM28677.1 - 7.8e-12 45.2 0.2 1.7e-11 44.1 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM28677.1 - 0.00044 19.8 0.1 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Phage_T7_Capsid PF05396.6 GAM28677.1 - 0.00062 19.8 2.2 0.48 10.5 0.0 3.2 3 0 0 3 3 3 2 Phage T7 capsid assembly protein CDC24 PF06395.6 GAM28677.1 - 0.0087 16.1 0.4 0.02 14.9 0.3 1.6 1 0 0 1 1 1 1 CDC24 Calponin PK PF00224.16 GAM28678.1 - 2e-144 480.5 7.4 2.7e-144 480.0 5.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 GAM28678.1 - 8.9e-26 89.7 1.0 8.9e-26 89.7 0.7 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 GAM28678.1 - 0.00066 18.6 0.3 0.0011 17.8 0.2 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family BRCA-2_OB1 PF09103.5 GAM28678.1 - 0.015 14.9 0.0 0.23 11.1 0.0 2.7 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 PTS_2-RNA PF01885.11 GAM28679.1 - 1.3e-61 207.2 0.2 1.6e-61 206.8 0.1 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family WHIM3 PF15614.1 GAM28680.1 - 0.042 13.6 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF2999 PF11212.3 GAM28680.1 - 0.065 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) Pro_CA PF00484.14 GAM28681.1 - 1e-47 161.9 0.1 1.3e-47 161.5 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Cas_Csy2 PF09614.5 GAM28681.1 - 0.091 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Peptidase_S10 PF00450.17 GAM28682.1 - 1.1e-101 340.9 3.7 1.4e-101 340.7 2.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 GAM28682.1 - 0.0037 17.1 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 GAM28683.1 - 3e-70 229.7 35.4 3e-09 36.4 0.1 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat DUF4062 PF13271.1 GAM28683.1 - 1.3e-07 31.5 0.0 7.2e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_22 PF13401.1 GAM28683.1 - 1.9e-06 28.0 0.0 7.2e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM28683.1 - 5.5e-05 23.2 0.0 0.0014 18.6 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 GAM28683.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 GAM28683.1 - 0.029 14.6 0.7 6.4 7.0 0.0 3.2 3 0 0 3 3 3 0 ABC transporter CTP_transf_1 PF01148.15 GAM28688.1 - 2.2e-11 43.9 13.7 4.7e-09 36.2 9.5 2.1 1 1 0 1 1 1 1 Cytidylyltransferase family DUF1011 PF06237.7 GAM28688.1 - 0.01 15.6 0.6 0.081 12.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1011) B12D PF06522.6 GAM28689.1 - 3.5e-06 26.6 0.0 3.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aminotran_1_2 PF00155.16 GAM28690.1 - 1.4e-83 280.8 0.0 1.6e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1289 PF06945.8 GAM28691.1 - 9.6e-20 69.8 1.7 1e-19 69.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) BCAS2 PF05700.6 GAM28692.1 - 1.2e-52 178.5 16.1 1.5e-52 178.3 11.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) 6PF2K PF01591.13 GAM28692.1 - 0.0017 17.4 1.2 0.0017 17.4 0.8 2.0 1 1 2 3 3 3 1 6-phosphofructo-2-kinase Thioredoxin_8 PF13905.1 GAM28692.1 - 0.66 10.1 4.6 1.3 9.2 1.9 2.1 1 1 1 2 2 2 0 Thioredoxin-like Tropomyosin_1 PF12718.2 GAM28692.1 - 2.9 7.7 17.9 6.7 6.5 4.5 2.9 1 1 0 2 2 2 0 Tropomyosin like Clathrin_lg_ch PF01086.12 GAM28693.1 - 3.8e-15 56.4 19.2 3.3e-14 53.3 13.3 1.9 1 1 0 1 1 1 1 Clathrin light chain Arb2 PF09757.4 GAM28693.1 - 0.0071 15.7 0.4 0.012 15.1 0.3 1.3 1 0 0 1 1 1 1 Arb2 domain Macoilin PF09726.4 GAM28693.1 - 0.062 11.5 13.1 0.076 11.2 9.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Tantalus PF15386.1 GAM28693.1 - 0.59 9.9 3.6 1.6 8.5 2.5 1.7 1 0 0 1 1 1 0 Drosophila Tantalus-like ATP_bind_3 PF01171.15 GAM28694.1 - 1.4e-17 63.7 0.0 3.1e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 GAM28694.1 - 0.18 12.1 0.0 0.18 12.1 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2392) RecR PF02132.10 GAM28694.1 - 8.6 5.8 15.6 1.4 8.3 4.6 3.0 3 0 0 3 3 3 0 RecR protein DUF1162 PF06650.7 GAM28695.1 - 3.5e-46 157.6 7.2 9.2e-46 156.2 0.9 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 GAM28695.1 - 7.5e-40 135.1 2.8 3.5e-39 132.9 2.0 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 GAM28695.1 - 4e-06 26.8 0.1 0.00011 22.2 0.1 3.0 3 0 0 3 3 3 1 ATG C terminal domain AMP-binding PF00501.23 GAM28696.1 - 4.4e-85 285.5 0.0 5.6e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 GAM28696.1 - 2.4e-14 53.9 0.0 4.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 GAM28696.1 - 0.0067 14.9 0.1 0.017 13.6 0.0 1.6 2 0 0 2 2 2 1 GH3 auxin-responsive promoter PC_rep PF01851.17 GAM28697.1 - 2.9e-36 121.6 22.7 1.3e-07 31.4 0.1 9.2 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 GAM28697.1 - 2.3e-13 50.2 0.8 6.4e-09 35.9 0.0 4.4 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 GAM28697.1 - 1.7e-05 24.4 0.2 8.3 6.7 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 GAM28697.1 - 0.044 14.2 5.9 0.28 11.7 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat DUF2620 PF10941.3 GAM28697.1 - 0.064 13.2 0.2 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF2620 DUF3451 PF11933.3 GAM28697.1 - 2 8.1 10.2 3.5 7.3 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) AF-4 PF05110.8 GAM28698.1 - 0.068 11.0 7.6 0.062 11.1 5.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDK2AP PF09806.4 GAM28698.1 - 0.093 12.9 4.1 0.12 12.6 2.8 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DHHW PF14286.1 GAM28698.1 - 0.099 11.9 6.3 0.12 11.6 4.4 1.1 1 0 0 1 1 1 0 DHHW protein DUF947 PF06102.7 GAM28699.1 - 1.3e-43 148.7 24.3 1.3e-43 148.7 16.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF947) CENP-B_dimeris PF09026.5 GAM28699.1 - 0.57 10.4 12.2 1.9 8.7 8.5 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPR_2 PF13041.1 GAM28700.1 - 0.00053 19.9 0.9 0.0016 18.3 0.1 2.3 3 0 0 3 3 3 1 PPR repeat family FMN_dh PF01070.13 GAM28700.1 - 0.18 10.6 0.5 11 4.7 0.0 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pex14_N PF04695.8 GAM28700.1 - 1.7 8.6 8.7 4.3 7.3 6.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PspB PF06667.7 GAM28701.1 - 0.016 15.1 0.9 0.89 9.5 0.1 3.3 2 0 0 2 2 2 0 Phage shock protein B DUF3786 PF12654.2 GAM28701.1 - 0.11 11.7 1.2 0.17 11.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) Med9 PF07544.8 GAM28701.1 - 0.55 9.9 14.5 0.15 11.7 0.5 3.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Pox_A_type_inc PF04508.7 GAM28701.1 - 5.2 7.1 7.1 4.9 7.2 0.2 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Antimicrobial19 PF08225.6 GAM28702.1 - 3.5 7.1 5.2 12 5.4 0.1 3.0 3 0 0 3 3 3 0 Pseudin antimicrobial peptide LRR_2 PF07723.8 GAM28703.1 - 0.088 13.3 2.5 0.12 12.9 0.3 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat Pkinase_Tyr PF07714.12 GAM28704.1 - 0.00034 19.7 0.2 0.0012 17.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Daxx PF03344.10 GAM28704.1 - 0.39 9.1 28.1 0.017 13.6 8.2 2.2 2 0 0 2 2 2 0 Daxx Family SLBP_RNA_bind PF15247.1 GAM28705.1 - 9.7e-32 108.5 6.5 1.9e-31 107.6 4.5 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain TAFII55_N PF04658.8 GAM28705.1 - 0.064 12.7 0.2 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 TAFII55 protein conserved region DUF4637 PF15470.1 GAM28705.1 - 0.39 10.3 2.6 2.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DUF912 PF06024.7 GAM28705.1 - 7.5 6.6 10.9 3 7.9 1.8 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Aminotran_5 PF00266.14 GAM28706.1 - 1.1e-33 116.5 0.0 3.2e-33 114.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 GAM28706.1 - 1.8e-23 82.5 0.0 3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 GAM28706.1 - 7.4e-21 74.0 0.0 1.7e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 MOSC domain DUF4326 PF14216.1 GAM28706.1 - 0.011 16.2 0.0 0.039 14.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) SAM_2 PF07647.12 GAM28707.1 - 4.8e-08 32.7 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM28707.1 - 1.8e-07 31.2 0.0 4.5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_5 PF12695.2 GAM28707.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family UQ_con PF00179.21 GAM28708.1 - 1.1e-40 138.2 0.1 1.8e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ORC6 PF05460.8 GAM28708.1 - 0.015 14.4 12.4 0.019 14.0 8.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RWD PF05773.17 GAM28708.1 - 0.048 13.5 0.1 0.048 13.5 0.1 2.3 2 1 0 2 2 2 0 RWD domain Dicty_REP PF05086.7 GAM28708.1 - 0.16 9.6 18.4 0.2 9.3 12.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 GAM28708.1 - 0.29 10.8 4.1 0.55 9.9 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 GAM28708.1 - 3.1 7.5 13.3 4.3 7.0 9.2 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DEAD PF00270.24 GAM28709.1 - 2.1e-44 151.0 0.1 9.3e-44 148.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM28709.1 - 1.3e-24 85.8 0.1 2.9e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 GAM28709.1 - 0.0002 20.2 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain CytochromB561_N PF09786.4 GAM28709.1 - 0.99 7.7 7.5 1.5 7.2 5.2 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal GAS2 PF02187.12 GAM28710.1 - 0.0051 16.5 0.1 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain TMF_TATA_bd PF12325.3 GAM28711.1 - 7.6 6.2 12.9 0.27 10.9 2.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Aldo_ket_red PF00248.16 GAM28712.1 - 4.7e-43 147.0 0.0 5.4e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TraB PF01963.12 GAM28714.1 - 1.6e-21 76.9 0.1 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 TraB family Peptidase_U57 PF05582.7 GAM28714.1 - 0.077 11.9 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Pirin_C PF05726.8 GAM28715.1 - 0.097 12.7 0.4 1.3 9.1 0.0 3.0 3 0 0 3 3 3 0 Pirin C-terminal cupin domain Ank_2 PF12796.2 GAM28716.1 - 5.3e-28 97.1 1.0 1e-14 54.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28716.1 - 1.4e-23 82.8 0.3 2.2e-05 24.8 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 GAM28716.1 - 8.6e-19 66.3 2.0 1.2e-07 31.1 0.1 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 GAM28716.1 - 9.5e-16 57.4 2.3 0.00013 22.0 0.1 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28716.1 - 8.9e-15 53.3 0.7 0.00015 21.6 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat LAGLIDADG_3 PF14528.1 GAM28716.1 - 0.14 12.3 0.0 1.6 9.0 0.0 2.2 1 1 1 2 2 2 0 LAGLIDADG-like domain DDE_3 PF13358.1 GAM28717.1 - 5.1e-20 71.7 0.0 8.1e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease eIF-5_eIF-2B PF01873.12 GAM28717.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Codanin-1_C PF15296.1 GAM28717.1 - 0.085 12.7 0.1 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 Codanin-1 C-terminus HEAT PF02985.17 GAM28719.1 - 2e-05 24.2 0.4 0.45 10.7 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 GAM28719.1 - 8.9e-05 22.7 0.0 0.48 10.7 0.0 3.9 2 2 3 5 5 5 2 HEAT repeats VIT1 PF01988.14 GAM28719.1 - 0.08 12.4 0.6 0.19 11.2 0.4 1.6 1 0 0 1 1 1 0 VIT family Prefoldin PF02996.12 GAM28719.1 - 0.27 10.8 9.0 0.38 10.4 0.5 3.7 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 GAM28719.1 - 0.42 10.4 11.5 3.7 7.4 2.7 4.1 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding LisH PF08513.6 GAM28719.1 - 2.2 8.1 6.6 20 5.1 0.8 3.6 4 0 0 4 4 4 0 LisH Striatin PF08232.7 GAM28719.1 - 5.6 7.2 24.9 0.21 11.9 0.4 3.8 3 1 0 3 3 3 0 Striatin family MMR_HSR1 PF01926.18 GAM28720.1 - 1.2e-23 83.2 0.4 2.3e-23 82.3 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 GAM28720.1 - 3.2e-11 43.3 3.8 1.5e-05 24.9 0.1 3.0 2 1 1 3 3 3 2 Dynamin family KH_2 PF07650.12 GAM28720.1 - 5e-10 38.8 0.3 1.3e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 KH domain GTP_EFTU PF00009.22 GAM28720.1 - 1e-09 38.0 1.3 1.9e-07 30.7 0.9 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 GAM28720.1 - 1.2e-09 37.6 1.7 6e-09 35.3 1.2 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 GAM28720.1 - 1.3e-07 30.9 2.1 3.2e-07 29.6 1.4 1.7 1 1 0 1 1 1 1 AIG1 family Miro PF08477.8 GAM28720.1 - 4.3e-07 30.4 0.4 1.5e-06 28.6 0.3 2.1 1 1 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 GAM28720.1 - 0.00026 20.4 0.3 0.58 9.6 0.1 3.3 1 1 1 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 GAM28720.1 - 0.00048 19.3 0.0 0.00097 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 GAM28720.1 - 0.02 14.3 3.1 0.23 10.8 0.7 2.4 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 GAM28720.1 - 0.029 13.8 0.0 0.082 12.3 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4062 PF13271.1 GAM28720.1 - 0.033 14.2 0.1 2.4 8.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) ABC_tran PF00005.22 GAM28720.1 - 0.038 14.3 0.2 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter ACOX PF01756.14 GAM28721.1 - 2.5e-13 49.8 0.1 4.4e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 GAM28721.1 - 2.7e-12 45.9 0.0 6e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 GAM28721.1 - 1.8e-08 34.7 0.0 3.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 GAM28721.1 - 2.7e-05 24.3 0.0 0.00025 21.1 0.0 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM28721.1 - 0.0092 16.5 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Transcrip_reg PF01709.15 GAM28721.1 - 0.17 10.9 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator BAF1_ABF1 PF04684.8 GAM28722.1 - 4.6 5.9 17.7 9.9 4.8 12.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pyridoxal_deC PF00282.14 GAM28723.1 - 4.5e-17 61.5 0.0 8.3e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 GAM28723.1 - 1.4e-11 43.7 0.1 5.3e-11 41.8 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 GAM28723.1 - 0.0001 21.3 0.0 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 GAM28723.1 - 0.00048 19.2 0.2 0.00075 18.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Peptidase_M20 PF01546.23 GAM28724.1 - 1.5e-31 109.3 0.0 2.1e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 GAM28724.1 - 2.6e-17 62.5 0.0 4.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Hexapep PF00132.19 GAM28725.1 - 4.1e-09 35.5 14.0 3e-05 23.3 0.2 4.6 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 GAM28725.1 - 0.02 14.4 11.1 0.032 13.7 3.2 3.8 3 2 2 5 5 5 0 Hexapeptide repeat of succinyl-transferase IncA PF04156.9 GAM28726.1 - 0.00022 20.8 3.8 0.00022 20.8 2.6 1.8 1 1 1 2 2 2 1 IncA protein Hep_59 PF07052.6 GAM28726.1 - 0.012 15.9 0.1 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Pex24p PF06398.6 GAM28726.1 - 0.57 8.9 7.7 0.45 9.2 0.1 2.2 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin AIRC PF00731.15 GAM28727.1 - 2.9e-64 214.8 1.3 6.1e-64 213.8 0.9 1.6 1 0 0 1 1 1 1 AIR carboxylase SAICAR_synt PF01259.13 GAM28727.1 - 6.3e-56 189.2 0.0 1.2e-55 188.3 0.0 1.4 1 0 0 1 1 1 1 SAICAR synthetase ATP-grasp PF02222.17 GAM28727.1 - 1.1e-49 168.1 0.0 1.9e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 GAM28727.1 - 2.5e-10 40.3 0.0 5.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 GAM28727.1 - 1.7e-05 24.1 0.1 4.5e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 GAM28727.1 - 0.00012 21.5 0.2 0.00061 19.2 0.1 2.3 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 GAM28727.1 - 0.012 14.7 0.0 0.038 13.1 0.0 1.8 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3816 PF12822.2 GAM28728.1 - 0.033 14.0 1.2 0.044 13.6 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Borrelia_rep PF03183.8 GAM28728.1 - 0.1 12.4 1.8 0.26 11.1 1.3 1.7 1 0 0 1 1 1 0 Borrelia repeat protein MscS_TM PF12794.2 GAM28728.1 - 0.22 10.0 2.2 0.21 10.1 0.1 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 HIG_1_N PF04588.8 GAM28729.1 - 5.4e-10 38.8 1.8 7.6e-10 38.3 1.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region GATase PF00117.23 GAM28730.1 - 2.5e-09 36.8 0.0 5.1e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.11 GAM28730.1 - 0.00086 18.1 0.0 0.0059 15.3 0.0 2.0 2 0 0 2 2 2 1 Homoserine O-succinyltransferase Glyco_hydro_39 PF01229.12 GAM28731.1 - 3e-111 372.2 2.3 6.1e-111 371.2 1.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 MACPF PF01823.14 GAM28733.1 - 8.2e-20 71.3 3.7 1.7e-19 70.3 2.6 1.6 1 0 0 1 1 1 1 MAC/Perforin domain Ank_2 PF12796.2 GAM28735.1 - 3.7e-19 68.8 10.0 0.0012 19.1 0.0 7.8 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28735.1 - 1.1e-07 31.8 8.8 6.8 7.1 0.3 7.9 6 3 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM28735.1 - 1.4e-06 27.8 6.7 9.5 6.2 0.0 8.4 9 0 0 9 9 9 2 Ankyrin repeat Ank_3 PF13606.1 GAM28735.1 - 0.00013 21.8 16.0 4.7 7.7 0.0 10.4 11 1 1 12 12 12 1 Ankyrin repeat Ank_4 PF13637.1 GAM28735.1 - 0.043 14.3 10.5 46 4.6 0.1 7.4 6 1 2 8 8 8 0 Ankyrin repeats (many copies) DUF1443 PF07280.6 GAM28737.1 - 0.013 15.0 0.2 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1443) HNF-1B_C PF04812.8 GAM28737.1 - 0.017 14.3 1.4 0.027 13.7 1.0 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Resolvase PF00239.16 GAM28738.1 - 2.6e-08 33.8 0.1 4.8e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain Peptidase_C48 PF02902.14 GAM28741.1 - 4.2e-10 39.6 0.1 9.9e-10 38.3 0.0 1.6 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Gemini_V1 PF01524.12 GAM28741.1 - 0.0074 16.2 0.2 1.6 8.7 0.1 2.4 2 0 0 2 2 2 2 Geminivirus V1 protein Peptidase_C57 PF03290.8 GAM28741.1 - 0.043 12.3 0.6 0.056 11.9 0.4 1.2 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase DKCLD PF08068.7 GAM28741.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 DKCLD (NUC011) domain HJURP_C PF12347.3 GAM28743.1 - 0.0013 18.2 1.7 0.002 17.6 0.5 1.9 1 1 0 1 1 1 1 Holliday junction regulator protein family C-terminal repeat Med11 PF10280.4 GAM28743.1 - 0.14 12.1 3.6 0.068 13.2 0.7 1.7 2 0 0 2 2 2 0 Mediator complex protein Drf_GBD PF06371.8 GAM28743.1 - 2.6 7.3 5.4 0.45 9.8 1.1 1.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain zf-BED PF02892.10 GAM28746.1 - 0.0091 15.7 3.9 0.087 12.5 1.2 2.3 2 0 0 2 2 2 1 BED zinc finger DDE_Tnp_1_6 PF13751.1 GAM28746.1 - 0.073 13.0 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain Chromo PF00385.19 GAM28747.1 - 5.8e-15 54.6 0.3 5.8e-15 54.6 0.2 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 GAM28747.1 - 4.1e-12 46.2 0.1 7.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_4 PF13359.1 GAM28749.1 - 3.2e-06 26.8 0.9 6.6e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 DDE superfamily endonuclease Asp_protease_2 PF13650.1 GAM28751.1 - 2.1e-07 31.3 0.1 6e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 GAM28751.1 - 0.0019 18.0 3.2 0.0021 17.9 0.2 2.5 2 0 0 2 2 2 1 Retroviral aspartyl protease HSBP1 PF06825.7 GAM28751.1 - 0.012 15.1 0.1 0.049 13.2 0.0 2.0 1 0 0 1 1 1 0 Heat shock factor binding protein 1 gag-asp_proteas PF13975.1 GAM28751.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4172 PF13776.1 GAM28751.1 - 0.12 12.4 2.4 0.39 10.8 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) HSBP1 PF06825.7 GAM28752.1 - 0.0038 16.7 0.0 0.0099 15.4 0.0 1.7 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2344 PF10105.4 GAM28752.1 - 0.035 13.5 0.2 0.055 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Flu_PB1 PF00602.12 GAM28752.1 - 0.081 10.6 0.2 0.087 10.5 0.1 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 DUF605 PF04652.11 GAM28752.1 - 1.9 7.8 7.3 2.3 7.5 5.0 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 GAM28752.1 - 4.8 5.2 15.5 5.2 5.1 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Viral_protease PF08715.5 GAM28753.1 - 0.045 12.8 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Papain like viral protease Myb_DNA-binding PF00249.26 GAM28754.1 - 3.4e-21 75.0 4.8 3.5e-12 46.1 0.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain SWIRM PF04433.12 GAM28754.1 - 2.6e-19 69.1 1.9 6.3e-19 67.8 0.0 2.6 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 GAM28754.1 - 1.3e-12 47.5 5.6 3.8e-07 30.0 0.2 3.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain JAB PF01398.16 GAM28754.1 - 3.6e-12 46.0 0.0 3.6e-12 46.0 0.0 3.2 3 1 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 GAM28754.1 - 2.3e-10 39.9 0.1 3e-09 36.3 0.0 2.6 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain DUF2457 PF10446.4 GAM28754.1 - 0.001 17.9 34.8 0.001 17.9 24.1 4.1 3 1 1 4 4 4 1 Protein of unknown function (DUF2457) Daxx PF03344.10 GAM28754.1 - 0.1 11.0 42.0 0.092 11.2 7.5 2.4 2 0 0 2 2 2 0 Daxx Family ResIII PF04851.10 GAM28755.1 - 1.3e-16 60.9 0.6 1.3e-16 60.9 0.4 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 GAM28755.1 - 2.4e-06 27.1 0.1 8.5e-06 25.3 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC2_membrane_3 PF12698.2 GAM28755.1 - 5.5 5.9 14.7 0.47 9.4 1.4 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein Asp PF00026.18 GAM28756.1 - 9.3e-30 103.9 1.3 4.1e-29 101.8 0.9 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 GAM28756.1 - 1.5e-11 44.4 2.7 3.7e-11 43.2 1.9 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 GAM28756.1 - 1.8e-06 27.6 0.1 1.9e-05 24.2 0.0 2.5 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal zf-RanBP PF00641.13 GAM28757.1 - 6.1e-05 22.0 5.0 6.1e-05 22.0 3.4 4.5 4 0 0 4 4 4 2 Zn-finger in Ran binding protein and others Nop14 PF04147.7 GAM28757.1 - 0.00018 19.6 35.1 0.00018 19.6 24.3 4.4 3 1 0 3 3 3 2 Nop14-like family DZR PF12773.2 GAM28757.1 - 0.25 11.2 28.2 0.54 10.1 0.6 4.4 4 0 0 4 4 4 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 GAM28757.1 - 1.3 9.1 6.1 12 6.0 0.0 3.5 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase WD40 PF00400.27 GAM28763.1 - 5.5e-45 149.7 20.7 1.5e-10 40.5 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 GAM28763.1 - 1.8e-43 148.3 0.3 3.9e-43 147.2 0.2 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split RR_TM4-6 PF06459.7 GAM28763.1 - 1.8 8.4 6.6 3 7.6 4.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.8 GAM28763.1 - 2 7.5 10.0 4 6.5 6.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Kelch_4 PF13418.1 GAM28764.1 - 5.5e-54 179.7 12.6 4.3e-10 39.1 0.2 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 GAM28764.1 - 2.4e-50 167.6 10.4 3.5e-11 42.9 0.0 8.3 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM28764.1 - 6.8e-38 128.0 6.4 5.1e-09 35.8 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM28764.1 - 2.1e-36 122.5 14.5 1.9e-07 30.9 0.2 6.5 2 2 4 6 6 6 5 Kelch motif Kelch_2 PF07646.10 GAM28764.1 - 2.1e-30 103.3 10.7 2.1e-06 27.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 GAM28764.1 - 1.6e-24 85.1 5.8 1e-06 28.1 0.0 6.2 6 0 0 6 6 6 4 Kelch motif zf-C3HC4_3 PF13920.1 GAM28764.1 - 2.6e-12 46.2 10.2 4.5e-12 45.4 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.12 GAM28764.1 - 7.3e-06 25.7 7.7 7.3e-06 25.7 5.3 3.2 2 1 1 3 3 3 1 K-box region zf-C3HC4_2 PF13923.1 GAM28764.1 - 0.0002 21.3 13.1 0.00037 20.4 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.4 GAM28764.1 - 0.027 14.4 3.0 0.11 12.5 2.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Prok-RING_4 PF14447.1 GAM28764.1 - 0.032 13.7 4.7 0.075 12.5 3.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3328 PF11807.3 GAM28764.1 - 3.5 7.2 6.9 0.48 10.0 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) TIG PF01833.19 GAM28765.1 - 3.3e-09 36.6 50.0 3.6e-06 26.8 2.0 8.6 6 3 3 9 9 9 4 IPT/TIG domain EGF_2 PF07974.8 GAM28765.1 - 0.032 14.3 9.5 0.068 13.3 6.6 1.6 1 0 0 1 1 1 0 EGF-like domain ABC_membrane PF00664.18 GAM28766.1 - 1.4e-68 231.2 47.6 2.5e-39 135.3 12.3 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM28766.1 - 1.3e-52 177.7 1.8 7e-28 97.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.18 GAM28766.1 - 3.2e-09 36.7 0.6 0.00096 19.1 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 GAM28766.1 - 1.6e-08 33.8 1.0 1.1e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 GAM28766.1 - 1e-07 31.4 8.6 0.016 14.4 0.2 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 GAM28766.1 - 4.5e-07 29.2 0.4 0.016 14.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 GAM28766.1 - 2.9e-06 27.7 0.2 0.14 12.6 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 GAM28766.1 - 7.7e-06 26.0 0.3 0.024 14.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 GAM28766.1 - 8.6e-06 25.6 2.9 0.00064 19.5 0.0 3.2 3 0 0 3 3 3 1 Dynamin family AAA_17 PF13207.1 GAM28766.1 - 1.1e-05 26.2 0.2 0.15 12.8 0.0 3.0 2 1 1 3 3 2 2 AAA domain AAA_21 PF13304.1 GAM28766.1 - 3.5e-05 23.9 0.3 1.1 9.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 GAM28766.1 - 0.00022 20.3 0.3 0.13 11.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 GAM28766.1 - 0.00045 19.9 0.6 0.16 11.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 GAM28766.1 - 0.001 18.6 1.5 0.59 9.5 0.0 3.7 4 0 0 4 4 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 GAM28766.1 - 0.0013 18.2 0.1 0.47 9.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 GAM28766.1 - 0.0027 17.8 0.5 1.4 9.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 GAM28766.1 - 0.0038 16.0 0.8 1.8 7.2 0.1 2.3 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 GAM28766.1 - 0.0052 16.2 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 GAM28766.1 - 0.0054 15.6 0.2 1.7 7.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 GAM28766.1 - 0.0055 17.0 0.4 6.7 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 GAM28766.1 - 0.007 16.7 10.5 3.1 8.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM28766.1 - 0.0091 16.1 0.0 9 6.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ABC_ATPase PF09818.4 GAM28766.1 - 0.019 13.5 1.9 9.9 4.6 0.0 3.5 3 1 0 3 3 3 0 Predicted ATPase of the ABC class UPF0079 PF02367.12 GAM28766.1 - 0.023 14.3 0.2 0.44 10.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 GAM28766.1 - 0.024 13.5 0.1 4.4 6.1 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF87 PF01935.12 GAM28766.1 - 0.036 13.8 5.8 0.48 10.2 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 GAM28766.1 - 0.04 13.3 0.0 5.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP-synt_ab PF00006.20 GAM28766.1 - 0.044 13.2 0.2 1.6 8.2 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 GAM28766.1 - 0.052 13.1 0.5 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 GAM28766.1 - 0.076 12.5 0.7 2.9 7.3 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 GAM28766.1 - 0.082 12.7 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 GAM28766.1 - 0.097 11.4 2.6 1.1 8.0 0.3 2.5 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) cobW PF02492.14 GAM28766.1 - 0.1 12.0 0.8 0.68 9.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 GAM28766.1 - 0.15 11.1 1.8 1.4 8.0 0.1 2.5 2 0 0 2 2 2 0 AIG1 family FGGY_N PF00370.16 GAM28767.1 - 1.6e-52 178.2 0.0 2.2e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 GAM28767.1 - 1e-27 97.0 1.2 1.5e-27 96.5 0.8 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ank_2 PF12796.2 GAM28770.1 - 1.4e-60 201.5 18.4 7e-16 58.3 0.1 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) RabGAP-TBC PF00566.13 GAM28770.1 - 3.5e-54 183.5 5.0 5.9e-54 182.7 3.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank PF00023.25 GAM28770.1 - 1.4e-37 125.6 9.8 3.1e-07 29.8 0.0 9.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 GAM28770.1 - 1.3e-28 98.8 7.5 8.2e-07 29.3 0.1 7.8 3 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28770.1 - 4.1e-25 87.2 4.0 9e-07 28.9 0.0 6.6 4 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28770.1 - 4.9e-25 85.0 5.8 0.001 19.0 0.0 9.9 9 0 0 9 9 9 8 Ankyrin repeat COX6B PF02297.12 GAM28770.1 - 2.7 8.0 5.8 24 5.0 0.2 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb AAA_18 PF13238.1 GAM28773.1 - 6.4e-27 94.3 0.5 9.8e-27 93.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 GAM28773.1 - 3.4e-14 53.7 0.1 4.6e-14 53.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 GAM28773.1 - 1.9e-05 24.5 0.2 0.0028 17.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 GAM28773.1 - 3.5e-05 23.8 0.0 7.6e-05 22.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain dNK PF01712.14 GAM28773.1 - 0.00016 21.6 0.8 0.00025 20.9 0.5 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase ResIII PF04851.10 GAM28773.1 - 0.00026 20.8 0.0 0.00075 19.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SKI PF01202.17 GAM28773.1 - 0.0011 18.8 0.2 0.0061 16.4 0.1 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_16 PF13191.1 GAM28773.1 - 0.0021 18.0 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 GAM28773.1 - 0.0053 16.4 0.2 0.0083 15.8 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 GAM28773.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 GAM28773.1 - 0.0097 15.2 1.7 0.033 13.5 0.2 2.0 2 0 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.1 GAM28773.1 - 0.01 16.0 0.0 0.036 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain CoaE PF01121.15 GAM28773.1 - 0.012 15.0 0.8 2.1 7.7 0.0 2.6 1 1 2 3 3 3 0 Dephospho-CoA kinase DUF2075 PF09848.4 GAM28773.1 - 0.014 14.3 0.0 0.034 13.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 GAM28773.1 - 0.017 15.3 0.2 0.056 13.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 GAM28773.1 - 0.02 14.4 0.7 0.034 13.7 0.0 1.8 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.9 GAM28773.1 - 0.024 14.3 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 GAM28773.1 - 0.025 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.5 GAM28773.1 - 0.026 13.7 0.1 0.075 12.2 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KaiC PF06745.8 GAM28773.1 - 0.027 13.5 0.3 0.05 12.7 0.0 1.6 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 GAM28773.1 - 0.04 13.0 0.0 0.084 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 GAM28773.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 NTPase ADK PF00406.17 GAM28773.1 - 0.066 13.0 0.4 4.7 7.0 0.0 2.6 2 1 0 2 2 2 0 Adenylate kinase AAA_14 PF13173.1 GAM28773.1 - 0.067 13.0 0.7 0.21 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 GAM28773.1 - 0.085 12.2 0.3 0.18 11.2 0.2 1.8 1 1 1 2 2 2 0 AAA-like domain SRPRB PF09439.5 GAM28773.1 - 0.12 11.5 0.3 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.1 GAM28773.1 - 0.13 11.8 0.2 0.21 11.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 GAM28773.1 - 0.13 11.1 0.3 0.21 10.4 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein BRF1 PF07741.8 GAM28773.1 - 0.49 10.6 3.2 1 9.6 0.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Alk_phosphatase PF00245.15 GAM28774.1 - 1.2e-83 281.1 10.6 2.8e-83 279.9 7.3 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 GAM28774.1 - 4.1e-05 23.1 0.8 0.0001 21.7 0.6 1.6 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-met2 PF12907.2 GAM28775.1 - 3.4e-05 23.7 0.8 5.3e-05 23.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 GAM28775.1 - 0.00014 22.4 9.3 0.0002 21.9 6.5 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.2 GAM28775.1 - 0.009 16.1 1.6 0.014 15.5 1.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 GAM28775.1 - 0.014 15.4 0.7 0.022 14.8 0.5 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 GAM28775.1 - 0.023 14.9 0.7 0.036 14.3 0.5 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger Eapp_C PF10238.4 GAM28775.1 - 2.8 7.8 6.4 7.8 6.4 4.5 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein ATE_C PF04377.10 GAM28776.1 - 1e-46 158.1 1.8 1e-46 158.1 1.3 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 GAM28776.1 - 8.6e-19 67.1 0.6 2e-18 65.9 0.4 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Fer2_4 PF13510.1 GAM28777.1 - 0.34 10.7 4.8 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Dickkopf_N PF04706.7 GAM28777.1 - 2.5 8.3 15.7 0.92 9.7 0.8 3.4 2 1 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region SGL PF08450.7 GAM28778.1 - 1.1e-67 227.9 0.2 1.4e-67 227.6 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 GAM28778.1 - 0.0059 16.4 1.6 7.4 6.9 0.0 3.9 4 0 0 4 4 4 2 Two component regulator propeller PQQ_2 PF13360.1 GAM28778.1 - 0.036 13.5 0.2 0.93 8.9 0.1 2.2 1 1 1 2 2 2 0 PQQ-like domain RCC1 PF00415.13 GAM28779.1 - 1.1e-68 227.2 9.9 1.3e-12 47.7 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM28779.1 - 1.7e-39 132.6 26.0 5.2e-11 41.8 0.2 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 GAM28779.1 - 5.2e-20 71.4 5.2 5.4e-16 58.5 1.6 2.4 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.10 GAM28779.1 - 0.015 15.1 0.8 0.065 13.0 0.0 2.4 2 1 1 3 3 3 0 BTB And C-terminal Kelch EF-hand_2 PF09068.6 GAM28779.1 - 0.053 13.5 0.2 0.18 11.8 0.3 1.8 2 0 0 2 2 2 0 EF hand V-SNARE PF05008.10 GAM28781.1 - 5.7e-13 48.8 3.8 5.7e-13 48.8 2.7 2.4 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 GAM28781.1 - 2.2e-12 46.8 3.5 2.2e-12 46.8 2.4 3.1 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 GAM28781.1 - 4.1e-05 23.1 0.3 4.1e-05 23.1 0.2 2.4 3 1 0 3 3 2 1 Sec20 DUF1542 PF07564.6 GAM28781.1 - 0.001 19.0 4.0 0.001 19.0 2.8 1.9 2 1 0 2 2 1 1 Domain of Unknown Function (DUF1542) DUF3596 PF12167.3 GAM28781.1 - 0.0015 18.0 0.1 0.0034 16.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3596) Fusion_gly PF00523.13 GAM28781.1 - 0.0018 16.4 0.5 0.0018 16.4 0.3 1.8 2 1 0 2 2 2 1 Fusion glycoprotein F0 Synaptobrevin PF00957.16 GAM28781.1 - 0.089 12.4 0.3 0.089 12.4 0.2 2.4 2 1 0 2 2 2 0 Synaptobrevin Spectrin PF00435.16 GAM28781.1 - 0.093 13.0 5.4 2.5 8.4 2.0 3.0 2 1 0 3 3 3 0 Spectrin repeat Mnd1 PF03962.10 GAM28781.1 - 0.095 12.3 9.0 0.022 14.4 2.3 2.2 2 1 0 2 2 2 0 Mnd1 family DUF4650 PF15509.1 GAM28781.1 - 0.15 10.9 3.4 0.22 10.3 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Pex24p PF06398.6 GAM28781.1 - 0.15 10.8 0.1 0.15 10.8 0.1 2.0 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Apq12 PF12716.2 GAM28781.1 - 0.47 10.1 7.3 0.65 9.7 5.1 1.2 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Laminin_II PF06009.7 GAM28781.1 - 0.56 9.9 8.7 1.6 8.4 0.1 2.7 2 1 1 3 3 3 0 Laminin Domain II Syntaxin_2 PF14523.1 GAM28781.1 - 0.69 9.9 11.7 8.3 6.5 3.9 3.2 2 1 1 3 3 3 0 Syntaxin-like protein DUF3735 PF12537.3 GAM28781.1 - 1.1 9.3 4.5 10 6.2 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3735) COG2 PF06148.6 GAM28781.1 - 1.2 8.9 5.2 7.3 6.4 0.1 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 E2R135 PF11570.3 GAM28781.1 - 1.6 8.7 8.4 1.2 9.2 3.9 2.0 1 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 CENP-H PF05837.7 GAM28781.1 - 1.7 8.8 7.6 2.8 8.1 1.2 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PilJ PF13675.1 GAM28781.1 - 2.1 8.7 7.7 3.8 7.8 1.5 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-Q PF13094.1 GAM28781.1 - 3.7 7.5 8.4 13 5.8 5.8 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 GAM28781.1 - 5.2 6.8 10.7 10 5.8 5.7 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein E1-E2_ATPase PF00122.15 GAM28782.1 - 1.9e-46 157.9 5.8 1.9e-46 157.9 4.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 GAM28782.1 - 6.9e-33 114.8 0.0 3e-32 112.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 GAM28782.1 - 1.4e-23 83.4 9.1 1.4e-23 83.4 6.3 3.8 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 GAM28782.1 - 5.7e-18 64.6 0.0 1.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 GAM28782.1 - 2.1e-14 54.1 0.2 1.2e-13 51.6 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 GAM28782.1 - 2.7e-11 42.7 0.0 9.5e-11 41.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 GAM28782.1 - 0.00025 20.6 0.0 0.00065 19.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.7 GAM28782.1 - 0.049 13.2 3.8 0.72 9.5 0.1 3.0 2 0 0 2 2 2 0 Mpv17 / PMP22 family NT-C2 PF10358.4 GAM28784.1 - 3.7e-26 91.3 4.7 3.7e-26 91.3 3.3 2.4 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 GAM28784.1 - 4.2e-20 71.5 0.1 1.6e-19 69.7 0.1 2.1 1 0 0 1 1 1 1 DIL domain SlyX PF04102.7 GAM28784.1 - 0.00023 21.4 35.3 0.38 11.1 2.2 7.8 6 1 1 7 7 7 3 SlyX ACDC PF14733.1 GAM28784.1 - 0.013 15.5 0.3 0.013 15.5 0.2 3.1 3 0 0 3 3 3 0 AP2-coincident C-terminal ADIP PF11559.3 GAM28784.1 - 0.014 15.3 1.1 0.014 15.3 0.7 7.1 4 2 2 6 6 6 0 Afadin- and alpha -actinin-Binding DAD PF02109.11 GAM28785.1 - 3.8e-44 149.3 6.6 4.2e-44 149.2 4.5 1.0 1 0 0 1 1 1 1 DAD family Ald_Xan_dh_C2 PF02738.13 GAM28786.1 - 3.8e-193 642.7 0.0 5.1e-193 642.3 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 GAM28786.1 - 3.9e-49 166.3 0.1 8.7e-49 165.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 GAM28786.1 - 7.6e-32 109.3 0.0 1.6e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 GAM28786.1 - 4.8e-30 103.8 0.3 1e-29 102.8 0.2 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 GAM28786.1 - 2.7e-29 100.8 0.1 5.7e-29 99.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 GAM28786.1 - 3.4e-09 36.3 1.2 8.7e-09 35.0 0.0 2.4 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Formyl_trans_N PF00551.14 GAM28788.1 - 0.038 13.5 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Formyl transferase RFX_DNA_binding PF02257.10 GAM28788.1 - 0.069 13.3 0.1 0.072 13.2 0.1 1.1 1 0 0 1 1 1 0 RFX DNA-binding domain DUF3644 PF12358.3 GAM28790.1 - 0.043 14.0 0.3 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) TOBE_3 PF12857.2 GAM28791.1 - 0.06 13.2 0.0 8.6 6.2 0.0 2.2 1 1 1 2 2 2 0 TOBE-like domain SAM_PNT PF02198.11 GAM28793.1 - 0.1 12.3 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DDE_Tnp_4 PF13359.1 GAM28798.1 - 8.6e-08 31.9 0.9 1.3e-06 28.0 0.6 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 GAM28798.1 - 0.056 13.6 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain FNIP PF05725.7 GAM28799.1 - 1.1e-12 47.6 0.5 2.1e-07 30.8 0.0 4.0 3 1 1 4 4 4 3 FNIP Repeat FNIP PF05725.7 GAM28800.1 - 5.7e-39 131.8 3.7 4.7e-12 45.6 0.1 4.2 3 1 1 4 4 4 4 FNIP Repeat HSP33 PF01430.14 GAM28801.1 - 5.1e-35 120.9 0.0 5.8e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein PLDc_2 PF13091.1 GAM28802.1 - 5.5e-18 64.9 0.0 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM28802.1 - 4.1e-07 29.5 0.2 0.0015 18.2 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif AAA PF00004.24 GAM28803.1 - 2.7e-41 140.8 0.0 4.9e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 GAM28803.1 - 1.1e-05 25.1 0.0 5.4e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM28803.1 - 1.8e-05 24.9 0.0 0.0014 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAM28803.1 - 0.00049 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM28803.1 - 0.00067 19.7 0.0 0.0019 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 GAM28803.1 - 0.0013 17.7 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 GAM28803.1 - 0.0022 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 GAM28803.1 - 0.0031 17.6 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 GAM28803.1 - 0.0053 17.5 0.0 0.012 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 GAM28803.1 - 0.0068 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 GAM28803.1 - 0.0075 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 GAM28803.1 - 0.011 15.4 0.1 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 GAM28803.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAM28803.1 - 0.018 14.1 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 GAM28803.1 - 0.03 13.0 0.0 0.053 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 GAM28803.1 - 0.035 13.6 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 GAM28803.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 GAM28803.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 GAM28803.1 - 0.078 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 GAM28803.1 - 0.096 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 GAM28803.1 - 0.11 12.1 0.0 15 5.2 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 GAM28803.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RhoGEF PF00621.15 GAM28804.1 - 1.7e-40 138.8 1.8 2.5e-40 138.2 1.3 1.3 1 0 0 1 1 1 1 RhoGEF domain Rap_GAP PF02145.10 GAM28805.1 - 1.4e-58 197.3 0.2 3.4e-58 196.1 0.1 1.7 1 0 0 1 1 1 1 Rap/ran-GAP ECIST_Cterm PF14784.1 GAM28805.1 - 0.24 11.3 4.8 0.85 9.5 3.3 1.9 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein MFS_1 PF07690.11 GAM28807.1 - 2.1e-33 115.4 26.8 2.3e-27 95.6 2.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM28807.1 - 4.3e-14 51.9 4.9 4.3e-14 51.9 3.4 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 GAM28807.1 - 1.6e-05 23.4 5.2 1.6e-05 23.4 3.6 4.6 2 1 2 5 5 5 1 MFS/sugar transport protein MFS_1_like PF12832.2 GAM28807.1 - 0.001 18.8 5.5 0.015 15.0 0.1 3.6 4 0 0 4 4 4 1 MFS_1 like family IncA PF04156.9 GAM28807.1 - 0.049 13.2 0.1 0.5 9.9 0.0 2.8 2 0 0 2 2 2 0 IncA protein Pyrophosphatase PF00719.14 GAM28808.1 - 8.1e-46 155.3 1.4 1.1e-45 154.8 1.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF3596 PF12167.3 GAM28808.1 - 0.13 11.8 0.1 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) PP2C PF00481.16 GAM28809.1 - 3.3e-48 164.3 0.3 2.8e-34 118.6 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 GAM28809.1 - 0.00016 21.1 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4370 PF14290.1 GAM28809.1 - 0.84 9.0 9.1 0.41 10.0 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4370) Herpes_capsid PF06112.6 GAM28810.1 - 0.33 10.9 16.6 0.53 10.3 11.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 GAM28810.1 - 0.37 9.0 15.7 0.47 8.6 10.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Ret_tiss PF10044.4 GAM28810.1 - 2 9.0 6.1 14 6.2 0.6 2.5 2 0 0 2 2 2 0 Retinal tissue protein DNA_pol_viral_N PF00242.12 GAM28810.1 - 2.3 7.1 15.7 3.3 6.6 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RAP1 PF07218.6 GAM28810.1 - 6.6 4.7 12.4 8.8 4.2 8.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAP_GLY PF01302.20 GAM28812.1 - 3.6e-14 52.2 0.2 6.2e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 GAM28812.1 - 1.5e-11 43.8 30.8 8.1e-05 22.3 5.4 5.0 4 1 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 GAM28812.1 - 1.7e-11 43.4 41.4 6.1e-05 22.5 1.1 5.6 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 GAM28812.1 - 3.6e-05 23.4 29.5 0.2 11.8 0.1 8.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 GAM28812.1 - 0.0014 18.4 33.4 0.93 9.7 0.2 8.4 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.1 GAM28812.1 - 0.022 14.3 0.1 0.022 14.3 0.1 3.2 2 1 2 4 4 4 0 Leucine-rich repeat LRR_7 PF13504.1 GAM28812.1 - 0.17 12.1 37.3 0.37 11.1 0.4 8.2 8 1 1 9 9 9 0 Leucine rich repeat SLY PF12485.3 GAM28812.1 - 4.4 7.5 6.6 2.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein LIM PF00412.17 GAM28813.1 - 4.8e-35 119.4 46.2 5.9e-12 45.4 4.5 5.3 5 0 0 5 5 5 5 LIM domain Rap_GAP PF02145.10 GAM28814.1 - 2.9e-57 193.1 0.1 6.4e-57 191.9 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Arm PF00514.18 GAM28814.1 - 0.012 15.3 0.1 0.042 13.6 0.1 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Sporozoite_P67 PF05642.6 GAM28814.1 - 0.013 13.3 1.0 0.021 12.7 0.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RuBisCO_large PF00016.15 GAM28814.1 - 0.24 10.2 0.0 0.48 9.2 0.0 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Abhydrolase_6 PF12697.2 GAM28815.1 - 3.9e-27 95.6 0.0 5.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM28815.1 - 4e-19 69.0 0.0 1.8e-18 66.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM28815.1 - 1.8e-11 43.9 0.0 9.9e-11 41.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM28815.1 - 0.0032 17.2 0.0 0.0089 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase DUF915 PF06028.6 GAM28815.1 - 0.0093 15.0 0.0 0.021 13.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 GAM28815.1 - 0.027 12.9 0.0 0.04 12.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family UPF0227 PF05728.7 GAM28815.1 - 0.041 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Esterase PF00756.15 GAM28815.1 - 0.05 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 GAM28815.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Tetraspannin PF00335.15 GAM28816.1 - 4.4e-30 104.6 16.8 5.3e-30 104.3 11.6 1.0 1 0 0 1 1 1 1 Tetraspanin family Herpes_UL43 PF05072.8 GAM28816.1 - 0.026 13.3 5.4 0.93 8.1 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL43 protein FA_desaturase PF00487.19 GAM28816.1 - 0.071 12.5 0.2 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF4131 PF13567.1 GAM28816.1 - 0.44 9.9 8.1 1.2 8.5 3.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3042 PF11240.3 GAM28816.1 - 0.77 9.6 5.7 3.4 7.5 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) MARVEL PF01284.18 GAM28816.1 - 2.8 7.7 19.3 2.6 7.8 7.3 2.2 1 1 1 2 2 2 0 Membrane-associating domain Sex_peptide PF08138.6 GAM28816.1 - 3.4 7.5 0.0 3.4 7.5 0.0 3.2 3 0 0 3 3 3 0 Sex peptide (SP) family DUF843 PF05814.6 GAM28816.1 - 4.2 7.2 5.7 0.54 10.0 0.1 2.3 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Ribosomal_L44 PF00935.14 GAM28817.1 - 1.6e-30 104.9 12.3 1.6e-30 104.9 8.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 SH3_2 PF07653.12 GAM28818.1 - 1.2e-14 53.5 0.1 1.9e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 GAM28818.1 - 1.2e-12 47.2 0.1 1.7e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 GAM28818.1 - 7.4e-11 41.2 0.2 1.1e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain zinc_ribbon_2 PF13240.1 GAM28818.1 - 0.00058 19.2 3.8 0.00094 18.5 2.7 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 GAM28818.1 - 0.0012 18.5 0.5 0.0021 17.8 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 GAM28818.1 - 0.0013 17.8 2.9 0.0022 17.1 2.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-C3HC4_3 PF13920.1 GAM28818.1 - 0.062 12.9 1.5 0.094 12.3 1.1 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CTP_transf_2 PF01467.21 GAM28819.1 - 7.3e-34 117.0 0.0 2.1e-19 70.1 0.0 2.3 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 GAM28819.1 - 1.9e-05 24.3 3.8 1.1 8.8 0.2 3.6 3 1 0 3 3 3 3 FAD synthetase Lactamase_B_3 PF13483.1 GAM28819.1 - 0.0014 18.3 0.1 0.086 12.5 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain U3_assoc_6 PF08640.6 GAM28819.1 - 0.047 13.4 1.0 0.087 12.5 0.7 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 adh_short PF00106.20 GAM28820.1 - 1.1e-24 87.2 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM28820.1 - 6.6e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 GAM28820.1 - 0.0019 17.9 0.3 0.0041 16.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 GAM28820.1 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Luteo_PO PF04662.8 GAM28820.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Luteovirus P0 protein GIDA PF01134.17 GAM28821.1 - 1.2e-153 511.5 0.1 1.7e-153 511.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 GAM28821.1 - 3.1e-22 78.4 0.0 7.3e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 GAM28821.1 - 1.3e-06 27.7 0.4 1.3e-06 27.7 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 GAM28821.1 - 1.7e-06 28.0 1.5 4.7e-06 26.6 0.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 GAM28821.1 - 0.00076 18.4 7.1 0.0026 16.6 2.2 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 GAM28821.1 - 0.0092 14.9 4.8 0.23 10.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 GAM28821.1 - 0.039 13.0 1.6 0.53 9.3 0.2 2.4 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 GAM28821.1 - 0.039 13.5 0.3 0.1 12.1 0.2 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 GAM28821.1 - 0.055 13.8 0.6 0.14 12.5 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 GAM28821.1 - 0.058 11.8 5.2 0.25 9.7 1.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 GAM28821.1 - 0.11 11.1 4.6 4.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 GAM28821.1 - 0.18 11.5 1.4 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FNIP PF05725.7 GAM28822.1 - 5e-67 221.6 4.0 5.7e-10 38.9 0.0 8.5 6 1 4 10 10 10 10 FNIP Repeat LRR_5 PF13306.1 GAM28822.1 - 1.8e-09 37.3 0.0 0.077 12.7 0.0 4.1 1 1 3 4 4 4 3 Leucine rich repeats (6 copies) Podoplanin PF05808.6 GAM28823.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Podoplanin Y_Y_Y PF07495.8 GAM28823.1 - 0.034 13.8 4.7 0.16 11.7 0.0 4.2 5 0 0 5 5 5 0 Y_Y_Y domain DUF2012 PF09430.5 GAM28823.1 - 0.28 11.0 2.7 3.7 7.4 0.0 3.7 2 1 1 4 4 4 0 Protein of unknown function (DUF2012) PH PF00169.24 GAM28824.1 - 1.1e-19 70.5 0.5 2.4e-19 69.4 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM28824.1 - 6.3e-09 36.0 2.9 3.5e-07 30.4 1.8 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM28824.1 - 0.00019 21.4 0.6 0.00052 20.0 0.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.5 GAM28824.1 - 0.0038 17.1 0.1 0.2 11.6 0.0 2.3 1 1 1 2 2 2 1 Plant pleckstrin homology-like region PH_9 PF15410.1 GAM28824.1 - 0.0041 17.2 1.4 0.084 13.0 1.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 GAM28824.1 - 0.11 12.3 0.2 6.8 6.6 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain FNIP PF05725.7 GAM28825.1 - 3.2e-63 209.4 6.7 9.2e-10 38.3 0.0 7.7 4 2 4 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 GAM28825.1 - 1.5e-08 34.4 0.0 0.02 14.6 0.0 3.6 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) F-box PF00646.28 GAM28825.1 - 0.013 15.1 1.8 0.034 13.7 1.2 1.7 1 0 0 1 1 1 0 F-box domain ParBc_2 PF08857.6 GAM28825.1 - 0.68 9.7 2.6 21 4.9 0.0 4.3 4 2 3 7 7 7 0 Putative ParB-like nuclease RabGAP-TBC PF00566.13 GAM28827.1 - 2e-49 168.0 0.1 3.5e-49 167.1 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.2 GAM28827.1 - 0.0081 15.8 0.5 0.036 13.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM28827.1 - 0.027 14.1 0.7 0.095 12.3 0.3 2.1 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.20 GAM28828.1 - 1.8e-70 237.0 0.0 2.9e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28828.1 - 3.2e-35 121.4 0.0 4.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 GAM28828.1 - 3.8e-16 59.1 1.3 5.2e-16 58.7 0.3 1.7 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 GAM28828.1 - 5.4e-08 32.6 0.6 1.4e-07 31.3 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM28828.1 - 1.6e-07 31.5 1.5 1.7e-06 28.2 1.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.19 GAM28828.1 - 1.2e-06 28.9 1.0 1.2e-06 28.9 0.7 1.7 2 0 0 2 2 2 1 Protein kinase C terminal domain PH_9 PF15410.1 GAM28828.1 - 1.6e-05 25.0 1.7 0.00016 21.8 0.3 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 GAM28828.1 - 2.3e-05 24.3 1.2 3.6e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 GAM28828.1 - 0.0012 17.9 0.0 0.03 13.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PH_6 PF15406.1 GAM28828.1 - 0.012 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain ANTH PF07651.11 GAM28829.1 - 3.7e-51 173.4 1.1 3.7e-51 173.4 0.8 2.4 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 GAM28829.1 - 3.3e-08 33.4 0.0 9.1e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 ENTH domain Cupin_8 PF13621.1 GAM28830.1 - 2.3e-32 112.4 0.1 3.1e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 GAM28830.1 - 1.6e-05 25.1 0.4 0.0001 22.5 0.1 2.3 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 GAM28830.1 - 0.0008 18.8 0.2 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 GAM28830.1 - 0.08 12.4 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.17 GAM28831.1 - 3.8e-24 84.0 5.3 1.4e-08 34.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM28831.1 - 9.6e-16 57.5 0.8 4.1e-05 23.4 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM28831.1 - 2.7e-10 39.9 2.7 3.9e-06 26.6 0.1 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2404 PF10296.4 GAM28832.1 - 0.00023 21.2 0.0 0.00069 19.6 0.0 1.8 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Sec7 PF01369.15 GAM28834.1 - 3e-51 173.7 0.8 6.6e-51 172.6 0.6 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 GAM28834.1 - 1.2e-19 70.4 0.7 4.4e-19 68.6 0.5 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM28834.1 - 4.1e-07 30.2 0.5 4.1e-07 30.2 0.3 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain PUCC PF03209.10 GAM28834.1 - 0.00093 18.0 2.2 0.0014 17.4 1.5 1.2 1 0 0 1 1 1 1 PUCC protein PH_8 PF15409.1 GAM28834.1 - 0.008 16.2 0.3 0.38 10.8 0.2 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain UQ_con PF00179.21 GAM28835.1 - 2.5e-42 143.6 0.1 4.1e-42 142.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.1 GAM28835.1 - 3.8e-16 59.6 0.0 8.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Prok-E2_B PF14461.1 GAM28835.1 - 9e-07 28.7 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Rad60-SLD PF11976.3 GAM28835.1 - 5.2e-06 26.0 0.9 1.1e-05 24.9 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 GAM28835.1 - 0.0059 15.9 0.2 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 GAM28835.1 - 0.028 14.9 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD VWA PF00092.23 GAM28835.1 - 0.033 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain FNIP PF05725.7 GAM28836.1 - 1.9e-50 168.5 38.2 2.2e-12 46.6 3.5 8.3 6 2 3 9 9 9 8 FNIP Repeat LIM PF00412.17 GAM28838.1 - 1.7e-30 104.8 36.2 1.2e-11 44.4 6.4 3.1 3 0 0 3 3 3 3 LIM domain zf-C3HC4_3 PF13920.1 GAM28838.1 - 0.001 18.6 31.1 0.48 10.1 5.1 4.5 3 2 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) Sgf11 PF08209.6 GAM28838.1 - 0.12 11.6 0.2 0.12 11.6 0.1 4.7 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) DUF1364 PF07102.7 GAM28838.1 - 2.2 8.1 19.2 7.8 6.4 2.3 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1364) IF-2B PF01008.12 GAM28840.1 - 7.8e-65 218.6 0.0 9.4e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family YqzL PF14006.1 GAM28840.1 - 0.079 13.1 0.1 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 YqzL-like protein Tyr_Deacylase PF02580.11 GAM28841.1 - 1.6e-33 115.7 0.0 1.8e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SAC3_GANP PF03399.11 GAM28841.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PKD_channel PF08016.7 GAM28842.1 - 3.9e-11 42.0 4.0 1.1e-10 40.5 2.8 1.8 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 GAM28842.1 - 6.2e-06 25.6 25.1 6.2e-06 25.6 17.4 3.0 3 1 1 4 4 4 1 Ion transport protein ScpA_ScpB PF02616.9 GAM28842.1 - 0.07 12.7 5.8 0.13 11.8 4.0 1.3 1 0 0 1 1 1 0 ScpA/B protein XPG_N PF00752.12 GAM28843.1 - 2.5e-24 85.4 0.0 6.5e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 GAM28843.1 - 1.1e-23 83.0 0.4 4.5e-23 81.1 0.2 2.2 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 GAM28843.1 - 1.4e-06 28.0 0.0 3.8e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 GAM28843.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat 5_3_exonuc PF01367.15 GAM28843.1 - 0.022 15.0 0.1 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold PI3_PI4_kinase PF00454.22 GAM28844.1 - 3.8e-36 124.7 0.3 3.1e-35 121.7 0.2 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 GAM28844.1 - 9.7e-32 109.6 0.0 2.1e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.24 GAM28844.1 - 6.2e-10 39.2 0.4 2.1e-09 37.5 0.3 2.0 1 0 0 1 1 1 1 PH domain PI3K_C2 PF00792.19 GAM28844.1 - 5.7e-05 22.9 0.1 0.00034 20.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 PH_11 PF15413.1 GAM28844.1 - 0.038 14.2 0.5 2.4 8.4 0.3 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain FNIP PF05725.7 GAM28845.1 - 1.4e-62 207.4 17.3 3.6e-10 39.6 0.1 6.6 6 0 0 6 6 6 6 FNIP Repeat LRR_5 PF13306.1 GAM28845.1 - 1.3e-05 24.8 0.0 0.18 11.5 0.0 2.8 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) ECH PF00378.15 GAM28846.1 - 6.2e-51 172.8 2.1 1.1e-50 172.1 1.4 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3867 PF12983.2 GAM28846.1 - 0.0079 16.1 0.2 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3867) PTS_IIA PF02255.11 GAM28846.1 - 0.012 15.4 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit TA0956 PF11513.3 GAM28846.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 P4Ha_N PF08336.6 GAM28846.1 - 0.13 12.1 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Methyltransf_16 PF10294.4 GAM28847.1 - 1.8e-17 63.3 0.0 2.6e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 GAM28847.1 - 3.4e-08 33.3 0.0 6.5e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM28847.1 - 9.5e-06 26.1 0.0 2.4e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM28847.1 - 0.00022 20.8 0.5 0.0031 17.1 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 GAM28847.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 GAM28847.1 - 0.025 15.0 0.0 0.063 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 GAM28847.1 - 0.032 14.7 0.0 0.076 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Lipoprotein_17 PF04200.7 GAM28847.1 - 0.12 12.5 2.1 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein associated domain EF-hand_7 PF13499.1 GAM28848.1 - 0.031 14.4 0.1 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair ORC4_C PF14629.1 GAM28848.1 - 0.058 12.7 3.8 0.16 11.2 2.6 1.7 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus SapB_2 PF03489.12 GAM28849.1 - 2.2e-21 75.4 2.0 1.9e-09 37.3 0.3 3.2 2 0 0 2 2 2 2 Saposin-like type B, region 2 SapB_1 PF05184.10 GAM28849.1 - 1e-15 57.1 12.4 2.6e-08 33.4 1.3 3.2 3 0 0 3 3 3 2 Saposin-like type B, region 1 Tbf5 PF06331.7 GAM28849.1 - 0.00091 18.9 1.1 1.5 8.6 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIH complex subunit Tfb5 HypD PF01924.11 GAM28849.1 - 0.017 13.8 2.3 0.55 8.9 0.1 2.1 1 1 1 2 2 2 0 Hydrogenase formation hypA family tRNA_bind_2 PF13725.1 GAM28849.1 - 0.068 13.2 0.0 0.32 11.1 0.0 2.0 1 1 0 1 1 1 0 Possible tRNA binding domain DUF836 PF05768.9 GAM28849.1 - 0.14 12.4 3.4 4.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Helicase_C PF00271.26 GAM28849.1 - 0.14 12.0 0.0 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Helicase conserved C-terminal domain NADH-G_4Fe-4S_3 PF10588.4 GAM28849.1 - 1.7 7.9 5.2 5.3 6.3 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region MACPF PF01823.14 GAM28850.1 - 2.7e-17 63.1 3.6 3.4e-17 62.8 2.5 1.1 1 0 0 1 1 1 1 MAC/Perforin domain FTHFS PF01268.14 GAM28850.1 - 0.001 17.1 0.0 0.0016 16.5 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase BRCT PF00533.21 GAM28851.1 - 3.3e-09 36.7 0.3 5.3e-07 29.6 0.2 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM28851.1 - 0.0011 18.8 0.2 0.0024 17.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain CRAL_TRIO PF00650.15 GAM28852.1 - 1.3e-35 122.2 0.0 1.9e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 GAM28852.1 - 8.3e-09 35.4 1.5 2e-08 34.2 1.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM28852.1 - 9.7e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1754 PF08555.5 GAM28852.1 - 0.43 11.2 3.2 1.1 9.9 2.2 1.6 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) C2 PF00168.25 GAM28853.1 - 7.5e-26 89.8 0.4 1.1e-25 89.2 0.3 1.3 1 0 0 1 1 1 1 C2 domain Nucleoplasmin PF03066.10 GAM28854.1 - 1.6 8.1 6.8 4.3 6.8 2.3 2.3 2 0 0 2 2 2 0 Nucleoplasmin TMEM210 PF15195.1 GAM28855.1 - 0.04 14.0 0.1 0.075 13.1 0.1 1.4 1 0 0 1 1 1 0 TMEM210 family PIG-Y PF15159.1 GAM28855.1 - 0.14 12.4 4.3 4.8 7.4 0.2 2.5 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y TMEM154 PF15102.1 GAM28855.1 - 3.6 7.2 4.7 6.3 6.5 0.5 2.2 1 1 1 2 2 2 0 TMEM154 protein family Methyltransf_12 PF08242.7 GAM28856.1 - 0.087 13.3 1.4 0.44 11.0 1.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Gifsy-2 PF13856.1 GAM28857.1 - 0.024 14.7 0.3 5.9 7.0 0.0 4.0 4 0 0 4 4 4 0 ATP-binding sugar transporter from pro-phage DUF4083 PF13314.1 GAM28857.1 - 0.18 11.6 0.8 0.48 10.2 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) FNIP PF05725.7 GAM28858.1 - 7.8e-17 60.9 4.6 3.3e-05 23.7 0.0 5.8 5 1 1 6 6 6 5 FNIP Repeat TTL PF03133.10 GAM28860.1 - 2.6e-21 75.8 0.2 8.8e-13 47.8 0.1 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 GAM28860.1 - 9.2e-05 21.3 0.0 0.013 14.2 0.0 2.7 3 1 0 3 3 3 2 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 GAM28860.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus CP_ATPgrasp_1 PF04174.8 GAM28860.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp 5_nucleotid PF05761.9 GAM28861.1 - 7.6e-176 585.0 4.8 9e-176 584.7 3.3 1.0 1 0 0 1 1 1 1 5' nucleotidase family Menin PF05053.8 GAM28863.1 - 0.029 12.5 0.5 0.042 12.0 0.3 1.2 1 0 0 1 1 1 0 Menin FR47 PF08445.5 GAM28864.1 - 1.7e-14 53.3 0.0 3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 GAM28864.1 - 8.7e-06 25.6 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 GAM28864.1 - 0.00014 21.9 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 GAM28864.1 - 0.00041 20.4 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 GAM28864.1 - 0.00051 20.2 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM28864.1 - 0.04 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 GAM28864.1 - 0.043 13.8 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_9 PF13527.1 GAM28864.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ank_4 PF13637.1 GAM28865.1 - 6.1e-06 26.6 0.4 0.99 9.9 0.0 4.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28865.1 - 7e-06 25.7 1.2 0.9 9.9 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 GAM28865.1 - 0.00027 21.1 0.3 0.042 14.1 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28865.1 - 0.00077 19.1 0.1 0.66 9.9 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Herpes_UL31 PF02718.9 GAM28867.1 - 0.028 13.1 0.1 0.052 12.2 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL31-like protein DUF202 PF02656.10 GAM28868.1 - 8.6e-12 45.1 5.4 8.6e-12 45.1 3.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2956 PF11169.3 GAM28868.1 - 0.016 15.1 0.2 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF3483 PF11982.3 GAM28868.1 - 0.03 13.5 0.3 0.038 13.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF2207 PF09972.4 GAM28868.1 - 0.22 10.0 2.3 0.41 9.1 1.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.2 GAM28868.1 - 0.93 8.4 7.0 0.46 9.4 2.7 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein Bax1-I PF01027.15 GAM28868.1 - 1.6 8.2 10.4 3.8 7.0 7.2 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Polysacc_synt_C PF14667.1 GAM28868.1 - 2.7 7.7 14.5 1.1 9.0 2.4 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Skp1 PF01466.14 GAM28869.1 - 8.2e-41 137.9 0.1 1.5e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 GAM28869.1 - 7.7e-27 93.1 0.2 2.2e-26 91.7 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.26 GAM28869.1 - 0.24 11.4 1.8 10 6.2 0.1 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain zf-C3HC4_3 PF13920.1 GAM28870.1 - 1.6e-08 34.1 15.4 1.6e-08 34.1 10.7 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM28870.1 - 4.6e-08 32.6 19.1 4.6e-08 32.6 13.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM28870.1 - 8.2e-07 28.7 17.0 8.2e-07 28.7 11.8 2.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 GAM28870.1 - 4.5e-06 26.5 19.6 4.5e-06 26.5 13.6 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM28870.1 - 1.5e-05 24.5 17.5 1.5e-05 24.5 12.1 3.0 2 2 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 GAM28870.1 - 0.00013 21.8 0.1 0.00035 20.4 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 GAM28870.1 - 0.005 16.6 17.3 0.005 16.6 12.0 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 GAM28870.1 - 0.0058 16.3 8.7 0.0058 16.3 6.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 GAM28870.1 - 0.011 15.5 8.8 0.011 15.5 6.1 3.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Nucleopor_Nup85 PF07575.8 GAM28871.1 - 5.3e-59 199.9 20.5 1.2e-57 195.4 10.8 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin S10_plectin PF03501.10 GAM28872.1 - 1.2e-37 127.6 0.1 1.5e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Pex14_N PF04695.8 GAM28873.1 - 3.3e-29 101.6 10.9 3.3e-29 101.6 7.5 6.1 4 3 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 GAM28873.1 - 0.00038 20.0 0.4 0.00038 20.0 0.2 3.6 3 1 0 3 3 3 1 IncA protein RhoGEF PF00621.15 GAM28874.1 - 6.3e-40 136.9 0.6 1.3e-39 135.9 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM28874.1 - 9.8e-08 32.1 2.7 1.2e-07 31.9 0.4 2.2 3 0 0 3 3 3 1 PH domain Arm PF00514.18 GAM28874.1 - 5e-07 29.3 20.4 0.0013 18.4 0.1 6.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 GAM28874.1 - 0.0011 19.2 0.7 4.9 7.5 0.0 4.2 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 GAM28874.1 - 0.0049 16.8 0.4 2.6 8.3 0.1 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 GAM28874.1 - 0.019 15.4 0.2 5.3 7.6 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat Atx10homo_assoc PF09759.4 GAM28874.1 - 0.026 14.2 0.6 0.24 11.1 0.1 2.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain GST_C_2 PF13410.1 GAM28875.1 - 1.5e-08 34.3 0.3 3.1e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM28875.1 - 2.6e-08 33.9 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 GAM28875.1 - 1.6e-06 27.9 0.1 3.1e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM28875.1 - 3.5e-06 27.0 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM28875.1 - 4.9e-05 23.2 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain WD40 PF00400.27 GAM28876.1 - 8.5e-28 95.1 0.0 7.4e-05 22.4 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 GAM28876.1 - 0.0011 18.7 0.0 0.0082 15.9 0.0 2.3 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Coatomer_WDAD PF04053.9 GAM28876.1 - 0.0025 16.7 0.3 0.031 13.0 0.0 2.0 1 1 2 3 3 3 1 Coatomer WD associated region Nup160 PF11715.3 GAM28876.1 - 0.0034 15.5 0.1 0.51 8.4 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 GAM28876.1 - 0.011 15.2 0.1 0.1 12.0 0.0 2.3 1 1 1 2 2 2 0 PQQ-like domain DUF3312 PF11768.3 GAM28876.1 - 0.035 12.3 0.1 0.051 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Clavanin PF05452.6 GAM28876.1 - 0.049 13.6 0.3 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 Clavanin CTP_transf_1 PF01148.15 GAM28877.1 - 2.3e-10 40.5 21.2 3.5e-09 36.6 14.9 2.8 1 1 1 2 2 2 1 Cytidylyltransferase family HTH_36 PF13730.1 GAM28877.1 - 0.031 14.4 0.4 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Gate PF07670.9 GAM28877.1 - 3.8 7.4 9.9 5.8 6.8 2.0 3.2 2 1 0 2 2 2 0 Nucleoside recognition PPR_2 PF13041.1 GAM28878.1 - 1.2e-18 66.8 0.4 2e-10 40.5 0.0 4.3 2 1 2 4 4 4 4 PPR repeat family PPR_3 PF13812.1 GAM28878.1 - 1.6e-12 46.6 0.4 0.0062 16.7 0.0 4.4 4 0 0 4 4 4 4 Pentatricopeptide repeat domain PPR PF01535.15 GAM28878.1 - 1.2e-10 40.5 0.8 0.11 12.5 0.0 4.4 4 0 0 4 4 4 4 PPR repeat PPR_1 PF12854.2 GAM28878.1 - 1.7e-05 24.2 0.9 0.24 10.8 0.0 4.3 4 0 0 4 4 4 2 PPR repeat Ribosomal_S2 PF00318.15 GAM28879.1 - 7.2e-44 149.5 2.3 2.9e-21 75.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S18 PF01084.15 GAM28880.1 - 1.4e-14 53.6 0.0 9.2e-14 51.0 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S18 Peptidase_S13 PF02113.10 GAM28881.1 - 5.3e-79 265.7 0.0 6.3e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family ubiquitin PF00240.18 GAM28882.1 - 4.5e-07 29.1 0.4 0.0023 17.3 0.0 2.9 3 1 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.3 GAM28882.1 - 4.8e-05 22.9 0.4 0.029 14.0 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 GAM28882.1 - 0.0035 17.8 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 2 WXG100 protein secretion system (Wss), protein YukD Lipocalin_2 PF08212.7 GAM28882.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Lipocalin-like domain ubiquitin PF00240.18 GAM28883.1 - 0.00049 19.4 1.4 0.00052 19.3 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 GAM28883.1 - 0.1 12.3 0.8 0.23 11.1 0.0 2.0 2 1 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like FKBP_C PF00254.23 GAM28885.1 - 1.4e-16 60.2 0.0 3.4e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 GAM28885.1 - 0.0005 19.6 0.2 0.049 13.2 0.1 2.6 2 0 0 2 2 2 1 TPR repeat EXS PF03124.9 GAM28885.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 EXS family TPR_2 PF07719.12 GAM28885.1 - 9.3 6.4 8.5 2.5 8.2 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat FNIP PF05725.7 GAM28886.1 - 1.9e-90 296.5 14.6 9e-11 41.5 0.1 8.6 5 2 3 8 8 8 8 FNIP Repeat Fork_head PF00250.13 GAM28887.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Fork head domain RFC1 PF08519.7 GAM28888.1 - 9.1e-36 122.9 0.1 5.6e-35 120.4 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 GAM28888.1 - 4.5e-14 52.7 0.2 2.5e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 GAM28888.1 - 1.1e-13 51.1 0.0 3.8e-13 49.3 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_22 PF13401.1 GAM28888.1 - 0.0012 19.0 0.3 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 GAM28888.1 - 0.037 13.0 0.0 0.08 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 GAM28888.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 GAM28888.1 - 0.55 11.0 0.0 0.55 11.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain HATPase_c PF02518.21 GAM28889.1 - 2.6e-26 91.5 0.1 5.7e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 GAM28889.1 - 2.3e-15 56.3 0.1 4.8e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 GAM28889.1 - 6.7e-15 55.0 0.0 4.3e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain GAF_2 PF13185.1 GAM28889.1 - 0.002 18.6 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c_2 PF13581.1 GAM28889.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Ank_2 PF12796.2 GAM28891.1 - 0.0021 18.3 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28891.1 - 0.03 14.5 0.2 3.1 8.1 0.0 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Sod_Cu PF00080.15 GAM28892.1 - 1.6e-27 96.4 8.5 2.5e-22 79.5 0.3 3.2 3 0 0 3 3 3 2 Copper/zinc superoxide dismutase (SODC) FNIP PF05725.7 GAM28893.1 - 6.5e-37 125.2 14.5 6.6e-10 38.7 0.2 7.7 6 1 2 8 8 8 7 FNIP Repeat Choline_kin_N PF04428.9 GAM28893.1 - 0.0036 16.7 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 Choline kinase N terminus Adaptin_N PF01602.15 GAM28894.1 - 1e-159 532.2 14.1 1.4e-159 531.7 9.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 GAM28894.1 - 5.5e-31 107.7 5.9 5.5e-29 101.2 0.2 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 GAM28894.1 - 2.5e-20 72.5 1.3 1.3e-06 28.5 0.0 5.6 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 GAM28894.1 - 9.8e-11 40.8 4.2 0.06 13.4 0.0 6.1 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.3 GAM28894.1 - 9.8e-08 31.6 1.4 0.0065 15.8 0.1 4.1 3 2 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 GAM28894.1 - 1.2e-05 25.6 0.4 6.9 7.2 0.0 5.9 5 2 1 6 6 6 1 HEAT-like repeat Cnd3 PF12719.2 GAM28894.1 - 0.00015 20.8 0.8 0.0018 17.3 0.1 2.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 GAM28894.1 - 0.0015 18.2 6.0 6 6.8 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 GAM28894.1 - 0.007 16.0 0.1 2.5 7.8 0.0 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain TPR_19 PF14559.1 GAM28894.1 - 0.0091 16.3 0.8 0.096 13.0 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat B2-adapt-app_C PF09066.5 GAM28895.1 - 1.1e-22 80.0 0.3 1.7e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.15 GAM28895.1 - 6.9e-07 29.5 0.4 1.2e-06 28.8 0.3 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Phage_rep_org_N PF09681.5 GAM28895.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Ank_2 PF12796.2 GAM28896.1 - 1.7e-58 194.9 1.7 1.1e-13 51.3 0.0 5.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28896.1 - 1.9e-49 163.0 3.5 1.1e-07 31.2 0.1 10.1 10 0 0 10 10 10 10 Ankyrin repeat Ank_4 PF13637.1 GAM28896.1 - 1.3e-44 149.7 0.4 2.4e-09 37.4 0.0 7.4 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28896.1 - 4.2e-39 128.6 0.1 4.9e-05 23.1 0.0 10.3 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 GAM28896.1 - 1.5e-28 98.1 3.1 7.1e-06 26.1 0.0 7.8 2 2 7 9 9 9 9 Ankyrin repeats (many copies) YfmQ PF10787.4 GAM28896.1 - 0.0076 15.6 0.0 2.3 7.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein from bacillus cereus group PPR PF01535.15 GAM28896.1 - 0.052 13.5 0.0 3.6 7.7 0.0 3.1 3 0 0 3 3 3 0 PPR repeat Thaumatin PF00314.12 GAM28897.1 - 5e-84 281.0 12.3 5.7e-84 280.8 8.6 1.0 1 0 0 1 1 1 1 Thaumatin family Pico_P2A PF00947.14 GAM28897.1 - 0.0056 16.4 0.5 0.013 15.3 0.3 1.6 1 0 0 1 1 1 1 Picornavirus core protein 2A Eaf7 PF07904.8 GAM28898.1 - 5.1e-13 48.8 0.3 7.7e-13 48.2 0.2 1.3 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Mito_carr PF00153.22 GAM28899.1 - 2.2e-65 216.3 9.1 2.1e-22 78.6 0.0 3.3 4 0 0 4 4 4 3 Mitochondrial carrier protein Hist_deacetyl PF00850.14 GAM28900.1 - 1.8e-90 303.3 0.0 3.1e-90 302.6 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Zn_Tnp_IS1 PF03811.8 GAM28900.1 - 0.059 12.8 4.5 0.15 11.5 3.1 1.7 1 0 0 1 1 1 0 InsA N-terminal domain AAA_22 PF13401.1 GAM28901.1 - 0.00089 19.4 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Nop14 PF04147.7 GAM28902.1 - 0.22 9.4 11.5 0.22 9.3 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 GAM28902.1 - 0.92 8.4 9.9 1.4 7.8 6.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 GAM28902.1 - 3 5.7 7.8 3.8 5.4 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein FNIP PF05725.7 GAM28903.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 FNIP Repeat CPSF100_C PF13299.1 GAM28904.1 - 4.5e-22 78.9 4.3 4.5e-19 69.2 0.0 3.4 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 GAM28904.1 - 2.5e-18 66.2 0.0 6.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 GAM28904.1 - 2.7e-07 30.3 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 GAM28904.1 - 1.6e-06 27.7 0.0 3.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 GAM28904.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RCC1 PF00415.13 GAM28906.1 - 2.4e-60 200.5 10.5 1.9e-12 47.2 0.0 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM28906.1 - 1.2e-26 91.6 15.5 7.1e-05 22.3 0.0 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat TIR_2 PF13676.1 GAM28906.1 - 0.019 15.1 0.0 9.9 6.3 0.0 3.3 2 1 0 2 2 2 0 TIR domain Nucleoside_tran PF01733.13 GAM28907.1 - 3e-48 164.5 19.9 7.5e-48 163.2 13.8 1.7 1 1 0 1 1 1 1 Nucleoside transporter COX7C PF02935.11 GAM28907.1 - 0.056 13.2 3.4 0.82 9.5 0.0 3.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DUF808 PF05661.7 GAM28907.1 - 0.14 10.9 0.5 0.24 10.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) DIOX_N PF14226.1 GAM28908.1 - 6.9e-23 81.3 0.0 9.9e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 GAM28908.1 - 9.2e-20 70.7 0.0 2.1e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily LOH1CR12 PF10158.4 GAM28909.1 - 0.037 13.8 4.5 0.021 14.6 0.8 2.4 2 0 0 2 2 2 0 Tumour suppressor protein Cupin_4 PF08007.7 GAM28910.1 - 2.4e-64 217.5 1.1 2.5e-64 217.5 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.1 GAM28910.1 - 1.1e-07 31.5 3.0 1.1e-06 28.3 2.1 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.17 GAM28910.1 - 0.00042 19.7 0.0 0.00087 18.7 0.0 1.5 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 GAM28910.1 - 0.0026 17.2 0.0 0.03 13.8 0.0 2.7 3 0 0 3 3 3 1 Cupin domain Rrn6 PF10214.4 GAM28910.1 - 3.1 5.7 7.2 4.2 5.3 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA PF00004.24 GAM28912.1 - 8.7e-42 142.4 0.0 1.4e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 GAM28912.1 - 4.7e-07 29.9 0.1 8.2e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 GAM28912.1 - 1.3e-05 25.1 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 GAM28912.1 - 3.5e-05 22.8 0.0 6e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAM28912.1 - 7.2e-05 22.5 1.3 0.00029 20.5 0.2 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM28912.1 - 0.00014 21.8 0.1 0.0005 20.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 GAM28912.1 - 0.0006 18.7 0.0 0.087 11.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain RuvB_N PF05496.7 GAM28912.1 - 0.00077 18.5 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 GAM28912.1 - 0.0046 16.0 0.2 0.26 10.3 0.1 2.3 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.12 GAM28912.1 - 0.0053 16.1 0.1 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 GAM28912.1 - 0.0083 15.8 0.1 0.13 11.9 0.0 2.2 1 1 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 GAM28912.1 - 0.0086 15.5 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 GAM28912.1 - 0.01 15.5 0.2 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 GAM28912.1 - 0.011 15.0 0.5 0.16 11.3 0.1 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAM28912.1 - 0.015 15.4 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 GAM28912.1 - 0.016 13.9 0.1 0.033 12.9 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 GAM28912.1 - 0.017 15.4 0.1 0.045 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 GAM28912.1 - 0.017 14.7 0.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 GAM28912.1 - 0.019 14.1 0.1 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 GAM28912.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 GAM28912.1 - 0.026 15.3 0.1 0.075 13.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 GAM28912.1 - 0.027 14.5 0.0 0.091 12.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 GAM28912.1 - 0.028 14.3 0.1 0.073 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 GAM28912.1 - 0.029 13.9 0.1 0.088 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 GAM28912.1 - 0.045 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 GAM28912.1 - 0.052 13.4 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 GAM28912.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 GAM28912.1 - 0.094 11.6 0.1 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thioredox_DsbH PF03190.10 GAM28913.1 - 9.5e-74 246.5 0.1 3.6e-73 244.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 GAM28913.1 - 2e-10 40.5 0.0 4.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 GAM28913.1 - 8.7e-08 31.6 3.9 0.00016 21.0 0.1 3.2 2 1 1 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_88 PF07470.8 GAM28913.1 - 2.6e-05 23.4 2.5 0.11 11.5 0.1 3.1 2 2 0 3 3 3 2 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.1 GAM28913.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_76 PF03663.9 GAM28913.1 - 0.022 14.1 1.8 0.21 10.9 0.3 2.5 2 1 0 2 2 2 0 Glycosyl hydrolase family 76 DUF1680 PF07944.7 GAM28913.1 - 0.06 11.6 0.8 3.5 5.7 0.0 2.4 2 1 1 3 3 3 0 Putative glycosyl hydrolase of unknown function (DUF1680) Ndr PF03096.9 GAM28914.1 - 1e-63 214.4 0.1 1.2e-63 214.2 0.1 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 GAM28914.1 - 3.9e-11 43.2 0.0 5.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 GAM28914.1 - 2.6e-05 23.8 0.0 3.4e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold EIAV_GP90 PF00971.13 GAM28914.1 - 0.013 13.9 0.0 0.021 13.3 0.0 1.3 1 0 0 1 1 1 0 EIAV coat protein, gp90 RIO1 PF01163.17 GAM28915.1 - 1.2e-75 253.0 0.1 2.1e-75 252.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 GAM28915.1 - 0.012 14.6 0.1 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 GAM28915.1 - 0.018 14.2 0.1 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 GAM28915.1 - 0.03 14.0 0.0 6.1 6.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Actino_peptide PF14408.1 GAM28915.1 - 0.43 10.5 6.1 1.4 8.9 4.2 1.9 1 1 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes YL1 PF05764.8 GAM28915.1 - 1.3 8.6 14.3 2.2 7.8 9.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein RIO1 PF01163.17 GAM28916.1 - 3.5e-75 251.5 0.1 3.5e-75 251.5 0.1 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 GAM28916.1 - 0.02 13.9 0.1 0.43 9.6 0.1 2.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma70_ner PF04546.8 GAM28916.1 - 0.13 11.8 27.2 0.08 12.5 8.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region YL1 PF05764.8 GAM28916.1 - 0.23 11.0 42.7 1.3 8.5 14.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein DUF2796 PF10986.3 GAM28916.1 - 1.1 9.2 17.3 1.6 8.6 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) SDA1 PF05285.7 GAM28916.1 - 3.3 6.9 35.6 3.3 6.9 5.5 2.2 2 0 0 2 2 2 0 SDA1 Mtc PF03820.12 GAM28917.1 - 8.2e-98 326.8 0.0 9.2e-98 326.6 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier zf-DNL PF05180.7 GAM28918.1 - 4.7e-27 93.5 0.6 4.7e-27 93.5 0.4 2.1 2 0 0 2 2 2 1 DNL zinc finger Cytadhesin_P30 PF07271.6 GAM28918.1 - 0.26 10.5 4.4 0.4 9.9 3.1 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Got1 PF04178.7 GAM28919.1 - 8.1e-18 64.6 13.7 9e-18 64.4 9.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 GAM28919.1 - 0.056 12.4 15.6 0.12 11.3 10.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF308 PF03729.8 GAM28919.1 - 0.73 9.8 15.6 0.29 11.1 9.1 1.6 1 1 0 1 1 1 0 Short repeat of unknown function (DUF308) DUF1129 PF06570.6 GAM28919.1 - 3.9 6.7 6.5 4.7 6.4 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MR_MLE_C PF13378.1 GAM28921.1 - 1.1e-13 51.1 0.1 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 GAM28921.1 - 2.8e-05 24.1 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 GAM28921.1 - 5.9e-05 23.5 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 GAM28921.1 - 0.0003 19.8 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus HTH_45 PF14947.1 GAM28921.1 - 0.011 15.5 0.1 0.028 14.2 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix Enolase_C PF00113.17 GAM28921.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain CBM49 PF09478.5 GAM28922.1 - 1.7e-13 50.4 0.4 2.6e-13 49.8 0.3 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF3573 PF12097.3 GAM28922.1 - 0.036 12.6 0.4 0.15 10.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) V-ATPase_C PF03223.10 GAM28923.1 - 2e-107 359.3 9.5 2.4e-107 359.1 6.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Ank_2 PF12796.2 GAM28924.1 - 2.9e-33 114.0 3.1 2.4e-19 69.4 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM28924.1 - 2.7e-29 99.4 5.4 2.9e-09 36.2 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 GAM28924.1 - 8.7e-25 86.2 1.7 5.9e-10 39.0 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28924.1 - 2.9e-22 76.5 1.1 0.00012 21.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 GAM28924.1 - 9.9e-22 76.9 2.5 6.5e-10 39.2 0.0 4.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) ORC6 PF05460.8 GAM28924.1 - 1.5 7.7 9.0 0.058 12.4 2.0 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Exo_endo_phos PF03372.18 GAM28925.1 - 3e-14 53.5 0.0 3.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 GAM28925.1 - 7.3e-06 25.5 0.0 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Ectatomin PF06457.6 GAM28925.1 - 0.15 11.8 0.7 0.28 10.9 0.5 1.4 1 0 0 1 1 1 0 Ectatomin PIG-Y PF15159.1 GAM28926.1 - 5.7e-30 103.3 9.1 1.1e-29 102.4 6.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DisA_N PF02457.11 GAM28926.1 - 0.048 12.7 0.2 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding CDK2AP PF09806.4 GAM28926.1 - 0.067 13.4 11.5 0.087 13.0 8.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DLIC PF05783.6 GAM28926.1 - 0.081 11.5 5.4 0.076 11.6 3.1 1.2 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF4483 PF14825.1 GAM28926.1 - 0.86 9.2 9.3 1.6 8.3 6.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4483) DUF1387 PF07139.6 GAM28926.1 - 3.4 7.1 8.2 4 6.9 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF4131 PF13567.1 GAM28926.1 - 8.2 5.7 8.7 2.1 7.7 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) VPS28 PF03997.7 GAM28927.1 - 7.6e-64 214.7 4.5 9.1e-64 214.5 3.1 1.1 1 0 0 1 1 1 1 VPS28 protein UvrD_C PF13361.1 GAM28927.1 - 0.0015 18.1 2.9 0.0023 17.4 2.0 1.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Peptidase_M9_N PF08453.5 GAM28927.1 - 0.0053 16.1 1.0 0.037 13.3 0.3 2.3 1 1 1 2 2 2 1 Peptidase family M9 N-terminal RFC1 PF08519.7 GAM28927.1 - 0.0064 16.2 0.4 0.97 9.1 0.0 2.6 1 1 1 2 2 2 2 Replication factor RFC1 C terminal domain Spt4 PF06093.8 GAM28928.1 - 7.8e-26 89.7 0.4 9.8e-26 89.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger BaffR-Tall_bind PF09256.5 GAM28928.1 - 0.08 12.5 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding CsbD PF05532.7 GAM28929.1 - 0.0001 21.9 3.0 0.00024 20.6 0.1 2.3 2 0 0 2 2 2 1 CsbD-like Arm PF00514.18 GAM28930.1 - 6e-40 133.7 7.8 1.2e-09 37.6 0.1 9.5 9 1 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 GAM28930.1 - 1.4e-07 31.8 0.0 0.0025 18.2 0.0 5.0 5 1 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 GAM28930.1 - 2.7e-06 26.9 0.0 0.011 15.7 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 GAM28930.1 - 4.3e-06 26.9 0.0 0.19 12.0 0.0 4.5 1 1 3 4 4 4 3 HEAT repeats RICTOR_V PF14668.1 GAM28930.1 - 0.00057 19.7 3.2 6.1 6.8 0.0 5.4 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 Macscav_rec PF03523.8 GAM28930.1 - 0.038 13.7 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Macrophage scavenger receptor Pkinase PF00069.20 GAM28931.1 - 8.4e-71 238.1 1.1 1.4e-70 237.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28931.1 - 4.2e-48 163.6 0.0 8.3e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase U3_snoRNA_assoc PF08297.6 GAM28931.1 - 0.0012 19.0 9.6 0.0012 19.0 6.7 2.4 2 0 0 2 2 2 1 U3 snoRNA associated Kdo PF06293.9 GAM28931.1 - 0.0014 17.7 0.1 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sif PF06767.6 GAM28931.1 - 0.0073 15.1 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 Sif protein Kinase-like PF14531.1 GAM28931.1 - 0.016 14.1 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF2992 PF11208.3 GAM28931.1 - 0.91 9.4 14.1 3.8 7.4 7.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) Peptidase_S49_N PF08496.5 GAM28931.1 - 3.5 7.3 20.3 0.26 11.0 0.3 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Tox-REase-3 PF15647.1 GAM28932.1 - 0.04 13.7 0.2 0.047 13.4 0.2 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 I_LWEQ PF01608.12 GAM28932.1 - 0.22 11.4 6.8 0.23 11.3 4.7 1.3 1 0 0 1 1 1 0 I/LWEQ domain UQ_con PF00179.21 GAM28933.1 - 1.6e-46 157.1 0.1 1.9e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 GAM28933.1 - 7.5e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 GAM28933.1 - 0.00039 20.2 0.0 0.00052 19.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 GAM28933.1 - 0.077 12.7 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B APC_CDC26 PF10471.4 GAM28934.1 - 0.073 13.8 7.6 0.11 13.2 5.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Vpu PF00558.14 GAM28934.1 - 0.8 9.3 3.5 0.97 9.0 2.4 1.3 1 0 0 1 1 1 0 Vpu protein DUF3384 PF11864.3 GAM28934.1 - 1.3 7.4 17.0 1.6 7.1 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Pox_Ag35 PF03286.9 GAM28934.1 - 3.5 7.1 12.1 4.1 6.8 8.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GPCR_chapero_1 PF11904.3 GAM28934.1 - 3.7 6.6 12.7 4 6.4 8.8 1.0 1 0 0 1 1 1 0 GPCR-chaperone Trypan_glycop PF00913.14 GAM28934.1 - 4 6.2 7.7 4.3 6.1 5.3 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) LMBR1 PF04791.11 GAM28934.1 - 4.9 5.6 5.5 5 5.5 3.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein p450 PF00067.17 GAM28935.1 - 0.074 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Sen15 PF09631.5 GAM28936.1 - 1.2e-09 38.2 0.2 3.9e-09 36.6 0.2 1.8 1 1 0 1 1 1 1 Sen15 protein Ribosomal_S11 PF00411.14 GAM28936.1 - 0.023 14.8 0.2 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S11 GATA PF00320.22 GAM28937.1 - 4e-14 51.6 6.1 9.9e-14 50.4 4.2 1.7 1 0 0 1 1 1 1 GATA zinc finger HsbA PF12296.3 GAM28937.1 - 0.026 14.3 2.2 0.027 14.3 0.2 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A zf-RING_3 PF14369.1 GAM28937.1 - 0.22 11.5 2.8 0.56 10.2 1.9 1.7 1 0 0 1 1 1 0 zinc-finger RP-C_C PF11800.3 GAM28937.1 - 0.23 11.1 3.4 0.35 10.5 0.1 2.5 2 1 0 2 2 2 0 Replication protein C C-terminal region PSI PF01437.20 GAM28938.1 - 3.4e-05 23.9 11.6 6.1e-05 23.0 8.0 1.4 1 0 0 1 1 1 1 Plexin repeat CTV_P6 PF06706.6 GAM28938.1 - 0.00061 19.2 3.7 0.0013 18.1 2.5 1.5 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein CD20 PF04103.10 GAM28938.1 - 0.013 15.4 2.9 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 CD20-like family Rax2 PF12768.2 GAM28938.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Shisa PF13908.1 GAM28938.1 - 0.072 13.2 6.7 0.085 13.0 4.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 GAM28938.1 - 0.074 13.4 0.1 0.52 10.7 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain gpUL132 PF11359.3 GAM28938.1 - 0.11 11.8 0.9 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein UL132 IncA PF04156.9 GAM28938.1 - 0.19 11.3 0.0 0.19 11.3 0.0 1.4 2 0 0 2 2 2 0 IncA protein Pro-kuma_activ PF09286.6 GAM28939.1 - 7.8e-31 107.0 0.9 4.2e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 GAM28939.1 - 1.5e-09 37.4 0.7 1.5e-09 37.4 0.5 1.7 2 0 0 2 2 2 1 Subtilase family TcpA PF05946.7 GAM28939.1 - 0.0052 16.6 0.5 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 Toxin-coregulated pilus subunit TcpA LIM PF00412.17 GAM28940.1 - 1.4e-15 57.0 3.9 1.4e-15 57.0 2.7 2.0 2 0 0 2 2 2 1 LIM domain zf-CHY PF05495.7 GAM28940.1 - 0.014 15.5 4.1 0.033 14.3 2.9 1.6 1 1 0 1 1 1 0 CHY zinc finger DZR PF12773.2 GAM28940.1 - 0.083 12.7 7.7 1.4 8.7 5.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.1 GAM28940.1 - 0.12 12.1 7.3 0.2 11.3 0.7 2.5 3 1 0 3 3 2 0 zinc-RING finger domain FYVE PF01363.16 GAM28940.1 - 0.12 12.2 5.2 0.74 9.7 3.6 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 GAM28940.1 - 0.14 12.1 6.0 0.08 12.8 1.8 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 GAM28940.1 - 0.23 11.3 10.9 0.18 11.7 1.9 2.9 2 1 1 3 3 3 0 B-box zinc finger HNH PF01844.18 GAM28940.1 - 0.25 11.2 6.4 0.14 12.0 2.2 2.2 2 1 0 2 2 2 0 HNH endonuclease zf-dskA_traR PF01258.12 GAM28940.1 - 0.65 9.7 6.3 4.8 7.0 0.0 2.9 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zf-C3HC4_2 PF13923.1 GAM28940.1 - 0.67 10.0 5.4 2.3 8.3 0.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.10 GAM28940.1 - 1 9.1 0.0 1 9.1 0.0 3.2 1 1 2 3 3 3 0 BED zinc finger PHD PF00628.24 GAM28940.1 - 1.1 9.0 11.4 2.7 7.7 5.2 2.6 2 1 0 2 2 2 0 PHD-finger Ribosomal_L37ae PF01780.14 GAM28940.1 - 1.7 8.5 4.9 9.6 6.1 3.4 2.1 1 1 0 1 1 1 0 Ribosomal L37ae protein family zf-C3HC4_3 PF13920.1 GAM28940.1 - 3 7.5 9.2 1.4 8.6 1.0 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cytochrome_C7 PF14522.1 GAM28940.1 - 6 6.5 8.1 10 5.8 5.6 1.5 1 1 0 1 1 1 0 Cytochrome c7 LIM PF00412.17 GAM28941.1 - 9e-26 89.7 18.5 1.2e-12 47.7 1.9 2.4 2 0 0 2 2 2 2 LIM domain Glyco_tranf_2_4 PF13704.1 GAM28941.1 - 0.18 12.1 4.4 0.11 12.7 0.5 2.4 3 0 0 3 3 3 0 Glycosyl transferase family 2 Ribosomal_L40e PF01020.12 GAM28941.1 - 1 8.9 9.7 3.4 7.3 0.0 3.9 4 0 0 4 4 4 0 Ribosomal L40e family BRCT PF00533.21 GAM28942.1 - 6.7e-18 64.6 0.7 6.7e-10 38.9 0.0 3.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 GAM28942.1 - 3.5e-07 29.9 0.4 2e-06 27.5 0.2 2.3 2 0 0 2 2 2 1 twin BRCT domain Methyltransf_16 PF10294.4 GAM28943.1 - 1.1e-21 77.0 0.0 1.5e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 GAM28943.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 GAM28943.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.1 GAM28943.1 - 0.08 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 GAM28943.1 - 0.093 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 GAM28943.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EB PF01683.13 GAM28945.1 - 0.0068 16.4 4.1 0.0068 16.4 2.8 1.8 2 0 0 2 2 2 1 EB module EGF_2 PF07974.8 GAM28945.1 - 0.048 13.8 16.0 0.11 12.6 11.1 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.28 GAM28946.1 - 0.068 13.2 7.9 6.9 7.1 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat FNIP PF05725.7 GAM28947.1 - 2.1e-32 110.8 11.8 6.3e-10 38.8 0.0 7.7 4 2 3 8 8 8 7 FNIP Repeat F-box PF00646.28 GAM28947.1 - 0.016 14.8 0.5 0.18 11.4 0.3 2.8 2 0 0 2 2 2 0 F-box domain FNIP PF05725.7 GAM28948.1 - 6.5e-48 160.4 20.9 2.6e-13 49.6 0.3 5.7 2 2 2 5 5 5 5 FNIP Repeat DUF1769 PF08588.5 GAM28948.1 - 0.011 15.6 0.5 27 4.7 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1769) EB PF01683.13 GAM28949.1 - 0.0054 16.7 2.0 0.011 15.8 1.4 1.4 1 0 0 1 1 1 1 EB module Phage_Coat_Gp8 PF05371.7 GAM28949.1 - 0.079 12.5 2.5 0.1 12.2 0.5 2.0 2 0 0 2 2 2 0 Phage major coat protein, Gp8 EGF_2 PF07974.8 GAM28949.1 - 6.6 6.9 20.8 0.096 12.8 9.4 1.7 2 0 0 2 2 2 0 EGF-like domain Peptidase_M66 PF10462.4 GAM28950.1 - 2.8e-66 223.4 0.5 3.9e-66 222.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.1 GAM28950.1 - 0.003 17.6 0.1 0.0054 16.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 GAM28950.1 - 0.0032 17.9 0.1 0.0069 16.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 GAM28950.1 - 0.022 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 GAM28950.1 - 0.025 14.0 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 GAM28950.1 - 0.23 10.8 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Metallopep PF12044.3 GAM28950.1 - 1.8 6.9 4.8 0.22 9.9 0.5 1.4 2 0 0 2 2 2 0 Putative peptidase family EB PF01683.13 GAM28952.1 - 0.00058 19.8 3.6 0.0015 18.5 2.5 1.7 1 0 0 1 1 1 1 EB module LRR_1 PF00560.28 GAM28952.1 - 0.0011 18.7 5.0 1 9.6 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.2 GAM28952.1 - 0.0019 17.7 0.7 0.0096 15.5 0.4 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM28952.1 - 0.0025 17.5 0.2 0.01 15.5 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat EGF_2 PF07974.8 GAM28952.1 - 0.046 13.9 14.7 0.13 12.4 10.2 1.8 1 0 0 1 1 1 0 EGF-like domain CD34_antigen PF06365.7 GAM28952.1 - 0.056 13.0 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family LRR_7 PF13504.1 GAM28952.1 - 0.061 13.5 1.0 14 6.4 0.1 3.6 2 0 0 2 2 2 0 Leucine rich repeat EphA2_TM PF14575.1 GAM28952.1 - 0.23 11.8 1.9 0.44 10.9 1.3 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain eIF2A PF08662.6 GAM28955.1 - 2.2e-58 197.1 0.1 1.4e-57 194.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Caerin_1 PF07440.7 GAM28955.1 - 0.093 12.6 0.6 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 Caerin 1 protein BSD PF03909.12 GAM28956.1 - 4.2e-07 29.6 0.5 1.8e-06 27.5 0.4 2.2 1 0 0 1 1 1 1 BSD domain RCC1 PF00415.13 GAM28957.1 - 3.9e-59 196.6 8.0 1.5e-12 47.5 0.4 6.9 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 GAM28957.1 - 1.2e-34 117.2 27.6 2e-08 33.6 0.4 6.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.18 GAM28957.1 - 4.1e-32 112.0 0.0 6.5e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CBM_X PF06204.6 GAM28957.1 - 0.0001 21.6 0.3 6.1 6.3 0.0 4.3 4 0 0 4 4 4 3 Putative carbohydrate binding domain RNA_pol_A_bac PF01000.21 GAM28958.1 - 2.3e-29 101.8 0.1 4.3e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 GAM28958.1 - 4.2e-20 70.6 0.0 6.4e-20 70.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AAA PF00004.24 GAM28959.1 - 3.9e-18 65.9 0.1 2.5e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 GAM28959.1 - 1e-17 63.8 0.2 6.1e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 GAM28959.1 - 1.2e-14 54.2 0.1 2.9e-12 46.5 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 GAM28959.1 - 9e-13 47.7 0.2 1.4e-08 33.9 0.1 2.7 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 GAM28959.1 - 3.4e-07 30.4 0.1 0.0022 18.1 0.0 2.8 2 1 1 3 3 2 2 AAA domain RuvB_N PF05496.7 GAM28959.1 - 5.5e-06 25.6 0.1 2.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 GAM28959.1 - 1.5e-05 24.9 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 GAM28959.1 - 2.5e-05 24.3 0.0 0.00049 20.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 GAM28959.1 - 3.9e-05 23.3 0.0 0.00018 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 GAM28959.1 - 5.7e-05 22.7 0.1 0.00015 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 GAM28959.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 GAM28959.1 - 0.00017 21.2 0.0 0.00046 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 GAM28959.1 - 0.00019 20.4 0.0 0.00035 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 GAM28959.1 - 0.00021 20.8 0.1 0.64 9.3 0.0 2.4 1 1 1 2 2 2 2 AAA-like domain AAA_3 PF07726.6 GAM28959.1 - 0.00036 20.1 0.0 0.0011 18.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 GAM28959.1 - 0.00086 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 GAM28959.1 - 0.0015 18.8 0.0 0.005 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 GAM28959.1 - 0.0016 18.0 0.0 0.0034 16.9 0.0 1.6 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_17 PF13207.1 GAM28959.1 - 0.0016 19.2 0.0 0.0034 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 GAM28959.1 - 0.0033 17.7 0.2 0.011 16.0 0.0 1.8 1 1 1 2 2 1 1 AAA domain AAA_30 PF13604.1 GAM28959.1 - 0.0042 16.6 0.1 0.037 13.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 GAM28959.1 - 0.0045 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 GAM28959.1 - 0.0045 15.8 0.0 0.034 13.0 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_28 PF13521.1 GAM28959.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 GAM28959.1 - 0.0097 15.3 0.1 0.33 10.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 GAM28959.1 - 0.0098 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 GAM28959.1 - 0.0099 16.0 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 GAM28959.1 - 0.0099 15.5 0.0 1 9.0 0.0 3.2 1 1 1 2 2 2 1 NACHT domain AAA_33 PF13671.1 GAM28959.1 - 0.011 15.6 0.1 0.032 14.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain MobB PF03205.9 GAM28959.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 GAM28959.1 - 0.012 15.1 0.1 0.3 10.5 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.16 GAM28959.1 - 0.025 13.7 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 GAM28959.1 - 0.033 13.6 0.1 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 GAM28959.1 - 0.033 13.6 0.0 4 6.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NYD-SP12_N PF15015.1 GAM28959.1 - 0.036 12.3 0.5 0.092 10.9 0.1 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal AAA_29 PF13555.1 GAM28959.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_DnaA PF00308.13 GAM28959.1 - 0.062 12.9 0.1 0.18 11.3 0.0 2.0 2 1 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.22 GAM28959.1 - 0.075 13.3 0.1 0.58 10.4 0.0 2.3 2 1 0 2 2 2 0 ABC transporter DUF1390 PF07150.6 GAM28959.1 - 0.11 11.8 0.8 0.71 9.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) FNIP PF05725.7 GAM28960.1 - 1.1e-40 137.2 11.9 7.7e-09 35.3 0.1 10.4 8 2 2 10 10 10 9 FNIP Repeat Pkinase PF00069.20 GAM28961.1 - 1.3e-39 135.9 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM28961.1 - 1e-14 54.2 0.0 2e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM28961.1 - 0.00028 19.9 0.0 0.001 18.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 GAM28961.1 - 0.021 14.5 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 GAM28961.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 GAM28962.1 - 0.0036 16.4 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1645 PF07816.6 GAM28963.1 - 0.053 13.9 9.2 0.89 9.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) GCN5L1 PF06320.8 GAM28964.1 - 2.5e-47 159.6 1.1 3.3e-47 159.2 0.8 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) AAA_13 PF13166.1 GAM28964.1 - 0.027 12.9 2.7 0.031 12.7 1.9 1.1 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 GAM28964.1 - 1.3 8.9 5.1 3.7 7.4 0.1 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Prokineticin PF06607.6 GAM28965.1 - 0.01 15.9 1.5 0.01 15.9 1.0 2.7 2 1 0 3 3 3 0 Prokineticin FNIP PF05725.7 GAM28966.1 - 1.2e-25 89.1 18.0 6e-08 32.5 0.0 7.4 7 1 2 9 9 9 6 FNIP Repeat TerD PF02342.13 GAM28966.1 - 0.0013 18.1 0.0 0.032 13.5 0.0 2.1 2 0 0 2 2 2 1 TerD domain Peptidase_M8 PF01457.11 GAM28968.1 - 1.8e-57 194.8 0.0 2.4e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Methyltransf_11 PF08241.7 GAM28969.1 - 3.8e-13 49.7 0.0 6.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM28969.1 - 1.1e-07 31.5 0.1 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM28969.1 - 1.1e-07 32.1 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM28969.1 - 7.3e-07 29.0 0.0 1.3e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 GAM28969.1 - 5.1e-06 27.0 0.0 7.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM28969.1 - 0.00027 21.2 0.0 0.00053 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 GAM28969.1 - 0.00027 20.1 0.1 0.00051 19.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 GAM28969.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 GAM28969.1 - 0.0045 16.5 0.0 0.083 12.3 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_8 PF05148.10 GAM28969.1 - 0.0075 15.9 0.0 1.7 8.1 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_26 PF13659.1 GAM28969.1 - 0.013 15.5 0.0 0.046 13.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Acyltransferase PF01553.16 GAM28970.1 - 2e-14 53.1 0.0 3.1e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Herpes_U15 PF05613.6 GAM28970.1 - 0.91 9.8 5.0 0.41 11.0 1.2 2.0 2 0 0 2 2 2 0 Human herpesvirus U15 protein PEGSRP PF07623.6 GAM28970.1 - 1 8.7 3.6 0.6 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) RhoGEF PF00621.15 GAM28971.1 - 8.9e-40 136.4 2.3 1.8e-39 135.4 1.6 1.5 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 GAM28971.1 - 1.8e-20 72.5 7.9 3.8e-20 71.5 5.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 GAM28971.1 - 1.7e-11 44.2 0.3 5.4e-11 42.6 0.2 1.9 1 0 0 1 1 1 1 PH domain zf-DHHC PF01529.15 GAM28971.1 - 0.012 14.9 0.2 0.012 14.9 0.1 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase FYVE_2 PF02318.11 GAM28971.1 - 0.022 14.6 6.5 0.073 12.9 4.5 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrom_B558a PF05038.8 GAM28972.1 - 6e-12 45.5 10.3 1.1e-09 38.2 1.0 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit DUF308 PF03729.8 GAM28972.1 - 0.09 12.7 12.8 0.35 10.9 2.1 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF1794 PF08768.6 GAM28973.1 - 1.6e-29 102.7 0.1 1.8e-29 102.5 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Ribosomal_L6e PF01159.14 GAM28974.1 - 1.3e-16 60.7 1.2 2.3e-16 59.9 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e GTP_EFTU_D3 PF03143.12 GAM28974.1 - 0.012 15.7 0.3 0.19 11.9 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu C-terminal domain DUF2838 PF10998.3 GAM28975.1 - 2.6e-32 111.0 7.5 2.6e-32 111.0 5.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) Pho88 PF10032.4 GAM28975.1 - 0.068 12.3 2.0 0.11 11.6 1.4 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) GATA PF00320.22 GAM28976.1 - 1.7e-13 49.6 7.2 3.3e-13 48.7 5.0 1.5 1 0 0 1 1 1 1 GATA zinc finger MitMem_reg PF13012.1 GAM28976.1 - 0.031 14.3 4.6 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function KH_1 PF00013.24 GAM28977.1 - 1.9e-05 24.2 1.2 1.9e-05 24.2 0.8 1.9 2 0 0 2 2 2 1 KH domain Aminotran_5 PF00266.14 GAM28979.1 - 6.7e-39 133.6 0.0 1.3e-38 132.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 GAM28979.1 - 0.00013 20.4 0.0 0.00017 19.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 GAM28979.1 - 0.0019 17.4 0.1 0.0048 16.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 GAM28979.1 - 0.0021 16.5 0.2 0.053 11.9 0.0 2.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 GAM28979.1 - 0.0057 15.7 0.0 0.013 14.5 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family PALP PF00291.20 GAM28979.1 - 0.061 12.5 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme EB PF01683.13 GAM28980.1 - 0.0052 16.8 2.8 0.012 15.6 1.9 1.6 1 0 0 1 1 1 1 EB module EGF_2 PF07974.8 GAM28980.1 - 0.04 14.0 15.2 0.096 12.8 10.5 1.7 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.22 GAM28980.1 - 0.082 12.8 10.5 0.19 11.7 7.3 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.28 GAM28980.1 - 0.17 12.0 3.4 39 4.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat TIG PF01833.19 GAM28980.1 - 0.2 11.6 14.5 0.052 13.5 1.6 3.7 2 1 1 3 3 3 0 IPT/TIG domain DUF3827 PF12877.2 GAM28980.1 - 0.33 9.0 3.8 0.5 8.4 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SKG6 PF08693.5 GAM28980.1 - 2.2 7.6 11.3 4.7 6.6 7.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain 2OG-FeII_Oxy_2 PF13532.1 GAM28981.1 - 5e-23 81.9 0.0 5.8e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM28981.1 - 0.00037 20.7 0.0 0.00073 19.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Proteasom_PSMB PF10508.4 GAM28983.1 - 3e-05 22.4 1.4 3.9e-05 22.1 1.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 GAM28983.1 - 0.00018 21.2 2.5 0.012 15.4 0.0 3.0 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 GAM28983.1 - 0.011 14.9 2.7 0.02 14.0 1.9 1.5 1 1 0 1 1 1 0 V-ATPase subunit H HEAT PF02985.17 GAM28983.1 - 0.051 13.6 0.2 0.46 10.6 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat FAD-oxidase_C PF02913.14 GAM28984.1 - 1.1e-54 185.3 0.0 2.2e-54 184.4 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 GAM28984.1 - 1.9e-38 131.0 0.0 3.5e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HIG_1_N PF04588.8 GAM28985.1 - 0.074 12.8 2.6 0.15 11.7 0.6 2.1 2 0 0 2 2 2 0 Hypoxia induced protein conserved region LRR_4 PF12799.2 GAM28985.1 - 0.19 11.4 3.0 0.21 11.2 0.1 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM28985.1 - 0.36 11.0 2.4 1.4 9.2 0.5 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat hEGF PF12661.2 GAM28985.1 - 1.1 9.5 3.3 2.2 8.5 2.3 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF Laminin_EGF PF00053.19 GAM28985.1 - 4.1 7.4 6.7 0.46 10.4 1.5 1.7 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) TraS PF10624.4 GAM28986.1 - 2.6 7.6 6.0 4 6.9 4.1 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS PAT1 PF09770.4 GAM28986.1 - 3 5.9 11.4 3.5 5.7 7.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPC12 PF06645.8 GAM28987.1 - 1.3e-15 56.9 3.9 1.4e-15 56.8 2.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) SdpI PF13630.1 GAM28987.1 - 0.041 13.5 4.5 0.045 13.4 3.1 1.0 1 0 0 1 1 1 0 SdpI/YhfL protein family Colicin_V PF02674.11 GAM28987.1 - 0.067 13.0 5.8 0.075 12.8 4.0 1.2 1 0 0 1 1 1 0 Colicin V production protein AgrD PF05931.6 GAM28987.1 - 0.23 11.1 0.3 0.23 11.1 0.2 1.5 1 1 1 2 2 2 0 Staphylococcal AgrD protein Transgly_assoc PF04226.8 GAM28987.1 - 1 9.5 7.8 1.4 9.0 5.4 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein FUN14 PF04930.10 GAM28987.1 - 1.7 8.9 5.7 2 8.7 3.9 1.2 1 0 0 1 1 1 0 FUN14 family Ank_2 PF12796.2 GAM28988.1 - 1.8e-55 185.2 59.3 3.7e-10 39.9 0.6 8.5 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM28988.1 - 3.6e-38 128.7 27.6 0.0081 16.3 0.0 16.5 3 2 13 17 17 17 10 Ankyrin repeats (many copies) Ank_4 PF13637.1 GAM28988.1 - 1.5e-36 124.0 20.8 3.9e-05 24.0 0.1 13.1 9 4 3 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28988.1 - 5.3e-29 97.3 26.8 0.31 11.4 0.0 17.7 14 5 6 20 20 20 8 Ankyrin repeat Ank PF00023.25 GAM28988.1 - 7.2e-25 85.5 25.0 0.39 10.6 0.0 18.1 18 2 2 20 20 20 5 Ankyrin repeat RNase_P_p30 PF01876.11 GAM28988.1 - 8.8e-06 25.0 2.3 0.59 9.3 0.0 6.1 7 1 0 7 7 7 1 RNase P subunit p30 PepX_N PF09168.5 GAM28988.1 - 3.8e-05 23.9 1.1 12 6.1 0.0 6.0 3 2 4 7 7 7 1 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal ENTH PF01417.15 GAM28988.1 - 0.04 13.7 0.2 4.1 7.2 0.0 4.1 2 2 1 3 3 3 0 ENTH domain Chlorophyllase PF07224.6 GAM28988.1 - 0.11 11.2 3.2 2 7.1 0.2 3.8 3 1 0 4 4 4 0 Chlorophyllase DUF4031 PF13223.1 GAM28988.1 - 0.25 11.5 6.4 1e+02 3.1 0.1 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF4031) DUF2638 PF10937.3 GAM28989.1 - 0.038 15.0 0.1 0.069 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) Serglycin PF04360.7 GAM28989.1 - 0.09 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Serglycin PMI_typeI PF01238.16 GAM28990.1 - 3.2e-103 345.5 0.0 4e-103 345.2 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 GAM28990.1 - 0.00033 20.3 0.0 0.54 9.9 0.0 3.0 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_2 PF07883.6 GAM28990.1 - 0.002 17.5 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 GAM28990.1 - 0.015 14.9 0.0 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Cupin Cupin_1 PF00190.17 GAM28990.1 - 0.017 14.5 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Cupin AAA_13 PF13166.1 GAM28991.1 - 0.00033 19.2 33.3 0.00033 19.2 23.1 5.3 1 1 4 5 5 5 4 AAA domain Filament PF00038.16 GAM28991.1 - 0.0013 18.2 146.1 0.037 13.5 25.1 5.4 1 1 3 4 4 4 3 Intermediate filament protein Reo_sigmaC PF04582.7 GAM28991.1 - 0.0025 17.0 54.6 0.056 12.6 4.0 6.0 1 1 6 7 7 7 4 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 GAM28991.1 - 0.0069 16.1 2.9 0.0069 16.1 2.0 13.3 5 3 9 14 14 14 1 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 GAM28991.1 - 0.0072 16.6 0.6 0.0072 16.6 0.4 12.0 2 1 9 13 13 13 4 SlyX Myosin_tail_1 PF01576.14 GAM28991.1 - 0.066 10.9 161.3 0.0062 14.3 40.4 4.4 1 1 2 3 3 3 0 Myosin tail UCH PF00443.24 GAM28993.1 - 7.6e-56 189.1 3.6 4.4e-55 186.6 2.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 GAM28993.1 - 1.2e-15 57.7 9.1 1.2e-15 57.7 6.3 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4428 PF14471.1 GAM28993.1 - 0.00012 21.7 2.1 0.22 11.3 0.3 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.8 GAM28993.1 - 0.024 14.1 1.6 4.6 6.8 0.0 3.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger Ribosomal_L2_C PF03947.13 GAM28994.1 - 2.7e-41 140.4 1.7 4.2e-41 139.8 1.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 GAM28994.1 - 3.1e-18 65.5 0.0 7.9e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain zf-C2H2_jaz PF12171.3 GAM28995.1 - 7.3e-05 22.7 6.4 0.062 13.4 0.6 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 GAM28995.1 - 0.0017 18.4 2.7 0.11 12.5 0.5 2.3 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 GAM28995.1 - 0.0021 18.2 4.2 0.26 11.7 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 GAM28995.1 - 0.0091 16.2 4.6 0.57 10.6 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.17 GAM28995.1 - 0.11 12.5 2.8 0.21 11.6 1.9 1.4 1 0 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.1 GAM28995.1 - 1.1 9.2 5.1 0.7 9.8 0.1 2.2 1 1 1 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.9 GAM28995.1 - 1.4 8.6 5.7 3.8 7.2 0.3 2.4 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 GAM28995.1 - 2.1 8.7 7.1 7.9 6.9 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain ABC1 PF03109.11 GAM28996.1 - 2.4e-29 101.7 0.0 7.8e-29 100.0 0.0 1.9 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 GAM28996.1 - 0.04 13.6 0.1 0.04 13.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1682 PF07946.9 GAM28996.1 - 0.17 10.6 6.3 0.28 9.9 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RasGEF PF00617.14 GAM28997.1 - 7.2e-66 221.5 3.0 2e-65 220.0 2.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 GAM28997.1 - 7.1e-21 74.2 0.6 7.1e-21 74.2 0.4 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif CH PF00307.26 GAM28997.1 - 8.5e-08 32.2 0.3 3.7e-07 30.1 0.2 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 GAM28997.1 - 0.0019 18.2 5.2 0.0021 18.1 0.0 3.0 3 0 0 3 3 3 1 CDC24 Calponin LRR_8 PF13855.1 GAM28998.1 - 1.8e-15 56.4 20.4 9e-06 25.3 0.2 6.0 3 2 2 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 GAM28998.1 - 2.5e-15 54.7 23.5 0.055 13.5 0.0 10.5 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.2 GAM28998.1 - 2.1e-13 49.5 22.2 1.5e-05 24.4 0.0 6.5 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM28998.1 - 4.7e-09 35.0 20.2 1 9.6 0.0 10.1 9 1 1 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 GAM28998.1 - 3.6e-08 32.3 22.5 2.4 8.7 0.1 9.3 10 0 0 10 10 10 4 Leucine rich repeat Ank_2 PF12796.2 GAM28999.1 - 8.3e-53 176.6 17.5 5.9e-08 32.9 0.0 7.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM28999.1 - 1.2e-30 105.3 10.8 3.4e-05 24.2 0.0 10.4 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM28999.1 - 4.5e-29 99.8 14.7 0.01 16.0 0.1 13.6 2 2 12 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM28999.1 - 2.9e-22 76.5 8.9 0.026 14.7 0.0 12.5 7 3 6 13 13 13 6 Ankyrin repeat Ank PF00023.25 GAM28999.1 - 1.3e-15 56.3 14.2 0.61 9.9 0.0 12.3 13 1 1 14 14 14 5 Ankyrin repeat AAA PF00004.24 GAM29000.1 - 9.4e-81 268.5 0.0 2.5e-41 140.9 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 GAM29000.1 - 1.1e-14 54.7 0.0 8.8e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 GAM29000.1 - 1.6e-10 41.2 0.1 0.00032 20.7 0.0 3.4 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 GAM29000.1 - 2.3e-10 40.3 0.1 0.00064 19.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 GAM29000.1 - 4.1e-10 39.8 0.7 0.00061 19.9 0.1 4.3 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.1 GAM29000.1 - 3.3e-08 33.4 0.0 0.0066 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM29000.1 - 3.1e-07 31.2 0.0 0.014 16.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 GAM29000.1 - 7.5e-07 28.4 0.0 0.00065 18.8 0.0 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 GAM29000.1 - 7.9e-07 28.7 0.1 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 GAM29000.1 - 1.8e-06 27.6 0.6 0.34 10.5 0.0 3.8 4 0 0 4 4 4 2 NACHT domain AAA_25 PF13481.1 GAM29000.1 - 3.3e-06 26.6 1.3 0.67 9.3 0.1 3.9 3 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 GAM29000.1 - 4e-06 25.8 0.0 0.0038 15.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_3 PF07726.6 GAM29000.1 - 7.4e-06 25.5 0.0 0.076 12.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 GAM29000.1 - 9.4e-06 25.5 0.0 0.086 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 GAM29000.1 - 1e-05 25.6 0.1 0.29 11.3 0.0 3.1 3 0 0 3 3 2 2 RNA helicase ABC_tran PF00005.22 GAM29000.1 - 4.9e-05 23.6 0.1 0.48 10.7 0.0 3.0 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.13 GAM29000.1 - 5.4e-05 22.8 0.0 0.045 13.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 GAM29000.1 - 0.00014 20.8 0.0 0.15 10.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) UPF0079 PF02367.12 GAM29000.1 - 0.00015 21.4 0.3 0.41 10.2 0.0 3.4 3 1 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 GAM29000.1 - 0.00073 19.2 0.8 0.51 10.0 0.0 3.5 2 2 1 3 3 3 1 NTPase Zeta_toxin PF06414.7 GAM29000.1 - 0.0011 18.1 0.1 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 GAM29000.1 - 0.0018 17.7 0.3 0.44 9.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein MCM PF00493.18 GAM29000.1 - 0.0019 17.0 0.0 0.91 8.2 0.0 2.5 2 0 0 2 2 2 1 MCM2/3/5 family AAA_11 PF13086.1 GAM29000.1 - 0.002 17.7 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 GAM29000.1 - 0.0027 17.7 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 GAM29000.1 - 0.0029 16.3 0.0 0.0097 14.6 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 GAM29000.1 - 0.0036 17.0 0.0 1.7 8.3 0.0 3.7 3 2 1 4 4 4 1 Archaeal ATPase AAA_28 PF13521.1 GAM29000.1 - 0.0048 16.8 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 GAM29000.1 - 0.0073 15.9 0.0 0.72 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 GAM29000.1 - 0.0085 15.2 0.6 3.5 6.7 0.0 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 GAM29000.1 - 0.011 15.4 0.0 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.21 GAM29000.1 - 0.012 15.0 0.1 1.7 8.0 0.0 3.5 2 2 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 GAM29000.1 - 0.017 15.4 0.3 5.4 7.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 GAM29000.1 - 0.022 14.1 0.2 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AFG1_ATPase PF03969.11 GAM29000.1 - 0.049 12.4 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase NB-ARC PF00931.17 GAM29000.1 - 0.087 11.6 0.0 0.46 9.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 GAM29000.1 - 0.1 12.0 0.0 5.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 GAM29000.1 - 0.17 10.9 0.8 15 4.6 0.1 3.3 3 1 1 4 4 4 0 KaiC zf-ribbon_3 PF13248.1 GAM29001.1 - 0.0067 15.6 2.8 0.014 14.5 1.9 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 GAM29001.1 - 0.067 13.0 3.6 0.16 11.8 2.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 GAM29001.1 - 0.35 10.7 3.4 0.89 9.4 2.4 1.8 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L27 PF01016.14 GAM29002.1 - 1.3e-35 120.9 1.3 1.8e-35 120.5 0.9 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DUF2233 PF09992.4 GAM29002.1 - 0.016 15.1 0.5 0.79 9.7 0.1 2.1 1 1 1 2 2 2 0 Predicted periplasmic protein (DUF2233) GST_C PF00043.20 GAM29003.1 - 1.2e-11 44.4 0.1 2.5e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM29003.1 - 1.3e-08 34.8 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM29003.1 - 2.6e-08 33.7 0.0 5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM29003.1 - 3.8e-08 33.1 0.8 9.7e-08 31.7 0.3 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM29003.1 - 4.6e-08 33.1 0.0 9.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM29003.1 - 8.7e-06 26.1 0.1 1.4e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.1 GAM29004.1 - 1.8e-12 47.4 0.1 5.9e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM29004.1 - 2.8e-12 46.8 0.0 5.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 GAM29004.1 - 1.8e-11 43.2 0.0 0.00015 21.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.24 GAM29004.1 - 3.5e-11 43.2 0.0 9.1e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.1 GAM29004.1 - 2.4e-09 37.1 0.1 2.6e-06 27.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29004.1 - 2.6e-07 30.2 0.0 0.0034 17.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PH_11 PF15413.1 GAM29004.1 - 1.4e-05 25.3 0.7 0.00051 20.2 0.5 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3447 PF11929.3 GAM29004.1 - 0.035 13.8 2.6 0.043 13.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) WD40 PF00400.27 GAM29005.1 - 2.6e-12 46.0 12.1 0.042 13.7 0.5 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Acyl-CoA_dh_M PF02770.14 GAM29006.1 - 1.6e-11 43.5 0.2 3.5e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 GAM29006.1 - 1.6e-10 41.3 0.1 3.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 GAM29006.1 - 1.7e-05 24.2 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_2 PF08028.6 GAM29006.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Sybindin PF04099.7 GAM29007.1 - 4e-41 140.0 1.5 4.5e-41 139.8 1.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 GAM29007.1 - 1e-06 28.6 0.5 1.1e-06 28.5 0.4 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region zf-RING_2 PF13639.1 GAM29008.1 - 3.8e-12 45.8 9.5 7.5e-12 44.8 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 GAM29008.1 - 1.3e-11 43.9 6.6 2e-11 43.3 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM29008.1 - 1.7e-11 43.9 10.2 3e-11 43.1 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM29008.1 - 4.1e-09 35.9 9.4 7.4e-09 35.1 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 GAM29008.1 - 4.4e-08 33.1 8.1 1.5e-07 31.4 5.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 GAM29008.1 - 9.2e-08 31.6 7.5 1.5e-07 30.9 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 GAM29008.1 - 8e-07 28.6 6.2 1.7e-06 27.5 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 GAM29008.1 - 4.2e-05 23.3 9.4 7.7e-05 22.4 6.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 GAM29008.1 - 0.0013 18.4 4.1 0.0026 17.4 2.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 GAM29008.1 - 0.0053 16.5 5.5 0.056 13.2 3.3 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 GAM29008.1 - 0.052 13.1 3.2 0.14 11.7 2.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 GAM29008.1 - 0.089 12.3 4.2 0.18 11.3 2.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 GAM29008.1 - 0.25 10.9 7.3 0.66 9.6 5.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Nicastrin PF05450.10 GAM29008.1 - 0.28 10.3 6.1 0.083 12.1 2.2 1.6 2 0 0 2 2 2 0 Nicastrin zf-P11 PF03854.9 GAM29008.1 - 1.1 8.7 4.9 16 5.0 3.8 2.2 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.2 GAM29008.1 - 1.6 8.5 5.2 4.1 7.2 3.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Nitrate_red_gam PF02665.9 GAM29009.1 - 0.0062 15.9 0.1 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF3816 PF12822.2 GAM29009.1 - 0.015 15.2 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) Epiglycanin_C PF14654.1 GAM29009.1 - 0.051 13.5 0.2 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Chlam_PMP PF02415.12 GAM29009.1 - 0.41 11.0 0.1 0.41 11.0 0.1 7.4 9 1 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Serinc PF03348.10 GAM29010.1 - 1.3e-94 317.3 8.8 1.5e-94 317.1 6.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Orbi_NS3 PF01616.11 GAM29010.1 - 0.034 13.1 0.5 0.28 10.1 0.2 2.3 2 1 0 2 2 2 0 Orbivirus NS3 7TMR-DISM_7TM PF07695.6 GAM29010.1 - 0.43 10.2 26.2 0.059 13.0 14.2 2.3 2 1 1 3 3 3 0 7TM diverse intracellular signalling Peptidase_M50B PF13398.1 GAM29010.1 - 0.94 8.8 13.1 0.06 12.7 3.4 2.8 1 1 1 2 2 2 0 Peptidase M50B-like DUF2871 PF11070.3 GAM29010.1 - 4.6 7.4 13.2 0.25 11.5 3.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2871) DUF3535 PF12054.3 GAM29011.1 - 2e-72 244.2 2.2 2e-72 244.2 1.5 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 GAM29011.1 - 8.5e-71 238.1 0.0 2.4e-70 236.6 0.0 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 GAM29011.1 - 7.3e-14 50.5 3.4 0.043 13.9 0.0 9.9 9 0 0 9 9 9 2 HEAT repeat Helicase_C PF00271.26 GAM29011.1 - 1.9e-13 50.0 0.0 1.7e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 GAM29011.1 - 6.2e-12 45.6 0.0 0.017 15.3 0.0 6.3 4 2 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.2 GAM29011.1 - 5.9e-09 36.1 0.2 0.0022 18.3 0.0 4.0 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 GAM29011.1 - 8.8e-08 32.4 9.5 0.00056 20.3 0.0 7.2 8 1 1 9 9 9 2 HEAT-like repeat Cnd1 PF12717.2 GAM29011.1 - 0.12 12.2 9.4 2.7 7.8 0.0 4.9 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Mak16 PF04874.9 GAM29011.1 - 0.45 10.6 5.2 4.9 7.2 2.4 2.7 1 1 1 2 2 2 0 Mak16 protein C-terminal region Peptidase_S9_N PF02897.10 GAM29013.1 - 2.5e-106 355.7 1.8 3e-106 355.4 1.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 GAM29013.1 - 1.7e-62 210.4 0.5 3.6e-62 209.3 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 GAM29013.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold 2OG-FeII_Oxy_3 PF13640.1 GAM29014.1 - 9.3e-10 38.9 0.0 1.5e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 GAM29014.1 - 1.1e-09 37.7 0.2 2.4e-09 36.6 0.1 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 GAM29014.1 - 0.00066 18.5 0.0 0.00092 18.0 0.0 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein EMG1 PF03587.9 GAM29015.1 - 1.9e-87 291.7 0.0 2.5e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ETX_MTX2 PF03318.8 GAM29015.1 - 0.0049 16.4 1.8 0.0077 15.8 1.3 1.3 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Pro_isomerase PF00160.16 GAM29016.1 - 4.1e-49 166.7 0.5 4.6e-49 166.5 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3439 PF11921.3 GAM29017.1 - 0.24 11.1 17.9 1.5 8.5 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) V-ATPase_H_N PF03224.9 GAM29018.1 - 2e-59 201.2 0.2 4.7e-59 200.0 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 GAM29018.1 - 3.7e-46 155.8 3.9 1.4e-45 154.0 0.6 2.6 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.8 GAM29018.1 - 1.1e-05 24.6 0.4 0.0004 19.5 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 GAM29018.1 - 0.013 15.7 0.0 0.14 12.4 0.0 2.6 4 0 0 4 4 4 0 HEAT repeats Arm PF00514.18 GAM29018.1 - 0.064 13.0 0.1 11 5.9 0.0 3.9 3 1 2 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 GAM29018.1 - 0.14 12.2 0.0 0.55 10.4 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat RhoGAP PF00620.22 GAM29021.1 - 2.1e-29 102.0 0.2 1.1e-27 96.5 0.1 2.2 2 0 0 2 2 2 2 RhoGAP domain p450 PF00067.17 GAM29023.1 - 2.7e-67 227.3 0.0 3.3e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Presenilin PF01080.12 GAM29023.1 - 0.04 12.7 1.0 0.057 12.2 0.7 1.2 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.7 GAM29024.1 - 4.6e-13 48.9 14.6 5.7e-11 42.1 2.9 2.2 2 0 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 GAM29024.1 - 4.3e-12 45.8 22.0 3.8e-07 30.0 4.5 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM29024.1 - 7.7e-11 41.6 18.9 3.3e-06 26.8 5.7 3.2 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 GAM29024.1 - 1.1e-07 31.6 21.6 7.5e-06 25.7 2.6 2.9 3 1 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 GAM29024.1 - 4.6e-06 26.1 23.7 3.2e-05 23.4 3.6 3.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM29024.1 - 1.8e-05 24.3 5.7 1.8e-05 24.3 4.0 3.1 2 0 0 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.9 GAM29024.1 - 2.1e-05 23.8 2.7 0.0012 18.2 0.2 2.8 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C3HC4_3 PF13920.1 GAM29024.1 - 0.00012 21.7 25.2 0.0012 18.5 6.3 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM29024.1 - 0.00062 19.4 12.2 0.00062 19.4 8.4 3.9 2 2 2 4 4 4 1 zinc-RING finger domain zf-RING_6 PF14835.1 GAM29024.1 - 0.0071 16.1 8.9 0.19 11.5 0.4 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein FYVE PF01363.16 GAM29024.1 - 0.0072 16.1 10.0 0.0072 16.1 6.9 2.6 2 1 0 2 2 2 1 FYVE zinc finger DUF581 PF04570.9 GAM29024.1 - 0.17 11.1 0.1 0.17 11.1 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF581) zf-Nse PF11789.3 GAM29024.1 - 0.55 9.7 12.3 0.72 9.4 1.6 2.6 3 0 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 GAM29024.1 - 0.61 9.9 8.2 0.056 13.2 1.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_2 PF12674.2 GAM29024.1 - 0.92 9.8 9.5 1.1 9.6 2.2 2.9 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-C2H2_jaz PF12171.3 GAM29024.1 - 2.7 8.2 13.0 2.1 8.6 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-rbx1 PF12678.2 GAM29024.1 - 2.7 8.1 18.9 1.3 9.1 4.4 3.5 2 2 1 3 3 3 0 RING-H2 zinc finger DUF204 PF02659.10 GAM29025.1 - 2.1 8.5 6.8 1.5 9.0 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF EGF_2 PF07974.8 GAM29027.1 - 1.8e-05 24.7 13.5 3.4e-05 23.8 9.3 1.5 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.22 GAM29027.1 - 0.0092 15.9 6.5 0.017 15.0 4.5 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 GAM29027.1 - 0.1 12.6 3.2 0.21 11.7 2.2 1.4 1 0 0 1 1 1 0 EB module Pkinase_Tyr PF07714.12 GAM29028.1 - 6.5e-53 179.4 0.0 1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM29028.1 - 3.5e-49 167.2 0.0 6e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 GAM29028.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LLC1 PF14945.1 GAM29028.1 - 0.095 13.0 2.8 0.37 11.0 1.9 2.1 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Menin PF05053.8 GAM29028.1 - 2.4 6.2 6.9 3.8 5.5 4.8 1.3 1 0 0 1 1 1 0 Menin ALMT PF11744.3 GAM29030.1 - 3.1e-36 124.8 6.6 6.9e-36 123.7 4.6 1.6 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.1 GAM29030.1 - 2.2e-17 63.1 16.9 2.2e-17 63.1 11.7 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 GAM29030.1 - 4.1e-13 48.6 12.0 4.1e-13 48.6 8.3 1.6 2 0 0 2 2 2 1 Fusaric acid resistance protein family NDUF_B12 PF08122.7 GAM29031.1 - 7.4e-07 28.8 0.0 8.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Alba PF01918.16 GAM29032.1 - 0.00084 18.8 1.0 0.0012 18.3 0.1 1.8 2 0 0 2 2 2 1 Alba PSP1 PF04468.7 GAM29032.1 - 0.079 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 PSP1 C-terminal conserved region DUF3203 PF11462.3 GAM29032.1 - 0.14 12.0 0.4 2.9 7.8 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3203) UbiA PF01040.13 GAM29033.1 - 3.2e-32 111.7 18.3 4.1e-32 111.4 12.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PARP PF00644.15 GAM29034.1 - 4.7e-14 52.2 2.5 1.3e-12 47.5 0.3 3.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain zf-C3Hc3H PF13891.1 GAM29034.1 - 0.51 10.4 17.9 1.9 8.5 0.2 4.6 4 0 0 4 4 4 0 Potential DNA-binding domain zf-TRM13_CCCH PF11722.3 GAM29034.1 - 8.1 5.9 8.7 11 5.5 0.1 3.6 3 0 0 3 3 3 0 CCCH zinc finger in TRM13 protein DUF1768 PF08719.6 GAM29035.1 - 1.6e-40 138.3 0.0 2.4e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HAT PF02184.11 GAM29035.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat PARP PF00644.15 GAM29037.1 - 1.2e-07 31.3 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.11 GAM29037.1 - 0.029 13.6 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family WAK_assoc PF14380.1 GAM29038.1 - 0.076 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal zf-BED PF02892.10 GAM29038.1 - 0.11 12.3 2.8 0.33 10.7 2.0 1.8 1 0 0 1 1 1 0 BED zinc finger TFIIA PF03153.8 GAM29038.1 - 0.89 9.3 8.6 0.88 9.4 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.16 GAM29039.1 - 3.6e-12 46.0 5.4 7.9e-12 44.9 3.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 GAM29039.1 - 2.6e-11 43.1 3.4 2.6e-11 43.1 2.4 2.9 3 0 0 3 3 3 2 Basic region leucine zipper DUF737 PF05300.6 GAM29039.1 - 0.0016 18.4 10.2 0.0016 18.4 7.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF737) bZIP_Maf PF03131.12 GAM29039.1 - 0.0036 17.5 5.0 0.0036 17.5 3.5 2.9 2 1 1 3 3 3 1 bZIP Maf transcription factor Adap_comp_sub PF00928.16 GAM29040.1 - 9.4e-74 247.8 0.3 1.1e-73 247.5 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 GAM29040.1 - 0.00053 19.7 0.2 0.0012 18.5 0.1 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 GAM29041.1 - 7.8e-60 201.7 2.5 1.1e-59 201.2 1.7 1.2 1 0 0 1 1 1 1 Maf1 regulator PCNA_N PF00705.13 GAM29041.1 - 0.036 13.5 0.7 0.14 11.6 0.3 2.0 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain RabGAP-TBC PF00566.13 GAM29042.1 - 8.2e-45 152.9 0.5 1.7e-44 151.8 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FNIP PF05725.7 GAM29044.1 - 1.7e-48 162.2 11.2 2.4e-13 49.7 0.1 8.1 4 3 2 8 8 8 7 FNIP Repeat APC_CDC26 PF10471.4 GAM29045.1 - 7.6 7.3 22.8 5.1 7.9 3.7 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 EMP24_GP25L PF01105.19 GAM29046.1 - 2.1e-57 193.7 0.0 2.5e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3539 PF12058.3 GAM29046.1 - 0.041 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) G-patch PF01585.18 GAM29047.1 - 5.6e-12 45.2 2.5 1.6e-11 43.7 1.7 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM29047.1 - 0.00017 21.3 1.2 0.00017 21.3 0.8 4.7 3 1 1 4 4 4 1 DExH-box splicing factor binding site Utp14 PF04615.8 GAM29047.1 - 0.33 9.0 58.7 0.43 8.6 40.7 1.2 1 0 0 1 1 1 0 Utp14 protein Ribosomal_S4 PF00163.14 GAM29049.1 - 6.8e-08 32.7 0.2 4.5e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 GAM29049.1 - 8.8e-07 28.2 0.0 2.3e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain LKAAEAR PF15478.1 GAM29049.1 - 0.0081 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif Ank_5 PF13857.1 GAM29050.1 - 5.9e-13 48.5 0.1 1.2e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 GAM29050.1 - 4.9e-10 39.6 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM29050.1 - 1.4e-07 31.7 0.1 3.3e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 GAM29050.1 - 4.4e-07 29.3 0.1 1e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 GAM29050.1 - 4.5e-05 23.3 0.2 0.0007 19.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Pex14_N PF04695.8 GAM29050.1 - 0.015 15.3 3.0 0.015 15.3 2.1 3.1 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GST_C PF00043.20 GAM29051.1 - 4.9e-12 45.6 0.1 8.7e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM29051.1 - 2.8e-10 40.2 0.0 5.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM29051.1 - 1.8e-09 37.3 0.5 4e-09 36.2 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 GAM29051.1 - 7.1e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 GAM29051.1 - 1.5e-08 34.7 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM29051.1 - 8.9e-08 32.5 0.1 1.5e-07 31.7 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Exo_endo_phos PF03372.18 GAM29053.1 - 5.8e-11 42.7 0.0 9.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Peptidase_M8 PF01457.11 GAM29054.1 - 3.7e-58 197.1 2.8 5.5e-58 196.5 1.9 1.2 1 0 0 1 1 1 1 Leishmanolysin TMEM154 PF15102.1 GAM29054.1 - 1.2 8.8 6.1 0.43 10.2 1.3 2.2 2 0 0 2 2 2 0 TMEM154 protein family UQ_con PF00179.21 GAM29055.1 - 2.5e-34 117.7 0.6 2.1e-27 95.2 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 GAM29055.1 - 1.9e-05 24.5 0.0 0.0025 17.6 0.0 2.7 2 1 0 2 2 2 1 RWD domain UEV PF05743.8 GAM29055.1 - 0.00051 19.7 0.4 0.0035 17.0 0.0 2.5 2 1 0 2 2 2 1 UEV domain Sigma_reg_C PF13791.1 GAM29055.1 - 0.27 11.2 8.5 0.21 11.5 4.0 2.3 1 1 1 2 2 2 0 Sigma factor regulator C-terminal DBC1 PF14443.1 GAM29056.1 - 3.1e-37 126.9 0.0 3.1e-37 126.9 0.0 2.9 4 0 0 4 4 4 1 DBC1 IP_trans PF02121.13 GAM29057.1 - 7.6e-101 336.5 0.9 8.7e-101 336.3 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein MATH PF00917.21 GAM29058.1 - 1.4e-43 147.9 32.5 5.6e-16 58.8 1.1 4.7 5 0 0 5 5 5 4 MATH domain GRP PF07172.6 GAM29058.1 - 0.36 11.3 18.9 0.71 10.3 13.1 1.4 1 0 0 1 1 1 0 Glycine rich protein family Med15 PF09606.5 GAM29058.1 - 1.5 6.9 30.3 2.1 6.4 21.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 GAM29058.1 - 8.2 5.6 10.0 14 4.9 6.9 1.3 1 0 0 1 1 1 0 FCP1, C-terminal BAF1_ABF1 PF04684.8 GAM29058.1 - 9.4 4.9 22.7 16 4.1 15.7 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PIG-S PF10510.4 GAM29059.1 - 8.6e-114 381.0 16.7 3.1e-106 356.1 7.6 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein DUF4398 PF14346.1 GAM29059.1 - 0.021 14.8 1.1 0.021 14.8 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) VASP_tetra PF08776.6 GAM29060.1 - 0.73 9.1 8.0 1.3 8.4 5.5 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain Pkinase PF00069.20 GAM29061.1 - 1.3e-53 181.7 0.0 4.6e-53 180.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29061.1 - 3e-53 180.5 0.0 7.1e-53 179.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 GAM29061.1 - 1.2e-29 102.4 3.9 4e-11 43.1 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 GAM29061.1 - 9.1e-26 88.3 3.5 1.6e-06 27.6 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 GAM29061.1 - 1.3e-22 79.7 5.8 9.3e-08 32.3 0.0 5.4 2 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29061.1 - 5.6e-19 66.3 2.9 0.00032 20.6 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 GAM29061.1 - 2.6e-18 65.6 4.0 2.4e-05 24.3 0.1 5.0 2 2 3 5 5 5 3 Ankyrin repeats (many copies) GRAM PF02893.15 GAM29061.1 - 2.2e-13 49.4 0.1 5.3e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 GRAM domain C1_1 PF00130.17 GAM29061.1 - 7.2e-09 35.2 8.9 1.8e-08 33.9 6.1 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 GAM29061.1 - 0.0008 19.0 4.9 0.0019 17.9 3.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 bPH_3 PF14470.1 GAM29061.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial PH domain APH PF01636.18 GAM29061.1 - 0.031 13.9 0.0 0.36 10.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RasGEF PF00617.14 GAM29062.1 - 7.3e-46 156.2 2.8 7.3e-46 156.2 1.9 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAM29062.1 - 6.1e-19 68.0 3.1 9.8e-19 67.3 0.8 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Rpr2 PF04032.11 GAM29062.1 - 0.029 14.2 0.0 0.096 12.5 0.0 1.9 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Coronavirus_5 PF05528.6 GAM29062.1 - 0.056 13.2 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein EntA_Immun PF08951.5 GAM29062.1 - 0.75 9.9 7.5 0.13 12.4 1.1 2.9 2 0 0 2 2 2 0 Enterocin A Immunity PUF PF00806.14 GAM29063.1 - 3.2e-31 105.0 16.2 4.1e-05 22.8 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Tenui_NCP PF04876.7 GAM29063.1 - 0.0022 17.5 0.2 0.0094 15.5 0.1 2.1 1 1 0 1 1 1 1 Tenuivirus major non-capsid protein MetJ PF01340.15 GAM29063.1 - 0.0074 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Met Apo-repressor, MetJ Cupin_8 PF13621.1 GAM29066.1 - 8.5e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain WD40 PF00400.27 GAM29067.1 - 5e-16 57.8 18.1 8.5e-07 28.6 0.3 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat RWD PF05773.17 GAM29067.1 - 0.00016 21.5 0.9 0.00016 21.5 0.6 2.1 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.1 GAM29067.1 - 1.9 8.3 13.0 0.013 15.2 2.5 2.3 2 0 0 2 2 2 0 Ring finger domain DUF515 PF04415.7 GAM29068.1 - 1.3 7.1 19.7 1.9 6.6 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mucin PF01456.12 GAM29068.1 - 5.5 6.7 49.6 0.34 10.6 28.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_transf_49 PF13896.1 GAM29069.1 - 2.4e-45 154.9 0.4 1.2e-37 129.7 0.1 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM29069.1 - 8.8e-07 28.2 0.7 2.8e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM29069.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 DSPc PF00782.15 GAM29070.1 - 5.2e-18 64.9 0.0 6.4e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 GAM29070.1 - 9.4e-05 21.8 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 GAM29070.1 - 0.0011 18.9 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 GAM29070.1 - 0.005 17.1 0.0 0.0067 16.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 GAM29070.1 - 0.019 14.4 0.2 0.031 13.7 0.0 1.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Glyco_transf_10 PF00852.14 GAM29071.1 - 2.3e-45 154.6 0.8 3.1e-45 154.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Phage_hub_GP28 PF11110.3 GAM29071.1 - 0.089 12.4 0.9 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 Baseplate hub distal subunit Glyco_transf_10 PF00852.14 GAM29072.1 - 1.9e-51 174.7 2.3 2.4e-51 174.3 1.6 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Ras PF00071.17 GAM29074.1 - 7.1e-58 194.5 0.8 8.4e-58 194.3 0.6 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 GAM29074.1 - 9.5e-21 73.8 0.3 1.1e-20 73.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 GAM29074.1 - 3.2e-18 66.3 0.1 4.9e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 GAM29074.1 - 9.1e-07 28.2 0.1 1.1e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM29074.1 - 1.3e-06 28.0 0.1 6.7e-05 22.3 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 GAM29074.1 - 1.3e-05 24.5 1.0 3.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 GAM29074.1 - 0.00098 19.0 0.0 0.0018 18.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 GAM29074.1 - 0.0061 16.0 0.0 0.053 13.0 0.0 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 GAM29074.1 - 0.0095 14.6 0.1 0.2 10.2 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.1 GAM29074.1 - 0.012 15.5 0.1 0.3 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 GAM29074.1 - 0.022 14.3 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 GAM29074.1 - 0.044 13.9 0.0 0.41 10.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 GAM29074.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 GAM29074.1 - 0.076 12.7 0.2 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Acyltransferase PF01553.16 GAM29075.1 - 2.2e-21 75.6 0.0 3.3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase RNase_P_Rpp14 PF01900.14 GAM29076.1 - 8.3e-17 61.0 0.0 1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family BNIP2 PF12496.3 GAM29076.1 - 0.041 14.0 2.6 0.054 13.6 1.8 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DCP1 PF06058.8 GAM29077.1 - 2.4e-38 130.9 1.6 3.8e-38 130.3 1.1 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Zip PF02535.17 GAM29077.1 - 0.17 10.8 5.1 0.23 10.4 3.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 GAM29077.1 - 0.75 7.9 54.5 1.2 7.2 37.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gaa1 PF04114.9 GAM29078.1 - 3e-26 92.2 21.3 6e-25 87.9 14.8 2.6 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component CDC45 PF02724.9 GAM29078.1 - 0.074 11.0 1.2 0.1 10.6 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein LIM PF00412.17 GAM29079.1 - 1.8e-11 43.8 5.8 2.8e-11 43.2 4.0 1.3 1 0 0 1 1 1 1 LIM domain DNA_RNApol_7kD PF03604.8 GAM29079.1 - 0.052 13.0 0.6 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Voltage_CLC PF00654.15 GAM29080.1 - 6.2e-95 318.2 27.4 6.5e-95 318.1 16.7 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAM29080.1 - 3.4e-14 52.3 0.2 9.6e-06 25.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain UCR_Fe-S_N PF10399.4 GAM29080.1 - 0.0052 15.9 1.1 0.017 14.2 0.7 1.9 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 GAM29080.1 - 0.0059 16.5 1.7 0.0059 16.5 1.2 3.0 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence DUF2418 PF10332.4 GAM29080.1 - 0.42 10.9 0.1 0.42 10.9 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2418) Glyco_hydro_18 PF00704.23 GAM29081.1 - 1.1e-21 77.6 3.2 1.7e-21 77.0 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_transf_49 PF13896.1 GAM29082.1 - 4.7e-46 157.3 1.6 1.5e-37 129.4 0.7 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM29082.1 - 3.1e-07 29.7 0.1 3.1e-07 29.7 0.1 1.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 GAM29082.1 - 0.001 18.7 0.0 0.0025 17.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 GAM29082.1 - 0.027 14.2 0.3 0.097 12.4 0.2 1.8 1 1 0 1 1 1 0 Glycosyltransferase like family 2 RWP-RK PF02042.10 GAM29083.1 - 0.0079 16.0 0.2 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain CRAL_TRIO PF00650.15 GAM29084.1 - 5.4e-35 120.2 0.1 1.4e-34 118.8 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 GAM29084.1 - 5e-07 30.0 8.2 0.0003 21.0 0.3 3.3 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.10 GAM29084.1 - 7.4e-07 29.2 1.4 2e-06 27.8 1.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 GAM29084.1 - 4.3e-06 26.7 0.1 1.3e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF3275 PF11679.3 GAM29084.1 - 0.052 13.1 3.3 0.095 12.3 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Glyco_transf_49 PF13896.1 GAM29085.1 - 1.6e-50 171.9 4.5 1.2e-43 149.4 1.7 2.8 1 1 2 3 3 3 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM29085.1 - 1.7e-07 30.6 0.1 4.4e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ORF6C PF10552.4 GAM29085.1 - 0.088 12.5 0.2 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 ORF6C domain DUF1084 PF06454.6 GAM29086.1 - 9.4e-12 44.5 22.8 1.8e-11 43.5 15.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Glyco_transf_49 PF13896.1 GAM29087.1 - 2.7e-44 151.5 4.4 3e-38 131.7 2.6 2.5 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_transf_10 PF00852.14 GAM29087.1 - 1.4e-40 138.9 0.1 2.5e-40 138.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Glyco_tranf_2_2 PF10111.4 GAM29087.1 - 6.6e-06 25.4 1.9 1.5e-05 24.2 0.1 2.5 3 0 0 3 3 3 1 Glycosyltransferase like family 2 zf-RING_2 PF13639.1 GAM29089.1 - 2e-12 46.7 6.0 3.8e-12 45.8 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 GAM29089.1 - 2.5e-08 33.9 3.8 8.6e-08 32.1 2.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 GAM29089.1 - 1e-05 25.4 7.8 1.9e-05 24.6 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 GAM29089.1 - 8.3e-05 22.1 7.1 0.00021 20.8 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 GAM29089.1 - 0.00019 21.0 5.6 0.00036 20.2 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 GAM29089.1 - 0.00044 19.8 5.9 0.00073 19.1 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 GAM29089.1 - 0.025 14.2 6.1 0.082 12.6 4.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 GAM29089.1 - 0.033 14.0 2.2 0.072 12.9 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 GAM29089.1 - 0.057 12.9 3.6 0.11 11.9 2.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 GAM29089.1 - 2 8.5 6.2 6.6 6.8 4.3 1.9 1 0 0 1 1 1 0 RING-variant domain Utp14 PF04615.8 GAM29090.1 - 3e-124 415.8 81.7 3e-124 415.8 56.6 2.2 1 1 1 2 2 2 1 Utp14 protein LRR_4 PF12799.2 GAM29092.1 - 4.8e-18 64.3 19.5 9.7e-07 28.2 5.1 5.1 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM29092.1 - 1.2e-14 53.7 14.2 7.6e-09 35.2 0.3 3.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 GAM29092.1 - 2.7e-06 26.6 20.0 0.11 12.5 0.3 7.5 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_9 PF14580.1 GAM29092.1 - 0.00012 21.6 1.9 0.019 14.5 1.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat DNA_pol_lambd_f PF10391.4 GAM29092.1 - 0.092 12.3 0.1 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda LRR_7 PF13504.1 GAM29092.1 - 0.097 12.9 15.5 0.74 10.2 0.2 6.6 6 1 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 GAM29092.1 - 0.14 12.2 19.8 1.5 9.1 0.9 6.5 6 0 0 6 6 6 0 Leucine Rich repeat Beta_helix PF13229.1 GAM29093.1 - 5.4e-14 52.2 35.8 2.4e-10 40.4 4.1 3.8 1 1 2 3 3 3 2 Right handed beta helix region TALPID3 PF15324.1 GAM29093.1 - 7.9 3.6 8.2 11 3.2 5.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target OTU PF02338.14 GAM29094.1 - 2.2e-20 73.4 0.0 2.2e-20 73.4 0.0 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 GAM29094.1 - 1.6e-07 30.9 8.6 0.00035 19.9 0.0 3.5 1 1 2 3 3 3 2 Peptidase C65 Otubain Cob_adeno_trans PF01923.13 GAM29094.1 - 1.5 8.5 6.8 2.6 7.7 4.7 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase MRP-S31 PF15433.1 GAM29094.1 - 5.9 6.2 24.9 8.4 5.7 17.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 V_ATPase_I PF01496.14 GAM29094.1 - 8.1 4.1 15.7 6.5 4.4 10.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TFIIF_alpha PF05793.7 GAM29095.1 - 1.7e-21 76.2 60.1 1.7e-21 76.2 41.6 3.4 1 1 2 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Curto_V2 PF07325.6 GAM29095.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.5 3 1 1 4 4 4 0 Curtovirus V2 protein C2 PF00168.25 GAM29096.1 - 1.5e-18 66.4 0.0 3.1e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.12 GAM29096.1 - 5.4e-09 36.4 0.0 0.00063 20.1 0.0 4.0 3 1 0 3 3 3 2 Putative heavy-metal-binding DUF4156 PF13698.1 GAM29096.1 - 0.0035 17.1 0.1 0.05 13.4 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4156) Fiji_64_capsid PF05880.6 GAM29097.1 - 0.028 12.7 0.0 0.031 12.6 0.0 1.0 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein Pkinase PF00069.20 GAM29099.1 - 1.1e-28 100.1 0.0 9.4e-28 97.0 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain DSPc PF00782.15 GAM29099.1 - 7.3e-21 74.1 0.0 1.9e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.12 GAM29099.1 - 3.3e-13 49.3 0.0 5.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_Rpb2_6 PF00562.23 GAM29100.1 - 2.9e-122 408.1 6.7 6.6e-119 397.0 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 GAM29100.1 - 2.2e-65 219.3 0.6 3.7e-65 218.6 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 GAM29100.1 - 1.7e-49 167.7 0.0 5.3e-49 166.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 GAM29100.1 - 4.1e-32 110.2 0.0 1.5e-31 108.4 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 GAM29100.1 - 2.2e-23 81.8 1.6 4e-23 80.9 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 GAM29100.1 - 7.2e-22 76.9 0.1 2.5e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 GAM29100.1 - 1.7e-19 69.5 3.1 4.1e-19 68.2 2.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Hint PF01079.15 GAM29100.1 - 1.5e-07 30.8 0.6 3.8e-07 29.5 0.4 1.6 1 0 0 1 1 1 1 Hint module PT-HINT PF07591.6 GAM29100.1 - 1.6e-07 31.2 0.3 4.9e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 Pretoxin HINT domain Intein_splicing PF14890.1 GAM29100.1 - 3e-06 26.3 1.9 7.6e-06 25.0 1.3 1.7 1 1 0 1 1 1 1 Intein splicing domain Hom_end_hint PF05203.11 GAM29100.1 - 0.0013 18.4 0.7 0.0041 16.8 0.5 1.8 1 1 0 1 1 1 1 Hom_end-associated Hint efThoc1 PF11957.3 GAM29101.1 - 4.9e-66 223.2 23.3 6.3e-62 209.6 9.2 2.8 1 1 1 2 2 2 2 THO complex subunit 1 transcription elongation factor U79_P34 PF03064.11 GAM29101.1 - 0.0097 15.4 6.1 0.017 14.6 4.2 1.3 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF4484 PF14831.1 GAM29101.1 - 0.034 14.2 2.1 0.099 12.7 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Homeobox PF00046.24 GAM29102.1 - 2.1e-14 52.8 3.1 4e-14 51.9 2.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 GAM29102.1 - 0.00067 19.3 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.20 GAM29103.1 - 3e-77 259.2 0.0 4e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29103.1 - 2.9e-41 141.2 0.0 4e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM29103.1 - 0.00054 19.0 0.0 0.0011 18.0 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 GAM29103.1 - 0.0006 18.8 0.0 0.0015 17.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like DRP PF06044.7 GAM29103.1 - 0.022 13.7 0.3 0.038 12.9 0.2 1.3 1 0 0 1 1 1 0 Dam-replacing family YrbL-PhoP_reg PF10707.4 GAM29103.1 - 0.061 12.6 0.6 0.32 10.2 0.4 2.0 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL LRR_1 PF00560.28 GAM29104.1 - 0.028 14.4 5.5 18 5.8 0.3 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 GAM29104.1 - 0.046 13.7 8.7 1.1 9.4 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat hEGF PF12661.2 GAM29104.1 - 0.05 13.7 4.9 0.16 12.1 3.4 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF LRR_7 PF13504.1 GAM29104.1 - 0.059 13.5 0.6 27 5.5 0.1 4.4 3 0 0 3 3 3 0 Leucine rich repeat EGF_2 PF07974.8 GAM29104.1 - 0.09 12.9 11.3 0.2 11.8 7.9 1.6 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 GAM29105.1 - 2.3e-06 27.5 2.0 2.3e-06 27.5 1.4 6.2 5 2 2 7 7 7 3 IPT/TIG domain LRR_4 PF12799.2 GAM29105.1 - 0.00071 19.1 0.5 0.00071 19.1 0.3 6.9 4 1 3 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM29105.1 - 0.015 15.0 0.1 0.015 15.0 0.1 5.5 4 2 1 5 5 5 0 Leucine rich repeat EGF_2 PF07974.8 GAM29105.1 - 0.043 13.9 10.3 0.095 12.8 7.2 1.6 1 0 0 1 1 1 0 EGF-like domain MMS19_N PF14500.1 GAM29107.1 - 4.1e-88 295.0 21.9 3.8e-85 285.3 0.1 4.5 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 GAM29107.1 - 3.1e-56 190.8 28.7 1.2e-48 165.8 10.1 4.3 3 2 1 5 5 5 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 GAM29107.1 - 7.4e-11 42.2 2.5 0.16 12.5 0.0 6.3 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.1 GAM29107.1 - 6.4e-09 35.9 0.2 3.6e-05 23.9 0.0 4.3 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 GAM29107.1 - 7.9e-08 31.7 5.2 0.18 11.9 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.2 GAM29107.1 - 0.00033 20.9 4.8 0.031 14.6 0.2 4.3 4 2 0 4 4 4 1 Vacuolar 14 Fab1-binding region Pro-NT_NN PF07421.6 GAM29107.1 - 0.0048 16.4 0.5 0.011 15.1 0.4 1.6 1 0 0 1 1 1 1 Neurotensin/neuromedin N precursor IFRD PF05004.8 GAM29107.1 - 0.033 13.2 10.8 0.27 10.2 0.1 3.6 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Arm PF00514.18 GAM29107.1 - 0.64 9.9 7.2 15 5.5 0.6 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cpn60_TCP1 PF00118.19 GAM29108.1 - 8.7e-18 64.1 2.6 2.7e-17 62.5 0.4 2.2 2 1 0 2 2 2 1 TCP-1/cpn60 chaperonin family Peptidase_S10 PF00450.17 GAM29108.1 - 0.0014 17.8 0.3 0.53 9.3 0.0 2.3 2 0 0 2 2 2 2 Serine carboxypeptidase IF-2B PF01008.12 GAM29108.1 - 0.13 11.2 1.2 9.3 5.1 0.0 2.2 2 0 0 2 2 2 0 Initiation factor 2 subunit family Glyco_transf_49 PF13896.1 GAM29109.1 - 3.1e-47 161.2 1.7 7.4e-40 136.9 1.4 2.5 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 GAM29109.1 - 2.1e-07 30.3 0.1 2.1e-07 30.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyltransferase like family 2 MoeA_N PF03453.12 GAM29109.1 - 0.26 10.6 0.0 0.44 9.8 0.0 1.3 1 0 0 1 1 1 0 MoeA N-terminal region (domain I and II) RR_TM4-6 PF06459.7 GAM29109.1 - 1.6 8.5 5.1 2.8 7.7 3.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_10 PF00852.14 GAM29110.1 - 1.2e-47 162.2 2.3 1.5e-47 161.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) YARHG PF13308.1 GAM29110.1 - 0.014 14.9 0.2 0.039 13.4 0.1 1.8 1 0 0 1 1 1 0 YARHG domain Glyco_hydro_18 PF00704.23 GAM29111.1 - 9.8e-29 100.8 0.2 1.4e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nodulin_late PF07127.6 GAM29111.1 - 0.029 14.4 0.6 0.71 10.0 0.1 2.4 2 0 0 2 2 2 0 Late nodulin protein Glyco_transf_10 PF00852.14 GAM29112.1 - 1e-46 159.1 1.3 1.4e-46 158.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) G10 PF01125.12 GAM29114.1 - 3e-61 205.2 7.6 3.3e-61 205.0 5.3 1.0 1 0 0 1 1 1 1 G10 protein DUF1084 PF06454.6 GAM29115.1 - 3e-10 39.6 22.1 5.3e-10 38.8 15.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) ASFV_J13L PF05568.6 GAM29115.1 - 0.29 10.6 4.4 0.78 9.2 3.1 1.7 1 0 0 1 1 1 0 African swine fever virus J13L protein Sec23_trunk PF04811.10 GAM29116.1 - 6.1e-66 222.2 0.4 1.4e-65 221.0 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 GAM29116.1 - 3e-24 84.4 2.3 3.7e-24 84.1 0.7 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 GAM29116.1 - 1.7e-18 65.8 2.3 3.4e-18 64.9 1.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 GAM29116.1 - 9e-18 64.5 0.2 2.1e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 GAM29116.1 - 5.8e-05 22.7 0.0 5.8e-05 22.7 0.0 3.1 4 0 0 4 4 4 1 Gelsolin repeat Pkinase_Tyr PF07714.12 GAM29117.1 - 1.6e-53 181.4 0.0 2.8e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM29117.1 - 4e-51 173.6 0.0 6.6e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 GAM29117.1 - 5.8e-23 81.0 0.8 1.5e-11 44.4 0.0 4.3 2 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 GAM29117.1 - 3.9e-19 67.4 1.0 8.8e-07 28.4 0.1 6.2 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 GAM29117.1 - 3.7e-14 52.7 6.3 9.7e-10 38.7 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29117.1 - 8.4e-11 41.0 2.2 0.071 13.3 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 GAM29117.1 - 1.3e-10 41.1 1.7 0.011 15.9 0.0 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Kinase-like PF14531.1 GAM29117.1 - 7.3e-05 21.8 0.0 0.00015 20.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 GAM29117.1 - 0.011 15.4 3.0 0.022 14.5 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF3100 PF11299.3 GAM29118.1 - 0.16 11.1 0.7 0.22 10.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) NDT80_PhoG PF05224.7 GAM29119.1 - 1.4e-28 100.1 0.1 1.4e-28 100.1 0.1 3.6 2 2 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 GAM29119.1 - 3.7e-08 33.3 0.0 7.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.1 GAM29119.1 - 0.001 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 CCDC-167 PF15188.1 GAM29119.1 - 0.049 13.5 0.8 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1212 PF06738.7 GAM29119.1 - 0.076 12.4 0.0 0.076 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Methyltransf_18 PF12847.2 GAM29120.1 - 3.2e-18 66.3 0.0 4.6e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 GAM29120.1 - 9.9e-17 60.9 0.0 1.3e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 GAM29120.1 - 2.4e-10 40.7 0.0 3.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 GAM29120.1 - 5.4e-10 39.6 0.1 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 GAM29120.1 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 GAM29120.1 - 2.7e-09 36.9 0.0 4.9e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 GAM29120.1 - 6.3e-09 36.1 0.0 9.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 GAM29120.1 - 2.4e-07 30.0 0.0 3.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 GAM29120.1 - 6.3e-07 28.9 0.0 8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 GAM29120.1 - 1.6e-05 24.1 0.1 2.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 GAM29120.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF1363 PF07101.6 GAM29120.1 - 0.012 15.6 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) Methyltransf_32 PF13679.1 GAM29120.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 GAM29120.1 - 0.072 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 GAM29120.1 - 0.094 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AviRa PF11599.3 GAM29120.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa SIR2 PF02146.12 GAM29121.1 - 9.1e-25 87.3 0.0 1.6e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family HTH_8 PF02954.14 GAM29121.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family tRNA-synt_2b PF00587.20 GAM29123.1 - 3.6e-46 156.8 0.9 6.9e-46 155.9 0.6 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 GAM29123.1 - 2.2e-20 72.4 0.8 4.3e-20 71.4 0.6 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 GAM29123.1 - 3.3e-12 46.0 0.0 6.7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 GAM29123.1 - 2.8e-11 43.0 0.0 1.4e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 TGS domain DUF1246 PF06849.7 GAM29123.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) UvsW PF11637.3 GAM29123.1 - 0.097 12.3 0.6 0.69 9.6 0.0 2.6 3 0 0 3 3 3 0 ATP-dependant DNA helicase UvsW LRR_4 PF12799.2 GAM29124.1 - 8.9e-25 85.8 23.6 4.8e-08 32.4 0.4 6.4 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM29124.1 - 1.2e-22 79.4 22.5 4.7e-10 39.0 1.5 4.9 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 GAM29124.1 - 2.1e-13 48.2 23.9 0.29 11.3 1.0 10.1 9 1 1 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.1 GAM29124.1 - 1.5e-08 33.8 22.5 9 6.7 0.0 10.0 8 2 2 10 10 10 4 Leucine Rich repeat LRR_7 PF13504.1 GAM29124.1 - 5e-07 28.8 18.3 9.3 6.9 0.1 9.9 10 0 0 10 10 10 1 Leucine rich repeat LRR_9 PF14580.1 GAM29124.1 - 3.5e-06 26.6 1.0 0.0041 16.6 0.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.1 GAM29124.1 - 0.00077 19.1 0.1 0.0024 17.5 0.1 1.7 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) Epimerase PF01370.16 GAM29125.1 - 4.3e-62 209.6 0.3 5.9e-62 209.1 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM29125.1 - 3.6e-26 91.4 0.0 5.1e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 GAM29125.1 - 6.1e-23 81.1 0.0 3.8e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 GAM29125.1 - 5.6e-22 77.9 0.0 7.3e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 GAM29125.1 - 3.8e-21 75.1 1.0 4.4e-19 68.4 0.7 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 GAM29125.1 - 2.6e-09 37.3 0.0 3.3e-08 33.7 0.0 2.3 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 GAM29125.1 - 3e-06 27.2 0.2 7.7e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 GAM29125.1 - 0.022 14.4 0.3 0.092 12.4 0.2 2.0 1 1 0 1 1 1 0 KR domain GST_C_4 PF14834.1 GAM29125.1 - 0.041 13.8 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DAO PF01266.19 GAM29125.1 - 0.15 10.9 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ank_4 PF13637.1 GAM29126.1 - 1.5e-21 76.2 3.0 4e-11 43.1 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM29126.1 - 8.5e-19 66.3 1.3 2.8e-11 42.6 0.3 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 GAM29126.1 - 4.6e-18 65.3 0.3 7.2e-18 64.7 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM29126.1 - 1.2e-15 57.1 1.7 1e-08 35.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29126.1 - 4.6e-13 48.0 0.7 4.2e-07 29.5 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat DUF3094 PF11293.3 GAM29127.1 - 0.0019 17.5 0.4 0.0092 15.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3094) DUF2448 PF10476.4 GAM29127.1 - 1.7 8.1 6.3 2 7.9 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) TGS PF02824.16 GAM29128.1 - 3.4e-22 78.0 0.0 5.8e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 GAM29128.1 - 3.4e-18 65.6 0.0 5.1e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 GAM29128.1 - 7.5e-09 35.0 0.0 1.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 GAM29128.1 - 0.00027 21.4 0.0 0.00068 20.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 GAM29128.1 - 0.00085 19.1 0.2 0.13 12.1 0.0 2.3 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 GAM29128.1 - 0.039 13.1 0.1 0.11 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 GAM29128.1 - 0.049 12.8 0.1 0.12 11.5 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 GAM29128.1 - 0.051 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 GAM29128.1 - 0.054 12.2 0.7 0.23 10.1 0.1 2.1 1 1 1 2 2 2 0 ArgK protein AIG1 PF04548.11 GAM29128.1 - 0.076 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_17 PF13207.1 GAM29128.1 - 0.14 12.9 1.3 0.97 10.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain Y_phosphatase2 PF03162.8 GAM29129.1 - 1e-06 28.2 0.0 1.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 GAM29129.1 - 3e-06 26.8 0.0 4.3e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.15 GAM29129.1 - 4e-06 26.4 0.0 9.5e-06 25.2 0.0 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 GAM29129.1 - 6.6e-05 23.2 0.2 0.00019 21.7 0.0 1.6 2 1 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 GAM29129.1 - 0.00014 21.8 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 GAM29129.1 - 0.00093 18.6 0.0 0.0017 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DUF1940 PF09155.5 GAM29129.1 - 0.055 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) RRM_1 PF00076.17 GAM29132.1 - 2.3e-27 94.4 7.0 9.7e-12 44.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM29132.1 - 1.1e-18 67.0 1.5 1.1e-06 28.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 GAM29132.1 - 6.3e-12 45.1 6.6 0.00012 21.8 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAGA-Tad1 PF12767.2 GAM29133.1 - 1.2e-07 31.7 8.1 1.2e-07 31.7 5.6 2.3 2 2 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit SAGA-Tad1 PF12767.2 GAM29134.1 - 3.2e-12 46.6 0.1 3.2e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF1777 PF08648.7 GAM29134.1 - 0.022 14.5 7.5 0.025 14.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CENP-B_dimeris PF09026.5 GAM29134.1 - 0.03 14.5 0.6 0.039 14.1 0.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Atrophin-1 PF03154.10 GAM29134.1 - 0.056 11.5 0.2 0.054 11.6 0.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family SRRM_C PF15230.1 GAM29134.1 - 0.11 12.6 5.0 0.17 11.9 3.5 1.3 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus U79_P34 PF03064.11 GAM29134.1 - 0.38 10.2 5.2 0.32 10.4 3.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2956 PF11169.3 GAM29134.1 - 1.2 9.1 3.5 1.7 8.6 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DEAD PF00270.24 GAM29135.1 - 2.7e-41 140.8 4.7 4e-41 140.3 1.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 GAM29135.1 - 6.3e-30 102.8 0.2 1.3e-29 101.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 GAM29135.1 - 3.6e-06 25.6 0.1 0.015 13.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_30 PF13604.1 GAM29135.1 - 0.00012 21.7 0.3 0.00066 19.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM29135.1 - 0.00027 20.6 0.1 0.00093 18.9 0.0 1.9 1 1 1 2 2 2 1 Part of AAA domain tRNA-synt_1b PF00579.20 GAM29135.1 - 0.00084 18.5 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ResIII PF04851.10 GAM29135.1 - 0.0017 18.2 0.1 0.022 14.6 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 GAM29135.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 GAM29135.1 - 0.028 13.4 0.6 0.1 11.6 0.0 2.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_11 PF13086.1 GAM29135.1 - 0.13 11.8 2.0 0.37 10.3 1.4 2.0 1 1 0 1 1 1 0 AAA domain FNIP PF05725.7 GAM29136.1 - 1.9e-15 56.4 9.8 8.3e-09 35.2 0.0 4.2 4 0 0 4 4 4 3 FNIP Repeat 2OG-FeII_Oxy_3 PF13640.1 GAM29137.1 - 1.6e-05 25.3 0.0 4.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 GAM29137.1 - 0.00013 22.2 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Terpene_synth_C PF03936.11 GAM29139.1 - 0.00016 20.9 1.8 0.00029 20.1 1.3 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 GAM29140.1 - 6.7e-12 44.6 0.3 3.9e-07 28.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Nop53 PF07767.6 GAM29141.1 - 0.00038 19.5 2.1 0.00047 19.2 1.4 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Exonuc_VII_L PF02601.10 GAM29141.1 - 0.58 9.2 4.5 0.81 8.8 3.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lge1 PF11488.3 GAM29141.1 - 0.72 10.0 10.5 0.19 11.9 0.8 2.8 2 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF342 PF03961.8 GAM29141.1 - 0.79 8.0 4.5 1 7.7 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 GAM29141.1 - 9.5 5.1 10.5 13 4.7 7.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Fb_signal PF08341.6 GAM29143.1 - 0.013 15.5 0.0 4.3 7.4 0.0 2.6 3 0 0 3 3 3 0 Fibronectin-binding protein signal sequence p450 PF00067.17 GAM29144.1 - 2.4e-102 342.8 0.0 2.8e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec7 PF01369.15 GAM29145.1 - 7.7e-56 188.7 1.8 7.7e-56 188.7 1.2 2.6 2 1 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 GAM29145.1 - 1e-35 122.6 3.6 1e-35 122.6 2.5 4.8 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 GAM29145.1 - 7e-19 67.1 0.3 7e-19 67.1 0.2 5.8 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) SH3_9 PF14604.1 GAM29146.1 - 3.1e-19 68.3 0.3 1.6e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 GAM29146.1 - 6.4e-18 63.9 0.4 2.2e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 GAM29146.1 - 1e-13 50.4 0.4 2e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 SH3 domain PCI_Csn8 PF10075.4 GAM29147.1 - 6.1e-26 90.9 0.9 1.1e-25 90.0 0.0 1.9 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 GAM29147.1 - 7.1e-25 87.7 3.3 9e-25 87.4 2.0 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF4455 PF14643.1 GAM29147.1 - 0.032 12.8 1.7 0.055 12.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF1703 PF08011.6 GAM29147.1 - 0.06 13.0 1.7 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1703) PCI PF01399.22 GAM29148.1 - 6e-15 55.4 1.0 1.2e-14 54.5 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.1 GAM29148.1 - 0.0041 17.0 0.4 0.038 13.9 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 GAM29148.1 - 0.025 14.1 0.4 0.9 9.2 0.1 2.5 1 1 1 2 2 2 0 TPR repeat TPR_7 PF13176.1 GAM29148.1 - 0.035 13.9 0.9 0.47 10.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 GAM29148.1 - 0.064 13.5 2.6 0.21 11.9 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2804 PF10974.3 GAM29149.1 - 8.6e-96 320.6 1.3 9.8e-96 320.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) MIF4G PF02854.14 GAM29151.1 - 8.6e-32 110.2 10.4 7.1e-31 107.2 4.4 2.5 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 GAM29151.1 - 2.4e-08 33.6 1.4 0.00012 21.7 0.1 2.8 2 0 0 2 2 2 2 MA3 domain Uso1_p115_head PF04869.9 GAM29152.1 - 1.2e-36 126.0 0.4 1.2e-36 126.0 0.3 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region PolyA_pol PF01743.15 GAM29152.1 - 0.0059 16.8 1.5 0.0059 16.8 1.0 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain NIF PF03031.13 GAM29155.1 - 3.2e-55 186.1 0.5 5e-55 185.5 0.4 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 GAM29155.1 - 0.05 13.8 0.3 0.49 10.6 0.0 2.1 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Xpo1 PF08389.7 GAM29156.1 - 3.5e-18 65.9 17.1 5e-18 65.4 0.2 6.4 6 1 1 7 7 7 1 Exportin 1-like protein DUF1722 PF08349.6 GAM29156.1 - 0.0086 15.9 1.4 0.061 13.2 0.0 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) IBN_N PF03810.14 GAM29156.1 - 0.05 13.5 0.8 0.39 10.6 0.0 3.0 3 0 0 3 3 3 0 Importin-beta N-terminal domain TPR_11 PF13414.1 GAM29157.1 - 2e-10 40.1 1.1 2.7e-05 23.7 0.1 2.9 1 1 2 3 3 3 2 TPR repeat DUF1736 PF08409.6 GAM29157.1 - 1.2e-09 37.6 2.5 1.2e-09 37.6 1.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_1 PF00515.23 GAM29157.1 - 6e-07 28.8 0.4 7.9e-06 25.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 GAM29157.1 - 6.3e-06 25.7 0.1 0.00013 21.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 GAM29157.1 - 4.6e-05 23.2 2.4 2 8.8 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM29157.1 - 0.0002 21.2 0.8 0.065 13.1 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM29157.1 - 0.0033 17.0 1.6 0.32 10.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM29157.1 - 0.0039 17.5 0.0 1.7 9.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat 60KD_IMP PF02096.15 GAM29157.1 - 0.011 15.4 0.0 0.23 11.0 0.0 2.4 1 1 1 2 2 2 0 60Kd inner membrane protein TPR_16 PF13432.1 GAM29157.1 - 0.014 16.0 0.2 0.086 13.5 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 GAM29157.1 - 0.015 14.4 0.3 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP DUF4131 PF13567.1 GAM29157.1 - 0.44 9.9 3.1 1.2 8.5 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ctr PF04145.10 GAM29158.1 - 0.049 13.6 0.5 1.6 8.7 0.0 2.4 1 1 1 2 2 2 0 Ctr copper transporter family DUF3687 PF12459.3 GAM29158.1 - 0.095 11.9 0.5 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein DUF4436 PF14494.1 GAM29158.1 - 0.33 10.1 2.3 1.2 8.3 0.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4436) Actin PF00022.14 GAM29159.1 - 1.8e-52 178.0 0.0 2e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 GAM29160.1 - 3.4e-87 292.4 0.0 3.9e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 GAM29160.1 - 0.034 14.5 0.0 0.091 13.1 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RPAP2_Rtr1 PF04181.8 GAM29161.1 - 0.29 11.2 3.4 0.62 10.1 2.3 1.8 1 1 0 1 1 1 0 Rtr1/RPAP2 family IlvC PF01450.14 GAM29161.1 - 1.9 8.4 4.5 0.8 9.6 0.3 2.2 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain V_ATPase_I PF01496.14 GAM29161.1 - 4.1 5.1 7.8 4.5 4.9 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_S19e PF01090.14 GAM29162.1 - 5.4e-52 174.9 0.0 6.1e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L21e PF01157.13 GAM29163.1 - 1.3e-36 124.3 5.1 2e-36 123.7 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e IBN_N PF03810.14 GAM29164.1 - 2.2e-06 27.5 1.1 2.2e-06 27.5 0.7 3.7 4 1 1 5 5 5 1 Importin-beta N-terminal domain Kelch_1 PF01344.20 GAM29165.1 - 3.5e-42 141.7 19.7 3e-11 42.6 0.2 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 GAM29165.1 - 7.5e-37 124.6 23.4 8.4e-09 35.3 0.1 7.6 8 0 0 8 8 8 7 Galactose oxidase, central domain Kelch_4 PF13418.1 GAM29165.1 - 3.9e-36 122.5 15.0 1.6e-06 27.7 1.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 GAM29165.1 - 2.1e-35 120.1 24.5 1.7e-08 34.2 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 GAM29165.1 - 1.7e-34 116.5 24.3 3.6e-07 30.0 0.4 6.5 3 1 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 GAM29165.1 - 3e-29 99.6 16.8 4.4e-07 29.3 0.0 6.5 6 0 0 6 6 6 6 Kelch motif F-box-like PF12937.2 GAM29165.1 - 2.9e-07 30.0 1.0 2.9e-07 30.0 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 GAM29165.1 - 7.6e-07 28.6 0.4 1.9e-06 27.3 0.3 1.7 1 0 0 1 1 1 1 F-box domain CDI PF02234.14 GAM29166.1 - 0.14 11.9 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor PRKCSH_1 PF13015.1 GAM29167.1 - 0.0011 18.4 1.2 0.0014 18.1 0.9 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 GAM29167.1 - 0.36 10.0 4.1 0.53 9.4 2.8 1.4 1 1 0 1 1 1 0 Autophagy-related protein 27 RasGEF PF00617.14 GAM29168.1 - 1.6e-30 106.2 1.8 2.8e-30 105.4 0.3 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 GAM29168.1 - 1.2e-15 57.4 2.1 6.4e-15 55.1 1.5 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGAP PF00620.22 GAM29168.1 - 3e-14 52.8 0.0 9.3e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain Pribosyltran_N PF13793.1 GAM29169.1 - 4.8e-46 155.2 0.8 1e-43 147.7 0.0 2.9 3 1 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 GAM29169.1 - 2.5e-29 102.3 3.7 1e-28 100.3 1.0 2.4 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 GAM29169.1 - 0.0017 18.0 2.0 0.0053 16.4 1.4 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Dus PF01207.12 GAM29170.1 - 4.7e-47 160.3 1.7 2.9e-46 157.7 0.4 2.0 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) Rifin_STEVOR PF02009.11 GAM29170.1 - 0.03 13.9 3.5 0.048 13.2 1.5 1.8 2 0 0 2 2 2 0 Rifin/stevor family Dicty_REP PF05086.7 GAM29170.1 - 0.28 8.9 13.4 0.38 8.4 9.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 GAM29170.1 - 4 7.1 33.1 0.3 10.8 19.1 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein FXa_inhibition PF14670.1 GAM29171.1 - 4.6e-07 29.8 10.7 4.6e-07 29.8 7.4 4.8 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site TIG PF01833.19 GAM29171.1 - 1.6e-06 27.9 2.1 8.9e-06 25.6 1.4 2.4 1 0 0 1 1 1 1 IPT/TIG domain FXa_inhibition PF14670.1 GAM29172.1 - 1.3e-14 54.0 27.9 3.6e-09 36.5 6.5 3.5 3 0 0 3 3 3 2 Coagulation Factor Xa inhibitory site TIG PF01833.19 GAM29172.1 - 4.9e-06 26.4 3.9 5.7e-06 26.2 1.0 2.4 2 0 0 2 2 2 1 IPT/TIG domain cEGF PF12662.2 GAM29172.1 - 0.0011 18.5 1.2 0.0011 18.5 0.8 3.6 3 1 0 3 3 3 2 Complement Clr-like EGF-like Coiled PF05710.7 GAM29173.1 - 0.27 11.7 8.8 0.35 11.3 6.1 1.4 1 1 0 1 1 1 0 Coiled coil UQ_con PF00179.21 GAM29174.1 - 6.5e-47 158.4 0.2 7.3e-47 158.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 GAM29174.1 - 3.8e-06 26.6 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 GAM29174.1 - 0.0059 16.4 0.4 0.0078 16.0 0.3 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 GAM29174.1 - 0.033 13.8 0.1 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 UEV domain Xpo1 PF08389.7 GAM29175.1 - 3.1e-11 43.3 0.3 3.1e-11 43.3 0.2 5.8 6 1 0 6 6 6 1 Exportin 1-like protein SR-25 PF10500.4 GAM29175.1 - 9e-05 22.0 1.3 9e-05 22.0 0.9 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med3 PF11593.3 GAM29175.1 - 0.0051 16.0 7.1 0.0051 16.0 4.9 2.9 2 1 0 2 2 2 1 Mediator complex subunit 3 fungal Suf PF05843.9 GAM29175.1 - 0.64 9.7 7.5 1.7 8.3 0.6 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DnaJ-X PF14308.1 GAM29175.1 - 0.66 9.1 5.6 1.7 7.9 0.3 2.4 2 0 0 2 2 2 0 X-domain of DnaJ-containing Pex14_N PF04695.8 GAM29175.1 - 1.4 8.9 19.2 1.6 8.7 1.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cellulase PF00150.13 GAM29176.1 - 4.5e-23 81.8 0.1 8.4e-18 64.5 0.0 2.5 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 GAM29176.1 - 0.012 14.9 0.9 0.015 14.6 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 PHF5 PF03660.9 GAM29177.1 - 4.5e-46 155.3 10.9 5.1e-46 155.1 7.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 GAM29177.1 - 1.2 6.7 8.5 1.3 6.6 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 GAM29177.1 - 1.5 8.7 16.7 1.1 9.1 1.8 3.0 1 1 1 2 2 2 0 Double zinc ribbon PHD PF00628.24 GAM29177.1 - 7.3 6.3 17.8 1.2e+02 2.4 12.3 2.8 1 1 0 1 1 1 0 PHD-finger RhoGEF PF00621.15 GAM29179.1 - 1.7e-35 122.5 0.1 3.3e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 GAM29179.1 - 5e-06 26.6 0.9 2.9e-05 24.1 0.0 2.7 3 0 0 3 3 3 1 PH domain PC4 PF02229.11 GAM29180.1 - 0.066 12.4 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Rogdi_lz PF10259.4 GAM29181.1 - 8.9e-15 54.5 12.5 1.3e-09 37.5 6.9 3.2 2 1 0 2 2 2 2 Rogdi leucine zipper containing protein DUF572 PF04502.8 GAM29182.1 - 7.9e-84 281.6 19.6 3.4e-83 279.5 13.6 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) RNA_pol_N PF01194.12 GAM29182.1 - 0.084 12.9 3.0 0.15 12.1 0.0 2.7 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-PHD-like PF15446.1 GAM29182.1 - 0.087 12.1 2.5 0.19 11.0 1.7 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Yippee-Mis18 PF03226.9 GAM29182.1 - 0.11 12.5 2.5 12 6.0 0.0 3.1 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2610 PF11020.3 GAM29182.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) TF_Zn_Ribbon PF08271.7 GAM29182.1 - 0.38 10.1 3.1 0.36 10.1 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-MIZ PF02891.15 GAM29183.1 - 1.1e-16 60.0 8.4 2.4e-16 58.9 5.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 GAM29183.1 - 0.00066 19.1 2.6 0.0014 18.0 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 GAM29183.1 - 0.11 11.9 0.2 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 SAP domain zf-Sec23_Sec24 PF04810.10 GAM29183.1 - 0.55 9.8 6.3 1.1 8.8 4.3 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ATG27 PF09451.5 GAM29184.1 - 2.1e-23 82.9 4.6 8.8e-23 80.8 3.2 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 GAM29184.1 - 1.8e-06 27.1 4.2 5.6e-05 22.2 0.1 2.3 2 1 0 2 2 2 2 Mannose-6-phosphate receptor PRKCSH_1 PF13015.1 GAM29184.1 - 3e-05 23.5 0.2 4.4e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 GAM29185.1 - 7.3e-24 84.4 4.0 3.6e-22 78.8 2.7 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 GAM29185.1 - 1.4e-06 28.1 0.9 6.9e-05 22.6 0.5 2.1 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 GAM29185.1 - 8.4e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.10 GAM29185.1 - 0.0078 15.2 1.9 0.021 13.8 0.3 2.2 2 1 0 2 2 2 1 Mannose-6-phosphate receptor zf-TFIIB PF13453.1 GAM29185.1 - 0.095 11.9 0.1 0.21 10.8 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger IBN_N PF03810.14 GAM29186.1 - 0.00039 20.2 0.0 0.00039 20.2 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF1539 PF07560.6 GAM29186.1 - 0.014 15.2 4.4 0.36 10.7 0.0 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1539) VDE PF07137.6 GAM29186.1 - 0.055 13.3 0.1 4.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Violaxanthin de-epoxidase (VDE) Ribosomal_L18e PF00828.14 GAM29187.1 - 6.7e-33 113.7 0.1 8.1e-33 113.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Glyco_hydro_38 PF01074.17 GAM29188.1 - 2.3e-89 299.2 3.1 3.6e-89 298.6 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 GAM29188.1 - 1e-66 225.6 4.5 1.3e-66 225.3 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 GAM29188.1 - 4.8e-20 71.5 0.2 1.1e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Agenet PF05641.7 GAM29189.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Agenet domain Dicty_REP PF05086.7 GAM29189.1 - 3.2 5.3 8.8 5.3 4.6 6.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Clat_adaptor_s PF01217.15 GAM29190.1 - 1.1e-07 31.6 2.9 1.4e-07 31.3 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AMP-binding PF00501.23 GAM29191.1 - 6.6e-55 186.1 0.0 9.8e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 GAM29191.1 - 1.4e-52 178.1 0.0 2.1e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 GAM29191.1 - 1.8e-08 34.5 0.0 5.7e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 GAM29191.1 - 2.6e-06 27.0 0.0 1.1e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 GAM29191.1 - 1e-05 24.3 0.3 0.00027 19.7 0.2 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ZZ PF00569.12 GAM29191.1 - 0.025 14.1 10.6 0.058 12.9 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type NAD_binding_10 PF13460.1 GAM29191.1 - 0.033 14.2 0.0 4.4 7.2 0.0 3.0 4 0 0 4 4 4 0 NADH(P)-binding adh_short PF00106.20 GAM29192.1 - 7.6e-25 87.7 0.0 1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 GAM29192.1 - 2.7e-17 63.3 0.0 3.5e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 GAM29192.1 - 1.2e-07 31.2 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 GAM29192.1 - 1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 GAM29192.1 - 9.2e-05 21.9 0.1 0.0012 18.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 GAM29192.1 - 0.00019 21.5 0.0 0.00032 20.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding eRF1_1 PF03463.10 GAM29193.1 - 7.8e-43 145.2 1.5 1.4e-42 144.3 1.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 GAM29193.1 - 3.7e-25 88.7 0.0 6.2e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 GAM29193.1 - 3e-23 82.2 0.0 7.4e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 CobT PF06213.7 GAM29193.1 - 0.4 9.7 11.6 0.7 8.9 8.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 GAM29193.1 - 0.5 8.3 12.4 0.78 7.7 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 GAM29193.1 - 2.3 6.6 15.3 3.2 6.1 10.6 1.2 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 GAM29193.1 - 7.7 6.3 20.7 20 5.0 14.3 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1604 PF07713.8 GAM29194.1 - 4.8e-37 125.6 2.6 4.8e-37 125.6 1.8 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 GAM29194.1 - 6.3e-05 22.6 0.2 0.00017 21.2 0.2 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 GAM29194.1 - 0.011 15.5 0.0 0.011 15.5 0.0 4.1 4 0 0 4 4 4 0 DExH-box splicing factor binding site Na_K-ATPase PF00287.13 GAM29194.1 - 7.6 5.2 8.7 9.9 4.8 3.7 2.2 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain DUF2742 PF10888.3 GAM29195.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) ArfGap PF01412.13 GAM29196.1 - 3.5e-41 139.6 0.0 7.6e-41 138.5 0.0 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 GAM29196.1 - 5.7e-10 39.3 0.3 1.1e-09 38.3 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM29196.1 - 0.02 15.1 0.2 0.093 12.9 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PAP2_C PF14360.1 GAM29196.1 - 0.053 13.7 0.1 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Glyco_hydro_9 PF00759.14 GAM29197.1 - 4.5e-140 467.4 7.6 5.1e-140 467.2 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 MFS_1 PF07690.11 GAM29198.1 - 5.1e-47 160.2 29.3 5.1e-47 160.2 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 GAM29198.1 - 0.00094 18.0 0.6 0.00094 18.0 0.4 2.2 2 0 0 2 2 2 1 BT1 family DUF1228 PF06779.9 GAM29198.1 - 0.59 10.2 10.4 0.64 10.0 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Pkinase PF00069.20 GAM29199.1 - 1.4e-78 263.6 0.0 1.7e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29199.1 - 3.7e-38 131.0 0.0 4.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM29199.1 - 1.5e-07 30.7 0.1 3e-05 23.1 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 GAM29199.1 - 3.2e-05 23.0 0.0 4.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM29199.1 - 0.0024 17.6 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM29199.1 - 0.0099 15.2 0.2 0.023 14.0 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 GAM29199.1 - 0.033 12.9 0.1 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Acyltransferase PF01553.16 GAM29200.1 - 4.8e-23 81.0 0.0 7.2e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Pkinase_Tyr PF07714.12 GAM29201.1 - 2.7e-53 180.6 0.0 3.6e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM29201.1 - 6.8e-49 166.3 0.0 4.8e-48 163.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Daxx PF03344.10 GAM29201.1 - 0.0013 17.3 21.6 0.0013 17.3 15.0 1.6 2 0 0 2 2 2 1 Daxx Family Kinase-like PF14531.1 GAM29201.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 GAM29201.1 - 0.23 10.4 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 GAM29201.1 - 8.3 4.1 22.5 13 3.5 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 GAM29202.1 - 1.5e-08 34.1 0.1 0.00043 20.0 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Cystatin PF00031.16 GAM29203.1 - 0.0001 22.3 0.7 0.0003 20.8 0.5 1.7 1 1 0 1 1 1 1 Cystatin domain Acetyltransf_1 PF00583.19 GAM29205.1 - 1.6e-16 60.1 0.1 2.2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 GAM29205.1 - 5.3e-08 32.5 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 GAM29205.1 - 4.2e-07 30.0 0.0 6.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM29205.1 - 1.2e-06 28.5 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 GAM29205.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 GAM29205.1 - 0.003 17.4 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 GAM29205.1 - 0.0033 17.3 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SPOR PF05036.8 GAM29205.1 - 0.15 12.2 0.0 0.25 11.4 0.0 1.5 1 1 0 1 1 1 0 Sporulation related domain PKD_channel PF08016.7 GAM29206.1 - 3.3e-42 144.4 18.5 3.3e-42 144.4 12.8 2.0 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 GAM29206.1 - 0.00015 21.1 28.4 0.00015 21.1 19.7 2.5 2 1 1 3 3 3 1 Ion transport protein FUSC PF04632.7 GAM29206.1 - 2 6.7 9.2 3 6.1 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family E1-E2_ATPase PF00122.15 GAM29207.1 - 2.7e-27 95.2 0.9 1.7e-26 92.7 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 GAM29207.1 - 5.8e-15 55.9 0.0 1.4e-14 54.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 GAM29207.1 - 6.2e-12 45.3 0.1 3.2e-11 43.0 0.0 2.3 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 GAM29207.1 - 2.2e-10 41.3 0.5 5.6e-09 36.7 0.3 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 GAM29207.1 - 0.0024 17.5 2.1 0.0068 16.0 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 GAM29209.1 - 6.1e-27 93.7 9.9 1.5e-07 31.6 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 GAM29209.1 - 1.5e-18 66.3 7.5 0.043 14.0 0.1 8.3 6 1 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29209.1 - 5.1e-18 63.3 12.6 0.24 11.7 0.1 10.3 8 2 2 10 10 10 4 Ankyrin repeat Ank_4 PF13637.1 GAM29209.1 - 1.5e-16 60.3 20.2 0.00078 19.8 1.3 8.7 5 5 3 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 GAM29209.1 - 1.4e-15 56.2 11.8 0.035 13.9 0.2 8.7 9 0 0 9 9 9 6 Ankyrin repeat DUF3447 PF11929.3 GAM29209.1 - 0.0058 16.4 8.4 0.25 11.1 0.0 4.0 4 1 1 5 5 5 2 Domain of unknown function (DUF3447) CCDC71L PF15374.1 GAM29209.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Acetyltransf_13 PF13880.1 GAM29211.1 - 2.8e-22 78.2 0.0 6.5e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 GAM29211.1 - 1.9e-11 43.2 0.5 3.9e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 GAM29211.1 - 0.0039 17.1 0.0 0.0084 16.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM29211.1 - 0.0042 17.2 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 GAM29211.1 - 0.04 13.8 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 Ribosomal_L5_C PF00673.16 GAM29212.1 - 2.3e-22 78.5 0.1 3.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 GAM29212.1 - 4.4e-18 64.8 0.3 2.7e-17 62.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 DUF1643 PF07799.7 GAM29212.1 - 0.06 13.0 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Ribosomal_L22 PF00237.14 GAM29213.1 - 1.7e-31 108.2 0.4 2.1e-31 107.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RNF111_N PF15303.1 GAM29213.1 - 0.15 11.5 1.6 0.23 10.9 1.1 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus zf-C3HC4_3 PF13920.1 GAM29214.1 - 1.6e-07 30.9 11.4 3.5e-07 29.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 GAM29214.1 - 5.6e-06 26.2 18.2 1.4e-05 25.0 12.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 GAM29214.1 - 1.9e-05 24.4 17.0 3.9e-05 23.3 11.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 GAM29214.1 - 0.00034 20.2 13.3 0.00097 18.8 9.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Cys_rich_KTR PF14205.1 GAM29214.1 - 0.28 10.6 7.2 0.21 11.0 0.1 2.9 3 0 0 3 3 3 0 Cysteine-rich KTR FdhE PF04216.7 GAM29214.1 - 3.8 7.1 12.2 6.6 6.3 8.5 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-RING_UBOX PF13445.1 GAM29214.1 - 4.7 7.0 12.9 25 4.6 5.4 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 GAM29214.1 - 5 6.7 13.1 20 4.8 9.1 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Oxidored_q6 PF01058.17 GAM29215.1 - 3.6e-22 78.3 0.3 4.6e-22 78.0 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TIG PF01833.19 GAM29216.1 - 7.4e-09 35.4 20.3 6.3e-06 26.0 0.9 4.0 3 1 0 3 3 3 3 IPT/TIG domain DUF4528 PF15031.1 GAM29216.1 - 0.021 14.5 0.2 0.049 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Nop14 PF04147.7 GAM29217.1 - 0.0055 14.7 2.6 0.006 14.5 1.8 1.1 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.13 GAM29217.1 - 0.024 13.8 2.8 0.036 13.2 1.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region TFIIA PF03153.8 GAM29217.1 - 0.06 13.2 8.0 0.09 12.6 5.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4609 PF15382.1 GAM29217.1 - 0.087 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4609) FAM176 PF14851.1 GAM29217.1 - 0.56 9.8 2.4 1.1 8.9 1.7 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 GAM29217.1 - 0.75 9.3 9.4 1.3 8.6 6.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 GAM29217.1 - 0.82 9.4 7.4 1.8 8.3 5.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 GAM29217.1 - 0.94 8.4 5.8 1.9 7.4 4.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 GAM29217.1 - 1 8.8 16.3 1.9 7.9 11.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 GAM29217.1 - 4.5 6.3 11.2 7 5.6 7.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 GAM29217.1 - 4.5 7.6 13.6 10 6.4 9.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 GAM29217.1 - 5.6 7.2 19.0 15 5.9 13.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 GAM29217.1 - 6.2 5.4 22.3 9.8 4.7 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 GAM29217.1 - 9.7 3.9 9.7 14 3.3 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RhoGAP PF00620.22 GAM29218.1 - 7.6e-40 136.0 0.5 7.6e-40 136.0 0.4 2.9 2 1 0 2 2 2 1 RhoGAP domain Cpn60_TCP1 PF00118.19 GAM29219.1 - 1.2e-119 400.0 10.5 1.4e-119 399.9 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bromo_MP PF01573.11 GAM29221.1 - 0.034 13.1 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Bromovirus movement protein GST_C PF00043.20 GAM29222.1 - 7.5e-07 29.0 0.0 1.8e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 GAM29222.1 - 2.9e-06 27.4 0.0 5.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 GAM29222.1 - 8.3e-06 25.6 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 GAM29222.1 - 1.2e-05 25.3 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 GAM29222.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 GAM29222.1 - 0.00038 20.8 0.0 0.00086 19.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF211 PF02680.9 GAM29223.1 - 0.033 13.9 0.3 0.29 10.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized ArCR, COG1888 Ank_2 PF12796.2 GAM29224.1 - 2.2e-07 31.1 0.2 0.056 13.7 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM29224.1 - 0.037 14.5 1.8 5.4 7.6 0.0 4.9 7 0 0 7 7 7 0 Ankyrin repeats (many copies) Mit_ribos_Mrp51 PF11709.3 GAM29224.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Ank_2 PF12796.2 GAM29225.1 - 8.1e-09 35.7 0.7 0.0023 18.2 0.1 2.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM29225.1 - 0.0022 18.4 0.0 5 7.7 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) LIM PF00412.17 GAM29226.1 - 3.8e-23 81.3 33.4 1.7e-09 37.5 3.4 3.8 3 0 0 3 3 3 3 LIM domain DisA_N PF02457.11 GAM29226.1 - 0.0052 15.9 0.0 0.45 9.6 0.0 3.0 2 1 0 3 3 3 1 DisA bacterial checkpoint controller nucleotide-binding WD40 PF00400.27 GAM29227.1 - 4.3e-74 241.9 17.8 2.1e-11 43.2 0.9 7.6 8 0 0 8 8 7 7 WD domain, G-beta repeat Tup_N PF08581.5 GAM29227.1 - 7.5e-22 77.3 8.8 1.5e-21 76.3 6.1 1.5 1 0 0 1 1 1 1 Tup N-terminal PD40 PF07676.7 GAM29227.1 - 1.7e-05 24.3 1.1 5 6.8 0.0 4.9 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 GAM29227.1 - 2.4e-05 23.5 0.3 0.15 11.1 0.0 3.6 3 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 GAM29227.1 - 0.00017 20.0 0.4 0.01 14.1 0.1 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain BBP1_C PF15272.1 GAM29227.1 - 0.0026 17.3 2.1 0.0043 16.6 1.5 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal LXG PF04740.7 GAM29227.1 - 0.0036 17.1 2.1 0.0051 16.6 1.4 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily Nucleoporin_N PF08801.6 GAM29227.1 - 0.0036 16.1 0.4 2 7.0 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 GAM29227.1 - 0.015 13.4 0.7 7.1 4.6 0.2 3.7 1 1 3 4 4 4 0 Nucleoporin Nup120/160 Syntaxin_2 PF14523.1 GAM29227.1 - 0.022 14.7 1.8 0.048 13.6 1.2 1.5 1 0 0 1 1 1 0 Syntaxin-like protein DUF2096 PF09869.4 GAM29227.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Gmad1 PF10647.4 GAM29227.1 - 0.1 12.0 0.0 2.6 7.3 0.0 2.8 1 1 2 3 3 3 0 Lipoprotein LpqB beta-propeller domain DUF2408 PF10303.4 GAM29227.1 - 0.13 12.3 3.0 0.33 11.0 1.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) DUF3312 PF11768.3 GAM29227.1 - 0.13 10.4 0.0 4.6 5.3 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 GAM29227.1 - 0.15 11.4 8.4 51 3.3 0.0 5.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature DUF3450 PF11932.3 GAM29227.1 - 0.25 10.5 7.4 0.29 10.3 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.6 GAM29227.1 - 0.28 9.8 4.3 0.43 9.1 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 GAM29227.1 - 0.35 8.6 1.0 0.49 8.1 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FliJ PF02050.11 GAM29227.1 - 6.2 6.8 12.8 0.34 10.9 5.1 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein ABC2_membrane PF01061.19 GAM29228.1 - 2.1e-77 259.0 62.4 1.8e-42 144.9 15.9 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 GAM29228.1 - 3.6e-44 150.3 0.0 5.1e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_18 PF13238.1 GAM29228.1 - 3.9e-09 36.9 0.0 0.00033 20.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 GAM29228.1 - 9.8e-09 35.5 1.1 0.013 15.4 0.1 4.6 4 1 0 5 5 4 1 AAA domain PDR_assoc PF08370.6 GAM29228.1 - 1.3e-08 34.2 1.9 1.4e-05 24.5 0.3 3.0 2 0 0 2 2 2 2 Plant PDR ABC transporter associated AAA_29 PF13555.1 GAM29228.1 - 4.7e-07 29.2 0.4 0.0024 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 GAM29228.1 - 4.8e-07 30.6 0.0 0.023 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 GAM29228.1 - 8.6e-07 29.1 0.0 0.038 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 GAM29228.1 - 1.4e-06 27.6 0.7 0.00027 20.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 GAM29228.1 - 1.4e-06 28.2 0.0 0.044 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 GAM29228.1 - 1.9e-06 27.1 17.0 1.9e-06 27.1 11.8 3.5 3 2 0 3 3 2 1 ABC-2 family transporter protein PDR_CDR PF06422.7 GAM29228.1 - 2.4e-06 27.1 1.9 0.00029 20.4 0.2 2.9 2 0 0 2 2 2 1 CDR ABC transporter AAA_22 PF13401.1 GAM29228.1 - 3.7e-06 27.1 0.0 0.12 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 GAM29228.1 - 1.7e-05 24.2 0.2 0.08 12.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 GAM29228.1 - 0.00043 20.2 0.1 0.89 9.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain Rad17 PF03215.10 GAM29228.1 - 0.00049 18.9 0.0 0.054 12.1 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 GAM29228.1 - 0.00063 18.4 0.9 0.0099 14.5 0.1 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.18 GAM29228.1 - 0.00096 19.0 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 GAM29228.1 - 0.001 18.9 0.0 0.31 10.9 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.14 GAM29228.1 - 0.0011 18.3 0.7 0.023 14.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 GAM29228.1 - 0.0019 17.5 0.6 1.8 7.7 0.1 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 GAM29228.1 - 0.002 17.7 0.3 0.68 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 GAM29228.1 - 0.0029 17.3 0.1 0.72 9.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 GAM29228.1 - 0.0029 17.7 0.1 5.4 7.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 GAM29228.1 - 0.0036 17.0 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 GAM29228.1 - 0.0049 16.7 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 GAM29228.1 - 0.0061 16.7 0.1 7.5 6.7 0.0 3.2 3 0 0 3 3 2 0 RNA helicase Zeta_toxin PF06414.7 GAM29228.1 - 0.0065 15.5 0.2 2.4 7.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 GAM29228.1 - 0.0066 16.7 0.2 0.046 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 GAM29228.1 - 0.0085 15.1 0.0 1.8 7.4 0.2 3.4 3 1 0 3 3 3 1 AAA ATPase domain UPF0079 PF02367.12 GAM29228.1 - 0.011 15.3 0.9 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 GAM29228.1 - 0.033 13.4 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 GAM29228.1 - 0.049 13.0 2.0 2.4 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 GAM29228.1 - 0.052 13.1 0.0 6.1 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 GAM29228.1 - 0.059 13.0 0.1 20 4.8 0.0 3.1 3 0 0 3 3 3 0 NTPase T2SE PF00437.15 GAM29228.1 - 0.062 12.1 0.2 12 4.7 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein DUF815 PF05673.8 GAM29228.1 - 0.11 11.3 0.4 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 GAM29228.1 - 0.18 11.5 0.6 17 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 GAM29228.1 - 0.22 10.9 0.5 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 GAM29229.1 - 8.9e-07 28.5 1.9 0.0084 15.9 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 GAM29229.1 - 0.00011 21.3 0.2 0.0078 15.3 0.0 2.1 2 0 0 2 2 2 2 CPSF A subunit region PLDc_3 PF13918.1 GAM29230.1 - 1.1e-33 116.1 0.5 8.8e-30 103.4 0.1 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc_2 PF13091.1 GAM29230.1 - 6.5e-32 109.9 0.1 1.1e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 GAM29230.1 - 3.2e-09 36.3 0.3 9.8e-05 22.0 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif ATG13 PF10033.4 GAM29231.1 - 2.6e-21 76.1 2.0 2.6e-21 76.1 1.4 3.1 2 2 0 2 2 2 1 Autophagy-related protein 13 DUF936 PF06075.7 GAM29232.1 - 0.56 9.0 29.3 0.65 8.8 20.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF605 PF04652.11 GAM29232.1 - 2 7.7 39.6 2.6 7.3 27.5 1.1 1 0 0 1 1 1 0 Vta1 like Dsh_C PF12316.3 GAM29235.1 - 0.0052 16.9 14.4 0.0052 16.9 10.0 3.3 3 1 0 3 3 3 1 Segment polarity protein dishevelled (Dsh) C terminal HATPase_c PF02518.21 GAM29236.1 - 1.2e-10 41.0 0.0 2.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zip PF02535.17 GAM29236.1 - 0.011 14.7 0.0 0.011 14.7 0.0 3.3 2 1 1 3 3 3 0 ZIP Zinc transporter Ctr PF04145.10 GAM29236.1 - 0.07 13.1 8.7 18 5.3 0.8 4.3 4 0 0 4 4 4 0 Ctr copper transporter family Neur_chan_memb PF02932.11 GAM29236.1 - 0.27 11.0 15.8 1.3 8.8 0.1 3.0 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 GAM29236.1 - 0.55 9.1 2.7 1.4 7.8 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Response_reg PF00072.19 GAM29237.1 - 5.4e-06 26.3 0.2 8.8e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Ank_2 PF12796.2 GAM29238.1 - 3.2e-17 62.6 1.9 5.2e-08 33.1 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM29238.1 - 6.5e-14 52.0 3.7 6.4e-06 26.5 0.0 4.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29238.1 - 3.4e-13 48.4 4.9 0.00051 20.0 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 GAM29238.1 - 3.2e-12 46.2 4.2 3.9e-05 23.7 0.1 4.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM29238.1 - 5.3e-11 41.7 5.2 0.0043 16.8 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat VPS9 PF02204.13 GAM29238.1 - 3.7e-10 39.7 0.0 9.7e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Glyco_hydro_3 PF00933.16 GAM29239.1 - 3.6e-67 226.4 0.0 4.6e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 GAM29239.1 - 4.9e-47 160.3 0.0 7.1e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 GAM29239.1 - 3.4e-11 42.9 0.0 6.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain RVT_connect PF06815.8 GAM29239.1 - 0.097 12.5 0.1 5.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Reverse transcriptase connection domain DUF605 PF04652.11 GAM29240.1 - 5.7 6.2 11.8 0.94 8.8 6.0 1.3 2 0 0 2 2 2 0 Vta1 like GTP_EFTU PF00009.22 GAM29241.1 - 4.4e-54 182.7 0.3 4.4e-54 182.7 0.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 GAM29241.1 - 4.2e-16 58.5 0.0 1.3e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 GAM29241.1 - 3.4e-10 39.6 0.4 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 GAM29241.1 - 3.7e-09 36.5 0.1 1.7e-08 34.4 0.1 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 GAM29241.1 - 4.8e-08 32.5 0.0 1.8e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G, domain IV IBR PF01485.16 GAM29242.1 - 1.1e-16 60.4 39.4 4.4e-10 39.2 5.5 3.6 3 1 0 3 3 3 3 IBR domain Baculo_p48 PF04878.8 GAM29242.1 - 0.11 11.3 1.7 0.18 10.6 1.2 1.3 1 0 0 1 1 1 0 Baculovirus P48 protein VP_N-CPKC PF11475.3 GAM29242.1 - 0.99 9.0 13.5 0.19 11.2 0.9 3.0 2 1 0 2 2 2 0 Virion protein N terminal domain Abhydro_lipase PF04083.11 GAM29243.1 - 1.1e-23 82.3 0.0 1.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 GAM29243.1 - 6.8e-06 25.8 0.8 0.00025 20.6 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 GAM29243.1 - 0.00015 21.5 0.0 0.00062 19.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF4228 PF14009.1 GAM29243.1 - 0.0061 16.7 0.0 0.0095 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4228) Abhydrolase_6 PF12697.2 GAM29243.1 - 0.022 14.6 0.3 0.17 11.7 0.2 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 GAM29243.1 - 0.026 14.3 0.0 0.074 12.9 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Ecl1 PF12855.2 GAM29243.1 - 0.028 13.7 0.8 0.047 12.9 0.5 1.3 1 0 0 1 1 1 0 Life-span regulatory factor AIG1 PF04548.11 GAM29244.1 - 0.00077 18.6 0.6 0.001 18.2 0.4 1.1 1 0 0 1 1 1 1 AIG1 family Nexin_C PF08628.7 GAM29244.1 - 0.1 12.7 0.1 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Sorting nexin C terminal zf-MYND PF01753.13 GAM29245.1 - 8.9e-07 28.6 18.9 1.9e-06 27.6 13.1 1.6 1 0 0 1 1 1 1 MYND finger Fmp27_WPPW PF10359.4 GAM29245.1 - 0.005 15.3 1.0 0.005 15.3 0.7 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Hira PF07569.6 GAM29245.1 - 0.51 9.5 6.8 1.4 8.0 4.7 1.7 1 0 0 1 1 1 0 TUP1-like enhancer of split SR-25 PF10500.4 GAM29245.1 - 5.3 6.4 23.6 6.2 6.2 7.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FNIP PF05725.7 GAM29246.1 - 2.7e-23 81.6 23.5 0.0059 16.5 0.0 9.4 6 3 4 10 10 10 9 FNIP Repeat FNIP PF05725.7 GAM29247.1 - 6.8e-47 157.1 19.1 9.3e-06 25.5 0.0 9.9 7 2 1 9 9 9 9 FNIP Repeat FNIP PF05725.7 GAM29248.1 - 1.7e-22 79.0 34.9 4.7e-07 29.6 0.5 9.4 5 3 5 10 10 10 8 FNIP Repeat HiaBD2 PF15403.1 GAM29248.1 - 3.5 7.8 10.9 0.18 11.9 1.3 2.5 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) PAXNEB PF05625.6 GAM29249.1 - 1.8e-90 303.4 0.0 2.2e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein DnaJ PF00226.26 GAM29250.1 - 9.3e-19 66.9 0.2 2.2e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_4 PF13717.1 GAM29250.1 - 0.059 13.0 3.4 6.3 6.5 0.1 2.7 2 1 0 2 2 2 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 GAM29250.1 - 0.086 12.6 1.7 0.1 12.4 0.2 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_5 PF13719.1 GAM29250.1 - 0.094 12.3 3.6 9.1 5.9 0.7 2.7 1 1 1 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 GAM29251.1 - 3.2e-07 30.2 0.3 5.8e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 GAM29251.1 - 1e-05 25.5 0.7 1.8e-05 24.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Allexi_40kDa PF05549.6 GAM29251.1 - 0.0017 17.7 4.2 0.0025 17.1 2.9 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein zf-U1 PF06220.7 GAM29251.1 - 0.099 12.2 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger DUF4559 PF15112.1 GAM29251.1 - 0.16 11.1 15.5 0.22 10.6 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) UCH PF00443.24 GAM29251.1 - 0.24 10.5 4.0 0.23 10.5 2.7 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Atg14 PF10186.4 GAM29251.1 - 1.9 7.3 16.9 3.1 6.6 11.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Helitron_like_N PF14214.1 GAM29251.1 - 4 7.1 8.0 1.5 8.5 3.4 1.9 1 1 1 2 2 2 0 Helitron helicase-like domain at N-terminus RNase_HII PF01351.13 GAM29252.1 - 0.073 12.6 5.8 0.11 12.1 4.0 1.2 1 0 0 1 1 1 0 Ribonuclease HII Peptidase_C6 PF00851.13 GAM29252.1 - 0.16 10.5 6.5 0.21 10.1 4.5 1.3 1 0 0 1 1 1 0 Helper component proteinase MitMem_reg PF13012.1 GAM29252.1 - 0.3 11.1 11.0 2.9 8.0 7.6 2.4 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function HD_assoc PF13286.1 GAM29252.1 - 0.35 11.1 6.1 4.5 7.6 0.2 2.3 1 1 1 2 2 2 0 Phosphohydrolase-associated domain Med9 PF07544.8 GAM29252.1 - 0.45 10.2 15.6 0.32 10.7 1.0 3.7 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF896 PF05979.7 GAM29252.1 - 1.1 8.8 7.4 0.69 9.5 3.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) UBN2_3 PF14244.1 GAM29252.1 - 2.7 7.5 8.7 2.3 7.7 3.7 2.5 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type Nup54 PF13874.1 GAM29252.1 - 2.9 7.5 15.3 19 4.9 8.4 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin_1 PF12718.2 GAM29252.1 - 3.6 7.4 21.0 0.23 11.2 10.5 1.9 2 1 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 GAM29252.1 - 4.8 7.0 24.6 0.094 12.6 9.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 GAM29252.1 - 6.5 6.5 18.2 0.15 11.8 3.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 GAM29252.1 - 8.5 5.9 29.8 16 5.0 16.5 2.9 1 1 1 2 2 2 0 IncA protein V_ATPase_I PF01496.14 GAM29252.1 - 8.9 4.0 10.7 12 3.5 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FYVE PF01363.16 GAM29253.1 - 3.4e-19 68.5 7.1 4.2e-19 68.1 4.9 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 GAM29253.1 - 3e-05 23.9 4.7 3.3e-05 23.7 3.3 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger HypA PF01155.14 GAM29253.1 - 0.0023 17.6 5.0 0.0046 16.6 3.5 1.5 1 1 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Kp4 PF09044.5 GAM29253.1 - 0.0025 17.6 0.5 0.003 17.3 0.3 1.1 1 0 0 1 1 1 1 Kp4 zf-RING_2 PF13639.1 GAM29253.1 - 0.022 14.5 3.3 0.029 14.1 2.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 GAM29253.1 - 0.028 14.1 6.7 0.041 13.6 4.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain IBR PF01485.16 GAM29253.1 - 0.1 12.5 10.8 0.3 10.9 7.5 1.8 1 1 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 GAM29253.1 - 0.28 11.1 10.4 0.96 9.3 7.4 1.8 1 1 1 2 2 2 0 AN1-like Zinc finger Lar_restr_allev PF14354.1 GAM29253.1 - 0.45 10.8 4.8 21 5.5 3.3 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-B_box PF00643.19 GAM29253.1 - 0.67 9.8 9.8 1.6 8.6 6.8 1.6 1 1 0 1 1 1 0 B-box zinc finger C1_4 PF07975.7 GAM29253.1 - 1.4 8.9 10.1 15 5.7 0.2 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C3HC4_4 PF15227.1 GAM29253.1 - 2.7 7.9 8.4 0.33 10.8 0.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-DHHC PF01529.15 GAM29253.1 - 3.6 6.9 9.0 3.2 7.1 5.7 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Zn-ribbon_8 PF09723.5 GAM29253.1 - 4.8 7.2 9.1 1.1e+02 2.8 6.3 2.9 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 GAM29253.1 - 5.1 6.7 11.9 3.6e+02 0.8 8.2 2.9 1 1 0 1 1 1 0 zinc-ribbon domain TPR_11 PF13414.1 GAM29254.1 - 1.7e-23 82.0 16.2 2.8e-10 39.6 0.1 7.5 7 0 0 7 7 7 4 TPR repeat TPR_1 PF00515.23 GAM29254.1 - 3.7e-21 73.7 15.6 8.8e-06 25.1 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 GAM29254.1 - 1.8e-18 64.8 21.4 8e-05 22.2 0.0 10.3 11 0 0 11 11 11 3 Tetratricopeptide repeat Apc3 PF12895.2 GAM29254.1 - 5e-17 61.8 10.5 2.7e-12 46.6 0.9 6.2 5 2 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 GAM29254.1 - 3.1e-15 55.8 4.3 1.3e-09 37.8 0.6 7.6 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 GAM29254.1 - 3.1e-14 51.5 0.1 0.00052 19.6 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 GAM29254.1 - 1.9e-13 50.7 0.0 1.5e-07 31.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM29254.1 - 1e-12 46.8 10.9 0.00041 19.9 0.0 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 GAM29254.1 - 1.2e-10 41.0 0.4 0.02 15.4 0.0 6.1 5 2 2 7 7 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 GAM29254.1 - 8.5e-10 38.8 0.2 0.16 12.3 0.0 6.2 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 GAM29254.1 - 1.3e-09 37.5 13.3 0.0023 17.9 0.0 8.4 10 1 1 11 11 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 GAM29254.1 - 8.5e-08 31.8 0.5 0.02 14.7 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.7 GAM29254.1 - 4.6e-06 26.2 7.0 0.0048 16.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM29254.1 - 8.4e-06 25.9 8.0 0.18 12.3 0.0 6.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM29254.1 - 0.09 12.9 0.0 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat APC8 PF04049.8 GAM29254.1 - 0.14 11.8 0.1 0.14 11.8 0.1 3.8 2 1 1 3 3 3 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_4 PF07721.9 GAM29254.1 - 0.89 10.1 2.6 3.3 8.3 0.0 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat PLAC8 PF04749.12 GAM29255.1 - 2.5e-16 60.1 19.8 3.1e-16 59.8 13.7 1.1 1 0 0 1 1 1 1 PLAC8 family Pkinase PF00069.20 GAM29256.1 - 1.8e-58 197.7 0.0 4e-58 196.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29256.1 - 1.2e-49 168.6 0.0 2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 GAM29256.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ndc1_Nup PF09531.5 GAM29256.1 - 0.23 9.8 2.9 0.33 9.3 2.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_membrane PF00664.18 GAM29257.1 - 1.5e-114 382.0 24.7 1.3e-57 195.3 6.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 GAM29257.1 - 8.5e-70 233.3 0.0 1.6e-33 115.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 GAM29257.1 - 2e-15 56.6 0.0 8.1e-07 28.4 0.0 3.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 GAM29257.1 - 2.3e-10 39.6 2.4 0.00028 19.6 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 GAM29257.1 - 6e-09 36.2 1.8 0.052 13.5 0.0 4.8 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 GAM29257.1 - 3.1e-06 26.6 2.4 0.041 13.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 GAM29257.1 - 3.1e-06 26.9 2.3 0.057 13.3 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 GAM29257.1 - 4.5e-06 25.9 0.0 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 GAM29257.1 - 9.8e-06 25.6 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 GAM29257.1 - 3.6e-05 23.9 0.2 0.68 10.0 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 GAM29257.1 - 0.00097 19.9 0.2 9.2 7.1 0.1 4.0 3 1 0 3 3 3 1 AAA domain SR-25 PF10500.4 GAM29257.1 - 0.014 14.9 14.0 0.027 13.9 9.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_5 PF07728.9 GAM29257.1 - 0.047 13.4 0.9 24 4.6 0.0 3.8 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 GAM29257.1 - 0.12 12.6 3.7 9.6 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain SAM_1 PF00536.25 GAM29259.1 - 0.028 14.5 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ABC2_membrane_3 PF12698.2 GAM29260.1 - 3.7 6.4 11.1 3.4 6.5 2.2 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Dicty_REP PF05086.7 GAM29260.1 - 5.4 4.6 36.2 0.17 9.6 5.7 2.4 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DnaJ PF00226.26 GAM29262.1 - 5.8e-07 29.1 0.1 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Lin-8 PF03353.10 GAM29262.1 - 0.01 15.1 2.5 0.014 14.6 1.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Gag_spuma PF03276.9 GAM29262.1 - 0.27 9.5 12.6 0.39 8.9 8.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Spc7_N PF15402.1 GAM29262.1 - 0.63 7.9 11.9 0.85 7.5 8.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CobT PF06213.7 GAM29262.1 - 0.85 8.6 9.7 1.2 8.2 6.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 GAM29262.1 - 1 8.5 8.5 1.5 8.0 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 GAM29262.1 - 4 7.0 14.4 6.2 6.4 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.20 GAM29264.1 - 0.17 10.9 0.7 0.18 10.8 0.5 1.2 1 0 0 1 1 1 0 Protein kinase domain RVP PF00077.15 GAM29268.1 - 1.6e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 GAM29268.1 - 0.00012 22.0 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 GAM29268.1 - 0.0016 18.8 0.1 0.0053 17.2 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 GAM29268.1 - 0.0035 17.2 0.8 0.0072 16.2 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 GAM29268.1 - 0.025 14.2 0.7 0.062 12.9 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 GAM29270.1 - 1.7e-13 50.7 0.0 3.9e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain TraV PF09676.5 GAM29271.1 - 0.1 13.2 0.6 0.14 12.8 0.4 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) F1F0-ATPsyn_F PF10791.4 GAM29272.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi TPR_11 PF13414.1 GAM29273.1 - 5.3e-11 42.0 5.4 1.8e-07 30.6 0.1 4.3 3 2 1 5 5 5 2 TPR repeat Apc3 PF12895.2 GAM29273.1 - 2e-08 34.2 4.0 0.0004 20.4 0.4 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 GAM29273.1 - 7.1e-06 25.5 0.4 2.6 8.1 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 GAM29273.1 - 7.6e-06 25.3 1.0 0.42 10.3 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 GAM29273.1 - 3.5e-05 23.6 5.8 0.0074 16.2 0.2 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 GAM29273.1 - 8.2e-05 22.8 3.3 0.072 13.4 0.0 4.8 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 GAM29273.1 - 9e-05 21.6 2.0 0.0048 15.9 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 GAM29273.1 - 0.0019 18.5 2.1 0.89 10.1 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 GAM29273.1 - 0.0021 18.6 0.1 0.71 10.6 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 GAM29273.1 - 0.0031 17.4 1.9 0.02 14.8 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 GAM29273.1 - 0.0039 17.2 2.9 9.8 6.3 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 GAM29273.1 - 0.004 17.6 0.0 15 6.5 0.0 5.1 3 1 3 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 GAM29273.1 - 0.0069 16.1 0.1 2.6 8.0 0.0 3.6 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 GAM29273.1 - 0.01 15.5 0.3 90 3.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.7 GAM29273.1 - 0.042 13.4 1.6 0.48 10.0 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF627) TPR_17 PF13431.1 GAM29273.1 - 0.063 13.4 0.1 22 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 GAM29273.1 - 0.099 12.5 2.8 3.7 7.4 0.0 3.7 3 2 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF3123 PF11321.3 GAM29273.1 - 2 8.7 7.1 5.8 7.2 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) MFS_1 PF07690.11 GAM29274.1 - 3.6e-35 121.3 17.5 8.2e-35 120.1 12.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 GAM29274.1 - 2.4e-13 49.5 6.1 2.4e-13 49.5 4.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 GAM29274.1 - 0.0021 16.3 0.5 0.0021 16.3 0.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Syndecan PF01034.15 GAM29274.1 - 0.12 12.0 0.0 0.71 9.5 0.0 2.4 2 1 1 3 3 3 0 Syndecan domain COX5B PF01215.14 GAM29275.1 - 5.7e-38 129.6 0.0 7e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-LYAR PF08790.6 GAM29275.1 - 0.55 9.9 2.6 0.47 10.2 0.5 1.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Herpes_BLLF1 PF05109.8 GAM29276.1 - 0.0045 15.0 21.6 0.0052 14.8 15.0 1.3 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) CDC27 PF09507.5 GAM29276.1 - 0.042 13.0 30.7 0.053 12.7 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.17 GAM29276.1 - 0.78 8.6 17.8 2.7 6.9 0.4 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Med15 PF09606.5 GAM29276.1 - 1.5 6.9 39.6 2.4 6.2 27.5 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SdpI PF13630.1 GAM29277.1 - 7.4 6.3 7.1 8.3 6.2 4.9 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family KH_3 PF13014.1 GAM29278.1 - 0.12 12.0 0.2 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 KH domain Pkinase PF00069.20 GAM29279.1 - 1.1e-73 247.6 0.0 1.1e-73 247.6 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29279.1 - 2e-34 118.8 0.0 3.6e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM29279.1 - 2.7e-07 29.8 0.0 4.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM29279.1 - 6.6e-05 22.0 0.0 0.00014 21.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 GAM29279.1 - 0.00016 21.4 0.0 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 GAM29279.1 - 0.01 15.2 0.6 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL adh_short PF00106.20 GAM29280.1 - 9e-18 64.7 0.0 1.7e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM29280.1 - 8.3e-07 28.8 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 GAM29280.1 - 0.002 17.2 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short_C2 PF13561.1 GAM29280.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 GAM29280.1 - 0.004 16.6 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FNIP PF05725.7 GAM29281.1 - 2.5e-48 161.7 9.1 2.5e-14 52.9 0.3 5.5 5 0 0 5 5 5 5 FNIP Repeat LMWPc PF01451.16 GAM29282.1 - 4.3e-31 108.0 0.0 7.1e-30 104.1 0.0 2.1 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF4611 PF15387.1 GAM29283.1 - 0.039 14.0 14.8 0.052 13.6 3.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 GAM29283.1 - 0.1 12.9 11.8 0.68 10.2 3.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.6 GAM29283.1 - 0.43 9.8 24.2 0.2 10.8 8.6 2.1 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) FAM177 PF14774.1 GAM29283.1 - 0.6 10.0 12.0 0.29 11.0 2.8 2.3 2 0 0 2 2 2 0 FAM177 family Nucleoplasmin PF03066.10 GAM29283.1 - 8.8 5.8 20.0 0.41 10.1 1.8 2.3 2 1 0 2 2 2 0 Nucleoplasmin Peptidase_C1 PF00112.18 GAM29285.1 - 2.2e-75 253.2 3.6 3.3e-75 252.7 2.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 GAM29285.1 - 8.6e-13 48.3 6.6 8.6e-13 48.3 4.6 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 GAM29285.1 - 0.0016 17.0 2.0 0.013 14.0 0.3 2.3 2 0 0 2 2 2 1 Peptidase C1-like family DUF2457 PF10446.4 GAM29286.1 - 0.0017 17.1 24.7 0.0017 17.1 17.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Mucin PF01456.12 GAM29286.1 - 1.7 8.4 43.4 0.39 10.4 18.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein MCPVI PF02993.9 GAM29286.1 - 3.9 7.5 20.4 12 6.0 0.3 2.5 2 0 0 2 2 2 0 Minor capsid protein VI Acyl-CoA_dh_1 PF00441.19 GAM29287.1 - 1.1e-42 145.7 0.1 1.8e-42 144.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 GAM29287.1 - 2.2e-38 131.2 0.0 4.4e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 GAM29287.1 - 5.1e-22 77.1 0.2 1.1e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 GAM29287.1 - 6.3e-13 49.1 0.0 3.4e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 GAM29287.1 - 0.013 14.9 0.1 0.059 12.7 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pox_LP_H2 PF03356.10 GAM29287.1 - 0.11 12.1 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral late protein H2 ALG3 PF05208.8 GAM29288.1 - 2.4e-49 168.5 35.1 3.5e-47 161.4 24.3 2.3 1 1 0 1 1 1 1 ALG3 protein Me-amine-dh_H PF06433.6 GAM29288.1 - 0.0099 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) ERG4_ERG24 PF01222.12 GAM29289.1 - 1e-97 327.4 20.9 1.2e-97 327.2 14.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2530 PF10745.4 GAM29289.1 - 0.031 14.2 0.2 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) HSP70 PF00012.15 GAM29290.1 - 3.4e-128 428.2 3.4 4.6e-128 427.7 2.3 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 GAM29290.1 - 6.5e-08 31.5 1.8 0.0071 14.9 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 GAM29290.1 - 0.00019 21.0 0.0 0.00041 20.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_C39 PF03412.10 GAM29290.1 - 0.13 12.0 0.2 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase C39 family Y_phosphatase2 PF03162.8 GAM29291.1 - 1.7e-42 144.5 0.0 3e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 GAM29291.1 - 0.00071 19.8 0.1 0.018 15.3 0.0 2.7 2 1 0 3 3 3 1 Tyrosine phosphatase family RhoGEF PF00621.15 GAM29292.1 - 8e-37 126.8 5.7 2.2e-36 125.4 4.0 1.8 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.26 GAM29293.1 - 1.5e-38 131.1 0.2 3.4e-19 68.8 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain Cortex-I_coil PF09304.5 GAM29293.1 - 9.6e-32 109.2 20.2 9.6e-32 109.2 14.0 2.6 4 0 0 4 4 4 1 Cortexillin I, coiled coil CAMSAP_CH PF11971.3 GAM29293.1 - 6.2e-09 35.3 0.0 2.4e-06 27.0 0.0 2.9 2 1 0 2 2 2 1 CAMSAP CH domain DUF1217 PF06748.7 GAM29293.1 - 0.0066 16.5 0.7 0.018 15.1 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1217) Reo_sigmaC PF04582.7 GAM29293.1 - 0.17 11.0 0.4 0.41 9.7 0.3 1.7 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Filament PF00038.16 GAM29293.1 - 0.18 11.2 21.2 0.049 13.1 8.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein LMBR1 PF04791.11 GAM29293.1 - 4.3 5.7 4.8 6.7 5.1 3.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF501 PF04417.7 GAM29293.1 - 5.3 6.9 9.2 0.21 11.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF501) FUSC PF04632.7 GAM29293.1 - 7.5 4.8 5.5 10 4.3 3.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SapB_2 PF03489.12 GAM29294.1 - 8.9e-35 118.2 17.7 3.1e-08 33.4 0.0 5.9 5 0 0 5 5 5 5 Saposin-like type B, region 2 SapB_1 PF05184.10 GAM29294.1 - 1.1e-18 66.5 21.7 1.8e-05 24.4 0.1 6.1 5 0 0 5 5 5 5 Saposin-like type B, region 1 GDNF PF02351.11 GAM29294.1 - 6 7.4 11.0 1.8 9.0 0.7 3.8 3 0 0 3 3 3 0 GDNF/GAS1 domain FNIP PF05725.7 GAM29295.1 - 1.6e-30 104.7 1.6 1.8e-09 37.4 0.0 3.5 2 1 1 3 3 3 3 FNIP Repeat Cna_B PF05738.8 GAM29297.1 - 6.9e-05 22.5 0.1 6.9e-05 22.5 0.1 2.5 3 0 0 3 3 3 1 Cna protein B-type domain Bt_P21 PF05560.6 GAM29297.1 - 0.079 12.3 0.6 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacillus thuringiensis P21 molecular chaperone protein DUF4557 PF15101.1 GAM29298.1 - 6.8 6.4 14.8 0.11 12.2 4.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RNA_pol_Rpb5_C PF01191.14 GAM29299.1 - 5.6e-35 118.7 2.2 7.8e-35 118.3 0.9 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 GAM29299.1 - 3.1e-20 72.3 0.5 1e-19 70.7 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.9 GAM29299.1 - 0.11 12.5 1.1 0.21 11.6 0.8 1.5 1 0 0 1 1 1 0 Sof1-like domain ENTH PF01417.15 GAM29300.1 - 3e-43 146.6 0.1 4.6e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 GAM29300.1 - 0.082 11.5 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 ANTH domain Sec7 PF01369.15 GAM29301.1 - 8.1e-44 149.5 0.3 1.2e-43 148.9 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 GAM29301.1 - 4e-19 68.7 1.2 7.6e-19 67.8 0.8 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 GAM29301.1 - 1e-06 28.9 1.6 2.5e-06 27.7 1.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 GAM29301.1 - 0.0021 18.1 1.4 0.054 13.5 1.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 GAM29301.1 - 0.13 12.4 1.1 4.2 7.5 0.8 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain MIT PF04212.13 GAM29302.1 - 4.9e-40 135.2 13.9 2.4e-15 56.1 1.2 3.2 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 GAM29302.1 - 0.00039 19.9 6.7 0.64 9.6 0.1 3.7 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 GAM29302.1 - 0.005 16.6 9.4 0.57 10.2 0.2 5.0 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 GAM29302.1 - 0.0094 15.6 2.0 7.7 6.5 0.1 3.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 GAM29302.1 - 0.013 15.0 9.1 0.36 10.5 0.2 4.9 4 1 2 6 6 6 0 Tetratricopeptide repeat Use1 PF09753.4 GAM29302.1 - 0.077 12.4 0.9 0.26 10.6 0.3 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 TPR_8 PF13181.1 GAM29302.1 - 0.12 12.2 5.0 15 5.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM29302.1 - 0.2 11.6 7.2 33 4.5 0.0 4.2 3 2 1 4 4 4 0 Tetratricopeptide repeat NAD_binding_2 PF03446.10 GAM29303.1 - 2.8e-55 186.5 0.2 3.8e-55 186.1 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 GAM29303.1 - 2.8e-35 121.0 0.0 4.9e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 GAM29303.1 - 1.9e-09 36.9 0.0 3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 GAM29303.1 - 2.3e-09 37.5 0.1 7.4e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 GAM29303.1 - 8e-07 28.5 0.1 1.3e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 GAM29303.1 - 1.3e-06 27.9 0.3 6.1e-05 22.4 0.2 2.6 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 GAM29303.1 - 1.5e-05 24.6 0.2 7.1e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 GAM29303.1 - 0.00029 20.8 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 GAM29303.1 - 0.00032 20.1 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 GAM29303.1 - 0.0053 16.5 0.3 0.025 14.3 0.2 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OCD_Mu_crystall PF02423.10 GAM29303.1 - 0.027 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.17 GAM29303.1 - 0.045 14.2 0.2 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 GAM29303.1 - 0.046 13.9 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 GAM29303.1 - 0.087 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Coiled PF05710.7 GAM29303.1 - 1.3 9.5 6.8 0.35 11.3 2.0 2.2 2 1 0 2 2 1 0 Coiled coil Oxysterol_BP PF01237.13 GAM29304.1 - 2.1e-57 194.2 0.3 2.9e-57 193.7 0.2 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Flavokinase PF01687.12 GAM29305.1 - 1.8e-33 115.0 0.0 2.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase BRO1 PF03097.13 GAM29306.1 - 2.8e-96 322.5 11.7 2.8e-96 322.5 8.1 2.4 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 GAM29306.1 - 2.1e-66 223.9 22.4 2.1e-66 223.9 15.5 3.1 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV rve_2 PF13333.1 GAM29306.1 - 0.8 9.8 5.1 1.1 9.4 0.1 3.7 4 0 0 4 4 4 0 Integrase core domain MitMem_reg PF13012.1 GAM29306.1 - 3 7.9 17.6 0.33 11.0 1.2 4.7 2 1 1 4 4 4 0 Maintenance of mitochondrial structure and function LIM PF00412.17 GAM29307.1 - 8.9e-30 102.5 41.5 1.6e-11 44.1 8.7 3.3 3 0 0 3 3 3 3 LIM domain WH2 PF02205.15 GAM29308.1 - 3.1e-09 36.1 0.2 6.1e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 WH2 motif Thymosin PF01290.15 GAM29308.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Thymosin beta-4 family Pkinase PF00069.20 GAM29309.1 - 5.8e-64 215.7 0.0 1.4e-63 214.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29309.1 - 7.7e-49 166.0 0.0 1.2e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM29309.1 - 0.00051 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Ras PF00071.17 GAM29310.1 - 9.2e-35 119.4 0.2 1.1e-34 119.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 GAM29310.1 - 1.4e-23 83.6 0.1 5.7e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 GAM29310.1 - 3.5e-08 32.8 0.1 3.9e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 GAM29310.1 - 8e-07 28.4 0.2 9.7e-07 28.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 GAM29310.1 - 0.0005 19.5 0.1 0.0037 16.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 GAM29310.1 - 0.0081 16.1 0.0 0.011 15.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 GAM29310.1 - 0.009 14.7 0.1 0.028 13.1 0.0 1.8 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.4 GAM29310.1 - 0.014 14.9 0.2 0.034 13.6 0.2 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 GAM29310.1 - 0.055 12.6 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Robl_LC7 PF03259.12 GAM29311.1 - 9e-09 34.7 0.1 2.1e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Roadblock/LC7 domain PseudoU_synth_1 PF01416.15 GAM29312.1 - 3.4e-23 82.0 0.1 2.2e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 GAM29312.1 - 0.0076 15.7 0.0 0.023 14.2 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2344) Sigma70_ner PF04546.8 GAM29312.1 - 1.1 8.8 5.5 2.3 7.7 3.8 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Alk_phosphatase PF00245.15 GAM29313.1 - 2.8e-85 286.5 4.2 8.4e-85 284.9 2.9 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 GAM29313.1 - 0.00013 21.4 2.2 0.00032 20.1 0.7 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily ETRAMP PF09716.5 GAM29313.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Metallophos PF00149.23 GAM29313.1 - 0.1 11.9 0.3 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase PALP PF00291.20 GAM29314.1 - 4.9e-43 147.5 0.0 3.8e-42 144.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Wbp11 PF09429.5 GAM29315.1 - 2.2e-12 46.7 8.9 2.2e-12 46.7 6.2 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 DUF106 PF01956.11 GAM29315.1 - 0.12 11.9 2.3 2.6 7.5 1.6 2.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 Uds1 PF15456.1 GAM29315.1 - 7.2 6.6 9.3 0.89 9.5 2.1 2.0 2 0 0 2 2 2 0 Up-regulated During Septation RhoGEF PF00621.15 GAM29316.1 - 2.8e-40 138.1 0.6 2.8e-40 138.1 0.4 2.5 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 GAM29316.1 - 1.6e-05 25.0 0.6 0.00012 22.2 0.0 2.6 2 1 0 2 2 2 1 PH domain CH PF00307.26 GAM29317.1 - 2.4e-32 111.2 35.9 3e-14 52.9 0.1 8.1 8 1 0 9 9 9 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 GAM29317.1 - 3.7e-07 29.7 4.3 0.0079 15.8 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain Matrilin_ccoil PF10393.4 GAM29317.1 - 0.033 13.5 0.1 0.033 13.5 0.1 5.2 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin DIL PF01843.14 GAM29318.1 - 5e-22 77.7 4.1 1.6e-21 76.1 2.8 2.0 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.4 GAM29318.1 - 4.3e-19 68.4 2.9 1.4e-18 66.7 2.0 1.9 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_MLP1_2 PF07926.7 GAM29318.1 - 0.0015 18.2 3.9 0.0015 18.2 2.7 3.7 2 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein NYD-SP28_assoc PF14775.1 GAM29318.1 - 1.1 9.0 9.5 5.6 6.7 1.9 3.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain GAS PF13851.1 GAM29318.1 - 2.8 7.0 39.1 0.83 8.8 8.5 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_12 PF13087.1 GAM29319.1 - 2.7e-49 167.2 0.2 5.8e-49 166.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 GAM29319.1 - 8.2e-26 91.0 4.5 1.2e-25 90.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 GAM29319.1 - 1.6e-11 44.1 0.0 0.014 14.9 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2439 PF10382.4 GAM29319.1 - 5.8e-10 39.2 1.5 2.7e-09 37.1 1.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) zf-GRF PF06839.7 GAM29319.1 - 6.4e-08 32.4 1.3 2.1e-07 30.7 0.9 1.9 1 0 0 1 1 1 1 GRF zinc finger UvrD_C_2 PF13538.1 GAM29319.1 - 1.4e-06 28.3 0.0 4.7e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 GAM29319.1 - 0.00063 19.3 0.0 0.072 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 GAM29319.1 - 0.00068 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 GAM29319.1 - 0.082 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyt-b5 PF00173.23 GAM29320.1 - 1.2e-22 79.4 0.1 1.3e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mst1_SARAH PF11629.3 GAM29321.1 - 0.11 12.3 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 SapB_2 PF03489.12 GAM29322.1 - 0.0025 17.7 0.4 0.46 10.5 0.0 2.6 2 0 0 2 2 2 2 Saposin-like type B, region 2 SPA PF08616.5 GAM29323.1 - 1.1e-12 47.6 0.1 2.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 GAM29323.1 - 2.1e-08 33.0 1.5 1.1e-07 30.7 1.0 2.0 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 GAM29323.1 - 2.6e-06 27.2 0.9 9.1e-06 25.5 0.6 2.0 1 1 0 1 1 1 1 DENN (AEX-3) domain DUF2347 PF09804.4 GAM29323.1 - 0.007 15.6 4.9 0.0094 15.2 1.2 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) RuvA_N PF01330.16 GAM29324.1 - 0.021 14.5 0.4 0.033 13.9 0.3 1.4 1 1 0 1 1 1 0 RuvA N terminal domain GSAP-16 PF14959.1 GAM29325.1 - 6.3e-24 83.9 0.5 6.3e-24 83.9 0.4 2.2 2 0 0 2 2 2 1 gamma-Secretase-activating protein C-term WD40 PF00400.27 GAM29326.1 - 3e-08 33.2 7.8 0.0084 15.9 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Cleaved_Adhesin PF07675.6 GAM29326.1 - 0.052 13.1 0.4 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Cleaved Adhesin Domain RepA_N PF06970.6 GAM29326.1 - 0.099 12.4 0.6 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus CDC45 PF02724.9 GAM29327.1 - 0.095 10.7 3.2 0.17 9.8 2.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 GAM29328.1 - 1.1e-79 268.5 102.3 1.2e-65 222.3 14.0 3.0 1 1 2 3 3 3 3 Vta1 like RNB PF00773.14 GAM29330.1 - 5.4e-88 295.3 0.3 1.7e-87 293.7 0.0 1.9 2 0 0 2 2 2 1 RNB domain ATG27 PF09451.5 GAM29331.1 - 1.3e-06 27.8 1.9 1.3e-06 27.8 1.3 1.8 1 1 1 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 GAM29331.1 - 1.9e-06 27.1 0.1 1.9e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.1 GAM29331.1 - 3.6e-05 23.2 0.4 4.8e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein TPR_11 PF13414.1 GAM29332.1 - 2.7e-34 116.6 19.6 3.4e-07 29.8 0.2 6.3 3 3 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 GAM29332.1 - 1.4e-26 90.2 20.2 5.6e-06 25.8 0.4 8.8 8 1 1 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.26 GAM29332.1 - 5.6e-23 80.4 15.2 9.9e-23 79.6 3.8 3.6 3 1 0 3 3 3 1 DnaJ domain TPR_1 PF00515.23 GAM29332.1 - 1e-21 75.5 21.8 6.6e-07 28.6 0.4 8.7 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 GAM29332.1 - 1.6e-20 73.2 2.6 0.00058 20.4 0.0 5.9 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 GAM29332.1 - 1.5e-17 61.9 16.3 0.00057 19.4 0.0 7.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 GAM29332.1 - 3.3e-15 56.1 14.8 1.3e-05 25.4 0.4 5.9 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 GAM29332.1 - 3.6e-14 52.4 14.2 0.0014 18.5 0.2 6.1 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 GAM29332.1 - 3.7e-14 51.9 10.3 0.0039 17.6 0.0 6.9 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 GAM29332.1 - 4.5e-09 36.0 0.9 0.00036 20.3 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 GAM29332.1 - 3.3e-08 33.5 11.3 0.00033 20.7 0.1 4.5 2 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 GAM29332.1 - 1.8e-06 27.7 7.0 0.51 10.2 0.0 5.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 GAM29332.1 - 6.4e-06 26.2 12.3 0.059 13.8 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 GAM29332.1 - 1.1e-05 25.6 6.5 0.17 12.1 0.1 3.7 1 1 2 3 3 3 2 Alkyl sulfatase dimerisation TPR_17 PF13431.1 GAM29332.1 - 0.00047 20.1 16.2 0.14 12.4 0.1 7.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 GAM29332.1 - 0.00059 19.9 8.2 0.61 10.2 0.1 4.7 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 GAM29332.1 - 0.0011 18.5 7.3 1.4 8.9 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TINF2_N PF14973.1 GAM29332.1 - 0.015 15.4 1.7 0.038 14.1 0.2 2.5 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus BTAD PF03704.12 GAM29332.1 - 0.092 13.0 1.4 2.2 8.6 0.0 3.0 3 1 0 3 3 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 GAM29332.1 - 9.6 6.2 7.4 74 3.4 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.18 GAM29333.1 - 2.3e-63 213.9 0.1 2.3e-63 213.9 0.1 3.2 3 1 0 3 3 3 1 Kinesin motor domain DUF2968 PF11180.3 GAM29333.1 - 6.8e-05 22.3 10.3 6.8e-05 22.3 7.2 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2968) Myosin_tail_1 PF01576.14 GAM29333.1 - 0.04 11.6 30.0 0.096 10.3 20.8 1.5 1 1 0 1 1 1 0 Myosin tail NPV_P10 PF05531.7 GAM29333.1 - 0.29 11.4 11.0 13 6.1 0.4 5.3 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 GAM29333.1 - 2.1 8.1 19.1 1.7 8.4 1.7 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) Rootletin PF15035.1 GAM29333.1 - 4.1 7.3 37.0 0.38 10.7 5.4 3.7 4 0 0 4 4 4 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 GAM29333.1 - 6.4 5.9 33.8 0.35 10.0 15.1 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding SAM_1 PF00536.25 GAM29334.1 - 0.0024 17.9 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 GAM29334.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SET PF00856.23 GAM29335.1 - 0.016 15.5 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 SET domain VKOR PF07884.9 GAM29338.1 - 0.067 13.0 2.2 0.095 12.5 1.5 1.4 1 1 0 1 1 1 0 Vitamin K epoxide reductase family Pilt PF15453.1 GAM29341.1 - 0.18 11.4 4.0 0.29 10.7 2.8 1.3 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Peptidase_C39_2 PF13529.1 GAM29343.1 - 1.5e-10 41.6 0.0 4.1e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase_C39 like family Guanylate_cyc_2 PF09778.4 GAM29343.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Guanylylate cyclase Transpep_BrtH PF14399.1 GAM29343.1 - 0.062 12.5 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase SH3BGR PF04908.10 GAM29344.1 - 1.9e-15 56.5 0.1 2.8e-15 56.0 0.1 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 GAM29344.1 - 1.2e-10 41.2 0.0 1.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 GAM29344.1 - 0.075 13.2 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RhoGAP PF00620.22 GAM29345.1 - 4.5e-36 123.7 0.3 1.4e-35 122.1 0.2 1.8 1 0 0 1 1 1 1 RhoGAP domain BAR_2 PF10455.4 GAM29345.1 - 6.3e-05 22.0 10.9 6.7e-05 21.9 6.7 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GAS PF13851.1 GAM29345.1 - 0.0048 16.1 3.3 0.0048 16.1 2.3 3.2 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding IncA PF04156.9 GAM29345.1 - 6.2 6.3 11.5 0.49 9.9 1.6 2.5 2 0 0 2 2 2 0 IncA protein DSPc PF00782.15 GAM29346.1 - 5.5e-12 45.4 5.9 3e-06 26.8 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain tRNA-synt_1 PF00133.17 GAM29347.1 - 1.3e-12 46.5 0.0 1.6e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 GAM29347.1 - 2e-10 39.9 0.0 2.5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 GAM29348.1 - 1.1e-36 126.0 0.0 2.7e-36 124.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 GAM29348.1 - 6.8e-13 48.6 0.6 4.4e-12 46.0 0.4 2.2 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 GAM29348.1 - 6e-11 41.6 0.2 4.7e-08 32.0 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 GAM29348.1 - 6.6e-06 25.4 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 GAM29348.1 - 0.028 13.1 0.1 0.63 8.6 0.0 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (K) PhyH PF05721.8 GAM29349.1 - 2.6e-07 30.8 0.0 6.7e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 GAM29349.1 - 0.00038 19.0 0.4 2.5 6.4 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) NIF PF03031.13 GAM29350.1 - 5.2e-23 81.4 1.1 5.2e-23 81.4 0.7 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 GAM29350.1 - 8.1e-06 25.1 0.0 2.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF1938 PF09153.5 GAM29350.1 - 0.14 12.0 0.2 19 5.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Flg_new PF09479.5 GAM29350.1 - 1.1 9.3 8.4 0.72 9.9 2.2 2.7 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Arf PF00025.16 GAM29351.1 - 1.9e-77 258.4 0.1 2.3e-77 258.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 GAM29351.1 - 1.4e-14 53.7 0.0 1.6e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 GAM29351.1 - 2e-12 46.8 0.0 2.2e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 GAM29351.1 - 3.5e-12 45.7 2.7 1.6e-09 36.9 0.5 2.4 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 GAM29351.1 - 7.5e-12 44.8 0.0 8.7e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 GAM29351.1 - 5e-08 33.4 0.0 8.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 GAM29351.1 - 1.7e-05 24.7 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 GAM29351.1 - 0.0057 15.7 0.5 0.018 14.1 0.4 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 GAM29351.1 - 0.012 15.0 0.3 0.067 12.6 0.2 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 GAM29351.1 - 0.089 12.6 0.2 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 GAM29351.1 - 0.18 11.4 0.7 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Pkinase_Tyr PF07714.12 GAM29352.1 - 5.1e-59 199.4 0.0 7.5e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 GAM29352.1 - 5.2e-53 179.8 0.0 7.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 GAM29352.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.9 GAM29352.1 - 0.00025 21.0 0.1 0.0006 19.8 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain APH PF01636.18 GAM29352.1 - 0.016 14.9 0.2 0.2 11.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3439 PF11921.3 GAM29352.1 - 0.053 13.2 2.1 0.12 12.1 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 GAM29352.1 - 0.12 10.3 6.3 0.17 9.8 4.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_5 PF12695.2 GAM29353.1 - 3.9e-17 62.3 0.0 5.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 GAM29353.1 - 6e-14 52.4 0.0 8.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 GAM29353.1 - 1.2e-07 31.1 0.0 0.0054 15.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 GAM29353.1 - 3e-05 23.5 0.6 0.0025 17.2 0.0 2.8 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 GAM29353.1 - 0.00082 18.3 0.0 0.0011 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 GAM29353.1 - 0.0019 17.7 0.2 2 7.9 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 GAM29353.1 - 0.0032 16.7 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family PAE PF03283.8 GAM29353.1 - 0.012 14.2 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase Peptidase_S15 PF02129.13 GAM29353.1 - 0.016 14.6 0.0 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 GAM29353.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2974 PF11187.3 GAM29353.1 - 0.06 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.7 GAM29353.1 - 0.072 11.5 0.1 1.9 6.9 0.0 2.6 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 GAM29353.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pterin_4a PF01329.14 GAM29354.1 - 2e-23 81.9 0.0 2.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF1566 PF07603.6 GAM29354.1 - 0.072 12.8 0.1 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1566) Cullin PF00888.17 GAM29355.1 - 6.9e-121 404.6 24.7 6.9e-121 404.6 17.1 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 GAM29355.1 - 2.4e-26 91.3 2.6 6.1e-26 90.0 1.8 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS PF00615.14 GAM29355.1 - 0.034 14.2 9.4 0.5 10.4 1.9 3.7 3 1 0 3 3 3 0 Regulator of G protein signaling domain GAT PF03127.9 GAM29355.1 - 0.31 11.0 5.6 1.2 9.1 0.0 3.7 3 1 1 4 4 4 0 GAT domain Ank_2 PF12796.2 GAM29356.1 - 3.3e-06 27.3 0.1 0.085 13.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 GAM29356.1 - 0.00041 20.3 0.3 28 5.3 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 GAM29356.1 - 0.023 14.5 2.3 18 5.3 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat DUF3447 PF11929.3 GAM29356.1 - 0.12 12.1 0.1 0.12 12.1 0.0 2.7 3 2 0 3 3 3 0 Domain of unknown function (DUF3447) FNIP PF05725.7 GAM29357.1 - 1.4e-26 92.1 5.6 1.4e-10 40.9 0.1 5.9 4 2 0 5 5 5 4 FNIP Repeat Methyltransf_2 PF00891.13 GAM29358.1 - 5.8e-45 153.3 0.0 7.8e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase FeoC PF09012.5 GAM29358.1 - 0.0077 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 FeoC like transcriptional regulator Rrf2 PF02082.15 GAM29358.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation PF08100.6 GAM29358.1 - 0.12 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain Na_H_Exchanger PF00999.16 GAM29359.1 - 1.6e-57 194.7 41.0 2.6e-57 194.1 28.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BCHF PF07284.6 GAM29359.1 - 0.013 15.3 1.0 0.013 15.3 0.7 3.4 2 1 0 3 3 3 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DFP PF04127.10 GAM29360.1 - 2.2e-17 63.2 0.0 3.6e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RabGAP-TBC PF00566.13 GAM29361.1 - 2.3e-25 89.3 4.9 6.1e-17 61.8 0.3 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DEC-1_N PF04625.8 GAM29361.1 - 0.2 10.3 9.8 0.33 9.5 6.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Clathrin PF00637.15 GAM29363.1 - 7.2e-198 648.1 61.7 1.5e-31 108.8 0.7 9.1 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 GAM29363.1 - 7.2e-32 107.4 2.7 4e-06 26.7 0.0 7.9 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 GAM29363.1 - 2.5e-27 94.5 0.8 2.5e-27 94.5 0.5 2.5 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.5 GAM29363.1 - 9.4e-12 43.7 0.3 2.8e-11 42.1 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.1 GAM29363.1 - 0.0001 21.8 5.0 0.48 10.3 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 GAM29363.1 - 0.01 16.3 6.8 2.8e+02 2.5 0.0 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 GAM29363.1 - 0.19 11.6 20.3 1.4 8.9 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 GAM29363.1 - 0.75 9.5 19.7 0.29 10.8 0.1 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 GAM29363.1 - 2.3 8.2 13.3 1.1 9.2 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.2 GAM29364.1 - 1.5e-20 73.2 5.9 7e-05 23.0 0.0 6.5 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 GAM29364.1 - 5.1e-09 36.4 3.8 5.5 7.6 0.0 8.2 8 1 1 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.25 GAM29364.1 - 8.4e-09 34.8 2.4 3.2 7.7 0.0 8.7 9 0 0 9 9 9 2 Ankyrin repeat Ank_3 PF13606.1 GAM29364.1 - 4.2e-08 32.6 0.9 2.2 8.7 0.0 9.0 10 0 0 10 10 10 1 Ankyrin repeat Ank_5 PF13857.1 GAM29364.1 - 5.8e-08 32.7 9.1 0.035 14.3 0.3 6.9 6 2 2 8 8 8 2 Ankyrin repeats (many copies) EHN PF06441.7 GAM29366.1 - 0.14 12.1 0.2 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF4537 PF15057.1 GAM29367.1 - 0.00066 19.4 0.4 0.013 15.2 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) p53-inducible11 PF14936.1 GAM29368.1 - 1.2 9.0 5.1 1.4 8.7 3.5 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF2250 PF10007.4 GAM29372.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) FEZ PF07763.8 GAM29372.1 - 0.14 11.8 0.1 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 FEZ-like protein DUF4537 PF15057.1 GAM29373.1 - 0.012 15.3 1.6 0.043 13.5 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) SIN1 PF05422.7 GAM29375.1 - 0.1 11.1 1.3 0.13 10.7 0.9 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) RsgI_N PF12791.2 GAM29379.1 - 0.068 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Pox_A22 PF04848.8 GAM29385.1 - 0.03 14.1 0.0 0.05 13.4 0.0 1.3 1 1 0 1 1 1 0 Poxvirus A22 protein VirionAssem_T7 PF11653.3 GAM29386.1 - 0.26 12.0 9.7 1.5 9.5 2.5 2.1 1 1 1 2 2 2 0 Bacteriophage T7 virion assembly protein SseC PF04888.7 GAM29386.1 - 1.7 7.8 14.7 2.4 7.4 10.2 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Gemini_AL1 PF00799.15 GAM29387.1 - 0.0036 17.1 0.1 0.0087 15.8 0.1 1.6 1 1 1 2 2 2 1 Geminivirus Rep catalytic domain Bac_small_YrzI PF09501.5 GAM29387.1 - 0.043 13.7 1.2 0.062 13.2 0.1 2.0 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) DUF1638 PF07796.6 GAM29387.1 - 0.078 12.6 0.1 0.14 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) AgrB PF04647.10 GAM29389.1 - 0.045 12.8 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Accessory gene regulator B CD20 PF04103.10 GAM29389.1 - 0.054 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 CD20-like family Halogen_Hydrol PF10112.4 GAM29389.1 - 0.06 12.7 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pox_A32 PF04665.7 GAM29390.1 - 6.7e-08 32.1 0.4 9.6e-08 31.6 0.2 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein YqaJ PF09588.5 GAM29392.1 - 5e-26 91.5 0.0 1.9e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain Herpes_UL52 PF03121.10 GAM29392.1 - 0.015 14.9 0.4 0.036 13.8 0.2 1.6 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Mito_fiss_reg PF05308.6 GAM29392.1 - 3 7.1 6.9 7 5.9 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator dNK PF01712.14 GAM29393.1 - 6.3e-06 26.1 0.1 1.3e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Deoxynucleoside kinase OAS1_C PF10421.4 GAM29393.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus CRA PF06589.6 GAM29394.1 - 0.054 12.7 0.1 0.058 12.7 0.1 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF2457 PF10446.4 GAM29395.1 - 0.64 8.6 15.4 0.26 9.9 6.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 GAM29395.1 - 3.8 5.7 15.5 0.13 10.6 4.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) vMSA PF00695.14 GAM29396.1 - 0.15 11.2 0.9 0.2 10.8 0.6 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Gemini_AL2 PF01440.11 GAM29396.1 - 2.6 8.1 6.0 7.5 6.6 1.5 2.2 2 0 0 2 2 2 0 Geminivirus AL2 protein Capsid_NCLDV PF04451.7 GAM29398.1 - 0.0069 15.4 0.6 0.01 14.8 0.4 1.2 1 0 0 1 1 1 1 Large eukaryotic DNA virus major capsid protein EF-hand_2 PF09068.6 GAM29399.1 - 0.011 15.7 0.2 0.026 14.6 0.2 1.6 1 0 0 1 1 1 0 EF hand YedD PF13987.1 GAM29399.1 - 0.033 13.7 0.1 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 YedD-like protein SLT_2 PF13406.1 GAM29399.1 - 0.05 12.5 0.8 0.35 9.7 0.1 2.0 2 0 0 2 2 2 0 Transglycosylase SLT domain DUF524 PF04411.7 GAM29399.1 - 0.053 13.3 0.9 0.26 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF524) Wzt_C PF14524.1 GAM29401.1 - 0.085 12.5 0.1 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Wzt C-terminal domain Herpes_capsid PF06112.6 GAM29401.1 - 3 7.8 6.2 5.3 7.0 4.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Sporozoite_P67 PF05642.6 GAM29401.1 - 3.6 5.3 10.4 5.4 4.7 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tudor-knot PF11717.3 GAM29403.1 - 0.11 12.1 0.9 0.26 11.0 0.6 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Hamartin PF04388.7 GAM29403.1 - 0.84 8.2 6.7 1.4 7.5 4.6 1.3 1 0 0 1 1 1 0 Hamartin protein DDE_Tnp_4 PF13359.1 GAM29404.1 - 0.00023 20.8 0.2 0.00041 19.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Nop14 PF04147.7 GAM29404.1 - 0.017 13.1 16.7 0.021 12.7 11.6 1.0 1 0 0 1 1 1 0 Nop14-like family Ebola_NP PF05505.7 GAM29404.1 - 3.7 5.5 15.0 4.4 5.2 10.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein RVT_1 PF00078.22 GAM29406.1 - 7.4e-26 90.8 0.9 1.3e-25 90.0 0.7 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 GAM29406.1 - 4.9e-19 68.6 0.0 1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 GAM29406.1 - 0.03 13.7 0.1 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger UPF0181 PF03701.9 GAM29406.1 - 0.056 12.7 0.2 0.16 11.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) DUF1091 PF06477.8 GAM29408.1 - 0.082 13.3 0.4 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) Rubredoxin PF00301.15 GAM29408.1 - 0.1 12.5 1.4 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin Glutaredoxin PF00462.19 GAM29408.1 - 0.16 12.0 0.9 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Glutaredoxin Pro_isomerase PF00160.16 GAM29410.1 - 2.1e-46 157.9 0.3 2.1e-46 157.9 0.2 1.9 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MIP-T3 PF10243.4 GAM29410.1 - 0.067 11.6 27.0 0.081 11.3 18.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4551 PF15087.1 GAM29410.1 - 0.23 9.7 4.6 0.28 9.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FLO_LFY PF01698.11 GAM29410.1 - 0.34 9.7 17.0 0.56 8.9 11.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 GAM29410.1 - 0.94 8.8 20.3 2.7 7.3 14.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 GAM29410.1 - 1.4 8.0 15.4 2.8 7.0 10.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 GAM29410.1 - 2 5.9 11.1 2.5 5.6 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Bystin PF05291.6 GAM29411.1 - 1.1e-118 395.6 1.4 3.8e-118 393.8 0.0 2.0 2 0 0 2 2 2 1 Bystin XRN_N PF03159.13 GAM29412.1 - 5.4e-13 48.8 4.2 5.2e-10 39.1 0.0 2.7 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus DUF3439 PF11921.3 GAM29412.1 - 0.024 14.3 5.2 0.051 13.3 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GTP_EFTU PF00009.22 GAM29413.1 - 1.6e-37 128.8 2.3 1.6e-37 128.8 1.6 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 GAM29413.1 - 8.1e-16 57.8 1.1 1.4e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 GAM29413.1 - 2.6e-12 46.6 0.4 1.6e-06 28.0 0.8 3.4 3 1 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 GAM29413.1 - 2.5e-08 33.8 0.1 8.2e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 GAM29413.1 - 2e-07 31.5 0.1 2e-07 31.5 0.1 2.4 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 GAM29413.1 - 8.8e-05 21.8 0.2 0.00024 20.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 GAM29413.1 - 0.00015 21.2 0.6 0.00039 19.9 0.4 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 GAM29413.1 - 0.00051 19.3 0.1 0.00051 19.3 0.0 2.3 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 GAM29413.1 - 0.0012 18.4 4.2 0.006 16.2 2.2 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 ArgK PF03308.11 GAM29413.1 - 0.0089 14.8 0.8 0.0089 14.8 0.5 2.9 2 1 1 3 3 3 1 ArgK protein MobB PF03205.9 GAM29413.1 - 0.013 15.2 0.3 0.62 9.7 0.0 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 GAM29413.1 - 0.65 9.7 0.0 0.65 9.7 0.0 4.5 3 2 1 4 4 3 0 Dynamin family TFIIA PF03153.8 GAM29413.1 - 2.8 7.7 48.6 0.23 11.3 28.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 GAM29415.1 - 1.9e-46 158.3 4.3 1.7e-42 145.4 0.0 2.3 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29415.1 - 5.6e-35 120.6 0.0 3e-33 115.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 GAM29415.1 - 2.7e-06 26.5 1.1 2.7e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Med15 PF09606.5 GAM29415.1 - 1 7.4 13.3 1.2 7.2 9.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 GAM29416.1 - 1e-50 172.3 0.1 1.2e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29416.1 - 9.5e-36 123.1 0.0 1.2e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM29416.1 - 3.1e-09 36.1 0.0 5.5e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 GAM29416.1 - 0.022 13.8 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 GAM29416.1 - 0.052 12.3 0.4 0.09 11.5 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Malate_synthase PF01274.17 GAM29417.1 - 1.3e-208 693.3 0.0 1.5e-208 693.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Peptidase_C1_2 PF03051.10 GAM29417.1 - 0.055 11.9 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family Acetyltransf_1 PF00583.19 GAM29418.1 - 9.2e-14 51.2 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 GAM29418.1 - 2.8e-06 27.4 0.0 5.3e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 GAM29418.1 - 4e-05 23.7 0.0 6.3e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 GAM29418.1 - 7.9e-05 22.3 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 GAM29418.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cyt-b5 PF00173.23 GAM29419.1 - 4.2e-22 77.7 0.1 6.2e-22 77.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short PF00106.20 GAM29420.1 - 4.6e-06 26.6 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 GAM29420.1 - 0.0081 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 GAM29420.1 - 0.0081 15.0 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Epimerase PF01370.16 GAM29420.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBF_beta PF02312.12 GAM29422.1 - 0.0013 18.4 0.0 0.0015 18.2 0.0 1.0 1 0 0 1 1 1 1 Core binding factor beta subunit Acyl-CoA_dh_N PF02771.11 GAM29422.1 - 0.13 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain CENP-F_leu_zip PF10473.4 GAM29423.1 - 0.0015 18.4 10.1 0.0015 18.4 7.0 7.9 3 3 5 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LIM PF00412.17 GAM29424.1 - 6.7e-25 86.9 30.6 5.3e-09 36.0 4.4 3.6 3 0 0 3 3 3 3 LIM domain Rieske PF00355.21 GAM29424.1 - 0.052 13.1 10.9 0.46 10.0 0.8 3.5 3 0 0 3 3 3 0 Rieske [2Fe-2S] domain C1_1 PF00130.17 GAM29424.1 - 0.053 13.2 20.7 0.62 9.8 1.7 3.9 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3716 PF12511.3 GAM29424.1 - 0.18 11.4 18.9 0.74 9.4 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3716) Prok-RING_1 PF14446.1 GAM29424.1 - 0.3 10.8 22.8 0.85 9.4 1.4 3.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zip PF02535.17 GAM29424.1 - 1.1 8.1 8.6 2.1 7.2 5.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Mut7-C PF01927.11 GAM29424.1 - 8.4 6.3 17.4 5.5 6.9 1.8 3.5 3 0 0 3 3 3 0 Mut7-C RNAse domain LIM PF00412.17 GAM29425.1 - 1.5e-22 79.4 19.4 5.2e-13 48.8 6.0 2.6 2 0 0 2 2 2 2 LIM domain PH PF00169.24 GAM29425.1 - 1.1e-05 25.5 1.3 1.9e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 PH domain Citrate_synt PF00285.16 GAM29426.1 - 1.1e-126 422.3 0.0 1.5e-126 421.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Sod_Cu PF00080.15 GAM29427.1 - 3.5e-48 163.3 3.4 4e-48 163.1 2.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.20 GAM29429.1 - 9.8e-71 237.9 0.0 2.1e-70 236.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29429.1 - 6.4e-46 156.5 0.0 1e-45 155.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 GAM29429.1 - 7.5e-08 31.6 0.1 1.3e-06 27.6 0.0 2.4 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 GAM29429.1 - 0.0018 18.0 0.0 0.027 14.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 GAM29429.1 - 0.03 13.3 0.0 0.084 11.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 GAM29429.1 - 0.046 12.5 0.0 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 DUF972 PF06156.8 GAM29429.1 - 0.26 11.6 1.8 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) V-SNARE PF05008.10 GAM29430.1 - 2.7e-06 27.4 4.9 3.8e-06 26.9 1.4 2.4 1 1 1 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Pox_A14 PF05767.7 GAM29430.1 - 0.016 15.1 0.1 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 BLOC1_2 PF10046.4 GAM29430.1 - 0.078 13.1 2.9 0.17 12.0 2.0 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MSC PF09402.5 GAM29430.1 - 0.32 9.6 3.3 0.8 8.3 0.0 2.4 1 1 2 3 3 3 0 Man1-Src1p-C-terminal domain zf-C4H2 PF10146.4 GAM29430.1 - 0.74 9.7 4.5 0.91 9.4 2.8 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein Peptidase_M28 PF04389.12 GAM29433.1 - 5.9e-21 75.0 0.1 1.2e-20 74.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 GAM29433.1 - 6.4e-09 35.4 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 GAM29433.1 - 0.025 13.8 0.1 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Nicastrin DUF2362 PF10154.4 GAM29434.1 - 8.2e-06 24.7 17.3 0.00044 19.0 8.3 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2362) CsoSCA PF08936.5 GAM29434.1 - 0.065 11.5 0.6 0.096 11.0 0.4 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DUF364 PF04016.7 GAM29434.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Topoisom_I_N PF02919.10 GAM29434.1 - 1.1 8.5 7.2 1.2 8.4 4.3 1.5 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment NDUF_B8 PF05821.6 GAM29436.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) MRP-L47 PF06984.8 GAM29437.1 - 2.1e-21 75.6 0.2 5.2e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 GAM29437.1 - 0.0002 20.9 1.3 0.00061 19.4 0.9 1.9 1 1 0 1 1 1 1 Ribosomal L29 protein Ubiq-Cytc-red_N PF09165.5 GAM29437.1 - 0.014 15.7 0.5 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal PBD PF00786.23 GAM29438.1 - 9.7e-06 25.9 0.0 9.7e-06 25.9 0.0 6.0 6 0 0 6 6 6 1 P21-Rho-binding domain Tropomyosin PF00261.15 GAM29438.1 - 0.0024 17.0 12.1 0.0024 17.0 8.4 6.8 2 2 4 6 6 6 2 Tropomyosin ELK PF03789.8 GAM29438.1 - 0.0044 16.7 1.7 5.4 6.9 0.1 4.7 4 0 0 4 4 4 1 ELK domain ODR4-like PF14778.1 GAM29439.1 - 3.4e-57 193.7 2.1 6.2e-57 192.9 1.5 1.4 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF912 PF06024.7 GAM29439.1 - 0.0046 16.9 3.9 0.29 11.1 0.0 2.6 2 0 0 2 2 2 2 Nucleopolyhedrovirus protein of unknown function (DUF912) Hep_59 PF07052.6 GAM29439.1 - 0.012 15.9 2.9 0.012 15.9 2.0 2.8 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 Pex14_N PF04695.8 GAM29439.1 - 0.052 13.5 8.9 0.59 10.1 0.5 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4448 PF14610.1 GAM29439.1 - 0.097 12.1 1.5 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 GAM29439.1 - 3.8 7.1 12.1 0.24 11.0 0.3 2.7 3 0 0 3 3 3 0 TMEM154 protein family Suf PF05843.9 GAM29439.1 - 4.6 6.8 14.5 1.6 8.4 3.6 2.7 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) UCR_6-4kD PF08997.5 GAM29440.1 - 1.4e-06 27.8 0.0 1.7e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.4 GAM29440.1 - 0.0002 20.9 3.7 0.00093 18.8 2.6 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RRM_2 PF04059.7 GAM29441.1 - 1.4e-29 101.8 0.5 2.8e-29 100.9 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 GAM29441.1 - 0.00041 19.9 0.0 0.00084 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 GAM29441.1 - 0.028 14.4 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ERbeta_N PF12497.3 GAM29442.1 - 0.086 12.6 0.6 0.084 12.7 0.4 1.2 1 0 0 1 1 1 0 Estrogen receptor beta Coiled-coil_56 PF09813.4 GAM29442.1 - 0.18 11.8 1.4 0.41 10.6 0.7 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 RFXA_RFXANK_bdg PF15289.1 GAM29442.1 - 0.2 11.8 6.8 0.28 11.3 4.7 1.3 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain TAT_ubiq PF07706.7 GAM29442.1 - 0.24 11.3 1.5 0.55 10.2 1.0 1.7 1 1 0 1 1 1 0 Aminotransferase ubiquitination site BAF1_ABF1 PF04684.8 GAM29442.1 - 1.1 8.0 7.4 1.2 7.8 5.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FNIP PF05725.7 GAM29443.1 - 1.9e-29 101.3 16.3 6.4e-10 38.8 1.6 4.8 5 0 0 5 5 5 4 FNIP Repeat FNIP PF05725.7 GAM29444.1 - 8.5e-82 268.8 17.4 5.6e-11 42.2 0.1 7.7 1 1 8 10 10 10 10 FNIP Repeat ParBc_2 PF08857.6 GAM29444.1 - 0.15 11.8 2.1 1e+02 2.6 0.0 5.4 3 3 2 6 6 6 0 Putative ParB-like nuclease Glyco_hydro_4C PF11975.3 GAM29444.1 - 8 6.1 7.6 2.6e+02 1.2 0.0 6.1 6 2 3 9 9 9 0 Family 4 glycosyl hydrolase C-terminal domain DUF3830 PF12903.2 GAM29445.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) DnaJ PF00226.26 GAM29447.1 - 3.9e-07 29.6 0.1 1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain CDC45 PF02724.9 GAM29447.1 - 0.024 12.7 8.6 0.029 12.4 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 GAM29447.1 - 0.035 13.3 7.0 0.045 13.0 4.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Serinc PF03348.10 GAM29447.1 - 0.073 11.7 1.0 0.096 11.3 0.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 GAM29447.1 - 0.18 11.6 1.4 0.21 11.4 1.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CENP-B_dimeris PF09026.5 GAM29447.1 - 0.22 11.7 13.6 0.09 13.0 6.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FPN1 PF06963.7 GAM29447.1 - 0.23 9.7 0.4 0.32 9.3 0.3 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Spc7_N PF15402.1 GAM29447.1 - 0.26 9.2 15.5 0.33 8.9 10.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Gag_spuma PF03276.9 GAM29447.1 - 0.28 9.4 14.0 0.39 8.9 9.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Pox_Ag35 PF03286.9 GAM29447.1 - 0.32 10.4 8.1 0.51 9.8 5.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2215 PF10225.4 GAM29447.1 - 0.42 10.0 2.1 0.63 9.4 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1510 PF07423.6 GAM29447.1 - 0.46 9.8 11.9 0.66 9.3 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ndc1_Nup PF09531.5 GAM29447.1 - 0.51 8.7 7.2 0.62 8.4 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Na_trans_assoc PF06512.8 GAM29447.1 - 0.58 10.0 10.8 2.4 8.0 5.5 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated MSA-2c PF12238.3 GAM29447.1 - 0.99 9.0 9.5 1.5 8.4 5.7 2.0 1 1 0 1 1 1 0 Merozoite surface antigen 2c DUF775 PF05603.7 GAM29447.1 - 1 8.8 9.1 0.11 11.9 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF3735 PF12537.3 GAM29447.1 - 1 9.4 3.5 9.1 6.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3735) PPP4R2 PF09184.6 GAM29447.1 - 1.2 8.6 18.5 2.1 7.8 12.8 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.7 GAM29447.1 - 1.5 8.5 19.3 2.5 7.7 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.2 GAM29447.1 - 1.7 6.2 11.9 1.8 6.1 7.8 1.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein NOA36 PF06524.7 GAM29447.1 - 6.5 5.9 14.0 8.8 5.4 9.7 1.2 1 0 0 1 1 1 0 NOA36 protein DivIC PF04977.10 GAM29447.1 - 9 5.8 13.6 22 4.6 9.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Glyco_hydro_18 PF00704.23 GAM29448.1 - 1.2e-21 77.5 3.2 2e-21 76.8 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Voltage_CLC PF00654.15 GAM29449.1 - 6.2e-95 318.2 27.4 6.5e-95 318.1 16.7 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 GAM29449.1 - 3.4e-14 52.3 0.2 9.6e-06 25.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain UCR_Fe-S_N PF10399.4 GAM29449.1 - 0.0052 15.9 1.1 0.017 14.2 0.7 1.9 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 GAM29449.1 - 0.0059 16.5 1.7 0.0059 16.5 1.2 3.0 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence DUF2418 PF10332.4 GAM29449.1 - 0.42 10.9 0.1 0.42 10.9 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2418) LIM PF00412.17 GAM29450.1 - 2.1e-11 43.7 5.8 3.2e-11 43.1 4.0 1.3 1 0 0 1 1 1 1 LIM domain Gaa1 PF04114.9 GAM29451.1 - 3e-26 92.2 21.3 6e-25 87.9 14.8 2.6 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component CDC45 PF02724.9 GAM29451.1 - 0.074 11.0 1.2 0.1 10.6 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 GAM29452.1 - 9.1e-47 157.3 5.9 1.3e-12 47.8 0.0 6.0 3 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 GAM29452.1 - 3.3e-40 133.9 8.8 0.00016 21.3 0.0 9.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 GAM29452.1 - 1.2e-38 130.7 4.5 1.2e-05 25.7 0.0 8.0 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 GAM29452.1 - 2.9e-31 106.7 5.6 3e-06 27.2 0.0 7.9 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 GAM29452.1 - 7.6e-20 69.0 7.2 0.0046 17.0 0.0 9.0 8 1 0 8 8 8 5 Ankyrin repeat BTB PF00651.26 GAM29452.1 - 1.4e-17 63.6 0.2 0.00038 20.4 0.0 4.9 5 0 0 5 5 5 4 BTB/POZ domain zf-ribbon_3 PF13248.1 GAM29453.1 - 0.033 13.3 1.9 4.5 6.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 GAM29453.1 - 0.4 10.2 2.1 7.3 6.2 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 GAM29453.1 - 0.43 10.1 2.9 15 5.1 0.0 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DB PF01682.14 GAM29454.1 - 3.1 7.8 6.2 1.1 9.3 0.7 2.1 2 0 0 2 2 2 0 DB module PBD PF00786.23 GAM29456.1 - 2.8e-06 27.6 0.0 2.8e-06 27.6 0.0 4.0 3 1 0 3 3 3 1 P21-Rho-binding domain MRP-L47 PF06984.8 GAM29457.1 - 2.1e-21 75.6 0.2 5e-21 74.3 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 GAM29457.1 - 0.00019 21.0 1.3 0.0006 19.4 0.9 1.9 1 1 0 1 1 1 1 Ribosomal L29 protein Ubiq-Cytc-red_N PF09165.5 GAM29457.1 - 0.013 15.7 0.5 4 7.8 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal DUF2362 PF10154.4 GAM29460.1 - 1.5e-79 268.0 2.0 5.9e-44 150.6 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2362) Imm14 PF15428.1 GAM29460.1 - 0.12 12.7 0.1 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 14 SK_channel PF03530.9 GAM29465.1 - 0.15 11.9 6.0 0.035 13.9 1.1 2.2 2 1 0 2 2 2 0 Calcium-activated SK potassium channel IF-2B PF01008.12 GAM29466.1 - 5.1e-72 242.2 0.0 5.9e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LRR_4 PF12799.2 GAM29467.1 - 0.00037 20.0 12.8 0.13 11.9 0.2 5.6 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 GAM29467.1 - 0.25 11.1 10.6 18 5.1 0.3 4.9 4 1 2 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 GAM29467.1 - 4.3 7.7 13.5 56 4.3 0.1 5.7 5 1 1 6 6 6 0 Leucine Rich Repeat TMEM154 PF15102.1 GAM29467.1 - 7.5 6.2 13.5 3.1 7.4 7.3 1.9 2 0 0 2 2 2 0 TMEM154 protein family LRR_7 PF13504.1 GAM29468.1 - 0.0014 18.4 7.1 1.8 9.0 0.0 6.4 7 0 0 7 7 7 1 Leucine rich repeat LRR_4 PF12799.2 GAM29468.1 - 0.004 16.7 0.0 0.004 16.7 0.0 4.7 5 2 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 GAM29468.1 - 0.0042 16.9 1.8 2.7 8.3 0.0 5.2 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 GAM29468.1 - 0.007 16.3 9.1 0.096 12.8 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.1 GAM29468.1 - 0.16 11.7 16.9 0.84 9.4 0.1 5.3 3 2 1 4 4 4 0 Leucine rich repeat HATPase_c PF02518.21 GAM29470.1 - 1.1e-28 99.2 0.2 2.6e-28 97.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 GAM29470.1 - 2.3e-24 85.5 0.1 4.9e-23 81.2 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 GAM29470.1 - 1.4e-15 57.0 0.1 1.4e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 GAM29470.1 - 9.3e-05 22.1 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.1 GAM29470.1 - 0.0061 16.2 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Histone PF00125.19 GAM29471.1 - 4.1e-09 36.4 0.1 5.4e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DnaJ PF00226.26 GAM29472.1 - 3.7e-07 29.7 0.1 8.8e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain PCEMA1 PF07418.6 GAM29472.1 - 0.029 13.7 8.3 0.039 13.3 5.8 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Plasmid_stab_B PF10784.4 GAM29472.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein Lin-8 PF03353.10 GAM29472.1 - 0.041 13.1 3.8 0.044 13.0 2.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SGT1 PF07093.6 GAM29472.1 - 0.047 12.0 10.4 0.063 11.6 7.2 1.1 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.9 GAM29472.1 - 0.082 10.9 6.3 0.099 10.6 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 GAM29472.1 - 0.71 9.3 12.9 1.2 8.6 8.9 1.3 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.7 GAM29472.1 - 1.1 8.9 11.8 1.8 8.2 8.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DivIC PF04977.10 GAM29472.1 - 4.6 6.8 8.6 10 5.6 6.0 1.6 1 0 0 1 1 1 0 Septum formation initiator PHD_3 PF13922.1 GAM29472.1 - 5.8 7.2 6.8 14 6.0 4.7 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx NOA36 PF06524.7 GAM29472.1 - 7.7 5.6 10.8 11 5.1 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein SAM_2 PF07647.12 GAM29473.1 - 0.00035 20.3 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 GAM29473.1 - 0.0012 18.9 0.1 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HSDR_N PF04313.9 GAM29473.1 - 0.005 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N_2 PF13588.1 GAM29473.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Nop14 PF04147.7 GAM29474.1 - 0.024 12.5 10.2 0.03 12.2 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 GAM29474.1 - 0.029 12.4 5.5 0.037 12.0 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 GAM29474.1 - 0.049 11.4 4.1 0.063 11.1 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 GAM29474.1 - 0.077 12.2 8.9 0.11 11.8 6.2 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 GAM29474.1 - 0.65 8.4 12.9 0.87 7.9 8.9 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 GAM29474.1 - 1.2 8.8 5.6 2 8.0 3.9 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 GAM29474.1 - 1.2 9.4 17.1 2.5 8.4 11.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 GAM29474.1 - 1.3 7.6 26.4 1.9 7.1 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 GAM29474.1 - 1.5 8.7 16.7 2.3 8.1 11.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.6 GAM29474.1 - 1.6 6.7 6.8 2 6.4 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 GAM29474.1 - 2 7.7 11.6 0.065 12.5 4.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sigma70_ner PF04546.8 GAM29474.1 - 7.8 6.0 15.6 13 5.2 10.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2722 PF10846.3 GAM29474.1 - 9.2 5.1 8.6 13 4.6 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RVT_1 PF00078.22 GAM29475.1 - 3.6e-06 26.4 0.1 9.5e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 GAM29476.1 - 0.014 14.9 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase WH2 PF02205.15 GAM29478.1 - 0.0005 19.5 1.5 0.0005 19.5 1.0 2.1 2 0 0 2 2 2 1 WH2 motif Pkinase PF00069.20 GAM29478.1 - 0.00057 19.1 0.3 0.0021 17.2 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29478.1 - 0.00071 18.7 0.0 0.0021 17.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase ABC2_membrane_3 PF12698.2 GAM29478.1 - 0.031 13.3 3.3 0.066 12.2 1.0 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF605 PF04652.11 GAM29478.1 - 3.4 6.9 18.7 4.6 6.5 13.0 1.2 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 GAM29478.1 - 6.9 4.3 6.3 9.6 3.8 4.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein Gag_spuma PF03276.9 GAM29478.1 - 8.3 4.5 18.2 12 4.0 12.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Ctr PF04145.10 GAM29479.1 - 3.4e-29 101.7 2.1 6e-29 100.9 1.5 1.4 1 0 0 1 1 1 1 Ctr copper transporter family DDE_Tnp_4 PF13359.1 GAM29480.1 - 1.8e-25 89.3 0.0 2.1e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 GAM29480.1 - 9.5e-11 41.6 0.2 2.9e-10 40.0 0.2 1.6 1 1 0 1 1 1 1 Transposase DDE domain Pex14_N PF04695.8 GAM29481.1 - 0.12 12.3 2.7 0.13 12.3 1.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FNIP PF05725.7 GAM29483.1 - 6e-11 42.1 1.7 0.0051 16.7 0.0 5.1 4 2 0 4 4 4 3 FNIP Repeat LRR_5 PF13306.1 GAM29483.1 - 0.045 13.4 0.2 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) WHIM1 PF15612.1 GAM29484.1 - 0.19 11.7 2.6 0.66 10.0 0.1 2.6 2 1 1 3 3 3 0 WSTF, HB1, Itc1p, MBD9 motif 1 EST1 PF10374.4 GAM29485.1 - 0.078 12.9 1.5 0.19 11.6 1.0 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 Peptidase_C48 PF02902.14 GAM29486.1 - 0.00062 19.4 1.5 0.001 18.7 0.3 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Nop53 PF07767.6 GAM29487.1 - 0.0014 17.7 6.4 0.0016 17.5 4.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Prothymosin PF03247.9 GAM29487.1 - 0.099 12.7 14.2 0.12 12.4 9.9 1.3 1 1 0 1 1 1 0 Prothymosin/parathymosin family Vfa1 PF08432.5 GAM29487.1 - 0.51 10.3 7.9 0.52 10.3 5.4 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_RNA_Pol_19 PF05320.7 GAM29487.1 - 0.95 9.1 5.2 1.1 8.9 3.6 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nucleoplasmin PF03066.10 GAM29487.1 - 3 7.3 8.4 3.5 7.1 5.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 GAM29487.1 - 3.3 5.6 8.2 3.1 5.7 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 GAM29487.1 - 4.4 6.3 11.3 5.1 6.1 7.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 GAM29487.1 - 5.2 6.2 7.3 5.3 6.2 5.1 1.1 1 0 0 1 1 1 0 NOA36 protein Exo_endo_phos_2 PF14529.1 GAM29488.1 - 4.3e-05 23.0 0.7 5.2e-05 22.8 0.5 1.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase HIM1 PF08732.5 GAM29488.1 - 0.072 11.5 0.5 0.092 11.1 0.3 1.1 1 0 0 1 1 1 0 HIM1 GUCT PF08152.7 GAM29490.1 - 0.023 14.6 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 GUCT (NUC152) domain Death PF00531.17 GAM29490.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Death domain Aminotran_1_2 PF00155.16 GAM29490.1 - 0.11 11.4 0.0 0.32 9.9 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class I and II DUF717 PF05338.7 GAM29491.1 - 0.0018 18.1 1.3 1.2 9.0 0.0 3.8 2 1 0 2 2 2 1 Protein of unknown function (DUF717) FlaC_arch PF05377.6 GAM29491.1 - 0.017 15.0 1.2 0.65 9.9 0.3 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 GAM29491.1 - 0.92 9.3 5.6 2.7 7.7 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMP_2 PF06791.8 GAM29491.1 - 2 7.9 6.1 2.6 7.5 0.4 2.4 2 0 0 2 2 2 0 Prophage tail length tape measure protein Tropomyosin PF00261.15 GAM29491.1 - 2.6 7.0 7.0 0.51 9.3 2.1 1.8 2 0 0 2 2 2 0 Tropomyosin Matrilin_ccoil PF10393.4 GAM29491.1 - 3.7 6.9 6.6 0.6 9.5 0.4 2.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Laminin_II PF06009.7 GAM29491.1 - 5.8 6.6 11.5 0.53 10.0 1.0 3.1 3 0 0 3 3 3 0 Laminin Domain II Fzo_mitofusin PF04799.8 GAM29491.1 - 6.5 6.1 14.3 5.1 6.4 0.2 3.4 3 0 0 3 3 3 0 fzo-like conserved region AAA PF00004.24 GAM29492.1 - 7.4e-44 149.1 0.0 1.9e-43 147.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 GAM29492.1 - 1.4e-08 34.8 0.1 1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 GAM29492.1 - 1.6e-06 27.9 0.0 5.9e-06 26.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 GAM29492.1 - 6.2e-06 26.3 0.1 9.5e-05 22.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 GAM29492.1 - 9.9e-06 25.7 0.5 0.00041 20.4 0.2 2.8 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 GAM29492.1 - 7.2e-05 23.6 0.3 0.00027 21.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 GAM29492.1 - 7.4e-05 22.4 0.3 0.00033 20.3 0.0 2.1 2 1 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 GAM29492.1 - 0.00012 21.1 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 GAM29492.1 - 0.00043 19.7 0.0 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 GAM29492.1 - 0.00096 17.9 0.0 0.0021 16.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 GAM29492.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 GAM29492.1 - 0.0016 18.7 0.6 0.026 14.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 GAM29492.1 - 0.0025 17.6 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 GAM29492.1 - 0.0038 16.8 0.0 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 GAM29492.1 - 0.0042 16.2 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 GAM29492.1 - 0.0049 16.8 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 GAM29492.1 - 0.005 16.1 0.0 0.079 12.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 GAM29492.1 - 0.0062 15.6 0.0 0.02 14.0 0.0 1.8 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 GAM29492.1 - 0.0071 15.5 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 GAM29492.1 - 0.0075 15.6 0.1 0.087 12.2 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 GAM29492.1 - 0.012 15.1 0.1 0.034 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 GAM29492.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 GAM29492.1 - 0.02 14.4 0.1 0.091 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 GAM29492.1 - 0.025 13.4 0.0 0.06 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 GAM29492.1 - 0.028 14.4 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 GAM29492.1 - 0.032 13.7 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 GAM29492.1 - 0.035 14.4 0.2 0.58 10.4 0.0 2.5 3 1 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.12 GAM29492.1 - 0.038 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PAS_11 PF14598.1 GAM29492.1 - 0.071 13.0 0.1 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain DUF2075 PF09848.4 GAM29492.1 - 0.089 11.7 0.4 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 GAM29492.1 - 0.1 12.2 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain IncA PF04156.9 GAM29492.1 - 0.14 11.7 2.5 0.3 10.6 1.7 1.5 1 0 0 1 1 1 0 IncA protein AAA_13 PF13166.1 GAM29492.1 - 0.15 10.5 2.2 4.6 5.5 1.4 2.6 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 GAM29492.1 - 0.42 10.9 3.9 18 5.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1090 PF06476.7 GAM29492.1 - 0.5 10.0 5.0 10 5.8 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) FlaC_arch PF05377.6 GAM29492.1 - 1.3 8.9 8.3 2.1 8.3 3.9 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad2 PF08654.5 GAM29492.1 - 1.5 8.8 6.0 0.39 10.7 1.6 1.9 2 0 0 2 2 1 0 DASH complex subunit Dad2 RVT_1 PF00078.22 GAM29493.1 - 3.6e-10 39.5 0.4 1.4e-09 37.6 0.3 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Histone PF00125.19 GAM29497.1 - 2.7e-23 81.8 0.9 4e-23 81.3 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 GAM29497.1 - 1.5e-05 25.0 0.3 2.5e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 GAM29497.1 - 0.00018 20.9 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 GAM29497.1 - 0.018 15.0 0.7 0.03 14.3 0.5 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3458 PF11940.3 GAM29497.1 - 0.048 12.4 0.2 0.066 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Bromo_TP PF07524.8 GAM29497.1 - 0.094 12.4 0.2 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Ste50p-SAM PF09235.5 GAM29498.1 - 0.011 15.6 0.1 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_1 PF00536.25 GAM29498.1 - 0.015 15.4 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) rRNA_proc-arch PF13234.1 GAM29498.1 - 0.022 13.9 0.3 0.035 13.2 0.2 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain Dimer_Tnp_hAT PF05699.9 GAM29499.1 - 1.4e-07 31.0 0.5 7e-07 28.7 0.1 2.5 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 GAM29499.1 - 0.0007 19.5 1.4 0.0034 17.3 1.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) rve PF00665.21 GAM29500.1 - 2.4e-15 56.6 0.0 9.4e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 GAM29500.1 - 9.3e-07 28.1 0.2 2.4e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 GAM29500.1 - 1.5e-05 24.4 1.5 0.0001 21.7 0.1 2.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 GAM29503.1 - 1.9e-09 37.4 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4413 PF14372.1 GAM29504.1 - 0.0006 19.7 0.2 0.0014 18.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) ComFB PF10719.4 GAM29504.1 - 0.0023 17.6 0.2 0.0058 16.3 0.1 1.6 1 0 0 1 1 1 1 Late competence development protein ComFB DUF4608 PF15381.1 GAM29505.1 - 0.083 13.0 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) zf-BED PF02892.10 GAM29505.1 - 0.13 12.0 2.1 0.29 10.9 1.5 1.6 1 0 0 1 1 1 0 BED zinc finger Pkinase PF00069.20 GAM29506.1 - 7.1e-44 149.8 0.1 1.5e-16 60.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 GAM29506.1 - 2e-24 86.0 0.0 2e-09 36.9 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 GAM29506.1 - 0.08 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Auxin_canalis PF05703.6 GAM29506.1 - 0.5 10.1 2.3 0.37 10.5 0.1 1.8 3 0 0 3 3 3 0 Auxin canalisation Peptidase_C48 PF02902.14 GAM29507.1 - 0.00045 19.8 0.4 0.00045 19.8 0.3 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S49_N PF08496.5 GAM29507.1 - 0.033 14.0 3.9 0.053 13.3 2.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal He_PIG PF05345.7 GAM29507.1 - 0.14 12.2 0.3 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Putative Ig domain DUF4604 PF15377.1 GAM29511.1 - 2.6e-07 30.9 29.2 3.3e-06 27.4 20.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4604)