# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- zf-RING_2 PF13639.1 EPR77653.1 - 6e-14 51.6 7.6 2.9e-13 49.3 4.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPR77653.1 - 8.2e-08 31.8 4.1 1.5e-07 30.9 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPR77653.1 - 1.1e-07 31.6 7.1 1.1e-07 31.6 4.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPR77653.1 - 2.6e-06 27.4 6.5 1.2e-05 25.3 4.2 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPR77653.1 - 3.8e-06 26.4 5.0 3.8e-06 26.4 3.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR77653.1 - 0.00018 21.1 3.0 0.00031 20.3 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EPR77653.1 - 0.0026 17.4 3.9 0.055 13.1 2.0 2.4 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EPR77653.1 - 0.003 17.2 3.1 0.056 13.1 0.1 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 RINGv PF12906.2 EPR77653.1 - 0.0067 16.4 5.0 0.033 14.2 2.6 2.2 2 0 0 2 2 2 1 RING-variant domain zf-Apc11 PF12861.2 EPR77653.1 - 0.011 15.6 3.8 0.025 14.4 2.6 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EPR77653.1 - 0.29 11.1 9.9 5.8 6.9 6.0 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EPR77653.1 - 0.3 10.7 4.0 0.64 9.6 2.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EPR77653.1 - 1.7 8.7 6.2 7.7 6.6 3.0 2.3 2 0 0 2 2 2 0 RING-like domain zf-RING_UBOX PF13445.1 EPR77653.1 - 3 7.6 6.6 2.4 7.9 2.8 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-P11 PF03854.9 EPR77653.1 - 3.2 7.2 8.8 2.8 7.4 4.5 1.9 2 0 0 2 2 2 0 P-11 zinc finger FixP_N PF14715.1 EPR77654.1 - 0.047 13.0 3.3 1.5 8.2 0.1 3.0 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Homeobox PF00046.24 EPR77655.1 - 2.3e-14 52.7 1.0 4.2e-14 51.8 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPR77655.1 - 3.4e-08 33.0 0.6 6.5e-08 32.1 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain MRG PF05712.8 EPR77655.1 - 0.013 14.4 0.1 0.025 13.4 0.0 1.4 1 1 0 1 1 1 0 MRG Homez PF11569.3 EPR77655.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Borrelia_lipo_2 PF06238.6 EPR77655.1 - 0.3 11.1 2.3 0.38 10.8 0.6 2.1 1 1 1 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein DUF2313 PF10076.4 EPR77656.1 - 0.0098 15.3 0.1 0.01 15.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2313) CTNNBL PF08216.6 EPR77656.1 - 0.39 10.3 5.9 1 8.9 3.7 2.0 1 1 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear LRR_8 PF13855.1 EPR77658.1 - 3.3e-12 45.9 18.7 2.7e-08 33.4 5.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EPR77658.1 - 5.2e-09 35.5 8.0 0.00021 20.8 2.2 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77658.1 - 6.4e-09 34.6 9.0 0.041 13.8 0.0 4.5 4 0 0 4 4 4 4 Leucine Rich Repeat LRR_6 PF13516.1 EPR77658.1 - 0.0013 18.5 3.9 0.031 14.3 0.2 3.4 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 EPR77658.1 - 0.0019 18.1 3.7 5.5 7.6 0.0 4.2 4 0 0 4 4 4 2 Leucine rich repeat LRR_8 PF13855.1 EPR77659.1 - 4.5e-10 39.1 29.0 1.4e-05 24.7 5.0 4.4 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EPR77659.1 - 1e-09 37.7 37.1 9.7e-08 31.4 3.3 5.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77659.1 - 3.1e-07 29.4 27.4 0.18 11.9 1.2 7.2 7 1 0 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR77659.1 - 0.00013 21.5 20.7 1.8 9.0 0.1 7.1 6 2 0 6 6 6 4 Leucine rich repeat LRR_6 PF13516.1 EPR77659.1 - 0.36 11.0 35.1 1.6 9.0 0.3 7.2 6 3 1 7 7 7 0 Leucine Rich repeat LNS2 PF08235.8 EPR77660.1 - 2.4e-62 209.1 0.0 5.5e-62 207.9 0.0 1.6 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EPR77660.1 - 3.9e-29 100.5 0.9 3.9e-29 100.5 0.6 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Sigma54_activ_2 PF14532.1 EPR77660.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MAGP PF05507.6 EPR77661.1 - 0.022 14.5 4.6 0.037 13.8 0.0 2.3 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Zip PF02535.17 EPR77661.1 - 1.1 8.2 2.6 1.4 7.8 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 EPR77661.1 - 1.2 9.0 26.7 0.7 9.7 17.5 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 EPR77661.1 - 2 7.4 8.5 2.8 7.0 5.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ran_BP1 PF00638.13 EPR77663.1 - 2.1e-22 79.4 3.3 2.1e-22 79.4 2.3 1.7 2 0 0 2 2 2 1 RanBP1 domain Atg14 PF10186.4 EPR77663.1 - 0.092 11.6 10.4 0.12 11.2 7.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Hid1 PF12722.2 EPR77663.1 - 1.8 6.1 12.6 2.2 5.8 8.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EPR77663.1 - 3.2 5.6 19.2 4.2 5.2 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 EPR77663.1 - 8.3 4.5 5.6 11 4.2 3.9 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF2922 PF11148.3 EPR77664.1 - 0.55 9.9 8.7 0.34 10.6 1.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) Septin PF00735.13 EPR77665.1 - 2.7e-49 167.6 5.7 2.7e-49 167.6 3.9 2.4 1 1 1 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPR77665.1 - 0.0089 15.9 0.3 0.043 13.7 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase CHD5 PF04420.9 EPR77665.1 - 0.032 13.8 2.7 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 CHD5-like protein AIG1 PF04548.11 EPR77665.1 - 0.14 11.2 6.4 0.52 9.3 0.3 2.7 2 1 0 2 2 2 0 AIG1 family PfkB PF00294.19 EPR77666.1 - 1.2e-16 60.7 0.0 1.9e-16 60.0 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase LRR_4 PF12799.2 EPR77668.1 - 8.2e-11 41.2 16.3 2.7e-07 30.0 5.2 3.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77668.1 - 2e-10 40.2 16.8 1.5e-07 31.0 4.0 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR77668.1 - 2.2e-05 23.8 22.0 0.017 15.0 0.8 5.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR77668.1 - 0.00034 20.3 7.5 0.14 12.4 0.1 4.9 4 0 0 4 4 4 1 Leucine rich repeat Cas6 PF09559.5 EPR77668.1 - 0.089 12.5 0.7 2.2 7.9 0.0 2.0 1 1 1 2 2 2 0 Cas6 Crispr LRR_9 PF14580.1 EPR77668.1 - 0.5 9.9 5.3 1.7 8.1 0.8 2.3 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.1 EPR77668.1 - 3 8.2 15.5 7.1 7.0 0.4 4.6 3 1 1 4 4 4 0 Leucine Rich repeat CIAPIN1 PF05093.8 EPR77672.1 - 2.2e-20 72.6 15.8 2.6e-18 65.9 2.8 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Plasmodium_Vir PF05795.6 EPR77673.1 - 2e-05 23.9 10.9 2.4e-05 23.7 7.6 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Herpes_gE PF02480.11 EPR77673.1 - 0.0014 16.9 0.0 0.0019 16.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2370 PF10176.4 EPR77673.1 - 0.0041 16.5 2.0 0.0072 15.6 1.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) Zip PF02535.17 EPR77673.1 - 0.025 13.5 0.3 0.049 12.6 0.0 1.5 1 1 1 2 2 2 0 ZIP Zinc transporter FAM176 PF14851.1 EPR77673.1 - 0.03 14.0 0.0 0.03 14.0 0.0 2.6 1 1 2 3 3 3 0 FAM176 family DUF3899 PF13038.1 EPR77673.1 - 0.045 13.9 3.5 0.1 12.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF4027 PF13219.1 EPR77673.1 - 0.078 12.4 0.5 0.13 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DUF2207 PF09972.4 EPR77673.1 - 0.081 11.4 4.0 0.14 10.7 2.5 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 EPR77673.1 - 0.086 12.5 0.4 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Fic_N PF13784.1 EPR77673.1 - 0.1 12.4 0.5 0.2 11.5 0.4 1.5 1 0 0 1 1 1 0 Fic/DOC family N-terminal DUF367 PF04034.8 EPR77673.1 - 1.2 8.7 4.8 9.9 5.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF367) DUF912 PF06024.7 EPR77673.1 - 1.7 8.7 8.4 0.79 9.8 0.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med3 PF11593.3 EPR77673.1 - 3.4 6.8 13.6 4.8 6.3 9.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal V-ATPase_G PF03179.10 EPR77674.1 - 0.84 9.9 4.5 1.9 8.8 3.1 1.7 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit zf-SAP30 PF13866.1 EPR77674.1 - 2.3 7.9 6.4 0.39 10.4 1.6 1.8 2 0 0 2 2 2 0 SAP30 zinc-finger MIF4G_like_2 PF09090.6 EPR77675.1 - 0.061 12.5 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 MIF4G like tRNA-synt_His PF13393.1 EPR77677.1 - 1.7e-36 125.8 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EPR77677.1 - 1.3e-14 54.1 0.0 5.5e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPR77677.1 - 1.1e-08 34.8 2.2 3.1e-08 33.4 1.5 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EPR77677.1 - 0.00084 18.2 0.3 0.13 10.9 0.4 2.8 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EPR77677.1 - 0.0019 17.4 0.0 0.0048 16.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DMAP_binding PF06464.6 EPR77677.1 - 0.048 14.2 0.6 0.14 12.7 0.4 1.8 1 0 0 1 1 1 0 DMAP1-binding Domain SSFA2_C PF14723.1 EPR77678.1 - 0.068 12.9 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus AsnA PF03590.10 EPR77679.1 - 1.9e-38 132.2 4.6 2.3e-24 86.1 0.0 3.5 1 1 3 4 4 4 3 Aspartate-ammonia ligase Put_DNA-bind_N PF06971.8 EPR77679.1 - 0.11 12.2 0.5 18 5.1 0.0 2.8 2 1 1 3 3 3 0 Putative DNA-binding protein N-terminus DUF1754 PF08555.5 EPR77679.1 - 0.14 12.7 0.1 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) AsnA PF03590.10 EPR77680.1 - 1e-25 90.6 0.0 1.2e-25 90.3 0.0 1.0 1 0 0 1 1 1 1 Aspartate-ammonia ligase DUF3573 PF12097.3 EPR77680.1 - 0.13 10.8 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LRR_8 PF13855.1 EPR77683.1 - 1.3e-23 82.5 40.7 2.3e-08 33.6 2.7 8.3 5 3 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 EPR77683.1 - 2.1e-23 81.4 50.8 2.4e-08 33.4 5.1 8.8 8 2 0 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77683.1 - 7.3e-08 31.4 29.5 0.036 14.0 0.9 9.5 9 2 1 10 10 10 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR77683.1 - 0.0056 16.6 18.0 13 6.5 0.1 9.5 13 0 0 13 13 13 1 Leucine rich repeat LRR_9 PF14580.1 EPR77683.1 - 0.083 12.4 16.5 0.91 9.0 1.4 4.0 2 1 0 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.1 EPR77683.1 - 0.82 9.9 34.3 0.55 10.4 0.6 9.2 12 1 0 12 12 12 0 Leucine Rich repeat UPF0160 PF03690.8 EPR77684.1 - 4.8e-48 164.2 7.5 4.8e-28 98.5 0.9 3.0 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0160) Destabilase PF05497.7 EPR77685.1 - 0.046 13.8 0.5 0.094 12.8 0.3 1.5 1 0 0 1 1 1 0 Destabilase Ribosomal_S7 PF00177.16 EPR77686.1 - 1.8e-36 124.9 1.9 2.2e-36 124.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Spuma_A9PTase PF03539.9 EPR77689.1 - 0.0025 17.7 1.0 0.12 12.2 0.2 2.2 1 1 1 2 2 2 2 Spumavirus aspartic protease (A9) MBD_C PF14048.1 EPR77689.1 - 0.18 12.3 1.7 32 5.1 0.0 3.3 2 1 1 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 CDH PF02611.10 EPR77690.1 - 0.091 11.9 0.1 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 CDP-diacylglycerol pyrophosphatase Gti1_Pac2 PF09729.4 EPR77692.1 - 3.8 7.3 9.3 14 5.5 3.2 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family LRR_8 PF13855.1 EPR77693.1 - 1.9e-11 43.5 15.1 4.8e-08 32.6 4.4 7.7 7 2 2 9 9 9 3 Leucine rich repeat LRR_4 PF12799.2 EPR77693.1 - 7.2e-11 41.4 23.7 3.6e-05 23.2 0.2 9.9 6 3 4 10 10 10 5 Leucine Rich repeats (2 copies) Rota_NS6 PF04866.7 EPR77693.1 - 0.15 12.0 3.9 0.26 11.3 0.1 3.0 2 1 0 3 3 3 0 Rotavirus non-structural protein 6 TGT PF01702.13 EPR77694.1 - 2.8e-77 259.2 0.1 3.8e-77 258.7 0.1 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase DUF3596 PF12167.3 EPR77694.1 - 0.033 13.7 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) GlutR_dimer PF00745.15 EPR77695.1 - 0.1 12.5 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain ATP-synt_C PF00137.16 EPR77696.1 - 4.4e-11 42.5 17.8 1.6e-06 27.8 1.1 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF2897 PF11446.3 EPR77696.1 - 0.29 10.9 0.3 0.29 10.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DUF1049 PF06305.6 EPR77696.1 - 0.3 10.5 0.1 0.3 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FtsX PF02687.16 EPR77696.1 - 0.79 9.4 18.5 0.11 12.2 1.6 2.3 2 0 0 2 2 2 0 FtsX-like permease family HRDC PF00570.18 EPR77697.1 - 0.007 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain 2OG-Fe_Oxy_2 PF10014.4 EPR77697.1 - 0.051 12.9 1.3 0.23 10.8 0.1 2.1 2 0 0 2 2 2 0 2OG-Fe dioxygenase Guanylate_kin PF00625.16 EPR77699.1 - 7.4e-29 100.4 2.4 8.5e-29 100.2 1.7 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EPR77699.1 - 7.9e-10 39.1 1.3 1.1e-09 38.7 0.6 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR77699.1 - 3.9e-08 34.1 0.4 7.7e-08 33.1 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPR77699.1 - 2e-07 31.0 0.0 7.2e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPR77699.1 - 0.00038 20.7 0.4 0.00059 20.1 0.2 1.6 1 1 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EPR77699.1 - 0.00069 19.3 0.0 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPR77699.1 - 0.00075 19.3 0.8 0.0013 18.6 0.2 1.7 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EPR77699.1 - 0.0016 17.8 2.5 0.25 10.6 0.0 2.9 1 1 1 3 3 3 1 Thymidylate kinase PRK PF00485.13 EPR77699.1 - 0.0017 17.9 0.1 0.0032 17.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EPR77699.1 - 0.0018 18.3 0.1 0.0039 17.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EPR77699.1 - 0.0022 18.4 0.0 0.0048 17.3 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPR77699.1 - 0.0025 17.7 0.2 0.0044 16.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPR77699.1 - 0.0062 16.5 0.0 0.011 15.6 0.0 1.6 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EPR77699.1 - 0.0064 15.6 0.2 0.022 13.8 0.0 1.9 2 2 0 2 2 2 1 Zeta toxin T2SE PF00437.15 EPR77699.1 - 0.0072 15.2 0.2 0.016 14.1 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.10 EPR77699.1 - 0.0086 14.8 0.8 0.023 13.4 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EPR77699.1 - 0.01 15.3 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EPR77699.1 - 0.013 15.2 0.8 0.035 13.8 0.2 1.9 1 1 1 2 2 2 0 NTPase ADK PF00406.17 EPR77699.1 - 0.015 15.2 0.5 5.3 6.9 0.2 2.4 2 1 0 2 2 2 0 Adenylate kinase AAA_10 PF12846.2 EPR77699.1 - 0.016 14.6 0.7 0.016 14.6 0.5 1.5 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 EPR77699.1 - 0.022 14.4 0.1 0.063 12.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EPR77699.1 - 0.024 14.8 0.1 0.036 14.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EPR77699.1 - 0.037 13.4 0.1 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_32 PF13654.1 EPR77699.1 - 0.061 11.9 1.2 0.087 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPR77699.1 - 0.062 12.4 0.1 0.11 11.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DEAD PF00270.24 EPR77699.1 - 0.065 12.7 0.0 0.065 12.7 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 EPR77699.1 - 0.065 13.4 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.5 EPR77699.1 - 0.075 12.2 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit APS_kinase PF01583.15 EPR77699.1 - 0.081 12.5 0.1 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase PhoH PF02562.11 EPR77699.1 - 0.089 12.0 0.1 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.14 EPR77699.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EPR77699.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 EPR77699.1 - 0.13 12.2 7.9 0.25 11.2 5.5 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPR77699.1 - 0.13 11.7 1.6 0.3 10.6 0.2 2.0 1 1 1 2 2 2 0 AAA domain HEPN PF05168.9 EPR77699.1 - 0.38 10.6 3.6 0.19 11.6 0.7 1.7 2 0 0 2 2 2 0 HEPN domain AAA_23 PF13476.1 EPR77699.1 - 0.93 9.7 13.1 2 8.7 9.1 1.5 1 1 0 1 1 1 0 AAA domain C2 PF00168.25 EPR77700.1 - 2.4e-18 65.7 0.8 1.9e-10 40.4 0.0 3.9 3 0 0 3 3 3 3 C2 domain SAF_2 PF13144.1 EPR77700.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 SAF-like Bromo_MP PF01573.11 EPR77701.1 - 0.071 12.0 3.6 0.099 11.6 2.5 1.1 1 0 0 1 1 1 0 Bromovirus movement protein DDHD PF02862.12 EPR77701.1 - 0.096 12.4 1.5 0.11 12.2 1.1 1.2 1 0 0 1 1 1 0 DDHD domain ETRAMP PF09716.5 EPR77701.1 - 0.1 12.5 4.6 0.23 11.4 3.2 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAGA_bind PF06217.7 EPR77701.1 - 0.12 12.3 4.8 0.15 12.0 3.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3899 PF13038.1 EPR77701.1 - 0.15 12.2 0.5 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Med19 PF10278.4 EPR77701.1 - 0.24 11.0 12.0 0.44 10.2 8.3 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.6 EPR77701.1 - 0.3 10.7 16.2 0.53 9.9 11.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U1snRNP70_N PF12220.3 EPR77701.1 - 0.62 10.4 0.1 0.62 10.4 0.0 2.3 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Vfa1 PF08432.5 EPR77701.1 - 1.1 9.2 14.4 1.7 8.6 10.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EPR77701.1 - 5.6 4.8 9.6 7.3 4.4 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Coatomer_WDAD PF04053.9 EPR77702.1 - 6.8e-07 28.4 3.9 6.8e-07 28.4 2.7 2.6 3 1 0 3 3 3 1 Coatomer WD associated region PPR PF01535.15 EPR77702.1 - 0.00082 19.1 0.1 0.41 10.7 0.0 3.4 2 0 0 2 2 2 1 PPR repeat COPI_C PF06957.6 EPR77702.1 - 0.011 14.3 0.1 0.011 14.3 0.1 2.3 1 1 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus TPR_19 PF14559.1 EPR77702.1 - 0.02 15.1 0.4 1 9.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 EPR77702.1 - 0.031 14.2 0.2 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 PPR repeat family LRR_4 PF12799.2 EPR77704.1 - 1.1e-32 111.0 72.0 1e-06 28.2 1.5 8.8 8 1 1 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77704.1 - 1.3e-25 88.9 66.6 3.4e-07 29.9 5.0 7.4 4 3 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EPR77704.1 - 3.4e-18 62.8 66.6 0.022 14.7 0.0 14.5 13 1 2 15 15 15 11 Leucine Rich Repeat LRR_7 PF13504.1 EPR77704.1 - 1.4e-14 51.6 38.3 2.2 8.8 0.0 13.9 15 0 0 15 15 15 6 Leucine rich repeat LRR_6 PF13516.1 EPR77704.1 - 6.7e-05 22.5 61.2 3.6 7.9 0.1 13.2 15 0 0 15 15 15 7 Leucine Rich repeat LRR_2 PF07723.8 EPR77704.1 - 0.14 12.6 14.4 1.6 9.3 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat SMC_N PF02463.14 EPR77705.1 - 2.3e-06 26.9 0.2 2.5e-06 26.8 0.1 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPR77705.1 - 1.2e-05 25.3 0.0 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPR77705.1 - 0.00014 21.0 0.6 0.00015 20.9 0.3 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_13 PF13166.1 EPR77705.1 - 0.0029 16.1 1.1 0.0032 15.9 0.8 1.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPR77705.1 - 0.036 14.3 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter DUF3256 PF11644.3 EPR77706.1 - 0.032 13.7 2.3 0.055 12.9 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3256) F_actin_bind PF08919.5 EPR77706.1 - 0.048 13.3 0.2 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 F-actin binding CobS PF02654.10 EPR77706.1 - 0.09 12.3 1.5 1.8 8.1 0.0 2.7 2 1 1 3 3 3 0 Cobalamin-5-phosphate synthase LRR_4 PF12799.2 EPR77707.1 - 1.3e-10 40.6 14.7 1.3e-05 24.6 3.0 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77707.1 - 1e-09 38.0 11.8 2.5e-05 23.9 2.4 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPR77707.1 - 1.3e-06 27.6 11.9 0.13 12.4 0.1 4.6 4 1 0 4 4 4 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR77707.1 - 3e-05 23.5 2.3 0.3 11.4 0.1 4.4 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EPR77707.1 - 0.00049 19.8 9.3 0.033 14.2 0.4 4.2 4 0 0 4 4 4 1 Leucine Rich repeat Glyco_hydro_28 PF00295.12 EPR77707.1 - 0.056 12.3 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 LRR_4 PF12799.2 EPR77708.1 - 1.2e-19 69.4 23.0 2.6e-09 36.4 1.2 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77708.1 - 1e-15 55.3 21.5 0.0012 18.5 0.1 5.2 3 1 2 5 5 5 5 Leucine Rich Repeat LRR_8 PF13855.1 EPR77708.1 - 1.7e-15 56.5 24.1 4.8e-09 35.8 7.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 EPR77708.1 - 1.1e-14 51.9 10.5 0.044 13.9 0.5 5.3 5 0 0 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 EPR77708.1 - 4.3e-11 41.6 21.7 0.057 13.5 0.5 5.2 5 0 0 5 5 5 5 Leucine Rich repeat LRR_9 PF14580.1 EPR77708.1 - 0.011 15.2 5.5 0.022 14.3 3.7 1.4 1 1 0 1 1 1 0 Leucine-rich repeat Beta_helix PF13229.1 EPR77708.1 - 0.082 12.6 7.9 0.11 12.2 5.5 1.3 1 0 0 1 1 1 0 Right handed beta helix region DUF4340 PF14238.1 EPR77708.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4340) LRR_2 PF07723.8 EPR77708.1 - 0.16 12.5 2.9 56 4.4 0.1 4.2 4 1 1 5 5 5 0 Leucine Rich Repeat DUF1904 PF08921.6 EPR77709.1 - 0.098 12.7 1.5 3.3 7.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) SEA PF01390.15 EPR77709.1 - 0.1 12.3 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SEA domain DUF1348 PF07080.6 EPR77709.1 - 0.15 11.8 0.7 0.22 11.3 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1348) DUF843 PF05814.6 EPR77709.1 - 0.81 9.5 3.7 1 9.1 0.4 2.3 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) LAGLIDADG_1 PF00961.14 EPR77710.1 - 0.12 12.9 6.6 2 9.0 2.1 2.2 1 1 1 2 2 2 0 LAGLIDADG endonuclease SNF2_N PF00176.18 EPR77711.1 - 2.1e-05 23.4 2.4 2.7e-05 23.1 1.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain RNA_pol_Rpb1_5 PF04998.12 EPR77711.1 - 5.3 6.2 12.0 6.4 5.9 8.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 LRR_4 PF12799.2 EPR77712.1 - 3.9e-09 35.9 15.8 0.00013 21.4 0.2 3.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77712.1 - 8.1e-09 35.1 7.6 0.00011 21.9 1.1 3.0 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR77712.1 - 4.1e-08 32.1 15.5 0.017 15.0 0.0 5.5 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EPR77712.1 - 8.1e-05 22.3 13.7 0.59 10.3 0.3 5.0 4 1 1 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 EPR77712.1 - 0.0007 19.3 9.7 1.7 9.2 0.2 5.0 6 0 0 6 6 6 3 Leucine rich repeat LRR_5 PF13306.1 EPR77712.1 - 0.059 13.0 7.2 0.12 12.0 4.9 1.7 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EPR77714.1 - 1.7e-16 59.7 23.0 1.6e-07 30.9 1.4 3.0 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 EPR77714.1 - 7.2e-14 51.0 14.8 1.6e-06 27.5 4.0 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77714.1 - 2.6e-08 32.7 12.6 0.0097 15.8 0.1 5.3 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EPR77714.1 - 1.5e-05 24.5 9.6 0.0058 16.5 0.2 4.5 4 1 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EPR77714.1 - 4e-05 23.1 6.0 0.3 11.4 0.1 4.4 5 0 0 5 5 5 2 Leucine rich repeat LRR_5 PF13306.1 EPR77714.1 - 0.0051 16.5 6.0 0.011 15.4 4.2 1.7 1 1 0 1 1 1 1 Leucine rich repeats (6 copies) DUF3557 PF12078.3 EPR77714.1 - 0.0083 15.8 4.5 0.012 15.3 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3557) LRR_2 PF07723.8 EPR77714.1 - 0.22 12.0 1.2 37 5.0 0.1 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.2 EPR77715.1 - 2.2e-27 94.1 49.8 2.3e-07 30.2 0.4 7.2 5 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77715.1 - 6.3e-22 77.1 39.7 2.1e-06 27.3 0.7 6.1 3 2 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EPR77715.1 - 2.1e-18 63.5 48.4 0.028 14.4 0.0 11.0 9 1 2 11 11 11 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR77715.1 - 7.1e-11 40.4 26.5 0.84 10.0 0.0 10.5 11 0 0 11 11 11 5 Leucine rich repeat LRR_6 PF13516.1 EPR77715.1 - 9.8e-11 40.5 31.9 0.14 12.3 0.1 9.8 10 0 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.1 EPR77716.1 - 1.3e-21 76.1 39.2 2.6e-07 30.2 0.3 4.5 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EPR77716.1 - 1.6e-20 72.2 59.4 2.4e-06 27.0 2.5 4.6 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77716.1 - 1.5e-17 60.9 27.4 0.0041 16.9 1.1 7.7 6 1 1 7 7 7 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR77716.1 - 5.1e-10 37.8 18.6 0.45 10.9 0.5 7.3 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EPR77716.1 - 7.5e-08 31.6 27.8 0.035 14.1 1.3 7.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_5 PF13306.1 EPR77716.1 - 9.7e-06 25.3 18.4 0.00064 19.4 6.8 2.8 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) bPH_3 PF14470.1 EPR77716.1 - 0.038 14.2 0.2 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial PH domain Phage_DsbA PF11126.3 EPR77716.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DsbA DUF4340 PF14238.1 EPR77716.1 - 0.072 12.7 0.2 0.34 10.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4340) RNA_pol_L_2 PF13656.1 EPR77717.1 - 2.5e-16 58.8 1.0 3e-16 58.6 0.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain UXS1_N PF11803.3 EPR77717.1 - 0.096 12.4 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal PI31_Prot_N PF11566.3 EPR77717.1 - 0.11 12.0 1.0 0.14 11.7 0.7 1.1 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal Annexin PF00191.15 EPR77717.1 - 0.16 11.9 0.9 8.9 6.2 0.0 2.7 2 1 1 3 3 3 0 Annexin Mucin PF01456.12 EPR77718.1 - 0.0075 16.0 8.7 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.6 EPR77718.1 - 0.027 12.4 9.1 0.28 9.0 0.1 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EPR77718.1 - 0.13 12.0 6.0 0.23 11.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_L3 PF00297.17 EPR77719.1 - 1.3e-83 280.4 5.3 1.6e-83 280.1 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 EF-hand_7 PF13499.1 EPR77720.1 - 4.7e-08 33.0 1.7 1.6e-07 31.3 0.2 2.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 EPR77720.1 - 7.3e-05 22.2 5.5 0.063 12.9 0.2 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 EPR77720.1 - 0.00013 21.5 4.8 0.035 13.9 0.0 4.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 EPR77720.1 - 0.00065 18.8 6.7 0.021 14.0 0.0 3.6 4 0 0 4 4 4 2 EF hand eRF1_2 PF03464.10 EPR77721.1 - 1.4e-32 112.7 0.0 2.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPR77721.1 - 2.2e-25 89.1 0.1 4.6e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EPR77721.1 - 3.3e-18 65.5 0.0 6.4e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 MMR_HSR1 PF01926.18 EPR77722.1 - 2.8e-22 78.8 2.4 4.1e-21 75.0 0.1 2.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 EPR77722.1 - 1.5e-18 66.3 0.2 3.3e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EPR77722.1 - 5.2e-10 38.8 1.0 1.3e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPR77722.1 - 7.2e-05 22.6 0.4 0.24 11.1 0.0 3.1 2 1 1 3 3 3 2 Dynamin family Clathrin PF00637.15 EPR77722.1 - 0.00034 20.2 0.2 0.00099 18.7 0.2 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS GTP_EFTU PF00009.22 EPR77722.1 - 0.0013 18.2 1.4 1.4 8.3 1.0 4.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EPR77722.1 - 0.0037 16.0 0.0 0.0095 14.7 0.0 1.6 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EPR77722.1 - 0.0056 17.1 0.0 0.022 15.2 0.0 2.0 1 1 1 2 2 2 1 Miro-like protein KTI12 PF08433.5 EPR77722.1 - 0.0093 15.1 1.4 1.1 8.3 0.0 3.3 3 1 0 3 3 3 1 Chromatin associated protein KTI12 DUF258 PF03193.11 EPR77722.1 - 0.012 14.7 0.1 0.023 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPR77722.1 - 0.018 15.2 0.7 1.2 9.2 0.5 2.7 1 1 0 1 1 1 0 AAA domain tRNA_U5-meth_tr PF05958.6 EPR77722.1 - 0.018 13.7 0.1 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase AAA_28 PF13521.1 EPR77722.1 - 0.019 14.8 0.1 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPR77722.1 - 0.073 13.8 0.3 0.25 12.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EPR77722.1 - 0.11 11.7 1.3 1.6 7.8 0.0 2.8 2 1 1 3 3 3 0 ADP-ribosylation factor family Metallophos PF00149.23 EPR77724.1 - 8.9e-44 149.2 0.4 1.2e-43 148.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP_bind_1 PF03029.12 EPR77727.1 - 2.2e-21 76.4 0.1 1.7e-11 44.1 0.0 2.0 1 1 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EPR77727.1 - 2.1e-05 25.3 0.1 3e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPR77727.1 - 3.4e-05 23.7 0.1 8.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPR77727.1 - 0.00029 20.9 0.0 0.00039 20.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR77727.1 - 0.0027 17.9 0.2 0.0042 17.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EPR77727.1 - 0.0073 15.2 0.0 0.0099 14.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EPR77727.1 - 0.027 13.5 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EPR77727.1 - 0.03 14.1 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPR77727.1 - 0.032 13.9 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPR77727.1 - 0.045 13.9 0.3 0.1 12.7 0.2 1.9 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EPR77727.1 - 0.045 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPR77727.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 EPR77727.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MobB PF03205.9 EPR77727.1 - 0.096 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FHIPEP PF00771.15 EPR77729.1 - 0.0022 16.4 2.5 0.0027 16.1 1.7 1.0 1 0 0 1 1 1 1 FHIPEP family GvpK PF05121.7 EPR77729.1 - 0.19 11.5 10.4 1.8 8.4 1.2 2.3 2 0 0 2 2 2 0 Gas vesicle protein K DUF4404 PF14357.1 EPR77729.1 - 0.99 9.8 10.7 0.53 10.7 1.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) THF_DHG_CYH PF00763.18 EPR77730.1 - 0.014 15.4 0.6 0.089 12.8 0.1 2.5 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ABC_tran PF00005.22 EPR77731.1 - 1.7e-13 51.0 0.1 1.9e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EPR77731.1 - 0.0014 18.0 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPR77731.1 - 0.0018 17.5 0.4 0.0029 16.8 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPR77731.1 - 0.0022 17.5 0.1 0.0051 16.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EPR77731.1 - 0.0023 16.8 0.1 0.0032 16.4 0.0 1.3 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EPR77731.1 - 0.0026 18.1 1.5 0.074 13.3 1.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR77731.1 - 0.0044 17.8 0.0 0.0065 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPR77731.1 - 0.0059 16.7 0.2 0.0072 16.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPR77731.1 - 0.0072 16.0 0.1 0.009 15.7 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EPR77731.1 - 0.0073 16.3 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EPR77731.1 - 0.0095 16.0 0.1 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase cobW PF02492.14 EPR77731.1 - 0.0096 15.3 0.1 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EPR77731.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EPR77731.1 - 0.013 15.0 0.2 0.02 14.4 0.1 1.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EPR77731.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Rad17 PF03215.10 EPR77731.1 - 0.027 13.1 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EPR77731.1 - 0.031 13.9 0.4 0.047 13.3 0.3 1.3 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EPR77731.1 - 0.033 13.6 0.4 0.048 13.1 0.1 1.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EPR77731.1 - 0.035 13.8 0.1 0.062 13.0 0.1 1.4 1 0 0 1 1 1 0 NTPase Guanylate_kin PF00625.16 EPR77731.1 - 0.036 13.5 0.4 0.061 12.7 0.3 1.6 1 1 0 1 1 1 0 Guanylate kinase AAA_10 PF12846.2 EPR77731.1 - 0.037 13.4 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Pox_A32 PF04665.7 EPR77731.1 - 0.039 13.2 0.2 0.077 12.2 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.1 EPR77731.1 - 0.045 13.3 0.9 0.064 12.8 0.6 1.6 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EPR77731.1 - 0.05 12.7 0.1 0.065 12.3 0.1 1.1 1 0 0 1 1 1 0 KaiC UPF0079 PF02367.12 EPR77731.1 - 0.069 12.7 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EPR77731.1 - 0.07 13.0 0.1 0.097 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EPR77731.1 - 0.07 12.7 0.7 0.1 12.1 0.5 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EPR77731.1 - 0.08 12.9 0.5 0.18 11.7 0.4 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EPR77731.1 - 0.086 11.6 1.5 0.18 10.6 1.0 1.7 1 1 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 EPR77731.1 - 0.095 11.6 0.6 0.12 11.3 0.1 1.4 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.24 EPR77731.1 - 0.11 12.7 0.4 0.13 12.4 0.3 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EPR77731.1 - 0.12 11.8 0.5 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 EPR77731.1 - 0.15 11.2 1.0 2.5 7.2 0.7 2.3 1 1 0 1 1 1 0 PhoH-like protein DUF2215 PF10225.4 EPR77732.1 - 0.051 13.0 0.6 0.072 12.5 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Glycos_transf_1 PF00534.15 EPR77733.1 - 4.7e-29 101.0 0.2 2.5e-28 98.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPR77733.1 - 6.8e-18 65.0 0.0 2.3e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EPR77733.1 - 1.4e-16 61.0 0.0 1.8e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain PIGA PF08288.7 EPR77733.1 - 2.7e-16 59.7 1.4 3.9e-16 59.2 0.3 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_4 PF13692.1 EPR77733.1 - 5.6e-11 42.7 0.0 8.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EPR77733.1 - 3.1e-06 27.0 0.8 3.1e-06 27.0 0.6 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EPR77733.1 - 6.2e-05 23.1 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_hydro_31 PF01055.21 EPR77733.1 - 0.073 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 LAGLIDADG_WhiA PF14527.1 EPR77734.1 - 1.4 8.8 10.6 8.9 6.2 0.1 4.0 4 0 0 4 4 4 0 WhiA LAGLIDADG-like domain FNIP PF05725.7 EPR77735.1 - 0.12 12.3 0.8 0.53 10.2 0.3 2.4 1 1 1 2 2 2 0 FNIP Repeat LSM PF01423.17 EPR77736.1 - 3.3e-14 52.1 0.3 4.8e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 LSM domain AKAP2_C PF15304.1 EPR77737.1 - 0.0013 18.4 0.5 0.0017 18.0 0.3 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus Apc3 PF12895.2 EPR77737.1 - 0.074 13.1 0.3 0.074 13.1 0.2 4.1 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_4 PF12799.2 EPR77738.1 - 4.6e-23 80.3 43.7 2.3e-08 33.4 2.1 5.8 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77738.1 - 1.3e-22 79.3 35.6 4.1e-07 29.6 1.6 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EPR77738.1 - 2.1e-11 42.1 37.0 0.018 15.0 0.2 10.0 9 1 2 11 11 11 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR77738.1 - 5.3e-10 37.8 20.9 0.64 10.4 0.1 9.6 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 EPR77738.1 - 1.5e-05 24.6 39.3 3.1 8.1 0.3 9.4 8 1 2 10 10 10 6 Leucine Rich repeat LRR_9 PF14580.1 EPR77738.1 - 0.011 15.2 8.4 0.054 13.0 1.1 3.1 1 1 2 3 3 3 0 Leucine-rich repeat Kelch_4 PF13418.1 EPR77738.1 - 0.1 12.3 0.4 46 3.9 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Erf4 PF10256.4 EPR77739.1 - 0.31 10.9 1.8 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Alpha-2-MRAP_N PF06400.6 EPR77740.1 - 0.026 14.2 0.3 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain DAN PF03045.10 EPR77740.1 - 0.047 13.1 0.1 0.087 12.2 0.1 1.4 1 0 0 1 1 1 0 DAN domain Plus-3 PF03126.13 EPR77740.1 - 0.084 12.9 0.2 2.7 8.0 0.0 2.4 2 1 0 2 2 2 0 Plus-3 domain THOC7 PF05615.8 EPR77743.1 - 0.37 11.0 6.5 0.59 10.4 4.5 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2482 PF10655.4 EPR77743.1 - 5.6 7.0 9.8 3.9 7.6 0.2 2.9 2 1 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) Abhydrolase_5 PF12695.2 EPR77745.1 - 2.7e-07 30.4 0.0 5.8e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPR77745.1 - 0.0023 17.8 0.0 0.061 13.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EPR77745.1 - 0.05 13.2 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_1 PF00561.15 EPR77745.1 - 0.12 11.8 1.7 1.7 8.1 0.0 2.8 3 1 1 4 4 4 0 alpha/beta hydrolase fold Plasmodium_Vir PF05795.6 EPR77746.1 - 0.016 14.4 3.4 0.02 14.1 2.3 1.3 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_S5_C PF03719.10 EPR77747.1 - 7.6e-20 69.9 0.4 2.2e-19 68.5 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EPR77747.1 - 7.9e-16 57.5 2.8 7.9e-16 57.5 2.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DUF3995 PF13160.1 EPR77748.1 - 0.42 10.6 7.2 0.031 14.3 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Yip1 PF04893.12 EPR77748.1 - 1.8 8.0 26.9 0.33 10.4 14.5 1.9 1 1 1 2 2 2 0 Yip1 domain GDA1_CD39 PF01150.12 EPR77749.1 - 9e-33 113.4 3.8 2.2e-29 102.2 0.2 3.3 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family TFIIA PF03153.8 EPR77751.1 - 7.4e-24 85.3 1.7 9.6e-18 65.2 0.3 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF3617 PF12276.3 EPR77751.1 - 0.064 12.7 0.3 0.093 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) DUF4145 PF13643.1 EPR77751.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) PAE PF03283.8 EPR77752.1 - 0.0096 14.5 1.1 0.011 14.3 0.1 1.6 2 0 0 2 2 2 1 Pectinacetylesterase Urm1 PF09138.6 EPR77752.1 - 0.17 12.0 3.9 0.085 12.9 0.3 2.3 2 0 0 2 2 2 0 Urm1 (Ubiquitin related modifier) zf-C2H2_4 PF13894.1 EPR77753.1 - 0.01 16.1 7.5 0.86 10.0 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPR77753.1 - 0.15 12.4 14.4 0.94 9.9 1.7 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type PCI PF01399.22 EPR77754.1 - 2.8e-07 30.7 3.7 2.8e-07 30.7 2.5 2.8 2 1 2 4 4 4 1 PCI domain YejG PF13989.1 EPR77754.1 - 2.1 8.4 7.4 0.76 9.8 0.1 3.3 3 0 0 3 3 3 0 YejG-like protein ThiF PF00899.16 EPR77755.1 - 4.6e-56 188.3 3.2 1.9e-37 128.1 0.1 3.5 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EPR77755.1 - 1.2e-29 101.6 7.1 2.6e-25 87.7 0.2 3.4 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EPR77755.1 - 9.1e-24 84.0 3.6 9.1e-24 84.0 2.5 2.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EPR77755.1 - 3.8e-19 67.7 0.2 8.3e-19 66.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EPR77755.1 - 0.0027 17.9 1.4 0.38 11.0 0.0 3.6 3 1 0 3 3 3 1 Putative NAD(P)-binding RNase_PH_C PF03725.10 EPR77757.1 - 0.0044 16.9 0.2 0.012 15.4 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 EPR77757.1 - 0.012 15.9 0.2 0.027 14.7 0.1 1.7 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 ABC2_membrane_3 PF12698.2 EPR77757.1 - 1.2 8.0 5.0 1.6 7.7 3.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein LRR_4 PF12799.2 EPR77758.1 - 3.8e-21 74.2 83.2 2.8e-07 29.9 3.7 10.9 7 1 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77758.1 - 4.2e-21 74.4 65.8 4e-10 39.3 5.7 9.2 5 2 4 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 EPR77758.1 - 1.2e-08 33.8 71.7 0.13 12.3 0.0 15.4 15 1 0 15 15 15 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR77758.1 - 6.9e-07 28.4 42.5 0.44 10.9 0.0 13.8 15 0 0 15 15 15 2 Leucine rich repeat LRR_6 PF13516.1 EPR77758.1 - 2 8.7 57.4 1.2 9.4 0.0 12.4 12 1 1 13 13 13 0 Leucine Rich repeat RNA_pol_Rpb5_C PF01191.14 EPR77759.1 - 0.074 12.6 1.4 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Peptidase_C50 PF03568.12 EPR77760.1 - 0.0014 17.3 0.2 0.0014 17.3 0.2 1.7 2 0 0 2 2 2 1 Peptidase family C50 LXG PF04740.7 EPR77760.1 - 0.0075 16.0 4.1 0.0092 15.7 2.9 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily LRR_4 PF12799.2 EPR77761.1 - 4.8e-11 42.0 14.8 3.7e-07 29.6 1.9 9.1 6 5 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77761.1 - 1.8e-07 30.8 5.7 1.8e-07 30.8 4.0 7.3 9 0 0 9 9 9 2 Leucine rich repeat LRR_1 PF00560.28 EPR77761.1 - 0.00042 19.9 30.6 0.002 17.8 0.1 10.4 8 4 1 9 9 9 1 Leucine Rich Repeat LRR_7 PF13504.1 EPR77761.1 - 0.077 13.2 13.8 2 8.9 0.0 8.1 9 1 0 9 9 9 0 Leucine rich repeat LRR_6 PF13516.1 EPR77761.1 - 1.1 9.5 0.0 1.1 9.5 0.0 8.4 9 1 1 10 10 10 0 Leucine Rich repeat SK_channel PF03530.9 EPR77762.1 - 0.06 13.1 0.4 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Tfb4 PF03850.9 EPR77763.1 - 9.8e-08 31.5 17.1 2e-06 27.2 10.0 2.8 1 1 1 2 2 2 2 Transcription factor Tfb4 RRM_2 PF04059.7 EPR77764.1 - 3e-40 136.1 1.2 3e-40 136.1 0.8 2.0 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 EPR77764.1 - 0.0015 18.0 0.1 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PSDC PF12588.3 EPR77764.1 - 0.028 14.0 0.5 0.054 13.1 0.3 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase zf-RING_2 PF13639.1 EPR77765.1 - 1.4e-05 24.8 9.2 0.00011 21.9 3.4 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPR77765.1 - 0.011 15.4 3.2 0.026 14.1 2.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR77765.1 - 0.041 13.5 7.7 0.12 12.0 5.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EPR77765.1 - 0.21 11.6 8.7 0.22 11.5 2.9 2.9 3 1 0 3 3 3 0 RING-like domain zf-RING_5 PF14634.1 EPR77765.1 - 0.24 11.1 7.1 0.62 9.8 4.9 1.8 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EPR77765.1 - 0.51 10.0 10.1 0.12 12.0 3.3 2.5 3 0 0 3 3 3 0 PHD-finger zf-rbx1 PF12678.2 EPR77765.1 - 0.55 10.3 7.0 13 5.9 5.3 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPR77765.1 - 1.1 9.3 9.5 0.39 10.7 4.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR77766.1 - 0.022 14.4 4.8 0.05 13.3 3.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPR77766.1 - 0.17 11.5 4.1 0.43 10.2 2.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPR77766.1 - 0.22 11.4 5.5 1.1 9.1 4.1 2.1 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 EPR77766.1 - 0.25 11.0 9.0 0.072 12.7 4.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EPR77766.1 - 0.26 10.9 4.6 0.59 9.8 3.2 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EPR77766.1 - 1.4 8.9 6.0 5.2 7.1 4.2 2.0 1 1 0 1 1 1 0 RING-like domain Choline_transpo PF04515.7 EPR77768.1 - 5.5e-14 51.6 2.9 5.9e-14 51.5 2.0 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter Choline_transpo PF04515.7 EPR77769.1 - 0.041 12.6 20.6 0.038 12.7 12.6 2.0 1 1 0 1 1 1 0 Plasma-membrane choline transporter Choline_transpo PF04515.7 EPR77770.1 - 7.9e-27 93.8 38.8 2.2e-26 92.4 26.9 1.6 1 1 0 1 1 1 1 Plasma-membrane choline transporter HA2 PF04408.18 EPR77771.1 - 1.3e-14 54.0 1.5 2.6e-13 49.8 0.0 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPR77771.1 - 3.4e-11 42.9 0.1 1.5e-10 40.8 0.1 2.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPR77771.1 - 5.3e-10 39.0 0.0 1.5e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPR77771.1 - 5.2e-06 26.0 0.9 0.042 13.3 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase T2SE PF00437.15 EPR77771.1 - 0.0039 16.1 0.1 0.0088 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPR77771.1 - 0.004 17.2 5.2 0.067 13.3 2.4 3.4 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPR77771.1 - 0.011 15.2 0.1 0.027 13.9 0.1 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SPASM PF13186.1 EPR77771.1 - 0.037 14.3 1.1 0.26 11.6 0.1 3.1 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain TrwB_AAD_bind PF10412.4 EPR77771.1 - 0.045 12.3 1.1 0.11 11.0 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 EPR77771.1 - 0.13 11.8 0.1 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EPR77771.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EPR77771.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SNARE PF05739.14 EPR77773.1 - 6.7e-10 38.5 0.4 6.7e-10 38.5 0.3 2.0 2 0 0 2 2 2 1 SNARE domain TraH PF06122.6 EPR77773.1 - 0.054 12.2 0.5 0.087 11.6 0.4 1.3 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein MCPsignal PF00015.16 EPR77773.1 - 0.063 12.8 1.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cucumo_coat PF00760.13 EPR77773.1 - 0.072 12.0 0.1 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Cucumovirus coat protein APP_N PF02177.11 EPR77773.1 - 0.11 12.4 0.3 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Laminin_II PF06009.7 EPR77773.1 - 0.13 11.9 3.7 2 8.1 0.1 2.6 2 2 0 2 2 2 0 Laminin Domain II MtrG PF04210.8 EPR77773.1 - 0.17 11.5 1.7 0.25 11.0 0.5 1.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cpn60_TCP1 PF00118.19 EPR77775.1 - 7.1e-121 404.1 15.4 8.2e-121 403.9 10.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Apc9 PF12856.2 EPR77776.1 - 0.019 15.0 1.5 0.038 14.0 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 DWNN PF08783.6 EPR77776.1 - 0.038 13.9 0.5 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 DWNN domain tRNA-synt_1b PF00579.20 EPR77777.1 - 8.6e-36 123.5 0.0 1.1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PAP_assoc PF03828.14 EPR77778.1 - 6.3e-08 32.4 3.4 2.7e-07 30.4 2.4 2.2 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPR77778.1 - 8.3e-07 29.2 1.4 8.3e-07 29.2 1.0 2.4 2 1 0 2 2 2 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EPR77778.1 - 0.0033 17.4 0.1 0.0064 16.5 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DUF1981 PF09324.5 EPR77778.1 - 0.035 13.6 0.0 0.16 11.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) AMP-binding PF00501.23 EPR77779.1 - 2.8e-77 259.8 0.0 4.1e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TMEM117 PF15113.1 EPR77779.1 - 0.039 12.5 0.2 0.039 12.5 0.1 1.8 2 0 0 2 2 2 0 TMEM117 protein family Kinesin PF00225.18 EPR77780.1 - 2.1e-81 273.2 8.0 2.1e-81 273.2 5.5 1.5 2 0 0 2 2 2 1 Kinesin motor domain PhoH PF02562.11 EPR77780.1 - 0.095 11.9 2.3 0.93 8.6 0.1 2.6 3 0 0 3 3 3 0 PhoH-like protein Gpi1 PF05024.10 EPR77782.1 - 2e-12 47.1 10.0 1.1e-08 34.9 3.4 2.1 1 1 1 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Gemini_V1 PF01524.12 EPR77782.1 - 0.026 14.4 0.2 0.052 13.5 0.1 1.6 1 0 0 1 1 1 0 Geminivirus V1 protein RDD PF06271.7 EPR77782.1 - 0.43 10.4 10.2 0.74 9.7 0.9 2.3 1 1 1 2 2 2 0 RDD family PI3_PI4_kinase PF00454.22 EPR77783.1 - 0.00023 20.7 2.9 0.00031 20.3 2.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Peptidase_C65 PF10275.4 EPR77784.1 - 2.4e-21 76.1 10.8 3.2e-21 75.8 7.5 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EPR77784.1 - 5.6e-05 23.7 0.0 0.00026 21.5 0.0 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease NAAA-beta PF15508.1 EPR77784.1 - 0.026 14.8 1.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BBS2_Mid PF14783.1 EPR77785.1 - 0.02 14.6 1.0 3 7.6 0.1 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Alpha-amyl_C PF09071.5 EPR77785.1 - 0.096 12.4 0.5 0.2 11.4 0.3 1.6 1 1 0 1 1 1 0 Alpha-amylase, C terminal Tospo_nucleocap PF01533.11 EPR77785.1 - 1 8.5 6.3 1.4 8.1 3.6 1.7 1 1 1 2 2 2 0 Tospovirus nucleocapsid protein DUF1221 PF06760.6 EPR77786.1 - 0.032 13.4 0.4 0.039 13.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) YcfA PF07927.7 EPR77786.1 - 2.2 8.2 4.7 1.6 8.6 0.9 2.0 2 1 0 2 2 2 0 YcfA-like protein LIF_OSM PF01291.12 EPR77787.1 - 0.19 11.6 3.5 0.82 9.5 0.1 2.3 1 1 1 2 2 2 0 LIF / OSM family Cytochrom_C_2 PF01322.15 EPR77787.1 - 1.8 9.1 8.4 0.37 11.3 1.8 2.5 1 1 1 2 2 2 0 Cytochrome C' NPV_P10 PF05531.7 EPR77787.1 - 2.5 8.3 10.8 2.7 8.3 3.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3086 PF11285.3 EPR77787.1 - 4.9 5.8 8.1 4.2 6.0 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) DUF3899 PF13038.1 EPR77787.1 - 5.5 7.2 6.3 1.2 9.3 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) DUF2463 PF09591.5 EPR77788.1 - 0.017 14.7 1.1 0.023 14.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) DUF2258 PF10015.4 EPR77788.1 - 0.065 13.0 1.9 0.12 12.2 0.1 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) RNA_pol_Rpb4 PF03874.11 EPR77788.1 - 0.082 12.9 6.2 0.091 12.7 3.8 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb4 DUF4485 PF14846.1 EPR77790.1 - 7e-05 22.4 1.8 0.12 12.1 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4485) DUF3298 PF11738.3 EPR77790.1 - 0.24 11.9 2.9 3.3 8.2 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3298) LRAT PF04970.8 EPR77792.1 - 0.12 12.2 1.2 0.14 12.0 0.8 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase C-term_anchor PF13461.1 EPR77792.1 - 5.8 7.4 8.4 2.2e+02 2.3 5.8 2.2 1 1 0 1 1 1 0 Cell-wall surface anchor repeat BRCT PF00533.21 EPR77793.1 - 0.1 12.7 2.7 0.25 11.5 0.1 2.4 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Skp1 PF01466.14 EPR77794.1 - 2.8e-06 27.2 0.2 6.8e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain zf-rbx1 PF12678.2 EPR77795.1 - 2.5e-20 72.3 20.2 3.3e-20 71.9 14.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPR77795.1 - 1.4e-17 63.2 15.2 1.6e-17 63.0 10.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EPR77795.1 - 9.1e-09 35.0 25.8 4.1e-08 32.9 17.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPR77795.1 - 5.4e-06 25.9 24.3 0.00045 19.8 3.9 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR77795.1 - 6.6e-05 22.8 5.9 6.6e-05 22.8 4.1 2.4 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR77795.1 - 0.00019 21.0 5.9 0.00019 21.0 4.1 2.7 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR77795.1 - 0.00033 20.3 15.7 0.00033 20.3 10.9 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 EPR77795.1 - 0.0032 17.2 9.6 0.0053 16.5 6.7 1.5 1 1 0 1 1 1 1 zf-RING of BARD1-type protein DUF2256 PF10013.4 EPR77795.1 - 0.04 13.6 4.1 0.04 13.6 2.8 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Sec20 PF03908.8 EPR77796.1 - 1.4e-05 24.7 2.3 1.4e-05 24.7 1.6 1.8 2 0 0 2 2 2 1 Sec20 DUF2688 PF10892.3 EPR77796.1 - 0.06 13.0 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Phage_min_cap2 PF06152.6 EPR77797.1 - 0.022 13.7 0.1 0.15 11.0 0.0 2.1 1 1 0 1 1 1 0 Phage minor capsid protein 2 FolB PF02152.13 EPR77797.1 - 0.057 13.5 2.1 4.6 7.4 0.1 3.2 2 1 1 3 3 3 0 Dihydroneopterin aldolase DUF4363 PF14276.1 EPR77797.1 - 0.066 12.9 12.0 0.28 10.8 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) U5_2-snRNA_bdg PF10597.4 EPR77797.1 - 0.076 12.6 0.3 2.3 7.8 0.0 2.6 3 0 0 3 3 3 0 U5-snRNA binding site 2 of PrP8 Prp18 PF02840.10 EPR77797.1 - 0.15 11.8 1.2 0.37 10.6 0.1 2.0 2 0 0 2 2 2 0 Prp18 domain NEP PF10167.4 EPR77797.1 - 0.16 11.6 2.8 3.1 7.5 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein Ku_PK_bind PF08785.6 EPR77797.1 - 0.47 10.3 3.9 0.92 9.4 1.4 2.5 2 1 0 2 2 2 0 Ku C terminal domain like Crust_neurohorm PF01147.12 EPR77797.1 - 0.63 9.3 10.8 2 7.7 0.4 3.2 3 0 0 3 3 3 0 Crustacean CHH/MIH/GIH neurohormone family DNA_pol_alpha_N PF12254.3 EPR77797.1 - 1.3 8.9 4.3 18 5.2 0.0 3.7 4 0 0 4 4 4 0 DNA polymerase alpha subunit p180 N terminal DUF4363 PF14276.1 EPR77798.1 - 0.014 15.1 2.9 0.016 14.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) LIM_bind PF01803.11 EPR77798.1 - 0.033 13.2 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein A2L_zn_ribbon PF08792.5 EPR77798.1 - 0.08 12.4 5.6 2.2 7.8 0.4 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-A20 PF01754.11 EPR77798.1 - 8.9 5.9 8.3 12 5.5 0.9 2.3 2 0 0 2 2 2 0 A20-like zinc finger Chorismate_bind PF00425.13 EPR77800.1 - 0.017 14.4 0.8 0.069 12.4 0.5 1.8 1 1 0 1 1 1 0 chorismate binding enzyme Taeniidae_ag PF05596.6 EPR77800.1 - 0.021 14.6 0.7 0.68 9.7 0.1 2.4 2 0 0 2 2 2 0 Taeniidae antigen NdhM PF10664.4 EPR77800.1 - 0.028 14.3 0.2 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Poxvirus PF06227.7 EPR77800.1 - 0.059 12.9 6.4 0.092 12.2 4.4 1.4 1 1 0 1 1 1 0 dsDNA Poxvirus CZB PF13682.1 EPR77800.1 - 0.068 13.3 0.1 11 6.3 0.0 2.2 1 1 1 2 2 2 0 Chemoreceptor zinc-binding domain SWIB PF02201.13 EPR77800.1 - 0.99 9.1 4.4 3.9 7.2 0.0 3.1 1 1 1 3 3 3 0 SWIB/MDM2 domain Aldo_ket_red PF00248.16 EPR77801.1 - 1.2e-41 142.4 0.8 2.9e-41 141.1 0.6 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_2b PF00587.20 EPR77802.1 - 3e-30 105.0 1.1 3.5e-30 104.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPR77802.1 - 1.2e-07 31.6 23.9 1.3e-06 28.3 16.6 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EPR77802.1 - 0.46 10.0 12.2 0.39 10.3 6.9 1.9 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 EPR77802.1 - 9.2 5.8 14.7 5.7 6.5 5.6 2.6 1 1 1 2 2 2 0 Septum formation initiator Borrelia_REV PF03978.8 EPR77803.1 - 0.18 11.5 9.2 0.23 11.1 6.3 1.3 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein SecD_SecF PF02355.11 EPR77804.1 - 0.029 13.5 1.4 0.052 12.7 0.9 1.3 1 0 0 1 1 1 0 Protein export membrane protein CKAP2_C PF15297.1 EPR77804.1 - 0.14 10.9 5.1 0.21 10.3 3.6 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2457 PF10446.4 EPR77804.1 - 0.23 10.1 7.4 0.27 9.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.1 EPR77804.1 - 1.6 8.3 6.5 3.1 7.4 4.5 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 EPR77804.1 - 4.5 5.1 12.2 5.5 4.8 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein U6-snRNA_bdg PF10596.4 EPR77805.1 - 1.6e-30 105.5 0.7 3.2e-30 104.6 0.5 1.4 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 LRR_8 PF13855.1 EPR77806.1 - 2.7e-06 27.0 16.0 0.00011 21.8 3.4 3.9 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EPR77806.1 - 0.00015 21.2 9.1 0.00064 19.2 0.5 5.8 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77806.1 - 0.0022 17.7 30.2 0.5 10.5 0.3 7.1 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR77806.1 - 6.6 7.4 18.5 29 5.4 0.1 6.0 5 0 0 5 5 5 0 Leucine rich repeat DDE_Tnp_IS1595 PF12762.2 EPR77807.1 - 7.1e-11 42.1 0.0 8.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_3 PF13358.1 EPR77808.1 - 1.8e-11 43.9 0.0 6.3e-11 42.2 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease MULE PF10551.4 EPR77809.1 - 3.6e-11 43.0 0.2 1.2e-08 34.9 0.0 2.5 2 1 0 2 2 2 2 MULE transposase domain Transposase_mut PF00872.13 EPR77809.1 - 0.00064 18.3 0.1 0.0011 17.5 0.1 1.7 1 1 0 1 1 1 1 Transposase, Mutator family FLYWCH PF04500.11 EPR77810.1 - 1.6e-11 43.8 0.8 2.7e-11 43.1 0.5 1.3 1 0 0 1 1 1 1 FLYWCH zinc finger domain DUF2481 PF10654.4 EPR77810.1 - 0.098 12.3 0.1 0.098 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) DDE_3 PF13358.1 EPR77811.1 - 1.8e-18 66.6 0.1 2e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EPR77811.1 - 5.2e-05 22.4 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EPR77811.1 - 0.027 14.5 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Extensin-like_C PF06904.7 EPR77812.1 - 0.011 15.4 0.1 5.5 6.7 0.0 2.4 3 0 0 3 3 3 0 Extensin-like protein C-terminus Pab87_oct PF13969.1 EPR77812.1 - 0.027 14.5 0.3 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 Pab87 octamerisation domain DUF1357 PF07094.6 EPR77812.1 - 0.071 12.5 2.3 2.1 7.7 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1357) CGI-121 PF08617.5 EPR77813.1 - 0.0053 16.4 2.9 0.0067 16.1 1.9 1.3 1 1 0 1 1 1 1 Kinase binding protein CGI-121 CCDC14 PF15254.1 EPR77813.1 - 0.017 13.5 5.7 0.022 13.1 3.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DUF3481 PF11980.3 EPR77814.1 - 0.019 14.7 0.7 0.036 13.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Ricin_B_lectin PF00652.17 EPR77817.1 - 0.0024 17.9 0.7 0.0024 17.9 0.5 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain BLOC1_2 PF10046.4 EPR77818.1 - 0.0021 18.1 17.4 0.019 15.0 5.2 2.2 1 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2730 PF10805.3 EPR77818.1 - 0.051 13.3 3.2 0.041 13.6 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) RRF_GI PF12614.3 EPR77818.1 - 0.077 12.8 2.4 0.13 12.1 1.4 1.6 1 1 0 1 1 1 0 Ribosome recycling factor DUF3828 PF12883.2 EPR77818.1 - 0.11 12.4 3.0 0.069 13.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3828) DUF745 PF05335.8 EPR77818.1 - 0.12 11.8 2.9 0.15 11.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Erf4 PF10256.4 EPR77818.1 - 0.15 11.9 4.3 0.18 11.6 2.6 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family BMFP PF04380.8 EPR77818.1 - 0.26 11.4 2.6 0.47 10.6 1.1 1.8 1 1 0 1 1 1 0 Membrane fusogenic activity DHquinase_II PF01220.14 EPR77818.1 - 0.32 10.3 2.3 3.3 7.0 0.1 2.2 1 1 1 2 2 2 0 Dehydroquinase class II YolD PF08863.5 EPR77818.1 - 1.5 8.7 11.6 0.22 11.3 4.6 2.0 1 1 1 2 2 2 0 YolD-like protein Fib_alpha PF08702.5 EPR77818.1 - 2.7 8.1 13.3 4.2 7.4 9.2 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 EPR77818.1 - 6.4 6.4 8.2 1.2 8.7 2.1 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 EPR77818.1 - 9 5.8 7.7 20 4.6 5.3 1.7 1 1 0 1 1 1 0 IncA protein CLAMP PF14769.1 EPR77819.1 - 0.084 13.0 2.4 0.2 11.7 1.7 1.6 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 tRNA_anti-codon PF01336.20 EPR77821.1 - 1.8e-06 27.7 0.1 6.2e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Mtp PF03821.11 EPR77823.1 - 2.5 7.4 10.7 0.084 12.2 2.6 1.8 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter Vma12 PF11712.3 EPR77823.1 - 2.6 7.7 13.0 0.72 9.5 0.3 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Zn_ribbon_recom PF13408.1 EPR77823.1 - 5 7.4 8.1 12 6.2 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2956 PF11169.3 EPR77824.1 - 2.1 8.3 10.6 13 5.8 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF4512 PF14975.1 EPR77824.1 - 5.1 7.9 8.1 7.6 7.4 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Mei5 PF10376.4 EPR77826.1 - 0.00037 20.0 1.9 0.00042 19.8 1.3 1.2 1 0 0 1 1 1 1 Double-strand recombination repair protein Octopine_DH PF02317.12 EPR77826.1 - 0.029 14.0 0.2 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Laminin_II PF06009.7 EPR77826.1 - 0.13 11.9 0.4 0.2 11.4 0.3 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF4249 PF14054.1 EPR77826.1 - 1 8.6 5.0 1.2 8.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Ribosomal_L29 PF00831.18 EPR77827.1 - 8.7e-12 44.5 5.0 1.1e-11 44.2 3.5 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein Pox_VLTF3 PF04947.9 EPR77827.1 - 0.25 10.8 2.5 0.26 10.7 1.7 1.0 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like DUF1456 PF07308.8 EPR77828.1 - 0.0026 17.7 2.0 4.4 7.4 0.0 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF1456) Band_3_cyto PF07565.8 EPR77829.1 - 6.4 6.1 7.0 0.52 9.7 1.7 1.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain UQ_con PF00179.21 EPR77832.1 - 9.1e-48 161.2 0.0 1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPR77832.1 - 2.4e-09 37.0 0.0 2.9e-09 36.7 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPR77832.1 - 0.00061 19.6 0.0 0.00071 19.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain SAC3_GANP PF03399.11 EPR77833.1 - 1.5e-05 24.6 2.0 1.7e-05 24.5 1.4 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPR77833.1 - 0.00054 19.7 1.1 0.0013 18.5 0.1 1.9 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TRAM_LAG1_CLN8 PF03798.11 EPR77836.1 - 1.5e-30 106.2 20.3 1.6e-30 106.1 14.1 1.0 1 0 0 1 1 1 1 TLC domain DUF2427 PF10348.4 EPR77836.1 - 2 8.0 10.5 1.2 8.6 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) Bromodomain PF00439.20 EPR77838.1 - 4.4e-18 64.9 4.5 1.1e-17 63.6 2.0 2.1 1 1 1 2 2 2 1 Bromodomain Fer4_12 PF13353.1 EPR77841.1 - 0.16 12.0 6.5 0.086 12.9 0.8 2.6 2 2 0 2 2 2 0 4Fe-4S single cluster domain NusA_N PF08529.6 EPR77841.1 - 0.44 10.5 6.9 0.12 12.4 1.5 2.2 1 1 1 2 2 2 0 NusA N-terminal domain Sec66 PF09802.4 EPR77842.1 - 0.72 9.2 7.4 0.92 8.8 4.0 2.1 1 1 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF1104 PF06518.6 EPR77842.1 - 5.8 7.1 18.8 2.4e+03 -1.3 13.1 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) Ndc1_Nup PF09531.5 EPR77842.1 - 6.4 5.0 14.0 7.7 4.7 9.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TES PF08034.6 EPR77843.1 - 3.4 7.8 13.8 0.43 10.6 1.8 2.6 1 1 1 2 2 2 0 Trematode eggshell synthesis protein DDE_Tnp_IS1595 PF12762.2 EPR77844.1 - 0.00078 19.3 0.0 0.00097 18.9 0.0 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain LRR_4 PF12799.2 EPR77846.1 - 1.8e-23 81.6 66.2 8e-07 28.5 1.8 8.3 5 3 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77846.1 - 6.4e-23 80.2 75.9 4.5e-08 32.7 4.1 6.0 4 1 3 7 7 7 7 Leucine rich repeat LRR_7 PF13504.1 EPR77846.1 - 5e-11 40.9 30.7 1.1 9.7 0.1 11.5 11 0 0 11 11 11 5 Leucine rich repeat LRR_1 PF00560.28 EPR77846.1 - 6e-09 34.7 56.6 0.042 13.8 0.4 12.6 13 1 0 13 13 13 7 Leucine Rich Repeat LRR_6 PF13516.1 EPR77846.1 - 0.2 11.8 54.9 0.62 10.2 0.6 11.0 12 1 0 12 12 12 0 Leucine Rich repeat LRR_8 PF13855.1 EPR77849.1 - 3.9e-14 52.1 22.1 3.6e-08 33.0 2.9 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EPR77849.1 - 8.2e-08 31.6 17.8 0.00053 19.5 1.1 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77849.1 - 5.8e-07 28.6 13.0 0.22 11.6 0.3 4.8 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR77849.1 - 0.0078 16.2 8.8 15 6.3 0.0 5.0 4 1 1 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EPR77849.1 - 0.014 15.4 12.8 0.15 12.1 0.1 4.5 3 1 1 4 4 4 0 Leucine Rich repeat Glyco_transf_8 PF01501.15 EPR77849.1 - 0.13 11.6 2.1 0.16 11.2 1.5 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 DDE_Tnp_IS1595 PF12762.2 EPR77850.1 - 8.3e-05 22.4 0.0 0.0001 22.2 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain bZIP_1 PF00170.16 EPR77852.1 - 6.9e-08 32.3 8.3 1.5e-07 31.2 5.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPR77852.1 - 9.6e-05 22.1 6.5 0.00024 20.8 4.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPR77852.1 - 0.0019 18.4 1.8 0.003 17.7 1.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Med24_N PF11277.3 EPR77852.1 - 0.021 12.3 0.2 0.023 12.2 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Tbf5 PF06331.7 EPR77852.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Antigen_Bd37 PF11641.3 EPR77852.1 - 0.42 9.8 5.2 1.4 8.1 2.1 2.1 1 1 0 2 2 2 0 Glycosylphosphatidylinositol-anchored merozoite surface protein zf-trcl PF13451.1 EPR77853.1 - 0.12 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Probable zinc-binding domain DUF947 PF06102.7 EPR77854.1 - 0.0017 18.2 10.0 0.23 11.2 0.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF947) DUF2969 PF11184.3 EPR77854.1 - 0.26 11.4 0.2 0.26 11.4 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2969) YgbA_NO PF11756.3 EPR77855.1 - 0.15 12.1 1.6 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter Utp11 PF03998.8 EPR77857.1 - 0.082 12.7 1.2 0.099 12.4 0.8 1.1 1 0 0 1 1 1 0 Utp11 protein DUF2415 PF10313.4 EPR77858.1 - 6.3e-08 32.1 0.0 4.5e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) XPG_I PF00867.13 EPR77858.1 - 0.062 13.3 0.3 0.69 10.0 0.2 2.8 1 0 0 1 1 1 0 XPG I-region Sugar_tr PF00083.19 EPR77859.1 - 1.7e-40 138.9 45.2 4.7e-24 84.7 14.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPR77859.1 - 4e-09 35.6 62.0 6.8e-08 31.6 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TK PF00265.13 EPR77860.1 - 4.1e-35 120.9 0.5 4.7e-35 120.7 0.4 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_22 PF13401.1 EPR77860.1 - 0.0083 16.2 0.7 0.022 14.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain Ycf54 PF10674.4 EPR77860.1 - 0.051 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2488) MCM PF00493.18 EPR77863.1 - 8.3e-122 406.1 3.0 1.3e-121 405.4 2.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPR77863.1 - 1.3e-13 51.5 1.0 3.8e-13 49.9 0.7 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPR77863.1 - 9.9e-08 31.3 0.1 1.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPR77863.1 - 0.00039 20.1 0.1 0.0021 17.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ECIST_Cterm PF14784.1 EPR77864.1 - 1.4 8.9 6.7 0.18 11.7 0.6 2.3 2 1 0 2 2 2 0 C-terminal domain of the ECSIT protein IF2_N PF04760.10 EPR77864.1 - 2.7 7.7 6.1 5.8 6.6 0.1 3.4 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region Proteasome PF00227.21 EPR77867.1 - 1.1e-14 54.1 0.7 3.6e-05 23.1 0.0 3.1 2 1 1 3 3 3 3 Proteasome subunit KilA-N PF04383.8 EPR77868.1 - 0.27 10.8 7.0 0.049 13.2 2.2 1.7 2 1 0 2 2 2 0 KilA-N domain zf-HC5HC2H PF13771.1 EPR77869.1 - 0.39 10.8 5.6 6.2 7.0 0.0 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain Pkinase PF00069.20 EPR77870.1 - 2.7e-08 33.3 3.9 2.3e-06 26.9 2.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR77870.1 - 3.4e-05 23.0 1.1 0.0039 16.3 0.7 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase GvpH PF05455.6 EPR77871.1 - 0.1 12.2 1.8 0.12 11.9 1.2 1.1 1 0 0 1 1 1 0 GvpH Pkinase PF00069.20 EPR77872.1 - 2.7e-37 128.3 3.4 2e-21 76.3 1.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPR77872.1 - 3.3e-21 75.5 0.5 1e-15 57.5 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPR77872.1 - 0.0013 17.7 0.0 0.023 13.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPR77872.1 - 0.029 14.1 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.2 EPR77873.1 - 2.5e-15 55.6 5.0 3.5e-08 32.8 0.1 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77873.1 - 2.5e-11 43.1 9.8 9.4e-10 38.1 0.2 3.5 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR77873.1 - 1.1e-06 27.8 14.8 0.019 14.9 0.1 5.5 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EPR77873.1 - 7.2e-05 22.3 5.0 7.1 7.3 0.0 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EPR77873.1 - 0.00078 19.2 7.2 1.9 8.8 0.0 5.0 4 1 0 4 4 4 1 Leucine Rich repeat EF-hand_6 PF13405.1 EPR77874.1 - 1.1e-08 34.2 0.3 0.012 15.4 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EPR77874.1 - 1.1e-08 33.7 1.3 0.0036 16.5 0.0 3.9 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.1 EPR77874.1 - 6.6e-05 22.9 0.5 0.042 13.9 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPR77874.1 - 9.1e-05 21.9 0.2 0.052 13.1 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair WXG100 PF06013.7 EPR77874.1 - 0.13 12.3 0.1 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF1642 PF07852.6 EPR77874.1 - 0.18 12.1 2.5 0.24 11.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) ComK PF06338.6 EPR77875.1 - 0.0037 16.7 2.5 0.0057 16.1 1.7 1.3 1 0 0 1 1 1 1 ComK protein Rota_NSP4 PF01452.11 EPR77875.1 - 0.027 13.8 4.0 0.034 13.4 2.8 1.1 1 0 0 1 1 1 0 Rotavirus non structural protein DUF3596 PF12167.3 EPR77877.1 - 0.064 12.8 0.1 0.26 10.8 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) KaiA PF07688.7 EPR77878.1 - 0.073 12.3 0.4 0.1 11.8 0.3 1.2 1 0 0 1 1 1 0 KaiA domain Cyclin_N PF00134.18 EPR77879.1 - 1.4e-32 111.9 1.8 1.1e-29 102.6 0.4 2.8 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPR77879.1 - 5.7e-14 52.0 0.1 1.4e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4408 PF14364.1 EPR77879.1 - 0.065 12.8 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4408) DUF940 PF06082.6 EPR77879.1 - 0.95 7.9 8.4 0.027 13.0 1.2 1.7 2 0 0 2 2 2 0 Bacterial putative lipoprotein (DUF940) DUF3269 PF11673.3 EPR77880.1 - 0.68 10.4 9.2 3.8 8.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3269) Sigma70_r1_1 PF03979.9 EPR77881.1 - 0.0064 16.3 1.4 2 8.4 0.1 2.8 2 0 0 2 2 2 2 Sigma-70 factor, region 1.1 Nebulin PF00880.13 EPR77881.1 - 0.058 13.0 0.3 0.058 13.0 0.2 2.6 2 0 0 2 2 2 0 Nebulin repeat Ras PF00071.17 EPR77881.1 - 0.48 9.7 5.3 43 3.4 3.6 2.3 1 1 0 1 1 1 0 Ras family CLTH PF10607.4 EPR77881.1 - 8.2 6.1 28.1 6.4 6.4 17.2 2.3 2 1 0 2 2 2 0 CTLH/CRA C-terminal to LisH motif domain LRR_8 PF13855.1 EPR77882.1 - 4.3e-21 74.4 35.7 1.1e-06 28.3 4.6 7.8 6 2 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EPR77882.1 - 5.3e-18 64.2 48.8 1.7e-08 33.9 6.4 8.8 7 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77882.1 - 3.2e-09 35.5 25.5 0.035 14.1 0.1 8.3 6 2 1 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR77882.1 - 8.5e-06 25.1 9.4 11 6.7 0.0 8.6 9 0 0 9 9 9 2 Leucine rich repeat LRR_9 PF14580.1 EPR77882.1 - 0.0079 15.7 16.7 0.047 13.2 1.1 3.4 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 EPR77882.1 - 0.028 14.4 32.0 0.59 10.3 0.6 9.8 12 1 0 12 12 12 0 Leucine Rich repeat PRTP PF01366.13 EPR77883.1 - 0.0021 16.1 0.2 0.0026 15.8 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus processing and transport protein 5_3_exonuc PF01367.15 EPR77884.1 - 1.9 8.7 6.8 20 5.5 0.1 3.5 3 1 1 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold DUF4612 PF15389.1 EPR77884.1 - 7.4 7.2 9.0 3.3 8.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4612) HeH PF12949.2 EPR77886.1 - 2.9e-05 23.5 0.3 5.8e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 HeH/LEM domain PMC2NT PF08066.7 EPR77887.1 - 7.7 6.9 6.7 0.66 10.3 1.0 2.1 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Pkinase PF00069.20 EPR77892.1 - 4.1e-65 219.5 0.2 8.3e-65 218.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR77892.1 - 6.1e-32 110.7 0.0 9.2e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR77892.1 - 1.7e-06 27.2 0.0 3.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPR77892.1 - 5.1e-05 22.4 0.0 0.00013 21.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR77892.1 - 0.00079 19.2 0.0 0.0023 17.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family 14-3-3 PF00244.15 EPR77894.1 - 1.8e-86 289.0 7.6 2.3e-86 288.7 5.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF2580 PF10824.3 EPR77894.1 - 0.13 12.6 0.4 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) DUF2762 PF10960.3 EPR77894.1 - 1.7 8.4 5.7 26 4.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) ABC_tran PF00005.22 EPR77895.1 - 4.9e-12 46.3 0.1 8.3e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF2813 PF11398.3 EPR77895.1 - 0.0009 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) DUF815 PF05673.8 EPR77895.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 EPR77895.1 - 0.03 14.8 0.1 0.083 13.3 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EPR77895.1 - 0.034 14.1 1.0 0.047 13.6 0.2 1.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPR77895.1 - 0.1 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.1 EPR77895.1 - 0.14 11.7 0.1 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1565 PF07602.6 EPR77895.1 - 7.4 5.6 8.4 6.1 5.9 1.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1565) DUF694 PF05107.7 EPR77897.1 - 0.0052 16.0 2.8 0.0095 15.1 1.3 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF694) PUF PF00806.14 EPR77897.1 - 0.036 13.5 0.3 10 5.8 0.0 2.8 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat DUF4064 PF13273.1 EPR77899.1 - 2.5 8.2 7.7 3.6 7.7 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Tic20 PF09685.5 EPR77899.1 - 2.7 8.0 8.7 4.3 7.3 6.0 1.4 1 1 0 1 1 1 0 Tic20-like protein RhoGAP PF00620.22 EPR77900.1 - 1.7e-14 53.6 0.2 2.6e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain 2OG-Fe_Oxy_2 PF10014.4 EPR77900.1 - 0.022 14.1 0.2 0.035 13.4 0.2 1.2 1 0 0 1 1 1 0 2OG-Fe dioxygenase MutS_V PF00488.16 EPR77901.1 - 1.3e-35 122.9 0.2 2e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPR77901.1 - 4.7e-05 23.2 0.4 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EPR77901.1 - 0.00012 22.2 1.0 0.00012 22.2 0.7 2.1 2 0 0 2 2 2 1 MutS family domain IV AAA_29 PF13555.1 EPR77901.1 - 0.00078 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EPR77901.1 - 0.0025 17.7 0.6 0.0025 17.7 0.4 2.8 2 2 1 3 3 3 1 AAA domain NTPase_1 PF03266.10 EPR77901.1 - 0.028 14.1 2.6 1.3 8.6 0.1 3.1 4 0 0 4 4 4 0 NTPase ABC_tran PF00005.22 EPR77901.1 - 0.031 14.5 2.7 0.097 12.9 1.9 2.0 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 EPR77901.1 - 0.038 14.1 0.3 0.095 12.9 0.2 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EPR77901.1 - 0.04 12.8 0.1 0.076 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 EPR77901.1 - 0.13 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EPR77901.1 - 0.49 9.5 2.6 0.41 9.8 0.2 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPR77901.1 - 1.2 9.9 7.1 1 10.2 0.1 3.4 2 2 0 2 2 2 0 AAA domain Pkinase PF00069.20 EPR77902.1 - 1.6e-50 171.6 2.6 2.1e-50 171.2 1.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR77902.1 - 1.9e-22 79.6 0.2 2.8e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPR77902.1 - 0.032 13.9 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MutS_III PF05192.13 EPR77903.1 - 1.2e-08 34.9 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MitMem_reg PF13012.1 EPR77904.1 - 0.22 11.6 6.9 0.07 13.2 1.0 2.1 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function PIN_2 PF10130.4 EPR77904.1 - 0.34 10.9 3.0 0.78 9.7 2.1 1.6 1 1 0 1 1 1 0 PIN domain RabGAP-TBC PF00566.13 EPR77904.1 - 1.3 8.4 5.5 1.6 8.1 3.6 1.3 1 1 0 1 1 1 0 Rab-GTPase-TBC domain ATG16 PF08614.6 EPR77904.1 - 1.6 8.4 6.6 1.1 9.0 3.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RE_AlwI PF09491.5 EPR77904.1 - 1.8 6.9 17.4 2.1 6.7 12.0 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease Mitofilin PF09731.4 EPR77904.1 - 2.2 6.8 7.8 2.6 6.6 5.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cu_bind_like PF02298.12 EPR77905.1 - 1.4 8.7 6.2 5.6 6.8 4.3 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Eaf7 PF07904.8 EPR77906.1 - 1.8e-06 27.8 1.4 3.9e-06 26.7 1.0 1.5 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 WIYLD PF10440.4 EPR77906.1 - 0.026 14.4 1.2 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-binding WIYLD domain UAA PF08449.6 EPR77907.1 - 7.8e-49 166.2 40.9 9.7e-49 165.9 28.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPR77907.1 - 5.4e-06 26.4 14.3 5.4e-06 26.4 9.9 3.5 3 1 1 4 4 4 1 EamA-like transporter family TPT PF03151.11 EPR77907.1 - 0.00045 19.8 16.4 0.00045 19.8 11.4 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EPR77907.1 - 3.3 7.9 38.5 0.3 11.3 8.8 3.3 3 1 1 4 4 4 0 Multidrug resistance efflux transporter LRR_4 PF12799.2 EPR77910.1 - 1.1e-15 56.8 25.0 2.8e-05 23.6 0.1 4.7 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77910.1 - 1.4e-09 37.5 24.3 1.5e-06 27.8 1.1 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR77910.1 - 9.3e-08 31.0 19.3 0.015 15.2 2.0 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR77910.1 - 7.4e-06 25.3 11.0 1.1 9.8 0.8 5.8 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EPR77910.1 - 3.8e-05 23.3 19.5 0.043 13.8 2.6 5.5 4 1 1 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.1 EPR77910.1 - 0.0032 17.0 5.6 0.0079 15.7 1.4 2.1 1 1 0 2 2 2 1 Leucine-rich repeat LRR_2 PF07723.8 EPR77910.1 - 1.1 9.9 3.7 1e+02 3.6 0.0 4.3 3 1 1 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.2 EPR77911.1 - 7.5e-05 22.2 18.8 0.0023 17.4 2.3 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77911.1 - 0.0015 18.2 19.6 0.14 12.2 0.5 4.3 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EPR77911.1 - 0.0038 17.1 9.9 3.5 8.2 0.1 4.4 3 1 1 4 4 4 2 Leucine rich repeat LRR_8 PF13855.1 EPR77911.1 - 0.052 13.3 12.9 1.9 8.2 4.8 2.9 2 1 0 2 2 2 0 Leucine rich repeat CBFD_NFYB_HMF PF00808.18 EPR77912.1 - 6.9e-05 22.8 0.7 0.00013 21.9 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR77912.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4258 PF14076.1 EPR77912.1 - 0.17 11.9 3.9 3 7.9 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4258) HTH_Tnp_Tc3_2 PF01498.13 EPR77913.1 - 0.0077 16.2 0.2 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Transposase Laminin_I PF06008.9 EPR77913.1 - 0.085 12.1 0.2 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain I HTH_32 PF13565.1 EPR77913.1 - 0.11 13.3 0.1 0.16 12.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain tRNA_m1G_MT PF01746.16 EPR77914.1 - 2.9e-22 79.1 1.0 8.6e-22 77.6 0.7 1.7 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Metallophos_2 PF12850.2 EPR77914.1 - 0.033 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glt_symporter PF03616.9 EPR77914.1 - 0.14 10.6 1.0 0.17 10.3 0.7 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter AMP-binding PF00501.23 EPR77915.1 - 1.5e-48 165.2 0.0 1.8e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme YopX PF09643.5 EPR77915.1 - 1.3 8.9 5.0 2.6 8.0 1.9 2.2 1 1 1 2 2 2 0 YopX protein tRNA-synt_2 PF00152.15 EPR77916.1 - 8.3e-91 304.2 2.2 1.2e-90 303.6 1.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPR77916.1 - 3.1e-12 46.1 1.1 8.5e-12 44.7 0.7 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPR77916.1 - 3.7e-08 32.8 0.1 0.00032 19.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPR77916.1 - 0.01 15.4 0.6 0.29 10.6 0.4 2.6 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) TFIIS_M PF07500.9 EPR77916.1 - 1.8 8.6 6.9 11 6.0 0.0 3.4 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS), central domain Prenyltransf PF01255.14 EPR77917.1 - 5.5e-24 84.5 7.5 5.5e-14 51.8 0.0 4.0 2 1 1 3 3 3 3 Putative undecaprenyl diphosphate synthase DUF912 PF06024.7 EPR77917.1 - 0.089 12.8 1.5 0.17 11.9 1.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mucin PF01456.12 EPR77917.1 - 0.4 10.4 9.8 0.59 9.9 6.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Pap_E4 PF02711.9 EPR77917.1 - 5 8.0 6.7 8 7.3 4.7 1.2 1 0 0 1 1 1 0 E4 protein ThiF PF00899.16 EPR77918.1 - 1.6e-38 131.5 0.7 2.6e-38 130.9 0.1 1.7 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EPR77918.1 - 6e-23 80.2 0.2 9.7e-23 79.5 0.1 1.3 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EPR77918.1 - 3e-07 30.7 0.0 5.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF3388 PF11868.3 EPR77918.1 - 0.0061 15.7 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) UDPG_MGDP_dh_N PF03721.9 EPR77918.1 - 0.065 12.6 0.6 0.18 11.2 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RRF_GI PF12614.3 EPR77919.1 - 2.6 7.8 7.2 0.61 9.9 0.1 3.0 3 0 0 3 3 3 0 Ribosome recycling factor DENN PF02141.16 EPR77920.1 - 3.2e-10 40.0 0.4 1.5e-09 37.8 0.0 2.3 3 0 0 3 3 3 1 DENN (AEX-3) domain Tfb2 PF03849.9 EPR77921.1 - 1.8e-41 141.9 9.4 5.8e-39 133.7 6.5 3.0 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EPR77921.1 - 1.4e-07 31.3 0.0 3.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Arf PF00025.16 EPR77922.1 - 1.4e-16 60.2 0.1 2.2e-16 59.6 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPR77922.1 - 0.025 15.0 0.0 0.051 14.0 0.0 1.5 2 0 0 2 2 2 0 Miro-like protein Ribosomal_S7 PF00177.16 EPR77922.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e DUF3550 PF12070.3 EPR77922.1 - 0.12 11.1 0.1 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) RNA_pol_A_bac PF01000.21 EPR77923.1 - 1.1e-19 70.6 2.1 1.3e-19 70.3 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPR77923.1 - 1.7e-12 46.2 0.1 2.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2407 PF10302.4 EPR77924.1 - 0.0051 16.9 0.3 0.019 15.1 0.2 2.1 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain TBPIP PF07106.8 EPR77924.1 - 0.03 13.8 10.5 0.046 13.2 7.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlxA PF14282.1 EPR77924.1 - 0.13 12.2 7.3 0.23 11.3 5.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Lge1 PF11488.3 EPR77924.1 - 0.2 11.8 2.7 0.68 10.1 1.8 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF1664 PF07889.7 EPR77924.1 - 0.36 10.6 4.3 0.79 9.5 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EPR77924.1 - 0.58 9.6 11.2 1.2 8.6 3.3 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4315 PF14193.1 EPR77924.1 - 0.72 9.8 14.3 0.33 10.9 8.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) IATP PF04568.7 EPR77924.1 - 3.9 7.5 6.6 1.5 8.9 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF1796 PF08795.5 EPR77925.1 - 0.064 12.8 4.7 0.084 12.4 2.0 1.9 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Glu_syn_central PF04898.9 EPR77925.1 - 0.14 11.4 7.3 0.038 13.2 1.3 1.9 1 1 1 2 2 2 0 Glutamate synthase central domain DUF848 PF05852.6 EPR77925.1 - 1.1 9.0 6.0 2.3 8.0 1.0 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Med3 PF11593.3 EPR77925.1 - 4.8 6.3 13.2 0.038 13.2 2.1 2.2 2 1 0 2 2 2 0 Mediator complex subunit 3 fungal UCH PF00443.24 EPR77926.1 - 1.6e-23 83.1 5.2 2e-23 82.8 3.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR77926.1 - 7.7e-07 28.8 2.1 3.5e-05 23.4 1.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase XisI PF08869.6 EPR77926.1 - 1.4 9.0 4.8 0.32 11.1 0.3 2.2 3 0 0 3 3 3 0 XisI protein SID-1_RNA_chan PF13965.1 EPR77927.1 - 0.00063 18.0 2.3 0.0007 17.8 1.6 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 CDC45 PF02724.9 EPR77927.1 - 0.019 13.0 1.4 0.022 12.8 1.0 1.0 1 0 0 1 1 1 0 CDC45-like protein TMEM154 PF15102.1 EPR77927.1 - 0.083 12.6 2.9 0.22 11.2 2.0 1.8 1 1 0 1 1 1 0 TMEM154 protein family Myc_target_1 PF15179.1 EPR77927.1 - 0.22 11.0 1.1 0.4 10.2 0.8 1.6 1 1 0 1 1 1 0 Myc target protein 1 Tmemb_9 PF05434.6 EPR77927.1 - 0.35 10.6 3.3 1.6 8.4 2.3 1.9 1 1 0 1 1 1 0 TMEM9 Rax2 PF12768.2 EPR77927.1 - 1.1 8.3 7.9 0.14 11.3 1.0 2.0 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Casein PF00363.13 EPR77929.1 - 0.045 14.3 0.5 0.078 13.6 0.3 1.5 1 1 0 1 1 1 0 Casein MCM_N PF14551.1 EPR77929.1 - 0.85 10.1 6.6 3.8 8.0 3.9 2.3 1 1 1 2 2 2 0 MCM N-terminal domain GPCR_chapero_1 PF11904.3 EPR77930.1 - 0.028 13.5 1.1 0.042 12.9 0.8 1.2 1 0 0 1 1 1 0 GPCR-chaperone BRX_N PF13713.1 EPR77930.1 - 0.072 12.5 0.2 0.16 11.4 0.2 1.5 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Glucosamine_iso PF01182.15 EPR77931.1 - 2.6e-23 82.8 0.0 6.6e-23 81.4 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sugar-bind PF04198.8 EPR77931.1 - 0.046 12.6 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain DUF3546 PF12066.3 EPR77932.1 - 2.9e-05 24.0 4.1 2.9e-05 24.0 2.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EPR77932.1 - 0.0002 21.6 1.5 0.00058 20.1 1.1 1.8 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EPR77932.1 - 0.0023 17.5 4.3 0.0023 17.5 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 EPR77932.1 - 0.72 10.0 9.6 0.39 10.8 3.0 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) LUC7 PF03194.10 EPR77933.1 - 2.2e-20 73.2 9.8 3e-20 72.8 6.8 1.2 1 0 0 1 1 1 1 LUC7 N_terminus zf-C2H2_jaz PF12171.3 EPR77933.1 - 0.019 15.0 0.5 3 8.0 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribosomal_L28e PF01778.12 EPR77934.1 - 9.5e-24 84.0 0.1 9.5e-24 84.0 0.1 2.3 2 1 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EPR77934.1 - 0.0053 16.8 8.3 0.0053 16.8 5.8 1.9 2 0 0 2 2 2 1 Mak16 protein C-terminal region DUF1106 PF06523.6 EPR77935.1 - 0.005 16.6 3.5 0.011 15.5 2.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1106) L_biotic_typeA PF04604.8 EPR77936.1 - 0.095 12.3 0.1 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Type-A lantibiotic Fijivirus_P9-2 PF06837.6 EPR77936.1 - 1.8 7.6 12.6 2.1 7.4 8.7 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein Grp1_Fun34_YaaH PF01184.14 EPR77936.1 - 1.8 7.8 6.0 2.1 7.5 4.2 1.0 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Nop PF01798.13 EPR77937.1 - 8.6e-09 34.8 2.4 3.2e-08 33.0 0.1 2.3 1 1 1 2 2 2 1 Putative snoRNA binding domain DIX PF00778.12 EPR77937.1 - 0.06 13.0 0.9 0.06 13.0 0.6 2.9 2 1 1 3 3 3 0 DIX domain GTP-bdg_N PF13167.1 EPR77937.1 - 0.58 10.3 11.3 0.14 12.2 3.5 2.6 2 1 1 3 3 3 0 GTP-binding GTPase N-terminal Cpn60_TCP1 PF00118.19 EPR77939.1 - 2e-120 402.6 12.3 2.3e-120 402.4 8.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tcp10_C PF07202.8 EPR77940.1 - 9.7e-06 25.2 0.7 0.00015 21.3 0.0 1.9 1 1 1 2 2 2 1 T-complex protein 10 C-terminus WD40_alt PF14077.1 EPR77940.1 - 0.37 10.4 2.4 10 5.8 0.8 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif Ssl1 PF04056.9 EPR77941.1 - 0.0021 17.6 0.1 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EPR77941.1 - 0.014 15.4 0.0 0.018 15.1 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain CSD PF00313.17 EPR77942.1 - 1.5e-15 56.6 0.3 2.7e-15 55.8 0.2 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EPR77942.1 - 0.03 13.8 1.0 0.084 12.3 0.7 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Cuticle_1 PF08140.6 EPR77942.1 - 0.055 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Pkinase PF00069.20 EPR77943.1 - 1.3e-69 234.2 0.0 1.4e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR77943.1 - 2.6e-33 115.2 0.0 3.5e-33 114.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR77943.1 - 1.1e-06 27.8 0.0 3e-06 26.3 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EPR77943.1 - 0.0002 20.4 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPR77943.1 - 0.0047 15.8 0.0 0.0083 14.9 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EPR77943.1 - 0.0091 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPR77943.1 - 1.7 7.3 5.8 0.93 8.2 0.1 2.7 1 1 1 3 3 3 0 Poxvirus serine/threonine protein kinase Ribosomal_L23 PF00276.15 EPR77944.1 - 7.4e-11 41.8 0.8 7.4e-11 41.8 0.5 2.0 2 1 0 2 2 2 1 Ribosomal protein L23 5_3_exonuc PF01367.15 EPR77944.1 - 0.047 13.9 0.2 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF747 PF05346.6 EPR77945.1 - 3.7e-42 144.5 24.0 3.7e-42 144.5 16.6 2.0 1 1 1 2 2 2 2 Eukaryotic membrane protein family Sulfate_transp PF00916.15 EPR77946.1 - 4.1e-14 52.2 13.4 4.1e-14 52.2 9.3 2.8 2 1 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 EPR77946.1 - 0.027 13.8 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.15 EPR77947.1 - 3.9e-11 42.4 10.4 3.9e-11 42.4 7.2 2.9 2 1 0 2 2 2 1 Sulfate transporter family Peptidase_M24 PF00557.19 EPR77948.1 - 1.5e-33 116.1 0.0 2.3e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPR77948.1 - 2.5e-14 53.9 0.2 1.1e-13 51.8 0.0 2.0 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain UCH PF00443.24 EPR77949.1 - 2.7e-27 95.5 58.6 2.7e-27 95.5 40.7 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR77949.1 - 5.3e-09 35.9 28.7 4.2e-07 29.6 19.9 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RhoGEF PF00621.15 EPR77950.1 - 4.3e-17 62.5 10.5 1.2e-16 61.0 7.3 1.9 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EPR77950.1 - 4.8e-15 55.7 1.8 1.5e-14 54.0 1.3 1.8 1 1 0 1 1 1 1 CNH domain DUF1312 PF07009.6 EPR77951.1 - 1.3 8.8 9.0 0.21 11.3 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1312) ABC_tran PF00005.22 EPR77952.1 - 9.8e-27 93.9 0.0 1.7e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPR77952.1 - 4.6e-11 43.2 14.7 7.8e-08 32.6 0.9 3.5 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.1 EPR77952.1 - 6.6e-06 25.4 8.8 0.0036 16.4 0.1 3.6 3 1 1 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 EPR77952.1 - 6.7e-05 22.2 0.5 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPR77952.1 - 0.00024 20.5 0.3 0.00062 19.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EPR77952.1 - 0.00034 20.0 0.0 0.0014 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR77952.1 - 0.00041 21.1 0.0 0.0011 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPR77952.1 - 0.00049 20.2 0.1 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPR77952.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPR77952.1 - 0.0013 19.0 0.0 0.0034 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EPR77952.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EPR77952.1 - 0.0056 15.8 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 EPR77952.1 - 0.0064 16.1 0.2 0.085 12.4 0.2 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPR77952.1 - 0.011 15.4 0.2 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 EPR77952.1 - 0.011 15.4 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EPR77952.1 - 0.011 15.6 0.1 0.32 10.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 EPR77952.1 - 0.012 15.0 0.3 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EPR77952.1 - 0.013 15.2 0.3 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EPR77952.1 - 0.016 14.8 0.1 0.046 13.4 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EPR77952.1 - 0.019 14.4 0.6 0.031 13.7 0.4 1.3 1 0 0 1 1 1 0 AAA-like domain PIF1 PF05970.9 EPR77952.1 - 0.023 13.6 0.4 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase MobB PF03205.9 EPR77952.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPR77952.1 - 0.045 13.6 0.2 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EPR77952.1 - 0.057 13.0 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arc_PepC_II PF06847.6 EPR77952.1 - 0.068 13.6 0.1 0.18 12.2 0.1 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II AAA_28 PF13521.1 EPR77952.1 - 0.071 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EPR77952.1 - 0.074 12.9 0.0 0.46 10.4 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EPR77952.1 - 0.081 13.2 7.1 0.1 12.8 2.7 2.5 2 1 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EPR77952.1 - 0.093 12.6 0.2 0.22 11.4 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EPR77952.1 - 0.095 11.5 1.0 0.13 11.0 0.2 1.5 2 0 0 2 2 1 0 NB-ARC domain PduV-EutP PF10662.4 EPR77952.1 - 0.1 12.0 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EPR77952.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 EPR77952.1 - 0.15 12.2 0.7 0.44 10.7 0.5 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EPR77952.1 - 0.15 11.5 0.2 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EPR77952.1 - 0.16 11.5 0.2 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EPR77952.1 - 0.67 9.7 6.1 1.8 8.3 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 Mg_chelatase PF01078.16 EPR77952.1 - 0.95 8.5 2.5 0.74 8.9 0.3 1.8 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Tn7_Tnp_TnsA_C PF08721.6 EPR77954.1 - 0.0059 16.6 2.7 1.6 8.7 0.1 2.6 2 0 0 2 2 2 2 TnsA endonuclease C terminal Mitofilin PF09731.4 EPR77954.1 - 0.011 14.3 0.3 0.011 14.3 0.2 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein DUF445 PF04286.7 EPR77954.1 - 0.048 13.1 2.8 0.069 12.6 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Crust_neurohorm PF01147.12 EPR77954.1 - 0.059 12.6 0.2 0.13 11.5 0.1 1.6 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Carbpep_Y_N PF05388.6 EPR77954.1 - 0.27 11.4 5.1 0.76 9.9 0.9 2.8 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide TryThrA_C PF12319.3 EPR77954.1 - 0.27 10.3 7.8 0.18 10.9 0.6 2.4 2 1 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal Sipho_tail PF05709.6 EPR77954.1 - 0.41 9.7 6.3 0.88 8.6 4.4 1.5 1 1 0 1 1 1 0 Phage tail protein DUF1548 PF07579.6 EPR77954.1 - 0.45 10.6 6.9 0.68 10.0 0.5 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) UPF0184 PF03670.8 EPR77954.1 - 1.8 8.7 5.8 7.7 6.7 0.1 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Flavodoxin_1 PF00258.20 EPR77955.1 - 6.9e-18 65.0 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Erf4 PF10256.4 EPR77957.1 - 0.068 13.0 0.2 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family LRR_8 PF13855.1 EPR77958.1 - 1.3e-12 47.2 20.8 3.9e-07 29.7 2.2 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EPR77958.1 - 4.2e-09 35.8 24.2 1.4e-05 24.5 0.4 4.1 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77958.1 - 4.4e-05 22.9 19.8 0.013 15.4 0.1 5.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR77958.1 - 0.0049 16.8 8.8 1.9 9.0 0.0 4.9 4 1 0 4 4 4 2 Leucine rich repeat UCH PF00443.24 EPR77958.1 - 0.12 11.4 1.6 0.24 10.4 1.1 1.5 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase ASL_C PF08328.6 EPR77958.1 - 0.14 11.9 1.0 7 6.5 0.0 3.0 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminal LRR_6 PF13516.1 EPR77958.1 - 0.44 10.7 0.1 0.44 10.7 0.0 5.1 6 1 1 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.2 EPR77959.1 - 2.2e-26 90.9 55.4 6e-07 28.9 1.1 8.0 4 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77959.1 - 1.4e-21 76.0 45.6 8.6e-08 31.8 2.3 6.3 3 2 3 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 EPR77959.1 - 6e-16 56.0 51.6 0.06 13.4 0.2 11.9 9 2 1 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR77959.1 - 1.1e-10 39.8 26.6 0.84 10.1 0.1 11.9 12 1 1 13 13 13 4 Leucine rich repeat LRR_6 PF13516.1 EPR77959.1 - 2e-07 30.3 47.2 0.054 13.5 0.2 11.5 13 0 0 13 13 13 4 Leucine Rich repeat LRR_2 PF07723.8 EPR77959.1 - 0.028 14.8 5.3 27 5.4 0.0 6.0 5 1 1 6 6 6 0 Leucine Rich Repeat Phage_DsbA PF11126.3 EPR77959.1 - 0.051 13.6 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator DsbA Raftlin PF15250.1 EPR77960.1 - 0.069 11.6 8.0 0.081 11.4 5.6 1.0 1 0 0 1 1 1 0 Raftlin Fibrinogen_BP PF08017.6 EPR77960.1 - 0.085 11.0 1.7 0.091 10.9 1.2 1.0 1 0 0 1 1 1 0 Fibrinogen binding protein Serinc PF03348.10 EPR77960.1 - 0.37 9.4 2.4 0.43 9.2 1.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) HTH_16 PF12645.2 EPR77960.1 - 0.4 10.6 7.1 2.8 7.9 0.1 3.3 1 1 2 3 3 3 0 Helix-turn-helix domain Pox_Ag35 PF03286.9 EPR77960.1 - 0.64 9.5 7.7 0.83 9.1 5.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec62 PF03839.11 EPR77960.1 - 0.71 9.2 4.3 0.82 9.0 3.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Ycf1 PF05758.7 EPR77960.1 - 1.4 6.5 12.2 1.6 6.3 8.5 1.0 1 0 0 1 1 1 0 Ycf1 Mpp10 PF04006.7 EPR77960.1 - 2.1 6.6 19.5 2.3 6.5 13.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF1510 PF07423.6 EPR77960.1 - 2.6 7.3 17.2 3 7.1 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Asp-B-Hydro_N PF05279.6 EPR77960.1 - 4.1 7.1 18.5 4.7 6.9 12.8 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Neur_chan_memb PF02932.11 EPR77960.1 - 4.2 7.1 6.8 4.6 7.0 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VID27 PF08553.5 EPR77960.1 - 6.5 4.8 17.6 7.6 4.6 12.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Spore_coat_CotO PF14153.1 EPR77960.1 - 7.8 5.8 17.2 9.9 5.5 11.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 EPR77960.1 - 7.9 4.3 18.2 9.3 4.1 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2956 PF11169.3 EPR77960.1 - 8.9 6.3 9.5 1.8 8.5 2.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) Aa_trans PF01490.13 EPR77961.1 - 1.5e-31 109.2 44.6 2.8e-31 108.4 30.9 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2754 PF10953.3 EPR77961.1 - 3.5 7.7 8.4 13 5.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) PIN_4 PF13638.1 EPR77962.1 - 6.5e-13 48.9 6.3 6.5e-13 48.9 4.4 2.8 2 1 0 2 2 2 1 PIN domain Barstar PF01337.13 EPR77964.1 - 0.16 11.8 1.2 0.49 10.2 0.1 2.2 1 1 1 2 2 2 0 Barstar (barnase inhibitor) Peptidase_S46 PF10459.4 EPR77964.1 - 1.7 6.9 13.3 2.1 6.6 9.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.10 EPR77964.1 - 3.4 6.7 20.0 3.9 6.5 13.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3461 PF11944.3 EPR77965.1 - 0.015 15.1 0.6 0.015 15.1 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3461) AAA_32 PF13654.1 EPR77965.1 - 0.025 13.2 4.8 0.0099 14.5 1.6 1.5 2 0 0 2 2 2 0 AAA domain POTRA_1 PF08478.5 EPR77965.1 - 0.079 13.0 0.0 2.8 8.0 0.0 2.8 2 1 1 3 3 3 0 POTRA domain, FtsQ-type LRR_4 PF12799.2 EPR77966.1 - 7e-23 79.7 46.2 2.9e-08 33.1 0.1 7.2 2 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77966.1 - 8e-21 73.5 38.8 3.2e-08 33.2 0.6 5.0 3 1 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EPR77966.1 - 4.8e-13 47.1 38.2 0.19 11.9 0.0 10.2 8 1 2 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR77966.1 - 1.3e-10 39.6 26.2 3.5 8.2 0.1 10.7 9 2 2 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 EPR77966.1 - 8.3e-06 25.3 30.2 3.8 7.8 0.4 8.9 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 EPR77968.1 - 4.1e-14 51.7 16.4 1e-07 31.3 0.2 3.2 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77968.1 - 6e-13 48.3 19.3 1.5e-07 31.0 0.5 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EPR77968.1 - 1.1e-07 30.9 1.0 1.1 9.7 0.0 5.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EPR77968.1 - 2.5e-06 26.7 17.4 0.16 12.0 0.1 5.6 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 EPR77968.1 - 0.00015 21.4 3.1 0.58 10.3 0.1 4.2 3 1 1 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 EPR77969.1 - 3.4e-12 45.9 32.2 2.8e-05 23.7 2.7 5.2 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EPR77969.1 - 4.9e-11 42.0 41.7 0.00011 21.6 3.0 6.5 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR77969.1 - 1.6e-05 24.2 37.8 0.24 11.5 0.2 8.4 7 1 2 9 9 9 6 Leucine Rich Repeat LRR_7 PF13504.1 EPR77969.1 - 0.00031 20.4 12.0 55 4.6 0.1 7.5 5 1 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EPR77969.1 - 0.015 15.2 28.1 2.9 8.2 0.2 7.9 6 1 1 7 7 7 0 Leucine Rich repeat G6PD_C PF02781.11 EPR77970.1 - 4.2e-22 78.3 4.3 9.5e-22 77.1 3.0 1.6 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPR77970.1 - 2.4e-13 50.7 1.6 1.1e-12 48.6 1.1 2.0 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EPR77970.1 - 0.042 14.3 0.0 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Lactamase_B PF00753.22 EPR77971.1 - 1.7e-05 24.5 1.7 0.00038 20.1 1.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily LRR_4 PF12799.2 EPR77972.1 - 5.7e-28 96.0 71.4 2.8e-05 23.6 0.8 9.3 6 2 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77972.1 - 3.4e-23 81.1 66.3 1.5e-05 24.6 2.5 7.8 3 3 5 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EPR77972.1 - 7.3e-11 40.5 75.0 0.022 14.7 0.0 15.6 15 1 1 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR77972.1 - 0.00022 20.8 47.0 3.6 8.1 0.0 13.5 14 0 0 14 14 14 4 Leucine rich repeat KH_5 PF13184.1 EPR77973.1 - 0.0084 15.8 6.5 0.099 12.4 2.8 2.1 2 0 0 2 2 2 2 NusA-like KH domain tRNA_int_endo PF01974.12 EPR77975.1 - 3.1e-15 55.7 0.8 3.6e-15 55.5 0.6 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain UTP15_C PF09384.5 EPR77976.1 - 0.023 14.3 3.5 0.93 9.1 0.1 2.7 2 1 1 3 3 3 0 UTP15 C terminal NOA36 PF06524.7 EPR77976.1 - 0.37 9.9 5.3 0.57 9.3 3.7 1.3 1 0 0 1 1 1 0 NOA36 protein EpsG PF14897.1 EPR77976.1 - 1.8 7.4 11.0 7.4 5.3 0.1 2.2 2 0 0 2 2 2 0 EpsG family PEPcase PF00311.12 EPR77977.1 - 0.052 11.4 1.5 0.059 11.2 1.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Sm_multidrug_ex PF06695.6 EPR77977.1 - 0.18 11.9 0.7 0.56 10.3 0.1 1.9 2 0 0 2 2 2 0 Putative small multi-drug export protein AAA_18 PF13238.1 EPR77977.1 - 1.5 9.1 8.7 2.1 8.6 6.0 1.3 1 0 0 1 1 1 0 AAA domain Tubulin PF00091.20 EPR77979.1 - 3.3e-66 223.1 0.0 4.6e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPR77979.1 - 1.2e-50 170.7 0.0 2e-50 170.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPR77979.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EPR77979.1 - 0.034 13.7 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Actin PF00022.14 EPR77980.1 - 1.6e-41 142.0 1.3 7.7e-20 70.6 0.4 3.1 1 1 1 2 2 2 2 Actin Ppx-GppA PF02541.11 EPR77980.1 - 0.035 13.2 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family 3HCDH_N PF02737.13 EPR77980.1 - 0.087 12.4 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MreB_Mbl PF06723.8 EPR77980.1 - 0.16 10.5 3.5 0.088 11.3 0.4 2.0 2 1 0 2 2 2 0 MreB/Mbl protein LRR_4 PF12799.2 EPR77981.1 - 1.8e-17 62.5 22.7 1.3e-07 31.0 0.0 4.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR77981.1 - 2.2e-14 52.9 16.3 3.1e-09 36.4 4.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPR77981.1 - 3.2e-07 29.4 13.1 0.96 9.7 0.2 5.8 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR77981.1 - 8.5e-06 25.1 5.8 2.4 8.7 0.2 5.8 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EPR77981.1 - 0.00022 20.9 12.4 0.14 12.3 0.4 5.5 5 0 0 5 5 5 2 Leucine Rich repeat ATP-synt_C PF00137.16 EPR77982.1 - 4.8e-07 29.5 21.1 1e-06 28.5 6.0 2.3 2 0 0 2 2 2 2 ATP synthase subunit C DUF4389 PF14333.1 EPR77982.1 - 1.4 8.6 4.3 25 4.6 0.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4389) DUF3814 PF12769.2 EPR77982.1 - 2.9 8.1 8.5 0.5 10.5 2.0 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF3814) DUF1836 PF08876.6 EPR77983.1 - 0.061 13.0 7.7 0.06 13.1 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1836) MGS PF02142.17 EPR77983.1 - 0.1 12.5 0.3 0.18 11.7 0.2 1.6 1 1 0 1 1 1 0 MGS-like domain DUF3410 PF11890.3 EPR77983.1 - 0.19 11.4 0.8 0.37 10.4 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3410) MSG PF02349.10 EPR77983.1 - 4.6 7.2 11.4 33 4.5 7.9 2.2 1 1 0 1 1 1 0 Major surface glycoprotein DUF2577 PF10844.3 EPR77984.1 - 1.8 8.6 9.6 2.5 8.1 2.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2577) Ribonuc_L-PSP PF01042.16 EPR77985.1 - 0.00071 19.3 0.4 0.46 10.2 0.0 2.2 2 0 0 2 2 2 2 Endoribonuclease L-PSP ISAV_HA PF06215.6 EPR77985.1 - 0.0013 17.0 0.2 0.8 7.9 0.0 2.1 2 0 0 2 2 2 2 Infectious salmon anaemia virus haemagglutinin Flavokinase PF01687.12 EPR77985.1 - 0.89 9.4 4.0 15 5.4 0.1 2.5 2 1 0 2 2 2 0 Riboflavin kinase DUF2762 PF10960.3 EPR77986.1 - 0.066 12.9 2.3 0.14 11.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) EOS1 PF12326.3 EPR77986.1 - 0.12 12.0 0.4 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 N-glycosylation protein DUF443 PF04276.7 EPR77986.1 - 0.15 11.4 1.9 0.44 9.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF443) EphA2_TM PF14575.1 EPR77986.1 - 0.57 10.6 0.0 0.57 10.6 0.0 3.0 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Cytomega_UL20A PF05984.7 EPR77987.1 - 0.18 12.0 1.9 0.37 11.0 1.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein DUF3139 PF11337.3 EPR77987.1 - 3.2 8.0 11.6 0.14 12.4 2.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) Peptidase_M17 PF00883.16 EPR77988.1 - 9.8e-105 349.8 0.0 1.2e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EPR77988.1 - 2.4e-05 24.1 0.0 4.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain MFS_1 PF07690.11 EPR77989.1 - 1.1e-11 44.1 28.9 1.2e-05 24.2 9.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-Fe_Oxy_2 PF10014.4 EPR77990.1 - 0.00068 19.0 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase RhoGAP PF00620.22 EPR77990.1 - 0.0016 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RepB-RCR_reg PF10723.4 EPR77990.1 - 0.1 12.3 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Replication regulatory protein RepB zf-B_box PF00643.19 EPR77991.1 - 2.4e-11 43.3 15.9 1.1e-08 34.7 2.6 2.6 2 0 0 2 2 2 2 B-box zinc finger IncA PF04156.9 EPR77991.1 - 0.5 9.9 5.9 0.95 9.0 4.0 1.6 1 1 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EPR77991.1 - 0.78 8.6 3.1 1.3 7.9 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.1 EPR77991.1 - 0.84 9.9 9.9 0.37 11.1 4.4 2.2 2 0 0 2 2 2 0 Snapin/Pallidin TAFII28 PF04719.9 EPR77992.1 - 4.3e-25 87.3 0.0 6.4e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DNA_ligase_A_N PF04675.9 EPR77992.1 - 0.065 13.0 0.6 0.45 10.3 0.4 2.0 1 1 1 2 2 2 0 DNA ligase N terminus Tyrosinase PF00264.15 EPR77993.1 - 1.2e-12 48.4 0.9 1.5e-12 48.2 0.2 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase EXS PF03124.9 EPR77994.1 - 5.5e-32 111.1 41.3 1.2e-31 110.0 28.6 1.6 1 0 0 1 1 1 1 EXS family UPF0257 PF06788.8 EPR77995.1 - 0.041 13.1 0.2 0.11 11.6 0.0 1.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0257) DDE_Tnp_IS1595 PF12762.2 EPR77997.1 - 8.1e-21 74.4 0.5 9.7e-21 74.1 0.4 1.1 1 0 0 1 1 1 1 ISXO2-like transposase domain ABC2_membrane_3 PF12698.2 EPR77998.1 - 0.42 9.6 3.7 0.47 9.4 2.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1533 PF07550.6 EPR78001.1 - 0.073 13.0 7.6 0.14 12.1 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) Oxidored_q3 PF00499.15 EPR78001.1 - 0.13 12.0 1.8 0.16 11.7 1.3 1.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MIP-T3 PF10243.4 EPR78003.1 - 1.1e-07 30.7 80.4 1.1e-07 30.7 55.8 2.6 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 LRR_4 PF12799.2 EPR78005.1 - 8.6e-06 25.2 4.1 8.6e-06 25.2 2.8 2.3 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78005.1 - 2.6e-05 23.8 2.8 2.6e-05 23.8 1.9 2.0 2 1 1 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EPR78005.1 - 0.00043 19.9 12.4 0.025 14.5 0.3 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EPR78005.1 - 0.0054 16.7 4.9 0.67 10.4 0.2 3.5 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EPR78005.1 - 0.084 12.9 5.3 0.28 11.3 0.1 3.5 3 1 0 3 3 3 0 Leucine Rich repeat Chordopox_E11 PF06138.7 EPR78006.1 - 0.02 15.0 1.5 0.022 14.8 1.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Glyco_hydro_17 PF00332.13 EPR78006.1 - 0.068 12.1 0.1 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 PBP_sp32 PF07222.7 EPR78007.1 - 2.1 7.4 11.9 1.4 8.0 0.1 2.2 1 1 1 2 2 2 0 Proacrosin binding protein sp32 Dynein_light PF01221.13 EPR78008.1 - 9.7e-12 44.7 0.6 1.2e-11 44.3 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF2891 PF11199.3 EPR78008.1 - 0.027 13.0 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Ground-like PF04155.13 EPR78008.1 - 0.032 14.5 0.6 0.047 13.9 0.4 1.5 1 1 0 1 1 1 0 Ground-like domain DUF3819 PF12842.2 EPR78008.1 - 0.068 12.8 0.4 0.086 12.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Pollen_allerg_1 PF01357.16 EPR78008.1 - 0.073 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Pollen allergen DUF4319 PF14203.1 EPR78008.1 - 1.8 8.1 6.4 3.8 7.1 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4319) Symplekin_C PF12295.3 EPR78009.1 - 4.5e-16 59.2 6.3 1.2e-15 57.9 4.4 1.7 1 1 0 1 1 1 1 Symplekin tight junction protein C terminal S-AdoMet_synt_M PF02772.11 EPR78009.1 - 0.03 14.2 1.0 0.045 13.6 0.4 1.6 1 1 0 1 1 1 0 S-adenosylmethionine synthetase, central domain Proteasome PF00227.21 EPR78010.1 - 6.7e-39 133.1 0.1 8.1e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPR78010.1 - 1.4e-09 37.1 0.2 4.2e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SpoVIF PF14069.1 EPR78010.1 - 0.028 14.1 1.7 0.028 14.1 1.2 2.0 2 0 0 2 2 2 0 Stage VI sporulation protein F DUF2746 PF10874.3 EPR78010.1 - 0.32 11.2 5.0 0.49 10.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Peptidase_M48 PF01435.13 EPR78011.1 - 2e-08 34.0 0.8 2e-08 34.0 0.6 2.2 2 2 0 2 2 2 1 Peptidase family M48 Ycf66_N PF07444.6 EPR78011.1 - 0.019 14.6 0.2 0.019 14.6 0.2 2.7 2 0 0 2 2 2 0 Ycf66 protein N-terminus Gemini_mov PF01708.11 EPR78011.1 - 8.4 6.0 7.0 5.3 6.6 0.1 2.8 2 0 0 2 2 2 0 Geminivirus putative movement protein Aa_trans PF01490.13 EPR78012.1 - 7.8e-36 123.4 45.8 1e-35 123.0 31.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Hexapep PF00132.19 EPR78013.1 - 6e-06 25.5 12.5 0.0012 18.2 4.0 3.1 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) CfAFP PF05264.6 EPR78013.1 - 0.007 16.1 1.7 0.015 15.1 1.1 1.5 1 0 0 1 1 1 1 Choristoneura fumiferana antifreeze protein (CfAFP) PfkB PF00294.19 EPR78014.1 - 6.8e-19 68.1 0.0 9.1e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Metallophos PF00149.23 EPR78015.1 - 1.9e-37 128.6 0.5 2.5e-37 128.2 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glutaredoxin PF00462.19 EPR78016.1 - 1.3e-12 47.5 0.1 1.5e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin YodA PF09223.6 EPR78016.1 - 0.022 14.4 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 YodA lipocalin-like domain ACPS PF01648.15 EPR78016.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Aa_trans PF01490.13 EPR78017.1 - 1.3e-31 109.5 48.7 1.7e-31 109.1 33.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EPR78017.1 - 0.72 8.3 52.8 0.22 10.0 15.6 2.2 1 1 1 2 2 2 0 Amino acid permease LRR_8 PF13855.1 EPR78018.1 - 7e-25 86.5 56.3 1e-08 34.7 5.1 8.5 5 3 4 9 9 9 6 Leucine rich repeat LRR_4 PF12799.2 EPR78018.1 - 2.6e-24 84.3 66.6 1.3e-06 27.8 1.9 10.5 10 2 2 12 12 12 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78018.1 - 2.2e-15 54.3 47.3 0.013 15.3 0.2 14.9 15 0 0 15 15 15 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR78018.1 - 0.066 13.4 44.9 0.82 10.1 0.2 12.8 14 0 0 14 14 14 0 Leucine rich repeat PI31_Prot_C PF08577.6 EPR78019.1 - 0.11 13.2 6.4 0.41 11.3 4.4 2.1 1 1 0 1 1 1 0 PI31 proteasome regulator IF4E PF01652.13 EPR78020.1 - 4.1e-39 133.7 6.8 4.7e-39 133.5 4.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Gar1 PF04410.9 EPR78021.1 - 5.9e-20 71.2 4.4 5.9e-20 71.2 3.0 1.2 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region CDC45 PF02724.9 EPR78021.1 - 0.13 10.2 5.6 0.16 9.9 3.9 1.0 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.21 EPR78022.1 - 1e-39 135.1 0.0 1.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPR78022.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain RED_C PF07807.6 EPR78023.1 - 0.072 13.2 1.9 0.1 12.7 1.3 1.2 1 0 0 1 1 1 0 RED-like protein C-terminal region HMA PF00403.21 EPR78023.1 - 0.2 11.8 2.2 0.45 10.6 1.5 1.7 1 1 0 1 1 1 0 Heavy-metal-associated domain Cytadhesin_P30 PF07271.6 EPR78023.1 - 0.31 10.2 1.8 0.35 10.0 1.3 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Arc_PepC_II PF06847.6 EPR78023.1 - 0.9 10.0 3.2 0.57 10.6 0.7 1.7 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Ribosomal_S4e PF00900.15 EPR78024.1 - 6e-24 83.5 1.0 1.1e-23 82.6 0.7 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPR78024.1 - 1.5e-19 69.5 0.9 2.6e-19 68.7 0.6 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPR78024.1 - 6.2e-05 22.3 0.1 0.00014 21.2 0.1 1.6 1 0 0 1 1 1 1 S4 domain HAS-barrel PF09378.5 EPR78024.1 - 0.62 10.0 5.1 5 7.0 3.5 2.5 1 1 0 1 1 1 0 HAS barrel domain LCAT PF02450.10 EPR78025.1 - 3e-57 194.3 1.8 1.2e-56 192.4 1.3 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EPR78025.1 - 0.0037 16.8 0.0 0.0071 15.9 0.0 1.4 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 EPR78025.1 - 0.015 14.5 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ABC_tran PF00005.22 EPR78026.1 - 7.7e-26 91.0 0.0 1.3e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPR78026.1 - 1e-07 32.2 2.1 1.2e-05 25.4 0.2 4.0 2 2 2 4 4 4 2 AAA domain AAA_15 PF13175.1 EPR78026.1 - 1e-06 28.0 0.2 0.0063 15.6 0.9 2.4 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EPR78026.1 - 4.5e-06 26.0 2.8 2e-05 23.9 0.8 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane PF01061.19 EPR78026.1 - 6.2e-05 22.2 37.9 0.00042 19.5 18.1 2.2 1 1 1 2 2 2 1 ABC-2 type transporter AAA_17 PF13207.1 EPR78026.1 - 9.8e-05 23.1 0.0 0.00024 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR78026.1 - 0.00053 20.2 0.2 0.003 17.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPR78026.1 - 0.00065 19.1 0.3 0.0013 18.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EPR78026.1 - 0.0023 17.3 0.0 0.0052 16.2 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPR78026.1 - 0.0028 17.6 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPR78026.1 - 0.0048 17.0 0.2 0.01 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EPR78026.1 - 0.0094 16.3 0.9 0.031 14.6 0.6 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPR78026.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EPR78026.1 - 0.014 14.3 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EPR78026.1 - 0.024 14.5 1.0 0.42 10.5 0.0 2.6 1 1 2 3 3 3 0 AAA domain AAA_19 PF13245.1 EPR78026.1 - 0.027 14.1 0.4 0.055 13.2 0.3 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EPR78026.1 - 0.04 13.8 0.2 0.096 12.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EPR78026.1 - 0.042 13.2 0.0 0.099 12.0 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EPR78026.1 - 0.043 13.3 0.6 0.075 12.6 0.4 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPR78026.1 - 0.046 13.3 0.3 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EPR78026.1 - 0.049 13.2 0.4 0.11 12.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EPR78026.1 - 0.055 13.6 0.9 0.2 11.8 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPR78026.1 - 0.097 12.5 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPR78026.1 - 0.11 12.2 0.1 2 8.0 0.1 2.3 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 EPR78026.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EPR78026.1 - 0.12 11.8 0.4 0.18 11.1 0.3 1.2 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EPR78026.1 - 0.17 11.3 0.1 0.32 10.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EPR78026.1 - 0.2 10.7 1.5 1.1 8.3 0.6 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Tetraspannin PF00335.15 EPR78027.1 - 5.8e-08 32.2 22.4 1.4e-07 31.0 15.5 1.7 1 1 0 1 1 1 1 Tetraspanin family RabGAP-TBC PF00566.13 EPR78028.1 - 8.8e-44 149.5 7.4 8.8e-44 149.5 5.2 2.9 2 1 0 3 3 3 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EPR78029.1 - 5.8e-68 228.8 0.4 6.7e-68 228.6 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78029.1 - 4.3e-36 124.3 0.1 1.3e-35 122.7 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78029.1 - 3.1e-05 23.0 0.0 5.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPR78029.1 - 0.032 13.9 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EPR78029.1 - 0.035 13.1 0.1 0.069 12.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPR78029.1 - 0.048 12.9 4.6 0.026 13.8 1.4 2.0 2 1 0 2 2 2 0 RIO1 family Ribul_P_3_epim PF00834.14 EPR78030.1 - 9.8e-29 99.8 0.2 1.4e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family RTC PF01137.16 EPR78031.1 - 6.5e-27 93.7 0.0 8.8e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EPR78031.1 - 3.8e-10 39.7 0.0 6.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Gemini_AL3 PF01407.12 EPR78031.1 - 0.092 12.2 0.8 0.21 11.0 0.1 2.0 2 0 0 2 2 2 0 Geminivirus AL3 protein U3_assoc_6 PF08640.6 EPR78034.1 - 3.8e-18 65.0 7.0 3.8e-18 65.0 4.8 2.6 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 Chlam_vir PF05475.6 EPR78034.1 - 0.03 13.4 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D HCNGP PF07818.8 EPR78036.1 - 5.4 7.1 14.3 2.6 8.1 4.5 2.5 1 1 2 3 3 3 0 HCNGP-like protein DUF506 PF04720.7 EPR78037.1 - 0.04 13.5 9.3 0.22 11.1 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF506) DUF1736 PF08409.6 EPR78037.1 - 1.6 8.3 6.1 0.8 9.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1736) MutL_C PF08676.6 EPR78039.1 - 7.7e-08 32.0 0.3 4e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 MutL C terminal dimerisation domain dsDNA_bind PF01984.15 EPR78041.1 - 0.0011 18.8 0.1 0.0018 18.2 0.1 1.3 1 1 0 1 1 1 1 Double-stranded DNA-binding domain TPPII_N PF12583.3 EPR78041.1 - 0.011 15.8 0.3 0.012 15.7 0.2 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal GGDN PF05165.7 EPR78041.1 - 0.051 12.6 0.0 0.056 12.4 0.0 1.0 1 0 0 1 1 1 0 GGDN family vATP-synt_E PF01991.13 EPR78041.1 - 0.064 12.5 1.7 0.076 12.2 1.2 1.0 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Pox_A28 PF04584.9 EPR78041.1 - 0.073 12.9 0.6 0.078 12.8 0.4 1.2 1 0 0 1 1 1 0 Poxvirus A28 family Rpr2 PF04032.11 EPR78043.1 - 7.9e-09 35.2 4.6 1.4e-08 34.4 3.2 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain IFRD PF05004.8 EPR78043.1 - 0.021 13.9 0.4 0.023 13.8 0.3 1.0 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) PRESAN PF09687.5 EPR78043.1 - 0.023 14.7 11.0 0.037 14.0 7.6 1.4 1 1 0 1 1 1 0 Plasmodium RESA N-terminal zf-UBR PF02207.15 EPR78043.1 - 0.028 14.1 0.6 0.04 13.6 0.4 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-BED PF02892.10 EPR78043.1 - 1.6 8.5 4.6 4.2 7.1 3.2 1.8 1 1 0 1 1 1 0 BED zinc finger CTP_transf_1 PF01148.15 EPR78044.1 - 1.5e-55 188.6 28.7 1.9e-55 188.3 19.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family ETRAMP PF09716.5 EPR78045.1 - 2.7 8.0 11.2 0.76 9.7 4.7 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.20 EPR78046.1 - 1.7e-32 112.6 17.6 1.4e-29 103.0 12.2 3.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78046.1 - 3.6e-13 49.1 1.4 6.3e-12 45.1 0.4 2.8 3 0 0 3 3 3 1 Protein tyrosine kinase DUF565 PF04483.7 EPR78047.1 - 0.093 12.8 0.2 0.27 11.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF565) DNA_pol_B_exo1 PF03104.14 EPR78048.1 - 1e-44 152.7 11.8 1e-44 152.7 8.2 4.3 3 2 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EPR78048.1 - 7.8e-21 74.3 12.6 7.8e-21 74.3 8.7 3.2 1 1 0 2 2 2 1 DNA polymerase family B Ivy PF08816.6 EPR78049.1 - 0.0064 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of vertebrate lysozyme (Ivy) Myb_DNA-binding PF00249.26 EPR78050.1 - 3.7e-08 33.2 0.2 9.7e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPR78050.1 - 3.6e-07 30.1 1.9 6.8e-07 29.3 0.1 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain HTH_38 PF13936.1 EPR78050.1 - 0.0047 16.4 0.1 0.0092 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Choline_kin_N PF04428.9 EPR78051.1 - 0.1 12.0 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus Ras PF00071.17 EPR78052.1 - 1.1e-56 190.7 2.1 1.7e-56 190.0 1.4 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR78052.1 - 7.6e-18 65.1 0.7 1e-17 64.7 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPR78052.1 - 7.4e-17 61.1 2.2 7.8e-17 61.0 0.2 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPR78052.1 - 8.2e-09 34.9 0.2 1.1e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPR78052.1 - 1.7e-08 34.1 0.1 1.8e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPR78052.1 - 2.3e-06 26.9 0.1 4.8e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPR78052.1 - 3.3e-06 27.0 0.0 6.6e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EPR78052.1 - 0.0029 16.6 0.5 0.18 10.7 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_14 PF13173.1 EPR78052.1 - 0.0042 16.9 0.5 0.013 15.4 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPR78052.1 - 0.0066 15.5 6.5 0.015 14.4 4.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EPR78052.1 - 0.016 15.1 0.1 0.059 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EPR78052.1 - 0.016 14.4 0.2 0.036 13.3 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EPR78052.1 - 0.017 14.6 0.3 0.036 13.5 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation UQ_con PF00179.21 EPR78053.1 - 9.8e-28 96.3 0.1 1e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPR78053.1 - 0.054 13.3 0.1 0.074 12.9 0.1 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EPR78053.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Dus PF01207.12 EPR78054.1 - 5.5e-55 186.3 0.0 2e-53 181.2 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EPR78054.1 - 0.00063 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Oxidored_FMN PF00724.15 EPR78054.1 - 0.0055 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ThiG PF05690.9 EPR78054.1 - 0.034 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 EPR78054.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase LRR_4 PF12799.2 EPR78055.1 - 2.9e-34 116.1 67.9 1.6e-07 30.8 0.1 9.5 6 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78055.1 - 1.4e-31 108.0 61.2 1.3e-07 31.2 1.4 8.3 6 2 2 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EPR78055.1 - 2.3e-15 54.2 66.6 0.21 11.7 0.3 15.3 13 1 2 15 15 15 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR78055.1 - 1.9e-06 27.1 43.7 2 8.9 0.2 13.3 14 0 0 14 14 14 4 Leucine rich repeat LRR_9 PF14580.1 EPR78055.1 - 0.00064 19.3 16.5 0.013 15.1 0.9 3.7 3 0 0 3 3 3 3 Leucine-rich repeat DUF2397 PF09660.5 EPR78055.1 - 0.34 9.4 0.2 0.51 8.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) WD40 PF00400.27 EPR78056.1 - 1.2e-09 37.6 1.8 1.5e-08 34.1 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Acetyltransf_7 PF13508.1 EPR78057.1 - 1.4e-07 31.5 0.1 2.6e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPR78057.1 - 1.4e-05 25.0 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPR78057.1 - 0.00054 20.0 0.0 0.00068 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPR78057.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Med26 PF08711.6 EPR78057.1 - 0.083 12.4 0.2 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 TFIIS helical bundle-like domain PGI PF00342.14 EPR78058.1 - 2e-154 514.6 7.3 2.6e-154 514.2 5.1 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Methyltransf_8 PF05148.10 EPR78059.1 - 5.9e-41 140.4 2.5 8e-41 140.0 1.7 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_31 PF13847.1 EPR78059.1 - 2.3e-06 27.2 2.6 0.00043 19.8 0.3 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EPR78059.1 - 5.1e-05 23.0 0.0 7.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPR78059.1 - 0.00012 22.5 0.3 0.00052 20.4 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPR78059.1 - 0.0081 15.3 0.0 0.053 12.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EPR78059.1 - 0.0085 16.5 0.6 0.13 12.6 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPR78059.1 - 0.031 13.6 0.5 2.1 7.6 0.1 2.4 1 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EPR78059.1 - 0.048 14.2 0.8 3.5 8.2 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain N6_N4_Mtase PF01555.13 EPR78059.1 - 0.81 9.1 6.9 0.41 10.0 0.2 2.1 1 1 1 2 2 2 0 DNA methylase Pkinase PF00069.20 EPR78060.1 - 6.5e-41 140.1 2.3 6.5e-41 140.1 1.6 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78060.1 - 1.6e-22 79.8 0.1 2.9e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EPR78060.1 - 5.9e-07 29.0 0.1 1.2e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EPR78060.1 - 5.7e-06 25.4 0.0 9.1e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPR78060.1 - 0.00092 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR78060.1 - 0.0039 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SNARE PF05739.14 EPR78063.1 - 0.00038 20.0 1.6 0.00038 20.0 1.1 2.4 3 0 0 3 3 3 1 SNARE domain Nnf1 PF03980.9 EPR78063.1 - 0.0035 17.3 1.8 0.0035 17.3 1.2 2.5 2 1 0 2 2 2 1 Nnf1 TMF_DNA_bd PF12329.3 EPR78063.1 - 3.2 7.6 13.0 0.17 11.6 1.2 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4482 PF14818.1 EPR78063.1 - 8.4 7.0 9.3 16 6.1 1.2 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4482) LRR_4 PF12799.2 EPR78064.1 - 8.8e-10 37.9 14.3 2.5e-05 23.7 3.6 4.1 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78064.1 - 4.7e-08 32.6 7.3 1.2e-05 24.9 2.0 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR78064.1 - 1.7e-06 27.2 9.4 0.073 13.1 0.5 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EPR78064.1 - 0.0027 17.6 11.6 1.1 9.5 0.2 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 EPR78064.1 - 0.024 14.7 5.5 2.9 8.4 0.1 4.7 5 0 0 5 5 5 0 Leucine rich repeat UCH PF00443.24 EPR78064.1 - 0.13 11.3 3.3 2.4 7.1 2.3 2.2 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase LRR_5 PF13306.1 EPR78064.1 - 0.23 11.1 10.3 0.14 11.8 4.0 2.7 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) YrzO PF14142.1 EPR78065.1 - 0.038 13.6 0.1 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 YrzO-like protein RRM_1 PF00076.17 EPR78066.1 - 1.1e-07 31.3 0.0 2.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR78066.1 - 0.00043 20.1 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR78066.1 - 0.0012 18.6 0.4 0.0029 17.4 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 EPR78067.1 - 3.4e-18 65.6 0.0 4.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 EPR78067.1 - 0.034 13.4 0.0 0.086 12.1 0.0 1.7 1 0 0 1 1 1 0 EF hand SBDS PF01172.13 EPR78068.1 - 1.5e-12 47.1 10.7 2.4e-11 43.2 0.1 3.3 3 1 1 4 4 4 2 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EPR78068.1 - 0.018 14.7 6.3 0.046 13.4 4.4 1.8 1 1 0 1 1 1 0 SBDS protein C-terminal domain IF2_N PF04760.10 EPR78068.1 - 0.49 10.1 4.1 1.2 8.8 0.2 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region zf-RING_2 PF13639.1 EPR78069.1 - 6.1e-09 35.5 6.5 9.6e-09 34.9 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPR78069.1 - 1.3e-06 27.9 8.3 2.2e-06 27.2 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPR78069.1 - 7.7e-06 25.9 7.6 1.8e-05 24.7 5.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPR78069.1 - 1.5e-05 24.6 6.8 2.7e-05 23.8 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPR78069.1 - 0.0002 20.9 5.7 0.00038 20.0 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR78069.1 - 0.00021 21.2 8.9 0.00039 20.3 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EPR78069.1 - 0.0014 18.3 4.4 0.0027 17.4 3.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPR78069.1 - 0.0025 17.6 3.7 0.0066 16.2 2.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EPR78069.1 - 0.0034 16.8 4.6 0.0069 15.8 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EPR78069.1 - 0.076 12.8 6.2 0.15 11.9 4.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EPR78069.1 - 0.099 12.6 7.1 1.2 9.1 5.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Endonuclease_7 PF02945.10 EPR78069.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Recombination endonuclease VII RINGv PF12906.2 EPR78069.1 - 0.21 11.6 7.4 0.6 10.1 5.0 1.8 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.6 EPR78069.1 - 0.34 10.9 6.1 0.58 10.1 4.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-Di19 PF05605.7 EPR78069.1 - 0.69 10.0 3.2 2.3 8.4 0.2 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.1 EPR78069.1 - 2.5 7.8 8.8 0.47 10.2 2.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Rpr2 PF04032.11 EPR78069.1 - 9.3 6.2 7.7 4.9 7.0 1.3 2.6 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HEAT PF02985.17 EPR78070.1 - 4.9e-05 23.0 0.1 4.4 7.6 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Biotin_lipoyl PF00364.17 EPR78071.1 - 7.7e-10 38.2 2.1 1.5e-09 37.3 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EPR78071.1 - 0.0053 16.4 0.1 0.085 12.5 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like DUF3952 PF13130.1 EPR78071.1 - 0.8 9.7 7.2 0.1 12.5 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) LRR_4 PF12799.2 EPR78072.1 - 1.2e-12 47.1 14.7 4.7e-06 26.0 0.1 4.2 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78072.1 - 1.8e-11 43.5 8.5 8.2e-07 28.6 1.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPR78072.1 - 3e-06 26.4 11.4 0.034 14.1 0.1 5.8 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EPR78072.1 - 4.1e-06 26.1 1.7 0.95 9.9 0.0 5.2 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EPR78072.1 - 0.0093 15.9 7.5 3.9 7.8 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_5 PF13306.1 EPR78072.1 - 0.092 12.4 6.1 0.04 13.6 0.8 2.1 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) DUF866 PF05907.8 EPR78075.1 - 1.2e-10 41.1 3.5 1.3e-10 40.9 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-like PF04071.7 EPR78075.1 - 0.25 11.0 2.2 0.36 10.5 0.3 2.0 1 1 1 2 2 2 0 Cysteine-rich small domain E7 PF00527.13 EPR78075.1 - 0.53 10.4 2.9 10 6.3 0.2 2.3 1 1 1 2 2 2 0 E7 protein, Early protein Peptidase_C50 PF03568.12 EPR78076.1 - 2.9e-08 32.7 12.1 4e-07 29.0 8.3 2.6 1 1 0 1 1 1 1 Peptidase family C50 DUF1758 PF05585.7 EPR78077.1 - 0.0032 17.0 0.4 0.0069 15.9 0.3 1.5 1 0 0 1 1 1 1 Putative peptidase (DUF1758) UPF0114 PF03350.11 EPR78077.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 zf-HC5HC2H_2 PF13832.1 EPR78078.1 - 9.8e-23 80.2 5.7 9.8e-23 80.2 4.0 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain Bromodomain PF00439.20 EPR78078.1 - 3.7e-15 55.6 7.1 3.7e-15 55.6 4.9 3.5 1 1 2 3 3 3 1 Bromodomain zf-HC5HC2H PF13771.1 EPR78078.1 - 4.9e-14 52.2 4.1 4.9e-14 52.2 2.8 2.9 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EPR78078.1 - 3.5e-11 42.2 4.9 3.5e-11 42.2 3.4 3.0 4 0 0 4 4 4 1 PHD-finger PHD PF00628.24 EPR78078.1 - 5.9e-08 32.2 8.3 5.9e-08 32.2 5.7 3.8 5 0 0 5 5 5 1 PHD-finger zf-PHD-like PF15446.1 EPR78078.1 - 0.0055 16.0 2.2 0.0055 16.0 1.5 2.1 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain CRPV_capsid PF08762.5 EPR78079.1 - 0.04 13.3 0.9 0.078 12.4 0.6 1.4 1 0 0 1 1 1 0 CRPV capsid protein like Enkurin PF13864.1 EPR78079.1 - 0.5 10.5 3.4 1.6 8.9 2.3 1.8 1 0 0 1 1 1 0 Calmodulin-binding Kinesin PF00225.18 EPR78080.1 - 1.1e-89 300.4 9.6 1.1e-89 300.4 6.6 1.8 2 1 0 2 2 2 1 Kinesin motor domain GDI PF00996.13 EPR78081.1 - 3.2e-84 282.7 6.1 6.3e-64 215.9 2.2 2.0 2 0 0 2 2 2 2 GDP dissociation inhibitor Ssl1 PF04056.9 EPR78082.1 - 1.1e-21 77.2 0.8 1.7e-21 76.7 0.6 1.2 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EPR78082.1 - 0.0022 18.1 0.0 0.014 15.4 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain CoA_binding_2 PF13380.1 EPR78082.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain DUF2256 PF10013.4 EPR78082.1 - 0.24 11.1 1.4 0.42 10.4 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) TMCO5 PF14992.1 EPR78082.1 - 8.4 5.4 9.5 0.39 9.7 2.3 1.8 2 1 0 2 2 2 0 TMCO5 family PRK PF00485.13 EPR78083.1 - 1.8e-15 57.0 0.6 2.6e-14 53.2 0.4 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EPR78083.1 - 4.5e-10 40.3 0.0 1.5e-09 38.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR78083.1 - 1.3e-07 31.9 2.4 1.6e-07 31.6 0.6 2.0 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EPR78083.1 - 4.5e-06 26.5 0.0 3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EPR78083.1 - 1e-05 24.9 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF258 PF03193.11 EPR78083.1 - 5.5e-05 22.4 0.0 8.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EPR78083.1 - 7.4e-05 22.3 0.0 0.0059 16.1 0.0 2.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPR78083.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain PPV_E1_C PF00519.12 EPR78083.1 - 0.00045 18.9 0.0 0.00076 18.2 0.0 1.3 1 0 0 1 1 1 1 Papillomavirus helicase AAA_14 PF13173.1 EPR78083.1 - 0.00061 19.6 1.9 0.002 18.0 1.3 2.2 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPR78083.1 - 0.00075 18.4 0.1 0.0017 17.2 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_PrkA PF08298.6 EPR78083.1 - 0.00092 17.9 0.4 0.002 16.9 0.0 1.7 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 EPR78083.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EPR78083.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SE PF00437.15 EPR78083.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein APS_kinase PF01583.15 EPR78083.1 - 0.0018 17.9 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EPR78083.1 - 0.002 17.2 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EPR78083.1 - 0.0021 18.2 0.1 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EPR78083.1 - 0.0055 16.9 0.7 0.017 15.4 0.5 2.0 1 1 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.9 EPR78083.1 - 0.0069 15.4 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain MutS_V PF00488.16 EPR78083.1 - 0.0097 15.3 0.1 0.021 14.2 0.0 1.5 2 0 0 2 2 1 1 MutS domain V Arch_ATPase PF01637.13 EPR78083.1 - 0.01 15.5 7.0 0.066 12.9 4.9 2.1 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EPR78083.1 - 0.017 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EPR78083.1 - 0.018 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 EPR78083.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNA12 PF10443.4 EPR78083.1 - 0.025 13.0 0.1 0.037 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_29 PF13555.1 EPR78083.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EPR78083.1 - 0.046 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EPR78083.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_31 PF13614.1 EPR78083.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPR78083.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.17 EPR78083.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EPR78083.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CobU PF02283.11 EPR78083.1 - 0.15 11.4 0.1 0.44 9.9 0.0 1.8 2 0 0 2 2 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_23 PF13476.1 EPR78083.1 - 0.93 9.7 14.4 1.5 9.0 9.8 1.5 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.2 EPR78084.1 - 3.6e-28 96.6 90.8 6.4e-06 25.6 0.1 10.8 5 3 7 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78084.1 - 1.4e-27 95.1 77.9 1.1e-07 31.5 4.0 9.4 6 2 3 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EPR78084.1 - 2.3e-14 51.1 73.4 0.07 13.1 0.2 16.1 15 1 1 16 16 16 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR78084.1 - 3.2e-08 32.4 51.9 1.7 9.1 0.4 14.3 15 0 0 15 15 15 5 Leucine rich repeat LRR_6 PF13516.1 EPR78084.1 - 0.62 10.2 0.0 0.26 11.4 0.5 13.9 15 1 0 15 15 15 0 Leucine Rich repeat Sigma54_DBD PF04552.8 EPR78085.1 - 0.043 13.3 0.1 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Thioredoxin_2 PF13098.1 EPR78085.1 - 0.069 13.3 2.0 0.33 11.1 0.2 2.3 1 1 1 2 2 2 0 Thioredoxin-like domain IF4E PF01652.13 EPR78086.1 - 7.2e-24 84.1 0.0 8.5e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Propep_M14 PF02244.11 EPR78086.1 - 0.022 14.4 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Carboxypeptidase activation peptide RabGAP-TBC PF00566.13 EPR78087.1 - 4.4e-30 104.7 11.3 6.5e-26 91.1 3.1 2.3 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DRIM PF07539.7 EPR78087.1 - 0.095 12.1 0.1 0.095 12.1 0.1 2.5 3 0 0 3 3 3 0 Down-regulated in metastasis Metallophos PF00149.23 EPR78088.1 - 2e-21 76.3 2.2 3.6e-21 75.4 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mre11_DNA_bind PF04152.9 EPR78088.1 - 3.3e-15 56.3 13.7 4.6e-14 52.6 2.6 3.8 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos_2 PF12850.2 EPR78088.1 - 7.1e-12 45.4 0.1 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_assoc_C PF09821.4 EPR78088.1 - 0.53 10.5 4.1 1.2 9.3 0.6 2.4 1 1 1 2 2 2 0 C-terminal AAA-associated domain RINGv PF12906.2 EPR78089.1 - 1.9e-09 37.4 7.4 2.8e-09 36.8 5.1 1.3 1 0 0 1 1 1 1 RING-variant domain PMP22_Claudin PF00822.15 EPR78089.1 - 0.0036 16.9 0.4 0.0066 16.1 0.3 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family zf-RING_2 PF13639.1 EPR78089.1 - 0.06 13.1 6.2 0.097 12.5 4.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EPR78089.1 - 0.23 11.1 5.3 0.42 10.3 3.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec6 PF06046.8 EPR78090.1 - 3.9e-69 233.2 34.2 3.1e-47 160.9 3.0 2.8 2 1 1 3 3 3 2 Exocyst complex component Sec6 EF1G PF00647.14 EPR78090.1 - 0.15 11.7 7.7 2.7 7.7 0.1 3.6 2 1 0 3 3 3 0 Elongation factor 1 gamma, conserved domain Synaptobrevin PF00957.16 EPR78091.1 - 3.9e-07 29.5 0.2 3.9e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EPR78091.1 - 0.0046 16.4 0.1 0.26 10.8 0.0 2.4 2 0 0 2 2 2 1 Regulated-SNARE-like domain Peptidase_C39 PF03412.10 EPR78091.1 - 0.038 13.8 0.3 1.1 9.1 0.2 2.3 1 1 0 1 1 1 0 Peptidase C39 family RRF_GI PF12614.3 EPR78091.1 - 0.045 13.5 0.3 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Ribosome recycling factor DUF4239 PF14023.1 EPR78091.1 - 0.067 12.5 0.8 0.14 11.5 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) APP_E2 PF12925.2 EPR78091.1 - 0.13 11.7 1.3 0.27 10.8 0.0 2.0 2 1 0 2 2 2 0 E2 domain of amyloid precursor protein Laminin_II PF06009.7 EPR78091.1 - 0.38 10.4 3.1 0.29 10.9 0.7 1.8 2 0 0 2 2 2 0 Laminin Domain II KGK PF08872.5 EPR78091.1 - 0.51 10.5 5.5 6.6 6.9 0.4 2.5 1 1 1 2 2 2 0 KGK domain ORMDL PF04061.9 EPR78093.1 - 2.7e-33 114.4 8.3 4e-33 113.8 5.8 1.3 1 0 0 1 1 1 1 ORMDL family DUF258 PF03193.11 EPR78094.1 - 0.00012 21.3 0.5 0.00021 20.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Med10 PF09748.4 EPR78094.1 - 0.049 13.4 4.9 0.094 12.5 3.4 1.5 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex NB PF04159.8 EPR78094.1 - 2.8 7.7 9.3 0.43 10.3 2.3 2.2 1 1 1 2 2 2 0 NB glycoprotein DSHCT PF08148.7 EPR78095.1 - 5.2e-49 165.9 0.3 1.3e-48 164.6 0.0 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EPR78095.1 - 3.3e-21 75.5 0.0 8e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR78095.1 - 2.4e-06 27.2 0.0 6.1e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EPR78095.1 - 0.024 13.5 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF162 PF02589.10 EPR78096.1 - 0.2 11.1 1.4 5.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 PRCC PF10253.4 EPR78096.1 - 0.28 11.8 7.0 0.53 10.9 4.9 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting AAA PF00004.24 EPR78098.1 - 2.4e-42 144.2 0.0 4.2e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPR78098.1 - 3.6e-07 30.3 0.0 0.00036 20.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 EPR78098.1 - 1.6e-06 28.1 0.0 5.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPR78098.1 - 2.9e-06 27.0 0.1 1.6e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPR78098.1 - 1.6e-05 25.0 0.0 3.7e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPR78098.1 - 0.00012 22.9 0.1 0.0003 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPR78098.1 - 0.00018 20.6 0.0 0.00037 19.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EPR78098.1 - 0.00022 20.2 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EPR78098.1 - 0.00069 19.3 0.2 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EPR78098.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPR78098.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EPR78098.1 - 0.002 18.2 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 EPR78098.1 - 0.002 17.8 0.1 0.021 14.5 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 EPR78098.1 - 0.0021 17.9 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPR78098.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EPR78098.1 - 0.0028 17.5 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR78098.1 - 0.0029 17.8 0.0 0.0064 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EPR78098.1 - 0.0043 16.7 0.9 0.011 15.4 0.0 2.2 3 1 0 3 3 2 1 NTPase AAA_3 PF07726.6 EPR78098.1 - 0.0043 16.6 0.0 0.018 14.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EPR78098.1 - 0.0064 15.2 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EPR78098.1 - 0.0065 15.6 0.1 0.018 14.2 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EPR78098.1 - 0.0085 15.7 0.0 0.48 10.0 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_25 PF13481.1 EPR78098.1 - 0.012 15.0 0.4 0.13 11.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EPR78098.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPR78098.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EPR78098.1 - 0.06 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EPR78098.1 - 0.066 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EPR78098.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EPR78098.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 1 0 ABC transporter NB-ARC PF00931.17 EPR78098.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EPR78098.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ThiF PF00899.16 EPR78100.1 - 3.3e-27 94.9 0.7 7e-27 93.9 0.5 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 EPR78100.1 - 9.6e-07 29.0 0.1 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 EPR78100.1 - 3.6e-06 26.9 0.2 0.0001 22.3 0.1 2.3 1 1 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EPR78100.1 - 0.00066 18.8 0.0 0.002 17.3 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EPR78100.1 - 0.0053 16.2 0.0 0.014 14.8 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_18 PF12847.2 EPR78100.1 - 0.015 15.9 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EPR78100.1 - 0.052 13.6 0.9 0.39 10.8 0.4 2.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UBACT PF02134.16 EPR78100.1 - 0.054 13.0 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein AlaDh_PNT_C PF01262.16 EPR78100.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Baculo_11_kDa PF06143.6 EPR78101.1 - 0.078 12.3 0.2 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family HSF_DNA-bind PF00447.12 EPR78102.1 - 1.5e-33 115.0 6.5 3.5e-32 110.6 2.5 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EPR78102.1 - 1.7e-08 34.4 0.1 5.9e-08 32.7 0.2 1.9 2 1 1 3 3 3 1 Response regulator receiver domain DUF3502 PF12010.3 EPR78102.1 - 0.011 15.6 2.0 0.049 13.5 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) DUF3834 PF12916.2 EPR78102.1 - 0.016 14.1 0.6 0.031 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) DUF1685 PF07939.6 EPR78102.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) OKR_DC_1_N PF03709.10 EPR78102.1 - 0.02 14.9 0.1 0.043 13.8 0.1 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain WW PF00397.21 EPR78103.1 - 5.8e-06 26.0 24.6 0.00072 19.3 4.0 2.9 3 0 0 3 3 3 2 WW domain MAGE PF01454.14 EPR78103.1 - 0.0026 17.1 1.7 0.0031 16.8 1.2 1.3 1 0 0 1 1 1 1 MAGE family Prenyltransf PF01255.14 EPR78103.1 - 0.012 14.7 3.9 0.016 14.3 2.7 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase FF PF01846.14 EPR78103.1 - 0.047 13.6 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 FF domain RPAP2_Rtr1 PF04181.8 EPR78103.1 - 4.2 7.5 6.3 2.2 8.4 0.3 2.4 2 0 0 2 2 2 0 Rtr1/RPAP2 family Rad60-SLD PF11976.3 EPR78104.1 - 4.3e-13 48.7 0.0 5.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPR78104.1 - 0.00032 20.0 0.1 0.0004 19.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Bse634I PF07832.6 EPR78104.1 - 0.021 13.9 0.1 0.023 13.8 0.1 1.1 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease DUF916 PF06030.7 EPR78104.1 - 0.052 13.3 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Rad60-SLD_2 PF13881.1 EPR78104.1 - 0.067 13.0 0.1 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like L31 PF09784.4 EPR78104.1 - 0.074 13.1 0.1 0.087 12.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Imm33 PF15580.1 EPR78104.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 33 Paf1 PF03985.8 EPR78105.1 - 2.8e-05 23.0 0.9 2.8e-05 23.0 0.7 1.5 2 0 0 2 2 2 1 Paf1 C-term_anchor PF13461.1 EPR78105.1 - 0.43 11.0 5.6 0.49 10.9 0.2 3.1 3 0 0 3 3 3 0 Cell-wall surface anchor repeat Hexokinase_1 PF00349.16 EPR78106.1 - 6.5e-16 58.2 2.0 1.5e-15 57.1 0.4 2.0 2 0 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 EPR78106.1 - 7.5e-09 35.1 0.2 1.5e-07 30.8 0.1 2.4 1 1 1 2 2 2 1 Hexokinase Enolase_C PF00113.17 EPR78107.1 - 1.8e-91 306.1 1.0 2.3e-91 305.8 0.7 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EPR78107.1 - 4.8e-35 120.3 0.0 9.2e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain Aa_trans PF01490.13 EPR78109.1 - 1.4e-17 63.2 20.7 2e-17 62.8 14.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPR78109.1 - 2.9e-05 23.0 14.9 3.5e-05 22.8 10.3 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family RseC_MucC PF04246.7 EPR78109.1 - 4.1 6.9 9.2 0.14 11.7 1.2 2.0 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SNARE PF05739.14 EPR78110.1 - 0.00022 20.8 7.0 0.00043 19.9 4.9 1.5 1 0 0 1 1 1 1 SNARE domain MSA-2c PF12238.3 EPR78110.1 - 0.058 13.0 8.2 0.015 14.9 3.3 1.7 1 1 1 2 2 2 0 Merozoite surface antigen 2c Atg14 PF10186.4 EPR78110.1 - 0.29 10.0 8.8 0.37 9.6 6.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pox_A_type_inc PF04508.7 EPR78110.1 - 2 8.4 5.4 22 5.1 0.3 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Rad21_Rec8_N PF04825.8 EPR78111.1 - 2.6e-11 43.4 0.3 6.5e-11 42.1 0.2 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPR78111.1 - 8.3e-05 21.6 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein B5 PF03484.10 EPR78111.1 - 0.16 11.7 1.3 0.89 9.4 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain DUF2018 PF09442.5 EPR78111.1 - 1.1 9.8 7.3 0.13 12.7 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) Pkinase PF00069.20 EPR78112.1 - 1.6e-70 237.2 0.1 1.8e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78112.1 - 4.7e-36 124.2 0.0 5.5e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78112.1 - 2.6e-08 33.1 0.0 1.1e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPR78112.1 - 0.00055 19.0 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPR78112.1 - 0.01 15.1 0.4 0.023 14.0 0.2 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EPR78112.1 - 0.043 13.1 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EPR78112.1 - 0.044 12.6 0.0 0.095 11.5 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 PolyA_pol PF01743.15 EPR78113.1 - 3.8e-26 91.7 0.1 9.2e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPR78113.1 - 1.8e-08 33.8 0.1 7.6e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Peptidase_C13 PF01650.13 EPR78114.1 - 3e-17 62.7 0.3 3.6e-17 62.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family 7tm_6 PF02949.15 EPR78114.1 - 0.054 12.3 0.2 0.079 11.8 0.1 1.3 1 0 0 1 1 1 0 7tm Odorant receptor Zn_Tnp_IS1595 PF12760.2 EPR78115.1 - 0.023 14.5 0.9 0.038 13.8 0.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 EPR78115.1 - 0.043 13.6 0.6 0.076 12.8 0.4 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family HypA PF01155.14 EPR78115.1 - 0.086 12.5 1.3 0.18 11.5 0.7 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2296 PF10058.4 EPR78115.1 - 0.37 10.5 3.0 0.71 9.6 2.1 1.4 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) MecA_N PF05223.6 EPR78116.1 - 7.9 6.5 7.9 4.9e+02 0.8 5.5 2.3 1 1 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain Fasciclin PF02469.17 EPR78117.1 - 0.0036 17.3 1.1 0.0054 16.7 0.8 1.3 1 0 0 1 1 1 1 Fasciclin domain Ricin_B_lectin PF00652.17 EPR78118.1 - 0.0094 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF1643 PF07799.7 EPR78119.1 - 0.049 13.3 3.1 0.12 12.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) Terminase_2 PF03592.11 EPR78120.1 - 0.01 16.1 2.0 0.01 16.1 1.4 1.9 2 0 0 2 2 2 0 Terminase small subunit GYF PF02213.11 EPR78120.1 - 0.012 15.1 0.2 0.037 13.6 0.0 1.9 2 0 0 2 2 2 0 GYF domain DUF2118 PF09891.4 EPR78120.1 - 5.1 6.8 9.4 0.68 9.6 2.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) TIM PF00121.13 EPR78121.1 - 3.3e-71 239.2 3.3 3.8e-71 239.0 2.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Mst1_SARAH PF11629.3 EPR78124.1 - 0.034 13.9 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF3552 PF12072.3 EPR78124.1 - 0.65 9.1 10.0 0.038 13.1 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Brix PF04427.13 EPR78125.1 - 4e-13 49.4 3.6 3.9e-12 46.2 2.0 2.0 1 1 1 2 2 2 2 Brix domain Ribosomal_L6e PF01159.14 EPR78126.1 - 0.0022 18.1 1.2 0.053 13.7 0.8 2.2 1 1 0 1 1 1 1 Ribosomal protein L6e DUF1493 PF07377.7 EPR78126.1 - 0.04 13.9 0.9 0.38 10.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Tau95 PF09734.4 EPR78127.1 - 8.6e-16 58.1 12.9 1.1e-14 54.5 9.0 2.1 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit CMS1 PF14617.1 EPR78127.1 - 0.34 9.9 3.2 0.27 10.2 0.1 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Nse4_C PF08743.5 EPR78128.1 - 4.1e-12 45.9 1.5 4.1e-12 45.9 1.1 2.4 2 1 0 2 2 2 1 Nse4 C-terminal Nop PF01798.13 EPR78129.1 - 1.8e-46 157.1 0.2 4e-46 156.0 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOP5NT PF08156.8 EPR78129.1 - 1e-13 51.2 0.1 1e-13 51.2 0.1 4.2 3 1 0 3 3 3 1 NOP5NT (NUC127) domain NOSIC PF08060.8 EPR78129.1 - 1.3e-13 50.5 0.4 4.8e-13 48.6 0.3 2.1 1 0 0 1 1 1 1 NOSIC (NUC001) domain GATA PF00320.22 EPR78130.1 - 1.5e-09 37.0 1.2 3e-09 36.0 0.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 EPR78130.1 - 0.094 12.5 0.9 0.34 10.7 0.6 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EPR78130.1 - 0.81 8.9 3.8 1.1 8.5 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TLD PF07534.11 EPR78131.1 - 4.7e-25 88.1 2.7 6.6e-25 87.7 1.9 1.2 1 0 0 1 1 1 1 TLD ABC2_membrane_3 PF12698.2 EPR78133.1 - 0.00072 18.6 0.2 0.00085 18.4 0.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Flg_hook PF02120.11 EPR78133.1 - 0.037 13.6 0.7 0.068 12.8 0.0 1.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Na_K-ATPase PF00287.13 EPR78133.1 - 0.086 11.6 0.9 0.12 11.1 0.6 1.3 1 1 0 1 1 1 0 Sodium / potassium ATPase beta chain SecY PF00344.15 EPR78133.1 - 0.15 10.9 1.7 0.24 10.3 1.2 1.3 1 0 0 1 1 1 0 SecY translocase PspB PF06667.7 EPR78133.1 - 0.39 10.6 1.8 0.43 10.5 0.3 2.0 2 1 0 2 2 2 0 Phage shock protein B FliS PF02561.9 EPR78133.1 - 0.56 10.0 5.0 0.58 10.0 0.4 2.1 1 1 1 2 2 2 0 Flagellar protein FliS NPBW PF15180.1 EPR78134.1 - 0.71 9.5 4.2 0.27 10.8 0.5 2.0 1 1 1 2 2 2 0 Neuropeptides B and W DUF1675 PF07897.6 EPR78134.1 - 3.4 7.4 29.4 4.4 7.0 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Pkinase PF00069.20 EPR78135.1 - 3e-65 219.9 1.0 3.4e-65 219.7 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78135.1 - 1.3e-34 119.4 0.2 1.8e-34 119.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78135.1 - 9e-08 31.4 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPR78135.1 - 1.6e-05 24.3 0.2 2.4e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EPR78135.1 - 2.4e-05 24.1 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPR78135.1 - 0.00041 19.4 0.0 0.00069 18.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPR78135.1 - 0.0027 16.6 0.6 0.0042 15.9 0.4 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 EPR78135.1 - 0.009 15.5 0.4 0.016 14.7 0.3 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase YchF-GTPase_C PF06071.8 EPR78136.1 - 2.8e-26 91.1 1.6 6.5e-26 89.9 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPR78136.1 - 2.9e-19 69.1 0.1 2.9e-19 69.1 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPR78136.1 - 6.1e-08 32.0 0.8 7.6e-07 28.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_14 PF13173.1 EPR78136.1 - 0.00054 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR78136.1 - 0.0085 16.9 0.6 0.094 13.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain DUF1675 PF07897.6 EPR78136.1 - 0.11 12.2 11.4 0.17 11.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Menin PF05053.8 EPR78136.1 - 0.14 10.3 4.3 0.17 9.9 3.0 1.1 1 0 0 1 1 1 0 Menin Myb_DNA-bind_6 PF13921.1 EPR78138.1 - 7.1e-06 26.0 4.6 7.1e-06 26.0 3.2 3.9 3 1 1 4 4 4 1 Myb-like DNA-binding domain GRAM PF02893.15 EPR78140.1 - 1.3e-05 24.6 0.1 3.3e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.3 EPR78140.1 - 0.059 13.1 0.1 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 DUF1086 PF06461.6 EPR78140.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Glyco_hydr_30_2 PF14587.1 EPR78141.1 - 0.081 11.8 0.2 0.096 11.6 0.2 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 SET PF00856.23 EPR78142.1 - 3.7e-22 79.3 2.4 9.1e-22 78.0 1.7 1.6 1 1 0 1 1 1 1 SET domain Cytidylate_kin PF02224.13 EPR78143.1 - 1.3e-32 112.4 8.5 7e-21 74.2 2.0 2.5 2 1 0 2 2 2 2 Cytidylate kinase AAA_17 PF13207.1 EPR78143.1 - 1.9e-06 28.6 16.3 3e-06 28.0 1.4 3.9 1 1 2 3 3 3 1 AAA domain AAA_18 PF13238.1 EPR78143.1 - 0.00041 20.6 0.4 0.00041 20.6 0.3 4.1 1 1 2 3 3 3 2 AAA domain AAA_33 PF13671.1 EPR78143.1 - 0.0093 15.8 1.2 0.12 12.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain COX6C PF02937.10 EPR78143.1 - 0.37 10.7 2.4 20 5.1 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc LRR_7 PF13504.1 EPR78144.1 - 0.00013 21.6 3.4 1.2 9.6 0.2 4.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EPR78144.1 - 0.023 14.6 9.1 0.67 10.2 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 EPR78144.1 - 0.05 13.6 6.9 3.7 7.9 0.8 4.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 EPR78144.1 - 0.59 9.8 18.2 0.067 12.8 0.9 5.3 3 3 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78144.1 - 3 7.6 15.6 0.41 10.4 1.0 4.7 2 2 2 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 EPR78145.1 - 3.5e-15 55.4 19.5 1.2e-09 37.7 0.3 4.7 3 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EPR78145.1 - 5.2e-12 45.1 28.7 5.8e-05 22.6 0.1 5.1 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78145.1 - 2.4e-07 29.8 26.9 0.042 13.8 0.0 7.9 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR78145.1 - 4e-05 23.1 15.0 3.5 8.2 0.0 6.8 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 EPR78145.1 - 0.00089 19.0 25.9 0.043 13.8 0.3 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_9 PF14580.1 EPR78145.1 - 0.039 13.5 0.6 0.039 13.5 0.4 2.6 2 1 0 2 2 2 0 Leucine-rich repeat UCH PF00443.24 EPR78146.1 - 6.9e-08 31.9 5.6 0.00028 20.0 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78146.1 - 3.8e-05 23.2 5.7 0.0032 16.9 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.6 EPR78146.1 - 0.14 11.6 2.9 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase DUF4381 PF14316.1 EPR78146.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Astro_capsid PF03115.9 EPR78147.1 - 1.5 6.9 6.5 1.7 6.7 4.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2457 PF10446.4 EPR78147.1 - 1.5 7.4 13.4 1.9 7.1 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_4 PF12799.2 EPR78148.1 - 2.8e-12 45.9 21.9 6.9e-09 35.1 4.6 6.1 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78148.1 - 7.2e-10 38.4 9.1 7.2e-10 38.4 6.3 4.9 2 2 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EPR78148.1 - 0.025 14.5 0.9 0.025 14.5 0.6 8.6 7 2 1 8 8 8 0 Leucine Rich Repeat LRR_7 PF13504.1 EPR78148.1 - 0.17 12.1 22.1 4.6 7.8 0.1 7.4 6 1 0 6 6 6 0 Leucine rich repeat DUF440 PF04269.7 EPR78148.1 - 0.25 11.3 4.0 4.2 7.4 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF440 RRM_6 PF14259.1 EPR78149.1 - 2.6e-11 43.3 0.6 0.00013 21.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR78149.1 - 1.9e-05 24.4 2.5 0.015 15.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPR78149.1 - 0.00061 19.3 12.3 0.04 13.5 0.0 4.7 5 2 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPR78149.1 - 0.034 13.9 2.4 2.9 7.7 0.3 2.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EPR78150.1 - 4.9e-39 134.0 0.0 5.4e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78150.1 - 2.2e-15 56.4 0.0 2.8e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78150.1 - 3.8e-11 42.4 0.0 4.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPR78150.1 - 0.0026 16.6 0.1 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 PIP49_C PF12260.3 EPR78150.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 LRR_4 PF12799.2 EPR78151.1 - 1.5e-15 56.3 56.0 6.6e-05 22.4 5.3 8.8 4 3 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78151.1 - 2e-14 51.3 37.7 0.054 13.5 0.2 11.1 10 1 0 10 10 10 6 Leucine Rich Repeat LRR_8 PF13855.1 EPR78151.1 - 1.8e-13 50.0 43.9 1.9e-06 27.5 6.8 6.3 5 1 0 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 EPR78151.1 - 1e-08 33.9 33.7 0.33 11.3 0.1 10.1 10 0 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 EPR78151.1 - 1.8e-07 30.4 42.5 3.4 8.0 0.1 11.2 9 2 2 11 11 11 7 Leucine Rich repeat Pkinase PF00069.20 EPR78152.1 - 0.0033 16.6 0.8 0.0071 15.5 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain TPR_8 PF13181.1 EPR78153.1 - 4.8e-06 25.9 0.5 4.8e-06 25.9 0.3 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPR78153.1 - 2.1e-05 23.9 6.3 0.0016 17.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPR78153.1 - 5.4e-05 23.0 1.4 0.004 17.0 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPR78153.1 - 9e-05 22.0 6.1 0.0013 18.3 0.1 3.1 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EPR78153.1 - 0.0004 20.0 8.5 0.037 13.9 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPR78153.1 - 0.021 14.5 0.1 0.19 11.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 EPR78153.1 - 0.032 14.8 12.5 3.1 8.5 0.1 5.6 6 0 0 6 6 6 0 Sel1 repeat Cpn60_TCP1 PF00118.19 EPR78154.1 - 1.7e-101 340.2 20.2 7.8e-72 242.4 6.3 2.6 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family Rnf-Nqr PF02508.9 EPR78154.1 - 0.063 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein MRP-S23 PF10484.4 EPR78156.1 - 0.056 13.3 0.9 0.13 12.1 0.7 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S23 WD40 PF00400.27 EPR78157.1 - 1.8e-14 52.9 14.8 9e-09 34.8 0.3 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EPR78157.1 - 0.047 13.9 0.0 57 4.1 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Bromo_TP PF07524.8 EPR78158.1 - 6.5e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated Pro_isomerase PF00160.16 EPR78159.1 - 8.5e-45 152.7 3.2 1.1e-44 152.3 2.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2410 PF10307.4 EPR78159.1 - 0.029 13.7 0.5 0.074 12.4 0.5 1.5 2 0 0 2 2 2 0 Hypothetical protein (DUF2410) LRR_1 PF00560.28 EPR78160.1 - 0.00068 19.3 20.1 0.63 10.2 0.1 8.5 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.1 EPR78160.1 - 0.013 15.2 30.5 0.23 11.2 0.4 6.3 3 2 3 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 EPR78160.1 - 0.097 12.3 40.2 1.3 8.7 3.4 6.7 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) PDZ_1 PF12812.2 EPR78160.1 - 0.37 10.7 2.8 0.37 10.7 0.1 2.4 3 0 0 3 3 3 0 PDZ-like domain LRR_6 PF13516.1 EPR78160.1 - 3 8.1 0.0 3 8.1 0.0 8.5 7 2 2 9 9 9 0 Leucine Rich repeat Clat_adaptor_s PF01217.15 EPR78161.1 - 8.3e-16 57.9 8.5 1.5e-15 57.1 5.9 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF3882 PF07066.6 EPR78161.1 - 0.038 13.8 1.3 0.056 13.3 0.5 1.7 1 1 1 2 2 2 0 Lactococcus phage M3 protein LSM PF01423.17 EPR78162.1 - 1.3e-13 50.2 0.2 1.5e-13 50.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain Rad60-SLD PF11976.3 EPR78162.1 - 0.0029 17.2 0.1 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XAP5 PF04921.9 EPR78162.1 - 0.059 12.9 0.1 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator SM-ATX PF14438.1 EPR78162.1 - 0.085 12.7 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3887 PF13026.1 EPR78162.1 - 0.1 12.9 0.4 0.11 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) DUF2870 PF11069.3 EPR78163.1 - 2.1 8.4 14.5 7.4 6.6 1.9 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2870) His_Phos_2 PF00328.17 EPR78164.1 - 0.0089 15.3 0.4 0.021 14.1 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPK2 PF03976.9 EPR78164.1 - 0.022 14.0 0.9 0.046 13.0 0.6 1.5 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) PCI PF01399.22 EPR78164.1 - 0.034 14.4 0.4 0.096 13.0 0.2 2.0 1 1 0 1 1 1 0 PCI domain Pox_Ag35 PF03286.9 EPR78165.1 - 1.6 8.2 6.9 2.3 7.6 4.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PTPlike_phytase PF14566.1 EPR78166.1 - 4.3e-07 30.0 1.4 3.3e-06 27.2 1.0 2.3 1 1 0 1 1 1 1 Inositol hexakisphosphate Apc3 PF12895.2 EPR78167.1 - 3.2e-08 33.6 19.4 1.7e-05 24.8 4.5 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EPR78167.1 - 9.2e-06 25.9 3.7 0.0071 16.6 0.7 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPR78167.1 - 0.0049 16.6 12.4 0.2 11.6 0.6 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EPR78167.1 - 0.017 14.5 5.4 0.06 12.8 0.6 2.3 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_8 PF13181.1 EPR78167.1 - 0.39 10.5 15.1 0.3 10.9 2.5 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPR78167.1 - 0.42 10.2 14.3 3.8 7.2 0.4 4.1 3 1 1 4 4 4 0 TPR repeat TPR_12 PF13424.1 EPR78167.1 - 0.53 10.2 5.1 11 6.0 0.2 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat EIF_2_alpha PF07541.7 EPR78167.1 - 1.4 8.6 9.5 0.3 10.8 0.9 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit TPR_1 PF00515.23 EPR78167.1 - 3.3 7.4 23.4 0.36 10.5 1.9 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPR78167.1 - 6.7 6.6 11.1 5.2 7.0 1.0 3.5 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MAD PF05557.8 EPR78168.1 - 3.6e-09 35.3 10.3 7.5e-09 34.2 7.2 1.4 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF2353 PF09789.4 EPR78168.1 - 0.0011 18.2 5.2 0.0015 17.8 3.6 1.2 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.3 EPR78168.1 - 0.0019 18.1 9.4 0.003 17.4 6.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3552 PF12072.3 EPR78168.1 - 0.0028 16.9 8.5 0.004 16.4 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) IFT57 PF10498.4 EPR78168.1 - 0.0072 15.1 11.5 0.0099 14.6 8.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF724 PF05266.9 EPR78168.1 - 0.008 15.8 4.6 0.011 15.3 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Inhibitor_I9 PF05922.11 EPR78168.1 - 0.015 15.8 0.7 0.027 15.0 0.5 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 CASP_C PF08172.7 EPR78168.1 - 0.015 14.3 4.1 0.02 13.9 2.9 1.2 1 0 0 1 1 1 0 CASP C terminal IncA PF04156.9 EPR78168.1 - 0.017 14.7 4.8 0.023 14.2 3.4 1.2 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EPR78168.1 - 0.017 15.3 17.6 0.051 13.8 11.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EPR78168.1 - 0.02 12.7 4.5 0.019 12.8 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EPR78168.1 - 0.03 14.0 7.9 0.043 13.4 5.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 POT1 PF02765.12 EPR78168.1 - 0.035 14.0 1.2 0.048 13.5 0.3 1.6 1 1 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 DivIC PF04977.10 EPR78168.1 - 0.044 13.2 15.0 0.032 13.7 3.9 2.5 1 1 1 2 2 2 0 Septum formation initiator Tropomyosin_1 PF12718.2 EPR78168.1 - 0.081 12.7 11.0 0.13 12.1 7.6 1.3 1 0 0 1 1 1 0 Tropomyosin like Hormone_1 PF00103.15 EPR78168.1 - 0.15 11.4 3.9 0.22 10.8 2.7 1.4 1 0 0 1 1 1 0 Somatotropin hormone family bZIP_1 PF00170.16 EPR78168.1 - 0.16 11.9 15.7 1.1 9.2 5.9 2.6 1 1 1 2 2 2 0 bZIP transcription factor Nup54 PF13874.1 EPR78168.1 - 0.17 11.5 4.5 0.27 10.9 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 EPR78168.1 - 0.18 12.1 7.4 0.33 11.2 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EPR78168.1 - 0.18 10.7 6.0 0.24 10.2 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FadA PF09403.5 EPR78168.1 - 0.28 11.2 11.8 3 7.8 7.7 2.6 1 1 1 2 2 2 0 Adhesion protein FadA LMBR1 PF04791.11 EPR78168.1 - 0.38 9.2 3.2 0.5 8.8 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.3 EPR78168.1 - 0.44 9.7 5.5 0.61 9.2 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_2 PF07716.10 EPR78168.1 - 0.51 10.2 15.4 0.27 11.0 3.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Ax_dynein_light PF10211.4 EPR78168.1 - 0.75 9.5 11.0 1.6 8.5 7.6 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain Jnk-SapK_ap_N PF09744.4 EPR78168.1 - 0.9 9.5 11.1 1.4 8.8 7.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.6 EPR78168.1 - 4.6 7.2 11.2 11 5.9 3.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ly49 PF08391.5 EPR78168.1 - 5.5 7.1 9.1 9.6 6.3 6.3 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region hDGE_amylase PF14701.1 EPR78170.1 - 0.0064 15.4 5.7 0.0073 15.2 4.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme UCH PF00443.24 EPR78170.1 - 0.34 9.9 5.8 0.47 9.5 4.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase MitMem_reg PF13012.1 EPR78170.1 - 6.1 6.9 11.5 1.2 9.2 1.5 2.6 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Proteasome PF00227.21 EPR78171.1 - 3.3e-35 121.1 0.0 4.6e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPR78171.1 - 7.9e-09 34.6 0.0 1.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-DBF PF07535.7 EPR78172.1 - 5.8e-17 61.0 1.8 1.3e-16 59.9 1.3 1.6 1 0 0 1 1 1 1 DBF zinc finger NotI PF12183.3 EPR78172.1 - 0.069 12.2 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI Med6 PF04934.9 EPR78173.1 - 1.7e-34 118.3 3.3 2.2e-34 118.0 2.3 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component AAA_11 PF13086.1 EPR78174.1 - 0.15 11.6 4.1 0.16 11.4 2.9 1.1 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.12 EPR78177.1 - 0.001 18.5 10.3 0.036 13.5 4.0 2.1 2 0 0 2 2 2 2 Yip1 domain TaqI_C PF12950.2 EPR78177.1 - 0.018 14.8 2.4 0.034 13.9 1.6 1.6 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain ABC2_membrane_4 PF12730.2 EPR78177.1 - 0.11 11.6 23.9 0.028 13.5 9.9 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein CENP-T PF15511.1 EPR78178.1 - 6.7 5.8 17.6 8 5.5 12.2 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Exo_endo_phos PF03372.18 EPR78179.1 - 3.5e-17 63.1 0.0 1.2e-16 61.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_7 PF13241.1 EPR78179.1 - 0.11 12.7 0.0 2.1 8.6 0.0 2.4 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF605 PF04652.11 EPR78180.1 - 2.9 7.1 28.0 3.3 7.0 19.4 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EPR78180.1 - 8 4.5 23.3 9.1 4.3 16.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Shisa PF13908.1 EPR78181.1 - 0.01 16.0 0.1 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SpoIIIAH PF12685.2 EPR78181.1 - 0.016 14.7 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein HAND PF09110.6 EPR78181.1 - 0.016 15.5 1.1 0.018 15.4 0.3 1.6 1 1 0 1 1 1 0 HAND DUF1378 PF07125.6 EPR78181.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Baculo_11_kDa PF06143.6 EPR78181.1 - 0.056 12.8 0.9 0.094 12.0 0.4 1.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Rax2 PF12768.2 EPR78181.1 - 0.081 12.1 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.1 EPR78181.1 - 0.098 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family NEL PF14496.1 EPR78182.1 - 0.033 13.4 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting DUF1256 PF06866.6 EPR78182.1 - 0.085 12.0 0.1 0.085 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) Arv1 PF04161.8 EPR78182.1 - 0.16 11.8 2.6 0.12 12.3 0.7 1.4 2 0 0 2 2 2 0 Arv1-like family UCH PF00443.24 EPR78183.1 - 2.5e-08 33.3 11.1 0.00033 19.8 0.7 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.15 EPR78183.1 - 2.4 8.4 9.2 12 6.2 0.2 4.1 4 0 0 4 4 4 0 Putative cell wall binding repeat DUF3591 PF12157.3 EPR78186.1 - 6.2e-101 338.0 0.1 6.2e-101 338.0 0.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EPR78186.1 - 1.6e-19 69.6 0.3 1.6e-19 69.6 0.2 3.3 3 0 0 3 3 3 1 Bromodomain zf-CCHC_6 PF15288.1 EPR78186.1 - 2.2e-05 24.0 2.6 6e-05 22.6 1.8 1.8 1 0 0 1 1 1 1 Zinc knuckle Ribonuc_red_lgC PF02867.10 EPR78187.1 - 9.3e-140 466.7 2.8 1.2e-139 466.3 1.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EPR78187.1 - 1.6e-14 53.4 0.0 4.4e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain LSM PF01423.17 EPR78188.1 - 7.3e-12 44.6 1.7 7.3e-12 44.6 1.2 1.5 1 1 1 2 2 2 1 LSM domain SM-ATX PF14438.1 EPR78188.1 - 0.025 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DWNN PF08783.6 EPR78188.1 - 0.19 11.7 1.3 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 DWNN domain LRR_4 PF12799.2 EPR78189.1 - 1.9e-26 91.1 66.9 2.3e-07 30.2 0.7 12.1 9 3 3 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78189.1 - 1e-19 70.0 64.3 1.3e-08 34.4 1.0 9.7 5 3 6 11 11 11 8 Leucine rich repeat LRR_1 PF00560.28 EPR78189.1 - 1.2e-07 30.7 57.5 1 9.6 0.2 15.6 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_8 PF13855.1 EPR78190.1 - 1.4e-25 88.8 65.6 1.1e-07 31.4 1.9 7.9 4 3 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EPR78190.1 - 9.7e-25 85.7 76.4 7.4e-06 25.4 0.7 9.9 6 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78190.1 - 7.2e-08 31.4 68.2 0.026 14.4 0.0 15.3 14 1 1 15 15 15 6 Leucine Rich Repeat LRR_7 PF13504.1 EPR78190.1 - 3.6e-05 23.2 44.6 3 8.4 0.0 14.0 14 1 1 15 15 15 3 Leucine rich repeat Sedlin_N PF04628.8 EPR78192.1 - 0.0011 18.8 1.3 0.0019 18.0 0.9 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Leuk-A4-hydro_C PF09127.6 EPR78192.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal LRR_4 PF12799.2 EPR78195.1 - 5e-35 118.5 73.4 1.3e-07 31.0 1.8 9.5 7 2 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78195.1 - 1.2e-28 98.5 70.9 2.1e-09 37.0 3.4 8.8 5 2 2 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EPR78195.1 - 5.9e-13 46.9 66.6 0.17 12.0 0.4 15.5 14 2 1 15 15 15 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR78195.1 - 1.3e-08 33.6 45.0 0.67 10.3 0.1 14.1 14 0 0 14 14 14 3 Leucine rich repeat LRR_6 PF13516.1 EPR78195.1 - 0.041 13.9 65.7 0.37 11.0 0.2 13.6 13 1 1 14 14 14 0 Leucine Rich repeat HEAT_2 PF13646.1 EPR78196.1 - 4.6e-26 90.9 0.0 4.3e-12 46.1 0.0 3.1 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EPR78196.1 - 8.1e-16 56.8 0.0 0.0081 16.5 0.0 5.0 5 0 0 5 5 5 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EPR78196.1 - 7.9e-07 29.3 0.0 0.13 12.8 0.0 4.0 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EPR78196.1 - 6.7e-06 25.7 0.0 4.9 7.4 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat PRA1 PF03208.14 EPR78197.1 - 8.9e-11 41.3 0.5 1.2e-10 40.9 0.3 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF3882 PF07066.6 EPR78197.1 - 0.018 14.8 0.9 0.023 14.5 0.6 1.1 1 0 0 1 1 1 0 Lactococcus phage M3 protein TMPIT PF07851.8 EPR78197.1 - 0.57 9.1 3.9 0.48 9.4 1.9 1.4 1 1 0 1 1 1 0 TMPIT-like protein LSM PF01423.17 EPR78198.1 - 3.2e-06 26.5 9.5 1.1e-05 24.8 6.6 1.8 1 1 0 1 1 1 1 LSM domain MSC PF09402.5 EPR78199.1 - 1.7e-11 43.4 1.7 2.2e-11 43.0 1.2 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain CoA_binding_3 PF13727.1 EPR78199.1 - 0.0052 16.6 0.2 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 CoA-binding domain Spc97_Spc98 PF04130.8 EPR78200.1 - 2.4e-37 128.5 33.0 2.3e-35 121.9 22.8 2.3 1 1 0 1 1 1 1 Spc97 / Spc98 family SNAP PF14938.1 EPR78201.1 - 2.5e-12 46.5 7.5 4.4e-12 45.7 5.2 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EPR78201.1 - 4.8e-05 23.2 2.6 0.013 15.3 0.4 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPR78201.1 - 0.013 15.1 3.3 0.75 9.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EPR78201.1 - 0.13 12.4 3.8 4.4 7.5 1.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EPR78201.1 - 0.36 10.5 14.5 2.6 7.8 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPR78201.1 - 1.1 8.9 9.8 8.4 6.1 0.3 3.4 1 1 1 2 2 2 0 TPR repeat RELT PF12606.3 EPR78202.1 - 3.8 6.7 8.0 9.8 5.4 2.7 2.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Enkurin PF13864.1 EPR78203.1 - 0.019 15.1 1.5 0.019 15.1 1.0 2.5 1 1 1 2 2 2 0 Calmodulin-binding Hormone_recep PF00104.25 EPR78203.1 - 0.38 9.8 7.1 0.76 8.8 0.7 2.4 2 1 0 2 2 2 0 Ligand-binding domain of nuclear hormone receptor DnaJ PF00226.26 EPR78204.1 - 2.3e-11 43.2 2.5 1.9e-10 40.3 1.7 2.4 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.11 EPR78204.1 - 1.1e-08 34.6 1.8 1.1e-08 34.6 1.3 2.0 2 1 0 2 2 2 1 Sec63 Brl domain DUF4234 PF14018.1 EPR78204.1 - 8 6.2 8.2 2.4 7.9 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) UCH PF00443.24 EPR78205.1 - 2.8e-11 43.0 3.5 4.9e-11 42.2 2.4 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78205.1 - 0.00023 20.6 0.5 0.00035 20.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EPR78206.1 - 1.9e-08 33.7 0.2 3.1e-08 33.0 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78206.1 - 0.0067 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ATP-synt_8 PF00895.15 EPR78206.1 - 0.23 11.6 0.9 0.49 10.6 0.6 1.5 1 0 0 1 1 1 0 ATP synthase protein 8 ACT_3 PF10000.4 EPR78207.1 - 0.0017 18.0 3.2 3.8 7.3 0.0 3.3 1 1 2 3 3 3 3 ACT domain SynMuv_product PF06047.6 EPR78207.1 - 0.02 14.6 0.0 0.068 12.8 0.0 1.9 1 0 0 1 1 1 0 Ras-induced vulval development antagonist U5_2-snRNA_bdg PF10597.4 EPR78211.1 - 8.4e-29 99.9 3.4 5.3e-17 61.6 0.0 2.2 1 1 0 2 2 2 2 U5-snRNA binding site 2 of PrP8 SMN PF06003.7 EPR78211.1 - 9.3e-05 21.6 1.0 9.9e-05 21.5 0.2 1.3 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) COX6C PF02937.10 EPR78212.1 - 0.075 12.9 0.6 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc TPT PF03151.11 EPR78212.1 - 0.075 12.6 7.8 0.12 11.9 5.4 1.3 1 1 0 1 1 1 0 Triose-phosphate Transporter family 7TMR-DISM_7TM PF07695.6 EPR78213.1 - 1.1 8.9 26.9 1.1 8.8 18.6 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling BTP PF05232.7 EPR78213.1 - 7.6 6.3 15.9 0.77 9.5 3.7 2.4 1 1 1 2 2 2 0 Bacterial Transmembrane Pair family ThiW PF09512.5 EPR78214.1 - 0.0048 16.7 0.5 0.0099 15.7 0.3 1.5 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) 5TM-5TMR_LYT PF07694.7 EPR78214.1 - 0.015 14.6 0.9 0.015 14.6 0.6 2.2 1 1 1 2 2 2 0 5TMR of 5TMR-LYT YfzA PF14118.1 EPR78214.1 - 0.16 12.0 4.7 0.2 11.7 2.4 1.9 1 1 0 1 1 1 0 YfzA-like protein Connexin_CCC PF10582.4 EPR78214.1 - 0.17 11.6 2.2 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain EamA PF00892.15 EPR78214.1 - 0.66 10.0 11.5 0.57 10.2 5.7 2.0 1 1 1 2 2 2 0 EamA-like transporter family DUF751 PF05421.6 EPR78214.1 - 7.6 6.9 11.9 2.5 8.4 1.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF751) DUF3890 PF13029.1 EPR78215.1 - 0.014 15.4 1.5 0.038 14.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) LAGLIDADG_1 PF00961.14 EPR78215.1 - 1.6 9.3 8.8 3.8 8.1 0.9 2.5 1 1 1 2 2 2 0 LAGLIDADG endonuclease LAGLIDADG_1 PF00961.14 EPR78216.1 - 0.068 13.7 3.1 0.12 12.9 2.1 1.5 1 0 0 1 1 1 0 LAGLIDADG endonuclease ARL2_Bind_BART PF11527.3 EPR78216.1 - 0.14 11.9 1.9 1 9.1 0.3 2.4 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Pollen_allerg_2 PF01620.11 EPR78218.1 - 3.2 8.0 4.2 4.8 7.4 2.2 1.8 1 1 1 2 2 2 0 Ribonuclease (pollen allergen) Adap_comp_sub PF00928.16 EPR78219.1 - 2.2e-14 53.1 7.8 3e-14 52.7 5.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DASH_Dad4 PF08650.5 EPR78219.1 - 0.16 11.8 1.9 0.4 10.6 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 TFIID-18kDa PF02269.11 EPR78220.1 - 3.9e-22 77.8 1.4 4.7e-22 77.6 1.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Asn_synthase PF00733.16 EPR78221.1 - 1.1e-29 103.7 0.0 7.3e-29 101.0 0.0 1.9 1 1 0 1 1 1 1 Asparagine synthase IMCp PF12314.3 EPR78221.1 - 0.049 13.7 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Inner membrane complex protein Ribonuclease_3 PF00636.21 EPR78224.1 - 4.7e-26 91.4 3.2 4e-16 59.4 0.2 5.2 5 1 0 5 5 5 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPR78224.1 - 5.3e-23 81.3 7.5 6.1e-08 32.6 0.1 4.8 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EPR78224.1 - 0.0023 17.6 0.0 0.0061 16.3 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Fijivirus_P9-2 PF06837.6 EPR78225.1 - 0.033 13.3 0.3 0.04 13.0 0.2 1.2 1 0 0 1 1 1 0 Fijivirus P9-2 protein UBA_3 PF09288.5 EPR78225.1 - 0.056 13.0 1.0 0.056 13.0 0.7 1.8 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Spore_III_AF PF09581.5 EPR78225.1 - 0.64 9.8 5.5 0.98 9.2 3.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) ERCC4 PF02732.10 EPR78226.1 - 7.6e-23 80.8 3.1 1.9e-22 79.5 0.8 2.4 2 0 0 2 2 2 1 ERCC4 domain HHH PF00633.18 EPR78226.1 - 0.011 15.3 0.0 0.04 13.6 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.2 EPR78226.1 - 0.053 13.4 0.0 4.8 7.1 0.0 3.2 3 1 0 3 3 3 0 Helix-hairpin-helix motif EXS PF03124.9 EPR78227.1 - 4.8e-07 29.1 10.0 5.9e-07 28.8 6.9 1.1 1 0 0 1 1 1 1 EXS family MARVEL PF01284.18 EPR78227.1 - 7.4 6.3 6.6 10 5.9 4.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain EXS PF03124.9 EPR78228.1 - 0.00038 19.5 10.9 0.00077 18.5 7.5 1.5 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EPR78228.1 - 0.98 9.1 28.4 0.11 12.2 0.8 2.3 2 0 0 2 2 2 0 SPX domain MutS_III PF05192.13 EPR78229.1 - 4.9e-15 55.8 0.5 7.4e-15 55.2 0.4 1.3 1 0 0 1 1 1 1 MutS domain III Pkinase PF00069.20 EPR78231.1 - 3.5e-58 196.8 4.2 3.9e-58 196.6 2.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78231.1 - 3.3e-41 141.0 0.4 4.2e-41 140.7 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78231.1 - 7.1e-06 25.1 0.0 0.0042 16.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPR78231.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L22e PF01776.12 EPR78232.1 - 5.5e-26 90.7 0.9 6.1e-26 90.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family LRR_4 PF12799.2 EPR78233.1 - 1.2e-20 72.7 43.5 1.9e-08 33.7 1.9 7.4 2 2 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78233.1 - 2.2e-20 72.1 40.9 1.7e-06 27.6 3.2 4.8 2 2 3 5 5 5 5 Leucine rich repeat LRR_7 PF13504.1 EPR78233.1 - 2e-12 45.1 16.0 0.54 10.6 0.0 9.3 10 0 0 10 10 10 4 Leucine rich repeat LRR_1 PF00560.28 EPR78233.1 - 1.1e-10 39.9 46.6 0.015 15.2 0.1 10.0 8 1 2 10 10 10 6 Leucine Rich Repeat LRR_6 PF13516.1 EPR78233.1 - 1.7e-07 30.5 31.3 0.49 10.6 0.5 9.4 7 2 2 9 9 9 4 Leucine Rich repeat LRR_9 PF14580.1 EPR78233.1 - 0.24 10.9 11.0 0.22 11.0 0.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.2 EPR78234.1 - 1.7e-08 33.8 12.4 3.7e-06 26.4 2.3 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78234.1 - 5.3e-05 22.8 2.8 5.3e-05 22.8 1.9 2.7 2 1 1 3 3 3 1 Leucine rich repeat FGGY_N PF00370.16 EPR78234.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain LRR_7 PF13504.1 EPR78234.1 - 0.033 14.3 1.2 6.5 7.4 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat UCH PF00443.24 EPR78234.1 - 0.2 10.7 3.8 0.78 8.7 2.7 1.9 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase LRR_6 PF13516.1 EPR78234.1 - 0.25 11.5 0.1 0.25 11.5 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich repeat DUF1904 PF08921.6 EPR78234.1 - 0.26 11.3 2.7 2.4 8.2 1.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1904) LRR_1 PF00560.28 EPR78234.1 - 3.6 7.9 21.9 0.39 10.9 0.2 5.4 7 0 0 7 7 7 0 Leucine Rich Repeat DUF4030 PF13222.1 EPR78237.1 - 0.00072 19.2 2.1 0.00072 19.2 1.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4030) Trehalase PF01204.13 EPR78238.1 - 1.4e-129 433.0 1.7 2e-129 432.5 1.2 1.2 1 0 0 1 1 1 1 Trehalase LRR_4 PF12799.2 EPR78239.1 - 5.6e-25 86.4 85.9 6.8e-06 25.5 0.4 9.6 4 2 5 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78239.1 - 7.6e-21 73.6 67.7 6.1e-06 25.8 3.7 7.7 3 3 3 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EPR78239.1 - 5.4e-13 47.0 84.7 0.059 13.4 1.0 15.2 16 0 0 16 16 16 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR78239.1 - 4.3e-07 29.0 50.5 0.26 11.6 0.1 13.5 14 0 0 14 14 14 4 Leucine rich repeat LRR_6 PF13516.1 EPR78239.1 - 0.02 14.8 1.2 0.02 14.8 0.8 12.3 13 0 0 13 13 13 0 Leucine Rich repeat IF3_C PF00707.17 EPR78239.1 - 0.039 13.6 0.1 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-3, C-terminal domain TFIIE_beta PF02186.10 EPR78240.1 - 2.9e-06 27.1 0.8 2.9e-06 27.1 0.5 2.3 2 0 0 2 2 2 1 TFIIE beta subunit core domain DUF770 PF05591.7 EPR78240.1 - 0.002 17.7 0.2 0.0036 16.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF770) HTH_24 PF13412.1 EPR78240.1 - 0.0033 16.7 0.1 0.65 9.4 0.0 3.1 2 1 1 3 3 3 2 Winged helix-turn-helix DNA-binding Tbf5 PF06331.7 EPR78240.1 - 0.0051 16.5 0.2 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF2205 PF10224.4 EPR78240.1 - 0.0086 15.6 2.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) HHH_2 PF12826.2 EPR78241.1 - 0.00014 21.7 0.1 0.35 10.7 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EPR78241.1 - 0.0083 16.2 0.4 0.022 14.9 0.3 1.8 1 1 0 1 1 1 1 Helix-hairpin-helix domain TraP PF07296.6 EPR78241.1 - 0.23 10.3 1.6 0.28 10.1 0.1 1.9 2 0 0 2 2 2 0 TraP protein 5_3_exonuc PF01367.15 EPR78241.1 - 2.7 8.3 10.4 0.51 10.5 0.2 3.5 3 2 1 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold Caenor_Her-1 PF09232.5 EPR78242.1 - 0.047 13.7 1.5 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Caenorhabditis elegans Her-1 DUF2591 PF10765.4 EPR78243.1 - 0.16 12.1 4.6 0.19 11.9 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2591) UCH PF00443.24 EPR78244.1 - 9.7e-40 136.3 11.7 1.8e-39 135.5 8.1 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78244.1 - 7.6e-10 38.7 14.7 3.4e-08 33.2 10.2 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MGC-24 PF05283.6 EPR78244.1 - 0.27 10.9 2.7 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) rpo30_N PF12410.3 EPR78244.1 - 1 9.0 5.9 0.27 10.8 1.5 1.9 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Pkinase PF00069.20 EPR78246.1 - 2.5e-42 144.8 0.1 4.1e-42 144.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78246.1 - 6.6e-32 110.6 0.1 9.4e-32 110.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78246.1 - 2.9e-08 33.0 0.0 4.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPR78246.1 - 1.7e-05 24.2 0.2 4.3e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPR78246.1 - 0.0003 19.9 0.0 0.00052 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR78246.1 - 0.00031 20.5 0.0 0.0016 18.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPR78246.1 - 0.013 14.3 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 PaRep2a PF07903.6 EPR78246.1 - 0.14 11.7 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 PaRep2a protein Pkinase PF00069.20 EPR78247.1 - 1.3e-35 122.8 0.6 2.3e-35 122.0 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78247.1 - 5.7e-23 81.3 0.5 1e-22 80.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78247.1 - 1.1e-05 24.5 0.0 1.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPR78247.1 - 0.00033 19.7 0.1 0.0013 17.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPR78247.1 - 0.00067 19.0 0.3 0.00067 19.0 0.2 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EPR78248.1 - 3.3e-33 114.9 2.0 4.7e-33 114.4 1.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78248.1 - 1.7e-24 86.2 0.1 2.7e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPR78248.1 - 6.7e-05 22.0 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPR78248.1 - 8.4e-05 21.5 1.7 0.00013 20.9 1.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EPR78248.1 - 0.00025 20.4 0.4 0.0007 18.9 0.3 1.8 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EPR78248.1 - 0.00052 19.0 0.0 0.0013 17.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPR78248.1 - 0.00053 19.7 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-CHY PF05495.7 EPR78249.1 - 1.7e-14 53.7 23.2 1.7e-14 53.7 16.1 4.5 2 1 0 3 3 3 1 CHY zinc finger zinc_ribbon_6 PF14599.1 EPR78249.1 - 5.6e-09 35.6 8.2 5.6e-09 35.6 5.7 4.9 3 2 3 6 6 6 1 Zinc-ribbon zf-RING_2 PF13639.1 EPR78249.1 - 3.2e-07 30.0 5.3 3.2e-07 30.0 3.6 5.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPR78249.1 - 3.2e-06 27.0 6.8 3.2e-06 27.0 4.7 5.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR78249.1 - 5.5e-05 22.7 4.6 5.5e-05 22.7 3.2 6.1 2 2 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SET PF00856.23 EPR78250.1 - 2.3e-20 73.5 2.2 8.6e-20 71.6 1.5 2.0 1 1 0 1 1 1 1 SET domain PHD PF00628.24 EPR78250.1 - 0.00019 21.0 9.6 0.00019 21.0 6.6 4.2 5 0 0 5 5 5 2 PHD-finger ATP_bind_3 PF01171.15 EPR78251.1 - 8e-19 67.8 0.1 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EPR78251.1 - 0.00062 20.0 0.2 0.0029 17.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) PAPS_reduct PF01507.14 EPR78251.1 - 0.0011 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF4145 PF13643.1 EPR78251.1 - 0.033 14.0 1.0 0.079 12.8 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) DZR PF12773.2 EPR78251.1 - 0.88 9.4 10.8 1.9 8.3 0.5 3.2 3 0 0 3 3 3 0 Double zinc ribbon GATA PF00320.22 EPR78251.1 - 1.1 8.6 6.7 1.9 7.8 0.1 3.0 3 0 0 3 3 3 0 GATA zinc finger Acetyltransf_1 PF00583.19 EPR78252.1 - 8.9e-10 38.4 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPR78252.1 - 3.2e-05 23.9 0.1 5.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPR78252.1 - 0.00075 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPR78252.1 - 0.062 13.0 0.1 0.18 11.6 0.1 1.7 1 1 0 1 1 1 0 FR47-like protein ATP_bind_4 PF01902.12 EPR78253.1 - 4.1e-41 140.7 3.1 1.3e-40 139.1 2.1 1.6 1 1 0 1 1 1 1 ATP-binding region Sua5_yciO_yrdC PF01300.13 EPR78253.1 - 0.0087 15.3 0.0 0.021 14.0 0.0 1.5 1 1 1 2 2 2 1 Telomere recombination SPATA24 PF15175.1 EPR78255.1 - 0.01 15.5 2.3 0.013 15.1 1.6 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Ima1_N PF09779.4 EPR78255.1 - 0.057 13.9 8.3 0.067 13.6 5.7 1.1 1 0 0 1 1 1 0 Ima1 N-terminal domain PolC_DP2 PF03833.8 EPR78255.1 - 0.07 10.7 1.1 0.073 10.7 0.8 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD_2 PF13831.1 EPR78255.1 - 0.46 9.8 0.2 0.46 9.8 0.1 3.6 4 0 0 4 4 4 0 PHD-finger zinc-ribbons_6 PF07191.7 EPR78255.1 - 1.1 9.0 12.9 0.31 10.8 2.7 2.5 2 1 0 2 2 2 0 zinc-ribbons FYVE PF01363.16 EPR78255.1 - 1.8 8.5 12.6 33 4.4 8.7 2.4 1 1 0 1 1 1 0 FYVE zinc finger PHD PF00628.24 EPR78255.1 - 2.1 8.1 15.4 6.3 6.5 0.3 2.8 2 1 0 2 2 2 0 PHD-finger HypA PF01155.14 EPR78255.1 - 3.4 7.3 6.4 4.7 6.9 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF3317 PF11779.3 EPR78256.1 - 0.1 12.0 0.2 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Orthopox_A49R PF06489.6 EPR78257.1 - 0.073 13.0 1.5 0.21 11.5 1.1 1.6 1 1 1 2 2 2 0 Orthopoxvirus A49R protein DUF3752 PF12572.3 EPR78257.1 - 0.076 13.1 0.4 0.098 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) DNA_mis_repair PF01119.14 EPR78258.1 - 3.2e-06 26.5 3.7 1.2e-05 24.7 2.6 2.1 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EPR78258.1 - 9.2e-05 22.1 2.4 0.0001 21.9 0.5 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fun_ATP-synt_8 PF05933.8 EPR78260.1 - 1.2 9.2 7.1 0.29 11.2 1.7 2.3 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Secretin_N_2 PF07655.8 EPR78260.1 - 2.8 8.3 6.1 1.3 9.4 0.3 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Glyco_hydro_65m PF03632.10 EPR78261.1 - 0.16 10.5 3.7 0.22 10.1 2.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain FTCD_C PF04961.7 EPR78261.1 - 1.2 8.5 6.4 0.11 11.8 1.1 1.7 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase AAA_22 PF13401.1 EPR78263.1 - 1e-10 41.8 3.1 1.6e-09 37.9 2.1 2.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPR78263.1 - 2.6e-06 27.3 3.2 2.6e-06 27.3 2.2 1.8 1 1 1 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EPR78263.1 - 3.3e-05 23.9 0.0 0.00018 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 EPR78263.1 - 0.017 14.6 0.1 0.017 14.6 0.1 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EPR78263.1 - 0.037 14.2 12.4 0.46 10.6 7.4 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPR78263.1 - 0.048 13.4 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EPR78263.1 - 0.053 13.2 1.1 7.1 6.3 1.2 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPR78263.1 - 0.31 10.9 0.1 0.31 10.9 0.1 3.6 2 2 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EPR78263.1 - 2.2 8.5 19.2 18 5.6 8.0 3.6 2 1 0 2 2 2 0 AAA domain WD40 PF00400.27 EPR78264.1 - 2.3e-19 68.4 0.3 1.4e-06 27.9 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Sof1 PF04158.9 EPR78264.1 - 1.5e-14 53.7 17.5 1.5e-14 53.7 12.1 2.0 2 0 0 2 2 2 1 Sof1-like domain BBS2_Mid PF14783.1 EPR78264.1 - 0.046 13.5 0.7 19 5.0 0.0 3.3 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF1493 PF07377.7 EPR78264.1 - 0.14 12.2 3.9 0.18 11.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) EMP24_GP25L PF01105.19 EPR78266.1 - 0.00029 20.6 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD WhiA_N PF10298.4 EPR78266.1 - 0.053 13.3 0.7 0.13 12.0 0.5 1.6 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain LRR_4 PF12799.2 EPR78267.1 - 3.1e-28 96.8 100.5 1e-05 24.9 2.3 12.7 8 3 6 14 14 14 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78267.1 - 8.5e-25 86.2 82.0 7.7e-07 28.7 0.7 9.6 5 3 7 12 12 12 9 Leucine rich repeat LRR_1 PF00560.28 EPR78267.1 - 5.1e-14 50.1 77.6 0.16 12.1 0.1 17.5 18 0 0 18 18 18 12 Leucine Rich Repeat LRR_7 PF13504.1 EPR78267.1 - 0.0038 17.1 54.4 1.4 9.4 0.2 14.3 16 1 0 16 16 16 4 Leucine rich repeat Pkinase PF00069.20 EPR78268.1 - 3.8e-34 118.0 0.7 1.2e-33 116.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78268.1 - 6.4e-19 68.0 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78268.1 - 8.8e-07 28.1 0.0 1.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like GRP PF07172.6 EPR78268.1 - 0.021 15.2 0.1 0.047 14.1 0.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family APH PF01636.18 EPR78268.1 - 0.026 14.2 0.0 0.08 12.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family EcKinase PF02958.15 EPR78268.1 - 0.042 13.0 0.8 0.07 12.2 0.1 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase YqbF PF14553.1 EPR78270.1 - 0.12 12.0 6.9 0.076 12.6 1.8 3.0 3 0 0 3 3 3 0 YqbF, hypothetical protein domain S_locus_glycop PF00954.15 EPR78271.1 - 0.72 10.1 4.2 0.59 10.4 0.7 2.5 1 1 1 2 2 2 0 S-locus glycoprotein family Eapp_C PF10238.4 EPR78272.1 - 0.24 11.3 7.2 0.37 10.6 5.0 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Cation_ATPase_N PF00690.21 EPR78273.1 - 3.1e-06 26.5 0.3 8.9e-06 25.0 0.1 1.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Helicase_C_2 PF13307.1 EPR78274.1 - 4.9e-46 156.7 0.7 1.3e-45 155.3 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EPR78274.1 - 3.4e-44 150.2 9.5 6.9e-44 149.3 4.4 2.5 2 0 0 2 2 2 1 DEAD_2 DUF1227 PF06777.6 EPR78274.1 - 5.1e-28 97.6 3.7 1.3e-27 96.2 2.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD PF00270.24 EPR78274.1 - 1.5e-07 31.0 0.5 0.0045 16.4 0.0 2.9 2 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EPR78274.1 - 0.00013 21.8 5.7 0.09 12.5 0.0 3.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPR78274.1 - 0.00071 18.4 2.8 0.0062 15.3 2.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.1 EPR78274.1 - 0.0071 15.9 7.6 0.43 10.1 5.2 2.7 1 1 0 1 1 1 1 AAA domain SNase PF00565.12 EPR78275.1 - 8.4e-20 71.0 0.2 1.2e-19 70.5 0.2 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SKG6 PF08693.5 EPR78275.1 - 0.03 13.6 0.6 0.078 12.3 0.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amidase_6 PF12671.2 EPR78275.1 - 0.06 13.3 0.5 0.096 12.7 0.3 1.3 1 0 0 1 1 1 0 Putative amidase domain eIF-5_eIF-2B PF01873.12 EPR78276.1 - 6.4e-30 103.3 0.7 9.2e-30 102.8 0.5 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 tRNA-synt_1f PF01921.13 EPR78276.1 - 0.048 12.3 1.0 0.94 8.0 0.2 2.2 1 1 1 2 2 2 0 tRNA synthetases class I (K) IF2_N PF04760.10 EPR78276.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF1451 PF07295.6 EPR78276.1 - 0.18 11.5 1.5 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) TF_Zn_Ribbon PF08271.7 EPR78276.1 - 0.21 10.9 1.9 5.2 6.4 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.1 EPR78276.1 - 0.23 11.8 0.8 1.8 8.9 0.7 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar E1-E2_ATPase PF00122.15 EPR78277.1 - 5.7e-50 169.5 0.2 2.7e-49 167.2 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPR78277.1 - 1.3e-15 57.1 0.2 2.4e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EPR78277.1 - 5.2e-08 33.5 0.0 1.3e-07 32.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPR78277.1 - 1.6e-06 28.4 0.0 7.1e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EPR78278.1 - 6.8e-30 103.9 19.0 1.2e-29 103.0 13.2 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Ocular_alb PF02101.10 EPR78278.1 - 0.04 12.5 0.2 0.04 12.5 0.1 2.0 1 1 1 2 2 2 0 Ocular albinism type 1 protein DUF3980 PF13140.1 EPR78278.1 - 0.044 14.0 0.4 0.044 14.0 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3980) Abhydrolase_5 PF12695.2 EPR78279.1 - 2.7e-08 33.6 0.0 4.5e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPR78279.1 - 4.5e-08 33.2 0.0 7.8e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPR78279.1 - 1.4e-06 28.0 0.0 1.9e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EPR78279.1 - 0.00011 21.4 0.2 0.00036 19.6 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 EPR78279.1 - 0.00015 21.1 0.1 0.00025 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 EPR78279.1 - 0.002 17.9 0.2 0.024 14.3 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) LCAT PF02450.10 EPR78279.1 - 0.0045 16.0 0.6 0.01 14.8 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.3 EPR78279.1 - 0.0061 16.3 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase MAGE PF01454.14 EPR78280.1 - 6.5e-06 25.6 1.3 8.8e-06 25.1 0.9 1.2 1 0 0 1 1 1 1 MAGE family RRF PF01765.14 EPR78280.1 - 0.11 11.9 1.0 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 Ribosome recycling factor E1-E2_ATPase PF00122.15 EPR78281.1 - 1.8e-47 161.3 3.5 1.8e-47 161.3 2.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EPR78281.1 - 2.5e-05 23.6 0.1 0.00011 21.5 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus MgtE PF01769.11 EPR78281.1 - 1.2 9.4 10.2 1.1 9.5 2.2 2.7 2 1 1 3 3 3 0 Divalent cation transporter SHMT PF00464.14 EPR78282.1 - 1.4e-80 270.6 0.0 2.3e-80 269.9 0.0 1.3 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EPR78282.1 - 2.3e-06 26.8 0.1 6.8e-06 25.2 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPR78282.1 - 8.6e-05 21.8 0.0 0.00067 18.8 0.0 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase Tombus_P19 PF03220.8 EPR78283.1 - 0.044 13.1 0.0 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Tombusvirus P19 core protein Ribosomal_L35Ae PF01247.13 EPR78285.1 - 7.3e-19 67.3 0.8 9.2e-19 67.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae DUF663 PF04950.7 EPR78285.1 - 0.0019 17.1 1.1 0.0025 16.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF663) RimM PF01782.13 EPR78285.1 - 0.022 14.6 0.1 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain LRR_8 PF13855.1 EPR78286.1 - 2.4e-28 97.6 51.3 1.3e-09 37.6 4.0 7.5 5 1 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EPR78286.1 - 9.5e-26 88.9 68.9 2.1e-05 24.0 0.5 9.5 7 2 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78286.1 - 1.2e-10 39.8 49.7 0.18 11.9 0.9 12.8 12 2 0 12 12 12 6 Leucine Rich Repeat LRR_7 PF13504.1 EPR78286.1 - 6.8e-07 28.4 32.6 1.5 9.3 0.0 11.5 13 0 0 13 13 13 4 Leucine rich repeat LRR_6 PF13516.1 EPR78286.1 - 0.17 12.0 38.3 5.7 7.3 0.0 9.1 10 0 0 10 10 10 0 Leucine Rich repeat UCH PF00443.24 EPR78287.1 - 0.00053 19.1 0.2 0.00053 19.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78287.1 - 0.0012 18.3 0.1 0.0013 18.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1647 PF07801.6 EPR78288.1 - 0.093 12.2 5.6 0.02 14.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1647) Ribosomal_S8e PF01201.17 EPR78289.1 - 2e-43 147.7 1.7 2.4e-43 147.4 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e GDI PF00996.13 EPR78290.1 - 2.5e-06 26.0 1.1 2.8e-05 22.6 0.1 2.4 1 1 1 2 2 2 2 GDP dissociation inhibitor Glycos_transf_2 PF00535.21 EPR78290.1 - 0.078 12.6 1.8 0.24 11.0 0.0 2.5 2 1 1 3 3 3 0 Glycosyl transferase family 2 rve PF00665.21 EPR78291.1 - 0.026 14.6 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain DUF581 PF04570.9 EPR78291.1 - 0.097 11.9 0.1 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF581) Rpr2 PF04032.11 EPR78292.1 - 2.7 7.9 6.8 0.91 9.4 2.4 1.9 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DDE_Tnp_IS1595 PF12762.2 EPR78293.1 - 2.9e-14 53.1 0.6 3.3e-14 52.9 0.4 1.2 1 0 0 1 1 1 1 ISXO2-like transposase domain Ribonuc_red_sm PF00268.16 EPR78293.1 - 0.0051 15.8 0.2 0.0054 15.7 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1128 PF06569.6 EPR78293.1 - 0.27 10.9 2.1 0.4 10.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) RicinB_lectin_2 PF14200.1 EPR78295.1 - 0.0027 18.0 0.1 0.19 12.0 0.1 2.4 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EPR78295.1 - 0.0046 16.9 0.0 0.012 15.6 0.1 1.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain DUF3614 PF12267.3 EPR78295.1 - 0.042 14.1 0.2 0.09 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Cornifin PF02389.10 EPR78295.1 - 0.046 13.5 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Cornifin (SPRR) family TryThrA_C PF12319.3 EPR78295.1 - 6.3 5.9 12.9 0.49 9.5 4.2 2.2 1 1 1 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal C1q PF00386.16 EPR78297.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 C1q domain PUA PF01472.15 EPR78299.1 - 3.1e-08 33.2 0.0 4.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 PUA domain zf-C2H2 PF00096.21 EPR78301.1 - 4.2e-11 42.5 40.8 0.0015 18.7 4.1 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPR78301.1 - 2.8e-07 30.4 35.4 0.0066 16.7 3.1 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPR78301.1 - 0.0074 16.1 2.6 0.0074 16.1 1.8 4.0 3 1 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPR78301.1 - 4 7.9 39.0 0.44 10.9 4.0 5.6 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPR78301.1 - 4.5 7.5 31.8 0.63 10.2 0.3 4.6 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF1392 PF07154.6 EPR78302.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1392) H-kinase_dim PF02895.9 EPR78303.1 - 0.025 14.9 0.1 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain YhdB PF14148.1 EPR78303.1 - 0.12 12.1 2.5 0.13 12.0 0.3 1.9 1 1 1 2 2 2 0 YhdB-like protein DUF1474 PF07342.6 EPR78303.1 - 0.35 11.1 3.6 0.64 10.2 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Baculo_11_kDa PF06143.6 EPR78305.1 - 4.6 6.6 10.1 31 3.9 0.4 3.3 3 0 0 3 3 3 0 Baculovirus 11 kDa family UQ_con PF00179.21 EPR78306.1 - 5.5e-23 80.9 2.6 9.2e-23 80.2 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPR78306.1 - 1.7e-06 27.8 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EPR78306.1 - 0.002 17.7 0.3 0.0033 17.0 0.1 1.4 1 1 0 1 1 1 1 UEV domain KbaA PF14089.1 EPR78307.1 - 0.07 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation DUF3633 PF12315.3 EPR78308.1 - 0.18 11.1 1.1 0.27 10.5 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3633) Zip PF02535.17 EPR78308.1 - 0.86 8.5 4.9 1.3 7.9 3.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BSMAP PF12280.3 EPR78308.1 - 3.4 7.4 11.1 9.9 5.9 0.3 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein Pox_Ag35 PF03286.9 EPR78308.1 - 4.7 6.6 25.9 0.072 12.6 10.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PFU PF09070.6 EPR78309.1 - 5.6e-10 39.2 6.4 5.6e-10 39.2 4.4 1.8 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) RRS1 PF04939.7 EPR78312.1 - 1.4e-12 47.3 3.0 2e-12 46.9 2.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DUF2708 PF10917.3 EPR78312.1 - 1.3 8.8 3.5 20 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2708) TFIIS_M PF07500.9 EPR78312.1 - 2.7 8.1 8.3 0.39 10.8 3.1 1.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain zf-DHHC PF01529.15 EPR78313.1 - 1.4e-15 57.1 26.1 1.2e-14 54.1 18.1 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase Acyl_transf_3 PF01757.17 EPR78313.1 - 0.028 13.2 0.2 0.039 12.7 0.1 1.1 1 0 0 1 1 1 0 Acyltransferase family ER_lumen_recept PF00810.13 EPR78313.1 - 0.16 12.4 4.8 15 6.0 3.1 2.4 2 1 0 2 2 2 0 ER lumen protein retaining receptor Sar8_2 PF03058.9 EPR78313.1 - 4 7.8 10.4 13 6.1 4.8 2.4 2 0 0 2 2 2 0 Sar8.2 family VirB3 PF05101.8 EPR78314.1 - 2 8.4 9.0 0.98 9.4 3.6 2.1 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein DRMBL PF07522.9 EPR78315.1 - 5.3e-17 61.8 0.1 1.2e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPR78315.1 - 2.7e-08 33.5 3.5 1.9e-07 30.7 1.7 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPR78315.1 - 0.0051 16.4 0.3 0.014 15.0 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EPR78315.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase CoaE PF01121.15 EPR78316.1 - 1.3e-12 47.5 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EPR78316.1 - 1.4e-09 38.3 2.3 2.6e-09 37.4 1.5 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR78316.1 - 4.7e-07 30.6 0.4 9.9e-07 29.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPR78316.1 - 0.00074 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EPR78316.1 - 0.00075 19.4 0.4 0.001 19.0 0.3 1.1 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.1 EPR78316.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPR78316.1 - 0.016 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPR78316.1 - 0.05 12.4 0.3 0.068 12.0 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EPR78316.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 EPR78316.1 - 0.087 12.6 0.7 0.37 10.6 0.5 2.1 1 1 0 1 1 1 0 Shikimate kinase ABC_tran PF00005.22 EPR78316.1 - 0.089 13.0 0.6 0.24 11.7 0.6 1.5 1 1 0 1 1 1 0 ABC transporter Clp1 PF06807.9 EPR78317.1 - 2.8e-08 33.7 0.0 4.3e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DDE_Tnp_IS1595 PF12762.2 EPR78318.1 - 3.6e-18 65.8 0.2 6.6e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS1595 PF12762.2 EPR78319.1 - 5.7e-17 61.9 0.0 6.6e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.1 EPR78319.1 - 0.0061 16.5 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 DDE domain DDE_3 PF13358.1 EPR78319.1 - 0.1 12.3 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease DASH_Dad4 PF08650.5 EPR78319.1 - 0.18 11.7 2.5 11 6.0 0.1 2.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 zf-H2C2 PF09337.5 EPR78320.1 - 0.36 10.2 7.4 0.11 11.8 2.6 1.9 1 1 1 2 2 2 0 His(2)-Cys(2) zinc finger DUF3671 PF12420.3 EPR78320.1 - 1.3 9.0 9.4 1.7 8.6 6.5 1.3 1 1 0 1 1 1 0 Protein of unknown function Phage_int_SAM_3 PF14659.1 EPR78320.1 - 3 8.1 6.8 0.31 11.3 1.5 1.8 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain SAP PF02037.22 EPR78321.1 - 1.4e-07 30.8 0.1 2.1e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 SAP domain Ufd2P_core PF10408.4 EPR78323.1 - 0.0095 14.2 2.0 0.011 13.9 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core DUF1978 PF09321.5 EPR78324.1 - 0.035 13.5 1.1 0.053 12.9 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) CH PF00307.26 EPR78325.1 - 2e-15 56.7 0.0 2.7e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF2061 PF09834.4 EPR78326.1 - 0.087 13.0 1.6 0.14 12.3 0.3 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2061) Syja_N PF02383.13 EPR78327.1 - 5e-48 163.5 8.9 5e-48 163.5 6.2 2.2 2 1 0 2 2 2 1 SacI homology domain Tubulin PF00091.20 EPR78328.1 - 5.4e-71 238.8 0.0 8.2e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPR78328.1 - 8.5e-48 161.5 0.0 1.3e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPR78328.1 - 1.2e-07 31.7 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF2206 PF09971.4 EPR78329.1 - 0.0052 15.6 0.1 0.0073 15.1 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) ETRAMP PF09716.5 EPR78329.1 - 0.083 12.8 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ExbD PF02472.11 EPR78329.1 - 0.12 12.3 0.5 0.12 12.3 0.3 1.3 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR OppC_N PF12911.2 EPR78331.1 - 0.015 14.6 1.4 0.03 13.6 1.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4091 PF13320.1 EPR78331.1 - 0.015 15.1 1.1 6.5 6.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) RRM_5 PF13893.1 EPR78332.1 - 0.00038 20.2 0.0 0.00097 18.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR78332.1 - 0.0029 17.5 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RasGEF_N PF00618.15 EPR78332.1 - 9.4 6.4 7.5 3.5 7.7 0.1 3.1 2 1 1 3 3 3 0 RasGEF N-terminal motif PRO8NT PF08082.6 EPR78333.1 - 3.2e-20 72.3 6.4 4.2e-20 71.9 0.3 2.5 1 1 1 3 3 3 2 PRO8NT (NUC069), PrP8 N-terminal domain Spore_III_AF PF09581.5 EPR78335.1 - 0.017 14.9 8.9 0.054 13.3 4.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) MutS_IV PF05190.13 EPR78336.1 - 0.19 11.8 6.8 0.34 11.1 4.7 1.5 1 0 0 1 1 1 0 MutS family domain IV Lipocalin_4 PF13648.1 EPR78336.1 - 5.1 7.7 6.9 19 5.9 4.8 2.0 1 1 0 1 1 1 0 Lipocalin-like domain DUF2870 PF11069.3 EPR78336.1 - 8.4 6.5 8.3 1.6 8.8 2.6 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2870) Cnd2 PF05786.9 EPR78337.1 - 6.6e-23 81.1 34.4 2e-19 69.6 2.1 4.1 2 1 2 4 4 4 2 Condensin complex subunit 2 Rad21_Rec8_N PF04825.8 EPR78337.1 - 0.026 14.4 1.2 0.043 13.7 0.1 2.0 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein bZIP_1 PF00170.16 EPR78338.1 - 0.0054 16.6 8.1 0.55 10.2 0.2 3.0 1 1 1 2 2 2 2 bZIP transcription factor IncA PF04156.9 EPR78338.1 - 0.036 13.6 3.8 0.068 12.7 2.6 1.5 1 0 0 1 1 1 0 IncA protein CPSase_sm_chain PF00988.17 EPR78338.1 - 0.079 12.4 0.5 0.19 11.2 0.3 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain DivIC PF04977.10 EPR78338.1 - 0.28 10.7 8.5 3.7 7.0 2.4 2.7 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.7 EPR78338.1 - 1.4 9.3 4.4 4.4 7.7 0.6 2.8 2 1 1 3 3 3 0 SlyX Peptidase_M1 PF01433.15 EPR78339.1 - 8e-117 390.6 7.1 1.3e-116 389.9 4.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EPR78339.1 - 2.8e-16 59.7 0.0 4.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Aa_trans PF01490.13 EPR78340.1 - 8.9e-35 119.9 51.1 4.7e-34 117.5 35.4 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPR78340.1 - 2.2e-05 23.4 22.7 2.2e-05 23.4 15.7 2.9 1 1 1 3 3 3 3 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 EPR78340.1 - 0.057 11.9 55.7 0.11 11.0 38.6 1.4 1 1 0 1 1 1 0 Amino acid permease HUN PF08729.5 EPR78341.1 - 2.4e-10 40.1 0.8 2.4e-10 40.1 0.6 2.4 2 1 0 2 2 2 1 HPC2 and ubinuclein domain DUF1168 PF06658.7 EPR78341.1 - 4.6 6.7 16.3 4 6.9 10.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) TPT PF03151.11 EPR78342.1 - 5.1e-19 68.4 16.6 5.1e-19 68.4 11.5 2.5 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EPR78342.1 - 0.00022 21.2 42.6 0.00071 19.6 10.3 3.4 2 2 1 3 3 3 2 EamA-like transporter family DUF1510 PF07423.6 EPR78343.1 - 0.0029 16.9 11.7 0.0029 16.9 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ETRAMP PF09716.5 EPR78343.1 - 0.056 13.4 0.6 0.21 11.5 0.5 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ycf1 PF05758.7 EPR78343.1 - 0.19 9.3 7.0 0.19 9.3 4.9 1.0 1 0 0 1 1 1 0 Ycf1 Mem_trans PF03547.13 EPR78343.1 - 0.42 8.8 4.0 0.46 8.7 2.8 1.1 1 0 0 1 1 1 0 Membrane transport protein SID-1_RNA_chan PF13965.1 EPR78343.1 - 1.6 6.8 3.6 1.5 6.8 2.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Polyoma_lg_T_C PF06431.6 EPR78343.1 - 2.3 6.7 7.4 2.4 6.7 5.1 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DUF775 PF05603.7 EPR78343.1 - 2.4 7.6 11.6 3.4 7.1 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4629 PF15442.1 EPR78343.1 - 3.3 7.8 15.1 3.8 7.6 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DDHD PF02862.12 EPR78343.1 - 3.7 7.2 11.1 4 7.1 7.7 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EPR78343.1 - 8.4 4.2 14.9 8.5 4.2 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein ERAP1_C PF11838.3 EPR78345.1 - 7.3e-09 35.3 0.0 9e-09 35.0 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain RNR_N PF08343.5 EPR78345.1 - 0.072 12.9 4.6 0.2 11.4 1.5 2.5 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal Chs3p PF12271.3 EPR78347.1 - 7.2e-28 97.3 29.5 9.2e-28 97.0 20.4 1.1 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Maf1 PF09174.5 EPR78349.1 - 0.092 12.5 7.9 0.21 11.4 5.5 1.8 1 1 0 1 1 1 0 Maf1 regulator MMR_HSR1 PF01926.18 EPR78350.1 - 1.7e-18 66.6 0.5 3.7e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 EPR78350.1 - 3.7e-17 61.9 0.1 6.4e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EPR78350.1 - 1e-10 41.1 0.0 2.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EPR78350.1 - 0.0036 16.5 0.6 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EPR78350.1 - 0.0065 16.9 0.1 0.024 15.1 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EPR78350.1 - 0.01 15.7 0.8 3.2 7.5 0.0 2.7 1 1 1 2 2 2 2 Dynamin family AAA_28 PF13521.1 EPR78350.1 - 0.055 13.4 0.1 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EPR78350.1 - 0.07 11.8 0.3 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AAA_22 PF13401.1 EPR78350.1 - 0.073 13.2 0.3 0.32 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPR78350.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain zf-RING_6 PF14835.1 EPR78351.1 - 1.1e-05 25.0 2.3 2.3e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EPR78351.1 - 0.00043 19.9 13.2 0.0013 18.4 9.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EPR78351.1 - 0.037 13.5 4.7 0.091 12.3 3.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 EPR78351.1 - 0.41 10.7 12.9 2 8.5 8.9 2.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E_raikovi_mat PF06360.6 EPR78351.1 - 2.2 8.5 8.3 1.6 9.0 4.0 2.1 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone zf-RING_2 PF13639.1 EPR78351.1 - 2.8 7.8 12.8 13 5.7 9.0 2.1 1 1 1 2 2 2 0 Ring finger domain Ham1p_like PF01725.11 EPR78352.1 - 1.5e-25 89.6 0.0 1.8e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family TB2_DP1_HVA22 PF03134.14 EPR78353.1 - 4.7e-13 48.6 7.7 4.7e-13 48.6 5.3 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family RIO1 PF01163.17 EPR78354.1 - 1.6e-56 190.7 0.9 1.6e-56 190.7 0.6 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EPR78354.1 - 0.03 14.0 0.0 0.29 10.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rootletin PF15035.1 EPR78354.1 - 0.26 11.2 11.4 0.4 10.6 0.3 3.0 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion PK PF00224.16 EPR78355.1 - 4.6e-97 324.7 5.5 6.1e-97 324.3 3.8 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 EPR78355.1 - 6.4e-06 25.2 0.7 1.9e-05 23.6 0.1 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family WD40 PF00400.27 EPR78357.1 - 0.0046 16.7 0.0 0.93 9.4 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPR78357.1 - 0.0075 15.1 1.9 0.0093 14.7 1.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Bap31 PF05529.7 EPR78359.1 - 2.3e-18 66.3 21.4 8.3e-13 48.2 4.8 2.1 1 1 1 2 2 2 2 B-cell receptor-associated protein 31-like Swi5 PF07061.6 EPR78359.1 - 0.066 13.0 6.4 0.13 12.0 4.4 1.6 1 1 0 1 1 1 0 Swi5 DUF3788 PF12663.2 EPR78359.1 - 0.13 11.9 2.7 3.9 7.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) TT_ORF1 PF02956.9 EPR78359.1 - 0.24 9.8 3.3 0.3 9.4 2.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 Beta-Casp PF10996.3 EPR78362.1 - 0.0075 16.2 0.4 0.0075 16.2 0.3 2.7 2 0 0 2 2 2 1 Beta-Casp domain DUF226 PF02890.9 EPR78363.1 - 0.00014 21.6 2.9 0.00014 21.6 2.0 3.4 3 1 0 3 3 3 1 Borrelia family of unknown function DUF226 Mucin PF01456.12 EPR78363.1 - 0.0024 17.6 1.7 0.0024 17.6 1.2 3.1 3 0 0 3 3 3 2 Mucin-like glycoprotein DUF702 PF05142.7 EPR78363.1 - 0.82 9.8 18.1 1.7 8.7 1.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Vfa1 PF08432.5 EPR78363.1 - 4.3 7.3 33.0 2.2 8.2 4.7 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpb8 PF03870.10 EPR78364.1 - 2.3e-11 44.0 1.6 7.9e-08 32.5 0.2 2.0 1 1 1 2 2 2 2 RNA polymerase Rpb8 DUF1934 PF09148.5 EPR78364.1 - 0.012 15.2 0.9 0.021 14.5 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1934) LMBR1 PF04791.11 EPR78365.1 - 0.00034 19.3 1.5 0.00042 19.0 1.0 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Otopetrin PF03189.8 EPR78365.1 - 0.0071 15.4 6.5 0.0084 15.1 4.5 1.1 1 0 0 1 1 1 1 Otopetrin DUF2975 PF11188.3 EPR78365.1 - 0.035 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Glyco_transf_7C PF02709.9 EPR78365.1 - 0.062 12.7 0.4 0.16 11.4 0.3 1.7 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Rota_VP2 PF05087.7 EPR78365.1 - 1.5 6.6 24.1 1.8 6.4 16.7 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF1510 PF07423.6 EPR78365.1 - 1.6 8.0 28.3 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SH PF01445.12 EPR78365.1 - 2.1 8.0 5.0 4.3 7.0 3.5 1.6 1 1 0 1 1 1 0 Viral small hydrophobic protein Baculo_11_kDa PF06143.6 EPR78365.1 - 4.2 6.7 9.5 0.086 12.2 1.2 2.2 2 1 0 2 2 2 0 Baculovirus 11 kDa family zf-RING_2 PF13639.1 EPR78366.1 - 2.1e-05 24.2 9.5 2.7e-05 23.9 6.0 1.7 2 0 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EPR78366.1 - 0.001 18.8 1.7 0.0024 17.6 1.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPR78366.1 - 0.0017 18.3 13.6 0.0033 17.4 9.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 EPR78366.1 - 0.0053 16.8 7.6 0.014 15.4 4.6 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger C1_1 PF00130.17 EPR78366.1 - 0.025 14.3 13.0 0.029 14.1 5.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.3 EPR78366.1 - 0.072 13.0 13.7 0.052 13.5 7.4 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.24 EPR78366.1 - 0.095 12.4 11.0 0.29 10.8 7.6 1.9 1 1 0 1 1 1 0 PHD-finger Bromodomain PF00439.20 EPR78367.1 - 0.0045 16.8 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Bromodomain Ras PF00071.17 EPR78369.1 - 8.7e-49 165.0 0.2 1e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR78369.1 - 9.6e-20 71.2 0.0 1.5e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPR78369.1 - 3.2e-17 62.3 0.1 3.8e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPR78369.1 - 8.3e-08 31.6 0.2 1.2e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPR78369.1 - 1e-07 31.8 0.1 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPR78369.1 - 1e-06 28.3 0.0 1.9e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPR78369.1 - 3.1e-06 26.5 0.0 4.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EPR78369.1 - 0.00011 21.6 0.1 0.0023 17.4 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EPR78369.1 - 0.00024 19.9 4.5 0.069 11.8 0.1 3.1 1 1 1 2 2 2 2 G-protein alpha subunit YTH PF04146.10 EPR78369.1 - 0.0024 17.4 0.1 0.0039 16.7 0.1 1.4 1 1 0 1 1 1 1 YT521-B-like domain FeoB_N PF02421.13 EPR78369.1 - 0.0029 16.8 0.2 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EPR78369.1 - 0.013 15.2 0.3 0.017 14.7 0.0 1.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EPR78369.1 - 0.044 14.0 0.2 0.072 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPR78369.1 - 0.063 13.1 1.2 0.39 10.6 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EPR78369.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rtt106 PF08512.7 EPR78369.1 - 0.13 12.2 0.4 0.42 10.6 0.1 2.2 2 1 0 2 2 2 0 Histone chaperone Rttp106-like LRR_8 PF13855.1 EPR78372.1 - 2.9e-19 68.5 59.3 4.1e-05 23.2 4.5 8.1 5 3 3 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 EPR78372.1 - 9.7e-16 57.0 72.7 2.8e-07 30.0 4.5 9.8 6 4 5 11 11 11 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78372.1 - 0.083 12.9 55.6 0.27 11.3 0.1 12.1 13 0 0 13 13 13 0 Leucine Rich Repeat LRR_5 PF13306.1 EPR78372.1 - 3.2 7.4 45.2 0.019 14.6 3.6 6.0 2 2 4 6 6 6 0 Leucine rich repeats (6 copies) zf-CCCH PF00642.19 EPR78373.1 - 5.7e-08 32.2 8.5 0.0012 18.4 0.5 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EPR78373.1 - 4.4e-05 23.0 0.1 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR78373.1 - 0.0015 18.3 0.1 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR78373.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LSM14 PF12701.2 EPR78374.1 - 6.4e-13 48.3 0.2 1.4e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain DAO PF01266.19 EPR78375.1 - 1.1e-40 139.7 0.0 1.5e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPR78375.1 - 6.4e-09 35.1 1.0 0.00019 20.3 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EPR78375.1 - 7e-06 25.3 0.3 1.1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPR78375.1 - 1.2e-05 25.3 0.4 5.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPR78375.1 - 0.0005 19.0 1.4 0.011 14.6 0.3 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EPR78375.1 - 0.0081 14.6 0.6 0.0081 14.6 0.4 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPR78375.1 - 0.0094 15.9 0.9 0.024 14.6 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPR78375.1 - 0.029 13.4 0.1 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EPR78375.1 - 0.15 10.9 0.6 0.24 10.3 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPR78375.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Kinesin PF00225.18 EPR78376.1 - 1.4e-82 277.1 10.5 1.4e-82 277.1 7.3 2.0 2 0 0 2 2 2 1 Kinesin motor domain UvsW PF11637.3 EPR78376.1 - 0.74 9.5 8.8 0.35 10.5 1.3 3.1 3 0 0 3 3 3 0 ATP-dependant DNA helicase UvsW HhH-GPD PF00730.20 EPR78377.1 - 3.8e-17 62.5 0.1 5.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPR78377.1 - 0.0025 17.4 0.3 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2400 PF09674.5 EPR78377.1 - 0.026 14.2 0.7 0.12 12.0 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) HHH_8 PF14716.1 EPR78377.1 - 0.068 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain EFG_C PF00679.19 EPR78378.1 - 0.053 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus RNA_pol_Rpb1_5 PF04998.12 EPR78379.1 - 2.1 7.5 17.6 3.1 6.9 12.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 NMD3 PF04981.8 EPR78380.1 - 4.8e-30 104.4 6.6 5.4e-30 104.2 4.6 1.0 1 0 0 1 1 1 1 NMD3 family ThylakoidFormat PF11264.3 EPR78381.1 - 0.015 14.9 1.9 0.018 14.6 1.3 1.1 1 0 0 1 1 1 0 Thylakoid formation protein GGDN PF05165.7 EPR78381.1 - 0.093 11.7 0.0 0.093 11.7 0.0 1.5 2 0 0 2 2 2 0 GGDN family Tyrosinase PF00264.15 EPR78383.1 - 1.3e-13 51.6 1.3 1.6e-13 51.3 0.9 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HemN_C PF06969.11 EPR78383.1 - 0.052 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 HemN C-terminal domain DUF2624 PF11116.3 EPR78384.1 - 0.0072 16.8 1.7 16 6.0 0.0 4.0 2 1 2 4 4 4 1 Protein of unknown function (DUF2624) CLAMP PF14769.1 EPR78384.1 - 0.085 13.0 0.3 0.085 13.0 0.2 2.3 2 2 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 BRCT_assoc PF12820.2 EPR78385.1 - 0.0008 19.2 0.3 0.0008 19.2 0.2 1.6 2 0 0 2 2 2 1 Serine-rich domain associated with BRCT Cyt-b5 PF00173.23 EPR78386.1 - 0.00016 21.4 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4064 PF13273.1 EPR78386.1 - 0.019 15.0 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF912 PF06024.7 EPR78386.1 - 9.1 6.4 6.7 18 5.4 4.6 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 EPR78388.1 - 8.8e-43 146.3 0.1 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78388.1 - 4.2e-27 94.8 0.0 6.3e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Filo_glycop PF01611.11 EPR78388.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein Kinase-like PF14531.1 EPR78388.1 - 0.012 14.5 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EPR78388.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TIP41 PF04176.8 EPR78388.1 - 0.079 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 TIP41-like family Telomerase_RBD PF12009.3 EPR78389.1 - 2.4e-09 37.2 7.3 2.4e-09 37.2 5.1 1.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain Pkinase PF00069.20 EPR78390.1 - 2.6e-37 128.3 0.6 3.6e-37 127.9 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78390.1 - 1.6e-18 66.6 0.6 4.7e-18 65.2 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EPR78390.1 - 0.0051 15.9 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cortex-I_coil PF09304.5 EPR78390.1 - 0.031 14.3 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Ribosomal_S11 PF00411.14 EPR78391.1 - 2e-30 105.1 1.2 2.4e-30 104.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Spore_III_AF PF09581.5 EPR78391.1 - 0.06 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) LRR_4 PF12799.2 EPR78393.1 - 0.014 14.9 2.6 0.014 14.9 1.8 1.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPR78393.1 - 3 8.4 5.3 12 6.5 0.1 3.4 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 EPR78393.1 - 3.7 7.9 9.4 4 7.8 0.2 3.4 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 EPR78394.1 - 1e-19 70.0 62.4 5e-07 29.3 2.1 7.5 4 2 4 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 EPR78394.1 - 1.5e-19 69.2 73.3 9.1e-07 28.3 0.7 10.0 7 3 2 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78394.1 - 1.5e-08 33.4 68.3 0.022 14.7 0.1 14.3 13 3 2 15 15 15 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR78394.1 - 4.2e-08 32.0 34.7 0.56 10.6 0.0 12.9 14 1 0 14 14 14 4 Leucine rich repeat LRR_6 PF13516.1 EPR78394.1 - 7.8 6.9 60.1 1.4 9.2 0.4 12.9 15 0 0 15 15 15 0 Leucine Rich repeat FliP PF00813.15 EPR78395.1 - 2.1 8.0 3.6 1.6 8.3 0.1 2.3 2 1 0 2 2 2 0 FliP family SpoU_sub_bind PF08032.7 EPR78395.1 - 8.5 6.6 12.2 8.1 6.6 0.3 3.8 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding RNA_pol_Rbc25 PF08292.7 EPR78396.1 - 8.7e-15 55.0 7.2 4.7e-12 46.1 1.3 2.8 2 1 1 3 3 3 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EPR78396.1 - 6e-05 23.0 0.1 8.7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Beta-Casp PF10996.3 EPR78398.1 - 8.9e-21 74.1 0.0 4.2e-20 71.9 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EPR78398.1 - 2.4e-16 59.9 0.2 3.9e-16 59.2 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPR78398.1 - 3.6e-14 52.7 0.1 8.1e-13 48.3 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EPR78398.1 - 2e-11 43.4 0.0 4.7e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EPR78398.1 - 2.5e-07 30.5 0.0 5.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SNF2_N PF00176.18 EPR78399.1 - 2.3e-71 240.0 2.8 2.3e-71 240.0 2.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPR78399.1 - 1.8e-16 59.7 0.0 5.9e-16 58.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLIDE PF09111.5 EPR78399.1 - 1.1e-13 50.9 7.7 1.1e-13 50.9 5.3 2.6 2 0 0 2 2 2 1 SLIDE ResIII PF04851.10 EPR78399.1 - 1.8e-10 40.9 0.1 1.8e-10 40.9 0.0 3.8 3 2 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPR78399.1 - 1.8e-07 30.8 0.2 5.4e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HAND PF09110.6 EPR78399.1 - 0.00032 21.0 5.4 0.0014 19.0 0.9 3.3 1 1 1 2 2 2 1 HAND AAA_10 PF12846.2 EPR78399.1 - 0.02 14.3 3.7 4.5 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain YlaH PF14036.1 EPR78400.1 - 0.019 15.0 7.7 0.019 15.0 5.3 2.0 2 0 0 2 2 2 0 YlaH-like protein RELT PF12606.3 EPR78400.1 - 2.1 7.5 4.7 4.2 6.5 3.2 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 YwiC PF14256.1 EPR78401.1 - 0.57 10.2 12.8 1 9.4 5.5 2.7 2 1 0 2 2 2 0 YwiC-like protein Sybindin PF04099.7 EPR78402.1 - 1.6e-07 31.0 4.0 2.4e-07 30.5 2.7 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EPR78402.1 - 0.13 12.0 3.4 0.18 11.6 2.3 1.4 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region RhoGEF PF00621.15 EPR78403.1 - 2.4e-15 56.8 4.7 2.4e-15 56.8 3.2 2.7 2 1 0 2 2 2 1 RhoGEF domain NOC3p PF07540.6 EPR78404.1 - 2.1e-09 37.5 4.0 2.1e-09 37.5 2.8 3.7 4 1 0 4 4 4 1 Nucleolar complex-associated protein Serglycin PF04360.7 EPR78405.1 - 0.021 14.5 0.4 0.021 14.5 0.3 2.0 2 1 0 2 2 2 0 Serglycin DUF1168 PF06658.7 EPR78405.1 - 0.28 10.7 13.3 0.51 9.8 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) LRR_4 PF12799.2 EPR78406.1 - 2.7e-22 77.9 76.3 1.7e-06 27.4 2.2 9.0 7 2 1 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78406.1 - 9.3e-20 70.1 61.8 7.8e-07 28.7 2.5 7.6 3 3 4 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EPR78406.1 - 5.8e-09 34.7 66.5 0.084 12.9 0.2 13.6 12 1 1 13 13 13 6 Leucine Rich Repeat LRR_7 PF13504.1 EPR78406.1 - 5.6e-07 28.7 37.7 4.8 7.8 0.0 12.5 11 2 2 13 13 13 4 Leucine rich repeat MS_channel PF00924.13 EPR78407.1 - 9.6e-14 51.1 0.1 9.6e-14 51.1 0.1 2.1 3 0 0 3 3 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPR78407.1 - 2.7e-05 23.1 1.7 3.6e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EPR78407.1 - 0.00088 18.8 0.1 0.0025 17.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPR78407.1 - 0.0009 18.9 0.1 0.0047 16.7 0.0 2.3 2 0 0 2 2 1 1 EF-hand domain EF-hand_7 PF13499.1 EPR78407.1 - 0.019 15.1 0.0 0.066 13.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair DUF912 PF06024.7 EPR78407.1 - 0.027 14.5 1.1 0.027 14.5 0.8 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EF-hand_5 PF13202.1 EPR78407.1 - 0.041 13.2 0.1 0.096 12.0 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF2214 PF09980.4 EPR78407.1 - 0.096 12.4 4.9 0.21 11.3 3.0 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2214) DUF2681 PF10883.3 EPR78407.1 - 0.12 12.6 1.2 10 6.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3753 PF12575.3 EPR78407.1 - 2 8.2 24.0 0.29 10.9 0.1 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3753) DUF4131 PF13567.1 EPR78407.1 - 3 7.1 5.1 1.7 7.9 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) CAP_GLY PF01302.20 EPR78408.1 - 7e-18 64.0 0.5 1.2e-17 63.2 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain Phage_lambd_GpG PF06894.6 EPR78408.1 - 0.12 12.0 1.4 0.38 10.3 0.2 2.2 2 1 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) JAB PF01398.16 EPR78411.1 - 1.2e-19 70.1 0.0 3.1e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPR78411.1 - 0.00055 20.0 4.9 0.0012 18.9 3.4 1.5 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF4334 PF14232.1 EPR78411.1 - 0.0074 15.9 0.1 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) DUF4175 PF13779.1 EPR78411.1 - 0.32 8.6 1.5 0.42 8.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mitovir_RNA_pol PF05919.6 EPR78412.1 - 0.45 9.3 6.5 0.93 8.3 0.0 2.0 1 1 1 2 2 2 0 Mitovirus RNA-dependent RNA polymerase Fcf1 PF04900.7 EPR78413.1 - 4.8e-09 36.2 5.1 5.9e-08 32.7 0.8 2.4 2 0 0 2 2 2 2 Fcf1 RNA_pol_3_Rpc31 PF11705.3 EPR78413.1 - 0.051 13.5 13.2 0.072 13.0 9.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 V_ATPase_I PF01496.14 EPR78413.1 - 0.25 9.1 9.5 0.3 8.8 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1510 PF07423.6 EPR78413.1 - 1.5 8.1 18.8 2.4 7.4 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spc24 PF08286.6 EPR78413.1 - 10 5.8 22.9 19 4.9 15.2 1.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Aldo_ket_red PF00248.16 EPR78414.1 - 1.4e-47 161.9 0.8 1.9e-47 161.4 0.6 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Med27 PF11571.3 EPR78415.1 - 2 8.5 6.2 3 8.0 0.0 3.6 2 2 2 4 4 4 0 Mediator complex subunit 27 WD40 PF00400.27 EPR78417.1 - 2.6e-09 36.6 0.0 0.001 18.8 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat PC_rep PF01851.17 EPR78418.1 - 7.2e-06 25.9 8.2 0.15 12.3 0.0 6.5 7 1 0 8 8 8 2 Proteasome/cyclosome repeat Beta-lactamase2 PF13354.1 EPR78418.1 - 0.03 13.7 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase enzyme family Pox_A14 PF05767.7 EPR78419.1 - 0.0074 16.2 0.4 0.0074 16.2 0.3 3.8 4 1 0 4 4 4 1 Poxvirus virion envelope protein A14 LRR_4 PF12799.2 EPR78420.1 - 3.7e-32 109.4 78.8 2.7e-09 36.4 7.3 7.6 2 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78420.1 - 1.4e-27 95.2 40.9 1.1e-07 31.5 0.8 5.7 3 2 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EPR78420.1 - 5.2e-18 62.3 40.7 0.0026 17.5 0.4 10.8 11 1 0 11 11 11 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR78420.1 - 1.5e-12 45.5 32.8 0.053 13.7 0.2 10.5 12 0 0 12 12 12 5 Leucine rich repeat LRR_9 PF14580.1 EPR78420.1 - 3.6e-09 36.4 18.9 7.3e-06 25.6 2.4 3.6 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 EPR78420.1 - 4.1e-06 26.3 46.7 0.024 14.6 0.7 9.7 11 1 0 11 11 11 4 Leucine Rich repeat LRR_5 PF13306.1 EPR78420.1 - 0.0018 17.9 10.3 0.063 12.9 1.0 2.7 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) Sec23_helical PF04815.10 EPR78420.1 - 0.11 11.8 1.5 0.38 10.1 0.0 2.5 2 1 0 2 2 2 0 Sec23/Sec24 helical domain zf-SNAP50_C PF12251.3 EPR78420.1 - 0.13 11.6 1.1 0.55 9.5 0.1 2.2 2 1 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Laminin_II PF06009.7 EPR78420.1 - 0.33 10.6 2.1 0.43 10.3 0.1 2.3 2 2 0 2 2 2 0 Laminin Domain II Rep_fac-A_3 PF08661.6 EPR78421.1 - 2.6e-10 40.1 0.6 2.9e-10 40.0 0.4 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 UCH PF00443.24 EPR78422.1 - 9.4e-23 80.6 15.3 1.2e-22 80.2 10.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Casein_kappa PF00997.13 EPR78422.1 - 2.2 7.9 9.0 0.13 11.9 1.8 2.1 2 1 0 2 2 2 0 Kappa casein UCH PF00443.24 EPR78424.1 - 3e-24 85.5 19.3 4.9e-24 84.8 13.4 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78424.1 - 8.8e-07 28.6 6.2 0.00039 19.9 1.8 3.5 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase E6 PF00518.12 EPR78424.1 - 0.028 14.7 0.9 0.1 12.9 0.2 2.2 2 0 0 2 2 2 0 Early Protein (E6) DUF3583 PF12126.3 EPR78426.1 - 0.1 11.6 0.3 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) zf-BED PF02892.10 EPR78426.1 - 1.6 8.5 4.8 12 5.7 0.5 2.5 2 0 0 2 2 2 0 BED zinc finger Peptidase_S24 PF00717.18 EPR78427.1 - 2.6e-11 43.0 0.2 3.8e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like bZIP_1 PF00170.16 EPR78428.1 - 3.5e-08 33.2 14.3 3.5e-08 33.2 9.9 2.5 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPR78428.1 - 4.6e-08 32.7 14.6 4.6e-08 32.7 10.1 3.1 1 1 2 3 3 3 2 Basic region leucine zipper Mei4 PF13971.1 EPR78428.1 - 0.002 17.1 6.7 0.0024 16.8 4.7 1.1 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Seadorna_VP6 PF07407.6 EPR78428.1 - 0.0038 16.0 3.1 0.0042 15.9 2.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP6 protein Rab5-bind PF09311.6 EPR78428.1 - 0.021 14.7 12.5 0.025 14.4 8.7 1.1 1 0 0 1 1 1 0 Rabaptin-like protein HCR PF07111.7 EPR78428.1 - 0.021 12.8 6.8 0.023 12.7 4.7 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Mnd1 PF03962.10 EPR78428.1 - 0.023 14.3 11.8 0.027 14.1 8.2 1.1 1 0 0 1 1 1 0 Mnd1 family MAD PF05557.8 EPR78428.1 - 0.04 12.0 15.6 0.06 11.4 10.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein HOOK PF05622.7 EPR78428.1 - 0.042 11.6 12.8 0.048 11.4 8.9 1.0 1 0 0 1 1 1 0 HOOK protein TSC22 PF01166.13 EPR78428.1 - 0.054 13.4 18.5 0.13 12.2 0.4 3.4 1 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 EPR78428.1 - 0.056 13.7 13.2 0.051 13.8 6.1 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF3552 PF12072.3 EPR78428.1 - 0.074 12.2 18.9 0.098 11.8 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Mod_r PF07200.8 EPR78428.1 - 0.074 12.9 13.8 0.093 12.6 9.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 EPR78428.1 - 0.1 12.1 20.7 0.068 12.6 6.3 2.6 1 1 2 3 3 3 0 Septum formation initiator Ax_dynein_light PF10211.4 EPR78428.1 - 0.12 12.1 17.0 0.16 11.7 11.8 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain Phage_GP20 PF06810.6 EPR78428.1 - 0.19 11.1 18.4 0.23 10.8 12.7 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF848 PF05852.6 EPR78428.1 - 0.28 11.0 10.7 0.34 10.7 7.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) APG6 PF04111.7 EPR78428.1 - 0.35 9.8 15.3 0.45 9.5 10.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1317 PF07026.6 EPR78428.1 - 0.39 10.6 1.7 0.75 9.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) Tnp_P_element PF12017.3 EPR78428.1 - 0.44 9.7 10.5 0.3 10.3 1.2 2.0 1 1 1 2 2 2 0 Transposase protein DUF1465 PF07323.7 EPR78428.1 - 0.74 9.3 5.6 1.7 8.2 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) CCDC155 PF14662.1 EPR78428.1 - 0.88 9.1 18.8 2 7.9 13.0 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 EPR78428.1 - 0.9 9.3 26.2 2.3 8.0 12.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD PF14073.1 EPR78428.1 - 1 9.1 19.3 37 4.0 13.4 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 V_ATPase_I PF01496.14 EPR78428.1 - 1.1 7.0 10.5 1.3 6.7 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Chibby PF14645.1 EPR78428.1 - 1.4 8.7 12.0 0.89 9.4 6.5 2.0 1 1 1 2 2 2 0 Chibby family BLOC1_2 PF10046.4 EPR78428.1 - 1.5 9.0 16.4 4.2 7.5 11.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AKNA PF12443.3 EPR78428.1 - 1.6 8.7 13.4 0.24 11.4 3.1 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor Viral_P18 PF04521.8 EPR78428.1 - 1.9 7.9 11.0 6.9 6.1 1.6 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein AAA_23 PF13476.1 EPR78428.1 - 2 8.6 23.2 3 8.0 16.1 1.3 1 0 0 1 1 1 0 AAA domain DUF737 PF05300.6 EPR78428.1 - 2.4 8.0 14.4 0.33 10.9 6.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Med9 PF07544.8 EPR78428.1 - 2.5 7.8 15.3 69 3.2 10.6 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF724 PF05266.9 EPR78428.1 - 2.9 7.4 13.4 4.4 6.8 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YlqD PF11068.3 EPR78428.1 - 3.1 7.8 15.0 0.49 10.4 6.4 1.9 1 1 1 2 2 2 0 YlqD protein MerR-DNA-bind PF09278.6 EPR78428.1 - 3.8 7.9 9.9 8.1 6.9 2.0 2.7 1 1 1 2 2 2 0 MerR, DNA binding Bud13 PF09736.4 EPR78428.1 - 4.3 7.6 10.5 5.2 7.3 7.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NUDE_C PF04880.8 EPR78428.1 - 5.7 7.2 8.7 2.8 8.2 4.8 1.5 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Laminin_II PF06009.7 EPR78428.1 - 5.7 6.6 12.7 2.9 7.6 5.4 1.9 1 1 0 1 1 1 0 Laminin Domain II MRF_C1 PF13887.1 EPR78428.1 - 5.8 6.0 7.9 12 5.0 0.4 3.1 2 1 1 3 3 3 0 Myelin gene regulatory factor -C-terminal domain 1 DUF342 PF03961.8 EPR78428.1 - 6.3 5.0 15.3 7.3 4.8 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fzo_mitofusin PF04799.8 EPR78428.1 - 6.3 6.1 11.7 2.9 7.2 5.3 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF4200 PF13863.1 EPR78428.1 - 7 6.6 24.5 1.6 8.7 8.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EPR78428.1 - 7.5 6.9 15.3 78 3.6 10.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 EPR78428.1 - 7.8 6.5 18.9 5.3 7.1 1.4 2.7 1 1 2 3 3 3 0 DivIVA protein IFP_35_N PF07334.8 EPR78428.1 - 8.4 6.4 17.1 16 5.5 1.8 2.5 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1136 PF06582.7 EPR78428.1 - 8.7 6.1 14.0 17 5.2 0.8 3.6 3 0 0 3 3 3 0 Repeat of unknown function (DUF1136) DUF3287 PF11690.3 EPR78428.1 - 9.8 6.2 7.6 25 4.9 5.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Acetyltransf_7 PF13508.1 EPR78429.1 - 1.3e-06 28.4 1.3 1.6e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-C2H2_3 PF13878.1 EPR78429.1 - 3.2e-06 26.5 0.5 5.7e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EPR78429.1 - 3.1e-05 23.9 0.0 4.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EPR78429.1 - 7.6e-05 22.8 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPR78429.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Epiglycanin_C PF14654.1 EPR78430.1 - 0.011 15.6 0.5 0.017 15.1 0.3 1.2 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region DUF2909 PF11137.3 EPR78430.1 - 0.053 13.2 0.7 0.085 12.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DUF576 PF04507.7 EPR78430.1 - 0.054 12.4 1.1 0.069 12.0 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF576 TarH PF02203.10 EPR78430.1 - 0.089 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue Spt20 PF12090.3 EPR78431.1 - 0.21 10.9 9.4 0.33 10.2 0.6 2.2 1 1 0 2 2 2 0 Spt20 family RhoGAP PF00620.22 EPR78433.1 - 1.1e-16 60.7 0.2 2e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain zf-CCCH PF00642.19 EPR78434.1 - 0.014 15.0 2.7 0.025 14.2 1.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPR78434.1 - 0.032 14.2 4.7 0.059 13.3 3.2 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUSP PF06337.7 EPR78435.1 - 7.9 6.9 9.6 11 6.4 6.5 1.4 1 1 0 1 1 1 0 DUSP domain DUF359 PF04019.7 EPR78436.1 - 0.032 13.6 5.1 0.31 10.4 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF359) VID27 PF08553.5 EPR78437.1 - 5.4e-25 87.7 72.1 2e-22 79.2 50.0 3.4 1 1 0 1 1 1 1 VID27 cytoplasmic protein MiaE PF06175.6 EPR78437.1 - 0.023 14.0 1.9 0.051 12.9 1.3 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) YIF1 PF03878.10 EPR78440.1 - 2.1e-14 53.3 13.6 1.1e-13 50.9 9.4 1.8 1 1 0 1 1 1 1 YIF1 Tmemb_185A PF10269.4 EPR78440.1 - 0.031 13.8 1.4 0.036 13.6 1.0 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Mpp10 PF04006.7 EPR78442.1 - 5.1e-09 35.0 10.7 5.1e-09 35.0 7.4 1.7 1 1 0 1 1 1 1 Mpp10 protein DNAPolymera_Pol PF11590.3 EPR78442.1 - 0.069 12.8 0.2 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol DUF2862 PF11061.3 EPR78442.1 - 0.073 12.7 3.1 8.7 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) Vmethyltransf_C PF08456.5 EPR78442.1 - 0.09 12.1 7.9 0.32 10.3 2.4 2.3 1 1 1 2 2 2 0 Viral methyltransferase C-terminal DUF885 PF05960.6 EPR78443.1 - 0.017 14.2 0.2 0.03 13.5 0.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) BRX_N PF13713.1 EPR78443.1 - 0.095 12.1 0.4 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Tn7_Tnp_TnsA_C PF08721.6 EPR78443.1 - 2 8.5 8.9 0.91 9.5 0.2 3.6 3 1 1 4 4 4 0 TnsA endonuclease C terminal Baculo_PEP_C PF04513.7 EPR78443.1 - 2.9 7.7 5.6 0.87 9.3 0.6 2.5 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acyltransferase PF01553.16 EPR78448.1 - 1.3e-13 50.4 0.1 2.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase LRR_4 PF12799.2 EPR78450.1 - 2.1e-10 39.9 17.1 1.7e-06 27.5 3.3 7.7 6 1 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78450.1 - 0.095 12.7 0.3 0.095 12.7 0.2 9.4 7 3 0 7 7 7 0 Leucine Rich Repeat SpoU_sub_bind PF08032.7 EPR78451.1 - 0.15 12.2 0.6 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DDE_Tnp_IS1595 PF12762.2 EPR78453.1 - 1.3e-05 25.0 0.0 1.5e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF912 PF06024.7 EPR78454.1 - 0.29 11.2 5.5 0.3 11.1 1.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) BING4CT PF08149.6 EPR78455.1 - 0.15 11.5 2.0 17 5.0 0.1 2.9 2 0 0 2 2 2 0 BING4CT (NUC141) domain LisH PF08513.6 EPR78456.1 - 7.9e-06 25.4 0.0 1.7e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 LisH Na_H_Exchanger PF00999.16 EPR78457.1 - 1.6e-39 135.5 38.0 2e-39 135.2 26.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TBP PF00352.16 EPR78458.1 - 2.1e-68 225.6 0.5 1.8e-33 113.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EPR78458.1 - 1.2e-05 25.3 0.1 0.23 11.5 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.1 EPR78458.1 - 0.18 11.4 4.5 1.8 8.2 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4295) DUF3925 PF13063.1 EPR78459.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) PC_rep PF01851.17 EPR78460.1 - 1e-14 53.7 7.6 0.0058 16.7 0.1 6.7 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPR78460.1 - 6.1e-14 52.0 0.0 0.0021 18.2 0.0 3.5 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EPR78460.1 - 5.2e-05 23.6 0.0 0.27 11.7 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EPR78460.1 - 0.019 15.0 0.0 20 5.5 0.1 5.0 5 0 0 5 5 5 0 HEAT repeat DUF3596 PF12167.3 EPR78460.1 - 0.09 12.3 0.1 1.3 8.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) Helicase_C_3 PF13625.1 EPR78461.1 - 7.6e-25 87.1 0.0 2.2e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR78461.1 - 3.5e-17 62.8 0.2 9.1e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPR78461.1 - 6.2e-12 45.2 0.2 3.6e-11 42.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPR78461.1 - 1.2e-11 43.9 0.3 4.8e-11 42.0 0.1 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.24 EPR78461.1 - 6.1e-07 29.0 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EPR78461.1 - 0.12 11.1 0.0 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Ribosomal_L1 PF00687.16 EPR78462.1 - 6.3e-19 68.2 7.9 7.7e-19 67.9 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family BH4 PF02180.12 EPR78463.1 - 0.062 12.7 0.6 0.21 11.1 0.4 2.0 1 0 0 1 1 1 0 Bcl-2 homology region 4 Dus PF01207.12 EPR78464.1 - 1.9e-45 155.0 0.0 2.4e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ras PF00071.17 EPR78465.1 - 3.8e-39 133.6 0.1 4.8e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR78465.1 - 1.1e-18 67.8 0.0 1.8e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPR78465.1 - 3.6e-12 45.8 0.2 5.1e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPR78465.1 - 0.00011 22.1 0.1 0.00017 21.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPR78465.1 - 0.00023 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPR78465.1 - 0.00054 19.1 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.10 EPR78465.1 - 0.00077 19.2 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 NTPase AAA PF00004.24 EPR78465.1 - 0.00084 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPR78465.1 - 0.0044 17.1 0.2 0.017 15.2 0.2 1.9 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EPR78465.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EPR78465.1 - 0.02 14.4 0.3 2.5 7.5 0.1 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1500 PF07389.7 EPR78465.1 - 0.024 14.6 0.1 0.047 13.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) NACHT PF05729.7 EPR78465.1 - 0.025 14.2 0.1 0.084 12.5 0.0 1.9 3 0 0 3 3 2 0 NACHT domain AAA_18 PF13238.1 EPR78465.1 - 0.035 14.4 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPR78465.1 - 0.042 13.8 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EPR78465.1 - 0.05 12.2 0.2 0.8 8.3 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 EPR78465.1 - 0.059 12.8 0.1 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2201 PF09967.4 EPR78465.1 - 0.059 13.3 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 VWA-like domain (DUF2201) AAA_24 PF13479.1 EPR78465.1 - 0.067 12.7 0.4 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPR78465.1 - 0.069 12.8 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPR78465.1 - 0.091 12.6 0.1 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Cytochrom_D1 PF02239.11 EPR78465.1 - 0.093 11.0 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain AAA_16 PF13191.1 EPR78465.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain DEAD PF00270.24 EPR78466.1 - 5.3e-32 110.6 0.0 1.1e-31 109.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR78466.1 - 1.2e-19 69.8 3.5 2.9e-18 65.5 2.4 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SKIP_SNW PF02731.10 EPR78467.1 - 0.0018 17.7 10.8 0.0029 17.0 7.5 1.4 1 1 0 1 1 1 1 SKIP/SNW domain Fib_alpha PF08702.5 EPR78467.1 - 6.6 6.8 9.9 0.42 10.7 0.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_7 PF13499.1 EPR78468.1 - 0.064 13.4 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair UCH PF00443.24 EPR78468.1 - 0.12 11.4 1.5 0.16 11.0 1.0 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AF0941-like PF14591.1 EPR78468.1 - 0.63 10.1 6.7 0.71 9.9 1.9 2.6 2 1 0 2 2 2 0 AF0941-like DUF848 PF05852.6 EPR78468.1 - 1.4 8.7 4.5 1 9.2 0.2 2.4 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) LRR_4 PF12799.2 EPR78469.1 - 3.3e-19 68.0 32.0 5.6e-06 25.8 0.9 6.1 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78469.1 - 7.2e-17 60.8 29.9 1.4e-07 31.1 2.4 4.5 2 2 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EPR78469.1 - 5.2e-10 37.9 30.2 0.42 10.8 0.1 8.8 8 1 1 9 9 9 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR78469.1 - 4.2e-06 26.0 24.5 3.6 8.2 0.0 8.4 8 1 0 8 8 8 4 Leucine rich repeat LRR_6 PF13516.1 EPR78469.1 - 0.22 11.6 27.8 2 8.7 0.1 7.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_3 PF07725.7 EPR78469.1 - 9.3 6.2 7.8 8.6 6.3 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat ThiF PF00899.16 EPR78470.1 - 9.1e-24 83.8 2.0 2.2e-23 82.6 0.1 2.5 2 1 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.4 EPR78470.1 - 1.2e-12 46.9 3.8 3.1e-12 45.6 2.7 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 EPR78470.1 - 8.2e-12 44.5 0.6 2.4e-11 43.0 0.4 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein NAD_binding_7 PF13241.1 EPR78470.1 - 4.3e-05 23.7 0.0 0.0002 21.5 0.0 2.1 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EPR78470.1 - 0.00065 19.8 0.1 0.00065 19.8 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF2180 PF09947.4 EPR78470.1 - 0.0063 16.2 1.2 0.02 14.6 0.8 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) TrkA_N PF02254.13 EPR78470.1 - 0.013 15.4 0.3 0.093 12.7 0.2 2.4 1 1 1 2 2 2 0 TrkA-N domain Saccharop_dh PF03435.13 EPR78470.1 - 0.02 13.8 0.0 0.035 13.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Neur_chan_memb PF02932.11 EPR78470.1 - 3.1 7.6 10.1 5.8 6.7 7.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YcxB PF14317.1 EPR78471.1 - 0.019 14.1 1.7 0.047 12.9 1.2 1.7 1 0 0 1 1 1 0 YcxB-like protein PH PF00169.24 EPR78471.1 - 0.037 14.2 0.2 0.046 13.9 0.2 1.3 1 1 0 1 1 1 0 PH domain TIR PF01582.15 EPR78471.1 - 0.53 9.7 3.7 7.5 5.9 0.2 2.3 2 1 0 2 2 2 0 TIR domain Mannosyl_trans2 PF04188.8 EPR78472.1 - 3.9e-22 78.8 32.3 1.6e-15 56.9 16.3 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) Tyr_Deacylase PF02580.11 EPR78473.1 - 2.5e-39 134.5 0.0 2.8e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase C2 PF00168.25 EPR78474.1 - 2.4e-23 81.7 0.2 4.2e-19 68.1 0.1 3.1 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 EPR78474.1 - 0.00021 21.3 0.0 0.00068 19.7 0.0 1.9 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1097 PF06496.6 EPR78474.1 - 0.1 12.4 0.1 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) UQ_con PF00179.21 EPR78475.1 - 2.9e-42 143.4 0.0 3.3e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPR78475.1 - 7.3e-07 29.0 0.0 8.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPR78475.1 - 0.018 14.9 0.1 0.02 14.8 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EPR78475.1 - 0.032 13.9 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain POP1 PF06978.6 EPR78478.1 - 8.1e-17 61.4 13.8 8.1e-17 61.4 9.6 1.3 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 DAN PF03045.10 EPR78478.1 - 0.01 15.2 2.5 0.12 11.7 0.4 2.4 2 0 0 2 2 2 0 DAN domain DLD PF14878.1 EPR78479.1 - 0.063 13.3 0.1 0.063 13.3 0.0 2.9 3 1 0 3 3 3 0 Death-like domain of SPT6 Ribosomal_L37ae PF01780.14 EPR78480.1 - 1.4e-17 63.3 4.0 1.5e-17 63.1 2.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-FCS PF06467.9 EPR78480.1 - 0.0047 16.5 3.7 0.26 10.9 0.5 2.2 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EPR78480.1 - 0.0055 16.9 4.9 0.066 13.5 1.5 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C4_ClpX PF06689.8 EPR78480.1 - 0.017 14.6 7.4 0.053 13.0 0.6 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-BED PF02892.10 EPR78480.1 - 0.043 13.5 9.2 0.074 12.8 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.1 EPR78480.1 - 0.1 12.9 4.7 2.9 8.4 1.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 EPR78480.1 - 0.24 10.6 4.6 4.5 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC5 PF06221.8 EPR78480.1 - 0.35 10.6 5.2 0.94 9.2 2.3 2.0 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type Zn-ribbon_8 PF09723.5 EPR78480.1 - 0.35 10.8 3.8 3 7.8 0.8 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EPR78480.1 - 0.35 10.3 4.1 4.7 6.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.6 EPR78480.1 - 0.54 9.6 5.5 1 8.7 0.0 2.5 2 1 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-Sec23_Sec24 PF04810.10 EPR78480.1 - 0.61 9.6 10.2 3.2 7.3 0.6 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger DUF2757 PF10955.3 EPR78480.1 - 0.68 10.1 3.5 1 9.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) CarbpepA_inh PF02977.10 EPR78480.1 - 1.1 8.8 6.9 16 5.1 4.8 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor A2L_zn_ribbon PF08792.5 EPR78480.1 - 1.3 8.5 6.1 4.5 6.8 1.4 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF2175 PF09943.4 EPR78480.1 - 1.3 9.1 5.4 3.8 7.6 0.2 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) C1_2 PF03107.11 EPR78480.1 - 1.5 9.0 7.4 3 8.0 0.4 2.3 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.17 EPR78480.1 - 2.1 8.1 6.6 3.1 7.5 4.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 EPR78480.1 - 4.5 7.0 7.4 1.7 8.3 2.8 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PyrI_C PF02748.10 EPR78480.1 - 5.9 6.4 6.7 8.8 5.8 1.2 2.5 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2688 PF10892.3 EPR78480.1 - 9.7 5.9 6.5 3 7.5 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) Lipase_3 PF01764.20 EPR78482.1 - 0.065 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF3730 PF12530.3 EPR78483.1 - 0.048 13.5 3.3 0.11 12.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) RRM_1 PF00076.17 EPR78484.1 - 1.1e-57 191.5 12.0 1.2e-15 56.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR78484.1 - 1.4e-41 140.2 2.8 5.7e-12 45.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR78484.1 - 9.3e-29 99.0 8.2 2.2e-09 37.0 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPR78484.1 - 1.2e-07 31.3 0.7 0.03 14.0 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EPR78484.1 - 0.0036 17.0 0.5 3 7.6 0.0 3.7 3 1 0 3 3 3 2 Limkain b1 PABP PF00658.13 EPR78484.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain PHD PF00628.24 EPR78485.1 - 1.3e-08 34.3 5.7 2.1e-08 33.7 3.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EPR78485.1 - 0.0094 16.0 0.6 0.0094 16.0 0.4 1.9 2 1 0 2 2 2 1 PHD-like zinc-binding domain DUF4490 PF14892.1 EPR78485.1 - 0.027 14.1 0.8 0.034 13.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4490) Asp23 PF03780.8 EPR78485.1 - 0.029 14.6 1.0 0.044 14.0 0.7 1.3 1 0 0 1 1 1 0 Asp23 family Xpo1 PF08389.7 EPR78485.1 - 0.03 14.2 0.6 0.046 13.6 0.4 1.3 1 0 0 1 1 1 0 Exportin 1-like protein zf-Sec23_Sec24 PF04810.10 EPR78485.1 - 0.044 13.3 0.3 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ING PF12998.2 EPR78485.1 - 0.049 13.9 6.1 0.12 12.6 4.3 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Pox_A_type_inc PF04508.7 EPR78485.1 - 0.057 13.2 0.9 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Lipoprotein_20 PF13942.1 EPR78485.1 - 0.086 12.3 1.9 0.12 11.9 1.3 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Aida_N PF08910.5 EPR78485.1 - 0.11 12.6 2.2 0.51 10.5 0.9 2.0 2 0 0 2 2 2 0 Aida N-terminus Snapin_Pallidin PF14712.1 EPR78485.1 - 1.8 8.9 7.4 4.3 7.7 1.0 2.3 1 1 1 2 2 2 0 Snapin/Pallidin DnaJ PF00226.26 EPR78486.1 - 2.7e-19 68.6 2.4 2.7e-19 68.6 1.7 2.3 2 0 0 2 2 2 1 DnaJ domain Copper-bind PF00127.15 EPR78486.1 - 0.12 12.5 1.5 2.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family ABC2_membrane_3 PF12698.2 EPR78486.1 - 1.8 7.5 13.3 2.8 6.8 9.2 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Ribosomal_60s PF00428.14 EPR78487.1 - 4.8e-09 36.5 6.6 6e-09 36.1 4.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rep_fac_C PF08542.6 EPR78488.1 - 2e-15 56.5 0.5 2e-15 56.5 0.4 2.9 4 0 0 4 4 4 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPR78488.1 - 1.3e-11 44.4 4.9 1.3e-11 44.4 3.4 1.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 EPR78488.1 - 9.5e-09 34.9 1.5 9.5e-09 34.9 1.0 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EPR78488.1 - 7.9e-05 22.8 1.1 0.00015 21.9 0.2 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPR78488.1 - 0.00012 22.3 2.2 0.00017 21.9 0.2 2.1 2 0 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EPR78488.1 - 0.002 18.1 1.3 0.15 12.0 0.2 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EPR78488.1 - 0.002 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.24 EPR78488.1 - 0.0029 17.8 1.9 0.0029 17.8 1.3 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPR78488.1 - 0.017 14.8 0.4 0.05 13.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPR78488.1 - 0.018 15.0 0.2 0.18 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EPR78488.1 - 0.024 14.0 0.1 0.03 13.7 0.1 1.3 1 1 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EPR78488.1 - 0.068 13.0 7.2 0.052 13.4 2.0 2.8 1 1 1 2 2 2 0 AAA domain DUF3278 PF11683.3 EPR78489.1 - 6 6.8 10.8 0.68 9.9 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) LRR_4 PF12799.2 EPR78492.1 - 1.2e-31 107.8 66.3 6.4e-08 32.0 0.1 6.8 4 2 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78492.1 - 4.2e-23 80.8 33.8 2.5e-08 33.5 1.8 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EPR78492.1 - 3.9e-14 50.5 41.7 0.063 13.3 0.0 9.9 9 1 1 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR78492.1 - 6.2e-12 43.6 27.7 1.4 9.4 0.0 9.7 11 0 0 11 11 11 6 Leucine rich repeat LRR_6 PF13516.1 EPR78492.1 - 2.5e-08 33.1 34.5 0.011 15.7 0.1 8.7 8 1 1 9 9 9 4 Leucine Rich repeat CBFD_NFYB_HMF PF00808.18 EPR78493.1 - 9.1e-18 64.0 0.4 1.4e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR78493.1 - 8.3e-09 35.4 0.2 1.4e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 T_Ag_DNA_bind PF02217.11 EPR78494.1 - 0.0023 18.3 1.8 0.005 17.1 1.2 1.6 1 0 0 1 1 1 1 Origin of replication binding protein Tissue_fac PF01108.12 EPR78495.1 - 0.16 11.7 0.6 0.27 10.9 0.4 1.3 1 0 0 1 1 1 0 Tissue factor LSM PF01423.17 EPR78496.1 - 1.6e-10 40.3 3.7 3.2e-10 39.4 2.6 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPR78496.1 - 0.0038 17.1 1.1 0.0041 16.9 0.0 1.6 2 0 0 2 2 2 1 Ataxin 2 SM domain RSD-2 PF07547.8 EPR78497.1 - 0.092 12.9 0.3 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 RSD-2 N-terminal domain MTS PF05175.9 EPR78498.1 - 1.3e-10 40.9 0.0 1.9e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EPR78498.1 - 5.8e-08 32.4 0.7 1.3e-07 31.3 0.5 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPR78498.1 - 2.4e-06 27.5 0.0 5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPR78498.1 - 4.3e-05 23.9 0.0 7.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPR78498.1 - 0.0012 19.3 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR78498.1 - 0.0026 18.3 0.0 0.0035 17.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPR78498.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPR78498.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EPR78498.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Eco57I PF07669.6 EPR78498.1 - 0.016 15.5 0.5 0.032 14.5 0.0 1.8 2 1 0 2 2 2 0 Eco57I restriction-modification methylase Methyltransf_23 PF13489.1 EPR78498.1 - 0.03 14.0 0.0 0.033 13.9 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EPR78498.1 - 0.073 12.1 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sec10 PF07393.6 EPR78499.1 - 2.2e-10 39.4 31.6 7.8e-10 37.5 11.3 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec10 CHD5 PF04420.9 EPR78499.1 - 0.021 14.5 0.7 0.021 14.5 0.5 2.7 2 0 0 2 2 2 0 CHD5-like protein W2 PF02020.13 EPR78499.1 - 0.058 13.3 6.6 0.025 14.5 1.5 2.7 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Helicase_C PF00271.26 EPR78500.1 - 2.5e-12 46.4 0.0 8.3e-12 44.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPR78500.1 - 1.1e-11 44.5 0.2 2.7e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPR78500.1 - 1.1e-11 44.6 2.5 1.5e-11 44.2 0.2 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 EPR78500.1 - 2.1e-11 43.6 0.7 1.7e-10 40.6 0.1 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.1 EPR78500.1 - 1.6e-06 28.4 11.7 2.9e-05 24.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.9 EPR78500.1 - 7.5e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_14 PF13173.1 EPR78500.1 - 8.5e-06 25.6 1.8 8.5e-06 25.6 1.3 3.9 2 2 1 3 3 3 1 AAA domain Helicase_RecD PF05127.9 EPR78500.1 - 1.1e-05 25.0 0.4 6.8e-05 22.5 0.0 2.4 3 0 0 3 3 2 1 Helicase ResIII PF04851.10 EPR78500.1 - 1.2e-05 25.2 0.3 1.2e-05 25.2 0.2 3.7 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EPR78500.1 - 8.4e-05 21.6 0.2 0.00023 20.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein SMC_N PF02463.14 EPR78500.1 - 9.5e-05 21.7 0.6 0.00035 19.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPR78500.1 - 0.00018 20.9 0.0 0.00049 19.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EPR78500.1 - 0.00041 20.5 0.7 0.2 11.8 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPR78500.1 - 0.0019 17.4 0.0 0.0045 16.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPR78500.1 - 0.0019 18.3 0.0 0.0062 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPR78500.1 - 0.0052 16.3 0.1 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EPR78500.1 - 0.0083 16.4 6.6 0.026 14.8 3.2 2.7 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.7 EPR78500.1 - 0.0095 15.0 0.0 0.027 13.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Miro PF08477.8 EPR78500.1 - 0.017 15.6 0.8 0.061 13.8 0.1 2.4 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 EPR78500.1 - 0.017 14.5 0.3 0.11 11.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EPR78500.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EPR78500.1 - 0.028 13.6 0.5 0.099 11.8 0.1 2.3 2 1 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 EPR78500.1 - 0.034 13.7 9.3 0.033 13.7 3.3 3.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EPR78500.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPR78500.1 - 0.13 12.6 44.0 2e+02 2.1 30.5 3.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPR78500.1 - 0.14 12.1 0.2 2.7 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EPR78500.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain LEDGF PF11467.3 EPR78500.1 - 0.79 9.4 8.8 0.12 12.0 0.4 2.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) zf-DHHC PF01529.15 EPR78501.1 - 4e-29 101.2 18.9 4e-29 101.2 13.1 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase Flag1_repress PF03614.8 EPR78501.1 - 0.05 13.1 0.5 0.092 12.2 0.4 1.4 1 0 0 1 1 1 0 Repressor of phase-1 flagellin PMP22_Claudin PF00822.15 EPR78501.1 - 2.6 7.6 8.0 0.75 9.4 0.6 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family zf-H2C2_2 PF13465.1 EPR78502.1 - 8.5e-06 25.8 0.6 8.5e-06 25.8 0.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EPR78502.1 - 2.5e-05 24.3 0.8 2.5e-05 24.3 0.6 3.9 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPR78502.1 - 6.2e-05 23.0 11.2 0.00021 21.3 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPR78502.1 - 0.00039 20.4 1.5 0.0013 18.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPR78502.1 - 0.018 15.2 0.5 0.018 15.2 0.4 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type XendoU PF09412.5 EPR78502.1 - 0.073 12.0 1.4 0.13 11.3 0.8 1.4 1 1 0 2 2 2 0 Endoribonuclease XendoU zf-C2H2_2 PF12756.2 EPR78502.1 - 0.76 9.9 8.6 1.8 8.7 4.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DnaJ PF00226.26 EPR78504.1 - 1.5e-06 27.8 0.2 2.3e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EPR78504.1 - 0.07 12.6 8.2 0.98 8.9 5.7 2.4 1 1 0 1 1 1 0 CSL zinc finger Rota_Capsid_VP6 PF00980.12 EPR78504.1 - 0.088 11.4 3.0 0.1 11.1 2.1 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 SusD-like_3 PF14322.1 EPR78504.1 - 0.84 9.6 4.6 1 9.3 3.2 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DUF2404 PF10296.4 EPR78505.1 - 0.082 13.0 0.2 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Oscp1 PF10188.4 EPR78505.1 - 0.085 12.6 4.9 0.052 13.3 1.7 1.7 2 1 0 2 2 2 0 Organic solute transport protein 1 FYRN PF05964.9 EPR78506.1 - 7.7e-12 44.4 0.8 7.2e-10 38.1 0.1 2.3 2 0 0 2 2 2 2 F/Y-rich N-terminus FYRC PF05965.9 EPR78506.1 - 0.0039 16.9 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus DnaJ PF00226.26 EPR78507.1 - 1e-18 66.7 0.4 1.9e-18 65.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain PCNA_N PF00705.13 EPR78508.1 - 5.1e-23 80.9 1.0 5.1e-23 80.9 0.7 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EPR78508.1 - 1.6e-11 44.2 2.6 1.9e-05 24.5 0.2 3.2 2 1 1 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EPR78508.1 - 6.1e-06 25.5 1.0 8.3e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EPR78508.1 - 8.8e-06 24.6 1.9 0.00014 20.7 1.3 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 EPR78508.1 - 0.009 14.9 0.8 0.031 13.2 0.7 2.0 1 1 0 1 1 1 1 Hus1-like protein LRR_8 PF13855.1 EPR78509.1 - 3e-06 26.8 31.0 0.008 15.9 0.2 6.9 5 2 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.2 EPR78509.1 - 0.014 14.9 0.1 0.014 14.9 0.0 9.1 7 2 3 10 10 10 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78509.1 - 0.091 12.8 22.4 12 6.4 0.1 8.7 6 1 1 7 7 7 0 Leucine Rich Repeat Sirohm_synth_M PF14824.1 EPR78509.1 - 2 7.4 5.2 15 4.6 1.2 3.0 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central Sec7 PF01369.15 EPR78510.1 - 1.4e-40 139.0 16.0 4.4e-40 137.3 11.1 1.8 1 0 0 1 1 1 1 Sec7 domain DWNN PF08783.6 EPR78511.1 - 1.2e-21 76.3 0.3 2.9e-21 75.1 0.2 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EPR78511.1 - 9.1e-07 28.2 3.3 1.8e-06 27.3 2.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_5 PF14634.1 EPR78511.1 - 0.00027 20.6 14.6 0.00027 20.6 10.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPR78511.1 - 0.00034 20.5 9.5 0.00034 20.5 6.6 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPR78511.1 - 0.001 18.8 7.4 0.001 18.8 5.1 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCHC PF00098.18 EPR78511.1 - 0.0044 16.8 3.4 0.012 15.4 2.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.1 EPR78511.1 - 0.0081 15.9 7.7 0.018 14.8 5.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Siva PF05458.7 EPR78511.1 - 0.02 14.4 2.8 0.032 13.8 2.0 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-C3HC4_3 PF13920.1 EPR78511.1 - 0.51 10.0 19.4 0.036 13.7 9.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPR78511.1 - 0.66 9.7 7.5 1.7 8.4 3.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EPR78511.1 - 0.71 9.5 15.0 0.036 13.7 5.5 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_L_2 PF13656.1 EPR78512.1 - 2e-21 75.2 0.2 2.5e-21 74.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPR78512.1 - 0.08 12.0 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain 6PGD PF00393.14 EPR78513.1 - 6.9e-85 284.7 2.1 8.8e-85 284.4 1.4 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPR78513.1 - 5.4e-43 146.6 0.0 9.3e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPR78513.1 - 0.0024 18.2 0.0 0.0055 17.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EPR78513.1 - 0.0065 16.5 0.0 0.062 13.4 0.0 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase B PF02216.11 EPR78513.1 - 0.14 11.9 1.2 0.34 10.6 0.3 2.0 2 0 0 2 2 2 0 B domain DUF4156 PF13698.1 EPR78514.1 - 6.4 6.7 8.4 3.4 7.6 0.3 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4156) UCH PF00443.24 EPR78515.1 - 2.3e-06 26.9 6.3 0.00018 20.7 4.4 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78515.1 - 0.067 12.6 1.1 2.5 7.4 0.0 2.4 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Plus-3 PF03126.13 EPR78515.1 - 0.98 9.4 5.2 0.88 9.6 0.2 2.3 2 0 0 2 2 2 0 Plus-3 domain Polysacc_deac_1 PF01522.16 EPR78516.1 - 1.9e-20 72.6 0.1 3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Trp_syntA PF00290.15 EPR78516.1 - 0.13 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain CTP_synth_N PF06418.9 EPR78518.1 - 8.9e-98 326.7 5.1 1.3e-97 326.2 3.5 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EPR78518.1 - 2.4e-46 157.6 0.1 4.9e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPR78518.1 - 3.8e-08 33.0 0.1 2.4e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 EPR78518.1 - 0.075 12.6 0.1 0.21 11.1 0.1 1.8 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Calx-beta PF03160.9 EPR78518.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Calx-beta domain Kdo PF06293.9 EPR78519.1 - 1e-07 31.2 0.3 1.6e-07 30.6 0.2 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EPR78519.1 - 8.2e-07 28.4 7.5 3.1e-06 26.5 5.2 1.8 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EPR78519.1 - 1e-05 24.9 3.3 1.2e-05 24.7 1.2 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 EPR78519.1 - 0.00038 19.6 2.2 0.00099 18.2 1.6 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPR78519.1 - 0.01 15.6 0.0 9.2 5.9 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ubie_methyltran PF01209.13 EPR78519.1 - 0.039 13.0 1.9 0.11 11.6 0.8 1.8 1 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MH1 PF03165.11 EPR78521.1 - 0.06 13.3 0.2 0.35 10.8 0.1 2.0 1 1 0 1 1 1 0 MH1 domain DUF4320 PF14208.1 EPR78521.1 - 0.26 11.2 2.8 0.31 11.0 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4320) UN_NPL4 PF11543.3 EPR78521.1 - 0.27 11.5 1.9 4.1 7.7 0.3 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 CUE PF02845.11 EPR78522.1 - 1.9e-05 24.0 0.5 3.6e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 CUE domain Smr PF01713.16 EPR78522.1 - 0.002 18.3 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EPR78522.1 - 0.0033 17.3 0.4 0.0085 16.0 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1771) MRG PF05712.8 EPR78523.1 - 2.1e-06 26.7 2.2 4.7e-06 25.6 1.5 1.6 1 1 0 1 1 1 1 MRG DUF2097 PF09870.4 EPR78523.1 - 0.00064 19.7 3.2 0.7 10.0 0.6 2.9 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2097) TraY PF05509.6 EPR78524.1 - 0.042 13.6 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 TraY domain Viral_cys_rich PF08008.7 EPR78524.1 - 1.1 8.8 4.1 2.6 7.6 2.9 1.6 1 0 0 1 1 1 0 Viral cysteine rich Fib_alpha PF08702.5 EPR78524.1 - 1.6 8.8 4.4 2.1 8.4 3.0 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cnd1 PF12717.2 EPR78524.1 - 3.7 7.3 9.0 7.9 6.2 6.2 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 DUF365 PF04033.7 EPR78525.1 - 0.078 12.9 0.5 0.61 10.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF365) RNA_pol_Rpc34 PF05158.7 EPR78526.1 - 1.5e-27 96.6 14.7 2.1e-26 92.8 10.2 2.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.12 EPR78526.1 - 0.0068 15.8 0.7 0.0068 15.8 0.5 2.2 2 2 1 3 3 3 1 TFIIE alpha subunit TrmB PF01978.14 EPR78526.1 - 0.0081 15.8 2.3 2.5 7.8 0.1 2.5 1 1 1 2 2 2 2 Sugar-specific transcriptional regulator TrmB DUF433 PF04255.9 EPR78526.1 - 0.028 13.8 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF433) HTH_24 PF13412.1 EPR78526.1 - 0.052 12.9 0.4 0.052 12.9 0.3 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Sulfolobus_pRN PF05584.6 EPR78526.1 - 0.056 13.4 1.8 0.13 12.2 0.3 2.2 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein HxlR PF01638.12 EPR78526.1 - 0.073 12.7 3.4 2.7 7.6 0.3 2.5 1 1 1 2 2 2 0 HxlR-like helix-turn-helix Imm36 PF15597.1 EPR78526.1 - 0.13 12.3 1.5 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Immunity protein 36 HTH_9 PF08221.6 EPR78526.1 - 0.19 11.6 1.6 3 7.7 0.2 2.5 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Rib_5-P_isom_A PF06026.9 EPR78528.1 - 3e-32 111.2 0.5 3e-32 111.2 0.3 1.3 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.8 EPR78528.1 - 8e-05 21.6 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Putative sugar-binding domain RE_HindVP PF09519.5 EPR78528.1 - 0.001 18.0 0.3 0.0019 17.1 0.2 1.4 1 0 0 1 1 1 1 HindVP restriction endonuclease Nucleoporin_N PF08801.6 EPR78529.1 - 0.0068 15.2 1.0 0.0068 15.2 0.7 1.7 2 0 0 2 2 2 1 Nup133 N terminal like DUF4595 PF15283.1 EPR78529.1 - 0.16 11.6 13.7 0.015 15.0 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4595) with porin-like fold Mucin PF01456.12 EPR78530.1 - 2.1 8.0 6.1 2.8 7.7 4.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-AD PF07776.10 EPR78531.1 - 0.1 12.5 2.3 4.9 7.2 0.0 2.6 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Golgin_A5 PF09787.4 EPR78532.1 - 0.63 8.4 3.9 3.9 5.8 0.4 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF4200 PF13863.1 EPR78532.1 - 0.66 9.9 5.5 0.17 11.8 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Occludin_ELL PF07303.8 EPR78532.1 - 3.8 8.3 7.2 9.3 7.0 1.7 2.9 2 1 1 3 3 3 0 Occludin homology domain Med4 PF10018.4 EPR78532.1 - 5.8 6.2 6.7 1 8.7 0.3 2.3 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 LRR_4 PF12799.2 EPR78533.1 - 3.2e-14 52.1 20.0 7.5e-09 35.0 1.3 2.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78533.1 - 7.9e-11 41.5 11.5 1.5e-08 34.2 0.3 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR78533.1 - 6.4e-06 25.5 8.8 0.14 12.2 0.1 4.8 4 0 0 4 4 4 2 Leucine Rich Repeat Barstar PF01337.13 EPR78533.1 - 0.0084 15.9 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 Barstar (barnase inhibitor) LRR_7 PF13504.1 EPR78533.1 - 0.12 12.6 8.4 0.76 10.2 0.0 4.1 4 1 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EPR78533.1 - 1.4 9.2 8.5 8.1 6.8 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LMBR1 PF04791.11 EPR78534.1 - 0.81 8.1 7.3 1 7.8 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SGS PF05002.10 EPR78535.1 - 9.2e-19 66.9 1.9 1.7e-18 66.1 1.3 1.6 1 0 0 1 1 1 1 SGS domain CBM_15 PF03426.9 EPR78535.1 - 0.069 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Homeobox PF00046.24 EPR78537.1 - 1.7e-18 65.9 6.4 5.1e-18 64.4 0.6 2.6 2 0 0 2 2 2 2 Homeobox domain Condensation PF00668.15 EPR78537.1 - 0.064 12.0 0.1 0.16 10.8 0.1 1.5 2 0 0 2 2 2 0 Condensation domain tRNA-synt_1d PF00750.14 EPR78538.1 - 6.6e-77 258.7 12.5 1e-76 258.0 8.7 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EPR78538.1 - 5.3e-22 78.0 0.6 1.8e-21 76.2 0.4 2.0 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EPR78538.1 - 0.0016 18.9 0.5 0.0016 18.9 0.3 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain SAP PF02037.22 EPR78539.1 - 2.7e-06 26.7 0.3 5.5e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 EPR78539.1 - 0.012 15.3 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Ish1 PF10281.4 EPR78539.1 - 0.023 14.7 0.1 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein TRCF PF03461.10 EPR78539.1 - 0.42 10.5 7.6 3.8 7.5 0.8 2.7 1 1 2 3 3 3 0 TRCF domain KH_1 PF00013.24 EPR78539.1 - 1.4 8.6 5.7 4.3 7.0 3.9 2.0 1 1 0 1 1 1 0 KH domain DUF4662 PF15578.1 EPR78539.1 - 2.6 7.5 6.6 2.9 7.4 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) TipAS PF07739.8 EPR78539.1 - 5.6 7.3 9.1 1.6 9.0 3.3 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF1682 PF07946.9 EPR78539.1 - 6.5 5.4 20.3 8.9 5.0 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ricin_B_lectin PF00652.17 EPR78540.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 EPR78540.1 - 0.047 13.0 0.1 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family AATF-Che1 PF13339.1 EPR78541.1 - 0.015 15.4 1.2 0.024 14.7 0.8 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor APG6 PF04111.7 EPR78541.1 - 0.03 13.3 5.4 0.042 12.8 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NCKAP5 PF15246.1 EPR78541.1 - 0.054 12.8 0.2 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein RNase_HII PF01351.13 EPR78541.1 - 0.49 10.0 4.9 0.64 9.6 3.4 1.3 1 0 0 1 1 1 0 Ribonuclease HII HIT PF01230.18 EPR78542.1 - 7.1e-20 71.3 0.2 9.7e-20 70.9 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPR78542.1 - 5.3e-09 36.3 0.1 8e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.12 EPR78542.1 - 0.00034 20.1 0.1 0.00066 19.2 0.1 1.4 1 1 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF1474 PF07342.6 EPR78542.1 - 0.013 15.7 1.1 0.033 14.4 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) Rod_C PF10493.4 EPR78542.1 - 0.065 11.5 0.0 0.073 11.3 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region HIT PF01230.18 EPR78543.1 - 1e-19 70.8 2.2 1.7e-19 70.1 1.6 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPR78543.1 - 5.1e-07 29.9 3.5 5.1e-07 29.9 2.5 1.6 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPR78543.1 - 0.0066 16.0 1.3 0.0091 15.6 0.9 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 TFIIE_alpha PF02002.12 EPR78544.1 - 3.5e-06 26.4 1.1 3.5e-06 26.4 0.8 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit HTH_24 PF13412.1 EPR78544.1 - 0.00032 20.0 2.0 0.00033 19.9 0.4 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sulfolobus_pRN PF05584.6 EPR78544.1 - 0.0028 17.5 1.1 0.0055 16.6 0.1 1.9 2 0 0 2 2 2 1 Sulfolobus plasmid regulatory protein HTH_43 PF09904.4 EPR78544.1 - 0.0037 17.0 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix TrmB PF01978.14 EPR78544.1 - 0.0046 16.6 0.3 0.011 15.4 0.1 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.7 EPR78544.1 - 0.0052 16.3 0.4 0.042 13.4 0.0 2.6 2 1 0 2 2 2 1 HTH domain LOH1CR12 PF10158.4 EPR78544.1 - 0.0062 16.3 1.4 0.0062 16.3 1.0 2.1 2 0 0 2 2 2 1 Tumour suppressor protein Rrf2 PF02082.15 EPR78544.1 - 0.043 13.9 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DUF2582 PF10771.4 EPR78544.1 - 0.086 12.7 0.5 0.31 10.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2582) RNA_pol_Rpb5_N PF03871.9 EPR78544.1 - 0.09 13.2 2.4 0.16 12.4 0.3 2.2 1 1 1 2 2 2 0 RNA polymerase Rpb5, N-terminal domain IncA PF04156.9 EPR78544.1 - 0.13 11.8 4.1 0.048 13.2 0.4 2.0 1 1 1 2 2 2 0 IncA protein UBN2 PF14223.1 EPR78544.1 - 0.15 11.8 9.9 1 9.1 0.5 3.1 2 2 1 3 3 3 0 gag-polypeptide of LTR copia-type CheD PF03975.8 EPR78544.1 - 0.16 11.7 1.1 0.46 10.2 0.2 2.0 2 0 0 2 2 2 0 CheD chemotactic sensory transduction TagA PF12561.3 EPR78544.1 - 0.16 11.9 1.7 0.28 11.1 1.0 1.6 1 1 0 1 1 1 0 ToxR activated gene A lipoprotein HALZ PF02183.13 EPR78544.1 - 3 7.6 9.4 0.19 11.4 1.5 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Nup54 PF13874.1 EPR78545.1 - 2.6e-07 30.4 0.4 6e-07 29.2 0.3 1.8 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 FliD_C PF07195.7 EPR78545.1 - 0.0019 17.5 0.3 0.0019 17.5 0.2 2.5 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus EST1 PF10374.4 EPR78545.1 - 0.051 13.5 6.0 0.38 10.7 0.8 2.2 1 1 1 2 2 2 0 Telomerase activating protein Est1 DUF1342 PF07072.6 EPR78545.1 - 0.082 12.5 6.1 0.068 12.8 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) HALZ PF02183.13 EPR78545.1 - 0.4 10.4 5.0 0.7 9.6 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Vip3A_N PF12495.3 EPR78545.1 - 0.6 9.7 8.5 0.066 12.8 1.8 2.0 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal Picorna_P3A PF06363.6 EPR78547.1 - 0.001 19.0 1.2 0.001 19.0 0.8 1.9 2 0 0 2 2 2 1 Picornaviridae P3A protein LRR19-TM PF15176.1 EPR78547.1 - 0.28 10.8 5.7 1.4 8.6 0.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF3329 PF11808.3 EPR78547.1 - 0.68 10.0 9.3 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF3353 PF11833.3 EPR78547.1 - 0.78 9.1 4.8 4.6 6.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) YlaH PF14036.1 EPR78547.1 - 0.96 9.5 15.1 0.51 10.4 0.6 3.2 2 1 1 3 3 3 0 YlaH-like protein Sad1_UNC PF07738.8 EPR78548.1 - 3.9e-10 39.6 0.8 5e-10 39.2 0.6 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NIF PF03031.13 EPR78551.1 - 3.5e-17 62.5 1.4 4.3e-17 62.2 1.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EPR78551.1 - 0.0055 16.9 0.0 0.019 15.2 0.0 1.6 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPR78551.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPR78551.1 - 0.061 13.7 0.0 0.2 12.0 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EPR78551.1 - 0.088 12.2 0.2 0.63 9.4 0.0 2.2 1 1 1 2 2 2 0 Polynucleotide kinase 3 phosphatase Arg_repressor_C PF02863.13 EPR78551.1 - 0.09 12.2 0.0 0.86 9.1 0.0 2.3 2 1 0 2 2 2 0 Arginine repressor, C-terminal domain Sad1_UNC PF07738.8 EPR78553.1 - 0.05 13.3 0.3 0.076 12.8 0.2 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal DUF4506 PF14958.1 EPR78553.1 - 0.079 12.5 2.7 0.15 11.6 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4506) UDPGP PF01704.13 EPR78554.1 - 4.3e-05 22.2 0.2 5e-05 21.9 0.1 1.3 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EPR78554.1 - 0.0099 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain WWE PF02825.15 EPR78555.1 - 0.034 13.5 0.6 0.16 11.4 0.1 2.3 2 0 0 2 2 2 0 WWE domain MutS_V PF00488.16 EPR78556.1 - 1.1e-72 244.2 0.2 1.9e-72 243.4 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPR78556.1 - 4.3e-20 72.3 0.0 7.3e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III AAA_22 PF13401.1 EPR78556.1 - 0.0039 17.3 0.0 0.044 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPR78556.1 - 0.064 13.1 0.0 0.064 13.1 0.0 4.9 5 1 0 5 5 5 0 AAA domain DUF2145 PF09916.4 EPR78557.1 - 0.057 12.9 0.4 0.09 12.2 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) CTNNB1_binding PF08347.6 EPR78557.1 - 0.13 12.5 0.4 0.14 12.4 0.2 1.0 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Synaptobrevin PF00957.16 EPR78558.1 - 6.2e-08 32.1 4.4 8.6e-08 31.6 0.4 2.3 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EPR78558.1 - 0.0051 16.3 1.7 0.01 15.3 1.2 1.6 1 1 0 1 1 1 1 Regulated-SNARE-like domain GATA PF00320.22 EPR78560.1 - 0.00031 20.0 3.1 0.00059 19.1 2.2 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-CHY PF05495.7 EPR78561.1 - 4.2e-12 46.0 19.9 2.6e-11 43.5 11.6 2.8 2 1 0 2 2 2 1 CHY zinc finger zf-RVT PF13966.1 EPR78562.1 - 8.4 6.7 9.3 3.6 7.9 0.1 3.2 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase Prenyltrans PF00432.16 EPR78566.1 - 1.9e-50 168.0 4.2 9.9e-13 47.4 0.0 5.8 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPR78566.1 - 7.4e-26 90.7 0.0 2.9e-14 53.4 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPR78566.1 - 7.9e-09 35.5 0.0 0.0033 17.4 0.0 3.7 3 1 0 3 3 3 3 Prenyltransferase-like EGF_CA PF07645.10 EPR78566.1 - 0.31 11.0 4.6 33 4.5 0.0 3.7 3 0 0 3 3 3 0 Calcium-binding EGF domain EF-hand_7 PF13499.1 EPR78567.1 - 5.7e-10 39.1 7.4 9.1e-06 25.7 0.9 2.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EPR78567.1 - 1.2e-05 24.7 0.5 4.6e-05 22.9 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EPR78567.1 - 1.9e-05 23.6 1.7 5.1e-05 22.2 0.1 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EPR78567.1 - 0.00028 20.4 1.5 0.0037 16.8 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPR78567.1 - 0.00072 18.7 0.1 0.0024 17.1 0.1 1.9 1 0 0 1 1 1 1 EF hand mRNA_triPase PF02940.10 EPR78568.1 - 6.3e-31 107.7 12.1 9e-30 104.0 8.4 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain YscJ_FliF PF01514.12 EPR78568.1 - 0.017 14.2 0.2 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family CUB_2 PF02408.15 EPR78568.1 - 0.041 13.4 0.6 0.15 11.6 0.3 2.0 1 1 0 1 1 1 0 CUB-like domain DUF788 PF05620.6 EPR78570.1 - 1e-16 61.2 6.1 1.2e-16 61.0 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) E2F_TDP PF02319.15 EPR78571.1 - 3.6e-16 58.4 0.2 9e-16 57.2 0.0 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EPR78571.1 - 0.0016 18.1 0.0 0.0046 16.6 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 EPR78571.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 B-block binding subunit of TFIIIC SH3BP5 PF05276.9 EPR78571.1 - 0.0078 15.5 0.7 0.014 14.7 0.5 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) HTH_17 PF12728.2 EPR78571.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Vpu PF00558.14 EPR78574.1 - 3.1 7.4 5.0 1.9 8.1 0.1 2.6 3 0 0 3 3 3 0 Vpu protein EcsB PF05975.7 EPR78575.1 - 2 6.7 23.0 0.53 8.6 0.6 2.2 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Strabismus PF06638.6 EPR78575.1 - 3.5 5.8 9.1 4.5 5.4 6.3 1.1 1 0 0 1 1 1 0 Strabismus protein DUF3270 PF11674.3 EPR78575.1 - 7.8 6.5 21.7 0.78 9.7 2.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) Zip PF02535.17 EPR78576.1 - 3.2e-35 121.6 23.7 1.4e-25 90.0 4.7 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter RrnaAD PF00398.15 EPR78579.1 - 6.1e-62 209.0 1.2 7e-62 208.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EPR78579.1 - 2.7e-07 30.6 0.0 3.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR78579.1 - 3.5e-07 30.7 0.0 5.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPR78579.1 - 2.9e-06 26.9 0.2 5e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPR78579.1 - 1.3e-05 24.6 0.0 3.2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EPR78579.1 - 0.0011 19.4 0.0 0.0042 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EPR78579.1 - 0.0028 17.2 0.0 0.029 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EPR78579.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EPR78579.1 - 0.018 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EPR78579.1 - 0.04 13.5 0.2 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 EPR78579.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAH PF02671.16 EPR78579.1 - 0.065 12.8 4.0 1.8 8.2 0.3 2.9 3 0 0 3 3 3 0 Paired amphipathic helix repeat CMAS PF02353.15 EPR78579.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EPR78579.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DAOA PF15199.1 EPR78579.1 - 0.12 13.0 0.1 0.28 11.8 0.1 1.5 1 0 0 1 1 1 0 D-amino acid oxidase activator HAD_2 PF13419.1 EPR78580.1 - 8.8e-21 74.9 0.1 1.1e-20 74.6 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPR78580.1 - 1.7e-06 27.7 1.1 0.0057 16.2 0.2 2.2 2 0 0 2 2 2 2 Acid Phosphatase HAD PF12710.2 EPR78580.1 - 0.0042 17.2 0.2 0.0052 16.9 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EPR78580.1 - 0.0055 15.7 1.0 0.9 8.4 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF705) DDE_Tnp_IS1 PF03400.8 EPR78580.1 - 0.0061 16.6 0.1 0.021 14.9 0.0 1.9 2 1 0 2 2 2 1 IS1 transposase DUF3195 PF11424.3 EPR78580.1 - 0.059 13.5 0.9 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3195) Queuosine_synth PF02547.10 EPR78581.1 - 0.0017 17.1 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein GAT PF03127.9 EPR78582.1 - 0.017 15.0 2.8 4.4 7.3 0.0 3.9 4 0 0 4 4 4 0 GAT domain TIP49 PF06068.8 EPR78584.1 - 5.2e-22 78.1 14.2 2.5e-21 75.8 9.9 2.2 1 1 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EPR78584.1 - 0.00059 19.9 2.4 0.19 11.8 0.5 2.8 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPR78584.1 - 0.0014 18.3 3.7 0.0014 18.3 2.6 2.2 2 1 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EPR78584.1 - 0.003 17.7 2.0 0.003 17.7 1.4 3.3 3 1 0 3 3 3 1 RNA helicase DUF258 PF03193.11 EPR78584.1 - 0.017 14.3 0.5 0.043 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MoaC PF01967.16 EPR78584.1 - 0.017 14.7 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 MoaC family NAC PF01849.13 EPR78584.1 - 0.035 13.6 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 NAC domain Miro PF08477.8 EPR78584.1 - 0.055 13.9 0.6 0.31 11.5 0.0 2.4 2 1 0 2 2 2 0 Miro-like protein eRF1_3 PF03465.10 EPR78584.1 - 0.14 12.4 1.3 0.29 11.4 0.2 2.1 2 0 0 2 2 2 0 eRF1 domain 3 Motile_Sperm PF00635.21 EPR78585.1 - 2.8e-14 52.6 0.2 4.3e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF2216 PF10226.4 EPR78588.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) EFG_IV PF03764.13 EPR78588.1 - 0.13 11.7 0.3 7.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G, domain IV ASFV_p27 PF06556.6 EPR78589.1 - 0.0081 16.0 4.4 0.0081 16.0 3.0 2.8 2 2 1 3 3 3 1 IAP-like protein p27 C-terminus zf-RING-like PF08746.6 EPR78589.1 - 0.012 15.5 4.1 0.012 15.5 2.9 2.8 3 1 0 3 3 3 0 RING-like domain zf-RING_2 PF13639.1 EPR78589.1 - 0.016 15.0 6.1 0.016 15.0 4.2 2.3 3 0 0 3 3 3 0 Ring finger domain WD40 PF00400.27 EPR78590.1 - 2.3e-12 46.2 0.5 0.00018 21.2 0.1 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CDtoxinA PF03498.9 EPR78592.1 - 0.0012 18.2 1.3 0.0016 17.8 0.9 1.2 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 EPR78592.1 - 0.0097 16.2 0.5 0.014 15.7 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like CDC45 PF02724.9 EPR78593.1 - 0.092 10.7 10.5 0.099 10.6 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2870 PF11069.3 EPR78593.1 - 0.48 10.4 4.9 0.17 11.9 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2457 PF10446.4 EPR78593.1 - 9.5 4.8 17.8 14 4.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BRCA-2_OB1 PF09103.5 EPR78596.1 - 4.2e-18 65.1 0.2 4.2e-18 65.1 0.2 2.5 3 0 0 3 3 3 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 EPR78596.1 - 1.7e-05 23.9 0.3 5.1e-05 22.4 0.2 1.8 1 0 0 1 1 1 1 BRCA2 repeat DUF2435 PF10363.4 EPR78596.1 - 0.0096 15.8 0.1 0.079 12.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) MBD_C PF14048.1 EPR78596.1 - 0.075 13.6 0.1 12 6.5 0.0 3.6 3 0 0 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 PSD4 PF07631.6 EPR78596.1 - 0.46 10.8 4.5 6.1 7.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) zf-RING_5 PF14634.1 EPR78597.1 - 4.5e-06 26.2 11.8 7.6e-06 25.5 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPR78597.1 - 0.00075 19.1 8.2 0.0014 18.2 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR78597.1 - 0.0012 18.8 10.6 0.0024 17.8 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPR78597.1 - 0.026 14.2 5.0 0.11 12.2 3.5 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EPR78597.1 - 0.038 13.4 7.8 0.076 12.4 5.4 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_2 PF13639.1 EPR78597.1 - 0.075 12.8 9.2 0.15 11.9 6.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EPR78597.1 - 0.18 11.4 10.7 0.43 10.2 7.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPR78597.1 - 6.7 6.3 9.7 63 3.2 6.7 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Med28 PF11594.3 EPR78598.1 - 3.9 7.7 8.6 16 5.8 3.2 3.2 2 1 0 2 2 2 0 Mediator complex subunit 28 Spt20 PF12090.3 EPR78599.1 - 0.06 12.7 1.4 0.065 12.5 1.0 1.2 1 0 0 1 1 1 0 Spt20 family Ly49 PF08391.5 EPR78601.1 - 0.012 15.7 4.5 0.12 12.5 0.9 2.3 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF1312 PF07009.6 EPR78601.1 - 0.047 13.5 0.7 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) Conotoxin PF02950.12 EPR78601.1 - 0.13 13.0 1.8 0.19 12.5 0.0 2.2 3 0 0 3 3 3 0 Conotoxin DEAD PF00270.24 EPR78603.1 - 1.7e-38 131.7 0.1 3.3e-38 130.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR78603.1 - 1.6e-22 79.1 0.1 1e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR78603.1 - 1.1e-09 38.3 0.4 1.1e-09 38.3 0.3 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EPR78603.1 - 2.8e-08 33.3 2.4 5.2e-08 32.5 0.1 2.1 2 0 0 2 2 2 1 SecA DEAD-like domain SNF2_N PF00176.18 EPR78603.1 - 4.2e-05 22.4 0.2 4.2e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EPR78603.1 - 0.0028 17.6 0.3 0.017 15.0 0.1 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain PhoH PF02562.11 EPR78603.1 - 0.018 14.2 0.1 0.051 12.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 EPR78603.1 - 0.033 14.3 0.9 0.65 10.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPR78603.1 - 0.079 12.7 0.0 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EPR78603.1 - 0.12 11.2 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TLE_N PF03920.10 EPR78604.1 - 0.028 14.2 0.1 0.069 12.9 0.1 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DS PF01916.12 EPR78605.1 - 3.3e-44 151.2 6.9 4.6e-44 150.7 4.8 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EPR78605.1 - 0.017 14.2 0.5 0.024 13.7 0.3 1.3 1 1 0 1 1 1 0 Carbamoyltransferase Acetyltransf_7 PF13508.1 EPR78607.1 - 9.3e-05 22.5 0.0 0.00023 21.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPR78607.1 - 0.00056 19.8 0.0 0.00089 19.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPR78607.1 - 0.00081 19.3 0.3 0.00081 19.3 0.2 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPR78607.1 - 0.001 18.9 0.0 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase DNA_RNApol_7kD PF03604.8 EPR78607.1 - 1 8.8 8.5 0.4 10.1 0.4 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Fcf1 PF04900.7 EPR78608.1 - 4.7e-31 106.8 1.1 5.8e-31 106.5 0.3 1.5 2 0 0 2 2 2 1 Fcf1 HTH_9 PF08221.6 EPR78609.1 - 1.1e-05 25.2 0.1 2.3e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 helix-turn-helix domain DUF1801 PF08818.6 EPR78609.1 - 0.1 12.6 1.7 0.29 11.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DU1801) PhaP_Bmeg PF09602.5 EPR78610.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PilI PF10623.4 EPR78610.1 - 0.097 12.6 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI ResIII PF04851.10 EPR78610.1 - 0.31 10.8 3.4 0.38 10.5 2.4 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ChlamPMP_M PF07548.6 EPR78610.1 - 0.4 10.3 2.6 0.52 10.0 1.8 1.3 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain HECT PF00632.20 EPR78611.1 - 2.2e-28 99.3 7.1 1.7e-20 73.4 1.2 2.3 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPR78611.1 - 0.00074 19.3 0.9 0.00074 19.3 0.6 2.3 2 0 0 2 2 2 1 WW domain WD40 PF00400.27 EPR78612.1 - 1.8e-47 157.5 3.5 3.5e-12 45.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat SseC PF04888.7 EPR78613.1 - 6.3 6.0 7.2 18 4.5 0.0 3.0 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family DUF2924 PF11149.3 EPR78614.1 - 0.082 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) SEP PF08059.8 EPR78614.1 - 0.18 12.0 2.2 1.5 9.2 0.1 2.9 2 1 0 2 2 2 0 SEP domain AAA_11 PF13086.1 EPR78615.1 - 4.9e-33 114.6 2.6 7.5e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EPR78615.1 - 1.1e-09 38.2 0.0 2.1e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPR78615.1 - 2e-09 37.0 0.0 3.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EPR78615.1 - 4.1e-08 33.2 4.3 4.1e-08 33.2 3.0 2.6 1 1 1 3 3 3 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EPR78615.1 - 5.7e-07 29.2 0.2 3.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EPR78615.1 - 1.8e-06 27.5 0.7 1.8e-06 27.5 0.5 2.3 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EPR78615.1 - 6.7e-06 25.7 1.5 0.0012 18.3 0.3 3.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 EPR78615.1 - 3e-05 23.7 1.8 0.00036 20.2 0.3 2.5 2 1 0 2 2 2 1 Helicase UvrD-helicase PF00580.16 EPR78615.1 - 4.1e-05 23.0 11.8 0.0033 16.7 0.0 3.2 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EPR78615.1 - 0.0011 17.9 3.3 0.016 14.2 2.3 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EPR78615.1 - 0.0016 18.1 0.0 0.0043 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EPR78615.1 - 0.0028 16.9 0.0 0.0063 15.7 0.0 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 EPR78615.1 - 0.0034 17.5 0.4 0.057 13.5 0.3 2.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EPR78615.1 - 0.011 15.1 0.1 0.026 13.9 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 EPR78615.1 - 0.023 14.3 13.4 0.0094 15.6 5.5 2.6 2 1 0 2 2 2 0 Archaeal ATPase Zot PF05707.7 EPR78615.1 - 0.032 13.6 1.7 0.1 12.0 0.0 2.5 3 1 1 4 4 4 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 EPR78615.1 - 0.16 12.2 3.0 0.26 11.5 1.2 2.1 2 1 0 2 2 2 0 ABC transporter AAA PF00004.24 EPR78615.1 - 8.6 6.5 11.4 3.8 7.7 2.9 3.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 EPR78616.1 - 6.2e-25 86.9 1.5 6.2e-25 86.9 1.1 2.4 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 EPR78616.1 - 0.00047 20.2 2.0 0.015 15.4 1.4 2.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPR78616.1 - 0.054 13.5 0.2 6.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Choline_transpo PF04515.7 EPR78617.1 - 1.1e-07 30.9 3.3 1.5e-07 30.4 2.3 1.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter Kinocilin PF15033.1 EPR78617.1 - 0.15 11.5 0.3 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Kinocilin protein TM_helix PF05552.7 EPR78617.1 - 7.2 6.3 12.4 0.14 11.8 2.5 2.1 2 0 0 2 2 2 0 Conserved TM helix PI3_PI4_kinase PF00454.22 EPR78618.1 - 1.2e-27 96.8 2.9 1.7e-26 93.1 0.1 3.7 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase LRR_8 PF13855.1 EPR78619.1 - 1.8e-06 27.5 0.1 4.3e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 EPR78619.1 - 2.6e-06 26.8 0.6 2.6e-06 26.8 0.4 2.4 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78619.1 - 0.00013 21.5 4.6 0.022 14.7 0.0 3.4 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EPR78619.1 - 0.014 15.3 1.0 0.12 12.5 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 EPR78619.1 - 0.014 15.4 0.1 0.15 12.3 0.0 2.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EPR78620.1 - 2.7e-14 52.3 27.8 6.4e-07 28.8 2.0 4.9 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78620.1 - 4.8e-13 48.6 22.3 8.7e-07 28.6 2.6 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EPR78620.1 - 4.4e-11 41.2 27.8 0.11 12.6 0.1 7.5 5 1 2 7 7 7 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR78620.1 - 6.7e-08 31.4 12.3 4.7 7.8 0.2 7.1 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EPR78620.1 - 3.5e-05 23.4 21.3 1.9 8.8 0.1 6.8 7 0 0 7 7 7 3 Leucine Rich repeat GNAT_acetyltran PF12746.2 EPR78620.1 - 0.091 11.5 0.1 0.17 10.6 0.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Flavodoxin_1 PF00258.20 EPR78621.1 - 2.5e-25 89.1 0.0 5.7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Radical_SAM PF04055.16 EPR78621.1 - 3.4e-21 76.1 0.1 1e-20 74.5 0.1 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EPR78621.1 - 1.4e-20 73.1 0.0 5.1e-20 71.3 0.0 2.1 1 0 0 1 1 1 1 Wyosine base formation RasGEF_N_2 PF14663.1 EPR78621.1 - 0.13 12.2 1.0 0.36 10.7 0.7 1.7 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PMM PF03332.8 EPR78622.1 - 4.9e-94 314.0 4.2 5.7e-94 313.7 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EPR78622.1 - 2.4e-07 30.6 0.4 4.9e-07 29.5 0.3 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.7 EPR78622.1 - 0.026 14.5 0.6 0.1 12.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF600 HAD PF12710.2 EPR78622.1 - 0.031 14.4 0.0 0.062 13.4 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPR78622.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-ribbon_3 PF13248.1 EPR78623.1 - 0.0018 17.3 6.2 0.0018 17.3 4.3 2.9 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 EPR78623.1 - 0.027 14.3 17.0 0.052 13.3 8.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 EPR78623.1 - 0.18 11.5 6.7 0.66 9.7 0.3 3.4 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 EPR78623.1 - 3.4 7.2 17.4 0.82 9.2 5.2 3.4 2 1 1 3 3 3 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 EPR78624.1 - 0.0025 17.3 1.6 2.2 7.9 0.0 3.1 3 0 0 3 3 3 2 Zinc finger found in FPG and IleRS RecR PF02132.10 EPR78624.1 - 0.17 11.3 0.1 0.17 11.3 0.1 3.8 3 1 1 4 4 4 0 RecR protein DZR PF12773.2 EPR78624.1 - 0.63 9.9 19.6 0.42 10.4 8.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon Sec3_C PF09763.4 EPR78625.1 - 2.3e-07 29.3 22.4 2.3e-07 29.3 15.5 2.7 2 2 0 2 2 2 1 Exocyst complex component Sec3 DUF2397 PF09660.5 EPR78626.1 - 0.088 11.3 0.5 0.12 10.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF3860 PF12976.2 EPR78626.1 - 0.09 12.5 0.8 0.14 11.9 0.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) tRNA_anti-like PF12869.2 EPR78626.1 - 0.19 11.1 3.1 0.28 10.6 2.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like WD40 PF00400.27 EPR78627.1 - 0.00026 20.7 6.3 0.008 16.0 0.0 4.7 5 1 0 5 5 5 1 WD domain, G-beta repeat RdRP PF05183.7 EPR78629.1 - 8.5e-56 189.8 1.0 2e-55 188.6 0.4 1.6 1 1 1 2 2 2 1 RNA dependent RNA polymerase PLC-beta_C PF08703.5 EPR78631.1 - 0.0026 17.5 3.5 0.0031 17.2 2.4 1.2 1 0 0 1 1 1 1 PLC-beta C terminal DUF2481 PF10654.4 EPR78631.1 - 0.053 13.2 0.5 0.059 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Methyltransf_4 PF02390.12 EPR78633.1 - 2.5e-38 131.1 0.2 3e-38 130.8 0.1 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EPR78633.1 - 0.00034 20.2 0.3 0.00063 19.3 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPR78633.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EPR78633.1 - 0.0069 16.9 0.0 0.012 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain IMS PF00817.15 EPR78633.1 - 0.0086 15.8 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family Methyltransf_23 PF13489.1 EPR78633.1 - 0.016 14.9 0.0 0.046 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EPR78633.1 - 0.023 15.1 0.0 0.055 13.9 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain DUF1805 PF08827.6 EPR78633.1 - 0.046 13.5 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) DUF3134 PF11332.3 EPR78633.1 - 0.052 13.6 1.0 0.09 12.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) CMAS PF02353.15 EPR78633.1 - 0.065 12.3 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EPR78633.1 - 0.075 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPR78633.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF819 PF05684.7 EPR78634.1 - 0.15 10.8 0.0 0.15 10.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF819) DNA_topoisoIV PF00521.15 EPR78635.1 - 0.0069 15.2 2.2 0.0084 14.9 1.5 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A COMP PF11598.3 EPR78635.1 - 0.037 14.1 0.2 0.13 12.3 0.1 1.9 1 1 0 1 1 1 0 Cartilage oligomeric matrix protein DUF2087 PF09860.4 EPR78635.1 - 0.11 12.2 0.1 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF1002 PF06207.6 EPR78635.1 - 0.77 9.0 4.6 0.89 8.8 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Brix PF04427.13 EPR78637.1 - 4.3e-19 68.9 3.3 5e-19 68.7 2.3 1.0 1 0 0 1 1 1 1 Brix domain DUF2179 PF10035.4 EPR78637.1 - 0.11 12.1 0.6 2.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) SNARE PF05739.14 EPR78639.1 - 0.00016 21.3 2.3 0.00021 20.9 1.6 1.2 1 0 0 1 1 1 1 SNARE domain NUDE_C PF04880.8 EPR78639.1 - 0.00032 21.1 1.5 0.00035 20.9 1.0 1.0 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Troponin PF00992.15 EPR78639.1 - 0.038 14.0 4.0 0.044 13.8 2.8 1.1 1 0 0 1 1 1 0 Troponin TPR_MLP1_2 PF07926.7 EPR78639.1 - 0.049 13.3 2.3 0.052 13.2 1.6 1.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phasin PF05597.6 EPR78639.1 - 0.1 12.3 1.3 0.13 11.9 0.9 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoL PF05461.6 EPR78639.1 - 0.1 11.8 1.6 0.11 11.7 1.1 1.0 1 0 0 1 1 1 0 Apolipoprotein L BLOC1_2 PF10046.4 EPR78639.1 - 0.52 10.4 5.0 0.62 10.2 3.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2570 PF10828.3 EPR78639.1 - 4.6 6.8 9.7 1.8 8.1 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Ribosomal_L2_C PF03947.13 EPR78640.1 - 2.8e-36 124.2 0.1 5.6e-36 123.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPR78640.1 - 8.5e-06 25.6 0.1 1.8e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Sod_Fe_C PF02777.13 EPR78641.1 - 0.1 12.4 1.5 0.19 11.6 1.0 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Histone PF00125.19 EPR78643.1 - 1.9e-05 24.6 0.3 2.7e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPR78643.1 - 0.00014 21.8 1.2 0.00026 20.9 0.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_S7 PF00177.16 EPR78643.1 - 0.004 16.7 3.4 0.0057 16.2 2.4 1.3 1 1 0 1 1 1 1 Ribosomal protein S7p/S5e AAA_5 PF07728.9 EPR78644.1 - 6e-61 204.2 1.4 6.4e-16 58.3 0.0 6.2 5 1 0 5 5 5 5 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPR78644.1 - 3e-13 50.0 9.9 0.00052 20.1 0.0 5.2 4 2 2 6 6 5 3 AAA domain AAA_3 PF07726.6 EPR78644.1 - 1.1e-12 47.6 0.0 0.00022 20.8 0.0 6.1 5 2 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EPR78644.1 - 3.6e-12 46.6 3.3 0.0023 18.1 0.0 5.3 3 2 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPR78644.1 - 3.4e-11 42.8 1.1 0.00089 18.7 0.0 5.3 6 1 1 7 7 6 2 Sigma-54 interaction domain T2SE PF00437.15 EPR78644.1 - 1e-08 34.4 2.9 0.036 12.9 0.0 3.3 3 0 0 3 3 3 3 Type II/IV secretion system protein AAA_16 PF13191.1 EPR78644.1 - 4.2e-08 33.4 0.0 0.036 14.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain Miro PF08477.8 EPR78644.1 - 1.6e-07 31.8 0.0 0.056 13.9 0.0 4.5 4 0 0 4 4 4 2 Miro-like protein ABC_tran PF00005.22 EPR78644.1 - 6.4e-07 29.7 16.1 0.00044 20.5 0.1 4.5 4 1 0 4 4 3 2 ABC transporter MobB PF03205.9 EPR78644.1 - 7.2e-07 28.9 0.4 0.073 12.7 0.0 3.5 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EPR78644.1 - 1.1e-06 28.3 0.0 0.11 12.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain PduV-EutP PF10662.4 EPR78644.1 - 6.3e-06 25.7 0.2 0.024 14.1 0.0 3.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EPR78644.1 - 7.7e-06 25.3 0.1 0.0066 15.9 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EPR78644.1 - 2.3e-05 23.6 0.0 0.71 8.9 0.0 5.0 6 1 1 7 7 6 1 Magnesium chelatase, subunit ChlI AAA_6 PF12774.2 EPR78644.1 - 5.6e-05 22.7 0.2 0.35 10.3 0.0 3.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 Sigma54_activ_2 PF14532.1 EPR78644.1 - 7.1e-05 22.8 0.1 0.99 9.4 0.0 4.8 5 0 0 5 5 5 1 Sigma-54 interaction domain NACHT PF05729.7 EPR78644.1 - 9.2e-05 22.1 0.0 0.03 13.9 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EPR78644.1 - 0.00011 21.3 0.0 5.9 5.9 0.0 4.0 4 0 0 4 4 3 0 Zeta toxin MCM PF00493.18 EPR78644.1 - 0.00013 20.8 3.9 0.41 9.3 0.0 4.6 4 0 0 4 4 4 1 MCM2/3/5 family AAA_17 PF13207.1 EPR78644.1 - 0.00028 21.6 21.6 0.036 14.8 0.2 5.2 5 1 1 6 6 4 2 AAA domain AAA_28 PF13521.1 EPR78644.1 - 0.00035 20.5 0.0 1.5 8.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPR78644.1 - 0.00039 19.6 0.5 0.45 9.6 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPR78644.1 - 0.00045 20.1 0.0 0.51 10.2 0.0 4.4 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPR78644.1 - 0.00046 19.8 0.0 0.79 9.5 0.0 3.3 3 0 0 3 3 3 1 Part of AAA domain UPF0079 PF02367.12 EPR78644.1 - 0.00067 19.2 0.0 0.95 9.0 0.0 3.7 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EPR78644.1 - 0.00073 19.0 0.1 1.1 8.6 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DEAD PF00270.24 EPR78644.1 - 0.00076 19.0 0.0 4.8 6.6 0.0 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_14 PF13173.1 EPR78644.1 - 0.0021 17.9 1.5 0.0021 17.9 1.0 8.3 5 4 2 7 7 6 2 AAA domain PhoH PF02562.11 EPR78644.1 - 0.0027 16.9 0.0 4.9 6.3 0.0 3.6 3 0 0 3 3 3 0 PhoH-like protein ATP-synt_ab PF00006.20 EPR78644.1 - 0.0029 17.1 0.0 1 8.8 0.0 2.8 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EPR78644.1 - 0.0092 16.2 2.5 0.0092 16.2 1.7 6.3 7 1 0 7 7 4 3 AAA domain CPT PF07931.7 EPR78644.1 - 0.013 15.1 0.0 0.28 10.7 0.0 3.2 5 0 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein TrwB_AAD_bind PF10412.4 EPR78644.1 - 0.013 14.0 0.0 10 4.6 0.0 3.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 EPR78644.1 - 0.024 14.0 0.0 10 5.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1529 PF07485.6 EPR78644.1 - 0.026 14.2 0.1 0.73 9.5 0.0 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) FtsK_SpoIIIE PF01580.13 EPR78644.1 - 0.053 12.9 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EPR78644.1 - 0.074 12.4 0.8 2.3 7.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EPR78644.1 - 0.12 12.0 3.8 3.6 7.2 0.0 3.4 4 0 0 4 4 2 0 NTPase ABC_tran PF00005.22 EPR78645.1 - 3.1e-15 56.6 0.0 1.1e-14 54.9 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPR78645.1 - 9.4e-08 32.3 6.2 0.00029 20.8 0.3 2.8 1 1 2 3 3 3 2 AAA domain AAA_15 PF13175.1 EPR78645.1 - 3.8e-07 29.4 1.6 0.016 14.2 0.4 2.2 1 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EPR78645.1 - 1.5e-05 24.3 0.5 0.0047 16.1 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPR78645.1 - 8.7e-05 22.9 5.1 0.00015 22.1 3.3 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPR78645.1 - 0.00068 19.8 0.1 0.0018 18.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EPR78645.1 - 0.001 17.6 0.1 0.0094 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPR78645.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPR78645.1 - 0.0036 17.4 0.1 0.02 15.0 0.0 2.3 2 1 0 3 3 3 1 AAA domain G-alpha PF00503.15 EPR78645.1 - 0.0068 15.1 0.0 0.01 14.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 EPR78645.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 EPR78645.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EPR78645.1 - 0.018 15.2 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EPR78645.1 - 0.036 13.7 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPR78645.1 - 0.042 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EPR78645.1 - 0.053 13.1 0.1 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EPR78645.1 - 0.059 12.5 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 EPR78645.1 - 0.061 13.0 0.7 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EPR78645.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EPR78645.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAP_central PF04928.12 EPR78646.1 - 1.3e-86 289.5 0.0 1.7e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EPR78646.1 - 3.3e-25 88.4 2.4 6.4e-25 87.5 1.7 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EPR78646.1 - 1.9e-06 28.1 1.1 4.4e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EPR78646.1 - 0.045 13.8 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm Slx4 PF09494.5 EPR78646.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease ASF1_hist_chap PF04729.8 EPR78649.1 - 5e-22 78.1 2.5 2.4e-21 75.9 0.6 2.3 2 0 0 2 2 2 1 ASF1 like histone chaperone Sec23_trunk PF04811.10 EPR78651.1 - 7.2e-33 113.9 0.1 1.1e-32 113.3 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPR78651.1 - 2.9e-17 61.9 0.9 5.7e-17 61.0 0.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPR78651.1 - 5.2e-15 55.7 0.1 1.3e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPR78651.1 - 2.6e-14 52.4 3.9 2.6e-14 52.4 2.7 2.1 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPR78651.1 - 1.7e-05 24.3 0.3 0.00015 21.3 0.2 2.3 1 1 0 1 1 1 1 Gelsolin repeat Med2 PF11214.3 EPR78651.1 - 0.041 13.9 0.4 5.2 7.1 0.0 3.0 2 0 0 2 2 2 0 Mediator complex subunit 2 zf-RanBP PF00641.13 EPR78651.1 - 0.11 11.6 0.2 0.24 10.5 0.2 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-MIZ PF02891.15 EPR78651.1 - 0.14 11.7 2.6 0.28 10.7 0.8 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ribosomal_S8e PF01201.17 EPR78652.1 - 1.2e-33 116.0 0.0 1.2e-32 112.8 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3393 PF11873.3 EPR78652.1 - 0.77 9.2 5.7 1.4 8.3 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3393) LppC PF04348.8 EPR78653.1 - 0.021 13.4 0.1 0.022 13.3 0.1 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Viral_protease PF08715.5 EPR78653.1 - 0.076 12.0 0.2 0.096 11.7 0.2 1.1 1 0 0 1 1 1 0 Papain like viral protease Rsa3 PF14615.1 EPR78653.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Imm6 PF14434.1 EPR78653.1 - 0.15 11.7 2.9 0.19 11.4 0.1 2.2 1 1 1 2 2 2 0 Immunity protein Imm6 DUF1825 PF08855.5 EPR78653.1 - 0.24 11.4 3.8 0.98 9.4 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) Rad51 PF08423.6 EPR78654.1 - 4.4e-136 451.7 0.0 6.5e-136 451.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPR78654.1 - 5.6e-12 45.4 0.0 8.7e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EPR78654.1 - 6.4e-10 39.0 0.1 1.3e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EPR78654.1 - 2.1e-09 36.8 0.0 2.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EPR78654.1 - 2.3e-07 30.2 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 EPR78654.1 - 0.00067 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3449 PF11931.3 EPR78657.1 - 2.4e-28 99.0 12.6 2.4e-28 99.0 8.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EPR78657.1 - 0.00078 19.5 11.2 0.0022 18.1 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Metalloenzyme PF01676.13 EPR78657.1 - 0.054 12.8 0.1 0.071 12.4 0.1 1.1 1 0 0 1 1 1 0 Metalloenzyme superfamily zf-C2H2_jaz PF12171.3 EPR78657.1 - 1.4 9.1 20.0 0.34 11.1 2.3 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ras PF00071.17 EPR78658.1 - 2.1e-55 186.5 0.1 2.5e-55 186.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR78658.1 - 6.8e-18 65.2 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPR78658.1 - 1.9e-13 49.9 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPR78658.1 - 6.8e-07 28.6 0.0 8.4e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPR78658.1 - 5.6e-06 25.9 0.0 8e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPR78658.1 - 0.0011 18.9 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPR78658.1 - 0.0054 16.5 0.5 0.0073 16.1 0.3 1.5 1 1 0 1 1 1 1 Dynamin family DUF4623 PF15416.1 EPR78658.1 - 0.019 13.3 0.0 0.025 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) AAA_14 PF13173.1 EPR78658.1 - 0.032 14.1 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPR78658.1 - 0.25 11.0 2.6 1.5 8.5 1.8 2.1 1 1 0 1 1 1 0 Archaeal ATPase Orbi_NS3 PF01616.11 EPR78659.1 - 0.28 10.1 4.5 0.11 11.4 0.3 2.1 2 1 0 2 2 2 0 Orbivirus NS3 zf-C4H2 PF10146.4 EPR78659.1 - 0.28 11.1 1.7 0.6 10.1 1.2 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein CH PF00307.26 EPR78660.1 - 7.9e-11 41.9 15.5 7.6e-08 32.3 0.1 3.7 4 2 0 4 4 4 2 Calponin homology (CH) domain MAT1 PF06391.8 EPR78661.1 - 5.4e-18 65.2 24.9 7.2e-17 61.6 17.2 2.2 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EPR78661.1 - 3.6e-05 23.3 10.5 0.00013 21.5 7.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR78661.1 - 0.00017 21.2 7.3 0.00037 20.1 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPR78661.1 - 0.0023 17.5 8.0 0.0055 16.3 5.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR78661.1 - 0.027 14.5 10.1 0.083 12.9 7.0 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) APG6 PF04111.7 EPR78661.1 - 0.059 12.4 11.1 0.074 12.0 7.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-ribbon_3 PF13248.1 EPR78661.1 - 0.24 10.6 4.0 4.9 6.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 EPR78661.1 - 0.29 10.7 13.0 10 5.8 9.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.9 EPR78661.1 - 0.34 10.6 2.7 4 7.1 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS POX PF07526.6 EPR78661.1 - 0.37 11.0 3.7 0.76 10.0 2.6 1.6 1 0 0 1 1 1 0 Associated with HOX zinc_ribbon_2 PF13240.1 EPR78661.1 - 0.45 10.0 5.7 4.3 6.9 0.6 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EPR78661.1 - 0.61 9.9 8.2 3.3 7.5 5.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 EPR78661.1 - 0.88 9.4 8.1 3.1 7.7 0.1 2.8 2 1 1 3 3 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ISL3 PF14690.1 EPR78661.1 - 2.2 8.3 7.2 3.5 7.7 0.0 2.9 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.2 EPR78661.1 - 2.6 7.9 7.6 2.5 7.9 1.4 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain CHD5 PF04420.9 EPR78661.1 - 2.7 7.6 5.6 4 7.0 3.3 1.8 1 1 0 1 1 1 0 CHD5-like protein zf-RING_2 PF13639.1 EPR78661.1 - 3.5 7.5 10.3 11 5.9 7.2 1.9 1 1 0 1 1 1 0 Ring finger domain Na_Ca_ex PF01699.19 EPR78663.1 - 2.1e-23 82.4 31.0 3.2e-14 52.7 5.1 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein zf-H2C2_2 PF13465.1 EPR78664.1 - 6.6e-07 29.3 14.2 8.9e-07 28.9 2.4 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPR78664.1 - 8e-07 28.9 9.3 0.0031 17.7 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPR78664.1 - 2.7e-06 27.3 12.8 0.0011 19.1 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-TRAF PF02176.13 EPR78664.1 - 0.02 15.2 1.3 0.02 15.2 0.9 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger WD40 PF00400.27 EPR78665.1 - 8.4e-29 98.3 6.7 0.00022 20.9 0.0 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat dUTPase_2 PF08761.6 EPR78667.1 - 0.3 11.1 2.4 11 6.1 0.1 2.0 1 1 1 2 2 2 0 dUTPase TEBP_beta PF07404.6 EPR78668.1 - 0.25 10.4 1.9 0.27 10.3 1.3 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) ARID PF01388.16 EPR78669.1 - 5.1e-11 42.2 0.8 1.2e-10 41.1 0.2 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Tudor-knot PF11717.3 EPR78669.1 - 0.064 12.9 0.7 0.22 11.2 0.5 2.0 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EPR78669.1 - 1.2 8.9 6.0 0.12 12.0 0.4 2.2 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Cytochrome-c551 PF10643.4 EPR78671.1 - 0.0095 15.2 2.2 0.032 13.5 0.1 2.1 1 1 0 2 2 2 1 Photosystem P840 reaction-centre cytochrome c-551 SPK PF04435.13 EPR78671.1 - 0.12 12.2 0.2 0.12 12.2 0.2 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF545) HCO3_cotransp PF00955.16 EPR78671.1 - 0.66 8.5 4.5 0.28 9.7 1.5 1.5 1 1 1 2 2 2 0 HCO3- transporter family FERM_M PF00373.13 EPR78671.1 - 0.92 9.6 3.7 0.98 9.6 0.6 2.4 2 1 0 2 2 2 0 FERM central domain RNA_pol_I_A49 PF06870.7 EPR78672.1 - 7.1e-05 21.5 1.3 9.5e-05 21.1 0.1 1.7 2 0 0 2 2 2 1 A49-like RNA polymerase I associated factor DDE_Tnp_1 PF01609.16 EPR78673.1 - 0.026 14.0 1.2 0.041 13.4 0.8 1.4 1 1 0 1 1 1 0 Transposase DDE domain DUF3110 PF11360.3 EPR78673.1 - 0.053 13.3 1.8 0.082 12.7 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3110) AP-5_subunit_s1 PF15001.1 EPR78673.1 - 0.12 12.2 0.7 0.34 10.8 0.4 1.7 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Septin PF00735.13 EPR78674.1 - 0.00037 19.6 0.0 0.00058 18.9 0.0 1.3 1 1 0 1 1 1 1 Septin Miro PF08477.8 EPR78674.1 - 0.014 15.8 0.0 0.028 14.9 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EPR78674.1 - 0.043 13.9 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EPR78674.1 - 0.068 12.5 0.1 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 Ras family Pox_TAA1 PF03295.9 EPR78674.1 - 0.11 12.1 0.5 21 4.8 0.5 2.6 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal AAA_16 PF13191.1 EPR78674.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPR78674.1 - 0.47 10.7 2.7 0.86 9.8 1.9 1.6 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EPR78674.1 - 3.1 8.0 14.1 5.5 7.2 9.4 1.8 1 1 0 1 1 1 0 AAA domain DDE_Tnp_IS1595 PF12762.2 EPR78675.1 - 5.9e-18 65.1 0.3 7e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DDE_Tnp_IS240 PF13610.1 EPR78675.1 - 0.01 15.8 0.1 0.011 15.7 0.1 1.1 1 0 0 1 1 1 0 DDE domain DDE_Tnp_IS66 PF03050.9 EPR78675.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Transposase IS66 family HTH_45 PF14947.1 EPR78676.1 - 0.0044 16.8 6.2 0.14 12.0 1.0 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix Paramyxo_NS_C PF02725.9 EPR78676.1 - 0.14 11.7 0.9 5.1 6.6 0.0 2.1 2 0 0 2 2 2 0 Non-structural protein C LRR_4 PF12799.2 EPR78678.1 - 1.1e-08 34.5 18.9 2.6e-08 33.2 4.4 8.3 5 5 4 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78678.1 - 2e-06 27.4 9.1 2e-06 27.4 6.3 7.1 6 2 1 8 8 8 3 Leucine rich repeat LRR_1 PF00560.28 EPR78678.1 - 0.45 10.7 42.8 1.2 9.4 0.4 8.8 10 0 0 10 10 10 0 Leucine Rich Repeat TetR_C_8 PF14278.1 EPR78679.1 - 0.34 11.3 3.6 0.76 10.2 2.5 1.6 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Ribosomal_L15e PF00827.12 EPR78681.1 - 1e-74 250.2 8.5 1.2e-74 250.0 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF2363 PF10155.4 EPR78682.1 - 0.12 12.3 2.7 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) zf-UBP PF02148.14 EPR78684.1 - 1.1e-14 54.2 10.2 1.1e-14 54.2 7.0 2.8 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein SDH_beta PF03315.10 EPR78685.1 - 0.4 10.7 1.5 0.88 9.6 0.5 2.0 1 1 1 2 2 2 0 Serine dehydratase beta chain SANTA PF09133.5 EPR78686.1 - 1.9e-08 34.1 0.6 1.4e-07 31.3 0.4 2.6 1 1 0 1 1 1 1 SANTA (SANT Associated) UPF0020 PF01170.13 EPR78687.1 - 8.9e-10 38.4 0.1 2.8e-09 36.8 0.1 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EPR78687.1 - 0.00039 19.5 0.2 0.00081 18.5 0.0 1.7 2 0 0 2 2 2 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EPR78687.1 - 0.00092 18.7 0.0 0.023 14.2 0.0 2.9 3 1 0 3 3 3 1 DNA methylase Methyltransf_26 PF13659.1 EPR78687.1 - 0.088 12.8 0.0 1 9.3 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L6 PF00347.18 EPR78688.1 - 2.7e-16 59.8 0.9 7.3e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 EPR78688.1 - 0.052 13.6 0.6 0.15 12.1 0.2 1.8 2 0 0 2 2 2 0 YbbR-like protein zf-CSL PF05207.8 EPR78689.1 - 3.9e-20 71.1 2.1 6.3e-20 70.4 1.5 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EPR78689.1 - 0.042 13.4 0.3 0.072 12.6 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPR78689.1 - 0.071 12.8 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DUF164 PF02591.10 EPR78689.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain Zn-ribbon_8 PF09723.5 EPR78689.1 - 0.11 12.5 0.8 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain GATA PF00320.22 EPR78690.1 - 5.5e-09 35.2 5.0 5.5e-09 35.2 3.5 2.5 2 0 0 2 2 2 1 GATA zinc finger DUF3090 PF11290.3 EPR78690.1 - 0.065 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) Sas10_Utp3 PF04000.10 EPR78691.1 - 0.031 14.4 1.8 0.031 14.4 1.2 2.2 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Sas10 PF09368.5 EPR78691.1 - 0.12 12.6 5.1 0.3 11.2 3.5 1.7 1 0 0 1 1 1 0 Sas10 C-terminal domain HTH_28 PF13518.1 EPR78692.1 - 0.012 15.6 0.2 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Fib_alpha PF08702.5 EPR78692.1 - 0.21 11.6 2.8 0.22 11.6 0.3 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Maf1 PF09174.5 EPR78693.1 - 1.1e-07 31.9 11.2 1.4e-07 31.5 7.8 1.2 1 0 0 1 1 1 1 Maf1 regulator DUF3986 PF13143.1 EPR78693.1 - 0.12 12.8 0.4 0.12 12.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) Vps39_1 PF10366.4 EPR78693.1 - 2.3 8.2 8.3 0.099 12.6 1.1 2.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 NAP PF00956.13 EPR78694.1 - 0.0002 20.5 7.4 0.00025 20.2 5.1 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Kri1 PF05178.7 EPR78694.1 - 0.015 15.5 2.3 0.019 15.1 0.9 1.7 2 0 0 2 2 2 0 KRI1-like family Arrestin_N PF00339.24 EPR78696.1 - 7.2e-11 42.1 1.2 1.3e-06 28.2 0.3 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPR78696.1 - 6e-08 32.8 4.6 2.1e-07 31.1 3.2 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Med21 PF11221.3 EPR78697.1 - 0.41 10.6 15.4 0.77 9.7 3.6 3.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex RPN7 PF10602.4 EPR78698.1 - 9.5e-30 103.2 5.6 1.6e-29 102.5 3.9 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EPR78698.1 - 2.2e-08 34.3 3.2 2.2e-08 34.3 2.2 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EPR78698.1 - 5.6e-05 22.9 2.4 5.9e-05 22.8 0.6 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Claudin_2 PF13903.1 EPR78699.1 - 0.078 12.6 0.9 0.14 11.8 0.6 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF912 PF06024.7 EPR78699.1 - 0.28 11.2 10.9 9.9 6.2 7.6 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sec20 PF03908.8 EPR78699.1 - 1.6 8.5 7.6 7.4 6.3 2.4 3.3 3 1 0 3 3 3 0 Sec20 Presenilin PF01080.12 EPR78699.1 - 1.8 7.2 5.2 2.7 6.7 3.6 1.3 1 0 0 1 1 1 0 Presenilin STE PF02200.11 EPR78700.1 - 3.2e-56 188.1 0.4 6.6e-56 187.1 0.3 1.5 1 0 0 1 1 1 1 STE like transcription factor zf-RING_UBOX PF13445.1 EPR78703.1 - 2.2e-09 36.8 7.1 5.2e-09 35.6 4.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EPR78703.1 - 0.14 12.0 5.6 0.27 11.1 3.9 1.5 1 0 0 1 1 1 0 Ring finger domain MEDS PF14417.1 EPR78703.1 - 0.55 9.2 6.4 4 6.4 1.3 2.4 2 1 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Thioredoxin_6 PF13848.1 EPR78704.1 - 9.5e-15 54.8 13.9 6.1e-11 42.4 3.7 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 EPR78704.1 - 1.4e-14 53.5 3.5 4.3e-12 45.6 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_9 PF14595.1 EPR78704.1 - 2.5e-05 23.8 3.7 0.00086 18.8 0.1 3.3 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.1 EPR78704.1 - 0.00019 21.4 2.9 0.022 14.8 0.1 4.7 2 2 1 3 3 3 1 Thioredoxin-like DUF836 PF05768.9 EPR78704.1 - 0.001 19.2 0.0 0.0038 17.4 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EPR78704.1 - 0.0052 16.7 0.0 0.024 14.6 0.0 2.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EPR78704.1 - 0.068 13.3 1.0 1.1 9.4 0.1 3.2 2 2 0 2 2 2 0 Thioredoxin-like domain TMEM156 PF15106.1 EPR78705.1 - 2.8 7.1 9.4 0.19 10.9 1.2 2.1 1 1 1 2 2 2 0 TMEM156 protein family NfeD PF01957.13 EPR78705.1 - 4.2 7.5 4.9 13 5.9 0.1 2.8 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding DUF1129 PF06570.6 EPR78705.1 - 5.1 6.3 7.4 8.2 5.6 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) TRAPP PF04051.11 EPR78707.1 - 1.6e-08 34.2 0.1 1.9e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component cNMP_binding PF00027.24 EPR78709.1 - 4.9e-13 48.7 0.0 1.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Nuc_sug_transp PF04142.10 EPR78710.1 - 0.0022 17.1 2.8 0.0022 17.1 1.9 2.9 2 2 1 3 3 3 2 Nucleotide-sugar transporter EamA PF00892.15 EPR78710.1 - 0.0038 17.2 4.7 0.0038 17.2 3.3 4.0 1 1 4 5 5 5 2 EamA-like transporter family TPT PF03151.11 EPR78710.1 - 0.0063 16.1 25.6 0.021 14.4 5.2 4.0 3 2 0 3 3 3 2 Triose-phosphate Transporter family MAP1B_neuraxin PF00414.12 EPR78711.1 - 1.2 8.5 6.8 0.15 11.4 1.7 1.7 2 0 0 2 2 2 0 Neuraxin and MAP1B repeat PQQ_3 PF13570.1 EPR78712.1 - 0.034 14.4 2.4 35 4.8 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain DUF4549 PF15082.1 EPR78712.1 - 0.049 13.2 0.7 0.049 13.2 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) DUF2147 PF09917.4 EPR78712.1 - 0.78 10.0 5.9 4.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) DUF1246 PF06849.7 EPR78713.1 - 0.011 15.5 1.0 0.03 14.0 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1246) Rad60-SLD PF11976.3 EPR78713.1 - 0.024 14.3 3.0 0.024 14.3 2.1 3.1 3 2 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like COG5 PF10392.4 EPR78713.1 - 0.072 13.0 2.5 0.1 12.5 0.7 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 SDH_beta PF03315.10 EPR78713.1 - 0.78 9.7 2.4 4.2 7.4 0.6 2.2 2 0 0 2 2 2 0 Serine dehydratase beta chain AAA_23 PF13476.1 EPR78714.1 - 6.2e-22 78.9 22.4 6.2e-22 78.9 15.5 8.5 1 1 5 6 6 6 1 AAA domain SMC_N PF02463.14 EPR78714.1 - 7.5e-11 41.6 0.8 7.5e-11 41.6 0.6 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EPR78714.1 - 3.6e-06 26.7 0.0 8.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EPR78714.1 - 0.00013 21.4 0.1 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EPR78714.1 - 0.00029 20.8 12.7 0.00029 20.8 8.8 8.0 1 1 6 7 7 7 1 AAA domain AAA_13 PF13166.1 EPR78714.1 - 0.0016 16.9 4.6 0.0016 16.9 3.2 8.1 1 1 7 8 8 8 2 AAA domain AAA_16 PF13191.1 EPR78714.1 - 0.097 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EPR78714.1 - 0.31 10.8 0.0 0.6 9.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain RNase_PH_C PF03725.10 EPR78715.1 - 0.00016 21.5 0.1 0.00034 20.5 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1310 PF07006.6 EPR78715.1 - 0.033 13.7 2.5 0.065 12.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) RNase_PH PF01138.16 EPR78715.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 AAA PF00004.24 EPR78716.1 - 3.1e-59 198.9 0.4 5.2e-46 156.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPR78716.1 - 5.2e-12 45.7 3.2 6.8e-06 26.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EPR78716.1 - 2.2e-10 41.4 0.4 0.00096 19.9 0.0 2.8 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EPR78716.1 - 7.4e-09 34.9 0.0 0.00038 19.5 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPR78716.1 - 2.1e-08 34.3 7.2 0.011 15.8 0.1 4.3 2 2 2 4 4 4 3 AAA domain AAA_5 PF07728.9 EPR78716.1 - 2.7e-08 33.6 2.3 0.0024 17.5 0.0 4.4 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EPR78716.1 - 2.9e-07 30.0 0.0 0.0053 16.1 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 EPR78716.1 - 1.9e-06 28.2 0.0 0.0014 18.9 0.0 2.7 2 1 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EPR78716.1 - 2.5e-06 27.6 0.0 0.056 13.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 EPR78716.1 - 5.4e-06 26.4 0.0 5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 EPR78716.1 - 1.3e-05 25.2 0.0 0.21 11.5 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EPR78716.1 - 2.1e-05 24.0 0.3 0.065 12.7 0.0 3.5 3 1 0 3 3 3 1 Sigma-54 interaction domain NACHT PF05729.7 EPR78716.1 - 2.4e-05 24.0 0.2 0.024 14.3 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 EPR78716.1 - 2.7e-05 24.5 2.1 0.022 15.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPR78716.1 - 0.00018 21.3 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPR78716.1 - 0.0003 20.8 4.7 0.0061 16.5 0.1 3.7 2 2 2 4 4 4 1 AAA ATPase domain DUF815 PF05673.8 EPR78716.1 - 0.0012 17.8 0.1 0.025 13.5 0.0 2.8 2 2 1 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EPR78716.1 - 0.0013 18.2 0.0 0.94 8.8 0.0 2.9 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 EPR78716.1 - 0.0013 17.9 0.1 0.0095 15.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EPR78716.1 - 0.0019 16.9 0.1 0.019 13.7 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 EPR78716.1 - 0.0026 17.4 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EPR78716.1 - 0.0036 17.1 0.9 1.5 8.5 0.0 3.1 1 1 2 3 3 3 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.13 EPR78716.1 - 0.01 15.4 0.9 0.42 10.2 0.0 3.2 2 1 0 2 2 2 0 Bacterial dnaA protein Viral_helicase1 PF01443.13 EPR78716.1 - 0.011 15.3 0.0 0.041 13.3 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EPR78716.1 - 0.011 15.3 0.0 0.39 10.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EPR78716.1 - 0.012 14.5 0.1 1.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EPR78716.1 - 0.013 14.6 0.0 0.07 12.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AFG1_ATPase PF03969.11 EPR78716.1 - 0.013 14.3 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase DUF258 PF03193.11 EPR78716.1 - 0.023 13.9 0.1 7.8 5.6 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function, DUF258 PhoH PF02562.11 EPR78716.1 - 0.034 13.3 0.3 0.54 9.4 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein NB-ARC PF00931.17 EPR78716.1 - 0.042 12.7 0.0 0.29 9.9 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain ATP-synt_ab PF00006.20 EPR78716.1 - 0.048 13.1 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PPV_E1_C PF00519.12 EPR78716.1 - 0.054 12.1 1.0 1.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_28 PF13521.1 EPR78716.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EPR78716.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 EPR78716.1 - 0.14 11.7 0.1 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EPR78716.1 - 0.21 11.3 6.6 11 5.6 0.0 4.7 3 2 2 5 5 5 0 NTPase Pox_Ag35 PF03286.9 EPR78717.1 - 0.37 10.2 6.5 0.53 9.7 4.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tup_N PF08581.5 EPR78718.1 - 6.2e-05 23.1 4.7 0.00021 21.3 3.3 2.0 1 0 0 1 1 1 1 Tup N-terminal WD40 PF00400.27 EPR78718.1 - 0.00017 21.3 6.9 0.34 10.8 0.0 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat Prp19 PF08606.6 EPR78718.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like HALZ PF02183.13 EPR78718.1 - 0.79 9.4 4.1 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glutaredoxin PF00462.19 EPR78719.1 - 2.3e-09 37.0 0.1 5.3e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 EPR78719.1 - 6e-05 23.2 0.5 8.1e-05 22.8 0.4 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) ArsC PF03960.10 EPR78719.1 - 0.14 12.2 1.6 0.33 11.0 0.1 1.9 1 1 1 2 2 2 0 ArsC family DASH_Dad4 PF08650.5 EPR78719.1 - 1.9 8.4 6.4 0.75 9.7 0.1 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad4 SprA-related PF12118.3 EPR78721.1 - 0.021 14.1 1.2 0.026 13.8 0.8 1.1 1 0 0 1 1 1 0 SprA-related family CDC45 PF02724.9 EPR78721.1 - 0.15 10.0 4.4 0.19 9.7 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L18ae PF01775.12 EPR78722.1 - 1.2e-27 96.2 1.5 1.2e-27 96.2 1.1 1.5 2 0 0 2 2 2 1 Ribosomal L18ae/LX protein domain EamA PF00892.15 EPR78723.1 - 0.0025 17.8 7.3 0.0025 17.8 5.0 3.4 2 1 1 3 3 3 1 EamA-like transporter family Fibrillarin PF01269.12 EPR78725.1 - 1.4e-110 367.6 0.0 1.6e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EPR78725.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPR78725.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF461 PF04314.8 EPR78725.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF461) DUF3040 PF11239.3 EPR78726.1 - 0.83 9.7 7.7 0.54 10.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PIRT PF15099.1 EPR78726.1 - 8.8 5.5 7.1 0.31 10.2 0.8 1.8 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family RabGAP-TBC PF00566.13 EPR78727.1 - 1.1e-08 34.8 9.3 8.7e-08 31.8 6.4 2.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Brix PF04427.13 EPR78728.1 - 1.7e-23 83.2 1.8 2.9e-23 82.5 1.3 1.3 1 0 0 1 1 1 1 Brix domain DUF2951 PF11166.3 EPR78728.1 - 5.5 6.9 10.0 4.5 7.1 2.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) HSBP1 PF06825.7 EPR78729.1 - 1.1 8.8 9.3 2.7 7.6 0.8 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Ribosomal_L34e PF01199.13 EPR78730.1 - 1.2e-31 108.7 4.8 1.4e-31 108.5 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e FYVE PF01363.16 EPR78730.1 - 0.056 13.3 0.9 0.11 12.4 0.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger HIT PF01230.18 EPR78731.1 - 5.6e-21 74.9 2.2 7.2e-21 74.5 1.5 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPR78731.1 - 2e-11 44.1 3.1 2.8e-11 43.6 2.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPR78731.1 - 8e-07 28.7 2.6 1.1e-06 28.3 1.8 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pneumo_NS1 PF03438.8 EPR78731.1 - 0.035 13.9 0.3 0.07 12.9 0.2 1.6 1 1 0 1 1 1 0 Pneumovirus NS1 protein AAA_12 PF13087.1 EPR78732.1 - 7.7e-33 113.5 2.2 7.7e-33 113.5 1.5 2.9 4 0 0 4 4 4 1 AAA domain AAA_11 PF13086.1 EPR78732.1 - 9e-12 45.0 9.3 1.7e-05 24.5 0.1 3.5 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 EPR78732.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPR78732.1 - 0.00026 20.5 0.0 0.93 8.9 0.0 2.8 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EPR78732.1 - 0.001 19.1 0.2 0.064 13.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPR78732.1 - 0.042 13.6 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EPR78732.1 - 0.5 10.3 0.0 1.1 9.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC1 PF03109.11 EPR78733.1 - 1.7e-11 44.1 0.0 6.2e-11 42.3 0.0 1.9 2 1 1 3 3 3 1 ABC1 family PfkB PF00294.19 EPR78733.1 - 0.043 12.9 0.2 0.043 12.9 0.1 1.8 2 0 0 2 2 2 0 pfkB family carbohydrate kinase SNF2_N PF00176.18 EPR78734.1 - 2.3e-47 161.2 3.9 8.9e-47 159.3 2.7 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPR78734.1 - 1e-12 47.7 0.9 2.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPR78734.1 - 0.0032 16.9 0.0 0.047 13.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Proteasome PF00227.21 EPR78736.1 - 2.7e-34 118.1 0.0 3.4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 EPR78737.1 - 4.2e-27 94.9 4.1 8.4e-27 93.9 2.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78737.1 - 6.9e-21 74.4 1.0 5e-20 71.6 0.2 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR78737.1 - 0.022 13.7 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SWIB PF02201.13 EPR78738.1 - 0.11 12.1 2.0 0.25 11.0 1.4 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain ABC2_membrane_3 PF12698.2 EPR78739.1 - 0.0034 16.4 2.3 0.0042 16.1 1.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein 7tm_6 PF02949.15 EPR78739.1 - 0.01 14.6 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor DUF3440 PF11922.3 EPR78739.1 - 0.88 9.0 5.3 16 5.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Tom22 PF04281.8 EPR78739.1 - 6.4 6.3 6.7 4.8 6.7 3.1 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ribosomal_L7Ae PF01248.21 EPR78740.1 - 1.9e-13 49.7 0.7 2.3e-13 49.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1694 PF07997.6 EPR78740.1 - 0.049 13.5 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Hpr_kinase_N PF02603.11 EPR78740.1 - 0.098 12.3 0.1 0.2 11.3 0.1 1.5 2 0 0 2 2 2 0 HPr Serine kinase N terminus Med18 PF09637.5 EPR78742.1 - 0.038 13.5 1.9 0.047 13.2 1.3 1.2 1 0 0 1 1 1 0 Med18 protein DUF257 PF03192.8 EPR78742.1 - 0.098 11.9 10.7 0.13 11.5 7.4 1.3 1 1 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 AAA_21 PF13304.1 EPR78742.1 - 0.13 12.2 14.5 0.16 11.9 10.0 1.1 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 EPR78742.1 - 0.54 10.0 13.7 0.059 13.1 4.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF223 PF02721.9 EPR78742.1 - 0.55 10.3 5.3 1.5 8.9 3.0 2.1 1 1 0 1 1 1 0 Domain of unknown function DUF223 Mgr1 PF08602.5 EPR78742.1 - 1.4 7.8 8.3 1.6 7.6 5.8 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF1980 PF09323.5 EPR78742.1 - 1.5 8.5 13.5 0.074 12.7 5.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Flu_NS2 PF00601.14 EPR78742.1 - 2.2 8.5 7.5 1.6 8.9 2.2 2.5 1 1 2 3 3 3 0 Influenza non-structural protein (NS2) Yippee-Mis18 PF03226.9 EPR78744.1 - 0.00015 21.7 2.9 0.0062 16.5 2.0 2.4 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SEA PF01390.15 EPR78744.1 - 0.0032 17.1 0.3 0.0045 16.6 0.2 1.2 1 0 0 1 1 1 1 SEA domain RNase_T PF00929.19 EPR78745.1 - 2.6e-24 86.3 2.2 2.8e-24 86.2 0.4 1.9 2 0 0 2 2 2 1 Exonuclease Ribosomal_L18e PF00828.14 EPR78747.1 - 4.5e-10 39.9 0.5 7.8e-10 39.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aminotran_5 PF00266.14 EPR78748.1 - 6.6e-83 278.4 0.0 7.8e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPR78748.1 - 2.7e-06 26.6 0.0 7.5e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPR78748.1 - 3.8e-06 26.2 0.0 5.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 EPR78748.1 - 2.6e-05 22.8 0.0 4.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain HTH_40 PF14493.1 EPR78748.1 - 0.00044 20.4 0.3 1.4 9.1 0.0 3.0 3 0 0 3 3 3 2 Helix-turn-helix domain DegT_DnrJ_EryC1 PF01041.12 EPR78748.1 - 0.0027 16.8 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family UCH PF00443.24 EPR78749.1 - 8.9e-07 28.2 1.6 0.0022 17.1 0.7 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF1664 PF07889.7 EPR78749.1 - 0.096 12.4 0.5 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2663 PF10864.3 EPR78749.1 - 0.21 11.8 4.5 3.1 8.0 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) LSM PF01423.17 EPR78750.1 - 2.4e-12 46.1 2.3 2.8e-12 46.0 1.6 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 EPR78750.1 - 0.0014 18.4 0.7 0.0015 18.3 0.5 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Hydrolase PF00702.21 EPR78751.1 - 4.6e-16 59.8 0.0 3.1e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPR78751.1 - 1e-13 51.8 0.3 2.2e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPR78751.1 - 2.6e-10 39.7 0.0 2.6e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPR78751.1 - 6.6e-06 26.0 0.0 5.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Pyr_redox_3 PF13738.1 EPR78752.1 - 2.8e-06 27.5 0.0 0.0058 16.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPR78752.1 - 4.2e-06 26.7 0.0 0.0033 17.3 0.0 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPR78752.1 - 0.00012 22.4 0.0 0.15 12.4 0.0 3.4 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPR78752.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EPR78752.1 - 0.0073 14.5 5.9 0.028 12.6 4.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EPR78752.1 - 0.012 15.7 1.2 0.12 12.4 0.0 2.9 2 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EPR78752.1 - 0.016 15.0 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPR78752.1 - 0.016 14.1 0.0 0.23 10.3 0.1 2.6 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HTH_19 PF12844.2 EPR78752.1 - 0.21 11.6 7.4 0.094 12.7 1.5 3.2 4 1 0 4 4 4 0 Helix-turn-helix domain GIT_SHD PF08518.6 EPR78753.1 - 1e-06 27.9 5.9 0.00023 20.4 0.5 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Protoglobin PF11563.3 EPR78753.1 - 0.013 15.1 1.0 0.084 12.5 0.0 2.4 1 1 2 3 3 3 0 Protoglobin AAA PF00004.24 EPR78754.1 - 5.5e-20 71.9 0.2 5.3e-19 68.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EPR78754.1 - 1.7e-15 57.0 8.5 2.6e-15 56.4 0.4 3.2 2 2 1 3 3 3 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EPR78754.1 - 1.1e-09 38.3 0.4 2.6e-09 37.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EPR78754.1 - 1.8e-08 34.5 0.3 0.0059 16.7 0.1 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EPR78754.1 - 2.7e-07 29.8 0.0 6.5e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPR78754.1 - 2.8e-07 30.3 0.1 1.4e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EPR78754.1 - 7.8e-07 28.9 0.7 1.2e-06 28.2 0.5 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPR78754.1 - 3.4e-06 27.1 0.0 0.00053 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EPR78754.1 - 3.9e-06 27.0 11.5 5.2e-06 26.6 7.9 1.1 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPR78754.1 - 1.5e-05 24.2 0.0 0.0061 15.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EPR78754.1 - 3.7e-05 24.5 0.6 0.00035 21.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EPR78754.1 - 6e-05 21.9 8.5 0.0011 17.8 0.0 2.3 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EPR78754.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EPR78754.1 - 0.00027 21.2 2.0 0.0011 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Rep_fac_C PF08542.6 EPR78754.1 - 0.00027 20.8 0.6 0.00085 19.2 0.4 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Sigma54_activat PF00158.21 EPR78754.1 - 0.0011 18.5 0.0 0.64 9.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.1 EPR78754.1 - 0.0027 17.3 0.2 0.24 10.9 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EPR78754.1 - 0.0033 17.0 0.3 0.0083 15.7 0.2 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EPR78754.1 - 0.0037 17.3 0.0 0.015 15.3 0.0 2.0 2 1 0 2 2 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 EPR78754.1 - 0.0066 16.7 2.4 0.018 15.3 1.7 2.1 1 1 0 1 1 1 1 ABC transporter Viral_helicase1 PF01443.13 EPR78754.1 - 0.0075 15.8 0.0 0.024 14.1 0.0 1.8 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EPR78754.1 - 0.0082 15.9 0.5 0.02 14.7 0.3 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mrr_cat PF04471.7 EPR78754.1 - 0.0088 15.8 0.0 0.41 10.4 0.0 2.4 2 0 0 2 2 2 1 Restriction endonuclease RNA_helicase PF00910.17 EPR78754.1 - 0.0089 16.1 0.3 0.056 13.6 0.0 2.4 1 1 1 2 2 2 1 RNA helicase DNA_pol3_delta PF06144.8 EPR78754.1 - 0.0099 15.4 1.4 0.0099 15.4 1.0 1.7 2 0 0 2 2 1 1 DNA polymerase III, delta subunit T2SE PF00437.15 EPR78754.1 - 0.012 14.5 0.0 0.031 13.1 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 EPR78754.1 - 0.022 13.6 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EPR78754.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPR78754.1 - 0.026 14.2 1.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 NTPase Elong_Iki1 PF10483.4 EPR78754.1 - 0.026 13.8 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Elongator subunit Iki1 DEAD PF00270.24 EPR78754.1 - 0.026 14.0 0.1 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_10 PF12846.2 EPR78754.1 - 0.046 13.1 0.2 0.69 9.2 0.0 2.2 1 1 1 3 3 3 0 AAA-like domain DED PF01335.16 EPR78754.1 - 0.081 13.0 0.2 0.21 11.7 0.1 1.7 1 1 0 1 1 1 0 Death effector domain AAA_23 PF13476.1 EPR78754.1 - 0.092 13.0 16.9 0.17 12.1 11.7 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPR78754.1 - 0.11 11.9 2.3 0.93 8.8 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein HrcA_DNA-bdg PF03444.10 EPR78754.1 - 0.17 11.3 5.2 3.3 7.2 0.2 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PhoU_div PF01865.11 EPR78754.1 - 0.28 10.3 10.0 0.022 13.9 2.8 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF47 RPW8 PF05659.6 EPR78754.1 - 0.3 10.6 5.1 0.59 9.6 0.1 2.9 1 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Transglut_i_TM PF14400.1 EPR78754.1 - 0.34 10.3 1.4 1 8.8 0.0 2.2 3 0 0 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices NUDIX PF00293.23 EPR78755.1 - 5.5e-16 58.4 0.0 1.3e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 EPR78755.1 - 3.8e-06 26.6 0.3 1.9e-05 24.4 0.1 2.2 2 0 0 2 2 2 1 Dcp2, box A domain ATP_bind_1 PF03029.12 EPR78756.1 - 6.2e-28 97.9 0.7 9.1e-28 97.4 0.5 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EPR78756.1 - 4.4e-06 26.6 1.4 1.5e-05 24.9 1.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_11 PF13086.1 EPR78756.1 - 0.0003 20.4 0.0 0.00062 19.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPR78756.1 - 0.0017 17.8 0.3 0.0054 16.2 0.0 1.9 2 1 0 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 EPR78756.1 - 0.0019 17.9 0.9 0.0019 17.9 0.7 2.3 1 1 1 2 2 2 1 Archaeal ATPase FeoB_N PF02421.13 EPR78756.1 - 0.0036 16.6 2.7 0.02 14.2 0.9 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPR78756.1 - 0.0049 16.3 0.2 0.008 15.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPR78756.1 - 0.012 15.7 0.5 0.023 14.8 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPR78756.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EPR78756.1 - 0.023 14.4 0.1 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPR78756.1 - 0.024 14.5 0.6 0.024 14.5 0.4 3.1 1 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 EPR78756.1 - 0.034 14.0 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPR78756.1 - 0.052 14.3 0.3 0.052 14.3 0.2 2.5 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPR78756.1 - 0.061 13.5 0.2 0.44 10.7 0.2 2.5 1 1 0 1 1 1 0 RNA helicase MobB PF03205.9 EPR78756.1 - 0.091 12.4 0.2 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EPR78756.1 - 0.12 12.6 3.9 1.3 9.3 2.7 2.5 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EPR78756.1 - 0.28 11.6 2.5 1.4 9.4 0.4 2.7 3 1 0 3 3 1 0 Miro-like protein HATPase_c_3 PF13589.1 EPR78757.1 - 5.2e-17 61.7 1.1 5.2e-17 61.7 0.7 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPR78757.1 - 5.4e-10 38.9 0.1 1.4e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 PF00183.13 EPR78757.1 - 3.5e-09 35.6 0.9 3.5e-09 35.6 0.6 4.3 2 1 2 4 4 4 2 Hsp90 protein EF-hand_7 PF13499.1 EPR78759.1 - 2.3e-15 56.4 0.3 7.3e-10 38.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EPR78759.1 - 5.9e-15 53.3 6.1 3.4e-06 25.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EPR78759.1 - 1.4e-12 46.3 0.8 0.0043 16.8 0.1 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EPR78759.1 - 1.4e-09 37.4 3.1 2.9e-06 26.7 0.2 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EPR78759.1 - 1.6e-09 36.6 3.9 0.00023 20.3 0.1 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EPR78759.1 - 0.013 15.1 0.1 0.043 13.5 0.0 1.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Sen15 PF09631.5 EPR78759.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Sen15 protein GATA PF00320.22 EPR78761.1 - 5e-18 64.1 13.2 8.4e-14 50.6 3.1 2.4 2 0 0 2 2 2 2 GATA zinc finger CG-1 PF03859.11 EPR78761.1 - 0.0061 16.0 2.2 0.0061 16.0 1.5 2.4 2 1 0 2 2 2 1 CG-1 domain Zn-ribbon_8 PF09723.5 EPR78761.1 - 1.2 9.1 4.9 2.6 8.0 0.2 2.7 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EPR78761.1 - 3.1 7.6 7.8 75 3.2 5.5 2.5 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 EPR78762.1 - 5.3e-15 55.2 0.7 7.5e-15 54.7 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78762.1 - 9.5e-07 28.1 0.1 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HMG_box PF00505.14 EPR78763.1 - 3.9e-19 68.6 12.6 1.2e-11 44.6 3.2 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EPR78763.1 - 4.4e-19 68.6 17.5 1.3e-14 54.3 5.1 2.5 2 1 0 2 2 2 2 HMG-box domain YABBY PF04690.8 EPR78763.1 - 1.7e-05 25.1 4.4 2.3e-05 24.7 3.0 1.2 1 0 0 1 1 1 1 YABBY protein CAT PF00302.13 EPR78763.1 - 0.012 15.2 0.8 0.012 15.2 0.5 1.8 1 1 0 2 2 2 0 Chloramphenicol acetyltransferase DUF3106 PF11304.3 EPR78763.1 - 0.22 11.9 14.9 0.73 10.2 0.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3106) DUF1965 PF09248.5 EPR78763.1 - 0.64 9.9 5.3 4.9 7.1 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1965) DUF2924 PF11149.3 EPR78763.1 - 2.8 7.9 7.3 6.8 6.7 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2924) MADF_DNA_bdg PF10545.4 EPR78763.1 - 4.2 7.6 11.5 9 6.5 4.9 2.6 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Xpo1 PF08389.7 EPR78764.1 - 0.00014 21.8 5.7 0.00036 20.4 0.1 3.4 2 1 0 2 2 2 1 Exportin 1-like protein Pkinase PF00069.20 EPR78765.1 - 4.6e-35 121.0 0.5 7.1e-35 120.4 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78765.1 - 2.2e-21 76.0 0.0 6.9e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EPR78765.1 - 3.3e-07 29.8 0.2 6.1e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPR78765.1 - 3.8e-05 22.8 0.1 6.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR78765.1 - 0.00033 20.4 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPR78765.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 EPR78765.1 - 0.037 12.8 4.6 0.049 12.4 2.6 1.5 1 1 1 2 2 2 0 Seadornavirus VP7 TFIIE_alpha PF02002.12 EPR78766.1 - 4.5e-09 35.7 5.2 4.5e-09 35.7 3.6 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 EPR78766.1 - 0.017 15.0 1.3 0.55 10.2 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.9 EPR78766.1 - 0.27 10.9 1.3 0.83 9.3 0.9 1.9 1 1 0 1 1 1 0 Adenylate kinase, active site lid GOLD_2 PF13897.1 EPR78766.1 - 4.1 7.6 10.1 1.5 9.0 4.6 2.0 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Nup35_RRM_2 PF14605.1 EPR78767.1 - 4.8e-05 23.0 0.8 9e-05 22.1 0.2 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EPR78767.1 - 0.00094 18.8 0.8 0.017 14.8 0.5 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.1 EPR78767.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) DUF2089 PF09862.4 EPR78767.1 - 0.3 10.8 2.2 1.4 8.6 0.2 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2089) HTH_29 PF13551.1 EPR78768.1 - 4.9e-15 55.6 0.0 2.5e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Winged helix-turn helix HTH_24 PF13412.1 EPR78768.1 - 1.6e-12 46.5 0.6 0.00038 19.7 0.0 3.9 4 0 0 4 4 4 2 Winged helix-turn-helix DNA-binding HTH_38 PF13936.1 EPR78768.1 - 4.2e-11 42.2 0.5 9.5e-05 21.8 0.0 3.6 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_28 PF13518.1 EPR78768.1 - 9e-11 41.5 0.0 0.00057 19.8 0.0 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 EPR78768.1 - 1e-09 39.0 0.0 3.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.1 EPR78768.1 - 1e-09 37.7 0.1 0.004 16.7 0.0 3.6 4 0 0 4 4 4 2 Homeodomain-like domain MarR_2 PF12802.2 EPR78768.1 - 2.6e-09 36.6 0.0 0.0006 19.4 0.0 2.4 2 0 0 2 2 2 2 MarR family TrmB PF01978.14 EPR78768.1 - 4e-09 36.0 0.1 0.0015 18.1 0.0 2.6 2 0 0 2 2 2 2 Sugar-specific transcriptional regulator TrmB HTH_Tnp_Tc3_2 PF01498.13 EPR78768.1 - 8.5e-08 32.1 0.4 0.00022 21.2 0.0 3.9 3 1 1 4 4 4 1 Transposase MarR PF01047.17 EPR78768.1 - 1.4e-07 31.1 1.1 0.011 15.4 0.0 3.0 3 0 0 3 3 3 2 MarR family Penicillinase_R PF03965.11 EPR78768.1 - 2.3e-07 30.9 0.0 0.069 13.2 0.0 3.2 3 0 0 3 3 3 2 Penicillinase repressor HTH_40 PF14493.1 EPR78768.1 - 4.1e-06 26.9 0.1 0.033 14.3 0.0 2.8 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_Mga PF08280.6 EPR78768.1 - 1.8e-05 24.4 0.0 0.17 11.6 0.0 2.9 3 0 0 3 3 2 2 M protein trans-acting positive regulator (MGA) HTH domain HTH_AsnC-type PF13404.1 EPR78768.1 - 4.4e-05 22.9 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 AsnC-type helix-turn-helix domain HTH_Crp_2 PF13545.1 EPR78768.1 - 5.7e-05 22.8 0.0 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 Crp-like helix-turn-helix domain Fe_dep_repress PF01325.14 EPR78768.1 - 8.4e-05 22.4 0.2 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 Iron dependent repressor, N-terminal DNA binding domain HTH_10 PF04967.7 EPR78768.1 - 0.00011 21.6 0.0 0.61 9.7 0.0 2.5 2 0 0 2 2 2 2 HTH DNA binding domain HTH_IclR PF09339.5 EPR78768.1 - 0.00011 21.6 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 IclR helix-turn-helix domain Sigma70_r4 PF04545.11 EPR78768.1 - 0.00015 21.0 0.0 0.58 9.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_11 PF08279.7 EPR78768.1 - 0.00027 20.5 0.7 4.3 7.0 0.0 3.6 3 0 0 3 3 3 0 HTH domain KH_5 PF13184.1 EPR78768.1 - 0.00033 20.3 1.0 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 NusA-like KH domain Sigma70_r4_2 PF08281.7 EPR78768.1 - 0.0011 18.4 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 DUF3221 PF11518.3 EPR78768.1 - 0.0019 17.8 0.6 1.5 8.4 0.0 2.8 1 1 0 2 2 2 2 Protein of unknown function (DUF3221) HTH_41 PF14502.1 EPR78768.1 - 0.0024 17.4 1.1 1.3 8.6 0.1 2.5 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_34 PF13601.1 EPR78768.1 - 0.003 17.5 0.2 3.7 7.6 0.0 2.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain Terminase_5 PF06056.7 EPR78768.1 - 0.0032 16.9 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Putative ATPase subunit of terminase (gpP-like) HTH_3 PF01381.17 EPR78768.1 - 0.0033 17.2 0.2 1.3 8.8 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix CENP-B_N PF04218.8 EPR78768.1 - 0.0036 16.7 0.5 1.8 8.0 0.0 2.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.10 EPR78768.1 - 0.0059 16.4 0.4 0.26 11.1 0.0 3.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Mga PF05043.8 EPR78768.1 - 0.011 16.0 7.1 2.3 8.5 0.3 3.7 3 1 0 3 3 3 0 Mga helix-turn-helix domain HTH_33 PF13592.1 EPR78768.1 - 0.011 15.2 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix GerE PF00196.14 EPR78768.1 - 0.014 14.6 1.0 5.8 6.3 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF1366 PF07104.6 EPR78768.1 - 0.016 14.8 0.1 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) HTH_CodY PF08222.6 EPR78768.1 - 0.054 12.8 0.1 13 5.2 0.0 2.5 2 0 0 2 2 2 0 CodY helix-turn-helix domain FeoC PF09012.5 EPR78768.1 - 0.083 12.6 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 FeoC like transcriptional regulator LRR_9 PF14580.1 EPR78768.1 - 0.14 11.7 1.6 4.6 6.7 0.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeat HTH_36 PF13730.1 EPR78768.1 - 0.58 10.3 2.9 18 5.5 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain GLYCAM-1 PF05242.6 EPR78769.1 - 0.099 12.5 2.8 0.33 10.8 1.9 1.9 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Glyco_hydro_67N PF03648.9 EPR78769.1 - 0.13 12.3 0.2 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus Nol1_Nop2_Fmu PF01189.12 EPR78770.1 - 4.9e-33 114.7 0.0 7.2e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EPR78770.1 - 4e-06 26.9 0.0 7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase WD40 PF00400.27 EPR78771.1 - 2.5e-18 65.1 4.0 3.2e-08 33.1 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat CK_II_beta PF01214.13 EPR78772.1 - 3.2e-49 166.9 2.4 5.9e-49 166.0 1.7 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit NOT2_3_5 PF04153.13 EPR78774.1 - 2.8e-34 117.8 15.9 5e-34 117.0 11.0 1.7 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2392 PF10288.4 EPR78775.1 - 3.8 7.9 9.5 6.7 7.0 1.6 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2392) Gti1_Pac2 PF09729.4 EPR78776.1 - 2e-08 34.2 3.1 4.4e-08 33.1 0.1 2.2 1 1 1 2 2 2 1 Gti1/Pac2 family ATP_bind_1 PF03029.12 EPR78778.1 - 1.7e-51 175.0 0.3 3.2e-51 174.1 0.2 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPR78778.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EPR78778.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EPR78778.1 - 2.6e-05 23.7 0.0 0.00019 20.9 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 EPR78778.1 - 0.00011 21.7 0.2 0.0049 16.3 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPR78778.1 - 0.00019 21.3 0.6 0.00049 20.0 0.4 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EPR78778.1 - 0.00022 22.0 0.2 0.00042 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EPR78778.1 - 0.00078 18.9 0.2 0.0061 15.9 0.1 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Gtr1_RagA PF04670.7 EPR78778.1 - 0.0035 16.5 0.1 0.17 10.9 0.1 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EPR78778.1 - 0.0036 17.1 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR78778.1 - 0.0041 17.4 0.5 0.0083 16.4 0.1 1.8 2 1 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 EPR78778.1 - 0.0049 16.3 0.6 0.12 11.8 0.0 3.0 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EPR78778.1 - 0.0081 15.8 0.0 0.053 13.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EPR78778.1 - 0.0091 15.4 0.6 0.081 12.3 0.4 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EPR78778.1 - 0.0093 14.8 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 EPR78778.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EPR78778.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EPR78778.1 - 0.019 14.8 0.4 0.08 12.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EPR78778.1 - 0.02 14.1 0.1 0.68 9.1 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EPR78778.1 - 0.02 14.2 0.0 0.049 12.9 0.0 1.6 2 0 0 2 2 1 0 Thymidylate kinase Arf PF00025.16 EPR78778.1 - 0.053 12.7 0.1 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Zeta_toxin PF06414.7 EPR78778.1 - 0.057 12.5 0.0 0.59 9.2 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 EPR78778.1 - 0.066 13.4 0.2 0.46 10.6 0.0 2.3 2 1 0 2 2 2 0 RNA helicase ATP_bind_2 PF03668.10 EPR78778.1 - 0.088 11.8 0.1 0.18 10.8 0.0 1.5 2 0 0 2 2 2 0 P-loop ATPase protein family Viral_helicase1 PF01443.13 EPR78778.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EPR78778.1 - 0.1 12.1 0.2 0.24 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPR78778.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EPR78778.1 - 0.16 11.0 2.2 0.58 9.2 0.2 2.6 2 2 0 2 2 2 0 KaiC Myb_DNA-binding PF00249.26 EPR78779.1 - 6.3e-06 26.1 0.1 2.2e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPR78779.1 - 0.0067 16.5 1.6 0.018 15.0 0.3 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain UPF0542 PF15086.1 EPR78779.1 - 0.009 15.7 3.1 0.013 15.1 0.1 2.2 2 1 0 2 2 2 1 Uncharacterised protein family UPF0542 Phage_Mu_Gam PF07352.7 EPR78779.1 - 3.3 7.2 11.0 5.6 6.4 2.9 2.1 1 1 0 2 2 2 0 Bacteriophage Mu Gam like protein LRR_8 PF13855.1 EPR78782.1 - 1.5e-14 53.4 36.8 1.9e-06 27.5 2.8 5.2 3 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.2 EPR78782.1 - 1.5e-12 46.7 43.4 4.4e-06 26.1 3.4 7.0 6 2 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78782.1 - 1.8e-07 30.2 37.3 0.44 10.7 0.1 9.6 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR78782.1 - 3e-07 29.5 18.0 3.7 8.1 0.0 8.7 9 0 0 9 9 9 4 Leucine rich repeat SAP18 PF06487.7 EPR78782.1 - 0.1 12.3 0.8 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) SPC22 PF04573.7 EPR78783.1 - 2e-11 43.4 9.9 3.9e-10 39.2 6.8 2.0 1 1 0 1 1 1 1 Signal peptidase subunit DUF1371 PF07115.6 EPR78783.1 - 0.19 11.8 4.2 0.34 11.0 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1371) Ank_2 PF12796.2 EPR78784.1 - 7.6e-13 48.6 3.3 1.9e-11 44.1 0.4 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPR78784.1 - 4e-10 39.9 2.9 1.3e-05 25.5 0.4 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPR78784.1 - 2e-09 37.3 0.9 3.5e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EPR78784.1 - 5.9e-08 32.1 2.0 0.0027 17.4 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EPR78784.1 - 2.7e-07 30.1 9.3 9.8e-06 25.3 0.1 4.9 5 0 0 5 5 5 1 Ankyrin repeat zf-DHHC PF01529.15 EPR78784.1 - 1.3e-06 27.9 34.0 1.3e-06 27.9 23.6 2.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase FA_hydroxylase PF04116.8 EPR78784.1 - 0.79 10.1 8.0 0.81 10.1 0.1 2.8 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily TryThrA_C PF12319.3 EPR78784.1 - 3.1 6.9 9.1 0.5 9.5 0.3 2.4 2 0 0 2 2 2 0 Tryptophan-Threonine-rich plasmodium antigen C terminal DDE_Tnp_IS1595 PF12762.2 EPR78785.1 - 1.1e-11 44.7 0.4 1.2e-11 44.6 0.3 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DUF3136 PF11334.3 EPR78785.1 - 0.0098 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3136) NSP11 PF06471.7 EPR78785.1 - 0.031 12.4 0.7 0.031 12.4 0.5 1.0 1 0 0 1 1 1 0 NSP11 RRM_1 PF00076.17 EPR78786.1 - 4.3e-31 106.3 2.1 2e-16 59.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR78786.1 - 5e-21 74.4 0.4 3e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR78786.1 - 2e-12 46.7 0.4 2.4e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPR78786.1 - 5.5e-07 29.2 0.1 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif V_ATPase_I PF01496.14 EPR78787.1 - 3.3e-140 468.3 32.5 4.2e-140 468.0 22.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family B-block_TFIIIC PF04182.7 EPR78787.1 - 0.04 13.7 0.7 0.15 11.9 0.5 2.0 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC AF0941-like PF14591.1 EPR78788.1 - 0.00097 19.2 5.2 0.058 13.4 0.6 2.5 2 0 0 2 2 2 2 AF0941-like SEP PF08059.8 EPR78788.1 - 0.0034 17.6 0.4 0.0096 16.2 0.3 1.8 1 0 0 1 1 1 1 SEP domain ABC2_membrane_3 PF12698.2 EPR78788.1 - 5.3 5.9 6.6 5.8 5.8 4.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein HTH_24 PF13412.1 EPR78789.1 - 0.001 18.3 3.7 0.0026 17.1 2.5 1.7 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EPR78789.1 - 0.0034 17.0 0.4 0.0073 15.9 0.3 1.6 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB DUF2247 PF10004.4 EPR78789.1 - 0.027 14.1 1.1 0.027 14.1 0.8 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) LexA_DNA_bind PF01726.11 EPR78789.1 - 0.13 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 LexA DNA binding domain Cullin_Nedd8 PF10557.4 EPR78789.1 - 0.13 12.0 6.7 1.3 8.9 4.0 2.8 2 1 0 2 2 2 0 Cullin protein neddylation domain Tyrosinase PF00264.15 EPR78789.1 - 0.16 12.1 0.8 0.21 11.7 0.5 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase ABC_tran PF00005.22 EPR78790.1 - 1.5e-13 51.2 0.0 2.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RLI PF04068.10 EPR78790.1 - 6.7e-09 35.1 2.9 6.7e-09 35.1 2.0 2.4 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 EPR78790.1 - 6.6e-07 28.6 11.2 3.5e-06 26.3 2.1 3.3 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_7 PF12838.2 EPR78790.1 - 3.6e-06 27.2 7.6 0.0002 21.6 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 EPR78790.1 - 7.6e-06 25.5 13.4 0.00012 21.8 1.8 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EPR78790.1 - 3.2e-05 23.7 12.4 7.3e-05 22.5 8.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_15 PF13175.1 EPR78790.1 - 0.00017 20.7 3.6 0.00023 20.3 2.5 1.1 1 0 0 1 1 1 1 AAA ATPase domain Fer4_16 PF13484.1 EPR78790.1 - 0.00029 21.5 5.6 0.0013 19.3 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_2 PF12797.2 EPR78790.1 - 0.0043 16.8 2.3 0.0043 16.8 1.6 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_21 PF13304.1 EPR78790.1 - 0.0059 16.6 2.6 0.21 11.5 0.2 2.1 1 1 1 2 2 2 1 AAA domain Fer4_9 PF13187.1 EPR78790.1 - 0.0066 16.6 3.1 0.0066 16.6 2.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EPR78790.1 - 0.0093 15.7 2.6 0.0093 15.7 1.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_29 PF13555.1 EPR78790.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EPR78790.1 - 0.012 15.8 0.5 0.021 15.1 0.4 1.4 1 1 0 1 1 1 0 AAA domain Fer4_11 PF13247.1 EPR78790.1 - 0.025 14.4 5.4 0.047 13.5 3.7 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 EPR78790.1 - 0.026 15.0 4.7 0.026 15.0 3.3 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain DUF258 PF03193.11 EPR78790.1 - 0.056 12.6 0.0 0.056 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Fer4_18 PF13746.1 EPR78790.1 - 0.062 13.7 2.9 0.062 13.7 2.0 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 EPR78790.1 - 0.073 13.4 3.2 0.073 13.4 2.2 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain VirE PF05272.6 EPR78790.1 - 0.14 11.6 0.9 0.38 10.2 0.0 2.1 2 1 0 3 3 3 0 Virulence-associated protein E Fer4_15 PF13459.1 EPR78790.1 - 0.69 10.5 7.1 0.22 12.0 0.5 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_8 PF13183.1 EPR78790.1 - 0.91 9.5 12.9 0.12 12.4 1.8 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain Pox_Ag35 PF03286.9 EPR78791.1 - 5.1 6.5 11.0 6.9 6.1 7.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIS_C PF01096.13 EPR78792.1 - 3.6e-14 52.1 8.6 3.6e-14 52.1 6.0 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 EPR78792.1 - 1.2e-10 41.4 8.2 2.7e-09 37.0 5.7 2.3 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain AF0941-like PF14591.1 EPR78792.1 - 0.47 10.5 9.6 0.13 12.3 2.7 2.6 2 1 1 3 3 3 0 AF0941-like Pkinase PF00069.20 EPR78793.1 - 1.3e-54 185.0 0.5 1.6e-54 184.8 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78793.1 - 2.1e-22 79.4 0.0 3.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPR78793.1 - 3.9e-06 26.7 0.0 0.0021 17.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family BRAP2 PF07576.7 EPR78793.1 - 0.0068 15.9 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 Choline_kinase PF01633.15 EPR78793.1 - 0.034 13.7 0.7 0.059 12.9 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.11 EPR78793.1 - 0.04 13.9 0.0 0.19 11.7 0.0 2.0 1 1 1 2 2 2 0 ABC1 family TPR_2 PF07719.12 EPR78794.1 - 3.9e-16 57.5 3.7 0.095 12.6 0.1 8.1 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPR78794.1 - 4.6e-16 57.6 4.7 0.026 14.1 0.3 8.0 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EPR78794.1 - 1.8e-12 46.6 6.4 0.00015 21.3 0.0 6.3 4 3 2 6 6 6 3 TPR repeat TPR_12 PF13424.1 EPR78794.1 - 3.8e-10 39.5 3.2 0.039 13.8 0.0 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EPR78794.1 - 5.3e-09 36.0 2.3 5.3e-09 36.0 1.6 4.7 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EPR78794.1 - 8.9e-09 34.5 11.0 0.32 10.8 0.0 6.9 6 1 1 7 7 7 3 Tetratricopeptide repeat RPN7 PF10602.4 EPR78794.1 - 1.5e-06 27.7 6.1 0.0032 16.8 0.0 4.5 3 2 2 5 5 5 2 26S proteasome subunit RPN7 TPR_6 PF13174.1 EPR78794.1 - 1.5e-05 25.1 1.3 3.5 8.3 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPR78794.1 - 3.3e-05 24.1 0.0 4.2 8.2 0.0 5.4 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPR78794.1 - 0.00016 21.1 0.6 12 5.9 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPR78794.1 - 0.0013 18.5 3.9 0.28 11.1 0.5 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 EPR78794.1 - 0.0019 18.7 0.0 0.78 10.4 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPR78794.1 - 0.028 14.7 0.1 4.3 7.7 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPR78794.1 - 0.074 12.3 1.9 0.41 9.9 0.1 2.8 2 1 1 3 3 3 0 SHNi-TPR Acetyltransf_1 PF00583.19 EPR78795.1 - 1.2e-17 63.7 0.1 2e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPR78795.1 - 1.9e-17 63.2 0.8 2.9e-17 62.5 0.6 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPR78795.1 - 1.5e-10 41.1 0.6 1.8e-10 40.9 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPR78795.1 - 2.4e-10 40.5 0.0 3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPR78795.1 - 6.7e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPR78795.1 - 1.7e-06 27.8 0.1 2.8e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EPR78795.1 - 1.6e-05 25.0 0.1 2.1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPR78795.1 - 0.00065 19.6 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EPR78795.1 - 0.0025 17.3 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPR78795.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Hairy_orange PF07527.8 EPR78795.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Hairy Orange HHH_3 PF12836.2 EPR78795.1 - 0.28 11.1 1.6 10 6.1 0.2 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kinesin PF00225.18 EPR78796.1 - 1.1e-70 237.9 5.4 1.1e-70 237.9 3.7 2.6 2 1 0 2 2 2 1 Kinesin motor domain SAM_2 PF07647.12 EPR78796.1 - 0.00019 21.2 0.2 0.00039 20.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) T2SE PF00437.15 EPR78796.1 - 0.029 13.2 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein GATA PF00320.22 EPR78797.1 - 3.5e-09 35.8 2.3 8.9e-09 34.5 1.6 1.7 1 0 0 1 1 1 1 GATA zinc finger Fork_head PF00250.13 EPR78798.1 - 1.7e-18 66.4 1.6 1.7e-18 66.4 1.1 2.3 3 0 0 3 3 3 1 Fork head domain SAND PF01342.16 EPR78798.1 - 0.0019 17.8 2.5 0.37 10.5 1.0 3.2 2 2 0 2 2 2 2 SAND domain IRF PF00605.12 EPR78798.1 - 0.083 12.6 2.9 0.29 10.9 0.0 2.8 2 1 1 3 3 3 0 Interferon regulatory factor transcription factor Lipoprotein_Ltp PF07553.6 EPR78798.1 - 5.6 6.9 9.7 3.1 7.7 0.2 3.4 2 1 1 3 3 3 0 Host cell surface-exposed lipoprotein LRR_8 PF13855.1 EPR78799.1 - 9.6e-19 66.9 38.3 8.3e-07 28.6 2.3 7.9 7 1 1 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 EPR78799.1 - 4e-18 64.6 44.6 3.4e-08 32.9 3.7 9.0 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR78799.1 - 7e-08 31.4 26.6 0.22 11.6 0.7 10.1 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR78799.1 - 0.0023 17.8 18.4 3.1 8.4 0.2 10.0 12 0 0 12 12 12 1 Leucine rich repeat DEAD PF00270.24 EPR78800.1 - 2.7e-17 62.7 0.0 1.5e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EPR78800.1 - 1.8e-08 34.4 0.0 1.8e-08 34.4 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPR78800.1 - 2.6e-08 33.6 0.0 1.8e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FAINT PF04385.10 EPR78802.1 - 0.0023 17.7 2.8 0.0037 17.0 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function, DUF529 KaiC PF06745.8 EPR78802.1 - 0.0033 16.5 0.4 0.0037 16.4 0.3 1.1 1 0 0 1 1 1 1 KaiC DUF835 PF05763.7 EPR78802.1 - 0.048 13.2 1.4 0.057 12.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF835) DNA_pol_E_B PF04042.11 EPR78803.1 - 3.9e-24 85.0 0.5 6.1e-24 84.4 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 EPR78803.1 - 0.006 16.4 0.0 0.028 14.2 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain GTP_EFTU PF00009.22 EPR78804.1 - 1.3e-36 125.8 0.8 3.1e-36 124.5 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EPR78804.1 - 0.15 11.7 1.9 4.8 6.8 0.1 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Aldo_ket_red PF00248.16 EPR78805.1 - 6.2e-59 199.1 0.1 7.5e-59 198.8 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 EPR78808.1 - 6.2e-48 162.3 0.1 2.3e-47 160.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPR78808.1 - 1.4e-08 34.5 0.1 4.4e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPR78808.1 - 3.3e-08 33.6 0.0 9e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 EPR78808.1 - 6.2e-08 32.5 0.3 0.00021 21.0 0.0 3.5 3 0 0 3 3 3 1 NTPase AAA_16 PF13191.1 EPR78808.1 - 1.8e-07 31.3 0.1 2.8e-05 24.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPR78808.1 - 2.3e-07 31.0 0.6 3.2e-05 24.0 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPR78808.1 - 2.9e-06 27.1 0.1 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EPR78808.1 - 1.2e-05 24.4 0.0 2.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPR78808.1 - 0.00015 22.5 0.0 0.00046 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPR78808.1 - 0.00016 20.8 0.0 0.00034 19.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EPR78808.1 - 0.00033 20.7 0.0 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EPR78808.1 - 0.00077 19.1 0.2 0.002 17.8 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EPR78808.1 - 0.0011 17.7 0.1 0.0085 14.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus Arch_ATPase PF01637.13 EPR78808.1 - 0.0023 17.6 1.6 0.081 12.6 0.1 2.8 2 1 1 3 3 3 1 Archaeal ATPase UPF0079 PF02367.12 EPR78808.1 - 0.0025 17.4 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EPR78808.1 - 0.0029 17.5 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EPR78808.1 - 0.0037 16.7 0.4 0.078 12.4 0.0 2.8 3 1 0 3 3 2 1 Sigma-54 interaction domain NACHT PF05729.7 EPR78808.1 - 0.0049 16.5 0.4 0.23 11.1 0.0 2.4 1 1 1 2 2 2 1 NACHT domain AAA_33 PF13671.1 EPR78808.1 - 0.0052 16.6 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPR78808.1 - 0.0058 16.0 0.9 0.3 10.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EPR78808.1 - 0.0063 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPR78808.1 - 0.0073 15.9 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPR78808.1 - 0.009 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EPR78808.1 - 0.011 15.2 0.1 0.029 13.7 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EPR78808.1 - 0.011 16.0 0.0 0.041 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EPR78808.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EPR78808.1 - 0.021 13.9 2.5 0.36 9.9 0.0 2.7 2 1 1 3 3 3 0 KaiC Bac_DnaA PF00308.13 EPR78808.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Mg_chelatase PF01078.16 EPR78808.1 - 0.029 13.5 0.0 0.072 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EPR78808.1 - 0.068 13.2 0.0 0.47 10.5 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EPR78808.1 - 0.074 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPR78808.1 - 0.075 11.8 0.2 0.36 9.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 EPR78808.1 - 0.092 13.0 0.0 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 EPR78808.1 - 0.13 12.0 0.4 7.5 6.4 0.0 3.0 3 1 0 3 3 3 0 Shikimate kinase Med27 PF11571.3 EPR78811.1 - 0.018 15.1 2.3 0.019 15.0 1.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 27 zf-C3HC4 PF00097.20 EPR78811.1 - 0.25 11.0 2.6 0.67 9.6 1.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec62 PF03839.11 EPR78812.1 - 2e-28 99.3 2.7 2.3e-28 99.1 1.9 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF999 PF06198.6 EPR78812.1 - 0.083 12.6 1.8 0.12 12.1 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF999) Sed5p PF11416.3 EPR78812.1 - 0.13 11.6 0.3 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Integral membrane protein Sed5p DUF3796 PF12676.2 EPR78812.1 - 4.6 7.4 7.9 7.2 6.8 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) MS_channel PF00924.13 EPR78813.1 - 4.5e-11 42.4 0.3 4.9e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel Polysacc_deac_1 PF01522.16 EPR78814.1 - 4.9e-08 32.6 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_108 PF05838.7 EPR78814.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 108 SNF2_N PF00176.18 EPR78816.1 - 1.1e-31 109.8 9.3 3.8e-31 108.0 6.4 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPR78816.1 - 7.4e-10 38.5 0.0 2.6e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR78816.1 - 2.4e-07 30.7 5.0 4.4e-06 26.6 1.9 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPR78816.1 - 7.3e-06 25.5 0.0 0.15 11.5 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EPR78818.1 - 1.6e-14 53.4 12.3 2.8e-14 52.6 3.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPR78818.1 - 5e-10 38.8 9.7 2.5e-07 30.2 2.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR78818.1 - 5.2e-08 32.7 17.4 3.8e-07 30.0 4.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPR78818.1 - 3.3e-07 30.3 5.2 3.3e-07 30.3 3.6 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPR78818.1 - 2.2e-06 27.2 6.0 2.2e-06 27.2 4.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPR78818.1 - 2.8e-06 26.8 6.4 2.8e-06 26.8 4.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EPR78818.1 - 9e-06 25.5 3.2 9e-06 25.5 2.2 2.5 2 0 0 2 2 2 1 zinc-finger zf-Apc11 PF12861.2 EPR78818.1 - 0.0033 17.2 3.5 0.0033 17.2 2.4 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger NdhM PF10664.4 EPR78818.1 - 0.02 14.8 2.5 0.76 9.7 0.0 2.3 1 1 1 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M NSP13 PF06460.7 EPR78818.1 - 0.05 12.4 1.5 0.082 11.7 0.0 1.8 2 0 0 2 2 2 0 Coronavirus NSP13 DUF775 PF05603.7 EPR78818.1 - 0.067 12.6 0.8 0.089 12.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) zf-met2 PF12907.2 EPR78818.1 - 0.26 11.2 3.7 1.7 8.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-binding DNA_ligase_ZBD PF03119.11 EPR78818.1 - 0.47 10.1 3.1 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Nse PF11789.3 EPR78818.1 - 2.4 7.7 11.8 0.27 10.7 1.4 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 EPR78818.1 - 7.4 6.1 8.3 8.3 5.9 0.2 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif Brix PF04427.13 EPR78819.1 - 3.1e-09 36.7 0.3 3.3e-09 36.6 0.2 1.1 1 0 0 1 1 1 1 Brix domain PS_Dcarbxylase PF02666.10 EPR78821.1 - 9.3e-45 152.4 0.3 1.5e-44 151.7 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2905 PF11146.3 EPR78821.1 - 0.12 12.3 0.3 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) DnaJ PF00226.26 EPR78822.1 - 5.4e-07 29.2 0.2 2e-06 27.4 0.1 2.1 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L18p PF00861.17 EPR78824.1 - 1.6e-33 115.4 0.4 3e-33 114.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPR78824.1 - 3.2e-24 85.2 11.8 3.2e-24 85.2 8.2 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Pox_P35 PF03213.9 EPR78824.1 - 0.066 12.2 2.4 0.1 11.5 1.6 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein TaqI_C PF12950.2 EPR78824.1 - 0.18 11.5 4.7 0.79 9.4 1.6 2.4 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Rer1 PF03248.8 EPR78825.1 - 2.8e-44 150.8 12.6 3e-44 150.6 8.8 1.0 1 0 0 1 1 1 1 Rer1 family RNA_pol_Rpb4 PF03874.11 EPR78826.1 - 1.3e-16 60.6 0.0 1.6e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 SET_assoc PF11767.3 EPR78826.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF4049 PF13258.1 EPR78827.1 - 0.0037 16.2 1.0 0.0037 16.2 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4049) LUC7 PF03194.10 EPR78827.1 - 0.031 13.8 3.1 0.036 13.5 2.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus HEAT_2 PF13646.1 EPR78828.1 - 1.6e-05 25.0 0.1 0.003 17.8 0.0 3.3 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 EPR78828.1 - 0.00035 20.3 0.0 15 5.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat C1_4 PF07975.7 EPR78829.1 - 1.3e-05 25.0 19.6 1.3e-05 25.0 13.6 3.1 1 1 1 2 2 2 1 TFIIH C1-like domain zf-C3HC4_3 PF13920.1 EPR78829.1 - 0.0039 16.8 10.0 0.0039 16.8 6.9 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UPF0547 PF10571.4 EPR78829.1 - 0.026 14.1 1.6 0.026 14.1 1.1 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DZR PF12773.2 EPR78829.1 - 0.029 14.1 24.3 0.39 10.5 2.4 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 EPR78829.1 - 0.035 14.0 3.1 0.035 14.0 2.2 3.7 3 1 1 4 4 4 0 zinc-finger zf-RING_2 PF13639.1 EPR78829.1 - 0.91 9.4 23.9 0.98 9.3 7.4 3.4 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.1 EPR78829.1 - 1.4 9.0 29.9 0.13 12.2 10.4 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1g PF09334.6 EPR78829.1 - 3.3 6.2 5.9 0.69 8.5 1.5 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (M) zf-UBP PF02148.14 EPR78830.1 - 5.5e-12 45.6 15.2 5.5e-12 45.6 10.6 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 EPR78830.1 - 8.8e-08 31.5 5.9 8.8e-08 31.5 4.1 3.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Med26 PF08711.6 EPR78830.1 - 0.56 9.7 3.8 0.27 10.7 0.2 2.3 2 0 0 2 2 2 0 TFIIS helical bundle-like domain Latarcin PF10279.4 EPR78831.1 - 0.017 15.2 0.2 0.033 14.3 0.1 1.5 1 1 0 1 1 1 0 Latarcin precursor DUF1788 PF08747.6 EPR78831.1 - 0.76 9.6 4.2 0.76 9.6 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) PTPlike_phytase PF14566.1 EPR78832.1 - 0.0028 17.7 8.1 0.083 12.9 0.6 2.3 2 0 0 2 2 2 2 Inositol hexakisphosphate DUF1343 PF07075.6 EPR78832.1 - 2.2 7.0 7.4 0.15 10.9 1.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1343) IP_trans PF02121.13 EPR78833.1 - 8.2e-45 152.9 2.6 1e-44 152.6 1.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein NAD_Gly3P_dh_N PF01210.18 EPR78834.1 - 2.3e-29 102.1 0.0 4.6e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPR78834.1 - 1.7e-05 24.6 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.11 EPR78834.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EPR78834.1 - 0.058 13.8 0.2 0.87 10.0 0.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FliG_N PF14842.1 EPR78835.1 - 0.3 11.2 2.8 0.37 10.9 0.4 2.2 2 1 0 2 2 2 0 FliG N-terminal domain ATP-synt_A PF00119.15 EPR78835.1 - 0.51 9.7 3.7 0.32 10.4 0.8 1.8 1 1 1 2 2 2 0 ATP synthase A chain TBPIP PF07106.8 EPR78835.1 - 2.1 7.8 19.4 0.49 9.9 6.0 3.0 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Occludin_ELL PF07303.8 EPR78835.1 - 8.4 7.1 12.5 2.5 8.8 4.7 2.5 2 1 0 2 2 2 0 Occludin homology domain DUF2764 PF10962.3 EPR78836.1 - 0.02 14.1 2.5 0.023 13.9 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Imm39 PF15600.1 EPR78836.1 - 0.031 14.1 1.4 0.038 13.8 1.0 1.3 1 1 0 1 1 1 0 Immunity protein 39 RBD-FIP PF09457.5 EPR78836.1 - 0.16 11.8 1.6 0.25 11.1 0.3 1.9 2 0 0 2 2 2 0 FIP domain Lectin_leg-like PF03388.8 EPR78839.1 - 1.8e-12 46.8 0.7 2.2e-12 46.6 0.5 1.1 1 0 0 1 1 1 1 Legume-like lectin family WD40 PF00400.27 EPR78840.1 - 1.8e-35 119.5 14.5 2.5e-09 36.6 1.7 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPR78840.1 - 3.6e-05 23.4 7.6 0.21 11.3 0.2 4.3 2 2 2 4 4 4 4 Ciliary BBSome complex subunit 2, middle region NLE PF08154.7 EPR78840.1 - 0.0054 16.7 0.4 0.017 15.1 0.3 1.9 1 1 0 1 1 1 1 NLE (NUC135) domain X PF00739.14 EPR78840.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Trans-activation protein X PQQ_3 PF13570.1 EPR78840.1 - 0.15 12.3 0.2 29 5.1 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain OGG_N PF07934.7 EPR78843.1 - 8.1e-15 54.8 1.3 1.6e-14 53.8 0.1 2.0 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EPR78843.1 - 1.4e-11 44.6 0.0 3.7e-11 43.2 0.0 1.8 3 0 0 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein AF0941-like PF14591.1 EPR78843.1 - 0.032 14.2 0.4 0.032 14.2 0.3 2.3 2 1 0 2 2 2 0 AF0941-like HHH PF00633.18 EPR78843.1 - 0.06 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glyco_hydro_108 PF05838.7 EPR78843.1 - 0.095 12.8 0.1 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase 108 DUF4354 PF14263.1 EPR78844.1 - 1 9.0 4.7 2 8.1 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4354) SecE PF00584.15 EPR78845.1 - 6.1e-08 32.1 0.0 7.1e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Hira PF07569.6 EPR78846.1 - 0.0036 16.5 5.6 0.011 14.9 3.9 2.0 1 1 0 1 1 1 1 TUP1-like enhancer of split UBA_3 PF09288.5 EPR78847.1 - 0.077 12.6 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF1242 PF06842.7 EPR78848.1 - 1e-10 40.9 1.4 1.5e-10 40.3 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) SMC_N PF02463.14 EPR78851.1 - 4.9e-42 143.6 95.4 1.7e-40 138.5 66.1 4.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPR78851.1 - 1.9e-23 82.7 0.5 4.6e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EPR78851.1 - 1.3e-13 51.7 15.3 1.3e-13 51.7 10.6 7.2 2 2 3 5 5 5 2 AAA domain AAA_21 PF13304.1 EPR78851.1 - 1.3e-07 31.8 24.0 1.3e-07 31.8 16.6 5.7 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EPR78851.1 - 2.6e-06 26.8 0.0 5.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain WYL PF13280.1 EPR78852.1 - 0.076 12.8 0.3 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 WYL domain WD40 PF00400.27 EPR78853.1 - 1.1e-06 28.2 0.0 0.06 13.2 0.0 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EPR78853.1 - 0.014 15.6 0.1 0.067 13.4 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain HtrL_YibB PF09612.5 EPR78855.1 - 0.14 11.3 6.9 0.31 10.2 2.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (HtrL_YibB) Op_neuropeptide PF08035.6 EPR78856.1 - 0.14 11.7 3.2 0.8 9.3 0.1 2.8 2 0 0 2 2 2 0 Opioids neuropeptide Carboxyl_trans PF01039.17 EPR78857.1 - 6.6e-67 225.9 0.0 1.9e-64 217.8 0.0 2.1 1 1 0 1 1 1 1 Carboxyl transferase domain RNA_pol_Rpb6 PF01192.17 EPR78858.1 - 1.7e-21 75.7 0.1 2.1e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 tRNA-synt_1c PF00749.16 EPR78859.1 - 1.6e-88 296.4 1.1 1.6e-88 296.4 0.8 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPR78859.1 - 5.8e-18 65.1 1.8 5.8e-18 65.1 1.2 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain ATP_synt_H PF05493.8 EPR78860.1 - 8.5e-09 35.3 1.1 1.1e-08 35.0 0.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DUF4064 PF13273.1 EPR78860.1 - 0.00052 20.0 6.9 0.085 12.9 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) YibE_F PF07907.6 EPR78860.1 - 0.0011 18.1 2.0 0.0012 18.0 1.4 1.0 1 0 0 1 1 1 1 YibE/F-like protein Colicin_V PF02674.11 EPR78860.1 - 0.0047 16.7 0.4 0.0049 16.7 0.3 1.1 1 0 0 1 1 1 1 Colicin V production protein ATP_synt_I PF03899.10 EPR78860.1 - 0.0097 16.0 1.5 0.011 15.8 1.0 1.2 1 0 0 1 1 1 1 ATP synthase I chain DUF1772 PF08592.6 EPR78860.1 - 0.015 15.0 0.2 0.019 14.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) 7TM_GPCR_Srd PF10317.4 EPR78860.1 - 0.015 14.2 0.8 0.016 14.2 0.5 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF4131 PF13567.1 EPR78860.1 - 0.016 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) O-antigen_lig PF13425.1 EPR78860.1 - 0.017 15.1 0.6 0.02 14.8 0.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF3112 PF11309.3 EPR78860.1 - 0.034 13.9 1.8 0.037 13.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) OPT PF03169.10 EPR78860.1 - 0.035 12.5 1.0 0.037 12.4 0.0 1.4 1 1 0 1 1 1 0 OPT oligopeptide transporter protein AA_permease_2 PF13520.1 EPR78860.1 - 0.066 11.7 2.8 0.071 11.6 1.9 1.0 1 0 0 1 1 1 0 Amino acid permease OppC_N PF12911.2 EPR78860.1 - 0.099 12.0 4.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2975 PF11188.3 EPR78860.1 - 0.24 11.1 8.1 0.3 10.8 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) 7TMR-DISM_7TM PF07695.6 EPR78860.1 - 0.26 10.9 7.3 0.3 10.7 5.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF2254 PF10011.4 EPR78860.1 - 0.3 9.5 1.8 0.4 9.0 1.2 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF1212 PF06738.7 EPR78860.1 - 0.36 10.2 2.7 0.48 9.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF4229 PF14012.1 EPR78860.1 - 0.58 10.0 6.0 0.77 9.7 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Glucos_trans_II PF14264.1 EPR78860.1 - 0.61 9.0 7.9 0.74 8.7 5.5 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF1003 PF06210.6 EPR78860.1 - 0.77 9.7 3.0 0.92 9.4 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) DUF4013 PF13197.1 EPR78860.1 - 0.78 9.0 9.2 0.91 8.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF4446 PF14584.1 EPR78860.1 - 0.81 9.5 4.5 7.9 6.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Peptidase_A24 PF01478.13 EPR78860.1 - 0.92 9.7 4.1 1.3 9.2 2.9 1.3 1 0 0 1 1 1 0 Type IV leader peptidase family DUF3792 PF12670.2 EPR78860.1 - 1.2 9.0 7.4 1.4 8.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) VKOR PF07884.9 EPR78860.1 - 1.2 9.0 5.6 1.5 8.6 3.8 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family MFS_2 PF13347.1 EPR78860.1 - 1.2 7.4 6.0 1.5 7.1 4.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Yip1 PF04893.12 EPR78860.1 - 1.8 8.0 7.8 2.2 7.7 5.4 1.1 1 0 0 1 1 1 0 Yip1 domain DUF2681 PF10883.3 EPR78860.1 - 2.3 8.4 5.7 32 4.8 4.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) DUF805 PF05656.9 EPR78860.1 - 3.6 7.4 7.2 18 5.1 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) ABC2_membrane PF01061.19 EPR78860.1 - 4 6.5 8.6 4.8 6.2 5.9 1.0 1 0 0 1 1 1 0 ABC-2 type transporter Tetraspannin PF00335.15 EPR78860.1 - 6.6 5.9 6.6 9.3 5.4 4.6 1.3 1 1 0 1 1 1 0 Tetraspanin family EXS PF03124.9 EPR78861.1 - 6.4e-31 107.6 35.5 6.4e-31 107.6 24.6 2.6 3 0 0 3 3 3 1 EXS family DUF2439 PF10382.4 EPR78863.1 - 9.7e-06 25.7 6.2 9.7e-06 25.7 4.3 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2439) Gp_dh_C PF02800.15 EPR78864.1 - 4.3e-56 188.7 0.3 6.3e-56 188.1 0.2 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPR78864.1 - 1.4e-36 125.7 0.1 2.6e-36 124.8 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPR78864.1 - 0.0089 15.1 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPR78864.1 - 0.099 12.6 0.2 3.1 7.8 0.0 2.3 1 1 0 2 2 2 0 TrkA-N domain DUF2414 PF10309.4 EPR78864.1 - 0.099 12.3 3.3 1.7 8.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Peptidase_C48 PF02902.14 EPR78865.1 - 2.7e-21 76.1 9.8 4.3e-21 75.5 6.8 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DnaJ-X PF14308.1 EPR78866.1 - 0.014 14.6 1.7 0.016 14.4 1.2 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing Med7 PF05983.6 EPR78866.1 - 0.034 13.9 6.2 0.032 14.0 3.9 1.3 1 1 0 1 1 1 0 MED7 protein DALR_1 PF05746.10 EPR78866.1 - 0.1 12.5 0.6 0.13 12.2 0.4 1.1 1 0 0 1 1 1 0 DALR anticodon binding domain Sec1 PF00995.18 EPR78870.1 - 6.5e-42 143.9 34.2 1.8e-40 139.1 23.7 2.4 1 1 0 1 1 1 1 Sec1 family NOA36 PF06524.7 EPR78870.1 - 7.3 5.7 0.0 7.3 5.7 0.0 2.7 3 0 0 3 3 3 0 NOA36 protein Pkinase PF00069.20 EPR78871.1 - 1.9e-34 118.9 0.1 2.3e-34 118.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR78871.1 - 2.9e-12 46.2 0.0 4.1e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPR78871.1 - 8.6e-07 28.9 0.0 0.0059 16.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPR78871.1 - 0.0023 17.0 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPR78871.1 - 0.034 13.4 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.19 EPR78872.1 - 3.6e-127 424.9 18.1 4.1e-127 424.7 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4238 PF14022.1 EPR78873.1 - 0.08 12.2 6.1 0.17 11.1 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) Vmethyltransf_C PF08456.5 EPR78873.1 - 0.086 12.2 4.8 0.082 12.3 0.3 2.1 2 0 0 2 2 2 0 Viral methyltransferase C-terminal UPF0061 PF02696.9 EPR78873.1 - 0.098 10.9 0.9 0.15 10.3 0.6 1.4 1 1 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Mit_KHE1 PF10173.4 EPR78874.1 - 0.044 13.6 1.1 0.49 10.2 0.1 2.5 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related Chloroplast_duf PF14476.1 EPR78874.1 - 0.061 12.1 0.0 0.085 11.6 0.0 1.1 1 0 0 1 1 1 0 Petal formation-expressed DNA_ligase_A_N PF04675.9 EPR78876.1 - 0.1 12.4 0.2 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 DNA ligase N terminus GET2 PF08690.5 EPR78876.1 - 0.26 10.5 9.6 0.28 10.3 6.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 WD40 PF00400.27 EPR78877.1 - 1.9e-31 106.7 7.1 4.8e-08 32.5 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat LisH PF08513.6 EPR78877.1 - 1.8e-07 30.6 0.9 3.8e-07 29.6 0.7 1.6 1 0 0 1 1 1 1 LisH ExbD PF02472.11 EPR78877.1 - 4.7 7.2 7.2 1.6 8.7 0.6 2.8 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Slx4 PF09494.5 EPR78878.1 - 0.085 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Slx4 endonuclease V-ATPase_C PF03223.10 EPR78879.1 - 3.3e-21 75.6 16.8 4.5e-21 75.1 11.6 1.1 1 0 0 1 1 1 1 V-ATPase subunit C Mor PF08765.6 EPR78880.1 - 0.019 14.7 0.6 0.053 13.3 0.0 2.0 2 0 0 2 2 2 0 Mor transcription activator family IMS PF00817.15 EPR78881.1 - 1.1e-38 132.3 0.0 1.8e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPR78881.1 - 5.1e-07 29.6 0.3 2.1e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPR78881.1 - 5.6e-05 22.9 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.6 EPR78881.1 - 0.15 11.8 0.0 0.55 10.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Aminotran_1_2 PF00155.16 EPR78882.1 - 1.1e-46 159.4 0.0 1.4e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPR78882.1 - 0.00022 20.4 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Metalloenzyme PF01676.13 EPR78883.1 - 1.3e-68 231.0 1.0 1.6e-68 230.8 0.7 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EPR78883.1 - 3.3e-54 183.5 4.7 5.2e-54 182.9 3.3 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EPR78883.1 - 6.2e-08 32.3 0.1 1.1e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPR78883.1 - 2.8e-05 23.4 0.0 4.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.7 EPR78883.1 - 0.021 14.4 0.0 0.19 11.3 0.0 2.3 2 1 0 2 2 2 0 PglZ domain UBA PF00627.26 EPR78885.1 - 6.1e-05 22.7 1.1 0.00017 21.3 0.0 2.2 3 0 0 3 3 3 1 UBA/TS-N domain AHS1 PF02682.11 EPR78885.1 - 0.00056 19.4 0.3 0.00064 19.2 0.2 1.1 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Med6 PF04934.9 EPR78885.1 - 0.0022 17.5 2.4 0.0038 16.7 1.7 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component SPT6_acidic PF14632.1 EPR78885.1 - 0.03 14.4 5.7 0.054 13.6 4.0 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 MCPVI PF02993.9 EPR78885.1 - 0.036 14.2 1.7 0.04 14.0 1.2 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Ribosomal_S13 PF00416.17 EPR78885.1 - 0.1 13.0 0.1 0.1 13.0 0.1 3.0 1 1 2 3 3 3 0 Ribosomal protein S13/S18 NAC PF01849.13 EPR78885.1 - 0.16 11.5 0.1 0.16 11.5 0.1 2.4 3 1 0 3 3 3 0 NAC domain Fib_alpha PF08702.5 EPR78885.1 - 9.8 6.2 9.7 3.8 7.6 4.6 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PPTA PF01239.17 EPR78886.1 - 1.9e-08 33.3 15.5 4.7e-06 25.7 1.0 4.2 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Herpes_UL69 PF05459.7 EPR78887.1 - 0.0016 17.6 0.7 0.23 10.5 0.0 2.2 2 0 0 2 2 2 2 Herpesvirus transcriptional regulator family ATP-synt_B PF00430.13 EPR78887.1 - 0.099 12.4 6.5 0.43 10.3 3.0 2.4 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DP PF08781.5 EPR78888.1 - 1.5e-10 40.9 2.2 2.2e-10 40.3 1.5 1.2 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.15 EPR78888.1 - 1.8e-09 37.0 2.1 2.8e-09 36.4 1.2 1.6 1 1 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain MSA-2c PF12238.3 EPR78888.1 - 1.3 8.6 4.5 0.35 10.5 0.8 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c SUI1 PF01253.17 EPR78889.1 - 5.7e-17 61.2 0.7 6.7e-17 61.0 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 MgtE_N PF03448.12 EPR78889.1 - 0.1 12.9 0.1 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Ribosomal_S19e PF01090.14 EPR78890.1 - 1e-27 96.3 0.1 1.2e-27 96.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e DUF4285 PF14113.1 EPR78890.1 - 0.0089 16.0 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4285) Rrf2 PF02082.15 EPR78890.1 - 0.042 13.9 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.2 EPR78890.1 - 0.13 11.9 0.0 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 MarR family Nop14 PF04147.7 EPR78891.1 - 0.37 8.6 3.5 0.4 8.5 2.4 1.0 1 0 0 1 1 1 0 Nop14-like family Thymidylat_synt PF00303.14 EPR78892.1 - 2.5e-107 357.8 0.0 2.8e-107 357.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 EPR78893.1 - 3.2e-19 69.0 1.0 4.3e-19 68.6 0.7 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase DUF4563 PF15124.1 EPR78893.1 - 0.013 15.1 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4563) DUF3760 PF12586.3 EPR78893.1 - 0.14 11.9 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) AAA_22 PF13401.1 EPR78895.1 - 2.6e-06 27.5 0.3 1.2e-05 25.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPR78895.1 - 1.5e-05 24.8 1.2 1.5e-05 24.8 0.8 3.8 3 2 1 4 4 3 1 AAA domain AAA_17 PF13207.1 EPR78895.1 - 1.7e-05 25.6 11.8 3.2e-05 24.7 0.8 3.4 2 2 1 3 3 3 1 AAA domain AAA PF00004.24 EPR78895.1 - 0.0003 21.0 0.0 0.00097 19.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPR78895.1 - 0.00031 21.0 2.2 0.00031 21.0 1.5 4.6 2 2 0 2 2 1 1 AAA domain NB-ARC PF00931.17 EPR78895.1 - 0.00035 19.5 0.1 0.00035 19.5 0.1 2.3 2 1 1 3 3 3 1 NB-ARC domain AAA_19 PF13245.1 EPR78895.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EPR78895.1 - 0.0022 17.6 0.3 0.0022 17.6 0.2 2.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPR78895.1 - 0.0028 17.2 0.0 0.0028 17.2 0.0 2.5 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 EPR78895.1 - 0.0036 16.8 0.0 0.069 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EPR78895.1 - 0.0037 17.1 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPR78895.1 - 0.0047 16.9 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 EPR78895.1 - 0.0072 15.8 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EPR78895.1 - 0.0087 16.3 0.1 0.0087 16.3 0.1 2.8 2 1 0 2 2 1 1 ABC transporter cobW PF02492.14 EPR78895.1 - 0.0094 15.4 0.0 0.025 14.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EPR78895.1 - 0.011 14.8 0.0 0.029 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EPR78895.1 - 0.017 14.0 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EPR78895.1 - 0.038 14.1 7.6 0.045 13.9 0.1 2.9 2 0 0 2 2 2 0 RNA helicase RNA_bind_2 PF10133.4 EPR78895.1 - 0.046 13.7 0.7 0.046 13.7 0.5 2.6 2 1 0 2 2 2 0 Predicted RNA-binding protein AAA_28 PF13521.1 EPR78895.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EPR78895.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.21 EPR78896.1 - 1.6e-24 86.2 0.7 2e-24 85.9 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4041 PF13250.1 EPR78896.1 - 0.033 13.7 0.4 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) WAPL PF07814.8 EPR78896.1 - 0.12 11.0 0.2 0.16 10.6 0.1 1.4 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin PRK PF00485.13 EPR78897.1 - 0.018 14.5 0.2 0.14 11.6 0.1 2.2 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNase_H_2 PF13482.1 EPR78897.1 - 0.057 13.2 4.0 0.035 13.9 0.6 2.2 2 1 1 3 3 3 0 RNase_H superfamily ArsA_ATPase PF02374.10 EPR78898.1 - 8e-09 34.9 0.1 1.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EPR78898.1 - 4.2e-08 32.8 0.2 9e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.4 EPR78898.1 - 1.6e-07 31.1 1.1 4.7e-07 29.5 0.7 1.9 1 0 0 1 1 1 1 ParA/MinD ATPase like AAA_31 PF13614.1 EPR78898.1 - 2.5e-07 30.7 0.5 5.6e-07 29.6 0.1 1.8 2 1 0 2 2 2 1 AAA domain YhjQ PF06564.7 EPR78898.1 - 0.0054 16.1 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 YhjQ protein MipZ PF09140.6 EPR78898.1 - 0.012 14.7 0.1 0.034 13.2 0.0 1.7 1 1 1 2 2 2 0 ATPase MipZ AAA_18 PF13238.1 EPR78898.1 - 0.012 15.8 5.5 0.017 15.4 2.1 2.5 1 1 1 2 2 2 0 AAA domain Desulfoferrod_N PF06397.7 EPR78898.1 - 0.019 14.3 0.3 0.035 13.4 0.2 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain ABC_tran PF00005.22 EPR78898.1 - 0.058 13.6 1.9 0.091 13.0 1.3 1.5 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EPR78898.1 - 0.36 11.6 2.8 4.1 8.2 1.9 2.7 1 1 0 1 1 1 0 AAA domain HlyD_3 PF13437.1 EPR78899.1 - 0.042 14.1 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein TPR_1 PF00515.23 EPR78900.1 - 2.4e-08 33.2 25.5 0.0065 16.0 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EPR78900.1 - 2e-07 31.0 18.7 0.0095 16.0 0.1 5.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EPR78900.1 - 2.1e-07 30.3 23.1 0.082 12.8 1.7 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPR78900.1 - 1.3e-06 28.1 16.1 0.07 13.0 0.6 6.5 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPR78900.1 - 5.8e-06 26.5 0.5 0.12 12.6 0.0 5.6 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPR78900.1 - 1.1e-05 25.9 0.8 0.53 11.0 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPR78900.1 - 0.0049 16.4 19.6 4.5 6.9 0.2 6.8 4 2 1 5 5 5 3 TPR repeat TPR_6 PF13174.1 EPR78900.1 - 0.031 14.7 4.6 33 5.2 0.1 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPR78900.1 - 0.64 9.9 7.1 3.2 7.7 0.1 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat UDPG_MGDP_dh_C PF03720.10 EPR78901.1 - 0.045 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Peptidase_S49_N PF08496.5 EPR78902.1 - 0.043 13.6 0.2 0.043 13.6 0.1 6.1 3 2 2 5 5 5 0 Peptidase family S49 N-terminal S-AdoMet_synt_C PF02773.11 EPR78903.1 - 1.7e-67 225.4 0.0 2.7e-67 224.7 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EPR78903.1 - 2e-46 156.8 0.1 4.6e-46 155.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EPR78903.1 - 2.2e-34 117.6 0.3 2.2e-34 117.6 0.2 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.14 EPR78903.1 - 0.00042 18.9 1.6 0.098 11.1 0.2 2.2 2 0 0 2 2 2 2 S-adenosylmethionine synthetase (AdoMet synthetase) Zip PF02535.17 EPR78906.1 - 1.4e-37 129.4 0.8 1.9e-37 128.9 0.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UPF0560 PF10577.4 EPR78906.1 - 3 5.9 9.8 0.059 11.6 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Sod_Fe_C PF02777.13 EPR78908.1 - 2.1e-35 120.7 1.5 3.6e-35 120.0 0.7 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPR78908.1 - 6.9e-26 90.3 2.2 1.6e-25 89.1 1.5 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FoP_duplication PF13865.1 EPR78909.1 - 0.021 15.2 2.6 0.021 15.2 1.8 2.8 1 1 1 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PDGLE PF13190.1 EPR78910.1 - 0.095 12.3 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 PDGLE domain DUF3899 PF13038.1 EPR78910.1 - 0.14 12.2 3.0 0.66 10.1 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) PQQ_3 PF13570.1 EPR78911.1 - 0.016 15.4 0.1 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain LSM PF01423.17 EPR78912.1 - 1.3e-17 63.0 0.7 1.5e-17 62.8 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPR78912.1 - 3.5e-06 26.8 0.0 4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EPR78912.1 - 0.04 13.7 0.2 0.11 12.3 0.2 1.7 1 1 0 1 1 1 0 Scd6-like Sm domain AAA_5 PF07728.9 EPR78913.1 - 1.2e-13 50.9 0.0 6.5e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPR78913.1 - 3.9e-07 30.2 0.0 8.1e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPR78913.1 - 1.4e-06 28.5 0.0 4.3e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPR78913.1 - 9.3e-05 22.7 2.8 0.00012 22.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EPR78913.1 - 0.0001 21.8 0.0 0.00025 20.6 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPR78913.1 - 0.0019 18.2 0.0 0.0025 17.8 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EPR78913.1 - 0.0024 17.7 0.8 0.0024 17.7 0.6 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPR78913.1 - 0.0035 18.1 0.8 0.0045 17.8 0.0 1.7 2 1 0 2 2 1 1 AAA domain RNA_pol_Rpb1_2 PF00623.15 EPR78913.1 - 0.0044 16.9 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 Zeta_toxin PF06414.7 EPR78913.1 - 0.0046 16.0 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NTPase_1 PF03266.10 EPR78913.1 - 0.0079 15.9 0.0 0.01 15.5 0.0 1.3 1 1 0 1 1 1 1 NTPase KAP_NTPase PF07693.9 EPR78913.1 - 0.008 15.2 0.0 0.02 13.8 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain Viral_helicase1 PF01443.13 EPR78913.1 - 0.026 14.0 0.0 0.66 9.4 0.0 2.3 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Nop14 PF04147.7 EPR78913.1 - 0.034 12.0 0.0 0.05 11.5 0.0 1.2 1 0 0 1 1 1 0 Nop14-like family FANCI_S4 PF14678.1 EPR78913.1 - 0.047 12.8 1.4 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 FANCI solenoid 4 DUF258 PF03193.11 EPR78913.1 - 0.076 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPR78913.1 - 0.13 12.5 1.2 0.47 10.7 0.1 2.2 2 1 1 3 3 3 0 ABC transporter AAA_19 PF13245.1 EPR78913.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Ribul_P_3_epim PF00834.14 EPR78914.1 - 0.11 11.5 0.0 0.21 10.7 0.0 1.5 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family SpoU_sub_bind PF08032.7 EPR78914.1 - 0.62 10.2 3.8 14 5.9 0.1 2.2 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF3783 PF12646.2 EPR78914.1 - 2.3 8.0 5.4 0.73 9.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) dCMP_cyt_deam_1 PF00383.17 EPR78916.1 - 1.1e-20 73.1 0.8 1.4e-20 72.8 0.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FAM24 PF15193.1 EPR78916.1 - 0.13 12.4 2.7 0.13 12.4 0.8 1.7 1 1 0 1 1 1 0 FAM24 family Ribosomal_S3_C PF00189.15 EPR78917.1 - 4.3e-16 58.9 6.0 7.4e-16 58.1 1.9 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain TAP42 PF04177.7 EPR78918.1 - 0.0014 17.6 25.3 0.35 9.7 3.9 4.2 1 1 1 2 2 2 2 TAP42-like family DUF4477 PF14780.1 EPR78919.1 - 0.079 12.3 2.7 2.4 7.4 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Med31 PF05669.7 EPR78919.1 - 0.12 12.1 3.7 0.094 12.4 1.8 1.4 1 1 0 1 1 1 0 SOH1 DUF913 PF06025.7 EPR78920.1 - 7.5e-05 21.6 5.6 9.8e-05 21.2 3.9 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) ImcF-related_N PF14331.1 EPR78920.1 - 0.14 11.0 1.4 0.21 10.4 0.9 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain Chlamy_scaf PF09675.5 EPR78920.1 - 1.2 9.2 9.8 0.41 10.6 3.0 2.5 2 2 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Proteasome PF00227.21 EPR78924.1 - 6.2e-37 126.7 0.5 7e-37 126.5 0.4 1.0 1 0 0 1 1 1 1 Proteasome subunit AP_endonuc_2 PF01261.19 EPR78925.1 - 1e-23 83.7 0.3 6.4e-22 77.8 0.2 2.9 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel UPF0058 PF01893.11 EPR78925.1 - 0.17 11.9 1.4 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0058 WD40 PF00400.27 EPR78926.1 - 5e-21 73.7 3.9 0.0017 18.1 0.0 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat SPT16 PF08644.6 EPR78927.1 - 9.9e-27 93.6 3.6 9.9e-27 93.6 2.5 4.1 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EPR78927.1 - 3.4e-16 59.1 0.1 3.4e-16 59.1 0.1 3.3 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EPR78927.1 - 8.5e-13 48.1 2.9 8.5e-13 48.1 2.0 3.0 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EPR78927.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 tRNA-synt_1e PF01406.14 EPR78928.1 - 4e-110 367.6 5.1 4e-110 367.6 3.5 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EPR78928.1 - 1.8e-13 49.9 2.6 3e-07 29.4 0.3 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPR78928.1 - 6.5e-07 27.7 0.1 0.00016 19.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EPR78928.1 - 0.068 13.4 0.3 0.2 11.9 0.2 1.9 1 0 0 1 1 1 0 DALR domain RestrictionSfiI PF11487.3 EPR78930.1 - 0.063 12.4 0.5 0.13 11.4 0.1 1.6 1 1 1 2 2 2 0 Type II restriction enzyme SfiI YtxH PF12732.2 EPR78930.1 - 0.11 12.8 0.2 0.2 12.0 0.1 1.4 1 0 0 1 1 1 0 YtxH-like protein S-antigen PF05756.6 EPR78930.1 - 0.26 11.3 1.9 1.9 8.5 1.3 2.1 1 1 0 1 1 1 0 S-antigen protein PfkB PF00294.19 EPR78931.1 - 2.3e-17 63.0 0.0 3e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPR78931.1 - 0.00022 20.5 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase POT1 PF02765.12 EPR78932.1 - 9e-05 22.4 2.8 0.00021 21.2 0.8 2.5 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EPR78932.1 - 0.00074 19.3 0.1 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Peptidase_S76 PF13611.1 EPR78932.1 - 2.8 8.0 8.0 1.7 8.7 0.5 2.9 1 1 1 3 3 3 0 Serine peptidase of plant viral polyprotein, P1 Sld5 PF05916.6 EPR78933.1 - 6e-15 55.4 0.4 8.1e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 GINS complex protein BIR PF00653.16 EPR78935.1 - 2.9e-14 53.2 7.8 8.4e-13 48.5 2.2 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain SSrecog PF03531.9 EPR78936.1 - 8.4e-26 90.6 2.7 9e-25 87.2 1.9 2.4 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EPR78936.1 - 1e-17 63.8 4.2 2e-16 59.7 0.1 2.8 3 0 0 3 3 3 2 Histone chaperone Rttp106-like YcxB PF14317.1 EPR78936.1 - 0.017 14.3 1.1 0.97 8.7 0.0 3.4 3 0 0 3 3 3 0 YcxB-like protein Abhydrolase_5 PF12695.2 EPR78937.1 - 1.5e-09 37.7 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EPR78937.1 - 8e-07 28.9 0.1 0.00016 21.4 0.0 2.0 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EPR78937.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EPR78937.1 - 0.025 14.4 0.0 0.34 10.7 0.0 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPR78937.1 - 0.06 12.8 0.1 5.9 6.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold MCM PF00493.18 EPR78938.1 - 7.3e-98 327.4 0.3 1.1e-97 326.7 0.0 1.4 2 0 0 2 2 2 1 MCM2/3/5 family AAA_5 PF07728.9 EPR78938.1 - 2.3e-07 30.6 0.0 5.4e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPR78938.1 - 1.1e-06 27.9 0.2 0.011 14.9 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPR78938.1 - 0.00088 18.8 0.0 0.0043 16.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Far-17a_AIG1 PF04750.9 EPR78939.1 - 1.5e-22 79.7 12.5 1.9e-22 79.4 8.7 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Claudin_2 PF13903.1 EPR78939.1 - 0.047 13.3 2.8 1.4 8.5 1.4 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction PgaD PF13994.1 EPR78939.1 - 1.3 8.4 5.3 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 PgaD-like protein Spo7 PF03907.8 EPR78939.1 - 4.8 6.7 10.4 0.19 11.3 1.2 2.0 1 1 1 2 2 2 0 Spo7-like protein UCH PF00443.24 EPR78940.1 - 1.1e-09 37.8 1.9 2.1e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR78940.1 - 3.3e-06 26.7 5.3 0.0002 20.9 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_2 PF00152.15 EPR78941.1 - 1.5e-77 260.6 2.9 2e-77 260.2 2.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPR78941.1 - 7.1e-11 41.8 0.4 1.4e-10 40.8 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EPR78941.1 - 0.0018 18.0 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PhaP_Bmeg PF09602.5 EPR78941.1 - 0.014 15.2 1.2 1.7 8.4 0.2 2.8 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) tRNA-synt_2d PF01409.15 EPR78941.1 - 0.033 13.3 0.1 2.3 7.3 0.0 2.7 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EPR78942.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain CTP_transf_2 PF01467.21 EPR78943.1 - 0.055 13.5 0.2 0.15 12.1 0.4 1.7 2 0 0 2 2 2 0 Cytidylyltransferase Peptidase_M16 PF00675.15 EPR78946.1 - 4.2e-07 29.8 1.8 3.2e-06 26.9 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPR78946.1 - 0.00038 20.1 0.5 0.0011 18.6 0.4 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Chromate_transp PF02417.10 EPR78947.1 - 0.083 12.4 0.3 0.1 12.2 0.2 1.1 1 0 0 1 1 1 0 Chromate transporter 2TM PF13239.1 EPR78947.1 - 0.37 10.8 2.2 0.58 10.2 1.6 1.6 1 1 0 1 1 1 0 2TM domain DNA_topoisoIV PF00521.15 EPR78948.1 - 1.3e-118 396.5 3.2 1.3e-118 396.5 2.2 2.3 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EPR78948.1 - 4.7e-35 120.3 5.4 2.1e-34 118.2 3.8 2.2 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EPR78948.1 - 5.5e-14 51.9 0.0 3.1e-13 49.5 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EPR78948.1 - 2.9e-10 39.8 0.2 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1097 PF06496.6 EPR78950.1 - 0.014 15.2 2.9 0.014 15.2 2.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1097) DUF962 PF06127.6 EPR78950.1 - 0.039 13.8 0.6 3.1 7.7 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF962) BIV_Env PF05858.7 EPR78950.1 - 0.23 9.3 5.0 0.13 10.1 1.5 1.8 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) DUF3753 PF12575.3 EPR78950.1 - 1.1 9.0 5.0 3.3 7.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) DUF1129 PF06570.6 EPR78950.1 - 3.3 6.9 9.5 0.7 9.1 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF2157 PF09925.4 EPR78950.1 - 3.4 7.2 9.3 0.086 12.4 0.8 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) DUF3040 PF11239.3 EPR78950.1 - 4 7.5 15.6 3 7.9 2.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) RRM_1 PF00076.17 EPR78951.1 - 0.00012 21.6 2.6 0.0063 16.1 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EPR78951.1 - 0.00015 21.2 0.3 0.0046 16.5 0.0 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF1866) DUF3647 PF12363.3 EPR78951.1 - 0.028 14.5 6.2 0.044 13.8 0.3 2.7 2 1 0 3 3 3 0 Phage protein RRM_5 PF13893.1 EPR78951.1 - 0.044 13.6 5.0 1.4 8.8 0.2 3.3 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF87 PF01935.12 EPR78951.1 - 0.086 12.6 1.1 0.14 11.9 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 RRM_3 PF08777.6 EPR78951.1 - 0.096 12.5 4.3 0.045 13.6 1.2 1.8 2 0 0 2 2 2 0 RNA binding motif RRM_6 PF14259.1 EPR78951.1 - 0.2 11.6 1.8 3.4 7.7 0.2 2.7 1 1 2 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF310 PF03750.8 EPR78951.1 - 6.8 6.9 8.3 18 5.5 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF310) Flu_NS1 PF00600.14 EPR78952.1 - 0.29 10.2 2.9 0.28 10.2 1.3 1.5 1 1 0 1 1 1 0 Influenza non-structural protein (NS1) Ribosomal_L40e PF01020.12 EPR78953.1 - 7.9e-17 60.5 10.1 1.2e-16 60.0 7.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 EPR78953.1 - 2.4e-06 26.8 0.0 4.3e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family zf-DHHC PF01529.15 EPR78953.1 - 0.0036 16.7 0.4 0.0056 16.0 0.3 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rad60-SLD PF11976.3 EPR78953.1 - 0.0062 16.1 0.0 0.017 14.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PRK PF00485.13 EPR78954.1 - 1.6e-20 73.4 0.2 5.2e-19 68.5 0.1 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EPR78954.1 - 5.4e-07 30.4 0.1 1.3e-06 29.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR78954.1 - 1.8e-05 25.0 0.1 4.3e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EPR78954.1 - 0.00015 21.4 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EPR78954.1 - 0.00067 18.9 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EPR78954.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.1 EPR78954.1 - 0.0042 17.1 11.8 0.0042 17.1 8.2 1.5 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.15 EPR78954.1 - 0.0088 15.7 0.1 0.056 13.1 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase ATP-synt_ab PF00006.20 EPR78954.1 - 0.0088 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EPR78954.1 - 0.018 13.9 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.15 EPR78954.1 - 0.021 13.4 1.0 0.019 13.6 0.7 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 EPR78954.1 - 0.027 14.3 0.2 0.064 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EPR78954.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.1 EPR78954.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPR78954.1 - 0.092 12.6 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPR78954.1 - 0.1 12.0 0.1 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EPR78954.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.6 EPR78954.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.1 EPR78954.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain AAA_30 PF13604.1 EPR78954.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-CCCH PF00642.19 EPR78956.1 - 8.3e-08 31.7 32.0 7.4e-05 22.3 0.6 4.7 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ABC_trans_N PF14510.1 EPR78956.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal ATP-synt_C PF00137.16 EPR78957.1 - 2.3e-07 30.6 4.5 2.3e-07 30.6 3.1 2.2 2 0 0 2 2 2 1 ATP synthase subunit C DUF4536 PF15055.1 EPR78957.1 - 0.26 11.3 1.4 0.94 9.6 0.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) ATP-synt_C PF00137.16 EPR78958.1 - 3e-09 36.6 4.1 3e-09 36.6 2.8 2.5 2 1 0 2 2 2 1 ATP synthase subunit C Sigma_reg_N PF13800.1 EPR78959.1 - 0.033 14.2 3.7 0.033 14.2 2.6 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SP_C-Propep PF08999.5 EPR78959.1 - 0.26 10.8 1.2 0.35 10.3 0.9 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF3753 PF12575.3 EPR78959.1 - 0.38 10.5 3.9 0.95 9.3 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ETRAMP PF09716.5 EPR78959.1 - 8.8 6.3 8.0 28 4.7 5.5 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Chordopox_A33R PF05966.7 EPR78959.1 - 8.9 5.0 7.5 0.67 8.6 1.3 1.7 1 1 1 2 2 2 0 Chordopoxvirus A33R protein LSM PF01423.17 EPR78961.1 - 9.2e-07 28.3 1.3 1.2e-06 27.9 0.9 1.2 1 0 0 1 1 1 1 LSM domain LRR_4 PF12799.2 EPR78962.1 - 1.1e-36 123.8 142.5 1.9e-07 30.5 4.2 13.4 7 3 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78962.1 - 5e-28 96.6 113.1 2.4e-08 33.6 2.2 11.3 4 2 10 14 14 14 12 Leucine rich repeat LRR_1 PF00560.28 EPR78962.1 - 1.7e-18 63.8 106.5 0.1 12.7 0.2 20.3 18 1 2 20 20 20 12 Leucine Rich Repeat LRR_7 PF13504.1 EPR78962.1 - 1.3e-11 42.7 58.7 0.94 9.9 0.0 17.5 19 0 0 19 19 19 7 Leucine rich repeat LRR_6 PF13516.1 EPR78962.1 - 0.021 14.8 110.7 0.084 12.9 0.2 19.0 17 3 3 20 20 20 0 Leucine Rich repeat Aurora-A_bind PF09041.5 EPR78962.1 - 3.9 7.3 8.4 2 8.2 0.3 3.5 3 0 0 3 3 3 0 Aurora-A binding V-ATPase_H_C PF11698.3 EPR78963.1 - 5.5e-21 74.6 5.6 3.9e-19 68.7 0.1 3.7 4 0 0 4 4 4 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EPR78963.1 - 3.9e-14 52.4 8.8 3.9e-14 52.4 6.1 1.6 2 0 0 2 2 2 1 V-ATPase subunit H DUF4577 PF15145.1 EPR78963.1 - 0.0033 17.3 1.0 0.0033 17.3 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4577) Nab2 PF11517.3 EPR78963.1 - 0.23 11.5 3.5 0.42 10.7 0.4 2.8 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF1827 PF08860.5 EPR78965.1 - 0.019 15.0 1.0 0.075 13.1 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1827) DrrA_P4M PF14860.1 EPR78966.1 - 0.0033 17.1 0.6 0.0056 16.4 0.2 1.5 1 1 1 2 2 2 1 DrrA phosphatidylinositol 4-phosphate binding domain PSD2 PF07624.6 EPR78966.1 - 0.083 12.5 2.5 4.2 7.0 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1585) DUF3231 PF11553.3 EPR78969.1 - 0.12 11.9 6.9 0.43 10.0 0.6 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF3231) PNPase PF03726.9 EPR78969.1 - 1.5 9.1 6.4 0.85 9.9 0.2 3.4 2 1 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain GrpE PF01025.14 EPR78969.1 - 3 7.3 12.7 17 4.9 0.1 3.6 3 1 0 3 3 3 0 GrpE tRNA-Thr_ED PF08915.6 EPR78970.1 - 0.0079 16.1 0.2 0.0079 16.1 0.2 2.5 2 1 1 3 3 3 1 Archaea-specific editing domain of threonyl-tRNA synthetase UPF0697 PF15117.1 EPR78970.1 - 0.033 13.9 1.9 0.042 13.6 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 RNA_GG_bind PF10258.4 EPR78971.1 - 0.11 12.2 4.8 1.2 8.9 0.0 3.4 3 0 0 3 3 3 0 PHAX RNA-binding domain DUF4094 PF13334.1 EPR78971.1 - 0.12 12.7 3.0 30 5.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Bromodomain PF00439.20 EPR78972.1 - 6e-45 151.0 16.0 5.4e-23 80.7 2.1 3.3 3 0 0 3 3 3 2 Bromodomain Pox_A_type_inc PF04508.7 EPR78972.1 - 0.0013 18.2 3.3 0.0013 18.2 2.3 3.6 4 0 0 4 4 4 1 Viral A-type inclusion protein repeat Peptidase_S74 PF13884.1 EPR78972.1 - 0.019 15.0 0.8 0.019 15.0 0.6 3.2 2 1 0 2 2 2 0 Chaperone of endosialidase TSC22 PF01166.13 EPR78972.1 - 0.082 12.8 4.5 0.32 10.9 2.9 2.4 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF3373 PF11853.3 EPR78972.1 - 0.1 11.1 3.0 0.18 10.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Matrilin_ccoil PF10393.4 EPR78972.1 - 0.3 10.4 9.2 0.054 12.8 1.8 3.1 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF808 PF05661.7 EPR78972.1 - 0.41 9.4 3.2 0.69 8.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) ACCA PF03255.9 EPR78972.1 - 0.71 9.4 8.7 0.048 13.2 1.7 2.3 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit eIF-4B PF06273.6 EPR78972.1 - 1.3 7.7 5.3 2.2 6.9 3.7 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B LRR_4 PF12799.2 EPR78973.1 - 1.6e-31 107.4 81.3 1.2e-06 27.9 0.2 10.7 3 3 10 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR78973.1 - 7.7e-29 99.2 65.3 5.9e-09 35.5 4.2 7.7 3 3 5 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EPR78973.1 - 1.9e-14 51.4 80.5 0.074 13.1 0.2 15.5 15 1 2 17 17 17 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR78973.1 - 9.1e-11 40.1 40.6 1.2 9.5 0.1 13.5 14 0 0 14 14 14 5 Leucine rich repeat LRR_6 PF13516.1 EPR78973.1 - 0.00012 21.7 62.9 0.1 12.7 0.1 13.1 14 0 0 14 14 14 4 Leucine Rich repeat LRR_5 PF13306.1 EPR78973.1 - 0.0012 18.5 51.2 0.28 10.8 5.9 4.4 2 1 2 4 4 4 4 Leucine rich repeats (6 copies) KKLCAg1 PF15204.1 EPR78973.1 - 0.22 11.6 7.3 0.28 11.2 0.4 3.5 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 7TMR-HDED PF07697.6 EPR78973.1 - 2.9 7.5 6.3 0.36 10.5 0.4 2.2 2 1 1 3 3 3 0 7TM-HD extracellular TBCC PF07986.7 EPR78974.1 - 1.5e-08 34.0 7.6 1.5e-08 34.0 5.3 2.4 2 1 0 2 2 2 1 Tubulin binding cofactor C DUF1191 PF06697.7 EPR78975.1 - 0.086 11.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) GATA PF00320.22 EPR78977.1 - 1.8e-14 52.7 4.9 3.2e-14 51.9 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EPR78977.1 - 0.016 14.7 0.2 0.016 14.7 0.1 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) DZR PF12773.2 EPR78977.1 - 0.022 14.5 0.2 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EPR78977.1 - 0.051 12.8 0.3 0.16 11.3 0.2 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EPR78977.1 - 0.11 12.2 3.3 0.44 10.4 2.3 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain ArfGap PF01412.13 EPR78977.1 - 0.14 11.9 3.2 0.24 11.1 1.4 2.1 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf Per1 PF04080.8 EPR78982.1 - 6.5e-31 107.7 24.2 7.4e-31 107.5 16.8 1.0 1 0 0 1 1 1 1 Per1-like MyTH4 PF00784.12 EPR78982.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 MyTH4 domain 7TMR-DISM_7TM PF07695.6 EPR78982.1 - 0.37 10.4 30.7 2.1 7.9 8.0 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling RabGAP-TBC PF00566.13 EPR78983.1 - 1.2e-31 109.8 9.8 1.2e-31 109.8 6.8 2.6 1 1 1 3 3 3 1 Rab-GTPase-TBC domain RRF_GI PF12614.3 EPR78983.1 - 0.34 10.7 2.4 0.67 9.7 0.6 2.2 2 0 0 2 2 2 0 Ribosome recycling factor tRNA_bind PF01588.15 EPR78985.1 - 4.6e-22 77.6 0.1 9.1e-22 76.7 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DUF3381 PF11861.3 EPR78985.1 - 0.0069 15.8 0.2 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) GST_C PF00043.20 EPR78985.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PSP1 PF04468.7 EPR78986.1 - 2.8e-31 107.3 1.9 5e-31 106.5 1.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Imm14 PF15428.1 EPR78986.1 - 0.073 13.4 2.6 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 Immunity protein 14 HATPase_c_4 PF13749.1 EPR78987.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal C1_4 PF07975.7 EPR78987.1 - 0.4 10.7 2.1 0.66 10.0 0.9 1.8 2 0 0 2 2 2 0 TFIIH C1-like domain Zn_ribbon_recom PF13408.1 EPR78987.1 - 0.92 9.8 5.5 0.68 10.2 2.6 1.8 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-HIT PF04438.11 EPR78987.1 - 3.9 7.1 5.9 2.8 7.6 0.1 2.5 3 0 0 3 3 3 0 HIT zinc finger DUF1883 PF08980.5 EPR78988.1 - 0.52 9.8 4.4 0.21 11.1 1.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1883) Phage_head_chap PF11113.3 EPR78988.1 - 1.9 8.4 4.7 0.57 10.1 0.5 2.0 2 0 0 2 2 2 0 Head assembly gene product DUF718 PF05336.8 EPR78989.1 - 0.028 14.2 0.7 0.56 10.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF718) DUF4318 PF14201.1 EPR78989.1 - 0.64 9.8 3.9 1.1 9.1 2.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4318) KTI12 PF08433.5 EPR78991.1 - 3.8e-05 23.0 2.6 0.054 12.6 0.1 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 ROS_MUCR PF05443.6 EPR78991.1 - 0.033 13.9 0.1 9 6.0 0.0 2.6 2 1 1 3 3 3 0 ROS/MUCR transcriptional regulator protein Ribosomal_L7Ae PF01248.21 EPR78993.1 - 3.6e-14 52.0 1.2 4.5e-14 51.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Trns_repr_metal PF02583.12 EPR78993.1 - 0.023 14.8 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor DUF1599 PF07659.6 EPR78993.1 - 0.11 12.5 1.4 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1599) SpoU_sub_bind PF08032.7 EPR78993.1 - 0.22 11.7 3.4 20 5.4 0.0 3.1 1 1 2 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Rhodanese PF00581.15 EPR78996.1 - 2.4e-16 60.0 0.2 6.2e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DUF4131 PF13567.1 EPR78997.1 - 6.7 6.0 10.1 2.8 7.2 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) KaiC PF06745.8 EPR78998.1 - 0.058 12.5 0.6 0.068 12.2 0.4 1.2 1 0 0 1 1 1 0 KaiC XRN_N PF03159.13 EPR78999.1 - 4.6e-75 252.0 1.7 1.5e-74 250.3 1.2 1.8 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPA_C PF05181.7 EPR78999.1 - 0.026 14.0 2.8 0.15 11.6 0.1 3.3 4 0 0 4 4 4 0 XPA protein C-terminus Lipase_GDSL_3 PF14606.1 EPR78999.1 - 0.09 12.5 1.4 1.8 8.2 0.1 2.6 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TFIIB PF00382.14 EPR79000.1 - 9.5e-32 108.6 0.2 3.5e-15 55.5 0.0 2.6 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EPR79000.1 - 2.7e-09 37.1 10.2 4.9e-08 33.0 7.1 2.3 1 1 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EPR79000.1 - 6.6e-06 25.3 2.9 1e-05 24.7 1.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_24 PF13412.1 EPR79000.1 - 0.0073 15.6 1.0 0.018 14.4 0.2 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Adeno_E1A PF02703.9 EPR79000.1 - 0.016 14.6 1.8 0.047 13.1 0.4 1.9 1 1 1 2 2 2 0 Early E1A protein Sigma70_r4 PF04545.11 EPR79000.1 - 0.07 12.4 0.5 0.35 10.2 0.2 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EPR79000.1 - 0.091 12.3 0.3 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain zf-ribbon_3 PF13248.1 EPR79000.1 - 5.8 6.2 6.1 1.2 8.3 0.3 2.3 2 1 1 3 3 3 0 zinc-ribbon domain Diphthamide_syn PF01866.12 EPR79001.1 - 5e-08 32.5 0.0 1.8e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Putative diphthamide synthesis protein PMT PF02366.13 EPR79002.1 - 9.9e-58 195.3 18.8 9.9e-58 195.3 13.0 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPR79002.1 - 4.5e-12 45.9 8.1 4.2e-11 42.7 5.6 2.1 1 1 0 1 1 1 1 MIR domain DUF367 PF04034.8 EPR79003.1 - 8.7e-47 157.9 0.0 1.1e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EPR79003.1 - 7.5e-08 31.8 1.9 7.5e-08 31.8 1.3 2.2 1 1 1 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI IL34 PF15036.1 EPR79003.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Interleukin 34 DUF2540 PF10802.3 EPR79003.1 - 0.029 14.0 1.1 0.55 9.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Scm3 PF10384.4 EPR79003.1 - 0.37 10.2 1.7 8.3 5.9 0.1 2.4 2 0 0 2 2 2 0 Centromere protein Scm3 Y_phosphatase PF00102.22 EPR79004.1 - 1.5e-19 70.2 0.0 4.4e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EPR79004.1 - 2e-05 24.2 3.5 3.4e-05 23.4 0.1 2.7 1 1 2 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EPR79004.1 - 0.0005 20.1 0.1 0.0012 18.9 0.1 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EPR79004.1 - 0.1 12.8 0.1 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family vATP-synt_E PF01991.13 EPR79005.1 - 9.3e-11 41.3 20.9 8.7e-06 25.1 11.9 2.0 1 1 1 2 2 2 2 ATP synthase (E/31 kDa) subunit DUF2605 PF10792.4 EPR79005.1 - 0.098 12.3 2.1 0.13 11.9 0.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2605) SWIRM PF04433.12 EPR79005.1 - 0.66 10.1 5.0 1.4 9.0 3.4 1.8 1 1 0 1 1 1 0 SWIRM domain Exonuc_VII_L PF02601.10 EPR79005.1 - 2.1 7.4 12.7 2.4 7.2 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PUF PF00806.14 EPR79006.1 - 1.7e-54 178.3 23.6 1.3e-07 30.7 0.0 8.8 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat FANCI_S2 PF14676.1 EPR79006.1 - 0.0038 17.1 2.3 0.027 14.3 0.1 2.8 1 1 1 2 2 2 1 FANCI solenoid 2 RNase_H_2 PF13482.1 EPR79006.1 - 0.048 13.4 0.0 0.048 13.4 0.0 2.5 3 1 0 3 3 3 0 RNase_H superfamily Imm46 PF15585.1 EPR79006.1 - 0.06 13.3 1.7 0.14 12.1 0.4 2.3 2 0 0 2 2 2 0 Immunity protein 46 PWWP PF00855.12 EPR79007.1 - 8.7e-12 45.0 0.0 8.7e-12 45.0 0.0 3.3 2 1 0 2 2 2 1 PWWP domain DUF1675 PF07897.6 EPR79007.1 - 0.046 13.5 27.9 0.063 13.1 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SHS2_Rpb7-N PF03876.12 EPR79008.1 - 5.3e-08 32.8 0.0 8.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPR79008.1 - 1.2e-05 25.2 0.1 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Imm39 PF15600.1 EPR79008.1 - 0.024 14.4 0.8 0.029 14.2 0.6 1.1 1 0 0 1 1 1 0 Immunity protein 39 Choline_kinase PF01633.15 EPR79009.1 - 1.5e-37 129.2 7.9 2e-37 128.7 5.5 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EPR79009.1 - 1.5e-10 41.2 0.0 2.7e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF2777 PF10949.3 EPR79009.1 - 0.0016 18.1 1.0 0.0034 17.0 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2777) EcKinase PF02958.15 EPR79009.1 - 0.012 14.8 0.5 0.016 14.3 0.4 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3986 PF13143.1 EPR79010.1 - 0.01 16.2 0.1 0.01 16.2 0.1 3.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3986) PTPlike_phytase PF14566.1 EPR79011.1 - 8.2e-43 146.0 0.7 2.4e-33 115.3 0.3 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate KH_1 PF00013.24 EPR79013.1 - 2.2e-13 49.6 8.1 2.2e-08 33.5 0.4 3.9 4 0 0 4 4 4 2 KH domain KH_3 PF13014.1 EPR79013.1 - 2.5e-13 49.3 4.8 3.1e-08 33.0 0.7 3.1 2 0 0 2 2 2 2 KH domain Sec1 PF00995.18 EPR79014.1 - 7.2e-42 143.7 43.7 9.9e-41 140.0 30.3 2.0 1 1 0 1 1 1 1 Sec1 family HR1 PF02185.11 EPR79014.1 - 0.048 13.3 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 Hr1 repeat GSH_synthase PF03199.10 EPR79015.1 - 7e-08 32.5 1.5 6.9e-06 26.1 1.1 2.9 1 1 0 1 1 1 1 Eukaryotic glutathione synthase GSH_synth_ATP PF03917.12 EPR79015.1 - 5.8e-06 25.1 42.9 0.00041 19.0 29.7 2.3 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain LRR_8 PF13855.1 EPR79018.1 - 1.1e-24 85.9 69.2 1.3e-07 31.2 3.9 8.5 4 3 6 10 10 10 10 Leucine rich repeat LRR_4 PF12799.2 EPR79018.1 - 6.8e-22 76.6 74.1 1.5e-06 27.6 3.7 12.5 6 4 9 15 15 15 8 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPR79018.1 - 1.9e-07 30.1 23.0 0.69 10.3 0.0 11.2 11 0 0 11 11 11 2 Leucine rich repeat LRR_1 PF00560.28 EPR79018.1 - 0.00048 19.7 59.0 0.0085 15.9 0.6 12.8 15 1 0 15 15 15 5 Leucine Rich Repeat Arginosuc_synth PF00764.14 EPR79018.1 - 0.086 11.8 0.6 0.14 11.2 0.4 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase LRR_6 PF13516.1 EPR79018.1 - 1.5 9.1 47.6 1.1 9.4 0.0 10.6 11 1 1 12 12 12 0 Leucine Rich repeat Ricin_B_lectin PF00652.17 EPR79019.1 - 0.054 13.5 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Tash_PEST PF07708.6 EPR79019.1 - 0.15 12.0 4.1 0.27 11.2 2.8 1.4 1 0 0 1 1 1 0 Tash protein PEST motif HATPase_c PF02518.21 EPR79020.1 - 0.12 12.0 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EVI2A PF05399.6 EPR79021.1 - 0.16 11.1 1.8 0.19 10.9 1.2 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) LRR_4 PF12799.2 EPR79022.1 - 1.2e-11 43.9 33.5 1.8e-08 33.7 1.4 4.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79022.1 - 7.6e-11 41.6 25.3 2.3e-09 36.8 1.2 3.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EPR79022.1 - 4.8e-09 35.3 24.6 0.024 14.6 0.5 6.0 4 1 1 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.28 EPR79022.1 - 3.9e-08 32.2 23.7 0.03 14.2 0.0 6.2 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR79022.1 - 3.5e-07 29.3 14.8 0.93 9.9 0.1 6.1 6 0 0 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EPR79023.1 - 7.3e-17 60.5 28.5 8.7e-08 31.6 2.9 3.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79023.1 - 4.8e-14 51.8 22.0 5.1e-08 32.5 7.6 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EPR79023.1 - 6.9e-08 31.4 25.8 0.0007 19.2 0.3 5.9 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR79023.1 - 2.1e-07 30.0 11.9 0.051 13.7 0.1 5.7 5 1 1 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EPR79023.1 - 0.15 12.1 24.2 0.29 11.3 0.5 5.4 4 2 2 6 6 6 0 Leucine Rich repeat Patatin PF01734.17 EPR79024.1 - 4.8e-16 59.2 0.0 1e-15 58.2 0.0 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase HTH_AraC PF00165.18 EPR79024.1 - 0.042 13.6 1.1 0.48 10.3 0.5 2.8 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family LRR_4 PF12799.2 EPR79025.1 - 2.3e-26 90.8 45.7 6.5e-10 38.4 0.7 6.5 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79025.1 - 8.3e-22 76.7 55.6 4.8e-09 35.8 1.0 5.1 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EPR79025.1 - 1.7e-15 54.6 46.8 0.074 13.1 0.3 10.6 8 1 2 10 10 10 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR79025.1 - 9.8e-14 49.0 31.1 0.42 11.0 0.0 10.0 10 0 0 10 10 10 7 Leucine rich repeat LRR_6 PF13516.1 EPR79025.1 - 1.6e-08 33.7 43.6 0.36 11.0 1.1 10.1 9 1 1 10 10 10 7 Leucine Rich repeat LRR_8 PF13855.1 EPR79026.1 - 2.9e-17 62.1 16.6 2.9e-09 36.5 2.0 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EPR79026.1 - 2.1e-12 46.3 22.1 4.8e-07 29.2 1.2 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79026.1 - 1e-07 30.9 17.3 0.00057 19.5 0.3 5.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR79026.1 - 0.00017 21.2 10.1 0.036 14.2 0.2 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EPR79026.1 - 0.0015 18.3 11.4 0.055 13.5 0.1 4.4 5 0 0 5 5 5 2 Leucine Rich repeat Pas_Saposin PF09016.5 EPR79026.1 - 0.0046 16.9 0.4 1.9 8.5 0.0 2.8 1 1 1 2 2 2 2 Pas factor saposin fold UCH PF00443.24 EPR79026.1 - 0.085 11.9 1.4 0.17 10.9 0.9 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase KIP1 PF07765.7 EPR79026.1 - 0.15 11.9 1.0 0.41 10.5 0.7 1.8 1 0 0 1 1 1 0 KIP1-like protein DUF1757 PF08560.5 EPR79027.1 - 0.011 15.4 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Poxvirus_B22R_C PF13168.1 EPR79027.1 - 0.18 11.0 0.8 0.27 10.4 0.5 1.4 1 1 0 1 1 1 0 Poxvirus B22R protein C-terminal Urm1 PF09138.6 EPR79029.1 - 0.29 11.2 1.6 0.44 10.7 1.1 1.3 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) MutS_I PF01624.15 EPR79030.1 - 4.3e-33 113.6 0.2 8.8e-33 112.7 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 EPR79030.1 - 6.7e-08 32.5 0.7 1.5e-07 31.4 0.3 1.8 2 0 0 2 2 2 1 MutS domain III TFIID_20kDa PF03847.8 EPR79032.1 - 2.3e-10 40.5 0.2 3.3e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EPR79032.1 - 0.00023 21.1 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPR79032.1 - 0.0025 17.6 0.1 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EPR79032.1 - 0.0066 16.4 0.1 0.024 14.6 0.0 1.9 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_30kDa PF03540.8 EPR79032.1 - 0.067 13.0 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EPR79032.1 - 0.11 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EPR79032.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L24e PF01246.15 EPR79033.1 - 4.4e-08 32.8 1.3 4.4e-08 32.8 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Peptidase_M8 PF01457.11 EPR79033.1 - 0.026 12.8 0.4 0.031 12.6 0.3 1.0 1 0 0 1 1 1 0 Leishmanolysin DUF1221 PF06760.6 EPR79033.1 - 0.045 12.9 2.0 0.094 11.9 1.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1221) TypeIII_RM_meth PF12564.3 EPR79034.1 - 7.7 6.5 8.6 8.4 6.4 0.4 3.3 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit Sad1_UNC PF07738.8 EPR79035.1 - 6.9e-08 32.3 1.9 7.7e-07 28.9 0.0 2.5 2 1 0 3 3 3 1 Sad1 / UNC-like C-terminal Apc15p PF05841.6 EPR79035.1 - 0.052 14.2 8.0 1.5 9.5 3.7 2.2 2 0 0 2 2 2 0 Apc15p protein Mucin PF01456.12 EPR79035.1 - 8.8 6.0 15.6 5.7 6.7 5.3 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein ArfGap PF01412.13 EPR79036.1 - 1.4e-27 95.8 2.1 1.4e-27 95.8 1.4 3.4 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf Mucin PF01456.12 EPR79036.1 - 0.0002 21.1 17.7 0.00035 20.3 12.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-B_box PF00643.19 EPR79036.1 - 0.018 14.8 0.7 0.027 14.3 0.5 1.3 1 0 0 1 1 1 0 B-box zinc finger Tmp39 PF10271.4 EPR79039.1 - 0.00061 18.5 0.4 0.00084 18.1 0.3 1.2 1 0 0 1 1 1 1 Putative transmembrane protein DUF1240 PF06836.7 EPR79039.1 - 0.19 11.9 2.1 0.2 11.8 0.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) Late_protein_L2 PF00513.13 EPR79040.1 - 0.037 12.8 12.0 0.047 12.5 8.3 1.1 1 0 0 1 1 1 0 Late Protein L2 DUF2362 PF10154.4 EPR79040.1 - 0.046 12.3 19.0 0.053 12.1 13.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Pkinase PF00069.20 EPR79041.1 - 4.8e-45 153.7 0.7 7.8e-45 153.0 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79041.1 - 5.6e-22 78.0 0.0 7.8e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79041.1 - 2.1e-05 23.6 0.0 3.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPR79041.1 - 0.038 13.7 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family NIF PF03031.13 EPR79042.1 - 2.4e-20 72.7 15.2 7.4e-19 67.9 1.8 3.5 2 2 2 4 4 4 2 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EPR79042.1 - 0.0022 18.2 0.0 0.05 13.8 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SRP54 PF00448.17 EPR79043.1 - 3.7e-49 166.8 3.3 1.5e-47 161.6 2.3 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EPR79043.1 - 0.0026 17.3 0.1 0.013 15.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain GTP_cyclohydroI PF01227.17 EPR79043.1 - 0.0091 15.3 0.4 3.2 6.9 0.0 2.3 2 0 0 2 2 2 2 GTP cyclohydrolase I AAA PF00004.24 EPR79043.1 - 0.017 15.2 1.6 0.072 13.2 1.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPR79043.1 - 0.03 14.0 2.9 0.038 13.7 0.5 2.3 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPR79043.1 - 0.034 14.2 1.8 0.21 11.7 0.5 2.7 1 1 2 3 3 3 0 AAA domain cobW PF02492.14 EPR79043.1 - 0.036 13.4 7.9 0.27 10.6 5.5 2.0 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain YqgF PF14639.1 EPR79043.1 - 0.097 12.2 2.1 3.9 7.0 0.5 2.3 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 AAA_18 PF13238.1 EPR79043.1 - 0.3 11.3 5.2 0.4 10.9 1.2 2.4 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPR79043.1 - 0.67 9.9 10.9 2.5 8.0 7.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EPR79043.1 - 2.9 7.8 6.6 6.5 6.6 2.6 3.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EPR79043.1 - 4.7 7.5 6.0 9.5 6.5 4.1 1.6 1 1 0 1 1 1 0 ABC transporter AMP-binding PF00501.23 EPR79044.1 - 1.2e-56 191.9 0.1 4.9e-23 81.2 0.0 3.9 4 0 0 4 4 4 3 AMP-binding enzyme AMP-binding_C PF13193.1 EPR79044.1 - 2.8e-13 50.6 0.0 4.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_45 PF14947.1 EPR79045.1 - 1.2 9.0 8.3 1 9.1 4.7 1.7 1 1 0 1 1 1 0 Winged helix-turn-helix WD40 PF00400.27 EPR79046.1 - 2.2e-26 90.6 2.7 8.1e-07 28.6 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EPR79046.1 - 3.2e-06 26.9 3.6 0.0018 18.0 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EPR79046.1 - 0.0011 18.6 1.1 0.0049 16.6 0.1 2.4 2 1 2 4 4 4 1 Transcription factor IIIC subunit delta N-term BBS2_Mid PF14783.1 EPR79046.1 - 0.062 13.0 0.9 0.68 9.7 0.2 2.9 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nbas_N PF15492.1 EPR79046.1 - 0.067 12.2 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal NYD-SP28_assoc PF14775.1 EPR79046.1 - 0.33 10.6 2.3 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF872 PF05915.7 EPR79047.1 - 0.022 14.6 0.4 0.022 14.6 0.3 3.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Exo_endo_phos PF03372.18 EPR79048.1 - 3.2e-20 73.1 0.0 4.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EPR79048.1 - 4.6e-18 64.4 35.6 3e-08 33.0 4.2 4.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79048.1 - 1.9e-10 40.3 17.5 1.1e-06 28.2 3.6 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPR79048.1 - 1.6e-06 27.2 22.6 0.027 14.4 0.2 6.2 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPR79048.1 - 0.016 15.2 16.0 1.2 9.6 0.2 5.6 6 1 0 6 6 6 0 Leucine rich repeat Exo_endo_phos_2 PF14529.1 EPR79048.1 - 0.027 14.0 0.1 0.2 11.2 0.0 2.6 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase LRR_6 PF13516.1 EPR79048.1 - 1 9.6 16.8 2 8.7 0.1 5.6 4 1 1 5 5 5 0 Leucine Rich repeat DnaJ PF00226.26 EPR79049.1 - 1.9e-15 56.3 1.0 3.8e-15 55.3 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 EPR79049.1 - 0.075 13.5 4.6 2.2 8.7 1.0 2.9 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain PEPcase_2 PF14010.1 EPR79049.1 - 0.15 10.3 1.7 0.19 10.0 1.2 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase ArsA_ATPase PF02374.10 EPR79049.1 - 0.4 9.6 2.9 0.66 8.9 2.0 1.4 1 1 0 1 1 1 0 Anion-transporting ATPase RRM_1 PF00076.17 EPR79050.1 - 3.4e-15 55.4 0.7 1.7e-14 53.1 0.0 2.5 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EPR79050.1 - 6.7e-14 51.7 3.7 6.7e-14 51.7 2.6 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_6 PF14259.1 EPR79050.1 - 1.1e-09 38.1 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79050.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFX_C PF14601.1 EPR79050.1 - 0.18 11.5 2.7 0.4 10.4 0.3 2.3 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term AAA_23 PF13476.1 EPR79050.1 - 0.41 10.9 7.9 0.49 10.6 5.5 1.2 1 0 0 1 1 1 0 AAA domain DUF1667 PF07892.6 EPR79050.1 - 0.63 9.7 7.0 0.16 11.7 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1667) KOW PF00467.24 EPR79051.1 - 2.6e-06 26.9 3.2 2.6e-06 26.9 2.2 1.8 2 0 0 2 2 2 1 KOW motif eIF-1a PF01176.14 EPR79051.1 - 0.34 10.3 2.7 0.57 9.6 0.4 2.3 3 0 0 3 3 3 0 Translation initiation factor 1A / IF-1 zf-DHHC PF01529.15 EPR79052.1 - 1.1e-30 106.3 19.3 1.1e-30 106.3 13.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Sre PF03125.13 EPR79052.1 - 0.006 15.5 18.7 0.025 13.4 7.4 2.1 2 0 0 2 2 2 2 C. elegans Sre G protein-coupled chemoreceptor Ndc1_Nup PF09531.5 EPR79052.1 - 0.2 10.0 4.2 0.28 9.5 2.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DZR PF12773.2 EPR79052.1 - 0.21 11.4 6.2 0.35 10.7 4.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon GTP_EFTU PF00009.22 EPR79054.1 - 1.9e-30 105.6 0.3 1.9e-30 105.6 0.2 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPR79054.1 - 3.6e-16 59.0 2.3 3.6e-16 59.0 1.6 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPR79054.1 - 7.7e-10 38.7 16.1 9.7e-08 32.0 0.2 4.2 3 1 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPR79054.1 - 1.6e-06 28.0 0.0 1.6e-06 28.0 0.0 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EPR79054.1 - 2.3e-06 27.1 0.6 2.3e-06 27.1 0.4 3.2 4 0 0 4 4 4 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EPR79054.1 - 0.0062 16.1 0.0 0.0062 16.1 0.0 2.6 3 1 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPR79054.1 - 0.039 14.0 1.0 0.86 9.7 0.3 3.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPR79054.1 - 0.19 11.6 0.8 0.8 9.6 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain zf-C3HC4_3 PF13920.1 EPR79055.1 - 1.1e-08 34.6 6.1 1.9e-08 33.8 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR79055.1 - 1e-07 31.8 9.7 1.9e-07 30.9 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR79055.1 - 2e-07 30.5 10.0 4.4e-07 29.4 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPR79055.1 - 3.1e-06 26.9 7.1 5.4e-06 26.1 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPR79055.1 - 1.1e-05 25.0 8.6 2e-05 24.1 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EPR79055.1 - 4.2e-05 23.2 3.1 7.8e-05 22.3 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EPR79055.1 - 0.00025 21.1 1.8 0.00063 19.8 1.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EPR79055.1 - 0.00036 20.0 2.4 0.00073 19.0 1.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EPR79055.1 - 0.0015 18.1 4.3 0.0039 16.8 2.0 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EPR79055.1 - 0.044 13.3 2.6 0.15 11.5 1.8 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EPR79055.1 - 0.048 13.5 7.8 0.11 12.3 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EPR79055.1 - 0.47 10.3 4.9 1 9.2 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2H2 PF00096.21 EPR79055.1 - 0.64 10.4 5.2 11 6.5 0.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.1 EPR79055.1 - 1.8 8.2 6.6 3.7 7.2 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 EPR79055.1 - 1.9 8.2 6.5 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Baculo_IE-1 PF05290.6 EPR79055.1 - 3.1 7.5 17.7 0.015 15.0 2.8 3.3 2 1 2 4 4 4 0 Baculovirus immediate-early protein (IE-0) Apolipoprotein PF01442.13 EPR79056.1 - 0.042 13.3 0.5 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain Phasin PF05597.6 EPR79056.1 - 0.65 9.7 6.4 8.7 6.1 0.3 3.9 3 1 1 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sec8_exocyst PF04048.9 EPR79056.1 - 8.2 6.0 9.5 4 7.0 0.6 3.2 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Ribosomal_L5_C PF00673.16 EPR79057.1 - 1.5e-21 75.9 0.3 2.3e-21 75.3 0.2 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPR79057.1 - 6.6e-14 51.4 2.8 1.2e-13 50.5 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 NOB1_Zn_bind PF08772.6 EPR79059.1 - 5.6e-10 38.8 1.6 1.1e-09 37.9 1.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 EPR79059.1 - 0.046 13.5 0.2 0.082 12.7 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.6 EPR79059.1 - 0.14 11.7 0.3 2.9 7.4 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ETRAMP PF09716.5 EPR79062.1 - 0.051 13.5 0.2 0.051 13.5 0.1 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MIF4G PF02854.14 EPR79063.1 - 2.7e-09 36.7 14.7 2.7e-09 36.7 10.2 2.6 2 0 0 2 2 2 1 MIF4G domain DUF1212 PF06738.7 EPR79063.1 - 0.56 9.6 2.8 1.2 8.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) zf-U1 PF06220.7 EPR79066.1 - 9.9e-11 41.0 2.7 1.8e-10 40.1 1.9 1.5 1 0 0 1 1 1 1 U1 zinc finger GFA PF04828.9 EPR79066.1 - 0.05 13.5 0.5 2.5 8.1 0.1 2.3 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-met PF12874.2 EPR79066.1 - 3.4 8.0 7.2 6.6 7.0 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPR79066.1 - 4.5 7.5 7.2 28 4.9 5.0 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding EF-hand_7 PF13499.1 EPR79067.1 - 4.6e-12 45.8 2.4 3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPR79067.1 - 3.6e-09 35.7 3.6 0.00023 20.7 0.1 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EPR79067.1 - 3.3e-08 32.9 2.8 0.00028 20.4 0.2 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 EPR79067.1 - 1.3e-06 28.2 0.0 8.9e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EPR79067.1 - 1.7e-05 23.7 5.5 0.00058 18.9 0.2 4.1 4 0 0 4 4 4 1 EF hand Utp8 PF10395.4 EPR79067.1 - 0.015 13.6 2.9 0.016 13.5 2.0 1.0 1 0 0 1 1 1 0 Utp8 family DUF3647 PF12363.3 EPR79067.1 - 0.022 14.8 2.9 0.026 14.6 0.9 1.8 2 0 0 2 2 2 0 Phage protein Lip_prot_lig_C PF10437.4 EPR79067.1 - 0.027 14.1 3.9 0.079 12.6 1.3 2.4 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus RsbU_N PF08673.5 EPR79067.1 - 0.085 12.8 0.5 0.42 10.6 0.1 2.3 1 1 1 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain Pox_VLTF3 PF04947.9 EPR79067.1 - 0.11 12.0 4.2 0.39 10.2 0.7 2.2 1 1 1 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like DUF3349 PF11829.3 EPR79067.1 - 0.12 12.8 0.0 1.3 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) DUF1160 PF06648.6 EPR79067.1 - 0.13 12.0 2.2 0.23 11.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1160) SapB_1 PF05184.10 EPR79067.1 - 3.9 7.4 6.5 0.7 9.7 0.1 2.7 3 0 0 3 3 3 0 Saposin-like type B, region 1 Na_H_Exchanger PF00999.16 EPR79068.1 - 3.2e-48 164.1 33.1 3.9e-48 163.8 22.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EPR79068.1 - 3.6 7.5 13.2 2.3 8.2 0.6 3.1 3 0 0 3 3 3 0 YrhC-like protein LRR_4 PF12799.2 EPR79070.1 - 1.7e-37 126.4 51.1 1e-06 28.2 0.1 8.1 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79070.1 - 1.4e-28 98.4 48.5 3.1e-09 36.4 2.0 7.3 3 3 4 7 7 7 7 Leucine rich repeat LRR_7 PF13504.1 EPR79070.1 - 3.7e-15 53.3 29.3 2.6 8.6 0.1 14.2 15 0 0 15 15 15 5 Leucine rich repeat LRR_1 PF00560.28 EPR79070.1 - 5.8e-14 49.9 55.4 0.13 12.3 0.1 14.1 12 1 2 14 14 14 9 Leucine Rich Repeat LRR_6 PF13516.1 EPR79070.1 - 1.1e-06 28.0 39.4 0.042 13.9 0.1 12.0 11 2 1 12 12 12 2 Leucine Rich repeat LRR_4 PF12799.2 EPR79071.1 - 3.3e-26 90.4 101.3 1.7e-08 33.8 2.8 11.6 8 2 2 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79071.1 - 3.8e-26 90.6 75.9 4.5e-08 32.7 6.2 9.4 7 3 5 12 12 12 7 Leucine rich repeat LRR_1 PF00560.28 EPR79071.1 - 1.1e-10 39.9 78.7 0.027 14.4 0.6 15.2 15 2 0 15 15 15 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR79071.1 - 4.5e-07 29.0 48.0 1.5 9.3 0.1 13.0 14 1 0 14 14 14 6 Leucine rich repeat LRR_6 PF13516.1 EPR79071.1 - 0.00024 20.8 62.6 0.17 12.0 0.2 13.1 13 2 0 13 13 13 5 Leucine Rich repeat Put_DNA-bind_N PF06971.8 EPR79071.1 - 0.022 14.5 0.0 0.095 12.4 0.0 2.2 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus UPF0086 PF01868.11 EPR79072.1 - 2.4e-06 27.0 0.2 5.1e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 CRF PF00473.12 EPR79073.1 - 0.032 14.3 0.2 0.098 12.7 0.1 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family Cob_adeno_trans PF01923.13 EPR79073.1 - 0.26 11.0 3.1 0.42 10.3 0.4 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DivIC PF04977.10 EPR79073.1 - 0.89 9.0 18.0 1.5 8.3 0.4 3.8 4 0 0 4 4 4 0 Septum formation initiator HBS1_N PF08938.5 EPR79073.1 - 1.8 8.7 8.8 0.65 10.1 3.2 2.6 2 1 0 2 2 2 0 HBS1 N-terminus DUF1515 PF07439.6 EPR79073.1 - 2.2 8.1 4.9 1.2 8.9 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) MutS_III PF05192.13 EPR79073.1 - 3.5 7.3 7.1 1.5 8.5 3.4 1.4 1 1 0 1 1 1 0 MutS domain III Dynamitin PF04912.9 EPR79075.1 - 0.063 12.0 1.4 2.6 6.7 0.0 2.5 1 1 2 3 3 3 0 Dynamitin LRR_8 PF13855.1 EPR79076.1 - 6.9e-15 54.5 34.3 2e-06 27.4 3.6 5.1 4 2 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 EPR79076.1 - 1.6e-10 40.3 36.4 6.8e-06 25.5 1.5 5.5 5 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79076.1 - 8.1e-06 25.1 24.7 0.87 9.8 0.0 7.8 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR79076.1 - 0.034 14.3 11.9 3.1 8.3 0.0 6.2 8 0 0 8 8 8 0 Leucine rich repeat UQ_con PF00179.21 EPR79077.1 - 2e-37 127.7 0.1 2.1e-37 127.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme tRNA-synt_1c PF00749.16 EPR79078.1 - 5.6e-97 324.1 0.0 8.8e-97 323.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPR79078.1 - 3.4e-33 114.7 0.3 3.4e-33 114.7 0.2 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain GatB_Yqey PF02637.13 EPR79078.1 - 0.0054 16.4 1.5 0.025 14.2 0.6 2.4 2 0 0 2 2 2 1 GatB domain V-SNARE PF05008.10 EPR79079.1 - 0.007 16.5 1.2 0.21 11.7 0.1 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF869 PF05911.6 EPR79079.1 - 0.18 10.0 5.2 0.23 9.6 3.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4285 PF14113.1 EPR79079.1 - 1.1 9.2 6.4 0.58 10.1 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4285) PLAC8 PF04749.12 EPR79080.1 - 2 9.0 5.0 22 5.6 3.6 2.1 1 1 1 2 2 2 0 PLAC8 family CDC50 PF03381.10 EPR79081.1 - 3.5e-44 151.0 1.4 4.6e-44 150.6 1.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2823 PF11034.3 EPR79081.1 - 0.069 13.2 0.6 0.12 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2823) Arv1 PF04161.8 EPR79082.1 - 1.1e-13 51.6 13.2 2.3e-13 50.5 9.1 1.6 1 1 0 1 1 1 1 Arv1-like family ABC_tran PF00005.22 EPR79083.1 - 7.6e-25 87.7 0.0 1.3e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPR79083.1 - 3e-10 40.5 0.7 3e-10 40.5 0.5 3.8 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.1 EPR79083.1 - 1.4e-06 27.6 0.0 0.0087 15.1 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain SMC_N PF02463.14 EPR79083.1 - 1.4e-05 24.4 2.3 7.1e-05 22.1 0.3 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPR79083.1 - 0.00019 22.1 0.1 0.00061 20.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EPR79083.1 - 0.0004 19.8 0.1 0.0015 17.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPR79083.1 - 0.0012 18.2 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EPR79083.1 - 0.0019 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 EPR79083.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPR79083.1 - 0.0038 17.3 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPR79083.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPR79083.1 - 0.012 15.9 0.3 0.034 14.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EPR79083.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPR79083.1 - 0.028 14.0 0.2 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EPR79083.1 - 0.033 13.9 0.2 0.075 12.7 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EPR79083.1 - 0.048 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPR79083.1 - 0.07 12.5 0.5 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 EPR79083.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EPR79083.1 - 0.075 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EPR79083.1 - 0.084 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EPR79083.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EPR79083.1 - 0.1 12.4 0.2 0.22 11.3 0.1 1.6 1 1 0 1 1 1 0 Dynamin family NTPase_1 PF03266.10 EPR79083.1 - 0.11 12.1 0.3 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EPR79083.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EPR79083.1 - 1.4 9.2 9.8 11 6.2 6.8 2.5 1 1 0 1 1 1 0 AAA domain EamA PF00892.15 EPR79084.1 - 0.0079 16.2 9.5 0.0079 16.2 6.6 3.1 1 1 1 3 3 3 1 EamA-like transporter family Pkinase PF00069.20 EPR79085.1 - 1.9e-35 122.2 0.0 7.7e-35 120.2 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79085.1 - 1.3e-12 47.3 0.0 2.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79085.1 - 0.00022 20.3 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF1510 PF07423.6 EPR79086.1 - 0.00015 21.2 2.7 0.00018 20.9 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) ABC2_membrane_3 PF12698.2 EPR79086.1 - 0.0084 15.1 0.9 0.0095 14.9 0.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1312 PF07009.6 EPR79086.1 - 0.019 14.7 7.4 0.087 12.6 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1312) Chordopox_A13L PF05961.6 EPR79086.1 - 0.023 14.6 1.1 0.023 14.6 0.7 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein IncA PF04156.9 EPR79086.1 - 0.028 14.0 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein Tetraspannin PF00335.15 EPR79086.1 - 0.03 13.6 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF2615 PF11027.3 EPR79086.1 - 0.055 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Ly49 PF08391.5 EPR79086.1 - 0.062 13.4 7.1 0.08 13.0 4.9 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region YjgP_YjgQ PF03739.9 EPR79086.1 - 0.078 11.7 1.7 0.094 11.4 1.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Claudin_2 PF13903.1 EPR79086.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 EPR79086.1 - 0.14 12.5 0.3 0.14 12.5 0.2 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3959 PF13105.1 EPR79086.1 - 0.32 10.2 6.3 0.49 9.6 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF2500 PF10694.4 EPR79086.1 - 0.59 10.1 4.9 1.7 8.6 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) LicD PF04991.8 EPR79086.1 - 7.2 6.6 12.8 8.7 6.3 8.9 1.0 1 0 0 1 1 1 0 LicD family EamA PF00892.15 EPR79087.1 - 0.18 11.8 32.4 0.62 10.1 9.1 2.8 2 1 0 2 2 2 0 EamA-like transporter family Imm2 PF14426.1 EPR79088.1 - 0.15 12.0 2.3 0.96 9.4 0.1 2.4 2 0 0 2 2 2 0 Immunity protein Imm2 DUF2664 PF10867.3 EPR79088.1 - 0.2 12.2 1.4 0.28 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) CR6_interact PF10147.4 EPR79088.1 - 3.6 6.8 11.2 1.4 8.1 0.5 2.1 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 SNF2_N PF00176.18 EPR79089.1 - 3.5e-68 229.6 1.0 3.5e-68 229.6 0.7 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPR79089.1 - 2e-14 53.2 0.1 1.1e-13 50.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 EPR79089.1 - 5.6e-08 32.3 11.0 9.2e-06 25.2 0.7 3.8 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EPR79089.1 - 5.4e-06 26.0 0.1 2.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AT_hook PF02178.14 EPR79089.1 - 0.034 13.7 3.7 0.11 12.1 2.6 2.0 1 0 0 1 1 1 0 AT hook motif Mitofilin PF09731.4 EPR79091.1 - 0.00072 18.3 6.5 0.00087 18.0 4.5 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein BAR_2 PF10455.4 EPR79091.1 - 0.00085 18.3 11.3 0.0017 17.3 7.8 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking CCDC-167 PF15188.1 EPR79091.1 - 0.022 14.6 5.8 2.3 8.2 1.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Atg14 PF10186.4 EPR79091.1 - 0.046 12.6 2.4 0.067 12.1 1.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IMD PF08397.6 EPR79091.1 - 0.057 12.7 11.4 0.11 11.8 6.3 2.2 1 1 1 2 2 2 0 IRSp53/MIM homology domain bZIP_Maf PF03131.12 EPR79091.1 - 0.065 13.5 4.9 0.11 12.7 2.4 2.0 2 1 0 2 2 2 0 bZIP Maf transcription factor FbpA PF05833.6 EPR79091.1 - 0.099 11.1 8.6 0.047 12.2 4.5 1.5 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) GLTP PF08718.6 EPR79091.1 - 0.1 12.6 1.6 0.19 11.7 1.1 1.5 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF1090 PF06476.7 EPR79091.1 - 0.16 11.5 4.8 0.36 10.4 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF1664 PF07889.7 EPR79091.1 - 0.19 11.5 5.7 1.2 8.9 2.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EPR79091.1 - 0.22 11.9 5.6 3 8.2 0.3 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal GBP_C PF02841.9 EPR79091.1 - 0.33 10.0 11.1 0.47 9.5 7.5 1.4 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain INTS5_N PF14837.1 EPR79091.1 - 0.46 9.8 2.3 0.75 9.1 1.6 1.4 1 1 0 1 1 1 0 Integrator complex subunit 5 N-terminus DUF573 PF04504.9 EPR79091.1 - 0.85 9.9 7.0 0.33 11.2 2.6 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF573 TPR_MLP1_2 PF07926.7 EPR79091.1 - 0.93 9.2 11.6 4.3 7.1 8.0 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Rogdi_lz PF10259.4 EPR79094.1 - 0.0019 17.3 0.7 0.0024 17.0 0.5 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Cob_adeno_trans PF01923.13 EPR79094.1 - 0.0029 17.3 3.5 0.0038 17.0 2.4 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase F_actin_bind PF08919.5 EPR79094.1 - 0.025 14.2 1.4 0.038 13.7 1.0 1.3 1 0 0 1 1 1 0 F-actin binding HrcA PF01628.16 EPR79094.1 - 0.059 12.9 4.2 0.076 12.5 2.9 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain Baculo_PEP_C PF04513.7 EPR79094.1 - 0.075 12.8 0.6 0.096 12.5 0.4 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_32 PF13654.1 EPR79094.1 - 0.39 9.3 17.0 0.49 8.9 11.8 1.0 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EPR79094.1 - 1.1 9.0 7.0 0.19 11.4 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUN14 PF04930.10 EPR79094.1 - 1.4 9.2 5.7 11 6.3 3.9 2.2 1 1 0 1 1 1 0 FUN14 family FlxA PF14282.1 EPR79094.1 - 1.5 8.8 10.1 2.1 8.3 7.0 1.3 1 0 0 1 1 1 0 FlxA-like protein Herpes_UL92 PF03048.9 EPR79094.1 - 2.2 7.7 5.2 0.21 11.1 0.4 1.6 2 0 0 2 2 2 0 UL92 family DUF755 PF05501.6 EPR79094.1 - 3 7.9 8.3 5 7.2 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AAA_23 PF13476.1 EPR79094.1 - 3.1 8.0 17.5 4.1 7.6 12.1 1.2 1 0 0 1 1 1 0 AAA domain DDHD PF02862.12 EPR79094.1 - 4.2 7.1 8.0 4.8 6.9 5.5 1.1 1 0 0 1 1 1 0 DDHD domain ISG65-75 PF11727.3 EPR79094.1 - 9.8 5.1 15.6 3.2 6.7 7.4 1.8 1 1 1 2 2 2 0 Invariant surface glycoprotein NinG PF05766.7 EPR79096.1 - 0.0068 16.1 0.3 0.02 14.6 0.2 1.8 1 0 0 1 1 1 1 Bacteriophage Lambda NinG protein Tup_N PF08581.5 EPR79096.1 - 0.13 12.5 3.0 2.1 8.6 0.0 3.3 3 0 0 3 3 3 0 Tup N-terminal IncA PF04156.9 EPR79096.1 - 3.5 7.1 6.1 0.39 10.2 0.9 1.8 2 1 0 2 2 2 0 IncA protein GSHPx PF00255.14 EPR79097.1 - 8.1e-35 118.4 0.8 1.1e-34 118.0 0.5 1.2 1 0 0 1 1 1 1 Glutathione peroxidase DUF648 PF04890.8 EPR79097.1 - 0.081 12.0 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF648) Pkinase PF00069.20 EPR79098.1 - 6.8e-65 218.7 0.4 7.8e-65 218.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79098.1 - 1.7e-36 125.6 0.1 2.1e-36 125.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79098.1 - 0.001 18.1 0.0 0.19 10.6 0.0 2.4 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EPR79098.1 - 0.0058 16.0 0.1 0.012 15.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EPR79098.1 - 0.0088 15.7 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPR79098.1 - 0.016 14.2 0.0 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2972 PF11186.3 EPR79098.1 - 0.35 10.7 5.3 0.48 10.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) Ribosomal_S13 PF00416.17 EPR79099.1 - 4.4e-25 88.1 0.6 5.4e-25 87.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPR79099.1 - 0.0015 17.1 0.0 0.0018 16.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3659 PF12396.3 EPR79099.1 - 0.057 13.0 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Sec5 PF15469.1 EPR79100.1 - 1.1e-05 25.2 19.9 1.1e-05 25.2 13.8 3.8 3 2 0 3 3 3 1 Exocyst complex component Sec5 HTH_9 PF08221.6 EPR79100.1 - 0.095 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Sec8_exocyst PF04048.9 EPR79101.1 - 9e-06 25.3 3.1 9e-06 25.3 2.1 2.1 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain Mt_ATP-synt_B PF05405.9 EPR79101.1 - 0.0027 17.1 2.8 0.0061 16.0 1.9 1.6 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) IncA PF04156.9 EPR79101.1 - 0.033 13.7 1.2 0.063 12.8 0.8 1.5 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 EPR79101.1 - 0.056 13.1 8.0 0.099 12.3 2.7 2.5 1 1 0 2 2 2 0 Laminin Domain II Nsp1_C PF05064.8 EPR79101.1 - 0.095 12.3 6.7 0.061 12.9 2.4 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region CCDC155 PF14662.1 EPR79101.1 - 0.12 11.9 10.1 0.24 10.9 7.0 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF745 PF05335.8 EPR79101.1 - 0.69 9.4 5.6 0.12 11.8 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) zf-C2H2 PF00096.21 EPR79102.1 - 1.4e-05 25.1 18.9 0.014 15.6 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPR79102.1 - 4.4e-05 23.5 14.2 0.044 14.1 1.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPR79102.1 - 0.00026 21.0 2.9 0.18 11.9 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Arm_2 PF04826.8 EPR79102.1 - 0.13 11.3 1.6 0.19 10.7 1.1 1.2 1 0 0 1 1 1 0 Armadillo-like zf-BED PF02892.10 EPR79102.1 - 0.18 11.5 7.2 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 EPR79102.1 - 1.2 9.5 15.4 0.14 12.4 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Ndc80_HEC PF03801.8 EPR79103.1 - 4.2e-43 146.5 0.5 4.9e-43 146.3 0.3 1.0 1 0 0 1 1 1 1 HEC/Ndc80p family Saccharop_dh PF03435.13 EPR79104.1 - 1.5e-20 73.5 0.3 9.6e-20 70.9 0.2 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase P2 PF07194.6 EPR79104.1 - 0.0055 16.5 1.4 1.5 8.7 0.0 2.9 3 0 0 3 3 3 2 P2 response regulator binding domain G10 PF01125.12 EPR79106.1 - 3.9e-38 130.2 8.1 4.6e-38 130.0 5.6 1.0 1 0 0 1 1 1 1 G10 protein DUF788 PF05620.6 EPR79108.1 - 0.2 11.5 4.0 0.088 12.6 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF788) DUF1430 PF07242.6 EPR79108.1 - 8.4 6.5 14.2 0.48 10.5 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1430) DUF2198 PF09964.4 EPR79108.1 - 9 6.1 8.0 0.4 10.4 0.2 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) Ribosomal_S14 PF00253.16 EPR79109.1 - 1.3e-15 56.4 4.0 1.5e-15 56.2 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Defensin_3 PF08131.6 EPR79109.1 - 0.054 13.4 1.2 0.075 13.0 0.8 1.2 1 0 0 1 1 1 0 Defensin-like peptide family Ribosomal_L40e PF01020.12 EPR79109.1 - 5.8 6.5 6.5 17 5.1 0.2 2.4 1 1 1 2 2 2 0 Ribosomal L40e family Reo_sigmaC PF04582.7 EPR79110.1 - 1 8.4 3.2 3.7 6.6 0.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EPR79110.1 - 1.4 8.5 65.4 0.6 9.6 10.4 4.1 1 1 2 3 3 3 0 IncA protein TFIID-18kDa PF02269.11 EPR79112.1 - 5.3e-26 90.2 0.4 1e-25 89.3 0.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EPR79112.1 - 0.00017 21.5 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR79112.1 - 0.0025 17.8 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Chordopox_A30L PF06015.7 EPR79112.1 - 1.4 8.6 4.6 15 5.2 0.3 3.1 3 0 0 3 3 3 0 Chordopoxvirus A30L protein zf-Tim10_DDP PF02953.10 EPR79113.1 - 0.13 11.5 0.5 0.33 10.2 0.0 1.9 2 0 0 2 2 2 0 Tim10/DDP family zinc finger XPA_C PF05181.7 EPR79114.1 - 1.9e-17 62.5 1.5 6.6e-17 60.8 0.4 2.2 2 0 0 2 2 2 1 XPA protein C-terminus SNARE PF05739.14 EPR79115.1 - 0.00023 20.7 1.0 0.00028 20.5 0.7 1.1 1 0 0 1 1 1 1 SNARE domain TPR_MLP1_2 PF07926.7 EPR79115.1 - 0.0029 17.3 2.9 0.0034 17.1 2.0 1.0 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Prominin PF05478.6 EPR79115.1 - 0.004 14.7 1.7 0.0043 14.6 1.2 1.0 1 0 0 1 1 1 1 Prominin EzrA PF06160.7 EPR79115.1 - 0.015 13.5 3.3 0.019 13.1 2.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Mnd1 PF03962.10 EPR79115.1 - 0.023 14.3 1.5 0.026 14.2 1.0 1.0 1 0 0 1 1 1 0 Mnd1 family DUF1002 PF06207.6 EPR79115.1 - 0.032 13.5 2.1 0.038 13.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) TMPIT PF07851.8 EPR79115.1 - 0.041 12.9 0.4 0.047 12.7 0.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein LRRC37AB_C PF14914.1 EPR79115.1 - 0.042 13.2 1.6 0.044 13.2 1.1 1.0 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Fib_alpha PF08702.5 EPR79115.1 - 0.045 13.8 2.5 0.051 13.7 1.7 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF912 PF06024.7 EPR79115.1 - 0.051 13.6 4.7 0.071 13.1 3.2 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFR_dimer PF04253.10 EPR79115.1 - 0.057 12.9 0.3 0.11 12.1 0.2 1.5 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain Vma12 PF11712.3 EPR79115.1 - 0.061 13.0 0.3 0.069 12.8 0.2 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Bacillus_HBL PF05791.6 EPR79115.1 - 0.07 12.4 3.7 0.078 12.3 2.6 1.0 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Plasmid_RAQPRD PF09686.5 EPR79115.1 - 0.083 12.9 0.2 0.12 12.4 0.1 1.3 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Rifin_STEVOR PF02009.11 EPR79115.1 - 0.084 12.5 2.6 0.12 11.9 1.8 1.4 1 1 0 1 1 1 0 Rifin/stevor family Syntaxin-6_N PF09177.6 EPR79115.1 - 0.089 13.1 1.7 0.22 11.9 0.7 1.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lipoprotein_3 PF00938.12 EPR79115.1 - 0.1 12.4 0.8 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 Lipoprotein Baculo_PEP_C PF04513.7 EPR79115.1 - 0.11 12.3 1.6 0.14 11.9 1.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoL PF05461.6 EPR79115.1 - 0.15 11.3 0.5 0.23 10.7 0.3 1.3 1 1 0 1 1 1 0 Apolipoprotein L Syntaxin PF00804.20 EPR79115.1 - 0.18 11.9 5.3 0.3 11.2 3.7 1.5 1 1 0 1 1 1 0 Syntaxin TMF_DNA_bd PF12329.3 EPR79115.1 - 0.21 11.4 3.7 0.28 11.0 2.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding YtxH PF12732.2 EPR79115.1 - 0.31 11.4 1.4 0.43 10.9 1.0 1.3 1 0 0 1 1 1 0 YtxH-like protein FlaC_arch PF05377.6 EPR79115.1 - 0.69 9.8 3.0 8.5 6.3 2.1 2.3 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) ISG65-75 PF11727.3 EPR79115.1 - 0.87 8.5 3.5 0.99 8.3 2.4 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein ETRAMP PF09716.5 EPR79116.1 - 0.016 15.1 5.9 0.016 15.1 4.1 2.9 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) NDK PF00334.14 EPR79118.1 - 1.6e-49 167.1 0.0 1.9e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GCS PF03074.11 EPR79119.1 - 1e-102 344.0 13.8 1.9e-52 178.5 6.6 2.6 1 1 2 3 3 3 2 Glutamate-cysteine ligase DEAD PF00270.24 EPR79121.1 - 6.3e-31 107.1 0.0 2.8e-30 105.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79121.1 - 1.4e-22 79.3 0.0 2.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79121.1 - 0.00025 20.9 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPR79121.1 - 0.0036 17.0 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Helicase_C_2 PF13307.1 EPR79121.1 - 0.0044 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain Ribosomal_L16 PF00252.13 EPR79122.1 - 1.1e-28 99.6 0.1 1.5e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Reo_sigmaC PF04582.7 EPR79124.1 - 0.61 9.2 7.4 1.3 8.1 2.9 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GWT1 PF06423.7 EPR79126.1 - 2.2e-17 63.3 11.0 2.2e-17 63.3 7.6 3.0 2 1 1 3 3 3 1 GWT1 DUF4526 PF15029.1 EPR79126.1 - 0.38 10.2 1.5 0.72 9.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4526) RNA_pol_Rpb4 PF03874.11 EPR79128.1 - 8.9e-10 38.6 5.9 4.1e-09 36.4 4.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 NOG1 PF06858.9 EPR79129.1 - 7.3e-24 83.4 1.7 1.2e-23 82.7 0.2 2.2 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EPR79129.1 - 1.3e-17 63.7 0.1 7.8e-17 61.3 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase NOGCT PF08155.6 EPR79129.1 - 4.7e-14 51.8 3.2 1.2e-13 50.5 2.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.13 EPR79129.1 - 4e-09 35.9 0.1 8.8e-09 34.8 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 EPR79129.1 - 1.9e-06 27.3 0.1 4.6e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR79129.1 - 0.0041 17.6 0.6 0.021 15.2 0.0 2.5 3 1 1 4 4 4 1 Miro-like protein DUF258 PF03193.11 EPR79129.1 - 0.0049 16.0 0.0 0.028 13.6 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPR79129.1 - 0.4 10.4 0.0 0.4 10.4 0.0 3.6 2 2 1 3 3 3 0 Dynamin family AAA_17 PF13207.1 EPR79129.1 - 2.2 9.1 6.3 9.6 7.0 2.0 3.4 2 2 1 3 3 3 0 AAA domain Brix PF04427.13 EPR79130.1 - 1.2e-12 47.9 3.6 1.8e-12 47.3 2.5 1.2 1 0 0 1 1 1 1 Brix domain ORC2 PF04084.9 EPR79131.1 - 7.2e-17 61.2 6.0 1.1e-11 44.2 1.0 2.8 2 1 0 2 2 2 2 Origin recognition complex subunit 2 XPG_I PF00867.13 EPR79132.1 - 1.7e-20 72.8 3.6 5e-20 71.3 0.0 3.4 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.12 EPR79132.1 - 2.7e-13 50.0 0.2 2.7e-13 50.0 0.1 2.5 2 1 0 2 2 2 1 XPG N-terminal domain Astro_capsid PF03115.9 EPR79133.1 - 0.55 8.4 1.6 0.96 7.6 1.1 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DEAD PF00270.24 EPR79134.1 - 6.4e-36 123.3 1.3 7.4e-36 123.1 0.4 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79134.1 - 5.5e-23 80.6 0.1 1.3e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EPR79134.1 - 0.027 13.5 0.1 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 EPR79134.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain ResIII PF04851.10 EPR79134.1 - 0.065 13.0 0.7 0.32 10.7 0.5 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF382 PF04037.8 EPR79134.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF382) S4 PF01479.20 EPR79135.1 - 7e-13 47.8 0.2 1.5e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EPR79135.1 - 0.00052 20.3 0.4 0.00096 19.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4_2 PF13275.1 EPR79135.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 S4 domain Ribosomal_L21e PF01157.13 EPR79136.1 - 9.8e-35 118.3 3.4 1.4e-34 117.8 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Cyclin_N PF00134.18 EPR79137.1 - 1.1e-22 79.9 0.6 1.1e-22 79.9 0.4 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain GPI2 PF06432.6 EPR79138.1 - 4.5e-08 32.7 24.5 6.6e-08 32.2 17.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3147 PF11345.3 EPR79138.1 - 0.049 13.6 1.0 0.049 13.6 0.7 3.0 2 2 0 3 3 3 0 Protein of unknown function (DUF3147) Cytidylate_kin PF02224.13 EPR79139.1 - 4.6e-36 123.6 1.0 6e-36 123.2 0.7 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.1 EPR79139.1 - 5.4e-12 46.1 0.3 1.2e-11 45.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EPR79139.1 - 1.2e-09 38.3 1.3 3.4e-09 36.8 0.9 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.1 EPR79139.1 - 2e-09 38.2 0.4 1.7e-08 35.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPR79139.1 - 0.0003 20.6 0.0 0.00055 19.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPR79139.1 - 0.0073 16.4 0.0 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPR79139.1 - 0.0084 16.3 0.1 1.8 8.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EPR79139.1 - 0.012 14.8 0.2 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 EPR79139.1 - 0.029 13.7 0.1 0.45 9.8 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase S1_2 PF13509.1 EPR79139.1 - 0.047 13.6 1.4 15 5.6 0.0 3.2 3 1 1 4 4 4 0 S1 domain RNA_helicase PF00910.17 EPR79139.1 - 0.053 13.6 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EPR79139.1 - 0.058 13.3 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EPR79139.1 - 0.076 12.8 0.0 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_5 PF07728.9 EPR79139.1 - 0.079 12.6 0.1 7.2 6.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EPR79139.1 - 0.1 12.3 2.2 0.21 11.3 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF87 ABC_tran PF00005.22 EPR79139.1 - 0.12 12.7 0.2 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EPR79139.1 - 0.14 11.7 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EPR79139.1 - 0.16 11.7 0.1 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain CTP_transf_2 PF01467.21 EPR79141.1 - 4.5e-18 65.7 0.0 8e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EPR79141.1 - 0.0017 17.9 0.0 0.0045 16.6 0.0 1.7 1 0 0 1 1 1 1 FAD synthetase Methyltransf_11 PF08241.7 EPR79142.1 - 3e-12 46.8 0.1 6.1e-09 36.2 0.0 2.4 1 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EPR79142.1 - 6.7e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPR79142.1 - 2.7e-06 27.0 13.0 0.015 14.9 6.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EPR79142.1 - 9.6e-06 25.9 8.4 0.0024 18.3 5.8 3.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPR79142.1 - 3.3e-05 24.1 0.1 0.00054 20.2 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR79142.1 - 0.0001 22.8 0.7 0.00031 21.2 0.5 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPR79142.1 - 0.00084 18.4 0.0 0.017 14.2 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase CheR PF01739.13 EPR79142.1 - 0.0023 17.2 5.2 0.4 9.9 3.3 2.8 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.7 EPR79142.1 - 0.0034 16.7 0.7 0.012 14.8 0.5 2.0 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DUF59 PF01883.14 EPR79143.1 - 2.5e-06 27.4 0.0 1.2e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF59 UQ_con PF00179.21 EPR79144.1 - 9.1e-46 154.7 0.3 1e-45 154.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPR79144.1 - 3.2e-05 23.6 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 EPR79144.1 - 0.097 12.1 0.1 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 FH2 PF02181.18 EPR79145.1 - 4.9e-20 71.7 24.3 1.9e-19 69.7 16.9 2.0 1 1 0 1 1 1 1 Formin Homology 2 Domain DUF3531 PF12049.3 EPR79146.1 - 0.0062 16.2 0.4 0.95 9.1 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3531) DUF4070 PF13282.1 EPR79146.1 - 0.031 13.8 0.2 0.084 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) DUF1664 PF07889.7 EPR79146.1 - 5.3 6.8 18.0 1.6 8.5 0.1 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF3573 PF12097.3 EPR79146.1 - 7.2 5.1 10.4 0.57 8.7 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) CPSF_A PF03178.10 EPR79147.1 - 1.7e-10 40.5 7.6 4e-10 39.2 1.2 3.8 3 1 0 3 3 3 1 CPSF A subunit region BBS2_N PF14781.1 EPR79147.1 - 0.019 14.5 1.4 12 5.5 0.1 4.2 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Acyltransferase PF01553.16 EPR79148.1 - 2.1e-20 72.5 0.0 3.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Prolamin_like PF05617.6 EPR79150.1 - 0.039 14.0 1.6 0.063 13.4 0.9 1.5 1 1 0 1 1 1 0 Prolamin-like DUF19 PF01579.13 EPR79150.1 - 0.056 13.4 4.7 0.094 12.6 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF19) B-block_TFIIIC PF04182.7 EPR79151.1 - 6.6e-05 22.6 0.5 6.6e-05 22.6 0.3 3.3 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EPR79151.1 - 0.0054 16.0 2.4 0.024 13.9 0.0 3.1 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding Thiolase_N PF00108.18 EPR79151.1 - 0.04 12.9 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain HTH_27 PF13463.1 EPR79151.1 - 0.093 13.0 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain Pkinase PF00069.20 EPR79152.1 - 2.1e-48 164.7 5.4 1.1e-41 142.6 3.5 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79152.1 - 2.4e-22 79.2 0.8 1.7e-19 69.9 0.4 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EPR79152.1 - 0.0015 17.6 0.1 0.0039 16.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR79152.1 - 0.003 17.3 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPR79152.1 - 0.0086 15.0 0.0 0.02 13.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DNA_pack_N PF02500.10 EPR79153.1 - 0.055 13.0 3.4 0.11 12.0 0.7 2.0 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus Glyco_hydr_30_2 PF14587.1 EPR79153.1 - 0.064 12.1 0.9 0.088 11.7 0.6 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Apc3 PF12895.2 EPR79153.1 - 0.12 12.5 8.6 0.3 11.2 0.3 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin-6_N PF09177.6 EPR79154.1 - 1.7 9.1 5.8 13 6.3 1.7 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 EPR79154.1 - 4 7.4 8.5 4.9 7.1 1.8 2.6 1 1 1 2 2 2 0 bZIP transcription factor E1-E2_ATPase PF00122.15 EPR79155.1 - 1.2e-38 132.4 1.7 1.2e-38 132.4 1.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPR79155.1 - 3e-10 40.8 0.0 4.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EPR79155.1 - 1.6e-06 28.1 0.4 8.4e-06 25.8 0.3 2.4 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.2 EPR79155.1 - 1.6e-06 28.4 0.1 3.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SPC25 PF06703.6 EPR79157.1 - 9.3e-18 64.3 4.9 1.3e-17 63.9 3.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RNA_pol PF00940.14 EPR79157.1 - 0.012 14.1 0.9 0.014 13.8 0.6 1.2 1 0 0 1 1 1 0 DNA-dependent RNA polymerase Nramp PF01566.13 EPR79157.1 - 0.11 11.2 0.2 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein Inos-1-P_synth PF01658.12 EPR79157.1 - 0.63 9.8 11.2 0.087 12.6 2.2 2.5 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase BHD_1 PF10403.4 EPR79158.1 - 2.3e-09 36.6 1.4 6.6e-09 35.1 0.1 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 EPR79158.1 - 0.00018 21.1 0.5 0.0018 17.9 0.0 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 SPC12 PF06645.8 EPR79159.1 - 5.4e-18 64.5 0.1 6.6e-18 64.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Got1 PF04178.7 EPR79159.1 - 0.002 18.2 2.5 0.0032 17.5 1.7 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4257 PF14074.1 EPR79159.1 - 0.073 12.7 0.3 0.098 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) FtsX PF02687.16 EPR79159.1 - 0.51 10.1 5.2 3.8 7.2 4.2 1.7 1 1 0 1 1 1 0 FtsX-like permease family FeoB_C PF07664.7 EPR79159.1 - 7.2 6.1 6.5 2.3 7.7 2.5 1.7 1 1 1 2 2 2 0 Ferrous iron transport protein B C terminus HEAT_2 PF13646.1 EPR79160.1 - 3.8e-09 36.7 0.0 0.0064 16.7 0.0 2.9 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EPR79160.1 - 2.8e-07 30.0 0.0 0.1 12.7 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat DNA_alkylation PF08713.6 EPR79160.1 - 4.6e-06 26.3 0.3 9e-06 25.3 0.1 1.5 1 1 1 2 2 2 1 DNA alkylation repair enzyme HEAT_EZ PF13513.1 EPR79160.1 - 0.059 13.8 0.1 14 6.3 0.0 3.3 3 1 1 4 4 4 0 HEAT-like repeat ELO PF01151.13 EPR79161.1 - 4.2e-52 176.9 31.2 4.8e-52 176.7 21.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family TLC PF03219.9 EPR79162.1 - 2.1e-38 132.0 38.1 4.2e-38 131.0 26.4 1.4 1 1 0 1 1 1 1 TLC ATP/ADP transporter Cytochrom_B558a PF05038.8 EPR79162.1 - 0.2 11.2 0.1 0.2 11.2 0.1 3.3 4 0 0 4 4 4 0 Cytochrome Cytochrome b558 alpha-subunit DUF4233 PF14017.1 EPR79162.1 - 0.45 10.4 0.1 0.45 10.4 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF4233) DUF4448 PF14610.1 EPR79162.1 - 1.3 8.4 3.5 7.3 6.0 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4448) DUF1469 PF07332.6 EPR79162.1 - 4.7 6.9 9.8 2 8.1 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) MFS_1 PF07690.11 EPR79162.1 - 7.8 5.1 35.8 0.021 13.5 5.2 3.9 2 1 2 4 4 4 0 Major Facilitator Superfamily TLC PF03219.9 EPR79163.1 - 5.1e-47 160.4 49.5 2.7e-45 154.7 34.3 2.0 1 1 0 1 1 1 1 TLC ATP/ADP transporter TLC PF03219.9 EPR79164.1 - 7.3e-55 186.3 37.2 1.2e-53 182.3 25.8 1.9 1 1 0 1 1 1 1 TLC ATP/ADP transporter Phage_Gp14 PF10666.4 EPR79165.1 - 0.94 9.3 5.8 0.38 10.6 1.2 2.3 2 1 0 2 2 2 0 Phage protein Gp14 FYRN PF05964.9 EPR79165.1 - 1.5 8.3 4.8 4 6.9 2.6 2.3 2 1 0 2 2 2 0 F/Y-rich N-terminus Arm PF00514.18 EPR79166.1 - 1.1e-35 120.2 5.2 1.4e-09 37.4 0.0 8.2 7 1 0 7 7 7 5 Armadillo/beta-catenin-like repeat IBB PF01749.15 EPR79166.1 - 4.3e-07 30.0 8.2 9e-07 28.9 5.7 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EPR79166.1 - 1.2e-06 28.8 1.0 0.0023 18.3 0.1 4.6 5 3 1 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.1 EPR79166.1 - 8.4e-06 25.9 0.0 0.0099 16.1 0.0 4.1 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.17 EPR79166.1 - 0.023 14.7 0.4 31 4.9 0.0 4.2 2 1 0 2 2 2 0 HEAT repeat 4HBT_3 PF13622.1 EPR79167.1 - 1.6e-18 67.3 0.0 5.4e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EPR79167.1 - 1.7e-07 30.9 0.0 0.00077 19.0 0.0 2.4 2 1 0 2 2 2 2 Acyl-CoA thioesterase Adap_comp_sub PF00928.16 EPR79168.1 - 0.0018 17.4 6.1 0.0066 15.5 4.2 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family COQ7 PF03232.8 EPR79169.1 - 0.097 12.1 0.4 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF2392 PF10288.4 EPR79169.1 - 1.2 9.5 6.2 6 7.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) Imm3 PF14425.1 EPR79169.1 - 1.2 9.1 7.9 0.34 10.8 1.5 2.5 1 1 2 3 3 3 0 Immunity protein Imm3 IPK PF03770.11 EPR79169.1 - 1.9 8.0 6.6 1.6 8.3 0.5 2.1 1 1 0 2 2 2 0 Inositol polyphosphate kinase IL2 PF00715.12 EPR79170.1 - 0.013 15.2 0.2 0.37 10.4 0.0 2.7 2 0 0 2 2 2 0 Interleukin 2 CDC37_N PF03234.9 EPR79171.1 - 3.5e-09 37.2 17.8 9.6e-09 35.7 12.3 1.8 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding SAP18 PF06487.7 EPR79171.1 - 0.058 13.2 1.0 0.15 11.8 0.5 2.0 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Atg14 PF10186.4 EPR79171.1 - 0.11 11.4 8.3 0.16 10.8 5.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AIF_C PF14721.1 EPR79171.1 - 8.1 6.7 11.0 0.72 10.1 3.7 2.0 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF572 PF04502.8 EPR79172.1 - 1e-30 107.1 12.1 1.3e-30 106.7 8.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zinc_ribbon_5 PF13719.1 EPR79172.1 - 0.04 13.5 0.2 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPR79172.1 - 0.057 13.1 0.3 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain E6 PF00518.12 EPR79172.1 - 0.17 12.2 3.4 3 8.1 1.3 2.6 1 1 1 3 3 3 0 Early Protein (E6) zf-RING_2 PF13639.1 EPR79173.1 - 1.3e-14 53.7 5.8 2.2e-14 53.0 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPR79173.1 - 2.8e-08 33.7 2.1 7.2e-08 32.4 1.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPR79173.1 - 5.2e-08 32.7 6.5 9.2e-08 31.9 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR79173.1 - 1.2e-07 31.2 4.3 1.9e-07 30.6 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR79173.1 - 1.6e-07 30.9 4.7 2.6e-07 30.2 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPR79173.1 - 2.3e-07 30.3 6.6 5e-07 29.2 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPR79173.1 - 6.5e-05 22.6 2.3 0.00016 21.4 1.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPR79173.1 - 0.0035 17.3 5.0 0.0068 16.4 3.5 1.5 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.24 EPR79173.1 - 0.0035 16.9 5.6 0.006 16.2 3.9 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EPR79173.1 - 0.038 13.7 3.0 0.22 11.2 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EPR79173.1 - 0.085 12.8 2.4 0.18 11.7 1.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EPR79173.1 - 0.34 10.4 3.1 0.97 9.0 2.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EPR79173.1 - 0.35 10.8 8.8 14 5.7 6.1 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EPR79173.1 - 0.42 10.3 4.2 1.1 9.0 2.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPR79173.1 - 0.54 9.8 9.6 0.21 11.1 4.9 1.6 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPR79173.1 - 3.3 7.6 6.2 14 5.7 4.0 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 EPR79174.1 - 2.2e-64 217.1 0.0 3.9e-64 216.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79174.1 - 2e-38 131.9 0.0 3.6e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EPR79174.1 - 3.9e-11 42.5 25.3 3.8e-06 26.5 3.6 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EPR79174.1 - 2e-05 24.2 3.9 2e-05 24.2 2.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Kinase-like PF14531.1 EPR79174.1 - 5e-05 22.4 0.0 8.5e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HR1 PF02185.11 EPR79174.1 - 0.0051 16.5 10.3 0.0051 16.5 7.1 3.0 3 0 0 3 3 3 1 Hr1 repeat PHD PF00628.24 EPR79174.1 - 0.014 15.0 22.9 0.03 13.9 4.5 2.6 2 0 0 2 2 2 0 PHD-finger PIG-S PF10510.4 EPR79174.1 - 0.044 12.4 2.5 0.063 11.9 1.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein APH PF01636.18 EPR79174.1 - 0.25 11.0 0.1 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DnaJ PF00226.26 EPR79175.1 - 2.3e-12 46.4 1.9 2.3e-12 46.4 1.3 2.0 2 0 0 2 2 2 1 DnaJ domain CorA PF01544.13 EPR79175.1 - 0.075 12.0 2.2 0.093 11.7 1.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_23 PF13476.1 EPR79175.1 - 1.3 9.2 21.1 1.9 8.7 14.6 1.3 1 0 0 1 1 1 0 AAA domain DUF496 PF04363.7 EPR79175.1 - 2.8 7.7 18.9 5.7 6.8 7.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Ribosomal_S24e PF01282.14 EPR79176.1 - 1.4e-19 69.6 0.1 1.4e-19 69.6 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S24e UBX PF00789.15 EPR79176.1 - 0.019 15.0 0.1 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 UBX domain DUF3919 PF13057.1 EPR79176.1 - 0.082 12.3 2.7 0.1 12.0 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Mnd1 PF03962.10 EPR79177.1 - 1.3e-24 86.9 12.9 2.3e-24 86.0 9.0 1.4 1 1 0 1 1 1 1 Mnd1 family FliJ PF02050.11 EPR79177.1 - 0.24 11.4 6.1 0.41 10.7 4.2 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein ACCA PF03255.9 EPR79177.1 - 0.8 9.2 4.4 1.7 8.1 3.0 1.6 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fib_alpha PF08702.5 EPR79177.1 - 1.6 8.8 10.9 3.2 7.8 7.6 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_HK97_TLTM PF06120.6 EPR79177.1 - 1.8 7.8 10.8 1.7 7.9 6.5 1.5 1 1 1 2 2 2 0 Tail length tape measure protein Syntaxin-6_N PF09177.6 EPR79177.1 - 5.6 7.4 8.7 3.8 7.9 2.4 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Nup54 PF13874.1 EPR79177.1 - 8.3 6.0 10.4 8 6.1 3.7 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CTDII PF01556.13 EPR79178.1 - 3.2e-13 49.3 1.4 8.2e-11 41.6 0.1 3.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPR79178.1 - 3.5e-09 36.5 17.5 7.8e-09 35.4 12.2 1.6 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EPR79178.1 - 1.9e-06 27.5 1.5 7.1e-06 25.6 1.0 2.1 1 1 0 1 1 1 1 DnaJ domain DUF3795 PF12675.2 EPR79178.1 - 2.1 8.5 12.5 10 6.4 5.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) DZR PF12773.2 EPR79178.1 - 5.1 7.0 8.7 14 5.6 0.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1870 PF08965.5 EPR79179.1 - 0.051 13.2 1.1 0.11 12.2 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) Phage_Mu_Gam PF07352.7 EPR79179.1 - 0.076 12.5 5.6 0.023 14.1 1.3 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein BEN PF10523.4 EPR79179.1 - 0.4 10.7 3.7 1.6 8.8 0.0 2.7 2 2 0 2 2 2 0 BEN domain CEP170_C PF15308.1 EPR79179.1 - 0.41 8.8 2.4 0.44 8.7 1.7 1.3 1 0 0 1 1 1 0 CEP170 C-terminus TB2_DP1_HVA22 PF03134.14 EPR79181.1 - 2.6e-19 68.7 3.8 4.6e-19 67.9 2.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Corona_M PF01635.13 EPR79181.1 - 0.65 8.9 5.2 1.1 8.2 3.6 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Sec8_exocyst PF04048.9 EPR79182.1 - 0.097 12.2 1.9 0.2 11.2 0.2 2.2 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain SMC_N PF02463.14 EPR79184.1 - 5.2e-34 117.3 73.5 3.1e-32 111.5 51.0 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPR79184.1 - 6.6e-22 77.7 0.7 2e-21 76.1 0.1 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 EPR79184.1 - 1.7e-06 27.4 0.1 3.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EPR79184.1 - 3.5e-05 23.9 19.5 3.5e-05 23.9 13.5 5.7 1 1 3 4 4 4 2 AAA domain XFP PF03894.10 EPR79184.1 - 0.099 12.2 4.0 4.4 6.8 0.1 2.9 2 0 0 2 2 2 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase LRR_8 PF13855.1 EPR79185.1 - 6.3e-05 22.6 4.9 0.038 13.7 0.1 2.5 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.2 EPR79185.1 - 8.4e-05 22.0 8.5 0.011 15.3 0.1 2.5 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPR79185.1 - 0.0085 16.1 2.2 5.4 7.6 0.0 3.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPR79185.1 - 0.051 13.6 7.4 0.48 10.6 0.1 3.7 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 EPR79185.1 - 0.15 12.1 5.9 4.1 7.7 0.0 3.2 2 1 0 2 2 2 0 Leucine Rich repeat Ribonuc_2-5A PF06479.7 EPR79186.1 - 3.7e-27 94.7 2.7 1.5e-26 92.7 1.9 2.1 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EPR79186.1 - 6.5e-24 84.4 8.2 6.5e-24 84.4 5.7 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79186.1 - 0.0013 17.8 7.9 0.0019 17.2 1.7 3.0 2 2 0 2 2 2 1 Protein tyrosine kinase Apocytochr_F_C PF01333.14 EPR79186.1 - 0.03 14.1 0.6 0.07 12.9 0.4 1.6 1 0 0 1 1 1 0 Apocytochrome F, C-terminal RtcB PF01139.12 EPR79187.1 - 3.5e-114 382.0 0.0 4.5e-114 381.7 0.0 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB RNA_pol_Rpb1_4 PF05000.12 EPR79187.1 - 0.0082 15.8 0.5 0.049 13.3 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 CPSase_L_D2 PF02786.12 EPR79187.1 - 0.54 9.5 6.1 5 6.3 0.2 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GLE1 PF07817.8 EPR79188.1 - 4.1e-07 29.1 14.2 6.8e-06 25.2 0.0 3.5 3 2 0 3 3 3 2 GLE1-like protein adh_short PF00106.20 EPR79189.1 - 1.2e-12 48.0 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPR79189.1 - 8.3e-09 35.5 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPR79189.1 - 4.8e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EPR79189.1 - 0.00017 21.7 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPR79189.1 - 0.00029 20.9 0.0 0.00036 20.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EPR79189.1 - 0.012 15.5 0.1 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Eno-Rase_NADH_b PF12242.3 EPR79189.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EPR79189.1 - 0.021 14.4 0.0 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.14 EPR79189.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RIO1 PF01163.17 EPR79190.1 - 7.3e-36 123.2 2.6 1.3e-35 122.4 1.8 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EPR79190.1 - 0.00027 20.9 0.1 0.00065 19.7 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal Pkinase PF00069.20 EPR79190.1 - 0.00099 18.3 1.5 0.0012 18.0 0.5 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EPR79190.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family HTH_45 PF14947.1 EPR79190.1 - 0.0057 16.4 0.9 0.049 13.4 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix Kdo PF06293.9 EPR79190.1 - 0.018 14.1 0.2 0.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RBD-FIP PF09457.5 EPR79190.1 - 0.043 13.6 0.2 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 FIP domain Phage_Capsid_P3 PF09018.6 EPR79191.1 - 0.049 12.2 0.2 0.068 11.7 0.1 1.1 1 0 0 1 1 1 0 P3 major capsid protein ABC_tran PF00005.22 EPR79193.1 - 1.3e-26 93.4 0.1 1.7e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPR79193.1 - 2.7e-12 47.2 1.2 1.3e-09 38.4 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPR79193.1 - 5e-07 29.3 0.1 6.9e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EPR79193.1 - 1.1e-06 28.0 0.6 4.1e-06 26.1 0.4 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EPR79193.1 - 2.2e-06 26.9 0.0 0.0086 15.1 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 EPR79193.1 - 2.5e-05 24.1 0.1 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 EPR79193.1 - 4.3e-05 24.3 0.1 7.2e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPR79193.1 - 5.3e-05 22.6 0.2 0.00017 21.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EPR79193.1 - 5.8e-05 22.1 0.3 0.00017 20.6 0.0 1.8 1 1 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPR79193.1 - 8.6e-05 22.6 0.3 0.00023 21.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPR79193.1 - 9.6e-05 22.4 0.1 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPR79193.1 - 0.00013 22.3 0.1 0.00019 21.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EPR79193.1 - 0.00025 20.7 0.2 0.027 14.1 0.0 2.4 2 1 0 2 2 2 1 NTPase AAA_14 PF13173.1 EPR79193.1 - 0.0005 19.9 0.3 0.007 16.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPR79193.1 - 0.00055 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain cobW PF02492.14 EPR79193.1 - 0.00074 19.0 0.2 0.00092 18.6 0.1 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EPR79193.1 - 0.00084 18.5 0.3 0.0019 17.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPR79193.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain NACHT PF05729.7 EPR79193.1 - 0.0025 17.5 0.4 0.0051 16.4 0.3 1.5 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 EPR79193.1 - 0.0026 17.4 0.2 0.0064 16.2 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EPR79193.1 - 0.003 17.4 3.1 0.15 11.8 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function DUF87 UPF0079 PF02367.12 EPR79193.1 - 0.0038 16.8 0.2 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EPR79193.1 - 0.0041 17.4 3.8 0.024 14.9 2.6 2.0 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EPR79193.1 - 0.0046 16.8 0.1 0.12 12.2 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Septin PF00735.13 EPR79193.1 - 0.0052 15.8 0.1 0.0076 15.3 0.1 1.2 1 0 0 1 1 1 1 Septin AAA_33 PF13671.1 EPR79193.1 - 0.0056 16.5 0.3 0.0091 15.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPR79193.1 - 0.0099 14.7 0.8 0.028 13.2 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.4 EPR79193.1 - 0.011 15.1 0.2 0.028 13.8 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 EPR79193.1 - 0.012 14.7 0.2 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.10 EPR79193.1 - 0.017 13.8 0.9 0.036 12.7 0.1 1.7 1 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein PIF1 PF05970.9 EPR79193.1 - 0.018 14.0 0.4 0.075 11.9 0.0 1.9 2 0 0 2 2 2 0 PIF1-like helicase AAA_28 PF13521.1 EPR79193.1 - 0.019 14.9 0.5 0.052 13.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPR79193.1 - 0.02 14.4 1.5 0.055 13.0 0.2 2.2 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EPR79193.1 - 0.023 14.9 1.6 0.11 12.6 1.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EPR79193.1 - 0.023 14.6 0.5 0.023 14.6 0.3 2.0 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EPR79193.1 - 0.025 14.1 0.2 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EPR79193.1 - 0.031 14.7 0.2 0.089 13.2 0.1 1.8 1 1 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EPR79193.1 - 0.032 13.7 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pox_A32 PF04665.7 EPR79193.1 - 0.041 13.1 1.9 0.056 12.7 0.1 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 EPR79193.1 - 0.044 13.3 0.3 0.083 12.4 0.2 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Guanylate_kin PF00625.16 EPR79193.1 - 0.046 13.1 0.4 0.11 11.9 0.3 1.7 1 1 0 1 1 1 0 Guanylate kinase Dynamin_N PF00350.18 EPR79193.1 - 0.049 13.4 0.6 0.1 12.4 0.4 1.7 1 1 0 1 1 1 0 Dynamin family Mg_chelatase PF01078.16 EPR79193.1 - 0.05 12.7 0.1 0.24 10.5 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EPR79193.1 - 0.058 12.1 0.4 0.11 11.2 0.3 1.4 1 0 0 1 1 1 0 ArgK protein RecA PF00154.16 EPR79193.1 - 0.063 12.3 0.1 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein IstB_IS21 PF01695.12 EPR79193.1 - 0.086 12.2 0.2 0.23 10.8 0.1 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 EPR79193.1 - 0.1 11.1 0.1 0.19 10.3 0.1 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class RNA_helicase PF00910.17 EPR79193.1 - 0.11 12.6 0.5 0.2 11.8 0.0 1.8 2 1 0 2 2 1 0 RNA helicase CAF1 PF04857.15 EPR79195.1 - 4.2e-55 186.8 3.4 6.4e-55 186.3 2.4 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease ABC_tran PF00005.22 EPR79196.1 - 6.5e-26 91.2 0.0 4.6e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EPR79196.1 - 2.5e-08 34.2 1.4 2.5e-08 34.2 1.0 4.0 4 1 0 4 4 3 1 AAA domain SMC_N PF02463.14 EPR79196.1 - 8.9e-06 25.0 0.1 2.2e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EPR79196.1 - 8.1e-05 21.8 43.7 0.0057 15.7 20.1 2.4 1 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EPR79196.1 - 0.00022 20.6 0.0 0.001 18.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPR79196.1 - 0.00036 20.8 0.1 0.01 16.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPR79196.1 - 0.001 18.5 0.2 0.0023 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EPR79196.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EPR79196.1 - 0.0012 17.9 4.3 0.16 10.9 0.1 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EPR79196.1 - 0.0013 19.5 0.0 0.0031 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC2_membrane PF01061.19 EPR79196.1 - 0.0016 17.6 44.9 0.0051 16.0 21.9 2.5 1 1 1 2 2 2 1 ABC-2 type transporter T2SE PF00437.15 EPR79196.1 - 0.0017 17.3 0.0 0.0041 16.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.14 EPR79196.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EPR79196.1 - 0.0085 16.2 0.2 0.018 15.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EPR79196.1 - 0.012 15.1 0.1 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EPR79196.1 - 0.015 15.7 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 EPR79196.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EPR79196.1 - 0.025 14.3 0.2 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EPR79196.1 - 0.035 13.8 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 EPR79196.1 - 0.047 13.2 0.5 0.09 12.3 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPR79196.1 - 0.057 13.0 0.4 0.21 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPR79196.1 - 0.065 12.9 0.2 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 EPR79196.1 - 0.067 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EPR79196.1 - 0.077 12.4 0.5 0.13 11.6 0.4 1.3 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EPR79196.1 - 0.083 12.3 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EPR79196.1 - 0.096 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EPR79196.1 - 0.1 12.8 0.1 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPR79196.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EPR79196.1 - 0.15 12.0 0.1 0.99 9.3 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.16 EPR79196.1 - 0.21 10.7 0.5 1.2 8.2 0.2 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EPR79196.1 - 0.26 11.5 3.1 0.76 10.0 2.1 2.0 1 1 0 1 1 1 0 AAA domain Zip PF02535.17 EPR79197.1 - 0.099 11.6 0.9 0.098 11.6 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FCP1_C PF09309.5 EPR79197.1 - 0.1 11.8 13.1 0.11 11.7 9.1 1.0 1 0 0 1 1 1 0 FCP1, C-terminal PBP_sp32 PF07222.7 EPR79197.1 - 0.1 11.7 8.1 0.11 11.7 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Vfa1 PF08432.5 EPR79197.1 - 0.18 11.8 23.5 0.21 11.5 16.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 EPR79197.1 - 0.18 11.6 2.8 0.21 11.4 1.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 EPR79197.1 - 0.28 8.8 9.8 0.28 8.8 6.8 1.0 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 EPR79197.1 - 0.42 10.0 13.5 0.45 10.0 9.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 BLVR PF06375.6 EPR79197.1 - 0.49 10.1 21.0 0.56 10.0 14.5 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CobT PF06213.7 EPR79197.1 - 0.61 9.1 12.9 0.65 9.0 8.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HCV_NS5a_C PF12941.2 EPR79197.1 - 0.75 9.3 4.5 0.92 9.0 3.1 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region BTV_NS2 PF04514.7 EPR79197.1 - 0.97 8.2 13.2 1 8.1 9.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 EPR79197.1 - 1.6 7.4 18.1 1.8 7.2 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3573 PF12097.3 EPR79197.1 - 1.7 7.1 4.2 1.7 7.1 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RR_TM4-6 PF06459.7 EPR79197.1 - 1.7 8.4 14.8 1.9 8.3 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EPR79197.1 - 2.2 8.0 11.1 2.4 7.8 7.7 1.1 1 0 0 1 1 1 0 DDHD domain SspB PF04386.8 EPR79197.1 - 2.7 7.6 8.9 3.6 7.1 6.2 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RP-C_C PF11800.3 EPR79197.1 - 3.5 7.2 10.5 3.8 7.1 7.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region tRNA_synt_1c_R2 PF04557.10 EPR79197.1 - 4.4 8.0 20.3 3.9 8.2 13.0 1.7 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CDC45 PF02724.9 EPR79197.1 - 4.8 5.1 14.0 5 5.0 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EPR79197.1 - 6.2 6.4 9.6 7.7 6.1 6.6 1.3 1 0 0 1 1 1 0 FAM176 family Cytomega_UL84 PF06284.6 EPR79197.1 - 8.4 4.6 6.5 9.6 4.4 4.5 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Pep3_Vps18 PF05131.9 EPR79198.1 - 0.19 11.1 3.0 0.25 10.7 0.2 2.2 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family Myb_DNA-binding PF00249.26 EPR79199.1 - 5e-26 90.4 7.5 2.4e-14 53.1 0.7 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPR79199.1 - 1.2e-22 79.7 3.6 2.3e-15 56.4 0.0 3.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EPR79199.1 - 0.0085 15.9 0.8 0.026 14.4 0.1 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1013 PF06242.6 EPR79199.1 - 0.095 12.6 2.0 7.4 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) MADF_DNA_bdg PF10545.4 EPR79199.1 - 0.2 11.8 5.4 8.4 6.6 0.0 3.3 2 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PCI PF01399.22 EPR79202.1 - 2.5e-08 34.1 0.4 7.2e-08 32.6 0.3 1.8 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EPR79202.1 - 0.02 14.7 0.8 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPR79202.1 - 0.18 11.4 1.7 2.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC PF00098.18 EPR79203.1 - 5.6e-09 35.5 22.1 0.00053 19.7 1.0 4.8 5 0 0 5 5 5 4 Zinc knuckle SAND PF01342.16 EPR79203.1 - 0.001 18.7 1.7 0.001 18.7 1.2 2.3 2 0 0 2 2 2 1 SAND domain zf-CCHC_2 PF13696.1 EPR79203.1 - 0.042 13.3 0.2 0.042 13.3 0.1 3.7 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 EPR79203.1 - 3 7.5 32.1 0.57 9.8 1.2 4.9 3 1 2 5 5 5 0 Zinc knuckle DUF1002 PF06207.6 EPR79204.1 - 0.015 14.5 4.2 0.016 14.5 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Adaptin_N PF01602.15 EPR79204.1 - 0.079 11.2 4.3 0.082 11.2 3.0 1.0 1 0 0 1 1 1 0 Adaptin N terminal region CUE PF02845.11 EPR79204.1 - 0.14 11.6 0.6 0.23 10.9 0.4 1.4 1 0 0 1 1 1 0 CUE domain EF-hand_7 PF13499.1 EPR79205.1 - 3.7e-11 42.9 7.8 9.1e-05 22.5 0.0 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EPR79205.1 - 4.1e-11 41.3 2.3 0.00092 18.3 0.0 4.5 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EPR79205.1 - 5.6e-09 35.1 4.8 0.41 10.6 0.5 4.8 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EPR79205.1 - 9.3e-07 28.3 0.7 0.041 13.5 0.0 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EPR79205.1 - 2.4e-05 23.4 0.3 0.2 11.0 0.0 3.3 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 EPR79205.1 - 0.0088 15.7 0.7 0.075 12.7 0.1 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand S10_plectin PF03501.10 EPR79205.1 - 0.04 13.7 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain NIF3 PF01784.13 EPR79206.1 - 1.1e-41 142.9 0.1 1.5e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Glyphos_transf PF04464.9 EPR79206.1 - 0.034 12.8 1.9 0.049 12.3 0.1 1.9 2 1 0 2 2 2 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 7tm_6 PF02949.15 EPR79207.1 - 0.019 13.8 3.4 0.042 12.7 1.3 2.2 2 1 0 2 2 2 0 7tm Odorant receptor RRN3 PF05327.6 EPR79207.1 - 0.046 11.8 28.7 12 3.8 0.3 4.5 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FSIP1 PF15554.1 EPR79207.1 - 0.51 9.1 8.6 0.21 10.3 2.8 1.9 2 0 0 2 2 2 0 FSIP1 family Ran_BP1 PF00638.13 EPR79208.1 - 1.2e-08 35.0 0.4 2.2e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain Afaf PF15339.1 EPR79208.1 - 0.5 9.9 5.9 0.86 9.1 4.1 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor LsmAD PF06741.8 EPR79209.1 - 2.1e-18 66.1 1.2 2.1e-18 66.1 0.8 4.1 2 1 3 5 5 5 1 LsmAD domain Ufd2P_core PF10408.4 EPR79210.1 - 1.4e-21 76.3 3.4 1.8e-21 76.0 2.4 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EPR79210.1 - 3.6e-17 62.0 0.3 7.5e-17 61.0 0.2 1.6 1 0 0 1 1 1 1 U-box domain Metallophos PF00149.23 EPR79211.1 - 2.9e-23 82.3 1.7 5.2e-23 81.5 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_8 PF13181.1 EPR79211.1 - 0.0056 16.3 2.7 0.1 12.3 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPR79211.1 - 0.012 15.5 0.3 0.18 11.7 0.6 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPR79211.1 - 0.024 14.5 0.9 0.34 10.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPR79211.1 - 0.032 14.1 0.4 0.032 14.1 0.3 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Ufd2P_core PF10408.4 EPR79212.1 - 1e-29 103.3 32.9 1.3e-14 53.3 12.0 3.1 1 1 1 2 2 2 2 Ubiquitin elongating factor core Actin PF00022.14 EPR79213.1 - 4.1e-08 32.0 1.4 1.2e-07 30.5 0.8 2.1 2 0 0 2 2 2 1 Actin LcrV PF04792.7 EPR79214.1 - 0.089 11.8 2.1 0.097 11.6 1.4 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein DUF4313 PF14190.1 EPR79214.1 - 0.15 11.7 1.8 0.25 11.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) DUF663 PF04950.7 EPR79216.1 - 1.1e-39 136.2 6.3 1.1e-39 136.2 4.4 4.3 1 1 2 4 4 4 1 Protein of unknown function (DUF663) GTP_EFTU PF00009.22 EPR79216.1 - 3.1e-08 33.2 6.9 6.7e-07 28.9 0.7 3.9 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPR79216.1 - 0.0021 18.0 0.6 0.0021 18.0 0.4 3.4 3 2 0 3 3 3 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EPR79216.1 - 0.0022 17.9 0.7 0.0022 17.9 0.5 4.2 3 2 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPR79216.1 - 0.059 13.5 0.2 0.54 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPR79216.1 - 0.12 12.6 0.0 0.12 12.6 0.0 4.0 3 1 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 EPR79216.1 - 0.17 11.8 0.0 0.86 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EPR79216.1 - 0.59 10.9 0.0 0.59 10.9 0.0 4.2 3 2 1 4 4 4 0 AAA domain DUF4539 PF15072.1 EPR79217.1 - 0.0022 17.6 2.7 0.0027 17.3 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) HlyD_2 PF12700.2 EPR79217.1 - 0.035 13.2 9.4 0.048 12.8 6.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Yos1 PF08571.5 EPR79218.1 - 1.8e-19 69.5 2.3 2.1e-19 69.3 1.6 1.0 1 0 0 1 1 1 1 Yos1-like TBPIP PF07106.8 EPR79219.1 - 0.0015 18.0 8.9 0.0018 17.8 5.9 1.3 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF869 PF05911.6 EPR79219.1 - 0.0021 16.3 4.2 0.0024 16.1 2.9 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) NPV_P10 PF05531.7 EPR79219.1 - 0.0024 18.1 12.3 0.0029 17.7 7.9 1.7 1 1 0 1 1 1 1 Nucleopolyhedrovirus P10 protein HOOK PF05622.7 EPR79219.1 - 0.0024 15.7 5.8 0.0027 15.6 4.0 1.0 1 0 0 1 1 1 1 HOOK protein Tropomyosin PF00261.15 EPR79219.1 - 0.0029 16.7 1.2 0.0037 16.3 0.8 1.2 1 0 0 1 1 1 1 Tropomyosin MscS_porin PF12795.2 EPR79219.1 - 0.0079 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Nsp1_C PF05064.8 EPR79219.1 - 0.0083 15.7 3.9 0.0083 15.7 2.7 1.5 2 0 0 2 2 1 1 Nsp1-like C-terminal region DUF1395 PF07160.7 EPR79219.1 - 0.0096 15.4 4.5 0.0095 15.4 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) RmuC PF02646.11 EPR79219.1 - 0.011 14.5 2.8 0.014 14.2 1.6 1.4 1 1 0 1 1 1 0 RmuC family Spc7 PF08317.6 EPR79219.1 - 0.017 13.7 8.5 0.021 13.5 5.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.6 EPR79219.1 - 0.018 14.8 1.0 0.031 14.1 0.7 1.6 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3552 PF12072.3 EPR79219.1 - 0.021 14.0 3.4 0.028 13.6 2.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) ADIP PF11559.3 EPR79219.1 - 0.024 14.5 7.4 0.032 14.1 5.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V-SNARE PF05008.10 EPR79219.1 - 0.032 14.3 2.1 0.032 14.3 1.4 1.7 2 0 0 2 2 1 0 Vesicle transport v-SNARE protein N-terminus DUF489 PF04356.7 EPR79219.1 - 0.041 13.4 1.8 0.056 13.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Fib_alpha PF08702.5 EPR79219.1 - 0.042 13.9 10.4 0.062 13.4 7.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WEMBL PF05701.6 EPR79219.1 - 0.048 12.1 2.7 0.051 12.0 1.9 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF2360 PF10152.4 EPR79219.1 - 0.052 13.8 0.4 0.13 12.5 0.2 1.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) V_ATPase_I PF01496.14 EPR79219.1 - 0.061 11.1 4.8 0.07 10.9 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-SNARE_C PF12352.3 EPR79219.1 - 0.073 13.1 8.3 0.94 9.6 1.0 3.2 2 1 2 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 EPR79219.1 - 0.076 12.7 10.4 0.11 12.2 7.2 1.4 1 1 0 1 1 1 0 Laminin Domain II Reo_sigmaC PF04582.7 EPR79219.1 - 0.08 12.1 2.0 0.086 12.0 1.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EPR79219.1 - 0.09 12.5 5.4 0.067 12.9 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Flu_NS2 PF00601.14 EPR79219.1 - 0.092 12.9 1.8 0.68 10.1 1.3 2.2 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) Baculo_PEP_C PF04513.7 EPR79219.1 - 0.1 12.3 14.1 0.14 12.0 9.8 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EPR79219.1 - 0.12 12.1 5.0 0.16 11.7 3.5 1.3 1 1 0 1 1 1 0 Tropomyosin like WXG100 PF06013.7 EPR79219.1 - 0.13 12.2 0.3 0.96 9.4 0.1 2.0 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Minor_capsid_3 PF12691.2 EPR79219.1 - 0.2 11.3 8.3 3.2 7.4 0.3 2.3 1 1 1 2 2 2 0 Minor capsid protein from bacteriophage Allexi_40kDa PF05549.6 EPR79219.1 - 0.21 10.8 5.8 0.24 10.6 4.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Sec34 PF04136.10 EPR79219.1 - 0.24 11.0 6.2 0.77 9.4 1.0 2.0 1 1 1 2 2 2 0 Sec34-like family TMF_DNA_bd PF12329.3 EPR79219.1 - 0.24 11.2 5.6 4 7.3 0.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EPR79219.1 - 0.25 11.0 12.9 0.53 9.9 8.9 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 L31 PF09784.4 EPR79219.1 - 0.3 11.1 2.6 0.67 10.0 1.8 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 Alpha-2-MRAP_C PF06401.6 EPR79219.1 - 0.31 10.8 7.8 0.62 9.8 5.4 1.4 1 1 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain APG6 PF04111.7 EPR79219.1 - 0.52 9.3 7.6 0.64 9.0 5.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Noelin-1 PF12308.3 EPR79219.1 - 0.67 9.7 4.4 0.43 10.4 1.8 1.6 2 0 0 2 2 1 0 Neurogenesis glycoprotein EMP24_GP25L PF01105.19 EPR79219.1 - 0.8 9.3 6.0 1.7 8.2 1.4 2.5 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD Matrilin_ccoil PF10393.4 EPR79219.1 - 0.85 9.0 5.5 7.9 5.9 0.2 2.6 2 1 1 3 3 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Snapin_Pallidin PF14712.1 EPR79219.1 - 1 9.7 8.1 2.9 8.2 3.8 2.6 1 1 1 2 2 2 0 Snapin/Pallidin DUF211 PF02680.9 EPR79219.1 - 1 9.2 7.6 0.13 12.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 Flagellin_C PF00700.16 EPR79219.1 - 1.6 8.8 5.6 4.4 7.5 3.9 1.9 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region FlaC_arch PF05377.6 EPR79219.1 - 3.1 7.7 13.5 0.86 9.5 2.7 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2981 PF11200.3 EPR79219.1 - 5.7 5.9 17.0 1.7 7.6 8.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) MutS_V PF00488.16 EPR79222.1 - 2e-29 102.6 2.7 1.3e-26 93.4 0.2 2.5 1 1 0 2 2 2 2 MutS domain V AAA_29 PF13555.1 EPR79222.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EPR79222.1 - 3.4 8.5 8.0 2.8 8.7 0.3 3.8 2 2 0 2 2 2 0 AAA domain Ribosomal_L39 PF00832.15 EPR79223.1 - 3.4e-10 39.2 2.5 4.7e-10 38.7 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein Histone PF00125.19 EPR79224.1 - 2.2e-26 91.7 0.1 3.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPR79224.1 - 0.00056 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPR79224.1 - 0.0053 16.9 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S SH3_2 PF07653.12 EPR79224.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Histone PF00125.19 EPR79225.1 - 5.3e-10 39.2 0.1 6.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPR79225.1 - 1.4e-05 25.0 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EPR79225.1 - 5.3e-05 23.0 0.0 7.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EPR79225.1 - 9.7e-05 22.4 0.0 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EPR79225.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EPR79225.1 - 0.084 12.6 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit E3_binding PF02817.12 EPR79225.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 e3 binding domain TFIID-18kDa PF02269.11 EPR79225.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CH PF00307.26 EPR79227.1 - 2.3e-30 104.8 10.2 2.3e-18 66.2 0.1 3.6 3 1 1 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EPR79227.1 - 1.2e-08 34.4 2.0 1.2e-07 31.2 0.0 3.3 3 1 0 3 3 3 1 CAMSAP CH domain EF-hand_7 PF13499.1 EPR79227.1 - 1e-07 31.9 2.3 4.5e-05 23.4 0.4 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EPR79227.1 - 1e-05 24.4 3.5 0.001 18.2 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EPR79227.1 - 0.00011 21.8 0.1 0.0032 17.2 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EPR79227.1 - 0.011 15.2 1.0 0.19 11.3 0.0 3.6 5 0 0 5 5 5 0 EF-hand domain pair tRNA-synt_1g PF09334.6 EPR79230.1 - 1.7e-122 408.9 4.6 2.2e-122 408.5 3.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPR79230.1 - 3.9e-07 28.4 2.1 0.00049 18.2 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Laminin_EGF PF00053.19 EPR79230.1 - 0.32 10.9 8.8 0.79 9.6 6.1 1.7 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Rcd1 PF04078.8 EPR79231.1 - 2.2e-50 170.9 2.2 2.4e-50 170.8 1.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like LRR_8 PF13855.1 EPR79232.1 - 1.3e-05 24.8 3.5 2.6e-05 23.8 1.8 2.1 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 EPR79232.1 - 0.0058 16.2 2.1 0.0058 16.2 1.5 4.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79232.1 - 0.026 14.5 4.6 0.94 9.7 0.1 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat Imm-NTF2-2 PF15631.1 EPR79232.1 - 0.081 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NTF2 fold immunity protein LRR_4 PF12799.2 EPR79234.1 - 1e-23 82.4 47.0 2.1e-07 30.3 2.7 5.9 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79234.1 - 8.6e-23 79.8 39.2 2.4e-07 30.4 2.5 5.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EPR79234.1 - 4.3e-16 56.4 47.8 0.023 14.6 0.2 10.4 9 2 1 10 10 10 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR79234.1 - 2.5e-12 44.8 27.4 0.33 11.3 0.0 10.0 10 0 0 10 10 10 5 Leucine rich repeat LRR_6 PF13516.1 EPR79234.1 - 1.1e-05 25.0 46.7 0.085 12.9 0.2 9.8 10 1 1 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 EPR79234.1 - 5.4 6.5 9.0 0.8 9.2 0.1 3.1 2 2 1 3 3 3 0 Leucine-rich repeat Swi5 PF07061.6 EPR79235.1 - 2.8e-17 62.2 4.2 3.1e-17 62.1 2.9 1.2 1 0 0 1 1 1 1 Swi5 DUF4494 PF14902.1 EPR79235.1 - 0.0017 17.9 3.0 0.0021 17.6 1.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4494) DUF4145 PF13643.1 EPR79235.1 - 0.017 14.9 0.3 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) DUF966 PF06136.8 EPR79235.1 - 0.039 13.3 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2972 PF11186.3 EPR79235.1 - 0.039 13.8 8.4 0.051 13.4 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) XH PF03469.9 EPR79235.1 - 0.16 11.5 1.8 0.2 11.3 1.2 1.3 1 0 0 1 1 1 0 XH domain DUF2951 PF11166.3 EPR79235.1 - 0.22 11.4 4.9 0.25 11.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF768 PF05589.6 EPR79235.1 - 0.42 10.5 2.5 0.4 10.6 0.4 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF768) PI3K_p85B PF02192.11 EPR79235.1 - 0.47 9.9 2.4 0.5 9.8 0.2 2.0 1 1 1 2 2 2 0 PI3-kinase family, p85-binding domain Seadorna_VP6 PF07407.6 EPR79235.1 - 0.83 8.3 4.9 0.85 8.3 3.4 1.0 1 0 0 1 1 1 0 Seadornavirus VP6 protein Ribosomal_S17 PF00366.15 EPR79236.1 - 1.3e-22 79.6 2.3 2.5e-22 78.6 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 UQ_con PF00179.21 EPR79237.1 - 1.4e-42 144.4 0.2 1.6e-42 144.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPR79237.1 - 0.0062 16.4 0.2 0.0092 15.8 0.1 1.5 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EPR79238.1 - 4.7e-13 48.7 5.7 4.7e-13 48.7 4.0 2.1 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 EPR79238.1 - 1.4e-08 34.2 6.1 1.4e-08 34.2 4.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPR79238.1 - 1.8e-08 34.3 5.0 1.8e-08 34.3 3.5 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPR79238.1 - 3.4e-08 33.3 7.1 3.4e-08 33.3 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR79238.1 - 1.1e-06 28.1 4.0 1.1e-06 28.1 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR79238.1 - 1.4e-06 27.8 7.9 1.4e-06 27.8 5.5 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Cytomega_TRL10 PF06084.6 EPR79238.1 - 0.00011 22.0 0.4 0.00018 21.3 0.3 1.4 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein FANCL_C PF11793.3 EPR79238.1 - 0.003 17.4 3.6 0.003 17.4 2.5 2.5 1 1 1 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EPR79238.1 - 0.0059 16.4 5.2 0.023 14.5 3.6 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPR79238.1 - 0.024 14.6 3.9 0.024 14.6 2.7 2.2 2 1 0 2 2 2 0 RING-variant domain zf-RING_6 PF14835.1 EPR79238.1 - 0.072 12.8 0.8 0.18 11.5 0.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein SapB_1 PF05184.10 EPR79238.1 - 0.1 12.4 0.4 0.1 12.4 0.3 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 zf-RING_UBOX PF13445.1 EPR79238.1 - 0.12 12.1 2.9 0.41 10.3 2.1 1.9 1 1 1 2 2 2 0 RING-type zinc-finger MMgT PF10270.4 EPR79238.1 - 0.14 12.5 3.3 0.63 10.4 0.1 2.4 2 1 0 2 2 2 0 Membrane magnesium transporter zf-CCHC_5 PF14787.1 EPR79238.1 - 0.44 10.0 10.8 0.15 11.5 3.0 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-C3HC4_4 PF15227.1 EPR79238.1 - 1.4 8.8 5.4 6.7 6.6 3.7 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosomal_L7Ae PF01248.21 EPR79239.1 - 1.1e-24 85.7 0.8 1.4e-24 85.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EPR79239.1 - 0.0055 16.5 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 zf-RING_2 PF13639.1 EPR79241.1 - 1.4e-14 53.6 5.4 2.5e-14 52.8 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPR79241.1 - 1.6e-10 40.9 5.6 3.7e-10 39.7 3.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPR79241.1 - 3e-09 36.7 5.8 8e-09 35.3 4.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR79241.1 - 5e-09 35.6 3.1 9.3e-09 34.8 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR79241.1 - 7e-09 35.2 6.0 1.3e-08 34.3 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR79241.1 - 3.8e-08 32.9 3.4 6.2e-08 32.2 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPR79241.1 - 6.7e-07 29.0 3.4 4.6e-06 26.3 2.4 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EPR79241.1 - 0.012 15.5 6.3 0.012 15.5 4.3 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EPR79241.1 - 0.015 14.8 5.8 0.027 14.0 4.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EPR79241.1 - 0.031 14.3 3.1 0.074 13.1 2.1 1.7 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EPR79241.1 - 0.046 13.4 1.4 0.25 11.0 1.0 2.2 1 1 1 2 2 2 0 RING-type zinc-finger DUF788 PF05620.6 EPR79241.1 - 0.28 11.0 0.1 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) zf-RING-like PF08746.6 EPR79241.1 - 0.29 11.1 6.2 0.087 12.8 2.0 1.8 2 0 0 2 2 2 0 RING-like domain zf-RING_6 PF14835.1 EPR79241.1 - 0.3 10.8 3.7 0.45 10.3 1.1 2.3 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EPR79241.1 - 2.6 8.0 5.8 7 6.6 4.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Sld5 PF05916.6 EPR79242.1 - 0.0098 16.1 0.3 0.013 15.8 0.2 1.4 1 1 0 1 1 1 1 GINS complex protein Hist_deacetyl PF00850.14 EPR79243.1 - 1.2e-80 271.1 0.2 1.6e-80 270.7 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Carb_kinase PF01256.12 EPR79244.1 - 6.4e-34 117.2 0.0 1.6e-32 112.7 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase Kri1_C PF12936.2 EPR79245.1 - 2.4e-06 27.4 9.6 2.4e-06 27.4 6.6 2.9 2 2 0 2 2 2 1 KRI1-like family C-terminal SLY PF12485.3 EPR79245.1 - 3.7 7.7 20.7 0.81 9.9 9.0 2.2 1 1 1 2 2 2 0 Lymphocyte signaling adaptor protein TPR_7 PF13176.1 EPR79246.1 - 0.028 14.2 0.0 13 5.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPR79246.1 - 0.03 14.9 0.0 44 5.1 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPR79246.1 - 0.32 11.0 6.9 54 4.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EPR79247.1 - 0.00019 20.7 3.0 0.00022 20.4 1.4 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79247.1 - 0.034 13.2 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 EPR79247.1 - 0.063 12.3 0.7 0.097 11.7 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.17 EPR79248.1 - 1.2e-52 177.5 2.5 1.4e-52 177.3 1.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR79248.1 - 6.2e-21 75.0 1.4 8.4e-21 74.6 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPR79248.1 - 1.5e-19 69.8 1.9 2.1e-19 69.4 1.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPR79248.1 - 1.5e-10 40.6 0.9 1.9e-10 40.2 0.7 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPR79248.1 - 1.5e-08 34.6 1.0 2.7e-08 33.7 0.7 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPR79248.1 - 5e-08 32.6 1.4 4e-07 29.6 0.9 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPR79248.1 - 2.6e-05 24.3 0.1 0.00021 21.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EPR79248.1 - 9.8e-05 21.6 2.6 0.0004 19.6 1.8 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 EPR79248.1 - 0.00013 22.1 0.1 0.01 16.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPR79248.1 - 0.00077 18.6 0.0 0.0019 17.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EPR79248.1 - 0.0015 17.5 0.1 0.0021 17.1 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain FeoB_N PF02421.13 EPR79248.1 - 0.0016 17.7 1.9 0.0034 16.6 1.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.13 EPR79248.1 - 0.0017 17.4 0.8 0.004 16.1 0.0 1.9 2 0 0 2 2 2 1 Septin AAA_5 PF07728.9 EPR79248.1 - 0.0021 17.7 0.1 0.008 15.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EPR79248.1 - 0.0041 16.8 0.1 0.0041 16.8 0.1 2.0 1 1 1 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EPR79248.1 - 0.0049 16.8 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EPR79248.1 - 0.0064 16.1 1.4 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Chordopox_A30L PF06015.7 EPR79248.1 - 0.011 15.3 2.8 0.011 15.3 2.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A30L protein NTPase_1 PF03266.10 EPR79248.1 - 0.016 14.9 0.6 0.029 14.0 0.4 1.8 1 1 0 1 1 1 0 NTPase AAA_10 PF12846.2 EPR79248.1 - 0.03 13.7 0.0 0.038 13.4 0.0 1.2 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EPR79248.1 - 0.037 14.3 1.8 0.12 12.6 1.2 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EPR79248.1 - 0.059 12.8 0.6 0.11 12.0 0.4 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 EPR79248.1 - 0.084 11.9 3.2 0.4 9.7 2.2 2.2 1 1 0 1 1 1 0 AIG1 family ArgK PF03308.11 EPR79248.1 - 0.11 11.2 0.8 4.2 6.0 0.0 2.1 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 EPR79248.1 - 0.19 11.1 1.1 0.49 9.8 0.8 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPR79248.1 - 0.44 10.4 2.9 0.42 10.5 0.4 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EPR79248.1 - 1.3 9.8 4.8 4 8.2 3.3 2.0 1 1 0 1 1 1 0 AAA domain MerC PF03203.9 EPR79249.1 - 0.0051 17.1 3.2 0.015 15.6 0.1 2.3 2 0 0 2 2 2 1 MerC mercury resistance protein Prefoldin_3 PF13758.1 EPR79249.1 - 0.29 10.9 0.0 0.29 10.9 0.0 4.5 3 1 0 4 4 4 0 Prefoldin subunit Na_Ca_ex PF01699.19 EPR79249.1 - 0.44 10.1 9.1 0.91 9.1 1.4 2.6 2 0 0 2 2 2 0 Sodium/calcium exchanger protein Vac_Fusion PF02346.11 EPR79249.1 - 5 6.6 9.8 8.8 5.8 0.1 4.0 4 0 0 4 4 4 0 Chordopoxvirus fusion protein AAA PF00004.24 EPR79250.1 - 8.9e-57 190.9 0.2 2.1e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPR79250.1 - 1.6e-12 47.4 0.5 5.1e-08 32.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPR79250.1 - 1e-11 45.1 3.9 0.0026 17.9 0.1 4.4 2 2 1 3 3 3 3 AAA domain AAA_17 PF13207.1 EPR79250.1 - 9.9e-10 39.2 0.0 0.0016 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPR79250.1 - 6.7e-09 36.1 0.8 0.0024 18.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EPR79250.1 - 1.8e-08 34.2 0.0 0.0011 18.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPR79250.1 - 5e-08 33.0 0.0 3e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EPR79250.1 - 1.9e-07 30.6 3.8 0.0074 16.0 0.1 2.7 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 EPR79250.1 - 7.1e-07 28.8 0.4 0.0066 15.8 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.8 EPR79250.1 - 7.4e-07 28.2 0.0 0.0054 15.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 EPR79250.1 - 1.2e-06 27.7 0.2 0.0052 15.9 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPR79250.1 - 1.5e-06 28.1 0.0 0.056 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPR79250.1 - 3.4e-06 26.6 0.0 0.024 14.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPR79250.1 - 5.4e-06 26.5 0.1 0.19 11.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain PhoH PF02562.11 EPR79250.1 - 5.7e-06 25.7 0.2 0.042 13.0 0.0 2.7 2 1 1 3 3 3 2 PhoH-like protein RNA_helicase PF00910.17 EPR79250.1 - 3.2e-05 24.0 0.0 0.35 11.0 0.0 3.3 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.7 EPR79250.1 - 3.3e-05 23.0 0.1 0.068 12.2 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 EPR79250.1 - 5.1e-05 22.8 1.1 1 8.8 0.0 4.4 3 1 1 4 4 4 1 DEAD/DEAH box helicase ResIII PF04851.10 EPR79250.1 - 8.6e-05 22.4 0.1 0.14 11.9 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EPR79250.1 - 0.00015 21.7 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EPR79250.1 - 0.00019 20.9 0.0 0.39 10.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain UPF0079 PF02367.12 EPR79250.1 - 0.0002 20.9 0.1 0.092 12.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EPR79250.1 - 0.00028 21.1 0.7 0.041 14.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter T2SE PF00437.15 EPR79250.1 - 0.00055 18.9 0.1 0.12 11.2 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF2075 PF09848.4 EPR79250.1 - 0.00057 18.9 0.0 0.045 12.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EPR79250.1 - 0.00058 19.5 0.1 0.36 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EPR79250.1 - 0.00085 18.2 1.4 0.11 11.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain KaiC PF06745.8 EPR79250.1 - 0.0015 17.7 6.6 0.18 10.8 0.1 3.4 4 0 0 4 4 4 2 KaiC AAA_24 PF13479.1 EPR79250.1 - 0.0035 16.9 0.5 2.5 7.6 0.1 2.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPR79250.1 - 0.0053 16.8 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EPR79250.1 - 0.0085 15.7 0.4 6.1 6.4 0.0 2.9 3 0 0 3 3 3 0 NACHT domain ATP-synt_ab PF00006.20 EPR79250.1 - 0.0091 15.5 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_3 PF07726.6 EPR79250.1 - 0.0093 15.5 0.0 0.24 11.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPR79250.1 - 0.015 14.8 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPR79250.1 - 0.03 13.4 0.0 2.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.17 EPR79250.1 - 0.048 13.5 0.7 6.9 6.5 0.0 3.1 3 1 1 4 4 3 0 Shikimate kinase IPT PF01745.11 EPR79250.1 - 0.086 11.9 0.5 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase MCM PF00493.18 EPR79251.1 - 8.3e-126 419.2 1.0 1.1e-125 418.8 0.7 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPR79251.1 - 4.1e-08 33.7 8.6 2.3e-06 28.0 0.5 4.2 3 2 0 3 3 3 2 MCM N-terminal domain Mg_chelatase PF01078.16 EPR79251.1 - 1.3e-07 30.9 0.0 1.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPR79251.1 - 0.0028 17.2 0.0 0.0063 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPR79251.1 - 0.0036 16.7 0.1 0.023 14.1 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain tRNA_anti-codon PF01336.20 EPR79251.1 - 0.022 14.6 1.0 4.2 7.2 0.0 2.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Miro PF08477.8 EPR79251.1 - 0.062 13.7 2.8 3.8 8.0 0.3 3.1 2 1 0 2 2 2 0 Miro-like protein Macoilin PF09726.4 EPR79252.1 - 0.0077 14.5 10.2 0.013 13.8 7.1 1.3 1 0 0 1 1 1 1 Transmembrane protein DUF573 PF04504.9 EPR79252.1 - 0.087 13.1 0.2 0.087 13.1 0.1 3.8 4 2 1 5 5 5 0 Protein of unknown function, DUF573 DUF1136 PF06582.7 EPR79252.1 - 2.6 7.8 6.0 1 9.1 0.5 2.7 3 0 0 3 3 3 0 Repeat of unknown function (DUF1136) Ras PF00071.17 EPR79253.1 - 3.6e-44 150.0 1.1 4.3e-44 149.7 0.8 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EPR79253.1 - 3.6e-21 75.1 0.8 4.5e-21 74.8 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPR79253.1 - 9.8e-21 74.4 0.8 1.4e-20 73.9 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EPR79253.1 - 3.5e-13 49.2 2.1 4.5e-13 48.8 1.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPR79253.1 - 3.1e-07 30.0 1.7 4.2e-06 26.3 1.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPR79253.1 - 3.8e-07 30.0 1.3 4.5e-07 29.8 0.2 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPR79253.1 - 5.7e-05 22.3 0.4 0.00012 21.4 0.2 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EPR79253.1 - 0.00024 20.9 0.2 0.00089 19.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EPR79253.1 - 0.00029 20.4 0.9 0.003 17.1 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EPR79253.1 - 0.00054 19.4 1.9 0.0029 17.0 1.3 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EPR79253.1 - 0.00086 19.4 0.3 0.011 15.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain MobB PF03205.9 EPR79253.1 - 0.0025 17.5 1.9 0.0035 17.0 0.0 2.1 2 2 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EPR79253.1 - 0.0071 15.6 2.7 0.064 12.5 1.9 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 EPR79253.1 - 0.0081 16.3 0.0 0.037 14.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) VWA_3 PF13768.1 EPR79253.1 - 0.017 14.8 0.1 0.03 14.0 0.0 1.5 2 0 0 2 2 1 0 von Willebrand factor type A domain AAA_33 PF13671.1 EPR79253.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 1 1 2 2 2 0 AAA domain DUF658 PF04936.7 EPR79253.1 - 0.023 14.5 0.8 0.034 14.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) AAA_28 PF13521.1 EPR79253.1 - 0.034 14.0 0.1 0.051 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPR79253.1 - 0.042 13.2 0.0 0.089 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain His_Phos_1 PF00300.17 EPR79253.1 - 0.15 12.1 0.1 4.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) AAA_16 PF13191.1 EPR79253.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EPR79253.1 - 0.15 10.6 5.6 20 3.7 3.8 2.9 1 1 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.18 EPR79253.1 - 0.3 10.8 3.7 1.2 8.9 0.0 2.7 2 1 1 3 3 3 0 Dynamin family TAF4 PF05236.9 EPR79254.1 - 8.6e-31 107.1 6.4 1.2e-30 106.7 4.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family MalF_P2 PF14785.1 EPR79254.1 - 0.15 11.8 1.3 4.8 7.0 0.4 2.2 1 1 1 2 2 2 0 Maltose transport system permease protein MalF P2 domain LMBR1 PF04791.11 EPR79254.1 - 4.2 5.8 7.9 0.98 7.9 2.3 1.8 1 1 0 2 2 2 0 LMBR1-like membrane protein DUF3750 PF12570.3 EPR79255.1 - 0.014 15.6 3.2 0.065 13.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3750) Peptidase_M22 PF00814.20 EPR79256.1 - 1.7e-77 260.5 0.0 2.1e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family SecY PF00344.15 EPR79257.1 - 2.4e-78 263.4 21.0 3e-78 263.1 14.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPR79257.1 - 8.3e-15 54.0 0.1 2e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p CCD PF07860.6 EPR79258.1 - 0.17 11.3 1.1 0.23 10.9 0.7 1.3 1 1 0 1 1 1 0 WisP family C-Terminal Region Flu_NS2 PF00601.14 EPR79258.1 - 0.19 11.9 0.9 2.6 8.3 0.0 2.1 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) AAA PF00004.24 EPR79259.1 - 2.4e-43 147.4 0.3 6.1e-43 146.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPR79259.1 - 4.1e-07 29.7 0.2 3.4e-06 26.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPR79259.1 - 3.4e-06 27.0 0.6 2e-05 24.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPR79259.1 - 3e-05 23.1 0.0 7.6e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPR79259.1 - 0.00019 21.4 0.0 0.047 13.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPR79259.1 - 0.00028 21.0 2.1 0.074 13.1 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EPR79259.1 - 0.00046 20.0 0.1 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF1192 PF06698.6 EPR79259.1 - 0.0059 16.3 0.5 0.02 14.7 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1192) AAA_17 PF13207.1 EPR79259.1 - 0.0064 17.3 1.3 0.021 15.6 0.1 2.5 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPR79259.1 - 0.0081 15.3 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPR79259.1 - 0.013 14.8 0.5 1.1 8.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.1 EPR79259.1 - 0.015 14.8 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EPR79259.1 - 0.017 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EPR79259.1 - 0.018 15.3 0.1 0.11 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPR79259.1 - 0.022 14.4 0.1 0.05 13.3 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EPR79259.1 - 0.023 13.6 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EPR79259.1 - 0.025 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EPR79259.1 - 0.033 13.8 0.1 0.54 9.9 0.0 2.7 3 0 0 3 3 3 0 NTPase PhoH PF02562.11 EPR79259.1 - 0.035 13.3 0.1 0.09 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 EPR79259.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPR79259.1 - 0.064 12.7 0.1 1.7 8.0 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EPR79259.1 - 0.071 12.2 0.1 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 KaiC CENP-F_leu_zip PF10473.4 EPR79259.1 - 0.081 12.7 1.1 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_24 PF13479.1 EPR79259.1 - 0.093 12.2 1.0 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_M16 PF00675.15 EPR79260.1 - 1.7e-32 112.2 3.5 1.5e-23 83.2 0.1 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPR79260.1 - 0.00019 21.1 0.5 0.0015 18.2 0.1 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Kinesin PF00225.18 EPR79261.1 - 3.9e-85 285.5 6.6 3.9e-85 285.5 4.6 2.2 2 1 0 2 2 2 1 Kinesin motor domain WD40 PF00400.27 EPR79261.1 - 2.4e-06 27.1 9.9 0.47 10.4 0.0 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat T2SE PF00437.15 EPR79261.1 - 0.037 12.9 0.0 0.037 12.9 0.0 2.2 2 1 0 2 2 2 0 Type II/IV secretion system protein DUF2296 PF10058.4 EPR79263.1 - 1.4e-16 59.9 0.3 2.6e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) YebO PF13974.1 EPR79263.1 - 0.014 15.1 1.0 0.014 15.1 0.7 2.1 2 1 1 3 3 3 0 YebO-like protein DUF1510 PF07423.6 EPR79263.1 - 0.041 13.2 6.2 0.29 10.4 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) zf-LITAF-like PF10601.4 EPR79263.1 - 0.2 11.5 3.0 0.42 10.4 0.0 2.8 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain DUF3753 PF12575.3 EPR79263.1 - 0.37 10.6 10.9 1.4 8.7 1.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) MRP-L46 PF11788.3 EPR79263.1 - 2.2 8.9 5.9 1 10.0 2.2 1.8 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 ATP-synt_8 PF00895.15 EPR79263.1 - 2.7 8.2 5.5 9.1 6.5 0.3 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 DUF417 PF04224.7 EPR79264.1 - 0.37 10.1 4.0 0.14 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF417 DUF3367 PF11847.3 EPR79264.1 - 4.1 5.2 5.3 5.9 4.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Fork_head PF00250.13 EPR79265.1 - 2.7e-09 36.9 0.7 2.7e-09 36.9 0.5 2.0 2 0 0 2 2 2 1 Fork head domain Epsilon_antitox PF08998.6 EPR79265.1 - 0.019 14.9 2.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial epsilon antitoxin PAN_1 PF00024.21 EPR79266.1 - 0.075 12.7 1.3 12 5.7 0.2 2.4 2 0 0 2 2 2 0 PAN domain FH2 PF02181.18 EPR79268.1 - 4.8e-27 94.8 18.4 4.8e-27 94.8 12.7 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Baculo_LEF-11 PF06385.7 EPR79268.1 - 0.022 14.8 6.8 0.02 14.9 2.7 2.6 2 0 0 2 2 2 0 Baculovirus LEF-11 protein ASFV_J13L PF05568.6 EPR79268.1 - 0.17 11.4 0.2 0.3 10.6 0.2 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Fork_head PF00250.13 EPR79269.1 - 1.4e-31 108.3 1.1 1.4e-31 108.3 0.7 3.2 2 1 1 3 3 3 2 Fork head domain Ribosomal_S2 PF00318.15 EPR79270.1 - 2.9e-32 111.6 0.2 1.5e-16 60.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Mvb12 PF09452.5 EPR79271.1 - 0.17 12.1 0.9 0.53 10.4 0.3 2.0 2 1 0 2 2 2 0 ESCRT-I subunit Mvb12 Ribosomal_L10 PF00466.15 EPR79272.1 - 5.9e-18 64.6 3.1 9.8e-18 63.9 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 EMP24_GP25L PF01105.19 EPR79273.1 - 9.4e-13 48.2 4.6 1.1e-12 48.0 3.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DALR_2 PF09190.6 EPR79273.1 - 0.095 12.9 0.9 0.57 10.4 0.6 2.2 1 1 0 1 1 1 0 DALR domain DUF485 PF04341.7 EPR79273.1 - 4.2 7.1 5.9 0.23 11.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Gti1_Pac2 PF09729.4 EPR79274.1 - 2.6e-36 125.0 2.5 1.9e-32 112.4 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family PRANC PF09372.5 EPR79274.1 - 0.078 12.9 4.9 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 PRANC domain TFIIB PF00382.14 EPR79275.1 - 1.6e-33 114.3 3.6 7e-22 77.0 0.4 2.7 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EPR79275.1 - 4.9e-13 48.1 6.3 8.8e-13 47.3 4.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EPR79275.1 - 0.0073 16.2 0.0 0.79 9.6 0.0 2.2 1 1 1 2 2 2 2 Cyclin, C-terminal domain HARE-HTH PF05066.8 EPR79275.1 - 0.02 15.2 0.0 6.2 7.2 0.0 2.5 2 0 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain Evr1_Alr PF04777.8 EPR79276.1 - 1.5e-27 95.3 2.2 1.9e-27 94.9 1.5 1.2 1 0 0 1 1 1 1 Erv1 / Alr family zf-C2HC_2 PF13913.1 EPR79276.1 - 0.053 13.1 0.7 0.13 11.9 0.5 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Oxidored_q3 PF00499.15 EPR79276.1 - 0.17 11.6 3.4 0.2 11.4 2.3 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Sgf11 PF08209.6 EPR79276.1 - 0.34 10.2 0.2 0.34 10.2 0.1 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pox_E10 PF04805.7 EPR79276.1 - 0.53 9.8 7.5 0.39 10.2 0.1 2.5 2 1 0 2 2 2 0 E10-like protein conserved region zf-H2C2_2 PF13465.1 EPR79276.1 - 1.1 9.7 5.8 3.3 8.1 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_L19e PF01280.15 EPR79277.1 - 2.6e-47 160.2 8.6 3.3e-47 159.9 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e SHOCT PF09851.4 EPR79277.1 - 0.0012 18.2 0.2 0.0038 16.6 0.1 1.9 1 0 0 1 1 1 1 Short C-terminal domain Adenine_glyco PF03352.8 EPR79277.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyladenine glycosylase DUF3253 PF11625.3 EPR79277.1 - 0.043 13.6 0.4 0.25 11.2 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3253) DUF2205 PF10224.4 EPR79277.1 - 0.052 13.1 1.7 0.095 12.2 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DHQ_synthase PF01761.15 EPR79278.1 - 0.74 8.6 4.1 0.72 8.7 2.1 1.5 1 1 1 2 2 2 0 3-dehydroquinate synthase TRAUB PF08164.7 EPR79278.1 - 1.5 9.0 8.5 1 9.5 3.5 2.5 1 1 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Sugar_tr PF00083.19 EPR79279.1 - 1.2e-54 185.5 33.1 6.1e-36 123.9 9.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPR79279.1 - 1.6e-12 46.8 29.0 1.6e-12 46.8 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPR79279.1 - 5.6e-10 38.1 26.1 2.8e-08 32.6 7.6 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein LRR_6 PF13516.1 EPR79280.1 - 1.3e-11 43.3 22.3 0.0083 16.0 0.1 9.2 9 1 1 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 EPR79280.1 - 6.4e-08 32.0 17.4 0.0063 16.1 0.9 5.4 3 2 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79280.1 - 1.2e-07 30.7 9.0 0.55 10.4 0.0 7.4 7 2 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 EPR79280.1 - 0.0003 20.4 11.5 0.03 14.0 0.1 5.5 3 3 2 6 6 6 2 Leucine rich repeat LRR_7 PF13504.1 EPR79280.1 - 0.00037 20.2 6.4 1.9 9.0 0.0 6.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_2 PF07723.8 EPR79280.1 - 0.018 15.5 4.5 1 9.9 0.2 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat FTH PF01827.22 EPR79280.1 - 0.21 11.1 8.4 0.37 10.3 0.4 3.3 3 0 0 3 3 3 0 FTH domain zf-H2C2_2 PF13465.1 EPR79281.1 - 2.2e-09 37.1 6.1 2.5e-06 27.5 1.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPR79281.1 - 2.1e-08 33.8 9.1 0.00065 19.8 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPR79281.1 - 3.7e-05 23.8 13.3 0.021 15.1 2.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPR79281.1 - 0.0076 16.1 4.1 0.029 14.2 1.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EPR79281.1 - 0.032 14.4 0.9 0.032 14.4 0.7 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EPR79281.1 - 0.97 9.8 6.3 0.42 11.0 1.7 2.2 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EPR79281.1 - 1 9.5 5.9 0.87 9.8 2.6 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DDE_3 PF13358.1 EPR79282.1 - 2.3e-09 37.1 0.1 4.9e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease G3P_antiterm PF04309.7 EPR79282.1 - 0.055 12.5 0.6 0.18 10.8 0.1 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Nop10p PF04135.7 EPR79284.1 - 2.9e-13 49.3 1.1 1.1e-12 47.4 0.7 1.7 1 1 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Aegerolysin PF06355.8 EPR79284.1 - 0.047 13.5 0.2 0.05 13.4 0.1 1.1 1 0 0 1 1 1 0 Aegerolysin Bromodomain PF00439.20 EPR79285.1 - 5.8e-10 38.9 0.8 9.2e-10 38.3 0.6 1.4 1 1 0 1 1 1 1 Bromodomain ATP-synt_D PF01813.12 EPR79286.1 - 1.5e-48 164.9 1.8 1.7e-48 164.7 1.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D DUF2458 PF10454.4 EPR79286.1 - 0.0069 16.2 0.7 0.13 12.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) MSP1b PF03429.8 EPR79286.1 - 0.037 11.9 0.0 0.047 11.5 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B SCA7 PF08313.7 EPR79287.1 - 1.1e-07 31.3 2.7 1.9e-07 30.5 1.9 1.4 1 0 0 1 1 1 1 SCA7, zinc-binding domain Fiji_64_capsid PF05880.6 EPR79287.1 - 0.0032 15.9 2.1 0.0037 15.6 1.5 1.0 1 0 0 1 1 1 1 Fijivirus 64 kDa capsid protein DUF382 PF04037.8 EPR79289.1 - 7.9e-19 67.7 2.8 7.9e-19 67.7 1.9 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 EPR79289.1 - 3.2e-07 29.6 0.1 7.4e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 PSP SnAC PF14619.1 EPR79289.1 - 0.03 14.4 0.7 0.03 14.4 0.5 3.0 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex RNA_pol_Rpb1_5 PF04998.12 EPR79289.1 - 0.65 9.1 4.1 1 8.5 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3492 PF11997.3 EPR79289.1 - 1.1 8.7 4.7 0.41 10.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Arf PF00025.16 EPR79290.1 - 5e-47 159.3 0.0 5.9e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPR79290.1 - 3.6e-12 45.9 0.1 4.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPR79290.1 - 6.3e-10 38.2 0.2 3.4e-07 29.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPR79290.1 - 3.5e-09 36.1 0.0 4.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPR79290.1 - 6.7e-06 26.5 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPR79290.1 - 9.2e-05 22.3 0.1 0.00019 21.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPR79290.1 - 0.00093 18.4 0.0 0.0012 18.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPR79290.1 - 0.06 12.7 0.3 0.35 10.2 0.2 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.10 EPR79290.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NTPase DDT PF02791.12 EPR79291.1 - 0.00045 19.9 0.5 0.00091 18.9 0.4 1.5 1 0 0 1 1 1 1 DDT domain AOX PF01786.12 EPR79292.1 - 4.6e-71 238.4 0.1 5.9e-71 238.1 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Met_10 PF02475.11 EPR79295.1 - 9.4e-47 159.1 3.4 1.3e-46 158.7 2.4 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EPR79295.1 - 8.7e-08 31.7 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EPR79295.1 - 6.8e-07 28.6 0.4 1.3e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EPR79295.1 - 4.1e-06 26.4 1.1 5.6e-06 26.0 0.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR79295.1 - 5.8e-06 26.8 0.0 9.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 EPR79295.1 - 1.9e-05 23.7 2.1 7.1e-05 21.9 0.1 2.1 1 1 1 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EPR79295.1 - 0.00015 21.7 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EPR79295.1 - 0.0008 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.5 EPR79295.1 - 0.0023 17.5 0.2 0.0023 17.5 0.1 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.4 EPR79295.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EPR79295.1 - 0.0062 15.7 0.2 0.013 14.6 0.1 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 EPR79295.1 - 0.049 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EPR79295.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RhoGAP PF00620.22 EPR79296.1 - 2.6e-17 62.8 0.2 8.5e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain His_Phos_2 PF00328.17 EPR79297.1 - 7e-22 78.2 0.0 1.9e-11 43.8 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) VWC PF00093.13 EPR79297.1 - 0.034 14.2 6.1 0.24 11.5 0.8 2.6 2 0 0 2 2 2 0 von Willebrand factor type C domain SPRY PF00622.23 EPR79299.1 - 1.7e-10 41.0 6.2 5.6e-08 32.9 4.3 2.3 1 1 0 1 1 1 1 SPRY domain Ribosomal_60s PF00428.14 EPR79300.1 - 6.7e-12 45.6 5.2 7.6e-12 45.4 3.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein HrcA_DNA-bdg PF03444.10 EPR79300.1 - 0.11 11.9 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF3332 PF11810.3 EPR79300.1 - 0.2 11.2 1.0 0.24 11.0 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Cyclin PF08613.6 EPR79301.1 - 1.2e-08 35.4 1.7 5.9e-08 33.2 0.2 2.1 2 0 0 2 2 2 1 Cyclin Spo0A_C PF08769.6 EPR79301.1 - 0.1 12.4 1.3 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal DUF1430 PF07242.6 EPR79301.1 - 0.48 10.5 5.8 1.3 9.0 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1430) DEAD PF00270.24 EPR79303.1 - 2.3e-28 98.7 0.2 8e-28 97.0 0.2 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.11 EPR79303.1 - 1.4e-21 77.0 6.0 1.4e-21 77.0 4.2 2.0 2 0 0 2 2 2 1 Sec63 Brl domain Helicase_C PF00271.26 EPR79303.1 - 6.2e-08 32.3 0.0 1.8e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EPR79303.1 - 0.001 18.0 0.0 0.0042 16.0 0.0 2.1 1 0 0 1 1 1 1 Type II/IV secretion system protein CobA_CobO_BtuR PF02572.10 EPR79303.1 - 0.0013 18.3 0.2 0.009 15.6 0.0 2.2 2 0 0 2 2 2 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_19 PF13245.1 EPR79303.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Cation_efflux PF01545.16 EPR79304.1 - 7e-55 186.1 18.5 8e-55 185.9 12.8 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4149 PF13664.1 EPR79304.1 - 2.4 8.2 6.5 0.42 10.6 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Proteasome PF00227.21 EPR79305.1 - 8.1e-48 162.2 2.4 1e-47 161.8 1.6 1.1 1 0 0 1 1 1 1 Proteasome subunit PSS PF03034.10 EPR79306.1 - 7.8e-61 205.9 15.8 7.8e-61 205.9 10.9 2.0 2 1 0 2 2 2 1 Phosphatidyl serine synthase Sulfate_transp PF00916.15 EPR79306.1 - 0.026 13.5 0.2 0.026 13.5 0.2 2.2 2 1 1 3 3 3 0 Sulfate transporter family DUF443 PF04276.7 EPR79307.1 - 0.1 12.0 1.0 0.29 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF443) FAM163 PF15069.1 EPR79307.1 - 1.7 9.2 5.7 1.6 9.2 0.3 2.6 2 0 0 2 2 2 0 FAM163 family DUF106 PF01956.11 EPR79307.1 - 2.6 7.5 5.7 39 3.7 3.1 2.5 2 0 0 2 2 2 0 Integral membrane protein DUF106 Ctr PF04145.10 EPR79308.1 - 0.00023 21.2 4.8 0.00023 21.2 3.3 1.6 1 1 1 2 2 2 1 Ctr copper transporter family MreD PF04093.7 EPR79308.1 - 0.031 14.1 4.6 0.039 13.8 3.2 1.1 1 0 0 1 1 1 0 rod shape-determining protein MreD GpcrRhopsn4 PF10192.4 EPR79308.1 - 0.064 12.4 9.5 0.051 12.7 5.7 1.5 1 1 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Selenoprotein_S PF06936.6 EPR79308.1 - 0.13 11.7 0.2 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF2614 PF11023.3 EPR79308.1 - 0.18 11.6 3.8 0.21 11.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Pkinase PF00069.20 EPR79309.1 - 4.2e-47 160.4 0.0 5.1e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79309.1 - 2.3e-28 99.0 0.0 2.9e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79309.1 - 1e-08 34.4 0.0 2.9e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPR79309.1 - 6.3e-07 29.3 0.0 4.9e-05 23.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPR79309.1 - 1.9e-05 24.0 1.0 0.00015 21.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EPR79309.1 - 0.00074 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EPR79309.1 - 0.0094 15.5 2.1 0.03 13.8 1.4 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase WaaY PF06176.6 EPR79309.1 - 0.042 13.0 2.7 0.081 12.1 1.9 1.4 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) 2OG-FeII_Oxy_3 PF13640.1 EPR79311.1 - 1.8e-06 28.3 3.0 0.03 14.8 0.2 2.8 2 1 1 3 3 3 2 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.13 EPR79313.1 - 3e-34 118.2 51.0 5.9e-34 117.2 35.3 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EPR79313.1 - 0.0014 17.2 58.4 0.0065 15.0 40.5 1.9 1 1 0 1 1 1 1 Amino acid permease Ferric_reduct PF01794.14 EPR79313.1 - 3.8 7.6 13.9 2.7 8.1 6.4 2.6 2 1 0 2 2 2 0 Ferric reductase like transmembrane component RNA_pol_Rpb1_6 PF04992.9 EPR79314.1 - 0.035 13.8 0.2 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Hema_HEFG PF02710.9 EPR79314.1 - 0.098 12.9 0.1 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein DS PF01916.12 EPR79314.1 - 0.16 11.0 0.5 0.16 11.0 0.3 1.0 1 0 0 1 1 1 0 Deoxyhypusine synthase ABC_tran PF00005.22 EPR79317.1 - 1.1e-31 109.9 0.4 2.7e-31 108.6 0.1 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EPR79317.1 - 3.6e-17 62.6 16.7 5.1e-17 62.1 11.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EPR79317.1 - 1.9e-07 31.3 9.5 1.9e-07 31.3 6.6 3.5 1 1 1 3 3 3 1 AAA domain SMC_N PF02463.14 EPR79317.1 - 7.1e-06 25.4 5.1 0.0017 17.6 3.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EPR79317.1 - 9e-05 21.2 0.1 0.011 14.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class PG_binding_2 PF08823.6 EPR79317.1 - 0.00066 19.7 0.0 0.57 10.3 0.0 2.6 2 0 0 2 2 2 1 Putative peptidoglycan binding domain DUF258 PF03193.11 EPR79317.1 - 0.00068 18.8 0.0 0.0016 17.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 EPR79317.1 - 0.0012 17.8 0.0 0.0032 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Miro PF08477.8 EPR79317.1 - 0.0026 18.2 0.2 0.0082 16.6 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EPR79317.1 - 0.0035 17.4 0.1 0.0098 16.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR79317.1 - 0.007 17.1 0.7 0.021 15.6 0.5 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EPR79317.1 - 0.015 15.0 0.4 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EPR79317.1 - 0.018 15.1 0.1 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EPR79317.1 - 0.02 14.7 0.3 0.02 14.7 0.2 2.9 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.1 EPR79317.1 - 0.022 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPR79317.1 - 0.047 12.7 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 EPR79317.1 - 0.048 13.6 0.0 0.096 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EPR79317.1 - 0.05 13.9 12.8 0.028 14.7 5.5 2.2 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EPR79317.1 - 0.052 12.8 0.3 5.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 EPR79317.1 - 0.052 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EPR79317.1 - 0.065 12.9 0.2 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EPR79317.1 - 0.11 12.4 0.3 1.5 8.7 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EPR79317.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EPR79317.1 - 0.15 12.0 3.2 0.71 9.8 2.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPR79317.1 - 0.19 11.1 0.0 0.64 9.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EPR79317.1 - 1.2 8.8 4.5 2.7 7.7 0.2 2.7 3 0 0 3 3 3 0 Dynamin family Spindle_Spc25 PF08234.7 EPR79318.1 - 0.0005 20.0 0.5 0.0019 18.1 0.1 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DivIC PF04977.10 EPR79318.1 - 0.02 14.3 5.9 0.02 14.3 4.1 3.8 1 1 2 3 3 3 0 Septum formation initiator APG6 PF04111.7 EPR79318.1 - 0.1 11.6 24.5 0.17 10.9 17.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EPR79318.1 - 0.21 10.5 22.8 0.39 9.6 15.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mem_trans PF03547.13 EPR79318.1 - 0.31 9.2 2.3 0.39 8.9 1.6 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4407 PF14362.1 EPR79318.1 - 0.7 8.7 6.7 1.1 8.1 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 EPR79318.1 - 0.74 9.6 28.1 1.4 8.7 19.5 1.5 1 0 0 1 1 1 0 Tropomyosin like DUF3810 PF12725.2 EPR79318.1 - 1.7 7.5 11.9 0.97 8.2 6.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF2009 PF09418.5 EPR79318.1 - 1.8 7.2 13.4 2.7 6.6 8.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) TMF_TATA_bd PF12325.3 EPR79318.1 - 2.1 8.1 23.2 3.8 7.2 14.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.6 EPR79318.1 - 3.8 7.4 10.1 4.6 7.1 2.3 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.1 EPR79318.1 - 6.6 6.9 17.3 3.4 7.8 1.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) GATA PF00320.22 EPR79319.1 - 1.7e-07 30.4 5.9 1.7e-07 30.4 4.1 2.1 2 0 0 2 2 2 1 GATA zinc finger DUF2318 PF10080.4 EPR79319.1 - 0.054 13.2 1.8 0.071 12.8 0.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) LIM PF00412.17 EPR79319.1 - 2.3 8.3 9.3 0.12 12.4 0.6 2.8 3 0 0 3 3 3 0 LIM domain PHD PF00628.24 EPR79319.1 - 4.4 7.0 8.6 11 5.8 0.1 3.2 3 0 0 3 3 3 0 PHD-finger RasGAP_C PF03836.10 EPR79320.1 - 8.9e-22 77.3 9.8 8.9e-22 77.3 6.8 4.4 5 0 0 5 5 5 1 RasGAP C-terminus CH PF00307.26 EPR79320.1 - 3.5e-10 39.8 2.2 8.1e-10 38.7 0.0 2.7 3 0 0 3 3 3 1 Calponin homology (CH) domain tRNA-synt_2b PF00587.20 EPR79321.1 - 1.6e-51 174.3 4.0 4.6e-51 172.8 2.1 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPR79321.1 - 2.6e-15 56.1 0.2 1.2e-14 54.0 0.2 2.2 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EPR79321.1 - 0.035 13.2 0.1 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DNA_pol_B PF00136.16 EPR79322.1 - 1.8e-133 445.7 6.8 2.6e-133 445.2 4.7 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPR79322.1 - 3.3e-56 190.5 13.6 3.3e-56 190.5 9.4 2.4 2 1 1 3 3 3 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPR79322.1 - 6.2e-16 58.1 11.7 1.5e-15 56.9 8.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EPR79322.1 - 0.00075 19.3 0.0 0.0032 17.2 0.0 2.2 1 1 0 1 1 1 1 RNase_H superfamily Cul7 PF11515.3 EPR79322.1 - 0.021 14.7 0.4 0.092 12.6 0.4 1.9 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 PerB PF06590.6 EPR79323.1 - 0.058 13.7 0.8 0.1 12.9 0.5 1.5 1 0 0 1 1 1 0 PerB protein DUF3557 PF12078.3 EPR79323.1 - 0.06 13.0 1.5 0.24 11.0 1.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3557) DRIM PF07539.7 EPR79323.1 - 0.14 11.6 2.8 0.14 11.5 1.3 1.5 1 1 1 2 2 2 0 Down-regulated in metastasis mRNA_cap_enzyme PF01331.14 EPR79324.1 - 6.5e-25 87.9 3.5 1.4e-24 86.8 2.4 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EPR79324.1 - 1.5e-10 41.3 7.5 7e-10 39.1 5.2 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EPR79324.1 - 1.2e-05 24.7 3.0 0.00021 20.7 0.1 2.6 2 1 1 3 3 3 2 ATP dependent DNA ligase domain DUF2024 PF09630.5 EPR79324.1 - 0.066 12.9 0.8 0.32 10.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) LRR_8 PF13855.1 EPR79325.1 - 5.6e-16 58.0 25.2 5.4e-07 29.2 2.1 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EPR79325.1 - 7.2e-16 57.4 27.2 8.7e-08 31.6 3.3 4.0 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79325.1 - 1.4e-07 30.5 19.7 0.61 10.3 0.0 7.0 6 1 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR79325.1 - 5.4e-06 25.7 11.4 1.8 9.1 0.0 6.1 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EPR79325.1 - 1.1 9.4 8.6 39 4.7 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeat zf-DHHC PF01529.15 EPR79326.1 - 2e-26 92.4 11.2 2e-26 92.4 7.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Elf1 PF05129.8 EPR79327.1 - 1.4e-19 69.5 8.6 1.7e-19 69.3 5.9 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like C1_4 PF07975.7 EPR79327.1 - 0.017 15.0 6.4 0.017 15.0 4.4 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain Lar_restr_allev PF14354.1 EPR79327.1 - 0.21 11.9 2.3 0.25 11.6 1.6 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar DRP PF06044.7 EPR79327.1 - 0.32 9.9 3.9 0.36 9.7 2.7 1.1 1 0 0 1 1 1 0 Dam-replacing family DUF2387 PF09526.5 EPR79327.1 - 1.1 9.2 5.7 1.4 8.8 3.9 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-CHY PF05495.7 EPR79327.1 - 1.2 9.3 9.7 1.7 8.8 6.7 1.4 1 1 0 1 1 1 0 CHY zinc finger Cytochrome_C7 PF14522.1 EPR79327.1 - 1.2 8.8 6.9 1.2 8.8 4.1 1.4 1 1 0 1 1 1 0 Cytochrome c7 zf-TFIIB PF13453.1 EPR79327.1 - 2.1 7.6 6.3 3.3 6.9 2.8 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_Tnp_IS1595 PF12760.2 EPR79327.1 - 6.9 6.5 8.3 16 5.3 5.7 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain S_layer_N PF05123.7 EPR79328.1 - 0.39 10.2 3.5 5.5 6.5 0.3 2.1 1 1 1 2 2 2 0 S-layer like family, N-terminal region DNA_pol3_delta2 PF13177.1 EPR79329.1 - 4.4e-16 58.9 0.2 2.2e-13 50.1 0.1 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPR79329.1 - 1.1e-15 57.9 0.1 2.3e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EPR79329.1 - 1.2e-11 44.3 0.2 4.7e-11 42.5 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EPR79329.1 - 3.3e-08 33.7 0.2 0.0017 18.5 0.0 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EPR79329.1 - 1.1e-07 31.1 0.1 8.1e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 EPR79329.1 - 6.6e-07 28.9 2.4 6.6e-07 28.9 1.6 1.9 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EPR79329.1 - 7.6e-07 29.0 0.2 2.4e-06 27.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EPR79329.1 - 8.4e-06 24.7 2.1 0.0052 15.5 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EPR79329.1 - 1.3e-05 25.9 0.0 2.7e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR79329.1 - 1.3e-05 25.4 1.4 3.8e-05 23.9 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EPR79329.1 - 0.00013 22.0 0.0 0.00041 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EPR79329.1 - 0.00014 21.4 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EPR79329.1 - 0.0003 20.5 0.2 0.0011 18.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPR79329.1 - 0.00031 19.9 0.0 0.0013 17.9 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EPR79329.1 - 0.0005 19.3 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 TIP49 PF06068.8 EPR79329.1 - 0.00054 18.7 1.7 0.0089 14.7 1.2 2.1 1 1 0 1 1 1 1 TIP49 C-terminus AAA_3 PF07726.6 EPR79329.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPR79329.1 - 0.00059 19.3 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EPR79329.1 - 0.0013 18.4 3.5 0.15 11.7 0.2 2.5 1 1 1 2 2 2 2 NTPase PhoH PF02562.11 EPR79329.1 - 0.0023 17.1 0.2 1.2 8.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.17 EPR79329.1 - 0.0025 17.9 0.5 0.019 15.0 0.1 2.5 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 EPR79329.1 - 0.003 17.1 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EPR79329.1 - 0.0031 17.5 0.0 0.0073 16.3 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 EPR79329.1 - 0.0033 17.4 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPR79329.1 - 0.0041 16.6 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EPR79329.1 - 0.0044 16.4 0.5 0.049 13.0 0.3 2.4 1 1 0 1 1 1 1 AAA-like domain DEAD PF00270.24 EPR79329.1 - 0.0051 16.3 0.9 0.52 9.7 0.0 2.7 1 1 2 3 3 3 1 DEAD/DEAH box helicase AAA_33 PF13671.1 EPR79329.1 - 0.0071 16.2 0.1 0.019 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_gamma3 PF12169.3 EPR79329.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III T2SE PF00437.15 EPR79329.1 - 0.011 14.6 0.1 0.025 13.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EPR79329.1 - 0.013 15.8 0.6 0.048 13.9 0.4 2.1 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EPR79329.1 - 0.013 15.1 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_11 PF13086.1 EPR79329.1 - 0.014 15.0 0.9 0.094 12.2 0.5 2.4 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EPR79329.1 - 0.03 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 EPR79329.1 - 0.035 13.6 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPR79329.1 - 0.043 13.3 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 EPR79329.1 - 0.048 13.4 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit DUF815 PF05673.8 EPR79329.1 - 0.077 11.9 0.2 1.1 8.1 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF815) PPR_2 PF13041.1 EPR79329.1 - 0.077 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 1 0 PPR repeat family PPR PF01535.15 EPR79329.1 - 0.077 13.0 1.1 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 PPR repeat Zeta_toxin PF06414.7 EPR79329.1 - 0.084 11.9 0.0 2.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Zeta toxin PPR_1 PF12854.2 EPR79329.1 - 0.088 12.3 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 PPR repeat AAA_25 PF13481.1 EPR79329.1 - 0.16 11.3 0.2 0.42 9.9 0.1 1.7 1 1 1 2 2 2 0 AAA domain HrcA_DNA-bdg PF03444.10 EPR79329.1 - 0.47 9.9 2.5 0.89 9.0 0.4 2.4 3 0 0 3 3 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding zf-Nse PF11789.3 EPR79330.1 - 3.4e-13 48.8 0.9 6e-13 48.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPR79330.1 - 7.9e-06 25.4 1.9 8.7e-06 25.3 0.3 1.8 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 EPR79330.1 - 9.2e-06 25.5 0.4 2.3e-05 24.2 0.0 1.8 3 0 0 3 3 3 1 U-box domain zf-RING_2 PF13639.1 EPR79330.1 - 0.00013 21.7 0.2 0.00021 21.0 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPR79330.1 - 0.00025 20.9 0.3 0.00056 19.8 0.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPR79330.1 - 0.0032 17.5 0.2 0.0069 16.4 0.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPR79330.1 - 0.0034 17.0 0.3 0.0048 16.5 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EPR79330.1 - 0.0052 16.0 5.3 0.01 15.0 0.3 2.1 1 1 1 2 2 2 2 Rtf2 RING-finger zf-C3HC4 PF00097.20 EPR79330.1 - 0.006 16.2 0.3 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR79330.1 - 0.018 14.7 0.3 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2570 PF10828.3 EPR79330.1 - 0.047 13.2 4.2 0.082 12.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Tex_N PF09371.5 EPR79330.1 - 0.05 12.9 3.0 0.078 12.2 2.1 1.3 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF4038 PF13204.1 EPR79330.1 - 0.072 12.4 0.2 0.091 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) zf-MIZ PF02891.15 EPR79330.1 - 0.15 11.6 0.6 0.32 10.5 0.4 1.5 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger MOZ_SAS PF01853.13 EPR79331.1 - 2.8e-56 189.7 4.4 4.9e-56 188.9 3.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family C1_1 PF00130.17 EPR79331.1 - 0.00092 18.8 32.5 0.099 12.3 6.7 3.4 2 1 1 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_7 PF13508.1 EPR79331.1 - 0.0063 16.6 0.0 0.023 14.8 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PHD PF00628.24 EPR79331.1 - 0.015 14.9 8.6 0.015 14.9 6.0 3.6 2 1 1 3 3 3 0 PHD-finger DUF2582 PF10771.4 EPR79331.1 - 0.019 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) Acetyltransf_10 PF13673.1 EPR79331.1 - 0.023 14.8 0.0 0.066 13.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Prok-RING_1 PF14446.1 EPR79331.1 - 0.23 11.2 29.8 0.052 13.2 8.7 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Aa_trans PF01490.13 EPR79332.1 - 4.9e-53 180.0 41.6 6e-53 179.8 28.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPR79332.1 - 8.4e-07 28.1 23.3 1.5e-05 24.0 12.7 2.2 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family AAA_22 PF13401.1 EPR79334.1 - 9.5e-06 25.7 2.1 0.024 14.7 0.1 2.7 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.1 EPR79334.1 - 0.00018 21.1 3.9 0.00025 20.6 2.7 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EPR79334.1 - 0.00025 21.2 6.0 0.0013 18.9 0.8 3.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPR79334.1 - 0.00059 19.4 0.0 0.013 15.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPR79334.1 - 0.0048 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 EPR79334.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPR79334.1 - 0.0097 15.9 0.0 0.022 14.7 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EPR79334.1 - 0.016 14.1 0.2 0.036 12.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EPR79334.1 - 0.018 13.8 2.2 0.07 11.9 1.5 2.3 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EPR79334.1 - 0.032 14.1 0.1 0.056 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EPR79334.1 - 0.042 13.0 0.5 0.1 11.7 0.3 1.9 1 1 1 2 2 2 0 PhoH-like protein DEAD PF00270.24 EPR79334.1 - 0.05 13.0 1.7 0.12 11.8 0.3 2.2 2 1 0 2 2 2 0 DEAD/DEAH box helicase KaiC PF06745.8 EPR79334.1 - 0.051 12.6 9.5 0.2 10.7 0.1 3.2 1 1 2 3 3 3 0 KaiC AAA_17 PF13207.1 EPR79334.1 - 0.051 14.3 2.0 0.21 12.4 1.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPR79334.1 - 0.13 12.5 12.8 0.15 12.3 0.4 2.3 1 1 0 2 2 2 0 AAA domain LRR_4 PF12799.2 EPR79335.1 - 3.4e-40 135.0 159.4 1.1e-05 24.9 1.6 20.7 13 7 10 23 23 23 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79335.1 - 8.6e-22 76.6 128.6 2.1e-06 27.3 2.3 17.5 14 6 3 17 17 17 11 Leucine rich repeat LRR_1 PF00560.28 EPR79335.1 - 2.3e-08 32.9 99.0 0.26 11.4 0.1 24.5 20 4 5 25 25 25 6 Leucine Rich Repeat FNIP PF05725.7 EPR79335.1 - 7.6 6.5 81.7 0.56 10.2 2.4 15.0 12 2 3 15 15 15 0 FNIP Repeat La PF05383.12 EPR79337.1 - 2.4e-15 56.0 1.3 5.1e-15 55.0 0.1 2.2 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 EPR79337.1 - 1.2e-06 28.3 0.2 6.5e-05 22.8 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Erv26 PF04148.8 EPR79338.1 - 1.2e-23 83.5 24.3 9.7e-23 80.6 16.8 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1129 PF06570.6 EPR79338.1 - 2.7 7.2 12.5 0.72 9.1 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) ADK PF00406.17 EPR79340.1 - 3.5e-42 143.8 0.1 4.3e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EPR79340.1 - 1.1e-08 35.4 1.5 2e-08 34.5 1.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR79340.1 - 6e-06 27.0 1.9 9.3e-06 26.4 1.3 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPR79340.1 - 1.5e-05 24.4 1.9 0.0018 17.6 0.1 2.2 1 1 1 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EPR79340.1 - 3.9e-05 23.5 0.0 8.1e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPR79340.1 - 0.0028 17.6 0.0 0.0073 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPR79340.1 - 0.0069 15.5 0.1 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA PF00004.24 EPR79340.1 - 0.0085 16.2 1.2 0.038 14.1 0.8 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EPR79340.1 - 0.038 13.8 0.3 0.86 9.4 0.2 2.2 1 1 0 1 1 1 0 Shikimate kinase Cytidylate_kin2 PF13189.1 EPR79340.1 - 0.038 13.8 1.3 0.41 10.5 0.9 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family Csm1 PF12539.3 EPR79341.1 - 0.0069 16.8 0.2 0.23 11.9 0.2 2.5 1 1 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Filamin PF00630.14 EPR79341.1 - 0.12 12.9 2.5 0.21 12.1 1.7 1.4 1 1 0 1 1 1 0 Filamin/ABP280 repeat Pox_Ag35 PF03286.9 EPR79341.1 - 0.22 11.0 9.3 0.3 10.5 6.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hom_end_hint PF05203.11 EPR79341.1 - 5 6.8 7.2 8.4 6.0 5.0 1.3 1 1 0 1 1 1 0 Hom_end-associated Hint Pkinase PF00069.20 EPR79342.1 - 1.6e-40 138.9 1.0 2.2e-40 138.4 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79342.1 - 1.3e-20 73.5 0.2 1.8e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79342.1 - 6.1e-06 25.4 0.0 9.5e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPR79342.1 - 0.00096 18.2 0.1 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR79342.1 - 0.0019 17.9 0.1 0.003 17.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Latexin PF06907.7 EPR79342.1 - 0.054 12.6 0.1 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Latexin WD40 PF00400.27 EPR79343.1 - 0.00028 20.6 0.0 0.017 14.9 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat AAA_21 PF13304.1 EPR79344.1 - 0.69 9.8 18.2 0.85 9.5 12.6 1.0 1 0 0 1 1 1 0 AAA domain Peptidase_C6 PF00851.13 EPR79345.1 - 0.0024 16.5 1.6 0.0029 16.3 1.1 1.1 1 0 0 1 1 1 1 Helper component proteinase Cytochrom_B562 PF07361.6 EPR79345.1 - 0.011 16.1 3.4 0.012 16.0 0.3 2.1 1 1 1 2 2 2 0 Cytochrome b562 LEDGF PF11467.3 EPR79345.1 - 0.02 14.5 1.4 0.046 13.4 0.0 2.0 1 1 1 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) ELFV_dehydrog PF00208.16 EPR79345.1 - 0.12 11.9 1.3 0.17 11.4 0.9 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ATP-synt_B PF00430.13 EPR79345.1 - 0.2 11.4 3.7 0.3 10.8 2.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MSA-2c PF12238.3 EPR79345.1 - 0.29 10.7 6.5 0.49 10.0 4.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c RPW8 PF05659.6 EPR79345.1 - 0.82 9.1 5.9 1.4 8.4 4.1 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 GIDA_assoc_3 PF13932.1 EPR79345.1 - 8.1 6.5 6.7 1.9 8.5 2.2 1.8 2 0 0 2 2 2 0 GidA associated domain 3 EMG1 PF03587.9 EPR79346.1 - 7.2e-48 162.5 1.0 8.7e-48 162.2 0.7 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF3892 PF13031.1 EPR79346.1 - 0.093 13.1 0.1 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) Fork_head PF00250.13 EPR79347.1 - 1.5e-27 95.4 1.1 2.9e-27 94.5 0.8 1.4 1 0 0 1 1 1 1 Fork head domain MTS PF05175.9 EPR79348.1 - 7.8e-14 51.3 0.1 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPR79348.1 - 1e-11 44.8 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPR79348.1 - 2.6e-08 33.6 0.3 3.4e-08 33.2 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR79348.1 - 4.2e-07 30.5 0.0 5.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPR79348.1 - 4.8e-07 29.1 0.0 8.7e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EPR79348.1 - 5.3e-07 29.1 0.0 6.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EPR79348.1 - 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPR79348.1 - 2.6e-05 24.5 0.0 5.2e-05 23.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.13 EPR79348.1 - 0.0003 20.4 0.0 0.00056 19.5 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EPR79348.1 - 0.00058 19.0 0.2 0.0013 17.8 0.1 1.6 1 1 0 1 1 1 1 N-6 DNA Methylase RrnaAD PF00398.15 EPR79348.1 - 0.00077 18.5 0.0 0.0011 18.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EPR79348.1 - 0.0055 16.4 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPR79348.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EPR79348.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.4 EPR79348.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.7 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.7 EPR79348.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EPR79348.1 - 0.051 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cadherin PF00028.12 EPR79348.1 - 0.073 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Cadherin domain Scm3 PF10384.4 EPR79350.1 - 0.017 14.6 0.7 0.048 13.1 0.5 1.8 1 0 0 1 1 1 0 Centromere protein Scm3 DOR PF14839.1 EPR79350.1 - 0.77 9.4 8.6 1 9.0 6.0 1.1 1 0 0 1 1 1 0 DOR family CDP-OH_P_transf PF01066.16 EPR79351.1 - 1.8e-11 44.2 9.5 3.1e-11 43.4 6.6 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CDP-OH_P_transf PF01066.16 EPR79352.1 - 1.5e-13 50.8 7.2 4.5e-13 49.3 5.0 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase YmgB PF10798.3 EPR79352.1 - 0.15 11.8 0.5 0.44 10.3 0.4 1.7 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR Rad51 PF08423.6 EPR79355.1 - 2.2e-118 393.8 0.1 2.7e-118 393.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPR79355.1 - 2.6e-13 49.7 0.0 4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EPR79355.1 - 1.1e-10 41.1 0.1 2.1e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EPR79355.1 - 1.6e-09 37.2 0.6 1.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 EPR79355.1 - 4.3e-05 23.6 0.0 0.00016 21.7 0.0 2.0 1 1 1 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 EPR79355.1 - 0.053 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 PAXNEB protein Homeobox PF00046.24 EPR79356.1 - 5.3e-18 64.3 2.6 8.5e-18 63.7 1.8 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPR79356.1 - 0.0068 16.0 0.1 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Homeobox KN domain DUF658 PF04936.7 EPR79356.1 - 0.026 14.3 0.1 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) DUF4476 PF14771.1 EPR79356.1 - 0.071 13.1 0.7 1 9.4 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4476) TBPIP PF07106.8 EPR79357.1 - 2.1e-15 56.6 22.2 2.1e-15 56.6 15.4 2.0 1 1 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TFIIA_gamma_N PF02268.11 EPR79357.1 - 0.073 12.6 0.3 1.1 8.9 0.0 2.7 2 1 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Tweety PF04906.8 EPR79357.1 - 0.18 10.1 4.2 0.14 10.5 1.7 1.6 1 1 0 1 1 1 0 Tweety GvpL_GvpF PF06386.6 EPR79357.1 - 2.5 7.6 15.0 0.053 13.0 5.6 1.8 2 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF AAA_13 PF13166.1 EPR79357.1 - 8.2 4.7 41.5 0.0066 14.9 16.8 2.0 1 1 1 2 2 2 0 AAA domain HTH_3 PF01381.17 EPR79358.1 - 1.3e-05 24.9 0.1 2.1e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EPR79358.1 - 0.00049 20.1 0.4 0.00066 19.6 0.3 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain MSC PF09402.5 EPR79358.1 - 0.06 12.0 0.1 0.065 11.9 0.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF4362 PF14275.1 EPR79359.1 - 0.019 15.0 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) ubiquitin PF00240.18 EPR79360.1 - 1.5e-11 43.4 0.7 2.6e-11 42.7 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EPR79360.1 - 0.00019 21.5 0.1 0.00023 21.2 0.1 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EPR79360.1 - 0.0002 20.9 1.5 0.00033 20.2 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EPR79360.1 - 0.00068 19.5 0.6 0.00092 19.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPR79360.1 - 0.018 15.2 0.2 0.05 13.8 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain DUF3169 PF11368.3 EPR79360.1 - 0.028 13.6 1.0 0.038 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF3837 PF12939.2 EPR79360.1 - 0.082 12.9 0.7 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) UBA PF00627.26 EPR79361.1 - 1.1e-05 25.0 0.0 1.1e-05 25.0 0.0 2.2 3 1 0 3 3 3 1 UBA/TS-N domain Pex19 PF04614.7 EPR79361.1 - 0.0038 16.8 1.1 0.0057 16.3 0.7 1.2 1 0 0 1 1 1 1 Pex19 protein family MCC-bdg_PDZ PF10506.4 EPR79361.1 - 0.17 11.7 0.4 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3366 PF11846.3 EPR79363.1 - 0.13 12.1 0.2 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) DUF3139 PF11337.3 EPR79363.1 - 0.19 12.0 0.9 1.1 9.6 0.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4014 PF13198.1 EPR79363.1 - 1.2 9.6 7.1 1.9 8.9 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) zf-GRF PF06839.7 EPR79364.1 - 1.7e-13 50.2 16.0 1.1e-11 44.4 4.6 2.7 2 0 0 2 2 2 2 GRF zinc finger AAA PF00004.24 EPR79365.1 - 5.3e-44 149.6 0.0 1e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPR79365.1 - 4.7e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPR79365.1 - 2.7e-07 30.7 0.1 5.3e-05 23.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPR79365.1 - 6.9e-07 29.4 0.0 1.8e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPR79365.1 - 4.1e-06 26.0 0.0 7.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPR79365.1 - 1.1e-05 25.1 0.2 0.00011 21.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EPR79365.1 - 6.3e-05 23.2 0.1 0.0011 19.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPR79365.1 - 0.00018 22.3 0.4 0.00055 20.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EPR79365.1 - 0.00024 20.5 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EPR79365.1 - 0.00063 19.4 0.1 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EPR79365.1 - 0.00072 19.5 0.0 0.002 18.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EPR79365.1 - 0.0016 18.5 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 EPR79365.1 - 0.0022 17.6 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPR79365.1 - 0.0022 17.8 0.0 0.0058 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPR79365.1 - 0.0028 17.2 0.0 0.0051 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EPR79365.1 - 0.0033 16.6 0.0 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EPR79365.1 - 0.0036 16.0 0.0 0.0073 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Parvo_NS1 PF01057.12 EPR79365.1 - 0.0044 15.9 0.0 0.0085 14.9 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EPR79365.1 - 0.0045 15.9 0.0 0.0077 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EPR79365.1 - 0.0047 16.3 0.4 0.11 11.9 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPR79365.1 - 0.0048 16.7 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPR79365.1 - 0.005 15.9 0.1 0.015 14.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EPR79365.1 - 0.0071 16.0 0.0 0.14 11.8 0.0 2.2 1 1 1 2 2 2 1 NACHT domain Podovirus_Gp16 PF05894.7 EPR79365.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Podovirus DNA encapsidation protein (Gp16) KaiC PF06745.8 EPR79365.1 - 0.0089 15.1 0.3 0.095 11.7 0.0 2.3 1 1 1 2 2 2 1 KaiC Arch_ATPase PF01637.13 EPR79365.1 - 0.0091 15.7 0.1 0.03 14.0 0.0 1.9 2 0 0 2 2 1 1 Archaeal ATPase Sigma54_activat PF00158.21 EPR79365.1 - 0.0091 15.4 0.0 0.031 13.7 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EPR79365.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EPR79365.1 - 0.015 14.1 0.0 0.049 12.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.7 EPR79365.1 - 0.016 14.7 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 EPR79365.1 - 0.018 14.2 0.1 0.062 12.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 EPR79365.1 - 0.03 13.9 0.2 0.17 11.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 EPR79365.1 - 0.033 14.0 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 EPR79365.1 - 0.039 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 EPR79365.1 - 0.039 13.8 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.1 EPR79365.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EPR79365.1 - 0.12 11.8 0.5 3.1 7.2 0.1 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DUF1722 PF08349.6 EPR79366.1 - 0.012 15.4 3.3 0.071 12.9 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) CDI PF02234.14 EPR79366.1 - 0.39 10.5 5.3 0.2 11.4 0.4 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor NOT2_3_5 PF04153.13 EPR79369.1 - 1e-10 41.6 0.1 1.3e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family E1-E2_ATPase PF00122.15 EPR79370.1 - 4.1e-25 88.1 0.3 1e-24 86.8 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EPR79370.1 - 1.7e-20 74.0 0.4 3.4e-20 73.0 0.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPR79370.1 - 9.4e-19 68.6 0.0 1.9e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPR79370.1 - 4.8e-05 23.2 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit P5-ATPase PF12409.3 EPR79370.1 - 0.0016 18.2 0.1 0.0043 16.9 0.1 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_3 PF08282.7 EPR79370.1 - 0.016 14.7 13.0 0.026 14.1 0.9 4.0 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Adenine_glyco PF03352.8 EPR79370.1 - 0.055 12.9 0.7 8.4 5.8 0.2 2.5 2 0 0 2 2 2 0 Methyladenine glycosylase Cation_ATPase_N PF00690.21 EPR79370.1 - 0.098 12.1 0.0 0.34 10.4 0.0 2.0 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus tRNA-synt_1 PF00133.17 EPR79371.1 - 3.2e-208 692.5 4.0 4.8e-208 691.9 2.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPR79371.1 - 1.9e-19 69.9 10.5 3.1e-19 69.2 1.3 3.5 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPR79371.1 - 7.6e-19 67.6 7.5 1.5e-06 27.1 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) NuA4 PF09340.5 EPR79372.1 - 6.7e-10 38.4 4.4 8e-10 38.2 3.0 1.0 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 BRCA-2_OB1 PF09103.5 EPR79372.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.0 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Imm35 PF15581.1 EPR79372.1 - 0.16 12.0 0.6 0.65 10.0 0.1 1.8 1 1 1 2 2 2 0 Immunity protein 35 YihI PF04220.7 EPR79372.1 - 0.2 10.9 2.2 0.23 10.8 1.5 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Enkurin PF13864.1 EPR79372.1 - 0.24 11.6 4.8 0.19 11.9 1.6 1.9 2 0 0 2 2 2 0 Calmodulin-binding DUF4519 PF15012.1 EPR79372.1 - 3.8 7.4 6.8 3.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) MIR PF02815.14 EPR79373.1 - 1.9e-06 27.5 5.7 3.1e-06 26.8 3.1 2.0 1 1 1 2 2 2 1 MIR domain RNA_pol_Rpb1_5 PF04998.12 EPR79374.1 - 6.6 5.9 6.2 11 5.1 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 BIR PF00653.16 EPR79375.1 - 7.3e-11 42.3 0.7 7.3e-11 42.3 0.5 2.7 2 1 1 3 3 3 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 EPR79375.1 - 0.044 13.5 9.7 0.026 14.2 4.9 1.8 2 1 0 2 2 2 0 C3HC zinc finger-like LRR_4 PF12799.2 EPR79376.1 - 1.9e-33 113.5 95.1 1.9e-07 30.5 1.5 13.8 5 4 11 16 16 16 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79376.1 - 2.3e-30 104.1 82.6 6.6e-07 28.9 5.4 10.8 5 4 9 14 14 14 13 Leucine rich repeat LRR_1 PF00560.28 EPR79376.1 - 2.6e-12 44.9 88.8 0.038 14.0 0.0 18.8 17 1 2 19 19 19 11 Leucine Rich Repeat LRR_7 PF13504.1 EPR79376.1 - 8.8e-09 34.1 55.4 2 8.9 0.0 16.1 17 0 0 17 17 17 4 Leucine rich repeat LRR_6 PF13516.1 EPR79376.1 - 0.00018 21.2 57.8 0.95 9.7 0.7 13.0 14 1 0 14 14 14 6 Leucine Rich repeat UCH PF00443.24 EPR79377.1 - 4.8e-43 147.2 11.4 9.8e-43 146.1 7.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR79377.1 - 7.7e-19 68.2 15.4 1.2e-17 64.2 10.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPR79377.1 - 0.0077 16.3 11.0 0.0077 16.3 7.6 2.3 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein CorA PF01544.13 EPR79378.1 - 2e-30 105.8 9.2 3e-30 105.2 6.4 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Tyrosinase PF00264.15 EPR79378.1 - 8.6 6.4 9.7 0.35 10.9 2.3 2.0 3 0 0 3 3 3 0 Common central domain of tyrosinase Kinesin PF00225.18 EPR79379.1 - 3.5e-51 173.9 17.5 3.5e-51 173.9 12.1 3.4 2 1 1 3 3 3 2 Kinesin motor domain HHH_3 PF12836.2 EPR79379.1 - 2.5e-06 27.3 0.1 8.1e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 EPR79379.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EPR79379.1 - 0.0033 17.5 0.0 0.0078 16.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain IMS_HHH PF11798.3 EPR79379.1 - 0.024 14.6 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif HHH_8 PF14716.1 EPR79379.1 - 0.04 14.0 0.1 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain TIP49 PF06068.8 EPR79380.1 - 4.9e-42 144.0 14.9 8e-33 113.7 3.0 2.2 1 1 1 2 2 2 2 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EPR79380.1 - 0.15 12.1 0.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 EPR79380.1 - 0.26 10.9 9.1 0.13 11.9 3.8 2.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Glycos_transf_2 PF00535.21 EPR79381.1 - 2.1e-28 99.0 0.5 3.1e-28 98.5 0.1 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPR79381.1 - 5.6e-09 36.1 0.0 2.4e-08 34.0 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EPR79381.1 - 3.7e-07 29.4 1.0 4.2e-07 29.3 0.2 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPR79381.1 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EPR79381.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF3479 PF11965.3 EPR79381.1 - 0.027 14.2 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) RFC1 PF08519.7 EPR79382.1 - 1.1e-25 90.1 0.9 1.1e-25 90.1 0.6 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EPR79382.1 - 3.5e-14 52.6 0.0 1.7e-13 50.4 0.0 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EPR79382.1 - 3e-13 50.1 3.6 4e-13 49.7 0.1 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPR79382.1 - 6.5e-05 23.7 1.1 0.00032 21.5 0.3 2.5 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EPR79382.1 - 0.00013 21.5 2.5 0.00044 19.8 1.7 2.0 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EPR79382.1 - 0.00021 20.4 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PTCB-BRCT PF12738.2 EPR79382.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Zeta_toxin PF06414.7 EPR79382.1 - 0.0033 16.5 0.2 0.094 11.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EPR79382.1 - 0.0057 16.8 0.2 0.018 15.1 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_16 PF13191.1 EPR79382.1 - 0.022 14.7 0.0 0.093 12.6 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain HrcA_DNA-bdg PF03444.10 EPR79382.1 - 0.023 14.1 1.1 0.023 14.1 0.7 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TyeA PF09059.5 EPR79382.1 - 0.038 13.9 0.6 0.88 9.5 0.1 2.9 2 0 0 2 2 2 0 TyeA AAA_22 PF13401.1 EPR79382.1 - 0.095 12.8 3.8 5.2 7.2 0.1 3.3 1 1 1 3 3 3 0 AAA domain NTPase_1 PF03266.10 EPR79382.1 - 0.14 11.8 4.7 1.4 8.5 0.1 3.0 1 1 2 3 3 3 0 NTPase AAA_18 PF13238.1 EPR79382.1 - 0.6 10.4 13.1 2.6 8.3 5.9 3.7 2 1 1 3 3 3 0 AAA domain DEAD PF00270.24 EPR79384.1 - 6.6e-33 113.5 0.1 1.5e-32 112.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79384.1 - 8.3e-21 73.6 1.6 8e-20 70.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.11 EPR79384.1 - 0.017 14.3 0.0 0.039 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EPR79384.1 - 0.052 12.4 0.1 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TFIID-31kDa PF02291.10 EPR79385.1 - 7.8e-29 100.0 0.2 9.4e-29 99.8 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EPR79385.1 - 9.2e-08 32.1 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EPR79385.1 - 1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EPR79385.1 - 2.8e-06 26.9 0.0 7.6e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated TAF PF02969.12 EPR79385.1 - 0.0012 18.7 0.1 0.0026 17.6 0.0 1.6 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EPR79385.1 - 0.0057 16.6 0.1 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MCR_D PF02505.9 EPR79385.1 - 0.0076 15.8 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Methyl-coenzyme M reductase operon protein D BTB PF00651.26 EPR79385.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain B56 PF01603.15 EPR79386.1 - 4.3e-14 51.9 30.4 4.3e-14 51.9 21.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Lipase_3 PF01764.20 EPR79387.1 - 3.1e-18 65.7 0.0 6.4e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EPR79387.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EPR79387.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EPR79387.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPR79387.1 - 0.039 13.7 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPR79387.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L27e PF01777.13 EPR79388.1 - 6.9e-08 32.5 1.2 1e-07 31.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPR79388.1 - 0.00029 20.4 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 KOW motif ERO1 PF04137.10 EPR79389.1 - 9.6e-21 74.1 5.0 2.1e-10 40.1 0.4 3.0 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) MutS_V PF00488.16 EPR79390.1 - 8.6e-53 179.1 6.7 1.7e-40 138.8 0.9 3.4 2 1 0 2 2 2 2 MutS domain V AAA_18 PF13238.1 EPR79390.1 - 0.011 16.0 2.8 0.019 15.2 0.4 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPR79390.1 - 0.029 14.2 1.1 0.029 14.2 0.8 2.6 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.1 EPR79390.1 - 0.036 13.6 0.0 0.086 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPR79390.1 - 0.27 11.5 19.6 2.9 8.1 13.6 2.2 1 1 0 1 1 1 0 AAA domain GLF PF03275.8 EPR79390.1 - 0.94 8.9 10.1 0.99 8.8 1.9 2.2 2 0 0 2 2 2 0 UDP-galactopyranose mutase ABC_tran PF00005.22 EPR79390.1 - 9.9 6.4 13.2 25 5.1 9.1 1.9 1 1 0 1 1 1 0 ABC transporter Spt5-NGN PF03439.8 EPR79391.1 - 3.2e-18 65.2 0.2 1.2e-17 63.4 0.2 2.1 1 1 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EPR79391.1 - 5.9e-08 33.1 5.1 9.7e-08 32.4 3.5 1.2 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EPR79391.1 - 0.0009 18.8 24.2 0.057 13.1 0.1 5.1 5 0 0 5 5 5 4 KOW motif zf-AN1 PF01428.11 EPR79392.1 - 1.3e-11 44.2 8.6 1.3e-11 44.2 5.9 1.8 2 1 0 2 2 2 1 AN1-like Zinc finger DUF2992 PF11208.3 EPR79392.1 - 1.7 8.5 5.3 13 5.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) Ribonuc_red_sm PF00268.16 EPR79393.1 - 1e-111 372.4 2.4 1.2e-111 372.2 1.7 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain APC10 PF03256.11 EPR79394.1 - 2.4e-28 99.0 0.1 3e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EPR79394.1 - 0.00027 20.7 0.0 0.00033 20.5 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain LRR_4 PF12799.2 EPR79395.1 - 1.9e-27 94.3 57.0 9.1e-06 25.1 0.9 9.9 9 2 1 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79395.1 - 5.8e-23 80.4 56.7 5.7e-06 25.9 2.8 7.7 6 1 2 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EPR79395.1 - 1.1e-13 49.0 49.1 0.4 10.8 0.0 14.3 13 1 1 14 14 14 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR79395.1 - 4.3e-08 32.0 35.7 3.6 8.2 0.3 13.6 12 1 0 12 12 12 3 Leucine rich repeat LRR_6 PF13516.1 EPR79395.1 - 0.041 13.9 44.3 1.5 9.1 0.4 11.5 13 0 0 13 13 13 0 Leucine Rich repeat LRR_1 PF00560.28 EPR79396.1 - 1e-14 52.3 29.8 0.95 9.7 0.2 10.4 9 1 0 9 9 9 8 Leucine Rich Repeat LRR_4 PF12799.2 EPR79396.1 - 4.4e-14 51.7 57.5 2.7e-05 23.6 3.0 8.5 5 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79396.1 - 1.7e-13 50.0 54.3 2.3e-06 27.2 5.6 7.7 4 2 6 10 10 10 8 Leucine rich repeat LRR_7 PF13504.1 EPR79396.1 - 1.4e-08 33.5 31.4 6 7.5 0.2 12.0 12 0 0 12 12 12 4 Leucine rich repeat LRR_6 PF13516.1 EPR79396.1 - 0.012 15.5 44.1 1.4 9.2 0.3 10.6 11 1 1 12 12 12 0 Leucine Rich repeat MS_channel PF00924.13 EPR79397.1 - 3.3e-08 33.1 4.4 3.3e-08 33.1 3.0 2.9 3 0 0 3 3 3 1 Mechanosensitive ion channel Nol1_Nop2_Fmu PF01189.12 EPR79398.1 - 1.5e-14 54.0 0.0 5.7e-14 52.1 0.0 1.9 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EPR79398.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase EFP PF01132.15 EPR79398.1 - 0.11 12.2 0.6 12 5.6 0.1 2.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain Mannosyl_trans2 PF04188.8 EPR79399.1 - 8.2e-06 24.9 9.7 1e-05 24.6 6.7 1.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) HXXEE PF13787.1 EPR79399.1 - 0.22 11.8 9.0 0.046 14.0 3.3 1.8 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Met_10 PF02475.11 EPR79400.1 - 4e-28 98.3 0.6 1.8e-27 96.2 0.4 1.9 1 1 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EPR79400.1 - 2.6e-06 26.9 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TRM PF02005.11 EPR79400.1 - 4e-06 26.0 0.1 5.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.5 EPR79400.1 - 1.3e-05 24.8 1.7 2.6e-05 23.8 1.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EPR79400.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPR79400.1 - 0.00012 21.7 4.8 0.0002 20.9 0.9 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPR79400.1 - 0.0009 18.3 1.2 0.0041 16.1 0.3 2.0 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EPR79400.1 - 0.0033 16.5 0.3 0.0045 16.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPR79400.1 - 0.0041 17.1 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EPR79400.1 - 0.054 12.8 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 WD40 PF00400.27 EPR79401.1 - 1.2e-41 139.0 4.9 5.7e-09 35.5 0.6 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPR79401.1 - 4.1e-08 32.9 1.0 0.0031 17.2 0.0 4.7 1 1 3 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EPR79401.1 - 0.018 13.1 0.2 2.2 6.3 0.2 3.2 2 1 0 2 2 2 0 Nucleoporin Nup120/160 zf-rbx1 PF12678.2 EPR79402.1 - 3.6e-29 100.6 12.1 4.3e-29 100.4 8.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPR79402.1 - 6e-16 58.0 9.7 7.3e-16 57.7 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EPR79402.1 - 2.3e-07 30.5 14.1 2.4e-06 27.2 9.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPR79402.1 - 0.00023 20.7 12.5 0.0014 18.2 8.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR79402.1 - 0.00023 20.7 11.7 0.0022 17.6 4.1 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR79402.1 - 0.0089 16.0 13.6 0.027 14.4 6.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EPR79402.1 - 0.015 15.0 5.2 0.033 13.9 3.5 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EPR79402.1 - 0.1 12.3 12.4 2.1 8.1 8.7 2.3 1 1 1 2 2 2 0 zinc-RING finger domain HTH_Tnp_Tc3_1 PF11427.3 EPR79402.1 - 0.13 11.8 0.2 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Tc3 transposase zf-Nse PF11789.3 EPR79402.1 - 0.37 10.3 4.7 0.69 9.4 3.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.1 EPR79402.1 - 0.58 10.1 10.6 1.1 9.3 7.4 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EPR79402.1 - 0.65 9.9 11.1 3.1 7.8 7.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 EPR79402.1 - 6.7 6.5 8.0 29 4.5 5.6 1.9 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain SWIRM PF04433.12 EPR79403.1 - 1.1e-25 89.5 2.8 1.7e-25 88.9 0.2 2.6 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-binding PF00249.26 EPR79403.1 - 1.7e-07 31.2 0.0 4.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPR79403.1 - 8.6e-05 22.5 0.0 0.00028 20.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain XPG_I PF00867.13 EPR79405.1 - 1.4e-08 34.6 0.0 4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 XPG I-region PseudoU_synth_1 PF01416.15 EPR79406.1 - 3.5e-21 75.5 0.7 2.1e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Spc7_N PF15402.1 EPR79406.1 - 0.12 10.3 0.2 0.17 9.8 0.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AhpC-TSA PF00578.16 EPR79407.1 - 9.1e-21 73.8 0.0 1e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPR79407.1 - 4.5e-07 29.5 0.0 5.7e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPR79408.1 - 3.6e-27 94.4 0.0 4.4e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPR79408.1 - 5.6e-11 42.1 0.0 6.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPR79409.1 - 3.7e-28 97.7 0.0 4.5e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPR79409.1 - 1.5e-11 44.0 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EPR79409.1 - 0.022 14.3 0.4 0.035 13.7 0.3 1.3 1 0 0 1 1 1 0 SCO1/SenC Syja_N PF02383.13 EPR79410.1 - 2.5e-36 125.0 11.2 1.7e-31 109.1 3.4 2.1 1 1 1 2 2 2 2 SacI homology domain DUF3811 PF11656.3 EPR79410.1 - 0.35 10.9 3.1 1 9.5 0.1 2.4 2 0 0 2 2 2 0 YjbD family (DUF3811) Metallophos PF00149.23 EPR79411.1 - 1.1e-25 90.1 4.5 1.1e-25 90.1 3.1 2.8 2 2 0 2 2 2 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.16 EPR79412.1 - 1e-25 89.7 0.0 1.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPR79412.1 - 2.2e-12 46.7 0.0 3.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin TFIIS_C PF01096.13 EPR79413.1 - 2.5e-15 55.7 11.8 4.8e-15 54.8 2.0 2.7 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) PhnA_Zn_Ribbon PF08274.7 EPR79413.1 - 0.023 14.4 5.0 0.099 12.4 0.6 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon PHD PF00628.24 EPR79413.1 - 0.029 14.0 7.4 2.3 7.9 0.1 2.5 2 0 0 2 2 2 0 PHD-finger Zn_Tnp_IS1 PF03811.8 EPR79413.1 - 0.037 13.5 0.8 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 InsA N-terminal domain DUF2296 PF10058.4 EPR79413.1 - 0.061 13.0 8.0 0.51 10.1 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-HIT PF04438.11 EPR79413.1 - 0.19 11.3 0.5 0.19 11.3 0.3 2.8 2 1 0 2 2 2 0 HIT zinc finger TF_Zn_Ribbon PF08271.7 EPR79413.1 - 0.2 10.9 0.1 0.2 10.9 0.0 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EPR79413.1 - 0.54 10.1 8.3 0.95 9.3 0.6 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_4 PF14570.1 EPR79413.1 - 0.84 9.2 0.1 0.84 9.2 0.1 3.7 2 1 1 3 3 2 0 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EPR79413.1 - 0.96 9.4 7.9 1.4 8.9 0.0 2.9 3 0 0 3 3 3 0 zinc-finger Prok-RING_1 PF14446.1 EPR79413.1 - 1.3 8.8 6.5 0.82 9.4 0.2 2.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PADR1 PF08063.7 EPR79413.1 - 1.4 8.3 8.1 4.5 6.7 0.6 2.4 2 1 0 2 2 2 0 PADR1 (NUC008) domain Sushi PF00084.15 EPR79413.1 - 1.7 9.0 6.4 0.76 10.1 0.9 2.5 1 1 1 2 2 2 0 Sushi domain (SCR repeat) CpXC PF14353.1 EPR79413.1 - 2 8.3 7.1 0.71 9.8 0.8 2.1 1 1 1 2 2 2 0 CpXC protein NinF PF05810.7 EPR79413.1 - 3.5 7.5 7.1 24 4.8 0.0 2.3 2 0 0 2 2 2 0 NinF protein HypA PF01155.14 EPR79413.1 - 4.4 7.0 8.3 6.8 6.4 0.2 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C4_Topoisom PF01396.14 EPR79413.1 - 8.9 5.9 9.7 0.65 9.5 0.9 3.3 3 2 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Transketolase_N PF00456.16 EPR79414.1 - 6.1e-107 357.2 0.0 1.2e-106 356.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPR79414.1 - 1.9e-39 134.9 0.0 3.3e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPR79414.1 - 3.1e-06 27.1 0.0 7.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EPR79414.1 - 0.00024 20.1 3.7 0.0051 15.7 0.1 2.8 2 1 1 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EPR79414.1 - 0.00029 19.6 0.1 0.00052 18.8 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EPR79414.1 - 0.00038 20.0 0.5 0.005 16.4 0.3 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain S1 PF00575.18 EPR79415.1 - 4.7e-05 23.4 0.1 0.00074 19.5 0.1 2.1 1 1 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 EPR79415.1 - 0.0065 16.3 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 NosD PF05048.8 EPR79416.1 - 0.53 9.3 5.7 0.97 8.5 4.0 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) RRM_1 PF00076.17 EPR79419.1 - 8.6e-13 47.7 0.1 1.2e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR79419.1 - 5.6e-09 35.8 0.0 7.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79419.1 - 2e-08 33.9 0.1 3.2e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPR79419.1 - 0.0043 16.8 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Beta_helix PF13229.1 EPR79419.1 - 0.033 13.9 1.0 0.039 13.7 0.7 1.1 1 0 0 1 1 1 0 Right handed beta helix region NAD_Gly3P_dh_N PF01210.18 EPR79420.1 - 4.6e-44 149.9 0.5 9e-44 148.9 0.1 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPR79420.1 - 1.2e-36 125.7 0.1 4.7e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EPR79420.1 - 4.4e-05 23.8 1.2 0.00031 21.1 0.7 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EPR79420.1 - 0.0043 16.4 0.1 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DUF4218 PF13960.1 EPR79420.1 - 0.027 13.9 0.0 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4218) UDPG_MGDP_dh_C PF03720.10 EPR79420.1 - 0.045 13.8 0.1 0.094 12.8 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Semialdhyde_dh PF01118.19 EPR79420.1 - 0.13 12.5 0.0 0.74 10.1 0.0 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 EPR79420.1 - 0.28 10.5 2.0 0.5 9.7 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain SMC_N PF02463.14 EPR79422.1 - 8.5e-42 142.8 58.0 9.8e-41 139.3 40.2 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPR79422.1 - 9.5e-15 54.6 0.0 2.7e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPR79422.1 - 0.0001 22.3 0.3 0.0001 22.3 0.2 5.4 2 1 3 5 5 5 2 AAA domain AAA_29 PF13555.1 EPR79422.1 - 0.00033 20.1 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EPR79423.1 - 0.13 11.2 27.1 0.14 11.1 18.8 1.0 1 0 0 1 1 1 0 AAA ATPase domain Orbi_VP5 PF00901.12 EPR79423.1 - 1.2 7.2 5.7 1.4 7.0 4.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 M16C_assoc PF08367.6 EPR79423.1 - 2.4 6.9 8.7 0.65 8.8 3.8 1.5 1 1 1 2 2 2 0 Peptidase M16C associated Ras PF00071.17 EPR79425.1 - 4.1e-40 136.8 0.0 4.7e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR79425.1 - 2.7e-13 50.4 0.0 4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EPR79425.1 - 1.2e-05 24.7 0.0 0.0073 15.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPR79425.1 - 0.0006 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EPR79425.1 - 0.00078 18.7 0.0 0.0013 17.9 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EPR79425.1 - 0.0047 17.0 0.0 0.072 13.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain HORMA PF02301.13 EPR79426.1 - 7.8e-28 97.3 5.9 5.2e-26 91.4 4.1 2.0 1 1 0 1 1 1 1 HORMA domain WD40 PF00400.27 EPR79427.1 - 4.6e-17 61.1 2.5 0.00015 21.5 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Pox_A21 PF05323.7 EPR79427.1 - 0.068 13.5 0.7 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A21 Protein PNK3P PF08645.6 EPR79427.1 - 0.07 12.5 0.1 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase LON PF02190.11 EPR79428.1 - 0.11 12.1 1.6 0.12 12.0 1.1 1.2 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain Proteasome PF00227.21 EPR79429.1 - 2.7e-22 78.9 0.1 3.3e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPR79429.1 - 0.071 12.4 0.0 0.071 12.4 0.0 1.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature LRR_4 PF12799.2 EPR79430.1 - 9.5e-25 85.7 36.3 1.7e-09 37.0 1.4 5.3 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79430.1 - 4.9e-18 64.6 26.7 8.2e-10 38.3 2.6 4.1 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EPR79430.1 - 9.2e-12 43.2 24.3 0.17 12.0 0.2 8.2 7 1 1 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR79430.1 - 8.9e-10 37.1 14.2 0.62 10.4 0.0 7.9 6 2 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 EPR79430.1 - 1.6e-08 33.7 19.9 0.33 11.1 0.5 8.1 3 2 4 7 7 7 2 Leucine Rich repeat LRR_9 PF14580.1 EPR79430.1 - 7.5e-06 25.6 15.1 0.00075 19.0 2.2 3.3 1 1 2 3 3 3 3 Leucine-rich repeat FNIP PF05725.7 EPR79430.1 - 0.015 15.2 6.4 2.1 8.3 0.0 5.1 4 2 0 4 4 4 0 FNIP Repeat Clr5 PF14420.1 EPR79430.1 - 3.3 7.6 4.6 0.83 9.6 0.1 2.2 3 0 0 3 3 3 0 Clr5 domain LRR_3 PF07725.7 EPR79430.1 - 4.5 7.2 10.5 6.7 6.6 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat DEAD PF00270.24 EPR79431.1 - 8.8e-33 113.1 0.3 1.9e-32 112.0 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79431.1 - 1.7e-26 91.8 0.0 5.5e-26 90.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79431.1 - 6.1e-06 26.1 1.0 4.6e-05 23.3 0.1 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPR79431.1 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.1 EPR79431.1 - 0.0019 17.3 0.0 0.0043 16.1 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EPR79431.1 - 0.0053 15.2 0.0 0.011 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Phage_integrase PF00589.17 EPR79431.1 - 0.041 13.5 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase family Cytochrom_CIII PF02085.11 EPR79431.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Class III cytochrome C family LRR_4 PF12799.2 EPR79432.1 - 1.9e-35 119.8 61.2 2.7e-08 33.2 0.4 10.0 7 2 4 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79432.1 - 7.7e-29 99.2 53.4 1.8e-08 34.0 3.2 7.8 4 3 5 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EPR79432.1 - 1.3e-14 51.9 57.6 0.095 12.7 0.1 15.4 15 0 0 15 15 15 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR79432.1 - 1.6e-13 48.4 28.6 1.5 9.3 0.0 13.9 13 0 0 13 13 13 4 Leucine rich repeat LRR_6 PF13516.1 EPR79432.1 - 0.0026 17.6 57.7 1.6 9.0 0.8 13.5 14 0 0 14 14 14 4 Leucine Rich repeat AvrB_AvrC PF05394.6 EPR79432.1 - 0.08 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Avirulence protein Peptidase_M1 PF01433.15 EPR79433.1 - 3.4e-118 395.1 5.9 5.6e-118 394.4 4.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EPR79433.1 - 6.3e-18 65.0 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily WD40 PF00400.27 EPR79434.1 - 9.4e-17 60.1 5.1 1.7e-07 30.8 0.1 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EPR79435.1 - 2.1e-15 57.0 0.0 2e-14 53.9 0.0 2.3 1 1 0 1 1 1 1 Cytidylyltransferase LSM PF01423.17 EPR79436.1 - 1.2e-17 63.2 4.3 2.4e-17 62.2 3.0 1.5 1 0 0 1 1 1 1 LSM domain DUF2969 PF11184.3 EPR79436.1 - 0.017 15.2 2.0 0.017 15.2 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2969) HTH_Tnp_1_2 PF13022.1 EPR79436.1 - 0.056 13.2 0.3 0.14 11.9 0.2 1.6 1 1 0 1 1 1 0 Helix-turn-helix of insertion element transposase ArsA_ATPase PF02374.10 EPR79437.1 - 5.4e-31 107.7 9.4 3.9e-27 95.0 6.5 3.0 1 1 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EPR79437.1 - 1.9e-13 50.2 0.6 2.5e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 EPR79437.1 - 4.4e-05 23.9 9.4 8.1e-05 23.0 6.5 1.4 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EPR79437.1 - 9.4e-05 22.3 0.1 0.00025 21.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPR79437.1 - 0.0018 17.2 0.1 0.0036 16.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 EPR79437.1 - 0.0027 17.3 0.1 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPR79437.1 - 0.0077 15.6 0.1 0.039 13.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EPR79437.1 - 0.016 14.4 0.0 0.038 13.1 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SMC_N PF02463.14 EPR79437.1 - 0.027 13.7 0.8 0.07 12.3 0.5 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EPR79437.1 - 0.028 14.7 0.2 0.028 14.7 0.1 2.4 2 2 1 3 3 3 0 AAA domain AAA_19 PF13245.1 EPR79437.1 - 0.037 13.7 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ParA PF10609.4 EPR79437.1 - 0.047 13.5 0.3 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 ParA/MinD ATPase like Spt4 PF06093.8 EPR79437.1 - 0.06 13.2 0.2 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Zeta_toxin PF06414.7 EPR79437.1 - 0.072 12.1 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EPR79437.1 - 0.093 12.2 0.3 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPR79437.1 - 0.12 12.7 1.6 0.11 12.7 0.2 1.8 2 1 0 2 2 2 0 ABC transporter AAA_26 PF13500.1 EPR79437.1 - 0.5 9.9 3.2 4.7 6.7 0.2 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EPR79437.1 - 0.75 10.6 4.1 1.4 9.7 2.8 2.1 1 1 0 1 1 1 0 AAA domain S10_plectin PF03501.10 EPR79438.1 - 6.2e-24 83.6 0.1 7.1e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain RhoGAP PF00620.22 EPR79439.1 - 5.7e-19 68.2 0.2 1e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain EpsG PF14897.1 EPR79439.1 - 0.018 14.0 6.3 0.019 13.9 0.4 2.2 2 0 0 2 2 2 0 EpsG family Acyltransferase PF01553.16 EPR79440.1 - 9.1e-19 67.1 0.0 1.4e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase RRM_1 PF00076.17 EPR79441.1 - 8.7e-27 92.5 24.3 1.7e-11 43.5 0.6 4.3 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR79441.1 - 1.7e-25 88.7 3.8 6.5e-09 35.6 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79441.1 - 5e-09 35.8 18.5 3.7e-05 23.4 1.4 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPR79441.1 - 0.36 10.6 1.9 1.7 8.4 0.1 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Mem_trans PF03547.13 EPR79441.1 - 5.4 5.2 4.8 7.3 4.7 3.3 1.2 1 0 0 1 1 1 0 Membrane transport protein Homeobox PF00046.24 EPR79442.1 - 2.1e-20 72.1 0.1 3.9e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain ubiquitin PF00240.18 EPR79442.1 - 0.046 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family Homeobox_KN PF05920.6 EPR79442.1 - 0.067 12.8 0.2 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Homeobox KN domain DEAD_2 PF06733.10 EPR79443.1 - 5.1e-37 126.9 11.4 5.1e-37 126.9 7.9 2.3 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 EPR79443.1 - 3.5e-19 69.3 0.7 8.9e-19 68.0 0.1 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EPR79443.1 - 2.1e-06 27.3 5.4 0.00096 18.6 3.0 3.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EPR79443.1 - 0.0071 15.5 1.5 2.4 7.3 0.6 2.8 2 1 0 2 2 2 2 PhoH-like protein ER_lumen_recept PF00810.13 EPR79443.1 - 0.21 12.0 2.8 0.21 12.0 0.9 1.8 2 0 0 2 2 2 0 ER lumen protein retaining receptor AAA_22 PF13401.1 EPR79443.1 - 0.41 10.7 3.2 36 4.4 2.2 2.8 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.15 EPR79444.1 - 3.4e-109 365.4 4.1 4e-109 365.2 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPR79444.1 - 1.8e-08 33.3 0.4 7e-07 28.1 0.0 2.8 2 1 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EPR79444.1 - 0.01 14.7 0.2 0.22 10.3 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Syntaxin-6_N PF09177.6 EPR79444.1 - 0.1 12.9 1.9 3 8.3 0.2 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FtsA PF14450.1 EPR79444.1 - 0.37 10.6 2.6 4.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Cell division protein FtsA Methyltransf_23 PF13489.1 EPR79445.1 - 6.7e-17 61.6 0.0 9.1e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPR79445.1 - 1.1e-13 51.4 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPR79445.1 - 2.5e-13 49.8 1.6 5.5e-13 48.7 1.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPR79445.1 - 3.1e-11 43.6 0.1 7.4e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR79445.1 - 1.1e-10 42.0 0.0 3.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPR79445.1 - 2.9e-09 37.2 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EPR79445.1 - 0.00017 20.9 0.8 0.0044 16.3 0.1 2.7 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain CMAS PF02353.15 EPR79445.1 - 0.00021 20.4 0.1 0.00049 19.2 0.0 1.6 1 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EPR79445.1 - 0.00027 20.3 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EPR79445.1 - 0.00061 19.8 0.0 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPR79445.1 - 0.0092 15.1 4.0 0.079 12.1 0.1 2.4 2 1 0 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.9 EPR79445.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DbpA PF03880.10 EPR79445.1 - 0.023 14.3 0.1 0.067 12.8 0.1 1.8 1 0 0 1 1 1 0 DbpA RNA binding domain Methyltransf_4 PF02390.12 EPR79445.1 - 0.024 13.6 0.3 0.37 9.8 0.0 2.4 2 1 0 2 2 2 0 Putative methyltransferase Pkinase PF00069.20 EPR79446.1 - 1.2e-46 158.9 0.0 9e-46 156.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79446.1 - 1.2e-18 67.1 0.0 3.4e-13 49.2 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EPR79446.1 - 1e-05 24.6 0.0 0.24 10.2 0.0 3.2 3 0 0 3 3 3 3 Kinase-like APH PF01636.18 EPR79446.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPR79446.1 - 0.022 13.8 0.1 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EPR79446.1 - 0.048 13.2 0.6 0.085 12.4 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Trehalose_PPase PF02358.11 EPR79447.1 - 9e-50 168.7 0.0 1.6e-49 167.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.16 EPR79447.1 - 3.1e-32 111.6 9.6 4.9e-32 111.0 6.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Pescadillo_N PF06732.6 EPR79448.1 - 1.7e-10 40.6 16.3 6.5e-07 28.8 8.3 2.2 1 1 1 2 2 2 2 Pescadillo N-terminus DUF4358 PF14270.1 EPR79448.1 - 0.027 14.3 0.1 0.027 14.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) ABC_tran PF00005.22 EPR79449.1 - 2.1e-35 121.9 7.0 1.5e-18 67.4 0.1 4.0 3 1 1 4 4 4 3 ABC transporter ABC_tran_2 PF12848.2 EPR79449.1 - 4.1e-20 71.3 11.7 1.2e-19 69.9 8.1 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EPR79449.1 - 1.1e-07 31.2 6.3 0.00088 18.5 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPR79449.1 - 3.1e-07 30.6 13.0 2.3e-05 24.5 0.6 5.6 2 2 2 4 4 3 2 AAA domain RNA_helicase PF00910.17 EPR79449.1 - 8.6e-07 29.1 0.2 0.072 13.2 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_29 PF13555.1 EPR79449.1 - 3.2e-06 26.5 0.5 0.00077 18.9 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EPR79449.1 - 1e-05 25.2 0.6 0.029 14.0 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EPR79449.1 - 0.00017 21.4 2.8 0.27 11.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EPR79449.1 - 0.00031 20.6 0.0 0.056 13.3 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EPR79449.1 - 0.00034 20.3 0.5 0.92 9.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPR79449.1 - 0.00046 19.3 0.0 0.092 11.8 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 EPR79449.1 - 0.00076 19.6 0.0 1.8 8.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPR79449.1 - 0.001 19.2 2.3 0.073 13.2 0.2 2.9 2 2 0 2 2 2 1 AAA domain Miro PF08477.8 EPR79449.1 - 0.002 18.6 0.7 0.25 11.8 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EPR79449.1 - 0.0037 17.6 11.1 0.0037 17.6 7.7 3.6 1 1 0 2 2 1 1 AAA domain MobB PF03205.9 EPR79449.1 - 0.0037 16.9 1.5 0.073 12.7 0.3 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EPR79449.1 - 0.005 16.2 0.0 0.36 10.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EPR79449.1 - 0.011 14.7 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EPR79449.1 - 0.012 15.0 3.3 0.017 14.6 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EPR79449.1 - 0.019 14.9 0.5 3.4 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EPR79449.1 - 0.02 15.7 11.4 3 8.7 0.0 5.2 4 1 0 4 4 4 0 AAA domain DUF258 PF03193.11 EPR79449.1 - 0.026 13.7 9.9 0.028 13.6 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EPR79449.1 - 0.031 13.7 0.2 0.76 9.2 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MCM PF00493.18 EPR79449.1 - 0.076 11.8 0.1 0.076 11.8 0.1 2.9 4 0 0 4 4 4 0 MCM2/3/5 family DUF815 PF05673.8 EPR79449.1 - 0.1 11.5 5.6 0.49 9.2 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EPR79449.1 - 0.17 11.4 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPR79449.1 - 0.22 11.2 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 EPR79449.1 - 0.44 10.0 4.9 0.36 10.3 0.3 2.8 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 EPR79449.1 - 1 8.7 10.1 0.2 11.0 0.4 3.2 4 1 0 4 4 4 0 AAA-like domain DUF3337 PF11816.3 EPR79450.1 - 0.046 13.1 0.1 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Swi3 PF07962.7 EPR79451.1 - 0.0045 16.5 0.1 0.006 16.1 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 YppF PF14178.1 EPR79451.1 - 0.021 14.3 0.4 0.088 12.3 0.3 2.0 1 1 0 1 1 1 0 YppF-like protein DUF1889 PF08986.5 EPR79451.1 - 0.065 13.4 0.1 0.076 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) DUF4473 PF14747.1 EPR79451.1 - 0.19 11.9 1.7 0.33 11.2 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4473) ABC_tran PF00005.22 EPR79452.1 - 2.3e-31 108.9 0.1 5.2e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EPR79452.1 - 2.4e-15 56.6 21.4 3.8e-15 56.0 14.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EPR79452.1 - 8.4e-10 39.0 5.9 8.4e-10 39.0 4.1 4.0 2 2 0 2 2 1 1 AAA domain SMC_N PF02463.14 EPR79452.1 - 3.6e-07 29.6 1.8 0.00079 18.7 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.10 EPR79452.1 - 0.00057 19.6 0.4 0.042 13.5 0.3 2.8 1 1 0 1 1 1 1 NTPase AAA_17 PF13207.1 EPR79452.1 - 0.0031 18.3 0.1 0.0086 16.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPR79452.1 - 0.0039 16.2 0.4 0.0039 16.2 0.3 4.0 1 1 3 4 4 2 2 AAA ATPase domain AAA_29 PF13555.1 EPR79452.1 - 0.0041 16.6 0.0 0.0098 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EPR79452.1 - 0.0048 16.9 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain KH_2 PF07650.12 EPR79452.1 - 0.0049 16.3 2.9 0.018 14.5 2.0 2.0 1 0 0 1 1 1 1 KH domain ATP-synt_ab PF00006.20 EPR79452.1 - 0.0058 16.1 0.1 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 EPR79452.1 - 0.01 15.7 0.2 0.23 11.4 0.1 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EPR79452.1 - 0.015 15.4 0.4 0.23 11.6 0.3 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPR79452.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPR79452.1 - 0.024 14.8 0.8 0.24 11.5 0.2 2.7 2 1 0 2 2 1 0 AAA domain T2SE PF00437.15 EPR79452.1 - 0.033 13.0 0.7 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EPR79452.1 - 0.1 12.0 0.6 0.82 9.0 0.1 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EPR79452.1 - 0.11 11.8 0.0 0.62 9.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EPR79452.1 - 0.23 11.7 4.0 1.1 9.5 1.6 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPR79452.1 - 0.77 9.7 4.6 5.8 6.8 3.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase ubiquitin PF00240.18 EPR79453.1 - 2.2e-35 119.8 0.7 2.5e-35 119.6 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPR79453.1 - 1.2e-20 72.9 0.7 1.3e-20 72.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPR79453.1 - 9.8e-07 28.9 0.2 3.9e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPR79453.1 - 5.9e-05 22.8 0.0 6.5e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPR79453.1 - 0.0019 18.0 0.1 0.0042 16.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPR79453.1 - 0.003 17.7 0.1 0.0036 17.4 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EPR79453.1 - 0.041 13.9 0.0 0.15 12.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EPR79453.1 - 0.046 12.0 0.7 0.59 8.3 0.2 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain PTR2 PF00854.16 EPR79454.1 - 5.8e-64 216.2 17.7 1.1e-63 215.2 12.2 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EPR79454.1 - 3.5e-19 68.7 12.7 3.5e-19 68.7 8.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EPR79454.1 - 0.065 11.3 0.2 0.11 10.5 0.1 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Ribosomal_L30 PF00327.15 EPR79455.1 - 4.2e-17 61.4 0.5 8.3e-17 60.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF106 PF01956.11 EPR79455.1 - 1.7 8.1 4.3 2.8 7.4 3.0 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF3829 PF12889.2 EPR79455.1 - 3.6 6.7 14.3 5.3 6.1 9.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) L31 PF09784.4 EPR79455.1 - 6.1 6.9 10.6 19 5.3 3.7 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Lipase3_N PF03893.11 EPR79456.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region YfzA PF14118.1 EPR79456.1 - 0.22 11.6 1.4 1.4 9.0 0.1 2.4 1 1 0 2 2 2 0 YfzA-like protein Pkinase PF00069.20 EPR79457.1 - 1.7e-47 161.8 1.8 2.5e-47 161.2 1.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79457.1 - 8.7e-22 77.4 0.0 1.4e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79457.1 - 6e-12 45.1 0.0 9.3e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPR79457.1 - 0.0099 14.9 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR79457.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L7Ae PF01248.21 EPR79458.1 - 8.6e-18 63.6 1.4 1.4e-17 62.9 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.1 EPR79458.1 - 0.065 13.2 0.2 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Methyltransf_11 PF08241.7 EPR79459.1 - 5.4e-14 52.4 0.0 9.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.3 EPR79459.1 - 1.4e-12 47.8 9.4 1.4e-12 47.8 6.5 1.7 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.1 EPR79459.1 - 2.8e-11 43.6 0.0 7.7e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPR79459.1 - 9.2e-11 41.5 0.3 1.2e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPR79459.1 - 5.1e-10 39.7 0.2 1e-09 38.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPR79459.1 - 1.6e-09 37.7 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR79459.1 - 5.3e-08 33.4 0.0 1.1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EPR79459.1 - 2e-07 30.7 1.1 0.0006 19.3 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Ubie_methyltran PF01209.13 EPR79459.1 - 4.4e-07 29.2 0.1 8.4e-07 28.3 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EPR79459.1 - 2.6e-05 23.4 0.0 5.2e-05 22.4 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EPR79459.1 - 7e-05 22.4 0.3 0.00077 19.0 0.0 2.2 3 0 0 3 3 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EPR79459.1 - 0.0014 17.8 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPR79459.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EPR79459.1 - 0.0027 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EPR79459.1 - 0.0074 15.6 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EPR79459.1 - 0.011 14.7 0.2 0.037 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.1 EPR79459.1 - 0.053 13.1 0.2 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.9 EPR79459.1 - 0.057 12.5 0.1 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.6 EPR79459.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Lactamase_B PF00753.22 EPR79461.1 - 0.00022 20.9 0.2 0.0032 17.1 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Laminin_B PF00052.13 EPR79461.1 - 0.078 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Laminin B (Domain IV) Acetyltransf_1 PF00583.19 EPR79462.1 - 1.1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPR79462.1 - 6.4e-07 29.4 0.7 2.1e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPR79462.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPR79462.1 - 0.0024 18.0 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPR79462.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Rad10 PF03834.9 EPR79464.1 - 7.3e-19 67.2 0.7 1.8e-18 65.9 0.5 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.2 EPR79464.1 - 2e-05 24.3 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EPR79464.1 - 0.0016 18.5 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 EPR79464.1 - 0.042 13.2 0.6 0.12 11.7 0.4 1.8 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain DDE_Tnp_IS1595 PF12762.2 EPR79465.1 - 1.5e-08 34.6 1.3 1.7e-08 34.4 0.9 1.0 1 0 0 1 1 1 1 ISXO2-like transposase domain DHQ_synthase PF01761.15 EPR79465.1 - 0.022 13.6 0.6 0.024 13.5 0.4 1.0 1 0 0 1 1 1 0 3-dehydroquinate synthase DDE_Tnp_IS66 PF03050.9 EPR79465.1 - 0.092 11.9 0.0 0.13 11.4 0.0 1.3 1 1 0 1 1 1 0 Transposase IS66 family YolD PF08863.5 EPR79465.1 - 1.1 9.2 6.8 1.8 8.4 2.2 2.0 2 0 0 2 2 2 0 YolD-like protein ETRAMP PF09716.5 EPR79466.1 - 2 8.4 6.1 3.1 7.8 4.2 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-RING_2 PF13639.1 EPR79467.1 - 1.8e-09 37.2 10.4 2.9e-09 36.5 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPR79467.1 - 1.4e-07 31.5 5.6 2.9e-07 30.4 3.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPR79467.1 - 0.0016 18.1 12.0 0.0027 17.4 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPR79467.1 - 0.0034 17.0 13.8 0.0054 16.3 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR79467.1 - 0.0063 16.5 13.7 0.012 15.6 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR79467.1 - 0.015 14.9 12.1 0.032 13.8 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPR79467.1 - 0.041 13.7 5.7 0.091 12.6 4.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EPR79467.1 - 0.4 10.6 15.0 2.3 8.2 10.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RCC1 PF00415.13 EPR79468.1 - 1.7e-47 159.3 11.7 3.1e-09 36.8 0.0 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPR79468.1 - 7.7e-25 85.9 15.8 2.1e-05 23.9 0.0 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Plasmodium_Vir PF05795.6 EPR79469.1 - 7.9e-06 25.3 0.3 1.1e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Herpes_gE PF02480.11 EPR79469.1 - 0.0018 16.6 0.0 0.0021 16.4 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EPR79469.1 - 0.0021 17.7 0.2 0.003 17.2 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family CD34_antigen PF06365.7 EPR79469.1 - 0.0031 17.1 0.1 0.0038 16.8 0.1 1.1 1 0 0 1 1 1 1 CD34/Podocalyxin family FAM176 PF14851.1 EPR79469.1 - 0.006 16.2 3.3 0.03 14.0 0.0 2.1 1 1 1 2 2 2 1 FAM176 family DUF2370 PF10176.4 EPR79469.1 - 0.018 14.4 0.1 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF3899 PF13038.1 EPR79469.1 - 0.027 14.6 0.3 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Zip PF02535.17 EPR79469.1 - 0.049 12.6 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4027 PF13219.1 EPR79469.1 - 0.071 12.5 0.5 0.11 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) 7tm_1 PF00001.16 EPR79469.1 - 0.073 12.1 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EVC2_like PF12297.3 EPR79469.1 - 0.11 11.1 0.0 0.17 10.4 0.0 1.3 1 1 0 1 1 1 0 Ellis van Creveld protein 2 like protein CASP_C PF08172.7 EPR79469.1 - 0.4 9.6 3.6 0.46 9.4 2.3 1.4 1 1 0 1 1 1 0 CASP C terminal DEAD PF00270.24 EPR79471.1 - 4.5e-45 153.1 0.0 1e-43 148.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79471.1 - 1.6e-28 98.4 0.1 1.2e-27 95.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79471.1 - 2.6e-05 24.1 0.1 0.0002 21.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EPR79471.1 - 0.00072 18.0 0.0 0.0075 14.7 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EPR79471.1 - 0.017 15.2 0.0 0.072 13.2 0.0 2.0 1 1 1 2 2 2 0 AAA domain PAR1 PF06521.6 EPR79472.1 - 0.22 11.0 3.2 5.5 6.5 0.1 3.1 1 1 1 3 3 3 0 PAR1 protein vMSA PF00695.14 EPR79472.1 - 2.5 7.2 6.6 35 3.4 4.7 2.0 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus TFIIF_beta PF02270.10 EPR79473.1 - 4.1e-39 135.0 4.6 6.7e-26 91.7 2.2 2.0 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit TUG-UBL1 PF11470.3 EPR79473.1 - 0.073 13.0 0.2 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 GLUT4 regulating protein TUG Ricin_B_lectin PF00652.17 EPR79474.1 - 5.2e-05 23.2 0.1 0.00014 21.9 0.0 1.8 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain Fcf1 PF04900.7 EPR79474.1 - 0.00078 19.5 4.9 0.001 19.1 2.7 1.7 1 1 0 1 1 1 1 Fcf1 RicinB_lectin_2 PF14200.1 EPR79474.1 - 0.005 17.1 0.1 0.099 13.0 0.0 2.3 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like IncA PF04156.9 EPR79474.1 - 0.0089 15.6 4.7 0.012 15.2 3.2 1.2 1 0 0 1 1 1 1 IncA protein ArsR PF09824.4 EPR79474.1 - 0.016 14.5 1.8 0.016 14.5 1.2 2.3 1 1 0 2 2 2 0 ArsR transcriptional regulator FlaC_arch PF05377.6 EPR79474.1 - 0.039 13.8 8.6 0.93 9.4 0.2 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.6 EPR79474.1 - 0.072 11.7 13.6 0.13 10.9 9.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF722 PF05263.6 EPR79474.1 - 0.1 12.7 10.1 1.8 8.6 2.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF722) Cytochrom_B562 PF07361.6 EPR79474.1 - 0.13 12.7 4.2 0.24 11.8 2.9 1.4 1 0 0 1 1 1 0 Cytochrome b562 Mnd1 PF03962.10 EPR79474.1 - 0.13 11.8 9.4 0.2 11.2 6.5 1.3 1 0 0 1 1 1 0 Mnd1 family Z1 PF10593.4 EPR79474.1 - 0.24 10.6 6.2 0.37 9.9 4.3 1.2 1 0 0 1 1 1 0 Z1 domain Prefoldin_3 PF13758.1 EPR79474.1 - 0.28 11.0 8.6 0.057 13.2 1.8 2.5 2 1 1 3 3 3 0 Prefoldin subunit DUF1160 PF06648.6 EPR79474.1 - 0.5 10.1 6.8 2.1 8.1 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1160) COG2 PF06148.6 EPR79474.1 - 0.65 9.8 8.0 4.7 7.1 1.2 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NEP PF10167.4 EPR79474.1 - 1.1 9.0 12.8 2 8.1 0.5 3.2 1 1 2 3 3 3 0 Uncharacterised conserved protein Fib_alpha PF08702.5 EPR79474.1 - 1.3 9.1 13.1 2.2 8.3 5.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prp18 PF02840.10 EPR79474.1 - 3.9 7.2 9.2 6.6 6.5 2.4 2.2 1 1 1 2 2 2 0 Prp18 domain tRNA-synt_2b PF00587.20 EPR79475.1 - 1.9e-41 141.4 0.1 4.1e-41 140.4 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPR79475.1 - 1.2e-12 47.6 0.4 3.6e-12 46.0 0.3 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EPR79475.1 - 1.7e-12 46.9 0.0 6.8e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain LRR_8 PF13855.1 EPR79477.1 - 6.3e-31 105.9 75.7 1.2e-07 31.3 6.6 8.6 5 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EPR79477.1 - 6.2e-22 76.7 100.3 7.8e-07 28.5 2.9 11.9 6 2 8 14 14 14 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79477.1 - 1.4e-09 36.6 86.8 0.091 12.8 1.4 16.2 16 1 2 18 18 18 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR79477.1 - 1.1e-05 24.8 49.7 0.43 10.9 0.1 13.1 13 0 0 13 13 13 3 Leucine rich repeat LRR_6 PF13516.1 EPR79477.1 - 0.4 10.8 0.1 0.4 10.8 0.0 13.8 14 1 1 15 15 15 0 Leucine Rich repeat Leptin PF02024.10 EPR79477.1 - 5.7 6.5 6.8 3.5 7.2 0.2 3.2 2 2 1 3 3 3 0 Leptin PseudoU_synth_1 PF01416.15 EPR79479.1 - 6.9e-15 55.3 0.3 6.1e-07 29.8 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase Exo_endo_phos PF03372.18 EPR79480.1 - 4.6e-10 39.8 0.0 5.3e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPR79480.1 - 1.7e-05 24.4 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SIS PF01380.17 EPR79481.1 - 2.5e-50 169.4 0.3 6.2e-29 100.2 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EPR79481.1 - 3.9e-25 88.3 0.0 1.2e-17 63.6 0.0 2.6 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPR79481.1 - 7.8e-24 84.1 0.0 1.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPR79481.1 - 5.2e-18 64.9 0.0 2.1e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EPR79481.1 - 9.1e-07 27.8 0.0 1.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EPR79481.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 SIS domain Pkinase PF00069.20 EPR79482.1 - 1.4e-48 165.2 1.8 1.9e-48 164.8 1.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79482.1 - 3.5e-22 78.7 0.2 1.3e-21 76.8 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79482.1 - 6.8e-05 21.9 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPR79482.1 - 0.00056 18.8 3.0 0.00096 18.0 2.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EPR79482.1 - 0.0055 15.7 0.4 0.011 14.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR79482.1 - 0.0073 16.0 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPR79482.1 - 0.022 14.3 0.7 0.052 13.1 0.5 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Chitin_synth_2 PF03142.10 EPR79483.1 - 1e-187 624.7 12.6 5.3e-94 315.4 1.7 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EPR79483.1 - 3.8e-16 59.5 0.0 1.2e-07 31.7 0.0 3.2 3 0 0 3 3 3 3 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EPR79483.1 - 1.1e-11 44.7 6.9 1.6e-08 34.5 0.1 3.3 4 1 0 4 4 4 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EPR79483.1 - 3.4e-10 39.8 0.2 0.00013 21.6 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPR79483.1 - 0.00025 20.3 0.0 0.0019 17.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Mucin PF01456.12 EPR79483.1 - 0.25 11.0 4.3 0.42 10.3 3.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_S8 PF00410.14 EPR79484.1 - 9.3e-22 77.2 0.1 1.5e-21 76.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 DDE_3 PF13358.1 EPR79485.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease AAA PF00004.24 EPR79485.1 - 0.1 12.7 0.2 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-RING_2 PF13639.1 EPR79486.1 - 0.0014 18.3 4.4 0.0014 18.3 3.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPR79486.1 - 0.0031 17.1 2.8 0.0063 16.1 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HSBP1 PF06825.7 EPR79486.1 - 0.022 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 zf-RING_5 PF14634.1 EPR79486.1 - 0.1 12.3 6.1 0.21 11.3 4.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPR79486.1 - 0.11 12.5 5.8 0.24 11.4 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 EPR79486.1 - 0.21 11.6 10.4 0.15 12.1 2.9 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) PHD PF00628.24 EPR79486.1 - 0.26 10.9 7.7 0.28 10.9 3.7 2.0 2 0 0 2 2 2 0 PHD-finger zf-C3HC4 PF00097.20 EPR79486.1 - 0.27 10.9 6.3 0.77 9.4 4.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EPR79486.1 - 0.37 10.5 7.7 1.5 8.5 3.6 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 EPR79486.1 - 0.95 9.6 7.9 1.2 9.3 4.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger GTP_EFTU PF00009.22 EPR79488.1 - 1.4e-38 132.2 0.1 2.5e-38 131.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EPR79488.1 - 1e-23 83.1 1.0 3.2e-23 81.5 0.7 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EPR79488.1 - 5.3e-08 32.8 2.0 6.8e-08 32.5 0.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPR79488.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPR79488.1 - 0.033 14.0 0.4 0.99 9.1 0.2 2.5 1 1 0 1 1 1 0 Dynamin family Zn-ribbon_8 PF09723.5 EPR79488.1 - 0.11 12.5 3.3 0.26 11.2 2.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Ribonuc_red_lgC PF02867.10 EPR79489.1 - 2.8e-207 689.5 0.0 3.8e-207 689.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EPR79489.1 - 2.8e-22 78.3 0.1 7.3e-22 76.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EPR79489.1 - 1.5e-05 25.3 0.4 5.7e-05 23.4 0.3 2.1 1 0 0 1 1 1 1 ATP cone domain DUF3969 PF13108.1 EPR79490.1 - 0.064 12.9 2.8 2.3 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) Piwi PF02171.12 EPR79492.1 - 2.1e-78 263.3 0.4 3.9e-78 262.4 0.3 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EPR79492.1 - 4.1e-24 84.3 0.0 1e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EPR79492.1 - 1.4e-06 27.5 0.0 2.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Dynamin_M PF01031.15 EPR79493.1 - 7.1e-58 195.7 13.3 5.9e-57 192.6 8.0 2.6 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EPR79493.1 - 7e-46 156.1 0.8 7e-46 156.1 0.5 2.2 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 EPR79493.1 - 3.6e-20 71.6 4.8 3.6e-20 71.6 3.3 2.4 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPR79493.1 - 0.00066 19.6 5.1 0.00072 19.4 0.7 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPR79493.1 - 0.0011 19.4 0.3 0.011 16.2 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein CBFD_NFYB_HMF PF00808.18 EPR79494.1 - 1.1e-18 66.9 2.0 2e-18 66.1 1.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR79494.1 - 4.4e-05 23.5 0.4 7.2e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EPR79494.1 - 0.081 12.6 0.1 0.32 10.7 0.1 1.8 2 0 0 2 2 2 0 Bromodomain associated Terminase_2 PF03592.11 EPR79494.1 - 0.094 13.0 1.6 0.13 12.5 1.1 1.2 1 0 0 1 1 1 0 Terminase small subunit Ribosomal_S10 PF00338.17 EPR79495.1 - 8.8e-07 28.6 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e WD40 PF00400.27 EPR79496.1 - 8.4e-48 158.6 16.9 3.2e-10 39.4 0.4 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPR79496.1 - 8e-36 123.2 5.6 8e-36 123.2 3.9 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Endonuc-dimeris PF09124.5 EPR79498.1 - 0.07 12.7 0.9 0.14 11.7 0.6 1.5 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation PEX11 PF05648.9 EPR79499.1 - 0.031 13.5 0.4 0.055 12.7 0.3 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Glypican PF01153.14 EPR79501.1 - 0.0012 17.6 0.6 0.0031 16.2 0.4 1.6 1 0 0 1 1 1 1 Glypican Ndc1_Nup PF09531.5 EPR79502.1 - 0.42 8.9 4.6 0.61 8.4 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EMP24_GP25L PF01105.19 EPR79504.1 - 3.5e-06 26.8 1.2 5.1e-06 26.3 0.8 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sec8_exocyst PF04048.9 EPR79505.1 - 1.5e-05 24.6 3.3 1.9e-05 24.2 2.1 1.6 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain Abi_C PF14355.1 EPR79508.1 - 0.083 12.8 0.0 0.23 11.4 0.0 1.8 1 1 0 1 1 1 0 Abortive infection C-terminus DUF3949 PF13133.1 EPR79509.1 - 0.071 13.3 0.9 0.26 11.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) TSP_1 PF00090.14 EPR79509.1 - 0.57 10.3 5.4 23 5.2 0.0 3.6 4 0 0 4 4 4 0 Thrombospondin type 1 domain AAA_21 PF13304.1 EPR79511.1 - 1.7 8.5 13.4 5.8 6.7 9.2 1.8 1 1 0 1 1 1 0 AAA domain TLC PF03219.9 EPR79512.1 - 7.1e-60 202.8 34.2 3.6e-58 197.2 23.7 2.0 1 1 0 1 1 1 1 TLC ATP/ADP transporter DNA_ligase_A_M PF01068.16 EPR79513.1 - 0.028 13.7 0.5 0.029 13.7 0.4 1.0 1 0 0 1 1 1 0 ATP dependent DNA ligase domain MgtE PF01769.11 EPR79516.1 - 2.7e-08 34.1 34.4 2.5e-06 27.8 7.1 3.7 2 1 2 4 4 4 2 Divalent cation transporter RNA_pol_Rpb1_5 PF04998.12 EPR79518.1 - 5e-79 265.4 4.2 5e-79 265.4 2.9 3.0 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPR79518.1 - 3.6e-59 199.4 3.1 1.5e-58 197.3 0.0 2.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPR79518.1 - 2e-26 92.6 0.6 2e-26 92.6 0.4 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPR79518.1 - 4.9e-21 74.4 0.6 4.9e-21 74.4 0.4 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EPR79518.1 - 1.6e-19 70.3 8.0 1.6e-19 70.3 5.6 3.6 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 BCIP PF13862.1 EPR79520.1 - 2.3e-06 27.2 0.1 2.3e-06 27.2 0.1 3.7 2 1 0 2 2 2 1 p21-C-terminal region-binding protein Homeobox_KN PF05920.6 EPR79521.1 - 9.1e-19 66.8 0.8 2.1e-18 65.7 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPR79521.1 - 2.3e-10 39.9 3.8 1.3e-08 34.3 0.1 3.0 3 1 1 4 4 4 2 Homeobox domain YjgP_YjgQ PF03739.9 EPR79521.1 - 0.031 13.0 2.1 0.041 12.6 1.5 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Phage_GP20 PF06810.6 EPR79521.1 - 0.2 11.0 8.0 0.14 11.5 1.8 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF489 PF04356.7 EPR79521.1 - 1.1 8.8 4.1 1 8.8 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Homeobox_KN PF05920.6 EPR79522.1 - 1.2e-15 56.9 0.5 2.7e-15 55.7 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPR79522.1 - 2.3e-09 36.7 0.7 4.8e-09 35.7 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EPR79522.1 - 0.12 11.4 0.1 0.62 9.1 0.0 2.2 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Pkinase PF00069.20 EPR79523.1 - 1e-23 83.8 5.3 5.3e-15 55.2 0.6 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79523.1 - 4.9e-17 61.8 1.0 4e-14 52.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CutA1 PF03091.10 EPR79524.1 - 2.3e-22 78.5 4.7 2.6e-22 78.3 3.3 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein tRNA_lig_kinase PF08303.6 EPR79524.1 - 0.0021 17.9 0.9 0.003 17.4 0.4 1.5 1 1 1 2 2 2 1 tRNA ligase kinase domain Flt3_lig PF02947.9 EPR79524.1 - 0.0024 17.7 0.2 0.0028 17.5 0.1 1.1 1 0 0 1 1 1 1 flt3 ligand DEP PF00610.16 EPR79524.1 - 0.038 13.7 0.2 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2175 PF09943.4 EPR79525.1 - 0.02 14.9 3.5 0.02 14.9 2.4 4.4 3 2 2 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2175) Fer2 PF00111.22 EPR79527.1 - 1.4e-09 37.5 0.0 1.6e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nbl1_Borealin_N PF10444.4 EPR79527.1 - 0.00069 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Ribosomal_L13 PF00572.13 EPR79528.1 - 3.6e-19 69.0 2.0 4.2e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L13 MRP-S35 PF10246.4 EPR79528.1 - 0.042 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 TP53IP5 PF15331.1 EPR79528.1 - 0.046 13.6 5.0 1.9 8.3 2.5 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Ribosomal_L32e PF01655.13 EPR79529.1 - 2e-42 143.6 0.2 2.4e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 TPR_2 PF07719.12 EPR79530.1 - 4.2e-09 35.6 12.5 0.023 14.6 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPR79530.1 - 1.1e-07 31.1 20.6 0.0014 18.1 0.4 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EPR79530.1 - 6e-06 25.8 14.8 6.6e-05 22.4 0.9 5.0 3 1 1 4 4 4 1 TPR repeat TPR_12 PF13424.1 EPR79530.1 - 1.1e-05 25.2 9.1 0.77 9.7 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPR79530.1 - 1.5e-05 24.4 22.5 0.13 12.1 0.5 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPR79530.1 - 8e-05 22.9 0.1 0.85 9.9 0.0 3.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPR79530.1 - 8.5e-05 22.0 0.1 41 4.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPR79530.1 - 0.12 12.6 0.0 0.12 12.6 0.0 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPR79530.1 - 0.14 12.1 0.5 13 5.9 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 EPR79531.1 - 0.0011 18.8 0.0 0.012 15.5 0.0 2.0 1 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPR79531.1 - 0.0018 17.2 0.5 0.037 12.9 0.1 2.4 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPR79531.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EPR79531.1 - 0.027 13.9 3.2 0.15 11.4 0.1 2.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Myosin_head PF00063.16 EPR79532.1 - 9.8e-88 294.9 58.8 1e-86 291.5 31.4 4.7 2 2 0 2 2 2 1 Myosin head (motor domain) T2SE PF00437.15 EPR79532.1 - 0.041 12.7 1.1 0.14 10.9 0.1 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EPR79532.1 - 0.05 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EPR79532.1 - 0.32 11.3 0.0 0.32 11.3 0.0 4.4 3 1 0 4 4 4 0 ABC transporter A_deaminase PF00962.17 EPR79534.1 - 2.1e-79 266.8 0.3 3.5e-79 266.1 0.1 1.5 2 0 0 2 2 2 1 Adenosine/AMP deaminase Birna_VP3 PF01767.11 EPR79535.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP3 protein Pox_A3L PF05288.6 EPR79536.1 - 1.5 8.6 10.0 0.26 11.0 2.4 2.6 3 0 0 3 3 3 0 Poxvirus A3L Protein Arch_ATPase PF01637.13 EPR79537.1 - 0.00063 19.5 7.4 0.00076 19.2 5.1 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EPR79537.1 - 0.0015 18.6 1.6 0.0068 16.5 1.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPR79537.1 - 0.021 14.2 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPR79537.1 - 0.036 14.5 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein NACHT PF05729.7 EPR79537.1 - 0.086 12.4 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 NACHT domain MS_channel PF00924.13 EPR79538.1 - 8.2e-14 51.4 3.6 1.5e-13 50.5 2.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPR79538.1 - 2e-05 23.5 0.3 8.1e-05 21.6 0.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EPR79538.1 - 3.9e-05 23.1 0.7 8.6e-05 22.0 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPR79538.1 - 0.00017 21.1 0.5 0.00091 18.9 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EPR79538.1 - 0.00074 18.7 0.1 0.0019 17.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EPR79538.1 - 0.0022 18.1 0.6 0.0066 16.5 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair RseC_MucC PF04246.7 EPR79538.1 - 5.8 6.4 6.3 13 5.3 0.9 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC SNARE PF05739.14 EPR79539.1 - 1.8e-12 46.7 7.6 2.2e-12 46.4 1.5 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EPR79539.1 - 9.8e-06 25.6 0.7 9.8e-06 25.6 0.5 2.8 2 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EPR79539.1 - 0.0003 20.3 6.3 0.0003 20.3 4.4 1.8 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 EPR79539.1 - 0.0011 18.5 2.2 0.0011 18.5 1.5 1.6 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain T2SF PF00482.18 EPR79539.1 - 0.0068 16.3 0.4 0.046 13.6 0.1 2.4 2 1 0 2 2 2 1 Type II secretion system (T2SS), protein F Katanin_con80 PF13925.1 EPR79539.1 - 0.26 11.0 4.9 0.36 10.5 0.2 2.8 2 1 1 3 3 3 0 con80 domain of Katanin DUF1664 PF07889.7 EPR79539.1 - 0.57 9.9 11.3 0.6 9.9 2.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) AATF-Che1 PF13339.1 EPR79539.1 - 0.72 10.0 5.5 0.49 10.5 0.5 2.6 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Carbpep_Y_N PF05388.6 EPR79539.1 - 0.92 9.6 6.5 4.5 7.4 0.1 2.6 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide GP41 PF00517.12 EPR79539.1 - 1 8.8 11.7 0.074 12.5 2.3 3.0 2 2 1 3 3 3 0 Retroviral envelope protein Syntaxin-6_N PF09177.6 EPR79539.1 - 1.5 9.3 9.7 9.3 6.7 1.6 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PEX11 PF05648.9 EPR79539.1 - 1.9 7.7 7.1 0.28 10.4 1.1 2.1 2 1 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2203 PF09969.4 EPR79539.1 - 1.9 8.7 7.4 4.3 7.5 0.5 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Shisa PF13908.1 EPR79539.1 - 2.1 8.5 4.5 0.63 10.2 1.2 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2321 PF10083.4 EPR79539.1 - 2.4 7.6 8.9 1.9 7.9 2.2 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Imm5 PF14423.1 EPR79539.1 - 4 7.0 8.4 0.42 10.2 2.1 2.0 2 1 1 3 3 3 0 Immunity protein Imm5 SNARE PF05739.14 EPR79540.1 - 9.6e-11 41.2 2.8 2.6e-10 39.8 1.9 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EPR79540.1 - 2.7e-05 24.2 8.9 2.7e-05 24.2 6.2 3.1 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EPR79540.1 - 0.0071 15.9 1.9 0.0071 15.9 1.3 1.8 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4199 PF13858.1 EPR79540.1 - 0.014 15.3 2.0 0.014 15.3 1.4 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) FlaG PF03646.10 EPR79540.1 - 0.2 11.8 8.9 0.37 10.9 0.4 2.7 2 1 0 2 2 2 0 FlaG protein Abi_C PF14355.1 EPR79540.1 - 0.22 11.4 2.3 0.36 10.7 0.2 2.3 2 0 0 2 2 2 0 Abortive infection C-terminus Trp_repressor PF01371.14 EPR79540.1 - 0.34 10.8 4.4 0.3 11.0 0.4 2.6 2 1 1 3 3 3 0 Trp repressor protein Katanin_con80 PF13925.1 EPR79540.1 - 0.63 9.7 12.6 0.04 13.6 1.7 2.9 1 1 2 3 3 3 0 con80 domain of Katanin Vac_Fusion PF02346.11 EPR79540.1 - 0.96 8.9 6.2 3.4 7.1 0.5 3.3 3 0 0 3 3 3 0 Chordopoxvirus fusion protein PRANC PF09372.5 EPR79540.1 - 8.2 6.4 14.9 0.36 10.8 3.1 3.2 2 2 1 3 3 3 0 PRANC domain SNARE PF05739.14 EPR79541.1 - 9.8e-10 37.9 4.4 1.6e-09 37.3 0.2 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPR79541.1 - 0.00094 19.3 6.1 0.00094 19.3 4.2 2.8 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EPR79541.1 - 0.0052 16.3 4.8 0.0052 16.3 3.3 2.0 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1371 PF07115.6 EPR79541.1 - 0.047 13.8 0.3 0.047 13.8 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1371) DUF3708 PF12501.3 EPR79541.1 - 0.19 11.5 0.2 4.9 6.9 0.0 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Med7 PF05983.6 EPR79541.1 - 0.59 9.8 12.0 0.07 12.9 2.6 2.3 2 0 0 2 2 2 0 MED7 protein Syntaxin_2 PF14523.1 EPR79541.1 - 1.6 8.7 21.3 0.85 9.6 5.9 3.1 2 2 0 2 2 2 0 Syntaxin-like protein PRANC PF09372.5 EPR79541.1 - 1.7 8.6 17.9 1.2 9.1 2.6 3.0 3 1 0 3 3 3 0 PRANC domain Transketolase_N PF00456.16 EPR79542.1 - 6.5e-91 304.5 0.0 9.7e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPR79542.1 - 3.9e-36 124.1 0.0 5.2e-35 120.5 0.0 2.3 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EPR79542.1 - 8.8e-06 24.8 0.2 0.0032 16.4 0.0 2.8 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EPR79542.1 - 0.00027 19.7 0.3 0.00043 19.1 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EPR79542.1 - 0.00055 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EPR79542.1 - 0.00094 18.7 0.6 0.0066 16.0 0.0 2.4 1 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ras PF00071.17 EPR79543.1 - 6.6e-50 168.6 0.1 7.9e-50 168.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR79543.1 - 3.1e-11 43.8 0.1 8.7e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPR79543.1 - 1.6e-09 37.2 0.1 2e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPR79543.1 - 0.00012 21.2 0.1 0.00053 19.2 0.0 1.9 1 1 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPR79543.1 - 0.00033 20.1 0.3 0.0017 17.7 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EPR79543.1 - 0.017 14.8 0.8 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 EPR79543.1 - 0.021 14.7 0.1 0.035 14.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase FANCI_S2 PF14676.1 EPR79543.1 - 0.052 13.4 0.1 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 FANCI solenoid 2 MutL_C PF08676.6 EPR79544.1 - 1.4e-12 47.4 0.3 2.4e-11 43.4 0.1 2.0 1 1 1 2 2 2 2 MutL C terminal dimerisation domain DUF4479 PF14794.1 EPR79544.1 - 0.091 12.3 0.3 0.091 12.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) PspA_IM30 PF04012.7 EPR79545.1 - 0.019 14.3 5.4 0.03 13.6 3.7 1.3 1 0 0 1 1 1 0 PspA/IM30 family Phage_lysis PF03245.8 EPR79545.1 - 0.3 11.0 2.9 0.59 10.1 2.0 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein BOP1NT PF08145.7 EPR79545.1 - 2.6 7.6 14.6 0.058 13.1 3.9 2.2 2 0 0 2 2 2 0 BOP1NT (NUC169) domain GLE1 PF07817.8 EPR79545.1 - 7.9 5.3 13.4 0.069 12.0 3.1 1.8 2 0 0 2 2 2 0 GLE1-like protein Ribosomal_L11_N PF03946.9 EPR79546.1 - 2.3e-12 46.1 0.4 6.8e-12 44.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPR79546.1 - 4.5e-05 23.5 1.2 0.00017 21.6 0.3 2.0 1 1 1 2 2 2 1 Ribosomal protein L11, RNA binding domain GTP_EFTU_D4 PF14578.1 EPR79546.1 - 0.13 11.8 4.4 1.6 8.4 0.2 2.6 2 1 0 2 2 2 0 Elongation factor Tu domain 4 NMT PF01233.14 EPR79547.1 - 2e-39 134.8 0.5 2e-39 134.8 0.3 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EPR79547.1 - 6.5e-29 100.6 5.2 1.6e-28 99.3 3.6 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EPR79547.1 - 0.00031 20.5 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain ATG27 PF09451.5 EPR79548.1 - 0.16 11.2 1.6 0.23 10.6 1.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 Peptidase_C97 PF05903.9 EPR79549.1 - 4.6e-28 97.8 1.5 5.6e-28 97.6 1.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EPR79549.1 - 0.057 13.3 0.2 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase AmoC PF04896.7 EPR79549.1 - 0.066 12.2 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C GTP_EFTU PF00009.22 EPR79551.1 - 4.6e-38 130.5 0.0 6.1e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPR79551.1 - 2.3e-18 66.1 0.2 7.1e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPR79551.1 - 3.6e-08 33.3 0.3 9.2e-08 32.0 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.7 EPR79551.1 - 0.012 14.7 0.0 0.038 13.1 0.0 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Peptidase_M23 PF01551.17 EPR79551.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M23 Miro PF08477.8 EPR79551.1 - 0.022 15.2 0.0 0.082 13.4 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EPR79551.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase KH_1 PF00013.24 EPR79552.1 - 3.4e-05 23.4 0.2 8e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EPR79552.1 - 0.0047 16.5 0.2 0.013 15.1 0.1 1.8 1 0 0 1 1 1 1 KH domain CCDC144C PF14915.1 EPR79552.1 - 0.09 11.6 3.5 0.19 10.6 0.7 2.0 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Plasmid_Txe PF06769.8 EPR79552.1 - 0.65 9.8 5.1 3.2 7.6 0.1 2.6 2 1 1 3 3 3 0 Plasmid encoded toxin Txe SAC3_GANP PF03399.11 EPR79553.1 - 9.4e-25 87.3 9.8 1.5e-24 86.7 6.8 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CCDC92 PF14916.1 EPR79554.1 - 0.004 16.6 0.1 0.004 16.6 0.1 4.1 4 0 0 4 4 4 1 Coiled-coil domain of unknown function Death PF00531.17 EPR79554.1 - 0.01 15.5 1.0 8.2 6.2 0.0 3.3 2 0 0 2 2 2 0 Death domain Reo_sigmaC PF04582.7 EPR79554.1 - 0.03 13.5 6.4 0.063 12.4 0.2 2.9 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Uds1 PF15456.1 EPR79554.1 - 0.074 13.0 0.2 0.074 13.0 0.1 5.3 2 1 1 4 4 4 0 Up-regulated During Septation IncA PF04156.9 EPR79554.1 - 3.3 7.2 64.4 0.02 14.4 11.2 5.4 2 2 4 6 6 6 0 IncA protein Pkinase PF00069.20 EPR79555.1 - 4.9e-64 215.9 0.0 5.7e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79555.1 - 4.7e-33 114.3 0.0 5.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79555.1 - 8.7e-08 31.4 0.0 1.4e-06 27.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like DUF234 PF03008.9 EPR79556.1 - 0.0036 17.3 1.6 0.0074 16.3 1.1 1.5 1 0 0 1 1 1 1 Archaea bacterial proteins of unknown function Ribosomal_L4 PF00573.17 EPR79557.1 - 1.6e-34 119.0 0.2 2.6e-34 118.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPR79557.1 - 0.00034 20.4 0.1 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain TPR_11 PF13414.1 EPR79558.1 - 8.7e-06 25.3 6.5 0.00088 18.8 0.1 3.8 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EPR79558.1 - 0.00013 21.6 2.2 0.68 9.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPR79558.1 - 0.0005 19.9 3.6 0.12 12.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPR79558.1 - 0.025 15.2 0.0 0.048 14.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPR79558.1 - 0.029 14.1 8.5 0.092 12.5 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPR79558.1 - 0.22 11.1 12.6 1.6 8.4 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat SRP19 PF01922.12 EPR79559.1 - 3.9e-15 56.2 0.8 6.3e-15 55.5 0.5 1.5 1 1 0 1 1 1 1 SRP19 protein Hist_deacetyl PF00850.14 EPR79560.1 - 1.2e-69 235.0 0.1 1.8e-69 234.4 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain AGT PF11440.3 EPR79561.1 - 0.032 13.0 0.3 0.035 12.9 0.2 1.0 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Peptidase_M16 PF00675.15 EPR79561.1 - 0.067 12.9 0.9 0.084 12.6 0.6 1.1 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Spy1 PF11357.3 EPR79561.1 - 0.11 12.6 0.3 0.26 11.3 0.1 1.6 1 1 1 2 2 2 0 Cell cycle regulatory protein Microtub_assoc PF07989.6 EPR79561.1 - 0.49 10.2 12.5 1.1 9.1 2.2 2.3 1 1 1 2 2 2 0 Microtubule associated Casc1 PF12366.3 EPR79562.1 - 5.1 6.5 10.4 0.25 10.8 0.6 2.6 2 1 1 3 3 3 0 Cancer susceptibility candidate 1 zf-ZPR1 PF03367.8 EPR79563.1 - 2.4e-05 23.5 2.9 2.7e-05 23.3 1.3 1.6 1 1 1 2 2 2 1 ZPR1 zinc-finger domain N-glycanase_N PF09112.5 EPR79563.1 - 0.047 13.0 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal GcpE PF04551.9 EPR79563.1 - 0.061 12.1 0.2 0.079 11.7 0.2 1.2 1 0 0 1 1 1 0 GcpE protein V-set_CD47 PF08204.6 EPR79563.1 - 0.5 10.1 6.2 0.56 9.9 3.4 1.7 1 1 0 1 1 1 0 CD47 immunoglobulin-like domain GDPD PF03009.12 EPR79564.1 - 4.3e-35 121.4 0.0 1.3e-33 116.6 0.0 2.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EPR79564.1 - 0.0079 16.3 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Far-17a_AIG1 PF04750.9 EPR79565.1 - 1.1e-23 83.4 15.5 1.5e-23 83.0 10.8 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF2768 PF10966.3 EPR79565.1 - 3.2 7.9 12.4 0.095 12.8 1.3 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2768) MCM PF00493.18 EPR79566.1 - 2.3e-133 444.1 2.4 3e-133 443.7 1.7 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EPR79566.1 - 4e-06 26.1 0.0 0.0032 16.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 EPR79566.1 - 1.2e-05 25.7 4.0 0.011 16.1 0.6 3.1 1 1 1 2 2 2 2 MCM N-terminal domain AAA_5 PF07728.9 EPR79566.1 - 0.00026 20.7 0.0 0.00064 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPR79566.1 - 0.025 14.1 0.0 0.095 12.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EPR79566.1 - 0.027 14.8 0.2 0.091 13.1 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI YL1_C PF08265.6 EPR79567.1 - 1.5e-13 50.0 0.7 2.8e-13 49.1 0.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 EPR79567.1 - 0.0011 18.5 0.3 0.0019 17.7 0.2 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF3905 PF13045.1 EPR79567.1 - 0.082 12.6 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) Erf4 PF10256.4 EPR79568.1 - 3.3e-05 23.7 3.0 0.00015 21.6 0.4 1.9 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family Mei4 PF13971.1 EPR79568.1 - 0.011 14.6 0.2 0.013 14.5 0.1 1.0 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Phasin PF05597.6 EPR79569.1 - 0.00024 20.8 16.6 0.32 10.7 0.2 3.5 2 1 0 3 3 3 3 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 EPR79569.1 - 0.0027 18.0 0.9 1.9 8.9 0.0 3.5 2 1 2 4 4 4 1 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 EPR79569.1 - 0.009 16.0 23.2 0.082 12.9 1.5 3.0 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Acyl-CoA_dh_C PF12806.2 EPR79569.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like GED PF02212.13 EPR79569.1 - 0.064 13.1 4.8 0.2 11.5 0.0 3.5 3 2 1 4 4 3 0 Dynamin GTPase effector domain DUF1810 PF08837.6 EPR79569.1 - 0.065 12.8 0.1 0.39 10.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1810) HK97-gp10_like PF04883.7 EPR79569.1 - 0.18 12.7 8.2 0.24 12.3 0.1 3.6 3 1 1 4 4 4 0 Bacteriophage HK97-gp10, putative tail-component Methyltransf_32 PF13679.1 EPR79569.1 - 0.27 10.9 1.5 0.75 9.4 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain AKNA PF12443.3 EPR79569.1 - 1.5 8.8 9.4 0.13 12.2 1.1 3.0 3 0 0 3 3 3 0 AT-hook-containing transcription factor DUF1323 PF07037.6 EPR79569.1 - 1.7 8.8 7.0 2.6 8.2 0.1 3.6 1 1 2 4 4 4 0 Putative transcription regulator (DUF1323) Nbl1_Borealin_N PF10444.4 EPR79569.1 - 2 7.8 8.5 0.23 10.8 0.7 3.2 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal CK2S PF15011.1 EPR79569.1 - 2.4 7.9 8.0 0.62 9.8 0.7 2.8 2 1 1 3 3 3 0 Casein Kinase 2 substrate Peptidase_M41 PF01434.13 EPR79569.1 - 2.5 7.5 16.3 2.6 7.4 0.4 3.6 1 1 1 3 3 3 0 Peptidase family M41 Mer2 PF09074.5 EPR79569.1 - 5.2 6.9 36.6 2.4 8.0 8.3 3.2 1 1 2 3 3 3 0 Mer2 Peptidase_M75 PF09375.5 EPR79569.1 - 7.2 5.8 9.4 12 5.0 1.4 3.0 1 1 2 3 3 3 0 Imelysin GIDA PF01134.17 EPR79569.1 - 9.7 4.9 12.7 1.4 7.7 0.8 2.6 1 1 0 2 2 2 0 Glucose inhibited division protein A ABC2_membrane PF01061.19 EPR79570.1 - 1e-26 93.4 29.3 1e-26 93.4 20.3 2.2 2 0 0 2 2 2 1 ABC-2 type transporter Nodulin_late PF07127.6 EPR79570.1 - 0.69 10.0 0.1 0.69 10.0 0.1 3.4 4 0 0 4 4 4 0 Late nodulin protein DUF4260 PF14079.1 EPR79570.1 - 6.1 6.7 13.7 0.078 12.7 3.3 2.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4260) Ribosomal_S26e PF01283.14 EPR79571.1 - 8.1e-42 142.0 9.6 8.8e-42 141.9 6.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_21 PF14697.1 EPR79571.1 - 0.022 14.5 0.2 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain DNA_pol_B_3 PF08408.5 EPR79571.1 - 0.028 14.2 0.4 0.031 14.1 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B viral insert Fer4_10 PF13237.1 EPR79571.1 - 0.044 13.5 1.1 0.088 12.6 0.8 1.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Ribosomal_S14 PF00253.16 EPR79571.1 - 2.5 7.5 7.1 0.7 9.3 2.7 1.7 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Viral_NABP PF05515.6 EPR79571.1 - 3 8.1 5.5 0.73 10.1 0.8 2.0 1 1 1 2 2 2 0 Viral nucleic acid binding TPR_1 PF00515.23 EPR79572.1 - 1.4e-20 71.9 21.8 0.00026 20.4 0.2 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 EPR79572.1 - 5.7e-18 63.3 15.7 0.0027 17.4 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EPR79572.1 - 6.6e-17 60.9 16.6 2.4e-05 23.8 0.1 6.2 4 1 2 6 6 6 5 TPR repeat TPR_7 PF13176.1 EPR79572.1 - 2.6e-11 42.4 4.7 0.19 11.6 0.0 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPR79572.1 - 5.4e-11 41.4 24.4 0.032 13.9 0.4 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPR79572.1 - 3.8e-10 39.5 6.6 0.046 13.6 0.0 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EPR79572.1 - 6.2e-06 26.2 1.0 6.2e-06 26.2 0.7 5.6 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EPR79572.1 - 2.8e-05 23.9 8.5 0.00051 20.0 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPR79572.1 - 2.8e-05 24.6 0.0 2.1 9.1 0.0 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPR79572.1 - 5.2e-05 23.5 0.0 2.7 8.8 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPR79572.1 - 0.00048 20.3 0.2 18 5.7 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EPR79572.1 - 0.0011 18.7 3.0 1.3 8.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4052 PF13261.1 EPR79572.1 - 0.0013 18.2 1.6 0.0014 18.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4052) TPR_6 PF13174.1 EPR79572.1 - 0.005 17.2 8.2 9.7 6.9 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPR79572.1 - 0.068 13.1 0.1 32 4.6 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 EPR79572.1 - 0.071 12.1 1.2 0.56 9.2 0.0 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EPR79573.1 - 6.5e-38 130.0 0.3 6.5e-38 130.0 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPR79573.1 - 5e-20 71.5 0.5 1.5e-19 70.0 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EPR79573.1 - 2.4e-06 27.4 0.2 8.3e-06 25.7 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L2_C PF03947.13 EPR79573.1 - 0.074 12.8 0.4 0.54 10.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain DUF202 PF02656.10 EPR79574.1 - 3.6e-13 49.5 0.6 3.6e-13 49.5 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) BNR_assoc_N PF14873.1 EPR79574.1 - 0.048 13.4 3.2 0.099 12.4 2.2 1.6 1 1 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase EnY2 PF10163.4 EPR79575.1 - 2e-06 27.6 0.1 2.6e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF4261 PF14080.1 EPR79575.1 - 0.032 14.0 0.4 0.094 12.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4261) AAA_assoc PF14363.1 EPR79575.1 - 0.057 13.4 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA ER_lumen_recept PF00810.13 EPR79576.1 - 4.3e-46 157.0 13.1 7.9e-46 156.1 9.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPR79576.1 - 0.00075 19.0 11.8 0.22 11.0 0.6 3.8 2 1 1 3 3 3 3 PQ loop repeat WD40 PF00400.27 EPR79577.1 - 6.9e-16 57.4 10.7 6.9e-07 28.9 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EPR79577.1 - 0.0076 14.4 0.1 0.011 13.8 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CNH PF00780.17 EPR79577.1 - 0.046 13.1 0.1 7.6 5.8 0.0 2.2 1 1 1 2 2 2 0 CNH domain Coatomer_WDAD PF04053.9 EPR79577.1 - 0.088 11.5 0.1 1.1 7.9 0.0 2.2 1 1 0 1 1 1 0 Coatomer WD associated region Ricin_B_lectin PF00652.17 EPR79578.1 - 0.17 11.8 2.4 0.26 11.3 0.2 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain HlyIII PF03006.15 EPR79579.1 - 6.7e-29 100.8 22.1 8.4e-29 100.5 15.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related ABC_tran PF00005.22 EPR79580.1 - 1.4e-12 48.1 0.4 1.6e-12 47.8 0.3 1.1 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EPR79580.1 - 3.3e-06 26.3 0.4 6e-06 25.5 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EPR79580.1 - 0.0018 18.2 1.0 0.0026 17.7 0.7 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EPR79580.1 - 0.0036 17.6 3.6 0.0062 16.8 2.5 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EPR79580.1 - 0.0073 15.8 0.3 0.014 14.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EPR79580.1 - 0.0091 15.0 5.2 0.011 14.8 3.6 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPR79580.1 - 0.029 15.2 0.0 0.036 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EPR79580.1 - 0.038 13.5 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPR79580.1 - 0.063 12.3 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EPR79580.1 - 0.063 13.1 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPR79580.1 - 0.07 13.4 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPR79580.1 - 0.079 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EPR79580.1 - 0.088 13.3 0.1 0.18 12.3 0.1 1.5 1 1 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EPR79580.1 - 0.11 12.4 0.8 0.18 11.7 0.4 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EPR79580.1 - 0.12 11.7 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 EPR79580.1 - 0.12 12.1 1.2 0.2 11.4 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EPR79580.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 EPR79581.1 - 5.7e-16 59.4 15.2 5.7e-16 59.4 10.5 7.1 1 1 3 4 4 4 1 AAA domain SMC_N PF02463.14 EPR79581.1 - 6.3e-11 41.9 68.6 4.9e-10 39.0 47.6 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPR79581.1 - 1.2e-06 27.8 0.6 2.5e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EPR79581.1 - 1.3e-05 25.3 13.4 1.3e-05 25.3 9.3 5.2 1 1 4 5 5 5 1 AAA domain AAA_13 PF13166.1 EPR79581.1 - 0.00017 20.1 0.2 0.00017 20.1 0.1 5.7 2 2 2 5 5 5 2 AAA domain RSN1_TM PF13967.1 EPR79581.1 - 0.081 12.4 0.3 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport DEAD PF00270.24 EPR79582.1 - 1.3e-41 141.8 0.3 1e-40 138.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79582.1 - 5.2e-24 83.9 0.0 2.3e-23 81.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79582.1 - 1.8e-07 31.1 0.1 1.8e-07 31.1 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EPR79583.1 - 1.5e-22 80.2 3.2 2.4e-22 79.6 2.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR79583.1 - 1.1e-16 61.7 4.1 4.5e-16 59.7 2.8 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPR79583.1 - 1.4e-07 31.8 0.9 3.6e-07 30.4 0.6 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EPR79583.1 - 5.6e-06 26.1 0.1 5.6e-06 26.1 0.0 2.5 1 1 2 3 3 3 1 NTPase RNA_helicase PF00910.17 EPR79583.1 - 1.3e-05 25.3 0.4 2.4e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 RNA helicase SKI PF01202.17 EPR79583.1 - 3.7e-05 23.6 1.2 6.5e-05 22.8 0.8 1.5 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 EPR79583.1 - 3.9e-05 23.8 0.2 6.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPR79583.1 - 3.9e-05 23.4 1.4 6e-05 22.8 1.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EPR79583.1 - 8.2e-05 22.5 1.0 8.2e-05 22.5 0.7 1.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EPR79583.1 - 8.2e-05 22.6 0.7 0.00027 20.9 0.4 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EPR79583.1 - 0.0002 20.5 0.0 0.00034 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KTI12 PF08433.5 EPR79583.1 - 0.00042 19.6 0.9 0.0015 17.7 0.6 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 EPR79583.1 - 0.00043 20.2 2.5 0.0018 18.1 1.8 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.1 EPR79583.1 - 0.00079 19.3 0.0 0.0024 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EPR79583.1 - 0.00099 19.0 0.4 0.012 15.4 0.0 2.1 1 1 1 2 2 2 1 Adenylate kinase AAA_3 PF07726.6 EPR79583.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPR79583.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF386 PF04074.7 EPR79583.1 - 0.0024 17.3 1.8 0.0046 16.4 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF386) NACHT PF05729.7 EPR79583.1 - 0.0027 17.4 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 EPR79583.1 - 0.0034 16.9 3.1 0.0045 16.5 0.2 2.2 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EPR79583.1 - 0.0041 15.8 0.2 0.0069 15.1 0.1 1.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 EPR79583.1 - 0.0042 16.1 0.0 0.0063 15.5 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain DUF258 PF03193.11 EPR79583.1 - 0.0048 16.0 0.1 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPR79583.1 - 0.0051 16.7 0.1 0.0094 15.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EPR79583.1 - 0.0056 16.2 0.1 0.0085 15.6 0.1 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.4 EPR79583.1 - 0.0068 15.8 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EPR79583.1 - 0.0074 15.7 0.4 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EPR79583.1 - 0.0082 15.2 0.0 0.066 12.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EPR79583.1 - 0.01 15.2 0.7 0.021 14.2 0.5 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EPR79583.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EPR79583.1 - 0.012 14.6 0.4 0.019 13.9 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EPR79583.1 - 0.013 15.3 0.9 0.016 15.0 0.6 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EPR79583.1 - 0.014 14.2 0.1 0.026 13.3 0.1 1.8 1 1 0 1 1 1 0 NB-ARC domain Miro PF08477.8 EPR79583.1 - 0.016 15.7 1.1 0.033 14.6 0.2 1.9 1 1 1 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EPR79583.1 - 0.02 14.4 4.9 0.02 14.4 1.6 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EPR79583.1 - 0.022 14.4 1.3 0.025 14.2 0.1 1.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EPR79583.1 - 0.022 13.4 0.1 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.22 EPR79583.1 - 0.027 14.7 0.8 0.04 14.2 0.5 1.5 1 1 0 1 1 1 0 ABC transporter AAA_2 PF07724.9 EPR79583.1 - 0.045 13.6 0.0 0.076 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) T2SE PF00437.15 EPR79583.1 - 0.05 12.5 0.1 0.05 12.5 0.1 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EPR79583.1 - 0.057 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EPR79583.1 - 0.061 12.1 0.2 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 ArgK protein Mg_chelatase PF01078.16 EPR79583.1 - 0.075 12.1 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PTS_IIB PF02302.12 EPR79583.1 - 0.075 13.5 0.3 2.7 8.5 0.0 2.5 1 1 2 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit UPF0079 PF02367.12 EPR79583.1 - 0.084 12.5 1.9 0.089 12.4 0.1 2.0 2 1 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 EPR79583.1 - 0.085 11.7 0.1 0.4 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EPR79583.1 - 0.13 11.7 0.0 0.14 11.5 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.12 EPR79583.1 - 0.22 10.8 3.6 0.29 10.4 0.1 2.3 1 1 2 3 3 3 0 Thymidylate kinase DUF87 PF01935.12 EPR79583.1 - 0.23 11.2 2.1 0.29 10.9 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 EPR79583.1 - 0.26 10.7 2.1 0.45 9.9 1.4 1.9 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EPR79583.1 - 0.28 10.6 1.2 0.45 9.9 0.2 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EPR79583.1 - 0.41 9.7 4.4 0.44 9.6 1.7 2.1 1 1 1 2 2 2 0 KaiC SNARE PF05739.14 EPR79584.1 - 0.077 12.6 0.3 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 SNARE domain MS_channel PF00924.13 EPR79584.1 - 0.13 11.5 9.1 0.076 12.3 1.7 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel Peptidase_S28 PF05577.7 EPR79584.1 - 0.13 10.7 1.9 0.18 10.3 1.3 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PuR_N PF09182.5 EPR79584.1 - 0.16 11.5 4.5 0.47 10.1 0.4 2.7 2 1 0 2 2 2 0 Bacterial purine repressor, N-terminal DUF2216 PF10226.4 EPR79584.1 - 0.22 10.9 2.3 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DASH_Dad4 PF08650.5 EPR79584.1 - 0.26 11.2 4.7 1.9 8.4 1.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF948 PF06103.6 EPR79584.1 - 0.45 10.4 4.3 0.37 10.6 1.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Kinesin-relat_1 PF12711.2 EPR79584.1 - 0.52 10.7 4.0 0.78 10.1 0.7 2.4 2 0 0 2 2 2 0 Kinesin motor MotA_activ PF09114.5 EPR79584.1 - 1.3 8.7 6.9 0.22 11.3 0.8 2.4 2 1 0 2 2 2 0 Transcription factor MotA, activation domain Sel1 PF08238.7 EPR79585.1 - 2.1e-114 371.4 37.9 8e-11 42.2 0.2 16.0 15 1 0 15 15 15 14 Sel1 repeat TPR_11 PF13414.1 EPR79585.1 - 4.7e-12 45.3 35.8 0.029 13.9 0.0 8.4 3 2 6 9 9 9 8 TPR repeat TPR_6 PF13174.1 EPR79585.1 - 7.1e-06 26.1 14.9 37 5.0 0.0 9.5 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPR79585.1 - 0.0084 16.2 27.5 9.7 6.6 0.2 10.5 7 3 3 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPR79585.1 - 0.021 14.7 20.5 0.68 9.9 0.2 7.8 2 2 7 9 9 9 0 Tetratricopeptide repeat MIT PF04212.13 EPR79585.1 - 0.034 14.0 17.7 36 4.3 0.0 8.0 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain RNA_pol_A_bac PF01000.21 EPR79586.1 - 1.9e-21 76.2 2.3 6.7e-21 74.5 1.2 2.1 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPR79586.1 - 2.6e-10 39.2 0.1 3.9e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DASH_Duo1 PF08651.5 EPR79587.1 - 2.4 7.7 9.9 0.73 9.4 3.6 2.6 2 1 0 2 2 2 0 DASH complex subunit Duo1 NPL4 PF05021.10 EPR79588.1 - 7e-37 127.2 7.4 9.9e-36 123.4 5.1 2.1 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EPR79588.1 - 8.4e-20 70.9 16.2 1.2e-19 70.4 6.4 3.8 2 1 0 2 2 2 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.13 EPR79588.1 - 0.002 17.2 2.2 0.002 17.2 1.5 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others BHD_1 PF10403.4 EPR79588.1 - 0.0055 16.1 0.1 3.4 7.2 0.0 2.7 2 0 0 2 2 2 2 Rad4 beta-hairpin domain 1 UN_NPL4 PF11543.3 EPR79588.1 - 0.029 14.6 1.0 0.29 11.4 0.0 3.0 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 AAA_11 PF13086.1 EPR79589.1 - 1e-20 74.3 7.2 2.7e-14 53.3 0.0 3.9 3 1 1 4 4 4 2 AAA domain AAA_12 PF13087.1 EPR79589.1 - 2.4e-12 46.6 4.2 1.2e-11 44.3 0.4 4.6 4 1 1 5 5 5 2 AAA domain Viral_helicase1 PF01443.13 EPR79589.1 - 1.2e-11 44.5 5.6 4.1e-08 33.0 3.9 3.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EPR79589.1 - 2.6e-06 27.1 0.0 6.2e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EPR79589.1 - 5.5e-06 26.4 0.0 3e-05 24.1 0.0 2.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPR79589.1 - 0.00041 20.0 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 EPR79589.1 - 0.00071 19.2 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EPR79589.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain dUTPase PF00692.14 EPR79590.1 - 5e-20 71.2 0.0 5.7e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase RRM_1 PF00076.17 EPR79591.1 - 1e-16 60.2 6.2 8e-12 44.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR79591.1 - 4.6e-16 58.5 2.4 1.2e-12 47.6 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79591.1 - 2.9e-07 30.2 6.3 6.9e-05 22.6 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KdpD PF02702.12 EPR79591.1 - 0.014 14.4 1.9 0.029 13.5 1.3 1.4 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain DUF912 PF06024.7 EPR79592.1 - 0.023 14.7 1.0 0.023 14.7 0.7 7.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 EPR79592.1 - 0.041 14.0 1.3 0.041 14.0 0.9 8.8 2 2 1 3 3 3 0 Domain of unknown function (DUF3899) DUF3753 PF12575.3 EPR79592.1 - 0.046 13.5 0.7 0.046 13.5 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) Gemini_mov PF01708.11 EPR79592.1 - 0.31 10.6 1.4 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein YpM PF09144.5 EPR79593.1 - 0.0063 16.4 0.2 0.0063 16.4 0.1 2.1 2 1 1 3 3 3 1 Yersinia pseudotuberculosis mitogen DUF912 PF06024.7 EPR79593.1 - 0.26 11.3 2.0 0.72 9.9 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2062 PF09835.4 EPR79594.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Chromadorea_ALT PF05535.7 EPR79595.1 - 0.01 15.9 11.9 0.21 11.6 2.0 2.5 1 1 0 2 2 2 0 Chromadorea ALT protein GRASP55_65 PF04495.9 EPR79596.1 - 7.6e-21 74.5 0.3 8.8e-17 61.3 0.0 2.5 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain MCM PF00493.18 EPR79597.1 - 1.4e-131 438.1 1.0 2.4e-131 437.4 0.7 1.3 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EPR79597.1 - 7.4e-13 48.1 0.1 1.6e-07 30.7 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 EPR79597.1 - 6.3e-12 46.0 5.2 6.3e-12 46.0 3.6 2.7 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EPR79597.1 - 7.5e-10 38.6 0.1 4.2e-09 36.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPR79597.1 - 1.5e-06 27.8 0.0 5.2e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPR79597.1 - 0.00034 20.1 0.1 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF998 PF06197.8 EPR79598.1 - 0.027 13.7 5.5 0.037 13.3 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) ABC2_membrane_2 PF12679.2 EPR79598.1 - 0.34 9.7 6.6 0.43 9.3 4.5 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2232 PF09991.4 EPR79598.1 - 0.53 9.2 12.0 0.74 8.7 8.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PHD PF00628.24 EPR79600.1 - 1.3e-09 37.6 10.6 2e-09 36.9 7.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPR79600.1 - 0.0017 17.5 4.7 0.003 16.8 3.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EPR79600.1 - 0.0056 16.6 1.2 0.011 15.7 0.9 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPR79600.1 - 0.0066 16.5 5.4 0.015 15.4 3.8 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain CagZ PF09053.5 EPR79600.1 - 0.015 14.6 4.2 0.018 14.3 2.7 1.3 1 1 0 1 1 1 0 CagZ EAP30 PF04157.11 EPR79600.1 - 0.024 13.8 1.2 0.027 13.6 0.5 1.4 1 1 0 1 1 1 0 EAP30/Vps36 family ORF11CD3 PF10549.4 EPR79600.1 - 0.064 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 ORF11CD3 domain Sp100 PF03172.8 EPR79600.1 - 0.079 12.9 1.1 0.12 12.3 0.3 1.6 2 0 0 2 2 2 0 Sp100 domain DASH_Dam1 PF08653.5 EPR79600.1 - 0.39 10.4 3.6 6 6.7 0.2 3.5 3 1 1 4 4 4 0 DASH complex subunit Dam1 DUF1319 PF07028.6 EPR79600.1 - 0.49 10.5 5.1 1.7 8.8 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) zf-RING-like PF08746.6 EPR79600.1 - 1.5 8.8 8.0 3.2 7.8 5.6 1.6 1 0 0 1 1 1 0 RING-like domain DUF948 PF06103.6 EPR79600.1 - 2.9 7.8 6.0 4.1 7.3 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Orthopox_F14 PF06076.7 EPR79600.1 - 7.1 6.7 8.3 1.3 9.1 2.9 1.9 2 0 0 2 2 2 0 Orthopoxvirus F14 protein Noc2 PF03715.8 EPR79601.1 - 4.6e-11 42.1 8.0 4.6e-11 42.1 5.5 1.6 1 1 0 1 1 1 1 Noc2p family Far-17a_AIG1 PF04750.9 EPR79602.1 - 3.1e-22 78.7 13.3 4.4e-22 78.2 9.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein EII-Sor PF03609.9 EPR79602.1 - 0.017 14.3 0.5 0.017 14.3 0.3 2.0 2 0 0 2 2 2 0 PTS system sorbose-specific iic component PAH PF02671.16 EPR79603.1 - 1.1e-28 98.5 8.1 5.2e-12 45.1 0.0 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPR79603.1 - 7.4e-17 60.9 1.4 4.3e-16 58.5 1.0 2.4 1 0 0 1 1 1 1 Sin3 family co-repressor IncA PF04156.9 EPR79603.1 - 0.076 12.5 5.5 2 7.9 1.0 2.9 2 0 0 2 2 2 0 IncA protein Lactamase_B_2 PF12706.2 EPR79604.1 - 6.9e-32 110.5 1.5 1.4e-31 109.5 1.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPR79604.1 - 2.9e-09 36.8 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EPR79604.1 - 2.6e-06 26.7 0.6 1.4e-05 24.4 0.2 2.4 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_3 PF13483.1 EPR79604.1 - 0.017 14.8 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF155 PF02582.9 EPR79605.1 - 1.1e-49 168.6 1.8 1.6e-49 168.2 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CorA PF01544.13 EPR79605.1 - 0.0018 17.4 4.8 0.0029 16.7 3.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sp100 PF03172.8 EPR79605.1 - 0.0061 16.5 1.8 0.027 14.4 0.4 2.2 1 1 1 2 2 2 1 Sp100 domain tRNA_NucTran2_2 PF13735.1 EPR79606.1 - 0.039 13.7 0.2 0.077 12.8 0.1 1.5 1 1 1 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Med11 PF10280.4 EPR79606.1 - 0.17 11.9 2.7 0.7 9.9 0.2 2.7 2 1 1 3 3 3 0 Mediator complex protein HTH_17 PF12728.2 EPR79607.1 - 0.097 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2697 PF10906.3 EPR79608.1 - 0.012 15.6 0.0 0.071 13.1 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) DUF2346 PF09803.4 EPR79608.1 - 0.1 12.4 0.3 0.1 12.4 0.2 5.2 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2346) Peptidase_M48 PF01435.13 EPR79609.1 - 8.9e-41 139.9 0.0 1.4e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EPR79609.1 - 0.0025 16.8 0.2 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EPR79609.1 - 0.15 11.4 2.4 4.7 6.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DSBA PF01323.15 EPR79610.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Menin PF05053.8 EPR79610.1 - 1.7 6.6 9.6 2.2 6.3 6.6 1.1 1 0 0 1 1 1 0 Menin Mucin PF01456.12 EPR79610.1 - 3.1 7.5 10.9 4.8 6.9 7.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PTH2 PF01981.11 EPR79611.1 - 0.0005 19.7 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 NodS PF05401.6 EPR79611.1 - 0.07 12.5 0.1 0.072 12.4 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PLDc_2 PF13091.1 EPR79613.1 - 1.9e-15 56.7 13.3 1.5e-09 37.6 0.6 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EPR79613.1 - 6.5e-08 32.1 1.2 1.7e-06 27.6 0.1 2.5 2 0 0 2 2 2 1 Phospholipase D Active site motif KH_1 PF00013.24 EPR79614.1 - 0.00073 19.1 0.4 0.0015 18.1 0.3 1.5 1 0 0 1 1 1 1 KH domain THF_DHG_CYH_C PF02882.14 EPR79614.1 - 0.0043 16.1 0.3 0.0071 15.4 0.2 1.4 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2764 PF10962.3 EPR79614.1 - 0.0077 15.4 0.5 0.011 14.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2764) DUF4646 PF15496.1 EPR79614.1 - 0.089 12.8 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) HECT PF00632.20 EPR79615.1 - 1e-75 254.8 9.4 2.2e-75 253.7 6.5 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2862 PF11061.3 EPR79616.1 - 0.11 12.1 0.8 0.33 10.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2862) Thioredoxin PF00085.15 EPR79617.1 - 2.4e-15 56.0 0.1 2.8e-15 55.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPR79617.1 - 5.5e-09 36.2 0.1 8e-08 32.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPR79617.1 - 2e-07 31.0 0.6 0.0024 17.9 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EPR79617.1 - 3.4e-06 26.7 0.1 9.3e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 EPR79617.1 - 8.1e-05 22.3 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EPR79617.1 - 0.00014 21.4 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.5 EPR79617.1 - 0.00025 20.6 0.1 0.086 12.3 0.0 2.0 1 1 1 2 2 2 2 Redoxin DUF836 PF05768.9 EPR79617.1 - 0.0022 18.2 0.1 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.1 EPR79617.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EPR79617.1 - 0.004 17.1 0.1 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin UQ_con PF00179.21 EPR79618.1 - 2.9e-34 117.5 1.9 3.3e-34 117.3 1.3 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPR79618.1 - 0.033 14.0 1.1 0.06 13.2 0.8 1.7 1 1 0 1 1 1 0 RWD domain PCI PF01399.22 EPR79619.1 - 1.1e-12 48.1 2.0 1.1e-12 48.1 1.4 2.8 3 1 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPR79619.1 - 3.3e-05 23.7 4.5 3.5e-05 23.6 0.8 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 HTH_10 PF04967.7 EPR79619.1 - 0.11 12.1 0.5 0.5 9.9 0.0 2.4 2 0 0 2 2 2 0 HTH DNA binding domain YmgB PF10798.3 EPR79619.1 - 0.36 10.6 3.3 5.7 6.8 0.2 2.6 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR TRM PF02005.11 EPR79620.1 - 3.2e-88 296.2 1.4 7.9e-88 294.9 1.0 1.5 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EPR79620.1 - 6.9e-05 22.2 0.0 0.00028 20.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 EPR79620.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EPR79620.1 - 0.017 14.7 7.2 0.0097 15.5 3.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EPR79620.1 - 0.37 11.2 3.6 0.46 10.9 0.1 2.6 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_2 PF00152.15 EPR79621.1 - 3e-68 230.0 0.2 4.4e-68 229.5 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPR79621.1 - 2.3e-08 33.7 0.2 4.3e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PAP2 PF01569.16 EPR79622.1 - 1.6e-08 34.3 5.5 5.3e-08 32.6 3.7 2.0 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EPR79622.1 - 1.4 9.2 9.9 14 6.0 5.0 2.6 1 1 1 2 2 2 0 PAP2 superfamily C-terminal DSHCT PF08148.7 EPR79623.1 - 1.8e-35 121.8 0.5 4.3e-35 120.5 0.1 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EPR79623.1 - 4e-20 71.9 0.1 9.7e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79623.1 - 2.3e-06 27.3 0.0 6.4e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SmpA_OmlA PF04355.8 EPR79624.1 - 0.24 11.0 3.5 8.2 6.1 0.1 2.4 2 0 0 2 2 2 0 SmpA / OmlA family LRR_8 PF13855.1 EPR79625.1 - 2.6e-34 116.7 49.7 1.9e-07 30.7 3.9 7.3 5 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EPR79625.1 - 4.4e-28 96.4 62.0 3.3e-08 32.9 0.3 9.3 5 2 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79625.1 - 4e-18 62.6 52.8 0.002 17.9 0.1 14.9 13 1 0 13 13 13 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR79625.1 - 5.6e-09 34.7 34.8 0.13 12.5 0.0 13.4 14 0 0 14 14 14 4 Leucine rich repeat B5 PF03484.10 EPR79628.1 - 1.8e-19 69.3 6.2 2e-13 49.9 0.8 3.3 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.12 EPR79628.1 - 2.3e-15 56.4 0.1 4.9e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain DUF334 PF03904.8 EPR79628.1 - 0.25 10.6 7.8 0.98 8.6 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF334) LRR_8 PF13855.1 EPR79629.1 - 2e-20 72.3 63.6 1.1e-07 31.4 6.8 7.8 4 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EPR79629.1 - 1.1e-18 66.3 78.0 1.4e-06 27.7 6.2 10.3 6 3 7 13 13 13 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79629.1 - 7e-15 52.7 61.5 0.044 13.8 0.3 14.7 12 2 1 13 13 13 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR79629.1 - 3.2e-09 35.4 43.3 0.14 12.4 0.1 12.6 12 0 0 12 12 12 4 Leucine rich repeat LRR_6 PF13516.1 EPR79629.1 - 2.6e-05 23.8 55.3 2.2 8.6 0.3 13.2 12 1 1 13 13 13 5 Leucine Rich repeat Pkinase PF00069.20 EPR79630.1 - 1.1e-10 41.0 0.0 1.3e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EPR79630.1 - 0.00084 18.3 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 EPR79630.1 - 0.032 13.3 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4367 PF14285.1 EPR79631.1 - 0.56 9.5 9.4 0.27 10.5 4.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Methylase_S PF01420.14 EPR79631.1 - 0.58 10.1 10.6 0.67 9.9 7.3 1.1 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain vATP-synt_AC39 PF01992.11 EPR79632.1 - 3.3e-09 36.3 7.0 1e-07 31.3 4.8 2.1 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit Osmo_MPGsynth PF09488.5 EPR79632.1 - 0.014 14.1 0.7 0.031 12.9 0.4 1.3 1 1 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) vATP-synt_AC39 PF01992.11 EPR79633.1 - 8.2e-10 38.3 0.1 1e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit GNVR PF13807.1 EPR79633.1 - 1e-06 28.3 0.4 2.2e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase LRR_4 PF12799.2 EPR79634.1 - 2e-33 113.4 96.8 1.5e-06 27.6 3.4 9.9 5 4 6 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79634.1 - 2.5e-30 103.9 72.6 3.5e-08 33.0 4.2 8.1 5 2 4 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 EPR79634.1 - 2.8e-14 50.9 82.9 0.0016 18.2 0.5 14.9 13 4 1 14 14 14 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR79634.1 - 5.5e-07 28.7 65.5 0.84 10.1 0.3 14.4 15 0 0 15 15 15 5 Leucine rich repeat LRR_6 PF13516.1 EPR79634.1 - 0.051 13.6 1.0 0.051 13.6 0.7 13.6 11 2 2 13 13 13 0 Leucine Rich repeat YcxB PF14317.1 EPR79634.1 - 0.29 10.3 5.5 21 4.4 0.1 4.1 3 2 1 4 4 4 0 YcxB-like protein Pkinase PF00069.20 EPR79635.1 - 9.1e-08 31.5 0.0 9.1e-08 31.5 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain DUF2382 PF09557.5 EPR79635.1 - 2.6 8.0 5.8 2.3 8.1 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF2382) YjeF_N PF03853.10 EPR79636.1 - 7.8e-30 103.6 0.0 9.8e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus CAF1A PF12253.3 EPR79637.1 - 5.8e-08 32.7 3.5 1.6e-07 31.3 2.4 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A NABP PF07990.7 EPR79637.1 - 1.9 7.6 5.1 2.7 7.1 3.5 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP ASCH PF04266.9 EPR79638.1 - 0.048 14.0 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 ASCH domain LRR_4 PF12799.2 EPR79638.1 - 0.6 9.7 12.4 3.7 7.2 0.1 5.4 4 3 2 6 6 6 0 Leucine Rich repeats (2 copies) DEAD PF00270.24 EPR79639.1 - 8.6e-37 126.2 0.1 8.6e-37 126.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79639.1 - 1.1e-15 57.2 0.1 6.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79639.1 - 1.3e-08 34.9 1.1 1.3e-08 34.9 0.7 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4217 PF13959.1 EPR79639.1 - 3.1e-07 29.8 0.1 8.6e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C_2 PF13307.1 EPR79639.1 - 0.006 16.5 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain SecA_DEAD PF07517.9 EPR79639.1 - 0.015 14.6 0.4 0.03 13.5 0.0 1.9 2 1 0 2 2 2 0 SecA DEAD-like domain PhoH PF02562.11 EPR79639.1 - 0.038 13.2 0.1 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein UPF0113 PF03657.8 EPR79640.1 - 4.5e-05 23.1 0.4 0.0001 21.9 0.3 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EPR79640.1 - 0.00062 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 PUA domain DEAD PF00270.24 EPR79641.1 - 2e-12 46.9 0.0 5.2e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79641.1 - 1.6e-11 43.8 0.1 7.6e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 EPR79641.1 - 3.5e-09 36.5 0.0 1.5e-08 34.6 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Zot PF05707.7 EPR79641.1 - 0.00013 21.5 0.1 0.00043 19.8 0.0 1.9 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Flavi_DEAD PF07652.9 EPR79641.1 - 0.00022 21.0 0.0 0.00058 19.6 0.0 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_22 PF13401.1 EPR79641.1 - 0.00068 19.7 2.4 0.0011 19.1 0.4 2.3 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EPR79641.1 - 0.0042 16.0 0.0 0.0092 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EPR79641.1 - 0.21 11.1 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 EPR79641.1 - 1.3 8.9 9.5 2 8.3 2.4 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Myc_target_1 PF15179.1 EPR79642.1 - 0.0011 18.6 0.5 0.0018 17.8 0.3 1.5 1 1 0 1 1 1 1 Myc target protein 1 DUF2371 PF10177.4 EPR79642.1 - 0.019 14.8 0.6 0.044 13.6 0.0 2.0 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2500 PF10694.4 EPR79642.1 - 0.054 13.4 0.2 0.16 11.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) Neurensin PF14927.1 EPR79642.1 - 0.064 12.6 0.0 5.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Neurensin ODV-E18 PF10717.4 EPR79642.1 - 0.08 12.3 1.6 0.085 12.3 0.2 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Folate_carrier PF01770.13 EPR79642.1 - 0.08 11.4 1.6 0.059 11.8 0.3 1.4 1 1 0 1 1 1 0 Reduced folate carrier DUF1049 PF06305.6 EPR79642.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1043 PF06295.7 EPR79642.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Tetraspannin PF00335.15 EPR79642.1 - 1.1 8.4 5.0 3.9 6.6 3.4 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF1510 PF07423.6 EPR79642.1 - 1.3 8.3 16.9 7.6 5.8 11.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) YjgP_YjgQ PF03739.9 EPR79642.1 - 2 7.0 4.0 2.8 6.5 2.8 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Ly49 PF08391.5 EPR79642.1 - 4 7.5 13.5 0.28 11.3 3.6 2.5 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region ATP-synt_ab PF00006.20 EPR79643.1 - 3.3e-61 206.5 0.0 4.3e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPR79643.1 - 6.1e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPR79643.1 - 2.9e-11 43.3 1.6 5.6e-11 42.4 1.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPR79643.1 - 0.0014 18.5 0.9 0.0031 17.3 0.6 1.6 1 0 0 1 1 1 1 HAS barrel domain Proteasome PF00227.21 EPR79644.1 - 1e-45 155.4 2.6 1.2e-45 155.1 1.8 1.1 1 0 0 1 1 1 1 Proteasome subunit ATP-synt_ab PF00006.20 EPR79645.1 - 1.3e-112 374.5 0.0 2.2e-112 373.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPR79645.1 - 3.9e-20 72.4 0.2 8e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPR79645.1 - 7.8e-14 51.6 5.0 9.2e-14 51.4 1.7 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EPR79645.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain dUTPase PF00692.14 EPR79646.1 - 3.9e-20 71.6 0.0 4.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase Peptidase_S26 PF10502.4 EPR79646.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 GCD14 PF08704.5 EPR79647.1 - 5.1e-22 78.5 0.0 8.9e-21 74.5 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EPR79647.1 - 8.7e-07 28.6 4.9 1.1e-05 25.0 3.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EPR79647.1 - 4.1e-06 26.0 0.2 1.5e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EPR79647.1 - 4.4e-06 26.3 0.0 2.7e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPR79647.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPR79647.1 - 0.0098 15.5 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPR79647.1 - 0.064 12.3 1.1 0.094 11.8 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) T2SE PF00437.15 EPR79647.1 - 0.066 12.1 0.1 0.095 11.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Xpo1 PF08389.7 EPR79648.1 - 1.4e-24 86.6 6.4 1.4e-24 86.6 4.4 5.0 5 1 1 6 6 6 1 Exportin 1-like protein CRM1_C PF08767.6 EPR79648.1 - 1.3e-18 66.9 25.5 1.3e-18 66.9 17.7 3.8 3 2 1 4 4 4 1 CRM1 C terminal RST PF12174.3 EPR79650.1 - 1.7 8.4 4.5 1.1 9.1 1.2 2.0 1 1 1 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain DUF4514 PF14986.1 EPR79651.1 - 0.19 11.5 1.6 0.31 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Neur_chan_memb PF02932.11 EPR79652.1 - 6.8 6.5 11.3 0.068 13.0 0.6 2.6 4 0 0 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin PF00085.15 EPR79653.1 - 6.8e-07 28.9 0.0 1.6e-06 27.6 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin Phosducin PF02114.11 EPR79653.1 - 1.2e-05 24.2 0.7 2.2e-05 23.3 0.5 1.5 1 1 0 1 1 1 1 Phosducin DUF1803 PF08820.5 EPR79653.1 - 0.059 13.0 1.2 0.1 12.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) DUF643 PF04867.7 EPR79653.1 - 0.59 10.5 5.3 0.64 10.4 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF643) RRM_1 PF00076.17 EPR79654.1 - 1.7e-33 114.0 13.5 4.7e-18 64.5 0.4 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR79654.1 - 4.6e-22 77.7 7.1 5e-12 45.6 0.2 3.3 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79654.1 - 9.9e-19 66.9 13.0 3.2e-09 36.4 0.1 4.9 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPR79654.1 - 1.2e-07 31.4 0.2 0.0015 18.2 0.0 3.5 3 1 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EPR79654.1 - 7.7e-06 25.7 3.2 0.015 15.1 0.4 2.9 3 0 0 3 3 3 2 RNA binding motif Histidinol_dh PF00815.15 EPR79655.1 - 0.056 12.0 0.2 0.085 11.4 0.2 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase Actin PF00022.14 EPR79656.1 - 8e-152 505.2 0.0 9.4e-152 504.9 0.0 1.0 1 0 0 1 1 1 1 Actin Homeobox PF00046.24 EPR79657.1 - 3.2e-12 45.8 3.5 5.5e-12 45.1 2.4 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPR79657.1 - 0.0064 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Spore_III_AF PF09581.5 EPR79657.1 - 0.054 13.3 1.2 0.079 12.8 0.9 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ribosomal_L18_c PF14204.1 EPR79657.1 - 0.082 13.4 4.3 0.19 12.3 2.9 1.6 1 1 0 1 1 1 0 Ribosomal L18 C-terminal region HTH_17 PF12728.2 EPR79657.1 - 0.13 12.5 0.3 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain UCH PF00443.24 EPR79658.1 - 5.2e-05 22.4 4.2 0.0041 16.2 2.1 2.1 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Fig1 PF12351.3 EPR79659.1 - 0.076 12.8 0.2 0.083 12.7 0.1 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 TP_methylase PF00590.15 EPR79660.1 - 2.1e-16 60.2 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases AAA_2 PF07724.9 EPR79661.1 - 5.5e-38 130.5 1.5 1.2e-36 126.2 0.6 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPR79661.1 - 2.6e-22 79.4 2.4 1e-11 45.1 0.0 3.5 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EPR79661.1 - 2.1e-16 59.5 2.1 7.4e-16 57.8 0.1 3.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EPR79661.1 - 8.3e-16 57.9 0.3 2e-11 43.7 0.1 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPR79661.1 - 6.2e-11 42.6 0.0 0.00074 19.5 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EPR79661.1 - 9.9e-10 39.2 5.4 7.8e-06 26.7 0.1 4.2 4 2 0 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EPR79661.1 - 1.6e-08 34.1 0.1 3.8e-06 26.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPR79661.1 - 1e-07 31.5 0.0 0.00013 21.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EPR79661.1 - 1.7e-07 31.2 1.1 0.013 15.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EPR79661.1 - 2.7e-06 27.0 0.0 0.041 13.6 0.0 2.8 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EPR79661.1 - 3e-06 26.5 0.2 0.27 10.3 0.2 3.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EPR79661.1 - 4.6e-06 26.7 5.2 0.017 15.2 0.3 4.7 3 2 0 3 3 3 2 AAA domain Clp_N PF02861.15 EPR79661.1 - 3.4e-05 23.6 0.0 0.051 13.5 0.0 2.8 2 0 0 2 2 2 1 Clp amino terminal domain Zeta_toxin PF06414.7 EPR79661.1 - 3.8e-05 22.8 0.0 0.0084 15.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EPR79661.1 - 4e-05 23.7 0.1 1.1 9.5 0.0 3.7 4 0 0 4 4 3 2 RNA helicase AAA_18 PF13238.1 EPR79661.1 - 0.00012 22.3 13.4 0.2 11.9 3.0 4.8 3 1 0 3 3 3 2 AAA domain Torsin PF06309.6 EPR79661.1 - 0.00013 21.8 0.0 0.0022 17.8 0.0 3.0 3 0 0 3 3 2 1 Torsin ResIII PF04851.10 EPR79661.1 - 0.00013 21.8 1.1 0.029 14.1 0.0 3.9 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EPR79661.1 - 0.00018 21.4 0.0 0.66 9.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EPR79661.1 - 0.00022 20.2 0.2 0.013 14.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein RuvB_N PF05496.7 EPR79661.1 - 0.00024 20.2 0.8 0.25 10.3 0.0 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 EPR79661.1 - 0.00031 20.2 0.2 0.074 12.4 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain NACHT PF05729.7 EPR79661.1 - 0.00033 20.3 0.0 0.97 9.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EPR79661.1 - 0.00076 19.4 0.8 0.029 14.3 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_3 PF07726.6 EPR79661.1 - 0.00081 18.9 0.3 0.11 12.1 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPR79661.1 - 0.00093 18.6 0.0 0.9 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPR79661.1 - 0.0018 17.7 0.2 1 8.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EPR79661.1 - 0.0026 16.9 0.0 0.11 11.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 EPR79661.1 - 0.0029 16.2 0.0 0.052 12.1 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.18 EPR79661.1 - 0.0055 16.1 1.3 0.26 10.6 0.0 3.5 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EPR79661.1 - 0.0057 16.1 0.0 3.2 7.1 0.0 3.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EPR79661.1 - 0.0061 16.8 6.0 0.72 10.1 0.0 4.0 4 0 0 4 4 4 1 ABC transporter FtsK_SpoIIIE PF01580.13 EPR79661.1 - 0.0082 15.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EPR79661.1 - 0.012 15.5 0.0 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EPR79661.1 - 0.013 14.7 2.8 0.043 13.0 0.0 2.9 2 1 0 3 3 2 0 PhoH-like protein AAA_30 PF13604.1 EPR79661.1 - 0.014 14.9 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPR79661.1 - 0.017 14.7 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EPR79661.1 - 0.036 13.7 0.0 2.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 EPR79661.1 - 0.041 13.3 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase IncA PF04156.9 EPR79661.1 - 0.061 12.9 11.2 0.018 14.6 4.7 2.3 2 0 0 2 2 2 0 IncA protein Band_7 PF01145.20 EPR79661.1 - 0.25 11.2 3.9 0.7 9.7 0.6 2.9 2 1 0 2 2 2 0 SPFH domain / Band 7 family AAA_23 PF13476.1 EPR79661.1 - 0.66 10.2 39.0 0.025 14.9 7.0 3.8 2 2 1 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.4 EPR79661.1 - 6.6 6.5 17.6 1.1 9.1 8.6 2.4 2 1 1 3 3 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rotavirus_VP7 PF05868.6 EPR79662.1 - 0.011 14.8 0.1 0.024 13.7 0.1 1.4 1 1 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Pep3_Vps18 PF05131.9 EPR79663.1 - 0.22 10.9 4.4 0.19 11.1 0.2 2.6 3 0 0 3 3 3 0 Pep3/Vps18/deep orange family CPSF_A PF03178.10 EPR79664.1 - 3.6e-37 128.1 1.9 7.5e-37 127.1 1.3 1.5 1 0 0 1 1 1 1 CPSF A subunit region AIF_C PF14721.1 EPR79664.1 - 9.4 6.4 11.7 0.94 9.7 3.6 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Proteasome PF00227.21 EPR79665.1 - 1.8e-22 79.5 0.0 2.3e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPR79665.1 - 4.6e-12 45.0 0.0 8.3e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ubiquitin PF00240.18 EPR79666.1 - 1.9e-34 116.8 0.7 3.2e-34 116.1 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPR79666.1 - 1.4e-19 69.5 0.6 2.6e-19 68.6 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 EPR79666.1 - 1.8e-08 34.0 1.2 3.6e-08 33.1 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 EPR79666.1 - 3.3e-05 24.0 0.1 0.00013 22.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPR79666.1 - 3.3e-05 23.6 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPR79666.1 - 0.00029 20.7 0.7 0.00055 19.7 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPR79666.1 - 0.012 15.7 0.8 0.017 15.2 0.5 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2207 PF09972.4 EPR79666.1 - 0.045 12.3 0.7 0.049 12.2 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 EPR79666.1 - 0.064 11.5 2.0 0.55 8.4 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 EPR79666.1 - 0.068 13.2 0.3 0.14 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) HAD_2 PF13419.1 EPR79668.1 - 2.6e-08 34.2 0.0 2.4e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPR79668.1 - 0.022 14.3 2.5 1.3 8.6 0.1 2.9 3 0 0 3 3 3 0 Acid Phosphatase HAD PF12710.2 EPR79668.1 - 0.03 14.5 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_11 PF13086.1 EPR79669.1 - 1.3e-53 182.0 0.4 1.3e-53 182.0 0.3 4.0 3 2 0 3 3 2 1 AAA domain AAA_12 PF13087.1 EPR79669.1 - 1.9e-47 161.2 2.4 1.9e-47 161.2 1.7 3.4 4 2 1 5 5 5 1 AAA domain AAA_19 PF13245.1 EPR79669.1 - 4.7e-12 45.4 0.0 9.7e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain UPF1_Zn_bind PF09416.5 EPR79669.1 - 6.3e-06 25.8 11.3 6.3e-06 25.8 7.8 2.4 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.1 EPR79669.1 - 8.7e-06 25.4 0.0 6e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EPR79669.1 - 1.3e-05 25.1 1.1 1.3e-05 25.1 0.7 4.4 6 0 0 6 6 6 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPR79669.1 - 2.9e-05 23.6 0.0 7.7e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EPR79669.1 - 0.00025 19.9 0.1 0.00062 18.6 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EPR79669.1 - 0.0034 17.5 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPR79669.1 - 0.23 10.8 0.0 0.51 9.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPR79669.1 - 0.29 11.9 7.9 2.7 8.8 0.4 3.5 3 1 0 3 3 2 0 AAA domain RicinB_lectin_2 PF14200.1 EPR79670.1 - 2.5e-06 27.7 0.1 0.0017 18.6 0.0 1.9 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EPR79670.1 - 0.00016 21.7 0.2 0.00034 20.6 0.1 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF3373 PF11853.3 EPR79670.1 - 0.002 16.7 0.5 0.0029 16.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) DUF342 PF03961.8 EPR79670.1 - 0.0023 16.4 3.6 0.0028 16.1 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 EPR79670.1 - 0.0064 15.9 3.2 0.0099 15.3 2.2 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Taxilin PF09728.4 EPR79670.1 - 0.0099 14.9 5.5 0.015 14.4 3.8 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4355 PF14265.1 EPR79670.1 - 0.011 15.6 1.5 0.018 14.9 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF4391 PF14335.1 EPR79670.1 - 0.011 15.0 1.2 0.018 14.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF3573 PF12097.3 EPR79670.1 - 0.025 13.2 0.7 0.036 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4297 PF14130.1 EPR79670.1 - 0.034 14.1 2.1 0.052 13.4 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) Bac_small_YrzI PF09501.5 EPR79670.1 - 0.046 13.6 2.9 0.081 12.8 1.6 1.8 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DUF4477 PF14780.1 EPR79670.1 - 0.049 13.0 0.3 0.069 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) IncA PF04156.9 EPR79670.1 - 0.12 11.9 2.2 0.16 11.5 1.5 1.1 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EPR79670.1 - 0.25 9.1 1.9 0.3 8.9 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EPR79670.1 - 0.28 11.4 4.0 0.18 12.0 1.4 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.1 EPR79670.1 - 0.35 10.8 3.9 0.6 10.1 2.7 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Pox_A_type_inc PF04508.7 EPR79670.1 - 0.38 10.6 3.1 1.5 8.8 2.2 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DivIC PF04977.10 EPR79670.1 - 1.9 8.0 5.6 2.1 7.8 2.8 1.8 1 1 1 2 2 2 0 Septum formation initiator CDtoxinA PF03498.9 EPR79671.1 - 0.00043 19.6 0.2 0.00086 18.7 0.2 1.5 1 1 0 1 1 1 1 Cytolethal distending toxin A/C family RicinB_lectin_2 PF14200.1 EPR79671.1 - 0.0015 18.8 0.1 0.21 11.9 0.0 2.4 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EPR79671.1 - 0.003 17.6 0.0 0.0048 16.9 0.0 1.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain MBOAT PF03062.14 EPR79673.1 - 1.2e-07 31.2 40.9 1.2e-07 31.2 28.3 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPR79673.1 - 0.0027 17.7 4.8 0.0052 16.8 2.7 2.1 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1139 PF06599.6 EPR79674.1 - 0.46 9.5 7.9 4.3 6.4 0.2 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1139) CENP-M PF11111.3 EPR79674.1 - 0.5 9.5 3.2 19 4.4 0.1 2.9 2 1 1 3 3 3 0 Centromere protein M (CENP-M) MBOAT PF03062.14 EPR79675.1 - 4.3e-20 72.0 22.5 4.3e-20 72.0 15.6 2.2 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CBFD_NFYB_HMF PF00808.18 EPR79676.1 - 6.3e-21 74.2 2.2 1e-20 73.5 1.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR79676.1 - 0.00046 20.2 0.1 0.00083 19.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EPR79676.1 - 0.0033 17.1 0.1 0.0058 16.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated GlutR_N PF05201.10 EPR79676.1 - 0.051 13.1 0.2 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain DUF4375 PF14300.1 EPR79676.1 - 0.072 13.0 0.4 0.18 11.7 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) Phage_Mu_F PF04233.9 EPR79676.1 - 0.098 13.1 1.1 0.13 12.7 0.8 1.5 1 1 0 1 1 1 0 Phage Mu protein F like protein RNase_PH PF01138.16 EPR79677.1 - 3.5e-08 33.8 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 C6_DPF PF10170.4 EPR79678.1 - 0.0059 16.6 0.1 0.0074 16.3 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich domain Mem_trans PF03547.13 EPR79681.1 - 9.1 4.4 6.9 6.5 4.9 0.4 2.1 2 0 0 2 2 2 0 Membrane transport protein Cnd3 PF12719.2 EPR79682.1 - 0.021 13.8 1.7 0.031 13.2 0.0 2.1 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain VPS11_C PF12451.3 EPR79682.1 - 1.2 9.0 4.7 10 6.0 0.0 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal TLC PF03219.9 EPR79683.1 - 5.4e-56 190.0 45.3 6.5e-54 183.2 31.4 2.0 1 1 0 1 1 1 1 TLC ATP/ADP transporter DUF3671 PF12420.3 EPR79683.1 - 0.0054 16.6 2.8 0.0054 16.6 1.9 5.6 2 1 3 5 5 5 2 Protein of unknown function Abhydrolase_9_N PF15420.1 EPR79683.1 - 4.9 6.8 17.0 1.1 8.9 0.0 4.3 3 1 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus TLC PF03219.9 EPR79684.1 - 5.2e-63 213.2 35.6 4.5e-62 210.1 24.7 1.9 1 1 0 1 1 1 1 TLC ATP/ADP transporter KH_1 PF00013.24 EPR79685.1 - 2.1e-08 33.6 4.6 4.2e-08 32.7 1.9 2.2 1 1 1 2 2 2 1 KH domain KH_3 PF13014.1 EPR79685.1 - 0.0086 15.7 0.6 0.0086 15.7 0.4 2.5 3 0 0 3 3 3 1 KH domain XPG_I PF00867.13 EPR79686.1 - 2.9e-20 72.1 1.7 5.2e-20 71.3 0.4 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EPR79686.1 - 1.1e-19 70.5 0.1 4e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EPR79686.1 - 6.3e-05 23.1 0.2 0.0002 21.5 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.18 EPR79686.1 - 0.016 14.8 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif XPG_I_2 PF12813.2 EPR79686.1 - 0.087 12.3 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing GnsAB PF08178.6 EPR79687.1 - 0.078 12.6 3.1 8.6 6.1 0.0 3.1 1 1 1 3 3 3 0 GnsA/GnsB family WD40 PF00400.27 EPR79688.1 - 5.5e-30 102.1 7.6 1.6e-05 24.5 0.2 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPR79688.1 - 6.6e-10 39.0 4.5 0.00043 20.0 0.2 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A DBB PF14545.1 EPR79689.1 - 0.0025 17.3 1.0 0.0029 17.1 0.7 1.1 1 0 0 1 1 1 1 Dof, BCAP, and BANK (DBB) motif, Imm3 PF14425.1 EPR79689.1 - 0.02 14.8 1.7 0.02 14.8 1.2 1.7 1 1 1 2 2 2 0 Immunity protein Imm3 Vesiculo_matrix PF06326.7 EPR79689.1 - 0.056 12.8 0.4 0.068 12.6 0.3 1.1 1 0 0 1 1 1 0 Vesiculovirus matrix protein RRM_1 PF00076.17 EPR79690.1 - 5.8e-17 61.0 0.5 1.3e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR79690.1 - 3.6e-16 58.8 0.0 2.4e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79690.1 - 0.012 15.4 0.2 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 EPR79690.1 - 0.035 14.1 0.1 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Fer4_9 PF13187.1 EPR79690.1 - 0.8 10.0 4.5 0.42 10.9 0.6 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain PTPLA PF04387.9 EPR79691.1 - 8.8e-27 93.5 13.3 8.8e-27 93.5 9.2 2.5 2 1 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA E1-E2_ATPase PF00122.15 EPR79692.1 - 2.7e-23 82.2 3.0 2.7e-23 82.2 2.1 4.1 3 1 1 4 4 4 1 E1-E2 ATPase HAD PF12710.2 EPR79692.1 - 1.9e-17 64.0 4.6 3.9e-17 63.0 1.6 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EPR79692.1 - 9e-15 54.5 0.1 9e-15 54.5 0.1 3.0 3 0 0 3 3 3 1 P5-type ATPase cation transporter Hydrolase PF00702.21 EPR79692.1 - 6.4e-14 52.8 0.0 2.6e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPR79692.1 - 0.00053 19.8 0.8 0.0011 18.8 0.1 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit RNB PF00773.14 EPR79693.1 - 2.2e-80 270.3 13.2 2.2e-80 270.3 9.2 2.3 2 0 0 2 2 2 1 RNB domain DnaJ PF00226.26 EPR79694.1 - 1.1e-16 60.2 2.1 3.3e-16 58.7 1.5 1.9 1 0 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.19 EPR79695.1 - 2.6e-06 26.9 0.2 7.5e-06 25.5 0.2 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1850 PF08905.6 EPR79695.1 - 0.0035 17.1 0.1 0.0078 16.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1850) zf-CCCH_2 PF14608.1 EPR79695.1 - 4.3 7.4 10.6 1.8 8.7 2.3 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 EPR79696.1 - 3.4e-59 200.0 6.8 7.6e-59 198.9 0.1 2.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79696.1 - 3.2e-30 105.0 0.1 3.2e-30 105.0 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79696.1 - 1.8e-08 33.7 0.0 6.8e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like C1_1 PF00130.17 EPR79696.1 - 0.00012 21.7 10.9 0.00048 19.7 5.6 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 EPR79696.1 - 0.021 14.5 0.0 0.054 13.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Myosin_head PF00063.16 EPR79697.1 - 8.8e-232 770.9 15.1 8.8e-232 770.9 10.5 3.4 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.14 EPR79697.1 - 2.4e-11 43.1 4.4 1.3e-10 40.8 3.1 2.4 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IncA PF04156.9 EPR79697.1 - 0.0027 17.3 24.7 0.0027 17.3 17.1 7.9 1 1 6 7 7 7 4 IncA protein AAA_16 PF13191.1 EPR79697.1 - 0.021 14.7 2.5 0.058 13.3 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EPR79697.1 - 0.09 12.9 4.8 0.1 12.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain DNA_primase_S PF01896.14 EPR79698.1 - 5.6e-31 107.2 2.5 9.8e-31 106.5 1.8 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Autophagy_act_C PF03987.10 EPR79698.1 - 0.07 13.3 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain DUF496 PF04363.7 EPR79698.1 - 0.11 12.3 0.5 0.49 10.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF496) Ribosomal_S19 PF00203.16 EPR79699.1 - 4.6e-17 61.3 0.4 1.1e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S19 Sld5 PF05916.6 EPR79701.1 - 0.0088 16.3 2.4 0.013 15.7 1.6 1.4 1 0 0 1 1 1 1 GINS complex protein Syntaxin-6_N PF09177.6 EPR79701.1 - 0.22 11.9 3.0 0.25 11.7 1.5 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF3510 PF12022.3 EPR79701.1 - 0.22 11.6 4.5 0.14 12.2 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) DUF342 PF03961.8 EPR79701.1 - 0.5 8.7 8.1 0.61 8.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mitofilin PF09731.4 EPR79701.1 - 1.5 7.4 7.8 1.6 7.2 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein XisI PF08869.6 EPR79701.1 - 2.1 8.5 8.2 0.24 11.5 2.7 1.7 2 0 0 2 2 2 0 XisI protein KH_1 PF00013.24 EPR79702.1 - 1.4e-08 34.2 8.5 4.7e-08 32.5 2.6 2.6 2 1 0 2 2 2 2 KH domain KH_3 PF13014.1 EPR79702.1 - 0.00055 19.5 6.2 0.0007 19.1 1.5 2.5 2 0 0 2 2 2 1 KH domain SpoU_sub_bind PF08032.7 EPR79702.1 - 0.27 11.4 3.4 1.1 9.4 0.1 2.6 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Glycolytic PF00274.14 EPR79703.1 - 1e-96 323.3 0.0 1.2e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Histone PF00125.19 EPR79704.1 - 4.9e-16 58.6 1.1 9.4e-16 57.7 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPR79704.1 - 0.0059 16.6 0.5 0.027 14.5 0.1 2.2 2 2 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EPR79704.1 - 0.018 15.1 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Kinetochore component CENP-S Bromo_TP PF07524.8 EPR79704.1 - 0.03 14.0 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TAF PF02969.12 EPR79704.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) UPF0546 PF10639.4 EPR79704.1 - 0.13 12.1 0.2 0.22 11.3 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 RRM_1 PF00076.17 EPR79706.1 - 8.9e-12 44.4 0.1 1.7e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPR79706.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79706.1 - 2.3e-06 27.3 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S7e PF01251.13 EPR79708.1 - 8e-12 45.0 1.6 3.9e-10 39.5 1.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S7e AKAP7_RIRII_bdg PF10470.4 EPR79708.1 - 0.049 13.4 0.4 0.083 12.7 0.3 1.5 1 1 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein JAB PF01398.16 EPR79709.1 - 5.9e-31 106.5 0.1 1.1e-30 105.7 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPR79709.1 - 3.9e-12 46.2 0.1 1.6e-11 44.2 0.1 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EPR79709.1 - 2.4e-07 30.2 0.0 3.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EPR79709.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Nuf2 PF03800.9 EPR79710.1 - 2.5e-26 92.4 6.0 3.3e-26 92.0 2.1 2.8 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EPR79710.1 - 0.08 12.1 9.6 0.26 10.4 0.4 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EPR79710.1 - 2.4 5.3 42.3 3.5 4.8 29.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 EPR79710.1 - 4.7 6.7 50.8 0.6 9.6 8.3 3.2 1 1 1 3 3 3 0 IncA protein DnaJ PF00226.26 EPR79712.1 - 3.9e-24 84.1 7.6 7.1e-24 83.3 5.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPR79712.1 - 1.4e-11 44.0 1.1 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DUF4163 PF13739.1 EPR79712.1 - 4.3 8.1 9.0 0.59 10.9 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) S4 PF01479.20 EPR79714.1 - 2.1e-06 27.0 0.9 4.5e-06 25.9 0.6 1.6 1 0 0 1 1 1 1 S4 domain Ric8 PF10165.4 EPR79714.1 - 0.0096 14.7 0.6 0.011 14.6 0.4 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Ada3 PF10198.4 EPR79715.1 - 0.07 12.8 7.9 0.13 12.0 5.3 1.7 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 PSRP-3_Ycf65 PF04839.8 EPR79715.1 - 0.23 11.5 3.1 0.69 10.0 2.2 1.8 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Muskelin_N PF06588.6 EPR79716.1 - 4.4e-50 170.1 7.9 8.8e-50 169.1 5.5 1.5 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 EPR79716.1 - 2.9e-16 59.1 0.1 0.0026 17.8 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EPR79716.1 - 2e-14 53.1 0.4 0.0012 18.7 0.1 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EPR79716.1 - 8.4e-10 38.3 3.6 0.48 10.6 0.0 6.0 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 EPR79716.1 - 9.2e-09 34.9 5.7 0.022 14.5 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain F5_F8_type_C PF00754.20 EPR79716.1 - 3.5e-07 30.1 0.8 7.3e-07 29.0 0.5 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.10 EPR79716.1 - 4.8e-06 26.1 1.2 0.012 15.3 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EPR79716.1 - 0.0011 18.4 9.0 0.61 9.6 0.0 5.5 6 0 0 6 6 6 2 Kelch motif L27_2 PF09045.5 EPR79716.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 L27_2 FAT PF02259.18 EPR79717.1 - 4.3e-21 75.2 6.8 4.3e-21 75.2 4.7 2.2 2 0 0 2 2 2 1 FAT domain SET PF00856.23 EPR79718.1 - 2.5e-20 73.4 3.0 5.2e-20 72.3 0.8 2.5 2 1 0 2 2 2 1 SET domain UFD1 PF03152.9 EPR79719.1 - 3.2e-37 127.3 0.0 4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DEAD PF00270.24 EPR79720.1 - 9.6e-22 77.2 0.0 1.4e-20 73.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79720.1 - 4.5e-20 71.2 0.0 1.7e-18 66.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LRR_4 PF12799.2 EPR79721.1 - 4.2e-30 102.8 51.2 4.7e-05 22.9 0.1 10.0 7 2 0 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79721.1 - 9.1e-20 70.1 56.5 2.6e-07 30.2 5.7 9.9 9 2 2 11 11 11 6 Leucine rich repeat LRR_1 PF00560.28 EPR79721.1 - 2.9e-12 44.8 54.5 1.6 9.0 0.1 15.2 16 1 0 16 16 16 7 Leucine Rich Repeat LRR_7 PF13504.1 EPR79721.1 - 0.014 15.4 48.9 2.6 8.6 0.0 14.6 16 0 0 16 16 16 0 Leucine rich repeat LRR_6 PF13516.1 EPR79721.1 - 0.82 9.9 44.1 11 6.4 0.6 11.7 12 0 0 12 12 12 0 Leucine Rich repeat Tubulin_C PF03953.12 EPR79722.1 - 7.5e-17 61.5 0.4 1.1e-16 61.0 0.2 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Turandot PF07240.6 EPR79722.1 - 0.0026 17.2 0.6 0.005 16.3 0.4 1.4 1 0 0 1 1 1 1 Stress-inducible humoral factor Turandot Imm27 PF15573.1 EPR79722.1 - 0.053 12.7 0.6 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 27 UPF0223 PF05256.7 EPR79722.1 - 0.053 13.6 0.7 0.32 11.1 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) DUF663 PF04950.7 EPR79723.1 - 2.1e-21 76.1 11.1 2.1e-21 76.1 7.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF663) DUF1565 PF07602.6 EPR79723.1 - 0.89 8.6 11.9 0.045 12.8 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) DUF4451 PF14616.1 EPR79725.1 - 2.7e-22 78.8 11.9 1.6e-21 76.3 8.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) C1_1 PF00130.17 EPR79725.1 - 0.049 13.3 2.1 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_jaz PF12171.3 EPR79725.1 - 4.2 7.6 7.0 6 7.1 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EPR79725.1 - 4.5 7.8 10.8 2.2 8.7 1.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Med26 PF08711.6 EPR79726.1 - 1.2e-14 53.5 0.0 2.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Clat_adaptor_s PF01217.15 EPR79727.1 - 1.6e-09 37.6 3.1 2.1e-09 37.2 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TAF PF02969.12 EPR79728.1 - 2.6e-18 65.7 0.1 6.4e-18 64.4 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EPR79728.1 - 9.8e-18 64.0 0.0 2.2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) CBFD_NFYB_HMF PF00808.18 EPR79728.1 - 0.00048 20.1 0.1 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR79728.1 - 0.008 16.2 0.1 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2392 PF10288.4 EPR79728.1 - 0.74 10.1 5.3 1.6 9.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2392) Ribosomal_L44 PF00935.14 EPR79729.1 - 3.4e-24 84.6 10.8 5e-24 84.1 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Tombus_P33 PF08500.5 EPR79729.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Tombusvirus p33 RNA_POL_M_15KD PF02150.11 EPR79729.1 - 0.25 11.0 1.9 17 5.2 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Cript PF10235.4 EPR79729.1 - 0.6 10.4 6.1 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Tubulin PF00091.20 EPR79730.1 - 1.2e-67 227.8 0.1 1.4e-67 227.6 0.1 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 EPR79730.1 - 0.0002 21.4 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 EPR79730.1 - 0.029 13.3 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Sec66 PF09802.4 EPR79731.1 - 0.0084 15.5 7.2 0.016 14.5 4.6 1.6 1 1 1 2 2 2 1 Preprotein translocase subunit Sec66 Phi-29_GP16_7 PF06720.6 EPR79731.1 - 0.028 14.1 0.1 0.028 14.1 0.1 1.9 2 2 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 TRAP-gamma PF07074.7 EPR79731.1 - 0.11 12.0 1.1 0.18 11.2 0.8 1.6 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) zf-RING_2 PF13639.1 EPR79732.1 - 2.2e-10 40.1 4.3 3.6e-10 39.4 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPR79732.1 - 4.3e-07 29.8 5.7 1e-06 28.6 4.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPR79732.1 - 7.7e-07 29.1 2.6 1.6e-06 28.1 1.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPR79732.1 - 1.8e-06 27.5 4.3 3.4e-06 26.6 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPR79732.1 - 5.1e-06 26.0 5.1 1.2e-05 24.8 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPR79732.1 - 1.5e-05 24.7 4.1 4.6e-05 23.2 2.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPR79732.1 - 0.00013 21.5 4.7 0.0004 20.0 3.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EPR79732.1 - 0.00044 19.7 0.9 0.0013 18.2 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CENP-F_leu_zip PF10473.4 EPR79732.1 - 0.003 17.4 1.6 0.0057 16.5 1.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_3 PF13920.1 EPR79732.1 - 0.0064 16.1 5.5 0.017 14.7 3.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Augurin PF15187.1 EPR79732.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 zf-Apc11 PF12861.2 EPR79732.1 - 0.13 12.0 2.5 0.28 11.0 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2340 PF10209.4 EPR79732.1 - 4.9 7.3 18.6 4.9 7.3 4.1 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2340) PI3_PI4_kinase PF00454.22 EPR79735.1 - 0.028 13.8 0.3 0.028 13.8 0.2 2.3 3 0 0 3 3 3 0 Phosphatidylinositol 3- and 4-kinase PhageMin_Tail PF10145.4 EPR79735.1 - 0.057 13.0 0.5 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein SPT16 PF08644.6 EPR79735.1 - 3.3 7.5 14.6 0.99 9.2 7.2 2.2 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) TAF8_C PF10406.4 EPR79736.1 - 3.7e-09 36.4 0.4 7.2e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EPR79736.1 - 0.017 14.8 0.2 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated ADK PF00406.17 EPR79736.1 - 0.11 12.4 1.0 0.18 11.6 0.7 1.4 1 1 0 1 1 1 0 Adenylate kinase Use1 PF09753.4 EPR79738.1 - 2.6e-05 23.8 2.5 2.9e-05 23.6 1.7 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF3508 PF12018.3 EPR79738.1 - 0.0098 14.9 2.7 0.012 14.6 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) ABC2_membrane_3 PF12698.2 EPR79738.1 - 0.018 14.0 0.5 0.021 13.8 0.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Transcrip_reg PF01709.15 EPR79738.1 - 0.024 13.7 2.9 0.032 13.3 2.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator TIP120 PF08623.5 EPR79738.1 - 0.024 14.2 3.2 0.03 13.9 2.2 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Prominin PF05478.6 EPR79738.1 - 0.026 12.1 2.7 0.03 11.8 1.9 1.0 1 0 0 1 1 1 0 Prominin UPF0118 PF01594.11 EPR79738.1 - 0.026 13.5 0.7 0.035 13.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 DUF4200 PF13863.1 EPR79738.1 - 0.037 13.9 10.2 0.019 14.9 5.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PGK PF00162.14 EPR79738.1 - 0.038 12.5 0.5 0.044 12.3 0.3 1.1 1 0 0 1 1 1 0 Phosphoglycerate kinase Baculo_PEP_C PF04513.7 EPR79738.1 - 0.072 12.9 1.7 0.085 12.6 1.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MUG113 PF13455.1 EPR79738.1 - 0.079 13.4 0.3 11 6.5 0.0 2.1 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 Borrelia_orfD PF02999.9 EPR79738.1 - 0.13 12.4 3.8 0.16 12.0 2.3 1.5 1 1 0 1 1 1 0 Borrelia orf-D family DUF3573 PF12097.3 EPR79738.1 - 0.21 10.1 6.4 1.1 7.8 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Syntaxin PF00804.20 EPR79738.1 - 0.31 11.2 6.7 0.4 10.8 4.6 1.3 1 0 0 1 1 1 0 Syntaxin NTS_2 PF15448.1 EPR79738.1 - 0.47 10.7 5.4 0.45 10.8 0.4 2.4 2 1 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein TPR_MLP1_2 PF07926.7 EPR79738.1 - 0.54 10.0 8.1 0.17 11.6 2.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.8 EPR79738.1 - 0.57 9.5 6.2 0.46 9.8 3.0 1.8 1 1 1 2 2 2 0 fzo-like conserved region DUF1664 PF07889.7 EPR79738.1 - 1 9.1 6.4 0.53 10.0 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF912 PF06024.7 EPR79738.1 - 9.8 6.3 9.9 83 3.3 6.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Thioredoxin PF00085.15 EPR79740.1 - 2.4e-14 52.8 0.8 1.8e-08 33.9 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EPR79740.1 - 1.5e-13 50.9 11.1 5.1e-09 36.1 0.3 4.1 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPR79740.1 - 1e-09 38.5 1.0 1.3e-05 25.3 0.1 3.8 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPR79740.1 - 0.00019 21.1 2.7 0.0039 16.9 0.4 2.9 3 0 0 3 3 3 1 Thioredoxin domain AhpC-TSA PF00578.16 EPR79740.1 - 0.00035 20.2 0.2 0.0033 17.1 0.0 2.6 4 0 0 4 4 4 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EPR79740.1 - 0.00085 19.4 2.3 0.13 12.4 0.0 4.3 4 2 1 5 5 5 1 Thioredoxin-like Redoxin PF08534.5 EPR79740.1 - 0.0028 17.1 1.7 0.0072 15.8 0.1 2.2 3 0 0 3 3 3 1 Redoxin HyaE PF07449.6 EPR79740.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE DUF836 PF05768.9 EPR79740.1 - 0.0083 16.3 0.9 0.024 14.8 0.2 2.1 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EPR79740.1 - 0.26 11.3 4.4 0.16 11.9 0.2 2.9 4 1 0 4 4 4 0 Glutaredoxin SH2 PF00017.19 EPR79741.1 - 0.019 14.7 0.4 0.3 10.9 0.0 2.5 2 0 0 2 2 2 0 SH2 domain Polysacc_deac_1 PF01522.16 EPR79742.1 - 1.1e-09 37.9 0.0 3.2e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase DARPP-32 PF05395.7 EPR79742.1 - 0.81 9.8 6.0 1.3 9.2 4.1 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 RRN3 PF05327.6 EPR79742.1 - 3.6 5.5 9.0 5.2 5.0 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cpn60_TCP1 PF00118.19 EPR79744.1 - 8.5e-45 153.2 4.0 8.5e-45 153.2 2.8 2.0 1 1 1 2 2 2 1 TCP-1/cpn60 chaperonin family BRCT PF00533.21 EPR79744.1 - 0.06 13.4 0.2 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain SNARE PF05739.14 EPR79746.1 - 0.0007 19.2 4.8 0.0007 19.2 3.3 2.8 3 0 0 3 3 3 1 SNARE domain Laminin_II PF06009.7 EPR79746.1 - 0.0056 16.4 10.0 0.2 11.3 4.0 2.2 2 0 0 2 2 2 2 Laminin Domain II Vps51 PF08700.6 EPR79746.1 - 0.094 12.5 0.5 0.094 12.5 0.3 3.3 2 2 1 3 3 3 0 Vps51/Vps67 Synaptobrevin PF00957.16 EPR79746.1 - 0.11 12.1 8.0 0.03 13.9 3.1 2.0 2 0 0 2 2 2 0 Synaptobrevin Raptor_N PF14538.1 EPR79746.1 - 0.11 12.3 1.0 0.23 11.3 0.4 1.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Nup88 PF10168.4 EPR79746.1 - 0.3 8.9 12.3 0.35 8.6 8.5 1.1 1 0 0 1 1 1 0 Nuclear pore component PDGF_N PF04692.8 EPR79746.1 - 0.34 11.4 2.2 0.77 10.2 1.3 1.7 1 1 0 1 1 1 0 Platelet-derived growth factor, N terminal region Tropomyosin_1 PF12718.2 EPR79746.1 - 0.45 10.3 13.6 0.055 13.3 3.6 2.5 1 1 1 2 2 2 0 Tropomyosin like Cactin_mid PF10312.4 EPR79746.1 - 0.74 9.0 10.9 0.76 9.0 5.9 1.9 1 1 1 2 2 2 0 Conserved mid region of cactin FliT PF05400.8 EPR79746.1 - 1.5 9.2 5.0 2 8.8 2.6 1.9 2 0 0 2 2 2 0 Flagellar protein FliT TMPIT PF07851.8 EPR79746.1 - 1.8 7.5 10.4 0.35 9.8 4.1 1.9 2 0 0 2 2 2 0 TMPIT-like protein DUF2116 PF09889.4 EPR79746.1 - 2 8.2 5.5 0.63 9.8 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TMCO5 PF14992.1 EPR79746.1 - 2.5 7.1 19.2 1.7 7.6 12.2 1.6 1 1 0 1 1 1 0 TMCO5 family IncA PF04156.9 EPR79746.1 - 3.2 7.3 12.5 6.5 6.3 0.2 2.3 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 EPR79746.1 - 5.9 5.7 8.8 6 5.7 4.4 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MFS_1 PF07690.11 EPR79748.1 - 6.6e-28 97.4 47.4 1.2e-23 83.4 11.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPR79748.1 - 0.0013 17.4 23.2 0.0016 17.0 4.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter ESSS PF10183.4 EPR79748.1 - 0.29 11.5 0.1 0.29 11.5 0.0 3.7 4 1 1 5 5 5 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) IncA PF04156.9 EPR79748.1 - 0.38 10.3 0.0 0.38 10.3 0.0 3.7 5 0 0 5 5 5 0 IncA protein SET PF00856.23 EPR79749.1 - 0.023 14.9 0.6 0.82 9.9 0.1 2.1 1 1 1 2 2 2 0 SET domain Pkinase PF00069.20 EPR79750.1 - 4.1e-42 144.1 0.9 4.1e-42 144.1 0.6 2.3 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79750.1 - 1.7e-25 89.5 0.0 3.6e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79750.1 - 4.7e-09 35.6 0.1 9.1e-09 34.6 0.1 1.5 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 EPR79750.1 - 0.0023 17.3 0.2 0.0023 17.3 0.1 2.0 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 APH PF01636.18 EPR79750.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GAD PF02938.9 EPR79750.1 - 0.084 13.0 0.0 0.5 10.5 0.1 2.3 2 0 0 2 2 2 0 GAD domain AAA PF00004.24 EPR79751.1 - 2e-95 316.0 0.0 7.4e-47 158.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPR79751.1 - 6.9e-14 51.7 0.0 2.2e-05 24.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPR79751.1 - 2.4e-13 49.6 0.0 1.9e-05 23.8 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPR79751.1 - 5.1e-12 46.1 1.1 0.00015 21.8 0.0 4.0 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EPR79751.1 - 1.1e-11 44.9 0.2 0.00088 19.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPR79751.1 - 3e-11 44.1 0.3 0.00056 20.7 0.2 3.6 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EPR79751.1 - 1.2e-10 41.5 0.0 0.00044 20.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EPR79751.1 - 1.7e-10 40.9 0.0 0.00025 20.9 0.0 3.1 2 1 1 3 3 2 2 AAA domain AAA_14 PF13173.1 EPR79751.1 - 2.7e-09 36.9 0.0 0.0021 17.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EPR79751.1 - 2.7e-08 33.1 0.0 0.0063 15.6 0.0 2.9 2 1 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 EPR79751.1 - 5e-08 32.5 0.1 0.005 16.5 0.1 3.0 3 0 0 3 3 2 2 Part of AAA domain TIP49 PF06068.8 EPR79751.1 - 1e-07 31.0 0.0 0.0071 15.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus ABC_tran PF00005.22 EPR79751.1 - 2.1e-07 31.3 1.9 0.006 16.8 0.0 3.3 3 1 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.12 EPR79751.1 - 3.6e-07 29.7 0.1 0.0055 16.1 0.0 3.2 2 1 1 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 EPR79751.1 - 4.9e-07 30.1 0.0 0.056 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPR79751.1 - 5.5e-07 29.7 0.0 0.0029 17.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 EPR79751.1 - 1.1e-06 28.5 0.0 0.93 9.1 0.0 4.2 2 2 2 4 4 4 1 Archaeal ATPase AAA_25 PF13481.1 EPR79751.1 - 1.6e-06 27.6 3.4 0.069 12.5 0.1 4.0 2 2 1 3 3 3 2 AAA domain AAA_28 PF13521.1 EPR79751.1 - 1.8e-06 28.0 0.0 0.1 12.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain NTPase_1 PF03266.10 EPR79751.1 - 2.2e-06 27.4 0.8 0.93 9.1 0.0 4.5 3 1 1 4 4 4 1 NTPase DUF815 PF05673.8 EPR79751.1 - 3e-06 26.3 0.0 0.054 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EPR79751.1 - 9.9e-06 24.8 0.2 0.018 14.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EPR79751.1 - 1.2e-05 25.1 0.1 0.041 13.7 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EPR79751.1 - 1.4e-05 24.7 0.0 0.077 12.5 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 EPR79751.1 - 2.7e-05 23.9 0.0 0.064 12.8 0.0 2.7 2 0 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 EPR79751.1 - 4.4e-05 23.2 0.0 0.13 11.8 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.1 EPR79751.1 - 5e-05 22.9 0.0 0.053 13.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EPR79751.1 - 8.9e-05 22.0 0.0 0.22 10.9 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EPR79751.1 - 9.3e-05 21.4 0.0 0.038 12.8 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EPR79751.1 - 0.00012 22.4 3.9 1.9 8.7 0.0 3.6 3 0 0 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 EPR79751.1 - 0.00019 21.4 0.0 0.73 9.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EPR79751.1 - 0.0004 20.0 0.0 0.36 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EPR79751.1 - 0.00054 19.5 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EPR79751.1 - 0.00059 18.7 0.1 0.37 9.5 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain CDC48_N PF02359.13 EPR79751.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain UPF0079 PF02367.12 EPR79751.1 - 0.0032 17.1 0.0 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EPR79751.1 - 0.0032 17.0 0.0 0.66 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EPR79751.1 - 0.0035 16.8 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EPR79751.1 - 0.0055 15.4 0.0 1.4 7.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EPR79751.1 - 0.0092 15.1 1.3 2.1 7.4 0.0 3.3 2 1 1 3 3 3 1 KaiC AAA_29 PF13555.1 EPR79751.1 - 0.013 15.0 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.11 EPR79751.1 - 0.016 14.4 0.0 0.68 9.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 EPR79751.1 - 0.019 14.3 0.5 3.4 7.0 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain T2SE PF00437.15 EPR79751.1 - 0.022 13.6 0.0 7 5.4 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 EPR79751.1 - 0.027 13.4 0.0 3.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EPR79751.1 - 0.035 13.7 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.4 EPR79751.1 - 0.036 13.5 0.0 6.5 6.2 0.0 3.0 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EPR79751.1 - 0.041 13.8 0.1 4 7.4 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 EPR79751.1 - 0.052 13.0 0.0 6.3 6.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AFG1_ATPase PF03969.11 EPR79751.1 - 0.055 12.2 0.0 3.4 6.3 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Vps4_C PF09336.5 EPR79751.1 - 0.077 12.8 0.1 0.53 10.2 0.0 2.4 2 1 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF3356 PF11836.3 EPR79751.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) Ank PF00023.25 EPR79752.1 - 0.061 13.1 0.4 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat DUF2435 PF10363.4 EPR79752.1 - 0.66 9.9 3.4 7.3 6.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) SWIM PF04434.12 EPR79753.1 - 4.1e-09 35.7 0.3 8.5e-09 34.7 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF1456 PF07308.8 EPR79753.1 - 0.00026 20.9 0.3 0.00098 19.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) DBD_Tnp_Mut PF03108.10 EPR79753.1 - 0.012 15.1 2.2 0.028 13.9 1.5 1.7 1 0 0 1 1 1 0 MuDR family transposase G_glu_transpept PF01019.16 EPR79754.1 - 8.8e-141 469.8 0.0 1e-140 469.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pam16 PF03656.8 EPR79755.1 - 8.5e-07 28.8 0.2 9.8e-07 28.6 0.2 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 EPR79755.1 - 6.8e-05 22.5 0.5 8.9e-05 22.1 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain DUF3819 PF12842.2 EPR79756.1 - 1.6e-07 31.0 4.7 7.6e-06 25.6 0.1 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3819) PI3_PI4_kinase PF00454.22 EPR79758.1 - 8.5e-32 110.5 1.0 2.2e-31 109.1 0.7 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPR79758.1 - 7.7e-10 38.0 1.2 1.3e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 FATC domain RRM_6 PF14259.1 EPR79759.1 - 2.8e-10 40.0 0.3 0.00023 21.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPR79759.1 - 2.1e-07 30.4 2.2 0.0024 17.4 0.1 2.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79759.1 - 5.4e-06 26.1 0.8 0.048 13.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dynamin_N PF00350.18 EPR79760.1 - 2.7e-33 115.1 3.3 2.7e-33 115.1 2.3 2.8 2 2 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EPR79760.1 - 1.3e-18 66.8 23.7 1.3e-18 66.8 16.4 2.1 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EPR79760.1 - 2.1e-05 24.4 1.6 0.0011 18.9 1.1 3.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPR79760.1 - 0.0012 18.0 8.6 0.23 10.6 0.0 3.9 3 1 0 4 4 4 2 Signal recognition particle receptor beta subunit Miro PF08477.8 EPR79760.1 - 0.0024 18.3 0.1 0.014 15.8 0.1 2.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EPR79760.1 - 0.0049 16.3 0.7 3.5 7.1 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EPR79760.1 - 0.047 13.6 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPR79760.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CALCOCO1 PF07888.6 EPR79761.1 - 0.0058 14.9 27.0 0.0078 14.5 18.7 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF869 PF05911.6 EPR79761.1 - 0.36 9.0 28.4 0.42 8.7 19.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Helicase_C_2 PF13307.1 EPR79762.1 - 1.3e-46 158.6 2.5 2.6e-46 157.6 0.0 2.6 1 1 1 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EPR79762.1 - 5.4e-39 133.3 0.8 5.4e-39 133.3 0.5 2.9 3 0 0 3 3 3 1 DEAD_2 AAA_19 PF13245.1 EPR79762.1 - 0.14 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Septin PF00735.13 EPR79765.1 - 1e-49 169.1 15.4 5.3e-38 130.6 8.8 2.7 2 1 0 2 2 2 2 Septin Miro PF08477.8 EPR79765.1 - 0.0023 18.4 0.3 0.0076 16.7 0.2 2.0 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EPR79765.1 - 0.0036 17.5 2.6 0.0072 16.6 1.8 1.7 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EPR79765.1 - 0.012 15.4 0.3 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPR79765.1 - 0.024 14.0 0.4 0.054 12.9 0.2 1.5 1 1 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EPR79765.1 - 0.035 13.2 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EPR79765.1 - 0.094 12.6 1.8 0.12 12.3 0.3 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EPR79765.1 - 0.18 11.9 4.6 2.1 8.5 0.0 3.1 3 2 1 4 4 4 0 RNA helicase SRP54 PF00448.17 EPR79766.1 - 1.1e-69 233.8 0.5 1.8e-69 233.1 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EPR79766.1 - 8.2e-22 77.4 3.0 1.3e-21 76.8 0.5 2.5 2 1 0 2 2 2 1 Signal peptide binding domain cobW PF02492.14 EPR79766.1 - 3.2e-08 33.2 1.0 8.6e-08 31.8 0.3 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRP54_N PF02881.14 EPR79766.1 - 6.1e-07 29.4 0.6 1.9e-06 27.9 0.4 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MobB PF03205.9 EPR79766.1 - 0.00082 19.0 0.3 0.0053 16.4 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPR79766.1 - 0.0022 17.8 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPR79766.1 - 0.0025 17.9 0.0 0.0091 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 EPR79766.1 - 0.019 14.1 0.1 3.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ArgK PF03308.11 EPR79766.1 - 0.025 13.3 0.1 0.13 11.0 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_30 PF13604.1 EPR79766.1 - 0.034 13.7 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain XkdN PF08890.6 EPR79766.1 - 0.087 12.5 2.5 8.9 6.0 0.2 2.5 2 0 0 2 2 2 0 Phage XkdN-like protein DUF1160 PF06648.6 EPR79766.1 - 0.14 11.9 1.4 3.3 7.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) Ribosomal_S6e PF01092.14 EPR79767.1 - 2e-12 46.8 0.4 2e-12 46.8 0.3 1.8 2 1 0 2 2 2 1 Ribosomal protein S6e DUF4337 PF14235.1 EPR79767.1 - 0.44 10.3 3.6 0.65 9.8 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PseudoU_synth_2 PF00849.17 EPR79768.1 - 7e-28 97.5 0.0 1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.13 EPR79768.1 - 0.008 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TGS PF02824.16 EPR79768.1 - 0.016 15.0 0.5 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 TGS domain PAP2_C PF14360.1 EPR79769.1 - 5.8e-17 61.7 10.9 5.8e-17 61.7 7.6 3.1 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EPR79769.1 - 4.8e-05 23.0 12.7 0.00041 20.0 8.8 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EPR79769.1 - 2.1 7.8 12.1 0.34 10.4 5.6 1.7 2 1 0 2 2 2 0 PAP2 superfamily SNARE PF05739.14 EPR79770.1 - 0.0044 16.6 0.4 0.0044 16.6 0.3 3.3 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 EPR79770.1 - 0.36 10.9 7.5 0.79 9.8 2.3 3.2 3 1 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Spt4 PF06093.8 EPR79772.1 - 8e-22 76.9 2.1 1.4e-19 69.7 1.5 2.1 1 1 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EPR79772.1 - 0.039 13.7 0.2 0.083 12.7 0.1 1.6 2 0 0 2 2 2 0 Coronavirus gene 5 protein TBCC PF07986.7 EPR79772.1 - 0.12 11.7 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C HAD_2 PF13419.1 EPR79773.1 - 2.6e-10 40.7 0.0 2.7e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EPR79773.1 - 0.017 15.3 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPR79773.1 - 0.036 13.7 5.3 0.27 10.8 0.7 2.7 2 1 0 2 2 2 0 Acid Phosphatase Nitro_FeMo-Co PF02579.12 EPR79773.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor DUF3641 PF12345.3 EPR79773.1 - 0.19 11.5 2.4 0.89 9.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) Wzz PF02706.10 EPR79774.1 - 0.15 11.9 3.2 1.5 8.5 2.3 2.7 2 0 0 2 2 2 0 Chain length determinant protein LRR_4 PF12799.2 EPR79776.1 - 6.3e-21 73.5 65.9 8.9e-07 28.3 0.3 10.4 6 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79776.1 - 3.8e-19 68.1 54.2 1.4e-06 27.9 1.6 8.3 5 3 2 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 EPR79776.1 - 1.3e-07 30.6 42.9 0.25 11.5 0.0 12.9 13 1 1 14 14 14 6 Leucine Rich Repeat LRR_9 PF14580.1 EPR79776.1 - 0.0013 18.3 17.2 0.036 13.6 1.0 3.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 EPR79776.1 - 0.01 15.8 36.1 2 8.9 0.1 11.9 14 0 0 14 14 14 0 Leucine rich repeat DUF2615 PF11027.3 EPR79776.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Peptidase_M18 PF02127.10 EPR79777.1 - 4.8e-84 282.3 0.9 6.4e-57 192.9 0.1 2.0 1 1 1 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EPR79777.1 - 2.2e-06 26.6 0.1 6.5e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase DUF2663 PF10864.3 EPR79778.1 - 7 6.8 9.2 0.44 10.7 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) zf-CCCH PF00642.19 EPR79780.1 - 4.5e-16 58.0 14.5 3.4e-11 42.5 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPR79780.1 - 0.0057 16.5 0.7 0.0057 16.5 0.5 2.8 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type DUF1460 PF07313.7 EPR79780.1 - 0.16 11.1 7.5 0.91 8.6 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1460) YebO PF13974.1 EPR79780.1 - 1.7 8.4 6.1 1 9.1 0.4 2.4 2 0 0 2 2 2 0 YebO-like protein ABC_tran PF00005.22 EPR79781.1 - 1.4e-29 103.1 0.1 2.7e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EPR79781.1 - 1.4e-10 41.0 18.0 2e-10 40.5 12.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EPR79781.1 - 1.9e-06 27.2 2.5 2.1e-05 23.9 1.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPR79781.1 - 2.8e-06 27.5 5.4 2.8e-06 27.5 3.7 4.3 2 2 1 3 3 2 1 AAA domain ABC_ATPase PF09818.4 EPR79781.1 - 3.5e-06 25.8 0.2 0.00013 20.6 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 EPR79781.1 - 0.00041 19.9 0.3 0.00075 19.0 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 EPR79781.1 - 0.0087 15.5 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EPR79781.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EPR79781.1 - 0.023 13.8 1.2 0.055 12.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EPR79781.1 - 0.044 14.2 0.2 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EPR79781.1 - 0.058 12.4 0.2 0.058 12.4 0.1 4.1 2 1 2 4 4 3 0 AAA ATPase domain AAA_17 PF13207.1 EPR79781.1 - 0.1 13.3 2.3 0.64 10.8 1.6 2.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EPR79781.1 - 0.54 10.2 3.8 2.8 7.9 2.6 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase PLAC8 PF04749.12 EPR79781.1 - 1.4 9.5 4.3 0.9 10.1 0.8 2.2 1 1 0 2 2 2 0 PLAC8 family RRM_6 PF14259.1 EPR79782.1 - 1.9e-08 34.1 0.1 4.6e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPR79782.1 - 2.1e-08 33.6 0.0 3.7e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79782.1 - 8.4e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MS_channel PF00924.13 EPR79783.1 - 2.4e-19 69.5 6.1 2.4e-19 69.5 4.3 2.3 3 0 0 3 3 3 1 Mechanosensitive ion channel DUF639 PF04842.7 EPR79785.1 - 0.025 12.7 4.9 0.11 10.6 3.2 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) EMP24_GP25L PF01105.19 EPR79785.1 - 4.2 7.0 7.5 0.61 9.7 1.8 2.1 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD LRR_4 PF12799.2 EPR79785.1 - 5.6 6.7 12.3 0.25 10.9 3.8 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ERCC4 PF02732.10 EPR79786.1 - 3.2e-13 49.6 0.5 1.2e-12 47.8 0.2 2.2 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.1 EPR79786.1 - 0.046 13.9 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain DnaJ PF00226.26 EPR79787.1 - 0.0018 17.9 0.5 0.0036 17.0 0.0 1.8 2 1 0 2 2 2 1 DnaJ domain DUF973 PF06157.6 EPR79787.1 - 0.015 14.2 0.2 0.02 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Serinc PF03348.10 EPR79787.1 - 0.018 13.7 0.2 0.026 13.2 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF999 PF06198.6 EPR79787.1 - 0.03 14.1 1.0 0.038 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF999) V-SNARE_C PF12352.3 EPR79788.1 - 0.00012 22.0 0.2 0.00021 21.3 0.1 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EPR79788.1 - 0.0012 18.5 1.6 0.051 13.2 0.1 2.2 2 0 0 2 2 2 1 Sec20 DUF106 PF01956.11 EPR79788.1 - 0.0031 17.0 0.6 0.0045 16.5 0.4 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 MMPL PF03176.10 EPR79788.1 - 0.013 14.2 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 MMPL family ParcG PF10274.4 EPR79788.1 - 0.13 12.1 1.5 0.2 11.5 1.0 1.3 1 0 0 1 1 1 0 Parkin co-regulated protein DUF843 PF05814.6 EPR79788.1 - 0.25 11.1 4.8 0.15 11.8 0.8 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Tweety PF04906.8 EPR79788.1 - 0.27 9.6 2.5 1.7 6.9 0.1 2.1 1 1 1 2 2 2 0 Tweety ECM11 PF15463.1 EPR79788.1 - 0.37 11.0 4.6 0.16 12.2 1.0 1.8 2 0 0 2 2 2 0 Extracellular mutant protein 11 Syntaxin-6_N PF09177.6 EPR79788.1 - 0.45 10.9 3.4 0.56 10.6 0.6 2.1 1 1 0 2 2 2 0 Syntaxin 6, N-terminal AAA PF00004.24 EPR79789.1 - 4.6e-42 143.3 0.0 7.8e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPR79789.1 - 3.2e-06 27.3 1.0 0.001 19.2 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EPR79789.1 - 1.7e-05 24.7 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPR79789.1 - 4.2e-05 23.2 0.2 0.00023 20.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EPR79789.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPR79789.1 - 0.00025 21.0 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPR79789.1 - 0.00095 18.2 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPR79789.1 - 0.0014 18.5 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPR79789.1 - 0.0016 19.2 0.1 0.0037 18.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPR79789.1 - 0.0019 17.8 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPR79789.1 - 0.0033 17.2 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPR79789.1 - 0.0075 15.1 0.0 0.074 11.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 EPR79789.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EPR79789.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EPR79789.1 - 0.018 14.4 0.4 0.32 10.3 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EPR79789.1 - 0.019 15.2 0.1 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPR79789.1 - 0.021 14.5 0.2 0.044 13.5 0.2 1.4 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EPR79789.1 - 0.022 13.8 0.3 0.79 8.7 0.0 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.17 EPR79789.1 - 0.023 14.8 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 EPR79789.1 - 0.041 12.6 0.0 0.077 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 EPR79789.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EPR79789.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EPR79789.1 - 0.15 11.6 0.3 1.4 8.5 0.1 2.5 3 0 0 3 3 3 0 NACHT domain TruD PF01142.13 EPR79790.1 - 2e-44 151.8 3.4 3.1e-29 101.8 0.3 3.4 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) GLTSCR1 PF15249.1 EPR79791.1 - 2.2e-07 30.9 0.3 2.2e-07 30.9 0.2 2.0 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region HNF-1_N PF04814.8 EPR79791.1 - 0.23 11.5 4.0 0.82 9.7 2.8 1.9 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mur_ligase_M PF08245.7 EPR79791.1 - 1.6 8.7 6.2 0.37 10.7 1.3 2.1 1 1 0 2 2 2 0 Mur ligase middle domain Ribosomal_L17 PF01196.14 EPR79791.1 - 4 8.0 6.6 7.2 7.2 4.5 1.8 1 1 0 1 1 1 0 Ribosomal protein L17 EF-hand_like PF09279.6 EPR79791.1 - 5.4 7.1 11.2 7.2 6.7 0.2 3.9 1 1 2 4 4 4 0 Phosphoinositide-specific phospholipase C, efhand-like Sec16 PF12932.2 EPR79791.1 - 7.7 6.5 7.3 0.41 10.6 0.1 2.4 2 2 1 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region Sua5_yciO_yrdC PF01300.13 EPR79792.1 - 1.8e-46 157.6 0.0 3.8e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EPR79792.1 - 2.9e-25 88.7 0.1 4.3e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF1469 PF07332.6 EPR79793.1 - 0.37 10.5 2.3 0.44 10.2 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) LRR_8 PF13855.1 EPR79794.1 - 5.1e-05 22.9 0.7 5.1e-05 22.9 0.5 6.5 5 2 1 6 6 6 2 Leucine rich repeat LRR_4 PF12799.2 EPR79794.1 - 0.0078 15.8 27.4 0.073 12.7 0.1 6.9 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79794.1 - 0.012 15.5 21.5 5.3 7.4 0.1 8.9 8 2 1 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.1 EPR79794.1 - 0.12 12.4 11.1 15 6.0 0.1 6.1 6 1 0 6 6 6 0 Leucine Rich repeat DUF2522 PF10747.4 EPR79796.1 - 0.0018 18.3 0.5 0.002 18.1 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2522) DUF1749 PF08538.5 EPR79797.1 - 4.6e-25 88.1 0.0 9e-25 87.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 EPR79797.1 - 5.7e-09 35.8 0.0 1.6e-07 31.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPR79797.1 - 6.6e-08 32.7 0.0 7.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPR79797.1 - 1.2e-05 25.1 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EPR79797.1 - 0.0029 16.6 0.4 0.0044 16.0 0.0 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 EPR79797.1 - 0.0085 15.5 0.0 0.43 9.9 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EPR79797.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 EPR79797.1 - 0.075 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase zf-C2H2 PF00096.21 EPR79798.1 - 0.0057 16.9 2.5 0.0097 16.1 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type FdhD-NarQ PF02634.10 EPR79798.1 - 0.015 14.7 0.6 0.017 14.6 0.4 1.2 1 0 0 1 1 1 0 FdhD/NarQ family zf-C2H2_4 PF13894.1 EPR79798.1 - 0.029 14.7 0.9 0.048 14.0 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Ta0938 PF11494.3 EPR79798.1 - 0.035 14.2 0.6 0.076 13.1 0.1 1.7 2 0 0 2 2 2 0 Ta0938 zf-C2H2_2 PF12756.2 EPR79798.1 - 0.18 11.8 7.5 0.074 13.1 2.8 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Rad50_zn_hook PF04423.9 EPR79798.1 - 0.27 10.7 3.3 0.79 9.2 2.3 1.9 1 1 0 1 1 1 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.1 EPR79798.1 - 0.63 10.4 0.2 0.63 10.4 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain SAE2 PF08573.5 EPR79798.1 - 6.4 7.5 7.7 2.1 9.1 2.7 1.9 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Pkinase PF00069.20 EPR79799.1 - 7.9e-34 116.9 0.5 8.4e-34 116.8 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79799.1 - 3.5e-10 39.3 0.1 4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPR79799.1 - 0.00066 19.4 0.0 0.086 12.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EPR79799.1 - 0.049 12.6 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase YrbL-PhoP_reg PF10707.4 EPR79799.1 - 0.074 12.3 0.0 0.35 10.1 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EPR79799.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipoprotein_Ltp PF07553.6 EPR79799.1 - 0.13 12.0 1.4 0.53 10.1 0.9 2.0 1 0 0 1 1 1 0 Host cell surface-exposed lipoprotein TPR_11 PF13414.1 EPR79800.1 - 8.5e-27 92.6 6.9 4.7e-20 70.9 2.2 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPR79800.1 - 5.9e-15 54.1 16.7 1.8e-10 39.9 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPR79800.1 - 2.4e-11 42.6 14.4 1.3e-06 27.8 0.1 4.3 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPR79800.1 - 2.7e-09 37.4 0.0 1.2e-05 25.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPR79800.1 - 8.2e-09 34.9 4.8 0.0019 18.2 0.4 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPR79800.1 - 7.4e-07 29.2 0.0 0.037 14.6 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPR79800.1 - 6.9e-06 25.9 1.3 0.00027 20.8 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPR79800.1 - 2.9e-05 24.3 2.8 0.046 14.0 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPR79800.1 - 0.00012 21.6 22.6 0.00044 19.8 0.2 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPR79800.1 - 0.00036 20.0 3.9 3.8 7.5 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPR79800.1 - 0.0013 19.0 1.0 9.1 6.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPR79800.1 - 0.017 14.9 0.0 2.1 8.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat USP7_ICP0_bdg PF12436.3 EPR79800.1 - 0.019 14.1 0.7 0.019 14.1 0.5 2.0 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 DUF2989 PF11207.3 EPR79800.1 - 0.054 12.9 3.0 0.059 12.8 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2989) SHNi-TPR PF10516.4 EPR79800.1 - 0.073 12.3 0.1 2.9 7.2 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TOM20_plant PF06552.7 EPR79800.1 - 0.079 12.5 2.4 3.4 7.2 0.1 2.8 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Fis1_TPR_C PF14853.1 EPR79800.1 - 0.096 12.5 0.6 20 5.1 0.0 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EPR79800.1 - 0.1 12.7 4.6 0.44 10.7 0.5 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1911 PF08929.5 EPR79800.1 - 0.36 11.5 4.7 0.48 11.1 2.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1911) RPN7 PF10602.4 EPR79800.1 - 1.7 8.0 8.5 6.2 6.1 1.4 2.3 1 1 1 2 2 2 0 26S proteasome subunit RPN7 Tim17 PF02466.14 EPR79801.1 - 1.6e-14 54.0 3.4 2.3e-14 53.5 2.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 EPR79801.1 - 0.0034 17.0 0.8 2.3 7.8 0.2 2.1 2 0 0 2 2 2 2 Glycine-zipper containing OmpA-like membrane domain AcetylCoA_hyd_C PF13336.1 EPR79801.1 - 0.033 13.8 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Gly-zipper_YMGG PF13441.1 EPR79801.1 - 0.079 12.4 2.0 6.7 6.3 0.0 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EPR79801.1 - 2 8.1 4.7 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain RRM_6 PF14259.1 EPR79802.1 - 3.6e-09 36.4 0.0 6.4e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPR79802.1 - 1.3e-08 34.3 0.0 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPR79802.1 - 0.0023 17.7 0.2 0.0049 16.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EPR79802.1 - 0.0093 15.9 0.2 0.026 14.5 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif 2 UBX PF00789.15 EPR79804.1 - 0.0096 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain DNA_pol_B_3 PF08408.5 EPR79804.1 - 0.024 14.5 1.4 0.031 14.1 1.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B viral insert DNA_Packaging_2 PF11123.3 EPR79804.1 - 0.027 14.3 0.9 0.072 12.9 0.0 2.0 2 1 0 2 2 2 0 DNA packaging protein Merozoite_SPAM PF07133.6 EPR79804.1 - 0.042 13.7 8.4 0.057 13.3 5.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF4631 PF15450.1 EPR79804.1 - 0.08 11.2 7.9 0.097 10.9 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Vir_act_alpha_C PF10400.4 EPR79804.1 - 0.15 12.4 2.0 0.79 10.1 1.1 2.0 2 0 0 2 2 2 0 Virulence activator alpha C-term TcdA_TcdB PF12919.2 EPR79804.1 - 1.8 6.9 10.6 0.061 11.8 0.3 2.0 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain TatD_DNase PF01026.16 EPR79805.1 - 1.2e-39 136.0 0.0 2.4e-39 135.1 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase HSP90 PF00183.13 EPR79806.1 - 1.7e-135 452.4 34.8 2.1e-135 452.1 24.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EPR79806.1 - 3.7e-13 49.2 0.1 3.7e-13 49.2 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPR79806.1 - 5.4e-07 29.3 0.0 1.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_pol3_a_NII PF11490.3 EPR79806.1 - 0.11 12.1 20.3 0.11 12.0 7.9 2.9 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF912 PF06024.7 EPR79807.1 - 0.053 13.5 0.2 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 EPR79807.1 - 1.1 9.2 8.0 1.5 8.8 2.8 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3899 PF13038.1 EPR79807.1 - 2.8 8.1 5.4 13 6.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Peptidase_S8 PF00082.17 EPR79808.1 - 6.7e-48 163.2 6.6 2.8e-47 161.2 4.5 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EPR79808.1 - 0.021 15.3 1.6 0.021 15.3 1.1 2.1 2 0 0 2 2 2 0 Peptidase inhibitor I9 MCM PF00493.18 EPR79809.1 - 1.8e-133 444.4 0.1 2.7e-133 443.8 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPR79809.1 - 2.2e-20 73.3 1.8 2.2e-20 73.3 1.2 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPR79809.1 - 3e-09 36.3 0.1 3.2e-07 29.7 0.0 2.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPR79809.1 - 9.5e-07 28.6 0.0 2.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPR79809.1 - 0.00033 20.2 0.0 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPR79809.1 - 0.011 15.2 0.0 0.16 11.4 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Pkinase PF00069.20 EPR79810.1 - 5.2e-71 238.8 0.7 5.2e-71 238.8 0.5 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79810.1 - 3.6e-40 137.6 0.1 5.5e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79810.1 - 4.1e-09 35.8 0.0 5.1e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 EPR79810.1 - 1.1e-05 25.2 0.3 5.2e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 POLO box duplicated region APH PF01636.18 EPR79810.1 - 0.0067 16.1 0.0 0.25 11.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPR79810.1 - 0.027 13.7 10.4 0.067 12.5 0.6 3.2 2 1 1 3 3 3 0 RIO1 family TypeIII_RM_meth PF12564.3 EPR79810.1 - 0.23 11.4 6.0 2.9 7.9 0.1 3.7 3 0 0 3 3 3 0 Type III restriction/modification enzyme methylation subunit PGM_PMM_I PF02878.11 EPR79811.1 - 3.4e-17 62.2 0.0 9.7e-08 31.5 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EPR79811.1 - 7e-09 35.9 0.0 3.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPR79811.1 - 0.00083 19.3 0.0 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EPR79811.1 - 0.0039 17.1 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PPTA PF01239.17 EPR79812.1 - 0.075 12.4 0.1 0.23 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat BRI3BP PF14965.1 EPR79812.1 - 9.6 5.5 12.4 0.67 9.2 4.6 1.8 1 1 0 2 2 2 0 Negative regulator of p53/TP53 Cpn60_TCP1 PF00118.19 EPR79813.1 - 3.3e-131 438.2 14.0 3.9e-131 438.0 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myb_DNA-binding PF00249.26 EPR79814.1 - 4.6e-05 23.3 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPR79814.1 - 5.3e-05 23.2 0.1 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_3 PF13920.1 EPR79815.1 - 1e-06 28.3 8.5 1e-06 28.3 5.9 3.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPR79815.1 - 0.00062 19.5 10.2 0.00062 19.5 7.1 3.6 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPR79815.1 - 0.0026 17.7 12.6 0.0026 17.7 8.8 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR79815.1 - 0.0047 16.5 11.8 0.0047 16.5 8.2 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.2 EPR79815.1 - 0.013 15.6 0.4 0.013 15.6 0.3 5.3 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EPR79815.1 - 0.034 14.4 28.1 0.38 11.1 0.1 6.1 5 1 0 5 5 5 0 C2H2-type zinc finger Ribosomal_L32p PF01783.18 EPR79815.1 - 6.4 7.0 9.7 2.9 8.1 0.1 3.6 2 1 1 3 3 3 0 Ribosomal L32p protein family EMP24_GP25L PF01105.19 EPR79816.1 - 0.00092 18.9 0.3 0.0012 18.6 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PixA PF12306.3 EPR79816.1 - 0.076 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Inclusion body protein Glyco_transf_20 PF00982.16 EPR79817.1 - 3.3e-141 471.0 0.4 3.7e-141 470.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EPR79817.1 - 0.0002 20.9 0.1 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Septin PF00735.13 EPR79819.1 - 2.1e-71 240.2 1.0 2.6e-71 239.9 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPR79819.1 - 2.6e-08 33.8 0.1 5e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPR79819.1 - 8.1e-07 28.4 1.1 0.0008 18.6 0.0 2.4 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region AIG1 PF04548.11 EPR79819.1 - 3e-06 26.5 0.3 6.1e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EPR79819.1 - 2.5e-05 24.1 1.9 0.021 14.6 0.3 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPR79819.1 - 2.7e-05 24.6 0.1 5.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EPR79819.1 - 3.2e-05 23.1 0.0 6.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPR79819.1 - 0.00033 20.1 0.2 0.066 12.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.9 EPR79819.1 - 0.002 17.1 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 EPR79819.1 - 0.002 17.6 0.2 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EPR79819.1 - 0.0024 16.7 0.5 0.0052 15.6 0.0 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 EPR79819.1 - 0.0029 17.1 0.3 0.0029 17.1 0.2 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 EPR79819.1 - 0.0035 17.2 0.0 0.0081 16.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain FeoB_N PF02421.13 EPR79819.1 - 0.0094 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 EPR79819.1 - 0.014 14.8 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Ras family MobB PF03205.9 EPR79819.1 - 0.014 15.0 0.3 0.97 9.1 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EPR79819.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF313 PF03754.8 EPR79819.1 - 0.02 14.7 0.1 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF313) T2SE PF00437.15 EPR79819.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.7 EPR79819.1 - 0.023 13.9 0.2 0.045 13.0 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.1 EPR79819.1 - 0.026 14.0 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EPR79819.1 - 0.049 13.4 0.2 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 EPR79819.1 - 0.053 12.1 0.0 0.086 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EPR79819.1 - 0.06 12.7 0.2 0.3 10.5 0.0 2.1 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EPR79819.1 - 0.076 13.3 0.7 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EPR79819.1 - 0.09 11.8 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SRPRB PF09439.5 EPR79819.1 - 0.091 11.9 0.3 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EPR79819.1 - 0.11 13.3 0.1 0.23 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 EPR79820.1 - 2.2e-91 305.9 5.9 6e-91 304.5 4.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EPR79820.1 - 5.3e-74 249.4 6.4 5.3e-74 249.4 4.4 3.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EPR79820.1 - 3.3e-69 232.0 0.2 3.3e-69 232.0 0.2 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPR79820.1 - 2.7e-31 108.4 1.4 2.1e-30 105.5 0.1 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPR79820.1 - 3.7e-30 103.8 0.7 4.9e-29 100.2 0.0 3.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DsrD PF08679.6 EPR79820.1 - 0.0078 16.2 0.5 0.0078 16.2 0.3 4.4 4 0 0 4 4 4 1 Dissimilatory sulfite reductase D (DsrD) Tn7_Tnp_TnsA_C PF08721.6 EPR79820.1 - 0.013 15.4 1.8 0.99 9.4 0.1 3.0 2 0 0 2 2 2 0 TnsA endonuclease C terminal DUF1657 PF07870.6 EPR79820.1 - 0.038 13.6 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) zf-Sec23_Sec24 PF04810.10 EPR79821.1 - 8.2e-08 31.6 1.8 2e-07 30.4 1.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EPR79821.1 - 3.4e-07 29.6 1.3 8.6e-07 28.3 0.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPR79821.1 - 1.7e-06 28.4 0.2 4.7e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EPR79821.1 - 6.3e-05 22.5 0.3 0.00034 20.2 0.1 2.4 2 1 0 2 2 2 1 Gelsolin repeat HEAT_2 PF13646.1 EPR79822.1 - 0.00058 20.0 0.0 0.033 14.4 0.0 2.9 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.17 EPR79822.1 - 0.0046 16.9 0.0 2.4 8.4 0.0 4.1 4 1 1 5 5 5 1 HEAT repeat Repressor_Mnt PF11423.3 EPR79822.1 - 0.0067 15.7 0.0 0.02 14.1 0.0 1.8 1 0 0 1 1 1 1 Regulatory protein Mnt Cohesin_HEAT PF12765.2 EPR79822.1 - 0.026 14.4 0.1 0.69 9.9 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DnaB_2 PF07261.6 EPR79822.1 - 9.4 5.9 15.4 0.072 12.7 1.0 4.1 4 0 0 4 4 4 0 Replication initiation and membrane attachment Metallophos PF00149.23 EPR79823.1 - 4.8e-45 153.4 0.0 5.9e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.24 EPR79824.1 - 8e-31 106.9 0.2 2.1e-30 105.6 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPR79824.1 - 1.2e-05 25.5 0.0 3e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPR79824.1 - 2.9e-05 23.8 0.5 0.00091 18.9 0.4 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EPR79824.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zot PF05707.7 EPR79824.1 - 0.0018 17.7 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_2 PF07724.9 EPR79824.1 - 0.0029 17.5 0.0 0.0071 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF2075 PF09848.4 EPR79824.1 - 0.0053 15.7 0.0 0.013 14.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 EPR79824.1 - 0.012 15.2 0.0 0.32 10.5 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EPR79824.1 - 0.023 13.8 2.5 0.11 11.6 0.3 2.6 2 1 0 2 2 2 0 KaiC AAA_25 PF13481.1 EPR79824.1 - 0.023 14.1 0.0 0.1 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPR79824.1 - 0.026 14.5 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EPR79824.1 - 0.03 13.7 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EPR79824.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 EPR79824.1 - 0.039 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EPR79824.1 - 0.067 12.7 0.8 0.13 11.7 0.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPR79824.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPR79824.1 - 0.08 12.3 0.1 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein tRNA-synt_1c PF00749.16 EPR79825.1 - 4.1 5.9 8.0 0.29 9.7 0.5 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Cullin PF00888.17 EPR79826.1 - 2.4e-20 72.6 50.8 8.8e-17 60.8 7.1 2.6 1 1 0 2 2 2 2 Cullin family LRR_8 PF13855.1 EPR79827.1 - 7.3e-29 99.3 57.1 2.3e-08 33.6 5.5 9.2 5 4 4 10 10 10 7 Leucine rich repeat LRR_4 PF12799.2 EPR79827.1 - 7.9e-27 92.3 47.8 5e-09 35.5 6.4 12.0 6 4 6 12 12 12 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79827.1 - 2.1e-09 36.0 56.3 0.021 14.7 0.1 14.4 14 0 0 14 14 14 5 Leucine Rich Repeat LRR_7 PF13504.1 EPR79827.1 - 0.00035 20.2 28.4 0.77 10.2 0.1 10.7 12 1 0 12 12 12 3 Leucine rich repeat LRR_9 PF14580.1 EPR79827.1 - 0.0013 18.2 1.1 0.0013 18.2 0.8 3.5 4 0 0 4 4 4 1 Leucine-rich repeat LRR_6 PF13516.1 EPR79827.1 - 0.016 15.2 0.6 0.016 15.2 0.4 10.8 11 2 0 11 11 11 0 Leucine Rich repeat TPR_11 PF13414.1 EPR79828.1 - 1.5e-05 24.5 8.1 0.0096 15.5 0.6 2.7 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EPR79828.1 - 4.2e-05 23.1 2.0 0.075 12.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPR79828.1 - 6.9e-05 22.0 0.0 0.00025 20.1 0.0 2.0 1 0 0 1 1 1 1 SHNi-TPR TPR_12 PF13424.1 EPR79828.1 - 0.00046 20.0 6.2 0.36 10.8 0.1 3.4 1 1 1 3 3 3 1 Tetratricopeptide repeat DUF4363 PF14276.1 EPR79828.1 - 0.003 17.2 9.9 0.023 14.3 4.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4363) TPR_7 PF13176.1 EPR79828.1 - 0.0056 16.3 0.4 4.2 7.4 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Atg14 PF10186.4 EPR79828.1 - 0.0098 14.8 0.8 0.11 11.4 0.0 2.1 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 TPR_21 PF09976.4 EPR79828.1 - 0.012 15.5 0.4 7.4 6.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF835 PF05763.7 EPR79828.1 - 0.026 14.0 3.3 0.046 13.2 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF835) TPR_1 PF00515.23 EPR79828.1 - 0.034 13.7 3.3 5.4 6.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPR79828.1 - 0.061 14.0 0.0 6.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NPV_P10 PF05531.7 EPR79828.1 - 0.2 11.9 3.2 3.8 7.8 1.5 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TetR_C_8 PF14278.1 EPR79828.1 - 0.39 11.1 4.7 1.7 9.0 0.2 3.1 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Spectrin PF00435.16 EPR79828.1 - 0.59 10.4 6.9 0.25 11.6 1.3 2.6 2 1 1 3 3 3 0 Spectrin repeat GATA PF00320.22 EPR79829.1 - 1.9e-15 55.8 4.4 3.4e-15 55.0 3.1 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EPR79829.1 - 0.011 15.0 0.9 0.029 13.6 0.7 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding WWE PF02825.15 EPR79829.1 - 0.93 8.9 7.6 5.4 6.5 0.1 3.7 4 0 0 4 4 4 0 WWE domain Peptidase_M10 PF00413.19 EPR79830.1 - 0.00075 19.2 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin DUF955 PF06114.8 EPR79830.1 - 0.0015 18.2 0.1 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF955) Reprolysin_3 PF13582.1 EPR79830.1 - 0.0031 18.0 0.0 0.0062 17.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.14 EPR79830.1 - 0.0034 16.9 0.1 0.0063 16.1 0.1 1.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Reprolysin_2 PF13574.1 EPR79830.1 - 0.0061 16.6 1.2 0.037 14.0 0.9 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF2268 PF10026.4 EPR79830.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Reprolysin_4 PF13583.1 EPR79830.1 - 0.033 13.7 0.7 0.085 12.3 0.5 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EPR79830.1 - 0.091 12.6 0.2 0.2 11.5 0.1 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12 PsbQ PF05757.6 EPR79831.1 - 0.039 13.3 0.2 0.043 13.2 0.1 1.3 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) FA_desaturase PF00487.19 EPR79832.1 - 1.4e-29 103.3 11.5 1.4e-29 103.3 7.9 1.4 1 1 1 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.5 EPR79832.1 - 5.8e-07 28.6 0.4 1e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF2207 PF09972.4 EPR79832.1 - 3.9 5.9 8.9 0.21 10.1 0.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) LRR_8 PF13855.1 EPR79834.1 - 9.7e-18 63.6 35.3 4.1e-09 36.0 4.3 5.3 5 0 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EPR79834.1 - 1e-15 56.9 45.3 2.4e-06 26.9 0.6 8.0 3 3 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR79834.1 - 4.4e-06 25.9 40.2 0.069 13.2 0.0 10.2 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_7 PF13504.1 EPR79834.1 - 0.0061 16.5 26.6 13 6.5 0.0 9.9 11 0 0 11 11 11 2 Leucine rich repeat LRR_9 PF14580.1 EPR79834.1 - 0.031 13.8 14.0 0.2 11.1 2.7 3.7 1 1 1 3 3 3 0 Leucine-rich repeat DIM1 PF02966.11 EPR79836.1 - 9.5e-11 41.3 2.0 1.1e-10 41.1 1.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Ricin_B_lectin PF00652.17 EPR79837.1 - 0.00014 21.8 0.6 0.00034 20.6 0.3 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EPR79837.1 - 0.0017 18.6 0.4 0.0047 17.2 0.2 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 EPR79837.1 - 0.0042 16.4 0.1 0.0066 15.8 0.1 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family DEAD PF00270.24 EPR79839.1 - 3.1e-26 91.8 1.8 4.8e-26 91.2 0.9 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79839.1 - 4.8e-14 51.9 0.1 1.1e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79839.1 - 7.8e-06 25.8 1.1 7.8e-06 25.8 0.8 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EPR79839.1 - 0.00016 20.9 1.3 0.39 9.9 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Helicase_RecD PF05127.9 EPR79839.1 - 0.0014 18.3 0.1 0.0031 17.1 0.1 1.6 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.1 EPR79839.1 - 0.072 12.6 1.0 1.1 8.7 0.0 2.7 1 1 1 3 3 3 0 AAA domain SecA_DEAD PF07517.9 EPR79839.1 - 0.11 11.7 1.2 0.44 9.7 0.8 1.9 1 1 1 2 2 2 0 SecA DEAD-like domain zf-SNAP50_C PF12251.3 EPR79841.1 - 0.074 12.4 11.5 1.6 8.0 7.9 2.2 1 1 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Pkinase PF00069.20 EPR79842.1 - 3.9e-32 111.4 0.0 8.3e-32 110.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79842.1 - 2.2e-14 53.1 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79842.1 - 5e-05 22.3 0.0 7.7e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EPR79842.1 - 0.0047 16.5 0.5 0.009 15.6 0.3 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EPR79842.1 - 0.031 13.3 0.1 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR79842.1 - 0.041 13.6 0.0 0.85 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.12 EPR79843.1 - 2.3e-21 75.9 8.5 2.3e-21 75.9 5.9 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Myosin_tail_1 PF01576.14 EPR79843.1 - 0.034 11.8 8.7 0.039 11.6 6.0 1.1 1 0 0 1 1 1 0 Myosin tail zf-CCHH PF10283.4 EPR79843.1 - 0.051 13.4 0.9 0.093 12.5 0.6 1.4 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif GidB PF02527.10 EPR79843.1 - 0.22 10.6 3.2 1.4 8.0 0.2 2.3 1 1 0 2 2 2 0 rRNA small subunit methyltransferase G TSC22 PF01166.13 EPR79843.1 - 0.37 10.7 4.7 0.22 11.5 0.8 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF948 PF06103.6 EPR79843.1 - 0.53 10.1 2.8 0.5 10.2 0.9 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EPR79843.1 - 0.69 9.4 3.5 0.87 9.1 2.4 1.3 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EPR79843.1 - 4.1 7.2 9.9 0.05 13.4 1.4 1.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EPR79843.1 - 6 7.2 8.9 17 5.7 5.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) HTH_17 PF12728.2 EPR79844.1 - 0.00071 19.7 0.1 1.7 8.9 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_29 PF13551.1 EPR79844.1 - 0.003 17.7 0.0 0.0047 17.0 0.0 1.3 1 1 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EPR79844.1 - 0.0031 17.4 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EPR79844.1 - 0.012 15.6 0.4 0.12 12.3 0.1 2.4 3 0 0 3 3 3 0 Transposase HTH_32 PF13565.1 EPR79844.1 - 0.015 16.0 0.0 0.056 14.2 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.1 EPR79844.1 - 0.018 15.0 0.8 0.15 12.1 0.2 2.7 2 1 0 2 2 2 0 HTH-like domain HTH_6 PF01418.12 EPR79844.1 - 0.028 14.1 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_26 PF13443.1 EPR79844.1 - 0.071 13.3 0.1 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 EPR79844.1 - 0.1 12.2 0.0 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain GSIII_N PF12437.3 EPR79845.1 - 8.2e-66 220.4 0.0 1.4e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 EPR79845.1 - 3e-39 134.7 0.0 5.2e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain CPSase_L_D2 PF02786.12 EPR79846.1 - 1.2e-36 126.0 0.1 1e-21 77.2 0.0 2.5 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EPR79846.1 - 5.2e-17 61.9 0.0 3.5e-16 59.2 0.0 2.3 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Dala_Dala_lig_C PF07478.8 EPR79846.1 - 4.4e-09 36.0 3.5 1.8e-07 30.7 0.4 3.3 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPR79846.1 - 3.1e-08 32.7 0.0 5.8e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_carb_C PF02785.14 EPR79846.1 - 6.2e-07 29.3 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EPR79846.1 - 4.2e-06 26.6 0.0 8.4e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EPR79846.1 - 0.00094 18.5 0.0 1.3 8.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_N PF02844.10 EPR79846.1 - 0.041 14.3 0.0 0.2 12.1 0.0 2.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain NTF2 PF02136.15 EPR79847.1 - 3e-06 27.5 0.1 7.8e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain DUF2439 PF10382.4 EPR79847.1 - 0.013 15.6 2.3 0.013 15.6 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2439) Cbl_N PF02262.11 EPR79847.1 - 0.82 9.3 5.7 0.27 10.9 0.3 2.5 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 MCM PF00493.18 EPR79848.1 - 1.6e-129 431.5 1.5 1.6e-129 431.5 1.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EPR79848.1 - 7e-11 42.6 1.5 7e-11 42.6 1.1 3.0 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPR79848.1 - 6.3e-08 32.0 0.0 2.4e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPR79848.1 - 1.1e-07 31.7 0.1 5.2e-07 29.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPR79848.1 - 9.4e-06 25.2 0.0 3.9e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HypA PF01155.14 EPR79848.1 - 0.0035 17.0 0.3 0.0099 15.5 0.2 1.7 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family AAA_16 PF13191.1 EPR79848.1 - 0.03 14.3 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SWIB PF02201.13 EPR79849.1 - 1.9e-10 40.2 4.2 2e-10 40.2 0.5 2.6 2 0 0 2 2 2 1 SWIB/MDM2 domain tRNA-synt_2d PF01409.15 EPR79850.1 - 2.4e-90 302.0 0.1 3.8e-90 301.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPR79850.1 - 7e-05 22.4 2.0 0.00058 19.4 1.4 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) eIF-1a PF01176.14 EPR79851.1 - 7.5e-15 54.1 0.2 1e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Haemolytic PF01809.13 EPR79851.1 - 0.011 15.3 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 Haemolytic domain OppC_N PF12911.2 EPR79852.1 - 0.36 10.2 2.2 0.8 9.1 1.5 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C LRR_4 PF12799.2 EPR79854.1 - 3.3e-33 112.7 103.2 2e-09 36.8 4.4 10.8 5 4 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79854.1 - 5.8e-33 112.4 84.4 8.4e-09 35.0 2.1 10.0 4 3 8 13 13 13 12 Leucine rich repeat LRR_1 PF00560.28 EPR79854.1 - 3.1e-16 56.8 81.6 0.011 15.5 0.1 17.2 18 1 0 18 18 18 10 Leucine Rich Repeat LRR_7 PF13504.1 EPR79854.1 - 2.5e-10 38.8 46.7 0.66 10.4 0.0 15.3 16 0 0 16 16 16 5 Leucine rich repeat LRR_6 PF13516.1 EPR79854.1 - 0.0027 17.5 70.2 0.8 9.9 0.1 13.8 13 2 1 14 14 14 6 Leucine Rich repeat RNase_T PF00929.19 EPR79856.1 - 1.2e-18 67.9 2.5 2.3e-18 66.9 0.1 2.3 2 0 0 2 2 2 1 Exonuclease tRNA-synt_1 PF00133.17 EPR79857.1 - 4e-192 639.4 6.2 2.6e-191 636.7 4.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPR79857.1 - 2.7e-26 92.1 1.2 2.7e-26 92.1 0.8 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPR79857.1 - 4.5e-18 65.0 8.7 3e-10 39.3 0.1 5.7 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EPR79857.1 - 1.4e-15 57.1 0.1 1.9e-12 46.8 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 EPR79857.1 - 0.0008 18.3 0.1 0.012 14.4 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EPR79857.1 - 0.0015 17.6 1.8 1 8.4 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) Glyco_transf_15 PF01793.11 EPR79858.1 - 1.1e-117 392.7 18.1 1.3e-117 392.4 12.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GPP34 PF05719.6 EPR79860.1 - 2.7e-09 37.3 0.0 3.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Ribosomal_L19 PF01245.15 EPR79860.1 - 0.00068 19.4 0.9 0.0011 18.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 RLL PF10036.4 EPR79860.1 - 0.051 12.9 1.4 0.084 12.2 1.0 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Gag_p17 PF00540.13 EPR79860.1 - 0.086 12.6 0.5 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) DUF3467 PF11950.3 EPR79860.1 - 0.11 12.5 0.2 0.23 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) Frataxin_Cyay PF01491.11 EPR79861.1 - 2.5e-20 72.3 4.6 7.4e-20 70.7 3.2 1.6 1 1 0 1 1 1 1 Frataxin-like domain zf-RING_2 PF13639.1 EPR79862.1 - 1.7e-14 53.3 5.5 2.7e-14 52.7 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPR79862.1 - 6.6e-09 35.7 3.1 6.6e-09 35.7 2.2 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPR79862.1 - 5.7e-07 29.4 6.8 1e-06 28.6 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR79862.1 - 6.1e-07 29.0 4.7 1.1e-06 28.2 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPR79862.1 - 4.4e-06 26.2 7.0 7.5e-06 25.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR79862.1 - 2.3e-05 23.9 8.9 5.9e-05 22.6 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EPR79862.1 - 0.00033 20.6 0.8 0.00033 20.6 0.6 2.1 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-Apc11 PF12861.2 EPR79862.1 - 0.013 15.2 3.9 0.04 13.7 2.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 EPR79862.1 - 0.028 14.5 2.5 0.028 14.5 1.8 2.4 2 1 0 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.2 EPR79862.1 - 0.23 11.5 8.0 0.5 10.4 5.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 EPR79862.1 - 0.64 9.5 9.9 2.1 7.8 6.7 1.9 1 1 1 2 2 2 0 P-11 zinc finger FANCL_C PF11793.3 EPR79862.1 - 1.7 8.6 8.2 8 6.5 5.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EPR79862.1 - 3.1 7.4 9.0 6.2 6.4 6.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Kazal_1 PF00050.16 EPR79862.1 - 5.4 7.1 7.6 10 6.2 2.2 2.6 1 1 1 2 2 2 0 Kazal-type serine protease inhibitor domain Prok-RING_1 PF14446.1 EPR79862.1 - 5.7 6.7 8.5 3 7.6 1.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RB_B PF01857.15 EPR79863.1 - 0.75 9.2 10.9 0.32 10.4 0.3 2.9 2 1 1 3 3 3 0 Retinoblastoma-associated protein B domain WD40 PF00400.27 EPR79864.1 - 2e-34 116.1 6.1 6.7e-10 38.4 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPR79864.1 - 1e-24 86.2 0.3 2.3e-24 85.0 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 EPR79864.1 - 0.01 15.3 0.3 0.23 10.9 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MIP PF00230.15 EPR79865.1 - 4.7e-34 117.8 10.2 1.2e-21 77.2 1.9 2.0 2 0 0 2 2 2 2 Major intrinsic protein DUF2567 PF10821.3 EPR79865.1 - 0.013 15.0 0.5 0.029 13.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) Glycos_transf_1 PF00534.15 EPR79867.1 - 2.4e-18 66.1 0.0 1.2e-17 63.8 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPR79867.1 - 1e-05 25.7 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPR79867.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 UPF0184 PF03670.8 EPR79867.1 - 0.8 9.9 2.0 53 4.0 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) HPD PF05044.7 EPR79868.1 - 0.02 14.5 3.2 0.02 14.5 2.2 2.0 1 1 1 2 2 2 0 Homeo-prospero domain COX16 PF14138.1 EPR79868.1 - 0.23 11.6 1.3 0.5 10.5 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 PDGF_N PF04692.8 EPR79869.1 - 0.0084 16.5 0.6 0.02 15.3 0.4 1.7 1 0 0 1 1 1 1 Platelet-derived growth factor, N terminal region Dynein_light PF01221.13 EPR79871.1 - 0.08 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Dynein light chain type 1 PHA_synth_III_E PF09712.5 EPR79872.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Aa_trans PF01490.13 EPR79873.1 - 6.9e-29 100.5 49.7 9.1e-29 100.1 34.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trm112p PF03966.11 EPR79874.1 - 0.00021 21.5 2.9 0.0008 19.7 2.0 1.8 1 1 0 1 1 1 1 Trm112p-like protein DUF1451 PF07295.6 EPR79874.1 - 0.35 10.6 5.7 0.033 13.9 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) zf-HYPF PF07503.7 EPR79874.1 - 2.9 7.4 7.1 0.46 9.9 0.3 2.2 2 0 0 2 2 2 0 HypF finger TruB_N PF01509.13 EPR79875.1 - 1.1e-24 87.2 0.0 3.7e-21 75.8 0.0 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.7 EPR79875.1 - 1.3e-18 66.6 0.0 3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain PUA PF01472.15 EPR79875.1 - 2.3e-15 56.0 0.0 4.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 PUA domain Pinin_SDK_memA PF04696.8 EPR79876.1 - 0.00091 18.8 2.4 0.0016 18.0 1.7 1.3 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region HECT PF00632.20 EPR79877.1 - 0.14 11.3 4.3 0.18 10.9 3.0 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) WD40 PF00400.27 EPR79878.1 - 3.4e-41 137.6 10.0 1.5e-10 40.5 0.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPR79878.1 - 4.1e-05 23.3 0.9 0.081 12.6 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EPR79878.1 - 0.0001 20.6 0.1 0.0025 16.0 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3312) BBS2_Mid PF14783.1 EPR79878.1 - 0.00056 19.6 1.2 1.8 8.3 0.2 4.5 2 1 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EPR79878.1 - 0.0019 16.4 0.1 0.52 8.3 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Bacteriocin_II PF01721.13 EPR79878.1 - 0.008 15.6 1.2 0.023 14.1 0.8 1.8 1 0 0 1 1 1 1 Class II bacteriocin Nucleoporin_N PF08801.6 EPR79878.1 - 0.065 11.9 9.2 0.35 9.5 3.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Ribosomal_L14 PF00238.14 EPR79879.1 - 8.7e-33 112.6 0.5 9.7e-33 112.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Adaptin_N PF01602.15 EPR79880.1 - 2.4e-24 85.5 14.4 3e-23 81.9 10.0 2.6 1 1 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EPR79880.1 - 1.1e-17 63.9 2.7 2.1e-17 63.0 0.6 2.4 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EPR79880.1 - 1.6e-16 60.2 1.2 1.6e-16 60.2 0.9 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EPR79880.1 - 0.007 16.6 0.0 0.061 13.5 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats Ras PF00071.17 EPR79881.1 - 1.6e-51 173.9 0.1 1.8e-51 173.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR79881.1 - 2.6e-16 60.1 0.0 3.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPR79881.1 - 8.9e-13 47.8 0.0 1e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPR79881.1 - 4.5e-06 26.2 0.1 3.8e-05 23.1 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EPR79881.1 - 3.5e-05 23.3 0.0 7.2e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EPR79881.1 - 0.008 15.8 0.1 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EPR79881.1 - 0.008 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPR79881.1 - 0.0091 15.2 0.0 0.018 14.2 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPR79881.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EPR79881.1 - 0.066 12.4 0.9 1.1 8.5 0.6 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B PRK PF00485.13 EPR79881.1 - 0.096 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sec1 PF00995.18 EPR79882.1 - 1.2e-44 152.9 23.8 1.3e-29 103.2 11.5 2.9 1 1 1 2 2 2 2 Sec1 family Nucleoporin2 PF04096.9 EPR79883.1 - 5.1e-12 45.7 1.3 6.9e-12 45.3 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin autopeptidase TFIIA_gamma_C PF02751.9 EPR79884.1 - 2.4e-11 43.2 0.4 4.1e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EPR79884.1 - 8.2e-10 38.1 0.0 1.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain SBDS_C PF09377.5 EPR79884.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 SBDS protein C-terminal domain PUF PF00806.14 EPR79886.1 - 0.04 13.4 0.4 4.5 6.9 0.0 3.7 4 0 0 4 4 4 0 Pumilio-family RNA binding repeat AAA PF00004.24 EPR79887.1 - 2.4e-46 157.1 0.3 1e-44 151.9 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EPR79887.1 - 5.6e-06 26.3 0.2 2.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPR79887.1 - 2.3e-05 23.5 0.0 0.00052 19.1 0.0 2.4 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPR79887.1 - 0.00036 20.4 6.9 0.0066 16.3 0.0 3.8 2 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EPR79887.1 - 0.00047 19.8 0.0 0.0034 17.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPR79887.1 - 0.00082 19.5 0.4 0.32 11.1 0.0 3.6 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EPR79887.1 - 0.00098 19.2 0.1 0.34 11.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EPR79887.1 - 0.0042 17.0 0.0 0.039 13.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EPR79887.1 - 0.011 16.4 8.3 0.039 14.7 0.0 3.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EPR79887.1 - 0.047 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 EPR79887.1 - 0.05 12.7 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EPR79887.1 - 0.065 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EPR79887.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EPR79887.1 - 0.091 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EPR79887.1 - 0.19 11.1 0.0 17 4.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain DNA_primase_lrg PF04104.9 EPR79888.1 - 7.3e-44 149.9 7.0 7.3e-44 149.9 4.9 1.9 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit NAD_binding_1 PF00175.16 EPR79890.1 - 6.7e-20 71.6 0.1 1e-19 71.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPR79890.1 - 3.4e-10 39.9 0.0 7.9e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPR79890.1 - 2.8e-05 24.0 0.2 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Sel1 PF08238.7 EPR79891.1 - 2.1e-26 91.7 16.3 2.2e-05 24.9 1.2 6.9 6 1 1 7 7 7 5 Sel1 repeat TPR_11 PF13414.1 EPR79891.1 - 0.0069 16.0 9.3 0.0092 15.6 0.7 3.9 2 1 2 4 4 4 1 TPR repeat TPR_16 PF13432.1 EPR79891.1 - 0.077 13.7 1.8 1.3 9.7 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_S21 PF01165.15 EPR79891.1 - 0.26 10.7 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S21 CS PF04969.11 EPR79892.1 - 1.1e-08 35.5 1.9 1.6e-08 34.9 1.3 1.3 1 0 0 1 1 1 1 CS domain NTP_transferase PF00483.18 EPR79893.1 - 4.2e-42 144.1 0.0 5.8e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EPR79893.1 - 5.7e-14 50.8 6.9 9e-08 31.2 2.3 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPR79893.1 - 3.8e-10 40.0 0.0 5.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EPR79893.1 - 0.00016 21.1 3.1 0.00016 21.1 2.2 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EPR79893.1 - 0.0013 18.3 0.1 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.14 EPR79893.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Rib_5-P_isom_A PF06026.9 EPR79895.1 - 0.071 12.4 0.4 0.071 12.4 0.3 1.8 2 0 0 2 2 2 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) zf-RING_2 PF13639.1 EPR79896.1 - 1.7e-06 27.7 11.1 3.7e-06 26.6 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPR79896.1 - 0.00055 19.6 11.7 0.0011 18.6 8.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPR79896.1 - 0.0016 18.5 6.8 0.0055 16.7 4.8 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPR79896.1 - 0.0037 16.9 10.9 0.0069 16.0 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPR79896.1 - 0.036 14.0 15.8 0.072 13.1 10.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPR79896.1 - 0.1 12.4 5.7 0.22 11.4 4.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EPR79896.1 - 0.41 10.4 8.9 1.4 8.7 6.2 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EPR79896.1 - 0.45 10.2 13.7 1.9 8.2 8.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SWIRM PF04433.12 EPR79896.1 - 0.56 10.3 4.6 3.5 7.8 0.0 2.7 2 1 0 2 2 2 0 SWIRM domain LRR_4 PF12799.2 EPR79898.1 - 1.1e-23 82.3 71.8 5.7e-06 25.8 2.1 10.0 4 3 9 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR79898.1 - 2.1e-21 75.3 67.7 2e-06 27.4 2.1 8.8 3 2 6 10 10 10 8 Leucine rich repeat LRR_1 PF00560.28 EPR79898.1 - 3e-14 50.8 61.9 0.1 12.7 0.2 14.3 11 2 2 13 13 13 9 Leucine Rich Repeat LRR_7 PF13504.1 EPR79898.1 - 1.6e-06 27.3 35.0 1.4 9.3 0.2 11.6 11 1 0 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 EPR79898.1 - 3.2e-05 23.5 54.2 2.5 8.4 0.0 12.6 12 0 0 12 12 12 4 Leucine Rich repeat Proteasome PF00227.21 EPR79899.1 - 7.1e-40 136.3 2.0 8e-40 136.1 1.4 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_S21e PF01249.13 EPR79900.1 - 3.6e-12 46.0 0.0 3.8e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF4256 PF14066.1 EPR79901.1 - 0.1 12.0 0.6 0.16 11.4 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4256) TP6A_N PF04406.9 EPR79902.1 - 8.6e-07 28.5 0.8 1.9e-06 27.4 0.2 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase zf-RING_2 PF13639.1 EPR79904.1 - 2.3e-12 46.5 9.2 3.8e-12 45.8 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPR79904.1 - 6e-08 32.6 9.5 1.2e-07 31.7 6.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPR79904.1 - 1.7e-06 27.8 11.3 3.5e-06 26.9 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPR79904.1 - 3.2e-06 26.7 8.2 6.1e-06 25.8 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPR79904.1 - 5.1e-06 26.0 11.4 1.1e-05 24.9 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR79904.1 - 3.8e-05 23.2 11.5 5.8e-05 22.6 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EPR79904.1 - 0.0022 17.9 1.1 0.0038 17.2 0.8 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EPR79904.1 - 0.01 15.5 2.4 0.01 15.5 1.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger COX7C PF02935.11 EPR79904.1 - 0.034 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc zf-RING-like PF08746.6 EPR79904.1 - 0.04 13.9 7.6 0.074 13.0 5.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-Apc11 PF12861.2 EPR79904.1 - 0.043 13.6 8.1 0.22 11.3 5.6 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.1 EPR79904.1 - 0.049 13.7 3.5 0.085 13.0 2.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Baculo_RING PF05883.6 EPR79904.1 - 0.17 11.7 5.0 0.35 10.7 3.4 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.2 EPR79904.1 - 0.24 11.4 9.4 0.54 10.3 6.5 1.6 1 0 0 1 1 1 0 RING-variant domain SMC_N PF02463.14 EPR79905.1 - 3.2e-11 42.8 43.6 3.3e-11 42.8 1.0 3.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPR79905.1 - 5.7e-05 22.5 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EPR79905.1 - 0.00088 19.3 16.1 0.00088 19.3 11.1 5.0 1 1 1 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EPR79905.1 - 0.62 9.1 13.1 0.87 8.7 2.2 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein AAA_23 PF13476.1 EPR79905.1 - 7.1 6.9 147.4 1.3e+02 2.8 57.2 6.0 1 1 1 2 2 2 0 AAA domain Sulfate_transp PF00916.15 EPR79906.1 - 3.9e-12 45.7 5.6 3.9e-12 45.7 3.9 2.4 1 1 2 3 3 3 1 Sulfate transporter family Brevenin PF03032.10 EPR79907.1 - 0.14 12.0 0.2 0.14 12.0 0.1 2.8 3 0 0 3 3 3 0 Brevenin/esculentin/gaegurin/rugosin family FAD_binding_1 PF00667.15 EPR79908.1 - 2.2e-21 76.3 0.7 3.5e-21 75.6 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EPR79908.1 - 2.2e-06 28.1 0.1 2.9e-05 24.5 0.0 2.8 2 2 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPR79908.1 - 0.01 15.7 3.5 0.19 11.6 0.1 3.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain NAAA-beta PF15508.1 EPR79909.1 - 0.043 14.1 0.7 1.6 9.1 0.2 2.8 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Proteasome PF00227.21 EPR79910.1 - 2.1e-25 89.0 0.1 2.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Clathrin PF00637.15 EPR79910.1 - 0.027 14.0 0.4 0.073 12.6 0.2 1.6 1 0 0 1 1 1 0 Region in Clathrin and VPS Proteasome_A_N PF10584.4 EPR79910.1 - 0.035 13.4 0.0 0.081 12.2 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature AAA_12 PF13087.1 EPR79910.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EPR79911.1 - 8.5e-29 100.4 0.1 1.1e-28 100.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79911.1 - 6e-19 68.1 0.0 8.3e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ABC2_membrane_3 PF12698.2 EPR79912.1 - 0.0046 16.0 2.8 0.0057 15.7 1.9 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF2972 PF11186.3 EPR79912.1 - 0.022 14.6 1.8 0.026 14.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Turandot PF07240.6 EPR79912.1 - 0.066 12.7 0.4 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot DUF4125 PF13526.1 EPR79912.1 - 0.1 12.0 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) PTPA PF03095.10 EPR79915.1 - 1.4e-41 142.6 1.3 1.7e-39 135.8 1.0 2.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein Proteasome PF00227.21 EPR79916.1 - 4e-24 84.9 0.1 8.6e-24 83.8 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Ribosomal_L22 PF00237.14 EPR79917.1 - 1.5e-27 95.6 0.3 1.8e-27 95.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S13_N PF08069.7 EPR79917.1 - 0.081 12.7 0.2 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.24 EPR79918.1 - 4.9e-11 42.9 0.1 2.4e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPR79918.1 - 3.2e-07 30.3 1.0 3.2e-07 30.3 0.7 2.3 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPR79918.1 - 1.5e-06 27.9 0.1 4.9e-06 26.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPR79918.1 - 2.3e-06 27.8 0.2 6.9e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPR79918.1 - 0.00035 20.2 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPR79918.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EPR79918.1 - 0.00079 18.5 0.2 0.0033 16.4 0.1 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPR79918.1 - 0.002 18.9 0.5 0.01 16.6 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EPR79918.1 - 0.0025 17.7 0.3 0.007 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 EPR79918.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPR79918.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EPR79918.1 - 0.0093 16.0 0.1 0.081 12.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EPR79918.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EPR79918.1 - 0.014 15.2 9.1 0.58 9.9 0.1 3.4 2 2 1 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EPR79918.1 - 0.017 14.7 0.5 1.5 8.4 0.3 2.2 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EPR79918.1 - 0.032 14.5 5.7 0.35 11.1 4.0 2.4 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EPR79918.1 - 0.035 14.5 0.9 0.14 12.6 0.6 2.1 1 1 0 1 1 1 0 Miro-like protein NTPase_1 PF03266.10 EPR79918.1 - 0.039 13.6 1.6 0.89 9.2 0.1 2.6 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.1 EPR79918.1 - 0.041 13.4 8.8 0.14 11.6 6.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EPR79918.1 - 0.057 13.0 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EPR79918.1 - 0.06 12.9 2.6 0.12 11.9 1.8 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPR79918.1 - 0.32 11.1 3.6 0.37 10.9 0.5 2.5 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EPR79918.1 - 1.1 9.5 9.4 3.4 7.9 6.5 2.0 1 1 0 1 1 1 0 ABC transporter Beta-Casp PF10996.3 EPR79919.1 - 1.6e-32 112.0 0.0 4.2e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EPR79919.1 - 2.9e-16 59.7 0.1 7.8e-16 58.2 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPR79919.1 - 1.2e-11 44.5 0.1 2.6e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EPR79919.1 - 9.3e-11 41.3 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EPR79919.1 - 0.0054 16.4 0.1 0.024 14.3 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain CPSF73-100_C PF11718.3 EPR79919.1 - 0.015 14.6 1.2 0.036 13.4 0.8 1.7 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Abhydrolase_5 PF12695.2 EPR79920.1 - 2e-15 56.8 0.0 2.7e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPR79920.1 - 2.4e-10 40.6 0.0 4.4e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPR79920.1 - 0.0068 15.9 0.0 0.53 9.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 EPR79920.1 - 0.0071 16.0 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 EPR79921.1 - 9.3e-12 44.9 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPR79921.1 - 2.2e-05 24.4 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EPR79921.1 - 0.044 13.0 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Helicase_RecD PF05127.9 EPR79922.1 - 3e-52 176.7 0.0 4.2e-51 173.0 0.0 2.3 2 0 0 2 2 2 1 Helicase GNAT_acetyltr_2 PF13718.1 EPR79922.1 - 1.1e-49 168.4 0.0 9.6e-49 165.3 0.0 2.3 1 1 0 1 1 1 1 GNAT acetyltransferase 2 DUF1726 PF08351.6 EPR79922.1 - 7.6e-17 60.7 0.9 1.6e-15 56.5 0.1 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EPR79922.1 - 1.5e-15 57.0 0.5 5.6e-15 55.2 0.1 2.1 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EPR79922.1 - 5.4e-05 23.2 0.2 0.0003 20.8 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPR79922.1 - 0.0015 18.5 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Bromodomain PF00439.20 EPR79922.1 - 0.0062 16.4 1.2 0.018 14.9 0.1 2.4 2 0 0 2 2 2 1 Bromodomain AAA_30 PF13604.1 EPR79922.1 - 0.03 13.8 0.0 0.1 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain HD_assoc PF13286.1 EPR79922.1 - 0.057 13.7 0.0 21 5.4 0.0 3.0 3 0 0 3 3 3 0 Phosphohydrolase-associated domain AAA PF00004.24 EPR79923.1 - 2e-12 47.4 0.0 4.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EPR79923.1 - 2.4e-11 43.5 1.9 5.3e-09 35.9 0.2 2.9 1 1 2 3 3 3 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EPR79923.1 - 4.9e-08 33.1 0.4 0.0063 16.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 EPR79923.1 - 1.1e-06 28.5 0.1 2.8e-06 27.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPR79923.1 - 1.5e-06 28.2 0.0 2.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 EPR79923.1 - 3.6e-06 26.2 0.0 9.7e-06 24.7 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPR79923.1 - 3.7e-06 27.7 0.1 8.6e-06 26.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPR79923.1 - 6e-06 26.4 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 EPR79923.1 - 7.5e-06 25.7 0.6 0.0025 17.5 0.4 3.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EPR79923.1 - 7.7e-05 22.3 0.1 0.00014 21.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EPR79923.1 - 8.5e-05 21.4 3.4 0.011 14.4 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EPR79923.1 - 0.00018 21.5 0.1 0.00098 19.1 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 EPR79923.1 - 0.00022 21.5 5.4 0.0078 16.5 3.7 3.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPR79923.1 - 0.0004 19.8 0.0 0.0077 15.6 0.0 2.4 3 0 0 3 3 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPR79923.1 - 0.00044 19.4 0.1 0.0083 15.3 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPR79923.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPR79923.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EPR79923.1 - 0.0015 17.9 0.0 0.23 10.9 0.0 2.3 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_10 PF12846.2 EPR79923.1 - 0.0024 17.3 0.2 0.14 11.5 0.0 2.5 2 1 1 3 3 3 1 AAA-like domain AAA_11 PF13086.1 EPR79923.1 - 0.0043 16.6 0.1 0.0063 16.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPR79923.1 - 0.0049 16.5 1.3 0.011 15.3 0.8 1.9 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EPR79923.1 - 0.016 14.8 0.3 0.47 10.0 0.0 2.7 2 1 1 3 3 3 0 NACHT domain AAA_28 PF13521.1 EPR79923.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EPR79923.1 - 0.018 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rep_fac_C PF08542.6 EPR79923.1 - 0.018 14.9 0.6 0.16 11.9 0.1 2.7 2 1 0 2 2 2 0 Replication factor C C-terminal domain KaiC PF06745.8 EPR79923.1 - 0.019 14.0 0.1 0.094 11.8 0.1 2.0 1 1 0 1 1 1 0 KaiC ATP_bind_1 PF03029.12 EPR79923.1 - 0.022 14.3 0.6 3 7.3 0.0 2.9 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein PhoH PF02562.11 EPR79923.1 - 0.025 13.7 0.0 0.26 10.4 0.0 2.1 1 1 1 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 EPR79923.1 - 0.033 13.8 0.5 0.88 9.2 0.0 2.2 1 1 1 2 2 2 0 NTPase KTI12 PF08433.5 EPR79923.1 - 0.036 13.2 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SE PF00437.15 EPR79923.1 - 0.045 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EPR79923.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EPR79923.1 - 0.068 12.6 0.1 7.1 6.0 0.1 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase Pyrophosphatase PF00719.14 EPR79924.1 - 2.9e-45 153.5 0.2 3.8e-45 153.1 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase NifU_N PF01592.11 EPR79925.1 - 6.6e-50 168.2 0.0 7.5e-50 168.1 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DNA_pol_E_B PF04042.11 EPR79926.1 - 1.5e-17 63.5 1.6 2.1e-17 63.0 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PAH PF02671.16 EPR79926.1 - 0.048 13.2 2.1 8.2 6.1 0.0 3.3 3 0 0 3 3 3 0 Paired amphipathic helix repeat DUF2111 PF09884.4 EPR79926.1 - 0.11 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) WD40 PF00400.27 EPR79927.1 - 1.5e-21 75.3 10.4 9.8e-07 28.4 0.6 5.4 6 1 0 6 6 6 4 WD domain, G-beta repeat EcKinase PF02958.15 EPR79928.1 - 0.08 12.0 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pho88 PF10032.4 EPR79929.1 - 2.4e-29 101.9 1.0 2.8e-29 101.7 0.7 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF3816 PF12822.2 EPR79929.1 - 0.00073 19.4 0.6 0.00092 19.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) Bax1-I PF01027.15 EPR79929.1 - 0.013 15.1 1.1 0.31 10.5 0.1 2.0 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF1253 PF06862.7 EPR79929.1 - 0.017 13.5 5.2 0.021 13.2 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) DUF996 PF06195.8 EPR79929.1 - 0.14 12.1 2.1 2.7 7.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF2101 PF09874.4 EPR79929.1 - 1.1 8.7 5.8 0.31 10.4 1.4 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2101) Post_transc_reg PF13797.1 EPR79930.1 - 0.012 15.2 7.0 0.89 9.1 0.5 3.3 1 1 2 3 3 3 0 Post-transcriptional regulator FolB PF02152.13 EPR79930.1 - 0.2 11.8 3.0 4.1 7.5 0.1 2.2 1 1 1 2 2 2 0 Dihydroneopterin aldolase Plasmid_killer PF05015.8 EPR79930.1 - 1.6 8.9 6.0 10 6.3 0.3 2.5 1 1 0 2 2 2 0 Plasmid maintenance system killer protein HLH PF00010.21 EPR79930.1 - 2.9 7.6 11.3 0.39 10.4 3.4 2.7 2 2 0 2 2 2 0 Helix-loop-helix DNA-binding domain LMSTEN PF07988.7 EPR79930.1 - 4.8 6.5 0.0 4.8 6.5 0.0 3.0 3 0 0 3 3 3 0 LMSTEN motif ParA PF10609.4 EPR79931.1 - 2.5e-26 91.3 0.0 6.7e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPR79931.1 - 5.4e-23 81.4 0.1 9.7e-23 80.5 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPR79931.1 - 3.1e-11 43.4 0.0 5.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR79931.1 - 2.6e-05 24.5 1.1 0.0002 21.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPR79931.1 - 0.00024 21.9 0.2 0.00065 20.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EPR79931.1 - 0.00049 19.2 6.9 0.15 11.0 0.7 3.3 2 1 1 3 3 3 2 Anion-transporting ATPase MipZ PF09140.6 EPR79931.1 - 0.0022 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ABC_tran PF00005.22 EPR79931.1 - 0.0044 17.3 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EPR79931.1 - 0.0071 15.5 0.1 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF677 PF05055.7 EPR79931.1 - 0.014 14.0 0.4 0.03 12.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Zeta_toxin PF06414.7 EPR79931.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Fer4_NifH PF00142.13 EPR79931.1 - 0.017 14.3 0.3 0.19 10.9 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF87 PF01935.12 EPR79931.1 - 0.046 13.5 0.6 0.14 11.9 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF87 Pkinase PF00069.20 EPR79932.1 - 7.1e-35 120.4 0.3 7.1e-35 120.4 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79932.1 - 1.2e-22 80.2 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPR79932.1 - 0.00036 19.6 0.1 0.00069 18.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPR79932.1 - 0.0014 18.4 1.4 0.0022 17.7 0.9 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPR79932.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DNA_ligase_A_N PF04675.9 EPR79932.1 - 0.018 14.8 0.9 0.094 12.5 0.0 2.4 3 0 0 3 3 3 0 DNA ligase N terminus DUF1598 PF07643.6 EPR79932.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) TAFII55_N PF04658.8 EPR79934.1 - 2.7e-24 85.4 6.4 2.7e-24 85.4 4.4 2.8 2 1 0 2 2 2 1 TAFII55 protein conserved region SRA1 PF07304.6 EPR79934.1 - 0.18 11.5 2.8 3 7.5 0.0 2.8 1 1 1 2 2 2 0 Steroid receptor RNA activator (SRA1) FlaC_arch PF05377.6 EPR79934.1 - 3.5 7.5 15.4 0.47 10.3 0.6 3.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec23_trunk PF04811.10 EPR79935.1 - 1e-17 64.3 0.5 2.7e-16 59.6 0.3 2.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 EPR79935.1 - 2.8e-14 52.3 2.1 4.9e-14 51.5 1.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EPR79935.1 - 4.5e-13 49.5 0.0 7.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 EPR79935.1 - 1.6e-06 27.4 0.5 4.2e-06 26.1 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EPR79935.1 - 0.002 17.7 0.0 0.002 17.7 0.0 2.5 3 0 0 3 3 3 1 Gelsolin repeat Urb2 PF10441.4 EPR79936.1 - 0.0024 17.5 0.4 0.27 10.8 0.0 3.1 3 0 0 3 3 3 1 Urb2/Npa2 family RIX1 PF08167.7 EPR79936.1 - 0.024 14.3 0.0 5.7 6.5 0.0 3.3 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis IBN_N PF03810.14 EPR79936.1 - 0.033 14.0 0.1 0.22 11.4 0.0 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain Peptidase_M24 PF00557.19 EPR79937.1 - 8.1e-38 130.0 0.1 9.9e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 MOZ_SAS PF01853.13 EPR79938.1 - 1.9e-79 265.3 4.2 3.9e-79 264.2 2.9 1.5 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EPR79938.1 - 8e-14 51.0 0.6 8e-14 51.0 0.4 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EPR79938.1 - 0.039 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-H2C2_5 PF13909.1 EPR79938.1 - 0.56 10.5 5.4 1.5 9.2 3.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Pkinase PF00069.20 EPR79939.1 - 3.6e-18 65.6 0.8 5e-18 65.1 0.4 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79939.1 - 7.1e-05 21.9 0.4 9.2e-05 21.6 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CHY PF05495.7 EPR79939.1 - 0.0038 17.3 5.7 0.0038 17.3 4.0 1.8 2 0 0 2 2 2 1 CHY zinc finger Rpr2 PF04032.11 EPR79939.1 - 0.0075 16.1 6.6 0.018 14.9 4.6 1.7 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-HIT PF04438.11 EPR79939.1 - 3.9 7.2 10.6 4.1 7.1 1.1 2.7 2 0 0 2 2 2 0 HIT zinc finger Pkinase PF00069.20 EPR79940.1 - 1.5e-43 148.8 0.0 2e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79940.1 - 1e-21 77.1 0.0 1.5e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR79940.1 - 5.2e-06 25.6 0.0 8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPR79940.1 - 0.031 14.0 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.23 EPR79941.1 - 5.3e-122 407.2 0.4 5.3e-122 407.2 0.3 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPR79941.1 - 6.1e-46 155.9 2.8 9.8e-46 155.2 2.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EPR79941.1 - 7.1e-27 93.4 0.0 2e-26 92.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EPR79941.1 - 2.4e-21 75.3 0.1 5.8e-21 74.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPR79941.1 - 1.4e-17 63.1 0.1 3.8e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EPR79941.1 - 8.6e-16 57.9 1.5 2.3e-15 56.5 1.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.12 EPR79941.1 - 7.6e-07 29.0 0.9 2e-06 27.6 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Phage_Coat_Gp8 PF05371.7 EPR79942.1 - 0.25 10.9 1.0 0.58 9.7 0.5 1.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Nol1_Nop2_Fmu PF01189.12 EPR79944.1 - 2.8e-75 253.3 0.0 3.2e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EPR79944.1 - 7.9e-07 28.7 0.3 1.2e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPR79944.1 - 6.4e-06 26.2 0.0 1.2e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EPR79944.1 - 1.4e-05 25.0 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPR79944.1 - 0.021 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 EPR79944.1 - 0.043 13.3 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF4342 PF14242.1 EPR79944.1 - 0.096 12.4 0.5 16 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Adaptin_N PF01602.15 EPR79945.1 - 3.7e-25 88.2 21.8 6.5e-25 87.4 15.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPR79945.1 - 1.4e-05 25.3 0.0 0.12 12.6 0.0 3.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EPR79945.1 - 0.058 13.4 0.0 54 4.2 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat DUF4327 PF14217.1 EPR79946.1 - 0.08 12.7 0.7 0.27 11.0 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4327) UDPGP PF01704.13 EPR79947.1 - 1.1e-149 498.5 1.7 1.4e-149 498.2 1.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TPT PF03151.11 EPR79948.1 - 4.6e-08 32.8 10.7 4.6e-08 32.8 7.4 3.1 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EPR79948.1 - 6.7 5.5 32.6 31 3.3 22.6 2.1 1 1 0 1 1 1 0 UAA transporter family dCMP_cyt_deam_1 PF00383.17 EPR79949.1 - 4.7e-05 22.9 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region ATP-synt_F PF01990.12 EPR79950.1 - 2.3e-18 66.3 1.1 2.5e-18 66.2 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit ECR1_N PF14382.1 EPR79951.1 - 6.5e-09 34.9 0.5 1.2e-08 34.0 0.4 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EPR79951.1 - 0.0049 16.7 0.4 0.58 10.1 0.1 2.4 2 0 0 2 2 2 2 Exosome component EXOSC1/CSL4 S1 PF00575.18 EPR79951.1 - 0.023 14.7 2.1 0.66 10.1 0.0 2.8 3 0 0 3 3 3 0 S1 RNA binding domain HAS-barrel PF09378.5 EPR79951.1 - 0.23 11.4 4.9 2.8 7.9 0.3 3.0 2 1 0 2 2 2 0 HAS barrel domain Ribosomal_S9 PF00380.14 EPR79952.1 - 1.8e-22 79.8 0.1 2.1e-22 79.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.13 EPR79953.1 - 3.4e-40 137.4 2.3 4e-40 137.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e DUF4164 PF13747.1 EPR79953.1 - 0.09 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PIP5K PF01504.13 EPR79954.1 - 3.5e-61 206.4 9.1 3.5e-61 206.4 6.3 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIIS_C PF01096.13 EPR79955.1 - 8.7e-06 25.2 8.5 9.6e-06 25.1 0.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPR79955.1 - 1.2e-05 24.8 5.4 1.2e-05 24.8 3.8 3.2 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EPR79955.1 - 0.00097 19.3 6.2 0.18 12.1 0.4 2.3 1 1 1 2 2 2 2 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EPR79955.1 - 0.0094 15.7 0.0 0.0094 15.7 0.0 2.5 2 1 0 2 2 2 1 Transposase zinc-ribbon domain FYVE PF01363.16 EPR79955.1 - 0.014 15.2 4.6 1.6 8.6 0.1 2.2 1 1 1 2 2 2 0 FYVE zinc finger RPA_interact_C PF14768.1 EPR79955.1 - 0.025 14.9 5.2 2.3 8.6 0.7 3.0 3 0 0 3 3 3 0 Replication protein A interacting C-terminal DUF4182 PF13790.1 EPR79955.1 - 0.041 13.6 2.0 0.041 13.6 1.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4182) Nudix_N_2 PF14803.1 EPR79955.1 - 0.084 12.5 0.6 0.084 12.5 0.4 3.0 3 0 0 3 3 3 0 Nudix N-terminal zf-CHY PF05495.7 EPR79955.1 - 0.14 12.3 9.6 1.3e+02 2.8 6.6 2.4 1 1 0 1 1 1 0 CHY zinc finger Big_3_3 PF13750.1 EPR79955.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) GFA PF04828.9 EPR79955.1 - 0.24 11.3 3.7 3.4 7.6 0.0 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme C1_4 PF07975.7 EPR79955.1 - 0.27 11.2 9.3 1.1 9.2 1.1 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain zf-UBP PF02148.14 EPR79955.1 - 0.65 10.1 5.6 2.6 8.2 1.3 2.3 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Elf1 PF05129.8 EPR79955.1 - 0.89 9.2 6.8 0.61 9.8 0.5 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.1 EPR79955.1 - 1.2 9.4 6.9 0.75 10.1 0.7 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Tnp_zf-ribbon_2 PF13842.1 EPR79955.1 - 1.2 9.6 7.1 5.6 7.4 0.1 3.2 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon Churchill PF06573.6 EPR79955.1 - 1.6 8.7 6.5 3.3 7.7 0.4 2.3 1 1 1 2 2 2 0 Churchill protein DZR PF12773.2 EPR79955.1 - 2.5 7.9 9.8 1.3 8.8 0.5 2.9 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.8 EPR79955.1 - 2.7 7.5 7.9 0.22 11.0 1.1 2.5 2 1 0 2 2 2 0 InsA N-terminal domain IBR PF01485.16 EPR79955.1 - 2.9 7.8 9.8 4.8 7.1 0.9 2.8 2 1 0 2 2 2 0 IBR domain zf-C4pol PF14260.1 EPR79955.1 - 3.8 7.5 9.2 13 5.8 0.4 3.0 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta UPF0547 PF10571.4 EPR79955.1 - 4 7.2 0.0 4 7.2 0.0 3.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF2296 PF10058.4 EPR79955.1 - 6 6.6 15.3 14 5.4 0.1 3.7 2 2 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) DUF3795 PF12675.2 EPR79955.1 - 6.2 7.0 9.0 8.8 6.5 1.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3795) HNH PF01844.18 EPR79955.1 - 9 6.2 12.7 29 4.6 0.7 3.7 2 1 1 3 3 3 0 HNH endonuclease zf-3CxxC PF13695.1 EPR79955.1 - 9.7 6.4 13.6 0.27 11.4 2.3 2.5 2 1 1 3 3 3 0 Zinc-binding domain Fip1 PF05182.8 EPR79956.1 - 1.4e-24 85.0 2.1 1.4e-24 85.0 1.4 1.8 2 0 0 2 2 2 1 Fip1 motif V-ATPase_G PF03179.10 EPR79957.1 - 4e-08 33.5 14.3 4.3e-08 33.4 9.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF4056 PF13265.1 EPR79957.1 - 0.017 14.1 0.2 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) HrpJ PF07201.6 EPR79957.1 - 0.037 14.0 7.4 0.066 13.2 5.2 1.6 1 1 0 1 1 1 0 HrpJ-like domain Troponin PF00992.15 EPR79957.1 - 0.32 11.0 13.7 0.14 12.2 7.8 1.7 1 1 0 1 1 1 0 Troponin Cep57_CLD PF14073.1 EPR79957.1 - 0.36 10.6 14.5 0.42 10.4 10.1 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 HTH_WhiA PF02650.9 EPR79957.1 - 0.52 10.7 4.7 0.4 11.0 1.8 1.7 1 1 1 2 2 2 0 WhiA C-terminal HTH domain EURL PF06937.6 EPR79957.1 - 1.1 8.6 7.3 1.3 8.3 5.0 1.1 1 0 0 1 1 1 0 EURL protein APG6 PF04111.7 EPR79957.1 - 4.5 6.2 12.9 6 5.8 8.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FlgN PF05130.7 EPR79957.1 - 9.6 6.4 15.0 25 5.1 5.0 2.2 1 1 1 2 2 2 0 FlgN protein FtsJ PF01728.14 EPR79958.1 - 1.8e-51 174.6 0.0 3.5e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ste50p-SAM PF09235.5 EPR79958.1 - 0.026 14.5 4.5 0.043 13.8 0.7 2.9 3 0 0 3 3 3 0 Ste50p, sterile alpha motif WD40 PF00400.27 EPR79959.1 - 1.9e-08 33.8 0.0 0.085 12.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPR79959.1 - 0.027 14.2 6.1 0.29 10.9 0.2 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 EPR79960.1 - 3.9e-31 108.1 2.1 3.9e-31 108.1 1.4 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79960.1 - 1.5e-17 63.5 0.1 2.7e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.3 EPR79960.1 - 0.11 11.8 4.3 0.18 11.2 0.1 2.8 2 1 1 3 3 3 0 Protein-kinase domain of FAM69 Ribosomal_L7Ae PF01248.21 EPR79961.1 - 0.88 9.1 4.1 0.26 10.8 0.5 1.8 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.20 EPR79962.1 - 9.9e-33 113.3 1.4 9.9e-33 113.3 1.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR79962.1 - 2.2e-17 62.9 0.0 4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_B_3 PF08408.5 EPR79963.1 - 0.05 13.4 6.9 0.14 12.0 4.8 1.7 1 1 0 1 1 1 0 DNA polymerase family B viral insert DUF2772 PF10970.3 EPR79963.1 - 0.065 13.2 0.6 0.095 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) NUMOD4 PF07463.6 EPR79963.1 - 0.085 12.7 0.7 0.16 11.8 0.5 1.6 1 1 0 1 1 1 0 NUMOD4 motif Ribosomal_L14e PF01929.12 EPR79963.1 - 0.12 12.7 0.4 0.28 11.5 0.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L14 UCH PF00443.24 EPR79964.1 - 2.1e-44 151.6 28.1 1.6e-24 86.4 10.4 3.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPR79964.1 - 8.3e-12 45.1 5.7 2.2e-08 33.9 4.0 4.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CHDCT2 PF08074.6 EPR79964.1 - 0.0087 15.8 0.8 0.019 14.6 0.5 1.5 1 0 0 1 1 1 1 CHDCT2 (NUC038) domain PGK PF00162.14 EPR79965.1 - 2e-84 283.3 0.0 2.4e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase G_glu_transpept PF01019.16 EPR79966.1 - 1e-135 453.1 0.0 1.2e-135 452.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ricin_B_lectin PF00652.17 EPR79967.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EPR79967.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like IncA PF04156.9 EPR79967.1 - 1.3 8.5 8.2 2 7.9 5.7 1.3 1 0 0 1 1 1 0 IncA protein DUF1192 PF06698.6 EPR79967.1 - 2.2 8.1 5.8 0.44 10.3 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) IFP_35_N PF07334.8 EPR79967.1 - 3.2 7.7 9.2 27 4.8 0.4 3.1 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SNF2_N PF00176.18 EPR79968.1 - 2.2e-71 240.1 7.8 2.2e-71 240.1 5.4 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EPR79968.1 - 2.7e-29 102.0 12.8 2.7e-29 102.0 8.9 4.5 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EPR79968.1 - 3.4e-15 55.6 0.5 2.9e-14 52.6 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPR79968.1 - 1.2e-07 31.4 0.7 5.9e-07 29.1 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase BRCT PF00533.21 EPR79969.1 - 0.21 11.7 3.0 0.11 12.6 0.3 1.9 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Arf PF00025.16 EPR79970.1 - 1.9e-36 124.8 0.1 2.6e-36 124.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPR79970.1 - 1.6e-10 40.9 0.2 2.5e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EPR79970.1 - 3.4e-10 39.5 0.0 4.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPR79970.1 - 6.1e-10 38.3 0.1 2.5e-05 23.1 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EPR79970.1 - 1.2e-09 38.6 0.0 2.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EPR79970.1 - 3.9e-09 35.9 0.0 4.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPR79970.1 - 1.1e-08 34.4 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPR79970.1 - 5.5e-07 29.1 0.4 0.0001 21.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 EPR79970.1 - 0.0023 17.4 0.3 0.75 9.2 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EPR79970.1 - 0.014 14.6 1.7 0.11 11.7 1.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 EPR79970.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EPR79970.1 - 0.035 13.6 0.0 0.063 12.7 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EPR79970.1 - 0.11 12.0 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 EPR79970.1 - 0.12 11.6 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase PROCN PF08083.6 EPR79973.1 - 1.6e-45 155.3 21.3 1.7e-25 89.3 5.8 3.3 3 0 0 3 3 3 3 PROCN (NUC071) domain RNase_HII PF01351.13 EPR79974.1 - 2.2e-32 112.3 2.1 2.4e-30 105.6 1.5 2.2 1 1 0 1 1 1 1 Ribonuclease HII AAA_31 PF13614.1 EPR79974.1 - 0.087 12.7 0.2 0.24 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Myb_DNA-bind_6 PF13921.1 EPR79975.1 - 6.3e-22 77.4 5.9 1.2e-13 50.8 0.9 3.3 3 2 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPR79975.1 - 3.4e-21 75.0 5.5 4.7e-12 45.7 0.6 3.2 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EPR79975.1 - 0.00012 22.1 19.1 0.0003 20.8 0.4 4.4 3 1 1 4 4 4 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EPR79975.1 - 0.01 15.6 2.6 1.1 9.1 0.4 3.7 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.1 EPR79975.1 - 0.48 10.3 5.0 1.9 8.4 0.3 3.7 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EPR79975.1 - 0.61 10.7 0.1 0.61 10.7 0.1 4.2 3 1 2 5 5 5 0 Myb/SANT-like DNA-binding domain CDP-OH_P_transf PF01066.16 EPR79976.1 - 2.2e-17 63.1 5.1 2.2e-17 63.1 3.5 3.6 1 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Homeobox_KN PF05920.6 EPR79977.1 - 7e-18 64.0 0.8 1.4e-17 63.0 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPR79977.1 - 9.6e-08 31.5 2.8 9.6e-08 31.5 1.9 2.4 3 0 0 3 3 3 1 Homeobox domain DDE_Tnp_1_4 PF13701.1 EPR79977.1 - 0.0068 14.6 0.3 0.011 13.9 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain group 1 Imm42 PF15601.1 EPR79977.1 - 0.07 12.5 1.0 0.13 11.6 0.7 1.5 1 0 0 1 1 1 0 Immunity protein 42 eIF2A PF08662.6 EPR79978.1 - 1.2e-26 93.5 2.1 1.2e-26 93.5 1.5 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1307 PF06998.6 EPR79978.1 - 0.0023 17.9 4.6 0.0023 17.9 3.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1307) ProRS-C_1 PF09180.6 EPR79979.1 - 7.2e-23 80.2 0.5 2.1e-22 78.7 0.3 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EPR79979.1 - 5e-22 78.2 0.3 9.9e-22 77.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPR79979.1 - 5.5e-16 58.2 0.8 9.5e-16 57.5 0.1 1.8 2 0 0 2 2 2 1 Anticodon binding domain TFIID_30kDa PF03540.8 EPR79980.1 - 2.7e-17 62.3 0.0 5.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Syntaxin_2 PF14523.1 EPR79980.1 - 0.071 13.1 0.2 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 Syntaxin-like protein DUF1836 PF08876.6 EPR79981.1 - 2.3 8.0 6.9 0.7 9.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) HSP70 PF00012.15 EPR79983.1 - 3.5e-173 576.7 5.3 1.8e-91 306.9 0.1 2.5 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EPR79983.1 - 3.9e-10 38.8 0.6 5.3e-06 25.2 0.0 4.1 4 1 0 4 4 4 3 MreB/Mbl protein Hydantoinase_A PF01968.13 EPR79983.1 - 0.011 14.8 0.2 0.25 10.3 0.0 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EPR79983.1 - 0.019 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain P-II PF00543.17 EPR79983.1 - 0.034 14.6 1.5 0.091 13.2 1.1 1.7 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II DltD_M PF04918.7 EPR79983.1 - 0.043 13.9 1.8 0.12 12.5 1.3 1.7 1 0 0 1 1 1 0 DltD central region TPP_enzyme_N PF02776.13 EPR79983.1 - 0.067 12.6 0.1 0.98 8.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MRC1 PF09444.5 EPR79983.1 - 9.5 6.5 12.2 1.7 8.9 5.7 1.8 2 0 0 2 2 2 0 MRC1-like domain Topoisom_bac PF01131.15 EPR79984.1 - 7e-82 275.3 2.7 3.4e-81 273.1 0.4 2.2 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 EPR79984.1 - 5.4e-16 58.3 1.0 2.1e-15 56.5 0.1 2.5 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.1 EPR79984.1 - 0.02 14.8 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Toprim domain 7TMR-DISM_7TM PF07695.6 EPR79985.1 - 0.65 9.6 2.7 1.2 8.8 1.9 1.4 1 0 0 1 1 1 0 7TM diverse intracellular signalling Rad21_Rec8_N PF04825.8 EPR79986.1 - 4.8e-08 32.9 2.9 4.8e-08 32.9 2.0 2.3 2 1 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPR79986.1 - 0.0036 16.4 0.0 0.009 15.1 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Pox_MCEL PF03291.11 EPR79987.1 - 4e-42 144.2 43.6 5.8e-38 130.5 12.5 3.4 2 2 0 3 3 3 2 mRNA capping enzyme Methyltransf_31 PF13847.1 EPR79987.1 - 1.5e-18 66.7 1.5 4.2e-18 65.3 1.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPR79987.1 - 1.5e-10 41.3 0.1 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPR79987.1 - 2.3e-10 40.8 0.0 5.9e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPR79987.1 - 2.7e-10 40.5 0.0 2.7e-10 40.5 0.0 3.4 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR79987.1 - 3.1e-10 40.6 0.0 6.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPR79987.1 - 8e-09 35.4 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPR79987.1 - 7.5e-07 28.4 0.6 1.6e-06 27.4 0.1 1.8 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EPR79987.1 - 3.6e-06 26.4 0.0 7.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EPR79987.1 - 5.4e-05 22.6 0.0 9.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EPR79987.1 - 5.8e-05 23.0 0.0 9.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPR79987.1 - 0.0012 18.4 5.2 0.0038 16.9 3.6 2.2 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EPR79987.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) FmrO PF07091.6 EPR79987.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 EPR79987.1 - 0.01 15.1 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.14 EPR79987.1 - 0.04 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Daxx PF03344.10 EPR79987.1 - 0.34 9.3 37.2 0.53 8.7 25.8 1.2 1 0 0 1 1 1 0 Daxx Family Ribosomal_S7e PF01251.13 EPR79988.1 - 0.016 14.7 1.7 0.017 14.6 0.3 1.5 1 1 0 1 1 1 0 Ribosomal protein S7e DUF4602 PF15375.1 EPR79988.1 - 0.035 14.1 13.8 0.039 14.0 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Rep_fac-A_C PF08646.5 EPR79989.1 - 5.7e-44 149.3 5.0 5.7e-44 149.3 3.4 4.6 4 1 1 5 5 5 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EPR79989.1 - 2.6e-18 65.6 1.3 1.9e-09 37.2 0.0 4.5 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 EPR79989.1 - 5.8e-11 42.0 0.3 2.2e-10 40.2 0.2 2.0 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF4539 PF15072.1 EPR79989.1 - 0.0037 16.9 0.6 2.1 8.0 0.0 3.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4539) BRCA-2_OB1 PF09103.5 EPR79989.1 - 0.012 15.3 0.1 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 TPP1 PF10341.4 EPR79989.1 - 0.02 14.8 0.5 0.13 12.2 0.1 2.5 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD HECT_2 PF09814.4 EPR79990.1 - 1.3e-10 40.5 0.5 1.3e-10 40.5 0.3 1.6 2 0 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding MS_channel PF00924.13 EPR79991.1 - 5.2e-19 68.3 1.2 1.3e-18 67.1 0.9 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel NapE PF06796.6 EPR79991.1 - 1.4 8.2 9.3 0.051 12.8 1.5 2.4 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE FAM176 PF14851.1 EPR79991.1 - 3.5 7.2 11.8 8.2 6.0 8.2 1.6 1 0 0 1 1 1 0 FAM176 family DEAD PF00270.24 EPR79992.1 - 3.5e-46 156.7 0.2 7.2e-45 152.5 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR79992.1 - 1.1e-26 92.4 0.7 9.1e-26 89.5 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR79992.1 - 2.6e-05 24.1 1.9 3.2e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPR79992.1 - 0.004 16.2 0.6 0.011 14.8 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit U6-snRNA_bdg PF10596.4 EPR79992.1 - 0.023 14.0 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 AAA_22 PF13401.1 EPR79992.1 - 0.6 10.2 5.2 2.2 8.4 2.4 2.6 2 1 0 2 2 2 0 AAA domain RINGv PF12906.2 EPR79993.1 - 1.1e-11 44.5 5.9 1.8e-11 43.8 4.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EPR79993.1 - 0.4 10.5 6.1 0.91 9.4 4.2 1.6 1 1 0 1 1 1 0 Ring finger domain NPCC PF08058.6 EPR79993.1 - 2 8.2 7.9 3.2 7.5 5.5 1.4 1 0 0 1 1 1 0 Nuclear pore complex component rve_2 PF13333.1 EPR79994.1 - 0.4 10.7 10.0 0.12 12.4 3.0 3.2 3 0 0 3 3 3 0 Integrase core domain Pro_isomerase PF00160.16 EPR79997.1 - 8.4e-47 159.2 0.4 9.4e-47 159.0 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phytoreo_P8 PF07124.6 EPR79999.1 - 0.019 13.6 0.2 0.027 13.1 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 DUF3567 PF12091.3 EPR80001.1 - 0.0054 16.6 0.7 1.1 9.2 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3567) PGI PF00342.14 EPR80002.1 - 2.8e-126 421.7 2.7 3.8e-126 421.3 1.9 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase DnaB_2 PF07261.6 EPR80003.1 - 0.02 14.4 2.1 6.3 6.4 0.2 3.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment RAMPs PF03787.10 EPR80003.1 - 4.1 7.1 7.4 8.1 6.2 5.1 1.8 1 1 0 1 1 1 0 RAMP superfamily Glyco_transf_22 PF03901.12 EPR80004.1 - 4.9e-51 174.0 38.2 5.9e-51 173.7 26.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FAM72 PF14976.1 EPR80005.1 - 2.2e-05 24.3 4.2 2.2e-05 24.3 2.9 2.1 1 1 1 2 2 2 1 FAM72 protein Endonuclease_7 PF02945.10 EPR80005.1 - 0.0016 18.0 0.7 0.0016 18.0 0.5 1.7 2 0 0 2 2 2 1 Recombination endonuclease VII PHF5 PF03660.9 EPR80005.1 - 0.015 15.3 1.8 0.029 14.4 1.3 1.5 1 0 0 1 1 1 0 PHF5-like protein Yippee-Mis18 PF03226.9 EPR80005.1 - 0.95 9.5 17.3 5.4e+03 -2.5 12.6 2.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cpn60_TCP1 PF00118.19 EPR80006.1 - 1.4e-100 337.2 20.3 1.6e-100 337.0 14.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ADK PF00406.17 EPR80006.1 - 0.076 12.8 0.7 11 5.9 0.0 2.7 2 1 0 2 2 2 0 Adenylate kinase Pkinase PF00069.20 EPR80007.1 - 1e-45 155.9 1.2 1e-45 155.9 0.8 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR80007.1 - 3e-22 78.9 0.2 7.2e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPR80007.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family eIF-5_eIF-2B PF01873.12 EPR80009.1 - 5.8e-30 103.5 1.1 6.8e-30 103.2 0.8 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Dopey_N PF04118.9 EPR80010.1 - 3.3e-68 229.7 8.6 3.3e-68 229.7 5.9 5.3 4 2 0 5 5 5 1 Dopey, N-terminal TFIIS_C PF01096.13 EPR80011.1 - 6.2e-20 70.5 4.6 6.2e-20 70.5 3.2 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPR80011.1 - 1.1e-06 28.1 1.0 1.1e-06 28.1 0.7 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EPR80011.1 - 0.0033 17.6 5.5 0.028 14.7 1.0 2.3 2 0 0 2 2 2 1 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EPR80011.1 - 0.0038 17.4 4.8 0.0089 16.2 0.9 2.2 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Baculo_LEF5_C PF11792.3 EPR80011.1 - 0.0089 15.3 2.8 0.0089 15.3 2.0 2.9 3 1 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain DUF2082 PF09855.4 EPR80011.1 - 0.027 14.3 8.3 1.9 8.3 0.1 3.4 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Terminase_GpA PF05876.7 EPR80011.1 - 0.031 12.6 3.0 0.03 12.6 2.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DZR PF12773.2 EPR80011.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-U1 PF06220.7 EPR80011.1 - 0.15 11.6 2.7 0.3 10.6 1.9 1.5 1 0 0 1 1 1 0 U1 zinc finger Zn_Tnp_IS1595 PF12760.2 EPR80011.1 - 0.46 10.3 10.3 0.094 12.5 1.2 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.8 EPR80011.1 - 0.58 9.8 8.7 1.2 8.8 0.9 2.2 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Cytochrom_c3_2 PF14537.1 EPR80011.1 - 2.1 8.7 8.5 1.4e+02 2.8 5.9 2.3 1 1 0 1 1 1 0 Cytochrome c3 RNHCP PF12647.2 EPR80011.1 - 2.8 7.8 8.8 17 5.3 3.4 2.5 1 1 1 2 2 2 0 RNHCP domain HypA PF01155.14 EPR80011.1 - 2.8 7.6 8.1 0.63 9.7 2.3 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Rpr2 PF04032.11 EPR80011.1 - 3.8 7.4 13.6 2.9e+03 -1.8 9.4 2.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CHY PF05495.7 EPR80011.1 - 3.9 7.7 16.2 6.2 7.0 7.0 2.8 1 1 1 2 2 2 0 CHY zinc finger C1_1 PF00130.17 EPR80011.1 - 4.7 7.0 10.0 1.8 8.3 0.9 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.7 EPR80011.1 - 6.2 6.2 14.9 3.5 7.0 1.4 3.4 2 2 2 4 4 4 0 TFIIB zinc-binding DUF3973 PF13119.1 EPR80011.1 - 6.6 6.7 7.2 32 4.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3973) HAT PF02184.11 EPR80012.1 - 0.00082 19.0 2.2 0.17 11.6 0.1 2.9 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat DUF1925 PF09094.6 EPR80012.1 - 1.5 8.8 8.4 0.11 12.4 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) Ribosomal_S17 PF00366.15 EPR80012.1 - 8 6.5 8.4 27 4.9 0.4 3.4 2 0 0 2 2 2 0 Ribosomal protein S17 Chromo PF00385.19 EPR80013.1 - 1.9e-14 53.0 5.5 6.4e-14 51.3 0.2 2.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EPR80013.1 - 1.2e-07 31.4 0.0 2.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Chromo shadow domain Mg_trans_NIPA PF05653.9 EPR80014.1 - 1.9e-28 99.3 19.0 2e-20 72.9 3.9 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EPR80014.1 - 0.0003 20.8 32.0 0.0041 17.1 6.9 3.5 3 1 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 EPR80014.1 - 0.0038 17.3 3.2 0.0038 17.3 2.2 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter Nodulin_late PF07127.6 EPR80014.1 - 0.047 13.8 0.2 0.047 13.8 0.1 4.5 4 0 0 4 4 4 0 Late nodulin protein Spc7 PF08317.6 EPR80015.1 - 0.01 14.5 16.3 0.016 13.9 11.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF848 PF05852.6 EPR80015.1 - 0.018 14.8 14.8 0.23 11.3 1.4 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sulfotransfer_2 PF03567.9 EPR80015.1 - 0.022 14.4 2.5 0.043 13.4 1.5 1.8 1 1 0 1 1 1 0 Sulfotransferase family APG6 PF04111.7 EPR80015.1 - 0.023 13.7 19.0 0.036 13.1 13.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TraC PF07820.7 EPR80015.1 - 0.041 14.0 6.5 0.078 13.1 0.2 2.4 1 1 1 2 2 2 0 TraC-like protein DASH_Dam1 PF08653.5 EPR80015.1 - 0.26 11.0 2.2 0.65 9.8 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 CALCOCO1 PF07888.6 EPR80015.1 - 0.45 8.7 12.0 0.61 8.3 8.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF342 PF03961.8 EPR80015.1 - 0.9 7.8 23.1 5.6 5.2 15.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 EPR80015.1 - 1.9 8.5 14.0 0.24 11.3 6.1 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EPR80015.1 - 2.3 7.7 17.1 5.4 6.5 11.8 1.7 1 1 0 1 1 1 0 IncA protein DUF948 PF06103.6 EPR80015.1 - 3.4 7.6 5.0 10 6.0 2.4 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4140 PF13600.1 EPR80015.1 - 5.6 7.4 7.0 5.5 7.4 0.2 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cep57_CLD_2 PF14197.1 EPR80015.1 - 6.6 6.7 17.6 12 5.9 8.7 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Histone PF00125.19 EPR80016.1 - 3.6e-25 87.8 0.9 5.3e-25 87.3 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPR80016.1 - 0.0056 16.7 0.4 0.0085 16.1 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPR80016.1 - 0.015 15.0 0.1 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-S PF15630.1 EPR80016.1 - 0.015 15.4 0.1 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF3356 PF11836.3 EPR80016.1 - 0.058 13.2 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) Cofilin_ADF PF00241.15 EPR80017.1 - 8.2e-07 28.9 0.1 1.1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Corona_S1 PF01600.11 EPR80017.1 - 0.0038 15.6 0.4 0.0046 15.3 0.3 1.1 1 0 0 1 1 1 1 Coronavirus S1 glycoprotein DUF814 PF05670.8 EPR80018.1 - 1.5e-12 47.2 0.5 3.2e-10 39.7 0.3 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF814) DUF3441 PF11923.3 EPR80018.1 - 0.0013 18.2 0.1 0.0075 15.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) HAD_2 PF13419.1 EPR80019.1 - 9e-16 58.5 0.1 1.1e-15 58.2 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPR80019.1 - 0.0071 15.9 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Acid Phosphatase NIF PF03031.13 EPR80019.1 - 0.26 10.9 2.2 5.5 6.6 0.2 2.4 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase E1-E2_ATPase PF00122.15 EPR80020.1 - 9.9e-25 86.9 0.1 9.4e-24 83.7 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPR80020.1 - 1.9e-16 61.1 0.8 2.8e-15 57.3 0.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPR80020.1 - 1.4e-10 41.7 0.1 3.8e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPR80020.1 - 8.1e-07 28.9 0.1 8.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPR80020.1 - 0.0018 17.8 3.8 0.04 13.4 0.1 3.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF1628 PF07790.6 EPR80020.1 - 0.27 12.0 2.7 20 5.9 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1628) SNF2_N PF00176.18 EPR80021.1 - 4.6e-54 183.2 0.7 8.9e-54 182.2 0.5 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPR80021.1 - 3.2e-15 55.7 0.0 1.1e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2636 PF11120.3 EPR80022.1 - 0.0077 15.7 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2636) DUF3180 PF11377.3 EPR80022.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) CBFB_NFYA PF02045.10 EPR80023.1 - 2.9e-18 66.1 0.6 4.6e-18 65.4 0.4 1.3 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TBCA PF02970.11 EPR80024.1 - 0.012 15.7 2.4 0.02 14.9 1.6 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor A DUF2522 PF10747.4 EPR80024.1 - 0.043 13.8 3.0 0.065 13.2 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2522) MIF4G_like_2 PF09090.6 EPR80024.1 - 0.068 12.3 3.6 0.11 11.6 0.4 2.2 1 1 1 2 2 2 0 MIF4G like Borrelia_REV PF03978.8 EPR80024.1 - 0.12 12.1 7.6 0.14 11.9 5.3 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF4297 PF14130.1 EPR80024.1 - 0.18 11.6 2.9 0.2 11.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) DUF2779 PF11074.3 EPR80024.1 - 0.22 11.5 2.6 0.28 11.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Dimer_Tnp_Tn5 PF02281.11 EPR80025.1 - 0.12 12.4 1.1 0.27 11.3 0.1 2.1 1 1 1 2 2 2 0 Transposase Tn5 dimerisation domain YqfQ PF14181.1 EPR80025.1 - 0.27 11.2 3.7 0.47 10.4 2.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein UCH PF00443.24 EPR80026.1 - 0.032 13.3 0.0 3.6 6.6 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF2733 PF10813.3 EPR80026.1 - 0.041 13.4 0.3 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) RRF PF01765.14 EPR80028.1 - 0.03 13.8 7.5 0.043 13.2 5.2 1.3 1 1 0 1 1 1 0 Ribosome recycling factor zf-C3H1 PF10650.4 EPR80028.1 - 5.6 6.5 14.1 3.2 7.2 0.5 3.2 3 0 0 3 3 3 0 Putative zinc-finger domain RIX1 PF08167.7 EPR80029.1 - 0.056 13.1 0.3 0.13 11.9 0.2 1.6 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis tRNA-synt_1 PF00133.17 EPR80030.1 - 5.5e-26 90.7 0.4 6.9e-13 47.4 0.2 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPR80030.1 - 4.4e-23 81.5 4.7 3.3e-11 42.4 0.0 4.3 3 1 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EPR80030.1 - 6.7e-09 35.2 6.2 6.6e-08 32.0 3.8 2.9 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PHD PF00628.24 EPR80031.1 - 6.8e-08 32.0 12.9 9.3e-08 31.6 7.0 2.3 2 0 0 2 2 2 1 PHD-finger MarR PF01047.17 EPR80031.1 - 3.7e-05 23.3 0.0 7.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 EPR80031.1 - 0.0079 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding PHD_2 PF13831.1 EPR80031.1 - 0.037 13.3 2.9 0.1 11.9 2.0 1.8 1 0 0 1 1 1 0 PHD-finger MarR_2 PF12802.2 EPR80031.1 - 0.042 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 MarR family Ftsk_gamma PF09397.5 EPR80031.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain TrmB PF01978.14 EPR80031.1 - 0.097 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Toxin_54 PF15533.1 EPR80032.1 - 0.015 15.5 0.1 0.051 13.8 0.1 1.9 1 0 0 1 1 1 0 Putative toxin 54 DEAD PF00270.24 EPR80034.1 - 6.2e-25 87.6 1.1 2e-24 86.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPR80034.1 - 8.3e-15 54.4 0.1 2.2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPR80034.1 - 1.3e-07 31.6 0.0 1.3e-07 31.6 0.0 4.1 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPR80034.1 - 9.9e-05 22.4 1.3 0.0003 20.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPR80034.1 - 0.00019 21.0 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EPR80034.1 - 0.00045 19.2 0.0 0.0021 17.0 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein DNA_pol_B PF00136.16 EPR80035.1 - 3e-99 332.9 13.7 3e-99 332.9 9.5 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EPR80035.1 - 4.1 6.7 13.4 12 5.1 3.6 3.4 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger Arf PF00025.16 EPR80036.1 - 1.3e-23 83.1 0.3 1.5e-23 82.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPR80036.1 - 2.5e-07 29.7 1.5 1.1e-05 24.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EPR80036.1 - 3.4e-07 30.2 0.0 5.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPR80036.1 - 1.4e-06 27.5 0.1 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPR80036.1 - 6.9e-06 25.3 0.0 9e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPR80036.1 - 0.00015 22.2 0.1 0.00032 21.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EPR80036.1 - 0.00029 20.2 0.1 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Ras family DUF4410 PF14366.1 EPR80037.1 - 1.2 8.9 3.8 7.7 6.2 2.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) EF-hand_7 PF13499.1 EPR80039.1 - 1.1e-08 35.1 2.0 4.9e-06 26.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPR80039.1 - 2.8e-05 23.6 0.7 0.00018 21.1 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EPR80039.1 - 3.9e-05 22.6 1.2 0.00015 20.8 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EPR80039.1 - 0.00083 18.9 5.4 0.0042 16.6 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain pair DUF3875 PF12991.2 EPR80039.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) Imm45 PF15603.1 EPR80039.1 - 0.087 12.9 1.5 0.14 12.3 0.2 2.0 2 1 1 3 3 3 0 Immunity protein 45 HTH_DeoR PF08220.7 EPR80039.1 - 0.17 11.4 0.6 0.6 9.6 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain LSM PF01423.17 EPR80040.1 - 4.4e-15 54.9 3.0 6.5e-15 54.4 2.1 1.3 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPR80040.1 - 0.00085 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain WD40 PF00400.27 EPR80043.1 - 3.3e-07 29.9 3.6 0.023 14.5 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat bPH_3 PF14470.1 EPR80043.1 - 0.0065 16.7 2.0 0.0065 16.7 1.4 2.6 1 1 2 3 3 3 1 Bacterial PH domain PQQ_3 PF13570.1 EPR80043.1 - 0.15 12.3 0.2 38 4.7 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain DUF2415 PF10313.4 EPR80043.1 - 0.16 11.7 0.2 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF3911 PF13050.1 EPR80043.1 - 1.3 9.1 11.0 0.23 11.6 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3911) LRR_8 PF13855.1 EPR80044.1 - 4.1e-09 36.0 34.1 4.5e-06 26.3 1.6 6.3 7 1 0 7 7 7 4 Leucine rich repeat LRR_1 PF00560.28 EPR80044.1 - 2.1e-08 33.0 32.4 0.09 12.8 0.0 10.6 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_4 PF12799.2 EPR80044.1 - 2.2e-06 27.1 48.3 0.049 13.2 1.5 9.1 5 3 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPR80044.1 - 0.22 11.8 17.9 14 6.3 0.0 8.3 8 0 0 8 8 8 0 Leucine rich repeat Rad52_Rad22 PF04098.10 EPR80045.1 - 2.6e-47 160.3 1.6 3.3e-47 160.0 1.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein dDENN PF03455.14 EPR80046.1 - 0.03 14.3 0.1 0.69 10.0 0.0 2.4 2 1 0 2 2 2 0 dDENN domain RNA_pol_Rpb1_1 PF04997.7 EPR80047.1 - 2.2e-106 355.9 0.0 2.2e-106 355.9 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPR80047.1 - 6.7e-90 301.0 1.5 6.7e-90 301.0 1.0 2.7 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPR80047.1 - 2.3e-64 216.3 0.0 2.3e-64 216.3 0.0 3.6 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPR80047.1 - 1.1e-47 161.7 0.9 1.1e-47 161.7 0.7 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPR80047.1 - 1.1e-37 128.0 0.2 1.1e-37 128.0 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 EPR80047.1 - 1.4e-28 99.3 10.0 4.5e-28 97.6 7.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 7 Glyco_hydro_38 PF01074.17 EPR80047.1 - 0.033 13.4 0.1 0.073 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain AcetDehyd-dimer PF09290.6 EPR80047.1 - 0.035 14.0 1.8 0.089 12.6 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation MIP-T3 PF10243.4 EPR80048.1 - 5 5.4 48.7 7.1 4.9 33.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PHA_synth_III_E PF09712.5 EPR80049.1 - 0.016 14.6 0.1 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF4375 PF14300.1 EPR80049.1 - 0.043 13.8 3.0 0.053 13.5 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) TBPIP PF07106.8 EPR80049.1 - 0.047 13.2 9.7 0.045 13.2 5.5 1.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) VSG_B PF13206.1 EPR80049.1 - 0.096 11.7 0.6 0.11 11.6 0.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain MCPsignal PF00015.16 EPR80049.1 - 0.12 11.9 2.1 0.11 12.0 0.8 1.4 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain TerB-N PF13208.1 EPR80049.1 - 0.14 11.5 2.2 2.4 7.5 0.1 2.0 1 1 1 2 2 2 0 TerB-N DUF1098 PF06497.6 EPR80049.1 - 0.15 12.0 2.2 11 6.1 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1098) ThiF PF00899.16 EPR80049.1 - 0.19 11.5 1.1 0.26 11.1 0.8 1.2 1 0 0 1 1 1 0 ThiF family DUF4110 PF13422.1 EPR80049.1 - 0.32 10.8 3.7 1.2 9.0 2.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) Latarcin PF10279.4 EPR80049.1 - 0.32 11.2 4.8 1.1 9.5 3.3 1.9 1 1 0 1 1 1 0 Latarcin precursor tRNA-synt_2 PF00152.15 EPR80049.1 - 1 8.0 7.1 1.1 7.9 4.9 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Radical_SAM PF04055.16 EPR80050.1 - 2.9e-15 56.8 0.3 7.4e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EPR80050.1 - 8.9e-09 35.2 0.1 1.9e-07 31.0 0.1 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family NGP1NT PF08153.7 EPR80051.1 - 1.1e-22 80.3 1.3 1.1e-22 80.3 0.9 2.3 3 0 0 3 3 3 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EPR80051.1 - 1.6e-17 63.5 0.6 9.7e-14 51.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPR80051.1 - 3.1e-06 26.5 0.2 1.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EPR80051.1 - 8.6e-05 21.8 0.7 0.0038 16.4 0.0 2.9 2 1 1 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPR80051.1 - 0.00036 20.0 0.1 0.29 10.5 0.0 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IcmL PF11393.3 EPR80051.1 - 0.0024 17.8 0.1 0.023 14.6 0.0 2.7 2 1 1 3 3 3 1 Macrophage killing protein with similarity to conjugation protein DUF258 PF03193.11 EPR80051.1 - 0.0064 15.6 0.1 0.034 13.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPR80051.1 - 0.016 15.0 7.5 0.079 12.7 0.1 4.0 2 2 0 2 2 2 0 Dynamin family Cpn60_TCP1 PF00118.19 EPR80052.1 - 9.9e-97 324.5 8.9 1.5e-96 323.9 6.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DMA PF03474.9 EPR80052.1 - 0.024 14.4 0.2 0.076 12.8 0.1 1.8 1 0 0 1 1 1 0 DMRTA motif tRNA-synt_2c PF01411.14 EPR80053.1 - 2.5e-162 541.0 7.8 2.5e-162 541.0 5.4 2.4 2 1 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EPR80053.1 - 1.2e-13 50.7 1.2 1.2e-13 50.7 0.8 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain RNase_P_p30 PF01876.11 EPR80054.1 - 4.9e-23 81.0 0.0 6.9e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Baculo_PP31 PF05311.6 EPR80054.1 - 0.015 14.5 1.3 0.015 14.5 0.9 1.7 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) adh_short PF00106.20 EPR80055.1 - 1.1e-17 64.4 0.0 1.5e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPR80055.1 - 4.8e-07 29.6 0.0 6.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPR80055.1 - 3.6e-05 23.2 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPR80055.1 - 0.00057 18.8 0.1 0.00078 18.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPR80055.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPR80055.1 - 0.0046 15.9 0.1 0.0066 15.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EPR80055.1 - 0.0073 16.3 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Wax2_C PF12076.3 EPR80055.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain F420_oxidored PF03807.12 EPR80055.1 - 0.093 13.1 0.1 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_S25 PF03297.10 EPR80056.1 - 1.7e-16 60.1 7.2 2e-16 59.9 5.0 1.1 1 0 0 1 1 1 1 S25 ribosomal protein SecIII_SopE_N PF05364.9 EPR80056.1 - 0.0015 18.2 1.0 0.0027 17.5 0.4 1.7 1 1 0 1 1 1 1 Salmonella type III secretion SopE effector N-terminus DDRGK PF09756.4 EPR80056.1 - 0.0043 16.4 3.7 0.0049 16.2 2.5 1.1 1 0 0 1 1 1 1 DDRGK domain TMP_2 PF06791.8 EPR80056.1 - 0.057 13.0 0.3 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein 7TM_GPCR_Srab PF10292.4 EPR80056.1 - 0.14 10.8 0.3 0.17 10.5 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Rrf2 PF02082.15 EPR80056.1 - 0.15 12.2 0.3 0.54 10.4 0.1 1.9 1 1 1 2 2 2 0 Transcriptional regulator WASH_WAHD PF11945.3 EPR80056.1 - 0.64 9.2 3.4 0.68 9.1 1.5 1.8 1 1 1 2 2 2 0 WAHD domain of WASH complex Metallophos PF00149.23 EPR80057.1 - 1e-31 109.8 0.5 1.8e-31 109.1 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPR80057.1 - 0.0003 20.6 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S13_N PF08069.7 EPR80058.1 - 1.5e-23 82.3 0.0 3.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EPR80058.1 - 1.9e-12 46.7 0.1 3.1e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3860 PF12976.2 EPR80058.1 - 0.039 13.7 0.0 2.5 7.9 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) Pkinase PF00069.20 EPR80059.1 - 6.5e-58 195.9 0.0 8e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR80059.1 - 6.9e-25 87.5 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EPR80059.1 - 0.014 14.2 0.1 0.024 13.4 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 EPR80060.1 - 9.3e-16 58.0 8.9 5.4e-15 55.5 3.1 2.4 1 1 1 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 EPR80060.1 - 6.1e-08 32.6 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPR80060.1 - 0.0016 17.6 0.7 0.0026 16.9 0.5 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Zip PF02535.17 EPR80061.1 - 0.13 11.2 3.4 0.13 11.1 0.0 2.2 2 1 0 2 2 2 0 ZIP Zinc transporter DUF2201_N PF13203.1 EPR80061.1 - 5 6.1 10.7 5 6.2 3.9 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Pex14_N PF04695.8 EPR80061.1 - 6.6 6.7 29.5 0.52 10.3 0.5 4.4 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC37_C PF08564.5 EPR80061.1 - 6.6 6.6 15.5 3.3 7.6 6.1 2.9 2 0 0 2 2 2 0 Cdc37 C terminal domain ubiquitin PF00240.18 EPR80062.1 - 6.7e-23 79.8 0.1 7.8e-23 79.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPR80062.1 - 8.1e-12 44.6 0.2 9.9e-12 44.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPR80062.1 - 1.4e-06 28.4 0.2 3.1e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPR80062.1 - 0.00052 19.8 0.1 0.0029 17.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPR80062.1 - 0.013 15.7 0.1 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Mur_ligase_C PF02875.16 EPR80062.1 - 0.052 13.5 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Med31 PF05669.7 EPR80063.1 - 2.5e-20 72.1 6.0 2.7e-20 71.9 4.1 1.0 1 0 0 1 1 1 1 SOH1 LMBR1 PF04791.11 EPR80064.1 - 0.091 11.3 2.5 0.061 11.8 0.5 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein Gag_spuma PF03276.9 EPR80064.1 - 6.2 5.0 7.6 8.7 4.5 5.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein ArfGap PF01412.13 EPR80065.1 - 1.5e-19 69.9 5.7 1.5e-19 69.9 4.0 2.4 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf Nbl1_Borealin_N PF10444.4 EPR80065.1 - 0.85 9.0 4.1 0.72 9.2 0.5 2.3 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal FliD_N PF02465.13 EPR80065.1 - 7.6 6.9 7.4 3.3 8.1 1.2 2.4 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BING4CT PF08149.6 EPR80066.1 - 5e-22 77.2 0.3 2.2e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 BING4CT (NUC141) domain PGA_cap PF09587.5 EPR80066.1 - 0.0085 15.4 2.3 0.01 15.2 1.6 1.2 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap ICMT PF04140.9 EPR80067.1 - 3.2e-07 30.4 3.9 3.2e-07 30.4 2.7 2.7 1 1 2 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EPR80067.1 - 3.2 6.9 8.7 4.7 6.4 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) zf-met PF12874.2 EPR80068.1 - 7.5e-05 22.7 2.0 0.00014 21.9 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPR80068.1 - 0.013 15.6 3.2 0.028 14.5 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding HTH_19 PF12844.2 EPR80068.1 - 0.039 13.9 0.4 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Parathyroid PF01279.12 EPR80068.1 - 0.041 14.5 0.1 0.069 13.7 0.0 1.5 1 1 0 1 1 1 0 Parathyroid hormone family FpoO PF10621.4 EPR80068.1 - 0.13 12.3 1.7 0.4 10.7 1.0 1.8 1 1 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF2404 PF10296.4 EPR80069.1 - 0.00086 19.3 3.4 0.032 14.3 1.6 3.7 3 1 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) HAD_2 PF13419.1 EPR80070.1 - 6e-15 55.9 0.0 3e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EPR80070.1 - 0.0071 15.9 5.4 0.96 9.0 0.0 3.3 3 1 0 3 3 3 2 Acid Phosphatase Ppx-GppA PF02541.11 EPR80070.1 - 0.082 12.0 0.4 0.56 9.3 0.1 2.1 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Hydrolase_like PF13242.1 EPR80070.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like PFK PF00365.15 EPR80071.1 - 2.3e-155 515.6 0.8 1.3e-102 342.5 0.3 3.2 2 1 1 3 3 3 3 Phosphofructokinase DNA_ligase_A_M PF01068.16 EPR80072.1 - 1.3e-40 138.9 7.1 1.3e-39 135.7 3.3 3.0 2 1 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPR80072.1 - 3.4e-29 101.9 4.8 6.6e-29 100.9 3.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPR80072.1 - 2.5e-18 66.2 0.0 6e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DUF3014 PF11219.3 EPR80072.1 - 0.0097 15.7 0.2 0.024 14.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3014) C2-set PF05790.10 EPR80072.1 - 0.013 15.4 1.9 0.046 13.7 1.3 2.0 1 0 0 1 1 1 0 Immunoglobulin C2-set domain Trehalase PF01204.13 EPR80073.1 - 1.4e-111 373.6 5.5 1.4e-111 373.6 3.8 1.9 1 1 1 2 2 2 1 Trehalase tRNA-synt_1b PF00579.20 EPR80074.1 - 2.3e-22 79.4 0.0 5.1e-22 78.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2532 PF10811.3 EPR80074.1 - 0.006 16.4 0.7 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2532) Abhydrolase_2 PF02230.11 EPR80076.1 - 1.5e-25 89.9 0.1 1.9e-25 89.6 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPR80076.1 - 7.9e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPR80076.1 - 2.5e-10 40.1 0.1 6.8e-10 38.7 0.1 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPR80076.1 - 7.1e-06 26.0 0.0 0.00032 20.6 0.0 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPR80076.1 - 0.00099 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 EPR80076.1 - 0.005 15.7 0.1 0.026 13.4 0.1 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 EPR80076.1 - 0.029 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.3 EPR80076.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EPR80076.1 - 0.048 13.2 0.1 0.19 11.2 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EPR80076.1 - 0.073 11.5 0.1 0.14 10.6 0.0 1.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF915 PF06028.6 EPR80076.1 - 0.1 11.6 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FtsJ PF01728.14 EPR80077.1 - 6e-57 192.5 0.1 7.7e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase P16-Arc PF04699.9 EPR80078.1 - 0.11 12.4 1.1 0.18 11.8 0.8 1.4 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Rep_fac_C PF08542.6 EPR80078.1 - 0.19 11.7 2.0 0.44 10.5 1.2 2.0 1 1 0 1 1 1 0 Replication factor C C-terminal domain Nucleoporin_FG PF13634.1 EPR80079.1 - 0.063 13.5 3.0 0.077 13.2 0.3 2.3 2 1 0 2 2 2 0 Nucleoporin FG repeat region PH PF00169.24 EPR80080.1 - 0.00081 19.5 0.5 0.00081 19.5 0.3 2.9 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EPR80080.1 - 0.014 15.6 0.7 0.014 15.6 0.5 3.5 3 1 1 4 4 4 0 Pleckstrin homology domain Ribosomal_L7Ae PF01248.21 EPR80081.1 - 9.8e-16 57.0 0.0 1.1e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hpr_kinase_N PF02603.11 EPR80081.1 - 0.052 13.2 0.1 0.065 12.9 0.0 1.3 1 1 0 1 1 1 0 HPr Serine kinase N terminus Dak1 PF02733.12 EPR80082.1 - 0.18 10.3 0.9 0.35 9.4 0.7 1.3 1 0 0 1 1 1 0 Dak1 domain NifU PF01106.12 EPR80082.1 - 6.6 6.5 7.7 2.2 8.1 0.3 3.2 3 0 0 3 3 3 0 NifU-like domain Tna_leader PF08053.6 EPR80083.1 - 0.024 14.0 0.8 0.1 11.9 0.6 2.1 1 0 0 1 1 1 0 Tryptophanese operon leader peptide EIF_2_alpha PF07541.7 EPR80085.1 - 2.4e-13 49.8 2.4 2.4e-13 49.8 1.7 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EPR80085.1 - 2e-09 37.4 0.7 5.4e-09 36.0 0.5 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Sigma_reg_N PF13800.1 EPR80085.1 - 1.4 9.0 7.5 4.5 7.3 5.2 1.9 1 0 0 1 1 1 0 Sigma factor regulator N-terminal RNA_pol_Rpb2_6 PF00562.23 EPR80086.1 - 2.7e-126 421.3 0.3 4e-126 420.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPR80086.1 - 1.5e-60 203.6 0.1 2.3e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPR80086.1 - 2.9e-37 127.9 0.1 6.1e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPR80086.1 - 2.9e-28 97.9 0.0 7.2e-28 96.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EPR80086.1 - 4.8e-26 90.2 0.9 9.2e-26 89.4 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EPR80086.1 - 5.3e-21 74.1 0.0 1.7e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EPR80086.1 - 3.5e-19 68.5 1.9 7.6e-19 67.4 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Prok-RING_2 PF14445.1 EPR80086.1 - 0.15 12.0 1.2 0.33 10.9 0.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 CobT PF06213.7 EPR80087.1 - 0.81 8.7 9.1 1 8.4 6.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Baculo_PEP_C PF04513.7 EPR80088.1 - 0.022 14.5 8.9 0.08 12.7 3.7 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG5 PF10392.4 EPR80088.1 - 1.2 9.0 12.7 0.041 13.8 1.4 3.1 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF1938 PF09153.5 EPR80088.1 - 2.1 8.2 16.3 0.4 10.5 0.2 4.9 4 2 1 5 5 5 0 Domain of unknown function (DUF1938) NEP PF10167.4 EPR80088.1 - 4 7.1 12.1 0.45 10.2 2.7 3.6 3 1 1 4 4 4 0 Uncharacterised conserved protein Utp14 PF04615.8 EPR80089.1 - 5.8e-23 80.9 32.9 1e-21 76.8 3.2 2.2 2 0 0 2 2 2 2 Utp14 protein Sarcoglycan_1 PF04790.8 EPR80089.1 - 0.08 12.0 1.8 2.7 7.0 0.0 2.2 1 1 0 2 2 2 0 Sarcoglycan complex subunit protein Brr6_like_C_C PF10104.4 EPR80090.1 - 3.7e-19 68.5 1.8 3.7e-19 68.5 1.3 2.6 2 1 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF912 PF06024.7 EPR80090.1 - 1.8 8.6 5.4 0.63 10.1 0.9 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SF3b1 PF08920.5 EPR80091.1 - 0.04 13.9 0.8 0.15 12.1 0.6 1.9 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EPR80091.1 - 0.099 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats ubiquitin PF00240.18 EPR80092.1 - 5e-05 22.6 1.3 9.8e-05 21.6 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPR80092.1 - 0.0023 17.5 3.2 0.0045 16.6 2.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PB1 PF00564.19 EPR80092.1 - 0.078 12.6 0.3 0.26 10.9 0.2 1.9 1 0 0 1 1 1 0 PB1 domain Zip PF02535.17 EPR80093.1 - 2.5 7.0 12.6 6.6 5.6 8.7 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter GTP_EFTU PF00009.22 EPR80094.1 - 1.5e-55 187.5 0.0 2.5e-55 186.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPR80094.1 - 4.9e-28 97.0 0.0 1.2e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPR80094.1 - 1.7e-20 72.6 0.0 4.4e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EPR80094.1 - 2.6e-13 49.6 0.0 6.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPR80094.1 - 6.8e-12 45.3 0.7 1.8e-11 43.9 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EPR80094.1 - 0.045 12.9 0.0 0.13 11.4 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CBFD_NFYB_HMF PF00808.18 EPR80095.1 - 6.9e-15 54.8 0.5 9.6e-15 54.4 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPR80095.1 - 9e-06 25.7 0.1 1.1e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ATP-cone PF03477.11 EPR80095.1 - 0.015 15.7 0.2 0.016 15.6 0.1 1.3 1 0 0 1 1 1 0 ATP cone domain Hpr_kinase_N PF02603.11 EPR80095.1 - 0.038 13.6 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase N terminus Ribosomal_L24e PF01246.15 EPR80097.1 - 5.8e-24 83.7 4.6 1.1e-23 82.8 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e Ribosomal_L31e PF01198.14 EPR80098.1 - 9.6e-16 57.2 0.9 1.3e-15 56.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CTX_RstB PF07459.6 EPR80098.1 - 0.024 14.5 0.0 0.031 14.1 0.0 1.3 1 1 0 1 1 1 0 CTX phage RstB protein HrpB_C PF08482.5 EPR80098.1 - 0.069 13.2 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 ATP-dependent helicase C-terminal Ribosomal_S8 PF00410.14 EPR80099.1 - 0.013 15.3 0.3 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 DUF4539 PF15072.1 EPR80099.1 - 0.12 12.0 0.1 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) RPEL PF02755.10 EPR80100.1 - 0.0012 18.1 0.4 0.0012 18.1 0.3 2.6 3 1 0 3 3 3 1 RPEL repeat CDO_I PF05995.7 EPR80100.1 - 0.0086 15.2 0.2 0.011 14.9 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I TM1586_NiRdase PF14512.1 EPR80100.1 - 0.011 14.9 0.8 0.013 14.7 0.5 1.2 1 0 0 1 1 1 0 Putative TM nitroreductase NusB PF01029.13 EPR80100.1 - 0.096 12.6 2.6 0.12 12.3 1.8 1.2 1 0 0 1 1 1 0 NusB family PAP_assoc PF03828.14 EPR80100.1 - 0.14 12.1 0.3 0.23 11.4 0.2 1.6 1 1 0 1 1 1 0 Cid1 family poly A polymerase Takusan PF04822.8 EPR80100.1 - 3.5 7.4 10.8 5.8 6.7 7.5 1.3 1 0 0 1 1 1 0 Takusan MMR_HSR1 PF01926.18 EPR80102.1 - 2.9e-21 75.5 1.1 5e-18 65.1 0.2 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPR80102.1 - 2.8e-09 36.4 0.3 5.4e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EPR80102.1 - 9.1e-07 28.2 0.2 2.5e-06 26.7 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EPR80102.1 - 7.6e-06 26.4 0.2 0.002 18.6 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EPR80102.1 - 1.8e-05 24.6 3.6 0.062 13.1 0.1 3.8 2 2 2 4 4 4 2 Dynamin family PduV-EutP PF10662.4 EPR80102.1 - 0.00086 18.8 0.3 0.64 9.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EPR80102.1 - 0.0013 17.9 0.1 0.0046 16.2 0.0 2.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AIG1 PF04548.11 EPR80102.1 - 0.0016 17.6 1.1 0.004 16.2 0.1 2.2 3 0 0 3 3 3 1 AIG1 family Ras PF00071.17 EPR80102.1 - 0.022 14.1 1.0 0.068 12.5 0.1 2.1 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.1 EPR80102.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EPR80102.1 - 0.042 13.2 0.1 8.1 5.8 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EPR80102.1 - 0.085 12.5 0.4 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EPR80102.1 - 0.11 12.2 9.1 0.19 11.3 2.9 3.0 1 1 1 2 2 2 0 Archaeal ATPase GTP_EFTU PF00009.22 EPR80102.1 - 0.11 11.8 2.9 5.6 6.3 0.2 3.1 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EPR80102.1 - 0.6 10.9 3.8 0.82 10.5 0.2 2.8 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EPR80102.1 - 9.1 6.6 9.5 0.73 10.1 0.6 3.2 2 2 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EPR80103.1 - 1.5e-15 56.8 29.9 1.5e-15 56.8 20.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EPR80103.1 - 1.2e-07 30.8 28.1 1.6e-07 30.4 19.5 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter PDR_CDR PF06422.7 EPR80103.1 - 0.039 13.5 0.0 0.039 13.5 0.0 3.6 5 0 0 5 5 5 0 CDR ABC transporter SIR2 PF02146.12 EPR80105.1 - 4e-36 124.4 0.1 6.5e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Sir2 family BTB PF00651.26 EPR80105.1 - 0.0029 17.5 0.1 0.0094 15.9 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain zf-trcl PF13451.1 EPR80105.1 - 0.96 9.1 5.4 2.5 7.7 3.7 1.7 1 0 0 1 1 1 0 Probable zinc-binding domain Phage_int_SAM_3 PF14659.1 EPR80105.1 - 3.7 7.8 8.3 0.46 10.7 0.7 3.1 4 1 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain Arf PF00025.16 EPR80106.1 - 6.4e-35 119.9 0.0 7.5e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPR80106.1 - 6.3e-14 51.4 3.7 5.1e-10 38.6 0.3 3.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EPR80106.1 - 4e-11 42.5 0.0 5.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPR80106.1 - 1.1e-07 32.3 0.0 2.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPR80106.1 - 1.6e-07 31.3 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPR80106.1 - 5.5e-06 25.6 0.0 7.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPR80106.1 - 7.6e-06 25.4 0.0 0.00075 18.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EPR80106.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Vir_act_alpha_C PF10400.4 EPR80108.1 - 0.078 13.3 4.7 2.1 8.7 0.1 3.0 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF1664 PF07889.7 EPR80108.1 - 1.2 8.9 34.7 0.039 13.7 2.4 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EPR80108.1 - 2.2 8.1 71.4 4.7 7.0 18.1 3.6 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nop PF01798.13 EPR80109.1 - 3.6e-51 172.3 0.1 7.5e-51 171.3 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPR80109.1 - 2.2e-19 68.9 0.8 7.7e-19 67.2 0.5 2.0 1 0 0 1 1 1 1 NOSIC (NUC001) domain BCDHK_Adom3 PF10436.4 EPR80109.1 - 0.12 11.8 1.7 0.66 9.4 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase ETC_C1_NDUFA5 PF04716.9 EPR80109.1 - 0.29 10.6 1.6 1.3 8.5 0.0 2.8 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF848 PF05852.6 EPR80109.1 - 5.8 6.7 11.7 0.32 10.8 1.4 2.7 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) PAXNEB PF05625.6 EPR80110.1 - 4.2e-07 29.1 7.6 0.00091 18.1 1.6 2.5 1 1 1 3 3 3 2 PAXNEB protein SMC_N PF02463.14 EPR80111.1 - 6.5e-26 90.9 78.6 6.5e-26 90.9 54.5 5.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPR80111.1 - 2.3e-24 85.6 0.1 1.2e-23 83.3 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 EPR80111.1 - 2e-05 23.9 0.0 4.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EPR80111.1 - 0.0034 17.3 19.5 0.0034 17.3 13.5 7.1 2 1 3 5 5 5 1 AAA domain ABC_tran PF00005.22 EPR80111.1 - 0.13 12.5 0.0 0.13 12.5 0.0 6.8 3 2 1 4 4 4 0 ABC transporter Fzo_mitofusin PF04799.8 EPR80112.1 - 0.05 12.9 0.4 0.05 12.9 0.3 3.3 2 1 1 3 3 3 0 fzo-like conserved region Arm PF00514.18 EPR80113.1 - 0.15 11.9 0.1 0.36 10.7 0.1 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat TPP1 PF10341.4 EPR80114.1 - 7.4e-08 32.3 1.5 4.3e-07 29.8 0.1 3.2 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD LRR_8 PF13855.1 EPR80115.1 - 7.7e-22 76.8 67.1 8.5e-07 28.6 3.5 9.1 6 3 3 9 9 9 6 Leucine rich repeat LRR_4 PF12799.2 EPR80115.1 - 6.7e-20 70.2 79.0 2.6e-05 23.7 2.4 11.1 8 2 4 12 12 12 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPR80115.1 - 7.6e-09 34.4 67.2 1.7 8.9 0.1 16.4 17 1 0 17 17 17 8 Leucine Rich Repeat LRR_7 PF13504.1 EPR80115.1 - 6.8e-08 31.4 36.2 1.1 9.7 0.0 13.4 13 0 0 13 13 13 3 Leucine rich repeat LRR_6 PF13516.1 EPR80115.1 - 1.3 9.2 53.7 4 7.8 0.0 12.0 12 1 1 13 13 13 0 Leucine Rich repeat LRR_4 PF12799.2 EPR80116.1 - 1.1e-34 117.4 65.0 3.2e-07 29.8 3.9 9.9 6 3 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPR80116.1 - 1.9e-29 101.1 54.9 1.1e-09 37.8 2.9 7.9 4 2 5 9 9 9 9 Leucine rich repeat LRR_1 PF00560.28 EPR80116.1 - 7.9e-17 58.7 60.9 0.066 13.2 0.1 16.0 13 2 3 16 16 16 11 Leucine Rich Repeat LRR_7 PF13504.1 EPR80116.1 - 1.5e-08 33.4 32.6 0.26 11.6 0.1 13.4 13 0 0 13 13 13 2 Leucine rich repeat DS PF01916.12 EPR80117.1 - 3.5e-61 206.9 1.2 4.1e-61 206.6 0.8 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase NadA PF02445.11 EPR80117.1 - 0.035 12.9 0.1 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein eIF-6 PF01912.13 EPR80118.1 - 3.1e-74 248.3 0.3 3.9e-74 248.0 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family Thymidylate_kin PF02223.12 EPR80119.1 - 4.9e-32 110.8 0.1 4.7e-30 104.3 0.0 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EPR80119.1 - 0.00028 20.8 0.0 0.0013 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPR80119.1 - 0.0006 20.1 3.7 0.0011 19.2 1.4 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EPR80119.1 - 0.0015 19.3 1.4 0.0047 17.7 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPR80119.1 - 0.098 12.5 0.5 0.25 11.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain SRF-TF PF00319.13 EPR80121.1 - 2.9e-21 74.4 0.2 4.6e-21 73.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3931 PF13082.1 EPR80121.1 - 0.061 13.1 0.5 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) VPS9 PF02204.13 EPR80122.1 - 8.5e-18 64.2 8.0 8.5e-18 64.2 5.6 2.7 2 2 1 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain DUF3582 PF12122.3 EPR80122.1 - 0.057 13.4 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) Got1 PF04178.7 EPR80124.1 - 2.9e-22 78.9 19.4 4.1e-22 78.5 13.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family TMEM61 PF15105.1 EPR80124.1 - 0.083 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 TMEM61 protein family DUF3816 PF12822.2 EPR80124.1 - 1.6 8.5 20.4 3 7.6 14.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF4181 PF13789.1 EPR80124.1 - 1.9 8.4 14.7 20 5.1 10.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) Na_Ca_ex PF01699.19 EPR80124.1 - 3 7.4 16.9 0.99 9.0 5.8 2.1 1 1 1 2 2 2 0 Sodium/calcium exchanger protein Tub PF01167.13 EPR80125.1 - 7.9e-28 97.0 0.2 5.7e-27 94.2 0.1 2.4 1 1 1 2 2 2 1 Tub family AAA PF00004.24 EPR80126.1 - 2.5e-45 153.9 0.1 6.2e-45 152.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPR80126.1 - 5.1e-09 35.9 0.0 2.1e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPR80126.1 - 9.8e-08 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPR80126.1 - 1.1e-06 28.7 0.1 4.3e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPR80126.1 - 3.5e-06 27.1 0.4 0.00032 20.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPR80126.1 - 3.2e-05 23.0 0.0 6.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EPR80126.1 - 0.00012 22.8 0.1 0.00034 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPR80126.1 - 0.00013 21.6 0.1 0.00027 20.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EPR80126.1 - 0.0003 20.2 0.0 0.00056 19.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EPR80126.1 - 0.0005 19.9 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPR80126.1 - 0.00074 18.3 0.0 0.0017 17.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPR80126.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPR80126.1 - 0.001 18.1 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EPR80126.1 - 0.0014 18.9 0.2 0.01 16.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EPR80126.1 - 0.0019 17.3 0.0 0.0098 15.0 0.0 2.1 1 1 1 2 2 2 1 KaiC PhoH PF02562.11 EPR80126.1 - 0.0022 17.2 0.1 0.047 12.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EPR80126.1 - 0.0023 17.5 0.0 0.0093 15.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EPR80126.1 - 0.0026 17.7 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPR80126.1 - 0.0031 16.4 0.1 0.011 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TMF_TATA_bd PF12325.3 EPR80126.1 - 0.0033 17.1 0.4 0.0033 17.1 0.3 2.3 3 0 0 3 3 2 1 TATA element modulatory factor 1 TATA binding Mg_chelatase PF01078.16 EPR80126.1 - 0.0052 15.9 0.0 0.014 14.5 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 EPR80126.1 - 0.0062 15.0 0.5 0.24 9.7 0.5 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EPR80126.1 - 0.009 15.5 0.3 0.065 12.6 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain CENP-F_leu_zip PF10473.4 EPR80126.1 - 0.011 15.6 0.4 0.011 15.6 0.3 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNA_helicase PF00910.17 EPR80126.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 EPR80126.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPR80126.1 - 0.023 13.5 0.0 0.074 11.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EPR80126.1 - 0.024 14.0 0.1 0.079 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EPR80126.1 - 0.024 14.6 0.0 0.091 12.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EPR80126.1 - 0.031 13.1 0.1 0.097 11.5 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Prefoldin PF02996.12 EPR80126.1 - 0.04 13.5 5.1 0.052 13.1 2.0 2.4 2 1 0 2 2 2 0 Prefoldin subunit NACHT PF05729.7 EPR80126.1 - 0.048 13.3 0.0 0.4 10.3 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EPR80126.1 - 0.054 13.3 0.1 0.43 10.3 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EPR80126.1 - 0.061 13.6 0.3 0.42 10.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EPR80126.1 - 0.53 10.5 3.2 12 6.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain Ribosomal_L36e PF01158.13 EPR80127.1 - 1.2e-18 66.8 6.0 1.4e-18 66.6 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L36e BPL_LplA_LipB PF03099.14 EPR80128.1 - 1e-13 51.3 1.6 8.2e-13 48.4 1.1 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family F-112 PF09645.5 EPR80128.1 - 0.011 15.6 0.4 0.032 14.1 0.1 2.0 2 0 0 2 2 2 0 F-112 protein PTH2 PF01981.11 EPR80130.1 - 8.2e-26 89.9 1.6 3.7e-23 81.4 1.1 2.0 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Diphthamide_syn PF01866.12 EPR80131.1 - 2.8e-80 269.8 2.1 3.3e-80 269.6 1.5 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.20 EPR80134.1 - 8e-53 179.2 1.2 1.1e-52 178.7 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPR80134.1 - 1.8e-25 89.5 0.2 7.7e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPR80134.1 - 6.5e-09 35.1 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPR80134.1 - 0.025 14.2 0.0 0.068 12.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPR80134.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KA1 PF02149.14 EPR80134.1 - 0.097 12.1 0.1 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Kinase associated domain 1 GATA PF00320.22 EPR80135.1 - 0.0018 17.6 2.9 0.0018 17.6 2.0 1.7 2 0 0 2 2 2 1 GATA zinc finger ArdA PF07275.6 EPR80136.1 - 0.18 12.0 5.7 0.051 13.8 1.5 1.9 1 1 1 2 2 2 0 Antirestriction protein (ArdA) Vac14_Fab1_bd PF12755.2 EPR80136.1 - 0.34 11.3 7.1 0.078 13.3 1.0 2.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DUF3899 PF13038.1 EPR80137.1 - 8.3 6.6 8.6 0.74 10.0 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) dCMP_cyt_deam_1 PF00383.17 EPR80139.1 - 3.4e-08 33.0 14.1 1.9e-07 30.6 9.8 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Pex2_Pex12 PF04757.9 EPR80139.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region TSC22 PF01166.13 EPR80139.1 - 0.19 11.6 3.5 0.57 10.1 2.5 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family Arch_flagellin PF01917.11 EPR80139.1 - 2.3 7.7 5.5 0.39 10.3 0.2 1.9 2 0 0 2 2 2 0 Archaebacterial flagellin Eaf7 PF07904.8 EPR80139.1 - 8.3 6.4 9.0 6 6.9 1.2 2.5 2 1 0 2 2 2 0 Chromatin modification-related protein EAF7 XPG_I PF00867.13 EPR80140.1 - 1.2e-31 108.5 0.0 3e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPR80140.1 - 4e-25 88.0 0.1 7.7e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EPR80140.1 - 0.0051 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF2458 PF10454.4 EPR80140.1 - 1.2 9.0 8.0 0.42 10.4 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2458) PI3_PI4_kinase PF00454.22 EPR80141.1 - 1.2e-20 74.0 0.1 1.2e-20 74.0 0.1 3.3 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase YEATS PF03366.11 EPR80142.1 - 2e-23 81.8 0.3 3e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 YEATS family SLA_LP_auto_ag PF05889.8 EPR80142.1 - 0.091 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Ank_2 PF12796.2 EPR80143.1 - 6.4e-13 48.8 0.0 3.1e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPR80143.1 - 8.3e-09 35.7 0.1 0.46 11.0 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EPR80143.1 - 9.5e-09 34.6 0.0 0.076 12.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EPR80143.1 - 4.5e-08 32.5 0.4 0.078 13.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPR80143.1 - 7.1e-07 29.2 0.0 0.09 13.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF2184 PF09950.4 EPR80143.1 - 0.0011 18.1 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2184) DnaJ PF00226.26 EPR80145.1 - 3e-08 33.2 2.7 3.5e-08 33.0 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2 PF00096.21 EPR80145.1 - 1.8e-06 27.9 8.4 0.0035 17.5 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPR80145.1 - 3e-05 24.0 7.6 0.0067 16.6 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPR80145.1 - 3.4e-05 23.5 5.8 0.0055 16.5 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPR80145.1 - 4.5e-05 23.4 10.9 0.011 15.8 1.8 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EPR80145.1 - 0.021 14.9 1.5 0.045 13.8 0.2 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EPR80145.1 - 0.13 12.4 6.1 0.21 11.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EPR80145.1 - 0.5 10.0 7.6 0.31 10.7 0.8 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EPR80145.1 - 1.4 9.3 10.0 1.1 9.6 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain TFIIS_C PF01096.13 EPR80145.1 - 2 8.1 5.5 9.5 5.9 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_2 PF12756.2 EPR80145.1 - 4.6 7.4 15.1 0.33 11.0 0.5 3.1 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-RING_2 PF13639.1 EPR80146.1 - 3.5e-12 45.9 5.2 7.1e-12 44.9 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPR80146.1 - 4.5e-10 39.4 4.3 9.8e-10 38.4 3.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPR80146.1 - 3.5e-07 29.9 1.4 8.4e-07 28.7 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPR80146.1 - 4.1e-07 29.8 6.3 1e-06 28.6 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPR80146.1 - 1.1e-06 28.1 6.0 2.5e-06 27.0 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPR80146.1 - 2.5e-05 23.8 7.5 5.3e-05 22.8 4.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EPR80146.1 - 6.1e-05 22.4 4.3 0.0043 16.4 0.2 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_5 PF14634.1 EPR80146.1 - 6.7e-05 22.5 7.5 0.00024 20.7 4.6 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPR80146.1 - 0.00018 21.3 5.5 0.00037 20.3 3.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPR80146.1 - 0.00029 20.5 2.2 0.00078 19.1 1.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EPR80146.1 - 0.0013 18.2 4.4 0.0029 17.1 2.8 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 EPR80146.1 - 0.0022 17.2 1.9 0.0036 16.5 1.3 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger TerY-C PF15616.1 EPR80146.1 - 0.0047 16.8 0.5 0.0073 16.2 0.3 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain YdjO PF14169.1 EPR80146.1 - 0.043 13.2 1.8 6.9 6.2 0.4 2.3 2 0 0 2 2 2 0 Cold-inducible protein YdjO FANCL_C PF11793.3 EPR80146.1 - 0.085 12.8 6.3 1.5 8.8 1.4 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain TMEM171 PF15471.1 EPR80146.1 - 0.18 10.5 6.0 0.043 12.6 2.0 1.6 2 0 0 2 2 2 0 Transmembrane protein family 171 zf-Di19 PF05605.7 EPR80146.1 - 0.21 11.7 4.1 1.6 8.9 2.8 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.24 EPR80146.1 - 0.4 10.4 5.7 0.82 9.4 4.0 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EPR80146.1 - 0.57 9.9 3.9 1.4 8.6 0.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EPR80146.1 - 0.83 9.7 5.6 2.3 8.3 3.9 1.8 1 1 0 1 1 1 0 RING-variant domain eRF1_1 PF03463.10 EPR80147.1 - 1.2e-20 73.4 1.0 1.2e-20 73.4 0.7 1.8 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.10 EPR80147.1 - 2.6e-13 50.2 2.9 2.8e-13 50.1 0.5 2.2 2 0 0 2 2 2 1 eRF1 domain 3 DHquinase_I PF01487.10 EPR80147.1 - 0.04 13.5 5.9 1.8 8.1 0.0 2.8 3 0 0 3 3 3 0 Type I 3-dehydroquinase Complex1_LYR_2 PF13233.1 EPR80147.1 - 4.9 7.6 5.8 41 4.7 4.1 2.4 1 1 0 1 1 1 0 Complex1_LYR-like TIR PF01582.15 EPR80147.1 - 8.6 5.8 18.4 0.24 10.8 4.3 3.0 2 1 0 3 3 3 0 TIR domain tRNA_U5-meth_tr PF05958.6 EPR80148.1 - 1.1e-11 44.0 1.8 1.1e-11 44.0 1.2 2.5 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EPR80148.1 - 1.6e-10 40.8 0.9 1.6e-10 40.8 0.6 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPR80148.1 - 1.5e-06 28.2 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPR80148.1 - 2.1e-06 28.3 0.0 5.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPR80148.1 - 4e-06 26.2 0.0 8.9e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 EPR80148.1 - 8.2e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EPR80148.1 - 0.0003 21.1 0.0 0.00097 19.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 EPR80148.1 - 0.00037 20.1 0.3 0.00037 20.1 0.2 2.7 3 2 0 3 3 3 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EPR80148.1 - 0.0067 15.5 0.8 0.02 14.0 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein L11 methyltransferase (PrmA) Med28 PF11594.3 EPR80148.1 - 3.1 8.0 15.6 1.7 8.8 0.0 3.6 3 0 0 3 3 3 0 Mediator complex subunit 28 DUF3429 PF11911.3 EPR80150.1 - 0.09 12.7 5.7 0.032 14.2 1.1 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3429) MNHE PF01899.11 EPR80150.1 - 1.1 8.9 8.4 3.1 7.4 0.2 3.4 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit RNA_pol_N PF01194.12 EPR80151.1 - 6.6e-29 99.7 1.9 7.7e-29 99.5 1.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EPR80151.1 - 0.11 12.6 1.9 0.17 11.9 1.3 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7)