# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- UreE_C PF05194.12 KHN68777.1 - 0.026 15.0 0.0 0.07 13.6 0.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain DUF1829 PF08862.10 KHN68777.1 - 0.31 11.6 5.3 0.49 10.9 0.9 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF1829 DUF3698 PF12479.8 KHN68777.1 - 3.2 8.4 7.9 0.55 10.8 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) Peptidase_M1 PF01433.20 KHN68778.1 - 4.5e-47 160.4 10.3 4e-37 127.9 2.2 3.3 4 0 0 4 4 4 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KHN68778.1 - 2e-36 126.0 0.1 7.4e-36 124.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 KHN68778.1 - 1.2e-06 28.3 0.1 4.9e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain DcuC PF03606.15 KHN68779.1 - 0.0027 16.2 2.0 0.0032 16.0 0.7 1.6 1 1 1 2 2 2 1 C4-dicarboxylate anaerobic carrier DUF2070 PF09843.9 KHN68779.1 - 0.14 10.4 5.1 0.18 10.1 5.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Internalin_N PF12354.8 KHN68780.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.6 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Telomerase_RBD PF12009.8 KHN68781.1 - 0.0042 17.2 0.9 0.016 15.3 0.9 2.0 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RFC1 PF08519.12 KHN68781.1 - 0.083 13.1 0.2 0.083 13.1 0.2 2.9 1 1 1 3 3 3 0 Replication factor RFC1 C terminal domain Get5_C PF18514.1 KHN68781.1 - 0.29 10.9 4.4 19 5.1 0.1 4.0 4 0 0 4 4 4 0 Get5 C-terminal domain U3snoRNP10 PF12397.8 KHN68781.1 - 1.8 9.0 4.3 3.6 8.0 0.4 3.2 2 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Arg_decarbox_C PF17944.1 KHN68781.1 - 2 9.1 5.9 4 8.1 0.2 4.2 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension DUF4093 PF13331.6 KHN68781.1 - 3.1 8.3 14.6 0.92 10.0 6.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4093) PDE4_UCR PF18100.1 KHN68781.1 - 3.5 8.3 9.1 24 5.6 1.0 3.8 1 1 3 4 4 4 0 Phosphodiesterase 4 upstream conserved regions (UCR) LcrG PF07216.12 KHN68781.1 - 8.7 6.4 6.8 14 5.7 0.1 3.7 2 1 3 5 5 5 0 LcrG protein LRR_8 PF13855.6 KHN68782.1 - 7.4e-17 60.9 28.3 4.7e-10 39.1 3.6 3.8 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 KHN68782.1 - 8.6e-15 54.6 12.3 3.9e-08 33.5 2.3 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KHN68782.1 - 0.0012 18.4 6.7 0.18 11.3 1.2 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KHN68782.1 - 0.0042 17.4 13.4 1.9 9.4 0.2 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat OGFr_N PF04664.13 KHN68783.1 - 0.038 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region Thymidylat_synt PF00303.19 KHN68784.1 - 9.9e-48 162.6 0.1 1.1e-47 162.5 0.1 1.0 1 0 0 1 1 1 1 Thymidylate synthase SLD5_C PF16922.5 KHN68785.1 - 0.0071 16.5 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Pkinase PF00069.25 KHN68786.1 - 2.5e-49 168.0 0.2 3.2e-49 167.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN68786.1 - 4.5e-23 81.8 0.0 7.1e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KHN68786.1 - 0.0002 21.1 0.2 0.00083 19.0 0.1 1.8 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KHN68786.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KHN68786.1 - 0.02 14.2 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KHN68786.1 - 0.062 12.9 1.0 0.079 12.5 0.3 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase PDGF_N PF04692.13 KHN68786.1 - 0.34 11.7 1.7 0.73 10.7 0.1 2.1 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Sin3_corepress PF08295.12 KHN68787.1 - 1.7e-16 60.1 2.0 2.9e-16 59.3 0.7 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 KHN68787.1 - 1.9e-14 53.5 8.1 7.2e-06 26.1 0.0 5.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 KHN68787.1 - 1.8e-13 50.9 11.7 2.2e-10 40.7 0.8 4.6 3 2 1 4 4 4 3 C-terminal domain of Sin3a protein She9_MDM33 PF05546.11 KHN68787.1 - 0.024 14.4 4.8 2.3 8.0 0.1 2.9 3 0 0 3 3 3 0 She9 / Mdm33 family DUF1160 PF06648.11 KHN68787.1 - 1.9 8.5 7.7 39 4.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1160) zf-SNAP50_C PF12251.8 KHN68788.1 - 7e-08 32.4 2.2 1.2e-07 31.6 2.2 1.6 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal SpvD PF05563.12 KHN68789.1 - 0.012 15.3 3.1 0.046 13.3 0.1 2.1 1 1 0 2 2 2 0 Salmonella plasmid virulence protein SpvD SPATA1_C PF15743.5 KHN68789.1 - 0.077 13.1 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus zf-C3HC4_5 PF17121.5 KHN68790.1 - 2.6e-16 59.3 7.8 5.1e-16 58.3 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MAT1 PF06391.13 KHN68790.1 - 3.1e-16 59.8 1.2 3.6e-16 59.6 1.2 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.6 KHN68790.1 - 4.4e-06 26.6 5.6 1e-05 25.4 5.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KHN68790.1 - 5.4e-06 26.2 7.0 5.4e-06 26.2 7.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KHN68790.1 - 1.5e-05 25.2 6.9 3.4e-05 24.1 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KHN68790.1 - 1.7e-05 24.5 7.0 4.9e-05 23.1 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KHN68790.1 - 3.4e-05 23.6 7.9 0.00014 21.6 7.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KHN68790.1 - 0.0018 18.3 7.3 0.0018 18.3 7.3 1.7 2 0 0 2 2 2 1 RING-type zinc-finger DNA_ligase_ZBD PF03119.16 KHN68790.1 - 0.007 16.4 1.0 3.3 7.8 0.1 2.5 2 0 0 2 2 2 2 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 KHN68790.1 - 0.031 14.3 4.3 0.16 12.0 4.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-UDP PF14569.6 KHN68790.1 - 0.038 14.1 3.2 0.069 13.3 3.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 KHN68790.1 - 0.052 13.3 14.8 0.3 10.9 11.9 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KHN68790.1 - 0.16 12.1 9.0 0.41 10.8 9.0 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 KHN68790.1 - 0.21 11.7 6.7 2.6 8.2 3.7 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_4 PF14447.6 KHN68790.1 - 0.22 11.4 10.2 8.9 6.3 10.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zinc_ribbon_2 PF13240.6 KHN68790.1 - 0.32 10.8 3.5 2.9 7.8 1.7 2.8 3 1 0 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.6 KHN68790.1 - 1 9.4 6.7 34 4.5 2.7 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_S21e PF01249.18 KHN68791.1 - 1.1e-11 44.7 0.1 1.2e-11 44.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e TIM PF00121.18 KHN68792.1 - 1.1e-72 244.3 0.0 1.3e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CRM1_C PF08767.11 KHN68793.1 - 1.6e-51 175.4 16.7 1.6e-51 175.4 16.7 3.4 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KHN68793.1 - 3.7e-31 108.2 4.1 3.7e-31 108.2 4.1 3.4 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 KHN68793.1 - 3.8e-23 81.3 6.7 1.1e-22 79.9 0.8 3.6 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 KHN68793.1 - 3.2e-21 74.7 0.3 3.2e-21 74.7 0.3 2.6 3 0 0 3 3 3 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 KHN68793.1 - 2.3e-09 37.0 0.5 9.6e-09 35.0 0.5 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 KHN68793.1 - 1.8e-07 30.6 0.2 5.6e-06 25.8 0.0 3.2 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat Tti2 PF10521.9 KHN68793.1 - 0.0037 16.8 6.4 0.37 10.3 0.8 3.0 2 1 1 3 3 3 2 Tti2 family DUF2779 PF11074.8 KHN68793.1 - 0.22 12.0 1.8 1.2 9.6 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) CoaE PF01121.20 KHN68794.1 - 1.1e-17 64.3 1.3 2.6e-09 37.0 0.1 2.1 1 1 1 2 2 2 2 Dephospho-CoA kinase AAA_28 PF13521.6 KHN68794.1 - 1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KHN68794.1 - 0.0013 19.3 0.2 0.002 18.6 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN68794.1 - 0.007 16.6 0.2 0.015 15.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KHN68794.1 - 0.013 15.4 0.8 0.034 14.0 0.8 1.8 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_24 PF13479.6 KHN68794.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KHN68794.1 - 0.045 13.5 0.2 0.065 12.9 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KHN68794.1 - 0.068 13.5 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KHN68794.1 - 0.075 13.5 0.3 0.18 12.3 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 KHN68794.1 - 0.08 13.4 0.5 3.7 8.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain cobW PF02492.19 KHN68794.1 - 0.087 12.4 0.2 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 KHN68794.1 - 0.12 11.3 0.2 0.15 10.9 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 KHN68794.1 - 0.15 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain A_thal_3526 PF09713.10 KHN68796.1 - 0.032 14.5 0.4 3.3 8.0 0.0 3.0 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) ABC_tran PF00005.27 KHN68797.1 - 4.6e-26 92.0 0.0 8.7e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KHN68797.1 - 7.7e-05 22.5 3.0 0.00015 21.6 3.0 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 KHN68797.1 - 0.0008 19.3 0.5 0.089 12.6 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KHN68797.1 - 0.0032 17.0 0.8 0.53 9.7 0.0 2.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KHN68797.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIN_4 PF13638.6 KHN68798.1 - 7.8e-11 42.4 2.1 1.4e-10 41.5 2.1 1.5 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 KHN68798.1 - 0.019 15.3 3.2 0.13 12.6 0.9 2.8 2 1 0 2 2 2 0 PIN like domain STAT_int PF02865.17 KHN68798.1 - 0.13 12.7 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 STAT protein, protein interaction domain zf-CHY PF05495.12 KHN68799.1 - 1e-16 61.2 23.8 1e-16 61.2 23.8 4.1 2 1 1 3 3 2 2 CHY zinc finger zf-RING_2 PF13639.6 KHN68799.1 - 8e-09 35.7 9.3 8e-09 35.7 9.3 5.4 3 1 2 5 5 2 1 Ring finger domain zinc_ribbon_6 PF14599.6 KHN68799.1 - 2.7e-08 33.7 0.6 2.7e-08 33.7 0.6 4.3 2 1 3 5 5 3 1 Zinc-ribbon zf-RING_5 PF14634.6 KHN68799.1 - 2.9e-06 27.1 9.4 2.9e-06 27.1 9.4 6.5 3 2 1 4 4 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KHN68799.1 - 3e-05 23.8 10.2 3e-05 23.8 10.2 6.0 4 2 2 6 6 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KHN68799.1 - 6.5e-05 22.7 7.9 6.5e-05 22.7 7.9 6.1 2 1 3 5 5 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KHN68799.1 - 0.00011 22.2 3.2 0.00011 22.2 3.2 5.3 3 3 3 6 6 5 1 RING-type zinc-finger zf-rbx1 PF12678.7 KHN68799.1 - 0.00045 20.4 7.2 0.00045 20.4 7.2 4.6 2 2 2 4 4 2 1 RING-H2 zinc finger domain Rubredoxin_2 PF18073.1 KHN68799.1 - 0.0016 18.1 0.2 0.0016 18.1 0.2 6.5 9 1 0 9 9 9 1 Rubredoxin metal binding domain Prok-RING_1 PF14446.6 KHN68799.1 - 0.0055 16.6 1.8 0.0055 16.6 1.8 6.4 3 2 4 7 7 7 1 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 KHN68799.1 - 0.62 10.5 0.1 0.62 10.5 0.1 6.2 3 2 0 3 3 2 0 Restriction alleviation protein Lar GDI PF00996.18 KHN68800.1 - 7.2e-09 34.7 0.5 0.002 16.7 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor DUF5625 PF18539.1 KHN68800.1 - 0.028 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5625) CagZ PF09053.10 KHN68800.1 - 0.042 13.5 0.4 0.1 12.2 0.1 1.7 2 0 0 2 2 2 0 CagZ Med31 PF05669.12 KHN68801.1 - 1.2e-29 102.2 3.3 1.4e-29 101.9 3.3 1.1 1 0 0 1 1 1 1 SOH1 Herpes_US9 PF06072.11 KHN68801.1 - 0.051 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RNA_pol_Rpb2_6 PF00562.28 KHN68802.1 - 1.4e-113 379.9 0.7 1.4e-113 379.9 0.7 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KHN68802.1 - 1.6e-46 158.4 1.2 2.5e-46 157.8 1.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KHN68802.1 - 9.6e-30 102.8 0.2 9.6e-30 102.8 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KHN68802.1 - 2.2e-20 73.1 0.5 4.3e-20 72.2 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KHN68802.1 - 2.9e-20 72.2 0.0 7.4e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KHN68802.1 - 1.2e-18 67.1 2.2 3.3e-18 65.7 2.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KHN68802.1 - 2.6e-11 43.9 0.0 6.6e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ubiquitin PF00240.23 KHN68803.1 - 1.8e-13 50.1 0.6 3.5e-13 49.1 0.6 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KHN68803.1 - 8.6e-05 22.3 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KHN68803.1 - 0.00056 20.4 0.2 0.00065 20.2 0.2 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KHN68803.1 - 0.013 15.5 0.7 0.12 12.5 0.4 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KHN68803.1 - 0.033 14.3 0.1 0.051 13.7 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FlgH PF02107.16 KHN68803.1 - 0.048 13.3 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 Flagellar L-ring protein Sec6 PF06046.13 KHN68804.1 - 1.5e-95 320.8 14.6 2.1e-95 320.3 14.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 PMC2NT PF08066.12 KHN68804.1 - 0.0086 16.7 4.1 3.9 8.2 0.1 4.0 4 0 0 4 4 4 2 PMC2NT (NUC016) domain Erv26 PF04148.13 KHN68805.1 - 9.3e-14 51.7 12.8 1.7e-12 47.6 12.8 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1440 PF07274.12 KHN68805.1 - 0.13 12.6 3.3 0.19 12.1 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) B5 PF03484.15 KHN68807.1 - 0.2 12.0 0.8 0.53 10.6 0.8 1.6 1 0 0 1 1 1 0 tRNA synthetase B5 domain Sel1 PF08238.12 KHN68808.1 - 1.3e-80 264.0 28.4 1.8e-08 34.8 0.5 13.2 13 0 0 13 13 13 13 Sel1 repeat TPR_6 PF13174.6 KHN68808.1 - 2.5e-06 27.8 3.5 0.58 10.9 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat NPCBM PF08305.11 KHN68808.1 - 0.0011 19.1 0.6 9.7 6.4 0.0 4.6 5 2 0 5 5 5 1 NPCBM/NEW2 domain TPR_17 PF13431.6 KHN68808.1 - 0.7 10.4 9.0 28 5.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RRM_1 PF00076.22 KHN68809.1 - 0.00012 21.8 0.1 0.00023 20.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.27 KHN68810.1 - 9e-35 120.7 0.0 2.1e-23 83.4 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KHN68810.1 - 3e-06 26.7 1.4 9.9e-06 25.1 1.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RGS PF00615.19 KHN68810.1 - 0.34 11.2 3.7 0.28 11.4 0.7 2.5 2 0 0 2 2 2 0 Regulator of G protein signaling domain Pescadillo_N PF06732.11 KHN68811.1 - 3e-22 79.5 5.7 6.1e-22 78.4 5.7 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 KHN68811.1 - 2.6e-07 31.0 0.0 5.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GIDA PF01134.22 KHN68811.1 - 0.066 12.3 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Kinesin PF00225.23 KHN68812.1 - 2.3e-74 250.3 4.1 3.6e-74 249.7 4.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KHN68812.1 - 1.5e-10 41.2 0.4 4.9e-10 39.5 0.4 1.9 1 0 0 1 1 1 1 Microtubule binding SAM_2 PF07647.17 KHN68812.1 - 0.00054 20.0 0.2 0.0015 18.6 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KHN68812.1 - 0.038 14.4 0.2 0.092 13.2 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Hjc PF01870.18 KHN68812.1 - 0.16 12.0 0.3 4.4 7.4 0.0 3.1 3 0 0 3 3 3 0 Archaeal holliday junction resolvase (hjc) CTP_synth_N PF06418.14 KHN68813.1 - 2e-46 158.4 0.2 3.3e-46 157.8 0.2 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KHN68813.1 - 3.5e-46 157.4 0.0 5.7e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KHN68813.1 - 1.6e-05 24.8 1.1 0.00062 19.6 1.1 2.6 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KHN68813.1 - 0.034 14.2 0.0 0.044 13.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1699 PF08004.11 KHN68814.1 - 0.03 14.0 3.2 0.04 13.6 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) DUF5402 PF17393.2 KHN68814.1 - 0.037 14.0 2.1 0.062 13.3 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5402) ABC_tran_CTD PF16326.5 KHN68814.1 - 0.045 14.0 7.2 0.038 14.2 4.3 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Occludin_ELL PF07303.13 KHN68814.1 - 0.13 13.0 3.5 0.16 12.7 0.6 2.6 2 0 0 2 2 2 0 Occludin homology domain DUF2203 PF09969.9 KHN68814.1 - 2.1 9.1 6.5 0.7 10.6 2.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) RRM_1 PF00076.22 KHN68815.1 - 2.3e-08 33.7 0.0 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_trans_1_2 PF13524.6 KHN68815.1 - 0.16 12.4 0.4 0.88 10.0 0.5 2.0 1 1 1 2 2 2 0 Glycosyl transferases group 1 BolA PF01722.18 KHN68816.1 - 5e-20 71.6 0.7 6.2e-20 71.3 0.7 1.1 1 0 0 1 1 1 1 BolA-like protein DNA_pol3_a_NII PF11490.8 KHN68816.1 - 0.013 15.4 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Polysacc_deac_1 PF01522.21 KHN68817.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide deacetylase Cyclin_N PF00134.23 KHN68818.1 - 6.4e-08 32.4 0.2 1.5e-07 31.2 0.1 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain tRNA-synt_1b PF00579.25 KHN68820.1 - 4e-23 82.2 0.0 2.2e-22 79.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HSP70 PF00012.20 KHN68821.1 - 8.8e-216 717.7 4.2 1e-215 717.5 4.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KHN68821.1 - 6.1e-19 68.0 2.3 4.6e-18 65.1 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KHN68821.1 - 0.00023 21.5 4.0 0.047 14.1 0.1 3.1 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 KHN68821.1 - 0.003 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ArfGap PF01412.18 KHN68822.1 - 2.7e-29 101.6 1.3 2.7e-29 101.6 1.3 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Cornichon PF03311.14 KHN68823.1 - 2.7e-06 27.7 1.0 3.2e-06 27.5 1.0 1.0 1 0 0 1 1 1 1 Cornichon protein JAB PF01398.21 KHN68824.1 - 9.6e-31 106.2 0.1 1.4e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KHN68824.1 - 8.5e-08 32.6 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KHN68824.1 - 3e-06 27.0 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KHN68824.1 - 0.031 14.3 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) NuA4 PF09340.10 KHN68826.1 - 6.2e-06 26.0 0.9 8.6e-06 25.5 0.9 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 TFR_dimer PF04253.15 KHN68826.1 - 0.13 12.3 0.9 0.21 11.7 0.9 1.5 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain RNA_pol_L_2 PF13656.6 KHN68827.1 - 1e-16 60.5 0.0 1.2e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CPSF_A PF03178.15 KHN68829.1 - 1.2e-55 189.1 0.9 2.2e-55 188.3 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region CDP-OH_P_transf PF01066.21 KHN68830.1 - 3.9e-15 56.4 1.3 3.9e-15 56.4 1.3 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase LSM PF01423.22 KHN68832.1 - 7.9e-09 35.1 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KHN68832.1 - 0.004 17.3 0.0 0.0054 16.8 0.0 1.2 1 0 0 1 1 1 1 RimP C-terminal SH3 domain Motile_Sperm PF00635.26 KHN68833.1 - 3e-21 75.3 0.2 4.3e-21 74.8 0.2 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF3271 PF11675.8 KHN68833.1 - 0.11 11.7 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Metallophos PF00149.28 KHN68834.1 - 1.4e-42 146.6 0.2 1.8e-42 146.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KHN68834.1 - 1.1e-14 54.6 0.2 2.4e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain eIF2A PF08662.11 KHN68835.1 - 1.2e-26 93.8 0.0 8.7e-26 91.0 0.0 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KHN68835.1 - 0.017 14.2 0.1 0.97 8.4 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region SRP_TPR_like PF17004.5 KHN68836.1 - 3.1e-37 127.2 3.2 3.1e-37 127.2 3.2 1.9 2 0 0 2 2 2 1 Putative TPR-like repeat ANAPC3 PF12895.7 KHN68836.1 - 6.1e-08 32.8 6.4 5.3e-06 26.6 2.9 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KHN68836.1 - 0.00086 19.2 7.4 0.25 11.6 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HTH_38 PF13936.6 KHN68836.1 - 0.011 15.5 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_1 PF00515.28 KHN68836.1 - 0.049 13.5 7.0 0.49 10.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KHN68836.1 - 0.11 12.9 0.6 3 8.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KHN68836.1 - 0.37 10.9 10.5 1.4 9.0 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 KHN68836.1 - 6.4 7.3 8.8 2.9 8.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NTP_transferase PF00483.23 KHN68837.1 - 1.7e-49 168.7 0.0 2e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KHN68837.1 - 2.9e-12 47.2 0.0 3.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 KHN68837.1 - 3.9e-06 26.4 12.7 0.0016 18.1 2.0 3.0 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KHN68837.1 - 0.0002 20.4 1.3 0.00078 18.5 0.5 2.0 2 1 1 3 3 3 1 L-fucokinase DUF4954 PF16314.5 KHN68837.1 - 0.0061 14.7 2.3 0.0095 14.1 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 KHN68837.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 KHN68837.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Hexapep_2 PF14602.6 KHN68837.1 - 0.77 9.6 10.6 1.5 8.6 5.0 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Pam16 PF03656.13 KHN68838.1 - 1e-07 32.0 0.1 1.6e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Pam16 Ribosomal_S10 PF00338.22 KHN68840.1 - 7e-10 39.0 0.4 9.5e-10 38.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SPO22 PF08631.10 KHN68840.1 - 0.006 16.1 0.1 0.007 15.9 0.1 1.0 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like CdiA_C PF18451.1 KHN68840.1 - 0.1 12.8 0.9 0.3 11.3 0.3 2.0 1 1 1 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain CBFD_NFYB_HMF PF00808.23 KHN68841.1 - 3.2e-12 46.5 0.4 5.3e-12 45.9 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone B2 PF11473.8 KHN68841.1 - 0.055 13.3 0.2 0.16 11.8 0.2 1.8 1 0 0 1 1 1 0 RNA binding protein B2 DUF4890 PF16231.5 KHN68841.1 - 0.085 13.3 2.6 0.2 12.2 0.4 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4890) Syntaxin PF00804.25 KHN68842.1 - 0.055 13.1 3.5 0.068 12.8 3.5 1.1 1 0 0 1 1 1 0 Syntaxin NPR1_interact PF15699.5 KHN68842.1 - 0.081 13.6 1.3 0.1 13.2 1.3 1.1 1 0 0 1 1 1 0 NPR1 interacting KH_8 PF17903.1 KHN68843.1 - 4.7e-06 26.6 0.3 9.6e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KHN68843.1 - 0.00013 21.7 1.9 0.00013 21.7 1.9 1.8 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 KHN68843.1 - 0.015 15.2 0.4 0.047 13.6 0.1 2.0 2 0 0 2 2 2 0 KH domain XPG_I PF00867.18 KHN68844.1 - 8.3e-17 61.3 0.3 5e-16 58.8 0.1 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KHN68844.1 - 7e-16 58.6 0.0 1.7e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KHN68844.1 - 0.00057 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.9 KHN68844.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda LRR_8 PF13855.6 KHN68845.1 - 5.5e-16 58.1 20.6 1.9e-10 40.3 3.0 2.7 1 1 2 3 3 3 3 Leucine rich repeat Exo_endo_phos PF03372.23 KHN68845.1 - 9.4e-16 58.0 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 KHN68845.1 - 1e-12 48.0 10.1 4.5e-06 26.9 0.4 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KHN68845.1 - 0.00048 20.3 7.4 5.1 8.1 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 KHN68845.1 - 0.0041 17.1 11.7 0.47 10.6 0.2 4.0 4 0 0 4 4 4 3 Leucine Rich repeat Ribosomal_S7e PF01251.18 KHN68846.1 - 0.082 12.7 0.5 0.19 11.4 0.5 1.6 1 1 0 1 1 1 0 Ribosomal protein S7e Sec23_trunk PF04811.15 KHN68847.1 - 8.8e-36 123.7 0.0 1.8e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KHN68847.1 - 1.4e-16 60.1 0.2 2.4e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KHN68847.1 - 2.4e-14 53.8 0.1 5.2e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KHN68847.1 - 1.2e-10 41.2 6.5 3.4e-10 39.8 6.5 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KHN68847.1 - 0.00019 21.3 0.0 0.001 18.9 0.0 2.1 1 1 0 1 1 1 1 Gelsolin repeat MCM PF00493.23 KHN68848.1 - 1.3e-71 240.2 0.0 1.9e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 KHN68848.1 - 1.7e-19 70.0 0.7 3.6e-19 69.0 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 KHN68848.1 - 2.3e-17 63.0 0.5 4.2e-17 62.2 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 KHN68848.1 - 1.5e-07 31.5 0.0 4.1e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KHN68848.1 - 4.4e-06 26.2 0.1 0.00041 19.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KHN68848.1 - 0.0023 17.5 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 KHN68848.1 - 0.016 15.0 0.1 0.064 13.0 0.1 1.9 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Nif11 PF07862.11 KHN68848.1 - 0.018 15.3 0.1 0.93 9.9 0.0 3.2 4 0 0 4 4 4 0 Nif11 domain AsiA PF09010.10 KHN68848.1 - 0.022 14.8 1.0 2.8 8.1 0.1 2.6 2 0 0 2 2 2 0 Anti-Sigma Factor A Sigma54_activat PF00158.26 KHN68848.1 - 0.054 13.2 0.0 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 KHN68848.1 - 0.065 13.1 0.0 0.49 10.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KHN68848.1 - 0.26 11.7 0.9 0.67 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Ribosomal_S8e PF01201.22 KHN68849.1 - 3.2e-39 134.2 1.6 7.8e-39 133.0 1.4 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Bud13 PF09736.9 KHN68849.1 - 1.8 9.0 10.4 3.1 8.2 10.4 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Rad51 PF08423.11 KHN68850.1 - 7.1e-126 418.7 0.0 9.2e-126 418.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KHN68850.1 - 1.6e-09 37.6 0.1 2.2e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KHN68850.1 - 1.1e-06 28.2 0.1 1.6e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KHN68850.1 - 2.9e-06 27.8 0.4 6.7e-06 26.6 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 KHN68850.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN68850.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN68850.1 - 0.034 13.9 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TFIID_30kDa PF03540.13 KHN68851.1 - 9.8e-20 70.3 0.0 1.7e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 KHN68851.1 - 0.02 14.9 0.1 0.11 12.5 0.0 2.2 1 1 1 2 2 2 0 Bromodomain associated AAA PF00004.29 KHN68852.1 - 1.1e-26 93.8 0.2 6.9e-26 91.2 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KHN68852.1 - 8.2e-05 22.6 0.1 0.0014 18.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KHN68852.1 - 0.00012 22.3 0.1 0.00012 22.3 0.1 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 KHN68852.1 - 0.00023 21.1 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.6 KHN68852.1 - 0.00052 20.3 0.0 0.0017 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KHN68852.1 - 0.00055 19.5 1.6 0.00091 18.8 0.8 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 KHN68852.1 - 0.0024 17.6 0.2 0.007 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KHN68852.1 - 0.0026 17.6 2.7 0.0035 17.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KHN68852.1 - 0.0048 17.1 0.2 0.018 15.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KHN68852.1 - 0.02 14.7 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 KHN68852.1 - 0.023 15.1 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KHN68852.1 - 0.029 14.8 0.1 0.17 12.3 0.0 2.4 1 1 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KHN68852.1 - 0.031 14.2 0.6 0.061 13.2 0.6 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ResIII PF04851.15 KHN68852.1 - 0.034 14.1 2.2 0.27 11.2 2.2 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KHN68852.1 - 0.043 14.2 0.0 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KHN68852.1 - 0.043 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KHN68852.1 - 0.046 13.4 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KHN68852.1 - 0.081 12.8 0.1 0.78 9.6 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) SARAF PF06682.12 KHN68852.1 - 0.087 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TsaE PF02367.17 KHN68852.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KHN68852.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 KHN68852.1 - 0.23 10.8 5.8 3.7 6.9 0.3 3.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit HA2 PF04408.23 KHN68853.1 - 1.3e-16 60.8 0.1 3.1e-16 59.6 0.1 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KHN68853.1 - 3.7e-13 49.8 0.1 1.6e-12 47.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KHN68853.1 - 5.4e-10 39.3 0.9 9.7e-10 38.5 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KHN68853.1 - 8.1e-08 32.5 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KHN68853.1 - 6.3e-06 26.6 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KHN68853.1 - 1.9e-05 24.7 0.4 0.00027 21.0 0.4 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KHN68853.1 - 4.7e-05 23.7 0.2 0.00014 22.1 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KHN68853.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KHN68853.1 - 0.0025 16.9 0.0 0.0054 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KHN68853.1 - 0.0052 16.8 2.1 0.097 12.7 2.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KHN68853.1 - 0.0077 16.0 2.0 0.33 10.7 0.0 3.2 4 0 0 4 4 4 1 AAA domain SRP54 PF00448.22 KHN68853.1 - 0.0093 15.6 0.4 0.025 14.2 0.4 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain DUF2075 PF09848.9 KHN68853.1 - 0.011 15.0 1.0 0.027 13.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KHN68853.1 - 0.019 14.3 4.2 0.027 13.8 0.7 2.6 2 1 0 2 2 2 0 KaiC Flavi_DEAD PF07652.14 KHN68853.1 - 0.04 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain RsgA_GTPase PF03193.16 KHN68853.1 - 0.061 13.2 0.2 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 KHN68853.1 - 0.07 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Intron_maturas2 PF01348.21 KHN68853.1 - 0.11 12.4 2.3 0.92 9.5 0.4 2.5 2 0 0 2 2 2 0 Type II intron maturase ATPase_2 PF01637.18 KHN68853.1 - 0.96 9.3 6.8 0.69 9.8 1.1 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea CTP_transf_like PF01467.26 KHN68854.1 - 5.3e-41 140.2 0.1 3.8e-23 82.3 0.0 2.1 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 KHN68854.1 - 0.00038 20.4 0.9 1.7 8.5 0.0 3.4 2 1 0 2 2 2 2 FAD synthetase tRNA-synt_1g PF09334.11 KHN68855.1 - 1.1e-137 458.9 0.1 1.4e-137 458.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KHN68855.1 - 4.8e-08 31.7 1.1 2.4e-06 26.1 0.1 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) zf-CHY PF05495.12 KHN68855.1 - 2.1 8.9 9.1 25 5.4 9.1 2.5 1 1 1 2 2 2 0 CHY zinc finger HEAT_2 PF13646.6 KHN68856.1 - 3.3e-05 24.2 0.0 0.047 14.1 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KHN68856.1 - 0.0036 17.4 9.1 10 6.7 0.1 7.5 8 0 0 8 8 8 2 HEAT repeat SF3b1 PF08920.10 KHN68856.1 - 0.018 15.5 0.4 0.035 14.6 0.4 1.4 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 Utp14 PF04615.13 KHN68857.1 - 2.2e-39 135.7 29.4 4.8e-36 124.7 6.0 3.0 1 1 2 3 3 3 3 Utp14 protein P63C PF10546.9 KHN68857.1 - 0.015 15.9 0.4 0.084 13.5 0.3 2.3 2 0 0 2 2 2 0 P63C domain GyrB_insert PF18053.1 KHN68857.1 - 0.094 12.6 1.1 0.38 10.6 1.5 1.8 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain EIF_2_alpha PF07541.12 KHN68859.1 - 2.5e-16 59.8 0.1 5.3e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KHN68859.1 - 4.1e-10 39.9 0.5 1.4e-09 38.2 0.2 2.0 2 1 0 2 2 2 1 S1 RNA binding domain Ribosomal_L7Ae PF01248.26 KHN68861.1 - 4.4e-11 42.4 0.1 6.5e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KHN68861.1 - 0.0037 17.3 0.0 0.004 17.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Pkinase PF00069.25 KHN68863.1 - 5.6e-69 232.4 0.1 6.5e-69 232.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN68863.1 - 3.3e-39 134.7 0.2 4.3e-39 134.4 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KHN68863.1 - 5.9e-08 32.1 0.2 1.1e-07 31.1 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KHN68863.1 - 1.3e-06 27.9 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KHN68863.1 - 7e-05 22.3 0.3 0.00014 21.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KHN68863.1 - 0.00021 21.0 0.2 0.18 11.4 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KHN68863.1 - 0.0011 18.6 0.2 0.002 17.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KHN68863.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DCP1 PF06058.13 KHN68864.1 - 1.5e-20 73.2 0.0 1.8e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Synaptobrevin PF00957.21 KHN68865.1 - 5.6e-06 26.1 1.3 5.6e-06 26.1 1.3 1.8 2 0 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 KHN68865.1 - 0.0046 16.9 0.9 0.041 13.8 0.2 2.2 2 0 0 2 2 2 1 Sec20 Longin PF13774.6 KHN68865.1 - 0.014 15.4 0.1 0.026 14.6 0.1 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF16 PF01519.16 KHN68865.1 - 0.08 13.4 0.1 0.51 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-C2H2_4 PF13894.6 KHN68866.1 - 6.6e-06 26.5 4.2 0.008 16.9 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KHN68866.1 - 5.8e-05 23.0 2.1 0.25 11.4 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KHN68866.1 - 0.00015 22.1 3.8 0.024 15.1 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_9 PF16293.5 KHN68866.1 - 0.002 17.9 1.7 0.087 12.7 0.3 2.7 3 0 0 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 KHN68866.1 - 0.0039 17.5 2.0 0.0068 16.7 2.0 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF2256 PF10013.9 KHN68866.1 - 0.0062 16.6 1.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2256) Mesd PF10185.9 KHN68866.1 - 0.02 14.8 2.2 0.38 10.7 0.3 2.1 2 0 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor zf-C2H2_jaz PF12171.8 KHN68866.1 - 0.022 15.1 2.3 1.2 9.6 0.3 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.12 KHN68866.1 - 0.038 14.5 4.4 0.038 14.5 4.4 1.7 2 0 0 2 2 2 0 CHY zinc finger zf-C2H2_3rep PF18868.1 KHN68866.1 - 0.053 14.2 1.4 0.053 14.2 1.4 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 KHN68866.1 - 0.11 12.1 2.1 8.6 6.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 KHN68866.1 - 0.49 10.5 4.5 0.48 10.6 2.5 2.1 2 1 0 2 2 2 0 Zinc ribbon domain Mut7-C PF01927.16 KHN68866.1 - 0.75 9.9 5.7 0.19 11.8 2.0 1.8 2 0 0 2 2 2 0 Mut7-C RNAse domain zf-H2C2_2 PF13465.6 KHN68866.1 - 2.1 8.9 7.2 3.5 8.2 0.5 2.9 2 1 0 2 2 2 0 Zinc-finger double domain C1_2 PF03107.16 KHN68866.1 - 3.6 8.0 6.7 16 5.9 0.4 2.4 1 1 1 2 2 2 0 C1 domain zf-RING_2 PF13639.6 KHN68867.1 - 1.1e-11 44.9 6.1 1.7e-11 44.3 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KHN68867.1 - 7.3e-11 41.7 5.9 1.1e-10 41.2 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KHN68867.1 - 6.3e-10 38.8 4.9 1.1e-09 37.9 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KHN68867.1 - 9.7e-10 38.6 6.2 1.6e-09 37.9 6.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KHN68867.1 - 1.2e-09 37.8 4.2 1.8e-09 37.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KHN68867.1 - 5.2e-07 29.5 7.0 7.7e-07 29.0 7.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KHN68867.1 - 8.6e-07 28.6 4.0 2.4e-06 27.2 4.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KHN68867.1 - 1.3e-06 28.3 1.4 2.7e-06 27.3 1.4 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KHN68867.1 - 2.6e-05 24.2 6.0 5.8e-05 23.1 6.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KHN68867.1 - 0.0004 20.1 3.4 0.00076 19.2 3.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 KHN68867.1 - 0.002 18.3 3.4 0.19 12.1 0.6 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 KHN68867.1 - 0.004 17.0 5.7 0.017 15.0 5.6 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KHN68867.1 - 0.0046 16.5 6.5 0.011 15.3 6.4 1.7 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KHN68867.1 - 0.0068 16.5 7.7 0.044 14.0 6.5 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KHN68867.1 - 0.042 14.0 9.1 3.8 7.7 9.1 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KHN68867.1 - 0.087 13.1 7.8 0.4 11.0 8.0 1.9 1 1 1 2 2 2 0 RING-like domain RINGv PF12906.7 KHN68867.1 - 0.13 12.4 6.5 0.58 10.3 6.4 2.0 1 1 1 2 2 2 0 RING-variant domain Fibrillin_U_N PF18193.1 KHN68867.1 - 0.19 11.9 1.6 0.32 11.2 1.6 1.4 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain zinc_ribbon_9 PF14369.6 KHN68867.1 - 0.25 11.6 4.7 1.4 9.2 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon PHD PF00628.29 KHN68867.1 - 0.28 11.1 7.5 0.98 9.4 7.5 2.0 1 1 0 1 1 1 0 PHD-finger UPF0547 PF10571.9 KHN68867.1 - 6.3 7.0 9.6 2.5 8.3 0.1 3.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 LsmAD PF06741.13 KHN68869.1 - 2.5e-15 56.8 1.0 6.3e-15 55.5 1.0 1.7 1 0 0 1 1 1 1 LsmAD domain AAA PF00004.29 KHN68870.1 - 1.5e-39 135.4 0.0 2.7e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN68870.1 - 3.2e-12 46.1 0.0 1.4e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 KHN68870.1 - 3.5e-08 33.3 0.1 1e-07 31.8 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 KHN68870.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KHN68870.1 - 0.00015 21.8 0.1 0.0011 19.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KHN68870.1 - 0.00028 21.2 1.0 0.02 15.2 0.9 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KHN68870.1 - 0.00096 19.6 0.7 0.041 14.3 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KHN68870.1 - 0.0019 18.3 0.0 0.0098 16.0 0.0 2.1 1 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 KHN68870.1 - 0.0026 17.2 0.1 2 7.8 0.0 2.7 1 1 1 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 KHN68870.1 - 0.0084 15.5 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KHN68870.1 - 0.01 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KHN68870.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_21 PF13304.6 KHN68870.1 - 0.03 14.2 0.4 0.69 9.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KHN68870.1 - 0.046 13.3 0.1 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KHN68870.1 - 0.099 12.7 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KHN68870.1 - 0.1 11.9 0.6 10 5.4 0.2 2.3 1 1 1 2 2 2 0 KaiC IstB_IS21 PF01695.17 KHN68870.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KHN68870.1 - 0.13 12.8 0.1 0.4 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN68870.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KHN68870.1 - 0.17 11.4 0.1 0.46 10.0 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KHN68870.1 - 0.17 12.3 0.0 1.1 9.7 0.0 2.3 2 1 0 2 2 2 0 RNA helicase PTR2 PF00854.21 KHN68872.1 - 5.6e-84 282.3 18.3 8.1e-84 281.7 18.3 1.2 1 0 0 1 1 1 1 POT family DUF3179 PF11376.8 KHN68872.1 - 0.24 10.7 0.2 0.41 10.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) BCCT PF02028.17 KHN68873.1 - 0.019 13.4 2.8 0.029 12.8 2.8 1.4 1 1 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter adh_short PF00106.25 KHN68874.1 - 3.5e-20 72.3 0.0 6.4e-19 68.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KHN68874.1 - 2.1e-12 47.1 0.0 8.7e-12 45.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KHN68874.1 - 9e-08 31.9 0.0 1.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KHN68874.1 - 3.1e-06 27.2 0.1 5.5e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 KHN68874.1 - 0.00015 21.8 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KHN68874.1 - 0.0016 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KHN68874.1 - 0.0019 17.9 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox PF00070.27 KHN68874.1 - 0.021 15.4 0.1 0.21 12.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 KHN68874.1 - 0.032 14.2 0.0 0.089 12.8 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 KHN68874.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Helicase_RecD PF05127.14 KHN68874.1 - 0.091 12.6 0.1 0.73 9.7 0.0 2.0 2 0 0 2 2 2 0 Helicase NAD_binding_10 PF13460.6 KHN68874.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Sod_Fe_C PF02777.18 KHN68875.1 - 6.5e-35 119.4 2.2 1.2e-34 118.6 0.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KHN68875.1 - 1.6e-26 92.6 0.6 3.1e-26 91.7 0.6 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Erf4 PF10256.9 KHN68876.1 - 9.4e-06 25.7 0.0 1.5e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family tRNA-synt_1 PF00133.22 KHN68877.1 - 3.4e-195 649.8 0.0 5.9e-166 553.2 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KHN68877.1 - 8.6e-24 84.2 0.1 3.2e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KHN68877.1 - 7.5e-13 48.0 0.0 0.0005 18.9 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KHN68877.1 - 0.005 16.2 0.1 0.11 11.8 0.0 3.0 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain VAPB_antitox PF02697.14 KHN68878.1 - 0.054 14.3 4.1 0.22 12.3 1.5 3.1 2 1 0 2 2 2 0 Putative antitoxin NepR PF18557.1 KHN68878.1 - 0.068 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma factor NepR Spc7 PF08317.11 KHN68878.1 - 0.14 11.0 28.8 2 7.2 1.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KHN68878.1 - 0.14 12.2 29.5 0.88 9.6 11.1 4.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 KHN68878.1 - 0.26 11.0 33.0 0.21 11.2 21.9 3.4 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 KHN68878.1 - 0.65 10.5 13.3 1.6 9.2 3.4 3.4 1 1 2 3 3 3 0 Type III cell invasion protein SipB Cnn_1N PF07989.11 KHN68878.1 - 0.67 10.2 19.1 6.2 7.0 0.1 4.1 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 GAS PF13851.6 KHN68878.1 - 2.5 7.4 30.6 5.8 6.2 23.0 3.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sulfatase_C PF14707.6 KHN68878.1 - 2.8 8.7 8.6 0.97 10.2 1.3 3.2 2 2 0 3 3 3 0 C-terminal region of aryl-sulfatase DNA_pack_N PF02500.15 KHN68878.1 - 3.5 7.4 7.7 1.2 8.9 2.6 2.3 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus TACC_C PF05010.14 KHN68878.1 - 4.3 7.1 30.5 0.97 9.2 19.7 3.0 1 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DivIC PF04977.15 KHN68878.1 - 6.8 6.5 25.2 0.028 14.2 3.5 4.9 4 1 0 5 5 5 0 Septum formation initiator GTP_EFTU PF00009.27 KHN68879.1 - 1.8e-31 109.2 0.2 2.7e-31 108.6 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KHN68879.1 - 7.1e-09 35.6 0.2 1.7e-07 31.2 0.1 2.8 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KHN68879.1 - 0.00038 20.5 0.1 0.0014 18.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.6 KHN68880.1 - 6.7e-08 32.3 7.5 1.2e-07 31.4 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KHN68880.1 - 3.3e-07 30.1 4.6 8.2e-07 28.8 4.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KHN68880.1 - 4.5e-07 30.1 11.1 4.5e-07 30.1 11.1 1.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KHN68880.1 - 3.3e-06 27.0 5.2 3.3e-06 27.0 5.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KHN68880.1 - 3.5e-06 26.8 8.2 6.1e-06 26.0 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KHN68880.1 - 2.4e-05 24.2 8.1 2.4e-05 24.2 8.1 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KHN68880.1 - 0.00013 22.1 9.6 0.00039 20.5 9.6 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KHN68880.1 - 0.00015 21.5 9.2 0.00043 20.1 9.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KHN68880.1 - 0.0021 18.3 7.0 0.0047 17.2 7.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KHN68880.1 - 0.0049 16.9 4.5 0.0086 16.1 4.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 KHN68880.1 - 0.093 12.9 7.9 0.15 12.2 7.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 HscB_4_cys PF18256.1 KHN68880.1 - 0.69 9.8 14.0 0.78 9.6 9.9 2.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif DiS_P_DiS PF06750.13 KHN68880.1 - 1.4 9.1 8.1 0.26 11.4 4.3 1.8 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain ORMDL PF04061.14 KHN68881.1 - 1.3e-28 99.5 5.9 1.5e-28 99.3 5.9 1.0 1 0 0 1 1 1 1 ORMDL family TPR_1 PF00515.28 KHN68882.1 - 1.2e-20 72.4 17.5 0.0015 18.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KHN68882.1 - 1.8e-19 68.2 12.6 0.014 15.4 0.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KHN68882.1 - 1.2e-14 53.2 0.7 0.0012 18.7 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KHN68882.1 - 1.6e-14 52.8 11.9 0.026 14.7 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KHN68882.1 - 9.8e-10 38.8 0.0 0.012 16.1 0.0 5.7 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KHN68882.1 - 3.8e-09 36.6 0.0 1.3 10.1 0.0 6.8 5 1 3 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KHN68882.1 - 1e-07 32.2 7.2 0.042 14.1 0.1 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KHN68882.1 - 1.8e-07 31.3 6.2 0.003 17.7 0.0 4.2 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KHN68882.1 - 8.3e-07 28.7 1.6 10 6.1 0.0 6.6 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KHN68882.1 - 3.4e-06 27.3 1.7 11 6.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KHN68882.1 - 4.9e-06 27.1 0.0 0.00023 21.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KHN68882.1 - 0.0082 16.5 3.1 1.2 9.7 0.0 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KHN68882.1 - 0.019 14.2 0.0 17 4.5 0.0 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KHN68882.1 - 0.022 14.4 5.7 4.7 7.0 0.0 5.8 5 1 2 7 7 7 0 TPR repeat Fis1_TPR_C PF14853.6 KHN68882.1 - 0.045 13.8 7.9 3.8 7.7 0.1 4.3 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 KHN68882.1 - 0.05 13.8 0.0 1.9 8.7 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 KHN68882.1 - 0.13 12.6 0.0 2.6 8.4 0.0 2.9 4 1 0 4 4 2 0 Tetratricopeptide repeat UTP15_C PF09384.10 KHN68883.1 - 5.8e-09 35.8 0.0 9.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KHN68883.1 - 1.3e-06 29.0 0.2 0.8 10.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Speriolin_C PF15059.6 KHN68883.1 - 0.0021 18.2 0.2 0.007 16.5 0.2 1.9 1 0 0 1 1 1 1 Speriolin C-terminus PQQ_3 PF13570.6 KHN68883.1 - 0.014 15.9 3.4 1.7 9.2 0.6 3.6 4 0 0 4 4 4 0 PQQ-like domain DivIC PF04977.15 KHN68883.1 - 0.18 11.6 3.5 0.56 10.0 3.5 1.9 1 1 0 1 1 1 0 Septum formation initiator ParA PF10609.9 KHN68884.1 - 4.7e-69 232.6 0.9 5.7e-69 232.3 0.9 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KHN68884.1 - 1.4e-12 47.8 0.1 5.7e-09 36.1 0.0 2.3 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KHN68884.1 - 1.4e-09 38.1 0.3 2.7e-09 37.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KHN68884.1 - 2.4e-06 27.0 0.9 9.9e-05 21.7 0.1 2.6 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KHN68884.1 - 0.00031 20.1 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 KHN68884.1 - 0.0018 17.8 0.2 0.0083 15.6 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 KHN68884.1 - 0.0027 17.5 0.1 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 KHN68884.1 - 0.0035 17.3 0.1 0.068 13.1 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase NB-ARC PF00931.22 KHN68884.1 - 0.0073 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.20 KHN68884.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 KHN68884.1 - 0.042 13.7 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zn-ribbon_8 PF09723.10 KHN68884.1 - 0.042 14.0 1.4 0.042 14.0 1.4 2.4 2 1 0 2 2 2 0 Zinc ribbon domain NTPase_1 PF03266.15 KHN68884.1 - 0.07 13.0 0.1 0.07 13.0 0.1 1.9 3 0 0 3 3 2 0 NTPase SRP54 PF00448.22 KHN68884.1 - 0.074 12.7 0.5 2 8.0 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KHN68884.1 - 0.097 13.2 0.1 0.17 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain OrfB_Zn_ribbon PF07282.11 KHN68884.1 - 0.13 12.2 1.2 0.32 10.9 1.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain MeaB PF03308.16 KHN68884.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KHN68884.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DUF1451 PF07295.11 KHN68884.1 - 3.7 7.6 5.2 1.1 9.3 1.5 2.0 3 0 0 3 3 3 0 Zinc-ribbon containing domain ABC_tran PF00005.27 KHN68885.1 - 1.2e-29 103.5 0.0 2.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KHN68885.1 - 2.8e-21 76.4 12.6 4.2e-21 75.8 12.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 KHN68885.1 - 2.3e-10 40.8 1.7 0.00042 20.2 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KHN68885.1 - 6.5e-06 25.7 5.1 9.9e-05 21.9 1.9 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KHN68885.1 - 0.00018 21.2 0.1 0.0007 19.3 0.1 2.0 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KHN68885.1 - 0.00018 21.3 0.1 0.00044 20.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 KHN68885.1 - 0.00064 18.5 0.3 0.054 12.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KHN68885.1 - 0.0028 18.0 0.1 0.0094 16.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 KHN68885.1 - 0.0041 16.7 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KHN68885.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KHN68885.1 - 0.024 15.0 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 KHN68885.1 - 0.026 14.6 0.1 0.068 13.2 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 KHN68885.1 - 0.027 14.1 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 KHN68885.1 - 0.029 14.9 0.1 0.055 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KHN68885.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KHN68885.1 - 0.04 13.8 0.2 12 5.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.6 KHN68885.1 - 0.049 14.2 0.9 0.084 13.4 0.2 1.9 2 1 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 KHN68885.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 KHN68885.1 - 0.051 12.7 0.1 0.085 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 KHN68885.1 - 0.067 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PulG PF11773.8 KHN68885.1 - 0.072 12.9 0.4 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin AAA_22 PF13401.6 KHN68885.1 - 0.082 13.2 0.3 0.54 10.5 0.3 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KHN68885.1 - 0.097 12.6 0.2 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KHN68885.1 - 0.13 12.3 0.8 0.26 11.3 0.8 1.5 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 KHN68885.1 - 0.16 12.4 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3742 PF12553.8 KHN68885.1 - 0.39 10.8 6.5 0.17 12.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) DUF5571 PF17732.1 KHN68886.1 - 0.14 11.6 1.3 0.25 10.8 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5571) Spindle_Spc25 PF08234.12 KHN68888.1 - 3.1e-08 33.7 0.2 3.1e-08 33.7 0.2 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Bacillus_HBL PF05791.11 KHN68888.1 - 0.0021 17.9 0.2 0.0029 17.4 0.2 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF3450 PF11932.8 KHN68888.1 - 0.046 13.0 4.6 0.079 12.3 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 KHN68888.1 - 0.2 11.5 12.5 0.36 10.6 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TEX13 PF15186.6 KHN68888.1 - 2.9 7.6 10.5 6.2 6.5 0.9 2.3 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family XendoU PF09412.10 KHN68889.1 - 0.046 12.9 1.1 0.074 12.3 1.1 1.4 1 0 0 1 1 1 0 Endoribonuclease XendoU Drc1-Sld2 PF11719.8 KHN68889.1 - 0.3 10.6 6.6 0.53 9.8 6.6 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein TAF8_C PF10406.9 KHN68890.1 - 2.5e-10 40.8 0.0 4.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KHN68890.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Filo_VP35 PF02097.15 KHN68890.1 - 0.072 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 MutL_C PF08676.11 KHN68891.1 - 5.3e-26 91.1 0.0 8.9e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KHN68891.1 - 3.9e-07 29.8 0.0 8.9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KHN68891.1 - 1.4e-05 24.9 0.2 4.2e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KHN68891.1 - 0.00085 19.8 0.0 0.0021 18.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ldh_1_C PF02866.18 KHN68891.1 - 0.11 12.4 0.3 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain TIP49 PF06068.13 KHN68892.1 - 4.3e-118 394.5 7.6 1.3e-117 392.9 7.6 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KHN68892.1 - 3.5e-17 62.3 0.9 6.8e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KHN68892.1 - 1.8e-06 28.4 0.7 0.00046 20.6 0.3 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KHN68892.1 - 5.7e-05 23.4 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KHN68892.1 - 7.7e-05 22.5 0.3 0.077 12.7 0.2 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 KHN68892.1 - 0.00017 21.4 0.8 0.52 10.0 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KHN68892.1 - 0.0013 19.1 0.5 0.0085 16.5 0.3 2.1 2 1 0 2 2 2 1 AAA ATPase domain TsaE PF02367.17 KHN68892.1 - 0.0014 18.6 0.1 0.0066 16.4 0.3 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KHN68892.1 - 0.0031 17.3 0.4 0.86 9.3 0.3 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KHN68892.1 - 0.0033 16.8 1.6 0.1 12.0 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KHN68892.1 - 0.01 15.8 0.6 2.3 8.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 KHN68892.1 - 0.022 14.0 0.1 0.03 13.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KHN68892.1 - 0.073 13.4 1.2 0.98 9.8 1.2 2.2 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KHN68892.1 - 0.18 11.8 0.5 4.2 7.3 0.2 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.25 KHN68893.1 - 3.9e-108 360.0 0.0 5.5e-108 359.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KHN68893.1 - 4.1e-43 146.1 0.0 7.9e-43 145.2 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KHN68893.1 - 4e-11 43.3 1.3 4e-11 43.3 1.3 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Pkinase PF00069.25 KHN68894.1 - 5e-63 212.9 0.0 5.9e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN68894.1 - 4.3e-31 108.1 0.0 6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN68894.1 - 0.00023 20.6 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KHN68894.1 - 0.0022 17.6 0.1 0.004 16.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KHN68894.1 - 0.012 14.9 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KHN68894.1 - 0.11 11.4 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pyr_redox_2 PF07992.14 KHN68896.1 - 8.1e-14 51.5 0.8 7.1e-10 38.6 0.3 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KHN68896.1 - 6.5e-09 35.5 1.2 0.051 12.8 0.1 3.3 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KHN68896.1 - 1.2e-08 33.9 0.2 0.0032 16.0 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KHN68896.1 - 6.1e-07 29.6 0.1 1.4e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KHN68896.1 - 1.9e-06 27.4 0.1 7.5e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 KHN68896.1 - 8.4e-06 25.3 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KHN68896.1 - 6.2e-05 21.9 0.1 0.00025 19.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KHN68896.1 - 7.3e-05 22.5 0.1 0.0055 16.3 0.2 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KHN68896.1 - 0.00011 21.4 0.1 0.00025 20.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KHN68896.1 - 0.00054 19.4 0.1 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KHN68896.1 - 0.0023 18.5 1.9 0.43 11.2 0.1 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KHN68896.1 - 0.0037 17.3 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 KHN68896.1 - 0.0082 15.3 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KHN68896.1 - 0.018 15.5 0.3 1.5 9.3 0.0 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KHN68896.1 - 0.039 13.2 0.3 0.083 12.1 0.1 1.6 2 0 0 2 2 2 0 Thi4 family TRAPP PF04051.16 KHN68897.1 - 3.7e-17 62.4 0.0 9.5e-17 61.1 0.0 1.6 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component Forkhead PF00250.18 KHN68898.1 - 2.9e-33 114.0 0.3 5.1e-33 113.2 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain ABC_tran PF00005.27 KHN68899.1 - 6.2e-19 68.9 0.0 6.2e-19 68.9 0.0 3.5 3 1 0 3 3 3 1 ABC transporter SMC_N PF02463.19 KHN68899.1 - 0.0065 15.9 0.1 0.0065 15.9 0.1 3.7 3 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 KHN68899.1 - 0.025 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Cas_APE2256 PF09651.10 KHN68899.1 - 0.036 13.9 2.8 0.16 11.9 0.2 3.5 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_APE2256) AAA_29 PF13555.6 KHN68899.1 - 0.037 13.8 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KHN68899.1 - 0.19 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Shisa PF13908.6 KHN68899.1 - 2.8 8.1 4.3 0.7 10.1 0.3 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2325 PF10087.9 KHN68899.1 - 6.9 6.9 7.5 29 4.9 0.1 4.8 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2325) IF4E PF01652.18 KHN68900.1 - 3.5e-24 85.4 0.3 4.1e-24 85.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Lectin_C PF00059.21 KHN68900.1 - 0.044 14.5 0.2 0.93 10.3 0.1 2.2 2 0 0 2 2 2 0 Lectin C-type domain dsDNA_bind PF01984.20 KHN68901.1 - 0.002 18.4 0.2 0.002 18.4 0.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain CNOT1_HEAT PF16418.5 KHN68902.1 - 2e-15 57.2 0.9 7.4e-15 55.3 0.1 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_CAF1_bind PF16415.5 KHN68902.1 - 1.1e-14 54.4 0.0 7.6e-14 51.6 0.0 2.5 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KHN68902.1 - 1e-10 41.7 0.5 3.2e-10 40.1 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KHN68902.1 - 7.7e-10 38.3 0.8 7.7e-10 38.3 0.8 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain MA3 PF02847.17 KHN68902.1 - 0.0059 16.6 0.2 6.5 6.8 0.0 4.2 3 0 0 3 3 3 1 MA3 domain DUF1811 PF08838.10 KHN68902.1 - 0.18 12.1 0.8 0.5 10.6 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) Ribosomal_L15e PF00827.17 KHN68903.1 - 4.3e-80 268.0 7.6 4.9e-80 267.8 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Fip1 PF05182.13 KHN68904.1 - 8.8e-23 79.6 3.8 1.5e-22 78.8 3.8 1.4 1 0 0 1 1 1 1 Fip1 motif RNA_POL_M_15KD PF02150.16 KHN68905.1 - 4.2e-10 39.3 3.3 4.2e-10 39.3 3.3 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KHN68905.1 - 5e-06 26.3 9.7 8.3e-06 25.6 0.9 3.1 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) PaaX_C PF08223.11 KHN68905.1 - 0.044 14.1 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain zinc_ribbon_10 PF10058.9 KHN68905.1 - 0.96 9.2 14.0 0.54 10.0 2.1 3.0 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_4 PF13717.6 KHN68905.1 - 9 6.3 16.3 14 5.7 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain TPP1 PF10341.9 KHN68906.1 - 6.6e-10 39.0 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD AAA_2 PF07724.14 KHN68907.1 - 3.4e-42 144.5 0.9 3.2e-39 134.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KHN68907.1 - 6.3e-28 96.8 1.1 6.3e-28 96.8 1.1 2.6 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 KHN68907.1 - 8.9e-26 90.9 0.2 4.1e-13 49.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KHN68907.1 - 3.6e-18 65.9 0.5 1.2e-10 41.6 0.1 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 KHN68907.1 - 3.3e-15 55.9 0.4 5.1e-14 52.1 0.2 3.2 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 KHN68907.1 - 4.5e-14 53.2 0.1 6e-05 23.5 0.0 4.8 3 1 1 4 4 4 2 AAA ATPase domain IstB_IS21 PF01695.17 KHN68907.1 - 3.9e-09 36.5 0.1 0.00049 19.9 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 KHN68907.1 - 4.6e-09 36.2 0.3 3e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 KHN68907.1 - 2.2e-07 30.5 0.7 0.079 12.3 0.2 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KHN68907.1 - 3.9e-07 30.4 1.7 0.059 13.7 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KHN68907.1 - 1e-06 28.4 0.0 0.054 13.0 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_14 PF13173.6 KHN68907.1 - 1.7e-06 28.1 0.0 0.0086 16.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain Clp_N PF02861.20 KHN68907.1 - 1.8e-06 28.0 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component TsaE PF02367.17 KHN68907.1 - 3.7e-06 26.9 0.1 0.041 13.9 0.0 3.0 2 1 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KHN68907.1 - 4.4e-06 26.5 2.2 0.056 13.2 0.0 4.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 KHN68907.1 - 5.8e-06 25.8 0.0 0.47 9.8 0.0 3.5 2 1 1 3 3 3 2 Bacterial TniB protein NACHT PF05729.12 KHN68907.1 - 6.5e-06 26.2 0.0 0.03 14.2 0.0 2.8 2 0 0 2 2 2 2 NACHT domain TIP49 PF06068.13 KHN68907.1 - 6.5e-06 25.6 3.5 0.15 11.2 0.2 3.4 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_18 PF13238.6 KHN68907.1 - 1.1e-05 26.0 2.4 0.062 13.8 0.1 4.2 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KHN68907.1 - 1.8e-05 24.1 0.1 0.053 12.8 0.0 3.0 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KHN68907.1 - 2.2e-05 24.4 0.2 0.061 13.2 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase CbiA PF01656.23 KHN68907.1 - 2.6e-05 24.3 0.0 0.33 11.0 0.0 3.3 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 KHN68907.1 - 3.8e-05 23.9 0.0 0.54 10.5 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KHN68907.1 - 6.2e-05 22.8 0.3 0.023 14.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KHN68907.1 - 9.6e-05 22.7 0.0 0.51 10.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 KHN68907.1 - 0.00011 22.0 0.1 0.048 13.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KHN68907.1 - 0.00012 22.2 1.1 0.17 11.9 0.0 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KHN68907.1 - 0.00012 22.7 1.6 0.33 11.5 0.0 3.7 3 1 0 3 3 3 1 ABC transporter NTPase_1 PF03266.15 KHN68907.1 - 0.00018 21.5 0.8 0.3 11.0 0.2 3.4 2 1 1 3 3 3 1 NTPase ATPase_2 PF01637.18 KHN68907.1 - 0.00018 21.5 6.4 0.055 13.4 0.1 4.0 3 1 0 4 4 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KHN68907.1 - 0.00058 19.5 2.4 0.22 11.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KHN68907.1 - 0.00062 19.0 0.2 0.17 11.1 0.1 2.8 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 KHN68907.1 - 0.00064 19.0 0.1 0.31 10.2 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 KHN68907.1 - 0.0008 19.8 0.5 0.47 10.8 0.6 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KHN68907.1 - 0.0013 19.2 11.5 0.95 9.9 0.1 3.7 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.17 KHN68907.1 - 0.0021 18.2 0.0 0.0021 18.2 0.0 3.6 3 1 1 4 4 2 1 Helicase HerA, central domain AAA_29 PF13555.6 KHN68907.1 - 0.0021 17.7 0.1 3.3 7.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Torsin PF06309.11 KHN68907.1 - 0.0024 18.0 0.0 0.013 15.6 0.0 2.2 3 0 0 3 3 1 1 Torsin ParA PF10609.9 KHN68907.1 - 0.0032 16.9 1.1 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase DNA_pol3_delta2 PF13177.6 KHN68907.1 - 0.0033 17.2 0.0 0.24 11.2 0.0 3.3 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_17 PF13207.6 KHN68907.1 - 0.0038 17.7 1.2 24 5.3 0.0 4.5 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 KHN68907.1 - 0.0054 15.8 0.0 0.36 9.9 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 KHN68907.1 - 0.0063 16.7 0.1 5.2 7.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 KHN68907.1 - 0.011 15.2 0.3 1 8.8 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein Bac_DnaA PF00308.18 KHN68907.1 - 0.016 15.1 0.0 0.58 10.0 0.0 2.9 3 0 0 3 3 2 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 KHN68907.1 - 0.017 15.2 0.1 2.1 8.4 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase SRP54 PF00448.22 KHN68907.1 - 0.025 14.2 0.4 4.2 6.9 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_31 PF13614.6 KHN68907.1 - 0.025 14.5 1.7 0.73 9.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain ArsA_ATPase PF02374.15 KHN68907.1 - 0.037 13.2 4.8 2.1 7.4 0.0 3.6 3 1 0 3 3 3 0 Anion-transporting ATPase DnaB_C PF03796.15 KHN68907.1 - 0.044 13.1 0.1 1.4 8.2 0.1 2.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_8 PF12780.7 KHN68907.1 - 0.062 12.6 0.0 3.2 7.0 0.0 2.8 3 0 0 3 3 2 0 P-loop containing dynein motor region D4 FtsK_SpoIIIE PF01580.18 KHN68907.1 - 0.065 12.6 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_3 PF07726.11 KHN68907.1 - 0.065 13.1 0.1 8 6.3 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Noelin-1 PF12308.8 KHN68907.1 - 1.4 8.9 4.2 3 7.9 2.3 2.6 3 0 0 3 3 1 0 Neurogenesis glycoprotein DUF347 PF03988.12 KHN68908.1 - 0.09 13.0 1.1 0.09 13.0 1.1 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Shisa PF13908.6 KHN68908.1 - 5.9 7.1 6.0 1.4e+02 2.6 6.0 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator S_4TM PF18159.1 KHN68908.1 - 7.3 5.8 6.8 13 5.0 6.8 1.5 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain TP_methylase PF00590.20 KHN68909.1 - 1e-14 55.0 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases WD40 PF00400.32 KHN68911.1 - 2.2e-10 40.9 6.2 0.058 14.3 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN68911.1 - 0.0014 18.9 0.0 9.4 6.6 0.0 4.0 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KHN68911.1 - 0.032 14.3 0.1 7.2 6.7 0.0 2.8 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KHN68911.1 - 0.058 12.1 0.0 0.28 9.9 0.0 1.9 2 1 1 3 3 3 0 Nup133 N terminal like GTP_EFTU PF00009.27 KHN68912.1 - 1.3e-57 194.5 0.0 2e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KHN68912.1 - 6.4e-19 67.9 0.1 2e-18 66.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KHN68912.1 - 8.7e-19 67.4 0.0 2.1e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KHN68912.1 - 1.7e-10 41.1 0.0 3.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KHN68912.1 - 5.4e-10 39.2 0.0 1.8e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KHN68912.1 - 0.0022 18.1 0.1 0.0058 16.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase CBFD_NFYB_HMF PF00808.23 KHN68913.1 - 3e-08 33.8 0.4 5e-08 33.1 0.4 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KHN68913.1 - 0.00038 20.8 0.3 0.00046 20.5 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_M26_N PF05342.14 KHN68913.1 - 0.032 13.6 0.1 0.039 13.4 0.1 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region IFN-gamma PF00714.17 KHN68914.1 - 0.023 14.6 0.6 0.034 14.0 0.6 1.4 1 0 0 1 1 1 0 Interferon gamma DUF382 PF04037.13 KHN68915.1 - 1.3e-26 93.2 0.0 1.3e-26 93.2 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KHN68915.1 - 7.8e-17 60.9 1.3 1.5e-16 60.0 1.3 1.5 1 0 0 1 1 1 1 PSP Pkinase PF00069.25 KHN68916.1 - 5.8e-49 166.8 0.1 7e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN68916.1 - 4.7e-30 104.7 0.0 5.6e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KHN68916.1 - 0.02 13.7 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KHN68916.1 - 0.043 13.1 0.0 0.078 12.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 KHN68916.1 - 0.098 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cation_efflux PF01545.21 KHN68917.1 - 2.4e-46 158.0 12.6 3.3e-46 157.5 12.6 1.1 1 0 0 1 1 1 1 Cation efflux family GtrA PF04138.14 KHN68917.1 - 9.9 6.4 9.4 27 5.0 5.8 3.0 1 1 1 2 2 2 0 GtrA-like protein Methyltransf_4 PF02390.17 KHN68918.1 - 5.9e-43 146.3 0.0 7.3e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KHN68918.1 - 6.2e-05 23.6 0.0 0.00016 22.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KHN68918.1 - 7.5e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 KHN68918.1 - 0.00082 19.0 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KHN68918.1 - 0.00095 19.8 0.0 0.023 15.3 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.6 KHN68918.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KHN68918.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 KHN68918.1 - 0.014 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KHN68918.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KHN68918.1 - 0.039 14.7 0.1 0.12 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_20 PF12147.8 KHN68918.1 - 0.099 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NblA PF04485.12 KHN68919.1 - 0.076 13.4 0.9 0.2 12.1 0.9 1.7 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA AP_endonuc_2 PF01261.24 KHN68920.1 - 1e-33 116.6 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Syntaxin PF00804.25 KHN68921.1 - 1.5e-12 47.6 15.1 1.9e-12 47.3 15.1 1.2 1 0 0 1 1 1 1 Syntaxin DUF4407 PF14362.6 KHN68921.1 - 0.00019 20.9 9.2 0.0013 18.1 2.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) SNARE PF05739.19 KHN68921.1 - 0.00052 20.0 1.4 0.002 18.1 1.4 2.1 1 0 0 1 1 1 1 SNARE domain DUF1319 PF07028.11 KHN68921.1 - 0.00079 19.6 0.0 0.02 15.1 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1319) DUF2721 PF11026.8 KHN68921.1 - 0.019 14.9 6.7 0.15 12.0 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) AAA_13 PF13166.6 KHN68921.1 - 0.027 13.1 17.9 0.055 12.1 17.9 1.5 1 1 0 1 1 1 0 AAA domain DUF4446 PF14584.6 KHN68921.1 - 0.04 13.9 0.3 0.04 13.9 0.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) FAD_SOX PF18371.1 KHN68921.1 - 0.067 13.6 0.9 1.7 9.0 0.0 2.8 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF1213 PF06740.12 KHN68921.1 - 0.086 13.4 0.0 0.3 11.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) Laminin_II PF06009.12 KHN68921.1 - 0.1 12.6 9.1 1.9 8.5 2.6 2.4 2 0 0 2 2 2 0 Laminin Domain II Cupin_8 PF13621.6 KHN68921.1 - 0.13 11.9 5.2 0.41 10.3 5.2 1.8 1 1 0 1 1 1 0 Cupin-like domain Spectrin PF00435.21 KHN68921.1 - 0.17 12.3 6.6 3.8 8.1 0.9 2.7 3 0 0 3 3 3 0 Spectrin repeat Folliculin PF11704.8 KHN68921.1 - 0.23 11.3 5.2 0.12 12.2 1.6 2.0 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Syntaxin-18_N PF10496.9 KHN68921.1 - 0.51 10.6 6.7 0.31 11.3 0.3 3.1 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Uso1_p115_C PF04871.13 KHN68921.1 - 3.3 8.1 13.1 1.9 8.9 1.4 3.0 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2116 PF09889.9 KHN68921.1 - 6.4 6.8 5.0 3.2 7.8 2.3 1.9 2 0 0 2 2 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FlxA PF14282.6 KHN68921.1 - 8.7 6.4 8.7 9.9 6.2 4.3 2.7 2 1 0 2 2 2 0 FlxA-like protein zf-CHY PF05495.12 KHN68922.1 - 3.6e-13 49.8 31.0 1.1e-11 45.0 14.0 3.4 3 0 0 3 3 3 3 CHY zinc finger ABC_tran PF00005.27 KHN68923.1 - 3.1e-35 121.7 0.2 2.4e-16 60.5 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KHN68923.1 - 7.9e-11 41.8 8.2 0.00036 20.0 0.6 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 KHN68923.1 - 1.1e-10 41.2 0.9 1.1e-10 41.2 0.9 2.1 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KHN68923.1 - 6.2e-08 32.8 9.5 0.11 12.3 3.9 4.3 2 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KHN68923.1 - 2e-05 24.6 0.3 0.038 13.9 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 KHN68923.1 - 2.5e-05 23.9 0.4 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.27 KHN68923.1 - 9.2e-05 22.1 2.4 9.2e-05 22.1 2.4 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 KHN68923.1 - 0.00013 21.9 10.0 0.018 15.1 1.6 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain AAA_16 PF13191.6 KHN68923.1 - 0.00023 21.6 0.0 0.056 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 KHN68923.1 - 0.00025 20.9 16.0 0.037 13.7 0.8 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 KHN68923.1 - 0.0045 17.4 0.1 1.8 9.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KHN68923.1 - 0.0052 16.7 1.2 0.26 11.2 0.0 3.2 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 KHN68923.1 - 0.0065 16.9 0.1 6.3 7.2 0.0 3.0 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 KHN68923.1 - 0.008 16.1 0.4 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Fer4_7 PF12838.7 KHN68923.1 - 0.0083 16.7 1.9 0.0083 16.7 1.9 2.5 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KHN68923.1 - 0.0083 16.2 2.1 0.0083 16.2 2.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 KHN68923.1 - 0.011 16.6 7.1 0.035 15.1 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 KHN68923.1 - 0.013 15.6 15.1 0.028 14.6 15.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 KHN68923.1 - 0.027 14.6 13.0 0.052 13.7 13.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain DnaB_C PF03796.15 KHN68923.1 - 0.078 12.3 0.8 2.3 7.5 0.0 2.9 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain DUF359 PF04019.12 KHN68923.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF359) SRP54 PF00448.22 KHN68923.1 - 0.15 11.6 0.3 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 KHN68923.1 - 0.17 12.2 0.0 19 5.6 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KHN68923.1 - 0.84 9.7 3.5 26 4.9 0.1 3.1 2 2 0 2 2 2 0 50S ribosome-binding GTPase Fer4_2 PF12797.7 KHN68923.1 - 0.84 9.9 10.9 0.11 12.7 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 KHN68923.1 - 2.6 9.2 16.6 0.18 12.8 4.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 KHN68923.1 - 5.9 7.4 12.7 0.18 12.3 1.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Sad1_UNC PF07738.13 KHN68924.1 - 1.5e-21 76.8 0.1 2.7e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Diphthami_syn_2 PF01902.17 KHN68924.1 - 0.054 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase F5_F8_type_C PF00754.25 KHN68924.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain MFS_1 PF07690.16 KHN68925.1 - 0.026 13.5 32.0 0.13 11.1 32.0 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily PseudoU_synth_1 PF01416.20 KHN68926.1 - 4.5e-11 43.2 0.0 8.3e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Ribosomal_S19e PF01090.19 KHN68927.1 - 3.1e-34 117.6 0.0 3.4e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e TGT PF01702.18 KHN68928.1 - 0.0017 17.6 2.0 0.0038 16.4 1.7 1.7 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pho88 PF10032.9 KHN68929.1 - 3.3e-37 127.5 5.1 4.2e-37 127.2 5.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) RIC3 PF15361.6 KHN68929.1 - 9.4 6.6 8.0 26 5.2 8.0 1.8 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SUI1 PF01253.22 KHN68930.1 - 2.4e-09 37.6 1.1 4e-09 36.9 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRM_1 PF00076.22 KHN68931.1 - 5.3e-07 29.4 0.0 1.2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KHN68931.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 KHN68931.1 - 1.1 9.1 4.9 1.3 8.9 0.7 2.8 3 0 0 3 3 3 0 CCCH-type zinc finger Proteasome PF00227.26 KHN68932.1 - 3.2e-27 95.2 0.0 3.8e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KHN68932.1 - 0.00058 19.5 0.6 0.0012 18.5 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Myb_DNA-binding PF00249.31 KHN68934.1 - 7.9e-31 106.0 4.4 2.6e-14 53.1 2.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KHN68934.1 - 3.1e-25 88.2 3.8 3.5e-17 62.4 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KHN68934.1 - 0.075 13.1 0.1 6.6 6.8 0.0 2.4 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_7 PF15963.5 KHN68934.1 - 0.093 12.6 0.1 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 Myb DNA-binding like SANT_DAMP1_like PF16282.5 KHN68934.1 - 0.097 12.9 0.1 4.7 7.5 0.0 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 RabGAP-TBC PF00566.18 KHN68935.1 - 4.8e-45 153.9 3.0 6.6e-45 153.4 3.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Tetraspanin PF00335.20 KHN68936.1 - 0.00039 20.2 14.8 0.0022 17.7 14.8 2.0 1 1 0 1 1 1 1 Tetraspanin family NIT PF08376.10 KHN68937.1 - 0.0054 17.2 4.4 1.5 9.2 0.1 2.8 2 1 1 3 3 3 2 Nitrate and nitrite sensing DUF3209 PF11483.8 KHN68937.1 - 0.0059 17.1 0.7 0.0059 17.1 0.7 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3209) Golgin_A5 PF09787.9 KHN68937.1 - 0.37 10.2 45.4 0.0093 15.5 25.9 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KHN68937.1 - 0.6 9.4 37.5 0.29 10.4 23.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) PKcGMP_CC PF16808.5 KHN68937.1 - 1.7 8.5 31.1 0.57 10.1 0.3 6.6 6 0 0 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TolA_bind_tri PF16331.5 KHN68937.1 - 1.9 8.6 17.3 1.5 8.9 0.2 4.4 4 1 0 4 4 4 0 TolA binding protein trimerisation DcrB PF08786.11 KHN68937.1 - 2.9 8.0 8.3 2.9 8.0 0.2 2.9 3 0 0 3 3 3 0 DcrB DUF4337 PF14235.6 KHN68937.1 - 3.3 7.8 0.0 3.3 7.8 0.0 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) IMPa_helical PF18642.1 KHN68937.1 - 8.4 6.9 8.5 3.8 8.0 0.2 3.6 2 1 2 4 4 4 0 Immunomodulating metalloprotease helical domain PUF PF00806.19 KHN68939.1 - 2.1e-44 146.8 11.3 3.8e-07 29.4 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat FA_FANCE PF11510.8 KHN68939.1 - 0.0064 15.9 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE Aa_trans PF01490.18 KHN68940.1 - 5.9e-35 120.8 36.1 8.8e-35 120.2 36.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DsbD_2 PF13386.6 KHN68940.1 - 0.0031 17.5 0.6 0.0031 17.5 0.6 4.0 1 1 0 3 3 3 1 Cytochrome C biogenesis protein transmembrane region UPF0370 PF13980.6 KHN68940.1 - 0.19 11.8 1.6 0.77 9.8 1.6 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) MKT1_C PF12246.8 KHN68940.1 - 0.2 10.9 1.1 3.3 6.9 0.1 2.2 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication WD40 PF00400.32 KHN68941.1 - 1.4e-38 130.1 19.6 2.1e-07 31.5 0.9 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KHN68941.1 - 1.2e-37 129.0 9.4 1.2e-37 129.0 9.4 2.0 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KHN68941.1 - 7.9e-12 45.3 0.1 0.00056 20.2 0.0 5.3 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KHN68941.1 - 0.00026 20.4 0.1 0.47 9.7 0.0 3.6 1 1 2 3 3 3 2 WD40-like domain Nup160 PF11715.8 KHN68941.1 - 0.05 12.2 0.4 0.17 10.5 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KHN68941.1 - 0.14 12.2 0.1 19 5.4 0.0 3.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Arm PF00514.23 KHN68942.1 - 6.4e-37 124.5 7.7 3.8e-10 39.4 0.1 8.3 8 1 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KHN68942.1 - 4.9e-13 49.3 0.0 1.1e-07 32.2 0.0 4.2 3 2 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KHN68942.1 - 1e-09 38.6 0.0 0.017 15.5 0.0 3.8 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 KHN68942.1 - 7.7e-09 35.1 2.6 0.0019 18.3 0.1 5.7 6 0 0 6 6 6 2 HEAT repeat IBB PF01749.20 KHN68942.1 - 2.4e-08 34.3 2.5 5.5e-08 33.1 2.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KHN68942.1 - 2.8e-05 23.6 0.0 5.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Atypical Arm repeat RICTOR_V PF14668.6 KHN68942.1 - 0.00029 21.0 1.6 0.71 10.2 0.0 3.8 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 KHN68942.1 - 0.004 17.2 0.1 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KHN68942.1 - 0.012 14.2 0.5 0.083 11.4 0.2 2.3 2 1 0 2 2 2 0 Adaptin N terminal region Aminotran_5 PF00266.19 KHN68943.1 - 5e-82 275.8 0.0 5.9e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KHN68943.1 - 4.5e-07 29.4 1.2 2.5e-06 27.0 1.2 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KHN68943.1 - 0.011 15.0 0.1 0.015 14.6 0.1 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KHN68943.1 - 0.078 11.7 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain UDPGP PF01704.18 KHN68944.1 - 3.7e-25 88.4 0.1 5.5e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KHN68944.1 - 9.7e-07 29.3 0.0 1.4e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KHN68944.1 - 0.0004 20.1 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 KHN68944.1 - 0.0028 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MSC PF09402.10 KHN68945.1 - 1.5e-15 57.6 7.3 4.4e-10 39.5 3.1 2.7 2 1 1 3 3 3 2 Man1-Src1p-C-terminal domain YABBY PF04690.13 KHN68945.1 - 0.028 15.0 0.1 0.079 13.5 0.1 1.8 1 0 0 1 1 1 0 YABBY protein Tli4_N PF18443.1 KHN68945.1 - 0.075 13.4 0.2 0.2 12.0 0.2 1.7 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Fib_alpha PF08702.10 KHN68945.1 - 0.19 11.9 2.5 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PIRT PF15099.6 KHN68945.1 - 0.29 10.7 3.1 7.3 6.2 0.2 2.8 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family OAD_gamma PF04277.13 KHN68946.1 - 3.7 8.2 4.8 1.3e+02 3.3 0.0 3.4 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Nsp1_C PF05064.13 KHN68947.1 - 0.042 13.7 6.9 0.17 11.7 5.5 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region AROS PF15684.5 KHN68947.1 - 0.047 14.2 1.2 0.076 13.6 1.2 1.3 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 pXO2-34 PF17362.2 KHN68947.1 - 0.1 12.5 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function DUF3818 PF12825.7 KHN68947.1 - 1 8.3 5.1 3.5 6.5 5.0 1.7 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) HSP70 PF00012.20 KHN68948.1 - 6e-14 51.1 9.1 6e-14 51.1 9.1 2.8 3 1 0 3 3 3 1 Hsp70 protein FtsA PF14450.6 KHN68948.1 - 0.0028 18.0 1.7 0.076 13.4 0.8 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Rx_N PF18052.1 KHN68948.1 - 0.015 15.6 1.9 29 5.0 0.1 3.9 2 2 1 4 4 4 0 Rx N-terminal domain Sec20 PF03908.13 KHN68951.1 - 6.4e-08 32.4 1.8 1e-07 31.8 0.9 1.8 1 1 0 1 1 1 1 Sec20 V_ATPase_I PF01496.19 KHN68951.1 - 0.0013 16.7 3.9 0.0016 16.5 3.9 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family VPS28 PF03997.12 KHN68951.1 - 0.0063 16.2 0.9 0.026 14.2 0.3 2.0 2 0 0 2 2 2 1 VPS28 protein TMPIT PF07851.13 KHN68951.1 - 0.014 14.6 6.7 0.02 14.2 6.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein AnfO_nitrog PF09582.10 KHN68951.1 - 0.022 14.1 2.2 0.029 13.7 2.2 1.1 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF547 PF04784.14 KHN68951.1 - 0.034 14.2 0.8 0.18 11.9 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function, DUF547 DUF2116 PF09889.9 KHN68951.1 - 0.06 13.3 3.1 0.089 12.8 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF5345 PF17280.2 KHN68951.1 - 0.15 12.1 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DUF5383 PF17355.2 KHN68951.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5383) WASH-7_C PF14746.6 KHN68951.1 - 0.38 10.4 5.6 2 8.1 2.1 2.3 2 1 0 2 2 2 0 WASH complex subunit 7, C-terminal LMBR1 PF04791.16 KHN68951.1 - 0.62 8.9 4.3 0.79 8.6 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 KHN68951.1 - 2.3 8.4 10.9 1.2 9.3 6.5 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MFS_1_like PF12832.7 KHN68952.1 - 1.5e-15 56.9 27.1 5.9e-15 55.0 27.1 1.9 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KHN68952.1 - 8.8e-09 34.7 24.4 2.6e-07 29.9 24.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KHN68952.1 - 0.00032 19.4 25.8 0.014 13.9 2.8 4.0 3 1 1 4 4 4 4 MFS/sugar transport protein MFS_1_like PF12832.7 KHN68953.1 - 7.5e-28 97.5 26.7 9.3e-26 90.6 26.7 2.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 KHN68953.1 - 4.3e-10 39.0 26.3 1.4e-08 34.0 25.2 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 KHN68953.1 - 4.6e-09 35.7 20.4 9.4e-09 34.7 20.4 1.4 1 1 0 1 1 1 1 Nucleoside H+ symporter NusG_II PF07009.11 KHN68954.1 - 0.077 13.2 0.1 0.15 12.3 0.1 1.4 1 1 0 1 1 1 0 NusG domain II HEAT PF02985.22 KHN68955.1 - 3.3e-06 26.9 0.0 0.15 12.4 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 KHN68955.1 - 0.00035 20.9 0.0 0.48 10.8 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats TFA2_Winged_2 PF18121.1 KHN68955.1 - 0.0031 17.2 0.3 0.033 13.9 0.0 2.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 Turandot PF07240.11 KHN68955.1 - 0.0035 17.3 0.1 0.16 12.0 0.0 3.1 2 0 0 2 2 2 1 Stress-inducible humoral factor Turandot Cnd1 PF12717.7 KHN68955.1 - 0.0095 16.0 7.3 3.3 7.7 0.3 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF1160 PF06648.11 KHN68955.1 - 0.13 12.3 3.4 0.49 10.4 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) Brix PF04427.18 KHN68956.1 - 6.2e-06 26.4 0.1 9.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Brix domain Not1 PF04054.15 KHN68956.1 - 0.026 13.5 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 Tex_N PF09371.10 KHN68956.1 - 0.052 13.2 1.1 6.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain DER1 PF04511.15 KHN68957.1 - 1.9e-38 132.4 11.9 2.3e-38 132.1 11.9 1.1 1 0 0 1 1 1 1 Der1-like family Membralin PF09746.9 KHN68957.1 - 0.053 12.6 6.4 0.099 11.7 6.4 1.6 1 0 0 1 1 1 0 Tumour-associated protein Spt5-NGN PF03439.13 KHN68958.1 - 7.9e-15 54.5 2.0 2.6e-14 52.9 1.1 2.2 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KHN68958.1 - 1.2e-11 44.1 26.8 0.0026 17.7 2.0 6.2 6 0 0 6 6 6 4 KOW motif ProQ_C PF17516.2 KHN68958.1 - 0.067 12.6 1.3 0.52 9.8 0.4 2.6 2 0 0 2 2 2 0 ProQ C-terminal domain DUF150_C PF17384.2 KHN68958.1 - 0.22 11.7 0.9 15 5.8 0.0 4.0 4 1 1 5 5 5 0 RimP C-terminal SH3 domain Brix PF04427.18 KHN68959.1 - 0.00025 21.2 0.2 0.00031 20.9 0.2 1.3 1 1 0 1 1 1 1 Brix domain Septin PF00735.18 KHN68960.1 - 2.8e-59 200.7 1.5 1e-58 198.9 1.5 1.8 1 1 0 1 1 1 1 Septin Sipho_tail PF05709.11 KHN68960.1 - 0.0066 15.9 3.1 1.4 8.2 0.2 2.6 3 0 0 3 3 3 2 Phage tail protein MMR_HSR1 PF01926.23 KHN68960.1 - 0.09 12.9 0.1 0.21 11.7 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KHN68960.1 - 0.21 11.1 0.8 1.3 8.5 0.3 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 KHN68962.1 - 6.2e-20 71.2 9.3 5.4e-05 23.9 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KHN68962.1 - 0.0013 17.4 0.0 0.0022 16.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.8 KHN68962.1 - 0.002 16.8 0.4 0.064 11.9 0.1 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KHN68962.1 - 0.024 14.9 0.0 4.5 7.7 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KHN68962.1 - 0.24 11.9 0.3 38 4.9 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain UQ_con PF00179.26 KHN68963.1 - 1.4e-43 147.9 0.0 1.6e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KHN68963.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KHN68963.1 - 0.0018 18.6 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain SMC_N PF02463.19 KHN68964.1 - 3.5e-17 62.6 30.2 1.8e-16 60.3 30.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KHN68964.1 - 8.8e-14 52.0 1.3 8.8e-14 52.0 1.3 3.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KHN68964.1 - 4e-07 30.2 2.6 0.0004 20.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KHN68964.1 - 9.4e-06 26.3 32.1 9.4e-06 26.3 32.1 6.0 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KHN68964.1 - 3.1e-05 23.6 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 KHN68964.1 - 9.5e-05 22.1 0.0 9.5e-05 22.1 0.0 4.5 5 1 0 5 5 5 1 AAA domain DUF1515 PF07439.11 KHN68964.1 - 0.15 12.1 0.1 0.15 12.1 0.1 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1515) Ins134_P3_kin_N PF17927.1 KHN68964.1 - 0.29 11.6 1.7 0.71 10.3 0.5 2.3 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain NPV_P10 PF05531.12 KHN68964.1 - 3.1 8.3 13.1 0.2 12.1 1.2 4.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Fas_alpha_ACP PF18325.1 KHN68965.1 - 0.032 14.6 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain Sarcoglycan_2 PF05510.13 KHN68965.1 - 0.05 12.4 0.1 0.065 12.0 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Peptidase_C98 PF15499.6 KHN68965.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Kinesin PF00225.23 KHN68966.1 - 2.8e-81 273.1 1.9 6.2e-81 271.9 1.9 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KHN68966.1 - 1.7e-19 70.2 0.1 5.7e-19 68.5 0.1 1.9 1 1 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 KHN68966.1 - 0.011 16.0 0.0 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif STE PF02200.16 KHN68967.1 - 4.4e-53 178.4 0.3 7.4e-53 177.6 0.3 1.4 1 0 0 1 1 1 1 STE like transcription factor CheZ PF04344.13 KHN68968.1 - 0.0034 17.3 0.7 0.0047 16.9 0.7 1.4 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ tRNA_synt_1c_R1 PF04558.15 KHN68968.1 - 0.044 13.8 0.6 0.065 13.2 0.6 1.5 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Glyco_hydro_114 PF03537.13 KHN68968.1 - 0.083 12.2 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 RNase_PH PF01138.21 KHN68969.1 - 0.00032 21.2 0.0 0.0011 19.5 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KHN68969.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF3427 PF11907.8 KHN68969.1 - 0.09 12.0 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3427) DUF1256 PF06866.11 KHN68970.1 - 0.034 13.6 0.2 0.34 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1256) DUF3237 PF11578.8 KHN68970.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Stb3 PF10330.9 KHN68970.1 - 0.09 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative Sin3 binding protein Ribosomal_L29 PF00831.23 KHN68971.1 - 7.8e-09 35.4 5.8 7.8e-09 35.4 5.8 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF4140 PF13600.6 KHN68971.1 - 0.011 16.2 3.2 0.019 15.4 0.5 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4111 PF13427.6 KHN68971.1 - 0.027 14.6 0.6 0.041 14.0 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4111) HD_assoc PF13286.6 KHN68971.1 - 0.044 14.3 0.4 0.11 13.1 0.3 1.8 1 1 0 1 1 1 0 Phosphohydrolase-associated domain FliH PF02108.16 KHN68971.1 - 0.076 13.1 2.8 0.093 12.8 2.8 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH LSM PF01423.22 KHN68972.1 - 4.9e-08 32.5 0.4 8.5e-08 31.8 0.4 1.4 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KHN68972.1 - 9e-05 22.5 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain eIF-5a PF01287.20 KHN68972.1 - 0.058 13.5 0.1 0.079 13.1 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF2089 PF09862.9 KHN68973.1 - 0.099 12.7 0.2 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Nuf2 PF03800.14 KHN68974.1 - 1.5e-27 96.4 0.2 8e-27 94.0 0.0 2.3 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KHN68974.1 - 0.00028 20.9 1.8 0.00028 20.9 1.8 3.8 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain APG6_N PF17675.1 KHN68974.1 - 0.0052 17.3 11.6 0.0052 17.3 11.6 3.0 2 1 0 2 2 2 1 Apg6 coiled-coil region Lebercilin PF15619.6 KHN68974.1 - 0.0063 16.2 9.5 0.0063 16.2 9.5 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease DUF4472 PF14739.6 KHN68974.1 - 0.0096 16.6 3.7 0.0096 16.6 3.7 3.3 2 2 0 2 2 2 1 Domain of unknown function (DUF4472) Fez1 PF06818.15 KHN68974.1 - 0.019 15.4 23.1 0.15 12.5 9.4 2.4 2 0 0 2 2 2 0 Fez1 CENP-F_leu_zip PF10473.9 KHN68974.1 - 0.022 14.8 31.8 0.51 10.3 14.8 3.8 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Spc19 PF08287.11 KHN68974.1 - 0.051 13.5 20.4 0.11 12.4 8.0 2.8 2 1 0 2 2 2 0 Spc19 FlaC_arch PF05377.11 KHN68974.1 - 0.08 13.3 0.6 0.08 13.3 0.6 5.9 6 1 1 7 7 5 0 Flagella accessory protein C (FlaC) Tmpp129 PF10272.9 KHN68974.1 - 0.12 11.6 4.9 2.2 7.5 0.5 2.3 2 0 0 2 2 2 0 Putative transmembrane protein precursor ERM PF00769.19 KHN68974.1 - 0.16 11.8 27.0 0.52 10.1 6.6 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 KHN68974.1 - 0.26 11.1 27.8 0.32 10.8 2.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF5082 PF16888.5 KHN68974.1 - 0.37 11.1 26.6 0.21 11.8 9.5 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 KHN68974.1 - 0.4 10.2 19.4 1.1 8.8 3.5 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.11 KHN68974.1 - 0.42 10.9 10.8 0.79 10.0 0.4 4.7 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 KHN68974.1 - 0.49 9.4 29.1 0.5 9.4 10.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 KHN68974.1 - 0.75 9.8 27.4 0.25 11.4 1.4 4.4 2 1 2 5 5 4 0 Protein of unknown function (DUF1664) MetOD2 PF18548.1 KHN68974.1 - 0.81 9.8 16.7 3.9 7.6 2.6 4.9 3 2 1 4 4 4 0 Metanogen output domain 2 YgbB PF02542.16 KHN68974.1 - 0.89 9.8 5.0 0.41 10.9 0.8 2.5 1 1 2 3 3 2 0 YgbB family CALCOCO1 PF07888.11 KHN68974.1 - 1.3 7.8 25.4 0.39 9.5 6.9 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 KHN68974.1 - 2.1 7.1 33.0 0.58 9.0 9.2 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein Noelin-1 PF12308.8 KHN68974.1 - 2.2 8.3 20.6 0.84 9.6 0.6 4.2 2 2 2 4 4 4 0 Neurogenesis glycoprotein CCDC74_C PF14917.6 KHN68974.1 - 2.2 8.8 9.0 2.3 8.8 3.6 2.4 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal NPV_P10 PF05531.12 KHN68974.1 - 2.3 8.7 10.0 3.4 8.2 0.4 4.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 KHN68974.1 - 3 8.4 16.5 0.11 13.0 1.7 3.2 2 1 1 3 3 3 0 Spectrin repeat CorA PF01544.18 KHN68974.1 - 3.1 7.0 18.9 2 7.6 4.0 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ATG16 PF08614.11 KHN68974.1 - 3.5 7.8 22.3 8.2 6.6 9.9 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 KHN68974.1 - 4.5 6.7 32.2 3 7.2 7.6 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 UPF0242 PF06785.11 KHN68974.1 - 4.6 7.3 28.2 6.7 6.8 9.6 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 KHN68974.1 - 5.4 6.2 23.4 0.51 9.6 1.2 3.6 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) Tweety PF04906.13 KHN68974.1 - 6.2 5.4 8.9 0.36 9.4 1.2 2.1 2 0 0 2 2 2 0 Tweety Jnk-SapK_ap_N PF09744.9 KHN68974.1 - 7.1 6.8 26.9 0.87 9.8 4.5 3.0 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF2968 PF11180.8 KHN68974.1 - 7.2 6.2 14.8 1.1 8.8 6.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Baculo_PEP_C PF04513.12 KHN68974.1 - 7.5 6.6 11.2 2.6 8.1 3.1 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 KHN68974.1 - 7.5 6.6 22.9 2.9 7.9 7.0 3.2 2 1 1 3 3 3 0 Laminin Domain II TMPIT PF07851.13 KHN68974.1 - 8 5.6 24.0 1.1 8.4 5.9 3.2 2 1 1 3 3 3 0 TMPIT-like protein Fib_alpha PF08702.10 KHN68974.1 - 9 6.5 31.0 0.36 11.0 2.3 3.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family tRNA-synt_2 PF00152.20 KHN68975.1 - 9.3e-81 271.3 0.3 1.3e-80 270.8 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KHN68975.1 - 0.13 11.7 1.7 3.8 6.9 0.0 2.9 4 1 0 4 4 4 0 tRNA synthetases class II core domain (F) DUF2428 PF10350.9 KHN68976.1 - 5.6e-06 25.8 1.4 1.6e-05 24.3 1.4 1.7 1 1 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) CAMSAP_CH PF11971.8 KHN68976.1 - 0.069 13.0 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 CAMSAP CH domain DUF2415 PF10313.9 KHN68977.1 - 4.7e-10 39.2 0.2 2.9e-08 33.5 0.0 3.3 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 KHN68977.1 - 9.6e-09 35.4 0.1 0.042 14.1 0.0 4.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KHN68977.1 - 5.8e-06 24.9 0.1 0.05 11.9 0.0 2.6 1 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 KHN68977.1 - 2.2e-05 25.1 6.2 0.68 10.9 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat HPS3_N PF14761.6 KHN68977.1 - 0.00048 19.7 0.2 0.0047 16.5 0.1 2.6 2 1 2 4 4 4 1 Hermansky-Pudlak syndrome 3 NGP1NT PF08153.12 KHN68978.1 - 2.6e-33 114.9 0.2 4.2e-33 114.3 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KHN68978.1 - 9.6e-17 61.1 1.7 5.1e-14 52.3 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KHN68978.1 - 4.3e-06 26.7 0.0 9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KHN68978.1 - 1.3e-05 24.8 0.4 9.1e-05 22.0 0.0 2.3 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.21 KHN68978.1 - 0.0075 15.7 0.2 0.22 11.0 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family Dynamin_N PF00350.23 KHN68978.1 - 0.0097 16.0 0.6 3.8 7.5 0.0 3.3 2 2 2 4 4 4 1 Dynamin family DEAD PF00270.29 KHN68979.1 - 1.6e-36 125.8 0.0 3e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN68979.1 - 3.4e-28 98.2 0.1 9.5e-28 96.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN68979.1 - 0.0063 16.5 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KHN68980.1 - 1 9.3 11.2 2.4 8.1 11.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KHN68980.1 - 3 7.9 17.5 15 5.6 16.9 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KHN68980.1 - 3.7 8.0 14.1 4.9 7.6 12.3 2.3 2 1 0 2 2 2 0 Ring finger domain XPG_I PF00867.18 KHN68981.1 - 2.2e-18 66.4 0.1 1.1e-17 64.2 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KHN68981.1 - 6.9e-12 45.7 0.1 8.6e-11 42.2 0.1 2.5 1 1 0 1 1 1 1 XPG N-terminal domain Tfb5 PF06331.12 KHN68982.1 - 4.1e-17 61.9 0.0 4.4e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sua5_yciO_yrdC PF01300.18 KHN68983.1 - 4.8e-55 185.8 0.0 7.9e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KHN68983.1 - 5.1e-22 78.9 0.0 8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Nop PF01798.18 KHN68984.1 - 3.9e-68 229.4 0.9 6.4e-68 228.7 0.9 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KHN68984.1 - 8e-07 29.3 0.7 4.8e-06 26.9 0.0 2.8 2 0 0 2 2 2 1 NOP5NT (NUC127) domain FIVAR PF07554.13 KHN68984.1 - 0.22 12.3 1.2 0.67 10.8 1.2 1.8 1 0 0 1 1 1 0 FIVAR domain YIF1 PF03878.15 KHN68985.1 - 8.9e-36 123.6 2.8 1.3e-35 123.1 2.8 1.2 1 0 0 1 1 1 1 YIF1 DNA_circ_N PF07157.12 KHN68985.1 - 0.046 14.1 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA circularisation protein N-terminus VID27 PF08553.10 KHN68986.1 - 2.1e-85 286.9 1.6 4.4e-85 285.9 1.6 1.5 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 KHN68986.1 - 6.4e-05 23.2 1.9 0.00035 20.8 2.3 2.1 2 0 0 2 2 2 1 VID27 PH-like domain PQQ_3 PF13570.6 KHN68986.1 - 0.097 13.2 0.0 5.7 7.6 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain FAD_binding_1 PF00667.20 KHN68987.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KHN68987.1 - 7e-12 46.0 0.0 1.4e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KHN68987.1 - 0.0011 19.1 0.2 0.0041 17.3 0.2 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4479 PF14794.6 KHN68987.1 - 0.11 12.4 0.2 6.9 6.6 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) CDC73_C PF05179.14 KHN68989.1 - 3.6e-21 75.5 0.4 6.9e-21 74.6 0.4 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KHN68989.1 - 0.043 13.1 0.2 0.082 12.2 0.0 1.4 2 0 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal PFU PF09070.11 KHN68990.1 - 3.2e-11 43.5 1.0 8e-11 42.2 1.0 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KHN68990.1 - 7.2e-06 26.7 6.2 0.19 12.6 0.2 6.5 9 0 0 9 9 9 1 WD domain, G-beta repeat Kelch_1 PF01344.25 KHN68990.1 - 0.0073 15.9 0.0 0.082 12.5 0.0 2.6 2 0 0 2 2 2 1 Kelch motif WD40_like PF17005.5 KHN68990.1 - 0.013 14.8 2.9 0.18 11.1 0.2 3.2 1 1 1 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 KHN68990.1 - 0.015 15.8 0.1 23 5.6 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain PUL PF08324.11 KHN68990.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 PUL domain DUF3290 PF11694.8 KHN68990.1 - 0.082 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) SET PF00856.28 KHN68991.1 - 3.9e-15 56.6 1.0 3.9e-15 56.6 1.0 2.4 2 2 0 2 2 2 1 SET domain TCR PF03638.15 KHN68991.1 - 2.1 8.8 47.3 1.8 8.9 17.8 3.5 3 0 0 3 3 3 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Med7 PF05983.11 KHN68992.1 - 0.00029 21.0 1.7 0.0023 18.0 1.7 1.9 1 1 0 1 1 1 1 MED7 protein WD40 PF00400.32 KHN68993.1 - 3e-10 40.5 9.1 0.00016 22.4 0.1 4.3 4 1 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 KHN68993.1 - 0.054 12.1 0.0 0.12 11.0 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 V_ATPase_I PF01496.19 KHN68994.1 - 1.2e-177 592.5 40.8 3.4e-136 455.3 30.3 2.8 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family Wbp11 PF09429.10 KHN68994.1 - 9.4 6.7 6.0 23 5.5 0.4 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 AAA_11 PF13086.6 KHN68995.1 - 2.1e-21 76.9 0.3 4.8e-11 42.9 0.0 2.9 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 KHN68995.1 - 2e-20 73.3 10.5 4.2e-12 46.1 0.1 4.0 3 1 1 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 KHN68995.1 - 9e-17 61.6 1.4 1.1e-14 54.7 1.4 2.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Dna2 PF08696.11 KHN68995.1 - 3.7e-14 53.0 6.8 3.7e-14 53.0 6.8 2.8 2 1 0 2 2 2 1 DNA replication factor Dna2 AAA_30 PF13604.6 KHN68995.1 - 1.1e-09 38.4 0.0 1.8e-07 31.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KHN68995.1 - 2e-09 37.9 0.0 9.9e-08 32.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 KHN68995.1 - 1.5e-08 34.3 0.0 3.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.17 KHN68995.1 - 2.9e-05 24.2 0.4 2.9e-05 24.2 0.4 2.9 4 0 0 4 4 3 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 KHN68995.1 - 0.003 17.4 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 Helicase Mg_chelatase PF01078.21 KHN68995.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KHN68995.1 - 0.063 13.7 0.0 0.25 11.8 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KHN68995.1 - 0.074 13.4 0.0 0.46 10.8 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KHN68995.1 - 0.15 12.1 2.3 1 9.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain LSM PF01423.22 KHN68996.1 - 1.1e-12 47.4 0.1 1.5e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Cullin PF00888.22 KHN68997.1 - 0.0015 17.3 3.9 0.0022 16.7 2.6 2.0 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KHN68997.1 - 0.0029 17.6 1.2 0.011 15.8 0.4 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain SEP PF08059.13 KHN68998.1 - 0.0044 17.6 0.0 0.0067 17.0 0.0 1.4 1 0 0 1 1 1 1 SEP domain HOIP-UBA PF16678.5 KHN68998.1 - 0.017 15.1 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 HOIP UBA domain pair UBA PF00627.31 KHN68998.1 - 0.078 12.9 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Cyclin_N PF00134.23 KHN68999.1 - 5.1e-06 26.2 0.0 2.5e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KHN68999.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Transcription factor TFIIB repeat AAA PF00004.29 KHN69000.1 - 1.3e-44 151.9 0.1 9.7e-44 149.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN69000.1 - 1e-12 47.7 0.1 2.1e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KHN69000.1 - 3.2e-08 33.4 2.1 3.4e-08 33.3 0.6 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KHN69000.1 - 5.4e-07 29.7 0.1 2.7e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KHN69000.1 - 6.4e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KHN69000.1 - 1.2e-06 29.0 0.0 2.5e-05 24.8 0.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KHN69000.1 - 1.5e-05 25.3 0.4 0.0064 16.8 0.4 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KHN69000.1 - 5.9e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KHN69000.1 - 0.00044 20.8 0.0 0.0082 16.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 KHN69000.1 - 0.00081 18.7 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KHN69000.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KHN69000.1 - 0.0015 18.3 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 KHN69000.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_3 PF07726.11 KHN69000.1 - 0.0053 16.6 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KHN69000.1 - 0.0057 16.3 0.2 0.11 12.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 KHN69000.1 - 0.0066 15.9 0.1 0.017 14.5 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KHN69000.1 - 0.0068 15.9 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein TsaE PF02367.17 KHN69000.1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KHN69000.1 - 0.01 15.0 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KHN69000.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KHN69000.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KHN69000.1 - 0.014 15.1 0.2 0.074 12.7 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KHN69000.1 - 0.015 15.0 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KHN69000.1 - 0.031 14.7 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 KHN69000.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KHN69000.1 - 0.036 13.4 0.0 0.085 12.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 KHN69000.1 - 0.055 14.0 0.2 0.54 10.8 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 KHN69000.1 - 0.062 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Prot_ATP_OB_N PF17758.1 KHN69000.1 - 0.079 12.6 0.8 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_11 PF13086.6 KHN69000.1 - 0.11 12.3 0.2 0.25 11.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain zf-HC5HC2H_2 PF13832.6 KHN69001.1 - 9e-21 74.1 10.1 9e-21 74.1 10.1 1.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KHN69001.1 - 9.5e-07 29.0 9.9 9.5e-07 29.0 9.9 2.9 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KHN69001.1 - 1.4e-05 24.6 0.5 1.4e-05 24.6 0.5 3.4 3 0 0 3 3 3 1 PHD-finger T3SS_NleG PF06416.12 KHN69001.1 - 0.023 14.6 0.7 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 Effector protein NleG IKI3 PF04762.12 KHN69002.1 - 1.6e-18 66.2 0.7 2.5e-10 39.1 0.0 4.2 4 1 0 5 5 5 4 IKI3 family DUF3219 PF11514.8 KHN69002.1 - 0.011 15.8 0.8 0.046 13.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3219) Prenyltransf PF01255.19 KHN69003.1 - 3.7e-42 144.4 0.5 6.9e-28 97.7 0.1 2.1 1 1 1 2 2 2 2 Putative undecaprenyl diphosphate synthase Forkhead PF00250.18 KHN69003.1 - 0.047 13.9 2.7 0.73 10.1 0.0 2.9 2 1 1 3 3 3 0 Forkhead domain DUF2344 PF10105.9 KHN69004.1 - 0.079 12.8 3.1 0.067 13.0 1.4 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Osmo_CC PF08946.10 KHN69004.1 - 0.48 10.7 7.6 0.16 12.3 1.4 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Folliculin PF11704.8 KHN69004.1 - 1.2 9.0 7.9 0.12 12.3 2.9 1.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport SNF2_N PF00176.23 KHN69005.1 - 9.7e-64 215.3 0.2 9.7e-64 215.3 0.2 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KHN69005.1 - 8.5e-33 113.6 20.2 2.1e-32 112.3 20.2 1.7 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 KHN69005.1 - 3e-23 82.3 0.3 3.5e-21 75.6 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69005.1 - 4.2e-10 39.9 1.4 2.4e-09 37.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN69005.1 - 1.9e-05 24.5 0.3 7.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KHN69005.1 - 0.00016 20.9 11.6 0.00029 20.1 0.0 4.1 4 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 Fibrillarin_2 PF10113.9 KHN69005.1 - 0.71 8.4 4.5 0.5 8.9 0.3 2.1 2 0 0 2 2 2 0 Fibrillarin-like archaeal protein KELK PF15796.5 KHN69006.1 - 0.07 13.6 5.5 0.14 12.6 5.5 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SMC_N PF02463.19 KHN69007.1 - 9.2e-52 175.6 0.0 1.7e-51 174.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KHN69007.1 - 1.2e-19 70.8 0.0 2.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KHN69007.1 - 4.3e-16 60.0 6.4 4.3e-16 60.0 6.4 4.9 2 2 3 5 5 4 1 AAA domain AAA_15 PF13175.6 KHN69007.1 - 1.1e-14 55.0 21.6 2.6e-13 50.5 3.7 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KHN69007.1 - 5.1e-12 46.2 0.0 1.5e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KHN69007.1 - 8.5e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KHN69007.1 - 4.5e-06 27.2 2.3 0.0047 17.4 0.3 3.7 2 2 0 2 2 2 2 ABC transporter DUF2813 PF11398.8 KHN69007.1 - 6.9e-05 22.3 1.2 0.00015 21.2 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2813) AAA_27 PF13514.6 KHN69007.1 - 0.0016 18.1 0.4 0.018 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2802 PF10975.8 KHN69007.1 - 0.015 15.4 0.3 0.096 12.8 0.3 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) AAA_25 PF13481.6 KHN69007.1 - 0.025 14.2 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain GRDB PF07355.12 KHN69007.1 - 0.039 13.2 0.4 0.49 9.6 0.0 2.6 2 0 0 2 2 2 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) SbcCD_C PF13558.6 KHN69007.1 - 0.059 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KHN69007.1 - 0.071 13.0 0.0 8.5 6.3 0.0 2.8 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KHN69007.1 - 0.11 12.4 0.1 0.38 10.6 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase DUF2187 PF09953.9 KHN69008.1 - 0.0038 17.2 0.2 0.0049 16.8 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2187) Ints3 PF10189.9 KHN69009.1 - 0.00014 21.2 4.4 0.0023 17.2 4.4 2.4 1 1 0 1 1 1 1 Integrator complex subunit 3 DUF2316 PF10078.9 KHN69010.1 - 0.09 13.0 0.2 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Zn_ribbon_17 PF17120.5 KHN69010.1 - 0.11 12.1 0.5 0.3 10.8 0.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TB2_DP1_HVA22 PF03134.19 KHN69011.1 - 3.2e-14 52.6 0.6 5.6e-14 51.8 0.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family dCMP_cyt_deam_1 PF00383.23 KHN69012.1 - 9.5e-20 70.4 4.1 9.5e-20 70.4 4.1 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KHN69012.1 - 1.1e-17 64.1 0.5 1.6e-17 63.5 0.5 1.3 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KHN69012.1 - 0.091 12.9 1.2 0.21 11.7 0.8 1.7 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 KHN69012.1 - 0.47 10.5 3.0 0.58 10.2 0.5 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase Myosin_head PF00063.21 KHN69013.1 - 5.8e-126 421.4 19.2 2.9e-108 362.9 12.6 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.19 KHN69013.1 - 3.6e-14 52.9 0.4 1.5e-13 50.9 0.4 2.1 1 0 0 1 1 1 1 DIL domain Sigma54_activat PF00158.26 KHN69013.1 - 0.0066 16.2 0.2 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain Pox_A_type_inc PF04508.12 KHN69013.1 - 0.019 14.8 1.0 0.082 12.8 1.0 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_16 PF13191.6 KHN69013.1 - 0.028 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KHN69013.1 - 0.067 13.7 0.0 11 6.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KHN69013.1 - 0.072 13.4 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Phage_GPO PF05929.11 KHN69013.1 - 0.66 9.5 3.7 7.1 6.2 0.7 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YcxB PF14317.6 KHN69014.1 - 0.024 14.3 0.7 0.046 13.4 0.1 1.9 2 0 0 2 2 2 0 YcxB-like protein DUF5595 PF18077.1 KHN69015.1 - 0.17 12.0 5.5 1.9 8.6 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) DDT PF02791.17 KHN69017.1 - 0.0048 17.2 0.2 0.0048 17.2 0.2 2.2 3 0 0 3 3 3 1 DDT domain APG9 PF04109.16 KHN69018.1 - 2.4e-11 43.3 16.9 1.5e-10 40.7 9.8 2.2 1 1 0 2 2 2 2 Autophagy protein Apg9 NapE PF06796.11 KHN69018.1 - 0.87 9.2 3.5 0.25 10.9 0.3 1.8 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE CAF1A PF12253.8 KHN69019.1 - 5.6e-06 26.4 6.2 1.5e-05 25.1 5.2 2.2 1 1 1 2 2 2 1 Chromatin assembly factor 1 subunit A GIT_CC PF16559.5 KHN69020.1 - 0.02 14.7 4.3 0.02 14.7 4.3 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPD52 PF04201.15 KHN69020.1 - 0.032 13.9 7.6 0.061 12.9 7.6 1.6 1 0 0 1 1 1 0 Tumour protein D52 family zf-C3HC4_2 PF13923.6 KHN69023.1 - 4.9e-07 29.5 5.2 4.9e-07 29.5 5.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KHN69023.1 - 2.3e-06 27.3 5.9 2.3e-06 27.3 5.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KHN69023.1 - 2.7e-06 27.6 4.9 2.7e-06 27.6 4.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KHN69023.1 - 7e-06 25.8 4.9 1.7e-05 24.5 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KHN69023.1 - 7.5e-06 25.8 10.8 1.2e-05 25.1 7.6 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KHN69023.1 - 4.8e-05 23.6 5.1 0.00016 21.9 5.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KHN69023.1 - 0.00097 19.0 4.9 0.00097 19.0 4.9 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KHN69023.1 - 0.0026 17.8 3.2 0.0026 17.8 3.2 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_10 PF16685.5 KHN69023.1 - 0.0062 16.7 7.2 0.0062 16.7 7.2 2.0 1 1 1 2 2 2 1 zinc RING finger of MSL2 zf-RING_13 PF17977.1 KHN69023.1 - 0.028 14.5 4.0 0.18 12.0 1.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 KHN69023.1 - 0.21 11.7 5.4 0.29 11.3 1.3 2.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-RING_4 PF14570.6 KHN69023.1 - 0.23 11.3 6.9 0.097 12.5 3.9 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_recom PF13408.6 KHN69023.1 - 0.35 11.4 11.9 0.9 10.1 9.9 2.5 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.7 KHN69023.1 - 1.1 9.3 7.6 0.78 9.8 4.7 2.3 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 KHN69023.1 - 3.4 7.7 12.8 0.49 10.3 3.8 3.1 2 1 1 3 3 3 0 Nudix N-terminal DUF1272 PF06906.11 KHN69023.1 - 5.1 7.3 11.5 0.19 11.8 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 KHN69023.1 - 6.9 6.9 14.8 0.26 11.5 7.7 2.3 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING RNase_P_Rpp14 PF01900.19 KHN69024.1 - 9.9e-15 54.7 0.1 1.2e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family PK PF00224.21 KHN69025.1 - 5.1e-107 357.7 7.6 7.1e-107 357.3 7.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.14 KHN69025.1 - 0.00053 19.2 0.9 0.0036 16.5 0.4 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PK_C PF02887.16 KHN69025.1 - 0.0019 18.4 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 KHN69025.1 - 0.013 14.6 0.2 0.013 14.6 0.2 2.4 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain BCL_N PF04714.13 KHN69025.1 - 0.068 13.2 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 BCL7, N-terminal conserver region Chromosome_seg PF13889.6 KHN69026.1 - 0.087 13.0 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Chromosome segregation during meiosis Arv1 PF04161.13 KHN69027.1 - 1.5e-21 77.6 13.5 2.1e-21 77.1 13.5 1.2 1 0 0 1 1 1 1 Arv1-like family Zn-ribbon_8 PF09723.10 KHN69027.1 - 0.013 15.6 4.7 0.014 15.5 3.2 1.9 2 0 0 2 2 2 0 Zinc ribbon domain YibE_F PF07907.11 KHN69027.1 - 0.018 14.5 8.4 0.028 13.9 8.4 1.3 1 0 0 1 1 1 0 YibE/F-like protein Hist_deacetyl PF00850.19 KHN69028.1 - 1.3e-63 215.3 0.2 7.5e-63 212.8 0.2 1.9 1 1 0 1 1 1 1 Histone deacetylase domain La PF05383.17 KHN69029.1 - 4.2e-20 71.5 0.7 1.2e-19 70.1 0.1 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 KHN69029.1 - 0.0053 16.5 0.8 0.021 14.6 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.16 KHN69029.1 - 0.028 14.5 0.1 0.062 13.3 0.0 1.8 2 1 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3682 PF12446.8 KHN69029.1 - 0.26 11.8 1.3 0.46 11.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Peptidase_C97 PF05903.14 KHN69030.1 - 1e-31 109.8 0.0 1.1e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KHN69030.1 - 0.12 12.7 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase WW PF00397.26 KHN69031.1 - 2.1e-13 50.1 7.9 6.3e-08 32.6 0.2 3.1 4 0 0 4 4 4 2 WW domain zinc_ribbon_10 PF10058.9 KHN69032.1 - 3.6e-17 61.8 1.1 6.1e-17 61.1 1.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF4355 PF14265.6 KHN69032.1 - 0.00053 20.2 2.6 0.0012 19.1 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4355) CCDC-167 PF15188.6 KHN69032.1 - 0.016 15.5 0.2 0.016 15.5 0.2 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3866 PF12982.7 KHN69032.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DUF2721 PF11026.8 KHN69032.1 - 0.13 12.2 2.3 0.12 12.3 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) PKK PF12474.8 KHN69032.1 - 0.52 10.4 12.8 0.035 14.2 7.0 1.8 2 0 0 2 2 2 0 Polo kinase kinase Proteasome PF00227.26 KHN69033.1 - 3.8e-46 157.0 0.3 4.5e-46 156.8 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 KHN69034.1 - 0.022 14.1 0.0 0.063 12.5 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF2935 PF11155.8 KHN69034.1 - 0.063 13.6 1.6 7.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) MIP-T3 PF10243.9 KHN69034.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain DUF4181 PF13789.6 KHN69034.1 - 0.15 12.4 3.2 5.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) Zip PF02535.22 KHN69035.1 - 4.1e-34 118.3 15.7 5.6e-34 117.8 15.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter NDUF_B12 PF08122.12 KHN69035.1 - 3.4 7.8 4.8 30 4.8 0.0 3.8 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family XRN_N PF03159.18 KHN69037.1 - 5.5e-70 235.5 0.0 8.4e-70 234.9 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 KHN69037.1 - 2.5e-57 194.8 6.1 5.7e-38 131.0 2.2 2.1 1 1 1 2 2 2 2 Xrn1 helical domain zf-CCHC_4 PF14392.6 KHN69037.1 - 0.0044 16.7 0.8 0.015 15.0 0.8 2.0 1 0 0 1 1 1 1 Zinc knuckle C6_DPF PF10170.9 KHN69037.1 - 0.13 12.7 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Cysteine-rich domain DNA_pol_D_N PF18018.1 KHN69038.1 - 1.5e-24 86.6 0.1 2.2e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KHN69038.1 - 1.8e-13 50.4 0.0 3.4e-13 49.4 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B tRNA_anti-codon PF01336.25 KHN69038.1 - 0.036 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RRN3 PF05327.11 KHN69039.1 - 2.7 6.4 13.9 1.1 7.8 0.3 3.4 2 2 0 4 4 4 0 RNA polymerase I specific transcription initiation factor RRN3 PDEase_I PF00233.19 KHN69040.1 - 9.4e-16 58.3 0.0 1.7e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KHN69040.1 - 0.0062 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 HD domain NARG2_C PF10505.9 KHN69040.1 - 0.16 11.4 0.3 0.25 10.8 0.0 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus THUMP PF02926.17 KHN69041.1 - 2.7e-06 27.6 5.7 3.4e-05 24.0 5.7 2.6 1 1 0 1 1 1 1 THUMP domain DUF1465 PF07323.12 KHN69041.1 - 0.074 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DCX PF03607.17 KHN69041.1 - 0.098 12.8 0.1 0.88 9.7 0.0 2.3 2 0 0 2 2 2 0 Doublecortin PhosphMutase PF10143.9 KHN69041.1 - 0.12 12.2 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GTP_EFTU PF00009.27 KHN69042.1 - 1.3e-15 57.5 0.5 2.1e-15 56.8 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KHN69042.1 - 5.3e-07 29.7 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_C PF00679.24 KHN69042.1 - 9.5e-07 28.8 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MeaB PF03308.16 KHN69042.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KHN69042.1 - 0.02 15.4 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ribosomal_S24e PF01282.19 KHN69042.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S24e AAA_16 PF13191.6 KHN69042.1 - 0.072 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 KHN69042.1 - 0.088 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KHN69042.1 - 0.13 12.3 0.0 0.49 10.4 0.0 1.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4925 PF16272.5 KHN69042.1 - 0.17 11.3 3.8 0.42 10.1 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) Septin PF00735.18 KHN69043.1 - 4e-63 213.3 0.0 4.8e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KHN69043.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KHN69043.1 - 7.4e-06 26.1 1.0 0.005 16.9 0.5 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 KHN69043.1 - 0.00012 21.4 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KHN69043.1 - 0.0022 17.1 0.0 0.0093 15.1 0.0 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 KHN69043.1 - 0.0035 16.7 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family FeoB_N PF02421.18 KHN69043.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KHN69043.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KHN69043.1 - 0.032 14.1 0.6 0.36 10.7 0.3 2.5 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 KHN69043.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KHN69043.1 - 0.095 13.2 0.1 0.12 12.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Cyclin_N PF00134.23 KHN69045.1 - 0.0019 17.9 0.1 0.0046 16.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KHN69045.1 - 0.048 13.7 0.1 0.19 11.8 0.1 2.1 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Elf1 PF05129.13 KHN69046.1 - 1.2e-23 82.9 7.2 1.4e-23 82.7 7.2 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 KHN69046.1 - 0.056 12.9 3.7 0.082 12.3 3.7 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 KHN69046.1 - 0.06 13.4 4.5 0.19 11.8 0.7 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger ThiF PF00899.21 KHN69048.1 - 6.9e-29 100.9 1.1 8.6e-29 100.6 1.1 1.1 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.18 KHN69048.1 - 0.0046 17.2 0.4 0.012 15.8 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 KHN69048.1 - 0.059 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KHN69048.1 - 0.089 12.4 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KHN69048.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KHN69048.1 - 0.16 12.2 0.9 1.5 9.1 0.2 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KHN69048.1 - 0.19 12.3 0.5 0.38 11.3 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.24 KHN69048.1 - 0.33 11.4 1.7 12 6.4 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KHN69048.1 - 0.39 10.7 2.1 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 FAD-NAD(P)-binding TPR_1 PF00515.28 KHN69049.1 - 1.7e-13 49.8 2.9 0.0012 18.6 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KHN69049.1 - 4.3e-12 46.1 0.1 3e-07 30.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KHN69049.1 - 1.4e-11 43.6 1.6 0.032 14.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69049.1 - 2.1e-06 27.5 2.6 1.1 9.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KHN69049.1 - 2.9e-06 26.8 1.2 0.3 10.8 0.0 4.7 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 KHN69049.1 - 0.0063 16.8 3.6 3.2 8.3 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KHN69049.1 - 0.0083 16.8 4.4 0.99 10.1 0.2 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KHN69049.1 - 0.009 15.3 0.1 0.32 10.2 0.0 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KHN69049.1 - 0.021 15.6 1.0 31 5.8 0.0 5.2 4 3 2 6 6 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KHN69049.1 - 0.042 13.9 1.6 5.9 7.0 0.2 3.0 3 0 0 3 3 3 0 Putative TPR-like repeat Macoilin PF09726.9 KHN69051.1 - 8.4 4.8 27.3 9.9 4.6 27.3 1.1 1 0 0 1 1 1 0 Macoilin family HEAT PF02985.22 KHN69052.1 - 4.2e-10 39.0 0.1 3.4 8.2 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 KHN69052.1 - 1.3e-07 31.9 0.0 0.039 14.3 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KHN69052.1 - 2.1e-05 24.6 7.1 0.00036 20.6 1.3 3.6 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4476 PF14771.6 KHN69052.1 - 0.023 15.0 0.5 0.098 13.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) Arm_3 PF16186.5 KHN69052.1 - 0.099 12.2 0.0 8 6.1 0.0 2.6 2 0 0 2 2 2 0 Atypical Arm repeat Vac14_Fab1_bd PF12755.7 KHN69052.1 - 0.15 12.7 1.7 52 4.5 0.1 4.0 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DS PF01916.17 KHN69053.1 - 1.6e-112 375.5 0.0 1.9e-112 375.2 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase FtsJ PF01728.19 KHN69054.1 - 3.1e-56 190.3 0.1 3.7e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Yos1 PF08571.10 KHN69055.1 - 5e-21 74.8 0.5 5.8e-21 74.6 0.5 1.0 1 0 0 1 1 1 1 Yos1-like Rad52_Rad22 PF04098.15 KHN69056.1 - 5.1e-53 179.1 0.2 6.3e-53 178.8 0.2 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein BORCS8 PF10167.9 KHN69056.1 - 0.047 13.6 0.3 0.085 12.8 0.3 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 DUF4144 PF13642.6 KHN69056.1 - 0.062 13.9 0.0 0.097 13.3 0.0 1.4 1 0 0 1 1 1 0 protein structure with unknown function FlgT_N PF16548.5 KHN69056.1 - 0.12 13.0 0.5 0.28 11.8 0.3 1.8 2 1 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain Got1 PF04178.12 KHN69057.1 - 2.7e-22 79.3 20.5 3.3e-22 79.0 19.8 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family DUF4181 PF13789.6 KHN69057.1 - 1.6 9.0 12.5 0.25 11.6 7.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) Spore_YabQ PF09578.10 KHN69057.1 - 9.6 6.5 16.5 2.2 8.6 3.1 2.5 1 1 1 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Sec61_beta PF03911.16 KHN69058.1 - 0.00066 19.7 4.2 0.00066 19.7 4.2 2.1 2 0 0 2 2 2 1 Sec61beta family DUF2207 PF09972.9 KHN69058.1 - 0.29 9.8 0.4 0.29 9.9 0.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Bac_surface_Ag PF01103.23 KHN69059.1 - 0.00047 19.7 0.8 0.42 10.1 0.3 3.2 3 1 0 3 3 3 2 Surface antigen SPC22 PF04573.12 KHN69060.1 - 5.2e-12 45.6 0.0 7.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase subunit DEAD PF00270.29 KHN69060.1 - 0.17 11.6 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Metallophos PF00149.28 KHN69061.1 - 8.8e-30 104.7 0.0 1.2e-29 104.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KHN69061.1 - 0.01 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain dCMP_cyt_deam_1 PF00383.23 KHN69062.1 - 0.0013 18.5 0.3 0.0023 17.8 0.3 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KHN69062.1 - 0.0021 17.8 0.1 0.0072 16.1 0.0 1.8 1 1 1 2 2 2 1 MafB19-like deaminase Ribosomal_L3 PF00297.22 KHN69063.1 - 4.3e-124 414.3 11.1 4.9e-124 414.0 11.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2059 PF09832.9 KHN69063.1 - 0.043 13.9 0.1 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) zf-CSL PF05207.13 KHN69064.1 - 9e-22 76.6 0.4 1.2e-21 76.2 0.4 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 KHN69064.1 - 0.057 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 KHN69064.1 - 0.058 13.3 0.2 0.085 12.8 0.2 1.2 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.12 KHN69064.1 - 0.26 9.8 0.1 0.31 9.5 0.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DFRP_C PF16543.5 KHN69065.1 - 3.2e-16 59.6 2.8 3.2e-16 59.6 2.8 2.8 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KHN69065.1 - 1.7e-05 24.6 0.0 1.7e-05 24.6 0.0 2.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KHN69065.1 - 8.1e-05 22.5 0.2 8.1e-05 22.5 0.2 2.2 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KHN69065.1 - 0.0016 19.1 0.7 0.0016 19.1 0.7 2.2 3 0 0 3 3 3 1 Torus domain Fcf2 PF08698.11 KHN69065.1 - 0.0061 16.9 2.0 0.0061 16.9 2.0 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Cwf_Cwc_15 PF04889.12 KHN69065.1 - 0.0063 16.3 13.3 0.19 11.4 0.9 2.2 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein zf-CCCH_2 PF14608.6 KHN69065.1 - 0.0086 16.5 2.6 0.0086 16.5 2.6 2.4 3 0 0 3 3 3 1 RNA-binding, Nab2-type zinc finger Vasculin PF15337.6 KHN69065.1 - 1.2 10.0 8.3 0.37 11.7 0.9 2.6 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 Cyclin_N PF00134.23 KHN69066.1 - 8.1e-24 83.8 1.6 2.1e-23 82.4 0.8 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain E1_dh PF00676.20 KHN69067.1 - 1.5e-70 237.5 0.5 1.9e-70 237.2 0.5 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KHN69067.1 - 0.00041 20.2 0.4 0.00076 19.3 0.4 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 KHN69067.1 - 0.001 18.4 0.0 0.0059 15.8 0.0 2.0 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase RusA PF05866.11 KHN69068.1 - 0.69 10.5 4.3 1.4 9.5 4.3 1.5 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA DUF1240 PF06836.12 KHN69069.1 - 6 7.5 10.0 0.34 11.5 2.6 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1240) SRTM1 PF15872.5 KHN69069.1 - 6.9 6.9 9.5 1.1 9.4 0.7 2.4 1 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Peptidase_C13 PF01650.18 KHN69070.1 - 2e-15 57.0 0.9 2.5e-15 56.7 0.9 1.1 1 0 0 1 1 1 1 Peptidase C13 family SlyX PF04102.12 KHN69071.1 - 0.16 12.6 6.7 11 6.7 0.2 3.4 3 0 0 3 3 3 0 SlyX DUF948 PF06103.11 KHN69071.1 - 5.2 7.4 7.2 17 5.7 1.0 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliD_N PF02465.18 KHN69071.1 - 9.3 7.0 9.0 33 5.3 5.4 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Use1 PF09753.9 KHN69072.1 - 0.00047 20.0 2.3 0.00076 19.3 2.3 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 RIFIN PF02009.16 KHN69072.1 - 0.004 17.1 1.4 0.0046 16.9 1.4 1.1 1 0 0 1 1 1 1 Rifin DUF2207 PF09972.9 KHN69072.1 - 0.0073 15.1 0.5 0.0084 14.9 0.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) RWD PF05773.22 KHN69073.1 - 0.012 15.9 1.5 0.49 10.7 1.5 2.9 1 1 0 1 1 1 0 RWD domain DFRP_C PF16543.5 KHN69073.1 - 0.047 14.2 1.6 0.26 11.8 1.6 2.0 1 1 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 DUF4203 PF13886.6 KHN69074.1 - 2.8 7.6 33.8 76 2.9 33.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Mannosyl_trans2 PF04188.13 KHN69075.1 - 6.5e-34 118.0 32.4 6.3e-18 65.3 9.1 2.3 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 KHN69075.1 - 0.002 18.3 10.9 0.002 18.3 10.9 3.8 3 2 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3855 PF12967.7 KHN69075.1 - 0.061 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) Lectin_leg-like PF03388.13 KHN69076.1 - 2.4e-10 40.1 0.2 3.7e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Legume-like lectin family NCE101 PF11654.8 KHN69076.1 - 1.4 8.7 3.9 0.74 9.6 0.4 2.2 2 0 0 2 2 2 0 Non-classical export protein 1 Phage_GPO PF05929.11 KHN69077.1 - 2.8 7.5 7.4 0.27 10.8 2.7 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Salt_tol_Pase PF09506.10 KHN69078.1 - 0.012 14.4 1.0 0.016 14.0 0.1 1.6 2 0 0 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Ribosomal_S21 PF01165.20 KHN69078.1 - 0.098 12.4 1.1 0.26 11.1 0.9 1.8 1 1 1 2 2 2 0 Ribosomal protein S21 DUF4199 PF13858.6 KHN69078.1 - 0.95 9.8 3.8 16 5.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Spore_II_R PF09551.10 KHN69078.1 - 1.6 9.2 8.5 0.13 12.7 2.5 2.3 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) DUF4446 PF14584.6 KHN69078.1 - 3 7.8 9.8 0.26 11.3 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) NAP PF00956.18 KHN69079.1 - 4.4e-06 26.1 9.2 0.00061 19.0 4.0 2.5 1 1 2 3 3 3 2 Nucleosome assembly protein (NAP) Ribul_P_3_epim PF00834.19 KHN69079.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ABC_tran PF00005.27 KHN69081.1 - 3.7e-23 82.6 0.0 6.4e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KHN69081.1 - 2.1e-09 37.6 0.4 0.0013 18.6 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KHN69081.1 - 0.0015 18.0 0.9 0.054 12.9 1.5 2.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KHN69081.1 - 0.035 14.5 0.0 0.058 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KHN69081.1 - 0.044 13.7 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KHN69081.1 - 0.085 13.1 0.1 0.21 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KHN69081.1 - 0.14 11.8 0.3 5.7 6.5 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 KHN69081.1 - 0.17 11.9 0.0 0.38 10.8 0.0 1.6 1 1 0 1 1 1 0 Dynamin family AAA PF00004.29 KHN69081.1 - 0.17 12.3 0.3 2.9 8.3 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KHN69081.1 - 0.17 10.9 0.2 0.29 10.2 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KHN69081.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 KHN69081.1 - 0.17 11.9 1.0 0.39 10.8 1.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KHN69081.1 - 0.21 12.1 0.1 0.67 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KHN69081.1 - 0.23 11.8 0.2 0.44 10.9 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KHN69081.1 - 0.32 10.7 1.2 0.72 9.6 1.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4229 PF14012.6 KHN69081.1 - 7.1 6.8 10.4 16 5.7 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) zf-B_box PF00643.24 KHN69082.1 - 1.1e-10 41.4 15.1 6.5e-07 29.4 3.4 2.4 2 0 0 2 2 2 2 B-box zinc finger Peptidase_C12 PF01088.21 KHN69082.1 - 0.037 13.8 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 CEBP_ZZ PF16366.5 KHN69082.1 - 0.87 9.9 12.7 3.2 8.1 4.6 2.5 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 KHN69082.1 - 1.7 8.9 10.8 3.2 8.0 1.6 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TrkA_C PF02080.21 KHN69083.1 - 0.023 14.5 0.1 0.059 13.2 0.1 1.7 1 0 0 1 1 1 0 TrkA-C domain DUF3858 PF12970.7 KHN69083.1 - 0.038 14.0 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) LSM PF01423.22 KHN69084.1 - 3.4e-11 42.7 0.4 3.7e-11 42.5 0.4 1.0 1 0 0 1 1 1 1 LSM domain DUF4744 PF15918.5 KHN69084.1 - 0.081 13.8 0.1 0.099 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Tnp_P_element PF12017.8 KHN69085.1 - 0.004 16.6 2.1 0.0062 16.0 2.1 1.3 1 0 0 1 1 1 1 Transposase protein XAF1_C PF18608.1 KHN69085.1 - 0.034 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain PRP21_like_P PF12230.8 KHN69085.1 - 0.036 13.9 0.6 0.077 12.9 0.1 1.7 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-Di19 PF05605.12 KHN69085.1 - 0.08 13.3 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Clat_adaptor_s PF01217.20 KHN69087.1 - 8.8e-16 58.1 4.9 1.7e-15 57.2 4.9 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain EF-hand_7 PF13499.6 KHN69088.1 - 8.7e-14 51.7 5.7 4.2e-08 33.5 0.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KHN69088.1 - 9.8e-09 34.5 1.1 0.018 14.9 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 KHN69088.1 - 8.2e-08 31.3 1.9 0.11 12.1 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 KHN69088.1 - 0.0094 15.4 0.1 0.0094 15.4 0.1 3.0 4 1 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 KHN69088.1 - 0.025 14.9 0.1 7.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KHN69088.1 - 0.05 13.4 4.8 4.1 7.3 0.2 3.2 2 1 1 3 3 3 0 EF-hand domain pair DUF1749 PF08538.10 KHN69090.1 - 1e-19 70.7 0.7 2.5e-19 69.5 0.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KHN69090.1 - 0.0067 17.1 0.0 0.0076 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KHN69090.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase POP1 PF06978.11 KHN69091.1 - 1.2e-18 67.9 16.5 5.4e-11 42.9 5.1 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KHN69091.1 - 7.4e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain ProQ_C PF17516.2 KHN69092.1 - 0.098 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 ProQ C-terminal domain ANAPC4_WD40 PF12894.7 KHN69093.1 - 3.8e-08 33.5 0.2 0.00063 20.0 0.2 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KHN69093.1 - 1.5e-05 25.7 2.9 0.1 13.5 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat BBS2_N PF14781.6 KHN69093.1 - 0.017 15.0 0.0 0.075 12.9 0.0 2.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal UBX PF00789.20 KHN69093.1 - 0.062 13.5 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 UBX domain Ocnus PF05005.15 KHN69093.1 - 0.095 12.8 0.4 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) Pkinase PF00069.25 KHN69094.1 - 3.9e-66 223.1 0.0 4.8e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69094.1 - 2.1e-42 145.2 0.0 2.4e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69094.1 - 2.6e-08 33.5 0.0 2.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KHN69094.1 - 0.0028 17.6 0.2 0.038 13.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KHN69094.1 - 0.0062 15.5 0.0 0.15 11.0 0.0 2.0 1 1 1 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KHN69094.1 - 0.0069 15.8 0.9 0.013 14.8 0.4 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KHN69094.1 - 0.016 14.8 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 RIO1 family MMR_HSR1 PF01926.23 KHN69095.1 - 8.8e-15 54.8 0.1 7.8e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KHN69095.1 - 4.1e-07 29.6 0.0 0.00054 19.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KHN69095.1 - 8.6e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 KHN69095.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family V-ATPase_H_C PF11698.8 KHN69096.1 - 4e-27 94.7 1.1 4e-27 94.7 1.1 2.4 2 1 1 3 3 3 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 KHN69096.1 - 1.9e-09 37.3 2.5 9.1e-09 35.0 2.0 2.2 1 1 0 1 1 1 1 V-ATPase subunit H Cyclin_N PF00134.23 KHN69097.1 - 1.4e-32 112.1 0.6 4.5e-32 110.5 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KHN69097.1 - 3.5e-20 72.3 0.0 7.6e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain MIF4G_like_2 PF09090.11 KHN69098.1 - 1.8e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like Proteasome PF00227.26 KHN69099.1 - 7.3e-30 103.9 0.3 9.1e-30 103.6 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit CODH_A_N PF18537.1 KHN69099.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain MCM PF00493.23 KHN69100.1 - 3.5e-92 307.5 0.4 5.8e-92 306.8 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN69100.1 - 1.2e-28 99.5 0.0 1.3e-26 92.9 0.0 2.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KHN69100.1 - 2e-21 76.2 0.9 4.9e-21 74.9 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KHN69100.1 - 5.9e-08 32.3 0.0 5.8e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KHN69100.1 - 2.5e-06 28.0 0.0 7.3e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 KHN69100.1 - 0.00083 19.2 0.0 0.0031 17.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KHN69100.1 - 0.0087 15.8 0.6 0.07 12.8 0.0 2.7 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_5 PF07728.14 KHN69100.1 - 0.023 14.7 0.0 0.088 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KHN69100.1 - 0.045 14.2 0.7 0.23 11.9 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PIG-L PF02585.17 KHN69101.1 - 3e-17 63.5 0.0 4.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glycophorin_A PF01102.18 KHN69101.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycophorin A WD40_like PF17005.5 KHN69102.1 - 0.003 16.9 0.5 0.01 15.2 0.2 2.1 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 KHN69102.1 - 0.0099 16.2 0.0 6.2 7.2 0.0 3.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KHN69102.1 - 0.056 14.3 0.1 6.9 7.7 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat RNA_pol_Rpb6 PF01192.22 KHN69103.1 - 4.3e-11 42.6 0.0 6.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 ATP_synt_H PF05493.13 KHN69104.1 - 7.7e-12 45.5 2.9 8.6e-12 45.3 2.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H YoqO PF14037.6 KHN69104.1 - 0.0023 18.4 0.5 0.0023 18.4 0.5 1.0 1 0 0 1 1 1 1 YoqO-like protein PGG PF13962.6 KHN69104.1 - 0.031 14.1 0.6 0.034 14.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF4131 PF13567.6 KHN69104.1 - 0.032 13.9 0.5 0.036 13.7 0.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FUSC-like PF12805.7 KHN69104.1 - 0.1 11.6 1.0 0.12 11.5 1.0 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS FeoB_N PF02421.18 KHN69105.1 - 0.00038 20.0 2.2 0.0097 15.4 1.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Adap_comp_sub PF00928.21 KHN69106.1 - 2.4e-06 27.2 4.3 3.9e-06 26.4 4.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family WRNPLPNID PF15017.6 KHN69106.1 - 0.042 14.7 0.4 0.12 13.3 0.4 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF4974 PF16344.5 KHN69106.1 - 0.087 12.8 0.4 1.9 8.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) RNA_pol_Rpb2_1 PF04563.15 KHN69106.1 - 1.1 8.7 6.9 2.2 7.7 6.9 1.4 1 0 0 1 1 1 0 RNA polymerase beta subunit Ribosomal_S19 PF00203.21 KHN69107.1 - 6.9e-22 77.1 0.0 1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Tam41_Mmp37 PF09139.11 KHN69107.1 - 0.028 13.9 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Ribosomal_L10 PF00466.20 KHN69107.1 - 0.13 12.4 0.4 0.32 11.2 0.4 1.8 1 1 0 1 1 1 0 Ribosomal protein L10 Citrate_synt PF00285.21 KHN69107.1 - 0.18 10.8 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Ribosomal_L26 PF16906.5 KHN69109.1 - 2.8e-25 88.6 0.2 4.1e-25 88.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KHN69109.1 - 2.8e-05 23.9 2.9 4.6e-05 23.2 2.9 1.4 1 0 0 1 1 1 1 KOW motif RRM_1 PF00076.22 KHN69110.1 - 2.5e-14 52.8 1.3 3.5e-14 52.4 0.1 1.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 KHN69110.1 - 1.5e-12 47.8 1.4 2.8e-12 46.9 1.4 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 HIT PF01230.23 KHN69111.1 - 3.7e-17 62.8 0.4 5.7e-17 62.3 0.4 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KHN69111.1 - 1.9e-06 28.3 1.4 3.3e-06 27.5 1.4 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KHN69111.1 - 7.8e-05 22.5 0.4 0.00011 22.1 0.3 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Methyltr_RsmB-F PF01189.17 KHN69112.1 - 3.1e-39 134.7 0.0 1e-38 133.0 0.0 1.8 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KHN69112.1 - 0.00019 21.6 0.1 0.0003 21.0 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Homez PF11569.8 KHN69112.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Histone PF00125.24 KHN69113.1 - 7.3e-08 32.8 0.1 1e-07 32.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KHN69113.1 - 0.011 15.9 0.1 0.027 14.7 0.0 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KHN69113.1 - 0.019 15.5 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.6 KHN69113.1 - 0.029 14.8 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein TPR_MLP1_2 PF07926.12 KHN69114.1 - 0.0063 16.6 1.8 0.0063 16.6 1.8 3.8 1 1 3 4 4 4 1 TPR/MLP1/MLP2-like protein DUF2333 PF10095.9 KHN69114.1 - 0.023 13.7 1.6 0.039 13.0 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) ER PF01133.17 KHN69114.1 - 4.6 7.3 7.5 8.2 6.5 0.3 3.0 2 2 0 2 2 2 0 Enhancer of rudimentary GAS PF13851.6 KHN69114.1 - 4.7 6.5 42.3 0.14 11.5 17.2 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KHN69114.1 - 8.2 6.5 26.2 0.2 11.8 2.0 3.7 3 2 0 3 3 3 0 Afadin- and alpha -actinin-Binding CNDH2_N PF06278.11 KHN69115.1 - 0.0089 16.2 0.7 0.0089 16.2 0.7 2.0 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4231 PF14015.6 KHN69115.1 - 0.028 14.9 3.6 0.25 11.8 1.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) ETRAMP PF09716.10 KHN69115.1 - 0.03 14.4 0.6 0.03 14.4 0.6 3.4 3 1 1 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Med26 PF08711.11 KHN69116.1 - 2.8e-12 46.5 0.3 7.8e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Swi3 PF07962.12 KHN69117.1 - 0.0052 16.8 0.0 0.008 16.2 0.0 1.5 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 MSA-2c PF12238.8 KHN69117.1 - 0.12 12.4 0.2 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Toxin_30 PF08117.11 KHN69118.1 - 0.54 10.6 0.2 0.54 10.6 0.2 2.5 3 0 0 3 3 3 0 Ptu family Pro_isomerase PF00160.21 KHN69119.1 - 7.1e-43 146.6 0.1 8.5e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bacteriocin_IIi PF11758.8 KHN69119.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin tRNA-synt_1e PF01406.19 KHN69121.1 - 9.4e-115 383.1 4.0 1.7e-114 382.3 4.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KHN69121.1 - 6.5e-14 51.5 3.7 3.2e-08 32.7 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KHN69121.1 - 1.2e-05 23.8 0.1 0.00047 18.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 KHN69121.1 - 0.029 13.3 0.3 0.029 13.3 0.3 3.0 4 1 1 5 5 5 0 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_S7e PF01251.18 KHN69121.1 - 0.045 13.5 0.4 0.084 12.6 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e DUF1447 PF07288.11 KHN69121.1 - 0.44 10.6 4.5 4.1 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1447) fn3_5 PF06280.12 KHN69123.1 - 0.042 14.5 0.1 0.5 11.1 0.0 2.2 2 0 0 2 2 2 0 Fn3-like domain DDHD PF02862.17 KHN69123.1 - 0.11 12.7 2.4 0.14 12.3 2.4 1.2 1 0 0 1 1 1 0 DDHD domain RRM_1 PF00076.22 KHN69124.1 - 3.7e-37 126.0 1.1 2.7e-13 49.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KHN69124.1 - 0.00093 19.3 1.8 1.8 8.7 0.4 4.1 3 1 0 3 3 3 1 RNA recognition motif RRM_Rrp7 PF17799.1 KHN69124.1 - 0.00094 19.0 0.2 1.7 8.4 0.0 3.7 3 1 1 4 4 4 2 Rrp7 RRM-like N-terminal domain NAS PF03059.16 KHN69124.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein PHM7_cyt PF14703.6 KHN69124.1 - 0.43 10.8 2.2 7.7 6.7 0.1 3.3 3 2 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter BioY PF02632.14 KHN69125.1 - 0.0052 16.8 4.0 0.0052 16.8 4.0 2.6 3 1 0 3 3 3 1 BioY family Phage_holin_2_3 PF16080.5 KHN69125.1 - 0.37 10.6 0.1 0.37 10.6 0.1 3.0 3 1 0 3 3 3 0 Bacteriophage holin family HP1 SirB PF04247.12 KHN69125.1 - 0.99 9.5 21.9 0.21 11.7 5.4 3.0 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB Abhydrolase_9_N PF15420.6 KHN69125.1 - 2 8.4 9.8 2 8.3 0.2 2.9 1 1 2 3 3 3 0 Alpha/beta-hydrolase family N-terminus LSM PF01423.22 KHN69126.1 - 2.7e-16 59.0 0.3 3.1e-16 58.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KHN69126.1 - 0.008 16.3 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KHN69126.1 - 0.036 14.2 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 KHN69126.1 - 0.051 13.7 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain tRNA-synt_1d PF00750.19 KHN69127.1 - 1.2e-78 264.5 2.2 1.8e-78 264.0 2.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KHN69127.1 - 2.7e-23 82.4 0.0 8.8e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Myotub-related PF06602.14 KHN69127.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain zf-C2H2 PF00096.26 KHN69128.1 - 1.6e-07 31.4 18.4 0.00057 20.2 3.6 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KHN69128.1 - 2.8e-05 24.3 3.7 2.8e-05 24.3 3.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KHN69128.1 - 0.00043 20.9 15.2 0.049 14.5 2.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KHN69128.1 - 0.0023 18.5 1.3 0.33 11.6 0.1 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain RPAP2_Rtr1 PF04181.13 KHN69128.1 - 3.7 7.9 8.4 0.72 10.2 0.2 3.0 3 0 0 3 3 3 0 Rtr1/RPAP2 family DUF572 PF04502.13 KHN69129.1 - 3.6e-28 99.1 0.2 4.4e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 KHN69129.1 - 0.035 14.0 0.4 0.047 13.6 0.4 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.12 KHN69129.1 - 0.19 11.3 1.2 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ACC PF17848.1 KHN69129.1 - 9.6 6.4 7.1 5.6 7.1 0.6 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain T2SSB PF16537.5 KHN69131.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 0 Type II secretion system protein B Laminin_G_3 PF13385.6 KHN69131.1 - 0.013 15.6 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily DUF2118 PF09891.9 KHN69131.1 - 0.024 14.6 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) YrhK PF14145.6 KHN69131.1 - 0.026 14.4 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 YrhK-like protein RINT1_TIP1 PF04437.13 KHN69132.1 - 1.1e-12 47.6 0.3 4.8e-12 45.5 0.3 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Sec20 PF03908.13 KHN69132.1 - 0.34 10.8 5.5 0.28 11.1 3.5 2.0 2 0 0 2 2 2 0 Sec20 ATG16 PF08614.11 KHN69132.1 - 5.3 7.2 9.1 9.1 6.5 9.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ribosomal_L18A PF01775.17 KHN69133.1 - 4.5e-29 101.0 0.1 5.7e-29 100.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Na_Ca_ex_C PF16494.5 KHN69133.1 - 0.052 14.0 0.1 0.077 13.5 0.1 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain HEAT_2 PF13646.6 KHN69134.1 - 0.00024 21.4 0.0 0.00075 19.8 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 KHN69134.1 - 0.00034 20.7 14.1 0.0084 16.2 0.9 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF1442 PF07279.11 KHN69134.1 - 0.093 12.0 0.3 0.18 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) DNA_primase_S PF01896.19 KHN69136.1 - 1.5e-39 135.9 1.1 1.9e-39 135.5 1.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit EamA PF00892.20 KHN69137.1 - 2.9e-06 27.5 31.6 0.0039 17.4 6.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family RNA_pol_Rbc25 PF08292.12 KHN69138.1 - 1.8e-13 50.9 1.8 3.2e-11 43.6 0.1 2.4 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KHN69138.1 - 6.7e-06 26.4 0.1 1.2e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PcfK PF14058.6 KHN69139.1 - 0.015 15.6 0.3 0.95 9.8 0.1 2.5 3 0 0 3 3 3 0 PcfK-like protein Tubulin PF00091.25 KHN69140.1 - 2.6e-64 217.0 0.0 7.8e-64 215.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KHN69140.1 - 1.8e-16 60.4 0.0 3.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KHN69140.1 - 4.8e-05 23.1 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KHN69140.1 - 0.00017 21.9 0.0 0.0008 19.7 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain DUF1702 PF08012.11 KHN69141.1 - 0.069 12.0 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) Clat_adaptor_s PF01217.20 KHN69141.1 - 0.1 12.5 2.6 0.18 11.7 2.6 1.4 1 1 0 1 1 1 0 Clathrin adaptor complex small chain Rer1 PF03248.13 KHN69143.1 - 1.7e-49 167.8 8.3 1.9e-49 167.7 8.3 1.0 1 0 0 1 1 1 1 Rer1 family Halogen_Hydrol PF10112.9 KHN69143.1 - 0.17 11.9 1.3 7.1 6.6 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2809 PF10990.8 KHN69143.1 - 0.23 12.1 6.6 0.4 11.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2809) DUF5092 PF17010.5 KHN69145.1 - 2.7e-60 203.0 2.2 3.7e-60 202.5 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5092) HTH_Bact PF18768.1 KHN69145.1 - 0.0063 16.1 0.2 0.027 14.0 0.2 2.1 1 0 0 1 1 1 1 Helix-turn-helix bacterial domain Ras PF00071.22 KHN69146.1 - 1.7e-56 190.3 1.1 2e-56 190.1 1.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN69146.1 - 1.6e-31 109.0 0.3 2.8e-31 108.2 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN69146.1 - 2.2e-14 53.3 0.1 2.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KHN69146.1 - 1.4e-05 24.5 0.1 1.8e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KHN69146.1 - 3.3e-05 23.9 0.0 4.7e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KHN69146.1 - 0.0013 18.7 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KHN69146.1 - 0.0019 17.7 0.1 0.0093 15.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF3787 PF12655.7 KHN69146.1 - 0.13 12.2 0.8 7.4 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) ParA PF10609.9 KHN69147.1 - 8.8e-60 202.2 0.3 1e-59 202.0 0.3 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 KHN69147.1 - 5.7e-10 39.4 0.6 6e-09 36.1 0.6 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 KHN69147.1 - 7.2e-08 32.5 0.0 8.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KHN69147.1 - 1.8e-06 27.4 2.8 9.9e-06 24.9 2.3 2.3 1 1 1 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KHN69147.1 - 0.0025 17.3 0.1 0.0043 16.5 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 KHN69147.1 - 0.0025 17.1 0.0 0.0039 16.5 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 KHN69147.1 - 0.01 15.3 0.3 0.098 12.1 0.2 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ ERCC4 PF02732.15 KHN69148.1 - 1e-11 45.3 0.5 2.2e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 ERCC4 domain RNA_pol_Rpb4 PF03874.16 KHN69149.1 - 8e-13 48.8 0.1 2e-12 47.5 0.1 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 OGG_N PF07934.12 KHN69150.1 - 6e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KHN69150.1 - 1.2e-05 25.7 0.0 0.00017 22.0 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KHN69150.1 - 0.031 14.2 0.1 0.064 13.2 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif CpXC PF14353.6 KHN69150.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 CpXC protein vATP-synt_E PF01991.18 KHN69151.1 - 0.099 12.0 0.1 0.099 12.0 0.1 1.8 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF5092 PF17010.5 KHN69152.1 - 6.2e-29 101.0 4.0 1.2e-28 100.1 4.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5092) DUF2207 PF09972.9 KHN69152.1 - 0.058 12.2 0.1 0.073 11.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SRP19 PF01922.17 KHN69153.1 - 9.9e-20 71.3 0.0 1.2e-19 71.0 0.0 1.4 1 1 0 1 1 1 1 SRP19 protein Na_Ca_ex PF01699.24 KHN69154.1 - 1.7e-05 24.9 12.3 1.7e-05 24.9 12.3 3.0 2 1 1 3 3 3 1 Sodium/calcium exchanger protein Cytochrom_B558a PF05038.13 KHN69154.1 - 2 7.9 4.5 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Ribosomal_L4 PF00573.22 KHN69155.1 - 6.4e-36 123.8 0.9 8.2e-36 123.5 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KHN69155.1 - 0.0029 17.6 1.0 0.025 14.6 0.0 2.7 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain TPR_11 PF13414.6 KHN69156.1 - 1.7e-08 34.0 0.0 0.0023 17.6 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 KHN69156.1 - 6e-07 29.1 6.6 0.12 12.5 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KHN69156.1 - 2.9e-05 24.3 0.0 0.067 13.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KHN69156.1 - 5.5e-05 22.8 8.4 0.032 14.1 0.0 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69156.1 - 6.6e-05 22.8 5.6 0.011 15.9 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KHN69156.1 - 0.059 13.4 0.2 2.2 8.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KHN69156.1 - 0.14 12.6 0.1 1.5 9.4 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF643 PF04867.12 KHN69156.1 - 0.51 11.0 5.0 0.84 10.3 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF643) CAF1 PF04857.20 KHN69157.1 - 1.3e-17 63.9 1.7 1.8e-09 37.2 0.0 2.6 1 1 1 2 2 2 2 CAF1 family ribonuclease UQ_con PF00179.26 KHN69158.1 - 1.8e-36 124.9 0.0 2.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KHN69158.1 - 0.0024 17.7 1.2 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 UEV domain Ribosomal_S4e PF00900.20 KHN69159.1 - 4.2e-19 68.2 0.0 6.6e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 KHN69159.1 - 6.5e-17 61.4 3.9 1.6e-16 60.1 3.9 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KHN69159.1 - 0.00014 21.5 0.1 0.0004 20.0 0.0 1.8 2 0 0 2 2 2 1 S4 domain 40S_S4_C PF16121.5 KHN69159.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus HhH-GPD PF00730.25 KHN69160.1 - 4e-20 72.3 0.0 5.4e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KHN69160.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2400 PF09674.10 KHN69160.1 - 0.046 13.7 0.4 0.4 10.6 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) EndIII_4Fe-2S PF10576.9 KHN69160.1 - 1.9 8.9 9.0 0.4 11.1 5.5 1.7 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Kinesin PF00225.23 KHN69161.1 - 3.7e-84 282.5 1.8 5.2e-84 282.0 1.8 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KHN69161.1 - 7.3e-25 87.6 0.3 1.4e-24 86.7 0.3 1.5 1 0 0 1 1 1 1 Microtubule binding DivIC PF04977.15 KHN69161.1 - 0.047 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator IF4E PF01652.18 KHN69162.1 - 4.4e-31 107.8 1.3 5.4e-31 107.5 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GYF_2 PF14237.6 KHN69163.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 GYF domain 2 cNMP_binding PF00027.29 KHN69165.1 - 5.8e-17 61.6 0.3 3.8e-16 58.9 0.1 2.4 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Peptidase_S49_N PF08496.10 KHN69166.1 - 0.029 14.4 0.5 0.029 14.4 0.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rad21_Rec8 PF04824.16 KHN69167.1 - 1.3e-06 27.6 0.0 2.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF4276 PF14103.6 KHN69167.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Sbi-IV PF11621.8 KHN69167.1 - 0.096 13.1 0.2 0.19 12.1 0.2 1.5 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI HSF_DNA-bind PF00447.17 KHN69168.1 - 1.5e-28 99.2 2.0 2.5e-28 98.5 2.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding PD40 PF07676.12 KHN69168.1 - 0.14 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat GLTSCR1 PF15249.6 KHN69169.1 - 7.9e-05 23.0 0.7 0.00019 21.8 0.7 1.8 1 1 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein PHF5 PF03660.14 KHN69170.1 - 1.2e-15 57.6 15.1 1.5e-15 57.3 15.1 1.0 1 0 0 1 1 1 1 PHF5-like protein Prok-RING_4 PF14447.6 KHN69170.1 - 0.15 11.9 19.4 0.15 12.0 6.7 3.3 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 SNRNP27 PF08648.12 KHN69171.1 - 0.077 13.1 0.5 0.24 11.5 0.5 1.8 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins DUF1892 PF08987.10 KHN69171.1 - 0.082 13.1 0.2 0.082 13.1 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1892) Spc7 PF08317.11 KHN69173.1 - 5.7e-12 45.2 21.4 1.1e-11 44.1 17.7 2.7 3 0 0 3 3 3 1 Spc7 kinetochore protein T3SSipB PF16535.5 KHN69173.1 - 0.21 12.1 1.3 0.76 10.2 1.0 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB Type2_restr_D3 PF16902.5 KHN69173.1 - 0.22 11.5 6.0 1.3 9.0 2.1 3.0 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain CREPT PF16566.5 KHN69173.1 - 4.9 7.3 10.3 0.46 10.7 4.0 2.5 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Ndc1_Nup PF09531.10 KHN69174.1 - 0.012 14.4 0.3 0.013 14.2 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1447 PF07288.11 KHN69174.1 - 0.043 13.9 0.5 0.078 13.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) Ribosomal_S25 PF03297.15 KHN69176.1 - 1.1e-22 80.1 4.9 1.6e-22 79.6 4.9 1.2 1 0 0 1 1 1 1 S25 ribosomal protein tRNA_synthFbeta PF17759.1 KHN69176.1 - 0.082 12.3 0.6 0.2 11.1 0.4 1.7 1 1 1 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain Ribosomal_S13_N PF08069.12 KHN69178.1 - 2.4e-17 62.7 0.1 4.8e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KHN69178.1 - 1.9e-09 37.6 0.1 2.6e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S25 PF03297.15 KHN69179.1 - 1.1e-22 80.1 4.9 1.6e-22 79.6 4.9 1.2 1 0 0 1 1 1 1 S25 ribosomal protein tRNA_synthFbeta PF17759.1 KHN69179.1 - 0.082 12.3 0.6 0.2 11.1 0.4 1.7 1 1 1 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain DEAD PF00270.29 KHN69180.1 - 4.6e-46 156.8 0.0 9.4e-46 155.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69180.1 - 1.3e-32 112.4 0.0 1.1e-30 106.2 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KHN69180.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KHN69180.1 - 0.0029 17.6 0.0 0.0076 16.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_tran_28_C PF04101.16 KHN69180.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Radical_SAM_C PF16199.5 KHN69181.1 - 2.9e-31 107.3 0.0 7.3e-31 106.0 0.0 1.7 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KHN69181.1 - 1.1e-18 68.1 0.2 4.1e-17 63.1 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KHN69181.1 - 8.2e-09 35.7 0.1 1.9e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KHN69181.1 - 1.5e-05 24.9 0.1 3.6e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KHN69181.1 - 0.001 19.5 0.1 0.0022 18.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KHN69181.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Adaptin_N PF01602.20 KHN69182.1 - 1e-23 83.7 0.8 1e-23 83.7 0.8 2.2 3 0 0 3 3 3 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KHN69182.1 - 7.4e-18 64.8 0.2 2e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KHN69182.1 - 7.2e-17 61.6 0.0 2e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 KHN69182.1 - 5.8e-05 23.2 8.2 0.0015 18.6 0.1 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KHN69182.1 - 0.048 13.9 0.0 0.21 11.9 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat Coatomer_g_Cpla PF16381.5 KHN69182.1 - 0.09 12.9 0.4 0.67 10.1 0.4 2.4 1 1 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KHN69182.1 - 0.094 13.1 0.0 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats DUF760 PF05542.11 KHN69182.1 - 0.16 12.3 0.9 0.62 10.5 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF760) TANGO2 PF05742.12 KHN69182.1 - 0.26 11.3 2.2 0.28 11.2 0.7 1.7 2 0 0 2 2 2 0 Transport and Golgi organisation 2 WD40 PF00400.32 KHN69183.1 - 7.3e-23 80.4 11.4 1.1e-05 26.1 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69183.1 - 3.1e-11 43.4 0.7 0.041 14.2 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KHN69183.1 - 0.0019 16.9 1.2 0.049 12.3 0.5 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.11 KHN69183.1 - 0.0045 16.9 0.1 0.013 15.4 0.1 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KHN69183.1 - 0.0058 17.1 0.0 3.1 8.4 0.0 3.5 3 0 0 3 3 3 1 PQQ-like domain Ge1_WD40 PF16529.5 KHN69183.1 - 0.023 13.7 0.1 2.7 6.9 0.0 2.7 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD_2 PF06733.15 KHN69184.1 - 6.5e-39 133.4 4.1 1.3e-38 132.4 4.1 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 KHN69184.1 - 3.3e-32 112.0 0.1 8.8e-32 110.6 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KHN69184.1 - 5.4e-06 26.5 0.0 0.00013 22.1 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN69184.1 - 0.021 14.6 0.2 0.37 10.5 0.2 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KHN69184.1 - 0.024 14.9 0.1 4.7 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KHN69184.1 - 0.034 13.9 0.4 0.06 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KHN69184.1 - 0.15 11.8 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Brix PF04427.18 KHN69185.1 - 5.1e-17 62.6 0.3 6.5e-17 62.3 0.3 1.1 1 0 0 1 1 1 1 Brix domain HGTP_anticodon PF03129.20 KHN69185.1 - 0.05 13.7 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Anticodon binding domain IHO1 PF15771.5 KHN69185.1 - 0.18 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 adh_short PF00106.25 KHN69187.1 - 1.4e-24 86.7 0.0 1.9e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KHN69187.1 - 5.4e-15 55.6 0.0 9.7e-15 54.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KHN69187.1 - 0.0032 16.7 0.1 0.0041 16.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.15 KHN69187.1 - 0.0041 17.0 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein UDPG_MGDP_dh_N PF03721.14 KHN69187.1 - 0.0045 16.6 0.1 0.011 15.3 0.0 1.6 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RcnB PF11776.8 KHN69187.1 - 0.0099 15.9 0.3 0.021 14.9 0.3 1.6 1 0 0 1 1 1 1 Nickel/cobalt transporter regulator Epimerase PF01370.21 KHN69187.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KHN69187.1 - 0.029 14.9 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KHN69187.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L14 PF00238.19 KHN69188.1 - 3.5e-39 133.7 0.0 4.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Trm112p PF03966.16 KHN69190.1 - 4.7e-08 33.5 0.0 1.3e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Trm112p-like protein zf-C2H2_11 PF16622.5 KHN69190.1 - 0.31 10.8 0.1 0.31 10.8 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type Stc1 PF12898.7 KHN69190.1 - 0.66 10.6 3.3 3.9 8.1 3.3 2.0 1 1 0 1 1 1 0 Stc1 domain WD40 PF00400.32 KHN69191.1 - 1.2e-11 44.9 5.3 3.4e-05 24.5 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69191.1 - 1.7e-05 25.0 0.0 0.32 11.3 0.0 5.1 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 KHN69191.1 - 0.0036 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain RNase_P_p30 PF01876.16 KHN69192.1 - 1.8e-31 109.3 0.0 2.7e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 RNase_P_p30 PF01876.16 KHN69193.1 - 2.1e-23 82.9 0.1 2.3e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 RNase P subunit p30 DUF5101 PF17031.5 KHN69195.1 - 7.3e-34 115.8 8.2 8.2e-34 115.7 8.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) GCK PF07802.11 KHN69195.1 - 0.46 10.9 6.8 0.2 12.1 1.3 2.1 1 1 1 2 2 2 0 GCK domain NAM-associated PF14303.6 KHN69197.1 - 0.065 13.9 0.2 0.095 13.4 0.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DMP12 PF16779.5 KHN69198.1 - 0.091 12.7 0.2 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 DNA-mimic protein CDtoxinA PF03498.14 KHN69198.1 - 0.092 12.3 0.0 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain YmzC PF14157.6 KHN69198.1 - 0.27 11.4 1.5 9.9 6.3 0.1 2.5 2 0 0 2 2 2 0 YmzC-like protein Coatomer_WDAD PF04053.14 KHN69199.1 - 8e-41 140.5 0.3 3.5e-39 135.1 0.1 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 KHN69199.1 - 2.8e-30 103.9 15.4 1.3e-06 29.0 0.3 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 KHN69199.1 - 0.027 13.1 0.2 1.3 7.6 0.1 3.0 4 1 1 5 5 5 0 Nucleoporin Nup120/160 TPR_1 PF00515.28 KHN69199.1 - 0.036 13.9 0.9 8.3 6.4 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 KHN69199.1 - 0.047 13.6 0.1 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.17 KHN69199.1 - 2.3 8.5 5.6 22 5.5 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 KHN69200.1 - 6.2e-11 42.7 4.9 0.0012 19.6 0.3 5.0 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69200.1 - 0.00045 20.5 0.0 3.3 8.1 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KHN69200.1 - 0.0035 17.8 0.2 3.5 8.2 0.0 4.3 5 0 0 5 5 5 1 PQQ-like domain HPS3_N PF14761.6 KHN69200.1 - 0.044 13.3 0.0 14 5.2 0.0 2.9 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Lactonase PF10282.9 KHN69200.1 - 0.11 11.8 0.0 0.28 10.4 0.0 1.8 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller MMR_HSR1_Xtn PF16897.5 KHN69201.1 - 3.4e-36 123.5 1.5 5.9e-36 122.7 1.5 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KHN69201.1 - 5.8e-19 67.9 0.0 1.2e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KHN69201.1 - 1.7e-18 66.7 0.0 4.1e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KHN69201.1 - 7.7e-11 41.8 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KHN69201.1 - 0.018 14.0 0.3 0.13 11.3 0.0 2.3 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KHN69201.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KHN69201.1 - 0.026 14.7 0.0 0.068 13.4 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KHN69201.1 - 0.048 14.1 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KHN69201.1 - 0.059 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KHN69201.1 - 0.06 13.4 1.9 3.5 7.7 0.0 2.5 2 1 1 3 3 3 0 Dynamin family AAA_28 PF13521.6 KHN69201.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KHN69201.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prenyltrans PF00432.21 KHN69203.1 - 2.8e-44 148.5 8.2 8e-13 47.9 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KHN69203.1 - 3.6e-05 23.0 0.0 0.4 9.7 0.0 3.6 1 1 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KHN69203.1 - 0.13 11.3 0.1 2.6 7.0 0.0 2.6 2 2 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain TLC PF03219.14 KHN69204.1 - 3.9e-45 154.5 32.5 4.9e-45 154.2 32.5 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Glycophorin_A PF01102.18 KHN69204.1 - 1.1 9.5 3.2 4.7 7.5 0.0 3.2 2 1 1 3 3 3 0 Glycophorin A Vma12 PF11712.8 KHN69204.1 - 2.5 8.2 7.3 4.4 7.4 0.6 3.1 3 1 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2244 PF10003.9 KHN69205.1 - 4.9 6.8 5.4 7.9 6.1 5.4 1.5 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) TFIIS_C PF01096.18 KHN69206.1 - 4.3e-16 58.5 1.4 4.3e-16 58.5 1.4 2.9 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) DUF3797 PF12677.7 KHN69206.1 - 0.0011 18.8 0.6 0.0011 18.8 0.6 2.3 3 1 1 4 4 4 1 Domain of unknown function (DUF3797) zf-RING_4 PF14570.6 KHN69206.1 - 0.0021 17.8 6.2 0.22 11.3 0.1 3.3 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain tRNA-synt_1f PF01921.18 KHN69206.1 - 0.013 14.5 3.4 0.15 10.9 0.8 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (K) Zn_ribbon_SprT PF17283.2 KHN69206.1 - 0.057 13.3 10.4 4.9 7.2 0.7 3.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain CpXC PF14353.6 KHN69206.1 - 0.094 12.8 4.2 0.22 11.6 4.3 1.6 1 1 0 1 1 1 0 CpXC protein CGGC PF08821.11 KHN69206.1 - 0.13 12.5 5.8 0.15 12.2 5.8 1.1 1 0 0 1 1 1 0 CGGC domain DUF951 PF06107.11 KHN69206.1 - 0.35 10.8 4.8 0.47 10.4 0.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) IBR PF01485.21 KHN69206.1 - 0.7 10.2 9.0 1.4 9.2 2.2 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Mu-like_Com PF10122.9 KHN69206.1 - 4.3 6.9 0.0 4.3 6.9 0.0 3.1 1 1 1 3 3 3 0 Mu-like prophage protein Com TPR_2 PF07719.17 KHN69207.1 - 9.6e-12 44.1 4.3 0.59 10.4 0.0 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69207.1 - 4.6e-11 42.0 16.7 0.023 14.9 0.0 7.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KHN69207.1 - 9.3e-11 41.1 8.8 0.019 14.8 0.1 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 KHN69207.1 - 3.9e-09 37.0 0.0 2 9.1 0.0 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KHN69207.1 - 3.9e-08 33.5 0.5 15 5.9 0.0 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KHN69207.1 - 1e-06 29.1 0.0 0.25 11.9 0.0 4.4 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KHN69207.1 - 1.2e-06 28.8 1.6 1.8 9.4 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KHN69207.1 - 8.2e-06 26.0 0.7 0.1 12.8 0.6 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KHN69207.1 - 6.7e-05 22.5 1.4 7 6.4 0.0 4.5 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 KHN69207.1 - 0.0088 16.8 0.0 22 6.2 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KHN69207.1 - 0.027 13.8 0.0 0.52 9.6 0.0 2.4 2 1 0 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 KHN69207.1 - 0.04 14.0 2.6 13 6.1 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KHN69207.1 - 0.11 12.9 0.3 9.8 6.8 0.1 4.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 KHN69208.1 - 2e-33 115.8 24.1 2.8e-33 115.4 24.1 1.2 1 0 0 1 1 1 1 TLC domain Wzy_C PF04932.15 KHN69208.1 - 6.9 6.3 11.3 3.3 7.3 8.1 1.9 2 0 0 2 2 2 0 O-Antigen ligase Glutaredoxin PF00462.24 KHN69209.1 - 3.3e-10 40.0 0.1 4.4e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KHN69209.1 - 0.00013 22.4 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GATA PF00320.27 KHN69210.1 - 3.9e-17 61.6 3.6 7.1e-17 60.7 3.6 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 KHN69210.1 - 0.024 14.2 0.7 0.068 12.7 0.7 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding TDP43_N PF18694.1 KHN69210.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Transactive response DNA-binding protein N-terminal domain Auto_anti-p27 PF06677.12 KHN69210.1 - 0.08 13.1 0.9 0.36 11.0 0.3 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-RING_2 PF13639.6 KHN69211.1 - 1.1e-12 48.1 8.1 1.8e-12 47.4 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KHN69211.1 - 3.6e-09 36.3 6.2 6.5e-09 35.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KHN69211.1 - 2.9e-08 33.9 8.4 6.7e-08 32.7 8.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KHN69211.1 - 5.8e-08 32.3 6.2 1.1e-07 31.4 6.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KHN69211.1 - 2.1e-07 30.8 4.8 4.1e-07 29.9 4.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KHN69211.1 - 1.2e-06 28.2 5.6 2.1e-06 27.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KHN69211.1 - 6.7e-06 26.0 6.4 1e-05 25.4 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KHN69211.1 - 2.2e-05 24.2 6.5 3.6e-05 23.5 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KHN69211.1 - 0.0012 18.9 5.0 0.0026 17.8 5.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KHN69211.1 - 0.0044 16.8 6.4 0.006 16.4 5.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KHN69211.1 - 0.0046 16.5 6.2 0.0085 15.7 6.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 KHN69211.1 - 0.0054 16.7 1.7 0.016 15.2 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger zinc_ribbon_16 PF17034.5 KHN69211.1 - 0.025 14.8 0.9 0.052 13.8 0.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf_UBZ PF18439.1 KHN69211.1 - 0.042 13.4 0.3 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_4 PF15227.6 KHN69211.1 - 0.066 13.4 4.2 0.18 12.0 4.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KHN69211.1 - 1.2 9.0 5.6 2.6 7.9 5.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KHN69211.1 - 1.3 9.3 6.2 11 6.3 6.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 KHN69211.1 - 1.9 8.4 8.1 4.4 7.3 8.1 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KHN69211.1 - 5.4 7.4 7.6 10 6.5 7.6 1.5 1 0 0 1 1 1 0 RING-like domain Syja_N PF02383.18 KHN69212.1 - 2.7e-41 142.0 0.1 1.2e-39 136.5 0.1 2.1 1 1 0 1 1 1 1 SacI homology domain Ten1 PF12658.7 KHN69213.1 - 0.12 12.3 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit DHHC PF01529.20 KHN69214.1 - 4.9e-28 97.9 13.7 4.9e-28 97.9 13.7 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.25 KHN69214.1 - 0.12 12.9 5.7 0.15 12.7 2.7 2.4 2 0 0 2 2 2 0 Plexin repeat EXS PF03124.14 KHN69215.1 - 2e-50 172.0 29.3 2.9e-50 171.4 29.3 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KHN69215.1 - 4.5e-08 33.4 10.3 2.8e-05 24.2 0.0 2.7 1 1 1 2 2 2 2 SPX domain TRM PF02005.16 KHN69216.1 - 1.2e-92 311.0 3.9 1.7e-92 310.5 3.9 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 KHN69216.1 - 0.00017 21.4 0.6 0.00041 20.2 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KHN69216.1 - 0.00029 20.4 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KHN69216.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 0 Met-10+ like-protein TerY_C PF15616.6 KHN69216.1 - 0.038 14.1 0.8 0.038 14.1 0.8 1.9 2 0 0 2 2 2 0 TerY-C metal binding domain Methyltransf_16 PF10294.9 KHN69216.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Methyltr_RsmB-F PF01189.17 KHN69216.1 - 0.12 11.9 0.5 0.41 10.2 0.0 2.0 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 KHN69216.1 - 0.13 13.0 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KHN69218.1 - 7e-64 215.7 0.1 1.3e-63 214.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69218.1 - 1.2e-33 116.5 0.0 1.7e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69218.1 - 6.6e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KHN69218.1 - 0.0014 18.2 0.1 0.0051 16.4 0.2 1.8 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 KHN69218.1 - 0.0072 15.9 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 KHN69218.1 - 0.037 13.6 0.4 1.7 8.2 0.1 2.8 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KHN69218.1 - 0.049 13.0 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KHN69218.1 - 0.063 13.2 0.1 0.097 12.6 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DHHC PF01529.20 KHN69220.1 - 8.9e-15 55.0 13.5 8.9e-15 55.0 13.5 2.4 2 2 0 2 2 2 1 DHHC palmitoyltransferase zf-A20 PF01754.16 KHN69220.1 - 5.8 7.0 7.3 19 5.3 0.1 2.5 2 0 0 2 2 2 0 A20-like zinc finger RRS1 PF04939.12 KHN69221.1 - 7.9e-22 77.9 1.0 9.7e-22 77.6 1.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PolyA_pol_RNAbd PF12627.7 KHN69221.1 - 0.15 11.8 0.4 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A vATP-synt_AC39 PF01992.16 KHN69222.1 - 3.7e-32 112.1 12.3 5.1e-32 111.7 12.3 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Prok-E2_E PF14462.6 KHN69222.1 - 0.088 12.6 0.0 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic E2 family E LRR_5 PF13306.6 KHN69222.1 - 0.52 10.3 4.8 0.28 11.2 0.6 2.4 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF3888 PF13027.6 KHN69223.1 - 0.11 12.9 2.6 5 7.6 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3888) DUF2203 PF09969.9 KHN69224.1 - 0.028 15.1 0.1 0.047 14.4 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) 14-3-3 PF00244.20 KHN69224.1 - 0.057 12.9 0.4 1.6 8.2 0.1 2.1 1 1 1 2 2 2 0 14-3-3 protein Bromodomain PF00439.25 KHN69225.1 - 8.3e-20 70.7 0.5 1.3e-19 70.0 0.5 1.3 1 0 0 1 1 1 1 Bromodomain Ribosomal_L16 PF00252.18 KHN69226.1 - 3.4e-36 124.2 0.1 4.6e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Proteasome PF00227.26 KHN69227.1 - 1.8e-30 105.9 0.2 2.1e-30 105.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit P30 PF07390.11 KHN69227.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Mycoplasma P30 protein Proteasome_A_N PF10584.9 KHN69227.1 - 0.06 13.1 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature TPR_2 PF07719.17 KHN69228.1 - 0.00021 21.2 1.1 0.11 12.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KHN69228.1 - 0.00054 20.4 0.0 0.012 16.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KHN69228.1 - 0.014 16.2 0.1 3.6 8.7 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat NAD_binding_9 PF13454.6 KHN69228.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding ATP13 PF12921.7 KHN69228.1 - 0.09 12.6 0.3 2.6 7.9 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ATPase expression DUF1636 PF07845.11 KHN69228.1 - 0.091 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) SBDS PF01172.18 KHN69230.1 - 1.2e-24 86.2 0.3 2.2e-24 85.3 0.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Semenogelin PF05474.11 KHN69230.1 - 0.0024 16.5 1.2 0.0026 16.4 1.2 1.1 1 0 0 1 1 1 1 Semenogelin Nmad5 PF18757.1 KHN69230.1 - 0.018 15.2 0.8 0.029 14.6 0.8 1.3 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 B12-binding PF02310.19 KHN69230.1 - 0.026 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain DUF327 PF03885.13 KHN69230.1 - 0.029 14.3 2.4 0.86 9.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF327) UBA_2 PF08587.11 KHN69230.1 - 0.05 13.7 1.5 0.17 12.0 0.1 2.5 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) PrgU PF09627.10 KHN69230.1 - 0.091 12.7 0.7 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 PrgU-like protein WD-3 PF09765.9 KHN69230.1 - 0.11 11.8 1.0 0.25 10.6 1.2 1.5 1 1 1 2 2 2 0 WD-repeat region Pkinase PF00069.25 KHN69231.1 - 1.1e-34 120.0 0.0 3e-34 118.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69231.1 - 3.7e-23 82.1 0.0 5.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH_4 PF18044.1 KHN69232.1 - 6.4e-08 32.2 3.0 6.4e-08 32.2 3.0 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KHN69232.1 - 3.3e-07 30.1 6.1 8.4e-07 28.9 6.1 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KHN69232.1 - 9.2e-07 28.6 2.9 1.8e-06 27.7 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KHN69232.1 - 0.043 14.5 1.7 0.043 14.5 1.7 1.8 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KHN69232.1 - 0.24 11.9 4.0 0.48 11.0 4.0 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Bromodomain PF00439.25 KHN69233.1 - 3.2e-51 171.3 0.2 2.9e-25 88.2 0.0 2.7 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 KHN69233.1 - 1.2e-06 28.5 0.1 2.7e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation CTP_transf_like PF01467.26 KHN69233.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Cytidylyltransferase-like PspA_IM30 PF04012.12 KHN69233.1 - 0.025 14.1 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 PspA/IM30 family DUF1192 PF06698.11 KHN69233.1 - 0.093 12.8 0.9 0.28 11.3 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3461 PF11944.8 KHN69233.1 - 0.31 11.2 2.8 2.4 8.3 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3461) Spt4 PF06093.13 KHN69235.1 - 4.8e-30 103.5 0.2 6e-30 103.2 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Cyclin_N PF00134.23 KHN69237.1 - 3.5e-07 30.0 2.1 1.4e-06 28.1 1.7 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KHN69237.1 - 0.0025 18.2 0.7 0.0035 17.7 0.7 1.5 1 1 0 1 1 1 1 Cyclin ArfGap PF01412.18 KHN69238.1 - 3.6e-24 85.1 0.5 6.2e-24 84.3 0.1 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ricin_B_lectin PF00652.22 KHN69239.1 - 0.062 13.6 0.0 0.1 12.8 0.0 1.4 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Lectin_C PF00059.21 KHN69239.1 - 0.14 12.9 0.0 0.24 12.2 0.0 1.3 1 0 0 1 1 1 0 Lectin C-type domain GRDP-like PF07173.12 KHN69240.1 - 0.028 15.1 0.0 0.063 13.9 0.0 1.6 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like GH97_C PF14509.6 KHN69241.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.6 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Tau95 PF09734.9 KHN69242.1 - 6.5e-14 52.9 0.0 1e-13 52.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF1945 PF09178.10 KHN69242.1 - 0.024 14.8 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) Ribosomal_L6e PF01159.19 KHN69243.1 - 1.1e-09 38.9 0.4 0.0001 22.8 0.4 2.3 1 1 1 2 2 2 2 Ribosomal protein L6e Prot_ATP_OB_N PF17758.1 KHN69243.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Thr_synth_N PF14821.6 KHN69243.1 - 0.095 12.9 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Threonine synthase N terminus Pkinase PF00069.25 KHN69244.1 - 6.3e-58 196.2 0.0 7.6e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69244.1 - 2.8e-29 102.2 0.0 3.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69244.1 - 2.1e-09 37.1 0.0 4.7e-09 36.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KHN69244.1 - 6.7e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KHN69244.1 - 0.00013 21.1 0.0 0.00071 18.6 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 KHN69244.1 - 0.024 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 KHN69244.1 - 0.024 14.6 0.1 0.049 13.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KHN69244.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KHN69244.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Nse4_C PF08743.10 KHN69245.1 - 1e-14 54.5 0.1 2.4e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Nse4 C-terminal TBCC PF07986.12 KHN69246.1 - 1.5e-10 40.8 10.5 1.5e-10 40.8 10.5 1.6 1 1 1 2 2 2 1 Tubulin binding cofactor C Diphthami_syn_2 PF01902.17 KHN69247.1 - 1.7e-39 135.6 0.8 4.5e-39 134.2 0.8 1.6 1 1 0 1 1 1 1 Diphthamide synthase tRNA_Me_trans PF03054.16 KHN69247.1 - 0.016 14.0 0.1 0.021 13.6 0.1 1.4 1 0 0 1 1 1 0 tRNA methyl transferase G6PD_C PF02781.16 KHN69248.1 - 5.1e-41 140.8 0.5 8.1e-41 140.1 0.5 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KHN69248.1 - 7.2e-18 65.8 0.0 1.9e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Proteasome PF00227.26 KHN69249.1 - 1.9e-42 144.9 1.1 2.4e-42 144.6 1.1 1.1 1 0 0 1 1 1 1 Proteasome subunit HTH_micro PF17007.5 KHN69250.1 - 2.1e-129 432.3 18.0 3.8e-129 431.5 18.0 1.4 1 0 0 1 1 1 1 HTH-like TFIIE_alpha PF02002.17 KHN69250.1 - 0.00062 19.6 7.1 0.06 13.2 0.1 3.9 4 0 0 4 4 4 2 TFIIE alpha subunit AAA_5 PF07728.14 KHN69251.1 - 9.7e-108 356.0 0.1 1.9e-29 102.5 0.0 8.0 8 0 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KHN69251.1 - 1.5e-27 96.0 0.0 2.8e-09 36.9 0.0 5.2 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KHN69251.1 - 9.2e-21 74.7 1.7 4.8e-06 27.0 0.0 6.6 7 0 0 7 7 5 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KHN69251.1 - 3.7e-16 60.0 4.1 0.00095 19.6 0.0 5.8 6 1 0 6 6 4 4 AAA ATPase domain AAA_7 PF12775.7 KHN69251.1 - 2.2e-14 53.4 0.4 0.059 12.9 0.0 5.1 4 0 0 4 4 4 4 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KHN69251.1 - 7.9e-13 48.4 0.1 1.7e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_6 PF12774.7 KHN69251.1 - 5e-12 45.4 0.8 1.6e-05 24.0 0.0 5.0 5 1 0 5 5 5 2 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 KHN69251.1 - 2.1e-11 43.8 0.0 0.11 12.1 0.0 5.9 5 1 0 5 5 5 1 Sigma-54 interaction domain Dynein_heavy PF03028.15 KHN69251.1 - 2.9e-10 40.2 0.0 0.032 14.3 0.0 5.4 5 0 0 5 5 5 2 Dynein heavy chain region D6 P-loop domain MCM PF00493.23 KHN69251.1 - 3.1e-10 39.5 0.0 0.017 14.3 0.0 4.6 4 0 0 4 4 4 2 MCM P-loop domain AAA_18 PF13238.6 KHN69251.1 - 1.9e-09 38.2 0.3 0.06 13.9 0.0 5.5 4 0 0 4 4 4 2 AAA domain TsaE PF02367.17 KHN69251.1 - 9e-09 35.4 1.4 0.071 13.1 0.0 4.5 4 0 0 4 4 4 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KHN69251.1 - 1.6e-08 34.9 4.4 0.61 10.4 0.0 5.8 6 0 0 6 6 5 3 AAA domain RuvB_N PF05496.12 KHN69251.1 - 3.2e-08 33.5 4.5 0.38 10.5 0.0 5.9 4 3 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KHN69251.1 - 9.5e-08 32.4 0.5 2.5 8.5 0.0 5.5 5 0 0 5 5 4 1 RNA helicase ABC_tran PF00005.27 KHN69251.1 - 1.9e-07 31.7 5.1 1.4 9.4 0.0 5.0 4 0 0 4 4 4 3 ABC transporter Mg_chelatase PF01078.21 KHN69251.1 - 2e-07 30.6 2.1 0.22 10.9 0.0 6.4 7 1 1 8 8 7 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KHN69251.1 - 2.4e-07 30.3 1.2 0.019 14.2 0.0 3.7 3 0 0 3 3 3 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KHN69251.1 - 2.6e-06 27.3 0.2 1.2 8.8 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 KHN69251.1 - 3.4e-06 26.7 3.0 0.037 13.8 0.2 4.4 4 0 0 4 4 4 1 P-loop containing region of AAA domain NACHT PF05729.12 KHN69251.1 - 8.4e-06 25.8 0.9 0.24 11.3 0.0 4.5 4 0 0 4 4 4 1 NACHT domain AAA_lid_7 PF17867.1 KHN69251.1 - 0.00047 20.3 0.1 0.0024 18.0 0.0 2.4 2 0 0 2 2 1 1 Midasin AAA lid domain Roc PF08477.13 KHN69251.1 - 0.00061 20.0 3.3 7 6.9 0.1 4.4 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 KHN69251.1 - 0.00077 19.2 0.2 17 5.0 0.0 4.7 4 1 0 4 4 4 0 AAA domain TniB PF05621.11 KHN69251.1 - 0.0013 18.2 0.3 23 4.3 0.0 4.4 4 0 0 4 4 4 0 Bacterial TniB protein AAA_33 PF13671.6 KHN69251.1 - 0.0016 18.6 0.3 4.1 7.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 KHN69251.1 - 0.0029 16.8 3.5 0.82 8.8 0.1 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KHN69251.1 - 0.004 16.4 0.3 3.4 6.9 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin Rad17 PF03215.15 KHN69251.1 - 0.0059 16.6 0.1 9.2 6.1 0.0 4.0 4 0 0 4 4 3 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KHN69251.1 - 0.0098 16.0 0.0 1.7 8.8 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain CPT PF07931.12 KHN69251.1 - 0.011 15.6 0.2 63 3.3 0.0 5.0 5 0 0 5 5 5 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 KHN69251.1 - 0.017 14.9 0.1 36 4.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain DEAD PF00270.29 KHN69251.1 - 0.044 13.5 0.3 24 4.6 0.0 4.0 4 0 0 4 4 4 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.25 KHN69251.1 - 0.055 13.1 0.0 8.6 6.0 0.0 3.2 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain IPT PF01745.16 KHN69251.1 - 0.091 12.1 0.1 0.88 8.9 0.0 2.5 3 0 0 3 3 3 0 Isopentenyl transferase AAA_25 PF13481.6 KHN69251.1 - 0.099 12.2 1.1 33 4.0 0.0 3.8 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 KHN69251.1 - 0.13 11.3 1.8 6.8 5.7 0.0 3.4 4 0 0 4 4 4 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KHN69251.1 - 0.13 12.2 10.8 6.4 6.7 0.0 5.7 6 0 0 6 6 6 0 RsgA GTPase ResIII PF04851.15 KHN69251.1 - 0.37 10.8 4.6 23 4.9 0.0 4.3 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KHN69251.1 - 0.49 10.7 7.6 21 5.4 0.0 5.4 5 1 0 5 5 5 0 AAA domain NTPase_1 PF03266.15 KHN69251.1 - 0.57 10.1 6.3 3.6 7.5 0.0 4.3 5 1 0 5 5 3 0 NTPase Hpr_kinase_C PF07475.12 KHN69251.1 - 0.6 9.6 4.4 16 5.0 0.1 3.8 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain AAA_11 PF13086.6 KHN69251.1 - 2.4 7.9 5.6 52 3.5 0.0 4.3 4 0 0 4 4 3 0 AAA domain Ribosomal_L23 PF00276.20 KHN69252.1 - 9.3e-14 51.6 2.9 1.8e-13 50.6 2.9 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 adh_short PF00106.25 KHN69252.1 - 0.026 14.0 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.25 KHN69253.1 - 2e-76 256.8 0.0 2.3e-76 256.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69253.1 - 7.7e-33 113.9 0.0 1e-32 113.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KHN69253.1 - 9.7e-06 24.8 0.2 0.00014 21.0 0.2 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KHN69253.1 - 0.00017 21.0 0.0 0.00031 20.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KHN69253.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KHN69253.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KHN69253.1 - 0.02 14.0 0.6 0.045 12.8 0.6 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 Arf PF00025.21 KHN69254.1 - 3.7e-43 147.0 0.0 4.4e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KHN69254.1 - 3e-11 43.6 0.0 5.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KHN69254.1 - 2e-10 40.5 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KHN69254.1 - 6e-09 35.6 0.0 8.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KHN69254.1 - 5.1e-06 26.0 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KHN69254.1 - 1.4e-05 24.4 2.1 0.0002 20.6 0.3 2.6 2 1 1 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 KHN69254.1 - 0.00036 20.5 0.1 0.4 10.6 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KHN69254.1 - 0.00087 19.1 0.1 0.24 11.2 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KHN69254.1 - 0.0029 17.7 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KHN69254.1 - 0.013 15.1 0.1 0.052 13.1 0.0 1.8 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 KHN69254.1 - 0.041 13.5 0.2 9.5 5.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 KHN69254.1 - 0.054 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KHN69254.1 - 0.056 13.8 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KHN69254.1 - 0.071 13.4 0.0 0.69 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain Pkinase_fungal PF17667.1 KHN69255.1 - 0.31 9.8 3.9 0.52 9.0 3.9 1.3 1 0 0 1 1 1 0 Fungal protein kinase SAPS PF04499.15 KHN69255.1 - 6 5.5 14.7 11 4.6 14.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 KHN69255.1 - 7.1 5.1 11.6 12 4.3 11.6 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 KHN69256.1 - 2.4e-50 171.3 0.0 7.5e-50 169.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69256.1 - 2.6e-21 76.1 0.0 4.3e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KHN69256.1 - 0.00018 20.4 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KHN69256.1 - 0.00055 19.3 0.0 2.3 7.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 KHN69256.1 - 0.0032 16.8 0.1 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KHN69256.1 - 0.027 14.0 0.2 0.044 13.4 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KHN69256.1 - 0.032 14.2 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.29 KHN69257.1 - 2e-46 157.7 0.0 3.9e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KHN69257.1 - 1.6e-09 37.6 0.2 6.6e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KHN69257.1 - 4.3e-09 36.0 0.0 8.2e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KHN69257.1 - 2.3e-08 34.3 0.0 6.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KHN69257.1 - 5.8e-08 32.8 0.1 1.8e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KHN69257.1 - 2e-07 31.5 0.1 3e-05 24.5 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 KHN69257.1 - 1.2e-05 25.9 0.0 4.1e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN69257.1 - 1.8e-05 25.0 1.4 0.0051 17.1 1.4 2.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KHN69257.1 - 5e-05 23.3 0.2 0.00059 19.8 0.0 2.5 3 0 0 3 3 3 1 NTPase DUF815 PF05673.13 KHN69257.1 - 5.3e-05 22.5 0.0 8.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KHN69257.1 - 0.00026 20.8 0.0 0.0006 19.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KHN69257.1 - 0.00072 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KHN69257.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KHN69257.1 - 0.0012 19.2 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KHN69257.1 - 0.0015 18.6 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KHN69257.1 - 0.0025 18.1 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KHN69257.1 - 0.0025 17.5 0.0 0.0095 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KHN69257.1 - 0.0034 16.6 0.0 0.013 14.7 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 KHN69257.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KHN69257.1 - 0.0044 16.5 0.1 0.23 10.8 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein Mg_chelatase PF01078.21 KHN69257.1 - 0.0056 16.1 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KHN69257.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KHN69257.1 - 0.0066 16.0 0.0 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KHN69257.1 - 0.0077 16.0 0.1 0.088 12.5 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KHN69257.1 - 0.01 15.8 0.1 0.1 12.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KHN69257.1 - 0.011 15.7 0.7 0.23 11.4 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KHN69257.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 KHN69257.1 - 0.022 14.0 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KHN69257.1 - 0.027 14.8 0.2 0.081 13.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KHN69257.1 - 0.037 14.5 0.1 0.12 12.9 0.0 2.0 2 1 0 2 2 1 0 ABC transporter AAA_25 PF13481.6 KHN69257.1 - 0.039 13.5 1.2 0.36 10.4 0.1 2.2 1 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KHN69257.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 KHN69257.1 - 0.052 13.3 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KHN69257.1 - 0.15 11.2 0.0 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 KHN69257.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF465 PF04325.13 KHN69257.1 - 0.84 9.7 4.5 1.7 8.7 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF1192 PF06698.11 KHN69259.1 - 0.017 15.2 1.3 0.017 15.2 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.8 KHN69259.1 - 0.071 13.1 12.1 0.12 12.4 12.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Nre_C PF04895.12 KHN69259.1 - 0.12 12.3 1.1 0.24 11.3 0.8 1.7 1 1 0 1 1 1 0 Archaeal Nre, C-terminal TMPIT PF07851.13 KHN69259.1 - 0.21 10.8 5.9 0.27 10.5 5.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 KHN69259.1 - 0.33 11.0 7.8 0.42 10.7 7.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KHN69259.1 - 0.38 11.4 3.7 1 10.0 0.5 2.3 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 KHN69259.1 - 0.57 10.0 4.4 2.6 7.9 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 KHN69259.1 - 0.69 9.7 9.7 0.98 9.2 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) LMBR1 PF04791.16 KHN69259.1 - 0.91 8.4 2.6 1 8.2 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-H PF05837.12 KHN69259.1 - 4.2 7.8 9.9 1.8 9.0 7.9 1.4 2 0 0 2 2 1 0 Centromere protein H (CENP-H) DUF3782 PF12644.7 KHN69259.1 - 6.4 7.0 7.5 83 3.4 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3782) XhlA PF10779.9 KHN69259.1 - 9.4 6.5 10.9 8.7 6.6 1.5 2.4 1 1 0 2 2 2 0 Haemolysin XhlA Ribosomal_L11_N PF03946.14 KHN69260.1 - 1.7e-16 59.8 0.0 3.6e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KHN69260.1 - 3.1e-16 59.6 1.0 5e-16 59.0 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Tim29 PF10171.9 KHN69260.1 - 0.15 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 RseC_MucC PF04246.12 KHN69264.1 - 0.048 13.6 0.2 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EMP24_GP25L PF01105.24 KHN69264.1 - 0.12 12.3 3.6 0.15 12.0 0.4 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1282 PF06930.12 KHN69264.1 - 0.72 9.6 16.5 2 8.2 0.6 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Mpv17_PMP22 PF04117.12 KHN69264.1 - 7.1 6.9 9.0 47 4.3 9.0 2.2 1 1 0 1 1 1 0 Mpv17 / PMP22 family Trans_coact PF16805.5 KHN69266.1 - 0.0061 16.6 0.1 0.0061 16.6 0.1 3.0 4 0 0 4 4 4 1 Phage late-transcription coactivator LRR_4 PF12799.7 KHN69267.1 - 6.1e-24 83.7 42.4 1.8e-06 28.1 0.4 7.5 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KHN69267.1 - 7e-10 38.5 1.9 0.00045 19.9 0.2 6.7 2 2 5 7 7 7 4 Leucine rich repeat CDC45 PF02724.14 KHN69268.1 - 0.013 13.8 2.2 0.017 13.5 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein VanZ PF04892.12 KHN69268.1 - 0.017 15.8 2.9 0.051 14.2 1.0 2.2 2 1 0 2 2 2 0 VanZ like family Connexin PF00029.19 KHN69268.1 - 0.024 14.4 3.8 0.028 14.2 1.8 2.1 1 1 0 1 1 1 0 Connexin PTPRCAP PF15713.5 KHN69268.1 - 0.027 14.8 3.7 0.038 14.3 3.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF1129 PF06570.11 KHN69268.1 - 0.046 13.2 0.8 0.046 13.2 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) NPR3 PF03666.13 KHN69268.1 - 0.061 12.1 2.6 0.077 11.8 2.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GET2 PF08690.10 KHN69268.1 - 0.075 12.7 8.4 0.0092 15.7 3.1 1.9 1 1 1 2 2 2 0 GET complex subunit GET2 DUF3464 PF11947.8 KHN69268.1 - 0.075 12.8 1.2 0.15 11.8 0.9 1.7 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3899 PF13038.6 KHN69268.1 - 0.13 12.8 4.8 18 5.9 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) DUF805 PF05656.14 KHN69268.1 - 0.37 11.2 10.1 6.7 7.2 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Zip PF02535.22 KHN69268.1 - 0.69 9.1 5.1 1.1 8.5 5.1 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1430 PF07242.11 KHN69268.1 - 1.5 9.1 17.1 2.8 8.2 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) Orf78 PF06024.12 KHN69268.1 - 6.1 7.2 15.4 0.19 12.0 3.5 3.3 3 1 0 3 3 2 0 Orf78 (ac78) Sec62 PF03839.16 KHN69268.1 - 6.4 6.2 11.2 0.051 13.1 2.9 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 Renin_r PF07850.14 KHN69268.1 - 6.9 7.3 8.3 0.72 10.5 0.4 2.7 2 2 0 2 2 2 0 Renin receptor-like protein U3_assoc_6 PF08640.11 KHN69269.1 - 5.5e-23 80.8 9.3 2.7e-21 75.4 7.8 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 RNA_pol_Rpb1_5 PF04998.17 KHN69270.1 - 9.2e-84 281.0 2.3 2e-83 279.9 2.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KHN69270.1 - 1.4e-70 236.8 0.1 2.6e-70 236.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KHN69270.1 - 1.6e-70 237.9 3.5 1.6e-70 237.9 1.7 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KHN69270.1 - 1.1e-32 113.2 0.0 3.3e-32 111.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KHN69270.1 - 1.5e-27 95.7 0.3 3.6e-27 94.4 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 NIF3 PF01784.18 KHN69271.1 - 1.1e-39 136.6 0.6 3.5e-39 134.9 0.6 1.6 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) LPD13 PF18825.1 KHN69271.1 - 0.0055 16.5 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 13 DS PF01916.17 KHN69271.1 - 0.0058 15.9 1.3 0.77 8.9 0.0 2.1 1 1 1 2 2 2 2 Deoxyhypusine synthase Ribosomal_60s PF00428.19 KHN69272.1 - 1.6e-08 35.0 6.2 2.4e-08 34.4 6.3 1.3 1 1 0 1 1 1 1 60s Acidic ribosomal protein zf-RRPl_C4 PF17026.5 KHN69273.1 - 3.3e-30 104.4 24.3 3.3e-30 104.4 24.3 1.9 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type DUF3795 PF12675.7 KHN69273.1 - 2.1 8.8 17.5 4.6 7.7 17.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) PHF5 PF03660.14 KHN69273.1 - 9.2 6.5 18.3 4.1 7.7 7.5 2.3 1 1 1 2 2 2 0 PHF5-like protein ASF1_hist_chap PF04729.13 KHN69274.1 - 1.9e-30 105.8 0.1 3.5e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone TLP-20 PF06088.11 KHN69274.1 - 0.0039 17.1 0.4 0.0039 17.1 0.4 1.8 2 1 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WIF PF02019.18 KHN69274.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 WIF domain Chromo_2 PF18704.1 KHN69274.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.5 2 1 0 2 2 2 0 Chromatin organization modifier domain 2 Nop14 PF04147.12 KHN69274.1 - 0.46 8.6 19.4 0.7 8.0 19.4 1.3 1 0 0 1 1 1 0 Nop14-like family ASTN_2_hairpin PF18577.1 KHN69275.1 - 0.11 12.7 0.4 0.88 9.7 0.1 2.5 1 1 1 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain SGL PF08450.12 KHN69276.1 - 0.019 14.5 0.1 19 4.7 0.0 3.0 2 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region BBS1 PF14779.6 KHN69276.1 - 0.025 14.0 0.2 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 WD40 PF00400.32 KHN69276.1 - 0.13 13.1 0.1 27 5.9 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat His_Phos_2 PF00328.22 KHN69277.1 - 1.9e-18 67.0 0.0 1.6e-13 50.8 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-HC5HC2H PF13771.6 KHN69277.1 - 0.00039 20.6 1.2 0.0016 18.7 0.3 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KHN69277.1 - 0.026 14.7 1.4 0.074 13.2 0.4 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain VWC PF00093.18 KHN69277.1 - 0.18 12.1 4.5 0.88 9.9 1.3 2.3 2 0 0 2 2 2 0 von Willebrand factor type C domain AAA PF00004.29 KHN69278.1 - 1.1e-44 152.1 0.0 2.3e-44 151.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN69278.1 - 6.4e-11 41.9 0.1 1.6e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KHN69278.1 - 4e-09 36.3 0.1 1.1e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KHN69278.1 - 2.4e-08 34.3 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KHN69278.1 - 2.4e-07 30.7 0.0 5.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KHN69278.1 - 1.6e-06 28.6 0.0 0.00063 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KHN69278.1 - 1.2e-05 25.4 1.4 4.5e-05 23.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KHN69278.1 - 4.9e-05 23.6 1.3 0.03 14.6 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KHN69278.1 - 0.00024 21.7 1.6 0.013 16.1 0.1 3.4 2 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KHN69278.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 KHN69278.1 - 0.0055 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KHN69278.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KHN69278.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 KHN69278.1 - 0.013 14.7 0.1 0.027 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KHN69278.1 - 0.018 14.3 0.7 0.037 13.2 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_24 PF13479.6 KHN69278.1 - 0.02 14.6 0.1 0.073 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 KHN69278.1 - 0.05 13.0 1.1 0.14 11.5 0.1 2.1 2 1 1 3 3 3 0 KaiC RNA_helicase PF00910.22 KHN69278.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KHN69278.1 - 0.072 12.8 0.0 0.23 11.2 0.0 1.9 3 0 0 3 3 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KHN69278.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KHN69278.1 - 0.091 12.7 0.0 0.88 9.5 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KHN69278.1 - 0.095 12.0 0.1 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 KHN69278.1 - 0.31 10.8 2.2 0.43 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain Nup35_RRM PF05172.13 KHN69279.1 - 1.4e-05 25.0 0.0 0.00023 21.1 0.0 2.3 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 KHN69279.1 - 0.00037 20.4 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TFIIE_alpha PF02002.17 KHN69280.1 - 1.4e-18 66.7 8.3 4.2e-18 65.1 8.3 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Mitovir_RNA_pol PF05919.11 KHN69280.1 - 0.24 10.5 4.6 0.32 10.1 4.6 1.5 1 1 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TFIIE-A_C PF11521.8 KHN69280.1 - 0.28 11.5 11.5 1 9.7 11.5 2.0 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Tim17 PF02466.19 KHN69282.1 - 3.8e-07 30.5 4.4 1.9e-05 25.0 4.4 2.7 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Sec8_exocyst PF04048.14 KHN69283.1 - 1.1e-08 35.1 0.8 2.9e-08 33.7 0.2 2.1 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain RFC1 PF08519.12 KHN69283.1 - 0.034 14.3 0.6 0.14 12.3 0.2 2.3 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain NTP_transf_2 PF01909.23 KHN69283.1 - 0.038 14.3 0.7 1.8 8.9 0.3 2.7 2 0 0 2 2 2 0 Nucleotidyltransferase domain Bac_RepA_C PF18008.1 KHN69283.1 - 0.082 13.3 1.2 1.1 9.6 0.5 3.2 2 0 0 2 2 2 0 Replication initiator protein A C-terminal domain HSCB_C PF07743.13 KHN69283.1 - 4.2 7.9 10.1 0.26 11.8 1.5 3.6 5 0 0 5 5 5 0 HSCB C-terminal oligomerisation domain RasGEF PF00617.19 KHN69284.1 - 5.2e-07 30.0 0.2 8.9e-07 29.3 0.2 1.5 1 1 0 1 1 1 1 RasGEF domain LolA PF03548.15 KHN69284.1 - 0.034 13.8 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA WD40 PF00400.32 KHN69285.1 - 0.13 13.2 0.7 17 6.5 0.0 3.5 3 2 1 4 4 4 0 WD domain, G-beta repeat UBA PF00627.31 KHN69286.1 - 6.2e-09 35.6 0.0 6.2e-09 35.6 0.0 2.2 3 0 0 3 3 3 1 UBA/TS-N domain ubiquitin PF00240.23 KHN69286.1 - 0.00014 21.5 0.8 0.00025 20.7 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin family HOIP-UBA PF16678.5 KHN69286.1 - 0.0023 17.9 0.1 0.074 13.1 0.1 2.5 2 0 0 2 2 2 1 HOIP UBA domain pair Ubiquitin_2 PF14560.6 KHN69286.1 - 0.012 16.0 0.6 0.024 15.1 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_4 PF14555.6 KHN69286.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain Metalloenzyme PF01676.18 KHN69287.1 - 3.6e-07 29.8 0.1 5.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 KHN69287.1 - 6.7e-07 29.2 0.4 4.7e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Methyltr_RsmB-F PF01189.17 KHN69288.1 - 1.2e-27 96.8 0.0 2.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 KHN69288.1 - 0.0048 16.7 0.0 0.0089 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KHN69288.1 - 0.025 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KHN69288.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GCD14 PF08704.10 KHN69288.1 - 0.089 12.5 0.0 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KHN69288.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.18 KHN69288.1 - 0.13 12.0 0.6 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 DNA methylase zf-RING_2 PF13639.6 KHN69289.1 - 2.2e-12 47.1 12.2 3.6e-12 46.4 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KHN69289.1 - 8e-10 38.3 6.5 1.5e-09 37.4 6.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KHN69289.1 - 5.8e-07 29.3 12.6 9.8e-07 28.6 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KHN69289.1 - 8.3e-07 28.7 12.4 1.4e-06 28.1 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KHN69289.1 - 6.9e-06 26.3 12.1 1.9e-05 24.9 12.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KHN69289.1 - 0.0017 18.2 11.3 0.0028 17.6 11.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KHN69289.1 - 0.0031 17.5 7.1 0.0093 16.0 7.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KHN69289.1 - 0.0032 17.3 10.4 0.005 16.7 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KHN69289.1 - 0.0058 16.6 4.5 0.0058 16.6 4.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KHN69289.1 - 0.036 13.7 8.5 0.058 13.0 8.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KHN69289.1 - 0.045 13.9 9.3 0.12 12.5 9.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KHN69289.1 - 0.1 12.8 9.3 0.25 11.5 9.3 1.7 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 KHN69289.1 - 0.11 12.4 9.9 0.22 11.4 9.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KHN69289.1 - 0.36 10.6 8.8 1 9.2 8.7 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 KHN69289.1 - 0.66 10.3 10.2 1.5 9.2 10.2 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 KHN69289.1 - 1.3 9.2 8.2 3.6 7.8 8.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RRM_1 PF00076.22 KHN69290.1 - 2.2e-25 88.3 2.0 2e-13 49.9 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KHN69290.1 - 0.00022 21.0 0.0 0.091 12.6 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KHN69290.1 - 0.00049 19.7 0.1 0.019 14.5 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KHN69290.1 - 0.0013 18.8 0.3 0.085 12.9 0.0 2.9 3 0 0 3 3 3 1 RNA binding motif DUF4945 PF16303.5 KHN69290.1 - 0.038 13.9 0.2 11 6.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4945) RRM_8 PF11835.8 KHN69290.1 - 0.13 12.5 0.1 0.53 10.5 0.0 1.9 2 0 0 2 2 2 0 RRM-like domain Peptidase_C50 PF03568.17 KHN69291.1 - 2.9e-43 148.5 1.1 2.7e-37 128.8 0.1 2.2 1 1 1 2 2 2 2 Peptidase family C50 DUF167 PF02594.16 KHN69292.1 - 3.3e-22 78.4 1.4 3.9e-22 78.1 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Pkinase PF00069.25 KHN69293.1 - 6.4e-71 238.8 0.0 7.2e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69293.1 - 1.2e-40 139.5 0.0 1.4e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69293.1 - 0.00015 21.2 0.0 0.0004 19.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KHN69293.1 - 0.00065 18.6 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KHN69293.1 - 0.0033 17.0 0.0 0.016 14.8 0.0 1.9 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KHN69293.1 - 0.059 12.3 0.0 0.38 9.7 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain GPP34 PF05719.11 KHN69294.1 - 1.1e-13 51.7 0.0 1.3e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) RNase_T PF00929.24 KHN69295.1 - 1.5e-08 35.4 0.0 3.1e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Exonuclease EppA_BapA PF07268.11 KHN69295.1 - 0.047 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) DNA_pol_A_exo1 PF01612.20 KHN69295.1 - 0.069 12.9 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 3'-5' exonuclease SMC_N PF02463.19 KHN69296.1 - 2.9e-21 76.0 3.0 8.6e-21 74.4 3.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KHN69296.1 - 4e-08 34.0 31.3 4e-08 34.0 31.3 4.6 2 2 0 2 2 2 1 AAA domain SMC_hinge PF06470.13 KHN69296.1 - 5e-08 33.3 0.1 3.8e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 KHN69296.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KHN69296.1 - 0.0054 16.5 45.2 0.0087 15.8 26.1 3.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KHN69296.1 - 0.0059 16.4 13.4 0.047 13.5 0.4 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 KHN69296.1 - 0.015 15.2 0.6 0.061 13.1 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 KHN69296.1 - 0.035 13.7 0.9 0.18 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KHN69296.1 - 0.83 9.9 4.2 6.3 7.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KHN69296.1 - 0.99 9.9 0.0 0.99 9.9 0.0 5.0 3 2 0 3 3 3 0 ABC transporter Zip PF02535.22 KHN69297.1 - 5.3 6.2 4.2 6.3 5.9 0.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter UCH PF00443.29 KHN69298.1 - 1.1e-33 116.9 0.3 1.6e-33 116.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KHN69298.1 - 1.4e-06 28.1 0.8 5.3e-06 26.3 0.8 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FANCI_HD2 PF14680.6 KHN69298.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FANCI helical domain 2 eIF-5_eIF-2B PF01873.17 KHN69298.1 - 0.97 9.3 4.6 6.4 6.7 0.2 3.0 2 1 1 3 3 3 0 Domain found in IF2B/IF5 cwf18 PF08315.12 KHN69299.1 - 0.012 16.2 9.1 0.72 10.5 5.9 2.5 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor BRCA-2_OB1 PF09103.10 KHN69301.1 - 1.6e-12 47.5 0.0 8.5e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 KHN69301.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.5 1 0 0 1 1 1 1 BRCA2 repeat Pox_T4_C PF04490.12 KHN69301.1 - 0.01 16.0 1.0 3.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Poxvirus T4 protein, C terminus RSN1_7TM PF02714.15 KHN69302.1 - 1.2e-50 172.3 24.3 1.2e-50 172.3 24.3 2.4 3 1 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KHN69302.1 - 1.8e-23 83.1 7.5 1.8e-23 83.1 7.5 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KHN69302.1 - 1e-12 48.7 2.3 1.4e-06 28.7 0.5 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Tmemb_9 PF05434.11 KHN69302.1 - 4.8 7.1 5.5 0.92 9.4 0.4 2.3 2 0 0 2 2 2 0 TMEM9 PgaD PF13994.6 KHN69302.1 - 5.6 7.0 6.5 7.3 6.6 2.6 2.5 1 1 1 2 2 2 0 PgaD-like protein Ribosomal_L7Ae PF01248.26 KHN69304.1 - 4.7e-22 77.5 0.1 5.9e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KHN69304.1 - 0.011 15.8 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF5100 PF17029.5 KHN69305.1 - 5.6e-32 110.3 3.6 6.2e-32 110.1 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5100) PUF PF00806.19 KHN69306.1 - 9.9e-10 37.6 0.1 0.03 14.0 0.0 4.0 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat 3H PF02829.14 KHN69306.1 - 0.046 14.0 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 3H domain MCM PF00493.23 KHN69307.1 - 1.9e-69 233.2 0.0 3.5e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN69307.1 - 5.5e-14 52.1 0.3 1.2e-13 51.1 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KHN69307.1 - 3.8e-13 49.7 0.2 7.9e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 KHN69307.1 - 1.2e-05 25.4 0.0 3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KHN69307.1 - 5.1e-05 22.7 0.4 0.018 14.4 0.0 2.7 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KHN69307.1 - 5.5e-05 22.9 0.2 0.0025 17.5 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KHN69307.1 - 0.0092 16.4 0.2 0.018 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 KHN69307.1 - 0.022 15.3 0.3 0.1 13.1 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 KHN69307.1 - 0.023 14.5 0.0 0.07 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HypA PF01155.19 KHN69307.1 - 0.028 14.4 0.3 0.066 13.2 0.3 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA AAA_19 PF13245.6 KHN69307.1 - 0.03 14.7 0.8 0.75 10.1 0.5 2.4 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KHN69307.1 - 0.04 13.4 0.4 0.094 12.2 0.2 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 KHN69307.1 - 0.048 13.4 0.1 0.13 11.9 0.1 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 KHN69307.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KHN69307.1 - 0.12 12.6 0.2 0.57 10.5 0.2 2.2 1 1 0 1 1 1 0 AAA domain Zn-ribbon_8 PF09723.10 KHN69307.1 - 0.14 12.3 0.3 0.34 11.1 0.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain GFA PF04828.14 KHN69307.1 - 0.28 11.5 1.8 1.6 9.1 1.5 2.2 2 1 1 3 3 2 0 Glutathione-dependent formaldehyde-activating enzyme ADK_lid PF05191.14 KHN69307.1 - 0.62 10.1 2.5 2.1 8.4 2.4 1.9 1 1 1 2 2 2 0 Adenylate kinase, active site lid DUF5090 PF17009.5 KHN69308.1 - 6.9e-39 133.8 14.0 7.7e-39 133.6 14.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5090) DUF962 PF06127.11 KHN69308.1 - 0.013 15.6 2.9 0.045 13.8 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF962) ABC2_membrane_3 PF12698.7 KHN69308.1 - 0.42 9.7 16.0 0.47 9.5 16.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF202 PF02656.15 KHN69308.1 - 9 6.8 7.1 0.35 11.4 0.3 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Sel1 PF08238.12 KHN69309.1 - 1.3e-23 82.9 8.5 7.7e-07 29.6 0.0 6.8 7 0 0 7 7 7 4 Sel1 repeat TPR_6 PF13174.6 KHN69309.1 - 0.069 13.8 1.7 65 4.5 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KHN69310.1 - 3.9e-57 193.6 0.0 4.6e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69310.1 - 9e-32 110.4 0.0 1.1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69310.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KHN69310.1 - 0.00084 19.3 0.0 0.043 13.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KHN69310.1 - 0.059 12.4 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CODH_A_N PF18537.1 KHN69310.1 - 0.077 13.0 0.6 0.93 9.6 0.1 2.4 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Haspin_kinase PF12330.8 KHN69310.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KHN69310.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KHN69310.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KHN69310.1 - 0.17 11.4 0.1 0.4 10.2 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KHN69310.1 - 0.18 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2_TM PF16995.5 KHN69312.1 - 0.02 14.6 1.5 0.026 14.2 1.5 1.3 1 1 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase DUF3671 PF12420.8 KHN69312.1 - 0.037 14.1 0.2 0.059 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function PhoLip_ATPase_C PF16212.5 KHN69312.1 - 0.11 12.2 5.2 0.12 12.1 5.2 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF3792 PF12670.7 KHN69312.1 - 0.11 12.7 8.6 0.14 12.3 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Ninjurin PF04923.12 KHN69312.1 - 0.33 10.9 9.0 0.14 12.1 6.1 1.8 1 1 1 2 2 2 0 Ninjurin GST_C_3 PF14497.6 KHN69313.1 - 0.058 13.6 0.3 1.1 9.5 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2258 PF10015.9 KHN69313.1 - 1.2 9.4 4.9 5.8 7.1 0.2 3.1 3 2 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2258) AIG1 PF04548.16 KHN69315.1 - 3.4e-08 33.1 1.0 8.2e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 KHN69315.1 - 1.6e-06 28.2 0.1 8.4e-06 25.9 0.1 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MFS_1 PF07690.16 KHN69315.1 - 1.7e-06 27.2 0.2 2.5e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RsgA_GTPase PF03193.16 KHN69315.1 - 6.1e-05 23.0 0.4 6.1e-05 23.0 0.4 2.7 2 1 0 2 2 2 1 RsgA GTPase Bax1-I PF01027.20 KHN69315.1 - 0.00068 19.5 8.8 0.001 19.0 8.8 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 AAA_29 PF13555.6 KHN69315.1 - 0.0012 18.6 0.1 0.0032 17.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 KHN69315.1 - 0.0072 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KHN69315.1 - 0.0074 16.7 0.0 0.02 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain Dynamin_N PF00350.23 KHN69315.1 - 0.0083 16.2 0.1 0.0083 16.2 0.1 4.1 4 3 2 6 6 6 1 Dynamin family ABC_tran PF00005.27 KHN69315.1 - 0.0089 16.5 3.7 0.019 15.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter 7TMR-DISM_7TM PF07695.11 KHN69315.1 - 0.01 15.8 4.8 0.017 15.0 4.8 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling RNA_helicase PF00910.22 KHN69315.1 - 0.013 15.9 0.8 0.17 12.3 0.1 3.2 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KHN69315.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 KHN69315.1 - 0.019 14.5 0.1 0.052 13.1 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 KHN69315.1 - 0.023 13.8 0.0 0.056 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KHN69315.1 - 0.052 13.8 0.0 0.18 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KHN69315.1 - 0.052 13.6 0.2 0.052 13.6 0.2 3.4 4 0 0 4 4 4 0 AAA domain DUF1129 PF06570.11 KHN69315.1 - 0.059 12.9 9.3 0.17 11.3 9.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DC_STAMP PF07782.13 KHN69315.1 - 0.097 12.5 0.7 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Zeta_toxin PF06414.12 KHN69315.1 - 0.11 11.8 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF1040 PF06288.13 KHN69315.1 - 0.25 11.8 1.9 6.5 7.2 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1040) ATP_bind_1 PF03029.17 KHN69316.1 - 1.8e-60 204.7 0.8 2.1e-60 204.5 0.8 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KHN69316.1 - 2.9e-06 27.2 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 KHN69316.1 - 0.00012 22.7 0.0 0.00034 21.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KHN69316.1 - 0.00088 19.0 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN69316.1 - 0.0017 18.6 0.0 0.0049 17.1 0.0 1.9 1 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KHN69316.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KHN69316.1 - 0.012 16.0 0.1 0.062 13.7 0.0 2.2 2 1 1 3 3 3 0 RNA helicase NB-ARC PF00931.22 KHN69316.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KHN69316.1 - 0.032 14.4 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KHN69316.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KHN69316.1 - 0.063 13.2 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Cytidylate_kin PF02224.18 KHN69316.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase PduV-EutP PF10662.9 KHN69316.1 - 0.091 12.5 0.0 0.82 9.4 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 KHN69316.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KHN69316.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane PF01061.24 KHN69318.1 - 1.4e-36 125.9 23.6 2.3e-36 125.2 23.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KHN69318.1 - 3.9e-18 66.3 0.0 6.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KHN69318.1 - 7.3e-09 35.2 18.0 1.1e-08 34.6 18.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 KHN69318.1 - 4.9e-06 26.1 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KHN69318.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KHN69318.1 - 0.00069 19.5 0.3 0.74 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KHN69318.1 - 0.0036 17.0 0.1 0.008 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KHN69318.1 - 0.004 17.2 0.2 0.011 15.8 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KHN69318.1 - 0.0054 17.0 0.5 0.026 14.8 0.5 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KHN69318.1 - 0.0062 16.3 0.2 2.3 7.9 0.1 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 KHN69318.1 - 0.011 15.4 0.4 0.033 13.9 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KHN69318.1 - 0.015 15.9 0.2 0.026 15.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KHN69318.1 - 0.022 15.2 1.3 0.22 12.0 1.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KHN69318.1 - 0.026 14.1 0.3 0.052 13.1 0.3 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KHN69318.1 - 0.044 14.2 0.1 0.091 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KHN69318.1 - 0.063 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 KHN69318.1 - 0.088 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KHN69318.1 - 0.13 12.6 1.0 0.53 10.6 1.0 1.9 1 1 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KHN69318.1 - 0.16 11.2 10.3 0.4 9.9 10.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein MukB PF04310.12 KHN69319.1 - 0.14 12.0 0.7 0.24 11.2 0.7 1.3 1 0 0 1 1 1 0 MukB N-terminal PCI PF01399.27 KHN69321.1 - 9.3e-14 51.8 0.9 3.3e-13 50.0 0.9 2.0 1 0 0 1 1 1 1 PCI domain RPN6_N PF18055.1 KHN69321.1 - 5.4e-09 36.4 1.5 1.2e-08 35.3 0.4 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4363 PF14276.6 KHN69321.1 - 0.087 12.9 0.4 23 5.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Fer2 PF00111.27 KHN69322.1 - 4.6e-09 36.1 0.1 6.2e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 KHN69322.1 - 0.053 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Magnetochrome domain AAA_23 PF13476.6 KHN69323.1 - 3.2e-17 63.7 29.3 3.2e-17 63.7 29.3 5.9 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 KHN69323.1 - 3.7e-10 39.6 10.9 1.1e-05 25.0 0.0 2.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KHN69323.1 - 5.7e-09 36.2 0.2 0.00033 20.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KHN69323.1 - 1.9e-05 24.6 45.5 0.0013 18.5 4.6 4.8 2 2 1 4 4 4 3 AAA ATPase domain ABC_tran PF00005.27 KHN69323.1 - 0.00043 20.8 8.6 0.1 13.1 0.0 4.5 3 2 1 4 4 4 2 ABC transporter AAA_29 PF13555.6 KHN69323.1 - 0.0054 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KHN69323.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KHN69323.1 - 0.013 15.8 0.0 0.056 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain Mis12 PF05859.12 KHN69324.1 - 7.1e-05 22.9 4.1 0.04 14.0 4.1 2.6 1 1 0 1 1 1 1 Mis12 protein PVL_ORF50 PF07768.11 KHN69324.1 - 0.53 10.6 3.0 0.59 10.5 1.3 1.9 1 1 1 2 2 2 0 PVL ORF-50-like family Actin_micro PF17003.5 KHN69325.1 - 1.6e-99 333.6 9.1 2.1e-98 329.9 9.1 1.9 1 1 0 1 1 1 1 Putative actin-like family CDC37_N PF03234.14 KHN69326.1 - 7.7e-09 36.5 7.0 7.7e-09 36.5 7.0 1.8 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding Lin-8 PF03353.15 KHN69326.1 - 0.061 12.9 4.9 0.47 10.0 1.1 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RPAP1_N PF08621.10 KHN69326.1 - 0.083 12.7 7.3 0.56 10.0 0.3 2.7 2 0 0 2 2 2 0 RPAP1-like, N-terminal Vpu PF00558.19 KHN69326.1 - 0.82 9.5 5.2 1 9.2 3.2 2.2 2 0 0 2 2 2 0 Vpu protein AAA_23 PF13476.6 KHN69326.1 - 0.88 10.0 8.9 1.6 9.2 8.9 1.5 1 1 0 1 1 1 0 AAA domain TMEM208_SND2 PF05620.11 KHN69327.1 - 4.3e-15 55.9 0.9 4.7e-15 55.8 0.9 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Rad60-SLD PF11976.8 KHN69328.1 - 4.6e-09 36.0 0.0 5.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KHN69328.1 - 0.0061 16.3 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Paf1 PF03985.13 KHN69329.1 - 0.00057 19.0 4.4 0.0081 15.2 0.6 2.0 1 1 0 2 2 2 2 Paf1 SMC_N PF02463.19 KHN69330.1 - 6e-58 195.9 32.5 1.1e-56 191.7 32.5 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KHN69330.1 - 1.2e-18 67.5 0.0 3.2e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KHN69330.1 - 2.8e-17 63.9 0.1 2.8e-17 63.9 0.1 6.0 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 KHN69330.1 - 7.3e-15 55.6 0.2 2.8e-07 30.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KHN69330.1 - 9.8e-10 38.7 43.8 8.7e-09 35.5 22.8 4.2 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KHN69330.1 - 1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MbeD_MobD PF04899.12 KHN69330.1 - 0.021 14.9 0.5 0.55 10.4 0.2 3.1 2 0 0 2 2 2 0 MbeD/MobD like DUF3618 PF12277.8 KHN69330.1 - 0.055 13.7 3.0 0.34 11.2 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) ABC_tran PF00005.27 KHN69330.1 - 0.34 11.4 0.1 0.34 11.4 0.1 6.0 4 2 0 4 4 4 0 ABC transporter LURAP PF14854.6 KHN69330.1 - 7 6.6 11.9 0.072 13.0 0.7 3.5 3 1 0 3 3 3 0 Leucine rich adaptor protein 2OG-FeII_Oxy_4 PF13661.6 KHN69331.1 - 3.8e-13 49.9 0.1 1.1e-12 48.4 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KHN69331.1 - 2.5e-12 47.5 0.1 7.2e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4178 PF13785.6 KHN69331.1 - 0.088 12.9 0.1 2.9 8.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4178) Sec62 PF03839.16 KHN69332.1 - 2.9e-31 108.7 1.3 2.9e-31 108.7 1.3 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 KHN69332.1 - 0.006 16.6 0.1 0.0096 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2207 PF09972.9 KHN69332.1 - 0.04 12.7 0.5 0.048 12.4 0.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 KHN69332.1 - 0.75 8.0 5.0 0.98 7.6 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Corona_M PF01635.18 KHN69332.1 - 0.8 9.0 5.0 1.1 8.5 5.0 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein PUB PF09409.10 KHN69334.1 - 0.045 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 PUB domain Med18 PF09637.10 KHN69334.1 - 0.1 12.4 0.1 0.43 10.4 0.1 1.8 1 1 0 1 1 1 0 Med18 protein DUF3087 PF11286.8 KHN69335.1 - 0.19 11.2 6.1 0.51 9.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) MIP PF00230.20 KHN69336.1 - 1.2e-24 87.3 12.9 6.3e-24 84.9 12.9 1.8 1 1 0 1 1 1 1 Major intrinsic protein ECH_1 PF00378.20 KHN69336.1 - 0.12 11.7 0.3 0.16 11.3 0.3 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF1072 PF06380.11 KHN69336.1 - 1.3 8.9 5.8 1.2 9.0 0.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1072) CAF1C_H4-bd PF12265.8 KHN69337.1 - 3.5e-26 91.3 2.1 4.1e-25 87.8 0.1 2.9 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KHN69337.1 - 1.2e-23 83.0 15.2 1.3e-05 25.8 0.3 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69337.1 - 2.7e-05 24.4 0.3 0.012 15.9 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KHN69337.1 - 0.00083 18.4 0.1 2.1 7.2 0.2 3.4 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DnaJ_C PF01556.18 KHN69338.1 - 3e-27 95.5 0.7 4.2e-27 95.1 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KHN69338.1 - 2.2e-09 37.5 17.3 5.3e-09 36.3 17.3 1.7 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KHN69338.1 - 4.4e-07 29.9 0.8 1.5e-06 28.2 0.8 1.9 1 1 0 1 1 1 1 DnaJ domain Anti-TRAP PF15777.5 KHN69338.1 - 0.17 11.9 12.5 0.53 10.3 2.6 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KHN69338.1 - 1.4 8.6 7.4 0.35 10.5 2.5 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 KHN69338.1 - 4.6 7.3 8.9 25 4.9 3.0 2.5 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 KHN69338.1 - 6.2 6.9 13.8 1.1e+02 3.0 13.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon NPL4 PF05021.15 KHN69339.1 - 1.1e-44 153.0 0.0 1.7e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KHN69339.1 - 1.5e-27 96.5 6.1 1.1e-26 93.7 6.1 2.1 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 KHN69339.1 - 7.7e-05 21.9 2.7 7.7e-05 21.9 2.7 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Sec3_C PF09763.9 KHN69340.1 - 4.9e-17 61.6 13.7 5e-17 61.6 12.2 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec3 SUKH_5 PF14567.6 KHN69340.1 - 0.011 15.5 5.1 0.072 12.8 0.0 3.1 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall DUF5309 PF17236.2 KHN69340.1 - 0.051 12.9 0.4 0.11 11.8 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5309) LsmAD PF06741.13 KHN69340.1 - 0.19 12.3 3.7 0.19 12.3 1.4 2.3 2 0 0 2 2 2 0 LsmAD domain Nnf1 PF03980.14 KHN69340.1 - 0.42 11.0 5.3 15 6.1 0.2 3.3 3 0 0 3 3 3 0 Nnf1 DUF3781 PF12636.7 KHN69340.1 - 0.6 10.0 4.0 0.44 10.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) GrpE PF01025.19 KHN69340.1 - 5.8 6.5 12.3 27 4.4 7.3 3.0 2 1 0 2 2 2 0 GrpE Pkinase PF00069.25 KHN69341.1 - 4.3e-58 196.8 0.0 5.4e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69341.1 - 3.8e-35 121.4 0.0 5.4e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69341.1 - 8.8e-05 21.9 0.0 0.0027 17.1 0.0 2.7 1 1 2 3 3 3 1 Kinase-like FTA2 PF13095.6 KHN69341.1 - 0.0072 16.0 0.2 0.14 11.7 0.1 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KHN69341.1 - 0.012 14.6 0.1 0.015 14.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KHN69341.1 - 0.015 15.2 0.2 0.095 12.6 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DNA_RNApol_7kD PF03604.13 KHN69341.1 - 0.5 10.1 7.5 0.37 10.5 3.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.22 KHN69341.1 - 0.75 9.7 17.1 1.1 9.2 15.2 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac-A_C PF08646.10 KHN69341.1 - 3.8 7.2 8.6 7.1 6.4 8.6 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain Gp_dh_C PF02800.20 KHN69342.1 - 5.4e-54 182.1 0.0 7.3e-54 181.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KHN69342.1 - 2.4e-25 88.8 0.0 4.9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KHN69342.1 - 0.00024 20.5 0.1 0.00067 19.1 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YesK PF14150.6 KHN69343.1 - 0.024 14.8 2.2 0.051 13.8 1.5 1.9 1 1 0 1 1 1 0 YesK-like protein RL10P_insert PF17777.1 KHN69344.1 - 5.1e-20 71.3 0.0 9.4e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KHN69344.1 - 1.6e-19 69.9 2.0 2.9e-19 69.1 2.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DEAD PF00270.29 KHN69345.1 - 5.2e-26 91.5 0.1 4e-25 88.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sec63 PF02889.16 KHN69345.1 - 3e-22 79.0 5.2 7.8e-22 77.7 5.2 1.6 1 1 0 1 1 1 1 Sec63 Brl domain ResIII PF04851.15 KHN69345.1 - 4e-11 43.2 0.0 1.2e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KHN69345.1 - 2.1e-07 31.3 0.0 8.5e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KHN69345.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_pol_Rpb8 PF03870.15 KHN69346.1 - 2.1e-17 63.6 0.0 9.4e-08 32.3 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KHN69346.1 - 0.00015 21.8 0.1 0.00019 21.4 0.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Cullin PF00888.22 KHN69347.1 - 7.2e-42 143.8 14.2 8.4e-26 90.7 0.1 2.2 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 KHN69347.1 - 5.4e-05 23.2 2.3 0.00014 21.8 0.1 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain HTH_9 PF08221.11 KHN69347.1 - 0.02 15.0 0.2 0.092 12.9 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Pam16 PF03656.13 KHN69348.1 - 8.2e-07 29.1 0.0 8.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 KHN69348.1 - 0.0049 17.0 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF5410 PF17422.2 KHN69348.1 - 0.059 12.6 0.0 0.066 12.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5410) Nop52 PF05997.12 KHN69349.1 - 0.0056 16.5 6.0 0.0061 16.4 4.6 1.7 1 1 0 1 1 1 1 Nucleolar protein,Nop52 Rsbr_N PF08678.10 KHN69349.1 - 0.053 13.6 0.4 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Rsbr N terminal DUF4116 PF13475.6 KHN69349.1 - 0.16 11.8 1.9 6.9 6.5 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) Tfb4 PF03850.14 KHN69350.1 - 5.6e-21 75.2 14.1 7.1e-17 61.8 11.8 2.9 1 1 1 2 2 2 2 Transcription factor Tfb4 HisK_N PF09385.10 KHN69350.1 - 0.079 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase N terminal NIF PF03031.18 KHN69351.1 - 7.5e-28 97.3 0.3 3.8e-27 95.0 0.2 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT_2 PF16589.5 KHN69351.1 - 1.1e-05 25.7 0.0 3.1e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KHN69351.1 - 0.0031 17.8 0.1 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Acid_PPase PF12689.7 KHN69351.1 - 0.13 12.0 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Acid Phosphatase Abhydrolase_1 PF00561.20 KHN69352.1 - 3e-10 40.2 0.2 4.6e-08 33.0 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KHN69352.1 - 1.7e-08 34.1 0.0 2.7e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KHN69352.1 - 0.0049 17.5 0.0 0.0098 16.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family MeaB PF03308.16 KHN69352.1 - 0.027 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 KHN69353.1 - 5.2e-06 26.1 2.0 0.0053 16.2 0.4 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 DHC_N2 PF08393.13 KHN69353.1 - 0.037 13.1 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 Ribosomal_L24e PF01246.20 KHN69355.1 - 1.7e-11 44.2 0.0 2.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3509 PF12021.8 KHN69355.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Rep_fac-A_3 PF08661.11 KHN69356.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Replication factor A protein 3 RNA_pol_Rpb5_C PF01191.19 KHN69357.1 - 3.6e-28 97.2 0.0 6.3e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KHN69357.1 - 1.3e-05 25.7 0.1 2.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain HTH_26 PF13443.6 KHN69358.1 - 0.13 12.7 0.1 7.1 7.2 0.1 2.3 1 1 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DUF3347 PF11827.8 KHN69359.1 - 0.022 15.0 1.3 0.022 14.9 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) GIT1_C PF12205.8 KHN69359.1 - 0.036 14.2 1.5 0.048 13.8 1.5 1.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term BUD22 PF09073.10 KHN69359.1 - 0.064 12.6 0.6 0.066 12.5 0.6 1.0 1 0 0 1 1 1 0 BUD22 DUF3201 PF11447.8 KHN69359.1 - 0.082 12.4 0.3 0.093 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) CtIP_N PF10482.9 KHN69359.1 - 0.18 11.9 3.7 2.7 8.1 1.1 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Diphthamide_syn PF01866.17 KHN69360.1 - 7.5e-94 314.6 0.0 9.7e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein EnY2 PF10163.9 KHN69361.1 - 7.9e-05 22.9 0.0 9.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 PP2C_C PF07830.13 KHN69361.1 - 0.028 14.9 0.0 0.032 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain T2SSK PF03934.13 KHN69362.1 - 0.018 14.5 0.2 0.031 13.7 0.0 1.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K CDtoxinA PF03498.14 KHN69363.1 - 0.0011 18.6 0.2 0.086 12.4 0.0 2.3 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain Ricin_B_lectin PF00652.22 KHN69363.1 - 0.014 15.6 0.1 0.037 14.3 0.0 1.8 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Ribosomal_L37ae PF01780.19 KHN69364.1 - 1.1e-30 105.5 7.4 1.2e-30 105.4 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 KHN69364.1 - 0.0022 18.3 2.2 1.8 9.2 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 KHN69364.1 - 0.0056 16.6 2.1 0.0087 16.0 2.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain VATC PF18716.1 KHN69364.1 - 0.0092 15.8 1.1 0.47 10.4 0.1 2.2 2 0 0 2 2 2 1 Vms1-associating treble clef domain HypA PF01155.19 KHN69364.1 - 0.013 15.5 0.4 0.016 15.2 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_1 PF00130.22 KHN69364.1 - 0.019 14.8 2.8 0.03 14.2 2.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sgf11 PF08209.11 KHN69364.1 - 0.035 13.7 1.3 0.86 9.2 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) NOB1_Zn_bind PF08772.11 KHN69364.1 - 0.037 14.2 2.8 0.053 13.7 2.8 1.6 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-BED PF02892.15 KHN69364.1 - 0.044 13.8 5.1 1 9.5 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 KHN69364.1 - 0.081 13.1 0.6 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 KHN69364.1 - 0.12 12.4 1.7 3.7 7.7 0.3 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger C1_2 PF03107.16 KHN69364.1 - 0.15 12.4 4.2 1.5 9.2 4.1 2.0 1 1 0 1 1 1 0 C1 domain Rtt106 PF08512.12 KHN69365.1 - 7.7e-16 58.3 0.3 5.8e-14 52.3 0.0 3.0 3 0 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 KHN69365.1 - 5.1e-06 26.8 0.4 0.00045 20.6 0.0 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain ANAPC4_WD40 PF12894.7 KHN69366.1 - 1.7e-06 28.2 0.3 0.3 11.4 0.1 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KHN69366.1 - 7.9e-06 26.5 6.4 0.52 11.3 0.0 5.0 4 1 1 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 KHN69366.1 - 0.0016 17.2 1.7 0.12 10.9 0.1 3.0 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KHN69366.1 - 0.012 14.6 0.1 0.53 9.2 0.0 2.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome PF00227.26 KHN69368.1 - 1.5e-22 80.0 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KHN69368.1 - 9.9e-10 37.9 0.2 1.9e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NAD_kinase PF01513.21 KHN69369.1 - 3.9e-18 65.7 0.9 1.1e-17 64.2 0.9 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KHN69369.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DEAD PF00270.29 KHN69370.1 - 2.6e-21 76.2 0.4 5.3e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69370.1 - 1.3e-14 54.5 0.0 4.3e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69370.1 - 0.0036 17.3 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KHN69370.1 - 0.013 15.4 0.1 0.36 10.8 0.0 2.2 1 1 0 2 2 2 0 Flavivirus DEAD domain bPH_1 PF08000.11 KHN69370.1 - 0.037 14.1 1.7 0.098 12.7 0.1 2.3 3 0 0 3 3 3 0 Bacterial PH domain AAA_22 PF13401.6 KHN69370.1 - 0.083 13.2 0.1 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain 7TM_GPCR_Srt PF10321.9 KHN69371.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt Helicase_C PF00271.31 KHN69374.1 - 9.1e-22 77.5 0.0 4.9e-19 68.7 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KHN69374.1 - 8.5e-21 74.5 0.0 7e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KHN69374.1 - 2.6e-17 63.3 5.3 2.6e-17 63.3 5.3 2.2 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 KHN69374.1 - 2.9e-13 49.6 0.8 6.4e-13 48.5 0.8 1.6 1 0 0 1 1 1 1 RQC domain MarR_2 PF12802.7 KHN69374.1 - 0.011 15.6 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 MarR family ResIII PF04851.15 KHN69374.1 - 0.071 13.1 0.0 0.51 10.3 0.0 2.4 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit HTH_36 PF13730.6 KHN69374.1 - 0.074 13.0 0.0 0.5 10.4 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF272 PF03312.15 KHN69374.1 - 0.079 13.2 1.5 0.12 12.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF272) HTH_24 PF13412.6 KHN69374.1 - 0.18 11.4 1.4 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3449 PF11931.8 KHN69375.1 - 3.3e-25 89.0 4.1 3.3e-25 89.0 4.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KHN69375.1 - 0.068 13.7 2.4 0.12 12.9 1.0 2.3 2 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_2 PF12756.7 KHN69375.1 - 4.5 7.7 13.6 5 7.5 1.4 3.4 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KHN69375.1 - 5.7 7.5 6.9 28 5.3 1.9 3.9 3 1 1 4 4 4 0 Zinc-finger of C2H2 type Dus PF01207.17 KHN69378.1 - 4.7e-44 150.7 0.0 9.4e-44 149.8 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NepR PF18557.1 KHN69379.1 - 0.0055 16.3 0.2 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 Anti-sigma factor NepR hGDE_central PF14702.6 KHN69379.1 - 0.013 15.2 0.2 0.015 14.9 0.2 1.1 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Tubulin PF00091.25 KHN69380.1 - 5.7e-67 225.7 0.0 1.3e-66 224.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KHN69380.1 - 4.4e-49 165.8 0.2 6.7e-49 165.2 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KHN69380.1 - 0.0001 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain RPN7 PF10602.9 KHN69381.1 - 0.15 11.7 2.7 0.56 9.9 0.3 2.0 1 1 1 2 2 2 0 26S proteasome subunit RPN7 DUF3551 PF12071.8 KHN69381.1 - 0.2 11.7 1.7 10 6.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3551) FH2 PF02181.23 KHN69383.1 - 9.7e-33 113.8 1.5 9.7e-33 113.8 1.5 1.9 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KHN69383.1 - 0.00019 21.1 0.7 0.00064 19.3 0.7 1.8 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain GlutR_N PF05201.15 KHN69383.1 - 0.074 12.8 0.1 8.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, N-terminal domain EF-hand_7 PF13499.6 KHN69384.1 - 0.37 11.3 4.5 1 9.9 4.5 1.8 1 1 0 1 1 1 0 EF-hand domain pair DUF2627 PF11118.8 KHN69386.1 - 0.22 12.1 6.0 1.1 9.9 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) YwiC PF14256.6 KHN69386.1 - 1.1 9.6 7.7 3.1 8.1 7.7 1.8 1 1 0 1 1 1 0 YwiC-like protein DUF4337 PF14235.6 KHN69386.1 - 5.2 7.2 5.6 2.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) GDA1_CD39 PF01150.17 KHN69387.1 - 1.1e-20 73.7 2.0 1.8e-20 73.0 0.2 2.0 1 1 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KHN69387.1 - 5.7e-06 26.0 0.0 7.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family FtsA PF14450.6 KHN69387.1 - 0.011 16.1 1.4 0.061 13.8 0.7 2.3 2 1 0 2 2 2 0 Cell division protein FtsA HTH_ParB PF17762.1 KHN69387.1 - 0.13 12.1 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 HTH domain found in ParB protein Pkinase PF00069.25 KHN69388.1 - 1.7e-54 185.0 0.0 1.9e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69388.1 - 2e-26 92.8 0.0 2.8e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69388.1 - 0.0055 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KHN69388.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4160 PF13711.6 KHN69388.1 - 0.041 14.2 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Kdo PF06293.14 KHN69388.1 - 0.095 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KHN69388.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KHN69388.1 - 0.13 11.0 0.1 0.23 10.2 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase SIS PF01380.22 KHN69389.1 - 2.5e-52 176.1 0.4 3.9e-30 104.4 0.2 2.7 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KHN69389.1 - 3.3e-17 62.9 0.0 8.5e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KHN69389.1 - 4.4e-13 49.2 0.0 1.1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KHN69389.1 - 4.9e-05 22.4 0.0 8.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Phage_tail_2 PF06199.11 KHN69391.1 - 0.045 13.8 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Phage tail tube protein CBM_21 PF03370.13 KHN69391.1 - 0.048 13.8 0.4 0.089 13.0 0.4 1.5 1 0 0 1 1 1 0 Carbohydrate/starch-binding module (family 21) ArenaCapSnatch PF17296.2 KHN69391.1 - 0.079 12.4 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Arenavirus cap snatching domain FAM72 PF14976.6 KHN69392.1 - 1.3e-20 74.1 10.7 1.6e-20 73.8 10.7 1.1 1 0 0 1 1 1 1 FAM72 protein DUF155 PF02582.14 KHN69393.1 - 2e-49 168.0 0.2 2.8e-49 167.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0193 PF05250.11 KHN69393.1 - 0.014 15.2 0.3 0.023 14.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) BLI1 PF17324.2 KHN69393.1 - 0.03 15.0 0.6 0.03 15.0 0.6 1.8 2 0 0 2 2 2 0 BLOC-1 interactor 1 Orf78 PF06024.12 KHN69393.1 - 0.044 14.1 1.3 0.095 13.0 1.3 1.5 1 0 0 1 1 1 0 Orf78 (ac78) CD34_antigen PF06365.12 KHN69393.1 - 0.054 13.1 0.5 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 CD34/Podocalyxin family eIF-5_eIF-2B PF01873.17 KHN69394.1 - 2.4e-32 111.2 0.5 1.3e-30 105.7 0.1 2.2 2 0 0 2 2 2 2 Domain found in IF2B/IF5 FtsJ PF01728.19 KHN69395.1 - 8.5e-50 169.3 0.0 1.8e-49 168.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KHN69395.1 - 6.5e-21 74.8 13.4 6.5e-21 74.8 13.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 KHN69395.1 - 0.0056 16.3 0.0 0.019 14.6 0.0 1.9 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FlxA PF14282.6 KHN69395.1 - 8.8 6.4 8.4 2 8.5 4.3 2.0 2 0 0 2 2 2 0 FlxA-like protein ATP-synt_C PF00137.21 KHN69396.1 - 5.1e-11 42.8 18.0 1.8e-07 31.4 6.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C RRM_1 PF00076.22 KHN69398.1 - 0.00024 20.9 1.2 0.009 15.8 0.2 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AsnC_trans_reg PF01037.21 KHN69398.1 - 0.0022 17.9 0.8 0.02 14.8 0.2 2.4 2 0 0 2 2 2 1 Lrp/AsnC ligand binding domain FtsX_ECD PF18075.1 KHN69398.1 - 0.012 16.2 1.6 2 9.1 0.0 2.7 3 1 0 3 3 3 0 FtsX extracellular domain DUF4523 PF15023.6 KHN69398.1 - 0.085 12.7 0.2 0.3 10.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) Ribosomal_L40e PF01020.17 KHN69399.1 - 5.3e-06 26.2 12.3 1e-05 25.3 12.3 1.5 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 KHN69399.1 - 1.6e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KHN69399.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L22 PF00237.19 KHN69400.1 - 1.2e-35 121.9 0.2 2e-35 121.1 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Proteasome PF00227.26 KHN69401.1 - 2.6e-26 92.3 0.0 3.7e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L20 PF00453.18 KHN69402.1 - 0.053 13.6 1.4 0.12 12.4 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L20 BLYB PF05289.11 KHN69402.1 - 0.18 12.0 3.0 0.39 10.9 0.4 2.7 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein YTV PF07639.11 KHN69402.1 - 0.31 11.1 1.7 26 5.0 0.1 3.4 3 0 0 3 3 3 0 YTV ApoLp-III PF07464.11 KHN69402.1 - 0.95 9.5 10.5 0.98 9.5 6.5 2.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SpoIISA_toxin PF14171.6 KHN69402.1 - 5.2 6.7 6.1 0.96 9.1 0.2 2.4 3 0 0 3 3 3 0 Toxin SpoIISA, type II toxin-antitoxin system Dopey_N PF04118.14 KHN69403.1 - 5.3e-64 216.2 1.8 5.3e-64 216.2 1.8 3.9 3 1 0 3 3 3 1 Dopey, N-terminal EAP30 PF04157.16 KHN69403.1 - 0.011 15.0 0.1 2.6 7.3 0.0 2.8 3 0 0 3 3 3 0 EAP30/Vps36 family Ribosomal_L37e PF01907.19 KHN69405.1 - 2.6e-17 62.7 8.0 2.6e-17 62.7 8.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 KHN69405.1 - 0.032 14.3 2.9 0.048 13.7 2.9 1.2 1 0 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.8 KHN69405.1 - 0.33 10.9 3.1 0.58 10.1 3.1 1.3 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF812 PF05667.11 KHN69408.1 - 0.00047 19.2 3.4 0.00056 18.9 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Dynactin PF12455.8 KHN69408.1 - 0.00055 19.3 1.9 0.0013 18.1 1.9 1.6 1 1 0 1 1 1 1 Dynein associated protein ADIP PF11559.8 KHN69408.1 - 0.007 16.5 9.0 0.011 15.8 9.0 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 KHN69408.1 - 0.016 15.2 2.3 0.032 14.3 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KHN69408.1 - 0.02 14.9 6.5 0.033 14.2 6.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRRFIP PF09738.9 KHN69408.1 - 0.026 14.0 7.6 0.046 13.2 7.6 1.4 1 0 0 1 1 1 0 LRRFIP family DUF489 PF04356.12 KHN69408.1 - 0.034 14.2 1.1 0.044 13.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF3450 PF11932.8 KHN69408.1 - 0.035 13.4 4.9 0.057 12.7 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Peptidase_M28 PF04389.17 KHN69408.1 - 0.051 13.3 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Peptidase family M28 DUF4200 PF13863.6 KHN69408.1 - 0.13 12.6 9.5 0.19 12.1 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_tail_APC PF16778.5 KHN69408.1 - 0.16 11.8 1.6 1.2 9.1 0.3 2.3 1 1 1 2 2 2 0 Phage tail assembly chaperone protein TMF_DNA_bd PF12329.8 KHN69408.1 - 0.19 11.7 8.6 0.26 11.3 7.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec20 PF03908.13 KHN69408.1 - 0.27 11.2 3.7 0.82 9.6 0.5 2.2 2 0 0 2 2 2 0 Sec20 ZapB PF06005.12 KHN69408.1 - 0.42 11.1 10.1 1 9.8 10.1 1.8 1 1 0 1 1 1 0 Cell division protein ZapB LMBR1 PF04791.16 KHN69408.1 - 0.46 9.3 2.6 0.56 9.0 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 KHN69408.1 - 0.66 10.6 9.2 0.78 10.4 7.3 1.9 2 1 1 3 3 2 0 Initiation control protein YabA Atg14 PF10186.9 KHN69408.1 - 0.71 8.9 10.3 0.79 8.8 10.0 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-Q PF13094.6 KHN69408.1 - 0.78 9.9 11.7 0.25 11.5 8.2 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TolA_bind_tri PF16331.5 KHN69408.1 - 0.91 9.6 12.2 0.46 10.6 4.6 2.4 2 1 1 3 3 3 0 TolA binding protein trimerisation Latarcin PF10279.9 KHN69408.1 - 1 9.8 8.5 0.73 10.3 4.3 2.1 1 1 1 2 2 2 0 Latarcin precursor DUF724 PF05266.14 KHN69408.1 - 1.4 8.7 7.3 4.6 7.0 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Bap31_Bap29_C PF18035.1 KHN69408.1 - 1.6 8.8 4.7 0.39 10.7 1.3 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ACCA PF03255.14 KHN69408.1 - 1.8 8.4 5.6 1.5 8.6 2.8 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FapA PF03961.13 KHN69408.1 - 3 6.3 8.6 4.1 5.9 7.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A E1-E2_ATPase PF00122.20 KHN69409.1 - 1.9e-19 69.9 12.0 2.9e-19 69.3 0.6 4.1 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KHN69409.1 - 2.6e-14 54.0 0.6 0.00042 20.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 KHN69409.1 - 5.9e-07 29.6 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 KHN69409.1 - 6.5e-05 22.9 0.1 0.00017 21.6 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Y_phosphatase PF00102.27 KHN69409.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hydrolase_3 PF08282.12 KHN69409.1 - 0.048 13.4 0.2 0.49 10.1 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4149 PF13664.6 KHN69409.1 - 3 8.2 5.3 1.4 9.3 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Gastrin PF00918.17 KHN69413.1 - 0.0046 17.9 0.6 0.0084 17.1 0.6 1.5 1 0 0 1 1 1 1 Gastrin/cholecystokinin family tRNA-synt_2b PF00587.25 KHN69414.1 - 1.1e-38 133.0 0.0 7.5e-38 130.3 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 KHN69414.1 - 4.8e-11 42.6 0.0 1.4e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HGTP_anticodon PF03129.20 KHN69414.1 - 1.1e-09 38.3 0.3 3.5e-09 36.7 0.3 1.9 1 0 0 1 1 1 1 Anticodon binding domain Njmu-R1 PF15053.6 KHN69414.1 - 0.072 12.2 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family Telomere_reg-2 PF10193.9 KHN69415.1 - 0.033 14.6 0.1 0.076 13.5 0.1 1.7 1 0 0 1 1 1 0 Telomere length regulation protein Aida_N PF08910.10 KHN69416.1 - 5.2 7.5 5.8 11 6.5 1.4 3.4 3 0 0 3 3 3 0 Aida N-terminus Lectin_leg-like PF03388.13 KHN69417.1 - 0.0018 17.6 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family HetR_C PF18460.1 KHN69417.1 - 0.0071 16.2 0.1 0.066 13.1 0.0 2.3 1 1 1 2 2 2 1 Heterocyst differentiation regulator C-terminal Hood domain Spc7 PF08317.11 KHN69417.1 - 0.028 13.3 2.4 0.037 12.9 0.7 1.7 1 1 0 2 2 2 0 Spc7 kinetochore protein Sir1 PF11603.8 KHN69417.1 - 0.054 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Regulatory protein Sir1 DUF1664 PF07889.12 KHN69417.1 - 0.082 12.9 1.8 0.15 12.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5337 PF17272.2 KHN69417.1 - 0.15 11.9 0.2 0.27 11.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5337) CdvA PF18822.1 KHN69417.1 - 0.22 11.3 4.3 0.87 9.4 1.6 2.4 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Dus PF01207.17 KHN69418.1 - 4.5e-69 232.9 0.1 6.1e-69 232.5 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KHN69418.1 - 0.0034 16.9 0.0 0.0082 15.6 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.21 KHN69418.1 - 0.0065 15.7 0.0 0.29 10.3 0.0 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.14 KHN69418.1 - 0.042 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG V-SNARE_C PF12352.8 KHN69419.1 - 0.00012 22.3 1.4 0.00032 20.9 1.2 1.9 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KHN69419.1 - 0.033 14.1 1.0 0.076 12.9 0.2 2.1 2 2 0 2 2 2 0 Sec20 DCP2 PF05026.13 KHN69420.1 - 4.4e-14 52.6 1.9 6.5e-14 52.0 0.6 2.0 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 KHN69420.1 - 2.2e-11 43.9 0.0 3.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.29 KHN69421.1 - 2.5e-40 138.0 0.0 5.8e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN69421.1 - 4.4e-12 45.6 0.1 9.2e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KHN69421.1 - 4.6e-08 32.9 0.1 9.8e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KHN69421.1 - 2.2e-05 24.7 0.0 6.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KHN69421.1 - 2.7e-05 24.5 0.4 0.025 14.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KHN69421.1 - 3.4e-05 23.1 0.0 6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KHN69421.1 - 0.00027 20.9 0.7 0.0015 18.6 0.2 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KHN69421.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KHN69421.1 - 0.002 18.6 0.2 0.013 15.9 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KHN69421.1 - 0.0059 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KHN69421.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KHN69421.1 - 0.017 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 KHN69421.1 - 0.019 14.2 0.0 0.79 8.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 KHN69421.1 - 0.026 14.8 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KHN69421.1 - 0.026 14.2 0.2 0.077 12.7 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 KHN69421.1 - 0.034 14.7 0.0 0.067 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KHN69421.1 - 0.054 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KHN69421.1 - 0.19 11.3 0.4 1.5 8.3 0.2 2.3 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KHN69421.1 - 0.2 11.3 0.6 0.54 9.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain UPF0086 PF01868.16 KHN69422.1 - 2.4e-05 24.2 0.8 6.9e-05 22.7 0.8 1.8 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Shugoshin_N PF07558.11 KHN69423.1 - 0.0059 16.4 3.1 0.013 15.4 3.1 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region tRNA-synt_2d PF01409.20 KHN69424.1 - 2.7e-91 305.4 0.0 3.6e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KHN69424.1 - 4.7e-12 46.0 0.0 1.8e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KHN69424.1 - 4.8e-08 32.7 0.0 4.5e-07 29.5 0.0 2.2 2 1 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KHN69424.1 - 0.0038 16.4 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Acetyltransf_10 PF13673.7 KHN69426.1 - 8.6e-06 25.7 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KHN69426.1 - 0.0003 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 KHN69426.1 - 0.00048 20.3 0.0 0.00067 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KHN69426.1 - 0.0024 18.3 0.1 0.0041 17.5 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KHN69426.1 - 0.0033 17.6 0.1 0.004 17.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SH2_2 PF14633.6 KHN69427.1 - 4.9e-17 62.1 1.2 1.7e-16 60.3 1.2 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 KHN69427.1 - 0.023 15.6 0.0 0.1 13.5 0.0 2.2 1 0 0 1 1 1 0 HHH domain Ribosomal_S5 PF00333.20 KHN69428.1 - 8.4e-24 83.3 2.8 1.6e-23 82.5 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KHN69428.1 - 6.2e-20 70.4 0.0 1.1e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain VPS9 PF02204.18 KHN69429.1 - 2.8e-22 78.9 0.3 6.1e-22 77.8 0.3 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RRM_1 PF00076.22 KHN69430.1 - 8.6e-15 54.3 0.1 2.7e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KHN69430.1 - 0.002 18.1 0.0 0.0046 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding domain Ig_6 PF18452.1 KHN69430.1 - 0.06 12.9 0.2 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain RRM_7 PF16367.5 KHN69430.1 - 0.1 12.8 0.6 1.2 9.2 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif KIX_2 PF16987.5 KHN69431.1 - 1.3e-07 31.5 1.7 2e-07 30.9 0.3 2.1 2 0 0 2 2 2 1 KIX domain KIX PF02172.16 KHN69431.1 - 0.071 13.4 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 KIX domain SRF-TF PF00319.18 KHN69432.1 - 1.3e-18 66.2 0.2 2.6e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SHS2_Rpb7-N PF03876.17 KHN69433.1 - 1.3e-09 38.3 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KHN69433.1 - 1.4e-07 31.8 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain tRNA-synt_2_TM PF16995.5 KHN69434.1 - 0.013 15.2 1.7 0.017 14.8 1.6 1.3 1 1 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase DUF3792 PF12670.7 KHN69434.1 - 0.062 13.5 8.6 0.076 13.2 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF3671 PF12420.8 KHN69434.1 - 0.075 13.1 1.3 0.13 12.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function PhoLip_ATPase_C PF16212.5 KHN69434.1 - 0.13 12.0 6.2 0.14 11.8 6.2 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Ninjurin PF04923.12 KHN69434.1 - 0.33 10.9 9.4 0.14 12.1 6.2 1.8 1 1 1 2 2 2 0 Ninjurin Glycoprotein_G PF00802.19 KHN69434.1 - 1.1 8.5 3.0 1.4 8.3 3.0 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Latarcin PF10279.9 KHN69435.1 - 0.18 12.2 7.5 0.38 11.2 0.4 3.0 2 2 0 2 2 2 0 Latarcin precursor YlaH PF14036.6 KHN69436.1 - 0.053 13.9 0.2 0.053 13.9 0.2 2.6 3 0 0 3 3 3 0 YlaH-like protein PHO4 PF01384.20 KHN69436.1 - 0.36 9.8 1.8 0.67 9.0 1.8 1.4 1 1 0 1 1 1 0 Phosphate transporter family Annexin PF00191.20 KHN69437.1 - 0.036 14.2 0.8 0.076 13.1 0.8 1.7 1 0 0 1 1 1 0 Annexin DUF4378 PF14309.6 KHN69438.1 - 0.038 14.4 0.1 0.13 12.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) Myb_DNA-binding PF00249.31 KHN69439.1 - 4.4e-26 90.8 5.0 1.2e-11 44.6 0.1 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KHN69439.1 - 2.9e-18 65.9 9.0 7.1e-11 42.2 0.0 4.4 4 1 1 5 5 5 3 Myb-like DNA-binding domain RHD3 PF05879.12 KHN69439.1 - 0.0078 14.4 1.8 0.012 13.8 1.8 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) SLIDE PF09111.10 KHN69439.1 - 0.0095 15.9 0.4 0.16 12.0 0.0 2.9 2 1 1 3 3 3 1 SLIDE MADF_DNA_bdg PF10545.9 KHN69439.1 - 0.017 15.4 0.3 0.017 15.4 0.3 3.0 2 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KHN69439.1 - 0.025 14.7 0.4 0.066 13.3 0.0 2.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 KHN69439.1 - 0.11 12.9 14.8 0.25 11.7 0.7 4.9 2 2 3 5 5 5 0 Myb/SANT-like DNA-binding domain RTC PF01137.21 KHN69440.1 - 1.2e-19 70.4 0.0 1.5e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KHN69440.1 - 3.1e-10 40.5 0.0 6.4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1414 PF07208.11 KHN69440.1 - 7.8 6.6 5.5 1.3 9.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1414) Ribul_P_3_epim PF00834.19 KHN69441.1 - 2.7e-44 150.9 1.5 3.1e-44 150.8 1.5 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family zf-CCCH PF00642.24 KHN69442.1 - 3.8e-08 33.0 2.2 1e-07 31.6 2.2 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 KHN69442.1 - 2.6e-06 27.1 11.0 5.3e-06 26.2 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 KHN69442.1 - 3.6e-06 26.8 3.7 1.1e-05 25.3 3.7 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 KHN69442.1 - 6.7e-06 25.9 11.2 1.5e-05 24.8 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KHN69442.1 - 9.1e-06 25.4 9.3 9.1e-06 25.4 9.3 1.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KHN69442.1 - 9.4e-06 25.9 9.6 9.4e-06 25.9 9.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KHN69442.1 - 9.8e-06 25.5 8.4 2.1e-05 24.5 8.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KHN69442.1 - 7e-05 22.7 11.3 0.00014 21.7 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KHN69442.1 - 0.00065 19.5 7.4 0.0018 18.1 7.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KHN69442.1 - 0.0018 18.4 8.0 0.0042 17.2 8.0 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 KHN69442.1 - 0.0038 17.0 2.4 0.0038 17.0 2.4 2.3 2 0 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 KHN69442.1 - 0.012 16.3 0.5 0.017 15.8 0.5 1.3 1 0 0 1 1 1 0 Torus domain zf-rbx1 PF12678.7 KHN69442.1 - 0.075 13.3 9.2 1.4 9.2 4.7 2.5 1 1 1 2 2 2 0 RING-H2 zinc finger domain Ribosomal_L19e PF01280.20 KHN69443.1 - 1.5e-52 177.5 11.1 1.8e-52 177.2 11.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e SHOCT PF09851.9 KHN69443.1 - 0.00053 19.6 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 Short C-terminal domain Siah-Interact_N PF09032.11 KHN69443.1 - 0.092 13.1 0.8 0.2 12.0 0.8 1.7 1 1 0 1 1 1 0 Siah interacting protein, N terminal Bcr-Abl_Oligo PF09036.10 KHN69443.1 - 0.17 11.9 2.1 0.96 9.5 0.2 2.4 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Evr1_Alr PF04777.13 KHN69444.1 - 1.7e-27 95.8 0.3 2.6e-27 95.2 0.3 1.3 1 0 0 1 1 1 1 Erv1 / Alr family TFIIB PF00382.19 KHN69445.1 - 9.6e-40 134.5 4.1 4.4e-22 77.9 0.6 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KHN69445.1 - 5.5e-13 48.2 2.7 1.3e-12 47.0 2.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 KHN69445.1 - 3.6e-05 23.5 0.4 0.00061 19.5 0.1 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.20 KHN69445.1 - 0.00023 21.2 1.0 0.0011 19.1 0.2 2.1 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain DUF4370 PF14290.6 KHN69445.1 - 0.0072 16.2 0.1 0.083 12.7 0.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4370) TFIIB_C_1 PF18542.1 KHN69445.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Cyclin_C PF02984.19 KHN69445.1 - 0.11 12.5 0.1 1.1 9.4 0.0 2.1 1 1 0 2 2 2 0 Cyclin, C-terminal domain Ribosomal_S13 PF00416.22 KHN69446.1 - 2e-34 118.8 1.7 2.3e-34 118.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KHN69446.1 - 0.0022 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_5 PF14520.6 KHN69446.1 - 0.016 15.8 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain EF-hand_8 PF13833.6 KHN69446.1 - 0.066 13.1 0.0 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Ribosomal_L36e PF01158.18 KHN69447.1 - 3.9e-09 36.6 5.0 4.5e-09 36.4 4.9 1.2 1 1 0 1 1 1 1 Ribosomal protein L36e COG2 PF06148.11 KHN69447.1 - 0.093 12.8 0.3 0.097 12.8 0.3 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LSM PF01423.22 KHN69450.1 - 2.4e-08 33.5 0.0 2.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KHN69450.1 - 0.00087 19.4 0.0 0.00094 19.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KHN69450.1 - 0.0088 16.1 0.9 0.013 15.6 0.9 1.4 1 1 0 1 1 1 1 Scd6-like Sm domain Vps26 PF03643.15 KHN69450.1 - 0.046 12.7 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Gemin6 PF06372.12 KHN69450.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Gemin6 protein zf-H2C2_2 PF13465.6 KHN69451.1 - 8.5e-07 29.1 0.4 8.5e-07 29.1 0.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KHN69451.1 - 2.6e-05 24.4 1.3 2.6e-05 24.4 1.3 3.5 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KHN69451.1 - 0.00013 22.5 0.7 0.00013 22.5 0.7 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KHN69451.1 - 0.0047 16.9 0.3 0.0047 16.9 0.3 2.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-BED PF02892.15 KHN69451.1 - 0.041 13.9 2.9 0.051 13.6 0.3 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2HE PF16278.5 KHN69451.1 - 0.13 12.7 4.3 0.35 11.4 4.3 1.8 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 KHN69451.1 - 0.38 11.4 8.6 2.9 8.6 0.4 3.5 2 2 2 4 4 4 0 FOXP coiled-coil domain Zap1_zf2 PF18217.1 KHN69451.1 - 9.8 6.3 9.2 9.2 6.4 0.4 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 CFAP91 PF14738.6 KHN69453.1 - 0.017 15.2 2.3 0.034 14.2 2.3 1.5 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 YchF-GTPase_C PF06071.13 KHN69454.1 - 3.4e-34 116.9 0.5 7.6e-34 115.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KHN69454.1 - 1.4e-22 79.9 0.0 9e-22 77.3 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KHN69454.1 - 4.8e-09 35.9 0.2 9.5e-08 31.7 0.0 2.5 2 1 1 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 KHN69454.1 - 0.012 16.2 0.1 0.037 14.6 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 KHN69454.1 - 0.1 12.6 1.1 4 7.5 1.1 3.1 1 1 0 1 1 1 0 Dynamin family Ploopntkinase3 PF18751.1 KHN69454.1 - 0.11 12.4 0.0 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 KHN69454.1 - 0.12 11.3 0.0 0.3 10.0 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SAP PF02037.27 KHN69455.1 - 5.3e-09 35.6 0.0 9.9e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF4441 PF14536.6 KHN69455.1 - 0.35 11.1 4.6 0.76 10.0 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4441) Ribosomal_L14e PF01929.17 KHN69457.1 - 0.016 15.6 0.4 0.052 14.0 0.5 1.7 2 0 0 2 2 2 0 Ribosomal protein L14 DUF3863 PF12979.7 KHN69457.1 - 0.054 12.3 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) Med21 PF11221.8 KHN69458.1 - 0.016 15.5 0.1 0.036 14.3 0.0 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex TPR_2 PF07719.17 KHN69459.1 - 1.1e-12 47.0 6.8 0.69 10.2 0.0 8.8 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 KHN69459.1 - 1.2e-05 25.7 4.8 0.24 11.9 0.1 5.8 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69459.1 - 1.4e-05 24.9 13.9 0.42 11.0 0.1 7.8 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 KHN69459.1 - 2.5e-05 24.5 0.0 1.2 9.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KHN69459.1 - 0.00049 19.8 12.7 7.4 6.6 0.0 7.4 9 1 1 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KHN69459.1 - 0.0015 18.7 1.4 45 4.4 0.0 5.6 4 3 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KHN69459.1 - 0.0019 18.9 1.1 66 4.7 0.0 6.1 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KHN69459.1 - 0.0049 17.5 0.0 2 9.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KHN69459.1 - 0.018 14.9 0.5 6.8 6.7 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KHN69459.1 - 0.023 15.1 0.1 6.3 7.4 0.0 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KHN69459.1 - 0.033 14.8 0.1 48 4.9 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TruD PF01142.18 KHN69460.1 - 1.9e-36 125.8 5.5 7.9e-23 80.9 0.7 4.8 3 1 1 4 4 4 4 tRNA pseudouridine synthase D (TruD) DEAD PF00270.29 KHN69462.1 - 9.3e-24 84.1 0.8 8.8e-21 74.4 0.8 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69462.1 - 6.7e-19 68.3 1.2 3.8e-17 62.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69462.1 - 1.8e-07 31.3 0.4 1.1e-06 28.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KHN69462.1 - 0.0039 16.7 0.2 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein Flavi_DEAD PF07652.14 KHN69462.1 - 0.012 15.5 0.7 0.034 14.1 0.1 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain SecA_DEAD PF07517.14 KHN69462.1 - 0.022 14.1 1.1 0.15 11.4 0.0 2.3 1 1 1 2 2 2 0 SecA DEAD-like domain AAA_2 PF07724.14 KHN69462.1 - 0.065 13.3 0.3 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KHN69462.1 - 3 8.1 4.8 1.8e+02 2.3 4.8 2.5 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.19 KHN69463.1 - 8.4e-05 22.9 1.0 0.44 11.0 0.2 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KHN69463.1 - 0.023 15.3 5.5 0.032 14.8 0.8 2.6 2 0 0 2 2 2 0 HMG-box domain DUF1104 PF06518.11 KHN69463.1 - 1.4 9.4 8.3 0.55 10.6 3.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) Jiv90 PF14901.6 KHN69463.1 - 3.2 8.0 9.1 0.23 11.6 1.7 2.5 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone HMG_box PF00505.19 KHN69464.1 - 1.6e-22 79.7 14.9 9.9e-13 48.3 3.1 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KHN69464.1 - 4e-17 62.6 13.0 8.8e-10 39.0 2.1 2.7 2 1 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 KHN69464.1 - 9.8e-06 25.8 6.4 8.6e-05 22.8 0.7 2.1 1 1 1 2 2 2 2 Protamine and protamine like CHDNT PF08073.12 KHN69464.1 - 1.8e-05 24.6 0.1 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 1 CHDNT (NUC034) domain YABBY PF04690.13 KHN69464.1 - 0.00028 21.5 5.1 0.0004 21.0 5.1 1.4 1 1 0 1 1 1 1 YABBY protein COX4 PF02936.14 KHN69464.1 - 0.054 13.5 4.4 0.37 10.8 0.7 2.4 2 1 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KHN69464.1 - 0.12 12.9 8.8 4.2 7.9 2.8 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Nitr_red_assoc PF09655.10 KHN69464.1 - 0.15 12.7 2.3 0.31 11.7 2.3 1.5 1 1 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) APG6_N PF17675.1 KHN69464.1 - 0.28 11.7 11.3 1.4 9.5 5.0 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Dus PF01207.17 KHN69464.1 - 0.44 9.6 5.2 0.32 10.1 3.0 1.7 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) SNAP PF14938.6 KHN69465.1 - 7.1e-10 38.8 7.6 1.4e-09 37.8 6.5 1.8 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KHN69465.1 - 6.6e-05 23.1 1.0 0.27 11.5 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69465.1 - 0.017 15.3 9.4 5.4 7.5 0.1 5.5 3 3 2 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 KHN69465.1 - 0.63 11.0 5.6 2.3e+02 3.4 0.0 5.5 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat TPT PF03151.16 KHN69466.1 - 4.7e-15 55.7 19.7 5.4e-15 55.5 19.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KHN69466.1 - 0.015 15.4 13.0 0.015 15.4 13.0 2.4 2 0 0 2 2 2 0 EamA-like transporter family MtN3_slv PF03083.16 KHN69466.1 - 0.32 11.1 9.2 0.19 11.8 2.1 2.7 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF1129 PF06570.11 KHN69466.1 - 1.7 8.1 8.8 0.74 9.3 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) ATP_bind_1 PF03029.17 KHN69467.1 - 3.1e-31 109.0 0.0 3.4e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KHN69467.1 - 0.0017 18.4 0.0 0.0049 16.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KHN69467.1 - 0.0035 16.6 0.0 0.054 12.8 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 KHN69467.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN69467.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KHN69467.1 - 0.059 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KHN69467.1 - 0.085 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KHN69467.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KHN69467.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KHN69467.1 - 0.22 10.5 0.0 13 4.7 0.0 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RINGv PF12906.7 KHN69468.1 - 1.8e-11 44.0 6.1 2.7e-11 43.4 6.1 1.3 1 0 0 1 1 1 1 RING-variant domain DUF4636 PF15468.6 KHN69468.1 - 0.16 11.7 0.3 0.34 10.6 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4636) DUF996 PF06195.13 KHN69468.1 - 0.31 11.3 6.6 0.63 10.3 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Diphthamide_syn PF01866.17 KHN69470.1 - 3.9e-13 49.5 0.0 9.3e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 Putative diphthamide synthesis protein SIS_2 PF13580.6 KHN69470.1 - 0.071 13.1 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 SIS domain DnaJ PF00226.31 KHN69472.1 - 1.1e-07 31.9 0.1 7.8e-07 29.1 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain DUF4491 PF14898.6 KHN69472.1 - 0.16 12.4 0.2 0.69 10.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4491) DUF4539 PF15072.6 KHN69474.1 - 6.7e-07 29.3 0.1 1.3e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) tRNA_anti-codon PF01336.25 KHN69474.1 - 0.035 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ferritin PF00210.24 KHN69475.1 - 9e-25 87.3 0.1 1.1e-24 86.9 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 KHN69475.1 - 0.0033 17.8 0.2 0.0046 17.3 0.2 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.10 KHN69475.1 - 0.066 13.6 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) FbpA PF05833.11 KHN69476.1 - 6e-30 104.4 4.8 8.5e-30 103.9 4.8 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 KHN69476.1 - 1.5e-24 86.7 0.1 4.2e-24 85.3 0.1 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 KHN69476.1 - 1.1e-15 57.4 0.1 1.1e-15 57.4 0.1 2.5 2 1 0 2 2 2 1 NFACT protein C-terminal domain NFACT-R_2 PF18297.1 KHN69476.1 - 0.03 14.5 0.0 0.29 11.4 0.0 2.5 2 0 0 2 2 2 0 NFACT protein RNA binding domain Hormone_1 PF00103.20 KHN69476.1 - 0.036 13.8 4.0 0.098 12.4 0.1 2.5 2 0 0 2 2 2 0 Somatotropin hormone family ApoLp-III PF07464.11 KHN69476.1 - 0.068 13.3 3.3 14 5.7 0.2 3.5 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF3848 PF12959.7 KHN69476.1 - 0.2 11.7 2.1 1.1 9.3 2.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3848) CDT1 PF08839.11 KHN69477.1 - 6.5e-08 33.1 0.0 1.2e-05 25.7 0.1 2.5 2 0 0 2 2 2 2 DNA replication factor CDT1 like CDT1_C PF16679.5 KHN69477.1 - 0.064 13.7 2.7 0.11 13.0 1.9 1.8 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Sld5 PF05916.11 KHN69478.1 - 1.3e-14 54.6 0.2 1.9e-14 54.1 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein VTC PF09359.10 KHN69479.1 - 1.9e-83 280.1 0.9 1.9e-83 280.1 0.9 1.7 3 0 0 3 3 3 1 VTC domain DUF202 PF02656.15 KHN69479.1 - 5.4e-14 52.4 2.7 9.8e-14 51.6 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KHN69479.1 - 2.3 8.0 10.7 2.8 7.8 1.4 2.4 1 1 0 2 2 2 0 SPX domain TPR_1 PF00515.28 KHN69480.1 - 2.8e-27 93.3 9.0 0.00024 20.8 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KHN69480.1 - 8.5e-24 81.7 4.9 0.0027 17.7 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69480.1 - 5.6e-23 79.2 17.4 0.00018 21.5 1.0 6.5 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KHN69480.1 - 5e-14 51.6 4.3 0.00015 21.9 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 KHN69480.1 - 5.7e-11 42.3 0.0 0.99 10.4 0.0 6.3 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KHN69480.1 - 5.5e-10 38.8 11.0 3.6e-06 26.6 0.0 5.7 3 2 3 6 6 6 3 TPR repeat TPR_12 PF13424.6 KHN69480.1 - 1.1e-09 38.5 5.3 0.024 14.9 0.1 5.7 3 2 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KHN69480.1 - 2e-09 36.8 2.4 0.0099 15.9 0.0 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KHN69480.1 - 4.2e-08 33.7 0.0 0.0034 18.0 0.0 4.1 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KHN69480.1 - 3.2e-07 30.5 9.3 0.13 12.9 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KHN69480.1 - 2.3e-06 28.0 0.0 0.0092 16.5 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KHN69480.1 - 9e-05 21.8 0.0 0.0038 16.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KHN69480.1 - 0.00033 20.8 20.7 0.0013 18.9 0.4 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 KHN69480.1 - 0.0004 19.5 0.3 0.074 12.0 0.2 2.3 1 1 2 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 KHN69480.1 - 0.022 14.6 0.1 19 5.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KHN69480.1 - 0.025 14.8 7.8 1 9.7 0.0 5.4 7 0 0 7 7 5 0 PPR repeat TPR_9 PF13371.6 KHN69480.1 - 0.046 13.9 0.0 8.4 6.6 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 KHN69481.1 - 9.7e-40 136.2 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KHN69481.1 - 8.7e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KHN69481.1 - 3.9e-05 23.7 0.0 0.0002 21.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KHN69481.1 - 0.001 18.5 0.0 0.0064 15.9 0.0 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KHN69481.1 - 0.051 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KHN69481.1 - 0.15 12.0 0.1 0.96 9.3 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Ribosomal_S26e PF01283.19 KHN69482.1 - 1.4e-34 118.8 3.2 1.4e-34 118.7 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e CDC50 PF03381.15 KHN69483.1 - 9.2e-36 123.8 0.0 9.2e-36 123.8 0.0 1.5 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sec1 PF00995.23 KHN69484.1 - 6e-51 174.4 4.4 1.2e-50 173.3 4.4 1.4 1 1 0 1 1 1 1 Sec1 family KH_1 PF00013.29 KHN69485.1 - 8.5e-17 60.7 16.0 3.2e-09 36.5 0.4 4.0 4 0 0 4 4 4 3 KH domain HATPase_c_5 PF14501.6 KHN69485.1 - 0.024 14.5 2.6 0.025 14.5 0.6 2.1 2 0 0 2 2 2 0 GHKL domain AA_permease_2 PF13520.6 KHN69486.1 - 7.2e-28 97.6 40.6 4.4e-27 95.0 40.6 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KHN69486.1 - 2.8e-21 75.6 38.4 8.2e-21 74.1 38.4 1.7 1 1 0 1 1 1 1 Amino acid permease HEAT_2 PF13646.6 KHN69487.1 - 3e-18 66.0 0.0 2.7e-08 34.1 0.0 3.0 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 KHN69487.1 - 3.4e-15 55.1 0.0 0.0015 19.0 0.0 5.4 5 0 0 5 5 5 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KHN69487.1 - 0.0005 20.1 0.0 0.42 11.0 0.0 4.1 5 0 0 5 5 5 1 HEAT repeat SPK PF04435.18 KHN69487.1 - 0.072 13.5 0.1 3.2 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF545) HEAT_EZ PF13513.6 KHN69487.1 - 0.089 13.3 0.0 6.6 7.4 0.0 3.5 4 1 0 4 4 4 0 HEAT-like repeat HlyIII PF03006.20 KHN69488.1 - 2.4e-32 112.4 17.3 2.7e-32 112.3 17.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related Plug_translocon PF10559.9 KHN69488.1 - 0.032 14.1 0.4 0.032 14.1 0.4 2.4 2 0 0 2 2 2 0 Plug domain of Sec61p Fun_ATP-synt_8 PF05933.13 KHN69488.1 - 0.15 12.2 3.5 0.44 10.8 0.0 3.1 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) NOT2_3_5 PF04153.18 KHN69489.1 - 3.4e-33 114.5 9.0 5.4e-33 113.9 9.0 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family NTP_transf_2 PF01909.23 KHN69490.1 - 2.1e-08 34.3 0.0 5.2e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KHN69490.1 - 0.00014 21.9 0.2 0.00054 20.0 0.0 2.1 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase tRNA_NucTransf2 PF09249.11 KHN69490.1 - 0.0061 16.8 0.0 0.03 14.6 0.0 2.2 1 1 0 1 1 1 1 tRNA nucleotidyltransferase, second domain DNA_pol_B_palm PF14792.6 KHN69490.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Lipid_DES PF08557.10 KHN69490.1 - 0.15 11.6 0.4 1.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) PAP_assoc PF03828.19 KHN69490.1 - 10 6.5 8.2 4.7e+02 1.1 8.2 2.8 1 1 0 1 1 1 0 Cid1 family poly A polymerase NDK PF00334.19 KHN69491.1 - 3e-49 166.5 0.0 3.4e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.32 KHN69493.1 - 7.4e-15 55.1 4.4 0.00027 21.7 0.1 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69493.1 - 5e-06 26.7 0.1 4.5 7.6 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KHN69493.1 - 0.0069 15.1 0.8 0.012 14.3 0.7 1.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 ER_lumen_recept PF00810.18 KHN69495.1 - 9.9e-43 146.5 10.1 1.8e-42 145.7 10.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF5360 PF17314.2 KHN69495.1 - 0.024 14.7 2.6 0.039 14.0 1.8 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5360) PQ-loop PF04193.14 KHN69495.1 - 0.032 14.0 6.8 0.08 12.7 0.3 3.3 3 0 0 3 3 3 0 PQ loop repeat PSP1 PF04468.12 KHN69496.1 - 4.7e-28 97.3 3.1 7.9e-28 96.6 3.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF2298 PF10060.9 KHN69499.1 - 0.51 9.0 8.0 0.63 8.7 8.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF3995 PF13160.6 KHN69499.1 - 1.3 9.4 6.5 0.98 9.8 1.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) DUF1129 PF06570.11 KHN69499.1 - 9.9 5.6 15.6 4.3 6.8 13.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) EVI2A PF05399.11 KHN69502.1 - 0.38 10.3 6.9 0.64 9.6 6.9 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MPS-4 PF17523.2 KHN69502.1 - 2.5 8.3 6.8 0.28 11.4 1.0 2.2 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Acetyltransf_1 PF00583.25 KHN69503.1 - 1e-12 48.3 0.1 2.4e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KHN69503.1 - 7.5e-08 32.7 0.1 1.2e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KHN69503.1 - 1.5e-07 31.4 0.5 2.1e-07 30.9 0.5 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KHN69503.1 - 4.6e-05 23.3 0.1 8.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein TRAUB PF08164.12 KHN69504.1 - 0.0013 19.2 1.2 0.0029 18.1 0.0 2.2 2 2 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal DUF3418 PF11898.8 KHN69504.1 - 0.0027 16.5 0.4 0.0034 16.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) CdvA PF18822.1 KHN69504.1 - 0.038 13.8 2.2 0.038 13.8 2.2 2.0 1 1 0 1 1 1 0 CdvA-like coiled-coil domain MRP-L28 PF09812.9 KHN69504.1 - 0.04 14.0 0.6 0.061 13.5 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 KCNQ_channel PF03520.14 KHN69504.1 - 0.059 13.2 2.4 0.15 11.9 2.0 1.7 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel DUF745 PF05335.13 KHN69504.1 - 0.26 11.0 0.5 0.42 10.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF948 PF06103.11 KHN69504.1 - 0.39 11.0 2.8 2.4 8.4 2.8 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF5077 PF16871.5 KHN69506.1 - 0.09 12.7 1.4 0.14 12.0 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5077) AIF_C PF14721.6 KHN69506.1 - 0.5 10.7 5.5 0.24 11.8 2.9 1.7 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GOLD_2 PF13897.6 KHN69506.1 - 0.75 10.3 3.5 0.87 10.1 2.5 1.6 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking PsaL PF02605.15 KHN69507.1 - 0.16 11.6 1.3 0.49 10.0 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI DUF1772 PF08592.11 KHN69507.1 - 0.44 10.9 3.7 8 6.8 3.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Sbt_1 PF05982.12 KHN69507.1 - 0.99 8.6 12.4 0.53 9.5 8.3 2.2 1 1 1 2 2 2 0 Na+-dependent bicarbonate transporter superfamily 5_3_exonuc PF01367.20 KHN69507.1 - 8.2 7.1 7.7 0.54 10.9 0.4 2.8 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold Wzy_C PF04932.15 KHN69508.1 - 1.5 8.5 11.5 0.15 11.7 1.0 2.6 2 2 0 2 2 2 0 O-Antigen ligase MIEAP PF16026.5 KHN69509.1 - 0.004 17.4 0.6 0.0049 17.1 0.6 1.0 1 0 0 1 1 1 1 Mitochondria-eating protein MCPsignal PF00015.21 KHN69509.1 - 0.014 15.2 4.3 0.018 14.8 4.3 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 KHN69509.1 - 0.032 14.6 3.3 0.046 14.1 3.3 1.4 1 0 0 1 1 1 0 Syntaxin-like protein YabA PF06156.13 KHN69509.1 - 0.066 13.8 0.7 0.1 13.2 0.5 1.4 1 1 0 1 1 1 0 Initiation control protein YabA Transketolase_N PF00456.21 KHN69511.1 - 1.2e-96 323.6 0.0 1.6e-96 323.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KHN69511.1 - 1.6e-34 119.1 0.0 4e-34 117.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KHN69511.1 - 0.00076 19.3 0.0 0.0096 15.7 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 KHN69511.1 - 0.0028 17.5 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KHN69511.1 - 0.056 12.7 0.0 0.35 10.0 0.0 2.1 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase zf-RING_UBOX PF13445.6 KHN69512.1 - 1.2e-09 38.1 1.4 1.2e-09 38.1 1.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KHN69512.1 - 1.4e-09 38.1 2.7 1.4e-09 38.1 2.7 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KHN69512.1 - 6e-08 32.4 1.7 6e-08 32.4 1.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KHN69512.1 - 2.6e-06 27.3 2.7 2.6e-06 27.3 2.7 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KHN69512.1 - 5e-06 26.3 2.1 5e-06 26.3 2.1 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KHN69512.1 - 0.00022 21.4 4.9 0.00022 21.4 4.9 3.3 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KHN69512.1 - 0.00048 20.2 1.4 0.00048 20.2 1.4 3.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KHN69512.1 - 0.002 17.8 1.6 0.002 17.8 1.6 4.3 5 0 0 5 5 5 1 RING-like zinc finger zf-Nse PF11789.8 KHN69512.1 - 0.015 15.1 1.1 0.015 15.1 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KHN69512.1 - 0.015 15.1 6.9 0.015 15.1 6.9 3.6 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KHN69512.1 - 3.3 7.8 13.6 0.1 12.7 5.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_1 PF00515.28 KHN69514.1 - 3.4e-10 39.3 14.1 4.6e-05 23.1 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KHN69514.1 - 2.1e-07 30.5 17.5 0.0033 17.4 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KHN69514.1 - 1.6e-06 27.7 0.0 0.43 10.3 0.0 3.9 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 KHN69514.1 - 5e-06 26.7 4.4 0.027 14.7 0.0 4.7 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KHN69514.1 - 1.5e-05 24.8 13.1 0.014 15.6 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KHN69514.1 - 0.0012 19.3 1.4 3.2 8.3 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KHN69514.1 - 0.0019 18.0 0.1 2.3 8.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KHN69514.1 - 0.026 13.8 0.5 0.64 9.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KHN69514.1 - 0.03 15.1 0.0 10 7.2 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KHN69514.1 - 0.068 13.2 0.5 1.8 8.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4116 PF13475.6 KHN69514.1 - 0.15 11.8 5.3 0.96 9.2 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) MIT PF04212.18 KHN69514.1 - 0.5 10.5 7.7 25 5.0 0.0 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KHN69514.1 - 1.2 9.4 18.7 13 6.1 2.4 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Herpes_Helicase PF02689.14 KHN69515.1 - 0.066 11.1 0.3 0.07 11.1 0.3 1.0 1 0 0 1 1 1 0 Helicase DUF4629 PF15442.6 KHN69515.1 - 1.5 9.0 10.5 1.8 8.8 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) O-antigen_lig PF13425.6 KHN69515.1 - 7.5 5.2 6.0 7.3 5.3 6.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YojJ PF10372.9 KHN69517.1 - 0.069 13.3 1.0 0.18 11.9 0.2 2.2 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus GDE_N_bis PF14742.6 KHN69517.1 - 0.21 11.1 1.4 2.6 7.6 1.5 2.0 1 1 1 2 2 2 0 N-terminal domain of (some) glycogen debranching enzymes Baculo_p24 PF05073.12 KHN69517.1 - 0.47 10.2 5.6 0.66 9.7 5.6 1.3 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF1664 PF07889.12 KHN69517.1 - 0.54 10.3 7.6 0.29 11.2 1.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) PUF PF00806.19 KHN69518.1 - 3.7e-06 26.3 1.8 0.72 9.7 0.0 4.6 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat PIF2 PF04631.12 KHN69518.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Per os infectivity factor 2 DUF4125 PF13526.6 KHN69518.1 - 0.017 14.7 0.3 0.067 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) Peptidase_M36 PF02128.15 KHN69518.1 - 0.15 11.2 2.0 0.23 10.6 2.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) DEK_C PF08766.11 KHN69518.1 - 1.6 8.7 4.7 18 5.3 0.3 3.5 4 0 0 4 4 4 0 DEK C terminal domain DUF1242 PF06842.12 KHN69519.1 - 1.2e-07 31.3 0.2 1.8e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Vir_act_alpha_C PF10400.9 KHN69520.1 - 1.2 9.8 9.9 8.1 7.2 0.4 3.9 3 0 0 3 3 3 0 Virulence activator alpha C-term SUV3_C PF12513.8 KHN69520.1 - 9.9 6.2 7.6 3.2 7.8 0.4 3.5 3 0 0 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal PI3K_P85_iSH2 PF16454.5 KHN69521.1 - 0.016 14.8 0.1 0.019 14.5 0.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3673 PF12425.8 KHN69521.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) ATP-synt_C PF00137.21 KHN69522.1 - 6.4e-13 48.8 19.5 7.4e-08 32.6 4.9 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Helicase_C_2 PF13307.6 KHN69523.1 - 5.9e-50 169.8 0.5 9.4e-48 162.6 0.0 2.4 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KHN69523.1 - 4.5e-46 156.7 0.8 8.3e-46 155.8 0.8 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KHN69523.1 - 4.8e-10 39.4 0.7 7.7e-06 25.7 0.4 2.4 1 1 1 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 KHN69523.1 - 4.7e-06 26.7 0.0 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN69523.1 - 3.9e-05 23.5 0.0 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 KHN69523.1 - 0.012 15.1 0.0 0.47 9.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 KHN69523.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN69523.1 - 0.043 14.1 0.2 9.4 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain ASFV_p27 PF06556.11 KHN69523.1 - 0.063 13.4 1.6 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus DUF2075 PF09848.9 KHN69523.1 - 0.16 11.2 0.0 7.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) eIF-5_eIF-2B PF01873.17 KHN69524.1 - 1.9e-28 98.7 0.4 3.2e-28 98.0 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 HEAT PF02985.22 KHN69525.1 - 0.033 14.5 3.4 9 6.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat RTP1_C1 PF10363.9 KHN69525.1 - 0.16 12.1 1.4 1.8 8.8 0.1 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 ACDC PF14733.6 KHN69525.1 - 0.27 11.6 2.1 0.74 10.2 0.3 2.8 2 0 0 2 2 2 0 AP2-coincident C-terminal Ribosomal_L36 PF00444.18 KHN69525.1 - 0.84 9.9 4.8 0.37 11.0 1.5 2.1 2 0 0 2 2 2 0 Ribosomal protein L36 DUF1981 PF09324.10 KHN69525.1 - 2.6 7.9 5.0 47 3.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1981) RRM_1 PF00076.22 KHN69526.1 - 1.4e-10 40.9 0.2 3.6e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4057 PF13266.6 KHN69526.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) PTP2 PF17022.5 KHN69527.1 - 2.2e-21 76.5 11.8 3e-21 76.0 11.8 1.1 1 0 0 1 1 1 1 Polar tube protein 2 from Microsporidia Collagen PF01391.18 KHN69528.1 - 0.68 9.7 4.5 5.4 6.9 0.1 3.4 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) E2F_TDP PF02319.20 KHN69529.1 - 2.4e-14 53.1 1.4 3.7e-14 52.5 0.3 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 KHN69529.1 - 3.5e-11 43.2 2.7 6.6e-11 42.3 2.7 1.5 1 0 0 1 1 1 1 Transcription factor DP Sybindin PF04099.12 KHN69530.1 - 7.1e-16 58.4 0.8 9.5e-16 58.0 0.8 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KHN69530.1 - 6.2e-05 23.1 0.4 8.3e-05 22.7 0.4 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NADHdh-2_N PF12155.8 KHN69530.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal tRNA-synt_1g PF09334.11 KHN69531.1 - 8e-21 74.2 0.2 4.5e-09 35.5 0.0 2.9 2 1 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KHN69531.1 - 3.6e-20 71.8 0.3 1.1e-11 43.8 0.0 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KHN69531.1 - 2.7e-09 36.8 0.0 1.9e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-CCCH_3 PF15663.5 KHN69532.1 - 9.7e-20 70.8 14.1 9.7e-20 70.8 14.1 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 KHN69532.1 - 0.0021 17.9 6.6 0.51 10.3 0.2 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Paramecium_SA PF01508.16 KHN69532.1 - 2.5 8.6 22.7 0.14 12.6 13.6 2.7 2 1 0 2 2 2 0 Paramecium surface antigen domain TGT PF01702.18 KHN69534.1 - 2e-115 385.7 0.0 2.5e-115 385.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RNA_pol_N PF01194.17 KHN69535.1 - 3.2e-28 97.8 1.6 3.8e-28 97.6 1.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KHN69535.1 - 0.0013 18.9 0.4 0.0018 18.5 0.4 1.3 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.6 KHN69535.1 - 0.015 15.3 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 YhfH-like protein Rotamase PF00639.21 KHN69536.1 - 2.1e-20 73.4 0.0 2.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KHN69536.1 - 1.3e-15 57.9 0.0 1.9e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KHN69536.1 - 0.00039 21.3 0.0 0.00061 20.6 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KHN69536.1 - 0.034 14.2 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 WW domain MCM PF00493.23 KHN69537.1 - 1.3e-97 325.3 0.0 2.2e-97 324.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN69537.1 - 1.4e-33 115.4 2.0 3.1e-33 114.3 2.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KHN69537.1 - 4e-29 100.9 4.2 1.1e-28 99.5 4.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KHN69537.1 - 1.3e-08 34.5 0.1 3.2e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KHN69537.1 - 2.5e-08 34.4 0.3 6.7e-08 33.1 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 KHN69537.1 - 0.00015 21.6 0.0 0.0007 19.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KHN69537.1 - 0.00016 21.7 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 KHN69537.1 - 0.00047 20.7 0.7 0.0012 19.4 0.2 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal TFA2_Winged_2 PF18121.1 KHN69538.1 - 2.3e-20 72.0 0.1 2.3e-20 72.0 0.1 2.2 2 1 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KHN69538.1 - 1.2e-11 44.7 2.2 1.2e-11 44.7 2.2 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain tRNA_anti-codon PF01336.25 KHN69539.1 - 5.4e-09 35.9 0.0 9.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 KHN69539.1 - 0.00028 21.5 0.2 0.0014 19.2 0.2 2.1 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti_2 PF13742.6 KHN69539.1 - 0.022 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain ANAPC4_WD40 PF12894.7 KHN69540.1 - 0.0089 16.3 0.2 4.1 7.8 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Reprolysin_3 PF13582.6 KHN69541.1 - 0.00011 22.8 0.2 0.00026 21.5 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KHN69541.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KHN69541.1 - 0.00022 21.4 0.0 0.00044 20.4 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.19 KHN69541.1 - 0.0012 18.8 0.2 0.003 17.5 0.0 1.8 2 0 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.24 KHN69541.1 - 0.019 14.8 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KHN69541.1 - 0.03 14.2 0.6 0.046 13.6 0.2 1.7 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4215 PF13948.6 KHN69541.1 - 9.2 6.8 15.6 0.12 12.9 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) RIO1 PF01163.22 KHN69543.1 - 1.2e-14 54.3 0.3 1.6e-14 53.9 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KHN69543.1 - 1.1e-07 31.4 0.0 1.5e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KHN69543.1 - 1.5e-07 31.1 1.1 2e-07 30.7 1.1 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KHN69543.1 - 6.5e-07 29.5 0.0 7.8e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KHN69543.1 - 1.1e-05 24.9 0.4 1.5e-05 24.4 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 KHN69543.1 - 0.00083 18.8 0.1 0.001 18.5 0.1 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KHN69543.1 - 0.0099 15.5 0.1 1.7 8.2 0.0 2.0 1 1 1 2 2 2 2 Choline/ethanolamine kinase PI-PLC-X PF00388.19 KHN69543.1 - 0.088 12.4 0.3 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain CAP_GLY PF01302.25 KHN69544.1 - 1.2e-24 86.1 0.5 2.3e-24 85.2 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain SlyX PF04102.12 KHN69544.1 - 0.079 13.6 0.3 0.15 12.7 0.3 1.5 1 0 0 1 1 1 0 SlyX MscS_porin PF12795.7 KHN69544.1 - 0.093 12.3 1.3 0.13 11.8 1.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF5101 PF17031.5 KHN69544.1 - 0.21 11.7 3.2 0.29 11.3 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5101) Shugoshin_N PF07558.11 KHN69544.1 - 2.2 8.2 5.4 0.88 9.5 2.1 2.2 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GvpG PF05120.12 KHN69545.1 - 0.14 12.2 0.4 0.23 11.5 0.1 1.5 2 0 0 2 2 2 0 Gas vesicle protein G RIBIOP_C PF04950.12 KHN69546.1 - 6.6e-66 222.7 1.8 6.6e-66 222.7 1.8 2.4 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KHN69546.1 - 2.7e-15 56.2 1.3 1.4e-12 47.5 0.2 3.7 2 1 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 KHN69546.1 - 0.0012 18.5 6.3 0.0049 16.4 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KHN69546.1 - 0.0012 18.9 0.2 0.029 14.5 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KHN69546.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KHN69546.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KHN69546.1 - 0.08 13.4 0.0 0.08 13.4 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KHN69546.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain dUTPase PF00692.19 KHN69547.1 - 9.8e-30 102.9 0.0 1.2e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase Lactamase_B_2 PF12706.7 KHN69548.1 - 6e-17 61.8 0.1 1.8e-16 60.3 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KHN69548.1 - 3.4e-08 33.0 0.0 6.2e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KHN69548.1 - 4e-08 33.5 0.0 1e-07 32.2 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KHN69548.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PDEase_II PF02112.15 KHN69548.1 - 0.016 14.3 0.2 0.039 13.1 0.2 1.6 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II eIF2A PF08662.11 KHN69549.1 - 0.00019 21.4 2.6 0.00075 19.4 0.6 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SPRY PF00622.28 KHN69549.1 - 0.075 13.2 0.5 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 SPRY domain HPS3_N PF14761.6 KHN69549.1 - 0.15 11.5 2.7 14 5.1 0.1 3.7 2 2 2 4 4 4 0 Hermansky-Pudlak syndrome 3 DUF3294 PF07957.11 KHN69549.1 - 0.27 11.0 3.1 4.7 6.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3294) Acetyltransf_1 PF00583.25 KHN69550.1 - 1.1e-10 41.8 0.1 1.5e-06 28.4 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KHN69550.1 - 3.3e-09 37.0 0.4 5.8e-09 36.3 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KHN69550.1 - 8.5e-08 32.2 0.1 2.7e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KHN69550.1 - 0.00011 22.1 0.1 0.09 12.8 0.0 2.3 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_15 PF17013.5 KHN69550.1 - 0.017 14.6 0.1 0.023 14.2 0.1 1.3 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 KHN69550.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3626 PF12294.8 KHN69550.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Nucleoporin_N PF08801.11 KHN69551.1 - 1.2e-16 60.5 0.1 1.9e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KHN69551.1 - 0.18 10.5 0.2 12 4.5 0.0 2.3 1 1 1 2 2 2 0 Non-repetitive/WGA-negative nucleoporin C-terminal Porin_3 PF01459.22 KHN69552.1 - 8e-25 87.8 0.1 9.4e-25 87.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Lyase_catalyt PF09093.11 KHN69552.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic Cpn60_TCP1 PF00118.24 KHN69553.1 - 3.2e-112 375.7 4.4 3.9e-111 372.1 4.4 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family NIBRIN_BRCT_II PF16508.5 KHN69553.1 - 0.11 12.8 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Tub PF01167.18 KHN69555.1 - 5.5e-37 127.8 0.1 1.2e-34 120.2 0.1 2.8 1 1 0 1 1 1 1 Tub family Sel1 PF08238.12 KHN69556.1 - 3e-26 91.2 12.7 2.8e-06 27.8 0.1 7.3 8 0 0 8 8 8 6 Sel1 repeat CRISPR_Cas9_WED PF18061.1 KHN69556.1 - 0.15 12.1 1.3 0.26 11.3 1.3 1.4 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain DUF3262 PF11660.8 KHN69559.1 - 0.094 13.1 0.7 0.094 13.1 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3262) DUF3482 PF11981.8 KHN69560.1 - 0.23 10.8 0.4 0.31 10.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ARL2_Bind_BART PF11527.8 KHN69561.1 - 0.034 14.2 0.7 0.25 11.4 0.4 2.5 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Suf PF05843.14 KHN69561.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.7 2 2 2 4 4 4 0 Suppressor of forked protein (Suf) S1 PF00575.23 KHN69561.1 - 0.72 10.2 6.4 20 5.6 0.1 4.5 4 0 0 4 4 4 0 S1 RNA binding domain Ribosomal_L14 PF00238.19 KHN69561.1 - 0.76 9.9 5.9 2.1 8.4 0.4 3.4 1 1 1 2 2 2 0 Ribosomal protein L14p/L23e RNA_pol_A_bac PF01000.26 KHN69562.1 - 1.9e-27 95.8 0.0 4.1e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KHN69562.1 - 8.4e-17 60.4 0.0 1.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MTS PF05175.14 KHN69563.1 - 6.6e-05 22.5 0.3 0.00028 20.5 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KHN69563.1 - 0.079 12.8 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_His PF13393.6 KHN69564.1 - 1.6e-39 136.0 0.0 1.9e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KHN69564.1 - 1.4e-11 44.4 0.4 4e-11 42.9 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KHN69564.1 - 4.3e-05 23.6 1.5 0.00014 21.9 1.5 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 KHN69564.1 - 0.00023 20.8 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 KHN69564.1 - 0.0028 17.2 0.1 0.011 15.2 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 KHN69564.1 - 0.043 12.9 0.1 0.4 9.7 0.0 2.4 2 1 1 3 3 3 0 tRNA synthetases class II (D, K and N) ADK PF00406.22 KHN69566.1 - 9.3e-42 142.7 0.0 1.1e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KHN69566.1 - 1.1e-25 90.7 0.1 1.4e-25 90.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KHN69566.1 - 1.6e-07 31.2 0.1 0.015 15.0 0.1 2.0 1 1 1 2 2 2 2 Thymidylate kinase AAA_18 PF13238.6 KHN69566.1 - 3.3e-07 30.9 0.1 7.5e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KHN69566.1 - 1.6e-05 25.1 0.1 0.00014 22.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KHN69566.1 - 0.0016 18.3 0.3 0.0097 15.8 0.1 2.0 2 0 0 2 2 2 1 Deoxynucleoside kinase SKI PF01202.22 KHN69566.1 - 0.0085 16.2 0.5 0.021 15.0 0.5 1.8 1 1 0 1 1 1 1 Shikimate kinase ABC_tran PF00005.27 KHN69566.1 - 0.026 15.0 0.0 0.034 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Ploopntkinase1 PF18748.1 KHN69566.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 PAS_7 PF12860.7 KHN69566.1 - 0.035 14.3 0.1 0.069 13.3 0.1 1.4 1 0 0 1 1 1 0 PAS fold Rad17 PF03215.15 KHN69566.1 - 0.054 13.4 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain CoaE PF01121.20 KHN69566.1 - 0.065 12.9 0.3 1.4 8.6 0.1 2.0 1 1 1 2 2 2 0 Dephospho-CoA kinase 53-BP1_Tudor PF09038.10 KHN69567.1 - 0.0021 18.0 0.1 0.0084 16.1 0.1 2.0 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor PH PF00169.29 KHN69568.1 - 3.9e-08 33.7 1.9 7.6e-08 32.8 1.9 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KHN69568.1 - 8.8e-06 26.1 3.0 8.8e-06 26.1 3.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF5094 PF17015.5 KHN69569.1 - 1e-50 172.3 9.4 1.2e-50 172.1 9.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) HZS_alpha PF18582.1 KHN69569.1 - 0.074 13.5 0.1 0.25 11.8 0.1 1.9 1 1 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain Vac14_Fab1_bd PF12755.7 KHN69570.1 - 0.05 14.2 2.6 0.39 11.3 0.2 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RAI16-like PF10257.9 KHN69571.1 - 0.016 14.1 0.5 2.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Retinoic acid induced 16-like protein DASH_Dad4 PF08650.10 KHN69571.1 - 0.092 12.7 3.0 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad4 PTPA PF03095.15 KHN69572.1 - 2.4e-49 168.4 2.8 8.4e-44 150.2 1.2 2.7 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein Ribonuc_red_sm PF00268.21 KHN69573.1 - 5e-112 373.9 1.0 5.9e-112 373.7 1.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Adaptin_N PF01602.20 KHN69575.1 - 8e-15 54.4 1.0 8e-15 54.4 1.0 2.3 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.6 KHN69575.1 - 0.013 15.9 0.0 0.18 12.2 0.0 2.6 1 1 2 3 3 3 0 HEAT repeats Symplekin_C PF12295.8 KHN69576.1 - 1.9e-15 57.4 1.1 1.9e-15 57.4 1.1 2.1 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal tRNA-synt_2 PF00152.20 KHN69577.1 - 3.7e-66 223.4 0.0 4.6e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KHN69577.1 - 6.2e-06 26.1 0.2 1.3e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CcmD PF04995.14 KHN69578.1 - 0.033 14.3 1.2 0.13 12.4 1.2 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4477 PF14780.6 KHN69579.1 - 2.6e-05 23.9 0.3 0.014 15.0 0.4 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) SNF2_N PF00176.23 KHN69580.1 - 9.1e-26 90.4 0.0 1.8e-25 89.4 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KHN69580.1 - 3.3e-13 50.0 0.0 9.2e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69580.1 - 8e-08 32.5 0.0 2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN69580.1 - 0.0036 17.1 0.0 0.026 14.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ArdA PF07275.11 KHN69580.1 - 0.019 15.6 0.1 4.7 7.8 0.0 2.8 3 0 0 3 3 3 0 Antirestriction protein (ArdA) AAA_22 PF13401.6 KHN69580.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TK PF00265.18 KHN69580.1 - 0.1 12.4 0.7 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase AAA_25 PF13481.6 KHN69580.1 - 0.15 11.6 0.0 3.4 7.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain RINGv PF12906.7 KHN69581.1 - 6.1e-14 51.9 6.9 6.1e-14 51.9 6.9 2.1 2 0 0 2 2 2 1 RING-variant domain NCBP3 PF10309.9 KHN69581.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 zf-RING_4 PF14570.6 KHN69581.1 - 2.1 8.2 6.5 6.6 6.6 6.5 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ssu72 PF04722.13 KHN69582.1 - 2.6e-60 203.3 0.2 3.1e-60 203.0 0.2 1.0 1 0 0 1 1 1 1 Ssu72-like protein GTP_EFTU_D2 PF03144.25 KHN69583.1 - 0.029 14.8 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Yop-YscD_cpl PF16697.5 KHN69584.1 - 0.00013 22.2 2.0 0.00038 20.7 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 KHN69584.1 - 0.004 17.5 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 FHA domain RNase_J_C PF17770.1 KHN69584.1 - 0.039 15.0 1.6 0.039 15.0 1.6 4.1 2 1 3 5 5 5 0 Ribonuclease J C-terminal domain DnaJ PF00226.31 KHN69585.1 - 5.5e-08 32.8 0.1 9.5e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KHN69585.1 - 1e-06 28.1 0.1 1.5e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF1910 PF08928.10 KHN69585.1 - 0.0016 18.4 0.1 0.0063 16.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1910) Cullin_Nedd8 PF10557.9 KHN69586.1 - 2.9e-06 27.2 3.7 3.2e-06 27.1 0.6 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 KHN69586.1 - 0.00015 22.1 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Penicillinase repressor Arg_repressor_C PF02863.18 KHN69587.1 - 0.028 14.3 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Form-deh_trans PF09163.11 KHN69587.1 - 0.27 11.0 0.1 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Ribosomal_L5e PF17144.4 KHN69588.1 - 2.6e-68 229.1 1.0 2.6e-68 229.1 1.0 2.0 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KHN69588.1 - 2.6e-26 92.4 8.3 2.6e-26 92.4 8.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Lsr2 PF11774.8 KHN69588.1 - 0.18 11.9 2.7 2.6 8.2 0.1 2.7 3 0 0 3 3 3 0 Lsr2 UCH PF00443.29 KHN69589.1 - 1.4e-40 139.4 0.0 2.1e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KHN69589.1 - 3.1e-07 30.3 0.6 0.0038 16.9 0.1 2.9 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DEAD PF00270.29 KHN69590.1 - 3.4e-23 82.3 0.0 2.4e-22 79.5 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Sec63 PF02889.16 KHN69590.1 - 6.4e-18 64.8 0.7 3.1e-10 39.7 0.0 2.9 2 1 0 2 2 2 2 Sec63 Brl domain Helicase_C PF00271.31 KHN69590.1 - 2.9e-10 40.4 0.0 1.1e-09 38.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69590.1 - 1.5e-08 34.8 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KHN69590.1 - 0.011 16.0 1.9 0.64 10.3 1.4 3.4 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KHN69590.1 - 0.047 12.7 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 KHN69590.1 - 0.064 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF5359 PF17313.2 KHN69590.1 - 0.11 12.6 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5359) IstB_IS21 PF01695.17 KHN69590.1 - 0.11 12.2 0.0 0.88 9.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF4535 PF15054.6 KHN69590.1 - 0.14 11.9 0.1 0.44 10.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) PhoLip_ATPase_C PF16212.5 KHN69591.1 - 3.8e-46 157.9 24.5 3.8e-46 157.9 24.5 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KHN69591.1 - 4.9e-17 61.4 3.8 4.9e-17 61.4 3.8 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KHN69591.1 - 6.4e-15 56.0 0.1 3e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KHN69591.1 - 1.9e-09 37.3 5.6 2.6e-09 36.9 0.0 2.9 2 1 1 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KHN69591.1 - 9.3e-06 25.6 0.0 0.0002 21.4 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KHN69591.1 - 7.4e-05 22.6 0.1 0.00076 19.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FxsA PF04186.13 KHN69591.1 - 0.047 13.8 0.0 7 6.8 0.0 3.1 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein PMT PF02366.18 KHN69592.1 - 0.0017 18.0 8.9 0.0017 18.0 8.9 3.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase BTD PF09270.10 KHN69592.1 - 0.0046 17.2 0.1 0.0093 16.2 0.1 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Guanylate_cyc PF00211.20 KHN69593.1 - 9.8e-08 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FYRN PF05964.14 KHN69594.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 F/Y-rich N-terminus DUF667 PF05018.13 KHN69595.1 - 0.19 11.5 1.9 14 5.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF667) Cpn60_TCP1 PF00118.24 KHN69596.1 - 1.1e-142 476.2 8.7 1.3e-142 475.9 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 KHN69596.1 - 0.015 15.4 0.2 0.075 13.1 0.1 2.1 2 0 0 2 2 2 0 Resolvase, N terminal domain Zn_peptidase PF04228.13 KHN69596.1 - 0.072 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase CNOT1_HEAT PF16418.5 KHN69597.1 - 0.065 13.3 0.1 0.35 10.9 0.1 1.9 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Pkinase PF00069.25 KHN69598.1 - 9.9e-28 97.2 0.0 1.2e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69598.1 - 1.8e-14 53.7 0.0 2.1e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69598.1 - 0.089 12.1 0.0 7.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like AAA PF00004.29 KHN69599.1 - 2e-46 157.7 0.0 3.9e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KHN69599.1 - 1.6e-09 37.6 0.2 6.6e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KHN69599.1 - 4.3e-09 36.0 0.0 8.2e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KHN69599.1 - 2.4e-08 34.3 0.0 6.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KHN69599.1 - 5.9e-08 32.8 0.1 1.8e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KHN69599.1 - 2e-07 31.5 0.1 3e-05 24.5 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 KHN69599.1 - 1.2e-05 25.9 0.0 4.1e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN69599.1 - 1.8e-05 25.0 1.4 0.0051 17.1 1.4 2.5 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KHN69599.1 - 5e-05 23.3 0.2 0.00059 19.8 0.0 2.5 3 0 0 3 3 3 1 NTPase DUF815 PF05673.13 KHN69599.1 - 5.2e-05 22.5 0.0 8.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KHN69599.1 - 0.00026 20.8 0.0 0.0006 19.6 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KHN69599.1 - 0.00072 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KHN69599.1 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KHN69599.1 - 0.0012 19.2 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KHN69599.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KHN69599.1 - 0.0025 18.1 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KHN69599.1 - 0.0026 17.5 0.0 0.0095 15.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KHN69599.1 - 0.0028 16.9 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 KHN69599.1 - 0.0043 16.9 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KHN69599.1 - 0.0056 16.1 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KHN69599.1 - 0.0058 16.0 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 KHN69599.1 - 0.0063 16.3 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KHN69599.1 - 0.0066 16.0 0.0 0.021 14.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 KHN69599.1 - 0.0077 15.9 0.1 0.088 12.5 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KHN69599.1 - 0.01 15.8 0.1 0.1 12.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KHN69599.1 - 0.011 15.7 0.7 0.23 11.4 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 KHN69599.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 KHN69599.1 - 0.022 14.0 0.0 0.31 10.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 KHN69599.1 - 0.027 14.8 0.2 0.081 13.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KHN69599.1 - 0.036 14.6 0.1 0.12 12.9 0.0 2.0 2 1 0 2 2 1 0 ABC transporter AAA_25 PF13481.6 KHN69599.1 - 0.039 13.5 1.2 0.36 10.4 0.1 2.1 1 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KHN69599.1 - 0.043 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 KHN69599.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KHN69599.1 - 0.15 11.2 0.0 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 KHN69599.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF465 PF04325.13 KHN69599.1 - 0.64 10.1 4.0 1.3 9.1 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Adenine_glyco PF03352.13 KHN69600.1 - 0.024 14.4 1.9 0.034 13.9 1.9 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase Pet20 PF08692.10 KHN69600.1 - 0.11 13.2 0.2 0.12 13.0 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet20 ATP-synt_D PF01813.17 KHN69601.1 - 2.7e-54 184.0 4.3 3e-54 183.8 4.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D DUF4315 PF14193.6 KHN69601.1 - 0.033 14.2 1.5 0.07 13.2 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) HALZ PF02183.18 KHN69601.1 - 0.052 13.8 1.2 0.052 13.8 1.2 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper CLZ PF16526.5 KHN69601.1 - 0.078 13.4 2.7 0.16 12.4 1.7 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ARS2 PF04959.13 KHN69602.1 - 3.4e-05 24.3 4.4 5.7e-05 23.6 4.4 1.3 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KHN69602.1 - 7.5e-05 22.4 4.8 0.025 14.4 2.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4187) zf-C2H2_4 PF13894.6 KHN69602.1 - 0.0084 16.9 1.1 0.03 15.1 1.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 KHN69602.1 - 0.015 15.5 0.9 0.04 14.2 0.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 KHN69602.1 - 0.023 14.6 5.0 0.03 14.2 3.1 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FRB_dom PF08771.11 KHN69602.1 - 0.047 14.1 1.9 0.054 13.9 0.6 1.8 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain zf-C2H2 PF00096.26 KHN69602.1 - 0.15 12.6 1.8 0.47 11.0 1.8 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.14 KHN69602.1 - 0.16 11.8 5.1 0.076 12.9 2.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-CHC2 PF01807.20 KHN69602.1 - 0.5 10.2 6.0 7.1 6.5 0.8 2.4 2 0 0 2 2 2 0 CHC2 zinc finger DUF3546 PF12066.8 KHN69602.1 - 0.87 9.8 7.1 0.083 13.1 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3546) DUF3970 PF13113.6 KHN69602.1 - 2.4 8.4 5.2 0.28 11.4 0.3 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3970) zf-C2H2_2 PF12756.7 KHN69602.1 - 3.6 8.0 11.2 17 5.8 9.1 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_L23 PF00276.20 KHN69603.1 - 4.8e-14 52.5 3.3 9.4e-14 51.5 3.3 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 GRDB PF07355.12 KHN69603.1 - 0.027 13.7 0.2 0.034 13.4 0.2 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) adh_short PF00106.25 KHN69603.1 - 0.028 13.9 0.1 0.032 13.7 0.1 1.1 1 0 0 1 1 1 0 short chain dehydrogenase SRP54 PF00448.22 KHN69604.1 - 1.2e-51 175.1 0.1 1.9e-51 174.5 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KHN69604.1 - 8.5e-06 24.9 0.1 2.9e-05 23.2 0.1 1.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KHN69604.1 - 9.7e-05 22.4 0.0 0.0015 18.6 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KHN69604.1 - 0.00091 19.2 0.1 0.05 13.5 0.1 2.5 1 1 0 1 1 1 1 NTPase AAA PF00004.29 KHN69604.1 - 0.0015 19.0 0.1 0.085 13.3 0.0 2.5 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KHN69604.1 - 0.0019 17.9 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain VirC1 PF07015.11 KHN69604.1 - 0.0034 16.7 0.0 0.008 15.5 0.0 1.5 1 1 0 1 1 1 1 VirC1 protein MMR_HSR1 PF01926.23 KHN69604.1 - 0.0041 17.2 0.2 0.026 14.6 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54_N PF02881.19 KHN69604.1 - 0.0063 16.7 0.6 0.041 14.1 0.5 2.5 2 1 1 3 3 3 1 SRP54-type protein, helical bundle domain AAA_24 PF13479.6 KHN69604.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KHN69604.1 - 0.01 16.2 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN69604.1 - 0.025 14.8 0.1 0.1 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KHN69604.1 - 0.027 14.4 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KHN69604.1 - 0.034 13.6 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 3HCDH_RFF PF18321.1 KHN69604.1 - 0.048 14.1 0.0 2.1 8.8 0.0 2.6 3 0 0 3 3 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain CLP1_P PF16575.5 KHN69604.1 - 0.058 13.2 0.1 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 KHN69604.1 - 0.19 11.6 1.6 2.1 8.2 0.1 2.8 3 1 0 3 3 3 0 RsgA GTPase Rib_5-P_isom_A PF06026.14 KHN69605.1 - 1.3e-40 138.8 0.0 1.5e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KHN69605.1 - 0.012 15.5 0.5 0.53 10.2 0.1 2.2 1 1 1 2 2 2 0 DeoR C terminal sensor domain DUF2683 PF10884.8 KHN69605.1 - 0.097 12.9 0.0 0.53 10.6 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2683) RPN7 PF10602.9 KHN69606.1 - 1.1e-32 113.1 0.2 2.1e-32 112.2 0.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KHN69606.1 - 3.2e-13 50.1 0.5 6.4e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 PCI domain Tox-REase-2 PF15646.6 KHN69606.1 - 0.091 12.9 1.1 2.3 8.4 0.2 2.8 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 2 Nop PF01798.18 KHN69607.1 - 2.4e-06 27.2 0.5 7.4e-06 25.6 0.0 2.0 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin RNA_pol_Rpc34 PF05158.12 KHN69608.1 - 2e-44 152.4 1.2 2.2e-43 149.0 1.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KHN69608.1 - 0.004 17.8 0.0 0.24 12.1 0.0 2.6 3 0 0 3 3 3 1 Replication protein A C terminal DUF433 PF04255.14 KHN69608.1 - 0.056 13.3 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Rrf2 PF02082.20 KHN69608.1 - 0.062 13.7 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator WD40 PF00400.32 KHN69609.1 - 5.2e-10 39.8 7.6 0.018 15.9 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69609.1 - 6.9e-05 23.1 0.3 0.25 11.6 0.0 3.9 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KHN69609.1 - 0.036 13.6 0.0 0.089 12.4 0.0 1.6 1 1 0 1 1 1 0 PQQ-like domain Tcp10_C PF07202.13 KHN69610.1 - 1.1e-05 25.5 0.8 2.3e-05 24.4 0.7 1.6 1 1 0 1 1 1 1 T-complex protein 10 C-terminus Yuri_gagarin PF15934.5 KHN69610.1 - 0.0036 17.2 2.1 0.0044 16.9 2.1 1.0 1 0 0 1 1 1 1 Yuri gagarin DUF1655 PF07868.11 KHN69610.1 - 0.034 14.2 2.3 0.24 11.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1655) Not3 PF04065.15 KHN69610.1 - 0.11 11.9 4.8 0.11 11.9 4.0 1.4 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component TTRAP PF14203.6 KHN69610.1 - 0.21 11.6 1.0 0.39 10.7 1.0 1.4 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein TssO PF17561.2 KHN69610.1 - 0.52 10.4 5.3 0.97 9.5 1.8 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssO Cpn60_TCP1 PF00118.24 KHN69611.1 - 3.4e-142 474.6 10.4 3.8e-142 474.4 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpb2_6 PF00562.28 KHN69612.1 - 1e-129 433.1 0.0 1.5e-129 432.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KHN69612.1 - 2.3e-58 197.0 0.1 3.7e-58 196.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KHN69612.1 - 1.1e-42 145.9 0.0 1.7e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KHN69612.1 - 2.5e-32 111.1 0.0 1.8e-31 108.4 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KHN69612.1 - 1.1e-26 92.8 0.0 2.4e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KHN69612.1 - 1.9e-22 79.3 0.2 6.6e-22 77.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 KHN69612.1 - 2.9e-17 63.0 2.1 3.1e-17 62.9 0.6 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MlaD PF02470.20 KHN69612.1 - 0.091 13.1 0.2 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 MlaD protein CBFD_NFYB_HMF PF00808.23 KHN69613.1 - 7.3e-21 74.2 4.6 9.1e-21 73.9 4.6 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KHN69613.1 - 0.0011 19.3 0.1 0.0017 18.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KHN69613.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.4 1 1 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KHN69613.1 - 0.049 13.7 0.2 0.063 13.4 0.2 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Caprin-1_dimer PF18293.1 KHN69613.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Caprin-1 dimerization domain RNase_PH PF01138.21 KHN69614.1 - 3.8e-14 53.3 0.0 9.2e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 DUF5421 PF17458.2 KHN69614.1 - 0.23 10.8 0.1 0.41 10.0 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5421) GNAT_acetyltr_2 PF13718.6 KHN69615.1 - 1.7e-62 210.8 0.0 3.4e-62 209.8 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 KHN69615.1 - 2.2e-51 174.2 0.1 5.8e-51 172.8 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KHN69615.1 - 2.8e-25 88.1 0.3 4.3e-24 84.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 KHN69615.1 - 2.2e-20 73.4 1.0 2.2e-20 73.4 1.0 2.3 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.25 KHN69615.1 - 0.0039 17.4 0.0 0.0096 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_30 PF13604.6 KHN69615.1 - 0.016 15.0 0.1 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Acetyltransf_7 PF13508.7 KHN69615.1 - 0.017 15.5 0.0 0.057 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_19 PF13245.6 KHN69615.1 - 0.033 14.5 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain Sigma_reg_C PF13791.6 KHN69615.1 - 0.073 13.3 0.1 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator C-terminal zf-U1 PF06220.12 KHN69616.1 - 1.4e-13 50.3 2.0 1.9e-13 49.9 2.0 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.7 KHN69616.1 - 0.076 13.4 5.2 1.8 9.0 5.2 2.3 1 1 0 1 1 1 0 Zinc-finger of C2H2 type MBOAT PF03062.19 KHN69617.1 - 4.6e-17 62.4 23.7 5.6e-17 62.1 23.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KHN69617.1 - 0.0002 21.6 3.8 0.0002 21.6 3.8 2.7 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Acyltransferase PF01553.21 KHN69618.1 - 3.4e-12 46.1 0.0 8.7e-12 44.8 0.1 1.6 2 0 0 2 2 2 1 Acyltransferase Kinesin PF00225.23 KHN69619.1 - 5.3e-95 318.1 3.5 5.3e-95 318.1 3.5 1.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KHN69619.1 - 3.4e-41 140.7 0.8 8.6e-41 139.3 0.2 2.0 1 1 0 1 1 1 1 Microtubule binding Zeta_toxin PF06414.12 KHN69619.1 - 0.038 13.3 0.3 0.16 11.2 0.0 2.1 2 1 1 3 3 3 0 Zeta toxin DUF1759 PF03564.15 KHN69619.1 - 0.061 13.3 2.5 9.8 6.1 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) rve_3 PF13683.6 KHN69619.1 - 0.073 12.9 0.7 4.1 7.3 0.0 3.0 1 1 1 3 3 3 0 Integrase core domain YabA PF06156.13 KHN69619.1 - 0.19 12.3 8.8 8.8 7.0 3.1 4.1 4 0 0 4 4 4 0 Initiation control protein YabA DUF87 PF01935.17 KHN69619.1 - 0.28 11.2 5.2 7.1 6.6 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain DUF3450 PF11932.8 KHN69619.1 - 0.32 10.3 2.5 0.6 9.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 KHN69619.1 - 0.65 10.3 7.0 0.81 10.0 5.3 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pyrophosphatase PF00719.19 KHN69621.1 - 1.3e-50 171.4 0.5 1.6e-50 171.0 0.5 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ras PF00071.22 KHN69622.1 - 1.1e-50 171.5 0.0 1.2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN69622.1 - 8.4e-26 90.6 0.0 1.3e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN69622.1 - 6.1e-10 38.8 0.0 7.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KHN69622.1 - 0.00025 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KHN69622.1 - 0.024 14.2 0.0 0.13 11.8 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 KHN69622.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF4602 PF15375.6 KHN69623.1 - 0.0078 16.5 4.0 0.0089 16.3 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) Cofilin_ADF PF00241.20 KHN69624.1 - 2.1e-14 53.4 0.1 2.7e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pox_MCEL PF03291.16 KHN69626.1 - 6.6e-55 186.5 4.2 1.9e-54 185.0 4.2 1.6 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KHN69626.1 - 1.8e-14 54.2 0.1 6.5e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KHN69626.1 - 2e-12 47.2 0.1 4.8e-12 45.9 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KHN69626.1 - 1.5e-11 44.9 0.2 5.3e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KHN69626.1 - 3.3e-11 43.7 0.0 6.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KHN69626.1 - 7.7e-10 38.9 0.0 1.9e-09 37.6 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KHN69626.1 - 3.3e-05 23.3 0.2 4.5e-05 22.9 0.2 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KHN69626.1 - 0.00037 19.8 0.0 0.002 17.3 0.0 1.9 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family CMAS PF02353.20 KHN69626.1 - 0.0013 18.1 0.1 0.0022 17.4 0.1 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KHN69626.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CobU PF02283.16 KHN69626.1 - 0.014 14.9 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MetW PF07021.12 KHN69626.1 - 0.023 14.3 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KHN69626.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KHN69626.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Reovirus_L2 PF06016.11 KHN69626.1 - 0.24 8.6 0.0 0.3 8.3 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Sec5 PF15469.6 KHN69627.1 - 7.2e-10 39.0 5.0 7.2e-10 39.0 5.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 ATP-synt_F PF01990.17 KHN69627.1 - 0.45 10.9 6.8 2.4 8.5 0.5 3.5 5 0 0 5 5 5 0 ATP synthase (F/14-kDa) subunit DUF2433 PF10360.9 KHN69627.1 - 1.6 8.8 6.0 0.78 9.8 1.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2433) DUF1788 PF08747.11 KHN69627.1 - 1.9 8.5 5.4 1.7 8.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1788) K-box PF01486.17 KHN69627.1 - 2.2 8.5 7.8 45 4.3 0.4 4.2 4 0 0 4 4 4 0 K-box region Ribosom_S12_S23 PF00164.25 KHN69628.1 - 2.1e-39 133.6 0.7 2.8e-39 133.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 VWA_2 PF13519.6 KHN69629.1 - 9.6e-07 29.4 0.1 1.6e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KHN69629.1 - 0.0018 18.1 0.2 0.0023 17.8 0.2 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KHN69629.1 - 0.0063 16.3 0.6 0.014 15.3 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif TLC PF03219.14 KHN69630.1 - 2.1e-40 138.9 27.9 2.6e-40 138.6 27.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter YdaS_antitoxin PF15943.5 KHN69631.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT RNA_pol_3_Rpc31 PF11705.8 KHN69631.1 - 2.6 8.3 14.0 10 6.3 14.0 1.7 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DEAD PF00270.29 KHN69632.1 - 5.3e-46 156.6 0.0 9.6e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69632.1 - 7.9e-28 97.0 0.0 5.9e-27 94.2 0.0 2.4 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69632.1 - 4.5e-06 26.8 0.0 8.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KHN69632.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KHN69632.1 - 0.005 16.1 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase MS_channel PF00924.18 KHN69633.1 - 1.8e-18 66.8 1.7 3.8e-18 65.8 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel HIT PF01230.23 KHN69634.1 - 1.4e-17 64.2 0.1 2.3e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KHN69634.1 - 2.9e-05 24.5 0.3 5.1e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding phiKZ_IP PF12699.7 KHN69634.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins HECT_2 PF09814.9 KHN69635.1 - 0.00015 20.8 1.1 0.00023 20.1 0.6 1.6 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PNMA PF14893.6 KHN69636.1 - 0.024 14.1 0.1 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 PNMA TLC PF03219.14 KHN69637.1 - 3.3e-38 131.7 28.2 4e-38 131.4 28.2 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter COX2 PF00116.20 KHN69637.1 - 0.0087 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Sen15 PF09631.10 KHN69637.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Sen15 protein UDG PF03167.19 KHN69638.1 - 2.6e-24 86.0 0.0 4.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Nfu_N PF08712.11 KHN69638.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Vhr1 PF04001.13 KHN69638.1 - 0.084 13.2 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Transcription factor Vhr1 TLC PF03219.14 KHN69639.1 - 6.1e-51 173.7 29.6 7e-51 173.5 29.6 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Proteasome PF00227.26 KHN69640.1 - 8.5e-33 113.4 0.1 9.9e-33 113.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KHN69640.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature adh_short PF00106.25 KHN69641.1 - 1.7e-17 63.5 0.1 3e-09 36.6 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KHN69641.1 - 3.3e-06 26.8 0.1 0.00028 20.5 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KHN69641.1 - 3.2e-05 23.9 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KHN69641.1 - 0.033 13.7 0.1 0.35 10.3 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KHN69641.1 - 0.035 14.0 0.0 0.047 13.6 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding Pkinase PF00069.25 KHN69642.1 - 6.2e-26 91.3 0.0 1e-25 90.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69642.1 - 7.4e-09 35.3 0.1 1.1e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN69642.1 - 0.00074 18.9 0.1 0.046 13.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like NIF PF03031.18 KHN69643.1 - 3.6e-09 36.6 0.1 5.5e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PI3_PI4_kinase PF00454.27 KHN69644.1 - 1.5e-17 64.3 0.2 1.1e-13 51.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DCX PF03607.17 KHN69644.1 - 0.04 14.0 0.1 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Doublecortin Rep_fac-A_C PF08646.10 KHN69645.1 - 4.8e-54 182.1 4.1 1.8e-52 177.0 2.2 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KHN69645.1 - 5.1e-22 77.6 0.7 1.5e-21 76.1 0.7 1.9 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 KHN69645.1 - 2.4e-13 49.8 4.8 2.4e-10 40.3 0.2 4.2 5 0 0 5 5 5 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 KHN69645.1 - 3.1e-11 43.2 0.1 9.6e-10 38.4 0.0 2.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 KHN69645.1 - 3.5e-06 26.9 1.8 0.0012 18.6 0.7 3.1 2 1 0 2 2 2 2 Cell division control protein 24, OB domain 3 Izumo-Ig PF16706.5 KHN69645.1 - 0.068 13.2 0.8 11 6.1 0.0 2.9 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain DNA_pol_B_3 PF08408.10 KHN69645.1 - 0.086 13.0 2.3 9.4 6.5 0.2 2.8 3 0 0 3 3 3 0 DNA polymerase family B viral insert RMI1_C PF16099.5 KHN69645.1 - 0.12 12.2 0.2 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Recq-mediated genome instability protein 1, C-terminal OB-fold PRP38 PF03371.15 KHN69646.1 - 6.5e-19 68.4 0.3 7.4e-19 68.3 0.3 1.0 1 0 0 1 1 1 1 PRP38 family Ehbp PF10622.9 KHN69646.1 - 0.076 13.1 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) IBN_N PF03810.19 KHN69647.1 - 0.0062 16.4 0.1 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cpn60_TCP1 PF00118.24 KHN69648.1 - 1.7e-137 459.1 0.2 1.9e-137 458.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family V_ATPase_prox PF18274.1 KHN69648.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe AAA_6 PF12774.7 KHN69649.1 - 2.3e-36 125.4 1.4 5.7e-23 81.4 0.7 3.1 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KHN69649.1 - 2.1e-13 50.2 8.5 2.1e-13 50.2 8.5 3.8 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 KHN69649.1 - 9.3e-13 48.4 0.0 0.00018 21.5 0.0 5.4 5 0 0 5 5 5 2 AAA domain (dynein-related subfamily) MT PF12777.7 KHN69649.1 - 3.1e-08 33.0 6.1 6.6e-08 31.9 6.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 KHN69649.1 - 2.5e-06 27.8 0.2 0.061 13.6 0.2 4.3 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KHN69649.1 - 2.6e-05 24.7 0.4 0.78 10.2 0.0 5.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KHN69649.1 - 7.1e-05 22.4 0.0 2.4 7.6 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_16 PF13191.6 KHN69649.1 - 0.00044 20.7 0.0 11 6.4 0.0 4.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 KHN69649.1 - 0.0094 15.7 0.1 5 6.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain Laminin_II PF06009.12 KHN69649.1 - 0.015 15.3 2.4 0.054 13.5 2.4 1.9 1 0 0 1 1 1 0 Laminin Domain II RNA_helicase PF00910.22 KHN69649.1 - 0.036 14.5 2.5 8.9 6.8 0.1 3.9 4 0 0 4 4 3 0 RNA helicase Med4 PF10018.9 KHN69649.1 - 0.11 12.1 1.5 0.27 10.9 1.5 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RsgA_GTPase PF03193.16 KHN69649.1 - 0.17 11.8 0.5 25 4.7 0.0 3.9 4 0 0 4 4 4 0 RsgA GTPase NPV_P10 PF05531.12 KHN69649.1 - 0.43 11.1 1.3 4.2 7.9 1.3 2.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Laminin_I PF06008.14 KHN69649.1 - 0.46 10.2 5.8 6.6 6.4 1.8 2.5 2 0 0 2 2 2 0 Laminin Domain I HATPase_c_5 PF14501.6 KHN69649.1 - 1.2 9.1 6.7 1.2 9.0 0.2 4.2 5 0 0 5 5 4 0 GHKL domain DUF3450 PF11932.8 KHN69649.1 - 1.3 8.3 3.9 3.9 6.7 3.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_14 PF13173.6 KHN69649.1 - 1.6 8.8 8.6 8.5 6.4 0.0 4.9 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 KHN69649.1 - 3.8 8.0 6.1 73 3.9 0.1 4.8 5 0 0 5 5 5 0 ABC transporter BRE1 PF08647.11 KHN69649.1 - 6.2 7.0 13.4 0.24 11.5 4.7 3.5 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase VWD PF00094.25 KHN69650.1 - 0.016 15.5 1.0 0.031 14.5 0.6 1.7 1 1 0 1 1 1 0 von Willebrand factor type D domain MOZ_SAS PF01853.18 KHN69651.1 - 1.9e-74 249.2 0.8 2.8e-74 248.6 0.8 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KHN69651.1 - 1.6e-20 72.5 1.9 3.4e-20 71.4 1.9 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KHN69651.1 - 4.7e-16 58.4 0.0 9.8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KHN69651.1 - 0.0032 17.8 0.0 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KHN69651.1 - 0.004 17.4 0.1 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family UPF0113_N PF17833.1 KHN69652.1 - 5.1e-22 78.2 0.5 9.4e-22 77.4 0.5 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KHN69652.1 - 2.8e-19 69.2 0.1 6.4e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain PUA PF01472.20 KHN69652.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 PUA domain Helicase_C PF00271.31 KHN69653.1 - 2.6e-13 50.3 1.4 4.6e-12 46.3 0.1 3.3 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.23 KHN69653.1 - 3.9e-11 43.2 0.0 1.3e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 KHN69653.1 - 2e-06 27.7 1.8 3.5e-06 26.9 0.5 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KHN69653.1 - 1.7e-05 25.1 0.0 8.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KHN69653.1 - 0.00015 22.0 0.0 0.00015 22.0 0.0 2.8 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KHN69653.1 - 0.0031 16.7 0.1 0.0065 15.7 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 KHN69653.1 - 0.0034 17.7 1.7 0.0062 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KHN69653.1 - 0.0045 17.0 0.1 0.012 15.6 0.1 1.7 1 1 0 1 1 1 1 Flavivirus DEAD domain DUF2969 PF11184.8 KHN69653.1 - 0.017 15.5 0.1 0.05 14.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) Viral_helicase1 PF01443.18 KHN69653.1 - 0.05 13.3 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KHN69653.1 - 0.99 9.4 0.0 0.99 9.4 0.0 3.9 4 1 1 5 5 5 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KHN69653.1 - 1.1 9.3 8.6 0.48 10.5 1.7 3.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 KHN69654.1 - 7.5e-40 136.5 0.1 1.8e-39 135.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69654.1 - 4.5e-24 84.9 0.0 5.7e-23 81.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KHN69654.1 - 4.6e-09 36.4 0.0 9.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KHN69654.1 - 1.7e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KHN69654.1 - 0.18 12.0 0.0 3.4 7.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KHN69654.1 - 0.41 10.4 2.1 0.5 10.1 0.0 2.2 4 0 0 4 4 4 0 AAA domain MutS_V PF00488.21 KHN69656.1 - 4e-64 216.1 0.3 1e-63 214.8 0.3 1.7 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 KHN69656.1 - 5.1e-34 116.9 0.1 1.3e-33 115.6 0.1 1.8 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 KHN69656.1 - 5.5e-28 98.5 0.4 1.4e-27 97.2 0.1 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KHN69656.1 - 8e-10 38.9 1.2 3.1e-09 37.1 1.2 2.1 1 0 0 1 1 1 1 MutS family domain IV Mre11_DNA_bind PF04152.14 KHN69656.1 - 0.0091 16.3 0.2 0.038 14.3 0.2 2.1 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Bac_DnaA PF00308.18 KHN69658.1 - 0.023 14.6 0.2 0.026 14.4 0.2 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein Peptidase_M24 PF00557.24 KHN69659.1 - 2.5e-31 109.0 0.0 3.1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3591 PF12157.8 KHN69661.1 - 4.3e-115 384.9 0.0 1.4e-114 383.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 KHN69661.1 - 4.6e-22 77.9 0.1 3.5e-21 75.0 0.1 2.4 2 0 0 2 2 2 1 Bromodomain zf-CCHC_6 PF15288.6 KHN69661.1 - 1e-06 28.5 2.6 2e-06 27.5 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KHN69661.1 - 0.1 12.7 2.8 0.081 13.0 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle DNA_pol3_delta2 PF13177.6 KHN69663.1 - 4.4e-08 33.1 0.1 1.4e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.18 KHN69663.1 - 0.0012 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.6 KHN69663.1 - 0.0051 17.3 0.0 0.013 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain Rep_fac_C PF08542.11 KHN69663.1 - 0.023 15.1 0.5 0.057 13.8 0.2 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain AAA_22 PF13401.6 KHN69663.1 - 0.039 14.2 0.2 0.62 10.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 KHN69663.1 - 0.099 12.6 0.0 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KHN69663.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain Ada3 PF10198.9 KHN69664.1 - 4.4e-05 23.6 1.1 4.4e-05 23.6 1.1 1.6 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 tRNA-synt_His PF13393.6 KHN69664.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase PhetRS_B1 PF18262.1 KHN69664.1 - 0.53 10.5 3.7 0.83 9.9 0.2 2.5 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain Methyltransf_8 PF05148.15 KHN69665.1 - 4.4e-79 265.4 0.7 5e-79 265.2 0.7 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KHN69665.1 - 2.4e-09 37.7 0.1 1.2e-07 32.3 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KHN69665.1 - 1.9e-06 28.5 0.1 0.00051 20.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KHN69665.1 - 2e-05 24.4 0.2 0.025 14.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KHN69665.1 - 0.029 13.7 0.1 0.25 10.6 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Peptidase_C39 PF03412.15 KHN69665.1 - 0.14 12.0 0.1 0.61 9.9 0.1 2.1 1 1 0 1 1 1 0 Peptidase C39 family FeoB_associated PF12669.7 KHN69666.1 - 0.097 13.1 0.4 0.097 13.1 0.4 2.7 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Ndc80_HEC PF03801.13 KHN69667.1 - 1.1e-38 132.3 0.0 2.3e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Bin3 PF06859.12 KHN69667.1 - 3.9 8.2 5.8 2 9.1 1.2 2.6 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Fibrillarin PF01269.17 KHN69668.1 - 2.9e-101 337.3 0.0 3.4e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KHN69668.1 - 0.025 14.3 0.0 0.025 14.3 0.0 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Ribosomal_L28e PF01778.17 KHN69669.1 - 1.4e-29 103.2 0.0 1.4e-29 103.2 0.0 2.2 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 KHN69669.1 - 1.7e-06 28.5 8.2 1.7e-06 28.5 8.2 1.7 2 0 0 2 2 2 1 Mak16 protein C-terminal region Med31 PF05669.12 KHN69669.1 - 0.019 14.9 0.4 0.036 14.1 0.4 1.6 1 1 0 1 1 1 0 SOH1 MtlR PF05068.12 KHN69669.1 - 0.057 13.4 1.0 0.097 12.7 1.0 1.3 1 0 0 1 1 1 0 Mannitol repressor Latrophilin PF02354.16 KHN69669.1 - 0.62 9.1 2.8 0.84 8.6 2.8 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region LUC7 PF03194.15 KHN69670.1 - 1.6e-28 100.1 7.3 3e-28 99.2 7.3 1.4 1 1 0 1 1 1 1 LUC7 N_terminus Pentapeptide_4 PF13599.6 KHN69671.1 - 0.035 14.3 0.1 3.9 7.7 0.0 3.2 2 1 1 3 3 3 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 KHN69671.1 - 0.11 12.6 0.2 0.9 9.7 0.0 2.6 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Got1 PF04178.12 KHN69672.1 - 0.012 16.0 12.7 0.015 15.7 12.7 1.2 1 0 0 1 1 1 0 Got1/Sft2-like family SieB PF14163.6 KHN69672.1 - 0.2 11.1 1.6 0.31 10.5 1.6 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B Herpes_LMP1 PF05297.11 KHN69672.1 - 1.9 7.6 8.1 2 7.6 8.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF202 PF02656.15 KHN69672.1 - 4.6 7.8 12.0 70 4.0 12.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF373 PF04123.13 KHN69672.1 - 5.6 6.3 11.7 2.2 7.7 4.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF872 PF05915.12 KHN69672.1 - 7 6.9 10.7 0.57 10.4 4.6 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DAO PF01266.24 KHN69673.1 - 4.1e-38 131.9 0.0 5.5e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KHN69673.1 - 8.7e-25 87.0 0.1 1.7e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KHN69673.1 - 1.6e-07 30.8 3.8 0.00017 20.8 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KHN69673.1 - 0.00031 20.2 1.2 0.00031 20.2 1.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KHN69673.1 - 0.00047 19.5 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KHN69673.1 - 0.0022 16.8 0.4 0.0033 16.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KHN69673.1 - 0.0064 17.0 0.4 0.018 15.6 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KHN69673.1 - 0.0093 16.2 0.8 0.039 14.2 0.8 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KHN69673.1 - 0.011 14.9 0.3 0.011 14.9 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 KHN69673.1 - 0.016 14.4 1.2 0.02 14.2 0.1 1.6 2 0 0 2 2 2 0 Thi4 family L27_1 PF09058.10 KHN69673.1 - 0.19 11.7 0.2 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 L27_1 RabGAP-TBC PF00566.18 KHN69674.1 - 5.3e-06 26.2 3.0 0.00011 22.0 3.0 2.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Methyltransf_12 PF08242.12 KHN69674.1 - 0.042 14.6 0.6 0.25 12.1 0.1 2.4 3 0 0 3 3 3 0 Methyltransferase domain TAT_signal PF10518.9 KHN69674.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Beta-Casp PF10996.8 KHN69675.1 - 3.4e-31 107.8 0.0 7.6e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KHN69675.1 - 7.3e-22 77.7 0.1 1.8e-21 76.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KHN69675.1 - 1.2e-17 64.6 0.0 2.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KHN69675.1 - 2.5e-16 59.3 0.0 2e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KHN69675.1 - 8.5e-11 41.7 0.1 4.5e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KHN69675.1 - 6.7e-07 28.8 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family CPSF73-100_C PF11718.8 KHN69675.1 - 8.5e-06 25.5 0.1 2.4e-05 24.0 0.1 1.7 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_3 PF13483.6 KHN69675.1 - 0.00011 22.1 0.0 0.00036 20.4 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 KHN69676.1 - 3.9e-86 289.3 0.0 5e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribonuc_red_lgC PF02867.15 KHN69677.1 - 9.5e-180 598.6 0.0 1.4e-179 598.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KHN69677.1 - 4.3e-20 71.5 0.1 1.3e-19 70.0 0.1 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain IL4 PF00727.18 KHN69677.1 - 0.084 13.1 2.2 0.32 11.2 0.1 2.8 3 1 0 3 3 3 0 Interleukin 4 UQ_con PF00179.26 KHN69678.1 - 6.1e-47 158.8 0.0 7e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KHN69678.1 - 1.8e-07 30.9 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KHN69678.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain SLD5_C PF16922.5 KHN69679.1 - 0.028 14.6 0.1 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus DUF295 PF03478.18 KHN69679.1 - 0.11 12.1 0.1 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF295) AAA_18 PF13238.6 KHN69680.1 - 2.1e-25 89.7 0.0 2.8e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KHN69680.1 - 8.1e-09 36.0 0.0 2.1e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KHN69680.1 - 6.6e-05 22.9 0.1 0.00019 21.4 0.1 1.8 2 0 0 2 2 2 1 NTPase SKI PF01202.22 KHN69680.1 - 0.00044 20.4 0.1 0.00077 19.6 0.1 1.6 1 1 0 1 1 1 1 Shikimate kinase ADK PF00406.22 KHN69680.1 - 0.00046 20.3 0.0 0.0092 16.1 0.0 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA PF00004.29 KHN69680.1 - 0.001 19.5 0.0 0.002 18.6 0.0 1.5 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) GvpD PF07088.11 KHN69680.1 - 0.0015 17.2 0.2 0.0018 16.9 0.2 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_33 PF13671.6 KHN69680.1 - 0.0017 18.6 0.0 0.0037 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KHN69680.1 - 0.002 18.0 0.9 0.0033 17.3 0.5 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein dNK PF01712.19 KHN69680.1 - 0.0024 17.8 0.6 0.35 10.7 0.1 2.4 1 1 1 2 2 2 1 Deoxynucleoside kinase RNA_helicase PF00910.22 KHN69680.1 - 0.0027 18.1 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 KHN69680.1 - 0.0035 17.1 0.5 0.0068 16.1 0.4 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KHN69680.1 - 0.0054 16.5 0.0 0.081 12.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KHN69680.1 - 0.013 15.8 0.4 0.024 14.9 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN69680.1 - 0.017 15.4 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KHN69680.1 - 0.019 14.6 0.0 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 KHN69680.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 KHN69680.1 - 0.041 13.3 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 KHN69680.1 - 0.092 13.1 0.1 0.15 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KHN69680.1 - 0.1 11.9 2.3 0.16 11.3 0.3 2.0 2 1 0 2 2 2 0 KaiC TsaE PF02367.17 KHN69680.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 KHN69680.1 - 0.17 10.9 0.2 0.28 10.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 KHN69680.1 - 0.17 11.6 0.2 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TEX13 PF15186.6 KHN69682.1 - 0.079 12.6 1.1 1 9.0 0.2 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family vATP-synt_E PF01991.18 KHN69682.1 - 0.31 10.4 5.6 0.61 9.5 5.6 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Topo_Zn_Ribbon PF08272.11 KHN69682.1 - 0.42 10.3 3.7 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Ribosomal_L27A PF00828.19 KHN69683.1 - 1.6e-14 54.6 0.0 2.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Kinesin PF00225.23 KHN69684.1 - 3.7e-68 229.9 0.5 7e-68 229.0 0.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KHN69684.1 - 1.8e-10 41.0 0.1 9.9e-10 38.5 0.2 2.1 1 1 0 1 1 1 1 Microtubule binding Caps_synth_GfcC PF06251.11 KHN69685.1 - 0.12 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC LPD25 PF18840.1 KHN69685.1 - 0.13 12.9 0.2 0.22 12.1 0.2 1.3 1 1 0 1 1 1 0 Large polyvalent protein associated domain 25 FYRN PF05964.14 KHN69686.1 - 4.9e-10 39.1 0.4 8.4e-10 38.3 0.4 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus CLASP_N PF12348.8 KHN69687.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal CCDC74_C PF14917.6 KHN69687.1 - 0.025 15.1 1.0 0.068 13.7 1.0 1.7 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal ATP-synt_ab PF00006.25 KHN69688.1 - 2.6e-66 223.3 0.0 3.6e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KHN69688.1 - 5.1e-12 46.1 1.6 1.1e-11 45.1 1.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 KHN69688.1 - 0.0048 15.9 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DNA_RNApol_7kD PF03604.13 KHN69689.1 - 5.3e-10 38.8 5.1 6.6e-10 38.5 5.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_SprT PF17283.2 KHN69689.1 - 0.0014 18.5 2.7 0.84 9.6 0.5 2.1 2 0 0 2 2 2 2 SprT-like zinc ribbon domain NOB1_Zn_bind PF08772.11 KHN69689.1 - 0.0028 17.8 0.6 0.0032 17.6 0.6 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like MCM_OB PF17207.3 KHN69689.1 - 0.0037 17.1 0.7 0.0037 17.1 0.7 1.1 1 0 0 1 1 1 1 MCM OB domain NCD3G PF07562.14 KHN69689.1 - 0.022 14.7 0.4 0.026 14.5 0.4 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR T4_baseplate PF12322.8 KHN69689.1 - 0.027 13.9 0.4 0.027 13.9 0.4 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Zn-ribbon_8 PF09723.10 KHN69689.1 - 0.068 13.3 1.0 0.12 12.5 0.9 1.5 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2HE PF16278.5 KHN69689.1 - 0.23 11.9 1.2 0.38 11.2 1.2 1.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Metalloenzyme PF01676.18 KHN69691.1 - 1.5e-62 211.2 0.5 1.7e-62 211.0 0.5 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 KHN69691.1 - 1.9e-51 174.6 1.5 3.1e-51 173.9 1.5 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.23 KHN69691.1 - 5.3e-06 26.0 0.0 1.8e-05 24.3 0.0 1.6 1 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KHN69691.1 - 1.9e-05 24.5 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PuR_N PF09182.10 KHN69691.1 - 0.086 12.8 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal PglZ PF08665.12 KHN69691.1 - 0.13 12.4 0.1 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 PglZ domain Ribosomal_60s PF00428.19 KHN69692.1 - 1.9e-07 31.6 4.2 2.4e-07 31.2 4.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DNA_pol_E_B PF04042.16 KHN69693.1 - 2.8e-20 72.6 0.0 5.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CDC48_N PF02359.18 KHN69693.1 - 0.058 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain PHD PF00628.29 KHN69694.1 - 1.2e-05 25.1 9.5 3.5e-05 23.6 9.5 1.8 1 0 0 1 1 1 1 PHD-finger RNase_PH PF01138.21 KHN69694.1 - 0.038 14.5 0.0 0.056 14.0 0.0 1.4 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 AGOG PF09171.10 KHN69694.1 - 0.055 12.8 0.2 0.08 12.2 0.2 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase PRANC PF09372.10 KHN69694.1 - 0.055 13.8 0.3 0.12 12.7 0.3 1.5 1 0 0 1 1 1 0 PRANC domain CorA PF01544.18 KHN69694.1 - 0.28 10.5 0.4 0.35 10.1 0.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DnaJ PF00226.31 KHN69695.1 - 6.4e-20 71.1 0.3 2.2e-19 69.3 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain MSC PF09402.10 KHN69695.1 - 0.04 13.4 0.3 0.049 13.1 0.3 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF3364 PF11844.8 KHN69695.1 - 0.2 11.9 2.7 0.19 12.0 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) Plk4_PB2 PF18409.1 KHN69695.1 - 0.37 11.5 6.0 1.8 9.3 0.3 2.4 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 RRM_1 PF00076.22 KHN69696.1 - 3.7e-56 186.8 9.5 3.3e-16 58.9 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KHN69696.1 - 4.4e-06 26.6 0.5 0.099 12.7 0.1 3.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KHN69696.1 - 2.2e-05 24.0 1.4 0.0015 18.1 0.0 3.2 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ureidogly_lyase PF04115.12 KHN69696.1 - 0.0054 16.5 0.1 0.01 15.6 0.1 1.4 1 0 0 1 1 1 1 Ureidoglycolate lyase RRM_3 PF08777.11 KHN69696.1 - 0.01 15.9 6.1 0.01 15.8 0.1 3.4 4 1 0 4 4 4 0 RNA binding motif RL PF17797.1 KHN69696.1 - 0.01 15.7 0.1 0.61 10.1 0.0 3.1 3 0 0 3 3 3 0 RL domain TbpB_C PF17483.2 KHN69696.1 - 0.02 15.2 1.2 0.12 12.7 0.2 2.6 2 2 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B NOP5NT PF08156.13 KHN69696.1 - 0.025 15.0 4.0 2.9 8.3 0.2 2.9 2 0 0 2 2 2 0 NOP5NT (NUC127) domain Fungal_TACC PF12709.7 KHN69696.1 - 0.034 14.6 0.2 0.12 12.8 0.2 2.0 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins RRM_2 PF04059.12 KHN69696.1 - 0.13 12.5 0.8 15 5.9 0.1 2.9 2 0 0 2 2 2 0 RNA recognition motif 2 PHM7_cyt PF14703.6 KHN69696.1 - 0.36 11.0 3.2 9.5 6.4 0.1 4.0 2 2 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter TAF PF02969.17 KHN69697.1 - 2.1e-19 69.5 0.0 5.2e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 KHN69697.1 - 1e-16 61.0 0.0 2.2e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain CBFD_NFYB_HMF PF00808.23 KHN69697.1 - 0.063 13.6 0.2 1.5 9.2 0.0 2.9 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NopRA1 PF16201.5 KHN69697.1 - 0.12 12.0 0.6 10 5.6 0.1 2.3 1 1 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 ORC2 PF04084.14 KHN69698.1 - 6.4e-16 58.2 3.3 1.5e-08 34.0 0.2 3.1 1 1 1 2 2 2 2 Origin recognition complex subunit 2 DUF4116 PF13475.6 KHN69698.1 - 0.027 14.2 1.1 0.36 10.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Sec7 PF01369.20 KHN69699.1 - 1.4e-30 106.3 1.8 1.4e-30 106.3 1.8 2.1 2 0 0 2 2 2 1 Sec7 domain RhoGEF PF00621.20 KHN69700.1 - 4.3e-06 27.1 2.0 1.1e-05 25.7 0.2 2.5 3 0 0 3 3 3 1 RhoGEF domain DUF4867 PF16161.5 KHN69700.1 - 0.0059 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4867) RIFIN PF02009.16 KHN69701.1 - 0.021 14.7 1.8 0.022 14.6 1.8 1.0 1 0 0 1 1 1 0 Rifin Caskin-tail PF16632.5 KHN69701.1 - 0.057 13.8 0.2 0.071 13.5 0.2 1.2 1 0 0 1 1 1 0 C-terminal region of Caskin Trp_leader2 PF08056.11 KHN69701.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan operon leader peptide TIR-like PF10137.9 KHN69701.1 - 0.083 12.9 0.6 0.092 12.7 0.6 1.1 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain PC_rep PF01851.22 KHN69702.1 - 0.0073 16.7 1.9 0.023 15.1 0.5 2.5 2 0 0 2 2 2 1 Proteasome/cyclosome repeat XPA_C PF05181.12 KHN69703.1 - 7.7e-18 64.2 0.6 1.4e-17 63.4 0.6 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 KHN69703.1 - 0.0016 18.5 0.1 0.003 17.5 0.1 1.4 1 0 0 1 1 1 1 XPA protein N-terminal UFD1 PF03152.14 KHN69704.1 - 5.3e-44 149.7 0.0 6.7e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Curto_V2 PF07325.11 KHN69705.1 - 0.94 9.4 6.1 0.21 11.5 0.2 2.7 3 0 0 3 3 3 0 Curtovirus V2 protein CK_II_beta PF01214.18 KHN69706.1 - 8.3e-50 169.1 0.1 1.4e-49 168.3 0.1 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DNA_pol_B_exo1 PF03104.19 KHN69707.1 - 1.5e-41 142.7 1.1 5.3e-41 140.9 1.1 2.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KHN69707.1 - 7.2e-13 48.1 8.6 5.3e-10 38.6 3.8 4.3 3 1 0 3 3 3 2 DNA polymerase family B DUF1744 PF08490.12 KHN69707.1 - 1.1e-12 47.2 0.1 2.2e-11 42.9 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1744) RNase_H_2 PF13482.6 KHN69707.1 - 1.9e-07 31.2 0.1 1.7e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KHN69707.1 - 1.8e-06 27.8 2.2 1.2e-05 25.1 0.3 2.9 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB EcpB_C PF18649.1 KHN69707.1 - 0.099 12.6 0.1 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 EcpB C-terminal domain IBN_N PF03810.19 KHN69709.1 - 0.00046 20.0 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 KHN69709.1 - 0.0047 17.4 0.0 5.4 7.6 0.0 4.8 4 1 0 5 5 5 1 HEAT-like repeat PTEN_C2 PF10409.9 KHN69710.1 - 4.1e-07 29.8 2.6 7e-07 29.1 0.0 2.6 3 0 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein FH2 PF02181.23 KHN69710.1 - 1.5e-06 27.6 3.5 2.6e-06 26.8 3.5 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain Acyltransferase PF01553.21 KHN69711.1 - 1.3e-20 73.4 0.0 2.1e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KHN69711.1 - 0.00097 19.2 0.2 0.0022 18.0 0.2 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Metallophos PF00149.28 KHN69712.1 - 1e-29 104.5 0.9 1.4e-29 104.0 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FeS_assembly_P PF01883.19 KHN69713.1 - 1.2e-05 25.3 0.2 0.021 15.0 0.0 2.6 3 0 0 3 3 3 2 Iron-sulfur cluster assembly protein DUF1641 PF07849.11 KHN69713.1 - 0.13 12.2 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Ribosomal_L44 PF00935.19 KHN69714.1 - 3.1e-28 98.1 6.1 3.1e-28 98.1 6.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L44 DUF866 PF05907.13 KHN69714.1 - 0.078 12.9 0.8 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) HNH_5 PF14279.6 KHN69714.1 - 0.11 12.4 0.6 0.11 12.4 0.6 2.2 2 1 1 3 3 3 0 HNH endonuclease Rpr2 PF04032.16 KHN69714.1 - 0.96 9.8 6.6 1.7 9.0 6.6 1.4 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain UQ_con PF00179.26 KHN69715.1 - 6.3e-46 155.5 0.0 7.5e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KHN69715.1 - 0.0008 19.1 0.0 0.00096 18.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KHN69715.1 - 0.077 13.3 0.2 0.16 12.3 0.2 1.5 1 1 0 1 1 1 0 RWD domain SNF2_N PF00176.23 KHN69716.1 - 2e-62 210.9 1.0 4.1e-62 209.9 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KHN69716.1 - 3e-21 75.8 0.3 2.5e-19 69.7 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69716.1 - 4.3e-15 56.1 0.0 1.3e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN69716.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SLIDE PF09111.10 KHN69716.1 - 4.2e-08 33.2 5.0 4.2e-08 33.2 5.0 3.1 2 1 0 2 2 2 1 SLIDE SWI2_SNF2 PF18766.1 KHN69716.1 - 3e-07 30.3 0.0 7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HAND PF09110.11 KHN69716.1 - 8.4e-06 26.5 2.0 8.4e-06 26.5 2.0 3.0 3 1 1 4 4 4 1 HAND HDA2-3 PF11496.8 KHN69716.1 - 1e-05 24.9 0.1 8.4e-05 21.9 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KHN69716.1 - 0.00066 19.0 0.1 0.002 17.4 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UCH PF00443.29 KHN69717.1 - 2.7e-40 138.5 3.5 5.6e-40 137.5 3.5 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KHN69717.1 - 7.4e-17 61.9 0.6 7.2e-12 45.5 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase 7TMR-DISM_7TM PF07695.11 KHN69717.1 - 0.11 12.4 6.8 0.24 11.2 6.8 1.6 1 0 0 1 1 1 0 7TM diverse intracellular signalling TctB PF07331.11 KHN69717.1 - 0.86 9.9 5.8 1.8 8.8 0.1 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1218 PF06749.12 KHN69717.1 - 9.7 6.8 10.1 10 6.7 2.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF1430 PF07242.11 KHN69718.1 - 0.028 14.7 7.1 1.9 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Pex24p PF06398.11 KHN69718.1 - 0.047 12.7 0.1 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin AgrB PF04647.15 KHN69718.1 - 0.14 11.5 7.0 0.22 10.8 7.0 1.4 1 1 0 1 1 1 0 Accessory gene regulator B DUF5592 PF17332.2 KHN69718.1 - 0.14 12.7 5.4 0.23 12.0 3.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5592) Trp_oprn_chp PF09534.10 KHN69718.1 - 0.18 11.6 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SPC12 PF06645.13 KHN69718.1 - 7.6 6.7 9.4 22 5.2 4.6 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Adaptin_binding PF10199.9 KHN69720.1 - 0.023 15.3 0.9 0.023 15.3 0.9 2.0 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CorA PF01544.18 KHN69720.1 - 2.5 7.3 6.7 0.35 10.1 1.5 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2935 PF11155.8 KHN69721.1 - 0.0075 16.6 0.2 0.0075 16.6 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF2935) Orf78 PF06024.12 KHN69722.1 - 0.064 13.6 8.5 0.97 9.8 2.9 3.3 3 0 0 3 3 3 0 Orf78 (ac78) L6_membrane PF05805.12 KHN69722.1 - 0.088 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 L6 membrane protein Connexin PF00029.19 KHN69722.1 - 0.41 10.4 5.4 8.2 6.1 0.2 2.3 2 0 0 2 2 2 0 Connexin AAA_assoc_C PF09821.9 KHN69722.1 - 1.7 9.2 9.2 2.4 8.7 1.0 2.8 2 0 0 2 2 2 0 C-terminal AAA-associated domain Tau95_N PF17682.1 KHN69722.1 - 3.7 7.8 7.1 20 5.4 3.2 2.6 2 0 0 2 2 2 0 Tau95 Triple barrel domain Rad10 PF03834.14 KHN69724.1 - 5e-31 107.1 0.0 1.3e-30 105.8 0.0 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KHN69724.1 - 1.9e-05 25.1 0.1 3.9e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KHN69724.1 - 0.038 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 KHN69724.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain HHH PF00633.23 KHN69724.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3701 PF12482.8 KHN69724.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Phage integrase protein YugN PF08868.10 KHN69724.1 - 0.13 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 YugN-like family ECR1_N PF14382.6 KHN69725.1 - 7.3e-08 32.1 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KHN69725.1 - 2e-06 28.0 0.1 4.3e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 KHN69725.1 - 0.0066 17.0 0.9 0.079 13.6 0.1 2.3 1 1 1 2 2 2 1 Exosome component EXOSC1/CSL4 Beta-Casp PF10996.8 KHN69726.1 - 2.1e-25 89.1 0.0 4.3e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KHN69726.1 - 2.2e-21 76.2 0.0 3.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KHN69726.1 - 2.3e-15 56.3 0.0 5.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 KHN69726.1 - 8.4e-15 55.3 0.2 5.6e-14 52.6 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KHN69726.1 - 5.4e-09 35.8 0.1 3.4e-08 33.2 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KHN69726.1 - 0.00016 21.6 0.0 0.0005 20.0 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KHN69726.1 - 0.0002 20.7 0.0 0.00051 19.3 0.0 1.7 1 0 0 1 1 1 1 Putative beta-lactamase-like family MS_channel PF00924.18 KHN69727.1 - 4.9e-13 49.1 0.4 9.8e-13 48.1 0.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KHN69727.1 - 0.0047 16.4 1.3 0.012 15.2 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KHN69727.1 - 0.024 14.6 0.2 0.088 12.8 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain DUF761 PF05553.11 KHN69727.1 - 0.31 10.6 1.6 6.1 6.5 0.1 2.6 2 0 0 2 2 2 0 Cotton fibre expressed protein GWT1 PF06423.12 KHN69727.1 - 3.6 7.7 7.0 1.9 8.6 3.2 2.2 2 0 0 2 2 2 0 GWT1 PMT_4TMC PF16192.5 KHN69727.1 - 6.9 6.2 9.9 7.2 6.1 1.4 2.8 2 1 1 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase Exo_endo_phos PF03372.23 KHN69728.1 - 0.00048 19.7 0.0 0.00085 18.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KHN69728.1 - 0.0016 18.3 0.3 0.059 13.2 0.3 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase HECT PF00632.25 KHN69729.1 - 3.9e-85 286.0 0.4 8.8e-85 284.9 0.4 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 KHN69729.1 - 0.00025 20.1 1.0 0.00091 18.3 0.1 2.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF842 PF05811.13 KHN69729.1 - 0.63 9.7 11.0 0.3 10.8 7.5 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CABS1 PF15367.6 KHN69730.1 - 0.021 13.9 0.4 0.034 13.3 0.4 1.3 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 DUF3656 PF12392.8 KHN69730.1 - 0.073 13.7 0.2 0.39 11.4 0.1 2.3 2 0 0 2 2 2 0 Collagenase VCBS PF13517.6 KHN69731.1 - 0.0033 18.0 4.5 0.39 11.4 0.1 4.4 4 2 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MFS_1 PF07690.16 KHN69732.1 - 3.3e-20 72.3 23.5 3.3e-20 72.3 23.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 KHN69733.1 - 1.3e-41 142.1 0.1 3.6e-41 140.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KHN69733.1 - 2.9e-17 62.4 0.1 6.3e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KHN69733.1 - 6.3e-13 48.3 0.1 1.4e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KHN69733.1 - 1.1e-06 28.6 0.0 6.3e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KHN69733.1 - 4.8e-06 26.8 0.0 2e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KHN69733.1 - 7.6e-06 26.4 0.2 0.016 15.6 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KHN69733.1 - 1.2e-05 25.1 0.0 3.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KHN69733.1 - 0.0031 17.8 2.4 0.28 11.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KHN69733.1 - 0.012 15.0 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KHN69733.1 - 0.016 14.7 0.0 0.052 13.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KHN69733.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.16 KHN69733.1 - 0.017 14.6 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KHN69733.1 - 0.019 15.1 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KHN69733.1 - 0.027 14.5 0.0 0.079 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN69733.1 - 0.029 14.1 0.1 0.085 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KHN69733.1 - 0.029 14.7 0.0 0.084 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KHN69733.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 KHN69733.1 - 0.064 12.6 0.2 0.88 8.9 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 KHN69733.1 - 0.067 12.9 0.0 0.39 10.4 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_18 PF13238.6 KHN69733.1 - 0.11 13.0 0.0 0.63 10.6 0.0 2.4 3 1 0 3 3 3 0 AAA domain Bromodomain PF00439.25 KHN69734.1 - 2.6e-23 81.9 0.8 6.8e-23 80.5 0.8 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.7 KHN69734.1 - 0.00031 21.1 0.2 0.0011 19.3 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KHN69734.1 - 0.00032 20.6 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KHN69734.1 - 0.00094 19.4 0.2 0.0043 17.3 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family PAP2 PF01569.21 KHN69735.1 - 4.1e-25 88.1 4.3 7.1e-25 87.4 4.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KHN69735.1 - 0.0014 18.3 14.1 0.012 15.3 12.9 2.9 1 1 1 2 2 2 1 PAP2 superfamily DUF4131 PF13567.6 KHN69735.1 - 0.27 10.9 1.8 11 5.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MARVEL PF01284.23 KHN69735.1 - 0.37 10.8 8.9 1.9 8.5 0.7 2.3 2 0 0 2 2 2 0 Membrane-associating domain Phage_holin_3_6 PF07332.11 KHN69735.1 - 3.5 7.7 7.0 0.91 9.6 1.7 2.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Proteasome PF00227.26 KHN69736.1 - 1.5e-38 132.2 0.5 1.7e-38 132.0 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit tRNA-synt_1c PF00749.21 KHN69737.1 - 5.7e-94 314.5 0.9 2.4e-93 312.5 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KHN69737.1 - 2.9e-33 115.2 0.0 6.5e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 KHN69737.1 - 0.0072 16.4 0.7 0.016 15.2 0.7 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Linker_histone PF00538.19 KHN69737.1 - 0.12 12.7 0.4 0.33 11.3 0.4 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family KELK PF15796.5 KHN69738.1 - 0.0079 16.6 2.3 0.0085 16.5 2.3 1.2 1 0 0 1 1 1 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Peptidase_M16 PF00675.20 KHN69739.1 - 1.7e-33 115.7 0.0 5e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 KHN69739.1 - 6.9e-15 55.1 0.6 6.7e-13 48.6 0.1 2.7 2 1 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 KHN69739.1 - 1.9e-12 47.5 1.1 2.6e-07 30.9 0.1 3.0 2 2 0 2 2 2 2 Peptidase M16 inactive domain TetR_C_10 PF16295.5 KHN69739.1 - 0.081 13.2 0.4 0.37 11.1 0.4 2.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3829 PF12889.7 KHN69740.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Act-Frag_cataly PF09192.10 KHN69740.1 - 0.068 12.5 0.2 0.28 10.5 0.2 1.9 1 1 0 1 1 1 0 Actin-fragmin kinase, catalytic Homeobox_KN PF05920.11 KHN69741.1 - 2.4e-18 65.7 0.1 4.3e-18 64.9 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KHN69741.1 - 4e-05 23.4 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Sacchrp_dh_NADP PF03435.18 KHN69742.1 - 4.6e-10 39.8 0.5 1e-09 38.7 0.5 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain CLP1_P PF16575.5 KHN69742.1 - 0.0029 17.4 0.1 0.0048 16.7 0.1 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop zf-CCCH_4 PF18044.1 KHN69744.1 - 5e-08 32.6 1.3 5e-08 32.6 1.3 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KHN69744.1 - 6.7e-07 29.2 4.3 6.7e-07 29.2 4.3 3.1 2 1 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 KHN69744.1 - 3.3e-06 26.9 10.9 1.2e-05 25.1 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KHN69744.1 - 0.00018 21.7 5.5 0.00031 20.9 5.5 1.5 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 KHN69744.1 - 0.036 14.8 6.8 0.051 14.3 5.9 1.7 1 1 1 2 2 2 0 Torus domain DUF5463 PF17551.2 KHN69744.1 - 0.057 13.3 0.4 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5463) zf-CCCH_2 PF14608.6 KHN69744.1 - 0.11 13.0 18.3 1.3 9.6 5.6 3.0 2 2 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_L24e PF01246.20 KHN69745.1 - 9.6e-29 99.4 6.6 1.9e-28 98.5 6.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 KHN69745.1 - 0.00025 20.9 5.0 0.00025 20.9 5.0 1.9 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif SUIM_assoc PF16619.5 KHN69745.1 - 0.2 11.8 0.8 0.32 11.1 0.8 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ABC_tran PF00005.27 KHN69746.1 - 7.7e-24 84.8 0.3 2.1e-23 83.3 0.2 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KHN69746.1 - 5.3e-06 26.0 0.1 9.3e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KHN69746.1 - 0.0014 18.5 0.1 0.95 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KHN69746.1 - 0.0063 16.9 0.2 0.017 15.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KHN69746.1 - 0.012 15.3 0.6 0.025 14.3 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KHN69746.1 - 0.016 15.1 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KHN69746.1 - 0.025 15.1 0.1 0.055 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KHN69746.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KHN69746.1 - 0.086 12.8 0.1 0.71 9.8 0.0 2.1 1 1 0 2 2 2 0 NTPase AAA_22 PF13401.6 KHN69746.1 - 0.12 12.7 1.0 0.25 11.6 1.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KHN69746.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KHN69746.1 - 0.13 12.0 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain DUF5099 PF17025.5 KHN69747.1 - 1.4e-27 96.3 0.7 8e-26 90.6 0.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5099) UQ_con PF00179.26 KHN69748.1 - 6.4e-23 80.9 0.0 7.7e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S24e PF01282.19 KHN69750.1 - 4.6e-18 64.9 1.1 5.3e-18 64.7 0.3 1.6 1 1 0 1 1 1 1 Ribosomal protein S24e NodZ PF05830.11 KHN69750.1 - 0.041 12.7 0.2 0.047 12.5 0.2 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) DUF3991 PF13154.6 KHN69750.1 - 0.058 13.8 1.7 0.18 12.2 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3991) Stork_head PF10264.9 KHN69750.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Ribosomal_S30 PF04758.14 KHN69751.1 - 1.9e-16 60.0 2.0 2.2e-16 59.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 LSM PF01423.22 KHN69752.1 - 1e-15 57.1 0.6 1.6e-15 56.5 0.6 1.3 1 0 0 1 1 1 1 LSM domain RNase_H2_suC PF08615.11 KHN69752.1 - 0.019 15.1 0.1 0.021 15.0 0.1 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CTP_transf_like PF01467.26 KHN69753.1 - 5.1e-25 88.3 0.1 1.5e-24 86.8 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF5639 PF18690.1 KHN69753.1 - 0.099 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) Mnd1 PF03962.15 KHN69754.1 - 4e-22 78.2 0.5 4e-22 78.2 0.5 2.2 2 1 1 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 KHN69754.1 - 3.1e-12 46.4 4.7 1.9e-11 43.9 0.5 3.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain HAUS5 PF14817.6 KHN69754.1 - 0.0017 17.2 3.4 0.0024 16.7 3.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 Sec34 PF04136.15 KHN69754.1 - 0.0036 17.2 2.1 0.0036 17.2 2.1 1.6 2 0 0 2 2 2 1 Sec34-like family TrmB PF01978.19 KHN69754.1 - 0.015 15.2 0.0 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.16 KHN69754.1 - 0.015 15.7 0.2 0.16 12.3 0.1 2.2 2 1 0 2 2 2 0 Penicillinase repressor RQC PF09382.10 KHN69754.1 - 0.03 14.1 0.1 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 RQC domain HAP1_N PF04849.13 KHN69754.1 - 0.034 13.3 10.5 0.057 12.6 10.5 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1474 PF07342.11 KHN69754.1 - 0.11 13.0 4.0 0.16 12.5 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1474) Wtap PF17098.5 KHN69754.1 - 0.13 12.2 4.8 0.2 11.6 4.8 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family BPS1 PF05633.11 KHN69754.1 - 0.19 10.7 3.8 0.25 10.3 3.8 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related ArgoMid PF16487.5 KHN69754.1 - 0.21 11.8 2.2 0.49 10.7 1.5 2.0 1 1 1 2 2 2 0 Mid domain of argonaute AAA_11 PF13086.6 KHN69754.1 - 0.31 10.8 2.8 0.36 10.6 2.8 1.2 1 0 0 1 1 1 0 AAA domain Ntox16 PF15523.6 KHN69754.1 - 1.2 9.4 7.4 4.5 7.6 0.1 2.9 2 1 0 2 2 2 0 Novel toxin 16 FapA PF03961.13 KHN69754.1 - 6.2 5.3 11.2 2.1 6.8 8.3 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A H-kinase_dim PF02895.14 KHN69755.1 - 0.12 12.8 1.0 0.25 11.8 0.2 2.0 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain TrfA PF07042.11 KHN69756.1 - 0.03 13.4 0.1 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 TrfA protein DUF3222 PF11519.8 KHN69756.1 - 0.044 14.0 0.9 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) zf-C2H2_3 PF13878.6 KHN69756.1 - 0.35 10.7 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF3716 PF12511.8 KHN69758.1 - 0.81 9.8 5.8 0.53 10.4 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Macoilin PF09726.9 KHN69759.1 - 0.057 12.0 2.6 0.067 11.7 2.6 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KHN69759.1 - 0.53 8.5 8.3 0.76 8.0 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 KHN69759.1 - 9.4 5.8 20.0 17 4.9 20.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DEAD PF00270.29 KHN69760.1 - 3.1e-47 160.6 0.0 4.9e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69760.1 - 1.1e-25 90.1 0.0 4.6e-25 88.1 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69760.1 - 7.5e-06 26.1 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KHN69760.1 - 0.0059 15.9 0.2 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 SecA DEAD-like domain Enolase_C PF00113.22 KHN69761.1 - 3.2e-82 276.1 0.0 4.9e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KHN69761.1 - 1.4e-36 125.5 0.0 2.1e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KHN69761.1 - 1.1e-05 25.2 0.0 3.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KHN69761.1 - 0.0029 16.8 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Rpr2 PF04032.16 KHN69762.1 - 1.3e-15 57.4 4.1 1.6e-15 57.2 4.1 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Extensin-like_C PF06904.12 KHN69762.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Extensin-like protein C-terminus Dynamin_M PF01031.20 KHN69763.1 - 1.3e-77 260.9 2.4 1.5e-77 260.6 0.0 2.2 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 KHN69763.1 - 3.5e-50 170.4 0.2 6.9e-50 169.4 0.2 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KHN69763.1 - 6.3e-24 83.9 6.4 1.4e-23 82.9 5.0 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KHN69763.1 - 2.8e-05 24.1 0.1 7e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KHN69763.1 - 0.0015 18.4 0.0 0.13 11.9 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain DcpS_C PF11969.8 KHN69764.1 - 1.1e-17 64.5 4.3 1.6e-17 64.0 0.1 2.4 3 0 0 3 3 3 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KHN69764.1 - 3.2e-08 34.3 0.4 8.3e-08 33.0 0.4 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal ubiquitin PF00240.23 KHN69765.1 - 4.9e-10 39.0 0.1 9.8e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 KHN69765.1 - 2.2e-05 24.3 10.0 0.0019 18.1 2.8 2.6 2 0 0 2 2 2 2 STI1 domain UBA PF00627.31 KHN69765.1 - 0.00025 20.9 0.0 0.00063 19.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TBK1_ULD PF18396.1 KHN69765.1 - 0.018 14.9 0.1 0.11 12.5 0.0 2.0 1 1 1 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain HOIP-UBA PF16678.5 KHN69765.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair CUE PF02845.16 KHN69765.1 - 0.029 14.1 0.1 5.7 6.8 0.0 3.0 2 0 0 2 2 2 0 CUE domain Com_YlbF PF06133.11 KHN69765.1 - 0.032 14.8 4.9 3.3 8.4 0.8 2.7 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Rad60-SLD PF11976.8 KHN69765.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KHN69765.1 - 0.047 14.1 4.1 0.16 12.4 0.1 2.9 2 1 1 3 3 3 0 Ubiquitin-like domain RasGAP_C PF03836.15 KHN69766.1 - 2.4e-20 73.1 0.5 8.3e-20 71.3 0.5 2.0 1 0 0 1 1 1 1 RasGAP C-terminus CH PF00307.31 KHN69766.1 - 1.1e-10 41.6 0.0 2.9e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain RasGAP PF00616.19 KHN69766.1 - 0.00021 21.1 0.2 0.014 15.1 0.0 2.7 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase GCP_C_terminal PF04130.13 KHN69767.1 - 7.6e-14 51.9 0.3 2.2e-13 50.4 0.3 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KHN69767.1 - 1.5e-12 47.7 1.1 2.3e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF4264 PF14084.6 KHN69767.1 - 0.039 13.6 0.0 0.91 9.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Pro_isomerase PF00160.21 KHN69768.1 - 5.8e-41 140.4 0.8 7.6e-41 140.0 0.8 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M17 PF00883.21 KHN69769.1 - 2.5e-114 381.8 0.0 3.3e-114 381.4 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KHN69769.1 - 1.1e-07 31.8 0.2 2e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain HGTP_anticodon PF03129.20 KHN69771.1 - 1.6e-14 53.8 0.0 4.6e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KHN69771.1 - 6.6e-10 39.2 0.1 3.6e-09 36.8 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3160 PF11369.8 KHN69771.1 - 0.15 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) HAD_2 PF13419.6 KHN69773.1 - 3.8e-10 40.1 0.0 6.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KHN69773.1 - 0.021 15.1 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KHN69773.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like TB2_DP1_HVA22 PF03134.19 KHN69774.1 - 2.1e-13 50.0 3.8 3.3e-13 49.4 3.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family VirJ PF06057.11 KHN69774.1 - 0.035 14.0 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3784 PF12650.7 KHN69774.1 - 0.096 12.9 2.7 0.26 11.5 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) IBV_3C PF03620.13 KHN69774.1 - 0.27 11.7 1.8 0.39 11.2 0.6 1.8 1 1 1 2 2 2 0 IBV 3C protein ABC_tran PF00005.27 KHN69775.1 - 1.2e-39 135.9 4.4 3.5e-21 76.2 0.1 3.7 4 0 0 4 4 3 3 ABC transporter ABC_tran_Xtn PF12848.7 KHN69775.1 - 2.3e-23 82.0 0.3 5.4e-23 80.8 0.3 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KHN69775.1 - 2e-16 60.7 0.6 0.0032 17.3 0.1 4.6 5 0 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KHN69775.1 - 6.9e-10 38.7 5.9 0.0019 17.6 0.0 4.6 3 2 2 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KHN69775.1 - 1e-06 29.0 0.1 0.026 14.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KHN69775.1 - 1.9e-06 27.9 0.3 0.0096 15.8 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KHN69775.1 - 5e-06 26.2 1.2 0.022 14.5 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 KHN69775.1 - 1.9e-05 24.6 0.2 0.099 12.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 KHN69775.1 - 2.5e-05 24.1 0.0 0.28 10.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KHN69775.1 - 2.7e-05 24.8 5.8 0.036 14.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 KHN69775.1 - 4.9e-05 22.3 0.1 0.022 13.5 0.0 2.5 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_18 PF13238.6 KHN69775.1 - 4.9e-05 23.9 2.0 0.1 13.2 0.1 3.1 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KHN69775.1 - 0.00014 22.2 0.0 0.057 13.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 KHN69775.1 - 0.00014 22.3 0.0 0.076 13.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KHN69775.1 - 0.00027 20.7 1.2 0.46 10.2 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KHN69775.1 - 0.00047 20.4 0.1 0.27 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KHN69775.1 - 0.00067 20.1 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain TsaE PF02367.17 KHN69775.1 - 0.00081 19.4 1.7 4.3 7.3 0.0 3.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 KHN69775.1 - 0.00082 19.4 2.6 0.81 9.8 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.14 KHN69775.1 - 0.0011 18.8 1.7 0.69 9.8 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 KHN69775.1 - 0.0016 18.7 0.2 1.8 8.8 0.1 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KHN69775.1 - 0.0019 17.8 0.6 1.6 8.3 0.0 2.6 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KHN69775.1 - 0.0024 17.8 1.4 1.7 8.5 0.0 2.8 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea ATP-synt_ab PF00006.25 KHN69775.1 - 0.0041 16.8 0.0 0.18 11.4 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 KHN69775.1 - 0.0046 17.1 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Abhydrolase_7 PF12715.7 KHN69775.1 - 0.0052 16.1 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase family AAA_27 PF13514.6 KHN69775.1 - 0.0061 16.2 0.0 0.67 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KHN69775.1 - 0.0068 16.4 0.9 6.2 6.9 0.3 3.2 3 1 0 3 3 2 0 AAA domain AAA_15 PF13175.6 KHN69775.1 - 0.0074 16.0 19.9 0.065 12.9 0.1 4.1 4 1 0 4 4 3 2 AAA ATPase domain Bac_DnaA PF00308.18 KHN69775.1 - 0.011 15.6 0.2 0.086 12.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 KHN69775.1 - 0.034 13.3 1.2 0.51 9.5 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 KHN69775.1 - 0.037 13.6 1.4 7.3 6.1 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KHN69775.1 - 0.046 13.5 0.1 2.8 7.7 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 KHN69775.1 - 0.05 13.6 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KHN69775.1 - 0.054 12.8 0.3 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 KHN69775.1 - 0.054 13.4 4.9 2.9 7.8 0.1 3.2 4 0 0 4 4 3 0 NTPase Dynamin_N PF00350.23 KHN69775.1 - 0.069 13.2 2.9 0.65 10.0 0.3 3.0 3 0 0 3 3 3 0 Dynamin family AAA_7 PF12775.7 KHN69775.1 - 0.074 12.6 0.4 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PhetRS_B1 PF18262.1 KHN69775.1 - 0.13 12.5 0.0 0.52 10.6 0.0 2.1 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Ploopntkinase3 PF18751.1 KHN69775.1 - 0.15 11.9 0.1 9.5 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IL2 PF00715.17 KHN69775.1 - 0.18 11.8 0.8 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Interleukin 2 SbcCD_C PF13558.6 KHN69775.1 - 0.24 11.7 7.4 0.41 10.9 0.5 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 KHN69775.1 - 0.3 10.3 5.8 5.9 6.1 0.0 3.6 4 0 0 4 4 4 0 Septin DNA_primase_lrg PF04104.14 KHN69776.1 - 2.3e-50 171.5 4.0 3.1e-50 171.1 4.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DEAD_2 PF06733.15 KHN69776.1 - 0.0023 17.6 1.9 0.0041 16.8 0.7 1.9 2 0 0 2 2 2 1 DEAD_2 T2SSE PF00437.20 KHN69776.1 - 0.041 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Syntaxin PF00804.25 KHN69777.1 - 0.0076 16.0 0.6 0.62 9.7 0.2 2.3 1 1 1 2 2 2 2 Syntaxin Syntaxin-6_N PF09177.11 KHN69777.1 - 0.059 13.9 3.6 1.8 9.2 0.0 2.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.6 KHN69777.1 - 0.14 12.6 3.9 0.65 10.4 0.2 2.5 1 1 1 2 2 2 0 Syntaxin-like protein G10 PF01125.17 KHN69778.1 - 2.2e-46 157.3 2.7 2.3e-46 157.2 2.7 1.0 1 0 0 1 1 1 1 G10 protein Glyco_trans_A_1 PF09318.10 KHN69778.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 1 domain A G_glu_transpept PF01019.21 KHN69779.1 - 5.4e-143 477.4 0.0 6.2e-143 477.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DEAD PF00270.29 KHN69781.1 - 1.2e-31 109.9 0.1 1.5e-30 106.3 0.0 2.5 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69781.1 - 1.2e-24 86.7 0.5 9.1e-24 84.0 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69781.1 - 9.6e-08 32.2 0.0 8.4e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Metallophos PF00149.28 KHN69782.1 - 4.3e-15 56.8 0.3 6.5e-15 56.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KHN69782.1 - 9.4e-12 45.4 0.0 3.1e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mre11_DNA_bind PF04152.14 KHN69782.1 - 6.9e-08 33.0 0.0 2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Mre11 DNA-binding presumed domain DUF4897 PF16238.5 KHN69782.1 - 0.098 12.5 0.3 0.098 12.5 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) MJ1316 PF04457.12 KHN69783.1 - 0.026 15.2 0.0 0.41 11.4 0.0 2.4 2 0 0 2 2 2 0 MJ1316 RNA cyclic group end recognition domain Pox_I3 PF04661.12 KHN69783.1 - 0.11 11.6 2.2 0.16 11.1 0.2 1.9 2 0 0 2 2 2 0 Poxvirus I3 ssDNA-binding protein MMM1 PF10296.9 KHN69784.1 - 3.6e-05 23.0 0.1 0.00045 19.4 0.0 2.3 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 LSM PF01423.22 KHN69785.1 - 1.1e-13 50.7 1.0 6.8e-13 48.1 0.3 2.0 1 1 1 2 2 2 2 LSM domain Ribosomal_S4 PF00163.19 KHN69786.1 - 1.3e-07 32.5 0.6 2e-07 31.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KHN69786.1 - 2.4e-06 27.2 0.0 5.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain zf-DBF PF07535.12 KHN69787.1 - 8.3e-16 57.8 1.8 8.3e-16 57.8 1.8 2.0 2 0 0 2 2 2 1 DBF zinc finger Dfp1_Him1_M PF08630.10 KHN69787.1 - 0.0037 17.5 0.4 0.0067 16.6 0.1 1.6 1 1 1 2 2 2 1 Dfp1/Him1, central region Proteasome PF00227.26 KHN69788.1 - 9e-33 113.4 0.0 1.1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KHN69788.1 - 0.0065 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PUA PF01472.20 KHN69789.1 - 8.9e-10 38.4 1.5 1.7e-09 37.5 1.5 1.5 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 KHN69789.1 - 0.0024 18.5 0.6 0.0059 17.3 0.2 1.8 2 1 0 2 2 2 1 Pre-PUA-like domain DUF1947 PF09183.10 KHN69789.1 - 0.045 14.1 3.2 0.11 12.8 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) NTP_transferase PF00483.23 KHN69790.1 - 6.2e-07 29.3 0.0 9.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 KHN69790.1 - 5e-05 22.4 0.2 9.5e-05 21.5 0.2 1.4 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 KHN69790.1 - 0.00011 21.8 3.7 0.0032 17.1 1.7 3.2 1 1 3 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KHN69790.1 - 0.0012 19.2 0.0 0.0016 18.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KHN69790.1 - 1.1 9.0 6.1 6.4 6.6 2.9 3.5 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Peptidase_M48 PF01435.18 KHN69791.1 - 3.1e-10 40.1 0.0 6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Glutaredoxin PF00462.24 KHN69792.1 - 1e-14 54.4 0.0 7.4e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Peptidase_M48 PF01435.18 KHN69793.1 - 3.1e-11 43.4 0.0 7.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M48 DUF4149 PF13664.6 KHN69793.1 - 1.1 9.6 9.2 0.46 10.8 6.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Proteasome PF00227.26 KHN69794.1 - 1.2e-46 158.6 0.0 1.5e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KHN69794.1 - 7.7e-10 38.3 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TPR_7 PF13176.6 KHN69795.1 - 0.031 14.3 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Arrestin_N PF00339.29 KHN69796.1 - 2.5e-08 34.1 0.0 5.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KHN69796.1 - 5.8e-07 30.0 0.1 0.0014 19.1 0.1 2.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 KHN69796.1 - 0.025 14.1 0.0 0.69 9.4 0.0 2.6 3 0 0 3 3 3 0 SpoOM protein PTPLA PF04387.14 KHN69797.1 - 5.3e-20 71.8 16.0 1.6e-19 70.3 16.0 1.7 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA RRM_1 PF00076.22 KHN69798.1 - 2.6e-12 46.4 1.4 2.5e-08 33.6 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KHN69798.1 - 0.00014 21.9 0.1 0.017 15.2 0.1 2.4 1 1 1 2 2 2 1 RNA recognition motif RL PF17797.1 KHN69798.1 - 0.0032 17.4 0.4 1.5 8.8 0.1 2.3 2 0 0 2 2 2 2 RL domain Nup35_RRM_2 PF14605.6 KHN69798.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif cwf18 PF08315.12 KHN69798.1 - 0.26 12.0 1.4 0.69 10.6 1.4 1.6 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor MBOAT PF03062.19 KHN69800.1 - 2.6e-14 53.3 14.9 6.2e-14 52.1 14.9 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Dcc1 PF09724.9 KHN69801.1 - 0.0033 16.8 0.1 0.36 10.1 0.0 2.1 1 1 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 DUF2120 PF09893.9 KHN69801.1 - 0.011 15.8 0.2 0.023 14.8 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Sas10_Utp3 PF04000.15 KHN69802.1 - 0.0042 17.7 0.2 0.01 16.4 0.2 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Sas10 PF09368.10 KHN69802.1 - 0.0052 17.2 7.9 0.012 16.1 7.9 1.6 1 0 0 1 1 1 1 Sas10 C-terminal domain Ribosomal_L7Ae PF01248.26 KHN69803.1 - 3.7e-12 45.8 0.0 4.3e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ubiquitin PF00240.23 KHN69804.1 - 0.0018 18.0 0.1 0.002 17.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KHN69804.1 - 0.014 15.2 0.2 0.017 14.9 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BING4CT PF08149.11 KHN69805.1 - 2.5e-28 97.7 0.1 1.9e-27 94.9 0.0 2.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KHN69805.1 - 2.1e-05 24.7 0.3 2.6 8.4 0.0 4.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KHN69805.1 - 0.00069 20.4 4.8 0.0045 17.8 0.1 4.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Pkinase PF00069.25 KHN69806.1 - 8e-63 212.3 1.2 9.3e-63 212.0 1.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN69806.1 - 5.5e-29 101.2 0.2 7.3e-29 100.8 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KHN69806.1 - 3.8e-07 30.3 0.0 0.00025 21.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KHN69806.1 - 0.0018 17.9 2.8 0.0081 15.8 0.6 2.4 2 1 0 2 2 2 1 Choline/ethanolamine kinase FTA2 PF13095.6 KHN69806.1 - 0.041 13.5 0.6 1.1 8.8 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2555 PF10742.9 KHN69806.1 - 0.065 13.1 0.1 5.5 6.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) FliG_N PF14842.6 KHN69806.1 - 0.13 12.8 0.1 0.37 11.3 0.1 1.7 1 1 1 2 2 2 0 FliG N-terminal domain Imm41 PF15592.6 KHN69806.1 - 4 7.8 7.4 8 6.8 0.8 2.7 1 1 1 2 2 2 0 Immunity protein 41 4HBT_3 PF13622.6 KHN69807.1 - 6e-21 75.8 0.0 7.2e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KHN69807.1 - 5.1e-10 39.3 0.0 2.4e-06 27.4 0.0 2.7 2 1 1 3 3 3 2 Acyl-CoA thioesterase ORF45 PF17620.2 KHN69807.1 - 0.065 13.3 3.2 0.35 11.0 3.2 2.0 1 1 0 1 1 1 0 Family of unknown function RFC1 PF08519.12 KHN69808.1 - 5.6e-33 114.3 0.1 9.5e-33 113.6 0.1 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.29 KHN69808.1 - 7.8e-14 52.2 0.1 1.8e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 KHN69808.1 - 1.1e-11 44.9 0.0 3.1e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 KHN69808.1 - 1.3e-08 35.0 0.0 2.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 KHN69808.1 - 7.9e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KHN69808.1 - 1e-05 25.5 0.2 0.0019 18.1 0.0 3.2 2 1 1 3 3 3 1 NTPase AAA_14 PF13173.6 KHN69808.1 - 4.2e-05 23.6 0.1 0.0001 22.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KHN69808.1 - 0.00016 21.1 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.22 KHN69808.1 - 0.00017 21.9 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KHN69808.1 - 0.00049 20.1 0.0 0.0029 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KHN69808.1 - 0.0011 18.3 0.1 0.0031 16.8 0.1 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KHN69808.1 - 0.0012 19.1 0.0 0.043 14.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain PTCB-BRCT PF12738.7 KHN69808.1 - 0.0027 17.6 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 1 1 twin BRCT domain AAA_16 PF13191.6 KHN69808.1 - 0.0027 18.1 0.0 0.005 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KHN69808.1 - 0.0031 17.5 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KHN69808.1 - 0.0035 17.3 1.1 0.039 13.9 0.1 2.5 3 0 0 3 3 2 1 NACHT domain Sigma54_activ_2 PF14532.6 KHN69808.1 - 0.0047 17.1 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KHN69808.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DNA_pol3_delta2 PF13177.6 KHN69808.1 - 0.017 14.9 0.3 0.23 11.2 0.0 2.7 2 1 1 3 3 3 0 DNA polymerase III, delta subunit DUF815 PF05673.13 KHN69808.1 - 0.019 14.1 0.1 0.045 12.9 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KHN69808.1 - 0.022 15.3 0.0 0.075 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KHN69808.1 - 0.025 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 KHN69808.1 - 0.029 14.8 0.0 0.2 12.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KHN69808.1 - 0.037 13.2 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KHN69808.1 - 0.044 13.3 0.2 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 KHN69808.1 - 0.064 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KHN69808.1 - 0.068 12.9 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.29 KHN69808.1 - 0.083 12.7 0.1 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.6 KHN69808.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KHN69808.1 - 0.13 12.7 0.1 0.57 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_assoc_2 PF16193.5 KHN69808.1 - 0.15 12.4 0.1 0.54 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA C-terminal domain Viral_helicase1 PF01443.18 KHN69808.1 - 0.16 11.7 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 KHN69808.1 - 0.16 11.7 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Corazonin PF17308.2 KHN69809.1 - 0.092 13.1 0.3 0.14 12.6 0.3 1.2 1 0 0 1 1 1 0 Pro-corazonin PCI PF01399.27 KHN69810.1 - 5.1e-14 52.7 1.1 1e-13 51.7 0.1 2.0 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.9 KHN69810.1 - 0.011 15.4 0.2 0.039 13.7 0.1 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 CSN8_PSD8_EIF3K PF10075.9 KHN69810.1 - 0.12 12.3 0.7 0.55 10.2 0.1 2.4 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family GTP_EFTU PF00009.27 KHN69813.1 - 1.8e-32 112.5 0.0 6e-31 107.5 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D4 PF14578.6 KHN69813.1 - 6.8e-17 61.2 0.1 3.5e-16 58.9 0.1 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 4 IF-2 PF11987.8 KHN69813.1 - 4.5e-13 49.2 3.1 7.1e-13 48.6 1.7 2.1 1 1 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KHN69813.1 - 4.2e-09 36.7 6.0 4.6e-07 30.1 0.0 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KHN69813.1 - 7.5e-07 29.2 0.4 2.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KHN69813.1 - 2.2e-05 24.7 0.0 5.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KHN69813.1 - 0.0082 15.6 0.0 0.027 13.9 0.0 2.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KHN69813.1 - 0.023 14.3 0.0 0.086 12.4 0.0 2.0 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 KHN69813.1 - 0.032 14.0 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF5010_C PF18099.1 KHN69815.1 - 0.027 14.6 0.0 0.093 12.9 0.0 1.9 1 0 0 1 1 1 0 DUF5010 C-terminal domain zf-C3HC4_3 PF13920.6 KHN69816.1 - 3.1e-08 33.3 12.3 3.1e-08 33.3 12.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KHN69816.1 - 2.9e-05 23.8 13.4 2.9e-05 23.8 13.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KHN69816.1 - 8.7e-05 22.3 15.8 8.7e-05 22.3 15.8 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KHN69816.1 - 0.00047 20.4 13.8 0.00047 20.4 13.8 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KHN69816.1 - 0.00058 19.7 11.6 0.0021 17.9 11.6 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KHN69816.1 - 0.00076 19.4 8.1 0.00076 19.4 8.1 2.4 2 1 1 3 3 2 1 RING-type zinc-finger TMF_TATA_bd PF12325.8 KHN69816.1 - 0.0077 16.4 3.8 0.0077 16.4 3.8 6.6 1 1 3 5 5 5 1 TATA element modulatory factor 1 TATA binding zf-RING_5 PF14634.6 KHN69816.1 - 0.014 15.4 14.0 0.059 13.3 14.0 2.2 1 0 0 1 1 1 0 zinc-RING finger domain CENP-Q PF13094.6 KHN69816.1 - 0.014 15.6 3.6 0.014 15.6 3.6 3.3 2 2 2 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_6 PF14835.6 KHN69816.1 - 0.027 14.3 5.0 0.067 13.1 5.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KHN69816.1 - 0.75 10.0 17.0 0.088 13.0 11.7 2.3 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING T3SSipB PF16535.5 KHN69816.1 - 1 9.9 8.8 0.73 10.3 0.2 3.4 2 1 1 3 3 3 0 Type III cell invasion protein SipB DUF948 PF06103.11 KHN69816.1 - 1 9.7 6.5 7.5 6.9 0.2 3.9 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-RING_4 PF14570.6 KHN69816.1 - 4.2 7.2 12.1 12 5.8 12.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KHN69816.1 - 6.1 7.2 15.8 0.38 11.1 7.7 3.1 3 0 0 3 3 3 0 RING-H2 zinc finger domain Shugoshin_N PF07558.11 KHN69816.1 - 8 6.4 18.8 0.2 11.5 0.3 3.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region SecY PF00344.20 KHN69819.1 - 3.3e-58 197.3 17.4 4.3e-58 197.0 17.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KHN69819.1 - 1.1e-17 63.6 0.1 3.5e-17 61.9 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Peptidase_M22 PF00814.25 KHN69820.1 - 5.5e-83 278.8 0.0 6.6e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KHN69820.1 - 0.09 12.4 0.0 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus HA2 PF04408.23 KHN69821.1 - 4.4e-16 59.1 0.0 1.1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KHN69821.1 - 1.2e-13 51.4 0.0 6e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KHN69821.1 - 1.3e-06 28.3 0.4 5.7e-06 26.2 0.4 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KHN69821.1 - 3.9e-06 27.1 0.0 1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KHN69821.1 - 1.4e-05 25.4 0.0 3.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KHN69821.1 - 0.00062 19.2 0.7 0.011 15.1 0.0 2.8 3 0 0 3 3 3 1 KaiC IstB_IS21 PF01695.17 KHN69821.1 - 0.0021 17.8 0.2 4.9 6.8 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein Flavi_DEAD PF07652.14 KHN69821.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.6 KHN69821.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KHN69821.1 - 0.021 13.9 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KHN69821.1 - 0.023 14.2 0.1 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 KHN69821.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KHN69821.1 - 0.049 14.2 0.1 0.22 12.0 0.1 2.0 1 1 1 2 2 2 0 ABC transporter ResIII PF04851.15 KHN69821.1 - 0.051 13.6 0.3 2.7 7.9 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 KHN69821.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.6 KHN69821.1 - 0.11 12.6 0.1 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 KHN69821.1 - 0.15 12.4 0.1 0.47 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KHN69821.1 - 0.18 10.9 5.6 7.1 5.7 0.0 3.3 4 0 0 4 4 4 0 NB-ARC domain Ras PF00071.22 KHN69823.1 - 5.1e-42 143.2 0.4 5.8e-42 143.0 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN69823.1 - 1e-29 103.2 0.5 1.4e-29 102.8 0.5 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN69823.1 - 2e-19 69.7 0.2 2.5e-19 69.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KHN69823.1 - 2.7e-08 33.6 0.2 3.8e-06 26.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KHN69823.1 - 1.2e-07 31.8 0.2 1.9e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KHN69823.1 - 2.6e-06 27.5 0.4 0.033 14.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KHN69823.1 - 4.4e-05 23.0 0.1 6.2e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KHN69823.1 - 5.6e-05 22.6 0.1 7.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KHN69823.1 - 0.0024 17.6 0.3 0.044 13.5 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KHN69823.1 - 0.0041 16.7 0.4 0.049 13.2 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 KHN69823.1 - 0.0046 16.9 0.1 0.0069 16.4 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 KHN69823.1 - 0.0047 16.7 0.1 0.13 12.1 0.0 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 KHN69823.1 - 0.016 15.6 0.0 0.032 14.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KHN69823.1 - 0.02 13.9 0.2 0.053 12.5 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KHN69823.1 - 0.024 14.4 1.4 0.12 12.0 1.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KHN69823.1 - 0.043 13.8 0.3 0.13 12.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN69823.1 - 0.06 13.6 0.1 0.23 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KHN69823.1 - 0.094 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KHN69823.1 - 0.12 11.8 0.8 0.13 11.6 0.1 1.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cyc-maltodext_C PF10438.9 KHN69823.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain VWA_3 PF13768.6 KHN69823.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Lectin_C_term PF18022.1 KHN69824.1 - 0.059 13.8 0.5 5.9 7.4 0.1 2.9 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin C-terminal domain RNA_pol_Rpb1_3 PF04983.18 KHN69824.1 - 0.47 10.4 2.8 2.3 8.2 1.0 2.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 3 DUF5394 PF17372.2 KHN69824.1 - 0.63 9.6 6.3 5.2 6.6 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5394) LRR_8 PF13855.6 KHN69825.1 - 8.4e-21 73.5 39.1 6.3e-09 35.5 2.3 2.9 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KHN69825.1 - 1.7e-11 44.1 38.4 7.7e-07 29.3 4.2 3.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) PARP_reg PF02877.14 KHN69825.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain LRR_9 PF14580.6 KHN69825.1 - 0.028 13.9 6.7 0.18 11.3 1.9 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KHN69825.1 - 0.063 13.8 14.3 4.8 8.1 0.1 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 KHN69825.1 - 0.25 11.5 7.2 13 6.2 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 KHN69826.1 - 1.3e-33 114.6 31.9 7e-10 38.5 1.8 6.7 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 KHN69826.1 - 2.3e-23 81.9 40.6 3.9e-05 23.9 0.4 7.5 4 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KHN69826.1 - 2.8e-15 56.3 17.0 3.1e-07 30.0 0.3 3.1 2 1 1 3 3 3 3 Leucine-rich repeat DUF268 PF03269.14 KHN69826.1 - 0.16 11.8 0.2 20 5.0 0.0 2.3 1 1 1 2 2 2 0 Caenorhabditis protein of unknown function, DUF268 LRR_6 PF13516.6 KHN69826.1 - 0.91 9.7 0.0 0.91 9.7 0.0 8.7 10 0 0 10 10 10 0 Leucine Rich repeat LRR_1 PF00560.33 KHN69826.1 - 3.1 8.7 44.6 8.7 7.3 0.3 10.2 9 3 0 9 9 9 0 Leucine Rich Repeat CCAP PF11105.8 KHN69827.1 - 0.12 12.3 1.2 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a AAA PF00004.29 KHN69828.1 - 6.6e-05 23.4 1.8 0.001 19.5 1.8 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KHN69828.1 - 0.006 15.9 1.4 1 8.5 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KHN69828.1 - 0.0067 16.7 2.9 0.2 11.9 0.1 3.2 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 KHN69828.1 - 0.0076 16.6 1.3 0.14 12.5 0.2 2.3 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KHN69828.1 - 0.013 15.3 0.1 0.031 14.0 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 KHN69828.1 - 0.014 14.6 0.2 0.084 12.1 0.2 2.1 1 1 0 1 1 1 0 KAP family P-loop domain AAA_7 PF12775.7 KHN69828.1 - 0.021 14.3 0.8 0.34 10.4 0.2 2.4 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KHN69828.1 - 0.056 13.6 0.1 0.095 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KHN69828.1 - 0.058 13.1 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KHN69828.1 - 0.073 13.2 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 KHN69828.1 - 0.073 12.9 0.5 0.2 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KHN69828.1 - 0.077 13.4 1.2 0.22 11.9 0.1 2.3 2 1 1 3 3 3 0 RNA helicase AAA_16 PF13191.6 KHN69828.1 - 0.083 13.3 0.1 2.9 8.2 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KHN69828.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KHN69828.1 - 0.12 12.2 0.2 0.49 10.1 0.2 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase DHHC PF01529.20 KHN69829.1 - 8.7e-29 100.3 15.1 8.7e-29 100.3 15.1 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.25 KHN69829.1 - 0.043 14.4 3.6 0.043 14.4 3.6 2.3 2 0 0 2 2 2 0 Plexin repeat Yip1 PF04893.17 KHN69829.1 - 0.43 10.3 12.2 1.3 8.7 1.6 2.2 2 0 0 2 2 2 0 Yip1 domain DUF4199 PF13858.6 KHN69829.1 - 0.79 10.1 8.9 3.1 8.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Ribosomal_L40e PF01020.17 KHN69829.1 - 0.89 9.5 10.6 1.6 8.7 10.6 1.3 1 0 0 1 1 1 0 Ribosomal L40e family SRTM1 PF15872.5 KHN69829.1 - 1.2 9.3 11.6 1.1 9.4 4.3 2.7 2 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 DUF5095 PF17016.5 KHN69830.1 - 4.7e-57 193.4 9.7 5.7e-57 193.2 9.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5095) HTH_9 PF08221.11 KHN69831.1 - 2.1e-17 63.0 0.3 2e-15 56.6 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KHN69831.1 - 0.00088 19.1 0.7 0.074 12.9 0.2 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit TrmB PF01978.19 KHN69831.1 - 0.0045 16.9 0.2 17 5.4 0.0 4.0 3 1 0 3 3 3 1 Sugar-specific transcriptional regulator TrmB Mnd1 PF03962.15 KHN69831.1 - 0.036 14.4 0.8 7.3 7.0 0.0 3.2 3 0 0 3 3 3 0 Mnd1 HTH domain DUF5087 PF17006.5 KHN69832.1 - 7.4e-87 291.6 1.1 1.4e-86 290.7 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5087) DUF3818 PF12825.7 KHN69832.1 - 0.014 14.4 5.0 0.0096 15.0 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) GT-D PF08759.11 KHN69832.1 - 0.018 14.7 2.6 0.035 13.8 2.6 1.5 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Anti-adapt_IraP PF10796.9 KHN69832.1 - 0.035 14.7 2.1 0.046 14.3 0.6 2.0 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein PKcGMP_CC PF16808.5 KHN69832.1 - 0.082 12.8 1.4 0.18 11.7 1.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2785 PF10978.8 KHN69832.1 - 0.1 12.4 0.2 8 6.2 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2785) Titin_Ig-rpts PF06582.12 KHN69832.1 - 0.11 12.4 1.1 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Titin repeat TRAF_BIRC3_bd PF16673.5 KHN69832.1 - 7.2 6.5 10.5 0.91 9.4 5.8 2.0 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain TAF4 PF05236.14 KHN69833.1 - 1.8e-17 64.0 8.4 4.5e-16 59.4 8.4 2.3 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family VHP PF02209.19 KHN69833.1 - 0.15 12.1 0.5 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Villin headpiece domain PBS_linker_poly PF00427.21 KHN69833.1 - 4.2 7.4 7.1 0.84 9.7 0.1 2.9 4 0 0 4 4 4 0 Phycobilisome Linker polypeptide Zw10 PF06248.13 KHN69834.1 - 0.016 13.8 1.8 0.017 13.7 1.8 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF2968 PF11180.8 KHN69834.1 - 0.04 13.6 0.3 0.046 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) bZIP_2 PF07716.15 KHN69834.1 - 0.045 13.8 1.5 0.13 12.4 1.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper DUF4795 PF16043.5 KHN69834.1 - 0.38 10.3 5.5 0.53 9.9 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF5096 PF17019.5 KHN69835.1 - 1.6e-54 184.7 1.7 2.2e-54 184.2 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5096) DUF2642 PF10842.8 KHN69835.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) CH PF00307.31 KHN69836.1 - 5e-49 165.0 3.2 1.3e-25 89.7 0.2 3.8 3 1 1 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KHN69836.1 - 2.6e-13 49.6 0.0 3.5e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 KHN69836.1 - 0.0004 20.4 4.6 0.014 15.5 0.0 3.7 3 1 0 4 4 4 1 CH-like domain in sperm protein HBM PF16591.5 KHN69836.1 - 0.029 13.8 0.5 0.061 12.7 0.5 1.5 1 0 0 1 1 1 0 Helical bimodular sensor domain sCache_2 PF17200.4 KHN69836.1 - 0.039 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Single Cache domain 2 Drf_FH3 PF06367.16 KHN69836.1 - 2.7 7.6 10.9 0.92 9.1 6.3 2.6 2 1 0 2 2 2 0 Diaphanous FH3 Domain RhoGAP PF00620.27 KHN69837.1 - 9.2e-19 67.8 0.3 3.4e-18 65.9 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain RVT_1 PF00078.27 KHN69838.1 - 1.6e-17 63.8 1.0 9.5e-11 41.6 0.1 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.8 KHN69838.1 - 2e-17 63.6 15.1 2e-17 63.6 15.1 2.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain PPR_1 PF12854.7 KHN69839.1 - 0.0034 17.1 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 PPR repeat RAMP PF04901.13 KHN69839.1 - 0.06 13.3 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Receptor activity modifying family Proteasome PF00227.26 KHN69840.1 - 3.5e-27 95.1 0.1 4.1e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KHN69840.1 - 0.0025 17.4 0.1 0.0044 16.7 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DWNN PF08783.11 KHN69841.1 - 1.4e-22 79.7 0.1 2.5e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KHN69841.1 - 1.3e-10 40.9 4.8 1.3e-10 40.9 4.8 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-RING_UBOX PF13445.6 KHN69841.1 - 6.6e-05 22.9 9.9 0.00017 21.5 9.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KHN69841.1 - 0.00051 20.1 9.6 0.00051 20.1 9.6 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KHN69841.1 - 0.0057 16.6 14.2 0.0057 16.6 14.2 2.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-CCHC PF00098.23 KHN69841.1 - 0.018 15.1 5.2 0.018 15.1 5.2 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-C3HC4_3 PF13920.6 KHN69841.1 - 0.034 14.0 12.9 0.034 14.0 12.9 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 KHN69841.1 - 0.089 12.5 0.4 0.089 12.5 0.4 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger ArfGap PF01412.18 KHN69841.1 - 1.4 9.0 12.7 0.066 13.3 5.3 2.3 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Rubredoxin PF00301.20 KHN69841.1 - 2.3 8.3 8.8 16 5.6 0.0 4.0 5 0 0 5 5 5 0 Rubredoxin NOC3p PF07540.11 KHN69842.1 - 2e-14 53.8 0.1 4.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Nucleolar complex-associated protein PIN_6 PF17146.4 KHN69843.1 - 3.2e-14 53.2 0.2 1.1e-13 51.5 0.3 1.8 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KHN69843.1 - 9.6e-10 38.5 3.8 2.1e-09 37.4 3.8 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Phospholip_A2_2 PF05826.12 KHN69843.1 - 0.021 15.0 2.3 0.039 14.2 2.3 1.4 1 0 0 1 1 1 0 Phospholipase A2 CBFD_NFYB_HMF PF00808.23 KHN69844.1 - 4.4e-05 23.7 1.1 0.00023 21.4 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NUC153 PF08159.12 KHN69845.1 - 6.3e-11 41.9 0.7 2e-10 40.3 0.7 1.9 1 0 0 1 1 1 1 NUC153 domain Ribosomal_L39 PF00832.20 KHN69846.1 - 4.5e-13 48.6 6.7 5.4e-13 48.3 6.7 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein mRNA_cap_enzyme PF01331.19 KHN69847.1 - 6.4e-29 101.2 0.9 2.1e-28 99.5 0.9 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KHN69847.1 - 1.4e-10 41.8 0.0 4.9e-10 40.0 0.0 1.9 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KHN69847.1 - 0.003 17.2 0.4 1.5 8.4 0.2 3.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain SNF2_N PF00176.23 KHN69848.1 - 6.9e-52 176.3 1.4 1.4e-50 172.0 1.4 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KHN69848.1 - 2.2e-22 79.5 0.0 1.3e-21 77.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69848.1 - 5.1e-11 42.9 1.2 2.4e-10 40.7 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KHN69848.1 - 0.00018 20.8 0.1 0.00051 19.3 0.1 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KHN69848.1 - 0.0017 18.1 0.0 0.027 14.2 0.0 2.5 2 0 0 2 2 2 1 SWI2/SNF2 ATPase Cys_rich_FGFR PF00839.17 KHN69848.1 - 0.11 12.7 1.6 2.1 8.6 0.5 2.8 2 0 0 2 2 2 0 Cysteine rich repeat MIEAP PF16026.5 KHN69849.1 - 0.015 15.5 0.4 0.05 13.8 0.2 1.9 1 1 1 2 2 2 0 Mitochondria-eating protein COG4 PF08318.12 KHN69849.1 - 0.025 13.7 0.5 0.92 8.5 0.0 2.5 2 1 0 2 2 2 0 COG4 transport protein DUF1932 PF09130.11 KHN69849.1 - 0.12 12.4 0.1 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) DNA_pol_B PF00136.21 KHN69851.1 - 2.6e-133 445.1 0.7 2.6e-133 445.1 0.7 1.7 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KHN69851.1 - 3.3e-66 223.8 0.5 6.6e-66 222.7 0.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KHN69851.1 - 6.5e-14 52.2 9.9 1.4e-13 51.1 9.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KHN69851.1 - 1.1e-05 24.5 0.4 7.1e-05 21.8 0.1 2.4 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KHN69851.1 - 0.005 16.5 0.0 0.079 12.6 0.0 2.2 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.20 KHN69851.1 - 0.12 12.1 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 3'-5' exonuclease RNase_H_2 PF13482.6 KHN69851.1 - 0.12 12.3 0.0 1.1 9.2 0.0 2.4 1 1 0 1 1 1 0 RNase_H superfamily CENP-T_C PF15511.6 KHN69852.1 - 1.8e-05 24.8 0.0 2.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KHN69852.1 - 8.9e-05 22.9 1.3 0.00022 21.6 1.3 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KHN69852.1 - 0.00018 21.7 0.2 0.00039 20.7 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 KHN69852.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KHN69852.1 - 0.0029 18.0 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KHN69852.1 - 0.0052 16.8 0.0 0.0078 16.3 0.0 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KHN69852.1 - 0.034 14.2 0.0 0.041 13.9 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated Histone PF00125.24 KHN69853.1 - 1.5e-41 141.8 0.1 1.7e-41 141.6 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KHN69853.1 - 3e-06 27.4 0.0 5.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KHN69853.1 - 0.0084 16.5 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KHN69853.1 - 0.037 14.6 0.9 0.045 14.3 0.9 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain TAF PF02969.17 KHN69853.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 KHN69853.1 - 0.087 13.0 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold LRR_4 PF12799.7 KHN69854.1 - 1.5e-20 72.9 31.4 2e-07 31.2 2.9 5.6 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KHN69854.1 - 1.3e-15 56.9 16.3 4.8e-05 23.0 1.2 5.2 2 1 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 KHN69854.1 - 3.4e-09 36.0 8.6 0.63 10.2 0.1 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_9 PF14580.6 KHN69854.1 - 1.1e-06 28.3 14.0 6.4e-05 22.5 3.1 2.2 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KHN69854.1 - 7.6e-05 22.7 15.4 7 7.6 1.1 6.8 7 1 0 7 7 7 2 Leucine Rich Repeat MS_channel PF00924.18 KHN69855.1 - 3.4e-06 26.7 0.0 4.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Cpn60_TCP1 PF00118.24 KHN69856.1 - 3.9e-129 431.5 5.0 4.4e-129 431.3 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nic96 PF04097.14 KHN69857.1 - 3e-13 49.1 0.0 3.2e-11 42.4 0.0 2.7 2 1 0 2 2 2 2 Nup93/Nic96 baeRF_family8 PF18851.1 KHN69857.1 - 0.54 10.3 3.2 27 4.8 0.0 3.0 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 8 DUF2089 PF09862.9 KHN69858.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) CUT PF02376.15 KHN69858.1 - 0.087 13.0 0.0 0.3 11.3 0.0 1.8 1 1 1 2 2 2 0 CUT domain DUF2439 PF10382.9 KHN69859.1 - 9.6e-12 45.1 1.3 2.3e-11 43.9 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) PLA2_B PF01735.18 KHN69859.1 - 0.0015 17.1 2.3 0.0017 16.9 2.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Noc2 PF03715.13 KHN69860.1 - 1.9e-15 56.9 2.9 2.6e-15 56.5 2.9 1.1 1 0 0 1 1 1 1 Noc2p family DnaJ PF00226.31 KHN69861.1 - 8.6e-09 35.4 1.1 1.3e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 KHN69861.1 - 0.0011 19.4 0.0 1 9.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_S30 PF01577.16 KHN69861.1 - 0.069 12.8 7.5 0.11 12.1 7.5 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Ribosomal_S14 PF00253.21 KHN69862.1 - 1.3e-07 31.3 1.9 1.7e-07 30.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S7 PF00177.21 KHN69864.1 - 4.5e-31 107.5 2.2 5.6e-31 107.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Doppel PF11466.8 KHN69865.1 - 0.0098 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Prion-like protein Doppel RRM_1 PF00076.22 KHN69866.1 - 0.0023 17.7 0.2 0.059 13.2 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ERO1 PF04137.15 KHN69867.1 - 2.1e-23 83.1 4.9 2.4e-19 69.8 4.9 3.1 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TFIIS_M PF07500.14 KHN69868.1 - 4e-22 78.8 2.5 7.7e-22 77.9 2.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KHN69868.1 - 1.3e-17 63.3 8.3 1.1e-16 60.3 7.1 2.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) KH_1 PF00013.29 KHN69869.1 - 1e-08 34.8 0.4 3.1e-08 33.3 0.1 2.0 3 0 0 3 3 3 1 KH domain DUF749 PF05370.11 KHN69869.1 - 0.024 14.7 0.2 6.5 6.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF749) B56 PF01603.20 KHN69870.1 - 9.2e-23 80.9 0.2 1.5e-22 80.2 0.2 1.2 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CTD_bind PF04818.13 KHN69870.1 - 0.025 15.4 0.5 4.7 8.1 0.1 3.2 3 0 0 3 3 3 0 RNA polymerase II-binding domain. Sugar_tr PF00083.24 KHN69871.1 - 1.6e-38 132.7 38.4 7.5e-24 84.4 12.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KHN69871.1 - 4.1e-11 42.4 43.0 3.9e-08 32.6 18.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KHN69871.1 - 2.7e-05 23.7 8.4 4.4e-05 22.9 8.4 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Myb_DNA-binding PF00249.31 KHN69872.1 - 7.2e-06 26.1 0.3 2.8e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF313 PF03754.13 KHN69872.1 - 0.04 14.1 1.0 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF313) Mad3_BUB1_I_2 PF17014.5 KHN69873.1 - 2.8e-38 130.9 5.0 4.9e-38 130.2 2.1 2.3 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Mad3_BUB1_I PF08311.12 KHN69873.1 - 6.9e-08 32.5 0.3 1.7e-07 31.3 0.3 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 DUF3641 PF12345.8 KHN69873.1 - 0.028 14.4 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3641) Helicase_C PF00271.31 KHN69874.1 - 4.5e-10 39.9 0.1 2.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KHN69874.1 - 8.6e-08 32.1 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.6 KHN69874.1 - 2.2e-05 24.4 0.0 0.14 12.0 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KHN69874.1 - 0.00062 19.8 0.0 0.0017 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN69874.1 - 0.0007 19.9 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 KHN69874.1 - 0.0032 17.8 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.15 KHN69874.1 - 0.0037 17.3 0.0 0.049 13.6 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KHN69874.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Adeno_IVa2 PF02456.15 KHN69874.1 - 0.016 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.15 KHN69874.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 KHN69874.1 - 0.029 14.1 0.0 0.097 12.4 0.0 1.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 KHN69874.1 - 0.043 14.3 0.1 0.11 13.0 0.1 1.6 1 0 0 1 1 1 0 ABC transporter Helicase_RecD PF05127.14 KHN69874.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Helicase T2SSE PF00437.20 KHN69874.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DHHC PF01529.20 KHN69875.1 - 1.2e-29 103.1 17.7 1.2e-29 103.1 17.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-AN1 PF01428.16 KHN69876.1 - 2.9e-08 33.7 13.7 5.5e-08 32.8 13.7 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ssl1 PF04056.14 KHN69877.1 - 6.4e-25 88.1 0.0 9.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like DNA_ligase_ZBD PF03119.16 KHN69877.1 - 0.51 10.4 7.0 1.9 8.6 0.1 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 KHN69877.1 - 1.4 9.0 18.6 37 4.5 18.0 2.6 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.12 KHN69877.1 - 7.6 6.9 26.4 0.2 11.9 14.7 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain Y_phosphatase PF00102.27 KHN69879.1 - 1.4e-18 67.3 0.0 3e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KHN69879.1 - 9.6e-06 25.4 0.1 2.5e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 KHN69879.1 - 0.00032 20.8 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KHN69879.1 - 0.062 13.4 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate RPN1_RPN2_N PF17781.1 KHN69880.1 - 1.5e-31 109.9 0.6 2.5e-31 109.2 0.6 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 KHN69880.1 - 2.7e-11 43.3 0.3 0.0046 17.3 0.1 6.2 6 0 0 6 6 6 2 Proteasome/cyclosome repeat RPN1_C PF18051.1 KHN69880.1 - 3.6e-06 26.9 0.0 7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal zf-CCCH_8 PF18633.1 KHN69880.1 - 0.075 13.1 0.5 0.21 11.7 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 Lipase_3 PF01764.25 KHN69881.1 - 3.8e-19 69.0 0.0 7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 KHN69881.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 KHN69881.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Ribosomal_L27e PF01777.18 KHN69882.1 - 5.7e-09 36.2 1.0 9.1e-09 35.6 1.0 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family Tautomerase PF01361.21 KHN69882.1 - 0.028 14.3 0.4 0.52 10.3 0.1 2.3 2 0 0 2 2 2 0 Tautomerase enzyme KOW PF00467.29 KHN69882.1 - 0.06 13.3 1.2 0.12 12.4 1.2 1.4 1 0 0 1 1 1 0 KOW motif DNA_topoisoIV PF00521.20 KHN69884.1 - 3.1e-120 401.9 0.3 5.6e-120 401.1 0.3 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KHN69884.1 - 4.4e-46 156.3 2.5 8.8e-46 155.3 0.6 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KHN69884.1 - 5.4e-20 71.6 0.2 1.4e-19 70.3 0.2 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KHN69884.1 - 4.6e-14 52.9 0.0 1.1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KHN69884.1 - 5.3e-08 33.0 0.0 1.8e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain EF-hand_10 PF14788.6 KHN69885.1 - 0.064 13.1 1.4 0.13 12.1 1.4 1.6 1 0 0 1 1 1 0 EF hand MARVEL PF01284.23 KHN69887.1 - 5.9 6.9 12.4 3.5 7.7 8.4 2.8 1 1 1 2 2 2 0 Membrane-associating domain MgtE PF01769.16 KHN69888.1 - 8.9e-18 64.9 32.4 3e-12 47.0 8.4 3.1 2 1 1 3 3 3 2 Divalent cation transporter HSF_DNA-bind PF00447.17 KHN69889.1 - 5.1e-17 62.3 0.0 8.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF919 PF06034.11 KHN69890.1 - 0.055 13.3 0.3 0.22 11.4 0.3 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF4795 PF16043.5 KHN69890.1 - 2.9 7.5 8.0 0.93 9.1 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) JAB PF01398.21 KHN69892.1 - 2.8e-23 82.1 0.0 6.6e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KHN69892.1 - 1.1e-15 58.0 0.0 1.8e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Gpi1 PF05024.15 KHN69893.1 - 1.7e-07 31.5 5.9 1.7e-07 31.5 5.9 2.2 1 1 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Cytochrom_B_C PF00032.17 KHN69893.1 - 0.45 10.8 3.4 4 7.8 3.1 2.5 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Orf78 PF06024.12 KHN69893.1 - 1.7 9.0 5.1 1.3 9.3 1.8 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Sec10 PF07393.11 KHN69894.1 - 4.3e-09 35.4 0.4 9.2e-09 34.3 0.4 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec10 Ribosomal_S2 PF00318.20 KHN69895.1 - 3.8e-15 55.7 0.1 1.9e-07 30.6 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 RrnaAD PF00398.20 KHN69896.1 - 7.8e-57 192.3 0.0 9.3e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KHN69896.1 - 2.5e-07 31.3 0.0 8.1e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KHN69896.1 - 1.4e-05 25.7 0.0 2.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KHN69896.1 - 0.00063 20.3 0.0 0.006 17.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KHN69896.1 - 0.00099 18.7 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KHN69896.1 - 0.0029 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KHN69896.1 - 0.0048 16.2 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain PCMT PF01135.19 KHN69896.1 - 0.0054 16.5 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KHN69896.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 KHN69896.1 - 0.043 13.1 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 KHN69896.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 KHN69896.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KHN69896.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 KHN69896.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PQQ_3 PF13570.6 KHN69897.1 - 0.00046 20.6 0.1 0.88 10.1 0.1 3.7 3 0 0 3 3 3 2 PQQ-like domain Kelch_6 PF13964.6 KHN69897.1 - 0.0026 18.0 0.4 0.083 13.2 0.0 3.1 3 0 0 3 3 3 1 Kelch motif ABC_tran PF00005.27 KHN69898.1 - 1.8e-24 86.8 0.0 3.7e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KHN69898.1 - 4.1e-10 39.8 13.6 6.7e-10 39.1 13.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KHN69898.1 - 9.7e-09 35.0 5.0 1.5e-08 34.4 3.1 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KHN69898.1 - 0.00021 21.2 0.0 0.007 16.2 0.2 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KHN69898.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 KHN69898.1 - 0.019 14.7 0.0 0.019 14.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KHN69898.1 - 0.048 14.2 0.2 0.14 12.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN69898.1 - 0.053 13.2 0.3 0.24 11.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KHN69898.1 - 0.075 13.6 0.1 0.33 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Yip1 PF04893.17 KHN69898.1 - 0.42 10.3 5.7 0.45 10.2 0.4 2.5 2 1 0 2 2 2 0 Yip1 domain Tetraspanin PF00335.20 KHN69898.1 - 0.83 9.3 4.5 0.67 9.6 0.4 2.3 2 0 0 2 2 2 0 Tetraspanin family FixH PF05751.11 KHN69898.1 - 9.9 6.2 8.3 0.18 11.8 0.5 2.1 2 0 0 2 2 1 0 FixH PTH2 PF01981.16 KHN69899.1 - 8.2e-12 45.4 0.0 9.5e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2268 PF10026.9 KHN69899.1 - 0.028 14.0 0.2 0.037 13.6 0.2 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF4396 PF14342.6 KHN69899.1 - 0.092 13.1 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Peptidase_M57 PF12388.8 KHN69899.1 - 0.12 11.9 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase HECT PF00632.25 KHN69900.1 - 2.7e-78 263.5 1.2 4.3e-78 262.9 1.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KHN69900.1 - 0.018 15.3 0.1 0.018 15.3 0.1 2.3 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF1122 PF06557.11 KHN69900.1 - 0.083 12.3 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1122) KH_8 PF17903.1 KHN69902.1 - 3.2e-29 100.8 1.0 6.2e-29 99.9 1.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KHN69902.1 - 0.00069 19.4 0.8 0.0084 15.9 0.1 2.6 2 0 0 2 2 2 1 KH domain PCI PF01399.27 KHN69902.1 - 0.09 13.3 0.1 0.29 11.7 0.1 1.8 2 0 0 2 2 2 0 PCI domain UAA PF08449.11 KHN69904.1 - 1.2e-34 119.9 20.4 1.5e-34 119.6 20.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 KHN69904.1 - 0.062 12.6 15.7 1.1 8.5 15.9 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family CRT-like PF08627.10 KHN69904.1 - 0.2 10.5 16.2 0.026 13.5 6.1 2.1 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KHN69904.1 - 1.1 9.5 21.9 0.14 12.3 6.2 3.0 2 1 1 3 3 3 0 EamA-like transporter family Pcc1 PF09341.10 KHN69905.1 - 0.00049 20.2 0.1 0.00073 19.6 0.1 1.3 1 1 0 1 1 1 1 Transcription factor Pcc1 Fcf1 PF04900.12 KHN69906.1 - 1.4e-12 47.9 0.5 2.4e-12 47.1 0.5 1.3 1 0 0 1 1 1 1 Fcf1 tRNA-synt_2 PF00152.20 KHN69907.1 - 4.3e-80 269.1 0.5 5.6e-80 268.8 0.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 KHN69907.1 - 6.6e-10 38.9 0.2 6.9e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 KHN69907.1 - 3.7e-06 26.8 0.2 8e-06 25.8 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peptidase_M24 PF00557.24 KHN69908.1 - 7.9e-44 149.8 0.0 1.4e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 KHN69908.1 - 4.3e-24 85.4 1.4 1.4e-23 83.8 0.0 2.3 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 KHN69908.1 - 7e-11 42.9 0.0 1.5e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 KHN69908.1 - 1.3e-10 41.1 0.0 3e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 zinc-ribbon_6 PF10005.9 KHN69908.1 - 0.31 11.8 0.9 0.55 10.9 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_2 PF13639.6 KHN69909.1 - 9.1e-14 51.5 6.9 9.1e-14 51.5 6.9 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KHN69909.1 - 6.2e-11 42.0 8.0 6.2e-11 42.0 8.0 2.1 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KHN69909.1 - 2.2e-09 36.9 6.0 4.4e-09 35.9 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KHN69909.1 - 4.2e-09 36.6 5.1 4.2e-09 36.6 5.1 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KHN69909.1 - 1e-08 34.9 5.2 1e-08 34.9 5.2 1.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KHN69909.1 - 1.8e-08 34.2 4.1 1.9e-08 34.2 2.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KHN69909.1 - 4.4e-08 33.0 5.2 4.4e-08 33.0 5.2 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KHN69909.1 - 4.3e-07 29.7 2.5 4.3e-07 29.7 2.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KHN69909.1 - 9e-07 28.7 4.5 1.9e-06 27.6 4.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KHN69909.1 - 7.2e-05 22.8 2.2 0.00014 21.9 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KHN69909.1 - 0.012 15.2 4.2 0.012 15.2 4.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KHN69909.1 - 0.016 15.4 8.5 0.38 10.9 8.5 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 KHN69909.1 - 0.057 13.6 6.3 0.46 10.7 6.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KHN69909.1 - 0.16 11.8 4.6 0.35 10.7 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TssO PF17561.2 KHN69909.1 - 0.23 11.5 2.0 16 5.6 0.2 2.5 2 0 0 2 2 2 0 Type VI secretion system, TssO zf-RING_10 PF16685.5 KHN69909.1 - 1.8 8.8 7.1 0.2 11.8 2.8 1.7 2 0 0 2 2 1 0 zinc RING finger of MSL2 RINGv PF12906.7 KHN69909.1 - 8.7 6.6 12.2 0.32 11.2 5.5 2.1 2 1 0 2 2 1 0 RING-variant domain Met_10 PF02475.16 KHN69910.1 - 1.3e-48 165.4 0.0 1.9e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 KHN69910.1 - 1.5e-07 31.4 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.14 KHN69910.1 - 2.5e-05 23.9 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KHN69910.1 - 7.6e-05 23.3 0.0 0.00037 21.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 KHN69910.1 - 0.00019 20.9 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 KHN69910.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 KHN69910.1 - 0.00038 19.5 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 KHN69910.1 - 0.0016 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KHN69910.1 - 0.0019 18.8 0.0 0.016 15.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KHN69910.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 KHN69910.1 - 0.0031 17.1 0.6 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_23 PF13489.6 KHN69910.1 - 0.009 15.9 0.0 0.032 14.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain TRM PF02005.16 KHN69910.1 - 0.014 14.5 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase UQ_con PF00179.26 KHN69911.1 - 5.4e-46 155.7 0.0 6.2e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S17 PF00366.20 KHN69912.1 - 1.7e-22 79.3 2.4 2.9e-22 78.6 2.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KHN69912.1 - 3.6e-18 65.7 0.9 5e-18 65.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Pribosyltran_N PF13793.6 KHN69912.1 - 0.077 12.9 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Lipase_3 PF01764.25 KHN69913.1 - 8e-08 32.3 0.2 2.4e-07 30.7 0.2 1.9 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KHN69913.1 - 2.7e-06 26.8 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 KHN69913.1 - 0.00057 19.1 0.1 0.00087 18.5 0.1 1.3 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 KHN69913.1 - 0.0014 18.3 0.2 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KHN69913.1 - 0.0034 17.0 0.2 0.0079 15.8 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KHN69913.1 - 0.019 15.5 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KHN69913.1 - 0.022 14.4 0.1 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 KHN69913.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 KHN69913.1 - 0.04 13.7 0.3 0.11 12.3 0.0 1.8 3 0 0 3 3 3 0 Alpha/beta hydrolase family Esterase PF00756.20 KHN69913.1 - 0.045 13.4 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Cutinase PF01083.22 KHN69913.1 - 0.047 13.7 0.5 0.11 12.5 0.5 1.6 1 1 0 1 1 1 0 Cutinase Thioesterase PF00975.20 KHN69913.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Ras PF00071.22 KHN69915.1 - 7.5e-53 178.4 0.3 9.3e-53 178.1 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN69915.1 - 4.2e-32 110.9 0.1 7.6e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN69915.1 - 1.7e-16 60.1 0.1 2.3e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KHN69915.1 - 3.9e-06 26.9 0.1 6.1e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KHN69915.1 - 3.5e-05 23.3 0.0 6.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KHN69915.1 - 4.4e-05 23.1 0.3 0.0023 17.5 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KHN69915.1 - 0.00016 21.6 0.1 0.37 10.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 KHN69915.1 - 0.0012 18.2 0.1 0.0018 17.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KHN69915.1 - 0.018 14.8 0.0 0.048 13.4 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KHN69915.1 - 0.035 13.8 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 KHN69915.1 - 0.039 13.7 0.1 0.068 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN69915.1 - 0.077 13.3 0.0 0.69 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KHN69915.1 - 0.078 12.8 0.4 0.33 10.7 0.4 1.9 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system VPS13_C PF16909.5 KHN69916.1 - 2.1e-24 86.3 7.5 7.8e-20 71.4 1.1 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KHN69916.1 - 2.8e-19 69.3 0.1 9.7e-19 67.6 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 KHN69916.1 - 0.13 11.6 0.0 9.4 5.5 0.0 3.0 3 0 0 3 3 3 0 SHR-binding domain of vacuolar-sorting associated protein 13 Metallophos PF00149.28 KHN69917.1 - 8.3e-39 134.2 0.1 1e-38 133.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KHN69917.1 - 0.0032 17.9 0.3 0.008 16.6 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Rhodanese PF00581.20 KHN69918.1 - 5.9e-11 42.8 0.0 1.3e-10 41.7 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain PTH2 PF01981.16 KHN69919.1 - 4e-30 104.5 0.0 4.9e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glucosamine_iso PF01182.20 KHN69920.1 - 4.9e-23 82.2 0.0 6.4e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L22e PF01776.17 KHN69921.1 - 1.7e-22 79.8 0.1 1.9e-22 79.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family ANAPC2 PF08672.11 KHN69921.1 - 0.072 13.6 0.0 5.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 tRNA-synt_2b PF00587.25 KHN69922.1 - 1.4e-32 113.1 0.4 3.5e-32 111.8 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KHN69922.1 - 1.3e-16 60.7 5.7 2.4e-16 59.9 5.7 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 KHN69922.1 - 0.084 12.2 2.9 0.16 11.3 2.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding tRNA-synt_His PF13393.6 KHN69922.1 - 0.11 11.8 0.3 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Laminin_I PF06008.14 KHN69922.1 - 0.12 12.0 0.6 1.2 8.8 0.6 2.0 1 1 0 1 1 1 0 Laminin Domain I PROCN PF08083.11 KHN69923.1 - 1.5e-93 313.8 12.1 2.2e-88 296.7 5.0 2.4 2 0 0 2 2 2 2 PROCN (NUC071) domain U6-snRNA_bdg PF10596.9 KHN69923.1 - 1.8e-66 223.0 1.2 3.5e-66 222.1 1.2 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 KHN69923.1 - 4.7e-33 114.1 0.1 3e-32 111.5 0.0 2.5 3 0 0 3 3 3 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.11 KHN69923.1 - 7.4e-31 107.1 0.5 2.2e-30 105.6 0.1 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 KHN69923.1 - 2.6e-22 79.0 0.6 8.3e-22 77.3 0.6 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PRP8_domainIV PF12134.8 KHN69923.1 - 1.3e-16 60.9 0.0 2.6e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 PRP8 domain IV core PROCT PF08084.11 KHN69923.1 - 4.8e-07 29.7 1.0 1.2e-06 28.4 0.3 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain Sec-ASP3 PF15432.6 KHN69923.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 eIF-6 PF01912.18 KHN69925.1 - 1.1e-74 250.2 1.4 1.3e-74 249.8 1.4 1.1 1 0 0 1 1 1 1 eIF-6 family LSM PF01423.22 KHN69926.1 - 2.6e-16 59.1 0.3 3e-16 58.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KHN69926.1 - 0.004 17.3 0.0 0.0079 16.3 0.0 1.5 1 1 1 2 2 2 1 Ataxin 2 SM domain EMP24_GP25L PF01105.24 KHN69927.1 - 0.037 14.0 0.6 0.065 13.2 0.6 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1654 PF07867.11 KHN69927.1 - 0.1 12.4 0.1 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) EF-hand_7 PF13499.6 KHN69928.1 - 1e-10 41.9 0.3 8.3e-09 35.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KHN69928.1 - 1.8e-09 36.5 1.4 3.1e-06 26.3 0.0 4.5 4 1 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 KHN69928.1 - 3.4e-09 35.9 0.6 0.0007 19.3 0.0 4.4 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 KHN69928.1 - 5.4e-08 32.6 0.3 5.1e-06 26.2 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 KHN69928.1 - 1.6e-05 24.2 0.0 0.00023 20.5 0.0 2.9 3 0 0 3 3 3 1 EF hand Caleosin PF05042.13 KHN69928.1 - 0.024 14.6 0.4 10 6.0 0.0 2.7 3 0 0 3 3 3 0 Caleosin related protein RE_R_Pab1 PF09522.10 KHN69928.1 - 0.034 14.2 0.2 0.048 13.8 0.2 1.2 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease SPARC_Ca_bdg PF10591.9 KHN69928.1 - 0.091 13.1 0.0 0.26 11.6 0.0 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region CbiG_C PF01890.16 KHN69928.1 - 0.2 12.2 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus Nop PF01798.18 KHN69929.1 - 3.2e-70 236.2 1.0 4.3e-70 235.8 1.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KHN69929.1 - 0.0071 16.7 0.5 0.55 10.6 0.2 3.2 2 1 1 3 3 3 1 NOP5NT (NUC127) domain DUF1151 PF06625.11 KHN69929.1 - 0.011 15.7 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) PAXNEB PF05625.11 KHN69930.1 - 6.8e-23 81.4 0.3 1.3e-09 37.7 0.0 3.9 1 1 1 2 2 2 2 PAXNEB protein Asn_synthase PF00733.21 KHN69931.1 - 1.1e-26 94.4 0.0 1.7e-12 47.7 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase ATP_bind_3 PF01171.20 KHN69931.1 - 0.0012 18.6 0.1 0.005 16.6 0.0 2.0 2 0 0 2 2 2 1 PP-loop family MCM PF00493.23 KHN69932.1 - 2.1e-95 318.1 0.0 3.6e-95 317.3 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN69932.1 - 3.1e-37 127.2 0.0 5.8e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KHN69932.1 - 9.8e-27 93.2 0.9 1.9e-26 92.3 0.1 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KHN69932.1 - 5.9e-13 49.3 0.1 1.4e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KHN69932.1 - 8.4e-10 38.4 0.3 6.8e-08 32.1 0.1 2.9 2 2 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KHN69932.1 - 7.3e-05 22.8 0.0 0.00022 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KHN69932.1 - 0.0019 18.1 0.0 0.0062 16.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KHN69932.1 - 0.0089 15.8 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 KHN69932.1 - 0.12 12.2 0.1 0.83 9.4 0.1 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cnd1 PF12717.7 KHN69934.1 - 0.06 13.4 0.3 0.06 13.4 0.3 2.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Diedel PF13164.6 KHN69935.1 - 0.0071 16.8 1.0 1.5 9.3 0.1 3.1 3 0 0 3 3 3 2 Diedel PseudoU_synth_1 PF01416.20 KHN69936.1 - 6.2e-15 55.6 0.0 1.9e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase tRNA_synthFbeta PF17759.1 KHN69937.1 - 3.2e-35 121.5 0.0 6.7e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KHN69937.1 - 3.6e-24 84.8 0.5 1.1e-23 83.3 0.5 1.9 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 KHN69937.1 - 3.8e-18 65.6 0.5 2.6e-13 50.1 0.2 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 KHN69937.1 - 6.7e-17 61.7 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain DSHCT PF08148.12 KHN69938.1 - 2.2e-42 144.5 0.0 4.2e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KHN69938.1 - 1.5e-16 60.7 0.0 3.3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69938.1 - 2e-07 31.4 0.0 9.3e-07 29.2 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69938.1 - 2e-05 24.7 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 KHN69938.1 - 0.00089 19.3 0.1 0.00089 19.3 0.1 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain DUF4277 PF14104.6 KHN69938.1 - 0.0081 16.5 0.2 0.039 14.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4277) ATPase_2 PF01637.18 KHN69938.1 - 0.03 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KHN69938.1 - 0.042 12.9 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 KHN69938.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TMEM65 PF10507.9 KHN69939.1 - 0.088 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 65 SMC_N PF02463.19 KHN69940.1 - 7.8e-53 179.1 0.0 1.2e-52 178.5 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KHN69940.1 - 1.1e-22 80.6 0.0 3.1e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KHN69940.1 - 4.1e-16 59.7 0.1 7.9e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KHN69940.1 - 3.6e-11 43.9 11.7 3.6e-11 43.9 11.7 5.9 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 KHN69940.1 - 1.7e-06 27.6 0.0 3.6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KHN69940.1 - 3.8e-06 26.9 21.3 3.8e-06 26.9 21.3 4.4 2 2 0 2 2 2 1 AAA ATPase domain FliD_N PF02465.18 KHN69940.1 - 0.24 12.1 3.6 9.3 7.0 0.3 3.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Cas_CXXC_CXXC PF09706.10 KHN69940.1 - 0.53 10.5 5.8 6.5 7.1 0.5 3.9 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) AAA_22 PF13401.6 KHN69940.1 - 0.96 9.7 7.6 9.3 6.5 0.0 3.8 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 KHN69940.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.5 5 2 0 5 5 5 0 ABC transporter Sec66 PF09802.9 KHN69941.1 - 5.7e-08 32.5 1.6 1.1e-07 31.7 1.6 1.5 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 TFIID-18kDa PF02269.16 KHN69942.1 - 3.1e-20 72.0 0.2 3.6e-20 71.8 0.2 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Homeodomain PF00046.29 KHN69944.1 - 1.5e-14 53.6 2.0 2.5e-14 52.8 2.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KHN69944.1 - 2e-06 27.6 0.5 4.2e-06 26.6 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Ntox6 PF15544.6 KHN69944.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 6 SRP54 PF00448.22 KHN69945.1 - 1.3e-68 230.5 0.3 2e-68 229.9 0.3 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KHN69945.1 - 5.2e-26 91.2 2.0 3.7e-25 88.4 0.0 2.9 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 KHN69945.1 - 9.3e-13 48.2 0.3 3e-12 46.6 0.3 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KHN69945.1 - 6.3e-07 29.1 0.3 5.4e-06 26.1 0.3 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KHN69945.1 - 0.00078 18.5 0.1 0.0026 16.8 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KHN69945.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 KHN69945.1 - 0.003 17.4 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 KHN69945.1 - 0.0099 16.0 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KHN69945.1 - 0.027 13.9 0.4 17 4.8 0.0 3.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KHN69945.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 KHN69945.1 - 0.03 14.2 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase POTRA_2 PF08479.11 KHN69945.1 - 0.036 13.9 0.1 4.1 7.3 0.1 3.6 4 0 0 4 4 4 0 POTRA domain, ShlB-type CbiA PF01656.23 KHN69945.1 - 0.06 13.4 0.0 0.31 11.1 0.0 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 KHN69945.1 - 0.068 13.4 0.0 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain LacI PF00356.21 KHN69945.1 - 0.093 12.5 0.4 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family MMR_HSR1 PF01926.23 KHN69945.1 - 0.095 12.8 0.1 0.7 10.0 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_8 PF12780.7 KHN69945.1 - 0.1 11.9 0.4 14 4.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KHN69945.1 - 0.1 12.1 0.0 0.32 10.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Myosin_head PF00063.21 KHN69947.1 - 7.2e-250 830.9 6.1 7.2e-250 830.9 6.1 2.4 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.19 KHN69947.1 - 0.00025 20.8 2.0 0.0006 19.6 2.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain KNOX2 PF03791.13 KHN69947.1 - 0.005 16.3 0.0 0.028 13.9 0.0 2.3 1 0 0 1 1 1 1 KNOX2 domain AAA_22 PF13401.6 KHN69947.1 - 0.034 14.4 7.4 0.06 13.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain XPC-binding PF09280.11 KHN69947.1 - 0.039 13.7 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 XPC-binding domain AAA_16 PF13191.6 KHN69947.1 - 0.048 14.0 0.0 0.27 11.6 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain ETF_QO PF05187.13 KHN69947.1 - 3.8 7.7 4.9 14 5.8 0.5 3.0 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Ribosomal_L29e PF01779.17 KHN69948.1 - 8.1e-15 54.9 5.0 9.8e-15 54.6 5.0 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Caps_synth PF05704.12 KHN69949.1 - 0.024 14.0 0.2 0.028 13.8 0.2 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribosomal_S27e PF01667.17 KHN69950.1 - 2.7e-11 43.0 3.9 4.5e-11 42.3 3.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_5 PF13719.6 KHN69950.1 - 1.1 9.1 5.6 33 4.3 5.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_12 PF11331.8 KHN69950.1 - 4.4 7.2 8.5 2.7 7.9 0.3 2.5 2 1 1 3 3 3 0 Probable zinc-ribbon domain Cpn60_TCP1 PF00118.24 KHN69951.1 - 4.5e-58 197.1 6.6 1.5e-56 192.1 4.8 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Homeodomain PF00046.29 KHN69952.1 - 2.4e-17 62.5 0.6 3.5e-17 62.0 0.6 1.3 1 0 0 1 1 1 1 Homeodomain RNA_pol_I_A49 PF06870.12 KHN69953.1 - 0.001 18.0 0.1 0.75 8.6 0.0 2.1 1 1 1 2 2 2 2 A49-like RNA polymerase I associated factor DUF730 PF05325.11 KHN69953.1 - 0.055 13.5 1.0 0.45 10.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Glycos_transf_2 PF00535.26 KHN69955.1 - 1.7e-26 93.1 0.0 2.2e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KHN69955.1 - 4.5e-14 52.9 0.0 5.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KHN69955.1 - 8.2e-05 22.2 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KHN69955.1 - 0.0051 16.3 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Topoisom_bac PF01131.20 KHN69956.1 - 1.4e-108 363.5 0.0 1.9e-108 363.1 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 KHN69956.1 - 7.4e-18 64.4 22.0 2.1e-09 37.3 4.9 3.0 3 0 0 3 3 3 2 GRF zinc finger Toprim PF01751.22 KHN69956.1 - 9.6e-18 64.3 0.0 2.3e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Cullin_Nedd8 PF10557.9 KHN69956.1 - 0.0085 16.1 0.3 2.9 8.0 0.0 3.3 3 0 0 3 3 3 1 Cullin protein neddylation domain NHase_alpha PF02979.16 KHN69957.1 - 0.021 14.2 0.0 0.034 13.4 0.0 1.4 1 1 0 1 1 1 0 Nitrile hydratase, alpha chain TNFR_16_TM PF18422.1 KHN69957.1 - 0.11 12.5 3.4 0.2 11.6 3.4 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF1764 PF08576.10 KHN69957.1 - 0.46 11.4 4.0 0.47 11.4 3.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Actin PF00022.19 KHN69958.1 - 3.7e-32 111.4 1.1 5.1e-27 94.5 0.2 3.2 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 KHN69958.1 - 0.0045 15.9 5.4 0.029 13.2 5.4 2.1 1 1 0 1 1 1 1 MreB/Mbl protein GTP_EFTU PF00009.27 KHN69959.1 - 2.6e-40 138.1 0.2 3.7e-40 137.6 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KHN69959.1 - 8.2e-12 45.4 0.1 2.8e-11 43.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KHN69959.1 - 5.4e-09 36.3 0.9 1.5e-08 34.9 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KHN69959.1 - 0.00074 19.6 0.3 0.011 15.8 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KHN69959.1 - 0.0048 16.1 0.1 0.0081 15.4 0.1 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Septin PF00735.18 KHN69959.1 - 0.027 13.8 0.2 0.056 12.7 0.2 1.5 1 0 0 1 1 1 0 Septin Gtr1_RagA PF04670.12 KHN69959.1 - 0.075 12.4 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SMC_N PF02463.19 KHN69959.1 - 0.11 11.9 0.2 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TP6A_N PF04406.14 KHN69960.1 - 1.1e-09 38.1 0.0 3.5e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 KHN69960.1 - 0.0014 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF3909 PF13077.6 KHN69961.1 - 0.081 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) B2 PF11473.8 KHN69961.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 RNA binding protein B2 Glyco_transf_15 PF01793.16 KHN69962.1 - 9.3e-110 366.9 12.5 1.2e-109 366.5 12.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Cir_N PF10197.9 KHN69962.1 - 0.079 13.2 2.3 0.32 11.2 1.9 2.0 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Rota_VP4_MID PF17477.2 KHN69962.1 - 0.11 11.8 1.9 0.19 11.1 1.1 1.7 1 1 1 2 2 2 0 Rotavirus VP4 membrane interaction domain tRNA-synt_1 PF00133.22 KHN69963.1 - 2.7e-185 617.1 0.0 1.4e-184 614.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KHN69963.1 - 1.4e-23 83.5 0.3 2.8e-23 82.6 0.3 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KHN69963.1 - 2e-17 63.1 0.4 1e-09 37.6 0.0 4.8 4 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KHN69963.1 - 6.6e-10 38.8 0.2 8.2e-09 35.2 0.0 2.5 3 0 0 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KHN69963.1 - 0.00088 18.7 0.0 0.31 10.3 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 KHN69963.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) PPP5 PF08321.12 KHN69963.1 - 0.029 14.6 0.6 0.071 13.4 0.6 1.6 1 0 0 1 1 1 0 PPP5 TPR repeat region tRNA-synt_1b PF00579.25 KHN69963.1 - 0.051 12.9 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UPF0121 PF03661.13 KHN69964.1 - 8.9e-10 38.4 7.8 8.9e-10 38.4 7.8 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF3959 PF13105.6 KHN69964.1 - 0.12 11.9 3.5 0.097 12.2 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Transket_pyr PF02779.24 KHN69965.1 - 1.2e-38 132.6 0.0 1.5e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KHN69965.1 - 1e-34 119.1 0.1 5.8e-34 116.6 0.1 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KHN69965.1 - 0.00036 20.8 0.0 0.00086 19.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II eIF-1a PF01176.19 KHN69966.1 - 2.5e-13 49.6 0.1 4.3e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Aa_trans PF01490.18 KHN69967.1 - 4.1e-35 121.3 41.3 5.7e-35 120.8 41.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SWIB PF02201.18 KHN69968.1 - 7.7e-13 48.1 0.3 3.3e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain Ufd2P_core PF10408.9 KHN69969.1 - 1.7e-45 155.8 13.5 4.1e-31 108.3 5.1 3.3 1 1 1 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 KHN69969.1 - 2.8e-13 49.9 0.3 6.1e-13 48.7 0.3 1.5 1 0 0 1 1 1 1 U-box domain FlxA PF14282.6 KHN69969.1 - 0.039 13.9 3.3 0.065 13.2 3.3 1.3 1 0 0 1 1 1 0 FlxA-like protein CAMP_factor PF07373.11 KHN69969.1 - 0.048 13.3 0.6 0.11 12.0 0.6 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) Katanin_con80 PF13925.6 KHN69969.1 - 0.077 13.0 0.1 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 con80 domain of Katanin Phage_GP20 PF06810.11 KHN69969.1 - 0.094 12.5 3.1 0.76 9.6 2.0 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF724 PF05266.14 KHN69969.1 - 0.22 11.3 5.1 1.4 8.7 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 KHN69969.1 - 0.35 10.7 3.3 0.86 9.4 3.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Thymidylate_kin PF02223.17 KHN69970.1 - 1.1e-38 132.8 0.1 1.3e-38 132.5 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KHN69970.1 - 1.1e-06 29.0 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KHN69970.1 - 0.00075 19.4 0.2 0.027 14.3 0.2 2.3 1 1 0 1 1 1 1 Deoxynucleoside kinase KTI12 PF08433.10 KHN69970.1 - 0.004 16.6 0.0 0.009 15.5 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KHN69970.1 - 0.011 16.3 0.1 0.033 14.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KHN69970.1 - 0.022 14.8 0.3 1.3 9.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arf PF00025.21 KHN69970.1 - 0.022 14.2 0.2 0.062 12.8 0.0 1.9 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_16 PF13191.6 KHN69970.1 - 0.075 13.4 0.0 0.085 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain MIP-T3 PF10243.9 KHN69970.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain AAA_33 PF13671.6 KHN69970.1 - 0.13 12.4 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain HUN PF08729.10 KHN69971.1 - 1.2e-09 38.1 0.1 4.1e-09 36.3 0.1 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain YafO_toxin PF13957.6 KHN69971.1 - 0.12 12.4 3.1 1.4 9.0 0.1 2.7 2 1 0 2 2 2 0 Toxin YafO, type II toxin-antitoxin system LMBR1 PF04791.16 KHN69971.1 - 5.7 5.7 5.1 7.7 5.3 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Brix PF04427.18 KHN69972.1 - 1.7e-06 28.3 0.5 3.5e-06 27.3 0.5 1.5 1 1 0 1 1 1 1 Brix domain WD40 PF00400.32 KHN69973.1 - 2.8e-23 81.7 12.3 2.7e-07 31.2 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN69973.1 - 1.4e-13 50.9 2.9 9.1e-05 22.7 0.1 4.6 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KHN69973.1 - 1.3e-06 27.6 0.0 0.0013 17.8 0.0 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KHN69973.1 - 0.00079 19.4 1.1 1.3 8.8 0.1 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Curlin_rpt PF07012.12 KHN69973.1 - 0.0013 18.7 0.3 0.0031 17.5 0.3 1.6 1 0 0 1 1 1 1 Curlin associated repeat Nbas_N PF15492.6 KHN69973.1 - 0.041 13.2 0.7 0.33 10.2 0.2 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SAC3_GANP PF03399.16 KHN69974.1 - 7.8e-39 133.8 0.4 1.2e-38 133.2 0.4 1.3 1 0 0 1 1 1 1 SAC3/GANP family Acyltransferase PF01553.21 KHN69976.1 - 2e-09 37.2 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KHN69976.1 - 0.03 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase C-terminus DUF2955 PF11168.8 KHN69976.1 - 0.46 10.3 5.2 8.7 6.2 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) DSHCT PF08148.12 KHN69977.1 - 7.2e-41 139.6 0.2 2.2e-40 138.0 0.0 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KHN69977.1 - 2.1e-18 66.7 0.0 4.3e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN69977.1 - 3e-06 27.6 0.0 1.4e-05 25.3 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN69977.1 - 2.4e-05 24.4 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RRM_1 PF00076.22 KHN69978.1 - 3.1e-14 52.5 0.4 6.3e-06 25.9 0.1 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.22 KHN69978.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain SspH PF08141.12 KHN69978.1 - 0.061 13.5 0.1 5.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Small acid-soluble spore protein H family Ribosomal_L32e PF01655.18 KHN69979.1 - 9.8e-40 135.3 0.2 1.2e-39 135.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 MMS1_N PF10433.9 KHN69980.1 - 0.064 11.9 1.4 0.26 9.9 0.2 2.2 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PSRP-3_Ycf65 PF04839.13 KHN69982.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) VSP PF03302.13 KHN69983.1 - 0.21 10.4 1.6 0.29 10.0 1.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein S10_plectin PF03501.15 KHN69984.1 - 1.1e-16 60.7 0.1 1.2e-16 60.6 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Baculo_11_kDa PF06143.11 KHN69985.1 - 0.039 13.5 0.0 0.067 12.8 0.0 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Rad21_Rec8_N PF04825.13 KHN69986.1 - 4.3e-05 23.6 0.1 7.8e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KHN69986.1 - 0.00065 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Ribosomal_L13 PF00572.18 KHN69987.1 - 0.00035 20.8 1.5 0.084 13.1 0.9 2.6 1 1 0 1 1 1 1 Ribosomal protein L13 DUF2812 PF11193.8 KHN69987.1 - 0.048 13.9 0.8 0.075 13.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) YL1_C PF08265.11 KHN69988.1 - 9.5e-12 44.5 2.4 1.7e-11 43.7 2.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RNA_pol_Rpb1_5 PF04998.17 KHN69989.1 - 2.9e-81 272.8 0.1 9.1e-81 271.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KHN69989.1 - 2.6e-61 206.7 0.4 4.9e-61 205.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KHN69989.1 - 1.4e-33 116.0 3.5 2.3e-33 115.4 0.4 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KHN69989.1 - 2.9e-32 112.2 0.0 7e-32 111.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KHN69989.1 - 1.5e-19 69.9 0.0 1.5e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Raftlin PF15250.6 KHN69989.1 - 0.47 9.1 3.4 0.86 8.3 3.4 1.3 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 KHN69989.1 - 0.48 8.6 11.8 0.68 8.1 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KHN69989.1 - 2.8 6.1 6.5 4.1 5.6 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein R_equi_Vir PF05526.11 KHN69990.1 - 0.12 12.2 1.1 0.45 10.4 0.9 2.0 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein ATPgrasp_TupA PF14305.6 KHN69991.1 - 0.0013 18.6 4.5 0.0023 17.8 4.5 1.3 1 0 0 1 1 1 1 TupA-like ATPgrasp DUF272 PF03312.15 KHN69991.1 - 0.087 13.1 2.4 0.11 12.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF272) Condensin2nSMC PF12422.8 KHN69991.1 - 0.15 12.3 0.7 0.26 11.5 0.7 1.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit HATPase_c_5 PF14501.6 KHN69991.1 - 0.16 11.9 3.4 7.2 6.6 0.1 2.5 2 0 0 2 2 2 0 GHKL domain Skp1_POZ PF03931.15 KHN69992.1 - 2.3e-05 24.5 1.2 0.0009 19.4 0.1 2.3 2 1 0 2 2 2 2 Skp1 family, tetramerisation domain zf-RING_UBOX PF13445.6 KHN69993.1 - 0.002 18.1 2.4 0.0048 16.9 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 KHN69993.1 - 0.07 12.9 1.3 0.15 11.8 1.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 KHN69993.1 - 0.086 13.0 5.0 0.22 11.7 5.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KHN69993.1 - 0.37 10.8 2.7 1.2 9.2 2.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KHN69993.1 - 0.39 11.1 3.3 1.3 9.5 3.3 1.9 1 0 0 1 1 1 0 Ring finger domain RyR PF02026.16 KHN69994.1 - 0.019 15.1 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 RyR domain TBP PF00352.21 KHN69995.1 - 1.2e-65 217.5 0.8 1.4e-31 108.3 0.2 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KHN69995.1 - 5.8e-06 26.3 0.1 0.025 14.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KHN69995.1 - 0.084 12.7 0.3 0.66 9.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DENN PF02141.21 KHN69997.1 - 1.8e-09 37.8 0.9 4.5e-09 36.5 0.9 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF321 PF03778.13 KHN69997.1 - 1.6 8.4 3.8 6.4 6.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Na_H_Exchanger PF00999.21 KHN69998.1 - 1.6e-34 119.4 36.4 2e-34 119.0 36.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-ZPR1 PF03367.13 KHN69999.1 - 5.9e-16 58.7 5.7 7.2e-16 58.4 5.7 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain LisH PF08513.11 KHN70000.1 - 7.5e-10 38.4 0.3 1.6e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 LisH LisH_2 PF16045.5 KHN70000.1 - 0.021 13.8 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 LisH UFD1 PF03152.14 KHN70000.1 - 0.034 13.6 0.1 5.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin fusion degradation protein UFD1 RCC1 PF00415.18 KHN70001.1 - 2.3e-54 181.8 3.8 1.1e-09 38.8 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KHN70001.1 - 2.6e-25 87.6 34.3 5e-06 26.2 0.3 7.3 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat tRNA_bind PF01588.20 KHN70002.1 - 7.9e-19 67.6 0.1 2.1e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain MDD_C PF18376.1 KHN70002.1 - 0.075 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain RabGAP-TBC PF00566.18 KHN70004.1 - 6.8e-33 114.1 2.4 9.8e-33 113.6 2.4 1.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HSBP1 PF06825.12 KHN70004.1 - 1 9.3 3.3 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 FTR1 PF03239.14 KHN70005.1 - 0.041 13.0 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family IL5 PF02025.15 KHN70005.1 - 0.075 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Interleukin 5 mRNA_triPase PF02940.15 KHN70006.1 - 1.7e-21 77.0 6.4 3.4e-11 43.3 4.8 2.0 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain RP853 PF17542.2 KHN70006.1 - 0.042 13.0 2.6 0.059 12.5 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 Peptidase_M32 PF02074.15 KHN70006.1 - 0.054 12.3 0.4 0.062 12.1 0.4 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Ras PF00071.22 KHN70007.1 - 1.9e-42 144.7 0.1 2.2e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN70007.1 - 7.9e-30 103.5 0.0 1.2e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN70007.1 - 1.9e-10 40.5 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KHN70007.1 - 1.6e-08 34.2 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KHN70007.1 - 5.8e-08 32.8 0.0 9.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KHN70007.1 - 6.3e-06 26.2 0.0 0.092 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KHN70007.1 - 2.3e-05 24.0 0.2 0.00037 20.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KHN70007.1 - 0.0005 19.9 0.1 0.48 10.2 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein G-alpha PF00503.20 KHN70007.1 - 0.0076 15.5 0.3 6.7 5.8 0.0 3.0 2 1 1 3 3 3 1 G-protein alpha subunit AAA_24 PF13479.6 KHN70007.1 - 0.031 14.0 0.0 0.096 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KHN70007.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KHN70007.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 1 0 1 1 1 0 NTPase RNA_helicase PF00910.22 KHN70007.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 KHN70007.1 - 0.16 11.5 0.2 1.2 8.7 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 KHN70007.1 - 0.21 11.5 0.0 0.52 10.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain DUF4263 PF14082.6 KHN70008.1 - 0.077 13.2 0.2 0.091 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) WD40 PF00400.32 KHN70009.1 - 5.7e-05 23.8 0.1 2 9.4 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat amfpi-1 PF12190.8 KHN70009.1 - 0.14 12.7 0.2 0.59 10.8 0.1 1.9 2 0 0 2 2 2 0 Fungal protease inhibitor HSR PF03172.13 KHN70010.1 - 0.037 14.2 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 HSR domain TBCA PF02970.16 KHN70011.1 - 3.6e-05 24.0 2.2 4.5e-05 23.7 2.2 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Suppressor_APC PF11414.8 KHN70011.1 - 0.0035 17.4 0.1 0.0045 17.0 0.1 1.2 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein SPATA24 PF15175.6 KHN70011.1 - 0.0095 15.8 3.3 0.012 15.6 3.3 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 MIF4G PF02854.19 KHN70012.1 - 4e-17 62.6 6.4 1.3e-16 60.9 6.4 1.8 1 0 0 1 1 1 1 MIF4G domain SpoVT_C PF15714.5 KHN70012.1 - 0.035 14.1 0.5 0.13 12.3 0.5 2.0 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor MA3 PF02847.17 KHN70012.1 - 0.93 9.5 4.9 0.57 10.2 0.1 2.9 3 0 0 3 3 3 0 MA3 domain CLTH PF10607.9 KHN70013.1 - 0.0046 16.9 0.4 0.011 15.6 0.3 1.8 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF2220 PF09983.9 KHN70013.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) FAM176 PF14851.6 KHN70014.1 - 0.029 14.0 1.9 0.031 13.9 1.9 1.0 1 0 0 1 1 1 0 FAM176 family Cir_N PF10197.9 KHN70014.1 - 0.048 13.9 9.2 0.56 10.5 9.2 2.1 1 1 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR UCH_C PF18031.1 KHN70014.1 - 0.12 12.3 6.3 0.17 11.8 6.3 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases Chs7 PF12271.8 KHN70016.1 - 3.4e-22 79.1 23.2 7e-22 78.1 23.2 1.4 1 1 0 1 1 1 1 Chitin synthase export chaperone ABC_tran PF00005.27 KHN70017.1 - 2.4e-29 102.6 0.0 5.2e-29 101.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 KHN70017.1 - 4.2e-19 69.3 5.7 6.2e-19 68.7 5.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KHN70017.1 - 4.1e-07 29.7 1.9 3.8e-05 23.2 1.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 KHN70017.1 - 0.00037 20.5 0.1 0.0062 16.5 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_29 PF13555.6 KHN70017.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KHN70017.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KHN70017.1 - 0.0015 18.8 0.0 0.011 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KHN70017.1 - 0.0027 18.2 0.1 0.0067 17.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KHN70017.1 - 0.0048 16.8 0.2 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KHN70017.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KHN70017.1 - 0.0063 16.9 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KHN70017.1 - 0.0068 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 KHN70017.1 - 0.0085 16.4 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KHN70017.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KHN70017.1 - 0.014 15.2 0.2 0.21 11.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 KHN70017.1 - 0.017 14.8 1.3 0.04 13.6 0.0 2.2 2 2 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KHN70017.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KHN70017.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 KHN70017.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KHN70017.1 - 0.11 12.9 0.1 0.76 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 KHN70017.1 - 0.11 11.4 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KHN70017.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KHN70017.1 - 0.16 11.7 0.4 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KHN70017.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Ribosomal_L31e PF01198.19 KHN70018.1 - 7.5e-13 48.5 0.5 9e-13 48.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Glyco_hydro_5_C PF18564.1 KHN70018.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.3 1 1 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain Cpn60_TCP1 PF00118.24 KHN70019.1 - 1.8e-147 491.9 10.1 2e-147 491.8 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Amj PF10997.8 KHN70019.1 - 0.14 11.4 0.9 0.42 9.9 0.2 2.0 2 0 0 2 2 2 0 Alternate to MurJ PSP1 PF04468.12 KHN70020.1 - 8.5e-29 99.7 1.1 8.5e-29 99.7 1.1 1.9 2 1 0 2 2 2 1 PSP1 C-terminal conserved region DUF3885 PF13021.6 KHN70020.1 - 0.11 12.6 0.1 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) TatD_DNase PF01026.21 KHN70021.1 - 8e-50 169.6 0.0 9.6e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CENP-C_C PF11699.8 KHN70022.1 - 2.2e-05 24.5 0.6 3.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 KHN70022.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Chromo PF00385.24 KHN70023.1 - 3.2e-18 65.4 2.6 1.3e-16 60.2 1.2 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KHN70023.1 - 9e-11 41.7 0.1 7.4e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Spt20 PF12090.8 KHN70023.1 - 0.01 15.5 10.0 0.012 15.2 10.0 1.1 1 0 0 1 1 1 0 Spt20 family Phage_lysozyme PF00959.19 KHN70023.1 - 0.014 15.9 2.7 0.04 14.4 0.1 2.4 2 1 0 2 2 2 0 Phage lysozyme Gti1_Pac2 PF09729.9 KHN70023.1 - 0.12 12.4 10.1 0.16 12.0 10.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TraV PF09676.10 KHN70023.1 - 0.18 12.8 7.9 0.34 11.9 7.9 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) CDC45 PF02724.14 KHN70023.1 - 0.3 9.3 6.9 0.33 9.2 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2981 PF11200.8 KHN70023.1 - 0.5 10.1 5.2 0.6 9.8 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SLC12 PF03522.15 KHN70023.1 - 1.3 8.0 10.3 1.6 7.7 10.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 KHN70023.1 - 1.5 7.9 2.8 1.5 7.9 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 KHN70023.1 - 3 7.8 8.9 4.1 7.4 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 KHN70023.1 - 5.2 5.6 5.8 5.9 5.5 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KHN70023.1 - 5.5 5.7 12.0 6.5 5.4 12.0 1.1 1 0 0 1 1 1 0 Presenilin Mg_trans_NIPA PF05653.14 KHN70024.1 - 2.6e-31 108.9 22.6 2.7e-22 79.2 8.1 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KHN70024.1 - 0.0073 16.5 2.6 0.0073 16.5 2.6 3.4 3 1 0 3 3 3 1 EamA-like transporter family Pox_A14 PF05767.12 KHN70024.1 - 8.5 6.6 11.4 2.6 8.2 1.4 3.6 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Exonuc_VII_L PF02601.15 KHN70025.1 - 0.0031 17.1 7.3 0.0044 16.6 7.3 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Nup54 PF13874.6 KHN70025.1 - 0.0054 16.8 4.1 0.0054 16.8 4.1 2.2 1 1 0 2 2 2 1 Nucleoporin complex subunit 54 ALIX_LYPXL_bnd PF13949.6 KHN70025.1 - 0.027 13.8 12.3 0.34 10.2 2.8 2.3 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DUF725 PF05267.12 KHN70025.1 - 0.1 12.6 2.5 0.18 11.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF725) NPV_P10 PF05531.12 KHN70025.1 - 0.15 12.5 2.6 0.22 12.0 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 KHN70025.1 - 0.23 11.6 17.6 0.92 9.7 6.2 2.3 1 1 1 2 2 2 0 Tropomyosin like Yuri_gagarin PF15934.5 KHN70025.1 - 0.24 11.2 14.9 0.094 12.5 11.3 1.9 1 1 1 2 2 2 0 Yuri gagarin GPS2_interact PF15784.5 KHN70025.1 - 0.85 10.1 7.8 0.23 11.9 3.6 2.2 1 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF2203 PF09969.9 KHN70025.1 - 1.6 9.5 10.4 1.1 10.0 1.9 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FTA4 PF13093.6 KHN70025.1 - 1.6 8.5 11.5 2 8.3 11.5 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BLOC1_2 PF10046.9 KHN70025.1 - 1.9 8.8 12.1 0.17 12.2 1.0 3.3 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 KHN70025.1 - 2.3 7.5 6.7 3.3 7.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 KHN70025.1 - 3.2 6.9 13.2 3.8 6.7 5.7 2.2 1 1 1 2 2 2 0 TMPIT-like protein PspB PF06667.12 KHN70025.1 - 3.2 7.9 7.9 0.43 10.7 1.1 2.5 2 0 0 2 2 2 0 Phage shock protein B Ead_Ea22 PF13935.6 KHN70025.1 - 3.7 8.2 8.8 8.1 7.1 8.0 1.8 1 1 1 2 2 2 0 Ead/Ea22-like protein DUF1664 PF07889.12 KHN70025.1 - 4.7 7.3 8.8 9.4 6.3 5.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CorA PF01544.18 KHN70025.1 - 4.8 6.4 8.6 1.1 8.5 3.7 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein EamA PF00892.20 KHN70026.1 - 5.9e-07 29.7 11.5 5.9e-07 29.7 11.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Chs7 PF12271.8 KHN70027.1 - 0.013 14.8 1.0 0.013 14.8 1.0 1.6 1 1 1 2 2 2 0 Chitin synthase export chaperone Prefoldin_3 PF13758.6 KHN70027.1 - 0.044 13.8 0.2 0.074 13.1 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit MFS_2 PF13347.6 KHN70027.1 - 0.051 12.1 0.0 0.051 12.1 0.0 2.0 1 1 0 2 2 2 0 MFS/sugar transport protein CCB1 PF12046.8 KHN70027.1 - 0.057 12.8 0.1 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B YEATS PF03366.16 KHN70028.1 - 4.2e-19 68.3 0.5 6.3e-19 67.7 0.5 1.3 1 0 0 1 1 1 1 YEATS family Ank_2 PF12796.7 KHN70029.1 - 5.7e-11 42.9 0.2 2.8e-07 31.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KHN70029.1 - 3e-08 34.0 0.7 2.3e-07 31.2 0.3 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KHN70029.1 - 3.7e-05 24.0 0.8 0.24 11.9 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KHN70029.1 - 6.8e-05 23.1 0.5 0.00046 20.4 0.5 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KHN70029.1 - 0.00071 19.8 4.1 0.06 13.9 0.1 5.1 6 0 0 6 6 6 1 Ankyrin repeat EF-hand_7 PF13499.6 KHN70031.1 - 3.9e-08 33.6 0.9 0.00051 20.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KHN70031.1 - 1.6e-07 30.7 3.9 0.0015 18.3 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KHN70031.1 - 3.2e-06 26.3 4.7 0.0051 16.3 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KHN70031.1 - 0.044 13.6 1.0 1.2 9.1 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 KHN70031.1 - 0.98 9.0 6.7 3 7.5 0.6 2.6 2 0 0 2 2 2 0 EF hand Ras PF00071.22 KHN70032.1 - 7.9e-40 136.1 0.0 9e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN70032.1 - 5.6e-19 68.5 0.0 8.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KHN70032.1 - 3.2e-06 26.8 0.0 5.6e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KHN70032.1 - 3.4e-06 27.1 0.0 6.5e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KHN70032.1 - 0.0018 17.8 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 KHN70032.1 - 0.011 16.0 0.0 0.22 11.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KHN70032.1 - 0.027 14.0 0.0 0.093 12.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region FeoB_N PF02421.18 KHN70032.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B zf-RING_2 PF13639.6 KHN70033.1 - 1.3e-09 38.3 7.2 2.1e-09 37.6 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KHN70033.1 - 1.3e-06 28.1 4.8 3.1e-06 26.8 4.8 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KHN70033.1 - 3.4e-05 23.8 5.7 6.5e-05 22.9 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KHN70033.1 - 8.7e-05 22.3 6.4 0.00017 21.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KHN70033.1 - 0.00016 21.5 6.8 0.00016 21.5 6.8 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 KHN70033.1 - 0.00038 20.7 7.6 0.00099 19.3 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KHN70033.1 - 0.00072 19.4 7.8 0.00072 19.4 7.8 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KHN70033.1 - 0.0059 16.4 4.6 0.01 15.7 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KHN70033.1 - 0.029 14.2 3.6 0.07 13.0 3.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KHN70033.1 - 0.032 14.4 6.4 0.11 12.7 6.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 KHN70033.1 - 0.042 14.0 1.8 0.087 12.9 0.6 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 KHN70033.1 - 0.076 13.1 5.4 0.27 11.3 5.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KHN70033.1 - 0.08 12.6 4.8 0.15 11.7 4.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KHN70033.1 - 0.34 11.1 8.8 5.5 7.3 8.8 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain FYVE PF01363.21 KHN70033.1 - 1.7 8.8 6.7 14 5.9 6.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger DUF3488 PF11992.8 KHN70033.1 - 3.3 6.6 7.3 4.8 6.0 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) PHD PF00628.29 KHN70033.1 - 5.5 7.0 8.0 14 5.6 8.0 1.7 1 1 0 1 1 1 0 PHD-finger SNF2_N PF00176.23 KHN70034.1 - 3.3e-46 157.6 0.0 6.5e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KHN70034.1 - 3.9e-18 65.8 0.0 1.7e-17 63.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KHN70034.1 - 0.001 18.8 0.0 0.0029 17.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KHN70034.1 - 0.0035 17.1 0.1 0.0097 15.6 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase HEAT_2 PF13646.6 KHN70034.1 - 0.048 14.0 0.0 3 8.3 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats WD40 PF00400.32 KHN70035.1 - 8.1e-15 55.0 5.6 0.0004 21.1 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70035.1 - 2.5e-05 24.5 0.3 0.073 13.4 0.0 4.2 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KHN70035.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain CBFB_NFYA PF02045.15 KHN70036.1 - 9.1e-21 74.2 1.3 9.1e-21 74.2 1.3 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DnaJ PF00226.31 KHN70038.1 - 4.3e-09 36.4 0.4 6.6e-09 35.8 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Phage_30_3 PF08010.11 KHN70038.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Ribosomal_L18 PF17135.4 KHN70039.1 - 1.5e-35 122.3 0.6 1.9e-35 121.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KHN70039.1 - 0.00024 21.8 0.3 0.00038 21.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF211 PF02680.14 KHN70039.1 - 0.026 14.7 0.3 0.046 13.9 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Histone PF00125.24 KHN70042.1 - 1.7e-41 141.6 0.8 1.9e-41 141.5 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 KHN70042.1 - 1e-05 26.2 3.2 1.3e-05 25.8 3.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KHN70042.1 - 0.00011 22.3 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KHN70042.1 - 0.00016 22.0 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KHN70042.1 - 0.0075 16.5 0.7 0.011 16.0 0.0 1.8 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KHN70042.1 - 0.027 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated SPATA25 PF15218.6 KHN70042.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 PolyA_pol PF01743.20 KHN70044.1 - 1.1e-25 90.5 0.0 6.9e-25 87.9 0.0 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KHN70044.1 - 0.00012 21.7 0.1 0.00044 19.9 0.1 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Ras PF00071.22 KHN70045.1 - 1.2e-49 168.0 2.4 1.5e-49 167.7 2.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN70045.1 - 3.6e-36 124.0 0.8 6e-36 123.3 0.8 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN70045.1 - 4.1e-19 68.7 0.6 5.4e-19 68.3 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KHN70045.1 - 5.6e-09 35.7 1.3 6.7e-09 35.4 1.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KHN70045.1 - 2.1e-06 27.8 0.4 3.8e-06 27.0 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KHN70045.1 - 2.4e-06 27.1 0.1 3.1e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KHN70045.1 - 1.3e-05 24.8 2.1 7.9e-05 22.3 2.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KHN70045.1 - 0.00048 20.6 0.1 0.0031 17.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KHN70045.1 - 0.00072 19.8 0.1 0.0012 19.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 KHN70045.1 - 0.00083 19.1 1.0 0.0036 17.0 1.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 KHN70045.1 - 0.0021 18.1 0.5 0.0046 17.0 0.3 1.7 1 1 1 2 2 2 1 AAA domain Septin PF00735.18 KHN70045.1 - 0.0048 16.2 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_7 PF12775.7 KHN70045.1 - 0.011 15.3 0.2 0.047 13.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KHN70045.1 - 0.012 15.5 0.2 0.065 13.1 0.0 2.1 1 1 2 3 3 3 0 RsgA GTPase AAA_5 PF07728.14 KHN70045.1 - 0.015 15.3 0.0 0.049 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KHN70045.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KHN70045.1 - 0.026 14.1 0.1 0.055 13.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 KHN70045.1 - 0.059 13.3 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KHN70045.1 - 0.063 13.7 0.3 0.35 11.3 0.2 2.3 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KHN70045.1 - 0.14 12.6 0.3 0.27 11.7 0.3 1.7 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 KHN70045.1 - 0.26 10.4 4.0 1.1 8.4 0.3 2.7 1 1 1 2 2 2 0 G-protein alpha subunit MASE4 PF17158.4 KHN70046.1 - 0.027 13.7 0.3 0.027 13.7 0.3 1.7 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain RRF PF01765.19 KHN70046.1 - 0.14 12.1 3.6 0.29 11.1 3.6 1.5 1 0 0 1 1 1 0 Ribosome recycling factor 7TMR-DISM_7TM PF07695.11 KHN70046.1 - 1 9.2 12.5 0.28 11.0 0.7 2.2 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4131 PF13567.6 KHN70046.1 - 1.5 8.4 5.8 8.6 6.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF5391 PF17369.2 KHN70046.1 - 2 8.5 7.2 0.36 10.9 3.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5391) HIP1_clath_bdg PF16515.5 KHN70046.1 - 2.4 8.8 5.1 23 5.7 1.4 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YrhC PF14143.6 KHN70046.1 - 4.6 7.4 7.5 0.23 11.6 0.6 2.3 2 0 0 2 2 2 0 YrhC-like protein YabA PF06156.13 KHN70046.1 - 7.7 7.2 7.5 18 6.0 0.3 3.4 2 1 0 3 3 3 0 Initiation control protein YabA GrpE PF01025.19 KHN70046.1 - 9.2 5.9 9.3 1.1 8.9 0.3 2.6 2 1 0 2 2 2 0 GrpE AAA PF00004.29 KHN70047.1 - 9.7e-53 178.1 0.1 3e-38 131.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KHN70047.1 - 3.6e-11 43.5 2.1 0.00012 22.4 0.0 3.9 2 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KHN70047.1 - 1.8e-09 38.2 0.1 0.013 15.9 0.1 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KHN70047.1 - 3.5e-09 37.3 0.0 0.00017 22.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 KHN70047.1 - 4.6e-09 35.9 0.0 1.3e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 KHN70047.1 - 8.5e-09 35.8 0.0 0.00069 20.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 KHN70047.1 - 1.4e-08 34.9 0.0 0.0012 18.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KHN70047.1 - 9.7e-08 32.3 0.0 0.00013 22.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KHN70047.1 - 1.9e-07 31.1 1.9 0.0024 17.9 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KHN70047.1 - 1.5e-06 28.0 0.0 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KHN70047.1 - 7.6e-06 25.8 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KHN70047.1 - 9e-06 25.2 0.1 0.0032 16.9 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KHN70047.1 - 1.4e-05 24.8 1.6 1.2 8.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 KHN70047.1 - 2.2e-05 24.7 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KHN70047.1 - 4.3e-05 23.5 0.3 1.3 8.9 0.0 3.7 4 0 0 4 4 4 2 NACHT domain TsaE PF02367.17 KHN70047.1 - 6.4e-05 23.0 0.0 0.5 10.4 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KHN70047.1 - 7e-05 22.4 0.2 0.64 9.5 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region ABC_tran PF00005.27 KHN70047.1 - 9.6e-05 22.9 0.1 0.25 11.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter NB-ARC PF00931.22 KHN70047.1 - 0.00013 21.2 1.3 0.097 11.8 0.0 3.5 3 0 0 3 3 3 1 NB-ARC domain TIP49 PF06068.13 KHN70047.1 - 0.00021 20.6 0.0 0.49 9.5 0.1 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KHN70047.1 - 0.00023 20.9 0.0 0.42 10.4 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 KHN70047.1 - 0.00052 19.8 0.1 0.42 10.3 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain PhoH PF02562.16 KHN70047.1 - 0.0019 17.7 0.0 2.2 7.7 0.0 2.6 2 1 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 KHN70047.1 - 0.0028 17.0 5.0 0.083 12.2 0.1 3.3 4 0 0 4 4 3 1 KaiC AAA_3 PF07726.11 KHN70047.1 - 0.0052 16.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 KHN70047.1 - 0.0086 16.1 0.3 1.7 8.7 0.1 3.0 3 0 0 3 3 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KHN70047.1 - 0.0091 15.9 0.1 4.5 7.1 0.0 3.0 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 KHN70047.1 - 0.011 16.0 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KHN70047.1 - 0.012 15.1 0.6 9.9 5.5 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein ResIII PF04851.15 KHN70047.1 - 0.014 15.4 0.0 0.58 10.1 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KHN70047.1 - 0.032 14.1 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 KHN70047.1 - 0.038 13.6 0.1 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5432 PF17497.2 KHN70047.1 - 0.095 12.8 0.4 0.28 11.3 0.1 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5432) AAA_30 PF13604.6 KHN70047.1 - 0.11 12.3 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KHN70047.1 - 0.14 11.9 1.5 1.7 8.5 0.2 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.6 KHN70047.1 - 0.35 11.3 3.3 35 4.8 0.3 3.7 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KHN70047.1 - 2.4 8.6 5.7 20 5.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain TPR_19 PF14559.6 KHN70048.1 - 3.4e-08 33.9 0.2 8.7e-05 23.0 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KHN70048.1 - 1.2e-07 31.9 1.0 8.7e-05 22.7 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KHN70048.1 - 1e-06 28.3 3.5 0.18 12.0 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KHN70048.1 - 0.0012 19.1 0.0 0.63 10.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KHN70048.1 - 0.0062 17.1 1.8 4.1 8.2 0.1 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KHN70048.1 - 0.0092 16.1 5.0 0.74 10.2 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KHN70048.1 - 0.014 15.2 9.8 0.89 9.5 1.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KHN70048.1 - 0.028 14.1 0.0 0.26 11.0 0.0 2.7 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 KHN70048.1 - 0.037 14.8 0.0 27 5.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Homeodomain PF00046.29 KHN70049.1 - 1.2e-13 50.7 3.5 1.6e-13 50.3 3.5 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KHN70049.1 - 0.00016 21.5 1.4 0.00028 20.7 1.2 1.7 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 KHN70049.1 - 0.013 15.0 0.2 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Carb_kinase PF01256.17 KHN70050.1 - 3.2e-33 115.2 0.0 4.1e-31 108.3 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase eRF1_1 PF03463.15 KHN70051.1 - 1.8e-27 95.9 2.3 2.8e-27 95.3 2.3 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KHN70051.1 - 5e-12 46.3 0.1 1.7e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 eRF1 domain 3 Hist_deacetyl PF00850.19 KHN70052.1 - 8e-82 275.2 0.0 9.8e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain UPF0160 PF03690.13 KHN70053.1 - 3.4e-85 286.5 0.0 3.9e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) AAA PF00004.29 KHN70055.1 - 9.9e-42 142.5 0.0 2e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN70055.1 - 2.4e-10 40.1 0.3 5.3e-10 38.9 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KHN70055.1 - 2.1e-06 27.8 0.0 1e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KHN70055.1 - 6.8e-05 23.3 0.1 0.0014 19.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KHN70055.1 - 0.00046 20.7 0.0 0.0012 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 KHN70055.1 - 0.00049 19.3 0.0 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KHN70055.1 - 0.00065 20.0 0.1 0.021 15.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KHN70055.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KHN70055.1 - 0.0017 18.5 0.0 0.0052 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 KHN70055.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KHN70055.1 - 0.0075 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KHN70055.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 KHN70055.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KHN70055.1 - 0.016 15.6 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KHN70055.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KHN70055.1 - 0.02 14.7 0.0 0.078 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KHN70055.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 KHN70055.1 - 0.034 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_3 PF07726.11 KHN70055.1 - 0.047 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KHN70055.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KHN70055.1 - 0.081 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 KHN70055.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KHN70055.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ELP6 PF09807.9 KHN70056.1 - 0.0039 16.7 0.1 1.3 8.4 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ThiF PF00899.21 KHN70057.1 - 1.7e-60 204.4 0.2 2.6e-60 203.8 0.2 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KHN70057.1 - 7.4e-06 26.4 0.1 5.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 KHN70057.1 - 0.00098 19.4 0.5 0.012 15.9 0.5 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KHN70057.1 - 0.13 12.3 0.4 14 5.8 0.0 2.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Hs1pro-1_C PF07014.12 KHN70057.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus DUF2256 PF10013.9 KHN70057.1 - 1.3 9.2 4.4 0.86 9.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF1655 PF07868.11 KHN70058.1 - 0.15 12.2 0.3 0.91 9.6 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1655) Cytidylate_kin PF02224.18 KHN70059.1 - 5.8e-58 196.1 2.1 6.6e-58 195.9 2.1 1.0 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 KHN70059.1 - 1.9e-08 35.0 2.3 1.1e-07 32.5 2.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KHN70059.1 - 7.3e-08 32.9 1.9 1.8e-05 25.2 1.0 2.8 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 KHN70059.1 - 2.6e-07 31.0 1.7 5.8e-07 29.8 1.7 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family dNK PF01712.19 KHN70059.1 - 0.0002 21.3 0.9 0.00045 20.1 0.9 1.6 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 KHN70059.1 - 0.026 14.7 0.1 0.064 13.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain ADK PF00406.22 KHN70059.1 - 0.082 13.0 1.7 0.33 11.0 0.3 2.4 1 1 1 2 2 2 0 Adenylate kinase EMP24_GP25L PF01105.24 KHN70060.1 - 6.4e-09 36.0 0.5 1e-08 35.4 0.5 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Acetate_kinase PF00871.17 KHN70060.1 - 0.0044 15.8 0.3 0.0056 15.4 0.3 1.0 1 0 0 1 1 1 1 Acetokinase family CUB_2 PF02408.20 KHN70060.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 CUB-like domain GPI2 PF06432.11 KHN70061.1 - 5.9e-13 48.9 14.6 9.7e-13 48.2 14.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF2818 PF10993.8 KHN70061.1 - 0.14 12.7 0.4 0.14 12.7 0.4 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2818) ATP_bind_3 PF01171.20 KHN70062.1 - 8e-18 64.8 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 KHN70062.1 - 0.00037 19.4 0.2 0.00073 18.4 0.2 1.5 1 1 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KHN70062.1 - 0.0061 16.2 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) CTU2 PF10288.9 KHN70062.1 - 0.0064 16.7 2.9 0.029 14.6 0.2 2.8 2 1 1 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 PAPS_reduct PF01507.19 KHN70062.1 - 0.0074 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueH PF02677.14 KHN70062.1 - 0.026 14.6 0.1 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Epoxyqueuosine reductase QueH NAD_synthase PF02540.17 KHN70062.1 - 0.057 12.5 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD synthase PHF5 PF03660.14 KHN70062.1 - 2.9 8.1 8.2 8.3 6.7 0.1 3.0 4 0 0 4 4 4 0 PHF5-like protein DZR PF12773.7 KHN70062.1 - 6 7.0 8.8 0.9 9.6 0.1 3.1 3 1 0 3 3 3 0 Double zinc ribbon NUP214 PF16755.5 KHN70063.1 - 5.4e-07 29.2 0.1 9.2e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40_like PF17005.5 KHN70063.1 - 8.4e-05 22.0 6.4 0.001 18.5 2.2 2.6 1 1 1 2 2 2 2 WD40-like domain WD40 PF00400.32 KHN70063.1 - 0.086 13.7 0.0 7.6 7.6 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat PQQ_3 PF13570.6 KHN70063.1 - 0.15 12.6 0.0 41 4.8 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_L3 PF00297.22 KHN70064.1 - 4.3e-124 414.3 11.1 4.9e-124 414.0 11.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF2059 PF09832.9 KHN70064.1 - 0.043 13.9 0.1 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) UMPH-1 PF05822.12 KHN70065.1 - 0.04 13.4 0.5 0.049 13.1 0.5 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PMM PF03332.13 KHN70065.1 - 0.075 12.8 1.6 0.085 12.6 1.6 1.1 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase z-alpha PF02295.17 KHN70065.1 - 0.44 10.6 2.7 1.9 8.6 0.4 2.3 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain AhpC-TSA PF00578.21 KHN70066.1 - 1.1e-23 83.4 0.0 1.3e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KHN70066.1 - 4.1e-09 36.3 0.0 4.6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Peptidase_S8 PF00082.22 KHN70067.1 - 2.9e-16 59.6 0.1 5.5e-16 58.7 0.1 1.6 1 1 0 1 1 1 1 Subtilase family Homeodomain PF00046.29 KHN70069.1 - 5.4e-19 67.8 1.7 1.1e-18 66.8 1.7 1.5 1 0 0 1 1 1 1 Homeodomain Syja_N PF02383.18 KHN70070.1 - 6.3e-45 153.9 1.2 4.4e-44 151.1 1.2 2.0 1 1 0 1 1 1 1 SacI homology domain SicP-binding PF09119.10 KHN70070.1 - 0.096 12.7 0.0 0.44 10.6 0.0 2.1 2 0 0 2 2 2 0 SicP binding CH PF00307.31 KHN70071.1 - 5.6e-14 52.3 0.5 7.2e-14 51.9 0.5 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Rad51 PF08423.11 KHN70073.1 - 2e-08 33.9 0.2 6.5e-08 32.2 0.1 1.7 1 1 1 2 2 2 1 Rad51 Stn1 PF10451.9 KHN70073.1 - 0.0015 17.5 0.4 0.0021 17.1 0.4 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 AAA_25 PF13481.6 KHN70073.1 - 0.0028 17.3 0.2 0.13 11.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 KHN70073.1 - 0.0033 16.8 3.6 0.029 13.7 0.4 2.3 1 1 1 2 2 2 2 KaiC AAA PF00004.29 KHN70073.1 - 0.0058 17.1 0.1 0.019 15.4 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KHN70073.1 - 0.048 13.0 1.2 0.49 9.7 0.3 2.0 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KHN70073.1 - 0.06 13.6 2.3 0.27 11.5 2.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN70073.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_C PF00137.21 KHN70074.1 - 0.00024 21.4 21.7 0.00068 19.9 6.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C MatE PF01554.18 KHN70074.1 - 1.7 8.3 15.9 0.081 12.6 9.8 1.8 2 0 0 2 2 2 0 MatE STAT6_C PF14596.6 KHN70075.1 - 0.19 11.7 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 STAT6 C-terminal NMT PF01233.19 KHN70076.1 - 1.2e-29 103.2 0.0 2.2e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 KHN70076.1 - 9e-28 97.2 0.0 1.8e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 KHN70076.1 - 3.5e-06 27.2 0.1 7.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KHN70076.1 - 0.0043 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KHN70076.1 - 0.0088 16.1 0.0 0.029 14.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KHN70076.1 - 0.026 15.0 0.1 0.073 13.5 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KHN70076.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PQQ_3 PF13570.6 KHN70077.1 - 2.4e-07 31.1 2.1 0.9 10.1 0.0 3.7 3 0 0 3 3 3 3 PQQ-like domain PI3_PI4_kinase PF00454.27 KHN70078.1 - 7.4e-32 111.1 0.7 3.8e-30 105.5 0.7 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CnrY PF17524.2 KHN70079.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma factor CnrY XPG_I PF00867.18 KHN70080.1 - 1.2e-29 102.5 0.3 2.6e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KHN70080.1 - 1.4e-27 96.1 0.0 2.6e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KHN70080.1 - 1.2e-06 29.0 0.0 3.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KHN70080.1 - 0.006 17.2 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain XRN_N PF03159.18 KHN70080.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus HHH_2 PF12826.7 KHN70080.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TFIIA PF03153.13 KHN70081.1 - 2.1e-16 61.0 8.5 2.4e-15 57.4 1.8 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Far-17a_AIG1 PF04750.14 KHN70082.1 - 1.7e-22 79.8 10.2 1.9e-22 79.6 10.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3262 PF11660.8 KHN70082.1 - 0.12 12.8 2.5 0.46 10.9 2.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Far-17a_AIG1 PF04750.14 KHN70083.1 - 3.2e-25 88.6 14.2 4e-25 88.3 14.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF1418 PF07214.12 KHN70083.1 - 0.14 12.0 1.1 0.54 10.2 0.1 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) Orf78 PF06024.12 KHN70083.1 - 0.96 9.8 0.1 0.96 9.8 0.1 2.8 3 0 0 3 3 3 0 Orf78 (ac78) Myb_DNA-bind_7 PF15963.5 KHN70084.1 - 2.9e-23 81.5 0.8 4.1e-23 81.1 0.2 1.6 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KHN70084.1 - 1.1e-05 25.6 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain B PF02216.16 KHN70084.1 - 0.0062 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 B domain Myb_DNA-bind_6 PF13921.6 KHN70084.1 - 0.0093 16.2 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA_22 PF13401.6 KHN70085.1 - 2.1e-10 41.0 0.0 3.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KHN70085.1 - 8.3e-08 32.7 0.1 3.3e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KHN70085.1 - 4.1e-07 30.6 0.0 4.4e-05 23.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KHN70085.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 KHN70085.1 - 0.0002 21.4 0.0 0.00045 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KHN70085.1 - 0.00022 21.0 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KHN70085.1 - 0.00024 21.5 1.9 0.023 15.0 1.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KHN70085.1 - 0.00068 19.7 0.0 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) zf-ACC PF17848.1 KHN70085.1 - 0.0016 18.4 1.6 0.0044 17.0 1.6 1.8 1 0 0 1 1 1 1 Acetyl-coA carboxylase zinc finger domain AAA_lid_10 PF17872.1 KHN70085.1 - 0.0017 18.4 1.5 0.0024 17.9 0.3 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_18 PF13238.6 KHN70085.1 - 0.0017 18.9 0.0 0.0039 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 KHN70085.1 - 0.0037 16.9 0.0 0.0051 16.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 KHN70085.1 - 0.0056 16.6 0.1 0.026 14.4 0.1 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KHN70085.1 - 0.0095 15.1 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 KHN70085.1 - 0.03 13.6 0.2 0.061 12.6 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Microtub_bd PF16796.5 KHN70085.1 - 0.035 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding cobW PF02492.19 KHN70085.1 - 0.041 13.5 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_2 PF07724.14 KHN70085.1 - 0.043 13.9 0.8 0.11 12.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KHN70085.1 - 0.052 13.3 0.3 0.9 9.3 0.1 2.3 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 KHN70085.1 - 0.061 12.3 0.0 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KHN70085.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 KHN70085.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.4 2 0 0 2 2 2 0 Kinesin motor domain AAA_33 PF13671.6 KHN70085.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KHN70085.1 - 0.26 10.4 3.6 0.69 9.0 2.0 2.2 2 1 0 2 2 2 0 PIF1-like helicase 14-3-3 PF00244.20 KHN70087.1 - 1.3e-83 279.9 4.9 1.4e-83 279.7 4.9 1.0 1 0 0 1 1 1 1 14-3-3 protein MS_channel PF00924.18 KHN70088.1 - 5.5e-11 42.4 3.5 1.2e-10 41.3 3.5 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3810 PF12725.7 KHN70088.1 - 0.13 11.6 3.2 0.16 11.3 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) CAP PF00188.26 KHN70089.1 - 3.7e-12 47.2 0.1 1.6e-11 45.1 0.0 2.2 2 0 0 2 2 2 1 Cysteine-rich secretory protein family FeoC PF09012.10 KHN70089.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator Pkinase PF00069.25 KHN70090.1 - 8.1e-69 231.9 0.0 1.2e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70090.1 - 1.1e-31 110.1 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN70090.1 - 4.8e-09 35.9 0.0 7.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KHN70090.1 - 2.3e-05 23.5 0.6 6.3e-05 22.1 0.6 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KHN70090.1 - 5.8e-05 23.1 0.7 0.006 16.5 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KHN70090.1 - 0.00029 20.3 0.0 0.00061 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KHN70090.1 - 0.00047 19.8 0.2 0.00047 19.8 0.2 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KHN70090.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L30 PF00327.20 KHN70093.1 - 1.2e-12 47.5 1.1 2.7e-12 46.4 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF4829 PF16111.5 KHN70093.1 - 0.13 13.0 3.5 0.46 11.3 2.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4829) zf-C2H2_aberr PF17017.5 KHN70094.1 - 2.9e-06 27.5 10.0 0.0047 17.1 1.2 2.4 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 KHN70094.1 - 8.7e-06 25.9 9.5 0.0093 16.4 0.3 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KHN70094.1 - 0.00014 22.4 7.7 0.12 13.2 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KHN70094.1 - 0.0033 17.8 0.6 0.0033 17.8 0.6 4.3 4 1 0 4 4 4 1 Zinc-finger double domain zf_Hakai PF18408.1 KHN70094.1 - 0.03 14.0 3.2 2.1 8.1 0.0 2.6 3 0 0 3 3 3 0 C2H2 Hakai zinc finger domain zf-BED PF02892.15 KHN70094.1 - 0.089 12.8 5.0 3.2 7.8 0.8 2.6 2 0 0 2 2 2 0 BED zinc finger ThiF PF00899.21 KHN70095.1 - 1.1e-84 283.7 0.3 1.4e-55 188.3 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KHN70095.1 - 7.2e-60 203.0 3.3 5.5e-42 144.4 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KHN70095.1 - 2.6e-06 28.0 0.1 8.3e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KHN70095.1 - 7.4e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 KHN70095.1 - 0.00019 21.5 0.3 0.00071 19.7 0.3 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain NAD_binding_7 PF13241.6 KHN70095.1 - 0.024 15.0 1.4 0.49 10.9 0.0 3.3 3 1 0 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KHN70095.1 - 0.078 13.0 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase tRNA_int_endo PF01974.17 KHN70096.1 - 2.3e-14 53.2 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pkinase PF00069.25 KHN70097.1 - 4.9e-29 101.5 0.5 5.9e-29 101.2 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70097.1 - 2.3e-15 56.6 0.1 2.9e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KHN70097.1 - 1.6e-07 30.5 0.0 2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KHN70097.1 - 0.0029 17.6 0.0 0.025 14.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KHN70097.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KHN70097.1 - 0.013 14.8 0.1 0.022 14.1 0.1 1.4 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KHN70097.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sec1 PF00995.23 KHN70098.1 - 3.1e-74 251.2 3.5 3.9e-74 250.9 3.5 1.1 1 0 0 1 1 1 1 Sec1 family TSP_NTD PF17804.1 KHN70098.1 - 0.053 13.8 0.4 0.11 12.7 0.4 1.5 1 0 0 1 1 1 0 Tail specific protease N-terminal domain Haspin_kinase PF12330.8 KHN70099.1 - 1.6e-49 168.8 17.9 4e-48 164.2 17.9 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 KHN70099.1 - 2.1e-05 23.9 0.1 0.00015 21.2 0.1 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 KHN70099.1 - 0.00015 21.4 0.5 0.00015 21.4 0.5 2.4 2 2 1 3 3 3 1 Choline/ethanolamine kinase Kdo PF06293.14 KHN70099.1 - 0.021 14.2 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KHN70099.1 - 0.083 12.8 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3562 PF12085.8 KHN70100.1 - 0.011 15.3 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) DUF5089 PF17002.5 KHN70101.1 - 0.0039 17.1 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5089) UPF0203 PF05254.12 KHN70103.1 - 0.48 10.7 3.2 14 6.0 0.0 3.6 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0203) LSM PF01423.22 KHN70104.1 - 1.3e-12 47.2 0.1 1.5e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KHN70104.1 - 0.00019 21.5 0.0 0.00024 21.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KHN70104.1 - 0.00045 20.2 0.0 0.00058 19.9 0.0 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain DUF5092 PF17010.5 KHN70105.1 - 5e-38 130.6 3.6 1.1e-31 109.9 0.9 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF5092) Tubulin PF00091.25 KHN70106.1 - 1.4e-69 234.2 0.0 2.6e-69 233.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KHN70106.1 - 2.4e-42 144.1 0.1 3.8e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KHN70106.1 - 1.5e-05 25.2 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KHN70106.1 - 0.089 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KHN70106.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Sedlin_N PF04628.13 KHN70107.1 - 1.5e-09 38.1 0.8 1.7e-09 37.9 0.8 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Urm1 PF09138.11 KHN70108.1 - 1.2e-11 44.8 0.1 1.3e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KHN70108.1 - 0.048 14.3 0.0 0.072 13.7 0.0 1.4 1 1 0 1 1 1 0 ThiS family zf-C2H2 PF00096.26 KHN70109.1 - 1.6e-14 53.5 59.6 0.00017 21.9 1.2 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KHN70109.1 - 1.6e-11 44.0 58.0 0.0043 17.8 1.8 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KHN70109.1 - 1.3e-07 31.7 59.2 0.00028 21.2 1.8 6.6 5 1 1 6 6 6 4 Zinc-finger double domain zf-C2H2_3rep PF18868.1 KHN70109.1 - 0.00024 21.8 7.3 0.00024 21.8 7.3 2.7 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KHN70109.1 - 0.00066 19.9 39.6 0.71 10.2 8.1 5.7 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding Zn-C2H2_12 PF18112.1 KHN70109.1 - 0.012 16.0 16.6 0.079 13.4 2.3 5.1 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_5 PF13909.6 KHN70109.1 - 0.031 14.0 2.3 0.031 14.0 2.3 5.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain PP_kinase PF02503.17 KHN70110.1 - 0.038 13.6 0.2 0.39 10.3 0.0 2.4 2 0 0 2 2 2 0 Polyphosphate kinase middle domain RRM_1 PF00076.22 KHN70112.1 - 6.3e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KHN70113.1 - 3.7e-07 29.9 0.2 3.2e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 KHN70114.1 - 8.6e-30 102.4 1.9 8.3e-14 51.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KHN70114.1 - 0.0026 17.8 0.1 0.63 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KHN70114.1 - 0.0041 17.1 0.3 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.6 KHN70114.1 - 0.0063 16.0 0.0 0.55 9.7 0.0 2.3 1 1 0 2 2 2 1 Domain of unknown function (DUF4283) Flexi_CP_N PF08358.10 KHN70114.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Carlavirus coat DUF4078 PF13300.6 KHN70114.1 - 1.6 9.1 5.4 2.1 8.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4078) Ribosomal_L34e PF01199.18 KHN70115.1 - 2.4e-28 98.3 7.4 2.8e-28 98.0 7.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e zf-C2H2_6 PF13912.6 KHN70115.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Mut7-C PF01927.16 KHN70115.1 - 0.019 15.1 1.6 0.025 14.7 1.6 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain Zn_ribbon_SprT PF17283.2 KHN70115.1 - 2.2 8.3 9.2 25 4.9 5.4 2.5 2 1 0 2 2 2 0 SprT-like zinc ribbon domain RNB PF00773.19 KHN70116.1 - 9.2e-88 294.7 0.0 1.3e-87 294.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KHN70116.1 - 5.6e-19 68.0 0.0 1.1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 KHN70116.1 - 0.00011 22.0 0.2 0.00022 21.0 0.2 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 KHN70116.1 - 0.0002 21.4 0.0 0.012 15.8 0.0 2.7 2 0 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 KHN70116.1 - 0.0022 17.7 1.4 0.0039 16.8 0.3 2.0 2 0 0 2 2 2 1 Ribonuclease B OB domain Rrp44_S1 PF17215.3 KHN70116.1 - 0.024 14.6 0.4 0.16 11.9 0.4 2.2 1 1 0 1 1 1 0 S1 domain FBPase PF00316.20 KHN70116.1 - 0.21 11.0 1.0 21 4.5 0.0 2.7 2 1 1 3 3 3 0 Fructose-1-6-bisphosphatase, N-terminal domain zf-C2H2_3rep PF18868.1 KHN70117.1 - 0.013 16.2 0.9 0.041 14.6 0.2 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PFK PF00365.20 KHN70118.1 - 7.8e-180 596.3 4.8 4.3e-109 364.2 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Lactamase_B_4 PF13691.6 KHN70118.1 - 0.0068 16.1 0.1 0.049 13.3 0.0 2.4 2 0 0 2 2 2 1 tRNase Z endonuclease Mpp10 PF04006.12 KHN70118.1 - 0.064 11.7 6.8 0.096 11.1 6.8 1.1 1 0 0 1 1 1 0 Mpp10 protein DAGK_cat PF00781.24 KHN70118.1 - 0.081 12.5 0.1 4.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Herpes_US9 PF06072.11 KHN70118.1 - 0.2 11.5 0.9 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 RNase_HII PF01351.18 KHN70119.1 - 1e-40 139.7 0.0 1.2e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII DUF3785 PF12653.7 KHN70119.1 - 0.0095 16.1 1.2 0.015 15.4 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3785) LRR_5 PF13306.6 KHN70119.1 - 0.019 14.9 0.4 0.032 14.2 0.4 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Aldolase_II PF00596.21 KHN70119.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain COX5A PF02284.16 KHN70119.1 - 0.14 12.1 0.1 0.5 10.4 0.0 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Va UCH PF00443.29 KHN70120.1 - 4.6e-27 95.1 0.1 7e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KHN70120.1 - 6.8e-17 61.6 3.9 6.8e-17 61.6 3.9 3.5 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KHN70120.1 - 0.00051 19.7 3.9 0.01 15.5 3.9 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S11 PF00411.19 KHN70121.1 - 5.8e-36 123.2 1.7 7.4e-36 122.9 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Rpr2 PF04032.16 KHN70122.1 - 0.02 15.1 1.0 0.041 14.2 1.0 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase PF00069.25 KHN70123.1 - 2.4e-38 132.0 0.1 4.5e-38 131.1 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70123.1 - 4.4e-13 49.1 0.0 7.8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Med5 PF08689.10 KHN70123.1 - 0.083 10.7 0.7 1.5 6.6 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit Med5 Homeodomain PF00046.29 KHN70124.1 - 1.6e-12 47.0 0.5 3e-12 46.2 0.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KHN70124.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Yip1 PF04893.17 KHN70125.1 - 3e-08 33.6 8.3 4e-08 33.2 8.3 1.2 1 0 0 1 1 1 1 Yip1 domain UCH PF00443.29 KHN70126.1 - 1.1e-37 130.0 0.0 2.3e-37 128.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KHN70126.1 - 1.3e-15 57.8 0.1 1.1e-11 44.9 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RSS_P20 PF11757.8 KHN70126.1 - 3.6 8.1 8.3 0.22 12.0 0.2 2.9 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Vac_ImportDeg PF09783.9 KHN70127.1 - 1.3e-37 129.1 0.2 1.6e-37 128.8 0.2 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein RabGAP-TBC PF00566.18 KHN70128.1 - 4.5e-33 114.7 3.1 2.1e-32 112.6 3.1 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RhoGEF PF00621.20 KHN70129.1 - 5.5e-22 78.9 0.9 1.2e-21 77.7 0.9 1.6 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KHN70129.1 - 1e-15 58.1 0.1 2.4e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 CNH domain PTEN_C2 PF10409.9 KHN70129.1 - 0.085 12.6 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein MutS_V PF00488.21 KHN70130.1 - 3.2e-58 196.9 0.3 5.6e-58 196.1 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KHN70130.1 - 3.4e-22 79.6 0.2 6.2e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.6 KHN70130.1 - 0.16 11.8 0.2 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Synaptobrevin PF00957.21 KHN70131.1 - 8.7e-09 35.1 0.2 1.9e-08 34.0 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF4878 PF12870.7 KHN70131.1 - 0.013 15.8 0.1 0.031 14.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4878) Longin PF13774.6 KHN70131.1 - 0.024 14.6 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain HSP70 PF00012.20 KHN70132.1 - 9.2e-169 562.4 7.9 8.6e-96 321.5 0.2 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KHN70132.1 - 3.3e-11 42.6 0.0 0.00012 21.1 0.0 3.6 3 0 0 3 3 3 3 MreB/Mbl protein FGGY_C PF02782.16 KHN70132.1 - 2.3e-05 24.2 0.0 4.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1539 PF07560.11 KHN70132.1 - 0.012 15.7 0.4 0.027 14.5 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) TACC_C PF05010.14 KHN70132.1 - 0.15 11.8 6.9 0.21 11.3 5.8 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Big_1 PF02369.16 KHN70132.1 - 0.28 11.2 5.2 0.14 12.1 0.7 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) MazG PF03819.17 KHN70133.1 - 0.062 13.5 0.1 0.26 11.5 0.1 2.1 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain V-ATPase_C PF03223.15 KHN70134.1 - 3.2e-35 122.2 2.3 4.2e-35 121.8 2.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Ribosomal_S30AE PF02482.19 KHN70134.1 - 0.11 13.3 2.5 22 5.9 0.1 3.1 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF2179 PF10035.9 KHN70134.1 - 0.15 11.8 0.0 0.5 10.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) TFIIS_C PF01096.18 KHN70135.1 - 5.8e-18 64.5 4.8 5.8e-18 64.5 4.8 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 KHN70135.1 - 0.0033 17.1 4.6 0.0059 16.3 1.9 2.3 1 1 1 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain SF3A2 PF16835.5 KHN70136.1 - 8.3e-14 51.7 0.1 1.6e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KHN70136.1 - 4.9e-05 23.6 1.5 0.0001 22.6 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KHN70136.1 - 0.018 15.3 0.7 0.041 14.2 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Arf PF00025.21 KHN70137.1 - 2.7e-34 118.1 0.0 3.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KHN70137.1 - 4.8e-14 52.3 0.0 7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN70137.1 - 7.9e-11 42.2 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KHN70137.1 - 9.5e-07 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KHN70137.1 - 2.1e-06 27.3 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KHN70137.1 - 7.6e-06 25.3 1.0 0.022 14.0 0.4 2.9 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KHN70137.1 - 1.8e-05 24.2 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KHN70137.1 - 8.2e-05 22.2 0.0 0.00058 19.5 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NOG1 PF06858.14 KHN70137.1 - 0.047 13.5 1.1 0.44 10.4 0.7 2.6 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 KHN70137.1 - 0.16 11.5 0.0 2.6 7.6 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B SIR2 PF02146.17 KHN70138.1 - 1.5e-31 109.7 0.1 2e-31 109.3 0.1 1.2 1 0 0 1 1 1 1 Sir2 family DUF1764 PF08576.10 KHN70139.1 - 1.6e-15 57.8 5.7 1.9e-15 57.6 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) RNA_pol_Rpb2_6 PF00562.28 KHN70140.1 - 4.2e-102 342.1 0.8 2.7e-71 240.7 0.1 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 KHN70140.1 - 5.5e-25 87.3 0.0 1.2e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 KHN70140.1 - 5.6e-23 81.1 0.2 1.6e-22 79.7 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.15 KHN70140.1 - 8.8e-23 80.9 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KHN70140.1 - 8.1e-17 61.5 0.2 1.5e-16 60.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KHN70140.1 - 7.2e-05 23.0 1.5 0.00024 21.3 0.8 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 Chitin_bind_4 PF00379.23 KHN70140.1 - 0.021 15.3 1.0 0.056 14.0 1.0 1.8 1 0 0 1 1 1 0 Insect cuticle protein OMP_b-brl_2 PF13568.6 KHN70140.1 - 0.052 13.6 0.6 0.2 11.7 0.4 1.9 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain WD40 PF00400.32 KHN70141.1 - 3.2e-30 103.7 17.5 2.5e-05 24.9 0.3 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat WD40_like PF17005.5 KHN70141.1 - 3.2e-12 46.4 4.3 2.3e-07 30.4 1.2 2.6 2 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 KHN70141.1 - 2.2e-08 34.3 1.2 0.64 10.3 0.1 4.7 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KHN70141.1 - 5.2e-05 23.2 1.7 0.012 15.7 0.0 4.0 1 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region NUP214 PF16755.5 KHN70141.1 - 0.0018 17.6 0.2 0.057 12.7 0.3 2.1 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Nup160 PF11715.8 KHN70141.1 - 0.024 13.3 0.3 0.1 11.3 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 NLE PF08154.12 KHN70141.1 - 0.042 14.4 0.2 0.11 13.1 0.2 1.7 1 1 0 1 1 1 0 NLE (NUC135) domain SPT16 PF08644.11 KHN70142.1 - 6.5e-24 84.8 0.0 1.5e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 KHN70142.1 - 1.2e-09 38.5 2.8 1.6e-09 38.1 0.5 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like FACT-Spt16_Nlob PF14826.6 KHN70142.1 - 2.9e-09 36.9 0.0 9.1e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KHN70142.1 - 4.8e-08 32.9 0.0 9.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 TraH_2 PF06871.11 KHN70142.1 - 0.13 11.9 2.8 0.26 10.9 2.8 1.4 1 0 0 1 1 1 0 TraH_2 CDC45 PF02724.14 KHN70142.1 - 1.2 7.3 10.4 2.3 6.4 10.4 1.4 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 KHN70142.1 - 1.3 8.9 12.5 0.88 9.4 3.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cyclin_N PF00134.23 KHN70143.1 - 0.0044 16.8 5.0 0.21 11.3 0.9 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain ABC2_membrane PF01061.24 KHN70145.1 - 9.4e-44 149.3 25.8 9.4e-44 149.3 25.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KHN70145.1 - 8.4e-26 91.1 0.0 1.4e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KHN70145.1 - 7.9e-06 25.2 14.8 7.9e-06 25.2 14.8 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 KHN70145.1 - 0.00027 20.9 0.3 0.1 12.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KHN70145.1 - 0.00032 20.2 0.1 0.0012 18.3 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KHN70145.1 - 0.00069 19.6 0.2 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 KHN70145.1 - 0.0077 16.0 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KHN70145.1 - 0.016 15.7 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KHN70145.1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KHN70145.1 - 0.024 15.0 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 KHN70145.1 - 0.038 13.7 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DnaB PF00772.21 KHN70145.1 - 0.04 14.0 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain AAA_16 PF13191.6 KHN70145.1 - 0.043 14.2 0.0 0.077 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 KHN70145.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KHN70145.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.23 KHN70145.1 - 0.07 13.2 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KHN70145.1 - 0.09 12.5 0.1 0.41 10.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KHN70145.1 - 0.092 13.2 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KHN70145.1 - 0.094 13.2 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KHN70145.1 - 0.099 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KHN70145.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KHN70145.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 KHN70145.1 - 0.45 9.7 10.9 0.9 8.8 10.9 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SPC12 PF06645.13 KHN70147.1 - 8e-23 80.3 0.9 9.1e-23 80.1 0.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) PUCC PF03209.15 KHN70147.1 - 0.003 16.6 0.2 0.0031 16.6 0.2 1.0 1 0 0 1 1 1 1 PUCC protein DUF2207 PF09972.9 KHN70147.1 - 0.17 10.6 0.5 0.18 10.5 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 KHN70147.1 - 0.48 9.7 2.9 0.54 9.6 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) LSM PF01423.22 KHN70149.1 - 5.7e-13 48.4 0.6 6.4e-13 48.2 0.6 1.1 1 0 0 1 1 1 1 LSM domain DUF4451 PF14616.6 KHN70150.1 - 9.1e-16 58.2 6.2 2.9e-15 56.6 6.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zf-DBF PF07535.12 KHN70150.1 - 0.24 11.5 2.0 0.27 11.4 0.3 2.1 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_jaz PF12171.8 KHN70150.1 - 1.9 8.9 10.0 5.5 7.4 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CW PF07496.15 KHN70150.1 - 4.9 7.3 7.2 5.8 7.0 0.6 2.3 2 0 0 2 2 2 0 CW-type Zinc Finger PIP5K PF01504.18 KHN70151.1 - 7.1e-56 189.4 0.4 6.4e-54 183.0 0.4 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ribosomal_L13e PF01294.18 KHN70152.1 - 3.4e-41 141.1 1.0 3.7e-41 140.9 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e Hom_end PF05204.14 KHN70152.1 - 0.11 12.6 0.1 0.47 10.6 0.0 1.8 2 0 0 2 2 2 0 Homing endonuclease Ribosomal_S9 PF00380.19 KHN70153.1 - 5.9e-22 78.5 0.0 6.7e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ATP-synt_F PF01990.17 KHN70154.1 - 4.6e-21 74.9 0.1 5.1e-21 74.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit ATPase PF06745.13 KHN70154.1 - 0.056 12.8 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 KaiC Skp1 PF01466.19 KHN70155.1 - 3.2e-10 40.0 0.9 7.1e-10 38.8 0.1 2.1 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KHN70155.1 - 0.032 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain RNA_pol_Rpb1_1 PF04997.12 KHN70156.1 - 1.3e-106 356.4 0.0 3.3e-106 355.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KHN70156.1 - 2.6e-89 299.2 0.1 4.1e-89 298.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KHN70156.1 - 1.8e-73 246.2 0.2 3.7e-73 245.2 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KHN70156.1 - 1.1e-48 165.2 0.3 8e-48 162.3 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KHN70156.1 - 6.6e-37 125.8 1.0 1.6e-36 124.5 1.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 KHN70156.1 - 1.9e-26 92.7 1.3 4.5e-26 91.4 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.13 KHN70156.1 - 1.8e-19 68.9 122.5 0.0038 17.5 11.9 8.0 2 1 7 11 11 11 10 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_6 PF04992.14 KHN70156.1 - 9e-18 64.8 4.0 4.9e-15 55.9 4.0 3.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 6 Herpes_BLLF1 PF05109.13 KHN70156.1 - 0.13 10.2 33.9 0.21 9.6 33.9 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) UDPGP PF01704.18 KHN70157.1 - 5.9e-177 588.4 0.2 7e-177 588.2 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Adaptin_N PF01602.20 KHN70158.1 - 1.1e-33 116.6 10.0 4e-24 85.1 2.0 2.7 2 1 1 3 3 3 2 Adaptin N terminal region COP-gamma_platf PF08752.10 KHN70158.1 - 7.6e-06 26.1 0.9 1.9e-05 24.9 0.9 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 KHN70158.1 - 3.2e-05 24.2 0.2 2.6 8.5 0.0 4.6 4 2 1 5 5 5 1 HEAT repeats Cnd1 PF12717.7 KHN70158.1 - 8.5e-05 22.7 8.1 0.22 11.5 0.1 4.3 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KHN70158.1 - 0.046 14.0 2.3 1.1 9.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Xpo1 PF08389.12 KHN70158.1 - 0.062 13.4 0.4 19 5.3 0.0 3.2 3 1 0 3 3 3 0 Exportin 1-like protein Cnd3 PF12719.7 KHN70158.1 - 0.066 12.4 0.5 0.58 9.3 0.2 2.4 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KHN70158.1 - 0.2 12.2 0.1 29 5.3 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat SKIP_SNW PF02731.15 KHN70159.1 - 1.2e-06 28.3 0.5 1.5e-06 27.9 0.5 1.3 1 1 0 1 1 1 1 SKIP/SNW domain Chs7 PF12271.8 KHN70160.1 - 3.4e-22 79.1 23.2 7e-22 78.1 23.2 1.4 1 1 0 1 1 1 1 Chitin synthase export chaperone ABC_tran PF00005.27 KHN70161.1 - 2.4e-29 102.6 0.0 5.2e-29 101.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.23 KHN70161.1 - 4.2e-19 69.3 5.7 6.2e-19 68.7 5.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KHN70161.1 - 4.1e-07 29.7 1.9 3.8e-05 23.2 1.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 KHN70161.1 - 0.00037 20.5 0.1 0.0062 16.5 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_29 PF13555.6 KHN70161.1 - 0.00045 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KHN70161.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KHN70161.1 - 0.0015 18.8 0.0 0.011 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KHN70161.1 - 0.0027 18.2 0.1 0.0067 17.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KHN70161.1 - 0.0048 16.8 0.2 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 KHN70161.1 - 0.0058 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KHN70161.1 - 0.0063 16.9 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KHN70161.1 - 0.0068 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 KHN70161.1 - 0.0085 16.4 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KHN70161.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 KHN70161.1 - 0.014 15.2 0.2 0.21 11.3 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 KHN70161.1 - 0.017 14.8 1.3 0.04 13.6 0.0 2.2 2 2 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KHN70161.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 KHN70161.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 KHN70161.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KHN70161.1 - 0.11 12.9 0.1 0.76 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MeaB PF03308.16 KHN70161.1 - 0.11 11.4 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KHN70161.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KHN70161.1 - 0.16 11.7 0.4 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 KHN70161.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Ribosomal_L31e PF01198.19 KHN70162.1 - 7.5e-13 48.5 0.5 9e-13 48.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Glyco_hydro_5_C PF18564.1 KHN70162.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.3 1 1 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain Cpn60_TCP1 PF00118.24 KHN70163.1 - 1.8e-147 491.9 10.1 2e-147 491.8 10.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Amj PF10997.8 KHN70163.1 - 0.14 11.4 0.9 0.42 9.9 0.2 2.0 2 0 0 2 2 2 0 Alternate to MurJ PSP1 PF04468.12 KHN70164.1 - 8.5e-29 99.7 1.1 8.5e-29 99.7 1.1 1.9 2 1 0 2 2 2 1 PSP1 C-terminal conserved region DUF3885 PF13021.6 KHN70164.1 - 0.11 12.6 0.1 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) TatD_DNase PF01026.21 KHN70165.1 - 8e-50 169.6 0.0 9.6e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CENP-C_C PF11699.8 KHN70166.1 - 2.2e-05 24.5 0.6 3.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.11 KHN70166.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain LRR_4 PF12799.7 KHN70167.1 - 9.1e-14 51.4 21.4 0.09 13.2 0.1 9.2 2 1 5 9 9 9 7 Leucine Rich repeats (2 copies) Nbl1_Borealin_N PF10444.9 KHN70167.1 - 0.048 13.3 0.5 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Ribosomal_L28 PF00830.19 KHN70167.1 - 0.056 13.6 6.0 9.7 6.5 3.7 3.2 3 0 0 3 3 3 0 Ribosomal L28 family Apis_Csd PF11671.8 KHN70168.1 - 2.6 8.0 6.2 42 4.1 0.0 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein Mcl1_mid PF12341.8 KHN70169.1 - 6.7e-07 29.0 0.6 5.1e-06 26.1 0.2 2.6 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region PQQ_3 PF13570.6 KHN70169.1 - 0.18 12.3 0.0 7.9 7.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Aminotran_1_2 PF00155.21 KHN70171.1 - 1e-23 84.1 0.1 1.4e-23 83.7 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KHN70171.1 - 0.00024 19.7 0.1 0.00034 19.3 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Thioredoxin PF00085.20 KHN70172.1 - 8.3e-18 64.3 0.1 3.5e-13 49.4 0.2 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 KHN70172.1 - 1.4e-06 28.4 2.6 0.023 14.6 1.3 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 KHN70172.1 - 0.00051 20.0 0.0 0.094 12.7 0.0 3.0 2 1 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 KHN70172.1 - 0.0099 16.2 0.2 1.6 9.1 0.0 3.7 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KHN70172.1 - 0.059 13.8 0.1 4.2 7.9 0.2 2.8 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KHN70172.1 - 0.068 13.2 0.8 41 4.3 0.0 3.3 2 1 1 3 3 3 0 Thioredoxin domain DUF3153 PF11353.8 KHN70173.1 - 0.15 11.6 0.2 3.3 7.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3153) DAHP_synth_1 PF00793.20 KHN70174.1 - 0.037 12.9 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 DAHP synthetase I family HSBP1 PF06825.12 KHN70174.1 - 0.058 13.3 3.3 0.074 12.9 1.5 2.2 2 1 0 2 2 2 0 Heat shock factor binding protein 1 CDC45 PF02724.14 KHN70175.1 - 0.00062 18.2 0.7 0.0029 16.0 0.2 2.1 2 1 0 2 2 2 1 CDC45-like protein Ribosomal_L24e PF01246.20 KHN70176.1 - 9.6e-29 99.4 6.6 1.9e-28 98.5 6.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.14 KHN70176.1 - 0.00025 20.9 5.0 0.00025 20.9 5.0 1.9 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif SUIM_assoc PF16619.5 KHN70176.1 - 0.2 11.8 0.8 0.32 11.1 0.8 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L6 PF00347.23 KHN70177.1 - 2.6e-07 31.2 0.0 9.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 TFIIF_beta PF02270.15 KHN70178.1 - 2.1e-15 56.6 0.0 4.2e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KHN70178.1 - 2.7e-09 37.8 0.0 1.2e-08 35.7 0.0 1.9 1 1 1 2 2 2 1 TFIIF, beta subunit N-terminus Ribosomal_S17e PF00833.18 KHN70179.1 - 1.2e-35 122.1 1.3 1.4e-35 121.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribonuclease_P PF00825.18 KHN70179.1 - 0.021 14.9 0.9 0.044 13.9 0.4 1.7 1 1 1 2 2 2 0 Ribonuclease P Peptidase_S24 PF00717.23 KHN70180.1 - 6.9e-10 38.8 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Cu_bind_like PF02298.17 KHN70180.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain Ribosomal_L7Ae PF01248.26 KHN70181.1 - 5.4e-17 61.3 0.1 1e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GP63 PF17471.2 KHN70181.1 - 0.033 14.4 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Gene product 63 ubiquitin PF00240.23 KHN70182.1 - 7.3e-34 115.4 0.5 8e-34 115.2 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KHN70182.1 - 3.9e-16 58.6 0.6 4.3e-16 58.5 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KHN70182.1 - 4.9e-06 26.9 0.2 2e-05 25.0 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KHN70182.1 - 0.0016 18.3 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 KHN70182.1 - 0.0018 18.2 0.4 1.5 9.0 0.1 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KHN70182.1 - 0.0022 18.3 0.1 0.0025 18.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 KHN70182.1 - 0.013 16.1 0.1 0.014 15.9 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KHN70182.1 - 0.016 15.3 0.1 0.034 14.2 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 KHN70182.1 - 0.041 13.7 0.0 0.046 13.5 0.0 1.0 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HATPase_c PF02518.26 KHN70182.1 - 0.1 13.1 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAP_central PF04928.17 KHN70183.1 - 1.2e-90 302.8 0.0 2e-90 302.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KHN70183.1 - 1.4e-18 67.1 6.6 9.3e-17 61.2 1.8 2.6 2 1 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KHN70183.1 - 1e-12 48.2 0.0 3.6e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain IL12 PF03039.14 KHN70183.1 - 0.063 12.6 0.3 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit CBFD_NFYB_HMF PF00808.23 KHN70184.1 - 4.3e-10 39.7 0.7 6.6e-10 39.1 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KHN70184.1 - 7.2e-07 29.6 0.0 9.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KHN70184.1 - 8.2e-07 29.0 0.1 1e-06 28.7 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Peptidase_C3G PF12381.8 KHN70184.1 - 0.048 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase WD40 PF00400.32 KHN70185.1 - 1.2e-09 38.6 6.9 0.00028 21.6 0.0 7.5 8 0 0 8 8 8 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70185.1 - 7.4e-07 29.4 0.3 0.007 16.6 0.0 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KHN70185.1 - 0.55 10.3 2.3 4.9 7.3 0.1 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat SPT_ssu-like PF11779.8 KHN70186.1 - 7.8e-07 28.6 5.7 7.8e-07 28.6 5.7 1.4 1 1 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like DnaJ PF00226.31 KHN70188.1 - 3.4e-13 49.5 0.6 6.4e-13 48.6 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.13 KHN70188.1 - 0.035 14.6 4.9 0.48 10.9 1.2 2.9 2 2 0 2 2 2 0 HSCB C-terminal oligomerisation domain AAA PF00004.29 KHN70189.1 - 4.5e-11 43.3 0.0 8.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KHN70189.1 - 1e-09 38.4 0.0 8.2e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit RuvB_N PF05496.12 KHN70189.1 - 3.7e-08 33.3 0.0 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KHN70189.1 - 8.6e-06 26.1 0.1 0.00067 20.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KHN70189.1 - 9.3e-06 25.8 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KHN70189.1 - 2.2e-05 24.9 0.0 9e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KHN70189.1 - 3e-05 23.8 0.1 7e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KHN70189.1 - 5.6e-05 23.2 0.3 0.006 16.6 0.5 3.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KHN70189.1 - 6.1e-05 22.5 0.1 0.0035 16.8 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KHN70189.1 - 8.2e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KHN70189.1 - 0.00023 21.0 0.1 0.0078 16.0 0.1 2.2 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KHN70189.1 - 0.00052 20.6 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KHN70189.1 - 0.00075 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KHN70189.1 - 0.00098 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KHN70189.1 - 0.0014 18.3 0.0 0.47 10.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 KHN70189.1 - 0.0016 17.9 0.0 0.0042 16.5 0.0 1.6 1 1 1 2 2 2 1 Bacterial TniB protein Rad17 PF03215.15 KHN70189.1 - 0.0016 18.4 0.2 0.008 16.1 0.2 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 KHN70189.1 - 0.0048 17.1 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KHN70189.1 - 0.0053 17.1 0.2 0.22 11.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KHN70189.1 - 0.013 14.9 0.1 0.66 9.4 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KHN70189.1 - 0.03 13.9 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KHN70189.1 - 0.056 13.2 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rb_C PF08934.10 KHN70189.1 - 0.08 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Rb C-terminal domain Roc PF08477.13 KHN70189.1 - 0.083 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rep_fac_C PF08542.11 KHN70189.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain AAA_7 PF12775.7 KHN70189.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Hydrolase_6 PF13344.6 KHN70189.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NB-ARC PF00931.22 KHN70189.1 - 0.091 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 KHN70189.1 - 0.092 12.1 0.1 0.51 9.7 0.1 2.0 1 1 1 2 2 2 0 KaiC AAA_13 PF13166.6 KHN70189.1 - 0.13 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KHN70189.1 - 0.15 11.9 0.1 0.46 10.4 0.0 1.8 1 1 1 2 2 2 0 NTPase TsaE PF02367.17 KHN70189.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KHN70189.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.6 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 KHN70189.1 - 0.2 11.4 0.1 0.62 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KHN70190.1 - 4.5e-43 147.0 0.0 1.2e-42 145.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN70190.1 - 1.5e-31 109.0 1.4 1.4e-29 102.6 0.0 3.5 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN70190.1 - 1.9e-06 28.0 0.0 5.2e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 KHN70190.1 - 0.0058 15.5 0.5 0.024 13.4 0.0 2.1 3 0 0 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PRAI PF00697.22 KHN70190.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase AAA_22 PF13401.6 KHN70190.1 - 0.077 13.3 0.3 2.9 8.2 0.1 3.2 3 1 0 3 3 3 0 AAA domain Muskelin_N PF06588.11 KHN70191.1 - 3.7e-70 235.9 1.3 7.9e-70 234.8 1.3 1.5 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_5 PF13854.6 KHN70191.1 - 1.6e-17 63.1 2.7 0.00061 19.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 KHN70191.1 - 3.5e-16 59.0 2.8 0.00085 19.5 0.1 6.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KHN70191.1 - 2.1e-12 46.8 6.1 0.042 14.2 0.0 6.7 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KHN70191.1 - 8.6e-12 44.5 8.7 0.028 14.4 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 KHN70191.1 - 7.1e-11 41.9 0.4 0.1 12.6 0.1 5.9 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KHN70191.1 - 4.9e-10 38.8 8.6 8.8e-05 22.0 0.1 5.6 6 0 0 6 6 6 3 Kelch motif F5_F8_type_C PF00754.25 KHN70191.1 - 3.5e-07 30.4 0.0 1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain PH PF00169.29 KHN70192.1 - 0.0017 18.9 0.2 0.0045 17.5 0.2 1.8 1 0 0 1 1 1 1 PH domain HALZ PF02183.18 KHN70193.1 - 0.0012 19.1 3.0 0.0012 19.1 3.0 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIVA PF05103.13 KHN70193.1 - 0.0012 19.0 0.5 0.0024 17.9 0.5 1.5 1 0 0 1 1 1 1 DivIVA protein CPSF_A PF03178.15 KHN70193.1 - 0.0032 16.8 0.1 0.018 14.4 0.0 2.2 2 1 0 2 2 2 1 CPSF A subunit region CNH PF00780.22 KHN70193.1 - 0.0074 15.9 0.0 0.04 13.5 0.0 2.2 1 1 1 2 2 2 1 CNH domain NRBF2 PF08961.10 KHN70193.1 - 0.0083 15.8 0.3 0.018 14.7 0.3 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator LVIVD PF08309.11 KHN70193.1 - 0.018 14.4 1.2 0.097 12.0 0.1 2.3 2 0 0 2 2 2 0 LVIVD repeat ZapB PF06005.12 KHN70193.1 - 0.02 15.3 2.3 0.044 14.2 2.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 KHN70193.1 - 0.025 15.2 0.7 0.067 13.8 0.7 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 KHN70193.1 - 0.038 13.8 1.3 0.12 12.2 1.3 1.8 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 KHN70193.1 - 0.049 12.5 0.3 0.091 11.6 0.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup160 PF11715.8 KHN70193.1 - 0.13 10.9 0.1 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PikAIV_N PF18605.1 KHN70193.1 - 0.14 11.8 1.4 0.3 10.7 1.4 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF3450 PF11932.8 KHN70193.1 - 0.54 9.5 4.1 1.2 8.4 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.6 KHN70193.1 - 0.61 10.2 4.1 5.7 7.1 1.6 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain Cse1 PF08506.10 KHN70194.1 - 3.6e-05 22.8 5.9 0.019 13.8 5.9 3.6 1 1 0 1 1 1 1 Cse1 UPF0121 PF03661.13 KHN70194.1 - 0.06 12.7 0.2 0.18 11.2 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) RasGEF_N PF00618.20 KHN70194.1 - 0.13 12.6 0.3 0.39 11.0 0.3 1.9 1 0 0 1 1 1 0 RasGEF N-terminal motif Leo1 PF04004.13 KHN70195.1 - 0.0013 18.6 0.1 0.0027 17.6 0.0 1.5 1 1 1 2 2 2 1 Leo1-like protein Ribosomal_L5_C PF00673.21 KHN70196.1 - 3.7e-21 75.1 0.1 6.7e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KHN70196.1 - 4.4e-19 68.6 0.2 8.6e-19 67.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 MMPL PF03176.15 KHN70197.1 - 0.12 11.3 0.5 0.13 11.1 0.5 1.2 1 0 0 1 1 1 0 MMPL family LRR_4 PF12799.7 KHN70198.1 - 1.1e-10 41.5 8.6 0.0083 16.5 0.0 6.2 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KHN70198.1 - 6.6e-06 25.8 11.1 0.3 10.9 0.3 6.1 4 2 2 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 KHN70198.1 - 0.006 17.0 14.5 51 5.0 0.8 8.1 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KHN70198.1 - 0.038 14.1 8.6 89 3.5 0.2 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Lactamase_B PF00753.27 KHN70199.1 - 1e-06 28.9 0.1 0.0041 17.1 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KHN70199.1 - 0.001 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HAGH_C PF16123.5 KHN70199.1 - 0.07 13.6 0.8 0.29 11.7 0.8 2.0 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Beta_lactamase3 PF17030.5 KHN70200.1 - 8e-67 224.6 5.2 1.5e-66 223.7 0.0 2.9 3 0 0 3 3 3 1 Putative beta-lactamase-like family Lactamase_B_6 PF16661.5 KHN70200.1 - 6.4e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Pkinase PF00069.25 KHN70202.1 - 1.7e-54 185.0 2.1 2.4e-52 177.9 2.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70202.1 - 2.1e-27 96.1 0.8 1.4e-26 93.4 0.2 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KHN70202.1 - 0.0066 15.4 0.0 0.15 10.9 0.0 2.2 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 KHN70202.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KHN70202.1 - 0.021 14.4 0.0 0.22 11.1 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KHN70202.1 - 0.027 13.3 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KHN70202.1 - 0.027 13.8 0.0 0.084 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2724 PF10893.8 KHN70202.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Adap_comp_sub PF00928.21 KHN70203.1 - 2.2e-11 43.6 1.2 4.6e-09 36.0 1.2 2.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family CooT PF10133.9 KHN70203.1 - 0.037 14.3 0.1 0.094 13.0 0.1 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT SHD1 PF03983.12 KHN70203.1 - 0.057 13.3 0.1 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 SLA1 homology domain 1, SHD1 RRM_1 PF00076.22 KHN70204.1 - 3.7e-16 58.7 0.0 4.3e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KHN70204.1 - 7.9e-06 25.5 0.0 9.3e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KHN70204.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KHN70204.1 - 0.034 14.2 0.0 0.099 12.7 0.0 1.7 1 1 0 1 1 1 0 Limkain b1 Cpn60_TCP1 PF00118.24 KHN70205.1 - 9.8e-111 370.8 8.7 1.1e-110 370.6 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 KHN70206.1 - 3.2e-53 180.8 0.6 5.2e-53 180.1 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70206.1 - 9.5e-23 80.8 0.8 1.3e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KHN70206.1 - 0.00016 21.7 0.0 0.03 14.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 KHN70206.1 - 0.0025 17.5 3.0 0.13 11.9 0.0 2.7 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 KIAA1328 PF15369.6 KHN70206.1 - 0.0031 17.4 0.6 0.0031 17.4 0.6 2.3 3 0 0 3 3 3 1 Uncharacterised protein KIAA1328 Kinase-like PF14531.6 KHN70206.1 - 0.0036 16.7 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KHN70206.1 - 0.0067 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KHN70206.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTS PF04204.16 KHN70207.1 - 0.02 13.8 0.3 0.038 12.9 0.3 1.4 1 0 0 1 1 1 0 Homoserine O-succinyltransferase DUF5595 PF18077.1 KHN70207.1 - 0.037 14.1 4.2 0.058 13.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) ZapB PF06005.12 KHN70207.1 - 0.46 11.0 5.2 1.6 9.2 5.1 1.8 1 1 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 KHN70207.1 - 2.1 8.6 6.1 0.67 10.2 1.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper CIAPIN1 PF05093.13 KHN70208.1 - 6.4e-15 55.5 12.4 1.3e-13 51.3 3.8 2.4 1 1 2 3 3 3 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis PTP2 PF17022.5 KHN70208.1 - 2.9 7.5 9.9 4.6 6.8 9.9 1.5 1 1 0 1 1 1 0 Polar tube protein 2 from Microsporidia PC_rep PF01851.22 KHN70209.1 - 1.5e-23 82.0 12.9 0.00029 21.1 0.1 9.0 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KHN70209.1 - 2.6e-11 43.8 0.0 9.1e-08 32.4 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KHN70209.1 - 0.00035 20.6 0.2 3.3 8.2 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 KHN70209.1 - 0.011 16.3 0.7 7.6 7.2 0.0 3.4 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 KHN70209.1 - 0.036 14.1 1.8 0.9 9.6 0.0 3.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SPOB_a PF14689.6 KHN70209.1 - 0.18 11.6 0.2 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain Nucleoporin2 PF04096.14 KHN70211.1 - 6.4e-13 49.1 0.1 1.1e-12 48.4 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase TFIIA_gamma_C PF02751.14 KHN70212.1 - 1.1e-12 47.9 1.8 1.6e-12 47.4 1.8 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KHN70212.1 - 4e-10 39.5 0.0 5.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Arg_decarbox_C PF17944.1 KHN70212.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension TypeIII_RM_meth PF12564.8 KHN70212.1 - 0.13 12.4 0.5 0.23 11.6 0.5 1.4 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit GSHPx PF00255.19 KHN70213.1 - 2.5e-26 91.4 1.1 6.7e-26 90.0 1.1 1.7 1 1 0 1 1 1 1 Glutathione peroxidase Sec1 PF00995.23 KHN70214.1 - 3.6e-45 155.3 8.2 5.8e-45 154.6 8.2 1.3 1 0 0 1 1 1 1 Sec1 family GH101_N PF17995.1 KHN70214.1 - 0.053 13.2 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase N-terminal Paz_1 PF18349.1 KHN70214.1 - 0.28 11.2 2.2 14 5.7 0.0 3.4 3 0 0 3 3 3 0 PAZ domain Myb_DNA-bind_6 PF13921.6 KHN70215.1 - 1.1e-19 70.4 0.1 2.9e-13 49.8 0.1 2.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KHN70215.1 - 1.1e-18 67.1 1.0 7.5e-12 45.3 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KHN70215.1 - 0.001 19.1 0.0 0.036 14.1 0.0 2.3 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain AdoMet_dc PF02675.15 KHN70215.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase Ras PF00071.22 KHN70216.1 - 3.8e-39 133.9 0.0 4.6e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN70216.1 - 9.7e-15 54.8 0.0 1.4e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN70216.1 - 2.3e-09 37.0 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KHN70216.1 - 0.0009 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KHN70216.1 - 0.0051 16.9 0.0 0.0069 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KHN70216.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit XPG_I PF00867.18 KHN70217.1 - 0.0003 21.1 0.0 0.00083 19.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region TAP42 PF04177.12 KHN70218.1 - 1.5e-05 24.3 8.3 0.0076 15.4 8.3 2.8 1 1 0 1 1 1 1 TAP42-like family Plus-3 PF03126.18 KHN70219.1 - 9.9e-14 51.8 0.1 2.2e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Plus-3 domain 8TM_micro PF17028.5 KHN70220.1 - 2.4e-59 201.1 25.3 2.9e-59 200.9 25.3 1.0 1 0 0 1 1 1 1 8TM Microsporidial transmembrane domain Proteasome PF00227.26 KHN70221.1 - 2.2e-34 118.6 0.0 2.7e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase PF00702.26 KHN70222.1 - 6.2e-22 78.9 0.0 9.3e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KHN70222.1 - 1.5e-19 70.2 0.1 1.5e-19 70.2 0.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KHN70222.1 - 9.2e-09 35.3 0.1 2.3e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KHN70222.1 - 0.00015 21.6 0.3 0.14 11.9 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KHN70222.1 - 0.0068 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KHN70222.1 - 0.041 14.0 0.3 0.23 11.5 0.1 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ImmE5 PF11480.8 KHN70223.1 - 0.079 13.5 0.4 19 5.8 0.4 2.4 2 0 0 2 2 2 0 Colicin-E5 Imm protein zf-C2H2_jaz PF12171.8 KHN70224.1 - 5.5e-08 32.9 1.4 5.5e-08 32.9 1.4 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KHN70224.1 - 0.00085 19.6 0.3 0.0022 18.3 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KHN70224.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.3 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KHN70224.1 - 0.065 13.6 0.3 0.083 13.2 0.3 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DnaJ PF00226.31 KHN70225.1 - 3.8e-11 42.9 0.8 6e-11 42.3 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1689 PF07954.11 KHN70225.1 - 2.5 8.5 4.8 0.84 10.0 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1689) AAA PF00004.29 KHN70226.1 - 2.5e-17 63.6 0.0 4.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KHN70226.1 - 3.3e-15 56.2 0.0 7.3e-13 48.6 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KHN70226.1 - 2.1e-09 37.8 0.2 0.00024 21.4 0.0 2.9 2 2 1 3 3 3 2 AAA domain Rep_fac_C PF08542.11 KHN70226.1 - 2.9e-09 37.2 0.2 1.7e-08 34.7 0.0 2.4 3 0 0 3 3 2 1 Replication factor C C-terminal domain RuvB_N PF05496.12 KHN70226.1 - 4.3e-07 29.8 0.0 1.3e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KHN70226.1 - 6.7e-07 28.9 0.2 2e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KHN70226.1 - 1.2e-06 28.6 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KHN70226.1 - 1.7e-06 28.5 0.2 0.00025 21.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KHN70226.1 - 2.2e-06 27.5 1.2 2.3e-05 24.2 0.5 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KHN70226.1 - 2.6e-06 27.8 0.0 1.2e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KHN70226.1 - 4e-06 26.9 0.1 3.2e-05 23.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 KHN70226.1 - 8.6e-06 25.7 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 KHN70226.1 - 5.1e-05 23.1 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KHN70226.1 - 0.00017 21.8 0.1 0.00079 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KHN70226.1 - 0.00023 20.8 0.0 0.00055 19.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 KHN70226.1 - 0.00023 21.7 0.1 0.004 17.7 0.0 2.5 1 1 2 3 3 3 1 AAA domain AAA_11 PF13086.6 KHN70226.1 - 0.00036 20.4 0.1 0.0016 18.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KHN70226.1 - 0.0005 20.4 0.7 0.065 13.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KHN70226.1 - 0.00082 19.3 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain PIF1 PF05970.14 KHN70226.1 - 0.00096 18.4 0.3 0.068 12.3 0.2 2.3 1 1 1 2 2 2 1 PIF1-like helicase DEAD PF00270.29 KHN70226.1 - 0.0013 18.6 0.7 0.024 14.4 0.1 2.6 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.6 KHN70226.1 - 0.0039 17.4 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 KHN70226.1 - 0.0056 15.8 0.0 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 MCM P-loop domain AAA_assoc_2 PF16193.5 KHN70226.1 - 0.0062 16.8 0.2 0.04 14.3 0.0 2.4 2 1 1 3 3 2 1 AAA C-terminal domain ATPase_2 PF01637.18 KHN70226.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Thymidylate_kin PF02223.17 KHN70226.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase TniB PF05621.11 KHN70226.1 - 0.024 14.1 0.0 0.47 9.8 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 KHN70226.1 - 0.025 14.5 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 KHN70226.1 - 0.031 13.9 0.0 0.81 9.3 0.0 2.5 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 KHN70226.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.6 1 1 0 1 1 1 0 RsgA GTPase AAA_6 PF12774.7 KHN70226.1 - 0.037 13.0 0.0 0.078 11.9 0.0 1.6 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_17 PF13207.6 KHN70226.1 - 0.056 13.9 0.2 0.17 12.3 0.1 2.0 2 1 0 2 2 1 0 AAA domain SNF2_N PF00176.23 KHN70226.1 - 0.061 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain NTPase_1 PF03266.15 KHN70226.1 - 0.071 13.0 0.2 0.3 11.0 0.0 2.0 1 1 1 2 2 2 0 NTPase DUF815 PF05673.13 KHN70226.1 - 0.076 12.2 0.0 0.2 10.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KHN70226.1 - 0.081 12.7 0.2 5 6.8 0.0 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 KHN70226.1 - 0.096 12.4 0.2 0.54 10.0 0.1 2.3 2 1 0 2 2 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KHN70226.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KHN70226.1 - 0.11 11.8 0.1 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KHN70226.1 - 0.12 12.9 0.2 0.91 10.0 0.1 2.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KHN70226.1 - 0.15 11.6 0.3 1.3 8.5 0.2 2.1 1 1 1 2 2 2 0 AAA domain GIT_SHD PF08518.11 KHN70228.1 - 2.1e-06 27.2 0.2 0.00011 21.7 0.1 2.6 2 0 0 2 2 2 1 Spa2 homology domain (SHD) of GIT TetR_C_24 PF17932.1 KHN70228.1 - 0.023 15.0 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Occludin_ELL PF07303.13 KHN70228.1 - 3.1 8.6 7.9 0.28 11.9 0.6 2.8 4 0 0 4 4 4 0 Occludin homology domain GATA PF00320.27 KHN70229.1 - 5.7e-16 57.8 6.8 5.7e-16 57.8 6.8 2.8 2 1 0 2 2 2 1 GATA zinc finger ArfGap PF01412.18 KHN70229.1 - 0.00061 19.9 10.9 0.01 15.9 1.0 3.0 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KHN70230.1 - 9e-36 121.5 0.7 4.1e-13 49.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KHN70230.1 - 0.00015 21.4 0.0 0.064 12.9 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KHN70230.1 - 0.00025 21.0 0.0 0.69 10.0 0.0 3.3 3 1 0 3 3 3 2 RNA binding domain RRM_7 PF16367.5 KHN70230.1 - 0.00048 20.2 0.1 3.3 7.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KHN70230.1 - 0.0016 18.3 0.0 0.14 12.0 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KHN70230.1 - 0.0064 16.3 0.1 0.029 14.2 0.1 2.0 1 1 1 2 2 2 1 Rrp7 RRM-like N-terminal domain NIR_SIR PF01077.22 KHN70230.1 - 0.044 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Limkain-b1 PF11608.8 KHN70230.1 - 0.059 13.5 0.1 1.2 9.3 0.1 2.6 2 1 0 2 2 2 0 Limkain b1 SET_assoc PF11767.8 KHN70230.1 - 0.07 12.8 0.5 3.1 7.5 0.1 3.3 4 1 0 4 4 4 0 Histone lysine methyltransferase SET associated WD40 PF00400.32 KHN70231.1 - 3.3e-19 68.9 1.0 8.9e-06 26.4 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Sof1 PF04158.14 KHN70231.1 - 5.3e-14 52.2 5.4 5.3e-14 52.2 5.4 2.2 2 0 0 2 2 2 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KHN70231.1 - 4.4e-05 23.7 0.0 0.023 15.0 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 KHN70231.1 - 0.036 13.7 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 CNH domain Bac_export_2 PF01312.19 KHN70232.1 - 0.2 10.8 2.2 0.24 10.6 2.2 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF1863 PF08937.11 KHN70233.1 - 0.029 14.7 0.1 0.033 14.5 0.1 1.2 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Nnf1 PF03980.14 KHN70234.1 - 0.01 16.2 2.9 0.017 15.5 0.9 2.5 2 1 1 3 3 3 0 Nnf1 Abi_C PF14355.6 KHN70234.1 - 0.052 13.6 0.1 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Abortive infection C-terminus FlxA PF14282.6 KHN70234.1 - 0.067 13.2 1.3 0.49 10.4 0.2 2.3 2 0 0 2 2 2 0 FlxA-like protein Taxilin PF09728.9 KHN70234.1 - 0.13 11.4 11.0 0.049 12.8 1.4 2.5 3 0 0 3 3 3 0 Myosin-like coiled-coil protein TPR_MLP1_2 PF07926.12 KHN70234.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Sipho_Gp157 PF05565.11 KHN70234.1 - 0.32 11.0 10.6 0.44 10.6 3.4 2.8 2 1 1 3 3 3 0 Siphovirus Gp157 DUF1664 PF07889.12 KHN70234.1 - 0.48 10.5 4.6 0.51 10.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KHN70234.1 - 3.2 8.4 6.6 0.64 10.7 0.9 2.5 2 1 0 2 2 2 0 Initiation control protein YabA U1snRNP70_N PF12220.8 KHN70234.1 - 3.7 8.3 6.0 2.5 8.8 0.2 2.4 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Seryl_tRNA_N PF02403.22 KHN70234.1 - 5.3 7.3 10.4 0.28 11.4 0.5 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 KHN70234.1 - 7.6 6.5 10.6 0.39 10.7 3.4 2.5 2 1 1 3 3 3 0 Prefoldin subunit APG6_N PF17675.1 KHN70234.1 - 8.9 6.8 8.8 34 5.0 8.8 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region LNS2 PF08235.13 KHN70235.1 - 9.1e-94 313.2 0.0 1.3e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KHN70235.1 - 9.2e-29 99.4 0.1 2.1e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region DUF4479 PF14794.6 KHN70235.1 - 0.00091 19.0 0.1 0.004 17.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4479) Acid_phosphat_B PF03767.14 KHN70235.1 - 0.0032 17.1 0.1 0.011 15.4 0.1 1.8 1 1 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) SOBP PF15279.6 KHN70236.1 - 0.007 17.0 8.8 0.0086 16.7 8.8 1.0 1 0 0 1 1 1 1 Sine oculis-binding protein CDC45 PF02724.14 KHN70236.1 - 0.14 10.4 13.7 0.15 10.3 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KHN70236.1 - 1.4 7.6 6.4 1.6 7.4 6.4 1.2 1 0 0 1 1 1 0 Presenilin Pal1 PF08316.11 KHN70236.1 - 3.1 8.5 6.8 7.3 7.3 6.8 1.7 1 1 0 1 1 1 0 Pal1 cell morphology protein RIH_assoc PF08454.11 KHN70237.1 - 0.04 13.8 1.0 0.085 12.7 1.0 1.5 1 0 0 1 1 1 0 RyR and IP3R Homology associated Pox_polyA_pol PF03296.13 KHN70237.1 - 0.11 12.4 3.8 2.2 8.2 0.1 2.4 2 1 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain PSI_PsaF PF02507.15 KHN70237.1 - 0.12 12.2 0.8 0.45 10.3 0.5 2.0 1 1 0 2 2 2 0 Photosystem I reaction centre subunit III ZapD PF07072.11 KHN70237.1 - 0.56 9.9 5.1 3.5 7.3 0.5 2.2 1 1 1 2 2 2 0 Cell division protein Fzo_mitofusin PF04799.13 KHN70237.1 - 2.3 7.8 6.1 1.4 8.4 2.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region Glyco_hydro_99 PF16317.5 KHN70238.1 - 0.0071 15.5 0.3 0.015 14.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 99 Mab-21 PF03281.14 KHN70238.1 - 0.015 14.6 0.4 0.026 13.8 0.4 1.4 1 0 0 1 1 1 0 Mab-21 protein DUF1870 PF08965.10 KHN70238.1 - 0.041 13.9 0.5 0.041 13.9 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) MICSWaP PF17018.5 KHN70239.1 - 1.1e-31 109.9 0.1 1.5e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Spore wall protein IPTL-CTERM PF18203.1 KHN70239.1 - 0.38 10.7 2.2 0.59 10.1 2.2 1.2 1 0 0 1 1 1 0 IPTL-CTERM motif Ran_BP1 PF00638.18 KHN70240.1 - 1.2e-18 67.6 0.4 2.2e-18 66.7 0.4 1.4 1 0 0 1 1 1 1 RanBP1 domain MRP-S23 PF10484.9 KHN70240.1 - 3.7 7.8 10.9 1.9 8.8 8.1 1.9 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 DUF4781 PF16013.5 KHN70241.1 - 0.028 13.2 1.0 0.043 12.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Branch PF02485.21 KHN70241.1 - 0.068 12.7 0.5 0.74 9.3 0.0 2.0 2 0 0 2 2 2 0 Core-2/I-Branching enzyme Ribosomal_S21 PF01165.20 KHN70241.1 - 0.11 12.2 2.2 4.5 7.1 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S21 AIM24 PF01987.17 KHN70242.1 - 0.085 12.6 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 CLTH PF10607.9 KHN70243.1 - 1.2e-06 28.5 1.3 3.3e-06 27.0 1.3 1.8 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF4363 PF14276.6 KHN70243.1 - 0.041 14.0 1.1 0.13 12.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Cauli_AT PF03233.13 KHN70243.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Aphid transmission protein HSP70 PF00012.20 KHN70244.1 - 3.2e-99 332.8 1.8 4.2e-99 332.4 1.8 1.1 1 0 0 1 1 1 1 Hsp70 protein MgtE_N PF03448.17 KHN70245.1 - 6e-06 26.8 3.6 9.6e-06 26.1 0.9 2.4 2 1 0 3 3 3 1 MgtE intracellular N domain FliG_M PF14841.6 KHN70245.1 - 0.0029 17.8 1.0 3.5 7.9 0.1 3.7 2 1 2 4 4 4 2 FliG middle domain DUF4301 PF14134.6 KHN70245.1 - 0.12 11.2 4.2 0.069 11.9 2.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) FliG_N PF14842.6 KHN70245.1 - 0.32 11.6 2.7 22 5.6 0.0 3.6 2 1 2 5 5 5 0 FliG N-terminal domain Ribosomal_S8e PF01201.22 KHN70247.1 - 9.6e-40 135.9 4.9 1.2e-39 135.6 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e PHD PF00628.29 KHN70248.1 - 3.5e-08 33.2 4.8 7.1e-08 32.2 3.6 2.0 2 0 0 2 2 2 1 PHD-finger Ribosomal_S25 PF03297.15 KHN70248.1 - 0.024 14.9 0.0 0.043 14.0 0.0 1.4 1 1 0 1 1 1 0 S25 ribosomal protein FtsK_gamma PF09397.10 KHN70248.1 - 0.057 13.2 0.1 0.095 12.5 0.1 1.4 1 1 0 1 1 1 0 Ftsk gamma domain HTH_27 PF13463.6 KHN70248.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain PHD_2 PF13831.6 KHN70248.1 - 0.15 11.6 6.8 0.32 10.6 3.9 2.4 2 1 0 2 2 2 0 PHD-finger Zn_ribbon_recom PF13408.6 KHN70248.1 - 0.93 10.1 8.8 1.6 9.3 5.4 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L35Ae PF01247.18 KHN70249.1 - 1.1e-23 83.2 0.3 1.3e-23 82.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KHN70249.1 - 0.0047 17.1 0.0 3 8.1 0.1 2.9 2 1 0 2 2 2 2 RimM N-terminal domain XTBD PF11952.8 KHN70250.1 - 0.08 12.7 0.2 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD MAD PF05557.13 KHN70251.1 - 1.8e-16 59.7 0.3 1.8e-16 59.7 0.3 2.2 1 1 0 2 2 2 1 Mitotic checkpoint protein SSXT PF05030.12 KHN70251.1 - 0.0079 15.8 1.7 0.018 14.6 0.8 2.2 1 1 1 2 2 2 1 SSXT protein (N-terminal region) Chordopox_E11 PF06138.12 KHN70251.1 - 0.084 13.2 0.3 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 Chordopoxvirus E11 protein Hormone_3 PF00159.18 KHN70251.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide Cnn_1N PF07989.11 KHN70251.1 - 0.28 11.4 8.3 1 9.5 0.4 2.7 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 KHN70251.1 - 8.9 6.3 7.4 17 5.4 0.4 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Suf PF05843.14 KHN70252.1 - 7.4e-11 42.6 8.1 3.2e-10 40.5 0.5 3.0 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 KHN70252.1 - 0.048 13.9 1.8 1.2 9.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 KHN70253.1 - 8.1e-43 146.7 0.7 9.7e-43 146.5 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KHN70253.1 - 9.5e-16 57.9 0.0 4.7e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KHN70253.1 - 1.4e-12 48.0 0.6 1.2e-11 45.0 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KHN70253.1 - 1.8e-05 24.5 0.4 0.0015 18.2 0.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KHN70253.1 - 0.00024 20.3 0.4 2.2 7.3 0.0 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KHN70253.1 - 0.00087 18.5 0.4 1.2 8.1 0.0 3.6 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 KHN70253.1 - 0.0044 15.8 0.1 7.3 5.2 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 KHN70253.1 - 0.0079 15.5 0.4 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_7 PF13241.6 KHN70253.1 - 0.012 16.1 0.1 0.05 14.0 0.2 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KHN70253.1 - 0.012 14.7 0.1 2.8 6.9 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein K_oxygenase PF13434.6 KHN70253.1 - 0.017 14.3 0.1 11 5.1 0.0 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Bclx_interact PF08945.10 KHN70253.1 - 0.12 12.2 0.7 0.24 11.2 0.7 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain DUF5089 PF17002.5 KHN70254.1 - 5.5e-57 192.8 15.6 6.7e-57 192.5 15.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) DUF2795 PF11387.8 KHN70254.1 - 0.0042 17.2 0.3 0.013 15.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) APG6 PF04111.12 KHN70254.1 - 0.023 14.6 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Apg6 BARA domain EMP24_GP25L PF01105.24 KHN70255.1 - 1.7e-08 34.6 1.1 2.2e-08 34.2 1.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3203 PF11462.8 KHN70255.1 - 0.038 14.2 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) TRAPP PF04051.16 KHN70256.1 - 9.7e-08 31.8 0.1 7.1e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Archease PF01951.16 KHN70257.1 - 2.4e-18 66.7 0.1 3.3e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) FlgN PF05130.12 KHN70258.1 - 0.011 16.2 1.9 0.016 15.7 0.1 1.9 2 0 0 2 2 2 0 FlgN protein Kinesin_assoc PF16183.5 KHN70258.1 - 0.02 15.0 4.4 0.03 14.5 4.4 1.2 1 0 0 1 1 1 0 Kinesin-associated DASH_Dam1 PF08653.10 KHN70258.1 - 0.37 10.6 1.9 0.38 10.6 0.1 1.8 2 1 0 2 2 2 0 DASH complex subunit Dam1 Rad17 PF03215.15 KHN70259.1 - 0.0058 16.6 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain CLTH PF10607.9 KHN70260.1 - 1.6e-10 41.0 3.5 3.6e-10 39.9 3.5 1.6 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KHN70260.1 - 0.00017 21.5 0.2 0.00051 19.9 0.2 1.9 1 0 0 1 1 1 1 LisH Fer4_12 PF13353.6 KHN70260.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain LSM PF01423.22 KHN70261.1 - 1.9e-05 24.2 0.2 0.00012 21.7 0.2 2.0 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 KHN70261.1 - 0.0025 17.4 0.0 0.0028 17.3 0.0 1.1 1 0 0 1 1 1 1 Hfq protein EHD_N PF16880.5 KHN70261.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 N-terminal EH-domain containing protein Sel1 PF08238.12 KHN70262.1 - 7.8e-09 35.9 8.9 0.0084 16.8 0.1 4.0 3 0 0 3 3 3 3 Sel1 repeat TPR_11 PF13414.6 KHN70262.1 - 5 6.9 11.8 0.55 10.0 0.8 4.3 5 0 0 5 5 5 0 TPR repeat Gti1_Pac2 PF09729.9 KHN70263.1 - 9.9e-34 117.0 1.2 1.2e-29 103.7 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family NAC PF01849.18 KHN70264.1 - 0.0004 20.3 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 NAC domain HBS1_N PF08938.10 KHN70264.1 - 0.014 15.7 1.6 0.042 14.2 1.6 2.0 1 1 0 1 1 1 0 HBS1 N-terminus PPTA PF01239.22 KHN70265.1 - 7.1e-18 63.7 1.3 1.8e-08 33.8 0.1 3.1 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat Pfg27 PF09216.10 KHN70265.1 - 0.016 15.0 1.1 0.11 12.3 0.1 2.6 3 0 0 3 3 3 0 Pfg27 DUF5319 PF17252.2 KHN70265.1 - 3.7 7.8 6.9 0.22 11.8 0.7 2.2 3 1 0 3 3 3 0 Family of unknown function (DUF5319) BOP1NT PF08145.12 KHN70266.1 - 4.8e-05 23.4 5.8 6.3e-05 23.0 0.2 2.2 1 1 1 2 2 2 2 BOP1NT (NUC169) domain ubiquitin PF00240.23 KHN70267.1 - 2.1e-33 113.9 0.7 3.2e-33 113.3 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KHN70267.1 - 2.4e-16 59.3 0.6 3.4e-16 58.8 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KHN70267.1 - 5.1e-05 23.6 0.1 0.00021 21.7 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KHN70267.1 - 0.001 19.2 0.4 0.0023 18.0 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KHN70267.1 - 0.0025 17.7 0.2 0.0046 16.9 0.0 1.5 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 KHN70267.1 - 0.0059 17.1 0.3 0.008 16.7 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 KHN70267.1 - 0.011 15.8 1.0 3.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KHN70267.1 - 0.014 15.8 0.1 0.025 14.9 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain Ribosomal_S27 PF01599.19 KHN70267.1 - 0.019 15.2 6.3 0.039 14.1 6.3 1.6 1 0 0 1 1 1 0 Ribosomal protein S27a zf-HIT PF04438.16 KHN70267.1 - 3.7 7.5 9.9 16 5.4 10.0 1.9 1 1 0 1 1 1 0 HIT zinc finger Helicase_C_2 PF13307.6 KHN70268.1 - 2.6e-51 174.2 0.1 8.1e-51 172.6 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KHN70268.1 - 6.1e-49 166.0 0.4 1.1e-48 165.1 0.4 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 KHN70268.1 - 0.00038 20.3 0.6 0.0072 16.1 0.6 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KHN70268.1 - 0.0015 18.5 0.0 0.013 15.5 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KHN70268.1 - 0.0055 16.5 0.1 0.052 13.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain HBB PF06777.11 KHN70268.1 - 0.023 14.4 0.0 0.059 13.0 0.0 1.6 1 1 0 1 1 1 0 Helical and beta-bridge domain HSP90 PF00183.18 KHN70269.1 - 1.7e-135 452.9 23.5 2.2e-135 452.5 23.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 KHN70269.1 - 1.3e-11 44.4 0.0 4e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KHN70269.1 - 8.3e-10 39.2 0.0 1.9e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EP400_N PF15790.5 KHN70269.1 - 0.1 11.4 0.1 0.1 11.4 0.1 2.0 2 0 0 2 2 2 0 E1A-binding protein p400, N-terminal DUF1788 PF08747.11 KHN70269.1 - 0.75 9.8 3.6 34 4.4 0.0 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF1788) NUC173 PF08161.12 KHN70270.1 - 0.00084 19.1 0.0 0.016 14.9 0.0 3.0 2 0 0 2 2 2 1 NUC173 domain DUF1798 PF08807.10 KHN70270.1 - 0.16 12.1 0.5 2.3 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) PI3_PI4_kinase PF00454.27 KHN70271.1 - 7.1e-44 150.5 0.2 2.3e-43 148.8 0.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KHN70271.1 - 3.9e-09 36.2 0.0 1.4e-08 34.4 0.0 2.1 1 0 0 1 1 1 1 FATC domain L71 PF02448.15 KHN70271.1 - 0.019 15.4 0.4 0.12 12.8 0.4 2.4 1 0 0 1 1 1 0 L71 family TPR_19 PF14559.6 KHN70271.1 - 0.045 14.3 0.2 0.15 12.6 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KHN70271.1 - 0.076 13.7 0.1 0.36 11.6 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KHN70271.1 - 0.084 13.1 0.2 0.82 10.0 0.2 2.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KHN70271.1 - 0.11 12.7 0.2 0.51 10.6 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Clr5 PF14420.6 KHN70271.1 - 0.13 12.5 0.0 0.67 10.2 0.0 2.3 1 0 0 1 1 1 0 Clr5 domain SPC25 PF06703.11 KHN70272.1 - 2.1e-25 89.4 2.3 2.8e-25 89.0 2.3 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF1951 PF09188.10 KHN70272.1 - 0.0041 17.1 0.9 0.012 15.6 0.4 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1951) Frag1 PF10277.9 KHN70272.1 - 0.018 14.6 0.3 0.023 14.3 0.3 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF3938 PF13074.6 KHN70272.1 - 0.1 12.9 0.5 0.17 12.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) MCM PF00493.23 KHN70273.1 - 3.7e-99 330.3 0.0 6.4e-99 329.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN70273.1 - 2.1e-31 108.4 1.5 4.2e-31 107.4 1.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KHN70273.1 - 2.7e-24 85.4 1.1 8.6e-24 83.8 1.1 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KHN70273.1 - 6.4e-09 36.3 0.9 3.3e-08 34.1 0.3 2.6 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 KHN70273.1 - 1.2e-06 28.6 0.0 4.6e-06 26.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KHN70273.1 - 1.8e-06 27.5 0.1 4e-05 23.1 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KHN70273.1 - 0.0011 18.9 0.0 0.0052 16.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) tRNA_anti-codon PF01336.25 KHN70273.1 - 0.0044 17.0 0.1 0.3 11.1 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain Sigma54_activat PF00158.26 KHN70273.1 - 0.0096 15.6 0.1 0.74 9.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain DUF87 PF01935.17 KHN70273.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain KH_1 PF00013.29 KHN70274.1 - 1.6e-06 27.8 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 KH domain ABC_tran_CTD PF16326.5 KHN70274.1 - 0.086 13.1 0.2 17 5.7 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain AceK PF06315.11 KHN70274.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) NTF2 PF02136.20 KHN70275.1 - 7.4e-07 29.8 0.3 1e-06 29.3 0.3 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain FYRN PF05964.14 KHN70276.1 - 5.4e-14 51.8 0.4 1.6e-13 50.3 0.4 1.8 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KHN70276.1 - 0.0063 16.7 0.1 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 F/Y rich C-terminus NINJA_B PF16136.5 KHN70276.1 - 0.76 10.2 5.6 2.3 8.6 5.5 1.8 1 1 0 1 1 1 0 Putative nuclear localisation signal DUF1833 PF08875.11 KHN70277.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) DUF357 PF04010.13 KHN70277.1 - 0.11 12.5 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) THOC7 PF05615.13 KHN70277.1 - 0.13 12.5 0.9 0.31 11.3 0.4 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Fib_alpha PF08702.10 KHN70277.1 - 1.1 9.4 5.2 16 5.7 0.1 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Homeodomain PF00046.29 KHN70278.1 - 1.1e-09 38.0 0.5 2.2e-09 37.0 0.5 1.5 1 0 0 1 1 1 1 Homeodomain Thump_like PF18096.1 KHN70278.1 - 0.036 14.0 0.1 1.2 9.2 0.1 2.3 1 1 0 1 1 1 0 THUMP domain-like tRNA-synt_1c PF00749.21 KHN70279.1 - 1.2e-97 326.6 0.1 2e-97 325.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KHN70279.1 - 2.5e-35 121.9 0.6 4.5e-35 121.1 0.6 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DNA_ligase_A_M PF01068.21 KHN70280.1 - 1.8e-62 210.6 2.3 2.9e-62 209.9 2.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KHN70280.1 - 1.4e-34 119.9 0.2 2.6e-34 119.0 0.2 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KHN70280.1 - 2.2e-22 79.5 0.0 4.1e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KHN70280.1 - 4e-06 27.2 2.9 6.7e-06 26.5 2.9 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 KHN70280.1 - 0.012 15.5 0.9 0.12 12.2 0.9 2.2 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Baculo_LEF5 PF04838.12 KHN70280.1 - 0.028 14.5 0.9 0.095 12.7 0.2 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 Sec23_trunk PF04811.15 KHN70281.1 - 1.2e-15 57.7 0.0 1.2e-14 54.5 0.0 2.4 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 KHN70281.1 - 2.8e-12 46.5 1.2 6.1e-12 45.4 1.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 KHN70281.1 - 1.6e-08 34.3 0.0 3.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KHN70281.1 - 8.8e-07 29.6 0.0 2.2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KHN70281.1 - 0.0048 16.8 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Cnd1 PF12717.7 KHN70282.1 - 1.4e-15 57.7 9.5 1.1e-12 48.2 0.6 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KHN70282.1 - 2.3e-06 27.4 3.4 0.79 10.1 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KHN70282.1 - 2.4e-06 27.9 0.3 0.74 10.3 0.0 4.1 3 1 1 4 4 4 3 HEAT repeats Nipped-B_C PF12830.7 KHN70282.1 - 0.0053 16.7 0.1 0.022 14.7 0.0 2.1 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus TIP120 PF08623.10 KHN70282.1 - 0.11 12.2 4.8 0.21 11.4 0.4 3.3 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Nucleocapsid-N PF11030.8 KHN70282.1 - 0.22 11.4 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Nucleocapsid protein N TAFII28 PF04719.14 KHN70283.1 - 9.5e-33 112.2 0.0 1.4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region MIF4G PF02854.19 KHN70284.1 - 0.0097 15.6 0.1 0.076 12.6 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain DIM1 PF02966.16 KHN70285.1 - 6.1e-39 132.8 0.3 6.9e-39 132.7 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 ArAE_1_C PF11728.8 KHN70286.1 - 0.11 12.4 0.7 0.18 11.8 0.4 1.4 1 1 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Cnd2 PF05786.14 KHN70287.1 - 1.8e-50 172.4 8.5 2.5e-28 99.2 1.9 4.7 2 2 2 4 4 4 4 Condensin complex subunit 2 CNDH2_N PF06278.11 KHN70287.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal PcF PF09461.10 KHN70287.1 - 0.15 12.4 1.1 0.34 11.3 0.1 2.1 2 0 0 2 2 2 0 Phytotoxin PcF protein MiAMP1 PF09117.10 KHN70287.1 - 0.3 11.3 1.8 12 6.2 0.2 2.7 2 0 0 2 2 2 0 MiAMP1 PMT PF02366.18 KHN70288.1 - 5.2e-58 196.5 19.1 5.2e-58 196.5 19.1 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KHN70288.1 - 5e-41 140.5 11.2 5e-41 140.5 11.2 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KHN70288.1 - 1.9e-17 63.7 0.1 3.4e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 MIR domain BRCT PF00533.26 KHN70290.1 - 5.1e-23 81.3 0.5 0.00073 19.9 0.0 6.2 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KHN70290.1 - 2.8e-16 59.7 0.5 1.4e-08 35.0 0.0 3.8 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KHN70290.1 - 1.9e-12 47.0 0.0 0.00045 20.0 0.0 4.4 3 1 0 3 3 3 3 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KHN70290.1 - 2.8e-12 46.4 0.3 0.013 15.4 0.0 5.5 6 0 0 6 6 6 3 twin BRCT domain LIG3_BRCT PF16759.5 KHN70290.1 - 0.00084 19.6 0.1 0.024 14.9 0.0 3.2 3 2 0 3 3 3 1 DNA ligase 3 BRCT domain V-ATPase_G PF03179.15 KHN70291.1 - 7e-08 33.0 8.2 8.6e-08 32.7 8.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PIN_8 PF18476.1 KHN70291.1 - 0.0029 17.5 2.0 0.0033 17.3 2.0 1.0 1 0 0 1 1 1 1 PIN like domain Vip3A_N PF12495.8 KHN70291.1 - 0.014 15.3 0.2 0.015 15.2 0.2 1.0 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal OmpH PF03938.14 KHN70291.1 - 0.055 13.8 4.4 0.062 13.6 4.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V-ATPase_G_2 PF16999.5 KHN70291.1 - 0.17 12.3 9.8 0.26 11.7 9.7 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2203 PF09969.9 KHN70291.1 - 0.2 12.4 3.8 0.26 12.0 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATP-synt_B PF00430.18 KHN70291.1 - 0.21 11.7 8.5 0.28 11.3 8.5 1.3 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) KxDL PF10241.9 KHN70291.1 - 0.35 11.2 5.2 4.5 7.6 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF883 PF05957.13 KHN70291.1 - 0.86 10.2 6.0 1.3 9.6 3.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Tugs PF17840.1 KHN70291.1 - 9.5 6.5 8.0 1.2 9.4 0.2 2.9 3 1 1 4 4 4 0 Tethering Ubl4a to BAGS domain ThiF PF00899.21 KHN70292.1 - 1.1e-47 162.4 1.3 1.4e-47 162.1 1.3 1.2 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 KHN70292.1 - 0.012 16.1 0.0 0.037 14.5 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 KHN70292.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain UBA_e1_thiolCys PF10585.9 KHN70292.1 - 0.03 14.3 0.5 5.9 6.7 0.2 2.3 1 1 2 3 3 2 0 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 KHN70292.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KHN70292.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase E2F_CC-MB PF16421.5 KHN70293.1 - 4.4e-19 68.6 0.1 8.8e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 KHN70293.1 - 3.2e-18 65.5 1.3 1.2e-17 63.7 0.1 2.3 3 0 0 3 3 3 1 E2F/DP family winged-helix DNA-binding domain HflK_N PF12221.8 KHN70293.1 - 0.032 14.3 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial membrane protein N terminal ProRS-C_1 PF09180.11 KHN70294.1 - 4.3e-23 81.3 1.3 3.3e-22 78.5 1.4 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KHN70294.1 - 3.1e-19 68.9 0.1 6.2e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KHN70294.1 - 3.8e-19 69.3 0.0 9.5e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Trehalase PF01204.18 KHN70295.1 - 5.2e-135 451.2 0.5 6.6e-135 450.8 0.5 1.1 1 0 0 1 1 1 1 Trehalase Peptidase_M48 PF01435.18 KHN70296.1 - 3.5e-40 137.9 0.0 7e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 KHN70296.1 - 1.5e-35 122.7 14.6 1.5e-35 122.7 14.6 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 KHN70296.1 - 4.6e-05 22.8 4.0 4.6e-05 22.8 4.0 2.5 2 1 1 3 3 3 2 BlaR1 peptidase M56 DUF1772 PF08592.11 KHN70296.1 - 0.054 13.8 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) SprT-like PF10263.9 KHN70296.1 - 0.16 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 SprT-like family ERCC4 PF02732.15 KHN70297.1 - 2e-23 83.3 1.0 3.4e-23 82.6 0.5 1.7 2 0 0 2 2 2 1 ERCC4 domain HHH_2 PF12826.7 KHN70297.1 - 0.00023 21.2 0.1 0.11 12.7 0.0 3.0 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.6 KHN70297.1 - 0.00095 19.7 0.1 0.38 11.4 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH_8 PF14716.6 KHN70297.1 - 0.011 16.1 0.3 0.11 12.9 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_3 PF12836.7 KHN70297.1 - 0.061 13.6 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Arena_ncap_C PF17290.2 KHN70297.1 - 0.39 10.0 2.8 3.2 7.0 0.2 2.9 3 0 0 3 3 3 0 Arenavirus nucleocapsid C-terminal domain WD40 PF00400.32 KHN70299.1 - 7.5e-36 121.5 12.7 8.4e-07 29.6 0.3 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70299.1 - 9.5e-19 67.5 2.4 0.0086 16.4 0.1 6.1 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KHN70299.1 - 0.00053 19.4 0.0 0.38 10.0 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KHN70299.1 - 0.027 13.4 0.0 0.3 10.0 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GDI PF00996.18 KHN70300.1 - 3.2e-90 302.7 0.7 3.8e-90 302.5 0.7 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor RNase_PH PF01138.21 KHN70301.1 - 0.0075 16.8 0.6 0.14 12.7 0.5 2.5 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 ATP_bind_1 PF03029.17 KHN70302.1 - 1.2e-55 188.9 0.3 2.4e-55 188.0 0.3 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KHN70302.1 - 6.7e-05 22.9 0.0 0.00049 20.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 KHN70302.1 - 7.1e-05 22.5 0.0 0.009 15.7 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 KHN70302.1 - 7.1e-05 22.5 0.1 0.00026 20.6 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KHN70302.1 - 0.00014 21.8 0.1 0.18 11.7 0.0 3.1 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KHN70302.1 - 0.00016 21.3 0.0 0.001 18.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KHN70302.1 - 0.00026 21.3 0.0 0.0004 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 KHN70302.1 - 0.0013 18.2 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 KHN70302.1 - 0.0033 16.9 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 KHN70302.1 - 0.0034 17.9 0.0 0.0074 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 KHN70302.1 - 0.0058 16.6 0.1 0.0096 15.9 0.1 1.3 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 KHN70302.1 - 0.0061 16.3 0.5 0.12 12.2 0.0 2.5 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KHN70302.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.15 KHN70302.1 - 0.0074 16.2 0.1 0.031 14.2 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KHN70302.1 - 0.009 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KHN70302.1 - 0.012 15.8 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KHN70302.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 KHN70302.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_16 PF13191.6 KHN70302.1 - 0.028 14.8 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 KHN70302.1 - 0.03 14.1 0.1 7.2 6.4 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 KHN70302.1 - 0.057 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 KHN70302.1 - 0.087 13.0 0.1 2 8.7 0.0 2.4 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KHN70302.1 - 0.099 12.4 0.2 0.31 10.7 0.1 2.0 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KHN70302.1 - 0.1 12.1 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.22 KHN70302.1 - 0.12 12.8 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase T2SSE PF00437.20 KHN70302.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 KHN70302.1 - 0.15 12.1 0.0 0.66 10.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KHN70302.1 - 0.17 12.4 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 KHN70302.1 - 0.2 10.6 0.0 8.2 5.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RIBIOP_C PF04950.12 KHN70303.1 - 3.7e-30 105.4 1.4 5.6e-30 104.8 1.4 1.2 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Pkinase PF00069.25 KHN70304.1 - 1.6e-63 214.6 0.0 7.7e-63 212.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70304.1 - 1.1e-26 93.7 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KHN70304.1 - 0.0073 15.1 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KHN70304.1 - 0.026 13.8 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KHN70304.1 - 0.04 12.9 0.0 0.081 11.9 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Sec23_helical PF04815.15 KHN70305.1 - 1.5e-07 31.1 1.1 8.3e-07 28.8 0.2 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KHN70305.1 - 7.2e-07 29.9 1.2 2.3e-06 28.3 1.2 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KHN70305.1 - 8.8e-06 25.5 0.0 1.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 KHN70305.1 - 0.00022 21.2 9.3 0.00042 20.3 7.4 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger PRA1 PF03208.19 KHN70306.1 - 1.8e-18 66.6 0.3 2.1e-18 66.3 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein PrgI PF12666.7 KHN70306.1 - 0.016 15.9 3.1 0.11 13.2 0.1 2.3 2 0 0 2 2 2 0 PrgI family protein Spc24 PF08286.11 KHN70307.1 - 1.3e-06 28.6 1.2 1.3e-06 28.6 1.2 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 MogR_DNAbind PF12181.8 KHN70307.1 - 0.00025 21.0 4.6 0.00054 19.9 0.2 2.1 1 1 1 2 2 2 1 DNA binding domain of the motility gene repressor (MogR) Tropomyosin_1 PF12718.7 KHN70307.1 - 0.00075 19.7 11.4 0.0011 19.1 11.4 1.2 1 0 0 1 1 1 1 Tropomyosin like AAA_13 PF13166.6 KHN70307.1 - 0.0013 17.5 9.1 0.0014 17.4 9.1 1.0 1 0 0 1 1 1 1 AAA domain CortBP2 PF09727.9 KHN70307.1 - 0.0035 17.3 10.5 0.005 16.8 10.5 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 TelA PF05816.11 KHN70307.1 - 0.006 15.7 8.7 0.0083 15.2 8.7 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) CENP_C_N PF15622.6 KHN70307.1 - 0.024 14.1 4.5 0.032 13.7 4.5 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal Spc7 PF08317.11 KHN70307.1 - 0.027 13.4 11.7 0.035 13.0 11.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 KHN70307.1 - 0.036 13.3 5.4 0.046 13.0 5.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein Transcrip_act PF04949.13 KHN70307.1 - 0.042 13.7 9.8 0.078 12.9 9.7 1.5 1 1 0 1 1 1 0 Transcriptional activator DLP_helical PF18709.1 KHN70307.1 - 0.055 12.7 8.5 0.77 8.9 1.9 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain Taxilin PF09728.9 KHN70307.1 - 0.064 12.4 17.1 0.16 11.2 17.1 1.5 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DivIC PF04977.15 KHN70307.1 - 0.064 13.0 12.2 1.5 8.7 5.0 2.7 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 KHN70307.1 - 0.07 13.2 12.5 1.3 9.1 2.2 2.6 1 1 1 2 2 2 0 bZIP transcription factor KASH_CCD PF14662.6 KHN70307.1 - 0.075 12.8 13.5 0.088 12.6 13.5 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 KHN70307.1 - 0.11 12.7 9.9 1.4 9.1 11.1 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 KHN70307.1 - 0.14 10.1 4.5 0.17 9.8 4.5 1.1 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.12 KHN70307.1 - 0.2 11.7 9.2 1.3 9.1 1.2 2.1 1 1 1 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 KHN70307.1 - 0.21 11.1 4.4 0.24 10.9 4.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cnn_1N PF07989.11 KHN70307.1 - 0.22 11.7 13.2 1.6 8.9 11.9 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 CALCOCO1 PF07888.11 KHN70307.1 - 0.24 10.2 11.5 5.7 5.7 11.3 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HalX PF08663.10 KHN70307.1 - 0.27 11.6 3.2 0.48 10.8 3.2 1.4 1 0 0 1 1 1 0 HalX domain DUF4472 PF14739.6 KHN70307.1 - 0.27 12.0 11.8 0.07 13.9 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 KHN70307.1 - 0.29 10.9 13.6 1.4 8.7 13.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 KHN70307.1 - 0.3 11.1 9.6 0.36 10.9 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 KHN70307.1 - 0.32 11.1 9.6 3.2 7.9 2.8 3.1 2 1 0 2 2 2 0 Basic region leucine zipper DUF4164 PF13747.6 KHN70307.1 - 0.35 11.2 7.9 0.69 10.2 7.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Cep57_MT_bd PF06657.13 KHN70307.1 - 0.43 11.1 7.3 0.37 11.3 1.2 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HisKA_3 PF07730.13 KHN70307.1 - 0.52 10.9 4.3 1.2 9.7 0.3 2.3 2 0 0 2 2 2 0 Histidine kinase TMF_TATA_bd PF12325.8 KHN70307.1 - 0.68 10.2 14.2 0.094 12.9 6.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Macoilin PF09726.9 KHN70307.1 - 0.84 8.1 10.2 1 7.8 10.2 1.0 1 0 0 1 1 1 0 Macoilin family CENP-H PF05837.12 KHN70307.1 - 0.86 10.0 13.0 0.78 10.2 10.2 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 KHN70307.1 - 0.95 9.5 19.7 0.13 12.2 10.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DMPK_coil PF08826.10 KHN70307.1 - 1.1 9.4 8.7 0.23 11.6 1.8 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like YabA PF06156.13 KHN70307.1 - 1.4 9.6 12.2 1 10.0 6.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 KHN70307.1 - 1.5 8.9 13.4 3 7.9 4.2 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 KHN70307.1 - 4.6 5.7 11.1 6.9 5.2 11.1 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A JIP_LZII PF16471.5 KHN70307.1 - 6.4 7.0 13.4 3.9 7.7 6.8 2.5 1 1 0 2 2 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 KHN70307.1 - 6.4 7.5 7.3 4.1 8.1 2.0 2.6 1 1 1 2 2 2 0 SlyX APG6_N PF17675.1 KHN70307.1 - 7.2 7.1 15.4 41 4.7 15.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region BST2 PF16716.5 KHN70307.1 - 9.1 6.9 10.4 3.4 8.3 5.3 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 tRNA-synt_2c PF01411.19 KHN70308.1 - 3.9e-161 537.3 0.0 6.7e-161 536.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KHN70308.1 - 4.7e-13 49.0 0.5 2.4e-12 46.8 0.5 2.3 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Kri1 PF05178.12 KHN70308.1 - 3.4 8.3 9.7 0.85 10.2 1.4 2.8 3 0 0 3 3 3 0 KRI1-like family TFIID_20kDa PF03847.13 KHN70309.1 - 6.1e-09 36.3 0.8 7.9e-09 35.9 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KHN70309.1 - 2.1e-06 27.8 0.0 2.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF4 PF05236.14 KHN70309.1 - 1.5e-05 24.9 0.3 1.5e-05 24.9 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Histone PF00125.24 KHN70309.1 - 0.00025 21.4 0.1 0.00032 21.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KHN70309.1 - 0.00036 20.8 0.1 0.00049 20.4 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CENP-T_C PF15511.6 KHN70309.1 - 0.00055 20.0 0.1 0.00063 19.8 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KHN70309.1 - 0.0088 16.0 0.4 0.014 15.4 0.2 1.5 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit FANCI_S1-cap PF14674.6 KHN70309.1 - 0.026 14.6 0.8 0.47 10.6 0.1 2.1 1 1 1 2 2 2 0 FANCI solenoid 1 cap FANCI_S3 PF14677.6 KHN70309.1 - 0.035 13.8 0.3 0.045 13.5 0.3 1.3 1 0 0 1 1 1 0 FANCI solenoid 3 CBFD_NFYB_HMF PF00808.23 KHN70309.1 - 0.045 14.1 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.11 KHN70309.1 - 0.05 13.7 0.4 0.24 11.5 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1931) DEAD PF00270.29 KHN70311.1 - 3.2e-30 105.2 1.3 3.2e-30 105.2 1.3 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN70311.1 - 5.5e-28 97.5 0.3 4.3e-27 94.7 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN70311.1 - 5.9e-06 26.4 0.9 1.1e-05 25.5 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KHN70311.1 - 0.0045 16.3 0.4 0.013 14.8 0.1 1.9 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.6 KHN70311.1 - 0.032 14.0 1.4 0.052 13.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KHN70311.1 - 0.065 13.6 0.5 0.29 11.5 0.2 2.3 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 KHN70311.1 - 0.23 11.0 1.9 1.3 8.5 0.5 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain WD40 PF00400.32 KHN70312.1 - 4.7e-12 46.2 0.0 0.00019 22.1 0.0 4.9 4 1 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KHN70312.1 - 0.00041 20.4 0.1 2.8 8.0 0.0 3.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Imm7 PF15585.6 KHN70312.1 - 0.12 12.6 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 7 Per1 PF04080.13 KHN70313.1 - 6.5e-44 150.6 11.5 7e-44 150.5 11.5 1.0 1 0 0 1 1 1 1 Per1-like family Aa_trans PF01490.18 KHN70314.1 - 1.6e-58 198.4 43.0 1.8e-58 198.2 43.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2238 PF09997.9 KHN70314.1 - 0.23 11.2 8.6 0.15 11.8 2.6 2.8 1 1 2 3 3 3 0 Predicted membrane protein (DUF2238) DASH_Dad4 PF08650.10 KHN70315.1 - 0.074 13.0 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 DEAD PF00270.29 KHN70316.1 - 1.8e-40 138.6 0.1 3.8e-40 137.5 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KHN70316.1 - 3.2e-23 82.2 0.1 3.4e-22 78.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN70316.1 - 1.8e-06 28.0 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 KHN70316.1 - 4.7e-05 23.6 0.1 0.0022 18.2 0.0 2.5 3 0 0 3 3 3 1 Helicase C-terminal domain AAA_30 PF13604.6 KHN70316.1 - 0.0013 18.5 0.1 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 KHN70316.1 - 0.0098 15.2 1.0 0.019 14.3 0.1 2.0 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 KHN70316.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Glycos_transf_1 PF00534.20 KHN70317.1 - 1.1e-24 86.9 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KHN70317.1 - 2.7e-24 86.0 0.4 4.9e-24 85.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 PIGA PF08288.12 KHN70317.1 - 3.8e-23 81.9 0.7 8.3e-23 80.8 0.3 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_4 PF13692.6 KHN70317.1 - 1.5e-22 80.5 0.1 2.7e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KHN70317.1 - 8.1e-08 32.9 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KHN70317.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KHN70317.1 - 0.15 12.5 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 EF-hand_7 PF13499.6 KHN70318.1 - 4.3e-08 33.5 0.2 4.5e-06 27.0 0.0 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KHN70318.1 - 5.1e-06 26.2 0.1 0.0001 22.1 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KHN70318.1 - 0.0013 18.1 0.0 2.2 8.0 0.1 2.9 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 KHN70318.1 - 0.0026 17.6 0.0 1 9.4 0.0 3.4 2 1 1 3 3 3 1 EF-hand domain Lip_prot_lig_C PF10437.9 KHN70318.1 - 0.008 16.1 0.1 0.02 14.9 0.1 1.7 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus EF-hand_9 PF14658.6 KHN70318.1 - 0.02 15.2 0.0 4.2 7.8 0.0 2.3 2 1 1 3 3 3 0 EF-hand domain Myosin_tail_1 PF01576.19 KHN70318.1 - 0.12 10.2 0.1 0.14 10.0 0.1 1.1 1 0 0 1 1 1 0 Myosin tail KH_6 PF15985.5 KHN70320.1 - 6.9e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 KH domain S1 PF00575.23 KHN70320.1 - 0.012 15.9 0.5 0.099 13.0 0.0 2.3 2 0 0 2 2 2 0 S1 RNA binding domain Ribosomal_S3_C PF00189.20 KHN70321.1 - 2.6e-20 72.7 6.5 5e-20 71.8 6.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KHN70321.1 - 0.0055 16.5 0.3 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 KH domain RIO1 PF01163.22 KHN70322.1 - 2.4e-31 108.8 0.3 3.6e-31 108.2 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KHN70322.1 - 2.2e-13 50.2 0.0 4.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal Pkinase PF00069.25 KHN70322.1 - 7.8e-05 22.2 0.1 0.00015 21.3 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KHN70322.1 - 0.0019 18.2 0.4 0.0048 16.9 0.3 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KHN70322.1 - 0.042 13.2 0.1 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HU-DNA_bdg PF14848.6 KHN70322.1 - 0.048 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA-binding domain GLE1 PF07817.13 KHN70323.1 - 0.0014 17.9 0.2 1.8 7.7 0.0 2.7 3 0 0 3 3 3 2 GLE1-like protein Ribosomal_S28e PF01200.18 KHN70324.1 - 7e-20 70.8 0.7 7.8e-20 70.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e CARD PF00619.21 KHN70325.1 - 0.041 13.9 0.3 0.12 12.4 0.3 1.6 2 0 0 2 2 2 0 Caspase recruitment domain zf-CRD PF17979.1 KHN70325.1 - 0.069 13.3 0.4 0.1 12.7 0.4 1.4 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Utp11 PF03998.13 KHN70326.1 - 3.7e-09 36.9 9.8 6.1e-09 36.2 9.8 1.3 1 1 0 1 1 1 1 Utp11 protein DUF4140 PF13600.6 KHN70326.1 - 0.015 15.7 3.2 1 9.9 1.2 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.20 KHN70326.1 - 0.13 12.3 8.5 0.6 10.1 0.0 3.1 3 0 0 3 3 3 0 Prefoldin subunit STAT_alpha PF01017.20 KHN70326.1 - 0.2 11.6 3.0 0.49 10.3 0.1 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF1192 PF06698.11 KHN70326.1 - 1.8 8.7 4.6 2.6 8.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) zf-Nse PF11789.8 KHN70327.1 - 6.7e-08 32.2 0.5 1.6e-07 31.0 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit MOZ_SAS PF01853.18 KHN70328.1 - 4.8e-45 153.4 0.2 6.9e-45 152.9 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 KHN70328.1 - 0.0071 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-MYST PF17772.1 KHN70328.1 - 0.016 14.8 3.0 0.054 13.1 0.8 2.4 2 0 0 2 2 2 0 MYST family zinc finger domain Acetyltransf_10 PF13673.7 KHN70328.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_19 PF00182.19 KHN70329.1 - 3.3e-17 63.2 0.8 2e-14 54.0 0.6 2.4 1 1 1 2 2 2 2 Chitinase class I GILT PF03227.16 KHN70329.1 - 0.053 13.8 2.9 0.063 13.5 1.3 1.9 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Metallothi_Euk2 PF12809.7 KHN70329.1 - 2.8 8.3 11.2 0.23 11.7 5.5 2.2 2 0 0 2 2 2 0 Eukaryotic metallothionein DNA_pol3_delta2 PF13177.6 KHN70330.1 - 5e-19 68.7 0.1 5.2e-13 49.1 0.2 2.6 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KHN70330.1 - 2.7e-15 56.9 0.1 6.4e-15 55.7 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KHN70330.1 - 3.1e-13 49.9 0.1 1.8e-12 47.5 0.0 2.2 2 1 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 KHN70330.1 - 3e-08 34.0 2.4 0.00014 22.1 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_assoc_2 PF16193.5 KHN70330.1 - 3.6e-08 33.6 0.1 2.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_gamma3 PF12169.8 KHN70330.1 - 6.2e-07 29.4 0.0 8.3e-05 22.5 0.0 2.5 1 1 1 2 2 2 1 DNA polymerase III subunits gamma and tau domain III RuvB_N PF05496.12 KHN70330.1 - 9.9e-07 28.6 0.0 3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KHN70330.1 - 1.8e-06 27.8 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KHN70330.1 - 2e-06 27.9 0.0 3.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KHN70330.1 - 5.3e-06 26.9 0.0 0.0012 19.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KHN70330.1 - 8e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KHN70330.1 - 3.2e-05 23.4 0.0 0.00016 21.2 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 KHN70330.1 - 5.2e-05 23.2 0.0 0.00014 21.8 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 KHN70330.1 - 6.6e-05 23.1 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KHN70330.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KHN70330.1 - 0.00014 21.7 0.1 0.00088 19.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KHN70330.1 - 0.00025 21.6 0.0 0.00051 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KHN70330.1 - 0.00038 20.4 1.2 0.024 14.5 0.1 2.6 1 1 2 3 3 3 1 NTPase TniB PF05621.11 KHN70330.1 - 0.0005 19.5 0.5 0.33 10.3 0.0 2.7 2 1 0 3 3 2 1 Bacterial TniB protein KTI12 PF08433.10 KHN70330.1 - 0.00057 19.4 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 KHN70330.1 - 0.00064 19.7 0.2 0.004 17.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KHN70330.1 - 0.00078 19.8 0.2 0.0025 18.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KHN70330.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KHN70330.1 - 0.0019 18.6 0.0 0.0045 17.4 0.0 1.8 1 1 0 1 1 1 1 RNA helicase DNA_pol3_delta PF06144.13 KHN70330.1 - 0.0031 17.3 0.4 0.0071 16.1 0.4 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_28 PF13521.6 KHN70330.1 - 0.0037 17.5 0.0 0.0061 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KHN70330.1 - 0.0057 17.2 0.0 0.019 15.5 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_11 PF13086.6 KHN70330.1 - 0.006 16.4 1.3 0.078 12.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 KHN70330.1 - 0.006 16.1 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ResIII PF04851.15 KHN70330.1 - 0.0076 16.3 0.1 0.56 10.2 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN70330.1 - 0.0093 15.8 0.6 0.63 9.8 0.1 2.5 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.6 KHN70330.1 - 0.014 15.5 1.3 0.049 13.8 1.3 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KHN70330.1 - 0.02 14.6 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 KHN70330.1 - 0.023 14.1 0.0 0.065 12.6 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 KHN70330.1 - 0.025 14.5 0.0 0.67 9.9 0.0 2.3 1 1 1 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KHN70330.1 - 0.046 13.4 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 KHN70330.1 - 0.062 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) T2SSE PF00437.20 KHN70330.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 KHN70330.1 - 0.075 12.3 0.5 1.6 7.8 0.5 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 KHN70330.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 KHN70330.1 - 0.13 12.7 0.2 0.31 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KHN70330.1 - 0.13 11.9 0.3 0.32 10.6 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KHN70331.1 - 0.0014 19.0 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KHN70331.1 - 0.0087 16.3 0.2 0.02 15.1 0.2 1.5 1 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KHN70331.1 - 0.0092 16.5 0.1 0.012 16.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KHN70331.1 - 0.012 16.2 0.1 0.012 16.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KHN70331.1 - 0.012 15.2 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KHN70331.1 - 0.012 15.8 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KHN70331.1 - 0.016 15.3 0.1 0.033 14.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KHN70331.1 - 0.019 15.4 0.0 0.024 15.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KHN70331.1 - 0.025 14.6 0.1 0.035 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KHN70331.1 - 0.032 13.9 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KHN70331.1 - 0.034 13.2 0.1 0.041 12.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 KHN70331.1 - 0.063 12.9 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ribosomal_S8 PF00410.19 KHN70332.1 - 4e-17 62.4 0.0 7.6e-17 61.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 ANF_receptor PF01094.28 KHN70332.1 - 0.058 12.5 0.0 0.13 11.4 0.0 1.5 1 1 1 2 2 2 0 Receptor family ligand binding region MCM PF00493.23 KHN70333.1 - 2.8e-94 314.4 0.2 4.6e-94 313.7 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN70333.1 - 1.2e-27 96.2 2.4 2.2e-27 95.4 2.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KHN70333.1 - 5.2e-18 65.3 0.4 1e-17 64.3 0.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KHN70333.1 - 3.1e-07 30.0 0.1 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 KHN70333.1 - 1.4e-06 28.8 0.4 3.3e-06 27.6 0.4 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KHN70333.1 - 1.4e-06 28.3 0.0 5.3e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KHN70333.1 - 0.00067 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-UDP PF14569.6 KHN70333.1 - 0.0094 16.0 0.3 0.022 14.9 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger Sigma54_activat PF00158.26 KHN70333.1 - 0.0099 15.6 0.1 0.068 12.9 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 KHN70333.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DZF PF07528.14 KHN70333.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 DZF domain AWS PF17907.1 KHN70333.1 - 0.21 11.6 1.4 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 AWS domain HAS-barrel PF09378.10 KHN70334.1 - 0.0012 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 HAS barrel domain EFP_N PF08207.12 KHN70334.1 - 0.045 13.8 0.4 0.082 13.0 0.4 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Glutaredoxin PF00462.24 KHN70335.1 - 1.3e-11 44.5 0.0 2.4e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KHN70335.1 - 0.055 13.9 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain NMD3 PF04981.13 KHN70336.1 - 4.4e-62 209.7 7.9 4.4e-62 209.7 7.9 2.0 3 0 0 3 3 3 1 NMD3 family Yippee-Mis18 PF03226.14 KHN70336.1 - 0.018 15.2 1.5 1.4 9.2 0.2 2.7 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TIP49 PF06068.13 KHN70337.1 - 1.2e-147 491.7 3.5 1.5e-147 491.4 3.5 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KHN70337.1 - 1.1e-16 60.7 0.1 2.6e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KHN70337.1 - 7.7e-10 39.3 0.4 3.8e-05 24.1 0.1 2.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KHN70337.1 - 3.2e-07 30.2 0.1 7.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KHN70337.1 - 1.1e-05 25.7 1.2 0.0048 17.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KHN70337.1 - 0.00026 21.4 0.0 0.0047 17.3 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KHN70337.1 - 0.00079 19.4 0.0 0.24 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KHN70337.1 - 0.0043 17.1 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KHN70337.1 - 0.0067 16.2 0.1 3.4 7.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 KHN70337.1 - 0.013 15.3 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Rad17 PF03215.15 KHN70337.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KHN70337.1 - 0.027 13.8 0.2 0.81 9.0 0.1 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KHN70337.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KHN70337.1 - 0.03 14.8 0.0 0.05 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KHN70337.1 - 0.036 14.4 2.4 1.2 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KHN70337.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.27 KHN70338.1 - 1.4e-10 41.2 2.5 8.4e-10 38.7 0.4 2.2 2 1 0 2 2 2 1 RhoGAP domain Ufd2P_core PF10408.9 KHN70338.1 - 0.0074 15.0 1.8 0.0078 14.9 1.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core zf-CCCH PF00642.24 KHN70339.1 - 0.0002 21.2 3.2 0.0002 21.2 3.2 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KHN70339.1 - 0.016 15.9 23.8 0.28 11.9 0.1 3.5 3 1 0 3 3 3 0 Torus domain PhoLip_ATPase_C PF16212.5 KHN70340.1 - 2.3e-36 125.8 26.1 2.3e-36 125.8 26.1 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KHN70340.1 - 1.6e-11 44.9 0.6 6.6e-07 29.8 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KHN70340.1 - 4.4e-08 32.7 4.4 1.4e-07 31.1 4.4 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KHN70340.1 - 5.7e-08 32.7 0.0 5.5e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KHN70340.1 - 2.4e-05 24.0 11.4 4.7e-05 23.0 0.0 3.5 3 1 0 3 3 3 2 E1-E2 ATPase Ras PF00071.22 KHN70341.1 - 8.7e-50 168.5 0.9 1e-49 168.3 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KHN70341.1 - 6.5e-34 116.7 1.1 1.5e-33 115.5 0.2 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KHN70341.1 - 3.6e-19 68.9 0.2 4.1e-19 68.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KHN70341.1 - 1.5e-09 37.7 0.3 8.6e-08 31.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KHN70341.1 - 2.1e-09 37.1 0.3 2.6e-09 36.8 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KHN70341.1 - 3.9e-07 30.1 0.0 9e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KHN70341.1 - 2.1e-06 27.8 0.1 4.1e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KHN70341.1 - 1.9e-05 24.2 0.1 2.4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KHN70341.1 - 0.13 12.5 0.1 0.39 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 KHN70341.1 - 0.59 9.2 5.3 4.3 6.4 0.4 2.9 1 1 2 3 3 3 0 G-protein alpha subunit WD40 PF00400.32 KHN70342.1 - 0.00021 22.0 0.4 0.053 14.4 0.0 4.0 4 1 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KHN70342.1 - 0.032 13.0 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Cytochrom_D1 PF02239.16 KHN70342.1 - 0.033 12.7 0.1 0.073 11.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KHN70342.1 - 0.063 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_6 PF14835.6 KHN70342.1 - 0.11 12.4 0.6 0.25 11.2 0.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RRM_1 PF00076.22 KHN70343.1 - 1.5e-08 34.3 0.4 0.0026 17.6 0.0 3.1 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KHN70344.1 - 1.1e-07 32.4 8.1 0.39 11.7 0.0 5.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70344.1 - 0.00097 19.4 0.3 0.066 13.5 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 KHN70344.1 - 0.07 12.5 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region HEAT_2 PF13646.6 KHN70345.1 - 1.4e-14 54.2 0.5 0.01 16.2 0.0 5.3 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KHN70345.1 - 9.4e-14 50.3 1.5 1.2 9.6 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat Cohesin_HEAT PF12765.7 KHN70345.1 - 0.0071 16.6 2.2 1.6 9.1 0.2 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion DNA_alkylation PF08713.11 KHN70345.1 - 0.0097 15.6 0.3 0.077 12.7 0.0 2.4 1 1 1 2 2 2 1 DNA alkylation repair enzyme GCR1_C PF12550.8 KHN70345.1 - 0.01 16.1 0.6 0.066 13.5 0.1 2.6 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Myb_DNA-bind_6 PF13921.6 KHN70345.1 - 0.1 12.8 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 KHN70346.1 - 7.5e-15 55.4 0.1 1.3e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KHN70346.1 - 1.9e-12 47.7 0.7 6.1e-12 46.1 0.7 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KHN70346.1 - 7.6e-10 38.9 0.0 1.7e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KHN70346.1 - 7.4e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KHN70346.1 - 5.8e-06 27.0 0.4 5e-05 24.0 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KHN70346.1 - 0.0023 17.3 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 KHN70346.1 - 0.058 12.8 0.2 0.35 10.2 0.2 2.0 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 KHN70346.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribo_biogen_C PF04034.13 KHN70348.1 - 4.5e-52 175.1 0.0 5.7e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KHN70348.1 - 5.7e-10 38.8 1.5 5.7e-10 38.8 1.5 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Plk4_PB2 PF18409.1 KHN70350.1 - 0.039 14.6 0.7 0.079 13.7 0.7 1.5 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 DUF3567 PF12091.8 KHN70354.1 - 0.055 13.6 0.0 0.28 11.3 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) HMG_box_5 PF14887.6 KHN70354.1 - 0.34 10.9 4.2 0.36 10.8 1.2 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box 5 LRR_4 PF12799.7 KHN70355.1 - 2.7e-10 40.3 4.1 1.5e-05 25.2 0.2 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KHN70355.1 - 8.9e-07 28.6 7.9 0.068 12.9 0.4 3.3 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 KHN70355.1 - 3.1e-05 23.7 9.7 3.2 8.0 0.1 5.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 KHN70355.1 - 0.015 14.8 1.6 0.098 12.2 1.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 KHN70355.1 - 0.041 14.4 9.3 7.7 7.5 0.2 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat Sortilin-Vps10 PF15902.5 KHN70355.1 - 0.057 12.2 0.1 0.087 11.6 0.0 1.4 1 1 0 1 1 1 0 Sortilin, neurotensin receptor 3, LRR_4 PF12799.7 KHN70356.1 - 0.012 16.0 0.1 4.4 7.8 0.1 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DNA_III_psi PF03603.13 KHN70356.1 - 0.038 14.2 0.0 0.06 13.6 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III psi subunit LRR_1 PF00560.33 KHN70356.1 - 0.047 14.3 0.0 12 7.0 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KHN70356.1 - 0.14 12.2 0.1 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeat DUF4231 PF14015.6 KHN70357.1 - 0.0029 18.0 0.7 0.0029 18.0 0.7 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF4231) AzlD PF05437.12 KHN70357.1 - 0.007 16.5 0.1 0.007 16.5 0.1 2.7 2 2 1 3 3 3 1 Branched-chain amino acid transport protein (AzlD) DUF2615 PF11027.8 KHN70357.1 - 0.13 12.4 1.0 2.6 8.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF373 PF04123.13 KHN70357.1 - 2.2 7.6 14.8 1.4 8.3 2.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF373) UBX PF00789.20 KHN70358.1 - 0.00025 21.2 0.0 0.00059 20.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain Pox_P4A PF03395.14 KHN70358.1 - 0.00051 17.8 1.7 0.00065 17.4 1.7 1.0 1 0 0 1 1 1 1 Poxvirus P4A protein Ndc80_HEC PF03801.13 KHN70358.1 - 0.05 13.2 2.5 4.9 6.8 0.0 2.2 1 1 1 2 2 2 0 HEC/Ndc80p family Pex14_N PF04695.13 KHN70358.1 - 0.13 12.9 3.0 0.16 12.6 3.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRP-L28 PF09812.9 KHN70358.1 - 0.18 11.9 5.3 0.24 11.5 5.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Glycolytic PF00274.19 KHN70359.1 - 6.5e-106 354.0 0.0 8e-106 353.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF866 PF05907.13 KHN70360.1 - 2.4e-10 40.5 3.8 3e-10 40.2 3.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HSP33 PF01430.19 KHN70360.1 - 0.018 14.4 1.8 0.026 14.0 1.8 1.2 1 0 0 1 1 1 0 Hsp33 protein Dynein_light PF01221.18 KHN70361.1 - 9.7e-14 51.5 0.1 1.4e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 ORC3_N PF07034.11 KHN70361.1 - 0.09 11.9 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus ICAM_N PF03921.14 KHN70362.1 - 0.16 11.6 1.1 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain zf-C2H2_jaz PF12171.8 KHN70363.1 - 1.8e-05 24.9 2.3 3.6e-05 23.9 2.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding FRP PF18032.1 KHN70363.1 - 0.00084 19.9 0.1 0.0014 19.2 0.1 1.4 1 0 0 1 1 1 1 Photoprotection regulator fluorescence recovery protein zf-C2H2_2 PF12756.7 KHN70363.1 - 0.0018 18.5 3.0 0.003 17.9 2.9 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KHN70363.1 - 0.0064 16.9 1.2 0.014 15.8 1.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type RE_CfrBI PF09516.10 KHN70363.1 - 0.02 14.3 0.3 0.026 13.9 0.3 1.2 1 0 0 1 1 1 0 CfrBI restriction endonuclease Z1 PF10593.9 KHN70363.1 - 0.052 13.0 0.8 0.06 12.8 0.8 1.1 1 0 0 1 1 1 0 Z1 domain DUF445 PF04286.12 KHN70363.1 - 0.054 13.3 0.6 0.091 12.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) zf-C2H2_4 PF13894.6 KHN70363.1 - 0.057 14.3 0.2 0.17 12.8 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-LYAR PF08790.11 KHN70363.1 - 0.089 12.7 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DUF2207 PF09972.9 KHN70364.1 - 0.018 13.8 0.5 0.02 13.7 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2205 PF10224.9 KHN70364.1 - 0.044 13.8 1.4 0.1 12.6 0.4 1.8 1 1 1 2 2 2 0 Short coiled-coil protein Spore_YhaL PF14147.6 KHN70364.1 - 0.64 9.7 6.9 4.1 7.2 2.3 2.6 2 0 0 2 2 2 0 Sporulation protein YhaL Ribosomal_L2_C PF03947.18 KHN70365.1 - 1.9e-34 118.6 2.1 3e-34 118.0 2.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KHN70365.1 - 2.8e-07 30.4 0.1 1.5e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Prot_inhib_II PF02428.15 KHN70366.1 - 0.048 14.1 0.9 0.085 13.3 0.9 1.3 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Mpp10 PF04006.12 KHN70367.1 - 1.8e-13 49.9 2.8 1.8e-13 49.9 2.8 1.4 1 1 0 2 2 2 1 Mpp10 protein NIF PF03031.18 KHN70368.1 - 1.2e-16 60.9 0.2 1.4e-16 60.6 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 KHN70368.1 - 0.0035 17.4 0.0 0.042 14.0 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KHN70368.1 - 0.12 12.3 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Acid Phosphatase SNF2_N PF00176.23 KHN70369.1 - 2.7e-60 203.9 0.4 1.1e-59 201.9 0.4 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KHN70369.1 - 1.6e-19 70.3 0.0 1e-18 67.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 KHN70369.1 - 2.4e-15 56.2 4.3 2.9e-10 39.9 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KHN70369.1 - 1.1e-12 48.3 0.2 3.8e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KHN70369.1 - 1.3e-05 25.1 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KHN70369.1 - 3.9e-05 23.0 0.0 9.4e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF4250 PF14056.6 KHN70369.1 - 0.17 11.9 2.0 4.1 7.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) AT_hook PF02178.19 KHN70369.1 - 0.17 11.8 5.2 0.47 10.5 5.2 1.8 1 0 0 1 1 1 0 AT hook motif Brix PF04427.18 KHN70370.1 - 4.9e-11 43.1 0.0 6.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain DnaJ PF00226.31 KHN70371.1 - 0.0025 17.9 0.0 0.0072 16.4 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-bind_5 PF13873.6 KHN70371.1 - 0.0053 16.8 3.1 0.021 14.9 0.8 2.4 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain CobW_C PF07683.14 KHN70371.1 - 0.072 13.0 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Rcd1 PF04078.13 KHN70372.1 - 2e-68 230.5 0.4 2.3e-68 230.3 0.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SIX1_SD PF16878.5 KHN70372.1 - 0.019 15.5 0.4 0.044 14.3 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator, SIX1, N-terminal SD domain AD PF09793.9 KHN70372.1 - 0.05 13.7 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain DMAP1_like PF17024.5 KHN70373.1 - 3.6e-42 143.0 3.5 4.3e-42 142.8 3.5 1.0 1 0 0 1 1 1 1 Putative DMAP1-like DUF1768 PF08719.11 KHN70373.1 - 0.022 15.0 0.1 0.025 14.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1768) BLYB PF05289.11 KHN70373.1 - 0.043 14.0 0.8 0.061 13.5 0.8 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Choline_transpo PF04515.12 KHN70374.1 - 3.6e-15 56.0 39.5 2.4e-14 53.3 39.3 2.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter Proton_antipo_N PF00662.20 KHN70374.1 - 0.062 13.4 0.8 0.062 13.4 0.8 3.5 3 2 2 5 5 5 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF3450 PF11932.8 KHN70375.1 - 0.00012 21.4 10.3 0.00012 21.4 10.3 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF3450) DUF5638 PF18688.1 KHN70375.1 - 0.29 11.5 15.8 0.4 11.0 2.9 3.7 3 0 0 3 3 3 0 Family of unknown function (DUF5638) Hist_deacetyl PF00850.19 KHN70375.1 - 0.66 9.4 2.8 0.45 9.9 0.8 1.8 2 0 0 2 2 2 0 Histone deacetylase domain PspB PF06667.12 KHN70375.1 - 2.7 8.1 9.0 29 4.8 0.9 4.2 3 0 0 3 3 3 0 Phage shock protein B BAR_2 PF10455.9 KHN70376.1 - 6.6e-05 22.2 11.8 0.00013 21.2 11.8 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking HMD PF03201.16 KHN70376.1 - 0.093 13.0 1.1 2.1 8.6 0.1 2.4 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF4168 PF13767.6 KHN70376.1 - 0.5 11.6 7.6 11 7.3 6.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Rota_NSP4 PF01452.16 KHN70376.1 - 0.63 9.7 7.9 0.14 11.9 4.0 1.9 2 1 0 2 2 2 0 Rotavirus non structural protein MADF_DNA_bdg PF10545.9 KHN70376.1 - 1.3 9.4 5.7 1.6 9.1 2.8 2.5 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Spore_Cse60 PF10957.8 KHN70376.1 - 5.2 7.2 8.7 1.9 8.6 1.1 3.1 3 0 0 3 3 3 0 Sporulation protein Cse60 LMBR1 PF04791.16 KHN70376.1 - 5.5 5.8 7.8 5.1 5.9 7.0 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein zf-CCCH PF00642.24 KHN70377.1 - 1.8e-10 40.5 38.8 2.5e-05 24.1 0.4 5.0 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KHN70377.1 - 1.7e-08 35.1 28.1 0.0012 19.5 4.6 4.1 1 1 3 4 4 4 4 Torus domain zf_CCCH_4 PF18345.1 KHN70377.1 - 1.4e-07 31.4 44.8 2e-05 24.5 2.9 5.9 5 1 0 5 5 5 3 Zinc finger domain zf-CCCH_4 PF18044.1 KHN70377.1 - 8.4e-06 25.5 0.5 8.4e-06 25.5 0.5 4.8 5 0 0 5 5 5 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KHN70377.1 - 5.2e-05 23.4 27.8 0.057 13.6 1.1 3.9 1 1 1 3 3 3 2 Zinc-finger containing family AWS PF17907.1 KHN70377.1 - 0.066 13.2 0.9 0.066 13.2 0.9 4.6 5 0 0 5 5 5 0 AWS domain zf-C3H1 PF10650.9 KHN70377.1 - 0.36 10.6 19.7 0.78 9.5 0.6 5.4 5 0 0 5 5 5 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 KHN70377.1 - 0.47 11.0 45.0 0.48 11.0 3.4 5.8 5 1 0 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-tcix PF14952.6 KHN70377.1 - 7.5 6.3 17.0 0.98 9.1 2.0 4.0 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding Sporozoite_P67 PF05642.11 KHN70378.1 - 0.0035 15.5 2.0 0.005 15.0 2.0 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen BHD_1 PF10403.9 KHN70379.1 - 1e-13 50.9 0.1 3.3e-13 49.2 0.1 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 KHN70379.1 - 0.0024 18.2 0.0 0.0059 17.0 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 DUF1877 PF08974.10 KHN70379.1 - 0.01 15.9 0.2 3.2 7.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) Actin PF00022.19 KHN70380.1 - 6.5e-145 482.8 0.0 3.2e-144 480.5 0.0 1.8 1 1 0 1 1 1 1 Actin Forkhead PF00250.18 KHN70381.1 - 3.8e-31 107.2 0.3 8.1e-31 106.1 0.3 1.6 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 KHN70381.1 - 0.13 12.7 0.1 0.66 10.4 0.1 2.1 1 1 1 2 2 2 0 linker histone H1 and H5 family EMG1 PF03587.14 KHN70382.1 - 2.3e-27 95.9 0.3 2.8e-27 95.7 0.3 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase XhlA PF10779.9 KHN70383.1 - 0.13 12.4 3.6 0.2 11.9 2.6 1.8 1 1 1 2 2 2 0 Haemolysin XhlA DUF4709 PF15821.5 KHN70383.1 - 0.14 12.4 3.7 0.11 12.8 1.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) CHASE9 PF17153.4 KHN70383.1 - 0.44 10.7 3.4 1.3 9.2 3.4 1.8 1 1 0 1 1 1 0 Periplasmic sensor domain, extracellular Snf7 PF03357.21 KHN70383.1 - 3.3 7.3 8.0 1.6 8.3 1.4 2.1 1 1 1 2 2 2 0 Snf7 Med6 PF04934.14 KHN70384.1 - 7.2e-33 113.2 3.8 9.2e-33 112.9 3.8 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component NifU_N PF01592.16 KHN70385.1 - 2.7e-52 176.3 0.0 3e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain YmzC PF14157.6 KHN70386.1 - 0.022 14.8 0.0 0.082 13.0 0.0 2.0 1 0 0 1 1 1 0 YmzC-like protein RB_A PF01858.17 KHN70386.1 - 0.025 14.4 0.7 0.041 13.7 0.7 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain GRASP55_65 PF04495.14 KHN70388.1 - 5.5e-23 81.8 0.4 4.6e-19 69.1 0.1 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KHN70388.1 - 0.00027 20.7 0.0 0.00063 19.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KHN70388.1 - 0.0028 17.9 0.0 0.027 14.8 0.0 2.5 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 KHN70388.1 - 0.097 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain RRM_1 PF00076.22 KHN70389.1 - 2e-11 43.5 0.0 2e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KHN70389.1 - 0.0013 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif LSM PF01423.22 KHN70390.1 - 1.1e-14 53.8 0.2 1.9e-14 53.1 0.2 1.4 1 0 0 1 1 1 1 LSM domain CAF1C_H4-bd PF12265.8 KHN70392.1 - 0.086 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Cnn_1N PF07989.11 KHN70393.1 - 1.6e-05 25.0 8.1 1.6e-05 25.0 8.1 8.5 4 3 3 8 8 8 1 Centrosomin N-terminal motif 1 GAS PF13851.6 KHN70393.1 - 0.00015 21.2 19.8 0.00015 21.2 19.8 5.8 3 1 3 6 6 6 2 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.11 KHN70393.1 - 0.0012 18.6 1.0 0.0012 18.6 1.0 5.3 6 0 0 6 6 6 1 Shugoshin N-terminal coiled-coil region DUF2353 PF09789.9 KHN70393.1 - 0.0041 16.5 13.4 0.0041 16.5 13.4 4.9 1 1 2 5 5 4 1 Uncharacterized coiled-coil protein (DUF2353) PI3K_P85_iSH2 PF16454.5 KHN70393.1 - 0.0056 16.3 6.4 0.0056 16.3 6.4 6.7 2 1 2 6 6 6 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ERM PF00769.19 KHN70393.1 - 0.013 15.3 13.7 0.013 15.3 13.7 5.3 2 1 2 4 4 3 0 Ezrin/radixin/moesin family ZapB PF06005.12 KHN70393.1 - 0.73 10.3 68.1 0.64 10.5 1.6 8.1 5 1 1 6 6 5 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 KHN70393.1 - 2 8.5 68.4 3.7 7.6 5.9 7.4 4 2 1 6 6 6 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 KHN70393.1 - 2.6 8.3 6.1 54 4.1 0.1 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) MbeD_MobD PF04899.12 KHN70393.1 - 3 8.0 8.1 1.3 9.1 0.1 4.3 3 2 3 6 6 6 0 MbeD/MobD like DUF4472 PF14739.6 KHN70393.1 - 5.6 7.7 59.0 0.52 11.1 4.5 6.1 2 1 2 5 5 5 0 Domain of unknown function (DUF4472) DnaJ PF00226.31 KHN70394.1 - 4.6e-13 49.1 0.3 4.6e-13 49.1 0.3 2.4 2 1 1 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.8 KHN70394.1 - 7.6e-06 26.1 4.9 2.6e-05 24.4 4.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KHN70394.1 - 0.0016 19.1 7.5 0.023 15.5 2.7 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 KHN70394.1 - 0.0054 17.1 7.2 0.018 15.4 7.2 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KHN70394.1 - 0.25 11.7 7.4 1 9.7 3.2 2.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KHN70394.1 - 4.5 7.9 10.0 21 5.8 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type SPO22 PF08631.10 KHN70396.1 - 0.16 11.4 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like RNA_pol_A_bac PF01000.26 KHN70397.1 - 5.3e-20 71.9 0.1 2e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KHN70397.1 - 2.9e-14 52.2 0.0 4.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 KHN70398.1 - 4.3e-23 81.1 19.6 0.00033 21.4 0.0 9.7 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70398.1 - 1.4e-07 31.7 6.0 0.15 12.4 0.0 6.2 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain CTD_bind PF04818.13 KHN70399.1 - 4e-10 40.4 0.3 1e-09 39.1 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Pkinase PF00069.25 KHN70400.1 - 1.2e-70 237.9 0.1 1.5e-70 237.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70400.1 - 4.1e-41 141.0 0.0 5.5e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KHN70400.1 - 7e-08 32.1 0.0 1.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.18 KHN70400.1 - 8.9e-08 32.2 0.1 1.8e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 POLO box duplicated region APH PF01636.23 KHN70400.1 - 0.0012 18.8 0.0 0.03 14.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KHN70400.1 - 0.0012 17.9 0.1 0.0019 17.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KHN70400.1 - 0.022 14.4 0.7 0.62 9.6 0.1 2.3 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 KHN70400.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF5098 PF17023.5 KHN70401.1 - 3.1e-86 290.2 20.7 6.5e-86 289.1 20.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5098) Carbpep_Y_N PF05388.11 KHN70401.1 - 0.0098 16.4 0.6 0.093 13.3 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase Y pro-peptide DUF2459 PF09601.10 KHN70401.1 - 0.06 13.2 0.4 5.9 6.7 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2459) CK2S PF15011.6 KHN70401.1 - 0.16 11.9 2.4 0.73 9.7 0.2 2.8 2 1 0 2 2 2 0 Casein Kinase 2 substrate FlaC_arch PF05377.11 KHN70401.1 - 3.2 8.2 9.2 0.81 10.1 2.7 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PGM_PMM_I PF02878.16 KHN70402.1 - 5.1e-19 68.4 0.9 1.4e-08 34.5 0.0 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KHN70402.1 - 1.3e-09 38.6 0.0 5.4e-09 36.6 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KHN70402.1 - 9.5e-09 35.3 0.0 3.2e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KHN70402.1 - 0.002 18.3 0.0 0.0073 16.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Tfb2 PF03849.14 KHN70403.1 - 4.4e-52 177.2 4.3 6.5e-52 176.7 4.3 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KHN70403.1 - 2.8e-19 69.3 0.1 1.2e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KHN70403.1 - 0.0027 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nrap_D2 PF17403.2 KHN70403.1 - 0.087 12.6 0.1 0.3 10.8 0.1 1.9 2 1 0 2 2 2 0 Nrap protein PAP/OAS-like domain GlutR_N PF05201.15 KHN70403.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain Bromo_TP_like PF17027.5 KHN70403.1 - 0.17 12.0 2.4 0.97 9.6 2.2 2.3 1 1 0 1 1 1 0 Histone-fold protein BILBO1_N PF18281.1 KHN70403.1 - 0.22 11.9 1.0 8.1 6.9 0.0 2.8 3 0 0 3 3 3 0 BILBO1 N-terminal domain Pyr_redox_3 PF13738.6 KHN70404.1 - 0.0006 19.2 0.9 0.3 10.3 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KHN70404.1 - 0.00083 18.7 0.2 0.024 13.9 0.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KHN70404.1 - 0.037 12.9 0.1 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase eIF2_C PF09173.11 KHN70406.1 - 2.1e-25 88.8 0.1 2.1e-25 88.8 0.1 2.6 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KHN70406.1 - 3e-25 88.9 1.7 2.1e-24 86.1 1.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KHN70406.1 - 8.7e-09 35.6 1.4 1.3e-08 35.1 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KHN70406.1 - 2.5e-05 24.2 0.7 0.00033 20.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KHN70406.1 - 0.00023 21.2 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1319 PF07028.11 KHN70407.1 - 0.0073 16.5 0.6 0.02 15.1 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) Spc7 PF08317.11 KHN70407.1 - 0.014 14.3 3.4 0.022 13.6 3.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Thioredoxin PF00085.20 KHN70408.1 - 1.4e-06 28.2 0.1 2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KHN70408.1 - 0.0001 21.3 1.0 0.00077 18.5 1.0 1.9 1 1 0 1 1 1 1 Phosducin DIM1 PF02966.16 KHN70408.1 - 0.015 15.1 0.4 0.022 14.5 0.4 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 PRK PF00485.18 KHN70409.1 - 4e-08 33.2 1.5 2.4e-07 30.7 0.5 2.5 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 KHN70409.1 - 0.0049 16.3 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 KHN70409.1 - 0.0079 16.7 0.0 0.021 15.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 KHN70409.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.20 KHN70409.1 - 0.034 14.1 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 KHN70409.1 - 0.044 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 KHN70409.1 - 0.049 13.4 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CPT PF07931.12 KHN70409.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KHN70409.1 - 0.087 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KHN70409.1 - 0.095 13.2 0.2 0.14 12.6 0.2 1.4 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KHN70409.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Trp_ring PF18669.1 KHN70409.1 - 0.15 12.3 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain SecD_SecF PF02355.16 KHN70410.1 - 0.02 14.3 0.3 0.022 14.1 0.3 1.0 1 0 0 1 1 1 0 Protein export membrane protein TK PF00265.18 KHN70411.1 - 5.9e-37 127.2 0.1 7.1e-37 127.0 0.1 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_30 PF13604.6 KHN70411.1 - 0.0055 16.4 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN70411.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IMPDH PF00478.25 KHN70411.1 - 0.15 11.0 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain zf-RING_2 PF13639.6 KHN70412.1 - 1.3e-08 35.0 10.7 1.3e-08 35.0 10.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KHN70412.1 - 2.4e-05 24.1 6.6 2.4e-05 24.1 6.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KHN70412.1 - 2.7e-05 24.4 14.8 0.0004 20.6 14.8 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KHN70412.1 - 0.00011 22.1 3.7 0.00011 22.1 3.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KHN70412.1 - 0.00021 21.1 11.6 0.00057 19.7 11.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KHN70412.1 - 0.00031 20.6 10.4 0.00074 19.3 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KHN70412.1 - 0.003 17.2 3.5 0.003 17.2 3.5 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 KHN70412.1 - 0.027 14.4 10.0 0.082 12.9 10.0 1.9 1 0 0 1 1 1 0 zinc-RING finger domain ATP1G1_PLM_MAT8 PF02038.16 KHN70412.1 - 0.094 12.2 3.4 0.14 11.6 0.0 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family zf-ANAPC11 PF12861.7 KHN70412.1 - 0.27 11.3 9.2 1.2 9.2 9.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sdh_cyt PF01127.22 KHN70412.1 - 1 9.4 11.2 0.77 9.8 1.3 2.6 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-C3HC4_4 PF15227.6 KHN70412.1 - 5.7 7.2 20.1 0.053 13.7 9.2 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KHN70412.1 - 5.8 6.9 14.2 10 6.1 12.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Myb_DNA-binding PF00249.31 KHN70413.1 - 3.8e-07 30.2 0.1 8.8e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KHN70413.1 - 1.5e-06 28.3 0.2 9e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KHN70413.1 - 0.0078 16.4 3.8 0.012 15.8 2.7 2.0 2 1 0 2 2 2 1 SANT/Myb-like domain of DAMP1 MCRS_N PF13325.6 KHN70413.1 - 0.014 15.4 0.1 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein Glyco_transf_20 PF00982.21 KHN70416.1 - 3.6e-135 451.3 0.3 7.8e-135 450.2 0.3 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KHN70416.1 - 0.0011 18.7 0.7 0.016 14.9 0.3 2.3 2 0 0 2 2 2 1 Starch synthase catalytic domain DUF3747 PF12565.8 KHN70416.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) RICTOR_V PF14668.6 KHN70417.1 - 0.094 13.0 1.7 0.58 10.4 0.4 2.6 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 ATP1G1_PLM_MAT8 PF02038.16 KHN70418.1 - 0.13 11.7 0.1 0.54 9.7 0.1 2.1 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family zf-CCCH PF00642.24 KHN70419.1 - 1e-17 63.5 16.1 5.9e-09 35.6 3.7 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KHN70419.1 - 5.9e-09 35.7 14.4 8.4e-06 25.7 4.6 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KHN70419.1 - 3.2e-07 30.0 12.6 0.0013 18.5 1.9 2.8 2 0 0 2 2 2 2 CCCH-type zinc finger ARD PF03079.14 KHN70419.1 - 0.008 16.4 0.8 0.02 15.1 0.8 1.7 1 0 0 1 1 1 1 ARD/ARD' family N6_Mtase PF02384.16 KHN70419.1 - 0.017 14.4 0.4 0.025 13.9 0.4 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Torus PF16131.5 KHN70419.1 - 0.2 12.4 17.3 1 10.1 2.3 2.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 KHN70419.1 - 0.46 11.0 18.4 0.43 11.1 1.9 3.9 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 KHN70420.1 - 5e-09 35.8 0.1 1.2e-07 31.4 0.1 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.27 KHN70421.1 - 0.0018 18.8 0.1 0.028 14.9 0.1 2.4 2 0 0 2 2 2 1 PCI domain HAT_KAT11 PF08214.11 KHN70422.1 - 2.8e-06 26.8 0.4 0.00059 19.2 0.0 2.4 1 1 1 2 2 2 2 Histone acetylation protein Trehalose_PPase PF02358.16 KHN70423.1 - 2.4e-28 98.9 0.0 3.9e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.21 KHN70423.1 - 1e-12 47.5 0.1 1.7e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Hydrolase_3 PF08282.12 KHN70423.1 - 0.0048 16.7 0.1 4.2 7.0 0.0 3.0 1 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Biotin_lipoyl PF00364.22 KHN70423.1 - 0.17 11.8 0.0 0.51 10.2 0.0 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme EndoU_bacteria PF14436.6 KHN70425.1 - 0.16 12.3 0.9 1.7 9.0 0.2 2.1 1 1 1 2 2 2 0 Bacterial EndoU nuclease Tir_receptor_C PF07489.11 KHN70425.1 - 0.21 11.6 0.2 0.28 11.1 0.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus CopK PF11525.8 KHN70427.1 - 0.047 13.3 2.1 8.4 6.1 0.9 2.5 2 0 0 2 2 2 0 Copper resistance protein K Ribosomal_L7Ae PF01248.26 KHN70428.1 - 4.1e-11 42.4 1.4 5.6e-11 42.0 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glutaredoxin PF00462.24 KHN70428.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin PF00085.20 KHN70429.1 - 2.7e-08 33.7 0.5 4.4e-08 33.0 0.5 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KHN70429.1 - 0.0013 19.0 0.1 2.5 8.5 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KHN70429.1 - 0.0032 17.9 0.5 0.013 15.9 0.5 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KHN70429.1 - 0.019 15.1 0.1 0.031 14.5 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like UQ_con PF00179.26 KHN70430.1 - 1.1e-37 128.9 0.3 1.2e-37 128.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KHN70430.1 - 0.00091 18.9 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KHN70430.1 - 0.063 13.6 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 RWD domain HTH_3 PF01381.22 KHN70432.1 - 0.0021 18.1 0.3 0.0035 17.3 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix DUF4136 PF13590.6 KHN70432.1 - 0.078 13.6 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) TBPIP PF07106.13 KHN70433.1 - 1.4e-17 63.3 0.4 3.5e-17 62.1 0.4 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 KHN70433.1 - 0.00043 20.3 0.3 0.0014 18.7 0.3 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain DASH_Dad2 PF08654.10 KHN70433.1 - 0.0067 16.8 1.6 0.013 15.9 1.5 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 Laminin_II PF06009.12 KHN70433.1 - 0.017 15.2 5.1 0.26 11.3 1.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Lebercilin PF15619.6 KHN70433.1 - 0.027 14.1 5.8 0.038 13.7 5.8 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TMEM70 PF06979.12 KHN70433.1 - 0.057 13.8 0.0 0.092 13.2 0.0 1.2 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex BUD22 PF09073.10 KHN70433.1 - 0.11 11.8 2.4 0.13 11.5 2.4 1.1 1 0 0 1 1 1 0 BUD22 VasL PF12486.8 KHN70433.1 - 0.14 12.0 0.1 0.37 10.6 0.0 1.9 1 1 0 1 1 1 0 Type VI secretion system, EvfB, or VasL Rho_Binding PF08912.11 KHN70433.1 - 0.17 12.7 9.9 0.14 13.0 1.3 2.4 1 1 1 2 2 2 0 Rho Binding KxDL PF10241.9 KHN70433.1 - 0.23 11.8 2.5 0.61 10.4 1.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Spc24 PF08286.11 KHN70433.1 - 0.27 11.5 10.0 1.3 9.3 3.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TFIIE_beta PF02186.15 KHN70433.1 - 0.41 11.0 3.8 6.3 7.2 0.3 2.7 3 0 0 3 3 3 0 TFIIE beta subunit core domain TMPIT PF07851.13 KHN70433.1 - 0.62 9.3 5.7 0.38 9.9 3.2 1.7 1 1 0 2 2 2 0 TMPIT-like protein FlaC_arch PF05377.11 KHN70433.1 - 0.84 10.1 9.9 12 6.4 7.1 3.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KHN70433.1 - 4.9 7.0 10.5 10 6.0 1.6 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF1189 PF06691.11 KHN70433.1 - 8.8 5.8 6.9 8.4 5.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) XhlA PF10779.9 KHN70433.1 - 9.8 6.5 11.2 13 6.1 0.6 2.8 1 1 1 2 2 2 0 Haemolysin XhlA Aldo_ket_red PF00248.21 KHN70434.1 - 3.1e-43 148.0 0.0 1e-41 143.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family zf-RING_4 PF14570.6 KHN70435.1 - 0.013 15.3 0.6 0.018 14.8 0.6 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LisH PF08513.11 KHN70436.1 - 1.4e-07 31.2 0.4 2.8e-07 30.3 0.4 1.5 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 KHN70436.1 - 2.2e-06 27.3 3.5 0.0066 15.8 0.7 3.1 1 1 2 3 3 3 3 WD40-like domain WD40 PF00400.32 KHN70436.1 - 0.0054 17.5 21.8 0.94 10.5 0.4 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF4428 PF14471.6 KHN70436.1 - 0.043 13.8 1.6 0.078 12.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) UQ_con PF00179.26 KHN70438.1 - 6e-34 116.7 0.0 7.2e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EB1 PF03271.17 KHN70440.1 - 2.9e-07 30.6 6.6 1.2e-06 28.6 4.9 2.6 2 0 0 2 2 2 1 EB1-like C-terminal motif DUF1002 PF06207.11 KHN70440.1 - 0.0058 16.2 10.2 0.02 14.5 10.2 1.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1002) DUF5355 PF17306.2 KHN70440.1 - 0.0089 15.1 7.0 0.012 14.6 7.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5355) NOT2_3_5 PF04153.18 KHN70441.1 - 2.3e-12 47.1 0.9 2.9e-12 46.8 0.9 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DELLA PF12041.8 KHN70441.1 - 0.065 13.1 0.5 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Sec15 PF04091.12 KHN70442.1 - 6.9e-05 22.4 0.8 0.00027 20.5 0.7 2.1 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF4477 PF14780.6 KHN70442.1 - 0.0097 15.6 1.0 0.0097 15.6 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) DUF3605 PF12239.8 KHN70442.1 - 0.03 14.7 2.0 0.042 14.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3605) Serum_albumin PF00273.20 KHN70442.1 - 0.48 10.2 3.5 0.86 9.3 0.2 2.3 2 0 0 2 2 2 0 Serum albumin family ERCC3_RAD25_C PF16203.5 KHN70443.1 - 6.3e-113 376.0 0.1 9.7e-113 375.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KHN70443.1 - 8.2e-29 100.3 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KHN70443.1 - 1.1e-16 61.3 0.0 2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KHN70443.1 - 9.5e-12 45.2 0.0 2.9e-11 43.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KHN70443.1 - 3.4e-06 26.0 0.1 5.8e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KHN70443.1 - 8.7e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1373 PF07117.11 KHN70444.1 - 0.0056 16.7 3.5 0.01 15.9 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1373) Methyltr_RsmB-F PF01189.17 KHN70445.1 - 2.5e-61 206.8 0.0 4e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KHN70445.1 - 3.6e-12 46.6 0.0 8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 KHN70445.1 - 2.4e-07 31.1 0.1 4.5e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.10 KHN70445.1 - 0.00057 19.6 0.0 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 KHN70445.1 - 0.00085 19.1 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KHN70445.1 - 0.031 13.8 0.6 0.83 9.2 0.6 2.2 1 1 0 1 1 1 0 Methyltransferase small domain POR PF01558.18 KHN70445.1 - 0.031 14.3 0.0 0.084 12.9 0.0 1.7 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Methyltransf_25 PF13649.6 KHN70445.1 - 0.032 14.9 0.3 0.38 11.5 0.3 2.4 1 1 0 1 1 1 0 Methyltransferase domain Suv3_N PF18114.1 KHN70445.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Myb_DNA-binding PF00249.31 KHN70446.1 - 4e-13 49.3 1.5 0.00038 20.6 0.5 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KHN70446.1 - 1.8e-07 31.3 4.4 0.00099 19.3 0.4 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KHN70446.1 - 0.0023 17.8 9.5 0.02 14.7 0.2 3.1 1 1 1 2 2 2 2 Myb DNA-binding like GTP_EFTU_D4 PF14578.6 KHN70446.1 - 0.084 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 zf-rbx1 PF12678.7 KHN70447.1 - 4.7e-23 81.2 13.5 6.1e-23 80.9 13.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KHN70447.1 - 2.4e-16 59.6 9.7 2.8e-16 59.3 9.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KHN70447.1 - 9.6e-08 32.2 8.0 9.6e-08 32.2 8.0 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KHN70447.1 - 2.2e-05 24.2 14.2 0.0051 16.6 14.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 KHN70447.1 - 0.0007 19.7 4.4 0.00092 19.4 4.4 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C3HC4 PF00097.25 KHN70447.1 - 0.0012 18.6 12.7 0.0098 15.7 12.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KHN70447.1 - 0.014 15.1 10.7 0.52 10.1 10.7 2.3 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KHN70447.1 - 0.016 14.8 3.9 0.016 14.8 3.9 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KHN70447.1 - 0.036 14.2 8.6 0.061 13.5 8.6 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF3797 PF12677.7 KHN70447.1 - 0.041 13.8 2.7 0.041 13.8 2.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 KHN70447.1 - 0.16 12.0 7.7 0.54 10.3 7.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KHN70447.1 - 0.22 11.4 11.8 6.1 6.8 0.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KHN70447.1 - 1 9.4 12.5 21 5.2 12.8 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 KHN70447.1 - 2.2 8.7 13.9 19 5.7 13.9 2.1 1 1 0 1 1 1 0 RING-like domain KxDL PF10241.9 KHN70448.1 - 0.01 16.1 4.6 0.019 15.2 4.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein T6SS_HCP PF05638.12 KHN70448.1 - 0.085 13.3 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Type VI secretion system effector, Hcp Bap31_Bap29_C PF18035.1 KHN70448.1 - 0.17 11.9 4.1 3.9 7.5 2.8 2.6 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain FTCD_C PF04961.12 KHN70448.1 - 0.27 11.0 6.6 0.45 10.3 6.6 1.5 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase UPF0242 PF06785.11 KHN70448.1 - 2.9 7.9 11.5 4.5 7.3 11.5 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 KHN70448.1 - 6.8 5.8 8.6 2.5 7.3 6.3 1.4 1 1 0 1 1 1 0 TMPIT-like protein DUF5092 PF17010.5 KHN70449.1 - 4.5e-06 26.7 0.1 7.6e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5092) AbrB PF05145.12 KHN70449.1 - 0.0075 15.3 0.6 0.011 14.7 0.6 1.2 1 0 0 1 1 1 1 Transition state regulatory protein AbrB Cyt-b5 PF00173.28 KHN70450.1 - 4.4e-21 74.8 0.0 5.1e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RtcB PF01139.17 KHN70451.1 - 3.8e-133 444.6 0.1 4.5e-133 444.4 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB RPN5_C PF18098.1 KHN70451.1 - 0.16 12.1 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain Peptidase_S8 PF00082.22 KHN70452.1 - 1.3e-33 116.6 3.2 7.2e-33 114.1 3.2 2.1 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KHN70452.1 - 0.0001 22.9 0.1 0.00028 21.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase inhibitor I9 Myb_DNA-binding PF00249.31 KHN70453.1 - 4.3e-05 23.6 0.1 0.00017 21.7 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KHN70453.1 - 0.031 14.5 0.1 0.077 13.3 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain HTH_19 PF12844.7 KHN70453.1 - 0.044 13.8 0.2 0.89 9.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Cyclin_N PF00134.23 KHN70454.1 - 0.0059 16.4 0.2 0.0088 15.8 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SMC_N PF02463.19 KHN70455.1 - 3.5e-60 203.2 0.0 2.2e-59 200.5 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KHN70455.1 - 4.2e-15 56.1 0.1 2.2e-14 53.8 0.0 2.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KHN70455.1 - 1.1e-11 45.2 0.2 5.2e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KHN70455.1 - 2.9e-10 41.0 1.5 2.9e-10 41.0 1.5 4.1 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.6 KHN70455.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Destabilase PF05497.12 KHN70455.1 - 0.18 12.2 3.4 0.77 10.1 0.4 2.6 2 0 0 2 2 2 0 Destabilase Peptidase_S28 PF05577.12 KHN70455.1 - 0.31 9.8 1.0 0.53 9.0 1.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 ABC_tran PF00005.27 KHN70455.1 - 0.34 11.4 9.1 13 6.3 0.0 4.5 4 1 0 4 4 4 0 ABC transporter MS_channel PF00924.18 KHN70456.1 - 7.1e-15 55.1 1.2 1.3e-14 54.2 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF2973 PF11189.8 KHN70456.1 - 0.076 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) DUF1206 PF06724.11 KHN70456.1 - 0.14 12.2 2.0 1.5 8.9 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) GrpB PF04229.14 KHN70456.1 - 0.16 12.2 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 GrpB protein Rad17 PF03215.15 KHN70457.1 - 1.7e-08 34.6 0.0 2.7e-07 30.7 0.0 2.2 1 1 1 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 KHN70457.1 - 8.3e-07 29.5 0.1 2.3e-06 28.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KHN70457.1 - 0.00012 22.7 0.1 0.00028 21.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KHN70457.1 - 0.0014 18.9 0.7 0.012 15.9 0.1 2.6 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 KHN70457.1 - 0.0017 18.1 0.0 0.0079 15.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KHN70457.1 - 0.002 17.3 0.0 0.0057 15.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 KHN70457.1 - 0.0027 17.6 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 KHN70457.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 KHN70457.1 - 0.0086 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KHN70457.1 - 0.0086 16.1 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KHN70457.1 - 0.01 16.2 0.1 0.047 14.1 0.1 2.0 2 1 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 KHN70457.1 - 0.011 16.1 0.0 0.071 13.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DNA_pol3_delta PF06144.13 KHN70457.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.8 1 1 0 1 1 1 0 DNA polymerase III, delta subunit AAA_7 PF12775.7 KHN70457.1 - 0.023 14.2 0.0 0.064 12.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KHN70457.1 - 0.04 14.4 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KHN70457.1 - 0.042 14.0 0.1 0.088 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KHN70457.1 - 0.048 13.2 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN70457.1 - 0.048 13.4 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KHN70457.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_2 PF07724.14 KHN70457.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 KHN70457.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 KHN70457.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.6 KHN70457.1 - 0.24 11.2 0.2 0.42 10.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PI_PP_I PF18363.1 KHN70458.1 - 7.7 6.8 10.6 0.31 11.3 1.9 2.9 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain SAS-6_N PF16531.5 KHN70459.1 - 1.1e-15 58.0 0.7 2.7e-15 56.7 0.7 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal KASH_CCD PF14662.6 KHN70459.1 - 3.2e-08 33.6 39.2 0.00036 20.4 17.7 2.7 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH BST2 PF16716.5 KHN70459.1 - 0.00067 20.2 28.1 0.061 13.9 7.0 3.3 1 1 2 3 3 3 2 Bone marrow stromal antigen 2 GAS PF13851.6 KHN70459.1 - 0.0014 18.0 11.8 0.0014 18.0 11.8 3.5 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 KHN70459.1 - 0.0016 19.1 32.8 0.48 11.1 7.8 4.3 1 1 4 5 5 5 3 Initiation control protein YabA TPR_MLP1_2 PF07926.12 KHN70459.1 - 0.0067 16.5 36.0 0.65 10.1 11.5 3.7 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 KHN70459.1 - 0.023 14.9 16.1 0.023 14.9 16.1 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Taxilin PF09728.9 KHN70459.1 - 0.027 13.7 38.8 0.41 9.8 34.3 2.8 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF724 PF05266.14 KHN70459.1 - 0.058 13.2 31.5 0.064 13.1 9.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 KHN70459.1 - 0.063 12.1 36.3 0.052 12.4 19.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein CortBP2 PF09727.9 KHN70459.1 - 0.068 13.1 39.6 0.43 10.5 5.0 3.2 2 1 1 3 3 3 0 Cortactin-binding protein-2 DUF2353 PF09789.9 KHN70459.1 - 0.069 12.5 33.0 0.66 9.3 10.0 2.2 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) UPF0242 PF06785.11 KHN70459.1 - 0.07 13.2 38.5 0.45 10.6 8.3 3.2 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Spectrin PF00435.21 KHN70459.1 - 0.071 13.6 22.8 1.1 9.7 0.8 3.3 1 1 2 3 3 3 0 Spectrin repeat bZIP_1 PF00170.21 KHN70459.1 - 0.083 13.0 44.1 0.57 10.3 2.4 6.3 2 1 4 6 6 6 0 bZIP transcription factor HAP1_N PF04849.13 KHN70459.1 - 0.1 11.8 32.9 0.59 9.3 10.6 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region ADIP PF11559.8 KHN70459.1 - 0.11 12.6 35.8 1 9.4 14.1 3.0 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KHN70459.1 - 0.11 12.7 34.8 0.55 10.4 31.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 KHN70459.1 - 0.26 11.7 37.6 0.07 13.5 8.0 3.6 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2937 PF11157.8 KHN70459.1 - 0.26 11.0 1.8 0.4 10.4 0.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2937) GIT_CC PF16559.5 KHN70459.1 - 0.28 11.1 19.7 0.57 10.1 1.1 5.3 3 2 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor JIP_LZII PF16471.5 KHN70459.1 - 0.43 10.8 30.0 1 9.6 0.4 4.7 3 1 2 5 5 4 0 JNK-interacting protein leucine zipper II TMCO5 PF14992.6 KHN70459.1 - 0.86 9.1 38.5 3.4 7.2 18.8 2.8 1 1 1 2 2 2 0 TMCO5 family Leu_zip PF15294.6 KHN70459.1 - 0.86 9.1 35.4 7.4 6.0 23.8 2.3 1 1 1 2 2 2 0 Leucine zipper APG6_N PF17675.1 KHN70459.1 - 1.2 9.7 41.5 2.2 8.8 16.0 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 KHN70459.1 - 1.2 9.2 15.3 0.73 9.9 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 KHN70459.1 - 1.2 9.6 30.6 7 7.1 4.5 4.7 1 1 3 4 4 4 0 Csm1 N-terminal domain TSC22 PF01166.18 KHN70459.1 - 1.3 9.4 24.7 5 7.5 2.4 5.6 3 1 2 6 6 5 0 TSC-22/dip/bun family RPW8 PF05659.11 KHN70459.1 - 1.4 8.6 19.1 4.5 7.0 3.7 3.2 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.9 KHN70459.1 - 1.8 8.9 25.2 2.1 8.7 13.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KHN70459.1 - 1.8 7.8 21.0 4.1 6.6 5.0 3.1 2 1 2 4 4 3 0 Protein of unknown function (DUF3450) DivIC PF04977.15 KHN70459.1 - 1.8 8.4 36.9 0.4 10.5 3.0 5.8 2 1 4 6 6 6 0 Septum formation initiator Fez1 PF06818.15 KHN70459.1 - 1.9 8.9 34.2 3.1 8.2 15.7 2.2 1 1 1 2 2 2 0 Fez1 NPV_P10 PF05531.12 KHN70459.1 - 2.3 8.7 6.5 1.2 9.7 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 KHN70459.1 - 2.7 8.2 36.3 9.9 6.4 18.8 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 HOOK PF05622.12 KHN70459.1 - 2.9 5.9 39.6 6.2 4.8 39.6 1.4 1 1 0 1 1 1 0 HOOK protein Cep57_CLD_2 PF14197.6 KHN70459.1 - 2.9 8.0 38.1 3.5 7.8 5.6 4.7 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 MAD PF05557.13 KHN70459.1 - 3 6.1 36.3 6.8 4.9 36.2 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein TMPIT PF07851.13 KHN70459.1 - 3.5 6.8 24.4 6.6 5.9 12.3 2.3 1 1 1 2 2 2 0 TMPIT-like protein FlxA PF14282.6 KHN70459.1 - 3.7 7.6 21.0 1.9 8.5 4.0 2.7 2 1 0 2 2 2 0 FlxA-like protein HemX PF04375.14 KHN70459.1 - 4 6.6 18.3 4.6 6.4 9.6 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FapA PF03961.13 KHN70459.1 - 4.1 5.9 30.5 0.76 8.3 15.3 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Laminin_II PF06009.12 KHN70459.1 - 4.9 7.2 24.7 17 5.4 9.9 2.7 1 1 1 2 2 2 0 Laminin Domain II Syntaxin-6_N PF09177.11 KHN70459.1 - 5.3 7.7 21.7 4.2 8.0 7.4 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SOAR PF16533.5 KHN70459.1 - 5.6 7.0 16.3 0.042 13.8 4.4 2.8 1 1 1 2 2 1 0 STIM1 Orai1-activating region SlyX PF04102.12 KHN70459.1 - 5.9 7.6 17.7 19 6.0 0.3 5.3 1 1 5 6 6 5 0 SlyX ZapB PF06005.12 KHN70459.1 - 8.1 7.0 40.1 0.25 11.8 5.9 4.7 1 1 3 4 4 3 0 Cell division protein ZapB Dynamin_N PF00350.23 KHN70460.1 - 6.1e-39 133.8 0.1 1.2e-38 132.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KHN70460.1 - 2.1e-34 119.1 3.9 5.1e-34 117.8 1.3 2.4 2 1 0 2 2 2 1 Dynamin central region GED PF02212.18 KHN70460.1 - 7.6e-09 35.6 1.2 2.3e-08 34.0 1.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KHN70460.1 - 6.2e-06 26.3 0.0 1.7e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ScsC_N PF18312.1 KHN70460.1 - 2.1 8.2 5.0 2.4 8.1 0.2 3.2 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain Guanylate_kin PF00625.21 KHN70461.1 - 3.2e-34 118.2 0.0 3.6e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KHN70461.1 - 6.5e-06 26.7 0.3 1.6e-05 25.4 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KHN70461.1 - 0.00047 19.9 0.2 0.00084 19.0 0.2 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KHN70461.1 - 0.0079 16.5 0.0 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KHN70461.1 - 0.0095 16.5 0.1 0.016 15.7 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 KHN70461.1 - 0.01 16.3 0.3 0.026 14.9 0.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain Thymidylate_kin PF02223.17 KHN70461.1 - 0.01 15.5 0.3 0.09 12.4 0.0 2.2 2 1 1 3 3 3 0 Thymidylate kinase AAA_33 PF13671.6 KHN70461.1 - 0.02 15.0 2.2 1.4 9.1 0.5 3.1 2 2 2 4 4 4 0 AAA domain AAA_5 PF07728.14 KHN70461.1 - 0.033 14.2 0.0 0.073 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KHN70461.1 - 0.052 13.5 1.0 0.12 12.3 0.3 1.8 2 0 0 2 2 2 0 NTPase CoaE PF01121.20 KHN70461.1 - 0.052 13.2 0.1 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_7 PF12775.7 KHN70461.1 - 0.054 13.0 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_C39 PF03412.15 KHN70461.1 - 0.062 13.1 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family AAA_17 PF13207.6 KHN70461.1 - 0.063 13.7 1.2 12 6.3 0.3 2.4 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KHN70461.1 - 0.088 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 KHN70461.1 - 0.09 13.3 2.3 0.2 12.1 2.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KHN70461.1 - 0.15 11.7 0.3 0.35 10.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KHN70461.1 - 0.22 11.4 0.5 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase T2SSE PF00437.20 KHN70461.1 - 0.26 10.3 0.1 0.41 9.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KHN70461.1 - 0.54 10.0 1.7 1.3 8.7 0.2 2.3 2 1 1 3 3 3 0 Cytidylate kinase AAA PF00004.29 KHN70462.1 - 1.5e-99 329.6 0.0 2.5e-48 163.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN70462.1 - 4.5e-23 80.8 0.9 1.1e-11 44.3 0.3 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KHN70462.1 - 4.7e-15 55.7 0.0 1e-06 28.6 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KHN70462.1 - 4.4e-13 50.0 0.0 0.00036 20.9 0.0 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 KHN70462.1 - 5.7e-13 49.3 0.0 6.9e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KHN70462.1 - 3.4e-11 43.3 0.1 4.9e-05 23.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KHN70462.1 - 2.3e-10 40.9 2.8 0.045 14.0 0.0 4.8 3 2 2 5 5 4 2 AAA domain AAA_33 PF13671.6 KHN70462.1 - 3.2e-10 40.3 0.0 0.00018 21.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KHN70462.1 - 4.4e-09 36.0 0.0 0.002 17.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KHN70462.1 - 5e-09 36.3 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KHN70462.1 - 1.2e-07 31.7 0.6 0.022 14.5 0.0 3.7 4 1 1 5 5 5 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KHN70462.1 - 1.3e-07 31.9 0.0 0.012 15.9 0.0 3.1 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 KHN70462.1 - 2e-07 31.6 0.0 0.0091 16.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KHN70462.1 - 4.2e-07 29.5 0.4 0.029 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KHN70462.1 - 1.6e-06 28.4 0.0 0.17 12.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KHN70462.1 - 2.1e-06 27.4 1.7 0.48 10.0 0.1 3.7 2 2 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 KHN70462.1 - 4.7e-06 25.9 0.3 0.021 13.9 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 KHN70462.1 - 6.6e-06 26.7 0.1 0.16 12.5 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 KHN70462.1 - 6.9e-06 26.1 0.0 0.0077 16.1 0.0 2.8 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_7 PF12775.7 KHN70462.1 - 7.3e-06 25.6 0.0 0.15 11.5 0.0 3.0 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KHN70462.1 - 1.5e-05 24.9 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 KHN70462.1 - 1.7e-05 24.9 0.0 4.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain DUF815 PF05673.13 KHN70462.1 - 3.1e-05 23.3 0.0 0.037 13.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KHN70462.1 - 3.7e-05 23.5 0.1 0.23 11.1 0.0 3.6 2 2 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.10 KHN70462.1 - 3.8e-05 23.6 0.0 0.00072 19.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 KHN70462.1 - 5.3e-05 23.7 0.0 0.45 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KHN70462.1 - 6.6e-05 22.9 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KHN70462.1 - 7.1e-05 22.9 0.0 0.074 13.2 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 KHN70462.1 - 9.7e-05 22.4 0.0 0.0067 16.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 KHN70462.1 - 0.00012 22.1 0.1 0.94 9.3 0.0 3.0 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KHN70462.1 - 0.00024 20.4 0.2 0.89 8.8 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin NACHT PF05729.12 KHN70462.1 - 0.00025 21.0 0.3 0.44 10.5 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 KHN70462.1 - 0.00033 20.5 0.0 0.59 10.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KHN70462.1 - 0.00041 19.8 3.4 1 8.7 0.0 4.0 5 0 0 5 5 4 2 KaiC NB-ARC PF00931.22 KHN70462.1 - 0.00045 19.5 0.0 0.72 9.0 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain Viral_helicase1 PF01443.18 KHN70462.1 - 0.00068 19.4 0.0 0.091 12.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KHN70462.1 - 0.00079 18.9 0.8 1.1 8.7 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 KHN70462.1 - 0.0016 17.8 0.0 0.27 10.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 KHN70462.1 - 0.0037 17.2 0.1 3.3 7.6 0.0 3.3 3 1 0 3 3 3 1 Rad17 P-loop domain AAA_19 PF13245.6 KHN70462.1 - 0.0053 17.1 0.9 1.8 8.9 0.2 2.9 2 1 1 3 3 2 1 AAA domain NTPase_1 PF03266.15 KHN70462.1 - 0.013 15.4 1.9 5.5 6.9 0.0 4.1 5 0 0 5 5 3 0 NTPase Cytidylate_kin2 PF13189.6 KHN70462.1 - 0.044 13.9 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_11 PF13086.6 KHN70462.1 - 0.064 13.0 5.7 1.3 8.7 0.1 3.3 2 1 2 4 4 4 0 AAA domain AAA_30 PF13604.6 KHN70462.1 - 0.076 12.7 1.1 3.9 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KHN70462.1 - 0.14 11.6 0.0 11 5.4 0.0 3.2 4 0 0 4 4 3 0 Bacterial TniB protein Zot PF05707.12 KHN70462.1 - 0.19 11.3 0.1 3.6 7.2 0.0 2.9 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_23 PF13476.6 KHN70462.1 - 9.6 6.6 7.9 30 5.1 0.1 3.6 4 0 0 4 4 4 0 AAA domain MS_channel PF00924.18 KHN70463.1 - 5.2e-12 45.8 0.3 5.2e-12 45.8 0.3 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel C2 PF00168.30 KHN70464.1 - 5.2e-24 84.5 2.3 1.4e-12 47.8 0.0 5.7 5 1 1 6 6 6 3 C2 domain SMP_LBD PF17047.5 KHN70464.1 - 0.054 13.0 0.5 5.3 6.5 0.4 2.6 1 1 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain CEP76-C2 PF15627.6 KHN70464.1 - 0.16 11.5 0.2 1.1 8.8 0.0 2.3 3 0 0 3 3 3 0 CEP76 C2 domain Glycos_trans_3N PF02885.17 KHN70465.1 - 0.033 14.0 0.1 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain EF-hand_6 PF13405.6 KHN70465.1 - 0.039 13.9 3.3 0.43 10.6 0.1 3.0 4 0 0 4 4 4 0 EF-hand domain SusE PF14292.6 KHN70465.1 - 0.045 14.0 0.7 0.25 11.6 0.4 2.2 1 1 1 2 2 2 0 SusE outer membrane protein EF-hand_7 PF13499.6 KHN70465.1 - 0.067 13.6 0.2 3.3 8.2 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair DUF3860 PF12976.7 KHN70465.1 - 0.082 12.9 0.9 0.38 10.8 0.2 2.0 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) Prefoldin_3 PF13758.6 KHN70465.1 - 0.083 13.0 0.5 0.34 11.0 0.1 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF5531 PF17671.1 KHN70465.1 - 0.09 12.7 1.1 1.4 8.8 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5531) CS PF04969.16 KHN70467.1 - 1.2e-09 39.0 0.1 1.7e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 CS domain Coatomer_WDAD PF04053.14 KHN70468.1 - 2.1e-34 119.3 0.0 3.9e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KHN70468.1 - 2.7e-32 110.3 11.6 3e-08 34.2 0.7 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat COPI_C PF06957.11 KHN70468.1 - 3.8e-10 39.1 0.1 3.8e-10 39.1 0.1 1.9 2 1 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus ANAPC4_WD40 PF12894.7 KHN70468.1 - 1e-06 28.9 0.0 1.5 9.1 0.0 4.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KHN70469.1 - 1.6e-26 92.0 14.3 8.1e-05 23.3 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40_like PF17005.5 KHN70469.1 - 3e-10 39.9 3.5 4e-08 33.0 0.4 3.2 2 1 1 4 4 4 2 WD40-like domain ANAPC4_WD40 PF12894.7 KHN70469.1 - 5.6e-09 36.2 1.3 0.018 15.3 0.1 4.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KHN70469.1 - 0.0013 18.3 0.0 0.011 15.4 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain CPSF_A PF03178.15 KHN70469.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region eIF2A PF08662.11 KHN70469.1 - 0.045 13.6 0.2 2.5 7.9 0.0 2.8 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A IF4E PF01652.18 KHN70469.1 - 0.089 12.6 1.0 0.31 10.8 0.5 1.9 2 0 0 2 2 2 0 Eukaryotic initiation factor 4E Nup160 PF11715.8 KHN70469.1 - 0.11 11.1 1.3 25 3.3 0.0 3.4 2 1 2 4 4 4 0 Nucleoporin Nup120/160 DUF4934 PF16288.5 KHN70469.1 - 0.13 12.2 0.3 16 5.5 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4934) Mcl1_mid PF12341.8 KHN70469.1 - 0.21 10.9 0.6 4.8 6.4 0.1 2.6 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Frataxin_Cyay PF01491.16 KHN70470.1 - 2e-23 82.5 0.2 2.2e-23 82.4 0.2 1.0 1 0 0 1 1 1 1 Frataxin-like domain Pkinase PF00069.25 KHN70471.1 - 9.3e-51 172.7 1.4 3.1e-50 171.0 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70471.1 - 2.3e-22 79.6 0.1 7e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.22 KHN70471.1 - 4.9e-10 39.1 2.1 4.9e-10 39.1 2.1 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.6 KHN70471.1 - 3.8e-07 29.7 0.0 8.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like HR1 PF02185.16 KHN70471.1 - 0.00021 21.3 3.8 0.00021 21.3 3.8 3.3 3 1 1 4 4 2 1 Hr1 repeat Kdo PF06293.14 KHN70471.1 - 0.0038 16.6 0.0 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KHN70471.1 - 0.0041 17.1 0.2 0.015 15.2 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family PHD_2 PF13831.6 KHN70471.1 - 0.0079 15.7 2.6 0.021 14.4 2.6 1.8 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 KHN70471.1 - 0.057 13.6 0.4 0.057 13.6 0.4 3.4 3 1 1 4 4 4 0 FYVE-type zinc finger BLUF PF04940.12 KHN70471.1 - 0.066 13.3 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 1 0 Sensors of blue-light using FAD SLATT_1 PF18181.1 KHN70471.1 - 0.1 12.5 0.5 0.24 11.3 0.5 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PHD PF00628.29 KHN70471.1 - 0.11 12.4 4.4 0.29 11.1 4.4 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 KHN70471.1 - 0.31 11.4 3.8 1 9.7 3.8 1.9 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 KHN70471.1 - 0.6 10.0 12.5 0.032 14.2 2.3 2.8 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 KHN70471.1 - 7.5 7.0 11.0 0.11 12.8 3.1 2.1 3 0 0 3 3 2 0 C1 domain Hydrolase_4 PF12146.8 KHN70472.1 - 8.1e-07 28.5 0.0 2.5e-06 26.9 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KHN70472.1 - 1.2e-06 29.4 0.0 1.5e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KHN70472.1 - 5.5e-06 25.5 0.0 8.2e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KHN70472.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KHN70472.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF900 PF05990.12 KHN70472.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 KHN70472.1 - 0.069 12.6 0.0 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family TFIID-31kDa PF02291.15 KHN70473.1 - 1.5e-35 121.9 0.0 1.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 KHN70473.1 - 1.5e-08 34.9 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KHN70473.1 - 8.5e-07 28.9 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.17 KHN70473.1 - 0.00026 21.1 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KHN70473.1 - 0.00027 21.3 0.0 0.00039 20.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KHN70473.1 - 0.0058 16.7 0.0 0.0087 16.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Vps5 PF09325.10 KHN70474.1 - 0.0028 17.3 1.2 0.0028 17.3 1.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like ICMT PF04140.14 KHN70475.1 - 5e-06 26.8 0.2 5e-06 26.8 0.2 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KHN70475.1 - 7e-06 26.4 0.9 7e-06 26.4 0.9 2.3 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KHN70475.1 - 7.1e-06 25.7 1.6 8.6e-06 25.4 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KHN70475.1 - 0.0033 17.0 0.5 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 NnrU protein Gar1 PF04410.14 KHN70476.1 - 1.1e-14 54.5 0.1 1.1e-14 54.5 0.1 1.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF1366 PF07104.11 KHN70476.1 - 0.004 16.8 0.1 0.0085 15.8 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1366) F_actin_bind PF08919.10 KHN70476.1 - 0.0076 16.3 0.0 0.0076 16.3 0.0 1.6 2 0 0 2 2 2 1 F-actin binding Septin PF00735.18 KHN70477.1 - 2.9e-59 200.7 0.0 5.4e-59 199.8 0.0 1.4 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.23 KHN70477.1 - 0.015 15.4 1.5 0.022 14.8 0.1 1.9 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KHN70477.1 - 0.073 13.0 0.1 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Chitin_synth_2 PF03142.15 KHN70479.1 - 2.8e-202 673.0 12.2 1.9e-104 350.2 1.2 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KHN70479.1 - 2.3e-15 57.1 0.0 3.5e-13 50.0 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KHN70479.1 - 2.6e-15 56.9 1.0 2.6e-15 56.9 1.0 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KHN70479.1 - 7.5e-09 35.6 0.0 0.00069 19.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KHN70479.1 - 1.9e-06 27.5 0.0 2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Pkinase PF00069.25 KHN70481.1 - 1.1e-32 113.4 0.0 1.4e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70481.1 - 1.4e-15 57.3 0.3 5.2e-15 55.4 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KHN70481.1 - 0.0074 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KHN70481.1 - 0.01 15.2 0.6 0.019 14.4 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KHN70481.1 - 0.052 13.1 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KHN70481.1 - 0.08 12.5 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 RIO1 family DUF4270 PF14092.6 KHN70481.1 - 0.23 10.6 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) SGS PF05002.15 KHN70482.1 - 9.5e-19 67.3 2.0 1.5e-18 66.6 2.0 1.3 1 0 0 1 1 1 1 SGS domain CPSF_A PF03178.15 KHN70483.1 - 8.2e-11 41.8 5.3 3.6e-10 39.7 2.2 2.9 2 1 0 2 2 2 1 CPSF A subunit region Metallothio_6 PF05522.11 KHN70483.1 - 2.2 8.8 5.5 0.35 11.4 1.0 2.0 2 0 0 2 2 2 0 Metallothionein AAA PF00004.29 KHN70484.1 - 4.2e-58 195.5 0.3 2.5e-45 154.1 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KHN70484.1 - 5.1e-15 55.0 0.2 4.8e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KHN70484.1 - 8.1e-13 49.1 2.1 0.00031 21.2 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 KHN70484.1 - 3.3e-09 37.1 0.1 0.029 14.6 0.0 3.7 3 1 1 4 4 4 2 AAA domain AAA_14 PF13173.6 KHN70484.1 - 3.7e-09 36.7 0.0 0.00013 22.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 KHN70484.1 - 5.1e-08 33.0 0.1 0.0012 18.9 0.0 3.7 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KHN70484.1 - 1.3e-07 31.5 0.0 0.004 16.9 0.0 3.1 3 1 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KHN70484.1 - 6.6e-07 29.9 0.0 0.051 14.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 KHN70484.1 - 1.5e-06 28.4 0.0 0.044 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 KHN70484.1 - 5.1e-06 26.5 0.2 0.54 10.1 0.0 3.4 2 1 0 2 2 2 2 Bacterial dnaA protein Viral_helicase1 PF01443.18 KHN70484.1 - 7.4e-06 25.9 0.0 0.0035 17.1 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KHN70484.1 - 7.4e-06 26.5 0.3 0.0046 17.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KHN70484.1 - 1.5e-05 25.0 0.6 0.4 10.6 0.0 3.6 2 1 0 2 2 2 2 NACHT domain AAA_2 PF07724.14 KHN70484.1 - 2e-05 24.8 0.0 0.0024 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KHN70484.1 - 9.9e-05 22.3 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KHN70484.1 - 0.00012 22.3 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 KHN70484.1 - 0.00013 22.3 0.0 0.064 13.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 KHN70484.1 - 0.00021 20.7 0.6 0.39 10.0 0.0 3.5 4 1 0 4 4 4 1 KaiC NB-ARC PF00931.22 KHN70484.1 - 0.00022 20.5 0.1 2.1 7.5 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.13 KHN70484.1 - 0.00034 19.8 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Rad17 PF03215.15 KHN70484.1 - 0.00037 20.5 0.6 0.056 13.4 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 KHN70484.1 - 0.00037 20.3 0.1 0.45 10.2 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_17 PF13207.6 KHN70484.1 - 0.00069 20.0 0.1 1.8 9.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KHN70484.1 - 0.00085 19.1 0.1 0.86 9.3 0.0 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KHN70484.1 - 0.001 18.5 0.1 0.089 12.2 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KHN70484.1 - 0.0014 18.4 0.0 0.72 9.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 KHN70484.1 - 0.0016 17.9 0.0 2.4 7.5 0.0 3.9 3 1 1 4 4 4 1 Bacterial TniB protein Sigma54_activat PF00158.26 KHN70484.1 - 0.0018 18.0 0.0 4.5 6.9 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain CPT PF07931.12 KHN70484.1 - 0.002 18.0 0.0 0.89 9.4 0.0 2.9 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 KHN70484.1 - 0.002 17.7 0.0 2 8.0 0.0 3.1 2 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KHN70484.1 - 0.0024 17.2 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 KHN70484.1 - 0.0027 17.0 0.0 0.49 9.5 0.0 3.1 3 0 0 3 3 3 1 TIP49 P-loop domain RsgA_GTPase PF03193.16 KHN70484.1 - 0.0029 17.5 0.0 0.066 13.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KHN70484.1 - 0.0045 16.5 0.0 0.98 8.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 KHN70484.1 - 0.013 15.8 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KHN70484.1 - 0.015 15.2 2.8 0.26 11.1 0.0 3.4 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 KHN70484.1 - 0.015 14.5 0.0 0.44 9.7 0.0 2.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 KHN70484.1 - 0.018 15.4 0.1 4.6 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KHN70484.1 - 0.027 14.2 0.0 7.2 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRPRB PF09439.10 KHN70484.1 - 0.042 13.3 0.0 8.3 5.8 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 KHN70484.1 - 0.06 13.1 0.0 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KHN70484.1 - 0.099 12.5 2.1 7.4 6.4 0.0 3.3 3 1 1 4 4 4 0 NTPase AAA_11 PF13086.6 KHN70484.1 - 0.11 12.3 0.0 0.48 10.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain CLP1_N PF16573.5 KHN70485.1 - 4.8e-22 78.0 0.0 3.6e-21 75.2 0.0 2.2 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 KHN70485.1 - 5.6e-16 58.9 0.0 1.4e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KHN70485.1 - 1e-06 29.1 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 RHH_3 PF12651.7 KHN70485.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain tRNA-synt_1b PF00579.25 KHN70486.1 - 1.1e-56 192.3 0.0 1.3e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-RING_2 PF13639.6 KHN70487.1 - 5.9e-06 26.5 10.1 2.3e-05 24.6 10.1 2.1 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KHN70487.1 - 3.1e-05 23.9 7.1 3.1e-05 23.9 7.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KHN70487.1 - 0.00022 21.4 8.2 0.00022 21.4 8.2 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KHN70487.1 - 0.0051 16.7 5.6 0.016 15.1 5.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KHN70487.1 - 0.0072 16.4 6.5 0.02 15.0 6.5 1.9 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.6 KHN70487.1 - 0.13 12.1 8.3 0.51 10.2 8.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KHN70487.1 - 0.17 12.1 11.9 0.036 14.3 7.1 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 KHN70487.1 - 0.9 9.9 9.6 0.095 13.0 4.6 2.0 2 0 0 2 2 1 0 RING-like domain zf-RING_4 PF14570.6 KHN70487.1 - 0.97 9.3 6.6 2.5 8.0 6.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.22 KHN70487.1 - 1.3 9.0 6.4 0.63 10.0 3.8 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KHN70487.1 - 2.2 8.2 6.4 6.4 6.7 6.4 1.9 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 KHN70487.1 - 7.8 6.4 9.4 75 3.3 9.2 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PCI PF01399.27 KHN70489.1 - 1.2e-12 48.3 0.2 1.2e-12 48.3 0.2 3.0 5 0 0 5 5 5 1 PCI domain RPN5_C PF18098.1 KHN70489.1 - 1.6e-05 24.9 0.3 3.9e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain RPN7 PF10602.9 KHN70489.1 - 0.0011 18.7 1.8 0.0029 17.3 0.3 2.4 3 1 0 3 3 3 1 26S proteasome subunit RPN7 eIF3_subunit PF08597.10 KHN70490.1 - 0.028 14.4 0.0 0.033 14.1 0.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CdAMP_rec PF06153.11 KHN70490.1 - 0.15 12.3 0.4 1.6 9.0 0.0 1.9 1 1 1 2 2 2 0 Cyclic-di-AMP receptor RIO1 PF01163.22 KHN70491.1 - 8.6e-58 195.0 1.2 8.6e-58 195.0 1.2 2.4 3 0 0 3 3 3 1 RIO1 family APH PF01636.23 KHN70491.1 - 0.17 11.8 0.0 15 5.4 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_Rpb4 PF03874.16 KHN70492.1 - 5.2e-15 55.9 4.4 1.5e-14 54.4 4.4 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 POT1 PF02765.17 KHN70493.1 - 1.9e-08 34.2 0.2 5e-08 32.9 0.1 1.6 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 KHN70493.1 - 0.00087 19.2 2.0 0.037 14.0 0.4 3.3 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain POT1PC PF16686.5 KHN70493.1 - 0.025 14.4 0.5 2.3 8.1 0.1 2.9 1 1 2 3 3 3 0 ssDNA-binding domain of telomere protection protein PCNA_N PF00705.18 KHN70495.1 - 1.9e-20 72.8 0.6 3.2e-20 72.1 0.6 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KHN70495.1 - 6.6e-10 39.2 0.1 2.2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KHN70495.1 - 0.00074 19.0 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KHN70495.1 - 0.026 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DKCLD PF08068.12 KHN70496.1 - 7.5e-25 86.8 0.0 3.1e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KHN70496.1 - 2.6e-21 76.5 0.1 8.4e-18 65.2 0.1 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KHN70496.1 - 4e-20 71.7 0.4 6.7e-20 71.0 0.4 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KHN70496.1 - 6e-17 61.4 0.4 1.4e-16 60.2 0.4 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KHN70496.1 - 0.039 14.2 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain WD40 PF00400.32 KHN70497.1 - 9.5e-06 26.3 7.7 0.022 15.6 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70497.1 - 0.0073 16.6 0.0 0.048 14.0 0.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Arf PF00025.21 KHN70498.1 - 8.9e-21 74.1 0.1 1.1e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KHN70498.1 - 6.4e-06 25.6 0.1 0.013 14.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KHN70498.1 - 2.3e-05 24.6 0.2 5.9e-05 23.3 0.1 1.8 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KHN70498.1 - 0.00019 21.5 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KHN70498.1 - 0.00031 20.4 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KHN70498.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 KHN70498.1 - 0.021 14.7 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 NTPase Pox_A32 PF04665.12 KHN70498.1 - 0.041 13.3 0.1 0.082 12.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein DNA_pol_B PF00136.21 KHN70499.1 - 6.5e-96 321.8 1.4 8.6e-96 321.4 1.4 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 KHN70499.1 - 0.04 12.8 0.1 0.098 11.5 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral ANAPC10 PF03256.16 KHN70500.1 - 5.4e-31 107.7 0.2 6.1e-31 107.5 0.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Fe_hyd_lg_C PF02906.14 KHN70501.1 - 1.2e-33 116.8 0.1 1.6e-33 116.4 0.1 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain WBS_methylT PF12589.8 KHN70502.1 - 1.2e-09 38.7 7.4 1.2e-09 38.7 7.4 1.6 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KHN70502.1 - 1.3e-09 38.5 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KHN70502.1 - 1.1e-08 35.7 0.0 2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KHN70502.1 - 8.7e-06 25.7 0.0 2.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KHN70502.1 - 9.2e-06 25.1 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 KHN70502.1 - 7e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KHN70502.1 - 0.00011 22.9 0.0 0.00022 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KHN70502.1 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 KHN70502.1 - 0.00029 20.6 0.0 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 DNA methylase MetW PF07021.12 KHN70502.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KHN70502.1 - 0.22 10.9 0.2 0.41 10.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DEAD PF00270.29 KHN70503.1 - 2.4e-15 56.8 0.0 9.9e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KHN70503.1 - 9e-11 42.1 0.0 3.6e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KHN70503.1 - 4.1e-09 36.8 0.1 1.7e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain IP_trans PF02121.18 KHN70504.1 - 7e-45 153.5 2.5 8.7e-45 153.2 2.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein S4 PF01479.25 KHN70505.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KHN70505.1 - 0.0021 18.9 0.0 0.0035 18.2 0.0 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain LSM PF01423.22 KHN70506.1 - 1.9e-12 46.7 0.2 5.1e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 KHN70506.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Hfq protein Ribosomal_L21e PF01157.18 KHN70507.1 - 7.6e-37 125.2 6.1 1.2e-36 124.6 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF4192 PF13830.6 KHN70507.1 - 0.17 11.9 0.0 0.2 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Brr6_like_C_C PF10104.9 KHN70508.1 - 9e-35 119.4 0.1 1.4e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Toast_rack_N PF17115.5 KHN70508.1 - 0.098 13.0 1.0 1.5 9.2 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of toast_rack, DUF2154 SecE PF00584.20 KHN70509.1 - 1.1e-10 41.2 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4073 PF13285.6 KHN70510.1 - 0.002 17.8 1.0 0.0036 17.0 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4073) PTPA PF03095.15 KHN70510.1 - 0.0042 16.6 2.1 0.0059 16.1 2.1 1.3 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ham1p_like PF01725.16 KHN70511.1 - 5.4e-17 62.3 0.0 8.6e-17 61.7 0.0 1.4 1 1 0 1 1 1 1 Ham1 family 6PGD PF00393.19 KHN70512.1 - 2.6e-84 283.1 1.2 3.1e-84 282.8 1.2 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KHN70512.1 - 2.6e-40 138.2 0.1 6.1e-40 137.0 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KHN70512.1 - 1.4e-06 28.8 0.7 3.2e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KHN70512.1 - 7.9e-05 22.7 0.3 0.00046 20.3 0.1 2.4 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KHN70512.1 - 0.0033 17.3 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KHN70512.1 - 0.045 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KHN70512.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KHN70512.1 - 0.078 13.0 0.0 0.34 10.9 0.0 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PX PF00787.24 KHN70514.1 - 1.4e-12 47.6 0.1 1.7e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 PX domain Remorin_C PF03763.13 KHN70516.1 - 5.1 7.0 9.2 2.1 8.2 3.4 2.7 2 1 0 2 2 2 0 Remorin, C-terminal region NOG1_N PF17835.1 KHN70518.1 - 1.7e-46 158.1 0.3 3.3e-46 157.2 0.1 1.6 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 KHN70518.1 - 1.7e-19 69.4 0.1 3.3e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KHN70518.1 - 2.2e-17 63.2 0.0 1e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOGCT PF08155.11 KHN70518.1 - 1.6e-10 40.8 4.0 5.4e-10 39.1 4.0 2.0 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.18 KHN70518.1 - 9.3e-10 38.2 0.1 1.6e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KHN70518.1 - 0.0037 17.2 0.4 0.39 10.6 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KHN70518.1 - 0.0087 16.1 0.2 1.5 8.8 0.0 2.8 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 KHN70518.1 - 0.019 14.3 0.1 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family DUF5345 PF17280.2 KHN70520.1 - 0.038 14.0 0.1 0.038 14.0 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) CPBP PF02517.16 KHN70520.1 - 0.075 13.4 0.7 0.088 13.2 0.7 1.1 1 0 0 1 1 1 0 CPBP intramembrane metalloprotease UNC-93 PF05978.16 KHN70520.1 - 0.21 11.3 1.7 0.27 10.9 1.7 1.1 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 MCM PF00493.23 KHN70521.1 - 1.8e-99 331.4 0.3 2.6e-99 330.8 0.3 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KHN70521.1 - 4.4e-38 130.0 0.2 1.1e-37 128.7 0.2 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KHN70521.1 - 4.6e-23 81.4 2.5 9.8e-23 80.4 2.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KHN70521.1 - 7.4e-10 38.6 0.0 8.4e-07 28.6 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KHN70521.1 - 2.5e-07 30.8 0.0 8.6e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KHN70521.1 - 7.4e-06 25.9 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.6 KHN70521.1 - 2.1e-05 25.0 0.5 5.9e-05 23.6 0.5 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Sigma54_activat PF00158.26 KHN70521.1 - 0.00022 21.0 0.3 0.0018 18.0 0.1 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain MCM6_C PF18263.1 KHN70521.1 - 0.002 18.3 0.4 0.002 18.3 0.4 3.0 3 1 1 4 4 4 1 MCM6 C-terminal winged-helix domain AAA_7 PF12775.7 KHN70521.1 - 0.047 13.2 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Intein_splicing PF14890.6 KHN70521.1 - 0.33 10.9 1.3 5 7.1 0.2 3.0 2 1 2 4 4 4 0 Intein splicing domain Peptidase_C48 PF02902.19 KHN70523.1 - 1.9e-33 116.1 0.8 2.5e-33 115.7 0.8 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 KHN70523.1 - 0.00058 18.7 0.1 0.11 11.2 0.0 2.2 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase LupA PF18242.1 KHN70523.1 - 0.00087 19.0 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Legionella ubiquitin-specific protease A domain PEPCK_N PF17297.2 KHN70523.1 - 0.072 12.7 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase N-terminal domain EF-hand_14 PF17959.1 KHN70524.1 - 0.014 15.7 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 KHN70524.1 - 0.036 13.6 0.0 15 5.5 0.0 3.6 3 0 0 3 3 3 0 EF hand DUF296 PF03479.15 KHN70524.1 - 0.04 14.3 0.0 0.051 14.0 0.0 1.1 1 0 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain EF-hand_7 PF13499.6 KHN70524.1 - 0.053 14.0 0.9 1.6 9.2 0.9 2.8 1 1 0 1 1 1 0 EF-hand domain pair WD40_like PF17005.5 KHN70525.1 - 8.3e-97 324.1 17.8 9.4e-97 324.0 17.8 1.0 1 0 0 1 1 1 1 WD40-like domain Mcl1_mid PF12341.8 KHN70525.1 - 0.21 10.9 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region PQQ_3 PF13570.6 KHN70525.1 - 1.8 9.1 4.5 24 5.6 0.0 4.1 6 0 0 6 6 6 0 PQQ-like domain Aminotran_1_2 PF00155.21 KHN70526.1 - 1.8e-50 172.1 0.0 2.2e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KHN70526.1 - 0.0013 17.4 0.0 0.002 16.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KHN70526.1 - 0.008 15.5 0.1 0.055 12.8 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KHN70526.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 KHN70526.1 - 0.058 12.1 0.2 0.1 11.3 0.2 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain RhoGAP PF00620.27 KHN70528.1 - 1.6e-24 86.5 0.2 2.9e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 RhoGAP domain GCP_N_terminal PF17681.1 KHN70529.1 - 6e-17 62.2 0.0 1.3e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Yqai PF09466.10 KHN70529.1 - 0.067 13.5 0.2 0.34 11.3 0.2 2.3 1 0 0 1 1 1 0 Hypothetical protein Yqai GWT1 PF06423.12 KHN70530.1 - 1.3e-13 51.3 8.5 1.3e-13 51.3 8.5 2.9 2 1 0 2 2 2 1 GWT1 PseudoU_synth_2 PF00849.22 KHN70531.1 - 1.3e-27 96.9 0.0 2.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.18 KHN70531.1 - 2e-06 28.2 0.0 4.3e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Ribosomal_S6e PF01092.19 KHN70532.1 - 1.2e-49 167.4 1.0 2.1e-49 166.7 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e PTPS PF01242.19 KHN70532.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase BIR PF00653.21 KHN70533.1 - 1.3e-18 67.4 5.1 2.3e-16 60.2 2.8 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain PGI PF00342.19 KHN70534.1 - 4.6e-150 500.4 0.7 5.7e-150 500.1 0.7 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 KHN70536.1 - 2e-49 168.3 0.0 3.6e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KHN70536.1 - 3.8e-35 121.4 0.0 6.3e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 KHN70536.1 - 4.8e-06 26.7 0.4 1.4e-05 25.2 0.4 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 KHN70536.1 - 0.0077 15.0 0.3 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase LRR_6 PF13516.6 KHN70537.1 - 5.7e-07 29.1 5.0 5.5 7.3 0.0 7.6 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 KHN70537.1 - 2.7e-06 27.6 0.2 0.63 10.6 0.0 5.2 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KHN70537.1 - 0.00022 21.3 6.1 38 5.4 0.0 7.3 8 0 0 8 8 8 1 Leucine Rich Repeat zf-C2H2 PF00096.26 KHN70538.1 - 4e-05 23.8 6.6 0.0033 17.8 2.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KHN70538.1 - 0.01 16.2 1.7 0.064 13.7 1.7 2.5 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KHN70538.1 - 0.06 14.2 12.4 0.28 12.2 1.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1635 PF07795.11 KHN70538.1 - 5.6 6.8 9.9 0.24 11.2 3.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1635) Ribosomal_L1 PF00687.21 KHN70539.1 - 1.6e-19 70.5 2.0 2e-19 70.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Aa_trans PF01490.18 KHN70541.1 - 2.2e-55 188.0 35.9 2.8e-55 187.7 35.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KHN70541.1 - 4.9e-07 29.1 14.9 4.9e-07 29.1 14.9 1.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2238 PF09997.9 KHN70541.1 - 0.0076 16.1 3.4 0.0076 16.1 3.4 2.8 2 1 0 2 2 2 1 Predicted membrane protein (DUF2238) Peptidase_C65 PF10275.9 KHN70542.1 - 4.9e-20 72.0 2.6 1.5e-19 70.5 2.6 1.7 1 1 0 1 1 1 1 Peptidase C65 Otubain CPG4 PF15481.6 KHN70542.1 - 0.31 11.7 4.7 1.2 9.8 0.5 2.3 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 Fcf1 PF04900.12 KHN70543.1 - 2.4e-29 101.6 0.8 3.3e-29 101.2 0.2 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KHN70543.1 - 6.4e-11 42.6 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 PIN like domain GCV_T PF01571.21 KHN70543.1 - 0.047 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF2895 PF11444.8 KHN70543.1 - 0.3 10.4 1.7 1.3 8.3 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2895) WD40_like PF17005.5 KHN70544.1 - 7.3e-06 25.5 12.2 0.0074 15.6 0.3 3.5 1 1 3 4 4 4 3 WD40-like domain PQQ_3 PF13570.6 KHN70544.1 - 0.0016 18.9 0.3 0.023 15.2 0.0 2.8 3 0 0 3 3 3 1 PQQ-like domain DUF1093 PF06486.11 KHN70544.1 - 0.064 13.9 0.0 0.21 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1093) Peptidase_M61_N PF17899.1 KHN70544.1 - 0.16 12.1 0.2 0.56 10.3 0.1 1.9 2 0 0 2 2 2 0 Peptidase M61 N-terminal domain Coatomer_WDAD PF04053.14 KHN70544.1 - 0.25 10.4 5.7 0.9 8.5 4.5 2.0 1 1 1 2 2 2 0 Coatomer WD associated region FAT PF02259.23 KHN70545.1 - 2.1e-19 69.9 0.0 6.6e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 FAT domain V-ATPase_H_C PF11698.8 KHN70545.1 - 0.037 14.1 0.2 0.31 11.2 0.2 2.7 1 0 0 1 1 1 0 V-ATPase subunit H DUF4258 PF14076.6 KHN70545.1 - 0.074 13.4 0.1 0.65 10.4 0.1 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) TPR_1 PF00515.28 KHN70545.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KHN70545.1 - 0.14 12.4 0.0 0.51 10.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TAFII55_N PF04658.13 KHN70547.1 - 2.9e-23 82.3 4.2 2.9e-23 82.3 4.2 2.7 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF4368 PF14287.6 KHN70547.1 - 0.0043 17.3 2.2 0.016 15.5 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4368) XkdW PF09636.10 KHN70547.1 - 0.39 10.8 2.9 0.61 10.2 1.9 1.8 1 1 0 1 1 1 0 XkdW protein Bromo_TP_like PF17027.5 KHN70548.1 - 5.7e-39 133.0 1.0 5.7e-39 133.0 1.0 2.0 2 0 0 2 2 2 1 Histone-fold protein Bromo_TP PF07524.13 KHN70548.1 - 8.1e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIIB PF00382.19 KHN70549.1 - 1.1e-25 89.4 0.0 4.4e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KHN70549.1 - 1.2e-08 35.2 6.4 1.8e-08 34.6 4.3 2.3 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KHN70549.1 - 4.1e-07 29.4 1.2 1.1e-06 28.0 1.2 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_38 PF13936.6 KHN70549.1 - 0.0021 17.8 0.7 0.0059 16.3 0.7 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 KHN70549.1 - 0.0074 15.7 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.6 KHN70549.1 - 0.012 15.1 1.4 0.034 13.7 0.1 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 KHN70549.1 - 0.035 13.9 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_AsnC-type PF13404.6 KHN70549.1 - 0.04 13.8 4.1 0.084 12.7 0.1 2.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 KHN70549.1 - 0.065 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4 PF04545.16 KHN70549.1 - 0.099 12.2 0.4 0.24 10.9 0.4 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cyclin_N PF00134.23 KHN70549.1 - 0.1 12.4 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain HTH_11 PF08279.12 KHN70549.1 - 0.12 12.4 0.1 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 HTH domain Mga PF05043.13 KHN70549.1 - 0.12 13.0 0.0 0.31 11.7 0.0 1.7 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_30 PF13556.6 KHN70549.1 - 0.19 11.5 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Synaptobrevin PF00957.21 KHN70550.1 - 2.9e-11 43.0 0.1 3.2e-11 42.9 0.1 1.0 1 0 0 1 1 1 1 Synaptobrevin FadA PF09403.10 KHN70550.1 - 0.00027 21.4 1.6 0.00032 21.1 1.6 1.0 1 0 0 1 1 1 1 Adhesion protein FadA Xpo1 PF08389.12 KHN70551.1 - 0.093 12.8 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Exportin 1-like protein RL10P_insert PF17777.1 KHN70552.1 - 5.1e-07 29.6 0.0 8.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KHN70552.1 - 1.1e-05 25.5 1.4 1.7e-05 24.9 0.3 2.0 2 1 0 2 2 2 1 Ribosomal protein L10 DHH PF01368.20 KHN70554.1 - 2.2e-09 37.5 0.4 3.7e-09 36.7 0.4 1.4 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 KHN70554.1 - 1e-08 35.5 0.1 2.2e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 DHHA2 domain CBFD_NFYB_HMF PF00808.23 KHN70555.1 - 1.1e-16 60.8 0.2 2.4e-16 59.7 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KHN70555.1 - 1.6e-07 31.7 0.3 2.5e-07 31.1 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Metallophos PF00149.28 KHN70556.1 - 5.3e-28 98.9 0.9 7.2e-28 98.5 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KHN70556.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_2 PF07719.17 KHN70556.1 - 0.0042 17.1 0.3 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KHN70556.1 - 0.0049 17.1 0.2 0.4 11.0 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat SPO22 PF08631.10 KHN70556.1 - 0.096 12.2 1.0 1.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF1737 PF08410.10 KHN70557.1 - 0.053 13.4 0.0 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) MAP65_ASE1 PF03999.12 KHN70558.1 - 0.041 12.6 30.2 4 6.0 30.2 2.7 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) BDHCT PF08072.11 KHN70558.1 - 0.072 13.2 0.5 0.072 13.2 0.5 2.1 2 0 0 2 2 2 0 BDHCT (NUC031) domain DUF1796 PF08795.10 KHN70558.1 - 0.076 13.0 2.9 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) HBS1_N PF08938.10 KHN70558.1 - 0.086 13.2 3.0 8.9 6.7 1.2 3.3 2 1 0 2 2 2 0 HBS1 N-terminus MMR_HSR1_Xtn PF16897.5 KHN70560.1 - 1.6e-34 118.1 0.0 3.3e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KHN70560.1 - 1.2e-19 70.4 0.0 2.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KHN70560.1 - 1.7e-17 63.2 0.0 3.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KHN70560.1 - 7.6e-10 38.5 0.0 3.1e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KHN70560.1 - 0.002 17.2 0.1 0.0046 16.0 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KHN70560.1 - 0.065 13.3 0.3 12 6.0 0.0 2.7 1 1 1 2 2 2 0 Dynamin family Ploopntkinase3 PF18751.1 KHN70560.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 vATP-synt_E PF01991.18 KHN70561.1 - 9.3e-19 67.6 20.1 2.5e-17 62.9 20.1 2.3 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2621 PF11084.8 KHN70561.1 - 0.019 14.9 0.2 0.04 13.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2621) DUF3335 PF11814.8 KHN70561.1 - 0.044 13.2 1.3 0.14 11.6 0.0 2.2 1 1 2 3 3 3 0 Peptidase_C39 like family Porph_ging PF09697.10 KHN70561.1 - 7.1 7.3 6.3 9.9 6.8 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) Actin PF00022.19 KHN70562.1 - 5.5e-12 45.0 0.1 4.6e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Actin betaPIX_CC PF16523.5 KHN70562.1 - 2.1 8.2 5.7 7.9 6.4 0.3 2.7 2 0 0 2 2 2 0 betaPIX coiled coil Lactamase_B_6 PF16661.5 KHN70563.1 - 1.8e-29 102.6 0.0 4e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KHN70563.1 - 1.5e-05 25.3 1.1 2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta_lactamase3 PF17030.5 KHN70563.1 - 0.022 14.0 0.1 0.071 12.3 0.0 1.9 2 0 0 2 2 2 0 Putative beta-lactamase-like family EAV_GP5 PF15981.5 KHN70563.1 - 0.065 13.6 0.0 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 Envelope glycoprotein GP 5 of equine arteritis virus MAGE PF01454.19 KHN70564.1 - 5.6e-07 29.5 0.1 0.029 14.1 0.0 2.1 1 1 0 2 2 2 2 MAGE family TPR_12 PF13424.6 KHN70565.1 - 0.0026 18.0 0.0 0.0096 16.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KHN70565.1 - 0.0028 17.4 0.8 0.017 14.9 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CarD_CdnL_TRCF PF02559.16 KHN70565.1 - 0.0046 17.6 0.0 0.02 15.6 0.0 1.9 2 0 0 2 2 2 1 CarD-like/TRCF domain TPR_8 PF13181.6 KHN70565.1 - 0.019 15.1 0.4 0.11 12.8 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KHN70565.1 - 0.045 13.9 0.1 2.9 8.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KHN70565.1 - 0.05 13.1 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR eRF1_2 PF03464.15 KHN70566.1 - 1.4e-33 116.0 0.3 2.5e-33 115.2 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KHN70566.1 - 9.1e-30 103.4 0.1 2e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KHN70566.1 - 1.9e-13 50.5 0.0 4.2e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 KHN70566.1 - 5.6e-08 33.1 0.0 8.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KHN70566.1 - 1.1e-07 32.2 0.0 1.6e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Myb_DNA-binding PF00249.31 KHN70567.1 - 9.7e-13 48.1 0.1 2.9e-12 46.6 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KHN70567.1 - 5.4e-08 33.0 0.5 2e-07 31.1 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 KHN70567.1 - 3.9e-07 30.3 0.0 1.1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KHN70567.1 - 5.4e-05 23.1 0.5 0.00012 21.9 0.5 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Bap31 PF05529.12 KHN70568.1 - 2e-14 53.6 16.5 4e-13 49.4 12.9 2.6 2 1 0 2 2 2 1 Bap31/Bap29 transmembrane region DUF465 PF04325.13 KHN70568.1 - 0.0055 16.7 1.1 3.1 7.9 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF465) GAS PF13851.6 KHN70568.1 - 0.0074 15.7 10.3 0.0097 15.3 10.3 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KHN70568.1 - 0.058 12.5 5.6 0.077 12.1 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KHN70568.1 - 0.36 11.3 6.8 0.47 11.0 6.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region BRI3BP PF14965.6 KHN70568.1 - 1.5 8.3 10.3 2.5 7.6 0.8 2.3 2 1 0 2 2 2 0 Negative regulator of p53/TP53 DNA_pol_E_B PF04042.16 KHN70569.1 - 4.9e-07 29.3 0.4 3.6e-06 26.5 0.4 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PGK PF00162.19 KHN70570.1 - 2.4e-85 286.8 0.0 2.7e-85 286.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase AMP-binding PF00501.28 KHN70571.1 - 9e-76 255.1 0.0 1.1e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KHN70571.1 - 1.6e-18 66.3 1.9 3.4e-18 65.3 1.9 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KHN70571.1 - 1.2e-15 58.3 0.1 2.1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DNA_mis_repair PF01119.19 KHN70572.1 - 1.5e-23 82.7 0.2 3.1e-23 81.7 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Mlh1_C PF16413.5 KHN70572.1 - 1.1e-16 61.0 3.8 5.1e-09 35.9 0.1 3.3 2 1 1 3 3 3 3 DNA mismatch repair protein Mlh1 C-terminus HATPase_c_3 PF13589.6 KHN70572.1 - 3.5e-12 46.3 0.1 8.9e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KHN70572.1 - 9.4e-07 29.3 0.0 3.4e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cucumopine_C PF18631.1 KHN70572.1 - 0.0046 16.9 0.2 0.0095 15.9 0.2 1.4 1 0 0 1 1 1 1 Cucumopine synthase C-terminal helical bundle domain Proteasome PF00227.26 KHN70573.1 - 9.6e-25 87.2 0.2 1.3e-24 86.8 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit dUTPase PF00692.19 KHN70574.1 - 5.6e-11 42.2 0.0 1.4e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 dUTPase RNA_pol_L_2 PF13656.6 KHN70575.1 - 1.4e-15 56.8 0.3 1.6e-15 56.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NAD_Gly3P_dh_C PF07479.14 KHN70576.1 - 4e-38 130.9 0.1 6.4e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KHN70576.1 - 1.5e-36 125.7 0.0 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PMM PF03332.13 KHN70577.1 - 1.7e-91 305.9 4.2 2.1e-91 305.6 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KHN70577.1 - 1.5e-07 31.5 0.3 2.7e-07 30.6 0.3 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KHN70577.1 - 9.6e-05 22.0 0.0 0.0051 16.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Ribosomal_S3Ae PF01015.18 KHN70578.1 - 1.1e-62 211.2 7.2 1.6e-62 210.7 7.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family V_ATPase_I PF01496.19 KHN70578.1 - 0.0039 15.2 0.8 0.0059 14.6 0.8 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 KHN70578.1 - 0.071 11.8 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Flavodoxin_1 PF00258.25 KHN70579.1 - 2.9e-21 76.2 0.0 1.4e-19 70.7 0.0 2.5 1 1 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KHN70579.1 - 1.9e-09 37.4 0.1 2.8e-08 33.6 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KHN70579.1 - 0.0024 18.5 0.0 0.01 16.5 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2023 PF09633.10 KHN70580.1 - 0.013 15.7 0.5 0.05 13.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2023) RNA_helicase PF00910.22 KHN70580.1 - 0.016 15.6 0.5 0.021 15.2 0.5 1.2 1 0 0 1 1 1 0 RNA helicase zf-C2H2_3 PF13878.6 KHN70580.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Whib PF02467.16 KHN70580.1 - 0.09 13.4 0.2 0.18 12.4 0.1 1.6 2 0 0 2 2 2 0 Transcription factor WhiB CAF1 PF04857.20 KHN70580.1 - 0.16 11.1 0.9 3.4 6.8 0.1 2.1 1 1 1 2 2 2 0 CAF1 family ribonuclease WD40 PF00400.32 KHN70581.1 - 1.7e-16 60.3 12.6 9.3e-05 23.1 0.5 6.7 8 0 0 8 8 8 5 WD domain, G-beta repeat A1_Propeptide PF07966.12 KHN70581.1 - 0.026 14.4 0.4 0.052 13.4 0.4 1.5 1 0 0 1 1 1 0 A1 Propeptide Nup160 PF11715.8 KHN70581.1 - 0.081 11.5 1.0 4.5 5.8 0.1 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF4271 PF14093.6 KHN70582.1 - 0.0057 16.6 9.6 0.0057 16.6 9.6 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4271) AcrZ PF10766.9 KHN70582.1 - 0.23 11.0 0.2 0.23 11.0 0.2 2.7 3 0 0 3 3 3 0 Multidrug efflux pump-associated protein AcrZ zinc_ribbon_15 PF17032.5 KHN70583.1 - 4.3e-13 49.8 14.3 9.3e-13 48.7 14.3 1.6 1 1 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 KHN70583.1 - 0.0004 20.3 19.9 1.3 9.1 19.9 2.7 1 1 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 KHN70583.1 - 0.0031 16.9 14.1 0.052 13.0 0.6 3.9 3 1 0 3 3 3 2 zinc-ribbon domain DUF35_N PF12172.8 KHN70583.1 - 0.014 15.3 9.6 0.69 9.9 1.6 3.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PolC_DP2 PF03833.13 KHN70583.1 - 2.7 5.7 7.7 3.4 5.4 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 HypA PF01155.19 KHN70583.1 - 7.2 6.7 17.9 45 4.1 8.1 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WD40 PF00400.32 KHN70584.1 - 5.6e-15 55.5 7.7 0.015 16.2 0.2 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KHN70584.1 - 8e-08 32.5 0.2 0.29 11.4 0.0 5.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KHN70584.1 - 8.5e-05 22.8 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 KHN70584.1 - 0.0025 16.6 4.4 0.29 9.7 0.1 3.8 3 1 1 4 4 4 2 Nucleoporin Nup120/160 RPN1_RPN2_N PF17781.1 KHN70584.1 - 0.045 13.1 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain PPI_Ypi1 PF07491.11 KHN70585.1 - 3.1e-13 49.4 3.8 3.6e-13 49.1 3.8 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor SWIM PF04434.17 KHN70586.1 - 4.1e-05 23.2 1.5 0.00012 21.7 1.5 1.8 1 0 0 1 1 1 1 SWIM zinc finger BUD22 PF09073.10 KHN70587.1 - 0.93 8.8 7.3 1.3 8.3 7.3 1.3 1 1 0 1 1 1 0 BUD22 Insulin_TMD PF17870.1 KHN70588.1 - 0.016 15.2 1.4 0.016 15.2 1.4 2.9 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment HEPPP_synt_1 PF07307.11 KHN70588.1 - 0.022 14.4 4.1 0.45 10.1 0.4 2.5 3 0 0 3 3 3 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pyr_excise PF03013.14 KHN70590.1 - 0.097 12.7 0.8 0.21 11.5 0.1 1.8 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase DUF4355 PF14265.6 KHN70590.1 - 0.1 12.8 3.7 0.17 12.1 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF5091 PF17012.5 KHN70591.1 - 4.2e-62 208.8 0.4 4.7e-62 208.6 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5091) Arf PF00025.21 KHN70592.1 - 2.7e-37 127.9 0.0 3.3e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KHN70592.1 - 3.3e-11 43.0 0.1 5e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KHN70592.1 - 4.2e-11 42.7 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KHN70592.1 - 7e-11 42.4 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KHN70592.1 - 7.9e-11 42.0 0.1 1.2e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KHN70592.1 - 4.1e-10 39.3 0.5 1.7e-06 27.5 0.1 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KHN70592.1 - 4e-09 36.2 0.0 6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KHN70592.1 - 8.8e-08 31.9 1.3 3.9e-06 26.5 0.2 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KHN70592.1 - 2.6e-05 23.8 0.5 5.7e-05 22.7 0.5 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KHN70592.1 - 7.5e-05 22.7 0.8 0.33 10.8 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase cobW PF02492.19 KHN70592.1 - 0.00011 21.9 0.2 0.0093 15.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KHN70592.1 - 0.022 14.6 0.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 KHN70592.1 - 0.029 14.1 0.1 0.089 12.5 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NOG1 PF06858.14 KHN70592.1 - 0.1 12.4 0.3 0.41 10.5 0.3 2.1 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Thymidylate_kin PF02223.17 KHN70592.1 - 0.12 12.1 0.2 0.39 10.4 0.0 1.9 1 1 1 2 2 2 0 Thymidylate kinase AAA PF00004.29 KHN70592.1 - 0.15 12.5 0.1 0.81 10.1 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VRP1 PF03538.14 KHN70593.1 - 0.067 12.6 0.5 0.076 12.4 0.5 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein RIX1 PF08167.12 KHN70594.1 - 0.083 12.6 1.4 0.4 10.4 0.6 2.4 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis RICTOR_V PF14668.6 KHN70594.1 - 0.13 12.5 0.7 1.2 9.4 0.0 2.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Kinesin PF00225.23 KHN70595.1 - 1.2e-83 280.8 3.4 1.2e-83 280.8 3.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KHN70595.1 - 4.4e-19 68.9 0.7 4.4e-19 68.9 0.7 3.3 4 0 0 4 4 4 1 Microtubule binding WD40 PF00400.32 KHN70595.1 - 0.00018 22.2 6.1 0.091 13.7 0.3 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Cnn_1N PF07989.11 KHN70595.1 - 0.0016 18.5 8.9 0.0016 18.5 8.9 2.5 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 Herpes_BLRF2 PF05812.12 KHN70595.1 - 0.23 11.6 7.8 1.1 9.4 1.2 2.9 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DnaI_N PF07319.11 KHN70595.1 - 0.26 12.0 5.6 0.63 10.7 0.8 3.3 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus Com_YlbF PF06133.11 KHN70595.1 - 0.51 11.0 13.4 0.054 14.1 8.6 1.8 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Mto2_bdg PF12808.7 KHN70595.1 - 0.87 9.9 5.7 5.9 7.3 0.7 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region JIP_LZII PF16471.5 KHN70595.1 - 9.2 6.5 11.5 32 4.8 0.1 3.3 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF2615 PF11027.8 KHN70596.1 - 4.1 7.6 0.0 4.1 7.6 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2615) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Ordospora_colligata_OC4-ASM80326v1/GCA_000803265.1_ASM80326v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Ordospora_colligata_OC4-ASM80326v1/GCA_000803265.1_ASM80326v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Ordospora_colligata_OC4-ASM80326v1/GCA_000803265.1_ASM80326v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Ordospora_colligata_OC4-ASM80326v1/GCA_000803265.1_ASM80326v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:48:33 2019 # [ok]