# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2120 PF09893.4 KHN68777.1 - 1.1 9.2 11.3 2.9 7.8 0.8 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Peptidase_M1 PF01433.15 KHN68778.1 - 2.7e-82 276.9 0.1 4.8e-57 193.8 0.0 3.4 2 1 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 KHN68778.1 - 1e-15 57.8 0.0 3.3e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 Peptidase MA superfamily ERAP1_C PF11838.3 KHN68778.1 - 8.9e-05 21.8 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain DcuC PF03606.10 KHN68779.1 - 0.00096 17.4 1.4 0.0012 17.1 0.5 1.6 1 1 0 1 1 1 1 C4-dicarboxylate anaerobic carrier DUF788 PF05620.6 KHN68779.1 - 0.073 12.9 4.4 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF2976 PF11190.3 KHN68779.1 - 1.2 8.6 6.9 4.1 6.9 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) GAT PF03127.9 KHN68780.1 - 0.033 14.1 0.7 1.2 9.1 0.4 3.0 1 1 1 2 2 2 0 GAT domain AAA_23 PF13476.1 KHN68780.1 - 0.082 13.2 5.1 0.13 12.5 3.6 1.2 1 0 0 1 1 1 0 AAA domain Telomerase_RBD PF12009.3 KHN68781.1 - 0.0044 16.9 0.5 0.012 15.5 0.4 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain LcrG PF07216.7 KHN68781.1 - 0.15 12.0 3.1 16 5.6 0.0 3.9 2 1 2 4 4 4 0 LcrG protein FAD-SLDH PF12318.3 KHN68781.1 - 0.23 11.1 1.2 21 4.7 0.2 2.5 2 1 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4093 PF13331.1 KHN68781.1 - 8.8 6.6 14.1 1.1 9.5 3.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4093) LRR_4 PF12799.2 KHN68782.1 - 1.5e-18 65.9 13.6 2.8e-10 39.5 2.6 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KHN68782.1 - 1.1e-16 60.3 15.4 1.6e-08 34.1 0.6 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KHN68782.1 - 3.9e-12 44.4 12.7 0.001 18.7 0.1 6.3 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 KHN68782.1 - 2.6e-06 26.7 8.5 0.43 10.9 0.0 6.1 6 0 0 6 6 6 3 Leucine rich repeat PRD_Mga PF08270.6 KHN68782.1 - 0.0031 16.8 1.5 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 M protein trans-acting positive regulator (MGA) PRD domain LRR_6 PF13516.1 KHN68782.1 - 0.026 14.5 12.2 0.037 14.0 0.1 5.2 6 0 0 6 6 6 0 Leucine Rich repeat Thymidylat_synt PF00303.14 KHN68784.1 - 2.1e-48 164.6 0.1 2.3e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 Thymidylate synthase Flavi_NS4A PF01350.12 KHN68785.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Sld5 PF05916.6 KHN68785.1 - 0.094 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 GINS complex protein Pkinase PF00069.20 KHN68786.1 - 5e-51 173.3 0.1 6.7e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN68786.1 - 1.6e-23 83.1 0.0 2.5e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KHN68786.1 - 0.00023 20.5 0.2 0.0014 18.0 0.0 1.8 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 KHN68786.1 - 0.0004 20.2 0.0 0.00088 19.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KHN68786.1 - 0.01 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KHN68786.1 - 0.032 13.7 1.2 0.049 13.2 0.1 1.8 2 1 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.11 KHN68786.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family PAH PF02671.16 KHN68787.1 - 2.1e-23 81.6 6.2 6.8e-07 28.8 0.0 4.7 4 1 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KHN68787.1 - 7.4e-13 48.1 1.3 1.6e-12 47.0 0.3 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor She9_MDM33 PF05546.6 KHN68787.1 - 0.004 16.7 1.8 0.71 9.3 0.1 3.0 2 0 0 2 2 2 2 She9 / Mdm33 family DUF1160 PF06648.6 KHN68787.1 - 1.6 8.5 7.7 32 4.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1160) zf-SNAP50_C PF12251.3 KHN68788.1 - 4.2e-07 29.5 3.4 1.6e-06 27.6 2.4 2.0 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF2860 PF11059.3 KHN68788.1 - 0.13 11.2 0.2 0.26 10.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2860) ubiquitin PF00240.18 KHN68789.1 - 0.038 13.4 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family MAT1 PF06391.8 KHN68790.1 - 7.7e-15 55.0 1.6 9.8e-15 54.6 1.1 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KHN68790.1 - 1.9e-06 27.4 5.8 1.9e-06 27.4 4.0 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KHN68790.1 - 4.4e-06 26.2 7.0 4.4e-06 26.2 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KHN68790.1 - 0.00011 22.1 8.7 0.00011 22.1 6.0 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN68790.1 - 0.00019 21.0 10.0 0.0014 18.2 6.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KHN68790.1 - 0.0015 18.2 8.1 0.0036 17.0 5.6 1.7 1 1 0 1 1 1 1 Ring finger domain DNA_ligase_ZBD PF03119.11 KHN68790.1 - 0.0035 17.0 1.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent DNA ligase C4 zinc finger domain zf-RING_4 PF14570.1 KHN68790.1 - 0.059 12.9 15.0 0.29 10.7 8.4 2.8 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 KHN68790.1 - 0.14 11.9 4.7 12 5.7 1.7 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 KHN68790.1 - 0.2 11.5 8.9 0.54 10.1 6.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.2 KHN68790.1 - 0.48 10.2 6.9 1.9 8.3 4.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 KHN68790.1 - 2.4 7.9 10.0 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 KHN68790.1 - 2.9 7.9 8.6 2.3 8.2 0.9 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Ribosomal_S21e PF01249.13 KHN68791.1 - 9e-12 44.7 0.1 9.6e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e TIM PF00121.13 KHN68792.1 - 8.4e-73 244.4 0.0 9.4e-73 244.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CRM1_C PF08767.6 KHN68793.1 - 3.8e-50 170.5 16.7 3.8e-50 170.5 11.6 3.5 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KHN68793.1 - 1.5e-30 106.1 4.2 1.5e-30 106.1 2.9 3.5 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KHN68793.1 - 1.1e-07 31.5 0.5 5.6e-07 29.3 0.4 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain CoaE PF01121.15 KHN68794.1 - 1.4e-17 63.6 1.4 2.2e-09 36.9 0.1 2.1 1 1 1 2 2 2 2 Dephospho-CoA kinase AAA_28 PF13521.1 KHN68794.1 - 3e-06 27.2 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN68794.1 - 1.2e-05 26.1 0.1 1.5e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KHN68794.1 - 0.00023 21.4 0.1 0.00037 20.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KHN68794.1 - 0.0063 15.6 0.2 0.011 14.8 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KHN68794.1 - 0.011 15.4 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KHN68794.1 - 0.016 15.3 0.1 0.026 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KHN68794.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KHN68794.1 - 0.022 14.6 0.2 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KHN68794.1 - 0.062 13.5 0.3 0.15 12.3 0.2 1.7 1 1 0 1 1 1 0 ABC transporter cobW PF02492.14 KHN68794.1 - 0.078 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KHN68794.1 - 0.082 12.4 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 KHN68794.1 - 0.11 11.1 0.3 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 KHN68794.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.1 KHN68794.1 - 1.5 9.1 3.6 2.5 8.3 2.5 1.8 1 1 0 1 1 1 0 AAA domain P53_tetramer PF07710.6 KHN68795.1 - 2.2 7.4 7.1 0.31 10.1 0.1 2.8 3 0 0 3 3 3 0 P53 tetramerisation motif ABC_tran PF00005.22 KHN68797.1 - 3.8e-26 92.0 0.0 7.2e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KHN68797.1 - 7.5e-06 25.5 1.6 1.4e-05 24.6 1.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KHN68797.1 - 0.0034 16.6 0.8 0.52 9.4 0.0 2.7 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KHN68797.1 - 0.082 12.4 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KHN68797.1 - 0.086 13.1 0.6 0.41 10.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 KHN68797.1 - 0.12 12.2 10.1 2.7 7.9 4.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KHN68797.1 - 0.2 10.0 4.4 4.6 5.5 0.2 3.0 3 0 0 3 3 3 0 AAA domain DUF1461 PF07314.6 KHN68797.1 - 0.37 10.5 6.8 0.028 14.1 0.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) PIN_4 PF13638.1 KHN68798.1 - 4.3e-13 49.5 2.0 7.2e-13 48.7 1.4 1.4 1 0 0 1 1 1 1 PIN domain zf-CHY PF05495.7 KHN68799.1 - 9.5e-15 54.5 22.8 9.5e-15 54.5 15.8 4.3 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 KHN68799.1 - 6.7e-10 38.6 9.6 6.7e-10 38.6 6.7 4.9 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KHN68799.1 - 4.4e-08 32.6 8.1 4.4e-08 32.6 5.6 5.7 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_6 PF14599.1 KHN68799.1 - 2.1e-07 30.6 1.1 2.1e-07 30.6 0.8 4.5 2 1 3 5 5 5 1 Zinc-ribbon zf-C3HC4_2 PF13923.1 KHN68799.1 - 3.9e-07 29.9 9.2 3.9e-07 29.9 6.4 5.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN68799.1 - 3.2e-06 26.7 9.6 3.2e-06 26.7 6.7 6.6 2 1 3 5 5 5 1 zinc-RING finger domain Rtf2 PF04641.7 KHN68799.1 - 0.0058 15.8 2.2 0.0058 15.8 1.5 1.9 1 1 0 2 2 2 1 Rtf2 RING-finger GDI PF00996.13 KHN68800.1 - 9.4e-11 40.6 3.2 9.5e-05 20.8 0.1 2.5 1 1 0 2 2 2 2 GDP dissociation inhibitor CagZ PF09053.5 KHN68800.1 - 0.021 14.1 0.5 0.048 12.9 0.1 1.7 2 0 0 2 2 2 0 CagZ Med31 PF05669.7 KHN68801.1 - 3.9e-31 106.8 3.0 4.2e-31 106.7 2.1 1.0 1 0 0 1 1 1 1 SOH1 RNA_pol_Rpb2_6 PF00562.23 KHN68802.1 - 7.1e-114 380.5 0.4 7.1e-114 380.5 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KHN68802.1 - 8.7e-46 155.4 1.3 8.7e-46 155.4 0.9 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 KHN68802.1 - 5.9e-28 96.9 0.1 2.6e-27 94.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KHN68802.1 - 1.8e-20 73.1 0.5 3.6e-20 72.2 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KHN68802.1 - 3e-20 71.7 0.3 8.3e-20 70.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KHN68802.1 - 4e-15 55.3 1.3 1.1e-14 53.9 0.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KHN68802.1 - 4.1e-13 49.0 0.7 9.7e-13 47.8 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ubiquitin PF00240.18 KHN68803.1 - 8.2e-14 50.7 0.2 1.3e-13 50.1 0.2 1.3 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KHN68803.1 - 2e-05 24.1 0.2 2.6e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KHN68803.1 - 0.017 15.3 0.1 0.019 15.1 0.1 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KHN68803.1 - 0.027 14.3 0.1 0.041 13.7 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 KHN68803.1 - 0.06 13.0 0.0 0.064 12.9 0.0 1.0 1 0 0 1 1 1 0 Telomere stability and silencing Sec6 PF06046.8 KHN68804.1 - 1.2e-91 307.5 13.5 1.6e-91 307.1 9.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 PMC2NT PF08066.7 KHN68804.1 - 0.018 15.3 4.1 2.4 8.5 0.0 3.7 4 0 0 4 4 4 0 PMC2NT (NUC016) domain Erv26 PF04148.8 KHN68805.1 - 9.1e-14 51.3 13.2 1.1e-12 47.8 9.2 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1440 PF07274.7 KHN68805.1 - 0.16 11.9 3.1 0.13 12.2 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) PalH PF08733.5 KHN68805.1 - 0.3 9.8 6.4 0.36 9.6 4.4 1.2 1 0 0 1 1 1 0 PalH/RIM21 SAC3_GANP PF03399.11 KHN68806.1 - 0.012 15.2 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KHN68806.1 - 0.022 14.5 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Sel1 PF08238.7 KHN68808.1 - 3.7e-84 275.3 25.0 1.2e-09 38.5 0.6 13.2 13 0 0 13 13 13 13 Sel1 repeat TPR_6 PF13174.1 KHN68808.1 - 1.1e-05 25.5 4.0 0.62 10.6 0.0 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_11 PF13414.1 KHN68808.1 - 0.00062 19.3 27.2 0.16 11.6 0.1 7.6 4 2 3 8 8 8 3 TPR repeat Apc3 PF12895.2 KHN68808.1 - 1.4 9.1 12.6 75 3.5 1.0 6.5 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KHN68808.1 - 1.8 8.9 19.1 9 6.7 0.0 7.8 5 2 2 7 7 7 0 Tetratricopeptide repeat RRM_1 PF00076.17 KHN68809.1 - 7e-05 22.3 0.1 0.00014 21.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN68809.1 - 0.0013 18.5 0.2 0.0027 17.5 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN68809.1 - 0.09 12.7 0.3 0.59 10.1 0.1 2.1 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PI3_PI4_kinase PF00454.22 KHN68810.1 - 5.9e-32 111.0 0.0 1.7e-30 106.2 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KHN68810.1 - 2.3e-06 26.9 1.6 7.3e-06 25.2 0.7 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pescadillo_N PF06732.6 KHN68811.1 - 1.5e-21 76.9 6.6 2.8e-21 76.0 4.6 1.4 1 0 0 1 1 1 1 Pescadillo N-terminus GIDA PF01134.17 KHN68811.1 - 0.055 12.3 0.1 0.094 11.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Arb2 PF09757.4 KHN68811.1 - 0.072 12.5 0.2 9.2 5.6 0.0 2.3 2 0 0 2 2 2 0 Arb2 domain Kinesin PF00225.18 KHN68812.1 - 6.1e-76 255.2 3.9 8.9e-76 254.7 2.7 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_2 PF07647.12 KHN68812.1 - 0.00037 20.2 0.2 0.00098 18.9 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KHN68812.1 - 0.044 13.9 0.2 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CTP_synth_N PF06418.9 KHN68813.1 - 4.3e-48 163.7 0.3 6e-48 163.3 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KHN68813.1 - 1.1e-42 145.6 0.0 2.1e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KHN68813.1 - 5.5e-06 25.9 0.3 3.6e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KHN68813.1 - 0.026 13.9 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1699 PF08004.6 KHN68814.1 - 0.013 15.0 0.3 0.013 15.0 0.2 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) DUF1090 PF06476.7 KHN68814.1 - 0.071 12.7 3.2 0.19 11.4 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) CASP_C PF08172.7 KHN68814.1 - 0.09 11.7 2.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 CASP C terminal Exonuc_VII_S PF02609.11 KHN68814.1 - 3.4 7.5 8.8 3.6 7.4 1.4 3.3 3 0 0 3 3 3 0 Exonuclease VII small subunit RRM_1 PF00076.17 KHN68815.1 - 2.1e-08 33.6 0.0 1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN68815.1 - 0.002 18.0 0.0 0.01 15.7 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN68815.1 - 0.045 13.6 0.0 0.17 11.7 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BolA PF01722.13 KHN68816.1 - 4e-18 65.1 0.5 5.1e-18 64.7 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein DNA_pol3_a_NII PF11490.3 KHN68816.1 - 0.01 15.4 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Acetyltransf_1 PF00583.19 KHN68816.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Polysacc_deac_1 PF01522.16 KHN68817.1 - 0.041 13.5 0.0 0.075 12.6 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide deacetylase Cyclin_N PF00134.18 KHN68818.1 - 1e-08 34.8 0.7 5.1e-08 32.5 0.1 2.0 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 KHN68818.1 - 0.11 12.8 1.3 0.13 12.6 0.9 1.4 1 1 0 1 1 1 0 Cyclin tRNA-synt_1b PF00579.20 KHN68820.1 - 6.8e-23 81.2 0.0 2.5e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HSP70 PF00012.15 KHN68821.1 - 1.3e-215 716.8 4.3 1.5e-215 716.6 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KHN68821.1 - 5.1e-19 68.0 2.3 3.8e-18 65.1 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KHN68821.1 - 3.4e-07 30.1 1.8 0.014 15.2 0.0 3.7 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KHN68821.1 - 0.0023 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain ArfGap PF01412.13 KHN68822.1 - 4.4e-30 103.8 1.6 4.4e-30 103.8 1.1 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf JAB PF01398.16 KHN68824.1 - 3.1e-32 110.7 0.1 4.8e-32 110.0 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KHN68824.1 - 2.3e-15 56.6 0.0 1e-14 54.5 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KHN68824.1 - 9.6e-08 31.5 0.0 1.4e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 KHN68824.1 - 0.028 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) NuA4 PF09340.5 KHN68826.1 - 3.2e-07 29.8 1.7 3.9e-07 29.6 1.2 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 BBS2_C PF14782.1 KHN68826.1 - 0.094 11.2 0.5 0.1 11.1 0.3 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal RNA_pol_L_2 PF13656.1 KHN68827.1 - 9.5e-15 53.7 0.0 1.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CPSF_A PF03178.10 KHN68829.1 - 4.1e-53 180.5 1.5 6.9e-53 179.8 0.1 1.9 2 0 0 2 2 2 1 CPSF A subunit region CDP-OH_P_transf PF01066.16 KHN68830.1 - 1.1e-12 48.1 18.7 1.2e-12 47.9 9.7 3.1 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase LSM PF01423.17 KHN68832.1 - 7.4e-09 35.0 0.2 8.9e-09 34.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF150 PF02576.12 KHN68832.1 - 0.032 13.8 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised BCR, YhbC family COG0779 Motile_Sperm PF00635.21 KHN68833.1 - 5.7e-21 74.2 0.2 8.3e-21 73.6 0.2 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Metallophos PF00149.23 KHN68834.1 - 1.3e-47 161.7 0.5 1.8e-47 161.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase eIF2A PF08662.6 KHN68835.1 - 5.5e-26 91.4 0.1 3.3e-25 88.9 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KHN68835.1 - 0.0051 15.6 0.1 0.31 9.7 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Apc3 PF12895.2 KHN68836.1 - 9.1e-07 28.9 4.4 0.00022 21.3 1.2 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KHN68836.1 - 0.00065 19.4 7.3 0.17 11.8 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KHN68836.1 - 0.0075 16.5 0.3 5.1 7.5 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat HTH_38 PF13936.1 KHN68836.1 - 0.025 14.1 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_1 PF00515.23 KHN68836.1 - 0.04 13.5 6.9 0.42 10.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KHN68836.1 - 0.3 11.0 2.7 3.6 7.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KHN68836.1 - 0.53 10.2 10.7 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 KHN68836.1 - 0.81 9.3 6.3 9.7 5.9 0.2 3.0 2 1 1 3 3 3 0 TPR repeat NTP_transferase PF00483.18 KHN68837.1 - 9.8e-47 159.3 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KHN68837.1 - 2.5e-12 47.1 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KHN68837.1 - 1e-06 27.9 9.5 0.0041 16.5 1.6 3.1 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Glycos_transf_2 PF00535.21 KHN68837.1 - 0.028 14.0 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 CTP_transf_3 PF02348.14 KHN68837.1 - 0.036 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Fucokinase PF07959.7 KHN68837.1 - 0.05 12.1 0.4 0.099 11.1 0.3 1.5 1 0 0 1 1 1 0 L-fucokinase IspD PF01128.14 KHN68837.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pam16 PF03656.8 KHN68838.1 - 8.3e-08 32.0 0.1 1.3e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 Pam16 Ribosomal_S10 PF00338.17 KHN68840.1 - 1.1e-08 34.7 0.6 1.4e-08 34.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Sec63 PF02889.11 KHN68840.1 - 0.0011 18.2 0.2 0.0012 18.1 0.2 1.1 1 0 0 1 1 1 1 Sec63 Brl domain Mit_KHE1 PF10173.4 KHN68840.1 - 0.0024 17.7 0.4 0.0027 17.5 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related CBFD_NFYB_HMF PF00808.18 KHN68841.1 - 5.7e-12 45.5 0.3 9.2e-12 44.8 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Met_synt_B12 PF02965.12 KHN68841.1 - 0.0097 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B2 PF11473.3 KHN68841.1 - 0.045 13.3 0.2 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 RNA binding protein B2 Histone PF00125.19 KHN68841.1 - 0.055 13.5 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TBCA PF02970.11 KHN68841.1 - 0.18 11.8 4.0 0.13 12.4 0.8 2.1 2 0 0 2 2 2 0 Tubulin binding cofactor A HAUS2 PF15003.1 KHN68842.1 - 0.036 13.1 2.2 0.039 13.0 1.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Opi1 PF08618.5 KHN68842.1 - 0.064 12.1 4.0 0.077 11.9 2.8 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 KH_1 PF00013.24 KHN68843.1 - 7.3e-06 25.5 3.2 7.3e-06 25.5 2.2 2.1 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KHN68843.1 - 0.0053 16.3 2.3 0.0077 15.8 0.4 2.1 2 0 0 2 2 2 1 KH domain KH_4 PF13083.1 KHN68843.1 - 0.021 14.4 0.3 0.063 12.9 0.1 1.9 2 0 0 2 2 2 0 KH domain EppA_BapA PF07268.6 KHN68843.1 - 0.026 14.1 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) XPG_I PF00867.13 KHN68844.1 - 5.3e-20 71.2 0.3 7e-19 67.6 0.1 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KHN68844.1 - 5.8e-16 58.6 0.0 1.4e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KHN68844.1 - 0.0019 18.3 0.0 0.0052 16.9 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_lambd_f PF10391.4 KHN68844.1 - 0.027 14.0 0.0 0.076 12.5 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF445 PF04286.7 KHN68844.1 - 0.07 12.6 0.1 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3906 PF13046.1 KHN68844.1 - 0.12 11.9 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3906) Exo_endo_phos PF03372.18 KHN68845.1 - 3.3e-19 69.7 0.0 4.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KHN68845.1 - 5.7e-16 57.7 10.1 6.1e-09 35.2 1.6 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KHN68845.1 - 6.9e-11 41.7 8.9 7.1e-07 28.8 2.4 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KHN68845.1 - 3.9e-10 38.3 5.6 0.14 12.2 0.0 5.7 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 KHN68845.1 - 2e-07 30.3 6.2 0.042 13.9 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 KHN68845.1 - 0.00011 21.7 3.3 5.8 7.5 0.1 4.8 4 0 0 4 4 4 2 Leucine rich repeat Exo_endo_phos_2 PF14529.1 KHN68845.1 - 0.011 15.3 0.0 0.07 12.7 0.0 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Ribosomal_S7e PF01251.13 KHN68846.1 - 0.081 12.3 0.5 0.14 11.5 0.3 1.6 1 1 0 1 1 1 0 Ribosomal protein S7e Sec23_trunk PF04811.10 KHN68847.1 - 3.7e-36 124.7 0.0 7.6e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KHN68847.1 - 7.6e-21 73.4 0.6 1.4e-20 72.6 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KHN68847.1 - 2e-14 53.8 0.1 4.4e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KHN68847.1 - 1.5e-12 46.8 5.6 4.3e-12 45.3 3.9 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KHN68847.1 - 0.00025 20.6 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Gelsolin repeat MCM PF00493.18 KHN68848.1 - 7.6e-97 324.0 0.0 1e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 KHN68848.1 - 1.7e-07 31.0 0.1 4.5e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KHN68848.1 - 3.4e-06 26.3 0.1 0.00027 20.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KHN68848.1 - 0.046 12.7 0.1 0.14 11.2 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KHN68848.1 - 0.047 13.0 0.1 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KHN68848.1 - 0.058 12.8 0.0 7.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Nif11 PF07862.6 KHN68848.1 - 0.076 12.9 0.1 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Nitrogen fixation protein of unknown function AAA_3 PF07726.6 KHN68848.1 - 0.11 12.1 0.0 0.9 9.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L11 PF00298.14 KHN68848.1 - 0.23 11.6 1.2 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Ribosomal_S8e PF01201.17 KHN68849.1 - 2.2e-33 115.1 1.3 3.6e-33 114.5 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Bud13 PF09736.4 KHN68849.1 - 0.6 10.3 9.4 0.99 9.6 6.5 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Rad51 PF08423.6 KHN68850.1 - 1.2e-135 450.4 0.1 1.5e-135 450.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.1 KHN68850.1 - 8.4e-10 38.6 0.4 1.6e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.1 KHN68850.1 - 1.4e-08 34.4 0.0 2.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 KHN68850.1 - 2.7e-08 33.2 0.1 3.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KHN68850.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 KHN68850.1 - 0.012 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KHN68850.1 - 0.04 13.4 0.0 0.089 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain TFIID_30kDa PF03540.8 KHN68851.1 - 7.2e-20 70.5 0.0 1.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 KHN68851.1 - 0.018 14.7 0.1 0.11 12.2 0.0 2.2 1 1 2 3 3 3 0 Bromodomain associated AAA PF00004.24 KHN68852.1 - 6e-27 94.4 0.2 4.3e-26 91.6 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN68852.1 - 3.1e-05 23.6 0.2 0.00069 19.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KHN68852.1 - 4e-05 23.7 0.0 0.00012 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KHN68852.1 - 8.5e-05 22.5 0.1 8.5e-05 22.5 0.1 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.10 KHN68852.1 - 0.00044 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_17 PF13207.1 KHN68852.1 - 0.00044 21.0 0.1 0.0029 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KHN68852.1 - 0.0018 17.7 0.0 0.0041 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KHN68852.1 - 0.0031 16.9 0.0 0.055 12.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN68852.1 - 0.0031 17.3 0.2 0.011 15.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KHN68852.1 - 0.0042 16.9 2.0 0.013 15.2 0.6 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KHN68852.1 - 0.0062 15.5 0.0 0.0093 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KHN68852.1 - 0.009 15.6 0.2 0.009 15.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KHN68852.1 - 0.012 15.3 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain TrwB_AAD_bind PF10412.4 KHN68852.1 - 0.016 13.8 1.1 0.02 13.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 KHN68852.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KHN68852.1 - 0.024 14.8 0.1 0.14 12.3 0.0 2.4 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KHN68852.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KHN68852.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1183 PF06682.7 KHN68852.1 - 0.061 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) T2SE PF00437.15 KHN68852.1 - 0.062 12.1 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.6 KHN68852.1 - 0.071 12.7 0.1 0.68 9.5 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KHN68852.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 KHN68852.1 - 0.18 10.9 5.8 2.7 7.1 0.2 3.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF1517 PF07466.6 KHN68852.1 - 0.37 9.7 3.0 0.61 9.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) HA2 PF04408.18 KHN68853.1 - 6.9e-17 61.3 0.0 1.7e-16 60.0 0.0 1.8 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KHN68853.1 - 1.7e-12 47.1 0.1 3.7e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KHN68853.1 - 3.8e-12 46.0 0.9 1.3e-11 44.3 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN68853.1 - 1.4e-10 40.9 0.0 3.2e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KHN68853.1 - 4.9e-06 26.7 0.1 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KHN68853.1 - 0.0004 20.2 0.4 0.019 14.8 0.3 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KHN68853.1 - 0.0014 17.6 0.0 0.0028 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KHN68853.1 - 0.0016 18.3 2.9 0.0062 16.4 1.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KHN68853.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KHN68853.1 - 0.0047 16.3 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 KHN68853.1 - 0.012 14.7 4.3 0.015 14.4 0.6 2.6 2 1 0 2 2 2 0 KaiC DUF2075 PF09848.4 KHN68853.1 - 0.013 14.4 1.0 0.021 13.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 KHN68853.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain UPF0079 PF02367.12 KHN68853.1 - 0.033 13.7 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 KHN68853.1 - 0.058 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Phage_G PF02306.10 KHN68853.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Major spike protein (G protein) NACHT PF05729.7 KHN68853.1 - 0.099 12.3 0.2 3 7.4 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 KHN68853.1 - 0.57 9.8 8.4 0.021 14.5 0.7 2.3 3 0 0 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 KHN68853.1 - 0.66 9.5 6.9 0.92 9.0 0.1 3.2 3 1 1 4 4 4 0 AAA domain CTP_transf_2 PF01467.21 KHN68854.1 - 1.8e-29 102.8 0.1 1.3e-15 57.8 0.0 2.9 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 KHN68854.1 - 0.00026 20.6 0.4 1.2 8.7 0.0 3.3 2 1 0 2 2 2 2 FAD synthetase tRNA-synt_1g PF09334.6 KHN68855.1 - 4e-133 443.8 0.0 4.8e-133 443.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KHN68855.1 - 8.7e-08 30.6 0.9 3.1e-06 25.5 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) PMC2NT PF08066.7 KHN68855.1 - 0.038 14.3 0.1 0.081 13.2 0.1 1.5 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DZR PF12773.2 KHN68855.1 - 1.6 8.6 9.0 29 4.5 6.2 2.6 1 1 0 1 1 1 0 Double zinc ribbon HEAT_2 PF13646.1 KHN68856.1 - 1.4e-07 31.6 0.0 0.15 12.3 0.0 5.8 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 KHN68856.1 - 0.00036 20.3 5.4 36 4.8 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat Utp14 PF04615.8 KHN68857.1 - 8.2e-36 123.4 31.8 6e-33 114.0 5.7 2.4 1 1 1 2 2 2 2 Utp14 protein Ribosomal_S8 PF00410.14 KHN68857.1 - 0.017 14.9 3.4 0.042 13.6 2.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S8 P63C PF10546.4 KHN68857.1 - 0.76 9.7 4.4 8.5 6.3 1.6 3.3 2 1 1 3 3 3 0 P63C domain EIF_2_alpha PF07541.7 KHN68859.1 - 5.8e-17 61.4 1.0 4.5e-16 58.5 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KHN68859.1 - 9.8e-10 38.3 0.2 3.4e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 S1 RNA binding domain Cut8_C PF08559.5 KHN68859.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Cut8 six-helix bundle Ribosomal_L7Ae PF01248.21 KHN68861.1 - 3e-11 42.6 0.1 4.5e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KHN68861.1 - 0.0031 17.3 0.0 0.0033 17.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Pkinase PF00069.20 KHN68863.1 - 4.9e-71 238.9 0.1 5.9e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN68863.1 - 1.9e-39 135.3 0.2 2.5e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN68863.1 - 6.2e-06 25.3 0.0 9.1e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KHN68863.1 - 2.6e-05 23.3 0.2 4.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KHN68863.1 - 0.001 18.4 0.2 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KHN68863.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DCP1 PF06058.8 KHN68864.1 - 3.8e-22 78.6 0.0 4.7e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family Synaptobrevin PF00957.16 KHN68865.1 - 4.8e-06 26.0 1.4 4.8e-06 26.0 0.9 1.8 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 KHN68865.1 - 0.002 17.6 0.1 0.0035 16.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec20 PF03908.8 KHN68865.1 - 0.0038 16.9 0.9 0.034 13.8 0.2 2.2 2 0 0 2 2 2 1 Sec20 Flagellar_rod PF05149.7 KHN68865.1 - 0.033 13.3 0.1 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein MCPsignal PF00015.16 KHN68865.1 - 0.094 12.2 0.5 0.91 9.0 0.1 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C2H2 PF00096.21 KHN68866.1 - 3.5e-05 23.8 3.6 0.026 14.8 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KHN68866.1 - 9.8e-05 22.4 1.3 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KHN68866.1 - 0.0074 16.3 2.2 0.013 15.6 1.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KHN68866.1 - 0.038 13.8 6.0 1 9.3 0.1 3.0 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KHN68866.1 - 0.064 13.4 3.2 2 8.6 0.2 3.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding GLTP PF08718.6 KHN68866.1 - 0.11 12.5 0.7 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) Mesd PF10185.4 KHN68866.1 - 0.12 12.0 2.2 6.9 6.3 0.2 2.1 2 0 0 2 2 2 0 Chaperone for wingless signalling and trafficking of LDL receptor C1_2 PF03107.11 KHN68866.1 - 0.14 12.2 3.2 10 6.3 0.3 2.6 2 0 0 2 2 2 0 C1 domain DUF2256 PF10013.4 KHN68866.1 - 0.17 11.6 2.2 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Rad50_zn_hook PF04423.9 KHN68866.1 - 0.19 11.2 0.1 0.19 11.2 0.1 2.7 2 1 1 3 3 3 0 Rad50 zinc hook motif RRN7 PF11781.3 KHN68866.1 - 0.33 10.4 3.0 7.6 6.1 0.5 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_2 PF13465.1 KHN68866.1 - 0.41 11.0 7.3 1.1 9.7 0.3 2.8 2 1 0 2 2 2 0 Zinc-finger double domain Mut7-C PF01927.11 KHN68866.1 - 0.71 9.8 5.5 0.39 10.6 1.7 1.8 1 1 1 2 2 2 0 Mut7-C RNAse domain HypA PF01155.14 KHN68866.1 - 0.74 9.5 5.2 1.4 8.6 3.6 1.6 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 KHN68866.1 - 1.5 8.5 8.5 4.1 7.1 5.9 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like XPA_N PF01286.13 KHN68866.1 - 5.2 6.8 7.1 10 5.8 0.3 2.7 3 0 0 3 3 3 0 XPA protein N-terminal zf-RING_2 PF13639.1 KHN68867.1 - 2.7e-13 49.4 6.1 4.6e-13 48.7 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KHN68867.1 - 5.5e-12 45.5 6.0 8.1e-12 44.9 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KHN68867.1 - 5.2e-10 38.8 4.9 9.4e-10 37.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN68867.1 - 5.7e-10 38.7 4.7 8.5e-10 38.1 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN68867.1 - 7.1e-09 35.2 5.3 1.2e-08 34.5 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KHN68867.1 - 1.1e-08 35.0 7.9 2.7e-08 33.7 5.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KHN68867.1 - 2.1e-05 24.2 6.0 4.8e-05 23.1 4.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KHN68867.1 - 0.0009 18.7 3.3 0.0017 17.8 2.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KHN68867.1 - 0.0011 18.6 2.2 0.0029 17.2 1.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Di19 PF05605.7 KHN68867.1 - 0.0017 18.4 3.1 0.2 11.7 0.4 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.1 KHN68867.1 - 0.0024 17.7 6.5 0.012 15.4 4.0 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 KHN68867.1 - 0.018 14.8 5.4 0.059 13.2 3.7 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 KHN68867.1 - 0.036 14.0 9.2 3.3 7.7 6.4 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 KHN68867.1 - 0.095 12.4 1.5 0.16 11.7 1.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KHN68867.1 - 0.096 12.2 2.0 0.14 11.7 1.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 KHN68867.1 - 0.15 12.0 7.5 0.48 10.5 4.6 2.0 1 1 1 2 2 2 0 RING-variant domain Rtf2 PF04641.7 KHN68867.1 - 0.22 10.7 1.9 0.25 10.5 1.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING-like PF08746.6 KHN68867.1 - 0.23 11.4 7.7 0.41 10.6 4.7 1.9 1 1 1 2 2 2 0 RING-like domain zf-RING_3 PF14369.1 KHN68867.1 - 0.27 11.2 4.4 1.3 9.1 0.4 2.4 2 0 0 2 2 2 0 zinc-finger PHD PF00628.24 KHN68867.1 - 0.34 10.6 8.0 0.63 9.7 4.9 1.9 1 1 1 2 2 2 0 PHD-finger UPF0547 PF10571.4 KHN68867.1 - 0.67 9.6 0.2 0.67 9.6 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Prok-RING_1 PF14446.1 KHN68867.1 - 6.7 6.5 8.2 4.3 7.1 1.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 LsmAD PF06741.8 KHN68869.1 - 1.5e-14 53.8 1.1 3.6e-14 52.6 0.8 1.7 1 0 0 1 1 1 1 LsmAD domain AAA PF00004.24 KHN68870.1 - 1.1e-39 135.6 0.0 1.9e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KHN68870.1 - 3.6e-06 26.7 0.1 1.2e-05 25.0 0.1 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 KHN68870.1 - 3.5e-05 23.9 0.5 0.0023 18.0 0.4 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KHN68870.1 - 7.5e-05 21.8 0.0 0.00017 20.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KHN68870.1 - 0.00017 21.3 0.1 0.0011 18.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KHN68870.1 - 0.0017 18.2 0.0 0.0075 16.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KHN68870.1 - 0.0023 17.3 0.5 1.4 8.2 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KHN68870.1 - 0.0023 17.9 0.1 0.011 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 KHN68870.1 - 0.0065 16.0 0.0 0.016 14.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KHN68870.1 - 0.0073 15.4 0.1 0.016 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KHN68870.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 KHN68870.1 - 0.013 15.2 0.1 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 KHN68870.1 - 0.038 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 KHN68870.1 - 0.066 12.3 0.5 8.3 5.4 0.2 2.3 1 1 1 2 2 2 0 KaiC AAA_14 PF13173.1 KHN68870.1 - 0.07 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KHN68870.1 - 0.11 13.2 0.2 0.37 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KHN68870.1 - 0.14 12.3 0.0 0.89 9.7 0.0 2.3 2 1 0 2 2 2 0 RNA helicase PTR2 PF00854.16 KHN68872.1 - 3e-62 210.5 15.2 1.4e-46 159.0 4.1 2.2 1 1 1 2 2 2 2 POT family DUF3179 PF11376.3 KHN68872.1 - 0.13 11.3 0.2 0.24 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) BCCT PF02028.12 KHN68873.1 - 0.052 11.7 5.3 0.024 12.9 2.3 1.5 1 1 1 2 2 2 0 BCCT family transporter adh_short PF00106.20 KHN68874.1 - 1.3e-16 60.9 0.0 2.3e-15 56.9 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KHN68874.1 - 3.3e-09 36.8 0.0 6.7e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KHN68874.1 - 6.7e-06 25.8 0.0 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KHN68874.1 - 8.8e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KHN68874.1 - 0.00019 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KHN68874.1 - 0.0013 17.8 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KHN68874.1 - 0.0019 17.9 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KHN68874.1 - 0.0023 17.9 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Pyr_redox PF00070.22 KHN68874.1 - 0.041 14.2 0.0 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Helicase_RecD PF05127.9 KHN68874.1 - 0.052 13.1 0.1 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Helicase ADH_zinc_N PF00107.21 KHN68874.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2855 PF11017.3 KHN68874.1 - 0.093 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) F420_oxidored PF03807.12 KHN68874.1 - 0.12 12.8 0.1 0.31 11.4 0.0 1.7 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sod_Fe_C PF02777.13 KHN68875.1 - 3.9e-34 116.6 2.7 4.5e-34 116.4 0.2 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KHN68875.1 - 3.1e-26 91.4 0.6 6.2e-26 90.4 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Erf4 PF10256.4 KHN68876.1 - 1e-06 28.5 0.0 1.6e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family tRNA-synt_1 PF00133.17 KHN68877.1 - 7.5e-197 655.0 0.0 1.1e-167 558.6 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KHN68877.1 - 7.3e-24 84.2 0.1 3e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KHN68877.1 - 1.3e-16 60.3 0.1 4e-06 25.7 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KHN68877.1 - 0.0059 15.7 0.1 0.094 11.8 0.0 2.8 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain Phage_GP20 PF06810.6 KHN68878.1 - 0.0004 19.8 25.1 0.51 9.7 5.9 4.0 2 1 1 3 3 3 3 Phage minor structural protein GP20 bZIP_1 PF00170.16 KHN68878.1 - 0.027 14.4 2.0 0.027 14.4 1.4 5.1 4 2 3 7 7 7 0 bZIP transcription factor Lebercilin PF15619.1 KHN68878.1 - 0.12 11.7 26.4 1.2 8.5 12.9 3.3 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.7 KHN68878.1 - 0.55 9.9 31.6 0.56 9.9 9.0 3.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KHN68878.1 - 0.68 8.5 29.5 0.11 11.1 9.9 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 KHN68878.1 - 0.96 8.5 10.3 3.2 6.8 3.4 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 KHN68878.1 - 1.2 8.6 22.8 0.049 13.1 2.5 4.8 3 1 1 4 4 4 0 Septum formation initiator Pox_A_type_inc PF04508.7 KHN68878.1 - 1.9 8.4 16.1 24 5.0 0.2 6.1 5 1 0 5 5 5 0 Viral A-type inclusion protein repeat DUF848 PF05852.6 KHN68878.1 - 2.6 7.8 22.4 0.035 13.9 2.9 3.6 2 2 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2203 PF09969.4 KHN68878.1 - 3.8 7.7 17.8 0.12 12.6 0.7 3.7 2 2 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Sec20 PF03908.8 KHN68878.1 - 9.6 5.9 13.1 2.2 8.0 0.8 3.2 2 1 1 3 3 3 0 Sec20 GTP_EFTU PF00009.22 KHN68879.1 - 1.8e-30 105.7 0.2 2.7e-30 105.2 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KHN68879.1 - 8.8e-08 31.9 0.1 5.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 KHN68879.1 - 0.0042 17.0 0.1 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RING_2 PF13639.1 KHN68880.1 - 5.3e-09 35.7 11.3 1.1e-08 34.8 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KHN68880.1 - 1.1e-07 31.7 11.8 2.3e-07 30.7 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KHN68880.1 - 2.7e-07 30.1 4.6 6.8e-07 28.8 3.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN68880.1 - 3e-07 30.0 7.6 6e-07 29.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN68880.1 - 2.1e-06 27.3 8.2 2.1e-06 27.3 5.7 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KHN68880.1 - 1.2e-05 24.9 10.4 5.6e-05 22.7 1.3 2.4 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KHN68880.1 - 9.3e-05 22.2 9.6 0.00023 20.9 6.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 KHN68880.1 - 0.0041 16.9 4.5 0.0072 16.1 3.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 KHN68880.1 - 0.022 14.5 5.1 0.5 10.1 4.3 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KHN68880.1 - 0.11 12.6 7.5 0.3 11.2 5.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DiS_P_DiS PF06750.8 KHN68880.1 - 0.44 10.3 8.0 0.042 13.6 1.9 1.9 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain CCER1 PF15482.1 KHN68880.1 - 0.63 9.6 4.5 0.83 9.2 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Prok-RING_4 PF14447.1 KHN68880.1 - 0.98 9.0 7.8 2.6 7.6 5.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ORMDL PF04061.9 KHN68881.1 - 1.4e-26 92.6 6.1 1.6e-26 92.4 4.2 1.0 1 0 0 1 1 1 1 ORMDL family TPR_1 PF00515.23 KHN68882.1 - 1.3e-20 72.0 17.4 0.0013 18.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KHN68882.1 - 1.4e-19 68.3 12.3 0.014 15.3 0.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 KHN68882.1 - 7.2e-19 67.2 7.7 1.8e-07 30.7 0.5 5.8 4 2 1 5 5 5 3 TPR repeat TPR_7 PF13176.1 KHN68882.1 - 1.9e-13 49.1 0.4 0.0058 16.3 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KHN68882.1 - 6.1e-13 48.5 7.4 4.9e-05 23.1 0.1 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 KHN68882.1 - 1.3e-12 46.4 18.1 0.036 13.8 0.0 8.1 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KHN68882.1 - 6.5e-09 36.2 0.0 0.0038 17.8 0.0 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KHN68882.1 - 2.3e-08 33.9 0.0 3.2 8.6 0.0 6.3 4 1 3 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KHN68882.1 - 5.2e-08 32.9 11.2 0.00051 20.1 2.5 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KHN68882.1 - 6.7e-08 32.7 0.0 0.028 14.7 0.0 6.0 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KHN68882.1 - 1.2e-06 28.6 2.3 6.3 7.4 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 KHN68882.1 - 0.00045 20.1 6.5 0.29 11.4 0.0 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KHN68882.1 - 0.027 14.3 7.3 4.4 7.2 0.0 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 KHN68882.1 - 0.085 12.9 0.0 1.5 9.0 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KHN68882.1 - 0.099 12.5 0.0 3 7.7 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KHN68882.1 - 0.12 12.2 2.7 32 4.6 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.27 KHN68883.1 - 2.4e-10 39.9 0.2 0.0032 17.2 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat UTP15_C PF09384.5 KHN68883.1 - 4.4e-09 36.2 1.4 7.7e-09 35.4 1.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal Pup PF05639.6 KHN68883.1 - 0.032 14.7 1.3 0.09 13.2 0.9 1.7 1 0 0 1 1 1 0 Pup-like protein PQQ_3 PF13570.1 KHN68883.1 - 0.056 13.7 5.9 0.36 11.1 0.6 3.2 4 0 0 4 4 4 0 PQQ-like domain DivIC PF04977.10 KHN68883.1 - 0.073 12.5 3.6 0.23 10.9 2.5 1.9 1 1 0 1 1 1 0 Septum formation initiator ParA PF10609.4 KHN68884.1 - 2.5e-27 94.5 0.3 6.8e-27 93.1 0.2 1.8 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KHN68884.1 - 9.7e-19 67.5 0.1 1.4e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KHN68884.1 - 2.1e-06 27.7 0.0 5.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KHN68884.1 - 2.4e-06 26.8 0.8 0.00013 21.0 0.2 2.5 1 1 1 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KHN68884.1 - 0.00047 19.3 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ MobB PF03205.9 KHN68884.1 - 0.0013 18.4 0.1 0.0057 16.3 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 KHN68884.1 - 0.0017 17.6 0.2 0.0081 15.3 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.1 KHN68884.1 - 0.0099 16.6 0.0 0.026 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KHN68884.1 - 0.013 15.8 0.1 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KHN68884.1 - 0.026 13.7 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 KHN68884.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 KHN68884.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.17 KHN68884.1 - 0.057 12.8 0.6 1.4 8.3 0.0 2.6 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 KHN68884.1 - 0.065 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 KHN68884.1 - 0.067 12.8 0.1 0.067 12.8 0.1 1.9 3 0 0 3 3 2 0 NTPase OrfB_Zn_ribbon PF07282.6 KHN68884.1 - 0.086 12.5 1.1 0.23 11.1 0.7 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RRN7 PF11781.3 KHN68884.1 - 0.47 9.9 2.7 8 6.0 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 GCC2_GCC3 PF07699.8 KHN68884.1 - 3.4 7.3 7.7 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 DUF1451 PF07295.6 KHN68884.1 - 5.7 6.7 6.2 1.2 8.9 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) ABC_tran PF00005.22 KHN68885.1 - 1e-29 103.5 0.0 1.8e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KHN68885.1 - 6.7e-19 68.3 12.5 1e-18 67.7 8.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KHN68885.1 - 1.2e-13 51.6 0.7 8.1e-13 48.9 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KHN68885.1 - 8.8e-07 28.3 0.7 0.003 16.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KHN68885.1 - 7.2e-06 25.3 5.2 6.2e-05 22.3 1.4 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KHN68885.1 - 5.7e-05 22.5 0.1 0.00017 21.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KHN68885.1 - 0.00021 19.9 0.4 0.085 11.3 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KHN68885.1 - 0.0023 18.2 0.0 0.0085 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KHN68885.1 - 0.0023 17.9 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KHN68885.1 - 0.0025 17.2 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KHN68885.1 - 0.0033 18.2 0.0 0.0083 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KHN68885.1 - 0.005 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KHN68885.1 - 0.0051 16.3 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KHN68885.1 - 0.0067 16.5 0.4 0.087 12.9 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KHN68885.1 - 0.0091 16.3 0.1 0.019 15.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KHN68885.1 - 0.02 15.0 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KHN68885.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 KHN68885.1 - 0.024 14.4 0.1 0.063 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KHN68885.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 KHN68885.1 - 0.03 14.2 0.1 0.08 12.9 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase MobB PF03205.9 KHN68885.1 - 0.031 13.9 0.1 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KHN68885.1 - 0.036 13.6 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KHN68885.1 - 0.04 13.3 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain DUF815 PF05673.8 KHN68885.1 - 0.045 12.6 0.1 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 KHN68885.1 - 0.064 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 KHN68885.1 - 0.066 12.9 0.1 8.4 6.0 0.0 2.4 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 KHN68885.1 - 0.072 12.9 0.7 0.14 11.9 0.5 1.5 1 0 0 1 1 1 0 Dynamin family DUF258 PF03193.11 KHN68885.1 - 0.093 11.9 0.1 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1469 PF07332.6 KHN68885.1 - 0.48 10.1 3.2 0.25 11.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Spindle_Spc25 PF08234.7 KHN68888.1 - 3.3e-10 39.8 0.1 7.2e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF812 PF05667.6 KHN68888.1 - 0.005 15.4 3.3 0.0057 15.2 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3450 PF11932.3 KHN68888.1 - 0.019 14.2 1.9 0.032 13.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4045 PF13254.1 KHN68888.1 - 0.021 14.1 0.8 0.026 13.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Macoilin PF09726.4 KHN68888.1 - 3 6.0 10.9 4 5.6 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein XendoU PF09412.5 KHN68889.1 - 0.01 14.8 1.3 0.021 13.8 0.9 1.5 1 0 0 1 1 1 0 Endoribonuclease XendoU Bromo_TP PF07524.8 KHN68890.1 - 0.00077 19.1 0.2 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated TAF8_C PF10406.4 KHN68890.1 - 0.0011 18.9 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term MutL_C PF08676.6 KHN68891.1 - 1.5e-25 89.4 0.0 2.5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KHN68891.1 - 1.9e-07 30.5 0.0 4.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KHN68891.1 - 2.3e-07 30.5 0.0 6.3e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KHN68891.1 - 1.1e-06 28.2 0.0 2.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TIP49 PF06068.8 KHN68892.1 - 8.5e-133 442.9 9.9 2.1e-132 441.6 6.9 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KHN68892.1 - 7.7e-07 29.3 0.7 0.00018 21.7 0.2 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KHN68892.1 - 2e-05 24.7 0.0 0.067 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KHN68892.1 - 4.1e-05 23.6 0.0 0.00037 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 KHN68892.1 - 6.7e-05 22.4 0.2 0.059 12.8 0.2 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.7 KHN68892.1 - 0.00076 18.5 0.7 0.92 8.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KHN68892.1 - 0.0031 16.7 1.7 0.091 11.9 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KHN68892.1 - 0.004 16.7 0.2 0.95 9.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain DBI_PRT PF02277.12 KHN68892.1 - 0.0041 16.2 0.5 0.0065 15.6 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyltransferase AAA_19 PF13245.1 KHN68892.1 - 0.0059 16.3 0.3 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 KHN68892.1 - 0.0065 16.1 0.8 0.016 14.8 0.2 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 KHN68892.1 - 0.0086 15.8 0.7 1.9 8.2 0.1 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KHN68892.1 - 0.012 14.5 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 KHN68892.1 - 0.03 14.2 0.2 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1870 PF08965.5 KHN68892.1 - 0.032 13.8 0.1 0.063 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) AAA_17 PF13207.1 KHN68892.1 - 0.07 13.9 1.1 0.15 12.9 0.4 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 KHN68892.1 - 0.071 13.4 0.2 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain HEM4 PF02602.10 KHN68892.1 - 0.083 12.1 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD RHH_1 PF01402.16 KHN68892.1 - 0.091 12.6 0.9 0.25 11.2 0.1 2.3 2 0 0 2 2 1 0 Ribbon-helix-helix protein, copG family ATP-synt_ab PF00006.20 KHN68893.1 - 6.7e-112 372.2 0.0 9.6e-112 371.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KHN68893.1 - 1.1e-17 64.4 0.1 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KHN68893.1 - 2.6e-11 43.5 1.1 2.6e-11 43.5 0.7 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Pkinase PF00069.20 KHN68894.1 - 4.5e-62 209.5 0.0 5.4e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN68894.1 - 4.4e-31 107.8 0.0 6.2e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN68894.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KHN68894.1 - 0.003 16.9 0.1 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KHN68894.1 - 0.033 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2630 PF10944.3 KHN68895.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Pyr_redox_2 PF07992.9 KHN68896.1 - 1.8e-11 44.2 0.0 9.5e-10 38.6 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KHN68896.1 - 1.4e-10 41.5 0.1 2.3e-05 24.5 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KHN68896.1 - 9.5e-09 33.9 0.2 0.0026 16.0 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KHN68896.1 - 3.3e-07 30.2 0.1 7.7e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KHN68896.1 - 2.7e-06 26.6 0.1 9.8e-06 24.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KHN68896.1 - 4.4e-06 25.8 0.1 0.00017 20.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KHN68896.1 - 3.4e-05 22.4 0.1 0.00014 20.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 KHN68896.1 - 0.00012 21.3 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KHN68896.1 - 0.00013 20.9 0.1 0.00026 19.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KHN68896.1 - 0.00084 19.6 2.1 0.12 12.7 0.1 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KHN68896.1 - 0.0016 18.2 0.0 0.081 12.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KHN68896.1 - 0.0022 17.1 0.0 0.0042 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KHN68896.1 - 0.0035 17.5 0.3 0.43 10.8 0.0 3.0 2 1 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 KHN68896.1 - 0.0067 15.3 0.0 0.015 14.1 0.0 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KHN68896.1 - 0.0087 15.1 0.1 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 KHN68896.1 - 0.026 14.6 0.2 29 4.7 0.0 3.8 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase Erf4 PF10256.4 KHN68896.1 - 0.076 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family TRAPP PF04051.11 KHN68897.1 - 3.5e-15 55.8 0.0 4.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Fork_head PF00250.13 KHN68898.1 - 5.1e-33 112.9 0.4 8.6e-33 112.2 0.3 1.4 1 0 0 1 1 1 1 Fork head domain ABC_tran PF00005.22 KHN68899.1 - 5.1e-19 68.9 0.0 5.1e-19 68.9 0.0 3.5 3 1 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 KHN68899.1 - 1.2e-05 25.4 0.0 1.2e-05 25.4 0.0 7.5 3 3 3 6 6 6 1 AAA domain AAA_25 PF13481.1 KHN68899.1 - 0.0041 16.5 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KHN68899.1 - 0.016 14.6 0.1 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IF4E PF01652.13 KHN68900.1 - 2.4e-23 82.4 0.5 2.6e-23 82.3 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Hormone_6 PF00236.13 KHN68900.1 - 0.11 12.3 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein hormone dsDNA_bind PF01984.15 KHN68901.1 - 0.00067 19.6 0.2 0.0007 19.5 0.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF3819 PF12842.2 KHN68902.1 - 4.1e-20 71.9 0.5 4.1e-20 71.9 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Ribosomal_L15e PF00827.12 KHN68903.1 - 3.9e-78 261.3 8.6 4.4e-78 261.1 6.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Fip1 PF05182.8 KHN68904.1 - 1.8e-24 84.7 2.5 2.8e-24 84.1 1.7 1.3 1 0 0 1 1 1 1 Fip1 motif RNA_POL_M_15KD PF02150.11 KHN68905.1 - 3.2e-10 39.5 3.6 3.2e-10 39.5 2.5 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 KHN68905.1 - 1.9e-05 24.1 12.0 2.4e-05 23.8 1.7 3.2 3 1 0 3 3 3 2 Transcription factor S-II (TFIIS) DZR PF12773.2 KHN68905.1 - 0.026 14.3 1.8 0.026 14.3 1.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KHN68905.1 - 0.11 11.7 4.7 5.4 6.3 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 KHN68905.1 - 1.3 9.0 12.5 0.45 10.5 1.5 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain GFA PF04828.9 KHN68905.1 - 1.6 8.6 8.3 4 7.4 0.0 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KHN68905.1 - 3.2 7.5 12.5 2.5 7.9 1.6 3.1 2 2 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) HypA PF01155.14 KHN68905.1 - 3.8 7.2 8.7 1.3e+02 2.2 6.0 2.2 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TPP1 PF10341.4 KHN68906.1 - 1.1e-11 44.5 0.1 5.5e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Shelterin complex subunit, TPP1/ACD AAA_2 PF07724.9 KHN68907.1 - 2.6e-42 144.6 0.9 2.7e-39 134.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KHN68907.1 - 4.6e-26 91.5 0.2 2.3e-13 50.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN68907.1 - 3.9e-18 65.5 1.2 1e-10 41.4 0.0 3.5 4 1 0 4 4 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 KHN68907.1 - 2.9e-15 55.9 0.5 3.1e-14 52.6 0.1 3.0 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KHN68907.1 - 3.1e-13 50.1 0.1 7.4e-05 22.8 0.0 4.4 2 2 1 4 4 4 2 AAA ATPase domain IstB_IS21 PF01695.12 KHN68907.1 - 2.1e-09 37.0 0.0 0.00016 21.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.1 KHN68907.1 - 5e-09 36.3 0.5 0.0014 18.7 0.0 3.9 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 KHN68907.1 - 6.7e-09 35.4 0.2 3.4e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 KHN68907.1 - 2.4e-08 33.6 0.3 0.013 15.1 0.2 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_14 PF13173.1 KHN68907.1 - 6.7e-08 32.4 0.0 0.00087 19.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 KHN68907.1 - 1.7e-07 30.5 0.6 0.059 12.5 0.1 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KHN68907.1 - 3e-06 26.9 0.1 0.025 14.2 0.0 2.9 3 0 0 3 3 2 2 NACHT domain Clp_N PF02861.15 KHN68907.1 - 3.1e-06 26.9 0.0 2.7e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Clp amino terminal domain AAA_17 PF13207.1 KHN68907.1 - 4e-06 27.6 5.6 0.003 18.3 0.0 4.2 4 1 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 KHN68907.1 - 5.5e-06 26.2 7.5 0.0036 17.0 0.1 4.0 4 1 1 5 5 4 2 Archaeal ATPase Zeta_toxin PF06414.7 KHN68907.1 - 1.3e-05 24.4 1.5 0.028 13.4 0.0 3.6 4 0 0 4 4 4 2 Zeta toxin RuvB_N PF05496.7 KHN68907.1 - 1.3e-05 24.3 2.4 0.035 13.1 0.0 3.6 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 KHN68907.1 - 1.4e-05 24.7 2.5 0.073 12.5 0.0 3.2 2 1 1 3 3 3 2 AAA-like domain AAA_25 PF13481.1 KHN68907.1 - 2.4e-05 23.8 1.6 0.12 11.8 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KHN68907.1 - 3.6e-05 24.0 5.7 0.056 13.7 0.0 4.5 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 KHN68907.1 - 8e-05 22.7 0.0 0.42 10.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase DUF258 PF03193.11 KHN68907.1 - 8.6e-05 21.7 0.1 0.038 13.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 KHN68907.1 - 9.6e-05 22.7 1.6 0.27 11.5 0.0 3.7 3 1 0 3 3 3 1 ABC transporter NTPase_1 PF03266.10 KHN68907.1 - 0.00012 21.8 1.0 0.42 10.2 0.1 3.6 2 1 1 3 3 3 1 NTPase UPF0079 PF02367.12 KHN68907.1 - 0.00012 21.7 0.1 0.67 9.5 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KHN68907.1 - 0.00012 20.9 7.7 0.12 11.1 0.1 3.6 3 1 1 4 4 4 2 TIP49 C-terminus AAA_23 PF13476.1 KHN68907.1 - 0.00019 21.8 6.7 0.25 11.6 0.0 3.6 3 1 0 3 3 3 1 AAA domain T2SE PF00437.15 KHN68907.1 - 0.00027 19.9 0.0 0.082 11.8 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 KHN68907.1 - 0.00038 19.4 0.2 0.24 10.2 0.1 2.8 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.8 KHN68907.1 - 0.00062 18.7 0.0 0.26 10.1 0.0 2.9 3 0 0 3 3 2 1 Protein of unknown function (DUF815) CbiA PF01656.18 KHN68907.1 - 0.00083 18.8 0.1 0.31 10.4 0.0 2.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 KHN68907.1 - 0.00084 18.8 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.1 KHN68907.1 - 0.00097 18.7 0.1 0.2 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KHN68907.1 - 0.0014 18.5 0.7 0.18 11.7 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KHN68907.1 - 0.0014 18.1 0.0 0.054 12.9 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 KHN68907.1 - 0.0015 18.0 0.0 0.47 9.9 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KHN68907.1 - 0.0016 18.3 4.0 0.54 10.0 0.0 3.6 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DUF87 PF01935.12 KHN68907.1 - 0.0016 18.3 0.1 0.0016 18.3 0.0 3.6 3 1 1 4 4 2 1 Domain of unknown function DUF87 Torsin PF06309.6 KHN68907.1 - 0.002 18.0 0.0 0.011 15.6 0.0 2.2 3 0 0 3 3 1 1 Torsin DNA_pol3_delta2 PF13177.1 KHN68907.1 - 0.0033 17.0 0.0 0.28 10.8 0.0 3.3 3 1 0 3 3 2 1 DNA polymerase III, delta subunit AAA_33 PF13671.1 KHN68907.1 - 0.0036 17.1 0.1 2.5 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KHN68907.1 - 0.004 16.8 0.0 0.64 9.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 KHN68907.1 - 0.0049 16.1 0.3 0.84 8.8 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein Bac_DnaA PF00308.13 KHN68907.1 - 0.0092 15.6 0.0 0.35 10.4 0.0 3.2 3 0 0 3 3 2 1 Bacterial dnaA protein AAA_24 PF13479.1 KHN68907.1 - 0.016 14.8 3.9 0.85 9.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain ArsA_ATPase PF02374.10 KHN68907.1 - 0.016 14.2 4.3 2.1 7.3 0.0 3.7 3 1 0 3 3 3 0 Anion-transporting ATPase SRP54 PF00448.17 KHN68907.1 - 0.019 14.4 0.4 3.4 7.0 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 KHN68907.1 - 0.025 13.2 0.1 1.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_3 PF07726.6 KHN68907.1 - 0.037 13.6 0.1 6 6.4 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KHN68907.1 - 0.047 13.6 0.0 5.1 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KHN68907.1 - 0.074 13.5 0.1 5.2 7.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein DnaB_C PF03796.10 KHN68907.1 - 0.23 10.2 4.6 0.24 10.2 0.0 2.8 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Noelin-1 PF12308.3 KHN68907.1 - 1.1 9.1 4.0 2.3 8.0 1.7 2.5 2 0 0 2 2 1 0 Neurogenesis glycoprotein Mlo PF03094.10 KHN68908.1 - 0.53 8.3 4.5 0.56 8.2 3.1 1.1 1 0 0 1 1 1 0 Mlo family SUR7 PF06687.7 KHN68908.1 - 1.8 8.0 8.0 2.2 7.7 5.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF2545 PF10810.3 KHN68908.1 - 3.8 7.9 9.1 7.1 7.1 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2545) O-antigen_lig PF13425.1 KHN68908.1 - 7.3 6.5 10.7 8.8 6.3 7.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TP_methylase PF00590.15 KHN68909.1 - 2.9e-15 56.5 0.0 3.6e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases WD40 PF00400.27 KHN68911.1 - 1.2e-14 53.4 8.9 0.0011 18.7 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 KHN68911.1 - 0.0096 15.6 0.2 4.3 7.1 0.0 2.8 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 KHN68911.1 - 0.041 12.6 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like GTP_EFTU PF00009.22 KHN68912.1 - 1.1e-55 187.9 0.0 2.3e-55 186.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KHN68912.1 - 5.6e-24 84.0 0.0 1.5e-23 82.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KHN68912.1 - 3.1e-18 65.4 0.0 7.4e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KHN68912.1 - 1.6e-10 40.9 0.0 3.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KHN68912.1 - 2.1e-10 40.2 0.1 6.9e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II CBFD_NFYB_HMF PF00808.18 KHN68913.1 - 2.9e-08 33.6 0.4 4.9e-08 32.9 0.3 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KHN68913.1 - 4.8e-07 29.8 0.1 5.3e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SopA PF13981.1 KHN68913.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 SopA-like central domain DUF4378 PF14309.1 KHN68914.1 - 0.013 15.5 0.4 0.016 15.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) IFN-gamma PF00714.12 KHN68914.1 - 0.025 14.3 0.9 0.031 14.0 0.5 1.3 1 1 0 1 1 1 0 Interferon gamma GerA PF03323.8 KHN68914.1 - 0.12 10.5 0.8 0.11 10.5 0.6 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF382 PF04037.8 KHN68915.1 - 1.2e-29 102.7 0.5 3.5e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 KHN68915.1 - 5.8e-18 64.0 2.4 1.1e-17 63.1 1.7 1.5 1 0 0 1 1 1 1 PSP Pkinase PF00069.20 KHN68916.1 - 1.8e-49 168.2 0.1 2e-49 168.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN68916.1 - 2.1e-30 105.6 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN68916.1 - 0.0097 14.8 0.0 0.02 13.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KHN68916.1 - 0.045 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KHN68916.1 - 0.15 11.7 0.1 0.34 10.6 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cation_efflux PF01545.16 KHN68917.1 - 4.5e-61 206.4 11.9 5.8e-61 206.0 8.2 1.0 1 0 0 1 1 1 1 Cation efflux family UPF0233 PF06781.7 KHN68917.1 - 0.12 12.0 1.2 0.41 10.3 0.8 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF3278 PF11683.3 KHN68917.1 - 1.3 9.0 6.8 0.56 10.2 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3278) Methyltransf_4 PF02390.12 KHN68918.1 - 1.3e-43 148.3 0.0 1.7e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 KHN68918.1 - 0.00013 22.3 0.0 0.0056 17.1 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.9 KHN68918.1 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KHN68918.1 - 0.0002 21.8 0.0 0.00041 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KHN68918.1 - 0.00067 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KHN68918.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KHN68918.1 - 0.0029 17.3 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KHN68918.1 - 0.0032 17.1 0.0 0.01 15.5 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN68918.1 - 0.0057 16.2 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KHN68918.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KHN68918.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KHN68918.1 - 0.022 15.2 0.1 0.077 13.4 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_20 PF12147.3 KHN68918.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase AP_endonuc_2 PF01261.19 KHN68920.1 - 1e-29 103.3 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SNARE PF05739.14 KHN68921.1 - 7e-06 25.6 6.3 2.4e-05 23.9 2.3 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KHN68921.1 - 0.0026 17.8 17.8 0.0047 17.0 4.2 2.8 2 1 1 3 3 3 2 Syntaxin DUF4446 PF14584.1 KHN68921.1 - 0.1 12.4 0.3 0.1 12.4 0.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) Laminin_II PF06009.7 KHN68921.1 - 0.11 12.2 9.4 1.1 8.9 2.0 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF2721 PF11026.3 KHN68921.1 - 0.14 11.8 4.4 0.67 9.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Cupin_8 PF13621.1 KHN68921.1 - 0.15 11.5 5.1 0.37 10.2 3.5 1.8 1 1 0 1 1 1 0 Cupin-like domain RE_MjaI PF09568.5 KHN68921.1 - 0.16 11.4 6.2 0.038 13.5 0.5 2.1 2 0 0 2 2 2 0 MjaI restriction endonuclease HAUS-augmin3 PF14932.1 KHN68921.1 - 0.17 11.0 11.9 1 8.4 2.4 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spectrin PF00435.16 KHN68921.1 - 0.19 12.0 6.6 3.6 7.9 0.7 2.7 3 0 0 3 3 3 0 Spectrin repeat FlaC_arch PF05377.6 KHN68921.1 - 0.22 11.4 3.8 0.18 11.7 0.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 KHN68921.1 - 0.32 9.9 12.0 0.49 9.2 0.8 2.1 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-18_N PF10496.4 KHN68921.1 - 0.51 10.2 6.4 0.19 11.5 0.4 2.8 2 1 1 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Folliculin PF11704.3 KHN68921.1 - 0.53 9.8 7.5 1.4 8.5 0.9 2.5 1 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport HSBP1 PF06825.7 KHN68921.1 - 0.61 9.7 4.4 0.63 9.6 0.4 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 zf-CHY PF05495.7 KHN68922.1 - 1.7e-17 63.3 30.7 4.1e-16 58.8 10.3 3.3 3 0 0 3 3 3 3 CHY zinc finger ABC_tran PF00005.22 KHN68923.1 - 2.6e-35 121.7 0.2 2e-16 60.5 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KHN68923.1 - 9.2e-11 41.3 8.4 0.00061 19.0 0.1 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.10 KHN68923.1 - 1.1e-10 40.9 0.9 1.1e-10 40.9 0.6 2.1 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KHN68923.1 - 7.6e-10 39.2 20.6 2.9e-05 24.1 5.5 4.2 3 2 0 4 4 3 3 AAA domain AAA_15 PF13175.1 KHN68923.1 - 3.8e-09 36.1 18.1 0.034 13.1 0.1 4.2 2 2 2 4 4 4 4 AAA ATPase domain AAA_29 PF13555.1 KHN68923.1 - 2e-06 27.2 0.2 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_7 PF12838.2 KHN68923.1 - 1.4e-05 25.3 5.2 0.00066 20.0 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 KHN68923.1 - 1.9e-05 24.2 9.1 0.004 16.9 1.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain DUF258 PF03193.11 KHN68923.1 - 5.3e-05 22.4 2.9 0.038 13.1 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4 PF00037.22 KHN68923.1 - 7.5e-05 22.1 2.4 7.5e-05 22.1 1.6 3.0 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.1 KHN68923.1 - 0.00023 21.1 0.2 0.023 14.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 KHN68923.1 - 0.0037 17.4 0.1 1.5 9.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KHN68923.1 - 0.0053 16.9 0.1 5.2 7.2 0.0 3.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 KHN68923.1 - 0.007 16.0 0.6 0.28 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KHN68923.1 - 0.012 15.7 0.8 3.3 7.8 0.0 3.5 3 1 0 3 3 3 0 AAA domain VirE PF05272.6 KHN68923.1 - 0.012 15.1 0.1 2 7.8 0.0 3.1 3 0 0 3 3 3 0 Virulence-associated protein E Fer4_2 PF12797.2 KHN68923.1 - 0.021 14.7 1.8 0.021 14.7 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 KHN68923.1 - 0.021 15.0 12.9 0.089 13.0 9.0 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 KHN68923.1 - 0.024 15.1 3.5 0.024 15.1 2.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.1 KHN68923.1 - 0.026 14.3 13.2 0.051 13.4 9.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Miro PF08477.8 KHN68923.1 - 0.036 14.5 0.6 25 5.3 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein SbcCD_C PF13558.1 KHN68923.1 - 0.05 13.5 0.2 8.1 6.4 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 KHN68923.1 - 0.12 11.8 0.3 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KHN68923.1 - 0.14 11.5 0.1 14 5.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain Fer4_8 PF13183.1 KHN68923.1 - 0.14 12.1 11.0 0.4 10.7 7.7 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain AAA_23 PF13476.1 KHN68923.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.6 2 1 0 2 2 1 0 AAA domain Fer4_10 PF13237.1 KHN68923.1 - 0.28 11.0 16.8 1 9.2 11.9 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 KHN68923.1 - 2.3 8.7 14.2 0.18 12.1 2.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_16 PF13484.1 KHN68923.1 - 3.1 8.6 12.8 0.14 12.9 1.1 2.6 1 1 0 2 2 2 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.18 KHN68923.1 - 5.2 7.0 6.0 24 4.9 0.3 3.3 2 2 0 2 2 2 0 50S ribosome-binding GTPase Sad1_UNC PF07738.8 KHN68924.1 - 5.7e-21 74.7 0.1 1e-20 73.8 0.1 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 KHN68924.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain MFS_1 PF07690.11 KHN68925.1 - 0.013 14.2 31.2 0.058 12.1 21.6 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily PseudoU_synth_1 PF01416.15 KHN68926.1 - 8.3e-19 67.9 0.0 2.6e-10 40.6 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ribosomal_S19e PF01090.14 KHN68927.1 - 2.3e-27 95.1 0.0 2.6e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e ORF6N PF10543.4 KHN68927.1 - 0.11 12.5 0.0 20 5.2 0.0 2.7 3 0 0 3 3 3 0 ORF6N domain TGT PF01702.13 KHN68928.1 - 1.6e-08 34.1 0.3 3.2e-08 33.1 0.1 1.5 2 0 0 2 2 2 1 Queuine tRNA-ribosyltransferase PA-IIL PF07472.6 KHN68928.1 - 0.084 13.0 0.1 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) Pho88 PF10032.4 KHN68929.1 - 6.1e-32 110.3 4.3 7.4e-32 110.1 3.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4328 PF14219.1 KHN68929.1 - 0.11 11.7 0.5 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) TatC PF00902.13 KHN68929.1 - 1.4 8.2 6.3 0.21 10.9 1.4 1.7 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) SUI1 PF01253.17 KHN68930.1 - 1.4e-12 47.2 1.6 1.9e-12 46.8 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRM_5 PF13893.1 KHN68931.1 - 6.3e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN68931.1 - 3.3e-07 29.8 0.0 7.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN68931.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 KHN68932.1 - 4e-28 98.0 0.0 4.6e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN68932.1 - 0.0044 16.3 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Borrelia_P13 PF05628.7 KHN68932.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 Myb_DNA-binding PF00249.26 KHN68934.1 - 9.2e-30 102.4 2.5 5e-14 52.0 0.9 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KHN68934.1 - 1.2e-25 89.3 4.0 7.2e-17 61.2 0.3 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KHN68934.1 - 0.16 12.1 0.9 1.7 8.8 0.1 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RabGAP-TBC PF00566.13 KHN68935.1 - 3.3e-45 154.2 3.4 4.4e-45 153.7 2.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Tetraspannin PF00335.15 KHN68936.1 - 1.9e-10 40.3 11.2 3.3e-10 39.6 7.8 1.3 1 1 0 1 1 1 1 Tetraspanin family SirB PF04247.7 KHN68936.1 - 0.99 9.1 14.1 0.13 11.9 6.5 1.9 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF465 PF04325.8 KHN68937.1 - 0.012 15.3 2.3 0.012 15.3 1.6 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF465) Mnd1 PF03962.10 KHN68937.1 - 0.016 14.8 7.2 0.016 14.8 5.0 4.5 2 1 2 4 4 4 0 Mnd1 family DUF3209 PF11483.3 KHN68937.1 - 0.11 12.8 0.4 0.11 12.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3209) Filament PF00038.16 KHN68937.1 - 0.12 11.8 43.1 0.27 10.6 5.0 4.0 2 1 2 4 4 4 0 Intermediate filament protein Reo_sigmaC PF04582.7 KHN68937.1 - 0.14 11.3 3.9 0.81 8.8 0.1 2.7 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KHN68937.1 - 0.17 11.6 0.2 0.17 11.6 0.1 5.2 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) UDPGT PF00201.13 KHN68937.1 - 7.3 4.9 6.7 9.1 4.6 0.6 2.2 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase PUF PF00806.14 KHN68939.1 - 1.7e-44 146.8 11.3 3.2e-07 29.4 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat FA_FANCE PF11510.3 KHN68939.1 - 0.0096 15.0 0.1 0.16 11.0 0.0 2.2 2 0 0 2 2 2 1 Fanconi Anaemia group E protein FANCE HNOB PF07700.10 KHN68939.1 - 0.046 13.2 0.8 26 4.2 0.0 3.9 2 1 2 4 4 4 0 Heme NO binding Aa_trans PF01490.13 KHN68940.1 - 4.6e-35 120.8 35.9 6.8e-35 120.3 24.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0370 PF13980.1 KHN68940.1 - 0.16 11.8 0.8 0.52 10.1 0.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) WD40 PF00400.27 KHN68941.1 - 9.7e-48 158.4 23.9 8.2e-11 41.3 0.8 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KHN68941.1 - 3.6e-40 137.3 10.3 9e-40 136.0 7.1 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 KHN68941.1 - 0.021 12.9 0.2 0.15 10.2 0.1 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Arm PF00514.18 KHN68942.1 - 8.8e-38 126.8 5.8 1.4e-10 40.5 0.0 8.1 8 1 0 8 8 8 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KHN68942.1 - 5.4e-14 52.2 0.2 4.6e-05 23.6 0.0 4.0 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 KHN68942.1 - 3.7e-13 49.5 0.2 3.7e-07 30.4 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KHN68942.1 - 1.6e-08 33.8 3.8 0.002 18.0 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat IBB PF01749.15 KHN68942.1 - 1.2e-07 31.7 3.1 2.3e-07 30.8 2.2 1.4 1 0 0 1 1 1 1 Importin beta binding domain Adaptin_N PF01602.15 KHN68942.1 - 0.022 13.0 0.6 0.13 10.5 0.2 2.3 2 1 0 2 2 2 0 Adaptin N terminal region RICTOR_V PF14668.1 KHN68942.1 - 0.086 12.7 3.4 12 5.9 0.0 3.6 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Aminotran_5 PF00266.14 KHN68943.1 - 1e-83 281.1 0.0 1.2e-83 280.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KHN68943.1 - 4.4e-09 35.8 0.3 9.6e-09 34.7 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KHN68943.1 - 0.024 13.7 0.1 0.032 13.2 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KHN68943.1 - 0.069 11.5 0.0 0.098 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain UDPGP PF01704.13 KHN68944.1 - 1.4e-25 89.6 0.3 2e-25 89.1 0.2 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KHN68944.1 - 7.7e-07 29.3 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KHN68944.1 - 0.002 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.14 KHN68944.1 - 0.0024 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MSC PF09402.5 KHN68945.1 - 6.7e-26 90.7 9.1 3.8e-18 65.2 2.1 3.0 2 1 1 3 3 3 2 Man1-Src1p-C-terminal domain YABBY PF04690.8 KHN68945.1 - 0.022 15.0 0.5 0.075 13.2 0.0 2.1 2 0 0 2 2 2 0 YABBY protein NMN_transporter PF04973.7 KHN68946.1 - 0.045 13.2 0.8 0.045 13.2 0.5 2.1 2 1 0 2 2 2 0 Nicotinamide mononucleotide transporter Nsp1_C PF05064.8 KHN68947.1 - 0.014 14.9 2.7 0.014 14.9 1.9 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region Hemerythrin PF01814.18 KHN68947.1 - 0.17 12.0 1.7 0.33 11.1 1.2 1.4 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain HSP70 PF00012.15 KHN68948.1 - 1.9e-13 49.2 8.8 1.9e-13 49.2 6.1 2.8 3 1 0 3 3 3 1 Hsp70 protein RseA_N PF03872.8 KHN68949.1 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain Sec20 PF03908.8 KHN68951.1 - 5.3e-08 32.4 1.8 8.4e-08 31.8 0.6 1.8 1 1 0 1 1 1 1 Sec20 DUF547 PF04784.9 KHN68951.1 - 0.0053 16.6 0.1 0.14 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Pecanex_C PF05041.10 KHN68951.1 - 0.036 13.0 0.5 0.052 12.5 0.3 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) TMPIT PF07851.8 KHN68951.1 - 0.04 13.0 5.5 0.054 12.5 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein AnfO_nitrog PF09582.5 KHN68951.1 - 0.062 12.4 1.2 0.083 12.0 0.8 1.1 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) FTHFS PF01268.14 KHN68951.1 - 0.07 11.1 0.6 0.086 10.8 0.4 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase DUF2116 PF09889.4 KHN68951.1 - 0.08 12.7 3.3 0.11 12.3 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF1542 PF07564.6 KHN68951.1 - 0.1 12.5 1.4 0.33 10.9 0.8 2.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) LMBR1 PF04791.11 KHN68951.1 - 0.23 9.9 3.2 0.28 9.7 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2743 PF10899.3 KHN68951.1 - 0.69 9.2 7.3 0.66 9.3 3.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2743) Nup54 PF13874.1 KHN68951.1 - 7.8 6.1 8.3 15 5.2 2.8 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.5 KHN68951.1 - 8.7 6.4 10.2 21 5.2 4.5 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MFS_1 PF07690.11 KHN68952.1 - 2.2e-09 36.5 23.4 6.8e-08 31.6 16.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily FAM91_C PF14648.1 KHN68952.1 - 0.15 10.8 0.2 0.22 10.3 0.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus MFS_1 PF07690.11 KHN68953.1 - 2.6e-10 39.5 26.7 9.4e-09 34.4 17.7 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Nuc_H_symport PF03825.11 KHN68953.1 - 2.5e-09 36.3 19.8 5e-09 35.4 13.7 1.4 1 1 0 1 1 1 1 Nucleoside H+ symporter HEAT PF02985.17 KHN68955.1 - 9.4e-06 25.2 0.0 0.22 11.6 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KHN68955.1 - 1.3e-05 25.4 0.0 0.047 13.9 0.0 4.1 3 1 1 4 4 4 2 HEAT repeats Brix PF04427.13 KHN68956.1 - 2e-22 79.7 0.2 2.6e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain Tex_N PF09371.5 KHN68956.1 - 0.031 13.5 0.7 6 6.1 0.0 2.4 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Not1 PF04054.10 KHN68956.1 - 0.042 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DER1 PF04511.10 KHN68957.1 - 1.8e-39 135.3 11.7 2.2e-39 135.0 8.1 1.1 1 0 0 1 1 1 1 Der1-like family Spt5-NGN PF03439.8 KHN68958.1 - 5.9e-16 57.9 3.3 8.1e-16 57.5 0.9 2.2 2 1 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KHN68958.1 - 3e-12 45.7 28.0 0.0081 15.8 1.3 6.3 6 1 0 6 6 6 5 KOW motif Brix PF04427.13 KHN68959.1 - 9e-12 45.0 0.0 1.5e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Brix domain Septin PF00735.13 KHN68960.1 - 2e-59 200.9 1.6 5.3e-59 199.5 1.1 1.7 1 1 0 1 1 1 1 Septin Borrelia_REV PF03978.8 KHN68960.1 - 0.004 16.8 0.6 0.0079 15.9 0.4 1.5 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein GTP_EFTU PF00009.22 KHN68960.1 - 0.034 13.5 1.1 0.62 9.4 0.5 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN68960.1 - 0.078 12.9 0.2 0.17 11.8 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.27 KHN68962.1 - 2.1e-27 93.9 10.7 2.2e-07 30.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KHN68962.1 - 0.00028 19.3 0.0 0.00048 18.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 KHN68962.1 - 0.0033 15.6 0.1 0.015 13.4 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KHN68962.1 - 0.11 12.8 0.1 73 3.8 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain UQ_con PF00179.21 KHN68963.1 - 4.1e-43 146.1 0.0 4.7e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KHN68963.1 - 0.00017 21.3 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KHN68963.1 - 0.0016 18.3 0.2 0.0019 18.1 0.1 1.5 1 1 0 1 1 1 1 RWD domain SMC_N PF02463.14 KHN68964.1 - 2.5e-17 62.8 30.9 1.4e-16 60.4 21.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KHN68964.1 - 1.5e-05 24.3 0.0 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KHN68964.1 - 2.1e-05 24.6 16.8 3.8e-05 23.7 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_13 PF13166.1 KHN68964.1 - 0.0064 15.0 0.3 0.0064 15.0 0.2 4.9 3 2 1 4 4 4 1 AAA domain AAA_10 PF12846.2 KHN68964.1 - 0.018 14.5 0.1 0.018 14.5 0.0 2.9 2 2 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 KHN68964.1 - 0.058 13.7 91.6 1.5e+04 -28.6 63.1 5.6 1 1 0 1 1 1 0 AAA domain DUF1515 PF07439.6 KHN68964.1 - 0.13 12.1 0.1 0.13 12.1 0.1 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1515) MMR_HSR1 PF01926.18 KHN68964.1 - 0.19 11.7 2.8 0.93 9.4 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase NPV_P10 PF05531.7 KHN68964.1 - 2.5 8.3 13.1 0.17 12.1 0.8 4.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Kinesin PF00225.18 KHN68966.1 - 3.1e-82 275.9 0.3 5.5e-82 275.1 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 KHN68966.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif STE PF02200.11 KHN68967.1 - 9.2e-59 196.3 0.3 2e-58 195.3 0.2 1.6 1 0 0 1 1 1 1 STE like transcription factor CheZ PF04344.8 KHN68968.1 - 0.0016 18.1 0.3 0.0021 17.7 0.2 1.3 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ DUF3381 PF11861.3 KHN68968.1 - 0.011 15.3 2.2 0.017 14.6 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PspB PF06667.7 KHN68968.1 - 0.34 10.8 1.7 0.79 9.6 0.2 2.2 3 0 0 3 3 3 0 Phage shock protein B MSG PF02349.10 KHN68968.1 - 1.5 8.8 9.9 6.1 6.9 1.1 2.3 1 1 1 2 2 2 0 Major surface glycoprotein RNase_PH PF01138.16 KHN68969.1 - 3.6e-05 24.0 0.1 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3237 PF11578.3 KHN68970.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) DUF1256 PF06866.6 KHN68970.1 - 0.028 13.6 0.2 0.28 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1256) Stb3 PF10330.4 KHN68970.1 - 0.044 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative Sin3 binding protein Ribosomal_L29 PF00831.18 KHN68971.1 - 4.8e-08 32.5 5.6 4.8e-08 32.5 3.9 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein DUF4111 PF13427.1 KHN68971.1 - 0.047 13.5 0.3 0.07 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) HD_assoc PF13286.1 KHN68971.1 - 0.049 13.9 0.5 0.12 12.7 0.3 1.8 1 1 1 2 2 2 0 Phosphohydrolase-associated domain DUF3363 PF11843.3 KHN68971.1 - 0.085 11.4 0.4 0.11 11.1 0.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3363) FliH PF02108.11 KHN68971.1 - 0.12 12.2 2.5 0.15 11.9 1.7 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH DUF1444 PF07285.6 KHN68971.1 - 0.15 11.3 3.7 0.21 10.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) Host_attach PF10116.4 KHN68971.1 - 1.4 9.1 4.2 2.3 8.4 0.3 2.1 2 0 0 2 2 2 0 Protein required for attachment to host cells LSM PF01423.17 KHN68972.1 - 3.1e-08 33.0 0.4 4.1e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KHN68972.1 - 0.0002 21.2 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain eIF-5a PF01287.15 KHN68972.1 - 0.14 12.1 0.1 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF2089 PF09862.4 KHN68973.1 - 0.12 12.1 0.3 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Nuf2 PF03800.9 KHN68974.1 - 3e-30 105.1 0.1 8.4e-30 103.6 0.1 1.8 1 0 0 1 1 1 1 Nuf2 family Reo_sigmaC PF04582.7 KHN68974.1 - 1.4e-05 24.4 5.1 0.0051 16.0 0.2 2.4 3 0 0 3 3 3 2 Reovirus sigma C capsid protein APG6 PF04111.7 KHN68974.1 - 0.0033 16.5 27.1 0.025 13.6 8.6 2.2 2 0 0 2 2 2 2 Autophagy protein Apg6 ERM PF00769.14 KHN68974.1 - 0.0044 16.5 26.3 0.15 11.6 8.1 2.2 2 0 0 2 2 2 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 KHN68974.1 - 0.022 14.6 31.8 0.77 9.6 10.4 3.8 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3793 PF12672.2 KHN68974.1 - 0.029 13.9 2.0 0.12 11.9 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3793) MxiH PF09392.5 KHN68974.1 - 0.082 13.4 0.0 13 6.4 0.0 3.3 2 2 0 2 2 2 0 Type III secretion needle MxiH like DUF948 PF06103.6 KHN68974.1 - 0.43 10.4 13.2 1.9 8.4 0.1 5.0 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KHN68974.1 - 0.83 9.2 29.3 0.35 10.4 5.6 2.5 1 1 0 2 2 2 0 IncA protein DUF4140 PF13600.1 KHN68974.1 - 1.4 9.3 17.0 2.5 8.6 0.2 4.1 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.7 KHN68974.1 - 1.9 8.7 10.0 2.8 8.2 0.3 4.4 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Mit_KHE1 PF10173.4 KHN68974.1 - 2 8.2 7.3 0.46 10.3 0.8 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Spectrin PF00435.16 KHN68974.1 - 2.9 8.2 16.5 0.12 12.6 1.1 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF972 PF06156.8 KHN68974.1 - 4 7.8 27.4 4.3 7.7 0.5 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KHN68974.1 - 4.3 7.1 27.1 1.1 9.1 0.8 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 KHN68974.1 - 6.2 6.6 11.2 2.1 8.1 2.1 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.8 KHN68974.1 - 6.8 4.9 8.7 0.41 8.9 0.7 2.1 2 0 0 2 2 2 0 Tweety ADIP PF11559.3 KHN68974.1 - 7.8 6.3 28.8 0.65 9.8 4.5 3.7 2 2 2 4 4 4 0 Afadin- and alpha -actinin-Binding STAT_alpha PF01017.15 KHN68974.1 - 8.7 6.0 20.6 2.5 7.7 4.6 2.5 2 0 0 2 2 2 0 STAT protein, all-alpha domain tRNA-synt_2 PF00152.15 KHN68975.1 - 3e-66 223.4 0.2 4.6e-66 222.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KHN68975.1 - 0.077 12.1 1.4 2.3 7.3 0.0 2.9 3 1 0 3 3 3 0 tRNA synthetases class II core domain (F) BRCA2 PF00634.13 KHN68976.1 - 0.038 13.2 0.1 0.093 12.0 0.0 1.7 1 0 0 1 1 1 0 BRCA2 repeat DUF2415 PF10313.4 KHN68977.1 - 1.7e-10 40.3 0.1 1.9e-08 33.8 0.0 3.5 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KHN68977.1 - 7.7e-09 35.1 5.3 0.021 14.7 0.3 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 KHN68977.1 - 3.5e-05 22.2 0.1 0.084 11.0 0.0 2.4 1 1 1 3 3 3 2 Protein of unknown function (DUF3312) Pectate_lyase_3 PF12708.2 KHN68977.1 - 0.0051 16.9 2.7 0.0061 16.7 0.8 1.8 2 1 0 2 2 2 1 Pectate lyase superfamily protein Fcf1 PF04900.7 KHN68977.1 - 0.022 14.8 0.5 4.3 7.4 0.0 3.4 4 1 1 5 5 5 0 Fcf1 Kelch_6 PF13964.1 KHN68977.1 - 0.058 13.6 0.1 2.2 8.5 0.0 3.1 2 1 1 3 3 3 0 Kelch motif PQQ_2 PF13360.1 KHN68977.1 - 0.079 12.4 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Apc4_WD40 PF12894.2 KHN68977.1 - 0.12 11.8 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NGP1NT PF08153.7 KHN68978.1 - 1.5e-31 108.9 0.2 2.5e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KHN68978.1 - 2.7e-17 62.8 3.0 2.7e-14 53.1 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KHN68978.1 - 2.6e-05 23.5 0.5 0.00021 20.6 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 KHN68978.1 - 5.1e-05 22.5 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KHN68978.1 - 0.0042 16.9 0.1 2.5 7.8 0.0 3.3 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 KHN68978.1 - 0.0063 15.7 0.2 0.18 11.0 0.0 2.7 3 0 0 3 3 3 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KHN68978.1 - 0.0092 15.4 0.0 14 5.0 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 KHN68978.1 - 0.029 14.0 0.2 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IcmL PF11393.3 KHN68978.1 - 0.049 13.5 0.0 5.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Macrophage killing protein with similarity to conjugation protein F-box-like_2 PF13013.1 KHN68978.1 - 0.098 12.3 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain DEAD PF00270.24 KHN68979.1 - 8.4e-37 126.2 0.0 2.7e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN68979.1 - 6.9e-25 86.7 0.0 1.3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN68979.1 - 0.027 14.3 0.0 0.25 11.1 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 KHN68980.1 - 0.26 11.0 16.6 1.2 8.9 11.2 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KHN68980.1 - 0.54 10.3 13.8 0.56 10.2 7.9 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KHN68980.1 - 2.1 8.2 13.1 2.9 7.7 7.9 2.2 2 1 0 2 2 2 0 Ring finger domain XPG_I PF00867.13 KHN68981.1 - 1.9e-18 66.2 0.1 7.5e-18 64.3 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KHN68981.1 - 5.7e-12 45.7 0.1 7.1e-11 42.2 0.0 2.5 1 1 0 1 1 1 1 XPG N-terminal domain Tbf5 PF06331.7 KHN68982.1 - 1.4e-15 56.7 0.0 1.5e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sua5_yciO_yrdC PF01300.13 KHN68983.1 - 9.8e-56 187.8 0.0 1.7e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KHN68983.1 - 1.9e-21 76.4 0.0 2.9e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Nop PF01798.13 KHN68984.1 - 5.4e-44 149.1 0.4 1e-43 148.1 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KHN68984.1 - 2.5e-16 59.1 0.5 5.5e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KHN68984.1 - 1.4e-09 37.9 1.4 5.7e-09 35.9 0.0 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain YIF1 PF03878.10 KHN68985.1 - 1.8e-29 102.6 5.9 4.3e-29 101.3 4.1 1.6 1 1 0 1 1 1 1 YIF1 VID27 PF08553.5 KHN68986.1 - 3.4e-96 323.2 17.9 7.3e-96 322.1 12.4 1.5 1 1 0 1 1 1 1 VID27 cytoplasmic protein PQQ_3 PF13570.1 KHN68986.1 - 0.033 14.4 0.1 2.1 8.7 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.1 KHN68986.1 - 0.059 12.8 0.0 1.2 8.5 0.0 2.5 3 0 0 3 3 3 0 PQQ-like domain FAD_binding_1 PF00667.15 KHN68987.1 - 4.5e-19 68.7 0.0 6.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KHN68987.1 - 2.8e-15 56.8 0.1 6.1e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KHN68987.1 - 0.00094 19.1 0.2 0.0034 17.3 0.1 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF4479 PF14794.1 KHN68987.1 - 0.085 12.4 0.5 3.9 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) PQQ_3 PF13570.1 KHN68988.1 - 4.4 7.7 6.2 3.1 8.1 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain CDC73 PF05179.9 KHN68989.1 - 8.4e-18 64.6 3.2 7e-17 61.6 2.1 2.0 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family WD40 PF00400.27 KHN68990.1 - 8.5e-14 50.8 8.1 5.6e-05 22.8 0.1 6.6 7 1 0 7 7 7 3 WD domain, G-beta repeat PFU PF09070.6 KHN68990.1 - 1.2e-09 38.1 3.3 4e-09 36.5 2.3 1.9 1 1 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PQQ_3 PF13570.1 KHN68990.1 - 0.0058 16.8 0.1 9.4 6.6 0.0 3.8 3 0 0 3 3 3 1 PQQ-like domain Kelch_1 PF01344.20 KHN68990.1 - 0.07 12.6 0.5 0.78 9.3 0.0 2.9 3 1 0 3 3 3 0 Kelch motif SET PF00856.23 KHN68991.1 - 6.1e-21 75.4 1.4 9.9e-20 71.4 1.0 2.5 1 1 0 1 1 1 1 SET domain TCR PF03638.10 KHN68991.1 - 0.74 9.7 42.2 3.5 7.5 11.1 3.2 1 1 1 2 2 2 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Med7 PF05983.6 KHN68992.1 - 0.011 15.5 3.1 0.16 11.7 2.2 2.0 1 1 0 1 1 1 0 MED7 protein WD40 PF00400.27 KHN68993.1 - 1.5e-17 62.7 7.3 2.6e-08 33.4 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat V_ATPase_I PF01496.14 KHN68994.1 - 1.3e-149 499.4 30.2 2.3e-149 498.6 21.0 1.3 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family CHB_HEX PF03173.8 KHN68994.1 - 0.046 13.1 1.3 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Putative carbohydrate binding domain AAA_11 PF13086.1 KHN68995.1 - 2.2e-24 86.3 0.5 1.3e-12 47.8 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.1 KHN68995.1 - 1.2e-20 73.7 9.9 1.9e-12 46.9 0.1 3.9 3 2 1 4 4 4 2 AAA domain Viral_helicase1 PF01443.13 KHN68995.1 - 7.4e-17 61.6 1.4 9.4e-15 54.7 1.0 2.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Dna2 PF08696.6 KHN68995.1 - 4.4e-13 49.0 9.7 7e-12 45.1 3.2 3.6 2 1 1 3 3 3 1 DNA replication factor Dna2 AAA_30 PF13604.1 KHN68995.1 - 4.6e-09 36.1 0.0 2.4e-06 27.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.1 KHN68995.1 - 1.7e-07 31.3 0.0 5.3e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.12 KHN68995.1 - 4.3e-05 23.5 3.1 4.7e-05 23.3 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_19 PF13245.1 KHN68995.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 KHN68995.1 - 0.0032 17.1 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 Helicase Mg_chelatase PF01078.16 KHN68995.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 KHN68995.1 - 0.051 13.7 0.0 0.2 11.8 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KHN68995.1 - 0.053 12.4 0.1 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein LSM PF01423.17 KHN68996.1 - 3.9e-12 45.5 0.1 5.6e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Cullin PF00888.17 KHN68997.1 - 4.2e-08 32.2 7.7 4.2e-08 32.2 5.4 2.0 3 0 0 3 3 3 1 Cullin family SEP PF08059.8 KHN68998.1 - 0.00011 22.3 0.1 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBA PF00627.26 KHN68998.1 - 0.0029 17.4 0.2 0.0052 16.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Cbl_N3 PF02762.9 KHN68998.1 - 0.02 14.5 0.1 0.56 9.8 0.0 2.3 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Cyclin_N PF00134.18 KHN68999.1 - 4e-06 26.3 0.0 1.6e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain AAA PF00004.24 KHN69000.1 - 8.2e-45 152.2 0.1 6.4e-44 149.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN69000.1 - 1.6e-07 31.1 0.1 8.6e-07 28.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KHN69000.1 - 5.4e-07 29.6 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KHN69000.1 - 1e-06 28.9 0.0 4.9e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KHN69000.1 - 7.2e-06 26.1 0.3 0.00036 20.6 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KHN69000.1 - 3.7e-05 22.8 0.0 0.00012 21.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KHN69000.1 - 0.00011 21.9 0.1 0.00027 20.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KHN69000.1 - 0.00012 22.8 0.0 0.0003 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KHN69000.1 - 0.00027 20.4 0.0 0.00056 19.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KHN69000.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KHN69000.1 - 0.00077 18.2 0.0 0.0017 17.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KHN69000.1 - 0.0009 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KHN69000.1 - 0.001 18.1 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KHN69000.1 - 0.0029 17.8 0.2 0.017 15.4 0.0 2.4 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.1 KHN69000.1 - 0.0031 17.5 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KHN69000.1 - 0.0036 16.8 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KHN69000.1 - 0.0037 16.4 0.0 0.0086 15.2 0.0 1.6 1 0 0 1 1 1 1 KaiC PhoH PF02562.11 KHN69000.1 - 0.0039 16.4 0.0 0.047 12.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 KHN69000.1 - 0.0049 16.2 0.2 0.057 12.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KHN69000.1 - 0.0057 15.8 0.1 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KHN69000.1 - 0.0084 15.0 0.0 0.019 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 KHN69000.1 - 0.011 15.2 0.2 0.065 12.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain HR1 PF02185.11 KHN69000.1 - 0.016 14.9 0.4 0.037 13.7 0.2 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_24 PF13479.1 KHN69000.1 - 0.017 14.7 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Histone PF00125.19 KHN69000.1 - 0.019 15.0 0.2 0.058 13.5 0.0 1.9 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 RNA_helicase PF00910.17 KHN69000.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KHN69000.1 - 0.032 13.0 0.0 0.077 11.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 KHN69000.1 - 0.037 14.0 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KHN69000.1 - 0.045 14.0 0.2 0.45 10.8 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.12 KHN69000.1 - 0.051 12.4 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KHN69000.1 - 0.097 12.3 0.0 0.41 10.3 0.0 1.9 1 1 1 2 2 2 0 NACHT domain zf-HC5HC2H_2 PF13832.1 KHN69001.1 - 8.5e-20 70.7 12.2 8.5e-20 70.7 8.4 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KHN69001.1 - 5.4e-07 29.6 9.6 5.4e-07 29.6 6.7 2.9 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 KHN69001.1 - 9.4e-06 24.8 0.6 9.4e-06 24.8 0.4 3.7 3 0 0 3 3 3 1 PHD-finger DUF1076 PF06416.7 KHN69001.1 - 0.019 14.6 0.7 0.084 12.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1076) IKI3 PF04762.7 KHN69002.1 - 7.9e-18 63.7 0.6 2.3e-10 39.0 0.0 4.0 4 1 1 5 5 5 4 IKI3 family Prenyltransf PF01255.14 KHN69003.1 - 2.9e-47 160.6 2.0 3.6e-31 108.0 0.3 2.1 1 1 1 2 2 2 2 Putative undecaprenyl diphosphate synthase HTH_19 PF12844.2 KHN69004.1 - 0.12 12.3 3.7 1.2 9.2 0.7 2.8 1 1 1 2 2 2 0 Helix-turn-helix domain Reo_sigmaC PF04582.7 KHN69004.1 - 0.21 10.7 6.9 0.062 12.4 2.1 1.9 2 1 0 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 KHN69004.1 - 0.35 9.8 27.5 0.48 9.4 5.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Osmo_CC PF08946.5 KHN69004.1 - 0.56 10.2 9.8 0.2 11.6 1.7 2.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Uds1 PF15456.1 KHN69004.1 - 4 7.4 17.1 2.6 8.0 1.6 2.6 2 0 0 2 2 2 0 Up-regulated During Septation DUF948 PF06103.6 KHN69004.1 - 5.8 6.8 7.6 16 5.4 1.7 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SNF2_N PF00176.18 KHN69005.1 - 2.4e-70 236.6 0.3 2.4e-70 236.6 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 KHN69005.1 - 5.2e-33 114.0 19.1 1.1e-32 112.9 13.3 1.6 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.26 KHN69005.1 - 8.8e-18 63.9 0.0 5.5e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 KHN69005.1 - 0.23 10.9 11.4 1.8 8.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF4337 PF14235.1 KHN69005.1 - 4 7.2 9.0 8.4 6.2 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SMC_N PF02463.14 KHN69007.1 - 4.3e-52 176.5 0.0 7.8e-52 175.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KHN69007.1 - 3.2e-21 75.5 0.0 7.3e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KHN69007.1 - 8e-11 42.6 52.7 2e-10 41.3 18.4 4.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KHN69007.1 - 5.9e-10 39.5 13.6 1.6e-05 25.0 0.0 4.0 4 1 1 5 5 5 2 AAA domain AAA_15 PF13175.1 KHN69007.1 - 1.1e-08 34.5 47.0 2.2e-06 26.9 13.4 3.8 2 2 1 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 KHN69007.1 - 9.7e-07 28.2 0.0 2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KHN69007.1 - 3.7e-06 27.2 2.3 0.0039 17.4 0.2 3.7 2 2 0 2 2 2 2 ABC transporter DUF2813 PF11398.3 KHN69007.1 - 1e-05 24.7 1.3 2.6e-05 23.5 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) DUF2802 PF10975.3 KHN69007.1 - 0.0061 16.2 0.2 0.033 13.9 0.1 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2802) Miro PF08477.8 KHN69007.1 - 0.0089 16.5 0.4 0.055 13.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 KHN69007.1 - 0.069 12.7 0.0 12 5.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 KHN69007.1 - 0.076 13.0 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 KHN69007.1 - 0.11 11.8 0.0 3.8 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KHN69007.1 - 4.1 6.8 7.8 5.6 6.3 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF2356 PF10189.4 KHN69009.1 - 0.0081 15.2 0.2 0.0081 15.2 0.2 2.4 2 1 0 3 3 3 1 Conserved protein (DUF2356) CemA PF03040.9 KHN69010.1 - 0.04 13.5 2.1 0.068 12.7 1.5 1.5 1 0 0 1 1 1 0 CemA family C1_1 PF00130.17 KHN69010.1 - 0.059 13.1 1.0 0.13 12.0 0.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TB2_DP1_HVA22 PF03134.14 KHN69011.1 - 5.4e-16 58.1 0.6 8.1e-16 57.5 0.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family dCMP_cyt_deam_1 PF00383.17 KHN69012.1 - 1.1e-19 70.0 3.8 1.8e-19 69.2 2.6 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Branch PF02485.16 KHN69012.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 Core-2/I-Branching enzyme Bd3614-deam PF14439.1 KHN69012.1 - 0.38 10.5 3.0 0.47 10.3 0.3 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase Myosin_head PF00063.16 KHN69013.1 - 7.1e-120 401.1 15.6 6.9e-104 348.2 7.0 2.6 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.14 KHN69013.1 - 5.8e-21 74.3 0.8 1.6e-20 72.9 0.6 1.8 1 0 0 1 1 1 1 DIL domain Sigma54_activat PF00158.21 KHN69013.1 - 0.0051 16.3 0.2 0.033 13.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain Pox_A_type_inc PF04508.7 KHN69013.1 - 0.012 15.3 3.8 0.066 13.0 2.6 2.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_16 PF13191.1 KHN69013.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KHN69013.1 - 0.078 13.1 0.1 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain CagZ PF09053.5 KHN69015.1 - 0.18 11.1 4.4 0.051 12.8 0.6 1.8 2 0 0 2 2 2 0 CagZ DDT PF02791.12 KHN69017.1 - 0.0094 15.7 0.2 0.023 14.4 0.1 1.7 1 0 0 1 1 1 1 DDT domain TMEM237 PF15383.1 KHN69017.1 - 0.019 14.1 0.4 0.028 13.5 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 ALMS_motif PF15309.1 KHN69017.1 - 0.21 11.3 4.9 0.13 12.0 0.5 2.2 2 0 0 2 2 2 0 ALMS motif DUF3617 PF12276.3 KHN69017.1 - 1.9 7.9 6.6 0.33 10.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) APG9 PF04109.11 KHN69018.1 - 2.6e-10 39.7 11.9 5.3e-10 38.7 8.2 1.5 1 0 0 1 1 1 1 Autophagy protein Apg9 NapE PF06796.6 KHN69018.1 - 0.1 11.9 0.3 0.27 10.5 0.2 1.7 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE HemY_N PF07219.8 KHN69018.1 - 0.1 12.1 0.5 18 4.9 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF1218 PF06749.7 KHN69018.1 - 8.8 6.8 8.1 39 4.7 1.9 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) CAF1A PF12253.3 KHN69019.1 - 1.8e-07 31.1 2.2 4.2e-07 29.9 1.5 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Nucleoporin_FG PF13634.1 KHN69022.1 - 0.28 11.4 7.0 0.9 9.7 3.3 2.2 2 0 0 2 2 2 0 Nucleoporin FG repeat region zf-RING_2 PF13639.1 KHN69023.1 - 9.7e-07 28.5 4.9 2.4e-06 27.2 3.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KHN69023.1 - 1.9e-06 27.3 5.9 1.9e-06 27.3 4.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN69023.1 - 7.3e-06 25.5 4.9 1.7e-05 24.4 3.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69023.1 - 8.6e-06 25.3 10.9 1e-05 25.1 5.4 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KHN69023.1 - 3.1e-05 23.8 8.9 3.1e-05 23.8 6.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KHN69023.1 - 0.0014 18.7 5.2 0.0052 16.8 3.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger Rtf2 PF04641.7 KHN69023.1 - 0.061 12.5 4.8 0.062 12.4 3.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.1 KHN69023.1 - 0.066 12.9 2.0 0.066 12.9 1.4 2.1 1 1 1 2 2 2 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 KHN69023.1 - 0.2 11.1 0.5 0.2 11.1 0.3 3.6 2 1 2 4 4 4 0 Rad50 zinc hook motif TerY-C PF15616.1 KHN69023.1 - 0.21 11.4 4.4 0.34 10.8 3.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 KHN69023.1 - 0.22 11.1 6.7 0.66 9.6 4.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KHN69023.1 - 0.3 10.8 4.0 0.51 10.1 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 KHN69023.1 - 0.44 10.2 4.0 0.69 9.6 2.8 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 KHN69023.1 - 1.5 8.4 8.6 3.2 7.3 4.9 2.2 2 1 0 2 2 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 KHN69023.1 - 2.6 7.9 8.2 1.1 9.1 3.3 2.2 2 1 0 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.6 KHN69023.1 - 3.3 7.2 0.0 3.3 7.2 0.0 3.3 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.5 KHN69023.1 - 3.7 7.5 6.8 1.6 8.7 0.8 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-C3HC4_4 PF15227.1 KHN69023.1 - 4.7 7.1 14.4 0.27 11.1 5.5 2.3 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Nudix_N_2 PF14803.1 KHN69023.1 - 4.9 6.9 12.5 0.99 9.1 2.6 3.1 2 1 1 3 3 3 0 Nudix N-terminal DUF1272 PF06906.6 KHN69023.1 - 5.8 6.8 10.4 11 5.9 4.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) IBR PF01485.16 KHN69023.1 - 8.6 6.3 9.0 2.5 8.0 2.3 2.8 2 1 1 3 3 3 0 IBR domain RNase_P_Rpp14 PF01900.14 KHN69024.1 - 3.2e-13 49.4 0.1 3.8e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 Rpp14/Pop5 family PK PF00224.16 KHN69025.1 - 4.4e-108 360.9 7.4 6e-108 360.5 5.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 KHN69025.1 - 8.7e-05 21.4 1.1 0.00052 18.9 0.3 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PK_C PF02887.11 KHN69025.1 - 0.013 15.0 0.3 0.034 13.6 0.0 1.8 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 KHN69025.1 - 0.05 12.4 0.2 0.05 12.4 0.1 2.2 2 1 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain TPP_enzyme_M PF00205.17 KHN69025.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Arv1 PF04161.8 KHN69027.1 - 3.8e-22 79.2 14.2 6.2e-22 78.5 9.8 1.3 1 0 0 1 1 1 1 Arv1-like family YibE_F PF07907.6 KHN69027.1 - 0.011 14.9 7.1 0.016 14.3 4.9 1.3 1 0 0 1 1 1 0 YibE/F-like protein Zn-ribbon_8 PF09723.5 KHN69027.1 - 0.031 14.2 4.4 0.031 14.2 3.0 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KHN69027.1 - 0.043 13.5 1.1 0.043 13.5 0.8 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 KHN69027.1 - 0.059 13.0 1.5 0.13 11.9 1.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1761 PF08570.5 KHN69027.1 - 3.8 7.5 8.7 3 7.8 4.3 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) zf-DNL PF05180.7 KHN69027.1 - 3.9 7.2 8.7 9.5 6.0 3.8 2.9 2 1 1 3 3 3 0 DNL zinc finger Hist_deacetyl PF00850.14 KHN69028.1 - 5.1e-63 213.2 0.1 1e-62 212.2 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain La PF05383.12 KHN69029.1 - 2.2e-20 72.2 0.1 6.4e-20 70.7 0.1 1.9 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 KHN69029.1 - 1.7e-07 31.0 0.1 9e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN69029.1 - 0.0037 16.8 1.2 0.012 15.1 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF402 PF04167.8 KHN69029.1 - 0.065 13.0 0.0 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF402) Peptidase_C97 PF05903.9 KHN69030.1 - 3.4e-31 108.0 0.0 3.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KHN69030.1 - 0.15 11.9 0.1 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase WW PF00397.21 KHN69031.1 - 3.5e-13 49.1 6.2 9.3e-07 28.6 0.1 3.2 4 0 0 4 4 4 2 WW domain DUF2296 PF10058.4 KHN69032.1 - 2.4e-17 62.3 1.1 4e-17 61.6 0.7 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4355 PF14265.1 KHN69032.1 - 0.011 15.7 0.7 0.011 15.7 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF2721 PF11026.3 KHN69032.1 - 0.17 11.4 1.6 0.22 11.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Proteasome PF00227.21 KHN69033.1 - 3.8e-46 156.7 0.4 4.4e-46 156.5 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Zip PF02535.17 KHN69035.1 - 4.3e-35 121.2 16.6 5.3e-35 120.9 11.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Brr6_like_C_C PF10104.4 KHN69035.1 - 0.19 11.2 0.1 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain XRN_N PF03159.13 KHN69037.1 - 3.2e-85 285.3 0.0 4.9e-85 284.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_4 PF14392.1 KHN69037.1 - 0.00077 19.0 1.2 0.00077 19.0 0.8 2.4 3 0 0 3 3 3 1 Zinc knuckle C6_DPF PF10170.4 KHN69037.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Cysteine-rich domain DNA_pol_E_B PF04042.11 KHN69038.1 - 8.3e-22 77.4 0.0 1.5e-21 76.6 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B tRNA_anti-codon PF01336.20 KHN69038.1 - 0.02 14.7 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RRN3 PF05327.6 KHN69039.1 - 1.2 7.1 15.2 5.1 5.0 4.7 3.3 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 PDEase_I PF00233.14 KHN69040.1 - 5.9e-11 42.5 0.0 1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 KHN69040.1 - 0.004 17.1 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 HD domain NARG2_C PF10505.4 KHN69040.1 - 0.05 12.7 0.1 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus THUMP PF02926.12 KHN69041.1 - 1.7e-06 27.9 5.5 1.4e-05 25.0 3.3 2.6 1 1 1 2 2 2 1 THUMP domain PhosphMutase PF10143.4 KHN69041.1 - 0.023 14.3 0.1 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase DUF1465 PF07323.7 KHN69041.1 - 0.062 12.8 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) CENP-P PF13096.1 KHN69041.1 - 0.073 12.3 1.4 0.11 11.7 0.9 1.5 1 1 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P GTP_EFTU PF00009.22 KHN69042.1 - 3.5e-16 59.1 0.7 5.5e-16 58.5 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN69042.1 - 1.1e-06 28.5 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KHN69042.1 - 1.2e-06 28.9 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein EFG_C PF00679.19 KHN69042.1 - 7.8e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus UPF0079 PF02367.12 KHN69042.1 - 0.0042 16.6 0.1 0.075 12.6 0.0 2.6 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 KHN69042.1 - 0.0055 15.5 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein ABC_tran PF00005.22 KHN69042.1 - 0.016 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KHN69042.1 - 0.028 13.5 0.0 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Ribosomal_S24e PF01282.14 KHN69042.1 - 0.035 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S24e CbiA PF01656.18 KHN69042.1 - 0.4 10.0 2.3 0.6 9.4 0.1 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.13 KHN69043.1 - 9.4e-64 215.1 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KHN69043.1 - 3.2e-08 33.5 0.0 9.4e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KHN69043.1 - 5.1e-06 26.4 0.9 0.0057 16.4 0.3 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 KHN69043.1 - 0.0001 21.4 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 KHN69043.1 - 0.00054 19.4 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 KHN69043.1 - 0.0018 17.1 0.0 0.0076 15.1 0.0 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 KHN69043.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 KHN69043.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KHN69043.1 - 0.043 13.0 0.3 0.2 10.8 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 KHN69043.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 KHN69043.1 - 0.078 13.2 0.1 0.098 12.9 0.1 1.4 1 1 0 1 1 1 0 ABC transporter RNase_PH PF01138.16 KHN69044.1 - 0.047 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Cyclin_N PF00134.18 KHN69045.1 - 0.00084 18.9 0.1 0.0017 17.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 KHN69045.1 - 0.013 15.3 0.1 0.044 13.5 0.1 2.0 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Elf1 PF05129.8 KHN69046.1 - 1.1e-22 79.4 7.5 1.3e-22 79.2 5.2 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like TerY-C PF15616.1 KHN69046.1 - 0.013 15.4 1.8 0.015 15.2 1.3 1.1 1 0 0 1 1 1 0 TerY-C metal binding domain FdhE PF04216.7 KHN69046.1 - 0.068 12.8 2.1 0.078 12.6 1.5 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Ribosomal_L37ae PF01780.14 KHN69046.1 - 0.099 12.5 2.4 0.14 12.0 1.7 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-Sec23_Sec24 PF04810.10 KHN69046.1 - 0.11 12.0 1.0 0.11 12.0 0.7 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 KHN69046.1 - 0.26 11.6 1.4 7.4 7.0 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.7 KHN69046.1 - 1.4 8.9 7.8 3.7 7.6 0.6 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain ThiF PF00899.16 KHN69048.1 - 1.6e-22 79.8 1.4 1.6e-22 79.8 1.0 2.1 2 1 0 2 2 2 1 ThiF family Pyr_redox_2 PF07992.9 KHN69048.1 - 0.0018 18.1 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KHN69048.1 - 0.0057 16.6 0.4 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 KHN69048.1 - 0.036 14.1 0.2 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KHN69048.1 - 0.16 10.9 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Semialdhyde_dh PF01118.19 KHN69048.1 - 0.19 12.0 2.0 18 5.6 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TPR_11 PF13414.1 KHN69049.1 - 8.8e-17 60.5 3.2 1.1e-10 41.0 0.7 4.0 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 KHN69049.1 - 1.2e-13 50.0 2.9 0.0011 18.5 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69049.1 - 8.3e-13 48.0 3.2 5e-08 32.7 0.1 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KHN69049.1 - 1.3e-11 43.4 1.4 0.034 14.0 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KHN69049.1 - 3.5e-05 23.6 1.4 1.3 9.4 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KHN69049.1 - 0.00016 21.2 2.2 3.7 7.5 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KHN69049.1 - 0.00017 22.1 2.2 0.33 11.6 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KHN69049.1 - 0.0017 18.4 5.5 0.97 9.6 1.2 4.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KHN69049.1 - 0.035 14.4 3.9 8.8 6.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KHN69049.1 - 0.11 12.4 3.4 1.4 8.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MCM_bind PF09739.4 KHN69050.1 - 0.024 14.2 0.1 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HEAT PF02985.17 KHN69052.1 - 7.2e-11 41.2 0.0 4 7.7 0.0 6.3 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 KHN69052.1 - 8.6e-10 38.7 0.0 0.00083 19.5 0.0 4.2 3 1 2 5 5 5 2 HEAT repeats RasGEF_N_2 PF14663.1 KHN69052.1 - 0.0012 18.8 0.4 3.9 7.4 0.0 3.6 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.1 KHN69052.1 - 0.011 16.1 0.0 24 5.5 0.1 3.7 2 1 1 3 3 3 0 HEAT-like repeat DS PF01916.12 KHN69053.1 - 4.9e-110 367.3 0.1 5.9e-110 367.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase FtsJ PF01728.14 KHN69054.1 - 3.5e-54 183.5 0.1 4.1e-54 183.3 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Yos1 PF08571.5 KHN69055.1 - 2.6e-20 72.2 0.6 3e-20 72.0 0.4 1.0 1 0 0 1 1 1 1 Yos1-like Rod_cone_degen PF15201.1 KHN69055.1 - 0.035 13.9 0.1 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Progressive rod-cone degeneration Rad52_Rad22 PF04098.10 KHN69056.1 - 5e-54 182.2 0.2 6.4e-54 181.8 0.2 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ERp29 PF07749.7 KHN69056.1 - 0.035 14.7 1.7 4.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Got1 PF04178.7 KHN69057.1 - 4.3e-21 75.2 19.3 5.5e-21 74.8 13.1 1.3 1 1 0 1 1 1 1 Got1/Sft2-like family Sec61_beta PF03911.11 KHN69058.1 - 9.6e-05 22.1 5.8 9.6e-05 22.1 4.0 2.0 2 0 0 2 2 2 1 Sec61beta family TcpE PF12648.2 KHN69058.1 - 0.065 13.3 0.8 0.069 13.3 0.6 1.1 1 0 0 1 1 1 0 TcpE family DUF4229 PF14012.1 KHN69058.1 - 6.7 6.6 8.2 9.2 6.2 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Bac_surface_Ag PF01103.18 KHN69059.1 - 0.00024 20.6 0.8 0.15 11.4 0.4 3.0 2 1 0 2 2 2 2 Surface antigen SPC22 PF04573.7 KHN69060.1 - 2.9e-08 33.1 0.0 4.2e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Signal peptidase subunit Metallophos PF00149.23 KHN69061.1 - 4.7e-35 120.8 0.1 6.5e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KHN69061.1 - 0.0095 15.7 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain dCMP_cyt_deam_1 PF00383.17 KHN69062.1 - 0.00099 18.7 0.2 0.0017 17.9 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Ribosomal_L3 PF00297.17 KHN69063.1 - 2.1e-85 286.3 12.2 2.5e-85 286.0 8.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 zf-CSL PF05207.8 KHN69064.1 - 1.4e-22 78.9 0.5 1.9e-22 78.4 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 KHN69064.1 - 0.011 15.3 0.2 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KHN69064.1 - 0.018 14.6 0.2 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zf-CCCH PF00642.19 KHN69065.1 - 3.5e-05 23.3 0.0 3.5e-05 23.3 0.0 1.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Fcf2 PF08698.6 KHN69065.1 - 0.0034 17.3 2.2 0.0034 17.3 1.5 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Vasculin PF15337.1 KHN69065.1 - 0.015 15.7 0.8 0.015 15.7 0.5 2.5 2 1 0 2 2 2 0 Vascular protein family Vasculin-like 1 SID-1_RNA_chan PF13965.1 KHN69065.1 - 0.19 9.8 1.4 0.24 9.5 1.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Porph_ging PF09697.5 KHN69065.1 - 0.84 9.8 3.9 0.55 10.4 0.2 2.5 3 1 0 3 3 3 0 Protein of unknown function (Porph_ging) Ycf1 PF05758.7 KHN69065.1 - 2.6 5.6 11.8 0.4 8.3 0.1 2.0 2 0 0 2 2 2 0 Ycf1 Cyclin_N PF00134.18 KHN69066.1 - 3.1e-23 81.7 1.9 1e-22 80.0 0.7 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain IRS PF02174.12 KHN69066.1 - 0.098 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) E1_dh PF00676.15 KHN69067.1 - 4.8e-72 242.2 0.7 6.1e-72 241.8 0.5 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KHN69067.1 - 0.00035 20.1 0.4 0.00064 19.3 0.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 KHN69067.1 - 0.00041 19.3 0.1 0.0026 16.7 0.0 2.1 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 KHN69067.1 - 0.007 15.2 0.1 0.015 14.1 0.0 1.5 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Lant_dehyd_C PF04738.8 KHN69068.1 - 0.054 11.7 0.0 0.096 10.9 0.0 1.4 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus HSCB_C PF07743.8 KHN69068.1 - 0.13 12.7 3.9 0.077 13.4 1.3 1.7 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF1240 PF06836.7 KHN69069.1 - 0.034 14.3 2.7 0.034 14.3 1.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1240) Tetraspannin PF00335.15 KHN69069.1 - 2.6 7.2 17.4 0.19 10.9 0.9 2.1 1 1 0 2 2 2 0 Tetraspanin family S1FA PF04689.8 KHN69069.1 - 5 7.0 5.3 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA Peptidase_C13 PF01650.13 KHN69070.1 - 1.7e-15 57.0 0.9 2.1e-15 56.7 0.7 1.1 1 0 0 1 1 1 1 Peptidase C13 family Band_3_cyto PF07565.8 KHN69071.1 - 0.056 12.9 3.9 0.085 12.3 2.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF948 PF06103.6 KHN69071.1 - 0.58 10.0 8.4 0.6 10.0 0.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 KHN69071.1 - 2.8 7.4 13.4 3 7.3 8.4 1.7 1 1 0 1 1 1 0 IncA protein SlyX PF04102.7 KHN69071.1 - 3.7 7.9 8.8 30 5.0 0.2 3.4 3 0 0 3 3 3 0 SlyX PAP_central PF04928.12 KHN69071.1 - 4.2 6.0 6.7 2.8 6.7 3.3 1.8 1 1 0 1 1 1 0 Poly(A) polymerase central domain Rifin_STEVOR PF02009.11 KHN69072.1 - 0.019 14.6 0.9 0.024 14.2 0.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family Use1 PF09753.4 KHN69072.1 - 0.03 13.7 2.7 0.067 12.6 1.8 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 PP1_inhibitor PF05361.7 KHN69072.1 - 0.04 13.5 0.7 0.058 13.0 0.5 1.2 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor RNA_binding PF01877.12 KHN69072.1 - 0.088 12.8 3.0 1.7 8.6 0.2 2.1 1 1 1 2 2 2 0 RNA binding SNARE PF05739.14 KHN69072.1 - 0.22 11.2 4.3 1.2 8.8 1.1 3.0 1 1 2 3 3 3 0 SNARE domain DUF912 PF06024.7 KHN69072.1 - 0.46 10.5 2.4 0.75 9.8 1.5 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RWD PF05773.17 KHN69073.1 - 0.0016 18.3 1.0 0.021 14.7 0.7 2.6 1 1 0 1 1 1 1 RWD domain Peptidase_M50 PF02163.17 KHN69074.1 - 0.026 13.4 0.0 0.059 12.3 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M50 DUF3981 PF13139.1 KHN69074.1 - 2.9 7.9 11.9 0.34 10.9 4.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3981) Mannosyl_trans2 PF04188.8 KHN69075.1 - 1.2e-35 123.3 33.7 2.4e-19 69.5 5.6 2.2 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) DUF3855 PF12967.2 KHN69075.1 - 0.088 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) DoxX PF07681.7 KHN69075.1 - 0.47 10.9 5.6 2.5 8.5 0.7 3.2 3 0 0 3 3 3 0 DoxX Lectin_leg-like PF03388.8 KHN69076.1 - 2e-10 40.1 0.2 3.1e-09 36.3 0.1 2.0 2 0 0 2 2 2 2 Legume-like lectin family SseC PF04888.7 KHN69077.1 - 0.073 12.4 0.6 0.19 11.0 0.4 1.7 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Spore_II_R PF09551.5 KHN69078.1 - 0.47 10.4 6.7 0.11 12.5 1.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) OmpH PF03938.9 KHN69078.1 - 1.1 9.1 8.1 0.13 12.1 2.0 2.1 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF4446 PF14584.1 KHN69078.1 - 1.7 8.4 7.2 0.26 11.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) NAP PF00956.13 KHN69079.1 - 1.8e-11 43.6 8.3 2.6e-11 43.1 5.8 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Ribul_P_3_epim PF00834.14 KHN69079.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ABC_tran PF00005.22 KHN69081.1 - 3.1e-23 82.6 0.0 5.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KHN69081.1 - 2.1e-13 50.9 0.1 2.1e-13 50.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.1 KHN69081.1 - 0.0013 17.8 0.1 0.016 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KHN69081.1 - 0.0032 16.7 1.8 0.041 13.1 0.9 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KHN69081.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KHN69081.1 - 0.028 14.3 0.1 0.33 10.9 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KHN69081.1 - 0.04 13.9 0.2 0.07 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KHN69081.1 - 0.045 13.8 0.4 0.18 11.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KHN69081.1 - 0.048 13.9 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KHN69081.1 - 0.053 12.4 0.1 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 KHN69081.1 - 0.073 12.2 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 KHN69081.1 - 0.091 13.5 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KHN69081.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.6 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.1 KHN69081.1 - 0.11 12.0 0.9 0.24 10.9 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 KHN69081.1 - 0.13 12.0 1.1 0.29 10.9 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KHN69081.1 - 0.15 11.4 1.4 0.22 10.8 0.4 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 KHN69081.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain zf-B_box PF00643.19 KHN69082.1 - 1.2e-09 37.8 16.1 4.2e-07 29.7 2.3 2.4 2 0 0 2 2 2 2 B-box zinc finger DUF2772 PF10970.3 KHN69082.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2772) TrkA_C PF02080.16 KHN69083.1 - 0.051 13.1 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-C domain DUF1947 PF09183.5 KHN69083.1 - 0.079 12.7 0.3 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) LSM PF01423.17 KHN69084.1 - 1.7e-10 40.2 0.3 2e-10 40.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain ubiquitin PF00240.18 KHN69085.1 - 0.027 13.8 0.0 0.071 12.5 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family zf-Di19 PF05605.7 KHN69085.1 - 0.11 12.6 0.4 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF3452 PF11934.3 KHN69086.1 - 0.018 14.3 0.0 0.018 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Clat_adaptor_s PF01217.15 KHN69087.1 - 7.3e-16 58.1 4.9 1.4e-15 57.2 3.4 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DNA_pol3_delta PF06144.8 KHN69087.1 - 0.074 12.5 0.1 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit EF-hand_7 PF13499.1 KHN69088.1 - 1.4e-12 47.5 6.8 1.7e-08 34.4 0.4 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KHN69088.1 - 9.1e-09 34.0 1.3 0.038 13.2 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 KHN69088.1 - 6.8e-08 31.7 1.0 0.077 12.9 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 KHN69088.1 - 0.00063 18.9 0.2 0.0047 16.2 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KHN69088.1 - 0.042 13.4 3.8 1.9 8.1 0.1 3.1 2 1 1 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KHN69088.1 - 0.079 12.9 0.1 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SCIMP PF15050.1 KHN69089.1 - 0.016 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 SCIMP protein DUF1749 PF08538.5 KHN69090.1 - 7.5e-21 74.3 0.7 1.6e-20 73.1 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KHN69090.1 - 9.1e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KHN69090.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KHN69090.1 - 0.00056 19.6 0.0 0.00083 19.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KHN69090.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase POP1 PF06978.6 KHN69091.1 - 8.2e-23 81.0 16.9 3.1e-14 53.0 3.7 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KHN69091.1 - 5.7e-09 35.7 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain WD40 PF00400.27 KHN69093.1 - 2.4e-07 30.3 1.6 0.013 15.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 KHN69094.1 - 8.4e-67 225.0 0.0 1e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69094.1 - 7.4e-43 146.4 0.0 8.7e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69094.1 - 6.4e-08 31.9 0.0 3.5e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KHN69094.1 - 0.00084 19.1 0.1 0.022 14.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KHN69094.1 - 0.012 14.9 0.2 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KHN69094.1 - 0.041 12.9 0.5 0.088 11.8 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMR_HSR1 PF01926.18 KHN69095.1 - 1.4e-16 60.4 0.1 2.4e-15 56.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KHN69095.1 - 7.2e-07 28.6 0.0 0.00086 18.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 KHN69095.1 - 0.00027 20.1 0.0 0.00057 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KHN69095.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 KHN69095.1 - 0.12 12.9 0.1 0.74 10.3 0.0 2.2 2 1 0 2 2 2 0 Miro-like protein V-ATPase_H_C PF11698.3 KHN69096.1 - 1.9e-18 66.4 0.9 1.9e-18 66.4 0.6 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 KHN69096.1 - 2.9e-10 39.7 2.4 6.8e-10 38.5 1.7 1.8 1 1 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 KHN69096.1 - 0.002 18.3 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 HEAT repeats Cyclin_N PF00134.18 KHN69097.1 - 1.3e-32 112.0 0.6 4e-32 110.4 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KHN69097.1 - 9e-19 67.5 0.0 1.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain MIF4G_like_2 PF09090.6 KHN69098.1 - 1.1e-07 31.4 0.0 2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G like Proteasome PF00227.21 KHN69099.1 - 8.4e-31 106.7 0.4 9.4e-31 106.5 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Melibiase PF02065.13 KHN69099.1 - 0.076 11.6 0.0 0.078 11.6 0.0 1.2 1 0 0 1 1 1 0 Melibiase Uteroglobin PF01099.12 KHN69099.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family MCM PF00493.18 KHN69100.1 - 1.4e-122 408.6 0.6 2e-122 408.1 0.4 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KHN69100.1 - 9e-10 39.0 0.0 1.8e-08 34.9 0.0 2.6 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KHN69100.1 - 4.8e-08 32.4 0.0 5e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KHN69100.1 - 0.0011 18.5 0.1 0.0041 16.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KHN69100.1 - 0.006 16.0 0.5 0.06 12.8 0.0 2.7 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_5 PF07728.9 KHN69100.1 - 0.024 14.3 0.0 0.094 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KHN69100.1 - 0.045 13.9 0.7 0.25 11.5 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) HemN_C PF06969.11 KHN69100.1 - 0.12 12.4 0.3 0.62 10.1 0.1 2.3 2 0 0 2 2 2 0 HemN C-terminal domain PIG-L PF02585.12 KHN69101.1 - 1.6e-19 70.6 0.0 2.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glycophorin_A PF01102.13 KHN69101.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A RNA_pol_Rpb6 PF01192.17 KHN69103.1 - 1.4e-16 60.0 0.0 2.8e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 ATP_synt_H PF05493.8 KHN69104.1 - 6.7e-08 32.4 2.0 7.5e-08 32.3 1.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit H YoqO PF14037.1 KHN69104.1 - 0.0045 17.0 1.1 0.0054 16.8 0.8 1.0 1 0 0 1 1 1 1 YoqO-like protein PGG PF13962.1 KHN69104.1 - 0.029 13.9 0.9 0.033 13.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function Intg_mem_TP0381 PF09529.5 KHN69104.1 - 0.069 12.3 1.4 0.074 12.2 1.0 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) FUSC-like PF12805.2 KHN69104.1 - 0.12 11.2 1.1 0.15 11.0 0.7 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS HIG_1_N PF04588.8 KHN69104.1 - 0.4 10.4 2.5 1.5 8.6 0.0 2.0 1 1 1 2 2 2 0 Hypoxia induced protein conserved region FeoB_N PF02421.13 KHN69105.1 - 0.0003 20.0 2.4 0.008 15.4 0.7 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP-synt_ab PF00006.20 KHN69105.1 - 0.076 12.5 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Adap_comp_sub PF00928.16 KHN69106.1 - 3.5e-08 32.8 4.5 5.3e-08 32.2 3.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_S19 PF00203.16 KHN69107.1 - 8.6e-18 63.7 0.0 1.4e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 KOW PF00467.24 KHN69109.1 - 4.8e-06 26.0 2.9 8.5e-06 25.2 2.0 1.4 1 0 0 1 1 1 1 KOW motif DUF2423 PF10338.4 KHN69109.1 - 0.029 14.3 1.3 0.075 13.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) RRM_1 PF00076.17 KHN69110.1 - 7.8e-15 54.2 1.3 1.1e-14 53.8 0.0 1.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69110.1 - 9.2e-14 51.1 0.1 3.3e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 KHN69110.1 - 1.7e-13 50.4 1.3 2.5e-13 49.9 0.9 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 KHN69110.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaB_2 PF07261.6 KHN69110.1 - 0.24 10.9 1.2 1.9 8.1 0.1 2.4 1 1 1 2 2 2 0 Replication initiation and membrane attachment HIT PF01230.18 KHN69111.1 - 1.9e-17 63.5 0.4 2.9e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KHN69111.1 - 7.1e-07 29.4 1.8 1.2e-06 28.7 1.2 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KHN69111.1 - 6.4e-05 22.5 0.4 9.1e-05 22.0 0.2 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Baculo_LEF5 PF04838.7 KHN69111.1 - 0.11 12.3 0.3 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 Rep_1 PF01446.12 KHN69111.1 - 0.16 11.2 2.2 1.1 8.5 0.4 2.1 1 1 1 2 2 2 0 Replication protein Nol1_Nop2_Fmu PF01189.12 KHN69112.1 - 2.5e-33 115.6 0.0 1e-30 107.1 0.0 2.1 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 KHN69112.1 - 0.00034 20.6 0.1 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Homez PF11569.3 KHN69112.1 - 0.0063 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Methyltransf_26 PF13659.1 KHN69112.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 KHN69112.1 - 0.05 13.1 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Histone PF00125.19 KHN69113.1 - 0.00029 20.8 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KHN69113.1 - 0.005 16.9 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID_20kDa PF03847.8 KHN69113.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KHN69113.1 - 0.016 15.2 0.1 0.044 13.8 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GAS PF13851.1 KHN69114.1 - 2.4 7.3 40.5 0.047 12.8 11.4 2.8 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 KHN69114.1 - 4.4 7.0 34.0 0.044 13.5 2.0 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3169 PF11368.3 KHN69115.1 - 0.0094 15.1 9.5 0.052 12.7 0.2 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3169) DUF2072 PF09845.4 KHN69115.1 - 0.096 12.6 7.8 2.4 8.0 1.8 2.4 2 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) ETRAMP PF09716.5 KHN69115.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.8 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF202 PF02656.10 KHN69115.1 - 0.2 11.8 1.2 3.9 7.7 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF3899 PF13038.1 KHN69115.1 - 0.4 10.8 4.9 21 5.3 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) DUF2951 PF11166.3 KHN69115.1 - 0.45 10.4 5.5 0.33 10.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) OppC_N PF12911.2 KHN69115.1 - 6.3 6.2 0.0 6.3 6.2 0.0 3.8 4 1 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Med26 PF08711.6 KHN69116.1 - 2.3e-13 49.4 0.1 4.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PDEase_I_N PF08499.7 KHN69116.1 - 0.015 15.1 0.6 1.3 9.0 0.1 2.7 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal GlutR_dimer PF00745.15 KHN69116.1 - 0.075 12.9 1.2 1.3 9.0 0.0 2.9 2 1 2 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain Swi3 PF07962.7 KHN69117.1 - 0.0087 15.6 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 Toxin_30 PF08117.6 KHN69118.1 - 0.44 10.6 0.2 0.44 10.6 0.1 2.5 3 0 0 3 3 3 0 Ptu family Pro_isomerase PF00160.16 KHN69119.1 - 7e-42 143.2 0.1 8.1e-42 143.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bacteriocin_IIi PF11758.3 KHN69119.1 - 0.13 11.9 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin tRNA-synt_1e PF01406.14 KHN69121.1 - 8.9e-116 386.2 4.0 1.6e-115 385.4 2.7 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KHN69121.1 - 2.9e-15 55.8 4.3 4.3e-09 35.5 0.2 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KHN69121.1 - 1e-05 23.7 1.7 0.00049 18.2 0.0 2.7 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 KHN69121.1 - 0.018 13.6 0.3 0.018 13.6 0.2 3.0 4 1 1 5 5 5 0 tRNA synthetases class I (E and Q), catalytic domain DUF1447 PF07288.6 KHN69121.1 - 0.19 11.5 4.6 3.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1447) YodL PF14191.1 KHN69123.1 - 0.11 13.0 1.4 0.45 11.0 0.3 2.1 1 1 1 2 2 2 0 YodL-like HJURP_C PF12347.3 KHN69123.1 - 0.19 11.2 3.1 0.4 10.2 0.1 2.4 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat RRM_6 PF14259.1 KHN69124.1 - 2.1e-38 130.1 2.1 2.6e-15 56.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN69124.1 - 5.6e-37 125.2 1.5 2.4e-13 49.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69124.1 - 2.8e-16 59.0 1.6 0.00083 19.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAS PF03059.11 KHN69124.1 - 0.051 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein YhhN PF07947.9 KHN69125.1 - 1.5 8.1 16.3 0.036 13.4 3.5 2.4 2 1 0 2 2 2 0 YhhN-like protein DUF202 PF02656.10 KHN69125.1 - 1.9 8.7 15.2 1.7 8.9 0.7 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF202) TctB PF07331.6 KHN69125.1 - 2.2 7.9 13.6 1.2 8.7 5.5 2.7 1 1 2 3 3 3 0 Tripartite tricarboxylate transporter TctB family LSM PF01423.17 KHN69126.1 - 2.8e-14 52.4 0.3 3.1e-14 52.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 KHN69126.1 - 0.0042 16.8 0.1 0.0062 16.3 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 KHN69126.1 - 0.0082 16.0 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain tRNA-synt_1d PF00750.14 KHN69127.1 - 9.8e-64 215.3 0.8 1.3e-63 214.9 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KHN69127.1 - 2.3e-23 82.4 0.0 7.4e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain zf-C2H2 PF00096.21 KHN69128.1 - 3e-08 33.5 14.9 0.00091 19.4 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KHN69128.1 - 1.6e-07 31.1 11.5 0.0029 17.8 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KHN69128.1 - 7e-06 26.0 3.6 7e-06 26.0 2.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain CHORD PF04968.7 KHN69128.1 - 0.36 11.0 7.0 8.8 6.6 0.2 3.7 3 1 1 4 4 4 0 CHORD DUF572 PF04502.8 KHN69129.1 - 4.3e-28 98.4 0.2 5.3e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 KHN69129.1 - 0.057 12.9 0.2 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.7 KHN69129.1 - 0.11 11.7 1.0 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Benyvirus_14KDa PF07255.6 KHN69129.1 - 0.87 9.4 4.6 15 5.4 0.0 2.7 1 1 1 3 3 3 0 Benyvirus 14KDa protein DUF2118 PF09891.4 KHN69131.1 - 0.045 13.4 0.2 0.085 12.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) YrhK PF14145.1 KHN69131.1 - 0.11 12.1 1.2 0.13 11.9 0.1 1.6 2 0 0 2 2 2 0 YrhK-like protein FecCD PF01032.13 KHN69131.1 - 0.26 10.0 1.4 1.6 7.4 0.1 2.0 2 0 0 2 2 2 0 FecCD transport family RINT1_TIP1 PF04437.8 KHN69132.1 - 1.1e-11 44.0 0.2 3.1e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF1947 PF09183.5 KHN69132.1 - 0.25 11.1 6.3 0.37 10.5 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1947) Sec20 PF03908.8 KHN69132.1 - 0.28 10.8 5.5 0.23 11.1 2.4 2.0 2 0 0 2 2 2 0 Sec20 Ribosomal_L18ae PF01775.12 KHN69133.1 - 1.4e-34 118.6 0.1 1.7e-34 118.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain HEAT_2 PF13646.1 KHN69134.1 - 5.1e-05 23.4 0.0 0.00054 20.1 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.2 KHN69134.1 - 0.00058 19.7 6.5 0.088 12.6 0.3 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF1442 PF07279.6 KHN69134.1 - 0.077 12.0 0.3 0.15 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) HEAT_EZ PF13513.1 KHN69134.1 - 0.19 12.2 0.0 1 9.9 0.0 2.3 2 0 0 2 2 2 0 HEAT-like repeat PLAC PF08686.6 KHN69134.1 - 1.9 8.8 7.8 0.45 10.8 0.1 3.7 3 0 0 3 3 3 0 PLAC (protease and lacunin) domain DNA_primase_S PF01896.14 KHN69136.1 - 6.6e-36 123.2 1.0 9.3e-36 122.7 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit EamA PF00892.15 KHN69137.1 - 0.01 15.8 28.1 0.13 12.2 11.4 2.6 2 1 0 2 2 2 0 EamA-like transporter family TPT PF03151.11 KHN69137.1 - 0.13 11.9 24.1 0.061 12.9 8.2 3.2 2 1 0 2 2 2 0 Triose-phosphate Transporter family TMEM238 PF15125.1 KHN69137.1 - 7.2 6.6 7.8 12 5.8 0.3 3.2 2 1 1 3 3 3 0 TMEM238 protein family RNA_pol_Rbc25 PF08292.7 KHN69138.1 - 5.1e-15 55.7 3.5 3.7e-13 49.7 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KHN69138.1 - 3.8e-06 26.9 0.1 6.5e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Peptidase_C70 PF12385.3 KHN69138.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Tubulin PF00091.20 KHN69140.1 - 2.6e-67 226.7 0.0 8.1e-67 225.1 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KHN69140.1 - 1.6e-16 60.4 0.0 2.9e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KHN69140.1 - 6.3e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KHN69140.1 - 0.00011 22.2 0.1 0.00053 20.0 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Clat_adaptor_s PF01217.15 KHN69141.1 - 0.085 12.5 2.6 0.15 11.7 1.8 1.4 1 1 0 1 1 1 0 Clathrin adaptor complex small chain Rer1 PF03248.8 KHN69143.1 - 3.5e-45 153.7 8.5 3.8e-45 153.6 5.9 1.0 1 0 0 1 1 1 1 Rer1 family UPF0104 PF03706.8 KHN69143.1 - 0.03 13.6 2.2 0.15 11.2 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) DUF2809 PF10990.3 KHN69143.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2809) PRRSV_2b PF07069.6 KHN69143.1 - 0.97 9.7 3.4 6.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b DUF4010 PF13194.1 KHN69145.1 - 0.037 13.3 0.3 0.05 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Ras PF00071.17 KHN69146.1 - 1.5e-56 190.2 1.1 1.8e-56 190.0 0.8 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN69146.1 - 1.4e-18 67.5 0.1 2.6e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN69146.1 - 1.7e-14 53.4 0.1 2e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN69146.1 - 2.3e-07 30.1 0.1 2.8e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KHN69146.1 - 5.7e-06 26.2 0.0 1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KHN69146.1 - 0.00026 20.4 0.0 0.00058 19.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arg_tRNA_synt_N PF03485.11 KHN69146.1 - 0.022 15.2 0.2 0.043 14.3 0.2 1.4 1 1 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF3787 PF12655.2 KHN69146.1 - 0.046 13.4 0.5 6.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) DUF440 PF04269.7 KHN69146.1 - 0.048 13.6 0.1 0.09 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF440 SRPRB PF09439.5 KHN69146.1 - 0.072 12.3 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 KHN69146.1 - 0.087 12.7 0.1 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KHN69146.1 - 0.089 12.6 0.6 0.17 11.6 0.4 1.6 1 1 0 1 1 1 0 Dynamin family ParA PF10609.4 KHN69147.1 - 7.3e-24 83.4 0.0 1.4e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KHN69147.1 - 1.2e-14 54.2 0.0 2.2e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KHN69147.1 - 3.8e-08 33.4 0.3 2.5e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KHN69147.1 - 4.6e-07 29.1 1.5 5.6e-06 25.6 0.7 2.6 3 1 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 KHN69147.1 - 0.0016 17.5 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 KHN69147.1 - 0.0045 16.2 0.1 0.0078 15.4 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 KHN69147.1 - 0.038 13.3 0.6 0.16 11.2 0.3 1.8 2 0 0 2 2 2 0 YhjQ protein AAA_26 PF13500.1 KHN69147.1 - 0.092 12.3 0.1 14 5.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain ERCC4 PF02732.10 KHN69148.1 - 2.1e-13 50.2 1.0 4.1e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 ERCC4 domain RNA_pol_Rpb4 PF03874.11 KHN69149.1 - 1.3e-15 57.4 0.1 2e-15 56.8 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 OGG_N PF07934.7 KHN69150.1 - 5.1e-14 52.2 0.0 1.1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KHN69150.1 - 5.6e-05 23.3 0.0 0.00038 20.7 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KHN69150.1 - 0.018 14.7 0.2 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2179 PF10035.4 KHN69151.1 - 0.49 10.0 3.2 40 3.9 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2179) DUF3671 PF12420.3 KHN69152.1 - 0.01 15.8 1.8 0.028 14.3 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function Solute_trans_a PF03619.11 KHN69152.1 - 0.067 12.4 3.7 0.048 12.9 0.2 2.2 2 1 0 2 2 2 0 Organic solute transporter Ostalpha SRP19 PF01922.12 KHN69153.1 - 2.4e-19 69.7 0.0 3.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Na_Ca_ex PF01699.19 KHN69154.1 - 2.4e-06 27.2 7.3 2.4e-06 27.2 5.1 3.1 2 1 1 3 3 3 1 Sodium/calcium exchanger protein Cytochrom_B558a PF05038.8 KHN69154.1 - 5.3 6.6 6.3 0.32 10.5 0.3 1.9 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Ribosomal_L4 PF00573.17 KHN69155.1 - 4.7e-37 127.2 1.1 6e-37 126.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KHN69155.1 - 0.012 15.4 1.4 0.076 12.9 0.0 2.6 3 0 0 3 3 3 0 60S ribosomal protein L4 C-terminal domain TPR_11 PF13414.1 KHN69156.1 - 3.5e-08 32.9 3.0 9.9e-05 21.9 0.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 KHN69156.1 - 1.7e-06 27.3 1.5 0.25 11.2 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KHN69156.1 - 3e-06 26.7 6.5 0.1 12.5 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 KHN69156.1 - 5.1e-05 22.6 8.4 0.031 13.8 0.0 4.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69156.1 - 0.00026 20.8 0.1 3.1 7.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat KorB PF08535.5 KHN69156.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.8 1 0 0 1 1 1 0 KorB domain TPR_17 PF13431.1 KHN69156.1 - 0.034 14.3 0.6 0.56 10.5 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat CAF1 PF04857.15 KHN69157.1 - 2.5e-63 213.8 0.6 6e-63 212.6 0.4 1.5 1 1 0 1 1 1 1 CAF1 family ribonuclease Adeno_knob PF00541.12 KHN69157.1 - 0.074 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) UQ_con PF00179.21 KHN69158.1 - 2.1e-35 121.1 0.0 2.6e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KHN69158.1 - 0.0022 17.6 0.9 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 UEV domain RS4NT PF08071.7 KHN69159.1 - 1e-16 60.5 2.7 2.1e-16 59.4 1.9 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain Ribosomal_S4e PF00900.15 KHN69159.1 - 3.2e-16 58.7 0.0 5.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal family S4e S4 PF01479.20 KHN69159.1 - 0.00068 19.0 0.1 0.0018 17.6 0.0 1.8 2 0 0 2 2 2 1 S4 domain HhH-GPD PF00730.20 KHN69160.1 - 1.4e-19 70.3 0.0 2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KHN69160.1 - 0.00056 19.4 0.1 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2400 PF09674.5 KHN69160.1 - 0.075 12.7 0.5 0.33 10.5 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) DUF3136 PF11334.3 KHN69160.1 - 0.1 12.0 0.1 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) EndIII_4Fe-2S PF10576.4 KHN69160.1 - 0.94 9.7 9.7 0.22 11.7 4.3 1.8 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Kinesin PF00225.18 KHN69161.1 - 1.6e-83 280.1 1.9 2.2e-83 279.7 1.3 1.1 1 0 0 1 1 1 1 Kinesin motor domain DivIC PF04977.10 KHN69161.1 - 0.019 14.4 0.2 0.048 13.1 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator IF4E PF01652.13 KHN69162.1 - 4.3e-30 104.4 1.0 5e-30 104.1 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cauli_DNA-bind PF03310.8 KHN69163.1 - 0.21 11.4 2.7 0.45 10.3 1.9 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein cNMP_binding PF00027.24 KHN69165.1 - 8e-17 60.8 0.2 3.5e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain ORC6 PF05460.8 KHN69166.1 - 0.074 12.1 0.6 0.08 12.0 0.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Snurportin1 PF11538.3 KHN69166.1 - 0.09 12.5 0.8 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Snurportin1 Rad21_Rec8 PF04824.11 KHN69167.1 - 9.7e-06 24.6 0.0 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KHN69167.1 - 0.0017 17.9 0.5 0.01 15.4 0.0 2.3 2 2 1 3 3 3 1 ScpA/B protein Sbi-IV PF11621.3 KHN69167.1 - 0.059 13.5 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI HSF_DNA-bind PF00447.12 KHN69168.1 - 1.1e-31 109.0 1.0 1.8e-31 108.3 0.7 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Tyr-DNA_phospho PF06087.7 KHN69168.1 - 0.058 12.0 0.1 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase GLTSCR1 PF15249.1 KHN69169.1 - 0.00074 19.5 0.5 0.0017 18.4 0.3 1.7 1 1 0 1 1 1 1 Glioma tumor suppressor candidate region tRNA_deacylase PF04414.7 KHN69169.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase PHF5 PF03660.9 KHN69170.1 - 3.1e-16 59.3 14.4 3.5e-16 59.1 10.0 1.0 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.24 KHN69170.1 - 4.9 6.9 20.5 4.1 7.1 9.3 2.3 1 1 1 2 2 2 0 PHD-finger Kazal_2 PF07648.10 KHN69170.1 - 9.3 6.2 11.7 4.3 7.3 2.0 2.9 3 1 0 3 3 3 0 Kazal-type serine protease inhibitor domain Spc7 PF08317.6 KHN69173.1 - 4.2e-11 42.0 14.1 4.2e-11 42.0 9.8 2.4 3 0 0 3 3 3 1 Spc7 kinetochore protein PEP-utilisers_N PF05524.8 KHN69173.1 - 0.43 10.3 4.9 0.58 9.9 1.3 2.5 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Ndc1_Nup PF09531.5 KHN69174.1 - 0.00081 17.9 0.8 0.00081 17.9 0.5 1.3 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup SPATA24 PF15175.1 KHN69174.1 - 0.0048 16.6 1.4 0.006 16.2 0.9 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 FANCI_S3 PF14677.1 KHN69174.1 - 0.012 15.0 0.2 0.014 14.8 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 DUF1447 PF07288.6 KHN69174.1 - 0.034 13.9 0.1 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) FANCI_S2 PF14676.1 KHN69174.1 - 0.07 13.0 0.3 0.15 11.9 0.1 1.6 1 1 1 2 2 2 0 FANCI solenoid 2 Ribosomal_S25 PF03297.10 KHN69176.1 - 2.6e-16 59.5 5.6 3.3e-16 59.2 3.9 1.1 1 0 0 1 1 1 1 S25 ribosomal protein ADP_PFK_GK PF04587.10 KHN69176.1 - 0.026 12.7 0.6 0.032 12.4 0.4 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Ribosomal_S13_N PF08069.7 KHN69178.1 - 3e-16 58.9 0.1 1.1e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KHN69178.1 - 1.5e-13 50.2 0.1 2.1e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S25 PF03297.10 KHN69179.1 - 2.6e-16 59.5 5.6 3.3e-16 59.2 3.9 1.1 1 0 0 1 1 1 1 S25 ribosomal protein ADP_PFK_GK PF04587.10 KHN69179.1 - 0.026 12.7 0.6 0.032 12.4 0.4 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DEAD PF00270.24 KHN69180.1 - 1e-41 142.2 0.0 2.9e-41 140.7 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69180.1 - 7.9e-24 83.3 0.4 2.4e-23 81.8 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69180.1 - 0.0064 16.3 0.0 0.024 14.4 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KHN69180.1 - 0.056 13.0 0.0 0.55 9.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain Radical_SAM PF04055.16 KHN69181.1 - 7.5e-16 58.7 0.2 1.6e-14 54.4 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KHN69181.1 - 5.2e-12 45.6 0.2 2e-11 43.7 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KHN69181.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 KHN69181.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KHN69181.1 - 0.071 13.2 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Adaptin_N PF01602.15 KHN69182.1 - 4e-24 84.8 0.3 4e-24 84.8 0.2 2.1 2 1 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KHN69182.1 - 5.1e-16 58.6 0.0 1.3e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KHN69182.1 - 4.4e-10 39.3 0.5 1.3e-09 37.8 0.1 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KHN69182.1 - 7e-05 23.0 0.0 0.0055 16.9 0.0 3.0 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 KHN69182.1 - 0.0037 17.2 0.0 0.018 15.0 0.0 2.3 1 0 0 1 1 1 1 HEAT repeat WD40 PF00400.27 KHN69183.1 - 3.1e-32 109.2 8.0 4e-10 39.1 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KHN69183.1 - 0.0044 15.2 0.2 0.83 7.7 0.0 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KHN69183.1 - 0.0086 16.3 0.3 9.8 6.6 0.0 3.7 4 0 0 4 4 4 2 PQQ-like domain eIF2A PF08662.6 KHN69183.1 - 0.0092 15.7 0.1 0.032 13.9 0.1 1.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ThiC-associated PF13667.1 KHN69183.1 - 0.087 12.3 1.9 1.3 8.6 0.0 2.9 3 0 0 3 3 3 0 ThiC-associated domain DEAD_2 PF06733.10 KHN69184.1 - 6.3e-41 139.6 3.9 1.2e-40 138.7 2.7 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KHN69184.1 - 1.2e-31 109.8 0.1 2.7e-31 108.7 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 KHN69184.1 - 0.00024 21.0 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.24 KHN69184.1 - 0.0048 16.4 0.0 0.15 11.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KHN69184.1 - 0.0053 16.8 0.1 0.33 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KHN69184.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Brix PF04427.13 KHN69185.1 - 5.2e-23 81.6 1.0 6.4e-23 81.4 0.7 1.1 1 0 0 1 1 1 1 Brix domain HGTP_anticodon PF03129.15 KHN69185.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Anticodon binding domain DUF2729 PF10870.3 KHN69186.1 - 0.95 9.2 4.1 1.9 8.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2729) adh_short PF00106.20 KHN69187.1 - 1.5e-12 47.7 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KHN69187.1 - 0.0002 21.1 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 KHN69187.1 - 0.0018 17.6 0.0 0.0061 15.9 0.0 1.8 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DFP PF04127.10 KHN69187.1 - 0.0025 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 KHN69187.1 - 0.0032 16.3 0.1 0.0041 16.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 KHN69187.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3315 PF11776.3 KHN69187.1 - 0.018 14.5 0.1 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) Epimerase PF01370.16 KHN69187.1 - 0.022 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DAO PF01266.19 KHN69187.1 - 0.061 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UPF0728 PF15092.1 KHN69187.1 - 0.067 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 SBF2 PF12335.3 KHN69187.1 - 0.077 12.3 0.3 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Myotubularin protein ApbA PF02558.11 KHN69187.1 - 0.092 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KHN69187.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding Ribosomal_L14 PF00238.14 KHN69188.1 - 1.3e-39 134.6 0.0 1.6e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Trm112p PF03966.11 KHN69190.1 - 3.9e-08 33.5 0.0 1.1e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Trm112p-like protein Methyltransf_13 PF08421.6 KHN69190.1 - 0.064 12.7 2.9 0.99 8.9 0.2 2.6 2 1 0 2 2 2 0 Putative zinc binding domain zf-C2H2_3 PF13878.1 KHN69190.1 - 0.12 12.0 0.7 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO WD40 PF00400.27 KHN69191.1 - 1.7e-14 53.0 3.2 1.9e-06 27.4 0.0 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Bromodomain PF00439.20 KHN69191.1 - 0.0003 20.6 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain RNase_P_p30 PF01876.11 KHN69192.1 - 8.1e-26 90.0 0.0 1.2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 RNase_P_p30 PF01876.11 KHN69193.1 - 3e-19 68.7 0.1 3.9e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Dockerin_1 PF00404.13 KHN69193.1 - 0.068 12.8 2.1 0.67 9.7 0.0 2.6 2 0 0 2 2 2 0 Dockerin type I repeat CDtoxinA PF03498.9 KHN69198.1 - 0.076 12.3 0.0 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family WD40 PF00400.27 KHN69199.1 - 2e-40 135.2 17.3 9.1e-10 38.0 0.2 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KHN69199.1 - 6.1e-40 137.3 0.4 2.2e-38 132.2 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region Nup160 PF11715.3 KHN69199.1 - 0.0039 15.3 0.3 0.56 8.2 0.1 3.5 3 1 1 4 4 4 1 Nucleoporin Nup120/160 TPR_1 PF00515.23 KHN69199.1 - 0.03 13.9 0.8 7.1 6.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 KHN69199.1 - 0.055 13.0 0.1 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.12 KHN69199.1 - 0.94 9.5 5.2 12 6.0 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 KHN69200.1 - 2.7e-15 55.5 0.4 2.4e-06 27.1 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KHN69200.1 - 0.022 15.0 0.6 8.9 6.7 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain Lactonase PF10282.4 KHN69200.1 - 0.095 11.7 0.0 0.26 10.3 0.0 1.8 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller MMR_HSR1 PF01926.18 KHN69201.1 - 3.4e-19 68.9 0.0 7.1e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KHN69201.1 - 2.1e-18 65.9 0.0 4.7e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KHN69201.1 - 3.2e-11 42.7 0.0 5.7e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KHN69201.1 - 0.0069 15.1 0.1 0.11 11.2 0.0 2.5 2 1 0 2 2 2 1 ArgK protein Dynamin_N PF00350.18 KHN69201.1 - 0.0075 16.1 0.2 1.3 8.8 0.0 2.5 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 KHN69201.1 - 0.0086 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KHN69201.1 - 0.021 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_22 PF13401.1 KHN69201.1 - 0.021 14.9 0.0 0.58 10.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 KHN69201.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KHN69201.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KHN69201.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Prenyltrans PF00432.16 KHN69203.1 - 4e-45 151.0 7.4 7.2e-13 47.8 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KHN69203.1 - 2.9e-35 121.0 0.1 1.9e-11 44.3 0.1 3.4 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KHN69203.1 - 2.2e-12 46.9 0.0 3.5e-06 26.9 0.0 3.7 1 1 2 3 3 3 3 Prenyltransferase-like TLC PF03219.9 KHN69204.1 - 7e-51 173.2 33.5 8.5e-51 172.9 23.2 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF2244 PF10003.4 KHN69205.1 - 1.3 8.3 3.9 2.1 7.6 2.7 1.4 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) TFIIS_C PF01096.13 KHN69206.1 - 1.6e-16 59.6 5.3 6.1e-16 57.7 1.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF3797 PF12677.2 KHN69206.1 - 0.0023 17.5 1.8 0.0023 17.5 1.2 2.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3797) zf-RING_4 PF14570.1 KHN69206.1 - 0.0026 17.2 6.4 0.22 11.1 0.0 3.3 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain DUF866 PF05907.8 KHN69206.1 - 0.0065 15.9 2.6 0.0088 15.5 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) tRNA-synt_1f PF01921.13 KHN69206.1 - 0.007 15.0 3.0 0.097 11.3 0.5 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (K) Ogr_Delta PF04606.7 KHN69206.1 - 0.068 12.8 0.8 0.24 11.0 0.5 2.0 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.1 KHN69206.1 - 0.086 13.1 0.7 0.086 13.1 0.5 2.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-CSL PF05207.8 KHN69206.1 - 0.11 11.9 0.5 0.11 11.9 0.3 2.8 1 1 1 2 2 2 0 CSL zinc finger CpXC PF14353.1 KHN69206.1 - 0.12 12.3 4.6 0.22 11.4 3.2 1.5 1 1 0 1 1 1 0 CpXC protein Zn-ribbon_8 PF09723.5 KHN69206.1 - 0.28 11.1 6.2 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain CGGC PF08821.6 KHN69206.1 - 0.37 10.8 5.2 0.49 10.4 3.6 1.2 1 0 0 1 1 1 0 CGGC domain zf-C4pol PF14260.1 KHN69206.1 - 0.48 10.4 5.1 1.5 8.8 3.5 1.9 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta HypA PF01155.14 KHN69206.1 - 1 9.0 8.1 2 8.1 3.1 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF951 PF06107.6 KHN69206.1 - 1.6 8.3 4.7 1.3 8.5 0.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-TFIIB PF13453.1 KHN69206.1 - 2 7.6 6.0 0.45 9.7 0.7 2.3 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.2 KHN69206.1 - 2.7 7.9 8.5 20 5.1 3.7 2.8 1 1 0 1 1 1 0 Double zinc ribbon Mu-like_Com PF10122.4 KHN69206.1 - 4.8 6.3 7.7 17 4.5 0.0 3.5 1 1 2 3 3 3 0 Mu-like prophage protein Com TPR_2 PF07719.12 KHN69207.1 - 5e-13 47.8 0.6 0.45 10.5 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69207.1 - 5.4e-12 45.4 1.0 0.19 11.7 0.0 5.8 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 KHN69207.1 - 1.8e-11 43.5 4.3 0.00028 20.4 0.1 4.5 5 1 1 6 6 6 4 TPR repeat TPR_1 PF00515.23 KHN69207.1 - 5.6e-11 41.5 8.7 0.013 15.1 0.1 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 KHN69207.1 - 3.1e-10 40.4 0.0 4.3 8.1 0.0 5.7 3 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KHN69207.1 - 1e-09 37.4 14.3 0.019 14.7 0.1 6.7 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 KHN69207.1 - 8.1e-08 32.2 0.5 0.056 13.5 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KHN69207.1 - 1.2e-07 31.7 0.5 0.79 10.3 0.0 6.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 KHN69207.1 - 5.9e-05 23.3 0.0 0.34 11.2 0.0 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KHN69207.1 - 0.0016 18.4 0.2 7.7 6.9 0.0 5.8 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KHN69207.1 - 0.0019 17.8 0.8 1.8 8.5 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 KHN69207.1 - 0.0025 18.2 0.0 16 6.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.11 KHN69208.1 - 1.4e-31 109.6 24.2 1.9e-31 109.1 16.8 1.2 1 0 0 1 1 1 1 TLC domain Wzy_C PF04932.10 KHN69208.1 - 0.018 14.8 7.6 0.029 14.1 3.5 2.2 2 0 0 2 2 2 0 O-Antigen ligase Glutaredoxin PF00462.19 KHN69209.1 - 3.2e-10 39.8 0.1 4.3e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 KHN69209.1 - 0.00012 22.2 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KHN69209.1 - 0.073 13.0 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GATA PF00320.22 KHN69210.1 - 4.2e-17 61.1 4.3 7.3e-17 60.4 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 KHN69210.1 - 0.038 13.3 0.8 0.13 11.5 0.5 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding RRN7 PF11781.3 KHN69210.1 - 0.16 11.5 1.4 0.38 10.2 1.0 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_2 PF13639.1 KHN69211.1 - 8.1e-15 54.3 8.3 1.4e-14 53.6 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KHN69211.1 - 1.7e-08 34.3 8.4 2.8e-08 33.6 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KHN69211.1 - 5.3e-08 32.8 8.3 1.3e-07 31.6 5.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KHN69211.1 - 6e-07 29.0 6.4 9.8e-07 28.3 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KHN69211.1 - 1e-06 28.2 5.6 1.8e-06 27.5 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69211.1 - 3.5e-06 26.6 6.6 5.4e-06 26.0 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KHN69211.1 - 0.00099 18.9 5.0 0.0021 17.8 3.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KHN69211.1 - 0.0039 16.8 2.0 0.015 14.9 1.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KHN69211.1 - 0.023 14.5 3.4 0.057 13.3 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KHN69211.1 - 0.09 12.3 1.5 0.18 11.3 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.1 KHN69211.1 - 0.45 10.6 5.7 0.78 9.9 1.9 2.5 2 1 1 3 3 3 0 PHD-like zinc-binding domain PHD PF00628.24 KHN69211.1 - 0.46 10.2 7.5 1 9.0 5.2 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 KHN69211.1 - 0.71 9.5 5.5 1.4 8.5 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KHN69211.1 - 0.96 9.2 5.0 0.27 11.0 0.5 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 KHN69211.1 - 1.1 9.2 6.3 9.7 6.2 4.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KHN69211.1 - 1.3 9.1 5.9 2.9 8.0 4.1 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KHN69211.1 - 9.9 6.2 8.0 19 5.3 5.5 1.5 1 0 0 1 1 1 0 RING-like domain Syja_N PF02383.13 KHN69212.1 - 3.3e-50 170.6 0.6 5e-45 153.6 0.0 2.1 1 1 1 2 2 2 2 SacI homology domain Ten1 PF12658.2 KHN69213.1 - 0.064 13.0 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit zf-DHHC PF01529.15 KHN69214.1 - 4.4e-28 97.8 12.8 4.4e-28 97.8 8.9 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.20 KHN69214.1 - 0.01 15.9 1.6 0.01 15.9 1.1 2.5 2 1 0 2 2 2 0 Plexin repeat EXS PF03124.9 KHN69215.1 - 1.3e-53 182.2 29.1 2.5e-53 181.3 20.1 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KHN69215.1 - 2.7e-16 60.1 8.9 3.9e-09 36.6 4.4 2.3 1 1 1 2 2 2 2 SPX domain TRM PF02005.11 KHN69216.1 - 2.3e-93 313.1 3.4 2.9e-93 312.8 2.4 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 KHN69216.1 - 9.6e-07 28.5 2.0 9.6e-07 28.4 0.2 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KHN69216.1 - 5.4e-05 22.6 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KHN69216.1 - 0.0037 16.8 0.2 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein TerY-C PF15616.1 KHN69216.1 - 0.0044 16.9 1.6 0.014 15.3 1.1 1.8 1 0 0 1 1 1 1 TerY-C metal binding domain Methyltransf_18 PF12847.2 KHN69216.1 - 0.0048 17.4 0.0 0.0095 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KHN69216.1 - 0.035 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.20 KHN69218.1 - 7.4e-67 225.2 0.0 1.2e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69218.1 - 6e-34 117.2 0.0 8.4e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69218.1 - 3e-06 26.4 0.0 6.4e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KHN69218.1 - 0.0013 18.1 0.2 0.005 16.2 0.1 1.9 2 0 0 2 2 2 1 RIO1 family DUF1448 PF07289.6 KHN69218.1 - 0.018 13.9 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Kdo PF06293.9 KHN69218.1 - 0.052 12.5 0.1 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KHN69218.1 - 0.085 12.5 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-DHHC PF01529.15 KHN69220.1 - 1.1e-17 63.9 15.1 1.1e-17 63.9 10.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase C1_1 PF00130.17 KHN69220.1 - 0.094 12.4 8.0 0.17 11.6 5.5 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-A20 PF01754.11 KHN69220.1 - 4.4 6.9 8.8 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 A20-like zinc finger RRS1 PF04939.7 KHN69221.1 - 3e-21 75.5 2.1 4.5e-21 75.0 1.4 1.3 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PolyA_pol_RNAbd PF12627.2 KHN69221.1 - 0.14 11.7 0.2 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A vATP-synt_AC39 PF01992.11 KHN69222.1 - 1.9e-13 50.2 9.4 5.6e-12 45.4 6.5 2.0 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_5 PF13306.1 KHN69222.1 - 0.25 11.0 3.9 0.21 11.3 0.2 2.4 3 0 0 3 3 3 0 Leucine rich repeats (6 copies) DUF2203 PF09969.4 KHN69224.1 - 0.029 14.5 0.2 0.081 13.1 0.0 1.7 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Bromodomain PF00439.20 KHN69225.1 - 3.1e-20 71.8 0.5 4.4e-20 71.3 0.4 1.2 1 0 0 1 1 1 1 Bromodomain Tubulin-binding PF00418.14 KHN69225.1 - 0.13 12.0 0.5 0.27 10.9 0.4 1.5 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Ribosomal_L16 PF00252.13 KHN69226.1 - 2.8e-28 98.3 0.1 4.1e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Proteasome PF00227.21 KHN69227.1 - 2.6e-31 108.3 0.2 3e-31 108.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN69227.1 - 0.028 13.7 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature TPR_2 PF07719.12 KHN69228.1 - 0.00023 20.8 1.3 0.098 12.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KHN69228.1 - 0.0011 19.2 0.0 0.021 15.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69228.1 - 0.014 15.2 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3650 PF12368.3 KHN69228.1 - 0.025 14.0 0.1 0.067 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) TPR_14 PF13428.1 KHN69228.1 - 0.026 15.1 0.0 6.6 7.6 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SBDS PF01172.13 KHN69230.1 - 1.2e-19 69.8 0.3 2.5e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 KHN69230.1 - 2.6e-06 27.1 0.1 5.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain Semenogelin PF05474.6 KHN69230.1 - 0.002 16.5 1.9 0.0024 16.2 1.3 1.1 1 0 0 1 1 1 1 Semenogelin Translin PF01997.11 KHN69230.1 - 0.015 14.8 0.5 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Translin family DUF327 PF03885.8 KHN69230.1 - 0.046 13.5 2.0 0.65 9.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF327) B12-binding PF02310.14 KHN69230.1 - 0.081 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 KHN69231.1 - 2.2e-36 125.3 0.1 6.6e-36 123.7 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69231.1 - 3.1e-23 82.1 0.0 4.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.19 KHN69232.1 - 2e-06 27.3 2.7 3.8e-06 26.4 1.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KHN69232.1 - 0.13 12.2 2.9 0.3 11.1 2.0 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Bromodomain PF00439.20 KHN69233.1 - 5.1e-50 167.3 0.1 2.2e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain PspA_IM30 PF04012.7 KHN69233.1 - 0.021 14.1 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 PspA/IM30 family Spt4 PF06093.8 KHN69235.1 - 3.9e-30 103.5 0.2 4.9e-30 103.2 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DBR1 PF05011.8 KHN69236.1 - 0.036 13.9 0.4 0.044 13.6 0.3 1.2 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain CDC45 PF02724.9 KHN69236.1 - 0.31 9.0 7.2 0.35 8.8 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein MRP-L28 PF09812.4 KHN69236.1 - 2.8 7.7 11.1 1.3 8.8 6.3 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Cyclin_N PF00134.18 KHN69237.1 - 2.8e-06 26.9 1.9 8.4e-06 25.3 0.2 2.2 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 KHN69237.1 - 7.6e-06 26.4 2.0 2.1e-05 24.9 1.4 1.8 1 1 0 1 1 1 1 Cyclin PhoQ_Sensor PF08918.5 KHN69237.1 - 0.094 12.2 0.1 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 PhoQ Sensor ArfGap PF01412.13 KHN69238.1 - 1.5e-25 89.2 0.5 2.7e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Ricin_B_lectin PF00652.17 KHN69239.1 - 0.00069 19.6 0.1 0.002 18.1 0.1 1.7 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KHN69239.1 - 0.043 14.1 0.0 0.073 13.4 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Tau95 PF09734.4 KHN69242.1 - 1.5e-22 80.3 1.3 2.7e-21 76.2 0.9 2.0 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF1945 PF09178.5 KHN69242.1 - 0.075 12.9 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) Ribosomal_L6e PF01159.14 KHN69243.1 - 6.9e-09 35.9 0.2 0.00036 20.7 0.2 2.3 1 1 1 2 2 2 2 Ribosomal protein L6e Thr_synth_N PF14821.1 KHN69243.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Threonine synthase N terminus Pkinase PF00069.20 KHN69244.1 - 7.1e-57 192.5 0.0 8.3e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69244.1 - 1.2e-29 103.2 0.0 1.5e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69244.1 - 3e-09 36.2 0.0 5.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KHN69244.1 - 4.4e-05 22.6 0.0 7.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KHN69244.1 - 0.012 15.4 0.1 0.027 14.1 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KHN69244.1 - 0.02 13.7 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KHN69244.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Nse4_C PF08743.5 KHN69245.1 - 1.4e-13 50.6 0.1 4.4e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 Nse4 C-terminal TOM_sub5 PF15178.1 KHN69245.1 - 0.06 13.0 0.1 0.19 11.4 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM5 homolog TBCC PF07986.7 KHN69246.1 - 7.4e-10 38.2 11.6 8.1e-10 38.1 7.3 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C Coat_X PF07552.6 KHN69246.1 - 0.3 10.9 2.0 12 5.7 0.1 2.3 2 0 0 2 2 2 0 Spore Coat Protein X and V domain ATP_bind_4 PF01902.12 KHN69247.1 - 7e-42 143.2 0.3 2.6e-41 141.3 0.2 1.7 1 1 0 1 1 1 1 ATP-binding region tRNA_Me_trans PF03054.11 KHN69247.1 - 0.018 13.6 0.1 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase FpoO PF10621.4 KHN69247.1 - 0.043 13.8 0.1 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO G6PD_C PF02781.11 KHN69248.1 - 7.6e-32 110.3 0.4 4.1e-31 107.9 0.3 2.0 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KHN69248.1 - 2e-14 54.2 0.2 1.5e-13 51.3 0.1 2.3 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Proteasome PF00227.21 KHN69249.1 - 2.1e-44 151.0 1.2 2.6e-44 150.7 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit TFIIE_alpha PF02002.12 KHN69250.1 - 0.0017 17.8 7.8 0.23 10.9 0.1 4.0 4 0 0 4 4 4 2 TFIIE alpha subunit DUF3263 PF11662.3 KHN69250.1 - 0.051 13.0 0.2 0.76 9.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3263) AAA_5 PF07728.9 KHN69251.1 - 3.5e-108 357.2 0.1 1.7e-29 102.3 0.0 8.0 8 0 0 8 8 8 7 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KHN69251.1 - 4.2e-27 94.3 0.0 2.4e-09 36.8 0.0 5.2 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KHN69251.1 - 4.6e-21 75.4 2.0 3.7e-06 27.1 0.0 6.7 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KHN69251.1 - 7.7e-15 55.3 0.9 0.0018 18.2 0.0 4.8 4 0 0 4 4 4 4 AAA ATPase domain AAA_22 PF13401.1 KHN69251.1 - 4e-12 46.4 1.5 0.043 13.9 0.0 6.4 5 1 0 5 5 5 3 AAA domain Sigma54_activat PF00158.21 KHN69251.1 - 2.4e-11 43.4 0.0 0.097 12.1 0.0 5.8 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_18 PF13238.1 KHN69251.1 - 1.4e-08 35.0 10.1 0.038 14.2 0.0 6.3 5 0 0 5 5 4 2 AAA domain RNA_helicase PF00910.17 KHN69251.1 - 7.8e-08 32.4 0.5 2.1 8.5 0.0 5.5 5 0 0 5 5 4 2 RNA helicase ABC_tran PF00005.22 KHN69251.1 - 1.6e-07 31.7 5.1 1.2 9.4 0.0 5.0 4 0 0 4 4 4 3 ABC transporter Mg_chelatase PF01078.16 KHN69251.1 - 3.2e-07 29.7 2.6 0.18 10.9 0.0 6.4 7 1 1 8 8 7 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KHN69251.1 - 3.2e-07 29.6 5.2 0.14 11.2 0.1 5.5 4 3 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 KHN69251.1 - 5.8e-07 29.1 2.2 0.15 11.6 0.0 4.3 4 0 0 4 4 4 2 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 KHN69251.1 - 8.7e-07 27.9 4.4 0.014 14.1 0.0 4.1 4 0 0 4 4 4 2 TIP49 C-terminus AAA_17 PF13207.1 KHN69251.1 - 2.1e-06 28.5 0.3 1.3 9.8 0.0 6.1 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 KHN69251.1 - 2.4e-06 26.9 3.6 0.011 15.1 0.1 4.4 4 0 0 4 4 4 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KHN69251.1 - 2.6e-06 27.5 0.0 0.29 11.1 0.0 5.1 6 0 0 6 6 6 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KHN69251.1 - 7.8e-06 25.4 0.2 1.7 8.0 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_19 PF13245.1 KHN69251.1 - 1.3e-05 24.8 1.9 0.059 13.1 0.0 3.7 4 0 0 4 4 3 1 Part of AAA domain NACHT PF05729.7 KHN69251.1 - 1.4e-05 24.8 1.5 0.34 10.5 0.0 4.5 4 0 0 4 4 4 1 NACHT domain AAA_33 PF13671.1 KHN69251.1 - 4.2e-05 23.4 0.0 0.15 11.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 KHN69251.1 - 5.8e-05 22.1 0.5 0.53 9.1 0.0 4.2 4 0 0 4 4 4 1 Type II/IV secretion system protein ResIII PF04851.10 KHN69251.1 - 0.00016 21.5 0.2 0.79 9.5 0.0 4.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 KHN69251.1 - 0.00023 20.3 0.1 1.2 8.1 0.0 3.9 4 0 0 4 4 4 1 Zeta toxin Miro PF08477.8 KHN69251.1 - 0.00024 21.5 4.3 4.2 7.8 0.0 4.5 4 0 0 4 4 4 1 Miro-like protein AAA_25 PF13481.1 KHN69251.1 - 0.0003 20.2 0.1 13 5.1 0.0 4.4 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.8 KHN69251.1 - 0.00075 18.4 2.7 0.5 9.2 0.1 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 KHN69251.1 - 0.0021 17.6 0.3 6.6 6.2 0.0 4.1 5 0 0 5 5 4 0 AAA domain DEAD PF00270.24 KHN69251.1 - 0.0073 15.8 0.2 15 5.0 0.0 4.2 4 0 0 4 4 4 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.20 KHN69251.1 - 0.0079 15.7 0.1 15 4.9 0.0 3.6 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KHN69251.1 - 0.023 14.1 0.7 19 4.6 0.0 3.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family Ribosomal_L23 PF00276.15 KHN69252.1 - 7.2e-14 51.5 2.0 2.3e-13 49.8 1.4 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 Flavodoxin_3 PF12641.2 KHN69252.1 - 0.056 12.8 0.2 0.059 12.7 0.1 1.1 1 0 0 1 1 1 0 Flavodoxin domain DUF1687 PF07955.6 KHN69252.1 - 0.065 13.2 0.2 0.072 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Peptidase_M49 PF03571.10 KHN69252.1 - 0.072 11.1 0.2 0.075 11.0 0.1 1.0 1 0 0 1 1 1 0 Peptidase family M49 RRM_5 PF13893.1 KHN69252.1 - 0.12 12.2 0.1 3 7.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KHN69253.1 - 9.2e-76 254.4 0.0 1e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69253.1 - 2e-33 115.5 0.0 2.9e-33 115.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KHN69253.1 - 0.00053 19.1 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KHN69253.1 - 0.0009 18.2 0.0 0.0025 16.8 0.0 1.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KHN69253.1 - 0.0062 16.2 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KHN69253.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KHN69253.1 - 0.016 14.0 0.6 0.037 12.8 0.4 1.6 1 1 0 1 1 1 0 Seadornavirus VP7 DUF2600 PF10776.4 KHN69253.1 - 0.077 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) Arf PF00025.16 KHN69254.1 - 3e-43 147.0 0.0 3.5e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KHN69254.1 - 1.7e-10 40.4 0.0 2.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KHN69254.1 - 5e-09 35.6 0.0 7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KHN69254.1 - 8e-08 32.8 0.0 1.4e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KHN69254.1 - 4e-06 26.1 0.0 5.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KHN69254.1 - 4.2e-05 22.4 3.7 0.0001 21.1 0.6 2.4 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.12 KHN69254.1 - 0.00089 18.8 0.1 0.12 11.9 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KHN69254.1 - 0.0014 18.1 0.1 0.0074 15.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN69254.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 KHN69254.1 - 0.042 13.2 0.2 5.5 6.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KHN69254.1 - 0.045 14.0 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AP_endonuc_2 PF01261.19 KHN69254.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel AAA_17 PF13207.1 KHN69254.1 - 0.12 13.1 0.0 0.32 11.8 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KHN69254.1 - 0.13 12.1 0.0 0.5 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KHN69254.1 - 0.14 12.2 0.0 0.62 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain BUD22 PF09073.5 KHN69255.1 - 0.082 11.9 10.2 0.12 11.4 7.0 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.12 KHN69255.1 - 0.62 8.8 10.2 1.2 7.8 7.1 1.5 1 0 0 1 1 1 0 Presenilin CobT PF06213.7 KHN69255.1 - 6.8 5.7 14.0 11 5.0 9.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.20 KHN69256.1 - 4e-48 163.8 0.0 6.2e-47 159.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69256.1 - 1.2e-21 76.9 0.0 1.4e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KHN69256.1 - 6.4e-05 22.0 0.0 0.16 10.8 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KHN69256.1 - 0.0099 15.6 0.1 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KHN69256.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KHN69256.1 - 0.011 15.2 0.1 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 KHN69256.1 - 0.21 10.9 0.8 0.41 9.9 0.1 1.7 2 0 0 2 2 2 0 RIO1 family AAA PF00004.24 KHN69257.1 - 1.6e-46 157.8 0.0 3.1e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN69257.1 - 1.6e-08 34.3 0.1 5.1e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KHN69257.1 - 2.1e-08 34.2 0.2 5.6e-08 32.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KHN69257.1 - 7.6e-07 29.2 0.1 3.4e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KHN69257.1 - 9.4e-07 29.0 0.6 5.9e-05 23.2 0.4 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KHN69257.1 - 4.6e-05 22.4 0.0 7.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KHN69257.1 - 5.9e-05 22.8 0.1 0.00049 19.8 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 KHN69257.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN69257.1 - 0.00028 21.6 0.0 0.0007 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KHN69257.1 - 0.00033 19.7 0.0 0.00074 18.6 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KHN69257.1 - 0.00055 19.6 0.1 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KHN69257.1 - 0.00071 19.0 1.2 0.048 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KHN69257.1 - 0.00072 19.5 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN69257.1 - 0.0009 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KHN69257.1 - 0.00097 19.2 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 KHN69257.1 - 0.0018 17.9 0.0 0.0043 16.6 0.0 1.7 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KHN69257.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KHN69257.1 - 0.0028 17.2 0.0 0.008 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KHN69257.1 - 0.0031 16.6 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 KHN69257.1 - 0.0037 16.9 0.1 0.043 13.4 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase NACHT PF05729.7 KHN69257.1 - 0.0038 16.9 0.1 0.048 13.3 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 KHN69257.1 - 0.004 17.4 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KHN69257.1 - 0.0047 16.1 0.1 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KHN69257.1 - 0.0048 15.6 0.0 0.014 14.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 KHN69257.1 - 0.0063 16.0 0.1 0.088 12.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KHN69257.1 - 0.0065 15.9 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 KHN69257.1 - 0.0068 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KHN69257.1 - 0.0068 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KHN69257.1 - 0.0085 14.9 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KHN69257.1 - 0.031 14.5 0.1 0.1 12.9 0.0 2.0 2 1 0 2 2 1 0 ABC transporter Bac_DnaA PF00308.13 KHN69257.1 - 0.034 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 KHN69257.1 - 0.12 11.2 0.0 0.3 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 KHN69257.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF465 PF04325.8 KHN69257.1 - 0.4 10.4 3.0 0.92 9.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DUF1192 PF06698.6 KHN69259.1 - 0.0032 17.2 1.4 0.0068 16.1 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 KHN69259.1 - 0.05 13.4 12.3 0.076 12.8 8.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 KHN69259.1 - 0.11 11.7 2.9 0.14 11.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF651 PF04895.7 KHN69259.1 - 0.13 11.8 2.6 0.17 11.5 0.8 1.9 1 1 1 2 2 2 0 Archaeal protein of unknown function (DUF651) Flu_NS2 PF00601.14 KHN69259.1 - 0.33 11.1 5.0 0.41 10.8 2.2 2.1 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) SlyX PF04102.7 KHN69259.1 - 0.45 10.9 3.9 3.3 8.1 2.1 2.3 1 1 1 2 2 2 0 SlyX DivIC PF04977.10 KHN69259.1 - 0.53 9.8 4.4 2.3 7.7 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF2730 PF10805.3 KHN69259.1 - 0.64 9.7 5.8 10 5.8 3.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Uso1_p115_C PF04871.8 KHN69259.1 - 0.68 9.8 6.8 0.94 9.4 4.7 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.4 KHN69259.1 - 0.69 8.7 7.5 0.79 8.6 5.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 KHN69259.1 - 0.78 8.7 4.1 0.81 8.6 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.7 KHN69259.1 - 1 9.1 8.7 0.37 10.5 3.7 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIVA PF05103.8 KHN69259.1 - 1.7 8.7 8.7 13 5.8 6.7 2.1 2 1 0 2 2 2 0 DivIVA protein IncA PF04156.9 KHN69259.1 - 7.2 6.1 6.4 10 5.6 4.4 1.3 1 0 0 1 1 1 0 IncA protein Ribosomal_L11_N PF03946.9 KHN69260.1 - 4.4e-12 45.2 0.0 8.3e-12 44.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KHN69260.1 - 2.8e-10 40.1 0.7 4.6e-10 39.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Orbi_NS3 PF01616.11 KHN69260.1 - 0.014 14.4 0.3 0.017 14.0 0.2 1.1 1 0 0 1 1 1 0 Orbivirus NS3 RseC_MucC PF04246.7 KHN69264.1 - 0.044 13.3 1.1 0.11 12.0 0.3 1.9 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EMP24_GP25L PF01105.19 KHN69264.1 - 0.073 12.7 3.6 0.093 12.4 0.3 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1282 PF06930.7 KHN69264.1 - 0.33 10.6 14.5 0.51 9.9 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) Mpv17_PMP22 PF04117.7 KHN69264.1 - 0.51 10.0 6.4 0.26 10.9 1.3 2.3 2 0 0 2 2 2 0 Mpv17 / PMP22 family LRR_4 PF12799.2 KHN69267.1 - 3.4e-25 87.1 42.9 6.1e-08 32.1 0.8 7.4 5 2 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KHN69267.1 - 1.7e-10 40.4 35.9 6.4e-05 22.6 1.1 6.2 1 1 8 9 9 9 6 Leucine rich repeat LRR_1 PF00560.28 KHN69267.1 - 0.00016 21.2 41.4 7.1 7.0 0.0 12.0 10 2 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 KHN69267.1 - 3 8.1 39.0 13 6.1 0.0 11.3 7 4 5 12 12 12 0 Leucine Rich repeat ATG27 PF09451.5 KHN69268.1 - 0.00043 19.5 0.6 0.022 13.9 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein 27 Pex14_N PF04695.8 KHN69268.1 - 0.003 17.6 0.5 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2899 PF11449.3 KHN69268.1 - 0.016 14.4 5.4 0.084 12.0 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2899) DUF2956 PF11169.3 KHN69268.1 - 0.031 14.2 1.2 0.35 10.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Zip PF02535.17 KHN69268.1 - 0.11 11.5 4.8 0.22 10.4 3.3 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 KHN69268.1 - 0.12 10.3 4.7 0.17 9.9 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3464 PF11947.3 KHN69268.1 - 0.15 11.5 1.2 0.34 10.3 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) DUF805 PF05656.9 KHN69268.1 - 0.53 10.1 14.2 3.2 7.5 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF1129 PF06570.6 KHN69268.1 - 0.98 8.6 13.4 0.046 13.0 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1430 PF07242.6 KHN69268.1 - 2.8 8.0 17.8 3 7.9 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) U3_assoc_6 PF08640.6 KHN69269.1 - 7.6e-21 73.6 8.2 3.1e-20 71.7 4.6 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KHN69269.1 - 0.042 14.4 0.0 1.4 9.7 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3582 PF12122.3 KHN69269.1 - 0.13 12.2 0.2 1.6 8.7 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3582) RNA_pol_Rpb1_5 PF04998.12 KHN69270.1 - 1.9e-93 312.7 1.4 4.2e-93 311.6 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KHN69270.1 - 3.2e-70 237.0 0.9 8.4e-70 235.6 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KHN69270.1 - 3.8e-67 225.3 0.1 7.5e-67 224.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KHN69270.1 - 1.6e-32 112.3 0.0 4.8e-32 110.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KHN69270.1 - 1.2e-27 95.7 0.3 2.9e-27 94.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 NIF3 PF01784.13 KHN69271.1 - 5.1e-42 144.1 0.5 6.9e-42 143.6 0.4 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF2982 PF11201.3 KHN69271.1 - 0.067 12.5 0.1 6.7 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2982) DS PF01916.12 KHN69271.1 - 0.12 11.4 1.2 5.4 6.0 0.0 2.1 1 1 1 2 2 2 0 Deoxyhypusine synthase Ribosomal_60s PF00428.14 KHN69272.1 - 6.1e-11 42.5 4.1 8.1e-11 42.1 2.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein ASF1_hist_chap PF04729.8 KHN69274.1 - 2.6e-30 105.0 0.5 4.3e-30 104.3 0.1 1.5 2 0 0 2 2 2 1 ASF1 like histone chaperone TLP-20 PF06088.6 KHN69274.1 - 0.0032 17.1 0.4 0.0032 17.1 0.3 1.8 2 1 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Ycf1 PF05758.7 KHN69274.1 - 0.29 8.8 1.3 0.29 8.8 0.9 1.1 1 0 0 1 1 1 0 Ycf1 CENP-T PF15511.1 KHN69274.1 - 7.1 5.7 13.4 11 5.0 9.3 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SGL PF08450.7 KHN69276.1 - 0.023 14.0 0.1 28 3.9 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region WG_beta_rep PF14903.1 KHN69276.1 - 0.12 12.6 0.2 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 WG containing repeat His_Phos_2 PF00328.17 KHN69277.1 - 1.6e-26 93.4 0.0 5.3e-16 58.8 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-HC5HC2H PF13771.1 KHN69277.1 - 0.00088 19.3 1.4 0.0031 17.6 0.3 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KHN69277.1 - 0.065 13.2 2.3 0.15 12.0 0.2 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain AAA PF00004.24 KHN69278.1 - 7.9e-45 152.2 0.1 1.6e-44 151.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KHN69278.1 - 1.8e-08 34.4 0.0 4.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KHN69278.1 - 2.8e-07 29.8 0.0 5.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KHN69278.1 - 1.1e-06 28.7 0.2 0.0091 16.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 KHN69278.1 - 4.3e-06 26.4 1.4 1.7e-05 24.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KHN69278.1 - 2.5e-05 24.3 0.1 0.0029 17.6 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KHN69278.1 - 0.00039 21.2 0.3 0.0014 19.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KHN69278.1 - 0.00044 19.9 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KHN69278.1 - 0.00044 20.5 2.8 0.0068 16.7 0.1 3.2 2 1 2 4 4 4 1 AAA domain Mg_chelatase PF01078.16 KHN69278.1 - 0.0068 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KHN69278.1 - 0.0083 16.0 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KHN69278.1 - 0.0085 15.5 0.5 0.6 9.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KHN69278.1 - 0.0094 15.0 0.0 0.023 13.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KHN69278.1 - 0.0097 15.5 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KHN69278.1 - 0.011 14.6 0.1 0.023 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ResIII PF04851.10 KHN69278.1 - 0.012 15.4 0.0 0.7 9.7 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KHN69278.1 - 0.014 14.9 0.6 0.024 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KHN69278.1 - 0.017 14.7 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KHN69278.1 - 0.017 13.8 0.7 0.033 12.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 KHN69278.1 - 0.019 14.7 1.5 0.1 12.2 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 KHN69278.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 KHN69278.1 - 0.026 13.6 0.1 0.11 11.5 0.0 2.1 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 KHN69278.1 - 0.03 13.9 0.0 0.62 9.6 0.0 2.2 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KHN69278.1 - 0.042 14.0 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KHN69278.1 - 0.054 13.5 0.1 0.47 10.4 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 KHN69278.1 - 0.058 12.8 0.0 0.2 11.1 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 KHN69278.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KHN69278.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KHN69278.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nup35_RRM_2 PF14605.1 KHN69279.1 - 3e-07 30.0 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KHN69279.1 - 1.1e-05 25.0 0.0 0.00019 21.1 0.0 2.3 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif TFIIE_alpha PF02002.12 KHN69280.1 - 2.7e-17 62.1 8.2 2.7e-17 62.1 5.7 1.9 3 0 0 3 3 3 1 TFIIE alpha subunit Mitovir_RNA_pol PF05919.6 KHN69280.1 - 0.2 10.5 4.6 0.26 10.1 3.2 1.5 1 1 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase TFIIE-A_C-term PF11521.3 KHN69280.1 - 1.2 9.1 8.5 0.26 11.2 3.2 2.0 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Tim17 PF02466.14 KHN69282.1 - 1.8e-09 37.7 5.3 1.5e-07 31.5 0.9 2.2 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Sec8_exocyst PF04048.9 KHN69283.1 - 2.8e-08 33.4 1.4 7.1e-08 32.1 0.2 2.3 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain HSCB_C PF07743.8 KHN69283.1 - 0.0026 18.1 3.3 0.013 15.8 0.9 3.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain RasGEF PF00617.14 KHN69284.1 - 1.1e-06 28.5 0.2 1.9e-06 27.7 0.2 1.6 1 1 0 1 1 1 1 RasGEF domain LolA PF03548.10 KHN69284.1 - 0.038 13.6 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA UBA PF00627.26 KHN69286.1 - 5.7e-09 35.5 0.1 1.9e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 KHN69286.1 - 2.2e-05 23.7 0.8 4.1e-05 22.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KHN69286.1 - 0.011 16.0 0.6 0.021 15.0 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1542 PF07564.6 KHN69286.1 - 0.1 12.6 4.3 0.19 11.7 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Ribosomal_L32e PF01655.13 KHN69286.1 - 6.1 6.9 5.8 42 4.2 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein L32 Metalloenzyme PF01676.13 KHN69287.1 - 4.4e-08 32.8 0.9 8e-08 31.9 0.6 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KHN69287.1 - 1.4e-06 27.9 2.2 9e-06 25.2 1.4 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Nol1_Nop2_Fmu PF01189.12 KHN69288.1 - 8.8e-27 94.2 0.0 2e-26 93.0 0.0 1.6 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KHN69288.1 - 5.9e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KHN69288.1 - 0.00016 20.8 0.0 0.00049 19.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 KHN69288.1 - 0.0047 17.4 0.0 0.0084 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KHN69288.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.5 KHN69288.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KHN69288.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.13 KHN69288.1 - 0.11 12.0 0.6 0.26 10.7 0.1 1.8 2 0 0 2 2 2 0 DNA methylase zf-RING_2 PF13639.1 KHN69289.1 - 4.2e-14 52.0 11.1 6.6e-14 51.4 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KHN69289.1 - 4.8e-07 29.3 12.6 8.1e-07 28.6 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KHN69289.1 - 2.3e-06 27.6 11.0 5.4e-06 26.4 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KHN69289.1 - 2e-05 24.5 11.9 3.6e-05 23.7 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN69289.1 - 5.9e-05 22.6 10.7 9.4e-05 22.0 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69289.1 - 0.00067 19.3 11.4 0.0011 18.6 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KHN69289.1 - 0.0026 17.5 7.1 0.0077 16.0 4.9 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KHN69289.1 - 0.036 14.0 9.3 0.099 12.6 6.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 KHN69289.1 - 0.084 12.8 9.8 0.18 11.8 6.8 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 KHN69289.1 - 0.16 11.5 8.9 0.45 10.1 6.0 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KHN69289.1 - 0.19 11.3 4.4 0.34 10.4 3.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.2 KHN69289.1 - 0.45 10.5 12.0 1.1 9.3 8.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 KHN69289.1 - 1.1 9.1 8.1 3.2 7.7 5.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KHN69289.1 - 9.6 5.7 9.9 29 4.2 6.9 1.8 1 1 0 1 1 1 0 P-11 zinc finger RRM_1 PF00076.17 KHN69290.1 - 1.8e-25 88.3 2.1 1.1e-13 50.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69290.1 - 1.3e-22 79.4 0.6 3.5e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69290.1 - 7.8e-17 61.0 0.2 3e-10 39.9 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KHN69290.1 - 0.0027 17.5 0.2 0.83 9.5 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Peptidase_C50 PF03568.12 KHN69291.1 - 2.8e-52 177.6 0.9 7.1e-52 176.3 0.6 1.5 1 1 0 1 1 1 1 Peptidase family C50 DUF167 PF02594.11 KHN69292.1 - 6e-22 77.3 1.3 6.9e-22 77.1 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Pkinase PF00069.20 KHN69293.1 - 8.5e-71 238.1 0.0 9.6e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69293.1 - 1.1e-40 139.3 0.0 1.4e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69293.1 - 9.4e-05 21.5 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KHN69293.1 - 0.003 16.9 0.0 0.015 14.6 0.0 1.9 1 1 1 2 2 2 1 RIO1 family Pox_ser-thr_kin PF05445.6 KHN69293.1 - 0.038 12.8 0.2 0.11 11.2 0.1 1.9 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 KHN69293.1 - 0.041 13.6 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family GPP34 PF05719.6 KHN69294.1 - 1.6e-22 80.6 0.0 1.9e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) RNase_T PF00929.19 KHN69295.1 - 7.1e-18 65.4 0.0 1.3e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Herpes_UL82_83 PF05784.6 KHN69295.1 - 0.0068 15.2 0.0 0.0098 14.6 0.0 1.2 1 0 0 1 1 1 1 Betaherpesvirus UL82/83 protein N terminus DNA_pol_A_exo1 PF01612.15 KHN69295.1 - 0.044 13.2 0.1 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 3'-5' exonuclease SMC_N PF02463.14 KHN69296.1 - 3e-22 78.9 1.8 9e-22 77.3 1.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KHN69296.1 - 1.6e-06 28.5 66.9 46 4.2 46.3 4.5 1 1 0 1 1 1 0 AAA domain SMC_hinge PF06470.8 KHN69296.1 - 1.3e-05 25.1 0.1 0.00019 21.3 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 KHN69296.1 - 0.00077 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KHN69296.1 - 0.00094 19.2 12.5 0.019 14.9 2.9 3.6 2 2 0 3 3 3 2 AAA domain ABC_tran PF00005.22 KHN69296.1 - 0.82 9.9 0.0 0.82 9.9 0.0 5.0 3 2 0 3 3 3 0 ABC transporter UCH PF00443.24 KHN69298.1 - 4.5e-34 117.7 2.6 7.3e-34 117.0 1.8 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KHN69298.1 - 3e-10 40.0 0.9 8.4e-09 35.2 0.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BRCA-2_OB1 PF09103.5 KHN69301.1 - 3.7e-18 65.3 0.0 6.6e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF221 PF02714.10 KHN69302.1 - 3.9e-66 223.1 20.0 3.9e-66 223.1 13.9 2.2 3 1 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KHN69302.1 - 4.4e-23 81.5 7.1 4.4e-23 81.5 4.9 3.2 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KHN69302.1 - 0.045 14.2 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Ribosomal_L7Ae PF01248.21 KHN69304.1 - 1.1e-21 76.1 0.1 1.4e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KHN69304.1 - 0.0088 15.8 0.0 0.0088 15.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PUF PF00806.14 KHN69306.1 - 8.2e-10 37.6 0.1 0.025 14.0 0.0 4.0 4 0 0 4 4 4 3 Pumilio-family RNA binding repeat MCM PF00493.18 KHN69307.1 - 3e-90 302.3 0.0 4.4e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 KHN69307.1 - 9.5e-06 25.3 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KHN69307.1 - 4.1e-05 22.8 0.3 0.016 14.3 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KHN69307.1 - 6.8e-05 22.3 0.2 0.0033 16.9 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 KHN69307.1 - 0.018 15.3 0.3 0.086 13.1 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 KHN69307.1 - 0.023 14.6 0.2 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_3 PF07726.6 KHN69307.1 - 0.029 13.9 0.0 0.087 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GFA PF04828.9 KHN69307.1 - 0.03 14.2 0.8 0.25 11.2 1.0 2.2 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF815 PF05673.8 KHN69307.1 - 0.041 12.7 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HypA PF01155.14 KHN69307.1 - 0.06 13.0 0.5 0.14 11.8 0.3 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KHN69307.1 - 0.1 12.4 0.8 0.22 11.3 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon AAA_22 PF13401.1 KHN69307.1 - 0.13 12.4 0.9 0.53 10.4 0.1 2.4 2 1 0 2 2 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 KHN69307.1 - 0.18 11.6 0.8 0.38 10.6 0.6 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KHN69307.1 - 0.22 11.4 1.6 0.55 10.2 1.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain CD47 PF04549.9 KHN69308.1 - 0.00072 19.5 16.7 0.00087 19.3 11.6 1.1 1 0 0 1 1 1 1 CD47 transmembrane region DUF962 PF06127.6 KHN69308.1 - 0.0076 16.1 2.3 0.025 14.4 1.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ABC2_membrane_3 PF12698.2 KHN69308.1 - 0.038 13.0 14.9 0.047 12.7 10.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2244 PF10003.4 KHN69308.1 - 2.7 7.3 4.6 0.65 9.3 0.3 2.1 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) DUF202 PF02656.10 KHN69308.1 - 7.3 6.8 6.1 0.84 9.8 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Sel1 PF08238.7 KHN69309.1 - 4.5e-24 84.3 7.8 1.6e-06 28.5 0.0 7.0 7 0 0 7 7 7 5 Sel1 repeat Pkinase PF00069.20 KHN69310.1 - 2.4e-59 200.6 0.0 2.8e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69310.1 - 4.2e-32 111.2 0.0 5e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69310.1 - 8.1e-07 28.2 0.0 1.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KHN69310.1 - 0.00043 20.0 0.0 0.052 13.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KHN69310.1 - 0.049 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 KHN69310.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KHN69310.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1229 PF06797.6 KHN69311.1 - 0.27 10.0 2.4 0.51 9.1 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Glucan_synthase PF02364.10 KHN69312.1 - 0.0054 14.6 0.3 0.0064 14.4 0.2 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Mid2 PF04478.7 KHN69312.1 - 0.0095 15.3 0.9 0.011 15.1 0.7 1.1 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF3671 PF12420.3 KHN69312.1 - 0.027 14.4 0.3 0.042 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function ABA_GPCR PF12430.3 KHN69312.1 - 0.067 12.3 1.4 0.081 12.0 1.0 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor Ninjurin PF04923.7 KHN69312.1 - 1.2 8.9 9.5 9 6.0 6.6 2.1 1 1 0 1 1 1 0 Ninjurin MMR_HSR1 PF01926.18 KHN69315.1 - 1.8e-08 34.3 0.4 6.9e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KHN69315.1 - 2.8e-08 33.1 1.0 6.8e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 AIG1 family MFS_1 PF07690.11 KHN69315.1 - 1.1e-06 27.6 0.2 1.5e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF258 PF03193.11 KHN69315.1 - 1.7e-06 27.3 0.7 4.6e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KHN69315.1 - 0.00059 19.3 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KHN69315.1 - 0.0039 16.1 0.0 0.0095 14.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein GTP_EFTU PF00009.22 KHN69315.1 - 0.0044 16.4 0.1 0.013 14.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain 7TMR-DISM_7TM PF07695.6 KHN69315.1 - 0.0051 16.4 3.9 0.0084 15.7 2.7 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling ABC_tran PF00005.22 KHN69315.1 - 0.0073 16.5 3.7 0.016 15.5 0.0 3.1 3 0 0 3 3 3 1 ABC transporter Dynamin_N PF00350.18 KHN69315.1 - 0.0079 16.0 0.1 0.0079 16.0 0.0 4.4 5 2 2 7 7 7 1 Dynamin family RNA_helicase PF00910.17 KHN69315.1 - 0.011 15.9 0.8 0.14 12.3 0.0 3.2 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 KHN69315.1 - 0.029 14.3 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KHN69315.1 - 0.045 13.6 0.1 0.045 13.6 0.1 3.5 3 1 1 4 4 4 0 AAA domain AAA_22 PF13401.1 KHN69315.1 - 0.058 13.5 0.1 0.2 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KHN69315.1 - 0.079 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 KHN69316.1 - 2.3e-60 204.1 0.7 2.6e-60 203.9 0.5 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KHN69316.1 - 4.8e-06 27.4 0.0 7.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KHN69316.1 - 0.00012 22.3 0.0 0.0006 20.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 KHN69316.1 - 0.00027 20.1 1.0 0.0012 18.0 0.2 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KHN69316.1 - 0.00047 20.1 0.0 0.0013 18.7 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KHN69316.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KHN69316.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN69316.1 - 0.0025 17.7 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KHN69316.1 - 0.01 16.0 0.1 0.051 13.7 0.0 2.2 2 1 1 3 3 3 0 RNA helicase AAA_24 PF13479.1 KHN69316.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KHN69316.1 - 0.047 13.3 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_32 PF13654.1 KHN69316.1 - 0.098 11.2 0.1 0.16 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KHN69316.1 - 0.1 11.7 0.0 0.42 9.7 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 KHN69316.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KHN69316.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KHN69316.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 KHN69318.1 - 8.3e-35 119.8 23.7 1.3e-34 119.1 16.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KHN69318.1 - 3.2e-18 66.3 0.0 5.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KHN69318.1 - 5.1e-09 35.6 18.4 8.2e-09 34.9 12.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 KHN69318.1 - 3.9e-07 30.3 0.6 0.0068 16.4 0.3 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KHN69318.1 - 5.3e-06 25.8 0.0 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KHN69318.1 - 0.00049 19.3 0.0 0.00095 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KHN69318.1 - 0.00082 18.8 0.1 0.0017 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KHN69318.1 - 0.0037 17.1 0.3 0.0079 16.1 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KHN69318.1 - 0.0066 16.5 2.1 0.078 13.1 1.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KHN69318.1 - 0.012 15.1 0.1 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KHN69318.1 - 0.012 15.0 0.5 0.024 14.0 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KHN69318.1 - 0.015 15.6 0.4 0.029 14.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KHN69318.1 - 0.019 15.1 1.3 0.2 11.8 0.9 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KHN69318.1 - 0.025 15.4 0.0 0.068 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KHN69318.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KHN69318.1 - 0.056 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KHN69318.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KHN69318.1 - 0.061 12.7 0.4 1.9 7.8 0.1 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.13 KHN69318.1 - 0.067 12.4 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_33 PF13671.1 KHN69318.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 KHN69318.1 - 3.1 6.5 13.6 8.7 5.1 9.4 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein GHL6 PF14871.1 KHN69319.1 - 0.026 14.5 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 PPV_E1_N PF00524.13 KHN69320.1 - 2.8 8.1 8.1 0.71 10.1 2.7 2.0 1 1 1 2 2 2 0 E1 Protein, N terminal domain PCI PF01399.22 KHN69321.1 - 2.2e-13 50.4 1.3 6.3e-13 48.9 0.6 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KHN69321.1 - 0.0004 20.1 0.8 0.025 14.3 0.1 2.4 2 0 0 2 2 2 2 COP9 signalosome, subunit CSN8 Fer2 PF00111.22 KHN69322.1 - 6.4e-09 35.4 0.1 8.7e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain AAA_23 PF13476.1 KHN69323.1 - 4.5e-20 72.8 0.0 4.5e-20 72.8 0.0 5.7 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.14 KHN69323.1 - 1.7e-10 40.5 10.8 6.6e-06 25.5 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KHN69323.1 - 1.4e-08 35.1 4.6 0.00047 20.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KHN69323.1 - 1.1e-06 28.4 0.0 2.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 KHN69323.1 - 3.4e-05 23.0 0.0 3.4e-05 23.0 0.0 5.5 4 2 1 5 5 5 2 AAA ATPase domain ABC_tran PF00005.22 KHN69323.1 - 0.00036 20.8 8.6 0.082 13.1 0.0 4.5 3 2 1 4 4 4 2 ABC transporter AAA_13 PF13166.1 KHN69323.1 - 0.00054 18.5 0.0 0.00054 18.5 0.0 5.6 3 2 2 6 6 6 2 AAA domain AAA_29 PF13555.1 KHN69323.1 - 0.0066 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KHN69323.1 - 0.059 13.1 0.1 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KHN69323.1 - 0.078 12.9 0.1 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Mis12 PF05859.7 KHN69324.1 - 0.029 14.1 7.3 5.2 6.8 3.6 3.0 1 1 1 2 2 2 0 Mis12 protein CDC37_N PF03234.9 KHN69326.1 - 2.9e-08 34.2 11.1 6.7e-08 33.0 7.7 1.8 1 1 0 1 1 1 1 Cdc37 N terminal kinase binding DUF4381 PF14316.1 KHN69326.1 - 0.061 13.4 0.6 6.1 6.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Vpu PF00558.14 KHN69326.1 - 0.67 9.5 5.2 0.85 9.2 2.2 2.2 2 0 0 2 2 2 0 Vpu protein DUF4355 PF14265.1 KHN69326.1 - 1.6 8.6 13.4 0.32 10.9 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) RPAP1_N PF08621.5 KHN69326.1 - 8.4 6.0 11.6 1.6 8.3 0.2 2.9 3 0 0 3 3 3 0 RPAP1-like, N-terminal DUF788 PF05620.6 KHN69327.1 - 2.3e-12 47.0 1.5 2.8e-12 46.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) YqhR PF11085.3 KHN69327.1 - 0.081 12.4 1.9 0.074 12.5 0.3 1.5 1 1 0 1 1 1 0 Conserved membrane protein YqhR Polysacc_synt_C PF14667.1 KHN69327.1 - 0.15 11.8 4.8 0.48 10.2 0.3 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Hum_adeno_E3A PF05393.6 KHN69327.1 - 0.3 10.7 1.4 0.53 9.9 0.0 2.0 2 1 0 2 2 2 0 Human adenovirus early E3A glycoprotein Rad60-SLD PF11976.3 KHN69328.1 - 1.6e-09 37.2 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Paf1 PF03985.8 KHN69329.1 - 0.0014 17.4 2.7 0.0048 15.7 1.9 1.8 1 1 0 1 1 1 1 Paf1 SMC_N PF02463.14 KHN69330.1 - 2.6e-59 200.1 30.5 4.5e-58 196.0 21.2 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KHN69330.1 - 4.6e-19 68.5 0.0 2.6e-18 66.1 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KHN69330.1 - 1.1e-18 68.2 0.0 1.1e-18 68.2 0.0 5.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KHN69330.1 - 2.4e-12 47.4 8.5 3.1e-07 30.6 0.0 3.3 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KHN69330.1 - 4.7e-08 32.4 0.0 8.7e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KHN69330.1 - 0.045 12.8 0.0 0.045 12.8 0.0 5.1 3 1 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.22 KHN69330.1 - 0.28 11.4 0.1 0.28 11.4 0.1 6.0 4 2 0 4 4 4 0 ABC transporter LURAP PF14854.1 KHN69330.1 - 2.8 7.6 11.1 0.063 12.9 0.6 3.4 3 0 0 3 3 3 0 Leucine rich adaptor protein 2OG-FeII_Oxy_3 PF13640.1 KHN69331.1 - 9.7e-13 48.4 0.2 3.6e-12 46.6 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sec62 PF03839.11 KHN69332.1 - 1.9e-26 92.8 1.3 2.2e-26 92.6 0.9 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.16 KHN69332.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FUSC-like PF12805.2 KHN69332.1 - 0.011 14.7 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF2207 PF09972.4 KHN69332.1 - 0.033 12.7 1.0 0.041 12.4 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Corona_M PF01635.13 KHN69332.1 - 0.35 9.7 6.5 0.47 9.3 4.5 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Med27 PF11571.3 KHN69333.1 - 0.021 14.9 0.7 0.051 13.6 0.2 1.8 2 0 0 2 2 2 0 Mediator complex subunit 27 Med18 PF09637.5 KHN69334.1 - 0.046 13.2 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 Med18 protein PUB PF09409.5 KHN69334.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 PUB domain DUF3087 PF11286.3 KHN69335.1 - 1.5 8.0 7.4 7.4 5.7 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) MIP PF00230.15 KHN69336.1 - 3e-25 89.0 12.0 1.4e-24 86.8 8.3 1.8 1 1 0 1 1 1 1 Major intrinsic protein DUF1072 PF06380.6 KHN69336.1 - 1.1 8.9 5.8 1 9.0 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1072) WD40 PF00400.27 KHN69337.1 - 1.1e-38 129.6 15.8 1.4e-08 34.3 0.3 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KHN69337.1 - 1.2e-26 92.3 0.5 4.4e-26 90.5 0.2 2.1 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex CTDII PF01556.13 KHN69338.1 - 1.4e-16 60.1 5.9 8.6e-11 41.5 0.2 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KHN69338.1 - 4.3e-11 42.6 15.6 9.8e-11 41.5 10.5 1.9 1 1 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 KHN69338.1 - 3e-08 33.2 1.2 7e-08 32.0 0.8 1.7 1 1 0 1 1 1 1 DnaJ domain DZR PF12773.2 KHN69338.1 - 0.057 13.2 12.1 0.11 12.3 2.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon NPL4 PF05021.10 KHN69339.1 - 1.6e-53 181.8 0.0 2.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KHN69339.1 - 6.9e-27 93.9 6.8 4.1e-26 91.3 4.7 2.0 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.13 KHN69339.1 - 6.4e-05 21.9 2.7 6.4e-05 21.9 1.8 2.3 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Sec3_C PF09763.4 KHN69340.1 - 2.9e-18 65.3 10.9 2.9e-18 65.3 7.5 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec3 Hydantoinase_B PF02538.9 KHN69340.1 - 0.078 11.1 1.4 0.16 10.1 1.0 1.4 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Fzo_mitofusin PF04799.8 KHN69340.1 - 8.5 5.7 8.2 3.2 7.1 0.1 3.5 2 1 1 4 4 4 0 fzo-like conserved region Pkinase PF00069.20 KHN69341.1 - 1.1e-62 211.6 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69341.1 - 5.8e-36 123.8 0.0 8.1e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69341.1 - 6.5e-05 22.0 0.0 0.0014 17.7 0.0 2.5 1 1 1 3 3 3 1 Kinase-like APH PF01636.18 KHN69341.1 - 0.036 13.7 0.1 0.28 10.8 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DNA_RNApol_7kD PF03604.8 KHN69341.1 - 0.83 9.1 7.9 0.85 9.1 2.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Rep_fac-A_C PF08646.5 KHN69341.1 - 1.8 8.2 9.1 3.6 7.2 6.3 1.5 1 0 0 1 1 1 0 Replication factor-A C terminal domain DZR PF12773.2 KHN69341.1 - 8.2 6.3 12.5 25 4.7 8.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon Gp_dh_C PF02800.15 KHN69342.1 - 3.6e-57 192.2 0.0 4.8e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KHN69342.1 - 1.8e-41 141.6 0.0 3e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KHN69342.1 - 0.00034 19.8 0.1 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_L10 PF00466.15 KHN69344.1 - 3.7e-19 68.5 2.3 6.4e-19 67.7 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DEAD PF00270.24 KHN69345.1 - 3.3e-28 98.3 0.1 2e-27 95.7 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sec63 PF02889.11 KHN69345.1 - 4.7e-19 68.7 2.1 4.9e-19 68.7 0.8 1.5 1 1 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 KHN69345.1 - 3.8e-07 29.8 0.1 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69345.1 - 0.00041 20.2 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 KHN69345.1 - 0.02 13.8 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Cauli_VI PF01693.11 KHN69345.1 - 0.039 13.9 0.0 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Caulimovirus viroplasmin CobA_CobO_BtuR PF02572.10 KHN69345.1 - 0.085 12.4 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RNA_pol_Rpb8 PF03870.10 KHN69346.1 - 7.1e-15 55.4 0.0 1.3e-12 48.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 PLDc_2 PF13091.1 KHN69346.1 - 0.045 13.5 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 PLD-like domain Cullin PF00888.17 KHN69347.1 - 1.9e-32 112.5 19.1 1.4e-25 89.9 0.3 2.6 2 1 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 KHN69347.1 - 0.00019 21.2 0.1 0.00019 21.2 0.1 2.6 4 0 0 4 4 4 1 Cullin protein neddylation domain HTH_9 PF08221.6 KHN69347.1 - 0.019 14.8 0.2 0.087 12.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Pam16 PF03656.8 KHN69348.1 - 6.8e-07 29.1 0.0 7.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 KHN69348.1 - 0.0004 20.0 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Nop52 PF05997.7 KHN69349.1 - 0.0081 15.6 5.9 0.013 14.9 3.7 1.6 1 1 0 1 1 1 1 Nucleolar protein,Nop52 Rep_fac_C PF08542.6 KHN69349.1 - 0.097 12.6 1.0 0.35 10.8 0.2 2.2 2 1 0 2 2 2 0 Replication factor C C-terminal domain Tfb4 PF03850.9 KHN69350.1 - 6.9e-21 74.7 14.0 2.2e-16 59.9 8.0 2.9 1 1 1 2 2 2 2 Transcription factor Tfb4 NIF PF03031.13 KHN69351.1 - 8.1e-27 93.8 2.2 2.1e-26 92.4 0.1 2.3 2 1 1 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.21 KHN69351.1 - 0.00086 19.4 0.0 0.0072 16.4 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Abhydrolase_5 PF12695.2 KHN69352.1 - 3.5e-09 36.5 0.0 5.6e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KHN69352.1 - 1.7e-08 34.6 0.0 2.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KHN69352.1 - 2e-06 27.5 0.0 3.1e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KHN69352.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase ArgK PF03308.11 KHN69352.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein KTI12 PF08433.5 KHN69353.1 - 1.3e-06 27.8 1.6 0.0046 16.2 0.2 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 DUF3800 PF12686.2 KHN69353.1 - 0.00073 19.2 0.4 0.00097 18.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3800) AsnA PF03590.10 KHN69353.1 - 0.048 13.0 0.3 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 Aspartate-ammonia ligase FtsK_SpoIIIE_N PF12538.3 KHN69353.1 - 0.061 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA transporter Ion_trans PF00520.26 KHN69354.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.6 1 1 0 1 1 1 0 Ion transport protein Ribosomal_L24e PF01246.15 KHN69355.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3509 PF12021.3 KHN69355.1 - 0.035 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Rep_fac-A_3 PF08661.6 KHN69356.1 - 0.066 13.1 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Replication factor A protein 3 RNA_pol_Rpb5_C PF01191.14 KHN69357.1 - 1.6e-28 98.0 0.0 2.8e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KHN69357.1 - 4.5e-11 42.9 0.1 8.9e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain HTH_10 PF04967.7 KHN69357.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 HTH DNA binding domain Phage_pRha PF09669.5 KHN69357.1 - 0.12 12.7 0.2 2.1 8.7 0.0 2.5 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) TMF_TATA_bd PF12325.3 KHN69359.1 - 0.019 14.6 1.9 0.023 14.4 1.3 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ENTH PF01417.15 KHN69359.1 - 0.028 14.2 0.4 0.033 14.0 0.3 1.2 1 0 0 1 1 1 0 ENTH domain DUF2075 PF09848.4 KHN69359.1 - 0.031 13.2 0.3 0.034 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ChuX_HutX PF06228.8 KHN69359.1 - 0.04 13.3 0.1 0.043 13.2 0.1 1.0 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX DivIVA PF05103.8 KHN69359.1 - 0.053 13.5 0.3 0.066 13.2 0.2 1.2 1 0 0 1 1 1 0 DivIVA protein ABC1 PF03109.11 KHN69359.1 - 0.069 13.1 0.3 0.082 12.8 0.2 1.0 1 0 0 1 1 1 0 ABC1 family Hormone_1 PF00103.15 KHN69359.1 - 0.074 12.3 1.5 0.077 12.3 1.0 1.1 1 0 0 1 1 1 0 Somatotropin hormone family DUF3347 PF11827.3 KHN69359.1 - 0.079 12.9 0.7 0.082 12.8 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DUF445 PF04286.7 KHN69359.1 - 0.088 12.3 1.2 0.09 12.2 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Vac_Fusion PF02346.11 KHN69359.1 - 0.096 12.1 0.3 1 8.8 0.1 2.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein DUF3384 PF11864.3 KHN69359.1 - 0.1 11.0 1.5 0.11 10.9 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DUF4284 PF14112.1 KHN69359.1 - 0.21 12.0 1.2 0.23 11.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4284) Diphthamide_syn PF01866.12 KHN69360.1 - 3.7e-92 308.8 0.0 4.8e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein T2SK PF03934.8 KHN69362.1 - 0.015 14.4 0.2 0.026 13.6 0.0 1.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K Beta-Casp PF10996.3 KHN69362.1 - 0.022 14.6 0.6 0.28 11.1 0.1 2.6 2 0 0 2 2 2 0 Beta-Casp domain CDtoxinA PF03498.9 KHN69363.1 - 0.00093 18.6 0.2 0.072 12.4 0.0 2.3 1 1 1 2 2 2 2 Cytolethal distending toxin A/C family Ricin_B_lectin PF00652.17 KHN69363.1 - 0.024 14.6 0.1 0.086 12.8 0.1 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KHN69363.1 - 0.12 12.7 0.0 0.48 10.8 0.0 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Ribosomal_L37ae PF01780.14 KHN69364.1 - 1e-30 105.4 8.1 1.1e-30 105.3 5.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.1 KHN69364.1 - 0.0032 17.6 2.1 2.1 8.8 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.2 KHN69364.1 - 0.0048 16.6 2.0 0.0074 16.0 1.4 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.6 KHN69364.1 - 0.019 14.7 2.2 0.033 14.0 1.4 1.6 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-BED PF02892.10 KHN69364.1 - 0.02 14.6 6.4 0.19 11.5 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger ANP PF00212.13 KHN69364.1 - 0.024 14.7 0.6 0.052 13.6 0.4 1.6 1 0 0 1 1 1 0 Atrial natriuretic peptide C1_1 PF00130.17 KHN69364.1 - 0.038 13.7 2.8 0.059 13.1 1.9 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sgf11 PF08209.6 KHN69364.1 - 0.049 12.9 1.3 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) GCC2_GCC3 PF07699.8 KHN69364.1 - 0.063 12.8 0.4 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 GCC2 and GCC3 zf-C2H2_6 PF13912.1 KHN69364.1 - 0.37 10.7 4.5 5.3 7.0 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C1_2 PF03107.11 KHN69364.1 - 0.44 10.6 4.2 5.4 7.2 0.1 2.2 2 0 0 2 2 2 0 C1 domain FYVE PF01363.16 KHN69364.1 - 1.7 8.6 6.0 12 5.8 4.0 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.21 KHN69364.1 - 1.7 9.1 4.5 22 5.6 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Basic PF01586.11 KHN69364.1 - 3.9 8.2 5.3 6.4 7.5 3.6 1.5 1 1 0 1 1 1 0 Myogenic Basic domain SSrecog PF03531.9 KHN69365.1 - 4.6e-21 75.1 0.2 6.9e-17 61.5 0.0 2.4 1 1 1 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KHN69365.1 - 3.5e-18 65.3 0.7 1.3e-15 57.0 0.0 3.0 3 0 0 3 3 3 2 Histone chaperone Rttp106-like CN_hydrolase PF00795.17 KHN69365.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase WD40 PF00400.27 KHN69366.1 - 5.4e-11 41.9 7.8 0.00045 19.9 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Proteasome PF00227.21 KHN69368.1 - 2.2e-23 82.5 0.0 3.1e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN69368.1 - 8.6e-10 37.7 0.2 1.6e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NAD_kinase PF01513.16 KHN69369.1 - 1.8e-22 79.4 0.4 2.2e-22 79.1 0.3 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 KHN69369.1 - 0.053 12.9 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DEAD PF00270.24 KHN69370.1 - 5.5e-22 78.0 0.8 1.2e-21 76.9 0.5 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69370.1 - 2.7e-14 52.7 0.1 6.3e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 KHN69370.1 - 0.011 15.4 0.1 0.29 10.8 0.0 2.2 1 1 0 2 2 2 0 Flavivirus DEAD domain NIF PF03031.13 KHN69370.1 - 0.022 14.4 0.4 0.098 12.3 0.1 2.1 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase ResIII PF04851.10 KHN69370.1 - 0.046 13.5 0.0 0.096 12.5 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DNA_pol3_a_NII PF11490.3 KHN69371.1 - 0.05 13.2 1.5 0.082 12.5 1.0 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Helicase_C PF00271.26 KHN69374.1 - 3.7e-23 81.1 0.0 1.1e-20 73.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KHN69374.1 - 9.4e-21 74.0 0.0 9.8e-20 70.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 KHN69374.1 - 7.7e-12 44.8 0.2 1.6e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 RQC domain MarR_2 PF12802.2 KHN69374.1 - 0.0019 17.8 0.3 0.011 15.4 0.1 2.2 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 KHN69374.1 - 0.13 12.6 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_24 PF13412.1 KHN69374.1 - 0.15 11.4 1.8 0.16 11.3 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding DUF3449 PF11931.3 KHN69375.1 - 2.3e-28 99.0 4.0 2.3e-28 99.0 2.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-H2C2_5 PF13909.1 KHN69375.1 - 2.2 8.6 6.5 5.2 7.5 1.8 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 KHN69375.1 - 3.7 7.7 13.7 4.6 7.4 1.0 3.4 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Dus PF01207.12 KHN69378.1 - 1.7e-42 145.3 0.0 3e-42 144.5 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) hGDE_central PF14702.1 KHN69379.1 - 0.0036 16.5 0.3 0.0042 16.3 0.2 1.1 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme DUF2089 PF09862.4 KHN69379.1 - 0.019 14.7 0.5 0.038 13.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Tubulin PF00091.20 KHN69380.1 - 4.6e-68 229.2 0.0 6.8e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KHN69380.1 - 2.8e-48 163.1 0.2 4.2e-48 162.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KHN69380.1 - 8.2e-05 22.1 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 KHN69380.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain DUF3551 PF12071.3 KHN69381.1 - 0.072 12.6 1.2 1.8 8.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3551) RPN7 PF10602.4 KHN69381.1 - 0.096 12.0 2.0 0.57 9.5 0.1 2.0 2 0 0 2 2 2 0 26S proteasome subunit RPN7 FH2 PF02181.18 KHN69383.1 - 4.7e-46 157.3 1.9 4.7e-46 157.3 1.3 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KHN69383.1 - 5.5e-05 22.6 0.6 0.0002 20.7 0.4 1.9 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Complex1_30kDa PF00329.14 KHN69383.1 - 0.082 13.1 0.1 0.34 11.1 0.0 2.1 2 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF349 PF03993.7 KHN69383.1 - 1.7 8.8 6.2 2.2 8.5 0.7 3.1 4 0 0 4 4 4 0 Domain of Unknown Function (DUF349) Imm16 PF15565.1 KHN69384.1 - 0.019 14.8 0.6 3.7 7.4 0.2 2.1 1 1 0 2 2 2 0 Immunity protein 16 Death PF00531.17 KHN69384.1 - 0.055 13.2 0.1 9.3 6.1 0.0 2.8 2 1 1 3 3 3 0 Death domain DUF2087 PF09860.4 KHN69384.1 - 0.084 12.6 0.2 2.3 8.0 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) EF-hand_8 PF13833.1 KHN69384.1 - 0.16 11.5 1.6 0.22 11.1 0.3 1.9 2 0 0 2 2 2 0 EF-hand domain pair ABC2_membrane_2 PF12679.2 KHN69386.1 - 0.58 8.9 9.3 0.77 8.5 6.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GDA1_CD39 PF01150.12 KHN69387.1 - 1.5e-21 76.4 1.2 2.5e-21 75.7 0.1 1.6 1 1 1 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KHN69387.1 - 4.5e-06 26.0 0.0 6.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family FtsA PF14450.1 KHN69387.1 - 0.00063 19.5 0.8 0.0041 16.9 0.1 2.4 2 1 1 3 3 3 1 Cell division protein FtsA PilM_2 PF11104.3 KHN69387.1 - 0.041 12.7 0.1 0.077 11.8 0.0 1.5 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Hydantoinase_A PF01968.13 KHN69387.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase HTH_34 PF13601.1 KHN69387.1 - 0.087 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain Pkinase PF00069.20 KHN69388.1 - 2.1e-58 197.5 0.0 2.4e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69388.1 - 5.5e-27 94.4 0.0 7.6e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69388.1 - 0.00024 20.1 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF4160 PF13711.1 KHN69388.1 - 0.0059 16.4 0.1 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4160) APH PF01636.18 KHN69388.1 - 0.06 13.0 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KHN69388.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIS PF01380.17 KHN69389.1 - 2.7e-49 166.1 0.3 7.9e-29 99.9 0.1 2.6 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KHN69389.1 - 2.8e-22 78.9 0.4 1.2e-15 57.1 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KHN69389.1 - 2.2e-19 69.7 0.0 5.6e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KHN69389.1 - 8.3e-15 54.6 0.0 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KHN69389.1 - 5.3e-08 31.8 0.0 1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KHN69389.1 - 0.042 13.5 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 SIS domain Thioredoxin_8 PF13905.1 KHN69389.1 - 0.1 12.6 0.2 8.6 6.5 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin-like CBM_21 PF03370.8 KHN69391.1 - 0.0057 16.6 0.2 0.0099 15.8 0.1 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit FAM72 PF14976.1 KHN69392.1 - 6.4e-19 68.2 11.3 7.7e-19 68.0 7.8 1.1 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 KHN69392.1 - 0.18 11.8 17.2 0.045 13.8 8.5 1.9 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF155 PF02582.9 KHN69393.1 - 1.4e-53 181.4 0.2 1.9e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0193 PF05250.6 KHN69393.1 - 0.016 14.8 0.2 0.025 14.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) DUF3753 PF12575.3 KHN69393.1 - 0.063 13.0 1.6 0.13 12.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF912 PF06024.7 KHN69393.1 - 0.27 11.3 3.0 0.6 10.1 2.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) eIF-5_eIF-2B PF01873.12 KHN69394.1 - 1.3e-30 105.6 0.5 6.7e-29 100.0 0.1 2.1 2 0 0 2 2 2 2 Domain found in IF2B/IF5 FtsJ PF01728.14 KHN69395.1 - 4.6e-50 170.1 0.1 1.3e-49 168.6 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KHN69395.1 - 1.8e-20 73.0 15.9 1.8e-20 73.0 11.0 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3381) Spb1_C PF07780.7 KHN69395.1 - 0.064 12.7 38.0 26 4.2 26.3 3.1 1 1 0 1 1 1 0 Spb1 C-terminal domain CbiA PF01656.18 KHN69395.1 - 0.088 12.1 0.5 0.33 10.3 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Methyltransf_18 PF12847.2 KHN69395.1 - 0.1 13.2 0.1 1.2 9.7 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain ATP-synt_C PF00137.16 KHN69396.1 - 6.1e-16 58.0 13.8 1e-09 38.1 3.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C RRM_6 PF14259.1 KHN69398.1 - 2e-05 24.5 0.6 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN69398.1 - 7.4e-05 22.3 1.5 0.0078 15.8 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69398.1 - 0.0019 17.9 0.3 0.0049 16.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AsnC_trans_reg PF01037.16 KHN69398.1 - 0.0024 17.5 1.0 0.031 13.9 0.2 2.4 2 0 0 2 2 2 1 AsnC family ubiquitin PF00240.18 KHN69399.1 - 8.4e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 KHN69399.1 - 9.7e-05 21.8 11.8 0.00017 21.0 8.2 1.4 1 0 0 1 1 1 1 Ribosomal L40e family TUG-UBL1 PF11470.3 KHN69399.1 - 0.0086 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Rad60-SLD PF11976.3 KHN69399.1 - 0.042 13.5 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L22 PF00237.14 KHN69400.1 - 3.2e-36 123.4 0.3 3.8e-36 123.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Proteasome PF00227.21 KHN69401.1 - 1.5e-26 92.8 0.0 2.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF4163 PF13739.1 KHN69402.1 - 0.8 10.5 15.6 0.2 12.4 0.3 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4163) Dopey_N PF04118.9 KHN69403.1 - 9.2e-72 241.4 1.7 9.2e-72 241.4 1.2 3.4 3 1 0 3 3 3 2 Dopey, N-terminal Ribosomal_L37e PF01907.14 KHN69405.1 - 1.1e-19 69.9 8.6 1.1e-19 69.9 5.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 KHN69405.1 - 0.0013 18.4 3.4 0.002 17.8 2.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon RNA_POL_M_15KD PF02150.11 KHN69405.1 - 3.7 7.3 8.1 34 4.2 0.7 2.2 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit DUF869 PF05911.6 KHN69408.1 - 0.0026 16.1 4.6 0.0027 16.0 3.2 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Dynactin PF12455.3 KHN69408.1 - 0.0036 16.2 2.4 0.0053 15.7 1.6 1.6 1 1 0 1 1 1 1 Dynein associated protein MAP65_ASE1 PF03999.7 KHN69408.1 - 0.0046 15.6 5.0 0.017 13.7 2.4 1.9 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) GAS PF13851.1 KHN69408.1 - 0.0067 15.6 6.1 0.0083 15.3 4.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TACC PF05010.9 KHN69408.1 - 0.0067 16.2 5.8 0.0085 15.8 4.0 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) ATG16 PF08614.6 KHN69408.1 - 0.0087 15.8 6.0 0.012 15.4 4.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc7 PF08317.6 KHN69408.1 - 0.013 14.1 4.9 0.016 13.9 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein RE_ScaI PF09569.5 KHN69408.1 - 0.018 14.5 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 ScaI restriction endonuclease CENP-F_leu_zip PF10473.4 KHN69408.1 - 0.026 14.3 7.2 0.041 13.7 5.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 KHN69408.1 - 0.045 13.2 4.4 0.067 12.6 3.0 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Prominin PF05478.6 KHN69408.1 - 0.081 10.4 5.0 0.091 10.2 3.1 1.3 1 1 0 1 1 1 0 Prominin ADIP PF11559.3 KHN69408.1 - 0.093 12.6 12.0 0.1 12.4 7.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 KHN69408.1 - 0.11 10.7 7.3 0.068 11.4 3.8 1.3 1 1 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.3 KHN69408.1 - 0.11 11.7 4.0 0.17 11.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 KHN69408.1 - 0.14 11.1 6.2 0.17 10.9 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 KHN69408.1 - 0.18 11.6 8.4 0.31 10.8 4.7 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Sec20 PF03908.8 KHN69408.1 - 0.22 11.2 3.7 0.68 9.6 0.4 2.2 2 0 0 2 2 2 0 Sec20 DUF904 PF06005.7 KHN69408.1 - 0.34 11.2 10.9 0.79 10.0 7.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 KHN69408.1 - 0.37 10.5 4.2 0.24 11.1 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2543 PF10820.3 KHN69408.1 - 0.38 10.8 3.0 0.9 9.5 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2543) AKNA PF12443.3 KHN69408.1 - 0.55 10.2 6.0 7.9 6.5 4.1 2.3 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF972 PF06156.8 KHN69408.1 - 0.59 10.5 9.1 0.71 10.2 5.1 2.0 2 1 1 3 3 2 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 KHN69408.1 - 0.72 9.8 12.3 0.5 10.3 5.2 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Latarcin PF10279.4 KHN69408.1 - 0.85 9.8 8.5 0.6 10.3 3.0 2.1 1 1 1 2 2 2 0 Latarcin precursor V_ATPase_I PF01496.14 KHN69408.1 - 1.5 6.5 5.2 1.8 6.3 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KHN69408.1 - 1.6 7.0 8.1 1.9 6.8 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF2630 PF10944.3 KHN69408.1 - 5.4 7.1 8.1 11 6.2 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) bZIP_2 PF07716.10 KHN69408.1 - 6 6.7 11.8 9.6 6.1 0.4 2.8 2 1 0 2 2 2 0 Basic region leucine zipper E1-E2_ATPase PF00122.15 KHN69409.1 - 3.4e-22 78.6 0.2 3.4e-22 78.6 0.1 3.8 3 1 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KHN69409.1 - 4.1e-20 72.7 0.0 1.3e-19 71.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KHN69409.1 - 6.1e-18 66.0 0.0 1.6e-13 51.5 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KHN69409.1 - 6.8e-12 45.2 0.1 1.8e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 KHN69409.1 - 1.6e-05 24.7 0.1 4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KHN69409.1 - 0.014 15.0 0.2 0.09 12.3 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Y_phosphatase PF00102.22 KHN69409.1 - 0.09 12.0 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Phage_Gp23 PF10669.4 KHN69410.1 - 0.68 10.0 4.5 0.98 9.5 0.2 2.5 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RelB PF04221.7 KHN69413.1 - 0.07 12.8 0.4 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 RelB antitoxin tRNA-synt_2b PF00587.20 KHN69414.1 - 5.2e-39 133.5 1.4 1.2e-38 132.3 0.4 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.9 KHN69414.1 - 6.7e-11 41.9 0.0 2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HGTP_anticodon PF03129.15 KHN69414.1 - 1.3e-09 37.8 0.4 1.3e-09 37.8 0.3 2.1 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 KHN69414.1 - 0.22 11.3 1.2 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 TGS domain Lectin_leg-like PF03388.8 KHN69417.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Legume-like lectin family Spc7 PF08317.6 KHN69417.1 - 0.029 13.0 1.6 0.044 12.4 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Taxilin PF09728.4 KHN69417.1 - 0.05 12.6 1.5 0.074 12.1 1.0 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Dus PF01207.12 KHN69418.1 - 2.1e-68 230.4 0.1 2.9e-68 230.0 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KHN69418.1 - 0.0007 18.9 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein DHO_dh PF01180.16 KHN69418.1 - 0.0019 17.1 0.0 0.089 11.7 0.0 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase ThiG PF05690.9 KHN69418.1 - 0.033 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 KHN69418.1 - 0.088 11.6 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase V-SNARE_C PF12352.3 KHN69419.1 - 0.00011 22.1 1.5 0.0003 20.7 0.8 1.9 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KHN69419.1 - 0.027 14.1 1.0 0.063 12.9 0.1 2.1 2 2 0 2 2 2 0 Sec20 DCP2 PF05026.8 KHN69420.1 - 1.6e-15 56.7 0.5 4.5e-15 55.2 0.3 1.8 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KHN69420.1 - 6.7e-12 45.1 0.0 1.8e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Tbf5 PF06331.7 KHN69420.1 - 0.14 11.9 0.4 0.91 9.3 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 AAA PF00004.24 KHN69421.1 - 2.1e-40 137.9 0.0 4.9e-40 136.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KHN69421.1 - 1.2e-06 28.6 0.2 0.00032 20.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KHN69421.1 - 1.8e-05 24.7 0.0 5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KHN69421.1 - 3.4e-05 22.8 0.0 6.1e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KHN69421.1 - 0.00019 21.1 1.0 0.00091 18.9 0.2 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KHN69421.1 - 0.00093 19.2 0.0 0.0037 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KHN69421.1 - 0.0018 17.3 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KHN69421.1 - 0.0023 18.7 0.1 0.0062 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN69421.1 - 0.0034 17.2 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KHN69421.1 - 0.005 16.7 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KHN69421.1 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KHN69421.1 - 0.0088 14.9 0.0 0.094 11.5 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain IstB_IS21 PF01695.12 KHN69421.1 - 0.0089 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KHN69421.1 - 0.011 15.1 0.4 0.25 10.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 KHN69421.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KHN69421.1 - 0.02 14.6 0.1 0.039 13.6 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 KHN69421.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 KHN69421.1 - 0.036 14.3 0.2 0.074 13.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KHN69421.1 - 0.046 13.3 0.4 0.47 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain UPF0086 PF01868.11 KHN69422.1 - 6.2e-05 22.5 0.7 0.00021 20.8 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Mob_Pre PF01076.14 KHN69423.1 - 0.016 14.8 1.0 0.019 14.6 0.7 1.0 1 0 0 1 1 1 0 Plasmid recombination enzyme bZIP_1 PF00170.16 KHN69423.1 - 1.8 8.5 6.4 0.68 9.9 1.7 2.3 3 1 0 3 3 3 0 bZIP transcription factor tRNA-synt_2d PF01409.15 KHN69424.1 - 2.1e-91 305.5 0.0 2.8e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KHN69424.1 - 1.8e-05 23.7 0.1 0.0029 16.4 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KHN69424.1 - 7e-05 22.4 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Acetyltransf_1 PF00583.19 KHN69426.1 - 2.9e-06 27.2 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KHN69426.1 - 0.00025 20.7 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KHN69426.1 - 0.0014 18.6 0.1 0.0016 18.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KHN69426.1 - 0.002 18.2 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SH2_2 PF14633.1 KHN69427.1 - 1.3e-10 40.7 1.6 3.4e-10 39.3 1.1 1.7 1 1 0 1 1 1 1 SH2 domain TIP_N PF12457.3 KHN69427.1 - 0.15 12.1 0.5 0.34 10.9 0.3 1.7 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Ribosomal_S5 PF00333.15 KHN69428.1 - 2.3e-20 72.1 2.8 4.2e-20 71.2 1.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KHN69428.1 - 7.3e-19 66.8 0.1 1.4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Cystatin PF00031.16 KHN69428.1 - 0.11 12.6 0.3 0.34 11.0 0.1 1.8 2 0 0 2 2 2 0 Cystatin domain VPS9 PF02204.13 KHN69429.1 - 2.2e-19 69.3 0.3 5.5e-19 68.1 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RRM_1 PF00076.17 KHN69430.1 - 5.9e-15 54.6 0.1 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69430.1 - 3.5e-10 39.7 0.0 0.00068 19.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69430.1 - 1.2e-08 34.6 0.7 0.00035 20.3 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRF-TF PF00319.13 KHN69432.1 - 2.2e-18 65.2 0.2 4.1e-18 64.3 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SHS2_Rpb7-N PF03876.12 KHN69433.1 - 2.8e-10 40.1 0.0 5.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KHN69433.1 - 1.5e-07 31.3 0.1 3e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain GPDPase_memb PF10110.4 KHN69433.1 - 0.13 11.6 0.2 0.33 10.3 0.1 1.7 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF3671 PF12420.3 KHN69434.1 - 0.066 13.2 1.3 0.1 12.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function ABA_GPCR PF12430.3 KHN69434.1 - 0.07 12.2 2.1 0.086 11.9 1.4 1.1 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor Ninjurin PF04923.7 KHN69434.1 - 0.58 9.9 9.1 0.51 10.0 3.6 2.1 1 1 1 2 2 2 0 Ninjurin Glycoprotein_G PF00802.14 KHN69434.1 - 0.92 8.5 3.0 1.1 8.3 2.1 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF4519 PF15012.1 KHN69435.1 - 0.046 13.6 0.8 0.046 13.6 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Latarcin PF10279.4 KHN69435.1 - 0.15 12.2 7.5 0.31 11.2 0.3 3.0 2 2 0 2 2 2 0 Latarcin precursor Rubredoxin PF00301.15 KHN69436.1 - 0.062 13.1 0.6 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Rubredoxin YlaH PF14036.1 KHN69436.1 - 0.078 13.0 0.1 0.078 13.0 0.1 2.4 3 0 0 3 3 3 0 YlaH-like protein Anoctamin PF04547.7 KHN69438.1 - 0.013 14.1 11.6 0.016 13.9 8.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2911 PF11138.3 KHN69438.1 - 0.28 10.8 4.7 0.48 10.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Myb_DNA-binding PF00249.26 KHN69439.1 - 7.1e-21 74.0 5.5 2.3e-09 37.1 0.1 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KHN69439.1 - 3.2e-17 62.3 12.2 7.1e-11 42.0 0.0 4.7 3 2 2 5 5 5 3 Myb-like DNA-binding domain Rap1_C PF11626.3 KHN69439.1 - 0.0014 18.4 0.1 0.0045 16.8 0.0 2.0 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain RHD3 PF05879.7 KHN69439.1 - 0.0064 14.4 1.8 0.0097 13.8 1.3 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Myb_DNA-bind_4 PF13837.1 KHN69439.1 - 0.031 14.3 15.4 0.079 13.0 0.7 4.9 2 2 2 5 5 5 0 Myb/SANT-like DNA-binding domain MtrD PF04207.7 KHN69439.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D MADF_DNA_bdg PF10545.4 KHN69439.1 - 0.1 12.7 0.2 0.1 12.7 0.2 3.5 2 2 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like RTC PF01137.16 KHN69440.1 - 1.5e-34 118.7 0.0 2.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KHN69440.1 - 2.3e-08 33.9 0.0 4.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1414 PF07208.6 KHN69440.1 - 0.89 9.3 3.3 0.7 9.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1414) Ribul_P_3_epim PF00834.14 KHN69441.1 - 4.9e-45 153.1 1.1 5.7e-45 152.9 0.8 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family zf-CCCH PF00642.19 KHN69442.1 - 7.3e-08 31.9 2.1 1.9e-07 30.5 1.4 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.20 KHN69442.1 - 5.5e-06 25.9 11.2 1.2e-05 24.8 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN69442.1 - 8.5e-06 25.3 10.5 8.5e-06 25.3 7.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KHN69442.1 - 2.4e-05 24.2 12.7 2.4e-05 24.2 8.8 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69442.1 - 4.6e-05 23.0 11.3 9.6e-05 22.0 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KHN69442.1 - 0.0002 21.1 11.7 0.00058 19.6 8.2 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KHN69442.1 - 0.0016 18.1 2.9 0.0031 17.1 2.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KHN69442.1 - 0.0018 18.0 8.0 0.0043 16.8 5.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KHN69442.1 - 0.016 15.3 10.7 0.051 13.6 6.8 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger DUF1137 PF06587.6 KHN69442.1 - 0.12 12.0 2.0 0.14 11.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) BmKX PF09132.5 KHN69442.1 - 0.66 9.8 0.1 0.66 9.8 0.1 3.1 4 1 0 4 4 3 0 BmKX Zn_Tnp_IS91 PF14319.1 KHN69442.1 - 2.1 7.8 8.4 0.53 9.8 3.7 1.6 1 1 0 1 1 1 0 Transposase zinc-binding domain zf-Apc11 PF12861.2 KHN69442.1 - 2.2 8.1 10.5 51 3.7 6.0 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KHN69442.1 - 3.3 7.3 9.1 18 4.9 6.3 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L19e PF01280.15 KHN69443.1 - 2.2e-51 173.5 11.2 2.7e-51 173.2 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e SHOCT PF09851.4 KHN69443.1 - 0.00031 20.1 0.0 0.00084 18.7 0.0 1.8 1 0 0 1 1 1 1 Short C-terminal domain Siah-Interact_N PF09032.6 KHN69443.1 - 0.02 14.9 0.2 0.043 13.8 0.1 1.6 1 0 0 1 1 1 0 Siah interacting protein, N terminal Evr1_Alr PF04777.8 KHN69444.1 - 5.6e-29 99.8 0.4 9.2e-29 99.1 0.3 1.3 1 0 0 1 1 1 1 Erv1 / Alr family TFIIB PF00382.14 KHN69445.1 - 1.6e-39 133.5 4.1 2.1e-22 78.7 0.4 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KHN69445.1 - 5.6e-13 47.9 3.3 5.6e-13 47.9 2.3 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 KHN69445.1 - 0.0001 21.8 0.3 0.0011 18.5 0.0 2.3 1 1 1 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.15 KHN69445.1 - 0.053 13.0 0.7 0.13 11.7 0.2 1.8 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain Cyclin_C PF02984.14 KHN69445.1 - 0.12 12.2 0.3 2 8.3 0.0 2.2 1 1 1 2 2 2 0 Cyclin, C-terminal domain Ribosomal_S13 PF00416.17 KHN69446.1 - 3.8e-27 94.8 0.9 4.4e-27 94.6 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KHN69446.1 - 0.0014 17.2 0.0 0.0018 16.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L36e PF01158.13 KHN69447.1 - 6.7e-10 38.8 4.7 7.3e-10 38.6 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e COG2 PF06148.6 KHN69447.1 - 0.097 12.5 0.2 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FTCD_N PF07837.7 KHN69448.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain OmpH PF03938.9 KHN69449.1 - 1.8 8.4 8.4 1.8 8.5 5.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LSM PF01423.17 KHN69450.1 - 7.1e-06 25.4 0.0 8.1e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KHN69450.1 - 0.00079 19.2 0.0 0.00085 19.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Vps26 PF03643.10 KHN69450.1 - 0.038 12.7 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Gemin6 PF06372.7 KHN69450.1 - 0.098 11.9 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 Gemin6 protein zf-H2C2_2 PF13465.1 KHN69451.1 - 3.1e-07 30.3 0.3 3.1e-07 30.3 0.2 3.1 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KHN69451.1 - 2.9e-05 24.1 1.2 2.9e-05 24.1 0.8 3.5 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KHN69451.1 - 0.0011 19.1 0.5 0.0011 19.1 0.3 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-BED PF02892.10 KHN69451.1 - 0.023 14.4 1.1 0.023 14.4 0.7 1.9 2 0 0 2 2 2 0 BED zinc finger Vps54 PF07928.7 KHN69451.1 - 0.1 12.6 0.6 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 Vps54-like protein T_hemolysin PF12261.3 KHN69452.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Thermostable hemolysin Lebercilin PF15619.1 KHN69452.1 - 0.05 13.0 10.0 0.084 12.2 2.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PaaSYMP PF14738.1 KHN69453.1 - 0.021 14.5 2.7 0.038 13.7 1.9 1.4 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 YchF-GTPase_C PF06071.8 KHN69454.1 - 8.1e-35 118.4 0.3 2e-34 117.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KHN69454.1 - 4.1e-18 65.4 0.0 9.5e-18 64.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KHN69454.1 - 6.1e-09 35.3 0.1 8.3e-08 31.6 0.0 2.5 2 1 1 3 3 3 1 Ferrous iron transport protein B AAA_17 PF13207.1 KHN69454.1 - 0.0061 17.3 0.7 0.16 12.8 0.0 2.6 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 KHN69454.1 - 0.0095 16.2 0.1 0.03 14.6 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 KHN69454.1 - 0.011 15.5 0.3 0.094 12.6 0.0 2.7 2 2 0 3 3 3 0 AAA domain DUF3954 PF13128.1 KHN69454.1 - 0.015 14.7 0.1 0.046 13.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) ArgK PF03308.11 KHN69454.1 - 0.051 12.3 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 ArgK protein Dynamin_N PF00350.18 KHN69454.1 - 0.11 12.3 1.4 5.4 6.8 0.9 3.1 1 1 0 1 1 1 0 Dynamin family SAP PF02037.22 KHN69455.1 - 1.1e-09 37.5 0.0 2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain CSS-motif PF12792.2 KHN69455.1 - 0.037 13.3 0.1 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 CSS motif domain associated with EAL DUF1319 PF07028.6 KHN69456.1 - 0.066 13.4 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Ribosomal_L14e PF01929.12 KHN69457.1 - 0.0061 16.8 0.2 0.023 15.0 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L14 Med21 PF11221.3 KHN69458.1 - 0.09 12.7 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex TPR_2 PF07719.12 KHN69459.1 - 1.1e-12 46.7 6.5 0.71 9.9 0.0 8.7 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 KHN69459.1 - 3.7e-05 23.2 12.4 0.38 10.6 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KHN69459.1 - 6.6e-05 22.9 1.2 0.11 12.6 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KHN69459.1 - 8.4e-05 22.0 10.5 6.1 6.6 0.0 7.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KHN69459.1 - 9.3e-05 22.9 0.0 2.6 8.8 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KHN69459.1 - 0.00043 20.5 5.8 0.99 9.7 0.0 5.6 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69459.1 - 0.00069 19.5 3.6 8 6.4 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 KHN69459.1 - 0.00085 18.9 15.6 7.1 6.3 0.0 8.5 9 2 1 10 10 10 1 TPR repeat TPR_6 PF13174.1 KHN69459.1 - 0.012 16.0 0.4 31 5.3 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat Toprim_Crpt PF13342.1 KHN69459.1 - 0.022 14.3 0.5 0.11 12.0 0.3 2.3 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase DUF2007 PF09413.5 KHN69459.1 - 0.034 13.9 2.1 11 5.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF2007) TPR_10 PF13374.1 KHN69459.1 - 0.044 13.7 0.3 2.7 8.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TruD PF01142.13 KHN69460.1 - 6.6e-40 136.9 0.2 9e-27 93.7 0.0 4.0 3 1 1 4 4 4 3 tRNA pseudouridine synthase D (TruD) XPG_I_2 PF12813.2 KHN69460.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing C1_3 PF07649.7 KHN69461.1 - 0.0023 17.9 0.2 0.0053 16.7 0.1 1.6 1 0 0 1 1 1 1 C1-like domain DEAD PF00270.24 KHN69462.1 - 4.8e-24 84.7 2.2 7.8e-18 64.5 0.1 2.6 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69462.1 - 4.7e-15 55.2 0.1 1.4e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69462.1 - 2e-08 34.2 0.4 3.2e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 KHN69462.1 - 0.002 17.4 0.2 0.0056 15.9 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein SecA_DEAD PF07517.9 KHN69462.1 - 0.0025 17.1 0.5 0.037 13.3 0.0 2.3 1 1 1 2 2 2 1 SecA DEAD-like domain Flavi_DEAD PF07652.9 KHN69462.1 - 0.01 15.5 0.7 0.028 14.1 0.1 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_19 PF13245.1 KHN69462.1 - 0.086 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KHN69462.1 - 1.1 9.4 3.8 31 4.7 2.7 2.5 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.14 KHN69463.1 - 5.3e-05 23.4 1.0 0.25 11.6 0.2 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box Jiv90 PF14901.1 KHN69463.1 - 0.0046 16.9 5.1 0.0067 16.3 1.6 2.5 2 1 0 2 2 2 1 Cleavage inducing molecular chaperone HMG_box_2 PF09011.5 KHN69463.1 - 0.018 15.3 6.2 0.019 15.3 0.6 2.6 2 0 0 2 2 2 0 HMG-box domain AdoMet_dc PF02675.10 KHN69463.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase DUF1289 PF06945.8 KHN69463.1 - 0.057 12.8 0.9 0.16 11.4 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1289) HMG_box PF00505.14 KHN69464.1 - 8.7e-24 83.5 11.6 8.6e-13 48.3 2.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KHN69464.1 - 3.9e-17 62.3 13.0 1e-09 38.6 1.4 2.6 2 1 0 2 2 2 2 HMG-box domain YABBY PF04690.8 KHN69464.1 - 0.00027 21.2 2.9 0.00037 20.7 2.0 1.4 1 1 0 1 1 1 1 YABBY protein CHDNT PF08073.7 KHN69464.1 - 0.00056 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF1074 PF06382.6 KHN69464.1 - 0.0017 18.3 1.9 0.0017 18.3 1.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1074) KRAB PF01352.22 KHN69464.1 - 0.016 14.6 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 KRAB box Dus PF01207.12 KHN69464.1 - 0.66 8.7 3.9 0.69 8.6 1.7 1.5 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) SNAP PF14938.1 KHN69465.1 - 9.2e-11 41.4 7.7 2e-10 40.2 4.5 1.9 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KHN69465.1 - 1.8e-05 24.6 1.0 0.0029 17.5 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KHN69465.1 - 0.11 12.2 15.4 0.89 9.4 0.1 5.1 5 2 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 KHN69465.1 - 0.55 10.4 5.6 0.44 10.7 1.2 2.6 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.15 KHN69465.1 - 1.1 10.1 6.4 2e+02 3.3 0.0 5.5 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat TPT PF03151.11 KHN69466.1 - 6.5e-15 55.0 13.1 6.5e-15 55.0 9.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KHN69466.1 - 0.00046 20.2 8.5 0.00046 20.2 5.9 2.9 2 2 1 3 3 3 2 EamA-like transporter family MtN3_slv PF03083.11 KHN69466.1 - 0.016 15.0 2.2 0.016 15.0 1.5 2.8 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF1129 PF06570.6 KHN69466.1 - 1.3 8.2 8.1 0.69 9.1 3.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) ATP_bind_1 PF03029.12 KHN69467.1 - 5.7e-31 107.8 0.0 6.6e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KHN69467.1 - 2.5e-05 23.8 0.0 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 KHN69467.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 KHN69467.1 - 0.0035 16.4 0.0 0.02 14.0 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KHN69467.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KHN69467.1 - 0.019 15.7 0.5 0.042 14.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KHN69467.1 - 0.037 14.0 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 KHN69467.1 - 0.045 12.5 0.0 5.1 5.7 0.0 2.4 3 0 0 3 3 3 0 ArgK protein AAA_29 PF13555.1 KHN69467.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KHN69467.1 - 0.057 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KHN69467.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KHN69467.1 - 0.081 12.8 0.0 0.36 10.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KHN69467.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KHN69467.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RINGv PF12906.2 KHN69468.1 - 8.8e-11 41.6 6.1 1.3e-10 41.0 4.2 1.3 1 0 0 1 1 1 1 RING-variant domain DUF996 PF06195.8 KHN69468.1 - 0.72 9.8 8.5 0.84 9.6 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF996) PhrC_PhrF PF11131.3 KHN69469.1 - 0.07 12.7 0.1 0.71 9.4 0.0 2.4 2 0 0 2 2 2 0 Rap-phr extracellular signalling Diphthamide_syn PF01866.12 KHN69470.1 - 4e-12 45.9 0.0 7.5e-12 45.1 0.0 1.4 2 0 0 2 2 2 1 Putative diphthamide synthesis protein SIS_2 PF13580.1 KHN69470.1 - 0.051 13.2 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 SIS domain DnaJ PF00226.26 KHN69472.1 - 2.8e-07 30.1 0.9 1.2e-06 28.0 0.1 2.4 2 1 0 2 2 2 1 DnaJ domain EntA_Immun PF08951.5 KHN69472.1 - 0.036 14.1 0.7 0.083 13.0 0.2 1.8 1 1 0 1 1 1 0 Enterocin A Immunity DUF1292 PF06949.6 KHN69473.1 - 0.011 16.0 0.0 0.042 14.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) DUF4539 PF15072.1 KHN69474.1 - 3.9e-06 26.4 0.1 7.8e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4539) tRNA_anti-codon PF01336.20 KHN69474.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain IFN-gamma PF00714.12 KHN69474.1 - 0.061 13.1 0.5 0.095 12.5 0.3 1.3 1 0 0 1 1 1 0 Interferon gamma DUF1284 PF06935.6 KHN69474.1 - 0.17 12.0 2.5 0.21 11.7 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1284) Ferritin PF00210.19 KHN69475.1 - 3.4e-27 94.9 0.2 4.2e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 KHN69475.1 - 0.0003 21.1 0.2 0.00042 20.6 0.1 1.2 1 0 0 1 1 1 1 Rubrerythrin DUF2383 PF09537.5 KHN69475.1 - 0.056 13.6 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Phenol_Hydrox PF02332.13 KHN69475.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase FbpA PF05833.6 KHN69476.1 - 3.3e-33 114.9 4.7 4.4e-33 114.5 3.2 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KHN69476.1 - 4.7e-22 77.6 0.0 1.8e-21 75.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 KHN69476.1 - 1.7e-20 72.6 0.2 6.5e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) DUF2203 PF09969.4 KHN69476.1 - 0.0034 17.5 3.5 2.2 8.5 0.0 3.5 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2203) CDT1 PF08839.6 KHN69477.1 - 6e-07 29.5 1.6 2.8e-05 24.0 0.1 2.7 3 0 0 3 3 3 2 DNA replication factor CDT1 like Sld5 PF05916.6 KHN69478.1 - 3.1e-14 53.1 0.5 4.8e-14 52.5 0.3 1.4 1 0 0 1 1 1 1 GINS complex protein VTC PF09359.5 KHN69479.1 - 9e-85 284.1 0.6 9e-85 284.1 0.4 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.10 KHN69479.1 - 3.8e-12 46.2 2.5 7.2e-12 45.3 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.14 KHN69479.1 - 4.5e-08 33.2 18.2 0.00019 21.3 1.1 3.2 1 1 2 3 3 3 3 SPX domain TPR_1 PF00515.23 KHN69480.1 - 2.4e-27 93.3 8.9 0.00019 20.8 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 KHN69480.1 - 3.7e-25 87.3 13.1 1e-09 37.8 0.7 4.7 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 KHN69480.1 - 4.3e-24 82.4 4.5 0.002 17.9 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 KHN69480.1 - 3.9e-23 79.4 13.8 3.1e-05 23.4 1.4 6.8 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 KHN69480.1 - 3.4e-15 54.8 7.1 6.7e-05 22.7 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69480.1 - 4.2e-14 52.2 11.0 7e-06 25.8 0.2 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 KHN69480.1 - 6.5e-11 42.2 16.6 4.1e-06 26.8 1.0 5.1 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KHN69480.1 - 8.6e-10 38.3 0.0 0.74 10.6 0.0 6.4 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KHN69480.1 - 5.6e-09 35.1 4.2 0.012 15.3 0.0 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KHN69480.1 - 2.3e-08 34.4 0.2 0.00062 20.3 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KHN69480.1 - 3e-08 33.5 6.7 0.074 13.5 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KHN69480.1 - 5.2e-07 29.9 0.1 0.0045 17.2 0.0 4.3 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.1 KHN69480.1 - 3e-05 23.2 0.1 0.00056 19.0 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 KHN69480.1 - 0.00048 18.9 0.3 0.19 10.4 0.1 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 KHN69480.1 - 0.00081 19.2 0.0 0.14 12.0 0.0 2.9 2 1 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.15 KHN69480.1 - 0.024 14.6 7.5 0.85 9.7 0.0 5.2 7 0 0 7 7 5 0 PPR repeat GTP_EFTU PF00009.22 KHN69481.1 - 3.6e-41 140.6 0.0 5e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KHN69481.1 - 2.1e-13 50.2 0.1 4.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 KHN69481.1 - 6.9e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KHN69481.1 - 0.00095 18.3 0.0 0.0062 15.7 0.0 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KHN69481.1 - 0.0017 18.8 0.0 0.0078 16.6 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KHN69481.1 - 0.041 13.0 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S26e PF01283.14 KHN69482.1 - 4.1e-38 130.1 4.0 4.3e-38 130.0 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Auxin_resp PF06507.8 KHN69482.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Auxin response factor CDC50 PF03381.10 KHN69483.1 - 2.8e-38 131.6 0.3 4.9e-38 130.8 0.1 1.3 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sec1 PF00995.18 KHN69484.1 - 9.5e-54 182.9 5.2 1.1e-49 169.5 3.5 2.0 2 0 0 2 2 2 2 Sec1 family Dehydratase_hem PF13816.1 KHN69484.1 - 0.14 11.1 0.1 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase KH_1 PF00013.24 KHN69485.1 - 7.3e-17 60.7 17.7 9.8e-10 37.9 0.4 3.7 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KHN69485.1 - 1.5e-11 43.6 17.6 1.4e-08 34.1 0.9 3.9 3 0 0 3 3 3 3 KH domain HATPase_c_5 PF14501.1 KHN69485.1 - 0.0057 16.3 2.7 0.0075 15.9 0.5 2.2 2 0 0 2 2 2 1 GHKL domain AA_permease_2 PF13520.1 KHN69486.1 - 2.2e-29 102.2 41.1 6.7e-29 100.6 28.5 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KHN69486.1 - 1.6e-21 76.1 38.4 4.8e-21 74.6 26.6 1.8 1 1 0 1 1 1 1 Amino acid permease HEAT_2 PF13646.1 KHN69487.1 - 3.1e-22 78.6 0.0 1.8e-09 37.7 0.0 3.3 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 KHN69487.1 - 2.8e-15 55.1 0.0 0.0012 19.0 0.0 5.4 5 0 0 5 5 5 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KHN69487.1 - 0.00046 20.5 0.0 1.2 9.6 0.0 3.4 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 KHN69487.1 - 0.0012 18.6 0.0 2.5 8.4 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HlyIII PF03006.15 KHN69488.1 - 1e-29 103.5 16.8 1.3e-29 103.2 11.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related Plug_translocon PF10559.4 KHN69488.1 - 1.6 8.2 6.9 0.12 11.9 0.6 2.1 2 0 0 2 2 2 0 Plug domain of Sec61p NOT2_3_5 PF04153.13 KHN69489.1 - 2.2e-35 121.4 8.0 4.2e-35 120.5 5.6 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family NTP_transf_2 PF01909.18 KHN69490.1 - 2.3e-08 34.2 0.0 5.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 KHN69490.1 - 0.015 15.2 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain DNA_pol_B_palm PF14792.1 KHN69490.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm PAP_assoc PF03828.14 KHN69490.1 - 1.8 8.5 6.9 19 5.3 4.8 2.5 1 1 0 1 1 1 0 Cid1 family poly A polymerase NDK PF00334.14 KHN69491.1 - 5.9e-50 168.5 0.0 6.8e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.27 KHN69493.1 - 5.4e-21 73.6 5.7 1.2e-07 31.3 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ PF01011.16 KHN69493.1 - 0.14 11.7 2.4 40 3.9 0.0 4.7 6 0 0 6 6 6 0 PQQ enzyme repeat ER_lumen_recept PF00810.13 KHN69495.1 - 9.5e-41 139.7 9.7 1.5e-40 139.0 6.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KHN69495.1 - 0.12 11.8 7.7 0.13 11.8 0.2 3.3 3 0 0 3 3 3 0 PQ loop repeat PSP1 PF04468.7 KHN69496.1 - 6.2e-30 103.0 2.9 9e-30 102.5 2.0 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region MAD PF05557.8 KHN69496.1 - 0.0034 15.5 0.5 0.0045 15.1 0.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF1469 PF07332.6 KHN69499.1 - 1.1 8.9 6.7 0.24 11.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) YwiC PF14256.1 KHN69499.1 - 1.9 8.6 7.0 1.5 8.9 3.0 2.0 1 1 1 2 2 2 0 YwiC-like protein DUF1129 PF06570.6 KHN69499.1 - 6.8 5.9 14.7 4.1 6.6 9.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DisA-linker PF10635.4 KHN69500.1 - 0.013 14.9 1.3 0.28 10.6 0.1 2.2 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region DUF3987 PF13148.1 KHN69500.1 - 0.023 13.3 0.1 0.028 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Alkyl_sulf_dimr PF14863.1 KHN69500.1 - 0.029 14.5 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation PPR_2 PF13041.1 KHN69500.1 - 0.063 13.2 1.3 0.29 11.1 0.1 2.5 3 1 0 3 3 3 0 PPR repeat family DALR_1 PF05746.10 KHN69500.1 - 0.086 12.7 0.2 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 DALR anticodon binding domain DUF1473 PF07341.6 KHN69500.1 - 0.28 10.7 3.1 0.55 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1473) DrrA_P4M PF14860.1 KHN69500.1 - 0.52 10.0 4.0 7.7 6.2 0.1 2.3 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain tRNA-synt_1d PF00750.14 KHN69500.1 - 1.5 7.5 6.3 0.97 8.1 0.3 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (R) DUF912 PF06024.7 KHN69502.1 - 0.047 13.7 1.0 0.047 13.7 0.7 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1772 PF08592.6 KHN69502.1 - 0.31 10.7 3.4 8.4 6.1 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF1461 PF07314.6 KHN69502.1 - 0.71 9.5 11.0 0.94 9.1 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) EII-GUT PF03608.8 KHN69502.1 - 1.5 8.6 11.0 1.6 8.5 1.4 2.2 2 0 0 2 2 2 0 PTS system enzyme II sorbitol-specific factor Acetyltransf_1 PF00583.19 KHN69503.1 - 3.9e-13 49.2 0.0 7.5e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KHN69503.1 - 4.1e-09 36.4 0.5 1e-08 35.1 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KHN69503.1 - 3.2e-06 27.2 0.0 8.6e-06 25.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KHN69503.1 - 3.8e-05 23.3 0.1 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KHN69503.1 - 0.0015 18.4 0.1 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KHN69503.1 - 0.043 13.7 2.0 0.051 13.5 0.2 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KHN69503.1 - 0.044 13.9 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TRAUB PF08164.7 KHN69504.1 - 0.00042 20.3 0.9 0.0012 18.9 0.0 2.2 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal DUF3418 PF11898.3 KHN69504.1 - 0.0024 16.3 0.6 0.0029 16.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) MRP-L28 PF09812.4 KHN69504.1 - 0.015 15.1 0.6 0.023 14.5 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF745 PF05335.8 KHN69504.1 - 0.078 12.5 0.6 0.11 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Synaptonemal_3 PF15191.1 KHN69504.1 - 0.093 12.4 1.2 0.15 11.8 0.7 1.6 1 1 0 1 1 1 0 Synaptonemal complex central element protein 3 Blo-t-5 PF11642.3 KHN69504.1 - 0.2 11.4 2.0 0.39 10.4 1.4 1.6 1 0 0 1 1 1 0 Mite allergen Blo t 5 ParB PF08775.5 KHN69504.1 - 0.26 11.6 2.7 0.51 10.6 0.9 2.2 1 1 1 2 2 2 0 ParB family DUF2310 PF10071.4 KHN69505.1 - 0.0045 15.9 0.1 0.0068 15.4 0.1 1.2 1 0 0 1 1 1 1 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) zf-C2H2_2 PF12756.2 KHN69505.1 - 0.045 13.8 0.2 0.074 13.1 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KHN69505.1 - 0.062 13.0 1.1 0.23 11.2 0.2 2.1 2 0 0 2 2 2 0 BED zinc finger DUF2197 PF09963.4 KHN69505.1 - 0.073 13.0 1.4 0.09 12.7 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Fer4_15 PF13459.1 KHN69505.1 - 0.12 12.9 0.0 0.92 10.1 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain Tim54 PF11711.3 KHN69506.1 - 0.094 11.2 0.1 0.094 11.2 0.0 2.0 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.1 KHN69506.1 - 0.38 11.0 4.3 0.27 11.5 1.7 1.7 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term AAA_21 PF13304.1 KHN69507.1 - 0.029 14.3 10.0 0.045 13.7 7.0 1.3 1 0 0 1 1 1 0 AAA domain 5_3_exonuc PF01367.15 KHN69507.1 - 0.04 14.1 0.4 0.04 14.1 0.3 2.8 4 0 0 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold DUF2975 PF11188.3 KHN69507.1 - 3.5 7.3 14.8 1.2 8.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF2463 PF09591.5 KHN69508.1 - 0.0051 16.4 16.6 0.0087 15.6 11.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Wzy_C PF04932.10 KHN69508.1 - 5.3 6.8 8.4 38 4.0 5.8 2.4 1 1 0 1 1 1 0 O-Antigen ligase MCPsignal PF00015.16 KHN69509.1 - 0.014 14.9 3.3 0.019 14.5 2.3 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF972 PF06156.8 KHN69509.1 - 0.029 14.7 0.6 0.044 14.1 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Imm5 PF14423.1 KHN69509.1 - 0.033 13.8 0.2 0.036 13.6 0.2 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 DUF3372 PF11852.3 KHN69509.1 - 0.086 11.9 0.8 0.099 11.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) FlaC_arch PF05377.6 KHN69509.1 - 0.12 12.3 4.6 2.7 7.9 0.4 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Sec8_exocyst PF04048.9 KHN69509.1 - 0.19 11.3 3.3 0.27 10.8 2.0 1.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain YolD PF08863.5 KHN69510.1 - 0.37 10.6 3.4 1.5 8.6 0.3 2.9 2 2 1 3 3 3 0 YolD-like protein Transketolase_N PF00456.16 KHN69511.1 - 4.7e-95 318.2 0.0 6.5e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KHN69511.1 - 2.1e-35 121.8 0.0 5.1e-35 120.5 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 KHN69511.1 - 0.0006 19.4 0.0 0.0073 15.8 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.15 KHN69511.1 - 0.0037 17.2 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KHN69511.1 - 0.0045 15.9 0.0 0.16 10.8 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DUF498 PF04430.9 KHN69511.1 - 0.11 11.9 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) E1_dh PF00676.15 KHN69511.1 - 0.12 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component zf-RING_2 PF13639.1 KHN69512.1 - 4.7e-12 45.5 2.7 4.7e-12 45.5 1.9 3.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KHN69512.1 - 4.5e-09 36.1 3.6 4.5e-09 36.1 2.5 3.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KHN69512.1 - 5e-08 32.4 1.7 5e-08 32.4 1.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69512.1 - 3.3e-07 29.9 2.5 3.3e-07 29.9 1.7 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KHN69512.1 - 3e-05 23.6 3.1 5.6e-05 22.7 0.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KHN69512.1 - 0.00013 21.9 3.9 0.00013 21.9 2.7 3.1 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KHN69512.1 - 0.00048 19.9 1.4 0.00048 19.9 1.0 3.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KHN69512.1 - 0.0036 16.7 0.9 0.0036 16.7 0.6 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 KHN69512.1 - 2.7 7.8 13.6 0.083 12.7 3.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KHN69512.1 - 2.9 8.0 11.6 0.25 11.4 1.5 2.9 2 1 0 2 2 2 0 RING-variant domain zf-RING_6 PF14835.1 KHN69512.1 - 5.7 6.8 13.7 0.067 12.9 0.7 3.5 4 0 0 4 4 4 0 zf-RING of BARD1-type protein TPR_1 PF00515.23 KHN69514.1 - 1.3e-11 43.5 9.8 3.8e-05 23.0 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KHN69514.1 - 1.2e-08 34.4 10.3 1.8e-05 24.2 0.0 4.2 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KHN69514.1 - 2.2e-07 30.2 17.3 0.0034 17.2 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KHN69514.1 - 2e-06 27.6 7.8 0.0026 17.6 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KHN69514.1 - 0.0016 18.8 0.0 4.1 8.3 0.0 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KHN69514.1 - 0.0023 18.2 0.8 1.2 9.5 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KHN69514.1 - 0.0031 17.1 16.9 0.094 12.5 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KHN69514.1 - 0.0062 16.2 0.4 0.25 11.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KHN69514.1 - 0.0082 16.7 1.1 1.7 9.4 0.0 3.2 4 0 0 4 4 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KHN69514.1 - 0.015 15.1 0.7 0.67 9.8 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 KHN69514.1 - 0.078 12.9 1.3 3.8 7.5 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF4116 PF13475.1 KHN69514.1 - 0.14 11.6 4.9 1.2 8.7 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) TPR_17 PF13431.1 KHN69514.1 - 0.54 10.5 4.8 45 4.6 0.0 5.1 6 1 0 6 6 6 0 Tetratricopeptide repeat Herpes_Helicase PF02689.9 KHN69515.1 - 0.14 9.8 0.6 0.16 9.7 0.4 1.0 1 0 0 1 1 1 0 Helicase Ax_dynein_light PF10211.4 KHN69515.1 - 1.3 8.7 13.8 1.5 8.5 9.6 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4116 PF13475.1 KHN69517.1 - 0.053 13.0 0.1 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) GHL5 PF14872.1 KHN69517.1 - 0.19 9.4 3.0 0.23 9.2 2.1 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Baculo_p24 PF05073.7 KHN69517.1 - 0.39 10.2 5.6 0.54 9.7 3.9 1.3 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF1664 PF07889.7 KHN69517.1 - 0.41 10.4 7.9 0.17 11.6 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3496 PF12001.3 KHN69517.1 - 0.51 10.6 5.3 1.4 9.2 0.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3496) Ran-binding PF05508.6 KHN69517.1 - 0.54 9.1 5.1 0.62 8.9 3.5 1.1 1 0 0 1 1 1 0 RanGTP-binding protein FliD_C PF07195.7 KHN69517.1 - 0.62 9.3 5.2 0.9 8.7 0.6 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2462 PF09495.5 KHN69517.1 - 0.73 10.6 6.4 5.3 7.8 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2462) Med9 PF07544.8 KHN69517.1 - 8.7 6.1 8.5 3.8 7.3 2.0 2.9 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PUF PF00806.14 KHN69518.1 - 3.1e-06 26.3 1.8 0.59 9.7 0.0 4.6 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat DnaA_N PF11638.3 KHN69518.1 - 0.22 11.1 1.7 9.9 5.8 0.3 3.1 3 0 0 3 3 3 0 DnaA N-terminal domain DUF1242 PF06842.7 KHN69519.1 - 2.3e-08 33.3 0.1 3.5e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) ATP-synt_C PF00137.16 KHN69522.1 - 3.4e-14 52.5 15.2 4.3e-08 32.9 2.6 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Helicase_C_2 PF13307.1 KHN69523.1 - 3.7e-50 170.1 0.3 9.9e-48 162.2 0.0 2.3 2 0 0 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.10 KHN69523.1 - 1.7e-43 148.0 1.1 1.7e-43 148.0 0.7 1.7 2 0 0 2 2 2 1 DEAD_2 DUF1227 PF06777.6 KHN69523.1 - 6.6e-32 110.2 0.3 2.1e-31 108.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD PF00270.24 KHN69523.1 - 6.3e-05 22.5 0.0 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KHN69523.1 - 9.8e-05 22.2 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KHN69523.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KHN69523.1 - 0.0071 15.6 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 KHN69523.1 - 0.013 15.6 0.2 1.5 8.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 KHN69523.1 - 0.18 10.7 0.0 6.5 5.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) eIF-5_eIF-2B PF01873.12 KHN69524.1 - 8.1e-28 96.5 1.0 1.2e-27 95.9 0.7 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PrmA PF06325.8 KHN69524.1 - 0.12 11.4 0.2 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HEAT PF02985.17 KHN69525.1 - 0.032 14.2 2.7 1.6 8.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat RRM_1 PF00076.17 KHN69526.1 - 3.1e-10 39.5 0.3 8.8e-10 38.0 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69526.1 - 4.4e-08 32.8 0.1 1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69526.1 - 5.2e-08 32.7 0.0 8.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4057 PF13266.1 KHN69526.1 - 0.031 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) Collagen PF01391.13 KHN69528.1 - 0.56 9.7 4.5 4.5 6.9 0.1 3.4 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) E2F_TDP PF02319.15 KHN69529.1 - 3.5e-17 61.7 0.5 1e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.5 KHN69529.1 - 1e-10 41.4 2.6 1.7e-10 40.7 1.8 1.4 1 0 0 1 1 1 1 Transcription factor DP GDA1_CD39 PF01150.12 KHN69529.1 - 0.019 13.5 0.5 0.026 13.0 0.2 1.3 1 1 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Cdc6_C PF09079.6 KHN69529.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal YopX PF09643.5 KHN69529.1 - 0.28 11.1 4.8 1.1 9.1 3.3 2.0 1 1 0 1 1 1 0 YopX protein Sybindin PF04099.7 KHN69530.1 - 5.8e-16 58.4 0.8 7.8e-16 58.0 0.6 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KHN69530.1 - 3.3e-06 27.0 0.4 4.5e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NADHdh-2_N PF12155.3 KHN69530.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal tRNA-synt_1g PF09334.6 KHN69531.1 - 2.7e-23 82.2 0.4 1.6e-10 40.2 0.2 3.2 2 2 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KHN69531.1 - 1.3e-20 72.9 0.1 1e-11 43.6 0.0 3.1 3 0 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KHN69531.1 - 4.2e-09 35.9 0.1 2.1e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-CCCH PF00642.19 KHN69532.1 - 0.12 12.0 11.1 1.4 8.6 1.0 3.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Paramecium_SA PF01508.11 KHN69532.1 - 2 8.6 23.8 0.082 13.1 9.6 2.7 2 1 0 2 2 2 0 Paramecium surface antigen domain Peptidase_U35_2 PF14550.1 KHN69533.1 - 0.1 12.2 0.5 5.5 6.6 0.0 2.9 2 0 0 2 2 2 0 Putative phage protease XkdF TGT PF01702.13 KHN69534.1 - 4.1e-83 278.3 0.1 5.4e-83 277.9 0.1 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RNA_pol_N PF01194.12 KHN69535.1 - 8.9e-28 96.1 1.2 1.1e-27 95.8 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KHN69535.1 - 0.00097 19.1 0.5 0.0013 18.7 0.3 1.3 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.1 KHN69535.1 - 0.0097 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 YhfH-like protein Rotamase PF00639.16 KHN69536.1 - 1.9e-20 73.3 0.0 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KHN69536.1 - 2.3e-14 53.6 0.0 3.3e-14 53.1 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KHN69536.1 - 1.3e-05 25.7 0.0 1.6e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KHN69536.1 - 0.064 13.1 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 WW domain MCM PF00493.18 KHN69537.1 - 2.1e-137 457.4 0.5 3e-137 456.8 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KHN69537.1 - 1.6e-13 51.2 0.2 5.8e-13 49.3 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KHN69537.1 - 1.3e-08 34.2 0.1 3.2e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 KHN69537.1 - 4.5e-05 23.7 0.3 0.00013 22.2 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KHN69537.1 - 0.00016 21.2 0.0 0.0008 19.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN69537.1 - 0.00018 21.2 0.0 0.0005 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TFIIE_beta PF02186.10 KHN69538.1 - 1.4e-06 28.1 1.6 1.4e-06 28.1 1.1 1.7 2 0 0 2 2 2 1 TFIIE beta subunit core domain tRNA_anti-codon PF01336.20 KHN69539.1 - 4.3e-09 36.1 0.0 7.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 KHN69539.1 - 1.3e-05 25.4 0.2 5.6e-05 23.4 0.1 2.0 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti_2 PF13742.1 KHN69539.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Imm35 PF15581.1 KHN69540.1 - 0.0057 16.6 0.3 2 8.5 0.0 3.0 2 0 0 2 2 2 2 Immunity protein 35 Reprolysin_3 PF13582.1 KHN69541.1 - 6.4e-05 23.4 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KHN69541.1 - 0.00017 21.5 0.0 0.00033 20.6 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin PF01421.14 KHN69541.1 - 0.00073 19.1 1.9 0.00084 18.9 0.0 2.0 3 0 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Peptidase_M10 PF00413.19 KHN69541.1 - 0.0031 17.2 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 KHN69541.1 - 0.0066 16.5 0.3 0.014 15.4 0.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 KHN69541.1 - 0.0093 15.3 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 KHN69541.1 - 0.022 14.3 1.2 0.035 13.6 0.3 1.8 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4215 PF13948.1 KHN69541.1 - 0.031 14.4 4.6 0.031 14.4 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4215) RNase_PH PF01138.16 KHN69542.1 - 0.0086 16.3 0.1 0.058 13.7 0.1 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RIO1 PF01163.17 KHN69543.1 - 8.5e-15 54.5 0.2 1.2e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KHN69543.1 - 8.9e-09 34.8 0.9 1.2e-08 34.4 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KHN69543.1 - 1e-07 31.2 0.0 4.5e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KHN69543.1 - 1.3e-07 31.5 0.0 1.8e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KHN69543.1 - 4.2e-06 26.0 0.3 5.7e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.15 KHN69543.1 - 7.9e-05 21.9 0.1 9.8e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.6 KHN69543.1 - 0.00031 20.0 1.8 0.00039 19.7 1.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.15 KHN69543.1 - 0.011 15.2 0.1 0.83 9.1 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase PI-PLC-X PF00388.14 KHN69543.1 - 0.065 12.6 0.2 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain CAP_GLY PF01302.20 KHN69544.1 - 6e-24 83.5 0.5 1.1e-23 82.6 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain THOC7 PF05615.8 KHN69544.1 - 0.026 14.7 0.6 0.035 14.3 0.4 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 MscS_porin PF12795.2 KHN69544.1 - 0.12 11.7 2.5 0.17 11.2 1.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Shugoshin_N PF07558.6 KHN69544.1 - 0.34 10.6 2.9 2.5 7.8 2.2 2.2 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF663 PF04950.7 KHN69546.1 - 9.2e-60 202.1 1.8 9.2e-60 202.1 1.2 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KHN69546.1 - 9.5e-15 53.9 0.2 1.3e-13 50.2 0.1 2.9 1 1 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KHN69546.1 - 0.00036 20.0 5.2 0.007 15.8 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KHN69546.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 KHN69546.1 - 0.0031 17.0 0.2 0.0098 15.4 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KHN69546.1 - 0.0065 16.4 0.2 0.046 13.6 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 KHN69546.1 - 0.023 14.3 0.1 0.023 14.3 0.1 2.3 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KHN69546.1 - 0.042 13.2 0.9 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 KHN69546.1 - 0.056 13.3 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KHN69546.1 - 0.061 13.8 0.2 0.061 13.8 0.2 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KHN69546.1 - 0.061 13.5 0.0 0.061 13.5 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) dUTPase PF00692.14 KHN69547.1 - 3.1e-28 97.8 0.0 3.5e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase DUF3594 PF12165.3 KHN69547.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3594) Lactamase_B_2 PF12706.2 KHN69548.1 - 3.1e-30 105.1 1.0 4.8e-30 104.5 0.7 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KHN69548.1 - 1.7e-13 50.6 0.0 3.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 KHN69548.1 - 3.1e-08 32.9 0.0 4.1e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 tRNase Z endonuclease PDEase_II PF02112.10 KHN69548.1 - 0.011 14.7 0.2 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II eIF2A PF08662.6 KHN69549.1 - 2.5e-05 24.0 3.3 0.00012 21.8 0.5 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A SPRY PF00622.23 KHN69549.1 - 0.013 15.6 0.1 0.068 13.2 0.1 2.3 2 0 0 2 2 2 0 SPRY domain DUF3294 PF07957.6 KHN69549.1 - 0.11 12.0 4.1 5 6.5 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3294) Acetyltransf_1 PF00583.19 KHN69550.1 - 6.4e-10 38.9 0.1 1e-08 35.0 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KHN69550.1 - 5.8e-05 23.1 0.0 0.00056 20.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KHN69550.1 - 9.2e-05 22.1 0.1 0.075 12.8 0.0 2.3 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.1 KHN69550.1 - 0.00048 20.2 2.2 0.0014 18.7 1.5 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KHN69550.1 - 0.039 13.8 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3626 PF12294.3 KHN69550.1 - 0.095 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Nucleoporin_N PF08801.6 KHN69551.1 - 7.9e-13 47.9 0.2 1.5e-12 47.0 0.1 1.4 1 1 0 1 1 1 1 Nup133 N terminal like Porin_3 PF01459.17 KHN69552.1 - 1.5e-26 93.3 0.0 1.7e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Cpn60_TCP1 PF00118.19 KHN69553.1 - 7.3e-104 348.0 3.9 1.5e-103 346.9 2.7 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family ThiF PF00899.16 KHN69554.1 - 0.03 14.1 0.1 0.27 11.0 0.0 2.5 2 1 0 2 2 2 0 ThiF family Tub PF01167.13 KHN69555.1 - 1.1e-35 122.8 0.1 1.5e-27 96.1 0.0 3.1 1 1 1 2 2 2 2 Tub family Sel1 PF08238.7 KHN69556.1 - 9.3e-26 89.6 9.6 2.4e-05 24.7 0.0 7.1 7 0 0 7 7 7 5 Sel1 repeat MIT PF04212.13 KHN69556.1 - 0.17 11.8 3.5 13 5.7 0.0 3.4 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain tRNA-synt_2e PF02091.10 KHN69557.1 - 0.092 11.8 0.1 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit CobN-Mg_chel PF02514.11 KHN69558.1 - 0.017 12.5 0.8 0.026 11.9 0.0 1.6 2 0 0 2 2 2 0 CobN/Magnesium Chelatase DUF3262 PF11660.3 KHN69559.1 - 1.1 9.3 12.8 0.098 12.7 0.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3262) DUF3366 PF11846.3 KHN69559.1 - 1.8 8.3 6.4 0.25 11.2 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Coatomer_b_Cpla PF14806.1 KHN69561.1 - 0.046 13.4 0.7 0.14 11.8 0.5 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Suf PF05843.9 KHN69561.1 - 0.14 11.8 0.1 0.14 11.8 0.1 3.8 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) RNA_pol_A_bac PF01000.21 KHN69562.1 - 1.6e-27 95.8 0.0 3.4e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KHN69562.1 - 4.4e-14 51.3 0.0 5.9e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 KHN69562.1 - 0.13 11.7 0.7 7.9 6.0 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb3/Rpb11 dimerisation domain MTS PF05175.9 KHN69563.1 - 3.2e-05 23.3 0.1 0.00014 21.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KHN69563.1 - 0.00023 21.1 0.0 0.00043 20.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN69563.1 - 0.0057 16.2 0.1 0.024 14.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain tRNA-synt_His PF13393.1 KHN69564.1 - 9.2e-41 139.8 0.0 1.1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KHN69564.1 - 2.4e-17 63.0 0.0 3.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KHN69564.1 - 2.4e-11 43.4 0.4 7.1e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2d PF01409.15 KHN69564.1 - 0.00047 19.4 0.0 0.0017 17.5 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) HGTP_anticodon2 PF12745.2 KHN69564.1 - 0.0025 17.0 0.1 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 KHN69564.1 - 0.013 14.2 0.5 0.084 11.6 0.1 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) ADK PF00406.17 KHN69566.1 - 8.9e-42 142.5 0.1 1.1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 KHN69566.1 - 3.7e-09 37.4 0.1 6.7e-09 36.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KHN69566.1 - 6.8e-08 32.8 0.2 1.5e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN69566.1 - 2.4e-07 30.7 0.0 7.3e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KHN69566.1 - 2.5e-07 30.2 0.1 0.012 15.0 0.0 2.0 1 1 1 2 2 2 2 Thymidylate kinase Cytidylate_kin2 PF13189.1 KHN69566.1 - 0.0022 17.9 0.4 1.9 8.3 0.2 2.1 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_24 PF13479.1 KHN69566.1 - 0.0027 17.3 0.0 0.0049 16.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.14 KHN69566.1 - 0.0037 17.1 0.2 0.0047 16.8 0.1 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase SKI PF01202.17 KHN69566.1 - 0.009 15.8 0.4 0.024 14.4 0.3 1.8 1 1 0 1 1 1 1 Shikimate kinase CoaE PF01121.15 KHN69566.1 - 0.016 14.6 0.2 0.19 11.0 0.2 2.0 1 1 1 2 2 2 0 Dephospho-CoA kinase ABC_tran PF00005.22 KHN69566.1 - 0.022 15.0 0.0 0.028 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PAS_7 PF12860.2 KHN69566.1 - 0.029 14.3 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 PAS fold 53-BP1_Tudor PF09038.5 KHN69567.1 - 0.0069 16.1 0.1 0.025 14.4 0.1 2.0 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor PH PF00169.24 KHN69568.1 - 9e-08 32.2 1.1 1.6e-07 31.4 0.8 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KHN69568.1 - 5.8e-05 23.3 5.0 5.8e-05 23.3 3.5 2.7 3 1 0 3 3 3 1 Pleckstrin homology domain Fibrinogen_aC PF12160.3 KHN69569.1 - 0.41 10.1 2.4 16 5.0 0.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha C domain Vac14_Fab1_bd PF12755.2 KHN69570.1 - 0.071 13.5 2.8 0.41 11.0 0.1 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RAI16-like PF10257.4 KHN69571.1 - 0.0088 15.0 0.2 1.8 7.3 0.0 2.3 2 0 0 2 2 2 2 Retinoic acid induced 16-like protein SF3b10 PF07189.6 KHN69571.1 - 0.18 11.6 0.8 30 4.5 0.0 2.8 3 0 0 3 3 3 0 Splicing factor 3B subunit 10 (SF3b10) FPL PF09758.4 KHN69571.1 - 1.9 8.2 9.5 1.8 8.3 0.3 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein PTPA PF03095.10 KHN69572.1 - 3.1e-47 161.1 3.6 5.5e-43 147.2 0.8 3.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein Ribonuc_red_sm PF00268.16 KHN69573.1 - 5.8e-110 366.7 2.1 6.8e-110 366.4 1.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF2384 PF09722.5 KHN69574.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Adaptin_N PF01602.15 KHN69575.1 - 1.6e-15 56.4 1.1 1.6e-15 56.4 0.8 2.4 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 KHN69575.1 - 0.00039 20.6 0.0 0.0026 17.9 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats Symplekin_C PF12295.3 KHN69576.1 - 4.2e-24 85.4 5.8 4.3e-24 85.4 2.5 2.3 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF1186 PF06685.6 KHN69576.1 - 0.002 17.3 1.0 0.002 17.3 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1186) tRNA-synt_2 PF00152.15 KHN69577.1 - 2.9e-70 236.6 0.1 3.8e-70 236.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KHN69577.1 - 5.2e-06 26.2 0.3 1.2e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KHN69577.1 - 0.059 12.5 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) CcmD PF04995.9 KHN69578.1 - 0.019 14.7 1.6 0.06 13.0 1.1 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4477 PF14780.1 KHN69579.1 - 1.5e-05 24.4 0.4 0.023 14.0 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) SNF2_N PF00176.18 KHN69580.1 - 1.9e-28 99.1 0.0 3.5e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KHN69580.1 - 2.9e-08 33.4 0.0 6.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69580.1 - 6e-07 29.4 0.0 6.8e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KHN69580.1 - 1.3e-05 24.7 0.1 6.1e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KHN69580.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RINGv PF12906.2 KHN69581.1 - 1.3e-13 50.7 7.0 1.3e-13 50.7 4.8 2.1 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KHN69581.1 - 0.16 11.8 6.1 0.47 10.3 4.2 1.9 1 0 0 1 1 1 0 Ring finger domain Ssu72 PF04722.8 KHN69582.1 - 3e-61 206.1 0.3 3.2e-61 206.0 0.2 1.0 1 0 0 1 1 1 1 Ssu72-like protein GTP_EFTU_D2 PF03144.20 KHN69583.1 - 0.087 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 FHA PF00498.21 KHN69584.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Sec63 PF02889.11 KHN69585.1 - 2.1e-12 46.9 0.0 2.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KHN69585.1 - 1.1e-07 31.4 0.1 2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3837 PF12939.2 KHN69585.1 - 0.0029 17.5 0.6 1.4 8.9 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3837) Spore_YhcN_YlaJ PF09580.5 KHN69585.1 - 7.7 6.5 12.3 0.23 11.5 1.1 3.1 3 1 1 4 4 4 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cullin PF00888.17 KHN69586.1 - 9.8e-15 54.1 18.8 2.3e-14 52.8 13.0 1.5 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KHN69586.1 - 5.8e-06 26.0 0.6 5.6e-05 22.8 0.3 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 KHN69586.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Penicillinase repressor TRP PF06011.7 KHN69587.1 - 0.0037 15.9 0.2 0.0043 15.6 0.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Arg_repressor_C PF02863.13 KHN69587.1 - 0.067 12.6 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Form-deh_trans PF09163.6 KHN69587.1 - 0.44 10.0 2.3 0.51 9.8 0.1 1.9 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Ribosomal_L18p PF00861.17 KHN69588.1 - 3.1e-31 108.0 0.5 3.1e-31 108.0 0.3 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KHN69588.1 - 2.5e-26 92.0 7.6 2.5e-26 92.0 5.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Lsr2 PF11774.3 KHN69588.1 - 0.11 12.4 4.5 0.93 9.4 0.1 2.5 2 0 0 2 2 2 0 Lsr2 UCH PF00443.24 KHN69589.1 - 3.5e-46 157.5 0.1 5.8e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KHN69589.1 - 4.5e-11 42.7 0.6 0.0034 16.8 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Sec63 PF02889.11 KHN69590.1 - 2.8e-27 95.7 0.1 4.4e-18 65.5 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KHN69590.1 - 1.3e-26 93.0 0.0 1.3e-25 89.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69590.1 - 3.1e-09 36.5 0.1 8.8e-09 35.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69590.1 - 1.5e-05 24.9 0.0 4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KHN69590.1 - 0.01 15.9 1.7 0.069 13.2 0.4 2.8 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.18 KHN69590.1 - 0.016 14.0 0.0 0.033 12.9 0.0 1.6 1 0 0 1 1 1 0 SNF2 family N-terminal domain T2SE PF00437.15 KHN69590.1 - 0.026 13.4 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Hydrolase PF00702.21 KHN69591.1 - 3.3e-19 70.1 0.0 2.5e-15 57.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 KHN69591.1 - 2.3e-17 63.7 0.1 4.3e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KHN69591.1 - 4.4e-16 58.6 2.5 8.5e-16 57.6 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KHN69591.1 - 1.6e-06 27.9 0.0 2e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KHN69591.1 - 0.0001 21.9 0.1 0.00087 18.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PMT PF02366.13 KHN69592.1 - 0.00013 21.4 11.9 0.00013 21.4 8.2 3.3 2 2 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase BTD PF09270.5 KHN69592.1 - 0.04 13.6 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Guanylate_cyc PF00211.15 KHN69593.1 - 6.1e-09 35.4 0.0 9.6e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FYRN PF05964.9 KHN69594.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 F/Y-rich N-terminus Nrap PF03813.9 KHN69595.1 - 0.051 11.1 0.0 4.9 4.5 0.0 2.3 2 1 0 2 2 2 0 Nrap protein Cpn60_TCP1 PF00118.19 KHN69596.1 - 1.3e-133 446.1 6.8 1.6e-133 445.8 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 KHN69596.1 - 0.043 13.6 0.4 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Resolvase, N terminal domain Zn_peptidase PF04228.8 KHN69596.1 - 0.1 11.8 0.1 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Herpes_UL92 PF03048.9 KHN69597.1 - 0.071 12.6 1.0 0.53 9.8 0.3 2.1 1 1 1 2 2 2 0 UL92 family Pkinase PF00069.20 KHN69598.1 - 1.8e-26 92.8 0.0 2.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69598.1 - 8.3e-15 54.5 0.0 1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69598.1 - 0.12 11.3 0.0 11 4.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like AAA PF00004.24 KHN69599.1 - 1.6e-46 157.7 0.0 3.1e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN69599.1 - 1.6e-08 34.3 0.1 5.1e-08 32.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KHN69599.1 - 2e-08 34.3 0.0 5.6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KHN69599.1 - 7.6e-07 29.2 0.1 3.4e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KHN69599.1 - 9.4e-07 29.0 0.6 5.9e-05 23.2 0.4 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KHN69599.1 - 4.6e-05 22.4 0.0 7.5e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 KHN69599.1 - 5.9e-05 22.8 0.1 0.00049 19.8 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 KHN69599.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN69599.1 - 0.00029 21.6 0.0 0.0007 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KHN69599.1 - 0.00033 19.7 0.0 0.00074 18.6 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KHN69599.1 - 0.00055 19.6 0.1 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KHN69599.1 - 0.00071 19.0 1.2 0.048 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KHN69599.1 - 0.00071 19.5 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN69599.1 - 0.00091 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KHN69599.1 - 0.00098 19.2 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 KHN69599.1 - 0.0018 17.9 0.0 0.0043 16.6 0.0 1.7 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KHN69599.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KHN69599.1 - 0.0028 17.2 0.0 0.008 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KHN69599.1 - 0.0031 16.6 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 KHN69599.1 - 0.0037 16.9 0.1 0.043 13.4 0.0 2.3 1 1 1 2 2 2 1 Archaeal ATPase NACHT PF05729.7 KHN69599.1 - 0.0038 16.8 0.1 0.048 13.3 0.0 2.2 1 1 1 2 2 2 1 NACHT domain AAA_18 PF13238.1 KHN69599.1 - 0.0041 17.4 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KHN69599.1 - 0.0042 15.8 0.0 0.014 14.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 KHN69599.1 - 0.0047 16.1 0.1 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KHN69599.1 - 0.0063 16.0 0.1 0.088 12.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KHN69599.1 - 0.0063 15.9 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.1 KHN69599.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KHN69599.1 - 0.0069 15.9 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KHN69599.1 - 0.0085 14.9 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KHN69599.1 - 0.03 14.6 0.1 0.1 12.9 0.0 2.0 2 1 0 2 2 1 0 ABC transporter Bac_DnaA PF00308.13 KHN69599.1 - 0.034 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 KHN69599.1 - 0.12 11.2 0.0 0.3 9.9 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 KHN69599.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF465 PF04325.8 KHN69599.1 - 0.31 10.7 2.6 0.72 9.6 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Dna2 PF08696.6 KHN69600.1 - 0.013 14.8 1.2 0.018 14.3 0.7 1.4 1 1 0 1 1 1 0 DNA replication factor Dna2 Adenine_glyco PF03352.8 KHN69600.1 - 0.027 14.0 2.3 0.038 13.5 1.6 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase ATP-synt_D PF01813.12 KHN69601.1 - 6.5e-54 182.4 4.3 7.4e-54 182.2 3.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.1 KHN69601.1 - 0.00035 19.8 2.1 0.00078 18.7 1.5 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FliL PF03748.9 KHN69601.1 - 0.025 14.5 0.3 0.025 14.5 0.2 1.6 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL HALZ PF02183.13 KHN69601.1 - 0.031 14.0 1.0 0.092 12.4 0.7 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.17 KHN69601.1 - 0.11 12.5 2.7 0.11 12.5 0.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_S13 PF00416.17 KHN69601.1 - 0.22 12.0 1.1 0.32 11.4 0.1 1.8 2 1 0 2 2 2 0 Ribosomal protein S13/S18 DUF4187 PF13821.1 KHN69602.1 - 4.5e-06 26.1 5.1 0.0031 17.0 1.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4187) ARS2 PF04959.8 KHN69602.1 - 4e-05 23.9 2.8 6.7e-05 23.1 1.9 1.3 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Rad50_zn_hook PF04423.9 KHN69602.1 - 0.0024 17.2 3.7 0.0024 17.2 2.5 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif PyrI_C PF02748.10 KHN69602.1 - 0.0029 17.0 2.3 0.011 15.1 1.6 2.0 1 0 0 1 1 1 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 KHN69602.1 - 0.0051 16.9 0.9 0.012 15.6 0.6 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 KHN69602.1 - 0.029 14.0 1.4 0.11 12.2 0.9 2.0 1 0 0 1 1 1 0 XPA protein N-terminal zf-H2C2_2 PF13465.1 KHN69602.1 - 0.043 14.1 0.4 0.16 12.3 0.3 2.0 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.21 KHN69602.1 - 0.1 12.9 1.8 0.31 11.4 1.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-CHC2 PF01807.15 KHN69602.1 - 0.42 10.1 5.6 5.1 6.7 0.6 2.4 2 0 0 2 2 2 0 CHC2 zinc finger zf-C2H2_2 PF12756.2 KHN69602.1 - 3 7.9 11.5 11 6.2 6.0 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KHN69602.1 - 9.9 6.4 10.3 1.1 9.5 2.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Ribosomal_L23 PF00276.15 KHN69603.1 - 4.5e-14 52.1 2.1 1.4e-13 50.5 1.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 Peptidase_M49 PF03571.10 KHN69603.1 - 0.062 11.3 0.2 0.065 11.2 0.1 1.0 1 0 0 1 1 1 0 Peptidase family M49 DUF1687 PF07955.6 KHN69603.1 - 0.063 13.2 0.2 0.069 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) SRP54 PF00448.17 KHN69604.1 - 1.7e-51 174.4 0.1 2.7e-51 173.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 KHN69604.1 - 3.2e-07 29.9 1.6 9.5e-07 28.4 0.2 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KHN69604.1 - 2.1e-05 23.4 0.1 6.7e-05 21.7 0.0 1.8 2 1 0 2 2 2 1 ArgK protein SRP54_N PF02881.14 KHN69604.1 - 0.00024 21.1 0.6 0.00093 19.2 0.4 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 KHN69604.1 - 0.00032 20.8 0.1 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KHN69604.1 - 0.0011 18.6 0.0 0.0044 16.7 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KHN69604.1 - 0.0018 17.7 0.1 0.0059 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_30 PF13604.1 KHN69604.1 - 0.002 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KHN69604.1 - 0.0021 18.2 0.1 0.097 12.8 0.0 2.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) VirC1 PF07015.6 KHN69604.1 - 0.0028 16.7 0.0 0.0066 15.5 0.0 1.5 1 1 0 1 1 1 1 VirC1 protein MMR_HSR1 PF01926.18 KHN69604.1 - 0.0029 17.5 0.1 0.0085 16.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 KHN69604.1 - 0.003 17.2 0.1 0.15 11.7 0.1 2.5 1 1 0 1 1 1 1 NTPase cobW PF02492.14 KHN69604.1 - 0.0034 16.8 1.7 0.02 14.3 1.2 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KHN69604.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KHN69604.1 - 0.092 12.1 0.1 0.41 10.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain Rib_5-P_isom_A PF06026.9 KHN69605.1 - 4.2e-38 130.3 0.0 4.9e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KHN69605.1 - 0.016 14.8 0.5 0.65 9.6 0.1 2.2 1 1 1 2 2 2 0 DeoR C terminal sensor domain DUF2683 PF10884.3 KHN69605.1 - 0.083 12.8 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) RPN7 PF10602.4 KHN69606.1 - 2.9e-31 108.2 0.2 5.7e-31 107.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KHN69606.1 - 3.7e-13 49.6 0.1 9.2e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KHN69606.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Nop PF01798.13 KHN69607.1 - 9e-07 28.3 0.0 2.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain RNA_pol_Rpc34 PF05158.7 KHN69608.1 - 1.4e-47 162.5 2.0 1.6e-47 162.2 1.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 KHN69608.1 - 0.00084 19.7 0.0 0.39 11.1 0.0 2.9 3 0 0 3 3 3 2 Replication protein A C terminal TrmB PF01978.14 KHN69608.1 - 0.042 13.5 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 KHN69608.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DUF433 PF04255.9 KHN69608.1 - 0.11 11.9 0.0 0.5 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF433) WD40 PF00400.27 KHN69609.1 - 2.8e-16 58.6 10.7 0.00093 18.9 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 KHN69609.1 - 0.00083 18.8 0.0 0.0039 16.6 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 KHN69609.1 - 0.0024 17.5 0.2 1.6 8.4 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Kelch_4 PF13418.1 KHN69609.1 - 0.26 11.1 2.3 7 6.5 0.1 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Tcp10_C PF07202.8 KHN69610.1 - 2.4e-05 23.9 1.0 3.9e-05 23.2 0.6 1.5 1 1 0 1 1 1 1 T-complex protein 10 C-terminus CENP-K PF11802.3 KHN69610.1 - 0.037 13.2 0.4 0.039 13.2 0.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K Not3 PF04065.10 KHN69610.1 - 0.057 12.6 2.7 0.076 12.2 1.9 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component YycI PF09648.5 KHN69610.1 - 0.068 12.6 2.2 0.079 12.3 1.5 1.1 1 0 0 1 1 1 0 YycH protein Pox_L5 PF04872.8 KHN69610.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus L5 protein family Dockerin_1 PF00404.13 KHN69610.1 - 0.28 10.9 2.0 14 5.5 0.0 2.8 3 0 0 3 3 3 0 Dockerin type I repeat Cpn60_TCP1 PF00118.19 KHN69611.1 - 9e-133 443.4 11.4 1e-132 443.2 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpb2_6 PF00562.23 KHN69612.1 - 4.1e-129 430.6 0.0 6.1e-129 430.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KHN69612.1 - 1.9e-61 206.5 0.2 3.7e-61 205.6 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KHN69612.1 - 8.9e-43 145.9 0.0 1.4e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KHN69612.1 - 5.5e-30 103.4 0.0 5.7e-29 100.2 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 KHN69612.1 - 1.5e-25 88.6 0.0 3e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KHN69612.1 - 2.1e-23 81.8 0.2 7.3e-23 80.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KHN69612.1 - 5.7e-16 58.2 1.9 8.5e-16 57.6 0.4 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 CBFD_NFYB_HMF PF00808.18 KHN69613.1 - 8e-21 73.8 4.7 1e-20 73.5 3.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KHN69613.1 - 0.0016 18.5 0.1 0.0026 17.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KHN69613.1 - 0.011 15.3 0.1 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 Bromodomain associated CENP-X PF09415.5 KHN69613.1 - 0.058 13.2 0.2 0.073 12.9 0.2 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X RNase_PH PF01138.16 KHN69614.1 - 4.1e-14 53.0 0.1 1e-13 51.7 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 GNAT_acetyltr_2 PF13718.1 KHN69615.1 - 1.2e-52 178.1 0.0 2.1e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KHN69615.1 - 1.3e-51 174.7 0.1 3.6e-51 173.2 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KHN69615.1 - 1.1e-24 85.8 1.6 1.2e-23 82.5 0.0 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KHN69615.1 - 2.6e-10 40.3 0.9 6.6e-10 39.0 0.1 2.0 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 KHN69615.1 - 0.0011 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KHN69615.1 - 0.011 15.8 0.0 0.045 13.9 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-U1 PF06220.7 KHN69616.1 - 1.2e-13 50.3 2.0 1.6e-13 49.9 1.4 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-met PF12874.2 KHN69616.1 - 0.15 12.2 5.3 5 7.4 3.7 2.3 1 1 0 1 1 1 0 Zinc-finger of C2H2 type MBOAT PF03062.14 KHN69617.1 - 2.4e-17 63.0 27.9 3.5e-17 62.5 19.3 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KHN69617.1 - 7.3e-05 22.7 4.1 7.3e-05 22.7 2.8 2.7 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family Acyltransferase PF01553.16 KHN69618.1 - 9e-12 44.5 0.1 2.1e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 KHN69619.1 - 9.7e-95 317.0 3.7 9.7e-95 317.0 2.6 1.5 1 1 0 1 1 1 1 Kinesin motor domain AAA_17 PF13207.1 KHN69619.1 - 0.00053 20.7 0.3 0.0085 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain BLOC1_2 PF10046.4 KHN69619.1 - 0.02 15.0 6.1 0.043 13.9 3.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Zeta_toxin PF06414.7 KHN69619.1 - 0.033 13.3 0.0 0.11 11.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AKNA PF12443.3 KHN69619.1 - 0.045 13.7 1.9 0.58 10.1 0.8 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor rve_3 PF13683.1 KHN69619.1 - 0.069 12.6 2.2 1.5 8.3 0.0 3.3 3 1 0 3 3 3 0 Integrase core domain TMF_DNA_bd PF12329.3 KHN69619.1 - 0.12 12.2 5.2 0.42 10.4 3.1 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF87 PF01935.12 KHN69619.1 - 0.17 11.6 5.5 5.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KHN69619.1 - 1.9 8.7 13.5 1.5 9.1 3.3 3.2 3 0 0 3 3 3 0 AAA domain Pyrophosphatase PF00719.14 KHN69621.1 - 7.4e-46 155.4 0.4 9.3e-46 155.1 0.3 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Cut8_C PF08559.5 KHN69621.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cut8 six-helix bundle Ras PF00071.17 KHN69622.1 - 1e-50 171.2 0.0 1.2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN69622.1 - 2.4e-13 50.6 0.0 4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN69622.1 - 5.2e-10 38.8 0.0 6.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN69622.1 - 2.8e-05 23.3 0.0 3.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KHN69622.1 - 0.0015 18.0 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SH3BP5 PF05276.9 KHN69623.1 - 0.00037 19.8 1.0 0.00045 19.6 0.7 1.0 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF4602 PF15375.1 KHN69623.1 - 0.037 14.0 4.9 0.042 13.9 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) DUF1140 PF06600.6 KHN69623.1 - 0.56 10.3 3.1 3.7 7.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1140) Cofilin_ADF PF00241.15 KHN69624.1 - 7.7e-07 29.0 0.1 1.4e-06 28.2 0.1 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pox_MCEL PF03291.11 KHN69626.1 - 3.8e-53 180.5 4.5 7.2e-53 179.5 3.1 1.5 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 KHN69626.1 - 8.3e-13 48.1 0.0 1.7e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KHN69626.1 - 1.9e-11 43.9 0.0 3.5e-11 43.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KHN69626.1 - 2.6e-11 43.8 0.3 8e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KHN69626.1 - 3.4e-10 40.2 0.0 7.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KHN69626.1 - 5.6e-09 36.5 0.0 1.1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KHN69626.1 - 2.7e-07 30.8 0.1 8.7e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KHN69626.1 - 9.8e-06 25.5 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KHN69626.1 - 2.8e-05 23.3 0.2 3.7e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.12 KHN69626.1 - 0.0003 19.8 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 KHN69626.1 - 0.00077 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KHN69626.1 - 0.0012 18.0 0.1 0.002 17.2 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 KHN69626.1 - 0.0028 16.8 0.1 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CobU PF02283.11 KHN69626.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MetW PF07021.7 KHN69626.1 - 0.019 14.3 0.1 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 KHN69626.1 - 0.024 13.7 0.0 0.037 13.1 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sec5 PF15469.1 KHN69627.1 - 8.5e-26 90.7 7.8 8.5e-26 90.7 5.4 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 DUF1788 PF08747.6 KHN69627.1 - 0.0062 16.3 1.1 0.027 14.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1788) DUF3781 PF12636.2 KHN69627.1 - 1 9.3 9.6 2.5 8.1 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Ribosom_S12_S23 PF00164.20 KHN69628.1 - 1.7e-32 111.3 0.8 2e-32 111.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ssl1 PF04056.9 KHN69629.1 - 0.0015 18.1 0.2 0.0019 17.8 0.1 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KHN69629.1 - 0.0017 18.5 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 KHN69629.1 - 0.0094 15.4 0.5 0.02 14.4 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Alba PF01918.16 KHN69629.1 - 0.093 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Alba TLC PF03219.9 KHN69630.1 - 9.2e-46 156.3 24.4 1.1e-45 156.0 16.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter RNA_pol_3_Rpc31 PF11705.3 KHN69631.1 - 0.016 15.1 0.1 0.016 15.1 0.1 2.1 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DEAD PF00270.24 KHN69632.1 - 9.5e-45 152.1 0.0 3.3e-44 150.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69632.1 - 1.4e-25 88.9 0.0 2.8e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 KHN69632.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 KHN69632.1 - 0.003 17.4 0.0 0.021 14.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3396 PF11876.3 KHN69632.1 - 0.047 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) AAA_19 PF13245.1 KHN69632.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF3638 PF12340.3 KHN69632.1 - 0.11 11.5 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) MS_channel PF00924.13 KHN69633.1 - 2.1e-18 66.4 1.7 4.3e-18 65.3 1.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel HIT PF01230.18 KHN69634.1 - 1.4e-17 64.0 0.1 2.2e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KHN69634.1 - 1.3e-06 28.6 0.3 2.3e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding phiKZ_IP PF12699.2 KHN69634.1 - 0.092 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins HECT_2 PF09814.4 KHN69635.1 - 3.1e-08 32.7 1.1 4.8e-08 32.0 0.8 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TLC PF03219.9 KHN69637.1 - 1.9e-44 152.0 29.0 2.3e-44 151.7 20.1 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter UDG PF03167.14 KHN69638.1 - 3.5e-25 88.2 0.0 6.1e-25 87.4 0.0 1.4 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily TLC PF03219.9 KHN69639.1 - 8.5e-55 186.1 31.3 1.1e-54 185.8 21.7 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter DUF1614 PF07758.6 KHN69639.1 - 0.0077 15.9 0.8 0.0077 15.9 0.6 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1614) Proteasome PF00227.21 KHN69640.1 - 1.2e-32 112.7 0.1 1.4e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN69640.1 - 5.4e-05 22.4 0.0 0.00012 21.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature adh_short PF00106.20 KHN69641.1 - 8.1e-14 51.8 0.1 6.2e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 KHN69641.1 - 1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KHN69641.1 - 4.9e-05 23.0 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 KHN69641.1 - 0.14 11.6 0.0 0.37 10.1 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.20 KHN69642.1 - 2e-26 92.7 0.0 2.9e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69642.1 - 3.3e-09 36.2 0.1 4.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN69642.1 - 0.00036 19.5 0.1 0.037 12.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like NIF PF03031.13 KHN69643.1 - 2.9e-10 40.0 0.2 5e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PI3_PI4_kinase PF00454.22 KHN69644.1 - 1e-16 61.1 0.1 5e-13 49.0 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Rep_fac-A_C PF08646.5 KHN69645.1 - 9.7e-53 177.7 4.5 9.6e-51 171.3 1.4 3.1 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 KHN69645.1 - 1.9e-15 56.4 3.0 2.2e-11 43.4 0.2 4.1 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 KHN69645.1 - 2.5e-11 43.2 0.1 7.2e-10 38.5 0.0 2.8 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain PRP38 PF03371.10 KHN69646.1 - 1.2e-21 77.1 0.4 1.5e-21 76.7 0.3 1.0 1 0 0 1 1 1 1 PRP38 family Ehbp PF10622.4 KHN69646.1 - 0.064 13.2 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) IBN_N PF03810.14 KHN69647.1 - 0.017 14.9 0.1 0.058 13.3 0.0 2.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain NotI PF12183.3 KHN69647.1 - 0.08 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NotI Cpn60_TCP1 PF00118.19 KHN69648.1 - 2.1e-128 429.0 0.1 2.3e-128 428.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_6 PF12774.2 KHN69649.1 - 1.5e-23 83.5 1.2 2.1e-14 53.6 0.5 2.9 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 KHN69649.1 - 1.8e-13 49.8 8.5 1.8e-13 49.8 5.9 4.3 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 KHN69649.1 - 1.5e-12 47.3 0.0 0.00018 21.2 0.0 5.3 5 0 0 5 5 5 2 AAA domain (dynein-related subfamily) MT PF12777.2 KHN69649.1 - 9e-09 34.5 6.1 1.8e-08 33.5 4.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.1 KHN69649.1 - 5e-08 33.1 0.0 0.0079 16.3 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 KHN69649.1 - 1.5e-05 25.2 0.3 0.63 10.2 0.0 5.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Laminin_II PF06009.7 KHN69649.1 - 0.0049 16.6 2.3 0.018 14.8 1.6 2.0 1 0 0 1 1 1 1 Laminin Domain II AAA_16 PF13191.1 KHN69649.1 - 0.005 16.8 0.0 52 3.7 0.0 4.4 4 0 0 4 4 4 0 AAA ATPase domain RNA_helicase PF00910.17 KHN69649.1 - 0.03 14.5 2.5 7.3 6.8 0.0 3.9 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 KHN69649.1 - 0.11 11.8 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KHN69649.1 - 0.13 11.7 0.0 1.5 8.2 0.0 2.7 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 KHN69649.1 - 0.19 11.2 0.0 17 5.0 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Med4 PF10018.4 KHN69649.1 - 0.23 10.8 1.1 0.56 9.5 0.7 1.6 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Cupin_6 PF12852.2 KHN69649.1 - 0.96 9.0 0.0 19 4.8 0.0 2.4 3 0 0 3 3 2 0 Cupin ABC_tran PF00005.22 KHN69649.1 - 3.2 8.0 6.1 61 3.9 0.0 4.8 5 0 0 5 5 5 0 ABC transporter MOZ_SAS PF01853.13 KHN69651.1 - 1.6e-74 249.2 1.8 2.3e-74 248.7 1.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KHN69651.1 - 4.8e-16 58.1 0.0 1.1e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain UPF0113 PF03657.8 KHN69652.1 - 1.2e-07 31.5 0.2 1.8e-07 30.9 0.1 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KHN69652.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 PUA domain Helicase_C PF00271.26 KHN69653.1 - 3.4e-12 46.0 0.5 6.6e-10 38.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.18 KHN69653.1 - 1.2e-10 41.2 0.1 4.6e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 KHN69653.1 - 3.8e-06 26.4 0.6 3.8e-06 26.4 0.4 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KHN69653.1 - 2.3e-05 24.5 0.7 9.7e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain OB_NTP_bind PF07717.11 KHN69653.1 - 0.00014 21.6 0.0 0.00066 19.4 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Flavi_DEAD PF07652.9 KHN69653.1 - 0.0038 17.0 0.1 0.0096 15.6 0.0 1.7 1 1 0 1 1 1 1 Flavivirus DEAD domain Viral_helicase1 PF01443.13 KHN69653.1 - 0.041 13.3 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KHN69653.1 - 0.053 13.3 3.4 2 8.2 0.0 4.2 4 1 0 5 5 5 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KHN69653.1 - 0.82 9.5 8.0 0.29 11.0 0.9 3.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 KHN69654.1 - 7.2e-38 129.7 0.2 1.5e-37 128.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69654.1 - 4e-20 71.4 0.0 8e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KHN69654.1 - 9.6e-09 34.6 0.0 1.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KHN69654.1 - 0.0001 22.1 0.0 0.00027 20.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KHN69654.1 - 0.00083 19.0 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 KHN69654.1 - 0.02 15.0 0.0 0.18 11.9 0.0 2.5 3 1 0 3 3 3 0 AAA domain MutS_V PF00488.16 KHN69656.1 - 7.8e-69 231.6 0.2 1.6e-68 230.6 0.2 1.6 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.15 KHN69656.1 - 4.6e-34 116.8 0.1 1.2e-33 115.4 0.1 1.8 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.13 KHN69656.1 - 3.1e-28 98.9 0.0 7.3e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KHN69656.1 - 1.1e-10 41.5 1.1 4.4e-10 39.6 0.8 2.1 1 0 0 1 1 1 1 MutS family domain IV Mre11_DNA_bind PF04152.9 KHN69656.1 - 0.012 15.5 0.4 0.012 15.5 0.3 2.2 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Bac_DnaA PF00308.13 KHN69658.1 - 0.034 13.7 0.2 0.041 13.5 0.2 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein Peptidase_M24 PF00557.19 KHN69659.1 - 1.5e-34 119.3 0.0 1.9e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PP1_inhibitor PF05361.7 KHN69659.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Peptidase_C41 PF05417.6 KHN69660.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease DUF3591 PF12157.3 KHN69661.1 - 1.1e-104 350.4 0.0 2.9e-103 345.7 0.0 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 KHN69661.1 - 6.9e-21 73.9 0.1 1.3e-19 69.8 0.0 2.6 2 0 0 2 2 2 1 Bromodomain zf-CCHC_6 PF15288.1 KHN69661.1 - 1.6e-06 27.6 2.8 3.1e-06 26.7 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Rep_fac_C PF08542.6 KHN69663.1 - 5.9e-17 61.4 0.4 1.4e-16 60.1 0.3 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KHN69663.1 - 3.7e-09 36.4 0.0 8.3e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 KHN69663.1 - 0.0031 17.0 0.0 0.0077 15.7 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KHN69663.1 - 0.0061 16.6 0.1 0.12 12.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 KHN69663.1 - 0.04 12.5 0.1 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AftA_C PF12249.3 KHN69663.1 - 0.14 11.5 0.0 6 6.2 0.0 2.2 1 1 1 2 2 2 0 Arabinofuranosyltransferase A C terminal Ada3 PF10198.4 KHN69664.1 - 0.00011 21.9 1.6 0.00011 21.9 1.1 1.7 1 1 1 2 2 2 1 Histone acetyltransferases subunit 3 SurA_N_2 PF13623.1 KHN69664.1 - 0.00016 21.7 1.5 0.00027 20.9 1.0 1.3 1 0 0 1 1 1 1 SurA N-terminal domain Chlam_vir PF05475.6 KHN69664.1 - 0.29 10.2 2.3 2.6 7.0 0.5 2.1 1 1 1 2 2 2 0 Chlamydia virulence protein PGP3-D Methyltransf_8 PF05148.10 KHN69665.1 - 3.7e-79 265.4 0.7 4.1e-79 265.2 0.5 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KHN69665.1 - 5e-08 33.3 0.1 3.1e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN69665.1 - 1.3e-05 24.8 0.1 0.0085 15.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KHN69665.1 - 0.024 13.7 0.1 0.21 10.6 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KHN69665.1 - 0.08 13.3 0.1 3.7 7.9 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain DUF1741 PF08427.5 KHN69666.1 - 0.062 12.7 0.3 0.099 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) Ndc80_HEC PF03801.8 KHN69667.1 - 1.6e-41 141.4 0.0 3.3e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Bunya_NS-S PF01104.12 KHN69667.1 - 0.034 13.6 0.4 0.06 12.8 0.3 1.3 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Fibrillarin PF01269.12 KHN69668.1 - 3.1e-105 350.1 0.0 3.7e-105 349.9 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KHN69668.1 - 0.021 14.3 0.0 0.021 14.3 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Ribosomal_L28e PF01778.12 KHN69669.1 - 1.5e-23 83.3 0.0 1.5e-23 83.3 0.0 2.3 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.9 KHN69669.1 - 6.1e-05 23.0 7.8 6.1e-05 23.0 5.4 1.8 2 0 0 2 2 2 1 Mak16 protein C-terminal region Med31 PF05669.7 KHN69669.1 - 0.0065 16.1 0.4 0.016 14.9 0.2 1.9 1 1 0 1 1 1 1 SOH1 Syntaxin PF00804.20 KHN69669.1 - 0.49 10.5 3.9 0.3 11.2 0.1 2.0 1 1 1 2 2 2 0 Syntaxin LUC7 PF03194.10 KHN69670.1 - 3.4e-25 89.0 8.6 7.6e-25 87.8 6.0 1.5 1 1 0 1 1 1 1 LUC7 N_terminus DUF3354 PF11834.3 KHN69670.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) Pentapeptide_4 PF13599.1 KHN69671.1 - 0.016 14.9 1.3 0.68 9.7 0.0 3.2 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 KHN69671.1 - 0.56 10.1 3.5 2.2 8.2 0.0 3.2 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) SieB PF14163.1 KHN69672.1 - 0.66 9.5 2.8 0.96 9.0 1.9 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF3185 PF11381.3 KHN69672.1 - 0.7 9.6 13.7 0.093 12.5 1.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3185) Herpes_LMP1 PF05297.6 KHN69672.1 - 0.74 8.6 7.7 0.77 8.6 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF872 PF05915.7 KHN69672.1 - 1.1 9.0 10.1 0.13 12.1 3.0 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF202 PF02656.10 KHN69672.1 - 1.8 8.8 9.9 12 6.1 6.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MMPL PF03176.10 KHN69672.1 - 4.3 5.9 6.1 6.3 5.4 4.2 1.2 1 0 0 1 1 1 0 MMPL family DAO PF01266.19 KHN69673.1 - 3.5e-41 141.3 0.0 4.6e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KHN69673.1 - 1.8e-07 30.3 4.7 0.00018 20.4 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 KHN69673.1 - 3.3e-06 26.4 1.7 3.3e-06 26.4 1.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KHN69673.1 - 0.00011 22.1 0.1 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KHN69673.1 - 0.0016 18.4 0.9 0.0059 16.6 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KHN69673.1 - 0.0018 16.8 0.4 0.0027 16.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KHN69673.1 - 0.002 18.4 0.3 0.0057 17.0 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KHN69673.1 - 0.0089 14.9 0.3 0.0089 14.9 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 KHN69673.1 - 0.009 15.1 0.1 0.009 15.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 KHN69673.1 - 0.19 10.6 0.9 0.25 10.1 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein RabGAP-TBC PF00566.13 KHN69674.1 - 5.3e-08 32.6 0.2 2e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain EssA PF10661.4 KHN69674.1 - 0.017 14.7 0.2 0.017 14.7 0.1 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA TAT_signal PF10518.4 KHN69674.1 - 0.024 14.6 0.3 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Methyltransf_12 PF08242.7 KHN69674.1 - 0.031 14.7 0.2 0.27 11.7 0.1 2.4 3 0 0 3 3 3 0 Methyltransferase domain Beta-Casp PF10996.3 KHN69675.1 - 3e-32 111.1 0.0 5.8e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KHN69675.1 - 1.5e-16 60.5 0.1 3.5e-16 59.4 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KHN69675.1 - 1.2e-12 47.7 0.6 2.3e-12 46.8 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KHN69675.1 - 4.8e-10 39.0 0.0 1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase CPSF73-100_C PF11718.3 KHN69675.1 - 3.8e-06 26.4 0.1 7.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_3 PF13483.1 KHN69675.1 - 3.2e-05 23.7 0.0 9.2e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain AMP-binding PF00501.23 KHN69676.1 - 7e-83 278.3 0.0 8.9e-83 277.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribonuc_red_lgC PF02867.10 KHN69677.1 - 1.1e-205 684.3 0.0 1.6e-205 683.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KHN69677.1 - 4.9e-20 71.1 0.1 1.5e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KHN69677.1 - 0.038 14.4 0.1 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain UQ_con PF00179.21 KHN69678.1 - 2.8e-46 156.4 0.1 3.3e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KHN69678.1 - 1.6e-07 31.0 0.0 2.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KHN69678.1 - 0.00093 19.0 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF295 PF03478.13 KHN69679.1 - 0.02 14.2 0.0 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF295) AAA_18 PF13238.1 KHN69680.1 - 2.4e-24 86.0 0.1 3.2e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN69680.1 - 1.3e-14 55.0 0.2 1.6e-14 54.7 0.1 1.2 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KHN69680.1 - 2.1e-05 24.4 0.1 3.1e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.10 KHN69680.1 - 0.00013 21.7 0.2 0.0003 20.5 0.2 1.6 1 0 0 1 1 1 1 NTPase ADK PF00406.17 KHN69680.1 - 0.00055 19.8 0.0 0.0089 15.9 0.0 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA PF00004.24 KHN69680.1 - 0.00066 19.8 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KHN69680.1 - 0.00094 19.0 0.0 0.0029 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 KHN69680.1 - 0.0018 17.8 0.9 0.0031 17.0 0.3 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 KHN69680.1 - 0.0022 18.1 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase GvpD PF07088.6 KHN69680.1 - 0.0027 16.1 0.1 0.0032 15.8 0.1 1.1 1 0 0 1 1 1 1 GvpD gas vesicle protein PRK PF00485.13 KHN69680.1 - 0.0031 17.0 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KHN69680.1 - 0.0054 16.7 0.4 0.0096 15.8 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KHN69680.1 - 0.0064 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KHN69680.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 KHN69680.1 - 0.013 14.8 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.1 KHN69680.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KHN69680.1 - 0.019 14.5 0.9 0.035 13.6 0.6 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KHN69680.1 - 0.026 14.2 0.5 0.084 12.5 0.2 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 KHN69680.1 - 0.028 14.1 0.0 0.058 13.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KHN69680.1 - 0.039 13.8 0.2 0.18 11.7 0.0 1.9 1 1 1 2 2 2 0 Cytidylate kinase-like family KaiC PF06745.8 KHN69680.1 - 0.045 12.8 1.8 0.12 11.5 0.2 2.1 1 1 0 2 2 2 0 KaiC SRP54 PF00448.17 KHN69680.1 - 0.13 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Citrate_synt PF00285.16 KHN69681.1 - 0.062 12.0 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Citrate synthase DUF3139 PF11337.3 KHN69681.1 - 0.071 13.3 0.2 0.071 13.3 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Ribosomal_L18e PF00828.14 KHN69683.1 - 7.9e-25 87.7 0.0 9.8e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Kinesin PF00225.18 KHN69684.1 - 4e-69 232.8 0.5 6.4e-69 232.2 0.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Caps_synth_GfcC PF06251.6 KHN69685.1 - 0.029 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC FYRN PF05964.9 KHN69686.1 - 2.6e-10 39.5 0.3 5.1e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 KHN69686.1 - 0.1 12.4 0.4 5 7.0 0.0 2.6 3 0 0 3 3 3 0 F/Y rich C-terminus CLASP_N PF12348.3 KHN69687.1 - 7e-08 32.1 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal DUF2667 PF10868.3 KHN69687.1 - 0.1 13.0 3.7 21 5.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2667) ATP-synt_ab PF00006.20 KHN69688.1 - 1.1e-60 204.8 0.0 1.4e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KHN69688.1 - 1.4e-15 57.7 0.0 2.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KHN69688.1 - 1.1e-10 41.5 1.5 2.3e-10 40.5 1.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DNA_RNApol_7kD PF03604.8 KHN69689.1 - 2e-10 39.9 5.6 2.4e-10 39.6 3.9 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 KHN69689.1 - 0.0029 17.0 1.6 0.67 9.4 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain NOB1_Zn_bind PF08772.6 KHN69689.1 - 0.0029 17.4 0.5 0.0034 17.1 0.4 1.1 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.5 KHN69689.1 - 0.017 15.0 1.2 0.026 14.4 0.8 1.4 1 1 0 1 1 1 0 Zinc ribbon domain HypA PF01155.14 KHN69689.1 - 0.02 14.5 0.8 0.021 14.5 0.6 1.0 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family T4_baseplate PF12322.3 KHN69689.1 - 0.023 13.9 0.4 0.023 13.9 0.3 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein zf-C2HC5 PF06221.8 KHN69689.1 - 0.092 12.5 0.7 0.18 11.6 0.4 1.5 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type NCD3G PF07562.9 KHN69689.1 - 0.098 12.3 0.4 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR TFIIS_C PF01096.13 KHN69689.1 - 0.098 12.3 2.2 5.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) C1_1 PF00130.17 KHN69689.1 - 0.16 11.7 0.7 0.2 11.3 0.5 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRN7 PF11781.3 KHN69689.1 - 0.33 10.4 2.3 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Metalloenzyme PF01676.13 KHN69691.1 - 3.2e-62 210.2 0.8 3.6e-62 210.0 0.5 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 KHN69691.1 - 4e-55 186.5 1.4 9.7e-55 185.3 1.0 1.5 1 1 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 KHN69691.1 - 2.9e-06 26.8 0.0 8.8e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KHN69691.1 - 4.8e-06 25.9 0.0 2e-05 23.9 0.0 1.7 1 1 0 2 2 2 1 Sulfatase PglZ PF08665.7 KHN69691.1 - 0.087 12.4 0.1 1.6 8.3 0.0 3.0 4 0 0 4 4 4 0 PglZ domain Ribosomal_60s PF00428.14 KHN69692.1 - 3.5e-09 36.9 4.8 4.1e-09 36.7 3.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DNA_pol_E_B PF04042.11 KHN69693.1 - 6.4e-26 90.8 0.0 1.3e-25 89.8 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B PHD PF00628.24 KHN69694.1 - 1.5e-07 30.9 9.6 4e-07 29.6 6.7 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KHN69694.1 - 0.021 14.1 5.2 0.082 12.2 3.6 2.1 1 0 0 1 1 1 0 PHD-finger RNase_PH PF01138.16 KHN69694.1 - 0.03 14.6 0.0 0.041 14.1 0.0 1.4 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 DUF2730 PF10805.3 KHN69694.1 - 0.072 12.8 0.3 0.13 11.9 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) CorA PF01544.13 KHN69694.1 - 0.18 10.8 0.7 0.24 10.4 0.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DnaJ PF00226.26 KHN69695.1 - 4.5e-19 67.9 0.7 8e-19 67.1 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain YARHG PF13308.1 KHN69695.1 - 0.014 14.9 0.4 0.037 13.5 0.2 1.7 1 0 0 1 1 1 0 YARHG domain DUF3364 PF11844.3 KHN69695.1 - 0.23 11.4 3.3 0.23 11.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) RRM_1 PF00076.17 KHN69696.1 - 5.6e-56 186.0 10.0 1.3e-16 59.9 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69696.1 - 5.7e-51 170.3 2.7 2.3e-13 49.9 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69696.1 - 2.8e-31 107.1 8.5 4.5e-07 29.6 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KHN69696.1 - 1.3e-07 31.4 0.0 1 9.3 0.0 4.1 4 0 0 4 4 4 3 RNA binding domain Nup35_RRM_2 PF14605.1 KHN69696.1 - 2e-07 30.6 0.1 0.1 12.3 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KHN69696.1 - 0.00051 19.8 4.7 0.0044 16.8 0.1 3.6 4 0 0 4 4 4 1 RNA binding motif RRM_2 PF04059.7 KHN69696.1 - 0.11 12.5 0.8 12 5.9 0.1 2.9 2 0 0 2 2 2 0 RNA recognition motif 2 DUF1546 PF07571.8 KHN69697.1 - 7.4e-20 70.8 0.0 1.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 KHN69697.1 - 2e-19 69.2 0.0 5e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF3554 PF12074.3 KHN69697.1 - 0.0092 15.4 1.1 0.029 13.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3554) CBFD_NFYB_HMF PF00808.18 KHN69697.1 - 0.053 13.5 0.1 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4635 PF15466.1 KHN69697.1 - 0.062 12.5 0.1 10 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) ORC2 PF04084.9 KHN69698.1 - 2.1e-16 59.6 6.7 4.9e-14 51.9 4.7 3.0 1 1 0 1 1 1 1 Origin recognition complex subunit 2 DUF4116 PF13475.1 KHN69698.1 - 0.0056 16.1 0.6 0.11 11.9 0.1 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4116) Sec7 PF01369.15 KHN69699.1 - 5.8e-32 110.9 2.1 2.1e-31 109.0 1.1 2.4 2 0 0 2 2 2 1 Sec7 domain RhoGEF PF00621.15 KHN69700.1 - 6.2e-05 22.9 0.1 0.00018 21.4 0.1 1.7 1 1 0 1 1 1 1 RhoGEF domain DUF711 PF05167.7 KHN69701.1 - 0.018 13.7 0.2 0.02 13.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) FF PF01846.14 KHN69701.1 - 0.022 14.7 0.4 0.28 11.1 0.1 2.0 2 0 0 2 2 2 0 FF domain SieB PF14163.1 KHN69701.1 - 0.059 12.9 0.4 0.099 12.2 0.0 1.5 2 0 0 2 2 2 0 Superinfection exclusion protein B CCDC-167 PF15188.1 KHN69701.1 - 0.069 13.0 1.1 0.084 12.8 0.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 ING PF12998.2 KHN69701.1 - 0.12 12.6 2.0 0.15 12.3 1.4 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding PC_rep PF01851.17 KHN69702.1 - 0.0099 16.0 1.3 0.042 14.1 0.2 2.5 2 0 0 2 2 2 1 Proteasome/cyclosome repeat XPA_C PF05181.7 KHN69703.1 - 1.9e-16 59.3 0.7 3.3e-16 58.6 0.5 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 KHN69703.1 - 0.008 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 XPA protein N-terminal UFD1 PF03152.9 KHN69704.1 - 1.6e-39 134.8 0.0 2.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Curto_V2 PF07325.6 KHN69705.1 - 0.78 9.4 6.1 0.17 11.5 0.1 2.7 3 0 0 3 3 3 0 Curtovirus V2 protein CK_II_beta PF01214.13 KHN69706.1 - 2.6e-49 167.2 0.2 9.9e-49 165.3 0.2 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DNA_pol_B_exo1 PF03104.14 KHN69707.1 - 1.4e-37 129.2 6.1 5.8e-37 127.2 1.0 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KHN69707.1 - 2.8e-20 72.5 12.7 3.9e-18 65.4 5.0 3.4 2 1 0 2 2 2 2 DNA polymerase family B DUF1744 PF08490.7 KHN69707.1 - 6.4e-11 41.4 0.2 1.3e-09 37.1 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1744) RNase_H_2 PF13482.1 KHN69707.1 - 1.9e-07 31.0 0.0 1.5e-06 28.1 0.0 2.7 1 0 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KHN69707.1 - 4.7e-07 29.5 1.5 3.1e-06 26.8 0.2 2.9 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB IBN_N PF03810.14 KHN69709.1 - 8.4e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain FH2 PF02181.18 KHN69710.1 - 2.9e-08 33.0 3.7 4.2e-08 32.4 2.5 1.3 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.4 KHN69710.1 - 1.9e-06 27.6 2.3 4.3e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein Acyltransferase PF01553.16 KHN69711.1 - 6.4e-20 70.9 0.0 9.7e-20 70.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Metallophos PF00149.23 KHN69712.1 - 7.3e-30 103.8 1.0 9.2e-30 103.5 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF59 PF01883.14 KHN69713.1 - 0.00079 19.3 0.2 0.013 15.4 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function DUF59 Ribosomal_L44 PF00935.14 KHN69714.1 - 1.9e-26 91.8 6.2 1.9e-26 91.8 4.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L44 CytoC_RC PF02276.13 KHN69714.1 - 0.14 11.2 1.4 0.17 10.9 0.9 1.2 1 1 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit DUF866 PF05907.8 KHN69714.1 - 0.25 10.7 2.4 0.81 9.1 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) Cytochrom_c3_2 PF14537.1 KHN69714.1 - 0.55 10.6 4.6 2.9 8.2 3.2 1.9 1 1 0 1 1 1 0 Cytochrome c3 UQ_con PF00179.21 KHN69715.1 - 4.7e-46 155.6 0.0 5.7e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KHN69715.1 - 1.5e-05 24.7 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KHN69715.1 - 0.04 13.8 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain SNF2_N PF00176.18 KHN69716.1 - 1.5e-68 230.7 1.4 1.5e-68 230.7 1.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KHN69716.1 - 4.2e-16 58.5 0.0 1.8e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69716.1 - 4.5e-11 42.9 0.0 1.5e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLIDE PF09111.5 KHN69716.1 - 3.6e-10 39.5 4.3 3.6e-10 39.5 3.0 3.1 3 1 0 3 3 3 1 SLIDE DEAD PF00270.24 KHN69716.1 - 3.1e-09 36.5 0.0 5.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KHN69716.1 - 5.1e-09 35.3 0.0 2.5e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HAND PF09110.6 KHN69716.1 - 8e-06 26.2 5.5 9.5e-06 25.9 1.6 2.7 2 1 1 3 3 3 1 HAND UCH PF00443.24 KHN69717.1 - 6.4e-44 150.0 5.6 9.8e-44 149.4 3.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KHN69717.1 - 7e-25 88.0 2.0 1.4e-24 87.0 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 7TMR-DISM_7TM PF07695.6 KHN69717.1 - 0.043 13.4 5.9 0.095 12.3 4.1 1.5 1 0 0 1 1 1 0 7TM diverse intracellular signalling Fusion_gly_K PF01621.12 KHN69718.1 - 0.0089 15.1 1.1 0.0097 14.9 0.8 1.1 1 0 0 1 1 1 1 Cell fusion glycoprotein K DUF1430 PF07242.6 KHN69718.1 - 0.022 14.8 7.5 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Choline_transpo PF04515.7 KHN69718.1 - 0.023 13.4 1.0 0.028 13.1 0.7 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Pex24p PF06398.6 KHN69718.1 - 0.029 13.1 0.1 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3112 PF11309.3 KHN69718.1 - 0.033 13.9 0.4 0.047 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Tmemb_9 PF05434.6 KHN69718.1 - 0.037 13.7 0.3 0.056 13.1 0.1 1.4 1 1 0 1 1 1 0 TMEM9 NB PF04159.8 KHN69718.1 - 0.072 12.8 0.2 0.072 12.8 0.1 2.2 1 1 1 2 2 2 0 NB glycoprotein Bacteriocin_IId PF09221.5 KHN69718.1 - 0.075 12.9 1.2 0.18 11.7 0.8 1.6 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like PRA1 PF03208.14 KHN69718.1 - 0.094 12.0 1.2 0.15 11.3 0.3 1.6 2 0 0 2 2 2 0 PRA1 family protein SPC12 PF06645.8 KHN69718.1 - 0.096 12.5 6.5 1.1 9.1 2.6 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Baculo_11_kDa PF06143.6 KHN69718.1 - 0.25 10.7 4.4 0.13 11.6 0.8 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family Orbi_NS3 PF01616.11 KHN69718.1 - 0.3 10.0 1.9 0.41 9.5 1.3 1.3 1 1 0 1 1 1 0 Orbivirus NS3 DUF2545 PF10810.3 KHN69718.1 - 0.33 11.3 5.4 4.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) DUF1077 PF06417.7 KHN69718.1 - 0.68 9.2 8.6 1.1 8.6 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1077) DUF3784 PF12650.2 KHN69718.1 - 2 8.4 10.2 1.8 8.5 5.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Peroxin-3 PF04882.7 KHN69720.1 - 0.0034 16.1 1.7 0.0051 15.5 1.2 1.3 1 0 0 1 1 1 1 Peroxin-3 Adaptin_binding PF10199.4 KHN69720.1 - 0.016 15.4 1.7 0.016 15.4 1.2 2.2 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 tRNA-synt_His PF13393.1 KHN69722.1 - 0.036 13.1 1.1 0.094 11.7 0.7 1.6 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF912 PF06024.7 KHN69722.1 - 0.12 12.4 9.2 1.5 8.9 2.9 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rad10 PF03834.9 KHN69724.1 - 1.6e-20 72.5 0.1 3.9e-20 71.3 0.1 1.6 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KHN69724.1 - 3.8e-06 26.9 0.0 6.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KHN69724.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.18 KHN69724.1 - 0.033 13.8 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3701 PF12482.3 KHN69724.1 - 0.089 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage integrase protein RNA_pol_A_CTD PF03118.10 KHN69724.1 - 0.096 12.1 0.0 0.24 10.8 0.0 1.7 1 1 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain ECR1_N PF14382.1 KHN69725.1 - 3.6e-08 32.5 0.1 6.8e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KHN69725.1 - 3.7e-05 23.6 1.3 0.0014 18.5 0.5 2.9 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 Beta-Casp PF10996.3 KHN69726.1 - 1.8e-26 92.5 0.0 7.4e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KHN69726.1 - 7.6e-16 58.3 0.4 2e-15 56.9 0.3 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KHN69726.1 - 6.9e-13 48.1 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KHN69726.1 - 9.7e-10 38.3 0.6 1.9e-08 34.0 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KHN69726.1 - 0.0002 21.0 0.0 0.00049 19.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF167 PF02594.11 KHN69726.1 - 0.023 14.6 0.2 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YggU family COG1872 MS_channel PF00924.13 KHN69727.1 - 4.8e-13 48.9 0.4 9.5e-13 47.9 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KHN69727.1 - 0.0049 16.0 0.2 0.0049 16.0 0.1 2.4 3 0 0 3 3 3 1 EF hand PIG-F PF06699.6 KHN69727.1 - 0.012 15.5 0.2 0.012 15.5 0.2 2.5 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F EF-hand_6 PF13405.1 KHN69727.1 - 0.027 14.3 0.2 0.17 11.8 0.1 2.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 KHN69727.1 - 0.098 12.2 0.5 0.49 10.0 0.3 2.2 1 0 0 1 1 1 0 EF-hand domain pair DUF761 PF05553.6 KHN69727.1 - 0.11 11.9 0.6 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Cotton fibre expressed protein Exo_endo_phos PF03372.18 KHN69728.1 - 7.7e-16 58.7 0.0 9.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KHN69728.1 - 0.0011 18.6 0.6 0.0028 17.2 0.4 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase HECT PF00632.20 KHN69729.1 - 7.2e-85 284.9 0.5 7.2e-85 284.9 0.3 2.2 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) VCBS PF13517.1 KHN69731.1 - 0.022 15.1 4.5 0.65 10.3 0.1 4.2 4 1 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KHN69731.1 - 0.032 13.6 0.1 3.1 7.2 0.0 2.6 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region DUF2303 PF10065.4 KHN69731.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) MFS_1 PF07690.11 KHN69732.1 - 4.7e-20 71.6 23.8 4.7e-20 71.6 16.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily SHR3_chaperone PF08229.6 KHN69732.1 - 0.31 9.9 2.7 4.5 6.1 0.0 3.0 3 0 0 3 3 3 0 ER membrane protein SH3 AAA PF00004.24 KHN69733.1 - 9.4e-42 142.3 0.1 2.7e-41 140.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN69733.1 - 8.6e-07 28.7 0.5 4.1e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KHN69733.1 - 3.8e-06 26.9 0.0 1.6e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KHN69733.1 - 3.8e-06 27.0 0.0 0.0036 17.3 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 KHN69733.1 - 9.8e-06 24.7 0.0 2.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KHN69733.1 - 0.00088 19.4 0.7 0.07 13.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 KHN69733.1 - 0.0022 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN69733.1 - 0.0026 18.5 0.1 0.0083 16.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 KHN69733.1 - 0.0095 14.8 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KHN69733.1 - 0.0097 15.0 0.1 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KHN69733.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KHN69733.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 KHN69733.1 - 0.017 14.3 0.0 0.087 12.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 KHN69733.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KHN69733.1 - 0.02 14.3 0.8 0.96 8.8 0.1 2.5 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 KHN69733.1 - 0.024 14.7 0.0 0.07 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 KHN69733.1 - 0.039 13.0 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 KHN69733.1 - 0.04 13.5 0.2 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KHN69733.1 - 0.055 12.5 0.3 0.74 8.8 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 KHN69733.1 - 0.062 12.7 0.1 0.4 10.1 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Syntaxin-6_N PF09177.6 KHN69733.1 - 0.14 12.5 0.9 1.7 9.0 0.0 2.5 3 0 0 3 3 2 0 Syntaxin 6, N-terminal Bromodomain PF00439.20 KHN69734.1 - 1.7e-23 82.3 0.7 1.7e-23 82.3 0.5 2.3 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 KHN69734.1 - 9.7e-07 28.8 0.2 3.3e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KHN69734.1 - 0.0025 17.8 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KHN69734.1 - 0.11 12.6 0.0 0.82 9.8 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain PAP2 PF01569.16 KHN69735.1 - 5.4e-22 77.8 4.1 5.4e-22 77.8 2.8 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 KHN69735.1 - 0.00064 19.1 2.6 0.04 13.3 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) PAP2_3 PF14378.1 KHN69735.1 - 0.0019 17.7 6.5 0.0048 16.4 4.5 1.7 1 1 0 1 1 1 1 PAP2 superfamily EamA PF00892.15 KHN69735.1 - 0.0042 17.1 4.3 0.019 14.9 0.3 2.5 2 0 0 2 2 2 1 EamA-like transporter family GWT1 PF06423.7 KHN69735.1 - 0.13 12.3 5.2 0.27 11.3 0.3 2.2 2 0 0 2 2 2 0 GWT1 MARVEL PF01284.18 KHN69735.1 - 0.31 10.8 8.8 1.7 8.4 0.6 2.3 2 0 0 2 2 2 0 Membrane-associating domain DUF4181 PF13789.1 KHN69735.1 - 0.5 10.2 4.3 0.4 10.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) PAP2_C PF14360.1 KHN69735.1 - 0.93 9.8 8.0 0.2 11.9 0.8 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal TRP PF06011.7 KHN69735.1 - 1.4 7.3 11.9 2.4 6.6 3.4 2.3 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Proteasome PF00227.21 KHN69736.1 - 6.6e-39 133.1 0.8 7.6e-39 132.9 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit tRNA-synt_1c PF00749.16 KHN69737.1 - 2.8e-90 302.1 0.4 7.9e-90 300.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KHN69737.1 - 2.6e-33 115.1 0.0 5.8e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 KHN69737.1 - 0.00035 20.1 0.7 0.00066 19.2 0.5 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 IFN-gamma PF00714.12 KHN69738.1 - 0.13 12.1 0.7 0.14 12.0 0.5 1.1 1 0 0 1 1 1 0 Interferon gamma Latarcin PF10279.4 KHN69738.1 - 0.22 11.7 1.2 0.24 11.6 0.8 1.1 1 0 0 1 1 1 0 Latarcin precursor Peptidase_M16 PF00675.15 KHN69739.1 - 4.6e-33 114.0 0.0 1.3e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KHN69739.1 - 4.9e-14 52.4 0.1 3.3e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain HSBP1 PF06825.7 KHN69740.1 - 0.034 13.7 0.5 0.073 12.6 0.4 1.8 1 1 0 1 1 1 0 Heat shock factor binding protein 1 Homeobox_KN PF05920.6 KHN69741.1 - 1.6e-17 62.9 0.1 2.8e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KHN69741.1 - 3.9e-05 23.1 0.0 7.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain Saccharop_dh PF03435.13 KHN69742.1 - 9.6e-21 74.1 0.0 3.9e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase zf-CCCH PF00642.19 KHN69744.1 - 6.7e-06 25.6 10.9 1.1e-05 24.9 0.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KHN69744.1 - 0.0029 17.5 2.4 0.0029 17.5 1.7 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type zf-C3H1 PF10650.4 KHN69744.1 - 7.4 6.1 10.7 0.48 9.9 0.7 2.9 2 1 0 2 2 2 0 Putative zinc-finger domain Ribosomal_L24e PF01246.15 KHN69745.1 - 2.3e-24 85.0 3.7 4.2e-24 84.2 2.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 KHN69745.1 - 0.00031 20.3 5.7 0.00031 20.3 4.0 1.8 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif ABC_tran PF00005.22 KHN69746.1 - 6.3e-24 84.8 0.3 1.8e-23 83.3 0.1 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KHN69746.1 - 6.2e-06 25.5 0.1 1.1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KHN69746.1 - 8.4e-06 25.9 3.2 0.034 14.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.1 KHN69746.1 - 0.00011 21.3 1.5 0.2 10.6 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KHN69746.1 - 0.0027 17.2 0.4 0.0056 16.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KHN69746.1 - 0.0064 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN69746.1 - 0.0065 17.2 0.0 0.018 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KHN69746.1 - 0.0086 15.7 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KHN69746.1 - 0.017 14.3 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KHN69746.1 - 0.02 14.2 0.1 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KHN69746.1 - 0.022 14.8 1.6 0.081 13.0 1.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KHN69746.1 - 0.04 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KHN69746.1 - 0.11 11.8 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 KHN69746.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KHN69746.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DDT PF02791.12 KHN69747.1 - 0.03 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 DDT domain UQ_con PF00179.21 KHN69748.1 - 2e-22 79.1 0.0 2.4e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S24e PF01282.14 KHN69750.1 - 4.6e-18 64.7 0.9 5.8e-18 64.4 0.4 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e DUF3991 PF13154.1 KHN69750.1 - 0.015 15.4 1.0 0.083 13.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3991) NodZ PF05830.6 KHN69750.1 - 0.029 12.9 0.2 0.034 12.7 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Molybdopterin PF00384.17 KHN69750.1 - 0.038 12.7 0.6 0.042 12.5 0.4 1.0 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Ribosomal_S30 PF04758.9 KHN69751.1 - 1.3e-18 66.4 2.0 1.6e-18 66.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 LSM PF01423.17 KHN69752.1 - 1.9e-14 52.9 0.5 3.1e-14 52.2 0.3 1.4 1 0 0 1 1 1 1 LSM domain CTP_transf_2 PF01467.21 KHN69753.1 - 1.2e-16 61.1 0.0 2.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Mnd1 PF03962.10 KHN69754.1 - 3.7e-48 163.7 7.5 4.2e-48 163.5 5.2 1.0 1 0 0 1 1 1 1 Mnd1 family APG6 PF04111.7 KHN69754.1 - 0.0043 16.1 5.2 0.0063 15.5 3.6 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 TrmB PF01978.14 KHN69754.1 - 0.0074 15.9 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB GAS PF13851.1 KHN69754.1 - 0.0097 15.1 8.7 0.023 13.8 6.0 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Penicillinase_R PF03965.11 KHN69754.1 - 0.011 15.8 0.2 0.098 12.7 0.1 2.1 2 1 0 2 2 2 0 Penicillinase repressor HAUS5 PF14817.1 KHN69754.1 - 0.03 12.8 1.4 0.041 12.4 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Sterile PF03015.14 KHN69754.1 - 0.032 14.4 0.2 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein Takusan PF04822.8 KHN69754.1 - 0.067 12.9 7.3 0.12 12.1 4.7 1.8 1 1 0 1 1 1 0 Takusan Atg14 PF10186.4 KHN69754.1 - 0.07 12.0 1.9 0.095 11.6 1.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF793 PF05633.6 KHN69754.1 - 0.14 10.9 4.0 0.18 10.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) TBPIP PF07106.8 KHN69754.1 - 0.27 10.7 11.4 0.37 10.3 7.9 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2408 PF10303.4 KHN69754.1 - 0.42 10.7 10.2 0.46 10.6 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 KHN69754.1 - 5.9 5.1 11.0 1.9 6.7 5.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Pico_P2B PF01552.12 KHN69755.1 - 0.048 13.8 0.6 0.15 12.1 0.4 1.9 1 0 0 1 1 1 0 Picornavirus 2B protein H-kinase_dim PF02895.9 KHN69755.1 - 0.097 13.0 0.2 0.32 11.3 0.0 1.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain TrfA PF07042.6 KHN69756.1 - 0.025 13.4 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 TrfA protein V-ATPase_H_N PF03224.9 KHN69756.1 - 0.048 12.7 0.3 0.074 12.1 0.2 1.2 1 0 0 1 1 1 0 V-ATPase subunit H zf-C2H2_3 PF13878.1 KHN69756.1 - 0.066 12.7 2.6 0.4 10.2 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PDGF_N PF04692.8 KHN69756.1 - 0.45 11.0 3.1 1.4 9.4 2.2 1.8 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region HJURP_mid PF12346.3 KHN69758.1 - 0.053 13.6 1.8 3.9 7.6 0.1 3.1 2 1 1 3 3 3 0 Holliday junction recognition protein-associated repeat RAP1 PF07218.6 KHN69759.1 - 0.44 8.5 8.3 0.64 8.0 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DEAD PF00270.24 KHN69760.1 - 2.8e-44 150.5 0.0 5.6e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69760.1 - 9.6e-21 73.4 0.0 2.1e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69760.1 - 0.00071 19.4 0.0 0.0018 18.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KHN69760.1 - 0.0074 15.6 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_19 PF13245.1 KHN69760.1 - 0.1 12.3 0.0 0.76 9.5 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain Enolase_C PF00113.17 KHN69761.1 - 6.2e-83 278.1 0.0 9.1e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KHN69761.1 - 2.3e-37 127.8 0.0 3.4e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 KHN69761.1 - 0.0033 16.3 0.0 0.0065 15.4 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 KHN69761.1 - 0.0063 16.4 0.1 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KHN69761.1 - 0.18 12.3 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Rpr2 PF04032.11 KHN69762.1 - 8.9e-18 63.9 4.7 1e-17 63.7 3.2 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Extensin-like_C PF06904.7 KHN69762.1 - 0.071 12.8 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Extensin-like protein C-terminus Dynamin_M PF01031.15 KHN69763.1 - 4.2e-80 268.6 0.0 4.2e-80 268.6 0.0 2.1 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.18 KHN69763.1 - 2.4e-49 167.3 0.2 5.2e-49 166.2 0.2 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KHN69763.1 - 1.5e-23 82.4 4.0 5.8e-23 80.5 2.8 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KHN69763.1 - 3.9e-05 23.5 0.2 0.00012 22.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KHN69763.1 - 0.024 15.1 0.0 0.086 13.3 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 KHN69763.1 - 0.074 13.0 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DcpS_C PF11969.3 KHN69764.1 - 7.5e-18 64.8 3.7 1.9e-17 63.5 0.1 2.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KHN69764.1 - 7.1e-07 29.5 1.4 2e-06 28.1 0.9 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal ubiquitin PF00240.18 KHN69765.1 - 4.5e-11 41.9 0.1 8.6e-11 41.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KHN69765.1 - 0.00039 20.1 0.1 0.0047 16.7 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 KHN69765.1 - 0.0092 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 KHN69765.1 - 0.02 14.4 0.1 4.9 6.7 0.0 3.0 2 0 0 2 2 2 0 CUE domain Ubiquitin_2 PF14560.1 KHN69765.1 - 0.029 14.5 3.9 0.06 13.6 0.1 2.9 2 1 1 3 3 3 0 Ubiquitin-like domain RasGAP_C PF03836.10 KHN69766.1 - 1.3e-25 89.7 0.3 1.3e-25 89.7 0.2 2.0 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 KHN69766.1 - 4e-09 36.4 2.8 1e-06 28.5 0.4 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 KHN69766.1 - 7.5e-07 29.1 0.0 2.7e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain Spc97_Spc98 PF04130.8 KHN69767.1 - 2.7e-33 115.1 6.4 1e-23 83.4 1.2 2.3 2 0 0 2 2 2 2 Spc97 / Spc98 family DUF4264 PF14084.1 KHN69767.1 - 0.022 14.1 0.0 0.48 9.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Pro_isomerase PF00160.16 KHN69768.1 - 1.8e-39 135.4 1.5 2.4e-39 135.0 1.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Nepo_coat_C PF03688.9 KHN69768.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Peptidase_M17 PF00883.16 KHN69769.1 - 2.7e-112 374.6 0.0 3.9e-112 374.1 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KHN69769.1 - 9.6e-11 41.5 0.3 1.7e-10 40.7 0.2 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain tRNA-synt_2b PF00587.20 KHN69771.1 - 1.3e-56 190.9 0.2 2.1e-56 190.1 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KHN69771.1 - 4.7e-14 52.0 0.0 1.6e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain DUF4006 PF13179.1 KHN69772.1 - 0.051 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) HAD_2 PF13419.1 KHN69773.1 - 8.3e-25 88.0 0.0 1.1e-24 87.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TB2_DP1_HVA22 PF03134.14 KHN69774.1 - 8.2e-12 44.7 4.4 1.2e-11 44.2 3.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ABC_tran PF00005.22 KHN69775.1 - 1e-39 135.9 4.4 2.9e-21 76.2 0.1 3.7 4 0 0 4 4 3 3 ABC transporter ABC_tran_2 PF12848.2 KHN69775.1 - 6.2e-23 80.4 0.3 1.4e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KHN69775.1 - 2.7e-19 70.2 7.2 0.00077 19.5 0.0 4.8 3 2 1 5 5 4 4 AAA domain SMC_N PF02463.14 KHN69775.1 - 1.2e-09 37.7 5.9 0.0024 17.1 0.0 4.5 3 2 2 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KHN69775.1 - 1.5e-07 31.6 0.3 0.0054 16.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KHN69775.1 - 5.3e-07 28.9 0.2 0.003 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KHN69775.1 - 1.6e-06 27.5 0.6 0.024 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KHN69775.1 - 1.9e-06 28.7 2.9 0.061 14.1 0.3 3.4 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 KHN69775.1 - 6.7e-06 26.6 0.4 0.065 13.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 KHN69775.1 - 6.7e-06 25.8 0.2 0.047 13.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain ABC_ATPase PF09818.4 KHN69775.1 - 1.9e-05 23.4 0.1 0.012 14.2 0.0 2.5 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KHN69775.1 - 2.3e-05 24.4 0.0 0.054 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 KHN69775.1 - 4.2e-05 23.2 0.6 0.024 14.3 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KHN69775.1 - 5.3e-05 23.5 4.9 0.076 13.3 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 KHN69775.1 - 6.9e-05 22.3 0.1 0.049 13.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 KHN69775.1 - 0.00011 22.5 11.1 0.16 12.2 0.2 3.1 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KHN69775.1 - 0.00011 22.2 0.0 0.047 13.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 KHN69775.1 - 0.00012 22.3 0.0 0.066 13.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 KHN69775.1 - 0.00028 20.0 21.4 0.04 12.9 0.1 5.2 4 2 1 6 6 6 2 AAA ATPase domain SbcCD_C PF13558.1 KHN69775.1 - 0.00031 20.5 6.8 0.0038 17.1 0.3 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KHN69775.1 - 0.0008 18.9 0.1 0.029 13.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 KHN69775.1 - 0.00086 18.7 0.3 1.4 8.3 0.0 2.6 3 0 0 3 3 2 2 SRP54-type protein, GTPase domain AAA_10 PF12846.2 KHN69775.1 - 0.00098 18.6 0.6 1.1 8.6 0.0 3.1 3 1 0 3 3 3 1 AAA-like domain AAA_28 PF13521.1 KHN69775.1 - 0.001 19.0 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KHN69775.1 - 0.0015 18.2 4.2 0.18 11.4 0.1 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 KHN69775.1 - 0.002 17.7 0.1 1 8.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KHN69775.1 - 0.0021 17.9 1.8 0.98 9.4 0.4 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Bac_DnaA PF00308.13 KHN69775.1 - 0.0022 17.6 1.8 0.0079 15.8 0.0 2.5 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_33 PF13671.1 KHN69775.1 - 0.004 17.0 0.0 0.84 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KHN69775.1 - 0.0044 15.9 0.5 0.036 12.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Abhydrolase_7 PF12715.2 KHN69775.1 - 0.005 15.8 0.0 0.0082 15.1 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase family Dynamin_N PF00350.18 KHN69775.1 - 0.0087 15.8 2.3 0.33 10.7 0.2 3.0 3 0 0 3 3 3 1 Dynamin family PduV-EutP PF10662.4 KHN69775.1 - 0.0089 15.5 0.1 0.93 8.9 0.0 2.7 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KHN69775.1 - 0.014 15.0 4.7 3.1 7.4 0.0 3.5 4 0 0 4 4 4 0 NTPase FtsK_SpoIIIE PF01580.13 KHN69775.1 - 0.027 13.9 0.8 0.2 11.0 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 KHN69775.1 - 0.03 13.7 0.9 3.3 7.1 0.1 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 KHN69775.1 - 0.037 13.6 3.2 5 6.7 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 KHN69775.1 - 0.049 12.5 0.7 0.32 9.8 0.0 2.3 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 KHN69775.1 - 0.063 12.8 2.6 3.7 7.0 0.2 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 KHN69775.1 - 0.065 12.9 0.8 9.5 5.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 KHN69775.1 - 0.49 9.6 7.1 0.42 9.8 0.0 3.0 3 1 0 3 3 3 0 Poxvirus A32 protein Septin PF00735.13 KHN69775.1 - 0.54 9.2 6.3 5.4 5.9 0.0 3.6 4 0 0 4 4 4 0 Septin DNA_primase_lrg PF04104.9 KHN69776.1 - 6.2e-52 176.4 4.1 8.3e-52 176.0 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit T2SE PF00437.15 KHN69776.1 - 0.041 12.7 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SNARE PF05739.14 KHN69777.1 - 7.2e-08 32.0 0.3 4e-07 29.6 0.0 2.3 2 1 1 3 3 3 1 SNARE domain Monooxygenase_B PF04744.7 KHN69777.1 - 0.068 11.8 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 Monooxygenase subunit B protein Syntaxin PF00804.20 KHN69777.1 - 0.073 13.2 6.1 0.25 11.5 3.3 2.5 1 1 0 2 2 2 0 Syntaxin DASH_Dad4 PF08650.5 KHN69777.1 - 0.25 11.2 1.8 0.56 10.1 0.6 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 Syntaxin-6_N PF09177.6 KHN69777.1 - 0.31 11.4 2.3 3.7 8.0 0.0 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 KHN69777.1 - 0.33 10.5 3.7 0.88 9.1 1.2 2.1 2 0 0 2 2 2 0 IncA protein DUF2746 PF10874.3 KHN69777.1 - 4.7 7.4 7.5 27 5.0 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2746) G10 PF01125.12 KHN69778.1 - 7.4e-47 158.5 2.8 8.1e-47 158.4 1.9 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 KHN69778.1 - 1.6 8.2 11.2 1.1 8.8 4.5 2.3 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit G_glu_transpept PF01019.16 KHN69779.1 - 4.3e-141 470.8 0.0 4.9e-141 470.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DEAD PF00270.24 KHN69781.1 - 6.8e-31 107.0 0.0 4.7e-30 104.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69781.1 - 6.7e-19 67.5 0.2 1.4e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69781.1 - 3.2e-05 23.8 0.1 0.00016 21.5 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KHN69781.1 - 0.0051 15.6 0.0 0.0088 14.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Metallophos PF00149.23 KHN69782.1 - 1.7e-22 79.7 0.4 4e-22 78.5 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KHN69782.1 - 3.3e-14 53.0 0.0 5.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mre11_DNA_bind PF04152.9 KHN69782.1 - 1.1e-06 28.6 1.3 1.4e-05 25.0 0.9 2.6 1 1 0 1 1 1 1 Mre11 DNA-binding presumed domain DUF504 PF04457.7 KHN69783.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) MalM PF07148.7 KHN69783.1 - 0.035 13.5 0.3 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Maltose operon periplasmic protein precursor (MalM) Nnf1 PF03980.9 KHN69783.1 - 0.094 12.7 0.6 6.9 6.7 0.1 2.4 2 1 0 2 2 2 0 Nnf1 Pox_I3 PF04661.7 KHN69783.1 - 0.12 11.1 3.8 0.28 9.9 0.1 2.1 2 0 0 2 2 2 0 Poxvirus I3 ssDNA-binding protein DUF2404 PF10296.4 KHN69784.1 - 1.6e-06 28.1 0.0 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) LSM PF01423.17 KHN69785.1 - 5.2e-12 45.1 1.3 1.1e-11 44.0 0.4 1.8 1 1 1 2 2 2 1 LSM domain Ribosomal_S4 PF00163.14 KHN69786.1 - 1.8e-08 34.6 1.6 2.9e-08 33.9 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KHN69786.1 - 1.2e-07 31.0 0.0 2.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain Exo5 PF09810.4 KHN69786.1 - 0.032 13.4 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease zf-DBF PF07535.7 KHN69787.1 - 1.7e-16 59.6 1.3 1.7e-16 59.6 0.9 1.7 2 0 0 2 2 2 1 DBF zinc finger DUF4451 PF14616.1 KHN69787.1 - 0.0017 18.1 0.5 0.0022 17.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Dfp1_Him1_M PF08630.5 KHN69787.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Dfp1/Him1, central region Proteasome PF00227.21 KHN69788.1 - 6.6e-32 110.3 0.0 8e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN69788.1 - 0.04 13.2 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature PUA PF01472.15 KHN69789.1 - 7.4e-10 38.4 1.6 1.4e-09 37.5 1.1 1.5 1 0 0 1 1 1 1 PUA domain NTP_transferase PF00483.18 KHN69790.1 - 7.1e-07 28.7 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KHN69790.1 - 0.00047 20.2 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 KHN69790.1 - 0.0017 17.7 4.4 0.9 9.1 0.1 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 KHN69790.1 - 0.0019 16.8 0.3 0.0033 16.0 0.2 1.4 1 0 0 1 1 1 1 L-fucokinase Bactofilin PF04519.8 KHN69790.1 - 0.16 11.9 3.6 1.5 8.9 0.8 2.2 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Hexapep_2 PF14602.1 KHN69790.1 - 0.67 9.5 6.2 2 8.0 1.2 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Peptidase_M48 PF01435.13 KHN69791.1 - 3.9e-09 36.4 0.0 6.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Glutaredoxin PF00462.19 KHN69792.1 - 8.6e-15 54.4 0.0 3.2e-12 46.2 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Peptidase_M48 PF01435.13 KHN69793.1 - 2.8e-08 33.6 0.0 6.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M48 tRNA_anti-like PF12869.2 KHN69793.1 - 0.03 13.8 0.0 3.9 6.9 0.0 2.5 1 1 1 2 2 2 0 tRNA_anti-like DUF4149 PF13664.1 KHN69793.1 - 0.63 10.1 11.7 0.16 12.0 4.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Proteasome PF00227.21 KHN69794.1 - 2.6e-47 160.5 0.1 3.1e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN69794.1 - 9.1e-10 37.6 0.0 1.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TPR_7 PF13176.1 KHN69795.1 - 0.0075 15.9 0.2 0.38 10.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Arrestin_N PF00339.24 KHN69796.1 - 1.1e-08 34.9 0.0 4.5e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KHN69796.1 - 1.9e-06 28.0 0.1 0.0024 18.0 0.1 2.5 1 1 1 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PTPLA PF04387.9 KHN69797.1 - 3.3e-22 78.6 16.8 3.1e-21 75.4 11.6 2.0 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA RRM_1 PF00076.17 KHN69798.1 - 1.4e-13 50.2 2.0 7e-10 38.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69798.1 - 5.8e-13 48.6 0.2 1.4e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69798.1 - 0.00025 20.8 0.2 1.2 9.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KHN69798.1 - 0.017 14.9 0.2 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif MBOAT PF03062.14 KHN69800.1 - 5.3e-15 55.3 28.5 8.4e-15 54.7 19.6 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sas10 PF09368.5 KHN69802.1 - 0.0014 18.8 8.3 0.0025 17.9 5.7 1.4 1 0 0 1 1 1 1 Sas10 C-terminal domain DUF4119 PF13494.1 KHN69802.1 - 0.035 14.0 1.4 0.061 13.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Sas10_Utp3 PF04000.10 KHN69802.1 - 0.039 14.1 1.5 0.053 13.7 0.2 1.8 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Sporozoite_P67 PF05642.6 KHN69802.1 - 0.071 10.9 0.4 0.085 10.7 0.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4167 PF13763.1 KHN69802.1 - 0.26 11.3 2.8 0.56 10.2 2.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) Ribosomal_L7Ae PF01248.21 KHN69803.1 - 2.2e-12 46.3 0.0 2.6e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ubiquitin PF00240.18 KHN69804.1 - 0.0053 16.1 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KHN69804.1 - 0.0068 16.0 0.2 0.0084 15.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BING4CT PF08149.6 KHN69805.1 - 2.2e-28 97.5 0.0 9.5e-28 95.5 0.0 2.1 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KHN69805.1 - 1.1e-06 28.2 0.1 1e-05 25.2 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Pkinase PF00069.20 KHN69806.1 - 8e-60 202.1 1.2 9.5e-60 201.9 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN69806.1 - 1.4e-29 102.9 0.2 1.9e-29 102.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KHN69806.1 - 8.8e-08 32.1 0.0 0.00042 20.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KHN69806.1 - 0.0015 18.1 4.6 0.0036 16.8 0.8 2.5 2 1 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 KHN69806.1 - 0.042 13.1 0.6 0.22 10.8 0.0 2.1 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 KHN69806.1 - 0.069 12.0 0.0 0.099 11.5 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Borrelia_lipo_2 PF06238.6 KHN69806.1 - 4.1 7.5 7.1 1.7 8.7 0.4 2.3 1 1 1 2 2 2 0 Borrelia burgdorferi BBR25 lipoprotein 4HBT_3 PF13622.1 KHN69807.1 - 5.7e-13 49.2 0.0 1.7e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KHN69807.1 - 4.2e-10 39.3 0.0 2e-06 27.4 0.0 2.7 2 1 1 3 3 3 2 Acyl-CoA thioesterase RFC1 PF08519.7 KHN69808.1 - 9.2e-33 113.1 0.1 1.8e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain AAA PF00004.24 KHN69808.1 - 5.9e-14 52.3 0.1 1.4e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 KHN69808.1 - 5.8e-12 45.5 0.0 1.9e-11 43.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 KHN69808.1 - 1.8e-10 40.1 0.0 1.3e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KHN69808.1 - 3.3e-08 32.8 0.0 5.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KHN69808.1 - 1.3e-06 29.1 1.3 1.1e-05 26.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 KHN69808.1 - 1.1e-05 25.2 0.1 0.0022 17.7 0.0 3.2 2 1 1 3 3 3 1 NTPase AAA_22 PF13401.1 KHN69808.1 - 1.6e-05 25.0 0.0 0.0003 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KHN69808.1 - 2.3e-05 24.3 1.2 3.1e-05 23.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 KHN69808.1 - 6.4e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 KHN69808.1 - 0.0001 21.5 0.0 0.00023 20.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 KHN69808.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KHN69808.1 - 0.00049 20.4 0.7 0.0077 16.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KHN69808.1 - 0.00057 19.6 0.0 0.0029 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KHN69808.1 - 0.00086 18.1 0.1 0.0021 16.8 0.0 1.7 1 1 0 1 1 1 1 TIP49 C-terminus PTCB-BRCT PF12738.2 KHN69808.1 - 0.00093 19.0 0.0 0.0032 17.2 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain AAA_16 PF13191.1 KHN69808.1 - 0.0043 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KHN69808.1 - 0.005 16.5 0.3 0.037 13.6 0.1 2.2 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 KHN69808.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KHN69808.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KHN69808.1 - 0.014 14.3 0.1 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_2 PF07724.9 KHN69808.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NB-ARC PF00931.17 KHN69808.1 - 0.034 13.0 0.0 0.063 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DEAD PF00270.24 KHN69808.1 - 0.037 13.5 0.1 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.6 KHN69808.1 - 0.046 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KHN69808.1 - 0.063 12.7 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SE PF00437.15 KHN69808.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_pol3_delta2 PF13177.1 KHN69808.1 - 0.082 12.5 0.6 0.83 9.2 0.0 2.6 2 1 0 2 2 2 0 DNA polymerase III, delta subunit AAA_33 PF13671.1 KHN69808.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KHN69808.1 - 0.11 12.7 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.13 KHN69808.1 - 0.13 11.7 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PCI PF01399.22 KHN69810.1 - 3.3e-14 53.0 0.8 8.4e-14 51.7 0.1 2.0 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 KHN69810.1 - 0.00022 20.9 0.9 0.001 18.8 0.1 2.4 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 ComX PF05952.7 KHN69810.1 - 0.094 12.2 0.1 0.63 9.5 0.0 2.3 2 0 0 2 2 2 0 Bacillus competence pheromone ComX RII_binding_1 PF10522.4 KHN69810.1 - 0.12 12.6 0.3 0.66 10.3 0.0 2.5 2 0 0 2 2 2 0 RII binding domain DUF1980 PF09323.5 KHN69811.1 - 0.00052 19.8 0.2 0.0032 17.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1980) PIG-Y PF15159.1 KHN69811.1 - 0.6 10.3 3.5 1.3 9.2 1.0 2.5 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GWT1 PF06423.7 KHN69812.1 - 0.00027 21.0 5.6 0.00027 21.0 3.9 3.8 3 1 0 3 3 3 1 GWT1 OSTMP1 PF09777.4 KHN69812.1 - 0.11 11.6 1.0 0.85 8.7 0.0 2.3 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor GTP_EFTU PF00009.22 KHN69813.1 - 7.4e-32 110.3 0.0 3.4e-31 108.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KHN69813.1 - 1.5e-12 47.3 2.1 4.6e-12 45.7 1.4 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KHN69813.1 - 3e-10 40.0 6.7 7.5e-07 29.1 0.0 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KHN69813.1 - 1.3e-06 27.9 0.9 4.1e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KHN69813.1 - 1.7e-06 27.9 0.0 5.1e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KHN69813.1 - 0.00088 19.7 0.0 0.0026 18.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KHN69813.1 - 0.0067 15.6 0.0 0.022 13.9 0.0 2.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KHN69813.1 - 0.0083 15.6 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MCE PF02470.15 KHN69813.1 - 0.01 15.8 0.5 5.9 6.9 0.0 3.3 3 0 0 3 3 3 0 mce related protein Ras PF00071.17 KHN69813.1 - 0.016 14.6 0.0 0.063 12.6 0.0 2.0 2 0 0 2 2 2 0 Ras family zf-C3HC4_3 PF13920.1 KHN69816.1 - 1.4e-07 31.0 12.5 1.4e-07 31.0 8.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KHN69816.1 - 1.2e-06 28.3 15.1 5.8e-06 26.2 10.5 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KHN69816.1 - 7.2e-05 22.3 15.8 7.2e-05 22.3 10.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KHN69816.1 - 0.00036 20.2 11.9 0.00036 20.2 8.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 KHN69816.1 - 0.0026 17.5 5.3 0.0068 16.1 3.6 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 KHN69816.1 - 0.0038 16.9 14.3 0.016 14.9 9.9 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KHN69816.1 - 0.4 10.5 17.1 0.05 13.4 8.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING IKKbetaNEMObind PF12179.3 KHN69816.1 - 0.61 9.9 4.0 0.72 9.7 0.8 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain zf-RING_UBOX PF13445.1 KHN69816.1 - 2.2 8.0 10.9 3.4 7.4 6.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 KHN69816.1 - 2.4 7.8 12.4 6.8 6.3 8.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Formyl_trans_C PF02911.13 KHN69817.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Baculo_VP91_N PF08475.5 KHN69818.1 - 0.1 11.9 2.0 3.5 6.9 0.3 2.3 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal DUF3753 PF12575.3 KHN69818.1 - 0.5 10.2 3.8 0.45 10.3 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) SecY PF00344.15 KHN69819.1 - 6.1e-74 248.9 21.9 7.7e-74 248.6 15.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KHN69819.1 - 5.4e-18 64.2 0.1 1.8e-17 62.5 0.1 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Peptidase_M22 PF00814.20 KHN69820.1 - 6.5e-82 275.0 0.0 7.7e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family HA2 PF04408.18 KHN69821.1 - 5.2e-17 61.7 0.0 1.4e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KHN69821.1 - 3.4e-12 46.0 0.0 1.1e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KHN69821.1 - 1.2e-10 41.2 0.1 2.4e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KHN69821.1 - 3.4e-07 29.9 0.1 8.7e-07 28.5 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KHN69821.1 - 7e-06 26.2 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KHN69821.1 - 0.00036 19.7 0.6 0.0075 15.4 0.0 2.8 3 0 0 3 3 3 1 KaiC NB-ARC PF00931.17 KHN69821.1 - 0.00072 18.4 0.2 0.014 14.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain T2SE PF00437.15 KHN69821.1 - 0.0047 15.8 0.1 0.011 14.6 0.0 1.5 1 1 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KHN69821.1 - 0.0066 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KHN69821.1 - 0.0082 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 KHN69821.1 - 0.0089 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain IstB_IS21 PF01695.12 KHN69821.1 - 0.026 13.9 0.4 5 6.5 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein ABC_tran PF00005.22 KHN69821.1 - 0.04 14.2 0.1 0.18 12.0 0.1 2.0 1 1 1 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 KHN69821.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KHN69821.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 KHN69823.1 - 4.6e-42 143.1 0.4 5.3e-42 142.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 KHN69823.1 - 1.8e-19 69.6 0.2 2.3e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KHN69823.1 - 5.1e-18 65.7 0.3 7.6e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KHN69823.1 - 4.3e-10 39.3 0.2 2.1e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN69823.1 - 1.3e-07 31.5 0.3 2e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KHN69823.1 - 3.9e-06 26.1 0.1 4.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KHN69823.1 - 3.6e-05 23.0 0.1 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KHN69823.1 - 0.0015 18.0 0.2 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KHN69823.1 - 0.0027 17.3 0.1 0.046 13.2 0.0 2.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 KHN69823.1 - 0.0038 16.5 0.4 0.062 12.5 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 KHN69823.1 - 0.0039 17.0 0.3 0.01 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KHN69823.1 - 0.0042 16.7 0.2 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KHN69823.1 - 0.01 15.9 0.1 0.026 14.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KHN69823.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KHN69823.1 - 0.036 12.8 0.5 0.11 11.2 0.1 1.9 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 KHN69823.1 - 0.045 12.8 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 KHN69823.1 - 0.049 12.8 0.2 0.14 11.3 0.1 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 G-alpha PF00503.15 KHN69823.1 - 0.094 11.3 0.2 0.17 10.5 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit LRR_4 PF12799.2 KHN69825.1 - 1.2e-16 59.8 11.3 3e-09 36.2 3.8 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KHN69825.1 - 6.6e-15 54.6 9.6 6.3e-09 35.4 2.3 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KHN69825.1 - 4.9e-09 34.9 15.0 0.022 14.7 0.2 6.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KHN69825.1 - 4.2e-08 32.1 10.0 0.34 11.3 0.0 5.8 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KHN69825.1 - 0.0033 17.3 11.9 0.27 11.3 0.5 4.7 4 1 1 5 5 5 2 Leucine Rich repeat PARP_reg PF02877.9 KHN69825.1 - 0.021 14.4 0.0 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain LRR_4 PF12799.2 KHN69826.1 - 4.8e-34 115.4 42.7 7.9e-07 28.5 0.3 7.7 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KHN69826.1 - 2.7e-31 107.1 36.0 1.2e-07 31.4 0.2 6.1 2 1 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 KHN69826.1 - 2.1e-19 66.5 46.4 0.031 14.2 0.3 12.0 13 0 0 13 13 13 8 Leucine Rich Repeat LRR_9 PF14580.1 KHN69826.1 - 4.9e-09 35.9 13.4 0.00016 21.3 2.8 3.2 1 1 2 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 KHN69826.1 - 1.7e-06 27.2 27.8 2.9 8.4 0.1 11.1 11 1 0 11 11 11 2 Leucine rich repeat LRR_6 PF13516.1 KHN69826.1 - 6.5e-05 22.5 31.3 2.5 8.4 0.0 10.6 11 1 1 12 12 12 2 Leucine Rich repeat AAA PF00004.24 KHN69828.1 - 8.1e-05 22.8 2.0 0.0015 18.7 1.4 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KHN69828.1 - 0.004 17.1 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KHN69828.1 - 0.006 16.0 0.2 0.03 13.7 0.0 1.9 1 1 0 2 2 2 1 IstB-like ATP binding protein DUF2075 PF09848.4 KHN69828.1 - 0.0072 15.3 2.0 0.99 8.3 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KHN69828.1 - 0.0084 16.2 4.3 0.24 11.5 0.1 3.5 4 1 1 5 5 5 1 AAA domain KAP_NTPase PF07693.9 KHN69828.1 - 0.015 14.3 0.1 0.23 10.4 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain DEAD PF00270.24 KHN69828.1 - 0.017 14.5 0.2 0.087 12.3 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_11 PF13086.1 KHN69828.1 - 0.028 14.0 0.8 0.054 13.0 0.6 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KHN69828.1 - 0.038 13.9 0.0 5.4 6.9 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KHN69828.1 - 0.045 13.5 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KHN69828.1 - 0.064 13.4 1.2 0.18 11.9 0.1 2.3 2 1 1 3 3 3 0 RNA helicase AAA_30 PF13604.1 KHN69828.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 KHN69829.1 - 1.3e-30 106.0 17.0 1.3e-30 106.0 11.8 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.20 KHN69829.1 - 0.029 14.5 5.5 0.029 14.5 3.8 2.2 1 1 1 2 2 2 0 Plexin repeat Yip1 PF04893.12 KHN69829.1 - 0.23 10.9 11.8 0.73 9.3 0.8 2.2 2 0 0 2 2 2 0 Yip1 domain DUF1282 PF06930.7 KHN69829.1 - 0.91 9.1 8.7 0.81 9.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) COX2_TM PF02790.10 KHN69829.1 - 1.2 9.1 6.1 8.8 6.3 0.7 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain HTH_9 PF08221.6 KHN69831.1 - 1.2e-17 63.5 0.3 1.2e-15 57.1 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TrmB PF01978.14 KHN69831.1 - 5.3e-05 22.8 0.1 2.9 7.6 0.0 4.3 4 1 0 4 4 4 2 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 KHN69831.1 - 0.00038 19.9 0.7 0.051 13.0 0.1 2.7 2 1 0 2 2 2 2 TFIIE alpha subunit Anti-adapt_IraP PF10796.4 KHN69832.1 - 0.023 15.0 1.5 0.075 13.4 1.1 2.0 1 1 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein DUF3818 PF12825.2 KHN69832.1 - 0.13 10.9 3.7 0.22 10.1 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF1136 PF06582.7 KHN69832.1 - 1.4 8.7 7.0 8.8 6.1 1.2 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) IncA PF04156.9 KHN69832.1 - 3.4 7.2 7.2 5.5 6.5 5.0 1.3 1 0 0 1 1 1 0 IncA protein DUF241 PF03087.9 KHN69832.1 - 4.1 6.8 11.6 1.5 8.2 5.9 1.9 2 1 0 2 2 2 0 Arabidopsis protein of unknown function TAF4 PF05236.9 KHN69833.1 - 4.7e-40 137.5 6.5 6.1e-40 137.1 4.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF1307 PF06998.6 KHN69833.1 - 0.022 14.8 1.6 0.045 13.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) Abi_2 PF07751.6 KHN69833.1 - 0.055 13.6 2.9 0.099 12.8 2.0 1.4 1 0 0 1 1 1 0 Abi-like protein bZIP_2 PF07716.10 KHN69834.1 - 0.039 13.7 1.5 0.11 12.3 1.1 1.7 1 0 0 1 1 1 0 Basic region leucine zipper YopJ PF03421.11 KHN69834.1 - 0.067 13.0 0.7 0.073 12.9 0.5 1.1 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DUF2968 PF11180.3 KHN69834.1 - 0.11 11.8 0.2 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GvpK PF05121.7 KHN69834.1 - 0.3 10.9 4.5 0.97 9.2 0.6 2.2 1 1 1 2 2 2 0 Gas vesicle protein K Gp-FAR-1 PF05823.7 KHN69834.1 - 0.42 10.5 3.9 3.5 7.5 2.7 2.1 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FlaC_arch PF05377.6 KHN69834.1 - 0.73 9.7 5.5 0.71 9.8 1.2 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF3294 PF07957.6 KHN69834.1 - 2.9 7.3 7.1 0.74 9.2 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3294) CH PF00307.26 KHN69836.1 - 4.2e-43 145.7 0.0 5.8e-21 74.5 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KHN69836.1 - 3.9e-13 48.8 0.1 1.5e-07 30.9 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain GARS_N PF02844.10 KHN69836.1 - 0.087 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Drf_FH3 PF06367.11 KHN69836.1 - 1.6 8.0 10.7 0.099 12.0 1.8 2.8 3 0 0 3 3 3 0 Diaphanous FH3 Domain RhoGAP PF00620.22 KHN69837.1 - 8.1e-19 67.7 0.3 2.6e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain RVT_1 PF00078.22 KHN69838.1 - 1.6e-16 60.3 0.1 1.2e-15 57.4 0.0 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.3 KHN69838.1 - 1.7e-16 60.3 14.4 1.7e-16 60.3 9.9 2.1 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain PPR_1 PF12854.2 KHN69839.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat Proteasome PF00227.21 KHN69840.1 - 4.5e-28 97.8 0.2 5.4e-28 97.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KHN69840.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature DWNN PF08783.6 KHN69841.1 - 1.4e-22 79.4 0.1 2.4e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KHN69841.1 - 5.3e-06 25.8 1.8 1.6e-05 24.2 1.2 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_4 PF15227.1 KHN69841.1 - 0.0005 19.8 10.0 0.0005 19.8 6.9 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KHN69841.1 - 0.0019 17.9 14.4 0.0019 17.9 10.0 2.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-CCHC PF00098.18 KHN69841.1 - 0.0089 15.9 4.2 0.0089 15.9 2.9 3.1 3 0 0 3 3 3 1 Zinc knuckle ArfGap PF01412.13 KHN69841.1 - 0.021 14.6 4.8 0.021 14.6 3.3 2.4 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf zf-RING_UBOX PF13445.1 KHN69841.1 - 0.046 13.4 9.9 0.17 11.6 6.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCHC_3 PF13917.1 KHN69841.1 - 0.13 12.0 0.4 0.13 12.0 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle SEO_C PF14577.1 KHN69841.1 - 0.32 10.3 3.5 7.6 5.8 0.1 2.2 2 0 0 2 2 2 0 Sieve element occlusion C-terminus Rubredoxin PF00301.15 KHN69841.1 - 0.73 9.7 9.7 2.5 8.0 0.0 4.0 4 0 0 4 4 4 0 Rubredoxin zf-C3HC4_2 PF13923.1 KHN69841.1 - 5.3 7.1 28.2 0.051 13.6 11.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN69841.1 - 7.6 6.2 22.6 0.049 13.3 8.8 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NOC3p PF07540.6 KHN69842.1 - 2.3e-17 63.0 0.3 5.4e-17 61.8 0.2 1.7 1 0 0 1 1 1 1 Nucleolar complex-associated protein NOB1_Zn_bind PF08772.6 KHN69843.1 - 8.8e-10 38.2 3.5 1.8e-09 37.2 2.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Phospholip_A2_2 PF05826.7 KHN69843.1 - 0.0085 16.0 2.1 0.015 15.2 1.5 1.4 1 0 0 1 1 1 1 Phospholipase A2 CBFD_NFYB_HMF PF00808.18 KHN69844.1 - 3e-05 23.9 1.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ApoL PF05461.6 KHN69844.1 - 0.0021 17.3 0.7 0.0022 17.3 0.5 1.0 1 0 0 1 1 1 1 Apolipoprotein L DUF1268 PF06896.6 KHN69844.1 - 0.05 13.9 1.9 0.21 11.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1268) NUC153 PF08159.7 KHN69845.1 - 1.2e-10 40.7 0.6 1.2e-10 40.7 0.4 1.9 2 0 0 2 2 2 1 NUC153 domain BRAP2 PF07576.7 KHN69845.1 - 0.048 13.2 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 BRCA1-associated protein 2 Ribosomal_L39 PF00832.15 KHN69846.1 - 1.3e-13 50.1 6.5 1.6e-13 49.8 4.5 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein mRNA_cap_enzyme PF01331.14 KHN69847.1 - 1.2e-28 100.0 2.2 5.3e-28 98.0 1.5 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KHN69847.1 - 2.1e-07 31.1 0.3 2.6e-06 27.6 0.2 2.5 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KHN69847.1 - 0.00049 19.5 0.6 0.18 11.1 0.4 3.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SNF2_N PF00176.18 KHN69848.1 - 7.4e-61 205.5 0.1 2.8e-60 203.6 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KHN69848.1 - 2.1e-15 56.3 0.0 6.1e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69848.1 - 9.9e-08 32.0 2.0 2.5e-06 27.4 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KHN69848.1 - 0.00024 20.6 0.0 0.00066 19.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cys_rich_FGFR PF00839.12 KHN69848.1 - 0.11 12.4 1.7 2.2 8.2 0.3 2.8 2 0 0 2 2 2 0 Cysteine rich repeat Adenosine_kin PF04008.9 KHN69849.1 - 0.044 13.2 0.1 0.092 12.2 0.1 1.5 1 0 0 1 1 1 0 Adenosine specific kinase DNA_pol_B PF00136.16 KHN69851.1 - 2.2e-133 445.4 1.3 2.2e-133 445.4 0.9 1.5 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KHN69851.1 - 5.8e-65 219.2 0.6 1.6e-64 217.8 0.4 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KHN69851.1 - 4.4e-15 55.4 9.6 9.5e-15 54.3 6.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 KHN69851.1 - 0.0021 17.6 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KHN69851.1 - 0.028 14.2 0.0 0.15 11.8 0.0 2.2 1 1 0 1 1 1 0 RNase_H superfamily DNA_pol_A_exo1 PF01612.15 KHN69851.1 - 0.095 12.1 0.0 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 3'-5' exonuclease Histone PF00125.19 KHN69852.1 - 7.9e-12 45.1 0.1 1.1e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KHN69852.1 - 0.00019 21.2 0.0 0.0003 20.6 0.0 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 KHN69852.1 - 0.00023 21.1 0.2 0.00047 20.1 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KHN69852.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KHN69852.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 KHN69852.1 - 0.023 14.4 0.1 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 KHN69852.1 - 0.22 10.7 0.2 0.22 10.7 0.1 1.4 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Histone PF00125.19 KHN69853.1 - 5e-27 93.8 0.0 7.3e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KHN69853.1 - 2.8e-06 27.3 0.0 4.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 KHN69853.1 - 0.0055 16.8 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 KHN69853.1 - 0.043 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) LRR_4 PF12799.2 KHN69854.1 - 1e-22 79.2 21.5 6.8e-08 31.9 1.6 5.7 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KHN69854.1 - 8e-16 57.5 14.3 7.2e-08 32.0 0.8 4.2 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 KHN69854.1 - 1.4e-10 39.6 23.2 0.45 10.7 0.0 8.7 6 2 2 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.1 KHN69854.1 - 1.1e-08 34.2 18.8 0.086 12.9 0.0 7.3 7 2 1 8 8 8 4 Leucine Rich repeat LRR_7 PF13504.1 KHN69854.1 - 1.5e-08 33.5 10.3 4.6 7.8 0.0 7.8 7 1 1 8 8 8 3 Leucine rich repeat LRR_9 PF14580.1 KHN69854.1 - 0.00025 20.6 12.7 0.0011 18.5 1.6 2.9 1 1 2 3 3 3 2 Leucine-rich repeat MS_channel PF00924.13 KHN69855.1 - 1.7e-06 27.5 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Cpn60_TCP1 PF00118.19 KHN69856.1 - 1.8e-119 399.5 5.7 2.1e-119 399.3 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nic96 PF04097.9 KHN69857.1 - 4.7e-15 54.7 0.1 1.2e-12 46.7 0.0 2.9 2 1 0 2 2 2 2 Nup93/Nic96 DUF2439 PF10382.4 KHN69859.1 - 9.4e-13 48.1 1.3 9.4e-13 48.1 0.9 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2439) PLA2_B PF01735.13 KHN69859.1 - 0.00073 17.8 2.3 0.00082 17.6 1.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Noc2 PF03715.8 KHN69860.1 - 9.7e-15 54.1 3.7 1.3e-14 53.8 2.6 1.2 1 0 0 1 1 1 1 Noc2p family DUF2013 PF09431.5 KHN69860.1 - 0.63 9.7 5.6 0.75 9.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) DnaJ PF00226.26 KHN69861.1 - 1.6e-08 34.1 0.1 5.3e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.1 KHN69861.1 - 0.00012 22.3 0.0 0.34 11.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_S30 PF01577.11 KHN69861.1 - 0.057 12.8 7.5 0.09 12.1 5.2 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease DapH_N PF08503.5 KHN69861.1 - 0.22 11.6 2.5 0.45 10.6 0.1 2.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal Ribosomal_S14 PF00253.16 KHN69862.1 - 6.2e-13 47.9 2.1 7.3e-13 47.6 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S7 PF00177.16 KHN69864.1 - 5.2e-35 120.1 2.2 6.5e-35 119.8 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Doppel PF11466.3 KHN69865.1 - 0.045 13.3 0.1 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Prion-like protein Doppel RRM_1 PF00076.17 KHN69866.1 - 0.0022 17.6 0.2 0.062 12.9 0.0 2.7 2 2 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69866.1 - 0.0095 15.8 0.4 0.097 12.6 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ERO1 PF04137.10 KHN69867.1 - 6.2e-25 87.9 5.5 1.5e-23 83.3 3.8 2.5 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TFIIS_M PF07500.9 KHN69868.1 - 5.8e-21 74.7 1.8 1.1e-20 73.8 1.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KHN69868.1 - 1.2e-17 63.1 8.1 1.1e-16 60.1 4.8 2.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) KH_1 PF00013.24 KHN69869.1 - 2.8e-07 30.0 0.7 7.9e-07 28.6 0.1 2.0 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KHN69869.1 - 1.4e-05 24.6 1.4 0.00036 20.1 0.3 2.7 2 1 1 3 3 3 1 KH domain DUF749 PF05370.6 KHN69869.1 - 0.016 15.1 0.0 0.64 9.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF749) B56 PF01603.15 KHN69870.1 - 8.4e-24 83.9 0.5 2.1e-23 82.5 0.5 1.4 2 0 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sugar_tr PF00083.19 KHN69871.1 - 5.3e-37 127.4 38.8 1.7e-32 112.5 26.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KHN69871.1 - 3.4e-11 42.4 43.1 2.4e-08 33.1 12.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 KHN69872.1 - 2.6e-06 27.3 0.4 8.2e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF313 PF03754.8 KHN69872.1 - 0.012 15.5 0.7 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF313) Eapp_C PF10238.4 KHN69872.1 - 1.8 8.4 10.3 13 5.6 7.2 2.4 1 1 0 1 1 1 0 E2F-associated phosphoprotein Mad3_BUB1_I PF08311.7 KHN69873.1 - 2.2e-05 24.2 0.6 5.4e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 DUF3641 PF12345.3 KHN69873.1 - 0.019 14.8 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3641) Spt20 PF12090.3 KHN69873.1 - 1.8 7.8 4.0 18 4.5 0.1 2.3 2 0 0 2 2 2 0 Spt20 family OB_NTP_bind PF07717.11 KHN69874.1 - 4.6e-10 39.3 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KHN69874.1 - 1.7e-08 34.2 0.0 4.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KHN69874.1 - 1.3e-07 31.2 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KHN69874.1 - 5.7e-06 26.0 0.0 0.092 12.3 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_22 PF13401.1 KHN69874.1 - 5.1e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KHN69874.1 - 0.00018 21.3 0.0 0.0022 17.8 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KHN69874.1 - 0.00024 21.0 0.0 0.00094 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KHN69874.1 - 0.0039 16.4 0.0 0.0096 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 KHN69874.1 - 0.024 14.1 0.0 0.08 12.4 0.0 1.9 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 KHN69874.1 - 0.035 14.3 0.1 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 KHN69874.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 KHN69874.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KHN69874.1 - 0.066 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.9 KHN69874.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase Adeno_IVa2 PF02456.10 KHN69874.1 - 0.069 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Rad17 PF03215.10 KHN69874.1 - 0.077 11.6 0.1 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KHN69874.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF427 PF04248.7 KHN69874.1 - 0.13 11.9 0.1 22 4.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF427) zf-DHHC PF01529.15 KHN69875.1 - 1.9e-32 112.0 16.8 1.9e-32 112.0 11.6 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-AN1 PF01428.11 KHN69876.1 - 3.7e-11 42.7 11.1 7.2e-11 41.7 7.7 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger NinF PF05810.7 KHN69876.1 - 0.95 9.3 5.5 1.8 8.4 3.8 1.5 1 0 0 1 1 1 0 NinF protein Ssl1 PF04056.9 KHN69877.1 - 5.3e-25 88.1 0.0 7.8e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KHN69877.1 - 0.18 11.8 26.3 0.037 14.0 11.8 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain Y_phosphatase PF00102.22 KHN69879.1 - 9.9e-21 74.1 0.0 1.9e-19 69.9 0.0 2.0 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KHN69879.1 - 2.8e-06 26.9 0.1 8.1e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KHN69879.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KHN69879.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PC_rep PF01851.17 KHN69880.1 - 6.5e-10 38.6 2.2 0.013 15.6 0.0 6.6 8 0 0 8 8 8 3 Proteasome/cyclosome repeat Lipase_3 PF01764.20 KHN69881.1 - 2.2e-19 69.4 0.0 4.1e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KHN69881.1 - 0.016 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KHN69881.1 - 0.11 11.8 0.0 0.31 10.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KHN69881.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L27e PF01777.13 KHN69882.1 - 7.1e-07 29.2 1.2 1.2e-06 28.5 0.8 1.4 1 0 0 1 1 1 1 Ribosomal L27e protein family Tautomerase PF01361.16 KHN69882.1 - 0.025 14.2 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme KOW PF00467.24 KHN69882.1 - 0.037 13.7 1.1 0.084 12.6 0.7 1.5 1 0 0 1 1 1 0 KOW motif YjeF_N PF03853.10 KHN69882.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.3 1 1 0 1 1 1 0 YjeF-related protein N-terminus Med11 PF10280.4 KHN69883.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.7 1 1 0 1 1 1 0 Mediator complex protein DNA_topoisoIV PF00521.15 KHN69884.1 - 1.6e-121 406.0 0.2 2.7e-121 405.3 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KHN69884.1 - 1.6e-30 105.5 0.1 4.1e-30 104.2 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KHN69884.1 - 6.9e-13 48.4 0.0 3.1e-12 46.3 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KHN69884.1 - 3.1e-09 36.5 0.0 7.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KHN69884.1 - 0.00074 19.1 0.4 0.00074 19.1 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_10 PF14788.1 KHN69885.1 - 0.072 12.7 1.1 0.15 11.7 0.8 1.5 1 0 0 1 1 1 0 EF hand Ninjurin PF04923.7 KHN69887.1 - 1.5 8.5 10.4 0.29 10.8 0.5 3.2 1 1 2 3 3 3 0 Ninjurin ABC2_membrane_4 PF12730.2 KHN69887.1 - 3.1 6.8 21.6 2.3 7.3 5.8 3.3 2 1 0 2 2 2 0 ABC-2 family transporter protein MARVEL PF01284.18 KHN69887.1 - 4.1 7.2 11.9 0.33 10.7 3.2 2.8 1 1 2 3 3 3 0 Membrane-associating domain MgtE PF01769.11 KHN69888.1 - 3.1e-12 46.9 28.0 8.8e-09 35.7 4.7 2.7 3 0 0 3 3 3 2 Divalent cation transporter HSF_DNA-bind PF00447.12 KHN69889.1 - 1.6e-14 53.9 0.0 2.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF919 PF06034.6 KHN69890.1 - 0.045 13.3 0.3 0.18 11.4 0.2 2.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Herpes_LMP2 PF07415.6 KHN69891.1 - 0.087 11.3 0.2 0.092 11.3 0.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein JAB PF01398.16 KHN69892.1 - 2.9e-21 75.3 0.0 7.3e-21 74.0 0.0 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KHN69892.1 - 7.9e-16 58.1 0.1 1.8e-15 57.0 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Gpi1 PF05024.10 KHN69893.1 - 9e-05 22.2 2.8 9e-05 22.2 1.9 2.3 1 1 1 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DUF912 PF06024.7 KHN69893.1 - 1.4 9.0 4.2 1.2 9.2 1.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sec10 PF07393.6 KHN69894.1 - 3.4e-09 35.4 0.4 7.3e-09 34.3 0.3 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec10 Ribosomal_S2 PF00318.15 KHN69895.1 - 1.8e-27 95.9 0.1 9.4e-14 51.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 RrnaAD PF00398.15 KHN69896.1 - 2.3e-53 180.9 0.0 2.8e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KHN69896.1 - 2.4e-10 40.4 0.0 3.6e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KHN69896.1 - 1.2e-05 25.8 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KHN69896.1 - 1.5e-05 25.3 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KHN69896.1 - 3.8e-05 23.1 0.0 7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KHN69896.1 - 8.4e-05 22.8 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KHN69896.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KHN69896.1 - 0.0045 16.5 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 KHN69896.1 - 0.0061 17.0 0.0 0.024 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN69896.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KHN69896.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 KHN69896.1 - 0.036 13.1 0.0 0.088 11.9 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 KHN69896.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spermine_synth PF01564.12 KHN69896.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase CMAS PF02353.15 KHN69896.1 - 0.077 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PQQ_3 PF13570.1 KHN69897.1 - 0.0033 17.6 0.1 1.3 9.3 0.1 3.6 3 0 0 3 3 3 1 PQQ-like domain Kelch_6 PF13964.1 KHN69897.1 - 0.015 15.4 2.3 0.2 11.9 0.0 3.5 4 1 1 5 5 5 0 Kelch motif Hydrolase_3 PF08282.7 KHN69897.1 - 0.035 13.6 0.3 0.046 13.3 0.2 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.22 KHN69898.1 - 1.5e-24 86.8 0.0 3e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KHN69898.1 - 1.2e-08 34.5 5.4 1.6e-08 34.0 2.2 2.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KHN69898.1 - 3.5e-07 30.4 1.5 0.0014 18.6 0.5 2.9 2 1 0 3 3 3 2 AAA domain ABC_membrane PF00664.18 KHN69898.1 - 9.1e-06 25.2 12.9 1.4e-05 24.6 9.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_17 PF13207.1 KHN69898.1 - 0.0056 17.4 0.5 0.016 15.9 0.2 2.1 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 KHN69898.1 - 0.0057 15.5 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 KHN69898.1 - 0.028 13.5 0.0 0.083 11.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 KHN69898.1 - 0.029 14.6 0.2 0.077 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KHN69898.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KHN69898.1 - 0.14 12.4 1.5 0.26 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain Yip1 PF04893.12 KHN69898.1 - 0.37 10.2 5.6 0.46 9.9 0.2 2.5 2 1 0 2 2 2 0 Yip1 domain PTH2 PF01981.11 KHN69899.1 - 2.4e-05 23.9 0.0 3.3e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2268 PF10026.4 KHN69899.1 - 0.12 11.7 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) HECT PF00632.20 KHN69900.1 - 9.1e-78 261.5 1.6 1.5e-77 260.8 1.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) KH_1 PF00013.24 KHN69902.1 - 0.00012 21.6 1.3 0.00042 19.8 0.1 2.4 2 0 0 2 2 2 1 KH domain PCI PF01399.22 KHN69902.1 - 0.041 14.1 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 PCI domain KH_3 PF13014.1 KHN69902.1 - 0.057 13.0 0.2 0.9 9.2 0.0 2.5 2 0 0 2 2 2 0 KH domain UAA PF08449.6 KHN69904.1 - 2.2e-49 167.9 20.1 2.8e-49 167.6 13.9 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KHN69904.1 - 0.00047 19.8 18.8 0.00096 18.8 6.4 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KHN69904.1 - 0.039 14.0 19.0 0.039 14.0 3.7 3.3 3 1 0 3 3 3 0 EamA-like transporter family Pcc1 PF09341.5 KHN69905.1 - 0.042 13.8 0.1 0.055 13.5 0.1 1.2 1 1 0 1 1 1 0 Transcription factor Pcc1 SLS PF14611.1 KHN69905.1 - 0.11 11.8 0.2 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Fcf1 PF04900.7 KHN69906.1 - 1.6e-11 44.1 0.3 2.8e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 Fcf1 tRNA-synt_2 PF00152.15 KHN69907.1 - 4e-92 308.5 0.5 5.1e-92 308.1 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 KHN69907.1 - 2.5e-10 39.9 0.2 2.5e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 KHN69907.1 - 1e-05 25.3 0.2 2.1e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KHN69907.1 - 0.013 15.1 0.3 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_M24 PF00557.19 KHN69908.1 - 1.8e-40 138.7 0.0 3e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KHN69908.1 - 3.8e-12 46.8 0.0 8.8e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain zf-RING_2 PF13639.1 KHN69909.1 - 4e-14 52.1 7.0 4e-14 52.1 4.8 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KHN69909.1 - 4.6e-10 39.4 2.8 9.9e-10 38.3 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KHN69909.1 - 4.1e-09 36.3 5.4 4.1e-09 36.3 3.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69909.1 - 4.2e-09 35.9 5.4 4.2e-09 35.9 3.7 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KHN69909.1 - 8.2e-09 34.9 5.2 8.2e-09 34.9 3.6 1.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN69909.1 - 2e-08 33.7 1.8 2e-08 33.7 1.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KHN69909.1 - 6e-05 22.8 2.2 0.00011 21.9 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KHN69909.1 - 0.00085 18.9 2.1 0.0011 18.5 0.5 1.9 1 1 1 2 2 2 1 RING-type zinc-finger RINGv PF12906.2 KHN69909.1 - 0.0072 16.3 3.0 0.027 14.4 2.1 2.0 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KHN69909.1 - 0.013 15.4 8.5 0.32 11.0 5.9 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Rer1 PF03248.8 KHN69909.1 - 0.023 14.2 1.1 0.029 13.9 0.1 1.6 2 0 0 2 2 2 0 Rer1 family zf-C3HC4_4 PF15227.1 KHN69909.1 - 0.076 12.9 6.0 0.49 10.3 4.4 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KHN69909.1 - 0.094 12.3 4.4 0.2 11.2 3.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KHN69909.1 - 0.12 11.9 3.9 0.27 10.8 2.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.6 KHN69909.1 - 0.15 11.8 0.8 0.32 10.8 0.6 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Met_10 PF02475.11 KHN69910.1 - 2.1e-49 167.8 0.0 3.7e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 KHN69910.1 - 1.2e-07 31.4 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.9 KHN69910.1 - 4.7e-07 29.3 0.0 7.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KHN69910.1 - 1.6e-06 28.6 0.0 4.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KHN69910.1 - 5.9e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN69910.1 - 6.5e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KHN69910.1 - 0.00025 20.2 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 KHN69910.1 - 0.00035 19.3 0.0 0.00056 18.7 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.9 KHN69910.1 - 0.00087 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.1 KHN69910.1 - 0.0012 18.6 0.0 0.0035 17.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KHN69910.1 - 0.0012 18.3 0.7 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 KHN69910.1 - 0.0053 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 FmrO PF07091.6 KHN69910.1 - 0.0064 15.5 0.0 0.0098 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TRM PF02005.11 KHN69910.1 - 0.011 14.7 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_11 PF08241.7 KHN69910.1 - 0.11 12.9 0.0 0.45 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UQ_con PF00179.21 KHN69911.1 - 6.2e-46 155.3 0.0 7.1e-46 155.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_S17 PF00366.15 KHN69912.1 - 8.4e-23 80.1 1.8 1.4e-22 79.4 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Pribosyltran_N PF13793.1 KHN69912.1 - 0.069 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Lipase_3 PF01764.20 KHN69913.1 - 9.1e-08 31.8 0.4 2.2e-07 30.5 0.1 1.9 2 1 0 2 2 2 1 Lipase (class 3) DUF2048 PF09752.4 KHN69913.1 - 0.00016 20.7 0.1 0.00022 20.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Cutinase PF01083.17 KHN69913.1 - 0.00094 18.9 0.3 0.002 17.9 0.2 1.5 1 1 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KHN69913.1 - 0.0014 18.4 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KHN69913.1 - 0.0018 17.6 0.2 0.0048 16.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 KHN69913.1 - 0.0086 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KHN69913.1 - 0.0094 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KHN69913.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_8 PF06259.7 KHN69913.1 - 0.031 13.7 0.1 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Esterase PF00756.15 KHN69913.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Glyco_hydro_16 PF00722.16 KHN69913.1 - 0.066 12.5 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DUF676 PF05057.9 KHN69913.1 - 0.07 12.4 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ras PF00071.17 KHN69915.1 - 5.7e-53 178.6 0.3 7.1e-53 178.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN69915.1 - 2.2e-19 70.1 0.0 3.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN69915.1 - 1.3e-16 60.2 0.1 1.8e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KHN69915.1 - 7e-07 28.8 0.3 2.5e-05 23.7 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN69915.1 - 8.9e-06 25.6 0.1 1.4e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KHN69915.1 - 3e-05 23.2 0.0 5.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KHN69915.1 - 0.00026 20.1 0.1 0.00037 19.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 KHN69915.1 - 0.0038 16.4 0.1 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 KHN69915.1 - 0.0058 15.7 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 KHN69915.1 - 0.0099 15.3 0.1 0.07 12.6 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KHN69915.1 - 0.01 15.4 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KHN69915.1 - 0.022 14.2 0.0 0.067 12.7 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KHN69915.1 - 0.025 14.7 0.0 0.096 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KHN69915.1 - 0.037 14.3 0.1 0.08 13.2 0.0 1.6 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 KHN69915.1 - 0.11 11.7 0.2 0.25 10.6 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Chorein_N PF12624.2 KHN69916.1 - 1.8e-23 82.3 0.1 5.3e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 KHN69916.1 - 0.046 12.9 0.1 2.5 7.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1162) Metallophos PF00149.23 KHN69917.1 - 6.8e-42 143.1 0.1 8.5e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rhodanese PF00581.15 KHN69918.1 - 2.4e-13 50.4 0.0 3.9e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF4048 PF13257.1 KHN69918.1 - 0.086 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) PTH2 PF01981.11 KHN69919.1 - 2.9e-31 107.5 0.0 3.7e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Glucosamine_iso PF01182.15 KHN69920.1 - 1e-22 80.8 0.0 1.3e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_L22e PF01776.12 KHN69921.1 - 1.5e-16 60.4 0.0 1.7e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family tRNA-synt_2b PF00587.20 KHN69922.1 - 8.6e-31 106.8 0.0 1.5e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KHN69922.1 - 2.2e-16 59.7 5.7 4e-16 58.9 4.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 KHN69922.1 - 0.015 13.1 0.2 0.019 12.8 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_His PF13393.1 KHN69922.1 - 0.042 12.9 0.0 0.083 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidyl-tRNA synthetase GAS PF13851.1 KHN69922.1 - 0.082 12.0 3.1 0.14 11.3 2.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3086 PF11285.3 KHN69922.1 - 0.18 10.5 1.3 0.34 9.6 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Occludin_ELL PF07303.8 KHN69922.1 - 0.64 10.7 5.3 1.6 9.5 1.5 2.7 2 1 0 2 2 2 0 Occludin homology domain PROCN PF08083.6 KHN69923.1 - 5.5e-119 397.2 12.6 2.4e-114 381.9 4.3 2.3 2 0 0 2 2 2 2 PROCN (NUC071) domain U6-snRNA_bdg PF10596.4 KHN69923.1 - 1.1e-56 190.5 0.2 2.4e-56 189.5 0.1 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.4 KHN69923.1 - 2.9e-41 140.2 0.0 1.8e-40 137.6 0.0 2.4 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.6 KHN69923.1 - 2.6e-33 114.8 0.7 5.8e-33 113.6 0.0 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.4 KHN69923.1 - 7.1e-26 89.8 1.1 2.2e-25 88.3 0.8 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PRP8_domainIV PF12134.3 KHN69923.1 - 1.8e-16 60.1 0.0 4.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 PRP8 domain IV core PROCT PF08084.6 KHN69923.1 - 1.2e-07 31.5 0.5 2.6e-07 30.3 0.1 1.8 2 0 0 2 2 2 1 PROCT (NUC072) domain PRESAN PF09687.5 KHN69924.1 - 0.068 13.2 1.5 0.1 12.6 0.2 1.9 2 1 0 2 2 2 0 Plasmodium RESA N-terminal eIF-6 PF01912.13 KHN69925.1 - 2.7e-74 248.5 1.3 3.4e-74 248.2 0.9 1.1 1 0 0 1 1 1 1 eIF-6 family LSM PF01423.17 KHN69926.1 - 9.3e-15 53.9 0.3 1.2e-14 53.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KHN69926.1 - 0.00025 20.9 0.0 0.00053 19.8 0.0 1.5 1 1 1 2 2 2 1 Ataxin 2 SM domain Glyco_hydro_79n PF03662.9 KHN69927.1 - 0.1 11.2 0.1 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain EF-hand_6 PF13405.1 KHN69928.1 - 7.7e-10 37.8 0.3 0.00076 19.1 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 KHN69928.1 - 8.9e-10 37.1 1.4 1.9e-06 26.7 0.0 4.6 4 1 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KHN69928.1 - 3.2e-08 33.0 0.1 8e-06 25.3 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 KHN69928.1 - 3.4e-08 33.4 0.2 5e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 KHN69928.1 - 2.9e-06 26.3 0.1 0.00023 20.3 0.0 3.6 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 KHN69928.1 - 0.05 13.6 0.0 0.095 12.7 0.0 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 KHN69928.1 - 0.11 12.0 0.1 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Caleosin related protein Nop PF01798.13 KHN69929.1 - 9e-48 161.3 0.7 1.7e-47 160.5 0.5 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KHN69929.1 - 1.5e-19 69.5 0.0 3.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KHN69929.1 - 0.0072 16.4 0.3 0.93 9.6 0.1 3.6 2 1 1 3 3 3 1 NOP5NT (NUC127) domain PAXNEB PF05625.6 KHN69930.1 - 9.9e-23 80.5 0.8 9.7e-18 64.1 0.6 3.9 1 1 0 1 1 1 1 PAXNEB protein Asn_synthase PF00733.16 KHN69931.1 - 4.5e-39 134.4 0.0 3.2e-38 131.6 0.0 2.1 1 1 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 KHN69931.1 - 0.00077 19.0 0.1 0.003 17.0 0.0 2.0 2 0 0 2 2 2 1 PP-loop family MCM PF00493.18 KHN69932.1 - 1.6e-133 444.6 0.3 2.7e-133 443.8 0.2 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KHN69932.1 - 1.3e-20 74.0 0.2 3.2e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KHN69932.1 - 8.4e-10 38.1 0.4 5.8e-08 32.1 0.0 2.9 2 2 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KHN69932.1 - 7.9e-05 22.4 0.0 0.00024 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KHN69932.1 - 0.0028 17.2 0.0 0.0093 15.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KHN69932.1 - 0.0049 16.3 0.0 1.3 8.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF4002 PF13164.1 KHN69935.1 - 0.17 11.9 1.7 6.5 6.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4002) PseudoU_synth_1 PF01416.15 KHN69936.1 - 1.8e-20 73.3 0.1 6.5e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase B5 PF03484.10 KHN69937.1 - 1.6e-21 75.8 0.6 2.3e-15 56.1 0.1 2.9 3 0 0 3 3 3 2 tRNA synthetase B5 domain B3_4 PF03483.12 KHN69937.1 - 6.7e-17 61.4 0.0 1.1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain DSHCT PF08148.7 KHN69938.1 - 9.1e-49 165.1 0.0 2.1e-48 163.9 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KHN69938.1 - 3.1e-20 72.3 0.0 6.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69938.1 - 6.4e-07 29.1 0.0 2.7e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4277 PF14104.1 KHN69938.1 - 3.5e-05 23.9 0.1 0.00015 21.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4277) rRNA_proc-arch PF13234.1 KHN69938.1 - 0.012 14.8 0.0 0.012 14.8 0.0 1.9 2 0 0 2 2 2 0 rRNA-processing arch domain T2SE PF00437.15 KHN69938.1 - 0.022 13.6 0.0 0.06 12.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein SMC_N PF02463.14 KHN69940.1 - 1.2e-53 181.6 0.0 1.8e-53 181.0 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KHN69940.1 - 1.7e-22 79.6 0.0 1e-21 77.1 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KHN69940.1 - 1e-13 51.9 7.6 2.5e-06 27.6 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KHN69940.1 - 6.7e-07 28.7 0.0 1.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KHN69940.1 - 1.3e-06 28.8 62.7 2.2e-06 28.1 19.7 5.7 3 2 0 3 3 2 1 AAA domain AAA_15 PF13175.1 KHN69940.1 - 0.00096 18.3 0.0 0.00096 18.3 0.0 3.6 3 1 0 3 3 2 1 AAA ATPase domain AAA_30 PF13604.1 KHN69940.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain FliD_N PF02465.13 KHN69940.1 - 0.19 12.1 2.3 13 6.2 0.1 3.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AAA_16 PF13191.1 KHN69940.1 - 0.22 11.4 0.2 0.97 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain ACR_tran PF00873.14 KHN69940.1 - 0.34 8.2 0.7 0.53 7.6 0.5 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family ABC_tran PF00005.22 KHN69940.1 - 1 9.6 0.0 1 9.6 0.0 4.5 5 2 0 5 5 5 0 ABC transporter Cas_CXXC_CXXC PF09706.5 KHN69940.1 - 1.7 8.8 6.1 6.6 6.9 0.2 3.7 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) AAA_22 PF13401.1 KHN69940.1 - 1.8 8.6 6.0 12 5.9 0.0 3.7 5 0 0 5 5 4 0 AAA domain Sec66 PF09802.4 KHN69941.1 - 9.3e-07 28.4 1.2 1.5e-06 27.7 0.8 1.4 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF2909 PF11137.3 KHN69941.1 - 0.042 13.5 0.2 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) TFIID-18kDa PF02269.11 KHN69942.1 - 2.5e-20 72.0 0.2 3e-20 71.8 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit EXOSC1 PF10447.4 KHN69943.1 - 0.032 14.1 0.2 0.092 12.7 0.1 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Homeobox PF00046.24 KHN69944.1 - 1.4e-14 53.4 1.9 2.5e-14 52.6 1.3 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KHN69944.1 - 4.2e-06 26.3 0.3 1.2e-05 24.8 0.2 1.8 2 0 0 2 2 2 1 Homeobox KN domain Toxin_66 PF15544.1 KHN69944.1 - 0.062 12.5 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative toxin 66 DUF613 PF04764.7 KHN69944.1 - 0.32 10.8 2.8 0.94 9.4 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF613) SRP54 PF00448.17 KHN69945.1 - 5.5e-69 231.5 0.3 8.7e-69 230.8 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KHN69945.1 - 3.4e-22 78.6 4.0 3.1e-21 75.5 0.0 3.2 2 1 1 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 KHN69945.1 - 9e-12 44.9 0.2 2.4e-11 43.5 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KHN69945.1 - 2e-08 33.9 0.1 5.2e-08 32.5 0.1 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KHN69945.1 - 2.3e-05 24.0 0.1 5.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KHN69945.1 - 0.00029 20.7 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 KHN69945.1 - 0.0007 18.4 0.1 0.0029 16.4 0.0 2.0 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 KHN69945.1 - 0.0079 16.3 0.1 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KHN69945.1 - 0.0092 15.4 0.1 0.078 12.4 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_30 PF13604.1 KHN69945.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KHN69945.1 - 0.021 14.5 0.0 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase SRPRB PF09439.5 KHN69945.1 - 0.024 13.8 0.5 14 4.8 0.0 3.5 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit LacI PF00356.16 KHN69945.1 - 0.029 13.9 0.3 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family AAA_19 PF13245.1 KHN69945.1 - 0.058 13.1 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain TAFH PF07531.9 KHN69945.1 - 0.083 12.5 0.2 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF Gtr1_RagA PF04670.7 KHN69945.1 - 0.12 11.5 1.5 6 5.9 0.2 3.1 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KHN69945.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain POTRA_2 PF08479.6 KHN69945.1 - 0.15 11.7 0.1 10 5.8 0.1 3.5 4 0 0 4 4 4 0 POTRA domain, ShlB-type Myosin_head PF00063.16 KHN69947.1 - 9.3e-232 770.9 4.4 9.3e-232 770.9 3.1 3.9 3 2 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.14 KHN69947.1 - 0.00081 19.0 1.9 0.0021 17.6 1.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 KHN69947.1 - 0.0015 18.5 0.0 0.0052 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KHN69947.1 - 0.018 15.1 0.1 0.38 10.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain SATase_N PF06426.9 KHN69947.1 - 1.1 9.5 5.4 0.37 11.0 0.7 2.7 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Reo_sigmaC PF04582.7 KHN69947.1 - 1.4 8.0 2.6 4.5 6.3 0.3 2.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Ribosomal_L29e PF01779.12 KHN69948.1 - 8.1e-15 54.4 5.6 9.3e-15 54.2 3.9 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Caps_synth PF05704.7 KHN69949.1 - 0.02 14.0 0.2 0.023 13.8 0.2 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TAF1D PF15333.1 KHN69949.1 - 0.066 12.9 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Ribosomal_S27e PF01667.12 KHN69950.1 - 2.7e-11 42.8 3.4 4.5e-11 42.1 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_5 PF13719.1 KHN69950.1 - 1.6 8.3 4.7 14 5.3 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KHN69950.1 - 2.1 8.1 5.1 16 5.3 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3133 PF11331.3 KHN69950.1 - 2.2 7.9 9.4 0.56 9.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3133) Cpn60_TCP1 PF00118.19 KHN69951.1 - 2.4e-52 178.1 5.8 8.8e-51 173.0 2.9 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Homeobox PF00046.24 KHN69952.1 - 1.5e-17 62.9 0.5 2.2e-17 62.4 0.4 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KHN69952.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.7 1 1 0 1 1 1 0 Homeobox KN domain RNA_pol_I_A49 PF06870.7 KHN69953.1 - 0.0098 14.5 0.1 1.6 7.1 0.0 2.2 2 0 0 2 2 2 2 A49-like RNA polymerase I associated factor DUF730 PF05325.6 KHN69953.1 - 0.045 13.5 1.0 0.37 10.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Glycos_transf_2 PF00535.21 KHN69955.1 - 7.3e-28 97.3 0.0 9.2e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KHN69955.1 - 5.4e-15 55.8 0.0 6.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KHN69955.1 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KHN69955.1 - 0.00062 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Topoisom_bac PF01131.15 KHN69956.1 - 2.6e-90 303.1 0.0 3.9e-90 302.5 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 KHN69956.1 - 6.7e-20 70.7 17.9 1.2e-09 37.8 3.2 2.9 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.17 KHN69956.1 - 1.8e-14 53.5 0.0 4.9e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain PTEN_C2 PF10409.4 KHN69957.1 - 0.059 13.1 0.4 0.18 11.5 0.1 1.8 1 1 1 2 2 2 0 C2 domain of PTEN tumour-suppressor protein NHase_alpha PF02979.11 KHN69957.1 - 0.063 12.5 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain DUF1764 PF08576.5 KHN69957.1 - 0.77 10.5 4.9 0.64 10.8 2.5 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Actin PF00022.14 KHN69958.1 - 2e-33 115.4 0.6 2.2e-28 98.7 0.1 3.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.8 KHN69958.1 - 0.0037 15.9 5.4 0.024 13.2 3.7 2.1 1 1 0 1 1 1 1 MreB/Mbl protein GTP_EFTU PF00009.22 KHN69959.1 - 2.3e-41 141.2 0.2 3.4e-41 140.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 KHN69959.1 - 6.1e-10 39.0 0.2 1.9e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 KHN69959.1 - 3.5e-07 30.3 0.1 8.5e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 KHN69959.1 - 7.8e-05 23.1 0.3 0.00056 20.3 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KHN69959.1 - 0.00038 20.3 0.1 0.00095 19.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.18 KHN69959.1 - 0.0047 16.3 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.13 KHN69959.1 - 0.011 14.7 0.2 0.023 13.7 0.1 1.5 1 0 0 1 1 1 0 Septin G-alpha PF00503.15 KHN69959.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SMC_N PF02463.14 KHN69959.1 - 0.095 11.9 0.2 0.37 9.9 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain TP6A_N PF04406.9 KHN69960.1 - 1.6e-08 34.0 0.0 9.6e-08 31.5 0.0 2.3 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 KHN69960.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) UPF0020 PF01170.13 KHN69960.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 B2 PF11473.3 KHN69961.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 RNA binding protein B2 Glyco_transf_15 PF01793.11 KHN69962.1 - 3.6e-126 420.6 13.2 4.6e-126 420.2 9.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4304 PF14137.1 KHN69962.1 - 0.32 11.1 4.1 0.37 10.9 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) tRNA-synt_1 PF00133.17 KHN69963.1 - 8.2e-182 605.3 0.0 3.3e-181 603.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KHN69963.1 - 1.1e-23 83.6 0.3 2.2e-23 82.7 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KHN69963.1 - 1.9e-18 66.3 2.0 2.9e-10 39.3 0.0 5.0 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KHN69963.1 - 1.3e-10 40.8 0.3 1.6e-09 37.3 0.0 2.5 3 0 0 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 KHN69963.1 - 0.0009 18.1 0.0 0.0024 16.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 KHN69963.1 - 0.0017 17.5 0.1 0.49 9.4 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 KHN69963.1 - 0.032 13.3 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PPP5 PF08321.7 KHN69963.1 - 0.06 13.3 1.0 0.18 11.8 0.7 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region UPF0121 PF03661.8 KHN69964.1 - 1.3e-07 31.0 6.3 1.3e-07 31.0 4.3 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF4029 PF13221.1 KHN69964.1 - 1.4 9.3 6.5 0.15 12.4 1.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4029) Transket_pyr PF02779.19 KHN69965.1 - 2e-39 134.9 0.0 2.6e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KHN69965.1 - 8.9e-33 112.8 0.1 4e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain eIF-1a PF01176.14 KHN69966.1 - 2.1e-18 65.5 0.5 3.6e-18 64.7 0.1 1.5 1 1 1 2 2 2 1 Translation initiation factor 1A / IF-1 Aa_trans PF01490.13 KHN69967.1 - 3.2e-35 121.4 41.2 4.5e-35 120.9 28.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1049 PF06305.6 KHN69967.1 - 0.063 12.7 0.4 0.37 10.3 0.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Bacteriocin_IId PF09221.5 KHN69967.1 - 0.66 9.9 4.9 3.6 7.5 0.2 2.9 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like SWIB PF02201.13 KHN69968.1 - 2.4e-07 30.3 0.0 6.7e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Ufd2P_core PF10408.4 KHN69969.1 - 5.6e-57 193.3 23.0 2.5e-38 131.7 8.5 3.6 3 2 1 4 4 4 3 Ubiquitin elongating factor core U-box PF04564.10 KHN69969.1 - 2.3e-13 49.9 0.3 5.1e-13 48.7 0.2 1.5 1 0 0 1 1 1 1 U-box domain AAA_23 PF13476.1 KHN69969.1 - 0.083 13.2 4.6 0.048 13.9 1.0 2.1 2 0 0 2 2 2 0 AAA domain FlxA PF14282.1 KHN69969.1 - 0.18 11.7 3.2 0.31 11.0 2.2 1.3 1 0 0 1 1 1 0 FlxA-like protein TMF_TATA_bd PF12325.3 KHN69969.1 - 0.26 11.0 6.2 2.5 7.8 0.9 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 KHN69969.1 - 1.5 8.3 6.4 3.8 7.0 4.3 1.8 1 1 0 1 1 1 0 Septum formation initiator Thymidylate_kin PF02223.12 KHN69970.1 - 3.6e-39 134.0 0.1 4.4e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KHN69970.1 - 4.8e-08 33.1 0.0 6.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KHN69970.1 - 8.3e-05 22.8 0.2 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.1 KHN69970.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KHN69970.1 - 0.0023 17.1 0.0 0.0053 15.9 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 KHN69970.1 - 0.011 15.6 0.2 0.4 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 KHN69970.1 - 0.018 14.2 0.2 0.049 12.8 0.0 1.9 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_17 PF13207.1 KHN69970.1 - 0.031 15.0 0.2 0.22 12.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KHN69970.1 - 0.074 12.1 0.0 8.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 KHN69970.1 - 0.093 12.5 0.0 0.23 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KHN69970.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase HUN PF08729.5 KHN69971.1 - 2.4e-11 43.3 0.3 2.4e-11 43.3 0.2 2.7 3 0 0 3 3 3 1 HPC2 and ubinuclein domain Brix PF04427.13 KHN69972.1 - 1.2e-06 28.3 0.5 1.6e-06 27.9 0.3 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.27 KHN69973.1 - 1.5e-29 100.7 10.2 1.4e-09 37.4 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KHN69973.1 - 0.00096 18.0 5.7 0.093 11.4 0.5 2.4 2 1 0 2 2 2 2 Nup133 N terminal like Curlin_rpt PF07012.7 KHN69973.1 - 0.022 14.4 1.0 0.05 13.3 0.7 1.6 1 0 0 1 1 1 0 Curlin associated repeat Nbas_N PF15492.1 KHN69973.1 - 0.023 13.7 0.6 0.17 10.9 0.1 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SAC3_GANP PF03399.11 KHN69974.1 - 3.8e-08 33.1 0.2 9e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Crust_neurohorm PF01147.12 KHN69974.1 - 0.022 14.0 0.0 0.075 12.3 0.0 2.0 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Acyltransferase PF01553.16 KHN69976.1 - 1.1e-09 37.8 0.1 2.1e-09 36.9 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase DSHCT PF08148.7 KHN69977.1 - 5.7e-41 139.7 0.2 2.4e-40 137.7 0.0 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KHN69977.1 - 2.8e-20 72.4 0.0 5.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN69977.1 - 1.7e-06 27.7 0.0 4.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN69977.1 - 0.0073 16.1 0.0 0.04 13.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RRM_1 PF00076.17 KHN69978.1 - 1e-14 53.9 0.5 2e-06 27.3 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN69978.1 - 1.5e-13 50.5 0.1 5.3e-05 23.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN69978.1 - 1.7e-06 27.7 0.4 0.069 13.0 0.2 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 KHN69978.1 - 0.0044 16.7 0.1 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Ribosomal_L32e PF01655.13 KHN69979.1 - 9.2e-41 138.3 0.4 1.1e-40 138.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 NDUF_C2 PF06374.6 KHN69980.1 - 0.063 13.2 0.2 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) MMS1_N PF10433.4 KHN69980.1 - 0.078 11.1 0.9 0.51 8.4 0.2 2.2 1 1 1 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term CBF PF03914.12 KHN69982.1 - 0.00057 19.3 0.1 0.00091 18.7 0.1 1.3 1 0 0 1 1 1 1 CBF/Mak21 family VSP PF03302.8 KHN69983.1 - 0.17 10.4 1.6 0.24 10.0 1.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TF_Zn_Ribbon PF08271.7 KHN69983.1 - 0.26 10.6 2.5 0.62 9.4 1.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding S10_plectin PF03501.10 KHN69984.1 - 9.8e-17 60.6 0.2 1e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Clp1 PF06807.9 KHN69984.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Baculo_11_kDa PF06143.6 KHN69985.1 - 0.032 13.6 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF3671 PF12420.3 KHN69985.1 - 2.9 7.9 6.8 5.1 7.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function Rad21_Rec8_N PF04825.8 KHN69986.1 - 2.2e-05 24.3 0.1 3.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KHN69986.1 - 0.0081 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein BNIP2 PF12496.3 KHN69986.1 - 2.2 8.4 5.4 3.5 7.8 0.7 2.2 1 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Ribosomal_L13 PF00572.13 KHN69987.1 - 7.5e-17 61.5 0.3 1.5e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 YL1_C PF08265.6 KHN69988.1 - 3.1e-12 45.8 2.1 5.2e-12 45.1 1.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RnaseA PF00074.15 KHN69988.1 - 0.14 12.4 0.6 0.17 12.1 0.4 1.2 1 0 0 1 1 1 0 Pancreatic ribonuclease RNA_pol_Rpb1_5 PF04998.12 KHN69989.1 - 9.4e-82 274.3 0.0 4.2e-80 268.9 0.0 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KHN69989.1 - 8e-60 201.5 1.0 2e-59 200.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KHN69989.1 - 2e-34 118.6 1.2 1.8e-33 115.4 0.3 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KHN69989.1 - 1.7e-32 112.9 2.0 2.1e-30 106.1 0.0 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KHN69989.1 - 1.2e-19 69.9 0.0 1.2e-19 69.9 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 KHN69989.1 - 1.5 6.6 13.2 2.3 6.0 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KHN69989.1 - 7 4.5 11.2 11 3.9 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein R_equi_Vir PF05526.6 KHN69990.1 - 0.1 12.2 1.1 0.37 10.4 0.6 2.0 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF272 PF03312.10 KHN69991.1 - 0.0058 16.8 2.3 0.0065 16.6 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF272) Skp1_POZ PF03931.10 KHN69992.1 - 1.3e-06 28.3 0.7 6.1e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain zf-RING_UBOX PF13445.1 KHN69993.1 - 1.8e-12 46.7 2.1 4.4e-12 45.5 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KHN69993.1 - 0.021 14.2 1.7 0.045 13.2 1.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 KHN69993.1 - 0.047 13.5 4.6 0.12 12.2 3.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KHN69993.1 - 0.066 13.0 3.1 0.15 11.8 2.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 KHN69993.1 - 0.13 12.3 1.9 0.41 10.7 1.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KHN69993.1 - 0.36 10.5 3.1 1.1 8.9 2.1 1.9 1 1 0 1 1 1 0 zinc-RING finger domain RyR PF02026.11 KHN69994.1 - 0.02 14.9 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 RyR domain Vhr1 PF04001.8 KHN69994.1 - 0.068 13.0 0.3 0.075 12.9 0.2 1.1 1 0 0 1 1 1 0 Transcription factor Vhr1 TBP PF00352.16 KHN69995.1 - 1.4e-69 229.4 1.0 4.9e-35 118.7 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KHN69995.1 - 2.3e-05 24.3 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.1 KHN69995.1 - 0.14 11.8 0.8 0.95 9.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DENN PF02141.16 KHN69997.1 - 1.7e-09 37.6 0.8 3.9e-09 36.4 0.6 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF321 PF03778.8 KHN69997.1 - 1.3 8.4 3.8 5.3 6.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF321) Na_H_Exchanger PF00999.16 KHN69998.1 - 4.3e-33 114.3 36.3 5.7e-33 113.9 25.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ARL6IP6 PF15062.1 KHN69998.1 - 0.88 9.5 3.5 0.98 9.3 0.4 2.6 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix zf-ZPR1 PF03367.8 KHN69999.1 - 3.2e-07 29.6 5.7 6.7e-07 28.5 3.9 1.5 1 1 0 1 1 1 1 ZPR1 zinc-finger domain Elf1 PF05129.8 KHN69999.1 - 0.52 10.0 7.2 2.1 8.1 2.4 2.4 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like LisH PF08513.6 KHN70000.1 - 1.4e-09 37.3 0.2 3.2e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 LisH RCC1 PF00415.13 KHN70001.1 - 9.1e-53 176.2 3.4 4.8e-09 36.2 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KHN70001.1 - 2.6e-25 87.3 30.3 3e-06 26.6 0.1 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat tRNA_bind PF01588.15 KHN70002.1 - 1e-18 66.9 0.0 2e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain RabGAP-TBC PF00566.13 KHN70004.1 - 6.9e-32 110.6 2.5 9.9e-32 110.1 1.7 1.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FTR1 PF03239.9 KHN70005.1 - 0.034 13.0 0.1 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family mRNA_triPase PF02940.10 KHN70006.1 - 2.8e-28 99.1 7.5 1.2e-26 93.7 5.2 2.0 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Ras PF00071.17 KHN70007.1 - 1.8e-42 144.4 0.1 2.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN70007.1 - 1.5e-16 60.9 0.0 2.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN70007.1 - 1.6e-10 40.5 0.0 2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN70007.1 - 1.1e-08 34.5 0.0 1.3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KHN70007.1 - 4.4e-07 29.8 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KHN70007.1 - 6e-05 22.5 0.1 0.00056 19.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KHN70007.1 - 0.00032 20.3 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein DUF258 PF03193.11 KHN70007.1 - 0.062 12.4 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 KHN70007.1 - 0.083 12.6 0.1 0.48 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KHN70007.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA helicase FeoB_N PF02421.13 KHN70007.1 - 0.13 11.5 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF333 PF03891.10 KHN70008.1 - 0.072 12.9 2.5 7 6.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF333) SH3BGR PF04908.10 KHN70008.1 - 0.17 11.8 0.4 0.29 11.0 0.1 1.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Spore-coat_CotZ PF10612.4 KHN70009.1 - 0.01 15.7 0.1 0.081 12.8 0.0 2.0 2 0 0 2 2 2 0 Spore coat protein Z WD40 PF00400.27 KHN70009.1 - 0.021 14.6 3.5 1.5 8.8 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Sp100 PF03172.8 KHN70010.1 - 0.014 15.3 0.3 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 Sp100 domain TBPIP PF07106.8 KHN70011.1 - 0.0032 17.0 2.8 0.0037 16.8 1.9 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TBCA PF02970.11 KHN70011.1 - 0.0041 17.1 2.1 0.0047 16.9 1.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Suppressor_APC PF11414.3 KHN70011.1 - 0.02 14.6 0.3 0.035 13.8 0.2 1.4 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein SPATA24 PF15175.1 KHN70011.1 - 0.045 13.4 2.6 0.058 13.0 1.8 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Syntaxin PF00804.20 KHN70011.1 - 0.05 13.7 2.0 0.06 13.5 1.2 1.3 1 1 0 1 1 1 0 Syntaxin DUF2098 PF09871.4 KHN70011.1 - 0.058 13.3 1.5 0.06 13.2 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Tropomyosin_1 PF12718.2 KHN70011.1 - 0.074 12.9 4.1 0.11 12.2 2.8 1.4 1 1 0 1 1 1 0 Tropomyosin like ATP-synt_B PF00430.13 KHN70011.1 - 0.21 11.3 3.8 0.25 11.1 2.6 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Prefoldin_2 PF01920.15 KHN70011.1 - 1.1 9.0 6.1 3.4 7.4 2.1 2.0 1 1 1 2 2 2 0 Prefoldin subunit MIF4G PF02854.14 KHN70012.1 - 4.4e-18 65.4 6.2 1.2e-17 63.9 4.3 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KHN70012.1 - 0.67 9.6 5.3 0.85 9.3 0.1 3.3 3 1 1 4 4 4 0 MA3 domain CLTH PF10607.4 KHN70013.1 - 0.0055 16.4 0.3 0.013 15.1 0.1 1.8 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF2220 PF09983.4 KHN70013.1 - 0.047 12.8 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Cir_N PF10197.4 KHN70014.1 - 0.01 15.8 10.1 0.067 13.2 7.0 2.0 1 1 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR V-ATPase_G PF03179.10 KHN70014.1 - 0.042 14.1 5.5 0.046 14.0 3.8 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KHN70014.1 - 0.043 13.6 3.0 0.048 13.4 2.1 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Caldesmon PF02029.10 KHN70014.1 - 0.09 11.1 7.6 0.098 11.0 5.2 1.0 1 0 0 1 1 1 0 Caldesmon DUF2724 PF10893.3 KHN70014.1 - 0.12 12.2 1.5 0.2 11.5 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2724) Atrophin-1 PF03154.10 KHN70014.1 - 5.9 4.8 7.9 6.2 4.8 5.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF1229 PF06797.6 KHN70015.1 - 0.31 9.8 2.5 0.59 8.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Chs3p PF12271.3 KHN70016.1 - 9.2e-21 74.0 19.8 1.5e-20 73.3 13.7 1.2 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ABC_tran PF00005.22 KHN70017.1 - 2e-29 102.6 0.0 4.3e-29 101.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 KHN70017.1 - 9.1e-16 58.0 5.9 1.3e-15 57.5 4.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KHN70017.1 - 4.3e-07 29.3 2.0 5.1e-05 22.6 1.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KHN70017.1 - 5.4e-07 29.8 4.1 0.002 18.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KHN70017.1 - 6.5e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KHN70017.1 - 0.00011 21.6 0.0 0.00029 20.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KHN70017.1 - 0.00016 20.9 0.0 0.00033 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KHN70017.1 - 0.00051 19.7 0.1 0.0072 16.0 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_23 PF13476.1 KHN70017.1 - 0.0022 18.3 0.1 0.006 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 KHN70017.1 - 0.0046 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KHN70017.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KHN70017.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KHN70017.1 - 0.011 16.5 0.5 0.31 11.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KHN70017.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KHN70017.1 - 0.012 15.7 0.1 0.13 12.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KHN70017.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KHN70017.1 - 0.019 14.3 0.0 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 KHN70017.1 - 0.023 13.4 0.1 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 KHN70017.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KHN70017.1 - 0.085 12.7 1.0 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KHN70017.1 - 0.09 12.9 0.1 0.63 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 KHN70017.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KHN70017.1 - 0.15 12.3 1.1 3.3 8.0 0.2 3.2 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KHN70017.1 - 0.23 11.0 0.0 0.99 8.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3397 PF11877.3 KHN70017.1 - 2.5 8.0 7.9 3 7.8 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3397) Ribosomal_L31e PF01198.14 KHN70018.1 - 1e-16 60.3 0.7 1.3e-16 59.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DUF1132 PF06575.7 KHN70018.1 - 0.093 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Cpn60_TCP1 PF00118.19 KHN70019.1 - 2.3e-140 468.4 11.3 2.6e-140 468.2 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2837 PF10997.3 KHN70019.1 - 0.16 11.0 1.7 0.57 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2837) PSP1 PF04468.7 KHN70020.1 - 5.5e-31 106.4 0.7 5.5e-31 106.4 0.5 1.9 2 1 0 2 2 2 1 PSP1 C-terminal conserved region TatD_DNase PF01026.16 KHN70021.1 - 2.8e-49 167.6 0.0 3.4e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CENP-C_C PF11699.3 KHN70022.1 - 4.5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KHN70022.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain DUF3584 PF12128.3 KHN70022.1 - 0.064 10.5 3.4 0.025 11.9 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Mif2_N PF15624.1 KHN70022.1 - 0.31 11.6 2.9 0.38 11.3 0.3 2.1 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Chromo PF00385.19 KHN70023.1 - 2.2e-17 62.4 1.3 3.1e-16 58.7 0.5 2.5 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KHN70023.1 - 3e-08 33.3 0.2 4.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain Phage_lysozyme PF00959.14 KHN70023.1 - 0.016 15.4 1.6 0.044 14.0 0.1 2.2 1 1 0 2 2 2 0 Phage lysozyme Folliculin PF11704.3 KHN70023.1 - 0.73 9.3 0.0 0.73 9.3 0.0 2.5 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CDC45 PF02724.9 KHN70023.1 - 2.7 5.9 10.8 3.2 5.6 7.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.12 KHN70023.1 - 6.4 5.4 13.1 16 4.1 9.0 1.6 1 1 1 2 2 2 0 Presenilin Neur_chan_memb PF02932.11 KHN70023.1 - 8.2 6.2 6.4 10 5.9 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.7 KHN70023.1 - 9.6 4.8 7.6 12 4.4 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mg_trans_NIPA PF05653.9 KHN70024.1 - 1.5e-32 112.8 20.7 2.1e-23 82.7 4.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KHN70024.1 - 0.002 18.3 3.2 0.002 18.3 2.2 3.4 2 2 1 3 3 3 1 Multidrug resistance efflux transporter DUF4234 PF14018.1 KHN70024.1 - 0.015 15.0 11.4 0.52 10.0 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) SAYSvFN PF10260.4 KHN70024.1 - 0.039 13.7 2.1 6.2 6.6 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) PufQ PF05398.6 KHN70024.1 - 1.9 8.5 6.6 15 5.7 0.2 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit Fez1 PF06818.10 KHN70025.1 - 0.0028 17.7 12.9 0.0039 17.2 8.9 1.2 1 0 0 1 1 1 1 Fez1 DUF904 PF06005.7 KHN70025.1 - 0.0064 16.7 1.3 0.0064 16.7 0.9 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF904) FTA4 PF13093.1 KHN70025.1 - 0.012 15.0 9.0 0.02 14.3 6.3 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Syntaxin_2 PF14523.1 KHN70025.1 - 0.093 12.7 8.2 0.052 13.5 2.4 2.2 1 1 1 2 2 2 0 Syntaxin-like protein ABC1 PF03109.11 KHN70025.1 - 0.095 12.6 0.7 0.25 11.2 0.3 1.9 1 1 0 1 1 1 0 ABC1 family NPV_P10 PF05531.7 KHN70025.1 - 0.13 12.5 2.6 0.18 12.0 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 KHN70025.1 - 0.15 11.7 10.8 0.03 13.9 2.3 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 GlnE PF03710.10 KHN70025.1 - 0.56 9.4 6.7 1.8 7.7 0.9 2.5 2 1 1 3 3 3 0 Glutamate-ammonia ligase adenylyltransferase Reo_sigmaC PF04582.7 KHN70025.1 - 1.3 8.1 4.9 2.2 7.3 1.6 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Ead_Ea22 PF13935.1 KHN70025.1 - 2.1 8.7 10.3 5.3 7.3 6.6 1.9 1 1 1 2 2 2 0 Ead/Ea22-like protein Phage_GP20 PF06810.6 KHN70025.1 - 3 7.2 11.5 9.4 5.6 4.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 IncA PF04156.9 KHN70025.1 - 3 7.3 17.6 5.3 6.6 12.2 1.4 1 0 0 1 1 1 0 IncA protein DUF2203 PF09969.4 KHN70025.1 - 3 8.0 9.4 1.2 9.3 1.0 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 KHN70025.1 - 3.5 7.4 9.6 2.3 8.0 2.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec62 PF03839.11 KHN70025.1 - 3.7 6.8 6.8 0.66 9.3 0.7 2.0 1 1 1 2 2 2 0 Translocation protein Sec62 PspB PF06667.7 KHN70025.1 - 6.1 6.8 10.0 0.62 10.0 0.9 2.6 2 1 1 3 3 3 0 Phage shock protein B DUF2630 PF10944.3 KHN70025.1 - 9.5 6.4 11.2 5.3 7.2 1.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) TPT PF03151.11 KHN70026.1 - 1.1e-07 31.6 15.4 1.1e-07 31.6 10.7 2.7 1 1 1 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KHN70026.1 - 4.5e-07 29.9 25.2 2.5e-06 27.5 5.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KHN70026.1 - 0.00033 19.8 2.2 0.00033 19.8 1.6 2.7 2 2 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KHN70026.1 - 0.042 12.7 25.1 1 8.2 17.4 2.3 1 1 0 1 1 1 0 UAA transporter family Chs3p PF12271.3 KHN70027.1 - 0.0023 16.9 2.5 0.0033 16.4 1.8 1.2 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Prefoldin_3 PF13758.1 KHN70027.1 - 0.047 13.4 0.2 0.082 12.6 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit GWT1 PF06423.7 KHN70027.1 - 0.24 11.5 2.0 0.59 10.2 0.1 2.1 1 1 1 2 2 2 0 GWT1 YEATS PF03366.11 KHN70028.1 - 1.3e-18 66.4 0.3 2e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 YEATS family Ank_2 PF12796.2 KHN70029.1 - 6.2e-10 39.2 0.1 6.7e-09 35.9 0.0 2.5 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KHN70029.1 - 2.3e-09 37.4 0.4 2.6e-07 30.9 0.2 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KHN70029.1 - 4e-06 26.9 1.9 3.8e-05 23.7 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 KHN70029.1 - 0.0001 21.9 4.3 0.001 18.7 0.1 3.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.1 KHN70029.1 - 0.0025 17.9 3.9 0.045 13.9 0.1 4.4 5 0 0 5 5 5 1 Ankyrin repeat DUF2089 PF09862.4 KHN70029.1 - 0.12 12.1 0.2 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) Nup54 PF13874.1 KHN70030.1 - 0.0036 16.9 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 EF-hand_6 PF13405.1 KHN70031.1 - 2.7e-07 29.8 3.2 0.0023 17.6 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 KHN70031.1 - 1.4e-06 28.3 2.1 8e-05 22.7 1.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KHN70031.1 - 2.7e-05 23.1 7.4 0.0058 15.8 0.2 3.0 4 0 0 4 4 4 2 EF hand DnaB_2 PF07261.6 KHN70031.1 - 0.011 15.3 0.1 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Replication initiation and membrane attachment EF-hand_8 PF13833.1 KHN70031.1 - 0.085 12.4 3.2 2.1 8.0 0.3 2.9 3 1 0 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.1 KHN70031.1 - 1.7 8.1 7.7 5.8 6.4 0.6 2.5 2 0 0 2 2 2 0 EF hand Ras PF00071.17 KHN70032.1 - 9.4e-40 135.6 0.0 1.1e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN70032.1 - 2.8e-19 69.7 0.0 4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KHN70032.1 - 9.8e-07 28.3 0.0 2.2e-06 27.2 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN70032.1 - 3.5e-06 26.9 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KHN70032.1 - 0.0015 17.7 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 KHN70032.1 - 0.011 15.9 0.0 0.25 11.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF3579 PF12112.3 KHN70032.1 - 0.17 11.8 0.3 1.2 9.0 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3579) zf-RING_2 PF13639.1 KHN70033.1 - 3.7e-10 39.4 7.0 6.1e-10 38.7 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KHN70033.1 - 6.5e-06 25.7 6.9 6.5e-06 25.7 4.8 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KHN70033.1 - 1e-05 25.4 8.4 1.9e-05 24.5 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN70033.1 - 3.7e-05 23.2 4.9 6.1e-05 22.6 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KHN70033.1 - 7.2e-05 22.3 6.4 0.00014 21.4 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KHN70033.1 - 0.00017 21.5 6.1 0.00043 20.3 4.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KHN70033.1 - 0.042 13.7 6.1 0.12 12.2 4.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SYF2 PF08231.7 KHN70033.1 - 0.044 13.9 0.3 0.063 13.4 0.2 1.2 1 0 0 1 1 1 0 SYF2 splicing factor zf-Apc11 PF12861.2 KHN70033.1 - 0.063 13.1 5.4 0.22 11.3 3.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KHN70033.1 - 0.28 11.1 8.8 4.5 7.3 6.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KHN70033.1 - 0.39 10.4 5.0 0.78 9.5 3.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.16 KHN70033.1 - 0.67 9.8 6.2 3.5 7.6 4.3 2.0 1 1 0 1 1 1 0 FYVE zinc finger Prok-RING_1 PF14446.1 KHN70033.1 - 1 9.1 6.7 0.35 10.6 1.7 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 KHN70033.1 - 2.1 8.4 7.5 4.5 7.4 5.2 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KHN70033.1 - 3.6 7.3 8.2 8.9 6.0 5.7 1.7 1 1 0 1 1 1 0 PHD-finger SNF2_N PF00176.18 KHN70034.1 - 4.8e-53 179.8 0.0 7.8e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KHN70034.1 - 8e-15 54.4 0.1 2.1e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KHN70034.1 - 1.5e-05 24.6 0.0 3.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HEAT_2 PF13646.1 KHN70034.1 - 0.00011 22.4 0.0 0.061 13.6 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats WD40 PF00400.27 KHN70035.1 - 1.1e-23 82.1 5.6 3.1e-08 33.1 0.1 5.0 5 1 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KHN70035.1 - 0.071 11.3 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain CBFB_NFYA PF02045.10 KHN70036.1 - 1.7e-21 76.4 0.8 1.7e-21 76.4 0.5 1.5 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DnaJ PF00226.26 KHN70038.1 - 7.6e-11 41.5 0.5 1.1e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L18e PF00828.14 KHN70039.1 - 1.8e-09 38.0 1.1 3.1e-09 37.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DUF211 PF02680.9 KHN70039.1 - 0.0056 16.4 0.5 0.0093 15.7 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized ArCR, COG1888 EAP30 PF04157.11 KHN70039.1 - 0.067 12.3 0.0 0.18 10.9 0.0 1.7 1 1 0 1 1 1 0 EAP30/Vps36 family Histone PF00125.19 KHN70042.1 - 5e-23 81.0 0.1 7.8e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KHN70042.1 - 9.3e-05 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KHN70042.1 - 0.0053 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 KHN70042.1 - 0.0068 15.7 0.8 0.0079 15.4 0.5 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T PH_2 PF08458.5 KHN70042.1 - 0.0075 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Plant pleckstrin homology-like region CBFD_NFYB_HMF PF00808.18 KHN70042.1 - 0.0089 16.0 0.9 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SPATA25 PF15218.1 KHN70042.1 - 0.024 14.0 0.0 0.028 13.8 0.0 1.0 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 PolyA_pol PF01743.15 KHN70044.1 - 5.1e-25 88.1 0.0 2.1e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KHN70044.1 - 0.00013 21.5 0.0 0.00049 19.6 0.1 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Ras PF00071.17 KHN70045.1 - 5.2e-50 168.9 2.4 6.2e-50 168.7 1.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN70045.1 - 5.6e-20 72.0 0.3 8.3e-20 71.4 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN70045.1 - 3.4e-19 68.7 0.6 4.5e-19 68.3 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN70045.1 - 1e-11 44.4 1.0 1.3e-11 44.1 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KHN70045.1 - 6.5e-07 28.9 1.6 3.4e-06 26.6 1.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KHN70045.1 - 2e-06 27.1 0.1 2.6e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KHN70045.1 - 6e-06 26.1 0.4 1e-05 25.4 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KHN70045.1 - 1.3e-05 25.3 0.1 2.5e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KHN70045.1 - 0.00027 21.1 0.2 0.002 18.3 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 KHN70045.1 - 0.00056 19.4 0.3 0.0034 16.8 0.0 2.0 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 KHN70045.1 - 0.001 18.9 0.4 0.0028 17.5 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 KHN70045.1 - 0.0011 19.7 0.3 0.0033 18.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 KHN70045.1 - 0.0057 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_5 PF07728.9 KHN70045.1 - 0.0059 16.3 0.0 0.042 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KHN70045.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 KHN70045.1 - 0.011 14.7 6.3 0.014 14.4 4.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 KHN70045.1 - 0.023 13.9 0.1 0.048 12.9 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KHN70045.1 - 0.037 13.7 1.0 0.07 12.8 0.7 1.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 KHN70045.1 - 0.039 13.8 0.0 0.052 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KHN70045.1 - 0.043 13.4 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 KHN70045.1 - 0.045 14.0 0.3 0.11 12.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KHN70045.1 - 0.052 13.7 0.3 0.29 11.3 0.1 2.3 1 1 0 1 1 1 0 RNA helicase G-alpha PF00503.15 KHN70045.1 - 0.067 11.8 3.2 1 8.0 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.1 KHN70045.1 - 0.077 12.5 1.5 0.28 10.7 0.1 2.1 1 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KHN70045.1 - 0.095 12.1 0.1 0.17 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 KHN70045.1 - 0.12 12.6 0.3 0.22 11.7 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Pox_A32 PF04665.7 KHN70045.1 - 0.13 11.4 1.4 1.1 8.5 0.0 2.6 2 1 1 3 3 3 0 Poxvirus A32 protein AAA_16 PF13191.1 KHN70045.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain DUF4131 PF13567.1 KHN70046.1 - 2.4 7.5 6.1 4 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) AAA PF00004.24 KHN70047.1 - 4.4e-53 179.0 0.1 1.6e-38 131.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KHN70047.1 - 2.1e-11 44.0 5.0 0.00062 19.9 0.3 4.3 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KHN70047.1 - 6.1e-11 42.7 0.1 1.9e-05 24.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KHN70047.1 - 7.1e-09 35.8 0.0 0.00057 20.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.9 KHN70047.1 - 1e-08 35.0 0.0 0.00087 19.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KHN70047.1 - 1.1e-08 35.8 3.6 0.00056 20.7 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KHN70047.1 - 1.5e-08 34.6 0.3 0.00073 19.4 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KHN70047.1 - 3.8e-08 33.5 0.2 0.0043 17.0 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 KHN70047.1 - 6.6e-08 32.6 0.0 9.8e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KHN70047.1 - 2.4e-06 27.1 0.0 0.042 13.2 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KHN70047.1 - 7.9e-06 25.1 0.1 0.0028 16.8 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KHN70047.1 - 1.1e-05 25.0 1.9 0.12 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KHN70047.1 - 1.2e-05 24.8 3.9 0.2 11.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 KHN70047.1 - 3.5e-05 23.7 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KHN70047.1 - 4.1e-05 23.3 0.2 1.4 8.5 0.0 3.8 4 0 0 4 4 4 2 NACHT domain NB-ARC PF00931.17 KHN70047.1 - 4.3e-05 22.5 2.3 0.016 14.1 0.1 3.3 3 0 0 3 3 3 1 NB-ARC domain ABC_tran PF00005.22 KHN70047.1 - 7.9e-05 22.9 0.1 0.21 11.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_19 PF13245.1 KHN70047.1 - 0.00011 21.8 0.2 0.0093 15.7 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 KHN70047.1 - 0.00027 19.7 0.0 0.51 8.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus PhoH PF02562.11 KHN70047.1 - 0.00037 19.7 0.1 0.99 8.5 0.0 2.8 2 1 1 3 3 3 2 PhoH-like protein RuvB_N PF05496.7 KHN70047.1 - 0.00045 19.3 0.1 0.48 9.4 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 KHN70047.1 - 0.00052 19.5 0.1 0.38 10.2 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 KHN70047.1 - 0.0021 18.0 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KHN70047.1 - 0.0039 16.3 6.0 0.069 12.2 0.1 3.3 4 0 0 4 4 3 1 KaiC AAA_3 PF07726.6 KHN70047.1 - 0.0042 16.6 0.0 0.097 12.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KHN70047.1 - 0.0096 15.6 0.1 4.2 7.0 0.0 3.0 2 0 0 2 2 2 1 NTPase DUF258 PF03193.11 KHN70047.1 - 0.012 14.8 0.1 0.081 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 KHN70047.1 - 0.028 13.8 0.1 4.3 6.7 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 KHN70047.1 - 0.029 13.3 0.0 0.24 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.18 KHN70047.1 - 0.063 12.6 0.0 3.1 7.1 0.1 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 KHN70047.1 - 0.067 12.7 0.5 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 KHN70047.1 - 0.11 12.5 0.0 35 4.4 0.0 3.1 4 0 0 4 4 3 0 Sigma-54 interaction domain DEAD PF00270.24 KHN70047.1 - 0.11 11.9 1.2 38 3.7 0.0 3.5 2 2 0 3 3 3 0 DEAD/DEAH box helicase AAA_23 PF13476.1 KHN70047.1 - 4.8 7.4 11.4 8 6.7 0.1 3.6 2 1 0 3 3 3 0 AAA domain TPR_19 PF14559.1 KHN70048.1 - 1.5e-09 38.0 0.6 3.7e-06 27.1 0.0 3.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KHN70048.1 - 9.9e-09 34.7 4.9 5.2e-06 26.0 0.0 3.7 2 1 2 4 4 4 2 TPR repeat Apc3 PF12895.2 KHN70048.1 - 2.5e-08 33.9 3.0 3.2e-05 23.9 0.1 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KHN70048.1 - 8.2e-07 28.4 3.4 0.14 12.1 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KHN70048.1 - 9.5e-07 29.3 0.0 0.00032 21.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KHN70048.1 - 0.0002 21.7 0.0 0.77 10.5 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KHN70048.1 - 0.00035 20.5 0.5 0.59 10.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KHN70048.1 - 0.011 15.3 9.7 0.67 9.6 0.7 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KHN70048.1 - 0.013 15.4 1.8 0.31 11.0 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KHN70048.1 - 0.016 14.9 5.7 8.5 6.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KHN70048.1 - 0.074 13.5 4.2 3 8.5 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat Homeobox PF00046.24 KHN70049.1 - 6.9e-14 51.2 3.4 8.8e-14 50.8 2.4 1.2 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KHN70049.1 - 0.00012 21.7 1.3 0.00023 20.8 0.8 1.6 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KHN70049.1 - 0.007 15.3 0.2 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Carb_kinase PF01256.12 KHN70050.1 - 5.8e-34 117.4 0.0 7e-32 110.6 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate kinase eRF1_1 PF03463.10 KHN70051.1 - 1.3e-25 89.4 1.6 2.3e-25 88.7 1.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KHN70051.1 - 4.1e-12 46.3 0.1 1.4e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 eRF1 domain 3 Hist_deacetyl PF00850.14 KHN70052.1 - 5.4e-79 265.7 0.0 7.1e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain UPF0160 PF03690.8 KHN70053.1 - 1.3e-78 264.6 0.0 1.4e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) AAA PF00004.24 KHN70055.1 - 4.6e-42 143.3 0.0 9.2e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KHN70055.1 - 9.4e-07 28.6 0.1 7.1e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KHN70055.1 - 1.7e-05 24.9 0.0 0.00085 19.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN70055.1 - 9.3e-05 23.2 0.1 0.00023 21.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KHN70055.1 - 0.0001 22.3 0.0 0.00053 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KHN70055.1 - 0.00044 19.2 0.0 0.00068 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 KHN70055.1 - 0.00068 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KHN70055.1 - 0.00069 19.3 0.2 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 KHN70055.1 - 0.0014 18.6 0.0 0.0044 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KHN70055.1 - 0.002 17.2 0.0 0.0044 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KHN70055.1 - 0.0033 17.3 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KHN70055.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KHN70055.1 - 0.01 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 KHN70055.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KHN70055.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KHN70055.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KHN70055.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KHN70055.1 - 0.015 14.4 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 KHN70055.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 KHN70055.1 - 0.023 14.1 0.1 0.35 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KHN70055.1 - 0.03 14.0 0.1 1.6 8.3 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase AAA_3 PF07726.6 KHN70055.1 - 0.034 13.7 0.0 0.093 12.3 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KHN70055.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 KHN70055.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KHN70055.1 - 0.067 12.0 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KHN70055.1 - 0.075 11.8 0.0 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.1 KHN70055.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 KHN70055.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2348 PF09807.4 KHN70056.1 - 0.00063 18.9 0.0 0.086 11.9 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) ThiF PF00899.16 KHN70057.1 - 2.6e-42 143.8 0.1 4.4e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KHN70057.1 - 1.3e-23 82.3 0.8 2.7e-23 81.3 0.6 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KHN70057.1 - 2.1e-06 28.0 0.1 6.2e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Saccharop_dh PF03435.13 KHN70057.1 - 0.00019 20.5 0.1 0.0088 15.0 0.1 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KHN70057.1 - 0.0042 17.1 0.2 0.66 10.0 0.0 2.4 1 1 1 2 2 2 2 Shikimate / quinate 5-dehydrogenase DUF2338 PF10100.4 KHN70057.1 - 0.036 12.4 0.1 0.19 10.0 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2338) Cytidylate_kin PF02224.13 KHN70059.1 - 3.2e-39 133.8 6.7 4.1e-39 133.5 4.6 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.1 KHN70059.1 - 2.3e-09 37.6 0.9 8.3e-09 35.8 0.6 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN70059.1 - 1.1e-08 35.9 0.7 1.2e-07 32.6 0.5 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KHN70059.1 - 1.9e-08 34.4 1.1 3.7e-08 33.4 0.8 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.1 KHN70059.1 - 0.0022 17.9 0.1 0.011 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KHN70059.1 - 0.059 13.2 1.6 0.28 11.0 0.9 2.4 1 1 0 1 1 1 0 Adenylate kinase SKI PF01202.17 KHN70059.1 - 5.3 6.8 6.4 18 5.1 0.7 2.7 2 1 1 3 3 3 0 Shikimate kinase EMP24_GP25L PF01105.19 KHN70060.1 - 1.1e-08 34.9 0.7 1.7e-08 34.3 0.5 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Acetate_kinase PF00871.12 KHN70060.1 - 0.023 13.2 0.4 0.029 12.8 0.3 1.0 1 0 0 1 1 1 0 Acetokinase family SoxZ PF08770.6 KHN70060.1 - 0.054 12.9 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ YfkD PF14167.1 KHN70060.1 - 0.057 12.4 0.1 0.075 12.0 0.1 1.1 1 0 0 1 1 1 0 YfkD-like protein GPI2 PF06432.6 KHN70061.1 - 1.2e-09 37.8 17.4 3.8e-09 36.2 12.1 1.7 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase ATP_bind_3 PF01171.15 KHN70062.1 - 9.3e-18 64.3 0.0 1.3e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 KHN70062.1 - 0.0002 20.0 0.2 0.00043 18.9 0.1 1.5 1 1 0 1 1 1 1 tRNA methyl transferase DUF208 PF02677.9 KHN70062.1 - 0.005 16.6 0.0 0.95 9.2 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized BCR, COG1636 PAPS_reduct PF01507.14 KHN70062.1 - 0.0061 16.3 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.9 KHN70062.1 - 0.0096 15.3 0.1 0.029 13.8 0.1 1.8 2 1 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 KHN70062.1 - 0.023 14.2 0.0 0.044 13.2 0.0 1.4 1 1 0 1 1 1 0 Asparagine synthase DUF2392 PF10288.4 KHN70062.1 - 0.025 14.8 0.0 0.066 13.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) NAD_synthase PF02540.12 KHN70062.1 - 0.048 12.5 0.1 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase MafB19-deam PF14437.1 KHN70062.1 - 0.052 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 MafB19-like deaminase DegS PF05384.6 KHN70062.1 - 0.11 11.7 0.2 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Sensor protein DegS PCP_red PF08369.5 KHN70062.1 - 0.16 11.8 0.2 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit DZR PF12773.2 KHN70062.1 - 1.6 8.5 8.1 5 7.0 0.4 3.2 3 0 0 3 3 3 0 Double zinc ribbon Ribosomal_L36 PF00444.13 KHN70062.1 - 7.1 6.7 9.0 5.2 7.1 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein L36 WD40 PF00400.27 KHN70063.1 - 2.4e-06 27.2 0.1 0.029 14.2 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.1 KHN70063.1 - 0.022 14.2 0.0 4 6.8 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Thiol-ester_cl PF10569.4 KHN70063.1 - 0.034 13.3 0.1 0.085 12.1 0.1 1.7 1 0 0 1 1 1 0 Alpha-macro-globulin thiol-ester bond-forming region Ribosomal_L3 PF00297.17 KHN70064.1 - 2.1e-85 286.3 12.2 2.5e-85 286.0 8.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Rep_1 PF01446.12 KHN70065.1 - 0.018 14.3 1.7 0.025 13.9 1.2 1.4 1 1 0 1 1 1 0 Replication protein DUF4313 PF14190.1 KHN70065.1 - 0.042 13.5 0.3 0.077 12.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) UMPH-1 PF05822.7 KHN70065.1 - 0.054 12.8 0.6 0.064 12.5 0.4 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DSPn PF14671.1 KHN70065.1 - 0.079 12.9 1.4 0.14 12.1 1.0 1.5 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PMM PF03332.8 KHN70065.1 - 0.091 12.3 1.3 0.1 12.1 0.9 1.1 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase TPR_6 PF13174.1 KHN70065.1 - 0.86 10.2 0.1 0.86 10.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AhpC-TSA PF00578.16 KHN70066.1 - 1.5e-25 89.2 0.0 2e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KHN70066.1 - 1.7e-09 37.3 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Peptidase_S8 PF00082.17 KHN70067.1 - 9.7e-27 93.8 1.1 1.3e-26 93.4 0.7 1.3 1 0 0 1 1 1 1 Subtilase family DUF3067 PF11267.3 KHN70067.1 - 0.093 12.8 0.1 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3067) Homeobox PF00046.24 KHN70069.1 - 4.3e-19 67.8 1.6 8.5e-19 66.9 1.1 1.5 1 0 0 1 1 1 1 Homeobox domain Syja_N PF02383.13 KHN70070.1 - 1.6e-49 168.4 0.9 3.6e-49 167.2 0.6 1.6 1 1 0 1 1 1 1 SacI homology domain Imm45 PF15603.1 KHN70070.1 - 0.059 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 45 CH PF00307.26 KHN70071.1 - 2.5e-07 30.7 0.2 3.3e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain AAA_25 PF13481.1 KHN70073.1 - 0.00013 21.4 0.2 0.0039 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain Stn1 PF10451.4 KHN70073.1 - 0.0007 18.5 0.2 0.001 17.9 0.2 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 KaiC PF06745.8 KHN70073.1 - 0.0036 16.4 4.1 0.13 11.4 2.8 2.3 1 1 0 1 1 1 1 KaiC AAA PF00004.24 KHN70073.1 - 0.0048 17.1 0.2 0.015 15.4 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KHN70073.1 - 0.024 14.7 0.8 0.054 13.6 0.5 1.6 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 KHN70074.1 - 3.5e-09 36.4 21.0 7.6e-07 28.9 3.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Rhomboid PF01694.17 KHN70074.1 - 0.63 10.0 8.4 0.7 9.9 5.4 1.4 1 1 0 1 1 1 0 Rhomboid family MatE PF01554.13 KHN70074.1 - 4.9 6.7 16.4 0.51 9.9 8.0 1.8 2 1 0 2 2 2 0 MatE NMT_C PF02799.10 KHN70076.1 - 1.4e-28 99.5 0.2 2.1e-28 99.0 0.1 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KHN70076.1 - 5.1e-24 84.7 0.0 8.3e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KHN70076.1 - 0.0013 18.6 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KHN70076.1 - 0.0024 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KHN70076.1 - 0.0025 17.8 0.1 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KHN70076.1 - 0.0075 16.2 0.1 0.065 13.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KHN70076.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KHN70076.1 - 0.028 14.5 1.0 0.086 13.0 0.1 2.4 3 1 1 4 4 4 0 Acetyltransferase (GNAT) domain PQQ_3 PF13570.1 KHN70077.1 - 2.5e-06 27.5 3.9 0.98 9.7 0.0 3.7 2 1 1 3 3 3 3 PQQ-like domain PI3_PI4_kinase PF00454.22 KHN70078.1 - 3.3e-28 98.7 0.2 7.7e-28 97.5 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase YuiB PF14068.1 KHN70079.1 - 0.048 13.9 0.5 0.21 11.9 0.1 2.2 2 0 0 2 2 2 0 Putative membrane protein XPG_I PF00867.13 KHN70080.1 - 5.2e-28 96.9 0.0 1.2e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KHN70080.1 - 1.1e-27 96.1 0.0 2.1e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KHN70080.1 - 4.8e-07 29.9 0.0 1.3e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 KHN70080.1 - 0.034 14.3 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.2 KHN70080.1 - 0.09 12.6 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TFIIA PF03153.8 KHN70081.1 - 3.6e-17 63.3 6.5 1.2e-15 58.2 0.7 2.0 1 1 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Far-17a_AIG1 PF04750.9 KHN70082.1 - 1.9e-24 85.9 9.9 2.2e-24 85.7 6.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Far-17a_AIG1 PF04750.9 KHN70083.1 - 1.7e-26 92.6 14.2 2.2e-26 92.2 9.8 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Fig1 PF12351.3 KHN70083.1 - 1.5 8.6 6.8 1.3 8.8 0.7 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Myb_DNA-binding PF00249.26 KHN70084.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain B PF02216.11 KHN70084.1 - 0.005 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 B domain Myb_DNA-bind_6 PF13921.1 KHN70084.1 - 0.046 13.8 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain AAA_22 PF13401.1 KHN70085.1 - 1e-10 41.8 0.0 1.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KHN70085.1 - 2.5e-07 30.9 0.1 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KHN70085.1 - 5.6e-07 29.7 0.0 1.8e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KHN70085.1 - 7.5e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KHN70085.1 - 0.00014 21.7 0.1 0.00041 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KHN70085.1 - 0.00029 21.6 0.1 0.00087 20.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KHN70085.1 - 0.0005 20.3 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KHN70085.1 - 0.00061 19.5 0.0 0.0051 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KHN70085.1 - 0.0016 17.9 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 KHN70085.1 - 0.0031 16.3 0.1 0.0056 15.5 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KHN70085.1 - 0.0033 17.1 1.1 0.019 14.6 0.1 2.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 KHN70085.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 KHN70085.1 - 0.015 14.2 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 KHN70085.1 - 0.016 13.9 0.0 0.046 12.4 0.0 1.7 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 KHN70085.1 - 0.022 14.2 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.24 KHN70085.1 - 0.023 14.1 0.1 0.42 10.0 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.1 KHN70085.1 - 0.03 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KHN70085.1 - 0.043 13.7 1.1 0.086 12.7 0.0 2.0 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) Kinesin PF00225.18 KHN70085.1 - 0.059 12.0 0.0 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Kinesin motor domain AAA_33 PF13671.1 KHN70085.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KHN70085.1 - 0.084 11.9 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Zot PF05707.7 KHN70085.1 - 0.12 11.7 0.3 0.59 9.5 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 KHN70085.1 - 0.22 10.4 3.6 0.57 9.0 1.4 2.2 2 1 0 2 2 2 0 PIF1-like helicase 14-3-3 PF00244.15 KHN70087.1 - 2.2e-86 288.8 6.1 2.5e-86 288.6 4.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF2096 PF09869.4 KHN70087.1 - 0.02 14.8 0.4 0.06 13.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) MS_channel PF00924.13 KHN70088.1 - 4.1e-11 42.5 3.5 8.5e-11 41.5 2.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel CAP PF00188.21 KHN70089.1 - 7.3e-12 45.8 0.4 2e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family FeoC PF09012.5 KHN70089.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator Pkinase PF00069.20 KHN70090.1 - 4.4e-68 229.2 0.0 6.4e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70090.1 - 7.6e-32 110.3 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN70090.1 - 4e-09 35.8 0.0 6.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KHN70090.1 - 4.2e-05 22.9 1.4 7.9e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KHN70090.1 - 5.7e-05 22.9 0.6 0.004 16.9 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KHN70090.1 - 0.00021 20.4 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family eIF3_N PF09440.5 KHN70091.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.1 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain Ribosomal_L30 PF00327.15 KHN70093.1 - 4.2e-15 55.0 0.6 7.6e-15 54.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF685 PF05085.7 KHN70093.1 - 0.0069 15.4 0.5 0.011 14.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF685) KilA-N PF04383.8 KHN70093.1 - 0.057 13.0 0.9 0.13 11.9 0.1 1.9 3 0 0 3 3 3 0 KilA-N domain zf-C2H2_4 PF13894.1 KHN70094.1 - 9.6e-06 25.5 5.4 0.097 13.0 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KHN70094.1 - 0.0001 22.4 10.9 0.021 15.1 0.3 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KHN70094.1 - 0.00077 19.6 0.5 0.00077 19.6 0.4 4.1 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KHN70094.1 - 0.018 15.1 3.4 0.7 10.1 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 KHN70094.1 - 0.16 12.1 1.7 13 6.0 0.6 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ThiF PF00899.16 KHN70095.1 - 3.9e-44 149.7 2.8 3.8e-27 94.7 0.6 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KHN70095.1 - 5.7e-33 112.3 2.9 1e-25 89.0 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KHN70095.1 - 1.7e-24 86.3 0.3 4.2e-24 85.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KHN70095.1 - 8.1e-20 69.9 2.0 1.6e-19 68.9 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site tRNA_int_endo PF01974.12 KHN70096.1 - 5.2e-14 51.8 0.0 6.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pkinase PF00069.20 KHN70097.1 - 8.8e-36 123.3 0.1 9.9e-36 123.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70097.1 - 1.9e-15 56.6 0.1 2.3e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KHN70097.1 - 0.00052 19.8 0.0 0.016 14.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KHN70097.1 - 0.021 13.7 0.1 0.043 12.7 0.1 1.5 1 1 0 1 1 1 0 Kinase-like L_protein_N PF15518.1 KHN70097.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 L protein N-terminus Choline_kinase PF01633.15 KHN70097.1 - 0.073 12.6 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 KHN70097.1 - 0.079 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec1 PF00995.18 KHN70098.1 - 2.3e-87 293.9 2.0 3.2e-87 293.5 1.4 1.2 1 0 0 1 1 1 1 Sec1 family DUF3635 PF12330.3 KHN70099.1 - 3e-11 43.2 0.1 1.1e-10 41.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase_Tyr PF07714.12 KHN70099.1 - 2.6e-05 23.4 0.1 0.00016 20.8 0.1 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 KHN70099.1 - 0.0001 21.9 0.2 0.0001 21.9 0.2 2.5 3 1 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.18 KHN70099.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3562 PF12085.3 KHN70100.1 - 0.00073 19.3 0.3 0.76 9.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3562) DHHW PF14286.1 KHN70100.1 - 0.032 13.5 0.8 0.046 13.0 0.6 1.2 1 0 0 1 1 1 0 DHHW protein ATP-cone PF03477.11 KHN70100.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.7 3 0 0 3 3 3 0 ATP cone domain Tim17 PF02466.14 KHN70102.1 - 0.082 12.9 1.5 0.11 12.5 1.1 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family LSM PF01423.17 KHN70104.1 - 2.3e-11 43.0 0.1 2.7e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KHN70104.1 - 0.0019 18.0 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 KHN70104.1 - 0.042 13.6 0.0 0.052 13.3 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain UcrQ PF02939.11 KHN70105.1 - 0.098 12.4 0.1 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 UcrQ family Tubulin PF00091.20 KHN70106.1 - 8.5e-71 238.2 0.0 1.3e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KHN70106.1 - 4e-47 159.3 0.2 6.2e-47 158.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KHN70106.1 - 9.5e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Sedlin_N PF04628.8 KHN70107.1 - 1.6e-10 40.9 0.7 1.9e-10 40.7 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Urm1 PF09138.6 KHN70108.1 - 2.8e-11 43.3 0.1 3.1e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KHN70108.1 - 0.039 14.3 0.0 0.059 13.7 0.0 1.4 1 1 0 1 1 1 0 ThiS family zf-C2H2 PF00096.21 KHN70109.1 - 1.4e-14 53.4 62.6 0.00029 21.0 1.4 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KHN70109.1 - 7.5e-13 47.8 52.5 0.0003 20.9 1.2 6.3 6 0 0 6 6 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KHN70109.1 - 1.1e-10 41.2 61.8 8.9e-06 25.7 1.4 6.5 5 1 1 6 6 6 5 Zinc-finger double domain zf-H2C2_5 PF13909.1 KHN70109.1 - 0.0032 17.5 2.6 0.0032 17.5 1.8 5.9 4 2 1 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 KHN70109.1 - 0.028 14.5 42.9 1 9.5 0.2 5.8 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KHN70109.1 - 0.03 14.5 29.3 0.69 10.2 2.3 5.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Membrane_bind PF14564.1 KHN70111.1 - 0.0035 17.5 0.1 0.0079 16.3 0.1 1.5 1 0 0 1 1 1 1 Membrane binding RRM_1 PF00076.17 KHN70112.1 - 3.7e-11 42.4 0.0 6.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70112.1 - 1.1e-10 41.1 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN70112.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN70113.1 - 8.1e-07 28.5 0.2 6.1e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN70113.1 - 1.2e-06 28.3 0.2 9.2e-05 22.3 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70113.1 - 1.1e-05 25.1 0.1 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN70114.1 - 5.1e-31 106.1 2.3 1.2e-14 53.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN70114.1 - 3.2e-25 87.9 0.2 1.2e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70114.1 - 2.2e-09 37.0 0.1 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KHN70114.1 - 0.0012 18.5 0.2 0.45 10.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.1 KHN70114.1 - 0.013 14.5 0.0 3.7 6.6 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4283) RRM_3 PF08777.6 KHN70114.1 - 0.025 14.4 2.6 1.2 9.0 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif Flexi_CP_N PF08358.5 KHN70114.1 - 0.099 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Carlavirus coat Daxx PF03344.10 KHN70114.1 - 0.22 9.9 8.3 0.34 9.3 5.7 1.3 1 0 0 1 1 1 0 Daxx Family Ribosomal_L34e PF01199.13 KHN70115.1 - 2.2e-27 95.1 7.2 2.6e-27 94.8 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Mut7-C PF01927.11 KHN70115.1 - 0.026 14.5 1.5 0.03 14.2 1.0 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain FYVE PF01363.16 KHN70115.1 - 0.12 12.2 1.7 0.25 11.2 1.2 1.5 1 1 0 1 1 1 0 FYVE zinc finger RNB PF00773.14 KHN70116.1 - 5e-87 292.2 0.0 6.9e-87 291.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 KHN70116.1 - 0.0036 16.7 1.3 0.0055 16.1 0.1 1.8 2 0 0 2 2 2 1 Ribonuclease B OB domain zf-Di19 PF05605.7 KHN70117.1 - 0.014 15.5 0.6 0.05 13.7 0.1 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PFK PF00365.15 KHN70118.1 - 1.1e-140 467.5 5.5 1.2e-92 309.8 0.4 2.2 2 0 0 2 2 2 2 Phosphofructokinase NAD_kinase PF01513.16 KHN70118.1 - 0.014 14.2 0.0 0.15 10.8 0.0 2.2 2 0 0 2 2 2 0 ATP-NAD kinase Lactamase_B_4 PF13691.1 KHN70118.1 - 0.021 14.3 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 tRNase Z endonuclease Mpp10 PF04006.7 KHN70118.1 - 1.7 6.9 5.8 2.3 6.4 4.0 1.1 1 0 0 1 1 1 0 Mpp10 protein RNase_HII PF01351.13 KHN70119.1 - 7.9e-40 136.6 0.0 9.6e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Hormone_recep PF00104.25 KHN70119.1 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor LRR_5 PF13306.1 KHN70119.1 - 0.018 14.7 0.4 0.03 14.0 0.3 1.3 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) UCH PF00443.24 KHN70120.1 - 1.2e-32 113.1 0.6 2.2e-32 112.2 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KHN70120.1 - 5.2e-17 61.7 4.0 5.2e-17 61.7 2.8 3.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KHN70120.1 - 1.1e-06 28.3 0.1 2.2e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S11 PF00411.14 KHN70121.1 - 9.6e-33 112.6 1.0 1.2e-32 112.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Rpr2 PF04032.11 KHN70122.1 - 2.2e-05 24.2 1.5 3.8e-05 23.4 1.1 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.16 KHN70122.1 - 0.065 13.1 3.3 0.16 11.9 2.3 1.8 1 1 0 1 1 1 0 FYVE zinc finger Cys_rich_KTR PF14205.1 KHN70122.1 - 0.27 10.7 3.1 0.23 10.9 0.4 2.0 2 0 0 2 2 2 0 Cysteine-rich KTR PHD PF00628.24 KHN70122.1 - 1.3 8.7 7.0 4.5 7.0 0.4 2.7 2 1 0 2 2 2 0 PHD-finger Pkinase PF00069.20 KHN70123.1 - 3.9e-37 127.8 0.0 5.9e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70123.1 - 8e-14 51.3 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KHN70123.1 - 0.035 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeobox PF00046.24 KHN70124.1 - 2.5e-12 46.2 0.7 4.2e-12 45.4 0.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KHN70124.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain Yip1 PF04893.12 KHN70125.1 - 4.4e-08 32.8 8.4 5.8e-08 32.4 5.8 1.2 1 0 0 1 1 1 1 Yip1 domain UCH PF00443.24 KHN70126.1 - 8.1e-42 143.1 2.6 1.3e-41 142.5 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KHN70126.1 - 1.7e-22 80.2 0.4 3.8e-22 79.0 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Vac_ImportDeg PF09783.4 KHN70127.1 - 4.9e-43 146.6 0.3 6.5e-43 146.2 0.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein RabGAP-TBC PF00566.13 KHN70128.1 - 4.9e-34 117.6 2.1 1.5e-33 116.1 1.4 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RhoGEF PF00621.15 KHN70129.1 - 1.2e-21 77.3 1.0 2.7e-21 76.2 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 KHN70129.1 - 3.7e-16 59.3 0.1 7.8e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 CNH domain MutS_V PF00488.16 KHN70130.1 - 5.8e-68 228.8 0.1 8.8e-68 228.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KHN70130.1 - 1.6e-22 80.2 0.2 2.6e-22 79.6 0.1 1.3 1 0 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 KHN70130.1 - 0.14 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Synaptobrevin PF00957.16 KHN70131.1 - 8.1e-09 34.9 0.1 1.8e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Lumazine_bd PF12870.2 KHN70131.1 - 0.00044 20.2 1.1 0.0011 18.9 0.1 2.1 2 1 0 2 2 2 1 Lumazine-binding domain Longin PF13774.1 KHN70131.1 - 0.0039 16.7 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec5 PF15469.1 KHN70131.1 - 0.021 14.5 0.2 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 GED PF02212.13 KHN70131.1 - 0.18 11.7 1.8 0.2 11.5 0.4 1.7 2 1 0 2 2 2 0 Dynamin GTPase effector domain HSP70 PF00012.15 KHN70132.1 - 1.4e-173 578.0 8.0 2.6e-98 329.5 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 KHN70132.1 - 2.7e-11 42.6 0.0 9.7e-05 21.1 0.0 3.6 3 0 0 3 3 3 3 MreB/Mbl protein FGGY_C PF02782.11 KHN70132.1 - 6.8e-06 25.8 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 KHN70132.1 - 0.0002 20.5 0.6 0.43 9.6 0.0 2.8 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DUF1539 PF07560.6 KHN70132.1 - 0.01 15.7 0.4 0.023 14.5 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) V-ATPase_C PF03223.10 KHN70134.1 - 3.9e-50 170.8 0.5 4.5e-50 170.6 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2179 PF10035.4 KHN70134.1 - 0.099 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2179) TFIIS_C PF01096.13 KHN70135.1 - 5.9e-18 64.2 4.7 5.9e-18 64.2 3.3 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.3 KHN70135.1 - 0.011 15.1 1.9 0.011 15.1 1.3 2.8 2 1 1 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain C1_3 PF07649.7 KHN70135.1 - 0.33 11.0 0.2 0.33 11.0 0.1 2.9 4 0 0 4 4 4 0 C1-like domain Metallothio_2 PF01439.13 KHN70135.1 - 1.6 9.3 9.4 0.12 12.9 1.9 2.1 1 1 1 2 2 2 0 Metallothionein zf-met PF12874.2 KHN70136.1 - 5.4e-05 23.2 1.5 0.00011 22.2 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KHN70136.1 - 0.0045 17.0 1.2 0.011 15.8 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding CactinC_cactus PF09732.4 KHN70136.1 - 0.042 13.4 0.8 0.076 12.6 0.5 1.3 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein zf-Sec23_Sec24 PF04810.10 KHN70136.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Arf PF00025.16 KHN70137.1 - 2.2e-34 118.1 0.0 2.8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KHN70137.1 - 4.2e-14 52.2 0.0 6.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN70137.1 - 2.7e-10 40.7 0.0 3.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KHN70137.1 - 3.4e-08 32.9 0.0 4.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KHN70137.1 - 7.5e-08 32.3 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KHN70137.1 - 3.3e-06 26.0 1.9 0.0053 15.4 0.5 2.9 2 1 0 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 KHN70137.1 - 9.2e-06 25.2 0.0 0.00013 21.5 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KHN70137.1 - 1.5e-05 24.3 0.0 1.9e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KHN70137.1 - 0.07 12.4 0.0 1.6 7.9 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B SIR2 PF02146.12 KHN70138.1 - 5.3e-31 107.7 0.1 7.5e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family APP_amyloid PF10515.4 KHN70138.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 beta-amyloid precursor protein C-terminus DUF1764 PF08576.5 KHN70139.1 - 3.6e-18 66.2 4.5 4.2e-18 66.0 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) RNA_pol_Rpb2_6 PF00562.23 KHN70140.1 - 2.4e-102 342.5 0.9 4.7e-72 242.8 0.1 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KHN70140.1 - 5.7e-24 84.1 0.1 8.8e-24 83.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KHN70140.1 - 1.5e-21 75.8 0.0 3.4e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 KHN70140.1 - 1.8e-21 76.1 0.1 4.9e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 KHN70140.1 - 6.7e-17 61.5 0.2 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KHN70140.1 - 0.02 14.6 0.4 0.12 12.2 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 Chitin_bind_4 PF00379.18 KHN70140.1 - 0.026 14.8 1.0 0.064 13.5 0.7 1.7 1 0 0 1 1 1 0 Insect cuticle protein WD40 PF00400.27 KHN70141.1 - 6.2e-45 149.5 15.1 1.5e-07 31.0 0.1 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 KHN70141.1 - 5e-05 23.0 1.7 0.01 15.6 0.0 4.0 1 1 3 5 5 5 1 Ciliary BBSome complex subunit 2, middle region NLE PF08154.7 KHN70141.1 - 0.0022 17.9 0.2 0.0079 16.1 0.1 1.9 1 1 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KHN70141.1 - 0.01 14.0 0.2 0.073 11.1 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Kelch_4 PF13418.1 KHN70141.1 - 0.31 10.8 2.1 15 5.4 0.2 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain SPT16 PF08644.6 KHN70142.1 - 3.1e-25 88.7 0.1 7.2e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KHN70142.1 - 4.1e-10 39.4 0.0 2.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 KHN70142.1 - 4.6e-10 39.3 1.0 4.6e-10 39.3 0.7 3.2 4 1 1 5 5 5 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 KHN70142.1 - 4.5e-08 32.9 0.0 8.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 TraH_2 PF06871.6 KHN70142.1 - 0.034 13.5 2.2 0.066 12.6 1.5 1.4 1 0 0 1 1 1 0 TraH_2 DUF3326 PF11805.3 KHN70142.1 - 0.15 10.7 0.2 0.29 9.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) CDC45 PF02724.9 KHN70142.1 - 0.98 7.3 10.8 1.5 6.7 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Cyclin_N PF00134.18 KHN70143.1 - 0.00068 19.2 1.7 0.012 15.1 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain CLAMP PF14769.1 KHN70143.1 - 0.083 13.0 1.1 0.28 11.3 0.8 2.0 1 1 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 ARA70 PF12489.3 KHN70144.1 - 0.06 13.3 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Nuclear coactivator ABC2_membrane PF01061.19 KHN70145.1 - 1.2e-42 145.4 25.9 1.2e-42 145.4 18.0 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KHN70145.1 - 7e-26 91.1 0.0 1.1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 KHN70145.1 - 4.7e-07 29.1 18.8 4.7e-07 29.1 13.0 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 KHN70145.1 - 2.1e-06 27.9 4.2 0.011 15.7 0.0 3.0 2 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KHN70145.1 - 0.0003 20.0 0.1 0.001 18.3 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KHN70145.1 - 0.00096 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KHN70145.1 - 0.0033 16.9 0.1 0.0072 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KHN70145.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KHN70145.1 - 0.0043 17.8 0.0 0.0086 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KHN70145.1 - 0.012 15.7 0.1 0.035 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KHN70145.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DnaB PF00772.16 KHN70145.1 - 0.028 14.2 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase N terminal domain cobW PF02492.14 KHN70145.1 - 0.042 13.3 0.2 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.11 KHN70145.1 - 0.055 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 KHN70145.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KHN70145.1 - 0.1 12.0 0.4 0.21 11.0 0.3 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KHN70145.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KHN70145.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KHN70145.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KHN70145.1 - 0.22 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KHN70145.1 - 0.45 10.4 1.7 3.8 7.4 0.1 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_2 PF12679.2 KHN70145.1 - 0.7 8.6 16.0 0.11 11.2 8.3 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein SPC12 PF06645.8 KHN70147.1 - 1.6e-19 69.5 0.6 1.7e-19 69.3 0.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) PUCC PF03209.10 KHN70147.1 - 0.0014 17.4 0.2 0.0014 17.4 0.1 1.0 1 0 0 1 1 1 1 PUCC protein SdpI PF13630.1 KHN70147.1 - 0.0094 15.6 2.3 0.011 15.4 1.6 1.1 1 0 0 1 1 1 1 SdpI/YhfL protein family DUF3487 PF11990.3 KHN70147.1 - 0.029 13.7 0.6 0.032 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF4064 PF13273.1 KHN70147.1 - 0.037 14.1 3.7 0.041 13.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Glycoprotein_B PF00606.13 KHN70147.1 - 0.13 10.2 0.9 0.13 10.2 0.6 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF21 PF01595.15 KHN70147.1 - 0.15 11.2 0.9 0.2 10.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF21 DUF2013 PF09431.5 KHN70147.1 - 0.16 11.7 0.9 0.19 11.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) DUF4191 PF13829.1 KHN70147.1 - 0.17 11.0 2.4 0.18 10.8 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) ZYG-11_interact PF05884.7 KHN70147.1 - 0.17 10.9 1.5 0.18 10.8 1.0 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 LSM PF01423.17 KHN70149.1 - 6.6e-11 41.6 0.3 7.7e-11 41.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain TBCC PF07986.7 KHN70149.1 - 0.12 11.8 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C DUF4451 PF14616.1 KHN70150.1 - 2.1e-22 79.1 8.1 3.3e-21 75.3 5.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zf-DBF PF07535.7 KHN70150.1 - 0.055 13.1 0.6 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 DBF zinc finger Ecl1 PF12855.2 KHN70150.1 - 0.059 12.6 0.2 0.61 9.4 0.0 2.3 2 0 0 2 2 2 0 Life-span regulatory factor zf-U1 PF06220.7 KHN70150.1 - 0.096 12.2 1.1 2.8 7.5 0.4 2.7 2 0 0 2 2 2 0 U1 zinc finger zf-met PF12874.2 KHN70150.1 - 0.76 10.0 4.7 8.2 6.7 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KHN70150.1 - 1.5 9.0 8.5 5.9 7.1 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PIP5K PF01504.13 KHN70151.1 - 9.7e-52 175.5 0.4 1.1e-51 175.3 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ribosomal_L13e PF01294.13 KHN70152.1 - 7.9e-33 113.4 0.6 9.1e-33 113.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e Hom_end PF05204.9 KHN70152.1 - 0.094 12.6 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 Homing endonuclease Ribosomal_S9 PF00380.14 KHN70153.1 - 3.4e-23 82.1 0.0 3.9e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ATP-synt_F PF01990.12 KHN70154.1 - 5.5e-21 74.7 0.1 6.1e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit KaiC PF06745.8 KHN70154.1 - 0.05 12.7 0.0 0.054 12.6 0.0 1.1 1 0 0 1 1 1 0 KaiC RabGGT_insert PF07711.6 KHN70154.1 - 0.091 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain Skp1 PF01466.14 KHN70155.1 - 1e-18 67.1 0.0 1.8e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KHN70155.1 - 0.0028 17.6 0.1 0.0057 16.7 0.1 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain RNA_pol_Rpb1_1 PF04997.7 KHN70156.1 - 2.5e-108 362.3 0.0 6.4e-108 360.9 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KHN70156.1 - 9.5e-88 294.0 0.0 2.3e-87 292.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KHN70156.1 - 1.6e-68 229.8 0.2 4e-68 228.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KHN70156.1 - 3.6e-49 166.5 0.3 2.1e-48 164.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KHN70156.1 - 5e-37 125.9 1.0 1.3e-36 124.6 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_6 PF04992.9 KHN70156.1 - 2e-30 105.9 2.5 1.8e-29 102.8 1.7 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 KHN70156.1 - 4.9e-29 100.7 1.1 9.1e-29 99.8 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.8 KHN70156.1 - 1e-16 59.4 112.6 0.014 15.4 7.5 8.0 1 1 7 10 10 10 10 RNA polymerase Rpb1 C-terminal repeat UDPGP PF01704.13 KHN70157.1 - 1.2e-150 501.6 0.7 1.5e-150 501.4 0.5 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Adaptin_N PF01602.15 KHN70158.1 - 9.6e-33 113.2 10.8 9.2e-24 83.6 0.9 2.8 2 1 1 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.1 KHN70158.1 - 4e-08 33.4 0.9 0.058 13.6 0.1 5.2 3 2 3 6 6 6 3 HEAT repeats COP-gamma_platf PF08752.5 KHN70158.1 - 1.4e-07 31.4 3.8 2.4e-07 30.7 1.2 2.2 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT PF02985.17 KHN70158.1 - 0.0029 17.5 1.5 0.59 10.3 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Xpo1 PF08389.7 KHN70158.1 - 0.049 13.5 0.7 22 4.9 0.0 3.5 3 1 0 4 4 4 0 Exportin 1-like protein Cnd1 PF12717.2 KHN70158.1 - 0.45 10.3 6.5 2 8.2 0.1 3.1 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SKIP_SNW PF02731.10 KHN70159.1 - 1.5e-08 34.2 1.0 3.4e-08 33.1 0.7 1.6 1 1 0 1 1 1 1 SKIP/SNW domain Chs3p PF12271.3 KHN70160.1 - 9.2e-21 74.0 19.8 1.5e-20 73.3 13.7 1.2 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit ABC_tran PF00005.22 KHN70161.1 - 2e-29 102.6 0.0 4.3e-29 101.5 0.0 1.6 2 0 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 KHN70161.1 - 9.1e-16 58.0 5.9 1.3e-15 57.5 4.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KHN70161.1 - 4.3e-07 29.3 2.0 5.1e-05 22.6 1.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KHN70161.1 - 5.4e-07 29.8 4.1 0.002 18.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KHN70161.1 - 6.5e-05 22.4 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KHN70161.1 - 0.00011 21.6 0.0 0.00029 20.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KHN70161.1 - 0.00016 20.9 0.0 0.00033 19.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KHN70161.1 - 0.00051 19.7 0.1 0.0072 16.0 0.0 2.5 1 1 1 2 2 2 1 NTPase AAA_23 PF13476.1 KHN70161.1 - 0.0022 18.3 0.1 0.006 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 KHN70161.1 - 0.0046 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KHN70161.1 - 0.0051 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 KHN70161.1 - 0.0058 16.5 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KHN70161.1 - 0.011 16.5 0.5 0.31 11.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KHN70161.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 KHN70161.1 - 0.012 15.7 0.1 0.13 12.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KHN70161.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 KHN70161.1 - 0.019 14.3 0.0 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 KHN70161.1 - 0.023 13.4 0.1 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 KHN70161.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KHN70161.1 - 0.085 12.7 1.0 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KHN70161.1 - 0.09 12.9 0.1 0.63 10.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 KHN70161.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KHN70161.1 - 0.15 12.3 1.1 3.3 8.0 0.2 3.2 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.1 KHN70161.1 - 0.23 11.0 0.0 0.99 8.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3397 PF11877.3 KHN70161.1 - 2.5 8.0 7.9 3 7.8 0.1 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF3397) Ribosomal_L31e PF01198.14 KHN70162.1 - 1e-16 60.3 0.7 1.3e-16 59.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DUF1132 PF06575.7 KHN70162.1 - 0.093 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Cpn60_TCP1 PF00118.19 KHN70163.1 - 2.3e-140 468.4 11.3 2.6e-140 468.2 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2837 PF10997.3 KHN70163.1 - 0.16 11.0 1.7 0.57 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2837) PSP1 PF04468.7 KHN70164.1 - 5.5e-31 106.4 0.7 5.5e-31 106.4 0.5 1.9 2 1 0 2 2 2 1 PSP1 C-terminal conserved region TatD_DNase PF01026.16 KHN70165.1 - 2.8e-49 167.6 0.0 3.4e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CENP-C_C PF11699.3 KHN70166.1 - 4.5e-06 26.5 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KHN70166.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Cupin domain DUF3584 PF12128.3 KHN70166.1 - 0.064 10.5 3.4 0.025 11.9 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Mif2_N PF15624.1 KHN70166.1 - 0.31 11.6 2.9 0.38 11.3 0.3 2.1 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal LRR_4 PF12799.2 KHN70167.1 - 1.2e-10 40.7 28.1 0.054 13.1 0.0 8.7 7 2 0 7 7 7 5 Leucine Rich repeats (2 copies) Nbl1_Borealin_N PF10444.4 KHN70167.1 - 0.046 13.0 0.1 0.29 10.5 0.0 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal LRR_8 PF13855.1 KHN70167.1 - 0.076 12.7 29.1 0.072 12.8 0.4 7.4 3 2 5 8 8 8 0 Leucine rich repeat Ribosomal_L28 PF00830.14 KHN70167.1 - 0.22 11.3 7.3 4.7 7.1 0.0 3.2 3 0 0 3 3 3 0 Ribosomal L28 family DUF3185 PF11381.3 KHN70168.1 - 0.78 9.5 19.1 0.34 10.7 0.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3185) DUF1765 PF08578.5 KHN70168.1 - 1.6 8.7 5.3 14 5.7 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1765) Apis_Csd PF11671.3 KHN70168.1 - 2.2 8.0 6.2 35 4.1 0.0 2.4 2 0 0 2 2 2 0 Complementary sex determiner protein PQQ_3 PF13570.1 KHN70169.1 - 0.066 13.5 1.0 4.3 7.7 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Aminotran_1_2 PF00155.16 KHN70171.1 - 8.8e-24 84.1 0.1 1.1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KHN70171.1 - 0.00092 17.5 0.0 0.0013 17.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Thioredoxin PF00085.15 KHN70172.1 - 8.6e-18 63.9 0.1 4.4e-13 48.8 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KHN70172.1 - 1.8e-07 31.1 3.1 0.005 16.6 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.6 KHN70172.1 - 1.4e-05 24.8 0.0 0.013 15.4 0.0 2.9 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.1 KHN70172.1 - 0.00031 20.8 0.2 0.01 15.9 0.3 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KHN70172.1 - 0.0088 15.8 0.8 0.88 9.4 0.5 3.1 2 1 1 3 3 3 1 Thioredoxin domain Thioredoxin_8 PF13905.1 KHN70172.1 - 0.018 15.1 0.1 0.78 9.9 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin-like Redoxin PF08534.5 KHN70172.1 - 0.084 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Redoxin Ribosomal_S8e PF01201.17 KHN70173.1 - 0.14 12.3 0.1 0.14 12.3 0.1 1.8 2 1 0 2 2 2 0 Ribosomal protein S8e HSBP1 PF06825.7 KHN70174.1 - 0.035 13.6 3.5 0.1 12.2 1.4 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 FlaC_arch PF05377.6 KHN70174.1 - 0.044 13.6 0.1 0.085 12.7 0.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MR_MLE PF01188.16 KHN70174.1 - 0.059 13.9 0.1 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain CDC45 PF02724.9 KHN70175.1 - 0.00082 17.5 0.3 0.0025 15.9 0.1 1.8 2 0 0 2 2 2 1 CDC45-like protein Ribosomal_L24e PF01246.15 KHN70176.1 - 2.3e-24 85.0 3.7 4.2e-24 84.2 2.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 KHN70176.1 - 0.00031 20.3 5.7 0.00031 20.3 4.0 1.8 2 0 0 2 2 2 1 MYM-type Zinc finger with FCS sequence motif Ribosomal_L6 PF00347.18 KHN70177.1 - 1.4e-07 31.9 0.0 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 TFIIF_beta PF02270.10 KHN70178.1 - 3.1e-36 125.5 2.4 9.2e-28 97.8 1.0 2.0 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit DUF4065 PF13274.1 KHN70178.1 - 0.066 13.9 0.2 0.25 12.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) DUF3086 PF11285.3 KHN70178.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Dynein_IC2 PF11540.3 KHN70178.1 - 1.7 8.0 4.1 68 2.9 0.1 3.4 3 0 0 3 3 3 0 Cytoplasmic dynein 1 intermediate chain 2 Ribosomal_S17e PF00833.13 KHN70179.1 - 1.1e-40 138.1 1.0 1.2e-40 138.0 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 FliS PF02561.9 KHN70179.1 - 0.046 13.5 0.2 0.059 13.2 0.2 1.2 1 0 0 1 1 1 0 Flagellar protein FliS RdRP_2 PF00978.16 KHN70179.1 - 0.075 11.7 0.2 0.084 11.5 0.1 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Ribonuclease_P PF00825.13 KHN70179.1 - 0.1 12.5 0.2 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Ribonuclease P Peptidase_S24 PF00717.18 KHN70180.1 - 2.9e-09 36.4 0.0 4.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Cu_bind_like PF02298.12 KHN70180.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain Ribosomal_L7Ae PF01248.21 KHN70181.1 - 5.4e-17 61.0 0.1 1e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ubiquitin PF00240.18 KHN70182.1 - 1.1e-34 117.6 0.7 1.2e-34 117.5 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KHN70182.1 - 8.1e-20 70.2 0.6 9e-20 70.1 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KHN70182.1 - 1.8e-06 28.1 0.3 7.1e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KHN70182.1 - 6.4e-05 22.7 0.0 7e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KHN70182.1 - 0.0072 16.4 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KHN70182.1 - 0.015 15.1 0.1 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 KHN70182.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 KHN70182.1 - 0.14 12.1 0.1 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PAP_central PF04928.12 KHN70183.1 - 9.9e-94 312.8 0.0 1.5e-93 312.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KHN70183.1 - 2e-26 92.3 0.4 2e-26 92.3 0.3 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KHN70183.1 - 2.2e-09 37.5 0.1 7.4e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain CBFD_NFYB_HMF PF00808.18 KHN70184.1 - 3.1e-10 39.9 0.8 4.8e-10 39.3 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KHN70184.1 - 1.8e-08 34.3 0.1 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 KHN70184.1 - 1.1e-06 28.3 0.2 1.4e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Peptidase_C3G PF12381.3 KHN70184.1 - 0.04 13.1 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase WD40 PF00400.27 KHN70185.1 - 2.6e-22 77.7 7.2 1.7e-07 30.8 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF3317 PF11779.3 KHN70186.1 - 9.9e-07 28.1 8.2 1.7e-06 27.3 5.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) DnaJ PF00226.26 KHN70188.1 - 1.1e-16 60.2 0.5 1.8e-16 59.6 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain HSCB_C PF07743.8 KHN70188.1 - 0.028 14.8 2.9 0.22 11.9 0.2 2.7 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain AAA PF00004.24 KHN70189.1 - 3.5e-11 43.4 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KHN70189.1 - 7.5e-10 38.7 0.0 1.2e-06 28.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit RuvB_N PF05496.7 KHN70189.1 - 1.7e-08 33.8 0.0 2.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KHN70189.1 - 6.3e-07 29.5 0.2 0.00046 20.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KHN70189.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 KHN70189.1 - 2e-06 27.7 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KHN70189.1 - 7e-06 26.1 0.1 0.00011 22.2 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KHN70189.1 - 1e-05 26.3 0.0 1.4e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KHN70189.1 - 1.6e-05 24.6 0.4 0.0053 16.4 0.4 3.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KHN70189.1 - 4.9e-05 22.5 0.1 0.0027 16.8 0.0 2.4 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KHN70189.1 - 0.00028 20.3 0.0 0.0032 16.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KHN70189.1 - 0.0005 20.3 0.1 0.00087 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KHN70189.1 - 0.00057 19.5 0.0 0.00083 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KHN70189.1 - 0.00062 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 KHN70189.1 - 0.00074 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 KHN70189.1 - 0.00077 18.9 0.0 0.11 11.9 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain Sigma54_activat PF00158.21 KHN70189.1 - 0.0014 18.1 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 KHN70189.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 KHN70189.1 - 0.0018 17.5 0.0 0.2 10.8 0.0 2.2 1 1 1 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 KHN70189.1 - 0.0041 17.0 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KHN70189.1 - 0.012 14.3 0.0 0.023 13.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KHN70189.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KHN70189.1 - 0.042 13.3 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rb_C PF08934.5 KHN70189.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Rb C-terminal domain Arch_ATPase PF01637.13 KHN70189.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 KHN70189.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 NACHT domain KaiC PF06745.8 KHN70189.1 - 0.085 11.9 0.1 0.41 9.7 0.0 1.9 1 1 1 2 2 2 0 KaiC Hydrolase_6 PF13344.1 KHN70189.1 - 0.096 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase AAA_11 PF13086.1 KHN70189.1 - 0.13 11.8 0.1 0.3 10.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KHN70189.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_13 PF13166.1 KHN70189.1 - 0.17 10.3 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KHN70190.1 - 9.3e-42 142.3 0.0 1.6e-40 138.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN70190.1 - 7.6e-28 96.2 0.7 7.7e-27 92.9 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN70190.1 - 9.4e-05 22.3 0.0 0.00039 20.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KHN70190.1 - 0.0018 18.2 0.0 0.0084 16.0 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain DUF1253 PF06862.7 KHN70190.1 - 0.0039 15.6 0.1 0.012 13.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) Muskelin_N PF06588.6 KHN70191.1 - 3.4e-70 235.8 1.3 7.1e-70 234.7 0.9 1.5 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 KHN70191.1 - 2.4e-18 65.7 2.0 1.5e-05 24.9 0.1 7.4 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KHN70191.1 - 8.3e-16 57.5 2.9 0.0009 19.1 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 KHN70191.1 - 1.1e-13 50.6 4.2 0.018 15.1 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 KHN70191.1 - 5e-12 45.3 6.1 0.0015 18.2 0.0 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 KHN70191.1 - 7.1e-12 44.5 8.7 0.024 14.4 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 KHN70191.1 - 1.8e-08 33.7 7.7 0.022 14.3 0.0 5.1 5 0 0 5 5 5 3 Kelch motif F5_F8_type_C PF00754.20 KHN70191.1 - 2.4e-06 27.4 0.0 6.9e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Ribosomal_L38e PF01781.13 KHN70191.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L38e protein family PH PF00169.24 KHN70192.1 - 0.00066 19.8 0.2 0.0016 18.6 0.2 1.8 1 1 0 1 1 1 1 PH domain HALZ PF02183.13 KHN70193.1 - 2.1e-05 24.1 1.6 5.7e-05 22.7 1.1 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIVA PF05103.8 KHN70193.1 - 5.4e-05 23.2 0.5 0.00011 22.2 0.3 1.4 1 0 0 1 1 1 1 DivIVA protein CPSF_A PF03178.10 KHN70193.1 - 0.00038 19.6 0.0 0.0021 17.2 0.0 2.1 2 1 0 2 2 2 1 CPSF A subunit region DUF1875 PF08961.5 KHN70193.1 - 0.0017 17.7 0.3 0.0033 16.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) CNH PF00780.17 KHN70193.1 - 0.0098 15.3 0.0 0.033 13.5 0.0 2.0 2 1 0 2 2 2 1 CNH domain DUF972 PF06156.8 KHN70193.1 - 0.017 15.4 1.8 0.018 15.3 0.2 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KHN70193.1 - 0.037 13.5 1.4 0.12 11.8 0.9 1.9 1 0 0 1 1 1 0 Septum formation initiator NYD-SP28_assoc PF14775.1 KHN70193.1 - 0.044 13.4 4.8 0.33 10.6 2.4 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain TLE_N PF03920.10 KHN70193.1 - 0.05 13.4 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain bZIP_1 PF00170.16 KHN70193.1 - 0.055 13.4 1.6 0.13 12.2 1.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor LVIVD PF08309.6 KHN70193.1 - 0.07 12.1 0.8 0.38 9.7 0.1 2.3 2 0 0 2 2 2 0 LVIVD repeat Cse1 PF08506.5 KHN70194.1 - 3.2e-05 22.6 5.8 0.0029 16.2 2.6 3.4 1 1 1 2 2 2 2 Cse1 Leo1 PF04004.8 KHN70195.1 - 8.8e-05 22.2 0.1 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Leo1-like protein Ribosomal_L5_C PF00673.16 KHN70196.1 - 8.8e-20 70.2 0.0 3e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KHN70196.1 - 7.2e-18 64.1 0.3 1.2e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 MMPL PF03176.10 KHN70197.1 - 0.098 11.3 0.5 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 MMPL family LRR_4 PF12799.2 KHN70198.1 - 3.2e-11 42.6 9.1 0.002 17.7 0.1 7.0 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KHN70198.1 - 2.1e-07 30.0 19.7 10 6.6 0.2 9.8 6 3 2 8 8 8 4 Leucine Rich Repeat LRR_8 PF13855.1 KHN70198.1 - 2.3e-07 30.4 11.1 0.029 14.1 0.1 6.1 2 2 3 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KHN70198.1 - 5.6e-05 22.7 10.4 16 5.9 0.0 8.1 9 0 0 9 9 9 1 Leucine Rich repeat LRR_7 PF13504.1 KHN70198.1 - 0.6 10.5 15.2 92 3.9 0.0 8.0 9 1 0 9 9 9 0 Leucine rich repeat Lactamase_B PF00753.22 KHN70199.1 - 1.3e-14 54.3 0.6 4e-14 52.7 0.4 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KHN70199.1 - 0.00093 18.7 0.1 0.0017 17.8 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta-Casp PF10996.3 KHN70200.1 - 0.0035 17.2 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Beta-Casp domain Pkinase PF00069.20 KHN70202.1 - 7.5e-53 179.3 1.4 8.4e-51 172.6 1.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70202.1 - 7.5e-28 97.3 0.7 6e-27 94.3 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KHN70202.1 - 0.018 14.1 0.0 0.089 11.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KHN70202.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adap_comp_sub PF00928.16 KHN70203.1 - 1.9e-14 53.3 2.1 3e-14 52.7 1.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RRM_1 PF00076.17 KHN70204.1 - 7.6e-16 57.5 0.0 8.8e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN70204.1 - 3.7e-12 46.0 0.0 4.3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70204.1 - 7.7e-09 35.2 0.1 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KHN70204.1 - 0.079 12.7 0.1 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Limkain b1 Cpn60_TCP1 PF00118.19 KHN70205.1 - 1.9e-105 353.3 9.7 2.2e-105 353.1 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 KHN70206.1 - 2.6e-52 177.5 1.7 2.6e-52 177.5 0.3 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70206.1 - 9.1e-23 80.6 0.9 1.3e-22 80.0 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN70206.1 - 0.00012 21.1 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KHN70206.1 - 0.0023 17.7 0.0 0.025 14.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KHN70206.1 - 0.0059 15.9 0.1 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family MRP-63 PF14978.1 KHN70206.1 - 0.015 15.7 0.0 9.6 6.7 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Kdo PF06293.9 KHN70206.1 - 0.025 13.6 0.1 0.078 12.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I PF08311.7 KHN70206.1 - 1.1 9.0 5.4 1.9 8.2 1.1 3.0 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 DUF2205 PF10224.4 KHN70207.1 - 0.0093 15.5 0.2 0.023 14.2 0.2 1.6 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) HTS PF04204.11 KHN70207.1 - 0.02 13.6 0.3 0.036 12.7 0.2 1.4 1 0 0 1 1 1 0 Homoserine O-succinyltransferase HALZ PF02183.13 KHN70207.1 - 0.52 10.0 2.9 0.29 10.8 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 KHN70207.1 - 0.54 10.0 2.7 1.3 8.8 1.9 1.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.16 KHN70207.1 - 0.81 9.6 4.8 0.22 11.4 1.1 1.7 2 0 0 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.6 KHN70207.1 - 0.91 9.2 6.1 1.5 8.5 2.8 2.1 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region CIAPIN1 PF05093.8 KHN70208.1 - 5.8e-17 61.6 11.1 7.9e-15 54.7 2.6 2.3 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis LIM PF00412.17 KHN70208.1 - 0.35 10.9 7.5 0.55 10.3 5.2 1.2 1 0 0 1 1 1 0 LIM domain PC_rep PF01851.17 KHN70209.1 - 2.6e-21 74.5 12.1 0.00026 21.0 0.1 9.3 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KHN70209.1 - 2.4e-11 43.7 0.0 9.6e-06 25.7 0.0 4.4 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 KHN70209.1 - 0.00043 20.1 0.1 2.1 8.6 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KHN70209.1 - 0.0024 18.3 0.1 6.1 7.4 0.0 3.5 2 1 0 2 2 2 2 HEAT-like repeat Nucleoporin2 PF04096.9 KHN70211.1 - 4.9e-14 52.3 0.1 8.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase TFIIA_gamma_C PF02751.9 KHN70212.1 - 6.2e-08 32.3 0.3 8.8e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KHN70212.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain GSHPx PF00255.14 KHN70213.1 - 8.9e-28 95.8 1.2 1.7e-27 94.9 0.8 1.4 1 1 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KHN70213.1 - 0.0045 16.6 0.2 0.013 15.1 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Sec1 PF00995.18 KHN70214.1 - 1.6e-42 145.8 7.6 9.4e-32 110.3 2.2 3.4 2 1 0 2 2 2 2 Sec1 family Myb_DNA-bind_6 PF13921.1 KHN70215.1 - 1.3e-19 70.0 0.2 1.9e-13 50.2 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KHN70215.1 - 2.4e-15 56.3 0.5 2.8e-09 36.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 KHN70215.1 - 0.00071 19.4 0.3 0.049 13.5 0.0 2.2 2 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 KHN70215.1 - 3.5 7.8 6.0 2 8.5 0.5 3.1 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ras PF00071.17 KHN70216.1 - 4.5e-39 133.4 0.0 5.4e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN70216.1 - 1e-10 42.1 0.0 1.5e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN70216.1 - 1.7e-09 37.1 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN70216.1 - 0.00019 20.6 0.0 0.00024 20.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KHN70216.1 - 0.0086 15.3 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KHN70216.1 - 0.11 11.9 0.7 3.2 7.2 0.3 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation XPG_I PF00867.13 KHN70217.1 - 8.3e-10 38.5 0.0 2.6e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region TAP42 PF04177.7 KHN70218.1 - 0.0011 17.9 7.0 0.15 10.9 0.5 2.7 2 1 1 3 3 3 3 TAP42-like family Plus-3 PF03126.13 KHN70219.1 - 5.9e-10 39.1 0.1 1.6e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain Proteasome PF00227.21 KHN70221.1 - 1e-33 116.2 0.0 1.1e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase PF00702.21 KHN70222.1 - 7.9e-28 98.3 0.0 1.2e-27 97.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KHN70222.1 - 2.7e-24 86.4 0.1 5.3e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KHN70222.1 - 5.5e-17 61.5 0.1 5.5e-17 61.5 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KHN70222.1 - 2.7e-10 40.0 0.2 7.8e-10 38.5 0.1 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KHN70222.1 - 2.7e-05 23.8 0.2 0.023 14.2 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Plasmodium_Vir PF05795.6 KHN70222.1 - 0.048 12.8 0.6 0.097 11.8 0.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apc1 PF12859.2 KHN70222.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF4083 PF13314.1 KHN70222.1 - 0.54 10.1 7.4 0.34 10.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) zf-C2H2_jaz PF12171.3 KHN70224.1 - 2.8e-07 30.4 1.3 2.8e-07 30.4 0.9 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KHN70224.1 - 0.00026 21.0 0.3 0.00063 19.8 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 KHN70224.1 - 0.042 13.8 0.2 0.077 13.0 0.1 1.5 1 0 0 1 1 1 0 zinc-finger zf-C2H2_2 PF12756.2 KHN70224.1 - 0.042 13.9 0.3 0.054 13.6 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C3HC4_2 PF13923.1 KHN70224.1 - 0.051 13.6 0.2 0.087 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 KHN70224.1 - 0.067 13.5 0.7 0.21 11.9 0.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type DnaJ PF00226.26 KHN70225.1 - 1.8e-11 43.5 0.5 2.7e-11 43.0 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.24 KHN70226.1 - 3.8e-17 62.7 0.0 7.5e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KHN70226.1 - 6.9e-16 58.3 0.1 3.7e-13 49.4 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 KHN70226.1 - 2.2e-10 40.8 0.4 1.3e-05 25.3 0.0 3.0 2 2 2 4 4 3 2 AAA domain RuvB_N PF05496.7 KHN70226.1 - 1.1e-08 34.4 0.1 2.3e-07 30.1 0.0 2.3 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KHN70226.1 - 1.4e-07 31.6 0.1 6.8e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KHN70226.1 - 3.5e-07 30.1 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KHN70226.1 - 5.7e-07 28.9 0.2 1.5e-05 24.2 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KHN70226.1 - 8e-07 28.1 0.1 0.015 14.0 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 KHN70226.1 - 1.2e-06 28.3 0.1 1e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Replication factor C C-terminal domain RNA_helicase PF00910.17 KHN70226.1 - 2.1e-06 27.8 0.0 9.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 KHN70226.1 - 3.8e-06 26.6 0.1 3.1e-05 23.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 KHN70226.1 - 7.1e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KHN70226.1 - 2.4e-05 23.9 1.7 0.00039 20.0 0.4 2.5 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KHN70226.1 - 4.1e-05 24.3 0.0 8.4e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KHN70226.1 - 7.9e-05 22.3 0.3 0.00021 20.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KHN70226.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN70226.1 - 0.00023 21.0 0.0 0.00078 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KHN70226.1 - 0.00029 20.3 0.5 0.01 15.3 0.0 2.7 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.1 KHN70226.1 - 0.00055 20.2 0.0 0.0019 18.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain PIF1 PF05970.9 KHN70226.1 - 0.0008 18.4 0.3 0.056 12.3 0.1 2.3 1 1 1 2 2 2 1 PIF1-like helicase AAA_19 PF13245.1 KHN70226.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 KHN70226.1 - 0.0026 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KHN70226.1 - 0.0041 16.5 0.4 0.2 11.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 KHN70226.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KHN70226.1 - 0.0056 16.1 0.1 0.031 13.6 0.1 2.2 2 1 0 2 2 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 KHN70226.1 - 0.008 15.6 0.1 0.085 12.2 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain Thymidylate_kin PF02223.12 KHN70226.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase MCM PF00493.18 KHN70226.1 - 0.024 13.4 0.1 0.051 12.3 0.0 1.5 1 1 0 1 1 1 0 MCM2/3/5 family SRP54 PF00448.17 KHN70226.1 - 0.025 14.0 0.1 0.8 9.1 0.0 2.6 1 1 1 3 3 3 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KHN70226.1 - 0.026 14.1 0.0 0.2 11.2 0.0 2.1 1 1 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 KHN70226.1 - 0.03 13.8 0.2 0.096 12.1 0.1 1.9 1 1 0 1 1 1 0 FtsK/SpoIIIE family SNF2_N PF00176.18 KHN70226.1 - 0.03 13.1 0.0 0.058 12.1 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain NTPase_1 PF03266.10 KHN70226.1 - 0.045 13.4 0.2 0.21 11.2 0.0 2.0 1 1 1 2 2 2 0 NTPase T2SE PF00437.15 KHN70226.1 - 0.047 12.5 0.1 0.42 9.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein PSII_Pbs27 PF13326.1 KHN70226.1 - 0.052 13.5 0.1 16 5.4 0.0 2.6 2 1 0 2 2 2 0 Photosystem II Pbs27 DUF815 PF05673.8 KHN70226.1 - 0.058 12.3 0.0 0.13 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 KHN70226.1 - 0.06 12.5 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KHN70226.1 - 0.085 12.3 0.2 5 6.5 0.0 2.6 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 KHN70226.1 - 0.1 12.9 0.2 0.75 10.0 0.1 2.5 1 1 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 KHN70226.1 - 0.1 12.1 0.0 0.29 10.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KHN70226.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GIT_SHD PF08518.6 KHN70228.1 - 6.6e-06 25.3 0.1 0.00021 20.5 0.0 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GATA PF00320.22 KHN70229.1 - 4e-16 58.0 7.4 4e-16 58.0 5.1 2.8 2 1 0 2 2 2 1 GATA zinc finger ArfGap PF01412.13 KHN70229.1 - 0.0098 15.6 12.7 0.016 15.0 1.0 3.0 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf RRM_1 PF00076.17 KHN70230.1 - 2.9e-36 122.9 0.7 2.6e-13 49.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN70230.1 - 9e-23 80.0 0.3 1.2e-07 31.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70230.1 - 5.8e-18 64.4 0.1 8.5e-09 35.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 KHN70230.1 - 0.0037 17.2 0.0 1.3 9.0 0.0 2.7 3 0 0 3 3 3 2 RNA binding domain Limkain-b1 PF11608.3 KHN70230.1 - 0.064 13.0 0.1 0.43 10.3 0.0 2.2 2 1 0 2 2 2 0 Limkain b1 WD40 PF00400.27 KHN70231.1 - 1.6e-25 87.9 1.0 2.1e-06 27.3 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Sof1 PF04158.9 KHN70231.1 - 3.8e-14 52.4 5.8 3.8e-14 52.4 4.0 2.2 2 0 0 2 2 2 1 Sof1-like domain CNH PF00780.17 KHN70231.1 - 0.057 12.8 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 CNH domain La PF05383.12 KHN70232.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 La domain DUF1863 PF08937.6 KHN70233.1 - 0.034 14.1 0.2 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Sipho_Gp157 PF05565.6 KHN70234.1 - 0.026 14.1 2.2 0.026 14.1 1.5 2.9 2 1 0 3 3 3 0 Siphovirus Gp157 Cid2 PF09774.4 KHN70234.1 - 0.03 14.4 2.9 0.031 14.3 1.0 1.8 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Prefoldin_2 PF01920.15 KHN70234.1 - 0.051 13.3 1.0 0.051 13.3 0.7 2.5 3 0 0 3 3 3 0 Prefoldin subunit DUF972 PF06156.8 KHN70234.1 - 0.079 13.3 1.1 0.079 13.3 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Nnf1 PF03980.9 KHN70234.1 - 0.09 12.7 5.8 0.086 12.8 1.7 2.6 2 1 0 2 2 2 0 Nnf1 DUF1664 PF07889.7 KHN70234.1 - 0.22 11.2 7.3 0.32 10.8 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-H PF05837.7 KHN70234.1 - 0.23 11.6 8.3 0.31 11.2 0.6 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) IncA PF04156.9 KHN70234.1 - 0.35 10.4 5.1 0.18 11.3 1.9 1.7 1 1 0 2 2 2 0 IncA protein SecIII_SopE_N PF05364.9 KHN70234.1 - 0.43 10.4 5.9 0.89 9.4 0.0 3.2 2 1 1 3 3 3 0 Salmonella type III secretion SopE effector N-terminus DUF3647 PF12363.3 KHN70234.1 - 0.55 10.3 8.1 0.21 11.6 0.3 3.3 2 2 1 3 3 3 0 Phage protein DUF4200 PF13863.1 KHN70234.1 - 2.6 7.9 10.2 0.43 10.5 3.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 KHN70234.1 - 4.1 7.5 9.6 1.3 9.1 1.5 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Taxilin PF09728.4 KHN70234.1 - 4.8 6.1 12.7 0.22 10.5 1.6 2.5 1 1 0 2 2 2 0 Myosin-like coiled-coil protein Seryl_tRNA_N PF02403.17 KHN70234.1 - 5.3 7.0 10.8 0.28 11.2 0.4 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tho2 PF11262.3 KHN70234.1 - 8.2 5.3 12.7 0.26 10.2 2.3 2.4 1 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 LNS2 PF08235.8 KHN70235.1 - 4.1e-69 231.1 0.0 6e-69 230.6 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KHN70235.1 - 5e-34 116.2 0.3 1.2e-33 115.1 0.2 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region DUF4479 PF14794.1 KHN70235.1 - 0.0023 17.4 0.0 0.0068 15.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4479) Acid_phosphat_B PF03767.9 KHN70235.1 - 0.0026 17.1 0.1 0.0087 15.4 0.1 1.8 1 1 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) SOBP PF15279.1 KHN70236.1 - 0.002 18.5 7.8 0.0023 18.3 5.4 1.0 1 0 0 1 1 1 1 Sine oculis-binding protein Zip PF02535.17 KHN70236.1 - 0.19 10.7 0.6 0.25 10.3 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cript PF10235.4 KHN70236.1 - 3.4 8.0 7.0 17 5.8 0.1 2.9 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT CDC45 PF02724.9 KHN70236.1 - 5.8 4.8 12.5 7.7 4.4 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PSI_PsaF PF02507.10 KHN70237.1 - 0.022 14.3 0.6 0.14 11.6 0.2 2.2 1 1 0 2 2 2 0 Photosystem I reaction centre subunit III DUF2408 PF10303.4 KHN70237.1 - 0.041 13.9 8.1 0.15 12.2 5.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) RIH_assoc PF08454.6 KHN70237.1 - 0.054 13.1 2.6 0.12 12.0 1.8 1.6 1 0 0 1 1 1 0 RyR and IP3R Homology associated Fzo_mitofusin PF04799.8 KHN70237.1 - 1.1 8.5 7.0 0.47 9.8 1.8 2.2 1 1 1 2 2 2 0 fzo-like conserved region ALMT PF11744.3 KHN70237.1 - 5.5 5.5 9.5 1.6 7.2 4.2 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF1833 PF08875.6 KHN70239.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Ran_BP1 PF00638.13 KHN70240.1 - 9.6e-19 67.6 0.4 1.8e-18 66.7 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain Nup54 PF13874.1 KHN70241.1 - 0.042 13.5 1.5 0.081 12.5 1.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Branch PF02485.16 KHN70241.1 - 0.41 9.7 2.2 2.1 7.4 1.6 1.9 1 1 0 1 1 1 0 Core-2/I-Branching enzyme CLTH PF10607.4 KHN70243.1 - 2.6e-07 30.4 1.3 8e-07 28.8 0.9 1.8 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Cauli_AT PF03233.8 KHN70243.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Aphid transmission protein HSP70 PF00012.15 KHN70244.1 - 1.1e-99 334.0 1.9 1.4e-99 333.6 1.3 1.1 1 0 0 1 1 1 1 Hsp70 protein MgtE_N PF03448.12 KHN70245.1 - 3.9e-08 33.5 6.6 4.2e-05 23.8 0.3 2.7 2 1 2 4 4 4 2 MgtE intracellular N domain FliG_M PF14841.1 KHN70245.1 - 0.0021 17.9 0.1 2.9 7.9 0.0 3.5 1 1 2 3 3 3 2 FliG middle domain DUF4301 PF14134.1 KHN70245.1 - 0.037 12.5 3.7 0.03 12.9 1.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Baculo_LEF-11 PF06385.7 KHN70245.1 - 0.084 12.9 0.3 0.084 12.9 0.2 2.3 2 1 0 2 2 2 0 Baculovirus LEF-11 protein DUF1056 PF06341.6 KHN70246.1 - 0.075 13.0 9.0 0.35 10.9 6.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1056) Ribosomal_S8e PF01201.17 KHN70247.1 - 1.5e-36 125.4 5.1 1.8e-36 125.1 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e YihI PF04220.7 KHN70247.1 - 0.95 8.7 3.5 1.5 8.0 2.4 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) PHD PF00628.24 KHN70248.1 - 3.1e-08 33.1 5.5 3.9e-08 32.8 2.5 2.0 2 0 0 2 2 2 1 PHD-finger Ribosomal_S25 PF03297.10 KHN70248.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 1 1 2 2 2 0 S25 ribosomal protein Ftsk_gamma PF09397.5 KHN70248.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain HTH_24 PF13412.1 KHN70248.1 - 0.11 11.9 0.2 0.21 10.9 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 KHN70248.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain PHD_2 PF13831.1 KHN70248.1 - 0.19 11.1 6.6 0.34 10.2 2.6 2.4 2 1 0 2 2 2 0 PHD-finger Fijivirus_P9-2 PF06837.6 KHN70248.1 - 1.2 8.2 6.4 0.82 8.7 1.3 2.0 1 1 1 2 2 2 0 Fijivirus P9-2 protein Zn_ribbon_recom PF13408.1 KHN70248.1 - 4.4 7.6 10.7 1.7 8.9 4.5 2.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L35Ae PF01247.13 KHN70249.1 - 5.7e-21 74.0 0.4 6.9e-21 73.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KHN70249.1 - 0.0023 17.8 0.0 1.5 8.8 0.0 2.9 2 1 0 2 2 2 2 RimM N-terminal domain MAD PF05557.8 KHN70251.1 - 9.4e-17 60.3 0.4 9.4e-17 60.3 0.2 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein Chordopox_E11 PF06138.7 KHN70251.1 - 0.018 15.1 1.0 0.099 12.7 0.7 2.1 1 1 0 1 1 1 0 Chordopoxvirus E11 protein Hormone_3 PF00159.13 KHN70251.1 - 0.041 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide Propeptide_C1 PF08127.8 KHN70251.1 - 0.12 12.0 0.1 0.36 10.4 0.1 1.8 1 0 0 1 1 1 0 Peptidase family C1 propeptide RVT_3 PF13456.1 KHN70251.1 - 0.21 11.4 2.0 0.95 9.2 0.0 2.3 2 1 0 2 2 2 0 Reverse transcriptase-like DUF4200 PF13863.1 KHN70251.1 - 0.3 11.0 4.3 0.45 10.4 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Med30 PF11315.3 KHN70251.1 - 0.38 10.8 4.5 0.59 10.2 3.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 bZIP_2 PF07716.10 KHN70251.1 - 0.48 10.2 4.0 12 5.7 0.2 2.5 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.16 KHN70251.1 - 1.2 9.0 5.5 2.4 8.1 0.3 2.6 3 0 0 3 3 3 0 bZIP transcription factor DUF904 PF06005.7 KHN70251.1 - 4.5 7.6 10.1 37 4.7 7.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Suf PF05843.9 KHN70252.1 - 5.8e-12 45.9 7.6 4.8e-11 42.9 0.2 3.1 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.1 KHN70252.1 - 0.0031 16.6 0.0 0.18 10.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Pyr_redox_2 PF07992.9 KHN70253.1 - 7e-26 91.3 0.3 9.7e-26 90.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KHN70253.1 - 1e-11 45.0 1.0 4.7e-11 42.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KHN70253.1 - 5.8e-09 36.3 0.1 2.3e-08 34.3 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KHN70253.1 - 1.6e-05 23.9 0.1 0.00035 19.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KHN70253.1 - 0.00016 20.7 0.1 0.34 9.7 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 KHN70253.1 - 0.0002 20.3 0.4 1.8 7.3 0.0 3.7 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KHN70253.1 - 0.001 18.0 0.4 1.1 8.0 0.0 3.5 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.9 KHN70253.1 - 0.0031 16.0 0.1 5.4 5.3 0.0 3.2 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.1 KHN70253.1 - 0.0045 15.9 0.1 2.1 7.1 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KHN70253.1 - 0.0054 16.9 0.1 0.029 14.6 0.1 2.2 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 KHN70253.1 - 0.013 14.6 0.3 3.1 6.8 0.1 2.4 2 0 0 2 2 2 0 Thi4 family Bclx_interact PF08945.5 KHN70253.1 - 0.088 12.3 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain NAD_binding_9 PF13454.1 KHN70253.1 - 0.095 12.4 0.3 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF2795 PF11387.3 KHN70254.1 - 0.0088 15.8 0.2 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2795) EMP24_GP25L PF01105.19 KHN70255.1 - 1.9e-08 34.2 1.0 2.5e-08 33.8 0.7 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3203 PF11462.3 KHN70255.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) DUF2819 PF10995.3 KHN70255.1 - 0.098 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) TRAPP PF04051.11 KHN70256.1 - 8.5e-11 41.5 0.4 2.1e-10 40.2 0.3 1.6 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Archease PF01951.11 KHN70257.1 - 1.6e-18 66.9 0.4 1.9e-18 66.7 0.3 1.1 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) FlgN PF05130.7 KHN70258.1 - 0.0092 16.2 1.1 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 FlgN protein Neur_chan_memb PF02932.11 KHN70258.1 - 0.091 12.6 2.6 0.098 12.5 1.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rad17 PF03215.10 KHN70259.1 - 0.0001 21.1 0.3 0.034 12.8 0.0 2.7 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein HTH_25 PF13413.1 KHN70259.1 - 0.16 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CLTH PF10607.4 KHN70260.1 - 1.1e-10 41.3 4.5 1.4e-10 41.0 2.4 1.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KHN70260.1 - 0.00011 21.8 0.1 0.00037 20.1 0.1 1.9 2 0 0 2 2 2 1 LisH LSM PF01423.17 KHN70261.1 - 3.3e-05 23.3 0.2 6.1e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 LSM domain Sel1 PF08238.7 KHN70262.1 - 1.5e-09 38.1 17.1 0.0044 17.6 0.0 4.1 4 0 0 4 4 4 3 Sel1 repeat TPR_11 PF13414.1 KHN70262.1 - 6e-05 22.6 11.8 0.015 14.8 0.1 4.9 5 1 1 6 6 6 2 TPR repeat Gti1_Pac2 PF09729.4 KHN70263.1 - 1.2e-34 119.5 1.3 2e-30 105.8 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family NAC PF01849.13 KHN70264.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAC domain PPTA PF01239.17 KHN70265.1 - 4.4e-17 60.6 7.3 5.6e-09 34.9 0.1 3.9 3 1 1 4 4 4 2 Protein prenyltransferase alpha subunit repeat Pfg27 PF09216.5 KHN70265.1 - 0.033 13.7 1.3 0.086 12.4 0.1 2.3 3 0 0 3 3 3 0 Pfg27 BOP1NT PF08145.7 KHN70266.1 - 0.00031 20.5 0.2 0.00031 20.5 0.1 2.2 1 1 1 2 2 2 1 BOP1NT (NUC169) domain Omp28 PF11551.3 KHN70266.1 - 0.046 13.2 0.9 0.11 11.9 0.6 1.6 1 0 0 1 1 1 0 Outer membrane protein Omp28 ubiquitin PF00240.18 KHN70267.1 - 7.8e-34 114.8 1.0 1.1e-33 114.3 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KHN70267.1 - 7.6e-20 70.3 0.7 1.1e-19 69.8 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KHN70267.1 - 2e-05 24.7 0.2 7.2e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KHN70267.1 - 0.00015 21.5 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KHN70267.1 - 0.0011 18.8 0.4 0.0024 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KHN70267.1 - 0.0033 17.5 0.1 0.0043 17.2 0.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ribosomal_S27 PF01599.14 KHN70267.1 - 0.096 12.5 5.7 0.15 11.9 4.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S27a DUF2870 PF11069.3 KHN70267.1 - 0.11 12.5 0.3 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) zf-HIT PF04438.11 KHN70267.1 - 3.4 7.3 10.0 14 5.3 7.0 1.9 1 1 0 1 1 1 0 HIT zinc finger Helicase_C_2 PF13307.1 KHN70268.1 - 2e-51 174.2 0.0 7.7e-51 172.3 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KHN70268.1 - 4.9e-47 159.5 0.4 8.7e-47 158.7 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KHN70268.1 - 0.0001 21.8 0.0 0.0009 18.7 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 KHN70268.1 - 0.0012 18.4 0.2 0.0084 15.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KHN70268.1 - 0.0036 17.1 0.1 0.044 13.5 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KHN70268.1 - 0.077 12.7 0.0 0.62 9.8 0.0 2.5 3 0 0 3 3 3 0 Part of AAA domain HSP90 PF00183.13 KHN70269.1 - 2.5e-126 422.2 24.1 4.1e-126 421.5 16.7 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KHN70269.1 - 1.6e-13 50.5 0.1 5e-13 48.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KHN70269.1 - 3.9e-08 33.0 0.0 9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PI3_PI4_kinase PF00454.22 KHN70271.1 - 8.8e-42 143.1 1.8 1.3e-41 142.6 0.3 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KHN70271.1 - 3.7e-10 39.0 0.0 9.3e-10 37.7 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.1 KHN70271.1 - 0.069 12.9 1.6 0.35 10.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 KHN70271.1 - 0.14 12.6 0.2 0.7 10.4 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 KHN70271.1 - 0.15 12.4 0.1 0.5 10.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SPC25 PF06703.6 KHN70272.1 - 6.8e-17 61.5 1.9 1.1e-16 60.8 1.3 1.3 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Frag1 PF10277.4 KHN70272.1 - 0.0046 16.4 0.3 0.0058 16.1 0.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Germane PF10646.4 KHN70272.1 - 0.034 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Sporulation and spore germination MCM PF00493.18 KHN70273.1 - 1.1e-130 435.3 0.1 1.7e-130 434.6 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KHN70273.1 - 1.7e-13 51.1 1.2 1.8e-12 47.8 0.1 3.2 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 KHN70273.1 - 1.1e-06 28.4 0.0 4.4e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KHN70273.1 - 1.8e-06 27.2 0.1 3.6e-05 23.0 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KHN70273.1 - 0.0011 18.5 0.0 0.0059 16.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) tRNA_anti-codon PF01336.20 KHN70273.1 - 0.0041 16.9 0.1 0.36 10.7 0.0 2.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Sigma54_activat PF00158.21 KHN70273.1 - 0.0066 15.9 0.1 0.82 9.1 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_pol_Rpb2_4 PF04566.8 KHN70273.1 - 0.054 13.3 0.2 1 9.2 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 DUF87 PF01935.12 KHN70273.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 KH_1 PF00013.24 KHN70274.1 - 7.1e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KHN70274.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 KH domain NTF2 PF02136.15 KHN70275.1 - 2e-08 34.6 0.1 2.9e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DNA_pol3_a_NII PF11490.3 KHN70275.1 - 0.069 12.7 0.1 2 8.0 0.0 2.5 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II FYRN PF05964.9 KHN70276.1 - 4.2e-15 54.9 0.6 1e-14 53.7 0.3 1.8 2 0 0 2 2 2 1 F/Y-rich N-terminus FYRC PF05965.9 KHN70276.1 - 0.0073 16.0 0.1 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 F/Y rich C-terminus Ribonuclease PF00545.15 KHN70276.1 - 0.023 14.7 0.1 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 ribonuclease SNARE PF05739.14 KHN70277.1 - 0.027 14.1 1.3 0.046 13.4 0.9 1.4 1 0 0 1 1 1 0 SNARE domain DUF357 PF04010.8 KHN70277.1 - 0.13 11.9 1.3 0.23 11.2 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF357) Fib_alpha PF08702.5 KHN70277.1 - 0.96 9.5 5.4 4.2 7.4 0.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Homeobox PF00046.24 KHN70278.1 - 3.3e-10 39.4 0.5 6.1e-10 38.5 0.3 1.4 1 0 0 1 1 1 1 Homeobox domain BrkDBD PF09607.5 KHN70278.1 - 0.11 12.0 0.2 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain tRNA-synt_1c PF00749.16 KHN70279.1 - 6e-95 317.5 0.1 1e-94 316.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KHN70279.1 - 1.8e-35 122.1 0.7 3.3e-35 121.2 0.5 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF2977 PF11192.3 KHN70279.1 - 0.043 13.6 1.7 0.85 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) DNA_ligase_A_M PF01068.16 KHN70280.1 - 1.6e-59 200.6 3.4 2.5e-59 200.0 2.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KHN70280.1 - 1.9e-39 135.3 0.4 2.9e-39 134.6 0.3 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KHN70280.1 - 2.1e-23 82.5 0.0 3.8e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 KHN70280.1 - 0.0021 17.7 2.4 0.019 14.6 1.7 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Sec23_trunk PF04811.10 KHN70281.1 - 1.4e-15 57.3 0.0 1.4e-14 54.0 0.0 2.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 KHN70281.1 - 4.8e-14 51.6 0.8 1.1e-13 50.4 0.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 KHN70281.1 - 6.9e-10 38.2 0.0 1.6e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KHN70281.1 - 8.2e-07 29.4 0.0 2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KHN70281.1 - 0.00086 18.9 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Cnd1 PF12717.2 KHN70282.1 - 1.1e-21 77.4 7.4 5.8e-20 71.8 1.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KHN70282.1 - 1.7e-07 30.7 3.1 0.14 12.3 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KHN70282.1 - 6.5e-07 29.5 0.3 0.15 12.3 0.2 4.1 3 1 1 4 4 4 3 HEAT repeats Nipped-B_C PF12830.2 KHN70282.1 - 0.0066 16.1 0.2 0.088 12.4 0.0 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Arm PF00514.18 KHN70282.1 - 0.032 14.0 0.1 94 3.0 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KHN70282.1 - 0.077 13.5 0.3 26 5.4 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat TIP120 PF08623.5 KHN70282.1 - 6.4 6.3 9.7 1.1 8.7 0.4 3.5 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) TAFII28 PF04719.9 KHN70283.1 - 1.4e-28 98.4 0.0 2.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region MIF4G PF02854.14 KHN70284.1 - 0.0049 16.3 0.1 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain DUF760 PF05542.6 KHN70284.1 - 0.036 14.2 0.2 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF760) DAHP_synth_2 PF01474.11 KHN70284.1 - 0.12 10.7 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 Class-II DAHP synthetase family DIM1 PF02966.11 KHN70285.1 - 5.6e-39 132.6 0.3 6.3e-39 132.5 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 GNAT_acetyltran PF12746.2 KHN70286.1 - 0.062 12.1 0.2 0.079 11.7 0.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Cnd2 PF05786.9 KHN70287.1 - 4.3e-51 174.3 9.6 1.3e-28 100.0 0.5 5.0 1 1 2 4 4 4 4 Condensin complex subunit 2 DUF3937 PF13073.1 KHN70287.1 - 0.15 11.9 0.1 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) PMT PF02366.13 KHN70288.1 - 2.5e-54 184.2 21.6 2.5e-54 184.2 14.9 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KHN70288.1 - 5.4e-19 68.4 0.1 9.2e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 MIR domain BRCT PF00533.21 KHN70290.1 - 5.8e-25 87.2 2.0 5e-05 23.3 0.0 6.1 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KHN70290.1 - 3.1e-13 49.3 0.1 0.00068 19.4 0.0 5.5 5 0 0 5 5 5 3 twin BRCT domain V-ATPase_G PF03179.10 KHN70291.1 - 2.4e-07 30.9 7.5 2.7e-07 30.8 5.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PLC-beta_C PF08703.5 KHN70291.1 - 0.00076 19.2 6.8 0.00088 19.0 4.7 1.2 1 0 0 1 1 1 1 PLC-beta C terminal ATP-synt_B PF00430.13 KHN70291.1 - 0.01 15.6 8.5 0.012 15.4 5.9 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Vip3A_N PF12495.3 KHN70291.1 - 0.011 15.3 0.2 0.012 15.2 0.2 1.0 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal OmpH PF03938.9 KHN70291.1 - 0.063 13.2 4.7 0.07 13.0 3.3 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Taeniidae_ag PF05596.6 KHN70291.1 - 0.13 12.0 4.8 1.3 8.8 0.2 3.1 2 2 1 3 3 3 0 Taeniidae antigen Ufd2P_core PF10408.4 KHN70291.1 - 0.15 10.2 1.8 0.2 9.8 1.2 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core AKNA PF12443.3 KHN70291.1 - 0.16 12.0 2.2 0.64 10.0 0.6 1.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor YlqD PF11068.3 KHN70291.1 - 0.17 11.8 6.0 0.22 11.5 4.2 1.1 1 0 0 1 1 1 0 YlqD protein FadA PF09403.5 KHN70291.1 - 0.2 11.6 5.9 0.24 11.3 4.1 1.1 1 0 0 1 1 1 0 Adhesion protein FadA DUF2203 PF09969.4 KHN70291.1 - 0.38 10.9 3.2 0.45 10.7 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TACC PF05010.9 KHN70291.1 - 0.38 10.4 6.8 0.44 10.2 4.7 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF4407 PF14362.1 KHN70291.1 - 0.41 9.5 3.0 0.49 9.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4635 PF15466.1 KHN70291.1 - 0.5 9.6 4.2 0.68 9.2 2.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Caldesmon PF02029.10 KHN70291.1 - 0.51 8.7 10.4 0.54 8.6 7.2 1.0 1 0 0 1 1 1 0 Caldesmon Sds3 PF08598.6 KHN70291.1 - 0.57 9.6 9.4 0.72 9.3 6.5 1.1 1 0 0 1 1 1 0 Sds3-like DUF572 PF04502.8 KHN70291.1 - 0.84 8.8 7.3 0.97 8.5 5.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) OEP PF02321.13 KHN70291.1 - 0.93 9.0 5.0 1.3 8.5 3.5 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DUF883 PF05957.8 KHN70291.1 - 1.1 9.7 6.1 4.4 7.7 4.2 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ThiF PF00899.16 KHN70292.1 - 4.5e-35 120.4 0.1 9.4e-35 119.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.4 KHN70292.1 - 1.6e-13 49.7 1.7 4.3e-13 48.4 1.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBACT PF02134.16 KHN70292.1 - 3.2e-13 49.0 0.6 6.7e-13 48.0 0.4 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein NAD_binding_7 PF13241.1 KHN70292.1 - 0.011 15.9 0.0 0.034 14.4 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 KHN70292.1 - 0.029 14.3 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KHN70292.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KHN70292.1 - 0.095 13.1 0.1 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E2F_TDP PF02319.15 KHN70293.1 - 7.6e-19 67.0 0.9 1.3e-18 66.3 0.0 1.9 3 0 0 3 3 3 1 E2F/DP family winged-helix DNA-binding domain DUF1041 PF06292.12 KHN70293.1 - 0.054 13.6 0.2 0.098 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Phi-29_GP16_7 PF06720.6 KHN70293.1 - 0.076 12.6 1.1 0.11 12.1 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 ProRS-C_1 PF09180.6 KHN70294.1 - 4.3e-24 84.2 1.5 3.7e-23 81.2 1.2 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KHN70294.1 - 2.9e-21 75.8 0.0 1.3e-20 73.7 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KHN70294.1 - 8.9e-19 67.2 0.1 1.8e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain Trehalase PF01204.13 KHN70295.1 - 1.7e-135 452.5 0.6 2.3e-135 452.1 0.4 1.1 1 0 0 1 1 1 1 Trehalase Peptidase_M48 PF01435.13 KHN70296.1 - 6.4e-45 153.4 0.0 9.2e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KHN70296.1 - 3.8e-05 22.8 4.0 3.8e-05 22.8 2.8 2.5 2 1 1 3 3 3 2 BlaR1 peptidase M56 UPF0104 PF03706.8 KHN70296.1 - 0.0022 17.3 0.4 0.0022 17.3 0.3 2.0 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0104) DUF4538 PF15061.1 KHN70296.1 - 0.07 12.4 0.2 0.17 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF955 PF06114.8 KHN70296.1 - 0.11 12.2 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Bac_export_2 PF01312.14 KHN70296.1 - 0.21 10.4 8.8 0.63 8.8 6.1 1.8 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family ERCC4 PF02732.10 KHN70297.1 - 2.8e-25 88.7 0.4 6e-25 87.6 0.3 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 KHN70297.1 - 5e-05 23.4 0.3 0.057 13.6 0.0 2.7 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH_2 PF12826.2 KHN70297.1 - 0.0002 21.1 0.1 0.056 13.3 0.0 3.1 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.1 KHN70297.1 - 0.017 15.3 0.3 0.14 12.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain WD40 PF00400.27 KHN70299.1 - 1.1e-54 180.5 10.9 1.1e-10 40.9 0.2 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KHN70299.1 - 6.2e-07 29.3 0.6 0.028 14.1 0.2 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A GDI PF00996.13 KHN70300.1 - 1.7e-91 306.7 0.5 2.3e-91 306.3 0.4 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DAO PF01266.19 KHN70300.1 - 0.014 14.3 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase RNase_PH PF01138.16 KHN70301.1 - 0.0044 17.3 0.6 0.037 14.3 0.3 2.4 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 ATP_bind_1 PF03029.12 KHN70302.1 - 3.9e-58 196.7 0.2 7.7e-58 195.8 0.1 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KHN70302.1 - 2.6e-05 24.3 0.0 4.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 KHN70302.1 - 3e-05 23.5 0.0 0.00016 21.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 KHN70302.1 - 6e-05 22.5 0.0 0.0074 15.7 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 KHN70302.1 - 6.5e-05 22.6 0.1 0.00057 19.6 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KHN70302.1 - 0.00016 21.5 0.0 0.00047 20.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 KHN70302.1 - 0.00022 20.7 0.0 0.0011 18.5 0.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 KHN70302.1 - 0.00073 18.9 0.0 0.002 17.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.5 KHN70302.1 - 0.0011 18.2 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 KHN70302.1 - 0.0012 19.6 0.0 0.0033 18.2 0.0 1.7 2 1 0 2 2 1 1 AAA domain Arf PF00025.16 KHN70302.1 - 0.0027 16.9 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.1 KHN70302.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KHN70302.1 - 0.0039 16.8 0.1 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KHN70302.1 - 0.0044 15.9 0.1 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 KHN70302.1 - 0.0044 17.3 0.1 0.015 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KHN70302.1 - 0.0076 15.8 0.0 0.041 13.5 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KHN70302.1 - 0.0079 15.4 0.0 0.06 12.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KHN70302.1 - 0.0085 15.5 0.4 0.12 11.9 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 KHN70302.1 - 0.015 15.0 0.1 0.061 13.0 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 KHN70302.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KHN70302.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase T2SE PF00437.15 KHN70302.1 - 0.027 13.3 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 KHN70302.1 - 0.038 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 KHN70302.1 - 0.047 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 KHN70302.1 - 0.069 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 KHN70302.1 - 0.096 12.8 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.1 KHN70302.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KHN70302.1 - 0.12 11.6 0.0 0.74 9.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B ArgK PF03308.11 KHN70302.1 - 0.14 10.9 0.0 3.3 6.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 KHN70302.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 KHN70302.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF663 PF04950.7 KHN70303.1 - 5.5e-20 71.5 1.1 3.9e-19 68.7 0.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF663) Pkinase PF00069.20 KHN70304.1 - 8.3e-62 208.6 0.0 1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70304.1 - 4.8e-27 94.6 0.0 6.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KHN70304.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 KHN70304.1 - 0.029 13.1 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sec23_helical PF04815.10 KHN70305.1 - 8.2e-09 34.8 1.6 2e-08 33.5 0.2 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KHN70305.1 - 6.1e-07 29.8 1.1 1.9e-06 28.2 0.8 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 KHN70305.1 - 4.7e-06 26.2 0.0 9.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 KHN70305.1 - 3.3e-05 23.3 5.4 3.3e-05 23.3 3.8 2.2 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger PRA1 PF03208.14 KHN70306.1 - 2.9e-15 55.9 0.3 3.4e-15 55.7 0.2 1.0 1 0 0 1 1 1 1 PRA1 family protein PrgI PF12666.2 KHN70306.1 - 0.038 14.1 7.6 0.44 10.7 0.0 2.2 1 1 1 2 2 2 0 PrgI family protein AAA_13 PF13166.1 KHN70307.1 - 0.00053 18.5 10.4 0.00059 18.4 7.2 1.0 1 0 0 1 1 1 1 AAA domain MogR_DNAbind PF12181.3 KHN70307.1 - 0.00061 19.5 7.8 0.00073 19.3 0.2 2.1 1 1 1 2 2 2 1 DNA binding domain of the motility gene repressor (MogR) Tropomyosin_1 PF12718.2 KHN70307.1 - 0.00065 19.5 12.2 0.00096 19.0 8.5 1.2 1 0 0 1 1 1 1 Tropomyosin like TMCO5 PF14992.1 KHN70307.1 - 0.0016 17.6 6.6 0.0019 17.4 4.5 1.1 1 0 0 1 1 1 1 TMCO5 family TMPIT PF07851.8 KHN70307.1 - 0.0032 16.5 5.5 0.004 16.2 3.8 1.1 1 0 0 1 1 1 1 TMPIT-like protein Spc7 PF08317.6 KHN70307.1 - 0.004 15.8 7.7 0.0049 15.5 5.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.7 KHN70307.1 - 0.0049 15.1 7.8 0.0071 14.5 5.4 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Rab5-bind PF09311.6 KHN70307.1 - 0.0083 16.0 1.4 0.0083 16.0 1.0 2.3 1 1 1 2 2 2 1 Rabaptin-like protein ATG16 PF08614.6 KHN70307.1 - 0.017 14.9 3.8 0.017 14.9 2.6 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Transcrip_act PF04949.8 KHN70307.1 - 0.025 14.2 9.1 0.044 13.4 6.3 1.5 1 1 0 1 1 1 0 Transcriptional activator CENP_C_N PF15622.1 KHN70307.1 - 0.034 13.4 3.9 0.044 13.0 2.7 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal CALCOCO1 PF07888.6 KHN70307.1 - 0.034 12.4 6.6 0.035 12.4 4.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_TATA_bd PF12325.3 KHN70307.1 - 0.041 13.6 11.9 0.036 13.7 7.3 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 KHN70307.1 - 0.047 13.8 8.5 0.092 12.8 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF869 PF05911.6 KHN70307.1 - 0.052 11.7 10.1 0.063 11.5 7.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DivIC PF04977.10 KHN70307.1 - 0.059 12.8 12.4 1.4 8.4 3.8 2.7 1 1 1 2 2 2 0 Septum formation initiator SseC PF04888.7 KHN70307.1 - 0.069 12.4 1.7 0.091 12.0 1.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ARD PF03079.9 KHN70307.1 - 0.11 12.4 3.6 0.2 11.6 2.5 1.6 1 1 0 1 1 1 0 ARD/ARD' family TelA PF05816.6 KHN70307.1 - 0.12 11.0 11.2 0.23 10.1 6.6 1.8 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) Spc24 PF08286.6 KHN70307.1 - 0.16 11.6 12.7 0.016 14.8 3.6 2.4 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Macoilin PF09726.4 KHN70307.1 - 0.22 9.7 11.2 0.25 9.5 7.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Laminin_II PF06009.7 KHN70307.1 - 0.23 11.1 9.2 1.3 8.7 1.0 2.1 1 1 1 2 2 2 0 Laminin Domain II bZIP_1 PF00170.16 KHN70307.1 - 0.25 11.3 12.4 2 8.4 1.8 2.6 1 1 0 2 2 2 0 bZIP transcription factor TBPIP PF07106.8 KHN70307.1 - 0.26 10.8 14.0 0.13 11.7 7.4 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 KHN70307.1 - 0.27 10.8 9.3 0.4 10.2 6.4 1.3 1 0 0 1 1 1 0 IncA protein DASH_Spc34 PF08657.5 KHN70307.1 - 0.37 10.4 9.2 0.049 13.2 1.2 2.1 1 1 1 2 2 2 0 DASH complex subunit Spc34 ORF6C PF10552.4 KHN70307.1 - 0.4 10.4 9.5 0.1 12.3 1.3 2.5 1 1 1 2 2 2 0 ORF6C domain bZIP_2 PF07716.10 KHN70307.1 - 0.42 10.4 9.6 4.3 7.2 2.2 3.2 2 1 0 2 2 2 0 Basic region leucine zipper HisKA_3 PF07730.8 KHN70307.1 - 0.74 10.2 3.7 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 Histidine kinase DUF342 PF03961.8 KHN70307.1 - 0.77 8.1 8.6 1 7.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 KHN70307.1 - 0.87 9.5 18.5 1.6 8.7 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DMPK_coil PF08826.5 KHN70307.1 - 0.91 9.4 8.7 0.19 11.6 1.2 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like TMF_DNA_bd PF12329.3 KHN70307.1 - 1.6 8.6 19.8 0.28 11.0 7.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KHN70307.1 - 2.1 7.2 13.9 4 6.4 9.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 KHN70307.1 - 2.9 8.2 12.5 2.8 8.3 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ly49 PF08391.5 KHN70307.1 - 3.8 7.6 7.4 2.5 8.2 3.5 1.7 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF1664 PF07889.7 KHN70307.1 - 4.3 7.1 9.6 2.9 7.7 1.8 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PhoU PF01895.14 KHN70307.1 - 6.1 7.3 7.5 7.3 7.1 2.9 2.5 1 1 1 2 2 2 0 PhoU domain ACCA PF03255.9 KHN70307.1 - 7.6 6.0 8.7 4.8 6.7 0.9 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit tRNA-synt_2c PF01411.14 KHN70308.1 - 6.4e-161 536.3 0.0 1.1e-160 535.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KHN70308.1 - 2.8e-13 49.5 0.5 1.4e-12 47.3 0.3 2.3 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TFIID_20kDa PF03847.8 KHN70309.1 - 5e-09 36.3 0.8 6.5e-09 35.9 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TAF4 PF05236.9 KHN70309.1 - 4.3e-06 26.2 0.5 4.8e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Histone PF00125.19 KHN70309.1 - 3.3e-05 23.9 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 KHN70309.1 - 0.00071 19.3 0.0 0.00079 19.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-X PF09415.5 KHN70309.1 - 0.0016 18.2 0.2 0.0049 16.6 0.0 1.7 2 0 0 2 2 2 1 CENP-S associating Centromere protein X TFIID-18kDa PF02269.11 KHN70309.1 - 0.0073 16.0 0.4 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit FANCI_S1-cap PF14674.1 KHN70309.1 - 0.026 14.5 0.2 0.29 11.2 0.1 2.1 1 1 1 2 2 2 0 FANCI solenoid 1 cap CBFD_NFYB_HMF PF00808.18 KHN70309.1 - 0.048 13.7 0.1 0.078 13.0 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ClpB_D2-small PF10431.4 KHN70309.1 - 0.064 13.1 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Motilin_assoc PF04643.7 KHN70309.1 - 0.072 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide EF-hand_like PF09279.6 KHN70309.1 - 0.074 13.0 0.3 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like SAC3 PF12209.3 KHN70310.1 - 0.093 12.8 0.4 1 9.5 0.0 2.5 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain DEAD PF00270.24 KHN70311.1 - 1.8e-32 112.1 4.4 3.7e-32 111.1 0.8 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN70311.1 - 1e-23 82.9 0.0 8.7e-23 79.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KHN70311.1 - 0.00088 18.6 0.5 0.0034 16.7 0.1 2.0 2 0 0 2 2 2 1 SecA DEAD-like domain Helicase_C_2 PF13307.1 KHN70311.1 - 0.0021 18.0 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 KHN70311.1 - 0.0029 17.4 2.7 0.0043 16.9 0.1 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KHN70311.1 - 0.014 15.0 0.2 0.047 13.4 0.2 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KHN70311.1 - 0.023 14.2 0.5 0.066 12.7 0.0 2.0 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 KHN70311.1 - 0.077 11.8 0.5 0.11 11.3 0.4 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 KHN70311.1 - 0.19 11.0 1.9 1 8.5 0.4 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain WD40 PF00400.27 KHN70312.1 - 1.1e-17 63.1 0.0 7.8e-08 31.9 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KHN70312.1 - 5.5e-05 22.9 0.1 0.6 9.9 0.0 3.6 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Per1 PF04080.8 KHN70313.1 - 1.7e-39 135.8 12.6 1.9e-39 135.7 8.7 1.1 1 0 0 1 1 1 1 Per1-like PrgI PF12666.2 KHN70313.1 - 6.5 6.9 10.1 0.72 10.0 0.8 2.8 1 1 2 3 3 3 0 PrgI family protein Aa_trans PF01490.13 KHN70314.1 - 1e-58 198.7 42.9 1.2e-58 198.5 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2238 PF09997.4 KHN70314.1 - 0.15 11.4 7.3 0.13 11.6 1.9 2.8 1 1 2 3 3 3 0 Predicted membrane protein (DUF2238) Streptin-Immun PF11083.3 KHN70315.1 - 0.1 12.5 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein DEAD PF00270.24 KHN70316.1 - 5.1e-41 139.9 0.1 8.5e-41 139.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KHN70316.1 - 1.1e-17 63.6 0.0 2.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KHN70316.1 - 1.2e-05 25.3 0.0 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_19 PF13245.1 KHN70316.1 - 0.0038 16.9 0.1 0.0078 15.9 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 KHN70316.1 - 0.0055 16.5 0.3 0.046 13.5 0.2 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 KHN70316.1 - 0.0056 15.7 2.5 0.01 14.9 0.1 2.4 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 KHN70316.1 - 0.012 15.1 0.1 0.026 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain Thioredoxin_8 PF13905.1 KHN70316.1 - 0.028 14.5 0.2 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Helicase_RecD PF05127.9 KHN70316.1 - 0.074 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase Glycos_transf_1 PF00534.15 KHN70317.1 - 1.2e-25 89.8 0.0 2.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.7 KHN70317.1 - 2.8e-23 82.1 0.6 6.4e-23 80.9 0.2 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.1 KHN70317.1 - 5.8e-14 52.2 0.2 1.7e-13 50.6 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 KHN70317.1 - 5.8e-11 42.6 0.1 1.4e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KHN70317.1 - 1.7e-08 34.7 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KHN70317.1 - 3.4e-05 23.7 0.1 6.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KHN70317.1 - 0.066 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 EF-hand_7 PF13499.1 KHN70318.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 KHN70318.1 - 0.00034 20.1 0.1 0.0048 16.4 0.1 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.1 KHN70318.1 - 0.00088 19.1 0.1 2.2 8.2 0.0 3.0 1 1 2 3 3 3 2 EF-hand domain EF-hand_6 PF13405.1 KHN70318.1 - 0.0016 18.1 0.0 1.6 8.7 0.0 3.7 3 1 1 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 KHN70318.1 - 0.0029 16.7 0.0 2.4 7.6 0.0 2.9 2 1 1 3 3 3 2 EF hand Lip_prot_lig_C PF10437.4 KHN70318.1 - 0.013 15.1 0.2 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Leo1 PF04004.8 KHN70319.1 - 0.062 13.0 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Leo1-like protein S1 PF00575.18 KHN70320.1 - 0.00019 21.4 0.7 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain Ribosomal_S3_C PF00189.15 KHN70321.1 - 2.5e-17 62.8 7.6 5.6e-17 61.7 5.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KHN70321.1 - 0.0067 15.9 0.4 0.015 14.8 0.3 1.6 1 0 0 1 1 1 1 KH domain RIO1 PF01163.17 KHN70322.1 - 9.6e-32 109.8 0.3 1.4e-31 109.2 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KHN70322.1 - 3.5e-13 49.4 0.0 6.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal Pkinase PF00069.20 KHN70322.1 - 9e-06 25.0 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KHN70322.1 - 0.00099 18.9 0.5 0.0048 16.6 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KHN70322.1 - 0.032 13.2 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HU-DNA_bdg PF14848.1 KHN70322.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA-binding domain Ribosomal_S28e PF01200.13 KHN70324.1 - 4.3e-23 80.8 0.9 4.5e-23 80.7 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Frigida PF07899.6 KHN70325.1 - 0.0022 16.7 0.4 0.003 16.3 0.3 1.2 1 0 0 1 1 1 1 Frigida-like protein CARD PF00619.16 KHN70325.1 - 0.045 13.6 0.3 0.1 12.4 0.2 1.6 1 0 0 1 1 1 0 Caspase recruitment domain Utp11 PF03998.8 KHN70326.1 - 9.4e-09 35.4 12.6 1.8e-08 34.5 8.8 1.5 1 1 0 1 1 1 1 Utp11 protein DUF4140 PF13600.1 KHN70326.1 - 0.083 13.3 0.3 35 4.9 0.0 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Hyaluronidase_1 PF07212.6 KHN70326.1 - 0.12 11.3 0.7 0.21 10.5 0.0 1.8 2 1 1 3 3 3 0 Hyaluronidase protein (HylP) Prefoldin_2 PF01920.15 KHN70326.1 - 0.32 10.7 10.1 0.49 10.1 0.0 3.2 3 0 0 3 3 3 0 Prefoldin subunit COG2 PF06148.6 KHN70326.1 - 0.36 10.6 3.0 1.3 8.8 0.3 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tektin PF03148.9 KHN70326.1 - 3.4 6.1 8.3 2.1 6.7 0.7 2.6 2 1 0 2 2 2 0 Tektin family Snf7 PF03357.16 KHN70326.1 - 4.8 6.5 10.4 5.9 6.2 0.1 2.9 3 0 0 3 3 3 0 Snf7 zf-Nse PF11789.3 KHN70327.1 - 1.7e-08 33.8 0.7 4.3e-08 32.5 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 KHN70327.1 - 0.39 10.6 3.4 0.69 9.8 0.6 2.6 1 1 1 2 2 2 0 IBR domain zf-H2C2_2 PF13465.1 KHN70327.1 - 1.8 9.0 4.2 3.4 8.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain MOZ_SAS PF01853.13 KHN70328.1 - 4.5e-43 146.6 0.5 6.2e-43 146.2 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 KHN70328.1 - 0.025 14.7 0.0 0.071 13.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_19 PF00182.14 KHN70329.1 - 7.7e-19 68.2 0.3 5.4e-17 62.2 0.2 2.8 1 1 0 1 1 1 1 Chitinase class I GILT PF03227.11 KHN70329.1 - 0.099 12.5 1.8 0.3 10.9 1.3 1.8 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) CDC45 PF02724.9 KHN70329.1 - 0.41 8.6 14.2 0.78 7.6 9.9 1.4 1 0 0 1 1 1 0 CDC45-like protein DNA_pol3_delta2 PF13177.1 KHN70330.1 - 1.6e-18 66.8 0.1 1.4e-12 47.5 0.1 2.7 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.24 KHN70330.1 - 3.4e-15 56.4 0.1 8.1e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KHN70330.1 - 1.8e-10 40.6 0.0 9.8e-10 38.2 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 KHN70330.1 - 1.5e-08 34.8 4.1 2.9e-05 24.1 2.8 3.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KHN70330.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KHN70330.1 - 3e-07 29.7 0.0 7.2e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_gamma3 PF12169.3 KHN70330.1 - 5.5e-07 29.4 0.0 7.5e-05 22.5 0.0 2.4 1 1 1 2 2 2 1 DNA polymerase III subunits gamma and tau domain III Sigma54_activ_2 PF14532.1 KHN70330.1 - 9.6e-07 28.9 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 KHN70330.1 - 1.1e-06 29.4 0.0 4.3e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KHN70330.1 - 1.9e-06 26.8 1.1 0.00097 17.9 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 KHN70330.1 - 6.6e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 KHN70330.1 - 8.3e-06 25.5 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KHN70330.1 - 2.2e-05 23.7 0.0 0.00012 21.3 0.0 1.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KHN70330.1 - 3.1e-05 23.6 0.1 6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KHN70330.1 - 3.3e-05 23.9 0.0 0.00015 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.6 KHN70330.1 - 5.1e-05 22.8 0.0 9.2e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 KHN70330.1 - 8.2e-05 21.9 0.1 0.00027 20.2 0.1 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 KHN70330.1 - 0.00011 22.4 0.0 0.00022 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KHN70330.1 - 0.00014 21.4 0.0 0.00035 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain DEAD PF00270.24 KHN70330.1 - 0.00026 20.5 0.5 0.043 13.3 0.1 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 KHN70330.1 - 0.00039 20.1 1.6 0.033 13.8 0.1 2.6 1 1 2 3 3 3 1 NTPase AAA_5 PF07728.9 KHN70330.1 - 0.00063 19.4 0.2 0.0037 16.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KHN70330.1 - 0.0009 18.8 0.1 0.0067 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KHN70330.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 KHN70330.1 - 0.0016 18.2 0.3 0.0041 16.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KHN70330.1 - 0.0031 17.0 0.0 0.007 15.8 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_28 PF13521.1 KHN70330.1 - 0.0033 17.4 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KHN70330.1 - 0.0035 17.0 0.0 0.094 12.3 0.0 2.3 1 1 1 2 2 2 1 NACHT domain DNA_pol3_delta PF06144.8 KHN70330.1 - 0.0035 16.8 0.2 0.0079 15.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit PhoH PF02562.11 KHN70330.1 - 0.0044 16.2 0.1 0.91 8.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein ABC_tran PF00005.22 KHN70330.1 - 0.0047 17.2 0.0 0.016 15.5 0.0 2.1 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.8 KHN70330.1 - 0.005 15.6 0.1 0.22 10.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_11 PF13086.1 KHN70330.1 - 0.0073 15.9 0.7 0.079 12.5 0.3 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KHN70330.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 KHN70330.1 - 0.014 14.4 0.4 0.28 10.1 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KHN70330.1 - 0.017 14.6 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 KHN70330.1 - 0.017 14.5 0.3 0.064 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KHN70330.1 - 0.023 14.5 0.1 0.063 13.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 KHN70330.1 - 0.035 12.7 0.0 0.06 11.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.12 KHN70330.1 - 0.036 13.4 0.1 0.1 11.9 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 KHN70330.1 - 0.045 13.6 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) T2SE PF00437.15 KHN70330.1 - 0.053 12.4 0.0 0.13 11.0 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 KHN70330.1 - 0.1 12.0 0.3 0.28 10.5 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain APS_kinase PF01583.15 KHN70330.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Parvo_NS1 PF01057.12 KHN70330.1 - 0.11 11.3 0.1 0.58 8.9 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KHN70331.1 - 0.0017 18.4 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 KHN70331.1 - 0.0035 17.0 0.2 0.0039 16.8 0.2 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KHN70331.1 - 0.0065 17.2 0.0 0.008 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KHN70331.1 - 0.0076 16.5 0.1 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 KHN70331.1 - 0.0086 15.9 0.1 0.019 14.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KHN70331.1 - 0.0099 16.0 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KHN70331.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KHN70331.1 - 0.014 15.3 0.1 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KHN70331.1 - 0.016 15.5 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KHN70331.1 - 0.017 15.0 0.1 0.019 14.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KHN70331.1 - 0.047 13.2 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.17 KHN70331.1 - 0.05 13.0 0.2 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KHN70331.1 - 0.052 13.2 0.1 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 KHN70331.1 - 0.053 13.0 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KHN70331.1 - 0.054 12.3 0.1 0.066 12.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF927 PF06048.6 KHN70331.1 - 0.072 12.3 0.2 0.09 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) MMR_HSR1 PF01926.18 KHN70331.1 - 0.096 12.6 0.2 0.1 12.5 0.1 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 KHN70331.1 - 0.13 11.4 0.1 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S8 PF00410.14 KHN70332.1 - 3.8e-21 75.2 0.0 6.5e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 MCM PF00493.18 KHN70333.1 - 6.8e-120 399.8 0.3 9.5e-120 399.3 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KHN70333.1 - 2.6e-16 60.1 0.6 8.8e-16 58.4 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KHN70333.1 - 2.5e-07 30.0 0.2 1.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KHN70333.1 - 1.6e-06 27.8 0.0 5.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KHN70333.1 - 0.00077 19.0 0.0 0.0019 17.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KHN70333.1 - 0.0071 15.8 0.1 0.054 12.9 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-UDP PF14569.1 KHN70333.1 - 0.012 15.3 0.3 0.029 14.0 0.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger GCC2_GCC3 PF07699.8 KHN70333.1 - 0.079 12.5 0.7 0.2 11.2 0.5 1.6 1 0 0 1 1 1 0 GCC2 and GCC3 DZF PF07528.9 KHN70333.1 - 0.086 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 DZF domain HAS-barrel PF09378.5 KHN70334.1 - 0.00031 20.5 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 HAS barrel domain Peptidase_A4 PF01828.12 KHN70334.1 - 0.51 9.3 2.3 5 6.1 0.1 2.1 2 0 0 2 2 2 0 Peptidase A4 family Glutaredoxin PF00462.19 KHN70335.1 - 7.9e-12 44.9 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KHN70335.1 - 0.045 13.9 0.1 0.12 12.5 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 KHN70335.1 - 0.11 12.7 0.1 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) NMD3 PF04981.8 KHN70336.1 - 7.4e-59 198.7 7.9 7.4e-59 198.7 5.5 1.8 2 0 0 2 2 2 1 NMD3 family DZR PF12773.2 KHN70336.1 - 2.2 8.1 7.4 1.1 9.1 2.8 2.2 2 0 0 2 2 2 0 Double zinc ribbon TIP49 PF06068.8 KHN70337.1 - 2.3e-164 546.8 2.9 2.6e-164 546.6 2.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KHN70337.1 - 9.4e-10 38.8 0.4 3.4e-05 24.0 0.1 2.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KHN70337.1 - 6.2e-07 28.6 0.2 6.8e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KHN70337.1 - 1.7e-05 24.9 0.0 0.035 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KHN70337.1 - 0.00017 21.6 0.0 0.086 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 KHN70337.1 - 0.0004 20.3 0.0 0.37 10.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KHN70337.1 - 0.0005 19.7 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 KHN70337.1 - 0.0027 17.3 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activat PF00158.21 KHN70337.1 - 0.0073 15.7 0.1 3.2 7.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain UPF0079 PF02367.12 KHN70337.1 - 0.017 14.7 0.1 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 KHN70337.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 KHN70337.1 - 0.026 13.6 0.2 0.74 8.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 KHN70337.1 - 0.066 12.8 2.5 0.17 11.5 0.3 2.6 2 1 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 KHN70337.1 - 0.073 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DBI_PRT PF02277.12 KHN70337.1 - 0.077 12.0 0.3 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase Sigma54_activ_2 PF14532.1 KHN70337.1 - 0.12 12.3 0.0 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 KHN70337.1 - 0.13 11.6 0.0 0.62 9.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KHN70337.1 - 0.24 12.2 1.2 1.3 9.8 0.5 2.6 2 1 0 2 2 1 0 AAA domain RhoGAP PF00620.22 KHN70338.1 - 1.5e-10 40.9 2.4 9.6e-10 38.2 0.2 2.3 2 1 0 2 2 2 1 RhoGAP domain DUF2603 PF10788.4 KHN70338.1 - 0.086 12.5 1.5 0.16 11.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) RRM_5 PF13893.1 KHN70339.1 - 0.00021 21.0 0.3 0.0011 18.7 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KHN70339.1 - 0.00033 20.2 3.2 0.00033 20.2 2.2 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Hydrolase PF00702.21 KHN70340.1 - 2.8e-15 57.3 0.0 4.8e-14 53.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KHN70340.1 - 2.2e-12 46.4 0.7 2.2e-12 46.4 0.5 3.2 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 KHN70340.1 - 3.2e-12 47.0 0.1 9.6e-12 45.4 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KHN70340.1 - 3.7e-07 30.0 0.0 2.4e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hemolysin_N PF12563.3 KHN70340.1 - 0.0029 17.0 0.1 0.0081 15.6 0.0 1.7 1 0 0 1 1 1 1 Hemolytic toxin N terminal Ras PF00071.17 KHN70341.1 - 3.7e-50 169.4 0.9 4.3e-50 169.2 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KHN70341.1 - 1.1e-22 80.8 0.1 1.7e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KHN70341.1 - 3.2e-19 68.8 0.2 3.6e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN70341.1 - 6.4e-11 41.8 0.2 7.7e-11 41.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KHN70341.1 - 5.8e-10 38.9 0.2 1.3e-08 34.4 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KHN70341.1 - 5.6e-07 29.5 0.2 1e-06 28.6 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KHN70341.1 - 1.6e-05 24.1 0.1 2e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KHN70341.1 - 0.0012 18.9 0.1 0.0043 17.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain YTH PF04146.10 KHN70341.1 - 0.0048 16.4 0.1 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain FeoB_N PF02421.13 KHN70341.1 - 0.093 11.9 0.0 2.3 7.4 0.0 2.7 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF1471 PF07338.8 KHN70341.1 - 0.11 12.1 0.3 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) Rgp1 PF08737.5 KHN70341.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Rgp1 WD40 PF00400.27 KHN70342.1 - 3.5e-06 26.6 0.3 0.00023 20.9 0.0 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KHN70342.1 - 0.00033 19.5 0.1 0.00048 18.9 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KHN70342.1 - 0.014 13.6 0.3 0.033 12.4 0.0 1.8 3 0 0 3 3 3 0 Cytochrome D1 heme domain RRM_6 PF14259.1 KHN70343.1 - 1.7e-10 40.7 0.0 0.00046 20.1 0.0 2.7 2 2 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN70343.1 - 7.4e-09 35.1 0.1 0.0013 18.3 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70343.1 - 6.3e-05 22.7 0.1 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4247 PF14042.1 KHN70343.1 - 0.09 12.7 0.1 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) WD40 PF00400.27 KHN70344.1 - 7.8e-18 63.6 6.2 0.00091 19.0 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat HEAT_2 PF13646.1 KHN70345.1 - 1.2e-15 57.5 0.2 0.006 16.8 0.0 5.3 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.17 KHN70345.1 - 1.1e-12 46.8 2.3 2.1 8.6 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 KHN70345.1 - 0.0011 19.4 0.1 4 8.0 0.0 4.0 3 0 0 3 3 3 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KHN70345.1 - 0.0058 16.5 1.4 2 8.4 0.2 3.2 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion DNA_alkylation PF08713.6 KHN70345.1 - 0.0099 15.4 0.3 0.07 12.6 0.0 2.4 1 1 1 2 2 2 1 DNA alkylation repair enzyme Methyltransf_11 PF08241.7 KHN70346.1 - 3.6e-15 56.2 0.4 8.6e-15 55.0 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KHN70346.1 - 9.5e-12 44.9 0.0 2e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN70346.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KHN70346.1 - 3.4e-08 33.7 0.1 7.5e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KHN70346.1 - 2e-06 28.1 0.5 1.6e-05 25.3 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KHN70346.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KHN70346.1 - 0.0023 18.4 0.4 0.084 13.4 0.3 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KHN70346.1 - 0.0062 16.5 0.2 0.099 12.6 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KHN70346.1 - 0.029 13.4 0.0 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 KHN70346.1 - 0.065 12.4 0.2 0.86 8.7 0.1 2.2 1 1 0 1 1 1 0 Tellurite resistance protein TehB Pox_MCEL PF03291.11 KHN70346.1 - 0.11 11.3 0.0 0.51 9.1 0.0 1.9 2 1 0 2 2 2 0 mRNA capping enzyme DUF367 PF04034.8 KHN70348.1 - 1.9e-49 166.5 0.0 2.4e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KHN70348.1 - 9.7e-10 37.8 1.4 9.7e-10 37.8 1.0 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI Metallothio_2 PF01439.13 KHN70349.1 - 8.6 6.9 7.3 1 9.9 1.2 2.3 2 1 0 2 2 2 0 Metallothionein WaaY PF06176.6 KHN70351.1 - 0.0084 15.3 0.2 0.011 15.0 0.2 1.2 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Acetyltransf_8 PF13523.1 KHN70353.1 - 0.014 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NotI PF12183.3 KHN70353.1 - 0.028 13.4 0.3 0.037 13.1 0.2 1.1 1 0 0 1 1 1 0 Restriction endonuclease NotI DUF3567 PF12091.3 KHN70354.1 - 0.035 14.0 0.1 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3567) HMG_box_5 PF14887.1 KHN70354.1 - 0.28 10.9 4.2 0.29 10.9 0.5 2.7 2 1 1 3 3 3 0 HMG (high mobility group) box 5 TctB PF07331.6 KHN70354.1 - 2.6 7.7 15.0 0.44 10.1 4.1 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family LRR_4 PF12799.2 KHN70355.1 - 2.8e-11 42.7 4.2 5.8e-07 28.9 0.1 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KHN70355.1 - 2.5e-07 29.8 11.7 0.41 10.8 0.1 5.1 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_8 PF13855.1 KHN70355.1 - 1.7e-06 27.6 8.5 0.00013 21.6 1.3 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 KHN70355.1 - 2e-05 24.0 2.5 18 6.0 0.0 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 KHN70355.1 - 4.9e-05 22.9 13.4 3 8.2 0.3 5.1 3 1 2 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 KHN70356.1 - 0.00035 20.1 0.0 0.015 14.9 0.0 2.4 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KHN70356.1 - 0.0013 18.4 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_8 PF13855.1 KHN70356.1 - 0.0018 17.9 0.2 0.35 10.6 0.0 2.6 3 0 0 3 3 3 2 Leucine rich repeat DNA_III_psi PF03603.8 KHN70356.1 - 0.027 14.3 0.1 0.066 13.0 0.0 1.6 1 1 0 1 1 1 0 DNA polymerase III psi subunit AzlD PF05437.7 KHN70357.1 - 0.009 15.9 0.2 0.009 15.9 0.1 2.7 2 2 2 4 4 4 1 Branched-chain amino acid transport protein (AzlD) DUF420 PF04238.7 KHN70357.1 - 1.2 9.0 17.9 1.9 8.4 6.0 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF420) UBX PF00789.15 KHN70358.1 - 0.0021 18.0 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Pex14_N PF04695.8 KHN70358.1 - 0.018 15.1 3.2 0.022 14.7 2.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UBA PF00627.26 KHN70358.1 - 0.019 14.7 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Cnd1 PF12717.2 KHN70358.1 - 0.082 12.7 1.0 0.094 12.5 0.7 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HNF-1_N PF04814.8 KHN70358.1 - 0.13 12.3 5.3 0.53 10.3 3.7 1.8 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RE_HindIII PF09518.5 KHN70358.1 - 0.16 10.8 7.3 5.8 5.7 0.0 2.3 1 1 2 3 3 3 0 HindIII restriction endonuclease Thg1C PF14413.1 KHN70358.1 - 0.18 11.4 3.7 0.47 10.1 2.1 2.1 2 1 0 2 2 2 0 Thg1 C terminal domain Glycolytic PF00274.14 KHN70359.1 - 2.3e-106 355.1 0.0 2.8e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF866 PF05907.8 KHN70360.1 - 2.8e-08 33.4 6.2 4.1e-07 29.6 4.3 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) HSP33 PF01430.14 KHN70360.1 - 0.013 14.6 1.8 0.018 14.2 1.2 1.2 1 0 0 1 1 1 0 Hsp33 protein Dynein_light PF01221.13 KHN70361.1 - 3.4e-10 39.7 0.1 5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Pentapeptide_3 PF13576.1 KHN70361.1 - 0.055 13.3 1.8 0.073 12.9 0.2 2.0 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) ICAM_N PF03921.9 KHN70362.1 - 0.14 11.6 1.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain zf-C2H2_jaz PF12171.3 KHN70363.1 - 3e-05 24.0 1.8 5.4e-05 23.1 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KHN70363.1 - 0.002 18.2 3.1 0.0031 17.6 2.0 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KHN70363.1 - 0.0025 17.9 1.1 0.0063 16.6 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 KHN70363.1 - 0.024 14.3 0.2 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger DUF2315 PF10231.4 KHN70363.1 - 0.076 12.8 1.9 0.11 12.3 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) DUF4441 PF14536.1 KHN70363.1 - 0.17 11.8 5.0 0.25 11.3 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) SNARE PF05739.14 KHN70364.1 - 2.1e-05 24.1 1.7 2.9e-05 23.6 1.2 1.2 1 0 0 1 1 1 1 SNARE domain Rab5ip PF07019.7 KHN70364.1 - 0.022 14.8 0.5 0.031 14.3 0.4 1.2 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Spore_YhaL PF14147.1 KHN70364.1 - 0.63 9.5 7.1 2 7.9 1.1 2.8 3 0 0 3 3 3 0 Sporulation protein YhaL Ribosomal_L2_C PF03947.13 KHN70365.1 - 3.4e-33 114.1 1.7 5.2e-33 113.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KHN70365.1 - 2.5e-06 27.3 0.1 8.1e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Mpp10 PF04006.7 KHN70367.1 - 5.2e-12 44.9 3.1 5.2e-12 44.9 2.1 1.4 1 1 0 1 1 1 1 Mpp10 protein NIF PF03031.13 KHN70368.1 - 1e-15 57.7 0.2 1.2e-15 57.4 0.2 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KHN70368.1 - 5.4e-05 23.4 0.1 0.12 12.5 0.1 2.4 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KHN70368.1 - 0.0053 16.6 0.0 0.061 13.2 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KHN70368.1 - 0.11 12.0 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase SNF2_N PF00176.18 KHN70369.1 - 6.9e-69 231.9 0.2 1.2e-68 231.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KHN70369.1 - 2.5e-16 59.2 0.0 1.3e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 KHN70369.1 - 1.1e-14 53.8 3.8 3.3e-09 36.2 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 KHN70369.1 - 1.9e-08 34.3 0.1 6.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KHN70369.1 - 1.4e-05 24.6 0.0 3.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AT_hook PF02178.14 KHN70369.1 - 0.14 11.9 5.3 0.38 10.5 3.7 1.8 1 0 0 1 1 1 0 AT hook motif Brix PF04427.13 KHN70370.1 - 1.6e-18 67.0 0.1 1.9e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Brix domain DnaJ PF00226.26 KHN70371.1 - 0.00068 19.3 0.0 0.0023 17.6 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-bind_5 PF13873.1 KHN70371.1 - 0.0048 16.7 3.2 0.012 15.4 0.5 2.4 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain CobW_C PF07683.9 KHN70371.1 - 0.052 13.2 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Rcd1 PF04078.8 KHN70372.1 - 7.5e-50 169.2 0.4 9.4e-50 168.8 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like PRP38 PF03371.10 KHN70372.1 - 0.0053 16.3 0.2 2.8 7.5 0.0 2.5 2 1 0 2 2 2 2 PRP38 family FIIND PF13553.1 KHN70372.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Function to find DUF3893 PF13032.1 KHN70372.1 - 0.037 14.1 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3893) MMS19_C PF12460.3 KHN70372.1 - 0.12 11.1 2.3 0.08 11.6 0.3 1.6 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Choline_transpo PF04515.7 KHN70374.1 - 8.3e-14 51.0 35.8 5.7e-13 48.3 24.8 2.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter DUF3450 PF11932.3 KHN70375.1 - 0.017 14.4 1.2 0.017 14.4 0.8 4.1 3 1 1 5 5 5 0 Protein of unknown function (DUF3450) SlyX PF04102.7 KHN70375.1 - 5.9 7.3 14.1 1.1 9.6 0.0 4.6 4 1 0 4 4 4 0 SlyX PspB PF06667.7 KHN70375.1 - 9.7 6.2 13.6 12 5.8 0.8 4.4 4 0 0 4 4 4 0 Phage shock protein B BAR_2 PF10455.4 KHN70376.1 - 5.5e-05 22.2 11.8 0.00011 21.2 8.2 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Hrs_helical PF12210.3 KHN70376.1 - 0.068 13.4 2.9 4.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate PMC2NT PF08066.7 KHN70376.1 - 0.087 13.1 3.0 0.12 12.7 0.6 2.3 2 1 0 2 2 2 0 PMC2NT (NUC016) domain TMPIT PF07851.8 KHN70376.1 - 0.3 10.1 4.2 0.53 9.2 2.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein Pet20 PF08692.5 KHN70376.1 - 0.94 9.4 4.9 0.81 9.6 0.2 2.6 2 1 1 3 3 3 0 Mitochondrial protein Pet20 DUF2758 PF10957.3 KHN70376.1 - 8.8 6.2 9.6 2 8.2 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2758) zf-CCCH PF00642.19 KHN70377.1 - 5.2e-09 35.5 37.7 3.1e-05 23.5 0.3 5.0 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sporozoite_P67 PF05642.6 KHN70378.1 - 0.0029 15.5 2.0 0.0042 15.0 1.4 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen BHD_1 PF10403.4 KHN70379.1 - 2.1e-13 49.5 0.3 6.9e-13 47.9 0.1 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 KHN70379.1 - 0.023 14.4 0.1 0.064 12.9 0.0 1.8 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 Actin PF00022.14 KHN70380.1 - 6.9e-154 512.0 0.0 7.8e-154 511.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KHN70380.1 - 0.046 14.1 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fork_head PF00250.13 KHN70381.1 - 3.5e-32 110.2 0.8 5.9e-32 109.5 0.5 1.3 1 0 0 1 1 1 1 Fork head domain EMG1 PF03587.9 KHN70382.1 - 1.1e-29 103.1 0.3 1.4e-29 102.8 0.2 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DegS PF05384.6 KHN70383.1 - 0.087 12.0 2.6 0.082 12.1 1.0 1.5 1 1 1 2 2 2 0 Sensor protein DegS s48_45 PF07422.8 KHN70383.1 - 0.092 12.8 1.9 0.24 11.5 1.3 1.6 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain Syntaxin-6_N PF09177.6 KHN70383.1 - 0.098 13.0 0.6 0.17 12.3 0.3 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF2205 PF10224.4 KHN70383.1 - 0.12 11.9 0.6 0.26 10.8 0.1 1.9 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Snf7 PF03357.16 KHN70383.1 - 1.2 8.4 7.3 0.94 8.8 0.8 2.1 1 1 1 2 2 2 0 Snf7 Med6 PF04934.9 KHN70384.1 - 8.3e-35 119.3 3.0 1.1e-34 118.9 2.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component NifU_N PF01592.11 KHN70385.1 - 6.3e-51 171.6 0.0 7e-51 171.4 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain DUF3671 PF12420.3 KHN70387.1 - 0.28 11.1 2.2 0.38 10.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function GRASP55_65 PF04495.9 KHN70388.1 - 1.7e-23 83.1 0.4 2e-19 69.9 0.1 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KHN70388.1 - 0.0015 18.3 0.0 0.0085 15.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 KHN70388.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) RRM_1 PF00076.17 KHN70389.1 - 1.8e-12 46.6 0.0 3.1e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KHN70389.1 - 2.6e-11 43.3 0.1 8.1e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70389.1 - 5.6e-07 29.3 0.2 1.8e-06 27.6 0.0 1.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KHN70389.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif LSM PF01423.17 KHN70390.1 - 1.6e-12 46.7 0.3 2.4e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF3139 PF11337.3 KHN70391.1 - 0.052 13.8 0.1 0.052 13.8 0.1 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3139) Wzy_C PF04932.10 KHN70391.1 - 4.9 6.9 12.3 24 4.6 8.5 2.3 1 1 0 1 1 1 0 O-Antigen ligase GAS PF13851.1 KHN70393.1 - 1.7e-05 24.1 20.2 1.7e-05 24.1 14.0 5.8 3 1 2 5 5 5 1 Growth-arrest specific micro-tubule binding Microtub_assoc PF07989.6 KHN70393.1 - 0.00058 19.6 4.9 0.00058 19.6 3.4 6.8 5 2 2 7 7 7 2 Microtubule associated Shugoshin_N PF07558.6 KHN70393.1 - 0.0016 18.1 1.3 0.0016 18.1 0.9 4.8 5 0 0 5 5 5 1 Shugoshin N-terminal coiled-coil region Filament PF00038.16 KHN70393.1 - 0.0018 17.8 11.6 0.0018 17.8 8.0 4.5 1 1 3 4 4 4 2 Intermediate filament protein TMF_DNA_bd PF12329.3 KHN70393.1 - 0.02 14.7 2.0 0.02 14.7 1.4 9.3 6 2 3 9 9 9 0 TATA element modulatory factor 1 DNA binding CCDC92 PF14916.1 KHN70393.1 - 1.9 8.1 19.3 0.33 10.5 0.5 4.9 4 1 0 4 4 4 0 Coiled-coil domain of unknown function MbeD_MobD PF04899.7 KHN70393.1 - 2.5 8.0 8.1 1.1 9.1 0.1 4.3 3 2 3 6 6 6 0 MbeD/MobD like DUF904 PF06005.7 KHN70393.1 - 2.6 8.3 71.4 0.6 10.4 2.3 8.7 5 2 3 8 8 8 0 Protein of unknown function (DUF904) IncA PF04156.9 KHN70393.1 - 8.4 5.9 61.5 3.2 7.3 4.2 5.8 2 1 3 5 5 5 0 IncA protein DnaJ PF00226.26 KHN70394.1 - 6.9e-14 51.3 0.2 6.9e-14 51.3 0.1 2.2 2 1 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 KHN70394.1 - 1.3e-05 25.1 3.5 1.3e-05 25.1 2.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KHN70394.1 - 0.0014 18.7 7.2 0.005 16.9 5.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KHN70394.1 - 0.023 14.7 5.0 0.14 12.2 0.9 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 KHN70394.1 - 0.13 12.6 8.1 3.6 8.1 2.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Dynein_light PF01221.13 KHN70395.1 - 0.83 9.6 3.8 13 5.8 0.0 2.8 2 1 1 3 3 3 0 Dynein light chain type 1 RNA_pol_A_bac PF01000.21 KHN70397.1 - 4.4e-20 71.9 0.1 1.7e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KHN70397.1 - 2e-12 46.0 0.0 2.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KHN70398.1 - 2e-35 119.4 16.5 2e-07 30.6 0.1 9.5 10 0 0 10 10 10 7 WD domain, G-beta repeat CTD_bind PF04818.8 KHN70399.1 - 3.5e-07 30.3 0.4 8.5e-07 29.1 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Pkinase PF00069.20 KHN70400.1 - 7.7e-67 225.1 0.1 9.7e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70400.1 - 5.3e-41 140.4 0.0 7e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KHN70400.1 - 4.6e-09 36.1 0.0 1.5e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 POLO box duplicated region Kinase-like PF14531.1 KHN70400.1 - 6.3e-09 35.2 0.0 2.3e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KHN70400.1 - 0.0025 17.5 0.0 0.039 13.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KHN70400.1 - 0.0061 15.9 0.6 0.21 10.9 0.1 2.3 1 1 1 2 2 2 1 RIO1 family Carbpep_Y_N PF05388.6 KHN70401.1 - 0.028 14.5 1.3 0.25 11.5 0.0 2.8 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF3199 PF11436.3 KHN70401.1 - 0.031 14.1 0.3 0.069 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Exonuc_VII_S PF02609.11 KHN70401.1 - 0.035 13.8 1.2 0.14 11.9 0.8 2.1 1 0 0 1 1 1 0 Exonuclease VII small subunit PGM_PMM_I PF02878.11 KHN70402.1 - 2.3e-19 69.2 1.3 8.7e-09 34.9 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KHN70402.1 - 1.2e-15 57.7 0.0 4.7e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KHN70402.1 - 4.3e-08 33.0 0.0 1.2e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KHN70402.1 - 0.0025 17.8 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Tfb2 PF03849.9 KHN70403.1 - 1.2e-43 149.1 6.3 6.5e-42 143.4 4.4 2.2 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KHN70403.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_redox_2 PF07992.9 KHN70404.1 - 0.00089 19.1 0.1 0.00096 19.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KHN70404.1 - 0.0096 14.8 0.0 0.015 14.2 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KHN70404.1 - 0.03 12.9 0.1 1.2 7.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GTP_EFTU PF00009.22 KHN70406.1 - 2e-39 134.9 0.1 3.5e-39 134.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KHN70406.1 - 1.1e-25 89.4 1.1 5.2e-25 87.3 0.1 2.4 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KHN70406.1 - 7.4e-09 35.5 0.2 2.7e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KHN70406.1 - 0.00032 20.6 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1319 PF07028.6 KHN70407.1 - 0.0048 17.0 2.3 0.0057 16.8 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1319) Thioredoxin PF00085.15 KHN70408.1 - 1.8e-06 27.5 0.1 2.6e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KHN70408.1 - 8.6e-05 21.3 1.0 0.00064 18.5 0.7 1.9 1 1 0 1 1 1 1 Phosducin DIM1 PF02966.11 KHN70408.1 - 0.01 15.3 0.4 0.016 14.7 0.2 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 PRK PF00485.13 KHN70409.1 - 6.8e-08 32.2 0.4 3.8e-07 29.8 0.1 2.2 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KHN70409.1 - 1.1e-05 26.2 0.0 2.6e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KHN70409.1 - 0.00013 22.2 0.1 0.00041 20.6 0.0 2.1 2 1 0 2 2 1 1 AAA domain KTI12 PF08433.5 KHN70409.1 - 0.0026 17.0 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 T2SE PF00437.15 KHN70409.1 - 0.0082 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 KHN70409.1 - 0.014 15.7 0.8 0.019 15.2 0.5 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KHN70409.1 - 0.034 14.0 0.1 0.1 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KHN70409.1 - 0.039 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 KHN70409.1 - 0.048 13.1 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CPT PF07931.7 KHN70409.1 - 0.06 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.7 KHN70409.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 KHN70409.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KHN70409.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KHN70409.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KHN70409.1 - 0.19 11.6 10.1 0.35 10.8 7.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KHN70409.1 - 0.19 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Gate PF07670.9 KHN70410.1 - 0.028 14.3 2.3 0.038 13.8 1.6 1.1 1 0 0 1 1 1 0 Nucleoside recognition SecD_SecF PF02355.11 KHN70410.1 - 0.056 12.6 0.3 0.063 12.4 0.2 1.0 1 0 0 1 1 1 0 Protein export membrane protein TK PF00265.13 KHN70411.1 - 3.2e-38 131.0 0.1 3.9e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_30 PF13604.1 KHN70411.1 - 0.00021 20.9 0.0 0.00061 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain IMPDH PF00478.20 KHN70411.1 - 0.032 13.1 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain AAA_22 PF13401.1 KHN70411.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 KHN70412.1 - 4.4e-11 42.4 10.4 4.4e-11 42.4 7.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KHN70412.1 - 3.7e-07 29.7 6.4 3.7e-07 29.7 4.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KHN70412.1 - 2.9e-05 23.9 11.6 2.9e-05 23.9 8.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KHN70412.1 - 0.00019 21.4 13.2 0.00019 21.4 9.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KHN70412.1 - 0.00025 20.6 10.4 0.00061 19.3 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1600 PF07667.6 KHN70412.1 - 0.0039 17.2 2.2 0.0039 17.2 1.5 3.3 2 1 2 4 4 4 1 Protein of unknown function (DUF1600) zf-RING_5 PF14634.1 KHN70412.1 - 0.0069 16.0 11.3 0.02 14.5 7.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KHN70412.1 - 0.23 11.3 9.2 1 9.2 6.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sdh_cyt PF01127.17 KHN70412.1 - 0.45 10.3 11.9 0.37 10.6 1.2 2.5 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit zf-RING_UBOX PF13445.1 KHN70412.1 - 2.4 7.9 10.0 0.17 11.6 1.9 2.7 2 1 1 3 3 3 0 RING-type zinc-finger RecR PF02132.10 KHN70412.1 - 2.5 7.6 5.9 6.7 6.2 0.4 2.5 2 0 0 2 2 2 0 RecR protein zf-C3HC4_4 PF15227.1 KHN70412.1 - 2.7 7.9 20.9 0.038 13.8 6.8 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Myb_DNA-binding PF00249.26 KHN70413.1 - 5.1e-08 32.8 0.1 5e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KHN70413.1 - 8.1e-06 25.8 0.2 3e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain MCRS_N PF13325.1 KHN70413.1 - 0.0085 15.6 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Tcf25 PF04910.9 KHN70413.1 - 0.012 14.6 0.8 0.016 14.2 0.6 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Ring_hydroxyl_A PF00848.14 KHN70413.1 - 0.048 13.3 0.4 0.05 13.2 0.2 1.3 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) zf-C2H2_4 PF13894.1 KHN70414.1 - 0.0028 17.8 4.0 0.027 14.7 1.5 6.1 5 2 1 6 6 6 3 C2H2-type zinc finger Glyco_transf_20 PF00982.16 KHN70416.1 - 1e-134 449.5 0.4 2.3e-134 448.4 0.3 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 KHN70416.1 - 0.00028 20.4 0.9 0.0098 15.4 0.3 2.4 2 0 0 2 2 2 1 Starch synthase catalytic domain DUF3747 PF12565.3 KHN70416.1 - 0.08 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) DUF1240 PF06836.7 KHN70417.1 - 2.6 8.3 8.5 0.31 11.3 2.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1240) ATP1G1_PLM_MAT8 PF02038.11 KHN70418.1 - 0.042 12.8 1.1 0.075 12.0 0.1 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family zf-CCCH PF00642.19 KHN70419.1 - 2.1e-19 68.7 16.0 2.1e-10 40.0 2.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KHN70419.1 - 0.0036 17.2 1.0 0.0036 17.2 0.7 3.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type ARD PF03079.9 KHN70419.1 - 0.0062 16.4 0.8 0.016 15.1 0.6 1.7 1 0 0 1 1 1 1 ARD/ARD' family N6_Mtase PF02384.11 KHN70419.1 - 0.015 14.3 0.3 0.022 13.8 0.2 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase RRM_6 PF14259.1 KHN70420.1 - 5e-10 39.2 0.1 3.7e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KHN70420.1 - 2.9e-09 36.4 0.1 5e-08 32.4 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KHN70420.1 - 5e-05 23.0 0.0 0.00081 19.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 KHN70421.1 - 0.0033 17.6 0.1 0.044 14.1 0.1 2.4 2 0 0 2 2 2 1 PCI domain SICA_beta PF12878.2 KHN70421.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 SICA extracellular beta domain KAT11 PF08214.6 KHN70422.1 - 1e-05 24.7 0.3 0.0022 17.1 0.0 2.3 1 1 1 2 2 2 2 Histone acetylation protein Trehalose_PPase PF02358.11 KHN70423.1 - 1.7e-41 141.7 0.0 2.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_20 PF00982.16 KHN70423.1 - 6e-13 48.0 0.1 9.8e-13 47.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Hydrolase_3 PF08282.7 KHN70423.1 - 0.0062 16.1 0.1 4.7 6.6 0.0 3.0 1 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase EndoU_bacteria PF14436.1 KHN70425.1 - 0.095 12.5 0.9 0.18 11.6 0.3 1.6 1 1 0 1 1 1 0 Bacterial EndoU nuclease Tir_receptor_C PF07489.6 KHN70425.1 - 0.17 11.6 0.2 0.23 11.1 0.2 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus CopK PF11525.3 KHN70427.1 - 1.5 8.5 7.4 7.3 6.3 0.1 2.5 1 1 1 2 2 2 0 Copper resistance protein K Ribosomal_L7Ae PF01248.21 KHN70428.1 - 2.3e-11 43.0 1.5 3.2e-11 42.6 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glutaredoxin PF00462.19 KHN70428.1 - 0.045 13.7 0.1 0.094 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin Hpr_kinase_N PF02603.11 KHN70428.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 HPr Serine kinase N terminus SapB_1 PF05184.10 KHN70428.1 - 0.27 11.1 1.4 0.53 10.1 0.1 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 Thioredoxin PF00085.15 KHN70429.1 - 2.7e-08 33.4 0.5 3.9e-08 32.9 0.3 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KHN70429.1 - 0.00031 20.8 0.1 0.24 11.5 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 KHN70429.1 - 0.005 16.8 0.1 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KHN70429.1 - 0.013 15.7 0.2 0.12 12.5 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain UQ_con PF00179.21 KHN70430.1 - 4.5e-37 126.5 0.3 5.2e-37 126.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KHN70430.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KHN70430.1 - 0.036 13.9 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain DUF2608 PF11019.3 KHN70431.1 - 0.12 11.3 1.1 1.4 7.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) X8 PF07983.8 KHN70431.1 - 0.15 12.5 0.4 0.26 11.8 0.3 1.4 1 0 0 1 1 1 0 X8 domain HTH_3 PF01381.17 KHN70432.1 - 0.0018 18.1 0.3 0.0029 17.3 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix eIF-3c_N PF05470.7 KHN70432.1 - 0.03 12.4 0.5 0.031 12.4 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ribosomal_L28e PF01778.12 KHN70432.1 - 0.11 12.8 0.4 0.15 12.4 0.3 1.2 1 0 0 1 1 1 0 Ribosomal L28e protein family TBPIP PF07106.8 KHN70433.1 - 1.5e-33 115.6 9.1 1.9e-33 115.3 6.3 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 KHN70433.1 - 0.00013 20.6 7.6 0.00017 20.2 5.3 1.1 1 0 0 1 1 1 1 AAA domain Laminin_II PF06009.7 KHN70433.1 - 0.0093 15.7 4.8 0.18 11.5 1.1 2.1 1 1 1 2 2 2 1 Laminin Domain II FlxA PF14282.1 KHN70433.1 - 0.012 15.5 2.6 0.013 15.4 1.1 1.5 1 1 0 1 1 1 0 FlxA-like protein Prefoldin PF02996.12 KHN70433.1 - 0.57 9.8 11.5 3 7.5 0.2 3.4 1 1 2 3 3 3 0 Prefoldin subunit DUF3847 PF12958.2 KHN70433.1 - 0.86 9.4 4.5 1.8 8.3 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) Atg14 PF10186.4 KHN70433.1 - 0.97 8.3 5.5 4.3 6.1 3.8 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 KHN70433.1 - 1.8 8.3 11.5 1.7 8.4 0.9 2.4 1 1 1 2 2 2 0 Tropomyosin like XhlA PF10779.4 KHN70433.1 - 2.2 8.2 9.4 3.9 7.4 0.1 2.5 2 1 0 2 2 2 0 Haemolysin XhlA IncA PF04156.9 KHN70433.1 - 2.3 7.7 9.4 15 5.1 6.5 2.0 1 1 0 1 1 1 0 IncA protein AAA_23 PF13476.1 KHN70433.1 - 5.3 7.3 13.2 9.7 6.4 9.1 1.5 1 1 0 1 1 1 0 AAA domain DivIC PF04977.10 KHN70433.1 - 9.5 5.7 11.8 5.2 6.6 1.2 2.6 1 1 2 3 3 3 0 Septum formation initiator Aldo_ket_red PF00248.16 KHN70434.1 - 2.4e-49 167.6 0.0 2.9e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF371 PF04027.8 KHN70434.1 - 0.17 11.5 0.6 4.6 6.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF371) GLTT PF01744.15 KHN70434.1 - 0.32 10.4 3.4 0.27 10.7 0.5 2.1 2 0 0 2 2 2 0 GLTT repeat (6 copies) zf-RING_4 PF14570.1 KHN70435.1 - 0.0057 16.2 0.5 0.0082 15.7 0.4 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain WD40 PF00400.27 KHN70436.1 - 4.1e-08 32.7 17.7 0.0003 20.5 0.3 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat LisH PF08513.6 KHN70436.1 - 1.3e-07 31.0 0.4 2.7e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 LisH DUF4428 PF14471.1 KHN70436.1 - 0.026 14.2 0.9 0.074 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) UQ_con PF00179.21 KHN70438.1 - 4.1e-34 117.0 0.0 4.9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3760 PF12586.3 KHN70438.1 - 0.024 14.4 0.0 5.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) RWD PF05773.17 KHN70438.1 - 0.03 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 RWD domain EB1 PF03271.12 KHN70440.1 - 5.7e-09 35.8 6.0 2.5e-08 33.8 2.9 2.8 2 0 0 2 2 2 1 EB1-like C-terminal motif DUF1002 PF06207.6 KHN70440.1 - 0.0018 17.6 10.6 0.011 15.0 7.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1002) CH PF00307.26 KHN70440.1 - 0.066 13.2 0.6 0.16 11.9 0.0 2.0 2 1 0 2 2 2 0 Calponin homology (CH) domain XhlA PF10779.4 KHN70440.1 - 9.7 6.1 14.3 10 6.0 5.1 3.0 3 0 0 3 3 3 0 Haemolysin XhlA NOT2_3_5 PF04153.13 KHN70441.1 - 3.7e-13 49.4 0.9 5.6e-13 48.9 0.6 1.4 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF4477 PF14780.1 KHN70442.1 - 0.00035 19.9 2.0 0.00093 18.6 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4477) CemA PF03040.9 KHN70442.1 - 0.82 9.2 7.3 1.5 8.3 0.7 2.4 2 0 0 2 2 2 0 CemA family Spore_II_R PF09551.5 KHN70442.1 - 4.4 7.3 7.3 3.1 7.8 0.4 3.3 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) Helicase_C_3 PF13625.1 KHN70443.1 - 8.4e-22 77.3 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KHN70443.1 - 2.5e-16 60.0 0.0 4.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KHN70443.1 - 3.5e-10 39.1 0.1 5.2e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KHN70443.1 - 6.1e-10 38.8 0.0 2.4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KHN70443.1 - 5.7e-09 35.7 0.0 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1373 PF07117.6 KHN70444.1 - 0.038 13.7 3.0 0.066 12.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Nol1_Nop2_Fmu PF01189.12 KHN70445.1 - 1.2e-69 234.7 0.0 1.4e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 KHN70445.1 - 2.3e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN70445.1 - 7.9e-07 28.7 0.3 1.2e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KHN70445.1 - 9.6e-07 28.9 0.1 1.5e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KHN70445.1 - 1.1e-05 24.8 0.2 1.6e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KHN70445.1 - 0.00011 21.8 0.1 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein GCD14 PF08704.5 KHN70445.1 - 0.00081 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit POR PF01558.13 KHN70445.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Methyltransf_18 PF12847.2 KHN70445.1 - 0.023 15.2 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Myb_DNA-binding PF00249.26 KHN70446.1 - 1.7e-11 43.9 1.4 0.0019 18.1 0.5 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KHN70446.1 - 3e-07 30.4 2.9 0.0013 18.7 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain zf-rbx1 PF12678.2 KHN70447.1 - 2.1e-29 101.4 13.0 2.5e-29 101.2 9.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KHN70447.1 - 2e-16 59.6 9.7 2.3e-16 59.3 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KHN70447.1 - 5.5e-08 32.5 14.1 1.9e-06 27.5 9.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.1 KHN70447.1 - 0.00059 19.8 4.4 0.00072 19.5 3.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-C3HC4 PF00097.20 KHN70447.1 - 0.001 18.6 12.7 0.0081 15.7 8.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN70447.1 - 0.0014 18.2 11.6 0.55 9.9 8.3 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KHN70447.1 - 0.028 14.4 12.6 0.82 9.7 8.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KHN70447.1 - 0.03 14.2 8.6 0.05 13.5 6.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain DUF3797 PF12677.2 KHN70447.1 - 0.044 13.4 6.1 0.51 9.9 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.1 KHN70447.1 - 0.15 11.8 12.4 3.7 7.3 8.8 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 KHN70447.1 - 0.36 10.3 4.5 0.73 9.3 3.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.10 KHN70447.1 - 0.46 9.9 5.2 2.6 7.5 0.0 2.6 3 0 0 3 3 3 0 RecR protein zf-HC5HC2H PF13771.1 KHN70447.1 - 2.5 8.3 12.6 29 4.8 8.8 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain Baculo_RING PF05883.6 KHN70447.1 - 4.3 7.1 7.3 8.5 6.2 5.0 1.6 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 KHN70447.1 - 5.8 6.9 14.6 67 3.5 10.1 2.2 1 1 0 1 1 1 0 RING-like domain GDE_N_bis PF14742.1 KHN70448.1 - 0.028 13.7 0.6 0.037 13.4 0.4 1.2 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes FTCD_C PF04961.7 KHN70448.1 - 0.086 12.2 4.2 0.1 11.9 2.4 1.5 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase OmpH PF03938.9 KHN70448.1 - 0.088 12.7 4.5 0.14 12.1 3.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KxDL PF10241.4 KHN70448.1 - 0.14 12.0 4.4 0.27 11.1 3.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein S_layer_C PF05124.7 KHN70448.1 - 0.46 10.0 3.5 0.6 9.6 2.4 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region V_ATPase_I PF01496.14 KHN70448.1 - 0.46 8.2 6.9 0.3 8.9 3.8 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Cyt-b5 PF00173.23 KHN70450.1 - 5.7e-22 77.3 0.0 6.5e-22 77.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RtcB PF01139.12 KHN70451.1 - 1.8e-126 422.5 0.0 1.9e-126 422.4 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cu-oxidase_4 PF02578.10 KHN70451.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Peptidase_S8 PF00082.17 KHN70452.1 - 1.3e-45 155.7 4.0 4.4e-44 150.7 2.7 2.1 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KHN70452.1 - 2.5e-06 27.9 0.1 7.2e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 Myb_DNA-binding PF00249.26 KHN70453.1 - 4.3e-05 23.4 0.0 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KHN70453.1 - 0.016 15.2 0.1 0.038 14.1 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cyclin_N PF00134.18 KHN70454.1 - 0.0054 16.2 0.2 0.0087 15.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SMC_N PF02463.14 KHN70455.1 - 2.6e-60 203.3 0.0 1.7e-59 200.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KHN70455.1 - 1.7e-16 60.2 0.0 7.7e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KHN70455.1 - 1.5e-12 48.1 0.5 5.8e-05 23.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KHN70455.1 - 5.6e-12 46.4 20.0 1.3e-11 45.2 0.0 3.8 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 KHN70455.1 - 0.0025 17.3 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KHN70455.1 - 0.0058 15.7 0.0 0.0058 15.7 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain Corona_S2 PF01601.11 KHN70455.1 - 0.23 9.5 2.8 1.9 6.4 0.4 2.4 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein Peptidase_S28 PF05577.7 KHN70455.1 - 0.26 9.8 1.0 0.44 9.0 0.7 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 ABC_tran PF00005.22 KHN70455.1 - 0.28 11.4 9.1 11 6.3 0.0 4.5 4 1 0 4 4 4 0 ABC transporter MS_channel PF00924.13 KHN70456.1 - 5.4e-15 55.2 1.2 9.9e-15 54.4 0.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Amino_oxidase PF01593.19 KHN70456.1 - 0.19 10.7 0.2 0.37 9.8 0.1 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Rad17 PF03215.10 KHN70457.1 - 1.8e-08 33.5 0.0 7.9e-07 28.1 0.0 2.7 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KHN70457.1 - 6.4e-07 29.6 0.0 1.8e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KHN70457.1 - 7.7e-06 26.7 0.1 3.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KHN70457.1 - 0.00011 22.5 0.1 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KHN70457.1 - 0.00027 21.0 0.2 0.004 17.2 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KHN70457.1 - 0.0014 18.6 0.0 0.04 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KHN70457.1 - 0.0022 17.1 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RuvB_N PF05496.7 KHN70457.1 - 0.0024 16.9 0.0 0.0069 15.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KHN70457.1 - 0.0027 17.1 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DNA_pol3_delta PF06144.8 KHN70457.1 - 0.0039 16.7 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 KHN70457.1 - 0.0046 15.7 0.0 0.011 14.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus T2SE PF00437.15 KHN70457.1 - 0.0058 15.5 0.0 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 KHN70457.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KHN70457.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 KHN70457.1 - 0.0091 16.1 0.0 0.059 13.5 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KHN70457.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KHN70457.1 - 0.033 14.4 0.1 0.092 13.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter BCMA-Tall_bind PF09257.5 KHN70457.1 - 0.041 13.8 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 BCMA, TALL-1 binding MobB PF03205.9 KHN70457.1 - 0.052 13.2 0.0 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_2 PF07724.9 KHN70457.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KHN70457.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 KHN70457.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KHN70457.1 - 0.079 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KHN70457.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 KHN70457.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KHN70457.1 - 0.26 11.2 1.9 0.24 11.3 0.2 1.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.1 KHN70459.1 - 6.4e-05 22.2 12.1 6.4e-05 22.2 8.4 3.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 KHN70459.1 - 0.00071 19.2 36.0 0.14 11.7 8.4 3.0 1 1 2 3 3 3 3 Coiled-coil region of CCDC155 DUF972 PF06156.8 KHN70459.1 - 0.0014 18.9 34.2 0.19 12.0 6.5 4.2 1 1 4 5 5 5 2 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 KHN70459.1 - 0.0051 16.8 15.6 0.0051 16.8 10.8 2.9 1 1 2 3 3 3 1 Seryl-tRNA synthetase N-terminal domain HOOK PF05622.7 KHN70459.1 - 0.029 12.1 31.5 0.039 11.7 21.8 1.0 1 0 0 1 1 1 0 HOOK protein Reo_sigmaC PF04582.7 KHN70459.1 - 0.046 12.8 7.6 0.17 11.0 4.6 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Spectrin PF00435.16 KHN70459.1 - 0.12 12.7 23.2 1.2 9.4 1.0 3.3 1 1 2 3 3 3 0 Spectrin repeat IncA PF04156.9 KHN70459.1 - 0.12 11.9 32.3 0.11 12.1 8.5 2.6 1 1 2 3 3 3 0 IncA protein HAP1_N PF04849.8 KHN70459.1 - 0.14 11.1 35.8 0.73 8.7 12.0 2.5 1 1 1 2 2 2 0 HAP1 N-terminal conserved region bZIP_1 PF00170.16 KHN70459.1 - 0.27 11.2 44.7 0.16 11.9 1.7 6.2 2 1 4 6 6 6 0 bZIP transcription factor ADIP PF11559.3 KHN70459.1 - 0.32 10.9 37.5 0.72 9.7 11.1 3.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 KHN70459.1 - 0.33 9.9 37.7 0.61 9.0 11.5 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 TMCO5 PF14992.1 KHN70459.1 - 0.65 9.0 36.5 0.41 9.7 13.4 2.3 1 1 1 2 2 2 0 TMCO5 family DUF2422 PF10337.4 KHN70459.1 - 0.8 8.4 5.9 1.2 7.8 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Nup54 PF13874.1 KHN70459.1 - 0.8 9.3 19.5 0.077 12.6 4.2 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 BLOC1_2 PF10046.4 KHN70459.1 - 1.5 8.9 27.0 5.6 7.1 8.8 3.3 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Taxilin PF09728.4 KHN70459.1 - 1.7 7.6 41.3 3.1 6.8 0.8 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein NPV_P10 PF05531.7 KHN70459.1 - 1.9 8.7 6.5 0.99 9.7 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 KHN70459.1 - 2 8.3 33.4 1.2 9.0 15.4 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 KHN70459.1 - 2 8.1 42.7 3.2 7.5 3.9 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 KHN70459.1 - 2.4 8.2 24.4 5 7.2 3.0 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tup_N PF08581.5 KHN70459.1 - 2.4 8.4 22.7 0.077 13.1 2.2 3.7 1 1 3 4 4 4 0 Tup N-terminal CENP-Q PF13094.1 KHN70459.1 - 2.4 8.1 30.1 1.2 9.1 12.8 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 KHN70459.1 - 2.8 6.2 30.1 0.73 8.1 10.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) ATG16 PF08614.6 KHN70459.1 - 3 7.6 34.3 27 4.5 10.8 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.1 KHN70459.1 - 3.5 6.6 40.3 4.4 6.3 17.6 3.2 1 1 2 3 3 3 0 Leucine zipper Med28 PF11594.3 KHN70459.1 - 4.2 7.6 17.3 0.23 11.7 6.0 2.8 1 1 1 2 2 2 0 Mediator complex subunit 28 Adeno_PIX PF03955.9 KHN70459.1 - 4.2 7.9 7.9 5.6 7.5 0.4 2.4 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Laminin_II PF06009.7 KHN70459.1 - 4.4 7.0 24.5 14 5.3 6.9 2.7 1 1 1 2 2 2 0 Laminin Domain II Nsp1_C PF05064.8 KHN70459.1 - 4.8 6.8 18.7 0.23 11.0 1.5 2.8 2 1 1 3 3 2 0 Nsp1-like C-terminal region Cep57_CLD_2 PF14197.1 KHN70459.1 - 5.4 7.0 37.0 4.2 7.3 4.7 4.5 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 Tropomyosin_1 PF12718.2 KHN70459.1 - 6.5 6.5 41.8 0.24 11.2 4.0 2.9 1 1 2 3 3 3 0 Tropomyosin like Med30 PF11315.3 KHN70459.1 - 8.3 6.5 21.7 9.3 6.3 6.8 3.2 1 1 2 3 3 3 0 Mediator complex subunit 30 DivIC PF04977.10 KHN70459.1 - 8.8 5.9 40.0 0.85 9.1 2.9 5.9 2 1 4 6 6 6 0 Septum formation initiator TSC22 PF01166.13 KHN70459.1 - 8.9 6.3 30.4 5.3 7.0 1.8 5.9 3 1 3 6 6 5 0 TSC-22/dip/bun family CALCOCO1 PF07888.6 KHN70459.1 - 9.9 4.3 28.1 39 2.3 19.5 1.8 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF904 PF06005.7 KHN70459.1 - 9.9 6.5 46.3 0.54 10.5 10.2 4.8 1 1 3 4 4 3 0 Protein of unknown function (DUF904) Dynamin_N PF00350.18 KHN70460.1 - 9.8e-38 129.6 0.1 1.8e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KHN70460.1 - 1.9e-33 115.5 2.1 3e-23 82.0 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KHN70460.1 - 2.7e-08 33.6 1.0 9.5e-08 31.8 0.7 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KHN70460.1 - 0.00014 21.8 0.2 0.00049 20.0 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KHN70460.1 - 0.071 12.6 0.1 1.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Guanylate_kin PF00625.16 KHN70461.1 - 2.5e-37 128.1 0.0 2.8e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KHN70461.1 - 1.7e-06 28.3 1.8 8.4e-06 26.1 1.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KHN70461.1 - 0.00026 20.4 0.6 0.00046 19.6 0.4 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KHN70461.1 - 0.00083 20.1 2.6 0.0031 18.3 1.8 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KHN70461.1 - 0.0011 18.8 1.7 0.38 10.6 0.3 3.1 2 2 1 3 3 3 1 AAA domain AAA_22 PF13401.1 KHN70461.1 - 0.0039 17.3 0.1 0.013 15.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KHN70461.1 - 0.0063 15.9 0.5 0.051 12.9 0.0 2.2 2 1 1 3 3 3 1 Thymidylate kinase ABC_tran PF00005.22 KHN70461.1 - 0.0079 16.5 0.1 0.013 15.7 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 KHN70461.1 - 0.015 15.3 0.0 0.017 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 KHN70461.1 - 0.016 14.9 0.7 0.071 12.8 0.1 2.0 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 KHN70461.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 KHN70461.1 - 0.036 13.2 0.0 0.062 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 KHN70461.1 - 0.045 14.0 1.7 0.098 12.9 1.2 1.7 1 1 0 1 1 1 0 AAA domain CoaE PF01121.15 KHN70461.1 - 0.049 13.0 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_19 PF13245.1 KHN70461.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 KHN70461.1 - 0.086 12.7 0.1 0.37 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KHN70461.1 - 0.097 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 KHN70461.1 - 0.15 11.6 0.4 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.24 KHN70462.1 - 1.2e-99 329.6 0.0 2e-48 163.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KHN70462.1 - 8.8e-15 54.3 0.0 1.2e-06 27.7 0.0 3.0 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KHN70462.1 - 6.9e-14 52.1 0.8 9.4e-05 22.5 0.1 4.7 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.9 KHN70462.1 - 5.2e-13 49.2 0.0 5.9e-06 26.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KHN70462.1 - 5e-12 45.7 0.2 2.4e-05 24.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KHN70462.1 - 9.9e-12 45.2 0.8 0.00053 20.0 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 KHN70462.1 - 1.2e-11 45.4 0.1 6.9e-05 23.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KHN70462.1 - 5.9e-11 42.3 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KHN70462.1 - 8e-11 41.9 0.0 4.3e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KHN70462.1 - 2e-09 37.1 3.4 0.053 12.9 0.0 4.3 2 2 2 4 4 4 3 AAA domain TIP49 PF06068.8 KHN70462.1 - 3.8e-09 35.7 0.1 0.0014 17.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KHN70462.1 - 5.1e-09 35.8 1.5 0.0035 16.7 0.0 4.0 4 1 0 4 4 4 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 KHN70462.1 - 8.3e-08 31.5 0.0 0.01 14.9 0.0 3.0 2 1 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 KHN70462.1 - 1.1e-07 31.9 0.0 0.01 15.9 0.0 3.1 2 1 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 KHN70462.1 - 2.4e-07 31.1 0.0 0.0057 16.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 KHN70462.1 - 4.1e-07 29.3 0.4 0.025 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ResIII PF04851.10 KHN70462.1 - 4.6e-07 29.8 0.0 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KHN70462.1 - 7e-07 29.3 0.0 0.087 12.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KHN70462.1 - 1.6e-06 27.7 2.8 0.0071 16.0 0.3 2.8 2 0 0 2 2 2 2 Part of AAA domain Arch_ATPase PF01637.13 KHN70462.1 - 1.9e-06 27.7 0.7 1.7 8.2 0.0 3.8 2 2 2 4 4 4 2 Archaeal ATPase CDC48_N PF02359.13 KHN70462.1 - 2.6e-06 27.2 0.1 7.9e-06 25.7 0.0 1.8 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Parvo_NS1 PF01057.12 KHN70462.1 - 3.9e-06 25.9 0.3 0.017 13.9 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 KHN70462.1 - 4.6e-06 26.7 0.0 0.028 14.4 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KHN70462.1 - 5.5e-06 26.7 0.1 0.13 12.5 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.13 KHN70462.1 - 1.4e-05 24.8 0.0 0.018 14.6 0.0 3.0 3 0 0 3 3 3 1 Bacterial dnaA protein DUF815 PF05673.8 KHN70462.1 - 2e-05 23.6 0.0 0.032 13.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_24 PF13479.1 KHN70462.1 - 2.4e-05 24.0 0.1 0.31 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KHN70462.1 - 2.7e-05 23.6 0.0 0.19 11.2 0.0 3.7 2 2 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KHN70462.1 - 3e-05 23.7 0.3 0.35 10.5 0.0 3.7 4 0 0 4 4 4 1 NACHT domain AAA_11 PF13086.1 KHN70462.1 - 0.00015 21.4 0.2 0.029 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain PhoH PF02562.11 KHN70462.1 - 0.00025 20.3 0.5 0.58 9.3 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 KHN70462.1 - 0.00031 20.3 0.0 0.54 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KHN70462.1 - 0.00053 18.9 0.1 0.68 8.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 KHN70462.1 - 0.00057 19.4 0.0 0.075 12.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 KHN70462.1 - 0.0008 18.5 5.0 0.82 8.7 0.0 4.0 4 1 1 5 5 3 2 KaiC NTPase_1 PF03266.10 KHN70462.1 - 0.00083 19.1 0.7 1.3 8.7 0.0 4.0 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 KHN70462.1 - 0.0012 17.9 0.0 0.21 10.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Vps4_C PF09336.5 KHN70462.1 - 0.0022 17.8 0.1 0.018 14.9 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain UPF0079 PF02367.12 KHN70462.1 - 0.01 15.4 0.1 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 KHN70462.1 - 0.016 15.1 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.20 KHN70462.1 - 0.016 14.7 0.0 7.5 5.9 0.0 2.8 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin2 PF13189.1 KHN70462.1 - 0.027 14.3 0.6 1.5 8.7 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase-like family T2SE PF00437.15 KHN70462.1 - 0.037 12.9 0.0 9.1 5.0 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 KHN70462.1 - 0.052 12.9 0.3 13 5.0 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain AAA_30 PF13604.1 KHN70462.1 - 0.052 13.1 0.1 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KHN70462.1 - 0.075 12.0 0.0 2.9 6.7 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 KHN70462.1 - 0.11 11.9 0.2 17 4.8 0.1 3.6 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 KHN70462.1 - 0.28 11.4 6.8 6.1 7.1 0.6 3.5 3 1 0 3 3 3 0 AAA domain MS_channel PF00924.13 KHN70463.1 - 2.8e-12 46.4 2.3 2.8e-12 46.4 0.2 2.1 2 0 0 2 2 2 1 Mechanosensitive ion channel C2 PF00168.25 KHN70464.1 - 2.2e-16 59.4 0.1 1.4e-10 40.8 0.0 4.2 4 1 0 4 4 4 2 C2 domain CEP76-C2 PF15627.1 KHN70464.1 - 0.14 11.6 0.7 0.91 9.0 0.0 2.5 2 1 1 3 3 3 0 CEP76 C2 domain EF-hand_6 PF13405.1 KHN70465.1 - 0.0063 16.2 0.3 0.35 10.8 0.0 3.0 4 0 0 4 4 4 1 EF-hand domain Prefoldin_3 PF13758.1 KHN70465.1 - 0.039 13.7 0.8 0.15 11.8 0.1 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF3860 PF12976.2 KHN70465.1 - 0.068 12.9 0.9 0.32 10.8 0.1 2.0 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) mRNA_stabil PF13929.1 KHN70465.1 - 0.07 12.0 2.7 0.062 12.2 1.1 1.4 1 1 0 1 1 1 0 mRNA stabilisation EF-hand_7 PF13499.1 KHN70465.1 - 0.082 13.0 0.1 1.2 9.2 0.0 2.3 1 1 2 3 3 3 0 EF-hand domain pair PRESAN PF09687.5 KHN70465.1 - 0.085 12.9 4.1 0.4 10.7 0.5 2.6 1 1 1 3 3 3 0 Plasmodium RESA N-terminal HTH_44 PF14641.1 KHN70465.1 - 0.1 12.5 2.5 0.13 12.2 0.4 1.9 1 1 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 CS PF04969.11 KHN70467.1 - 3.3e-10 40.3 0.1 4.9e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 CS domain WD40 PF00400.27 KHN70468.1 - 2.7e-46 153.8 6.6 2.7e-10 39.7 0.2 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KHN70468.1 - 2.7e-35 122.0 0.0 4.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KHN70468.1 - 4.5e-09 35.3 0.1 4.5e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus TPR_11 PF13414.1 KHN70468.1 - 0.13 11.8 0.1 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Nup160 PF11715.3 KHN70468.1 - 0.14 10.2 0.1 8.9 4.3 0.0 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.27 KHN70469.1 - 1.2e-40 135.8 10.8 9.5e-09 34.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat CPSF_A PF03178.10 KHN70469.1 - 0.019 14.0 0.0 0.047 12.7 0.0 1.7 1 0 0 1 1 1 0 CPSF A subunit region PQQ_2 PF13360.1 KHN70469.1 - 0.058 12.8 0.0 0.45 9.9 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Autophagy_Cterm PF10381.4 KHN70469.1 - 0.092 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Nup160 PF11715.3 KHN70469.1 - 0.11 10.5 0.3 1.1 7.2 0.2 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 IF4E PF01652.13 KHN70469.1 - 0.13 11.7 1.0 0.23 11.0 0.3 1.6 2 0 0 2 2 2 0 Eukaryotic initiation factor 4E Frataxin_Cyay PF01491.11 KHN70470.1 - 1.2e-23 82.9 0.1 1.5e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 Frataxin-like domain DUF1896 PF08989.5 KHN70470.1 - 0.047 13.5 0.0 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) Pkinase PF00069.20 KHN70471.1 - 1.2e-50 172.1 0.2 3.8e-50 170.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70471.1 - 1.6e-22 79.8 0.1 4.9e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase C1_1 PF00130.17 KHN70471.1 - 5.6e-10 38.7 2.2 5.6e-10 38.7 1.5 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 KHN70471.1 - 6e-09 35.2 0.0 9.7e-09 34.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HR1 PF02185.11 KHN70471.1 - 3.3e-06 26.7 2.4 3.3e-06 26.7 1.7 4.0 3 2 1 4 4 4 1 Hr1 repeat APH PF01636.18 KHN70471.1 - 0.00097 18.9 0.2 0.0027 17.4 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family PHD_2 PF13831.1 KHN70471.1 - 0.0016 17.7 2.5 0.004 16.4 1.7 1.7 1 0 0 1 1 1 1 PHD-finger Kdo PF06293.9 KHN70471.1 - 0.0058 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 KHN70471.1 - 0.1 12.3 4.6 0.26 11.0 3.2 1.7 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 KHN70471.1 - 0.17 11.9 5.8 0.42 10.6 4.1 1.7 1 0 0 1 1 1 0 C1-like domain zf-RING-like PF08746.6 KHN70471.1 - 0.18 11.8 3.3 0.73 9.8 2.3 2.1 1 0 0 1 1 1 0 RING-like domain DUF2407_C PF13373.1 KHN70471.1 - 0.27 11.1 2.7 0.4 10.6 0.8 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain AAA_23 PF13476.1 KHN70471.1 - 2.3 8.5 28.1 0.14 12.4 3.2 3.2 3 0 0 3 3 3 0 AAA domain Abhydrolase_6 PF12697.2 KHN70472.1 - 5.1e-13 49.4 0.0 6.4e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KHN70472.1 - 1.8e-09 37.5 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KHN70472.1 - 4.5e-06 25.5 0.0 6.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KHN70472.1 - 0.00014 21.4 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KHN70472.1 - 0.0054 16.5 0.0 0.017 14.9 0.0 1.9 1 1 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KHN70472.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF900 PF05990.7 KHN70472.1 - 0.047 13.0 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.16 KHN70472.1 - 0.073 12.2 0.0 8.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family TFIID-31kDa PF02291.10 KHN70473.1 - 4.9e-28 97.5 0.0 5.3e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 KHN70473.1 - 9.3e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 KHN70473.1 - 1.6e-06 27.7 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 KHN70473.1 - 9.8e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KHN70473.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Vps5 PF09325.5 KHN70474.1 - 0.048 12.9 6.4 0.032 13.4 1.5 2.1 2 0 0 2 2 2 0 Vps5 C terminal like PEMT PF04191.8 KHN70475.1 - 1.5e-06 28.2 1.4 1.5e-06 28.2 1.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KHN70475.1 - 4.1e-06 26.8 3.6 5.1e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 KHN70475.1 - 7.4e-06 25.4 1.7 1.2e-05 24.7 1.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 KHN70475.1 - 0.041 13.2 2.5 0.099 12.0 1.7 1.7 1 1 0 1 1 1 0 NnrU protein Gar1 PF04410.9 KHN70476.1 - 8.6e-17 61.0 1.1 8.6e-17 61.0 0.8 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DUF1366 PF07104.6 KHN70476.1 - 0.00033 20.2 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1366) Menin PF05053.8 KHN70476.1 - 7.8 4.5 12.4 9 4.3 8.6 1.1 1 0 0 1 1 1 0 Menin Septin PF00735.13 KHN70477.1 - 5.6e-61 206.0 0.0 1e-60 205.1 0.0 1.4 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.18 KHN70477.1 - 0.0091 15.8 1.4 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 KHN70477.1 - 0.029 14.8 0.1 0.097 13.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein GP41 PF00517.12 KHN70478.1 - 0.1 12.1 0.1 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Retroviral envelope protein RNA_pol_Rpb1_1 PF04997.7 KHN70478.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Chitin_synth_2 PF03142.10 KHN70479.1 - 7.2e-201 668.1 11.6 7.6e-105 351.2 0.8 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 KHN70479.1 - 6.1e-20 72.0 0.0 5.3e-16 59.1 0.0 2.7 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KHN70479.1 - 3.7e-19 69.2 0.4 3.7e-19 69.2 0.3 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KHN70479.1 - 9.1e-09 35.2 0.1 0.0013 18.4 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KHN70479.1 - 1.7e-07 30.6 0.0 2.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF4461 PF14688.1 KHN70480.1 - 0.026 13.8 0.1 3.4 6.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4461) Pkinase PF00069.20 KHN70481.1 - 5.7e-34 117.4 0.1 6.8e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70481.1 - 5.8e-16 58.3 0.3 2.2e-15 56.4 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KHN70481.1 - 0.0041 16.2 0.3 0.0072 15.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KHN70481.1 - 0.0071 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KHN70481.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 KHN70481.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like PIP49_C PF12260.3 KHN70481.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pox_ser-thr_kin PF05445.6 KHN70481.1 - 0.043 12.6 0.5 0.13 10.9 0.1 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KHN70481.1 - 0.099 11.9 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family SGS PF05002.10 KHN70482.1 - 5.8e-19 67.6 2.6 9.1e-19 67.0 1.8 1.4 1 1 0 1 1 1 1 SGS domain CPSF_A PF03178.10 KHN70483.1 - 2.2e-11 43.4 8.8 5.3e-11 42.1 1.6 3.3 3 1 0 3 3 3 1 CPSF A subunit region XAP5 PF04921.9 KHN70483.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Metallothio_6 PF05522.6 KHN70483.1 - 1.8 8.8 5.5 0.29 11.4 0.7 2.0 2 0 0 2 2 2 0 Metallothionein AAA PF00004.24 KHN70484.1 - 3.6e-58 195.4 0.3 1.7e-45 154.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KHN70484.1 - 4.4e-12 46.3 0.6 0.00033 20.6 0.1 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KHN70484.1 - 1.7e-11 44.4 0.0 0.0016 18.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 KHN70484.1 - 4.2e-11 42.8 0.0 5.4e-06 26.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KHN70484.1 - 1.1e-08 35.9 0.2 0.0097 16.7 0.0 2.9 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KHN70484.1 - 4.5e-08 32.9 0.1 0.00094 18.9 0.0 3.8 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KHN70484.1 - 5.4e-07 29.9 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RuvB_N PF05496.7 KHN70484.1 - 8.2e-07 28.3 0.0 0.0056 15.7 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 KHN70484.1 - 6.1e-06 25.9 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.13 KHN70484.1 - 9.8e-06 25.3 0.2 0.65 9.5 0.0 3.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_33 PF13671.1 KHN70484.1 - 1e-05 25.4 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KHN70484.1 - 1.1e-05 25.1 0.9 0.37 10.4 0.0 3.7 2 1 0 2 2 2 2 NACHT domain Sigma54_activ_2 PF14532.1 KHN70484.1 - 1.2e-05 25.3 0.0 0.092 12.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.9 KHN70484.1 - 1.3e-05 25.1 0.0 0.002 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 KHN70484.1 - 1.7e-05 24.4 0.3 0.12 12.1 0.0 3.2 2 1 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 KHN70484.1 - 3e-05 23.1 0.0 0.012 14.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 KHN70484.1 - 4.7e-05 22.8 0.0 1.9 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KHN70484.1 - 8.3e-05 22.3 2.0 0.17 11.5 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 KHN70484.1 - 0.00011 22.3 0.0 0.053 13.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 KHN70484.1 - 0.00012 21.4 0.1 0.4 10.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KHN70484.1 - 0.00013 22.2 0.3 0.12 12.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 KHN70484.1 - 0.00021 20.4 1.2 0.33 10.0 0.0 3.5 4 1 0 4 4 4 1 KaiC DUF815 PF05673.8 KHN70484.1 - 0.00023 20.2 0.0 0.28 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF258 PF03193.11 KHN70484.1 - 0.00038 19.6 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_3 PF07726.6 KHN70484.1 - 0.00083 18.9 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KHN70484.1 - 0.00099 18.3 0.1 0.079 12.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 KHN70484.1 - 0.0015 18.5 0.0 0.082 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KHN70484.1 - 0.0016 17.9 0.0 4 6.8 0.0 3.3 3 1 0 3 3 3 0 Sigma-54 interaction domain CPT PF07931.7 KHN70484.1 - 0.0016 18.0 0.0 0.73 9.4 0.0 2.9 3 0 0 3 3 3 1 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 KHN70484.1 - 0.002 17.0 0.0 1.2 7.9 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain KAP_NTPase PF07693.9 KHN70484.1 - 0.0027 16.7 0.1 0.32 9.9 0.0 2.6 2 1 1 3 3 3 1 KAP family P-loop domain AAA_24 PF13479.1 KHN70484.1 - 0.0041 16.7 0.0 0.42 10.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 KHN70484.1 - 0.0047 15.6 0.0 0.43 9.2 0.0 2.9 3 0 0 3 3 3 1 TIP49 C-terminus ATP-synt_ab PF00006.20 KHN70484.1 - 0.0069 15.9 0.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 KHN70484.1 - 0.01 15.4 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KHN70484.1 - 0.014 14.8 0.1 1.8 7.9 0.0 3.0 3 1 0 3 3 3 0 AAA-like domain Rad17 PF03215.10 KHN70484.1 - 0.017 13.8 0.1 0.27 9.8 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MCM PF00493.18 KHN70484.1 - 0.019 13.7 0.1 2.8 6.6 0.0 2.2 1 1 1 2 2 2 0 MCM2/3/5 family SRPRB PF09439.5 KHN70484.1 - 0.033 13.3 0.0 6.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 KHN70484.1 - 0.034 13.8 1.8 4.9 6.8 0.0 3.5 3 1 1 4 4 4 0 NTPase AAA_29 PF13555.1 KHN70484.1 - 0.051 13.0 0.0 16 5.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.17 KHN70484.1 - 0.06 13.2 0.0 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.4 KHN70484.1 - 0.095 12.1 0.0 10 5.5 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KHN70484.1 - 0.12 11.8 0.6 6.3 6.2 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 KHN70484.1 - 0.13 11.8 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KHN70484.1 - 0.19 11.7 0.4 31 4.5 0.1 3.2 2 2 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 KHN70485.1 - 0.1 12.2 0.1 13 5.4 0.0 2.3 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RHH_3 PF12651.2 KHN70485.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain tRNA-synt_1b PF00579.20 KHN70486.1 - 5.5e-56 189.8 0.0 6.8e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2024 PF09630.5 KHN70486.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Feld-I_B PF09252.5 KHN70486.1 - 0.063 13.1 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 Allergen Fel d I-B chain zf-RING_2 PF13639.1 KHN70487.1 - 4.4e-06 26.4 8.6 1.2e-05 25.0 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 KHN70487.1 - 2.6e-05 23.9 7.1 2.6e-05 23.9 4.9 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KHN70487.1 - 2.7e-05 24.1 10.0 2.7e-05 24.1 6.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KHN70487.1 - 0.0042 16.7 5.6 0.013 15.1 3.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KHN70487.1 - 0.019 14.9 6.3 0.051 13.6 4.3 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 KHN70487.1 - 0.028 14.4 4.3 0.1 12.6 3.0 2.0 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 KHN70487.1 - 0.15 12.0 12.0 0.032 14.2 5.0 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 KHN70487.1 - 0.62 9.6 6.6 1.5 8.4 4.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 KHN70487.1 - 0.67 10.0 11.6 2.5 8.2 7.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KHN70487.1 - 1.6 8.4 10.2 9.7 5.9 6.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1422 PF07226.6 KHN70488.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) PCI PF01399.22 KHN70489.1 - 5.2e-13 49.2 2.7 1.5e-12 47.7 0.1 3.0 4 0 0 4 4 4 1 PCI domain RPN7 PF10602.4 KHN70489.1 - 9.9e-05 21.7 0.3 0.0006 19.2 0.1 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 DUF383 PF04063.9 KHN70489.1 - 0.011 15.3 0.1 0.028 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF383) FlgN PF05130.7 KHN70489.1 - 0.05 13.8 0.1 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 FlgN protein RIO1 PF01163.17 KHN70491.1 - 3.9e-58 195.9 1.2 3.9e-58 195.9 0.9 2.4 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 KHN70491.1 - 0.014 15.1 0.0 2.2 7.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.9 KHN70491.1 - 0.019 13.0 2.5 0.027 12.5 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Kdo PF06293.9 KHN70491.1 - 0.16 10.9 1.5 0.5 9.3 0.0 2.4 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpb4 PF03874.11 KHN70492.1 - 3.4e-16 59.2 3.6 5.7e-16 58.5 2.5 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 ANTAR PF03861.9 KHN70492.1 - 0.012 15.1 0.2 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 ANTAR domain POT1 PF02765.12 KHN70493.1 - 7.5e-08 32.4 0.5 2.8e-07 30.5 0.1 2.0 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 KHN70493.1 - 0.0004 20.1 2.1 0.057 13.2 0.4 3.6 4 0 0 4 4 4 1 OB-fold nucleic acid binding domain PCNA_N PF00705.13 KHN70495.1 - 2.8e-21 75.3 0.7 4.3e-21 74.7 0.5 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KHN70495.1 - 3.5e-10 39.8 0.1 9.1e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KHN70495.1 - 0.004 16.2 0.1 0.0066 15.6 0.1 1.4 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KHN70495.1 - 0.026 13.2 0.0 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 DKCLD PF08068.7 KHN70496.1 - 1.9e-23 82.1 0.0 4.5e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 KHN70496.1 - 1.3e-21 77.2 0.1 1.8e-15 57.4 0.0 3.1 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KHN70496.1 - 1.9e-16 59.5 0.3 4.6e-16 58.3 0.2 1.7 1 0 0 1 1 1 1 PUA domain WD40 PF00400.27 KHN70497.1 - 5.6e-08 32.3 5.7 0.0046 16.8 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Arf PF00025.16 KHN70498.1 - 7e-21 74.2 0.1 8.5e-21 73.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KHN70498.1 - 4.1e-06 27.2 0.0 1.2e-05 25.8 0.0 1.7 1 1 1 2 2 2 1 Miro-like protein G-alpha PF00503.15 KHN70498.1 - 9.1e-06 24.6 0.1 0.016 13.9 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KHN70498.1 - 0.00031 20.1 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KHN70498.1 - 0.00045 20.1 0.0 0.0007 19.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KHN70498.1 - 0.0029 16.7 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KHN70498.1 - 0.035 13.3 0.1 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein NTPase_1 PF03266.10 KHN70498.1 - 0.043 13.5 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 KHN70498.1 - 0.089 12.6 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KHN70498.1 - 0.12 11.7 0.1 0.61 9.5 0.0 2.0 2 1 1 3 3 3 0 FtsK/SpoIIIE family DNA_pol_B PF00136.16 KHN70499.1 - 5.1e-95 318.9 0.4 7.1e-95 318.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B INTS5_C PF14838.1 KHN70499.1 - 0.24 9.6 0.0 0.44 8.7 0.0 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus APC10 PF03256.11 KHN70500.1 - 6.7e-30 104.1 0.2 8.4e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Fe_hyd_lg_C PF02906.9 KHN70501.1 - 6.1e-33 114.3 0.5 1.1e-32 113.4 0.3 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain WBS_methylT PF12589.3 KHN70502.1 - 1.2e-11 44.8 8.6 2.2e-11 44.0 6.0 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KHN70502.1 - 3.2e-10 40.3 0.0 5.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KHN70502.1 - 4.1e-08 33.0 0.0 6.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KHN70502.1 - 7.7e-06 25.1 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KHN70502.1 - 9.6e-06 26.1 0.1 1.9e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KHN70502.1 - 1.7e-05 24.4 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KHN70502.1 - 2.7e-05 24.4 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KHN70502.1 - 4.6e-05 23.8 0.0 9.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KHN70502.1 - 5.8e-05 22.7 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6_N4_Mtase PF01555.13 KHN70502.1 - 0.00024 20.6 0.0 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 DNA methylase MetW PF07021.7 KHN70502.1 - 0.052 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KHN70502.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KHN70502.1 - 0.14 11.4 0.3 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KHN70502.1 - 0.17 11.0 0.2 0.32 10.0 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DEAD PF00270.24 KHN70503.1 - 2.3e-17 62.9 0.0 2.1e-16 59.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 KHN70503.1 - 1.1e-10 41.6 0.1 7e-09 35.7 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KHN70503.1 - 1e-09 38.0 0.0 3.4e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 KHN70503.1 - 1.5 8.3 4.3 47 3.4 0.2 3.8 5 0 0 5 5 5 0 AAA domain IP_trans PF02121.13 KHN70504.1 - 7.8e-29 100.6 0.9 1.1e-28 100.1 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein S4 PF01479.20 KHN70505.1 - 1.6e-05 24.2 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 KHN70505.1 - 0.0059 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain LSM PF01423.17 KHN70506.1 - 4.6e-13 48.4 0.0 6.3e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L21e PF01157.13 KHN70507.1 - 4e-33 113.1 5.0 5.7e-33 112.6 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF4378 PF14309.1 KHN70507.1 - 0.034 14.2 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Bunya_RdRp PF04196.7 KHN70507.1 - 0.055 11.4 0.2 0.067 11.2 0.1 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Ribosomal_S6 PF01250.12 KHN70507.1 - 0.42 10.4 3.2 1.9 8.3 0.2 2.6 1 1 2 3 3 3 0 Ribosomal protein S6 Brr6_like_C_C PF10104.4 KHN70508.1 - 1.1e-35 122.1 0.1 1.8e-35 121.4 0.1 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF912 PF06024.7 KHN70508.1 - 0.24 11.4 3.5 0.6 10.1 2.4 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SecE PF00584.15 KHN70509.1 - 9.3e-11 41.1 0.0 1.1e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF4073 PF13285.1 KHN70510.1 - 0.0072 15.7 1.3 0.012 15.0 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4073) Chordopox_G3 PF06129.7 KHN70510.1 - 0.76 9.9 3.1 7.9 6.6 0.0 2.9 3 0 0 3 3 3 0 Chordopoxvirus G3 protein Ham1p_like PF01725.11 KHN70511.1 - 8e-15 54.6 0.0 1.5e-14 53.8 0.0 1.4 2 0 0 2 2 2 1 Ham1 family 6PGD PF00393.14 KHN70512.1 - 7.2e-84 281.4 1.5 9e-84 281.1 1.1 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KHN70512.1 - 7.2e-41 139.7 0.1 1.5e-40 138.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KHN70512.1 - 1.3e-06 28.7 0.4 4.3e-05 23.8 0.0 2.8 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KHN70512.1 - 5.8e-05 23.2 0.0 0.00033 20.7 0.0 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KHN70512.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KHN70512.1 - 0.014 14.8 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KHN70512.1 - 0.018 14.7 0.0 0.055 13.1 0.0 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KHN70512.1 - 0.051 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PX PF00787.19 KHN70514.1 - 8.6e-13 48.0 0.2 1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 PX domain CPG4 PF15481.1 KHN70514.1 - 0.13 12.6 1.4 0.3 11.4 0.1 2.0 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 Clathrin PF00637.15 KHN70515.1 - 0.042 13.4 1.4 2 7.9 0.3 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS SNARE PF05739.14 KHN70516.1 - 0.092 12.4 6.6 0.08 12.6 2.7 2.2 2 0 0 2 2 2 0 SNARE domain Asp-B-Hydro_N PF05279.6 KHN70516.1 - 4.3 7.1 7.1 6.2 6.6 4.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NOG1 PF06858.9 KHN70518.1 - 1.1e-21 76.4 0.5 2.6e-21 75.2 0.1 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KHN70518.1 - 2.7e-16 59.5 0.0 1e-15 57.6 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.6 KHN70518.1 - 1.9e-10 40.2 3.6 6.3e-10 38.5 2.5 1.9 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.13 KHN70518.1 - 9.3e-10 37.9 0.1 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KHN70518.1 - 0.0072 16.8 0.1 0.028 14.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 KHN70518.1 - 0.016 14.3 0.1 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family MobB PF03205.9 KHN70518.1 - 0.022 14.4 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KHN70518.1 - 0.028 14.2 0.1 2.9 7.6 0.0 2.8 1 1 1 2 2 2 0 Dynamin family DUF258 PF03193.11 KHN70518.1 - 0.03 13.5 0.0 0.25 10.5 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KHN70518.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_tranf_2_3 PF13641.1 KHN70519.1 - 0.041 13.6 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Herpes_BMRF2 PF04633.7 KHN70520.1 - 0.022 13.7 2.0 0.031 13.2 1.4 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein UNC-93 PF05978.11 KHN70520.1 - 0.042 13.3 1.1 0.053 13.0 0.8 1.1 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 Abi PF02517.11 KHN70520.1 - 0.13 12.3 0.8 0.16 12.1 0.5 1.1 1 0 0 1 1 1 0 CAAX protease self-immunity DUF1625 PF07787.7 KHN70520.1 - 0.27 10.4 3.5 0.35 10.0 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DPM2 PF07297.7 KHN70520.1 - 3.8 7.8 6.7 1.2 9.4 1.5 1.9 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MCM PF00493.18 KHN70521.1 - 1.1e-129 432.0 1.1 1.5e-129 431.5 0.8 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KHN70521.1 - 8.1e-12 45.7 1.4 3e-11 43.8 1.0 2.1 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KHN70521.1 - 6.7e-10 38.4 0.0 8.8e-07 28.2 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KHN70521.1 - 2.1e-07 30.7 0.0 7.1e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KHN70521.1 - 1.1e-05 25.0 0.0 2.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KHN70521.1 - 0.00014 21.3 0.3 0.0013 18.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain GAT PF03127.9 KHN70522.1 - 0.024 14.5 0.0 0.027 14.4 0.0 1.1 1 0 0 1 1 1 0 GAT domain DUF383 PF04063.9 KHN70522.1 - 0.12 11.8 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Mst1_SARAH PF11629.3 KHN70522.1 - 0.58 10.0 2.9 21 5.0 0.1 2.8 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 Peptidase_C48 PF02902.14 KHN70523.1 - 1.6e-33 116.1 0.8 2.1e-33 115.7 0.6 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KHN70523.1 - 0.00061 18.4 0.1 0.1 11.0 0.0 2.2 1 1 1 2 2 2 2 Vaccinia virus I7 processing peptidase EF-hand_1 PF00036.27 KHN70524.1 - 0.0091 15.2 0.0 8.9 5.8 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KHN70524.1 - 0.014 15.5 1.5 4.4 7.5 0.0 3.1 2 2 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.1 KHN70524.1 - 0.13 11.8 0.7 1.2 8.7 0.1 2.6 2 1 0 2 2 2 0 EF-hand domain pair WD40 PF00400.27 KHN70525.1 - 0.059 13.2 1.8 1.5 8.8 0.1 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_3 PF13570.1 KHN70525.1 - 0.18 12.1 2.0 7 7.0 0.0 4.0 5 0 0 5 5 5 0 PQQ-like domain Aminotran_1_2 PF00155.16 KHN70526.1 - 1.3e-50 172.4 0.0 1.5e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KHN70526.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KHN70526.1 - 0.013 14.5 0.1 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KHN70526.1 - 0.015 13.6 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KHN70526.1 - 0.034 12.8 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.15 KHN70526.1 - 0.09 11.3 0.2 0.17 10.3 0.1 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain RRM_6 PF14259.1 KHN70527.1 - 5.2e-05 23.1 0.0 0.035 14.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RhoGAP PF00620.22 KHN70528.1 - 2.2e-24 85.8 0.1 2.2e-24 85.8 0.1 1.5 2 0 0 2 2 2 1 RhoGAP domain Spc97_Spc98 PF04130.8 KHN70529.1 - 1.7e-16 59.6 2.7 4.7e-14 51.6 1.8 2.9 1 1 0 1 1 1 1 Spc97 / Spc98 family GWT1 PF06423.7 KHN70530.1 - 1.9e-19 70.1 9.1 1.9e-19 70.1 6.3 2.7 3 1 0 3 3 3 1 GWT1 PseudoU_synth_2 PF00849.17 KHN70531.1 - 3.3e-28 98.5 0.0 6e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.13 KHN70531.1 - 2e-06 28.0 0.0 4.4e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Ribosomal_S6e PF01092.14 KHN70532.1 - 1.2e-45 154.2 1.1 2e-45 153.5 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e PTPS PF01242.14 KHN70532.1 - 0.014 15.1 0.1 0.028 14.0 0.0 1.6 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase BIR PF00653.16 KHN70533.1 - 7.7e-18 64.6 6.7 8.7e-16 58.1 1.8 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain PGI PF00342.14 KHN70534.1 - 5.6e-144 480.1 1.6 6.8e-144 479.9 1.1 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 KHN70536.1 - 7.4e-51 172.7 0.0 1.2e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KHN70536.1 - 2.3e-35 121.9 0.0 3.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 KHN70536.1 - 0.044 13.4 0.1 0.17 11.5 0.2 2.0 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C terminal LRR_6 PF13516.1 KHN70537.1 - 4.1e-13 47.9 1.4 1.3 9.3 0.0 7.5 9 0 0 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.28 KHN70537.1 - 1.3e-10 39.8 2.9 9.2 6.7 0.0 7.9 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_4 PF12799.2 KHN70537.1 - 3.5e-09 36.0 0.2 0.87 9.2 0.0 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KHN70537.1 - 0.012 15.6 0.4 2.7e+02 2.5 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat CRS1_YhbY PF01985.16 KHN70537.1 - 0.051 13.5 2.1 1.6 8.8 0.1 3.5 2 2 2 4 4 4 0 CRS1 / YhbY (CRM) domain zf-C2H2_4 PF13894.1 KHN70538.1 - 5.3e-07 29.5 6.3 0.019 15.2 1.8 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KHN70538.1 - 0.0017 18.5 11.6 0.0079 16.4 3.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KHN70538.1 - 0.015 15.5 1.8 0.015 15.5 1.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Ribosomal_L1 PF00687.16 KHN70539.1 - 4.3e-23 81.8 2.4 5.4e-23 81.5 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family YonK PF09642.5 KHN70540.1 - 0.03 14.0 0.2 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 YonK protein Aa_trans PF01490.13 KHN70541.1 - 1.3e-55 188.5 35.0 1.5e-55 188.3 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KHN70541.1 - 4e-07 29.1 14.9 4e-07 29.1 10.3 1.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Peptidase_C65 PF10275.4 KHN70542.1 - 1.1e-26 93.6 0.6 1.5e-26 93.2 0.4 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Gemini_AL3 PF01407.12 KHN70542.1 - 0.099 12.1 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Geminivirus AL3 protein CPG4 PF15481.1 KHN70542.1 - 0.82 10.0 4.8 0.49 10.7 0.4 2.2 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 Fcf1 PF04900.7 KHN70543.1 - 3.1e-33 113.8 0.9 2e-32 111.2 0.1 2.0 2 0 0 2 2 2 1 Fcf1 PQQ_3 PF13570.1 KHN70544.1 - 0.0072 16.5 0.4 0.081 13.2 0.0 2.8 3 0 0 3 3 3 1 PQQ-like domain Coatomer_WDAD PF04053.9 KHN70544.1 - 0.15 10.8 5.4 0.51 9.0 3.1 2.0 1 1 1 2 2 2 0 Coatomer WD associated region FAT PF02259.18 KHN70545.1 - 5.8e-25 88.0 0.1 1.3e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 FAT domain TPR_11 PF13414.1 KHN70545.1 - 0.065 12.8 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 KHN70545.1 - 0.077 12.9 0.0 0.38 10.7 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Inos-1-P_synth PF01658.12 KHN70546.1 - 0.02 14.7 0.1 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Marek_SORF3 PF07153.6 KHN70546.1 - 0.022 13.4 0.1 0.023 13.3 0.1 1.1 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein DUF2171 PF09939.4 KHN70546.1 - 0.11 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) TAFII55_N PF04658.8 KHN70547.1 - 4.8e-28 97.6 3.8 4.8e-28 97.6 2.6 2.5 2 1 0 2 2 2 1 TAFII55 protein conserved region DUF4368 PF14287.1 KHN70547.1 - 0.05 13.4 2.2 0.11 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) XkdW PF09636.5 KHN70547.1 - 0.32 10.8 2.9 0.5 10.2 1.3 1.8 1 1 0 1 1 1 0 XkdW protein DUF3090 PF11290.3 KHN70547.1 - 2.8 7.3 6.1 9.1 5.7 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) Bromo_TP PF07524.8 KHN70548.1 - 3e-07 30.0 0.0 5.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TFIIB PF00382.14 KHN70549.1 - 2e-26 91.5 0.0 5.5e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KHN70549.1 - 6.7e-08 31.7 1.4 3.7e-07 29.3 0.7 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding BRF1 PF07741.8 KHN70549.1 - 9e-08 32.2 4.1 1.8e-06 28.1 2.9 2.4 1 1 0 1 1 1 1 Brf1-like TBP-binding domain HTH_38 PF13936.1 KHN70549.1 - 0.0018 17.7 0.2 0.0044 16.5 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_24 PF13412.1 KHN70549.1 - 0.0062 15.8 1.6 0.029 13.7 0.1 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 KHN70549.1 - 0.032 13.7 4.2 0.055 13.0 0.1 2.6 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 KHN70549.1 - 0.054 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_11 PF08279.7 KHN70549.1 - 0.072 12.7 0.1 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.1 KHN70549.1 - 0.088 12.0 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.11 KHN70549.1 - 0.13 11.6 0.4 0.38 10.1 0.3 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 MarR_2 PF12802.2 KHN70549.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 MarR family Synaptobrevin PF00957.16 KHN70550.1 - 4.6e-11 42.1 0.1 5e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF2407_C PF13373.1 KHN70550.1 - 0.029 14.3 0.1 0.033 14.1 0.0 1.0 1 0 0 1 1 1 0 DUF2407 C-terminal domain VIT1 PF01988.14 KHN70550.1 - 0.029 13.8 1.5 0.053 12.9 1.1 1.4 1 1 0 1 1 1 0 VIT family V_ATPase_I PF01496.14 KHN70550.1 - 0.07 10.9 0.4 0.074 10.8 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4047 PF13256.1 KHN70550.1 - 0.11 12.4 0.9 0.14 12.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Rhabdo_glycop PF00974.13 KHN70550.1 - 0.12 10.5 0.0 0.13 10.4 0.0 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Xpo1 PF08389.7 KHN70551.1 - 0.04 13.8 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Exportin 1-like protein Ribosomal_L10 PF00466.15 KHN70552.1 - 7e-06 25.8 1.0 1.2e-05 25.1 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L10 Avirulence PF03377.8 KHN70552.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA DHH PF01368.15 KHN70554.1 - 3.3e-06 26.7 0.6 1.2e-05 24.9 0.4 2.0 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 KHN70554.1 - 0.0058 16.8 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 DHHA2 domain CBFD_NFYB_HMF PF00808.18 KHN70555.1 - 5.6e-17 61.5 0.1 1.2e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KHN70555.1 - 1.2e-08 34.9 0.3 1.9e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Metallophos PF00149.23 KHN70556.1 - 5e-31 107.6 0.4 6.9e-31 107.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 KHN70556.1 - 6.6e-06 25.6 2.1 2.5e-05 23.8 0.2 2.2 1 1 1 2 2 2 2 TPR repeat Metallophos_2 PF12850.2 KHN70556.1 - 1.8e-05 24.6 0.1 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_12 PF13424.1 KHN70556.1 - 0.0032 17.3 1.8 0.061 13.2 0.1 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KHN70556.1 - 0.0058 16.4 0.3 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KHN70556.1 - 0.0062 16.4 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat MAP65_ASE1 PF03999.7 KHN70558.1 - 0.00013 20.7 31.1 0.028 13.0 21.3 3.1 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF3287 PF11690.3 KHN70558.1 - 0.057 13.5 0.1 0.057 13.5 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3287) Syntaxin-6_N PF09177.6 KHN70558.1 - 1.8 9.0 8.9 9.4 6.7 0.0 3.9 4 1 1 5 5 5 0 Syntaxin 6, N-terminal SPASM PF13186.1 KHN70559.1 - 0.098 13.0 1.1 0.67 10.3 0.0 2.7 3 0 0 3 3 3 0 Iron-sulfur cluster-binding domain MMR_HSR1 PF01926.18 KHN70560.1 - 3.1e-17 62.6 0.0 5.8e-17 61.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 KHN70560.1 - 4.3e-17 61.6 0.0 8.3e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 KHN70560.1 - 6.6e-10 38.4 0.0 2.8e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 KHN70560.1 - 0.002 16.9 0.1 0.0056 15.4 0.1 1.6 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 KHN70560.1 - 0.013 16.0 0.0 0.36 11.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 KHN70560.1 - 0.018 14.9 0.3 2.6 7.8 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Syntaxin PF00804.20 KHN70560.1 - 0.087 12.9 0.5 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Syntaxin vATP-synt_E PF01991.13 KHN70561.1 - 1.8e-19 69.7 20.0 1.4e-18 66.8 13.9 2.1 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit CsgE PF10627.4 KHN70561.1 - 0.0021 17.8 0.6 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Curli assembly protein CsgE DUF3335 PF11814.3 KHN70561.1 - 0.018 14.2 1.8 0.085 11.9 0.0 2.3 1 1 1 2 2 2 0 Peptidase_C39 like family DUF2621 PF11084.3 KHN70561.1 - 0.036 13.7 0.7 0.06 13.0 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2621) OmpH PF03938.9 KHN70561.1 - 0.12 12.3 4.3 0.16 11.9 3.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HAUS6_N PF14661.1 KHN70561.1 - 0.35 10.1 5.3 0.41 9.9 3.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RNA_pol_Rpb1_5 PF04998.12 KHN70561.1 - 1.6 7.9 5.2 2.1 7.5 3.6 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Actin PF00022.14 KHN70562.1 - 3.6e-13 48.7 0.0 2.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Actin CPSF100_C PF13299.1 KHN70563.1 - 9.6e-06 25.8 0.7 1.9e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KHN70563.1 - 1.3e-05 25.1 0.0 3.7e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain DUF2108 PF09881.4 KHN70563.1 - 0.059 13.2 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) DUF694 PF05107.7 KHN70563.1 - 0.25 10.5 1.7 0.4 9.8 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF694) MAGE PF01454.14 KHN70564.1 - 3.5e-05 23.2 0.9 0.00079 18.8 0.6 2.1 1 1 0 1 1 1 1 MAGE family TPR_12 PF13424.1 KHN70565.1 - 3.7e-05 23.5 0.3 0.00024 20.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KHN70565.1 - 0.00029 20.4 0.9 0.55 9.9 0.3 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KHN70565.1 - 0.0024 17.4 0.8 0.014 14.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat CarD_CdnL_TRCF PF02559.11 KHN70565.1 - 0.027 14.4 0.0 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 CarD-like/TRCF domain TPR_2 PF07719.12 KHN70565.1 - 0.029 14.2 0.1 2 8.5 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KHN70565.1 - 0.054 12.7 0.0 0.15 11.2 0.0 1.9 1 0 0 1 1 1 0 SHNi-TPR TPR_8 PF13181.1 KHN70565.1 - 0.074 12.8 0.4 0.32 10.8 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 KHN70565.1 - 0.077 13.3 0.0 3.7 7.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat eRF1_2 PF03464.10 KHN70566.1 - 9.8e-33 113.3 0.2 1.6e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KHN70566.1 - 7.6e-30 103.4 0.1 1.7e-29 102.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KHN70566.1 - 6.7e-20 71.0 0.0 2.2e-19 69.3 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 1 Myb_DNA-binding PF00249.26 KHN70567.1 - 9.2e-10 38.4 0.2 2.2e-09 37.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KHN70567.1 - 4.2e-07 29.9 0.1 2e-06 27.8 0.1 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.12 KHN70567.1 - 2.8e-05 24.1 0.0 7.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Peptidase_S49 PF01343.13 KHN70567.1 - 0.041 13.6 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 Bap31 PF05529.7 KHN70568.1 - 5.1e-29 101.1 18.3 5.1e-29 101.1 12.7 2.3 2 1 0 2 2 2 1 B-cell receptor-associated protein 31-like GAS PF13851.1 KHN70568.1 - 0.0073 15.5 11.2 0.0092 15.1 7.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.1 KHN70568.1 - 0.042 13.7 1.2 0.081 12.8 0.8 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1866 PF08952.6 KHN70568.1 - 0.084 12.4 0.2 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DASH_Dad3 PF08656.5 KHN70568.1 - 0.18 11.5 2.5 0.62 9.7 0.5 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad3 Atg14 PF10186.4 KHN70568.1 - 1.7 7.5 7.0 2.1 7.2 4.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KHN70568.1 - 7.3 6.1 8.7 1.8 8.1 2.3 2.3 1 1 1 2 2 2 0 Septum formation initiator DNA_pol_E_B PF04042.11 KHN70569.1 - 5.4e-14 51.9 0.7 1.5e-13 50.4 0.4 1.7 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PGK PF00162.14 KHN70570.1 - 5.8e-82 275.2 0.0 7.1e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase AMP-binding PF00501.23 KHN70571.1 - 9.1e-79 264.7 0.0 1.1e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KHN70571.1 - 1.3e-11 45.2 0.0 2.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DNA_mis_repair PF01119.14 KHN70572.1 - 1.6e-23 82.4 0.2 3.1e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KHN70572.1 - 7.5e-13 48.3 0.1 1.9e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KHN70572.1 - 9.6e-09 34.9 0.2 3.4e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Autophagy_act_C PF03987.10 KHN70572.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain Proteasome PF00227.21 KHN70573.1 - 1.6e-24 86.2 0.2 2.1e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit dUTPase PF00692.14 KHN70574.1 - 3.2e-13 49.2 0.0 9.1e-13 47.7 0.0 1.6 1 1 0 1 1 1 1 dUTPase RNA_pol_L_2 PF13656.1 KHN70575.1 - 8.4e-19 66.7 0.3 9.7e-19 66.5 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KHN70575.1 - 0.0049 15.9 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NAD_Gly3P_dh_N PF01210.18 KHN70576.1 - 4.9e-38 130.3 0.0 6.8e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KHN70576.1 - 2e-37 128.2 0.0 2.9e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Semialdhyde_dh PF01118.19 KHN70576.1 - 0.021 15.1 0.0 0.098 12.9 0.0 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PMM PF03332.8 KHN70577.1 - 8.6e-92 306.6 4.0 1e-91 306.4 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KHN70577.1 - 2e-08 34.1 0.3 3.2e-08 33.4 0.2 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 KHN70577.1 - 5.6e-05 22.5 0.0 0.0044 16.3 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Ribosomal_S3Ae PF01015.13 KHN70578.1 - 9.1e-52 175.2 5.6 1e-51 175.0 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Flavodoxin_1 PF00258.20 KHN70579.1 - 4.4e-21 75.3 0.0 2.2e-19 69.8 0.0 2.4 1 1 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 KHN70579.1 - 1.4e-10 41.0 0.0 9.9e-10 38.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KHN70579.1 - 3.1e-06 27.7 0.0 1.4e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF273 PF03314.9 KHN70579.1 - 0.01 15.1 0.0 0.29 10.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF273 DsrC PF04358.8 KHN70579.1 - 0.03 14.5 0.0 0.17 12.1 0.0 2.3 1 1 0 1 1 1 0 DsrC like protein DUF2023 PF09633.5 KHN70580.1 - 0.0038 17.1 0.5 0.029 14.2 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2023) RNA_helicase PF00910.17 KHN70580.1 - 0.013 15.6 0.5 0.018 15.2 0.3 1.2 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.27 KHN70581.1 - 1.1e-24 85.3 10.2 1.3e-09 37.5 0.3 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DZR PF12773.2 KHN70583.1 - 0.00077 19.2 18.8 0.011 15.4 6.9 2.7 1 1 1 2 2 2 2 Double zinc ribbon zf-ribbon_3 PF13248.1 KHN70583.1 - 0.032 13.4 19.0 0.12 11.5 1.2 3.9 3 1 2 5 5 5 0 zinc-ribbon domain DUF35_N PF12172.3 KHN70583.1 - 0.039 13.8 9.4 0.28 11.1 0.9 3.4 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2296 PF10058.4 KHN70583.1 - 0.06 13.0 1.5 0.06 13.0 1.0 3.4 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) PolC_DP2 PF03833.8 KHN70583.1 - 0.5 7.9 8.2 0.73 7.4 5.7 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Chordopox_RPO7 PF05864.7 KHN70583.1 - 2.7 8.1 5.6 14 5.9 0.6 2.8 2 1 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Ribosomal_L32p PF01783.18 KHN70583.1 - 5.1 7.3 6.1 36 4.6 0.0 2.9 2 1 1 3 3 3 0 Ribosomal L32p protein family Zn_Tnp_IS1595 PF12760.2 KHN70583.1 - 7.6 6.4 24.0 0.14 12.0 2.6 4.2 1 1 3 4 4 4 0 Transposase zinc-ribbon domain WD40 PF00400.27 KHN70584.1 - 7.9e-20 69.9 16.2 1.1e-05 25.1 0.0 7.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.3 KHN70584.1 - 0.00099 17.3 1.4 0.15 10.1 0.0 3.3 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Utp12 PF04003.7 KHN70584.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family PPI_Ypi1 PF07491.6 KHN70585.1 - 6.6e-13 48.0 3.4 7.6e-13 47.8 2.4 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor OKR_DC_1_N PF03709.10 KHN70585.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.0 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain SWIM PF04434.12 KHN70586.1 - 4.6e-05 22.7 1.2 0.00012 21.4 0.8 1.7 1 0 0 1 1 1 1 SWIM zinc finger HEPPP_synt_1 PF07307.6 KHN70588.1 - 0.12 11.7 4.9 0.98 8.8 0.4 2.6 3 0 0 3 3 3 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pyr_excise PF03013.9 KHN70590.1 - 0.08 12.7 0.8 0.18 11.5 0.1 1.8 1 1 1 2 2 2 0 Pyrimidine dimer DNA glycosylase Arf PF00025.16 KHN70592.1 - 2.5e-37 127.8 0.0 3e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KHN70592.1 - 4.7e-12 45.5 0.0 6.5e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KHN70592.1 - 1.3e-11 45.0 0.0 2.5e-11 44.0 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Ras PF00071.17 KHN70592.1 - 3e-11 42.9 0.1 4.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KHN70592.1 - 2.5e-10 40.3 0.1 3.7e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KHN70592.1 - 3.3e-09 36.2 0.0 5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KHN70592.1 - 1.9e-08 33.4 0.8 2.4e-05 23.1 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 KHN70592.1 - 4.8e-08 32.6 1.0 3.9e-06 26.4 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KHN70592.1 - 2.7e-05 23.4 0.5 6.2e-05 22.3 0.4 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 KHN70592.1 - 8.7e-05 22.0 0.2 0.0097 15.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KHN70592.1 - 0.012 15.1 0.1 0.04 13.3 0.1 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KHN70592.1 - 0.03 13.8 0.1 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 KHN70592.1 - 0.066 12.5 0.2 0.41 10.0 0.0 2.0 1 1 0 2 2 2 0 Thymidylate kinase UBA_2 PF08587.6 KHN70592.1 - 0.079 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF258 PF03193.11 KHN70592.1 - 0.11 11.7 0.1 0.15 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KHN70592.1 - 0.12 12.5 0.1 0.79 9.9 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Methylase_S PF01420.14 KHN70593.1 - 0.83 9.6 3.3 4.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Type I restriction modification DNA specificity domain Kinesin PF00225.18 KHN70595.1 - 1.7e-84 283.3 3.4 1.7e-84 283.3 2.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain WD40 PF00400.27 KHN70595.1 - 1.8e-05 24.4 11.3 0.0091 15.8 0.5 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat Herpes_BLRF2 PF05812.7 KHN70595.1 - 0.0036 17.1 11.0 0.027 14.2 1.2 3.0 1 1 1 2 2 2 2 Herpesvirus BLRF2 protein Mto2_bdg PF12808.2 KHN70595.1 - 0.47 10.6 4.3 5.8 7.0 0.6 3.0 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Kinesin-relat_1 PF12711.2 KHN70595.1 - 0.59 10.5 14.9 0.16 12.3 3.9 3.1 2 1 1 3 3 3 0 Kinesin motor Microtub_assoc PF07989.6 KHN70595.1 - 4.7 7.0 16.9 0.054 13.3 5.6 2.3 3 0 0 3 3 3 0 Microtubule associated DUF2339 PF10101.4 KHN70596.1 - 0.00089 17.6 4.2 0.0013 17.1 2.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Fusion_gly_K PF01621.12 KHN70596.1 - 0.0071 15.4 8.1 0.011 14.7 3.9 2.2 1 1 0 2 2 2 1 Cell fusion glycoprotein K Cytochrom_B_N PF00033.14 KHN70596.1 - 0.95 8.7 6.8 4.6 6.5 0.2 2.7 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB LrgB PF04172.11 KHN70596.1 - 1.9 7.5 12.9 5.6 6.0 7.0 2.6 2 1 0 2 2 2 0 LrgB-like family NfeD PF01957.13 KHN70596.1 - 7.5 6.6 9.8 6 6.9 0.0 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding