# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Prion PF00377.18 EQB59658.1 - 0.00057 19.7 0.5 0.00073 19.4 0.5 1.2 1 0 0 1 1 1 1 Prion/Doppel alpha-helical domain TypeIII_RM_meth PF12564.8 EQB59658.1 - 0.012 15.7 4.5 0.012 15.7 4.5 2.0 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit SPX PF03105.19 EQB59658.1 - 0.075 12.9 0.7 0.075 12.9 0.7 2.0 1 1 0 2 2 2 0 SPX domain DUF1581 PF07619.11 EQB59658.1 - 0.15 12.2 0.4 0.39 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) Helicase_C PF00271.31 EQB59659.1 - 3.6e-15 56.3 0.3 4.9e-15 55.8 0.3 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FGase PF05013.12 EQB59664.1 - 0.47 10.6 1.5 7.8 6.6 0.6 2.2 1 1 1 2 2 2 0 N-formylglutamate amidohydrolase Trypan_PARP PF05887.11 EQB59665.1 - 0.017 15.1 1.2 0.019 15.0 1.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Hemolysin_N PF12563.8 EQB59667.1 - 0.0069 16.0 0.1 0.0077 15.8 0.1 1.1 1 0 0 1 1 1 1 Hemolytic toxin N terminal IncFII_repA PF02387.15 EQB59669.1 - 0.13 11.5 0.2 0.16 11.2 0.2 1.0 1 0 0 1 1 1 0 IncFII RepA protein family TB2_DP1_HVA22 PF03134.19 EQB59673.1 - 3.2e-17 62.2 0.5 3.2e-17 62.2 0.5 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family dCMP_cyt_deam_1 PF00383.23 EQB59674.1 - 2.8e-17 62.5 1.5 1.1e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EQB59674.1 - 3.2e-15 56.1 0.8 3e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 MafB19-like deaminase Herpes_BLLF1 PF05109.13 EQB59674.1 - 0.032 12.2 3.2 0.043 11.8 3.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF5481 PF17578.2 EQB59676.1 - 0.017 15.5 0.2 0.044 14.2 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5481) DUF1098 PF06497.11 EQB59676.1 - 0.022 15.2 0.2 0.3 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) zf-B_box PF00643.24 EQB59677.1 - 6.3e-10 39.0 17.2 1.9e-07 31.1 1.4 2.5 2 0 0 2 2 2 2 B-box zinc finger Clat_adaptor_s PF01217.20 EQB59680.1 - 5.1e-18 65.4 11.8 2.9e-17 62.9 11.8 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Acetyltransf_19 PF18015.1 EQB59680.1 - 0.057 13.6 2.5 1.4 9.1 0.3 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain TFCD_C PF12612.8 EQB59685.1 - 0.0062 16.4 0.6 0.023 14.6 0.1 1.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal zf-C4H2 PF10146.9 EQB59685.1 - 0.033 14.5 0.2 0.049 14.0 0.2 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Acetyltransf_11 PF13720.6 EQB59685.1 - 0.15 12.6 1.1 0.28 11.7 0.2 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Nucleopor_Nup85 PF07575.13 EQB59686.1 - 0.00075 18.2 0.2 0.00083 18.1 0.2 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Cbl_N2 PF02761.14 EQB59686.1 - 0.0043 17.7 0.5 0.006 17.3 0.4 1.4 1 1 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain KASH_CCD PF14662.6 EQB59686.1 - 0.012 15.5 4.7 0.22 11.3 4.7 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PTPA PF03095.15 EQB59686.1 - 0.021 14.3 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein Coatomer_g_Cpla PF16381.5 EQB59686.1 - 0.074 13.2 0.5 0.1 12.8 0.5 1.2 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform PDH PF02153.17 EQB59686.1 - 0.14 11.1 1.6 0.26 10.3 1.6 1.5 1 1 0 1 1 1 0 Prephenate dehydrogenase DUF677 PF05055.12 EQB59686.1 - 0.15 10.9 4.1 0.17 10.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Arf PF00025.21 EQB59688.1 - 9.2e-41 139.2 0.1 1.1e-40 138.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EQB59688.1 - 2e-15 56.8 0.1 2.6e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB59688.1 - 1.5e-14 54.2 0.1 2.7e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EQB59688.1 - 3.5e-09 36.4 0.1 4.4e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EQB59688.1 - 2.7e-08 33.5 0.1 4.5e-08 32.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EQB59688.1 - 2.8e-08 33.3 7.0 4e-07 29.5 1.9 2.6 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EQB59688.1 - 3.1e-05 24.0 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 EQB59688.1 - 0.0018 18.0 0.2 0.0073 16.1 0.0 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) GTP_EFTU PF00009.27 EQB59688.1 - 0.012 15.2 0.5 0.059 12.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EQB59688.1 - 0.048 13.8 0.1 0.27 11.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain LamB_YcsF PF03746.16 EQB59688.1 - 0.085 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 LamB/YcsF family RsgA_GTPase PF03193.16 EQB59688.1 - 0.21 11.5 1.3 14 5.5 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase LAP1C PF05609.12 EQB59690.1 - 1.1 8.3 11.9 1.4 8.0 11.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Arteri_Gl PF00951.18 EQB59692.1 - 0.035 13.9 2.1 0.064 13.1 2.1 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein PCI PF01399.27 EQB59693.1 - 2.2e-11 44.2 4.3 4.2e-11 43.3 1.7 2.5 1 1 1 2 2 2 1 PCI domain RPN6_N PF18055.1 EQB59693.1 - 2.5e-08 34.3 1.9 4e-08 33.6 0.2 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain RPN7 PF10602.9 EQB59693.1 - 0.0025 17.6 2.9 0.036 13.8 2.9 2.3 1 1 0 1 1 1 1 26S proteasome subunit RPN7 RIX1 PF08167.12 EQB59693.1 - 0.026 14.3 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis TPR_12 PF13424.6 EQB59693.1 - 0.029 14.6 0.1 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DDRGK PF09756.9 EQB59693.1 - 0.048 13.3 5.7 0.084 12.5 5.2 1.6 1 1 0 1 1 1 0 DDRGK domain TPR_2 PF07719.17 EQB59693.1 - 0.12 12.6 2.1 6.3 7.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ssu72 PF04722.13 EQB59694.1 - 5.9e-57 192.3 2.1 6.8e-57 192.1 2.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein gag-asp_proteas PF13975.6 EQB59695.1 - 4.8e-07 30.3 0.1 4.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EQB59695.1 - 0.00028 21.5 0.1 0.0011 19.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 EQB59695.1 - 0.00038 20.2 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease SNF2_N PF00176.23 EQB59696.1 - 5e-25 88.0 0.0 1.3e-24 86.6 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EQB59696.1 - 5e-05 23.4 0.0 0.00027 21.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EQB59696.1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain DEAD PF00270.29 EQB59696.1 - 0.0092 15.8 0.0 0.053 13.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF5607 PF18355.1 EQB59696.1 - 0.037 14.5 0.0 5.2 7.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5607) SWI2_SNF2 PF18766.1 EQB59696.1 - 0.057 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase CSN7a_helixI PF18392.1 EQB59696.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Helicase_C PF00271.31 EQB59697.1 - 6.6e-11 42.5 0.0 9.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DnaJ PF00226.31 EQB59699.1 - 1.2e-10 41.4 0.8 1.2e-10 41.4 0.8 1.7 2 0 0 2 2 2 1 DnaJ domain RRG8 PF17068.5 EQB59699.1 - 0.0023 17.4 2.2 0.0024 17.3 2.2 1.1 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial Yuri_gagarin PF15934.5 EQB59699.1 - 0.0065 16.3 1.1 0.0066 16.3 1.1 1.2 1 0 0 1 1 1 1 Yuri gagarin ARL2_Bind_BART PF11527.8 EQB59699.1 - 0.024 14.8 1.5 0.036 14.2 1.5 1.4 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART PuR_N PF09182.10 EQB59699.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal DUF2856 PF11043.8 EQB59699.1 - 0.37 10.9 3.2 0.72 10.0 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2856) Nbs1_C PF08599.10 EQB59699.1 - 0.92 9.7 4.4 0.14 12.3 0.6 1.7 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 MIEAP PF16026.5 EQB59701.1 - 0.023 14.9 1.0 0.027 14.7 1.0 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein RNA_pol_Rpb1_5 PF04998.17 EQB59701.1 - 1 8.8 6.0 1.6 8.1 6.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mitofilin PF09731.9 EQB59701.1 - 8.5 5.1 12.5 5 5.8 10.6 1.5 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Nop14 PF04147.12 EQB59703.1 - 0.00064 18.1 5.0 0.00081 17.8 5.0 1.1 1 0 0 1 1 1 1 Nop14-like family Presenilin PF01080.17 EQB59703.1 - 0.24 10.1 7.5 0.28 9.9 7.5 1.1 1 0 0 1 1 1 0 Presenilin ATP11 PF06644.11 EQB59703.1 - 1.2 8.9 6.0 1.5 8.6 6.0 1.1 1 0 0 1 1 1 0 ATP11 protein Paramyxo_ncap PF00973.19 EQB59703.1 - 1.6 7.5 7.8 2 7.2 7.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HCO3_cotransp PF00955.21 EQB59703.1 - 2.3 6.9 4.1 3.1 6.5 4.1 1.3 1 0 0 1 1 1 0 HCO3- transporter family DUF4407 PF14362.6 EQB59703.1 - 4.2 6.6 7.1 5.6 6.2 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 EQB59704.1 - 7.7e-15 55.8 6.7 4.4e-13 50.0 2.7 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit CPP1-like PF11833.8 EQB59705.1 - 0.17 11.5 2.6 0.32 10.6 2.5 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ATP-synt_C PF00137.21 EQB59705.1 - 0.22 11.9 8.1 4.5 7.7 5.5 2.2 2 0 0 2 2 2 0 ATP synthase subunit C CbtB PF09489.10 EQB59705.1 - 0.6 10.3 3.3 0.84 9.8 0.9 2.4 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtB) AAA_24 PF13479.6 EQB59706.1 - 0.0011 18.7 0.1 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain CH PF00307.31 EQB59707.1 - 6.2e-12 45.7 0.1 8.7e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Phage_tail_2 PF06199.11 EQB59707.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail tube protein DUF3010 PF11215.8 EQB59708.1 - 0.082 13.2 1.0 0.35 11.2 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3010) Pkinase PF00069.25 EQB59709.1 - 1.6e-65 221.1 0.3 1.8e-65 221.0 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB59709.1 - 3.5e-29 101.9 0.3 4.5e-29 101.5 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB59709.1 - 0.00015 21.2 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EQB59709.1 - 0.00064 18.8 0.3 0.00099 18.1 0.3 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EQB59709.1 - 0.055 12.2 0.2 0.094 11.5 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EQB59709.1 - 0.2 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family BsuBI_PstI_RE PF06616.11 EQB59710.1 - 0.05 12.9 1.4 0.55 9.5 1.0 2.2 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease domain Peptidase_M16 PF00675.20 EQB59711.1 - 1.2e-35 122.7 0.1 1.8e-34 118.8 0.0 2.7 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EQB59711.1 - 1.1e-05 24.9 0.4 3.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EQB59711.1 - 0.00091 19.3 0.2 0.016 15.2 0.2 2.5 1 1 0 1 1 1 1 Peptidase M16 inactive domain Tubulin PF00091.25 EQB59712.1 - 1.4e-68 231.0 0.0 2.5e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EQB59712.1 - 5.2e-40 136.5 0.1 8.5e-40 135.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EQB59712.1 - 1.8e-05 25.0 0.0 3.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EQB59712.1 - 0.064 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin like RNB PF00773.19 EQB59713.1 - 4.1e-58 197.2 0.1 4.1e-58 197.2 0.1 2.3 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EQB59713.1 - 1.6e-17 63.2 0.0 3.2e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 EQB59713.1 - 0.0018 18.0 2.1 0.0046 16.7 2.1 1.6 1 1 0 1 1 1 1 Rrp44-like cold shock domain DUF1938 PF09153.10 EQB59713.1 - 0.0026 17.8 0.5 0.045 13.8 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1938) DUF1765 PF08578.10 EQB59713.1 - 0.2 12.1 4.5 0.27 11.7 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1765) YxiJ PF14176.6 EQB59713.1 - 0.67 10.5 9.2 0.2 12.2 4.6 2.5 2 1 0 2 2 2 0 YxiJ-like protein RNB PF00773.19 EQB59714.1 - 1.3e-26 93.7 0.4 2.2e-26 93.0 0.4 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 EQB59714.1 - 0.0015 18.5 0.2 0.0074 16.2 0.2 2.1 1 1 0 1 1 1 1 S1 domain CDC37_C PF08564.10 EQB59714.1 - 0.096 12.8 0.5 2 8.6 0.1 2.7 3 0 0 3 3 3 0 Cdc37 C terminal domain tRNA-synt_1g PF09334.11 EQB59715.1 - 2.8e-129 431.3 4.6 3.9e-129 430.8 4.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EQB59715.1 - 4e-05 22.1 1.5 0.00084 17.7 0.0 3.0 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) zf-ribbon_3 PF13248.6 EQB59715.1 - 0.048 13.1 6.4 0.093 12.2 3.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain RNA_pol_Rpb1_3 PF04983.18 EQB59715.1 - 0.15 12.0 3.8 2.4 8.1 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 Ribosomal_L34e PF01199.18 EQB59716.1 - 4.6e-29 100.6 6.6 5.4e-29 100.3 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Mut7-C PF01927.16 EQB59716.1 - 0.014 15.5 0.7 0.018 15.1 0.7 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain LRR_8 PF13855.6 EQB59717.1 - 4.2e-15 55.2 44.3 1.2e-06 28.2 11.5 5.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EQB59717.1 - 7.7e-15 54.8 51.8 0.0002 21.7 5.9 5.9 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EQB59717.1 - 0.0072 16.3 9.5 0.0072 16.3 9.5 2.9 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 EQB59717.1 - 0.02 14.9 0.2 0.96 9.5 0.0 3.0 2 1 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 EQB59717.1 - 2.5 8.4 21.9 3.3 8.0 0.2 6.6 6 0 0 6 6 6 0 Leucine Rich repeat Acyltransferase PF01553.21 EQB59718.1 - 5e-15 55.3 0.1 7e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase RRM_1 PF00076.22 EQB59721.1 - 3.2e-24 84.5 7.2 1e-15 57.3 0.2 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EQB59721.1 - 0.0016 18.5 0.2 0.24 11.5 0.0 2.9 1 1 1 2 2 2 2 RNA recognition motif RRM_1 PF00076.22 EQB59722.1 - 2.5e-08 33.6 0.0 3.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thymidylate_kin PF02223.17 EQB59722.1 - 0.079 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase DUF4187 PF13821.6 EQB59722.1 - 0.14 12.0 1.2 0.33 10.8 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) RST PF12174.8 EQB59723.1 - 0.7 9.9 3.9 0.49 10.4 0.6 2.5 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Attractin PF08037.11 EQB59723.1 - 1.1 9.2 6.5 8.7 6.4 6.4 2.3 1 1 0 1 1 1 0 Attractin family Zip PF02535.22 EQB59724.1 - 0.16 11.1 0.2 0.23 10.7 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HCO3_cotransp PF00955.21 EQB59724.1 - 0.73 8.6 2.6 1.1 8.0 2.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family CENP-F_leu_zip PF10473.9 EQB59725.1 - 0.044 13.8 13.4 0.57 10.2 2.1 2.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Toxin_10 PF05431.11 EQB59725.1 - 0.094 12.2 1.3 8.3 5.8 0.1 2.4 1 1 0 2 2 2 0 Insecticidal Crystal Toxin, P42 CCD PF07860.11 EQB59725.1 - 0.16 12.0 0.0 23 5.0 0.0 2.2 2 0 0 2 2 2 0 WisP family C-Terminal Region FOXP-CC PF16159.5 EQB59725.1 - 0.29 11.8 3.0 21 5.9 0.2 2.6 2 2 0 2 2 2 0 FOXP coiled-coil domain TMP PF05017.14 EQB59725.1 - 0.39 11.5 1.6 60 5.0 0.1 2.8 2 0 0 2 2 2 0 TMP repeat NusG_II PF07009.11 EQB59729.1 - 1.3 9.2 6.3 0.77 10.0 1.8 2.4 1 1 0 2 2 2 0 NusG domain II Cadherin_pro PF08758.11 EQB59732.1 - 0.7 10.1 2.8 2.1 8.6 0.1 2.6 2 1 1 3 3 3 0 Cadherin prodomain like GET2 PF08690.10 EQB59733.1 - 2.4 7.7 3.9 0.76 9.4 0.2 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 Rib_5-P_isom_A PF06026.14 EQB59737.1 - 3.7e-36 124.3 0.0 6.9e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EQB59737.1 - 0.015 15.2 0.7 0.3 11.0 0.7 2.1 1 1 0 1 1 1 0 DeoR C terminal sensor domain Sugar-bind PF04198.13 EQB59737.1 - 0.041 13.0 0.0 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 Putative sugar-binding domain DUF1289 PF06945.13 EQB59739.1 - 0.14 12.0 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) PFK PF00365.20 EQB59740.1 - 3.2e-56 190.8 0.1 6.6e-56 189.7 0.1 1.6 1 1 0 1 1 1 1 Phosphofructokinase PFK PF00365.20 EQB59741.1 - 1.1e-56 192.2 0.0 1.8e-56 191.6 0.0 1.3 2 0 0 2 2 2 1 Phosphofructokinase LRR_8 PF13855.6 EQB59742.1 - 7.9e-39 131.2 96.3 1.6e-09 37.3 1.9 7.0 2 1 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EQB59742.1 - 1.3e-27 95.4 74.6 8.2e-07 29.3 1.5 8.1 3 2 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB59742.1 - 4.2e-06 26.4 35.3 0.0029 17.1 8.9 4.3 1 1 4 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 EQB59742.1 - 0.0002 21.2 58.8 4 7.7 0.0 12.2 13 0 0 13 13 13 7 Leucine Rich repeat LRR_1 PF00560.33 EQB59742.1 - 0.0047 17.3 63.4 3.1 8.7 0.6 11.8 12 1 0 12 12 12 4 Leucine Rich Repeat D5_N PF08706.11 EQB59744.1 - 0.00024 21.4 0.1 0.00064 20.0 0.1 1.8 1 0 0 1 1 1 1 D5 N terminal like Herpes_UL52 PF03121.15 EQB59744.1 - 0.0018 18.2 0.7 0.0042 17.0 0.7 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase zf-RVT PF13966.6 EQB59745.1 - 0.008 16.9 2.1 0.017 15.8 0.2 2.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase SusF_SusE PF16411.5 EQB59745.1 - 0.16 12.5 4.1 2.3 8.7 0.2 3.5 2 1 2 4 4 4 0 Outer membrane protein SusF_SusE RRM_1 PF00076.22 EQB59746.1 - 0.017 14.9 0.1 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NCBP3 PF10309.9 EQB59746.1 - 0.019 14.8 1.0 0.056 13.3 1.0 1.8 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 zf-CCCH_2 PF14608.6 EQB59746.1 - 0.21 12.1 4.9 0.38 11.3 4.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger tRNA-synt_2 PF00152.20 EQB59747.1 - 1.3e-82 277.4 0.1 1.9e-82 276.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EQB59747.1 - 0.014 14.9 0.2 4 6.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) TcdB_N PF12918.7 EQB59747.1 - 0.029 14.7 0.1 0.098 13.0 0.1 1.9 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain CDP-OH_P_transf PF01066.21 EQB59748.1 - 9.7e-06 26.3 0.0 9.7e-06 26.3 0.0 3.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HP0268 PF18618.1 EQB59750.1 - 0.04 14.3 0.8 0.099 13.1 0.8 1.6 1 0 0 1 1 1 0 HP0268 HP0268 PF18618.1 EQB59751.1 - 0.05 14.0 0.8 0.14 12.6 0.8 1.7 1 0 0 1 1 1 0 HP0268 CDP-OH_P_transf PF01066.21 EQB59752.1 - 2.8e-13 50.4 2.1 2.8e-13 50.4 2.1 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FeoB_Cyto PF17910.1 EQB59753.1 - 0.031 14.8 1.6 0.031 14.8 1.6 2.9 3 0 0 3 3 3 0 FeoB cytosolic helical domain RVT_1 PF00078.27 EQB59754.1 - 4.7e-10 39.3 0.1 6.9e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EQB59755.1 - 6.4e-06 26.0 1.9 6.4e-06 26.0 1.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 EQB59755.1 - 0.00039 20.0 3.0 0.00076 19.1 3.0 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger ApbA_C PF08546.11 EQB59755.1 - 0.094 12.9 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Myb_DNA-bind_4 PF13837.6 EQB59755.1 - 0.4 11.1 4.5 0.086 13.2 1.1 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RT_RNaseH_2 PF17919.1 EQB59756.1 - 2.1e-12 46.9 0.0 4.4e-12 45.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EQB59756.1 - 9.4e-05 22.6 0.0 0.00032 21.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase IcmF_C PF06744.12 EQB59756.1 - 0.0015 18.2 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal RT_RNaseH_2 PF17919.1 EQB59758.1 - 3.5e-21 75.1 0.0 4.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EQB59758.1 - 1.6e-13 50.8 0.2 4.2e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 EQB59759.1 - 0.0022 18.5 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EQB59759.1 - 0.0026 18.3 0.0 0.0046 17.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 EQB59760.1 - 9.1e-23 80.2 0.0 2.7e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EQB59760.1 - 3.2e-22 78.8 0.0 1e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EQB59760.1 - 2.2e-20 73.2 1.4 1.8e-19 70.2 1.4 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.14 EQB59760.1 - 0.0014 18.4 0.3 0.0037 17.1 0.3 1.7 1 0 0 1 1 1 1 Reverse transcriptase thumb domain SNF2_N PF00176.23 EQB59762.1 - 1.3e-10 40.5 0.8 4.9e-10 38.7 0.8 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 EQB59763.1 - 5.4e-22 78.0 0.1 6.1e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EQB59763.1 - 2.2e-06 27.8 0.0 3.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DBINO PF13892.6 EQB59764.1 - 8.3e-22 78.0 10.3 8.3e-22 78.0 10.3 1.5 2 0 0 2 2 2 1 DNA-binding domain Peptidase_M1 PF01433.20 EQB59764.1 - 0.099 12.2 0.8 0.12 11.9 0.8 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain Taxilin PF09728.9 EQB59766.1 - 0.0014 17.9 1.4 0.0016 17.7 1.4 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein HMMR_N PF15905.5 EQB59766.1 - 0.065 12.7 5.7 0.073 12.5 5.7 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 EQB59766.1 - 0.21 12.0 5.6 0.15 12.4 1.3 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Prenyltransf PF01255.19 EQB59767.1 - 1.2e-40 139.5 0.9 2.2e-25 89.5 0.6 2.5 1 1 1 2 2 2 2 Putative undecaprenyl diphosphate synthase Tubulin-binding PF00418.19 EQB59768.1 - 2.4e-05 24.2 42.2 1.6 8.8 1.3 10.7 8 2 3 11 11 11 8 Tau and MAP protein, tubulin-binding repeat CK2S PF15011.6 EQB59768.1 - 0.037 13.9 15.3 4.1 7.3 0.2 5.1 5 0 0 5 5 5 0 Casein Kinase 2 substrate GvpK PF05121.12 EQB59768.1 - 0.046 13.8 15.5 4.3 7.4 0.2 5.4 6 1 0 6 6 6 0 Gas vesicle protein K Cytochrom_B562 PF07361.11 EQB59768.1 - 0.34 11.6 7.5 22 5.7 0.2 4.1 3 0 0 3 3 3 0 Cytochrome b562 ImpA_N PF06812.12 EQB59768.1 - 4 7.6 7.2 56 3.9 0.2 3.9 3 0 0 3 3 3 0 ImpA, N-terminal, type VI secretion system Tubulin-binding PF00418.19 EQB59769.1 - 0.012 15.6 8.6 0.39 10.8 0.1 4.0 4 0 0 4 4 4 0 Tau and MAP protein, tubulin-binding repeat Prefoldin PF02996.17 EQB59769.1 - 1.1 9.1 9.5 1 9.3 0.3 3.9 1 1 2 4 4 4 0 Prefoldin subunit Homeodomain PF00046.29 EQB59770.1 - 9.6e-11 41.4 0.1 1.6e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EQB59770.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Clathrin PF00637.20 EQB59772.1 - 0.027 14.3 0.9 0.027 14.3 0.9 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS SEP PF08059.13 EQB59776.1 - 6.3e-06 26.7 0.4 1.5e-05 25.4 0.4 1.7 1 0 0 1 1 1 1 SEP domain PRK PF00485.18 EQB59776.1 - 0.94 9.2 6.9 1.1 9.0 6.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF4629 PF15442.6 EQB59777.1 - 0.012 15.8 2.8 0.014 15.6 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) SpdB PF05122.13 EQB59777.1 - 0.04 14.1 0.7 0.074 13.2 0.7 1.4 1 0 0 1 1 1 0 Mobile element transfer protein V_ATPase_I PF01496.19 EQB59779.1 - 1.4e-159 532.6 28.9 4.2e-120 402.1 14.8 3.1 1 1 2 3 3 3 3 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.19 EQB59780.1 - 7.5e-155 517.0 20.1 1.3e-114 383.9 13.3 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family HATPase_c_3 PF13589.6 EQB59781.1 - 5.4e-06 26.3 1.8 7.4e-06 25.8 0.4 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EQB59781.1 - 0.0034 17.9 0.7 0.0034 17.9 0.7 2.1 1 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NIL PF09383.10 EQB59781.1 - 5.7 6.9 7.2 36 4.3 0.2 3.2 3 0 0 3 3 3 0 NIL domain DUF4367 PF14285.6 EQB59782.1 - 7.8 7.0 9.5 33 5.0 3.8 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4367) Polysacc_syn_2C PF08485.10 EQB59783.1 - 0.039 13.7 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal LRR_4 PF12799.7 EQB59784.1 - 4.6e-19 68.2 35.5 4e-06 27.1 5.6 4.4 1 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB59784.1 - 1.6e-18 66.2 22.3 6.1e-06 25.9 3.1 4.3 1 1 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 EQB59784.1 - 2.1e-07 30.5 24.7 0.81 10.5 0.3 7.2 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_9 PF14580.6 EQB59784.1 - 5.1e-07 29.4 14.8 3.7e-05 23.3 5.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat YcxB PF14317.6 EQB59784.1 - 0.0038 16.9 0.8 1.4 8.7 0.0 2.9 3 0 0 3 3 3 2 YcxB-like protein LRR_2 PF07723.13 EQB59784.1 - 0.0049 17.5 1.2 57 4.6 0.0 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat Crystall_4 PF17945.1 EQB59784.1 - 0.063 13.7 0.1 4.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Beta/Gamma crystallin LRR_6 PF13516.6 EQB59784.1 - 0.1 12.7 22.7 3.2 8.0 0.3 7.0 7 0 0 7 7 7 0 Leucine Rich repeat RsmF_methylt_CI PF17126.5 EQB59784.1 - 0.1 12.6 0.2 4.3 7.4 0.0 3.3 1 1 3 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain Lipocalin_3 PF12702.7 EQB59784.1 - 0.14 12.3 3.1 1.1 9.4 0.2 2.4 3 0 0 3 3 3 0 Lipocalin-like DUF3983 PF13137.6 EQB59785.1 - 0.86 9.5 0.1 0.86 9.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3983) RVT_1 PF00078.27 EQB59786.1 - 0.00031 20.3 0.0 0.00043 19.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.6 EQB59787.1 - 1.4e-59 202.2 0.6 1.7e-59 201.9 0.6 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF5094 PF17015.5 EQB59788.1 - 1.9e-37 129.1 12.8 2.2e-37 128.9 12.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) SCVP PF17619.2 EQB59788.1 - 0.29 12.0 2.7 0.26 12.2 0.9 1.8 2 0 0 2 2 2 0 Secreted clade V proteins PH PF00169.29 EQB59789.1 - 2.1e-06 28.2 0.3 2.1e-06 28.2 0.3 2.5 3 1 0 3 3 3 1 PH domain SARAF PF06682.12 EQB59789.1 - 0.13 11.9 3.2 0.19 11.3 3.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis YokU PF14122.6 EQB59790.1 - 0.027 14.4 0.6 0.027 14.4 0.6 2.3 2 0 0 2 2 2 0 YokU-like protein, putative antitoxin PTPA PF03095.15 EQB59791.1 - 2.2e-39 135.7 5.7 1.3e-27 97.1 0.2 3.0 1 1 2 3 3 3 3 Phosphotyrosyl phosphate activator (PTPA) protein PTPA PF03095.15 EQB59792.1 - 8.9e-37 127.2 2.6 1e-27 97.4 0.2 3.0 1 1 2 3 3 3 3 Phosphotyrosyl phosphate activator (PTPA) protein Ribonuc_red_sm PF00268.21 EQB59793.1 - 9.2e-109 363.2 5.3 1.1e-108 362.9 5.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain UCR_UQCRX_QCR9 PF05365.12 EQB59793.1 - 0.3 11.0 2.3 1.3 9.0 0.8 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RicinB_lectin_2 PF14200.6 EQB59798.1 - 0.14 12.9 1.7 3.7 8.3 1.2 2.4 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 EQB59799.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 EQB59800.1 - 0.11 13.3 0.0 0.2 12.4 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like RVT_1 PF00078.27 EQB59802.1 - 3.3e-23 82.4 0.0 8e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1132 PF06575.12 EQB59807.1 - 1.1 9.7 9.6 24 5.4 0.1 4.3 2 2 3 5 5 5 0 Protein of unknown function (DUF1132) Na_trans_assoc PF06512.13 EQB59807.1 - 1.2 9.3 7.2 2.4 8.4 7.2 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Tub PF01167.18 EQB59809.1 - 8.8e-32 110.8 4.7 2.4e-31 109.3 0.3 2.1 1 1 1 2 2 2 2 Tub family Tub PF01167.18 EQB59810.1 - 1.4e-32 113.4 0.7 8.5e-32 110.8 0.3 1.9 1 1 1 2 2 2 1 Tub family Macoilin PF09726.9 EQB59811.1 - 8.4 4.8 45.2 0.0045 15.6 20.8 2.1 2 0 0 2 2 2 0 Macoilin family Ribosomal_S24e PF01282.19 EQB59815.1 - 7e-17 61.1 1.1 7e-17 61.1 1.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S24e Peptidase_G2 PF11962.8 EQB59817.1 - 0.049 13.0 0.1 0.057 12.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain RVT_1 PF00078.27 EQB59819.1 - 7.9e-30 104.0 0.1 1.7e-29 102.9 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EQB59819.1 - 1.1 10.0 3.3 0.69 10.7 0.5 2.1 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 EQB59821.1 - 1e-05 25.3 1.9 1e-05 25.3 1.9 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 EQB59821.1 - 0.0046 16.6 1.2 0.0091 15.7 1.2 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger ApbA_C PF08546.11 EQB59821.1 - 0.092 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Myb_DNA-bind_4 PF13837.6 EQB59821.1 - 0.43 11.0 4.6 0.14 12.5 1.1 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-CCHC PF00098.23 EQB59822.1 - 3.2e-05 23.8 6.4 5.4e-05 23.1 6.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EQB59822.1 - 0.037 13.7 3.8 0.061 13.0 3.8 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EQB59822.1 - 0.26 11.2 2.6 0.53 10.2 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Fer4_13 PF13370.6 EQB59822.1 - 3.2 8.4 6.0 25 5.5 0.1 3.1 3 1 0 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Hydrolase_4 PF12146.8 EQB59825.1 - 0.011 15.1 0.0 0.52 9.5 0.0 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 EQB59825.1 - 0.036 14.0 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 EQB59825.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EQB59825.1 - 0.068 12.8 0.1 0.45 10.1 0.1 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Macoilin PF09726.9 EQB59825.1 - 1.4 7.3 15.2 2.3 6.7 15.2 1.2 1 0 0 1 1 1 0 Macoilin family 8TM_micro PF17028.5 EQB59826.1 - 5.1e-49 167.3 21.8 6.8e-35 121.0 19.2 3.8 1 1 1 2 2 2 2 8TM Microsporidial transmembrane domain KIX_2 PF16987.5 EQB59828.1 - 0.00048 20.1 4.7 0.0012 18.8 4.7 1.7 1 0 0 1 1 1 1 KIX domain CPSase_L_D3 PF02787.19 EQB59829.1 - 0.046 14.1 0.2 0.046 14.1 0.2 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain VPS9 PF02204.18 EQB59831.1 - 1.3e-10 41.4 3.7 8.7e-10 38.8 3.7 2.3 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ribosomal_S5 PF00333.20 EQB59833.1 - 1.7e-24 85.6 2.5 3.2e-24 84.7 2.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EQB59833.1 - 1.1e-23 82.5 0.1 2e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SH2_2 PF14633.6 EQB59834.1 - 2.3e-08 33.7 8.9 7.9e-05 22.2 0.0 2.9 2 1 1 3 3 3 2 SH2 domain UPF0122 PF04297.14 EQB59834.1 - 0.013 15.7 4.5 0.013 15.7 4.5 3.3 4 0 0 4 4 4 0 Putative helix-turn-helix protein, YlxM / p13 like S1 PF00575.23 EQB59834.1 - 0.088 13.2 0.8 0.47 10.8 0.0 2.7 2 0 0 2 2 2 0 S1 RNA binding domain Phage_pRha PF09669.10 EQB59834.1 - 0.2 12.3 2.2 32 5.2 0.5 3.1 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Acetyltransf_1 PF00583.25 EQB59835.1 - 5.5e-10 39.5 0.0 8.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EQB59835.1 - 2.6e-09 37.4 0.0 3.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EQB59835.1 - 5e-09 36.2 0.0 6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EQB59835.1 - 0.00092 19.4 3.1 0.0013 18.9 3.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EQB59835.1 - 0.0026 17.5 2.3 0.0027 17.4 1.3 1.4 1 1 0 1 1 1 1 MOZ/SAS family FR47 PF08445.10 EQB59835.1 - 0.0046 16.9 0.1 0.028 14.4 0.1 2.0 1 1 0 1 1 1 1 FR47-like protein CxC7 PF18866.1 EQB59835.1 - 0.0072 16.4 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 CxC7 like cysteine cluster associated with KDZ transposases Pfk_N PF18468.1 EQB59835.1 - 0.026 14.9 0.3 0.056 13.9 0.3 1.5 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast DCP2 PF05026.13 EQB59836.1 - 4.6e-16 58.9 4.5 9.9e-16 57.8 4.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain HSF_DNA-bind PF00447.17 EQB59838.1 - 1.8e-27 95.8 7.5 5e-27 94.4 7.5 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EQB59838.1 - 0.00033 20.8 0.1 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain DUF2007 PF09413.10 EQB59838.1 - 0.15 12.3 0.6 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Putative prokaryotic signal transducing protein CobA_CobO_BtuR PF02572.15 EQB59838.1 - 0.15 12.3 2.1 1.5 9.1 0.1 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP MSA-2c PF12238.8 EQB59838.1 - 2.1 8.3 7.5 0.55 10.2 3.7 1.8 1 1 0 2 2 2 0 Merozoite surface antigen 2c zinc_ribbon_15 PF17032.5 EQB59839.1 - 1.3e-09 38.6 24.3 2.6e-09 37.7 24.3 1.5 1 1 0 1 1 1 1 zinc-ribbon family Zn-ribbon_8 PF09723.10 EQB59839.1 - 0.015 15.4 8.3 0.099 12.8 2.7 3.9 3 1 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 EQB59839.1 - 0.024 14.6 24.8 0.33 11.0 16.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EQB59839.1 - 0.044 13.2 2.4 0.044 13.2 2.4 4.1 5 0 0 5 5 5 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 EQB59839.1 - 7.7 6.4 29.8 2.9 7.7 2.7 5.1 3 2 1 4 4 4 0 A2L zinc ribbon domain tRNA-synt_2b PF00587.25 EQB59840.1 - 2.2e-37 128.8 0.1 4e-37 127.9 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EQB59840.1 - 6e-06 26.3 0.3 1.1e-05 25.5 0.3 1.4 1 0 0 1 1 1 1 Anticodon binding domain SRP19 PF01922.17 EQB59841.1 - 0.038 14.9 0.1 0.049 14.6 0.1 1.1 1 0 0 1 1 1 0 SRP19 protein SMC_N PF02463.19 EQB59843.1 - 7.6e-27 94.2 8.0 9.3e-27 93.9 8.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EQB59843.1 - 2.6e-21 76.1 0.2 8.2e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EQB59843.1 - 1.2e-09 39.0 21.0 1.2e-09 39.0 21.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 EQB59843.1 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EQB59843.1 - 0.0027 17.5 45.4 0.0064 16.2 45.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EQB59843.1 - 0.0042 16.9 11.1 0.074 12.8 11.1 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EQB59843.1 - 0.096 12.6 0.6 0.42 10.5 0.4 2.1 1 1 1 2 2 2 0 RsgA GTPase SMC_N PF02463.19 EQB59844.1 - 9.4e-22 77.5 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EQB59844.1 - 0.00017 21.6 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MS_channel PF00924.18 EQB59845.1 - 7.6e-16 58.3 4.0 7.6e-16 58.3 4.0 2.6 2 0 0 2 2 2 1 Mechanosensitive ion channel Sigma54_AID PF00309.20 EQB59845.1 - 0.25 11.2 3.8 1.2 9.1 0.4 2.6 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) polyprenyl_synt PF00348.17 EQB59846.1 - 6.9e-30 104.0 0.4 7.9e-30 103.8 0.4 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4413 PF14372.6 EQB59846.1 - 0.027 14.8 0.6 0.027 14.8 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4413) TMEM154 PF15102.6 EQB59847.1 - 0.0016 18.3 0.2 0.0027 17.6 0.2 1.4 1 0 0 1 1 1 1 TMEM154 protein family ABC2_membrane_3 PF12698.7 EQB59847.1 - 0.95 8.5 15.6 0.74 8.9 14.5 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein SAS-6_N PF16531.5 EQB59849.1 - 1.5e-14 54.3 8.0 1.5e-14 54.3 8.0 3.8 2 1 0 2 2 1 1 Centriolar protein SAS N-terminal FPP PF05911.11 EQB59849.1 - 0.00034 19.0 29.5 0.00042 18.7 29.5 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 EQB59849.1 - 0.0015 19.0 41.6 0.083 13.4 24.4 2.8 1 1 2 3 3 3 1 Apg6 coiled-coil region ATG16 PF08614.11 EQB59849.1 - 0.0038 17.5 36.2 0.25 11.6 22.3 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ADIP PF11559.8 EQB59849.1 - 0.0049 17.0 12.3 0.0049 17.0 12.3 3.2 1 1 3 4 4 4 2 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 EQB59849.1 - 0.0052 16.9 45.1 0.067 13.3 7.1 2.3 1 1 1 2 2 2 2 Tropomyosin like Rootletin PF15035.6 EQB59849.1 - 0.014 15.5 41.1 0.084 12.9 10.2 3.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Tropomyosin PF00261.20 EQB59849.1 - 0.02 14.3 38.3 0.025 13.9 25.1 2.1 1 1 1 2 2 2 0 Tropomyosin MAD PF05557.13 EQB59849.1 - 0.022 13.2 37.2 0.031 12.6 37.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 EQB59849.1 - 0.074 11.9 42.3 0.12 11.3 22.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 EQB59849.1 - 0.076 13.7 46.1 0.12 13.1 11.4 3.7 1 1 2 3 3 3 0 Initiation control protein YabA DUF3450 PF11932.8 EQB59849.1 - 0.13 11.6 25.3 0.075 12.3 5.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EQB59849.1 - 0.5 10.4 18.8 1.9 8.5 2.7 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 EQB59849.1 - 0.76 8.6 41.5 2.8 6.7 41.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF724 PF05266.14 EQB59849.1 - 1.4 8.7 36.7 3.7 7.3 11.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Atg14 PF10186.9 EQB59849.1 - 2 7.4 35.1 0.1 11.7 25.3 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EQB59849.1 - 2.6 8.1 37.7 1.7 8.7 22.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 EQB59849.1 - 2.6 7.2 42.6 9.2 5.4 24.2 3.0 1 1 2 3 3 3 0 HAP1 N-terminal conserved region TolA_bind_tri PF16331.5 EQB59849.1 - 3.6 7.7 12.5 1.3 9.1 1.9 3.0 1 1 0 2 2 2 0 TolA binding protein trimerisation UPF0242 PF06785.11 EQB59849.1 - 3.9 7.5 47.0 2.4 8.2 12.0 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus KASH_CCD PF14662.6 EQB59849.1 - 4.1 7.2 49.8 8.6 6.1 22.1 2.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 EQB59849.1 - 4.7 7.2 45.8 9.9 6.2 20.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 EQB59849.1 - 7.2 6.7 37.5 1.9 8.6 12.0 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CLZ PF16526.5 EQB59849.1 - 7.4 7.0 25.7 7.4 7.0 3.2 3.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 EQB59849.1 - 7.6 6.2 14.6 1.9 8.1 11.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF3797 PF12677.7 EQB59850.1 - 0.025 14.4 1.9 0.025 14.4 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) RVT_1 PF00078.27 EQB59851.1 - 1e-34 120.0 0.0 2.1e-34 119.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EQB59851.1 - 0.0014 19.3 0.1 0.0048 17.6 0.1 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase LRR_8 PF13855.6 EQB59852.1 - 1e-15 57.2 18.0 2.9e-09 36.6 5.3 4.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EQB59852.1 - 2.4e-11 43.7 33.0 2.2e-06 27.9 4.2 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB59852.1 - 0.18 11.3 19.9 0.022 14.3 6.3 3.1 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 EQB59852.1 - 1 9.6 15.5 2 8.7 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EQB59852.1 - 1 10.2 33.6 5.5 7.9 0.3 7.6 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_2 PF07723.13 EQB59852.1 - 9.1 7.1 8.1 1.2e+02 3.6 0.1 4.8 4 1 1 5 5 5 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 EQB59857.1 - 2.8e-17 62.6 1.5 4.9e-09 36.2 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EQB59857.1 - 1.1e-15 57.6 5.0 9.5e-08 32.2 0.3 2.3 2 1 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EQB59857.1 - 0.0015 18.5 1.3 0.14 12.2 0.1 2.1 2 0 0 2 2 2 2 SLIDE HSR PF03172.13 EQB59857.1 - 0.04 14.1 1.4 0.15 12.2 0.4 1.9 1 1 1 2 2 2 0 HSR domain DUF4132 PF13569.6 EQB59857.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4132) DUF722 PF05263.11 EQB59857.1 - 0.073 13.3 0.8 0.073 13.3 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF722) SANT_DAMP1_like PF16282.5 EQB59857.1 - 0.11 12.7 3.5 0.2 11.8 1.8 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 GIT_SHD PF08518.11 EQB59858.1 - 4.8e-07 29.3 0.1 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Lambda_Kil PF06301.11 EQB59858.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Bacteriophage lambda Kil protein GrpE PF01025.19 EQB59858.1 - 0.017 14.8 2.6 0.025 14.2 2.2 1.6 1 1 0 1 1 1 0 GrpE AAA PF00004.29 EQB59859.1 - 2.6e-18 66.7 0.0 7e-18 65.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EQB59859.1 - 1.6e-15 57.3 1.9 2.9e-12 46.7 0.1 2.9 2 1 1 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EQB59859.1 - 4e-09 36.6 0.5 1.1e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain Rep_fac_C PF08542.11 EQB59859.1 - 1.2e-08 35.2 0.6 4.7e-08 33.3 0.6 2.0 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.12 EQB59859.1 - 2.8e-07 30.4 0.0 8.8e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EQB59859.1 - 5.5e-07 29.9 0.7 0.0069 16.7 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.6 EQB59859.1 - 7e-06 26.1 2.3 9.4e-06 25.7 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EQB59859.1 - 5.5e-05 23.2 0.2 0.0009 19.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EQB59859.1 - 7.1e-05 22.3 0.0 0.0018 17.7 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EQB59859.1 - 8.3e-05 23.0 0.0 0.0022 18.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EQB59859.1 - 0.00012 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EQB59859.1 - 0.0003 21.1 0.0 0.001 19.4 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 EQB59859.1 - 0.00072 19.4 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EQB59859.1 - 0.0042 16.3 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 EQB59859.1 - 0.0043 17.4 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 EQB59859.1 - 0.0047 16.7 0.0 0.0071 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 EQB59859.1 - 0.0056 15.8 0.0 0.016 14.3 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain AAA_30 PF13604.6 EQB59859.1 - 0.0063 16.2 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EQB59859.1 - 0.0065 16.0 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EQB59859.1 - 0.0069 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EQB59859.1 - 0.0074 16.6 0.8 0.047 14.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 EQB59859.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EQB59859.1 - 0.0083 16.7 0.1 0.034 14.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 EQB59859.1 - 0.011 15.5 0.6 0.36 10.6 0.1 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase TsaE PF02367.17 EQB59859.1 - 0.022 14.8 0.0 0.17 11.9 0.0 2.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EQB59859.1 - 0.023 14.6 0.3 0.95 9.3 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.6 EQB59859.1 - 0.024 14.9 0.1 0.049 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EQB59859.1 - 0.028 13.8 0.1 0.23 10.8 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EQB59859.1 - 0.03 14.1 0.3 0.26 11.0 0.3 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EQB59859.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EQB59859.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_6 PF12774.7 EQB59859.1 - 0.17 10.9 0.0 0.17 10.9 0.0 2.2 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 EQB59859.1 - 0.25 10.9 0.0 4.7 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2_jaz PF12171.8 EQB59860.1 - 2.6e-10 40.3 3.8 2.6e-10 40.3 3.8 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EQB59860.1 - 0.00011 22.4 0.8 0.00023 21.4 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EQB59860.1 - 0.056 14.3 0.3 0.14 13.1 0.2 1.8 1 1 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.12 EQB59860.1 - 0.073 12.9 0.8 0.073 12.9 0.8 2.2 3 0 0 3 3 3 0 U1 zinc finger DUF3973 PF13119.6 EQB59860.1 - 1.8 8.7 5.8 10 6.3 4.8 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3973) CDC37_N PF03234.14 EQB59860.1 - 5.5 7.9 8.8 19 6.2 8.8 1.8 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DnaJ PF00226.31 EQB59861.1 - 6.6e-14 51.8 1.7 1.2e-13 51.0 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain SHOCT PF09851.9 EQB59862.1 - 0.042 13.6 0.5 0.73 9.6 0.3 2.6 2 0 0 2 2 2 0 Short C-terminal domain Sec20 PF03908.13 EQB59863.1 - 0.00086 19.2 0.9 0.00086 19.2 0.9 1.8 2 0 0 2 2 2 1 Sec20 GCR1_C PF12550.8 EQB59863.1 - 0.0017 18.6 0.9 0.0017 18.6 0.9 1.8 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF2294 PF10057.9 EQB59863.1 - 0.0092 16.1 1.0 0.019 15.1 1.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) CsgE PF10627.9 EQB59863.1 - 0.04 14.1 0.2 0.072 13.3 0.2 1.6 1 1 0 1 1 1 0 Curli assembly protein CsgE DUF2721 PF11026.8 EQB59863.1 - 0.15 12.0 0.2 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) GATA PF00320.27 EQB59864.1 - 2.2e-16 59.1 6.9 2.2e-16 59.1 6.9 3.1 3 0 0 3 3 3 1 GATA zinc finger FYVE PF01363.21 EQB59864.1 - 0.11 12.6 2.8 6 7.1 0.1 2.5 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 EQB59864.1 - 0.17 11.9 7.6 40 4.3 8.1 3.1 1 1 1 2 2 2 0 Double zinc ribbon ADK_lid PF05191.14 EQB59864.1 - 6.7 6.8 7.3 15 5.7 1.2 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-C4_ClpX PF06689.13 EQB59864.1 - 9 6.3 7.2 0.7 9.8 0.4 2.4 3 0 0 3 3 3 0 ClpX C4-type zinc finger RRM_1 PF00076.22 EQB59865.1 - 3.2e-29 100.5 7.9 9.6e-11 41.4 0.2 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 EQB59865.1 - 2.3e-08 34.0 0.9 0.017 15.2 0.0 3.1 1 1 2 3 3 3 2 RNA binding domain DUF1866 PF08952.11 EQB59865.1 - 8.8e-08 32.1 0.2 0.054 13.3 0.0 3.2 1 1 2 3 3 3 3 Domain of unknown function (DUF1866) RRM_3 PF08777.11 EQB59865.1 - 6e-06 26.2 2.4 0.3 11.2 0.1 3.2 2 1 1 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 EQB59865.1 - 6.8e-06 26.0 2.2 0.098 12.7 0.1 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EQB59865.1 - 1e-05 25.6 1.3 1.1 9.4 0.0 4.4 2 2 2 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 EQB59865.1 - 1.2e-05 24.9 6.0 0.054 13.1 0.2 3.1 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EQB59865.1 - 0.00059 20.0 1.2 5.5 7.3 0.0 3.8 3 2 0 3 3 3 1 BRCA1-associated protein 2 SET_assoc PF11767.8 EQB59865.1 - 0.016 14.9 0.2 1 9.1 0.1 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Nup35_RRM PF05172.13 EQB59865.1 - 0.057 13.4 9.9 2.1 8.4 0.6 3.6 1 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 EQB59865.1 - 0.063 13.2 5.7 1.1 9.2 0.1 3.4 3 1 0 3 3 3 0 RL domain RRM_Rrp7 PF17799.1 EQB59865.1 - 0.13 12.1 6.7 0.52 10.1 0.1 3.2 1 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain WD40 PF00400.32 EQB59866.1 - 4.2e-19 68.5 0.6 5e-07 30.3 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Sof1 PF04158.14 EQB59866.1 - 1.3e-15 57.4 6.3 1.3e-15 57.4 6.3 2.3 2 0 0 2 2 2 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EQB59866.1 - 8.9e-09 35.5 0.1 0.00096 19.4 0.0 3.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EQB59866.1 - 0.0028 17.6 0.1 0.094 12.6 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 EQB59866.1 - 0.019 15.0 0.0 0.53 10.3 0.0 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region SBBP PF06739.11 EQB59866.1 - 1.9 8.6 4.0 0.44 10.6 0.2 1.9 2 0 0 2 2 2 0 Beta-propeller repeat NUDIX PF00293.28 EQB59867.1 - 9.6e-06 25.7 0.2 0.00061 19.8 0.2 2.8 1 1 0 1 1 1 1 NUDIX domain DUF4638 PF15472.6 EQB59869.1 - 0.0091 15.8 2.6 0.011 15.5 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4638) Calcipressin PF04847.12 EQB59869.1 - 0.073 12.8 0.6 0.091 12.5 0.6 1.3 1 1 0 1 1 1 0 Calcipressin MIS13 PF08202.11 EQB59869.1 - 0.22 10.8 12.1 0.28 10.4 12.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Nnf1 PF03980.14 EQB59869.1 - 3.1 8.2 10.3 10 6.5 10.2 2.1 1 1 0 1 1 1 0 Nnf1 LNS2 PF08235.13 EQB59870.1 - 9.1e-89 296.8 0.0 1.9e-88 295.8 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EQB59870.1 - 2.2e-22 78.9 0.3 5.6e-22 77.6 0.3 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region DUF4479 PF14794.6 EQB59870.1 - 0.00067 19.5 0.2 0.0022 17.8 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4479) MICSWaP PF17018.5 EQB59872.1 - 8.9e-50 168.9 1.1 1.1e-49 168.7 1.1 1.0 1 0 0 1 1 1 1 Spore wall protein HydF_tetramer PF18133.1 EQB59872.1 - 0.092 12.5 0.1 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Hydrogen maturase F tetramerization domain RicinB_lectin_2 PF14200.6 EQB59873.1 - 0.006 17.3 0.1 0.019 15.7 0.1 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ran_BP1 PF00638.18 EQB59874.1 - 1.8e-19 70.2 1.0 1.8e-19 70.2 1.0 1.8 2 1 1 3 3 3 1 RanBP1 domain BssS PF13991.6 EQB59875.1 - 0.084 12.9 0.2 0.81 9.8 0.0 2.2 2 1 0 2 2 2 0 BssS protein family WG_beta_rep PF14903.6 EQB59877.1 - 0.054 13.8 0.1 0.054 13.8 0.1 2.9 3 1 0 3 3 3 0 WG containing repeat HSP70 PF00012.20 EQB59878.1 - 1e-93 314.6 2.2 1.6e-93 314.0 2.2 1.2 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EQB59878.1 - 1.7e-05 23.8 0.0 0.00039 19.3 0.0 2.9 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 EQB59878.1 - 0.05 14.0 0.5 26 5.3 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA RVT_1 PF00078.27 EQB59880.1 - 2.2e-24 86.2 0.3 2.9e-24 85.8 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glutaredoxin PF00462.24 EQB59881.1 - 5.1e-07 29.8 0.0 1.8e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin ORC5_C PF14630.6 EQB59881.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.2 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Glutaredoxin PF00462.24 EQB59882.1 - 0.00016 21.8 0.0 0.00061 20.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin DUF3369 PF11849.8 EQB59882.1 - 0.038 14.2 0.5 0.089 13.0 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3369) SlyX PF04102.12 EQB59883.1 - 1 10.1 4.3 16 6.2 0.2 3.6 1 1 3 4 4 4 0 SlyX IncF PF17626.2 EQB59885.1 - 0.064 13.6 1.5 11 6.5 0.1 2.1 2 0 0 2 2 2 0 Inclusion membrane protein F HAMP_N3 PF18575.1 EQB59885.1 - 0.12 11.9 0.0 16 5.2 0.0 2.2 2 0 0 2 2 2 0 HAMP N-terminal domain 3 EGF PF00008.27 EQB59885.1 - 0.44 10.9 10.9 3.2 8.1 1.1 2.4 2 0 0 2 2 2 0 EGF-like domain PseudoU_synth_1 PF01416.20 EQB59888.1 - 0.086 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridine synthase Tai4 PF16695.5 EQB59889.1 - 0.015 15.8 1.5 0.072 13.6 0.4 2.3 1 1 1 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein vATP-synt_AC39 PF01992.16 EQB59890.1 - 1.2e-07 31.6 5.6 4.1e-06 26.5 0.5 2.0 2 0 0 2 2 2 2 ATP synthase (C/AC39) subunit Spot_14 PF07084.12 EQB59891.1 - 0.0055 16.8 0.0 0.0058 16.8 0.0 1.1 1 0 0 1 1 1 1 Thyroid hormone-inducible hepatic protein Spot 14 Staphylokinase PF02821.16 EQB59891.1 - 0.039 14.4 0.3 0.053 14.0 0.2 1.3 1 1 0 1 1 1 0 Staphylokinase/Streptokinase family Beta_lactamase3 PF17030.5 EQB59892.1 - 7.3e-22 77.7 6.9 1.9e-12 46.9 0.1 3.5 2 1 0 3 3 3 2 Putative beta-lactamase-like family Lactamase_B_6 PF16661.5 EQB59892.1 - 0.025 14.0 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain DNA_ligase_A_M PF01068.21 EQB59894.1 - 7.2e-57 192.3 1.8 1.2e-56 191.6 1.8 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EQB59894.1 - 1.3e-26 93.9 0.3 8e-26 91.4 1.2 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EQB59894.1 - 1.6e-22 80.0 0.0 3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EQB59894.1 - 1.3e-05 25.6 0.9 2.2e-05 24.8 0.9 1.4 1 0 0 1 1 1 1 RNA ligase DUF1474 PF07342.11 EQB59894.1 - 0.023 15.2 0.3 0.079 13.5 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1474) mRNA_cap_enzyme PF01331.19 EQB59894.1 - 0.065 13.0 2.9 1.4 8.7 2.9 2.5 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain tRNA-synt_1c PF00749.21 EQB59895.1 - 4.5e-84 282.0 1.2 7.5e-84 281.3 1.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EQB59895.1 - 8.8e-11 42.0 0.9 3.3e-10 40.1 0.6 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain TAFII28 PF04719.14 EQB59896.1 - 1.9e-33 114.4 0.0 2.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region SpvD PF05563.12 EQB59896.1 - 0.033 13.8 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD RAG1 PF12940.7 EQB59896.1 - 0.065 11.3 0.0 0.071 11.2 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase DUF5065 PF16723.5 EQB59896.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) Cnd1 PF12717.7 EQB59897.1 - 1.1e-08 35.4 5.0 1.1e-08 35.4 5.0 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EQB59897.1 - 0.00088 19.3 0.0 0.9 10.0 0.0 2.9 2 0 0 2 2 2 2 HEAT repeat DUF4878 PF12870.7 EQB59897.1 - 1.9 8.8 6.2 0.22 11.8 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Homeodomain PF00046.29 EQB59899.1 - 1.2e-10 41.1 0.5 1.9e-10 40.4 0.5 1.2 1 0 0 1 1 1 1 Homeodomain IFT46_B_C PF12317.8 EQB59899.1 - 0.00023 20.9 0.2 0.0003 20.6 0.2 1.3 1 1 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Zip PF02535.22 EQB59900.1 - 4.7 6.3 5.4 4.6 6.4 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PIN_2 PF10130.9 EQB59901.1 - 0.059 13.6 1.3 0.091 13.0 1.1 1.5 1 1 0 1 1 1 0 PIN domain SNARE PF05739.19 EQB59901.1 - 0.23 11.5 6.3 2.5 8.2 6.3 2.2 1 1 0 1 1 1 0 SNARE domain AlkA_N PF06029.11 EQB59902.1 - 0.19 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 AlkA N-terminal domain MCM PF00493.23 EQB59903.1 - 2.1e-100 334.4 0.0 3.4e-100 333.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EQB59903.1 - 5.7e-33 113.5 0.2 1.1e-32 112.6 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EQB59903.1 - 1.3e-27 96.0 1.1 3e-27 94.8 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 EQB59903.1 - 5.7e-07 29.6 0.0 1.9e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EQB59903.1 - 8.4e-07 28.6 0.1 2.2e-05 24.0 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EQB59903.1 - 0.00026 20.9 0.0 0.00061 19.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.6 EQB59903.1 - 0.0013 19.3 1.4 0.0013 19.3 1.4 2.8 2 0 0 2 2 2 1 MCM N-terminal domain SusD-like_3 PF14322.6 EQB59903.1 - 0.077 13.3 1.4 0.2 12.0 1.4 1.7 1 0 0 1 1 1 0 Starch-binding associating with outer membrane PI3_PI4_kinase PF00454.27 EQB59907.1 - 2.8e-07 30.6 1.1 0.00042 20.2 0.6 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase TMF_DNA_bd PF12329.8 EQB59907.1 - 0.019 15.0 2.1 0.045 13.7 2.1 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Peptidase_M19 PF01244.21 EQB59915.1 - 0.051 12.7 0.2 0.085 12.0 0.2 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) RRXRR PF14239.6 EQB59916.1 - 0.068 13.0 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 RRXRR protein DUF2439 PF10382.9 EQB59918.1 - 1e-06 29.0 3.2 1e-06 29.0 3.2 3.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2439) Phage_head_chap PF11113.8 EQB59918.1 - 0.042 14.0 0.6 0.11 12.6 0.6 1.7 1 0 0 1 1 1 0 Head assembly gene product NFACT-R_1 PF05670.13 EQB59919.1 - 1.8e-05 25.3 0.1 3e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain RVT_1 PF00078.27 EQB59920.1 - 1.7e-12 47.3 0.6 2.7e-12 46.7 0.6 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) vATP-synt_E PF01991.18 EQB59920.1 - 0.0095 15.4 0.4 0.015 14.7 0.4 1.2 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit AgrD PF05931.11 EQB59920.1 - 0.51 10.4 3.2 0.56 10.3 1.1 2.2 2 0 0 2 2 2 0 Staphylococcal AgrD protein Arabino_trans_C PF14896.6 EQB59922.1 - 5.2 6.0 10.1 9.5 5.1 10.1 1.4 1 0 0 1 1 1 0 EmbC C-terminal domain Toprim PF01751.22 EQB59923.1 - 1.3e-10 41.5 1.8 1.7e-10 41.0 0.3 1.9 2 0 0 2 2 2 1 Toprim domain NAD_binding_7 PF13241.6 EQB59923.1 - 1.1 9.7 4.5 0.41 11.1 0.2 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding RNase_HII PF01351.18 EQB59924.1 - 5.5e-25 88.4 0.1 2.4e-17 63.5 0.0 2.4 2 1 0 2 2 2 2 Ribonuclease HII Toprim_2 PF13155.6 EQB59925.1 - 0.063 13.7 0.1 0.19 12.2 0.1 1.8 1 0 0 1 1 1 0 Toprim-like RVT_1 PF00078.27 EQB59926.1 - 1.1e-28 100.3 3.2 1.3e-28 100.0 0.4 2.3 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EQB59926.1 - 6.3e-24 83.9 0.1 1.5e-23 82.7 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EQB59926.1 - 1e-16 61.1 0.0 2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 EQB59926.1 - 7.6e-05 22.6 6.4 0.00018 21.4 6.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EQB59926.1 - 0.079 12.7 3.3 0.16 11.7 3.3 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EQB59926.1 - 6.7 6.6 6.7 2.3 8.1 3.0 2.1 2 0 0 2 2 2 0 Zinc knuckle DUF2028 PF09667.10 EQB59927.1 - 0.0014 18.6 2.2 0.0024 17.8 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2028) Com_YlbF PF06133.11 EQB59927.1 - 0.022 15.4 6.2 0.049 14.2 1.7 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA CPG4 PF15481.6 EQB59927.1 - 0.53 10.9 4.2 13 6.5 0.2 2.4 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 RIO1 PF01163.22 EQB59928.1 - 6.9e-50 169.3 1.7 9.5e-50 168.8 1.7 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EQB59928.1 - 0.017 13.9 0.1 0.021 13.6 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_8 PF13855.6 EQB59929.1 - 1.5e-09 37.4 15.2 3.6e-06 26.7 3.0 3.6 2 2 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EQB59929.1 - 1e-05 25.8 21.3 0.00048 20.5 1.7 4.8 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) DASH_Dam1 PF08653.10 EQB59929.1 - 0.0003 20.5 0.3 0.017 14.9 0.1 3.0 3 0 0 3 3 3 1 DASH complex subunit Dam1 LRR_5 PF13306.6 EQB59929.1 - 0.07 13.1 3.1 0.27 11.2 2.8 2.0 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EQB59929.1 - 0.76 10.6 18.9 2.7 8.9 0.1 5.6 4 3 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 EQB59930.1 - 4.4e-07 29.6 5.0 1.6e-06 27.8 2.0 3.0 1 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EQB59930.1 - 4.4e-05 23.7 15.2 0.00057 20.2 6.9 3.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB59930.1 - 0.0014 18.1 3.9 0.0028 17.2 3.6 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Recep_L_domain PF01030.24 EQB59930.1 - 1.1 9.4 11.9 3.1 8.0 8.8 2.3 1 1 1 2 2 2 0 Receptor L domain VATC PF18716.1 EQB59932.1 - 0.023 14.5 0.7 0.052 13.4 0.7 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain Vasculin PF15337.6 EQB59933.1 - 0.19 12.6 0.1 0.19 12.6 0.1 2.6 1 1 2 3 3 3 0 Vascular protein family Vasculin-like 1 Bromodomain PF00439.25 EQB59934.1 - 0.019 15.0 1.0 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Bromodomain DnaB_2 PF07261.11 EQB59934.1 - 0.054 13.2 0.7 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 Replication initiation and membrane attachment Sel1 PF08238.12 EQB59936.1 - 1.8e-10 41.2 7.4 0.00017 22.2 0.0 4.6 4 0 0 4 4 4 3 Sel1 repeat Sdh5 PF03937.16 EQB59936.1 - 0.23 11.4 2.6 0.29 11.1 0.2 2.2 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase tRNA-synt_1b PF00579.25 EQB59938.1 - 5.6e-39 134.2 0.0 6.5e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_M26_C PF07580.14 EQB59938.1 - 0.0022 16.6 0.6 0.0055 15.3 0.5 1.6 1 1 1 2 2 2 1 M26 IgA1-specific Metallo-endopeptidase C-terminal region Parvo_NS1 PF01057.17 EQB59938.1 - 0.021 13.9 0.0 0.025 13.7 0.0 1.4 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 Flavodoxin_1 PF00258.25 EQB59939.1 - 2.2e-17 63.6 0.0 6.7e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin SPAM PF02090.15 EQB59940.1 - 1.2 8.9 8.5 0.66 9.8 0.6 2.3 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein Colicin-DNase PF12639.7 EQB59940.1 - 3.3 8.6 9.8 0.23 12.3 2.1 2.5 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin APC_u14 PF16635.5 EQB59940.1 - 7.1 7.2 10.3 7.4 7.2 0.6 2.4 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr DUF5101 PF17031.5 EQB59941.1 - 1.7e-27 95.4 13.7 1.9e-27 95.3 13.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5101) HMMR_N PF15905.5 EQB59941.1 - 0.033 13.7 10.5 0.038 13.4 10.5 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal NRBF2 PF08961.10 EQB59941.1 - 0.064 12.9 5.5 0.042 13.5 3.4 1.5 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2312 PF10073.9 EQB59941.1 - 0.25 11.0 6.4 2 8.1 6.1 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) TSC22 PF01166.18 EQB59941.1 - 2.6 8.4 9.4 0.59 10.5 5.1 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 EQB59941.1 - 5 7.8 10.6 0.66 10.6 3.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA LMBR1 PF04791.16 EQB59941.1 - 5 5.9 5.1 5 5.9 5.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein PCYCGC PF13798.6 EQB59943.1 - 0.036 13.9 1.2 0.069 13.0 0.1 1.9 1 1 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF4250 PF14056.6 EQB59943.1 - 0.059 13.3 0.4 0.059 13.3 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) HIP1_clath_bdg PF16515.5 EQB59943.1 - 0.54 10.9 12.0 0.15 12.7 1.9 2.4 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RRM_1 PF00076.22 EQB59945.1 - 0.0007 19.4 0.1 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EMP24_GP25L PF01105.24 EQB59946.1 - 2.5e-05 24.3 0.3 2.7e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glyco_transf_20 PF00982.21 EQB59947.1 - 1.9e-118 396.1 5.8 3.6e-79 266.6 4.9 2.3 1 1 1 2 2 2 2 Glycosyltransferase family 20 zf-CCCH PF00642.24 EQB59948.1 - 2.5e-20 71.8 16.0 1.2e-11 44.2 3.5 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EQB59948.1 - 1.6e-08 34.3 15.3 0.00034 20.6 6.4 2.8 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EQB59948.1 - 4.4e-07 29.6 12.0 0.0019 18.0 2.0 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Defensin_int PF17858.1 EQB59948.1 - 0.11 12.5 0.2 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Platypus intermediate defensin-like peptide Torus PF16131.5 EQB59948.1 - 0.42 11.3 15.9 0.2 12.4 1.8 2.8 2 1 1 3 3 3 0 Torus domain CLIP_SPH_mas PF18398.1 EQB59948.1 - 7.3 7.1 12.4 2 8.9 1.8 3.5 3 0 0 3 3 3 0 Clip-domain serine protease homolog masquerade zf-C3HC4_3 PF13920.6 EQB59950.1 - 2.5e-06 27.2 11.5 2.5e-06 27.2 11.5 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EQB59950.1 - 0.00015 22.0 10.7 0.00015 22.0 10.7 4.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB59950.1 - 0.00069 19.4 11.9 0.00069 19.4 11.9 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EQB59950.1 - 0.0015 18.4 12.8 0.0015 18.4 12.8 4.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 EQB59950.1 - 0.0061 16.9 2.2 0.0061 16.9 2.2 4.5 5 0 0 5 5 5 1 Zinc-finger of C2H2 type Prok-RING_4 PF14447.6 EQB59950.1 - 0.0062 16.4 9.3 0.0062 16.4 9.3 4.3 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EQB59950.1 - 0.019 15.0 11.7 0.019 15.0 11.7 4.9 5 1 0 5 5 5 0 zinc-RING finger domain DUF1062 PF06353.12 EQB59950.1 - 1.1 10.1 10.2 0.1 13.5 3.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1062) MSA-2c PF12238.8 EQB59950.1 - 2.2 8.2 9.5 0.34 10.9 3.9 2.3 1 1 0 2 2 2 0 Merozoite surface antigen 2c Myb_DNA-binding PF00249.31 EQB59951.1 - 2.9e-09 37.0 0.2 5.1e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EQB59951.1 - 1.3e-05 25.3 0.2 3.5e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 EQB59951.1 - 0.0002 21.4 0.7 0.00043 20.3 0.7 1.5 1 0 0 1 1 1 1 SLIDE PGM_PMM_I PF02878.16 EQB59952.1 - 8.5e-15 54.7 0.0 2.8e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EQB59952.1 - 1.7e-07 31.3 0.0 4.5e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EQB59952.1 - 6.8e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EQB59952.1 - 9.8e-05 22.9 1.1 0.0013 19.4 0.1 3.1 4 0 0 4 4 4 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF5098 PF17023.5 EQB59953.1 - 1.7e-34 119.6 28.8 2e-34 119.3 28.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) DUF4634 PF15465.6 EQB59953.1 - 0.026 14.8 1.6 0.063 13.6 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) T2SS_PulS_OutS PF09691.10 EQB59953.1 - 0.042 14.0 0.6 0.12 12.5 0.6 1.8 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) Phage_int_SAM_2 PF12834.7 EQB59953.1 - 0.054 14.2 2.0 0.099 13.3 0.2 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal DUF5497 PF17601.2 EQB59953.1 - 3.1 8.2 11.1 0.16 12.3 1.7 3.0 2 2 1 3 3 3 0 Family of unknown function (DUF5497) DUF5098 PF17023.5 EQB59954.1 - 8.2e-35 120.7 24.5 1e-34 120.4 24.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5098) Phage_int_SAM_2 PF12834.7 EQB59954.1 - 0.026 15.2 0.2 0.081 13.6 0.2 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal Pkinase PF00069.25 EQB59955.1 - 7.5e-73 245.1 0.4 7.5e-73 245.1 0.4 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB59955.1 - 1.6e-41 142.3 0.0 2.4e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EQB59955.1 - 1.6e-11 44.2 0.4 2.5e-07 30.8 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EQB59955.1 - 1e-05 25.0 0.0 4.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EQB59955.1 - 7.8e-05 21.8 0.4 0.00016 20.8 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EQB59955.1 - 0.0012 17.7 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EQB59955.1 - 0.049 13.2 2.4 1.4 8.5 0.4 2.4 1 1 1 2 2 2 0 RIO1 family CTD_bind PF04818.13 EQB59956.1 - 6.2e-08 33.4 2.4 1.2e-07 32.5 2.4 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RNA_pol_L PF01193.24 EQB59957.1 - 1.2e-17 63.0 0.0 1.6e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 EQB59957.1 - 1.3e-16 60.9 0.0 7.5e-15 55.3 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain PhoU_div PF01865.16 EQB59959.1 - 0.0074 15.6 0.3 0.01 15.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF47 FOXO_KIX_bdg PF16675.5 EQB59959.1 - 0.09 13.1 0.8 0.16 12.3 0.8 1.3 1 0 0 1 1 1 0 KIX-binding domain of forkhead box O, CR2 TPD52 PF04201.15 EQB59959.1 - 0.12 12.0 1.2 0.16 11.6 1.2 1.2 1 0 0 1 1 1 0 Tumour protein D52 family HMMR_N PF15905.5 EQB59959.1 - 0.45 9.9 7.0 0.59 9.6 7.0 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GTP_EFTU PF00009.27 EQB59960.1 - 3.3e-26 92.0 0.2 1.9e-25 89.5 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.11 EQB59960.1 - 5.4e-26 90.7 0.5 1.6e-25 89.1 0.1 2.1 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 EQB59960.1 - 2.2e-10 40.8 0.1 5.2e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EQB59960.1 - 7.6e-05 22.7 0.3 0.00069 19.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EQB59960.1 - 0.0006 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Tfb2 PF03849.14 EQB59961.1 - 5.8e-10 38.7 0.4 8.4e-10 38.2 0.4 1.3 1 0 0 1 1 1 1 Transcription factor Tfb2 PTP_tm PF18861.1 EQB59961.1 - 9.2 6.2 10.7 0.96 9.4 5.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Sporozoite_P67 PF05642.11 EQB59963.1 - 0.00033 18.9 4.6 0.00036 18.8 4.6 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen MAP17 PF15807.5 EQB59963.1 - 0.01 16.1 0.1 0.023 14.9 0.0 1.6 1 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CobT PF06213.12 EQB59963.1 - 0.031 13.7 0.9 0.035 13.5 0.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Conotoxin PF02950.17 EQB59963.1 - 0.04 14.9 0.0 0.048 14.7 0.0 1.2 1 0 0 1 1 1 0 Conotoxin RNA_pol_Rpc4 PF05132.14 EQB59963.1 - 0.089 13.2 3.1 0.11 12.9 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Orf78 PF06024.12 EQB59963.1 - 0.097 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) PBP1_TM PF14812.6 EQB59963.1 - 0.098 13.0 0.2 0.098 13.0 0.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Polyoma_lg_T_C PF06431.11 EQB59963.1 - 0.17 10.7 0.9 0.18 10.6 0.9 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus PGA2 PF07543.12 EQB59963.1 - 0.27 11.2 3.1 0.33 10.9 3.1 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 EQB59963.1 - 0.5 8.6 3.9 0.57 8.4 3.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Lactamase_B_6 PF16661.5 EQB59964.1 - 3.8e-15 55.8 1.5 2e-12 47.0 1.3 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily domain YcxB PF14317.6 EQB59965.1 - 0.00016 21.3 1.1 0.00032 20.3 1.1 1.6 1 0 0 1 1 1 1 YcxB-like protein DUF1699 PF08004.11 EQB59965.1 - 0.017 14.8 0.8 0.032 13.9 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) DUF4296 PF14129.6 EQB59966.1 - 0.023 15.3 4.2 0.023 15.3 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) STAT_bind PF02864.15 EQB59967.1 - 0.017 15.7 4.5 0.017 15.7 4.5 3.5 2 1 1 3 3 3 0 STAT protein, DNA binding domain GRASP55_65 PF04495.14 EQB59968.1 - 1.1e-17 64.6 0.2 3.1e-15 56.7 0.1 2.3 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EQB59968.1 - 3.1e-05 23.7 0.0 0.0092 15.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EQB59968.1 - 0.00015 22.0 0.0 0.0021 18.4 0.0 2.7 2 0 0 2 2 2 1 PDZ domain DS PF01916.17 EQB59978.1 - 0.33 10.2 3.7 0.2 10.9 1.4 1.8 1 1 1 2 2 2 0 Deoxyhypusine synthase Pneumo_att_G PF05539.11 EQB59981.1 - 0.69 9.4 20.6 0.91 9.1 20.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Nucleoporin_FG PF13634.6 EQB59981.1 - 1.6 9.7 75.2 2.7 8.9 46.1 2.8 1 1 1 2 2 2 0 Nucleoporin FG repeat region TFIIA_gamma_N PF02268.16 EQB59982.1 - 4e-16 58.8 0.0 5.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EQB59982.1 - 2.3e-14 53.3 2.1 4.5e-14 52.3 2.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Ubiquitin_4 PF18036.1 EQB59982.1 - 0.018 15.0 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2680 PF10925.8 EQB59982.1 - 0.049 13.6 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Pkinase PF00069.25 EQB59983.1 - 8.3e-43 146.6 9.6 3.2e-39 134.9 6.3 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EQB59983.1 - 1.4e-28 99.9 1.2 5.8e-27 94.6 0.6 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 EQB59983.1 - 0.0066 16.1 0.5 0.19 11.3 0.2 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EQB59983.1 - 0.0092 14.8 0.6 0.015 14.1 0.6 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EQB59983.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1388 PF07142.12 EQB59983.1 - 1.9 8.5 2.7 1.7 8.7 1.2 1.8 2 1 0 2 2 2 0 Repeat of unknown function (DUF1388) Pkinase PF00069.25 EQB59984.1 - 1.1e-26 93.8 0.7 1.5e-26 93.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB59984.1 - 2.6e-15 56.4 0.0 3.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EQB59984.1 - 0.021 13.6 0.2 0.041 12.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EQB59984.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1388 PF07142.12 EQB59984.1 - 0.65 10.0 2.7 1.2 9.2 1.6 1.9 2 1 0 2 2 2 0 Repeat of unknown function (DUF1388) NifZ PF04319.13 EQB59985.1 - 0.041 13.7 1.2 0.2 11.4 1.1 2.1 1 1 1 2 2 2 0 NifZ domain GSHPx PF00255.19 EQB59986.1 - 1.8e-18 66.1 1.8 2.4e-18 65.7 0.3 1.8 2 0 0 2 2 2 1 Glutathione peroxidase TraF PF13728.6 EQB59987.1 - 0.00033 20.5 0.4 0.0085 15.9 0.1 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein BsuBI_PstI_RE PF06616.11 EQB59987.1 - 0.019 14.2 0.6 0.04 13.2 0.3 1.6 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain zf-RVT PF13966.6 EQB59987.1 - 0.037 14.7 0.3 0.08 13.7 0.3 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glutaredoxin PF00462.24 EQB59987.1 - 0.038 14.2 0.2 0.15 12.3 0.2 2.0 1 0 0 1 1 1 0 Glutaredoxin HSDR_N_2 PF13588.6 EQB59987.1 - 0.056 13.4 2.8 0.1 12.6 1.8 1.9 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Cpn60_TCP1 PF00118.24 EQB59989.1 - 7.1e-39 133.8 3.8 8.2e-39 133.5 3.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WIYLD PF10440.9 EQB59989.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Cpn60_TCP1 PF00118.24 EQB59990.1 - 3.8e-58 197.3 2.0 4.8e-58 197.0 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3921 PF13060.6 EQB59990.1 - 0.01 15.8 0.1 0.036 14.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) RD3 PF14473.6 EQB59990.1 - 0.024 14.5 0.5 0.16 11.8 0.1 2.1 1 1 1 2 2 2 0 RD3 protein DUF4407 PF14362.6 EQB59991.1 - 2.2 7.6 6.4 3.4 6.9 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAR2 PF05282.11 EQB59992.1 - 0.13 11.6 2.1 0.17 11.3 2.1 1.2 1 0 0 1 1 1 0 AAR2 protein Pkinase PF00069.25 EQB59993.1 - 2.6e-10 40.1 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB59993.1 - 7.3e-09 35.3 0.0 8.5e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase YdjO PF14169.6 EQB59993.1 - 0.054 13.2 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Cold-inducible protein YdjO Kinase-like PF14531.6 EQB59993.1 - 0.055 12.8 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DBD_Tnp_Mut PF03108.15 EQB59993.1 - 0.062 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 MuDR family transposase FTO_CTD PF12934.7 EQB59994.1 - 0.092 12.5 1.8 1.5 8.5 0.1 2.2 1 1 1 2 2 2 0 FTO C-terminal domain KNOX2 PF03791.13 EQB59994.1 - 0.11 12.1 0.1 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 KNOX2 domain CIAPIN1 PF05093.13 EQB59995.1 - 1.3e-11 44.9 13.7 9.3e-11 42.1 1.7 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF2981 PF11200.8 EQB59997.1 - 0.83 9.3 6.6 0.97 9.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Mago_nashi PF02792.14 EQB59997.1 - 6.7 6.8 8.9 0.99 9.5 2.9 2.1 1 1 1 2 2 2 0 Mago nashi protein PC_rep PF01851.22 EQB59999.1 - 0.00083 19.7 11.1 1.5 9.4 0.7 4.6 5 0 0 5 5 5 3 Proteasome/cyclosome repeat Peroxidase_2 PF01328.17 EQB60000.1 - 0.29 11.6 2.5 2.9 8.4 2.4 2.4 1 1 0 1 1 1 0 Peroxidase, family 2 RL10P_insert PF17777.1 EQB60000.1 - 0.36 10.8 1.8 34 4.5 0.1 3.4 2 1 2 4 4 4 0 Insertion domain in 60S ribosomal protein L10P Peptidase_M48 PF01435.18 EQB60004.1 - 6.5e-08 32.6 0.0 8.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 EF1G PF00647.19 EQB60004.1 - 0.0029 17.7 2.9 0.0029 17.7 2.9 1.8 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain Ras_bdg_2 PF14847.6 EQB60004.1 - 0.0065 16.8 0.8 0.013 15.8 0.8 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Nucleoporin2 PF04096.14 EQB60006.1 - 1.7e-13 50.9 0.1 3.4e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase TFIIA_gamma_N PF02268.16 EQB60007.1 - 4e-16 58.8 0.0 5.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EQB60007.1 - 2.3e-14 53.3 2.1 4.5e-14 52.3 2.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Ubiquitin_4 PF18036.1 EQB60007.1 - 0.018 15.0 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2680 PF10925.8 EQB60007.1 - 0.049 13.6 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Pkinase PF00069.25 EQB60008.1 - 8.2e-34 117.2 1.7 4e-26 92.0 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60008.1 - 3.9e-15 55.8 0.2 8e-15 54.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EQB60008.1 - 0.053 12.3 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EQB60008.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4661 PF15576.6 EQB60012.1 - 5.5 6.8 4.8 6.5 6.6 4.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) Adap_comp_sub PF00928.21 EQB60013.1 - 7.8e-08 32.0 7.5 1.3e-07 31.3 7.5 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF2373 PF10180.9 EQB60013.1 - 0.013 15.4 0.0 0.055 13.3 0.0 2.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DEK_C PF08766.11 EQB60014.1 - 0.008 16.1 3.1 1.4 8.9 0.8 2.6 1 1 1 2 2 2 2 DEK C terminal domain TAP_C PF03943.13 EQB60015.1 - 0.12 12.0 0.2 0.28 10.8 0.2 1.6 1 0 0 1 1 1 0 TAP C-terminal domain HSDR_N_2 PF13588.6 EQB60016.1 - 0.00046 20.1 1.3 0.00085 19.3 1.3 1.5 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) MTES_1575 PF18741.1 EQB60016.1 - 0.0095 16.1 2.0 0.014 15.5 1.0 1.7 1 1 1 2 2 2 1 REase_MTES_1575 DUF4263 PF14082.6 EQB60016.1 - 0.15 12.3 4.6 0.42 10.9 3.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4263) RT_RNaseH PF17917.1 EQB60017.1 - 2.2e-15 56.8 0.1 7.8e-15 55.1 0.1 2.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EQB60017.1 - 1.7e-09 37.9 0.0 4.5e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EQB60017.1 - 5e-07 29.7 1.4 1.9e-06 27.9 1.4 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 EQB60017.1 - 8e-06 25.8 0.1 3.3e-05 23.9 0.1 2.1 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 EQB60017.1 - 2.6e-05 24.3 1.0 2.6e-05 24.3 1.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger rve_3 PF13683.6 EQB60017.1 - 0.015 15.0 0.1 0.046 13.5 0.1 1.8 1 0 0 1 1 1 0 Integrase core domain EST1 PF10374.9 EQB60017.1 - 0.071 13.7 0.9 0.28 11.8 0.1 2.6 2 0 0 2 2 2 0 Telomerase activating protein Est1 DUF3850 PF12961.7 EQB60017.1 - 1.1 9.3 5.5 0.72 9.9 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3850) LRR_2 PF07723.13 EQB60018.1 - 0.42 11.4 3.1 18 6.2 0.0 3.5 3 1 1 4 4 4 0 Leucine Rich Repeat RVT_1 PF00078.27 EQB60020.1 - 2.2e-06 27.3 0.5 5.2e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3837 PF12939.7 EQB60020.1 - 0.086 13.3 0.8 0.26 11.7 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) ALS2CR8 PF15299.6 EQB60020.1 - 0.15 11.9 0.4 0.39 10.6 0.1 1.7 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Rab3-GTPase_cat PF13890.6 EQB60021.1 - 0.093 12.4 0.3 0.093 12.4 0.3 1.8 1 1 1 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit LRR_8 PF13855.6 EQB60024.1 - 1.4e-32 111.2 78.1 2e-08 33.8 9.4 7.8 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EQB60024.1 - 9.4e-31 105.4 98.9 1.1e-06 28.8 7.4 8.9 4 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60024.1 - 2.6e-06 27.1 39.7 0.0018 17.8 5.5 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 EQB60024.1 - 2.7e-06 27.1 70.4 0.19 12.4 0.3 13.7 11 3 2 13 13 13 6 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EQB60024.1 - 8.6e-06 25.7 3.3 15 5.8 0.0 6.4 5 2 1 6 6 6 3 RsmF rRNA methyltransferase first C-terminal domain TEA PF01285.18 EQB60025.1 - 0.078 13.1 0.6 0.51 10.4 0.1 2.5 2 0 0 2 2 2 0 TEA/ATTS domain RVT_1 PF00078.27 EQB60026.1 - 2.2e-11 43.7 2.0 9.6e-11 41.6 0.4 2.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ERp29_N PF07912.13 EQB60026.1 - 0.0056 16.8 0.4 0.24 11.6 0.0 2.6 2 0 0 2 2 2 1 ERp29, N-terminal domain DinI PF06183.13 EQB60026.1 - 0.029 14.7 0.2 19 5.7 0.0 3.4 3 0 0 3 3 3 0 DinI-like family Linker_histone PF00538.19 EQB60026.1 - 0.14 12.5 11.1 4.3 7.8 0.1 5.0 4 0 0 4 4 4 0 linker histone H1 and H5 family LisH PF08513.11 EQB60026.1 - 0.99 9.5 4.9 46 4.2 0.0 4.1 3 0 0 3 3 3 0 LisH D5_N PF08706.11 EQB60028.1 - 0.004 17.4 0.1 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 D5 N terminal like Complex1_LYR PF05347.15 EQB60028.1 - 10 6.3 9.5 0.17 12.0 0.6 2.7 3 0 0 3 3 3 0 Complex 1 protein (LYR family) RabGAP-TBC PF00566.18 EQB60029.1 - 5.8e-05 22.8 3.8 5.8e-05 22.8 3.8 3.1 2 1 1 3 3 3 2 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 EQB60030.1 - 5.6e-13 49.0 22.2 6.3e-08 32.5 5.9 5.9 4 2 2 6 6 6 3 Rab-GTPase-TBC domain Pkinase PF00069.25 EQB60032.1 - 6.9e-06 25.6 0.0 7.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EQB60032.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 Kinase-like WD40 PF00400.32 EQB60033.1 - 0.0066 17.3 1.4 0.031 15.2 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat YIF1 PF03878.15 EQB60034.1 - 1.1e-22 80.8 1.3 2.5e-22 79.6 1.3 1.5 1 1 0 1 1 1 1 YIF1 YL1_C PF08265.11 EQB60034.1 - 1.6e-08 34.2 0.9 3.4e-08 33.1 0.9 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-RVT PF13966.6 EQB60037.1 - 0.0015 19.2 5.6 0.064 14.0 0.6 2.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase TMEM154 PF15102.6 EQB60037.1 - 0.0024 17.8 0.1 0.0057 16.6 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family zinc_ribbon_5 PF13719.6 EQB60037.1 - 0.003 17.3 0.9 2.8 7.8 0.1 2.7 2 0 0 2 2 2 2 zinc-ribbon domain TraF PF13728.6 EQB60037.1 - 0.019 14.8 0.1 10 5.8 0.0 2.7 3 0 0 3 3 3 0 F plasmid transfer operon protein zinc_ribbon_4 PF13717.6 EQB60037.1 - 0.021 14.7 3.0 2.9 7.9 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain BsuBI_PstI_RE PF06616.11 EQB60037.1 - 0.03 13.6 0.1 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain COX2_TM PF02790.15 EQB60037.1 - 0.25 11.5 2.5 0.41 10.8 0.3 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain zf-H2C2_2 PF13465.6 EQB60037.1 - 0.3 11.6 7.1 12 6.5 2.4 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_4 PF14570.6 EQB60037.1 - 0.6 9.9 9.5 4.5 7.1 1.4 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.19 EQB60037.1 - 0.77 9.8 6.7 0.51 10.4 0.3 2.8 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_4 PF13894.6 EQB60037.1 - 0.96 10.5 14.1 59 4.9 3.2 4.9 2 2 0 2 2 2 0 C2H2-type zinc finger PI3K_rbd PF00794.18 EQB60037.1 - 0.98 9.6 7.9 14 5.9 0.2 3.9 4 0 0 4 4 4 0 PI3-kinase family, ras-binding domain Sprouty PF05210.13 EQB60037.1 - 1.3 9.4 14.3 6.5 7.2 3.8 2.9 2 0 0 2 2 2 0 Sprouty protein (Spry) Zn_Tnp_IS1595 PF12760.7 EQB60037.1 - 1.8 8.6 8.5 3.5 7.7 1.2 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rad21_Rec8 PF04824.16 EQB60038.1 - 1.5e-08 33.8 0.1 3.9e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 EQB60038.1 - 0.0036 17.3 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 Segregation and condensation protein ScpA SAC3_GANP PF03399.16 EQB60039.1 - 3.8e-57 193.9 13.1 3.8e-57 193.9 13.1 1.5 2 0 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EQB60039.1 - 0.04 13.9 1.0 0.077 13.0 1.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family HTH_DeoR PF08220.12 EQB60039.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ribosomal_L13 PF00572.18 EQB60040.1 - 0.00017 21.9 2.1 0.11 12.7 0.1 2.9 3 0 0 3 3 3 2 Ribosomal protein L13 DUF5617 PF18493.1 EQB60040.1 - 0.036 14.2 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) DUF643 PF04867.12 EQB60040.1 - 0.19 12.3 6.2 0.25 12.0 4.5 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF643) RRM_1 PF00076.22 EQB60042.1 - 0.00074 19.3 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRG8 PF17068.5 EQB60043.1 - 0.025 14.0 0.6 0.039 13.4 0.6 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial Brix PF04427.18 EQB60044.1 - 0.00019 21.6 0.8 0.00028 21.0 0.8 1.3 1 0 0 1 1 1 1 Brix domain WD40 PF00400.32 EQB60045.1 - 7.5e-20 70.9 9.9 3.1e-08 34.1 0.3 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB60045.1 - 2.2e-11 43.9 4.8 0.00023 21.4 0.2 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EQB60045.1 - 4.5e-05 22.6 0.6 0.00094 18.2 0.4 2.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EQB60045.1 - 0.00089 19.3 0.1 0.51 10.4 0.0 3.6 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EQB60045.1 - 0.0021 17.4 3.9 0.0099 15.2 0.8 2.6 1 1 0 2 2 2 1 WD40-like domain Nbas_N PF15492.6 EQB60045.1 - 0.0052 16.2 0.8 0.011 15.1 0.6 1.5 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal RGS PF00615.19 EQB60045.1 - 0.14 12.4 1.0 0.69 10.2 0.1 2.5 3 0 0 3 3 3 0 Regulator of G protein signaling domain HUN PF08729.10 EQB60046.1 - 2.5e-07 30.6 2.4 5.7e-06 26.2 0.4 2.9 2 1 0 2 2 2 2 HPC2 and ubinuclein domain IMS PF00817.20 EQB60048.1 - 2.4e-18 66.6 0.0 3.5e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family DUF4840 PF16128.5 EQB60048.1 - 0.004 17.2 0.8 0.0054 16.8 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4840) DUF1805 PF08827.11 EQB60048.1 - 0.047 14.0 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Cnn_1N PF07989.11 EQB60048.1 - 0.11 12.7 2.2 0.2 11.8 2.2 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Thymidylate_kin PF02223.17 EQB60049.1 - 3.1e-33 115.0 0.0 3.7e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 EQB60049.1 - 0.0019 18.1 0.5 2 8.2 0.0 3.0 2 2 1 3 3 3 2 Deoxynucleoside kinase AAA_18 PF13238.6 EQB60049.1 - 0.017 15.7 0.6 0.057 14.0 0.3 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EQB60049.1 - 0.06 13.2 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 EQB60049.1 - 0.1 13.0 0.0 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EQB60050.1 - 9.6e-22 77.5 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 EQB60050.1 - 0.047 13.6 0.2 1.4 8.7 0.0 2.3 2 1 0 2 2 2 0 Deoxynucleoside kinase SWIB PF02201.18 EQB60051.1 - 1e-08 34.9 0.5 1e-08 34.9 0.5 2.3 3 0 0 3 3 3 1 SWIB/MDM2 domain NodZ PF05830.11 EQB60051.1 - 0.09 11.6 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Transket_pyr PF02779.24 EQB60052.1 - 4.4e-32 111.2 0.0 5.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EQB60052.1 - 1.7e-28 99.0 0.0 6.3e-28 97.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain Cauli_DNA-bind PF03310.13 EQB60052.1 - 0.022 14.8 0.4 0.16 12.1 0.1 2.2 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Comm PF15957.5 EQB60053.1 - 0.045 14.1 1.4 0.058 13.7 0.3 1.7 2 0 0 2 2 2 0 Commissureless eIF-1a PF01176.19 EQB60054.1 - 3.2e-09 36.4 0.0 6.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_CC_LHEQLE PF14379.6 EQB60056.1 - 0.018 14.7 6.2 0.12 12.1 1.5 2.5 1 1 1 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Actin_micro PF17003.5 EQB60060.1 - 9.6e-45 153.3 25.2 2e-29 102.9 17.5 3.3 1 1 0 2 2 2 2 Putative actin-like family zf-C2H2 PF00096.26 EQB60060.1 - 0.052 14.0 1.3 0.12 12.9 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EQB60060.1 - 0.06 14.2 1.5 0.17 12.8 1.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 EQB60060.1 - 0.54 11.0 6.0 2.6 8.9 0.4 2.7 2 1 1 3 3 3 0 zinc-ribbon family Glycos_transf_2 PF00535.26 EQB60063.1 - 2.5e-22 79.5 0.5 6e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EQB60063.1 - 0.0021 18.0 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Homeodomain PF00046.29 EQB60065.1 - 3.9e-12 45.8 0.6 6.5e-12 45.1 0.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EQB60065.1 - 6.8e-05 22.7 0.2 0.00017 21.4 0.1 1.6 2 0 0 2 2 2 1 Homeobox KN domain HTH_23 PF13384.6 EQB60065.1 - 0.025 14.4 0.1 0.047 13.5 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain PepSY_like PF11396.8 EQB60067.1 - 0.048 14.2 7.9 0.075 13.6 7.2 1.8 1 1 0 1 1 1 0 Putative beta-lactamase-inhibitor-like, PepSY-like S-layer PF07752.11 EQB60068.1 - 0.014 14.5 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 S-layer protein DUF5345 PF17280.2 EQB60068.1 - 0.044 13.8 0.1 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Orn_Arg_deC_N PF02784.16 EQB60069.1 - 0.09 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Thioredoxin_2 PF13098.6 EQB60073.1 - 4.5e-05 23.9 0.1 0.0069 16.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 EQB60073.1 - 5.1e-05 23.2 0.8 5.8e-05 23.0 0.8 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EQB60073.1 - 0.0024 17.6 0.1 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 Redoxin TraF PF13728.6 EQB60073.1 - 0.0045 16.8 0.1 0.0069 16.2 0.1 1.3 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EQB60073.1 - 0.011 15.8 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.6 EQB60073.1 - 0.011 16.0 0.6 1.2 9.5 0.0 2.5 2 1 1 3 3 3 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EQB60073.1 - 0.022 14.5 0.4 0.039 13.7 0.4 1.4 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 EQB60073.1 - 0.028 14.7 0.4 0.057 13.6 0.4 1.7 1 1 0 1 1 1 0 Glutaredoxin Ribosomal_L7Ae PF01248.26 EQB60074.1 - 5.1e-15 55.0 1.3 6.5e-15 54.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNA_pol_Rpb4 PF03874.16 EQB60075.1 - 4e-13 49.8 2.0 4e-13 49.8 2.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2774 PF11242.8 EQB60075.1 - 0.083 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) UQ_con PF00179.26 EQB60076.1 - 2.6e-40 137.3 1.8 2.9e-40 137.1 1.8 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EQB60076.1 - 0.0047 17.2 0.2 0.0065 16.7 0.2 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EQB60076.1 - 0.0087 15.8 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EQB60076.1 - 0.0094 15.8 1.0 0.017 15.0 0.5 1.7 2 0 0 2 2 2 1 UEV domain UFC1 PF08694.11 EQB60076.1 - 0.015 14.9 0.7 0.03 14.0 0.2 1.6 1 1 1 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sugar_tr PF00083.24 EQB60078.1 - 3.1e-24 85.7 20.0 5.6e-18 65.0 17.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EQB60078.1 - 1.2e-15 57.3 26.4 1e-14 54.2 23.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2464 PF10240.9 EQB60079.1 - 0.019 14.6 4.2 0.023 14.3 4.2 1.1 1 0 0 1 1 1 0 Multivesicular body subunit 12 Lipase_GDSL_3 PF14606.6 EQB60079.1 - 0.045 13.9 4.2 0.057 13.6 3.9 1.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MAP17 PF15807.5 EQB60079.1 - 0.056 13.7 0.7 0.056 13.7 0.7 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF1666 PF07891.12 EQB60080.1 - 0.0066 16.2 6.1 0.007 16.1 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1666) YtxH PF12732.7 EQB60080.1 - 1.1 9.8 5.9 1.6 9.4 5.5 1.4 1 1 0 1 1 1 0 YtxH-like protein Nucleoporin_FG PF13634.6 EQB60081.1 - 0.0029 18.4 2.0 0.0043 17.9 2.0 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region DUF2870 PF11069.8 EQB60081.1 - 0.3 11.5 4.6 0.98 9.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Apt1 PF10351.9 EQB60082.1 - 0.33 9.7 22.4 0.55 9.0 22.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Apt1 PF10351.9 EQB60083.1 - 1.5 7.6 23.7 1.8 7.3 23.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain AlgF PF11182.8 EQB60084.1 - 0.052 13.3 3.5 0.12 12.1 3.2 1.9 1 1 1 2 2 2 0 Alginate O-acetyl transferase AlgF Trehalose_PPase PF02358.16 EQB60085.1 - 5.1e-10 38.9 0.0 1.2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase HTH_48 PF17906.1 EQB60088.1 - 0.3 11.2 4.8 9 6.5 0.2 2.8 3 0 0 3 3 3 0 HTH domain in Mos1 transposase MutS_V PF00488.21 EQB60089.1 - 3e-61 206.7 0.0 5e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V AAA_27 PF13514.6 EQB60089.1 - 0.026 14.1 0.0 0.062 12.9 0.0 1.5 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EQB60089.1 - 0.08 13.2 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain MutS_III PF05192.18 EQB60090.1 - 1.5e-09 38.4 0.0 2.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain III MRP-S33 PF08293.11 EQB60090.1 - 0.015 15.5 0.5 2.8 8.3 0.0 3.1 1 1 2 3 3 3 0 Mitochondrial ribosomal subunit S27 Synaptobrevin PF00957.21 EQB60091.1 - 8.5e-10 38.3 0.3 8.5e-10 38.3 0.3 1.9 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 EQB60091.1 - 0.004 17.2 0.5 0.013 15.5 0.3 1.9 2 0 0 2 2 2 1 Regulated-SNARE-like domain RE_TdeIII PF09520.10 EQB60091.1 - 0.019 14.7 0.9 0.026 14.2 0.6 1.4 1 1 0 1 1 1 0 Type II restriction endonuclease, TdeIII Stap_Strp_tox_C PF02876.17 EQB60091.1 - 0.11 12.8 3.1 0.068 13.5 1.0 1.7 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain HSP70 PF00012.20 EQB60092.1 - 3.8e-166 553.8 6.5 8e-92 308.3 0.4 2.7 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EQB60092.1 - 4.1e-11 42.3 0.8 4.6e-05 22.4 0.2 3.2 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 EQB60092.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EQB60092.1 - 0.017 14.4 0.6 2.6 7.2 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Adaptin_binding PF10199.9 EQB60092.1 - 0.038 14.6 1.3 0.087 13.4 1.3 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DDR PF08841.10 EQB60092.1 - 0.067 12.2 0.0 0.52 9.2 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF3289 PF11692.8 EQB60092.1 - 0.18 11.3 1.5 0.35 10.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3289) EutA PF06277.11 EQB60092.1 - 1.3 7.8 6.0 0.67 8.7 0.1 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutA V-ATPase_C PF03223.15 EQB60093.1 - 7.6e-23 81.5 17.3 1.5e-22 80.6 17.3 1.4 1 1 0 1 1 1 1 V-ATPase subunit C Tup_N PF08581.10 EQB60093.1 - 0.043 14.1 2.8 0.067 13.5 1.3 2.2 2 0 0 2 2 2 0 Tup N-terminal Myb_DNA-bind_7 PF15963.5 EQB60093.1 - 0.073 13.0 1.2 0.21 11.5 1.2 1.9 1 0 0 1 1 1 0 Myb DNA-binding like HECT PF00632.25 EQB60094.1 - 2.8e-57 194.5 0.2 5.3e-41 141.1 0.0 2.5 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) ABC2_membrane PF01061.24 EQB60095.1 - 4.1e-13 49.2 5.0 6e-13 48.7 5.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EQB60095.1 - 2.2e-12 47.7 0.3 3e-12 47.2 0.3 1.2 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EQB60095.1 - 7.8e-06 25.9 0.4 1.6e-05 24.9 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EQB60095.1 - 2.4e-05 24.9 1.3 3.8e-05 24.3 1.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EQB60095.1 - 0.00015 21.4 0.2 0.00041 20.0 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EQB60095.1 - 0.00032 21.1 0.2 0.00077 19.8 0.2 1.8 1 0 0 1 1 1 1 RNA helicase ABC2_membrane_3 PF12698.7 EQB60095.1 - 0.0004 19.6 5.6 0.0004 19.6 5.6 1.9 1 1 1 2 2 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 EQB60095.1 - 0.00045 20.7 0.0 0.00062 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EQB60095.1 - 0.0018 18.8 0.1 0.0029 18.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EQB60095.1 - 0.0024 18.1 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EQB60095.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EQB60095.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 EQB60095.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EQB60095.1 - 0.012 15.2 0.2 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EQB60095.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_21 PF13304.6 EQB60095.1 - 0.017 14.9 1.8 0.028 14.2 1.8 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EQB60095.1 - 0.019 15.4 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EQB60095.1 - 0.029 14.1 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EQB60095.1 - 0.041 14.1 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EQB60095.1 - 0.043 12.9 0.2 0.061 12.4 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EQB60095.1 - 0.047 13.6 0.2 0.079 12.9 0.2 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 EQB60095.1 - 0.063 13.0 0.1 0.075 12.8 0.1 1.3 1 1 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 EQB60095.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 EQB60095.1 - 0.089 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 EQB60095.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EQB60095.1 - 0.14 12.3 0.5 0.2 11.8 0.5 1.5 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EQB60096.1 - 2.4e-49 168.3 0.4 3e-49 168.0 0.4 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EQB60096.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EQB60096.1 - 0.00025 21.6 0.3 0.00058 20.4 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EQB60096.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EQB60096.1 - 0.0019 17.9 0.1 0.1 12.3 0.0 2.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EQB60096.1 - 0.0034 16.6 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 EQB60096.1 - 0.0049 16.9 1.4 0.015 15.3 0.1 2.3 2 1 1 3 3 3 1 AAA domain SRP54 PF00448.22 EQB60096.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EQB60096.1 - 0.013 15.5 0.1 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CLP1_P PF16575.5 EQB60096.1 - 0.02 14.7 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 EQB60096.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EQB60096.1 - 0.069 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EQB60096.1 - 0.095 12.3 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EQB60096.1 - 0.096 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 EQB60096.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EQB60096.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EQB60096.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EQB60096.1 - 0.18 11.7 2.1 9.5 6.1 0.0 3.1 2 1 0 3 3 3 0 AAA domain SPT16 PF08644.11 EQB60098.1 - 3.1e-13 50.2 4.2 3.1e-13 50.2 4.2 1.9 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EQB60098.1 - 3.2e-06 27.0 0.0 3.2e-06 27.0 0.0 2.5 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EQB60098.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase family M24 Ribosomal_S20p PF01649.18 EQB60098.1 - 0.053 14.2 0.3 0.19 12.4 0.3 1.9 1 0 0 1 1 1 0 Ribosomal protein S20 DUF4451 PF14616.6 EQB60099.1 - 5.6e-17 62.1 7.9 1.6e-16 60.6 7.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) Rubredoxin_2 PF18073.1 EQB60099.1 - 0.0012 18.6 1.9 0.13 12.0 0.2 2.5 2 0 0 2 2 2 2 Rubredoxin metal binding domain zf-RING-like PF08746.11 EQB60099.1 - 0.11 12.9 0.7 0.11 12.9 0.7 2.0 2 0 0 2 2 2 0 RING-like domain zf-C2H2_4 PF13894.6 EQB60099.1 - 0.44 11.5 6.8 0.68 10.9 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Tyrosinase PF00264.20 EQB60100.1 - 6.4e-29 101.8 6.1 4.7e-14 53.2 0.2 2.6 2 1 0 3 3 3 2 Common central domain of tyrosinase YebG PF07130.12 EQB60100.1 - 0.064 13.1 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 YebG protein WD40 PF00400.32 EQB60101.1 - 1.6e-39 133.1 12.8 3.7e-06 27.6 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat WD40_like PF17005.5 EQB60101.1 - 7.5e-13 48.5 13.9 1e-07 31.6 1.6 2.9 1 1 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 EQB60101.1 - 1.4e-06 28.3 1.8 0.03 14.4 0.1 4.7 2 1 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Vps16_N PF04841.13 EQB60101.1 - 0.0035 16.2 0.6 0.021 13.6 0.1 2.2 1 1 1 2 2 2 1 Vps16, N-terminal region RAB3GAP2_N PF14655.6 EQB60101.1 - 0.027 13.7 0.6 0.17 11.1 0.0 2.4 3 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NLE PF08154.12 EQB60101.1 - 0.057 13.9 1.0 0.16 12.5 1.0 1.8 1 1 0 1 1 1 0 NLE (NUC135) domain RNA_pol_Rpb2_6 PF00562.28 EQB60102.1 - 5.7e-96 321.9 2.3 4.1e-69 233.5 0.1 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EQB60102.1 - 7.4e-21 74.4 0.2 1.7e-20 73.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EQB60102.1 - 9.5e-17 60.9 0.1 1.9e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EQB60102.1 - 4.1e-08 33.4 0.1 1.2e-07 31.9 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_6 PF00562.28 EQB60103.1 - 1.4e-29 103.4 0.1 1.4e-29 103.4 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 EQB60103.1 - 6.3e-28 96.8 0.0 1.5e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EQB60103.1 - 3.5e-15 56.1 0.3 7.2e-15 55.1 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EQB60103.1 - 4.6e-08 33.2 0.7 1.3e-07 31.7 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_6 PF00562.28 EQB60104.1 - 3.3e-53 181.2 0.1 7.2e-53 180.1 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EQB60104.1 - 1.7e-21 76.4 0.2 3.7e-21 75.3 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 HD_assoc PF13286.6 EQB60105.1 - 0.7 10.5 3.5 13 6.4 0.4 2.5 1 1 1 2 2 2 0 Phosphohydrolase-associated domain Complex1_LYR PF05347.15 EQB60105.1 - 1.3 9.1 14.7 20 5.3 0.6 4.1 3 1 1 4 4 4 0 Complex 1 protein (LYR family) Nebulin PF00880.18 EQB60105.1 - 1.5 8.8 10.1 39 4.3 0.1 4.2 4 0 0 4 4 4 0 Nebulin repeat Chromosome_seg PF13889.6 EQB60105.1 - 1.7 8.9 9.6 24 5.2 0.2 4.0 1 1 4 5 5 5 0 Chromosome segregation during meiosis GDI PF00996.18 EQB60105.1 - 1.9 6.9 8.2 2.1 6.8 8.2 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Serpin PF00079.20 EQB60107.1 - 4.4e-82 276.3 17.9 5.3e-82 276.1 17.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF4905 PF16248.5 EQB60108.1 - 0.047 13.6 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) SIR2 PF02146.17 EQB60109.1 - 1.4e-34 119.6 0.4 2.2e-34 118.9 0.4 1.3 1 0 0 1 1 1 1 Sir2 family AAA PF00004.29 EQB60110.1 - 4.6e-39 133.9 0.0 7.4e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EQB60110.1 - 3.9e-11 42.6 0.0 1.4e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EQB60110.1 - 7.7e-07 29.0 0.1 1.7e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EQB60110.1 - 6.1e-06 26.6 1.3 0.02 15.2 0.1 3.1 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 EQB60110.1 - 2e-05 24.6 0.2 0.0002 21.4 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EQB60110.1 - 3.7e-05 23.5 0.0 7.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EQB60110.1 - 0.00024 21.3 0.0 0.00047 20.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 EQB60110.1 - 0.0013 18.1 0.1 1 8.8 0.0 2.5 1 1 1 2 2 2 2 Bacterial TniB protein AAA_16 PF13191.6 EQB60110.1 - 0.0028 18.0 0.1 0.15 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EQB60110.1 - 0.0064 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EQB60110.1 - 0.015 14.5 0.5 0.068 12.4 0.1 2.0 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_25 PF13481.6 EQB60110.1 - 0.032 13.8 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EQB60110.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EQB60110.1 - 0.058 13.7 0.3 0.15 12.4 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EQB60110.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EQB60110.1 - 0.074 12.6 0.3 0.19 11.2 0.3 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EQB60110.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EQB60110.1 - 0.098 12.4 0.9 0.27 10.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain SRI PF08236.11 EQB60110.1 - 0.11 12.7 1.3 0.84 9.9 0.1 2.1 1 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain AAA_18 PF13238.6 EQB60110.1 - 0.12 12.9 1.5 0.25 11.9 0.5 2.2 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EQB60110.1 - 0.14 11.4 0.8 16 4.8 0.3 2.5 1 1 1 2 2 2 0 KaiC AAA_11 PF13086.6 EQB60110.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain DRE2_N PF16803.5 EQB60111.1 - 0.045 14.0 0.5 0.11 12.7 0.5 1.7 1 1 1 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus Arf PF00025.21 EQB60112.1 - 5.6e-32 110.6 0.1 1.7e-31 109.0 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EQB60112.1 - 3e-15 56.5 0.0 4.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EQB60112.1 - 4.3e-12 45.9 0.0 5.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EQB60112.1 - 5.7e-11 42.2 1.7 1.1e-06 28.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EQB60112.1 - 1.3e-09 37.8 0.1 1.9e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EQB60112.1 - 1.2e-07 31.8 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EQB60112.1 - 0.00057 19.4 0.0 0.001 18.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EQB60112.1 - 0.0049 16.4 0.1 0.2 11.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 EQB60112.1 - 0.023 14.6 0.4 0.034 14.1 0.4 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EQB60112.1 - 0.037 13.2 0.0 0.044 13.0 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain FeoB_N PF02421.18 EQB60112.1 - 0.05 13.1 0.3 0.069 12.7 0.3 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B FleQ PF06490.11 EQB60112.1 - 0.11 12.9 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ AAA_22 PF13401.6 EQB60112.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_S9 PF00380.19 EQB60113.1 - 2.9e-22 79.4 0.4 3.6e-22 79.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF1244 PF06844.11 EQB60113.1 - 0.15 12.3 2.1 0.16 12.1 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1244) DUF4840 PF16128.5 EQB60113.1 - 0.25 11.4 3.8 0.68 10.0 3.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4840) Ribosomal_L13e PF01294.18 EQB60114.1 - 1.7e-45 155.1 5.4 1.8e-45 155.0 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e tRNA_synthFbeta PF17759.1 EQB60116.1 - 4.2e-30 104.8 0.0 6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 EQB60116.1 - 2.8e-13 50.0 0.6 7.6e-13 48.6 0.6 1.8 1 0 0 1 1 1 1 tRNA synthetase B5 domain B3_4 PF03483.17 EQB60116.1 - 4.8e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain RNA_pol_Rpb1_1 PF04997.12 EQB60117.1 - 2.1e-103 345.9 0.0 2.1e-103 345.9 0.0 2.8 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EQB60117.1 - 1.4e-91 306.7 0.6 2.5e-91 305.8 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EQB60117.1 - 1.9e-74 249.4 0.2 6.5e-74 247.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EQB60117.1 - 1.4e-44 151.7 0.1 4.6e-44 150.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EQB60117.1 - 6.5e-38 129.0 0.7 6.5e-38 129.0 0.7 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 EQB60117.1 - 4.5e-29 101.2 2.8 1.2e-28 99.8 2.8 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_6 PF04992.14 EQB60117.1 - 2.8e-17 63.2 8.7 2.8e-17 63.2 8.7 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_R PF05001.13 EQB60117.1 - 1.4e-14 53.5 299.0 0.37 11.3 16.2 13.6 2 1 4 15 15 15 13 RNA polymerase Rpb1 C-terminal repeat Adaptin_N PF01602.20 EQB60118.1 - 2.6e-15 56.0 13.2 2.1e-14 53.0 12.1 2.1 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EQB60118.1 - 0.00053 20.1 2.0 0.0016 18.6 2.0 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain RTP1_C1 PF10363.9 EQB60118.1 - 0.0083 16.3 3.0 2.8 8.2 0.0 3.9 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RFC1 PF08519.12 EQB60118.1 - 0.065 13.4 4.2 0.14 12.3 0.3 2.9 2 1 0 2 2 2 0 Replication factor RFC1 C terminal domain Xpo1 PF08389.12 EQB60118.1 - 0.81 9.7 7.9 4.9 7.2 0.2 3.8 3 1 1 4 4 4 0 Exportin 1-like protein GCS PF03074.16 EQB60120.1 - 3.3e-35 122.1 0.0 4e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase BRCT PF00533.26 EQB60121.1 - 1.7e-17 63.6 21.3 0.00017 21.9 1.3 5.3 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EQB60121.1 - 6.6e-13 48.4 11.1 7.5e-10 38.6 0.1 4.0 4 1 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EQB60121.1 - 1.6e-11 44.0 0.8 0.00011 22.1 0.0 4.0 4 0 0 4 4 4 2 twin BRCT domain BRCT_2 PF16589.5 EQB60121.1 - 1.8e-11 44.3 13.6 1.1e-09 38.5 1.0 3.4 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EQB60121.1 - 1.5e-10 41.2 0.3 1.1e-05 25.6 0.0 3.6 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain ThiF PF00899.21 EQB60122.1 - 8.9e-42 143.1 0.7 1e-41 142.9 0.7 1.1 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 EQB60122.1 - 0.00098 19.5 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EQB60122.1 - 0.03 14.9 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EQB60122.1 - 0.033 14.4 0.2 0.07 13.4 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EQB60122.1 - 0.046 14.2 0.1 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EQB60122.1 - 0.062 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 EQB60122.1 - 0.17 11.0 0.0 0.46 9.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase V-ATPase_G PF03179.15 EQB60123.1 - 0.00023 21.7 11.4 0.00027 21.4 11.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PPP1R35_C PF15503.6 EQB60123.1 - 0.011 15.5 5.4 0.013 15.3 5.4 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus T3SSipB PF16535.5 EQB60123.1 - 0.21 12.1 6.0 2.3 8.7 1.0 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB U62_UL91 PF17442.2 EQB60124.1 - 0.019 14.9 0.8 0.045 13.7 0.3 1.9 1 1 1 2 2 2 0 Functional domain of U62 and UL91 proteins DUF3496 PF12001.8 EQB60124.1 - 0.086 13.2 2.0 0.088 13.2 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) CdAMP_rec PF06153.11 EQB60124.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Cyclic-di-AMP receptor E2F_CC-MB PF16421.5 EQB60125.1 - 4.8e-16 58.9 0.3 8.8e-16 58.1 0.2 1.4 1 1 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 EQB60125.1 - 1.6e-14 53.7 0.1 3.1e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Orthopox_A49R PF06489.11 EQB60125.1 - 0.019 15.2 0.3 0.029 14.6 0.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus A49R protein Helicase_C PF00271.31 EQB60126.1 - 3.8e-19 69.1 1.3 4.4e-19 68.9 0.2 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EQB60126.1 - 2.1e-05 24.3 7.3 3.4e-05 23.6 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EQB60126.1 - 5.7e-05 22.4 0.5 9.9e-05 21.7 0.3 1.5 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 EQB60126.1 - 0.00027 20.8 8.5 0.00045 20.1 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EQB60126.1 - 0.00051 19.8 8.1 0.001 18.9 8.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EQB60126.1 - 0.00067 19.5 9.4 0.0011 18.8 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EQB60126.1 - 0.0011 19.2 9.2 0.0019 18.5 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EQB60126.1 - 0.0097 15.9 4.2 0.0097 15.9 4.2 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EQB60126.1 - 0.017 14.9 10.0 0.033 14.1 10.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HAD PF12710.7 EQB60126.1 - 0.064 13.6 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-RING_10 PF16685.5 EQB60126.1 - 0.45 10.7 4.2 0.95 9.6 4.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 SNF2_N PF00176.23 EQB60127.1 - 7.3e-13 47.9 0.6 5.9e-12 45.0 0.6 2.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain Ribosomal_L6 PF00347.23 EQB60128.1 - 2.6e-07 31.2 0.0 0.00022 21.8 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L24e PF01246.20 EQB60129.1 - 6.9e-31 106.3 5.5 1.4e-30 105.3 5.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e RNase_J_C PF17770.1 EQB60129.1 - 0.17 12.9 3.0 0.54 11.3 0.1 2.5 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain DUF5320 PF17253.2 EQB60129.1 - 0.3 12.2 1.9 0.44 11.7 0.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) CDC45 PF02724.14 EQB60130.1 - 1.8e-05 23.3 0.4 2.3e-05 22.9 0.4 1.1 1 0 0 1 1 1 1 CDC45-like protein DEAD PF00270.29 EQB60133.1 - 4e-35 121.2 1.0 9.7e-35 119.9 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EQB60133.1 - 1.9e-28 99.0 1.9 2e-26 92.5 0.1 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EQB60133.1 - 2.8e-13 50.2 0.2 5.5e-13 49.3 0.2 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EQB60133.1 - 9.3e-06 25.4 0.2 1.7e-05 24.5 0.2 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 EQB60133.1 - 0.0053 16.1 0.7 0.028 13.7 0.4 2.4 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SWI2_SNF2 PF18766.1 EQB60133.1 - 0.0053 16.5 1.6 0.0059 16.3 0.4 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 EQB60133.1 - 0.13 12.6 1.4 0.37 11.1 1.3 1.9 1 1 0 1 1 1 0 AAA domain eIF3_subunit PF08597.10 EQB60134.1 - 0.0056 16.6 1.9 0.0081 16.1 1.9 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit NAGLU_C PF12972.7 EQB60134.1 - 0.03 13.8 0.1 0.032 13.8 0.1 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Ribosomal_S8e PF01201.22 EQB60136.1 - 2.4e-34 118.4 11.7 1e-17 64.6 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein S8e HAD_2 PF13419.6 EQB60136.1 - 0.045 13.8 0.0 0.063 13.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PAZ_siRNAbind PF12212.8 EQB60137.1 - 0.69 9.7 10.0 0.1 12.4 5.1 2.0 2 1 0 2 2 2 0 PAZ domain LRR_2 PF07723.13 EQB60137.1 - 1.1 10.1 4.3 0.44 11.3 0.6 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat DDE_Tnp_1_7 PF13843.6 EQB60140.1 - 1.6e-06 27.7 0.4 2.3e-06 27.2 0.4 1.2 1 0 0 1 1 1 1 Transposase IS4 Stm1_N PF09598.10 EQB60140.1 - 0.043 14.7 0.1 0.074 13.9 0.1 1.4 1 0 0 1 1 1 0 Stm1 YL1 PF05764.13 EQB60140.1 - 0.074 13.2 6.2 0.098 12.8 6.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CH_2 PF06294.11 EQB60140.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein RVT_1 PF00078.27 EQB60142.1 - 1.5e-24 86.8 0.0 2.2e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BsuBI_PstI_RE PF06616.11 EQB60143.1 - 0.00075 18.8 0.2 0.00091 18.5 0.2 1.2 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain Peptidase_M23_N PF18421.1 EQB60143.1 - 0.012 15.5 0.4 0.019 14.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase family M23 N-terminal domain HSDR_N_2 PF13588.6 EQB60143.1 - 0.016 15.2 3.0 0.023 14.7 2.3 1.6 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) MTES_1575 PF18741.1 EQB60143.1 - 0.079 13.1 0.4 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 REase_MTES_1575 TraF PF13728.6 EQB60143.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein adh_short PF00106.25 EQB60144.1 - 4.2e-18 65.5 0.2 9.6e-16 57.8 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EQB60144.1 - 0.00011 21.8 0.0 0.0013 18.4 0.0 2.1 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EQB60144.1 - 0.00014 21.8 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 KR domain HIM1 PF08732.10 EQB60144.1 - 0.0026 17.3 0.4 0.0043 16.6 0.4 1.4 1 0 0 1 1 1 1 HIM1 Polysacc_synt_2 PF02719.15 EQB60144.1 - 0.027 13.6 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EQB60144.1 - 0.058 13.7 0.1 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain NIF PF03031.18 EQB60145.1 - 0.00055 19.7 2.7 0.00057 19.7 1.9 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Gram_pos_anchor PF00746.21 EQB60145.1 - 0.068 13.1 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TLC PF03219.14 EQB60147.1 - 1.2e-49 169.4 31.6 1.3e-49 169.2 31.6 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter HemY_N PF07219.13 EQB60147.1 - 0.19 11.9 4.1 0.94 9.7 0.0 3.5 3 0 0 3 3 3 0 HemY protein N-terminus Proteasome PF00227.26 EQB60148.1 - 4.7e-19 68.6 0.0 5.4e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EQB60148.1 - 6.2e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pkinase PF00069.25 EQB60149.1 - 1.6e-33 116.2 2.5 2.1e-33 115.8 2.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60149.1 - 8.2e-19 67.9 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB60149.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like SbcCD_C PF13558.6 EQB60150.1 - 0.00092 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Prefoldin_2 PF01920.20 EQB60150.1 - 0.0088 16.0 8.3 0.0088 16.0 8.3 4.6 2 1 1 3 3 3 1 Prefoldin subunit ApoB100_C PF12491.8 EQB60150.1 - 0.045 13.7 2.6 0.064 13.2 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal SMC_N PF02463.19 EQB60150.1 - 0.23 10.9 25.6 0.91 8.9 25.6 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF2309 PF10070.9 EQB60150.1 - 0.23 9.7 0.4 0.32 9.3 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) AAA_23 PF13476.6 EQB60151.1 - 1.7e-23 84.2 19.5 1.7e-23 84.2 19.5 2.5 1 1 1 2 2 1 1 AAA domain SMC_N PF02463.19 EQB60151.1 - 6e-08 32.4 1.7 6e-08 32.4 1.7 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EQB60151.1 - 0.00014 21.5 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EQB60151.1 - 0.0013 18.6 3.2 0.0013 18.6 3.2 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EQB60151.1 - 0.002 18.5 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EQB60151.1 - 0.014 14.7 0.1 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 EQB60151.1 - 0.015 15.5 0.0 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EQB60151.1 - 0.045 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EQB60151.1 - 0.067 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EQB60151.1 - 0.18 12.2 0.1 0.56 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EQB60151.1 - 0.26 11.2 0.0 0.26 11.2 0.0 2.5 4 0 0 4 4 4 0 RsgA GTPase ABC_tran PF00005.27 EQB60151.1 - 0.66 10.5 17.5 44 4.6 17.5 2.8 1 1 0 1 1 1 0 ABC transporter AAA_15 PF13175.6 EQB60151.1 - 0.84 9.3 67.8 0.023 14.4 57.3 2.0 1 1 1 2 2 1 0 AAA ATPase domain DUF4296 PF14129.6 EQB60152.1 - 0.0048 17.5 4.3 0.021 15.4 4.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4296) YcxB PF14317.6 EQB60153.1 - 1.1e-05 25.0 1.1 2.1e-05 24.1 1.1 1.5 1 0 0 1 1 1 1 YcxB-like protein DUF1699 PF08004.11 EQB60153.1 - 0.43 10.3 3.9 0.27 10.9 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1699) MutS_III PF05192.18 EQB60154.1 - 0.0014 18.8 12.7 0.008 16.4 12.7 2.1 1 1 0 1 1 1 1 MutS domain III Inos-1-P_synth PF01658.17 EQB60158.1 - 0.2 11.9 0.2 0.2 11.9 0.2 2.0 2 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase TraF PF13728.6 EQB60159.1 - 0.1 12.4 0.1 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Med14 PF08638.11 EQB60160.1 - 0.016 14.6 0.2 0.025 14.0 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit MED14 Poty_coat PF00767.18 EQB60160.1 - 0.077 12.6 4.0 0.33 10.5 0.4 2.1 1 1 0 2 2 2 0 Potyvirus coat protein Rhodanese PF00581.20 EQB60163.1 - 2.9e-14 53.5 0.1 1.2e-13 51.5 0.1 2.1 2 1 0 2 2 2 1 Rhodanese-like domain Ras PF00071.22 EQB60164.1 - 1.1e-37 129.2 0.4 1.3e-37 128.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB60164.1 - 8.7e-30 103.4 0.3 1.1e-29 103.1 0.3 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB60164.1 - 9.9e-12 44.7 0.1 1.2e-11 44.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EQB60164.1 - 1.6e-07 31.4 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EQB60164.1 - 4.6e-05 22.9 0.1 5.4e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EQB60164.1 - 0.00012 21.6 0.0 0.00013 21.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EQB60164.1 - 0.0023 18.2 0.0 0.0035 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EQB60164.1 - 0.0023 17.5 0.1 0.012 15.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EQB60164.1 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.6 1 1 1 2 2 2 1 RsgA GTPase Septin PF00735.18 EQB60164.1 - 0.0026 17.1 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_16 PF13191.6 EQB60164.1 - 0.0046 17.3 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EQB60164.1 - 0.0048 16.9 0.0 0.0065 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EQB60164.1 - 0.0065 16.8 0.1 0.015 15.6 0.1 1.8 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 EQB60164.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 1.8 2 1 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 EQB60164.1 - 0.0079 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EQB60164.1 - 0.026 14.5 0.2 0.038 14.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EQB60164.1 - 0.032 14.1 0.2 0.041 13.8 0.2 1.0 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 EQB60164.1 - 0.033 13.1 0.1 0.32 9.8 0.0 2.0 1 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 EQB60164.1 - 0.034 13.9 0.1 0.048 13.4 0.1 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EQB60164.1 - 0.068 13.7 0.1 0.079 13.5 0.1 1.3 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 EQB60164.1 - 0.072 13.5 0.0 0.09 13.2 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EQB60164.1 - 0.089 13.0 0.0 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EQB60164.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B 7TM_GPCR_Sra PF02117.16 EQB60164.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra AAA_33 PF13671.6 EQB60164.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain FCP1_C PF09309.10 EQB60165.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PGM_PMM_II PF02879.16 EQB60165.1 - 0.18 12.4 0.2 0.59 10.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF2207 PF09972.9 EQB60165.1 - 0.34 9.6 28.4 0.013 14.3 16.3 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) gag-asp_proteas PF13975.6 EQB60166.1 - 5.6e-08 33.2 0.0 8.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EQB60166.1 - 2.4e-06 28.1 0.0 3.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EQB60166.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4322 PF14210.6 EQB60166.1 - 0.03 14.2 0.7 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) Endonuclease_NS PF01223.23 EQB60168.1 - 0.049 13.4 0.3 0.15 11.8 0.3 1.8 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease KRAB PF01352.27 EQB60168.1 - 0.052 13.2 0.7 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 KRAB box DPPIV_rep PF18811.1 EQB60168.1 - 0.077 13.0 1.6 0.32 11.0 1.1 2.5 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region ESP PF16590.5 EQB60169.1 - 0.0049 17.1 1.7 0.0088 16.3 1.7 1.4 1 0 0 1 1 1 1 Exocrine gland-secreting peptide NdhM PF10664.9 EQB60169.1 - 0.01 16.1 0.6 0.014 15.6 0.6 1.4 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Haemocyan_bet_s PF14830.6 EQB60169.1 - 0.012 15.5 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 0 Haemocyanin beta-sandwich Ago_N_1 PF18351.1 EQB60169.1 - 0.051 14.0 2.4 0.063 13.7 1.7 1.5 1 1 0 1 1 1 0 Fungal Argonaute N-terminal domain BLM10_N PF16547.5 EQB60170.1 - 0.11 12.7 1.1 0.74 10.1 0.1 2.6 1 1 1 2 2 2 0 Proteasome-substrate-size regulator, N-terminal Topoisom_bac PF01131.20 EQB60172.1 - 2.8e-22 79.3 0.2 8.3e-17 61.3 0.0 3.1 3 0 0 3 3 3 3 DNA topoisomerase Topoisom_bac PF01131.20 EQB60173.1 - 5.5e-20 71.8 0.0 9.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EQB60173.1 - 4.8e-14 52.4 0.7 1.7e-13 50.7 0.1 2.1 2 0 0 2 2 2 1 Toprim domain RNase_HII PF01351.18 EQB60174.1 - 1e-32 113.6 1.3 1.1e-16 61.3 0.0 4.0 4 0 0 4 4 4 3 Ribonuclease HII BsuBI_PstI_RE PF06616.11 EQB60175.1 - 0.21 10.9 2.0 0.5 9.6 0.5 2.3 2 1 0 3 3 3 0 BsuBI/PstI restriction endonuclease domain zf-RVT PF13966.6 EQB60175.1 - 0.24 12.1 1.5 0.42 11.3 0.6 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 EQB60176.1 - 4.7e-11 42.6 0.1 7.1e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CofC PF01983.16 EQB60176.1 - 0.045 12.9 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Guanylyl transferase CofC like MUG113 PF13455.6 EQB60177.1 - 0.0092 16.6 0.5 0.4 11.4 0.2 2.5 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 ubiquitin PF00240.23 EQB60179.1 - 0.14 12.0 3.5 5.2 6.9 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin family DUF2373 PF10180.9 EQB60180.1 - 0.0038 17.0 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Selenoprotein_S PF06936.11 EQB60181.1 - 0.23 11.2 4.3 2.7 7.7 0.7 2.4 1 1 1 2 2 2 0 Selenoprotein S (SelS) Bromodomain PF00439.25 EQB60182.1 - 1.8e-15 56.7 0.7 3.7e-15 55.7 0.7 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP_like PF17027.5 EQB60182.1 - 4.2e-05 23.7 1.1 0.00011 22.3 0.2 2.0 2 0 0 2 2 2 1 Histone-fold protein RELT PF12606.8 EQB60182.1 - 0.0069 15.4 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 Ribosomal_L16 PF00252.18 EQB60183.1 - 1.2e-32 112.7 0.1 1.6e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e A1_Propeptide PF07966.12 EQB60183.1 - 0.35 10.8 2.2 7 6.6 0.1 2.7 2 0 0 2 2 2 0 A1 Propeptide ABC2_membrane_3 PF12698.7 EQB60184.1 - 0.41 9.7 1.8 0.46 9.5 1.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 EQB60185.1 - 0.45 9.6 2.2 0.49 9.4 2.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Proteasome PF00227.26 EQB60186.1 - 1.3e-25 90.0 0.0 1.6e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EQB60186.1 - 0.026 14.2 0.0 0.08 12.6 0.0 1.9 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature SBDS PF01172.18 EQB60187.1 - 1e-19 70.4 1.0 2.3e-19 69.2 1.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CitMHS_2 PF16980.5 EQB60187.1 - 0.077 11.6 0.2 0.094 11.4 0.2 1.1 1 0 0 1 1 1 0 Putative citrate transport DUF2540 PF10802.8 EQB60187.1 - 0.99 9.5 7.6 0.22 11.6 2.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2540) Pkinase PF00069.25 EQB60188.1 - 7.4e-36 123.9 6.1 5.2e-35 121.1 6.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60188.1 - 1.1e-22 80.6 0.3 1.9e-22 79.8 0.3 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase zf-CCCH_4 PF18044.1 EQB60189.1 - 2.1e-06 27.4 3.7 5.5e-06 26.0 3.7 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EQB60189.1 - 1.3e-05 25.0 8.7 1.3e-05 25.0 8.7 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EQB60189.1 - 0.00019 21.3 3.0 0.00037 20.3 3.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EQB60189.1 - 0.0002 22.0 0.2 0.0002 22.0 0.2 3.6 2 1 3 5 5 5 1 Torus domain Bromodomain PF00439.25 EQB60192.1 - 1.7e-22 79.2 2.9 2.3e-22 78.9 0.9 2.2 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 EQB60192.1 - 4.8e-11 42.7 0.6 1.2e-10 41.4 0.6 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Fib_alpha PF08702.10 EQB60192.1 - 3.7 7.7 6.8 0.57 10.4 1.1 2.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Spt4 PF06093.13 EQB60193.1 - 3.1e-18 65.7 1.1 4e-18 65.3 1.1 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Cyclin_N PF00134.23 EQB60194.1 - 1.7e-05 24.6 1.5 2.6e-05 23.9 1.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EQB60194.1 - 0.0014 19.0 2.1 0.0019 18.6 2.1 1.3 1 0 0 1 1 1 1 Cyclin RtcB PF01139.17 EQB60195.1 - 1.6e-44 152.7 0.5 2.6e-43 148.8 0.5 2.0 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB YbjN PF10722.9 EQB60195.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator RtcB PF01139.17 EQB60196.1 - 1.6e-46 159.4 0.0 1.8e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Ada3 PF10198.9 EQB60197.1 - 0.00039 20.6 6.4 0.00075 19.7 6.4 1.7 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 CBFD_NFYB_HMF PF00808.23 EQB60199.1 - 8.6e-20 70.8 1.0 1.1e-19 70.5 1.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EQB60199.1 - 0.032 14.2 0.1 0.056 13.5 0.1 1.4 1 1 0 1 1 1 0 Bromodomain associated Cpn60_TCP1 PF00118.24 EQB60200.1 - 8.9e-93 311.5 5.5 9.9e-34 116.8 0.4 3.0 1 1 2 3 3 3 3 TCP-1/cpn60 chaperonin family Tcp10_C PF07202.13 EQB60201.1 - 0.0001 22.3 3.9 0.00018 21.5 3.9 1.4 1 1 0 1 1 1 1 T-complex protein 10 C-terminus PAS_3 PF08447.12 EQB60201.1 - 0.0042 17.3 0.1 0.0072 16.6 0.1 1.4 1 0 0 1 1 1 1 PAS fold DUF903 PF06004.12 EQB60201.1 - 0.01 15.7 1.4 0.03 14.2 0.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF903) DUF3261 PF11659.8 EQB60201.1 - 0.17 11.7 0.3 0.25 11.2 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) WD40 PF00400.32 EQB60202.1 - 1.9e-11 44.3 12.1 0.01 16.7 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB60202.1 - 0.00028 21.1 0.1 1.5 9.1 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S32 PF05579.13 EQB60202.1 - 0.042 13.0 0.1 0.082 12.1 0.1 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 RNA_pol_Rpc34 PF05158.12 EQB60203.1 - 3.2e-43 148.4 9.7 3.3e-42 145.1 9.7 1.9 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 EQB60203.1 - 0.00094 19.5 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator B-block_TFIIIC PF04182.12 EQB60203.1 - 0.003 17.7 0.5 0.003 17.7 0.5 2.3 2 1 0 2 2 2 1 B-block binding subunit of TFIIIC RPA_C PF08784.11 EQB60203.1 - 0.005 17.5 0.4 0.035 14.7 0.1 2.2 2 0 0 2 2 2 1 Replication protein A C terminal DUF1854 PF08909.11 EQB60203.1 - 0.0072 16.1 0.2 0.015 15.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1854) TFIIE_alpha PF02002.17 EQB60203.1 - 0.5 10.3 8.7 0.08 12.8 0.9 2.9 2 2 1 3 3 3 0 TFIIE alpha subunit SRP54 PF00448.22 EQB60204.1 - 2.1e-50 171.1 0.0 2.8e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EQB60204.1 - 3.2e-06 26.3 0.0 5.9e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EQB60204.1 - 3e-05 24.1 0.3 0.095 12.8 0.0 2.4 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EQB60204.1 - 0.00064 20.2 0.1 0.0027 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EQB60204.1 - 0.0016 18.5 0.5 0.016 15.3 0.5 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 EQB60204.1 - 0.0023 17.9 0.1 0.21 11.5 0.1 2.7 1 1 0 1 1 1 1 NTPase RsgA_GTPase PF03193.16 EQB60204.1 - 0.0038 17.2 0.8 0.056 13.3 0.2 2.4 2 1 0 2 2 2 1 RsgA GTPase ArsA_ATPase PF02374.15 EQB60204.1 - 0.0066 15.7 0.4 2.3 7.3 0.0 2.5 3 0 0 3 3 3 2 Anion-transporting ATPase AAA PF00004.29 EQB60204.1 - 0.0081 16.6 0.0 0.52 10.7 0.0 2.5 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 EQB60204.1 - 0.024 14.6 0.6 1.3 8.9 0.0 2.8 1 1 1 3 3 3 0 AAA domain VirC1 PF07015.11 EQB60204.1 - 0.027 13.8 0.1 0.074 12.3 0.1 1.7 1 1 0 1 1 1 0 VirC1 protein AAA_30 PF13604.6 EQB60204.1 - 0.035 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EQB60204.1 - 0.039 13.6 5.1 0.16 11.7 0.2 2.6 1 1 1 2 2 2 0 AAA ATPase domain Pyr_redox_2 PF07992.14 EQB60204.1 - 0.098 11.9 0.1 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.6 EQB60204.1 - 0.1 12.9 0.1 0.4 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EQB60204.1 - 0.12 12.6 0.0 0.5 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EQB60204.1 - 0.16 11.8 1.9 3.4 7.6 0.0 2.6 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HP0268 PF18618.1 EQB60204.1 - 0.4 11.1 6.9 0.68 10.4 3.2 3.0 2 1 1 4 4 4 0 HP0268 Pkinase PF00069.25 EQB60205.1 - 3.4e-71 239.7 0.3 3.9e-71 239.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60205.1 - 5.4e-29 101.3 0.0 6.6e-29 101.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EQB60205.1 - 5e-07 29.0 0.8 4.7e-06 25.8 0.8 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EQB60205.1 - 2.5e-06 27.1 0.3 2.2e-05 23.9 0.1 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EQB60205.1 - 3.7e-05 23.2 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EQB60205.1 - 0.0018 17.4 2.4 0.0052 15.9 2.4 1.8 1 1 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EQB60205.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EQB60205.1 - 0.18 11.4 0.9 1.3 8.6 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 EQB60206.1 - 1.4e-48 164.6 0.0 1.6e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB60206.1 - 1.1e-23 83.8 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB60206.1 - 2.8e-08 33.4 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EQB60206.1 - 0.031 13.8 0.0 0.15 11.6 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 EQB60206.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 EQB60206.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EQB60206.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Cofilin_ADF PF00241.20 EQB60207.1 - 3.3e-16 59.2 0.2 4.1e-16 58.9 0.2 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pox_MCEL PF03291.16 EQB60208.1 - 2.1e-39 135.6 11.1 2.5e-39 135.3 11.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EQB60208.1 - 4.5e-10 40.1 0.0 7.7e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EQB60208.1 - 7.2e-10 38.9 0.1 1.3e-09 38.0 0.1 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EQB60208.1 - 9e-10 39.2 0.0 1.5e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EQB60208.1 - 1.2e-09 38.2 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EQB60208.1 - 3.2e-09 37.3 0.0 5.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EQB60208.1 - 0.0002 21.1 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.17 EQB60208.1 - 0.00022 20.5 0.0 0.00062 19.0 0.0 1.7 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MetW PF07021.12 EQB60208.1 - 0.017 14.7 0.9 0.03 13.9 0.1 2.0 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW MTS PF05175.14 EQB60208.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Ribosom_S12_S23 PF00164.25 EQB60209.1 - 1.4e-40 137.4 0.9 1.9e-40 137.0 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 VWA_2 PF13519.6 EQB60210.1 - 8.9e-06 26.3 0.0 2.1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EQB60210.1 - 0.025 14.4 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Ssl1-like DUF2206 PF09971.9 EQB60210.1 - 0.037 12.8 0.6 0.051 12.3 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Cadherin_3 PF16184.5 EQB60210.1 - 0.088 12.8 0.6 0.61 10.1 0.1 2.4 3 0 0 3 3 3 0 Cadherin-like Helicase_C PF00271.31 EQB60212.1 - 4.1e-24 85.1 0.5 9e-24 84.0 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EQB60212.1 - 0.00012 21.4 0.1 0.00013 21.3 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DNA_pol_E_B PF04042.16 EQB60213.1 - 2.5e-11 43.3 0.2 3.5e-11 42.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ribosomal_L23 PF00276.20 EQB60215.1 - 4.1e-13 49.5 4.2 8.3e-13 48.5 4.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Pyrophosphatase PF00719.19 EQB60216.1 - 2.5e-23 82.7 0.0 3.2e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-C2H2_2 PF12756.7 EQB60217.1 - 0.0047 17.2 0.1 0.0047 17.2 0.1 3.6 2 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EQB60217.1 - 0.027 14.9 0.5 0.027 14.9 0.5 3.9 5 0 0 5 5 5 0 Zinc-finger of C2H2 type CMV_1a_C PF12503.8 EQB60217.1 - 0.1 12.6 0.6 0.28 11.2 0.6 1.8 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein C terminal zf-C2H2 PF00096.26 EQB60217.1 - 0.19 12.3 0.4 0.19 12.3 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EQB60217.1 - 0.21 12.5 0.2 0.21 12.5 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EQB60217.1 - 0.42 10.9 0.3 0.42 10.9 0.3 3.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding OTT_1508_deam PF14441.6 EQB60217.1 - 1.7 8.7 5.7 5.7 7.0 0.3 2.9 2 1 1 3 3 3 0 OTT_1508-like deaminase Kinesin PF00225.23 EQB60218.1 - 1.3e-77 261.0 15.9 3.9e-49 167.4 6.1 2.0 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EQB60218.1 - 6.3e-25 87.9 2.1 1.5e-24 86.7 2.1 1.6 1 0 0 1 1 1 1 Microtubule binding Peptidase_M24 PF00557.24 EQB60219.1 - 2e-30 106.0 0.1 2.5e-30 105.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 MS_channel PF00924.18 EQB60220.1 - 9.5e-13 48.2 2.3 2.3e-12 46.9 2.3 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel HIT PF01230.23 EQB60221.1 - 3.6e-17 62.9 0.6 5.9e-17 62.2 0.1 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EQB60221.1 - 0.00071 20.0 0.2 0.0014 19.1 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding JIP_LZII PF16471.5 EQB60221.1 - 0.0077 16.4 0.2 0.014 15.6 0.2 1.3 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II CwfJ_C_1 PF04677.15 EQB60221.1 - 0.015 15.1 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 HECT_2 PF09814.9 EQB60222.1 - 2.8e-09 36.3 1.6 5.7e-09 35.3 1.6 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding CEP209_CC5 PF16574.5 EQB60223.1 - 0.021 15.0 2.2 0.021 15.0 2.2 2.5 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 HMG_CoA_synt_N PF01154.17 EQB60224.1 - 2.4e-47 161.0 1.0 3.5e-47 160.5 1.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EQB60224.1 - 1.7e-21 77.1 8.1 2.2e-14 53.8 0.3 2.2 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 EQB60224.1 - 4.9e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal UDG PF03167.19 EQB60225.1 - 2.7e-24 85.9 0.0 4.2e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF3452 PF11934.8 EQB60226.1 - 0.018 14.6 5.5 0.047 13.3 5.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF5365 PF17326.2 EQB60226.1 - 0.039 14.4 1.5 0.039 14.4 1.5 2.3 1 1 2 3 3 3 0 Family of unknown function (DUF5365) Scm3 PF10384.9 EQB60226.1 - 0.043 13.6 4.2 4.1 7.2 0.2 2.9 1 1 1 2 2 2 0 Centromere protein Scm3 His_kinase PF06580.13 EQB60227.1 - 0.031 14.6 0.9 0.065 13.6 0.7 1.7 1 1 0 1 1 1 0 Histidine kinase SMC_N PF02463.19 EQB60228.1 - 1.2e-07 31.4 1.6 1.7e-07 30.9 1.6 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EQB60228.1 - 0.00029 21.0 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EQB60228.1 - 0.028 14.9 0.5 0.18 12.3 0.5 2.1 1 1 0 1 1 1 0 ABC transporter DUF5615 PF18480.1 EQB60228.1 - 0.1 12.4 0.1 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) RAMPs PF03787.15 EQB60228.1 - 1.8 8.5 4.8 2 8.4 4.8 1.3 1 1 0 1 1 1 0 RAMP superfamily SMC_N PF02463.19 EQB60229.1 - 7.9e-08 32.0 1.1 1.2e-07 31.4 1.1 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EQB60229.1 - 0.00026 21.1 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EQB60229.1 - 0.0016 18.3 17.0 0.0033 17.2 17.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EQB60229.1 - 0.057 13.9 0.3 0.18 12.3 0.3 2.0 1 1 0 1 1 1 0 ABC transporter DUF5615 PF18480.1 EQB60229.1 - 0.088 12.6 0.1 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) RAMPs PF03787.15 EQB60229.1 - 1 9.4 4.1 1.2 9.2 4.1 1.3 1 1 0 1 1 1 0 RAMP superfamily Ribosomal_S27e PF01667.17 EQB60230.1 - 2.6e-05 23.8 1.1 3.7e-05 23.4 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 Cpn60_TCP1 PF00118.24 EQB60232.1 - 4.8e-25 88.2 0.1 1e-24 87.1 0.1 1.5 1 1 1 2 2 2 1 TCP-1/cpn60 chaperonin family UCH PF00443.29 EQB60233.1 - 9.6e-17 61.3 6.0 1.5e-16 60.6 6.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EQB60233.1 - 7.5e-07 29.0 5.0 2.2e-06 27.5 5.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IBR PF01485.21 EQB60233.1 - 0.66 10.3 7.5 0.4 10.9 5.2 1.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain LRR_8 PF13855.6 EQB60234.1 - 2e-26 91.5 58.7 1.7e-13 50.1 2.2 8.5 5 2 4 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 EQB60234.1 - 9.1e-18 64.1 80.6 6.4e-06 26.4 4.5 10.0 4 1 10 14 14 14 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB60234.1 - 2.6 8.9 58.0 4.8 8.1 0.1 12.1 12 1 0 12 12 12 0 Leucine Rich Repeat NAD_Gly3P_dh_C PF07479.14 EQB60235.1 - 2e-39 135.1 0.1 3.2e-39 134.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EQB60235.1 - 1e-20 74.3 0.1 1.6e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EQB60235.1 - 0.0048 16.5 0.2 0.17 11.5 0.2 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA PRP8_domainIV PF12134.8 EQB60236.1 - 0.0014 18.4 3.6 0.12 12.0 0.1 3.0 2 1 1 3 3 3 2 PRP8 domain IV core MqsA_antitoxin PF15731.5 EQB60236.1 - 0.98 9.5 4.4 0.3 11.2 0.8 1.9 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA PRP8_domainIV PF12134.8 EQB60237.1 - 0.00073 19.2 2.0 0.12 12.0 0.1 2.7 1 1 1 2 2 2 2 PRP8 domain IV core PROCN PF08083.11 EQB60239.1 - 3.6e-48 164.3 35.3 7.2e-25 87.5 9.6 6.5 5 1 0 5 5 5 5 PROCN (NUC071) domain U5_2-snRNA_bdg PF10597.9 EQB60239.1 - 3.4e-28 98.4 0.1 3.4e-28 98.4 0.1 2.1 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EQB60239.1 - 5.2e-16 58.8 0.5 2e-15 56.9 0.5 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PRO8NT PF08082.11 EQB60239.1 - 0.0064 16.4 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain PROCN PF08083.11 EQB60240.1 - 3.3e-45 154.5 28.2 3.5e-25 88.6 10.0 4.4 3 1 0 3 3 3 3 PROCN (NUC071) domain PRO8NT PF08082.11 EQB60240.1 - 8.8e-15 54.9 0.0 8.4e-14 51.8 0.0 2.4 1 1 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain eIF-6 PF01912.18 EQB60242.1 - 3.7e-68 228.8 2.1 4.4e-68 228.6 2.1 1.1 1 0 0 1 1 1 1 eIF-6 family Glucosamine_iso PF01182.20 EQB60246.1 - 2e-42 145.6 0.0 6.5e-23 81.8 0.0 2.1 1 1 1 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Lactamase_B_6 PF16661.5 EQB60246.1 - 0.005 16.3 0.0 2 7.8 0.0 2.5 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily domain AbiJ_NTD3 PF18860.1 EQB60246.1 - 0.016 14.7 0.1 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AbiJ N-terminal domain 3 NOG1 PF06858.14 EQB60246.1 - 0.021 14.6 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) GST_C PF00043.25 EQB60246.1 - 0.024 14.9 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3677 PF12432.8 EQB60246.1 - 0.06 13.7 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) DUF2312 PF10073.9 EQB60247.1 - 2.6 7.8 7.8 1.3 8.7 3.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) ABC_tran PF00005.27 EQB60248.1 - 2.2e-26 93.0 0.0 5.2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EQB60248.1 - 4.1e-10 39.8 21.0 6.9e-10 39.0 21.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EQB60248.1 - 0.00025 20.6 5.6 0.14 11.6 0.7 2.5 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EQB60248.1 - 0.0012 18.7 0.3 0.0012 18.7 0.3 2.8 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 EQB60248.1 - 0.0074 16.1 0.2 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_29 PF13555.6 EQB60248.1 - 0.011 15.4 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EQB60248.1 - 0.023 15.0 0.1 0.092 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EQB60248.1 - 0.052 12.7 0.2 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Brix PF04427.18 EQB60249.1 - 5.8e-08 33.1 0.3 6.8e-08 32.8 0.3 1.2 1 0 0 1 1 1 1 Brix domain DUF3316 PF11777.8 EQB60251.1 - 0.037 14.1 0.6 0.062 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) Peptidase_M48 PF01435.18 EQB60252.1 - 1.3e-19 70.8 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EQB60252.1 - 0.1 11.7 8.5 0.087 12.0 4.9 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 Na_H_antiporter PF03553.14 EQB60252.1 - 0.51 9.5 8.8 0.59 9.3 1.3 2.5 1 1 1 2 2 2 0 Na+/H+ antiporter family K1 PF02960.14 EQB60252.1 - 0.89 9.7 9.1 0.097 12.8 1.0 2.7 2 1 0 2 2 2 0 K1 glycoprotein MCM_OB PF17207.3 EQB60254.1 - 2.9e-13 49.8 0.1 4.6e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 EQB60254.1 - 1e-11 45.3 1.0 2.1e-11 44.3 1.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Zn-ribbon_8 PF09723.10 EQB60254.1 - 0.096 12.8 1.0 0.23 11.6 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain UPF0515 PF15135.6 EQB60254.1 - 2.9 7.2 5.5 0.53 9.6 1.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 Ycf15 PF10705.9 EQB60256.1 - 3.2 8.0 6.7 4.8 7.4 0.4 3.2 2 1 1 3 3 3 0 Chloroplast protein precursor Ycf15 putative XPA_C PF05181.12 EQB60257.1 - 2.3e-20 72.3 0.9 3.8e-20 71.6 0.9 1.4 1 0 0 1 1 1 1 XPA protein C-terminus HisK_sensor PF18698.1 EQB60257.1 - 0.048 14.1 2.4 0.052 13.9 1.4 1.5 2 0 0 2 2 2 0 Histidine kinase sensor domain XPA_N PF01286.18 EQB60257.1 - 0.05 13.6 2.6 0.14 12.3 2.6 1.8 1 0 0 1 1 1 0 XPA protein N-terminal SAWADEE PF16719.5 EQB60257.1 - 0.18 11.8 5.3 2.7 8.0 5.3 2.1 1 1 0 1 1 1 0 SAWADEE domain UFD1 PF03152.14 EQB60258.1 - 2.5e-46 157.3 0.1 3.5e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UFD1 PF03152.14 EQB60259.1 - 1.2e-19 70.4 0.1 1.8e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CK_II_beta PF01214.18 EQB60260.1 - 3.6e-47 160.5 1.3 4.6e-47 160.2 1.3 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit NUMOD1 PF07453.13 EQB60262.1 - 0.0031 17.7 0.8 0.2 12.0 0.1 2.7 2 0 0 2 2 2 2 NUMOD1 domain TraF PF13728.6 EQB60262.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Guanylate_kin PF00625.21 EQB60264.1 - 1.7e-20 73.5 2.9 4.9e-20 72.0 2.9 1.7 1 1 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EQB60264.1 - 6.8e-07 29.9 0.3 2e-06 28.4 0.3 1.8 1 1 0 1 1 1 1 AAA domain zf-CCCH PF00642.24 EQB60264.1 - 0.00017 21.4 12.1 0.00063 19.6 1.4 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EQB60264.1 - 0.0002 21.5 5.2 0.00038 20.6 5.2 1.5 1 0 0 1 1 1 1 Zinc-finger containing family AAA_23 PF13476.6 EQB60264.1 - 0.00021 21.9 1.1 0.001 19.6 1.1 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EQB60264.1 - 0.00044 20.0 0.7 0.44 10.2 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase NACHT PF05729.12 EQB60264.1 - 0.0018 18.2 1.9 0.2 11.6 0.0 2.6 2 1 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 EQB60264.1 - 0.0018 18.3 0.1 0.0041 17.2 0.0 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EQB60264.1 - 0.0023 18.2 0.0 0.0051 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EQB60264.1 - 0.0025 17.7 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_29 PF13555.6 EQB60264.1 - 0.0045 16.7 0.3 0.008 15.9 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EQB60264.1 - 0.0046 17.4 0.0 0.0094 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EQB60264.1 - 0.006 16.2 0.4 0.016 14.8 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EQB60264.1 - 0.0062 17.1 0.0 0.0099 16.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter dNK PF01712.19 EQB60264.1 - 0.0076 16.1 1.9 0.23 11.3 0.5 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_7 PF12775.7 EQB60264.1 - 0.0079 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region zf-CCCH_4 PF18044.1 EQB60264.1 - 0.0086 15.9 3.0 0.0086 15.9 3.0 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EQB60264.1 - 0.014 15.4 4.3 0.014 15.4 4.3 3.3 2 1 0 2 2 2 0 Zinc finger domain AAA_16 PF13191.6 EQB60264.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EQB60264.1 - 0.015 15.4 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EQB60264.1 - 0.017 15.5 0.1 0.5 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EQB60264.1 - 0.017 15.4 0.1 0.036 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EQB60264.1 - 0.022 15.1 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EQB60264.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EQB60264.1 - 0.032 13.3 0.3 0.05 12.6 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EQB60264.1 - 0.035 14.0 0.2 0.081 12.8 0.0 1.6 2 0 0 2 2 1 0 RsgA GTPase zf-CCCH_2 PF14608.6 EQB60264.1 - 0.038 14.5 15.0 0.41 11.2 4.6 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AAA_28 PF13521.6 EQB60264.1 - 0.042 14.1 0.6 0.2 11.9 0.4 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EQB60264.1 - 0.064 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MobB PF03205.14 EQB60264.1 - 0.065 13.1 0.3 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 EQB60264.1 - 0.072 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EQB60264.1 - 0.084 12.0 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 EQB60264.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 EQB60264.1 - 0.3 10.8 4.7 1 9.1 4.7 1.9 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 EQB60264.1 - 0.33 11.0 5.3 0.4 10.7 0.1 2.4 1 1 0 2 2 2 0 AAA domain Torus PF16131.5 EQB60264.1 - 1.6 9.4 6.9 0.85 10.3 3.3 2.0 1 1 1 2 2 2 0 Torus domain Imm27 PF15590.6 EQB60268.1 - 0.027 14.2 0.2 0.083 12.7 0.2 1.8 1 0 0 1 1 1 0 Immunity protein 27 Ribosomal_S7 PF00177.21 EQB60269.1 - 6.8e-35 119.9 0.7 8.3e-35 119.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Pox_H7 PF04787.12 EQB60269.1 - 0.063 13.8 0.1 0.79 10.2 0.0 2.2 2 0 0 2 2 2 0 Late protein H7 Cpn60_TCP1 PF00118.24 EQB60271.1 - 5.8e-104 348.4 6.3 4e-103 345.7 6.3 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DHFR_1 PF00186.19 EQB60271.1 - 0.014 15.1 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 Dihydrofolate reductase zf-CpG_bind_C PF12269.8 EQB60271.1 - 0.1 12.4 0.3 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Homeodomain PF00046.29 EQB60272.1 - 2.1e-17 62.7 1.7 4.3e-17 61.7 1.7 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EQB60272.1 - 0.00022 21.1 0.4 0.00044 20.1 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 EQB60272.1 - 0.028 14.2 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain MerR_1 PF13411.6 EQB60272.1 - 0.047 13.8 0.8 0.071 13.2 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein RVT_1 PF00078.27 EQB60273.1 - 1.5e-08 34.5 0.2 2.2e-08 33.9 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GDPD PF03009.17 EQB60275.1 - 1.1e-17 64.6 0.0 1.7e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RNA_pol_Rpb4 PF03874.16 EQB60276.1 - 1.9e-10 41.2 1.8 3e-10 40.5 1.8 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Septin PF00735.18 EQB60277.1 - 2.2e-49 168.2 11.3 2.7e-49 167.9 8.7 2.2 1 1 0 1 1 1 1 Septin Dynamin_N PF00350.23 EQB60277.1 - 0.0015 18.6 1.2 0.0071 16.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 EQB60277.1 - 0.0036 17.0 0.5 0.011 15.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EQB60277.1 - 0.0087 16.1 0.5 0.026 14.6 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EQB60277.1 - 0.011 16.3 0.2 0.036 14.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EQB60277.1 - 0.044 13.7 3.8 0.39 10.6 0.1 2.9 3 1 0 3 3 3 0 RsgA GTPase Arm PF00514.23 EQB60278.1 - 3.6e-37 125.3 4.8 3.1e-08 33.4 0.0 7.9 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 EQB60278.1 - 1.2e-07 31.2 1.9 3.1e-07 29.8 1.2 2.2 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 EQB60278.1 - 1.2e-07 32.1 0.1 0.0024 18.4 0.0 3.9 3 1 2 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EQB60278.1 - 9.1e-06 26.0 0.0 0.67 10.4 0.0 3.7 2 2 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EQB60278.1 - 0.0009 19.3 0.1 0.99 9.8 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat SYCP2_ARLD PF18581.1 EQB60278.1 - 0.077 13.0 0.3 1.2 9.1 0.1 2.8 1 1 2 3 3 3 0 Synaptonemal complex 2 armadillo-repeat-like domain Aminotran_5 PF00266.19 EQB60279.1 - 3e-90 302.9 0.0 3.5e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EQB60279.1 - 6.6e-06 25.6 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EQB60279.1 - 2.1e-05 24.0 0.1 4.5e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EQB60279.1 - 0.00016 20.6 0.0 0.00025 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EQB60279.1 - 0.054 12.0 0.1 0.079 11.5 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Transketolase_C PF02780.20 EQB60279.1 - 0.08 12.8 0.4 0.22 11.4 0.1 2.0 3 0 0 3 3 3 0 Transketolase, C-terminal domain EF-hand_8 PF13833.6 EQB60280.1 - 0.0012 18.6 0.4 0.42 10.5 0.1 3.3 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EQB60280.1 - 0.0038 17.0 0.5 17 5.7 0.0 4.2 4 1 1 5 5 5 1 EF-hand domain RST PF12174.8 EQB60280.1 - 0.0039 17.1 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain Frankia_peptide PF14407.6 EQB60280.1 - 0.017 15.1 0.1 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PuR_N PF09182.10 EQB60280.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal RNA_pol_Rpb4 PF03874.16 EQB60280.1 - 0.035 14.4 1.5 0.44 10.9 1.5 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb4 EF-hand_7 PF13499.6 EQB60280.1 - 0.1 13.0 1.5 2.6 8.6 0.4 2.6 1 1 1 2 2 2 0 EF-hand domain pair DUF2757 PF10955.8 EQB60280.1 - 0.23 11.7 2.4 1.1 9.6 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2757) EF-hand_1 PF00036.32 EQB60280.1 - 0.56 9.9 3.8 16 5.3 0.1 4.1 5 0 0 5 5 5 0 EF hand Maf1 PF09174.10 EQB60281.1 - 2.6e-18 66.8 8.6 5e-18 65.9 8.6 1.4 1 1 0 1 1 1 1 Maf1 regulator PAXNEB PF05625.11 EQB60281.1 - 0.098 11.8 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 PAXNEB protein Nsp1_C PF05064.13 EQB60283.1 - 0.0027 17.5 5.4 0.0027 17.5 5.4 2.7 3 1 0 3 3 3 1 Nsp1-like C-terminal region DivIVA PF05103.13 EQB60283.1 - 0.019 15.1 1.3 0.019 15.1 1.3 3.1 3 1 1 4 4 4 0 DivIVA protein Elf1 PF05129.13 EQB60283.1 - 0.032 14.3 0.4 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like CHCH PF06747.13 EQB60283.1 - 0.21 11.7 1.4 3.6 7.8 0.6 2.9 1 1 1 2 2 2 0 CHCH domain MAP70 PF07058.11 EQB60283.1 - 0.41 9.3 11.8 0.65 8.7 11.8 1.4 1 0 0 1 1 1 0 Microtubule-associated protein 70 PurS PF02700.14 EQB60285.1 - 0.11 12.7 1.0 0.32 11.2 1.0 1.9 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF5582 PF17819.1 EQB60286.1 - 0.022 15.2 2.2 0.032 14.7 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) RNase_T PF00929.24 EQB60287.1 - 1.6e-06 28.8 0.0 4.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Corona_5a PF06336.11 EQB60287.1 - 0.099 12.6 0.3 0.23 11.5 0.3 1.6 1 0 0 1 1 1 0 Coronavirus 5a protein Ras PF00071.22 EQB60290.1 - 0.0079 15.8 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Ras family MeaB PF03308.16 EQB60290.1 - 0.01 14.8 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MnmE_helical PF12631.7 EQB60290.1 - 0.094 12.9 0.1 0.097 12.8 0.1 1.1 1 0 0 1 1 1 0 MnmE helical domain Ribonuc_red_lgC PF02867.15 EQB60291.1 - 4.9e-179 596.2 0.0 5.7e-179 596.0 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EQB60291.1 - 2.7e-07 30.5 0.0 6.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain LRR_8 PF13855.6 EQB60292.1 - 2.4e-11 43.2 20.9 1.4e-08 34.4 1.0 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EQB60292.1 - 1.8e-06 28.2 28.1 9e-05 22.8 4.8 4.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB60292.1 - 0.79 10.5 20.2 11 7.0 0.9 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat TraF PF13728.6 EQB60293.1 - 0.0049 16.7 1.2 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 F plasmid transfer operon protein BsuBI_PstI_RE PF06616.11 EQB60293.1 - 0.017 14.4 0.4 0.03 13.6 0.4 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain HSDR_N_2 PF13588.6 EQB60293.1 - 0.066 13.2 2.4 0.12 12.4 1.7 1.8 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Glutaredoxin PF00462.24 EQB60293.1 - 0.1 12.8 0.2 0.6 10.4 0.4 2.2 2 0 0 2 2 2 0 Glutaredoxin DM13 PF10517.9 EQB60293.1 - 0.13 12.9 0.2 0.47 11.1 0.3 1.8 2 0 0 2 2 2 0 Electron transfer DM13 PepSY_like PF11396.8 EQB60293.1 - 0.29 11.7 5.9 7.7 7.1 0.0 2.5 2 1 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like LRR_8 PF13855.6 EQB60294.1 - 2.8e-20 71.8 54.3 8.1e-08 31.9 10.1 4.5 2 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EQB60294.1 - 2.5e-16 59.5 60.7 7.1e-07 29.5 6.6 6.3 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60294.1 - 4.3e-06 26.3 23.1 0.0035 16.9 3.0 3.0 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EQB60294.1 - 0.0043 17.4 51.9 0.52 11.1 1.5 9.6 9 1 0 9 9 9 4 Leucine Rich Repeat HECT PF00632.25 EQB60296.1 - 3.5e-38 131.8 1.3 4.1e-38 131.6 1.3 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Choline_transpo PF04515.12 EQB60297.1 - 6.1e-23 81.5 22.1 1.3e-22 80.5 22.2 1.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter GPDPase_memb PF10110.9 EQB60297.1 - 0.0072 15.2 24.1 0.0068 15.2 15.6 2.1 1 1 1 2 2 2 1 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF334 PF03904.13 EQB60297.1 - 0.014 15.0 2.4 0.02 14.5 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF1761 PF08570.10 EQB60297.1 - 0.067 13.5 5.8 7.1 6.9 4.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1761) DUF3844 PF12955.7 EQB60297.1 - 0.25 11.5 0.8 0.64 10.2 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) TLC PF03219.14 EQB60298.1 - 1.1e-32 113.5 11.1 1.3e-32 113.2 11.1 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter LapA_dom PF06305.11 EQB60298.1 - 0.31 10.9 3.5 0.33 10.8 0.3 2.8 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RNase_PH PF01138.21 EQB60299.1 - 7.7e-07 29.7 0.0 1.4e-06 28.8 0.0 1.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Elf1 PF05129.13 EQB60300.1 - 1.3e-22 79.6 6.9 1.8e-22 79.2 6.9 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf_C2H2_10 PF18414.1 EQB60300.1 - 0.034 13.7 0.5 0.076 12.6 0.5 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger Lar_restr_allev PF14354.6 EQB60300.1 - 0.04 14.3 4.1 0.066 13.6 4.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-HC5HC2H PF13771.6 EQB60300.1 - 0.12 12.7 8.0 0.34 11.2 8.0 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF678 PF05077.12 EQB60300.1 - 0.13 12.4 3.7 0.17 12.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Cys_rich_KTR PF14205.6 EQB60300.1 - 2.2 8.2 9.7 0.81 9.5 5.1 2.3 2 1 0 2 2 2 0 Cysteine-rich KTR TPR_2 PF07719.17 EQB60301.1 - 0.0004 20.3 9.2 0.039 14.1 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EQB60301.1 - 0.005 17.0 1.1 0.005 17.0 1.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat SPOB_a PF14689.6 EQB60301.1 - 0.022 14.5 1.7 0.33 10.7 0.1 3.3 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF3149 PF11346.8 EQB60301.1 - 0.026 14.1 0.6 0.21 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) TPR_12 PF13424.6 EQB60301.1 - 0.13 12.6 4.5 0.62 10.4 2.2 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EQB60301.1 - 0.34 11.4 6.6 0.63 10.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4025 PF13217.6 EQB60301.1 - 0.45 10.4 1.6 0.93 9.4 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4025) TPR_1 PF00515.28 EQB60301.1 - 2.3 8.2 16.8 4.6 7.2 1.3 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Glutaredoxin PF00462.24 EQB60303.1 - 2.3e-14 53.3 0.4 3.3e-14 52.8 0.4 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EQB60303.1 - 0.0034 17.8 0.0 0.0041 17.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 EQB60303.1 - 0.0074 16.7 0.2 0.0092 16.4 0.2 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EQB60303.1 - 0.016 15.6 0.5 0.02 15.4 0.5 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain CopK PF11525.8 EQB60304.1 - 0.14 11.8 2.1 1.3 8.7 0.7 2.2 1 1 1 2 2 2 0 Copper resistance protein K PCI PF01399.27 EQB60305.1 - 5.6e-12 46.1 2.2 1.4e-11 44.8 2.2 1.7 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EQB60305.1 - 0.18 11.8 7.7 0.13 12.2 4.1 2.5 2 1 0 2 2 2 0 CSN8/PSMD8/EIF3K family Arf PF00025.21 EQB60306.1 - 0.00045 19.7 0.2 0.00064 19.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EQB60306.1 - 0.047 13.1 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EQB60306.1 - 0.18 12.0 0.2 0.53 10.5 0.0 1.6 1 1 1 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 EQB60307.1 - 4.9e-11 42.7 0.4 8.8e-11 41.8 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EQB60307.1 - 1.3e-09 38.3 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 EQB60307.1 - 4.9e-07 30.0 0.0 9.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EQB60307.1 - 0.0018 18.7 0.3 0.0079 16.6 0.2 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EQB60307.1 - 0.0087 15.9 1.2 0.013 15.3 0.3 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit IFN-gamma PF00714.17 EQB60307.1 - 0.23 11.3 3.6 2.6 7.9 0.2 2.4 1 1 1 2 2 2 0 Interferon gamma Glyco_hydro_19 PF00182.19 EQB60308.1 - 1.8e-23 83.7 1.5 2.4e-20 73.4 1.5 2.7 1 1 0 1 1 1 1 Chitinase class I CBM_19 PF03427.13 EQB60309.1 - 0.58 10.2 4.3 1.4 9.0 4.3 1.7 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) adh_short PF00106.25 EQB60310.1 - 8.3e-15 54.8 1.3 1.4e-12 47.5 1.3 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EQB60310.1 - 7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EQB60310.1 - 0.0032 17.4 0.2 0.7 9.8 0.2 2.3 1 1 0 2 2 2 2 KR domain DUF2977 PF11192.8 EQB60310.1 - 0.04 14.1 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2977) Rep_fac-A_C PF08646.10 EQB60311.1 - 3.3e-43 146.9 10.8 3.3e-43 146.9 10.8 3.3 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EQB60311.1 - 1.6e-23 82.5 3.7 3.6e-23 81.3 2.3 2.3 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EQB60311.1 - 2.6e-17 62.6 7.7 2.8e-11 43.3 0.4 4.2 3 1 2 5 5 5 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 EQB60311.1 - 9.5e-14 51.2 0.0 4.5e-13 49.1 0.0 2.2 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF4539 PF15072.6 EQB60311.1 - 4.9e-06 26.5 0.1 0.02 14.9 0.1 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 EQB60311.1 - 0.00049 19.9 8.3 0.77 9.4 5.8 3.3 2 1 0 2 2 2 2 Cell division control protein 24, OB domain 3 RMI1_C PF16099.5 EQB60311.1 - 0.0017 18.2 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 Recq-mediated genome instability protein 1, C-terminal OB-fold DUF223 PF02721.14 EQB60311.1 - 0.0062 16.8 0.7 0.0062 16.8 0.7 3.4 3 1 1 4 4 4 1 Domain of unknown function DUF223 Cpn60_TCP1 PF00118.24 EQB60312.1 - 6.2e-66 223.0 0.0 6.9e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 EQB60313.1 - 1.1e-47 162.8 0.4 1.3e-47 162.6 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DpnI_C PF17726.1 EQB60313.1 - 0.058 13.5 1.2 0.21 11.7 0.4 2.3 1 1 1 2 2 2 0 Dam-replacing HTH domain NFACT-C PF11923.8 EQB60314.1 - 5e-17 61.7 0.2 1.2e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EQB60314.1 - 4e-05 24.2 0.0 7.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain DDE_Tnp_1_7 PF13843.6 EQB60315.1 - 1.4e-14 54.2 0.8 3.1e-14 53.0 0.8 1.6 1 1 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.27 EQB60316.1 - 4.2e-05 23.2 0.1 0.0066 16.0 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EQB60317.1 - 2.8e-05 24.1 1.7 0.022 14.8 0.1 4.4 3 1 1 4 4 4 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EQB60317.1 - 0.033 14.5 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Pro_racemase PF05544.11 EQB60317.1 - 0.048 12.7 0.1 0.23 10.5 0.1 1.9 2 0 0 2 2 2 0 Proline racemase BsuBI_PstI_RE PF06616.11 EQB60318.1 - 0.017 14.4 0.5 0.062 12.6 0.3 2.0 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease domain Pkinase PF00069.25 EQB60319.1 - 8.4e-40 136.8 1.7 1.1e-39 136.5 1.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60319.1 - 4.4e-20 72.0 0.1 6.1e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S11 PF00411.19 EQB60320.1 - 1e-37 128.9 2.9 1.3e-37 128.5 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 SpoIIID PF12116.8 EQB60321.1 - 0.01 15.9 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein D PMBR PF09373.10 EQB60321.1 - 0.031 14.4 0.3 0.063 13.5 0.3 1.5 1 0 0 1 1 1 0 Pseudomurein-binding repeat Pyr_redox_2 PF07992.14 EQB60323.1 - 1.2e-40 139.6 0.4 4.1e-40 137.9 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EQB60323.1 - 2.6e-21 76.2 2.3 2.6e-21 76.2 2.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EQB60323.1 - 9.7e-08 32.5 1.9 3.7e-07 30.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EQB60323.1 - 1.6e-05 24.2 0.3 0.0026 16.9 0.9 2.9 4 0 0 4 4 4 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EQB60323.1 - 0.01 16.3 0.0 0.043 14.2 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF2981 PF11200.8 EQB60323.1 - 2.9 7.6 4.7 3.9 7.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF5089 PF17002.5 EQB60324.1 - 4.5e-52 176.7 19.6 4.5e-52 176.7 19.6 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) Chrome_Resist PF09828.9 EQB60324.1 - 0.065 13.7 3.0 0.32 11.5 0.1 2.2 2 0 0 2 2 2 0 Chromate resistance exported protein Ndc1_Nup PF09531.10 EQB60324.1 - 0.56 8.8 4.6 0.57 8.8 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 EQB60324.1 - 5.4 7.0 10.6 1.6 8.7 7.5 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAD PF05557.13 EQB60326.1 - 6.5e-15 54.6 0.7 6.7e-15 54.5 0.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein HALZ PF02183.18 EQB60326.1 - 0.11 12.7 0.4 0.11 12.7 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Baculo_LEF-10 PF07206.11 EQB60326.1 - 0.14 12.4 1.2 0.25 11.5 1.2 1.5 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) Ribosomal_L35Ae PF01247.18 EQB60327.1 - 1.8e-17 63.3 2.0 1.8e-17 63.3 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L35Ae RimM PF01782.18 EQB60327.1 - 0.049 13.8 0.5 0.41 10.9 0.2 2.3 2 0 0 2 2 2 0 RimM N-terminal domain Trehalase PF01204.18 EQB60328.1 - 3.6e-51 174.6 8.0 7.1e-50 170.3 8.0 2.1 1 1 0 1 1 1 1 Trehalase DUF2418 PF10332.9 EQB60328.1 - 0.065 13.8 0.5 0.24 12.0 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) DUF327 PF03885.13 EQB60328.1 - 0.27 11.2 12.6 0.1 12.5 9.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) zf-C2H2 PF00096.26 EQB60330.1 - 3e-05 24.2 12.8 0.048 14.1 1.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EQB60330.1 - 0.0002 21.9 7.6 0.0024 18.6 1.0 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EQB60330.1 - 0.00042 20.0 0.3 0.00042 20.0 0.3 3.6 4 0 0 4 4 4 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 EQB60330.1 - 0.0026 18.1 0.7 0.0026 18.1 0.7 4.4 5 0 0 5 5 5 1 Zinc-finger double domain zf-BED PF02892.15 EQB60330.1 - 0.53 10.4 8.4 0.61 10.2 0.4 3.1 3 1 0 3 3 3 0 BED zinc finger Proteasome PF00227.26 EQB60332.1 - 5.2e-26 91.3 0.3 9.3e-26 90.5 0.3 1.3 1 1 0 1 1 1 1 Proteasome subunit HORMA PF02301.18 EQB60333.1 - 2.4e-28 99.2 0.1 2.4e-28 99.2 0.1 2.7 3 0 0 3 3 3 1 HORMA domain PHD PF00628.29 EQB60333.1 - 3.7e-06 26.7 10.3 1.1e-05 25.2 10.3 1.9 1 0 0 1 1 1 1 PHD-finger Penicillinase_R PF03965.16 EQB60333.1 - 0.13 12.6 0.2 0.27 11.6 0.2 1.4 1 0 0 1 1 1 0 Penicillinase repressor RNA_pol_Rpb5_C PF01191.19 EQB60334.1 - 3.8e-30 103.6 0.2 4.7e-30 103.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Enkurin PF13864.6 EQB60334.1 - 0.025 15.0 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 Calmodulin-binding zf-C2H2_jaz PF12171.8 EQB60335.1 - 7.6e-10 38.8 2.1 7.6e-10 38.8 2.1 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EQB60335.1 - 2.6e-06 27.6 1.9 2.6e-06 27.6 1.9 3.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EQB60335.1 - 3.5e-05 24.3 11.1 0.0019 18.9 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EQB60335.1 - 7e-05 23.1 0.3 7e-05 23.1 0.3 2.4 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EQB60335.1 - 0.0048 16.8 0.1 0.0048 16.8 0.1 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 EQB60335.1 - 0.0077 16.6 14.5 0.16 12.5 0.9 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 EQB60335.1 - 0.034 14.3 0.5 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 EQB60335.1 - 0.06 13.3 0.3 0.06 13.3 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 EQB60335.1 - 0.17 12.3 10.8 0.16 12.4 2.8 2.6 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RING_2 PF13639.6 EQB60337.1 - 1.3e-10 41.5 10.6 1.3e-10 41.5 10.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB60337.1 - 5.5e-07 29.3 10.2 1.6e-06 27.9 10.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EQB60337.1 - 2.3e-06 27.8 11.1 7.1e-06 26.2 11.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EQB60337.1 - 3.2e-06 26.9 10.4 3.2e-06 26.9 10.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EQB60337.1 - 1.2e-05 24.9 3.0 1.2e-05 24.9 3.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EQB60337.1 - 5e-05 23.2 4.6 5e-05 23.2 4.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EQB60337.1 - 0.00026 21.1 8.9 0.00026 21.1 8.9 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EQB60337.1 - 0.00027 20.7 7.4 0.00027 20.7 7.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EQB60337.1 - 0.0019 18.2 3.0 0.0037 17.3 3.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EQB60337.1 - 0.013 15.4 11.5 0.063 13.2 11.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 EQB60337.1 - 0.049 13.8 3.6 0.11 12.6 3.6 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_4 PF14447.6 EQB60337.1 - 0.053 13.4 10.0 0.78 9.6 4.6 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-HC5HC2H PF13771.6 EQB60337.1 - 0.2 11.9 6.0 0.43 10.9 6.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 EQB60337.1 - 2.2 8.0 12.3 0.055 13.1 5.5 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EQB60337.1 - 5.2 7.3 10.1 57 4.0 10.1 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain RNA_pol_L_2 PF13656.6 EQB60338.1 - 1.3e-10 40.8 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF5062 PF16691.5 EQB60339.1 - 0.033 14.3 0.1 0.088 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5062) LRR_2 PF07723.13 EQB60341.1 - 0.17 12.6 1.6 0.63 10.8 0.4 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat ArfGap PF01412.18 EQB60342.1 - 1.2e-19 70.5 1.2 2.1e-19 69.7 1.1 1.6 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3868 PF12984.7 EQB60342.1 - 0.0065 16.3 0.3 0.015 15.1 0.1 1.7 2 1 0 2 2 2 1 Domain of unknown function, B. Theta Gene description (DUF3868) YchF-GTPase_C PF06071.13 EQB60343.1 - 6.7e-36 122.4 0.1 6.7e-36 122.4 0.1 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EQB60343.1 - 4.8e-22 78.2 0.7 1.4e-21 76.7 0.2 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EQB60343.1 - 1.2e-07 31.4 0.2 1.2e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF4874 PF16173.5 EQB60343.1 - 0.029 14.1 2.0 0.033 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) MeaB PF03308.16 EQB60343.1 - 0.032 13.2 0.1 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EQB60343.1 - 0.07 13.7 2.1 0.24 12.0 0.0 2.8 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EQB60343.1 - 0.073 13.1 11.6 0.52 10.4 0.0 4.2 2 2 2 4 4 4 0 Dynamin family ABC_tran PF00005.27 EQB60343.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Flg_bb_rod PF00460.20 EQB60343.1 - 1.4 9.0 8.3 3 7.9 8.3 1.5 1 0 0 1 1 1 0 Flagella basal body rod protein FbpA PF05833.11 EQB60344.1 - 8.8e-15 54.4 2.7 4.4e-12 45.5 0.8 2.4 2 1 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) FbpA PF05833.11 EQB60345.1 - 1.8e-12 46.8 1.4 3.2e-12 46.0 1.4 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) MMR_HSR1 PF01926.23 EQB60346.1 - 1.4e-22 79.9 0.0 2.9e-22 78.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EQB60346.1 - 3.9e-08 33.0 0.2 3.9e-08 33.0 0.2 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EQB60346.1 - 3.4e-05 24.0 1.7 0.27 11.3 0.0 3.1 1 1 2 3 3 3 2 Dynamin family MeaB PF03308.16 EQB60346.1 - 0.0091 15.0 0.2 0.055 12.4 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EQB60346.1 - 0.024 15.2 0.0 0.089 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EQB60346.1 - 0.027 13.9 0.6 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EQB60346.1 - 0.036 14.6 0.0 0.1 13.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter YchF-GTPase_C PF06071.13 EQB60347.1 - 5.2e-37 125.9 0.1 1.6e-36 124.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) PNISR PF15996.5 EQB60347.1 - 0.22 11.8 7.8 0.33 11.2 7.8 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Ctr PF04145.15 EQB60347.1 - 2.4 8.8 5.5 5.8 7.5 5.5 1.6 1 1 0 1 1 1 0 Ctr copper transporter family FbpA PF05833.11 EQB60348.1 - 3.7e-10 39.1 0.2 1e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) OMP_b-brl PF13505.6 EQB60348.1 - 0.093 12.9 1.3 0.13 12.4 1.3 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain LRR_8 PF13855.6 EQB60349.1 - 2.3e-28 97.8 48.9 1e-08 34.8 5.9 6.4 2 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EQB60349.1 - 3.3e-24 84.5 68.1 7.8e-07 29.3 1.6 7.5 2 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60349.1 - 1e-05 25.1 28.8 0.00076 19.0 7.4 3.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EQB60349.1 - 7.7e-05 22.7 55.1 2.7 8.9 0.6 11.0 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.6 EQB60349.1 - 0.00028 20.7 48.3 3.5 7.9 0.9 9.9 10 0 0 10 10 10 7 Leucine Rich repeat MutL_C PF08676.11 EQB60353.1 - 1.3e-18 67.2 0.0 6.5e-16 58.4 0.0 3.0 3 0 0 3 3 3 2 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EQB60353.1 - 8.3e-10 38.4 1.4 1.9e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EQB60353.1 - 0.00033 21.2 0.4 0.00033 21.2 0.4 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YrzK PF17449.2 EQB60354.1 - 0.085 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized YrzK-like RVT_1 PF00078.27 EQB60355.1 - 1.2e-26 93.6 0.0 2.7e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3H2C3 PF17122.5 EQB60355.1 - 1.8 8.7 5.7 3.5 7.7 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger RVT_1 PF00078.27 EQB60357.1 - 3.3e-27 95.5 0.0 5.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CofC PF01983.16 EQB60357.1 - 0.015 14.5 0.1 0.13 11.4 0.0 2.3 2 0 0 2 2 2 0 Guanylyl transferase CofC like Tektin PF03148.14 EQB60358.1 - 0.015 14.1 3.5 0.13 11.0 0.5 2.0 1 1 1 2 2 2 0 Tektin family TORC_N PF12884.7 EQB60358.1 - 0.046 14.5 0.6 21 6.0 0.1 2.8 1 1 1 2 2 2 0 Transducer of regulated CREB activity, N terminus Ribosomal_S30AE PF02482.19 EQB60359.1 - 0.0076 17.0 1.6 0.02 15.7 1.2 1.9 1 1 1 2 2 2 1 Sigma 54 modulation protein / S30EA ribosomal protein LRR_8 PF13855.6 EQB60360.1 - 1e-09 38.0 39.3 0.00039 20.1 0.6 6.1 5 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 EQB60360.1 - 0.00017 21.9 58.1 0.018 15.5 12.1 8.0 7 1 2 9 9 9 4 Leucine Rich repeats (2 copies) DUF3837 PF12939.7 EQB60361.1 - 0.0083 16.5 1.0 0.012 16.0 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3837) GIIM PF08388.11 EQB60361.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Group II intron, maturase-specific domain SOAR PF16533.5 EQB60362.1 - 0.025 14.6 3.5 0.62 10.1 0.1 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region PilJ PF13675.6 EQB60362.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4337 PF14235.6 EQB60362.1 - 0.088 12.9 1.7 0.11 12.5 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Aldedh PF00171.22 EQB60362.1 - 0.098 11.1 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ribosomal_L29 PF00831.23 EQB60362.1 - 0.57 10.2 6.4 0.15 12.1 2.6 2.0 2 0 0 2 2 2 0 Ribosomal L29 protein TcdB_N PF12918.7 EQB60362.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.2 4 1 1 5 5 5 0 TcdB toxin N-terminal helical domain ApoLp-III PF07464.11 EQB60362.1 - 3.1 7.9 9.0 0.51 10.4 3.4 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RVT_1 PF00078.27 EQB60363.1 - 4.4e-06 26.4 0.2 5.3e-06 26.1 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_UL52 PF03121.15 EQB60364.1 - 0.00037 20.4 0.5 0.00072 19.5 0.5 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase CorC_HlyC PF03471.17 EQB60364.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Transporter associated domain PL48 PF15903.5 EQB60365.1 - 0.15 11.0 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 LRR_8 PF13855.6 EQB60366.1 - 9.4e-09 34.9 12.6 7.2e-06 25.7 2.2 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EQB60366.1 - 4.8e-06 26.8 16.4 0.00026 21.3 4.3 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB60366.1 - 0.00092 19.4 12.2 2.6 8.9 0.5 5.3 5 0 0 5 5 5 3 Leucine Rich Repeat DUF382 PF04037.13 EQB60366.1 - 0.046 13.9 0.4 0.11 12.7 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF382) LRR_6 PF13516.6 EQB60366.1 - 8.9 6.7 10.0 3 8.1 0.7 3.4 3 0 0 3 3 3 0 Leucine Rich repeat D5_N PF08706.11 EQB60367.1 - 5.9e-05 23.4 0.1 9.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 D5 N terminal like Imm30 PF15565.6 EQB60367.1 - 0.077 13.1 1.2 4.2 7.5 0.3 2.4 2 0 0 2 2 2 0 Immunity protein 30 UQ_con PF00179.26 EQB60368.1 - 3.6e-43 146.6 0.1 4.4e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EQB60368.1 - 0.00034 20.9 0.2 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 RWD domain Septin PF00735.18 EQB60371.1 - 1.4e-29 103.3 1.8 2e-29 102.7 1.8 1.2 1 0 0 1 1 1 1 Septin DER1 PF04511.15 EQB60373.1 - 2.5e-21 76.5 2.4 2.8e-21 76.3 2.4 1.0 1 0 0 1 1 1 1 Der1-like family Coilin_N PF15862.5 EQB60374.1 - 0.15 11.8 7.1 0.16 11.7 7.1 1.1 1 0 0 1 1 1 0 Coilin N-terminus HEAT PF02985.22 EQB60375.1 - 5.6e-07 29.3 0.2 0.58 10.6 0.0 6.8 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EQB60375.1 - 1.4e-06 28.6 0.0 0.72 10.3 0.0 4.7 3 2 2 5 5 5 2 HEAT repeats Tox-HDC PF15656.6 EQB60375.1 - 0.3 11.3 0.1 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature RRM_1 PF00076.22 EQB60376.1 - 9.9e-07 28.5 0.6 0.002 17.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EQB60376.1 - 0.0014 19.4 0.3 0.15 12.9 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat zf_CopZ PF18423.1 EQB60376.1 - 0.12 12.3 1.8 0.4 10.7 0.1 2.6 3 0 0 3 3 3 0 Zinc binding domain Baculo_19 PF04798.12 EQB60376.1 - 0.77 9.5 8.3 0.62 9.8 1.0 2.7 3 0 0 3 3 3 0 Baculovirus 19 kDa protein conserved region Ribosomal_S3_C PF00189.20 EQB60377.1 - 7.1e-18 64.9 0.5 1.2e-17 64.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Adeno_100 PF02438.16 EQB60377.1 - 0.12 10.5 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Late 100kD protein GLE1 PF07817.13 EQB60378.1 - 0.0003 20.1 12.0 0.00061 19.1 0.2 2.8 1 1 2 3 3 3 2 GLE1-like protein Ribonuc_2-5A PF06479.12 EQB60379.1 - 9.1e-30 103.4 0.0 2e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EQB60379.1 - 0.011 15.1 2.0 0.025 13.9 0.1 2.3 3 0 0 3 3 3 0 Protein kinase domain INT_SG_DDX_CT_C PF15300.6 EQB60379.1 - 0.077 12.8 0.1 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus RIO1 PF01163.22 EQB60380.1 - 5.7e-35 120.6 1.4 7.9e-35 120.2 1.4 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EQB60380.1 - 4.5e-06 26.8 0.0 9.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EQB60380.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phage_sheath_1C PF17482.2 EQB60380.1 - 0.03 14.3 1.9 0.65 10.0 0.0 3.3 3 1 0 3 3 3 0 Phage tail sheath C-terminal domain Kdo PF06293.14 EQB60380.1 - 0.082 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_45 PF14947.6 EQB60380.1 - 0.13 12.2 0.3 0.13 12.2 0.3 2.2 2 1 0 2 2 2 0 Winged helix-turn-helix Ribosomal_S28e PF01200.18 EQB60381.1 - 1e-18 67.0 0.1 1.2e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Utp11 PF03998.13 EQB60382.1 - 0.0041 17.1 14.5 0.027 14.4 10.0 2.2 1 1 1 2 2 2 2 Utp11 protein DUF2185 PF09951.9 EQB60382.1 - 0.036 13.9 0.3 0.066 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) ANAPC16 PF17256.2 EQB60382.1 - 0.045 14.1 1.4 0.23 11.8 1.1 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, subunit 16 NYD-SP28_assoc PF14775.6 EQB60382.1 - 0.16 12.1 6.1 1 9.5 0.5 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF4200 PF13863.6 EQB60382.1 - 0.99 9.8 21.3 75 3.8 21.3 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CDC45 PF02724.14 EQB60383.1 - 0.063 11.6 17.0 0.065 11.5 17.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 EQB60383.1 - 0.34 10.9 7.7 0.49 10.4 7.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CBM_19 PF03427.13 EQB60383.1 - 0.57 10.2 5.2 1.5 8.8 5.2 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain (family 19) DUF2052 PF09747.9 EQB60383.1 - 1 9.5 18.9 1.2 9.2 18.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 EQB60383.1 - 2.5 8.2 9.2 3 7.9 9.2 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 EQB60383.1 - 2.7 6.0 11.6 2.8 6.0 11.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.12 EQB60383.1 - 2.8 7.3 18.4 3.4 7.0 18.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 EQB60383.1 - 8.2 5.3 13.2 9.5 5.1 13.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Striatin PF08232.12 EQB60383.1 - 9.6 6.8 16.9 12 6.5 16.9 1.1 1 0 0 1 1 1 0 Striatin family MOZ_SAS PF01853.18 EQB60386.1 - 2.4e-16 59.9 7.3 1.8e-14 53.8 0.6 2.7 2 1 1 3 3 3 2 MOZ/SAS family zf-MYST PF17772.1 EQB60386.1 - 0.0003 20.3 2.2 0.00083 18.9 2.2 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EQB60386.1 - 0.016 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol3_delta2 PF13177.6 EQB60387.1 - 5.1e-17 62.1 0.6 4.2e-13 49.4 0.5 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EQB60387.1 - 5.1e-15 56.1 0.3 1.7e-14 54.4 0.1 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EQB60387.1 - 2.6e-09 37.4 0.0 6.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 EQB60387.1 - 2.1e-07 31.3 0.6 0.0014 18.9 0.0 3.4 2 2 2 4 4 4 2 AAA domain AAA_assoc_2 PF16193.5 EQB60387.1 - 7.7e-07 29.4 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 EQB60387.1 - 8.4e-07 29.1 0.0 2.4e-06 27.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 EQB60387.1 - 3.7e-06 27.0 0.2 3.7e-06 27.0 0.2 1.9 2 1 0 2 2 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EQB60387.1 - 1.1e-05 25.2 0.0 1.9e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EQB60387.1 - 5.2e-05 23.7 0.0 0.00029 21.3 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EQB60387.1 - 0.00011 21.7 0.0 0.00071 19.0 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EQB60387.1 - 0.00026 20.9 0.9 0.065 13.1 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.6 EQB60387.1 - 0.00027 20.7 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EQB60387.1 - 0.0003 20.8 0.1 0.0013 18.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 EQB60387.1 - 0.0003 20.6 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EQB60387.1 - 0.00038 21.0 0.1 0.00069 20.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EQB60387.1 - 0.00072 19.0 0.3 1.1 8.7 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein AAA_3 PF07726.11 EQB60387.1 - 0.0034 17.2 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EQB60387.1 - 0.0039 16.3 0.1 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EQB60387.1 - 0.0052 16.9 0.1 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EQB60387.1 - 0.0059 16.3 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain DNA_pol3_delta PF06144.13 EQB60387.1 - 0.0062 16.3 0.3 0.016 15.0 0.3 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 EQB60387.1 - 0.0068 16.8 0.1 0.022 15.1 0.1 2.0 1 1 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EQB60387.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EQB60387.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EQB60387.1 - 0.019 15.5 0.3 0.047 14.2 0.3 1.9 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 EQB60387.1 - 0.031 14.1 0.6 0.078 12.7 0.5 1.7 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EQB60387.1 - 0.04 13.9 0.1 0.86 9.6 0.0 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EQB60387.1 - 0.042 14.2 0.4 0.25 11.7 0.1 1.9 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EQB60387.1 - 0.049 12.8 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EQB60387.1 - 0.054 13.2 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EQB60387.1 - 0.056 13.6 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EQB60387.1 - 0.057 13.3 0.3 0.17 11.8 0.1 1.8 1 1 1 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 EQB60387.1 - 0.079 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EQB60387.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 EQB60387.1 - 0.14 11.6 0.3 4.8 6.6 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein DEAD PF00270.29 EQB60387.1 - 0.31 10.8 1.9 2 8.1 0.1 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase GTP_EFTU PF00009.27 EQB60390.1 - 2.9e-38 131.4 1.7 4.1e-38 130.9 1.7 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EQB60390.1 - 4.9e-06 26.6 0.2 1.7e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Collectrin PF16959.5 EQB60390.1 - 0.0051 16.6 0.8 0.0051 16.6 0.8 1.8 2 0 0 2 2 2 1 Renal amino acid transporter Ras PF00071.22 EQB60390.1 - 0.016 14.8 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 Ras family UNC45-central PF11701.8 EQB60390.1 - 0.22 11.5 1.8 0.88 9.5 1.7 2.0 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central EFG_C PF00679.24 EQB60391.1 - 7.5e-06 25.9 0.4 8.9e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 Elongation factor G C-terminus zf-C3HC4_4 PF15227.6 EQB60392.1 - 1.1e-09 38.3 15.0 2.7e-09 37.1 15.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EQB60392.1 - 1.9e-09 37.2 12.7 4.8e-09 35.9 12.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EQB60392.1 - 5.4e-08 32.6 10.7 1.2e-07 31.5 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EQB60392.1 - 7.3e-08 32.3 16.0 1.3e-07 31.5 12.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EQB60392.1 - 1.4e-07 31.7 15.3 1.8e-07 31.4 14.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EQB60392.1 - 1.8e-07 30.9 13.7 1.8e-07 30.9 13.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB60392.1 - 9.2e-06 25.5 10.8 9.2e-06 25.5 10.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EQB60392.1 - 4.5e-05 23.2 11.6 0.00015 21.6 11.5 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 EQB60392.1 - 0.0043 17.2 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 EQB60392.1 - 0.017 15.4 13.9 0.25 11.7 14.2 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger domain Spt4 PF06093.13 EQB60392.1 - 0.045 13.9 2.1 0.071 13.2 0.2 2.0 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger zf-ANAPC11 PF12861.7 EQB60392.1 - 0.047 13.7 7.5 0.094 12.8 7.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EQB60392.1 - 0.095 12.3 10.3 0.19 11.4 10.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EQB60392.1 - 2.2 8.1 14.5 25 4.8 15.0 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EQB60392.1 - 2.8 8.1 9.3 4.6 7.4 7.7 2.1 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-LITAF-like PF10601.9 EQB60392.1 - 4.9 7.5 20.0 3.1 8.1 11.5 2.9 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain HRDC PF00570.23 EQB60393.1 - 7.1e-05 22.7 0.0 0.00024 21.0 0.0 1.8 2 0 0 2 2 2 1 HRDC domain Acetyltransf_1 PF00583.25 EQB60394.1 - 3e-17 62.9 0.0 3.4e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EQB60394.1 - 1.5e-11 44.6 0.2 2.1e-11 44.0 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EQB60394.1 - 1.1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EQB60394.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EQB60394.1 - 0.0026 17.9 0.1 0.0031 17.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EQB60394.1 - 0.0027 17.8 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EQB60394.1 - 0.025 14.7 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TBPIP_N PF15517.6 EQB60394.1 - 0.055 13.5 0.3 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 TBP-interacting protein N-terminus TPR_1 PF00515.28 EQB60395.1 - 0.00011 21.9 21.6 1 9.3 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EQB60395.1 - 0.00012 22.5 0.1 18 5.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EQB60395.1 - 0.00021 21.2 20.3 0.32 11.3 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EQB60395.1 - 0.00041 20.2 19.1 1.7 8.9 0.1 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EQB60395.1 - 0.0013 19.0 1.3 0.69 10.2 0.5 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat Rubredoxin_C PF18267.1 EQB60395.1 - 0.1 12.5 1.4 4.9 7.2 0.1 3.3 2 1 1 3 3 3 0 Rubredoxin NAD+ reductase C-terminal domain TPR_17 PF13431.6 EQB60395.1 - 0.51 10.9 5.2 1.3 9.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EQB60395.1 - 0.67 10.2 9.4 12 6.2 0.2 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 WD40 PF00400.32 EQB60396.1 - 2.8e-06 28.0 0.1 0.085 13.8 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 EQB60396.1 - 0.00056 19.9 2.7 0.62 10.1 0.0 3.6 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EQB60396.1 - 0.0029 17.9 0.9 2.8 8.3 0.0 4.1 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.10 EQB60396.1 - 0.0057 16.4 1.1 0.011 15.4 0.2 2.0 1 1 1 2 2 2 1 UTP15 C terminal GvpD PF07088.11 EQB60396.1 - 0.045 12.4 0.4 4.5 5.8 0.0 2.1 2 0 0 2 2 2 0 GvpD gas vesicle protein DUF4891 PF16232.5 EQB60396.1 - 0.38 11.3 5.8 1.4 9.5 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4891) DUF4538 PF15061.6 EQB60396.1 - 0.48 10.2 3.7 0.23 11.2 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF3242 PF11586.8 EQB60398.1 - 0.26 11.0 4.4 0.34 10.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) Pescadillo_N PF06732.11 EQB60399.1 - 1.9e-19 70.3 11.2 1.9e-19 70.3 11.2 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EQB60399.1 - 3.4e-11 43.4 1.7 8e-11 42.2 1.7 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EQB60399.1 - 0.0073 16.7 4.4 0.011 16.0 1.6 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Kinesin PF00225.23 EQB60400.1 - 4.3e-78 262.6 5.1 6.8e-78 261.9 5.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EQB60400.1 - 8.7e-16 58.2 0.8 8.7e-16 58.2 0.8 2.6 3 0 0 3 3 3 1 Microtubule binding AAA_22 PF13401.6 EQB60400.1 - 0.13 12.5 0.8 0.49 10.7 0.6 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EQB60400.1 - 0.94 9.5 4.0 1.1 9.2 1.4 2.4 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit CTP_synth_N PF06418.14 EQB60401.1 - 5.9e-101 337.2 1.2 8.9e-101 336.6 1.2 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EQB60401.1 - 1.2e-45 155.6 0.0 2.6e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EQB60401.1 - 4.2e-10 39.7 0.0 8.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 EQB60401.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SWIRM PF04433.17 EQB60404.1 - 1e-18 67.5 0.9 4.6e-18 65.4 0.9 1.9 1 1 0 1 1 1 1 SWIRM domain SWIRM PF04433.17 EQB60405.1 - 4.7e-12 46.1 7.9 2.8e-11 43.6 7.7 3.9 4 1 1 5 5 5 2 SWIRM domain Myb_DNA-binding PF00249.31 EQB60405.1 - 9e-11 41.8 0.2 1.9e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EQB60405.1 - 1.3e-06 28.5 0.0 4.9e-06 26.7 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.14 EQB60405.1 - 1.7 9.4 5.2 3 8.6 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 UCH PF00443.29 EQB60406.1 - 1.2e-18 67.5 21.6 2e-16 60.3 7.6 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EQB60406.1 - 1.3e-15 57.4 7.0 1.3e-15 57.4 7.0 4.2 5 0 0 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EQB60406.1 - 0.00096 18.8 24.5 0.00096 18.8 24.5 3.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF5380 PF17351.2 EQB60407.1 - 0.015 15.1 1.3 0.016 15.1 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5380) Fer2_BFD PF04324.15 EQB60408.1 - 0.00074 19.8 0.0 14 6.1 0.0 3.3 1 1 2 3 3 3 3 BFD-like [2Fe-2S] binding domain HTH_27 PF13463.6 EQB60408.1 - 0.038 14.5 0.2 2.3 8.8 0.1 2.6 1 1 1 2 2 2 0 Winged helix DNA-binding domain Spectrin_like PF18373.1 EQB60408.1 - 0.88 9.7 5.2 1.1 9.3 1.0 2.9 1 1 3 4 4 4 0 Spectrin like domain DUF3683 PF12447.8 EQB60408.1 - 0.96 9.6 6.6 4.5 7.4 0.4 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) ATP-synt_ab_C PF00306.27 EQB60408.1 - 3 8.2 8.8 0.97 9.8 1.0 3.0 1 1 2 3 3 3 0 ATP synthase alpha/beta chain, C terminal domain Caskin-tail PF16632.5 EQB60408.1 - 7.2 7.1 13.4 15 6.1 1.2 4.5 2 1 3 5 5 5 0 C-terminal region of Caskin DUF1870 PF08965.10 EQB60409.1 - 0.2 11.7 7.5 5.2 7.1 0.8 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1870) IL12p40_C PF10420.9 EQB60411.1 - 0.089 13.3 0.4 0.19 12.3 0.4 1.6 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus Prp18 PF02840.15 EQB60411.1 - 0.67 10.0 4.6 0.68 10.0 2.2 2.1 1 1 1 2 2 2 0 Prp18 domain MT0933_antitox PF14013.6 EQB60412.1 - 1.6e-05 25.1 7.3 3.5 8.0 6.0 4.4 2 1 1 3 3 3 1 MT0933-like antitoxin protein DUF5082 PF16888.5 EQB60412.1 - 2.5e-05 24.5 0.4 0.0006 20.1 0.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) ApoO PF09769.9 EQB60412.1 - 0.00039 20.4 0.1 0.054 13.5 0.0 2.9 1 1 1 2 2 2 1 Apolipoprotein O Baculo_PEP_C PF04513.12 EQB60412.1 - 0.00042 20.4 16.5 0.011 15.8 8.9 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2884 PF11101.8 EQB60412.1 - 0.00092 18.8 0.1 0.0015 18.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2884) RHD3 PF05879.12 EQB60412.1 - 0.0016 16.7 0.0 0.0017 16.6 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DUF948 PF06103.11 EQB60412.1 - 0.0037 17.5 16.7 0.055 13.7 2.9 3.3 1 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EQB60412.1 - 0.0059 16.6 1.8 0.39 10.8 0.2 2.7 1 1 0 2 2 2 1 Protein of unknown function (DUF1664) Collagen_mid PF15984.5 EQB60412.1 - 0.011 15.5 10.8 0.044 13.5 10.5 2.0 1 1 1 2 2 2 0 Bacterial collagen, middle region Apolipoprotein PF01442.18 EQB60412.1 - 0.014 15.3 0.0 0.032 14.1 0.0 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EQB60412.1 - 0.015 15.4 5.9 0.043 13.9 2.2 2.5 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.11 EQB60412.1 - 0.018 15.1 0.8 3.3 7.7 0.1 2.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Fzo_mitofusin PF04799.13 EQB60412.1 - 0.022 14.3 0.1 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 fzo-like conserved region Allexi_40kDa PF05549.11 EQB60412.1 - 0.026 14.1 0.6 0.071 12.6 0.3 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein Herpes_UL6 PF01763.16 EQB60412.1 - 0.041 12.4 1.9 0.055 12.0 1.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Sipho_Gp157 PF05565.11 EQB60412.1 - 0.045 13.8 0.3 1.5 8.9 0.0 2.5 1 1 2 3 3 3 0 Siphovirus Gp157 CsbD PF05532.12 EQB60412.1 - 0.047 13.6 1.6 15 5.6 0.1 3.5 1 1 3 4 4 4 0 CsbD-like Prominin PF05478.11 EQB60412.1 - 0.054 11.5 0.8 0.078 10.9 0.8 1.4 1 1 0 1 1 1 0 Prominin NPV_P10 PF05531.12 EQB60412.1 - 0.069 13.6 14.4 0.057 13.9 3.2 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mer2 PF09074.10 EQB60412.1 - 0.079 12.8 0.9 0.1 12.4 0.9 1.3 1 0 0 1 1 1 0 Mer2 DASH_Duo1 PF08651.10 EQB60412.1 - 0.094 12.5 2.1 5 7.0 0.1 3.9 2 2 3 5 5 5 0 DASH complex subunit Duo1 RmuC PF02646.16 EQB60412.1 - 0.096 11.8 0.7 4 6.5 0.1 2.4 1 1 0 2 2 2 0 RmuC family FlaC_arch PF05377.11 EQB60412.1 - 0.12 12.8 2.3 6.6 7.2 0.2 4.1 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) YtxH PF12732.7 EQB60412.1 - 0.14 12.7 3.4 24 5.6 3.4 3.2 1 1 0 1 1 1 0 YtxH-like protein SOAR PF16533.5 EQB60412.1 - 0.16 11.9 0.1 6 6.9 0.0 2.8 1 1 2 3 3 3 0 STIM1 Orai1-activating region PSII_Pbs27 PF13326.6 EQB60412.1 - 0.23 11.8 1.2 0.51 10.6 1.2 1.6 1 1 0 1 1 1 0 Photosystem II Pbs27 Mit_KHE1 PF10173.9 EQB60412.1 - 0.25 11.4 0.0 0.54 10.3 0.0 1.7 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Chlorosome_CsmC PF11098.8 EQB60412.1 - 0.29 11.1 12.4 0.62 10.0 11.3 2.1 1 1 1 2 2 2 0 Chlorosome envelope protein C Phage_holin_7_1 PF16081.5 EQB60412.1 - 0.31 11.2 6.9 0.32 11.2 4.0 2.1 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Laminin_II PF06009.12 EQB60412.1 - 0.5 10.4 4.1 2.6 8.1 0.4 2.3 1 1 0 2 2 2 0 Laminin Domain II UPF0184 PF03670.13 EQB60412.1 - 0.7 10.3 5.5 0.74 10.2 0.3 2.9 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0184) Perilipin PF03036.16 EQB60412.1 - 0.71 8.8 4.7 0.94 8.4 2.8 2.0 1 1 1 2 2 2 0 Perilipin family TSP_C PF05735.12 EQB60415.1 - 0.051 13.5 3.9 4.9 7.0 0.0 3.8 3 2 1 5 5 5 0 Thrombospondin C-terminal region DUF2483 PF10656.9 EQB60415.1 - 0.099 12.9 0.1 0.099 12.9 0.1 3.6 3 2 1 4 4 4 0 Hypothetical protein of unknown function (DUF2483) TSP_C PF05735.12 EQB60416.1 - 0.0041 17.1 1.5 3.5 7.5 0.0 3.5 2 2 1 4 4 4 2 Thrombospondin C-terminal region DUF2483 PF10656.9 EQB60416.1 - 0.073 13.3 0.1 0.073 13.3 0.1 4.0 5 2 1 6 6 6 0 Hypothetical protein of unknown function (DUF2483) Bap31 PF05529.12 EQB60417.1 - 2.2e-15 56.7 5.6 3.9e-15 55.9 5.6 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region GrpE PF01025.19 EQB60417.1 - 0.0022 17.7 2.6 0.0036 17.0 2.6 1.3 1 0 0 1 1 1 1 GrpE Rab5-bind PF09311.11 EQB60417.1 - 0.004 16.6 3.7 0.0051 16.3 3.7 1.1 1 0 0 1 1 1 1 Rabaptin-like protein Bap31_Bap29_C PF18035.1 EQB60417.1 - 0.005 16.8 4.2 0.005 16.8 4.2 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DASH_Spc34 PF08657.10 EQB60417.1 - 0.022 14.6 2.2 0.029 14.2 2.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Calcipressin PF04847.12 EQB60417.1 - 0.41 10.4 2.0 0.6 9.8 0.3 2.1 2 1 1 3 3 3 0 Calcipressin DNA_pol_D_N PF18018.1 EQB60418.1 - 0.069 13.2 5.5 2.1 8.5 5.5 2.8 1 1 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain SHNi-TPR PF10516.9 EQB60419.1 - 3.9e-10 39.0 0.4 2.1e-08 33.5 0.0 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_2 PF07719.17 EQB60419.1 - 1.8e-09 37.0 3.8 0.033 14.3 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EQB60419.1 - 4.5e-09 35.8 3.3 0.014 15.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EQB60419.1 - 1.1e-08 34.6 8.8 0.00048 20.1 0.8 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EQB60419.1 - 1.5e-08 34.8 0.3 0.0024 18.1 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EQB60419.1 - 1.1e-06 28.3 0.3 0.02 14.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EQB60419.1 - 0.00015 22.2 0.8 1.9 9.3 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EQB60419.1 - 0.0003 21.3 0.1 0.087 13.3 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EQB60419.1 - 0.00045 20.8 0.0 0.025 15.4 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EQB60419.1 - 0.0017 18.2 0.3 4.4 7.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EQB60419.1 - 0.0037 17.2 0.0 0.016 15.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EQB60419.1 - 0.006 17.2 0.0 0.21 12.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EQB60419.1 - 0.011 15.9 5.3 0.079 13.2 0.2 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EQB60419.1 - 0.011 15.4 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 EQB60419.1 - 0.014 15.7 5.0 18 6.0 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EQB60419.1 - 0.03 14.0 0.6 2 8.2 0.0 3.7 3 1 1 4 4 4 0 TPR repeat MAGE PF01454.19 EQB60420.1 - 0.009 15.7 4.0 0.021 14.5 4.0 1.7 1 1 0 1 1 1 1 MAGE family Inos-1-P_synth PF01658.17 EQB60420.1 - 0.31 11.3 5.9 0.11 12.8 1.5 2.2 2 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase vATP-synt_E PF01991.18 EQB60423.1 - 8.9e-19 67.7 16.2 4.8e-18 65.3 16.2 1.9 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit UPAR_LY6_2 PF16975.5 EQB60424.1 - 0.041 14.1 0.2 0.089 13.0 0.2 1.6 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 Actin PF00022.19 EQB60425.1 - 3.3e-05 22.7 0.0 4.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EQB60425.1 - 0.028 13.2 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Actin PF00022.19 EQB60426.1 - 9.3e-05 21.2 0.1 0.0022 16.6 0.1 2.0 1 1 0 1 1 1 1 Actin Ndc80_HEC PF03801.13 EQB60426.1 - 0.12 12.0 2.1 0.34 10.5 0.2 2.2 2 0 0 2 2 2 0 HEC/Ndc80p family MAP65_ASE1 PF03999.12 EQB60427.1 - 1.3e-10 40.6 4.2 1.5e-10 40.5 4.2 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Methyltrans_SAM PF10672.9 EQB60427.1 - 0.048 12.8 0.1 0.051 12.7 0.1 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Aa_trans PF01490.18 EQB60428.1 - 2.9e-26 92.1 35.8 3.9e-26 91.7 35.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CorA PF01544.18 EQB60428.1 - 0.2 11.0 7.8 0.46 9.8 7.0 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Ham1p_like PF01725.16 EQB60429.1 - 1.2e-27 97.1 0.4 4.1e-20 72.5 0.0 2.4 2 1 0 2 2 2 2 Ham1 family Ham1p_like PF01725.16 EQB60430.1 - 1.4e-07 31.6 0.7 4.8e-05 23.4 0.2 2.5 2 1 1 3 3 3 2 Ham1 family Cyclase_polyket PF04673.12 EQB60430.1 - 0.063 13.5 0.5 0.66 10.2 0.0 2.2 2 0 0 2 2 2 0 Polyketide synthesis cyclase Agglutinin_C PF18021.1 EQB60430.1 - 0.18 12.3 2.4 3.8 8.1 0.3 2.6 3 0 0 3 3 3 0 Agglutinin C-terminal PolyA_pol PF01743.20 EQB60433.1 - 5.9e-15 55.8 0.0 6.3e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Poly A polymerase head domain SRP1_TIP1 PF00660.17 EQB60433.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Seripauperin and TIP1 family Hist_deacetyl PF00850.19 EQB60434.1 - 3.1e-83 279.8 0.4 5.1e-83 279.1 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain eRF1_1 PF03463.15 EQB60435.1 - 7.2e-32 110.1 0.2 1.2e-31 109.3 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EQB60435.1 - 0.00049 20.6 0.5 0.45 11.0 0.0 2.5 1 1 1 2 2 2 2 eRF1 domain 3 Carb_kinase PF01256.17 EQB60436.1 - 8.9e-26 90.8 0.0 1e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Homeodomain PF00046.29 EQB60437.1 - 3.8e-16 58.7 3.0 5.9e-16 58.1 3.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EQB60437.1 - 0.00044 20.1 1.6 0.0012 18.8 1.6 1.8 1 1 0 1 1 1 1 Homeobox KN domain Phage_terminase PF10668.9 EQB60437.1 - 0.043 13.8 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Phage terminase small subunit DUF3844 PF12955.7 EQB60437.1 - 0.097 12.8 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) YdaS_antitoxin PF15943.5 EQB60437.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT UPF0160 PF03690.13 EQB60438.1 - 5.6e-24 85.4 0.0 6.1e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) zf-RING_2 PF13639.6 EQB60439.1 - 2e-11 44.0 7.9 2e-11 44.0 7.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB60439.1 - 1.9e-08 34.0 7.3 1.9e-08 34.0 7.3 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EQB60439.1 - 3.6e-08 33.6 6.1 3.6e-08 33.6 6.1 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EQB60439.1 - 2.4e-07 30.5 5.7 2.4e-07 30.5 5.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB60439.1 - 2.6e-07 30.5 5.8 2.6e-07 30.5 5.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EQB60439.1 - 8.7e-07 28.6 8.8 2.4e-06 27.1 8.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EQB60439.1 - 6.4e-06 25.9 3.5 6.4e-06 25.9 3.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EQB60439.1 - 9.2e-06 25.6 1.8 9.2e-06 25.6 1.8 2.7 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EQB60439.1 - 0.00017 21.4 5.2 0.00017 21.4 5.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EQB60439.1 - 0.0013 18.7 1.5 0.0013 18.7 1.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Jagunal PF07086.12 EQB60439.1 - 0.042 13.9 0.4 0.084 12.9 0.4 1.4 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis RINGv PF12906.7 EQB60439.1 - 0.062 13.4 2.6 0.22 11.7 2.6 2.0 1 1 0 1 1 1 0 RING-variant domain DiS_P_DiS PF06750.13 EQB60439.1 - 0.22 11.6 4.9 0.62 10.2 0.0 3.2 4 0 0 4 4 4 0 Bacterial Peptidase A24 N-terminal domain Zf_RING PF16744.5 EQB60439.1 - 0.33 11.1 8.4 1.2 9.3 3.1 2.6 2 1 0 2 2 2 0 KIAA1045 RING finger zf-RING_4 PF14570.6 EQB60439.1 - 0.72 9.7 8.6 2.9 7.8 5.2 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 EQB60439.1 - 1.9 8.6 14.6 0.37 10.9 7.0 2.8 2 0 0 2 2 2 0 Zinc-finger Zn_ribbon_17 PF17120.5 EQB60439.1 - 1.9 8.2 10.2 0.092 12.4 4.7 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type SLD5_C PF16922.5 EQB60440.1 - 0.0076 16.4 0.1 0.011 15.9 0.1 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus DUF761 PF05553.11 EQB60440.1 - 0.044 13.3 0.8 0.16 11.5 0.0 2.3 2 1 1 3 3 3 0 Cotton fibre expressed protein zf-RING_2 PF13639.6 EQB60441.1 - 3.3e-13 49.7 7.8 4.2e-13 49.4 7.8 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB60441.1 - 4.7e-10 39.1 6.7 7.3e-10 38.5 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EQB60441.1 - 2.2e-09 36.9 5.8 2.2e-09 36.9 5.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EQB60441.1 - 1.1e-08 35.2 9.8 3.3e-08 33.7 9.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EQB60441.1 - 3.1e-08 33.5 5.2 7.1e-07 29.2 1.2 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EQB60441.1 - 3.3e-07 30.1 5.9 4.4e-07 29.7 5.9 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EQB60441.1 - 6.9e-07 29.0 8.6 1.1e-06 28.4 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EQB60441.1 - 8.7e-06 25.5 5.9 1.3e-05 25.0 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EQB60441.1 - 0.00021 21.3 5.2 0.00089 19.3 5.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 EQB60441.1 - 0.00063 19.7 6.2 0.0015 18.5 6.2 1.6 1 1 0 1 1 1 1 Zinc-finger Prok-RING_4 PF14447.6 EQB60441.1 - 0.00067 19.5 6.1 0.0016 18.3 6.1 1.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EQB60441.1 - 0.001 18.6 7.5 0.0019 17.8 7.5 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EQB60441.1 - 0.0021 18.1 6.5 0.0064 16.6 6.5 1.7 1 1 0 1 1 1 1 RING-variant domain Zf_RING PF16744.5 EQB60441.1 - 0.003 17.6 2.8 0.003 17.6 2.8 2.0 1 1 1 2 2 2 1 KIAA1045 RING finger FANCL_C PF11793.8 EQB60441.1 - 0.013 15.7 8.9 0.27 11.4 8.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EQB60441.1 - 0.026 14.3 4.6 0.026 14.3 4.6 1.7 2 1 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EQB60441.1 - 0.052 13.3 4.9 0.11 12.4 4.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 EQB60441.1 - 0.086 13.1 5.0 0.13 12.5 1.2 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain PHD PF00628.29 EQB60441.1 - 0.58 10.1 7.2 2.5 8.1 7.3 1.9 1 1 1 2 2 2 0 PHD-finger zf-RING-like PF08746.11 EQB60441.1 - 0.85 10.0 7.0 1.6 9.1 7.0 1.5 1 1 0 1 1 1 0 RING-like domain Kazal_1 PF00050.21 EQB60441.1 - 0.95 9.5 9.1 0.91 9.6 1.0 2.8 1 1 1 2 2 2 0 Kazal-type serine protease inhibitor domain zf-C2H2_9 PF16293.5 EQB60441.1 - 1.7 8.6 11.2 2 8.3 5.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-P11 PF03854.14 EQB60441.1 - 3.7 7.3 10.2 23 4.7 10.3 2.0 1 1 1 2 2 2 0 P-11 zinc finger Met_10 PF02475.16 EQB60442.1 - 1.2e-26 93.7 0.4 2.6e-26 92.6 0.3 1.4 1 1 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EQB60442.1 - 1.4e-07 31.2 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.15 EQB60442.1 - 5.4e-05 23.0 0.5 5.4e-05 23.0 0.5 2.2 1 1 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 EQB60442.1 - 0.00057 19.5 0.1 0.00057 19.5 0.1 2.3 2 2 1 3 3 3 1 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 EQB60442.1 - 0.00073 18.6 0.5 0.0012 18.0 0.3 1.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EQB60442.1 - 0.0035 18.0 0.0 0.007 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EQB60442.1 - 0.01 16.5 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EQB60442.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EQB60442.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 EQB60442.1 - 0.028 13.6 0.6 0.046 12.9 0.2 1.4 1 1 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 EQB60442.1 - 0.035 13.9 0.4 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.11 EQB60442.1 - 0.038 13.5 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Cons_hypoth95 PF03602.15 EQB60442.1 - 0.046 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ribosomal_S17 PF00366.20 EQB60443.1 - 4.2e-22 78.0 1.4 8.1e-22 77.1 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 EQB60443.1 - 6e-18 65.0 0.4 1.3e-17 63.9 0.4 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal DUF1845 PF08900.11 EQB60443.1 - 0.031 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) DUF2258 PF10015.9 EQB60443.1 - 0.042 14.0 0.6 0.09 12.9 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) UQ_con PF00179.26 EQB60444.1 - 1.9e-46 157.2 0.0 2.2e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EQB60444.1 - 0.036 14.3 0.0 0.049 13.9 0.0 1.4 1 1 0 1 1 1 0 RWD domain DUF3792 PF12670.7 EQB60445.1 - 0.0077 16.4 1.6 0.0077 16.4 1.6 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3792) Ras PF00071.22 EQB60446.1 - 3e-51 173.2 1.6 3.8e-51 172.9 1.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB60446.1 - 1.3e-33 115.7 0.6 1.3e-33 115.7 0.6 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB60446.1 - 6.4e-14 51.8 0.5 1e-13 51.2 0.5 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EQB60446.1 - 8.2e-06 25.9 1.1 9e-06 25.8 0.2 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EQB60446.1 - 2.7e-05 23.7 0.9 4.4e-05 23.0 0.9 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EQB60446.1 - 3.7e-05 23.4 2.7 0.00063 19.3 2.7 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EQB60446.1 - 0.00019 21.4 1.6 0.4 10.6 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EQB60446.1 - 0.0035 16.8 2.6 0.0046 16.4 1.5 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.19 EQB60446.1 - 0.012 15.3 0.2 0.12 11.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EQB60446.1 - 0.024 14.9 0.1 0.38 11.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EQB60446.1 - 0.027 15.0 0.5 3.5 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EQB60446.1 - 0.049 13.3 1.8 0.27 10.9 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EQB60446.1 - 0.054 13.5 0.2 0.054 13.5 0.2 1.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EQB60446.1 - 0.081 12.4 0.5 0.13 11.8 0.5 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_21 PF13304.6 EQB60446.1 - 0.11 12.3 0.3 0.58 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Chorein_N PF12624.7 EQB60447.1 - 0.00071 19.7 0.1 0.00071 19.7 0.1 4.8 5 1 0 5 5 5 1 N-terminal region of Chorein or VPS13 Metallophos PF00149.28 EQB60448.1 - 3.3e-37 129.0 0.4 4.4e-37 128.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EQB60448.1 - 0.00035 20.9 0.1 0.00085 19.7 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Histone PF00125.24 EQB60449.1 - 1.2e-36 126.0 1.4 1.3e-36 125.8 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EQB60449.1 - 1.4e-05 25.3 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EQB60449.1 - 0.00011 22.3 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EQB60449.1 - 0.089 13.4 5.3 0.13 12.9 5.3 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Bromo_TP PF07524.13 EQB60449.1 - 0.096 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated ERO1 PF04137.15 EQB60450.1 - 0.0012 18.1 5.3 0.0015 17.8 5.3 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HrpF PF06266.12 EQB60450.1 - 0.067 13.5 0.3 0.11 12.8 0.3 1.3 1 0 0 1 1 1 0 HrpF protein TFIIS_M PF07500.14 EQB60451.1 - 1.1e-19 71.0 1.9 1.4e-19 70.6 1.6 1.3 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EQB60451.1 - 1.9e-18 66.0 3.6 3.5e-18 65.2 3.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Peptidase_C14 PF00656.22 EQB60451.1 - 0.022 14.7 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Caspase domain Ribosomal_L27e PF01777.18 EQB60453.1 - 9.7e-14 51.5 3.2 1.4e-13 51.0 3.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EQB60453.1 - 0.0045 16.9 0.1 0.0098 15.8 0.1 1.6 1 0 0 1 1 1 1 KOW motif Glyco_hydro_67M PF07488.12 EQB60453.1 - 0.029 13.5 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain B56 PF01603.20 EQB60454.1 - 2.7e-11 43.1 7.7 2.7e-11 43.1 7.7 2.2 1 1 1 3 3 3 1 Protein phosphatase 2A regulatory B subunit (B56 family) B56 PF01603.20 EQB60455.1 - 3.7e-10 39.4 3.4 4e-10 39.2 3.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) RPN1_C PF18051.1 EQB60456.1 - 8.1e-13 48.2 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EQB60456.1 - 0.00013 22.2 0.0 0.77 10.3 0.0 3.8 3 0 0 3 3 3 2 Proteasome/cyclosome repeat RPN1_RPN2_N PF17781.1 EQB60457.1 - 1e-11 44.9 6.7 1.7e-11 44.1 5.8 1.7 1 1 1 2 2 2 1 RPN1/RPN2 N-terminal domain AbbA_antirepres PF14156.6 EQB60457.1 - 8.4 6.4 10.2 0.23 11.4 0.4 2.8 3 0 0 3 3 3 0 Antirepressor AbbA PHM7_cyt PF14703.6 EQB60458.1 - 0.028 14.7 5.5 0.18 12.0 0.5 2.6 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_M1 PF01433.20 EQB60459.1 - 3.5e-81 271.9 1.3 7e-81 270.9 1.3 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EQB60459.1 - 2.3e-37 129.0 1.1 5.1e-37 127.9 0.8 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 EQB60459.1 - 1.5e-35 123.3 0.3 1.5e-35 123.3 0.3 1.5 2 0 0 2 2 2 1 ERAP1-like C-terminal domain WLM PF08325.10 EQB60459.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 WLM domain Sel1 PF08238.12 EQB60460.1 - 4.7e-23 81.1 2.7 7.2e-07 29.7 0.0 6.1 6 0 0 6 6 6 5 Sel1 repeat MRAP PF15183.6 EQB60461.1 - 0.0096 15.8 2.6 0.0096 15.8 2.6 1.6 1 1 0 1 1 1 1 Melanocortin-2 receptor accessory protein family APG12 PF04110.13 EQB60461.1 - 0.082 13.3 3.4 0.11 12.9 3.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 DUF4100 PF13352.6 EQB60461.1 - 0.27 11.0 7.1 0.29 10.9 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Fungal_KA1 PF16797.5 EQB60463.1 - 0.0053 16.5 0.4 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 Fungal kinase associated-1 domain ABC_tran PF00005.27 EQB60464.1 - 1.4e-27 96.9 0.0 3e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EQB60464.1 - 4.8e-07 29.9 1.6 0.00024 21.0 0.2 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 EQB60464.1 - 8.8e-07 28.8 15.0 1.3e-06 28.3 15.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 EQB60464.1 - 0.00035 20.3 0.2 0.00085 19.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EQB60464.1 - 0.00083 18.9 11.8 0.014 14.8 5.4 3.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EQB60464.1 - 0.0088 16.1 0.1 0.026 14.6 0.0 1.9 2 0 0 2 2 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 EQB60464.1 - 0.0092 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EQB60464.1 - 0.01 15.7 0.1 0.037 13.9 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 EQB60464.1 - 0.011 15.8 0.1 0.041 14.0 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 EQB60464.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KH_2 PF07650.17 EQB60464.1 - 0.027 14.3 0.1 0.093 12.6 0.1 1.9 1 0 0 1 1 1 0 KH domain AAA_23 PF13476.6 EQB60464.1 - 0.034 14.6 4.5 0.034 14.6 4.5 2.2 2 1 1 3 3 1 0 AAA domain AAA_22 PF13401.6 EQB60464.1 - 0.039 14.2 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EQB60464.1 - 0.055 12.8 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family LolA PF03548.15 EQB60464.1 - 0.065 12.9 1.5 0.12 12.1 1.5 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA NACHT PF05729.12 EQB60464.1 - 0.095 12.6 0.4 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EQB60464.1 - 0.14 12.7 0.0 0.42 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EQB60464.1 - 0.18 11.8 0.9 0.38 10.8 0.9 1.7 1 1 0 1 1 1 0 Dynamin family AAA_33 PF13671.6 EQB60464.1 - 0.21 11.7 0.0 0.48 10.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain Patatin PF01734.22 EQB60466.1 - 1.2e-20 74.6 0.0 1.8e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Synaptobrevin PF00957.21 EQB60468.1 - 9.1e-09 35.0 0.8 9.1e-09 35.0 0.8 1.7 2 0 0 2 2 2 1 Synaptobrevin DUF1744 PF08490.12 EQB60468.1 - 0.0015 17.2 0.1 0.0023 16.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) Phage_Gp23 PF10669.9 EQB60468.1 - 0.002 18.5 2.2 0.002 18.5 2.2 1.9 2 1 0 2 2 2 1 Protein gp23 (Bacteriophage A118) DUF4239 PF14023.6 EQB60468.1 - 0.049 13.4 0.5 0.075 12.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) tRNA_SAD PF07973.14 EQB60469.1 - 3.1e-14 52.8 0.2 7e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain GP57 PF17594.2 EQB60469.1 - 0.047 13.5 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 Ac110_PIF PF07280.11 EQB60469.1 - 0.087 12.6 0.3 0.25 11.1 0.3 1.8 1 0 0 1 1 1 0 Per os infectivity factor AC110 Lipocalin_4 PF13648.6 EQB60469.1 - 2.5 9.1 14.4 93 4.1 14.3 2.5 1 1 0 1 1 1 0 Lipocalin-like domain tRNA-synt_2c PF01411.19 EQB60470.1 - 6.2e-52 176.8 0.0 7.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) GHL6 PF14871.6 EQB60471.1 - 0.0083 16.3 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Erf4 PF10256.9 EQB60472.1 - 4e-07 30.1 2.5 1e-06 28.8 2.5 1.6 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RIO1 PF01163.22 EQB60473.1 - 5.3e-10 39.2 0.5 7.7e-10 38.7 0.5 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EQB60473.1 - 2.5e-08 33.6 3.7 3.5e-08 33.1 3.7 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EQB60473.1 - 0.0004 20.4 0.0 0.011 15.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EQB60473.1 - 0.0014 18.0 0.4 0.0042 16.4 0.4 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EQB60473.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2732 PF10809.8 EQB60473.1 - 0.078 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Methyltransf_25 PF13649.6 EQB60475.1 - 3.5e-12 46.9 0.0 6.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EQB60475.1 - 3.2e-11 43.7 0.0 5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EQB60475.1 - 7.5e-07 29.8 0.0 1.8e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EQB60475.1 - 1.1e-06 28.6 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EQB60475.1 - 2.3e-06 27.6 0.0 5.6e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EQB60475.1 - 1.8e-05 24.4 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 EQB60475.1 - 4.2e-05 23.0 0.0 7.3e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EQB60475.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EQB60475.1 - 0.0048 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EQB60475.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EQB60475.1 - 0.06 13.3 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 EQB60476.1 - 4.9e-61 205.0 0.3 2e-45 154.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EQB60476.1 - 3.6e-15 55.5 0.0 1.8e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EQB60476.1 - 1e-10 42.3 0.8 0.003 17.9 0.1 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EQB60476.1 - 5.5e-10 39.6 6.3 0.026 14.8 0.2 5.1 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.6 EQB60476.1 - 1e-09 38.5 0.5 0.00066 19.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.14 EQB60476.1 - 3e-09 37.2 0.0 4.5e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EQB60476.1 - 5.7e-08 32.7 0.0 0.0032 17.2 0.0 3.2 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EQB60476.1 - 3.1e-07 30.5 0.1 0.002 18.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EQB60476.1 - 3.9e-07 30.7 1.9 0.017 15.7 0.0 3.5 2 1 1 3 3 3 2 AAA domain NB-ARC PF00931.22 EQB60476.1 - 1.5e-06 27.6 0.1 0.41 9.8 0.0 3.6 4 0 0 4 4 4 2 NB-ARC domain RNA_helicase PF00910.22 EQB60476.1 - 1.5e-06 28.5 0.5 0.042 14.2 0.0 3.3 3 1 0 3 3 2 2 RNA helicase ABC_tran PF00005.27 EQB60476.1 - 2.1e-06 28.3 0.0 0.025 15.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.6 EQB60476.1 - 3.6e-06 27.4 0.2 0.056 13.9 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EQB60476.1 - 1e-05 25.7 0.0 0.069 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EQB60476.1 - 1.3e-05 24.6 2.4 0.0071 15.6 0.0 3.1 2 1 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 EQB60476.1 - 1.9e-05 24.5 0.0 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EQB60476.1 - 2.1e-05 24.3 0.0 0.11 12.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 EQB60476.1 - 3e-05 24.0 1.3 0.21 11.5 0.0 3.2 3 1 0 3 3 2 2 NACHT domain IstB_IS21 PF01695.17 EQB60476.1 - 5.2e-05 23.1 0.2 0.093 12.5 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.13 EQB60476.1 - 6e-05 22.3 0.2 0.091 11.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 EQB60476.1 - 0.00011 21.8 0.1 0.24 10.9 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 EQB60476.1 - 0.00013 21.4 0.1 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EQB60476.1 - 0.00015 22.1 0.1 0.39 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain Bac_DnaA PF00308.18 EQB60476.1 - 0.00027 20.8 4.4 2.3 8.0 4.6 3.3 2 1 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 EQB60476.1 - 0.00044 20.3 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EQB60476.1 - 0.00074 19.5 1.9 0.27 11.1 0.0 3.1 2 1 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 EQB60476.1 - 0.00093 18.9 0.0 0.33 10.6 0.0 2.6 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 EQB60476.1 - 0.0013 18.1 0.0 0.3 10.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EQB60476.1 - 0.0041 16.7 0.2 1.3 8.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EQB60476.1 - 0.0077 15.5 2.4 2.8 7.1 0.0 3.8 3 1 1 4 4 4 1 KAP family P-loop domain ATPase PF06745.13 EQB60476.1 - 0.017 14.5 3.6 0.1 11.9 0.0 3.3 3 2 1 4 4 3 0 KaiC RsgA_GTPase PF03193.16 EQB60476.1 - 0.017 15.0 1.5 0.35 10.8 0.0 3.0 2 1 1 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 EQB60476.1 - 0.018 14.9 7.2 0.39 10.6 0.0 3.6 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 EQB60476.1 - 0.024 14.0 0.2 15 4.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EQB60476.1 - 0.026 13.6 0.0 0.99 8.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PduV-EutP PF10662.9 EQB60476.1 - 0.031 14.0 0.0 6.5 6.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EQB60476.1 - 0.039 13.7 0.0 9.9 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EQB60476.1 - 0.041 13.8 0.5 8.9 6.2 0.0 3.1 2 1 1 3 3 3 0 NTPase PhoH PF02562.16 EQB60476.1 - 0.046 13.2 0.0 3.2 7.2 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein Sigma54_activ_2 PF14532.6 EQB60476.1 - 0.047 13.8 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 EQB60476.1 - 0.052 13.4 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EQB60476.1 - 0.053 13.3 0.3 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 EQB60476.1 - 0.058 13.1 0.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EQB60476.1 - 0.062 13.3 2.0 8.7 6.3 2.0 3.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EQB60476.1 - 0.11 12.8 0.1 9.9 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EQB60476.1 - 0.11 12.6 0.0 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Torsin tRNA-synt_1b PF00579.25 EQB60477.1 - 0.029 13.7 2.5 0.059 12.7 2.5 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (W and Y) Adeno_E3_CR1 PF02440.15 EQB60477.1 - 0.66 9.8 6.0 1.7 8.5 2.1 2.5 2 1 0 2 2 2 0 Adenovirus E3 region protein CR1 dUTPase PF00692.19 EQB60478.1 - 2.7e-26 91.8 0.0 3.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase WD40 PF00400.32 EQB60479.1 - 1.8e-12 47.6 2.8 0.031 15.1 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 EQB60479.1 - 9.7e-05 21.8 20.3 0.00047 19.6 4.5 3.1 1 1 2 3 3 3 3 WD40-like domain RAB3GAP2_N PF14655.6 EQB60479.1 - 0.0012 18.2 0.4 0.0016 17.8 0.4 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 EQB60480.1 - 2.4e-17 63.0 1.5 4.8e-05 24.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB60480.1 - 6.7e-08 32.7 0.1 0.12 12.7 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain ANAPC4_WD40 PF12894.7 EQB60481.1 - 0.015 15.6 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EQB60482.1 - 1.4e-08 33.9 4.5 1.7e-08 33.7 4.5 1.1 1 0 0 1 1 1 1 Nup133 N terminal like MAP65_ASE1 PF03999.12 EQB60483.1 - 6.9e-10 38.3 7.8 6.9e-10 38.3 7.8 3.3 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Sec20 PF03908.13 EQB60483.1 - 0.14 12.1 4.3 0.14 12.0 0.6 3.0 2 1 1 3 3 3 0 Sec20 Pik1 PF11522.8 EQB60483.1 - 9.3 6.3 6.3 12 6.0 0.2 3.1 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Sedlin_N PF04628.13 EQB60484.1 - 1.7e-05 25.0 2.6 2.1e-05 24.7 2.6 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region CBFD_NFYB_HMF PF00808.23 EQB60485.1 - 3e-09 37.0 0.0 5.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EQB60485.1 - 0.00088 19.6 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Acid_PPase PF12689.7 EQB60486.1 - 0.0026 17.6 0.3 0.13 12.1 0.3 2.3 2 1 0 2 2 2 1 Acid Phosphatase HAD_2 PF13419.6 EQB60486.1 - 0.0042 17.2 6.8 0.0088 16.1 6.8 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EQB60486.1 - 0.0065 16.8 0.0 0.32 11.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRM_4 PF10598.9 EQB60486.1 - 0.013 15.8 0.3 0.029 14.7 0.3 1.5 1 0 0 1 1 1 0 RNA recognition motif of the spliceosomal PrP8 Put_Phosphatase PF06888.12 EQB60486.1 - 0.041 13.3 0.4 0.092 12.1 0.4 1.6 1 1 0 1 1 1 0 Putative Phosphatase OHCU_decarbox PF09349.10 EQB60486.1 - 0.16 12.4 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 OHCU decarboxylase DUF2608 PF11019.8 EQB60486.1 - 0.95 8.9 7.3 0.42 10.0 1.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) FtsJ PF01728.19 EQB60487.1 - 1.5e-16 61.0 0.0 1.8e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Shal-type PF11601.8 EQB60487.1 - 0.043 13.3 0.6 0.068 12.7 0.6 1.3 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal eIF-5_eIF-2B PF01873.17 EQB60488.1 - 1.7e-30 105.3 3.2 2.2e-30 104.9 3.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 HMG-CoA_red PF00368.18 EQB60489.1 - 1.2e-93 314.1 0.2 1.4e-93 313.8 0.2 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF155 PF02582.14 EQB60490.1 - 6.3e-50 169.7 0.7 6.3e-50 169.7 0.7 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 SesA PF17107.5 EQB60490.1 - 0.023 14.9 0.2 0.3 11.3 0.0 2.3 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF16 PF01519.16 EQB60490.1 - 0.27 11.7 4.3 1.3 9.5 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 SIS PF01380.22 EQB60494.1 - 3.1e-35 120.9 0.1 7.8e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 SIS domain COPI_C PF06957.11 EQB60495.1 - 0.00018 20.4 0.3 0.00018 20.4 0.3 1.3 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus RecR PF02132.15 EQB60495.1 - 0.024 14.2 1.1 0.039 13.5 1.1 1.4 1 0 0 1 1 1 0 RecR protein zf-tcix PF14952.6 EQB60495.1 - 0.21 11.2 4.3 0.5 10.0 4.3 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding HECT PF00632.25 EQB60496.1 - 3.2e-05 23.6 0.2 6e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LRR_4 PF12799.7 EQB60497.1 - 2.9e-44 148.3 175.7 1.2e-07 31.9 1.0 14.2 7 2 6 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60497.1 - 3.2e-44 148.5 144.3 2.3e-07 30.5 11.6 13.6 7 4 8 15 15 15 14 Leucine rich repeat LRR_9 PF14580.6 EQB60497.1 - 0.27 10.7 89.1 0.011 15.3 5.1 8.5 1 1 7 9 9 9 0 Leucine-rich repeat adh_short PF00106.25 EQB60498.1 - 1.7e-16 60.3 0.0 3.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EQB60498.1 - 5.3e-09 36.0 0.0 5.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EQB60498.1 - 3e-05 23.6 0.0 5.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EQB60498.1 - 0.0041 16.8 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 EQB60498.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 EQB60498.1 - 0.27 11.1 0.0 0.42 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding IF4E PF01652.18 EQB60499.1 - 2.1e-21 76.4 1.4 2.6e-21 76.1 1.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TRAPP PF04051.16 EQB60500.1 - 1.3e-08 34.6 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Forkhead PF00250.18 EQB60501.1 - 6.8e-33 112.8 0.5 1.4e-32 111.8 0.2 1.7 2 0 0 2 2 2 1 Forkhead domain Linker_histone PF00538.19 EQB60501.1 - 0.032 14.6 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family Ribosomal_L15e PF00827.17 EQB60502.1 - 8.2e-80 267.0 5.2 9.3e-80 266.9 5.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 AAA PF00004.29 EQB60503.1 - 6.6e-14 52.5 0.1 1.3e-13 51.5 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EQB60503.1 - 8.8e-07 29.5 0.0 0.00021 21.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EQB60503.1 - 0.00032 20.7 0.2 0.00052 20.0 0.2 1.5 1 1 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EQB60503.1 - 0.00048 20.1 3.0 0.0049 16.8 0.2 2.5 1 1 1 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 EQB60503.1 - 0.0015 17.9 0.5 0.17 11.3 0.1 2.5 1 1 1 2 2 2 1 Bacterial TniB protein AAA_25 PF13481.6 EQB60503.1 - 0.0019 17.8 0.1 0.0071 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EQB60503.1 - 0.002 18.2 0.0 0.004 17.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EQB60503.1 - 0.0039 16.7 0.4 0.021 14.3 0.3 2.2 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EQB60503.1 - 0.0065 16.8 0.2 0.041 14.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EQB60503.1 - 0.0065 16.4 0.2 0.0087 16.0 0.1 1.4 1 1 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 EQB60503.1 - 0.007 16.1 1.8 0.15 11.8 1.8 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EQB60503.1 - 0.0082 16.2 0.1 0.051 13.6 0.1 2.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EQB60503.1 - 0.01 15.6 0.3 0.015 15.0 0.3 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EQB60503.1 - 0.01 15.6 0.2 0.026 14.2 0.1 1.6 1 1 1 2 2 2 0 IstB-like ATP binding protein PEPCK_ATP PF01293.20 EQB60503.1 - 0.012 14.3 0.5 0.56 8.8 0.0 2.1 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxykinase AAA_5 PF07728.14 EQB60503.1 - 0.015 15.3 0.2 0.037 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EQB60503.1 - 0.017 15.0 1.3 0.26 11.2 0.3 2.3 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 EQB60503.1 - 0.037 14.4 0.1 0.094 13.1 0.0 1.7 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 EQB60503.1 - 0.042 13.5 0.2 0.069 12.8 0.2 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 EQB60503.1 - 0.044 13.0 3.8 0.041 13.1 0.7 2.0 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 EQB60503.1 - 0.053 13.7 0.2 0.48 10.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EQB60503.1 - 0.066 12.4 0.5 0.14 11.3 0.4 1.6 2 0 0 2 2 2 0 NB-ARC domain DnaB_C PF03796.15 EQB60503.1 - 0.075 12.4 0.3 0.16 11.3 0.2 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 EQB60503.1 - 0.076 13.4 2.4 0.59 10.5 2.0 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EQB60503.1 - 0.085 12.9 0.5 0.22 11.6 0.5 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EQB60503.1 - 0.093 12.0 3.6 0.094 12.0 0.3 2.3 3 0 0 3 3 3 0 Zeta toxin DUF815 PF05673.13 EQB60503.1 - 0.097 11.8 0.1 0.12 11.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 EQB60503.1 - 1.2 9.1 4.5 2.7 8.0 0.2 2.7 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit AAA_2 PF07724.14 EQB60504.1 - 2e-40 138.7 0.0 4.6e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EQB60504.1 - 4.1e-26 90.9 0.9 4.1e-26 90.9 0.9 2.3 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EQB60504.1 - 2.1e-12 46.9 1.9 7.7e-12 45.1 0.1 3.0 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EQB60504.1 - 1.4e-11 44.6 0.0 4.7e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EQB60504.1 - 7.7e-10 39.3 0.0 2.1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EQB60504.1 - 6.7e-06 26.6 0.0 0.013 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Sigma54_activat PF00158.26 EQB60504.1 - 1.7e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EQB60504.1 - 3.6e-05 23.2 0.6 0.077 12.4 0.0 2.9 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EQB60504.1 - 0.00023 20.9 0.0 0.00091 19.0 0.0 2.0 2 1 0 2 2 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EQB60504.1 - 0.0011 19.1 1.5 0.047 13.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EQB60504.1 - 0.0016 18.2 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EQB60504.1 - 0.0027 17.0 0.0 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 EQB60504.1 - 0.0035 17.6 0.3 0.086 13.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EQB60504.1 - 0.0072 16.9 0.0 0.039 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 EQB60504.1 - 0.013 15.2 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit DUF87 PF01935.17 EQB60504.1 - 0.016 15.3 0.1 0.016 15.3 0.1 3.0 2 1 1 3 3 3 0 Helicase HerA, central domain AAA_7 PF12775.7 EQB60504.1 - 0.018 14.6 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 EQB60504.1 - 0.018 15.1 0.2 0.082 12.9 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MAD PF05557.13 EQB60504.1 - 0.019 13.3 10.6 0.029 12.8 10.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ParA PF10609.9 EQB60504.1 - 0.049 13.1 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase RNA_helicase PF00910.22 EQB60504.1 - 0.076 13.4 0.6 0.5 10.8 0.0 2.5 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 EQB60504.1 - 0.083 12.6 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EQB60504.1 - 0.12 12.7 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EQB60504.1 - 0.13 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EQB60504.1 - 0.23 12.0 0.9 0.57 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter S-AdoMet_synt_M PF02772.16 EQB60507.1 - 0.22 11.8 1.5 0.39 11.0 0.3 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain WD40 PF00400.32 EQB60508.1 - 8.9e-12 45.3 0.7 0.82 10.6 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.6 EQB60508.1 - 7.1e-05 22.8 1.6 0.45 10.6 0.3 3.0 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EQB60508.1 - 8.8e-05 22.7 0.0 1 9.7 0.0 3.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain GTP_EFTU PF00009.27 EQB60509.1 - 5.1e-59 199.1 0.1 9.3e-59 198.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EQB60509.1 - 8.9e-11 42.0 0.0 1.9e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EQB60509.1 - 3.9e-09 36.5 0.0 1.2e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EQB60509.1 - 7.8e-05 22.7 0.2 0.0002 21.4 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase CBFD_NFYB_HMF PF00808.23 EQB60510.1 - 2.8e-07 30.7 0.1 3.3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3527 PF12043.8 EQB60510.1 - 0.059 12.9 0.3 0.056 13.0 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Surp PF01805.20 EQB60510.1 - 0.059 13.4 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Surp module PSP PF04046.16 EQB60512.1 - 5e-20 71.1 0.6 1.1e-19 70.0 0.3 1.7 2 0 0 2 2 2 1 PSP DUF382 PF04037.13 EQB60512.1 - 8.1e-11 42.2 0.6 8.1e-11 42.2 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) Pkinase PF00069.25 EQB60513.1 - 1.7e-45 155.5 1.5 1.9e-45 155.3 1.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60513.1 - 1.7e-32 112.7 0.2 1.9e-32 112.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EQB60513.1 - 1.9e-06 26.9 0.1 1.7e-05 23.8 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EQB60513.1 - 0.0017 18.0 0.2 0.36 10.4 0.2 2.7 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 MTS_N PF08468.11 EQB60513.1 - 0.032 14.3 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal Cation_efflux PF01545.21 EQB60514.1 - 3.5e-36 124.8 11.2 4.1e-36 124.6 11.2 1.0 1 0 0 1 1 1 1 Cation efflux family GtrA PF04138.14 EQB60514.1 - 0.022 15.0 7.0 0.043 14.1 7.0 1.4 1 1 0 1 1 1 0 GtrA-like protein Proton_antipo_C PF01010.19 EQB60514.1 - 0.023 14.3 0.4 0.41 10.2 0.4 2.1 1 1 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus COX2_TM PF02790.15 EQB60514.1 - 0.27 11.4 3.7 0.35 11.1 0.8 2.1 1 1 2 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain DUF2975 PF11188.8 EQB60514.1 - 0.61 10.0 5.8 0.26 11.2 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF2104 PF09877.9 EQB60514.1 - 0.79 10.0 8.2 8.4 6.7 3.5 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2104) UQ_con PF00179.26 EQB60515.1 - 4.2e-45 152.9 0.2 4.7e-45 152.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EQB60515.1 - 0.0094 15.7 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B FeS_assembly_P PF01883.19 EQB60516.1 - 5e-05 23.4 0.0 0.00075 19.6 0.0 2.3 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Ribosomal_L44 PF00935.19 EQB60517.1 - 2.6e-24 85.5 12.5 4.6e-24 84.7 12.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 NOB1_Zn_bind PF08772.11 EQB60517.1 - 0.31 11.2 9.2 0.074 13.2 1.4 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 EQB60517.1 - 0.41 10.1 5.9 6.3 6.4 1.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos PF00149.28 EQB60518.1 - 2.9e-09 37.7 0.0 3.4e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 EQB60519.1 - 4.9e-20 71.7 3.3 1.5e-16 60.3 0.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1345 PF07077.11 EQB60519.1 - 0.023 14.4 0.6 0.043 13.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Renin_r PF07850.14 EQB60519.1 - 3 8.5 4.2 11 6.7 1.0 2.4 2 0 0 2 2 2 0 Renin receptor-like protein VCBS PF13517.6 EQB60520.1 - 1.1 9.9 10.4 3.7 8.2 0.0 5.2 6 1 1 7 7 7 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Bromodomain PF00439.25 EQB60521.1 - 1.8e-22 79.2 0.4 2.6e-22 78.7 0.4 1.3 1 0 0 1 1 1 1 Bromodomain PAP2 PF01569.21 EQB60522.1 - 1.3e-25 89.8 0.1 1.5e-25 89.5 0.1 1.0 1 0 0 1 1 1 1 PAP2 superfamily AA_permease_2 PF13520.6 EQB60522.1 - 0.035 13.0 4.0 0.036 12.9 4.0 1.1 1 0 0 1 1 1 0 Amino acid permease PAP2_3 PF14378.6 EQB60522.1 - 0.051 13.3 0.4 0.51 10.0 0.6 2.1 2 0 0 2 2 2 0 PAP2 superfamily hnRNP_Q_AcD PF18360.1 EQB60526.1 - 0.013 15.4 0.3 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Metallophos PF00149.28 EQB60527.1 - 5e-14 53.3 2.1 5.4e-14 53.2 2.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EQB60527.1 - 4.6e-08 33.4 0.1 4.8e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PmrD PF11183.8 EQB60527.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Metallophos PF00149.28 EQB60529.1 - 1.2e-17 65.1 0.0 4.3e-17 63.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EQB60529.1 - 2.6e-10 40.7 0.3 2.9e-07 30.8 0.1 2.5 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain Rad60-SLD_2 PF13881.6 EQB60530.1 - 0.18 11.9 3.5 0.43 10.7 3.5 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Herpes_IR6 PF06307.12 EQB60530.1 - 0.26 10.8 4.0 16 4.9 0.4 3.5 1 1 3 4 4 4 0 Herpesvirus IR6 protein UPF0239 PF06783.11 EQB60531.1 - 0.32 11.2 3.2 0.2 11.9 1.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) TraG_N PF07916.11 EQB60533.1 - 1.6e-06 27.3 3.2 2e-06 27.0 3.2 1.0 1 0 0 1 1 1 1 TraG-like protein, N-terminal region DUF2207 PF09972.9 EQB60533.1 - 1.3 7.7 16.9 0.021 13.6 6.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Tmemb_9 PF05434.11 EQB60534.1 - 0.0011 18.8 2.6 0.0029 17.5 2.6 1.7 1 0 0 1 1 1 1 TMEM9 EVI2A PF05399.11 EQB60534.1 - 0.0029 17.3 5.0 0.0029 17.3 5.0 1.6 1 1 1 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) Shisa PF13908.6 EQB60534.1 - 0.4 10.9 0.9 0.67 10.2 0.6 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TraF PF13728.6 EQB60535.1 - 0.074 12.9 0.1 0.82 9.4 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF3909 PF13077.6 EQB60538.1 - 0.022 14.9 0.1 0.046 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) DUF2996 PF11210.8 EQB60538.1 - 0.046 14.2 2.2 0.46 10.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2996) BsuBI_PstI_RE PF06616.11 EQB60539.1 - 0.075 12.3 0.7 0.45 9.8 0.2 2.1 1 1 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain FBA_3 PF08268.12 EQB60542.1 - 0.11 12.5 6.4 0.02 14.8 2.7 1.8 2 1 0 2 2 2 0 F-box associated domain Fe_hyd_SSU PF02256.17 EQB60543.1 - 0.00062 19.8 1.1 0.0012 18.8 1.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Phage_Gp23 PF10669.9 EQB60544.1 - 0.00065 20.0 5.6 0.5 10.7 0.1 2.7 2 1 0 2 2 2 2 Protein gp23 (Bacteriophage A118) Cu PF17563.2 EQB60544.1 - 2 8.7 6.3 5 7.4 6.3 1.7 1 0 0 1 1 1 0 Cupiennin DUF5358 PF17311.2 EQB60545.1 - 0.0032 17.5 0.9 0.0032 17.5 0.9 3.4 2 1 1 3 3 3 2 Family of unknown function (DUF5358) AAA PF00004.29 EQB60547.1 - 1.3e-40 138.9 0.0 2.4e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EQB60547.1 - 7.3e-11 41.7 0.3 1.4e-10 40.8 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EQB60547.1 - 9e-09 35.2 0.0 1.8e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain DUF815 PF05673.13 EQB60547.1 - 2e-05 23.9 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EQB60547.1 - 5e-05 23.6 0.6 0.02 15.2 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EQB60547.1 - 9.3e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EQB60547.1 - 0.00024 20.9 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EQB60547.1 - 0.0006 19.8 0.4 0.0033 17.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 EQB60547.1 - 0.00065 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 EQB60547.1 - 0.0012 19.3 0.2 0.019 15.3 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EQB60547.1 - 0.0051 17.0 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EQB60547.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EQB60547.1 - 0.02 15.4 0.0 0.047 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EQB60547.1 - 0.023 14.7 0.1 0.096 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EQB60547.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EQB60547.1 - 0.038 13.2 0.2 0.084 12.1 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain Urm1 PF09138.11 EQB60547.1 - 0.055 13.8 0.1 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 Urm1 (Ubiquitin related modifier) NB-ARC PF00931.22 EQB60547.1 - 0.1 11.7 0.1 0.71 9.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 EQB60547.1 - 0.13 11.7 0.3 0.96 8.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 EQB60547.1 - 0.2 11.2 0.5 2.6 7.6 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 EQB60547.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0086 PF01868.16 EQB60548.1 - 0.00011 22.0 0.9 0.0011 18.9 0.9 2.1 1 1 0 1 1 1 1 Domain of unknown function UPF0086 PIP5K PF01504.18 EQB60549.1 - 7e-40 137.0 16.3 1.9e-29 102.7 11.2 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase E1_FCCH PF16190.5 EQB60549.1 - 0.15 12.3 2.6 1.4 9.2 0.2 3.1 2 1 1 3 3 3 0 Ubiquitin-activating enzyme E1 FCCH domain Peripla_BP_7 PF18610.1 EQB60551.1 - 0.049 13.8 0.3 0.049 13.8 0.3 2.5 2 1 0 2 2 2 0 Periplasmic binding protein domain ARGLU PF15346.6 EQB60552.1 - 0.0064 16.4 9.8 0.0079 16.1 9.8 1.0 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 SID-1_RNA_chan PF13965.6 EQB60552.1 - 0.031 12.7 4.0 0.04 12.3 4.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 EQB60552.1 - 0.033 14.2 3.6 0.044 13.8 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 EQB60552.1 - 0.049 14.6 0.3 0.049 14.6 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF1899 PF08953.11 EQB60552.1 - 0.058 13.3 0.3 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1899) Peptidase_S49_N PF08496.10 EQB60552.1 - 0.11 12.5 10.9 0.66 10.0 10.9 1.9 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF21 PF01595.20 EQB60552.1 - 0.16 11.7 0.2 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain CoxIIa PF08113.11 EQB60552.1 - 0.79 9.6 4.4 1.1 9.1 4.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family Vpu PF00558.19 EQB60552.1 - 1.5 8.7 4.1 0.81 9.5 0.3 2.1 1 1 1 2 2 2 0 Vpu protein O-antigen_lig PF13425.6 EQB60552.1 - 1.8 7.2 4.6 2 7.1 4.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein OATP PF03137.20 EQB60552.1 - 4 5.6 4.7 8.8 4.5 4.7 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CLN3 PF02487.17 EQB60552.1 - 5.3 6.0 6.9 10 5.1 6.9 1.5 1 1 0 1 1 1 0 CLN3 protein Ribosomal_L31e PF01198.19 EQB60553.1 - 2.7e-15 56.4 4.0 3.5e-15 56.0 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MutS_I PF01624.20 EQB60553.1 - 0.027 14.7 0.3 0.035 14.4 0.3 1.2 1 0 0 1 1 1 0 MutS domain I DUF682 PF05081.12 EQB60554.1 - 0.014 15.1 0.7 0.018 14.8 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF682) MSA-2c PF12238.8 EQB60554.1 - 0.89 9.5 2.7 0.96 9.4 2.7 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c LRR_8 PF13855.6 EQB60555.1 - 1e-26 92.5 56.3 5.3e-06 26.1 3.2 7.5 4 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EQB60555.1 - 1.5e-25 88.8 60.3 0.00012 22.4 1.3 6.7 2 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_3 PF07725.12 EQB60555.1 - 4.4 7.3 13.0 87 3.2 0.0 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat NDUF_B4 PF07225.12 EQB60556.1 - 0.00067 19.5 0.6 0.0014 18.5 0.6 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GILT PF03227.16 EQB60556.1 - 0.0073 16.6 0.3 0.017 15.4 0.3 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Ribosomal_S13_N PF08069.12 EQB60557.1 - 0.15 12.1 0.2 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Utp14 PF04615.13 EQB60558.1 - 2.9e-16 59.3 23.0 2.6e-14 52.8 1.9 2.2 1 1 1 2 2 2 2 Utp14 protein ATPgrasp_YheCD PF14398.6 EQB60558.1 - 0.0032 16.8 4.2 0.016 14.4 2.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp Presenilin PF01080.17 EQB60558.1 - 4.9 5.8 4.8 6.5 5.4 4.8 1.1 1 0 0 1 1 1 0 Presenilin EIF_2_alpha PF07541.12 EQB60560.1 - 7.7e-19 67.9 0.1 1.7e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EQB60560.1 - 2.1e-08 34.4 0.7 3.9e-08 33.5 0.2 1.7 2 0 0 2 2 2 1 S1 RNA binding domain E1_UFD PF09358.10 EQB60560.1 - 0.034 14.8 2.8 0.14 12.9 0.9 3.0 3 1 0 3 3 3 0 Ubiquitin fold domain TERF2_RBM PF16772.5 EQB60560.1 - 0.036 13.5 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif S-methyl_trans PF02574.16 EQB60560.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase Pkinase PF00069.25 EQB60561.1 - 2.9e-18 66.2 0.0 3.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60561.1 - 1.5e-06 27.7 0.0 3.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SPASM PF13186.6 EQB60561.1 - 0.13 12.7 1.3 0.69 10.5 0.2 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Sec1 PF00995.23 EQB60563.1 - 4.1e-67 227.7 18.9 4.9e-67 227.5 18.9 1.1 1 0 0 1 1 1 1 Sec1 family P16-Arc PF04699.14 EQB60563.1 - 0.048 14.1 5.5 0.093 13.2 0.9 2.5 2 1 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) RE_R_Pab1 PF09522.10 EQB60563.1 - 0.059 13.5 0.4 14 5.8 0.0 2.9 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease PP_kinase_N PF13089.6 EQB60563.1 - 0.4 11.0 2.8 14 6.0 0.1 2.7 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain Haspin_kinase PF12330.8 EQB60564.1 - 1.6e-26 93.1 6.2 1.6e-26 93.1 6.2 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EQB60564.1 - 0.00039 19.3 0.0 0.00041 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EQB60565.1 - 8.1e-27 94.2 1.6 9.4e-27 94.0 1.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60565.1 - 4.8e-17 62.1 0.3 5.9e-17 61.8 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EQB60565.1 - 2.9e-11 42.8 0.1 3.8e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EQB60565.1 - 1.5e-06 28.3 0.0 0.00085 19.3 0.1 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EQB60565.1 - 0.0055 16.1 0.5 0.017 14.5 0.5 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EQB60565.1 - 0.037 13.4 0.1 0.057 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_UL20 PF04544.12 EQB60565.1 - 0.13 12.6 0.3 1 9.7 0.2 1.9 1 1 1 2 2 2 0 Herpesvirus egress protein UL20 PCI PF01399.27 EQB60566.1 - 3.3e-05 24.3 9.5 3.3e-05 24.3 9.5 2.3 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EQB60566.1 - 0.043 13.9 0.4 0.15 12.2 0.4 2.0 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain ThiF PF00899.21 EQB60567.1 - 4.9e-79 265.1 0.0 1.6e-51 175.0 0.0 2.9 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EQB60567.1 - 3.4e-40 138.6 2.8 3.3e-39 135.3 2.8 2.2 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EQB60567.1 - 0.00023 21.8 0.4 0.00084 20.0 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EQB60567.1 - 0.00039 20.5 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 EQB60567.1 - 0.0017 18.4 1.3 2.7 8.1 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DUF2001 PF09393.10 EQB60567.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Phage tail tube protein NAD_binding_7 PF13241.6 EQB60567.1 - 0.081 13.4 0.1 26 5.3 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ThiF PF00899.21 EQB60568.1 - 7.9e-34 117.1 0.2 1.2e-29 103.4 0.3 2.1 1 1 1 2 2 2 2 ThiF family E1_4HB PF16191.5 EQB60568.1 - 0.0001 22.4 0.2 0.00028 21.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle LRR_8 PF13855.6 EQB60570.1 - 2e-30 104.3 75.5 8.7e-11 41.4 5.8 8.0 4 3 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EQB60570.1 - 3.1e-25 87.8 100.3 1.4e-06 28.5 3.9 9.8 7 2 3 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60570.1 - 4.6e-07 29.5 41.9 9.6e-05 21.9 8.6 4.5 1 1 3 4 4 4 3 Leucine-rich repeat RsmF_methylt_CI PF17126.5 EQB60570.1 - 0.072 13.1 1.2 55 3.9 0.0 5.0 4 2 1 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain TSC22 PF01166.18 EQB60571.1 - 3.8 7.9 5.8 9.1 6.7 0.3 2.7 1 1 2 3 3 3 0 TSC-22/dip/bun family ssDBP_DBD PF18361.1 EQB60573.1 - 0.018 15.2 1.3 0.043 14.0 1.3 1.6 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Thioredoxin_13 PF18401.1 EQB60574.1 - 0.034 14.0 0.7 0.054 13.4 0.3 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain HN PF00423.19 EQB60574.1 - 0.25 10.1 8.2 0.29 9.9 8.2 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase MRF_C2 PF13888.6 EQB60575.1 - 2.9 7.8 11.3 2.2 8.2 2.0 3.1 1 1 2 3 3 3 0 Myelin gene regulatory factor C-terminal domain 2 AAA PF00004.29 EQB60576.1 - 1.3e-45 155.0 0.0 4.2e-45 153.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EQB60576.1 - 2.4e-10 40.0 0.1 5.2e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EQB60576.1 - 2.7e-08 33.6 0.1 5.6e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EQB60576.1 - 7.7e-08 32.6 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EQB60576.1 - 7.1e-07 29.3 0.0 3.7e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EQB60576.1 - 1.6e-06 28.6 0.2 6.5e-05 23.4 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EQB60576.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EQB60576.1 - 9.5e-05 21.8 0.9 0.0065 15.8 0.0 2.6 3 0 0 3 3 3 1 KaiC AAA_22 PF13401.6 EQB60576.1 - 0.00017 21.8 5.3 0.012 15.9 0.1 2.9 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 EQB60576.1 - 0.00036 20.6 0.3 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EQB60576.1 - 0.00066 19.8 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EQB60576.1 - 0.00083 18.7 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EQB60576.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EQB60576.1 - 0.003 17.4 0.0 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EQB60576.1 - 0.0039 17.7 0.0 0.0085 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EQB60576.1 - 0.0045 16.5 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein TsaE PF02367.17 EQB60576.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EQB60576.1 - 0.0081 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EQB60576.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EQB60576.1 - 0.012 15.3 0.0 0.074 12.7 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 EQB60576.1 - 0.013 15.9 0.2 0.42 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EQB60576.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EQB60576.1 - 0.014 15.2 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EQB60576.1 - 0.026 14.9 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EQB60576.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EQB60576.1 - 0.031 14.8 0.5 0.68 10.5 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 EQB60576.1 - 0.044 13.4 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EQB60576.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EQB60576.1 - 0.07 12.9 0.3 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EQB60576.1 - 0.073 12.3 0.2 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Prot_ATP_OB_N PF17758.1 EQB60576.1 - 0.12 12.0 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 EQB60576.1 - 0.13 12.2 0.0 0.42 10.5 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_19 PF13245.6 EQB60576.1 - 0.16 12.3 0.5 0.44 10.9 0.1 1.9 2 0 0 2 2 1 0 AAA domain DivIC PF04977.15 EQB60576.1 - 0.86 9.4 6.0 0.77 9.6 4.3 1.7 2 0 0 2 2 1 0 Septum formation initiator DUF2316 PF10078.9 EQB60577.1 - 1.1 9.5 7.6 0.46 10.7 0.8 2.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Ras PF00071.22 EQB60580.1 - 9.4e-42 142.4 0.1 1.2e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB60580.1 - 3.5e-30 104.7 0.1 6.5e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB60580.1 - 3.6e-11 42.8 0.0 4.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EQB60580.1 - 2.4e-08 34.0 0.0 3.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EQB60580.1 - 3.3e-07 30.4 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EQB60580.1 - 0.00013 21.6 0.7 0.0046 16.5 0.7 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EQB60580.1 - 0.00037 19.8 5.8 1.5 7.9 3.2 3.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EQB60580.1 - 0.0016 17.8 0.0 0.0026 17.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EQB60580.1 - 0.0027 17.2 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 EQB60580.1 - 0.003 16.7 0.4 0.0049 16.0 0.4 1.6 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EQB60580.1 - 0.005 16.2 0.4 0.035 13.4 0.0 2.0 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 EQB60580.1 - 0.0055 16.4 0.2 0.01 15.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EQB60580.1 - 0.0073 16.2 0.1 0.017 15.0 0.1 1.5 1 1 0 1 1 1 1 NTPase Pox_A32 PF04665.12 EQB60580.1 - 0.036 13.5 0.2 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein TsaE PF02367.17 EQB60580.1 - 0.037 14.0 0.1 0.054 13.5 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EQB60580.1 - 0.063 13.6 0.1 0.19 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EQB60580.1 - 0.066 12.4 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 EQB60580.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EQB60580.1 - 0.078 12.8 0.3 5.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF4981 PF16353.5 EQB60580.1 - 0.082 13.4 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) SRPRB PF09439.10 EQB60580.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 EQB60580.1 - 0.13 11.8 0.1 4 7.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4715 PF15835.5 EQB60580.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) AAA_18 PF13238.6 EQB60580.1 - 0.23 12.0 1.3 0.63 10.6 0.2 2.3 2 1 0 2 2 2 0 AAA domain mRNA_triPase PF02940.15 EQB60581.1 - 1.8e-20 73.6 5.6 2.8e-11 43.6 2.1 2.1 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain MCR_D PF02505.14 EQB60582.1 - 0.047 13.5 0.1 0.098 12.5 0.0 1.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D Xan_ur_permease PF00860.20 EQB60583.1 - 0.0085 14.8 0.1 0.013 14.2 0.1 1.4 1 0 0 1 1 1 1 Permease family RabGAP-TBC PF00566.18 EQB60584.1 - 1.9e-20 73.4 14.6 2.8e-20 72.9 14.6 1.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TP_methylase PF00590.20 EQB60585.1 - 6.6e-14 52.4 0.0 8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases SNO PF01174.19 EQB60585.1 - 0.02 14.7 0.3 0.09 12.6 0.1 1.9 2 0 0 2 2 2 0 SNO glutamine amidotransferase family TBCA PF02970.16 EQB60586.1 - 0.00039 20.7 2.0 0.00045 20.5 2.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A zf-C4H2 PF10146.9 EQB60586.1 - 0.32 11.3 1.9 0.37 11.1 1.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein polyprenyl_synt PF00348.17 EQB60587.1 - 1.8e-09 37.1 1.3 2e-09 36.9 1.3 1.2 1 1 0 1 1 1 1 Polyprenyl synthetase Helicase_C PF00271.31 EQB60589.1 - 5 7.5 12.0 0.33 11.3 2.6 2.8 1 1 1 3 3 3 0 Helicase conserved C-terminal domain BsuBI_PstI_RE PF06616.11 EQB60590.1 - 0.083 12.2 0.9 0.86 8.9 0.2 2.0 1 1 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain LRR_8 PF13855.6 EQB60591.1 - 2.9e-24 84.6 60.0 6.5e-08 32.2 8.0 5.0 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EQB60591.1 - 3.5e-20 71.8 79.4 4.6e-05 23.7 7.5 6.3 1 1 7 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60591.1 - 0.0074 15.8 36.4 0.048 13.2 12.9 3.8 1 1 3 4 4 4 3 Leucine-rich repeat YdiH PF15930.5 EQB60591.1 - 0.041 14.1 0.7 4.6 7.5 0.1 3.4 2 1 1 3 3 3 0 Domain of unknown function LRR_2 PF07723.13 EQB60591.1 - 0.069 13.8 0.9 0.069 13.8 0.9 6.1 8 2 1 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 EQB60591.1 - 1.1 9.5 53.5 1.1 9.5 0.8 9.6 10 0 0 10 10 10 0 Leucine Rich repeat LAGLIDADG_WhiA PF14527.6 EQB60592.1 - 2.2 8.4 5.1 1 9.5 1.1 2.6 2 1 0 2 2 2 0 WhiA LAGLIDADG-like domain Glyco_hydro_106 PF17132.4 EQB60593.1 - 0.035 12.4 0.2 0.058 11.7 0.2 1.3 1 0 0 1 1 1 0 alpha-L-rhamnosidase Brix PF04427.18 EQB60593.1 - 2.9 7.9 8.4 6.1 6.9 0.7 2.4 1 1 1 2 2 2 0 Brix domain CooT PF10133.9 EQB60594.1 - 0.14 12.5 3.0 0.33 11.3 0.1 2.9 3 0 0 3 3 3 0 CO dehydrogenase accessory protein CooT CDC37_N PF03234.14 EQB60596.1 - 5.7e-09 37.0 10.3 5.7e-09 37.0 10.3 2.0 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding Cas_Csy2 PF09614.10 EQB60596.1 - 0.053 12.9 1.1 0.27 10.5 0.2 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csy2) T6PP_N PF18572.1 EQB60596.1 - 6.2 6.7 14.5 0.94 9.4 7.4 2.4 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HSP90 PF00183.18 EQB60597.1 - 8.1e-130 434.1 32.6 1.1e-129 433.7 32.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EQB60597.1 - 3.9e-09 36.4 0.1 3.9e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EQB60597.1 - 8.9e-09 35.9 0.1 1.9e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Fe_hyd_SSU PF02256.17 EQB60597.1 - 0.027 14.5 0.2 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Iron hydrogenase small subunit Helicase_C_2 PF13307.6 EQB60598.1 - 1.7e-25 90.2 0.0 3.5e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain Maf1 PF09174.10 EQB60598.1 - 0.0074 16.5 1.3 0.015 15.5 1.3 1.5 1 0 0 1 1 1 1 Maf1 regulator Thg1 PF04446.12 EQB60598.1 - 8.2 6.5 6.6 1.9 8.5 0.9 2.5 2 1 1 3 3 3 0 tRNAHis guanylyltransferase ResIII PF04851.15 EQB60599.1 - 0.0045 17.0 0.2 0.0086 16.1 0.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EQB60599.1 - 0.067 12.9 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase EnY2 PF10163.9 EQB60602.1 - 8e-07 29.3 1.6 9.1e-07 29.2 1.6 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 CNP_C_terminal PF17839.1 EQB60602.1 - 0.019 15.7 1.3 0.024 15.4 0.9 1.4 1 1 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase CdiI_2 PF18593.1 EQB60602.1 - 0.068 13.8 1.2 3.9 8.2 0.3 2.1 2 0 0 2 2 2 0 CdiI immunity protein CH_2 PF06294.11 EQB60602.1 - 0.071 13.2 1.0 0.099 12.8 1.0 1.3 1 1 0 1 1 1 0 CH-like domain in sperm protein MOZART2 PF12926.7 EQB60602.1 - 0.27 10.9 1.0 0.48 10.1 0.3 1.8 1 1 1 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF3837 PF12939.7 EQB60602.1 - 2.1 8.8 7.2 7.4 7.0 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) PSP1 PF04468.12 EQB60603.1 - 4.3e-26 91.0 5.4 4.3e-26 91.0 5.4 2.1 2 1 0 2 2 2 1 PSP1 C-terminal conserved region ING PF12998.7 EQB60603.1 - 0.055 14.1 0.2 0.055 14.1 0.2 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding LRR_8 PF13855.6 EQB60604.1 - 5.2e-19 67.8 29.1 9.4e-08 31.7 6.2 5.7 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EQB60604.1 - 1.1e-17 63.8 38.5 1.1e-05 25.6 5.0 5.5 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60604.1 - 0.00045 19.8 20.5 0.024 14.1 8.0 2.8 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EQB60604.1 - 0.13 12.4 29.0 1.7 8.9 0.6 7.4 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 EQB60604.1 - 1.4 9.7 35.8 0.36 11.6 0.5 8.3 8 1 0 8 8 8 0 Leucine Rich Repeat tRNA-synt_2 PF00152.20 EQB60605.1 - 3.8e-79 266.0 0.4 5.7e-79 265.4 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EQB60605.1 - 8.9e-09 35.2 0.3 1.7e-08 34.3 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EQB60605.1 - 1.4e-07 31.2 0.0 0.0035 16.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Fucokinase PF07959.12 EQB60606.1 - 2.5e-06 26.7 1.0 8.1e-06 25.0 0.5 1.8 2 0 0 2 2 2 1 L-fucokinase Hexapep PF00132.24 EQB60606.1 - 0.00068 19.3 17.3 0.0068 16.1 3.8 3.6 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) PUA PF01472.20 EQB60607.1 - 2.4e-09 37.0 0.1 3.7e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 EQB60607.1 - 0.013 16.2 0.9 0.057 14.1 0.9 2.0 1 1 0 1 1 1 0 Pre-PUA-like domain Peptidase_M48 PF01435.18 EQB60608.1 - 1.3e-10 41.4 0.0 1.7e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Proteasome PF00227.26 EQB60609.1 - 2.2e-27 95.8 0.0 2.7e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Nop52 PF05997.12 EQB60610.1 - 0.021 14.6 1.1 0.078 12.8 0.1 2.0 1 1 1 2 2 2 0 Nucleolar protein,Nop52 TACI-CRD2 PF09305.10 EQB60610.1 - 0.05 13.6 0.3 8.5 6.5 0.1 2.5 2 0 0 2 2 2 0 TACI, cysteine-rich domain Symplekin_C PF12295.8 EQB60611.1 - 4.2e-14 53.1 0.2 8.7e-14 52.0 0.2 1.5 1 1 0 1 1 1 1 Symplekin tight junction protein C terminal MecA_N PF05223.11 EQB60612.1 - 0.011 16.0 0.7 0.023 15.0 0.2 1.8 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Sec6 PF06046.13 EQB60613.1 - 2.8e-38 131.7 9.5 3.4e-38 131.4 9.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 SAM_KSR1 PF13543.6 EQB60613.1 - 0.063 13.4 3.7 0.072 13.2 0.7 2.2 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Rep_N PF08724.10 EQB60613.1 - 0.88 9.3 7.4 1.8 8.3 2.9 2.8 3 0 0 3 3 3 0 Rep protein catalytic domain like Erv26 PF04148.13 EQB60614.1 - 8.1e-14 51.9 12.4 2.2e-12 47.2 12.4 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 SHQ1 PF04925.15 EQB60614.1 - 0.096 12.2 5.4 2.5 7.7 1.4 2.0 1 1 1 2 2 2 0 SHQ1 protein GDI PF00996.18 EQB60615.1 - 1.4e-12 46.9 10.3 4.1e-08 32.2 4.8 2.1 1 1 1 2 2 2 2 GDP dissociation inhibitor DUF87 PF01935.17 EQB60615.1 - 0.015 15.4 4.2 0.032 14.3 4.2 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain Binary_toxB_3 PF17476.2 EQB60615.1 - 0.94 9.7 4.5 2.9 8.1 2.0 2.9 1 1 1 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 PIN_4 PF13638.6 EQB60616.1 - 7.6e-13 48.9 3.7 1.3e-12 48.1 3.7 1.3 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 EQB60616.1 - 0.0035 17.6 1.1 0.027 14.8 1.1 2.1 1 1 0 1 1 1 1 PIN like domain rve PF00665.26 EQB60617.1 - 1e-13 51.5 0.0 2.8e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EQB60617.1 - 7.3e-13 48.4 2.4 5.1e-12 45.7 0.5 3.2 3 0 0 3 3 3 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 EQB60617.1 - 3.1e-08 34.1 0.0 9.2e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 EQB60617.1 - 4.7e-08 32.9 0.1 1.4e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EQB60617.1 - 3.6e-07 30.0 1.6 4.1e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 EQB60617.1 - 2.2e-06 27.3 0.2 6.8e-06 25.7 0.2 1.9 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 EQB60617.1 - 3e-06 27.8 0.0 7.8e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 EQB60617.1 - 1.1e-05 25.5 1.6 5.4e-05 23.3 0.4 2.7 2 0 0 2 2 2 1 H2C2 zinc finger RVP PF00077.20 EQB60617.1 - 3.7e-05 24.0 0.1 8.6e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease MLVIN_C PF18697.1 EQB60617.1 - 0.0043 17.1 0.2 0.013 15.6 0.2 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain OTCace_N PF02729.21 EQB60617.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain rve_3 PF13683.6 EQB60617.1 - 0.025 14.4 0.0 0.077 12.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain DUF1758 PF05585.12 EQB60617.1 - 0.063 13.1 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-H3C2 PF16721.5 EQB60617.1 - 0.077 13.4 0.7 0.37 11.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding DUF4976 PF16347.5 EQB60617.1 - 4.4 7.6 8.1 0.59 10.4 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Peptidase_S8 PF00082.22 EQB60618.1 - 2.6e-08 33.5 4.5 1.1e-07 31.4 4.5 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EQB60618.1 - 2.3e-06 28.2 0.2 5e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EQB60619.1 - 2e-18 66.7 0.0 2.3e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Subtilase family Cyclin_N PF00134.23 EQB60622.1 - 0.025 14.3 0.4 0.1 12.3 0.0 2.1 3 0 0 3 3 3 0 Cyclin, N-terminal domain Enolase_C PF00113.22 EQB60624.1 - 1e-92 310.5 0.0 1.3e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EQB60624.1 - 2.4e-35 121.5 0.0 4.6e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EQB60624.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like CorA PF01544.18 EQB60625.1 - 5.4e-15 55.5 2.9 7e-15 55.1 2.9 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA_11 PF13086.6 EQB60626.1 - 1.1e-07 32.0 8.6 1.2e-06 28.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF5599 PF18141.1 EQB60626.1 - 8.4e-06 25.9 0.0 2.3e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EQB60626.1 - 7.8e-05 22.5 0.1 0.00012 21.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EQB60626.1 - 0.00093 19.2 0.2 0.00093 19.2 0.2 2.8 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EQB60626.1 - 0.0017 17.8 0.1 0.0027 17.2 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 EQB60626.1 - 0.0029 18.0 0.2 0.0052 17.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EQB60626.1 - 0.0048 16.2 0.0 0.0048 16.2 0.0 2.3 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EQB60626.1 - 0.009 15.4 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA PF00004.29 EQB60626.1 - 0.048 14.1 0.1 0.097 13.1 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EQB60626.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 EQB60626.1 - 0.057 13.7 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 EQB60627.1 - 5e-53 179.7 0.0 7.6e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EQB60627.1 - 2.2e-27 96.5 0.0 4.1e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EQB60627.1 - 0.0033 17.2 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EQB60627.1 - 0.02 14.7 0.0 0.072 12.9 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EQB60627.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AroM PF07302.11 EQB60627.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 AroM protein Rad51 PF08423.11 EQB60630.1 - 8e-109 362.8 0.0 9.9e-109 362.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EQB60630.1 - 3.4e-11 43.1 0.0 5.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EQB60630.1 - 1.8e-05 24.4 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EQB60630.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 EQB60630.1 - 0.0087 15.2 0.5 0.23 10.6 0.1 2.3 2 0 0 2 2 2 1 PAXNEB protein ATPase PF06745.13 EQB60630.1 - 0.033 13.5 5.5 0.019 14.3 1.3 2.5 2 1 0 2 2 2 0 KaiC HHH_5 PF14520.6 EQB60630.1 - 0.063 13.9 0.4 0.23 12.1 0.7 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain Elong_Iki1 PF10483.9 EQB60630.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 PX PF00787.24 EQB60630.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 PX domain UQ_con PF00179.26 EQB60631.1 - 1.1e-35 122.3 0.1 1.7e-35 121.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EQB60631.1 - 0.11 12.8 0.3 0.32 11.3 0.1 1.8 2 0 0 2 2 2 0 RWD domain ETRAMP PF09716.10 EQB60632.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.1 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RNase_HII PF01351.18 EQB60634.1 - 0.18 11.6 1.6 0.26 11.1 0.3 1.8 1 1 1 2 2 2 0 Ribonuclease HII ORF6C PF10552.9 EQB60635.1 - 0.0077 16.3 1.2 0.0077 16.3 1.2 1.8 1 1 1 2 2 2 1 ORF6C domain LRR_8 PF13855.6 EQB60636.1 - 4.9e-34 115.9 84.4 6.7e-08 32.2 4.5 7.5 4 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EQB60636.1 - 5.1e-19 68.1 123.8 0.00022 21.6 12.6 9.7 5 1 6 12 12 12 10 Leucine Rich repeats (2 copies) HSP70 PF00012.20 EQB60639.1 - 7.9e-214 711.3 9.3 8.8e-214 711.1 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EQB60639.1 - 8.2e-22 77.4 0.3 4e-18 65.3 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EQB60639.1 - 0.00014 21.7 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EQB60639.1 - 0.00016 22.1 1.3 0.39 11.2 0.0 3.0 3 0 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EQB60639.1 - 0.0069 15.4 1.3 0.038 13.0 0.4 2.2 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain DNA_primase_lrg PF04104.14 EQB60639.1 - 0.009 15.4 0.3 0.009 15.4 0.3 1.8 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit BcrAD_BadFG PF01869.20 EQB60639.1 - 0.02 14.4 0.2 0.82 9.1 0.2 2.3 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family PA28_alpha PF02251.18 EQB60639.1 - 0.066 13.3 5.5 0.1 12.7 4.3 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit GlutR_dimer PF00745.20 EQB60639.1 - 0.07 13.6 0.3 0.33 11.4 0.1 2.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain ArfGap PF01412.18 EQB60640.1 - 7.1e-06 26.1 2.5 7.1e-06 26.1 2.5 2.3 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf MS_channel PF00924.18 EQB60640.1 - 0.017 14.7 1.7 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel SRP1_TIP1 PF00660.17 EQB60641.1 - 0.074 13.1 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Seripauperin and TIP1 family LRR_8 PF13855.6 EQB60642.1 - 5.5e-06 26.0 38.0 0.0095 15.7 1.9 5.8 5 0 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EQB60642.1 - 0.014 15.8 6.2 0.014 15.8 6.2 8.4 7 3 2 9 9 9 0 Leucine Rich repeats (2 copies) DUF3734 PF12536.8 EQB60643.1 - 0.03 14.7 0.2 0.047 14.0 0.2 1.2 1 0 0 1 1 1 0 Patatin phospholipase Kinesin PF00225.23 EQB60644.1 - 2.6e-59 200.8 1.2 2.6e-59 200.8 1.2 2.2 2 1 0 2 2 2 1 Kinesin motor domain HSBP1 PF06825.12 EQB60646.1 - 1.9 8.4 4.7 3.8 7.4 0.8 2.6 1 1 1 2 2 2 0 Heat shock factor binding protein 1 SMC_N PF02463.19 EQB60647.1 - 1.6e-08 34.3 6.5 1.6e-08 34.3 6.5 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain CENP-F_leu_zip PF10473.9 EQB60648.1 - 0.21 11.6 14.8 0.12 12.4 2.2 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EQB60648.1 - 1.2 9.6 13.4 5.2 7.6 0.5 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region UQ_con PF00179.26 EQB60649.1 - 4.9e-25 87.8 0.0 5.8e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ricin_B_lectin PF00652.22 EQB60650.1 - 0.031 14.5 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Baculo_LEF-10 PF07206.11 EQB60650.1 - 0.54 10.4 3.0 0.21 11.8 0.4 1.7 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) NAD_binding_1 PF00175.21 EQB60651.1 - 1.5e-12 48.1 0.0 3e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EQB60651.1 - 3.7e-06 27.2 2.2 3.5e-05 24.0 0.7 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EQB60651.1 - 0.01 16.2 0.1 0.077 13.4 0.0 2.3 2 1 1 3 3 3 0 Oxidoreductase FAD-binding domain Chitin_synth_2 PF03142.15 EQB60652.1 - 8.1e-199 661.6 15.8 1.3e-196 654.3 15.8 2.2 1 1 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EQB60652.1 - 8.1e-17 61.8 0.1 3.4e-16 59.7 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EQB60652.1 - 1.4e-14 54.5 0.0 7.8e-13 48.8 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EQB60652.1 - 4.6e-09 36.3 0.1 0.003 17.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EQB60652.1 - 4e-07 29.7 0.0 0.00014 21.4 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 21 Ribosomal_S8 PF00410.19 EQB60653.1 - 4.8e-14 52.4 0.0 6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 CRISPR_Cas9_WED PF18061.1 EQB60653.1 - 0.014 15.4 0.2 0.02 15.0 0.2 1.3 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain MarR PF01047.22 EQB60653.1 - 0.056 13.4 0.1 0.093 12.7 0.1 1.3 1 0 0 1 1 1 0 MarR family Rtt106 PF08512.12 EQB60654.1 - 5e-16 58.9 8.0 3.1e-15 56.3 0.0 3.5 3 1 1 4 4 4 2 Histone chaperone Rttp106-like POB3_N PF17292.2 EQB60654.1 - 3.7e-07 30.5 0.6 0.013 15.9 0.1 2.9 2 2 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 EQB60654.1 - 0.071 13.0 0.2 0.071 13.0 0.2 2.5 3 1 0 3 3 3 0 Structure-specific recognition protein (SSRP1) zf-C2H2_aberr PF17017.5 EQB60655.1 - 3.6e-06 27.2 16.1 0.00077 19.6 0.4 3.0 1 1 2 3 3 3 2 Aberrant zinc-finger zf_Hakai PF18408.1 EQB60655.1 - 8.5e-06 25.4 1.2 0.13 12.0 0.1 2.6 3 0 0 3 3 3 2 C2H2 Hakai zinc finger domain zf-C2H2 PF00096.26 EQB60655.1 - 1.5e-05 25.2 10.9 0.0048 17.3 0.5 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EQB60655.1 - 2e-05 25.0 7.3 0.04 14.7 0.7 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 EQB60655.1 - 0.0056 17.3 0.3 0.22 12.2 0.1 2.3 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-BED PF02892.15 EQB60655.1 - 0.047 13.7 6.5 0.49 10.5 2.1 2.4 2 0 0 2 2 2 0 BED zinc finger CHORD PF04968.12 EQB60655.1 - 0.3 11.8 6.1 2.8 8.7 0.8 2.5 2 0 0 2 2 2 0 CHORD Ski_Sno PF02437.17 EQB60656.1 - 0.0082 15.9 0.1 0.0093 15.7 0.1 1.2 1 0 0 1 1 1 1 SKI/SNO/DAC family Terminase_3 PF04466.13 EQB60657.1 - 0.013 15.1 5.7 0.014 14.9 5.7 1.1 1 0 0 1 1 1 0 Phage terminase large subunit HMMR_N PF15905.5 EQB60657.1 - 0.14 11.6 7.1 0.16 11.4 7.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF2227 PF09988.9 EQB60658.1 - 6.5 6.6 7.3 1.9 8.3 1.4 2.2 1 1 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) HSP70 PF00012.20 EQB60659.1 - 1.6e-18 66.2 1.8 6.3e-16 57.7 0.4 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EQB60659.1 - 3.6e-07 29.3 0.0 8.7e-07 28.1 0.0 1.5 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 EQB60659.1 - 0.0019 18.6 1.9 0.28 11.6 0.6 2.6 2 1 0 2 2 2 2 Cell division protein FtsA Synapsin_N PF10581.9 EQB60659.1 - 0.023 14.6 0.4 0.052 13.5 0.4 1.5 1 0 0 1 1 1 0 Synapsin N-terminal LRR_4 PF12799.7 EQB60661.1 - 2.7e-06 27.6 18.9 3.4e-05 24.1 8.6 5.2 4 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60661.1 - 5.6e-05 22.8 24.4 0.00044 20.0 8.1 3.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EQB60661.1 - 1.1 10.0 15.3 3.4 8.6 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat TraF PF13728.6 EQB60662.1 - 0.048 13.5 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Reprolysin_2 PF13574.6 EQB60665.1 - 0.82 9.5 3.0 5.6 6.8 0.2 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DHHC PF01529.20 EQB60666.1 - 3.1e-27 95.3 20.8 3.1e-27 95.3 20.8 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 EQB60667.1 - 3.1e-06 27.3 16.1 4.9e-06 26.7 16.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase NLRC4_HD PF17889.1 EQB60668.1 - 0.045 14.1 0.5 0.059 13.7 0.5 1.3 1 1 0 1 1 1 0 NLRC4 helical domain RVT_1 PF00078.27 EQB60669.1 - 1.6e-13 50.7 8.6 1.3e-10 41.2 1.0 5.1 5 1 1 6 6 6 2 Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD PF12009.8 EQB60669.1 - 5.4e-10 39.5 21.6 1.3e-07 31.8 5.0 4.0 2 1 1 3 3 3 2 Telomerase ribonucleoprotein complex - RNA binding domain RRM_4 PF10598.9 EQB60669.1 - 2.2 8.7 10.7 3 8.2 0.3 3.9 2 1 1 3 3 3 0 RNA recognition motif of the spliceosomal PrP8 eIF2A PF08662.11 EQB60671.1 - 3.9e-17 62.8 0.9 3.9e-17 62.8 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Metallophos PF00149.28 EQB60672.1 - 3e-20 73.6 0.0 3.9e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EQB60672.1 - 4.4e-17 62.2 1.2 1.1e-16 61.0 0.4 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain AAA_13 PF13166.6 EQB60673.1 - 0.0019 16.9 2.9 0.002 16.9 2.9 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran_CTD PF16326.5 EQB60673.1 - 0.017 15.4 3.0 0.23 11.7 1.1 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain PCRF PF03462.18 EQB60673.1 - 0.021 14.7 1.5 0.026 14.4 1.5 1.2 1 0 0 1 1 1 0 PCRF domain DUF4047 PF13256.6 EQB60673.1 - 0.023 14.9 0.8 0.044 14.0 0.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Snf7 PF03357.21 EQB60673.1 - 0.029 14.0 0.3 0.029 14.0 0.3 1.8 2 0 0 2 2 2 0 Snf7 DUF5093 PF17011.5 EQB60673.1 - 0.038 14.3 1.8 0.038 14.3 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) Fzo_mitofusin PF04799.13 EQB60673.1 - 0.13 11.8 2.7 5.7 6.5 0.1 2.3 1 1 1 2 2 2 0 fzo-like conserved region CCDC-167 PF15188.6 EQB60673.1 - 0.38 11.1 5.1 2.3 8.6 2.1 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 NPV_P10 PF05531.12 EQB60673.1 - 0.39 11.2 2.4 2.8 8.5 2.2 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein XPG_I PF00867.18 EQB60674.1 - 5.7e-19 68.3 1.7 3.1e-18 65.9 0.2 2.5 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EQB60674.1 - 3.3e-06 27.5 0.1 1e-05 25.9 0.1 1.9 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EQB60674.1 - 0.00023 21.7 0.1 0.00073 20.1 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold FeoB_Cyto PF17910.1 EQB60674.1 - 0.0073 16.8 0.2 0.018 15.6 0.2 1.7 1 0 0 1 1 1 1 FeoB cytosolic helical domain XPG_I_2 PF12813.7 EQB60674.1 - 0.049 13.1 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 XPG domain containing HHH_2 PF12826.7 EQB60674.1 - 0.065 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EQB60674.1 - 0.083 13.5 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Transposase_20 PF02371.16 EQB60674.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Hydrolase_3 PF08282.12 EQB60674.1 - 2 8.1 11.7 0.41 10.3 2.5 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Polysacc_deac_1 PF01522.21 EQB60675.1 - 1.8e-14 53.7 0.5 3.6e-14 52.7 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase NBD94 PF16830.5 EQB60675.1 - 0.27 11.7 1.9 20 5.7 0.0 2.6 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH CTP_transf_like PF01467.26 EQB60676.1 - 9e-16 58.4 0.3 5.5e-09 36.3 0.0 2.0 1 1 1 2 2 2 2 Cytidylyltransferase-like HEPN_RiboL-PSP PF18735.1 EQB60677.1 - 0.016 15.1 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 RiboL-PSP-HEPN Ribosomal_S10 PF00338.22 EQB60677.1 - 0.038 14.2 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e CS PF04969.16 EQB60678.1 - 4.7e-07 30.7 2.1 8.1e-07 30.0 2.1 1.4 1 0 0 1 1 1 1 CS domain Neur_chan_memb PF02932.16 EQB60678.1 - 0.18 11.8 1.0 0.18 11.9 1.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LKAAEAR PF15478.6 EQB60678.1 - 0.2 11.9 2.3 0.28 11.5 2.3 1.4 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif AAA_23 PF13476.6 EQB60678.1 - 0.27 11.7 12.7 0.37 11.3 12.7 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EQB60680.1 - 3.9e-96 318.5 0.0 7.1e-48 162.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EQB60680.1 - 6.6e-22 77.0 0.1 5.3e-10 38.9 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EQB60680.1 - 9e-15 54.8 0.0 1e-06 28.6 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EQB60680.1 - 4.3e-13 49.7 0.0 1.9e-06 28.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EQB60680.1 - 2.1e-12 47.7 0.3 0.0024 18.3 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EQB60680.1 - 1.1e-10 41.7 0.3 9.3e-05 22.4 0.1 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB60680.1 - 1.3e-10 41.7 1.6 0.027 14.7 0.0 4.8 3 2 3 6 6 5 2 AAA domain AAA_33 PF13671.6 EQB60680.1 - 1.8e-10 41.1 0.0 0.00016 21.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EQB60680.1 - 2.2e-09 37.0 0.0 0.00047 19.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EQB60680.1 - 2.3e-08 34.6 0.0 0.0015 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EQB60680.1 - 2.5e-08 34.3 0.0 0.013 15.9 0.0 3.7 4 0 0 4 4 2 2 RNA helicase Vps4_C PF09336.10 EQB60680.1 - 2.5e-08 33.8 3.2 1e-06 28.7 0.1 3.8 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 EQB60680.1 - 2.9e-08 33.8 0.0 0.0008 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EQB60680.1 - 2e-07 30.6 0.4 0.027 13.9 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EQB60680.1 - 2.1e-07 30.8 0.0 0.011 15.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Bac_DnaA PF00308.18 EQB60680.1 - 2.2e-07 30.9 0.0 0.00028 20.8 0.0 2.9 2 0 0 2 2 2 1 Bacterial dnaA protein ABC_tran PF00005.27 EQB60680.1 - 5.2e-07 30.3 0.0 0.07 13.6 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 EQB60680.1 - 1.3e-06 28.0 0.0 0.05 13.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 EQB60680.1 - 2.5e-06 27.6 0.4 0.03 14.3 0.1 3.3 2 2 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EQB60680.1 - 2.9e-06 27.8 0.3 0.036 14.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EQB60680.1 - 4.5e-06 26.5 0.1 0.0071 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EQB60680.1 - 7.8e-06 26.2 0.0 0.19 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EQB60680.1 - 1.7e-05 24.5 1.3 0.82 9.2 0.1 4.0 4 1 1 5 5 4 2 AAA domain Parvo_NS1 PF01057.17 EQB60680.1 - 2.5e-05 23.5 0.2 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 TsaE PF02367.17 EQB60680.1 - 4.1e-05 23.6 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC48_N PF02359.18 EQB60680.1 - 5.4e-05 23.3 0.0 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.12 EQB60680.1 - 6.4e-05 22.3 0.1 0.18 11.0 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 EQB60680.1 - 6.7e-05 22.9 0.4 0.42 10.5 0.0 3.4 3 1 1 4 4 3 2 NACHT domain Sigma54_activ_2 PF14532.6 EQB60680.1 - 0.00013 22.1 0.0 0.051 13.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 EQB60680.1 - 0.00017 21.4 0.0 0.66 9.7 0.0 3.4 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 EQB60680.1 - 0.00019 20.9 5.0 1.1 8.6 0.0 4.2 4 1 1 5 5 3 1 KaiC NB-ARC PF00931.22 EQB60680.1 - 0.00034 19.9 0.0 0.61 9.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.18 EQB60680.1 - 0.00054 19.8 0.0 0.45 10.2 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EQB60680.1 - 0.00073 18.9 0.0 0.31 10.2 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 EQB60680.1 - 0.00094 19.2 0.1 2.3 8.1 0.0 2.8 3 0 0 3 3 2 2 Rad17 P-loop domain DUF815 PF05673.13 EQB60680.1 - 0.0011 18.3 0.1 1.5 7.9 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PhoH PF02562.16 EQB60680.1 - 0.0012 18.3 0.2 0.99 8.8 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Cytidylate_kin2 PF13189.6 EQB60680.1 - 0.0015 18.7 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_3 PF07726.11 EQB60680.1 - 0.0022 17.9 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EQB60680.1 - 0.0042 17.0 0.9 5.1 7.0 0.0 3.8 2 1 1 4 4 3 0 NTPase AAA_19 PF13245.6 EQB60680.1 - 0.0064 16.8 0.7 3.9 7.8 0.1 3.0 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 EQB60680.1 - 0.011 15.6 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EQB60680.1 - 0.013 15.6 0.0 0.79 9.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.14 EQB60680.1 - 0.015 14.6 0.4 2 7.6 0.0 3.1 2 2 1 4 4 4 0 KAP family P-loop domain AAA_23 PF13476.6 EQB60680.1 - 0.04 14.4 1.9 13 6.3 0.1 3.2 3 1 0 3 3 2 0 AAA domain Zot PF05707.12 EQB60680.1 - 0.05 13.2 1.8 1.8 8.2 0.0 3.8 4 2 0 4 4 2 0 Zonular occludens toxin (Zot) PduV-EutP PF10662.9 EQB60680.1 - 0.055 13.2 0.0 11 5.7 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EQB60680.1 - 0.07 12.2 0.0 8.4 5.4 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 EQB60680.1 - 0.074 12.8 0.1 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 EQB60680.1 - 0.1 12.3 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase TniB PF05621.11 EQB60680.1 - 0.11 11.9 0.0 13 5.2 0.0 3.3 3 1 1 4 4 4 0 Bacterial TniB protein AAA_30 PF13604.6 EQB60680.1 - 0.14 11.9 0.6 11 5.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 EQB60680.1 - 0.19 12.0 2.3 23 5.2 0.0 3.6 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain WD40 PF00400.32 EQB60681.1 - 1.6e-25 88.8 18.4 8.6e-10 39.1 0.3 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB60681.1 - 1.7e-05 25.0 0.2 0.35 11.2 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 EQB60681.1 - 0.033 13.5 0.0 4.9 6.4 0.0 2.8 1 1 2 3 3 3 0 Minichromosome loss protein, Mcl1, middle region Frataxin_Cyay PF01491.16 EQB60682.1 - 1.5e-16 60.4 0.8 2e-16 60.0 0.8 1.2 1 0 0 1 1 1 1 Frataxin-like domain C1_1 PF00130.22 EQB60683.1 - 3e-11 43.0 3.8 6.2e-11 42.0 3.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EQB60683.1 - 0.00032 20.7 3.8 0.00032 20.7 3.8 3.0 3 1 0 3 3 3 1 Hr1 repeat PHD_2 PF13831.6 EQB60683.1 - 0.0071 15.9 3.1 0.0071 15.9 3.1 1.8 2 0 0 2 2 2 1 PHD-finger zf-RING_9 PF13901.6 EQB60683.1 - 0.0093 16.0 7.1 0.0093 16.0 7.1 2.7 1 1 0 2 2 2 1 Putative zinc-RING and/or ribbon DUF4791 PF16039.5 EQB60683.1 - 0.012 15.1 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) Zn_Tnp_IS1595 PF12760.7 EQB60683.1 - 0.015 15.3 0.3 0.039 13.9 0.3 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_2 PF03107.16 EQB60683.1 - 0.025 14.9 3.6 0.072 13.4 3.6 1.8 1 0 0 1 1 1 0 C1 domain OrfB_Zn_ribbon PF07282.11 EQB60683.1 - 0.08 12.9 0.9 0.22 11.5 0.9 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF5061 PF16587.5 EQB60683.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 17 kDa common-antigen outer membrane protein PHD PF00628.29 EQB60683.1 - 0.15 11.9 6.1 0.33 10.9 6.1 1.6 1 0 0 1 1 1 0 PHD-finger Tiam_CC_Ex PF18385.1 EQB60683.1 - 0.16 12.3 3.4 0.39 11.1 3.4 1.6 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Lzipper-MIP1 PF14389.6 EQB60683.1 - 0.26 11.6 7.7 0.2 12.0 0.7 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 zf-RING-like PF08746.11 EQB60683.1 - 0.27 11.6 4.2 0.67 10.3 4.2 1.7 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 EQB60683.1 - 0.35 10.8 4.4 0.7 9.9 4.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Mss51 PF13824.6 EQB60683.1 - 0.36 11.0 2.7 0.92 9.7 2.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 FYVE_2 PF02318.16 EQB60683.1 - 1.2 9.4 11.9 0.16 12.2 2.9 2.8 2 1 0 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.25 EQB60684.1 - 3.7e-49 167.5 0.7 3.7e-49 167.5 0.7 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60684.1 - 7.5e-24 84.4 0.1 1.4e-23 83.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB60684.1 - 1.1e-10 41.3 0.0 2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EQB60684.1 - 6.9e-05 21.8 0.4 0.00011 21.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EQB60684.1 - 0.00051 19.1 0.1 0.00051 19.1 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EQB60684.1 - 0.0028 17.6 0.2 0.023 14.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EQB60684.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIID-31kDa PF02291.15 EQB60685.1 - 2.3e-35 121.3 0.0 2.6e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 EQB60685.1 - 3e-08 33.9 0.0 4.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EQB60685.1 - 4.9e-07 29.7 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 EQB60685.1 - 3.8e-05 24.0 0.0 5.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EQB60685.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 EQB60685.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold SMC_N PF02463.19 EQB60687.1 - 4e-24 85.3 0.1 4.5e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EQB60687.1 - 5e-05 23.3 0.0 6.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system KNOX2 PF03791.13 EQB60687.1 - 0.093 12.3 0.1 0.28 10.7 0.1 1.8 1 0 0 1 1 1 0 KNOX2 domain Rot1 PF10681.9 EQB60689.1 - 0.073 12.6 0.3 0.18 11.3 0.3 1.6 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Spt20 PF12090.8 EQB60690.1 - 0.0063 16.2 10.9 0.0079 15.8 10.9 1.1 1 0 0 1 1 1 1 Spt20 family SRP-alpha_N PF04086.13 EQB60690.1 - 0.0072 16.3 16.2 0.008 16.1 16.2 1.0 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF4746 PF15928.5 EQB60690.1 - 0.29 10.5 16.0 0.29 10.5 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 EQB60690.1 - 0.89 8.3 13.9 0.96 8.1 13.9 1.0 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 EQB60690.1 - 0.93 9.8 24.3 1.1 9.5 24.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 EQB60690.1 - 1.1 9.4 8.7 1.2 9.2 8.7 1.1 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.13 EQB60690.1 - 2.5 6.8 18.0 2.8 6.6 18.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U79_P34 PF03064.16 EQB60690.1 - 3.2 7.1 18.7 3.9 6.8 18.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zip PF02535.22 EQB60690.1 - 3.4 6.8 10.0 3.6 6.7 10.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter PBP_sp32 PF07222.12 EQB60690.1 - 4 6.8 16.9 4.7 6.6 16.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.14 EQB60690.1 - 5 6.9 21.0 7.5 6.3 21.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EQB60690.1 - 7 4.8 20.6 7.4 4.7 20.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EQB60690.1 - 7 5.6 16.2 7.9 5.4 16.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NARP1 PF12569.8 EQB60690.1 - 7.2 5.4 23.1 8.2 5.2 23.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RVT_1 PF00078.27 EQB60692.1 - 1.6e-08 34.4 0.2 3.4e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EQB60693.1 - 4.4e-13 49.3 0.3 4.4e-13 49.3 0.3 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) REC104 PF17378.2 EQB60693.1 - 0.11 12.3 0.7 0.21 11.4 0.7 1.5 1 0 0 1 1 1 0 Meiotic recombination protein REC104 RRM_1 PF00076.22 EQB60695.1 - 5e-11 42.3 0.1 1.3e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_21 PF13304.6 EQB60697.1 - 0.025 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EQB60697.1 - 0.029 14.9 0.1 0.052 14.1 0.1 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 EQB60698.1 - 1.5e-05 25.5 0.0 0.00022 21.6 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Stn1_C PF12659.7 EQB60698.1 - 0.012 15.6 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH PRANC PF09372.10 EQB60698.1 - 0.15 12.4 9.9 0.075 13.4 3.2 2.2 1 1 1 2 2 2 0 PRANC domain TFIID_30kDa PF03540.13 EQB60699.1 - 1.6e-18 66.4 0.0 4.7e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Ins134_P3_kin_N PF17927.1 EQB60699.1 - 0.014 15.8 0.5 0.54 10.7 0.1 2.1 2 0 0 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Ribosomal_L18_c PF14204.6 EQB60699.1 - 0.092 13.7 0.3 0.1 13.5 0.3 1.2 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region PYRIN PF02758.16 EQB60699.1 - 0.13 12.4 0.6 0.47 10.6 0.4 1.9 1 1 1 2 2 2 0 PAAD/DAPIN/Pyrin domain PLDc_2 PF13091.6 EQB60700.1 - 2.2e-07 30.8 0.5 3e-07 30.4 0.5 1.2 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 EQB60700.1 - 0.0073 16.4 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif Rad51 PF08423.11 EQB60701.1 - 2.1e-123 410.6 0.0 2.6e-123 410.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EQB60701.1 - 2.3e-10 40.4 0.0 3e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EQB60701.1 - 4.6e-09 36.0 0.0 8.2e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.6 EQB60701.1 - 3.5e-08 33.9 0.5 8.9e-08 32.6 0.5 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 EQB60701.1 - 1.5e-05 24.7 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EQB60701.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EQB60701.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Ribosomal_S8e PF01201.22 EQB60702.1 - 1e-41 142.3 2.7 3.2e-41 140.7 2.7 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Histone_HNS PF00816.21 EQB60702.1 - 0.64 10.9 0.1 0.64 10.9 0.1 2.3 2 1 0 2 2 2 0 H-NS histone family MCM PF00493.23 EQB60703.1 - 1.5e-77 259.7 0.0 2.7e-77 258.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EQB60703.1 - 3.7e-18 65.7 2.9 6e-18 65.1 1.7 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 EQB60703.1 - 3.1e-16 59.4 0.3 6.2e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 EQB60703.1 - 8.3e-07 29.1 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EQB60703.1 - 1.1e-05 24.9 0.1 0.0063 15.9 0.0 2.7 1 1 2 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EQB60703.1 - 0.0018 18.0 0.2 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EQB60703.1 - 0.0022 17.8 0.0 0.0093 15.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EQB60703.1 - 0.0044 16.5 0.1 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EQB60703.1 - 0.64 10.4 4.1 0.73 10.3 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sec23_trunk PF04811.15 EQB60704.1 - 3.9e-38 131.4 0.0 8.1e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EQB60704.1 - 2.7e-13 50.5 0.1 6.7e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EQB60704.1 - 2.9e-13 49.5 0.1 5.8e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EQB60704.1 - 7.9e-10 38.6 8.1 2.5e-09 37.0 8.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EQB60704.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EQB60704.1 - 0.0021 17.4 0.3 0.0057 16.0 0.3 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain FYVE_2 PF02318.16 EQB60704.1 - 0.2 11.9 2.9 0.66 10.2 2.9 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger Proteasome PF00227.26 EQB60705.1 - 2.2e-24 86.0 0.1 2.6e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Bac_transf PF02397.16 EQB60705.1 - 0.059 13.0 0.1 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial sugar transferase DNA_pol_B_exo1 PF03104.19 EQB60706.1 - 8.4e-44 150.1 0.9 1e-43 149.8 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EQB60706.1 - 6.6e-29 100.9 0.0 8.4e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 EQB60706.1 - 6e-05 22.1 2.3 6.2e-05 22.0 0.5 1.9 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EQB60706.1 - 0.0017 18.4 0.1 0.01 15.8 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 EQB60706.1 - 0.0042 16.8 0.0 0.043 13.5 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease DNA_pol_B_exo2 PF10108.9 EQB60706.1 - 0.079 12.6 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_3 PF08408.10 EQB60706.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase family B viral insert DNA_pol_B_exo1 PF03104.19 EQB60707.1 - 5e-43 147.5 0.6 6.2e-43 147.2 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EQB60707.1 - 6.5e-29 100.9 0.0 8.2e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 EQB60707.1 - 5.8e-05 22.1 2.3 6.1e-05 22.1 0.5 1.9 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EQB60707.1 - 0.0016 18.4 0.1 0.01 15.9 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 EQB60707.1 - 0.0041 16.9 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease DNA_pol_B_exo2 PF10108.9 EQB60707.1 - 0.077 12.7 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_3 PF08408.10 EQB60707.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase family B viral insert DNA_pol_B PF00136.21 EQB60708.1 - 1.9e-76 257.7 4.9 2.6e-76 257.2 4.9 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EQB60708.1 - 1.9e-15 57.1 10.1 3.8e-15 56.1 10.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta INT_SG_DDX_CT_C PF15300.6 EQB60708.1 - 0.023 14.5 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DnaJ_CXXCXGXG PF00684.19 EQB60708.1 - 1.5 9.2 7.9 1.7 9.1 0.7 2.5 2 0 0 2 2 2 0 DnaJ central domain CENP-T_C PF15511.6 EQB60709.1 - 3.5e-06 27.1 0.0 4.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EQB60709.1 - 6.2e-05 23.4 0.2 0.00012 22.5 0.2 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EQB60709.1 - 0.0002 21.3 0.0 0.00027 20.9 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EQB60709.1 - 0.00027 21.3 0.0 0.00084 19.7 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein TFIID-31kDa PF02291.15 EQB60709.1 - 0.0069 16.5 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 EQB60709.1 - 0.0088 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) E3_binding PF02817.17 EQB60709.1 - 0.075 13.4 0.3 0.2 12.1 0.1 1.9 2 0 0 2 2 2 0 e3 binding domain CBFD_NFYB_HMF PF00808.23 EQB60709.1 - 0.083 13.2 0.2 0.2 12.0 0.0 1.8 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 EQB60709.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Histone PF00125.24 EQB60710.1 - 1e-41 142.4 3.5 1.1e-41 142.2 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EQB60710.1 - 2e-05 24.8 1.2 5.9e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 EQB60710.1 - 0.00021 21.9 2.2 0.00028 21.5 2.2 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EQB60710.1 - 0.0024 18.2 0.0 0.0052 17.1 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EQB60710.1 - 0.0063 16.6 0.9 0.0087 16.2 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EQB60710.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Cpn60_TCP1 PF00118.24 EQB60711.1 - 2.7e-73 247.3 2.0 3e-73 247.1 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRR_5 PF13306.6 EQB60711.1 - 0.005 16.8 0.3 0.005 16.8 0.3 2.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Cpn60_TCP1 PF00118.24 EQB60712.1 - 5.9e-38 130.7 1.5 6.7e-38 130.6 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nic96 PF04097.14 EQB60713.1 - 2.7e-09 36.0 0.1 3e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Nup93/Nic96 TerB_N PF13208.6 EQB60715.1 - 0.087 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 TerB N-terminal domain BsuBI_PstI_RE PF06616.11 EQB60716.1 - 0.0088 15.3 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain Toxin_28 PF08115.11 EQB60716.1 - 0.43 10.5 0.1 0.43 10.5 0.1 1.8 2 0 0 2 2 2 0 SFI toxin family RVT_1 PF00078.27 EQB60717.1 - 1.2e-11 44.5 0.3 4.3e-11 42.8 0.1 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_1_7 PF13843.6 EQB60718.1 - 2.3e-49 168.6 0.0 2.8e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Yae1_N PF09811.9 EQB60720.1 - 0.00024 20.7 5.6 0.12 12.1 1.1 2.6 1 1 1 2 2 2 2 Essential protein Yae1, N terminal MspA PF09203.11 EQB60720.1 - 0.026 14.4 4.9 0.035 14.0 4.9 1.4 1 0 0 1 1 1 0 MspA Keratin_2_head PF16208.5 EQB60720.1 - 0.081 13.1 19.4 1.1 9.4 5.7 2.0 1 1 1 2 2 2 0 Keratin type II head KRTAP PF11759.8 EQB60720.1 - 1.4 9.5 14.7 3.1e+02 2.0 14.7 2.4 1 1 0 1 1 1 0 Keratin-associated matrix FtsX PF02687.21 EQB60722.1 - 0.018 15.5 0.5 0.024 15.1 0.5 1.2 1 0 0 1 1 1 0 FtsX-like permease family DDE_1 PF03184.19 EQB60722.1 - 0.028 14.1 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease LRR_8 PF13855.6 EQB60723.1 - 2.1e-20 72.2 45.6 1.6e-05 24.5 3.2 7.2 2 1 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EQB60723.1 - 3.2e-20 71.9 50.3 2.2e-05 24.7 0.7 7.6 4 1 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB60723.1 - 0.0047 17.3 34.4 0.5 11.1 0.6 9.9 8 2 0 8 8 8 2 Leucine Rich Repeat Hexokinase_2 PF03727.16 EQB60724.1 - 4.6e-06 26.2 2.8 0.0055 16.2 0.0 3.0 1 1 1 2 2 2 2 Hexokinase Hexokinase_1 PF00349.21 EQB60724.1 - 0.044 13.7 0.1 0.2 11.6 0.0 2.1 2 1 0 2 2 2 0 Hexokinase Methyltransf_32 PF13679.6 EQB60724.1 - 0.17 11.9 0.5 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain RNA_pol_Rpb1_1 PF04997.12 EQB60725.1 - 2.7e-69 233.9 5.2 3.8e-69 233.4 5.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EQB60725.1 - 5.5e-68 228.4 0.1 1.1e-67 227.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EQB60725.1 - 1.9e-32 112.4 1.9 4e-32 111.3 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 Arc_PepC PF06819.11 EQB60725.1 - 0.0071 16.5 0.8 0.32 11.1 0.0 3.3 3 0 0 3 3 3 1 Archaeal Peptidase A24 C-terminal Domain RNA_pol_Rpb1_5 PF04998.17 EQB60726.1 - 1.9e-84 283.3 0.7 3.3e-83 279.2 0.7 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 EQB60726.1 - 7.7e-19 67.6 0.2 7.7e-19 67.6 0.2 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 TPR_8 PF13181.6 EQB60727.1 - 0.0062 16.6 0.0 0.038 14.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EQB60727.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PPV_E1_N PF00524.18 EQB60728.1 - 8e-06 26.3 6.1 8e-06 26.3 6.1 3.7 2 1 3 5 5 5 1 E1 Protein, N terminal domain RNA_pol_Rpb8 PF03870.15 EQB60729.1 - 9.1e-16 58.3 1.1 5.9e-13 49.2 1.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EQB60729.1 - 0.0013 18.8 0.7 0.0014 18.7 0.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase, subunit G DUF2147 PF09917.9 EQB60729.1 - 0.074 13.7 0.2 0.081 13.6 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) DBINO PF13892.6 EQB60730.1 - 9.3e-23 81.1 11.3 1.9e-22 80.0 11.3 1.5 1 0 0 1 1 1 1 DNA-binding domain SNF2_N PF00176.23 EQB60730.1 - 4.8e-21 74.9 0.1 8.5e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EQB60730.1 - 3.9e-05 23.7 0.0 3.9e-05 23.7 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EQB60732.1 - 8.4e-20 71.2 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EQB60732.1 - 1.9e-07 30.6 0.2 8.8e-07 28.4 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 LRR_8 PF13855.6 EQB60734.1 - 1.2e-35 121.1 60.2 3.9e-09 36.1 8.0 6.5 3 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EQB60734.1 - 1.6e-25 88.8 79.4 2.1e-07 31.2 4.4 8.6 3 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB60734.1 - 8.4e-08 31.9 31.2 0.002 17.6 5.4 4.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EQB60734.1 - 0.00052 20.2 64.7 2.6 8.9 0.1 12.2 10 3 0 10 10 10 4 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EQB60734.1 - 0.0019 18.2 0.8 7.7 6.7 0.0 4.6 3 1 1 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain RolB_RolC PF02027.17 EQB60734.1 - 0.13 11.9 0.1 5.4 6.6 0.0 2.2 1 1 0 2 2 2 0 RolB/RolC glucosidase family LRR_6 PF13516.6 EQB60734.1 - 1.2 9.4 43.3 0.96 9.7 0.1 8.9 9 0 0 9 9 9 0 Leucine Rich repeat RVT_1 PF00078.27 EQB60735.1 - 7.7e-10 38.7 0.0 9.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GlcNAc-1_reg PF18440.1 EQB60736.1 - 0.035 14.3 1.6 0.055 13.7 1.6 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF5323 PF17257.2 EQB60737.1 - 0.15 11.9 0.9 0.21 11.5 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5323) SAS-6_N PF16531.5 EQB60738.1 - 0.0013 19.3 1.0 0.0017 18.9 1.0 1.4 1 1 0 1 1 1 1 Centriolar protein SAS N-terminal DUF2288 PF10052.9 EQB60738.1 - 0.027 14.5 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Ribonuc_red_lgC PF02867.15 EQB60739.1 - 3.3e-22 78.7 0.3 3.7e-22 78.6 0.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain TFIID_20kDa PF03847.13 EQB60740.1 - 0.00011 22.6 0.2 0.00028 21.3 0.2 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EQB60740.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Myb_DNA-bind_4 PF13837.6 EQB60740.1 - 0.098 13.0 3.7 7.3 7.0 0.8 3.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain HJURP_C PF12347.8 EQB60740.1 - 1.6 8.8 4.5 1.9 8.5 1.6 2.5 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Ank_3 PF13606.6 EQB60741.1 - 0.00046 20.4 0.0 0.0034 17.7 0.0 2.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EQB60741.1 - 0.003 18.1 0.2 0.0094 16.5 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EQB60741.1 - 0.025 15.1 0.1 0.1 13.2 0.1 2.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) DUF3270 PF11674.8 EQB60741.1 - 0.29 11.3 7.8 0.087 13.0 4.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) UPF0113 PF03657.13 EQB60742.1 - 1e-21 76.9 0.3 1.9e-21 76.1 0.3 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 EQB60742.1 - 6e-20 71.6 1.0 1.3e-19 70.5 1.0 1.6 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 EQB60742.1 - 0.021 14.8 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 PUA domain Ribosomal_L27A PF00828.19 EQB60743.1 - 2.8e-11 44.2 0.0 3.1e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_POL_M_15KD PF02150.16 EQB60744.1 - 5.1e-08 32.7 1.7 5.1e-08 32.7 1.7 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EQB60744.1 - 3.6e-05 23.5 10.9 0.00094 19.0 2.8 3.3 2 2 0 2 2 2 2 Transcription factor S-II (TFIIS) DZR PF12773.7 EQB60744.1 - 0.014 15.4 4.2 0.2 11.7 0.8 2.4 2 1 0 2 2 2 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 EQB60744.1 - 0.05 13.3 14.0 0.13 12.0 0.5 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain zf-UBP PF02148.19 EQB60744.1 - 0.26 11.6 5.6 1.9 8.9 0.6 2.2 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Rpr2 PF04032.16 EQB60744.1 - 0.48 10.7 11.0 7.6 6.9 2.2 3.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.14 EQB60744.1 - 0.81 10.1 5.0 6.4 7.2 0.2 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme PHD PF00628.29 EQB60744.1 - 2.5 8.1 11.4 8.6 6.3 2.4 3.0 2 2 0 2 2 2 0 PHD-finger zf-CHY PF05495.12 EQB60744.1 - 2.9 8.4 12.5 0.43 11.1 1.5 2.6 1 1 0 2 2 2 0 CHY zinc finger zf-3CxxC_2 PF17180.4 EQB60744.1 - 3.6 8.4 10.6 9.1 7.1 0.1 3.5 3 1 0 3 3 3 0 Zinc-binding domain zinc_ribbon_10 PF10058.9 EQB60744.1 - 4.5 7.1 14.5 2.6 7.9 0.3 3.4 2 2 1 3 3 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Aida_N PF08910.10 EQB60745.1 - 0.0065 16.9 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 Aida N-terminus FYRN PF05964.14 EQB60745.1 - 0.025 14.4 1.3 0.048 13.5 1.3 1.4 1 0 0 1 1 1 0 F/Y-rich N-terminus Glyco_hydro_62 PF03664.13 EQB60745.1 - 0.21 10.9 1.3 0.37 10.0 0.1 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 62 Lactamase_B_6 PF16661.5 EQB60746.1 - 1.1e-20 74.0 0.1 2e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EQB60746.1 - 4.5e-17 62.7 0.0 6.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EQB60746.1 - 4e-10 39.5 0.0 5.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta-Casp PF10996.8 EQB60746.1 - 4.4e-10 39.8 0.2 7.7e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 EQB60746.1 - 9.9e-08 31.5 0.0 2.2e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 EQB60746.1 - 0.0015 18.4 0.0 0.0095 15.8 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EQB60747.1 - 2.2e-15 56.3 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF73-100_C PF11718.8 EQB60747.1 - 9.9e-12 44.9 0.4 1.6e-11 44.2 0.4 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EQB60747.1 - 1.1e-10 41.7 0.0 2.8e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain DUF1492 PF07374.11 EQB60749.1 - 0.11 12.6 9.3 0.1 12.7 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) zf-GRF PF06839.12 EQB60753.1 - 8.8e-08 32.1 9.1 8.8e-08 32.1 9.1 2.0 2 0 0 2 2 2 1 GRF zinc finger Topoisom_bac PF01131.20 EQB60754.1 - 1.5e-76 258.1 9.7 2.4e-42 145.4 1.3 4.0 3 1 2 5 5 5 3 DNA topoisomerase FERM_N PF09379.10 EQB60755.1 - 0.035 14.0 0.0 6.1 6.9 0.2 2.5 2 1 0 2 2 2 0 FERM N-terminal domain PTAC PF06130.12 EQB60755.1 - 0.038 14.2 0.3 0.81 9.9 0.1 2.3 2 0 0 2 2 2 0 Phosphate propanoyltransferase SpoU_sub_bind PF08032.12 EQB60755.1 - 0.17 12.2 0.7 9.7 6.5 0.0 2.7 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF3269 PF11673.8 EQB60757.1 - 0.042 14.2 1.5 0.042 14.2 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3269) SPT6_acidic PF14632.6 EQB60757.1 - 2.1 9.0 24.6 0.5 11.0 13.4 2.9 1 1 1 2 2 2 0 Acidic N-terminal SPT6 DUF1827 PF08860.10 EQB60757.1 - 3.2 8.1 8.5 1 9.7 5.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1827) RVP_2 PF08284.11 EQB60763.1 - 0.017 14.9 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1075 PF06388.11 EQB60763.1 - 5.2 7.1 7.1 16 5.6 6.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1075) RNaseH_like PF04308.12 EQB60763.1 - 5.7 6.9 7.5 0.32 10.9 0.8 2.2 3 0 0 3 3 3 0 Ribonuclease H-like Ricin_B_lectin PF00652.22 EQB60764.1 - 0.021 15.1 0.6 0.033 14.5 0.6 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain GHMP_kinases_N PF00288.26 EQB60766.1 - 3.8e-06 27.0 0.0 7.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EQB60766.1 - 0.029 14.7 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal AMP-binding PF00501.28 EQB60767.1 - 4.2e-48 164.0 0.0 5.7e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EQB60767.1 - 1.8e-13 51.2 0.0 3.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EQB60767.1 - 1.2e-07 31.5 0.8 3.4e-07 30.1 0.8 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Toprim PF01751.22 EQB60767.1 - 0.28 11.4 1.3 33 4.8 0.0 3.4 3 1 0 3 3 3 0 Toprim domain Pkinase PF00069.25 EQB60770.1 - 4.2e-43 147.6 1.0 6.3e-43 147.0 1.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60770.1 - 1.7e-24 86.6 0.0 2.2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB60770.1 - 1.2e-11 44.5 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 EQB60770.1 - 0.018 14.7 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.14 EQB60770.1 - 0.02 14.2 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EQB60770.1 - 0.051 13.5 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EQB60770.1 - 0.067 12.8 2.1 0.078 12.6 0.5 1.8 1 1 0 2 2 2 0 RIO1 family Pkinase PF00069.25 EQB60771.1 - 1.1e-32 113.4 0.0 1.7e-32 112.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60771.1 - 1.1e-16 60.9 0.0 1.3e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB60771.1 - 9.3e-12 44.8 0.0 1.2e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 EQB60771.1 - 0.016 14.8 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.14 EQB60771.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EQB60771.1 - 0.032 14.1 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EQB60771.1 - 0.07 12.7 0.4 0.07 12.7 0.4 1.5 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 EQB60771.1 - 0.12 11.3 0.3 0.16 10.9 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EQB60771.1 - 0.17 10.6 0.3 0.21 10.3 0.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase UDPGP PF01704.18 EQB60772.1 - 2.7e-118 395.2 0.2 3.4e-118 394.9 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Dus PF01207.17 EQB60773.1 - 3.5e-46 157.7 0.9 5.6e-27 94.6 0.1 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EQB60773.1 - 0.00023 20.7 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein PEP_mutase PF13714.6 EQB60773.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NMO PF03060.15 EQB60773.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 EQB60773.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Nif11 PF07862.11 EQB60773.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Nif11 domain CPSase_L_D3 PF02787.19 EQB60774.1 - 0.043 14.1 0.2 0.044 14.1 0.2 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain KIX_2 PF16987.5 EQB60775.1 - 0.0004 20.3 4.7 0.001 19.0 4.7 1.7 1 0 0 1 1 1 1 KIX domain Serpin PF00079.20 EQB60776.1 - 3.8e-39 135.1 3.1 4.2e-39 134.9 3.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF2922 PF11148.8 EQB60776.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) DUF4842 PF16130.5 EQB60776.1 - 0.29 11.3 2.2 0.33 11.1 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4842) CLTH PF10607.9 EQB60778.1 - 3.2e-08 33.6 9.1 4.1e-08 33.2 8.0 1.7 1 1 1 2 2 2 2 CTLH/CRA C-terminal to LisH motif domain TruD PF01142.18 EQB60779.1 - 6.1e-36 124.1 3.6 3.7e-27 95.2 3.8 4.2 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) CH PF00307.31 EQB60780.1 - 2.2e-10 40.7 0.2 4.8e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain RasGAP_C PF03836.15 EQB60782.1 - 3.7e-13 49.8 8.4 6.9e-13 48.9 8.4 1.4 1 0 0 1 1 1 1 RasGAP C-terminus ubiquitin PF00240.23 EQB60783.1 - 3.2e-09 36.4 2.6 5.6e-09 35.6 2.6 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 EQB60783.1 - 0.001 19.0 0.3 0.0025 17.7 0.3 1.7 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 EQB60783.1 - 0.0011 18.7 2.3 0.0011 18.7 2.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EQB60783.1 - 0.0049 17.3 1.7 0.0069 16.8 1.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain APG12 PF04110.13 EQB60783.1 - 0.013 15.9 3.5 0.027 14.8 0.3 2.6 2 2 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Ubiquitin_4 PF18036.1 EQB60783.1 - 0.058 13.4 3.4 0.22 11.6 0.3 2.7 2 1 1 3 3 3 0 Ubiquitin-like domain Tudor_RapA PF18337.1 EQB60783.1 - 0.16 12.1 0.2 0.36 11.0 0.2 1.5 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain DUF4042 PF13251.6 EQB60784.1 - 0.057 13.1 0.3 0.092 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) Methyltransf_19 PF04672.12 EQB60784.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase ASF1_hist_chap PF04729.13 EQB60786.1 - 1.5e-27 96.4 0.9 2.2e-27 95.9 0.9 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone CDC45 PF02724.14 EQB60786.1 - 0.0018 16.7 6.0 0.0019 16.6 6.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EQB60786.1 - 3.4 5.7 18.3 4.8 5.3 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.19 EQB60787.1 - 2.6e-08 34.3 0.3 3.3e-08 34.0 0.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2880 PF11082.8 EQB60787.1 - 0.059 13.7 0.0 0.17 12.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) PNK3P PF08645.11 EQB60788.1 - 4.4e-35 120.8 2.8 4.4e-35 120.8 2.8 1.5 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.6 EQB60788.1 - 2.6e-09 37.4 5.3 2.2e-08 34.4 5.3 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EQB60788.1 - 0.0003 20.9 0.0 0.00093 19.3 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EQB60788.1 - 0.007 16.7 0.0 0.19 12.0 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EQB60788.1 - 0.017 14.8 3.7 0.022 14.5 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 EQB60788.1 - 0.033 14.0 2.1 0.037 13.8 0.5 1.9 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Annexin_like PF18411.1 EQB60788.1 - 0.057 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Annexin-like domain Hydrolase_like PF13242.6 EQB60788.1 - 0.063 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4522 PF15022.6 EQB60789.1 - 0.13 12.6 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4522) His_Phos_2 PF00328.22 EQB60790.1 - 4.4e-13 49.3 0.2 3.6e-09 36.5 0.1 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-HC5HC2H PF13771.6 EQB60790.1 - 0.0094 16.2 0.7 0.0094 16.2 0.7 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EQB60790.1 - 0.034 14.3 1.7 0.079 13.1 0.6 2.1 2 0 0 2 2 2 0 PHD-zinc-finger like domain Fas_alpha_ACP PF18325.1 EQB60790.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain Fas_alpha_ACP PF18325.1 EQB60791.1 - 0.023 15.0 0.1 0.049 14.0 0.0 1.5 2 0 0 2 2 2 0 Fatty acid synthase subunit alpha Acyl carrier domain His_Phos_2 PF00328.22 EQB60791.1 - 0.051 12.9 0.2 0.088 12.1 0.2 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AAA PF00004.29 EQB60792.1 - 1.8e-45 154.6 0.0 3.4e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EQB60792.1 - 4.4e-09 36.7 0.0 9.2e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EQB60792.1 - 4.4e-08 32.8 0.1 8.3e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EQB60792.1 - 3.3e-07 30.8 0.1 0.00012 22.5 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EQB60792.1 - 4.3e-07 30.0 0.1 1.8e-06 28.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB60792.1 - 6.7e-06 26.4 0.8 0.019 15.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 EQB60792.1 - 7e-06 25.9 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EQB60792.1 - 0.00064 20.3 0.0 0.0016 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EQB60792.1 - 0.0029 16.9 0.0 0.0051 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EQB60792.1 - 0.003 17.1 0.0 0.0067 16.0 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 EQB60792.1 - 0.0035 16.6 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 EQB60792.1 - 0.0042 17.0 0.0 0.007 16.2 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EQB60792.1 - 0.0044 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EQB60792.1 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EQB60792.1 - 0.0065 16.2 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EQB60792.1 - 0.0087 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EQB60792.1 - 0.016 14.7 0.1 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EQB60792.1 - 0.02 14.6 0.0 0.073 12.8 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EQB60792.1 - 0.02 15.1 0.0 0.037 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EQB60792.1 - 0.022 14.1 0.1 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EQB60792.1 - 0.025 14.5 0.0 0.31 10.9 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EQB60792.1 - 0.026 13.8 0.1 0.078 12.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EQB60792.1 - 0.029 14.8 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EQB60792.1 - 0.032 13.8 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EQB60792.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EQB60792.1 - 0.037 13.1 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 EQB60792.1 - 0.051 13.6 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EQB60792.1 - 0.07 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EQB60792.1 - 0.13 12.0 0.1 0.41 10.4 0.0 1.7 1 1 0 2 2 2 0 AAA domain DUF5088 PF17008.5 EQB60793.1 - 2.5e-29 102.3 13.8 2.5e-29 102.3 13.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5088) S1_2 PF13509.6 EQB60793.1 - 0.029 14.4 0.3 4.3 7.5 0.3 3.2 2 0 0 2 2 2 0 S1 domain DUF4024 PF13216.6 EQB60793.1 - 0.03 14.2 0.4 0.081 12.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) Gti1_Pac2 PF09729.9 EQB60794.1 - 7.5e-37 127.2 4.1 3.4e-31 108.7 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family DUF2439 PF10382.9 EQB60794.1 - 0.0032 17.8 0.8 0.0064 16.8 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Tim17 PF02466.19 EQB60795.1 - 1.9e-07 31.4 0.1 3.6e-06 27.3 0.1 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0113_N PF17833.1 EQB60795.1 - 0.061 13.9 0.1 15 6.2 0.0 2.1 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain DUF2407_C PF13373.6 EQB60795.1 - 0.17 12.1 0.4 4.2 7.5 0.1 2.1 1 1 1 2 2 2 0 DUF2407 C-terminal domain Nup35_RRM PF05172.13 EQB60796.1 - 0.0089 16.0 0.3 0.15 12.0 0.3 2.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF956 PF06115.11 EQB60796.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF956) DUF455 PF04305.14 EQB60796.1 - 0.17 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Cyclin_N PF00134.23 EQB60797.1 - 4.9e-05 23.1 0.4 5.6e-05 22.9 0.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain UBA PF00627.31 EQB60798.1 - 0.00014 21.7 0.8 0.0099 15.8 0.0 3.0 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 EQB60798.1 - 0.00058 19.6 0.6 0.0011 18.6 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family HOIP-UBA PF16678.5 EQB60798.1 - 0.0054 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 HOIP UBA domain pair PQQ_3 PF13570.6 EQB60799.1 - 6.7e-05 23.2 0.0 0.47 11.0 0.0 4.4 5 0 0 5 5 5 2 PQQ-like domain Fe_hyd_lg_C PF02906.14 EQB60800.1 - 4.5e-23 82.2 0.0 6.3e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF4760 PF15956.5 EQB60800.1 - 0.021 15.0 0.4 0.049 13.8 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) zf-RING_2 PF13639.6 EQB60801.1 - 3.4e-12 46.5 7.9 5.4e-12 45.9 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EQB60801.1 - 2.9e-10 39.7 2.1 6.7e-10 38.5 2.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EQB60801.1 - 1.1e-08 34.7 8.0 1.9e-08 34.0 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EQB60801.1 - 1.8e-07 30.9 8.5 3.3e-07 30.0 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB60801.1 - 1.3e-06 28.2 6.4 2.1e-06 27.6 6.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EQB60801.1 - 6e-06 26.2 1.5 6e-06 26.2 1.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EQB60801.1 - 6.2e-06 26.4 11.0 4.5e-05 23.6 11.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EQB60801.1 - 1.4e-05 24.8 5.5 2.5e-05 24.0 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EQB60801.1 - 3.5e-05 23.6 5.7 5.4e-05 23.0 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EQB60801.1 - 0.00095 19.2 2.3 0.00095 19.2 2.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EQB60801.1 - 0.0061 16.2 5.3 0.011 15.4 5.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 EQB60801.1 - 0.0098 16.0 2.8 0.019 15.0 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 EQB60801.1 - 0.089 13.0 3.7 0.23 11.7 3.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EQB60801.1 - 0.18 11.7 4.8 0.33 10.8 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EQB60801.1 - 0.23 11.6 7.7 0.46 10.7 7.7 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EQB60801.1 - 0.29 11.2 4.8 0.67 10.0 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 EQB60801.1 - 0.76 10.0 7.4 3.9 7.7 7.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EQB60801.1 - 1.3 9.4 6.5 2.6 8.4 6.5 1.5 1 0 0 1 1 1 0 RING-like domain Peptidase_C50 PF03568.17 EQB60802.1 - 5.9e-07 28.9 1.4 1.1e-06 28.1 1.4 1.5 1 1 0 1 1 1 1 Peptidase family C50 Nbl1_Borealin_N PF10444.9 EQB60802.1 - 0.81 9.4 4.1 0.57 9.9 1.8 1.9 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal Cullin_Nedd8 PF10557.9 EQB60803.1 - 0.17 12.0 4.8 0.1 12.7 1.3 2.4 2 0 0 2 2 2 0 Cullin protein neddylation domain LRR_4 PF12799.7 EQB60805.1 - 2e-13 50.3 26.1 3.4e-06 27.3 4.2 8.0 3 3 6 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60805.1 - 1e-10 41.2 19.2 1.7e-05 24.5 1.0 7.4 5 2 2 8 8 8 5 Leucine rich repeat BfiI_DBD PF18243.1 EQB60805.1 - 0.092 12.3 2.6 0.33 10.6 2.6 1.9 1 1 0 1 1 1 0 Metal-independent restriction enzyme BfiI DNA binding domain LRR_6 PF13516.6 EQB60805.1 - 0.38 10.9 44.8 2.6 8.3 0.0 10.5 11 1 1 12 12 12 0 Leucine Rich repeat LRR_1 PF00560.33 EQB60805.1 - 7.2 7.6 41.3 18 6.4 0.5 9.4 10 1 0 10 10 10 0 Leucine Rich Repeat LRR_4 PF12799.7 EQB60808.1 - 7.9e-13 48.4 17.9 8.8e-06 26.0 1.6 4.2 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60808.1 - 6e-11 41.9 13.9 7.5e-06 25.6 1.1 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EQB60808.1 - 7.1e-08 31.9 12.9 0.4 10.8 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EQB60808.1 - 4e-06 26.6 16.3 2.5 9.0 0.6 6.3 5 1 0 5 5 5 4 Leucine Rich Repeat Yqai PF09466.10 EQB60808.1 - 0.056 13.8 0.1 0.056 13.8 0.1 3.6 1 1 2 3 3 3 0 Hypothetical protein Yqai DDR_swiveling PF18427.1 EQB60809.1 - 0.26 11.3 5.2 0.62 10.1 5.2 1.6 1 0 0 1 1 1 0 DD-reactivating factor swiveling domain FH2 PF02181.23 EQB60810.1 - 3.8e-11 42.7 15.7 4.6e-11 42.5 15.7 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain TAF PF02969.17 EQB60811.1 - 8e-20 70.8 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EQB60812.1 - 3.1e-16 59.5 0.0 5.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain RPM2 PF08579.11 EQB60812.1 - 0.067 13.6 4.2 1.2 9.5 1.1 2.4 1 1 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) TRM PF02005.16 EQB60813.1 - 1.2e-65 222.2 15.9 7.9e-64 216.2 15.9 2.0 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.6 EQB60813.1 - 7.6e-05 22.5 0.8 7.6e-05 22.5 0.8 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EQB60813.1 - 0.035 13.7 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RRM_1 PF00076.22 EQB60814.1 - 8.1e-60 198.6 13.3 3.7e-16 58.7 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EQB60814.1 - 7.8e-09 35.2 4.8 0.00019 21.0 0.2 3.4 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EQB60814.1 - 9.9e-09 35.1 2.2 0.14 12.2 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EQB60814.1 - 0.00012 22.1 2.8 1.9 8.7 0.0 4.6 4 2 0 4 4 4 2 RNA recognition motif Nup35_RRM PF05172.13 EQB60814.1 - 0.00038 20.4 8.2 0.015 15.2 0.3 3.9 3 2 1 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EQB60814.1 - 0.0072 16.2 0.4 6.2 6.7 0.0 3.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RL PF17797.1 EQB60814.1 - 0.036 14.0 6.1 0.8 9.7 0.1 4.1 5 0 0 5 5 5 0 RL domain DnaJ PF00226.31 EQB60815.1 - 5.4e-17 61.7 1.5 5.4e-17 61.7 1.5 2.3 2 0 0 2 2 2 1 DnaJ domain DUF349 PF03993.12 EQB60815.1 - 0.019 15.2 2.7 0.042 14.1 2.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) PHD PF00628.29 EQB60816.1 - 0.0002 21.2 11.9 0.00032 20.5 11.9 1.3 1 0 0 1 1 1 1 PHD-finger Rad60-SLD PF11976.8 EQB60817.1 - 2.2e-12 46.6 0.4 1.3e-11 44.2 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like PIG-L PF02585.17 EQB60817.1 - 7.3e-11 42.8 0.0 1.4e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ubiquitin PF00240.23 EQB60817.1 - 4.9e-07 29.4 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TMEM208_SND2 PF05620.11 EQB60817.1 - 4.1e-06 26.7 0.1 7.5e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Ubiquitin_5 PF18037.1 EQB60817.1 - 0.073 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain CENP-F_leu_zip PF10473.9 EQB60817.1 - 0.9 9.6 6.7 1.3 9.1 1.8 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPL4 PF05021.15 EQB60818.1 - 4.6e-39 134.6 3.5 9.4e-39 133.6 3.5 1.6 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EQB60818.1 - 2.8e-25 89.1 8.1 9.5e-25 87.4 8.1 1.9 1 1 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.18 EQB60818.1 - 0.00033 19.9 1.5 0.00033 19.9 1.5 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others TEX12 PF15219.6 EQB60818.1 - 0.003 17.9 0.7 2.5 8.5 0.0 3.0 2 0 0 2 2 2 2 Testis-expressed 12 UN_NPL4 PF11543.8 EQB60818.1 - 0.003 18.0 1.0 0.056 13.9 0.1 2.7 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 RecR PF02132.15 EQB60818.1 - 2.6 7.7 6.9 0.093 12.3 0.5 2.0 2 0 0 2 2 2 0 RecR protein DnaJ_C PF01556.18 EQB60819.1 - 5.1e-28 98.0 1.1 9.1e-28 97.2 1.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EQB60819.1 - 3.6e-13 49.4 2.3 4.7e-12 45.8 1.6 2.6 2 1 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EQB60819.1 - 1.3e-09 38.2 17.1 4.4e-09 36.6 17.1 2.0 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EQB60819.1 - 0.0038 17.2 9.9 0.2 11.6 0.9 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EQB60819.1 - 0.72 9.9 8.6 1.9 8.6 8.6 1.8 1 0 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 EQB60819.1 - 1 9.8 6.4 1.1 9.7 3.6 2.6 2 1 1 3 3 3 0 Restriction alleviation protein Lar Pkinase PF00069.25 EQB60820.1 - 4e-34 118.2 0.1 4.5e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60820.1 - 5.4e-16 58.7 0.0 6.1e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB60820.1 - 3.4e-05 23.3 0.0 3.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EQB60820.1 - 0.00042 19.2 0.0 0.00055 18.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PUF PF00806.19 EQB60821.1 - 0.00013 21.5 3.1 0.0013 18.3 0.7 3.6 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat Ndufs5 PF10200.9 EQB60821.1 - 0.0089 16.3 0.6 0.024 14.9 0.6 1.8 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa USP7_ICP0_bdg PF12436.8 EQB60822.1 - 0.0019 17.6 0.3 0.0025 17.2 0.3 1.2 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 EMP24_GP25L PF01105.24 EQB60822.1 - 0.004 17.1 2.4 0.0061 16.5 2.4 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Clc-like PF07062.12 EQB60822.1 - 0.059 12.8 0.4 0.14 11.6 0.4 1.6 1 1 0 1 1 1 0 Clc-like DEAD PF00270.29 EQB60823.1 - 4.6e-26 91.6 0.2 1.1e-25 90.5 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 EQB60823.1 - 5.3e-15 55.3 6.6 5.3e-15 55.3 6.6 2.3 2 0 0 2 2 2 1 Sec63 Brl domain ResIII PF04851.15 EQB60823.1 - 3.6e-14 53.1 0.5 3.6e-14 53.1 0.5 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EQB60823.1 - 2.9e-12 46.9 0.2 2.9e-12 46.9 0.2 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EQB60823.1 - 0.015 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EQB60823.1 - 0.018 15.3 0.0 0.29 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EQB60823.1 - 0.019 14.7 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 EQB60823.1 - 0.035 13.9 0.2 0.67 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 EQB60823.1 - 0.063 12.3 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 EQB60823.1 - 0.09 12.2 0.1 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Gp_dh_C PF02800.20 EQB60824.1 - 2.4e-30 105.2 0.1 5.7e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EQB60824.1 - 1.5e-27 95.9 0.1 1.1e-26 93.1 0.0 2.3 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sec3_C PF09763.9 EQB60824.1 - 2.8e-09 35.9 11.6 2.8e-09 35.9 11.6 1.9 1 1 1 2 2 2 1 Exocyst complex component Sec3 2-Hacid_dh_C PF02826.19 EQB60824.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CwfJ_C_2 PF04676.14 EQB60824.1 - 0.058 14.3 0.4 0.18 12.7 0.4 2.0 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.25 EQB60825.1 - 1.7e-46 158.7 0.9 2.1e-46 158.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60825.1 - 1.9e-29 102.8 0.0 3.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EQB60825.1 - 2.5e-06 26.7 11.1 8.4e-05 21.7 10.0 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EQB60825.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like UB2H PF14814.6 EQB60825.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain Tudor_2 PF18104.1 EQB60825.1 - 0.66 9.7 6.2 5 6.9 0.4 3.2 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Pkinase PF00069.25 EQB60826.1 - 2.6e-20 72.9 0.0 3.3e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60826.1 - 5.7e-10 38.9 0.0 7.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PND PF17949.1 EQB60827.1 - 0.072 13.3 0.4 0.64 10.3 0.2 1.9 1 1 1 2 2 2 0 FANCM pseudonuclease domain DUF2873 PF11395.8 EQB60828.1 - 0.0062 16.4 2.2 0.011 15.5 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2873) Scs3p PF10261.9 EQB60828.1 - 0.04 13.4 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM ABC2_membrane_3 PF12698.7 EQB60828.1 - 0.24 10.5 7.7 0.34 10.0 7.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Pectate_lyase_3 PF12708.7 EQB60828.1 - 0.44 10.4 7.8 0.51 10.2 7.8 1.1 1 0 0 1 1 1 0 Pectate lyase superfamily protein zf-RRPl_C4 PF17026.5 EQB60829.1 - 1e-22 80.3 25.2 1.7e-22 79.5 25.2 1.3 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 EQB60829.1 - 0.19 11.8 8.2 5.9 7.0 8.2 2.4 1 1 0 1 1 1 0 Double zinc ribbon Methyltr_RsmB-F PF01189.17 EQB60830.1 - 5.4e-64 215.5 0.0 8.2e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EQB60830.1 - 6.9e-14 52.1 0.0 3.5e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EQB60830.1 - 6.9e-06 26.3 0.0 1.2e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Phage_holin_2_4 PF16082.5 EQB60830.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Methyltransf_31 PF13847.6 EQB60830.1 - 0.12 12.1 0.2 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 Methyltransferase domain Presenilin PF01080.17 EQB60832.1 - 2.4 6.8 6.6 2.8 6.6 6.6 1.1 1 0 0 1 1 1 0 Presenilin AsnC_trans_reg PF01037.21 EQB60833.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Kinase-PPPase PF03618.14 EQB60834.1 - 0.026 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Kinase/pyrophosphorylase DUF2674 PF10879.8 EQB60834.1 - 0.17 11.5 3.8 0.31 10.6 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) Glutaredoxin PF00462.24 EQB60835.1 - 2.3e-08 34.1 0.1 3.8e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Pannexin_like PF12534.8 EQB60835.1 - 0.014 14.5 3.4 0.017 14.2 3.4 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 GST_N PF02798.20 EQB60835.1 - 0.046 14.1 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EQB60835.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EQB60836.1 - 0.0019 18.4 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EQB60836.1 - 0.075 13.5 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EQB60837.1 - 0.0019 18.4 0.0 0.0025 18.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EQB60837.1 - 0.075 13.5 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Acetyltransf_15 PF17013.5 EQB60838.1 - 2.3e-24 86.0 0.1 2.5e-24 85.9 0.1 1.0 1 0 0 1 1 1 1 Putative acetyl-transferase SapB_2 PF03489.17 EQB60838.1 - 0.1 12.8 0.1 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 2 TLC PF03219.14 EQB60841.1 - 2.2e-14 53.1 2.4 2.3e-14 53.0 2.4 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter LapA_dom PF06305.11 EQB60841.1 - 0.025 14.4 2.2 0.064 13.1 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Claudin_3 PF06653.11 EQB60841.1 - 0.12 12.3 5.9 0.18 11.7 5.8 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TLC PF03219.14 EQB60842.1 - 7.8e-23 80.9 11.6 8.8e-23 80.8 11.6 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Dynamin_M PF01031.20 EQB60843.1 - 2.3e-18 66.4 2.5 2.3e-18 66.4 2.5 3.3 1 1 1 2 2 2 1 Dynamin central region Musclin PF11037.8 EQB60844.1 - 0.035 14.0 0.2 0.07 13.1 0.2 1.4 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Furin-like_2 PF15913.5 EQB60845.1 - 0.047 13.9 1.9 0.068 13.3 1.9 1.3 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich Connexin43 PF03508.13 EQB60845.1 - 7.5 6.2 13.8 5.4 6.7 3.7 2.6 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) RT_RNaseH PF17917.1 EQB60846.1 - 0.012 15.9 0.1 0.037 14.3 0.1 1.9 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 EQB60846.1 - 0.013 15.2 0.1 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 EQB60846.1 - 0.027 14.5 0.0 0.12 12.4 0.0 2.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 EQB60846.1 - 0.071 13.7 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF5300 PF17224.3 EQB60846.1 - 0.16 12.2 5.2 0.1 12.9 0.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5300) Tubulin PF00091.25 EQB60848.1 - 3.7e-66 223.1 0.0 8.1e-66 222.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EQB60848.1 - 7.4e-49 165.1 0.1 1.2e-48 164.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EQB60848.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.25 EQB60849.1 - 8.5e-52 176.2 0.0 2.1e-51 174.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EQB60849.1 - 6.1e-49 165.4 0.1 9.9e-49 164.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EQB60849.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain TRA-1_regulated PF02343.16 EQB60852.1 - 0.015 15.4 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 TRA-1 regulated protein R03H10.4 BsuBI_PstI_RE PF06616.11 EQB60853.1 - 0.032 13.5 0.2 0.098 11.9 0.1 1.8 1 1 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain Poty_coat PF00767.18 EQB60854.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Potyvirus coat protein LRR_6 PF13516.6 EQB60855.1 - 0.0014 18.5 1.0 0.0014 18.5 1.0 4.3 4 1 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.7 EQB60855.1 - 0.028 14.8 32.8 4.2 7.9 2.4 6.1 4 2 1 6 6 6 0 Leucine Rich repeats (2 copies) BAR PF03114.18 EQB60855.1 - 0.072 12.7 1.0 0.11 12.2 1.0 1.3 1 0 0 1 1 1 0 BAR domain LRR_1 PF00560.33 EQB60855.1 - 2.3 9.1 28.7 0.37 11.5 0.5 7.0 7 1 0 7 7 7 0 Leucine Rich Repeat RNA_pol_Rbc25 PF08292.12 EQB60856.1 - 1.2e-14 54.7 6.9 1.5e-10 41.4 3.3 2.3 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 S1 PF00575.23 EQB60856.1 - 1.2e-05 25.5 2.5 3.4e-05 24.1 2.5 1.6 1 1 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 EQB60856.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.6 1 1 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Ribosomal_S20p PF01649.18 EQB60857.1 - 0.0094 16.6 0.8 0.018 15.7 0.0 1.8 3 0 0 3 3 3 1 Ribosomal protein S20 CX PF01705.19 EQB60857.1 - 0.061 13.9 3.3 5.6 7.6 0.0 2.3 2 0 0 2 2 2 0 CX module Tubulin PF00091.25 EQB60858.1 - 9e-66 221.8 0.4 1.7e-65 221.0 0.1 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EQB60858.1 - 1.5e-17 63.9 0.4 2.8e-17 63.1 0.4 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EQB60858.1 - 4e-06 27.1 0.0 7.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EQB60858.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EQB60858.1 - 0.04 13.1 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Myb_DNA-binding PF00249.31 EQB60866.1 - 9.3e-07 29.0 2.9 0.00054 20.1 0.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EQB60866.1 - 0.0081 16.4 0.8 0.0081 16.4 0.8 3.3 2 1 1 3 3 3 1 Myb-like DNA-binding domain zf-rbx1 PF12678.7 EQB60867.1 - 8.5e-22 77.2 11.5 1.1e-21 76.9 11.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EQB60867.1 - 1.6e-15 56.9 8.6 2e-15 56.6 8.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EQB60867.1 - 2.8e-08 34.0 6.6 2.8e-08 34.0 6.6 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB60867.1 - 8.9e-06 25.4 12.0 2.2e-05 24.2 7.9 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EQB60867.1 - 8.6e-05 22.2 6.3 0.0062 16.3 6.3 2.3 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EQB60867.1 - 9.7e-05 22.2 10.4 0.00036 20.3 10.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 EQB60867.1 - 0.011 15.8 9.2 0.025 14.7 9.2 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.6 EQB60867.1 - 0.021 14.7 10.0 0.092 12.6 3.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 EQB60867.1 - 0.18 12.0 8.5 0.35 11.1 1.1 2.4 1 1 1 2 2 2 0 Zinc-ribbon like family FANCL_C PF11793.8 EQB60867.1 - 0.23 11.6 9.5 0.59 10.3 9.5 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 EQB60867.1 - 0.28 11.2 7.6 1.4 9.0 7.6 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.6 EQB60867.1 - 0.3 11.4 11.0 4.6 7.6 11.0 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 EQB60867.1 - 0.35 11.2 11.1 1.5 9.2 11.1 1.9 1 1 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.6 EQB60867.1 - 0.48 10.4 13.0 16 5.6 13.0 2.6 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EQB60867.1 - 0.7 9.6 14.9 17 5.1 14.9 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type RT_RNaseH_2 PF17919.1 EQB60870.1 - 1.9e-17 63.1 0.0 6.4e-17 61.4 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 EQB60870.1 - 9.4e-09 35.7 0.0 2.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EQB60870.1 - 2.1e-07 31.5 0.0 5.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 EQB60870.1 - 2.7e-07 30.8 0.1 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 EQB60870.1 - 3.4e-05 23.6 0.0 0.0001 22.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 EQB60870.1 - 0.0018 18.1 0.3 0.033 14.0 0.0 2.8 3 0 0 3 3 3 1 Putative peptidase (DUF1758) RVP PF00077.20 EQB60870.1 - 0.024 15.0 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-C2H2_2 PF12756.7 EQB60870.1 - 4.6 7.6 17.6 0.2 12.0 0.5 4.3 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) YojJ PF10372.9 EQB60870.1 - 4.9 7.3 12.6 0.11 12.6 1.8 3.8 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus Ribosomal_L24e PF01246.20 EQB60872.1 - 3.7e-11 43.1 0.1 5.9e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L24e TLD PF07534.16 EQB60873.1 - 0.0021 18.3 12.3 0.38 11.0 1.7 3.0 1 1 1 2 2 2 2 TLD LRR_8 PF13855.6 EQB60874.1 - 3.1e-12 46.1 32.3 2.1e-05 24.2 12.2 4.3 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EQB60874.1 - 8.8e-12 45.1 42.9 0.00036 20.9 4.1 5.5 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60875.1 - 3.8e-17 61.8 24.5 4.1e-09 36.1 4.5 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EQB60875.1 - 4.4e-11 42.8 51.7 1.2e-05 25.5 12.4 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB60875.1 - 0.00061 20.0 25.4 0.38 11.5 0.5 5.2 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_5 PF13306.6 EQB60875.1 - 0.0015 18.5 4.1 0.62 10.0 0.1 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EQB60875.1 - 0.34 11.1 0.1 0.34 11.1 0.1 5.0 6 0 0 6 6 6 0 Leucine Rich repeat FNIP PF05725.12 EQB60875.1 - 0.57 10.4 23.4 0.36 11.0 1.4 4.5 1 1 3 4 4 4 0 FNIP Repeat LRR_2 PF07723.13 EQB60875.1 - 1.9 9.3 6.4 3.3 8.5 1.9 3.5 3 1 0 3 3 3 0 Leucine Rich Repeat Methyltransf_12 PF08242.12 EQB60877.1 - 0.027 15.2 0.2 0.075 13.8 0.2 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-RVT PF13966.6 EQB60878.1 - 0.0065 17.2 0.3 0.02 15.6 0.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DDE_Tnp_1_7 PF13843.6 EQB60879.1 - 1.4e-36 126.5 0.0 1.6e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 EQB60880.1 - 1.5e-07 31.1 0.1 1.5e-07 31.1 0.1 1.4 2 0 0 2 2 2 1 Transposase IS4 Tom5 PF10642.9 EQB60880.1 - 0.21 11.6 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase POT1PC PF16686.5 EQB60882.1 - 0.0012 18.8 4.4 0.34 10.8 0.5 4.0 3 1 0 3 3 3 1 ssDNA-binding domain of telomere protection protein TFIIS_C PF01096.18 EQB60882.1 - 0.2 11.6 1.6 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Proteasome PF00227.26 EQB60885.1 - 2.8e-13 49.8 0.0 3e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PUF PF00806.19 EQB60886.1 - 1.1e-20 72.1 1.9 5.9e-07 28.8 0.1 3.6 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat PUF PF00806.19 EQB60887.1 - 7e-15 53.8 1.2 2.1e-07 30.2 0.4 2.6 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat Aa_trans PF01490.18 EQB60888.1 - 1.5e-19 70.1 37.9 5.2e-10 38.6 4.0 2.8 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein WD40 PF00400.32 EQB60889.1 - 2.4e-30 104.1 12.8 4.8e-09 36.7 1.3 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB60889.1 - 2.5e-09 37.3 0.2 0.00046 20.4 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EQB60889.1 - 1.5e-06 27.8 0.1 0.032 13.6 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 EQB60889.1 - 0.032 12.9 0.1 0.16 10.6 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SHS2_Rpb7-N PF03876.17 EQB60890.1 - 2.3e-09 37.5 0.0 4.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EQB60890.1 - 2.3e-09 37.4 0.0 4.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain VASP_tetra PF08776.11 EQB60890.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 VASP tetramerisation domain UQ_con PF00179.26 EQB60892.1 - 9.3e-50 167.9 0.1 1.1e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EQB60892.1 - 1.6e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EQB60892.1 - 8.9e-06 26.0 0.1 1.1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 RWD domain PHD_2 PF13831.6 EQB60893.1 - 2.7e-13 49.2 1.0 2.7e-13 49.2 1.0 2.1 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EQB60893.1 - 2.8e-09 37.1 4.7 2.1e-08 34.3 0.2 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 EQB60893.1 - 6e-07 29.3 4.7 6e-07 29.3 4.7 2.7 3 1 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.6 EQB60893.1 - 5e-05 23.0 7.6 0.00019 21.1 7.6 2.0 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EQB60893.1 - 0.00029 20.7 2.9 0.00029 20.7 2.9 2.2 1 1 0 2 2 2 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 EQB60893.1 - 0.0069 16.3 0.6 0.0069 16.3 0.6 2.5 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EQB60893.1 - 0.032 14.3 1.6 0.032 14.3 1.6 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger SLD5_C PF16922.5 EQB60894.1 - 0.0017 18.5 0.2 0.0045 17.1 0.1 1.8 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Herpes_UL82_83 PF05784.11 EQB60894.1 - 0.11 11.3 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus HNH PF01844.23 EQB60895.1 - 0.002 18.3 1.8 0.052 13.7 0.0 2.6 2 0 0 2 2 2 1 HNH endonuclease DUF3364 PF11844.8 EQB60895.1 - 0.014 15.6 0.7 0.06 13.6 0.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3364) PulA_N1 PF17999.1 EQB60895.1 - 0.046 14.5 2.2 8.2 7.3 0.1 3.0 2 0 0 2 2 2 0 Pullulanase N1-terminal domain zf-Di19 PF05605.12 EQB60895.1 - 0.058 13.7 1.9 0.084 13.2 0.4 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rhodanese_C PF12368.8 EQB60895.1 - 0.097 13.1 4.1 0.86 10.0 2.4 2.3 2 0 0 2 2 2 0 Rhodanase C-terminal DUF3546 PF12066.8 EQB60895.1 - 0.62 10.3 7.5 0.17 12.1 2.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3546) zf-C2H2_4 PF13894.6 EQB60895.1 - 1.1 10.3 10.5 0.71 10.9 1.8 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EQB60895.1 - 1.3 9.6 12.3 1.3 9.6 1.7 3.3 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EQB60895.1 - 2.9 8.3 17.3 1.6 9.1 5.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CCB2_CCB4 PF11152.8 EQB60896.1 - 0.17 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 FAM163 PF15069.6 EQB60896.1 - 0.25 11.8 2.1 0.44 11.0 2.1 1.4 1 0 0 1 1 1 0 FAM163 family Ribonuc_red_lgC PF02867.15 EQB60897.1 - 1.4e-49 169.0 0.0 1.7e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EQB60897.1 - 1.2e-20 73.3 0.1 2.1e-20 72.5 0.1 1.4 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuc_red_lgC PF02867.15 EQB60898.1 - 7.6e-66 222.7 0.1 8.9e-66 222.5 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Pneumo_M2 PF07380.11 EQB60898.1 - 0.073 13.4 0.2 0.21 11.8 0.2 1.8 2 0 0 2 2 2 0 Pneumovirus M2 protein TFIIS_C PF01096.18 EQB60899.1 - 3.4e-19 68.4 1.6 3.4e-19 68.4 1.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EQB60899.1 - 3.6e-05 23.5 2.6 3.6e-05 23.5 2.6 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 EQB60899.1 - 0.0042 16.7 3.5 0.023 14.4 3.5 2.2 1 1 1 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain COP-gamma_platf PF08752.10 EQB60899.1 - 0.061 13.4 0.2 0.07 13.3 0.2 1.1 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain PhnA_Zn_Ribbon PF08274.12 EQB60899.1 - 0.069 13.1 5.0 0.62 10.1 0.1 3.7 3 1 1 4 4 4 0 PhnA Zinc-Ribbon Tnp_zf-ribbon_2 PF13842.6 EQB60899.1 - 0.076 13.8 1.4 0.076 13.8 1.4 3.1 3 1 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon zf-RRPl_C4 PF17026.5 EQB60899.1 - 0.2 11.8 11.4 0.28 11.3 11.4 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type GSH_synth_ATP PF03917.17 EQB60901.1 - 2.6e-16 59.4 7.2 1.1e-13 50.7 7.2 2.9 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EQB60901.1 - 2.4e-08 34.4 1.0 1.5e-07 31.8 0.5 2.5 2 1 0 2 2 2 1 Eukaryotic glutathione synthase MCM PF00493.23 EQB60902.1 - 1.7e-91 305.3 1.1 2.9e-91 304.5 1.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EQB60902.1 - 3.6e-28 97.9 0.1 7.1e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EQB60902.1 - 1.6e-21 76.5 0.3 3.9e-21 75.3 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EQB60902.1 - 5.6e-08 32.4 0.0 9.8e-07 28.4 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EQB60902.1 - 4.7e-06 27.1 0.2 1.9e-05 25.2 0.2 2.1 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 EQB60902.1 - 0.00063 19.6 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EQB60902.1 - 0.0026 17.5 0.3 0.072 12.8 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain tRNA_anti-like PF12869.7 EQB60902.1 - 0.07 12.7 0.0 0.75 9.4 0.0 2.5 2 0 0 2 2 2 0 tRNA_anti-like Hydrolase PF00702.26 EQB60903.1 - 1e-08 35.7 0.0 6.4e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EQB60903.1 - 0.00044 20.1 11.3 0.00044 20.1 11.3 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 EQB60904.1 - 8.2e-09 35.6 26.6 0.00011 22.5 1.6 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60904.1 - 1.5e-07 31.1 11.4 8.2e-06 25.5 0.1 3.1 1 1 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 EQB60904.1 - 0.0047 16.5 3.5 0.0065 16.0 3.3 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 EQB60904.1 - 0.045 13.7 3.9 0.054 13.4 3.4 1.4 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 EQB60904.1 - 0.1 12.7 0.1 15 5.7 0.0 3.1 1 1 3 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain NPV_P10 PF05531.12 EQB60904.1 - 0.29 11.6 2.3 0.65 10.5 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein LRR_1 PF00560.33 EQB60904.1 - 9.5 7.2 19.4 1.3e+02 3.8 0.0 5.7 5 2 0 5 5 5 0 Leucine Rich Repeat DUF1749 PF08538.10 EQB60905.1 - 3.2e-21 75.7 0.0 2.5e-17 62.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1749) Ser_hydrolase PF06821.13 EQB60905.1 - 0.00025 20.9 0.0 0.0025 17.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 EQB60905.1 - 0.014 16.0 0.0 0.028 15.0 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EQB60905.1 - 0.019 14.5 0.1 1.4 8.4 0.0 2.4 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase POP1 PF06978.11 EQB60908.1 - 2.8e-11 43.8 10.9 5.5e-06 26.5 6.2 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EQB60908.1 - 1.8e-10 41.0 0.0 5.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain EF-hand_7 PF13499.6 EQB60909.1 - 8e-10 39.0 6.6 1.4e-05 25.4 2.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EQB60909.1 - 6.5e-09 35.5 3.1 1.7e-05 24.6 0.2 3.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 EQB60909.1 - 1.1e-06 28.1 6.7 0.069 13.1 1.0 4.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EQB60909.1 - 2.7e-06 26.5 6.8 0.0049 16.3 1.1 4.7 5 0 0 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.9 EQB60909.1 - 0.002 18.4 1.4 0.22 11.9 0.2 2.4 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF4114 PF13448.6 EQB60909.1 - 0.011 16.5 0.9 0.022 15.6 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4114) Polbeta PF18765.1 EQB60911.1 - 0.0042 17.1 0.8 0.0064 16.6 0.7 1.4 1 1 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Monellin PF09200.10 EQB60911.1 - 0.03 14.2 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Monellin DUF5600 PF18150.1 EQB60911.1 - 0.041 14.5 0.3 0.054 14.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) zf-B_box PF00643.24 EQB60912.1 - 6.7e-10 39.0 17.2 2e-07 31.1 1.4 2.5 2 0 0 2 2 2 2 B-box zinc finger RRF PF01765.19 EQB60912.1 - 0.031 14.2 0.3 0.054 13.5 0.3 1.5 1 0 0 1 1 1 0 Ribosome recycling factor RNA_pol_Rpb4 PF03874.16 EQB60913.1 - 0.014 15.8 0.4 0.018 15.4 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 RNase_J_C PF17770.1 EQB60913.1 - 0.091 13.8 0.4 0.34 12.0 0.1 1.9 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain RT_RNaseH PF17917.1 EQB60915.1 - 6.3e-32 110.0 0.1 2e-31 108.4 0.1 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EQB60915.1 - 2.4e-31 107.8 0.0 5.1e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EQB60915.1 - 9.3e-29 100.5 0.5 1.6e-28 99.8 0.5 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) IcmF_C PF06744.12 EQB60915.1 - 0.0073 15.9 0.3 0.073 12.7 0.0 2.3 1 1 0 2 2 2 1 Type VI secretion protein IcmF C-terminal T4_Rnl2_C PF18043.1 EQB60915.1 - 0.047 13.8 3.4 0.057 13.6 1.1 2.3 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal DUF3850 PF12961.7 EQB60915.1 - 0.051 13.6 0.4 0.15 12.2 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) RVT_1 PF00078.27 EQB60916.1 - 2.2e-21 76.4 1.6 6.2e-18 65.1 0.0 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 EQB60916.1 - 9.6e-18 64.4 0.0 3.6e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EQB60916.1 - 1.6e-13 50.9 0.0 2.8e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 EQB60916.1 - 5e-11 42.5 0.2 1.6e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 EQB60916.1 - 9.2e-08 32.6 0.0 2.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 EQB60916.1 - 9.8e-08 32.2 0.0 2.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EQB60916.1 - 5e-06 27.1 0.0 1.6e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Peptidase_A2B PF12384.8 EQB60916.1 - 2.8e-05 23.7 0.1 0.0001 21.9 0.1 1.9 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.10 EQB60916.1 - 3.8e-05 23.5 0.0 8.9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EQB60916.1 - 0.00092 19.0 0.0 0.0029 17.4 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_thumb PF06817.14 EQB60916.1 - 0.0041 16.9 0.6 0.013 15.3 0.6 1.8 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RT_RNaseH PF17917.1 EQB60917.1 - 8.8e-26 90.2 0.0 2.7e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EQB60917.1 - 1.2e-22 79.9 0.0 3.3e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 EQB60917.1 - 0.00025 20.8 0.7 0.00055 19.7 0.7 1.6 1 0 0 1 1 1 1 Reverse transcriptase thumb domain DUF4635 PF15466.6 EQB60917.1 - 0.046 13.2 0.4 0.19 11.3 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) MLVIN_C PF18697.1 EQB60918.1 - 0.036 14.2 0.1 0.076 13.1 0.1 1.5 1 1 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve PF00665.26 EQB60918.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_1_7 PF13843.6 EQB60920.1 - 2e-27 96.4 0.0 2.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1_7 PF13843.6 EQB60921.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 DUF4261 PF14080.6 EQB60922.1 - 0.28 11.3 4.0 0.3 11.2 0.2 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4261) YopD PF05844.12 EQB60923.1 - 0.065 12.2 4.5 0.073 12.1 4.5 1.2 1 0 0 1 1 1 0 YopD protein Bap31_Bap29_C PF18035.1 EQB60924.1 - 0.0063 16.5 0.5 0.0063 16.5 0.5 2.5 3 0 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 EQB60924.1 - 0.016 15.4 1.3 0.016 15.4 1.3 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 EQB60924.1 - 0.031 14.3 0.7 0.082 12.9 0.5 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-synt_C PF00137.21 EQB60926.1 - 1.1e-05 25.7 24.5 0.00023 21.5 9.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Helicase_C_2 PF13307.6 EQB60927.1 - 6.9e-43 146.8 0.0 1.2e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EQB60927.1 - 7.6e-05 22.5 0.0 0.078 12.7 0.0 2.3 2 0 0 2 2 2 2 Helical and beta-bridge domain eIF-5_eIF-2B PF01873.17 EQB60928.1 - 2e-27 95.4 3.2 3.3e-27 94.7 3.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF3874 PF12990.7 EQB60932.1 - 0.012 15.9 0.1 0.05 13.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) ThrE PF06738.12 EQB60932.1 - 0.27 10.6 0.2 0.33 10.3 0.2 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter RVT_1 PF00078.27 EQB60933.1 - 2.5e-05 23.9 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Type2_restr_D3 PF16902.5 EQB60933.1 - 0.12 12.3 1.0 0.66 9.9 0.3 2.4 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain BsuBI_PstI_RE PF06616.11 EQB60934.1 - 0.00038 19.8 0.4 0.00098 18.4 0.2 1.7 1 1 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain Bunya_G1 PF03557.15 EQB60934.1 - 0.00055 18.1 0.5 0.00072 17.7 0.5 1.2 1 0 0 1 1 1 1 Bunyavirus glycoprotein G1 HSDR_N_2 PF13588.6 EQB60934.1 - 0.019 15.0 2.8 0.024 14.6 1.7 1.9 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Peptidase_M48 PF01435.18 EQB60935.1 - 2.8e-08 33.8 0.0 4.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 EF1G PF00647.19 EQB60935.1 - 0.0015 18.6 3.0 0.0038 17.3 3.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain Ras_bdg_2 PF14847.6 EQB60935.1 - 0.016 15.6 1.3 0.046 14.1 1.3 1.8 1 1 0 1 1 1 0 Ras-binding domain of Byr2 PCI PF01399.27 EQB60936.1 - 7.7e-07 29.6 2.4 1.3e-06 28.9 0.7 2.4 2 1 0 2 2 2 1 PCI domain Spt5-NGN PF03439.13 EQB60937.1 - 8.7e-17 60.8 1.4 1.4e-15 57.0 0.3 3.3 3 1 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section PBP1_TM PF14812.6 EQB60937.1 - 2 8.9 7.0 19 5.7 3.7 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CHAP PF05257.16 EQB60938.1 - 0.017 15.7 0.2 0.032 14.8 0.2 1.6 1 1 0 1 1 1 0 CHAP domain FBPase PF00316.20 EQB60938.1 - 0.042 13.3 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain GlcNAc-1_reg PF18440.1 EQB60939.1 - 0.12 12.6 0.2 0.3 11.4 0.2 1.6 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain CagE_TrbE_VirB PF03135.14 EQB60940.1 - 0.0047 17.1 2.2 1.1 9.3 0.1 2.1 2 0 0 2 2 2 2 CagE, TrbE, VirB family, component of type IV transporter system TraF PF13728.6 EQB60940.1 - 0.008 16.0 0.2 0.18 11.6 0.0 2.2 2 1 0 2 2 2 1 F plasmid transfer operon protein zf-RVT PF13966.6 EQB60940.1 - 0.086 13.6 0.9 0.23 12.2 0.7 1.8 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase zf-RING_7 PF02591.15 EQB60940.1 - 8.2 6.7 7.2 8.6 6.6 1.8 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain RRXRR PF14239.6 EQB60941.1 - 0.068 13.0 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 RRXRR protein gag-asp_proteas PF13975.6 EQB60942.1 - 3.1e-08 34.1 0.0 5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 EQB60942.1 - 3.5e-07 30.5 0.0 6.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EQB60942.1 - 2.8e-05 24.6 0.0 4.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease HEPN_Apea PF18739.1 EQB60944.1 - 6.2 7.3 11.9 0.38 11.2 1.1 2.2 1 1 1 2 2 2 0 Apea-like HEPN AAA_5 PF07728.14 EQB60945.1 - 3.7e-60 201.9 3.1 1.9e-29 102.4 0.0 5.2 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EQB60945.1 - 3.3e-16 59.3 0.0 8.2e-11 41.9 0.0 4.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EQB60945.1 - 3.1e-10 39.9 7.2 7.7e-06 25.5 0.1 3.8 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 EQB60945.1 - 7e-10 39.0 0.2 0.032 14.3 0.0 3.9 3 1 0 3 3 3 3 Dynein heavy chain region D6 P-loop domain AAA_lid_7 PF17867.1 EQB60945.1 - 9.1e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Midasin AAA lid domain Sigma54_activat PF00158.26 EQB60945.1 - 1e-08 35.1 1.7 0.0001 22.0 0.1 3.1 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_6 PF12774.7 EQB60945.1 - 6.3e-08 31.9 8.6 0.066 12.2 0.1 5.1 5 0 0 5 5 5 3 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 EQB60945.1 - 1.3e-06 28.9 4.7 0.0068 16.8 0.1 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EQB60945.1 - 1.4e-06 28.8 2.0 0.07 13.5 0.0 4.2 3 2 0 4 4 4 2 AAA ATPase domain T2SSE PF00437.20 EQB60945.1 - 3.2e-06 26.4 2.4 0.021 13.9 0.3 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EQB60945.1 - 1.3e-05 25.3 0.0 0.0012 19.0 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EQB60945.1 - 2.6e-05 23.7 0.1 0.11 11.9 0.0 4.2 4 1 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EQB60945.1 - 0.00057 20.2 0.1 0.00057 20.2 0.1 3.5 4 1 0 4 4 2 1 AAA domain AAA_lid_5 PF17865.1 EQB60945.1 - 0.00066 19.7 3.2 0.0019 18.3 0.5 2.7 2 0 0 2 2 2 1 Midasin AAA lid domain RsgA_GTPase PF03193.16 EQB60945.1 - 0.00088 19.2 3.3 0.015 15.2 0.3 3.2 2 0 0 2 2 2 1 RsgA GTPase TsaE PF02367.17 EQB60945.1 - 0.0019 18.2 0.1 0.93 9.5 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EQB60945.1 - 0.0025 17.6 0.3 0.082 12.7 0.1 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 EQB60945.1 - 0.011 15.9 0.1 8.3 6.7 0.0 3.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EQB60945.1 - 0.045 13.2 3.7 0.4 10.1 0.1 2.8 3 0 0 3 3 3 0 Bacterial TniB protein IstB_IS21 PF01695.17 EQB60945.1 - 0.069 12.9 0.0 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 EQB60945.1 - 0.13 12.6 2.7 33 4.8 0.0 4.3 5 0 0 5 5 4 0 AAA domain ABC_tran PF00005.27 EQB60945.1 - 0.31 11.6 0.1 0.31 11.6 0.1 4.3 4 0 0 4 4 4 0 ABC transporter AAA_18 PF13238.6 EQB60945.1 - 1.1 9.8 0.0 1.1 9.8 0.0 6.1 5 3 1 6 6 5 0 AAA domain Orf78 PF06024.12 EQB60946.1 - 0.001 19.4 1.7 0.001 19.4 1.7 5.4 1 1 1 2 2 2 1 Orf78 (ac78) Pox_EPC_I2-L1 PF12575.8 EQB60946.1 - 0.12 12.6 2.2 0.5 10.6 2.2 2.1 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 TMEM132D_C PF15706.5 EQB60946.1 - 0.39 10.5 0.1 0.39 10.5 0.1 4.1 1 1 2 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LAP1C PF05609.12 EQB60946.1 - 2.2 7.3 35.7 1.9 7.5 32.3 1.8 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RIFIN PF02009.16 EQB60946.1 - 9.6 6.0 25.4 0.074 12.9 11.5 2.1 1 1 1 2 2 2 0 Rifin MHCassoc_trimer PF08831.10 EQB60947.1 - 0.041 13.9 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain GLTP PF08718.11 EQB60947.1 - 0.043 14.1 0.2 0.046 14.0 0.2 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) DUF1512 PF07431.12 EQB60947.1 - 0.08 11.9 0.0 0.086 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) FAM193_C PF15914.5 EQB60948.1 - 0.016 14.9 1.8 7.4 6.4 0.0 2.9 2 0 0 2 2 2 0 FAM193 family C-terminal Rhabdo_ncap_2 PF03216.13 EQB60949.1 - 0.0064 16.0 0.4 0.0081 15.7 0.4 1.1 1 0 0 1 1 1 1 Rhabdovirus nucleoprotein HEPN_Apea PF18739.1 EQB60949.1 - 0.0093 16.4 0.2 0.01 16.2 0.2 1.1 1 0 0 1 1 1 1 Apea-like HEPN NitrOD5 PF11537.8 EQB60950.1 - 0.038 14.1 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Nitrosopumilus output domain 5 HAD_2 PF13419.6 EQB60953.1 - 9.9e-07 29.0 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EQB60953.1 - 0.002 18.4 0.0 0.0023 18.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EQB60953.1 - 0.023 14.5 0.2 0.032 14.1 0.2 1.3 1 1 0 1 1 1 0 Acid Phosphatase Ribosomal_L30 PF00327.20 EQB60953.1 - 0.07 13.0 0.0 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e Med27 PF11571.8 EQB60954.1 - 0.0014 18.9 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 PNK3P PF08645.11 EQB60954.1 - 0.03 14.0 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase zf-Tim10_DDP PF02953.15 EQB60954.1 - 0.27 10.9 4.7 0.48 10.1 4.7 1.5 1 1 0 1 1 1 0 Tim10/DDP family zinc finger gag-asp_proteas PF13975.6 EQB60955.1 - 1.9e-10 41.1 0.1 6.1e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.8 EQB60955.1 - 6.2e-09 35.6 0.3 6.2e-09 35.6 0.3 1.6 2 0 0 2 2 2 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 EQB60955.1 - 3e-08 34.2 0.0 6.9e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 EQB60955.1 - 2.4e-06 27.4 0.1 4.2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EQB60955.1 - 2.7e-05 24.0 0.2 4.7e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EQB60955.1 - 0.00031 21.0 0.0 0.00082 19.6 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Vac_Fusion PF02346.16 EQB60955.1 - 0.04 13.5 1.5 0.65 9.7 0.2 2.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DASH_Duo1 PF08651.10 EQB60955.1 - 1.5 8.7 5.5 13 5.6 0.4 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 RVT_1 PF00078.27 EQB60956.1 - 7e-06 25.7 0.7 9.5e-06 25.3 0.7 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BRE1 PF08647.11 EQB60960.1 - 0.069 13.2 0.7 0.13 12.4 0.7 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase PhoU PF01895.19 EQB60963.1 - 2.7 8.5 5.7 5.7 7.5 0.1 2.4 2 0 0 2 2 2 0 PhoU domain zinc_ribbon_15 PF17032.5 EQB60964.1 - 4.1e-15 56.3 10.5 8.6e-15 55.3 10.5 1.5 1 1 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 EQB60964.1 - 0.0026 17.7 12.3 0.06 13.4 3.4 2.7 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_12 PF11331.8 EQB60964.1 - 0.015 15.1 0.3 0.015 15.1 0.3 3.6 4 1 1 5 5 5 0 Probable zinc-ribbon domain zinc-ribbon_6 PF10005.9 EQB60964.1 - 0.024 15.3 0.9 0.024 15.3 0.9 2.5 3 0 0 3 3 3 0 zinc-ribbon domain DUF1741 PF08427.10 EQB60965.1 - 0.015 15.0 5.0 0.023 14.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) WD40 PF00400.32 EQB60966.1 - 3.2e-05 24.6 9.3 0.24 12.3 0.3 5.0 4 1 0 4 4 4 2 WD domain, G-beta repeat WD40_like PF17005.5 EQB60966.1 - 0.00021 20.7 0.9 0.00031 20.2 0.9 1.4 1 0 0 1 1 1 1 WD40-like domain PQQ_3 PF13570.6 EQB60966.1 - 0.003 18.0 0.0 0.7 10.5 0.0 2.6 2 0 0 2 2 2 2 PQQ-like domain Kinesin PF00225.23 EQB60967.1 - 2.6e-83 279.7 9.1 2.6e-83 279.7 9.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EQB60967.1 - 3.6e-19 69.2 2.3 3.6e-19 69.2 2.3 3.1 4 1 0 4 4 4 1 Microtubule binding Cnn_1N PF07989.11 EQB60967.1 - 0.004 17.3 9.9 0.004 17.3 9.9 2.8 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 DnaI_N PF07319.11 EQB60967.1 - 0.28 11.9 7.5 0.066 13.9 2.0 2.8 1 1 1 2 2 2 0 Primosomal protein DnaI N-terminus TSC22 PF01166.18 EQB60967.1 - 1 9.7 8.8 0.14 12.5 1.7 3.1 1 1 2 3 3 3 0 TSC-22/dip/bun family HALZ PF02183.18 EQB60967.1 - 1.8 8.9 9.9 38 4.6 1.1 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Binary_toxB_3 PF17476.2 EQB60967.1 - 9.4 6.5 10.0 0.97 9.7 4.3 2.4 3 0 0 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA domain 3 MCRA PF06100.11 EQB60970.1 - 0.066 12.0 0.2 0.075 11.8 0.2 1.0 1 0 0 1 1 1 0 MCRA family LRR_4 PF12799.7 EQB60971.1 - 0.00012 22.3 25.9 0.002 18.5 1.2 6.5 3 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB60971.1 - 0.0009 19.0 13.2 0.25 11.2 3.3 4.7 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 EQB60971.1 - 0.0098 15.9 15.1 45 4.5 0.0 8.4 9 1 1 10 10 10 0 Leucine Rich repeat Cdc6_C PF09079.11 EQB60971.1 - 0.027 14.4 0.8 2.5 8.1 0.0 2.9 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Lip_prot_lig_C PF10437.9 EQB60971.1 - 0.047 13.7 5.1 2.8 8.0 0.1 3.7 3 2 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus SANT_DAMP1_like PF16282.5 EQB60971.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 LRR_1 PF00560.33 EQB60971.1 - 0.098 13.3 20.3 1.6 9.6 0.4 7.1 9 0 0 9 9 9 0 Leucine Rich Repeat Acetyltransf_1 PF00583.25 EQB60972.1 - 4.4e-09 36.6 0.1 5.9e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EQB60972.1 - 4.7e-06 26.6 0.1 6.2e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EQB60972.1 - 7.4e-05 23.1 1.1 0.00013 22.3 1.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EQB60972.1 - 0.023 15.3 0.0 0.03 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EQB60972.1 - 0.092 12.9 5.3 0.096 12.8 4.4 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EQB60972.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 EQB60973.1 - 1.3e-52 178.8 0.0 3.4e-52 177.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB60973.1 - 2.5e-37 128.6 0.0 5.3e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 EQB60973.1 - 3.4e-05 24.0 0.4 9.9e-05 22.5 0.4 1.8 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain LIN52 PF10044.9 EQB60973.1 - 0.84 10.4 3.9 0.66 10.7 0.1 2.8 2 0 0 2 2 2 0 Retinal tissue protein WD40_like PF17005.5 EQB60974.1 - 4.9e-88 295.3 29.2 5.9e-88 295.1 29.2 1.0 1 0 0 1 1 1 1 WD40-like domain Aminotran_1_2 PF00155.21 EQB60975.1 - 5.2e-20 71.9 0.0 6.8e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Arf PF00025.21 EQB60976.1 - 1.6e-18 66.7 0.9 1.8e-18 66.6 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EQB60976.1 - 5.8e-05 22.7 0.2 6.8e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EQB60976.1 - 0.00032 20.0 0.4 0.0005 19.3 0.4 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 EQB60976.1 - 0.00099 19.3 0.2 0.0014 18.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RVT_1 PF00078.27 EQB60977.1 - 5e-33 114.5 2.5 7.7e-33 113.9 2.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flavodoxin_1 PF00258.25 EQB60978.1 - 2.1e-14 54.0 0.0 6.4e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin tRNA-synt_1b PF00579.25 EQB60979.1 - 8.3e-10 38.5 1.3 9.1e-10 38.3 1.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TPR_1 PF00515.28 EQB60980.1 - 2.5e-06 27.1 8.4 0.81 9.6 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EQB60980.1 - 0.00052 20.2 0.2 0.005 17.1 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EQB60980.1 - 0.00055 19.9 1.1 29 5.1 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EQB60980.1 - 0.04 14.4 0.0 8.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EQB60980.1 - 0.091 13.0 3.4 0.93 9.8 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Succ_DH_flav_C PF02910.20 EQB60981.1 - 0.14 12.2 0.5 0.36 10.8 0.5 1.7 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term Ku_PK_bind PF08785.11 EQB60981.1 - 0.3 11.2 6.3 0.68 10.1 0.2 2.9 2 1 0 3 3 3 0 Ku C terminal domain like DUF966 PF06136.13 EQB60982.1 - 6.1 6.5 23.3 7.1 6.2 23.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PCI PF01399.27 EQB60984.1 - 6.4e-08 33.1 0.9 2e-07 31.5 0.9 2.0 1 1 0 1 1 1 1 PCI domain DUF2553 PF10830.8 EQB60987.1 - 0.24 12.2 4.3 2 9.2 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2553) CCDC32 PF14989.6 EQB60987.1 - 0.28 11.2 2.8 0.21 11.6 1.1 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing 32 PcfJ PF14284.6 EQB60990.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 PcfJ-like protein SANTA PF09133.10 EQB60992.1 - 0.0022 18.5 0.0 0.0062 17.0 0.0 1.8 1 0 0 1 1 1 1 SANTA (SANT Associated) PH_4 PF15404.6 EQB60993.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain RVT_1 PF00078.27 EQB60994.1 - 1.8e-26 93.0 0.2 2.6e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GerPE PF10970.8 EQB60995.1 - 0.033 14.4 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Spore germination protein GerPE Linker_histone PF00538.19 EQB60996.1 - 0.0081 16.5 1.5 0.015 15.7 0.3 2.2 2 0 0 2 2 2 1 linker histone H1 and H5 family TraF PF13728.6 EQB60996.1 - 0.039 13.8 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Pro_sub2 PF18513.1 EQB60997.1 - 0.058 13.6 4.6 0.073 13.3 4.1 1.5 1 1 0 1 1 1 0 Prodomain subtilisin 2 TRAM_2 PF18693.1 EQB60999.1 - 0.17 12.1 0.7 17 5.6 0.1 2.6 2 0 0 2 2 2 0 TRAM domain COX7C PF02935.16 EQB61000.1 - 0.049 13.9 0.3 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc GTP_EFTU_D3 PF03143.17 EQB61001.1 - 9.4e-15 54.9 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Glyco_transf_15 PF01793.16 EQB61002.1 - 2.4e-93 313.0 18.3 2.8e-93 312.7 18.3 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase tRNA-synt_1 PF00133.22 EQB61003.1 - 2.2e-152 508.4 11.4 8.6e-54 182.8 0.1 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EQB61003.1 - 8.4e-18 64.8 0.3 2.4e-17 63.3 0.3 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EQB61003.1 - 8.7e-16 57.7 20.3 2.2e-12 46.4 0.1 5.1 5 0 0 5 5 5 3 tRNA synthetases class I (M) Actin PF00022.19 EQB61004.1 - 1.8e-14 53.2 0.7 1.2e-08 34.0 0.0 3.5 2 2 1 3 3 3 3 Actin Dynein_light PF01221.18 EQB61006.1 - 1.2e-13 51.2 0.2 1.8e-13 50.6 0.2 1.4 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 EQB61006.1 - 0.00082 20.0 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Ground-like domain DUF5611 PF18446.1 EQB61006.1 - 0.0072 17.2 0.7 0.017 16.0 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5611) Phage_holin_2_1 PF04971.12 EQB61006.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage P21 holin S MukF_C PF17193.4 EQB61006.1 - 0.14 12.3 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 MukF C-terminal domain AAA_12 PF13087.6 EQB61007.1 - 1.3e-21 77.1 0.9 2.2e-11 43.7 0.2 2.5 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 EQB61007.1 - 1.7e-18 67.4 0.7 1.7e-13 50.9 0.0 2.6 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EQB61007.1 - 3.4e-18 66.3 2.7 4e-17 62.7 2.7 2.0 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EQB61007.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EQB61007.1 - 7.7e-08 32.8 0.0 3.1e-06 27.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EQB61007.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.6 EQB61007.1 - 0.078 12.7 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 EQB61007.1 - 0.27 10.6 9.3 1.9 7.8 0.1 3.0 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain FliO PF04347.13 EQB61008.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO Ribosomal_L2_C PF03947.18 EQB61010.1 - 1.1e-31 109.7 1.7 1.9e-31 108.9 1.1 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EQB61010.1 - 1.9e-05 24.5 0.0 5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Mpp10 PF04006.12 EQB61011.1 - 0.00031 19.3 19.2 0.00036 19.1 19.2 1.0 1 0 0 1 1 1 1 Mpp10 protein Mpp10 PF04006.12 EQB61012.1 - 4.7e-10 38.6 7.1 4.7e-10 38.6 7.1 2.0 1 1 1 2 2 2 1 Mpp10 protein DUF792 PF05632.11 EQB61012.1 - 0.038 13.9 1.7 1.3 8.9 0.1 2.1 1 1 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF792) S100PBPR PF15427.6 EQB61012.1 - 0.27 10.4 5.8 0.35 10.1 5.5 1.4 1 1 0 1 1 1 0 S100P-binding protein NIF PF03031.18 EQB61013.1 - 5.2e-10 39.3 3.9 6.1e-10 39.1 3.9 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF4505 PF14956.6 EQB61013.1 - 0.14 11.9 2.4 0.34 10.6 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4505) SNF2_N PF00176.23 EQB61016.1 - 3.2e-58 197.1 0.5 2.1e-57 194.4 0.2 2.2 1 1 1 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 EQB61016.1 - 2.8e-10 39.9 9.1 1.1e-06 28.5 4.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EQB61016.1 - 3.2e-08 33.8 0.0 1.3e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AT_hook PF02178.19 EQB61016.1 - 0.46 10.5 5.2 0.15 12.0 1.6 2.1 2 0 0 2 2 2 0 AT hook motif NDUF_B12 PF08122.12 EQB61017.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family DDE_Tnp_1_7 PF13843.6 EQB61020.1 - 9.5e-33 113.9 0.1 1.1e-32 113.7 0.1 1.0 1 0 0 1 1 1 1 Transposase IS4 tRNA-synt_1e PF01406.19 EQB61021.1 - 1.7e-68 231.2 23.4 6.2e-59 199.8 4.6 3.0 1 1 1 3 3 3 3 tRNA synthetases class I (C) catalytic domain tRNA-synt_1e PF01406.19 EQB61022.1 - 2.7e-38 132.0 1.2 2.7e-38 132.0 1.2 2.1 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EQB61022.1 - 8.3e-05 21.5 0.8 0.00014 20.8 0.3 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) Herpes_UL79 PF03049.14 EQB61022.1 - 0.024 14.3 0.5 0.42 10.2 0.2 2.1 1 1 1 2 2 2 0 UL79 family TraI_2_C PF07515.11 EQB61026.1 - 0.0071 16.3 0.4 0.011 15.6 0.4 1.3 1 0 0 1 1 1 1 Putative conjugal transfer nickase/helicase TraI C-term DDE_Tnp_1_7 PF13843.6 EQB61027.1 - 3.4e-17 62.8 0.1 5.2e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Transposase IS4 Rab5-bind PF09311.11 EQB61029.1 - 0.031 13.7 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Rabaptin-like protein CYTH PF01928.21 EQB61029.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 CYTH domain Aldo_ket_red PF00248.21 EQB61031.1 - 7.7e-44 150.0 1.1 1.1e-42 146.3 1.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SO_alpha_A3 PF17806.1 EQB61031.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain Aldo_ket_red PF00248.21 EQB61032.1 - 2.2e-35 122.3 0.2 2.6e-35 122.0 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIB PF00382.19 EQB61033.1 - 2.3e-35 120.4 5.0 4.7e-19 68.2 0.7 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EQB61033.1 - 3.1e-11 42.6 5.7 6.1e-11 41.6 5.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 EQB61033.1 - 0.0001 22.3 1.5 0.001 19.1 0.1 2.2 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 EQB61033.1 - 0.00043 20.0 0.1 0.0011 18.7 0.0 1.7 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EQB61033.1 - 0.0045 17.1 0.0 0.015 15.4 0.0 1.7 1 1 0 2 2 2 1 Cyclin, C-terminal domain DUF1289 PF06945.13 EQB61033.1 - 0.11 12.3 3.7 4.8 7.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF643 PF04867.12 EQB61033.1 - 0.17 12.5 4.7 0.21 12.2 0.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF643) Lar_restr_allev PF14354.6 EQB61033.1 - 0.38 11.2 4.4 0.14 12.6 1.2 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar LRR_8 PF13855.6 EQB61034.1 - 6.9e-11 41.7 35.4 3.5e-05 23.5 3.3 4.7 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EQB61034.1 - 0.0021 18.4 48.4 0.0085 16.5 5.8 7.3 3 2 5 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB61034.1 - 0.31 11.7 0.2 0.31 11.7 0.2 7.1 9 2 0 9 9 9 0 Leucine Rich Repeat DUF2513 PF10711.9 EQB61037.1 - 3.3 8.0 7.6 0.28 11.5 1.3 2.4 2 1 1 3 3 3 0 Hypothetical protein (DUF2513) WD40 PF00400.32 EQB61039.1 - 1.1e-12 48.2 9.4 0.073 14.0 0.5 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 EQB61039.1 - 1.1e-05 25.4 0.7 0.0015 18.4 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EQB61039.1 - 0.0023 17.3 6.3 0.0055 16.1 1.2 2.2 1 1 0 1 1 1 1 WD40-like domain DHquinase_I PF01487.15 EQB61039.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Type I 3-dehydroquinase NDK PF00334.19 EQB61042.1 - 7.1e-46 155.6 0.0 7.8e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NOT2_3_5 PF04153.18 EQB61043.1 - 2e-30 105.6 6.7 3.4e-30 104.8 6.7 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family HlyIII PF03006.20 EQB61044.1 - 1.5e-24 87.0 22.7 1.7e-24 86.8 22.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related Tmemb_18A PF09771.9 EQB61044.1 - 2.1 8.8 6.8 0.84 10.1 0.1 2.9 1 1 1 3 3 3 0 Transmembrane protein 188 HEAT_2 PF13646.6 EQB61045.1 - 1.2e-17 64.0 0.0 5e-08 33.2 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 EQB61045.1 - 1.5e-12 46.9 0.0 0.053 14.2 0.0 5.0 5 0 0 5 5 5 3 PBS lyase HEAT-like repeat HEAT PF02985.22 EQB61045.1 - 9e-05 22.4 0.0 3.1 8.3 0.0 4.5 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 EQB61045.1 - 0.0024 17.9 0.0 5.6 7.2 0.0 3.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EQB61045.1 - 0.017 15.6 0.0 34 5.1 0.0 4.0 4 1 1 5 5 5 0 HEAT-like repeat Aconitase_B_N PF11791.8 EQB61045.1 - 0.032 14.3 0.1 0.43 10.6 0.0 2.3 2 1 0 2 2 2 0 Aconitate B N-terminal domain Rap1_C PF11626.8 EQB61045.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Diphthamide_syn PF01866.17 EQB61046.1 - 6.6e-88 295.0 8.2 2.6e-51 174.9 0.0 2.1 1 1 1 2 2 2 2 Putative diphthamide synthesis protein CDT1 PF08839.11 EQB61047.1 - 0.00041 20.7 5.0 0.0011 19.3 5.0 2.0 1 1 0 1 1 1 1 DNA replication factor CDT1 like NUMOD1 PF07453.13 EQB61047.1 - 0.0085 16.3 2.2 0.0085 16.3 2.2 3.9 5 0 0 5 5 5 1 NUMOD1 domain IL28A PF15177.6 EQB61047.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Interleukin-28A Sld5 PF05916.11 EQB61051.1 - 6.5e-08 33.0 1.3 9.5e-08 32.5 0.6 1.6 2 0 0 2 2 2 1 GINS complex protein VTC PF09359.10 EQB61052.1 - 1.6e-76 257.3 11.1 1.6e-76 257.3 11.1 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EQB61052.1 - 2.6e-12 47.0 3.6 4.4e-12 46.3 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 EQB61052.1 - 0.018 15.0 14.8 1.8 8.4 1.4 3.4 2 1 1 3 3 3 0 SPX domain VTC PF09359.10 EQB61053.1 - 4.5e-40 137.8 1.0 6.6e-40 137.2 1.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EQB61053.1 - 1.5e-12 47.8 3.6 2.3e-12 47.2 3.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) WD40_alt PF14077.6 EQB61053.1 - 0.055 13.3 0.5 0.18 11.7 0.5 1.9 1 0 0 1 1 1 0 Alternative WD40 repeat motif DivIC PF04977.15 EQB61053.1 - 0.58 10.0 3.7 0.42 10.4 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator TPR_1 PF00515.28 EQB61054.1 - 1.3e-16 59.6 33.9 0.00011 21.9 0.2 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EQB61054.1 - 4.3e-15 54.5 17.9 0.0034 17.4 0.0 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EQB61054.1 - 9e-15 53.6 37.4 0.00046 20.2 0.7 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EQB61054.1 - 5.3e-09 36.3 1.5 0.074 13.3 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EQB61054.1 - 1.2e-08 34.5 15.0 1.7e-05 24.4 1.9 5.4 2 1 3 5 5 5 3 TPR repeat TPR_17 PF13431.6 EQB61054.1 - 1.3e-06 28.3 10.6 0.77 10.3 0.1 6.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EQB61054.1 - 2.1e-05 24.2 6.3 11 6.3 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EQB61054.1 - 0.00016 22.2 0.0 4.6 8.3 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat DUF3856 PF12968.7 EQB61054.1 - 0.028 14.5 0.1 1.2 9.2 0.0 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 EQB61054.1 - 0.17 12.4 0.0 9.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 EQB61055.1 - 2.7e-38 131.5 0.2 6.2e-38 130.3 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EQB61055.1 - 2.3e-12 47.2 0.0 5.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EQB61055.1 - 8e-05 22.7 0.1 0.00067 19.7 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EQB61055.1 - 0.00014 21.3 0.3 0.00038 19.9 0.2 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Peptidase_U32_C PF16325.5 EQB61055.1 - 0.008 16.4 0.1 0.043 14.1 0.1 2.2 2 0 0 2 2 2 1 Peptidase family U32 C-terminal domain ABC_tran PF00005.27 EQB61055.1 - 0.076 13.5 0.1 4.9 7.7 0.0 2.9 2 1 1 3 3 3 0 ABC transporter AAA_29 PF13555.6 EQB61055.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cadherin_2 PF08266.12 EQB61055.1 - 0.3 10.9 3.7 0.37 10.6 0.4 2.6 1 1 1 2 2 2 0 Cadherin-like Ribosomal_S26e PF01283.19 EQB61056.1 - 9.3e-36 122.6 8.1 9.9e-36 122.5 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e GerPE PF10970.8 EQB61057.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Spore germination protein GerPE FKBP_N PF01346.18 EQB61057.1 - 0.23 12.4 2.2 0.49 11.4 0.2 2.5 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase RVT_1 PF00078.27 EQB61058.1 - 1.2e-13 51.1 0.0 2.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-AN1 PF01428.16 EQB61059.1 - 2.2e-08 34.1 15.5 3.3e-08 33.6 15.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger RHD_DNA_bind PF00554.22 EQB61059.1 - 0.091 12.7 4.1 0.11 12.4 3.7 1.3 1 1 0 1 1 1 0 Rel homology DNA-binding domain Ssl1 PF04056.14 EQB61060.1 - 8.6e-21 74.6 0.0 3.7e-20 72.5 0.0 1.8 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EQB61060.1 - 0.0071 16.6 19.2 0.0071 16.6 19.2 2.9 2 1 0 2 2 2 1 TFIIH C1-like domain Helicase_C PF00271.31 EQB61062.1 - 3.7e-11 43.4 0.8 3.7e-11 43.4 0.8 2.8 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EQB61062.1 - 2.8e-08 33.7 1.9 3.8e-08 33.3 0.3 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 EQB61062.1 - 0.00048 20.2 1.1 0.00048 20.2 1.1 3.0 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 EQB61062.1 - 0.00096 19.7 0.3 0.0057 17.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EQB61062.1 - 0.0029 17.5 1.5 0.016 15.1 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_19 PF13245.6 EQB61062.1 - 0.0055 17.0 0.9 0.034 14.5 0.9 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EQB61062.1 - 0.0065 16.0 1.5 0.033 13.7 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region T2SSE PF00437.20 EQB61062.1 - 0.011 14.9 1.1 0.018 14.1 0.2 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 EQB61062.1 - 0.013 15.5 0.8 0.013 15.5 0.8 3.5 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EQB61062.1 - 0.02 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EQB61062.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EQB61062.1 - 0.025 14.3 0.1 0.087 12.6 0.1 2.0 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EQB61062.1 - 0.026 14.8 0.3 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EQB61062.1 - 0.031 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_23 PF13476.6 EQB61062.1 - 0.046 14.2 0.1 0.046 14.2 0.1 2.4 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.13 EQB61062.1 - 0.051 12.7 1.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF359 PF04019.12 EQB61062.1 - 0.054 13.1 0.6 0.14 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF359) Sigma54_activat PF00158.26 EQB61062.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 EQB61062.1 - 1.4 8.7 8.1 14 5.4 8.1 2.4 1 1 0 1 1 1 0 AAA domain DHHC PF01529.20 EQB61063.1 - 2.3e-27 95.7 14.7 2.3e-27 95.7 14.7 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase GPR15L PF15854.5 EQB61063.1 - 1.8 8.8 8.6 4 7.7 0.8 2.6 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 DNA_pol_D_N PF18018.1 EQB61064.1 - 2.4e-13 50.3 0.4 4.1e-13 49.6 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EQB61064.1 - 1.2e-12 47.7 1.3 6.9e-09 35.4 0.3 2.8 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B XRN_M PF17846.1 EQB61065.1 - 5.7e-41 140.9 5.1 6.6e-41 140.7 5.1 1.0 1 0 0 1 1 1 1 Xrn1 helical domain ERp29_N PF07912.13 EQB61065.1 - 0.034 14.3 1.0 0.51 10.5 0.1 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain Coilin_N PF15862.5 EQB61065.1 - 0.083 12.7 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus XRN_N PF03159.18 EQB61066.1 - 7.6e-66 222.0 0.5 9e-66 221.7 0.5 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DctP PF03480.13 EQB61066.1 - 0.03 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 SKN1 PF03935.15 EQB61067.1 - 0.01 14.3 1.3 0.01 14.3 1.3 1.9 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) TM1586_NiRdase PF14512.6 EQB61067.1 - 0.44 10.1 9.1 0.39 10.3 8.1 1.5 1 1 0 1 1 1 0 Putative TM nitroreductase Zip PF02535.22 EQB61068.1 - 1.9e-15 56.9 31.4 1.5e-08 34.3 6.2 3.0 1 1 2 3 3 3 3 ZIP Zinc transporter DUF5336 PF17270.2 EQB61068.1 - 0.051 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5336) FAM163 PF15069.6 EQB61068.1 - 0.075 13.5 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 FAM163 family NDUF_B12 PF08122.12 EQB61068.1 - 0.16 12.1 3.9 9.3 6.4 0.0 3.6 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family Zip PF02535.22 EQB61069.1 - 2.2e-17 63.3 11.9 2e-15 56.8 11.9 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4227 PF14004.6 EQB61069.1 - 1.2 9.2 4.8 13 5.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) MutL_C PF08676.11 EQB61071.1 - 1e-09 38.3 0.2 6e-09 35.8 0.1 1.9 1 1 1 2 2 2 2 MutL C terminal dimerisation domain DNApol3-delta_C PF09115.10 EQB61072.1 - 0.023 15.2 2.0 0.046 14.2 1.7 1.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal ATP-gua_Ptrans PF00217.19 EQB61073.1 - 0.015 14.8 0.1 0.042 13.3 0.1 1.7 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Membralin PF09746.9 EQB61075.1 - 9.5 5.1 14.1 12 4.8 14.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein Helicase_C_3 PF13625.6 EQB61077.1 - 1.1e-11 45.0 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EQB61078.1 - 0.00015 21.8 0.0 0.00016 21.7 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EQB61078.1 - 0.04 12.6 0.1 0.042 12.6 0.1 1.0 1 0 0 1 1 1 0 SNF2 family N-terminal domain Sigma54_activat PF00158.26 EQB61078.1 - 0.1 12.3 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain ERCC3_RAD25_C PF16203.5 EQB61079.1 - 7.3e-64 215.3 0.1 8e-64 215.2 0.1 1.0 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C PF00271.31 EQB61079.1 - 9.8e-14 51.6 0.0 1.1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EQB61080.1 - 3.2e-15 56.0 0.1 3.4e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Metallophos PF00149.28 EQB61081.1 - 8e-22 78.7 0.4 1.1e-21 78.3 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EQB61081.1 - 0.021 15.2 0.4 0.052 14.0 0.4 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain HAD_2 PF13419.6 EQB61082.1 - 4.2e-06 27.0 0.9 6.1e-06 26.4 0.9 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EQB61082.1 - 0.0065 16.8 0.0 3.5 7.9 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EQB61082.1 - 0.0069 15.9 0.9 0.17 11.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) Hydrolase_like PF13242.6 EQB61082.1 - 0.045 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Acid_PPase PF12689.7 EQB61082.1 - 0.046 13.6 1.3 4.2 7.2 0.1 2.4 2 1 0 2 2 2 0 Acid Phosphatase IP_trans PF02121.18 EQB61083.1 - 5.7e-09 35.9 9.0 0.00054 19.6 1.6 2.9 1 1 2 3 3 3 3 Phosphatidylinositol transfer protein S4 PF01479.25 EQB61084.1 - 0.00056 19.6 0.0 0.0015 18.2 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EQB61084.1 - 0.061 14.2 0.4 0.097 13.6 0.4 1.7 1 1 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 EQB61085.1 - 7e-39 131.8 2.9 7e-39 131.8 2.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Brr6_like_C_C PF10104.9 EQB61086.1 - 4.1e-23 81.6 8.0 4.1e-23 81.6 8.0 1.5 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Pre-PUA PF17832.1 EQB61087.1 - 0.065 13.9 2.3 0.24 12.1 2.3 1.9 1 1 0 1 1 1 0 Pre-PUA-like domain MbeD_MobD PF04899.12 EQB61087.1 - 0.12 12.5 0.2 1.1 9.4 0.3 2.0 2 0 0 2 2 2 0 MbeD/MobD like Phage_HK97_TLTM PF06120.11 EQB61087.1 - 0.36 10.0 6.0 0.45 9.7 6.0 1.0 1 0 0 1 1 1 0 Tail length tape measure protein PI_PP_I PF18363.1 EQB61087.1 - 1.3 9.3 6.3 2.4 8.4 3.1 2.3 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain 6PGD PF00393.19 EQB61088.1 - 4e-90 302.1 1.2 5.3e-90 301.7 1.2 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EQB61088.1 - 1.4e-38 132.6 0.0 3.1e-38 131.4 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EQB61088.1 - 2.3e-07 31.0 0.1 7.3e-07 29.3 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EQB61088.1 - 1.1e-06 29.1 0.0 3.5e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EQB61088.1 - 0.00024 21.1 0.0 0.00068 19.7 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EQB61088.1 - 0.00067 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EQB61088.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EQB61088.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EQB61088.1 - 0.011 15.4 0.2 0.035 13.8 0.1 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EQB61088.1 - 0.17 12.2 0.3 1.3 9.3 0.0 2.5 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SGS PF05002.15 EQB61091.1 - 1.2e-19 70.2 1.9 2.2e-19 69.4 1.9 1.4 1 0 0 1 1 1 1 SGS domain RRM_2 PF04059.12 EQB61092.1 - 1.5e-38 130.9 2.8 1.5e-38 130.9 2.8 1.6 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 EQB61092.1 - 8.5e-05 22.3 0.2 0.00016 21.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EQB61092.1 - 0.0035 17.5 1.4 0.0055 16.9 0.6 1.7 1 1 0 1 1 1 1 BRCA1-associated protein 2 DCP1 PF06058.13 EQB61093.1 - 1.4e-11 44.3 0.5 1.8e-11 44.0 0.5 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Pkinase PF00069.25 EQB61094.1 - 1.3e-61 208.3 0.5 1.6e-61 208.0 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61094.1 - 1.5e-39 135.8 0.0 3e-39 134.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB61094.1 - 0.0011 18.4 0.0 0.0075 15.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EQB61094.1 - 0.0016 17.9 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EQB61094.1 - 0.026 14.2 0.5 4.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EQB61094.1 - 0.11 11.3 0.3 0.14 10.9 0.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EQB61094.1 - 0.54 9.1 10.3 0.88 8.4 4.8 2.8 2 1 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 EQB61095.1 - 7.1e-19 68.2 0.0 9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61095.1 - 9e-07 28.4 0.0 2.1e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SPASM PF13186.6 EQB61095.1 - 0.14 12.7 1.1 0.75 10.4 0.2 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Ribosomal_L7Ae PF01248.26 EQB61096.1 - 4.5e-12 45.5 0.1 6e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EQB61096.1 - 0.0021 18.1 0.0 0.0024 18.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF4939 PF16297.5 EQB61096.1 - 0.062 13.2 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) DASH_Duo1 PF08651.10 EQB61096.1 - 0.087 12.6 0.6 0.24 11.2 0.2 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 EIF_2_alpha PF07541.12 EQB61097.1 - 3.5e-19 69.0 0.1 5.1e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit TERF2_RBM PF16772.5 EQB61097.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif S-methyl_trans PF02574.16 EQB61097.1 - 0.037 13.9 0.0 0.04 13.7 0.0 1.1 1 0 0 1 1 1 0 Homocysteine S-methyltransferase GH97_N PF14508.6 EQB61097.1 - 0.055 13.0 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 N-terminal Corona_NSP4_C PF16348.5 EQB61098.1 - 0.012 16.4 3.5 3.9 8.3 0.4 2.8 1 1 0 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus JIP_LZII PF16471.5 EQB61098.1 - 0.12 12.5 8.9 1.1 9.4 0.4 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1796 PF08795.10 EQB61098.1 - 0.58 10.1 7.3 3.4 7.6 0.1 2.3 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) BST2 PF16716.5 EQB61098.1 - 1.1 9.9 8.8 1.4 9.6 5.5 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 EQB61098.1 - 2.7 7.8 13.4 0.8 9.5 3.4 3.2 3 0 0 3 3 3 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 EQB61098.1 - 2.9 8.1 16.6 0.093 13.0 5.6 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 EQB61098.1 - 6.7 6.8 19.7 17 5.4 19.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 EQB61098.1 - 9.6 6.5 11.3 5.3 7.4 0.5 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper FAM72 PF14976.6 EQB61099.1 - 2.4e-30 105.6 4.9 2.8e-30 105.4 4.9 1.0 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 EQB61099.1 - 0.49 10.6 7.8 1.3 9.3 7.9 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Mer2 PF09074.10 EQB61100.1 - 0.00035 20.4 4.8 0.00062 19.6 4.8 1.3 1 0 0 1 1 1 1 Mer2 MAP65_ASE1 PF03999.12 EQB61100.1 - 0.4 9.3 10.2 1.1 7.9 0.5 2.8 2 1 1 3 3 3 0 Microtubule associated protein (MAP65/ASE1 family) PAZ PF02170.22 EQB61101.1 - 0.078 12.8 3.6 0.065 13.0 0.6 2.1 2 0 0 2 2 2 0 PAZ domain Hydrolase PF00702.26 EQB61102.1 - 6.7e-05 23.3 0.0 8.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EQB61102.1 - 8.5e-05 22.6 0.2 0.00023 21.2 0.2 1.8 1 1 0 1 1 1 1 Cation transport ATPase (P-type) rve PF00665.26 EQB61103.1 - 0.035 14.3 0.0 0.083 13.1 0.0 1.6 2 0 0 2 2 2 0 Integrase core domain rve_3 PF13683.6 EQB61103.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain MLVIN_C PF18697.1 EQB61103.1 - 0.085 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Cpn10 PF00166.21 EQB61103.1 - 0.13 12.3 0.1 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit GerPE PF10970.8 EQB61104.1 - 0.026 14.7 0.1 0.049 13.8 0.1 1.5 1 1 1 2 2 2 0 Spore germination protein GerPE FKBP_N PF01346.18 EQB61104.1 - 0.11 13.5 2.0 0.87 10.6 0.0 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase FANCI_HD2 PF14680.6 EQB61104.1 - 0.13 11.5 7.3 0.11 11.7 1.0 2.1 1 1 1 2 2 2 0 FANCI helical domain 2 Ant_C PF05586.11 EQB61104.1 - 0.23 12.1 1.9 3.4 8.3 0.1 2.3 1 1 0 2 2 2 0 Anthrax receptor C-terminus region PH_17 PF18012.1 EQB61105.1 - 0.15 11.8 0.0 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 PH domain Proteasome PF00227.26 EQB61106.1 - 7e-37 126.8 0.0 7.9e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CDC45 PF02724.14 EQB61107.1 - 0.0066 14.8 6.0 0.0095 14.3 6.0 1.2 1 0 0 1 1 1 1 CDC45-like protein CPSF100_C PF13299.6 EQB61107.1 - 0.04 14.1 5.1 0.08 13.1 5.1 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AP3D1 PF06375.11 EQB61107.1 - 0.44 10.8 19.7 0.3 11.3 13.2 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Connexin PF00029.19 EQB61107.1 - 0.51 10.1 6.6 0.98 9.1 6.6 1.5 1 0 0 1 1 1 0 Connexin Zip PF02535.22 EQB61107.1 - 1.3 8.1 7.6 2.4 7.3 7.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4820 PF16091.5 EQB61107.1 - 1.5 8.1 10.2 2.9 7.2 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 EQB61107.1 - 2.9 7.6 8.8 5.8 6.6 8.8 1.5 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.15 EQB61107.1 - 3.1 8.4 5.6 0.76 10.4 1.8 1.9 2 0 0 2 2 2 0 Ctr copper transporter family PRC2_HTH_1 PF18118.1 EQB61107.1 - 4.4 8.2 15.4 0.61 10.9 10.4 2.1 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Coilin_N PF15862.5 EQB61107.1 - 6.8 6.5 19.2 13 5.6 18.5 1.8 2 0 0 2 2 2 0 Coilin N-terminus E1-E2_ATPase PF00122.20 EQB61108.1 - 1.8e-21 76.5 0.1 5.2e-21 75.0 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EQB61108.1 - 1.1e-18 68.3 0.0 5.5e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EQB61108.1 - 2.6e-09 37.0 0.5 8.3e-09 35.4 0.5 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF1896 PF08989.10 EQB61108.1 - 0.0099 16.0 2.0 0.54 10.4 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1896) Hydrolase_3 PF08282.12 EQB61108.1 - 0.015 15.0 13.5 0.69 9.6 0.6 4.2 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase DUF2408 PF10303.9 EQB61109.1 - 0.0046 17.5 1.3 0.0046 17.5 1.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Osmo_CC PF08946.10 EQB61109.1 - 0.0083 16.4 4.5 0.02 15.2 4.5 1.6 1 0 0 1 1 1 1 Osmosensory transporter coiled coil Sec1 PF00995.23 EQB61111.1 - 1.9e-29 103.3 19.6 1.3e-28 100.6 19.6 1.9 1 1 0 1 1 1 1 Sec1 family UCR_UQCRX_QCR9 PF05365.12 EQB61113.1 - 7.9 6.5 7.9 0.24 11.4 1.3 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF1182 PF06681.13 EQB61115.1 - 0.011 15.3 0.2 0.012 15.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) MCRS_N PF13325.6 EQB61117.1 - 0.015 15.3 0.4 0.019 15.0 0.4 1.1 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DDE_Tnp_1_7 PF13843.6 EQB61118.1 - 1.1e-23 84.2 0.4 1.3e-23 83.8 0.4 1.1 1 0 0 1 1 1 1 Transposase IS4 PX PF00787.24 EQB61119.1 - 1.2e-11 44.5 1.6 1.5e-11 44.3 1.6 1.1 1 0 0 1 1 1 1 PX domain TMEM154 PF15102.6 EQB61122.1 - 0.19 11.6 0.1 0.19 11.6 0.1 3.6 3 2 1 4 4 4 0 TMEM154 protein family BatA PF07584.11 EQB61122.1 - 2.7 8.4 12.8 3.2 8.2 5.7 3.0 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal AC_N PF16214.5 EQB61122.1 - 3.9 6.5 10.5 1.9 7.5 8.4 1.6 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF3923 PF13061.6 EQB61123.1 - 0.058 13.5 1.1 0.058 13.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Mod_r PF07200.13 EQB61126.1 - 0.00097 19.3 8.7 0.0012 19.0 8.7 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HrcA PF01628.21 EQB61126.1 - 0.03 14.2 1.6 0.034 14.1 1.2 1.3 1 1 0 1 1 1 0 HrcA protein C terminal domain Med28 PF11594.8 EQB61126.1 - 0.05 13.7 5.5 0.063 13.4 5.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 28 Baculo_PEP_C PF04513.12 EQB61126.1 - 0.06 13.4 5.4 0.12 12.5 5.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M15_2 PF05951.13 EQB61126.1 - 0.094 12.4 1.4 0.11 12.1 1.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) CRR7 PF12095.8 EQB61126.1 - 0.48 10.9 3.2 3.3 8.2 0.1 2.7 1 1 2 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Med4 PF10018.9 EQB61126.1 - 4 7.1 7.8 1.3 8.7 5.2 1.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RNA_pol_A_bac PF01000.26 EQB61128.1 - 5.2e-22 78.3 0.0 1e-20 74.2 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EQB61128.1 - 1.1e-11 44.0 0.0 1.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MTS PF05175.14 EQB61129.1 - 5e-06 26.2 0.2 1.8e-05 24.4 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Eco57I PF07669.11 EQB61129.1 - 0.043 14.3 0.3 0.076 13.5 0.3 1.4 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Piwi PF02171.17 EQB61131.1 - 8.1e-85 284.7 0.8 7e-84 281.6 1.1 2.1 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 EQB61131.1 - 1e-12 48.1 0.9 2.8e-12 46.6 0.9 1.8 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 EQB61131.1 - 1.1e-08 35.8 0.4 3.8e-08 34.1 0.4 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EQB61131.1 - 0.0024 18.2 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 EQB61131.1 - 0.047 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Argonaute linker 1 domain ArgoMid PF16487.5 EQB61131.1 - 0.63 10.3 2.6 0.88 9.9 0.3 2.6 2 1 1 3 3 3 0 Mid domain of argonaute IcmF_C PF06744.12 EQB61132.1 - 0.0006 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal BsuBI_PstI_RE PF06616.11 EQB61133.1 - 0.012 14.9 0.1 0.016 14.5 0.1 1.5 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain HSDR_N_2 PF13588.6 EQB61133.1 - 0.037 14.0 0.3 0.064 13.3 0.3 1.6 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) PPTA PF01239.22 EQB61135.1 - 3.5e-07 29.7 10.1 0.0027 17.4 0.2 5.3 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 EQB61135.1 - 0.12 12.8 0.8 0.49 10.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ubiquitin PF00240.23 EQB61136.1 - 1.8e-34 117.3 0.7 3.5e-34 116.4 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EQB61136.1 - 2.7e-16 59.2 1.0 3.9e-16 58.7 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.19 EQB61136.1 - 5.2e-09 36.1 1.1 5.2e-09 36.1 1.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Ubiquitin_2 PF14560.6 EQB61136.1 - 6.8e-06 26.5 0.1 3e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EQB61136.1 - 0.0016 18.6 0.1 0.0035 17.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EQB61136.1 - 0.0042 17.0 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EQB61136.1 - 0.0055 16.7 1.3 1.2 9.2 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EQB61136.1 - 0.0062 16.9 0.2 0.011 16.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EQB61136.1 - 0.013 16.0 0.1 0.017 15.6 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2318 PF10080.9 EQB61136.1 - 0.03 14.4 1.0 0.059 13.5 1.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Phosphodiest PF01663.22 EQB61137.1 - 3.8e-12 46.5 0.0 6.4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EQB61137.1 - 0.00045 19.7 0.0 0.00095 18.6 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EQB61137.1 - 0.002 17.6 0.8 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 Sulfatase PglZ PF08665.12 EQB61137.1 - 0.014 15.4 2.8 0.3 11.1 0.1 3.2 3 0 0 3 3 3 0 PglZ domain Ribosomal_L29 PF00831.23 EQB61137.1 - 0.052 13.5 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal L29 protein DUF3819 PF12842.7 EQB61138.1 - 2.1e-06 27.7 0.1 6.4e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EQB61139.1 - 1.7e-10 40.4 0.9 2e-10 40.2 0.9 1.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EQB61140.1 - 8.1e-15 55.2 3.3 8.1e-15 55.2 3.3 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat ARL2_Bind_BART PF11527.8 EQB61140.1 - 0.22 11.6 9.2 3 8.0 0.1 3.2 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART YmgB PF10798.8 EQB61140.1 - 1.4 8.8 6.6 1.9 8.4 1.6 3.2 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Urm1 PF09138.11 EQB61141.1 - 0.1 13.0 2.3 0.27 11.6 2.0 1.8 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) Pyr_redox_2 PF07992.14 EQB61142.1 - 1.1e-11 44.6 0.0 9.9e-09 34.8 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EQB61142.1 - 2.8e-07 30.1 3.1 0.14 11.4 0.1 3.5 1 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EQB61142.1 - 2.8e-07 31.0 0.4 8.7e-05 23.0 0.0 3.0 3 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EQB61142.1 - 5.8e-06 26.4 0.0 0.0064 16.5 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EQB61142.1 - 8.3e-06 26.0 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EQB61142.1 - 2.8e-05 23.0 2.2 0.001 17.9 0.0 2.4 2 1 0 2 2 2 2 HI0933-like protein FMO-like PF00743.19 EQB61142.1 - 0.00077 18.0 0.2 0.014 13.9 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 EQB61142.1 - 0.0011 18.3 0.0 0.0013 18.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EQB61142.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 EQB61142.1 - 0.0017 18.8 0.0 0.31 11.5 0.0 2.3 1 1 1 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EQB61142.1 - 0.072 12.4 0.0 0.77 9.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Csm4_C PF17953.1 EQB61143.1 - 0.023 14.6 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain ATP-synt_ab PF00006.25 EQB61145.1 - 3.5e-108 360.2 0.0 4.9e-108 359.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EQB61145.1 - 6.4e-40 135.8 0.0 1.2e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EQB61145.1 - 4.2e-12 46.4 1.1 9.2e-12 45.3 1.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Cul7 PF11515.8 EQB61145.1 - 6.5 7.1 6.0 1.9 8.8 0.2 3.0 3 1 1 4 4 4 0 Mouse development and cellular proliferation protein Cullin-7 TIP49 PF06068.13 EQB61146.1 - 1.5e-48 165.8 9.0 1.5e-48 165.8 9.0 2.1 2 1 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EQB61146.1 - 3.8e-11 42.9 1.0 3.8e-11 42.9 1.0 3.3 4 0 0 4 4 4 1 TIP49 AAA-lid domain Streptin-Immun PF11083.8 EQB61147.1 - 0.025 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Desulfoferrod_N PF06397.12 EQB61147.1 - 0.11 12.1 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain ABC_tran PF00005.27 EQB61149.1 - 3.2e-31 108.7 0.1 6.4e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EQB61149.1 - 4e-17 62.8 17.2 6.6e-17 62.0 16.7 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EQB61149.1 - 1.1e-07 31.5 8.6 3.3e-06 26.7 8.6 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EQB61149.1 - 3.6e-06 27.0 6.9 0.012 15.4 2.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EQB61149.1 - 8.4e-05 22.5 1.4 0.00018 21.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EQB61149.1 - 0.00096 19.2 1.3 0.0022 18.1 0.3 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase SHNi-TPR PF10516.9 EQB61149.1 - 0.0085 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR AAA_29 PF13555.6 EQB61149.1 - 0.012 15.3 0.1 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 EQB61149.1 - 0.016 15.4 0.2 0.23 11.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EQB61149.1 - 0.027 14.8 0.0 0.054 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain KH_2 PF07650.17 EQB61149.1 - 0.039 13.8 0.5 0.16 11.8 0.5 2.1 1 0 0 1 1 1 0 KH domain AAA_7 PF12775.7 EQB61149.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region K1377 PF15352.6 EQB61149.1 - 0.077 11.3 1.4 0.12 10.6 1.4 1.2 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy AAA_23 PF13476.6 EQB61149.1 - 4.4 7.7 9.8 3.6 8.0 6.3 2.5 2 1 0 2 2 2 0 AAA domain Sin_N PF04801.13 EQB61150.1 - 0.0055 16.0 1.3 0.0065 15.7 1.3 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region TAF8_C PF10406.9 EQB61151.1 - 1.1e-12 48.2 0.5 1.8e-12 47.6 0.5 1.3 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Uso1_p115_C PF04871.13 EQB61152.1 - 0.0073 16.7 6.5 0.0073 16.7 6.5 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2291 PF10054.9 EQB61152.1 - 0.032 13.9 0.2 0.038 13.7 0.2 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) DUF1299 PF06975.11 EQB61152.1 - 0.057 13.5 3.2 0.16 12.1 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) DUF4407 PF14362.6 EQB61152.1 - 0.1 11.9 5.4 0.13 11.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ferritin-like PF12902.7 EQB61152.1 - 0.13 12.1 3.4 0.14 12.0 3.4 1.1 1 0 0 1 1 1 0 Ferritin-like IFT57 PF10498.9 EQB61152.1 - 0.23 10.4 17.8 0.25 10.2 17.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Tup_N PF08581.10 EQB61152.1 - 0.49 10.7 17.7 0.2 12.0 1.7 2.8 1 1 2 3 3 3 0 Tup N-terminal GRDP-like PF07173.12 EQB61152.1 - 0.51 11.0 8.5 0.76 10.4 8.5 1.4 1 1 0 1 1 1 0 Glycine-rich domain-containing protein-like PI3K_P85_iSH2 PF16454.5 EQB61152.1 - 0.57 9.8 22.0 1.3 8.6 0.8 3.0 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Baculo_PEP_C PF04513.12 EQB61152.1 - 0.67 10.0 9.7 0.079 13.0 2.7 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 EQB61152.1 - 0.82 8.7 19.0 0.64 9.0 16.3 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3490 PF11995.8 EQB61152.1 - 1.3 8.8 13.2 0.33 10.7 6.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3490) Sec2p PF06428.11 EQB61152.1 - 1.7 8.7 16.2 1.4 9.0 6.4 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Lectin_N PF03954.14 EQB61152.1 - 2 8.2 9.4 0.9 9.3 1.0 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 EQB61152.1 - 2 7.6 16.4 0.73 9.0 11.4 1.8 1 1 1 2 2 2 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 EQB61152.1 - 2.7 8.7 12.1 1.9 9.1 2.2 2.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 EQB61152.1 - 5.7 6.4 10.2 7.1 6.1 10.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YtxH PF12732.7 EQB61152.1 - 9.6 6.8 6.4 7.9 7.1 0.8 2.5 1 1 1 2 2 2 0 YtxH-like protein RNA_pol_Rpb2_1 PF04563.15 EQB61153.1 - 6.7e-51 172.7 1.2 1.7e-50 171.3 1.2 1.7 1 0 0 1 1 1 1 RNA polymerase beta subunit ABC_tran PF00005.27 EQB61153.1 - 1.2e-28 100.3 0.2 3.1e-28 99.0 0.2 1.7 1 0 0 1 1 1 1 ABC transporter RNA_pol_Rpb2_2 PF04561.14 EQB61153.1 - 8.5e-17 61.4 2.8 1.9e-16 60.3 2.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 ABC_membrane PF00664.23 EQB61153.1 - 3.5e-13 49.8 9.3 6e-13 49.1 9.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.6 EQB61153.1 - 7.2e-05 22.7 2.6 7.2e-05 22.7 2.6 3.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 EQB61153.1 - 0.00024 20.4 0.1 0.00039 19.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 EQB61153.1 - 0.0024 17.6 0.1 0.0056 16.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EQB61153.1 - 0.0038 16.8 0.1 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EQB61153.1 - 0.016 15.1 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Yip1 PF04893.17 EQB61153.1 - 0.021 14.5 1.1 0.042 13.6 1.1 1.4 1 0 0 1 1 1 0 Yip1 domain AAA_18 PF13238.6 EQB61153.1 - 0.056 14.0 0.1 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EQB61153.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2157 PF09925.9 EQB61153.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) SMC_N PF02463.19 EQB61153.1 - 0.17 11.3 6.6 5.4 6.4 6.6 2.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EQB61153.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb2_1 PF04563.15 EQB61154.1 - 6.3e-52 176.1 0.0 1.1e-51 175.2 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EQB61154.1 - 2.8e-17 63.0 2.8 6e-17 61.9 2.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 zf-ZPR1 PF03367.13 EQB61155.1 - 8.2e-17 61.5 3.7 1.1e-16 61.1 3.7 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain TBP PF00352.21 EQB61156.1 - 1.5e-28 98.5 0.5 6.7e-14 51.6 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EQB61156.1 - 0.076 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) TBP PF00352.21 EQB61157.1 - 7.5e-66 218.1 1.0 4.5e-32 109.8 0.3 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EQB61157.1 - 2.2e-06 27.7 0.1 0.01 15.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EQB61157.1 - 0.11 12.3 0.1 0.63 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) zf-RING_UBOX PF13445.6 EQB61158.1 - 0.0087 16.1 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EQB61158.1 - 0.039 14.1 0.6 0.12 12.5 0.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING tRNA_NucTran2_2 PF13735.6 EQB61158.1 - 0.041 13.9 2.9 4.3 7.3 0.2 2.3 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Ribo_biogen_C PF04034.13 EQB61158.1 - 0.044 13.5 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal RRT14 PF17075.5 EQB61158.1 - 3.5 7.7 15.5 0.15 12.2 7.3 2.0 1 1 1 2 2 2 0 Regular of rDNA transcription protein 14 Sacchrp_dh_NADP PF03435.18 EQB61160.1 - 2.8e-05 24.4 0.1 5.2e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NTNH_C PF08470.10 EQB61160.1 - 0.017 15.0 1.1 0.037 13.9 0.3 1.8 1 1 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Lipin_N PF04571.14 EQB61161.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 lipin, N-terminal conserved region RNA_pol_Rpb1_2 PF00623.20 EQB61162.1 - 4e-62 209.3 0.1 6.6e-62 208.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EQB61162.1 - 4.7e-37 128.0 2.2 1.2e-36 126.7 2.2 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EQB61162.1 - 1.3e-27 96.7 0.0 4.1e-27 95.0 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 EQB61162.1 - 2.6e-27 95.9 0.1 6e-27 94.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 EQB61162.1 - 3.3e-18 65.6 0.0 9.9e-18 64.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_2 PF00623.20 EQB61163.1 - 2.4e-62 210.1 0.1 3.8e-62 209.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EQB61163.1 - 6.6e-28 97.6 0.0 2.4e-27 95.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 EQB61163.1 - 2e-27 96.3 0.0 3.8e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 EQB61163.1 - 2.6e-18 65.9 0.0 6.1e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 EQB61164.1 - 4.5e-15 55.8 1.2 4.8e-15 55.7 1.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Astro_capsid_p PF12226.8 EQB61164.1 - 0.08 12.1 4.6 0.08 12.1 4.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HORMA PF02301.18 EQB61164.1 - 0.25 10.9 4.9 0.28 10.7 4.9 1.1 1 0 0 1 1 1 0 HORMA domain YqfQ PF14181.6 EQB61164.1 - 1 9.5 5.9 1.1 9.4 5.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein RNA_pol_Rpb1_5 PF04998.17 EQB61165.1 - 7e-21 74.8 0.0 8.5e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 SET PF00856.28 EQB61167.1 - 1.7e-15 57.8 2.0 1.7e-15 57.8 2.0 2.7 2 2 0 2 2 2 1 SET domain G_glu_transpept PF01019.21 EQB61168.1 - 3.7e-44 151.4 0.0 4.5e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.18 EQB61168.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Asparaginase G_glu_transpept PF01019.21 EQB61169.1 - 1.1e-51 176.2 0.0 1.2e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CLAG PF03805.13 EQB61169.1 - 0.033 11.8 2.2 0.044 11.4 2.2 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Spt5-NGN PF03439.13 EQB61169.1 - 0.057 13.3 0.3 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section S10_plectin PF03501.15 EQB61170.1 - 2.3e-13 50.0 0.2 2.9e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain SGT1 PF07093.11 EQB61170.1 - 0.016 13.6 0.1 0.018 13.5 0.1 1.0 1 0 0 1 1 1 0 SGT1 protein Ribosomal_L32e PF01655.18 EQB61171.1 - 1.4e-24 86.6 0.0 1.6e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Fzo_mitofusin PF04799.13 EQB61172.1 - 0.044 13.3 1.8 1.1 8.8 0.0 2.4 2 1 0 2 2 2 0 fzo-like conserved region Apt1 PF10351.9 EQB61172.1 - 0.089 11.6 6.3 0.85 8.4 0.5 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF2935 PF11155.8 EQB61172.1 - 2.9 8.2 7.3 12 6.2 2.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Pkinase PF00069.25 EQB61173.1 - 6.1e-13 48.7 0.2 6.1e-12 45.5 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61173.1 - 3.8e-05 23.1 0.0 0.00022 20.6 0.0 1.8 1 1 0 2 2 2 1 Protein tyrosine kinase PseudoU_synth_1 PF01416.20 EQB61175.1 - 4.9e-09 36.6 0.0 1.7e-08 34.9 0.0 1.9 2 1 0 2 2 2 1 tRNA pseudouridine synthase Ribosomal_S19e PF01090.19 EQB61176.1 - 7.8e-28 96.9 0.0 8.4e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e 2-ph_phosp PF04029.14 EQB61176.1 - 0.048 12.8 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase HTH_DeoR PF08220.12 EQB61176.1 - 0.16 11.8 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Pho88 PF10032.9 EQB61177.1 - 1e-31 109.6 2.4 1.2e-31 109.4 2.4 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) FPN1 PF06963.12 EQB61177.1 - 0.066 11.8 0.7 0.085 11.4 0.7 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) TGT PF01702.18 EQB61178.1 - 0.0047 16.1 5.8 0.05 12.8 3.4 2.1 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase RRM_1 PF00076.22 EQB61179.1 - 0.0026 17.5 0.3 0.0089 15.8 0.1 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EQB61179.1 - 0.0065 17.2 1.3 0.01 16.5 0.8 1.5 1 1 0 1 1 1 1 Torus domain RNA_bind PF08675.11 EQB61179.1 - 0.058 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain zf-CCCH_2 PF14608.6 EQB61179.1 - 0.26 11.8 1.9 0.51 10.9 0.8 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Proteasome PF00227.26 EQB61180.1 - 6.7e-24 84.4 0.0 7.9e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EQB61180.1 - 0.00019 21.1 0.0 0.00062 19.4 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5613 PF18467.1 EQB61181.1 - 0.02 15.3 0.1 0.037 14.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5613) Pkinase PF00069.25 EQB61182.1 - 2e-55 188.0 0.6 2e-55 188.0 0.6 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61182.1 - 6.8e-26 91.1 0.1 1.2e-25 90.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB61182.1 - 1.6e-10 40.8 0.0 2.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EQB61182.1 - 5.5e-05 22.3 0.5 5.5e-05 22.3 0.5 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EQB61182.1 - 7.1e-05 21.8 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EQB61182.1 - 9.9e-05 22.4 0.0 0.028 14.4 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EQB61182.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EQB61182.1 - 0.032 13.8 2.2 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 TFIID-31kDa PF02291.15 EQB61183.1 - 2.3e-35 121.3 0.0 2.6e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 EQB61183.1 - 3e-08 33.9 0.0 4.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EQB61183.1 - 4.9e-07 29.7 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 EQB61183.1 - 3.8e-05 24.0 0.0 5.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EQB61183.1 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 EQB61183.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold SMC_N PF02463.19 EQB61185.1 - 4e-24 85.3 0.1 4.5e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EQB61185.1 - 5e-05 23.3 0.0 6.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system KNOX2 PF03791.13 EQB61185.1 - 0.093 12.3 0.1 0.28 10.7 0.1 1.8 1 0 0 1 1 1 0 KNOX2 domain SMC_hinge PF06470.13 EQB61186.1 - 3e-17 63.0 0.0 8.8e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Bcr-Abl_Oligo PF09036.10 EQB61186.1 - 3.1 7.9 14.5 7.7 6.6 0.4 4.5 2 1 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain BLOC1S3 PF15753.5 EQB61186.1 - 4.5 7.4 12.6 1.3 9.1 1.6 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 SMC_N PF02463.19 EQB61187.1 - 7e-22 77.9 14.3 2.9e-21 75.9 14.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EQB61187.1 - 3e-13 50.2 37.2 3.9e-13 49.8 37.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EQB61187.1 - 3.4e-13 50.6 29.2 7.9e-13 49.4 29.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EQB61187.1 - 6.8e-08 32.1 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EQB61187.1 - 3.8e-07 30.2 0.1 3.8e-07 30.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EQB61187.1 - 0.0079 15.8 0.2 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF1977 PF09320.11 EQB61187.1 - 0.038 14.3 3.2 1.1 9.6 2.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) NACHT PF05729.12 EQB61187.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EQB61187.1 - 5.9 7.4 14.1 64 4.0 14.1 2.4 1 1 0 1 1 1 0 ABC transporter Gar1 PF04410.14 EQB61188.1 - 2.4e-17 63.2 6.0 3.9e-17 62.5 6.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region GHMP_kinases_C PF08544.13 EQB61189.1 - 0.021 15.2 0.0 0.029 14.7 0.0 1.2 1 0 0 1 1 1 0 GHMP kinases C terminal DIM PF08194.12 EQB61190.1 - 0.098 12.9 0.3 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 DIM protein TPR_19 PF14559.6 EQB61193.1 - 9.8e-07 29.2 0.0 0.0022 18.5 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EQB61193.1 - 0.23 12.4 0.0 49 5.1 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat DNA_primase_lrg PF04104.14 EQB61194.1 - 1.8e-41 142.3 7.4 3.1e-41 141.6 7.4 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pneumo_NS1 PF03438.13 EQB61194.1 - 0.0026 17.9 0.7 0.0065 16.6 0.7 1.8 1 1 0 1 1 1 1 Pneumovirus NS1 protein Ribonuclease_3 PF00636.26 EQB61195.1 - 6.8e-22 78.1 2.4 8.4e-15 55.3 0.1 2.6 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EQB61195.1 - 2.6e-15 56.7 0.0 2.1e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EQB61196.1 - 8.8e-08 32.2 0.0 1.8e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Fip1 PF05182.13 EQB61197.1 - 2.1e-21 75.1 3.3 3.1e-21 74.6 3.3 1.3 1 0 0 1 1 1 1 Fip1 motif DNA_mis_repair PF01119.19 EQB61198.1 - 1.7e-19 69.6 3.2 4.7e-19 68.2 3.2 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EQB61198.1 - 7.5e-17 61.4 0.1 1.9e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mlh1_C PF16413.5 EQB61198.1 - 1.3e-12 47.7 17.1 2.1e-05 24.0 1.6 3.8 3 1 1 4 4 4 3 DNA mismatch repair protein Mlh1 C-terminus HATPase_c PF02518.26 EQB61198.1 - 1.5e-08 35.1 0.5 5.6e-08 33.3 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RTTN_N PF14726.6 EQB61198.1 - 0.022 15.5 0.4 0.13 13.1 0.4 2.4 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning DUF3531 PF12049.8 EQB61198.1 - 0.06 13.3 0.1 0.06 13.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3531) HEAT PF02985.22 EQB61201.1 - 2.1e-06 27.5 0.6 1.3 9.4 0.1 4.3 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EQB61201.1 - 7.5e-05 23.0 0.0 1.4 9.3 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats DUF3879 PF12995.7 EQB61201.1 - 0.0083 15.9 0.4 0.016 15.0 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3879) RTP1_C1 PF10363.9 EQB61201.1 - 0.011 15.9 4.1 0.012 15.8 0.7 2.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MitMem_reg PF13012.6 EQB61201.1 - 0.11 12.9 2.9 0.3 11.5 2.6 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Cnd1 PF12717.7 EQB61201.1 - 0.2 11.7 11.0 2.2 8.3 0.8 3.0 1 1 2 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HiaBD2 PF15403.6 EQB61201.1 - 0.93 9.9 3.4 2.3 8.7 3.4 1.7 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF1091 PF06477.13 EQB61201.1 - 5.1 7.6 8.1 9.1 6.8 0.6 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1091) Ribosomal_S17e PF00833.18 EQB61202.1 - 7e-31 106.7 4.4 8.1e-31 106.5 4.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Peptidase_S24 PF00717.23 EQB61203.1 - 5.4e-08 32.7 0.0 8.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Ribosomal_L7Ae PF01248.26 EQB61206.1 - 2.5e-20 72.0 1.2 3e-20 71.7 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PAP_central PF04928.17 EQB61207.1 - 3.1e-86 288.4 0.0 4.9e-86 287.8 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EQB61207.1 - 2e-20 73.1 1.5 2.1e-13 50.3 0.1 2.5 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EQB61207.1 - 7e-14 51.9 0.1 1.8e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EQB61207.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EQB61207.1 - 0.0092 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain DUF4269 PF14091.6 EQB61207.1 - 0.019 15.2 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Histone PF00125.24 EQB61208.1 - 4e-06 27.2 0.0 5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EQB61208.1 - 7.8e-05 22.9 1.4 0.00012 22.3 1.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 EQB61208.1 - 0.0021 18.1 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region WD40 PF00400.32 EQB61209.1 - 4.3e-11 43.2 5.7 0.00016 22.4 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB61209.1 - 2.5e-08 34.1 0.0 0.0019 18.5 0.2 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DNA_photolyase PF00875.18 EQB61210.1 - 1e-05 25.6 0.0 2.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 DNA photolyase ACAS_N PF16177.5 EQB61210.1 - 0.093 12.7 2.6 1.5 8.8 0.1 3.4 2 1 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus AAA PF00004.29 EQB61212.1 - 3.5e-11 43.6 0.0 7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EQB61212.1 - 1.3e-09 38.0 0.2 1.1e-07 31.8 0.2 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit Sigma54_activ_2 PF14532.6 EQB61212.1 - 4.2e-07 30.2 0.0 8.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 EQB61212.1 - 4.6e-07 29.7 0.2 1.2e-06 28.4 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EQB61212.1 - 5.2e-07 29.7 0.0 5.2e-07 29.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EQB61212.1 - 5.6e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EQB61212.1 - 6.2e-06 26.5 0.2 0.0098 16.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 EQB61212.1 - 9.2e-06 26.2 0.2 2.1e-05 25.1 0.0 1.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EQB61212.1 - 2.6e-05 24.6 0.2 0.00013 22.3 0.0 2.2 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 EQB61212.1 - 4.1e-05 24.0 0.1 0.002 18.5 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EQB61212.1 - 8.7e-05 22.5 0.9 0.0078 16.2 0.8 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EQB61212.1 - 0.00013 21.8 0.0 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EQB61212.1 - 0.0002 20.8 0.2 0.019 14.3 0.0 2.8 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI Rep_fac_C PF08542.11 EQB61212.1 - 0.00034 21.0 0.1 0.0011 19.3 0.1 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_19 PF13245.6 EQB61212.1 - 0.00044 20.6 0.3 0.22 11.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EQB61212.1 - 0.00076 19.7 0.0 0.0013 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EQB61212.1 - 0.00088 19.0 0.0 0.33 10.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EQB61212.1 - 0.001 19.3 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EQB61212.1 - 0.0031 17.4 2.6 0.0059 16.5 0.3 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain ATPase_2 PF01637.18 EQB61212.1 - 0.0073 16.2 1.7 0.013 15.5 0.5 2.0 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea PhoH PF02562.16 EQB61212.1 - 0.0082 15.6 0.1 3.6 7.0 0.0 2.3 1 1 1 2 2 2 2 PhoH-like protein AAA_assoc_2 PF16193.5 EQB61212.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain ATPase PF06745.13 EQB61212.1 - 0.013 14.8 3.1 0.86 8.9 0.0 3.0 2 1 1 3 3 3 0 KaiC TniB PF05621.11 EQB61212.1 - 0.015 14.7 0.0 0.06 12.8 0.0 1.8 1 1 1 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 EQB61212.1 - 0.018 14.8 0.5 0.049 13.4 0.1 1.7 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 EQB61212.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Roc PF08477.13 EQB61212.1 - 0.031 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EQB61212.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EQB61212.1 - 0.079 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EQB61212.1 - 0.08 13.4 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EQB61212.1 - 0.09 12.5 0.0 0.33 10.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EQB61212.1 - 0.12 12.3 0.5 0.92 9.4 0.0 2.4 1 1 1 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.18 EQB61212.1 - 0.12 11.7 0.1 2.1 7.6 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family DUF1829 PF08862.10 EQB61212.1 - 0.96 10.0 5.7 1 9.9 2.4 2.6 2 1 1 3 3 2 0 Domain of unknown function DUF1829 DnaJ PF00226.31 EQB61213.1 - 6.5e-05 23.0 0.7 6.5e-05 23.0 0.7 2.1 2 0 0 2 2 2 1 DnaJ domain HSCB_C PF07743.13 EQB61213.1 - 0.0037 17.7 9.3 0.024 15.1 6.6 2.8 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain NAD_binding_5 PF07994.12 EQB61213.1 - 0.41 10.0 2.4 0.42 9.9 2.1 1.3 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase Cbl_N PF02262.16 EQB61216.1 - 3.9 7.5 9.4 1.3 9.1 5.9 2.0 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Muskelin_N PF06588.11 EQB61217.1 - 2e-16 60.5 0.1 1.6e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 Muskelin N-terminus YabA PF06156.13 EQB61220.1 - 0.0057 17.3 2.0 0.0075 16.9 1.1 1.7 2 0 0 2 2 2 1 Initiation control protein YabA HALZ PF02183.18 EQB61220.1 - 0.011 15.9 5.3 0.012 15.8 2.9 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIVA PF05103.13 EQB61220.1 - 0.015 15.4 1.2 0.015 15.4 1.2 1.7 2 0 0 2 2 2 0 DivIVA protein NRBF2 PF08961.10 EQB61220.1 - 0.021 14.4 0.5 0.034 13.8 0.5 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator CBM_X2 PF03442.14 EQB61220.1 - 0.19 11.9 1.8 14 5.9 0.0 2.4 1 1 1 2 2 2 0 Carbohydrate binding domain X2 Yippee-Mis18 PF03226.14 EQB61221.1 - 2.1e-14 53.6 1.0 4.2e-14 52.6 1.0 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Gti1_Pac2 PF09729.9 EQB61221.1 - 0.82 9.7 5.9 1.1 9.3 5.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Yippee-Mis18 PF03226.14 EQB61222.1 - 6.8e-09 35.9 0.3 1.4e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Methyltr_RsmB-F PF01189.17 EQB61223.1 - 8.6e-33 113.7 0.8 4.9e-24 85.1 0.1 3.5 3 1 0 3 3 3 3 16S rRNA methyltransferase RsmB/F DUF2621 PF11084.8 EQB61223.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2621) Bactofilin PF04519.13 EQB61223.1 - 0.045 14.1 0.5 0.045 14.1 0.5 2.1 2 0 0 2 2 2 0 Polymer-forming cytoskeletal zf_C2H2_6 PF18450.1 EQB61224.1 - 0.029 14.1 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Zinc Finger domain GIIM PF08388.11 EQB61225.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Group II intron, maturase-specific domain DUF2207 PF09972.9 EQB61227.1 - 0.0034 16.2 3.4 0.0043 15.9 3.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) HTH_50 PF18024.1 EQB61230.1 - 0.11 12.1 0.6 2.5 7.8 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain NAD_binding_9 PF13454.6 EQB61231.1 - 0.71 9.8 3.9 1.1 9.2 2.4 1.9 1 1 1 2 2 2 0 FAD-NAD(P)-binding DUF2207 PF09972.9 EQB61232.1 - 0.00021 20.2 1.4 0.00022 20.1 1.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Presenilin PF01080.17 EQB61234.1 - 1.7 7.3 6.1 3.1 6.5 6.1 1.4 1 0 0 1 1 1 0 Presenilin IlvGEDA_leader PF08046.11 EQB61239.1 - 0.18 11.3 5.8 0.31 10.5 5.8 1.4 1 0 0 1 1 1 0 IlvGEDA operon leader peptide CelTOS PF18659.1 EQB61239.1 - 0.21 12.1 4.4 0.26 11.7 0.4 2.1 1 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Eno-Rase_FAD_bd PF07055.12 EQB61241.1 - 0.017 15.5 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DUF1128 PF06569.11 EQB61241.1 - 0.043 13.8 0.2 0.079 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) NYD-SP28_assoc PF14775.6 EQB61245.1 - 0.0041 17.2 0.7 0.014 15.5 0.7 2.1 1 0 0 1 1 1 1 Sperm tail C-terminal domain DUF740 PF05340.12 EQB61245.1 - 1.9 7.1 12.8 2.9 6.5 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) KIAA1430 PF13879.6 EQB61246.1 - 0.0083 16.9 2.6 0.0083 16.9 2.6 3.3 3 1 0 3 3 3 1 KIAA1430 homologue SWIRM-assoc_3 PF16498.5 EQB61246.1 - 0.083 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal APOBEC_C PF05240.14 EQB61247.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.0 1 1 1 2 2 2 0 APOBEC-like C-terminal domain DdrB PF12747.7 EQB61249.1 - 0.078 12.8 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 DdrB-like protein Ntox16 PF15523.6 EQB61249.1 - 2.7 8.3 9.4 0.34 11.2 2.8 2.7 2 1 1 3 3 3 0 Novel toxin 16 KASH_CCD PF14662.6 EQB61250.1 - 0.0091 15.8 2.6 0.0091 15.8 2.6 2.0 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH Ins_allergen_rp PF06757.13 EQB61250.1 - 0.011 15.7 3.6 0.088 12.8 0.4 2.9 1 1 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification LAGLIDADG_WhiA PF14527.6 EQB61250.1 - 0.21 11.7 4.0 0.14 12.2 0.8 2.2 1 1 0 2 2 2 0 WhiA LAGLIDADG-like domain DEAD PF00270.29 EQB61251.1 - 2.6e-39 134.8 0.2 4.1e-39 134.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EQB61251.1 - 9.7e-22 77.4 0.2 8.9e-20 71.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EQB61251.1 - 9.8e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA_3 PF09288.10 EQB61251.1 - 0.00032 20.4 0.4 1.2 9.0 0.0 3.3 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain AAA_30 PF13604.6 EQB61251.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EQB61251.1 - 0.081 13.2 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EQB61251.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 1 0 1 1 1 0 Helicase Cation_ATPase PF13246.6 EQB61252.1 - 6e-09 35.9 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EQB61252.1 - 0.0045 16.5 0.9 0.008 15.7 0.9 1.3 1 0 0 1 1 1 1 E1-E2 ATPase CM_1 PF07736.11 EQB61252.1 - 0.022 15.1 0.1 0.071 13.5 0.1 1.9 1 0 0 1 1 1 0 Chorismate mutase type I SLATT_fungal PF18142.1 EQB61252.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain PhoLip_ATPase_C PF16212.5 EQB61253.1 - 3.5e-26 92.5 10.9 5.3e-26 91.9 10.9 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EQB61253.1 - 7.2e-08 33.0 0.0 2.2e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EQB61253.1 - 0.00048 19.9 0.4 0.015 15.1 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF624 PF04854.14 EQB61253.1 - 2.9 8.1 8.7 1.3 9.2 3.1 3.0 3 1 0 3 3 3 0 Protein of unknown function, DUF624 PYC_OADA PF02436.18 EQB61255.1 - 0.52 10.0 2.5 2.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Conserved carboxylase domain UPF0515 PF15135.6 EQB61255.1 - 9.3 5.5 7.9 2.2 7.6 3.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 CtnDOT_TraJ PF07863.11 EQB61256.1 - 0.081 13.6 0.2 0.12 13.1 0.2 1.2 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon FAD_binding_1 PF00667.20 EQB61257.1 - 1.4e-10 41.2 0.0 3.1e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EQB61257.1 - 1.6e-09 38.4 0.0 4.6e-08 33.7 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EQB61257.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.9 2 1 0 3 3 3 0 Ferric reductase NAD binding domain SNase PF00565.17 EQB61258.1 - 6.8e-25 87.6 0.0 9.1e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue VID27 PF08553.10 EQB61259.1 - 4.1e-82 276.1 2.5 5.5e-82 275.7 2.5 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain UCH PF00443.29 EQB61260.1 - 0.11 11.9 0.3 0.29 10.6 0.3 1.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Lipase_3 PF01764.25 EQB61261.1 - 2.5e-17 63.1 0.0 6.2e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) RNA_pol_Rpb2_5 PF04567.17 EQB61261.1 - 0.13 12.8 1.0 0.47 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 Abhydrolase_1 PF00561.20 EQB61261.1 - 0.15 11.6 2.1 0.27 10.9 0.2 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold UPF0449 PF15136.6 EQB61261.1 - 0.26 11.8 1.7 0.35 11.4 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 LRR_8 PF13855.6 EQB61262.1 - 7.5e-12 44.8 39.4 2.3e-08 33.7 11.4 5.1 3 3 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EQB61262.1 - 3.3e-07 30.5 50.6 4e-05 23.9 12.5 8.0 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) RPN1_RPN2_N PF17781.1 EQB61263.1 - 2.4e-11 43.6 0.1 2.8e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain DUF2482 PF10655.9 EQB61263.1 - 0.04 14.4 0.5 0.04 14.4 0.5 1.7 2 1 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) PC_rep PF01851.22 EQB61264.1 - 0.00025 21.3 1.3 1.1 9.9 0.0 4.5 4 0 0 4 4 4 2 Proteasome/cyclosome repeat RPN1_RPN2_N PF17781.1 EQB61264.1 - 0.012 15.0 0.4 0.024 14.0 0.4 1.4 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain B56 PF01603.20 EQB61265.1 - 8.4e-21 74.4 38.7 3.7e-11 42.6 17.9 2.4 2 1 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) LRAT PF04970.13 EQB61266.1 - 0.14 12.4 5.7 0.1 12.9 2.7 2.1 1 1 1 2 2 2 0 Lecithin retinol acyltransferase Pkinase PF00069.25 EQB61267.1 - 1.5e-55 188.5 1.2 1.5e-54 185.1 0.9 2.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61267.1 - 6.8e-26 91.1 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EQB61267.1 - 1.1e-05 24.6 0.5 1.7e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EQB61267.1 - 6e-05 22.5 0.1 0.0001 21.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EQB61267.1 - 0.00059 19.8 0.5 0.013 15.5 0.5 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EQB61267.1 - 0.0021 17.7 0.3 0.0054 16.3 0.3 1.7 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EQB61267.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UCH PF00443.29 EQB61268.1 - 4.1e-05 23.2 7.1 0.0071 15.9 7.1 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_8 PF13833.6 EQB61270.1 - 0.00033 20.4 0.3 0.00081 19.2 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EQB61270.1 - 0.00045 19.9 0.3 0.0028 17.4 0.3 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EQB61270.1 - 0.0022 18.4 0.1 0.0044 17.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EQB61270.1 - 0.0065 15.9 1.4 0.019 14.5 1.4 1.8 1 0 0 1 1 1 1 EF hand VanZ PF04892.12 EQB61270.1 - 1 10.0 6.7 1.8 9.3 6.7 1.6 1 1 0 1 1 1 0 VanZ like family Peptidase_M48 PF01435.18 EQB61271.1 - 9.1e-38 130.0 0.0 1.1e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 EQB61271.1 - 0.00017 21.4 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 SprT-like family DUF2268 PF10026.9 EQB61271.1 - 0.0015 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Peptidase_M56 PF05569.11 EQB61271.1 - 0.0058 15.9 0.9 0.0099 15.1 0.2 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 Peptidase_M48_N PF16491.5 EQB61271.1 - 0.087 12.7 0.7 0.087 12.7 0.7 2.3 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices Ribosomal_L7Ae PF01248.26 EQB61272.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Spc24 PF08286.11 EQB61273.1 - 3.5e-05 24.0 3.5 3.5e-05 24.0 3.5 2.0 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 EQB61273.1 - 0.11 12.7 8.4 1 9.5 7.8 2.2 1 1 0 1 1 1 0 Tropomyosin like FlxA PF14282.6 EQB61273.1 - 0.41 10.6 6.3 2.6 8.1 0.5 2.3 1 1 1 2 2 2 0 FlxA-like protein FapA PF03961.13 EQB61273.1 - 0.43 9.1 12.0 0.49 8.9 12.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TcA_RBD PF18518.1 EQB61273.1 - 3.7 7.8 9.3 0.73 10.1 3.0 2.0 1 1 1 2 2 2 0 TcA receptor binding domain Ribosomal_S8 PF00410.19 EQB61273.1 - 5 7.1 11.0 3 7.8 7.1 2.0 1 1 1 2 2 2 0 Ribosomal protein S8 Plk4_PB1 PF18190.1 EQB61274.1 - 3e-05 24.2 4.8 0.032 14.4 0.8 2.8 1 1 0 2 2 2 2 Polo-like Kinase 4 Polo Box 1 Ery_res_leader2 PF08057.11 EQB61274.1 - 0.35 11.4 2.7 33 5.5 0.2 2.6 2 0 0 2 2 2 0 Erythromycin resistance leader peptide PRA1 PF03208.19 EQB61275.1 - 1.4e-14 53.9 1.3 1.9e-14 53.5 1.3 1.1 1 0 0 1 1 1 1 PRA1 family protein zf-Sec23_Sec24 PF04810.15 EQB61277.1 - 1.8e-06 27.9 2.1 1.8e-06 27.9 2.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EQB61277.1 - 0.0037 16.6 0.1 0.011 15.2 0.1 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Fe_dep_repr_C PF02742.15 EQB61277.1 - 0.097 12.8 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain zf-RanBP PF00641.18 EQB61277.1 - 0.11 11.8 0.5 0.11 11.8 0.5 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Helicase_C PF00271.31 EQB61280.1 - 8.1e-22 77.7 0.6 1.1e-19 70.8 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EQB61280.1 - 9.6e-13 48.7 3.9 9.6e-13 48.7 3.9 2.2 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 EQB61280.1 - 1.4e-07 31.5 0.1 5.2e-07 29.6 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase YfcL PF08891.11 EQB61280.1 - 0.047 14.0 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 YfcL protein RNA_replicase_B PF03431.13 EQB61281.1 - 0.34 9.3 3.6 0.38 9.2 3.6 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain S-AdoMet_synt_C PF02773.16 EQB61283.1 - 2.2e-64 215.6 0.0 4.3e-64 214.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EQB61283.1 - 8.2e-44 148.7 0.0 1.6e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EQB61283.1 - 1.5e-38 131.5 0.3 3.1e-38 130.4 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Sugar_tr PF00083.24 EQB61284.1 - 2.2e-36 125.7 21.8 1.2e-24 87.1 5.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EQB61284.1 - 4.5e-08 32.4 24.1 7.3e-06 25.1 24.1 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily SPW PF03779.14 EQB61284.1 - 0.019 14.6 0.4 0.019 14.6 0.4 2.7 4 0 0 4 4 4 0 SPW repeat TMEM107 PF14995.6 EQB61284.1 - 1.1 9.8 9.5 0.06 13.8 2.3 2.6 2 1 0 2 2 2 0 Transmembrane protein RVT_1 PF00078.27 EQB61288.1 - 0.0085 15.6 0.2 0.016 14.7 0.2 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GerPE PF10970.8 EQB61289.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Spore germination protein GerPE FKBP_N PF01346.18 EQB61289.1 - 1.3 10.1 3.9 1.7 9.7 0.0 2.8 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DEAD PF00270.29 EQB61291.1 - 2.4e-28 99.1 0.2 2.4e-28 99.1 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EQB61291.1 - 1.4e-25 89.8 1.9 4e-25 88.3 0.2 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EQB61291.1 - 2.3e-05 24.5 0.1 2.3e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EQB61291.1 - 0.0016 17.7 0.8 0.32 10.2 0.2 2.3 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase RNA_pol_Rpb6 PF01192.22 EQB61293.1 - 9.5e-12 44.7 0.1 1.2e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 Adap_comp_sub PF00928.21 EQB61294.1 - 0.0034 16.8 9.6 0.006 16.0 9.6 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ribosomal_S19 PF00203.21 EQB61295.1 - 2.6e-22 78.5 0.0 3.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Tam41_Mmp37 PF09139.11 EQB61295.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial ANAPC4_WD40 PF12894.7 EQB61297.1 - 2.3e-06 27.8 1.5 0.15 12.4 0.5 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NdhO PF11910.8 EQB61297.1 - 0.099 12.8 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Cyanobacterial and plant NDH-1 subunit O Mod_r PF07200.13 EQB61298.1 - 0.85 9.7 5.5 0.19 11.9 1.4 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FadA PF09403.10 EQB61298.1 - 6.2 7.4 9.3 0.096 13.2 1.5 2.0 3 0 0 3 3 3 0 Adhesion protein FadA Adap_comp_sub PF00928.21 EQB61299.1 - 0.0034 16.8 9.6 0.006 16.0 9.6 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RNA_pol_Rpb6 PF01192.22 EQB61300.1 - 9.5e-12 44.7 0.1 1.2e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb6 PET117 PF15786.5 EQB61301.1 - 0.091 13.0 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Ribosomal_L26 PF16906.5 EQB61303.1 - 3.6e-25 88.2 0.1 4.9e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EQB61303.1 - 9.4e-07 28.6 1.0 1.7e-06 27.7 1.0 1.5 1 0 0 1 1 1 1 KOW motif DUF2423 PF10338.9 EQB61303.1 - 0.038 14.2 1.2 0.038 14.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) RRM_1 PF00076.22 EQB61304.1 - 1.1e-17 63.6 1.2 1.4e-17 63.2 0.2 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 EQB61304.1 - 1.3e-14 54.4 1.8 1.3e-14 54.4 1.8 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 PI_PP_I PF18363.1 EQB61304.1 - 0.22 11.7 4.0 0.42 10.8 0.8 2.2 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain Thioredoxin PF00085.20 EQB61305.1 - 1.4e-19 70.0 1.1 1.9e-14 53.5 0.2 3.4 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_2 PF13098.6 EQB61305.1 - 0.0001 22.7 0.3 0.0048 17.3 0.1 3.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EQB61305.1 - 0.00099 19.1 14.9 0.0015 18.5 1.7 3.6 1 1 2 3 3 3 2 Thioredoxin-like domain Sulfate_transp PF00916.20 EQB61306.1 - 6.8e-15 54.7 18.5 1.6e-13 50.2 17.9 2.2 1 1 0 1 1 1 1 Sulfate permease family Sulfate_transp PF00916.20 EQB61307.1 - 3.3e-17 62.3 22.3 1.7e-15 56.7 20.8 2.3 1 1 0 1 1 1 1 Sulfate permease family Smr PF01713.21 EQB61308.1 - 4.9e-05 23.6 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 EQB61308.1 - 0.00081 19.0 0.2 0.0019 17.8 0.2 1.6 1 0 0 1 1 1 1 CUE domain Histone PF00125.24 EQB61309.1 - 0.00015 22.1 0.3 0.00021 21.6 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EQB61309.1 - 0.0027 18.0 0.1 0.0052 17.1 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein SecD_SecF PF02355.16 EQB61309.1 - 0.033 13.6 0.1 0.064 12.6 0.1 1.4 1 1 0 1 1 1 0 Protein export membrane protein HMG_box PF00505.19 EQB61310.1 - 1.6e-14 54.1 17.8 1.3e-08 35.1 4.5 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EQB61310.1 - 7e-07 29.8 16.8 0.0013 19.3 2.4 2.5 2 0 0 2 2 2 2 HMG-box domain TPT PF03151.16 EQB61312.1 - 3.3e-06 26.7 2.6 3.6e-06 26.5 2.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family AGTRAP PF06396.11 EQB61312.1 - 0.093 12.5 3.1 4.6 7.0 0.8 2.2 1 1 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) EamA PF00892.20 EQB61312.1 - 0.095 12.9 6.6 0.12 12.6 6.6 1.4 1 1 0 1 1 1 0 EamA-like transporter family Phage_holin_2_4 PF16082.5 EQB61312.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like ATP_bind_1 PF03029.17 EQB61313.1 - 7.1e-31 107.8 0.6 7.9e-31 107.7 0.6 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EQB61313.1 - 4.3e-05 23.7 0.0 5.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EQB61313.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EQB61313.1 - 0.0033 17.4 1.8 0.0046 16.9 1.3 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EQB61313.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EQB61313.1 - 0.019 15.0 0.3 0.1 12.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EQB61313.1 - 0.023 15.1 1.7 0.89 10.0 1.7 2.3 1 1 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 EQB61313.1 - 0.026 14.6 0.2 0.45 10.6 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EQB61313.1 - 0.035 14.7 0.1 0.07 13.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EQB61313.1 - 0.065 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.6 EQB61313.1 - 0.13 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EQB61313.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin Diphthamide_syn PF01866.17 EQB61314.1 - 9e-08 31.9 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DSPn PF14671.6 EQB61315.1 - 0.03 14.8 1.9 0.036 14.5 1.9 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half OSCP PF00213.18 EQB61315.1 - 0.057 13.6 1.4 0.08 13.1 1.4 1.2 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Resolvase PF00239.21 EQB61315.1 - 0.071 13.2 0.1 0.12 12.4 0.0 1.4 2 0 0 2 2 2 0 Resolvase, N terminal domain KGK PF08872.10 EQB61315.1 - 0.51 10.8 6.2 6.2 7.3 0.3 2.2 1 1 1 2 2 2 0 KGK domain P53_C PF11619.8 EQB61316.1 - 0.22 11.6 1.6 2 8.6 1.6 2.2 1 1 0 1 1 1 0 Transcription factor P53 - C terminal domain Exo_endo_phos PF03372.23 EQB61317.1 - 3.8e-06 26.6 0.0 5.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EQB61317.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ANAPC4_WD40 PF12894.7 EQB61318.1 - 0.026 14.8 0.0 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ACPS PF01648.20 EQB61320.1 - 0.04 14.0 0.0 0.088 12.9 0.0 1.5 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Porin_3 PF01459.22 EQB61321.1 - 2.9e-20 72.9 1.1 3.8e-20 72.5 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin FAD_binding_1 PF00667.20 EQB61321.1 - 0.0032 17.1 0.6 0.061 12.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain RRXRR PF14239.6 EQB61322.1 - 0.068 13.0 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 RRXRR protein MDD_C PF18376.1 EQB61323.1 - 2.2e-35 122.1 0.1 4.1e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EQB61323.1 - 5.2e-08 33.0 0.1 9.3e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF4974 PF16344.5 EQB61323.1 - 0.021 14.8 2.9 8.1 6.5 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4974) UCH_N PF16674.5 EQB61323.1 - 0.12 12.3 1.7 3.3 7.7 0.3 2.7 2 0 0 2 2 2 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 P53_tetramer PF07710.11 EQB61324.1 - 0.0019 17.5 0.0 0.0071 15.7 0.0 2.1 2 0 0 2 2 2 1 P53 tetramerisation motif TAFII55_N PF04658.13 EQB61325.1 - 1.5e-22 80.0 4.0 1.5e-22 80.0 4.0 2.7 2 1 0 2 2 2 1 TAFII55 protein conserved region GCD14 PF08704.10 EQB61325.1 - 0.81 9.3 4.0 0.28 10.8 0.3 1.8 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit ATP-synt_E PF05680.12 EQB61325.1 - 4 7.8 11.4 5.7 7.4 4.7 2.4 1 1 1 2 2 2 0 ATP synthase E chain Bromo_TP_like PF17027.5 EQB61326.1 - 3.7e-28 98.1 7.9 3.7e-28 98.1 7.9 1.8 1 1 1 2 2 2 1 Histone-fold protein Bromo_TP PF07524.13 EQB61326.1 - 3.8e-05 23.6 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIIB PF00382.19 EQB61327.1 - 6.7e-26 90.1 0.0 5.2e-14 52.0 0.0 2.7 2 1 1 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EQB61327.1 - 6.5e-08 32.0 1.9 1.7e-07 30.7 1.9 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 EQB61327.1 - 0.00073 19.2 2.8 0.0019 17.9 2.8 1.7 1 0 0 1 1 1 1 Ribosomal protein S27 Cyclin_N PF00134.23 EQB61327.1 - 0.025 14.3 0.2 0.13 12.0 0.1 2.2 3 0 0 3 3 3 0 Cyclin, N-terminal domain HTH_40 PF14493.6 EQB61327.1 - 0.029 14.8 0.1 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain BRF1 PF07741.13 EQB61327.1 - 0.16 12.3 9.8 0.05 13.9 3.4 2.7 2 1 1 3 3 3 0 Brf1-like TBP-binding domain PhnA_Zn_Ribbon PF08274.12 EQB61327.1 - 3.5 7.7 5.0 2.1 8.4 1.4 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Synaptobrevin PF00957.21 EQB61328.1 - 6.7e-08 32.2 0.1 7.4e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Synaptobrevin SecE PF00584.20 EQB61328.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Myosin_tail_1 PF01576.19 EQB61328.1 - 0.017 13.0 0.8 0.017 13.0 0.8 1.0 1 0 0 1 1 1 0 Myosin tail DUF948 PF06103.11 EQB61328.1 - 0.19 12.0 1.2 0.88 9.9 0.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LRR_4 PF12799.7 EQB61329.1 - 7e-13 48.5 35.4 1.4e-05 25.3 3.8 4.9 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB61329.1 - 3.1e-11 42.9 23.2 1.2e-05 25.0 3.2 5.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 EQB61329.1 - 0.00016 21.4 15.0 0.69 10.1 0.1 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_9 PF14580.6 EQB61329.1 - 0.00065 19.3 17.5 0.0029 17.1 5.2 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EQB61329.1 - 0.038 14.5 20.9 29 5.7 0.1 6.6 5 1 0 5 5 5 0 Leucine Rich Repeat DUF2322 PF10084.9 EQB61329.1 - 0.11 12.6 1.2 9.4 6.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Organ_specific PF10950.8 EQB61330.1 - 0.011 16.4 0.2 0.029 15.1 0.2 1.7 1 0 0 1 1 1 0 Organ specific protein DUF4891 PF16232.5 EQB61331.1 - 0.099 13.2 0.3 0.25 11.9 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4891) dCMP_cyt_deam_1 PF00383.23 EQB61333.1 - 1.9e-15 56.6 0.2 2.6e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EQB61333.1 - 1.1e-12 48.3 0.1 1.7e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EQB61333.1 - 2.2e-05 24.2 0.6 0.084 12.5 0.3 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases GDA1_CD39 PF01150.17 EQB61336.1 - 1.1e-12 47.4 4.2 3.9e-12 45.6 2.2 2.0 1 1 1 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EQB61336.1 - 4.1e-05 23.2 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Hydantoinase_A PF01968.18 EQB61336.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase RRM_DME PF15628.6 EQB61336.1 - 0.022 14.9 1.1 1.6 9.0 0.1 2.2 2 0 0 2 2 2 0 RRM in Demeter FH2 PF02181.23 EQB61337.1 - 2.6e-06 26.8 2.7 6.1e-06 25.6 2.5 1.7 1 1 1 2 2 2 1 Formin Homology 2 Domain TctB PF07331.11 EQB61338.1 - 2.2 8.6 19.2 0.72 10.1 7.0 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Coatamer_beta_C PF07718.12 EQB61339.1 - 3.1e-16 59.5 0.4 7.6e-16 58.3 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Adaptin_N PF01602.20 EQB61339.1 - 6.7e-14 51.3 0.7 6.7e-14 51.3 0.7 2.9 3 0 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 EQB61339.1 - 0.016 15.4 0.0 0.3 11.5 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat Prenyltrans PF00432.21 EQB61341.1 - 5.3e-46 154.0 0.0 5.4e-10 38.8 0.0 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EQB61341.1 - 0.00017 20.8 0.0 0.33 10.0 0.0 3.7 2 2 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EQB61341.1 - 0.15 11.1 0.0 1.1 8.2 0.0 2.2 1 1 1 2 2 2 0 A-macroglobulin TED domain MMR_HSR1_Xtn PF16897.5 EQB61342.1 - 6.6e-36 122.5 3.4 1.3e-35 121.6 3.4 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EQB61342.1 - 2.4e-19 69.5 0.6 6.3e-19 68.1 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EQB61342.1 - 3.3e-11 42.9 0.0 6.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EQB61342.1 - 0.0014 18.0 0.2 0.0031 16.8 0.0 1.6 2 0 0 2 2 2 1 AIG1 family MeaB PF03308.16 EQB61342.1 - 0.0086 15.1 0.2 0.14 11.1 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EQB61342.1 - 0.013 15.7 0.1 0.1 12.8 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EQB61342.1 - 0.017 15.2 0.3 4.4 7.3 0.0 2.7 1 1 0 2 2 2 0 Dynamin family Arf PF00025.21 EQB61342.1 - 0.02 14.3 0.3 0.1 12.0 0.0 2.1 2 1 1 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.22 EQB61342.1 - 0.042 13.0 0.5 0.1 11.7 0.0 2.0 2 1 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 EQB61342.1 - 0.045 13.6 0.4 1.4 8.8 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EQB61342.1 - 0.046 13.2 1.5 0.17 11.3 0.3 2.4 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EQB61342.1 - 0.053 13.9 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 EQB61342.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EQB61342.1 - 0.14 12.4 0.1 0.67 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EQB61342.1 - 0.15 12.3 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EQB61343.1 - 3.4e-09 37.2 0.4 0.22 12.5 0.0 4.4 3 1 1 4 4 4 3 WD domain, G-beta repeat Adeno_PV PF03910.13 EQB61344.1 - 0.29 9.8 0.7 0.41 9.3 0.3 1.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV DUF3153 PF11353.8 EQB61346.1 - 0.044 13.3 3.7 0.077 12.6 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF447 PF04289.12 EQB61346.1 - 0.097 12.4 0.9 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF447) Peptidase_M15 PF01427.17 EQB61346.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase CAF1A PF12253.8 EQB61349.1 - 0.32 11.2 18.2 0.25 11.6 14.4 2.7 2 1 0 2 2 2 0 Chromatin assembly factor 1 subunit A zf-RVT PF13966.6 EQB61351.1 - 0.088 13.5 0.6 0.22 12.3 0.2 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase BsuBI_PstI_RE PF06616.11 EQB61351.1 - 0.094 12.0 1.0 0.36 10.1 0.5 2.1 1 1 1 2 2 2 0 BsuBI/PstI restriction endonuclease domain TraF PF13728.6 EQB61351.1 - 0.11 12.3 0.1 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 F plasmid transfer operon protein WD40_like PF17005.5 EQB61352.1 - 4.9e-11 42.5 70.0 7.5e-05 22.2 10.3 4.5 1 1 3 4 4 4 4 WD40-like domain BBS2_Mid PF14783.6 EQB61352.1 - 0.0081 16.2 3.2 2.2 8.3 0.2 3.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region XRN_N PF03159.18 EQB61356.1 - 7.2e-21 74.7 0.1 8.3e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EQB61357.1 - 8.5e-54 183.2 12.3 1.8e-40 139.2 6.3 2.0 1 1 1 2 2 2 2 Xrn1 helical domain ERp29_N PF07912.13 EQB61357.1 - 0.071 13.3 1.0 0.76 9.9 0.1 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain XRN_M PF17846.1 EQB61358.1 - 5.7e-41 140.9 5.1 6.6e-41 140.7 5.1 1.0 1 0 0 1 1 1 1 Xrn1 helical domain ERp29_N PF07912.13 EQB61358.1 - 0.034 14.3 1.0 0.51 10.5 0.1 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain Coilin_N PF15862.5 EQB61358.1 - 0.083 12.7 0.0 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus DNA_pol_E_B PF04042.16 EQB61359.1 - 6.6e-19 68.1 0.2 5.1e-15 55.4 0.0 2.1 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B PDEase_I PF00233.19 EQB61360.1 - 1.7e-08 34.5 12.2 0.0001 22.2 1.1 2.9 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Scm3 PF10384.9 EQB61360.1 - 0.0067 16.2 0.4 3.9 7.3 0.1 2.8 2 0 0 2 2 2 2 Centromere protein Scm3 HD PF01966.22 EQB61360.1 - 0.036 14.3 0.1 0.077 13.2 0.1 1.7 1 1 0 1 1 1 0 HD domain UDPGP PF01704.18 EQB61361.1 - 1.1e-16 60.6 0.6 1.3e-16 60.3 0.6 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EQB61361.1 - 1.1e-06 29.0 0.0 1.3e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EQB61361.1 - 0.0002 21.1 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase IspD PF01128.19 EQB61361.1 - 0.0064 16.3 0.0 0.008 15.9 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Ribosomal_L29 PF00831.23 EQB61362.1 - 3.6e-12 46.0 4.4 5.2e-12 45.6 4.4 1.2 1 0 0 1 1 1 1 Ribosomal L29 protein DUF465 PF04325.13 EQB61362.1 - 0.17 11.9 4.8 2.5 8.2 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF465) Cpn60_TCP1 PF00118.24 EQB61363.1 - 4e-100 335.8 6.4 4.7e-100 335.5 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1284 PF06935.11 EQB61363.1 - 0.053 14.0 0.4 0.35 11.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) DUF1664 PF07889.12 EQB61363.1 - 0.23 11.5 1.6 0.97 9.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) YtxH PF12732.7 EQB61364.1 - 0.0003 21.3 21.3 0.0084 16.6 3.9 3.1 2 1 1 3 3 3 3 YtxH-like protein DUF883 PF05957.13 EQB61364.1 - 0.029 15.0 12.2 0.04 14.5 1.8 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.10 EQB61364.1 - 0.21 11.7 5.4 10 6.3 0.0 3.3 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) REF PF05755.12 EQB61364.1 - 2.4 7.9 7.3 1.2 9.0 1.2 2.2 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) LIN37 PF15306.6 EQB61365.1 - 0.044 14.0 1.2 0.044 14.0 1.2 1.6 2 0 0 2 2 2 0 LIN37 DUF4430 PF14478.6 EQB61365.1 - 0.06 14.0 0.8 0.18 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) BRD4_CDT PF17105.5 EQB61365.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 SRRM_C PF15230.6 EQB61366.1 - 0.043 14.4 0.3 0.072 13.7 0.3 1.4 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus PSP1 PF04468.12 EQB61367.1 - 1.4e-29 102.2 2.1 2.3e-29 101.5 2.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region SPACA9 PF15120.6 EQB61368.1 - 0.0041 16.9 3.7 0.87 9.4 0.2 2.2 1 1 1 2 2 2 2 Sperm acrosome-associated protein 9 Sec20 PF03908.13 EQB61368.1 - 0.0052 16.7 3.9 0.018 15.0 0.1 2.5 2 1 0 2 2 2 1 Sec20 Tropomyosin_1 PF12718.7 EQB61368.1 - 0.03 14.5 4.7 0.03 14.5 4.7 2.0 1 1 1 2 2 2 0 Tropomyosin like Val_tRNA-synt_C PF10458.9 EQB61368.1 - 0.056 13.7 3.8 0.056 13.7 3.8 2.6 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm V-SNARE_C PF12352.8 EQB61368.1 - 0.065 13.5 2.1 0.19 12.1 0.5 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DctP PF03480.13 EQB61368.1 - 0.14 11.5 1.6 6.2 6.1 0.0 2.4 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 S6OS1 PF15676.5 EQB61368.1 - 0.14 10.6 8.7 0.14 10.6 8.7 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Syntaxin-6_N PF09177.11 EQB61368.1 - 0.64 10.6 6.7 0.98 10.0 2.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DPM3 PF08285.11 EQB61368.1 - 0.97 9.7 2.9 0.44 10.8 0.4 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PHM7_cyt PF14703.6 EQB61368.1 - 1.4 9.1 6.5 2 8.6 0.2 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter FlaC_arch PF05377.11 EQB61368.1 - 2 8.9 10.2 4.4 7.8 3.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 EQB61368.1 - 2.9 8.0 12.6 33 4.6 10.7 2.8 2 1 0 2 2 2 0 DivIVA protein Fzo_mitofusin PF04799.13 EQB61368.1 - 3.3 7.2 8.5 0.84 9.2 1.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region TMPIT PF07851.13 EQB61368.1 - 7.4 5.7 9.1 14 4.8 8.6 1.7 1 1 0 1 1 1 0 TMPIT-like protein HATPase_c_5 PF14501.6 EQB61368.1 - 9.3 6.2 10.4 5.9 6.9 0.1 2.8 2 1 1 3 3 3 0 GHKL domain Macoilin PF09726.9 EQB61369.1 - 1.3 7.5 30.4 1.4 7.3 30.4 1.0 1 0 0 1 1 1 0 Macoilin family Nuf2 PF03800.14 EQB61371.1 - 9.4e-17 61.4 12.7 2.3e-16 60.2 5.4 3.6 2 2 0 2 2 2 1 Nuf2 family CheZ PF04344.13 EQB61371.1 - 0.0018 18.2 0.9 0.0018 18.2 0.9 2.4 2 1 0 2 2 2 1 Chemotaxis phosphatase, CheZ DUF16 PF01519.16 EQB61371.1 - 0.006 17.0 1.5 0.006 17.0 1.5 4.3 1 1 3 4 4 3 1 Protein of unknown function DUF16 DHR10 PF18595.1 EQB61371.1 - 0.013 15.6 5.8 0.013 15.6 5.8 4.1 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain Golgin_A5 PF09787.9 EQB61371.1 - 0.057 12.9 36.9 0.035 13.6 11.2 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 APG6_N PF17675.1 EQB61371.1 - 0.1 13.1 40.4 0.037 14.6 16.1 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF2968 PF11180.8 EQB61371.1 - 0.28 10.8 6.0 2.2 7.9 3.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) DUF1664 PF07889.12 EQB61371.1 - 1.1 9.3 34.5 0.061 13.4 6.7 4.5 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 EQB61371.1 - 2.2 8.7 31.7 19 5.6 21.9 2.6 1 1 1 2 2 2 0 Fez1 HOOK PF05622.12 EQB61371.1 - 3.8 5.5 46.8 0.36 8.9 3.7 2.1 1 1 1 2 2 2 0 HOOK protein DUF4349 PF14257.6 EQB61371.1 - 5.2 6.5 6.5 15 5.0 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Sec20 PF03908.13 EQB61371.1 - 6.8 6.7 17.4 0.074 13.0 2.2 3.6 2 1 0 3 3 3 0 Sec20 Spc7 PF08317.11 EQB61371.1 - 9.9 4.9 48.0 3.4 6.5 11.6 3.6 1 1 3 4 4 4 0 Spc7 kinetochore protein Serpin PF00079.20 EQB61372.1 - 1.5e-77 261.4 17.7 1.8e-77 261.2 17.7 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DHHC PF01529.20 EQB61373.1 - 2.3e-27 95.7 18.7 3.5e-27 95.1 18.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Zf_RING PF16744.5 EQB61373.1 - 2.1 8.5 7.2 3.6 7.8 7.2 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger DHHC PF01529.20 EQB61374.1 - 1.9e-23 83.0 15.6 1.9e-23 83.0 15.6 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 EQB61375.1 - 5.8e-27 94.4 17.9 1.4e-26 93.2 17.9 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase GPR15L PF15854.5 EQB61375.1 - 8.5 6.7 11.4 3.8 7.8 1.1 2.5 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 Helicase_C PF00271.31 EQB61376.1 - 1.3e-13 51.3 0.1 1.3e-13 51.3 0.1 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF5442 PF17514.2 EQB61376.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.7 3 2 2 5 5 5 0 Family of unknown function (DUF5442) Mad3_BUB1_I_2 PF17014.5 EQB61378.1 - 1.6e-31 109.1 10.9 2e-31 108.7 10.9 1.1 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Mad3_BUB1_I PF08311.12 EQB61378.1 - 2.3e-05 24.4 2.8 3.2e-05 23.9 2.8 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 AAA_14 PF13173.6 EQB61378.1 - 0.059 13.4 1.1 0.077 13.0 0.6 1.5 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 EQB61379.1 - 3.1e-75 252.1 0.5 4.3e-75 251.7 0.5 1.1 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 EQB61379.1 - 1.8e-07 30.7 0.2 4.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EQB61379.1 - 0.00085 19.3 0.1 0.0052 16.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EQB61379.1 - 0.012 15.5 0.0 0.088 12.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EQB61379.1 - 0.031 14.7 0.1 0.047 14.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EQB61379.1 - 0.046 13.4 0.1 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM_lid PF17855.1 EQB61380.1 - 7.7e-20 71.1 0.6 1.4e-19 70.3 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_lid_2 PF17863.1 EQB61380.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA lid domain SHS2_FTSA PF02491.20 EQB61380.1 - 0.017 15.5 0.3 2.8 8.4 0.1 3.2 1 1 2 3 3 3 0 SHS2 domain inserted in FTSA DUF1694 PF07997.11 EQB61380.1 - 0.021 14.9 3.1 0.043 13.9 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1694) Sec10 PF07393.11 EQB61381.1 - 0.0011 17.5 6.5 0.0011 17.5 6.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Malate_synthase PF01274.22 EQB61381.1 - 0.055 11.7 0.0 0.088 11.0 0.0 1.2 1 0 0 1 1 1 0 Malate synthase DUF262 PF03235.14 EQB61381.1 - 0.22 11.7 8.0 0.3 11.2 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF2205 PF10224.9 EQB61381.1 - 0.62 10.1 3.5 1.8 8.6 0.1 2.8 3 0 0 3 3 3 0 Short coiled-coil protein Ribosomal_S2 PF00318.20 EQB61382.1 - 2.7e-17 62.7 0.4 1.3e-08 34.4 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 JAB PF01398.21 EQB61384.1 - 5e-21 74.9 0.0 1.3e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EQB61384.1 - 5.3e-18 65.5 0.4 9.5e-18 64.7 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function IDO PF01231.18 EQB61384.1 - 0.12 11.1 0.4 0.17 10.6 0.1 1.4 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase DUF465 PF04325.13 EQB61384.1 - 0.13 12.3 0.5 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Eaf7 PF07904.13 EQB61385.1 - 0.0001 22.6 1.7 0.0001 22.6 1.7 2.0 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 ShlB PF03865.13 EQB61385.1 - 0.022 14.2 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Autophagy_C PF10381.9 EQB61385.1 - 0.36 10.4 1.6 0.82 9.2 1.6 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Str_synth PF03088.16 EQB61386.1 - 0.0074 16.4 0.7 0.4 10.8 0.1 2.8 2 0 0 2 2 2 1 Strictosidine synthase zf-C2H2_jaz PF12171.8 EQB61386.1 - 0.14 12.5 0.5 0.14 12.5 0.5 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ThiF PF00899.21 EQB61387.1 - 6.7e-54 182.8 0.2 9.2e-54 182.4 0.2 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EQB61387.1 - 0.001 19.6 0.1 0.0037 17.8 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 EQB61387.1 - 0.0012 18.5 1.2 0.0056 16.3 1.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PI3K_p85B PF02192.16 EQB61387.1 - 0.091 12.5 1.2 0.32 10.8 0.2 2.3 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Shikimate_DH PF01488.20 EQB61387.1 - 0.13 12.3 1.4 8.2 6.5 0.1 2.4 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cytidylate_kin PF02224.18 EQB61389.1 - 2.5e-60 203.8 0.0 2.8e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 EQB61389.1 - 1.8e-07 31.4 0.1 4.2e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_18 PF13238.6 EQB61389.1 - 2.8e-07 31.2 1.7 1.4e-06 28.9 1.7 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EQB61389.1 - 0.00011 22.1 0.3 0.00095 19.1 0.3 2.1 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_17 PF13207.6 EQB61389.1 - 0.00046 20.6 0.1 0.017 15.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EQB61389.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EQB61389.1 - 0.034 14.3 0.1 0.16 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 EQB61390.1 - 0.0062 16.5 1.4 0.013 15.5 1.4 1.5 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GPI2 PF06432.11 EQB61391.1 - 2.2e-13 50.3 17.1 2.8e-13 49.9 17.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase ATP_bind_3 PF01171.20 EQB61392.1 - 2e-19 70.0 0.0 3.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 EQB61392.1 - 0.001 18.7 0.3 0.0026 17.4 0.1 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EQB61392.1 - 0.0012 17.7 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.19 EQB61392.1 - 0.0014 18.7 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.21 EQB61392.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 EQB61392.1 - 0.022 13.9 0.1 0.04 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD synthase zinc_ribbon_15 PF17032.5 EQB61392.1 - 4.9 8.0 15.6 1.5 9.6 4.0 3.3 3 0 0 3 3 3 0 zinc-ribbon family zn-ribbon_14 PF16503.5 EQB61392.1 - 5.4 6.6 16.7 0.052 13.1 2.8 3.8 4 0 0 4 4 4 0 Zinc-ribbon WD40 PF00400.32 EQB61393.1 - 0.0095 16.8 0.0 0.15 13.0 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Peptidase_M24 PF00557.24 EQB61394.1 - 1.1e-31 110.1 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EQB61394.1 - 1e-26 94.0 0.7 2.1e-26 93.0 0.7 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EQB61394.1 - 1.3e-11 44.3 0.9 2.6e-11 43.4 0.9 1.5 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 SapB_1 PF05184.15 EQB61394.1 - 6.3 6.9 9.5 5.5 7.1 1.0 2.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 RrnaAD PF00398.20 EQB61395.1 - 2.9e-57 193.7 0.1 3.4e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EQB61395.1 - 4e-07 30.7 0.0 6.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EQB61395.1 - 8e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EQB61395.1 - 0.0016 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EQB61395.1 - 0.0071 16.2 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EQB61395.1 - 0.0079 16.8 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EQB61395.1 - 0.0085 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EQB61395.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 EQB61395.1 - 0.026 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EQB61395.1 - 0.03 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 EQB61395.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase HECT PF00632.25 EQB61396.1 - 1.5e-66 225.0 6.2 2.6e-66 224.2 6.2 1.4 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Serine_protease PF18405.1 EQB61396.1 - 0.022 14.0 0.0 2.9 7.0 0.0 2.3 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Transposase_mut PF00872.18 EQB61396.1 - 0.16 10.8 2.6 0.24 10.2 2.6 1.1 1 0 0 1 1 1 0 Transposase, Mutator family RSN1_TM PF13967.6 EQB61397.1 - 2.8e-30 105.2 8.2 3.2e-30 105.0 8.2 1.0 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport GRAB PF10375.9 EQB61397.1 - 0.00072 19.3 0.0 0.0022 17.8 0.0 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain FtsH_ext PF06480.15 EQB61397.1 - 1.1 9.6 3.2 1.4 9.3 0.3 2.1 2 0 0 2 2 2 0 FtsH Extracellular Ribosomal_L7Ae PF01248.26 EQB61398.1 - 1.4e-21 76.0 1.5 1.7e-21 75.7 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF5100 PF17029.5 EQB61399.1 - 2.1e-20 72.9 9.9 2.4e-20 72.6 9.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5100) DUF1679 PF07914.11 EQB61399.1 - 0.0023 16.8 1.9 0.0027 16.6 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) BetR PF08667.10 EQB61399.1 - 0.018 15.1 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 BetR domain ER PF01133.17 EQB61399.1 - 0.048 13.7 6.0 0.46 10.5 1.7 2.1 1 1 1 2 2 2 0 Enhancer of rudimentary Tox-ART-HYE1 PF15634.6 EQB61399.1 - 0.42 9.9 6.3 0.21 10.9 3.2 1.6 1 1 1 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase DOT1 PF08123.13 EQB61400.1 - 0.0077 15.8 3.7 0.014 15.0 3.7 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 SPACA7 PF15307.6 EQB61400.1 - 1.4 9.2 9.1 0.16 12.3 1.4 2.5 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 MCM_OB PF17207.3 EQB61401.1 - 1.8e-09 37.5 0.2 3.1e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain PhnA_Zn_Ribbon PF08274.12 EQB61401.1 - 0.021 14.7 0.8 0.068 13.1 0.8 1.8 1 0 0 1 1 1 0 PhnA Zinc-Ribbon MCM PF00493.23 EQB61401.1 - 0.021 13.9 0.1 0.045 12.8 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain DNA_RNApol_7kD PF03604.13 EQB61401.1 - 0.14 11.9 0.7 0.41 10.4 0.7 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.25 EQB61402.1 - 3.2e-59 200.5 0.0 3.8e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61402.1 - 3.3e-33 115.1 0.0 4.1e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB61402.1 - 3.9e-05 23.1 0.0 6.6e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like zf-CCCH_7 PF18586.1 EQB61402.1 - 0.082 13.3 0.4 3.3 8.1 0.2 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Pkinase_fungal PF17667.1 EQB61402.1 - 0.18 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Sel1 PF08238.12 EQB61403.1 - 2.3e-15 56.7 13.1 0.00021 21.9 1.1 6.4 7 1 0 7 7 7 4 Sel1 repeat DUF5090 PF17009.5 EQB61404.1 - 1.2e-27 97.1 13.3 1.4e-27 96.9 13.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5090) DUF496 PF04363.12 EQB61404.1 - 0.043 13.8 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF496) DUF648 PF04890.13 EQB61404.1 - 1.5 8.5 9.3 0.65 9.7 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF648) Ricin_B_lectin PF00652.22 EQB61405.1 - 0.024 14.9 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Baculo_LEF-10 PF07206.11 EQB61405.1 - 0.7 10.1 3.0 0.26 11.5 0.4 1.6 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) rve PF00665.26 EQB61407.1 - 2.2e-05 24.6 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MLVIN_C PF18697.1 EQB61407.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve_3 PF13683.6 EQB61407.1 - 0.022 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain GbpA_2 PF18416.1 EQB61407.1 - 0.029 14.7 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 G10 PF01125.17 EQB61409.1 - 1.2e-29 103.0 4.4 1.3e-29 102.8 4.4 1.1 1 0 0 1 1 1 1 G10 protein Hydrolase_4 PF12146.8 EQB61411.1 - 1.5e-06 27.7 0.0 0.00017 21.0 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EQB61411.1 - 2.5e-06 27.3 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EQB61411.1 - 7e-06 26.0 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.13 EQB61411.1 - 0.00027 20.7 0.0 0.00047 19.9 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EQB61411.1 - 0.0019 18.9 0.0 0.0026 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EQB61411.1 - 0.0023 17.7 0.0 0.0085 15.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.12 EQB61411.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.11 EQB61411.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF676 PF05057.14 EQB61411.1 - 0.0057 16.2 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EQB61411.1 - 0.013 14.8 0.2 0.024 13.9 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EQB61411.1 - 0.031 13.8 0.1 0.95 9.0 0.0 2.2 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EQB61411.1 - 0.066 13.1 0.0 0.52 10.2 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase DUF4342 PF14242.6 EQB61411.1 - 0.12 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Hydrolase_4 PF12146.8 EQB61412.1 - 1.2e-06 28.0 0.0 0.00014 21.2 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EQB61412.1 - 2.2e-06 27.5 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EQB61412.1 - 6.3e-06 26.1 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.13 EQB61412.1 - 0.00023 20.9 0.0 0.00049 19.8 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EQB61412.1 - 0.0016 19.1 0.0 0.0022 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EQB61412.1 - 0.0024 17.4 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 EQB61412.1 - 0.0024 17.7 0.0 0.0077 16.0 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family VirJ PF06057.11 EQB61412.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF676 PF05057.14 EQB61412.1 - 0.0052 16.3 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EQB61412.1 - 0.013 14.8 0.2 0.022 14.1 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EQB61412.1 - 0.026 14.1 0.1 0.88 9.1 0.0 2.2 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EQB61412.1 - 0.056 13.3 0.0 0.44 10.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase DUF4342 PF14242.6 EQB61412.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Guanylate_kin PF00625.21 EQB61413.1 - 1.1e-19 70.8 2.8 1.1e-19 70.8 2.8 2.4 2 1 0 2 2 2 1 Guanylate kinase AAA_18 PF13238.6 EQB61413.1 - 2e-06 28.4 1.3 4.9e-06 27.1 0.3 2.2 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.6 EQB61413.1 - 5.3e-05 23.8 1.7 0.00027 21.5 1.7 2.1 1 1 0 1 1 1 1 AAA domain zf-CCCH PF00642.24 EQB61413.1 - 0.00036 20.4 12.1 0.00097 19.0 1.4 2.6 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Thymidylate_kin PF02223.17 EQB61413.1 - 0.0014 18.4 1.6 0.76 9.4 0.1 2.6 3 0 0 3 3 2 2 Thymidylate kinase AAA_22 PF13401.6 EQB61413.1 - 0.0021 18.3 0.0 0.0084 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EQB61413.1 - 0.0033 17.4 0.3 0.0078 16.1 0.0 1.8 2 0 0 2 2 1 1 NTPase MMR_HSR1 PF01926.23 EQB61413.1 - 0.0041 17.2 1.2 0.0073 16.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EQB61413.1 - 0.0041 17.5 0.1 0.016 15.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EQB61413.1 - 0.0042 17.0 2.0 0.3 11.0 0.0 2.7 2 1 0 2 2 2 1 NACHT domain zf-CCCH_3 PF15663.5 EQB61413.1 - 0.0057 16.9 11.7 0.0088 16.2 10.7 1.9 1 1 1 2 2 2 1 Zinc-finger containing family AAA_29 PF13555.6 EQB61413.1 - 0.0066 16.2 0.3 0.012 15.3 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 EQB61413.1 - 0.0089 15.6 0.3 0.025 14.2 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EQB61413.1 - 0.011 15.2 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EQB61413.1 - 0.013 16.1 1.7 0.017 15.6 0.0 2.0 2 1 0 2 2 2 0 ABC transporter zf-CCCH_4 PF18044.1 EQB61413.1 - 0.013 15.3 3.0 0.013 15.3 3.0 3.1 2 1 0 2 2 2 0 CCCH-type zinc finger SMC_ScpA PF02616.14 EQB61413.1 - 0.016 15.2 1.3 0.02 14.8 0.2 1.7 2 0 0 2 2 2 0 Segregation and condensation protein ScpA ATPase_2 PF01637.18 EQB61413.1 - 0.016 15.1 4.9 0.019 14.9 1.1 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EQB61413.1 - 0.017 15.4 0.7 0.055 13.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EQB61413.1 - 0.018 15.4 0.1 0.072 13.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase zf_CCCH_4 PF18345.1 EQB61413.1 - 0.021 14.9 4.3 0.021 14.9 4.3 3.4 2 1 0 2 2 2 0 Zinc finger domain AAA_16 PF13191.6 EQB61413.1 - 0.024 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EQB61413.1 - 0.024 14.8 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EQB61413.1 - 0.029 14.4 0.2 0.067 13.2 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EQB61413.1 - 0.032 14.7 0.1 0.77 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EQB61413.1 - 0.045 13.7 0.5 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 EQB61413.1 - 0.047 12.7 0.6 0.099 11.7 0.6 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EQB61413.1 - 0.058 13.6 0.4 0.28 11.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EQB61413.1 - 0.099 12.5 0.2 0.25 11.2 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.12 EQB61413.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EQB61413.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EQB61413.1 - 0.13 11.4 2.0 0.22 10.7 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EQB61413.1 - 0.14 12.2 0.1 0.92 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3847 PF12958.7 EQB61413.1 - 0.17 12.1 0.8 0.31 11.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) AAA_14 PF13173.6 EQB61413.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Fur_reg_FbpB PF13040.6 EQB61413.1 - 1 9.0 7.5 8.2 6.1 0.1 3.5 3 0 0 3 3 3 0 Fur-regulated basic protein B MAT1 PF06391.13 EQB61415.1 - 6.9e-17 62.0 11.1 8.7e-17 61.6 11.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EQB61415.1 - 8.1e-13 48.0 8.4 8.1e-13 48.0 8.4 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EQB61415.1 - 0.00068 19.9 7.1 0.00068 19.9 7.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB61415.1 - 0.00077 19.3 6.8 0.00077 19.3 6.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EQB61415.1 - 0.0011 19.0 8.6 0.0025 17.8 8.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EQB61415.1 - 0.0024 17.8 9.9 0.0024 17.8 9.9 2.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EQB61415.1 - 0.0063 16.4 10.0 0.0063 16.4 10.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_L37e PF01907.19 EQB61415.1 - 0.021 15.0 2.2 0.021 15.0 2.2 1.8 2 0 0 2 2 2 0 Ribosomal protein L37e Prok-RING_4 PF14447.6 EQB61415.1 - 0.28 11.1 11.2 0.82 9.6 4.0 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3889 PF13028.6 EQB61416.1 - 0.015 15.2 0.2 0.034 14.1 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3889) Ricin_B_lectin PF00652.22 EQB61417.1 - 0.037 14.3 0.1 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 EQB61420.1 - 1.3e-06 28.7 0.5 5.3e-06 26.7 0.4 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ribosomal_L11 PF00298.19 EQB61421.1 - 1.9e-14 53.9 0.1 5.4e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EQB61421.1 - 1.7e-13 50.2 0.6 5e-13 48.7 0.6 1.8 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain LpxC PF03331.13 EQB61421.1 - 0.023 14.2 0.0 0.026 14.0 0.0 1.0 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase PAH PF02671.21 EQB61422.1 - 9e-09 35.3 0.4 2e-08 34.3 0.4 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat Pkinase PF00069.25 EQB61423.1 - 2.3e-48 164.9 0.1 3.1e-48 164.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61423.1 - 6.3e-21 74.8 0.0 1.3e-20 73.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EQB61423.1 - 0.001 18.7 0.1 0.0074 15.9 0.1 2.1 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EQB61423.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EQB61423.1 - 0.0037 16.9 0.3 0.0099 15.5 0.3 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EQB61423.1 - 0.022 14.4 0.2 3.4 7.2 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EQB61423.1 - 0.035 13.5 0.2 0.063 12.6 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TIM PF00121.18 EQB61424.1 - 1.4e-52 178.5 0.0 1.7e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Xpo1 PF08389.12 EQB61425.1 - 7.6e-18 65.0 2.2 2.1e-17 63.5 0.2 2.0 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EQB61425.1 - 6.2e-09 35.6 0.9 1.3e-08 34.7 0.6 1.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat_2 PF18784.1 EQB61426.1 - 9.6e-23 79.6 0.6 2.6e-22 78.2 0.6 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EQB61426.1 - 1.5e-21 76.2 3.4 1.5e-21 76.2 3.4 4.1 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EQB61426.1 - 1.9e-08 33.7 4.3 1.9e-07 30.5 0.9 3.0 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat Xpo1 PF08389.12 EQB61426.1 - 1e-05 25.6 0.6 1e-05 25.6 0.6 3.7 3 2 0 4 4 4 1 Exportin 1-like protein DUF2779 PF11074.8 EQB61426.1 - 0.19 12.2 3.5 0.39 11.2 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) Vac14_Fab1_bd PF12755.7 EQB61426.1 - 0.2 12.2 6.1 0.76 10.4 0.2 3.4 2 2 1 3 3 3 0 Vacuolar 14 Fab1-binding region TFIID-18kDa PF02269.16 EQB61427.1 - 5.5e-22 77.6 0.7 6.4e-22 77.4 0.7 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF3801 PF12687.7 EQB61427.1 - 0.057 13.5 4.1 0.57 10.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) Arc_trans_TRASH PF08394.10 EQB61428.1 - 0.13 12.6 0.4 0.35 11.2 0.4 1.7 1 0 0 1 1 1 0 Archaeal TRASH domain MAT1 PF06391.13 EQB61429.1 - 8.7e-16 58.4 11.5 8.7e-16 58.4 11.5 1.3 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EQB61429.1 - 1.3e-12 47.4 8.4 1.3e-12 47.4 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB61429.1 - 0.00059 19.7 9.6 0.0033 17.4 9.7 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EQB61429.1 - 0.00067 19.5 7.6 0.0022 17.8 7.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EQB61429.1 - 0.0011 19.3 7.1 0.0011 19.3 7.1 2.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EQB61429.1 - 0.0014 18.6 8.6 0.004 17.2 8.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EQB61429.1 - 0.01 15.7 10.0 0.01 15.7 10.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L37e PF01907.19 EQB61429.1 - 0.031 14.4 2.2 0.031 14.4 2.2 2.3 3 0 0 3 3 3 0 Ribosomal protein L37e Prok-RING_4 PF14447.6 EQB61429.1 - 0.46 10.4 11.1 1.1 9.1 3.8 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Ca_chan_IQ PF08763.11 EQB61430.1 - 0.44 10.8 5.3 0.23 11.7 2.0 1.9 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain PSP PF04046.16 EQB61431.1 - 7.6e-20 70.5 0.7 1.5e-19 69.6 0.3 1.7 2 0 0 2 2 2 1 PSP DUF382 PF04037.13 EQB61431.1 - 1.8e-16 60.5 0.9 1.8e-16 60.5 0.9 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF382) ICA69 PF04629.14 EQB61431.1 - 3.2 8.0 7.7 17 5.6 8.1 1.9 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain Pkinase PF00069.25 EQB61432.1 - 1.7e-51 175.2 2.2 2e-51 174.9 2.1 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61432.1 - 1e-37 129.8 0.4 1.2e-37 129.6 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EQB61432.1 - 6.6e-06 25.2 0.0 3.7e-05 22.7 0.0 1.8 1 1 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EQB61432.1 - 0.0064 16.1 0.1 0.76 9.4 0.1 2.7 2 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIC3 PF15361.6 EQB61432.1 - 0.13 12.7 0.5 0.29 11.5 0.5 1.6 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Methyltransf_4 PF02390.17 EQB61433.1 - 6.3e-29 100.6 1.3 1e-27 96.7 1.3 2.0 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EQB61433.1 - 7.1e-08 32.4 0.2 9.2e-08 32.0 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EQB61433.1 - 3.8e-07 30.7 0.0 5.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EQB61433.1 - 9.3e-06 26.2 0.0 1.6e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EQB61433.1 - 1.2e-05 24.8 0.1 2e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EQB61433.1 - 7.2e-05 22.4 0.1 0.00034 20.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EQB61433.1 - 0.0001 23.0 0.0 0.00017 22.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EQB61433.1 - 0.00016 20.8 0.0 0.00036 19.7 0.0 1.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DOT1 PF08123.13 EQB61433.1 - 0.00077 19.0 1.8 0.036 13.6 0.0 2.1 1 1 1 2 2 2 2 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 EQB61433.1 - 0.0017 18.2 0.0 0.0066 16.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EQB61433.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EQB61433.1 - 0.033 14.5 0.1 0.097 13.0 0.0 1.8 2 1 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase HisK_sensor PF18698.1 EQB61433.1 - 0.034 14.5 2.4 0.098 13.0 0.3 2.2 1 1 1 2 2 2 0 Histidine kinase sensor domain Methyltransf_9 PF08003.11 EQB61433.1 - 0.038 12.9 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EQB61433.1 - 0.04 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GidB PF02527.15 EQB61433.1 - 0.043 13.1 0.0 0.059 12.7 0.0 1.3 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 EQB61433.1 - 0.06 13.3 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cation_efflux PF01545.21 EQB61434.1 - 3.4e-42 144.4 19.8 3.4e-42 144.4 19.8 1.5 2 0 0 2 2 2 1 Cation efflux family GtrA PF04138.14 EQB61434.1 - 1.3 9.2 11.7 0.2 11.9 7.0 2.1 2 1 0 2 2 2 0 GtrA-like protein TctB PF07331.11 EQB61434.1 - 9.7 6.5 11.2 32 4.8 11.1 2.0 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Syntaxin PF00804.25 EQB61435.1 - 9.9e-09 35.2 14.3 9.9e-09 35.2 14.3 1.4 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 EQB61435.1 - 3.2e-06 27.0 4.9 4.9e-06 26.4 0.5 2.5 2 0 0 2 2 2 1 SNARE domain DUF948 PF06103.11 EQB61435.1 - 0.0014 18.8 1.3 0.0014 18.8 1.3 3.0 3 1 0 3 3 3 2 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 EQB61435.1 - 0.0031 16.7 1.6 0.0031 16.7 1.6 2.5 2 1 0 2 2 2 1 Autophagy protein Apg17 LXG PF04740.12 EQB61435.1 - 0.039 13.7 19.7 0.02 14.6 11.0 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Med2 PF11214.8 EQB61435.1 - 0.075 13.2 13.3 0.056 13.6 8.9 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 zf-XS PF03470.14 EQB61435.1 - 0.088 13.1 1.0 0.18 12.1 1.0 1.5 1 0 0 1 1 1 0 XS zinc finger domain TMEM191C PF15194.6 EQB61435.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 TMEM191C family DUF349 PF03993.12 EQB61435.1 - 0.37 11.1 0.2 0.37 11.1 0.2 3.1 3 1 0 3 3 3 0 Domain of Unknown Function (DUF349) Baculo_PEP_C PF04513.12 EQB61435.1 - 1.4 9.0 9.1 0.13 12.3 1.6 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.13 EQB61435.1 - 2 7.0 6.9 1.1 7.8 2.9 2.0 2 0 0 2 2 2 0 Tweety Topoisom_I_N PF02919.15 EQB61435.1 - 2.2 7.7 9.9 4 6.9 9.6 1.6 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment NPV_P10 PF05531.12 EQB61435.1 - 2.9 8.4 6.6 1.3 9.6 1.4 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 EQB61435.1 - 2.9 8.3 14.9 0.22 11.9 6.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Folliculin PF11704.8 EQB61435.1 - 9.7 6.0 9.3 2.3 8.1 3.4 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport AP_endonuc_2 PF01261.24 EQB61436.1 - 1.1e-29 103.3 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Prolamin_like PF05617.11 EQB61436.1 - 0.001 19.2 0.6 0.77 10.0 0.1 2.7 2 0 0 2 2 2 2 Prolamin-like ParcG PF10274.9 EQB61437.1 - 0.003 17.7 0.3 0.0036 17.5 0.3 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DUF5352 PF17303.2 EQB61437.1 - 0.019 14.8 0.3 0.023 14.6 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5352) DUF992 PF06186.11 EQB61437.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF992) LAGLIDADG_1 PF00961.19 EQB61437.1 - 1.3 10.0 11.7 0.81 10.7 3.4 2.7 1 1 2 3 3 3 0 LAGLIDADG endonuclease gag-asp_proteas PF13975.6 EQB61438.1 - 3.2e-12 46.8 0.0 6.7e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EQB61438.1 - 7.7e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EQB61438.1 - 2.3e-06 27.4 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EQB61438.1 - 3.7e-06 27.2 0.0 2.2e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 EQB61438.1 - 1.7e-05 24.6 0.1 3.6e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Sad1_UNC PF07738.13 EQB61439.1 - 2.2e-17 63.3 1.9 2.2e-17 63.3 1.9 2.1 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal ABC_tran PF00005.27 EQB61440.1 - 4.1e-37 127.8 0.1 6.3e-18 65.6 0.1 2.7 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 EQB61440.1 - 1.8e-08 34.1 2.6 1.8e-08 34.1 2.6 2.9 3 0 0 3 3 3 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EQB61440.1 - 2.1e-08 34.3 13.7 0.12 12.2 1.1 4.5 3 2 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EQB61440.1 - 9.8e-08 31.7 8.7 0.001 18.5 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA PF00004.29 EQB61440.1 - 7.5e-07 29.6 0.0 0.024 15.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EQB61440.1 - 4.3e-06 26.7 0.4 0.0062 16.5 0.1 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_23 PF13476.6 EQB61440.1 - 1.1e-05 26.1 3.2 0.012 16.1 0.3 2.7 1 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EQB61440.1 - 2.2e-05 23.8 0.1 0.028 13.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 EQB61440.1 - 2.3e-05 24.8 0.0 0.0085 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4 PF00037.27 EQB61440.1 - 5.4e-05 22.8 4.5 5.4e-05 22.8 4.5 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.12 EQB61440.1 - 0.00011 22.2 0.8 0.06 13.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 EQB61440.1 - 0.00047 19.8 1.5 0.087 12.6 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EQB61440.1 - 0.0017 18.7 0.1 2.8 8.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 EQB61440.1 - 0.0017 18.0 1.3 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EQB61440.1 - 0.0029 18.0 0.3 2.3 8.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EQB61440.1 - 0.0052 16.7 0.1 0.071 13.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 EQB61440.1 - 0.0074 16.2 1.6 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 NTPase RuvB_N PF05496.12 EQB61440.1 - 0.0094 15.7 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EQB61440.1 - 0.01 15.8 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EQB61440.1 - 0.015 15.9 0.3 0.32 11.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 EQB61440.1 - 0.016 15.3 4.5 0.016 15.3 4.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_15 PF13175.6 EQB61440.1 - 0.017 14.9 16.2 0.3 10.7 3.7 3.2 1 1 1 2 2 2 0 AAA ATPase domain Fer4_6 PF12837.7 EQB61440.1 - 0.021 14.9 4.3 0.021 14.9 4.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_24 PF13479.6 EQB61440.1 - 0.023 14.4 0.5 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EQB61440.1 - 0.043 13.8 0.1 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_21 PF14697.6 EQB61440.1 - 0.068 13.3 16.7 0.14 12.3 16.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain DnaB_C PF03796.15 EQB61440.1 - 0.083 12.2 0.0 0.73 9.1 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fer4_9 PF13187.6 EQB61440.1 - 0.1 12.8 19.2 0.21 11.8 19.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 EQB61440.1 - 0.1 12.3 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_28 PF13521.6 EQB61440.1 - 0.11 12.8 0.5 13 6.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Antimicrobial14 PF08109.11 EQB61440.1 - 0.11 12.6 0.3 8.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Lactocin 705 family AAA_33 PF13671.6 EQB61440.1 - 0.12 12.5 0.3 25 5.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EQB61440.1 - 0.13 12.5 1.6 1.8 8.8 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Fer4_2 PF12797.7 EQB61440.1 - 0.18 12.0 10.7 0.071 13.2 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_30 PF13604.6 EQB61440.1 - 0.23 11.2 0.2 27 4.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EQB61440.1 - 0.28 10.9 1.5 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EQB61440.1 - 0.3 11.1 3.5 16 5.5 0.1 3.5 2 2 1 3 3 3 0 AAA domain MobB PF03205.14 EQB61440.1 - 0.37 10.7 2.4 17 5.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_7 PF12838.7 EQB61440.1 - 0.42 11.2 15.6 1.9 9.1 16.0 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-CHY PF05495.12 EQB61441.1 - 1.9e-11 44.3 12.0 1.9e-11 44.3 12.0 3.3 3 0 0 3 3 3 1 CHY zinc finger DUF4348 PF14254.6 EQB61442.1 - 0.015 14.7 3.6 0.016 14.6 2.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4348) PseudoU_synth_1 PF01416.20 EQB61443.1 - 5.5e-09 36.4 0.0 1.7e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 tRNA pseudouridine synthase Ribosomal_S19e PF01090.19 EQB61444.1 - 1.3e-15 57.3 0.0 6.4e-09 35.6 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S19e Pho88 PF10032.9 EQB61445.1 - 7.6e-28 97.0 3.6 8.9e-28 96.8 3.6 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) BatD PF13584.6 EQB61445.1 - 0.058 12.2 0.1 0.068 12.0 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance NAP PF00956.18 EQB61446.1 - 0.0073 15.5 4.0 0.0096 15.1 1.1 1.9 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) PET10 PF17316.2 EQB61446.1 - 0.037 13.6 0.2 0.048 13.2 0.1 1.2 1 1 0 1 1 1 0 Petite colonies protein 10 RRF_GI PF12614.8 EQB61446.1 - 0.064 13.4 0.2 0.078 13.1 0.2 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Homeodomain PF00046.29 EQB61448.1 - 1.6e-12 47.1 1.0 2.2e-12 46.6 1.0 1.3 1 0 0 1 1 1 1 Homeodomain YgbB PF02542.16 EQB61448.1 - 0.0085 16.4 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 YgbB family Homeobox_KN PF05920.11 EQB61448.1 - 0.25 11.3 0.2 0.25 11.3 0.2 1.6 2 0 0 2 2 2 0 Homeobox KN domain RL PF17797.1 EQB61449.1 - 0.036 14.0 0.5 0.036 14.0 0.5 3.3 4 0 0 4 4 4 0 RL domain EF-hand_13 PF17958.1 EQB61449.1 - 0.57 10.0 6.0 0.98 9.3 0.2 3.3 3 0 0 3 3 3 0 EF-hand domain zf-RVT PF13966.6 EQB61450.1 - 0.12 13.2 1.7 0.24 12.2 0.6 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase TraF PF13728.6 EQB61450.1 - 0.17 11.7 0.2 0.79 9.5 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein BsuBI_PstI_RE PF06616.11 EQB61450.1 - 0.18 11.1 2.0 1 8.7 0.4 2.4 2 1 0 3 3 3 0 BsuBI/PstI restriction endonuclease domain RVT_1 PF00078.27 EQB61451.1 - 3.5e-32 111.7 0.2 4.5e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CofC PF01983.16 EQB61451.1 - 0.022 13.9 0.1 0.088 12.0 0.0 1.8 2 0 0 2 2 2 0 Guanylyl transferase CofC like GerPE PF10970.8 EQB61452.1 - 0.0071 16.5 4.1 0.027 14.7 0.1 2.5 2 1 1 3 3 3 1 Spore germination protein GerPE TORC_N PF12884.7 EQB61452.1 - 0.018 15.8 3.5 11 6.8 0.0 3.7 4 0 0 4 4 4 0 Transducer of regulated CREB activity, N terminus LacI PF00356.21 EQB61452.1 - 0.49 10.2 0.1 0.49 10.2 0.1 2.4 4 0 0 4 4 4 0 Bacterial regulatory proteins, lacI family DUF3685 PF12452.8 EQB61455.1 - 0.019 14.6 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) ABC_membrane_3 PF13748.6 EQB61457.1 - 0.17 11.1 2.1 0.32 10.2 0.2 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region MFS_1_like PF12832.7 EQB61458.1 - 2.6e-21 75.9 14.2 1.1e-20 73.9 11.6 2.5 2 1 0 2 2 2 1 MFS_1 like family ATP-synt_I PF03899.15 EQB61458.1 - 0.061 13.7 1.2 0.061 13.7 1.2 2.4 2 1 0 2 2 2 0 ATP synthase I chain MFS_1 PF07690.16 EQB61458.1 - 0.4 9.6 12.4 0.4 9.6 5.4 2.9 1 1 1 2 2 2 0 Major Facilitator Superfamily HEAT PF02985.22 EQB61461.1 - 0.00038 20.5 0.5 1.1 9.7 0.1 3.3 3 0 0 3 3 3 2 HEAT repeat RTP1_C1 PF10363.9 EQB61461.1 - 0.0026 17.9 2.0 0.0082 16.3 0.6 2.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EQB61461.1 - 0.01 16.2 0.0 1.1 9.8 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats MitMem_reg PF13012.6 EQB61461.1 - 0.046 14.2 1.0 0.087 13.2 1.0 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function tRNA_anti-codon PF01336.25 EQB61462.1 - 1.8e-09 37.5 0.1 3.5e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Poxvirus PF06227.12 EQB61462.1 - 0.023 14.5 10.9 0.042 13.6 10.9 1.4 1 1 0 1 1 1 0 dsDNA Poxvirus RPA_C PF08784.11 EQB61462.1 - 0.075 13.7 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal TFIIE_beta PF02186.15 EQB61463.1 - 6.7e-10 39.1 4.1 6.7e-10 39.1 4.1 2.5 3 1 0 3 3 3 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 EQB61463.1 - 0.00015 21.4 5.4 0.00071 19.2 1.4 3.0 2 1 0 2 2 2 1 TFA2 Winged helix domain 2 HTH_micro PF17007.5 EQB61463.1 - 0.00057 18.8 9.3 0.00057 18.8 9.3 1.4 1 1 0 1 1 1 1 HTH-like Imm68 PF15583.6 EQB61463.1 - 0.015 15.5 4.8 0.026 14.7 4.8 1.3 1 0 0 1 1 1 0 Immunity protein 68 DUF1732 PF08340.11 EQB61463.1 - 0.021 14.8 0.1 0.021 14.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) APG12 PF04110.13 EQB61463.1 - 0.069 13.6 0.8 0.48 10.9 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 MCM PF00493.23 EQB61464.1 - 8.1e-68 227.9 0.0 1.6e-67 226.9 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EQB61464.1 - 8.9e-29 99.8 1.3 1.6e-28 99.0 1.3 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EQB61464.1 - 0.00014 21.3 0.0 0.00026 20.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 EQB61464.1 - 0.0043 17.7 0.1 0.017 15.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EQB61464.1 - 0.0047 16.8 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_OB PF17207.3 EQB61465.1 - 7.3e-32 109.9 0.5 1.1e-31 109.3 0.5 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 EQB61465.1 - 1.9e-11 44.4 2.3 5.5e-11 43.0 2.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.23 EQB61465.1 - 0.0078 15.3 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain Rotamase PF00639.21 EQB61466.1 - 5.8e-23 81.7 0.0 8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EQB61466.1 - 9e-20 71.4 0.0 1.4e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EQB61466.1 - 2.9e-05 24.9 0.0 5.7e-05 24.0 0.0 1.6 2 1 0 2 2 2 1 PPIC-type PPIASE domain WW PF00397.26 EQB61466.1 - 0.0076 16.3 1.5 0.014 15.5 1.5 1.5 1 0 0 1 1 1 1 WW domain RNA_pol_N PF01194.17 EQB61467.1 - 4.3e-16 59.0 0.3 5.4e-16 58.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit MBD PF01429.19 EQB61467.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Methyl-CpG binding domain Chordopox_RPO7 PF05864.12 EQB61467.1 - 0.042 14.1 0.1 0.062 13.6 0.0 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) YhfH PF14149.6 EQB61467.1 - 0.058 13.4 0.5 0.1 12.6 0.5 1.4 1 0 0 1 1 1 0 YhfH-like protein WD40 PF00400.32 EQB61468.1 - 8.2e-18 64.4 8.8 1.5e-05 25.7 0.1 5.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB61468.1 - 4.6e-06 26.8 0.6 2.1 8.7 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EQB61468.1 - 0.00013 21.4 8.2 0.0054 16.1 5.4 2.5 1 1 1 2 2 2 2 WD40-like domain Baculo_FP PF03258.14 EQB61468.1 - 0.12 12.6 1.8 1 9.5 1.8 2.3 1 1 0 1 1 1 0 Baculovirus FP protein Helicase_C PF00271.31 EQB61469.1 - 5.3e-21 75.0 0.1 2.1e-20 73.1 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EQB61470.1 - 6.9e-39 133.5 0.0 1.3e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF29 PF01724.16 EQB61470.1 - 0.013 15.8 0.7 0.073 13.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF29 SWI2_SNF2 PF18766.1 EQB61470.1 - 0.048 13.3 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DEAD PF00270.29 EQB61470.1 - 0.063 13.1 0.1 0.58 9.9 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase HEAT_2 PF13646.6 EQB61471.1 - 2.6e-06 27.7 0.0 0.0093 16.3 0.0 2.4 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.22 EQB61471.1 - 7.2e-05 22.7 0.0 11 6.6 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Rsd_AlgQ PF04353.13 EQB61471.1 - 0.0078 16.2 0.8 0.41 10.6 1.1 3.2 3 0 0 3 3 3 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GDI PF00996.18 EQB61472.1 - 2.8e-59 200.8 2.7 3.3e-59 200.5 2.7 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox PF00070.27 EQB61472.1 - 0.015 15.8 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EQB61472.1 - 0.036 13.6 0.0 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3969 PF13108.6 EQB61472.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3969) Shikimate_DH PF01488.20 EQB61472.1 - 0.054 13.6 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M24 PF00557.24 EQB61472.1 - 0.065 12.9 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 NAD_binding_8 PF13450.6 EQB61472.1 - 0.094 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.18 EQB61473.1 - 2.1e-27 95.7 0.5 2.4e-27 95.6 0.5 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor CST-I PF06002.12 EQB61474.1 - 0.0057 16.4 0.4 0.0057 16.4 0.4 1.5 2 0 0 2 2 2 1 Alpha-2,3-sialyltransferase (CST-I) DUF755 PF05501.11 EQB61474.1 - 0.13 12.5 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ATP_bind_1 PF03029.17 EQB61475.1 - 5.8e-53 180.1 0.2 8.7e-53 179.6 0.2 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EQB61475.1 - 1.9e-06 27.9 0.4 0.18 11.7 0.1 3.2 3 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EQB61475.1 - 1.9e-05 24.3 0.0 9.8e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EQB61475.1 - 2.3e-05 24.0 0.0 0.0001 22.0 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EQB61475.1 - 0.00014 21.6 0.0 0.0039 16.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 EQB61475.1 - 0.00026 21.5 0.4 0.00068 20.2 0.1 1.9 1 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 EQB61475.1 - 0.00048 20.2 0.0 0.0053 16.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EQB61475.1 - 0.00087 19.6 0.0 0.0029 17.9 0.0 1.9 2 1 1 3 3 3 1 AAA domain Gtr1_RagA PF04670.12 EQB61475.1 - 0.00089 18.7 0.5 0.041 13.2 0.1 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NACHT PF05729.12 EQB61475.1 - 0.0013 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 EQB61475.1 - 0.0017 17.8 0.2 1.6 8.1 0.1 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family NB-ARC PF00931.22 EQB61475.1 - 0.0021 17.3 0.1 0.0048 16.1 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EQB61475.1 - 0.0026 17.5 0.3 0.0081 15.9 0.1 1.8 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EQB61475.1 - 0.0034 16.8 0.2 1.1 8.6 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EQB61475.1 - 0.0062 16.9 0.0 0.015 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 EQB61475.1 - 0.011 15.6 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 EQB61475.1 - 0.018 15.2 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EQB61475.1 - 0.021 14.3 0.7 0.087 12.3 0.0 2.1 2 1 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.9 EQB61475.1 - 0.022 14.5 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 EQB61475.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Thymidylate_kin PF02223.17 EQB61475.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase PIF1 PF05970.14 EQB61475.1 - 0.04 13.1 0.2 0.076 12.2 0.1 1.5 2 0 0 2 2 2 0 PIF1-like helicase DUF87 PF01935.17 EQB61475.1 - 0.057 13.5 0.6 1.1 9.3 0.1 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain MobB PF03205.14 EQB61475.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EQB61475.1 - 0.069 12.9 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EQB61475.1 - 0.094 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EQB61475.1 - 0.096 12.9 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 EQB61475.1 - 0.1 12.4 0.1 4.7 7.0 0.1 2.9 2 1 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 EQB61475.1 - 0.1 12.6 0.1 0.37 10.8 0.1 2.1 2 1 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EQB61475.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EQB61475.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EQB61475.1 - 0.17 12.4 1.7 0.29 11.6 1.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EQB61475.1 - 0.65 9.7 7.8 1 9.0 7.9 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 EQB61476.1 - 1.4e-38 133.0 0.2 1.6e-38 132.9 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EQB61476.1 - 0.0017 17.9 0.1 0.0076 15.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EQB61476.1 - 0.0021 18.0 0.1 0.083 12.8 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase DUF5587 PF17825.1 EQB61476.1 - 0.015 12.6 0.6 0.019 12.3 0.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) SLIDE PF09111.10 EQB61476.1 - 0.073 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 SLIDE DUF459 PF04311.13 EQB61476.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF459) MMR_HSR1 PF01926.23 EQB61476.1 - 0.15 12.2 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M48 PF01435.18 EQB61477.1 - 6.2e-37 127.3 0.0 6.2e-37 127.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 EQB61477.1 - 1.2e-33 116.5 21.6 1.2e-33 116.5 21.6 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices SprT-like PF10263.9 EQB61477.1 - 0.00042 20.1 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_M56 PF05569.11 EQB61477.1 - 0.0036 16.6 8.9 0.0036 16.6 8.9 1.6 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF2268 PF10026.9 EQB61477.1 - 0.0039 16.8 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF4538 PF15061.6 EQB61477.1 - 0.029 14.1 0.1 0.1 12.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ribosomal_L7Ae PF01248.26 EQB61478.1 - 3.6e-11 42.6 0.1 4.4e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Spc24 PF08286.11 EQB61479.1 - 0.0012 19.0 5.8 0.0012 19.0 5.8 1.8 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 NUC153 PF08159.12 EQB61480.1 - 1.8e-05 24.4 0.2 4.1e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 NUC153 domain Staphylokinase PF02821.16 EQB61480.1 - 0.044 14.2 5.9 0.061 13.8 5.9 1.4 1 1 0 1 1 1 0 Staphylokinase/Streptokinase family LRR_4 PF12799.7 EQB61484.1 - 0.00062 20.1 26.7 0.1 13.1 0.3 5.1 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB61484.1 - 8.2 6.3 30.3 0.12 12.1 4.8 4.4 3 1 2 5 5 5 0 Leucine rich repeat Fun_ATP-synt_8 PF05933.13 EQB61485.1 - 0.16 12.1 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) Ribosomal_L37ae PF01780.19 EQB61486.1 - 3.7e-35 119.9 7.6 4.1e-35 119.7 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 EQB61486.1 - 0.0012 19.2 1.3 0.05 14.1 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double domain OrfB_Zn_ribbon PF07282.11 EQB61486.1 - 0.019 14.9 2.9 0.026 14.5 0.8 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-like PF04071.12 EQB61486.1 - 0.022 14.7 0.3 0.043 13.7 0.2 1.5 1 1 0 1 1 1 0 Cysteine-rich small domain zf-IS66 PF13005.7 EQB61486.1 - 0.025 15.0 2.1 0.4 11.1 0.4 2.2 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 HypA PF01155.19 EQB61486.1 - 0.033 14.2 0.1 0.038 14.0 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 EQB61486.1 - 0.044 13.8 2.5 0.073 13.1 2.5 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like C1_2 PF03107.16 EQB61486.1 - 0.049 14.0 1.5 0.086 13.2 1.4 1.4 1 1 0 1 1 1 0 C1 domain zf-RING_13 PF17977.1 EQB61486.1 - 0.052 13.7 1.4 0.067 13.3 1.4 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rep_fac-A_C PF08646.10 EQB61486.1 - 0.13 12.1 3.3 1.8 8.3 1.1 2.0 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-BED PF02892.15 EQB61486.1 - 0.26 11.3 5.0 20 5.3 5.0 2.3 1 1 0 1 1 1 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 EQB61486.1 - 0.33 11.0 5.5 3.1 7.9 1.1 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin_2 PF18073.1 EQB61486.1 - 0.38 10.5 4.3 2.4 7.9 4.3 2.0 1 1 0 1 1 1 0 Rubredoxin metal binding domain zf-CCHC_2 PF13696.6 EQB61486.1 - 1.8 8.5 4.1 0.58 10.0 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle bZIP_Maf PF03131.17 EQB61488.1 - 0.0084 16.6 1.3 0.0084 16.6 1.3 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor RRM_1 PF00076.22 EQB61490.1 - 7.3e-13 48.1 0.8 3.7e-06 26.7 0.3 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.22 EQB61491.1 - 5.6e-07 29.3 0.2 0.58 10.6 0.0 6.8 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EQB61491.1 - 1.4e-06 28.6 0.0 0.72 10.3 0.0 4.7 3 2 2 5 5 5 2 HEAT repeats Tox-HDC PF15656.6 EQB61491.1 - 0.3 11.3 0.1 0.3 11.3 0.1 1.9 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature KH_6 PF15985.5 EQB61492.1 - 0.0011 19.2 0.1 0.0021 18.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Ras PF00071.22 EQB61493.1 - 1.4e-44 151.5 3.4 7.9e-44 149.1 3.4 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EQB61493.1 - 1.5e-35 122.0 0.6 2.7e-35 121.2 0.6 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB61493.1 - 8.5e-18 64.4 1.4 9.6e-18 64.2 1.4 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EQB61493.1 - 3.6e-10 39.6 1.6 4.3e-10 39.4 1.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EQB61493.1 - 5e-10 39.5 0.5 8.3e-10 38.8 0.5 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EQB61493.1 - 2e-07 30.8 1.0 6.8e-07 29.0 0.9 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EQB61493.1 - 4.4e-07 29.5 1.4 5.6e-07 29.2 1.4 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EQB61493.1 - 7.2e-05 22.7 0.7 0.065 13.1 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EQB61493.1 - 0.00074 18.8 9.8 0.49 9.5 0.0 2.9 1 1 1 2 2 2 2 G-protein alpha subunit TniB PF05621.11 EQB61493.1 - 0.0046 16.4 0.1 0.0078 15.6 0.1 1.4 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 EQB61493.1 - 0.0091 15.3 0.7 0.014 14.7 0.7 1.4 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EQB61493.1 - 0.013 15.7 0.1 0.44 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 EQB61493.1 - 0.018 15.1 2.9 0.042 13.8 0.8 2.2 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain PriX PF18689.1 EQB61493.1 - 0.09 13.1 3.7 0.5 10.7 0.6 2.6 1 1 1 3 3 3 0 Primase X RVT_1 PF00078.27 EQB61494.1 - 0.045 13.3 0.6 0.08 12.4 0.5 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) v110 PF01639.17 EQB61497.1 - 0.15 11.9 2.9 1.6 8.7 0.3 3.1 2 0 0 2 2 2 0 Viral family 110 PhoLip_ATPase_C PF16212.5 EQB61498.1 - 2.4e-15 57.0 22.8 2.9e-15 56.7 22.8 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal BsuBI_PstI_RE PF06616.11 EQB61499.1 - 0.056 12.7 0.4 0.14 11.5 0.4 1.7 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain ESP PF16590.5 EQB61506.1 - 7.4 6.9 12.9 0.44 10.8 2.9 2.5 2 1 0 2 2 2 0 Exocrine gland-secreting peptide Phage_int_SAM_3 PF14659.6 EQB61507.1 - 0.052 13.8 0.6 0.052 13.8 0.6 2.1 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Glutaredoxin PF00462.24 EQB61508.1 - 4.6e-06 26.8 0.0 8.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Pro_isomerase PF00160.21 EQB61513.1 - 1e-44 152.6 2.0 1.2e-44 152.4 2.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.21 EQB61515.1 - 1.8e-37 128.9 34.9 5.5e-24 84.4 24.0 4.3 2 1 0 3 3 3 3 Myosin head (motor domain) AAA_16 PF13191.6 EQB61515.1 - 0.0046 17.4 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EQB61515.1 - 0.0078 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 EQB61515.1 - 0.028 14.4 0.0 0.028 14.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB61515.1 - 0.13 12.6 0.8 0.41 10.9 0.0 2.2 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 EQB61515.1 - 0.24 10.4 1.0 0.58 9.2 1.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Myosin_head PF00063.21 EQB61516.1 - 3.6e-15 55.3 24.8 1.1e-11 43.7 18.9 2.6 1 1 1 2 2 2 2 Myosin head (motor domain) Peptidase_S49_N PF08496.10 EQB61516.1 - 2.7 8.0 5.8 5.8 7.0 5.8 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SecY PF00344.20 EQB61517.1 - 2.8e-57 194.3 14.4 3.7e-57 193.9 14.4 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EQB61517.1 - 3.1e-17 62.1 0.3 8e-17 60.8 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF3925 PF13063.6 EQB61517.1 - 0.43 10.8 4.0 0.73 10.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) SecY PF00344.20 EQB61518.1 - 2.5e-57 194.4 14.4 3.3e-57 194.1 14.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EQB61518.1 - 2.9e-17 62.2 0.3 7.6e-17 60.9 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p DUF3925 PF13063.6 EQB61518.1 - 0.41 10.9 4.0 0.7 10.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) LRR_adjacent PF08191.11 EQB61519.1 - 0.11 12.8 0.4 0.3 11.3 0.4 1.8 1 0 0 1 1 1 0 LRR adjacent Methyltr_RsmB-F PF01189.17 EQB61520.1 - 3.2e-40 137.9 0.1 7.7e-40 136.7 0.1 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EQB61520.1 - 0.00024 21.3 0.1 0.00045 20.4 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EQB61520.1 - 0.00076 19.3 1.3 0.0012 18.6 0.3 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EQB61520.1 - 0.019 15.7 0.0 0.045 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Helicase_C PF00271.31 EQB61521.1 - 1.5e-12 47.8 0.1 1.5e-12 47.8 0.1 3.3 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HA2 PF04408.23 EQB61521.1 - 4.5e-07 30.1 0.0 9.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EQB61521.1 - 1.9e-06 28.2 0.0 5.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EQB61521.1 - 9.9e-05 22.4 1.5 0.00014 21.9 0.1 2.0 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EQB61521.1 - 0.00016 21.7 0.5 0.00016 21.7 0.5 3.5 3 1 1 4 4 4 1 AAA domain AAA_23 PF13476.6 EQB61521.1 - 0.00055 20.5 0.1 0.00055 20.5 0.1 3.4 4 0 0 4 4 4 1 AAA domain DEAD PF00270.29 EQB61521.1 - 0.00062 19.6 0.1 0.0019 18.0 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EQB61521.1 - 0.0071 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain Viral_helicase1 PF01443.18 EQB61521.1 - 0.011 15.5 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EQB61521.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 EQB61521.1 - 0.03 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EQB61521.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EQB61521.1 - 0.035 14.0 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 EQB61521.1 - 0.041 13.0 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ras PF00071.22 EQB61521.1 - 0.047 13.3 0.9 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Ras family Helicase_RecD PF05127.14 EQB61521.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_16 PF13191.6 EQB61521.1 - 0.071 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EQB61521.1 - 0.17 11.8 0.1 0.46 10.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 EQB61521.1 - 0.22 10.6 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APG6_N PF17675.1 EQB61525.1 - 0.014 15.9 10.0 0.014 15.9 10.0 3.1 1 1 1 3 3 3 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EQB61525.1 - 0.3 10.6 10.2 0.44 10.1 10.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 EQB61525.1 - 0.95 8.7 17.4 1.9 7.8 0.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EQB61525.1 - 1.5 8.0 19.4 1.8 7.7 8.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein Spc29 PF17082.5 EQB61525.1 - 2 8.2 22.6 7 6.4 6.3 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 Tho2 PF11262.8 EQB61525.1 - 5.9 6.0 22.4 1.5 8.0 5.2 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RL10P_insert PF17777.1 EQB61527.1 - 6.7e-12 45.2 0.0 9.1e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P SRP54 PF00448.22 EQB61528.1 - 1.3e-69 233.8 0.2 2.2e-69 233.0 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EQB61528.1 - 6.9e-25 87.6 4.8 8.1e-25 87.3 0.8 2.8 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 EQB61528.1 - 1.5e-11 44.4 0.4 4.2e-11 42.9 0.4 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EQB61528.1 - 1.7e-08 34.3 1.2 6.8e-06 25.8 1.7 3.0 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EQB61528.1 - 0.0024 16.9 0.4 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EQB61528.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 EQB61528.1 - 0.006 16.5 0.2 0.02 14.8 0.1 1.9 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 EQB61528.1 - 0.0066 16.5 0.0 0.019 15.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EQB61528.1 - 0.025 14.7 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EQB61528.1 - 0.045 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EQB61528.1 - 0.1 12.7 0.4 1.2 9.2 0.4 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.20 EQB61528.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MOZART1 PF12554.8 EQB61528.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Sec66 PF09802.9 EQB61529.1 - 0.0071 15.9 0.4 0.0087 15.7 0.4 1.3 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 SMC_N PF02463.19 EQB61530.1 - 2.8e-16 59.6 0.0 3.3e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EQB61530.1 - 2.2e-05 24.6 0.0 3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EQB61530.1 - 0.00047 20.1 0.0 0.00052 19.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RTT107_BRCT_6 PF16771.5 EQB61530.1 - 0.053 13.7 0.5 0.092 12.9 0.3 1.4 1 1 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Fe-ADH PF00465.19 EQB61530.1 - 0.22 10.3 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase SMC_N PF02463.19 EQB61531.1 - 8.5e-23 80.9 14.2 2.1e-22 79.6 13.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EQB61531.1 - 1.7e-14 54.8 12.9 1.7e-14 54.8 12.9 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EQB61531.1 - 1.3e-09 37.7 0.0 3.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EQB61531.1 - 3e-09 37.1 62.5 3e-09 37.1 62.5 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EQB61531.1 - 7.6e-06 26.0 1.9 7.6e-06 26.0 1.9 2.8 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 EQB61531.1 - 0.00021 21.6 0.1 0.00061 20.1 0.0 1.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain MukB PF04310.12 EQB61531.1 - 0.069 13.0 0.0 0.069 13.0 0.0 3.6 2 1 2 4 4 4 0 MukB N-terminal FtsK_SpoIIIE PF01580.18 EQB61531.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4349 PF14257.6 EQB61531.1 - 0.57 9.6 1.4 0.7 9.3 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Cyclin_C PF02984.19 EQB61533.1 - 1e-21 77.2 0.9 1.2e-21 77.0 0.3 1.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EQB61533.1 - 3.4e-09 36.5 2.3 5.2e-08 32.7 0.3 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain EF-hand_6 PF13405.6 EQB61533.1 - 0.31 11.1 1.6 4.1 7.6 0.2 2.9 3 0 0 3 3 3 0 EF-hand domain NIF3 PF01784.18 EQB61534.1 - 7.8e-24 84.6 0.3 7.7e-14 51.9 0.1 2.0 1 1 1 2 2 2 2 NIF3 (NGG1p interacting factor 3) V-ATPase_H_C PF11698.8 EQB61535.1 - 7e-26 90.6 1.9 8.3e-26 90.4 1.0 1.5 1 1 1 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 EQB61535.1 - 0.022 15.2 0.0 0.16 12.4 0.0 2.1 1 1 1 2 2 2 0 HEAT repeats zinc_ribbon_11 PF11682.8 EQB61535.1 - 0.045 13.8 0.2 0.071 13.1 0.2 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon MMR_HSR1 PF01926.23 EQB61536.1 - 1.7e-16 60.4 0.3 3.7e-15 56.0 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EQB61536.1 - 8.1e-08 31.9 0.6 0.0003 20.3 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EQB61536.1 - 2.3e-06 27.6 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EQB61536.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Pkinase PF00069.25 EQB61537.1 - 3.8e-66 223.2 0.2 4.4e-66 222.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61537.1 - 3.7e-39 134.6 0.0 4.6e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EQB61537.1 - 3e-08 33.3 0.1 6e-08 32.3 0.1 1.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EQB61537.1 - 5.2e-06 25.7 0.1 8.4e-05 21.7 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EQB61537.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EQB61537.1 - 0.029 13.7 0.1 0.11 11.9 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EQB61537.1 - 0.051 13.5 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PMM PF03332.13 EQB61538.1 - 1.1e-93 313.0 2.7 1.3e-93 312.8 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase ABC_tran PF00005.27 EQB61539.1 - 6.2e-29 101.3 0.0 1.1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EQB61539.1 - 6.2e-08 32.3 1.5 3.4e-06 26.7 1.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EQB61539.1 - 1.9e-06 27.9 0.2 0.00036 20.4 0.5 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EQB61539.1 - 0.00053 19.7 0.2 0.0014 18.3 0.1 1.8 1 1 1 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EQB61539.1 - 0.0025 17.8 0.1 0.0066 16.4 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 EQB61539.1 - 0.0049 16.0 2.0 0.028 13.5 0.3 2.2 1 1 1 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 EQB61539.1 - 0.0067 16.0 0.1 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_15 PF13175.6 EQB61539.1 - 0.0071 16.1 7.4 0.0071 16.1 7.4 2.6 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EQB61539.1 - 0.0072 16.4 0.1 0.024 14.7 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 EQB61539.1 - 0.0089 16.1 0.0 0.063 13.4 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_13 PF13166.6 EQB61539.1 - 0.016 13.9 6.8 0.035 12.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EQB61539.1 - 0.016 14.9 0.0 4.5 7.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 EQB61539.1 - 0.06 12.5 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 EQB61539.1 - 0.076 13.4 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EQB61539.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EQB61539.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EQB61539.1 - 0.15 11.8 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 EQB61539.1 - 0.18 11.9 0.0 1.6 8.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF1741 PF08427.10 EQB61540.1 - 0.021 14.5 4.5 0.046 13.4 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) Kinesin PF00225.23 EQB61541.1 - 7.5e-84 281.5 9.1 8.8e-84 281.3 9.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EQB61541.1 - 1.9e-19 70.1 2.3 1.9e-19 70.1 2.3 2.5 3 0 0 3 3 3 1 Microtubule binding Arf PF00025.21 EQB61542.1 - 2.3e-34 118.3 0.0 2.8e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EQB61542.1 - 2.8e-10 39.9 0.8 3.8e-06 26.3 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EQB61542.1 - 6.6e-10 38.8 0.2 2.5e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 EQB61542.1 - 9.9e-10 38.2 0.1 1.6e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EQB61542.1 - 1.4e-09 38.2 0.2 8.5e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EQB61542.1 - 9.3e-09 35.4 0.1 3.4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EQB61542.1 - 1.5e-07 31.1 2.8 1.1e-06 28.3 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EQB61542.1 - 6.6e-07 28.9 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EQB61542.1 - 0.0081 15.7 0.5 0.04 13.4 0.5 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 EQB61542.1 - 0.012 15.2 2.9 0.048 13.2 0.2 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 EQB61542.1 - 0.024 14.4 0.7 0.086 12.6 0.3 2.2 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Thymidylate_kin PF02223.17 EQB61542.1 - 0.058 13.1 0.1 0.094 12.4 0.1 1.4 1 1 0 1 1 1 0 Thymidylate kinase RsgA_GTPase PF03193.16 EQB61542.1 - 0.066 13.1 0.1 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SBD_N PF07005.11 EQB61542.1 - 0.067 12.9 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding N-terminal domain PduV-EutP PF10662.9 EQB61542.1 - 0.09 12.5 0.2 0.15 11.8 0.2 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EQB61542.1 - 0.13 11.9 0.1 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF5091 PF17012.5 EQB61543.1 - 2.5e-59 199.8 3.1 2.9e-59 199.6 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5091) DUF3347 PF11827.8 EQB61544.1 - 2.1 8.5 7.4 0.23 11.6 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Rad21_Rec8_N PF04825.13 EQB61545.1 - 5.7e-15 55.4 0.6 6.3e-15 55.3 0.6 1.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein LSM PF01423.22 EQB61546.1 - 2e-05 24.2 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain NAD_binding_5 PF07994.12 EQB61547.1 - 0.048 13.0 7.6 0.013 14.8 4.0 1.8 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase Seryl_tRNA_N PF02403.22 EQB61547.1 - 0.37 11.0 0.0 0.37 11.0 0.0 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Dus PF01207.17 EQB61548.1 - 3.3 6.7 7.0 2.4 7.2 5.9 1.4 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Proteasome PF00227.26 EQB61549.1 - 1.6e-21 76.7 0.0 2.1e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L22 PF00237.19 EQB61550.1 - 1.7e-27 95.6 0.1 2.5e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L40e PF01020.17 EQB61551.1 - 1.8e-09 37.3 7.2 1.8e-09 37.3 7.2 2.0 2 0 0 2 2 2 1 Ribosomal L40e family ubiquitin PF00240.23 EQB61551.1 - 0.00014 21.6 0.1 0.00047 19.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family ThiS-like PF14453.6 EQB61551.1 - 0.084 12.9 1.0 0.18 11.9 1.0 1.6 1 0 0 1 1 1 0 ThiS-like ubiquitin zinc_ribbon_10 PF10058.9 EQB61551.1 - 0.25 11.1 6.7 0.61 9.9 0.5 2.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein RhoGAP PF00620.27 EQB61552.1 - 9.7e-05 22.2 1.5 0.00017 21.5 1.5 1.4 1 0 0 1 1 1 1 RhoGAP domain BRAP2 PF07576.12 EQB61553.1 - 0.0013 18.9 1.8 0.0091 16.2 0.1 2.3 2 1 0 2 2 2 1 BRCA1-associated protein 2 RRM_1 PF00076.22 EQB61553.1 - 0.029 14.2 0.1 0.14 12.0 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1122 PF06557.11 EQB61553.1 - 0.031 13.7 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) ATP-synt_C PF00137.21 EQB61554.1 - 3e-06 27.5 7.5 3e-06 27.5 7.5 2.3 2 0 0 2 2 2 1 ATP synthase subunit C Pan3_PK PF18101.1 EQB61555.1 - 0.0043 17.0 9.7 1.4 8.9 0.7 3.2 1 1 3 4 4 4 4 Pan3 Pseudokinase domain DUF3215 PF11503.8 EQB61555.1 - 0.042 13.7 16.5 2.7 7.9 2.6 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3215) Ribosomal_S20p PF01649.18 EQB61555.1 - 0.097 13.3 6.5 95 3.7 6.5 3.2 1 1 0 1 1 1 0 Ribosomal protein S20 Rnk_N PF14760.6 EQB61555.1 - 0.25 11.8 1.0 3.8e+02 1.7 0.0 4.1 4 0 0 4 4 4 0 Rnk N-terminus DUF150_C PF17384.2 EQB61555.1 - 0.28 11.3 8.2 9.6 6.4 1.1 3.2 1 1 2 3 3 3 0 RimP C-terminal SH3 domain NES_C_h PF18208.1 EQB61555.1 - 0.97 9.7 9.8 8 6.8 2.4 2.7 1 1 1 2 2 2 0 Nicking enzyme C-terminal middle helical domain DUF4467 PF14729.6 EQB61555.1 - 8.3 6.8 17.0 3.7 8.0 4.8 2.6 1 1 1 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) DUF5021 PF16424.5 EQB61555.1 - 8.8 6.1 5.7 24 4.7 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5021) FCH PF00611.23 EQB61556.1 - 5.7 7.3 8.0 0.92 9.8 2.0 2.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain FtsJ PF01728.19 EQB61557.1 - 2.8e-51 174.1 0.0 4.9e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EQB61557.1 - 0.00024 21.0 18.7 0.00024 21.0 18.7 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 EQB61557.1 - 0.025 14.2 0.3 0.99 9.0 0.0 2.9 2 1 0 2 2 2 0 16S rRNA methyltransferase RsmB/F eIF-5_eIF-2B PF01873.17 EQB61558.1 - 7.6e-30 103.2 3.2 7.6e-30 103.2 3.2 2.2 2 0 0 2 2 2 1 Domain found in IF2B/IF5 WGG PF10273.9 EQB61558.1 - 0.028 15.1 0.2 0.07 13.8 0.2 1.7 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 PFK PF00365.20 EQB61559.1 - 1.5e-119 398.6 10.2 2.1e-98 329.2 5.7 3.3 2 1 0 2 2 2 2 Phosphofructokinase MCU PF04678.13 EQB61559.1 - 3 7.9 6.4 13 5.9 0.1 2.9 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2344 PF10105.9 EQB61561.1 - 0.0011 18.9 0.8 0.0013 18.6 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Lipoprotein_6 PF01441.19 EQB61561.1 - 0.02 14.9 1.5 0.02 14.9 1.5 2.0 1 1 1 2 2 2 0 Lipoprotein Nre_C PF04895.12 EQB61561.1 - 0.07 13.0 0.2 0.17 11.8 0.1 1.6 1 1 1 2 2 2 0 Archaeal Nre, C-terminal ApoO PF09769.9 EQB61561.1 - 0.2 11.6 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein O zf-CCCH PF00642.24 EQB61562.1 - 4.4e-10 39.2 36.6 0.00023 21.0 0.4 4.7 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EQB61562.1 - 4.8e-08 32.8 46.7 9.1e-05 22.4 4.0 5.7 5 1 0 5 5 5 3 Zinc finger domain Torus PF16131.5 EQB61562.1 - 1.4e-07 32.1 29.3 0.0026 18.4 2.5 4.2 1 1 3 4 4 4 4 Torus domain zf-CCCH_3 PF15663.5 EQB61562.1 - 2e-07 31.2 28.2 0.0031 17.7 5.5 4.0 1 1 3 4 4 4 4 Zinc-finger containing family zf-CCCH_2 PF14608.6 EQB61562.1 - 0.0016 18.9 44.4 0.0074 16.7 2.6 5.4 6 0 0 6 6 6 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EQB61562.1 - 0.051 13.4 2.2 0.051 13.4 2.2 5.1 4 2 0 4 4 4 0 CCCH-type zinc finger AWS PF17907.1 EQB61562.1 - 0.076 13.1 1.9 0.076 13.1 1.9 3.6 3 1 1 4 4 4 0 AWS domain DnaJ PF00226.31 EQB61563.1 - 0.0072 16.4 2.5 0.0074 16.4 0.1 2.4 3 0 0 3 3 3 1 DnaJ domain Uteroglobin PF01099.17 EQB61564.1 - 0.063 13.6 0.4 0.15 12.4 0.4 1.7 1 0 0 1 1 1 0 Uteroglobin family CX9C PF16860.5 EQB61564.1 - 0.095 12.7 2.0 0.27 11.3 2.0 1.8 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Actin PF00022.19 EQB61566.1 - 9.7e-142 472.3 0.0 4.2e-141 470.2 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EQB61566.1 - 0.0027 16.6 0.0 0.33 9.7 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein Forkhead PF00250.18 EQB61567.1 - 4.2e-33 113.5 0.4 6.1e-33 112.9 0.4 1.2 1 0 0 1 1 1 1 Forkhead domain Linker_histone PF00538.19 EQB61567.1 - 0.073 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 linker histone H1 and H5 family EMG1 PF03587.14 EQB61568.1 - 1.4e-16 60.7 0.3 1.9e-16 60.3 0.3 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF4621 PF15414.6 EQB61568.1 - 0.012 14.6 0.5 0.014 14.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) DUF1493 PF07377.12 EQB61568.1 - 0.54 10.7 3.6 3.5 8.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) BCL_N PF04714.13 EQB61570.1 - 0.18 11.9 0.0 0.94 9.6 0.0 2.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region WD40 PF00400.32 EQB61571.1 - 3.2e-08 34.1 9.1 0.0031 18.3 0.3 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Ribosomal_S3Ae PF01015.18 EQB61572.1 - 1.4e-61 207.6 10.4 1.7e-61 207.3 10.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Ret2_MD PF18528.1 EQB61572.1 - 0.016 15.6 0.3 0.046 14.1 0.3 1.7 1 0 0 1 1 1 0 RNA editing 3' terminal uridylyl transferase 2 middle domain GFA PF04828.14 EQB61573.1 - 0.017 15.4 1.4 0.043 14.2 0.6 2.1 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF4790 PF16037.5 EQB61574.1 - 0.09 13.2 1.4 3.3 8.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) ABC_tran PF00005.27 EQB61575.1 - 2.1e-16 60.7 0.0 4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EQB61575.1 - 0.0059 16.5 0.1 0.016 15.1 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase ATP-synt_ab PF00006.25 EQB61575.1 - 0.018 14.7 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 EQB61575.1 - 0.039 14.3 0.0 0.06 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EQB61575.1 - 6.9 6.0 7.1 4.9 6.5 2.3 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_polI_A14 PF08203.11 EQB61577.1 - 0.32 11.8 0.2 0.32 11.8 0.2 3.1 4 0 0 4 4 4 0 Yeast RNA polymerase I subunit RPA14 HATPase_c PF02518.26 EQB61578.1 - 7.4e-08 32.9 0.1 1.1e-07 32.3 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TOPRIM_C PF16898.5 EQB61579.1 - 4.9e-27 94.7 2.4 1.2e-26 93.5 2.4 1.7 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EQB61579.1 - 7e-22 77.7 2.9 1.4e-21 76.8 2.9 1.4 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 EQB61579.1 - 2.8e-08 33.9 0.4 2.5e-07 30.8 0.0 2.6 3 0 0 3 3 3 1 Toprim domain PDZ_3 PF17815.1 EQB61579.1 - 0.015 15.2 0.9 1.6 8.5 0.1 2.8 2 1 0 2 2 2 0 PDZ domain DNA_topoisoIV PF00521.20 EQB61580.1 - 1.1e-87 294.7 0.0 1.3e-87 294.5 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Acylphosphatase PF00708.18 EQB61580.1 - 0.099 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Acylphosphatase DNA_topoisoIV PF00521.20 EQB61581.1 - 2.7e-19 69.4 7.0 3.5e-19 69.0 7.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A MgtE PF01769.16 EQB61585.1 - 1.1e-14 54.8 28.5 4.6e-12 46.4 6.2 3.0 1 1 1 2 2 2 2 Divalent cation transporter XPG_N PF00752.17 EQB61585.1 - 0.13 12.7 0.8 1 9.8 0.0 2.4 2 0 0 2 2 2 0 XPG N-terminal domain Hist_deacetyl PF00850.19 EQB61586.1 - 2e-61 208.1 1.4 6.3e-59 199.9 0.0 2.5 2 1 1 3 3 3 2 Histone deacetylase domain PolyA_pol PF01743.20 EQB61587.1 - 8.9e-24 84.3 0.0 1.7e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EQB61587.1 - 0.014 15.2 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Gal4_dimer PF03902.13 EQB61587.1 - 0.31 11.2 1.6 36 4.6 0.1 3.6 3 0 0 3 3 3 0 Gal4-like dimerisation domain TPR_1 PF00515.28 EQB61588.1 - 3.3e-09 36.2 9.3 0.023 14.5 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EQB61588.1 - 4.2e-09 35.8 15.4 0.0084 16.1 0.0 6.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EQB61588.1 - 3.3e-07 30.7 0.4 0.00018 21.9 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EQB61588.1 - 1.2e-06 28.7 1.8 4 7.8 0.0 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EQB61588.1 - 2.9e-06 26.9 7.7 0.082 12.6 0.1 4.7 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 EQB61588.1 - 3.4e-06 27.0 1.9 0.0008 19.6 0.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EQB61588.1 - 0.00071 20.2 0.0 0.84 10.6 0.0 3.8 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EQB61588.1 - 0.00081 19.4 23.8 0.25 11.7 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EQB61588.1 - 0.0024 18.1 18.7 0.084 13.1 0.6 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EQB61588.1 - 0.0044 17.6 0.2 13 6.7 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Viral_cys_rich PF08008.12 EQB61588.1 - 0.032 14.3 1.4 0.032 14.3 1.4 2.5 2 0 0 2 2 2 0 Viral cysteine rich TPR_7 PF13176.6 EQB61588.1 - 0.046 13.7 0.1 12 6.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 EQB61589.1 - 1.4e-50 171.1 0.1 2.1e-39 135.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EQB61589.1 - 2.5e-10 40.8 0.3 0.00013 22.3 0.1 4.0 3 1 0 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 EQB61589.1 - 4.7e-10 39.1 0.0 1.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EQB61589.1 - 2e-08 34.5 0.1 5.4e-06 26.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EQB61589.1 - 4.8e-08 33.1 1.0 0.00024 21.1 0.2 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EQB61589.1 - 5.8e-08 33.1 0.0 0.029 14.8 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.6 EQB61589.1 - 1.3e-07 32.1 0.1 0.033 14.6 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain Mg_chelatase PF01078.21 EQB61589.1 - 2.2e-07 30.4 0.2 0.00063 19.2 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EQB61589.1 - 2.6e-07 30.5 0.0 0.0045 16.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EQB61589.1 - 3e-07 30.5 1.8 0.0032 17.5 0.5 3.3 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EQB61589.1 - 4.3e-07 30.5 0.0 0.0076 16.8 0.0 3.6 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EQB61589.1 - 3.3e-06 27.0 0.0 0.072 12.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 EQB61589.1 - 5.7e-06 26.2 0.7 0.084 12.6 0.3 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EQB61589.1 - 1.9e-05 24.1 0.3 0.026 13.9 0.0 3.3 3 0 0 3 3 3 1 KaiC AAA_3 PF07726.11 EQB61589.1 - 4e-05 23.5 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EQB61589.1 - 4.8e-05 23.3 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EQB61589.1 - 4.9e-05 22.9 0.1 0.082 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EQB61589.1 - 0.00025 20.7 2.1 0.27 10.8 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EQB61589.1 - 0.00027 21.1 0.0 0.086 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EQB61589.1 - 0.00043 20.8 0.3 0.035 14.6 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 EQB61589.1 - 0.00053 19.2 0.5 0.93 8.6 0.0 3.4 3 0 0 3 3 3 1 NB-ARC domain TIP49 PF06068.13 EQB61589.1 - 0.00091 18.5 0.0 0.21 10.8 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain PhoH PF02562.16 EQB61589.1 - 0.0026 17.2 0.1 1.9 7.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.17 EQB61589.1 - 0.0038 16.4 0.1 2.6 7.0 0.0 2.6 2 1 0 2 2 2 1 Parvovirus non-structural protein NS1 NACHT PF05729.12 EQB61589.1 - 0.0043 17.0 4.6 3.4 7.6 0.0 4.2 5 0 0 5 5 4 1 NACHT domain ResIII PF04851.15 EQB61589.1 - 0.0053 16.8 0.1 0.26 11.3 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 EQB61589.1 - 0.0087 15.8 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EQB61589.1 - 0.011 16.0 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EQB61589.1 - 0.013 15.9 0.0 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EQB61589.1 - 0.014 14.8 0.7 9.3 5.6 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein NTPase_1 PF03266.15 EQB61589.1 - 0.027 14.4 1.2 7.2 6.5 0.0 3.3 3 0 0 3 3 3 0 NTPase DUF2075 PF09848.9 EQB61589.1 - 0.03 13.6 0.3 0.73 9.0 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EQB61589.1 - 0.044 13.6 0.2 2.5 7.8 0.0 2.5 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EQB61589.1 - 0.078 13.2 0.0 20 5.4 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zot PF05707.12 EQB61589.1 - 0.095 12.3 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.6 EQB61589.1 - 0.098 13.1 0.0 32 4.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EQB61589.1 - 0.12 12.1 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EQB61589.1 - 0.16 11.7 0.3 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.22 EQB61589.1 - 0.25 10.9 3.9 4.8 6.8 0.1 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FCP1_C PF09309.10 EQB61590.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PGM_PMM_II PF02879.16 EQB61590.1 - 0.18 12.4 0.2 0.59 10.8 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF2207 PF09972.9 EQB61590.1 - 0.34 9.6 28.4 0.013 14.3 16.3 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ras PF00071.22 EQB61591.1 - 1.7e-50 170.8 2.5 2.1e-50 170.5 2.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB61591.1 - 4.9e-33 113.9 0.5 7.7e-33 113.3 0.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB61591.1 - 1.3e-18 67.0 1.0 1.8e-18 66.6 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EQB61591.1 - 1.5e-07 31.5 0.1 2.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EQB61591.1 - 1.2e-06 28.1 1.4 1.5e-06 27.7 1.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EQB61591.1 - 5.2e-06 26.0 0.5 6.5e-06 25.7 0.5 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EQB61591.1 - 1.4e-05 24.7 1.1 5.8e-05 22.7 1.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EQB61591.1 - 0.0011 18.8 1.0 0.013 15.4 0.0 2.2 1 1 1 2 2 2 1 RsgA GTPase Septin PF00735.18 EQB61591.1 - 0.0055 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EQB61591.1 - 0.0064 16.8 0.0 0.012 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EQB61591.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EQB61591.1 - 0.011 15.7 0.7 0.024 14.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EQB61591.1 - 0.016 15.6 0.0 0.11 12.9 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EQB61591.1 - 0.018 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EQB61591.1 - 0.018 15.0 0.0 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EQB61591.1 - 0.019 15.4 0.1 0.054 13.9 0.1 1.9 1 1 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EQB61591.1 - 0.044 12.7 0.1 0.76 8.6 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF3617 PF12276.8 EQB61591.1 - 0.072 13.4 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) ABC_tran PF00005.27 EQB61591.1 - 0.078 13.5 1.0 0.23 12.0 1.0 1.8 1 1 0 1 1 1 0 ABC transporter FtsZ_C PF12327.8 EQB61591.1 - 0.087 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Rhodanese PF00581.20 EQB61592.1 - 2.9e-14 53.5 0.1 1.2e-13 51.5 0.1 2.1 2 1 0 2 2 2 1 Rhodanese-like domain P53_C PF11619.8 EQB61593.1 - 0.22 11.6 1.6 2 8.6 1.6 2.2 1 1 0 1 1 1 0 Transcription factor P53 - C terminal domain Exo_endo_phos PF03372.23 EQB61594.1 - 4.8e-08 32.8 0.0 2.6e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EQB61594.1 - 0.00079 19.3 0.1 0.054 13.3 0.1 2.8 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Ribosomal_L36e PF01158.18 EQB61596.1 - 1.2e-16 60.7 7.9 1.3e-16 60.6 7.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e zf-C2H2_4 PF13894.6 EQB61597.1 - 0.035 15.0 16.3 0.49 11.4 2.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger MinE PF03776.14 EQB61597.1 - 0.044 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE zf-C2H2_8 PF15909.5 EQB61597.1 - 0.28 11.5 7.1 1.5 9.1 7.1 2.0 1 1 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 EQB61597.1 - 0.29 11.8 12.3 0.68 10.6 0.7 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 EQB61597.1 - 2.7 8.5 13.6 1.5 9.3 2.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EQB61597.1 - 6.2 7.4 15.7 3.9 8.1 1.7 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Cor1 PF04803.12 EQB61598.1 - 0.00018 21.7 2.0 0.0012 19.1 0.3 2.4 1 1 1 2 2 2 2 Cor1/Xlr/Xmr conserved region ENT PF03735.14 EQB61598.1 - 0.074 13.1 2.2 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 ENT domain Y_phosphatase PF00102.27 EQB61599.1 - 7.2e-15 55.2 0.4 1e-13 51.4 0.0 2.0 1 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 EQB61599.1 - 1.5e-07 31.3 0.2 2.4e-07 30.7 0.2 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EQB61599.1 - 0.024 14.6 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EQB61599.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4539 PF15072.6 EQB61600.1 - 1.5e-06 28.1 0.3 2.4e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) tRNA_anti_2 PF13742.6 EQB61600.1 - 0.0044 17.2 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rab5-bind PF09311.11 EQB61602.1 - 0.031 13.7 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Rabaptin-like protein CYTH PF01928.21 EQB61602.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 CYTH domain Tox-SGS PF15651.6 EQB61604.1 - 0.11 12.7 0.2 0.27 11.5 0.1 1.6 2 0 0 2 2 2 0 Salivary glad secreted protein domain toxin Aminotran_1_2 PF00155.21 EQB61605.1 - 1.7e-18 67.0 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hist_deacetyl PF00850.19 EQB61607.1 - 7.3e-64 216.2 1.1 2e-63 214.7 1.1 1.6 1 1 0 1 1 1 1 Histone deacetylase domain DUF3198 PF11433.8 EQB61608.1 - 0.12 12.3 0.7 0.12 12.3 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) FtsJ PF01728.19 EQB61609.1 - 4.8e-24 85.4 0.0 6.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Yos1 PF08571.10 EQB61610.1 - 5.2e-17 61.9 8.3 1.3e-14 54.2 8.3 2.0 1 1 0 1 1 1 1 Yos1-like DUF3671 PF12420.8 EQB61610.1 - 0.028 14.5 2.5 0.029 14.5 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF4957 PF16318.5 EQB61611.1 - 0.0031 17.5 1.8 0.0041 17.1 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4957) HTH_3 PF01381.22 EQB61611.1 - 0.11 12.6 0.5 0.2 11.7 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix Got1 PF04178.12 EQB61612.1 - 3.1e-20 72.7 15.3 3.3e-20 72.6 15.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family Rad52_Rad22 PF04098.15 EQB61613.1 - 1.2e-53 181.1 0.7 1.5e-53 180.8 0.7 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Protoglobin PF11563.8 EQB61613.1 - 0.091 12.6 0.1 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Protoglobin Sec61_beta PF03911.16 EQB61614.1 - 2.3e-05 24.3 1.0 2.3e-05 24.3 1.0 3.8 4 0 0 4 4 4 1 Sec61beta family UCH PF00443.29 EQB61614.1 - 0.0011 18.5 0.1 0.0011 18.5 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SpoIIIAH PF12685.7 EQB61614.1 - 0.0027 17.6 0.3 0.003 17.4 0.3 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1002 PF06207.11 EQB61616.1 - 0.13 11.8 5.3 0.032 13.8 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) YajC PF02699.15 EQB61617.1 - 0.12 12.3 0.8 0.28 11.1 0.8 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit LRR_4 PF12799.7 EQB61618.1 - 1.1e-09 38.3 35.2 0.00096 19.5 1.1 6.2 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB61618.1 - 5.1e-08 32.6 26.7 0.00017 21.3 6.2 5.0 4 1 2 6 6 6 5 Leucine rich repeat RsmF_methylt_CI PF17126.5 EQB61618.1 - 0.042 13.9 0.0 15 5.7 0.0 2.8 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain Dimer_Tnp_Tn5 PF02281.16 EQB61618.1 - 0.09 12.5 0.0 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain zf-C3HC4_3 PF13920.6 EQB61619.1 - 2.7e-09 36.8 7.7 2.7e-09 36.8 7.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EQB61619.1 - 7.4e-07 28.9 7.5 2.3e-06 27.4 7.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EQB61619.1 - 9.4e-07 28.6 9.5 2.3e-06 27.4 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB61619.1 - 9.7e-06 25.5 8.8 9.7e-06 25.5 8.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EQB61619.1 - 1.1e-05 25.1 10.8 1.1e-05 25.1 10.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EQB61619.1 - 1.7e-05 24.7 3.7 4.3e-05 23.4 1.7 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EQB61619.1 - 0.00072 19.8 8.7 0.00072 19.8 8.7 2.2 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 EQB61619.1 - 0.0015 18.8 4.4 0.0049 17.1 4.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF1272 PF06906.11 EQB61619.1 - 0.029 14.4 4.6 0.079 13.1 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn-C2H2_12 PF18112.1 EQB61619.1 - 0.038 14.5 0.6 0.13 12.8 0.6 1.9 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_4 PF15227.6 EQB61619.1 - 0.99 9.6 13.6 0.057 13.6 7.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EQB61619.1 - 3.1 7.6 7.7 10 6.0 4.0 3.3 2 1 1 3 3 3 0 RING-like zinc finger zf-RING_4 PF14570.6 EQB61619.1 - 5.3 6.9 11.5 1 9.2 7.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CorA PF01544.18 EQB61620.1 - 5.4e-15 55.5 2.9 7e-15 55.1 2.9 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Enolase_N PF03952.16 EQB61621.1 - 1.2e-35 122.6 0.0 2.3e-35 121.6 0.0 1.4 2 0 0 2 2 2 1 Enolase, N-terminal domain Enolase_C PF00113.22 EQB61621.1 - 5.1e-32 111.3 0.1 7.3e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Dynamin_N PF00350.23 EQB61622.1 - 1e-49 168.8 0.5 1.6e-49 168.2 0.5 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EQB61622.1 - 1.7e-17 63.6 0.3 3.7e-17 62.5 0.1 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EQB61622.1 - 1.2e-05 25.3 0.1 3.9e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EQB61622.1 - 0.0063 15.9 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family FeoB_N PF02421.18 EQB61622.1 - 0.06 12.9 0.7 6.6 6.2 0.4 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 EQB61622.1 - 0.067 12.5 4.3 1.8 7.8 0.3 2.8 2 1 0 3 3 3 0 AIG1 family Roc PF08477.13 EQB61622.1 - 0.085 13.1 0.4 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_M PF01031.20 EQB61623.1 - 3.6e-42 144.6 2.4 5.6e-42 143.9 2.4 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 EQB61623.1 - 6.9e-24 83.8 2.8 2.1e-23 82.3 2.8 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 EQB61624.1 - 3.2e-27 95.5 0.4 5.6e-27 94.7 0.4 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 EQB61624.1 - 1.4e-23 82.9 2.8 1.4e-23 82.9 2.8 1.8 3 0 0 3 3 3 1 Dynamin GTPase effector domain DcpS_C PF11969.8 EQB61625.1 - 2.8e-17 63.2 0.4 5.2e-17 62.4 0.4 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 EQB61625.1 - 8.7e-06 26.5 0.9 8.7e-06 26.5 0.9 2.1 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 EQB61625.1 - 0.1 13.4 0.2 0.29 11.9 0.2 1.8 1 1 0 1 1 1 0 HIT domain ubiquitin PF00240.23 EQB61626.1 - 3.7e-09 36.2 2.6 7.2e-09 35.3 2.6 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EQB61626.1 - 5.7e-05 22.9 0.3 0.00038 20.3 0.0 2.5 3 0 0 3 3 3 1 UBA/TS-N domain TBK1_ULD PF18396.1 EQB61626.1 - 0.0013 18.6 0.3 0.0032 17.4 0.3 1.7 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 EQB61626.1 - 0.0014 18.4 2.3 0.0014 18.4 2.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EQB61626.1 - 0.0053 17.2 1.7 0.0091 16.4 1.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain APG12 PF04110.13 EQB61626.1 - 0.011 16.2 2.7 0.034 14.6 0.3 2.6 2 2 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 Ubiquitin_4 PF18036.1 EQB61626.1 - 0.036 14.1 2.1 0.27 11.3 0.3 2.6 1 1 1 2 2 2 0 Ubiquitin-like domain DMA PF03474.14 EQB61626.1 - 0.042 13.5 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 DMRTA motif Tudor_RapA PF18337.1 EQB61626.1 - 0.16 12.2 0.2 0.45 10.7 0.2 1.8 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain RasGAP_C PF03836.15 EQB61627.1 - 1.2e-05 25.5 4.4 1.5e-05 25.2 4.4 1.2 1 0 0 1 1 1 1 RasGAP C-terminus Mg_trans_NIPA PF05653.14 EQB61629.1 - 4.9e-17 62.0 13.8 6.7e-11 41.8 5.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Nodulin_late PF07127.11 EQB61629.1 - 0.0004 20.7 0.7 0.0004 20.7 0.7 4.3 4 0 0 4 4 4 1 Late nodulin protein EmrE PF13536.6 EQB61629.1 - 0.029 13.9 2.0 4 6.9 0.2 2.4 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter EamA PF00892.20 EQB61629.1 - 0.7 10.1 24.9 1.2 9.4 6.5 2.8 2 1 0 3 3 3 0 EamA-like transporter family Saf_2TM PF18303.1 EQB61629.1 - 3.3 7.3 12.1 11 5.6 5.0 3.4 2 2 0 2 2 2 0 SAVED-fused 2TM effector domain Chs7 PF12271.8 EQB61631.1 - 3.6e-08 33.1 15.2 1.9e-07 30.7 9.5 2.0 1 1 1 2 2 2 2 Chitin synthase export chaperone TFIIE_alpha PF02002.17 EQB61633.1 - 1.5e-15 56.9 12.3 3.4e-15 55.8 12.3 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 EQB61633.1 - 4.2e-05 23.6 0.9 0.045 13.9 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain TFIIE-A_C PF11521.8 EQB61633.1 - 0.0023 18.2 4.8 0.0023 18.2 4.8 1.9 2 1 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Evr1_Alr PF04777.13 EQB61633.1 - 0.039 14.4 1.2 0.86 10.1 1.1 2.7 1 1 0 1 1 1 0 Erv1 / Alr family z-alpha PF02295.17 EQB61633.1 - 0.065 13.3 1.4 0.23 11.6 0.4 2.3 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain zf-C2H2 PF00096.26 EQB61633.1 - 0.067 13.7 1.1 1.1 9.9 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type C1_4 PF07975.12 EQB61633.1 - 0.099 12.9 3.6 0.25 11.6 3.6 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf_UBZ PF18439.1 EQB61633.1 - 0.1 12.2 2.0 1.5 8.5 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 EQB61633.1 - 1.1 9.3 4.0 14 5.8 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger ADK_lid PF05191.14 EQB61633.1 - 4.5 7.3 6.3 19 5.3 6.1 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid PSP1 PF04468.12 EQB61634.1 - 6.1e-12 45.7 0.3 1.2e-11 44.7 0.3 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF3828 PF12883.7 EQB61635.1 - 0.017 15.5 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) Fez1 PF06818.15 EQB61636.1 - 0.11 13.0 4.9 0.12 12.8 4.9 1.1 1 0 0 1 1 1 0 Fez1 TAF4 PF05236.14 EQB61637.1 - 4.2e-05 23.5 5.3 6.1e-05 22.9 5.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF4882 PF16223.5 EQB61637.1 - 0.0067 15.7 0.6 0.0088 15.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4882) SAS-6_N PF16531.5 EQB61637.1 - 1.1 9.9 6.6 0.61 10.7 4.0 1.8 2 1 0 2 2 2 0 Centriolar protein SAS N-terminal CH PF00307.31 EQB61639.1 - 1.6e-42 144.1 7.5 7.5e-23 80.8 0.7 2.7 2 1 1 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EQB61639.1 - 2.4e-12 46.5 0.1 8.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 EQB61639.1 - 0.011 15.8 9.9 0.23 11.6 0.2 3.4 2 1 1 3 3 3 0 CH-like domain in sperm protein PIN_6 PF17146.4 EQB61640.1 - 1.1e-12 48.3 0.0 2.1e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EQB61640.1 - 6.6e-12 45.4 1.2 6.6e-12 45.4 1.2 1.6 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like RELT PF12606.8 EQB61640.1 - 0.13 11.2 3.5 0.15 11.1 1.8 1.9 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 DZR PF12773.7 EQB61640.1 - 0.21 11.6 1.3 0.4 10.7 1.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon NOC3p PF07540.11 EQB61641.1 - 5.2e-07 30.0 1.7 5.2e-07 30.0 1.7 1.9 2 0 0 2 2 2 1 Nucleolar complex-associated protein DWNN PF08783.11 EQB61642.1 - 7.9e-22 77.3 1.7 1.6e-21 76.3 1.7 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EQB61642.1 - 7.5e-10 38.5 4.3 7.5e-10 38.5 4.3 3.0 3 0 0 3 3 3 1 Zinc knuckle zf-C3HC4_4 PF15227.6 EQB61642.1 - 3.7e-08 33.4 4.1 3.7e-08 33.4 4.1 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EQB61642.1 - 2.8e-07 30.4 9.8 6.6e-07 29.3 9.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EQB61642.1 - 0.0002 21.2 8.3 0.0002 21.2 8.3 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EQB61642.1 - 0.00023 20.9 7.9 0.00023 20.9 7.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EQB61642.1 - 0.00037 20.3 10.4 0.00037 20.3 10.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB61642.1 - 0.0013 18.7 13.3 0.0013 18.7 13.3 2.6 2 1 1 3 3 3 1 zinc-RING finger domain U-box PF04564.15 EQB61642.1 - 0.01 16.0 0.3 0.27 11.4 0.0 2.6 2 0 0 2 2 2 0 U-box domain zf-RING_2 PF13639.6 EQB61642.1 - 0.014 15.7 10.4 0.014 15.7 10.4 1.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_10 PF16685.5 EQB61642.1 - 0.45 10.7 13.2 0.046 13.8 8.3 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-FPG_IleRS PF06827.14 EQB61642.1 - 2.5 8.0 9.6 0.092 12.6 3.2 2.0 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-RRN7 PF11781.8 EQB61642.1 - 6.3 6.6 9.6 25 4.6 0.4 3.7 4 0 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 BIR PF00653.21 EQB61642.1 - 6.6 7.5 10.4 35 5.2 4.3 2.8 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Proteasome PF00227.26 EQB61643.1 - 1.8e-28 99.4 0.1 2.1e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Bac_transf PF02397.16 EQB61643.1 - 0.092 12.3 0.1 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial sugar transferase DNA_pol_B_exo1 PF03104.19 EQB61644.1 - 3.9e-43 147.9 0.6 4.7e-43 147.6 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EQB61644.1 - 1e-23 83.8 0.1 1.3e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 EQB61644.1 - 0.00011 21.3 0.4 0.00011 21.3 0.4 1.9 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EQB61644.1 - 0.0012 18.8 0.0 0.0068 16.4 0.0 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 EQB61644.1 - 0.0032 17.2 0.0 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease DNA_pol_B_exo2 PF10108.9 EQB61644.1 - 0.061 13.0 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_3 PF08408.10 EQB61644.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase family B viral insert DNA_pol_B PF00136.21 EQB61645.1 - 2.7e-52 178.0 4.2 3.9e-52 177.5 4.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EQB61645.1 - 1.4e-15 57.5 10.1 2.8e-15 56.5 10.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta INT_SG_DDX_CT_C PF15300.6 EQB61645.1 - 0.017 14.9 0.0 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DnaJ_CXXCXGXG PF00684.19 EQB61645.1 - 0.93 9.9 7.9 1.3 9.4 0.7 2.5 2 0 0 2 2 2 0 DnaJ central domain PTR2 PF00854.21 EQB61646.1 - 1.9e-68 231.2 22.7 8e-40 136.9 11.0 2.2 1 1 1 2 2 2 2 POT family Deltameth_res PF16020.5 EQB61646.1 - 0.48 10.3 8.8 0.46 10.4 3.6 3.3 3 0 0 3 3 3 0 Deltamethrin resistance Shikimate_dh_N PF08501.11 EQB61648.1 - 0.18 12.1 0.2 5.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain PCAF_N PF06466.11 EQB61649.1 - 0.068 12.7 0.2 0.075 12.6 0.2 1.0 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Endonuc_subdom PF09062.10 EQB61649.1 - 0.069 14.0 1.8 2.8 8.8 0.5 2.0 1 1 1 2 2 2 0 PI-PfuI Endonuclease subdomain RNA_pol_Rpb2_6 PF00562.28 EQB61650.1 - 2.3e-129 431.9 0.7 2.3e-129 431.9 0.7 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EQB61650.1 - 6.3e-55 185.8 0.1 9.3e-55 185.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EQB61650.1 - 1.1e-42 145.8 0.1 1.8e-42 145.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EQB61650.1 - 8.9e-32 109.4 0.1 2.9e-31 107.7 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EQB61650.1 - 8.5e-28 96.3 0.0 1.9e-27 95.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EQB61650.1 - 6.7e-24 84.0 2.3 9.9e-24 83.4 1.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EQB61650.1 - 6.8e-19 68.2 2.5 1.9e-18 66.8 2.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sod_Fe_C PF02777.18 EQB61651.1 - 3.1e-35 120.4 7.3 6e-35 119.5 1.8 2.7 2 1 1 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EQB61651.1 - 2.9e-12 46.9 2.9 2.9e-12 46.9 2.9 2.0 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, alpha-hairpin domain tRNA_deacylase PF04414.12 EQB61651.1 - 0.023 14.2 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase Erf4 PF10256.9 EQB61652.1 - 4e-07 30.1 2.5 1e-06 28.8 2.5 1.6 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SOAR PF16533.5 EQB61653.1 - 0.025 14.6 3.5 0.62 10.1 0.1 2.3 1 1 1 2 2 2 0 STIM1 Orai1-activating region PilJ PF13675.6 EQB61653.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4337 PF14235.6 EQB61653.1 - 0.088 12.9 1.7 0.11 12.5 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Aldedh PF00171.22 EQB61653.1 - 0.098 11.1 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ribosomal_L29 PF00831.23 EQB61653.1 - 0.57 10.2 6.4 0.15 12.1 2.6 2.0 2 0 0 2 2 2 0 Ribosomal L29 protein TcdB_N PF12918.7 EQB61653.1 - 1.5 9.1 0.0 1.5 9.1 0.0 4.2 4 1 1 5 5 5 0 TcdB toxin N-terminal helical domain ApoLp-III PF07464.11 EQB61653.1 - 3.1 7.9 9.0 0.51 10.4 3.4 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Ntox1 PF15500.6 EQB61654.1 - 0.073 13.4 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Coatomer_WDAD PF04053.14 EQB61656.1 - 3.1e-21 76.0 17.5 7e-20 71.5 17.5 2.2 1 1 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EQB61656.1 - 1.1e-20 73.5 6.4 6.8e-08 33.1 0.4 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB61656.1 - 0.00061 20.0 3.1 0.15 12.4 0.1 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 EQB61656.1 - 0.19 11.6 8.6 7.3 6.6 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EQB61656.1 - 0.84 10.0 8.4 16 6.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EQB61657.1 - 1.4e-22 80.3 14.2 1.7e-22 80.1 14.2 1.0 1 0 0 1 1 1 1 Coatomer WD associated region TPR_1 PF00515.28 EQB61657.1 - 0.011 15.6 8.0 3.7 7.5 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EQB61657.1 - 0.039 14.0 0.2 6.2 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EQB61657.1 - 0.079 13.2 8.5 7.7 7.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EQB61657.1 - 1.8 8.9 10.5 9 6.7 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 EQB61658.1 - 2e-08 34.7 0.3 0.21 12.5 0.0 4.3 3 1 1 4 4 4 3 WD domain, G-beta repeat Helicase_C_2 PF13307.6 EQB61661.1 - 1.5e-25 90.4 0.0 2.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain Maf1 PF09174.10 EQB61661.1 - 0.035 14.3 2.2 0.072 13.3 2.2 1.4 1 0 0 1 1 1 0 Maf1 regulator ResIII PF04851.15 EQB61662.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EQB61662.1 - 0.072 12.8 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase ANAPC4_WD40 PF12894.7 EQB61663.1 - 0.071 13.4 0.1 0.65 10.3 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_2 PF00152.20 EQB61664.1 - 1.2e-65 221.7 0.3 1.5e-65 221.3 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EQB61664.1 - 5.2e-09 36.0 1.7 1.1e-08 35.0 1.7 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EQB61664.1 - 0.033 13.7 0.1 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SusD-like PF12741.7 EQB61664.1 - 0.094 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein tRNA-synt_1b PF00579.25 EQB61665.1 - 2e-20 73.3 3.4 2.6e-15 56.5 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (W and Y) Pneumo_matrix PF03393.16 EQB61668.1 - 0.0012 18.1 1.2 0.042 13.1 0.4 2.3 1 1 1 2 2 2 2 Pneumovirus matrix protein Glutaredoxin PF00462.24 EQB61671.1 - 0.0092 16.2 0.1 0.044 14.0 0.1 2.2 1 1 1 2 2 2 1 Glutaredoxin Fibrillarin PF01269.17 EQB61672.1 - 2e-90 301.9 0.5 2.4e-90 301.6 0.5 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EQB61672.1 - 3e-05 23.8 0.0 3e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EQB61672.1 - 0.0061 16.3 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Got1 PF04178.12 EQB61673.1 - 9.1e-06 26.1 16.1 1.1e-05 25.9 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.8 EQB61673.1 - 1.8 8.9 10.7 1.8 8.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DAO PF01266.24 EQB61674.1 - 3.6e-38 132.1 0.0 4.7e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EQB61674.1 - 3.7e-25 88.2 0.0 1.3e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 EQB61674.1 - 2.1e-07 30.6 1.9 0.00028 20.4 1.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EQB61674.1 - 0.00061 18.6 0.6 0.0012 17.6 0.6 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EQB61674.1 - 0.0012 18.1 0.4 0.0047 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EQB61674.1 - 0.0015 17.7 0.7 0.018 14.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EQB61674.1 - 0.0016 17.6 1.6 0.0076 15.4 1.2 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EQB61674.1 - 0.0017 17.7 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EQB61674.1 - 0.0094 15.0 0.6 2.4 7.1 0.9 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EQB61674.1 - 0.032 13.5 2.4 0.042 13.1 1.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EQB61674.1 - 0.085 13.1 0.4 0.25 11.6 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EQB61674.1 - 0.22 12.1 0.6 0.72 10.5 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_18 PF13238.6 EQB61675.1 - 3.1e-19 69.8 0.0 4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EQB61675.1 - 3.4e-07 30.7 0.0 9.7e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EQB61675.1 - 2.2e-05 24.1 0.0 4.7e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EQB61675.1 - 0.00021 21.5 0.0 0.00084 19.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 EQB61675.1 - 0.00042 20.4 0.8 0.0028 17.7 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EQB61675.1 - 0.00056 20.3 0.1 0.0013 19.2 0.0 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EQB61675.1 - 0.00068 19.4 0.5 0.00093 19.0 0.5 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EQB61675.1 - 0.00099 19.5 0.0 0.0023 18.3 0.0 1.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 EQB61675.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.6 1 1 1 2 2 2 1 AAA domain SKI PF01202.22 EQB61675.1 - 0.0016 18.6 0.2 0.0027 17.9 0.2 1.5 1 1 0 1 1 1 1 Shikimate kinase TIP49 PF06068.13 EQB61675.1 - 0.0019 17.5 0.0 0.0024 17.1 0.0 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain dNK PF01712.19 EQB61675.1 - 0.0027 17.6 1.7 0.23 11.3 0.5 2.1 1 1 1 2 2 2 1 Deoxynucleoside kinase ATPase_2 PF01637.18 EQB61675.1 - 0.003 17.5 1.1 0.02 14.8 1.1 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EQB61675.1 - 0.0063 16.8 0.1 0.012 15.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain ADK PF00406.22 EQB61675.1 - 0.0088 16.2 0.2 0.08 13.0 0.2 2.6 1 1 0 1 1 1 1 Adenylate kinase TsaE PF02367.17 EQB61675.1 - 0.02 14.9 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EQB61675.1 - 0.025 14.5 0.3 0.1 12.5 0.1 2.0 2 1 1 3 3 2 0 NTPase Viral_helicase1 PF01443.18 EQB61675.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EQB61675.1 - 0.028 13.7 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thymidylate_kin PF02223.17 EQB61675.1 - 0.036 13.7 0.2 3.2 7.4 0.1 2.4 2 1 0 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.12 EQB61675.1 - 0.037 13.3 0.0 0.081 12.2 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EQB61675.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 EQB61675.1 - 0.051 13.3 0.1 0.41 10.3 0.0 2.0 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 EQB61675.1 - 0.057 12.8 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 KaiC DKNYY PF13644.6 EQB61675.1 - 0.061 14.1 5.8 0.087 13.6 5.8 1.3 1 0 0 1 1 1 0 DKNYY family IstB_IS21 PF01695.17 EQB61675.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EQB61675.1 - 0.14 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EQB61675.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 EQB61675.1 - 0.21 11.8 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AMP-binding PF00501.28 EQB61677.1 - 2.2e-82 276.9 0.0 2.7e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UQ_con PF00179.26 EQB61680.1 - 9.3e-50 167.9 0.1 1.1e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EQB61680.1 - 1.6e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EQB61680.1 - 8.9e-06 26.0 0.1 1.1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 RWD domain zf-HC5HC2H_2 PF13832.6 EQB61681.1 - 4.9e-20 71.7 5.7 4.9e-20 71.7 5.7 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.6 EQB61681.1 - 5.3e-13 48.3 1.0 5.3e-13 48.3 1.0 2.4 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 EQB61681.1 - 4.2e-08 33.3 1.8 4.2e-08 33.3 1.8 3.5 3 1 1 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 EQB61681.1 - 1.9e-06 27.6 4.9 1.9e-06 27.6 4.9 3.5 3 1 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EQB61681.1 - 0.00025 20.7 7.0 0.00025 20.7 7.0 2.5 1 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EQB61681.1 - 0.00091 19.1 2.8 0.00091 19.1 2.8 3.4 2 1 0 3 3 3 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 EQB61681.1 - 0.015 15.1 0.9 0.015 15.1 0.9 3.7 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_60s PF00428.19 EQB61683.1 - 0.0027 18.2 5.3 0.0065 17.0 5.3 1.6 1 1 0 1 1 1 1 60s Acidic ribosomal protein DUF5096 PF17019.5 EQB61685.1 - 1.1e-30 106.9 18.0 1.3e-30 106.6 18.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5096) DUF2778 PF10908.8 EQB61685.1 - 0.045 14.0 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) DUF3591 PF12157.8 EQB61686.1 - 5.3e-31 107.8 0.2 5.3e-31 107.8 0.2 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 EQB61686.1 - 3e-19 68.9 0.4 1e-18 67.1 0.4 2.0 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 EQB61686.1 - 6.8e-06 25.8 2.1 1.3e-05 25.0 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EQB61686.1 - 0.024 14.7 1.1 0.052 13.6 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle SBDS PF01172.18 EQB61688.1 - 0.0089 16.1 4.2 0.0093 16.0 0.4 2.9 2 1 1 3 3 3 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein AAA PF00004.29 EQB61689.1 - 9.4e-43 145.8 0.0 1.9e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EQB61689.1 - 7.2e-18 64.3 0.0 1.7e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EQB61689.1 - 9.8e-14 50.9 0.1 2.4e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EQB61689.1 - 2.9e-07 30.5 0.1 9.3e-07 28.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EQB61689.1 - 6.9e-06 26.3 0.0 2.1e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EQB61689.1 - 1.2e-05 25.1 0.0 3.6e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EQB61689.1 - 1.5e-05 25.5 0.1 0.016 15.6 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EQB61689.1 - 0.00081 19.7 0.5 0.19 12.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 EQB61689.1 - 0.0012 18.4 0.2 0.1 12.0 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.13 EQB61689.1 - 0.0085 15.3 0.0 0.017 14.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EQB61689.1 - 0.0095 15.3 0.1 0.022 14.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EQB61689.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EQB61689.1 - 0.017 14.7 0.1 0.035 13.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EQB61689.1 - 0.022 14.5 0.2 0.069 12.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EQB61689.1 - 0.027 14.2 0.2 0.26 11.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 EQB61689.1 - 0.033 13.6 0.1 6.3 6.1 0.0 2.3 1 1 1 2 2 2 0 Isopentenyl transferase IstB_IS21 PF01695.17 EQB61689.1 - 0.034 13.9 0.2 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EQB61689.1 - 0.034 14.5 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EQB61689.1 - 0.035 14.1 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EQB61689.1 - 0.092 11.9 0.0 0.24 10.5 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 EQB61689.1 - 0.13 11.6 0.1 0.76 9.1 0.0 2.0 2 0 0 2 2 2 0 KaiC Acyltransferase PF01553.21 EQB61690.1 - 1.9e-20 72.9 0.0 2.7e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase ORC2 PF04084.14 EQB61692.1 - 0.0092 14.9 1.0 0.017 14.1 0.3 1.7 1 1 1 2 2 2 1 Origin recognition complex subunit 2 AAA PF00004.29 EQB61695.1 - 1.1e-42 145.5 0.0 2.7e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EQB61695.1 - 9.3e-18 63.9 0.0 2.1e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EQB61695.1 - 1.2e-13 50.6 0.1 3e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EQB61695.1 - 3.7e-07 30.2 0.5 1.3e-06 28.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EQB61695.1 - 8e-06 26.1 0.0 2.8e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EQB61695.1 - 1.5e-05 24.8 0.0 4.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EQB61695.1 - 2e-05 25.1 0.1 0.021 15.2 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EQB61695.1 - 0.001 19.3 0.5 0.26 11.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 EQB61695.1 - 0.0017 17.8 0.2 0.12 11.8 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein Mg_chelatase PF01078.21 EQB61695.1 - 0.0096 15.3 0.1 0.026 13.9 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EQB61695.1 - 0.011 16.0 0.1 0.03 14.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EQB61695.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EQB61695.1 - 0.016 14.7 0.0 0.043 13.3 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EQB61695.1 - 0.026 14.2 0.2 0.089 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EQB61695.1 - 0.03 14.0 0.2 0.32 10.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EQB61695.1 - 0.037 14.4 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EQB61695.1 - 0.04 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EQB61695.1 - 0.042 13.6 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein IPT PF01745.16 EQB61695.1 - 0.042 13.2 0.1 8.1 5.8 0.0 2.4 1 1 1 2 2 2 0 Isopentenyl transferase Parvo_NS1 PF01057.17 EQB61695.1 - 0.18 10.9 0.8 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF948 PF06103.11 EQB61695.1 - 0.91 9.8 4.3 1.2 9.4 1.5 2.6 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.27 EQB61695.1 - 4.3 7.8 6.0 18 5.9 0.0 3.4 3 2 1 4 4 4 0 ABC transporter DSHCT PF08148.12 EQB61697.1 - 1.8e-41 141.6 0.2 3.3e-41 140.7 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EQB61697.1 - 0.0063 16.5 0.3 0.0063 16.5 0.3 2.6 1 1 0 2 2 2 1 rRNA-processing arch domain PB1-F2 PF11986.8 EQB61697.1 - 0.046 13.9 0.1 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Influenza A Proapoptotic protein DEAD PF00270.29 EQB61698.1 - 6e-18 65.2 0.0 1.1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EQB61698.1 - 1.7e-08 34.7 0.4 3.1e-08 33.8 0.4 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EQB61698.1 - 0.0025 18.1 0.1 0.014 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EQB61698.1 - 0.02 14.8 0.5 0.02 14.8 0.5 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EQB61698.1 - 0.1 12.6 1.3 0.37 10.8 0.5 2.3 2 1 0 2 2 2 0 AAA domain KH_6 PF15985.5 EQB61699.1 - 2.6e-11 43.7 0.0 6.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 EQB61699.1 - 7.6e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 EQB61699.1 - 0.021 15.4 0.1 0.039 14.6 0.1 1.5 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Reovirus_M2 PF05993.12 EQB61699.1 - 0.13 10.3 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Beta-Casp PF10996.8 EQB61700.1 - 1.5e-26 92.9 0.0 2.4e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EQB61700.1 - 4.7e-16 58.5 0.0 9.5e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain TMEM215 PF15746.5 EQB61700.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 TMEM215 family Lactamase_B PF00753.27 EQB61701.1 - 4.2e-11 43.2 0.0 5.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EQB61701.1 - 1.5e-06 27.8 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EQB61701.1 - 0.00016 21.2 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EQB61701.1 - 0.0064 16.4 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EQB61701.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 1 0 1 1 1 0 Putative beta-lactamase-like family MS_channel PF00924.18 EQB61702.1 - 1e-12 48.0 0.7 1.4e-12 47.6 0.7 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel PIG-F PF06699.11 EQB61702.1 - 0.018 15.2 0.5 0.036 14.2 0.2 1.6 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F Aldo_ket_red PF00248.21 EQB61703.1 - 9.1e-35 120.3 0.0 8.6e-34 117.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4093 PF13331.6 EQB61703.1 - 0.12 12.8 0.0 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) Ribosomal_S13 PF00416.22 EQB61704.1 - 2.6e-30 105.5 1.1 3e-30 105.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EQB61704.1 - 0.002 17.0 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) RTC PF01137.21 EQB61706.1 - 4.2e-23 81.7 0.0 5.4e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EQB61706.1 - 6.4e-09 36.3 0.0 9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SLAM PF06214.11 EQB61706.1 - 0.0031 17.5 1.2 0.0053 16.8 0.2 1.8 2 0 0 2 2 2 1 Signaling lymphocytic activation molecule (SLAM) protein Ribul_P_3_epim PF00834.19 EQB61707.1 - 2.9e-37 128.0 1.4 3.3e-37 127.8 1.4 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Evr1_Alr PF04777.13 EQB61710.1 - 1.3e-27 96.1 0.3 1.9e-27 95.7 0.3 1.2 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC4 PF18775.1 EQB61710.1 - 0.032 14.4 0.2 0.07 13.3 0.2 1.6 1 0 0 1 1 1 0 APOBEC4 DUF3792 PF12670.7 EQB61710.1 - 0.094 12.9 0.5 0.17 12.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Ribosomal_L19e PF01280.20 EQB61711.1 - 1.2e-49 168.1 11.9 1.7e-49 167.6 11.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L19e SHOCT PF09851.9 EQB61711.1 - 0.00052 19.7 0.1 0.0022 17.7 0.1 2.1 1 0 0 1 1 1 1 Short C-terminal domain FPRL1_inhibitor PF16104.5 EQB61711.1 - 0.57 10.4 5.3 0.24 11.6 1.9 1.9 1 1 1 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein PGBA_C PF15437.6 EQB61711.1 - 1.4 9.3 13.6 2.5 8.5 0.3 2.8 1 1 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Cpn60_TCP1 PF00118.24 EQB61712.1 - 6.2e-138 460.5 11.9 7.2e-138 460.3 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 EQB61712.1 - 0.11 12.6 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Resolvase, N terminal domain Guanylate_cyc PF00211.20 EQB61713.1 - 2.2e-06 27.4 0.3 3.4e-06 26.8 0.3 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Thiolase_N PF00108.23 EQB61714.1 - 2.3e-59 200.9 0.0 3.5e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EQB61714.1 - 7.3e-45 151.6 0.1 1.6e-44 150.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EQB61714.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain CRCB PF02537.15 EQB61714.1 - 0.07 13.4 0.2 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) E3_binding PF02817.17 EQB61714.1 - 0.18 12.1 0.2 0.9 9.9 0.0 2.3 2 0 0 2 2 2 0 e3 binding domain Cation_ATPase PF13246.6 EQB61715.1 - 0.00016 21.6 0.5 0.00024 21.1 0.5 1.5 1 1 0 1 1 1 1 Cation transport ATPase (P-type) DUF3922 PF13059.6 EQB61715.1 - 0.057 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) DASH_Dam1 PF08653.10 EQB61715.1 - 0.11 12.3 1.2 11 6.0 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 tRNA-synt_2d PF01409.20 EQB61716.1 - 1.1e-87 293.6 0.0 1.5e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 EQB61716.1 - 4.5e-11 42.6 0.0 9.5e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD3 PF18553.1 EQB61716.1 - 2.5e-10 40.5 0.2 1.4e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 EQB61716.1 - 0.0011 18.1 1.3 0.0065 15.6 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EQB61716.1 - 0.0029 17.6 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sec6 PF06046.13 EQB61717.1 - 2.5e-67 227.6 15.6 2.9e-67 227.4 8.6 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec6 SRP_TPR_like PF17004.5 EQB61717.1 - 0.0035 17.4 0.5 0.0078 16.2 0.5 1.6 1 0 0 1 1 1 1 Putative TPR-like repeat Erv26 PF04148.13 EQB61718.1 - 8.1e-14 51.9 12.4 2.2e-12 47.2 12.4 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 SHQ1 PF04925.15 EQB61718.1 - 0.096 12.2 5.4 2.5 7.7 1.4 2.0 1 1 1 2 2 2 0 SHQ1 protein CTP_transf_1 PF01148.20 EQB61719.1 - 1.5e-53 182.3 20.6 1.8e-53 182.0 20.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family FAM72 PF14976.6 EQB61719.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 FAM72 protein Proteasome PF00227.26 EQB61720.1 - 4.5e-17 62.2 0.0 5.3e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit zf-DBF PF07535.12 EQB61721.1 - 1.1e-16 60.7 4.8 1.7e-16 60.0 3.9 1.9 1 1 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.10 EQB61721.1 - 0.0045 17.2 3.8 0.009 16.2 0.0 2.9 3 1 1 4 4 4 1 Dfp1/Him1, central region S4 PF01479.25 EQB61722.1 - 9e-07 28.5 0.0 2.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EQB61722.1 - 1.9e-05 25.5 0.1 2.5e-05 25.1 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TPR_1 PF00515.28 EQB61723.1 - 2.6e-12 46.0 3.0 3.5e-07 29.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EQB61723.1 - 1.9e-09 36.9 1.1 0.0042 17.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EQB61723.1 - 1.2e-05 25.1 6.1 0.18 12.1 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EQB61723.1 - 0.00015 21.3 0.2 0.036 13.7 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 EQB61723.1 - 0.00031 20.9 0.4 0.93 9.8 0.1 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EQB61723.1 - 0.0036 17.2 0.6 4 7.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EQB61723.1 - 0.011 16.1 0.1 11 6.6 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat CLZ PF16526.5 EQB61723.1 - 0.027 14.8 2.0 0.2 12.0 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1359 PF07097.11 EQB61723.1 - 0.046 14.0 1.1 0.082 13.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) Ubiq-assoc PF09145.10 EQB61723.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.9 4 0 0 4 4 4 0 Ubiquitin-associated XhlA PF10779.9 EQB61723.1 - 4 7.7 8.6 1.1 9.6 2.0 2.6 2 1 0 2 2 2 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 EQB61723.1 - 4.5 7.7 6.7 0.87 10.1 0.3 2.6 3 1 0 3 3 3 0 Snapin/Pallidin HhH-GPD PF00730.25 EQB61724.1 - 1.3e-09 38.5 0.0 7.6e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2400 PF09674.10 EQB61724.1 - 0.12 12.4 2.3 1.4 8.9 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) Bac_RepA_C PF18008.1 EQB61724.1 - 0.3 11.5 6.9 0.054 13.8 2.2 2.2 2 1 0 2 2 2 0 Replication initiator protein A C-terminal domain EndIII_4Fe-2S PF10576.9 EQB61724.1 - 3.4 8.1 6.6 4.2 7.8 5.5 1.8 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Aa_trans PF01490.18 EQB61725.1 - 2.1e-61 207.9 42.4 2.8e-61 207.4 42.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EQB61725.1 - 1.2e-06 27.8 20.3 1.2e-06 27.8 20.3 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family VioE PF18234.1 EQB61725.1 - 0.075 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE Hrs_helical PF12210.8 EQB61726.1 - 0.002 18.6 0.5 0.0029 18.1 0.5 1.2 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Velvet PF11754.8 EQB61727.1 - 0.0025 17.8 3.2 0.0025 17.8 3.2 1.9 1 1 1 2 2 2 1 Velvet factor Mit_KHE1 PF10173.9 EQB61727.1 - 7.9 6.5 10.2 0.73 9.9 4.5 2.1 2 1 0 2 2 2 0 Mitochondrial K+-H+ exchange-related CdiA_C_tRNase PF18664.1 EQB61728.1 - 0.053 13.7 0.4 0.053 13.7 0.4 3.7 3 3 2 5 5 5 0 CdiA C-terminal tRNase domain N_Asn_amidohyd PF14736.6 EQB61728.1 - 0.23 10.6 3.9 6.4 5.9 0.0 3.3 1 1 2 3 3 3 0 Protein N-terminal asparagine amidohydrolase Aa_trans PF01490.18 EQB61729.1 - 1.5e-09 37.1 28.5 5e-09 35.4 28.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5412 PF17428.2 EQB61729.1 - 9.1 6.2 8.2 8.4 6.3 1.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5412) PUF PF00806.19 EQB61730.1 - 1.3e-17 62.3 0.7 2.6e-06 26.8 0.1 3.6 3 0 0 3 3 3 3 Pumilio-family RNA binding repeat TatD_DNase PF01026.21 EQB61731.1 - 7.9e-39 133.6 0.0 1.5e-24 86.8 0.0 2.0 1 1 1 2 2 2 2 TatD related DNase DUF1192 PF06698.11 EQB61732.1 - 0.0012 18.9 11.4 0.037 14.1 1.2 4.3 4 0 0 4 4 4 2 Protein of unknown function (DUF1192) DUF3209 PF11483.8 EQB61732.1 - 0.14 12.6 5.9 0.14 12.6 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) T3SSipB PF16535.5 EQB61732.1 - 1.5 9.3 24.6 0.19 12.2 3.3 3.1 1 1 2 3 3 3 0 Type III cell invasion protein SipB Mod_r PF07200.13 EQB61732.1 - 1.5 8.9 46.2 0.26 11.4 5.7 3.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Baculo_PEP_C PF04513.12 EQB61732.1 - 1.8 8.6 8.4 2.4 8.2 4.8 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EQB61732.1 - 2 7.7 27.5 0.32 10.3 21.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EQB61732.1 - 4 7.8 8.6 2.4 8.4 2.0 3.3 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) APG17 PF04108.12 EQB61732.1 - 6 5.9 34.1 0.62 9.1 20.5 3.0 1 1 1 2 2 2 0 Autophagy protein Apg17 AAA_13 PF13166.6 EQB61732.1 - 6.3 5.3 44.0 0.13 10.9 31.3 2.2 1 1 1 2 2 2 0 AAA domain COG5 PF10392.9 EQB61732.1 - 8.2 6.6 25.9 0.072 13.3 5.8 3.9 3 2 1 4 4 4 0 Golgi transport complex subunit 5 ApoO PF09769.9 EQB61732.1 - 9.7 6.2 10.9 1.6 8.7 0.7 3.3 2 2 1 3 3 3 0 Apolipoprotein O Septin PF00735.18 EQB61733.1 - 1.4e-69 234.5 2.2 1.8e-69 234.2 2.2 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EQB61733.1 - 1.7e-06 28.1 0.1 3.1e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EQB61733.1 - 0.00026 20.5 0.1 0.00066 19.2 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EQB61733.1 - 0.01 15.9 1.2 6.1 6.9 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Hit1_C PF18268.1 EQB61733.1 - 0.015 15.5 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Hit1 C-terminal GTP_EFTU PF00009.27 EQB61733.1 - 0.14 11.7 0.1 15 5.1 0.1 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RabGAP-TBC PF00566.18 EQB61734.1 - 5.4e-27 94.9 6.5 9.3e-27 94.1 6.4 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Scm3 PF10384.9 EQB61734.1 - 0.28 11.0 3.3 2.1 8.1 1.0 2.5 2 0 0 2 2 2 0 Centromere protein Scm3 Myb_DNA-binding PF00249.31 EQB61735.1 - 1.4e-33 114.8 3.1 8.2e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EQB61735.1 - 3.7e-25 88.0 8.2 1.6e-17 63.4 0.7 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1722 PF08349.11 EQB61735.1 - 0.023 15.0 1.2 0.24 11.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF3752 PF12572.8 EQB61735.1 - 0.033 14.7 0.6 2.7 8.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) Sigma70_r4_2 PF08281.12 EQB61735.1 - 0.13 12.0 0.0 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DDE_Tnp_1_7 PF13843.6 EQB61736.1 - 7.3e-72 242.6 1.7 8.8e-72 242.3 1.7 1.1 1 0 0 1 1 1 1 Transposase IS4 Rx_N PF18052.1 EQB61737.1 - 0.069 13.4 0.0 13 6.2 0.0 2.3 2 0 0 2 2 2 0 Rx N-terminal domain CNOT1_HEAT PF16418.5 EQB61737.1 - 0.085 12.9 4.5 0.24 11.4 0.6 2.5 1 1 1 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Stap_Strp_toxin PF01123.20 EQB61738.1 - 7.4 7.5 20.8 1.2 10.0 3.2 3.1 1 1 2 3 3 3 0 Staphylococcal/Streptococcal toxin, OB-fold domain RPN7 PF10602.9 EQB61739.1 - 9e-27 93.9 0.3 1.4e-26 93.3 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EQB61739.1 - 9.4e-12 45.4 1.3 2.1e-11 44.3 1.3 1.6 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 EQB61739.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RNase_PH PF01138.21 EQB61740.1 - 8.2e-08 32.8 0.5 5.5e-07 30.2 0.5 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Curto_V2 PF07325.11 EQB61740.1 - 0.15 11.9 3.2 1.7 8.6 0.3 2.1 2 0 0 2 2 2 0 Curtovirus V2 protein RT_RNaseH PF17917.1 EQB61742.1 - 7e-20 71.3 0.1 6.8e-19 68.1 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EQB61742.1 - 5.1e-18 65.0 0.0 1.7e-17 63.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EQB61742.1 - 2e-10 40.6 2.6 5.2e-10 39.3 2.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 EQB61742.1 - 0.0082 16.8 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EQB61742.1 - 0.01 16.4 0.0 0.042 14.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 EQB61742.1 - 0.17 12.1 2.7 0.14 12.4 0.3 2.2 2 0 0 2 2 2 0 H2C2 zinc finger Sin3a_C PF16879.5 EQB61743.1 - 1.8e-07 31.1 6.4 3.9e-07 30.1 3.6 2.3 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EQB61743.1 - 0.0005 20.1 1.7 0.0013 18.8 0.1 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor Pkinase PF00069.25 EQB61744.1 - 5.6e-44 150.5 0.3 6.9e-44 150.2 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61744.1 - 3.7e-21 75.6 0.0 5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EQB61744.1 - 0.00058 19.5 0.1 0.0035 17.0 0.1 1.9 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EQB61744.1 - 0.00081 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EQB61744.1 - 0.0056 16.3 0.4 0.0056 16.3 0.4 1.7 2 1 0 2 2 2 1 Choline/ethanolamine kinase FTA2 PF13095.6 EQB61744.1 - 0.0088 15.7 0.2 2 8.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EQB61744.1 - 0.0088 15.4 1.9 0.036 13.4 0.1 2.4 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family NMT PF01233.19 EQB61745.1 - 5.7e-37 127.0 0.2 5.7e-37 127.0 0.2 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EQB61745.1 - 2.8e-27 95.6 4.4 5.8e-27 94.6 4.4 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 EQB61745.1 - 3.5e-07 30.5 0.1 4.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EQB61745.1 - 0.0043 17.5 2.2 0.064 13.7 0.6 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EQB61745.1 - 0.014 15.3 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mu-like_Com PF10122.9 EQB61745.1 - 0.22 11.0 0.0 0.44 10.0 0.0 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com TRAPPC-Trs85 PF12739.7 EQB61746.1 - 0.19 10.7 4.2 0.28 10.1 4.2 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit AAA PF00004.29 EQB61747.1 - 3.1e-42 144.1 0.1 8e-42 142.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EQB61747.1 - 7.6e-10 38.4 0.3 1.6e-09 37.4 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EQB61747.1 - 6.8e-06 26.1 0.1 4.3e-05 23.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB61747.1 - 9.6e-06 25.9 0.1 0.0043 17.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EQB61747.1 - 1.1e-05 25.9 0.2 0.00037 20.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EQB61747.1 - 6.2e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EQB61747.1 - 0.00011 21.9 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EQB61747.1 - 0.00023 21.3 0.0 0.00085 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EQB61747.1 - 0.00033 19.9 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EQB61747.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EQB61747.1 - 0.0025 18.0 0.0 0.0045 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EQB61747.1 - 0.0057 16.2 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EQB61747.1 - 0.008 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EQB61747.1 - 0.0083 15.5 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EQB61747.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EQB61747.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.7 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 EQB61747.1 - 0.012 15.6 0.0 0.39 10.6 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EQB61747.1 - 0.014 15.1 0.1 0.05 13.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EQB61747.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EQB61747.1 - 0.038 13.7 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EQB61747.1 - 0.049 13.5 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 EQB61747.1 - 0.057 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EQB61747.1 - 0.079 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 EQB61747.1 - 0.085 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 EQB61747.1 - 0.098 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EQB61747.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EQB61747.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EQB61747.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EQB61747.1 - 0.2 11.4 0.0 0.52 10.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain TFIIF_beta PF02270.15 EQB61749.1 - 5e-15 55.4 0.0 8.4e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EQB61749.1 - 5e-06 27.3 0.4 9.3e-06 26.4 0.4 1.7 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Gly_acyl_tr_C PF08444.10 EQB61750.1 - 0.79 10.0 2.6 25 5.2 0.5 2.6 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region KH_8 PF17903.1 EQB61752.1 - 4.8e-35 119.5 1.9 1.6e-34 117.8 1.9 1.9 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EQB61752.1 - 0.47 10.3 4.1 0.19 11.6 0.7 2.0 2 1 0 2 2 2 0 KH domain HATPase_c PF02518.26 EQB61754.1 - 7.4e-08 32.9 0.1 1.1e-07 32.3 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_gyraseB PF00204.25 EQB61755.1 - 4.8e-22 78.3 3.0 8.2e-22 77.5 3.0 1.3 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 EQB61755.1 - 9.1e-07 29.1 0.4 4.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Toprim domain PDZ_3 PF17815.1 EQB61755.1 - 0.022 14.6 0.8 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 PDZ domain DUF3846 PF12957.7 EQB61755.1 - 0.096 13.0 0.0 0.91 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) DNA_gyraseB PF00204.25 EQB61756.1 - 3.9e-22 78.5 3.0 6.6e-22 77.8 3.0 1.3 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 EQB61756.1 - 7.1e-07 29.4 0.4 3.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain PDZ_3 PF17815.1 EQB61756.1 - 0.056 13.3 2.5 2.5 8.0 0.0 2.5 3 0 0 3 3 3 0 PDZ domain DUF3846 PF12957.7 EQB61756.1 - 0.077 13.3 0.0 0.8 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) DNA_topoisoIV PF00521.20 EQB61757.1 - 1.7e-52 178.8 0.0 1.9e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_topoisoIV PF00521.20 EQB61758.1 - 1e-09 37.8 0.1 1.2e-09 37.6 0.1 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Acylphosphatase PF00708.18 EQB61758.1 - 0.011 16.2 0.0 0.037 14.4 0.0 1.7 2 0 0 2 2 2 0 Acylphosphatase DNA_topoisoIV PF00521.20 EQB61759.1 - 2.7e-19 69.4 7.0 3.5e-19 69.0 7.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A LRR_8 PF13855.6 EQB61761.1 - 1.8e-09 37.2 39.2 0.00021 21.0 8.5 4.9 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EQB61761.1 - 9.1e-07 29.1 51.3 0.0094 16.4 6.4 6.1 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) Spore_YpjB PF09577.10 EQB61762.1 - 0.036 13.9 1.5 0.041 13.7 1.5 1.0 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Cullin_Nedd8 PF10557.9 EQB61764.1 - 0.0066 16.5 2.9 0.0066 16.5 2.9 1.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Cullin PF00888.22 EQB61765.1 - 0.00089 18.0 35.7 0.0025 16.5 35.7 1.6 1 1 0 1 1 1 1 Cullin family RRM_1 PF00076.22 EQB61769.1 - 0.0012 18.6 0.1 0.0022 17.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 EQB61769.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif MBOAT PF03062.19 EQB61770.1 - 0.00011 21.7 1.3 0.00016 21.2 1.3 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Tmemb_55A PF09788.9 EQB61770.1 - 0.13 11.3 1.3 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Transmembrane protein 55A Symplekin_C PF12295.8 EQB61771.1 - 0.0098 16.0 0.1 0.0098 16.0 0.1 2.9 4 0 0 4 4 4 1 Symplekin tight junction protein C terminal Arrestin_N PF00339.29 EQB61772.1 - 0.00016 21.7 1.8 0.00034 20.7 0.2 2.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EQB61772.1 - 0.0025 18.3 2.9 0.057 13.9 0.4 2.9 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain TACI-CRD2 PF09305.10 EQB61772.1 - 0.12 12.4 0.3 13 5.9 0.1 2.5 2 0 0 2 2 2 0 TACI, cysteine-rich domain Proteasome PF00227.26 EQB61773.1 - 1.4e-44 151.9 0.0 1.7e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EQB61773.1 - 6.7e-11 41.7 0.0 1.7e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature LRR_4 PF12799.7 EQB61776.1 - 1.9e-10 40.8 16.0 3.4e-06 27.3 5.0 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB61776.1 - 6.4e-09 35.4 4.4 6.4e-09 35.4 4.4 3.7 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 EQB61776.1 - 0.051 14.1 17.8 1.7 9.5 0.4 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EQB61776.1 - 0.36 11.0 6.7 0.71 10.1 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat tRNA-synt_2b PF00587.25 EQB61777.1 - 2.2e-08 34.3 0.1 4.2e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EQB61777.1 - 0.073 12.5 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) HGTP_anticodon PF03129.20 EQB61778.1 - 8.9e-17 61.0 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Fib_alpha PF08702.10 EQB61778.1 - 0.2 11.9 1.7 0.29 11.3 0.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RNA_pol_Rpb1_5 PF04998.17 EQB61779.1 - 0.087 12.2 4.2 0.15 11.5 4.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Interfer-bind PF09294.10 EQB61779.1 - 0.28 11.5 4.1 1.3 9.4 0.6 2.6 2 0 0 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Pro_isomerase PF00160.21 EQB61781.1 - 6.2e-38 130.6 1.8 8.5e-38 130.1 1.8 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M17 PF00883.21 EQB61782.1 - 3.2e-110 368.3 0.2 3.6e-110 368.1 0.2 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF220 PF02713.14 EQB61783.1 - 0.064 13.4 0.6 0.11 12.6 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF220 NPV_P10 PF05531.12 EQB61784.1 - 0.46 11.0 3.8 5 7.7 0.5 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Methyltransf_11 PF08241.12 EQB61786.1 - 7.2e-17 61.8 0.0 1.8e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EQB61786.1 - 2.4e-15 56.7 0.1 3.3e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EQB61786.1 - 7.1e-14 52.3 0.0 1.6e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EQB61786.1 - 4.9e-10 39.4 0.3 1.2e-09 38.1 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EQB61786.1 - 4.3e-07 30.6 0.1 1.2e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EQB61786.1 - 7e-05 22.3 0.1 0.00015 21.2 0.1 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TB2_DP1_HVA22 PF03134.19 EQB61787.1 - 0.009 15.9 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Spore_Cse60 PF10957.8 EQB61787.1 - 0.021 14.9 0.8 0.046 13.8 0.1 1.9 2 0 0 2 2 2 0 Sporulation protein Cse60 RSD-2 PF07547.13 EQB61788.1 - 0.22 12.1 2.1 2 8.9 0.1 2.6 2 1 0 2 2 2 0 RSD-2 N-terminal domain Ribo_biogen_C PF04034.13 EQB61789.1 - 4.8e-48 162.1 0.2 5.8e-48 161.8 0.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EQB61789.1 - 3.8e-10 39.4 0.6 8.6e-10 38.3 0.6 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CBP_BcsN PF17038.5 EQB61791.1 - 0.039 13.3 0.1 0.065 12.6 0.1 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN LIAS_N PF16881.5 EQB61791.1 - 0.097 13.1 1.4 0.13 12.7 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family AAA_14 PF13173.6 EQB61791.1 - 1.6 8.8 9.5 0.37 10.8 5.2 2.0 1 1 1 2 2 2 0 AAA domain DUF536 PF04394.14 EQB61792.1 - 0.86 9.5 15.8 1.5e+02 2.3 0.1 7.5 8 0 0 8 8 8 0 Protein of unknown function, DUF536 Remorin_C PF03763.13 EQB61792.1 - 9.3 6.2 17.1 1.3 9.0 1.5 3.4 1 1 3 4 4 4 0 Remorin, C-terminal region BIR PF00653.21 EQB61793.1 - 3.4e-15 56.5 2.0 3.4e-15 56.5 2.0 2.0 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 EQB61793.1 - 0.0014 18.7 3.4 0.0014 18.7 3.4 2.1 2 1 1 3 3 3 1 C3HC zinc finger-like Ribosomal_S6e PF01092.19 EQB61794.1 - 4.6e-46 155.8 0.3 7.7e-46 155.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e PseudoU_synth_2 PF00849.22 EQB61795.1 - 3.3e-25 89.0 0.0 6.3e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.18 EQB61795.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) GWT1 PF06423.12 EQB61796.1 - 1.5e-05 25.2 14.0 1.5e-05 25.2 14.0 2.8 2 2 0 2 2 2 1 GWT1 RhoGAP PF00620.27 EQB61797.1 - 1.9e-20 73.2 2.0 1.1e-19 70.8 0.2 2.0 2 0 0 2 2 2 1 RhoGAP domain PXB PF12828.7 EQB61797.1 - 0.082 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 PX-associated Lactamase_B_2 PF12706.7 EQB61798.1 - 2.9e-14 53.1 0.0 5.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EQB61798.1 - 3.4e-05 23.4 0.1 0.00028 20.5 0.1 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_6 PF16661.5 EQB61798.1 - 9.1e-05 22.0 1.4 0.00013 21.5 0.5 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EQB61798.1 - 0.0002 21.4 0.0 0.00032 20.8 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EQB61798.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_transf_41 PF13844.6 EQB61799.1 - 0.19 10.2 4.5 0.2 10.1 4.5 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 Swi5 PF07061.11 EQB61799.1 - 0.49 10.5 8.0 1.7 8.8 8.0 1.9 1 1 0 1 1 1 0 Swi5 SMP_LBD PF17047.5 EQB61801.1 - 0.0044 16.5 0.3 0.02 14.3 0.2 1.8 1 1 1 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain FidL_like PF15941.5 EQB61801.1 - 0.054 14.0 1.9 0.18 12.2 0.2 2.4 2 1 1 3 3 3 0 FidL-like putative membrane protein AAA_6 PF12774.7 EQB61803.1 - 4.3e-19 68.7 2.6 1.1e-17 64.1 0.2 3.9 3 1 1 4 4 4 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EQB61803.1 - 2.7e-10 40.1 2.7 0.0043 16.6 0.2 4.5 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_5 PF07728.14 EQB61803.1 - 2.3e-08 34.1 0.0 0.079 12.9 0.0 4.8 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB61803.1 - 2.3e-05 24.7 0.0 0.63 10.3 0.0 4.7 5 0 0 5 5 5 2 AAA domain TniB PF05621.11 EQB61803.1 - 8.6e-05 22.0 0.1 0.52 9.7 0.0 3.5 3 0 0 3 3 3 2 Bacterial TniB protein AAA_16 PF13191.6 EQB61803.1 - 0.00027 21.4 0.0 0.81 10.0 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 EQB61803.1 - 0.00097 19.3 0.2 5.7 7.2 0.0 4.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EQB61803.1 - 0.0015 18.5 0.0 5.3 7.1 0.0 3.6 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EQB61803.1 - 0.0067 16.8 0.3 1.8 9.0 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Arm_3 PF16186.5 EQB61804.1 - 0.13 11.8 6.4 0.53 9.9 1.1 2.7 2 1 0 2 2 2 0 Atypical Arm repeat DUF5319 PF17252.2 EQB61804.1 - 0.17 12.1 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5319) LRR_8 PF13855.6 EQB61805.1 - 3.4e-40 135.6 87.1 1.2e-09 37.8 2.7 7.3 3 1 6 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 EQB61805.1 - 4.2e-27 93.7 83.4 1.8e-07 31.4 2.1 8.8 2 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB61805.1 - 9.9e-07 28.4 37.9 0.0078 15.7 3.1 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EQB61805.1 - 0.00025 21.2 64.8 0.87 10.4 0.1 12.3 12 1 0 12 12 12 4 Leucine Rich Repeat LRR_6 PF13516.6 EQB61805.1 - 0.0031 17.4 65.4 2.4 8.4 0.4 12.2 13 0 0 13 13 13 7 Leucine Rich repeat CREPT PF16566.5 EQB61805.1 - 0.16 12.1 1.7 6.1 7.0 0.0 3.5 4 1 1 5 5 5 0 Cell-cycle alteration and expression-elevated protein in tumour rve PF00665.26 EQB61806.1 - 0.011 15.9 1.5 24 5.1 0.0 4.1 3 1 1 4 4 4 0 Integrase core domain PhoLip_ATPase_C PF16212.5 EQB61807.1 - 3.3e-22 79.5 7.8 4.6e-22 79.0 7.8 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EQB61807.1 - 1.1e-11 45.4 0.0 1.8e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EQB61807.1 - 0.00025 20.9 2.2 0.00071 19.4 0.3 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L5e PF17144.4 EQB61809.1 - 7.5e-66 221.1 1.5 1.2e-65 220.5 1.5 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EQB61809.1 - 8.1e-27 94.0 10.6 8.1e-27 94.0 10.6 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Nop14 PF04147.12 EQB61810.1 - 0.075 11.2 0.1 0.078 11.2 0.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sec63 PF02889.16 EQB61811.1 - 0.00011 21.5 8.9 0.00034 19.9 8.9 1.9 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EQB61811.1 - 0.0011 19.1 4.5 0.0011 19.1 4.5 2.4 2 0 0 2 2 2 1 DnaJ domain Proteasome PF00227.26 EQB61812.1 - 3e-18 66.0 0.1 7.2e-18 64.7 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit NSP11 PF06471.12 EQB61812.1 - 0.008 14.7 0.2 0.0096 14.4 0.2 1.1 1 0 0 1 1 1 1 NSP11 RVT_1 PF00078.27 EQB61813.1 - 4.6e-06 26.3 2.9 0.0003 20.4 0.3 2.7 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EQB61813.1 - 0.00046 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 EQB61813.1 - 0.024 14.9 0.1 0.078 13.3 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 EQB61813.1 - 0.033 14.0 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EQB61813.1 - 0.044 14.3 0.0 0.097 13.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH_2 PF17919.1 EQB61813.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 EQB61813.1 - 0.6 10.0 0.0 0.6 10.0 0.0 2.4 3 0 0 3 3 3 0 Reverse transcriptase thumb domain CENP-L PF13092.6 EQB61815.1 - 0.0026 18.0 0.2 0.0098 16.1 0.2 2.1 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 LAGLIDADG_2 PF03161.13 EQB61815.1 - 2.1 8.3 8.0 0.21 11.6 1.9 2.3 2 2 1 3 3 3 0 LAGLIDADG DNA endonuclease family AAA PF00004.29 EQB61816.1 - 8.8e-13 48.8 0.1 1.8e-12 47.8 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EQB61816.1 - 4.1e-12 46.3 0.0 9.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 EQB61816.1 - 9.6e-08 32.2 0.1 4.2e-07 30.1 0.1 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EQB61816.1 - 0.00015 21.5 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EQB61816.1 - 0.011 16.1 1.0 0.035 14.5 0.1 2.3 2 2 1 3 3 3 0 RNA helicase DUF815 PF05673.13 EQB61816.1 - 0.016 14.4 0.1 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EQB61816.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EQB61816.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EQB61816.1 - 0.036 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EQB61816.1 - 0.054 13.5 0.0 0.25 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PTCB-BRCT PF12738.7 EQB61816.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain AAA_22 PF13401.6 EQB61816.1 - 0.11 12.7 0.1 17 5.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.13 EQB61817.1 - 5.7e-88 295.5 2.7 1.6e-87 293.9 2.7 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EQB61817.1 - 2.4e-05 24.4 1.5 7.6e-05 22.8 1.5 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EQB61817.1 - 4.6e-05 23.9 0.0 9.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EQB61817.1 - 0.0001 22.3 3.8 0.00011 22.2 0.2 2.4 1 1 2 3 3 3 1 Rad17 P-loop domain AAA_18 PF13238.6 EQB61817.1 - 0.0001 22.8 0.2 0.00075 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EQB61817.1 - 0.00012 21.3 0.0 0.00035 19.7 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EQB61817.1 - 0.00013 22.3 0.4 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EQB61817.1 - 0.00015 22.3 7.1 0.00037 21.1 7.1 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EQB61817.1 - 0.0003 20.6 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EQB61817.1 - 0.00091 19.7 0.1 0.0019 18.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EQB61817.1 - 0.0011 19.0 0.2 0.0036 17.3 0.2 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EQB61817.1 - 0.003 17.5 1.7 0.0038 17.2 0.3 1.9 2 1 0 2 2 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EQB61817.1 - 0.0031 18.0 0.1 0.0085 16.6 0.1 1.7 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 EQB61817.1 - 0.0051 17.2 0.2 0.12 12.8 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_5 PF07728.14 EQB61817.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EQB61817.1 - 0.0069 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EQB61817.1 - 0.0092 15.7 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 EQB61817.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EQB61817.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IPT PF01745.16 EQB61817.1 - 0.029 13.7 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase AAA_2 PF07724.14 EQB61817.1 - 0.032 14.3 0.7 0.061 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) ResIII PF04851.15 EQB61817.1 - 0.04 13.9 0.1 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 EQB61817.1 - 0.041 13.5 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EQB61817.1 - 0.041 13.3 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EQB61817.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 EQB61817.1 - 0.13 12.7 0.2 2.6 8.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EQB61817.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EQB61817.1 - 0.51 10.7 1.7 1.6 9.1 1.7 2.3 1 1 0 1 1 1 0 AAA domain NMD3 PF04981.13 EQB61818.1 - 6.3e-60 202.6 4.5 6.3e-60 202.6 4.5 1.5 2 0 0 2 2 2 1 NMD3 family NOT2_3_5 PF04153.18 EQB61819.1 - 4.1e-16 59.3 2.8 5.5e-16 58.9 2.8 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family HECT PF00632.25 EQB61820.1 - 9.7e-54 182.9 8.9 1.6e-53 182.2 8.9 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) 4HBT_3 PF13622.6 EQB61821.1 - 1.2e-20 74.8 0.0 1.1e-19 71.6 0.0 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EQB61821.1 - 4.2e-12 46.1 0.0 9.8e-07 28.7 0.0 2.8 2 1 0 2 2 2 2 Acyl-CoA thioesterase Homeobox_KN PF05920.11 EQB61822.1 - 1.9e-15 56.5 0.3 4e-15 55.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EQB61822.1 - 4.8e-06 26.3 0.1 9.7e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Homeodomain RHD_DNA_bind PF00554.22 EQB61822.1 - 0.0017 18.4 0.8 0.0021 18.0 0.8 1.2 1 0 0 1 1 1 1 Rel homology DNA-binding domain TSNAXIP1_N PF15739.5 EQB61823.1 - 0.028 14.8 1.5 0.035 14.5 1.5 1.0 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Homeobox_KN PF05920.11 EQB61824.1 - 6.2e-19 67.6 0.4 9.3e-19 67.1 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EQB61824.1 - 4.1e-07 29.8 0.1 6.9e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 EQB61824.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3069 PF11269.8 EQB61825.1 - 0.08 13.2 1.7 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) GLTSCR1 PF15249.6 EQB61828.1 - 7.5e-07 29.5 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein DUF3533 PF12051.8 EQB61828.1 - 0.15 10.9 2.0 0.21 10.4 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Ribosomal_S25 PF03297.15 EQB61831.1 - 1.4e-19 70.2 5.5 2e-19 69.7 5.5 1.2 1 0 0 1 1 1 1 S25 ribosomal protein DUF2711 PF10924.8 EQB61831.1 - 0.0038 16.9 1.0 0.12 12.0 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2711) PRC2_HTH_1 PF18118.1 EQB61832.1 - 0.73 10.7 4.2 1.6 9.6 4.2 1.5 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain DUF5071 PF16804.5 EQB61833.1 - 9.3e-05 22.7 1.5 0.00019 21.7 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5071) BCHF PF07284.11 EQB61835.1 - 0.036 14.1 1.9 0.3 11.1 0.5 2.3 1 1 1 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) DEAD PF00270.29 EQB61836.1 - 1e-20 74.2 0.0 1.4e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EQB61836.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EQB61837.1 - 2.9e-34 117.7 0.7 4.2e-34 117.2 0.2 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEPN_MAE_28990 PF18737.1 EQB61837.1 - 0.005 16.8 1.6 0.0077 16.2 1.3 1.4 1 1 1 2 2 2 1 MAE_28990/MAE_18760-like HEPN ERCC3_RAD25_C PF16203.5 EQB61837.1 - 0.0075 15.5 0.2 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EQB61837.1 - 0.013 15.3 0.0 0.069 12.9 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2313 PF10076.9 EQB61837.1 - 0.04 13.8 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) Radical_SAM_C PF16199.5 EQB61838.1 - 3.1e-32 110.4 0.0 6.5e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EQB61838.1 - 3.3e-20 73.1 2.2 1.2e-18 68.0 0.1 3.0 2 1 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EQB61838.1 - 4.7e-07 30.1 0.1 1.9e-06 28.1 0.1 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EQB61838.1 - 1.7e-05 24.7 0.9 0.0001 22.2 0.5 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EQB61838.1 - 0.0056 17.1 0.3 0.012 16.0 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 EQB61839.1 - 6.5e-12 45.8 7.7 0.0003 21.5 0.9 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB61839.1 - 1.9e-07 31.3 0.4 1.1 9.7 0.0 5.7 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Trm112p PF03966.16 EQB61840.1 - 2.2e-06 28.1 0.1 3e-06 27.7 0.1 1.5 1 1 0 1 1 1 1 Trm112p-like protein Ribosomal_L14 PF00238.19 EQB61841.1 - 1.8e-08 34.5 0.0 2.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribonuc_red_lgN PF00317.21 EQB61842.1 - 2.8e-18 65.7 0.2 1e-17 63.9 0.0 1.9 2 1 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain BTB PF00651.31 EQB61842.1 - 0.06 13.6 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 BTB/POZ domain LRR_8 PF13855.6 EQB61843.1 - 3.2e-09 36.4 4.3 4.3e-09 36.0 0.8 2.8 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EQB61843.1 - 0.00043 20.6 3.1 0.00043 20.6 3.1 3.1 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB61844.1 - 1.3e-23 82.5 37.4 1.2e-06 28.2 0.3 6.4 1 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EQB61844.1 - 6.8e-21 74.0 49.1 8.6e-06 26.0 1.2 8.0 3 1 7 10 10 10 9 Leucine Rich repeats (2 copies) Pentapeptide_4 PF13599.6 EQB61844.1 - 0.39 10.9 4.9 3.1 8.0 0.1 3.8 4 1 0 4 4 4 0 Pentapeptide repeats (9 copies) LRR_6 PF13516.6 EQB61844.1 - 4.2 7.7 0.0 4.2 7.7 0.0 7.4 12 0 0 12 12 12 0 Leucine Rich repeat Mnd1 PF03962.15 EQB61845.1 - 1.2e-22 80.0 1.4 1.2e-22 80.0 1.4 2.4 2 1 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EQB61845.1 - 4.5e-13 49.1 5.4 4.5e-13 49.1 5.4 2.8 1 1 0 2 2 2 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 EQB61845.1 - 0.0038 17.6 3.3 0.018 15.4 0.6 2.4 2 1 1 3 3 3 1 Penicillinase repressor RNase_HII PF01351.18 EQB61845.1 - 0.045 13.6 6.9 0.071 12.9 6.9 1.3 1 0 0 1 1 1 0 Ribonuclease HII FUR PF01475.19 EQB61845.1 - 0.12 12.5 8.8 0.052 13.7 4.4 2.4 1 1 1 2 2 2 0 Ferric uptake regulator family Cob_adeno_trans PF01923.18 EQB61845.1 - 0.47 10.6 3.5 11 6.2 0.0 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase CTP_transf_like PF01467.26 EQB61846.1 - 5.7e-27 94.7 0.1 1.7e-26 93.2 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like tRNA-synt_1e PF01406.19 EQB61846.1 - 0.079 12.3 3.4 5.5 6.2 0.0 2.6 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain MinE PF03776.14 EQB61846.1 - 0.13 12.3 1.8 0.31 11.1 1.8 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE DUF5639 PF18690.1 EQB61846.1 - 0.22 11.7 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5639) SAS4 PF15460.6 EQB61846.1 - 0.22 11.6 2.3 0.32 11.1 0.7 2.1 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Lectin_leg-like PF03388.13 EQB61849.1 - 0.18 11.1 0.2 0.25 10.7 0.2 1.1 1 0 0 1 1 1 0 Legume-like lectin family Arc_C PF18162.1 EQB61850.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Arc C-lobe Arc_C PF18162.1 EQB61851.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Arc C-lobe Syja_N PF02383.18 EQB61852.1 - 9e-18 64.6 0.1 1.1e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain GATA PF00320.27 EQB61854.1 - 1.2e-15 56.8 2.9 2e-15 56.1 2.9 1.4 1 0 0 1 1 1 1 GATA zinc finger Ribosomal_L37ae PF01780.19 EQB61854.1 - 0.55 10.4 4.2 2.6 8.2 0.2 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF1216 PF06746.11 EQB61857.1 - 0.0051 16.8 5.0 0.0051 16.8 5.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1216) Ribosomal_L9_N PF01281.19 EQB61858.1 - 0.038 13.6 0.2 0.069 12.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain PCNA_N PF00705.18 EQB61860.1 - 1.6e-23 82.8 0.5 4e-23 81.5 0.5 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EQB61860.1 - 3e-17 63.0 2.0 4.8e-17 62.3 0.6 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EQB61860.1 - 1.6e-08 34.3 0.4 4.1e-08 33.0 0.1 1.7 1 1 0 2 2 2 1 Rad9 Rad1 PF02144.16 EQB61860.1 - 0.0012 18.0 1.5 0.014 14.5 0.1 2.1 1 1 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rep_fac-A_3 PF08661.11 EQB61860.1 - 0.0093 16.3 0.2 0.083 13.2 0.2 2.1 2 0 0 2 2 2 1 Replication factor A protein 3 TruB_N PF01509.18 EQB61861.1 - 1.2e-22 80.8 0.4 1e-18 68.1 0.4 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.12 EQB61861.1 - 1.1e-20 73.4 0.3 1.1e-20 73.4 0.3 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EQB61861.1 - 2e-19 69.5 0.0 4.2e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EQB61861.1 - 2.1e-16 59.6 0.4 3.5e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 PUA domain PseudoU_synth_2 PF00849.22 EQB61861.1 - 0.0084 16.2 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0113 PF03657.13 EQB61861.1 - 0.013 15.7 0.1 0.074 13.3 0.0 2.1 2 0 0 2 2 2 0 UPF0113 PUA domain WD40_like PF17005.5 EQB61862.1 - 0.00094 18.6 11.5 0.05 12.9 0.8 2.6 1 1 1 3 3 3 2 WD40-like domain CAF1C_H4-bd PF12265.8 EQB61862.1 - 0.022 15.0 0.1 0.056 13.7 0.1 1.7 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EQB61862.1 - 1.1 10.3 12.4 1.4 9.9 0.2 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat PGI PF00342.19 EQB61863.1 - 1.5e-63 215.1 4.1 2.1e-63 214.6 4.1 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase BIR PF00653.21 EQB61865.1 - 3.6e-15 56.4 1.6 3.6e-15 56.4 1.6 2.0 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 EQB61865.1 - 0.00018 21.5 3.8 0.00025 21.1 3.2 1.6 1 1 0 1 1 1 1 C3HC zinc finger-like GTP_EFTU PF00009.27 EQB61867.1 - 4e-38 130.9 0.1 5.3e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EQB61867.1 - 3.4e-21 75.6 0.0 7.6e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EQB61867.1 - 9.6e-06 25.9 0.1 2.6e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 EQB61867.1 - 2.8e-05 23.6 0.1 0.00014 21.3 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EQB61867.1 - 0.0015 18.6 0.2 0.0091 16.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EQB61867.1 - 0.022 14.1 2.7 0.037 13.3 0.1 2.5 3 1 0 3 3 3 0 Septin MiaE_2 PF13794.6 EQB61867.1 - 0.11 12.1 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like RINGv PF12906.7 EQB61868.1 - 0.014 15.5 0.5 0.017 15.2 0.5 1.2 1 0 0 1 1 1 0 RING-variant domain PH_17 PF18012.1 EQB61869.1 - 0.13 12.0 0.2 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 PH domain Prefoldin_2 PF01920.20 EQB61870.1 - 0.0073 16.3 7.9 0.0073 16.3 7.9 4.7 1 1 2 3 3 3 1 Prefoldin subunit Shugoshin_N PF07558.11 EQB61870.1 - 0.035 14.0 0.3 0.035 14.0 0.3 5.4 5 1 1 6 6 6 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 EQB61870.1 - 0.054 13.7 1.0 0.054 13.7 1.0 5.5 5 1 1 6 6 6 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 EQB61870.1 - 0.073 12.9 42.3 1.1 9.1 7.4 3.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2353 PF09789.9 EQB61870.1 - 0.11 11.8 31.3 0.14 11.5 31.3 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Leu_zip PF15294.6 EQB61870.1 - 0.41 10.1 34.6 4.5 6.7 6.9 3.0 1 1 2 3 3 3 0 Leucine zipper ADIP PF11559.8 EQB61870.1 - 0.44 10.6 36.3 1.7 8.7 5.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 EQB61870.1 - 4.8 7.6 28.2 1.9 8.9 6.9 3.0 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region zinc_ribbon_10 PF10058.9 EQB61872.1 - 1.1e-12 47.5 1.9 1.7e-12 46.9 1.9 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF3784 PF12650.7 EQB61872.1 - 0.0055 16.9 2.7 0.0055 16.9 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3784) DUF5561 PF17716.1 EQB61872.1 - 0.019 14.3 2.0 0.027 13.8 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5561) DUF3810 PF12725.7 EQB61872.1 - 0.042 13.2 2.0 0.051 12.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4181 PF13789.6 EQB61872.1 - 0.042 14.1 7.6 0.041 14.1 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) zf-AD PF07776.15 EQB61872.1 - 0.073 13.3 1.3 14 6.0 0.1 2.6 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF1512 PF07431.12 EQB61872.1 - 0.1 11.6 1.5 0.14 11.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) COX16 PF14138.6 EQB61872.1 - 0.1 13.1 0.6 0.21 12.1 0.6 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 EQB61872.1 - 5.2 7.7 6.9 3.8 8.1 0.2 2.7 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II DS PF01916.17 EQB61873.1 - 5.1e-114 380.4 0.3 5.8e-114 380.2 0.3 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_C97 PF05903.14 EQB61874.1 - 9.3e-29 100.2 0.7 1.1e-28 100.0 0.7 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EQB61874.1 - 3.5e-05 24.1 0.0 4.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase LRR_8 PF13855.6 EQB61875.1 - 1.4e-09 37.6 42.9 0.0001 22.0 10.9 4.7 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EQB61875.1 - 5.6e-05 23.4 68.5 0.0021 18.4 6.7 6.3 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) 4HBT_2 PF13279.6 EQB61875.1 - 0.46 11.0 3.5 23 5.5 0.0 2.6 1 1 1 2 2 2 0 Thioesterase-like superfamily La PF05383.17 EQB61876.1 - 2.6e-08 33.8 0.2 9.8e-08 31.9 0.2 2.0 1 0 0 1 1 1 1 La domain DUF4284 PF14112.6 EQB61876.1 - 0.024 15.6 4.9 0.024 15.6 4.9 2.5 1 1 1 2 2 2 0 Immunity protein 22 DUF3069 PF11269.8 EQB61876.1 - 0.053 13.8 0.1 0.053 13.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3069) APP_N PF02177.16 EQB61876.1 - 0.73 10.2 4.2 0.39 11.1 2.1 1.7 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding Proteasome PF00227.26 EQB61877.1 - 4.5e-47 160.0 0.6 5.4e-47 159.7 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2415 PF10313.9 EQB61879.1 - 7e-08 32.3 0.0 1.8e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) EF-hand_1 PF00036.32 EQB61880.1 - 2.1e-09 36.3 2.6 8.6e-05 21.8 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EQB61880.1 - 1.3e-07 31.0 1.4 0.036 14.0 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EQB61880.1 - 1.3e-07 32.0 2.3 4.7e-05 23.8 1.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EQB61880.1 - 7.7e-05 22.5 0.8 0.0061 16.4 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EQB61880.1 - 0.002 18.4 0.3 0.0076 16.6 0.2 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EQB61880.1 - 0.0047 16.4 0.9 0.064 12.8 0.0 2.9 3 0 0 3 3 3 1 EF hand IgaA PF07095.11 EQB61880.1 - 0.018 13.1 0.1 0.024 12.7 0.1 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA MMR_HSR1 PF01926.23 EQB61881.1 - 1.1e-14 54.4 0.1 1.9e-14 53.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EQB61881.1 - 2.7e-06 27.0 0.7 3.8e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EQB61881.1 - 0.00018 21.6 0.2 0.0018 18.3 0.2 2.8 1 1 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 EQB61881.1 - 0.0037 17.2 0.0 0.0086 16.0 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EQB61881.1 - 0.0076 15.7 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family IIGP PF05049.13 EQB61881.1 - 0.062 12.3 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) VPS28 PF03997.12 EQB61881.1 - 0.14 11.8 1.5 0.61 9.7 0.2 2.0 2 0 0 2 2 2 0 VPS28 protein DUF2476 PF10630.9 EQB61883.1 - 0.86 9.7 5.4 1.5 8.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2476) Thioredoxin_6 PF13848.6 EQB61885.1 - 4.3e-11 43.1 6.1 8.6e-09 35.6 0.2 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 EQB61885.1 - 2.4e-08 33.9 0.1 5.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EQB61885.1 - 0.0021 18.5 0.1 0.015 15.7 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 EQB61885.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 EQB61885.1 - 0.065 13.1 0.1 0.39 10.5 0.1 2.1 2 1 0 2 2 2 0 F plasmid transfer operon protein DUF5093 PF17011.5 EQB61886.1 - 6.3e-29 100.9 6.4 6.9e-29 100.8 6.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5093) Imm-NTF2 PF15655.6 EQB61887.1 - 0.014 15.6 0.8 0.023 15.0 0.7 1.5 1 1 0 1 1 1 0 NTF2 fold immunity protein Nop PF01798.18 EQB61888.1 - 3.2e-62 210.0 4.6 3.9e-62 209.7 4.6 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin BAR_3_WASP_bdg PF10456.9 EQB61888.1 - 0.0077 15.7 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Sua5_yciO_yrdC PF01300.18 EQB61889.1 - 6.2e-51 172.4 0.0 1.9e-50 170.8 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 EQB61889.1 - 6.9e-22 78.5 0.0 1.1e-21 77.8 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Spore_GerAC PF05504.11 EQB61889.1 - 0.0016 18.7 0.6 0.0038 17.5 0.3 1.9 1 1 1 2 2 2 1 Spore germination B3/ GerAC like, C-terminal XPG_I PF00867.18 EQB61890.1 - 1.6e-16 60.4 0.0 1.6e-16 60.4 0.0 3.6 3 1 1 4 4 4 1 XPG I-region XPG_I_2 PF12813.7 EQB61890.1 - 0.047 13.2 1.9 0.37 10.2 0.0 2.6 2 1 0 2 2 2 0 XPG domain containing LRR_8 PF13855.6 EQB61892.1 - 3.3e-18 65.2 21.3 4.8e-09 35.9 4.5 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EQB61892.1 - 6.2e-12 45.5 49.5 1.4e-05 25.3 12.4 3.7 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB61892.1 - 7.1e-05 22.8 24.4 0.42 11.3 0.5 5.3 3 1 1 4 4 4 3 Leucine Rich Repeat LRR_5 PF13306.6 EQB61892.1 - 0.0015 18.5 4.0 0.011 15.6 3.5 2.0 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EQB61892.1 - 0.37 11.0 0.1 0.37 11.0 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat FNIP PF05725.12 EQB61892.1 - 0.61 10.3 23.1 0.36 11.0 0.4 4.5 1 1 3 4 4 4 0 FNIP Repeat LRR_2 PF07723.13 EQB61892.1 - 1.4 9.7 8.5 3.8 8.3 1.9 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 EQB61893.1 - 5.3e-15 55.3 53.3 0.00013 22.2 2.5 4.9 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB61893.1 - 9.2e-11 41.3 45.6 4.7e-06 26.3 15.0 5.0 2 1 3 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 EQB61893.1 - 4.9e-05 22.9 18.8 0.0068 15.9 11.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Phage_min_tail PF05939.13 EQB61893.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein AAA PF00004.29 EQB61897.1 - 1.6e-46 158.0 0.0 3e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EQB61897.1 - 5.5e-10 39.0 0.1 1.3e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EQB61897.1 - 2.8e-08 33.9 0.0 7.2e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 EQB61897.1 - 4.4e-08 32.8 0.0 8.9e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EQB61897.1 - 3.8e-07 30.6 0.0 1.6e-05 25.4 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 EQB61897.1 - 9.3e-07 28.9 0.1 0.0016 18.3 0.0 2.7 3 0 0 3 3 3 2 NTPase AAA_2 PF07724.14 EQB61897.1 - 1.4e-06 28.6 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EQB61897.1 - 4.2e-06 27.3 0.0 9.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EQB61897.1 - 3.8e-05 24.0 1.6 0.0052 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EQB61897.1 - 0.00048 19.4 0.0 0.0012 18.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EQB61897.1 - 0.00081 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EQB61897.1 - 0.00096 19.2 0.0 0.0035 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EQB61897.1 - 0.0011 19.3 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 EQB61897.1 - 0.0013 18.7 0.0 0.0045 17.0 0.0 1.7 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EQB61897.1 - 0.0023 17.9 0.1 0.075 12.9 0.0 2.3 1 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EQB61897.1 - 0.0037 17.4 0.0 0.0082 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EQB61897.1 - 0.0039 17.4 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EQB61897.1 - 0.0039 16.6 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein TIP49 PF06068.13 EQB61897.1 - 0.0041 16.4 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 EQB61897.1 - 0.0047 16.6 0.2 0.063 13.0 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 EQB61897.1 - 0.0049 16.4 0.1 0.01 15.4 0.1 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EQB61897.1 - 0.0054 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EQB61897.1 - 0.006 16.0 0.1 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EQB61897.1 - 0.0077 16.0 0.2 0.029 14.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EQB61897.1 - 0.014 15.3 1.4 0.083 12.8 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EQB61897.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EQB61897.1 - 0.029 14.2 0.0 0.089 12.7 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EQB61897.1 - 0.033 14.5 0.1 0.08 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EQB61897.1 - 0.036 14.6 0.3 0.19 12.2 0.0 2.2 2 2 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 EQB61897.1 - 0.041 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EQB61897.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AFG1_ATPase PF03969.16 EQB61897.1 - 0.083 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.18 EQB61897.1 - 0.11 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 EQB61897.1 - 0.13 11.8 0.3 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EQB61897.1 - 0.18 11.5 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pkinase PF00069.25 EQB61898.1 - 8.9e-50 169.5 0.0 1.7e-49 168.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB61898.1 - 1.4e-19 70.4 0.0 8.8e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EQB61898.1 - 4.3e-05 22.5 0.0 5.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EQB61898.1 - 0.0011 18.7 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EQB61898.1 - 0.0025 17.8 0.0 0.0054 16.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EQB61898.1 - 0.036 13.7 0.4 0.072 12.7 0.4 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EQB61898.1 - 0.14 11.4 0.0 38 3.5 0.0 2.9 3 0 0 3 3 3 0 Kinase-like Helitron_like_N PF14214.6 EQB61899.1 - 0.11 12.7 1.7 0.21 11.8 1.7 1.6 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DASH_Duo1 PF08651.10 EQB61899.1 - 8.7 6.2 12.3 4 7.3 0.7 3.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 Sec7 PF01369.20 EQB61900.1 - 1e-17 64.4 4.2 1e-17 64.4 4.2 3.9 2 1 0 3 3 3 1 Sec7 domain NifU_N PF01592.16 EQB61902.1 - 1.3e-53 180.6 0.1 1.4e-53 180.4 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Med6 PF04934.14 EQB61903.1 - 4.9e-25 87.9 4.8 5.8e-25 87.6 4.8 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF249 PF03158.13 EQB61903.1 - 0.0084 15.8 2.5 0.016 14.9 2.5 1.5 1 0 0 1 1 1 1 Multigene family 530 protein Pox_A_type_inc PF04508.12 EQB61904.1 - 1.2 9.1 6.7 1.3 9.0 1.3 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3347 PF11827.8 EQB61905.1 - 0.0031 17.7 1.6 0.0039 17.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3347) CTNNBL PF08216.11 EQB61905.1 - 0.012 15.8 1.2 0.012 15.8 1.2 1.6 1 1 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear 3H PF02829.14 EQB61905.1 - 0.039 14.2 0.7 0.71 10.2 0.4 2.2 2 0 0 2 2 2 0 3H domain Brix PF04427.18 EQB61906.1 - 2.4e-14 53.9 0.1 2.8e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.23 EQB61907.1 - 6.7e-49 166.5 0.5 4.2e-48 163.9 0.2 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EQB61907.1 - 1e-19 70.9 0.1 9.7e-18 64.5 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EQB61907.1 - 2.4e-07 30.2 0.1 1.5e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 EQB61907.1 - 2.5e-07 30.5 4.0 1.1e-06 28.5 4.0 2.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EQB61907.1 - 0.019 15.0 0.1 0.098 12.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 EQB61908.1 - 0.011 15.9 0.4 0.59 10.4 0.0 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain SLIDE PF09111.10 EQB61908.1 - 0.02 14.9 2.1 0.043 13.8 0.1 2.7 3 0 0 3 3 3 0 SLIDE Rap1_C PF11626.8 EQB61908.1 - 0.04 14.0 0.0 6.1 7.0 0.0 2.9 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TAFII55_N PF04658.13 EQB61909.1 - 1e-22 80.6 4.0 1e-22 80.6 4.0 2.6 2 1 0 2 2 2 1 TAFII55 protein conserved region GCD14 PF08704.10 EQB61909.1 - 0.6 9.7 3.8 0.19 11.4 0.5 1.7 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit ATP-synt_E PF05680.12 EQB61909.1 - 6.5 7.2 10.5 4.4 7.7 4.8 2.3 1 1 1 2 2 2 0 ATP synthase E chain P53_tetramer PF07710.11 EQB61910.1 - 0.0019 17.5 0.0 0.0071 15.7 0.0 2.1 2 0 0 2 2 2 1 P53 tetramerisation motif Myosin_head PF00063.21 EQB61912.1 - 2.4e-35 122.0 16.2 2.5e-28 98.7 11.1 2.6 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 EQB61912.1 - 0.0027 18.1 0.0 0.0039 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EQB61912.1 - 0.0046 16.3 0.0 0.011 15.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 EQB61912.1 - 0.014 15.4 0.0 0.014 15.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB61912.1 - 0.099 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EQB61912.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.9 3 1 1 4 4 4 0 RNA helicase T2SSE PF00437.20 EQB61912.1 - 4.8 6.2 6.2 0.37 9.8 1.3 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein LRRNT PF01462.18 EQB61913.1 - 0.49 10.1 4.2 11 5.8 0.3 2.4 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF4789 PF16033.5 EQB61914.1 - 0.029 14.9 3.1 1.8 9.1 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4789) JHBP PF06585.11 EQB61914.1 - 0.049 12.8 1.1 0.049 12.8 1.1 1.6 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) TBP PF00352.21 EQB61916.1 - 7.5e-66 218.1 1.0 4.5e-32 109.8 0.3 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EQB61916.1 - 2.2e-06 27.7 0.1 0.01 15.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EQB61916.1 - 0.11 12.3 0.1 0.63 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) TBP PF00352.21 EQB61917.1 - 1.5e-28 98.5 0.5 6.7e-14 51.6 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EQB61917.1 - 0.076 13.1 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3378) zf-ZPR1 PF03367.13 EQB61918.1 - 8.2e-17 61.5 3.7 1.1e-16 61.1 3.7 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain RCC1 PF00415.18 EQB61919.1 - 1.6e-49 166.3 0.0 2.1e-09 37.8 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EQB61919.1 - 2.7e-26 90.8 14.7 8.3e-06 25.5 0.0 6.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EQB61919.1 - 0.15 12.4 0.0 1.1e+02 3.1 0.0 3.7 3 1 1 4 4 4 0 Putative heavy-metal chelation tRNA_bind PF01588.20 EQB61921.1 - 5.4e-24 84.1 0.8 9.9e-24 83.3 0.8 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain SLC35F PF06027.12 EQB61921.1 - 0.022 14.3 1.8 0.036 13.6 1.8 1.4 1 0 0 1 1 1 0 Solute carrier family 35 DUF4508 PF14969.6 EQB61923.1 - 0.067 13.4 0.5 0.067 13.4 0.5 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4508) bPH_3 PF14470.6 EQB61923.1 - 0.44 10.9 7.0 0.13 12.6 2.4 2.2 1 1 1 2 2 2 0 Bacterial PH domain Ras PF00071.22 EQB61925.1 - 4.6e-34 117.4 0.2 5.5e-34 117.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB61925.1 - 4.6e-30 104.3 0.1 5.6e-30 104.0 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB61925.1 - 2.7e-11 43.2 0.1 3.1e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EQB61925.1 - 1.1e-08 35.1 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EQB61925.1 - 0.00019 20.7 3.3 0.62 9.2 1.2 3.0 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 EQB61925.1 - 0.00071 19.5 0.1 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EQB61925.1 - 0.00075 18.9 0.0 0.00093 18.6 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EQB61925.1 - 0.0019 17.8 0.8 0.09 12.3 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EQB61925.1 - 0.0027 16.8 0.1 0.0031 16.6 0.1 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EQB61925.1 - 0.0027 17.5 0.2 0.0071 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EQB61925.1 - 0.0042 17.0 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 NTPase Septin PF00735.18 EQB61925.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 EQB61925.1 - 0.013 15.0 0.2 0.09 12.3 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Pox_A32 PF04665.12 EQB61925.1 - 0.016 14.7 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein TsaE PF02367.17 EQB61925.1 - 0.017 15.1 0.2 0.022 14.8 0.2 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EQB61925.1 - 0.031 14.7 0.1 0.088 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EQB61925.1 - 0.035 13.3 0.1 0.045 12.9 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 EQB61925.1 - 0.053 13.8 0.0 0.086 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF4981 PF16353.5 EQB61925.1 - 0.054 14.0 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function(DUF4981) AAA PF00004.29 EQB61925.1 - 0.058 13.8 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EQB61925.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 EQB61925.1 - 0.092 12.3 0.4 2 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EQB61925.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EQB61925.1 - 0.12 12.1 0.2 3.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 EQB61925.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 EQB61925.1 - 0.15 12.6 0.3 0.48 11.0 0.3 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EQB61925.1 - 0.17 11.8 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 NACHT domain mRNA_triPase PF02940.15 EQB61926.1 - 2.2e-14 53.7 6.8 1.2e-07 31.7 0.1 3.1 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain PrgH PF09480.10 EQB61926.1 - 0.0005 19.5 0.5 0.00073 19.0 0.5 1.1 1 0 0 1 1 1 1 Type III secretion system protein PrgH-EprH (PrgH) MCR_D PF02505.14 EQB61927.1 - 0.047 13.5 0.1 0.098 12.5 0.0 1.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D Erf4 PF10256.9 EQB61929.1 - 0.0019 18.3 0.2 0.005 16.9 0.1 1.7 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family Lzipper-MIP1 PF14389.6 EQB61929.1 - 0.0073 16.6 0.4 3.9 7.8 0.1 2.2 2 0 0 2 2 2 2 Leucine-zipper of ternary complex factor MIP1 RVT_1 PF00078.27 EQB61932.1 - 7.3e-05 22.4 0.7 0.0046 16.5 0.1 2.8 1 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DASH_Dad3 PF08656.10 EQB61932.1 - 0.35 11.0 2.1 4.6 7.4 0.2 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad3 D5_N PF08706.11 EQB61934.1 - 3.2e-07 30.7 0.1 5.3e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 D5 N terminal like AAA_16 PF13191.6 EQB61934.1 - 0.18 12.2 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain D5_N PF08706.11 EQB61937.1 - 0.0042 17.4 0.0 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 D5 N terminal like MS_channel PF00924.18 EQB61937.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel SF3A3 PF16837.5 EQB61937.1 - 0.042 14.4 0.3 0.042 14.4 0.3 2.9 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Aminotran_5 PF00266.19 EQB61938.1 - 0.019 13.9 0.2 0.024 13.6 0.2 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Ndc80_HEC PF03801.13 EQB61938.1 - 0.022 14.4 3.2 0.026 14.1 3.2 1.3 1 1 0 1 1 1 0 HEC/Ndc80p family DnaJ PF00226.31 EQB61939.1 - 3.4e-05 23.9 0.6 4.9e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_M1 PF01433.20 EQB61940.1 - 1.2e-60 204.8 8.5 1.5e-60 204.5 8.5 1.1 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EQB61941.1 - 4e-21 76.0 1.0 4e-21 76.0 1.0 1.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M1_N PF17900.1 EQB61942.1 - 0.0001 22.6 0.8 0.00012 22.4 0.8 1.1 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3333 PF11812.8 EQB61942.1 - 0.074 13.2 0.1 0.1 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Ribosomal_L18 PF17135.4 EQB61943.1 - 3e-16 59.3 0.2 3.4e-16 59.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e ABC_tran PF00005.27 EQB61944.1 - 4.5e-25 88.8 0.0 8.6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EQB61944.1 - 9.4e-07 28.9 4.7 0.0059 16.4 0.2 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EQB61944.1 - 0.0015 18.0 7.0 0.22 11.0 0.1 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EQB61944.1 - 0.018 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 EQB61944.1 - 0.024 14.0 0.4 0.043 13.1 0.0 1.6 2 0 0 2 2 2 0 AIG1 family MMR_HSR1 PF01926.23 EQB61944.1 - 0.025 14.7 1.0 0.043 13.9 0.2 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EQB61944.1 - 0.042 13.6 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KH_2 PF07650.17 EQB61944.1 - 0.089 12.6 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 KH domain GP17 PF17420.2 EQB61944.1 - 0.1 12.8 0.4 0.1 12.8 0.4 2.6 3 0 0 3 3 3 0 Superinfection exclusion gene product 17 CBFB_NFYA PF02045.15 EQB61946.1 - 1.3e-19 70.5 5.2 2.4e-19 69.7 5.2 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SAE2 PF08573.10 EQB61946.1 - 0.16 13.1 2.2 0.19 12.8 2.2 1.3 1 1 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus EF-hand_6 PF13405.6 EQB61947.1 - 4.7e-07 29.2 2.0 9.5e-06 25.2 0.2 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 EQB61947.1 - 1.3e-05 24.5 0.4 3.6e-05 23.1 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EQB61947.1 - 1.6e-05 24.1 0.5 1.6e-05 24.1 0.5 3.2 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 EQB61947.1 - 2e-05 25.0 2.1 0.00016 22.1 2.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EQB61947.1 - 0.00037 20.3 1.7 0.017 15.0 0.3 3.1 2 2 1 3 3 3 2 EF-hand domain pair DUF4777 PF16007.5 EQB61947.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Nup54 PF13874.6 EQB61948.1 - 0.026 14.6 0.1 0.064 13.4 0.1 2.0 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1908 PF08926.11 EQB61948.1 - 0.071 12.2 1.7 0.085 11.9 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1908) Ank_2 PF12796.7 EQB61949.1 - 4.2e-12 46.5 1.3 3.5e-09 37.1 0.2 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EQB61949.1 - 8.7e-09 35.7 0.1 0.00038 20.9 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EQB61949.1 - 1.4e-08 34.3 0.8 0.00019 21.6 0.2 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EQB61949.1 - 2.6e-08 34.0 0.3 1.6e-05 25.0 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EQB61949.1 - 1.9e-07 31.2 3.1 9.3e-05 22.7 0.2 3.7 3 0 0 3 3 3 1 Ankyrin repeat YEATS PF03366.16 EQB61950.1 - 7.7e-20 70.7 1.7 1.5e-19 69.8 1.7 1.5 1 0 0 1 1 1 1 YEATS family PRESAN PF09687.10 EQB61950.1 - 0.0029 18.2 0.9 0.0029 18.2 0.9 2.0 2 0 0 2 2 2 1 Plasmodium RESA N-terminal TGT PF01702.18 EQB61951.1 - 1.8e-35 122.7 0.0 2.2e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase V-ATPase_C PF03223.15 EQB61951.1 - 0.042 13.2 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit C Ras PF00071.22 EQB61952.1 - 3.9e-35 120.8 0.6 4.5e-35 120.7 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB61952.1 - 1.1e-13 51.4 0.1 1.6e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EQB61952.1 - 3.7e-05 23.4 0.1 0.00091 18.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 EQB61952.1 - 0.0028 17.1 0.1 0.0034 16.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EQB61952.1 - 0.0041 16.9 0.2 0.096 12.4 0.2 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EQB61952.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EQB61952.1 - 0.019 14.8 0.1 0.29 11.0 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EQB61952.1 - 0.02 15.2 0.1 0.39 11.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EQB61952.1 - 0.055 13.2 0.2 6 6.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 EQB61952.1 - 0.061 12.7 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EQB61952.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region bZIP_1 PF00170.21 EQB61953.1 - 3.5e-07 30.2 4.1 3.5e-07 30.2 4.1 2.6 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EQB61953.1 - 6.4e-07 29.4 1.6 6.4e-07 29.4 1.6 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EQB61953.1 - 0.0015 19.0 3.9 0.0044 17.5 3.9 1.8 1 1 0 1 1 1 1 bZIP Maf transcription factor Med30 PF11315.8 EQB61953.1 - 0.0019 18.4 6.1 0.0027 17.9 6.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 30 DUF4806 PF16064.5 EQB61953.1 - 0.63 10.4 6.4 0.3 11.4 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4806) zf-RING_2 PF13639.6 EQB61954.1 - 2.4e-09 37.3 11.1 3.6e-09 36.8 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EQB61954.1 - 1.3e-06 28.0 8.7 2.4e-06 27.2 8.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EQB61954.1 - 2.5e-06 27.7 9.8 4.3e-06 26.9 9.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EQB61954.1 - 7.1e-06 25.8 11.2 1.1e-05 25.1 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EQB61954.1 - 1e-05 25.5 3.0 1.4e-05 25.0 3.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EQB61954.1 - 8e-05 22.6 5.4 0.00022 21.1 5.6 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EQB61954.1 - 0.0002 21.2 13.0 0.00032 20.5 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB61954.1 - 0.00044 20.1 11.1 0.00072 19.5 11.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zf_RING PF16744.5 EQB61954.1 - 0.0011 19.0 7.6 0.0023 18.0 7.6 1.5 1 1 0 1 1 1 1 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 EQB61954.1 - 0.0024 17.7 8.4 0.0038 17.1 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 EQB61954.1 - 0.031 14.6 3.9 0.91 9.9 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_17 PF17120.5 EQB61954.1 - 0.041 13.5 7.4 0.075 12.7 7.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EQB61954.1 - 0.077 13.1 10.7 0.14 12.3 10.7 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EQB61954.1 - 0.13 12.2 8.6 0.24 11.3 8.3 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EQB61954.1 - 0.15 12.3 11.2 3.3 8.0 11.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EQB61954.1 - 0.22 11.7 9.4 0.61 10.3 9.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2 PF00096.26 EQB61954.1 - 1 9.9 5.3 5.1 7.8 0.1 3.2 2 1 1 3 3 3 0 Zinc finger, C2H2 type PHD PF00628.29 EQB61954.1 - 1.2 9.1 10.8 2.5 8.1 10.8 1.6 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EQB61954.1 - 7.2 7.0 10.7 11 6.4 10.7 1.3 1 0 0 1 1 1 0 RING-like domain TMIE PF16038.5 EQB61955.1 - 0.069 13.0 3.6 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 TMIE protein Shisa PF13908.6 EQB61955.1 - 0.38 11.0 0.8 0.75 10.0 0.1 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF2070 PF09843.9 EQB61955.1 - 5.3 5.2 8.5 6.9 4.8 8.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Presenilin PF01080.17 EQB61956.1 - 0.034 12.9 3.5 0.03 13.1 3.5 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 EQB61956.1 - 0.37 11.4 6.6 0.37 11.3 6.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 EQB61956.1 - 2 6.9 12.6 1.8 7.0 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EQB61956.1 - 2 7.5 4.2 1.8 7.7 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4614 PF15391.6 EQB61956.1 - 3.1 7.7 20.9 4.2 7.3 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SNF2_N PF00176.23 EQB61958.1 - 5.2e-23 81.3 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF29 PF01724.16 EQB61958.1 - 0.051 13.8 0.2 0.051 13.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF29 DEAD PF00270.29 EQB61958.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.31 EQB61959.1 - 7.4e-21 74.6 0.1 3.1e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EQB61959.1 - 0.00026 19.8 0.1 0.00037 19.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain MBOAT PF03062.19 EQB61960.1 - 7.3e-17 61.7 37.7 1.6e-16 60.6 37.7 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EQB61960.1 - 1.5e-05 25.1 4.8 1.5e-05 25.1 4.8 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Acyltransferase PF01553.21 EQB61962.1 - 0.00011 21.8 0.1 0.00057 19.5 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase Transpos_assoc PF13963.6 EQB61964.1 - 5.7 7.3 11.0 24 5.3 0.1 4.0 4 0 0 4 4 4 0 Transposase-associated domain Helicase_RecD PF05127.14 EQB61965.1 - 2.3e-53 180.6 0.0 3.1e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Helicase GNAT_acetyltr_2 PF13718.6 EQB61965.1 - 1.2e-20 73.9 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 AAA_30 PF13604.6 EQB61965.1 - 0.0054 16.5 0.0 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EQB61965.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_D PF01813.17 EQB61967.1 - 3e-38 131.6 3.6 3.3e-38 131.5 3.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit D CENP-F_leu_zip PF10473.9 EQB61967.1 - 0.00068 19.7 2.8 0.0025 17.8 1.2 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pentapeptide PF00805.22 EQB61967.1 - 0.023 14.3 0.4 1.3 8.7 0.0 2.6 3 0 0 3 3 3 0 Pentapeptide repeats (8 copies) FRD2 PF03197.13 EQB61967.1 - 0.052 13.9 0.1 0.092 13.0 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage FRD2 protein Prefoldin PF02996.17 EQB61967.1 - 1.7 8.5 7.0 1.5 8.7 4.8 1.9 2 0 0 2 2 2 0 Prefoldin subunit Rer1 PF03248.13 EQB61969.1 - 3.7e-49 166.7 12.7 4e-49 166.6 12.7 1.0 1 0 0 1 1 1 1 Rer1 family ThrE PF06738.12 EQB61969.1 - 0.02 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative threonine/serine exporter SPC25 PF06703.11 EQB61969.1 - 2.6 7.8 14.0 1.6 8.5 3.4 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) PK PF00224.21 EQB61972.1 - 0.0025 16.8 1.0 0.0051 15.7 1.0 1.4 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Spc7 PF08317.11 EQB61972.1 - 0.044 12.7 0.3 0.044 12.7 0.3 4.4 3 1 1 4 4 4 0 Spc7 kinetochore protein Rotamase PF00639.21 EQB61972.1 - 2.3 9.2 6.0 1.7 9.6 0.3 2.6 2 0 0 2 2 2 0 PPIC-type PPIASE domain cNMP_binding PF00027.29 EQB61973.1 - 1.2e-16 60.5 0.0 2.5e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SirA PF10747.9 EQB61975.1 - 0.0027 18.0 8.1 0.0027 18.0 8.1 2.7 2 1 1 3 3 3 1 Sporulation inhibitor of replication protein SirA Cpn10 PF00166.21 EQB61975.1 - 0.076 13.1 1.1 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit IF4E PF01652.18 EQB61977.1 - 6.6e-29 100.8 2.8 8e-29 100.5 2.8 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RL11D PF11088.8 EQB61977.1 - 0.027 14.8 0.6 0.044 14.1 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 UQ_con PF00179.26 EQB61978.1 - 2.3e-29 101.9 0.3 2.6e-29 101.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CAF1 PF04857.20 EQB61979.1 - 4.8e-18 65.4 5.8 1.6e-11 44.0 0.1 2.9 1 1 1 2 2 2 2 CAF1 family ribonuclease Bmt2 PF11968.8 EQB61979.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Ribosomal_S4e PF00900.20 EQB61980.1 - 6e-24 83.7 0.2 6e-24 83.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 EQB61980.1 - 7e-17 61.3 1.8 1e-16 60.7 1.8 1.3 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 EQB61980.1 - 1.3e-08 34.3 0.1 2.3e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 EQB61980.1 - 2.8e-07 30.1 0.1 4.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EQB61980.1 - 0.00019 21.2 0.1 0.00059 19.6 0.1 1.9 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.11 EQB61980.1 - 0.086 12.3 4.2 1.4 8.3 0.2 2.2 1 1 1 2 2 2 0 Phage tail protein KOW PF00467.29 EQB61980.1 - 0.13 12.3 0.2 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 KOW motif OCRL_clath_bd PF16726.5 EQB61980.1 - 0.18 12.0 0.9 0.5 10.6 0.1 2.2 2 1 0 3 3 3 0 Inositol polyphosphate 5-phosphatase clathrin binding domain Kinesin PF00225.23 EQB61981.1 - 1.2e-83 280.8 8.1 1.2e-83 280.8 8.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EQB61981.1 - 5e-24 84.9 0.5 5e-24 84.9 0.5 2.6 3 0 0 3 3 3 1 Microtubule binding PspA_IM30 PF04012.12 EQB61981.1 - 0.0066 16.0 2.1 0.01 15.4 2.1 1.2 1 0 0 1 1 1 1 PspA/IM30 family OxoGdeHyase_C PF16870.5 EQB61981.1 - 0.25 11.0 3.4 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 2-oxoglutarate dehydrogenase C-terminal TPR_8 PF13181.6 EQB61982.1 - 0.00094 19.2 1.2 0.0018 18.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Pico_P2B PF01552.17 EQB61982.1 - 0.042 14.0 0.5 0.087 13.0 0.5 1.4 1 1 0 1 1 1 0 Picornavirus 2B protein TPR_2 PF07719.17 EQB61982.1 - 0.047 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat RVT_1 PF00078.27 EQB61984.1 - 4.5e-08 32.9 1.0 5e-08 32.7 1.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) vATP-synt_E PF01991.18 EQB61984.1 - 0.022 14.2 0.3 0.029 13.8 0.2 1.2 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit FlgN PF05130.12 EQB61984.1 - 0.058 13.9 0.2 0.097 13.2 0.2 1.3 1 0 0 1 1 1 0 FlgN protein RVT_1 PF00078.27 EQB61985.1 - 9.7e-08 31.8 0.3 2.9e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3394 PF11874.8 EQB61986.1 - 0.064 12.9 2.0 0.087 12.5 2.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3394) DUF5301 PF17225.3 EQB61986.1 - 0.43 11.0 4.6 20 5.7 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) PTP2 PF17022.5 EQB61988.1 - 8.2e-39 133.5 19.9 1.1e-38 133.1 19.9 1.0 1 0 0 1 1 1 1 Polar tube protein 2 from Microsporidia PmbA_TldD PF01523.16 EQB61988.1 - 0.023 14.5 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Putative modulator of DNA gyrase DP PF08781.10 EQB61989.1 - 1.4e-10 41.2 7.6 2.2e-10 40.6 7.6 1.3 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 EQB61989.1 - 1e-09 38.3 1.5 2e-09 37.4 1.5 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain FISNA PF14484.6 EQB61989.1 - 0.0045 17.2 2.3 0.0095 16.1 1.8 1.9 1 1 0 1 1 1 1 Fish-specific NACHT associated domain tRNA-synt_1 PF00133.22 EQB61990.1 - 3.4e-29 101.6 5.4 2.1e-16 59.3 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EQB61990.1 - 1.8e-23 82.9 1.6 3.8e-10 39.1 0.3 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EQB61990.1 - 1.3e-10 41.2 5.9 2.8e-09 36.7 0.1 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EQB61990.1 - 0.0098 14.8 1.7 0.52 9.2 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (K) zf-CCCH_3 PF15663.5 EQB61991.1 - 6.6e-16 58.5 8.7 6.6e-16 58.5 8.7 1.7 2 0 0 2 2 2 1 Zinc-finger containing family Homeodomain PF00046.29 EQB61992.1 - 3.1e-09 36.6 0.0 5.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EQB61992.1 - 0.0038 17.1 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdjO PF14169.6 EQB61994.1 - 0.0094 15.7 0.5 0.022 14.5 0.3 1.8 2 0 0 2 2 2 1 Cold-inducible protein YdjO DUF1599 PF07659.11 EQB61995.1 - 0.01 16.3 1.8 0.046 14.2 0.3 2.1 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 Arm-DNA-bind_2 PF12167.8 EQB61996.1 - 0.076 12.9 0.9 1.2 9.1 0.6 2.3 2 0 0 2 2 2 0 Arm DNA-binding domain MCM PF00493.23 EQB61998.1 - 2.5e-97 324.4 0.1 3.7e-97 323.8 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EQB61998.1 - 1.9e-26 92.3 0.0 3.9e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EQB61998.1 - 3e-16 59.4 0.0 4.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EQB61998.1 - 6.6e-11 42.0 0.2 6.9e-09 35.4 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EQB61998.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EQB61998.1 - 0.00069 19.3 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 EQB61998.1 - 0.0011 18.8 0.1 0.0043 16.9 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EQB61998.1 - 0.062 13.7 1.6 0.21 12.0 0.1 2.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EQB61998.1 - 0.11 12.3 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA lid domain AAA_30 PF13604.6 EQB61998.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Asn_synthase PF00733.21 EQB61999.1 - 9.5e-11 41.9 0.0 2.2e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EQB61999.1 - 0.032 14.1 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain PAXNEB PF05625.11 EQB62000.1 - 5.2e-11 42.3 7.3 0.0043 16.2 0.1 4.0 1 1 2 4 4 4 4 PAXNEB protein Nop PF01798.18 EQB62001.1 - 6.9e-78 261.3 1.1 1.2e-77 260.5 1.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Filo_VP24 PF06389.11 EQB62001.1 - 0.014 14.9 4.0 0.019 14.5 1.0 2.4 2 1 1 3 3 3 0 Filovirus membrane-associated protein VP24 Transket_pyr PF02779.24 EQB62002.1 - 3.7e-32 111.4 0.0 5.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EQB62002.1 - 0.064 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Transketolase, C-terminal domain Transketolase_N PF00456.21 EQB62003.1 - 2.7e-91 306.0 0.0 4.8e-91 305.2 0.0 1.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 EQB62003.1 - 0.00041 19.6 0.1 0.0091 15.2 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EQB62003.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EQB62003.1 - 0.068 12.1 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component DUF295 PF03478.18 EQB62003.1 - 0.19 11.3 0.9 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF295) TK PF00265.18 EQB62004.1 - 8.5e-19 68.1 3.6 1.1e-18 67.8 3.6 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 EQB62004.1 - 0.007 16.4 4.1 0.018 15.0 4.0 1.8 1 1 0 1 1 1 1 AAA domain CofC PF01983.16 EQB62004.1 - 0.011 15.0 0.2 0.011 14.9 0.2 1.3 1 0 0 1 1 1 0 Guanylyl transferase CofC like AAA_30 PF13604.6 EQB62004.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 EQB62005.1 - 2.5e-09 37.3 2.6 2.5e-09 37.3 2.6 2.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 EQB62005.1 - 7.5e-09 35.3 1.7 2.9e-08 33.4 1.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EQB62005.1 - 8e-07 29.0 0.3 8e-07 29.0 0.3 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EQB62005.1 - 7.3e-06 25.7 2.4 2.4e-05 24.1 2.4 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EQB62005.1 - 0.00026 21.2 4.4 0.00035 20.8 2.1 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EQB62005.1 - 0.00031 20.6 1.7 0.00091 19.1 1.7 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EQB62005.1 - 0.00045 20.3 2.7 0.0023 18.0 2.9 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EQB62005.1 - 0.0028 17.4 0.3 0.0028 17.4 0.3 2.2 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EQB62005.1 - 0.005 16.4 3.2 0.005 16.4 3.2 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF4246 PF14033.6 EQB62005.1 - 0.0068 15.6 0.5 0.008 15.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) zf-RING_11 PF17123.5 EQB62005.1 - 0.016 14.9 1.6 0.016 14.9 1.6 2.7 3 0 0 3 3 3 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EQB62005.1 - 1.3 9.2 5.7 0.38 10.8 1.7 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 EQB62005.1 - 2.8 8.1 6.7 1.1 9.5 2.3 2.6 1 1 1 2 2 2 0 FYVE zinc finger TPR_8 PF13181.6 EQB62007.1 - 2.9e-06 27.0 24.1 0.085 13.1 0.4 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EQB62007.1 - 1.8e-05 24.5 14.2 0.099 12.8 0.3 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EQB62007.1 - 2.1 8.3 24.6 2.6 8.0 1.3 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Rad17 PF03215.15 EQB62008.1 - 5.6e-05 23.1 1.7 6e-05 23.0 0.4 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 EQB62008.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EQB62008.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Polysacc_deac_1 PF01522.21 EQB62009.1 - 0.0024 17.8 0.0 0.012 15.5 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF3452 PF11934.8 EQB62009.1 - 0.082 12.5 0.9 0.17 11.5 0.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) LRR_3 PF07725.12 EQB62009.1 - 0.41 10.6 2.1 3.3 7.7 0.4 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat Glycolytic PF00274.19 EQB62011.1 - 2.6e-94 315.8 0.0 2.9e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Homeodomain PF00046.29 EQB62012.1 - 2.2e-12 46.6 0.2 3.4e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 EQB62013.1 - 8.4e-06 25.5 0.1 8.7e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Homeodomain DUF866 PF05907.13 EQB62014.1 - 1.1e-08 35.2 1.5 1.2e-08 35.0 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) NusG_add PF18298.1 EQB62014.1 - 0.087 13.0 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 NusG additional domain Dynein_light PF01221.18 EQB62015.1 - 1.2e-13 51.2 0.2 1.8e-13 50.6 0.2 1.4 1 1 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 EQB62015.1 - 0.00082 20.0 0.0 0.0011 19.6 0.0 1.3 1 0 0 1 1 1 1 Ground-like domain DUF5611 PF18446.1 EQB62015.1 - 0.0072 17.2 0.7 0.017 16.0 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5611) Phage_holin_2_1 PF04971.12 EQB62015.1 - 0.098 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage P21 holin S MukF_C PF17193.4 EQB62015.1 - 0.14 12.3 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 MukF C-terminal domain AAA_11 PF13086.6 EQB62016.1 - 1.3e-24 87.4 3.8 4.6e-13 49.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EQB62016.1 - 1.2e-09 38.3 1.5 1.4e-07 31.5 1.5 2.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EQB62016.1 - 2.1e-07 30.8 0.1 2.1e-07 30.8 0.1 2.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EQB62016.1 - 2.5e-07 31.1 0.0 5.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EQB62016.1 - 5.6e-07 29.5 0.0 9.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EQB62016.1 - 0.032 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_16 PF13191.6 EQB62016.1 - 0.053 13.9 0.0 0.17 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EQB62016.1 - 0.057 13.4 4.1 0.074 13.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EQB62016.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Peptidase_S24 PF00717.23 EQB62016.1 - 0.16 11.9 2.8 8.1 6.5 0.0 3.6 4 0 0 4 4 4 0 Peptidase S24-like zf-C2H2_2 PF12756.7 EQB62017.1 - 0.0019 18.5 4.3 0.004 17.5 4.3 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF4488 PF14869.6 EQB62017.1 - 0.038 13.9 2.8 0.061 13.2 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4488) zf-nanos PF05741.13 EQB62017.1 - 0.079 13.2 3.0 0.14 12.4 1.7 1.9 2 0 0 2 2 2 0 Nanos RNA binding domain FliO PF04347.13 EQB62017.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO LRR_4 PF12799.7 EQB62019.1 - 3.6e-27 94.0 77.2 2.9e-05 24.3 1.4 8.0 3 3 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB62019.1 - 5.7e-27 93.3 58.1 3.2e-07 30.0 10.9 7.1 3 2 3 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 EQB62019.1 - 3.8e-06 26.5 32.0 0.0063 16.0 1.7 4.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 EQB62019.1 - 0.08 12.9 35.8 0.051 13.5 3.5 4.0 1 1 3 4 4 4 0 BspA type Leucine rich repeat region (6 copies) MRP-L51 PF10244.9 EQB62021.1 - 0.091 13.0 0.5 0.091 13.0 0.5 2.2 1 1 2 3 3 3 0 Mitochondrial ribosomal subunit ParA PF10609.9 EQB62022.1 - 1.9e-58 197.9 0.0 2.1e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 EQB62022.1 - 2e-14 53.9 1.8 1.6e-13 51.0 1.8 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EQB62022.1 - 2.1e-10 40.7 0.0 2.7e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EQB62022.1 - 1.1e-05 24.8 7.5 0.00014 21.1 0.1 3.1 1 1 1 3 3 3 2 Anion-transporting ATPase AAA_26 PF13500.6 EQB62022.1 - 0.00026 20.9 1.3 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EQB62022.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 EQB62022.1 - 0.0029 17.1 0.1 0.18 11.3 0.1 2.1 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 EQB62022.1 - 0.013 15.3 0.3 0.024 14.4 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Ras PF00071.22 EQB62023.1 - 1.9e-54 183.6 0.5 2.2e-54 183.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EQB62023.1 - 1.1e-30 106.3 0.2 1.7e-30 105.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EQB62023.1 - 4.4e-12 45.8 0.0 4.9e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EQB62023.1 - 5.1e-06 26.5 0.0 7.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EQB62023.1 - 2.5e-05 23.9 0.0 7.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EQB62023.1 - 7.4e-05 22.2 0.1 8.6e-05 22.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EQB62023.1 - 0.0033 17.4 0.0 0.05 13.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Ribosomal_L4 PF00573.22 EQB62024.1 - 7.2e-37 126.9 0.0 9.3e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family SRP19 PF01922.17 EQB62025.1 - 2.1e-21 76.7 0.5 2.8e-21 76.3 0.5 1.4 1 1 0 1 1 1 1 SRP19 protein SPATA9 PF15824.5 EQB62025.1 - 0.0015 17.9 0.4 0.0024 17.2 0.4 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 9 IFS PF16718.5 EQB62025.1 - 0.0088 16.2 0.3 0.014 15.5 0.3 1.4 1 1 0 1 1 1 1 Immunity factor for SPN DUF5092 PF17010.5 EQB62027.1 - 3.2e-54 183.2 14.4 6.8e-54 182.2 14.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5092) HTH_Bact PF18768.1 EQB62027.1 - 0.0065 16.0 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix bacterial domain TPR_8 PF13181.6 EQB62028.1 - 8.9e-09 34.9 4.2 0.0022 18.1 0.6 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EQB62028.1 - 1.8e-06 27.5 2.9 0.002 17.9 0.5 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EQB62028.1 - 3.3e-05 23.7 9.6 0.0011 18.9 1.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EQB62028.1 - 0.019 15.0 0.1 0.057 13.5 0.1 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat WIYLD PF10440.9 EQB62028.1 - 0.032 14.0 1.3 0.14 12.0 0.5 2.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Kinesin PF00225.23 EQB62029.1 - 3.6e-39 134.6 1.8 3.6e-39 134.6 1.8 1.5 2 0 0 2 2 2 1 Kinesin motor domain DivIC PF04977.15 EQB62029.1 - 0.025 14.3 2.2 0.059 13.1 1.2 2.0 1 1 1 2 2 2 0 Septum formation initiator FRQ PF09421.10 EQB62029.1 - 0.17 9.9 0.7 0.2 9.6 0.7 1.1 1 0 0 1 1 1 0 Frequency clock protein Kinesin PF00225.23 EQB62030.1 - 1.6e-30 106.2 0.8 2e-30 105.9 0.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EQB62030.1 - 5.4e-21 75.1 0.5 5.4e-21 75.1 0.5 1.7 2 0 0 2 2 2 1 Microtubule binding AAA_7 PF12775.7 EQB62030.1 - 0.058 12.9 0.5 0.2 11.1 0.2 1.9 1 1 1 2 2 2 0 P-loop containing dynein motor region Ribosomal_S4e PF00900.20 EQB62031.1 - 4.7e-24 84.1 0.2 4.7e-24 84.1 0.2 1.6 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 EQB62031.1 - 1.2e-10 41.3 0.1 1.7e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EQB62031.1 - 2.4e-07 30.3 0.1 3.9e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EQB62031.1 - 0.00015 21.5 0.1 0.00047 19.9 0.1 1.8 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.11 EQB62031.1 - 0.095 12.1 5.0 9.2 5.6 4.9 2.2 1 1 0 1 1 1 0 Phage tail protein KOW PF00467.29 EQB62031.1 - 0.099 12.6 0.2 0.49 10.4 0.1 2.3 2 0 0 2 2 2 0 KOW motif CAF1 PF04857.20 EQB62032.1 - 1.7e-11 43.9 4.0 0.00013 21.3 2.0 2.9 1 1 1 2 2 2 2 CAF1 family ribonuclease Bmt2 PF11968.8 EQB62032.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Herpes_U44 PF04533.13 EQB62033.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpes virus U44 protein E1_dh PF00676.20 EQB62034.1 - 4.6e-72 242.5 0.0 5.8e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EQB62034.1 - 6.7e-05 22.2 0.5 0.00011 21.5 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EQB62034.1 - 0.00096 19.0 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1287 PF06940.11 EQB62036.1 - 0.0014 18.3 0.4 0.0027 17.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1287) SR-25 PF10500.9 EQB62037.1 - 0.012 15.3 5.9 0.015 15.0 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.8 EQB62037.1 - 0.034 13.7 3.5 0.045 13.3 3.5 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SR-25 PF10500.9 EQB62038.1 - 0.011 15.4 5.9 0.013 15.2 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.8 EQB62038.1 - 0.027 14.1 3.4 0.034 13.8 3.4 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF4776 PF16003.5 EQB62039.1 - 0.021 13.8 8.6 0.026 13.5 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Goodbye PF17109.5 EQB62039.1 - 0.27 11.7 2.8 12 6.4 0.0 2.6 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain RNase_P_p30 PF01876.16 EQB62041.1 - 2.9e-17 62.8 3.0 4.4e-17 62.3 3.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 MCM_lid PF17855.1 EQB62042.1 - 4.5e-08 33.4 0.7 1.1e-07 32.2 0.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain Tautomerase_2 PF14552.6 EQB62042.1 - 0.016 15.3 0.1 0.042 14.0 0.1 1.7 1 1 1 2 2 2 0 Tautomerase enzyme Phage_min_cap2 PF06152.11 EQB62042.1 - 0.09 11.7 0.7 0.13 11.1 0.7 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 MCM PF00493.23 EQB62043.1 - 8.5e-92 306.3 1.1 1.2e-91 305.7 1.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EQB62043.1 - 2.2e-28 98.6 0.1 3.7e-28 97.9 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EQB62043.1 - 2.1e-08 33.8 0.1 5.6e-07 29.2 0.0 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EQB62043.1 - 0.00038 20.3 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EQB62043.1 - 0.00086 19.0 0.3 0.043 13.5 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain tRNA_anti-like PF12869.7 EQB62043.1 - 0.043 13.4 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 tRNA_anti-like Hydrolase PF00702.26 EQB62044.1 - 4.6e-08 33.6 0.0 8.2e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 EQB62045.1 - 1.7e-06 28.2 35.6 0.00023 21.5 1.6 5.0 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EQB62045.1 - 2.8e-06 27.0 14.8 1.8e-05 24.4 0.1 3.6 1 1 1 3 3 3 2 Leucine rich repeat Glyoxalase_2 PF12681.7 EQB62045.1 - 0.44 10.5 8.2 10 6.1 0.3 3.2 2 1 1 3 3 3 0 Glyoxalase-like domain CENP-L PF13092.6 EQB62047.1 - 0.0026 18.0 0.2 0.0098 16.1 0.2 2.1 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 LAGLIDADG_2 PF03161.13 EQB62047.1 - 2.1 8.3 8.0 0.21 11.6 1.9 2.3 2 2 1 3 3 3 0 LAGLIDADG DNA endonuclease family AAA PF00004.29 EQB62048.1 - 1.1e-12 48.6 0.1 2.1e-12 47.6 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EQB62048.1 - 4.1e-12 46.3 0.0 9.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 EQB62048.1 - 1.8e-08 34.5 0.1 7.4e-08 32.5 0.1 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EQB62048.1 - 9.3e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EQB62048.1 - 0.0052 16.0 0.1 0.0079 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EQB62048.1 - 0.0077 16.6 0.9 0.025 15.0 0.0 2.3 2 2 1 3 3 3 1 RNA helicase AAA_14 PF13173.6 EQB62048.1 - 0.0077 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EQB62048.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EQB62048.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EQB62048.1 - 0.028 14.4 0.0 0.099 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EQB62048.1 - 0.03 14.6 0.1 1.3 9.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EQB62048.1 - 0.048 12.6 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PTCB-BRCT PF12738.7 EQB62048.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain AAA_3 PF07726.11 EQB62048.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) BsuBI_PstI_RE PF06616.11 EQB62051.1 - 0.0014 17.9 0.4 0.0029 16.9 0.4 1.5 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain TraF PF13728.6 EQB62051.1 - 0.061 13.1 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein HSDR_N_2 PF13588.6 EQB62051.1 - 0.12 12.4 2.4 0.21 11.6 2.0 1.7 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) AGO_N PF18236.1 EQB62053.1 - 0.24 11.6 8.2 0.027 14.7 2.3 2.4 1 1 2 3 3 3 0 Argonaute N domain ASL_C PF08328.11 EQB62053.1 - 0.92 9.6 4.5 1.4 9.0 0.5 2.4 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Cytokin_check_N PF10407.9 EQB62054.1 - 0.23 11.4 6.7 4.9 7.2 0.6 3.3 1 1 2 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Csm1_N PF18504.1 EQB62055.1 - 0.021 15.2 2.1 0.023 15.0 0.7 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain UCH PF00443.29 EQB62057.1 - 1.3e-16 60.9 0.0 3.3e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Per1 PF04080.13 EQB62058.1 - 9.4e-07 28.8 19.1 4.9e-05 23.2 1.9 3.3 2 1 2 4 4 4 3 Per1-like family HlyIII PF03006.20 EQB62058.1 - 0.21 11.3 5.6 1.1 9.0 0.6 2.1 1 1 1 2 2 2 0 Haemolysin-III related UCH PF00443.29 EQB62059.1 - 2.2e-20 73.3 1.6 1.9e-17 63.6 1.6 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SOG2 PF10428.9 EQB62059.1 - 5.3 6.1 15.2 7.2 5.7 15.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3906 PF13046.6 EQB62061.1 - 0.89 9.7 4.2 14 5.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3906) Nod1 PF17114.5 EQB62061.1 - 1.1 9.4 10.9 7.2 6.8 0.5 3.4 1 1 2 3 3 3 0 Gef2-related medial cortical node protein Nod1 SOG2 PF10428.9 EQB62063.1 - 0.0023 17.2 2.2 0.0031 16.8 2.2 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein BRCT_assoc PF12820.7 EQB62063.1 - 0.0044 16.8 4.0 0.0044 16.8 4.0 1.5 2 0 0 2 2 2 1 Serine-rich domain associated with BRCT MRP-S31 PF15433.6 EQB62063.1 - 0.019 14.7 3.8 0.024 14.3 3.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Velvet PF11754.8 EQB62063.1 - 1.4 8.8 5.5 2 8.3 5.3 1.3 1 1 0 1 1 1 0 Velvet factor HECT PF00632.25 EQB62066.1 - 5.5e-80 269.1 9.6 5.5e-80 269.1 9.6 2.5 3 1 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF3194 PF11419.8 EQB62066.1 - 0.73 10.2 8.3 3.1 8.2 1.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3194) RVT_1 PF00078.27 EQB62067.1 - 4.5e-13 49.2 1.1 1.4e-12 47.6 0.3 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vac_ImportDeg PF09783.9 EQB62068.1 - 5.8e-17 62.0 10.0 5.2e-15 55.6 10.0 2.5 1 1 0 1 1 1 1 Vacuolar import and degradation protein ALMT PF11744.8 EQB62069.1 - 1.4 7.7 8.0 1.8 7.3 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Stork_head PF10264.9 EQB62070.1 - 0.053 13.7 0.1 7.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain DUF5343 PF17278.2 EQB62071.1 - 0.013 15.6 6.8 0.016 15.3 5.5 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5343) Arm_3 PF16186.5 EQB62071.1 - 1.1 8.9 7.6 0.51 9.9 2.3 2.8 2 1 0 2 2 2 0 Atypical Arm repeat Sec1 PF00995.23 EQB62072.1 - 6.2e-32 111.6 38.8 1.1e-30 107.5 38.8 2.7 1 1 0 1 1 1 1 Sec1 family Tim54 PF11711.8 EQB62073.1 - 6.3 5.5 6.6 2.4 6.9 0.0 2.0 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 CreD PF06123.12 EQB62074.1 - 0.043 12.6 0.2 0.066 12.0 0.2 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD DDE_Tnp_1_7 PF13843.6 EQB62075.1 - 1.9e-85 287.3 0.2 2.5e-85 286.9 0.2 1.2 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 EQB62075.1 - 4.8e-05 23.1 0.9 0.00053 19.7 0.1 2.3 1 1 1 2 2 2 1 Transposase DDE domain AMP-binding PF00501.28 EQB62076.1 - 1.5e-08 33.7 0.0 2.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EQB62076.1 - 4.7e-08 33.9 0.3 9e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DRMBL PF07522.14 EQB62077.1 - 1e-16 61.1 0.4 1e-16 61.1 0.4 2.2 2 1 0 2 2 2 1 DNA repair metallo-beta-lactamase SAP PF02037.27 EQB62079.1 - 3e-06 26.8 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 SAP domain Ribosomal_L14e PF01929.17 EQB62081.1 - 0.0029 18.1 0.4 0.0046 17.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 AIG2_2 PF13772.6 EQB62081.1 - 0.16 12.4 0.2 0.3 11.5 0.2 1.5 1 0 0 1 1 1 0 AIG2-like family Med21 PF11221.8 EQB62082.1 - 0.0095 16.2 7.9 0.027 14.7 7.9 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex FAM76 PF16046.5 EQB62082.1 - 0.12 11.7 9.8 0.15 11.4 9.8 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4094 PF13334.6 EQB62082.1 - 0.24 11.9 6.7 0.69 10.4 6.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) LMBR1 PF04791.16 EQB62082.1 - 0.76 8.6 8.4 0.91 8.3 8.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_2 PF07719.17 EQB62083.1 - 6.2e-08 32.2 1.6 0.054 13.6 0.3 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EQB62083.1 - 9.6e-07 28.4 1.9 0.34 10.8 0.4 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EQB62083.1 - 3.6e-05 24.0 0.0 1.2 9.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EQB62083.1 - 0.003 17.2 5.3 0.03 14.0 0.4 3.6 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.6 EQB62083.1 - 0.05 13.5 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EQB62083.1 - 0.18 12.1 9.1 0.071 13.3 0.8 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Ntox16 PF15523.6 EQB62084.1 - 0.04 14.1 1.6 0.091 13.0 1.6 1.6 1 0 0 1 1 1 0 Novel toxin 16 DDE_Tnp_1_7 PF13843.6 EQB62087.1 - 6.6e-49 167.1 0.2 7.8e-49 166.9 0.2 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 EQB62087.1 - 3.2e-06 26.9 1.0 2e-05 24.4 0.1 2.1 1 1 1 2 2 2 1 Transposase DDE domain DUF5572 PF17733.1 EQB62089.1 - 0.51 10.2 12.7 3.6 7.5 0.6 4.0 2 2 1 3 3 3 0 Family of unknown function (DUF5572) CdiA_C_tRNase PF18664.1 EQB62090.1 - 0.044 14.0 0.2 6.8 6.9 0.1 2.1 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain DUF5517 PF17639.2 EQB62092.1 - 0.0073 16.6 4.1 0.011 16.0 3.3 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF5517) MCRS_N PF13325.6 EQB62094.1 - 0.00019 21.5 1.7 0.00032 20.8 1.7 1.3 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein APC_u15 PF16636.5 EQB62094.1 - 1.8 9.1 10.3 0.14 12.6 4.5 2.1 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Helicase_C PF00271.31 EQB62095.1 - 4.4e-18 65.6 2.5 3.7e-17 62.7 0.0 2.8 3 1 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EQB62095.1 - 3.8e-16 59.5 9.1 9.5e-16 58.3 9.1 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 EQB62095.1 - 1e-07 31.7 0.2 2.5e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 RQC domain YfcL PF08891.11 EQB62095.1 - 0.072 13.4 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 YfcL protein Homeodomain PF00046.29 EQB62096.1 - 8.2e-18 64.0 2.7 1.6e-17 63.1 2.7 1.5 1 0 0 1 1 1 1 Homeodomain zf-RING_2 PF13639.6 EQB62097.1 - 6.4e-11 42.4 14.3 1.2e-10 41.5 14.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EQB62097.1 - 1.2e-06 28.3 12.3 2.1e-06 27.5 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EQB62097.1 - 2.6e-06 27.0 11.3 5.3e-06 26.1 11.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EQB62097.1 - 7.7e-06 26.1 11.9 2e-05 24.8 11.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EQB62097.1 - 2.2e-05 24.2 14.1 4.7e-05 23.2 14.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EQB62097.1 - 0.00094 19.1 16.1 0.0016 18.4 16.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EQB62097.1 - 0.0032 17.5 8.8 0.0099 15.9 8.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EQB62097.1 - 0.0072 16.3 15.8 0.015 15.3 15.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EQB62097.1 - 0.0089 15.6 11.8 0.013 15.1 11.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EQB62097.1 - 0.0091 15.8 14.8 0.015 15.2 14.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EQB62097.1 - 1.3 9.2 13.6 0.79 9.9 10.9 2.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EQB62097.1 - 1.6 8.8 11.2 6.5 6.9 11.2 2.2 1 1 0 1 1 1 0 Zinc-finger UQ_con PF00179.26 EQB62098.1 - 4.2e-26 91.3 0.2 4.5e-26 91.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF468 PF04318.12 EQB62098.1 - 0.054 14.2 1.2 0.11 13.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF468) Collectrin PF16959.5 EQB62098.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Renal amino acid transporter DUF5099 PF17025.5 EQB62099.1 - 9.3e-26 90.4 4.7 2.5e-24 85.8 4.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5099) Mnd1 PF03962.15 EQB62100.1 - 1.2e-22 80.0 1.4 1.2e-22 80.0 1.4 2.4 2 1 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EQB62100.1 - 4.5e-13 49.1 5.4 4.5e-13 49.1 5.4 2.8 1 1 0 2 2 2 1 Leucine zipper with capping helix domain Penicillinase_R PF03965.16 EQB62100.1 - 0.0038 17.6 3.3 0.018 15.4 0.6 2.4 2 1 1 3 3 3 1 Penicillinase repressor RNase_HII PF01351.18 EQB62100.1 - 0.045 13.6 6.9 0.071 12.9 6.9 1.3 1 0 0 1 1 1 0 Ribonuclease HII FUR PF01475.19 EQB62100.1 - 0.12 12.5 8.8 0.052 13.7 4.4 2.4 1 1 1 2 2 2 0 Ferric uptake regulator family Cob_adeno_trans PF01923.18 EQB62100.1 - 0.47 10.6 3.5 11 6.2 0.0 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DDE_Tnp_1_7 PF13843.6 EQB62101.1 - 2.9e-33 115.6 0.0 3.4e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF4070 PF13282.6 EQB62101.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4070) DND1_DSRM PF14709.7 EQB62106.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 LRR_8 PF13855.6 EQB62107.1 - 1.1e-28 98.8 60.9 3.9e-10 39.3 9.7 6.6 4 3 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 EQB62107.1 - 3.2e-18 65.5 78.9 0.00066 20.0 8.0 8.8 4 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB62107.1 - 7.4e-08 32.1 32.4 0.00016 21.2 7.0 4.0 1 1 3 4 4 4 3 Leucine-rich repeat CaM_binding PF07839.11 EQB62108.1 - 0.033 14.9 0.3 0.085 13.6 0.3 1.6 1 0 0 1 1 1 0 Plant calmodulin-binding domain AsnC_trans_reg2 PF17805.1 EQB62108.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AsnC-like ligand binding domain DUF896 PF05979.12 EQB62109.1 - 0.022 14.6 1.4 0.13 12.1 1.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF896) ABC_tran PF00005.27 EQB62111.1 - 7.1e-29 101.1 4.5 5.7e-19 69.0 0.2 3.2 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EQB62111.1 - 2.7e-23 81.8 0.2 2.7e-23 81.8 0.2 1.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EQB62111.1 - 1.1e-10 41.9 7.9 0.00042 20.2 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EQB62111.1 - 6.8e-10 38.7 3.0 1.4e-05 24.7 0.0 3.3 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EQB62111.1 - 0.00028 21.2 1.9 0.00085 19.6 0.2 2.6 3 1 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 EQB62111.1 - 0.0016 18.6 0.1 0.48 10.7 0.2 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EQB62111.1 - 0.0056 17.0 0.0 0.021 15.2 0.0 2.0 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EQB62111.1 - 0.0092 15.9 0.2 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 EQB62111.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EQB62111.1 - 0.026 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 EQB62111.1 - 0.036 13.1 0.1 0.07 12.2 0.1 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EQB62111.1 - 0.041 14.0 0.6 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EQB62111.1 - 0.041 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EQB62111.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.2 1 1 2 3 3 2 0 AAA domain Dynamin_N PF00350.23 EQB62111.1 - 0.12 12.4 3.5 0.38 10.8 0.0 2.9 2 1 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 EQB62111.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhetRS_B1 PF18262.1 EQB62111.1 - 0.22 11.8 1.5 0.59 10.4 0.1 2.3 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain CDC50 PF03381.15 EQB62112.1 - 2e-29 103.0 1.8 4.1e-19 69.2 0.4 2.2 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1638 PF07796.11 EQB62113.1 - 0.0045 17.1 0.5 0.012 15.7 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1638) DUF3410 PF11890.8 EQB62113.1 - 0.056 13.2 2.0 0.093 12.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) DUF2460 PF09343.10 EQB62113.1 - 0.088 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) DUF1419 PF07215.11 EQB62115.1 - 0.018 15.1 0.6 0.032 14.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) GerPE PF10970.8 EQB62116.1 - 0.0061 16.7 1.1 0.011 15.9 0.3 1.7 1 1 1 2 2 2 1 Spore germination protein GerPE HTH_41 PF14502.6 EQB62116.1 - 0.11 12.3 1.9 0.16 11.7 0.3 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain DUF4881 PF16222.5 EQB62117.1 - 0.091 12.6 0.3 0.59 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4881) Pkinase PF00069.25 EQB62119.1 - 2.1e-15 56.8 0.3 2.4e-15 56.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB62119.1 - 1.7e-10 40.7 0.3 1.8e-10 40.5 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Carm_PH PF17888.1 EQB62121.1 - 0.82 10.1 8.3 5.5 7.4 1.7 3.7 3 0 0 3 3 3 0 Carmil pleckstrin homology domain FtsH_ext PF06480.15 EQB62123.1 - 0.73 10.2 5.7 0.71 10.2 1.2 2.4 2 1 0 2 2 2 0 FtsH Extracellular LRR_8 PF13855.6 EQB62124.1 - 1.6e-34 117.5 81.6 1.1e-07 31.5 2.7 9.3 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EQB62124.1 - 3.5e-32 109.9 112.6 5.6e-05 23.4 4.6 11.5 4 3 8 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB62124.1 - 5e-07 29.4 23.9 5.6e-05 22.7 6.9 6.4 4 1 3 7 7 7 4 Leucine-rich repeat LRR_2 PF07723.13 EQB62124.1 - 0.0039 17.8 1.2 21 6.0 0.2 5.5 4 0 0 4 4 4 1 Leucine Rich Repeat Sec63 PF02889.16 EQB62125.1 - 0.00011 21.5 1.0 0.00011 21.5 1.0 1.7 2 0 0 2 2 2 1 Sec63 Brl domain DnaJ PF00226.31 EQB62125.1 - 0.00047 20.2 4.5 0.0011 19.1 4.5 1.6 1 0 0 1 1 1 1 DnaJ domain zf-LITAF-like PF10601.9 EQB62125.1 - 0.041 14.1 0.5 1 9.7 0.1 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain UCH PF00443.29 EQB62128.1 - 1.2e-11 44.6 14.8 1.2e-10 41.3 14.8 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 EQB62129.1 - 5.3e-13 49.1 10.6 5e-12 45.9 10.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RVT PF13966.6 EQB62130.1 - 0.0016 19.1 0.2 0.0055 17.4 0.2 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3797 PF12677.7 EQB62131.1 - 0.023 14.6 1.9 0.023 14.6 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) ATC_hydrolase PF14196.6 EQB62132.1 - 0.029 15.1 0.4 0.042 14.6 0.4 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase CLIP_SPH_mas PF18398.1 EQB62132.1 - 0.26 11.7 0.6 0.39 11.2 0.6 1.3 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade ABC2_membrane_3 PF12698.7 EQB62135.1 - 0.0039 16.3 2.5 0.0044 16.2 2.5 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein CC190 PF15768.5 EQB62142.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 FAD_SOX PF18371.1 EQB62143.1 - 0.043 14.2 0.0 0.064 13.6 0.0 1.4 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase HECW_N PF16562.5 EQB62144.1 - 0.14 12.0 0.6 0.25 11.1 0.2 1.6 1 1 1 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 DUF5089 PF17002.5 EQB62145.1 - 5.3e-12 46.0 10.9 5.3e-12 46.0 10.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) DUF4337 PF14235.6 EQB62145.1 - 8.6 6.4 10.3 4.9 7.2 8.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) HECT PF00632.25 EQB62147.1 - 1.6e-09 37.7 1.5 2.1e-09 37.3 1.5 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2179 PF10035.9 EQB62149.1 - 0.14 11.9 2.0 0.86 9.4 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) GCP_N_terminal PF17681.1 EQB62150.1 - 9.6e-11 41.9 6.3 1.3e-10 41.4 6.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4990 PF16380.5 EQB62151.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function RUN PF02759.19 EQB62151.1 - 0.13 12.2 0.5 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 RUN domain Fcf1 PF04900.12 EQB62152.1 - 5.5e-29 100.5 0.0 8e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EQB62152.1 - 9.4e-11 42.0 0.0 1.1e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 PIN like domain dCMP_cyt_deam_1 PF00383.23 EQB62154.1 - 1.5e-15 56.9 0.2 2e-15 56.5 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EQB62154.1 - 1.1e-13 51.5 0.1 1.3e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EQB62154.1 - 0.00017 21.2 1.3 0.047 13.3 0.3 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF1492 PF07374.11 EQB62156.1 - 0.11 12.6 9.3 0.1 12.7 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) CLASP_N PF12348.8 EQB62157.1 - 2.6e-06 27.2 2.3 3.3e-06 26.8 0.9 1.7 1 1 0 1 1 1 1 CLASP N terminal TraI_2_C PF07515.11 EQB62157.1 - 0.026 14.5 0.7 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term SOGA PF11365.8 EQB62157.1 - 0.32 12.2 3.2 0.73 11.0 0.7 2.7 2 1 1 3 3 3 0 Protein SOGA MtrB PF05440.12 EQB62158.1 - 0.15 12.5 0.2 5.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF4976 PF16347.5 EQB62158.1 - 0.17 12.2 3.6 0.52 10.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) BRICHOS PF04089.14 EQB62158.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.0 2 1 1 3 3 3 0 BRICHOS domain DEAD PF00270.29 EQB62159.1 - 2e-20 73.3 0.0 2.5e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EQB62159.1 - 6.1e-08 32.8 0.9 6.7e-08 32.7 0.9 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4217 PF13959.6 EQB62159.1 - 0.0028 17.9 0.9 0.0047 17.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EQB62160.1 - 2.2e-14 53.7 2.0 3.5e-14 53.1 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 EQB62160.1 - 3.4e-11 43.4 0.0 5.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EQB62160.1 - 0.026 14.3 1.7 0.051 13.4 0.7 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EQB62160.1 - 0.089 13.2 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold UPF0223 PF05256.12 EQB62160.1 - 0.26 11.6 4.0 0.19 12.1 0.3 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0223) NusG_add PF18298.1 EQB62160.1 - 0.29 11.4 3.8 9.1 6.6 0.2 2.8 2 0 0 2 2 2 0 NusG additional domain RNF220 PF15926.5 EQB62161.1 - 0.15 11.7 6.5 0.027 14.1 1.9 2.0 1 1 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Tyrosinase PF00264.20 EQB62161.1 - 0.43 10.8 3.3 0.54 10.5 3.3 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase MOZ_SAS PF01853.18 EQB62162.1 - 1.2e-72 243.3 1.2 2e-72 242.6 1.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EQB62162.1 - 9.5e-23 79.6 4.0 2.1e-22 78.5 4.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EQB62162.1 - 3e-18 65.5 0.4 3e-18 65.5 0.4 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EQB62162.1 - 0.035 14.5 0.0 0.095 13.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PH_BEACH PF14844.6 EQB62162.1 - 0.037 14.1 1.8 0.37 10.9 0.5 2.4 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH NTP_transferase PF00483.23 EQB62163.1 - 2.2e-07 30.7 0.1 9.2e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase DUF4806 PF16064.5 EQB62163.1 - 0.0086 16.4 1.0 0.033 14.5 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4806) TraF PF13728.6 EQB62164.1 - 0.00038 20.3 0.4 0.0091 15.8 0.0 2.1 2 0 0 2 2 2 1 F plasmid transfer operon protein BsuBI_PstI_RE PF06616.11 EQB62164.1 - 0.019 14.2 0.3 0.038 13.3 0.3 1.5 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain zf-RVT PF13966.6 EQB62164.1 - 0.037 14.7 0.3 0.08 13.7 0.3 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glutaredoxin PF00462.24 EQB62164.1 - 0.038 14.2 0.2 0.15 12.3 0.2 2.0 1 0 0 1 1 1 0 Glutaredoxin HSDR_N_2 PF13588.6 EQB62164.1 - 0.094 12.7 3.0 0.16 12.0 1.9 1.9 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) PepSY_like PF11396.8 EQB62164.1 - 1.3 9.6 5.2 43 4.8 0.0 2.5 2 1 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Coat_X PF07552.11 EQB62165.1 - 0.0042 16.9 1.4 0.013 15.3 1.4 1.9 1 0 0 1 1 1 1 Spore Coat Protein X and V domain Peptidase_C50 PF03568.17 EQB62166.1 - 3.5e-23 82.4 7.8 5.2e-19 68.6 0.1 3.0 1 1 1 2 2 2 2 Peptidase family C50 TPR_1 PF00515.28 EQB62166.1 - 0.0075 16.0 0.6 0.019 14.7 0.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat COG5 PF10392.9 EQB62166.1 - 1.2 9.3 7.9 0.67 10.1 4.4 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 ParA PF10609.9 EQB62167.1 - 1e-33 116.8 0.0 1.1e-33 116.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_31 PF13614.6 EQB62167.1 - 9.2e-06 25.7 0.9 1.4e-05 25.1 0.9 1.3 1 0 0 1 1 1 1 AAA domain DUF5126 PF17166.4 EQB62167.1 - 0.007 16.2 0.1 0.4 10.6 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5126) BHD_3 PF10405.9 EQB62168.1 - 2.6e-08 34.1 0.1 8.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EQB62168.1 - 6.4e-08 32.3 0.1 2.6e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 PAP_fibrillin PF04755.12 EQB62170.1 - 0.14 12.1 6.5 0.15 12.0 6.5 1.1 1 0 0 1 1 1 0 PAP_fibrillin UCH PF00443.29 EQB62171.1 - 1.6e-33 116.3 7.4 3.2e-33 115.3 7.4 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3725 PF12523.8 EQB62171.1 - 0.021 15.1 2.9 0.042 14.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) HalOD2 PF18547.1 EQB62171.1 - 0.031 14.2 1.1 0.081 12.8 0.2 2.1 2 0 0 2 2 2 0 Halobacterial output domain 2 C1_1 PF00130.22 EQB62171.1 - 2.5 8.0 8.8 5.7 6.9 0.1 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TMF_TATA_bd PF12325.8 EQB62172.1 - 0.017 15.4 15.6 2.1 8.6 0.1 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EQB62172.1 - 0.14 11.4 7.1 0.18 11.1 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cas_DxTHG PF09455.10 EQB62172.1 - 0.96 9.0 22.1 1.1 8.7 22.1 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family M_domain PF12938.7 EQB62172.1 - 4.1 7.1 6.9 4.3 7.1 4.9 1.8 1 1 1 2 2 2 0 M domain of GW182 Exonuc_VII_L PF02601.15 EQB62172.1 - 4.9 6.6 11.7 5.4 6.5 11.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SMC_N PF02463.19 EQB62173.1 - 5.1e-10 39.2 0.0 5.1e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Minor_capsid_3 PF12691.7 EQB62175.1 - 0.016 15.6 0.1 0.027 14.9 0.1 1.3 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage zf-ZPR1 PF03367.13 EQB62175.1 - 0.035 14.0 0.2 0.043 13.7 0.2 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain MM_CoA_mutase PF01642.22 EQB62175.1 - 0.17 10.4 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase tRNA-synt_His PF13393.6 EQB62177.1 - 5.8e-18 65.2 0.0 7.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EQB62177.1 - 2.2e-06 27.7 0.1 4.5e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EQB62177.1 - 8.9e-05 22.1 0.4 0.00013 21.6 0.4 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 EQB62178.1 - 3.8e-06 26.4 0.0 4.4e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase ADK PF00406.22 EQB62183.1 - 6.8e-24 84.7 1.8 2.2e-16 60.3 0.8 2.4 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EQB62183.1 - 8.2e-12 45.7 0.4 8.2e-05 23.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 EQB62183.1 - 4.2e-09 37.0 0.7 6.4e-05 23.5 0.1 2.8 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 EQB62183.1 - 1.3e-05 25.4 0.0 0.12 12.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain dNK PF01712.19 EQB62183.1 - 0.00081 19.3 1.8 0.0014 18.5 1.8 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 EQB62183.1 - 0.025 14.2 0.2 0.058 13.1 0.2 1.6 1 0 0 1 1 1 0 Thymidylate kinase RuvB_N PF05496.12 EQB62183.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EQB62183.1 - 0.068 13.6 0.6 0.38 11.2 0.1 2.4 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EQB62183.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF5094 PF17015.5 EQB62185.1 - 8.9e-39 133.4 22.4 6.1e-37 127.4 22.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5094) PH PF00169.29 EQB62186.1 - 2.1e-06 28.2 0.3 2.1e-06 28.2 0.3 2.5 3 1 0 3 3 3 1 PH domain SARAF PF06682.12 EQB62186.1 - 0.13 11.9 3.2 0.19 11.3 3.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis tRNA-synt_His PF13393.6 EQB62187.1 - 0.00054 19.3 0.0 0.00061 19.1 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Piwi PF02171.17 EQB62188.1 - 2.1e-71 240.6 2.1 3.1e-68 230.3 0.4 2.9 2 1 1 3 3 3 2 Piwi domain SieB PF14163.6 EQB62188.1 - 0.097 12.2 0.6 0.2 11.1 0.3 1.7 1 1 0 1 1 1 0 Super-infection exclusion protein B ArgoN PF16486.5 EQB62189.1 - 5.9e-06 26.9 0.1 1e-05 26.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EQB62189.1 - 0.02 14.5 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 1 domain WD40 PF00400.32 EQB62191.1 - 3.5e-34 116.3 18.7 8e-11 42.3 0.4 7.4 7 1 1 8 8 8 5 WD domain, G-beta repeat WD40_like PF17005.5 EQB62191.1 - 1.2e-07 31.4 6.7 4.5e-05 22.9 5.3 4.0 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EQB62191.1 - 3.6e-06 27.2 0.1 0.0065 16.7 0.0 4.7 2 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EQB62191.1 - 0.0011 18.3 0.1 0.0076 15.6 0.0 2.0 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5462 PF17547.2 EQB62192.1 - 0.028 13.8 0.1 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5462) C2 PF00168.30 EQB62193.1 - 2.5e-16 59.8 0.6 1e-13 51.5 0.1 3.0 3 0 0 3 3 3 2 C2 domain DUF4819 PF16090.5 EQB62193.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) DUF3357 PF11837.8 EQB62196.1 - 0.02 15.3 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) TPPK_C PF12555.8 EQB62196.1 - 0.022 14.8 2.1 0.031 14.3 2.1 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF4834 PF16118.5 EQB62196.1 - 0.039 14.9 0.0 0.059 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SecG PF03840.14 EQB62196.1 - 0.04 14.0 1.9 0.062 13.4 1.9 1.5 1 1 0 1 1 1 0 Preprotein translocase SecG subunit FAM209 PF15206.6 EQB62196.1 - 0.09 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 FAM209 family DUF2628 PF10947.8 EQB62196.1 - 0.1 13.0 0.7 0.13 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) CDK2AP PF09806.9 EQB62196.1 - 0.1 12.7 1.4 0.13 12.4 1.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF929 PF06053.11 EQB62196.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF929) MRAP PF15183.6 EQB62196.1 - 0.2 11.6 2.5 0.68 9.9 2.5 1.8 1 1 0 1 1 1 0 Melanocortin-2 receptor accessory protein family LRR19-TM PF15176.6 EQB62196.1 - 0.3 11.1 1.3 0.37 10.8 0.1 1.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain SP_C-Propep PF08999.10 EQB62196.1 - 0.36 10.6 2.4 0.58 10.0 2.4 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Orf78 PF06024.12 EQB62196.1 - 0.48 10.8 1.8 2.4 8.5 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Synaptobrevin PF00957.21 EQB62196.1 - 2.4 8.0 4.5 0.79 9.6 0.4 1.9 2 0 0 2 2 2 0 Synaptobrevin FtsX_ECD PF18075.1 EQB62198.1 - 0.22 12.2 0.0 0.42 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsX extracellular domain Arabinose_trans PF04602.12 EQB62198.1 - 0.37 9.6 0.0 0.51 9.1 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein RRS1 PF04939.12 EQB62199.1 - 4.7e-18 65.6 1.9 5.5e-18 65.4 1.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) vATP-synt_AC39 PF01992.16 EQB62200.1 - 1.2e-28 100.6 16.5 1.4e-22 80.6 9.6 2.1 2 0 0 2 2 2 2 ATP synthase (C/AC39) subunit GSHPx PF00255.19 EQB62202.1 - 3.6e-06 26.5 0.2 1.8e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione peroxidase Lectin_leg-like PF03388.13 EQB62203.1 - 6.5e-07 28.9 2.0 7.5e-07 28.7 1.4 1.5 1 1 1 2 2 2 1 Legume-like lectin family DUF4247 PF14042.6 EQB62203.1 - 0.058 14.1 0.1 0.13 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4247) Lectin_legB PF00139.19 EQB62203.1 - 0.13 11.7 3.7 0.22 11.0 2.0 1.9 1 1 1 2 2 2 0 Legume lectin domain Chromadorea_ALT PF05535.12 EQB62204.1 - 0.075 13.2 0.4 0.25 11.6 0.4 1.8 1 0 0 1 1 1 0 Chromadorea ALT protein PrpR_N PF06506.11 EQB62207.1 - 0.11 12.1 0.3 0.21 11.1 0.3 1.4 1 0 0 1 1 1 0 Propionate catabolism activator Asparaginase PF00710.20 EQB62208.1 - 1.5e-55 187.7 0.0 2.1e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EQB62208.1 - 2.2e-22 79.4 0.0 6.1e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DUF4990 PF16380.5 EQB62210.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function RUN PF02759.19 EQB62210.1 - 0.13 12.2 0.5 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 RUN domain GCP_N_terminal PF17681.1 EQB62212.1 - 9.6e-11 41.9 6.3 1.3e-10 41.4 6.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Peptidase_C65 PF10275.9 EQB62214.1 - 5.3e-20 71.9 11.7 1.7e-18 67.0 11.7 2.1 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EQB62214.1 - 1.4e-06 28.8 0.3 1.5e-05 25.5 0.3 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease RNR_N PF08343.10 EQB62215.1 - 0.0023 17.9 1.0 0.0078 16.2 1.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase N-terminal Ribosomal_L1 PF00687.21 EQB62216.1 - 5e-18 65.6 3.4 6.8e-12 45.5 0.2 2.0 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family DUF1297 PF06973.12 EQB62216.1 - 0.03 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) zf-C2H2 PF00096.26 EQB62218.1 - 6.1e-06 26.4 5.7 0.00025 21.3 2.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EQB62218.1 - 0.00024 21.7 5.1 0.023 15.5 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EQB62218.1 - 0.00097 19.5 1.1 0.00097 19.5 1.1 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 EQB62218.1 - 0.0012 19.1 0.8 0.034 14.5 0.8 2.0 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 EQB62218.1 - 0.014 15.8 1.8 0.036 14.5 0.2 2.3 2 1 0 2 2 2 0 Zinc-finger of C2H2 type LRR_1 PF00560.33 EQB62219.1 - 0.00098 19.4 5.0 2.3 9.1 0.4 5.0 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 EQB62219.1 - 0.0097 15.6 4.8 0.14 11.9 4.3 3.1 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EQB62219.1 - 0.05 14.0 12.4 0.16 12.5 3.6 4.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Nrap PF03813.14 EQB62220.1 - 0.022 14.8 3.8 0.032 14.3 3.8 1.2 1 0 0 1 1 1 0 Nrap protein domain 1 Prefoldin_2 PF01920.20 EQB62221.1 - 0.0049 16.8 7.9 0.0049 16.8 7.9 4.0 1 1 2 3 3 3 1 Prefoldin subunit KASH_CCD PF14662.6 EQB62221.1 - 0.015 15.2 30.5 0.29 10.9 23.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 EQB62221.1 - 0.026 14.4 0.3 0.026 14.4 0.3 4.9 4 1 2 6 6 6 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 EQB62221.1 - 0.04 14.1 1.0 0.04 14.1 1.0 4.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper Leu_zip PF15294.6 EQB62221.1 - 0.068 12.7 27.9 4.9 6.6 0.4 2.9 1 1 2 3 3 3 0 Leucine zipper SOGA PF11365.8 EQB62221.1 - 0.18 13.0 22.5 4.9 8.4 1.1 3.7 1 1 1 3 3 3 0 Protein SOGA ADIP PF11559.8 EQB62221.1 - 0.27 11.3 29.0 1.2 9.2 5.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 EQB62221.1 - 1.2 9.6 23.8 1.4 9.4 1.7 4.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 EQB62221.1 - 1.6 8.9 29.8 0.11 12.6 1.7 4.4 1 1 2 4 4 4 0 bZIP transcription factor Fungal_TACC PF12709.7 EQB62221.1 - 1.8 9.0 27.2 0.75 10.3 4.0 3.4 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 EQB62221.1 - 1.8 8.4 28.5 1.1 9.1 3.0 4.1 2 1 2 4 4 4 0 Septum formation initiator Uso1_p115_C PF04871.13 EQB62221.1 - 2.4 8.5 22.5 1.2 9.6 6.9 2.7 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cnn_1N PF07989.11 EQB62221.1 - 2.8 8.2 30.2 0.12 12.6 12.0 3.0 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 EQB62221.1 - 3 7.9 30.5 0.53 10.3 18.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1192 PF06698.11 EQB62221.1 - 4.1 7.5 8.5 13 6.0 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) PACT_coil_coil PF10495.9 EQB62221.1 - 6.1 7.5 9.5 5.4 7.7 1.0 3.3 1 1 3 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Exonuc_VII_L PF02601.15 EQB62221.1 - 6.7 6.2 14.4 8.8 5.8 14.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phlebovirus_NSM PF07246.11 EQB62221.1 - 9.9 5.4 21.1 0.047 13.1 3.1 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M AAA_2 PF07724.14 EQB62222.1 - 1.5e-42 145.6 0.3 1.1e-39 136.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EQB62222.1 - 3.5e-28 97.6 1.7 3.5e-28 97.6 1.7 2.6 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 EQB62222.1 - 1.2e-25 90.4 0.2 2.4e-13 50.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EQB62222.1 - 2.5e-15 56.7 0.4 1.1e-10 41.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EQB62222.1 - 1.6e-13 51.4 0.7 0.0022 18.4 0.0 5.3 4 1 1 5 5 5 2 AAA ATPase domain ClpB_D2-small PF10431.9 EQB62222.1 - 7.2e-12 45.2 0.4 7.3e-11 42.0 0.1 3.1 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA_14 PF13173.6 EQB62222.1 - 1.9e-08 34.4 1.0 0.081 13.0 0.0 4.2 4 1 0 4 4 3 2 AAA domain Sigma54_activat PF00158.26 EQB62222.1 - 2.2e-08 34.0 0.3 6.8e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EQB62222.1 - 7.7e-08 32.3 0.4 0.0016 18.2 0.0 3.1 3 1 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EQB62222.1 - 6.9e-07 28.9 1.9 0.021 14.2 0.1 3.9 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI Clp_N PF02861.20 EQB62222.1 - 1.4e-06 28.3 0.0 1.7e-05 24.8 0.1 2.6 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 EQB62222.1 - 3.3e-06 26.7 0.1 0.083 12.4 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 EQB62222.1 - 3.4e-06 26.9 3.3 0.035 13.8 0.0 4.1 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EQB62222.1 - 4.1e-06 26.8 0.2 0.0051 16.7 0.1 2.5 2 0 0 2 2 2 1 NACHT domain TniB PF05621.11 EQB62222.1 - 4.6e-06 26.2 0.1 0.055 12.9 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 EQB62222.1 - 4.9e-06 26.9 2.0 0.17 12.1 0.3 3.9 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EQB62222.1 - 5.1e-06 25.9 1.9 0.0097 15.2 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin RNA_helicase PF00910.22 EQB62222.1 - 3.8e-05 24.0 0.3 0.84 10.0 0.0 3.4 3 0 0 3 3 3 2 RNA helicase TsaE PF02367.17 EQB62222.1 - 9.6e-05 22.4 0.3 0.57 10.2 0.1 2.9 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EQB62222.1 - 0.00016 21.6 0.3 0.14 12.1 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_33 PF13671.6 EQB62222.1 - 0.00019 21.6 0.4 0.61 10.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 EQB62222.1 - 0.00024 21.3 0.1 0.63 10.3 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EQB62222.1 - 0.00027 21.5 1.8 0.084 13.4 0.0 3.6 3 1 0 3 3 2 1 AAA domain ParA PF10609.9 EQB62222.1 - 0.00031 20.3 0.6 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 EQB62222.1 - 0.00038 20.1 0.6 0.12 11.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EQB62222.1 - 0.00055 19.7 0.2 0.23 11.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EQB62222.1 - 0.0013 18.7 1.6 2.1 8.3 0.3 3.6 2 1 0 3 3 3 1 NTPase AAA_17 PF13207.6 EQB62222.1 - 0.0025 18.3 0.1 5 7.5 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EQB62222.1 - 0.003 17.3 0.1 0.58 9.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EQB62222.1 - 0.0043 16.2 0.9 1.8 7.7 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ResIII PF04851.15 EQB62222.1 - 0.0058 16.6 5.9 0.16 11.9 0.0 3.9 4 1 0 4 4 3 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 EQB62222.1 - 0.0065 16.3 0.5 0.88 9.4 0.0 3.2 3 0 0 3 3 2 1 Bacterial dnaA protein NB-ARC PF00931.22 EQB62222.1 - 0.01 15.0 2.3 1.2 8.3 0.4 3.2 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.22 EQB62222.1 - 0.021 14.5 0.7 3.9 7.0 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.6 EQB62222.1 - 0.021 14.6 0.0 0.28 11.0 0.0 2.7 3 0 0 3 3 2 0 DNA polymerase III, delta subunit T2SSE PF00437.20 EQB62222.1 - 0.022 13.8 2.0 0.3 10.1 0.0 2.7 2 1 0 2 2 2 0 Type II/IV secretion system protein CbiA PF01656.23 EQB62222.1 - 0.025 14.6 2.3 5.6 7.0 0.4 3.3 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 EQB62222.1 - 0.026 14.3 0.3 5.4 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain PhoH PF02562.16 EQB62222.1 - 0.027 13.9 0.3 0.69 9.3 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 EQB62222.1 - 0.03 14.4 0.1 0.03 14.4 0.1 4.5 4 1 1 5 5 4 0 Helicase HerA, central domain ATPase_2 PF01637.18 EQB62222.1 - 0.033 14.1 0.3 0.033 14.1 0.3 5.0 5 1 1 6 6 4 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EQB62222.1 - 0.035 14.0 0.1 13 5.7 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MAD PF05557.13 EQB62222.1 - 0.035 12.5 10.6 0.064 11.6 10.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_19 PF13245.6 EQB62222.1 - 0.037 14.4 3.8 4.1 7.7 1.3 3.5 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EQB62222.1 - 0.049 14.2 6.0 1.1 9.8 0.0 3.5 4 0 0 4 4 2 0 ABC transporter MMR_HSR1 PF01926.23 EQB62222.1 - 0.053 13.6 0.5 2 8.5 0.2 3.3 3 0 0 3 3 2 0 50S ribosome-binding GTPase Torsin PF06309.11 EQB62222.1 - 0.093 12.8 0.0 1.5 8.9 0.0 2.7 3 0 0 3 3 2 0 Torsin TIP49 PF06068.13 EQB62222.1 - 0.1 11.8 14.3 0.16 11.2 0.0 3.4 3 1 1 4 4 3 0 TIP49 P-loop domain AAA_28 PF13521.6 EQB62222.1 - 0.15 12.3 0.1 4.5 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EQB62222.1 - 0.18 10.7 3.5 4.2 6.2 0.0 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ArsA_ATPase PF02374.15 EQB62222.1 - 1.9 7.6 9.2 6.1 5.9 0.0 3.5 4 0 0 4 4 4 0 Anion-transporting ATPase Ribonuclease_3 PF00636.26 EQB62223.1 - 5e-16 59.2 0.1 7.4e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EQB62223.1 - 6.4e-10 39.3 0.0 7.6e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease-III-like Dicer_dimer PF03368.14 EQB62224.1 - 3.6e-08 33.5 0.0 6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Dicer dimerisation domain KxDL PF10241.9 EQB62224.1 - 0.068 13.5 1.6 10 6.5 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein Med9 PF07544.13 EQB62224.1 - 0.099 12.7 0.5 0.2 11.7 0.5 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ESP PF16590.5 EQB62225.1 - 4.2 7.7 8.7 2 8.7 2.0 2.5 2 1 0 2 2 2 0 Exocrine gland-secreting peptide DFRP_C PF16543.5 EQB62226.1 - 8.2e-12 45.5 2.0 8.2e-12 45.5 2.0 2.2 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EQB62226.1 - 0.00047 20.8 2.1 0.0047 17.6 1.5 2.3 2 0 0 2 2 2 1 Torus domain ACCA PF03255.14 EQB62226.1 - 0.0087 15.9 0.9 0.02 14.8 0.9 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit zf-CCCH_4 PF18044.1 EQB62226.1 - 0.014 15.2 2.6 0.014 15.2 2.6 2.3 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 EQB62226.1 - 0.087 12.8 0.7 0.087 12.8 0.7 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1359 PF07097.11 EQB62226.1 - 0.69 10.2 7.3 2.4 8.4 7.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) MMTV_SAg PF01054.17 EQB62226.1 - 2 8.0 7.3 0.63 9.6 4.1 1.8 1 1 1 2 2 2 0 Mouse mammary tumour virus superantigen Mei5_like PF17021.5 EQB62227.1 - 1.6e-39 134.6 12.9 1.7e-39 134.5 12.9 1.0 1 0 0 1 1 1 1 Putative double-strand recombination repair-like Cyclin_N PF00134.23 EQB62228.1 - 6.1e-22 77.7 0.2 1.2e-21 76.8 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3234 PF11572.8 EQB62228.1 - 0.016 15.3 0.0 0.061 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3234) Pro_3_hydrox_C PF05373.11 EQB62229.1 - 0.086 12.9 1.1 7.1 6.8 0.4 2.4 1 1 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal FoP_duplication PF13865.6 EQB62230.1 - 7.7e-05 23.2 6.2 7.7e-05 23.2 6.2 2.6 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 UL16 PF17622.2 EQB62231.1 - 0.0005 19.8 0.3 0.0005 19.8 0.3 1.6 2 0 0 2 2 2 1 Viral unique long protein 16 DUF1240 PF06836.12 EQB62231.1 - 1.2 9.7 19.6 0.32 11.6 5.3 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1240) Arm-DNA-bind_2 PF12167.8 EQB62232.1 - 0.039 13.9 4.4 0.41 10.6 0.1 2.9 3 0 0 3 3 3 0 Arm DNA-binding domain MsyB PF13984.6 EQB62232.1 - 0.061 13.6 0.7 0.11 12.8 0.7 1.4 1 0 0 1 1 1 0 MsyB protein Acyl_CoA_thio PF02551.15 EQB62233.1 - 1.8e-07 31.0 0.0 2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EQB62233.1 - 3.4e-07 30.8 0.0 3.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2996 PF11210.8 EQB62233.1 - 0.064 13.7 0.3 0.2 12.1 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2996) HECT PF00632.25 EQB62234.1 - 1.1e-53 182.8 8.7 1.5e-53 182.3 8.7 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Coat_X PF07552.11 EQB62235.1 - 0.0045 16.8 1.4 0.013 15.3 1.4 1.8 1 0 0 1 1 1 1 Spore Coat Protein X and V domain Nucleolin_bd PF16725.5 EQB62238.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Nucleolin binding domain zf-C2H2_4 PF13894.6 EQB62238.1 - 9.9 7.3 8.1 4.6 8.3 0.4 3.2 1 1 2 3 3 3 0 C2H2-type zinc finger EamA PF00892.20 EQB62239.1 - 2.7e-05 24.4 18.3 2.7e-05 24.4 18.3 2.9 3 0 0 3 3 3 2 EamA-like transporter family Peptidase_S8 PF00082.22 EQB62240.1 - 9.6e-12 44.8 1.3 1.1e-10 41.2 0.5 2.6 2 1 0 2 2 2 1 Subtilase family Ni_hydr_CYTB PF01292.20 EQB62240.1 - 0.017 14.7 0.5 0.028 14.0 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 SecY PF00344.20 EQB62240.1 - 0.25 10.6 5.0 0.16 11.2 0.5 2.1 2 0 0 2 2 2 0 SecY translocase TNFR_16_TM PF18422.1 EQB62240.1 - 0.3 11.1 2.6 0.79 9.7 2.6 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain FeoB_associated PF12669.7 EQB62240.1 - 0.99 9.9 4.8 2.7 8.5 4.8 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein AhpC-TSA PF00578.21 EQB62241.1 - 1.6e-25 89.4 0.1 2e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EQB62241.1 - 1e-11 44.8 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EQB62241.1 - 0.0039 17.1 0.1 0.0066 16.4 0.1 1.3 1 0 0 1 1 1 1 SCO1/SenC U71 PF17474.2 EQB62241.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Tegument protein UL11 homolog Ribosomal_L3 PF00297.22 EQB62242.1 - 5.8e-91 305.2 4.9 2.2e-64 217.8 1.5 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 Pal1 PF08316.11 EQB62242.1 - 0.13 13.0 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 Pal1 cell morphology protein IMP_cyclohyd PF07826.11 EQB62244.1 - 0.052 13.2 0.2 0.092 12.3 0.2 1.3 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Nup160 PF11715.8 EQB62244.1 - 0.081 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Kelch_6 PF13964.6 EQB62244.1 - 0.14 12.5 0.1 0.47 10.8 0.1 1.9 1 0 0 1 1 1 0 Kelch motif SH3_14 PF18343.1 EQB62244.1 - 0.14 12.2 1.0 0.76 9.9 0.4 2.3 2 0 0 2 2 2 0 Dda helicase SH3 domain Creb_binding PF09030.10 EQB62244.1 - 0.25 12.1 0.1 0.44 11.3 0.1 1.3 1 0 0 1 1 1 0 Creb binding Homeodomain PF00046.29 EQB62246.1 - 2.7e-19 68.8 1.8 2.7e-19 68.8 1.8 1.7 2 0 0 2 2 2 1 Homeodomain Pectate_lyase_3 PF12708.7 EQB62252.1 - 0.079 12.8 2.2 0.33 10.8 1.1 1.8 1 1 1 2 2 2 0 Pectate lyase superfamily protein ProRS-C_1 PF09180.11 EQB62257.1 - 2.8e-20 72.3 4.9 6e-20 71.2 3.2 2.5 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EQB62257.1 - 6.1e-19 68.7 0.0 6.1e-19 68.7 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ERCC4 PF02732.15 EQB62257.1 - 2.9e-17 63.3 1.3 2.9e-17 63.3 1.3 3.3 3 1 1 4 4 4 1 ERCC4 domain HGTP_anticodon PF03129.20 EQB62257.1 - 2.2e-11 43.7 0.4 8.4e-11 41.9 0.4 2.1 1 0 0 1 1 1 1 Anticodon binding domain RIBIOP_C PF04950.12 EQB62258.1 - 1.5e-40 139.4 3.1 2.6e-40 138.7 3.1 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Pkinase PF00069.25 EQB62259.1 - 9.4e-23 80.9 0.0 3.1e-13 49.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EQB62259.1 - 4.1e-09 36.1 0.0 0.00063 19.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase BING4CT PF08149.11 EQB62260.1 - 1.2e-13 50.7 0.3 7.7e-10 38.4 0.0 4.0 3 1 1 4 4 4 2 BING4CT (NUC141) domain ubiquitin PF00240.23 EQB62260.1 - 3.7e-05 23.4 0.3 0.00013 21.7 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin family ANAPC4_WD40 PF12894.7 EQB62260.1 - 0.00028 21.1 0.2 1.9 8.8 0.2 3.1 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2407 PF10302.9 EQB62260.1 - 0.022 15.3 0.0 0.059 13.9 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WD40 PF00400.32 EQB62260.1 - 0.028 15.3 0.5 3 8.9 0.2 3.2 2 1 0 2 2 2 0 WD domain, G-beta repeat Ubiquitin_4 PF18036.1 EQB62260.1 - 0.053 13.6 0.9 0.64 10.1 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain UN_NPL4 PF11543.8 EQB62260.1 - 0.51 10.9 5.4 3.8 8.1 0.2 3.3 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 WD40 PF00400.32 EQB62261.1 - 8e-25 86.6 13.3 6.5e-05 23.6 0.0 7.2 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EQB62261.1 - 1e-12 48.1 0.5 0.026 14.8 0.0 5.1 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EQB62261.1 - 5.5e-09 36.2 0.7 0.0003 20.7 0.1 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4606 PF15379.6 EQB62263.1 - 0.14 12.4 3.4 0.11 12.8 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) LRR_8 PF13855.6 EQB62264.1 - 7.4e-10 38.4 34.9 0.0003 20.5 1.6 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EQB62264.1 - 1.2e-09 38.2 44.3 9.9e-05 22.6 2.6 6.4 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EQB62264.1 - 0.00033 20.2 12.2 0.019 14.5 3.6 2.5 1 1 1 2 2 2 2 Leucine-rich repeat NBD94 PF16830.5 EQB62264.1 - 1.9 8.9 11.7 3.2 8.2 1.7 4.2 1 1 2 3 3 3 0 Nucleotide-Binding Domain 94 of RH RVT_1 PF00078.27 EQB62266.1 - 4.9e-15 55.6 0.0 6.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EQB62267.1 - 6.2e-18 65.1 0.0 9.4e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EQB62267.1 - 4.2e-05 23.2 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Imm64 PF15600.6 EQB62267.1 - 0.032 13.9 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 64 AMP-binding_C PF13193.6 EQB62268.1 - 6.3e-16 59.1 4.7 9.3e-08 32.9 0.8 2.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EQB62268.1 - 1.3e-05 24.0 0.4 2.7e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme MxiM PF11441.8 EQB62268.1 - 0.0037 17.5 3.0 0.02 15.2 2.5 2.2 1 1 1 2 2 2 1 Pilot protein MxiM ETM PF17577.2 EQB62268.1 - 0.077 13.6 3.3 0.12 12.9 2.8 1.6 1 1 0 1 1 1 0 ECORI-T site Homeodomain PF00046.29 EQB62269.1 - 5.3e-13 48.6 3.4 6.4e-13 48.3 1.4 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EQB62269.1 - 1.4e-12 47.3 0.2 3.6e-12 46.0 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Herpes_UL92 PF03048.14 EQB62269.1 - 0.01 15.6 3.8 0.018 14.9 2.5 1.8 1 1 0 2 2 2 0 UL92 family YdaS_antitoxin PF15943.5 EQB62269.1 - 0.066 13.1 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homez PF11569.8 EQB62269.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez CDC45 PF02724.14 EQB62274.1 - 0.078 11.3 4.9 0.081 11.2 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EQB62274.1 - 0.079 11.7 8.1 0.081 11.7 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 EQB62274.1 - 0.088 11.6 5.0 0.11 11.2 5.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 EQB62274.1 - 0.11 10.7 9.7 0.11 10.7 9.7 1.0 1 0 0 1 1 1 0 Nop14-like family Striatin PF08232.12 EQB62274.1 - 3.5 8.2 6.7 5.2 7.6 6.7 1.4 1 0 0 1 1 1 0 Striatin family LRR_8 PF13855.6 EQB62275.1 - 1.3e-21 76.1 85.5 4.9e-08 32.6 11.1 6.7 2 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EQB62275.1 - 3e-13 49.7 66.6 2.1e-06 27.9 13.5 7.2 4 1 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB62275.1 - 0.099 13.2 53.2 0.13 12.9 1.1 9.6 6 3 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EQB62275.1 - 0.14 12.3 0.5 0.14 12.3 0.5 8.0 8 1 0 8 8 8 0 Leucine Rich repeat Neur_chan_memb PF02932.16 EQB62276.1 - 0.002 18.2 1.1 0.0031 17.6 1.1 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.10 EQB62276.1 - 0.015 13.5 8.6 0.11 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO CDC45 PF02724.14 EQB62276.1 - 0.018 13.4 9.1 0.021 13.1 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3328 PF11807.8 EQB62276.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3391 PF11871.8 EQB62276.1 - 6 7.4 8.5 12 6.4 8.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) EOS1 PF12326.8 EQB62277.1 - 6.7 6.6 6.4 12 5.8 6.4 1.5 1 1 0 1 1 1 0 N-glycosylation protein TFIID_20kDa PF03847.13 EQB62278.1 - 0.00029 21.3 1.2 0.00043 20.7 1.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID_30kDa PF03540.13 EQB62278.1 - 0.0051 16.7 0.0 0.0088 16.0 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TFIID-31kDa PF02291.15 EQB62278.1 - 0.0086 16.1 0.0 0.0099 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 EQB62278.1 - 0.031 14.3 0.1 0.036 14.1 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PyrI PF01948.18 EQB62278.1 - 0.048 13.9 2.0 0.069 13.4 0.9 1.8 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Myosin_head PF00063.21 EQB62279.1 - 2.5e-76 257.4 11.3 3.1e-76 257.1 11.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EQB62279.1 - 0.01 15.6 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EQB62279.1 - 0.022 15.0 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EQB62279.1 - 0.1 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EQB62279.1 - 0.25 11.7 0.0 0.4 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Myosin_head PF00063.21 EQB62280.1 - 4.6e-34 117.7 5.9 1.9e-32 112.3 5.9 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Pox_P21 PF05313.12 EQB62280.1 - 0.11 12.1 1.3 0.19 11.3 1.3 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF3450 PF11932.8 EQB62281.1 - 8.3 5.6 28.6 0.75 9.0 3.8 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) RT_RNaseH PF17917.1 EQB62283.1 - 8.8e-14 51.7 0.0 2.5e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EQB62283.1 - 2.7e-10 40.2 0.2 1.7e-09 37.6 0.1 2.4 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 EQB62283.1 - 0.00013 21.9 0.0 0.00035 20.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 EQB62283.1 - 0.011 15.9 0.5 0.033 14.4 0.1 2.1 2 0 0 2 2 2 0 H2C2 zinc finger rve_3 PF13683.6 EQB62283.1 - 0.045 13.5 0.1 0.15 11.9 0.1 1.9 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 EQB62283.1 - 0.06 13.5 0.4 0.27 11.4 0.4 2.1 1 1 0 1 1 1 0 Integrase core domain Integrase_H2C2 PF17921.1 EQB62284.1 - 5.6e-15 55.2 0.7 8.7e-15 54.6 0.7 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 EQB62284.1 - 1.3e-10 41.5 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 EQB62284.1 - 1.1e-05 25.5 0.2 1.8e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 H2C2 zinc finger BioT2 PF15368.6 EQB62285.1 - 0.0057 16.6 0.3 0.0059 16.6 0.3 1.1 1 0 0 1 1 1 1 Spermatogenesis family BioT2 RVT_1 PF00078.27 EQB62286.1 - 6.7e-10 38.9 0.9 5.3e-09 35.9 0.1 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_3 PF01381.22 EQB62291.1 - 8.4e-07 29.0 0.1 1.3e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EQB62291.1 - 0.006 16.6 0.5 0.009 16.0 0.5 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3420 PF11900.8 EQB62291.1 - 0.0062 16.7 0.6 0.0091 16.1 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3420) UPF0147 PF03685.13 EQB62291.1 - 0.0073 16.3 0.2 0.0084 16.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0147) Dict-STAT-coil PF09267.10 EQB62291.1 - 0.021 15.2 0.2 0.024 15.0 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil MqsA_antitoxin PF15731.5 EQB62291.1 - 0.036 14.2 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA LRR_8 PF13855.6 EQB62293.1 - 5.8e-19 67.6 17.8 2.5e-10 40.0 3.3 4.3 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EQB62293.1 - 4.9e-15 55.4 28.0 8.3e-08 32.4 2.1 5.0 1 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB62293.1 - 0.0001 22.3 19.4 0.47 11.2 0.1 6.4 5 2 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 EQB62293.1 - 0.057 13.5 20.0 1.1 9.5 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat RyR PF02026.16 EQB62294.1 - 0.065 13.4 8.1 0.082 13.1 2.3 3.2 1 1 1 3 3 3 0 RyR domain BIR PF00653.21 EQB62295.1 - 0.017 15.7 2.2 0.63 10.7 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain HNH_5 PF14279.6 EQB62295.1 - 0.044 13.7 0.2 0.044 13.7 0.2 2.1 2 0 0 2 2 2 0 HNH endonuclease Secretin_N_2 PF07655.13 EQB62297.1 - 0.29 11.7 17.3 0.44 11.1 17.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain UCH PF00443.29 EQB62298.1 - 1.5e-07 31.2 0.5 1.5e-07 31.2 0.5 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1419 PF07215.11 EQB62299.1 - 0.047 13.8 0.3 5.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) Peptidase_C16 PF01831.17 EQB62300.1 - 0.0029 17.4 0.5 0.0054 16.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase C16 family Ribosomal_L30 PF00327.20 EQB62301.1 - 1.9e-12 46.9 1.7 4.9e-12 45.5 1.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DAGK_acc PF00609.19 EQB62301.1 - 0.00067 20.0 0.7 0.0017 18.7 0.7 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain Dehalogenase PF13486.6 EQB62301.1 - 0.02 14.3 0.4 0.046 13.1 0.2 1.6 1 1 0 2 2 2 0 Reductive dehalogenase subunit ThiF PF00899.21 EQB62302.1 - 1.6e-78 263.5 0.0 1e-50 172.4 0.3 3.3 1 1 1 2 2 2 2 ThiF family E1_FCCH PF16190.5 EQB62302.1 - 8.6e-05 22.7 0.0 0.00026 21.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EQB62302.1 - 0.00029 21.0 0.1 0.00078 19.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 EQB62302.1 - 0.00096 19.2 1.2 1.8 8.6 0.1 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 EQB62302.1 - 0.0031 17.5 0.1 0.007 16.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EQB62302.1 - 0.034 14.6 1.2 16 6.0 0.8 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding HAS-barrel PF09378.10 EQB62302.1 - 0.13 12.5 0.1 0.53 10.5 0.1 2.1 2 0 0 2 2 2 0 HAS barrel domain UBA_e1_thiolCys PF10585.9 EQB62303.1 - 8.2e-15 55.4 1.9 6.8e-13 49.1 1.9 2.4 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 EQB62303.1 - 3.8e-05 23.2 0.0 0.00011 21.6 0.0 1.7 1 1 1 2 2 2 1 ThiF family E1_UFD PF09358.10 EQB62303.1 - 4e-05 24.2 0.4 9.2e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain TraF PF13728.6 EQB62305.1 - 0.082 12.7 0.3 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein NES_C_h PF18208.1 EQB62307.1 - 0.006 16.8 1.4 0.0077 16.5 1.4 1.2 1 0 0 1 1 1 1 Nicking enzyme C-terminal middle helical domain Homeobox_KN PF05920.11 EQB62308.1 - 2.7e-18 65.6 0.4 5.6e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EQB62308.1 - 4.2e-07 29.7 0.3 1.1e-06 28.4 0.3 1.7 1 0 0 1 1 1 1 Homeodomain Pkinase PF00069.25 EQB62309.1 - 4.4e-43 147.6 5.0 5.6e-43 147.2 5.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB62309.1 - 2.8e-19 69.4 0.3 3.3e-19 69.2 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EQB62309.1 - 0.00011 21.9 0.1 0.00029 20.5 0.1 1.7 1 1 0 1 1 1 1 Protein-kinase domain of FAM69 RIO1 PF01163.22 EQB62309.1 - 0.019 14.5 2.9 0.044 13.4 2.9 1.6 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 EQB62309.1 - 0.02 14.8 0.0 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EQB62309.1 - 0.041 13.5 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1196 PF06709.11 EQB62309.1 - 0.37 11.0 1.7 6.3 7.0 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1196) SNARE PF05739.19 EQB62311.1 - 0.0011 19.0 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Interfer-bind PF09294.10 EQB62311.1 - 2.9 8.3 7.6 2.7 8.4 5.1 2.0 1 1 1 2 2 2 0 Interferon-alpha/beta receptor, fibronectin type III Ribosomal_S13 PF00416.22 EQB62311.1 - 3.4 8.1 15.6 0.083 13.3 4.2 2.6 1 1 2 3 3 3 0 Ribosomal protein S13/S18 RT_RNaseH PF17917.1 EQB62314.1 - 3.5e-36 123.7 0.3 6.4e-36 122.8 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EQB62314.1 - 6.4e-27 93.5 0.0 1.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 EQB62314.1 - 2.7e-18 66.3 0.0 6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 EQB62314.1 - 7.9e-11 41.9 0.2 1.7e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Beta_lactamase3 PF17030.5 EQB62314.1 - 0.047 12.9 3.1 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Putative beta-lactamase-like family DUF5606 PF18347.1 EQB62314.1 - 0.18 12.0 0.1 15 5.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5606) RVT_1 PF00078.27 EQB62315.1 - 4.3e-34 118.0 2.5 4.3e-34 118.0 2.5 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med9 PF07544.13 EQB62316.1 - 0.15 12.2 5.4 3.4 7.8 0.1 3.1 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Retrotrans_gag PF03732.17 EQB62316.1 - 0.54 10.6 7.2 0.32 11.3 3.1 2.6 1 1 1 2 2 2 0 Retrotransposon gag protein Spore_II_R PF09551.10 EQB62316.1 - 0.72 10.3 8.2 0.096 13.1 3.4 2.0 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) CH PF00307.31 EQB62319.1 - 4.8e-07 29.9 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain OmdA PF13376.6 EQB62319.1 - 0.2 11.7 0.2 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated PPI_Ypi1 PF07491.11 EQB62322.1 - 2.7e-16 59.2 0.2 3.4e-16 58.8 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor RNA_pol_L_2 PF13656.6 EQB62322.1 - 0.036 13.8 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DIX PF00778.17 EQB62324.1 - 0.051 13.4 0.1 0.074 12.9 0.1 1.5 1 1 0 1 1 1 0 DIX domain Pkinase PF00069.25 EQB62327.1 - 2.9e-09 36.7 0.6 6.6e-05 22.4 0.4 2.1 2 0 0 2 2 2 2 Protein kinase domain Toprim_2 PF13155.6 EQB62328.1 - 0.079 13.4 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Toprim-like PDEase_I PF00233.19 EQB62328.1 - 0.11 12.2 5.8 0.2 11.4 5.1 1.8 1 1 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Lipoprotein_3 PF00938.17 EQB62328.1 - 0.23 11.7 3.8 0.26 11.5 0.6 2.6 2 1 0 2 2 2 0 Lipoprotein AAA_12 PF13087.6 EQB62331.1 - 7.8e-44 149.7 1.2 7.8e-44 149.7 1.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EQB62331.1 - 8.1e-34 117.6 0.4 1.3e-16 61.1 0.1 2.6 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EQB62331.1 - 6.9e-12 45.9 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EQB62331.1 - 1.8e-11 44.2 0.0 5.5e-07 29.6 0.0 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EQB62331.1 - 1.1e-07 32.0 1.8 1.1e-07 32.0 1.8 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EQB62331.1 - 2.7e-06 27.3 0.0 2.7e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EQB62331.1 - 1.1e-05 25.1 10.3 0.002 17.7 0.0 3.5 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EQB62331.1 - 2.5e-05 24.2 0.0 0.00015 21.6 0.0 2.3 2 1 0 2 2 2 1 Helicase AAA_22 PF13401.6 EQB62331.1 - 0.00045 20.5 0.0 0.0036 17.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EQB62331.1 - 0.0038 16.5 0.1 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 EQB62331.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 EQB62331.1 - 0.0091 16.4 0.3 0.052 14.0 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EQB62331.1 - 0.012 15.6 0.0 0.063 13.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EQB62331.1 - 0.016 14.7 0.0 0.052 13.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EQB62331.1 - 0.033 14.2 0.0 0.13 12.3 0.0 1.9 1 1 1 2 2 2 0 Flavivirus DEAD domain RNA_helicase PF00910.22 EQB62331.1 - 0.038 14.4 0.0 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase ANAPC9 PF12856.7 EQB62331.1 - 2.8 8.1 8.1 2.6 8.2 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 9 zf-RING_2 PF13639.6 EQB62332.1 - 0.00062 20.1 8.6 0.00062 20.1 8.6 2.2 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 EQB62332.1 - 0.0034 17.5 8.3 0.013 15.6 8.3 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EQB62332.1 - 0.012 15.9 7.4 0.032 14.5 7.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EQB62332.1 - 0.019 15.0 4.7 0.043 13.9 4.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EQB62332.1 - 0.33 10.9 8.7 1.2 9.0 8.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EQB62332.1 - 0.7 10.3 6.3 1.8 8.9 6.3 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 EQB62332.1 - 0.72 9.8 8.9 4.2 7.3 9.0 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EQB62332.1 - 1.5 8.5 6.2 5 6.8 6.2 1.9 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EQB62332.1 - 1.9 8.4 8.4 6.9 6.6 8.4 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CLP1_N PF16573.5 EQB62333.1 - 1.9e-21 76.0 0.1 4e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EQB62333.1 - 1.4e-08 35.2 0.0 2.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 RdRP PF05183.12 EQB62335.1 - 4e-80 270.1 0.7 6.7e-79 266.1 0.7 2.2 1 1 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.12 EQB62336.1 - 2.5e-34 118.9 0.0 2.7e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase Presenilin PF01080.17 EQB62340.1 - 0.48 9.1 1.2 0.56 8.9 1.2 1.1 1 0 0 1 1 1 0 Presenilin UCMA PF17085.5 EQB62341.1 - 0.16 12.0 2.7 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Unique cartilage matrix associated protein SNARE PF05739.19 EQB62342.1 - 0.00044 20.2 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 SNARE domain DUF2207 PF09972.9 EQB62342.1 - 0.074 11.8 1.1 0.087 11.6 1.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BLYB PF05289.11 EQB62342.1 - 0.15 12.3 4.3 0.2 11.9 4.3 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein PRKG1_interact PF15898.5 EQB62342.1 - 0.15 12.9 3.9 0.21 12.5 3.9 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Ribosomal_S13 PF00416.22 EQB62342.1 - 0.32 11.4 4.9 0.36 11.2 2.9 1.9 1 1 1 2 2 2 0 Ribosomal protein S13/S18 Pkinase PF00069.25 EQB62344.1 - 4.1e-32 111.6 5.4 4.8e-32 111.4 5.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EQB62344.1 - 1.2e-14 54.3 1.0 1.4e-14 54.0 1.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EQB62344.1 - 4.7e-05 23.1 0.1 9.5e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 Protein-kinase domain of FAM69 Pkinase_fungal PF17667.1 EQB62344.1 - 0.00076 18.4 0.5 0.0012 17.7 0.4 1.3 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EQB62344.1 - 0.0055 16.3 3.1 0.011 15.4 3.1 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EQB62344.1 - 0.0059 16.6 0.0 0.39 10.6 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EQB62344.1 - 0.031 13.9 0.2 0.066 12.8 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 XPG_I PF00867.18 EQB62347.1 - 1.6e-31 108.5 1.0 4.3e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EQB62347.1 - 2.7e-28 98.4 0.2 1.4e-27 96.1 0.1 2.2 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EQB62347.1 - 0.0001 22.8 2.0 0.00014 22.4 0.1 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 EQB62347.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 XPG domain containing PI3_PI4_kinase PF00454.27 EQB62349.1 - 1.1e-21 77.8 0.3 3.2e-21 76.3 0.3 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ArenaCapSnatch PF17296.2 EQB62351.1 - 0.014 14.8 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain Myb_DNA-bind_7 PF15963.5 EQB62352.1 - 2.7e-21 75.3 6.4 2.7e-21 75.3 6.4 1.6 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EQB62352.1 - 6.7e-07 29.4 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EQB62352.1 - 0.00013 22.2 0.4 0.0003 21.0 0.4 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain AAA_22 PF13401.6 EQB62353.1 - 2.9e-11 43.8 0.1 5.7e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EQB62353.1 - 5.3e-11 43.1 0.1 8.9e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EQB62353.1 - 1.2e-08 35.5 0.0 0.00032 21.1 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain Viral_helicase1 PF01443.18 EQB62353.1 - 4.8e-06 26.5 0.0 9.4e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 EQB62353.1 - 6.2e-05 22.9 0.8 0.00012 22.0 0.8 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein Cdc6_C PF09079.11 EQB62353.1 - 0.00017 21.5 0.0 0.00051 20.0 0.0 1.9 2 0 0 2 2 1 1 CDC6, C terminal winged helix domain AAA_14 PF13173.6 EQB62353.1 - 0.00027 21.0 0.2 0.00076 19.5 0.2 1.9 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EQB62353.1 - 0.0009 18.6 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Kinesin PF00225.23 EQB62353.1 - 0.0022 17.0 0.1 0.0029 16.6 0.1 1.3 1 1 0 1 1 1 1 Kinesin motor domain AAA_lid_10 PF17872.1 EQB62353.1 - 0.0026 17.8 0.1 0.0067 16.5 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain Zeta_toxin PF06414.12 EQB62353.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EQB62353.1 - 0.0077 16.6 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EQB62353.1 - 0.0089 16.0 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EQB62353.1 - 0.012 14.7 0.2 0.027 13.5 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EQB62353.1 - 0.015 15.2 0.2 0.22 11.5 0.2 2.1 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EQB62353.1 - 0.017 15.0 7.0 0.42 10.5 0.1 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EQB62353.1 - 0.032 14.0 0.0 0.074 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EQB62353.1 - 0.036 14.0 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 EQB62353.1 - 0.096 12.4 0.7 7.2 6.3 0.7 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EQB62353.1 - 0.12 12.9 0.1 0.24 11.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EQB62353.1 - 0.13 12.0 0.1 0.44 10.2 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain BH3 PF15285.6 EQB62353.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting RNA_helicase PF00910.22 EQB62353.1 - 0.24 11.8 1.3 1.1 9.6 0.7 2.4 2 1 0 2 2 2 0 RNA helicase DEAD PF00270.29 EQB62353.1 - 0.3 10.8 1.4 1.2 8.9 0.2 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase Creatinase_N_2 PF16189.5 EQB62354.1 - 8.6e-15 55.2 0.0 8.2e-14 52.0 0.0 2.2 1 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Far-17a_AIG1 PF04750.14 EQB62355.1 - 5.3e-24 84.7 19.3 6.7e-24 84.3 19.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein PQQ_3 PF13570.6 EQB62356.1 - 0.017 15.6 0.0 32 5.2 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 EQB62356.1 - 0.2 12.6 0.8 4.1 8.4 0.0 3.2 2 1 0 2 2 2 0 WD domain, G-beta repeat 14-3-3 PF00244.20 EQB62358.1 - 2.5e-81 272.4 6.2 2.9e-81 272.2 6.2 1.0 1 0 0 1 1 1 1 14-3-3 protein RNase_P_p30 PF01876.16 EQB62358.1 - 0.049 13.1 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit p30 DASH_Dad3 PF08656.10 EQB62358.1 - 0.082 13.0 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad3 EF-hand_6 PF13405.6 EQB62359.1 - 0.017 15.0 0.4 0.095 12.7 0.4 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EQB62359.1 - 0.03 13.9 0.4 0.16 11.6 0.4 2.3 1 0 0 1 1 1 0 EF hand MS_channel PF00924.18 EQB62360.1 - 3.2e-11 43.2 5.4 3.2e-11 43.2 5.4 1.4 1 1 0 1 1 1 1 Mechanosensitive ion channel LRR_8 PF13855.6 EQB62363.1 - 3.4e-25 87.6 40.2 1.7e-10 40.5 9.2 5.9 3 2 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EQB62363.1 - 1.3e-16 60.4 55.9 2.5e-07 30.9 2.0 7.7 1 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB62363.1 - 0.0045 17.3 42.2 2.4 9.0 0.1 9.2 8 3 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 EQB62363.1 - 0.11 12.5 46.1 0.34 11.1 0.3 9.6 10 1 1 11 11 11 0 Leucine Rich repeat Retrotrans_gag PF03732.17 EQB62364.1 - 0.0028 17.9 0.0 0.005 17.1 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 EQB62364.1 - 0.0046 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 EQB62364.1 - 0.023 14.8 0.6 0.041 14.0 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EQB62364.1 - 0.19 11.5 1.5 0.4 10.4 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EQB62364.1 - 0.55 10.1 3.3 1 9.2 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 EQB62366.1 - 1.1e-33 116.6 0.2 1.8e-33 116.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EQB62367.1 - 1.2e-17 64.2 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EQB62367.1 - 4.3e-05 23.2 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Imm64 PF15600.6 EQB62367.1 - 0.032 13.9 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 64 gag-asp_proteas PF13975.6 EQB62369.1 - 0.0079 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EQB62369.1 - 0.019 15.6 0.0 0.038 14.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Bac_DnaA PF00308.18 EQB62370.1 - 0.019 14.8 2.5 0.58 10.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Methyltransf_12 PF08242.12 EQB62370.1 - 0.051 14.3 0.5 0.13 13.0 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain LRR_8 PF13855.6 EQB62371.1 - 4.2e-32 109.7 58.8 1.1e-10 41.1 5.7 5.5 2 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EQB62371.1 - 1.3e-27 95.4 78.8 6.6e-08 32.7 8.5 7.1 4 3 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EQB62371.1 - 6.4e-06 26.0 67.9 4.3 8.3 0.3 11.7 12 0 0 12 12 12 7 Leucine Rich Repeat LRR_9 PF14580.6 EQB62371.1 - 1.3e-05 24.8 29.6 0.0022 17.5 10.1 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EQB62371.1 - 0.003 17.5 53.7 1.2 9.3 0.0 10.6 11 0 0 11 11 11 5 Leucine Rich repeat LRR_5 PF13306.6 EQB62371.1 - 6.7 6.7 40.1 0.036 14.0 16.1 3.0 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF1002 PF06207.11 EQB62371.1 - 9.2 5.7 12.5 1.7 8.1 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1002) SH3_13 PF18335.1 EQB62372.1 - 0.11 12.3 0.2 0.16 11.9 0.2 1.4 1 1 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain RT_RNaseH_2 PF17919.1 EQB62373.1 - 2e-14 53.4 0.0 3.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EQB62373.1 - 1.1e-08 35.4 0.0 3.2e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_thumb PF06817.14 EQB62373.1 - 0.00027 20.7 0.6 0.00047 19.9 0.6 1.4 1 0 0 1 1 1 1 Reverse transcriptase thumb domain EPOP PF15223.6 EQB62377.1 - 2.6 7.3 9.1 3.8 6.8 9.1 1.2 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein BCL_N PF04714.13 EQB62378.1 - 0.031 14.3 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 BCL7, N-terminal conserver region DdrB PF12747.7 EQB62378.1 - 0.1 12.4 0.8 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 DdrB-like protein Ntox16 PF15523.6 EQB62378.1 - 3.8 7.8 8.9 0.3 11.3 1.7 2.7 3 0 0 3 3 3 0 Novel toxin 16 Cas9_PI2 PF18070.1 EQB62380.1 - 1.3 9.9 8.3 9.7 7.0 0.4 3.1 3 0 0 3 3 3 0 CRISPR-Cas9 PI domain DUF572 PF04502.13 EQB62381.1 - 8.3e-26 91.4 15.4 8.8e-26 91.3 15.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Zn_ribbon_SprT PF17283.2 EQB62381.1 - 0.0052 16.7 2.8 0.01 15.7 2.8 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF866 PF05907.13 EQB62381.1 - 0.11 12.4 11.1 0.088 12.7 8.8 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) zf-H2C2_2 PF13465.6 EQB62382.1 - 2.2e-11 43.7 14.4 4.7e-09 36.3 4.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EQB62382.1 - 5.5e-10 39.1 8.7 0.00011 22.4 0.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EQB62382.1 - 6.1e-06 26.6 8.2 0.01 16.6 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EQB62382.1 - 0.001 19.6 1.8 1.4 9.6 0.2 2.2 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-TRAF PF02176.18 EQB62382.1 - 0.0091 16.7 2.1 0.014 16.1 1.9 1.5 1 1 0 1 1 1 1 TRAF-type zinc finger Ogr_Delta PF04606.12 EQB62382.1 - 0.015 15.2 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2HE PF16278.5 EQB62382.1 - 0.017 15.6 0.1 0.029 14.8 0.1 1.4 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger DUF448 PF04296.13 EQB62382.1 - 0.02 14.7 0.5 1.5 8.7 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF448) zf-C2H2_8 PF15909.5 EQB62382.1 - 0.036 14.4 2.7 0.37 11.1 2.0 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EQB62382.1 - 0.094 12.9 2.6 1.8 8.7 0.1 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 EQB62382.1 - 0.65 9.8 13.4 2.6 7.9 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain tRNA-synt_1d PF00750.19 EQB62383.1 - 2.4e-76 257.0 8.0 3.4e-76 256.4 8.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EQB62383.1 - 9.8e-17 61.2 0.0 2.8e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain TMF_TATA_bd PF12325.8 EQB62384.1 - 0.049 13.9 10.3 0.15 12.3 10.3 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF3492 PF11997.8 EQB62384.1 - 3.3 7.4 10.2 0.46 10.2 6.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Calsequestrin PF01216.17 EQB62385.1 - 0.0014 17.8 1.1 0.0016 17.5 1.1 1.1 1 0 0 1 1 1 1 Calsequestrin QSOX_Trx1 PF18108.1 EQB62385.1 - 0.11 12.7 1.2 3.4 7.9 0.2 2.1 2 0 0 2 2 2 0 QSOX Trx-like domain Ribosomal_L18A PF01775.17 EQB62386.1 - 3.9e-22 78.6 0.5 5.4e-22 78.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Cnd1 PF12717.7 EQB62387.1 - 0.00055 20.0 6.9 0.00055 20.0 6.9 5.2 4 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EQB62387.1 - 0.02 15.1 0.0 5 7.7 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 EQB62387.1 - 0.092 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats DNA_primase_S PF01896.19 EQB62388.1 - 1.4e-18 67.5 0.6 2.1e-18 67.0 0.6 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF313 PF03754.13 EQB62390.1 - 0.41 10.9 3.9 0.17 12.1 0.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF313) Serpin PF00079.20 EQB62391.1 - 3.4e-50 171.4 17.6 3.8e-50 171.3 17.6 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Aa_trans PF01490.18 EQB62394.1 - 9.9e-09 34.4 3.4 1.1e-08 34.2 3.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Com_YlbF PF06133.11 EQB62398.1 - 0.0032 18.0 4.8 0.015 15.9 1.1 2.2 2 0 0 2 2 2 1 Control of competence regulator ComK, YlbF/YmcA DUF2028 PF09667.10 EQB62398.1 - 0.0085 16.1 2.4 0.014 15.3 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2028) DUF600 PF04634.12 EQB62398.1 - 0.19 11.8 7.0 0.27 11.3 7.0 1.3 1 1 0 1 1 1 0 Protein of unknown function, DUF600 DUF1462 PF07315.11 EQB62399.1 - 0.3 11.4 2.5 0.34 11.2 0.9 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1462) Nucleopor_Nup85 PF07575.13 EQB62400.1 - 0.00086 18.0 0.3 0.00098 17.8 0.3 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin KASH_CCD PF14662.6 EQB62400.1 - 0.0067 16.3 5.0 0.25 11.2 1.0 2.0 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Cbl_N2 PF02761.14 EQB62400.1 - 0.016 15.9 0.4 0.023 15.4 0.3 1.4 1 1 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain PTPA PF03095.15 EQB62400.1 - 0.022 14.2 0.1 0.024 14.1 0.1 1.0 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein HD_3 PF13023.6 EQB62400.1 - 0.035 14.0 1.0 0.04 13.8 1.0 1.1 1 0 0 1 1 1 0 HD domain TENA_THI-4 PF03070.16 EQB62400.1 - 0.058 13.2 0.2 0.063 13.1 0.2 1.1 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Flavodoxin_1 PF00258.25 EQB62400.1 - 0.072 13.3 0.3 0.086 13.1 0.3 1.1 1 0 0 1 1 1 0 Flavodoxin Coatomer_g_Cpla PF16381.5 EQB62400.1 - 0.08 13.1 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform PDH PF02153.17 EQB62400.1 - 0.095 11.7 1.9 0.18 10.8 1.3 1.5 1 1 1 2 2 2 0 Prephenate dehydrogenase DUF677 PF05055.12 EQB62400.1 - 0.79 8.5 7.1 1 8.2 7.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Asp-B-Hydro_N PF05279.11 EQB62403.1 - 1.8 8.5 21.4 2.2 8.3 21.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APC_N_CC PF16689.5 EQB62403.1 - 2.5 8.2 10.1 13 5.9 0.3 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain SPACA9 PF15120.6 EQB62404.1 - 0.0043 16.8 2.3 0.92 9.3 0.2 2.1 1 1 1 2 2 2 2 Sperm acrosome-associated protein 9 Sec20 PF03908.13 EQB62404.1 - 0.0045 16.9 2.3 0.0068 16.3 0.1 2.1 2 0 0 2 2 2 1 Sec20 DctP PF03480.13 EQB62404.1 - 0.096 12.0 0.3 6.4 6.0 0.0 2.0 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 HATPase_c_5 PF14501.6 EQB62404.1 - 1.7 8.6 7.0 6 6.8 0.1 2.4 2 1 0 2 2 2 0 GHKL domain Pox_D5 PF03288.16 EQB62405.1 - 0.018 15.6 0.6 0.08 13.4 0.2 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like SIP1 PF04938.12 EQB62405.1 - 0.027 14.2 0.1 0.037 13.8 0.1 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Pox_Ag35 PF03286.14 EQB62406.1 - 0.057 13.2 4.8 0.067 13.0 4.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hydrolase PF00702.26 EQB62409.1 - 4.4e-07 30.4 0.0 0.0045 17.3 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EQB62409.1 - 4.3e-05 23.4 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4177 PF13783.6 EQB62409.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) E1-E2_ATPase PF00122.20 EQB62410.1 - 4.4e-20 72.0 0.0 3e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 E1-E2 ATPase P5-ATPase PF12409.8 EQB62411.1 - 1.5e-09 38.0 1.3 5.7e-09 36.1 0.2 1.9 1 1 1 2 2 2 1 P5-type ATPase cation transporter DHHW PF14286.6 EQB62416.1 - 0.054 12.8 0.1 0.062 12.6 0.1 1.0 1 0 0 1 1 1 0 DHHW protein LRR_8 PF13855.6 EQB62418.1 - 2.1e-20 72.2 21.9 7.4e-08 32.0 2.5 3.2 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EQB62418.1 - 2.5e-14 53.1 31.4 2.6e-05 24.5 4.4 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EQB62418.1 - 3.8e-06 26.5 26.0 0.044 13.9 0.3 6.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_9 PF14580.6 EQB62418.1 - 0.00019 20.9 11.0 0.023 14.2 7.6 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 EQB62418.1 - 0.00087 19.3 11.0 0.0026 17.7 2.4 2.0 1 1 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 EQB62418.1 - 0.0023 18.5 4.6 0.023 15.4 0.6 3.7 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_1 PF00560.33 EQB62418.1 - 0.011 16.1 31.6 3.1 8.7 0.9 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat FAD_SOX PF18371.1 EQB62419.1 - 1.3 9.4 5.4 1.3 9.4 0.2 3.3 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase FAD_SOX PF18371.1 EQB62420.1 - 0.055 13.8 0.5 0.12 12.7 0.5 1.6 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Nosema_apis_BRL_01-NapisBRLv01/GCA_000447185.1_NapisBRLv01_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Nosema_apis_BRL_01-NapisBRLv01/GCA_000447185.1_NapisBRLv01_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Nosema_apis_BRL_01-NapisBRLv01/GCA_000447185.1_NapisBRLv01_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Nosema_apis_BRL_01-NapisBRLv01/GCA_000447185.1_NapisBRLv01_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:55:36 2019 # [ok]