# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Reg_prop PF07494.11 OIR55561.1 - 0.02 15.0 0.1 5.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Two component regulator propeller Spore_coat_CotO PF14153.6 OIR55563.1 - 1.6 8.7 11.0 1.9 8.4 11.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF3253 PF11625.8 OIR55568.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) UPF0228 PF05727.11 OIR55569.1 - 0.12 12.2 1.0 9.7 6.0 0.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0228) zf-C3HC4_3 PF13920.6 OIR55571.1 - 4.3e-06 26.5 7.6 6.9e-06 25.8 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55571.1 - 0.00013 22.0 6.0 0.0002 21.4 6.0 1.2 1 0 0 1 1 1 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR55571.1 - 0.00057 20.1 6.6 0.00071 19.8 6.6 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR55571.1 - 0.0024 17.6 8.6 0.051 13.4 7.9 2.4 1 1 1 2 2 2 2 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR55571.1 - 0.0085 16.0 6.3 0.0092 15.9 5.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Stc1 PF12898.7 OIR55571.1 - 0.02 15.4 5.3 0.31 11.6 2.0 2.1 2 0 0 2 2 2 0 Stc1 domain zf-Di19 PF05605.12 OIR55571.1 - 0.023 15.0 8.6 0.054 13.8 2.6 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Cys_rich_KTR PF14205.6 OIR55571.1 - 0.034 13.9 0.1 0.034 13.9 0.1 2.4 2 1 0 2 2 2 0 Cysteine-rich KTR DZR PF12773.7 OIR55571.1 - 0.038 14.0 5.4 2.1 8.4 6.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.6 OIR55571.1 - 0.066 13.2 3.2 0.24 11.5 3.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger HypA PF01155.19 OIR55571.1 - 0.096 12.7 7.7 0.41 10.7 2.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-XS PF03470.14 OIR55571.1 - 0.19 12.0 1.7 0.33 11.2 1.7 1.4 1 0 0 1 1 1 0 XS zinc finger domain DUF4451 PF14616.6 OIR55571.1 - 0.31 11.3 8.0 0.1 12.8 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-C3HC4_4 PF15227.6 OIR55571.1 - 0.45 10.7 6.6 4.4 7.6 7.1 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-4CXXC_R1 PF10497.9 OIR55571.1 - 0.46 10.7 7.1 0.93 9.8 6.2 1.9 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF2197 PF09963.9 OIR55571.1 - 0.65 10.3 9.7 0.99 9.7 6.3 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-BED PF02892.15 OIR55571.1 - 0.73 9.9 6.6 6.8 6.8 0.0 2.8 2 1 0 2 2 2 0 BED zinc finger zf-CHY PF05495.12 OIR55571.1 - 0.87 10.1 8.5 5.5 7.6 8.5 2.1 1 1 0 1 1 1 0 CHY zinc finger OrfB_Zn_ribbon PF07282.11 OIR55571.1 - 3 7.8 6.7 1.1 9.3 2.2 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain RT_RNaseH PF17917.1 OIR55572.1 - 8.6e-38 128.8 0.0 9.4e-38 128.7 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OIR55572.1 - 3.2e-27 94.5 0.0 4.3e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OIR55573.1 - 2.9e-14 53.1 0.0 4.6e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 OIR55575.1 - 4.5e-21 75.4 0.1 5.1e-21 75.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55575.1 - 5.8e-13 48.7 0.0 6.8e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR55575.1 - 1.2e-06 28.0 0.1 1.3e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR55575.1 - 2.2e-05 23.6 0.0 2.2e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR55575.1 - 0.0022 17.9 0.0 0.0024 17.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OIR55575.1 - 0.0089 15.6 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OIR55575.1 - 0.085 12.2 0.0 0.092 12.0 0.0 1.0 1 0 0 1 1 1 0 Kinase-like Capsule_synth PF05159.14 OIR55575.1 - 0.098 12.1 0.2 0.11 11.9 0.2 1.0 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein FTA2 PF13095.6 OIR55575.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OIR55575.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF3060 PF11259.8 OIR55577.1 - 0.079 12.7 0.0 11 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) DUF2110 PF09883.9 OIR55577.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) MlaD PF02470.20 OIR55577.1 - 0.16 12.3 0.0 7.7 6.9 0.0 2.1 2 0 0 2 2 2 0 MlaD protein Pkinase PF00069.25 OIR55579.1 - 5.8e-10 39.0 0.2 7.1e-10 38.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55579.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2714 PF10896.8 OIR55580.1 - 0.063 13.3 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2714) PPTA PF01239.22 OIR55581.1 - 0.00025 20.6 2.5 0.17 11.6 0.2 2.4 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat PHM7_ext PF12621.8 OIR55581.1 - 0.025 14.8 0.0 3.9 7.7 0.0 2.0 2 0 0 2 2 2 0 Extracellular tail, of 10TM putative phosphate transporter ANAPC15 PF15243.6 OIR55581.1 - 0.054 13.9 0.3 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 UQ_con PF00179.26 OIR55583.1 - 9e-36 122.6 0.0 1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR55583.1 - 2.3e-05 24.1 0.0 2.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OIR55583.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 OIR55583.1 - 0.038 13.9 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 OIR55583.1 - 0.04 13.6 0.1 0.066 12.8 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Reovirus_cap PF00979.17 OIR55584.1 - 0.12 11.5 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Reovirus outer capsid protein, Sigma 3 zf-C3HC4_3 PF13920.6 OIR55587.1 - 2.2e-07 30.6 6.5 2.2e-07 30.6 6.5 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55587.1 - 3.8e-05 23.7 4.0 6.1e-05 23.1 4.0 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR55587.1 - 0.00068 19.9 7.6 0.00068 19.9 7.6 1.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_4 PF14570.6 OIR55587.1 - 0.0026 17.5 8.8 0.099 12.5 8.9 2.4 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR55587.1 - 0.013 15.7 6.2 0.022 15.0 6.0 1.4 1 1 1 2 2 2 0 FYVE-type zinc finger zf-Di19 PF05605.12 OIR55587.1 - 0.018 15.4 7.1 0.062 13.6 2.2 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR55587.1 - 0.035 14.1 6.7 0.035 14.1 6.7 1.7 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 OIR55587.1 - 0.047 13.7 5.6 1.3 9.1 5.6 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4 PF00097.25 OIR55587.1 - 0.09 12.7 4.4 0.26 11.2 4.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Stc1 PF12898.7 OIR55587.1 - 0.093 13.3 5.2 0.87 10.2 1.3 2.2 2 0 0 2 2 2 0 Stc1 domain Prok-RING_1 PF14446.6 OIR55587.1 - 0.19 11.7 6.5 0.42 10.6 0.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 OIR55587.1 - 0.45 10.7 7.4 0.16 12.1 2.0 2.6 1 1 3 4 4 4 0 zinc finger of C3HC4-type, RING TF_Zn_Ribbon PF08271.12 OIR55587.1 - 0.69 9.5 7.5 0.84 9.2 0.1 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding DUF4451 PF14616.6 OIR55587.1 - 0.76 10.0 7.9 5 7.4 5.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-BED PF02892.15 OIR55587.1 - 0.98 9.5 10.9 8.6 6.5 0.8 3.6 2 2 0 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.11 OIR55587.1 - 2.3 8.2 7.2 0.76 9.7 2.2 2.1 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RVT_1 PF00078.27 OIR55588.1 - 0.00072 19.1 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NikR_C PF08753.11 OIR55591.1 - 0.066 13.4 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 NikR C terminal nickel binding domain NikR_C PF08753.11 OIR55592.1 - 0.03 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 NikR C terminal nickel binding domain DUF4506 PF14958.6 OIR55594.1 - 0.0068 15.9 2.8 0.91 9.0 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4506) Siah-Interact_N PF09032.11 OIR55594.1 - 0.0091 16.3 0.1 3.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Siah interacting protein, N terminal FHA_2 PF17913.1 OIR55594.1 - 0.072 13.3 0.6 2.5 8.4 0.0 2.2 1 1 1 2 2 2 0 FHA domain zf-CCHC PF00098.23 OIR55597.1 - 9.4e-07 28.6 2.5 1.8e-06 27.8 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OIR55597.1 - 0.0046 16.7 0.8 0.0046 16.7 0.8 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 OIR55597.1 - 0.011 15.7 0.7 0.022 14.7 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Med8 PF10232.9 OIR55603.1 - 0.076 12.6 1.2 0.095 12.3 1.2 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Med8 PF10232.9 OIR55604.1 - 0.13 11.8 1.3 0.16 11.5 1.3 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 zf-C3HC4_3 PF13920.6 OIR55607.1 - 0.0012 18.7 0.9 0.0015 18.4 0.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR55607.1 - 0.0018 18.5 2.5 0.0027 18.0 2.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 OIR55607.1 - 0.0019 17.9 0.9 0.0029 17.3 0.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR55607.1 - 0.008 16.1 2.8 0.012 15.5 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OIR55607.1 - 0.041 13.7 3.8 0.1 12.4 3.8 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OIR55607.1 - 0.083 13.1 4.0 0.15 12.3 4.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Headcase PF16002.5 OIR55609.1 - 0.097 12.1 0.7 0.14 11.6 0.7 1.2 1 0 0 1 1 1 0 Headcase protein HypA PF01155.19 OIR55609.1 - 0.28 11.2 2.7 0.45 10.6 1.8 1.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA R-HINP1I PF11463.8 OIR55616.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 R.HinP1I restriction endonuclease Sep15_SelM PF08806.11 OIR55616.1 - 0.11 12.7 0.1 2.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Sep15/SelM redox domain RVT_1 PF00078.27 OIR55619.1 - 0.0025 17.4 0.0 0.0031 17.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-UDP PF14569.6 OIR55620.1 - 0.0014 18.7 2.1 0.0023 18.0 2.1 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OIR55620.1 - 0.0021 17.9 3.2 0.0044 16.9 3.2 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OIR55620.1 - 0.01 15.7 1.6 0.017 15.0 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR55620.1 - 0.19 11.7 3.4 0.3 11.1 3.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sep15_SelM PF08806.11 OIR55621.1 - 5.2e-05 23.3 0.7 0.25 11.5 0.1 2.2 2 0 0 2 2 2 2 Sep15/SelM redox domain TbpB_C PF17483.2 OIR55621.1 - 0.013 15.9 0.0 0.02 15.2 0.0 1.3 1 1 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Eco57I PF07669.11 OIR55621.1 - 0.05 14.1 0.1 8.2 7.0 0.0 2.0 1 1 1 2 2 2 0 Eco57I restriction-modification methylase DUF2577 PF10844.8 OIR55621.1 - 0.16 12.2 0.1 1.4 9.2 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2577) zf-C3HC4_3 PF13920.6 OIR55623.1 - 1.1e-06 28.4 8.7 1.5e-06 27.9 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR55623.1 - 5.5e-05 22.9 6.9 0.0003 20.6 7.1 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OIR55623.1 - 0.00012 22.3 8.9 0.00017 21.8 8.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 OIR55623.1 - 0.00054 19.7 8.5 0.0019 18.0 8.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR55623.1 - 0.0015 18.7 2.9 0.0019 18.4 2.9 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger FAM35_C PF15793.5 OIR55623.1 - 0.0027 17.2 0.4 0.003 17.0 0.4 1.1 1 0 0 1 1 1 1 Protein family FAM35, C-terminal zf-RING_UBOX PF13445.6 OIR55623.1 - 0.053 13.6 1.6 0.053 13.6 1.6 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OIR55623.1 - 0.08 12.8 5.8 0.17 11.8 5.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.15 OIR55623.1 - 0.1 12.6 7.9 1.6 8.8 0.4 3.0 1 1 1 2 2 2 0 BED zinc finger DZR PF12773.7 OIR55623.1 - 0.11 12.5 6.2 0.89 9.6 2.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon Cytochrom_CIII PF02085.16 OIR55623.1 - 0.18 12.2 4.3 0.26 11.7 4.3 1.3 1 0 0 1 1 1 0 Class III cytochrome C family zf-4CXXC_R1 PF10497.9 OIR55623.1 - 0.23 11.7 5.9 0.43 10.8 6.0 1.4 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-Di19 PF05605.12 OIR55623.1 - 0.25 11.7 8.1 1 9.7 0.3 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR55623.1 - 0.28 11.2 7.6 0.68 9.9 7.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OIR55623.1 - 0.28 11.4 6.2 0.38 10.9 2.7 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF2024 PF09630.10 OIR55623.1 - 0.38 10.7 3.2 4.7 7.2 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) Cytochrome_C7 PF14522.6 OIR55623.1 - 0.65 10.0 5.2 5.5 7.1 5.2 2.1 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-CHY PF05495.12 OIR55623.1 - 0.89 10.1 7.5 3.2 8.3 7.5 1.9 1 1 0 1 1 1 0 CHY zinc finger DUF4451 PF14616.6 OIR55623.1 - 2.6 8.3 6.8 36 4.6 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Prok-RING_1 PF14446.6 OIR55623.1 - 4 7.4 9.6 22 5.1 4.3 2.5 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C4_ClpX PF06689.13 OIR55623.1 - 4.3 7.3 9.3 0.6 10.0 2.5 2.4 2 1 0 2 2 2 0 ClpX C4-type zinc finger zf-C3HC4_3 PF13920.6 OIR55624.1 - 0.00071 19.4 7.3 0.0014 18.5 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55624.1 - 0.0015 18.6 6.5 0.0024 17.9 6.5 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger DUF2197 PF09963.9 OIR55624.1 - 0.039 14.2 6.1 0.16 12.2 6.1 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) RuBisCO_large_N PF02788.16 OIR55626.1 - 0.077 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain FHA_2 PF17913.1 OIR55627.1 - 3.3e-05 24.1 0.1 0.065 13.5 0.0 2.6 1 1 2 3 3 3 2 FHA domain Flt3_lig PF02947.14 OIR55627.1 - 0.0058 16.8 0.2 1.2 9.3 0.1 2.1 1 1 1 2 2 2 2 flt3 ligand QSOX_Trx1 PF18108.1 OIR55627.1 - 0.014 15.5 0.5 8.7 6.6 0.0 2.7 1 1 2 3 3 3 0 QSOX Trx-like domain LRR_8 PF13855.6 OIR55628.1 - 0.042 13.6 0.0 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat FHA_2 PF17913.1 OIR55629.1 - 0.00081 19.6 0.4 1.6 9.0 0.0 2.6 1 1 2 3 3 3 2 FHA domain Flt3_lig PF02947.14 OIR55629.1 - 0.0051 17.0 0.3 2.6 8.3 0.1 2.1 1 1 1 2 2 2 2 flt3 ligand HIF-1a_CTAD PF08778.10 OIR55629.1 - 0.2 11.3 0.4 6.6 6.4 0.1 2.3 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain OAF PF14941.6 OIR55630.1 - 0.026 14.0 0.4 0.028 13.8 0.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator, Out at first DUF3808 PF10300.9 OIR55630.1 - 0.029 13.1 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) DUF3545 PF12065.8 OIR55633.1 - 0.0023 17.9 0.0 0.0083 16.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3545) UMPH-1 PF05822.12 OIR55635.1 - 0.061 12.8 0.7 0.067 12.7 0.7 1.4 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Pkinase PF00069.25 OIR55636.1 - 3.1e-16 59.5 0.0 3.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55636.1 - 2.2e-08 33.7 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR55636.1 - 0.00053 19.4 0.0 0.0007 19.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.6 OIR55637.1 - 0.0085 15.9 3.9 0.017 15.0 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55637.1 - 2.1 8.5 8.3 1.7 8.8 5.0 2.1 2 1 0 2 2 2 0 Zinc-binding RING-finger RVT_1 PF00078.27 OIR55640.1 - 8e-07 28.8 0.0 9.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Destabilase PF05497.12 OIR55640.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Destabilase DUF4825 PF16107.5 OIR55641.1 - 0.08 13.1 0.6 10 6.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4825) ABC_tran PF00005.27 OIR55644.1 - 0.092 13.3 0.0 0.1 13.1 0.0 1.3 1 1 0 1 1 1 0 ABC transporter SEO_C PF14577.6 OIR55645.1 - 0.0041 16.6 0.2 0.0045 16.5 0.2 1.1 1 0 0 1 1 1 1 Sieve element occlusion C-terminus IL3Ra_N PF18611.1 OIR55646.1 - 0.11 12.5 0.8 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 IL-3 receptor alpha chain N-terminal domain zf-C3HC4_3 PF13920.6 OIR55647.1 - 3.4e-06 26.8 8.3 5.9e-06 26.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55647.1 - 3e-05 24.1 6.3 3.8e-05 23.7 5.5 1.5 2 0 0 2 2 2 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR55647.1 - 0.002 18.4 6.8 0.0029 17.8 6.8 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_10 PF16685.5 OIR55647.1 - 0.0097 16.0 4.6 0.019 15.1 4.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OIR55647.1 - 0.015 15.1 12.2 0.098 12.5 4.1 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OIR55647.1 - 0.033 14.2 6.7 2.4 8.2 7.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon Stc1 PF12898.7 OIR55647.1 - 0.038 14.5 6.9 0.098 13.2 2.3 2.3 2 1 0 2 2 2 0 Stc1 domain zf-RING_UBOX PF13445.6 OIR55647.1 - 0.15 12.1 2.3 0.22 11.6 1.5 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OIR55647.1 - 0.21 11.6 8.6 0.39 10.7 8.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-BED PF02892.15 OIR55647.1 - 0.22 11.6 7.8 12 6.0 0.0 3.3 2 1 1 3 3 3 0 BED zinc finger OrfB_Zn_ribbon PF07282.11 OIR55647.1 - 0.35 10.8 4.0 0.89 9.5 2.2 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-Di19 PF05605.12 OIR55647.1 - 0.45 10.8 0.3 0.45 10.8 0.3 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.6 OIR55647.1 - 0.48 10.6 9.1 1.4 9.2 7.6 2.4 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING Rhodanese_C PF12368.8 OIR55647.1 - 0.61 10.5 7.4 2 8.8 7.4 1.9 1 1 0 1 1 1 0 Rhodanase C-terminal DUF4451 PF14616.6 OIR55647.1 - 2.3 8.4 9.0 0.95 9.7 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) DUF2197 PF09963.9 OIR55647.1 - 4.4 7.6 10.0 21 5.5 9.7 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) EXOSC1 PF10447.9 OIR55648.1 - 2.1e-05 25.1 0.3 0.095 13.3 0.0 2.6 1 1 2 3 3 3 2 Exosome component EXOSC1/CSL4 Cas_Cas4 PF01930.17 OIR55648.1 - 0.053 13.6 3.4 2.6 8.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF83 DUF3660 PF12398.8 OIR55648.1 - 0.11 12.6 1.2 8.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Receptor serine/threonine kinase Shugoshin_N PF07558.11 OIR55648.1 - 1.2 9.0 7.5 37 4.3 0.1 3.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Sep15_SelM PF08806.11 OIR55649.1 - 2.1e-06 27.8 5.6 0.077 13.2 0.1 3.1 3 0 0 3 3 3 3 Sep15/SelM redox domain EIF_2_alpha PF07541.12 OIR55649.1 - 0.014 15.5 0.4 5.5 7.1 0.0 2.8 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit Nucleic_acid_bd PF13820.6 OIR55649.1 - 0.044 13.6 0.3 7.6 6.4 0.0 2.2 1 1 0 2 2 2 0 Putative nucleic acid-binding region Ribosomal_S4e PF00900.20 OIR55650.1 - 0.041 13.8 0.1 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal family S4e RVT_1 PF00078.27 OIR55651.1 - 2.8e-07 30.3 0.0 3.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bac_luciferase PF00296.20 OIR55652.1 - 0.0064 15.9 0.0 0.0077 15.7 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sep15_SelM PF08806.11 OIR55653.1 - 0.0029 17.7 0.2 1 9.6 0.0 2.2 2 0 0 2 2 2 2 Sep15/SelM redox domain She2p PF11435.8 OIR55655.1 - 0.0094 15.6 0.3 2.5 7.7 0.0 2.1 1 1 1 2 2 2 2 RNA binding protein She2p DUF3730 PF12530.8 OIR55655.1 - 0.12 11.9 0.1 9.2 5.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3730) DUF3409 PF11889.8 OIR55655.1 - 0.25 11.3 1.7 15 5.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3409) RVT_1 PF00078.27 OIR55661.1 - 0.00059 19.4 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OIR55667.1 - 0.15 12.3 0.1 0.25 11.5 0.1 1.5 1 1 0 1 1 1 0 Integrase core domain ADAM_spacer1 PF05986.14 OIR55668.1 - 0.039 14.0 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 DUF5089 PF17002.5 OIR55669.1 - 0.0024 17.8 4.1 0.0029 17.5 4.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) DUF553 PF04473.12 OIR55670.1 - 0.099 12.2 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Transglutaminase-like domain End_tail_spike PF12219.8 OIR55672.1 - 0.21 11.6 0.0 4.5 7.3 0.0 2.1 1 1 0 2 2 2 0 Catalytic domain of bacteriophage endosialidase SR-25 PF10500.9 OIR55673.1 - 0.11 12.1 0.1 1.9 8.0 0.0 2.0 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein LTXXQ PF07813.12 OIR55673.1 - 0.12 13.1 0.0 23 5.8 0.0 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein MafB19-deam PF14437.6 OIR55674.1 - 0.03 14.1 0.2 0.4 10.4 0.0 2.4 2 1 1 3 3 3 0 MafB19-like deaminase BAF250_C PF12031.8 OIR55674.1 - 0.042 13.2 0.1 8.9 5.5 0.0 2.8 2 1 1 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa Glyco_transf_17 PF04724.13 OIR55674.1 - 0.06 12.4 0.1 0.52 9.3 0.1 1.9 1 1 1 2 2 2 0 Glycosyltransferase family 17 ICAT PF06384.11 OIR55674.1 - 0.12 12.6 0.1 22 5.4 0.0 2.2 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Sep15_SelM PF08806.11 OIR55676.1 - 0.094 12.9 0.1 2 8.7 0.0 2.2 2 0 0 2 2 2 0 Sep15/SelM redox domain BAF250_C PF12031.8 OIR55677.1 - 0.024 13.9 0.0 4.8 6.4 0.0 2.1 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa DUF1447 PF07288.11 OIR55678.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) CdiI_4 PF18624.1 OIR55679.1 - 0.034 14.6 0.0 0.075 13.5 0.0 1.5 1 1 1 2 2 2 0 CDI immunity protein Glyco_hydro_63 PF03200.16 OIR55679.1 - 0.085 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain SEO_C PF14577.6 OIR55680.1 - 0.015 14.8 0.1 0.018 14.5 0.1 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Tombus_P33 PF08500.10 OIR55681.1 - 0.026 14.5 1.5 0.046 13.7 1.4 1.5 1 1 0 1 1 1 0 Tombusvirus p33 TnpV PF14198.6 OIR55682.1 - 0.00044 20.2 2.2 0.65 10.0 0.1 3.1 2 1 1 3 3 3 2 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR55682.1 - 0.00055 19.8 0.4 22 5.7 0.0 3.9 3 2 1 4 4 4 0 Two component regulator propeller Imm58 PF15581.6 OIR55682.1 - 0.0097 16.0 0.6 9.1 6.4 0.0 3.0 3 0 0 3 3 3 1 Immunity protein 58 Nucleic_acid_bd PF13820.6 OIR55682.1 - 0.011 15.6 0.6 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Putative nucleic acid-binding region UPF0228 PF05727.11 OIR55682.1 - 0.027 14.3 1.3 0.2 11.5 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0228) Nuc_sug_transp PF04142.15 OIR55682.1 - 0.075 12.2 0.8 17 4.4 0.0 2.9 3 0 0 3 3 3 0 Nucleotide-sugar transporter DUF4479 PF14794.6 OIR55682.1 - 0.081 12.8 0.2 12 5.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4479) DUF1125 PF06563.11 OIR55682.1 - 0.1 12.5 1.7 66 3.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1125) DUF3860 PF12976.7 OIR55682.1 - 0.2 11.7 0.8 22 5.2 0.0 2.9 2 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) zf-C3HC4_3 PF13920.6 OIR55684.1 - 0.0054 16.6 6.2 0.0054 16.6 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55684.1 - 0.026 14.6 4.3 0.053 13.6 3.4 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 OIR55684.1 - 0.85 9.5 8.3 1.8 8.4 0.3 3.4 3 1 1 4 4 4 0 RING/Ubox like zinc-binding domain DUF2197 PF09963.9 OIR55684.1 - 1 9.6 10.2 1.8 8.9 6.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Exo_endo_phos_2 PF14529.6 OIR55687.1 - 0.0052 16.6 0.0 0.0075 16.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OIR55687.1 - 0.026 14.0 0.0 0.055 13.0 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family FB_lectin PF07367.11 OIR55690.1 - 0.07 13.1 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal fruit body lectin Nuc_sug_transp PF04142.15 OIR55692.1 - 0.00041 19.6 0.2 0.19 10.9 0.2 2.8 2 1 1 3 3 3 2 Nucleotide-sugar transporter Reg_prop PF07494.11 OIR55692.1 - 0.015 15.4 0.1 46 4.7 0.0 3.3 3 0 0 3 3 3 0 Two component regulator propeller Nucleic_acid_bd PF13820.6 OIR55692.1 - 0.02 14.7 1.6 9.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Putative nucleic acid-binding region Spt20 PF12090.8 OIR55692.1 - 0.091 12.4 0.8 0.11 12.1 0.8 1.1 1 0 0 1 1 1 0 Spt20 family RVT_1 PF00078.27 OIR55694.1 - 0.0022 17.5 0.1 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OIR55695.1 - 4.9e-06 26.2 0.0 7.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpa2_4 PF06883.12 OIR55695.1 - 0.0089 16.0 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain Antimicrobial12 PF08107.11 OIR55695.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Pleurocidin family Presenilin PF01080.17 OIR55697.1 - 0.37 9.5 2.4 0.42 9.3 2.4 1.0 1 0 0 1 1 1 0 Presenilin HGTP_anticodon2 PF12745.7 OIR55697.1 - 0.43 10.0 5.9 0.5 9.8 5.9 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CgtA PF06306.11 OIR55699.1 - 0.042 13.3 0.0 0.044 13.2 0.0 1.0 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) DUF2247 PF10004.9 OIR55702.1 - 0.0027 17.5 0.5 0.1 12.4 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2247) BAF250_C PF12031.8 OIR55702.1 - 0.0055 16.0 0.0 0.73 9.1 0.0 2.7 1 1 2 3 3 3 1 SWI/SNF-like complex subunit BAF250/Osa Gryzun-like PF12742.7 OIR55702.1 - 0.026 14.5 1.5 5.2 7.1 0.0 3.6 3 1 0 3 3 3 0 Gryzun, putative Golgi trafficking DUF4833 PF16117.5 OIR55702.1 - 0.05 13.6 0.4 9.6 6.2 0.1 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4833) PrgU PF09627.10 OIR55702.1 - 0.21 11.6 1.5 12 5.9 0.0 2.6 1 1 2 3 3 3 0 PrgU-like protein DUF2333 PF10095.9 OIR55704.1 - 0.055 12.5 0.2 0.068 12.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) RVT_1 PF00078.27 OIR55705.1 - 1.1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3060 PF11259.8 OIR55707.1 - 0.12 12.0 0.3 26 4.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3060) MlaD PF02470.20 OIR55707.1 - 0.15 12.3 0.0 8.9 6.7 0.0 2.9 2 1 0 2 2 2 0 MlaD protein Sh_2 PF17512.2 OIR55708.1 - 0.064 13.0 0.0 5 6.9 0.0 2.4 2 1 1 3 3 3 0 Metapneumovirus Small hydrophobic protein CCDC32 PF14989.6 OIR55713.1 - 0.091 12.8 0.4 3.4 7.6 0.4 2.1 1 1 0 1 1 1 0 Coiled-coil domain containing 32 AAA_23 PF13476.6 OIR55715.1 - 0.043 14.3 2.5 0.047 14.2 2.5 1.1 1 0 0 1 1 1 0 AAA domain HHH_3 PF12836.7 OIR55717.1 - 0.12 12.7 0.2 0.2 11.9 0.2 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif ATP-synt_DE_N PF02823.16 OIR55718.1 - 0.01 15.7 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Hairy_orange PF07527.13 OIR55718.1 - 0.031 14.5 0.1 0.06 13.6 0.1 1.4 1 0 0 1 1 1 0 Hairy Orange rve PF00665.26 OIR55719.1 - 5.6e-05 23.3 0.2 0.00013 22.1 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR55719.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF3253 PF11625.8 OIR55720.1 - 0.051 13.8 0.0 0.075 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) YacG PF03884.14 OIR55721.1 - 2e-07 30.6 0.0 1.4 8.7 0.0 4.3 4 0 0 4 4 4 4 DNA gyrase inhibitor YacG RE_EcoO109I PF14511.6 OIR55721.1 - 0.0046 16.6 0.1 6.3 6.3 0.0 3.1 2 1 1 3 3 3 2 Type II restriction endonuclease EcoO109I SCAB-Ig PF16709.5 OIR55721.1 - 0.0054 16.8 0.0 0.97 9.5 0.0 3.3 1 1 2 4 4 4 1 Ig domain of plant-specific actin-binding protein MlaD PF02470.20 OIR55721.1 - 0.0071 16.6 0.0 19 5.6 0.0 3.4 4 0 0 4 4 4 1 MlaD protein FHA_2 PF17913.1 OIR55721.1 - 0.039 14.2 0.0 56 4.1 0.0 3.7 4 0 0 4 4 4 0 FHA domain SOR PF07682.11 OIR55721.1 - 0.07 12.0 0.0 3.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Sulphur oxygenase reductase RVT_1 PF00078.27 OIR55722.1 - 6.6e-26 91.2 0.0 6.9e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) QSOX_Trx1 PF18108.1 OIR55723.1 - 0.067 13.4 0.1 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 QSOX Trx-like domain ECSIT PF06239.11 OIR55723.1 - 0.074 12.2 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway ANAPC15 PF15243.6 OIR55723.1 - 0.18 12.2 0.4 25 5.4 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 Dcc1 PF09724.9 OIR55724.1 - 0.038 13.3 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 DUF218 PF02698.17 OIR55724.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain DUF4698 PF15769.5 OIR55726.1 - 0.13 11.3 5.2 0.17 10.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Clostridium_P47 PF06597.11 OIR55729.1 - 0.023 13.4 0.0 0.025 13.3 0.0 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein Trypan_PARP PF05887.11 OIR55729.1 - 0.036 14.1 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) UCMA PF17085.5 OIR55729.1 - 3.2 7.8 9.6 0.26 11.3 3.1 2.3 2 2 1 3 3 3 0 Unique cartilage matrix associated protein ID PF18543.1 OIR55730.1 - 0.0086 16.1 0.0 5.1 7.2 0.0 2.4 2 0 0 2 2 2 2 Intracellular delivery domain Pkinase PF00069.25 OIR55731.1 - 4.6e-22 78.6 2.4 5.7e-22 78.3 2.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55731.1 - 1.2e-14 54.3 0.6 1.5e-14 54.0 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OIR55731.1 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OIR55731.1 - 0.0014 18.1 0.2 0.0017 17.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_10 PF16685.5 OIR55731.1 - 0.054 13.6 0.7 0.11 12.7 0.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Choline_kinase PF01633.20 OIR55731.1 - 0.065 12.8 0.2 1.5 8.4 0.2 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OIR55731.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 OIR55732.1 - 8.1e-06 25.6 6.5 1.4e-05 24.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ZapB PF06005.12 OIR55732.1 - 0.052 14.0 0.1 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 Cell division protein ZapB DZR PF12773.7 OIR55732.1 - 0.15 12.1 7.5 3.3 7.8 7.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 OIR55732.1 - 0.19 11.6 8.6 2.9 7.7 8.7 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR55732.1 - 1.2 9.1 9.0 8.6 6.4 8.6 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zinc_ribbon_9 PF14369.6 OIR55732.1 - 1.4 9.2 6.5 19 5.6 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbon zf-C3HC4_4 PF15227.6 OIR55732.1 - 1.9 8.7 7.9 0.7 10.1 3.2 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING NOB1_Zn_bind PF08772.11 OIR55732.1 - 2 8.6 6.7 2 8.6 3.1 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-CHY PF05495.12 OIR55732.1 - 2.5 8.6 8.2 14 6.2 8.1 2.0 1 1 0 1 1 1 0 CHY zinc finger zinc-ribbons_6 PF07191.12 OIR55732.1 - 4.4 7.4 9.3 64 3.6 9.3 2.3 1 1 0 1 1 1 0 zinc-ribbons Sh_2 PF17512.2 OIR55733.1 - 0.0053 16.6 0.4 0.65 9.8 0.1 2.5 1 1 2 3 3 3 2 Metapneumovirus Small hydrophobic protein DUF3942 PF13078.6 OIR55733.1 - 0.056 13.7 0.4 13 6.1 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3942) RNA_pol_Rpb4 PF03874.16 OIR55736.1 - 0.083 13.2 0.2 0.16 12.3 0.2 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb4 Integrase_H2C2 PF17921.1 OIR55737.1 - 0.034 14.3 0.1 0.11 12.6 0.1 1.8 1 1 0 1 1 1 0 Integrase zinc binding domain zf_Rg PF17915.1 OIR55737.1 - 0.058 12.8 0.9 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger Chromo_2 PF18704.1 OIR55740.1 - 0.0041 17.4 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin organization modifier domain 2 Exo_endo_phos PF03372.23 OIR55742.1 - 4e-05 23.3 0.0 6.4e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR55742.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Sep15_SelM PF08806.11 OIR55743.1 - 6.8e-05 23.0 2.5 0.13 12.4 0.1 3.3 3 0 0 3 3 3 2 Sep15/SelM redox domain Unpaired PF15972.5 OIR55743.1 - 0.0061 16.1 0.6 2.1 7.8 0.0 2.5 1 1 2 3 3 3 2 Unpaired protein DUF2714 PF10896.8 OIR55743.1 - 0.0078 16.3 6.9 0.18 11.9 0.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF2714) ANAPC15 PF15243.6 OIR55743.1 - 0.0089 16.4 1.9 0.38 11.2 0.2 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 15 NBD94 PF16830.5 OIR55743.1 - 0.031 14.6 11.3 4.8 7.6 1.4 3.2 1 1 2 3 3 3 0 Nucleotide-Binding Domain 94 of RH Reg_prop PF07494.11 OIR55743.1 - 0.039 14.2 0.6 24 5.6 0.0 3.0 3 0 0 3 3 3 0 Two component regulator propeller Cas_Cas4 PF01930.17 OIR55743.1 - 0.24 11.5 4.6 12 6.0 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function DUF83 Sep15_SelM PF08806.11 OIR55745.1 - 0.0005 20.2 4.8 0.21 11.7 0.2 4.0 2 1 0 4 4 4 2 Sep15/SelM redox domain GcrA PF07750.11 OIR55745.1 - 0.013 15.9 0.3 37 4.7 0.0 3.2 2 1 0 3 3 3 0 GcrA cell cycle regulator zf-C3HC4_3 PF13920.6 OIR55746.1 - 0.037 13.9 1.5 0.053 13.4 1.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3929 PF13066.6 OIR55746.1 - 0.085 12.9 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) PPTA PF01239.22 OIR55747.1 - 0.0022 17.7 1.1 1.9 8.3 0.1 2.5 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat ANAPC15 PF15243.6 OIR55747.1 - 0.0061 16.9 1.1 3.3 8.2 0.1 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 15 TMEM191C PF15194.6 OIR55747.1 - 0.0064 16.7 0.0 10 6.3 0.0 3.0 1 1 1 3 3 3 2 TMEM191C family BAF250_C PF12031.8 OIR55747.1 - 0.021 14.1 0.0 0.89 8.8 0.0 2.4 1 1 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa TbpB_C PF17483.2 OIR55747.1 - 0.048 14.0 0.0 3.1 8.2 0.0 2.7 1 1 2 3 3 3 0 C-lobe handle domain of Tf-binding protein B DUF3269 PF11673.8 OIR55747.1 - 0.18 12.2 0.8 28 5.2 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3269) Sep15_SelM PF08806.11 OIR55749.1 - 5e-05 23.4 2.3 0.34 11.1 0.0 3.9 4 0 0 4 4 4 3 Sep15/SelM redox domain MazE_antitoxin PF04014.18 OIR55749.1 - 0.85 9.6 2.6 32 4.6 0.1 3.5 4 0 0 4 4 4 0 Antidote-toxin recognition MazE, bacterial antitoxin MlaD PF02470.20 OIR55750.1 - 0.0029 17.9 0.0 4.8 7.6 0.0 3.7 3 1 0 4 4 4 1 MlaD protein DUF4833 PF16117.5 OIR55750.1 - 0.016 15.2 0.1 0.025 14.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4833) ANAPC15 PF15243.6 OIR55750.1 - 0.58 10.6 4.3 7.3 7.1 0.3 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 ATP-grasp_6 PF18419.1 OIR55752.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp-like domain zf-C3HC4_3 PF13920.6 OIR55753.1 - 0.085 12.7 5.3 0.15 11.9 5.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3795 PF12675.7 OIR55753.1 - 0.096 13.1 4.2 2 8.9 4.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Reg_prop PF07494.11 OIR55757.1 - 7e-05 22.6 0.0 16 6.2 0.0 3.6 3 0 0 3 3 3 3 Two component regulator propeller TnpV PF14198.6 OIR55757.1 - 0.0013 18.7 4.9 2.5 8.1 0.2 3.1 1 1 2 3 3 3 3 Transposon-encoded protein TnpV ANAPC15 PF15243.6 OIR55757.1 - 0.0068 16.8 3.1 2.8 8.4 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 15 Fungal_TACC PF12709.7 OIR55757.1 - 0.012 16.0 2.4 0.21 12.0 0.1 2.9 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins UvsY PF11056.8 OIR55757.1 - 0.021 15.2 1.1 0.14 12.5 0.2 1.9 1 1 1 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY Nucleic_acid_bd PF13820.6 OIR55757.1 - 0.052 13.4 1.1 3.1 7.6 0.1 2.8 2 1 1 3 3 3 0 Putative nucleic acid-binding region Lectin_C PF00059.21 OIR55757.1 - 0.09 13.5 1.3 23 5.8 0.1 3.0 2 1 0 3 3 3 0 Lectin C-type domain DUF1125 PF06563.11 OIR55757.1 - 0.15 11.9 1.3 73 3.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1125) MafB19-deam PF14437.6 OIR55757.1 - 0.24 11.2 2.2 4 7.2 0.1 2.7 2 1 1 3 3 3 0 MafB19-like deaminase Pkinase PF00069.25 OIR55758.1 - 8.8e-11 41.7 0.4 1e-10 41.5 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55758.1 - 8.6e-05 21.9 0.1 0.00011 21.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1132 PF06575.12 OIR55759.1 - 0.9 10.0 3.4 1.9 8.9 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1132) MEF2_binding PF09047.10 OIR55761.1 - 0.056 13.3 0.2 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 MEF2 binding YacG PF03884.14 OIR55762.1 - 0.003 17.3 0.0 1.9 8.3 0.0 3.0 3 0 0 3 3 3 2 DNA gyrase inhibitor YacG BAF250_C PF12031.8 OIR55763.1 - 1.7e-06 27.5 0.3 0.0004 19.8 0.0 2.4 2 1 0 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa DUF4682 PF15733.5 OIR55763.1 - 0.0013 19.4 0.8 18 6.0 0.0 3.8 2 1 2 4 4 4 2 Domain of unknown function (DUF4682) NOC3p PF07540.11 OIR55763.1 - 0.014 15.8 0.3 3 8.4 0.0 3.0 1 1 1 3 3 3 0 Nucleolar complex-associated protein Sep15_SelM PF08806.11 OIR55763.1 - 0.026 14.7 6.0 1.9 8.7 1.7 3.3 3 1 0 3 3 3 0 Sep15/SelM redox domain DUF2247 PF10004.9 OIR55763.1 - 0.71 9.6 9.4 0.47 10.2 1.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) zf-C3HC4_3 PF13920.6 OIR55770.1 - 9.1e-06 25.4 7.3 1.5e-05 24.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55770.1 - 0.0006 19.9 5.0 0.0012 19.0 5.0 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR55770.1 - 0.0019 18.4 6.5 0.003 17.8 6.5 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR55770.1 - 0.011 15.5 7.8 0.21 11.4 1.9 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR55770.1 - 0.013 15.5 6.5 0.015 15.3 5.6 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Stc1 PF12898.7 OIR55770.1 - 0.03 14.8 5.2 0.25 11.9 2.1 2.3 2 0 0 2 2 2 0 Stc1 domain Zn_Tnp_IS1595 PF12760.7 OIR55770.1 - 0.041 13.9 1.7 0.092 12.7 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 OIR55770.1 - 0.097 12.7 5.4 3.1 7.9 6.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 OIR55770.1 - 0.24 11.7 8.9 0.33 11.3 2.8 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 OIR55770.1 - 0.34 11.0 6.6 4.2 7.5 0.1 2.9 2 1 1 3 3 3 0 BED zinc finger PH PF00169.29 OIR55770.1 - 0.36 11.4 2.2 18 5.9 0.2 2.5 1 1 1 2 2 2 0 PH domain HypA PF01155.19 OIR55770.1 - 0.59 10.2 8.1 28 4.8 7.8 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2197 PF09963.9 OIR55770.1 - 0.88 9.9 8.7 0.98 9.7 5.5 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF4451 PF14616.6 OIR55770.1 - 1.2 9.4 6.8 0.68 10.1 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-4CXXC_R1 PF10497.9 OIR55770.1 - 1.3 9.3 6.5 3 8.1 6.5 1.7 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_4 PF15227.6 OIR55770.1 - 2.7 8.2 8.2 8.2 6.7 6.6 2.5 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING rve PF00665.26 OIR55771.1 - 1e-22 80.5 0.0 2.9e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OIR55771.1 - 1.6e-06 27.8 0.0 4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1617 PF07761.12 OIR55771.1 - 0.11 12.5 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Reg_prop PF07494.11 OIR55772.1 - 1.6e-07 30.7 1.3 1.9 9.0 0.1 4.6 4 1 0 4 4 4 3 Two component regulator propeller DUF1125 PF06563.11 OIR55772.1 - 0.0014 18.5 3.8 16 5.5 0.0 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1125) Nucleic_acid_bd PF13820.6 OIR55772.1 - 0.003 17.4 0.7 8.3 6.2 0.0 3.8 4 0 0 4 4 4 1 Putative nucleic acid-binding region DUF3860 PF12976.7 OIR55772.1 - 0.0079 16.2 0.0 11 6.1 0.0 3.4 4 0 0 4 4 4 2 Domain of Unknown Function with PDB structure (DUF3860) Sep15_SelM PF08806.11 OIR55772.1 - 0.011 15.9 1.2 1.7 8.8 0.1 2.8 3 0 0 3 3 3 0 Sep15/SelM redox domain TnpV PF14198.6 OIR55772.1 - 0.012 15.6 0.6 6.7 6.7 0.0 3.9 4 0 0 4 4 4 0 Transposon-encoded protein TnpV Nuc_sug_transp PF04142.15 OIR55772.1 - 0.019 14.1 9.2 1.8 7.7 0.1 3.8 2 1 2 4 4 4 0 Nucleotide-sugar transporter rve PF00665.26 OIR55775.1 - 9.1e-13 48.4 0.0 1.8e-12 47.5 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OIR55775.1 - 9.3e-07 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OIR55778.1 - 0.00048 20.2 0.2 0.001 19.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OIR55778.1 - 0.017 15.3 0.3 0.052 13.8 0.3 1.9 1 1 0 1 1 1 0 H2C2 zinc finger LRR_6 PF13516.6 OIR55779.1 - 1.7e-05 24.5 4.3 0.19 11.9 0.1 4.5 5 0 0 5 5 5 3 Leucine Rich repeat Borrelia_P83 PF05262.11 OIR55780.1 - 2 6.8 9.8 2.3 6.6 9.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3253 PF11625.8 OIR55783.1 - 0.05 13.8 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Sigma70_ner PF04546.13 OIR55784.1 - 0.086 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-RVT PF13966.6 OIR55785.1 - 0.00046 20.9 1.2 0.0019 18.9 1.2 2.2 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase OrfB_Zn_ribbon PF07282.11 OIR55785.1 - 0.015 15.2 1.1 0.03 14.2 1.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Sigma_1s PF02454.16 OIR55786.1 - 0.0085 16.1 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 2 Sigma 1s protein NikR_C PF08753.11 OIR55786.1 - 0.019 15.1 0.1 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 NikR C terminal nickel binding domain DUF2161 PF09929.9 OIR55787.1 - 0.051 13.7 0.2 0.084 13.0 0.2 1.5 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) DUF5071 PF16804.5 OIR55787.1 - 0.15 12.3 0.9 19 5.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5071) POX PF07526.11 OIR55787.1 - 0.44 11.1 2.9 0.63 10.6 2.9 1.3 1 1 0 1 1 1 0 Associated with HOX Integrase_H2C2 PF17921.1 OIR55788.1 - 0.00048 20.2 0.2 0.001 19.1 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OIR55788.1 - 0.017 15.3 0.3 0.052 13.8 0.3 1.9 1 1 0 1 1 1 0 H2C2 zinc finger zf-SAP30 PF13866.6 OIR55789.1 - 0.0013 18.8 0.0 0.11 12.6 0.0 3.2 3 0 0 3 3 3 1 SAP30 zinc-finger Sep15_SelM PF08806.11 OIR55789.1 - 0.029 14.5 0.2 7.8 6.7 0.0 3.3 4 0 0 4 4 4 0 Sep15/SelM redox domain Antimicrobial22 PF16047.5 OIR55789.1 - 4.4 7.3 5.5 79 3.3 0.2 3.5 3 0 0 3 3 3 0 Frog antimicrobial peptide DUF3545 PF12065.8 OIR55791.1 - 0.006 16.6 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3545) zf-RVT PF13966.6 OIR55791.1 - 0.026 15.2 0.0 0.058 14.1 0.0 1.6 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Imm3 PF14425.6 OIR55795.1 - 0.059 13.4 0.6 4.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 Pkinase PF00069.25 OIR55797.1 - 8.7e-05 22.0 0.1 0.00029 20.3 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 OIR55800.1 - 7e-05 22.6 4.2 0.00013 21.8 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR55800.1 - 0.0006 19.6 1.8 0.0011 18.7 1.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR55800.1 - 0.0075 16.0 3.8 0.056 13.2 4.5 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OIR55800.1 - 0.014 15.5 3.2 0.028 14.5 3.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR55800.1 - 0.02 15.2 5.4 0.026 14.8 4.5 1.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 OIR55800.1 - 0.028 14.3 2.0 0.067 13.1 2.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OIR55800.1 - 0.028 14.3 0.8 0.047 13.6 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 OIR55800.1 - 0.16 12.0 4.8 0.2 11.6 2.2 2.1 1 1 1 2 2 2 0 zinc-ribbons zf-RING_UBOX PF13445.6 OIR55800.1 - 1.5 8.9 4.7 2.1 8.5 1.6 2.7 2 1 0 2 2 2 0 RING-type zinc-finger DUF1297 PF06973.12 OIR55801.1 - 0.054 13.0 0.1 0.084 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) RdRP_1 PF00680.20 OIR55802.1 - 0.0084 14.7 0.2 0.011 14.2 0.2 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ADD_DNMT3 PF17980.1 OIR55805.1 - 5.6e-06 26.2 1.8 5.4 7.1 0.0 4.5 4 0 0 4 4 4 4 Cysteine rich ADD domain in DNMT3 zf-C3HC4_3 PF13920.6 OIR55806.1 - 7e-05 22.6 10.5 0.00011 22.0 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR55806.1 - 0.043 13.8 8.5 0.094 12.7 8.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OIR55806.1 - 0.064 13.6 11.1 0.1 12.9 11.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_10 PF16685.5 OIR55806.1 - 0.22 11.7 7.6 0.37 11.0 7.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-nanos PF05741.13 OIR55806.1 - 7.6 6.9 13.2 2.3 8.5 1.2 3.1 1 1 2 3 3 3 0 Nanos RNA binding domain Integrase_H2C2 PF17921.1 OIR55807.1 - 0.045 13.8 0.4 0.074 13.2 0.4 1.4 1 0 0 1 1 1 0 Integrase zinc binding domain LolA PF03548.15 OIR55808.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA tRNA_deacylase PF04414.12 OIR55809.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase PAGK PF15284.6 OIR55810.1 - 0.04 13.8 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Phage-encoded virulence factor Ald_Xan_dh_C PF01315.22 OIR55811.1 - 0.095 13.1 0.1 73 3.8 0.0 3.1 2 1 1 3 3 3 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain GET2 PF08690.10 OIR55812.1 - 0.11 12.2 4.8 0.12 12.0 4.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TMEM252 PF15664.5 OIR55812.1 - 0.58 9.9 3.6 3.5 7.4 0.1 2.1 1 1 1 2 2 2 0 Transmembrane protein 252 family Presenilin PF01080.17 OIR55812.1 - 1.3 7.7 4.6 1.6 7.4 4.6 1.1 1 0 0 1 1 1 0 Presenilin OFCC1 PF15680.5 OIR55815.1 - 0.015 15.9 1.0 0.035 14.7 1.0 1.6 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein zf-C3HC PF07967.13 OIR55815.1 - 0.096 12.7 0.4 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 C3HC zinc finger-like SWIRM-assoc_1 PF16495.5 OIR55815.1 - 3.3 7.8 11.0 0.065 13.2 2.3 2.6 2 1 0 3 3 3 0 SWIRM-associated region 1 LMBR1 PF04791.16 OIR55816.1 - 0.01 14.8 0.8 0.011 14.7 0.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein LUC7 PF03194.15 OIR55816.1 - 0.072 12.7 1.0 0.08 12.6 1.0 1.0 1 0 0 1 1 1 0 LUC7 N_terminus Enkurin PF13864.6 OIR55816.1 - 0.08 13.4 2.8 0.13 12.7 2.8 1.3 1 0 0 1 1 1 0 Calmodulin-binding DUF4250 PF14056.6 OIR55816.1 - 0.11 12.5 1.3 0.65 10.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Chromo_2 PF18704.1 OIR55817.1 - 0.027 14.7 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 DUF4382 PF14321.6 OIR55817.1 - 0.044 14.0 0.0 0.083 13.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4382) DUF4817 PF16087.5 OIR55820.1 - 0.027 14.3 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DUF1308 PF07000.11 OIR55821.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) zf-RVT PF13966.6 OIR55822.1 - 0.0012 19.5 0.2 0.0025 18.5 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3545 PF12065.8 OIR55822.1 - 0.012 15.6 0.2 0.05 13.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) zf-RVT PF13966.6 OIR55823.1 - 0.00045 20.9 1.2 0.0019 18.9 1.2 2.2 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase OrfB_Zn_ribbon PF07282.11 OIR55823.1 - 0.014 15.3 1.1 0.028 14.3 1.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DNA_binding_1 PF01035.20 OIR55824.1 - 0.084 13.0 0.2 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain CENP-B_N PF04218.13 OIR55824.1 - 0.15 11.7 1.0 9.1 6.0 0.0 3.0 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain DUF3160 PF11369.8 OIR55825.1 - 0.11 11.0 0.0 0.27 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3160) Pkinase PF00069.25 OIR55827.1 - 3e-10 39.9 0.5 5.9e-10 38.9 0.4 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55827.1 - 5.2e-07 29.2 0.1 9.1e-07 28.4 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1323 PF07037.11 OIR55829.1 - 0.024 15.0 1.9 1.7 9.0 0.1 2.6 2 1 1 3 3 3 0 Putative transcription regulator (DUF1323) MbeB_N PF04837.12 OIR55829.1 - 0.2 12.0 2.3 37 4.7 0.1 3.4 3 0 0 3 3 3 0 MbeB-like, N-term conserved region rve PF00665.26 OIR55832.1 - 1.3e-21 77.0 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR55832.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_IS240 PF13610.6 OIR55832.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 DDE domain YacG PF03884.14 OIR55834.1 - 0.00018 21.2 0.0 1.1 9.1 0.0 4.4 5 0 0 5 5 5 1 DNA gyrase inhibitor YacG BAF250_C PF12031.8 OIR55834.1 - 0.0053 16.1 0.2 0.019 14.3 0.1 1.9 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa SpoIID PF08486.10 OIR55834.1 - 0.0077 16.8 0.2 23 5.7 0.0 3.7 4 0 0 4 4 4 2 Stage II sporulation protein DUF1195 PF06708.11 OIR55834.1 - 0.016 15.0 0.0 45 3.8 0.0 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF1195) MlaD PF02470.20 OIR55834.1 - 0.066 13.5 0.0 36 4.8 0.0 3.4 3 1 0 3 3 3 0 MlaD protein Rcd1 PF04078.13 OIR55834.1 - 0.074 12.3 0.1 0.78 9.0 0.0 2.1 1 1 1 2 2 2 0 Cell differentiation family, Rcd1-like MRP-S35 PF10246.9 OIR55834.1 - 0.14 12.1 0.1 2.6 8.1 0.0 2.8 3 1 1 4 4 4 0 Mitochondrial ribosomal protein MRP-S35 zf-RAG1 PF10426.9 OIR55835.1 - 0.028 14.5 0.4 0.07 13.3 0.4 1.7 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain TnpV PF14198.6 OIR55836.1 - 0.0086 16.0 3.4 0.4 10.7 0.1 3.3 1 1 1 3 3 3 1 Transposon-encoded protein TnpV Nuc_sug_transp PF04142.15 OIR55836.1 - 0.048 12.8 0.4 0.76 8.9 0.0 2.3 2 1 1 3 3 3 0 Nucleotide-sugar transporter FlhD PF05247.13 OIR55836.1 - 0.058 13.7 0.1 2.7 8.3 0.1 2.8 4 0 0 4 4 4 0 Flagellar transcriptional activator (FlhD) DUF4385 PF14328.6 OIR55836.1 - 0.13 12.3 0.0 0.79 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4385) DUF3496 PF12001.8 OIR55838.1 - 0.12 12.7 0.6 0.31 11.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) DUF3253 PF11625.8 OIR55840.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) SEO_C PF14577.6 OIR55840.1 - 0.055 12.9 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Sieve element occlusion C-terminus TBPIP_N PF15517.6 OIR55842.1 - 0.053 13.6 0.1 0.11 12.6 0.0 1.5 2 0 0 2 2 2 0 TBP-interacting protein N-terminus DHHA1 PF02272.19 OIR55842.1 - 0.099 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 DHHA1 domain Es2 PF09751.9 OIR55844.1 - 0.055 13.2 1.4 0.063 13.0 1.4 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 TFIIA PF03153.13 OIR55844.1 - 9.2 6.1 15.9 10 6.0 15.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HMG_box_5 PF14887.6 OIR55845.1 - 0.0093 15.9 0.2 2.6 8.1 0.0 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box 5 ECSIT PF06239.11 OIR55845.1 - 0.039 13.1 0.2 4.8 6.2 0.0 3.4 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Sep15_SelM PF08806.11 OIR55845.1 - 0.042 14.0 0.2 2.9 8.1 0.0 3.5 4 0 0 4 4 4 0 Sep15/SelM redox domain GET2 PF08690.10 OIR55846.1 - 0.019 14.6 0.9 0.023 14.4 0.9 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Presenilin PF01080.17 OIR55846.1 - 2.5 6.8 3.8 3.1 6.4 3.8 1.1 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 OIR55847.1 - 0.00019 21.4 5.0 0.00033 20.6 5.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OIR55847.1 - 0.0006 19.5 4.7 0.0012 18.5 4.7 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger SWIRM-assoc_1 PF16495.5 OIR55848.1 - 0.0066 16.4 2.6 0.015 15.3 1.0 2.3 1 1 0 2 2 2 1 SWIRM-associated region 1 RVT_1 PF00078.27 OIR55849.1 - 0.04 13.4 0.0 0.047 13.2 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Nucleic_acid_bd PF13820.6 OIR55850.1 - 0.35 10.7 1.8 19 5.1 0.1 2.3 1 1 1 2 2 2 0 Putative nucleic acid-binding region Pkinase PF00069.25 OIR55851.1 - 2.6e-19 69.6 0.0 5.7e-18 65.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55851.1 - 1.3e-09 37.7 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR55851.1 - 0.00063 19.2 0.1 0.00098 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR55851.1 - 0.047 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2380 PF09533.10 OIR55852.1 - 0.067 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Sep15_SelM PF08806.11 OIR55853.1 - 0.041 14.0 1.0 2.1 8.6 0.0 3.2 3 0 0 3 3 3 0 Sep15/SelM redox domain Herpes_DNAp_acc PF04929.12 OIR55853.1 - 0.19 10.6 0.0 14 4.6 0.0 2.9 3 0 0 3 3 3 0 Herpes DNA replication accessory factor SAP18 PF06487.12 OIR55854.1 - 0.049 13.8 0.1 0.074 13.2 0.1 1.2 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) RVT_1 PF00078.27 OIR55854.1 - 0.055 13.0 0.1 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) QSOX_Trx1 PF18108.1 OIR55855.1 - 0.086 13.0 0.1 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 QSOX Trx-like domain ECSIT PF06239.11 OIR55855.1 - 0.12 11.5 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway BAF250_C PF12031.8 OIR55856.1 - 0.01 15.1 0.0 0.046 13.0 0.0 1.9 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Methyltransf_1N PF02870.15 OIR55860.1 - 0.037 14.8 0.2 7.1 7.5 0.0 3.5 4 0 0 4 4 4 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain FHA_2 PF17913.1 OIR55860.1 - 0.11 12.7 0.0 8.5 6.7 0.0 3.2 3 1 0 3 3 3 0 FHA domain DUF3263 PF11662.8 OIR55861.1 - 0.12 12.2 0.2 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3263) zf-C3HC4_3 PF13920.6 OIR55864.1 - 6.8e-05 22.6 5.1 0.00012 21.9 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55864.1 - 0.00077 19.5 2.5 0.0018 18.4 2.3 1.7 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_4 PF14570.6 OIR55864.1 - 0.032 14.0 5.7 0.36 10.6 1.5 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR55864.1 - 0.051 13.8 4.7 0.083 13.1 4.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_10 PF16685.5 OIR55864.1 - 0.058 13.5 4.2 0.1 12.7 4.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 OIR55864.1 - 0.085 13.2 6.3 0.16 12.4 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain TF_Zn_Ribbon PF08271.12 OIR55864.1 - 0.35 10.4 3.5 2.9 7.5 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4_4 PF15227.6 OIR55864.1 - 0.43 10.8 6.6 2 8.6 6.1 2.4 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING DZR PF12773.7 OIR55864.1 - 0.72 9.9 4.1 2 8.5 3.5 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 OIR55864.1 - 1.5 9.2 5.6 1.3 9.4 0.3 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FAM25 PF15825.5 OIR55867.1 - 0.075 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 FAM25 family GPHH PF16905.5 OIR55868.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated FHA_2 PF17913.1 OIR55869.1 - 0.025 14.8 0.0 3.1 8.1 0.0 2.2 2 0 0 2 2 2 0 FHA domain ANAPC15 PF15243.6 OIR55871.1 - 8.7 6.8 6.5 18 5.8 0.1 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 15 Nuc_sug_transp PF04142.15 OIR55871.1 - 9.3 5.3 6.1 14 4.7 0.1 3.0 2 2 1 3 3 3 0 Nucleotide-sugar transporter MlaD PF02470.20 OIR55872.1 - 0.0013 19.0 0.0 1.4 9.3 0.0 3.0 2 1 1 3 3 3 2 MlaD protein GcrA PF07750.11 OIR55872.1 - 0.14 12.6 0.3 6.1 7.2 0.1 2.7 1 1 2 3 3 3 0 GcrA cell cycle regulator YacG PF03884.14 OIR55873.1 - 0.00015 21.4 0.0 6.3 6.6 0.0 4.9 5 0 0 5 5 5 1 DNA gyrase inhibitor YacG SpoIID PF08486.10 OIR55873.1 - 0.0052 17.3 1.6 15 6.2 0.0 4.5 5 0 0 5 5 5 1 Stage II sporulation protein DUF1487 PF07368.11 OIR55873.1 - 0.033 13.6 0.1 1.2 8.5 0.0 3.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1487) MRP-S35 PF10246.9 OIR55873.1 - 0.036 14.0 0.3 10 6.1 0.0 3.7 2 2 2 4 4 4 0 Mitochondrial ribosomal protein MRP-S35 MlaD PF02470.20 OIR55873.1 - 0.041 14.2 0.0 22 5.4 0.0 3.9 5 0 0 5 5 5 0 MlaD protein FANCI_HD2 PF14680.6 OIR55873.1 - 0.053 12.8 0.2 7.6 5.7 0.0 2.9 2 1 0 3 3 3 0 FANCI helical domain 2 DUF1195 PF06708.11 OIR55873.1 - 0.066 13.0 0.1 41 3.9 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1195) LEDGF PF11467.8 OIR55873.1 - 0.085 12.5 0.0 1.9 8.1 0.1 2.7 2 1 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) NikR_C PF08753.11 OIR55873.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Lar_restr_allev PF14354.6 OIR55873.1 - 0.23 11.9 2.2 94 3.5 0.0 4.1 4 2 0 4 4 4 0 Restriction alleviation protein Lar KR PF08659.10 OIR55873.1 - 0.56 10.1 4.3 31 4.4 0.1 3.4 1 1 2 4 4 4 0 KR domain THOC2_N PF16134.5 OIR55874.1 - 1.4e-22 80.2 1.2 6.4e-22 78.0 0.1 2.0 1 1 0 2 2 2 1 THO complex subunit 2 N-terminus SAM_2 PF07647.17 OIR55874.1 - 0.1 12.7 0.2 0.25 11.5 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) NikR_C PF08753.11 OIR55875.1 - 0.026 14.7 0.0 0.071 13.3 0.0 1.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain NikR_C PF08753.11 OIR55877.1 - 0.096 12.9 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 NikR C terminal nickel binding domain LCIB_C_CA PF18599.1 OIR55878.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases zf-C3HC4_3 PF13920.6 OIR55880.1 - 6e-05 22.8 2.7 6e-05 22.8 2.7 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2197 PF09963.9 OIR55880.1 - 0.055 13.7 0.9 0.055 13.7 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-RING_4 PF14570.6 OIR55880.1 - 0.36 10.6 4.3 1 9.2 2.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-AD PF07776.15 OIR55880.1 - 0.58 10.4 5.4 4.7 7.5 0.8 2.2 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) Prok-RING_4 PF14447.6 OIR55883.1 - 0.00023 20.9 1.8 0.00074 19.3 1.8 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OIR55883.1 - 0.00052 19.8 2.4 0.00052 19.8 2.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OIR55883.1 - 0.0096 15.7 2.1 0.0096 15.7 2.1 2.5 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OIR55883.1 - 0.013 15.8 2.1 0.013 15.8 2.1 2.5 2 1 0 2 2 2 0 Ring finger domain Acetyltransf_CG PF14542.6 OIR55883.1 - 0.041 14.0 0.4 0.082 13.0 0.4 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Repressor_Mnt PF11423.8 OIR55884.1 - 0.081 12.7 0.1 0.78 9.6 0.0 2.2 2 0 0 2 2 2 0 Regulatory protein Mnt TnpV PF14198.6 OIR55886.1 - 0.0015 18.5 0.6 14 5.7 0.0 4.2 4 1 0 4 4 4 2 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR55886.1 - 0.0017 18.4 3.0 74 4.1 0.0 5.2 5 0 0 5 5 5 0 Two component regulator propeller DUF4385 PF14328.6 OIR55886.1 - 0.01 15.9 0.1 4.2 7.4 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4385) Sep15_SelM PF08806.11 OIR55886.1 - 0.031 14.4 0.2 5 7.4 0.1 3.5 4 0 0 4 4 4 0 Sep15/SelM redox domain MbeB_N PF04837.12 OIR55886.1 - 0.084 13.2 0.1 4.9 7.5 0.0 2.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region T2SSN PF01203.19 OIR55886.1 - 0.24 11.6 1.2 36 4.5 0.1 3.4 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein N PHM7_ext PF12621.8 OIR55888.1 - 0.00013 22.1 0.0 8.8 6.6 0.0 3.7 3 1 1 4 4 4 1 Extracellular tail, of 10TM putative phosphate transporter Dpoe2NT PF12213.8 OIR55888.1 - 0.0094 16.2 1.3 2.2 8.6 0.1 3.5 3 1 0 3 3 3 1 DNA polymerases epsilon N terminal MqsR_toxin PF15723.5 OIR55888.1 - 0.013 15.9 2.7 8.5 6.8 0.1 3.4 3 1 1 4 4 4 0 Motility quorum-sensing regulator, toxin of MqsA Ribosomal_S4e PF00900.20 OIR55888.1 - 0.049 13.5 7.8 2.7 8.0 0.1 4.2 3 1 0 5 5 5 0 Ribosomal family S4e EXOSC1 PF10447.9 OIR55888.1 - 0.053 14.1 0.2 29 5.3 0.0 3.5 2 2 2 4 4 4 0 Exosome component EXOSC1/CSL4 Reg_prop PF07494.11 OIR55888.1 - 0.063 13.5 0.0 1.4e+02 3.2 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller DUF1323 PF07037.11 OIR55888.1 - 0.18 12.2 4.3 3.8 7.9 0.4 2.6 2 1 1 3 3 3 0 Putative transcription regulator (DUF1323) DUF4825 PF16107.5 OIR55888.1 - 0.24 11.6 1.9 5.6 7.1 0.0 3.2 2 1 1 4 4 4 0 Domain of unknown function (DUF4825) RNA_ligase PF09414.10 OIR55888.1 - 1.9 8.8 4.3 2.7 8.3 0.3 2.6 2 1 1 3 3 3 0 RNA ligase Cas_Cas4 PF01930.17 OIR55888.1 - 5 7.2 9.0 13 5.8 0.4 3.7 1 1 3 4 4 4 0 Domain of unknown function DUF83 Sin3_corepress PF08295.12 OIR55888.1 - 8.7 6.5 7.2 8.4 6.5 0.1 3.4 3 1 0 4 4 4 0 Sin3 family co-repressor DUF2380 PF09533.10 OIR55889.1 - 0.0075 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) IBN_N PF03810.19 OIR55890.1 - 1e-08 34.9 1.0 1.5e-08 34.4 1.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 OIR55890.1 - 0.028 14.8 0.9 0.88 10.0 0.1 2.1 2 0 0 2 2 2 0 HEAT repeats RVT_1 PF00078.27 OIR55891.1 - 0.0055 16.2 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-SNAP50_C PF12251.8 OIR55893.1 - 0.00021 21.0 0.2 0.00036 20.3 0.2 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF4428 PF14471.6 OIR55893.1 - 0.0029 17.5 0.4 0.0082 16.0 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Ribosomal_L22e PF01776.17 OIR55893.1 - 0.028 14.8 1.0 0.69 10.3 0.2 2.4 2 0 0 2 2 2 0 Ribosomal L22e protein family YacG PF03884.14 OIR55894.1 - 0.0023 17.6 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 DNA gyrase inhibitor YacG DUF3253 PF11625.8 OIR55895.1 - 0.028 14.7 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF4382 PF14321.6 OIR55897.1 - 0.082 13.1 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) CooT PF10133.9 OIR55900.1 - 0.36 11.1 1.9 9.1 6.6 0.1 3.5 4 0 0 4 4 4 0 CO dehydrogenase accessory protein CooT RVT_1 PF00078.27 OIR55903.1 - 1.3e-11 44.4 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb1_5 PF04998.17 OIR55904.1 - 7.2e-21 74.8 0.1 7.9e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 AAL_decarboxy PF03306.13 OIR55904.1 - 0.13 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase zf-C3HC4_3 PF13920.6 OIR55905.1 - 1.5e-06 27.9 7.7 2.7e-06 27.2 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55905.1 - 0.00058 19.9 4.8 0.0012 19.0 4.8 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR55905.1 - 0.0088 16.4 7.7 0.015 15.6 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OIR55905.1 - 0.032 14.2 6.4 0.073 13.0 6.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OIR55905.1 - 0.076 12.9 4.9 0.19 11.6 4.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2024 PF09630.10 OIR55905.1 - 0.08 12.8 2.3 1.8 8.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) DZR PF12773.7 OIR55905.1 - 0.082 12.9 7.0 5.6 7.1 8.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon Sec16 PF12932.7 OIR55905.1 - 0.1 13.2 0.0 0.16 12.6 0.0 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region zf-RING_4 PF14570.6 OIR55905.1 - 0.47 10.3 11.3 1.7 8.5 3.3 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OIR55905.1 - 0.51 10.6 8.3 1.8 8.8 7.1 2.4 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 OIR55905.1 - 0.53 10.5 7.7 0.76 10.0 7.3 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger zf-Di19 PF05605.12 OIR55905.1 - 0.75 10.1 8.3 0.52 10.6 0.3 2.6 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Stc1 PF12898.7 OIR55905.1 - 2.3 8.8 8.3 1e+02 3.5 8.3 2.3 1 1 0 1 1 1 0 Stc1 domain HNH_5 PF14279.6 OIR55905.1 - 6 6.8 6.8 10 6.0 0.6 3.1 2 1 0 2 2 2 0 HNH endonuclease DUF4451 PF14616.6 OIR55905.1 - 9 6.5 9.2 8.3 6.6 3.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) rve PF00665.26 OIR55908.1 - 1.1e-22 80.4 0.0 1.6e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS1595 PF12762.7 OIR55908.1 - 0.0018 18.3 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain Integrase_H2C2 PF17921.1 OIR55908.1 - 0.01 15.9 1.0 0.021 14.9 1.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain rve_3 PF13683.6 OIR55908.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DDE_3 PF13358.6 OIR55908.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Tower PF09121.10 OIR55908.1 - 0.31 11.2 3.9 5 7.4 2.1 2.6 3 0 0 3 3 3 0 Tower BAF250_C PF12031.8 OIR55910.1 - 0.00021 20.7 0.0 0.095 12.0 0.0 2.1 1 1 1 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa zf-C3HC4_3 PF13920.6 OIR55913.1 - 0.00023 20.9 6.3 0.00023 20.9 6.3 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) RNase_H2-Ydr279 PF09468.10 OIR55913.1 - 0.067 13.4 0.4 0.084 13.1 0.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF4420 PF14390.6 OIR55913.1 - 0.1 11.8 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Putative PD-(D/E)XK family member, (DUF4420) RVT_1 PF00078.27 OIR55915.1 - 1.1e-33 116.6 0.0 1.4e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.21 OIR55919.1 - 4.7e-28 97.8 0.0 5.6e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OIR55919.1 - 2.3e-14 53.7 0.0 2.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OIR55919.1 - 1.8e-12 47.1 0.0 2.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OIR55919.1 - 9.5e-08 32.1 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OIR55919.1 - 1e-06 28.3 0.0 1.2e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OIR55919.1 - 2.2e-06 27.1 0.8 3.1e-05 23.3 0.2 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 OIR55919.1 - 4.2e-06 26.3 0.0 5.9e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 OIR55919.1 - 0.00075 19.4 0.0 0.00086 19.3 0.0 1.1 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.27 OIR55919.1 - 0.0075 16.8 0.0 0.01 16.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 OIR55919.1 - 0.009 16.1 0.0 1.4 9.0 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.6 OIR55919.1 - 0.012 15.9 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OIR55919.1 - 0.021 15.3 0.0 0.024 15.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OIR55919.1 - 0.026 15.1 0.0 0.03 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OIR55919.1 - 0.032 13.8 0.2 0.076 12.6 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 OIR55919.1 - 0.047 13.3 0.1 0.89 9.2 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 OIR55919.1 - 0.057 13.3 0.0 0.093 12.6 0.1 1.4 1 1 0 1 1 1 0 RsgA GTPase Thymidylate_kin PF02223.17 OIR55919.1 - 0.091 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase GTP_EFTU PF00009.27 OIR55919.1 - 0.099 12.2 0.0 6 6.4 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 OIR55919.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OIR55919.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 OIR55920.1 - 2.8e-08 33.6 4.1 4.8e-08 32.9 4.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 OIR55920.1 - 0.028 14.6 0.6 0.047 13.9 0.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF257 PF03192.13 OIR55920.1 - 0.063 13.1 0.9 0.082 12.7 0.9 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 WASH_WAHD PF11945.8 OIR55920.1 - 0.14 11.7 1.7 0.26 10.8 0.5 1.8 1 1 1 2 2 2 0 WAHD domain of WASH complex DUF1366 PF07104.11 OIR55920.1 - 0.18 11.5 1.5 7.5 6.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) Pkinase PF00069.25 OIR55921.1 - 5.6e-28 98.0 0.1 7.7e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55921.1 - 4.6e-15 55.6 0.0 5.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR55921.1 - 8.4e-07 28.5 0.3 1.4e-06 27.8 0.3 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR55921.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Phage_antitermQ PF06530.12 OIR55921.1 - 0.023 14.6 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Phage antitermination protein Q APH PF01636.23 OIR55921.1 - 0.048 13.6 0.1 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.6 OIR55922.1 - 4.9e-07 29.5 5.8 1e-06 28.5 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55922.1 - 0.00014 21.9 7.0 0.001 19.1 5.1 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OIR55922.1 - 0.033 14.0 4.3 0.15 11.9 4.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OIR55922.1 - 0.054 13.4 3.6 0.17 11.8 3.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Headcase PF16002.5 OIR55922.1 - 0.074 12.5 2.8 1.2 8.5 0.6 2.2 1 1 1 2 2 2 0 Headcase protein zf-C3HC4_4 PF15227.6 OIR55922.1 - 0.083 13.1 2.9 0.083 13.1 2.9 2.4 1 1 0 2 2 2 0 zinc finger of C3HC4-type, RING NOB1_Zn_bind PF08772.11 OIR55922.1 - 0.096 12.9 0.9 0.096 12.9 0.9 1.7 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_4 PF14570.6 OIR55922.1 - 0.22 11.3 11.8 0.18 11.6 8.2 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OIR55922.1 - 0.73 10.2 8.8 1.9 8.9 0.3 2.9 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2197 PF09963.9 OIR55922.1 - 0.78 10.1 8.2 1.4 9.3 6.3 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.7 OIR55922.1 - 0.79 9.8 7.1 6 7.0 7.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 OIR55922.1 - 1.7 8.7 5.9 16 5.6 0.0 3.0 2 1 0 2 2 2 0 BED zinc finger Auto_anti-p27 PF06677.12 OIR55922.1 - 2.1 8.6 7.5 5.9 7.1 2.1 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-CHY PF05495.12 OIR55922.1 - 2.5 8.6 9.0 30 5.2 9.0 2.4 1 1 0 1 1 1 0 CHY zinc finger RVT_1 PF00078.27 OIR55924.1 - 4.8e-17 62.2 0.0 7.4e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TIG PF01833.24 OIR55924.1 - 0.17 12.0 0.0 15 5.8 0.0 2.2 2 0 0 2 2 2 0 IPT/TIG domain Reg_prop PF07494.11 OIR55925.1 - 2.1e-11 42.6 5.1 0.53 10.7 0.1 6.0 6 0 0 6 6 6 5 Two component regulator propeller BAF250_C PF12031.8 OIR55925.1 - 2.3e-06 27.1 0.2 0.46 9.7 0.1 3.6 1 1 3 4 4 4 4 SWI/SNF-like complex subunit BAF250/Osa MlaD PF02470.20 OIR55925.1 - 0.011 16.0 0.1 43 4.5 0.0 4.8 4 2 2 6 6 6 0 MlaD protein Biotin_lipoyl PF00364.22 OIR55925.1 - 0.016 15.0 0.1 15 5.5 0.0 4.1 5 0 0 5 5 5 0 Biotin-requiring enzyme NikR_C PF08753.11 OIR55926.1 - 0.078 13.2 0.1 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain RVT_1 PF00078.27 OIR55930.1 - 1.8e-14 53.8 0.0 1.9e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sep15_SelM PF08806.11 OIR55931.1 - 8e-05 22.7 2.1 0.45 10.7 0.1 4.1 5 0 0 5 5 5 2 Sep15/SelM redox domain zf-SAP30 PF13866.6 OIR55931.1 - 0.013 15.6 0.2 2.9 8.1 0.0 4.1 5 1 1 6 6 6 0 SAP30 zinc-finger BAALC_N PF06989.12 OIR55931.1 - 0.12 12.7 0.3 8.9 6.7 0.1 2.6 2 0 0 2 2 2 0 BAALC N-terminus Reg_prop PF07494.11 OIR55931.1 - 0.71 10.3 7.4 3.5 8.2 0.1 4.7 5 0 0 5 5 5 0 Two component regulator propeller Exo_endo_phos_2 PF14529.6 OIR55932.1 - 0.011 15.6 0.0 0.08 12.8 0.0 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Sec3_C PF09763.9 OIR55934.1 - 0.068 11.6 0.1 0.099 11.0 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Sep15_SelM PF08806.11 OIR55935.1 - 0.00035 20.7 2.3 4.4 7.6 0.1 4.6 5 0 0 5 5 5 1 Sep15/SelM redox domain Reg_prop PF07494.11 OIR55935.1 - 0.00086 19.3 6.5 4.2 7.9 0.0 5.3 6 0 0 6 6 6 2 Two component regulator propeller DUF1561 PF07598.11 OIR55935.1 - 0.01 14.1 0.1 1.7 6.8 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1561) DUF2513 PF10711.9 OIR55935.1 - 0.056 13.7 0.1 6 7.2 0.0 2.4 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) TAT_ubiq PF07706.12 OIR55935.1 - 0.089 13.0 0.5 3.5 7.9 0.0 3.1 4 0 0 4 4 4 0 Aminotransferase ubiquitination site zf-SAP30 PF13866.6 OIR55935.1 - 0.13 12.4 0.1 2.3 8.4 0.1 3.1 2 1 1 3 3 3 0 SAP30 zinc-finger Msap1 PF17077.5 OIR55935.1 - 0.28 10.3 0.5 16 4.5 0.2 2.1 1 1 1 2 2 2 0 Mitotic spindle associated protein SHE1 Trypan_PARP PF05887.11 OIR55936.1 - 0.0086 16.1 9.6 0.013 15.5 9.6 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) OAD_gamma PF04277.13 OIR55936.1 - 0.47 11.1 2.7 0.91 10.2 2.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Integrase_DNA PF02920.15 OIR55938.1 - 0.022 14.4 1.5 0.039 13.7 1.5 1.4 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase PIN_12 PF16289.5 OIR55939.1 - 0.0021 18.6 0.2 0.0023 18.4 0.2 1.1 1 0 0 1 1 1 1 PIN domain TALPID3 PF15324.6 OIR55939.1 - 0.047 11.4 0.0 0.048 11.3 0.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Mig-14 PF07395.11 OIR55939.1 - 0.069 12.5 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Mig-14 Cob_adeno_trans PF01923.18 OIR55939.1 - 0.091 12.9 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Exo_endo_phos PF03372.23 OIR55943.1 - 0.093 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family NUC173 PF08161.12 OIR55945.1 - 0.031 13.9 0.0 0.044 13.4 0.0 1.4 1 1 0 1 1 1 0 NUC173 domain REPA_OB_2 PF16900.5 OIR55945.1 - 0.075 13.0 0.1 0.23 11.4 0.1 1.8 1 1 1 2 2 2 0 Replication protein A OB domain Raftlin PF15250.6 OIR55946.1 - 1.5 7.5 10.9 1.6 7.4 10.9 1.0 1 0 0 1 1 1 0 Raftlin DUF2981 PF11200.8 OIR55946.1 - 5.1 6.7 4.9 5.4 6.7 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CDC45 PF02724.14 OIR55947.1 - 0.45 8.7 6.0 0.48 8.7 6.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OIR55947.1 - 2.4 7.9 9.8 3.2 7.5 9.2 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 YacG PF03884.14 OIR55949.1 - 6.3e-06 25.8 0.0 5.6 6.8 0.0 5.8 7 0 0 7 7 7 2 DNA gyrase inhibitor YacG DUF2938 PF11158.8 OIR55949.1 - 0.01 15.3 0.6 5.4 6.5 0.0 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF2938) SpoIID PF08486.10 OIR55949.1 - 0.034 14.7 1.9 91 3.7 0.0 5.7 7 0 0 7 7 7 0 Stage II sporulation protein Ald_Xan_dh_C PF01315.22 OIR55949.1 - 0.055 13.8 1.9 1.4e+02 2.8 0.0 4.9 6 0 0 6 6 6 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MlaD PF02470.20 OIR55949.1 - 0.077 13.3 0.1 88 3.5 0.0 4.6 6 0 0 6 6 6 0 MlaD protein FANCI_HD2 PF14680.6 OIR55949.1 - 0.084 12.1 0.0 12 5.1 0.0 3.3 3 0 0 3 3 3 0 FANCI helical domain 2 SOR PF07682.11 OIR55949.1 - 0.099 11.5 1.2 16 4.2 0.0 3.9 1 1 5 6 6 6 0 Sulphur oxygenase reductase KR PF08659.10 OIR55949.1 - 2.5 8.0 6.7 35 4.2 0.0 4.0 3 1 2 5 5 5 0 KR domain Pkinase PF00069.25 OIR55951.1 - 6.8e-18 65.0 0.0 2.8e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55951.1 - 6.9e-11 41.9 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR55951.1 - 5.1e-05 22.4 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OIR55951.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RVT PF13966.6 OIR55952.1 - 0.0085 16.8 0.1 0.014 16.1 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase tRNA_int_endo PF01974.17 OIR55955.1 - 5.5e-09 36.0 0.0 8.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain TackOD1 PF18551.1 OIR55956.1 - 0.37 10.4 4.5 1.9 8.1 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF2746 PF10874.8 OIR55957.1 - 0.13 12.7 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) SMYLE_N PF18615.1 OIR55957.1 - 0.76 9.3 10.4 1 8.9 10.4 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Lin-8 PF03353.15 OIR55957.1 - 8.3 5.9 12.9 11 5.4 12.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FERM_M PF00373.18 OIR55959.1 - 0.12 12.8 0.1 0.15 12.5 0.1 1.1 1 0 0 1 1 1 0 FERM central domain Exo_endo_phos PF03372.23 OIR55961.1 - 0.013 15.1 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.23 OIR55962.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR55962.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase zf-C3HC4_3 PF13920.6 OIR55963.1 - 3.3e-05 23.6 7.4 6.3e-05 22.8 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR55963.1 - 0.0025 17.9 5.5 0.0025 17.9 5.5 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR55963.1 - 0.0089 16.2 6.2 0.0089 16.2 6.2 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR55963.1 - 0.036 13.8 7.7 0.48 10.2 7.8 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR55963.1 - 0.13 12.2 6.8 0.26 11.3 6.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Stc1 PF12898.7 OIR55963.1 - 0.22 12.1 3.6 1.3 9.7 0.8 2.4 2 0 0 2 2 2 0 Stc1 domain zf-Di19 PF05605.12 OIR55963.1 - 0.52 10.6 8.1 0.44 10.9 2.5 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 OIR55963.1 - 0.62 10.1 5.2 13 5.9 6.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF4451 PF14616.6 OIR55963.1 - 1.4 9.2 5.2 0.72 10.1 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) DUF2197 PF09963.9 OIR55963.1 - 2.8 8.3 7.3 2.7 8.3 4.6 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-RING_UBOX PF13445.6 OIR55963.1 - 3.5 7.7 5.2 8.4 6.5 5.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Tox-ODYAM1 PF15642.6 OIR55964.1 - 0.02 13.9 3.3 0.022 13.7 3.3 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus RNA_pol_Rpb2_2 PF04561.14 OIR55964.1 - 0.024 14.3 1.4 0.028 14.1 1.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 DUF3929 PF13066.6 OIR55964.1 - 0.062 13.4 2.4 0.085 12.9 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3929) zf-RVT PF13966.6 OIR55966.1 - 0.0053 17.4 0.1 0.0096 16.6 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase QSOX_Trx1 PF18108.1 OIR55969.1 - 0.1 12.8 1.8 0.89 9.8 0.2 2.0 1 1 1 2 2 2 0 QSOX Trx-like domain FHA_2 PF17913.1 OIR55970.1 - 5.4e-05 23.3 0.1 7.1 6.9 0.0 3.9 4 0 0 4 4 4 3 FHA domain RHH_4 PF13467.6 OIR55970.1 - 0.051 13.5 0.1 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain Pkinase PF00069.25 OIR55971.1 - 2.3e-12 46.8 0.1 2.7e-12 46.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55971.1 - 7.6e-06 25.4 0.1 8.8e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OIR55971.1 - 0.071 12.7 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 tRNA_bind_2 PF13725.6 OIR55972.1 - 1.2e-17 64.4 0.0 1.3e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Possible tRNA binding domain DprA_WH PF17782.1 OIR55972.1 - 0.012 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 DprA winged helix domain RVT_1 PF00078.27 OIR55973.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ISG65-75 PF11727.8 OIR55974.1 - 0.019 14.2 2.2 0.023 14.0 2.2 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein NPM1-C PF16276.5 OIR55974.1 - 0.079 12.9 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain ATC_hydrolase PF14196.6 OIR55974.1 - 0.12 13.1 1.3 0.15 12.8 1.3 1.3 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase DUF4407 PF14362.6 OIR55974.1 - 0.2 11.0 6.0 0.2 11.0 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Porin_5 PF16930.5 OIR55974.1 - 0.31 9.5 5.2 0.36 9.3 5.2 1.1 1 0 0 1 1 1 0 Putative porin zf-RING_14 PF17978.1 OIR55976.1 - 0.056 13.9 1.0 0.1 13.0 1.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1487 PF07368.11 OIR55979.1 - 0.0011 18.5 0.3 0.073 12.5 0.1 3.0 1 1 1 3 3 3 1 Protein of unknown function (DUF1487) NikR_C PF08753.11 OIR55979.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 NikR C terminal nickel binding domain BAF250_C PF12031.8 OIR55979.1 - 0.06 12.6 0.0 0.21 10.8 0.0 1.9 1 1 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Proteasome PF00227.26 OIR55980.1 - 2.1e-29 102.4 0.1 2.6e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR55980.1 - 2.1e-14 52.9 0.0 4.8e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CCDC53 PF10152.9 OIR55981.1 - 0.037 14.4 2.1 0.077 13.4 2.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2457 PF10446.9 OIR55981.1 - 0.21 10.7 6.2 0.28 10.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Reg_prop PF07494.11 OIR55982.1 - 3.6e-07 29.6 0.4 14 6.3 0.0 6.3 6 0 0 6 6 6 1 Two component regulator propeller TnpV PF14198.6 OIR55982.1 - 0.00092 19.2 15.3 3.6 7.6 0.2 6.6 5 1 0 6 6 6 2 Transposon-encoded protein TnpV DUF3860 PF12976.7 OIR55982.1 - 0.022 14.8 1.9 1.3e+02 2.7 0.0 5.4 5 1 1 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3860) Choline_kin_N PF04428.14 OIR55982.1 - 0.049 13.3 0.0 1.3 8.7 0.0 3.3 3 0 0 3 3 3 0 Choline kinase N terminus Terminase_5 PF06056.12 OIR55982.1 - 0.085 12.8 1.6 9.3 6.2 0.0 3.9 5 0 0 5 5 5 0 Putative ATPase subunit of terminase (gpP-like) Nuc_sug_transp PF04142.15 OIR55982.1 - 0.24 10.6 15.4 15 4.7 0.0 5.7 4 2 2 6 6 6 0 Nucleotide-sugar transporter Nucleic_acid_bd PF13820.6 OIR55982.1 - 0.27 11.1 8.4 64 3.4 0.0 5.3 5 1 1 6 6 6 0 Putative nucleic acid-binding region DUF1213 PF06740.12 OIR55982.1 - 0.28 11.8 0.3 48 4.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) Sep15_SelM PF08806.11 OIR55982.1 - 1.1 9.4 15.4 6.7 6.9 0.1 5.1 6 0 0 6 6 6 0 Sep15/SelM redox domain DUF1125 PF06563.11 OIR55982.1 - 6.3 6.8 9.8 36 4.4 0.0 5.0 6 0 0 6 6 6 0 Protein of unknown function (DUF1125) Imm58 PF15581.6 OIR55982.1 - 9.3 6.4 8.0 14 5.9 0.0 4.1 5 1 0 5 5 5 0 Immunity protein 58 Reovirus_M2 PF05993.12 OIR55983.1 - 0.22 9.6 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Baculo_LEF-11 PF06385.12 OIR55984.1 - 0.029 14.9 3.2 0.093 13.2 0.3 2.2 2 0 0 2 2 2 0 Baculovirus LEF-11 protein zf-RVT PF13966.6 OIR55985.1 - 0.0083 16.8 0.1 0.015 16.0 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Vta1_C PF18097.1 OIR55985.1 - 0.17 11.6 0.2 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Vta1 C-terminal domain PHtD_u1 PF16645.5 OIR55985.1 - 0.19 12.2 0.5 1.1 9.8 0.1 2.1 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein CENP-F_leu_zip PF10473.9 OIR55988.1 - 0.0029 17.6 12.2 0.0047 17.0 12.2 1.3 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ALIX_LYPXL_bnd PF13949.6 OIR55988.1 - 0.064 12.5 10.1 0.09 12.1 10.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV ERM PF00769.19 OIR55988.1 - 0.12 12.1 20.5 0.17 11.7 20.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HC2 PF07382.11 OIR55988.1 - 0.16 12.0 19.2 0.25 11.4 19.2 1.3 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF5398 PF17376.2 OIR55988.1 - 0.21 12.2 1.6 0.48 11.1 1.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5398) PEARLI-4 PF05278.12 OIR55988.1 - 0.44 10.1 8.8 0.34 10.5 7.3 1.4 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) GAS PF13851.6 OIR55988.1 - 1 8.7 15.9 1.5 8.1 15.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MAD PF05557.13 OIR55988.1 - 2.3 6.5 16.1 3 6.1 16.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 OIR55988.1 - 6.3 5.6 16.7 8.7 5.1 16.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TP53IP5 PF15331.6 OIR55988.1 - 8.3 6.5 8.1 12 5.9 8.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-C3HC4_3 PF13920.6 OIR55993.1 - 0.025 14.4 4.0 0.3 11.0 4.1 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OIR55993.1 - 0.035 14.1 0.5 0.071 13.2 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 OIR55993.1 - 0.12 12.7 2.3 0.18 12.2 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.6 OIR55993.1 - 0.21 11.9 1.3 0.63 10.4 1.3 1.9 1 0 0 1 1 1 0 Ring finger domain rve PF00665.26 OIR55994.1 - 2.1e-18 66.6 0.1 3.6e-18 65.9 0.0 1.4 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OIR55994.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Pkinase PF00069.25 OIR55995.1 - 1.1e-36 126.6 0.1 1.5e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR55995.1 - 6.3e-19 68.3 0.0 9.1e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR55995.1 - 0.0003 19.8 0.1 0.00044 19.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OIR55995.1 - 0.00083 18.8 0.2 0.0017 17.7 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR55995.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OIR55995.1 - 0.11 12.1 0.5 0.16 11.5 0.1 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF1487 PF07368.11 OIR55996.1 - 0.0035 16.8 0.0 21 4.5 0.0 3.7 1 1 3 4 4 4 3 Protein of unknown function (DUF1487) YacG PF03884.14 OIR55996.1 - 0.0056 16.4 0.0 14 5.5 0.0 3.7 4 0 0 4 4 4 2 DNA gyrase inhibitor YacG Sh_2 PF17512.2 OIR55996.1 - 0.03 14.1 0.3 7.7 6.3 0.0 2.8 1 1 1 3 3 3 0 Metapneumovirus Small hydrophobic protein DUF3929 PF13066.6 OIR55997.1 - 0.0058 16.7 0.5 0.01 15.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3929) CdiI_N PF18228.1 OIR55999.1 - 0.019 14.8 0.2 0.027 14.3 0.2 1.1 1 0 0 1 1 1 0 CdiI N-terminal domain KdpD PF02702.17 OIR55999.1 - 0.051 13.0 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain O-antigen_lig PF13425.6 OIR55999.1 - 0.09 11.6 0.3 0.11 11.3 0.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein YacG PF03884.14 OIR56000.1 - 2.1e-05 24.2 0.0 2 8.2 0.0 4.7 5 0 0 5 5 5 1 DNA gyrase inhibitor YacG MlaD PF02470.20 OIR56000.1 - 0.021 15.1 0.0 87 3.5 0.0 3.9 4 0 0 4 4 4 0 MlaD protein SpoIID PF08486.10 OIR56000.1 - 0.033 14.7 0.3 11 6.7 0.0 3.6 4 0 0 4 4 4 0 Stage II sporulation protein TTRAP PF14203.6 OIR56000.1 - 0.093 12.7 0.1 24 5.0 0.0 3.1 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein RE_EcoO109I PF14511.6 OIR56000.1 - 0.12 12.0 0.0 1.7 8.2 0.0 2.2 1 1 1 2 2 2 0 Type II restriction endonuclease EcoO109I RXLR PF16810.5 OIR56002.1 - 0.14 12.6 1.0 0.17 12.3 1.0 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity zf-C3HC4_3 PF13920.6 OIR56003.1 - 5e-06 26.3 7.7 1.2e-05 25.1 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56003.1 - 0.00067 19.7 5.5 0.0018 18.3 5.5 1.7 1 0 0 1 1 1 1 Zinc-binding RING-finger Thioredoxin_3 PF13192.6 OIR56003.1 - 0.023 14.7 0.8 1.1 9.4 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin domain TnpV PF14198.6 OIR56003.1 - 0.034 14.1 3.6 0.12 12.4 0.3 3.2 3 1 1 4 4 4 0 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR56003.1 - 0.096 13.0 0.1 48 4.7 0.0 3.5 3 0 0 3 3 3 0 Two component regulator propeller zf-Di19 PF05605.12 OIR56003.1 - 0.2 11.9 7.3 2.1 8.7 0.4 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE_2 PF02318.16 OIR56003.1 - 0.41 10.9 12.9 2.1 8.6 8.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 OIR56003.1 - 0.74 10.0 7.1 0.29 11.3 3.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OIR56003.1 - 0.93 9.5 11.6 0.76 9.8 9.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 OIR56003.1 - 1 9.5 9.5 6.1 7.0 7.5 2.5 2 1 1 3 3 2 0 Double zinc ribbon FGAR-AT_linker PF18072.1 OIR56003.1 - 1.2 9.7 3.9 3.6 8.2 0.1 3.2 4 0 0 4 4 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain zf-RING_4 PF14570.6 OIR56003.1 - 2 8.3 14.2 11 5.9 10.5 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OIR56003.1 - 3.1 7.9 8.7 3 8.0 5.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OIR56003.1 - 3.6 7.5 12.6 5.7 6.9 9.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OIR56006.1 - 7.4e-06 25.6 2.0 3.9 8.0 0.1 4.9 5 0 0 5 5 5 4 Two component regulator propeller RVT_1 PF00078.27 OIR56007.1 - 3.5e-39 134.6 0.0 4.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OIR56010.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OIR56010.1 - 0.0019 18.4 0.1 0.0032 17.6 0.1 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_Zn PF02022.19 OIR56010.1 - 0.018 15.0 0.6 0.031 14.2 0.6 1.5 1 1 0 1 1 1 0 Integrase Zinc binding domain SWIRM-assoc_1 PF16495.5 OIR56011.1 - 0.05 13.6 2.3 0.13 12.3 1.1 2.3 1 1 0 2 2 2 0 SWIRM-associated region 1 PHM7_ext PF12621.8 OIR56012.1 - 0.00059 20.0 0.5 14 6.0 0.0 4.7 5 1 0 5 5 5 1 Extracellular tail, of 10TM putative phosphate transporter EXOSC1 PF10447.9 OIR56012.1 - 0.0019 18.8 1.6 21 5.7 0.0 4.3 2 1 4 6 6 6 1 Exosome component EXOSC1/CSL4 DUF4825 PF16107.5 OIR56012.1 - 0.0037 17.4 3.9 11 6.2 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4825) Reg_prop PF07494.11 OIR56012.1 - 0.0041 17.2 0.2 89 3.9 0.0 4.8 5 0 0 5 5 5 0 Two component regulator propeller MqsR_toxin PF15723.5 OIR56012.1 - 0.089 13.2 0.4 13 6.2 0.0 3.6 3 1 1 4 4 4 0 Motility quorum-sensing regulator, toxin of MqsA DUF1323 PF07037.11 OIR56012.1 - 0.24 11.8 6.3 3.6 8.0 0.1 3.2 2 1 2 4 4 4 0 Putative transcription regulator (DUF1323) Lectin_C PF00059.21 OIR56012.1 - 0.68 10.7 2.0 55 4.5 0.0 3.5 4 0 0 4 4 4 0 Lectin C-type domain Baculo_LEF-11 PF06385.12 OIR56012.1 - 2 9.0 10.0 12 6.5 0.5 4.3 2 2 1 4 4 4 0 Baculovirus LEF-11 protein Haem_oxygenas_2 PF14518.6 OIR56013.1 - 0.045 13.5 0.1 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Iron-containing redox enzyme zf-C3HC4_3 PF13920.6 OIR56014.1 - 0.0027 17.5 7.0 0.0047 16.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56014.1 - 0.017 15.2 3.1 0.039 14.1 3.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR56014.1 - 0.057 13.8 7.5 0.11 12.8 7.5 1.5 1 0 0 1 1 1 0 Ring finger domain zinc_ribbon_9 PF14369.6 OIR56014.1 - 0.22 11.8 2.5 8.6 6.7 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-C3HC4_4 PF15227.6 OIR56014.1 - 0.29 11.3 6.3 0.078 13.2 2.6 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 OIR56014.1 - 0.37 11.0 3.7 0.87 9.8 3.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 OIR56014.1 - 2.1 8.3 7.0 5.6 6.9 7.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 OIR56014.1 - 4.8 7.3 5.8 1.2e+02 2.9 6.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 OIR56017.1 - 0.00061 19.6 4.4 0.001 18.9 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56017.1 - 0.017 15.2 3.4 0.03 14.4 3.4 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_Tnp_IS1595 PF12760.7 OIR56017.1 - 0.065 13.2 0.3 0.065 13.2 0.3 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-Di19 PF05605.12 OIR56017.1 - 0.11 12.8 0.5 0.19 12.0 0.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 OIR56017.1 - 0.14 12.2 0.7 0.24 11.5 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_2 PF13639.6 OIR56017.1 - 0.17 12.2 3.7 0.28 11.5 3.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OIR56017.1 - 0.2 11.6 3.2 0.33 10.9 3.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 OIR56017.1 - 0.26 11.1 4.8 0.49 10.2 4.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OIR56017.1 - 0.36 10.7 1.7 0.66 9.9 1.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HC2 PF07382.11 OIR56018.1 - 0.0061 16.7 20.7 0.0061 16.7 20.7 1.5 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 DUF5398 PF17376.2 OIR56018.1 - 0.76 10.4 4.1 0.26 11.9 0.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5398) DUF5387 PF17361.2 OIR56018.1 - 1.3 8.7 14.5 1.6 8.3 14.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5387) PhoD_N PF16655.5 OIR56018.1 - 3.1 8.4 5.1 26 5.5 5.0 2.3 1 1 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Macoilin PF09726.9 OIR56018.1 - 3.6 6.0 12.5 4.1 5.8 12.5 1.1 1 0 0 1 1 1 0 Macoilin family Asp-B-Hydro_N PF05279.11 OIR56018.1 - 4.6 7.2 32.3 6.8 6.7 32.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vps53_N PF04100.12 OIR56018.1 - 7.7 5.4 10.9 3.8 6.4 3.8 2.0 1 1 1 2 2 2 0 Vps53-like, N-terminal FUSC PF04632.12 OIR56018.1 - 8.2 4.8 16.3 11 4.4 16.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LAP1C PF05609.12 OIR56018.1 - 9.1 5.2 17.5 11 5.0 17.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Phage_holin_7_1 PF16081.5 OIR56018.1 - 9.9 6.4 18.1 3.9 7.6 14.3 2.0 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family EXOSC1 PF10447.9 OIR56019.1 - 4.7e-05 24.0 0.6 2.4 8.8 0.1 4.7 2 1 4 6 6 6 2 Exosome component EXOSC1/CSL4 Thioredoxin PF00085.20 OIR56019.1 - 0.0013 18.7 0.1 8.6 6.4 0.0 4.7 6 0 0 6 6 6 1 Thioredoxin DUF2986 PF11661.8 OIR56019.1 - 0.78 10.3 2.6 24 5.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2986) Cas_Cas4 PF01930.17 OIR56019.1 - 1.5 8.9 14.3 15 5.6 0.3 5.1 1 1 5 6 6 6 0 Domain of unknown function DUF83 zf-C3HC4_3 PF13920.6 OIR56020.1 - 8.5e-06 25.5 9.0 2.1e-05 24.3 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM35_C PF15793.5 OIR56020.1 - 0.00021 20.7 1.8 0.00031 20.2 1.8 1.2 1 0 0 1 1 1 1 Protein family FAM35, C-terminal Prok-RING_4 PF14447.6 OIR56020.1 - 0.00037 20.3 10.6 0.0013 18.5 7.0 2.9 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OIR56020.1 - 0.00038 20.7 9.1 0.00038 20.7 9.1 2.4 2 0 0 2 2 2 1 Ring finger domain FYVE_2 PF02318.16 OIR56020.1 - 0.0013 18.9 6.2 0.0032 17.7 6.2 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR56020.1 - 0.24 11.2 11.4 0.21 11.4 8.1 2.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OIR56020.1 - 0.53 10.4 4.8 0.22 11.6 1.4 2.2 2 1 0 2 2 2 0 RING-type zinc-finger DZR PF12773.7 OIR56020.1 - 0.97 9.5 6.1 6.6 6.9 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.6 OIR56020.1 - 3 7.9 9.1 4.3 7.4 7.6 2.2 2 1 0 2 2 2 0 zinc-RING finger domain Reg_prop PF07494.11 OIR56021.1 - 0.039 14.2 0.0 3.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Two component regulator propeller DUF4247 PF14042.6 OIR56022.1 - 0.096 13.4 0.1 6.1 7.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4247) RVT_1 PF00078.27 OIR56024.1 - 0.0098 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1654 PF07867.11 OIR56024.1 - 0.033 13.9 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) RVT_1 PF00078.27 OIR56025.1 - 2.1e-21 76.5 0.0 2.5e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3823 PF12866.7 OIR56025.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain RVT_1 PF00078.27 OIR56026.1 - 3.1e-39 134.8 0.0 4.3e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb4 PF03874.16 OIR56027.1 - 0.15 12.4 1.1 0.28 11.5 0.2 2.0 2 1 0 2 2 2 0 RNA polymerase Rpb4 UBZ_FAAP20 PF15750.5 OIR56028.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger Exo_endo_phos PF03372.23 OIR56030.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ANAPC15 PF15243.6 OIR56032.1 - 0.0018 18.6 0.2 7.9 7.0 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 15 NBD94 PF16830.5 OIR56032.1 - 0.1 13.0 0.1 15 6.1 0.0 3.7 4 0 0 4 4 4 0 Nucleotide-Binding Domain 94 of RH gag-asp_proteas PF13975.6 OIR56033.1 - 6.3e-11 42.7 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56033.1 - 1.2e-10 41.9 0.0 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OIR56033.1 - 8.8e-09 35.2 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OIR56033.1 - 4e-08 33.4 0.0 7.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OIR56033.1 - 8.1e-07 28.8 2.2 1.9e-06 27.6 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease PF09668.10 OIR56033.1 - 0.00059 19.6 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_6 PF15288.6 OIR56033.1 - 0.0012 18.7 1.4 0.0023 17.7 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OIR56033.1 - 0.037 13.8 0.8 0.1 12.4 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF1758 PF05585.12 OIR56033.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-CCHC_2 PF13696.6 OIR56033.1 - 0.24 11.3 0.8 0.47 10.3 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle BsuBI_PstI_RE PF06616.11 OIR56034.1 - 0.024 13.9 0.1 0.042 13.1 0.1 1.5 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain CybS PF05328.12 OIR56034.1 - 0.031 14.0 0.7 0.8 9.4 0.2 2.2 1 1 1 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit Topo_Zn_Ribbon PF08272.11 OIR56034.1 - 0.043 13.5 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like rve PF00665.26 OIR56035.1 - 1.1e-12 48.1 0.2 3.8e-12 46.4 0.0 1.9 2 1 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OIR56035.1 - 0.0057 16.4 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 OIR56036.1 - 0.0042 17.8 0.1 0.0063 17.2 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-CCHC PF00098.23 OIR56037.1 - 8.4e-06 25.6 2.6 8.4e-06 25.6 2.6 1.7 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 OIR56037.1 - 6.8e-05 23.1 0.0 9.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 OIR56037.1 - 0.021 14.6 1.7 0.047 13.4 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Reg_prop PF07494.11 OIR56038.1 - 0.0073 16.4 0.0 51 4.6 0.0 3.9 3 0 0 3 3 3 0 Two component regulator propeller ANAPC15 PF15243.6 OIR56038.1 - 0.029 14.7 1.6 35 4.9 0.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 BAF250_C PF12031.8 OIR56038.1 - 0.084 12.2 0.0 6.2 6.0 0.0 2.3 1 1 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa BET PF17035.5 OIR56038.1 - 0.36 11.0 2.4 6.1 7.1 0.1 3.6 5 0 0 5 5 5 0 Bromodomain extra-terminal - transcription regulation BAF250_C PF12031.8 OIR56039.1 - 0.0066 15.8 0.1 5 6.3 0.0 2.7 1 1 0 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa ANAPC15 PF15243.6 OIR56039.1 - 0.0081 16.5 4.0 17 5.9 0.1 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 15 Reg_prop PF07494.11 OIR56039.1 - 0.02 15.0 0.0 1e+02 3.7 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller DUF2247 PF10004.9 OIR56039.1 - 0.037 13.8 3.0 0.16 11.7 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2247) Nuc_sug_transp PF04142.15 OIR56039.1 - 0.19 10.8 0.1 50 2.9 0.0 3.0 3 0 0 3 3 3 0 Nucleotide-sugar transporter TnpV PF14198.6 OIR56039.1 - 0.35 10.9 5.3 13 5.8 0.0 3.8 5 0 0 5 5 5 0 Transposon-encoded protein TnpV BET PF17035.5 OIR56039.1 - 0.42 10.8 5.8 6.1 7.1 0.1 4.3 5 0 0 5 5 5 0 Bromodomain extra-terminal - transcription regulation Pkinase PF00069.25 OIR56041.1 - 6e-26 91.4 0.2 6.1e-25 88.1 0.3 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56041.1 - 2.7e-16 59.6 0.1 3.7e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR56041.1 - 2.7e-06 26.6 0.1 3.5e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OIR56041.1 - 0.00058 19.3 0.1 0.00089 18.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR56041.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OIR56041.1 - 0.079 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OIR56041.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family RVT_1 PF00078.27 OIR56044.1 - 5.9e-11 42.3 0.0 1.6e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) GalKase_gal_bdg PF10509.9 OIR56045.1 - 0.15 11.7 0.2 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Galactokinase galactose-binding signature DUF5437 PF17505.2 OIR56045.1 - 0.48 10.5 1.5 0.72 9.9 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5437) Pkinase PF00069.25 OIR56048.1 - 2.2e-28 99.3 0.0 5.7e-28 98.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56048.1 - 2.2e-16 60.0 0.0 2.9e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56048.1 - 1.6e-06 27.6 0.1 2.7e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR56048.1 - 0.018 14.6 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OIR56048.1 - 0.022 13.7 0.1 0.025 13.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 OIR56048.1 - 0.034 13.7 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OIR56048.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OIR56049.1 - 2.3e-32 112.4 1.5 1.2e-31 110.1 0.6 1.9 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56049.1 - 4.4e-20 72.1 0.1 6.1e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR56049.1 - 0.0031 16.5 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56049.1 - 0.0049 16.8 0.1 0.1 12.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR56049.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56049.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family tRNA-synt_2c PF01411.19 OIR56050.1 - 3.1e-62 210.8 0.0 3.5e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) zf-RVT PF13966.6 OIR56053.1 - 0.015 16.0 2.3 0.026 15.3 1.7 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56053.1 - 0.027 14.5 2.4 0.073 13.1 2.4 1.6 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain gag-asp_proteas PF13975.6 OIR56054.1 - 9.8e-10 38.9 0.1 2.1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56054.1 - 1.3e-08 35.3 0.2 3.4e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OIR56054.1 - 0.00099 19.4 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-C2H2_10 PF16588.5 OIR56054.1 - 0.01 15.5 3.8 0.018 14.8 3.8 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger RVP_2 PF08284.11 OIR56054.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 OIR56055.1 - 3.1e-34 118.4 0.0 4.7e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OIR56055.1 - 4.4e-24 84.4 0.0 1.4e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OIR56055.1 - 1.9e-14 53.8 0.0 6.2e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase DUF2250 PF10007.9 OIR56055.1 - 0.043 13.9 0.1 13 6.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) HTH_Crp_2 PF13545.6 OIR56055.1 - 0.05 13.6 0.1 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain TxDE PF18711.1 OIR56055.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Toxoflavin-degrading enzyme rve PF00665.26 OIR56056.1 - 1.4e-24 86.6 0.0 2.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OIR56056.1 - 2.3e-08 34.3 0.6 5.5e-08 33.1 0.6 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OIR56056.1 - 2.7e-05 24.2 0.2 6.1e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OIR56056.1 - 9.5e-05 22.1 0.0 0.00026 20.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 OIR56056.1 - 0.0015 18.3 0.1 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_IS240 PF13610.6 OIR56056.1 - 0.003 17.8 0.2 0.013 15.7 0.1 2.0 2 0 0 2 2 2 1 DDE domain Tex_N PF09371.10 OIR56056.1 - 0.006 16.3 0.1 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 Tex-like protein N-terminal domain Pkinase PF00069.25 OIR56058.1 - 4e-38 131.3 0.0 2.5e-37 128.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56058.1 - 5.3e-24 84.9 0.0 7.5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OIR56058.1 - 1.4e-07 30.6 0.0 3.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OIR56058.1 - 0.0032 16.8 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like zf-dskA_traR PF01258.17 OIR56058.1 - 0.17 11.9 0.1 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger XRN_M PF17846.1 OIR56059.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Xrn1 helical domain CENP-C_mid PF15620.6 OIR56060.1 - 0.031 14.2 0.0 0.12 12.4 0.0 2.0 2 1 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region DnaB_C PF03796.15 OIR56062.1 - 0.075 12.4 0.2 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF1831 PF08866.10 OIR56062.1 - 0.39 11.2 4.1 0.78 10.2 4.1 1.5 1 0 0 1 1 1 0 Putative amino acid metabolism RNA_pol_Rpb4 PF03874.16 OIR56063.1 - 0.013 15.9 1.0 0.035 14.4 1.0 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb4 CooT PF10133.9 OIR56063.1 - 0.032 14.5 0.1 11 6.4 0.1 2.8 3 0 0 3 3 3 0 CO dehydrogenase accessory protein CooT DUF4570 PF15134.6 OIR56064.1 - 0.027 14.5 0.2 0.035 14.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) YacG PF03884.14 OIR56067.1 - 0.00016 21.3 0.0 3.7 7.3 0.0 5.2 6 0 0 6 6 6 1 DNA gyrase inhibitor YacG SpoIID PF08486.10 OIR56067.1 - 0.062 13.9 0.7 71 4.1 0.0 4.2 5 0 0 5 5 5 0 Stage II sporulation protein zf-C3HC4_3 PF13920.6 OIR56068.1 - 0.00014 21.6 3.2 0.00026 20.8 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DnaJ_CXXCXGXG PF00684.19 OIR56068.1 - 0.068 13.5 0.8 0.068 13.5 0.8 2.0 3 0 0 3 3 3 0 DnaJ central domain zf-RING_4 PF14570.6 OIR56068.1 - 0.11 12.3 4.7 0.32 10.8 4.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 OIR56068.1 - 0.25 11.2 4.1 0.81 9.6 4.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OIR56068.1 - 0.28 11.4 8.3 0.056 13.7 3.8 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.29 OIR56068.1 - 0.42 10.5 4.7 0.88 9.5 4.7 1.6 1 0 0 1 1 1 0 PHD-finger TF_Zn_Ribbon PF08271.12 OIR56068.1 - 0.75 9.4 6.0 0.45 10.1 3.5 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zf-C3HC4_4 PF15227.6 OIR56068.1 - 0.78 10.0 5.9 0.61 10.3 3.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OIR56068.1 - 1.4 9.0 4.5 4 7.5 4.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.25 OIR56069.1 - 3.8e-33 115.0 0.0 7.4e-33 114.0 0.2 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56069.1 - 1.3e-20 73.8 0.1 1.8e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56069.1 - 6.4e-06 25.7 0.1 9.6e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56069.1 - 2.1e-05 23.7 0.1 3.4e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OIR56069.1 - 0.00081 19.1 0.2 0.016 14.9 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OIR56069.1 - 0.049 13.6 0.0 3.9 7.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OIR56069.1 - 0.1 12.2 0.1 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Exo_endo_phos PF03372.23 OIR56071.1 - 5.8e-07 29.3 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2624 PF11116.8 OIR56072.1 - 0.0078 17.1 0.5 0.017 16.0 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2624) BsuBI_PstI_RE PF06616.11 OIR56072.1 - 0.014 14.7 0.3 0.021 14.1 0.3 1.5 1 1 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain Tox-ODYAM1 PF15642.6 OIR56073.1 - 0.02 13.9 3.3 0.022 13.7 3.3 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus RNA_pol_Rpb2_2 PF04561.14 OIR56073.1 - 0.024 14.3 1.4 0.028 14.1 1.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 DUF3929 PF13066.6 OIR56073.1 - 0.062 13.4 2.4 0.085 12.9 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3929) Pkinase PF00069.25 OIR56074.1 - 3.6e-26 92.1 0.1 4.5e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56074.1 - 1.3e-14 54.1 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56074.1 - 2.7e-08 33.4 0.1 4.2e-08 32.8 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR56074.1 - 0.0056 16.3 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Methyltransf_12 PF08242.12 OIR56074.1 - 0.063 14.0 0.0 0.11 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Choline_kinase PF01633.20 OIR56074.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OIR56074.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Sep15_SelM PF08806.11 OIR56075.1 - 0.00027 21.0 0.2 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 Sep15/SelM redox domain Sep15_SelM PF08806.11 OIR56076.1 - 0.13 12.5 0.2 0.52 10.5 0.1 1.8 1 1 1 2 2 2 0 Sep15/SelM redox domain Pkinase PF00069.25 OIR56077.1 - 5.2e-32 111.2 0.1 5.9e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56077.1 - 3.7e-19 69.0 0.0 5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56077.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56077.1 - 0.0026 17.4 0.6 0.0073 15.9 0.6 1.7 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OIR56077.1 - 0.0096 14.9 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56077.1 - 0.053 13.4 0.2 2.4 8.0 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-RVT PF13966.6 OIR56078.1 - 0.00029 21.5 0.1 0.00046 20.8 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MlaD PF02470.20 OIR56079.1 - 0.12 12.7 0.0 1 9.7 0.0 2.0 1 1 1 2 2 2 0 MlaD protein gag-asp_proteas PF13975.6 OIR56082.1 - 3.5e-08 33.9 0.1 7.3e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 OIR56082.1 - 1.8e-05 24.6 0.4 2.8e-05 24.0 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 OIR56082.1 - 4.6e-05 23.7 0.1 0.00096 19.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OIR56082.1 - 0.0001 22.8 0.1 0.00025 21.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease Toxin_TOLIP PF00087.21 OIR56082.1 - 0.26 11.6 2.0 0.58 10.4 2.0 1.5 1 0 0 1 1 1 0 Snake toxin and toxin-like protein Reg_prop PF07494.11 OIR56085.1 - 8.4e-05 22.3 1.5 21 5.8 0.0 5.8 6 0 0 6 6 6 1 Two component regulator propeller DUF2714 PF10896.8 OIR56085.1 - 0.01 15.9 2.6 1.7 8.7 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2714) DUF4380 PF14315.6 OIR56085.1 - 0.031 13.2 0.3 3.5 6.5 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4380) ANAPC15 PF15243.6 OIR56085.1 - 0.049 14.0 4.8 6.8 7.2 0.0 4.7 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 15 ADAM_spacer1 PF05986.14 OIR56085.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Pim PF16765.5 OIR56085.1 - 0.6 10.3 4.9 29 4.9 0.1 4.7 6 0 0 6 6 6 0 Pesticin immunity protein FHA_2 PF17913.1 OIR56087.1 - 0.0061 16.8 0.3 18 5.7 0.0 4.0 3 1 1 4 4 4 1 FHA domain Mannitol_dh_C PF08125.13 OIR56087.1 - 0.063 12.7 1.3 50 3.2 0.0 4.1 4 1 0 4 4 4 0 Mannitol dehydrogenase C-terminal domain SPATA6 PF14909.6 OIR56087.1 - 0.094 12.9 0.4 13 5.9 0.0 3.7 4 1 1 5 5 5 0 Spermatogenesis-assoc protein 6 EABR PF12180.8 OIR56087.1 - 0.098 12.3 0.1 28 4.4 0.0 3.9 4 0 0 4 4 4 0 TSG101 and ALIX binding domain of CEP55 HIF-1a_CTAD PF08778.10 OIR56087.1 - 2.2 8.0 5.7 0.2 11.3 0.3 2.2 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain CENP-M PF11111.8 OIR56088.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) DUF3060 PF11259.8 OIR56089.1 - 0.0076 15.9 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3060) MlaD PF02470.20 OIR56089.1 - 0.11 12.8 0.0 7.3 7.0 0.0 2.1 2 0 0 2 2 2 0 MlaD protein zf-C3HC4_3 PF13920.6 OIR56090.1 - 4.9e-06 26.3 7.2 8e-06 25.6 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR56090.1 - 0.0052 17.1 7.7 0.0087 16.4 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OIR56090.1 - 0.013 15.4 6.0 0.02 14.9 5.3 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-Di19 PF05605.12 OIR56090.1 - 0.056 13.7 9.5 0.2 12.0 0.2 3.1 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 OIR56090.1 - 0.11 12.4 4.9 0.91 9.4 5.0 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 OIR56090.1 - 0.12 12.6 4.5 0.19 11.9 4.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Stc1 PF12898.7 OIR56090.1 - 0.14 12.7 4.4 1.5 9.4 1.0 2.3 2 0 0 2 2 2 0 Stc1 domain zf-RING_4 PF14570.6 OIR56090.1 - 0.18 11.6 7.0 3.6 7.5 0.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OIR56090.1 - 0.2 11.7 5.8 6.3 6.9 6.2 2.3 1 1 1 2 2 2 0 Double zinc ribbon Jas PF16135.5 OIR56090.1 - 0.2 11.9 4.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling zf-C3HC4 PF00097.25 OIR56090.1 - 0.28 11.1 7.0 0.61 10.0 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) His_Me_b4a2 PF18275.1 OIR56090.1 - 0.33 11.0 2.3 0.6 10.2 0.2 2.4 1 1 1 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain HNH_5 PF14279.6 OIR56090.1 - 3.3 7.7 5.7 43 4.1 0.5 3.1 2 1 0 2 2 2 0 HNH endonuclease DUF4370 PF14290.6 OIR56091.1 - 0.03 14.2 0.6 0.068 13.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4370) Trypan_PARP PF05887.11 OIR56091.1 - 0.15 12.0 18.4 0.27 11.2 18.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) KIP1 PF07765.12 OIR56091.1 - 0.17 12.0 3.9 0.11 12.7 0.8 2.3 2 0 0 2 2 2 0 KIP1-like protein PH PF00169.29 OIR56092.1 - 0.0057 17.1 0.1 0.017 15.6 0.1 1.9 1 0 0 1 1 1 1 PH domain zf-C3HC4_3 PF13920.6 OIR56093.1 - 0.0061 16.4 4.2 0.01 15.7 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR56093.1 - 0.033 14.5 3.4 0.071 13.5 3.4 1.5 1 0 0 1 1 1 0 Ring finger domain DUF3929 PF13066.6 OIR56093.1 - 0.08 13.0 1.5 0.094 12.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) zf-C3HC4_2 PF13923.6 OIR56093.1 - 3.7 7.5 7.0 0.76 9.7 3.5 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR56094.1 - 0.043 13.7 4.5 0.072 13.0 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF5398 PF17376.2 OIR56094.1 - 0.047 14.3 2.6 0.093 13.4 2.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5398) DUF3929 PF13066.6 OIR56094.1 - 0.098 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) ABC_tran PF00005.27 OIR56095.1 - 2e-12 47.8 0.0 3.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OIR56095.1 - 0.0009 18.7 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OIR56095.1 - 0.0022 17.9 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OIR56095.1 - 0.016 15.5 0.2 0.12 12.6 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 OIR56095.1 - 0.032 14.0 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sec7 PF01369.20 OIR56096.1 - 0.058 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Sec7 domain FAM25 PF15825.5 OIR56096.1 - 0.099 13.0 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 FAM25 family YacG PF03884.14 OIR56097.1 - 1.5e-05 24.6 0.0 13 5.6 0.0 5.3 6 0 0 6 6 6 2 DNA gyrase inhibitor YacG Cu_amine_oxidN2 PF02727.16 OIR56097.1 - 0.0098 16.1 0.3 6.1 7.2 0.0 3.2 3 1 1 4 4 4 2 Copper amine oxidase, N2 domain MlaD PF02470.20 OIR56097.1 - 0.051 13.9 0.0 77 3.7 0.0 3.8 3 1 0 3 3 3 0 MlaD protein Gemin7 PF11095.8 OIR56097.1 - 0.17 11.8 0.5 2 8.4 0.1 2.7 3 0 0 3 3 3 0 Gem-associated protein 7 (Gemin7) RVT_1 PF00078.27 OIR56098.1 - 0.00059 19.4 0.0 0.00073 19.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gcd10p PF04189.13 OIR56099.1 - 0.056 12.6 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Gcd10p family DUF2087 PF09860.9 OIR56099.1 - 0.09 12.9 0.3 4.1 7.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) AAA PF00004.29 OIR56102.1 - 9.9e-37 126.3 0.0 1.7e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR56102.1 - 5.5e-05 22.9 0.1 0.00011 21.9 0.1 1.6 1 1 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OIR56102.1 - 0.0023 18.0 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Reticulon PF02453.17 OIR56105.1 - 0.0042 17.1 0.1 0.0058 16.6 0.1 1.2 1 0 0 1 1 1 1 Reticulon YacG PF03884.14 OIR56107.1 - 0.00041 20.0 0.0 0.095 12.5 0.0 3.1 3 0 0 3 3 3 1 DNA gyrase inhibitor YacG MlaD PF02470.20 OIR56107.1 - 0.17 12.2 0.0 48 4.4 0.0 3.0 3 0 0 3 3 3 0 MlaD protein RVT_1 PF00078.27 OIR56108.1 - 1e-29 103.6 0.1 1.7e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rad33 PF08730.10 OIR56108.1 - 0.028 14.4 0.1 0.078 13.0 0.1 1.7 1 0 0 1 1 1 0 Rad33 Peptidase_Mx1 PF15890.5 OIR56108.1 - 0.085 12.3 1.5 0.27 10.6 0.2 2.3 3 0 0 3 3 3 0 Putative zinc-binding metallo-peptidase FAD_binding_3 PF01494.19 OIR56108.1 - 0.78 8.9 5.7 1.9 7.7 1.6 2.1 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_85 PF03644.13 OIR56110.1 - 0.075 12.4 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Reg_prop PF07494.11 OIR56111.1 - 6.8e-05 22.6 4.4 18 6.0 0.0 6.5 6 0 0 6 6 6 1 Two component regulator propeller Darcynin PF17074.5 OIR56111.1 - 0.00011 22.4 0.0 11 6.3 0.0 4.8 3 2 2 5 5 5 1 Darcynin, domain of unknown function BAF250_C PF12031.8 OIR56111.1 - 0.00023 20.6 1.2 5.1 6.3 0.0 4.7 3 2 1 5 5 5 2 SWI/SNF-like complex subunit BAF250/Osa DUF1561 PF07598.11 OIR56111.1 - 0.0016 16.8 0.1 2.2 6.4 0.0 3.8 2 1 2 4 4 4 2 Protein of unknown function (DUF1561) Sep15_SelM PF08806.11 OIR56111.1 - 0.0021 18.2 6.7 4 7.7 0.0 5.5 6 0 0 6 6 6 1 Sep15/SelM redox domain Corona_7 PF02398.16 OIR56111.1 - 0.078 13.6 2.1 42 4.8 0.0 4.4 2 1 3 5 5 5 0 Coronavirus protein 7 rve PF00665.26 OIR56115.1 - 1.8e-14 53.9 0.1 3.2e-14 53.2 0.1 1.4 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR56115.1 - 0.0059 16.4 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Pro_Al_protease PF02983.14 OIR56115.1 - 0.12 12.4 0.4 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Alpha-lytic protease prodomain zf-C3HC4_3 PF13920.6 OIR56117.1 - 2.1e-06 27.5 6.1 4.4e-06 26.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56117.1 - 0.0063 16.6 7.9 0.0085 16.2 5.4 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OIR56117.1 - 0.029 14.2 2.9 0.068 13.0 2.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR56117.1 - 0.32 10.8 8.2 1.2 9.0 8.2 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR56117.1 - 0.49 10.6 6.1 1.2 9.4 6.1 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DZR PF12773.7 OIR56117.1 - 0.65 10.1 7.5 3.9 7.6 6.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 OIR56117.1 - 0.79 9.9 4.1 0.37 11.0 1.2 1.9 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF2197 PF09963.9 OIR56117.1 - 1.1 9.5 7.8 1.8 8.9 5.1 2.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C3HC4_4 PF15227.6 OIR56117.1 - 1.1 9.4 7.4 0.31 11.2 3.0 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 OIR56117.1 - 1.9 8.8 7.7 0.68 10.3 0.3 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4428 PF14471.6 OIR56118.1 - 0.00025 20.9 0.5 0.00063 19.6 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-SNAP50_C PF12251.8 OIR56118.1 - 0.0051 16.5 0.1 0.0081 15.9 0.1 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C4_ClpX PF06689.13 OIR56118.1 - 0.7 9.8 6.9 0.063 13.2 1.8 1.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger E1-E2_ATPase PF00122.20 OIR56119.1 - 2.2e-22 79.5 0.3 5.3e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 OIR56119.1 - 4.5e-13 49.4 0.3 9.7e-13 48.3 0.3 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 OIR56119.1 - 1.6e-05 24.5 0.1 3.3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus WD40_3 PF15911.5 OIR56119.1 - 0.018 15.0 0.1 0.045 13.8 0.1 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF3792 PF12670.7 OIR56119.1 - 0.85 9.8 5.6 0.51 10.5 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) DUF1582 PF07621.11 OIR56120.1 - 0.00031 20.6 0.4 0.81 9.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1582) DUF1582 PF07621.11 OIR56121.1 - 0.00017 21.4 0.4 0.59 10.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1582) Reprolysin_5 PF13688.6 OIR56122.1 - 1.1e-28 100.8 0.2 1.6e-28 100.2 0.2 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OIR56122.1 - 7.7e-26 91.2 0.0 1.1e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OIR56122.1 - 9.7e-21 74.3 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OIR56122.1 - 4.9e-08 33.5 0.0 1.2e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 OIR56122.1 - 0.00013 21.0 0.0 0.00072 18.6 0.0 1.9 1 1 1 2 2 2 1 Peptidase M66 Reprolysin PF01421.19 OIR56122.1 - 0.022 14.7 15.8 0.41 10.5 5.3 3.6 3 1 0 3 3 3 0 Reprolysin (M12B) family zinc metalloprotease NikR_C PF08753.11 OIR56123.1 - 0.026 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 NikR C terminal nickel binding domain Ribosomal_60s PF00428.19 OIR56126.1 - 1.6e-19 70.3 2.6 2.3e-19 69.8 2.6 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arf PF00025.21 OIR56127.1 - 9.7e-06 25.1 0.0 1.2e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 OIR56127.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 OIR56127.1 - 0.0038 17.1 0.0 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 OIR56127.1 - 0.11 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Aa_trans PF01490.18 OIR56128.1 - 4e-19 68.6 29.2 5.1e-18 65.0 28.4 2.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein PAZ_siRNAbind PF12212.8 OIR56129.1 - 0.12 12.2 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 PAZ domain HypA PF01155.19 OIR56130.1 - 0.059 13.4 0.4 0.059 13.4 0.4 1.7 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TerY_C PF15616.6 OIR56130.1 - 0.13 12.3 2.3 0.29 11.3 2.3 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain DNA_RNApol_7kD PF03604.13 OIR56130.1 - 4.4 7.1 10.1 10 5.9 1.5 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit NikR_C PF08753.11 OIR56131.1 - 0.00031 20.8 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 2 NikR C terminal nickel binding domain FHA_2 PF17913.1 OIR56131.1 - 0.0046 17.2 0.0 1.2e+02 3.0 0.0 4.8 4 1 1 5 5 5 0 FHA domain H_kinase_N PF12282.8 OIR56131.1 - 0.037 14.0 0.0 3.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Signal transduction histidine kinase Sh_2 PF17512.2 OIR56131.1 - 0.053 13.3 0.1 40 3.9 0.0 3.6 2 1 1 4 4 4 0 Metapneumovirus Small hydrophobic protein Stomoxyn PF11585.8 OIR56131.1 - 4.5 7.4 10.6 45 4.2 0.2 4.7 5 0 0 5 5 5 0 Insect antimicrobial peptide, stomoxyn zf-C3HC4_3 PF13920.6 OIR56132.1 - 2.7e-05 23.9 8.5 2.7e-05 23.9 8.5 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56132.1 - 0.00011 22.2 5.2 0.00011 22.2 5.2 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR56132.1 - 0.0045 17.3 6.8 0.0045 17.3 6.8 2.4 2 1 1 3 3 3 1 Ring finger domain zf-Di19 PF05605.12 OIR56132.1 - 0.3 11.4 6.9 0.67 10.3 2.1 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE_2 PF02318.16 OIR56132.1 - 0.39 10.9 14.0 0.046 13.9 9.3 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 OIR56132.1 - 0.77 10.0 9.4 0.27 11.4 1.7 2.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OIR56132.1 - 2.3 8.1 16.9 0.2 11.5 8.7 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain DUF4451 PF14616.6 OIR56132.1 - 4.8 7.4 9.4 1.3 9.3 1.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) FANCL_C PF11793.8 OIR56134.1 - 0.01 16.0 0.9 0.016 15.4 0.9 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain C1_1 PF00130.22 OIR56134.1 - 0.012 15.5 1.8 0.024 14.5 1.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 OIR56134.1 - 0.013 15.7 0.7 0.018 15.3 0.7 1.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 OIR56134.1 - 0.023 15.0 1.1 0.079 13.3 1.1 1.9 1 1 1 2 2 2 0 RING-like domain PHD PF00628.29 OIR56134.1 - 0.086 12.7 0.9 0.086 12.7 0.9 1.6 2 0 0 2 2 2 0 PHD-finger DS PF01916.17 OIR56135.1 - 1.4e-113 378.9 0.2 1.6e-113 378.8 0.2 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase E2F_TDP PF02319.20 OIR56136.1 - 1.2e-13 50.8 0.1 2.3e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 OIR56136.1 - 1.8e-12 47.5 0.0 2.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain HTH_47 PF16221.5 OIR56136.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 winged helix-turn-helix TrmB PF01978.19 OIR56136.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sep15_SelM PF08806.11 OIR56138.1 - 0.005 17.0 0.2 0.7 10.1 0.1 2.7 3 0 0 3 3 3 1 Sep15/SelM redox domain TnpV PF14198.6 OIR56138.1 - 0.0081 16.1 1.9 11 6.0 0.2 3.1 2 1 0 3 3 3 2 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR56138.1 - 0.062 13.5 0.0 9.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Two component regulator propeller Nucleic_acid_bd PF13820.6 OIR56138.1 - 0.45 10.4 1.8 14 5.5 0.3 2.4 2 0 0 2 2 2 0 Putative nucleic acid-binding region DUF2380 PF09533.10 OIR56140.1 - 0.039 13.6 1.4 0.051 13.2 0.2 1.7 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) WSK PF03832.13 OIR56140.1 - 2.1 8.1 6.9 12 5.6 0.4 2.4 2 0 0 2 2 2 0 WSK motif zf-C3HC4_3 PF13920.6 OIR56142.1 - 2.8e-05 23.9 7.1 4.4e-05 23.2 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR56142.1 - 0.00085 19.6 8.8 0.0012 19.2 8.8 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OIR56142.1 - 0.00094 19.0 5.6 0.0017 18.1 5.6 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 FYVE_2 PF02318.16 OIR56142.1 - 0.016 15.4 1.1 0.021 15.0 1.1 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_10 PF16685.5 OIR56142.1 - 0.13 12.4 3.9 0.2 11.8 3.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Stc1 PF12898.7 OIR56142.1 - 0.37 11.4 8.8 0.19 12.3 4.3 2.1 1 1 1 2 2 2 0 Stc1 domain zf-C6H2 PF15801.5 OIR56142.1 - 0.76 10.1 6.2 0.26 11.6 2.1 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Sec23_Sec24 PF04810.15 OIR56142.1 - 5.8 7.1 9.0 6.4 6.9 0.0 3.1 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger BAF250_C PF12031.8 OIR56143.1 - 0.066 12.5 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa RVT_1 PF00078.27 OIR56144.1 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OIR56145.1 - 7.2e-30 104.2 0.0 9.9e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2597 PF10772.9 OIR56145.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Nexin_C PF08628.12 OIR56146.1 - 5.1e-11 43.2 0.1 1.6e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Sorting nexin C terminal zf-C2H2_10 PF16588.5 OIR56150.1 - 0.019 14.7 5.2 0.019 14.7 5.2 1.6 2 0 0 2 2 2 0 C2H2 zinc-finger Sec62 PF03839.16 OIR56151.1 - 0.68 9.4 3.6 0.86 9.1 3.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 zf-C3HC4_3 PF13920.6 OIR56153.1 - 7.5e-05 22.5 2.5 0.00011 22.0 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR56153.1 - 0.016 15.5 5.4 0.027 14.8 5.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 OIR56153.1 - 0.021 14.6 5.4 0.034 13.9 5.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OIR56153.1 - 0.052 13.4 4.6 0.17 11.8 4.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OIR56153.1 - 0.074 13.0 5.6 0.14 12.1 5.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 OIR56153.1 - 0.36 10.7 6.4 0.6 10.0 6.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OIR56153.1 - 0.39 10.9 5.7 0.18 12.0 3.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 OIR56153.1 - 1.3 9.0 6.8 1.2 9.1 1.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Pkinase PF00069.25 OIR56154.1 - 3.5e-25 88.9 0.0 2.2e-24 86.3 0.1 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56154.1 - 2.2e-15 56.6 0.0 3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56154.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56154.1 - 0.0033 16.4 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OIR56154.1 - 0.0039 16.8 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OIR56154.1 - 0.01 14.9 0.1 0.014 14.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 OIR56154.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OIR56154.1 - 0.04 13.8 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OIR56154.1 - 0.19 10.7 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase gag-asp_proteas PF13975.6 OIR56155.1 - 9.7e-15 54.9 0.7 5.4e-14 52.5 0.1 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56155.1 - 1.3e-13 51.4 0.1 3.5e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OIR56155.1 - 5.6e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 OIR56155.1 - 1e-07 32.2 0.1 3.4e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.10 OIR56155.1 - 2.2e-05 24.2 0.1 0.00077 19.3 0.0 2.4 1 1 1 2 2 2 2 Aspartyl protease RVT_1 PF00078.27 OIR56155.1 - 2.6e-05 23.8 0.0 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OIR56156.1 - 1.6e-20 73.6 0.0 2.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OIR56158.1 - 1.3e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sep15_SelM PF08806.11 OIR56159.1 - 2.2e-05 24.5 7.8 1.4 9.2 0.1 5.8 7 0 0 7 7 7 2 Sep15/SelM redox domain Reg_prop PF07494.11 OIR56159.1 - 0.00073 19.5 5.0 71 4.2 0.0 6.9 6 0 0 6 6 6 0 Two component regulator propeller DUF1561 PF07598.11 OIR56159.1 - 0.18 10.0 0.2 6.7 4.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1561) BAF250_C PF12031.8 OIR56160.1 - 2e-05 24.0 3.6 0.0048 16.2 0.1 4.1 2 2 3 5 5 5 1 SWI/SNF-like complex subunit BAF250/Osa ANAPC15 PF15243.6 OIR56160.1 - 0.028 14.8 16.9 7.6 7.0 0.2 6.0 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 15 TUDOR_5 PF18359.1 OIR56160.1 - 0.097 12.4 0.1 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 Unpaired PF15972.5 OIR56160.1 - 0.22 11.1 4.6 11 5.5 0.2 4.0 3 2 2 5 5 5 0 Unpaired protein NOC3p PF07540.11 OIR56160.1 - 0.36 11.3 3.3 43 4.7 0.0 4.6 2 1 4 6 6 6 0 Nucleolar complex-associated protein MafB19-deam PF14437.6 OIR56160.1 - 1.2 8.9 4.5 73 3.1 0.0 4.5 1 1 6 7 7 7 0 MafB19-like deaminase Reg_prop PF07494.11 OIR56160.1 - 2.7 8.5 13.0 1.1e+02 3.6 0.0 6.5 8 0 0 8 8 8 0 Two component regulator propeller Pep3_Vps18 PF05131.14 OIR56163.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family DUF4604 PF15377.6 OIR56164.1 - 0.13 12.7 5.0 0.15 12.4 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) zf-CCHC PF00098.23 OIR56166.1 - 1.6e-06 27.9 2.5 3.2e-06 26.9 2.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OIR56166.1 - 0.0038 17.5 0.0 0.0057 16.9 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.6 OIR56166.1 - 0.0096 15.6 0.9 0.0096 15.6 0.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 OIR56166.1 - 0.1 12.6 0.4 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle EXOSC1 PF10447.9 OIR56167.1 - 2.1e-07 31.5 1.2 0.22 12.1 0.0 4.3 1 1 3 4 4 4 3 Exosome component EXOSC1/CSL4 BAF250_C PF12031.8 OIR56167.1 - 1.3e-06 27.9 0.7 0.007 15.7 0.2 3.0 2 1 1 3 3 3 2 SWI/SNF-like complex subunit BAF250/Osa Sep15_SelM PF08806.11 OIR56167.1 - 0.0058 16.8 0.1 0.0058 16.8 0.1 4.3 4 1 1 5 5 5 1 Sep15/SelM redox domain Eco57I PF07669.11 OIR56167.1 - 0.02 15.4 7.2 10 6.7 0.0 4.6 1 1 4 5 5 5 0 Eco57I restriction-modification methylase TbpB_C PF17483.2 OIR56167.1 - 0.048 14.0 2.7 3.8 7.9 0.0 2.9 2 1 1 3 3 3 0 C-lobe handle domain of Tf-binding protein B PPTA PF01239.22 OIR56167.1 - 0.049 13.4 4.8 1.1 9.0 0.1 3.9 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat EFhand_Ca_insen PF08726.10 OIR56167.1 - 0.091 12.9 2.5 45 4.2 0.0 3.8 4 0 0 4 4 4 0 Ca2+ insensitive EF hand DUF4186 PF13811.6 OIR56167.1 - 0.15 12.1 4.6 34 4.5 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4186) Phage_Gp17 PF17549.2 OIR56167.1 - 0.28 11.2 11.4 1.3 9.1 0.3 3.7 1 1 2 4 4 4 0 Gene Product 17 Nebulin PF00880.18 OIR56167.1 - 0.34 10.9 2.0 46 4.1 0.0 3.8 4 0 0 4 4 4 0 Nebulin repeat ANAPC15 PF15243.6 OIR56167.1 - 0.35 11.3 6.6 30 5.1 0.1 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 15 DUF4492 PF14899.6 OIR56167.1 - 0.83 9.6 13.7 5.6 7.0 0.5 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4492) PriC PF07445.12 OIR56172.1 - 0.0016 18.4 0.8 0.0017 18.3 0.8 1.1 1 0 0 1 1 1 1 Primosomal replication protein priC Exo_endo_phos PF03372.23 OIR56175.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR56175.1 - 0.0024 17.7 0.0 0.0062 16.4 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Fib_alpha PF08702.10 OIR56177.1 - 0.5 10.5 4.0 0.79 9.9 1.4 1.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 OIR56177.1 - 0.93 10.2 6.0 1 10.0 3.3 2.5 1 1 1 2 2 2 0 SlyX V_ATPase_I PF01496.19 OIR56177.1 - 2 6.2 3.4 2.5 5.9 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 OIR56177.1 - 3.1 7.1 12.6 3.7 6.8 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 OIR56177.1 - 4.4 6.0 6.4 5.2 5.8 6.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter YacG PF03884.14 OIR56181.1 - 0.00031 20.4 0.0 5.7 6.8 0.0 3.9 4 0 0 4 4 4 3 DNA gyrase inhibitor YacG DUF1487 PF07368.11 OIR56181.1 - 0.0057 16.1 0.1 2.1 7.7 0.0 2.9 1 1 1 3 3 3 2 Protein of unknown function (DUF1487) MRP-S35 PF10246.9 OIR56181.1 - 0.095 12.7 0.2 40 4.2 0.0 3.6 1 1 3 4 4 4 0 Mitochondrial ribosomal protein MRP-S35 SpoIID PF08486.10 OIR56181.1 - 0.29 11.7 4.7 23 5.7 0.0 4.1 5 0 0 5 5 5 0 Stage II sporulation protein YacG PF03884.14 OIR56182.1 - 0.018 14.8 0.0 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG tRNA-synt_1b PF00579.25 OIR56183.1 - 0.1 11.9 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 OIR56184.1 - 1.3e-58 198.6 0.0 1.6e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 OIR56184.1 - 0.15 10.9 0.1 6 5.7 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (K) HEPN_RiboL-PSP PF18735.1 OIR56185.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 RiboL-PSP-HEPN DUF1444 PF07285.11 OIR56187.1 - 0.046 13.3 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) rve PF00665.26 OIR56188.1 - 5.1e-28 97.7 0.0 8.2e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR56188.1 - 3e-05 23.7 0.0 0.00013 21.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OIR56188.1 - 0.00026 21.2 0.0 0.00042 20.6 0.0 1.3 1 0 0 1 1 1 1 DDE domain DDE_3 PF13358.6 OIR56188.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Pkinase PF00069.25 OIR56189.1 - 2.4e-34 118.9 1.3 7.6e-34 117.3 1.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56189.1 - 4.7e-19 68.7 0.3 7e-19 68.1 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56189.1 - 0.00083 18.8 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56189.1 - 0.0015 18.2 0.5 0.0032 17.1 0.5 1.6 1 1 0 1 1 1 1 RIO1 family EcKinase PF02958.20 OIR56189.1 - 0.0085 15.4 0.4 0.06 12.6 0.0 2.1 1 1 1 2 2 2 1 Ecdysteroid kinase FTA2 PF13095.6 OIR56189.1 - 0.046 13.3 0.3 1.7 8.2 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OIR56189.1 - 0.054 13.4 0.1 0.6 10.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family CagY_M PF07337.11 OIR56189.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 DC-EC Repeat Kinase-like PF14531.6 OIR56189.1 - 0.15 11.4 0.1 0.34 10.2 0.0 1.6 1 1 1 2 2 2 0 Kinase-like RVT_1 PF00078.27 OIR56191.1 - 1.1e-21 77.4 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 OIR56193.1 - 1.4e-27 96.7 0.3 3.6e-27 95.4 0.2 1.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56193.1 - 3.1e-13 49.6 0.1 3.6e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56193.1 - 6.4e-08 32.2 0.3 9.4e-08 31.7 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56193.1 - 0.00055 19.6 0.2 0.0023 17.6 0.2 1.9 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OIR56193.1 - 0.0006 19.5 0.0 0.77 9.3 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OIR56193.1 - 0.0031 16.5 0.1 0.0046 16.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56193.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR56193.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 2 0 0 2 2 2 0 Kinase-like SpoIID PF08486.10 OIR56195.1 - 0.00035 21.0 1.3 2.1 8.9 0.0 5.2 6 0 0 6 6 6 1 Stage II sporulation protein MlaD PF02470.20 OIR56195.1 - 0.00045 20.4 0.1 15 6.0 0.0 5.1 5 1 0 5 5 5 1 MlaD protein FHA_2 PF17913.1 OIR56195.1 - 0.012 15.8 0.0 1.2e+02 3.1 0.0 4.9 4 2 0 4 4 4 0 FHA domain Peptidase_C1 PF00112.23 OIR56195.1 - 0.05 13.7 0.1 55 3.7 0.0 3.8 2 2 2 4 4 4 0 Papain family cysteine protease DUF3929 PF13066.6 OIR56198.1 - 0.058 13.4 0.8 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) zf-C3HC4_3 PF13920.6 OIR56198.1 - 0.16 11.9 4.6 0.38 10.6 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipoprotein_20 PF13942.6 OIR56199.1 - 0.17 11.8 0.0 5.9 6.8 0.0 2.1 2 0 0 2 2 2 0 YfhG lipoprotein GAF_3 PF13492.6 OIR56200.1 - 0.037 14.4 0.1 0.057 13.8 0.1 1.3 1 0 0 1 1 1 0 GAF domain DUF1366 PF07104.11 OIR56200.1 - 0.11 12.2 2.0 0.18 11.5 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) SKA1 PF07160.12 OIR56200.1 - 0.15 11.9 7.9 0.18 11.6 7.9 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 YkyA PF10368.9 OIR56200.1 - 0.35 10.5 7.8 0.42 10.3 7.8 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Peptidase_S46 PF10459.9 OIR56200.1 - 3.5 6.1 7.6 4.1 5.9 7.6 1.0 1 0 0 1 1 1 0 Peptidase S46 zf-RVT PF13966.6 OIR56201.1 - 0.0049 17.5 0.3 0.012 16.3 0.0 1.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase ERCC4 PF02732.15 OIR56202.1 - 2.9e-16 60.0 0.2 6.6e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 OIR56202.1 - 5.9e-05 23.3 0.2 0.0002 21.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Aminotran_1_2 PF00155.21 OIR56203.1 - 0.0088 15.3 0.0 0.0088 15.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PilI PF10623.9 OIR56203.1 - 0.15 12.2 0.7 0.24 11.5 0.7 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer protein PilI zf-UDP PF14569.6 OIR56204.1 - 1 9.5 7.4 2.3 8.4 6.9 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF1561 PF07598.11 OIR56205.1 - 8.2e-05 21.0 0.1 0.31 9.2 0.0 3.8 3 1 1 4 4 4 3 Protein of unknown function (DUF1561) Reg_prop PF07494.11 OIR56205.1 - 0.017 15.2 12.9 9.6 6.8 0.0 6.3 7 0 0 7 7 7 0 Two component regulator propeller Darcynin PF17074.5 OIR56205.1 - 0.14 12.4 0.0 19 5.5 0.0 3.4 3 1 0 3 3 3 0 Darcynin, domain of unknown function Unpaired PF15972.5 OIR56205.1 - 1.9 8.0 8.1 8.5 5.8 0.1 4.0 3 2 1 5 5 5 0 Unpaired protein RVT_1 PF00078.27 OIR56206.1 - 7.5e-05 22.4 0.0 8.7e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 OIR56209.1 - 4.3e-07 30.1 0.0 6.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OIR56209.1 - 8.7e-06 25.6 1.7 8.7e-06 25.6 1.7 1.7 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.6 OIR56209.1 - 0.00088 19.8 0.1 0.0026 18.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56209.1 - 0.0044 17.6 0.0 0.02 15.5 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC_4 PF14392.6 OIR56209.1 - 0.011 15.5 1.2 0.023 14.4 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OIR56209.1 - 0.023 14.6 1.1 0.05 13.6 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.10 OIR56209.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_2 PF13696.6 OIR56209.1 - 0.059 13.2 0.6 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 OIR56209.1 - 0.14 12.5 0.0 0.37 11.1 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease SbcCD_C PF13558.6 OIR56210.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Myb_DNA-bind_5 PF13873.6 OIR56212.1 - 6.4e-05 22.9 10.7 0.015 15.4 1.3 3.3 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain Swi5 PF07061.11 OIR56212.1 - 0.017 15.2 1.4 0.14 12.2 0.9 2.8 2 0 0 2 2 2 0 Swi5 Myb_DNA-bind_3 PF12776.7 OIR56212.1 - 8.9 7.4 7.1 38 5.4 0.0 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.27 OIR56213.1 - 2e-17 63.4 0.0 3.6e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_3 PF01494.19 OIR56213.1 - 0.76 8.9 5.8 2 7.6 1.7 2.1 2 0 0 2 2 2 0 FAD binding domain YcxB PF14317.6 OIR56214.1 - 0.017 14.8 0.5 0.69 9.7 0.2 2.6 2 0 0 2 2 2 0 YcxB-like protein DUF4538 PF15061.6 OIR56214.1 - 0.039 13.7 0.0 16 5.3 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) GDPD PF03009.17 OIR56214.1 - 0.044 13.5 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Nuc_sug_transp PF04142.15 OIR56214.1 - 0.52 9.4 2.2 1.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Nucleotide-sugar transporter OrfB_Zn_ribbon PF07282.11 OIR56214.1 - 6.2 6.8 14.9 0.92 9.5 1.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain CNOT1_TTP_bind PF16417.5 OIR56215.1 - 4.7e-06 25.9 0.1 9.4e-06 24.9 0.1 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain SAM_PNT PF02198.16 OIR56215.1 - 0.087 12.8 0.1 1.5 8.9 0.1 2.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain ArsA_ATPase PF02374.15 OIR56216.1 - 4.8e-64 216.5 0.2 5.3e-64 216.3 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA PF00004.29 OIR56217.1 - 2.1e-41 141.5 0.0 5.5e-41 140.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OIR56217.1 - 9.3e-23 80.0 0.0 1.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 OIR56217.1 - 7.8e-08 32.0 0.0 2.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OIR56217.1 - 4.6e-05 23.9 0.1 0.0061 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OIR56217.1 - 5.4e-05 23.0 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OIR56217.1 - 6.4e-05 23.0 0.0 0.00023 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OIR56217.1 - 9.5e-05 22.7 0.4 0.086 13.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.13 OIR56217.1 - 0.00016 21.0 0.0 0.0004 19.7 0.0 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 OIR56217.1 - 0.00072 19.2 0.3 0.038 13.6 0.1 2.3 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OIR56217.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 OIR56217.1 - 0.0029 17.0 0.1 1.8 7.8 0.0 2.5 1 1 0 2 2 2 2 KaiC DUF815 PF05673.13 OIR56217.1 - 0.0033 16.6 0.0 0.0052 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OIR56217.1 - 0.0074 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OIR56217.1 - 0.009 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OIR56217.1 - 0.0096 16.5 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR56217.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OIR56217.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 OIR56217.1 - 0.02 15.3 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 OIR56217.1 - 0.028 14.1 0.0 3.2 7.4 0.0 2.4 1 1 1 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 OIR56217.1 - 0.03 13.7 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OIR56217.1 - 0.046 14.1 0.1 0.15 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OIR56217.1 - 0.079 12.4 0.2 0.42 10.0 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 OIR56217.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 OIR56217.1 - 0.2 10.9 0.2 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain OCRL_clath_bd PF16726.5 OIR56218.1 - 0.023 14.9 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain Sdh5 PF03937.16 OIR56218.1 - 0.086 12.8 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase DUF1654 PF07867.11 OIR56219.1 - 0.025 14.3 0.1 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Allantoicase PF03561.15 OIR56220.1 - 0.079 12.9 0.1 0.18 11.8 0.1 1.7 1 1 0 1 1 1 0 Allantoicase repeat FHA_2 PF17913.1 OIR56221.1 - 0.0056 16.9 0.0 85 3.5 0.0 4.2 2 1 1 4 4 4 3 FHA domain EXOSC1 PF10447.9 OIR56222.1 - 0.00057 20.5 0.1 5.3 7.7 0.0 3.9 2 1 2 4 4 4 3 Exosome component EXOSC1/CSL4 GFRP PF06399.13 OIR56223.1 - 0.061 13.2 0.1 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Peptidase_M24_C PF16188.5 OIR56223.1 - 0.089 12.9 1.3 15 5.8 0.1 2.6 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 rve PF00665.26 OIR56227.1 - 2.4e-21 76.1 0.0 5.8e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OIR56227.1 - 3.3e-20 72.3 0.1 7.4e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OIR56227.1 - 6.4e-15 55.0 0.2 1.2e-14 54.2 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OIR56227.1 - 7.1e-12 45.2 0.1 1.6e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OIR56227.1 - 1.9e-08 34.4 0.1 5.1e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 H2C2 zinc finger MLVIN_C PF18697.1 OIR56227.1 - 0.0014 18.7 0.0 0.0062 16.6 0.0 2.0 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_Tnp_IS1595 PF12762.7 OIR56227.1 - 0.0023 18.0 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 ISXO2-like transposase domain HTH_22 PF13309.6 OIR56227.1 - 0.032 14.3 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 HTH domain rve_3 PF13683.6 OIR56227.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DDE_3 PF13358.6 OIR56227.1 - 0.081 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease NARG2_C PF10505.9 OIR56228.1 - 0.12 11.9 0.2 5.5 6.4 0.0 2.5 2 1 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Xlink PF00193.17 OIR56228.1 - 0.21 12.0 0.9 89 3.6 0.0 3.9 2 1 3 5 5 5 0 Extracellular link domain tRNA-synt_2 PF00152.20 OIR56229.1 - 0.1 11.7 0.2 0.18 10.9 0.2 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) S4 PF01479.25 OIR56231.1 - 2e-06 27.4 0.0 5.3e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 S4 domain Alpha_adaptin_C PF02296.16 OIR56234.1 - 0.021 15.0 0.7 2 8.7 0.0 2.6 2 1 1 3 3 3 0 Alpha adaptin AP2, C-terminal domain McrBC PF10117.9 OIR56234.1 - 0.064 12.4 0.1 0.49 9.5 0.1 2.1 1 1 1 2 2 2 0 McrBC 5-methylcytosine restriction system component Unpaired PF15972.5 OIR56234.1 - 0.08 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Unpaired protein zf-C3HC4_3 PF13920.6 OIR56234.1 - 0.68 9.8 6.2 0.72 9.8 3.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) VID27_N PF17748.1 OIR56237.1 - 2.9e-14 53.3 0.8 2e-11 44.1 0.8 2.0 1 1 0 1 1 1 1 VID27 N-terminal region LRR_4 PF12799.7 OIR56238.1 - 2.9e-39 132.4 27.9 5.9e-08 32.9 2.7 6.8 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OIR56238.1 - 4.5e-24 84.0 27.9 0.00024 20.8 5.9 7.5 3 2 2 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 OIR56238.1 - 8e-22 77.6 8.5 1.1e-08 34.8 1.8 4.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OIR56238.1 - 1.6e-05 24.8 25.4 1.6 9.6 0.2 9.8 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 OIR56238.1 - 0.00031 20.6 16.3 0.84 9.9 0.3 7.1 8 0 0 8 8 8 2 Leucine Rich repeat LRR_2 PF07723.13 OIR56238.1 - 0.036 14.7 1.3 1e+02 3.8 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat CITED PF04487.12 OIR56238.1 - 0.18 11.8 1.8 16 5.5 0.1 2.9 2 1 0 2 2 2 0 CITED CAAP1 PF15335.6 OIR56238.1 - 0.96 10.0 4.2 2.1 8.9 0.1 3.5 4 0 0 4 4 4 0 Caspase activity and apoptosis inhibitor 1 RNA_pol_Rpb5_C PF01191.19 OIR56239.1 - 2e-30 104.5 0.5 2.5e-30 104.1 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain XPG_I PF00867.18 OIR56241.1 - 3.3e-23 81.9 0.1 6.6e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OIR56241.1 - 2.1e-08 34.5 0.3 9.5e-08 32.4 0.3 2.0 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 OIR56241.1 - 2.2e-05 24.0 0.0 4.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing UPF0728 PF15092.6 OIR56241.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 Hydrophobin PF01185.18 OIR56241.1 - 0.15 12.7 0.1 0.27 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal hydrophobin Asr PF06392.11 OIR56241.1 - 0.27 11.7 2.6 0.84 10.1 2.6 1.9 1 0 0 1 1 1 0 Acid shock protein repeat RrnaAD PF00398.20 OIR56242.1 - 1.2e-66 224.5 0.0 1.5e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 OIR56242.1 - 3.2e-05 23.8 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 OIR56242.1 - 4.8e-05 24.0 0.0 0.00013 22.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OIR56242.1 - 0.0039 16.8 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OIR56242.1 - 0.018 15.7 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OIR56242.1 - 0.032 13.5 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 OIR56242.1 - 0.052 13.0 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 OIR56242.1 - 0.055 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OIR56242.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 OIR56242.1 - 0.14 12.9 0.0 0.29 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TFIID-31kDa PF02291.15 OIR56244.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF3545 PF12065.8 OIR56246.1 - 0.00072 19.5 0.1 0.0019 18.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3545) ERM PF00769.19 OIR56247.1 - 0.35 10.6 17.4 0.56 10.0 17.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zip PF02535.22 OIR56247.1 - 1.6 7.9 2.8 1.7 7.7 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OIR56247.1 - 7.9 5.1 6.9 8.4 5.0 6.9 1.1 1 0 0 1 1 1 0 Presenilin LRR_8 PF13855.6 OIR56248.1 - 0.0019 17.9 0.0 0.49 10.2 0.0 4.0 3 0 0 3 3 3 1 Leucine rich repeat DUF3860 PF12976.7 OIR56248.1 - 0.02 14.9 2.0 35 4.5 0.0 5.0 6 1 1 7 7 7 0 Domain of Unknown Function with PDB structure (DUF3860) Gryzun-like PF12742.7 OIR56248.1 - 0.03 14.3 1.5 2.9 8.0 0.1 4.1 4 0 0 4 4 4 0 Gryzun, putative Golgi trafficking TbpB_C PF17483.2 OIR56248.1 - 0.043 14.2 0.1 1.5 9.2 0.0 2.9 3 0 0 3 3 3 0 C-lobe handle domain of Tf-binding protein B ATP-grasp_6 PF18419.1 OIR56248.1 - 0.13 11.9 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp-like domain Alpha_adaptin_C PF02296.16 OIR56249.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain zf-C3HC4_3 PF13920.6 OIR56250.1 - 0.0025 17.7 3.6 0.0047 16.7 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3929 PF13066.6 OIR56250.1 - 0.13 12.3 0.4 0.26 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) zf-RING_4 PF14570.6 OIR56250.1 - 0.42 10.4 6.6 0.69 9.8 5.2 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR56250.1 - 0.47 10.7 6.9 1.3 9.2 6.9 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger PHD PF00628.29 OIR56250.1 - 0.71 9.8 6.6 1.3 9.0 6.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 OIR56250.1 - 1.7 8.9 6.0 0.52 10.5 2.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 OIR56250.1 - 1.7 8.8 5.8 39 4.4 5.9 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR56250.1 - 1.9 8.9 8.3 0.82 10.1 5.6 1.8 2 0 0 2 2 2 0 Ring finger domain 7tm_3 PF00003.22 OIR56251.1 - 5e-13 49.3 23.2 7.1e-13 48.8 23.2 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OIR56251.1 - 0.00024 20.3 0.0 0.00032 19.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GbpA_2 PF18416.1 OIR56252.1 - 0.07 13.4 0.3 0.091 13.1 0.3 1.1 1 0 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 YacG PF03884.14 OIR56253.1 - 0.022 14.5 0.0 6.2 6.6 0.0 4.0 4 1 1 5 5 5 0 DNA gyrase inhibitor YacG Lig_chan-Glu_bd PF10613.9 OIR56253.1 - 0.12 12.6 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site Exo_endo_phos PF03372.23 OIR56254.1 - 4e-05 23.3 0.0 6.4e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR56254.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase CCDC-167 PF15188.6 OIR56255.1 - 0.0049 17.2 1.7 0.012 15.9 1.7 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Exo_endo_phos PF03372.23 OIR56256.1 - 4e-05 23.3 0.0 6.4e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR56256.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 OIR56257.1 - 3.7e-42 144.3 0.0 5.1e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OIR56257.1 - 0.0024 18.6 0.1 0.006 17.3 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase YacG PF03884.14 OIR56258.1 - 6.4e-11 41.8 0.0 2.7 7.8 0.0 7.7 8 0 0 8 8 8 3 DNA gyrase inhibitor YacG FHA_2 PF17913.1 OIR56258.1 - 0.034 14.4 0.0 37 4.6 0.0 4.6 3 3 3 6 6 6 0 FHA domain T4_deiodinase PF00837.17 OIR56258.1 - 0.072 12.4 0.4 9.3 5.5 0.0 2.9 2 1 1 3 3 3 0 Iodothyronine deiodinase Peptidase_C1 PF00112.23 OIR56258.1 - 0.075 13.1 0.4 24 4.9 0.0 4.3 1 1 6 7 7 7 0 Papain family cysteine protease PlyB_C PF18684.1 OIR56258.1 - 0.12 12.1 0.0 2.8 7.6 0.0 2.8 3 1 0 3 3 3 0 Pleurotolysin B C-terminal domain TOM20_plant PF06552.12 OIR56260.1 - 0.0033 17.2 0.2 0.095 12.4 0.1 2.0 1 1 1 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TnpV PF14198.6 OIR56261.1 - 3.8e-05 23.6 6.7 0.31 11.1 0.3 4.2 5 0 0 5 5 5 3 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR56261.1 - 0.0035 17.4 0.0 65 4.3 0.0 5.4 6 0 0 6 6 6 0 Two component regulator propeller DegS PF05384.11 OIR56261.1 - 0.041 13.4 0.1 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 Sensor protein DegS Unpaired PF15972.5 OIR56261.1 - 0.1 12.1 0.2 27 4.2 0.0 3.2 2 1 2 4 4 4 0 Unpaired protein CppA_N PF14506.6 OIR56261.1 - 0.2 11.7 3.4 15 5.7 0.1 3.0 2 1 1 3 3 3 0 CppA N-terminal DUF2161 PF09929.9 OIR56262.1 - 0.066 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) PliI PF16743.5 OIR56263.1 - 0.00011 21.9 0.1 2.8 7.7 0.0 3.4 3 0 0 3 3 3 2 Periplasmic lysozyme inhibitor of I-type lysozyme Alpha_adaptin_C PF02296.16 OIR56263.1 - 0.0017 18.5 2.8 8.1 6.7 0.0 4.5 4 2 1 5 5 5 2 Alpha adaptin AP2, C-terminal domain CHMI PF02962.15 OIR56263.1 - 0.0079 16.5 0.0 12 6.2 0.0 3.6 3 0 0 3 3 3 1 5-carboxymethyl-2-hydroxymuconate isomerase DUF3471 PF11954.8 OIR56263.1 - 0.049 14.1 0.0 1 9.9 0.0 2.8 3 2 1 4 4 4 0 Domain of unknown function (DUF3471) DUF5426 PF17473.2 OIR56263.1 - 0.065 13.5 0.1 0.58 10.4 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5426) DUF2247 PF10004.9 OIR56263.1 - 3.7 7.3 6.3 3.6 7.3 0.2 3.5 3 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2247) zf-RVT PF13966.6 OIR56265.1 - 0.079 13.7 0.1 0.16 12.7 0.1 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase zf_Rg PF17915.1 OIR56265.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.6 1 0 0 1 1 1 0 Reverse gyrase zinc finger Alpha_adaptinC2 PF02883.20 OIR56266.1 - 0.00021 21.6 0.0 0.00046 20.5 0.0 1.6 1 1 0 1 1 1 1 Adaptin C-terminal domain DUF1013 PF06242.11 OIR56266.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) zf-RVT PF13966.6 OIR56267.1 - 0.0085 16.8 0.1 0.014 16.1 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C3HC4_3 PF13920.6 OIR56268.1 - 0.002 17.9 3.9 0.0036 17.1 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR56269.1 - 0.0013 18.6 7.4 0.0013 18.6 7.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TackOD1 PF18551.1 OIR56269.1 - 0.15 11.7 6.3 0.1 12.3 4.5 1.5 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 DZR PF12773.7 OIR56269.1 - 0.81 9.8 8.2 11 6.1 7.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.16 OIR56269.1 - 1 9.6 9.9 1.3 9.3 6.9 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 OIR56269.1 - 3.7 7.6 8.0 11 6.0 7.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain Rhodanese_C PF12368.8 OIR56269.1 - 7.2 7.1 8.8 21 5.6 0.4 2.7 1 1 1 2 2 2 0 Rhodanase C-terminal TB2_DP1_HVA22 PF03134.19 OIR56270.1 - 2e-21 75.7 2.6 2e-21 75.7 2.6 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Helicase_C_2 PF13307.6 OIR56271.1 - 1.8e-21 77.0 0.1 2.2e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain FAM72 PF14976.6 OIR56272.1 - 5.6e-25 88.2 1.9 6.7e-25 87.9 1.9 1.1 1 0 0 1 1 1 1 FAM72 protein PolC_DP2 PF03833.13 OIR56272.1 - 0.2 9.5 2.8 0.24 9.2 2.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Yippee-Mis18 PF03226.14 OIR56272.1 - 0.99 9.6 10.8 5.5 7.2 10.3 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.25 OIR56273.1 - 1.1e-30 106.9 0.2 1.4e-28 100.0 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56273.1 - 4.6e-19 68.7 0.0 6.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56273.1 - 6.1e-06 25.7 0.2 8.9e-06 25.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56273.1 - 0.0026 16.8 0.0 0.0052 15.8 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56273.1 - 0.019 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR56273.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 OIR56273.1 - 0.05 13.2 0.0 0.4 10.3 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EcKinase PF02958.20 OIR56273.1 - 0.051 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 OIR56273.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 OIR56273.1 - 0.18 10.8 0.9 0.76 8.8 0.3 2.0 1 1 0 2 2 2 0 Seadornavirus VP7 Pkinase PF00069.25 OIR56274.1 - 8.2e-30 104.0 0.0 9.5e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56274.1 - 4.8e-13 49.0 0.0 6.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56274.1 - 0.001 18.5 0.1 0.0019 17.6 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR56274.1 - 0.019 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OIR56274.1 - 0.031 13.9 0.2 0.12 12.0 0.1 1.8 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.20 OIR56274.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OIR56274.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 OIR56274.1 - 0.17 11.1 0.0 0.37 10.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like YacG PF03884.14 OIR56276.1 - 9.4e-07 28.5 0.0 4.7 7.0 0.0 5.9 6 0 0 6 6 6 2 DNA gyrase inhibitor YacG SOR PF07682.11 OIR56276.1 - 4.5e-06 25.8 1.3 2.4 7.0 0.0 4.4 2 1 3 5 5 5 3 Sulphur oxygenase reductase ATG11 PF10377.9 OIR56276.1 - 2.4e-05 24.4 0.0 0.12 12.4 0.0 5.0 2 2 1 3 3 3 1 Autophagy-related protein 11 MlaD PF02470.20 OIR56276.1 - 8.7e-05 22.7 0.3 69 3.8 0.0 6.1 6 1 0 6 6 6 0 MlaD protein RecG_wedge PF17191.4 OIR56276.1 - 0.0033 17.1 1.1 1.4 8.5 0.1 3.6 2 1 1 4 4 4 2 RecG wedge domain NO_synthase PF02898.15 OIR56276.1 - 0.014 14.5 0.1 6.5 5.7 0.0 3.6 3 1 1 4 4 4 0 Nitric oxide synthase, oxygenase domain Sh_2 PF17512.2 OIR56276.1 - 0.036 13.8 3.1 3.2 7.5 0.0 4.0 1 1 4 6 6 6 0 Metapneumovirus Small hydrophobic protein Glyco_hydro_49 PF03718.13 OIR56276.1 - 0.048 13.7 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 Mannitol_dh_C PF08125.13 OIR56276.1 - 0.32 10.4 1.6 40 3.6 0.2 3.4 4 0 0 4 4 4 0 Mannitol dehydrogenase C-terminal domain DUF2573 PF10835.8 OIR56278.1 - 0.12 12.7 0.7 7.5 7.0 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2573) zf-C3HC4_3 PF13920.6 OIR56279.1 - 6.6e-06 25.9 9.0 1.2e-05 25.1 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56279.1 - 5.5e-05 22.9 6.9 0.0009 19.1 7.3 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 FAM35_C PF15793.5 OIR56279.1 - 5.7e-05 22.6 1.6 7.1e-05 22.3 1.6 1.2 1 0 0 1 1 1 1 Protein family FAM35, C-terminal zf-RING_2 PF13639.6 OIR56279.1 - 0.00013 22.2 9.1 0.00022 21.5 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain FYVE_2 PF02318.16 OIR56279.1 - 0.0014 18.9 6.1 0.002 18.3 6.1 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR56279.1 - 0.015 15.1 8.0 0.13 12.1 8.2 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Acetyltransf_CG PF14542.6 OIR56279.1 - 0.12 12.5 0.7 0.22 11.7 0.7 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-RING_UBOX PF13445.6 OIR56279.1 - 0.14 12.2 3.2 0.15 12.2 1.5 1.9 1 1 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 OIR56279.1 - 0.78 9.8 6.7 8.3 6.5 6.8 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-CHY PF05495.12 OIR56279.1 - 1.1 9.8 9.4 2.6 8.6 8.7 1.9 1 1 1 2 2 2 0 CHY zinc finger DUF1178 PF06676.11 OIR56279.1 - 1.2 9.5 6.0 0.097 13.1 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-RING_5 PF14634.6 OIR56279.1 - 1.3 9.0 8.1 3.7 7.6 8.1 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-BED PF02892.15 OIR56279.1 - 5.8 7.0 10.8 7.6 6.7 1.2 3.1 1 1 2 3 3 3 0 BED zinc finger HGTP_anticodon PF03129.20 OIR56280.1 - 1.3e-14 54.1 0.2 4.3e-14 52.4 0.2 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OIR56280.1 - 3e-07 30.6 0.0 1.3e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Mor PF08765.11 OIR56281.1 - 0.024 14.6 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Mor transcription activator family YacG PF03884.14 OIR56283.1 - 1.5e-05 24.6 0.0 2.8 7.7 0.0 4.4 4 1 0 4 4 4 3 DNA gyrase inhibitor YacG Pentapeptide_4 PF13599.6 OIR56283.1 - 0.1 12.8 0.0 26 5.1 0.0 3.3 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) Hamartin PF04388.12 OIR56288.1 - 0.75 8.4 9.8 0.83 8.2 9.8 1.0 1 0 0 1 1 1 0 Hamartin protein Asp-B-Hydro_N PF05279.11 OIR56288.1 - 1.6 8.8 25.4 2.2 8.3 25.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Fib_alpha PF08702.10 OIR56288.1 - 1.7 8.8 8.5 0.83 9.8 3.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family VIR_N PF15912.5 OIR56288.1 - 8.8 5.8 10.4 12 5.4 10.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal UPF0020 PF01170.18 OIR56291.1 - 1.2e-11 44.7 0.0 1.6e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 OIR56291.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.3 1 1 0 1 1 1 0 N-6 DNA Methylase MethyltransfD12 PF02086.15 OIR56291.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TLP1_add_C PF18313.1 OIR56291.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain WD40 PF00400.32 OIR56292.1 - 1.9e-14 53.8 11.6 0.00057 20.7 1.8 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR56292.1 - 6.2e-05 23.2 0.6 7.5 6.9 0.3 4.6 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OIR56292.1 - 0.11 11.2 0.0 1.6 7.4 0.0 2.2 3 0 0 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 OIR56292.1 - 0.13 10.9 1.0 0.78 8.3 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 SPC25 PF06703.11 OIR56293.1 - 1.6e-10 41.0 0.0 1.8e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Ima1_N PF09779.9 OIR56294.1 - 3e-07 31.4 8.9 8.1e-06 26.7 8.9 2.1 1 1 0 1 1 1 1 Ima1 N-terminal domain zf-RRPl_C4 PF17026.5 OIR56294.1 - 0.012 15.7 6.4 0.033 14.3 6.4 1.8 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn_Tnp_IS1595 PF12760.7 OIR56294.1 - 0.032 14.2 4.6 0.49 10.4 2.2 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DUF1726 PF08351.11 OIR56295.1 - 2.4e-22 78.7 0.0 7.7e-22 77.0 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Helicase_RecD PF05127.14 OIR56295.1 - 2.4e-12 47.0 0.3 4.5e-12 46.2 0.3 1.5 1 0 0 1 1 1 1 Helicase Smr PF01713.21 OIR56295.1 - 0.017 15.5 0.2 0.056 13.8 0.1 1.9 2 0 0 2 2 2 0 Smr domain PMM PF03332.13 OIR56296.1 - 5.8e-91 304.2 1.7 6.7e-91 304.0 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OIR56296.1 - 1.4e-06 28.3 0.0 2.5e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CTV_P13 PF06922.11 OIR56296.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Citrus tristeza virus P13 protein Trehalose_PPase PF02358.16 OIR56296.1 - 0.04 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase Hydrolase PF00702.26 OIR56296.1 - 0.047 14.0 0.3 0.16 12.2 0.4 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase VSG_B PF13206.6 OIR56297.1 - 1.1 8.5 7.8 1.4 8.1 7.8 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain MRPL52 PF18699.1 OIR56297.1 - 2.2 8.6 9.7 8.5 6.7 6.6 2.9 3 0 0 3 3 3 0 Mitoribosomal protein mL52 gag-asp_proteas PF13975.6 OIR56298.1 - 6.8e-12 45.8 0.0 1.4e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56298.1 - 1.8e-10 41.3 0.1 4.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OIR56298.1 - 0.0049 17.1 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 OIR56298.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 OIR56298.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF1758 PF05585.12 OIR56298.1 - 0.05 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-C2H2_10 PF16588.5 OIR56298.1 - 0.07 12.9 3.6 0.12 12.1 3.6 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger DUF1835 PF08874.10 OIR56300.1 - 0.045 13.9 0.0 4.6 7.5 0.0 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF1835) DUF5097 PF17020.5 OIR56300.1 - 0.067 13.5 1.2 52 4.2 0.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF5097) Med19 PF10278.9 OIR56301.1 - 0.55 10.1 10.1 1.2 9.0 10.1 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4887 PF16228.5 OIR56301.1 - 1.4 9.1 10.5 3.2 7.9 10.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) ATP-synt_E PF05680.12 OIR56301.1 - 2.6 8.4 9.9 0.48 10.8 5.6 2.0 2 0 0 2 2 2 0 ATP synthase E chain RHH_1 PF01402.21 OIR56302.1 - 0.12 12.3 2.8 2.2 8.4 0.0 3.4 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family zf-C3HC4_3 PF13920.6 OIR56303.1 - 0.00068 19.5 10.5 0.0016 18.3 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TnpV PF14198.6 OIR56303.1 - 0.013 15.4 1.1 3.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Transposon-encoded protein TnpV KASH_CCD PF14662.6 OIR56303.1 - 0.099 12.5 5.4 3.8 7.3 0.9 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH zf-RING_2 PF13639.6 OIR56303.1 - 1.7 9.1 13.4 1.4 9.3 11.1 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 OIR56303.1 - 2.4 8.2 10.7 6.1 6.9 10.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain RVP_2 PF08284.11 OIR56304.1 - 4.7e-11 42.6 0.0 7.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OIR56304.1 - 9.1e-10 38.7 0.0 1.6e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 OIR56304.1 - 6.9e-09 36.2 0.0 3e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56304.1 - 3.1e-07 31.0 0.0 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.23 OIR56304.1 - 2.9e-05 23.9 0.7 6.8e-05 22.8 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Glyco_hydro_85 PF03644.13 OIR56306.1 - 0.087 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Plasmo_rep PF12135.8 OIR56307.1 - 0.34 10.5 1.5 0.52 9.9 0.1 1.9 2 0 0 2 2 2 0 Plasmodium repeat family Chitin_synth_2 PF03142.15 OIR56309.1 - 1.4e-27 96.5 0.0 2.1e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase FtsX PF02687.21 OIR56309.1 - 0.14 12.6 0.7 0.4 11.2 0.1 1.9 2 0 0 2 2 2 0 FtsX-like permease family DUF4372 PF14294.6 OIR56309.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Glyco_hydro_19 PF00182.19 OIR56310.1 - 6.6e-11 42.5 0.0 1.1e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Chitinase class I WGG PF10273.9 OIR56311.1 - 1.5e-08 35.1 0.4 1.8e-08 34.9 0.4 1.1 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 FHA_2 PF17913.1 OIR56314.1 - 0.012 15.9 0.1 4.7 7.5 0.0 2.9 2 1 0 2 2 2 0 FHA domain Sh_2 PF17512.2 OIR56314.1 - 0.042 13.6 0.3 0.26 11.0 0.1 2.1 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein YqaJ PF09588.10 OIR56315.1 - 0.097 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain KIP1 PF07765.12 OIR56315.1 - 0.12 12.5 0.4 0.48 10.6 0.4 2.0 1 0 0 1 1 1 0 KIP1-like protein LigB PF02900.18 OIR56319.1 - 0.16 11.0 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase RT_RNaseH PF17917.1 OIR56320.1 - 1e-40 138.2 0.0 2e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OIR56320.1 - 2.7e-29 101.1 0.0 6e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OIR56320.1 - 1.2e-24 86.8 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OIR56320.1 - 1.5e-05 25.0 0.2 3.2e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OIR56320.1 - 0.00015 21.5 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 OIR56320.1 - 0.0017 18.1 0.1 0.0044 16.8 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_IS240 PF13610.6 OIR56320.1 - 0.0029 17.8 0.1 0.0085 16.3 0.1 1.7 1 0 0 1 1 1 1 DDE domain Tex_N PF09371.10 OIR56320.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Peptidase_A17 PF05380.13 OIR56320.1 - 0.091 12.8 0.0 8.7 6.3 0.0 2.7 2 1 0 2 2 2 0 Pao retrotransposon peptidase Fibrinogen_BP PF08017.11 OIR56322.1 - 4.1e-08 32.1 22.5 5.2e-08 31.7 22.5 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein Minor_tail_Z PF06763.11 OIR56322.1 - 3.8e-05 23.6 12.8 0.36 10.6 1.2 4.0 1 1 4 5 5 5 5 Prophage minor tail protein Z (GPZ) GvpK PF05121.12 OIR56322.1 - 0.087 12.9 9.3 0.35 10.9 0.2 3.1 1 1 2 3 3 3 0 Gas vesicle protein K PAS PF00989.25 OIR56322.1 - 1.2 9.1 6.1 7.3 6.6 1.2 2.4 1 1 2 3 3 3 0 PAS fold KAsynt_C_assoc PF16197.5 OIR56322.1 - 5 7.6 11.5 1.4e+02 3.0 9.8 2.4 1 1 1 2 2 2 0 Ketoacyl-synthetase C-terminal extension DDE_Tnp_IS1595 PF12762.7 OIR56323.1 - 0.0084 16.1 1.6 2.7 8.0 0.1 2.4 2 0 0 2 2 2 2 ISXO2-like transposase domain DUF2536 PF10750.9 OIR56323.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Monellin PF09200.10 OIR56324.1 - 0.0035 17.2 0.1 0.15 11.9 0.0 3.2 3 0 0 3 3 3 1 Monellin UPF0220 PF05255.11 OIR56325.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) SpoIID PF08486.10 OIR56326.1 - 0.0042 17.6 0.1 9.7 6.8 0.0 4.2 5 0 0 5 5 5 2 Stage II sporulation protein FHA_2 PF17913.1 OIR56326.1 - 0.0072 16.5 0.0 24 5.2 0.0 5.0 5 1 0 6 6 6 1 FHA domain DUF4448 PF14610.6 OIR56328.1 - 0.049 13.4 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) LolA PF03548.15 OIR56329.1 - 0.035 13.8 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA MAJIN PF15077.6 OIR56330.1 - 0.026 14.3 4.0 0.03 14.1 4.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein CCDC106 PF15794.5 OIR56330.1 - 6.4 6.4 8.1 7.3 6.2 8.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 zinc_ribbon_2 PF13240.6 OIR56331.1 - 0.028 14.2 0.3 0.043 13.6 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-dskA_traR PF01258.17 OIR56331.1 - 0.032 14.2 0.8 0.065 13.2 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger HypA PF01155.19 OIR56331.1 - 0.091 12.8 0.0 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RVT PF13966.6 OIR56331.1 - 0.2 12.4 1.3 0.27 12.0 1.3 1.4 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase RVT_1 PF00078.27 OIR56333.1 - 0.00013 21.6 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sep15_SelM PF08806.11 OIR56334.1 - 0.048 13.8 0.3 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Sep15/SelM redox domain zf-C3HC4_3 PF13920.6 OIR56335.1 - 9e-07 28.7 7.2 1.6e-06 27.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OIR56335.1 - 0.011 15.5 7.5 0.03 14.1 7.5 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OIR56335.1 - 0.034 14.3 6.2 0.047 13.8 5.2 1.7 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 OIR56335.1 - 0.036 14.1 7.0 0.38 10.8 7.5 2.1 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.6 OIR56335.1 - 0.1 12.4 5.7 0.41 10.5 5.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 OIR56335.1 - 0.33 11.3 6.0 1.4 9.3 0.1 2.9 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR56335.1 - 0.4 10.7 8.2 1.3 9.0 8.1 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OIR56335.1 - 1.3 9.2 7.8 0.47 10.6 4.0 2.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.11 OIR56335.1 - 1.6 8.7 4.9 0.66 9.9 1.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF4451 PF14616.6 OIR56335.1 - 2.5 8.3 7.7 1.3 9.2 2.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) zf-CHY PF05495.12 OIR56335.1 - 2.6 8.6 9.0 24 5.5 9.0 2.3 1 1 0 1 1 1 0 CHY zinc finger DUF2197 PF09963.9 OIR56335.1 - 3.7 7.9 8.0 3.8 7.9 5.3 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) CDC45 PF02724.14 OIR56337.1 - 2 6.6 12.2 2.5 6.3 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RIIa PF02197.17 OIR56338.1 - 0.023 14.4 1.3 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Gcd10p PF04189.13 OIR56339.1 - 0.094 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Gcd10p family RVT_1 PF00078.27 OIR56340.1 - 0.0076 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OIR56341.1 - 4.1e-22 78.8 0.0 7.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PSI_integrin PF17205.3 OIR56341.1 - 1.8 8.3 4.4 1.1 9.0 0.1 2.6 3 0 0 3 3 3 0 Integrin plexin domain Exo_endo_phos PF03372.23 OIR56342.1 - 5e-07 29.5 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 OIR56344.1 - 3.1e-33 115.2 0.0 1.6e-32 113.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56344.1 - 1e-19 70.9 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56344.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56344.1 - 0.00098 18.8 0.1 0.0019 17.8 0.1 1.5 1 1 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 OIR56344.1 - 0.014 14.5 0.6 0.31 10.1 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 OIR56344.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OIR56344.1 - 0.032 14.2 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 OIR56344.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 3D PF06725.11 OIR56345.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 3D domain DEAD_2 PF06733.15 OIR56346.1 - 3.2e-23 82.2 2.1 2.2e-15 56.7 0.0 2.4 1 1 1 2 2 2 2 DEAD_2 ResIII PF04851.15 OIR56346.1 - 0.00014 21.9 0.1 0.0013 18.7 0.1 2.5 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OIR56346.1 - 0.0029 17.4 2.1 0.52 10.0 0.0 2.9 3 1 0 3 3 3 2 DEAD/DEAH box helicase Zot PF05707.12 OIR56346.1 - 0.0062 16.2 0.1 0.018 14.7 0.1 1.8 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 OIR56346.1 - 0.085 13.1 0.5 1.6 9.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain zf-C3HC4_3 PF13920.6 OIR56350.1 - 2.1e-06 27.5 8.4 4.5e-06 26.4 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56350.1 - 9.2e-05 22.2 6.1 0.00055 19.7 6.2 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OIR56350.1 - 0.00051 20.3 8.5 0.00051 20.3 8.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 OIR56350.1 - 0.0044 16.8 7.9 0.0044 16.8 7.9 2.6 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR56350.1 - 0.0059 16.8 2.3 0.0059 16.8 2.3 1.9 2 1 0 2 2 2 1 FYVE-type zinc finger zf-RING_UBOX PF13445.6 OIR56350.1 - 0.14 12.2 2.3 0.22 11.6 1.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OIR56350.1 - 0.16 11.9 5.0 0.52 10.2 5.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OIR56350.1 - 0.57 10.4 5.8 0.73 10.0 2.3 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 OIR56350.1 - 0.65 10.1 6.3 34 4.6 7.2 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 OIR56350.1 - 1.7 9.0 7.7 3.3 8.1 0.4 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR56350.1 - 1.8 8.6 9.8 0.51 10.3 6.1 2.1 2 1 0 2 2 2 0 zinc-RING finger domain Cytochrom_CIII PF02085.16 OIR56350.1 - 2.5 8.5 6.8 0.35 11.2 2.3 1.8 2 0 0 2 2 2 0 Class III cytochrome C family zf-4CXXC_R1 PF10497.9 OIR56350.1 - 2.9 8.2 10.0 1.4 9.2 5.5 2.4 2 1 1 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Reg_prop PF07494.11 OIR56352.1 - 1.2e-08 34.1 2.6 0.33 11.3 0.0 4.3 4 0 0 4 4 4 4 Two component regulator propeller BAF250_C PF12031.8 OIR56352.1 - 1.3e-06 27.9 0.0 0.009 15.3 0.0 2.2 1 1 1 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa LtuA PF17446.2 OIR56352.1 - 0.23 11.9 0.3 26 5.3 0.0 2.9 3 0 0 3 3 3 0 Late transcription unit A ATG11 PF10377.9 OIR56354.1 - 0.025 14.6 0.0 0.78 9.8 0.0 3.1 1 1 1 2 2 2 0 Autophagy-related protein 11 DUF1835 PF08874.10 OIR56354.1 - 0.067 13.4 0.0 21 5.3 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1835) Cas9_a PF18470.1 OIR56355.1 - 0.045 13.3 0.3 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Cas9 alpha-helical lobe domain Tmem26 PF09772.9 OIR56355.1 - 0.057 12.8 0.0 2.6 7.3 0.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 26 Flt3_lig PF02947.14 OIR56356.1 - 0.14 12.4 0.8 9 6.5 0.1 2.6 1 1 1 2 2 2 0 flt3 ligand XRN_M PF17846.1 OIR56356.1 - 0.29 10.0 2.4 4.9 6.0 2.4 2.1 1 1 0 1 1 1 0 Xrn1 helical domain SAGA-Tad1 PF12767.7 OIR56357.1 - 9.6e-08 32.1 0.0 1.2e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FAM25 PF15825.5 OIR56358.1 - 0.023 15.0 0.3 0.06 13.7 0.3 1.6 1 0 0 1 1 1 0 FAM25 family Folliculin PF11704.8 OIR56360.1 - 8.4 6.2 7.5 1 9.2 1.8 1.9 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Trypan_PARP PF05887.11 OIR56362.1 - 0.036 14.1 95.6 0.17 11.9 26.8 4.1 2 1 2 4 4 4 0 Procyclic acidic repetitive protein (PARP) zf-SNAP50_C PF12251.8 OIR56363.1 - 0.00067 19.4 0.3 0.0011 18.6 0.3 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal DUF4428 PF14471.6 OIR56363.1 - 0.0048 16.8 0.6 0.014 15.3 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.13 OIR56363.1 - 0.016 15.1 1.6 0.038 13.9 1.6 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger Ribosomal_L22e PF01776.17 OIR56363.1 - 0.18 12.2 0.7 1.3 9.4 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L22e protein family C1_2 PF03107.16 OIR56363.1 - 0.36 11.2 2.0 0.88 9.9 2.0 1.6 1 1 0 1 1 1 0 C1 domain DUF4428 PF14471.6 OIR56364.1 - 0.00014 21.7 0.7 0.0004 20.2 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-SNAP50_C PF12251.8 OIR56364.1 - 0.0054 16.4 0.2 0.0088 15.7 0.2 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C4_ClpX PF06689.13 OIR56364.1 - 0.037 13.9 1.7 0.092 12.6 1.7 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger C1_2 PF03107.16 OIR56364.1 - 0.33 11.3 1.8 0.78 10.1 1.8 1.6 1 1 0 1 1 1 0 C1 domain Trypan_PARP PF05887.11 OIR56365.1 - 0.036 14.1 95.6 0.17 11.9 26.8 4.1 2 1 2 4 4 4 0 Procyclic acidic repetitive protein (PARP) Glyco_transf_8 PF01501.20 OIR56366.1 - 5.4e-08 32.7 1.7 3.9e-05 23.3 1.4 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OIR56366.1 - 0.016 14.6 2.1 0.017 14.5 0.1 2.0 2 0 0 2 2 2 0 Mannosyltransferase putative Gcd10p PF04189.13 OIR56367.1 - 0.042 12.9 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Gcd10p family TadE PF07811.12 OIR56369.1 - 0.32 11.3 0.2 0.32 11.3 0.2 2.1 2 0 0 2 2 2 0 TadE-like protein HMG_box_5 PF14887.6 OIR56370.1 - 0.038 14.0 1.7 0.055 13.5 1.7 1.4 1 1 0 1 1 1 0 HMG (high mobility group) box 5 IPPT PF01715.17 OIR56370.1 - 0.05 13.4 0.2 0.05 13.4 0.2 1.1 1 0 0 1 1 1 0 IPP transferase CDC45 PF02724.14 OIR56371.1 - 4.2 5.5 8.3 5.1 5.3 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3253 PF11625.8 OIR56372.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Pkinase PF00069.25 OIR56373.1 - 7.5e-23 81.2 0.1 1.2e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56373.1 - 2.2e-17 63.2 0.0 3.1e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56373.1 - 9.6e-05 21.8 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56373.1 - 0.031 13.2 0.1 0.039 12.9 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain SBBP PF06739.11 OIR56373.1 - 0.033 14.2 0.1 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 Beta-propeller repeat APH PF01636.23 OIR56373.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 OIR56374.1 - 1.1e-29 103.7 0.0 5.1e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56374.1 - 2.8e-19 69.4 0.0 5.3e-19 68.5 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OIR56374.1 - 6.6e-06 25.6 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56374.1 - 0.0092 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56374.1 - 0.031 14.2 0.1 0.043 13.7 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OIR56374.1 - 0.033 13.8 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 OIR56375.1 - 5.2e-13 49.0 0.0 5.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56375.1 - 3.3e-05 23.3 0.0 4.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OIR56375.1 - 0.063 12.9 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L21e PF01157.18 OIR56375.1 - 0.13 12.1 0.1 2.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L21e PCNA_N PF00705.18 OIR56377.1 - 9.1e-45 151.5 1.0 2.7e-44 149.9 1.3 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OIR56377.1 - 1e-30 106.6 0.1 3e-30 105.0 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 OIR56377.1 - 2.2e-06 26.9 0.1 0.0001 21.5 0.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OIR56377.1 - 4.3e-06 26.4 0.1 5.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 OIR56377.1 - 0.00096 18.3 0.0 0.63 9.1 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein PUA PF01472.20 OIR56378.1 - 2.5e-19 69.0 0.2 3.3e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OIR56378.1 - 0.00023 21.3 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain gag-asp_proteas PF13975.6 OIR56380.1 - 7.2e-07 29.7 0.1 1.5e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56380.1 - 3.3e-06 27.7 0.1 8e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease BAF250_C PF12031.8 OIR56383.1 - 0.0036 16.6 2.4 2 7.7 0.3 3.4 3 0 0 3 3 3 3 SWI/SNF-like complex subunit BAF250/Osa RVT_1 PF00078.27 OIR56385.1 - 1.8e-16 60.4 0.1 1.9e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sld5 PF05916.11 OIR56385.1 - 0.046 14.2 0.7 0.094 13.2 0.7 1.6 1 0 0 1 1 1 0 GINS complex protein zf-C3HC4_3 PF13920.6 OIR56387.1 - 0.00071 19.4 6.7 0.0014 18.5 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56387.1 - 0.017 15.0 6.3 0.036 13.9 6.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UMPH-1 PF05822.12 OIR56387.1 - 0.022 14.3 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) zf-UDP PF14569.6 OIR56387.1 - 0.03 14.4 3.4 0.077 13.1 3.4 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR56387.1 - 0.33 11.2 4.2 1.2 9.4 2.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Sdh5 PF03937.16 OIR56388.1 - 0.013 15.5 0.0 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase OCRL_clath_bd PF16726.5 OIR56388.1 - 0.068 13.4 0.1 0.1 12.8 0.1 1.5 1 1 0 1 1 1 0 Inositol polyphosphate 5-phosphatase clathrin binding domain DUF2540 PF10802.8 OIR56388.1 - 0.1 12.7 1.1 0.22 11.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) Peptidase_M18 PF02127.15 OIR56389.1 - 2e-124 415.7 0.0 2.3e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OIR56389.1 - 9.1e-05 21.6 0.0 0.0045 16.0 0.0 2.4 2 1 0 2 2 2 1 M42 glutamyl aminopeptidase dUTPase PF00692.19 OIR56390.1 - 7.5e-40 135.6 0.0 8.7e-40 135.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase PTAC PF06130.12 OIR56391.1 - 0.039 14.1 0.0 0.43 10.8 0.0 2.2 1 1 1 2 2 2 0 Phosphate propanoyltransferase Glyco_hydro_20b PF02838.15 OIR56391.1 - 0.059 14.2 0.0 0.095 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 BAR_3 PF16746.5 OIR56393.1 - 9.9e-05 22.2 0.5 0.00014 21.7 0.5 1.2 1 0 0 1 1 1 1 BAR domain of APPL family Snf7 PF03357.21 OIR56393.1 - 0.013 15.1 1.0 0.017 14.7 1.0 1.1 1 0 0 1 1 1 0 Snf7 EF-hand_like PF09279.11 OIR56394.1 - 0.12 12.9 7.0 1.3 9.5 3.9 2.5 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like SPRY PF00622.28 OIR56395.1 - 1.1e-22 80.4 0.4 1.6e-22 79.8 0.4 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 OIR56395.1 - 1.9e-17 63.5 0.2 4.1e-17 62.4 0.0 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain BAF250_C PF12031.8 OIR56396.1 - 1.4e-07 31.1 8.8 0.35 10.1 0.0 6.7 3 2 2 6 6 6 3 SWI/SNF-like complex subunit BAF250/Osa Reg_prop PF07494.11 OIR56396.1 - 0.0022 18.0 6.4 1.3e+02 3.4 0.0 7.4 9 0 0 9 9 9 0 Two component regulator propeller PSP PF04046.16 OIR56396.1 - 0.005 16.7 0.3 84 3.2 0.0 4.9 5 0 0 5 5 5 0 PSP TnpV PF14198.6 OIR56396.1 - 0.028 14.4 22.6 2.4 8.2 0.4 8.5 6 4 1 7 7 7 0 Transposon-encoded protein TnpV Thioredoxin_3 PF13192.6 OIR56396.1 - 0.048 13.7 0.3 18 5.5 0.0 4.4 5 0 0 5 5 5 0 Thioredoxin domain Gemini_AC4_5 PF04807.12 OIR56396.1 - 0.14 11.8 1.5 1e+02 2.7 0.0 4.3 4 0 0 4 4 4 0 Geminivirus AC4/5 conserved region GerD PF17898.1 OIR56396.1 - 0.17 11.8 1.8 9 6.3 0.0 3.5 4 0 0 4 4 4 0 Spore germination GerD central core domain ANAPC15 PF15243.6 OIR56396.1 - 0.66 10.4 14.4 19 5.7 0.0 7.1 9 0 0 9 9 9 0 Anaphase-promoting complex subunit 15 Nuc_sug_transp PF04142.15 OIR56396.1 - 7.6 5.6 14.5 36 3.4 0.0 6.4 4 3 5 9 9 9 0 Nucleotide-sugar transporter ABC_tran PF00005.27 OIR56398.1 - 6.6e-13 49.3 1.4 8.1e-13 49.1 0.1 1.8 2 1 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 OIR56398.1 - 0.00011 22.0 1.6 0.00023 20.9 1.1 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_23 PF13476.6 OIR56398.1 - 0.00087 19.8 0.9 0.00087 19.8 0.9 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OIR56398.1 - 0.015 15.2 0.4 0.037 13.9 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OIR56398.1 - 0.023 15.0 0.1 0.058 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OIR56398.1 - 0.044 13.5 0.3 0.088 12.6 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OIR56398.1 - 0.094 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 OIR56398.1 - 0.18 11.2 0.2 0.39 10.1 0.2 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain HEAT_EZ PF13513.6 OIR56399.1 - 0.11 13.0 0.0 1.3 9.6 0.0 2.1 2 0 0 2 2 2 0 HEAT-like repeat DUF4263 PF14082.6 OIR56400.1 - 0.086 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) RNA_pol_Rpb4 PF03874.16 OIR56401.1 - 0.082 13.2 6.7 0.8 10.1 0.1 3.5 3 2 1 4 4 4 0 RNA polymerase Rpb4 Orthopox_F7 PF05813.12 OIR56401.1 - 0.55 10.4 2.7 1.6 8.9 0.1 3.1 2 2 2 4 4 4 0 Orthopoxvirus F7 protein KH_1 PF00013.29 OIR56403.1 - 3.4e-09 36.4 2.2 0.0071 16.2 0.0 5.6 6 0 0 6 6 6 3 KH domain HTH_DeoR PF08220.12 OIR56403.1 - 0.1 12.3 0.2 0.5 10.2 0.0 2.2 3 0 0 3 3 3 0 DeoR-like helix-turn-helix domain STPPase_N PF16891.5 OIR56403.1 - 0.12 12.8 1.1 19 5.8 0.1 3.2 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain NEMO PF11577.8 OIR56403.1 - 3.9 7.6 5.6 12 6.0 0.0 3.3 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO zf-C3HC4_3 PF13920.6 OIR56404.1 - 0.00096 19.0 3.0 0.0018 18.1 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56404.1 - 0.46 10.6 1.8 0.94 9.6 1.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger LRR_8 PF13855.6 OIR56404.1 - 0.79 9.5 4.8 57 3.6 0.1 4.6 3 1 1 4 4 4 0 Leucine rich repeat Unpaired PF15972.5 OIR56404.1 - 0.83 9.1 5.0 76 2.7 0.1 4.6 3 2 2 6 6 6 0 Unpaired protein DUF2714 PF10896.8 OIR56404.1 - 7.4 6.6 9.3 14 5.7 0.1 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2714) T4_deiodinase PF00837.17 OIR56405.1 - 0.096 12.0 0.2 1.8 7.8 0.1 2.2 1 1 1 2 2 2 0 Iodothyronine deiodinase DUF1447 PF07288.11 OIR56405.1 - 0.1 12.7 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) Flu_M1 PF00598.19 OIR56406.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Influenza Matrix protein (M1) HDV_ag PF01517.18 OIR56407.1 - 1.4 8.7 3.4 9.6 5.9 0.1 3.4 4 0 0 4 4 4 0 Hepatitis delta virus delta antigen Disintegrin PF00200.23 OIR56408.1 - 1.6e-10 41.6 25.0 1.6e-10 41.6 25.0 3.3 2 1 0 2 2 2 1 Disintegrin CBF PF03914.17 OIR56409.1 - 1.9e-08 34.5 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 CBF/Mak21 family V-ATPase_H_N PF03224.14 OIR56409.1 - 0.02 14.2 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 V-ATPase subunit H RNA_pol_Rpb1_1 PF04997.12 OIR56410.1 - 1.2e-34 120.0 0.0 1.5e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DUF2180 PF09947.9 OIR56410.1 - 0.0076 16.2 1.8 0.018 15.0 1.8 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2180) Prot_inhib_II PF02428.15 OIR56410.1 - 0.11 13.0 2.3 1.8 9.1 0.1 2.5 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family Fip1 PF05182.13 OIR56411.1 - 6e-22 76.9 0.3 1.1e-21 76.1 0.3 1.5 1 0 0 1 1 1 1 Fip1 motif PBP_sp32 PF07222.12 OIR56412.1 - 2.9 7.3 7.8 3.6 7.0 7.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 TPR_2 PF07719.17 OIR56413.1 - 1e-15 56.5 16.5 8.4e-06 25.5 0.0 6.9 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OIR56413.1 - 1.8e-15 56.0 18.2 2.7e-06 26.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 OIR56413.1 - 4e-15 56.2 0.8 3.7e-06 27.5 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OIR56413.1 - 2.8e-12 46.1 3.7 1e-07 31.5 0.6 3.7 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 OIR56413.1 - 1.7e-11 43.4 15.2 8e-05 22.6 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 OIR56413.1 - 1.7e-11 43.9 5.4 0.0011 19.7 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 OIR56413.1 - 1.3e-09 37.8 0.8 0.027 14.8 0.1 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OIR56413.1 - 4.8e-08 33.4 1.5 0.00037 20.9 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR56413.1 - 5.6e-07 29.7 11.8 0.00027 21.1 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OIR56413.1 - 2.7e-06 27.6 4.8 0.013 15.7 0.0 4.5 3 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC8 PF04049.13 OIR56413.1 - 2.3e-05 24.5 1.6 5.3e-05 23.3 0.8 2.1 1 1 1 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_7 PF13176.6 OIR56413.1 - 0.0002 21.2 3.3 0.051 13.6 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OIR56413.1 - 0.00044 20.7 10.6 9 7.2 0.2 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OIR56413.1 - 0.00079 18.7 0.4 0.0039 16.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat BAR_3 PF16746.5 OIR56415.1 - 4.9e-05 23.2 0.3 7e-05 22.7 0.3 1.3 1 0 0 1 1 1 1 BAR domain of APPL family SCP-1 PF05483.12 OIR56415.1 - 0.0013 16.8 1.2 0.0014 16.7 1.2 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) SKA1 PF07160.12 OIR56415.1 - 0.02 14.8 0.4 0.02 14.8 0.4 1.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DASH_Spc34 PF08657.10 OIR56415.1 - 0.04 13.7 0.2 0.04 13.7 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 C_Hendra PF16821.5 OIR56416.1 - 0.092 12.6 0.9 0.12 12.2 0.9 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses DUF3606 PF12244.8 OIR56417.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) zf-4CXXC_R1 PF10497.9 OIR56418.1 - 0.45 10.8 4.0 4.3 7.6 1.6 2.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 CaMKII_AD PF08332.10 OIR56420.1 - 0.14 12.3 0.1 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Calcium/calmodulin dependent protein kinase II association domain Pkinase PF00069.25 OIR56421.1 - 1.3e-18 67.3 0.1 2.3e-17 63.3 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56421.1 - 1.7e-06 27.5 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OIR56423.1 - 9.2e-32 110.4 0.0 1.4e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 OIR56423.1 - 8.7e-25 87.3 0.0 1.4e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 OIR56423.1 - 3.7e-14 52.6 0.0 5.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR56423.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 OIR56424.1 - 5e-37 127.7 1.6 1.3e-36 126.3 1.5 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56424.1 - 1.7e-18 66.9 0.4 2.4e-18 66.4 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56424.1 - 3.1e-08 33.2 0.1 4.7e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56424.1 - 1.8e-05 23.8 0.1 2.4e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RICTOR_M PF14666.6 OIR56424.1 - 0.096 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain BET PF17035.5 OIR56424.1 - 2.7 8.2 4.9 13 6.0 0.7 2.3 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Pkinase PF00069.25 OIR56425.1 - 8.8e-10 38.4 0.0 1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56425.1 - 0.0016 17.7 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OIR56426.1 - 2.3e-33 115.7 0.8 5.4e-33 114.5 1.1 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56426.1 - 2.2e-18 66.5 0.2 3.1e-18 66.0 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56426.1 - 0.0013 18.2 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56426.1 - 0.015 14.9 0.1 0.031 13.9 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OIR56426.1 - 0.041 13.5 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OIR56426.1 - 0.17 11.8 0.0 0.51 10.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cep57_MT_bd PF06657.13 OIR56427.1 - 0.032 14.7 0.1 0.073 13.5 0.1 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Exo_endo_phos PF03372.23 OIR56428.1 - 2.3e-05 24.1 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OIR56429.1 - 0.0035 18.0 0.1 0.0058 17.3 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Myb_DNA-bind_5 PF13873.6 OIR56430.1 - 0.0059 16.6 1.7 0.0059 16.6 1.7 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain MSA-2c PF12238.8 OIR56432.1 - 3.6 7.5 6.2 0.18 11.8 0.4 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Borrelia_P83 PF05262.11 OIR56432.1 - 5.6 5.3 12.4 7.6 4.9 12.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MlaD PF02470.20 OIR56434.1 - 1.6e-06 28.3 0.0 12 6.3 0.0 5.3 4 1 1 5 5 5 2 MlaD protein PilM PF07419.12 OIR56434.1 - 0.00038 20.6 0.0 21 5.3 0.0 3.7 4 0 0 4 4 4 0 PilM zf-C3HC4_3 PF13920.6 OIR56434.1 - 0.0012 18.6 5.7 0.0024 17.7 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MHC_I_3 PF16497.5 OIR56434.1 - 0.0023 17.4 0.5 9.8 5.6 0.0 4.2 2 1 3 5 5 5 1 MHC-I family domain H2TH PF06831.14 OIR56434.1 - 0.0092 15.9 1.4 14 5.8 0.0 3.8 4 0 0 4 4 4 2 Formamidopyrimidine-DNA glycosylase H2TH domain zf-UDP PF14569.6 OIR56434.1 - 0.031 14.4 3.9 0.066 13.3 3.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OIR56434.1 - 0.031 14.1 6.3 0.078 12.9 6.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SbsC_C PF18058.1 OIR56434.1 - 0.068 13.4 1.0 44 4.3 0.1 3.8 2 1 2 4 4 4 0 SbsC C-terminal domain HEPN_RES_NTD1 PF18870.1 OIR56434.1 - 1.6 8.9 5.7 52 4.0 0.0 4.4 2 1 3 5 5 5 0 HEPN/RES N-terminal domain 1 zf-RING_5 PF14634.6 OIR56434.1 - 2.6 8.1 7.5 12 6.0 7.6 2.1 1 1 0 1 1 1 0 zinc-RING finger domain RVT_1 PF00078.27 OIR56437.1 - 2e-33 115.8 0.0 2.4e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpa2_4 PF06883.12 OIR56438.1 - 0.11 12.5 0.0 9 6.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I, Rpa2 specific domain Ribosomal_S4e PF00900.20 OIR56439.1 - 0.069 13.1 18.5 5.7 6.9 0.1 7.2 8 0 0 8 8 8 0 Ribosomal family S4e Sep15_SelM PF08806.11 OIR56439.1 - 0.096 12.9 22.8 3.6 7.8 0.2 7.1 7 1 1 8 8 8 0 Sep15/SelM redox domain DUF2808 PF10989.8 OIR56439.1 - 0.12 12.4 0.1 31 4.5 0.0 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF2808) Ribosomal_L33 PF00471.20 OIR56439.1 - 0.55 10.7 0.1 0.55 10.7 0.1 4.6 6 0 0 6 6 6 0 Ribosomal protein L33 DUF1118 PF06549.12 OIR56439.1 - 2.8 8.3 10.8 19 5.6 0.1 4.7 2 1 3 5 5 5 0 Protein of unknown function (DUF1118) RFC1 PF08519.12 OIR56439.1 - 4.9 7.3 9.0 65 3.6 0.0 5.0 5 2 1 6 6 6 0 Replication factor RFC1 C terminal domain RVT_1 PF00078.27 OIR56441.1 - 1.6e-40 139.0 0.0 2.1e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_3 PF13920.6 OIR56442.1 - 2.9e-05 23.8 7.3 6e-05 22.8 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56442.1 - 0.0095 16.0 5.3 0.019 15.0 5.3 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR56442.1 - 0.011 16.0 4.7 0.012 15.8 3.9 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 OIR56442.1 - 0.011 15.6 5.1 0.036 13.9 5.1 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-XS PF03470.14 OIR56442.1 - 0.15 12.4 0.8 0.27 11.5 0.8 1.4 1 0 0 1 1 1 0 XS zinc finger domain zf-RING_5 PF14634.6 OIR56442.1 - 0.46 10.5 7.9 2 8.4 8.0 2.1 1 1 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 OIR56442.1 - 0.53 10.4 3.8 15 5.7 5.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 OIR56442.1 - 1.1 9.4 6.3 0.75 10.0 3.5 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 OIR56442.1 - 1.3 9.4 7.6 3.3 8.1 0.2 2.7 1 1 2 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RecR PF02132.15 OIR56442.1 - 2 8.1 6.7 0.69 9.5 2.8 2.1 2 0 0 2 2 2 0 RecR protein zinc-ribbons_6 PF07191.12 OIR56442.1 - 2.2 8.3 6.9 11 6.1 5.5 2.5 2 1 1 3 3 3 0 zinc-ribbons zf-RING_4 PF14570.6 OIR56442.1 - 2.7 7.8 9.2 66 3.4 9.3 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MlaD PF02470.20 OIR56443.1 - 7.6e-05 22.9 0.0 98 3.3 0.0 6.7 6 3 2 8 8 8 0 MlaD protein Reg_prop PF07494.11 OIR56443.1 - 0.00011 22.0 4.5 13 6.4 0.0 7.5 9 0 0 9 9 9 1 Two component regulator propeller BAF250_C PF12031.8 OIR56443.1 - 0.00014 21.2 0.4 0.51 9.6 0.0 4.1 3 1 1 4 4 4 1 SWI/SNF-like complex subunit BAF250/Osa Unpaired PF15972.5 OIR56443.1 - 0.00072 19.2 2.2 2.2 7.8 0.0 3.8 3 1 0 3 3 3 2 Unpaired protein Nuc_sug_transp PF04142.15 OIR56443.1 - 0.075 12.2 10.3 22 4.1 0.0 6.3 8 0 0 8 8 8 0 Nucleotide-sugar transporter GcrA PF07750.11 OIR56443.1 - 0.088 13.2 0.4 7.8 6.9 0.0 3.8 5 1 1 6 6 6 0 GcrA cell cycle regulator DUF4380 PF14315.6 OIR56443.1 - 0.098 11.6 0.1 0.8 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4380) ANAPC15 PF15243.6 OIR56443.1 - 0.46 10.9 14.7 34 4.9 0.1 6.6 8 0 0 8 8 8 0 Anaphase-promoting complex subunit 15 DUF2714 PF10896.8 OIR56443.1 - 1.4 9.0 6.7 0.85 9.7 0.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2714) zf-C3HC4_3 PF13920.6 OIR56444.1 - 0.7 9.8 8.3 1.5 8.7 8.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Nuc_sug_transp PF04142.15 OIR56449.1 - 0.36 9.9 0.3 19 4.3 0.1 2.0 1 1 1 2 2 2 0 Nucleotide-sugar transporter zf-C3HC4_3 PF13920.6 OIR56450.1 - 0.0019 18.0 4.3 0.004 17.0 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS1595 PF12760.7 OIR56450.1 - 0.027 14.5 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_5 PF14634.6 OIR56450.1 - 0.037 14.0 3.5 0.073 13.0 3.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Di19 PF05605.12 OIR56450.1 - 0.092 13.1 0.6 0.21 11.9 0.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Prok-RING_4 PF14447.6 OIR56450.1 - 0.15 12.0 1.7 0.36 10.7 1.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OIR56450.1 - 0.23 11.8 3.1 0.49 10.8 3.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 OIR56450.1 - 0.29 10.9 4.5 0.67 9.8 4.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OIR56450.1 - 0.59 10.3 8.0 0.38 10.9 3.3 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger Pkinase PF00069.25 OIR56452.1 - 1.9e-30 106.1 0.0 2.3e-29 102.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56452.1 - 5.2e-19 68.5 0.0 7.3e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56452.1 - 6.9e-06 25.6 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56452.1 - 0.0016 17.5 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OIR56452.1 - 0.0054 16.3 0.4 0.0093 15.6 0.1 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 OIR56452.1 - 0.01 15.4 2.3 0.033 13.8 2.3 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OIR56453.1 - 9.7e-36 123.5 0.5 3.8e-35 121.5 0.9 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56453.1 - 7.7e-20 71.2 0.3 1.1e-19 70.7 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56453.1 - 1.5e-05 24.4 0.2 2.3e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR56453.1 - 0.00025 21.0 0.0 0.0034 17.3 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OIR56453.1 - 0.00041 20.0 0.8 0.0008 19.1 0.8 1.4 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OIR56453.1 - 0.015 14.9 0.0 0.05 13.2 0.0 1.8 2 1 0 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 OIR56453.1 - 0.022 13.7 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Fructosamin_kin PF03881.14 OIR56453.1 - 0.055 12.7 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 Fructosamine kinase zf-C3HC4_3 PF13920.6 OIR56454.1 - 0.0053 16.6 5.1 0.009 15.8 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3795 PF12675.7 OIR56454.1 - 0.13 12.6 2.9 3.4 8.1 2.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Gin PF10764.9 OIR56454.1 - 0.72 9.9 2.8 1.3 9.0 2.8 1.4 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin TbpB_C PF17483.2 OIR56455.1 - 0.053 13.9 6.2 4.8 7.6 0.1 4.0 1 1 2 4 4 4 0 C-lobe handle domain of Tf-binding protein B ADD_DNMT3 PF17980.1 OIR56455.1 - 0.065 13.2 0.2 11 6.2 0.0 2.8 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 EXOSC1 PF10447.9 OIR56455.1 - 0.11 13.2 0.5 3.1 8.4 0.0 3.2 3 2 1 5 5 5 0 Exosome component EXOSC1/CSL4 NusG PF02357.19 OIR56455.1 - 0.12 12.9 2.6 1.4 9.5 0.1 3.0 3 0 0 3 3 3 0 Transcription termination factor nusG zf-C3HC4_3 PF13920.6 OIR56458.1 - 0.00028 20.7 5.5 0.00051 19.8 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56458.1 - 0.019 14.8 6.6 0.041 13.7 6.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Stc1 PF12898.7 OIR56458.1 - 6.9 7.3 8.5 2.1 9.0 4.3 2.1 1 1 1 2 2 2 0 Stc1 domain zf-C6H2 PF15801.5 OIR56458.1 - 7.8 6.9 7.2 1.3 9.4 2.3 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-C3HC4_3 PF13920.6 OIR56460.1 - 0.0092 15.8 1.0 0.019 14.8 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR56460.1 - 0.012 15.9 2.6 0.045 14.1 2.6 2.1 1 0 0 1 1 1 0 Ring finger domain Spt4 PF06093.13 OIR56460.1 - 0.015 15.4 0.7 0.59 10.3 0.2 3.0 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger zf-RING_4 PF14570.6 OIR56460.1 - 0.016 14.9 1.0 0.042 13.7 1.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OIR56460.1 - 0.035 14.0 5.0 1.5 8.7 3.8 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OIR56460.1 - 0.063 13.2 3.0 0.14 12.2 3.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OIR56460.1 - 0.73 10.0 4.0 1.7 8.8 4.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4448 PF14610.6 OIR56461.1 - 0.0072 16.1 0.6 0.098 12.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Cytochrom_C_asm PF01578.20 OIR56461.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein Alpha_GJ PF03229.13 OIR56461.1 - 0.88 10.1 9.8 0.098 13.2 0.8 3.0 1 1 0 2 2 2 0 Alphavirus glycoprotein J BMP2K_C PF15282.6 OIR56462.1 - 0.51 10.1 3.5 0.67 9.8 3.5 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus zf-C3HC4_3 PF13920.6 OIR56471.1 - 1.7e-06 27.8 5.5 3.2e-06 26.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sep15_SelM PF08806.11 OIR56471.1 - 0.00012 22.2 9.3 0.58 10.4 0.1 5.6 4 1 1 5 5 5 1 Sep15/SelM redox domain DUF3860 PF12976.7 OIR56471.1 - 0.034 14.2 0.0 1e+02 3.0 0.0 5.1 7 0 0 7 7 7 0 Domain of Unknown Function with PDB structure (DUF3860) zf-UDP PF14569.6 OIR56471.1 - 0.044 13.9 4.9 0.11 12.6 4.9 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF2197 PF09963.9 OIR56471.1 - 0.22 11.8 3.4 0.8 10.0 3.4 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) MbeB_N PF04837.12 OIR56471.1 - 0.39 11.1 3.6 5.8 7.3 0.1 3.6 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Prok-RING_4 PF14447.6 OIR56471.1 - 1.2 9.0 4.7 2.8 7.9 4.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR56471.1 - 3.3 7.6 8.3 9.5 6.1 8.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TnpV PF14198.6 OIR56471.1 - 6 6.9 13.7 9.5 6.3 0.0 4.9 4 2 1 6 6 6 0 Transposon-encoded protein TnpV DUF3665 PF12427.8 OIR56471.1 - 6.8 6.5 5.6 44 3.9 0.1 3.3 3 0 0 3 3 3 0 Branched-chain amino acid aminotransferase DUF4472 PF14739.6 OIR56473.1 - 0.05 14.4 5.3 0.075 13.8 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) YacG PF03884.14 OIR56474.1 - 0.0011 18.7 0.0 4 7.3 0.0 3.9 4 0 0 4 4 4 2 DNA gyrase inhibitor YacG SCAB-Ig PF16709.5 OIR56474.1 - 0.017 15.2 0.0 33 4.6 0.0 3.6 3 1 0 4 4 4 0 Ig domain of plant-specific actin-binding protein MlaD PF02470.20 OIR56474.1 - 0.097 13.0 0.1 17 5.8 0.0 3.4 3 1 0 3 3 3 0 MlaD protein zf-RVT PF13966.6 OIR56475.1 - 0.0015 19.2 0.3 0.003 18.2 0.3 1.5 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase AAA_12 PF13087.6 OIR56476.1 - 3.1e-59 200.0 0.0 7.9e-59 198.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OIR56476.1 - 7.7e-51 173.4 3.9 7.6e-27 94.7 0.4 2.4 1 1 1 2 2 2 2 AAA domain UPF1_Zn_bind PF09416.10 OIR56476.1 - 3.5e-50 169.9 2.0 5.4e-50 169.3 0.7 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_30 PF13604.6 OIR56476.1 - 5.7e-17 62.1 0.6 2.2e-16 60.1 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OIR56476.1 - 2.5e-13 50.6 0.2 8.9e-13 48.8 0.1 2.0 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 OIR56476.1 - 6.8e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 OIR56476.1 - 8e-07 28.6 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.9 OIR56476.1 - 1.6e-06 27.6 2.3 0.0026 17.1 1.3 3.2 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 OIR56476.1 - 5.6e-06 26.3 0.2 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 OIR56476.1 - 9.6e-05 22.2 0.9 0.00061 19.6 0.9 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 OIR56476.1 - 0.00034 20.2 3.3 0.019 14.5 0.3 2.6 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 OIR56476.1 - 0.00061 18.8 0.2 0.0011 18.0 0.2 1.4 1 0 0 1 1 1 1 AAA-like domain Helicase_RecD PF05127.14 OIR56476.1 - 0.00068 19.5 1.1 0.0048 16.8 1.1 2.2 1 1 0 1 1 1 1 Helicase DUF5599 PF18141.1 OIR56476.1 - 0.0016 18.6 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_25 PF13481.6 OIR56476.1 - 0.0016 18.0 0.3 0.0047 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OIR56476.1 - 0.0024 17.4 0.2 0.032 13.7 0.1 2.4 2 1 0 2 2 2 1 PhoH-like protein DUF853 PF05872.12 OIR56476.1 - 0.0038 15.9 2.3 0.16 10.5 0.1 2.2 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 OIR56476.1 - 0.014 15.7 0.8 0.22 11.8 0.8 2.6 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 OIR56476.1 - 0.029 14.2 0.1 0.49 10.3 0.0 2.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 OIR56476.1 - 0.031 14.6 0.1 0.095 13.1 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Ground-like PF04155.18 OIR56476.1 - 0.04 14.6 0.1 0.094 13.4 0.1 1.5 1 0 0 1 1 1 0 Ground-like domain SRP54 PF00448.22 OIR56476.1 - 0.046 13.3 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 OIR56476.1 - 0.19 11.8 0.9 33 4.6 0.9 2.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 OIR56476.1 - 0.26 11.7 0.8 0.64 10.4 0.3 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTF2 PF02136.20 OIR56477.1 - 1.1e-17 64.7 0.0 1.2e-17 64.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OIR56477.1 - 0.00028 21.2 0.0 0.00032 21.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CHORD PF04968.12 OIR56478.1 - 0.014 16.1 2.2 0.024 15.4 2.2 1.4 1 0 0 1 1 1 0 CHORD Mor PF08765.11 OIR56480.1 - 0.024 14.6 0.0 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Mor transcription activator family zf-RVT PF13966.6 OIR56482.1 - 0.016 15.9 2.6 0.027 15.2 1.9 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56482.1 - 0.042 13.9 2.5 0.075 13.1 2.5 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain DUF2247 PF10004.9 OIR56484.1 - 0.14 11.9 1.4 0.57 9.9 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) zf-C3HC4_3 PF13920.6 OIR56485.1 - 0.011 15.6 0.7 0.02 14.7 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Unpaired PF15972.5 OIR56485.1 - 0.036 13.6 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Unpaired protein tRNA-synt_1 PF00133.22 OIR56488.1 - 1.2e-46 159.3 0.0 1.5e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OIR56488.1 - 5.7e-29 101.0 0.0 1.2e-27 96.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OIR56488.1 - 0.00013 21.5 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OIR56488.1 - 0.012 14.3 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OIR56489.1 - 9.2e-123 410.6 0.0 1e-122 410.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OIR56489.1 - 9.1e-07 27.9 0.0 7.6e-06 24.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) Reg_prop PF07494.11 OIR56490.1 - 5.4e-10 38.3 1.2 0.58 10.6 0.1 6.2 7 0 0 7 7 7 4 Two component regulator propeller MlaD PF02470.20 OIR56490.1 - 0.1 12.9 0.0 52 4.2 0.0 4.2 7 0 0 7 7 7 0 MlaD protein DUF5123 PF17161.4 OIR56494.1 - 4.3 8.4 10.9 2.1 9.4 4.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) PGM_PMM_I PF02878.16 OIR56495.1 - 6.5e-22 77.7 0.1 1.2e-21 76.8 0.1 1.4 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OIR56495.1 - 3.1e-08 34.2 0.0 7.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Macro PF01661.21 OIR56495.1 - 0.078 13.0 0.1 27 4.8 0.1 2.8 3 0 0 3 3 3 0 Macro domain Pab87_oct PF13969.6 OIR56495.1 - 0.096 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Pab87 octamerisation domain NOA36 PF06524.12 OIR56496.1 - 0.026 13.9 4.8 0.042 13.2 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein DZR PF12773.7 OIR56496.1 - 0.5 10.4 8.5 2.2 8.4 8.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OIR56496.1 - 3.7 7.4 8.2 19 5.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 OIR56496.1 - 5.5 7.2 7.3 0.46 10.7 1.3 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 OIR56496.1 - 7.5 6.1 9.9 2.5 7.6 1.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain AP-5_subunit_s1 PF15001.6 OIR56497.1 - 0.081 12.9 1.9 0.21 11.5 1.9 1.7 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 IMD PF08397.11 OIR56497.1 - 0.36 10.2 7.2 4.7 6.5 0.1 2.3 2 0 0 2 2 2 0 IRSp53/MIM homology domain GvpL_GvpF PF06386.11 OIR56497.1 - 0.51 10.2 3.3 1.8 8.4 0.9 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF241 PF03087.14 OIR56497.1 - 0.56 10.0 6.7 0.16 11.8 1.1 2.2 1 1 1 2 2 2 0 Arabidopsis protein of unknown function Ribosomal_S3_C PF00189.20 OIR56498.1 - 4.1e-23 81.7 1.8 8.4e-22 77.5 1.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OIR56498.1 - 9.6e-08 31.8 0.1 1.9e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-RVT PF13966.6 OIR56499.1 - 0.016 15.9 2.6 0.027 15.2 1.9 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56499.1 - 0.042 13.9 2.5 0.075 13.1 2.5 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain BAF250_C PF12031.8 OIR56500.1 - 3.5e-05 23.2 0.2 0.34 10.2 0.0 2.8 1 1 2 3 3 3 2 SWI/SNF-like complex subunit BAF250/Osa Reg_prop PF07494.11 OIR56500.1 - 0.00029 20.7 0.0 8 7.1 0.0 3.5 3 0 0 3 3 3 2 Two component regulator propeller TnpV PF14198.6 OIR56500.1 - 0.0047 16.9 2.0 10 6.1 0.0 4.0 4 0 0 4 4 4 2 Transposon-encoded protein TnpV Sep15_SelM PF08806.11 OIR56500.1 - 0.042 14.0 6.1 0.19 11.9 0.2 3.7 4 0 0 4 4 4 0 Sep15/SelM redox domain DUF3860 PF12976.7 OIR56500.1 - 0.078 13.0 0.6 43 4.2 0.0 3.3 3 1 1 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3860) BAF250_C PF12031.8 OIR56501.1 - 2.2e-05 23.9 1.0 0.49 9.6 0.0 4.5 2 2 2 4 4 4 1 SWI/SNF-like complex subunit BAF250/Osa zf-C3HC4_3 PF13920.6 OIR56501.1 - 3.3e-05 23.6 7.8 7.2e-05 22.6 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56501.1 - 0.00035 20.6 5.6 0.00072 19.6 5.6 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR56501.1 - 0.0097 16.1 7.3 0.041 14.1 6.9 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger Reg_prop PF07494.11 OIR56501.1 - 0.016 15.3 6.6 0.46 10.9 0.0 5.6 7 0 0 7 7 7 0 Two component regulator propeller zf-TFIIIC PF12660.7 OIR56501.1 - 0.15 12.1 0.9 0.34 10.9 0.9 1.6 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex DZR PF12773.7 OIR56501.1 - 0.27 11.3 5.6 2.3 8.3 5.9 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 OIR56501.1 - 0.4 10.7 7.6 0.86 9.6 7.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 OIR56501.1 - 0.73 9.7 8.2 6.2 6.7 8.3 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Nuc_sug_transp PF04142.15 OIR56501.1 - 0.89 8.7 3.7 4.5 6.3 0.1 3.3 3 1 1 4 4 4 0 Nucleotide-sugar transporter zf-C3HC4_4 PF15227.6 OIR56501.1 - 2.2 8.5 7.7 1.1 9.4 4.4 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OIR56501.1 - 2.2 8.4 6.2 1.6 8.8 4.1 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.12 OIR56501.1 - 5.3 7.4 7.1 2 8.8 2.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 OIR56502.1 - 4.3e-32 111.5 0.9 1.4e-31 109.8 0.9 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56502.1 - 2.8e-18 66.1 0.5 3.9e-18 65.7 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56502.1 - 4.5e-06 26.2 0.1 6.4e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OIR56502.1 - 0.0066 15.6 0.1 0.0093 15.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 OIR56502.1 - 0.0087 16.0 0.1 0.55 10.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OIR56502.1 - 0.017 14.1 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OIR56502.1 - 0.022 14.4 0.2 0.07 12.7 0.2 1.8 1 1 0 1 1 1 0 RIO1 family Phage_int_SAM_1 PF02899.17 OIR56502.1 - 0.087 13.1 0.0 4.3 7.7 0.0 2.6 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 OIR56503.1 - 1e-34 120.1 0.7 4.9e-34 117.9 1.5 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56503.1 - 6.5e-19 68.2 0.4 9.4e-19 67.7 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56503.1 - 5.1e-06 26.0 0.3 7.8e-06 25.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56503.1 - 0.002 17.7 1.3 0.0054 16.4 1.3 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 OIR56503.1 - 0.0026 17.7 0.0 0.021 14.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OIR56503.1 - 0.0099 14.9 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 OIR56503.1 - 0.021 14.4 0.1 0.038 13.6 0.1 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 OIR56504.1 - 0.026 13.9 0.0 0.93 8.8 0.0 2.0 1 1 1 2 2 2 0 Protein kinase domain zf-C3HC4_3 PF13920.6 OIR56507.1 - 1.7e-05 24.6 9.1 1.7e-05 24.6 9.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56507.1 - 0.00021 21.1 5.5 0.0007 19.4 5.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 FAM35_C PF15793.5 OIR56507.1 - 0.0034 16.8 0.6 0.0069 15.8 0.6 1.5 1 0 0 1 1 1 1 Protein family FAM35, C-terminal Acetyltransf_CG PF14542.6 OIR56507.1 - 0.019 15.1 0.4 0.042 14.0 0.4 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-RING_4 PF14570.6 OIR56507.1 - 0.02 14.6 7.3 0.02 14.6 7.3 2.4 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Reg_prop PF07494.11 OIR56507.1 - 0.027 14.7 0.1 2.8 8.5 0.0 3.3 3 0 0 3 3 3 0 Two component regulator propeller DZR PF12773.7 OIR56507.1 - 3.4 7.8 7.2 46 4.1 6.3 2.5 1 1 1 2 2 2 0 Double zinc ribbon Presenilin PF01080.17 OIR56508.1 - 8.1 5.1 5.5 11 4.7 5.5 1.2 1 0 0 1 1 1 0 Presenilin DUF1993 PF09351.10 OIR56509.1 - 0.52 10.5 3.6 0.78 9.9 0.1 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF1993) Patatin PF01734.22 OIR56511.1 - 9.2e-23 81.5 0.0 2.9e-22 79.9 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 OIR56511.1 - 0.025 14.3 0.8 0.071 12.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) zf-H2C2_2 PF13465.6 OIR56515.1 - 0.00016 22.0 1.2 0.00016 22.0 1.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 OIR56515.1 - 0.0012 19.2 16.6 0.046 14.2 3.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OIR56515.1 - 0.0044 17.6 0.2 0.0044 17.6 0.2 4.0 1 1 3 4 4 4 1 FOXP coiled-coil domain Stomagen PF16851.5 OIR56515.1 - 0.0056 16.7 0.3 0.5 10.4 0.1 2.4 2 0 0 2 2 2 1 Stomagen zf-C2H2_aberr PF17017.5 OIR56515.1 - 0.087 13.0 8.4 0.89 9.7 2.1 2.3 1 1 0 2 2 2 0 Aberrant zinc-finger CaKB PF03185.15 OIR56515.1 - 0.21 11.2 2.1 0.32 10.6 2.1 1.5 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit zf-C2H2_4 PF13894.6 OIR56515.1 - 0.37 11.8 15.5 0.2 12.6 2.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DivIC PF04977.15 OIR56515.1 - 1.9 8.3 7.1 0.88 9.4 3.3 2.3 2 0 0 2 2 2 0 Septum formation initiator TAXi_N PF14543.6 OIR56515.1 - 4.1 7.6 7.2 1.2 9.4 4.0 1.7 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal tRNA_anti-codon PF01336.25 OIR56516.1 - 0.0069 16.3 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF573 PF04504.14 OIR56523.1 - 0.0078 16.8 0.0 1.1 10.0 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF573 DUF4263 PF14082.6 OIR56523.1 - 0.035 14.4 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) DUF2536 PF10750.9 OIR56523.1 - 0.038 13.9 3.5 0.18 11.7 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) UPF0102 PF02021.17 OIR56523.1 - 0.081 13.2 0.2 0.24 11.7 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0102 Nuc_sug_transp PF04142.15 OIR56524.1 - 9.7e-05 21.7 6.1 1.4 8.0 0.0 4.9 3 2 2 5 5 5 2 Nucleotide-sugar transporter MlaD PF02470.20 OIR56524.1 - 0.0002 21.6 3.1 9.5 6.6 0.0 5.9 5 3 1 7 7 7 1 MlaD protein zf-C3HC4_3 PF13920.6 OIR56524.1 - 0.0013 18.6 6.7 0.0036 17.1 6.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TnpV PF14198.6 OIR56524.1 - 0.027 14.5 13.8 0.17 11.9 0.3 5.0 5 2 1 6 6 6 0 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR56524.1 - 0.032 14.4 1.3 1.2e+02 3.4 0.0 5.5 6 0 0 6 6 6 0 Two component regulator propeller zf-4CXXC_R1 PF10497.9 OIR56524.1 - 0.17 12.1 3.1 0.46 10.7 3.1 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_5 PF14634.6 OIR56524.1 - 0.23 11.4 3.9 1.3 9.1 4.2 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-Di19 PF05605.12 OIR56524.1 - 1 9.7 5.7 2.8 8.3 0.9 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 OIR56524.1 - 4.8 7.3 5.6 19 5.4 6.0 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 OIR56524.1 - 7.1 6.5 8.9 41 4.1 8.9 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Reg_prop PF07494.11 OIR56525.1 - 0.0028 17.7 0.0 22 5.7 0.0 3.4 3 0 0 3 3 3 1 Two component regulator propeller TnpV PF14198.6 OIR56525.1 - 0.0065 16.4 2.2 1.1 9.3 0.2 2.3 1 1 1 2 2 2 2 Transposon-encoded protein TnpV Sep15_SelM PF08806.11 OIR56525.1 - 0.013 15.7 1.5 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Sep15/SelM redox domain Unpaired PF15972.5 OIR56525.1 - 0.11 12.1 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Unpaired protein zf-C3HC4_3 PF13920.6 OIR56527.1 - 0.015 15.1 4.4 0.032 14.1 4.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pou PF00157.17 OIR56528.1 - 0.13 12.3 0.2 37 4.4 0.0 3.0 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain XAF1_C PF18608.1 OIR56528.1 - 0.42 10.2 3.2 4.3 7.0 0.5 2.8 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain DUF5383 PF17355.2 OIR56529.1 - 1.1 9.6 3.5 27 5.2 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Wbp11 PF09429.10 OIR56529.1 - 5.7 7.4 10.2 0.48 10.9 4.4 2.1 2 0 0 2 2 2 0 WW domain binding protein 11 Fibrillarin PF01269.17 OIR56531.1 - 9.9e-100 332.3 0.0 1.1e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OIR56531.1 - 5.5e-05 23.0 0.1 8.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OIR56531.1 - 0.019 14.7 0.1 0.029 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 OIR56531.1 - 0.056 13.1 0.0 0.18 11.4 0.0 1.8 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 OIR56531.1 - 0.068 13.9 0.0 0.12 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rad21_Rec8_N PF04825.13 OIR56532.1 - 4.7e-29 100.8 0.0 8.8e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OIR56532.1 - 4.4e-08 32.3 0.0 8e-07 28.3 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SNF2_N PF00176.23 OIR56533.1 - 6e-46 156.8 0.0 1.6e-45 155.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OIR56533.1 - 3.8e-11 43.3 0.0 7.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR56533.1 - 0.00075 19.5 0.0 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OIR56533.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase PET PF06297.14 OIR56534.1 - 0.0017 18.6 0.2 0.14 12.5 0.0 2.3 2 0 0 2 2 2 2 PET Domain TRAP-gamma PF07074.12 OIR56534.1 - 1.1 8.8 8.8 0.85 9.2 5.4 2.0 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) SYCP2_SLD PF18584.1 OIR56538.1 - 0.025 14.8 3.9 0.14 12.4 0.6 2.7 2 0 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain Imm-NTF2 PF15655.6 OIR56538.1 - 2.1 8.6 5.6 4.4 7.6 1.0 3.1 3 0 0 3 3 3 0 NTF2 fold immunity protein NLRC4_HD2 PF17776.1 OIR56539.1 - 0.1 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 NLRC4 helical domain HD2 PI3_PI4_kinase PF00454.27 OIR56539.1 - 0.13 12.0 0.0 0.47 10.2 0.0 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Diphthamide_syn PF01866.17 OIR56540.1 - 3e-07 30.2 0.0 3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Myb_DNA-binding PF00249.31 OIR56542.1 - 2e-10 40.7 1.5 2.5e-07 30.8 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR56542.1 - 8.4e-07 29.1 8.3 0.00017 21.8 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Carb_kinase PF01256.17 OIR56543.1 - 1e-42 146.3 0.0 1.2e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OIR56543.1 - 0.00058 19.3 0.0 0.0015 18.0 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase rve PF00665.26 OIR56545.1 - 1.3e-21 77.0 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR56545.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_IS240 PF13610.6 OIR56545.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 DDE domain FHA_2 PF17913.1 OIR56547.1 - 0.0043 17.3 0.5 2.2 8.5 0.1 3.2 1 1 2 3 3 3 2 FHA domain DUF1086 PF06461.11 OIR56548.1 - 0.091 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) RWP-RK PF02042.15 OIR56549.1 - 4e-05 23.5 23.7 0.41 10.7 0.2 5.7 2 2 4 6 6 6 2 RWP-RK domain HTH_6 PF01418.17 OIR56549.1 - 5.9e-05 23.0 7.2 0.075 13.0 1.0 3.3 2 1 1 3 3 3 2 Helix-turn-helix domain, rpiR family OmpH PF03938.14 OIR56549.1 - 0.00047 20.5 33.2 0.15 12.4 7.6 3.0 1 1 1 2 2 2 2 Outer membrane protein (OmpH-like) HrpB7 PF09486.10 OIR56549.1 - 0.0082 16.5 0.8 0.0082 16.5 0.8 2.8 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB7) V-SNARE_C PF12352.8 OIR56549.1 - 0.014 15.6 21.3 0.085 13.2 2.5 4.1 3 1 1 5 5 4 0 Snare region anchored in the vesicle membrane C-terminus DHR10 PF18595.1 OIR56549.1 - 0.027 14.5 26.6 0.11 12.5 4.5 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Vps5 PF09325.10 OIR56549.1 - 0.05 13.1 23.1 0.26 10.8 3.0 2.1 1 1 1 2 2 2 0 Vps5 C terminal like COG2 PF06148.11 OIR56549.1 - 0.091 12.8 14.0 1.7 8.7 1.0 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mga PF05043.13 OIR56549.1 - 0.18 12.4 10.7 4 8.1 0.1 3.5 2 1 1 3 3 3 0 Mga helix-turn-helix domain Spc7 PF08317.11 OIR56549.1 - 0.21 10.4 27.4 0.25 10.2 18.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 OIR56549.1 - 0.21 11.3 19.9 0.061 13.0 11.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) BLOC1S3 PF15753.5 OIR56549.1 - 0.32 11.1 13.5 5.9 7.0 7.5 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Syntaxin-6_N PF09177.11 OIR56549.1 - 0.45 11.1 21.4 0.21 12.2 13.0 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DASH_Duo1 PF08651.10 OIR56549.1 - 0.52 10.1 16.9 1.1 9.0 2.2 3.6 2 1 2 4 4 4 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 OIR56549.1 - 0.57 10.7 15.8 0.25 11.8 4.9 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TBCA PF02970.16 OIR56549.1 - 0.66 10.3 17.4 0.07 13.5 9.9 2.5 1 1 0 2 2 2 0 Tubulin binding cofactor A KxDL PF10241.9 OIR56549.1 - 0.67 10.3 29.0 0.58 10.5 13.9 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein WXG100 PF06013.12 OIR56549.1 - 0.73 10.1 13.7 15 5.9 0.2 3.4 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Sec8_exocyst PF04048.14 OIR56549.1 - 0.91 9.4 24.0 0.62 10.0 2.3 3.1 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Exonuc_VII_L PF02601.15 OIR56549.1 - 1.2 8.6 28.9 0.98 8.9 16.2 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF1822 PF08852.11 OIR56549.1 - 1.2 8.0 20.8 1.7 7.6 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Flagellin_N PF00669.20 OIR56549.1 - 2.2 8.4 19.1 14 5.8 0.3 3.2 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region RT_RNaseH_2 PF17919.1 OIR56549.1 - 2.3 8.3 9.6 8.7 6.4 0.9 3.2 2 1 1 3 3 3 0 RNase H-like domain found in reverse transcriptase LKAAEAR PF15478.6 OIR56549.1 - 2.6 8.3 20.5 2 8.7 9.3 2.2 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif Stn1 PF10451.9 OIR56549.1 - 2.6 6.9 12.3 3.3 6.6 8.6 2.1 1 1 1 2 2 2 0 Telomere regulation protein Stn1 DUF3552 PF12072.8 OIR56549.1 - 3.5 7.0 26.8 0.76 9.2 15.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) FapA PF03961.13 OIR56549.1 - 3.6 6.1 21.9 0.15 10.6 12.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CLZ PF16526.5 OIR56549.1 - 3.7 8.0 27.9 2.9 8.3 6.7 3.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMPIT PF07851.13 OIR56549.1 - 4.1 6.6 26.0 0.25 10.5 14.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein Com_YlbF PF06133.11 OIR56549.1 - 4.7 7.9 18.7 5.5e+03 -2.0 18.7 2.9 1 1 0 1 1 0 0 Control of competence regulator ComK, YlbF/YmcA HisKA_3 PF07730.13 OIR56549.1 - 5.1 7.7 7.1 18 5.9 3.1 3.1 1 1 1 2 2 2 0 Histidine kinase DUF1664 PF07889.12 OIR56549.1 - 5.9 6.9 15.0 4 7.5 5.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) sCache_like PF16736.5 OIR56549.1 - 6.1 7.0 10.7 17 5.6 5.8 2.9 2 1 1 3 3 3 0 Single Cache-like GAT PF03127.14 OIR56549.1 - 8.1 6.8 16.4 16 5.9 0.8 3.7 1 1 2 3 3 3 0 GAT domain E2R135 PF11570.8 OIR56549.1 - 8.2 6.7 13.0 24 5.2 1.2 3.4 2 1 1 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 PCRF PF03462.18 OIR56549.1 - 8.3 6.2 17.4 2.1 8.1 7.1 2.2 1 1 1 2 2 2 0 PCRF domain DUF16 PF01519.16 OIR56549.1 - 8.5 6.9 19.6 2.9 8.4 11.1 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 ATG16 PF08614.11 OIR56549.1 - 9.6 6.4 34.2 3.5e+02 1.3 34.2 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PHM7_ext PF12621.8 OIR56550.1 - 5.6e-06 26.4 0.2 13 6.0 0.0 6.2 6 0 0 6 6 6 1 Extracellular tail, of 10TM putative phosphate transporter Reg_prop PF07494.11 OIR56550.1 - 0.00073 19.5 1.0 49 4.7 0.0 6.9 8 0 0 8 8 8 0 Two component regulator propeller DUF3060 PF11259.8 OIR56550.1 - 0.001 18.7 0.3 5.6 6.7 0.0 5.3 6 0 0 6 6 6 1 Protein of unknown function (DUF3060) YcxB PF14317.6 OIR56550.1 - 0.0081 15.8 0.0 14 5.5 0.0 5.0 7 0 0 7 7 7 1 YcxB-like protein MqsR_toxin PF15723.5 OIR56550.1 - 0.06 13.7 11.6 27 5.2 0.1 7.0 3 2 5 8 8 8 0 Motility quorum-sensing regulator, toxin of MqsA Aldo_ket_red PF00248.21 OIR56550.1 - 0.085 12.0 8.1 2.3 7.4 0.1 4.8 2 1 2 6 6 6 0 Aldo/keto reductase family DUF1323 PF07037.11 OIR56550.1 - 0.11 12.9 24.4 13 6.1 0.2 6.4 5 2 1 6 6 6 0 Putative transcription regulator (DUF1323) zf-C3HC4_3 PF13920.6 OIR56550.1 - 0.56 10.1 8.0 1.1 9.2 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RabGGT_insert PF07711.11 OIR56550.1 - 0.79 10.2 6.1 2.2e+02 2.4 0.0 6.4 4 4 4 8 8 8 0 Rab geranylgeranyl transferase alpha-subunit, insert domain TFIID_20kDa PF03847.13 OIR56550.1 - 4.9 7.7 7.7 38 4.9 0.1 4.4 4 0 0 4 4 4 0 Transcription initiation factor TFIID subunit A DUF2842 PF11003.8 OIR56552.1 - 0.072 13.4 1.5 0.08 13.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) DUF1726 PF08351.11 OIR56553.1 - 0.19 11.7 1.0 3.6 7.6 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1726) zf-C3HC4_3 PF13920.6 OIR56554.1 - 0.013 15.4 6.6 0.026 14.4 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.13 OIR56554.1 - 0.048 11.5 2.5 0.051 11.5 2.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Anti-TRAP PF15777.5 OIR56554.1 - 0.27 11.2 6.1 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-XS PF03470.14 OIR56554.1 - 2.7 8.3 4.6 12 6.2 0.1 2.4 2 0 0 2 2 2 0 XS zinc finger domain HypA PF01155.19 OIR56554.1 - 6.6 6.8 8.9 0.85 9.7 0.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4451 PF14616.6 OIR56554.1 - 7.7 6.7 7.7 28 4.9 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Nucleic_acid_bd PF13820.6 OIR56555.1 - 0.038 13.8 6.0 12 5.7 0.0 5.1 6 0 0 6 6 6 0 Putative nucleic acid-binding region MlaD PF02470.20 OIR56555.1 - 0.058 13.7 0.0 14 6.1 0.0 4.2 4 1 1 5 5 5 0 MlaD protein DUF2714 PF10896.8 OIR56555.1 - 0.096 12.7 0.2 7.4 6.6 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2714) zf-UDP PF14569.6 OIR56555.1 - 0.76 9.9 4.6 2.4 8.3 4.6 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Reg_prop PF07494.11 OIR56555.1 - 0.96 9.9 3.1 2.6e+02 2.5 0.0 5.3 7 1 0 7 7 7 0 Two component regulator propeller zf-C3HC4_3 PF13920.6 OIR56555.1 - 0.98 9.3 9.9 0.46 10.4 6.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ANAPC15 PF15243.6 OIR56555.1 - 2.5 8.5 7.9 52 4.3 0.1 4.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 15 BAF250_C PF12031.8 OIR56556.1 - 1.8e-05 24.2 0.0 0.00026 20.4 0.0 2.4 1 1 1 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa Reg_prop PF07494.11 OIR56556.1 - 2.9e-05 23.8 0.1 12 6.5 0.0 4.1 4 0 0 4 4 4 3 Two component regulator propeller Unpaired PF15972.5 OIR56556.1 - 0.0038 16.8 3.2 2.5 7.6 0.1 3.0 1 1 2 3 3 3 2 Unpaired protein DUF1419 PF07215.11 OIR56556.1 - 0.012 15.7 0.0 0.83 9.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1419) Lectin_C PF00059.21 OIR56556.1 - 0.16 12.7 0.8 2.6e+02 2.4 0.0 3.8 4 0 0 4 4 4 0 Lectin C-type domain Nucleic_acid_bd PF13820.6 OIR56556.1 - 0.36 10.7 7.7 10 6.0 0.1 3.8 4 0 0 4 4 4 0 Putative nucleic acid-binding region Fox-1_C PF12414.8 OIR56557.1 - 0.027 14.8 0.1 0.067 13.6 0.1 1.6 1 1 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal TCRP1 PF14944.6 OIR56557.1 - 0.041 13.8 0.1 0.057 13.4 0.1 1.2 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 zf-RVT PF13966.6 OIR56558.1 - 0.009 16.7 1.9 0.025 15.3 1.9 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56558.1 - 0.039 14.0 2.5 0.069 13.2 2.5 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain DUF4857 PF16149.5 OIR56559.1 - 0.22 10.7 0.2 0.36 10.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4857) Ribosomal_L27 PF01016.19 OIR56559.1 - 3.1 7.9 17.2 1.1 9.3 2.6 3.8 1 1 3 4 4 4 0 Ribosomal L27 protein zf-RVT PF13966.6 OIR56560.1 - 0.016 15.9 2.6 0.027 15.2 1.9 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56560.1 - 0.042 13.9 2.5 0.075 13.1 2.5 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain zf-RVT PF13966.6 OIR56561.1 - 0.016 15.9 2.6 0.027 15.2 1.9 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56561.1 - 0.042 13.9 2.5 0.075 13.1 2.5 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain tRNA_synt_1c_R1 PF04558.15 OIR56562.1 - 8.8e-30 103.8 4.5 1.2e-29 103.4 4.5 1.2 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 ADSL_C PF10397.9 OIR56562.1 - 0.01 16.4 1.0 0.28 11.8 0.3 2.5 2 1 1 3 3 3 0 Adenylosuccinate lyase C-terminus tRNA_synt_1c_R2 PF04557.15 OIR56562.1 - 0.026 15.5 0.3 0.026 15.5 0.3 2.6 2 1 1 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Pyr_redox PF00070.27 OIR56562.1 - 0.037 14.6 0.3 0.11 13.1 0.2 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PP2C_C PF07830.13 OIR56562.1 - 2.8 8.5 5.1 3.3 8.2 0.5 2.8 1 1 2 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain GSHPx PF00255.19 OIR56564.1 - 6.5e-29 99.7 0.0 8.1e-29 99.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 OIR56564.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OIR56564.1 - 0.0036 17.0 0.0 0.021 14.6 0.0 1.9 1 1 0 1 1 1 1 Redoxin TPR_1 PF00515.28 OIR56565.1 - 5.9e-15 54.4 8.8 2.2e-05 24.1 0.5 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OIR56565.1 - 2e-11 43.1 7.2 0.0011 18.9 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OIR56565.1 - 3.9e-10 39.1 5.0 0.00012 22.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OIR56565.1 - 3.1e-09 37.2 0.6 8.6e-07 29.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OIR56565.1 - 1.1e-08 34.5 1.1 0.0071 16.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 OIR56565.1 - 1.8e-07 31.3 1.0 2.2e-05 24.7 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OIR56565.1 - 4.2e-07 30.3 0.3 0.0012 19.5 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OIR56565.1 - 9.8e-07 28.7 1.3 0.068 13.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OIR56565.1 - 1.6e-06 27.7 5.6 0.0017 18.0 0.8 3.3 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 OIR56565.1 - 2.6e-05 24.8 1.2 0.41 11.3 0.0 3.7 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OIR56565.1 - 0.0024 18.4 3.7 0.025 15.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 OIR56565.1 - 0.0032 16.7 0.1 0.75 9.0 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OIR56565.1 - 0.014 15.6 0.1 0.034 14.3 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 OIR56565.1 - 0.022 14.6 3.3 5 7.1 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DER1 PF04511.15 OIR56566.1 - 4.4e-34 118.1 0.8 5.1e-34 117.9 0.8 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 OIR56566.1 - 0.00043 20.3 0.4 0.0013 18.8 0.4 1.8 1 1 0 1 1 1 1 Rhomboid family LsmAD PF06741.13 OIR56567.1 - 8.8e-08 32.6 1.7 8.8e-08 32.6 1.7 1.7 2 0 0 2 2 2 1 LsmAD domain Act-Frag_cataly PF09192.10 OIR56567.1 - 0.0037 16.7 0.1 0.0045 16.4 0.1 1.0 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic MtrG PF04210.13 OIR56567.1 - 1.8 8.5 3.3 3.7 7.5 1.3 2.0 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4337 PF14235.6 OIR56567.1 - 3.2 7.9 4.3 4.3 7.4 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) zf-C3HC4_3 PF13920.6 OIR56568.1 - 5.5e-06 26.1 5.3 1.4e-05 24.9 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MlaD PF02470.20 OIR56568.1 - 0.00034 20.9 0.2 11 6.4 0.0 5.8 6 2 1 8 8 8 1 MlaD protein GcrA PF07750.11 OIR56568.1 - 0.0012 19.3 0.9 8.1 6.8 0.0 4.6 4 1 1 5 5 5 1 GcrA cell cycle regulator Guanylin PF02058.15 OIR56568.1 - 0.078 13.5 1.6 8 7.0 0.0 3.1 2 0 0 2 2 2 0 Guanylin precursor Reg_prop PF07494.11 OIR56568.1 - 0.15 12.4 0.5 44 4.8 0.0 3.7 3 0 0 3 3 3 0 Two component regulator propeller Biotin_lipoyl PF00364.22 OIR56568.1 - 0.66 9.9 6.6 19 5.2 0.0 4.2 5 0 0 5 5 5 0 Biotin-requiring enzyme DUF3860 PF12976.7 OIR56568.1 - 0.99 9.5 3.1 64 3.7 0.0 5.0 7 1 1 8 8 8 0 Domain of Unknown Function with PDB structure (DUF3860) zf-RING_4 PF14570.6 OIR56568.1 - 1.5 8.7 7.0 3.2 7.6 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OIR56568.1 - 1.7 8.8 5.6 4 7.6 5.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 OIR56569.1 - 0.0018 18.1 6.4 0.0026 17.6 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56569.1 - 0.018 15.1 3.5 0.049 13.7 3.5 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Di19 PF05605.12 OIR56569.1 - 0.12 12.7 4.9 0.3 11.4 0.1 2.7 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 OIR56569.1 - 0.35 10.8 5.9 3.3 7.7 5.9 2.4 1 1 0 1 1 1 0 PHD-finger DUF4451 PF14616.6 OIR56569.1 - 3.2 8.0 8.0 0.54 10.5 0.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-RING_5 PF14634.6 OIR56569.1 - 5.2 7.1 7.9 5.1 7.1 5.1 2.4 2 1 1 3 3 3 0 zinc-RING finger domain DNA_PPF PF02916.15 OIR56570.1 - 7.3e-08 32.8 21.1 3.2 8.2 0.0 8.5 4 2 5 9 9 9 4 DNA polymerase processivity factor DUF5023 PF16426.5 OIR56570.1 - 0.00017 21.4 0.1 1.3 8.6 0.0 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF5023) zf-UDP PF14569.6 OIR56570.1 - 0.069 13.3 4.3 0.15 12.2 4.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 OIR56570.1 - 0.082 12.8 5.2 0.17 11.8 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56570.1 - 0.14 12.0 5.9 0.55 10.1 5.9 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PIN_2 PF10130.9 OIR56570.1 - 0.44 10.8 17.6 2.1 8.6 0.3 5.2 3 1 1 5 5 5 0 PIN domain FYVE_2 PF02318.16 OIR56570.1 - 0.58 10.4 6.8 0.34 11.1 1.7 3.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 OIR56570.1 - 1.8 8.6 6.0 5.3 7.1 6.0 1.9 1 1 0 1 1 1 0 zinc-RING finger domain RT_RNaseH PF17917.1 OIR56572.1 - 4.9e-37 126.4 0.0 1.5e-36 124.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OIR56572.1 - 1.9e-32 111.3 0.0 7e-32 109.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OIR56572.1 - 7.7e-32 110.6 0.1 2e-31 109.2 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OIR56572.1 - 1.7e-27 96.0 0.0 1.7e-26 92.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 OIR56572.1 - 2.5e-11 44.0 0.1 8.1e-11 42.3 0.1 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56572.1 - 8.2e-10 39.2 0.1 3e-09 37.4 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 OIR56572.1 - 1.5e-05 25.0 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OIR56572.1 - 0.001 18.8 0.0 0.003 17.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.20 OIR56572.1 - 0.0024 18.1 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 OIR56572.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 OIR56572.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2_10 PF16588.5 OIR56572.1 - 0.18 11.6 6.4 0.036 13.8 2.6 1.9 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 OIR56572.1 - 0.35 11.0 1.5 0.84 9.8 1.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Hydrolase PF00702.26 OIR56573.1 - 1.4e-08 35.3 0.0 0.0047 17.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OIR56573.1 - 0.19 11.5 0.5 11 5.6 0.0 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase YdjM PF04307.14 OIR56573.1 - 0.31 10.3 3.8 0.11 11.8 0.3 1.8 2 1 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Vg_Tdu PF07545.14 OIR56574.1 - 0.043 13.6 0.0 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Vestigial/Tondu family DUF1283 PF06932.11 OIR56574.1 - 0.063 13.5 0.0 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) RT_RNaseH PF17917.1 OIR56575.1 - 1.1e-37 128.5 0.0 2.2e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OIR56575.1 - 2.5e-35 120.5 0.0 6.4e-35 119.2 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OIR56575.1 - 1.9e-33 115.9 0.0 3.5e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 OIR56575.1 - 1.5e-05 25.5 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OIR56575.1 - 0.00056 20.2 0.0 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OIR56575.1 - 0.095 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DnaJ PF00226.31 OIR56576.1 - 2.1e-10 40.6 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.31 OIR56577.1 - 1.2e-27 95.8 5.5 1.9e-27 95.1 5.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 OIR56577.1 - 9.9e-26 90.6 0.1 1.4e-25 90.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain RPT PF13446.6 OIR56577.1 - 0.0012 18.8 0.0 0.0033 17.3 0.0 1.7 1 1 0 1 1 1 1 A repeated domain in UCH-protein DUF150_C PF17384.2 OIR56577.1 - 0.1 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Pkinase PF00069.25 OIR56578.1 - 1.7e-38 132.5 0.0 2.8e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56578.1 - 1.7e-14 53.8 0.0 6.7e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OIR56578.1 - 0.0066 15.3 0.3 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 OIR56578.1 - 0.035 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Brr6_like_C_C PF10104.9 OIR56579.1 - 3e-44 150.0 0.2 3.9e-44 149.6 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4087 PF13316.6 OIR56580.1 - 0.061 13.8 0.2 0.075 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) RVT_1 PF00078.27 OIR56581.1 - 8.2e-11 41.8 0.0 8.3e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F420H2_quin_red PF04075.14 OIR56581.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase zf-C3HC4_3 PF13920.6 OIR56584.1 - 0.0029 17.4 3.2 0.0073 16.1 3.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FHA_2 PF17913.1 OIR56584.1 - 0.011 15.9 0.0 1.1e+02 3.1 0.0 5.4 5 1 0 5 5 5 0 FHA domain NO_synthase PF02898.15 OIR56584.1 - 0.086 11.9 0.3 13 4.6 0.0 4.1 3 1 3 6 6 6 0 Nitric oxide synthase, oxygenase domain zf-P11 PF03854.14 OIR56584.1 - 0.79 9.4 5.1 3 7.6 5.1 2.0 1 0 0 1 1 1 0 P-11 zinc finger Prok-RING_1 PF14446.6 OIR56584.1 - 4.2 7.4 6.7 2.9 7.9 1.8 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 SpoIID PF08486.10 OIR56584.1 - 7.3 7.2 5.7 41 4.8 0.0 4.4 6 0 0 6 6 6 0 Stage II sporulation protein Mitofilin PF09731.9 OIR56585.1 - 1.9 7.2 28.0 2.5 6.8 28.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RVT_1 PF00078.27 OIR56586.1 - 9.8e-42 143.0 0.0 1.9e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OIR56586.1 - 0.0021 17.6 0.0 0.0075 15.8 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR56586.1 - 0.018 14.8 0.3 0.16 11.8 0.1 2.7 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase GCIP PF13324.6 OIR56587.1 - 0.19 11.3 3.1 0.27 10.8 3.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 OIR56587.1 - 0.4 10.4 9.3 0.62 9.8 9.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 OIR56587.1 - 0.43 10.6 3.5 0.84 9.6 3.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 OIR56587.1 - 0.55 9.5 14.1 0.78 9.0 14.1 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OIR56587.1 - 0.58 9.8 2.8 0.98 9.1 2.8 1.4 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 OIR56587.1 - 4.3 5.4 11.6 5.5 5.1 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4248 PF14053.6 OIR56588.1 - 0.034 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Exo_endo_phos_2 PF14529.6 OIR56588.1 - 0.039 13.8 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase OAD_gamma PF04277.13 OIR56589.1 - 0.097 13.3 0.1 0.31 11.7 0.1 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain HIT PF01230.23 OIR56590.1 - 1.7e-19 70.4 0.1 2.3e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OIR56590.1 - 3.4e-11 43.6 0.0 5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OIR56590.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 WD40 PF00400.32 OIR56591.1 - 0.11 13.4 4.3 0.18 12.7 0.0 3.4 4 1 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR56591.1 - 0.15 12.4 0.0 1.1 9.6 0.0 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RT_RNaseH PF17917.1 OIR56592.1 - 1.3e-33 115.4 0.0 2.4e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OIR56592.1 - 1.2e-32 113.3 0.1 1.9e-32 112.6 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OIR56592.1 - 7.1e-29 99.8 0.0 1.8e-28 98.5 0.0 1.7 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OIR56592.1 - 3.1e-19 69.3 0.0 1.3e-18 67.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.6 OIR56592.1 - 2.8e-10 40.6 0.0 6.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56592.1 - 2e-09 38.0 0.0 4.3e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OIR56592.1 - 8.8e-09 35.2 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 OIR56592.1 - 1.6e-06 28.1 0.0 4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease PF09668.10 OIR56592.1 - 1.4e-05 24.9 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease MLVIN_C PF18697.1 OIR56592.1 - 0.0048 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DDE_3 PF13358.6 OIR56592.1 - 0.0072 16.1 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease gag_pre-integrs PF13976.6 OIR56592.1 - 0.013 15.4 0.1 0.046 13.6 0.0 2.0 2 0 0 2 2 2 0 GAG-pre-integrase domain Peptidase_A2E PF12382.8 OIR56592.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon peptidase DUF1758 PF05585.12 OIR56592.1 - 0.02 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Peptidase_A2B PF12384.8 OIR56592.1 - 0.044 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase rve_3 PF13683.6 OIR56592.1 - 0.051 13.4 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain zf-H2C2 PF09337.10 OIR56592.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve PF00665.26 OIR56593.1 - 3.9e-06 27.0 0.0 1.5e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 Integrase core domain Pkinase PF00069.25 OIR56595.1 - 1.2e-28 100.2 0.0 2.6e-28 99.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56595.1 - 1.5e-16 60.5 0.0 2.9e-16 59.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56595.1 - 5e-07 29.3 0.1 1.2e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR56595.1 - 0.00026 20.7 0.0 0.61 9.7 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OIR56595.1 - 0.00044 19.3 0.1 0.00059 18.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56595.1 - 0.00071 19.6 0.1 0.014 15.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OIR56595.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.7 1 1 0 1 1 1 0 RIO1 family DUF4096 PF13340.6 OIR56595.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Pkinase PF00069.25 OIR56596.1 - 2.7e-28 99.1 0.1 3.4e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56596.1 - 6.7e-17 61.6 0.0 1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56596.1 - 3.1e-07 30.0 0.1 5.1e-07 29.3 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR56596.1 - 0.035 14.0 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR56596.1 - 0.063 12.6 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 OIR56596.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 OIR56598.1 - 1.3e-30 106.7 0.2 2.3e-30 105.8 0.1 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56598.1 - 6.5e-17 61.7 0.0 9.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56598.1 - 2.2e-08 33.7 0.7 4.8e-08 32.6 0.7 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR56598.1 - 4.3e-05 23.2 0.1 0.025 14.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OIR56598.1 - 0.00069 18.7 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56598.1 - 0.04 13.8 0.1 0.16 11.9 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OIR56598.1 - 0.088 12.4 0.2 0.23 11.0 0.1 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Sulfatase PF00884.23 OIR56599.1 - 3.3e-24 85.9 0.0 4.3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OIR56599.1 - 6.1e-05 21.8 0.0 8.6e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 OIR56599.1 - 0.048 13.2 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase z-alpha PF02295.17 OIR56599.1 - 0.099 12.7 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain DUF3253 PF11625.8 OIR56604.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) RVT_1 PF00078.27 OIR56606.1 - 6.7e-44 150.0 0.0 1e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 OIR56606.1 - 0.0026 18.4 2.1 0.0082 16.8 0.5 2.4 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF3545 PF12065.8 OIR56606.1 - 0.065 13.3 3.9 0.091 12.8 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Allantoicase PF03561.15 OIR56607.1 - 0.039 13.9 0.2 0.06 13.3 0.1 1.3 1 1 0 1 1 1 0 Allantoicase repeat YqfQ PF14181.6 OIR56607.1 - 0.086 13.0 1.6 0.1 12.8 1.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_S77 PF03420.13 OIR56607.1 - 0.092 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Prohead core protein serine protease QSregVF PF13652.6 OIR56607.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Imm51 PF15595.6 OIR56609.1 - 0.012 15.5 0.6 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 51 DUF4833 PF16117.5 OIR56611.1 - 0.0031 17.5 0.1 78 3.3 0.0 5.4 5 1 0 6 6 6 0 Domain of unknown function (DUF4833) zf-C3HC4_3 PF13920.6 OIR56611.1 - 0.0089 15.9 11.1 0.017 15.0 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OIR56611.1 - 0.0098 16.0 9.9 1.2e+02 3.4 0.0 8.2 12 0 0 12 12 12 0 Two component regulator propeller zf-UDP PF14569.6 OIR56611.1 - 0.23 11.6 7.7 0.54 10.4 7.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR56611.1 - 0.25 11.5 7.2 1.2 9.4 7.2 2.2 1 0 0 1 1 1 0 FYVE-type zinc finger Nucleic_acid_bd PF13820.6 OIR56611.1 - 0.4 10.5 19.5 16 5.4 0.3 8.1 8 2 2 10 10 10 0 Putative nucleic acid-binding region zf-RING_4 PF14570.6 OIR56611.1 - 4.1 7.3 10.7 25 4.7 10.7 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain HypA PF01155.19 OIR56611.1 - 6.1 6.9 8.4 29 4.7 8.4 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sep15_SelM PF08806.11 OIR56612.1 - 0.032 14.4 0.3 0.49 10.6 0.0 2.8 3 0 0 3 3 3 0 Sep15/SelM redox domain Reg_prop PF07494.11 OIR56612.1 - 0.067 13.4 2.1 26 5.5 0.0 4.3 4 0 0 4 4 4 0 Two component regulator propeller Sep15_SelM PF08806.11 OIR56613.1 - 5.3e-06 26.5 4.6 0.92 9.7 0.0 5.0 5 0 0 5 5 5 2 Sep15/SelM redox domain MlaD PF02470.20 OIR56614.1 - 0.055 13.8 0.0 8.9 6.7 0.0 3.1 3 0 0 3 3 3 0 MlaD protein MciZ PF13072.6 OIR56614.1 - 0.056 13.3 0.3 0.37 10.6 0.1 2.5 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ zf-C3HC4_3 PF13920.6 OIR56615.1 - 4e-05 23.4 5.5 7.9e-05 22.4 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2110 PF09883.9 OIR56615.1 - 0.012 15.2 2.7 1.7 8.2 0.2 5.0 4 2 2 6 6 6 0 Uncharacterized protein conserved in archaea (DUF2110) Reg_prop PF07494.11 OIR56615.1 - 0.017 15.2 13.6 0.47 10.9 0.1 6.3 6 1 0 6 6 5 0 Two component regulator propeller zf-RING_2 PF13639.6 OIR56615.1 - 0.024 15.0 7.1 0.075 13.4 7.1 1.9 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 OIR56615.1 - 0.044 13.9 5.3 0.11 12.6 5.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DCP1 PF06058.13 OIR56615.1 - 0.087 12.8 0.0 1.8 8.5 0.0 2.7 1 1 1 2 2 2 0 Dcp1-like decapping family TarS_C1 PF18674.1 OIR56615.1 - 0.097 12.6 0.2 1e+02 2.8 0.0 3.9 4 0 0 4 4 4 0 TarS beta-glycosyltransferase C-terminal domain 1 zf-RING_5 PF14634.6 OIR56615.1 - 0.16 11.9 6.4 0.37 10.8 6.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-BED PF02892.15 OIR56615.1 - 0.43 10.6 2.3 17 5.5 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 OIR56615.1 - 1.5 9.1 6.7 5.6 7.3 3.0 2.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 OIR56615.1 - 2.6 7.9 7.7 6.1 6.7 7.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Exo_endo_phos PF03372.23 OIR56622.1 - 0.0021 17.6 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cob_adeno_trans PF01923.18 OIR56623.1 - 0.029 14.5 0.1 0.033 14.3 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase dCache_2 PF08269.11 OIR56623.1 - 0.029 13.6 0.5 0.034 13.3 0.5 1.1 1 0 0 1 1 1 0 Cache domain Baculo_DNA_bind PF04786.12 OIR56624.1 - 0.035 13.5 0.4 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 ssDNA binding protein zf-UDP PF14569.6 OIR56627.1 - 0.014 15.5 5.9 0.036 14.2 5.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger HypA PF01155.19 OIR56627.1 - 4 7.5 8.5 0.64 10.1 4.2 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 OIR56628.1 - 0.006 16.4 4.7 0.018 14.9 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56628.1 - 0.089 12.9 2.7 0.22 11.7 2.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF1297 PF06973.12 OIR56629.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) ACT_5 PF13710.6 OIR56630.1 - 0.17 11.7 0.7 22 5.0 0.0 3.0 3 0 0 3 3 3 0 ACT domain PGM_PMM_III PF02880.16 OIR56631.1 - 0.079 13.2 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Lipid_DES PF08557.10 OIR56631.1 - 0.32 10.5 1.2 4.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Sphingolipid Delta4-desaturase (DES) CSTF_C PF14304.6 OIR56632.1 - 0.029 14.0 0.3 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal PARG_cat PF05028.14 OIR56632.1 - 0.078 12.2 0.1 0.083 12.2 0.1 1.1 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Exo_endo_phos PF03372.23 OIR56633.1 - 6.1e-08 32.5 0.0 6.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C3HC4_3 PF13920.6 OIR56637.1 - 0.00097 18.9 6.6 0.0021 17.9 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sep15_SelM PF08806.11 OIR56637.1 - 0.32 11.2 3.4 4.7 7.4 0.0 3.5 4 0 0 4 4 4 0 Sep15/SelM redox domain DHHA1 PF02272.19 OIR56641.1 - 0.095 13.1 0.2 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 DHHA1 domain UDG PF03167.19 OIR56646.1 - 7.5e-22 78.0 0.0 1e-21 77.5 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_L37ae PF01780.19 OIR56647.1 - 5.1e-38 129.0 9.4 5.7e-38 128.9 9.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Lar_restr_allev PF14354.6 OIR56647.1 - 0.0043 17.4 0.2 0.0061 16.9 0.2 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 OIR56647.1 - 0.0068 16.3 2.5 0.013 15.5 2.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain C1_2 PF03107.16 OIR56647.1 - 0.012 15.9 0.5 0.018 15.4 0.5 1.2 1 0 0 1 1 1 0 C1 domain Rep_fac-A_C PF08646.10 OIR56647.1 - 0.035 13.9 0.4 0.039 13.7 0.4 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain ZZ PF00569.17 OIR56647.1 - 0.045 13.6 4.1 0.086 12.7 4.1 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type OrfB_Zn_ribbon PF07282.11 OIR56647.1 - 0.07 13.1 2.9 0.096 12.6 2.8 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 OIR56647.1 - 0.14 11.8 0.6 16 5.2 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger YyzF PF14116.6 OIR56647.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.7 2 0 0 2 2 2 0 YyzF-like protein NIF PF03031.18 OIR56648.1 - 9.8e-14 51.4 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DPM3 PF08285.11 OIR56649.1 - 7.2e-10 38.9 1.2 8.4e-10 38.7 1.2 1.1 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2207 PF09972.9 OIR56649.1 - 0.23 10.2 2.0 0.3 9.8 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MCM_bind PF09739.9 OIR56650.1 - 2.2e-23 82.6 0.0 3.3e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor RhoGAP PF00620.27 OIR56651.1 - 5e-29 101.1 0.1 1.6e-28 99.4 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain zf-C3HC4_3 PF13920.6 OIR56652.1 - 0.006 16.4 3.2 0.006 16.4 3.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 OIR56652.1 - 0.1 13.1 15.2 0.17 12.3 6.1 3.9 2 2 1 3 3 3 0 RING/Ubox like zinc-binding domain PMM PF03332.13 OIR56654.1 - 3.1e-99 331.2 1.6 3.6e-99 331.0 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OIR56654.1 - 2e-05 24.5 0.0 0.00015 21.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OIR56654.1 - 0.0032 17.0 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 OIR56654.1 - 0.012 15.9 0.1 0.045 14.0 0.1 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase GAS PF13851.6 OIR56655.1 - 4.4 6.6 41.3 13 5.1 21.2 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Glycos_transf_2 PF00535.26 OIR56658.1 - 3.1e-24 85.7 0.2 3.6e-24 85.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OIR56658.1 - 3e-10 40.4 0.0 3.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OIR56658.1 - 0.013 14.9 0.5 0.14 11.7 0.0 2.0 1 1 0 2 2 2 0 Glycosyl transferase family 21 DUF5616 PF18481.1 OIR56658.1 - 0.045 14.1 0.1 0.063 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) 2OG-FeII_Oxy_4 PF13661.6 OIR56659.1 - 2.4e-25 89.0 0.0 7.5e-25 87.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OIR56659.1 - 7.9e-15 55.5 0.0 1.9e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 OIR56659.1 - 2.2e-10 40.3 0.0 0.00039 19.8 0.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term MuF_C PF18819.1 OIR56660.1 - 0.09 12.8 0.3 5.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Phage MuF-C-terminal domain ZU5 PF00791.20 OIR56660.1 - 0.1 12.9 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 ZU5 domain YacG PF03884.14 OIR56661.1 - 0.00018 21.2 0.0 0.75 9.6 0.0 4.6 5 0 0 5 5 5 1 DNA gyrase inhibitor YacG Methyltransf_1N PF02870.15 OIR56661.1 - 0.032 15.0 0.6 16 6.4 0.0 4.0 4 0 0 4 4 4 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Gemin7 PF11095.8 OIR56661.1 - 0.13 12.2 1.1 4.2 7.3 0.0 3.1 3 1 1 4 4 4 0 Gem-associated protein 7 (Gemin7) Integrase_H2C2 PF17921.1 OIR56662.1 - 0.00063 19.8 0.7 0.001 19.1 0.2 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OIR56662.1 - 0.037 14.2 1.4 0.052 13.8 0.3 1.9 2 1 0 2 2 2 0 H2C2 zinc finger Equine_IAV_S2 PF06502.11 OIR56662.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Rap_GAP PF02145.15 OIR56663.1 - 2.7e-29 102.0 0.2 5.5e-29 101.0 0.2 1.5 1 0 0 1 1 1 1 Rap/ran-GAP CooT PF10133.9 OIR56664.1 - 0.006 16.8 0.0 3.4 8.0 0.0 4.4 5 0 0 5 5 5 1 CO dehydrogenase accessory protein CooT Ski_Sno PF02437.17 OIR56664.1 - 0.12 12.2 0.0 2.5 7.9 0.0 2.7 2 1 1 3 3 3 0 SKI/SNO/DAC family RVT_1 PF00078.27 OIR56668.1 - 3.8e-32 111.6 0.3 3.8e-32 111.6 0.3 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OIR56668.1 - 2.5e-15 56.3 0.0 8.7e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OIR56668.1 - 2.7e-12 47.1 2.0 4.4e-12 46.4 0.8 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56668.1 - 5.4e-10 39.8 2.0 1.6e-09 38.2 1.3 2.1 1 1 1 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 OIR56668.1 - 3.3e-07 30.1 0.0 6.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OIR56668.1 - 7.8e-06 26.1 0.1 2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 OIR56668.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH PF17917.1 OIR56668.1 - 0.00041 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FH2 PF02181.23 OIR56669.1 - 1.5e-41 142.8 4.9 1.5e-41 142.8 4.9 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OIR56669.1 - 8.2e-07 28.8 0.1 2.9e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 Diaphanous FH3 Domain zf-C3HC4_3 PF13920.6 OIR56673.1 - 0.01 15.7 3.8 0.02 14.8 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR56673.1 - 2.8 7.9 4.6 7.4 6.5 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NBD94 PF16830.5 OIR56674.1 - 2.8 8.4 15.0 16 6.0 0.3 4.2 1 1 3 4 4 4 0 Nucleotide-Binding Domain 94 of RH rve PF00665.26 OIR56675.1 - 1.3e-21 77.0 0.0 1.4e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR56675.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain DDE_Tnp_IS240 PF13610.6 OIR56675.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 DDE domain Reg_prop PF07494.11 OIR56676.1 - 6.7e-14 50.3 14.4 1.8 9.1 0.0 9.2 9 1 0 9 9 9 8 Two component regulator propeller BAF250_C PF12031.8 OIR56676.1 - 8.5e-13 48.2 0.0 0.0021 17.4 0.0 5.9 2 1 3 6 6 6 4 SWI/SNF-like complex subunit BAF250/Osa rve PF00665.26 OIR56677.1 - 0.022 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain ABC_tran PF00005.27 OIR56679.1 - 2e-18 67.2 0.2 2.9e-18 66.7 0.2 1.2 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 OIR56679.1 - 5e-05 23.3 0.1 8.1e-05 22.6 0.0 1.4 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 OIR56679.1 - 0.0001 22.8 3.6 0.00018 22.1 0.6 2.0 1 1 0 2 2 2 1 AAA domain cobW PF02492.19 OIR56679.1 - 0.00023 20.8 0.1 0.00033 20.3 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 OIR56679.1 - 0.00081 18.9 0.5 0.0014 18.1 0.5 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OIR56679.1 - 0.00099 19.4 0.5 0.0024 18.2 0.3 2.0 1 1 1 2 2 2 1 AAA domain AAA_21 PF13304.6 OIR56679.1 - 0.0011 18.8 0.2 0.0015 18.4 0.2 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OIR56679.1 - 0.0012 18.8 0.1 0.0022 17.9 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 OIR56679.1 - 0.0058 17.0 0.0 0.0066 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OIR56679.1 - 0.0061 16.1 0.1 0.0069 16.0 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OIR56679.1 - 0.0068 16.8 0.2 0.012 16.1 0.2 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OIR56679.1 - 0.01 15.6 0.1 0.032 14.0 0.1 1.9 1 1 1 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OIR56679.1 - 0.013 15.6 0.3 0.022 14.8 0.3 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 OIR56679.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain DUF3213 PF11491.8 OIR56679.1 - 0.021 15.0 0.2 0.045 13.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3213) Rad51 PF08423.11 OIR56679.1 - 0.029 13.6 0.1 0.041 13.1 0.1 1.2 1 0 0 1 1 1 0 Rad51 PduV-EutP PF10662.9 OIR56679.1 - 0.041 13.6 0.4 0.25 11.1 0.1 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OIR56679.1 - 0.042 14.1 0.3 0.077 13.2 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OIR56679.1 - 0.044 14.3 0.2 0.072 13.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain RecA PF00154.21 OIR56679.1 - 0.051 13.0 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_33 PF13671.6 OIR56679.1 - 0.065 13.4 0.2 0.1 12.8 0.2 1.4 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 OIR56679.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 OIR56679.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 OIR56679.1 - 0.099 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 OIR56679.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.27 OIR56681.1 - 7.8e-36 123.7 0.0 1.2e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OIR56681.1 - 4.6e-05 23.2 0.0 0.00029 20.7 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 OIR56681.1 - 0.037 14.7 0.2 0.12 13.1 0.2 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase GDA1_CD39 PF01150.17 OIR56681.1 - 0.043 12.5 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family TP6A_N PF04406.14 OIR56682.1 - 9.6e-17 60.7 0.1 2.7e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2220 PF09983.9 OIR56682.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Aminotran_5 PF00266.19 OIR56683.1 - 2.2e-92 309.9 0.0 2.5e-92 309.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OIR56683.1 - 1.3e-06 27.9 0.2 1.8e-06 27.4 0.2 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 OIR56683.1 - 0.00044 19.1 0.0 0.00077 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 OIR56683.1 - 0.00065 19.1 0.2 0.00094 18.6 0.2 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 OIR56683.1 - 0.0061 15.1 0.0 0.0094 14.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 OIR56683.1 - 0.13 12.3 0.3 2.4 8.2 0.0 2.7 2 1 1 3 3 3 0 B12 binding domain Ribosomal_L44 PF00935.19 OIR56684.1 - 7.4e-34 116.1 16.2 1e-33 115.6 16.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 CD45 PF12567.8 OIR56684.1 - 0.2 11.6 5.3 1.3 9.1 0.9 2.2 2 0 0 2 2 2 0 Leukocyte receptor CD45 KASH_CCD PF14662.6 OIR56685.1 - 0.068 13.0 3.4 0.13 12.0 3.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BCDHK_Adom3 PF10436.9 OIR56686.1 - 0.018 14.9 0.2 0.029 14.2 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3638 PF12340.8 OIR56686.1 - 0.14 11.4 0.2 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Enolase_C PF00113.22 OIR56687.1 - 1.6e-132 441.3 0.0 2.1e-132 440.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OIR56687.1 - 1.2e-51 174.3 0.0 2e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OIR56687.1 - 1.1e-08 34.9 0.1 2.1e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OIR56687.1 - 0.045 12.9 1.7 0.45 9.6 0.1 2.7 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus rve PF00665.26 OIR56689.1 - 7.9e-22 77.7 0.0 2.2e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OIR56689.1 - 2.9e-06 27.3 0.1 9.7e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain Integrase_Zn PF02022.19 OIR56689.1 - 8.5e-05 22.4 0.1 0.00019 21.3 0.1 1.6 1 0 0 1 1 1 1 Integrase Zinc binding domain rve_3 PF13683.6 OIR56689.1 - 0.002 17.9 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OIR56689.1 - 0.016 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 DDE domain rve PF00665.26 OIR56690.1 - 1.3e-17 64.1 0.0 3.4e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain DUF4638 PF15472.6 OIR56690.1 - 0.052 13.3 1.8 0.073 12.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CagX PF03524.15 OIR56690.1 - 0.061 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Conjugal transfer protein FAM83 PF07894.12 OIR56692.1 - 0.32 10.5 4.6 2.3 7.7 0.1 2.5 2 1 0 2 2 2 0 FAM83 A-H DUF4263 PF14082.6 OIR56695.1 - 0.13 12.5 0.3 0.16 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) DASH_Spc19 PF08287.11 OIR56695.1 - 0.21 11.5 9.0 0.26 11.2 9.0 1.2 1 0 0 1 1 1 0 Spc19 eIF3_subunit PF08597.10 OIR56695.1 - 3.2 7.6 17.4 3.8 7.4 17.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit zf-FCS PF06467.14 OIR56696.1 - 0.11 12.5 2.4 4.1 7.4 0.4 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CCHC_5 PF14787.6 OIR56696.1 - 0.25 11.1 4.1 0.44 10.3 0.6 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Hydrolase PF00702.26 OIR56697.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GPAT_N PF14829.6 OIR56698.1 - 0.059 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal DUF3340 PF11818.8 OIR56698.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Haspin_kinase PF12330.8 OIR56699.1 - 2e-38 132.3 0.0 2.3e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 OIR56699.1 - 6.6e-05 22.4 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OIR56699.1 - 0.00043 20.3 0.0 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR56699.1 - 0.0044 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OIR56699.1 - 0.052 13.1 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MCM PF00493.23 OIR56705.1 - 8.5e-100 332.5 0.0 1.3e-99 331.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OIR56705.1 - 2e-38 131.1 1.5 2e-38 131.1 1.5 2.0 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 OIR56705.1 - 4.3e-24 84.8 0.8 1.7e-23 82.8 0.8 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM6_C PF18263.1 OIR56705.1 - 1.1e-15 57.7 0.4 4.1e-15 55.9 0.4 2.0 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 OIR56705.1 - 6.8e-13 49.1 0.0 2.1e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 OIR56705.1 - 6.9e-09 35.4 0.0 1.8e-07 30.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OIR56705.1 - 4e-05 23.6 0.0 0.00011 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OIR56705.1 - 7.6e-05 22.5 0.1 0.00024 20.9 0.1 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OIR56705.1 - 0.0007 19.5 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIG-S PF10510.9 OIR56705.1 - 0.089 11.6 0.6 0.9 8.3 0.1 2.0 1 1 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein zf-C3HC4_3 PF13920.6 OIR56706.1 - 0.00022 21.0 2.5 0.00041 20.1 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR56706.1 - 0.025 14.9 4.0 0.059 13.7 4.0 1.7 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 OIR56706.1 - 0.67 9.9 4.6 1.4 8.8 4.6 1.6 1 0 0 1 1 1 0 PHD-finger RVT_1 PF00078.27 OIR56707.1 - 1.9e-34 119.1 0.0 3.6e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OIR56707.1 - 7e-28 96.6 0.0 2.2e-27 95.0 0.0 2.0 2 0 0 2 2 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OIR56707.1 - 2.3e-27 95.3 0.0 7.2e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OIR56707.1 - 4.4e-23 81.7 0.0 1.2e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OIR56707.1 - 6.4e-15 55.0 0.4 2e-14 53.5 0.4 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OIR56707.1 - 6.1e-11 42.7 0.0 2e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OIR56707.1 - 2.9e-10 40.2 2.1 3.9e-10 39.8 0.2 2.3 3 0 0 3 3 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 OIR56707.1 - 6e-10 39.3 0.0 1.6e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 OIR56707.1 - 3.4e-09 37.2 0.0 1.1e-08 35.6 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OIR56707.1 - 8.8e-09 35.2 0.0 2.1e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease zf-CCHC PF00098.23 OIR56707.1 - 1.6e-05 24.7 2.5 3.3e-05 23.8 2.5 1.6 1 0 0 1 1 1 1 Zinc knuckle DDE_3 PF13358.6 OIR56707.1 - 0.00012 21.8 0.1 0.4 10.4 0.0 2.8 3 0 0 3 3 3 2 DDE superfamily endonuclease DDE_Tnp_IS1595 PF12762.7 OIR56707.1 - 0.00085 19.4 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 ISXO2-like transposase domain Asp_protease PF09668.10 OIR56707.1 - 0.0037 17.0 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A3 PF02160.15 OIR56707.1 - 0.01 15.3 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) MLVIN_C PF18697.1 OIR56707.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain rve_3 PF13683.6 OIR56707.1 - 0.029 14.1 0.0 0.087 12.6 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain HTH_22 PF13309.6 OIR56707.1 - 0.067 13.3 0.3 0.38 10.9 0.0 2.5 2 0 0 2 2 1 0 HTH domain HscB_4_cys PF18256.1 OIR56707.1 - 0.18 11.6 2.3 0.51 10.2 2.3 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DUF3381 PF11861.8 OIR56708.1 - 0.0056 16.5 1.1 0.64 9.8 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3381) Xrn1_D3 PF18194.1 OIR56708.1 - 0.049 13.7 0.2 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 Exoribonuclease 1 Domain-3 Reg_prop PF07494.11 OIR56708.1 - 0.14 12.4 0.0 48 4.7 0.0 3.7 3 1 0 3 3 3 0 Two component regulator propeller RVT_1 PF00078.27 OIR56709.1 - 0.00013 21.6 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_rich_CPCC PF14206.6 OIR56710.1 - 0.23 11.3 1.5 0.48 10.3 0.6 1.9 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-RVT PF13966.6 OIR56710.1 - 0.33 11.7 1.6 0.51 11.1 1.6 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase OrfB_Zn_ribbon PF07282.11 OIR56710.1 - 0.49 10.4 1.6 0.8 9.7 1.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_S14 PF00253.21 OIR56710.1 - 3.7 7.4 5.0 12 5.8 0.2 2.9 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e RVT_1 PF00078.27 OIR56712.1 - 1.8e-38 132.3 0.0 2.6e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OIR56712.1 - 1.5e-05 24.7 0.0 0.00024 20.7 0.0 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Asp-B-Hydro_N PF05279.11 OIR56713.1 - 0.11 12.5 14.4 0.16 12.0 14.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Atg14 PF10186.9 OIR56713.1 - 1 8.4 7.3 1.4 7.9 7.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5302 PF17227.2 OIR56713.1 - 5.1 8.2 8.8 1.2 10.1 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5302) DUF4554 PF15091.6 OIR56713.1 - 5.8 5.7 5.2 8.6 5.1 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) PseudoU_synth_2 PF00849.22 OIR56714.1 - 3.9e-28 98.5 0.0 5.2e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase TehB PF03848.14 OIR56714.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB RsgA_N PF16745.5 OIR56714.1 - 0.1 12.3 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 RsgA N-terminal domain UCH PF00443.29 OIR56716.1 - 2.2e-18 66.7 0.8 3.3e-12 46.4 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR56716.1 - 4.7e-05 23.1 0.6 0.00015 21.5 0.2 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OIR56716.1 - 0.014 14.9 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MAM1 PF10434.9 OIR56716.1 - 0.027 14.1 0.2 0.047 13.3 0.0 1.5 2 0 0 2 2 2 0 Monopolin complex protein MAM1 SIX1_SD PF16878.5 OIR56716.1 - 0.041 14.4 1.2 0.85 10.2 0.1 2.8 3 1 0 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain Spore_III_AB PF09548.10 OIR56716.1 - 0.11 12.6 1.8 5.9 7.0 0.6 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) UCH PF00443.29 OIR56717.1 - 9.5e-21 74.4 0.9 1.1e-18 67.6 0.9 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR56717.1 - 6.2e-07 29.3 0.3 6.4e-06 26.0 0.0 2.1 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SpoIIIAH PF12685.7 OIR56717.1 - 0.013 15.3 0.2 0.026 14.3 0.2 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Peptidase_C98 PF15499.6 OIR56717.1 - 0.048 13.1 0.0 0.23 10.9 0.0 2.0 2 1 1 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Vpu PF00558.19 OIR56717.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.4 3 0 0 3 3 3 0 Vpu protein OrfB_Zn_ribbon PF07282.11 OIR56720.1 - 0.15 12.0 1.0 0.23 11.4 1.0 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RVT_1 PF00078.27 OIR56721.1 - 5.8e-41 140.4 0.0 7.6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zinc_ribbon_12 PF11331.8 OIR56725.1 - 0.072 12.9 5.4 0.21 11.4 5.4 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain MlaD PF02470.20 OIR56725.1 - 0.14 12.5 0.0 69 3.8 0.0 3.6 4 0 0 4 4 4 0 MlaD protein CENP-H PF05837.12 OIR56725.1 - 0.35 11.3 3.1 1.5 9.2 0.2 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Sec6 PF06046.13 OIR56731.1 - 5.5e-55 186.8 0.0 3.8e-54 184.1 0.0 1.9 1 1 1 2 2 2 1 Exocyst complex component Sec6 MiaE_2 PF13794.6 OIR56731.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Rep_fac_C PF08542.11 OIR56731.1 - 0.14 12.6 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Replication factor C C-terminal domain zf-C3HC4_3 PF13920.6 OIR56732.1 - 0.073 12.9 4.3 0.15 11.9 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56732.1 - 0.32 11.1 3.3 1 9.5 3.3 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger EF-hand_7 PF13499.6 OIR56733.1 - 1.2e-18 67.3 1.0 1.6e-10 41.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OIR56733.1 - 3.9e-16 57.5 0.1 0.00019 21.1 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 OIR56733.1 - 7.8e-16 56.4 0.1 0.00012 21.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OIR56733.1 - 2.1e-10 40.7 0.0 7.1e-06 26.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OIR56733.1 - 7.7e-10 38.5 0.8 1.9e-05 24.4 0.0 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OIR56733.1 - 0.014 14.8 0.6 8.8 6.0 0.0 3.6 3 0 0 3 3 3 0 EF hand SPARC_Ca_bdg PF10591.9 OIR56733.1 - 0.018 15.4 0.1 0.08 13.3 0.0 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OIR56733.1 - 0.043 14.7 0.0 0.088 13.7 0.0 1.5 1 1 1 2 2 2 0 EF-hand domain GPHH PF16905.5 OIR56733.1 - 0.15 11.9 0.0 63 3.5 0.0 3.2 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated UDPG_MGDP_dh_N PF03721.14 OIR56734.1 - 5.8e-56 189.0 0.2 1.3e-55 187.9 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 OIR56734.1 - 7.4e-29 99.8 0.0 1.5e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OIR56734.1 - 1.8e-28 99.0 0.1 1.7e-27 95.9 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 OIR56734.1 - 0.0015 19.1 0.1 0.49 11.0 0.0 3.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OIR56734.1 - 0.0048 16.9 0.2 0.14 12.2 0.0 2.8 4 0 0 4 4 4 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 OIR56734.1 - 0.018 15.2 0.1 0.085 13.0 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 OIR56734.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PIG-X PF08320.12 OIR56737.1 - 1.8e-12 47.7 1.7 1e-11 45.2 0.2 2.0 1 1 1 2 2 2 1 PIG-X / PBN1 IL28A PF15177.6 OIR56737.1 - 0.13 12.1 0.2 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 Interleukin-28A FUSC PF04632.12 OIR56738.1 - 0.24 9.9 1.0 0.29 9.6 1.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TolA_bind_tri PF16331.5 OIR56738.1 - 1.1 9.4 9.0 0.56 10.3 0.1 3.5 2 1 1 3 3 3 0 TolA binding protein trimerisation CHDNT PF08073.12 OIR56742.1 - 0.0003 20.7 0.0 20 5.3 0.0 5.0 5 0 0 5 5 5 1 CHDNT (NUC034) domain zf-RING_14 PF17978.1 OIR56742.1 - 0.0043 17.4 0.7 0.22 12.0 0.2 3.6 5 0 0 5 5 5 1 RING/Ubox like zinc-binding domain DUF2247 PF10004.9 OIR56742.1 - 0.11 12.3 4.0 2.8 7.7 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2247) zf-C3HC4_3 PF13920.6 OIR56742.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 OIR56743.1 - 2.7e-27 95.9 7.7 3.2e-26 92.4 7.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR56743.1 - 2e-06 27.6 6.1 0.00058 19.5 1.8 2.9 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OIR56743.1 - 0.0032 17.0 0.7 0.046 13.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase ANAPC4 PF12896.7 OIR56743.1 - 0.038 13.5 0.6 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 MAAL_C PF07476.11 OIR56743.1 - 0.14 11.3 0.1 3.4 6.8 0.1 2.1 1 1 1 2 2 2 0 Methylaspartate ammonia-lyase C-terminus zf-RVT PF13966.6 OIR56748.1 - 0.0015 19.2 0.1 0.0046 17.6 0.0 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Mor PF08765.11 OIR56749.1 - 0.0039 17.2 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 1 Mor transcription activator family RT_RNaseH PF17917.1 OIR56751.1 - 1.9e-38 130.9 0.0 5.4e-38 129.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OIR56751.1 - 1.4e-35 121.4 0.0 4.1e-35 119.8 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OIR56751.1 - 1.7e-33 116.0 0.0 4e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OIR56751.1 - 1.1e-27 96.6 0.0 3.2e-27 95.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.6 OIR56751.1 - 8.8e-09 35.8 0.1 2.2e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56751.1 - 6e-08 33.2 0.1 2.6e-07 31.2 0.2 2.1 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 OIR56751.1 - 0.00033 20.4 0.0 0.0013 18.4 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OIR56751.1 - 0.00065 19.8 0.1 0.0019 18.3 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain DDE_3 PF13358.6 OIR56751.1 - 0.0033 17.2 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease zf-CCHC_3 PF13917.6 OIR56751.1 - 0.0077 16.2 4.3 0.017 15.1 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OIR56751.1 - 0.017 15.2 3.8 0.031 14.3 3.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.20 OIR56751.1 - 0.017 15.4 0.0 0.055 13.8 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 OIR56751.1 - 0.036 13.8 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-C2H2_10 PF16588.5 OIR56751.1 - 0.26 11.0 5.7 0.66 9.7 5.7 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger MTS PF05175.14 OIR56752.1 - 1.4e-07 31.2 0.0 2.1e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain UPF0020 PF01170.18 OIR56752.1 - 0.0077 15.9 0.0 0.014 15.0 0.0 1.5 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 OIR56752.1 - 0.0086 16.8 0.0 0.039 14.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_33 PF10017.9 OIR56752.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.3 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent rRNA_methylase PF06962.12 OIR56752.1 - 0.015 15.3 0.0 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Putative rRNA methylase DUF938 PF06080.12 OIR56752.1 - 0.017 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CmcI PF04989.12 OIR56752.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_18 PF12847.7 OIR56752.1 - 0.073 13.0 0.0 1.2 9.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Fibrinogen_BP PF08017.11 OIR56753.1 - 0.07 11.6 22.3 0.085 11.3 22.3 1.1 1 0 0 1 1 1 0 Fibrinogen binding protein GLE1 PF07817.13 OIR56754.1 - 6e-54 182.9 0.9 6e-54 182.9 0.9 1.5 2 0 0 2 2 2 1 GLE1-like protein DUF1283 PF06932.11 OIR56754.1 - 0.078 13.2 3.2 0.22 11.8 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1283) DUF4051 PF13260.6 OIR56754.1 - 0.18 11.5 0.3 0.57 9.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) CLZ PF16526.5 OIR56754.1 - 1.8 9.0 14.5 0.035 14.5 6.1 2.5 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bromo_TP PF07524.13 OIR56755.1 - 2.5e-13 49.8 0.0 5.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 OIR56755.1 - 1.2e-05 25.5 0.6 2.1e-05 24.7 0.6 1.3 1 0 0 1 1 1 1 Histone-fold protein TAF8_C PF10406.9 OIR56755.1 - 2.7e-05 24.7 0.1 5.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term CBFD_NFYB_HMF PF00808.23 OIR56755.1 - 0.00094 19.4 0.0 0.0084 16.4 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 OIR56755.1 - 0.0011 19.0 0.2 0.0019 18.3 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OIR56755.1 - 0.0018 18.3 0.3 0.0025 17.9 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 OIR56755.1 - 0.0096 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Chorismate_bind PF00425.18 OIR56755.1 - 0.05 13.2 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 chorismate binding enzyme Histone PF00125.24 OIR56755.1 - 0.057 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.11 OIR56755.1 - 0.057 13.5 0.3 0.12 12.4 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1931) TFIID_20kDa PF03847.13 OIR56755.1 - 0.091 13.3 0.2 0.091 13.3 0.2 1.8 2 1 0 2 2 1 0 Transcription initiation factor TFIID subunit A tRNA_int_end_N2 PF12928.7 OIR56756.1 - 0.0006 19.9 0.1 0.0012 19.0 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Q_salvage PF10343.9 OIR56757.1 - 0.0042 16.7 0.1 0.0044 16.6 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Tox-ODYAM1 PF15642.6 OIR56757.1 - 0.0054 15.8 0.2 0.006 15.6 0.2 1.0 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus DivIC PF04977.15 OIR56757.1 - 0.011 15.5 0.9 0.011 15.5 0.9 1.5 2 0 0 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 OIR56757.1 - 0.094 13.2 0.1 0.12 12.9 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Synaptobrevin PF00957.21 OIR56757.1 - 0.17 11.7 1.4 0.42 10.4 1.4 1.6 1 1 0 1 1 1 0 Synaptobrevin DUF4428 PF14471.6 OIR56758.1 - 0.00024 20.9 0.5 0.00071 19.4 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) zf-SNAP50_C PF12251.8 OIR56758.1 - 0.0013 18.5 0.2 0.002 17.8 0.2 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal zf-C4_ClpX PF06689.13 OIR56758.1 - 0.022 14.6 1.8 0.071 13.0 1.8 1.8 1 0 0 1 1 1 0 ClpX C4-type zinc finger MazE_antitoxin PF04014.18 OIR56760.1 - 0.16 12.0 0.5 40 4.3 0.1 3.5 3 0 0 3 3 3 0 Antidote-toxin recognition MazE, bacterial antitoxin zf-C3HC4_3 PF13920.6 OIR56761.1 - 2.4e-05 24.1 6.3 7.8e-05 22.5 6.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BAF250_C PF12031.8 OIR56761.1 - 0.00095 18.5 0.2 9.4 5.4 0.0 4.2 2 2 1 4 4 4 1 SWI/SNF-like complex subunit BAF250/Osa zf-UDP PF14569.6 OIR56761.1 - 0.0064 16.6 3.7 0.0064 16.6 3.7 2.1 2 0 0 2 2 2 1 Zinc-binding RING-finger DUF2110 PF09883.9 OIR56761.1 - 0.01 15.4 0.2 9 5.8 0.0 3.5 1 1 3 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2110) zf-RING_2 PF13639.6 OIR56761.1 - 0.016 15.6 7.5 0.037 14.3 7.5 1.7 1 0 0 1 1 1 0 Ring finger domain GcrA PF07750.11 OIR56761.1 - 0.049 14.1 1.6 49 4.3 0.0 4.4 4 1 0 5 5 5 0 GcrA cell cycle regulator zf-Di19 PF05605.12 OIR56761.1 - 0.16 12.3 3.1 2.8 8.3 0.1 2.7 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 OIR56761.1 - 0.24 11.2 5.9 0.77 9.6 5.9 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nucleic_acid_bd PF13820.6 OIR56761.1 - 0.4 10.5 3.4 1.2e+02 2.5 0.0 4.4 3 1 0 4 4 4 0 Putative nucleic acid-binding region Reg_prop PF07494.11 OIR56761.1 - 0.55 10.6 3.1 1.4e+02 3.3 0.0 4.8 6 0 0 6 6 6 0 Two component regulator propeller DUF2197 PF09963.9 OIR56761.1 - 1 9.7 4.2 3.2 8.1 4.2 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C3HC4_4 PF15227.6 OIR56761.1 - 3.3 8.0 8.4 0.14 12.3 1.7 2.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING CRS1_YhbY PF01985.21 OIR56762.1 - 0.038 14.1 0.7 2.4 8.4 0.0 3.5 2 2 2 4 4 4 0 CRS1 / YhbY (CRM) domain Reg_prop PF07494.11 OIR56762.1 - 0.1 12.9 0.7 3.6e+02 2.0 0.0 4.5 5 0 0 5 5 5 0 Two component regulator propeller EXOSC1 PF10447.9 OIR56762.1 - 0.11 13.2 0.0 11 6.7 0.0 3.0 1 1 2 3 3 3 0 Exosome component EXOSC1/CSL4 Pkinase PF00069.25 OIR56763.1 - 1.7e-12 47.3 0.1 2e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56763.1 - 9e-07 28.4 0.0 1.1e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase CLU_N PF15044.6 OIR56763.1 - 0.0055 17.0 0.5 0.0082 16.5 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term Ribosomal_L21e PF01157.18 OIR56763.1 - 0.022 14.6 0.6 0.032 14.1 0.6 1.3 1 1 0 1 1 1 0 Ribosomal protein L21e Proteasom_Rpn13 PF04683.13 OIR56763.1 - 0.087 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Pkinase PF00069.25 OIR56764.1 - 1.3e-31 109.9 0.3 5.7e-31 107.8 0.6 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56764.1 - 1.5e-20 73.6 0.1 2.3e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56764.1 - 4e-08 32.9 0.1 6.8e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56764.1 - 0.0026 17.4 0.9 0.0048 16.5 0.9 1.3 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OIR56764.1 - 0.037 13.4 0.0 0.19 11.0 0.0 1.8 1 1 1 2 2 2 0 Kinase-like EcKinase PF02958.20 OIR56764.1 - 0.08 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.23 OIR56764.1 - 0.17 11.8 0.1 4.2 7.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 OIR56765.1 - 4.2e-33 114.8 9.4 7.1e-32 110.8 6.9 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56765.1 - 8.3e-22 77.7 1.2 1.2e-21 77.1 1.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56765.1 - 0.00028 20.3 0.2 0.00061 19.2 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56765.1 - 0.00031 20.4 0.9 0.00043 19.9 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OIR56765.1 - 0.18 11.7 0.1 0.44 10.4 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ferritin-like PF12902.7 OIR56766.1 - 0.0043 17.0 4.0 0.0043 17.0 4.0 1.5 1 1 0 1 1 1 1 Ferritin-like DUF1741 PF08427.10 OIR56766.1 - 0.014 15.1 1.1 0.022 14.4 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) EcKinase PF02958.20 OIR56766.1 - 0.022 14.1 2.7 0.03 13.6 2.7 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1206 PF06724.11 OIR56766.1 - 0.032 14.3 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF713 PF05218.14 OIR56766.1 - 0.035 13.9 5.7 0.052 13.3 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Sulfotransfer_4 PF17784.1 OIR56766.1 - 0.044 13.6 1.0 2.7 7.7 0.2 2.2 1 1 1 2 2 2 0 Sulfotransferase domain DUF4071 PF13281.6 OIR56766.1 - 0.052 12.6 1.8 0.069 12.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF3729 PF12526.8 OIR56766.1 - 1.6 10.3 9.9 3.5 9.2 9.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) DNA_repr_REX1B PF14966.6 OIR56766.1 - 3.1 8.5 8.4 2.3 8.9 3.5 2.3 1 1 1 2 2 2 0 DNA repair REX1-B Ran-binding PF05508.11 OIR56767.1 - 0.11 11.5 1.2 1.7 7.5 0.1 2.6 2 0 0 2 2 2 0 RanGTP-binding protein DUF948 PF06103.11 OIR56767.1 - 0.81 10.0 7.2 19 5.6 0.1 4.2 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.6 OIR56767.1 - 5.3 7.1 21.1 1.9 8.6 11.7 3.8 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 PAC3 PF10178.9 OIR56770.1 - 0.12 12.6 0.2 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 RNA_pol_Rpb4 PF03874.16 OIR56771.1 - 0.039 14.3 0.4 0.27 11.6 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb4 Cu_amine_oxidN2 PF02727.16 OIR56773.1 - 0.043 14.0 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain BRCT PF00533.26 OIR56774.1 - 2e-33 114.6 0.9 2.7e-14 53.3 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OIR56774.1 - 3.8e-31 107.3 0.0 5.9e-06 26.6 0.0 5.2 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 OIR56774.1 - 7.4e-27 93.1 3.5 3.9e-16 58.8 0.2 4.5 4 1 0 4 4 4 3 twin BRCT domain LIG3_BRCT PF16759.5 OIR56774.1 - 6.8e-10 39.1 0.3 0.022 15.0 0.0 4.1 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 OIR56774.1 - 5.1e-06 26.5 0.0 0.093 12.8 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 OIR56774.1 - 0.037 14.4 0.0 2.9 8.3 0.0 3.1 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein RTT107_BRCT_5 PF16770.5 OIR56774.1 - 0.092 12.6 0.0 2.2 8.2 0.0 3.0 4 0 0 4 4 4 0 Regulator of Ty1 transposition protein 107 BRCT domain DEAD PF00270.29 OIR56775.1 - 1.3e-48 165.1 0.0 2.5e-48 164.2 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR56775.1 - 2.4e-31 108.3 0.0 5.2e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR56775.1 - 0.0012 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OIR56775.1 - 0.0049 16.1 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 OIR56775.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PHD PF00628.29 OIR56776.1 - 0.15 11.9 11.0 0.52 10.3 10.4 2.0 2 0 0 2 2 2 0 PHD-finger MoaE PF02391.17 OIR56777.1 - 0.064 13.5 0.0 0.42 10.9 0.0 2.0 2 0 0 2 2 2 0 MoaE protein Nucleic_acid_bd PF13820.6 OIR56777.1 - 1.2 9.0 3.1 82 3.0 0.0 3.6 3 1 1 4 4 4 0 Putative nucleic acid-binding region TPR_11 PF13414.6 OIR56779.1 - 0.045 13.4 0.8 4.7 7.0 0.2 2.2 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 OIR56779.1 - 0.062 13.5 0.2 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OIR56779.1 - 0.12 13.2 0.2 0.49 11.4 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat VIR_N PF15912.5 OIR56780.1 - 0.1 12.2 8.1 0.12 12.0 8.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Muted PF14942.6 OIR56781.1 - 0.37 11.1 4.2 2.3 8.6 2.9 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3391 PF11871.8 OIR56781.1 - 6.6 7.3 7.9 4.9 7.7 5.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) CDC45 PF02724.14 OIR56782.1 - 7.5e-05 21.2 7.3 9.2e-05 20.9 7.3 1.1 1 0 0 1 1 1 1 CDC45-like protein LAP1C PF05609.12 OIR56782.1 - 0.0015 17.8 4.9 0.0021 17.2 4.9 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF2207 PF09972.9 OIR56782.1 - 0.0028 16.5 0.3 0.013 14.3 0.2 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF3377 PF11857.8 OIR56782.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4519 PF15012.6 OIR56782.1 - 0.025 14.7 1.2 0.025 14.7 1.2 2.5 2 1 0 2 2 1 0 Domain of unknown function (DUF4519) Zip PF02535.22 OIR56782.1 - 0.026 13.8 5.1 0.039 13.2 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Orf78 PF06024.12 OIR56782.1 - 0.034 14.4 7.5 0.66 10.3 7.5 2.4 1 1 0 1 1 1 0 Orf78 (ac78) SafA PF17073.5 OIR56782.1 - 0.039 13.9 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Two-component-system connector protein DUF1180 PF06679.12 OIR56782.1 - 0.045 14.2 0.9 0.077 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DHHC PF01529.20 OIR56782.1 - 0.051 13.7 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase CSG2 PF16965.5 OIR56782.1 - 0.23 10.4 2.2 0.36 9.7 2.2 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator E1-E2_ATPase PF00122.20 OIR56782.1 - 0.38 10.3 1.2 1.1 8.7 0.5 2.0 2 1 1 3 3 3 0 E1-E2 ATPase TRIQK PF15168.6 OIR56782.1 - 0.4 10.6 5.4 0.14 12.0 1.6 2.2 1 1 1 2 2 2 0 Triple QxxK/R motif-containing protein family Consortin_C PF15281.6 OIR56782.1 - 0.41 10.6 4.1 0.18 11.8 0.4 2.0 1 1 1 2 2 2 0 Consortin C-terminus TM2 PF05154.16 OIR56782.1 - 0.9 9.9 4.5 0.59 10.5 1.6 2.0 2 0 0 2 2 2 0 TM2 domain CrgA PF06781.12 OIR56782.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Cell division protein CrgA RR_TM4-6 PF06459.12 OIR56782.1 - 1.3 8.8 12.3 2.7 7.7 12.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 OIR56782.1 - 1.9 7.4 10.8 3.2 6.7 10.8 1.4 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 OIR56782.1 - 2.3 6.9 15.6 3.3 6.4 15.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ALMT PF11744.8 OIR56782.1 - 2.9 6.6 7.8 4.1 6.1 7.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter LRRC37AB_C PF14914.6 OIR56782.1 - 8.4 6.3 11.8 0.3 11.0 2.7 2.3 1 1 1 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Med9 PF07544.13 OIR56783.1 - 0.041 14.0 1.1 0.041 14.0 1.1 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TOH_N PF12549.8 OIR56783.1 - 0.078 12.8 0.4 0.2 11.6 0.4 1.7 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Atg14 PF10186.9 OIR56783.1 - 0.36 9.9 8.4 0.073 12.2 4.7 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_1 PF00078.27 OIR56784.1 - 8.2e-41 139.9 0.0 1.2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OIR56784.1 - 4.3e-06 26.4 0.0 3.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OIR56784.1 - 0.00027 20.7 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 OIR56785.1 - 0.17 12.6 2.1 0.5 11.1 2.1 2.0 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase WD40 PF00400.32 OIR56787.1 - 6.6e-17 61.6 13.4 8e-05 23.3 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR56787.1 - 4.6e-16 58.9 0.5 4.5e-06 26.9 0.2 4.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OIR56787.1 - 1.7e-06 27.3 0.1 0.04 12.9 0.0 3.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OIR56787.1 - 0.0019 18.1 0.0 0.17 11.8 0.0 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 OIR56787.1 - 0.019 13.6 0.0 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin NifZ PF04319.13 OIR56787.1 - 0.16 11.8 0.4 9.9 6.0 0.1 3.1 3 0 0 3 3 3 0 NifZ domain Ribosomal_L13 PF00572.18 OIR56788.1 - 1.9e-05 24.9 1.7 0.00027 21.2 0.4 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 Terminase_GpA PF05876.12 OIR56789.1 - 0.032 12.8 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) APG6_N PF17675.1 OIR56789.1 - 0.035 14.6 3.3 0.24 12.0 0.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region P4Ha_N PF08336.11 OIR56789.1 - 0.036 14.1 0.3 0.55 10.3 0.1 2.2 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TPR_MLP1_2 PF07926.12 OIR56789.1 - 0.78 9.8 4.8 0.47 10.5 0.4 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Ufd2P_core PF10408.9 OIR56790.1 - 2e-87 294.3 0.0 2.8e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OIR56790.1 - 4.9e-26 90.7 0.6 1.4e-25 89.3 0.6 1.8 1 0 0 1 1 1 1 U-box domain RasGEF PF00617.19 OIR56790.1 - 0.044 14.0 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 RasGEF domain Utp11 PF03998.13 OIR56791.1 - 2.7e-29 102.9 17.9 4.4e-29 102.1 17.9 1.4 1 1 0 1 1 1 1 Utp11 protein Thioredoxin PF00085.20 OIR56792.1 - 8.7e-11 41.7 0.1 1.2e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OIR56792.1 - 0.0001 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OIR56792.1 - 0.0017 18.6 0.1 0.0042 17.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 OIR56792.1 - 0.003 17.7 0.2 0.0086 16.3 0.2 1.7 1 1 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 OIR56792.1 - 0.0086 15.8 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 OIR56792.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 OIR56792.1 - 0.31 11.5 1.8 0.54 10.7 0.1 2.1 2 1 0 2 2 2 0 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OIR56793.1 - 1.9e-15 57.1 1.6 1.5e-13 50.9 1.6 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 OIR56793.1 - 0.0046 17.0 0.1 0.0081 16.2 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-RVT PF13966.6 OIR56794.1 - 0.0069 17.1 1.9 0.013 16.2 1.3 1.7 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR56794.1 - 0.15 12.0 2.4 0.29 11.2 2.4 1.4 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Glyco_transf_64 PF09258.10 OIR56795.1 - 1.7e-06 27.5 0.0 2.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Thioredoxin PF00085.20 OIR56796.1 - 0.00059 19.8 0.0 0.00093 19.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DeoC PF01791.9 OIR56796.1 - 0.025 14.2 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 DeoC/LacD family aldolase MetOD2 PF18548.1 OIR56796.1 - 0.092 12.9 0.1 0.29 11.3 0.1 1.8 2 0 0 2 2 2 0 Metanogen output domain 2 PMP1_2 PF08114.11 OIR56797.1 - 0.011 15.5 1.6 0.017 14.8 1.6 1.3 1 0 0 1 1 1 0 ATPase proteolipid family TIR_3 PF18567.1 OIR56797.1 - 0.038 14.0 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain P2_N PF18628.1 OIR56800.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain CLP_protease PF00574.23 OIR56802.1 - 0.0045 16.9 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease ABC_tran PF00005.27 OIR56803.1 - 1.8e-12 48.0 0.0 2.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OIR56803.1 - 0.00059 19.3 0.1 0.0007 19.1 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OIR56803.1 - 0.0043 16.9 0.0 0.005 16.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OIR56803.1 - 0.013 15.7 0.1 0.1 12.8 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 OIR56803.1 - 0.023 14.5 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3071 PF11268.8 OIR56804.1 - 0.21 11.7 1.1 0.38 10.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) CM_2 PF01817.21 OIR56804.1 - 0.35 11.2 5.9 8.8 6.8 1.5 3.1 1 1 2 3 3 3 0 Chorismate mutase type II UTRA PF07702.13 OIR56804.1 - 2.5 8.0 11.9 6.2 6.7 0.5 3.3 1 1 3 4 4 4 0 UTRA domain SurA_N_3 PF13624.6 OIR56804.1 - 2.6 7.8 9.4 43 3.9 9.4 2.8 1 1 0 1 1 1 0 SurA N-terminal domain CAF1 PF04857.20 OIR56806.1 - 1.3e-17 64.0 1.5 2.4e-10 40.1 1.3 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease RNase_T PF00929.24 OIR56806.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 Exonuclease Neuralized PF07177.12 OIR56806.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Neuralized DnaJ_C PF01556.18 OIR56807.1 - 6.2e-33 114.0 2.8 8.5e-33 113.5 2.8 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OIR56807.1 - 1.3e-24 86.0 1.0 2.3e-24 85.3 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OIR56807.1 - 7e-12 45.5 18.0 1.6e-11 44.4 18.0 1.6 1 0 0 1 1 1 1 DnaJ central domain zf-RING_10 PF16685.5 OIR56807.1 - 0.0022 18.1 1.5 0.0022 18.1 1.5 2.9 2 1 0 2 2 2 1 zinc RING finger of MSL2 Anti-TRAP PF15777.5 OIR56807.1 - 0.011 15.7 9.5 0.5 10.4 2.0 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein A2L_zn_ribbon PF08792.10 OIR56807.1 - 0.99 9.2 15.0 0.096 12.4 2.8 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain MFS_1_like PF12832.7 OIR56808.1 - 1.8e-13 50.1 15.4 2.5e-13 49.7 15.4 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OIR56808.1 - 1.5e-11 43.9 15.0 1.5e-10 40.6 3.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 OIR56808.1 - 0.028 13.4 13.8 0.044 12.8 13.7 1.3 1 1 0 1 1 1 0 Nucleoside H+ symporter DUF202 PF02656.15 OIR56808.1 - 4.1 7.9 5.8 43 4.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF202) DUF1772 PF08592.11 OIR56808.1 - 5.3 7.4 9.6 4.9 7.5 0.0 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) Cnd1 PF12717.7 OIR56809.1 - 2e-05 24.7 0.1 0.0051 16.9 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CBF PF03914.17 OIR56809.1 - 6.5e-05 23.0 1.0 0.2 11.7 0.0 3.1 2 1 1 3 3 3 2 CBF/Mak21 family DUF3731 PF12531.8 OIR56809.1 - 0.0098 15.7 0.0 0.03 14.1 0.0 1.8 1 1 0 1 1 1 1 DNA-K related protein Adaptin_N PF01602.20 OIR56809.1 - 0.011 14.3 0.0 0.034 12.7 0.0 1.8 2 0 0 2 2 2 0 Adaptin N terminal region DUF4378 PF14309.6 OIR56809.1 - 0.013 15.9 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) RRM_1 PF00076.22 OIR56810.1 - 3.5e-22 78.0 0.0 6.1e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OIR56810.1 - 0.00014 21.3 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 OIR56810.1 - 0.00088 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 OIR56810.1 - 0.021 14.7 0.0 0.077 12.9 0.0 1.9 1 1 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OIR56810.1 - 0.03 14.4 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 Pkinase PF00069.25 OIR56811.1 - 2.2e-29 102.6 0.0 9.9e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56811.1 - 2.2e-14 53.4 0.0 7.1e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OIR56811.1 - 2.4e-05 23.8 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR56811.1 - 0.014 15.0 0.1 0.22 11.2 0.1 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OIR56811.1 - 0.019 14.9 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OIR56811.1 - 0.056 13.0 0.1 0.24 11.0 0.1 1.9 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 OIR56812.1 - 2.5e-34 118.9 0.6 3.3e-34 118.5 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56812.1 - 5.7e-20 71.7 0.6 7.8e-20 71.2 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OIR56812.1 - 0.00026 20.4 0.2 0.00039 19.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR56812.1 - 0.00043 19.9 0.2 0.0014 18.3 0.2 1.7 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OIR56812.1 - 0.00086 18.3 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56812.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OIR56812.1 - 0.039 13.0 0.5 0.064 12.3 0.2 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 OIR56812.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Proteasom_Rpn13 PF04683.13 OIR56812.1 - 0.12 12.9 0.0 4.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor Pkinase PF00069.25 OIR56813.1 - 3.7e-30 105.2 0.3 8.9e-29 100.7 0.6 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56813.1 - 6.7e-18 64.9 0.2 1.3e-17 64.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56813.1 - 3.9e-05 23.1 0.1 6.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OIR56813.1 - 0.032 13.8 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 OIR56813.1 - 0.092 12.3 1.1 0.32 10.5 0.2 1.9 1 1 1 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 OIR56813.1 - 0.13 11.1 0.7 0.21 10.5 0.3 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 OIR56814.1 - 1.6e-36 126.1 0.0 3.3e-36 125.0 0.1 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56814.1 - 1e-18 67.6 0.0 1.3e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56814.1 - 5.5e-06 25.9 0.1 8.3e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR56814.1 - 2.6e-05 24.0 0.1 0.098 12.3 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OIR56814.1 - 0.00025 20.1 0.1 0.00033 19.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR56814.1 - 0.00028 20.9 0.1 0.00083 19.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OIR56814.1 - 0.017 14.7 0.1 0.038 13.6 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 OIR56814.1 - 0.027 13.8 0.0 0.23 10.7 0.0 2.1 1 1 1 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 OIR56814.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 OIR56814.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 OIR56814.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 OIR56815.1 - 3.9e-20 72.3 0.0 5.2e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56815.1 - 8.7e-10 38.3 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56815.1 - 0.014 14.8 0.8 0.02 14.2 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family OAD_gamma PF04277.13 OIR56816.1 - 0.063 13.9 0.4 0.11 13.2 0.4 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain B277 PF17623.2 OIR56817.1 - 0.019 14.1 0.1 0.024 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function CopG_antitoxin PF12441.8 OIR56817.1 - 0.075 13.6 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system Latarcin PF10279.9 OIR56817.1 - 0.11 13.0 4.2 0.17 12.3 4.2 1.4 1 1 0 1 1 1 0 Latarcin precursor Actin PF00022.19 OIR56818.1 - 8.2e-53 179.5 0.3 1.8e-27 96.0 0.0 2.4 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OIR56818.1 - 0.00056 18.8 0.2 0.0028 16.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 OIR56818.1 - 0.03 13.4 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; SPT16 PF08644.11 OIR56818.1 - 0.031 14.5 0.8 0.031 14.5 0.8 3.2 3 1 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) DUF1515 PF07439.11 OIR56818.1 - 0.064 13.3 0.3 0.22 11.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3040 PF11239.8 OIR56818.1 - 0.21 11.9 0.2 0.61 10.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Gemin6 PF06372.12 OIR56818.1 - 4.2 6.9 5.4 1.3 8.5 1.1 2.3 3 0 0 3 3 3 0 Gemin6 protein AAL_decarboxy PF03306.13 OIR56819.1 - 0.023 14.0 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase AgrB PF04647.15 OIR56819.1 - 0.037 13.3 0.4 0.06 12.6 0.4 1.4 1 1 0 1 1 1 0 Accessory gene regulator B RELT PF12606.8 OIR56819.1 - 1.8 7.6 5.1 15 4.7 0.4 3.1 3 0 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 PI3_PI4_kinase PF00454.27 OIR56820.1 - 1e-25 91.0 0.0 1.9e-24 86.8 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OIR56820.1 - 0.005 16.3 1.9 0.011 15.1 0.5 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Nucleic_acid_bd PF13820.6 OIR56821.1 - 0.0044 16.9 12.7 4.9 7.0 0.2 6.0 4 2 2 6 6 6 2 Putative nucleic acid-binding region Terminase_5 PF06056.12 OIR56821.1 - 0.12 12.3 0.5 10 6.1 0.0 3.7 5 0 0 5 5 5 0 Putative ATPase subunit of terminase (gpP-like) ANAPC15 PF15243.6 OIR56821.1 - 0.18 12.2 15.1 0.46 10.9 0.1 5.4 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 15 Sep15_SelM PF08806.11 OIR56821.1 - 0.96 9.7 15.5 0.3 11.3 0.4 4.9 7 0 0 7 7 7 0 Sep15/SelM redox domain zf-C3HC4_3 PF13920.6 OIR56822.1 - 0.0058 16.5 8.5 0.011 15.6 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OIR56822.1 - 0.0089 16.1 0.1 16 6.1 0.0 3.4 3 0 0 3 3 3 2 Two component regulator propeller TnpV PF14198.6 OIR56822.1 - 0.11 12.4 0.6 3.1 7.8 0.1 3.0 2 1 0 2 2 2 0 Transposon-encoded protein TnpV Prok-RING_4 PF14447.6 OIR56822.1 - 0.23 11.3 8.5 0.44 10.5 8.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OIR56822.1 - 2.6 8.1 10.0 8.7 6.4 10.2 1.8 1 1 1 2 2 2 0 zinc-RING finger domain FYVE_2 PF02318.16 OIR56822.1 - 3 8.1 7.0 0.94 9.7 3.2 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger TnpV PF14198.6 OIR56823.1 - 0.00014 21.8 3.0 1.5 8.8 0.0 4.5 3 2 2 5 5 5 3 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR56823.1 - 0.00068 19.6 0.8 2.2 8.8 0.0 4.4 5 0 0 5 5 5 1 Two component regulator propeller Nuc_sug_transp PF04142.15 OIR56823.1 - 0.41 9.8 2.8 54 2.8 0.1 3.6 2 1 2 4 4 4 0 Nucleotide-sugar transporter zf-C3HC4_3 PF13920.6 OIR56824.1 - 3.8e-05 23.4 8.2 7.4e-05 22.5 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF5100 PF17029.5 OIR56824.1 - 0.029 14.2 0.3 0.095 12.6 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5100) zf-C3HC4_4 PF15227.6 OIR56824.1 - 0.57 10.4 4.4 0.46 10.7 1.8 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OIR56824.1 - 1.2 9.0 6.6 3.8 7.4 6.6 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 OIR56824.1 - 1.3 9.1 7.1 11 6.1 6.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4 PF00097.25 OIR56824.1 - 3.3 7.7 9.9 2.4 8.1 7.7 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.6 OIR56824.1 - 3.4 8.3 6.3 2.5 8.7 2.6 2.6 2 1 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.12 OIR56824.1 - 4.6 7.6 8.1 1 9.7 3.2 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Serpin PF00079.20 OIR56827.1 - 0.15 11.4 0.0 0.74 9.0 0.0 2.0 2 1 0 2 2 2 0 Serpin (serine protease inhibitor) Reg_prop PF07494.11 OIR56827.1 - 0.25 11.7 0.7 4.9 7.7 0.0 3.0 4 0 0 4 4 4 0 Two component regulator propeller NBD94 PF16830.5 OIR56827.1 - 0.47 10.9 4.9 10 6.6 0.1 2.8 3 1 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH zf-C3HC4_3 PF13920.6 OIR56828.1 - 5.5e-05 22.9 7.9 0.00014 21.6 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR56828.1 - 0.00079 19.2 6.6 0.0019 18.0 6.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OIR56828.1 - 0.002 18.2 5.0 0.004 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 OIR56828.1 - 0.01 16.1 9.5 0.01 16.1 9.5 2.6 3 0 0 3 3 3 0 Ring finger domain FYVE_2 PF02318.16 OIR56828.1 - 0.021 15.0 5.9 0.048 13.9 5.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger zf-UDP PF14569.6 OIR56828.1 - 0.079 13.1 4.4 0.16 12.1 4.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 OIR56828.1 - 1.5 8.8 11.4 1.7 8.7 9.4 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OIR56828.1 - 5 7.1 12.4 5.5 7.0 10.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR56829.1 - 0.0011 18.8 7.2 0.0011 18.8 7.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR56829.1 - 0.0062 16.6 4.2 0.013 15.6 4.2 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Unpaired PF15972.5 OIR56829.1 - 0.06 12.9 1.7 3.7 7.0 0.2 3.5 4 0 0 4 4 4 0 Unpaired protein DUF3412 PF11892.8 OIR56829.1 - 0.14 12.3 0.5 1.3 9.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3412) Reg_prop PF07494.11 OIR56829.1 - 0.26 11.6 5.8 63 4.3 0.0 5.7 6 0 0 6 6 6 0 Two component regulator propeller DZR PF12773.7 OIR56829.1 - 1.4 9.1 4.3 5 7.2 4.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 OIR56830.1 - 0.0095 15.8 8.2 0.016 15.1 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 OIR56830.1 - 0.033 14.2 0.8 0.033 14.2 0.8 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PolC_DP2 PF03833.13 OIR56830.1 - 0.037 11.9 4.4 0.044 11.7 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Anti-TRAP PF15777.5 OIR56830.1 - 0.045 13.7 0.4 0.045 13.7 0.4 2.3 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein PHD PF00628.29 OIR56830.1 - 0.081 12.8 11.1 0.13 12.2 11.1 1.3 1 0 0 1 1 1 0 PHD-finger zinc-ribbons_6 PF07191.12 OIR56830.1 - 0.21 11.6 8.8 2.7 8.1 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-C2HC5 PF06221.13 OIR56830.1 - 2 8.5 12.0 1.8 8.6 4.0 2.8 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 OIR56830.1 - 5 6.7 10.7 8.9 5.9 0.2 3.2 2 1 1 3 3 3 0 zinc-ribbon domain HSM3_C PF18794.1 OIR56832.1 - 0.063 12.9 0.2 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, C terminal domain RnlA_toxin PF15935.5 OIR56832.1 - 0.079 12.7 0.8 3.9 7.2 0.0 2.9 1 1 2 3 3 3 0 RNase LS, bacterial toxin PhdYeFM_antitox PF02604.19 OIR56832.1 - 0.086 12.7 0.4 0.31 10.9 0.1 2.2 2 1 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DEAD PF00270.29 OIR56833.1 - 1.3e-30 106.5 0.2 2.8e-30 105.4 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR56833.1 - 2.6e-26 92.2 0.0 7.7e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR56833.1 - 0.0022 18.0 0.0 0.0022 18.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 OIR56833.1 - 0.034 12.9 0.0 6.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 zf-RVT PF13966.6 OIR56834.1 - 0.0063 17.2 0.1 0.011 16.5 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HEAT PF02985.22 OIR56835.1 - 5.9e-07 29.2 8.0 1.3 9.5 0.0 7.0 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 OIR56835.1 - 0.00039 20.7 7.4 0.071 13.5 0.0 5.8 6 1 0 6 6 6 1 HEAT repeats Cnd1 PF12717.7 OIR56835.1 - 0.0029 17.6 0.9 0.48 10.5 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OIR56835.1 - 0.0074 14.9 3.1 0.022 13.3 0.4 2.3 2 0 0 2 2 2 1 Adaptin N terminal region RNA_polI_A34 PF08208.11 OIR56835.1 - 1.9 8.5 9.4 32 4.5 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 TF_Zn_Ribbon PF08271.12 OIR56837.1 - 0.03 13.8 0.5 0.03 13.8 0.5 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2777 PF10949.8 OIR56837.1 - 0.12 12.0 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2777) XPG_I PF00867.18 OIR56838.1 - 9.3e-18 64.4 0.1 1.9e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OIR56838.1 - 4.9e-08 33.4 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain C1_2 PF03107.16 OIR56839.1 - 0.0035 17.6 1.2 0.0086 16.4 1.2 1.6 1 0 0 1 1 1 1 C1 domain Prok-RING_4 PF14447.6 OIR56839.1 - 0.033 14.0 6.7 0.075 12.9 6.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 OIR56839.1 - 0.04 14.0 1.8 0.12 12.5 1.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 OIR56839.1 - 0.058 13.3 6.2 0.12 12.2 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ProRS-C_1 PF09180.11 OIR56839.1 - 0.13 12.5 0.2 3.4 8.0 0.0 3.0 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal zf-RING_2 PF13639.6 OIR56839.1 - 4.6 7.7 9.0 10 6.6 9.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 OIR56841.1 - 0.39 10.6 3.3 0.8 9.6 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TBPIP PF07106.13 OIR56843.1 - 5e-06 26.3 0.1 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 OIR56843.1 - 0.00011 22.2 3.1 0.00011 22.2 3.1 2.5 2 0 0 2 2 2 1 Leucine zipper with capping helix domain MarR PF01047.22 OIR56843.1 - 0.05 13.5 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 MarR family TFIIE_beta PF02186.15 OIR56843.1 - 0.11 12.8 0.3 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 TFIIE beta subunit core domain DTHCT PF08070.11 OIR56843.1 - 1.1 10.1 20.8 0.11 13.3 12.3 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF1075 PF06388.11 OIR56843.1 - 3.6 7.6 11.8 0.15 12.1 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) HTH_3 PF01381.22 OIR56845.1 - 8.6e-11 41.7 0.9 1.2e-10 41.3 0.9 1.2 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OIR56845.1 - 2.4e-06 27.8 0.0 3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OIR56845.1 - 0.0011 18.9 0.4 0.0019 18.2 0.4 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 OIR56845.1 - 0.0072 16.4 0.0 0.008 16.3 0.0 1.1 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA BAR_2 PF10455.9 OIR56845.1 - 0.02 14.1 0.3 0.022 13.9 0.3 1.0 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking HTH_25 PF13413.6 OIR56845.1 - 0.083 12.8 0.2 0.16 11.8 0.2 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 OIR56845.1 - 0.09 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HR1 PF02185.16 OIR56845.1 - 0.86 9.8 4.9 0.15 12.2 0.4 1.9 2 0 0 2 2 2 0 Hr1 repeat MCM PF00493.23 OIR56846.1 - 2.7e-98 327.6 0.1 5.3e-98 326.6 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 OIR56846.1 - 2.3e-27 95.2 0.6 5.6e-27 94.0 0.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OIR56846.1 - 2.6e-27 95.1 2.0 5e-27 94.2 2.0 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 OIR56846.1 - 8.9e-09 35.0 0.1 3.2e-06 26.7 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 OIR56846.1 - 7.6e-08 32.9 0.0 2.6e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OIR56846.1 - 0.00011 22.2 0.0 0.00041 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OIR56846.1 - 0.003 17.3 0.1 0.016 14.9 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OIR56846.1 - 0.0084 16.0 0.0 0.034 14.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 OIR56846.1 - 0.17 12.5 0.9 0.95 10.1 0.6 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal ATPgrasp_N PF18130.1 OIR56846.1 - 0.32 11.6 1.8 7.1 7.3 0.4 3.3 3 1 0 3 3 3 0 ATP-grasp N-terminal domain AAA_11 PF13086.6 OIR56849.1 - 0.0068 16.2 0.0 0.0087 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OIR56849.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF1262 PF06880.11 OIR56850.1 - 0.046 14.1 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) DUF4382 PF14321.6 OIR56851.1 - 0.0011 19.3 0.0 0.34 11.2 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4382) PAC3 PF10178.9 OIR56851.1 - 0.022 14.9 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 RNA_pol_Rpb4 PF03874.16 OIR56851.1 - 0.061 13.7 3.1 0.4 11.0 0.2 2.9 2 2 0 2 2 2 0 RNA polymerase Rpb4 U3_assoc_6 PF08640.11 OIR56853.1 - 9.7e-12 44.8 6.3 2.8e-11 43.3 4.4 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 OIR56853.1 - 5e-08 33.1 0.1 0.28 12.1 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 OIR56853.1 - 0.00021 20.5 0.4 0.29 10.2 0.1 2.1 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 OIR56853.1 - 0.01 16.3 0.0 6.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat APG6_N PF17675.1 OIR56854.1 - 0.00015 22.3 9.9 0.00017 22.2 9.9 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Macoilin PF09726.9 OIR56854.1 - 0.00044 19.0 3.3 0.00045 18.9 3.3 1.0 1 0 0 1 1 1 1 Macoilin family PikAIV_N PF18605.1 OIR56854.1 - 0.0092 15.5 4.7 0.019 14.5 4.7 1.6 1 0 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Gastrin PF00918.17 OIR56854.1 - 0.025 15.6 1.4 0.029 15.3 1.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF3381 PF11861.8 OIR56854.1 - 0.029 14.2 11.2 0.042 13.6 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AAA_11 PF13086.6 OIR56854.1 - 0.039 13.7 2.4 0.045 13.5 2.4 1.0 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 OIR56854.1 - 0.11 13.0 12.1 2.9 8.4 13.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Mgr1 PF08602.10 OIR56854.1 - 0.16 10.7 2.9 0.17 10.6 2.9 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Atg14 PF10186.9 OIR56854.1 - 0.2 10.7 9.5 0.26 10.4 9.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CpxA_peri PF16527.5 OIR56854.1 - 0.2 12.0 3.8 0.28 11.6 3.8 1.3 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain MctB PF11382.8 OIR56854.1 - 0.21 11.2 1.9 0.3 10.8 1.9 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB SpecificRecomb PF10136.9 OIR56854.1 - 0.22 9.8 1.0 0.25 9.6 1.0 1.0 1 0 0 1 1 1 0 Site-specific recombinase CENP-H PF05837.12 OIR56854.1 - 0.55 10.7 12.8 1 9.8 12.6 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.16 OIR56854.1 - 0.58 9.0 1.6 0.56 9.0 1.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein O-antigen_lig PF13425.6 OIR56854.1 - 0.6 8.8 1.4 0.63 8.8 1.4 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein zf-RING_2 PF13639.6 OIR56855.1 - 6.5e-07 29.6 7.0 2.1e-06 27.9 7.0 2.0 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OIR56855.1 - 1.3e-05 25.1 1.2 2.6e-05 24.2 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OIR56855.1 - 1.6e-05 25.1 5.9 8.4e-05 22.8 6.1 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 OIR56855.1 - 0.00028 21.0 3.5 0.0014 18.8 3.5 2.2 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OIR56855.1 - 0.0021 18.0 4.4 0.007 16.4 4.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OIR56855.1 - 0.0062 16.1 3.2 0.015 14.9 3.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 OIR56855.1 - 0.014 15.3 5.0 0.033 14.1 5.0 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 OIR56855.1 - 0.014 15.2 6.9 0.037 13.9 6.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR56855.1 - 0.023 14.6 6.7 0.06 13.2 6.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PrmC_N PF17827.1 OIR56855.1 - 0.062 13.9 0.1 0.56 10.8 0.0 2.5 2 0 0 2 2 2 0 PrmC N-terminal domain zf-C3HC4_3 PF13920.6 OIR56855.1 - 0.16 11.9 5.3 0.44 10.4 5.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR56855.1 - 0.2 11.7 5.7 0.73 9.8 5.7 2.1 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 OIR56855.1 - 0.32 11.3 5.8 1.2 9.5 6.0 1.9 1 1 0 1 1 1 0 RING-like domain zf-UDP PF14569.6 OIR56855.1 - 0.34 11.1 3.2 0.9 9.7 3.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 OIR56855.1 - 0.72 10.1 5.0 5.6 7.2 5.0 2.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 OIR56855.1 - 2.1 8.6 11.6 0.13 12.4 5.0 2.3 2 0 0 2 2 2 0 RING-variant domain Prok-RING_4 PF14447.6 OIR56855.1 - 3.9 7.4 8.6 0.81 9.6 0.9 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR56855.1 - 6.5 6.6 11.1 0.82 9.5 6.7 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Ribosomal_L18A PF01775.17 OIR56862.1 - 1.1e-28 99.7 5.6 1.1e-28 99.7 5.6 1.3 2 0 0 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_L19e PF01280.20 OIR56863.1 - 2.1e-50 170.5 11.1 2.6e-50 170.2 11.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e HTH_24 PF13412.6 OIR56863.1 - 0.036 13.6 3.1 3.4 7.3 0.1 3.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Siva PF05458.12 OIR56863.1 - 0.06 13.0 0.2 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Tho2 PF11262.8 OIR56863.1 - 0.37 10.0 5.5 0.54 9.4 5.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TssO PF17561.2 OIR56864.1 - 0.046 13.8 4.7 0.32 11.1 3.5 2.8 2 1 0 2 2 2 0 Type VI secretion system, TssO ACP_PD PF04336.12 OIR56864.1 - 2.5 8.6 6.7 0.76 10.2 0.1 3.1 4 1 0 4 4 4 0 Acyl carrier protein phosphodiesterase Metalloenzyme PF01676.18 OIR56866.1 - 1.2e-72 244.3 0.1 1.3e-72 244.1 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 OIR56866.1 - 3.2e-63 213.0 0.0 4.4e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 OIR56866.1 - 6.1e-06 26.1 0.0 9.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5092 PF17010.5 OIR56870.1 - 2.2e-23 83.0 2.6 1.3e-17 64.2 0.6 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5092) DUF2207 PF09972.9 OIR56870.1 - 0.14 10.9 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) YwiC PF14256.6 OIR56870.1 - 0.17 12.2 2.0 0.38 11.1 2.0 1.6 1 0 0 1 1 1 0 YwiC-like protein ABC_membrane PF00664.23 OIR56871.1 - 1.8e-06 27.8 2.2 2.7e-06 27.2 2.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region Methyltr_RsmB-F PF01189.17 OIR56874.1 - 7.8e-21 74.6 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OIR56874.1 - 0.0019 18.7 0.1 0.0097 16.4 0.1 2.1 1 1 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OIR56874.1 - 0.037 14.1 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MAJIN PF15077.6 OIR56875.1 - 0.54 10.0 11.0 0.67 9.7 11.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Presenilin PF01080.17 OIR56875.1 - 0.87 8.3 15.0 0.96 8.1 15.0 1.0 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.12 OIR56875.1 - 1.4 8.2 10.4 1.8 7.9 10.4 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger BUD22 PF09073.10 OIR56875.1 - 1.5 8.0 37.5 1.7 7.9 37.5 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OIR56875.1 - 1.7 8.0 34.1 1.9 7.8 34.1 1.0 1 0 0 1 1 1 0 SDA1 FAM60A PF15396.6 OIR56875.1 - 2.4 8.1 9.8 3.2 7.7 9.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A NARP1 PF12569.8 OIR56875.1 - 2.5 6.9 8.8 3 6.6 8.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PPP4R2 PF09184.11 OIR56875.1 - 3 7.3 26.5 3.3 7.2 26.5 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OIR56875.1 - 4.3 5.4 29.9 4.6 5.3 29.9 1.0 1 0 0 1 1 1 0 Nop14-like family V_ATPase_I PF01496.19 OIR56875.1 - 7.9 4.3 6.3 8.7 4.1 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NOP19 PF10863.8 OIR56877.1 - 0.06 13.2 0.2 0.081 12.8 0.2 1.2 1 0 0 1 1 1 0 Nucleolar protein 19 Reg_prop PF07494.11 OIR56879.1 - 0.00029 20.7 0.2 43 4.8 0.0 5.4 5 0 0 5 5 5 0 Two component regulator propeller BAF250_C PF12031.8 OIR56879.1 - 0.014 14.7 2.5 7.4 5.8 0.0 4.4 3 3 3 6 6 6 0 SWI/SNF-like complex subunit BAF250/Osa Sep15_SelM PF08806.11 OIR56879.1 - 0.014 15.5 11.8 8.5 6.6 0.1 5.5 5 2 1 6 6 6 0 Sep15/SelM redox domain Nuc_sug_transp PF04142.15 OIR56879.1 - 0.023 13.9 6.6 13 4.9 0.2 4.8 5 1 1 6 6 6 0 Nucleotide-sugar transporter TnpV PF14198.6 OIR56879.1 - 0.047 13.7 17.3 2.7 8.0 1.3 6.5 5 2 1 6 6 6 0 Transposon-encoded protein TnpV DUF2316 PF10078.9 OIR56879.1 - 0.065 13.5 1.7 13 6.1 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Nucleic_acid_bd PF13820.6 OIR56879.1 - 0.069 13.0 5.8 52 3.7 0.0 5.3 6 0 0 6 6 6 0 Putative nucleic acid-binding region DUF1128 PF06569.11 OIR56879.1 - 0.24 11.4 4.3 35 4.5 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1128) DUF1213 PF06740.12 OIR56879.1 - 0.4 11.3 1.4 53 4.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1213) zf-C3HC4_3 PF13920.6 OIR56880.1 - 2.5e-05 24.0 5.0 5.5e-05 22.9 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BAF250_C PF12031.8 OIR56880.1 - 4.5e-05 22.9 1.3 7.2 5.8 0.0 5.7 5 2 1 7 7 7 1 SWI/SNF-like complex subunit BAF250/Osa Reg_prop PF07494.11 OIR56880.1 - 0.00055 19.9 10.8 36 5.1 0.1 8.6 11 0 0 11 11 11 0 Two component regulator propeller EIF_2_alpha PF07541.12 OIR56880.1 - 0.017 15.2 0.5 8 6.6 0.1 4.3 5 0 0 5 5 5 0 Eukaryotic translation initiation factor 2 alpha subunit zf-UDP PF14569.6 OIR56880.1 - 0.036 14.2 5.4 0.088 12.9 5.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Nucleic_acid_bd PF13820.6 OIR56880.1 - 0.043 13.7 5.8 27 4.6 0.0 6.1 8 0 0 8 8 8 0 Putative nucleic acid-binding region FYVE_2 PF02318.16 OIR56880.1 - 0.095 12.9 7.0 0.27 11.5 7.0 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger TnpV PF14198.6 OIR56880.1 - 0.18 11.8 10.1 21 5.1 0.0 5.5 5 0 0 5 5 5 0 Transposon-encoded protein TnpV Adeno_terminal PF02459.15 OIR56881.1 - 7.1 4.9 6.6 13 4.0 6.6 1.6 1 1 0 1 1 1 0 Adenoviral DNA terminal protein BAF250_C PF12031.8 OIR56883.1 - 0.00053 19.4 0.1 0.24 10.7 0.0 3.7 3 1 0 3 3 3 1 SWI/SNF-like complex subunit BAF250/Osa zf-C3HC4_3 PF13920.6 OIR56883.1 - 0.00069 19.4 7.2 0.0015 18.3 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TnpV PF14198.6 OIR56883.1 - 0.011 15.7 18.7 0.24 11.4 0.1 7.2 2 2 5 7 7 7 0 Transposon-encoded protein TnpV Prok-RING_4 PF14447.6 OIR56883.1 - 0.016 15.1 7.0 0.033 14.1 7.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Inp1 PF12634.7 OIR56883.1 - 0.022 14.8 0.5 0.27 11.3 0.1 2.9 2 2 0 2 2 2 0 Inheritance of peroxisomes protein 1 zf-RING_10 PF16685.5 OIR56883.1 - 1.1 9.4 4.7 2.7 8.2 4.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Stc1 PF12898.7 OIR56883.1 - 3.4 8.3 9.0 0.77 10.4 4.8 1.9 1 1 1 2 2 2 0 Stc1 domain TnpV PF14198.6 OIR56884.1 - 3.6e-05 23.7 4.5 1.1 9.3 0.3 4.8 1 1 2 3 3 3 3 Transposon-encoded protein TnpV zf-C3HC4_3 PF13920.6 OIR56884.1 - 8.4e-05 22.3 6.9 0.0002 21.2 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OIR56884.1 - 0.00077 19.4 0.2 39 5.0 0.0 4.4 4 0 0 4 4 4 0 Two component regulator propeller zf-UDP PF14569.6 OIR56884.1 - 0.0062 16.6 4.8 0.015 15.4 4.8 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger Nucleic_acid_bd PF13820.6 OIR56884.1 - 0.022 14.6 1.0 10 5.9 0.0 3.7 3 0 0 3 3 3 0 Putative nucleic acid-binding region Cys_rich_KTR PF14205.6 OIR56884.1 - 0.039 13.8 0.1 0.56 10.1 0.1 2.9 2 0 0 2 2 2 0 Cysteine-rich KTR zf-RING_2 PF13639.6 OIR56884.1 - 0.059 13.7 7.7 0.19 12.1 7.7 1.8 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OIR56884.1 - 0.98 9.3 5.0 3.7 7.5 5.1 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RecR PF02132.15 OIR56884.1 - 1.1 8.9 4.6 0.23 11.1 0.4 2.1 2 0 0 2 2 2 0 RecR protein zf-RING_4 PF14570.6 OIR56884.1 - 1.5 8.7 6.5 17 5.3 6.5 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ANAPC15 PF15243.6 OIR56884.1 - 7.3 7.1 9.7 20 5.6 0.1 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 15 zf-C3HC4 PF00097.25 OIR56884.1 - 8.1 6.4 6.9 28 4.7 6.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR56885.1 - 0.00057 19.7 7.2 0.0011 18.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.12 OIR56885.1 - 0.087 13.3 6.5 0.16 12.5 6.5 1.4 1 0 0 1 1 1 0 CHY zinc finger FYVE_2 PF02318.16 OIR56885.1 - 0.15 12.3 8.2 0.32 11.2 8.2 1.5 1 1 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 OIR56885.1 - 0.22 11.4 7.9 0.26 11.2 6.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Elf1 PF05129.13 OIR56885.1 - 2.3 8.3 9.5 1.4 9.0 6.4 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 OIR56885.1 - 4 7.5 8.3 14 5.8 7.1 2.1 1 1 1 2 2 2 0 Double zinc ribbon Stc1 PF12898.7 OIR56885.1 - 5.3 7.7 9.1 3.3 8.3 5.3 2.1 1 1 1 2 2 2 0 Stc1 domain zf-C3HC4 PF00097.25 OIR56885.1 - 5.9 6.8 9.2 13 5.8 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 OIR56886.1 - 9.3e-05 22.7 0.1 16 5.8 0.0 4.6 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OIR56886.1 - 0.00026 21.7 0.8 5.5 8.0 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat DCAF17 PF15802.5 OIR56886.1 - 0.01 14.6 0.0 7.4 5.1 0.0 3.0 2 1 1 3 3 3 2 DDB1- and CUL4-associated factor 17 GCP_C_terminal PF04130.13 OIR56888.1 - 1.5e-43 149.4 0.1 2.8e-43 148.6 0.0 1.4 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OIR56888.1 - 1.6e-34 120.0 0.0 2.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal CTD_bind PF04818.13 OIR56889.1 - 5.5e-07 30.3 0.0 1.5e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. BIR PF00653.21 OIR56889.1 - 0.88 10.3 5.4 4.7 7.9 1.5 2.5 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain RIBIOP_C PF04950.12 OIR56892.1 - 1.7e-46 159.0 0.0 3.8e-46 157.8 0.0 1.5 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PapC_C PF13953.6 OIR56892.1 - 0.14 12.0 0.1 0.51 10.2 0.1 1.9 1 0 0 1 1 1 0 PapC C-terminal domain D5_N PF08706.11 OIR56892.1 - 4.5 7.5 5.3 4.3 7.6 0.0 2.8 3 0 0 3 3 3 0 D5 N terminal like DUF3440 PF11922.8 OIR56893.1 - 0.052 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) IF4E PF01652.18 OIR56893.1 - 0.096 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E Methyltransf_11 PF08241.12 OIR56895.1 - 3.4e-10 40.4 0.0 5.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OIR56895.1 - 1.8e-06 28.5 0.0 4.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OIR56895.1 - 0.00017 21.4 0.1 0.0087 15.9 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OIR56895.1 - 0.031 15.0 0.0 0.73 10.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 OIR56895.1 - 0.15 11.6 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF2515 PF10720.9 OIR56896.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) RVT_1 PF00078.27 OIR56897.1 - 7.7e-41 140.0 0.0 9.8e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cse1 PF08506.10 OIR56898.1 - 2.3e-87 293.2 0.0 3.5e-87 292.6 0.0 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 OIR56898.1 - 3.2e-60 203.9 1.6 2e-59 201.3 1.2 2.4 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 OIR56898.1 - 2e-09 37.2 0.0 4e-08 33.1 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF1242 PF06842.12 OIR56898.1 - 0.035 13.9 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) UME PF08064.13 OIR56898.1 - 0.099 12.6 3.6 0.48 10.4 0.2 3.2 3 0 0 3 3 3 0 UME (NUC010) domain GDI PF00996.18 OIR56899.1 - 6.8e-159 529.0 0.0 8.2e-159 528.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Coatomer_WDAD PF04053.14 OIR56901.1 - 4.8e-94 315.9 0.0 1.8e-92 310.7 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.32 OIR56901.1 - 9.1e-32 108.6 16.7 2.5e-06 28.1 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat WD40_like PF17005.5 OIR56901.1 - 0.00017 21.0 0.2 0.03 13.6 0.0 2.5 1 1 1 2 2 2 2 WD40-like domain GPP34 PF05719.11 OIR56902.1 - 3.6e-36 125.1 0.1 4.6e-36 124.8 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) LSM PF01423.22 OIR56903.1 - 1.1e-11 44.3 0.1 1.8e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OIR56903.1 - 0.058 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain ATP-synt_C PF00137.21 OIR56904.1 - 2.3e-19 69.5 18.2 5e-10 39.6 9.7 2.5 2 0 0 2 2 2 2 ATP synthase subunit C DUF5510 PF17629.2 OIR56904.1 - 5.4 7.0 8.2 0.78 9.7 2.4 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5510) Cad PF03596.13 OIR56905.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Cadmium resistance transporter RVT_1 PF00078.27 OIR56906.1 - 1.2e-32 113.2 0.0 2.3e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OIR56906.1 - 6e-29 100.0 0.0 2.6e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OIR56906.1 - 1.1e-26 93.1 0.0 4.1e-26 91.3 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OIR56906.1 - 1.2e-22 80.3 0.0 2.7e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OIR56906.1 - 1.2e-15 57.4 0.5 2.3e-15 56.4 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OIR56906.1 - 2e-13 50.7 0.0 5.8e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OIR56906.1 - 4.9e-13 49.5 0.0 1.6e-12 47.9 0.0 1.9 2 0 0 2 2 1 1 Aspartyl protease RVP_2 PF08284.11 OIR56906.1 - 1.4e-11 44.4 0.0 3.4e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OIR56906.1 - 2.6e-08 34.0 0.1 1.3e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.10 OIR56906.1 - 4.6e-08 33.1 0.8 1.1e-07 31.9 0.8 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Peptidase_A3 PF02160.15 OIR56906.1 - 1.8e-05 24.3 0.2 3.6e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) zf-CCHC PF00098.23 OIR56906.1 - 2.5e-05 24.1 1.1 5.1e-05 23.2 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle DDE_Tnp_IS1595 PF12762.7 OIR56906.1 - 0.00021 21.3 0.0 0.0016 18.5 0.0 2.2 2 0 0 2 2 2 1 ISXO2-like transposase domain Asp_protease PF09668.10 OIR56906.1 - 0.0029 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DDE_3 PF13358.6 OIR56906.1 - 0.0096 15.7 0.0 0.055 13.2 0.0 2.2 3 0 0 3 3 2 1 DDE superfamily endonuclease rve_3 PF13683.6 OIR56906.1 - 0.015 15.1 0.1 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain HTH_22 PF13309.6 OIR56906.1 - 0.028 14.5 0.3 0.34 11.0 0.1 2.8 2 0 0 2 2 2 0 HTH domain MLVIN_C PF18697.1 OIR56906.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain HscB_4_cys PF18256.1 OIR56906.1 - 0.16 11.8 2.9 0.38 10.6 2.9 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif RNA_pol_Rpb1_1 PF04997.12 OIR56908.1 - 7.6e-97 324.4 0.0 1.1e-96 323.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OIR56908.1 - 7.2e-89 297.8 0.0 1.2e-88 297.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OIR56908.1 - 2.4e-69 232.8 0.1 4.5e-69 231.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OIR56908.1 - 8.6e-37 126.5 0.1 6.9e-36 123.6 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OIR56908.1 - 8.7e-35 118.9 0.4 1.8e-34 117.9 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 OIR56908.1 - 4.6e-23 81.7 0.0 1.5e-22 80.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_6 PF04992.14 OIR56908.1 - 7e-18 65.1 0.0 2.1e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_R PF05001.13 OIR56908.1 - 1.4e-07 31.5 91.8 0.066 13.6 11.5 6.8 6 0 0 6 6 6 5 RNA polymerase Rpb1 C-terminal repeat Ribosomal_L26 PF16906.5 OIR56909.1 - 5e-28 97.4 3.2 6e-28 97.1 3.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OIR56909.1 - 0.00033 20.5 0.7 0.00054 19.8 0.7 1.3 1 0 0 1 1 1 1 KOW motif DUF2895 PF11444.8 OIR56909.1 - 0.066 12.6 0.2 0.094 12.1 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2895) TnpV PF14198.6 OIR56910.1 - 6.9e-07 29.2 10.8 0.083 12.9 0.4 5.1 2 1 3 5 5 5 3 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR56910.1 - 8.9e-06 25.3 0.1 16 6.2 0.0 5.4 5 1 0 5 5 5 1 Two component regulator propeller ANAPC15 PF15243.6 OIR56910.1 - 0.0059 17.0 11.0 7.4 7.1 0.1 5.0 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 15 Lectin_C PF00059.21 OIR56910.1 - 0.0075 17.0 1.6 93 3.8 0.0 4.5 5 0 0 5 5 5 0 Lectin C-type domain MlaD PF02470.20 OIR56910.1 - 0.028 14.7 0.0 16 5.9 0.0 3.6 2 1 2 4 4 4 0 MlaD protein Helicase_PWI PF18149.1 OIR56910.1 - 0.039 14.1 2.6 0.18 12.0 0.4 2.5 2 1 0 2 2 2 0 N-terminal helicase PWI domain Nucleic_acid_bd PF13820.6 OIR56910.1 - 0.13 12.1 9.1 9.2 6.1 0.4 4.3 4 1 1 5 5 5 0 Putative nucleic acid-binding region DUF2573 PF10835.8 OIR56910.1 - 0.32 11.4 3.9 20 5.6 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2573) Sep15_SelM PF08806.11 OIR56910.1 - 1.9 8.7 6.3 1.2 9.3 0.1 3.4 5 0 0 5 5 5 0 Sep15/SelM redox domain DUF2316 PF10078.9 OIR56910.1 - 2.9 8.2 6.5 14 6.0 0.1 3.7 4 2 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2316) Nuc_sug_transp PF04142.15 OIR56910.1 - 7.8 5.6 12.4 14 4.7 0.1 4.5 3 2 1 5 5 5 0 Nucleotide-sugar transporter Zn_Tnp_IS1 PF03811.13 OIR56911.1 - 0.0028 17.3 0.1 0.0082 15.8 0.1 1.7 1 0 0 1 1 1 1 InsA N-terminal domain PhnA_Zn_Ribbon PF08274.12 OIR56911.1 - 0.066 13.2 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Exonuc_VII_L PF02601.15 OIR56912.1 - 2 7.9 5.6 22 4.5 6.8 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit cNMP_binding PF00027.29 OIR56915.1 - 8.1e-19 67.5 0.1 2.8e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain LRR_6 PF13516.6 OIR56915.1 - 1.5 9.0 11.9 14 6.0 0.0 5.7 7 0 0 7 7 7 0 Leucine Rich repeat Helicase_C PF00271.31 OIR56916.1 - 7.2e-16 58.5 0.1 1.4e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YacG PF03884.14 OIR56918.1 - 5.6e-08 32.4 0.0 1.8 8.4 0.0 5.3 5 0 0 5 5 5 3 DNA gyrase inhibitor YacG NikR_C PF08753.11 OIR56918.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 NikR C terminal nickel binding domain DUF2001 PF09393.10 OIR56918.1 - 0.029 14.4 0.4 14 5.7 0.0 3.6 4 0 0 4 4 4 0 Phage tail tube protein RE_EcoO109I PF14511.6 OIR56918.1 - 0.035 13.7 0.0 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 Type II restriction endonuclease EcoO109I Cpn60_TCP1 PF00118.24 OIR56920.1 - 1.1e-148 495.9 6.2 1.3e-148 495.7 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1040 PF06288.13 OIR56921.1 - 0.098 13.1 0.3 0.31 11.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) zf-UDP PF14569.6 OIR56922.1 - 2.2e-05 24.5 3.2 5.6e-05 23.2 3.2 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OIR56922.1 - 0.0026 17.6 2.2 0.0086 15.9 2.2 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OIR56922.1 - 0.01 15.7 5.1 0.02 14.7 5.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2110 PF09883.9 OIR56922.1 - 0.027 14.1 0.1 5.4 6.5 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) zf-RING_2 PF13639.6 OIR56922.1 - 0.084 13.2 6.9 0.19 12.1 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 OIR56922.1 - 0.12 12.7 2.8 0.33 11.3 2.8 1.7 1 0 0 1 1 1 0 C1 domain Thump_like PF18096.1 OIR56922.1 - 0.14 12.1 0.8 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 THUMP domain-like Blo-t-5 PF11642.8 OIR56922.1 - 1.3 9.0 8.3 0.8 9.7 2.4 2.7 2 0 0 2 2 2 0 Mite allergen Blo t 5 VID27 PF08553.10 OIR56923.1 - 1.1e-118 396.4 0.1 1.8e-118 395.7 0.1 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 OIR56923.1 - 1.9e-11 44.2 0.3 3.7e-11 43.3 0.3 1.5 1 0 0 1 1 1 1 VID27 PH-like domain Smg4_UPF3 PF03467.15 OIR56923.1 - 0.0014 18.7 2.1 0.0024 17.9 2.1 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family HEPN_AbiV PF18728.1 OIR56923.1 - 0.0094 16.1 1.5 0.022 14.9 1.5 1.5 1 0 0 1 1 1 1 AbiV SspB PF04386.13 OIR56923.1 - 0.095 12.6 1.6 0.24 11.3 1.6 1.6 1 0 0 1 1 1 0 Stringent starvation protein B NOA36 PF06524.12 OIR56923.1 - 1.1 8.5 7.0 2.2 7.6 7.0 1.3 1 0 0 1 1 1 0 NOA36 protein PBP_sp32 PF07222.12 OIR56923.1 - 6.8 6.1 7.7 11 5.4 7.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 XPG_I PF00867.18 OIR56924.1 - 5.7e-24 84.3 2.0 6.8e-24 84.1 0.3 1.9 1 1 1 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 OIR56924.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing zf-UDP PF14569.6 OIR56925.1 - 0.0011 19.1 3.8 0.0025 17.9 3.8 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 OIR56925.1 - 0.0014 18.4 2.4 0.0043 16.9 2.4 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OIR56925.1 - 0.015 15.2 5.1 0.033 14.1 5.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 OIR56925.1 - 0.053 13.8 1.8 0.16 12.4 1.8 1.8 1 0 0 1 1 1 0 C1 domain zf-RING_2 PF13639.6 OIR56925.1 - 0.19 12.1 6.8 0.43 11.0 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 OIR56925.1 - 4 7.4 7.1 10 6.1 7.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4891 PF16232.5 OIR56931.1 - 0.13 12.8 0.2 11 6.6 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4891) zf-C3HC4_3 PF13920.6 OIR56932.1 - 0.29 11.0 4.4 0.62 10.0 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_S51 PF03575.17 OIR56933.1 - 0.019 14.6 0.0 0.76 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S51 zf-C3HC4_3 PF13920.6 OIR56933.1 - 0.17 11.7 3.3 0.31 10.9 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) rve PF00665.26 OIR56934.1 - 1.9e-14 53.9 0.0 3.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR56934.1 - 0.00039 20.1 0.1 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RRM_2 PF04059.12 OIR56935.1 - 1.3e-39 134.3 1.2 1.8e-39 133.9 1.2 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 OIR56935.1 - 0.00084 19.1 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OIR56935.1 - 0.0075 16.5 0.3 0.011 15.9 0.3 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 SEP PF08059.13 OIR56937.1 - 1.2e-18 67.4 0.2 3e-18 66.2 0.2 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OIR56937.1 - 2e-08 34.3 0.2 3.5e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 UBX domain DUF2840 PF11000.8 OIR56937.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) Adhes-Ig_like PF09085.10 OIR56938.1 - 0.022 14.9 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like dCMP_cyt_deam_1 PF00383.23 OIR56939.1 - 1.1e-06 28.4 0.4 1.8e-06 27.7 0.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OIR56939.1 - 0.0044 16.8 0.3 0.0064 16.3 0.3 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Rieske_3 PF18465.1 OIR56939.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Rieske 3Fe-4S SpoIIAA-like PF11964.8 OIR56939.1 - 0.039 15.0 0.2 9.8 7.3 0.0 2.4 2 0 0 2 2 2 0 SpoIIAA-like MAGE PF01454.19 OIR56940.1 - 1.1e-19 71.0 2.1 5.7e-19 68.7 2.1 2.0 1 1 0 1 1 1 1 MAGE family Ocnus PF05005.15 OIR56940.1 - 0.047 13.8 0.3 0.8 9.9 0.0 2.3 2 1 0 2 2 2 0 Janus/Ocnus family (Ocnus) Hydrolase_4 PF12146.8 OIR56941.1 - 3.2e-13 49.5 0.0 3.3e-12 46.2 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OIR56941.1 - 0.00027 21.6 0.0 0.00035 21.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OIR56941.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TFCD_C PF12612.8 OIR56942.1 - 0.038 13.8 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal O-FucT PF10250.9 OIR56943.1 - 8.6e-20 71.7 2.8 1.4e-18 67.8 0.9 2.9 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase DUF563 PF04577.14 OIR56943.1 - 3.7e-15 56.6 0.0 7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Brix PF04427.18 OIR56944.1 - 2.5e-31 109.3 0.3 2.5e-31 109.3 0.3 1.5 2 0 0 2 2 2 1 Brix domain AviRa PF11599.8 OIR56944.1 - 0.071 12.6 0.1 0.29 10.5 0.2 1.8 2 0 0 2 2 2 0 RRNA methyltransferase AviRa DUF4519 PF15012.6 OIR56944.1 - 1 9.6 6.4 20 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) AAA PF00004.29 OIR56945.1 - 5.4e-12 46.3 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OIR56945.1 - 3.7e-06 27.1 0.1 0.00019 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OIR56945.1 - 5.3e-06 26.8 0.1 0.00049 20.4 0.1 2.6 1 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 OIR56945.1 - 1.8e-05 24.8 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 OIR56945.1 - 4e-05 23.4 0.0 6.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OIR56945.1 - 7.9e-05 23.2 0.1 0.00036 21.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OIR56945.1 - 0.00017 22.0 0.1 0.00036 20.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OIR56945.1 - 0.00048 19.5 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.14 OIR56945.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OIR56945.1 - 0.0038 17.0 0.0 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OIR56945.1 - 0.0056 16.3 0.8 0.044 13.3 0.1 2.6 3 1 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 OIR56945.1 - 0.0087 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 OIR56945.1 - 0.01 16.1 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OIR56945.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OIR56945.1 - 0.014 15.1 0.0 0.087 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OIR56945.1 - 0.02 15.4 2.0 0.045 14.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OIR56945.1 - 0.032 14.1 0.4 0.13 12.1 0.0 2.2 3 0 0 3 3 3 0 NTPase TniB PF05621.11 OIR56945.1 - 0.047 13.1 0.1 9.3 5.6 0.0 2.7 2 1 1 3 3 3 0 Bacterial TniB protein Parvo_NS1 PF01057.17 OIR56945.1 - 0.054 12.6 0.0 0.17 10.9 0.0 1.8 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 OIR56945.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OIR56945.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 OIR56945.1 - 0.095 13.0 2.4 0.44 10.9 0.6 2.6 2 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OIR56945.1 - 0.097 12.2 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_14 PF13173.6 OIR56945.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OIR56945.1 - 0.13 12.7 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 OIR56945.1 - 0.15 11.9 0.0 0.38 10.7 0.0 1.6 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 OIR56945.1 - 0.16 11.8 0.8 0.46 10.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OIR56945.1 - 0.18 11.6 0.0 0.57 10.0 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain IF-2B PF01008.17 OIR56946.1 - 4.8e-10 39.1 0.1 1.5e-09 37.4 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family PSS PF03034.15 OIR56947.1 - 8.1e-95 317.7 9.6 1.1e-94 317.3 9.6 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase ICMT PF04140.14 OIR56948.1 - 2.6e-09 37.4 1.2 3.1e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OIR56948.1 - 2.2e-05 24.8 0.5 8.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ArsA_ATPase PF02374.15 OIR56950.1 - 2.6e-33 115.5 0.0 2.9e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OIR56950.1 - 6.2e-11 42.5 0.0 7.7e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OIR56950.1 - 8.1e-09 35.6 0.0 9.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OIR56950.1 - 3.9e-05 23.2 0.3 6.8e-05 22.4 0.3 1.3 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 OIR56950.1 - 0.00031 20.3 0.0 0.00033 20.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OIR56950.1 - 0.00065 19.4 0.2 0.0016 18.1 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 OIR56950.1 - 0.00098 18.7 0.0 0.0012 18.4 0.0 1.3 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 OIR56950.1 - 0.0012 19.3 0.0 0.0013 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 OIR56950.1 - 0.0019 17.4 0.1 0.0019 17.4 0.1 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 OIR56950.1 - 0.0023 17.6 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OIR56950.1 - 0.003 17.0 0.0 0.0032 17.0 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_18 PF13238.6 OIR56950.1 - 0.0043 17.6 0.0 0.0051 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF1611 PF07755.11 OIR56950.1 - 0.0069 15.7 0.0 0.0073 15.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1611_C) P-loop domain ATPase PF06745.13 OIR56950.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 KaiC Methyltransf_4 PF02390.17 OIR56950.1 - 0.023 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Zeta_toxin PF06414.12 OIR56950.1 - 0.025 13.9 0.0 0.035 13.4 0.0 1.2 1 1 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 OIR56950.1 - 0.03 14.1 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OIR56950.1 - 0.061 13.0 0.0 0.068 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OIR56950.1 - 0.073 12.2 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DnaB_C PF03796.15 OIR56950.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Prefoldin_2 PF01920.20 OIR56951.1 - 1.7e-08 34.4 4.2 2.1e-08 34.1 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 OIR56951.1 - 0.017 15.3 0.6 0.023 14.9 0.6 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF257 PF03192.13 OIR56951.1 - 0.031 14.1 0.9 0.033 14.0 0.9 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 WASH_WAHD PF11945.8 OIR56951.1 - 0.081 12.4 1.8 0.15 11.6 0.5 1.8 1 1 1 2 2 2 0 WAHD domain of WASH complex DUF1366 PF07104.11 OIR56951.1 - 0.096 12.4 1.7 6.6 6.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1366) Pkinase PF00069.25 OIR56952.1 - 1.2e-21 77.2 1.5 1.1e-19 70.8 1.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56952.1 - 4.1e-11 42.6 0.3 5.6e-11 42.2 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56952.1 - 3.5e-06 26.5 0.4 5.4e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OIR56952.1 - 0.00032 20.1 0.3 0.0059 16.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like TPR_12 PF13424.6 OIR56953.1 - 0.00011 22.4 0.2 0.024 14.9 0.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 OIR56953.1 - 0.00013 21.8 0.3 0.4 10.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OIR56953.1 - 0.00053 19.7 0.2 0.25 11.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OIR56953.1 - 0.0038 17.0 1.1 0.29 11.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 OIR56953.1 - 0.0086 16.6 0.0 0.7 10.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OIR56953.1 - 0.024 14.8 0.3 6.2 7.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 OIR56953.1 - 0.055 13.8 0.1 2.2 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OIR56953.1 - 0.096 13.1 0.0 0.65 10.5 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 OIR56953.1 - 0.26 12.0 1.0 51 4.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 OIR56954.1 - 1.3e-30 106.6 0.0 2e-29 102.8 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56954.1 - 2.3e-18 66.4 0.0 3.1e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56954.1 - 1.4e-07 31.1 0.9 6.9e-07 28.8 0.9 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR56954.1 - 2.8e-06 27.4 0.6 0.0021 18.0 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OIR56954.1 - 0.00044 19.3 0.2 0.00065 18.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 OIR56954.1 - 0.00063 19.4 0.2 0.0013 18.4 0.2 1.5 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 OIR56954.1 - 0.016 14.9 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 OIR56954.1 - 0.033 13.8 0.1 0.055 13.1 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 OIR56954.1 - 0.04 13.2 0.0 2.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like DUF4096 PF13340.6 OIR56954.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Pkinase PF00069.25 OIR56956.1 - 4.5e-21 75.4 0.8 1.4e-20 73.8 0.2 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56956.1 - 3.3e-11 43.0 0.1 4.8e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56956.1 - 0.00082 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR56956.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pam16 PF03656.13 OIR56957.1 - 0.035 14.1 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Pam16 DnaJ PF00226.31 OIR56957.1 - 0.064 13.4 0.1 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 DnaJ domain Ribosomal_S28e PF01200.18 OIR56959.1 - 7.2e-30 102.8 2.0 7.7e-30 102.7 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Nop52 PF05997.12 OIR56960.1 - 1.3e-31 110.1 0.0 1.7e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 PRA-PH PF01503.17 OIR56960.1 - 0.1 13.1 0.4 14 6.2 0.6 2.6 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase rve PF00665.26 OIR56961.1 - 2.1e-13 50.5 0.0 1.1e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR56961.1 - 7.7e-06 25.6 0.1 0.0004 20.1 0.1 2.7 1 1 1 2 2 2 2 Integrase core domain DNA_ligase_ZBD PF03119.16 OIR56962.1 - 0.082 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-RVT PF13966.6 OIR56962.1 - 0.091 13.5 0.3 0.25 12.1 0.1 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Nop PF01798.18 OIR56967.1 - 5.1e-76 255.2 0.0 7.4e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OIR56967.1 - 9.2e-14 51.6 0.6 2e-13 50.5 0.6 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF5028 PF16431.5 OIR56969.1 - 0.015 15.4 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5028) SAC3_GANP PF03399.16 OIR56970.1 - 3.5e-71 240.0 0.0 5.2e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family RT_RNaseH PF17917.1 OIR56975.1 - 5.4e-38 129.5 0.0 1.1e-37 128.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OIR56975.1 - 1.5e-35 121.2 0.0 3.1e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OIR56975.1 - 4.7e-34 117.8 0.0 9.3e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Poxvirus_B22R_C PF13168.6 OIR56977.1 - 0.034 13.6 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Pkinase PF00069.25 OIR56980.1 - 5.4e-31 107.9 0.4 3.4e-30 105.3 0.6 1.8 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR56980.1 - 9.9e-19 67.6 0.0 1.4e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR56980.1 - 7.4e-05 22.2 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OIR56980.1 - 0.018 14.1 0.1 0.027 13.5 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.29 OIR56989.1 - 1.5e-36 125.7 0.1 4.9e-36 124.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR56989.1 - 1.3e-08 34.5 0.0 5.1e-08 32.6 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 OIR56989.1 - 1.5e-06 28.1 0.1 1.4e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 OIR56989.1 - 2e-06 27.6 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OIR56989.1 - 2.9e-06 27.6 1.1 0.0015 18.8 0.3 3.6 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OIR56989.1 - 0.00013 22.0 0.1 0.0005 20.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OIR56989.1 - 0.0024 18.3 0.1 0.0024 18.3 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 OIR56989.1 - 0.0029 16.9 0.0 0.0062 15.8 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 OIR56989.1 - 0.0048 17.0 1.3 0.024 14.8 0.0 2.6 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 OIR56989.1 - 0.011 15.1 0.3 0.035 13.5 0.2 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OIR56989.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RED_N PF07808.13 OIR56989.1 - 0.019 14.6 3.1 0.034 13.7 3.1 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region AAA_11 PF13086.6 OIR56989.1 - 0.02 14.7 1.3 0.93 9.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OIR56989.1 - 0.074 13.2 0.5 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OIR56989.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OIR56989.1 - 0.13 12.7 0.0 0.72 10.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 OIR56989.1 - 0.14 11.7 0.3 1.1 8.9 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OIR56989.1 - 0.18 12.1 0.1 0.56 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Kri1 PF05178.12 OIR56989.1 - 0.22 12.1 9.1 0.56 10.8 9.1 1.7 1 0 0 1 1 1 0 KRI1-like family AAA_18 PF13238.6 OIR56989.1 - 0.25 11.9 0.0 0.25 11.9 0.0 2.5 2 1 0 2 2 1 0 AAA domain Borrelia_P83 PF05262.11 OIR56989.1 - 3.7 5.9 8.1 6.8 5.1 8.1 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Sin3_corepress PF08295.12 OIR56990.1 - 2.5e-23 82.0 0.4 5.4e-23 80.9 0.4 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 OIR56990.1 - 0.0026 17.9 0.0 19 5.5 0.0 3.8 3 0 0 3 3 3 2 Paired amphipathic helix repeat UDPGP PF01704.18 OIR56991.1 - 1.2e-28 99.9 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sec62 PF03839.16 OIR56992.1 - 1.2e-40 139.3 0.9 1.5e-40 139.0 0.9 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 HTH_22 PF13309.6 OIR56992.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 HTH domain 2TM PF13239.6 OIR56992.1 - 0.13 12.6 9.6 0.29 11.4 9.6 1.7 1 1 0 1 1 1 0 2TM domain Ribosomal_S19e PF01090.19 OIR56992.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e DUF2207 PF09972.9 OIR56992.1 - 0.17 10.6 0.6 0.2 10.4 0.6 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) GPI2 PF06432.11 OIR56992.1 - 1 8.7 4.6 1.4 8.3 4.6 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase zf-UBP PF02148.19 OIR56993.1 - 3.7e-18 65.6 6.0 3.7e-18 65.6 6.0 2.7 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 OIR56993.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 OIR56993.1 - 1.9e-06 27.5 14.6 0.005 16.6 6.9 3.1 2 0 0 2 2 2 2 Variant UBP zinc finger zinc_ribbon_9 PF14369.6 OIR56993.1 - 0.063 13.5 0.1 0.063 13.5 0.1 4.1 3 2 1 4 4 4 0 zinc-ribbon FbpA PF05833.11 OIR56995.1 - 0.039 12.7 4.2 0.05 12.4 4.2 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HSP70 PF00012.20 OIR56995.1 - 0.094 10.9 1.0 0.099 10.8 1.0 1.0 1 0 0 1 1 1 0 Hsp70 protein Chs7 PF12271.8 OIR56996.1 - 6.8e-06 25.7 0.1 8.7e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone dCache_2 PF08269.11 OIR56997.1 - 0.81 8.8 10.3 0.042 13.0 3.6 2.1 2 1 1 3 3 3 0 Cache domain DASH_Dad4 PF08650.10 OIR56997.1 - 2.6 8.1 5.6 3.4 7.7 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF724 PF05266.14 OIR56998.1 - 0.35 10.7 4.4 0.17 11.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Actin PF00022.19 OIR56999.1 - 1.7e-46 158.7 0.1 2.6e-41 141.6 0.0 2.9 1 1 1 2 2 2 2 Actin TetR_C_13 PF16925.5 OIR57000.1 - 0.037 13.9 4.7 0.54 10.2 1.2 2.6 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 OIR57001.1 - 3.4e-46 157.8 0.0 5.2e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57001.1 - 5.7e-25 88.1 0.0 7.7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR57001.1 - 2.4e-06 27.1 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OIR57001.1 - 7.2e-06 25.0 0.0 1.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OIR57001.1 - 0.00033 20.1 0.0 0.00092 18.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR57001.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.20 OIR57002.1 - 8.7e-63 212.8 0.0 1.4e-62 212.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FixQ PF05545.11 OIR57002.1 - 0.17 11.8 0.2 0.52 10.3 0.2 1.8 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RNase_PH PF01138.21 OIR57003.1 - 5.4e-10 39.9 0.0 1.4e-09 38.6 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OIR57003.1 - 0.047 13.7 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Glyco_transf_90 PF05686.12 OIR57004.1 - 1.8e-08 33.8 0.9 4e-07 29.3 0.2 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 SecA_DEAD PF07517.14 OIR57006.1 - 2.2e-28 99.4 0.1 2.2e-28 99.4 0.1 2.6 2 0 0 2 2 2 1 SecA DEAD-like domain DEAD PF00270.29 OIR57006.1 - 1.2e-09 38.1 3.9 4.9e-09 36.2 0.1 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase SecA_PP_bind PF01043.20 OIR57006.1 - 6.3e-06 26.8 0.0 4.2e-05 24.2 0.0 2.6 1 0 0 1 1 1 1 SecA preprotein cross-linking domain Helicase_C PF00271.31 OIR57006.1 - 0.017 15.4 3.6 0.02 15.2 0.5 2.9 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DUF5099 PF17025.5 OIR57006.1 - 0.57 10.6 3.5 1.7 9.1 2.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) MitMem_reg PF13012.6 OIR57007.1 - 0.081 13.4 0.4 0.081 13.4 0.4 3.4 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function Snapin_Pallidin PF14712.6 OIR57007.1 - 0.11 12.9 0.3 0.11 12.9 0.3 5.0 3 2 1 4 4 4 0 Snapin/Pallidin M_domain PF12938.7 OIR57007.1 - 0.35 10.6 3.0 0.13 12.0 0.2 1.6 2 0 0 2 2 2 0 M domain of GW182 DUF3138 PF11336.8 OIR57007.1 - 0.76 8.3 1.8 1.5 7.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_S28 PF05577.12 OIR57007.1 - 1.1 7.9 2.6 0.67 8.7 0.4 1.6 2 0 0 2 2 2 0 Serine carboxypeptidase S28 ATG16 PF08614.11 OIR57007.1 - 3.1 8.0 52.0 0.042 14.1 11.7 4.8 3 2 1 4 4 4 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 OIR57007.1 - 3.8 7.8 21.1 0.31 11.3 3.1 5.3 4 3 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OIR57007.1 - 4.7 7.2 7.0 21 5.2 0.4 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 OIR57008.1 - 8.8e-62 208.8 0.0 1.1e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57008.1 - 2.6e-31 108.8 0.0 3.9e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR57008.1 - 1.4e-09 37.7 0.0 2.4e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OIR57008.1 - 0.003 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR57008.1 - 0.0035 17.3 0.1 0.078 12.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OIR57008.1 - 0.0047 16.5 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OIR57008.1 - 0.0089 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain KA1 PF02149.19 OIR57008.1 - 0.029 14.2 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Kinase associated domain 1 STAC2_u1 PF16664.5 OIR57008.1 - 0.1 13.0 0.5 0.19 12.2 0.5 1.4 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Seadorna_VP7 PF07387.11 OIR57008.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DKCLD PF08068.12 OIR57009.1 - 1.5e-25 89.0 0.1 2.8e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.18 OIR57009.1 - 2e-23 83.4 0.1 4.6e-20 72.5 0.1 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OIR57009.1 - 1.3e-19 70.1 0.9 2.7e-19 69.1 0.9 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain P21-Arc PF04062.14 OIR57010.1 - 6.2e-24 85.0 0.0 1.2e-23 84.1 0.0 1.5 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit WD40 PF00400.32 OIR57011.1 - 7.3e-06 26.6 7.0 0.36 11.8 0.0 6.4 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57011.1 - 0.037 14.3 0.1 0.74 10.2 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_B PF00136.21 OIR57012.1 - 1.7e-101 340.2 0.0 6e-101 338.4 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OIR57012.1 - 7.7e-21 74.6 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 OIR57012.1 - 5.5e-07 28.5 0.0 8.6e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_2 PF03175.13 OIR57012.1 - 0.0001 21.3 0.0 0.00028 19.9 0.0 1.5 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral zf-DNA_Pol PF08996.10 OIR57012.1 - 0.014 15.1 1.2 0.13 12.0 1.5 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-trcl PF13451.6 OIR57012.1 - 0.49 10.3 13.1 7.1 6.6 0.6 3.7 3 0 0 3 3 3 0 Probable zinc-ribbon domain XPA_N PF01286.18 OIR57012.1 - 0.93 9.6 5.0 1.6 8.8 0.4 2.9 2 0 0 2 2 2 0 XPA protein N-terminal BAF250_C PF12031.8 OIR57013.1 - 3.4e-07 29.8 11.4 0.076 12.3 0.1 7.4 5 2 3 8 8 8 3 SWI/SNF-like complex subunit BAF250/Osa zf-C3HC4_3 PF13920.6 OIR57013.1 - 0.00021 21.1 4.8 0.00039 20.2 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3860 PF12976.7 OIR57013.1 - 0.014 15.4 1.5 23 5.1 0.0 6.2 9 0 0 9 9 9 0 Domain of Unknown Function with PDB structure (DUF3860) Reg_prop PF07494.11 OIR57013.1 - 0.025 14.8 4.5 1.2e+02 3.5 0.0 6.5 9 0 0 9 9 9 0 Two component regulator propeller DUF2507 PF10702.9 OIR57013.1 - 0.025 14.5 0.8 12 5.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2507) zf-UDP PF14569.6 OIR57013.1 - 0.11 12.6 3.3 0.21 11.7 3.3 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger SPATA6 PF14909.6 OIR57013.1 - 0.42 10.7 1.4 40 4.3 0.0 3.7 3 1 1 4 4 4 0 Spermatogenesis-assoc protein 6 FYVE_2 PF02318.16 OIR57013.1 - 0.88 9.8 13.1 0.048 13.9 4.7 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger DZR PF12773.7 OIR57013.1 - 1.6 8.8 3.2 5.4 7.1 3.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 OIR57014.1 - 0.0022 17.8 4.8 0.004 17.0 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2197 PF09963.9 OIR57014.1 - 0.037 14.3 0.8 0.037 14.3 0.8 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C4_Topoisom PF01396.19 OIR57014.1 - 0.054 13.3 0.5 0.15 11.9 0.5 1.8 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Peptidase_C37 PF05416.12 OIR57014.1 - 0.076 11.5 0.0 0.076 11.5 0.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf-C4_ClpX PF06689.13 OIR57014.1 - 3.1 7.7 8.2 5.6 6.9 5.7 2.4 2 1 1 3 3 3 0 ClpX C4-type zinc finger zf-C3HC4_3 PF13920.6 OIR57016.1 - 2.8e-05 23.9 7.1 5.1e-05 23.0 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OIR57016.1 - 8.1e-05 22.4 1.5 93 3.8 0.0 7.6 9 0 0 9 9 9 0 Two component regulator propeller zf-UDP PF14569.6 OIR57016.1 - 0.0011 19.1 4.1 0.0021 18.1 4.1 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger BAF250_C PF12031.8 OIR57016.1 - 0.0016 17.8 2.3 17 4.6 0.0 5.4 6 1 1 7 7 7 0 SWI/SNF-like complex subunit BAF250/Osa DUF3719 PF12516.8 OIR57016.1 - 0.0084 15.8 0.0 1.1 9.0 0.0 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF3719) FYVE_2 PF02318.16 OIR57016.1 - 0.049 13.8 6.2 0.21 11.8 6.2 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_2 PF13639.6 OIR57016.1 - 0.072 13.4 7.9 0.15 12.5 7.9 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OIR57016.1 - 0.34 10.8 5.1 4.7 7.1 5.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR57016.1 - 0.71 9.7 8.7 18 5.2 8.8 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OIR57016.1 - 1.2 9.5 4.5 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 OIR57016.1 - 1.3 9.1 4.4 3.2 7.8 4.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OIR57016.1 - 1.5 8.9 7.9 2.9 7.9 7.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 OIR57016.1 - 2.4 8.3 6.1 16 5.6 6.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OIR57016.1 - 4.4 6.9 5.4 7.5 6.2 0.2 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4 PF00097.25 OIR57016.1 - 5.6 6.9 7.7 16 5.5 7.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_pol_Rpb6 PF01192.22 OIR57017.1 - 0.16 11.9 0.6 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb6 zf-C2H2_11 PF16622.5 OIR57018.1 - 0.053 13.3 6.2 0.24 11.2 0.8 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type MCM PF00493.23 OIR57021.1 - 1.3e-96 322.0 0.0 2.1e-96 321.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OIR57021.1 - 7.2e-38 129.3 0.4 1.3e-37 128.5 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OIR57021.1 - 8.5e-26 90.2 1.3 2e-25 89.0 1.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OIR57021.1 - 1.3e-12 48.2 0.2 3.6e-12 46.8 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OIR57021.1 - 6e-07 29.6 0.0 2.2e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OIR57021.1 - 1.7e-06 27.6 0.1 2.8e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OIR57021.1 - 0.0017 18.2 0.1 0.0093 15.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OIR57021.1 - 0.026 14.2 0.2 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain MCM_bind PF09739.9 OIR57021.1 - 0.026 13.0 2.0 0.028 12.9 0.1 1.9 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor E1_4HB PF16191.5 OIR57021.1 - 0.17 12.1 0.1 0.88 9.8 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle MCPsignal PF00015.21 OIR57022.1 - 0.00094 19.0 0.4 0.00094 19.0 0.4 1.8 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 OIR57022.1 - 0.0029 18.0 4.4 0.49 10.8 0.2 2.7 2 1 1 3 3 3 2 Syntaxin-like protein UPF0242 PF06785.11 OIR57022.1 - 0.0055 16.8 1.4 0.0055 16.8 1.4 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Exo84_C PF16528.5 OIR57022.1 - 0.0079 16.0 1.7 0.011 15.5 1.7 1.3 1 0 0 1 1 1 1 Exocyst component 84 C-terminal NPV_P10 PF05531.12 OIR57022.1 - 0.039 14.4 0.4 4.3 7.9 0.1 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 OIR57022.1 - 0.062 13.8 1.8 0.63 10.6 0.4 2.6 1 1 0 2 2 2 0 Protein of unknown function DUF16 COG2 PF06148.11 OIR57022.1 - 0.064 13.3 8.5 2.8 8.0 0.3 3.4 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 TRPM_tetra PF16519.5 OIR57022.1 - 0.072 13.2 0.4 0.38 10.9 0.1 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Cob_adeno_trans PF01923.18 OIR57022.1 - 0.11 12.6 2.1 2 8.5 0.1 2.4 2 1 0 2 2 2 0 Cobalamin adenosyltransferase SNARE PF05739.19 OIR57022.1 - 0.14 12.2 6.8 0.3 11.1 3.1 2.7 2 1 0 2 2 2 0 SNARE domain BLOC1_2 PF10046.9 OIR57022.1 - 0.32 11.3 3.8 2.1 8.7 0.5 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BAR_3 PF16746.5 OIR57022.1 - 0.36 10.5 5.9 0.15 11.7 0.4 2.3 2 1 1 3 3 3 0 BAR domain of APPL family Spc7 PF08317.11 OIR57022.1 - 0.58 9.0 9.0 0.35 9.7 5.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 OIR57022.1 - 0.64 10.1 4.5 3.6 7.6 2.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Sec20 PF03908.13 OIR57022.1 - 0.76 9.7 3.5 3.8 7.5 0.3 2.9 2 1 1 3 3 3 0 Sec20 Sec2p PF06428.11 OIR57022.1 - 0.85 9.6 9.0 5.3 7.1 0.5 3.2 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Syntaxin-6_N PF09177.11 OIR57022.1 - 0.95 10.1 5.5 1.8 9.1 1.8 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CC2-LZ PF16516.5 OIR57022.1 - 1 9.8 5.2 1.1 9.7 0.6 2.9 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ERM PF00769.19 OIR57022.1 - 1.9 8.2 8.9 0.86 9.4 3.6 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF745 PF05335.13 OIR57022.1 - 2.9 7.6 9.9 3.6 7.3 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) KxDL PF10241.9 OIR57022.1 - 3.7 7.9 8.2 3.1 8.1 0.4 3.2 2 2 2 4 4 4 0 Uncharacterized conserved protein EMP24_GP25L PF01105.24 OIR57022.1 - 6.3 6.7 6.5 1.3e+02 2.4 6.5 2.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ADIP PF11559.8 OIR57022.1 - 9.6 6.3 9.4 28 4.8 3.8 2.3 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding NTF2 PF02136.20 OIR57023.1 - 0.091 13.3 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain BUD22 PF09073.10 OIR57023.1 - 1 8.7 17.4 1.9 7.7 17.4 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 OIR57023.1 - 1.2 7.4 9.7 1.5 7.0 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 OIR57023.1 - 1.3 9.0 11.9 0.35 10.8 6.7 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1242 PF06842.12 OIR57024.1 - 3.8e-18 65.0 0.4 5.8e-18 64.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF4519 PF15012.6 OIR57025.1 - 5.8e-07 29.6 2.7 5.8e-07 29.6 2.7 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4519) DUF5305 PF17231.2 OIR57025.1 - 0.00025 20.5 0.8 0.00025 20.5 0.8 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5305) DUF979 PF06166.12 OIR57025.1 - 0.006 15.8 0.2 0.0073 15.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF979) SARAF PF06682.12 OIR57025.1 - 0.0098 15.6 0.8 0.011 15.4 0.8 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PAPA-1 PF04795.12 OIR57025.1 - 0.0099 16.7 8.0 0.0099 16.7 8.0 2.1 2 0 0 2 2 2 1 PAPA-1-like conserved region E1-E2_ATPase PF00122.20 OIR57025.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 E1-E2 ATPase NatB_MDM20 PF09797.9 OIR57025.1 - 0.026 13.5 0.3 0.028 13.4 0.3 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Bac_rhodopsin PF01036.18 OIR57025.1 - 0.077 12.6 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein DUF3552 PF12072.8 OIR57025.1 - 0.097 12.1 15.4 0.029 13.8 4.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF3671 PF12420.8 OIR57025.1 - 0.14 12.2 1.9 0.26 11.4 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF4834 PF16118.5 OIR57025.1 - 0.17 12.8 0.3 0.17 12.8 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) DUF2207 PF09972.9 OIR57025.1 - 1.7 7.3 5.4 0.22 10.2 1.0 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Vfa1 PF08432.10 OIR57025.1 - 1.8 8.9 12.0 1.5 9.1 6.2 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MAP17 PF15807.5 OIR57025.1 - 3.6 7.8 9.8 0.14 12.4 0.7 2.0 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Sec23_trunk PF04811.15 OIR57026.1 - 5.3e-22 78.6 0.0 7.3e-20 71.6 0.0 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OIR57026.1 - 8e-13 49.0 0.0 1.3e-11 45.1 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OIR57026.1 - 2.3e-11 43.5 3.8 4.4e-11 42.6 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 OIR57026.1 - 0.059 14.0 0.3 5.7 7.6 0.2 2.7 2 1 0 2 2 2 0 von Willebrand factor type A domain BNR_4 PF15892.5 OIR57027.1 - 2.1e-05 24.0 0.5 0.0041 16.5 0.1 2.3 2 0 0 2 2 2 2 BNR repeat-containing family member SBBP PF06739.11 OIR57027.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Beta-propeller repeat Sugar_tr PF00083.24 OIR57028.1 - 0.3 9.9 0.7 0.42 9.4 0.7 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter Pkinase PF00069.25 OIR57029.1 - 1.4e-69 234.5 0.0 1.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57029.1 - 7.8e-35 120.4 0.0 9.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR57029.1 - 5.7e-06 25.9 0.0 7.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OIR57029.1 - 0.00023 20.6 0.1 0.00036 19.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR57029.1 - 0.00037 20.5 0.6 0.022 14.7 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 OIR57029.1 - 0.00041 19.9 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 OIR57029.1 - 0.00043 20.0 0.2 0.038 13.6 0.0 2.2 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 OIR57029.1 - 0.0018 17.2 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 OIR57029.1 - 0.02 14.5 0.1 0.05 13.2 0.1 1.6 1 1 1 2 2 2 0 Choline/ethanolamine kinase MCM PF00493.23 OIR57030.1 - 4e-96 320.5 0.2 5.7e-96 319.9 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OIR57030.1 - 9.4e-30 103.0 0.0 2.1e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OIR57030.1 - 1.7e-22 79.6 0.6 4.8e-22 78.2 0.0 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OIR57030.1 - 1.3e-12 48.2 0.0 6.8e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 OIR57030.1 - 1e-07 31.6 0.1 7.9e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OIR57030.1 - 0.0011 18.9 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OIR57030.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OIR57030.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1_like PF12832.7 OIR57032.1 - 1.7e-25 89.7 18.3 2.6e-25 89.1 18.3 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OIR57032.1 - 5.3e-18 65.1 24.4 2.1e-09 36.8 6.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.9 OIR57032.1 - 0.81 8.4 2.8 1.4 7.6 1.7 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2157 PF09925.9 OIR57032.1 - 1.2 8.9 11.1 0.043 13.6 2.4 2.9 2 2 1 3 3 3 0 Predicted membrane protein (DUF2157) SH2_2 PF14633.6 OIR57033.1 - 3.2e-40 137.8 0.0 5.3e-39 133.9 0.0 2.3 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 OIR57033.1 - 2.7e-13 50.2 0.0 6.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 OIR57033.1 - 1.3e-09 38.5 0.1 3.7e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 OIR57033.1 - 3.1e-05 24.0 0.0 0.0055 16.8 0.0 2.6 2 0 0 2 2 2 1 SH2 domain Tex_N PF09371.10 OIR57033.1 - 0.00027 20.7 0.0 0.00027 20.7 0.0 2.2 2 0 0 2 2 2 1 Tex-like protein N-terminal domain HHH_9 PF17674.1 OIR57033.1 - 0.0041 18.0 0.0 0.0041 18.0 0.0 3.0 3 0 0 3 3 3 1 HHH domain DUF4107 PF13389.6 OIR57033.1 - 0.19 11.9 0.0 0.53 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DUF5548 PF17702.1 OIR57034.1 - 0.11 12.3 0.0 37 4.0 0.0 3.2 1 1 1 3 3 3 0 Family of unknown function (DUF5548) PyrI_C PF02748.15 OIR57034.1 - 0.13 12.2 1.3 0.33 10.9 1.3 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C3HC4_3 PF13920.6 OIR57034.1 - 0.25 11.2 3.0 0.48 10.3 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR57035.1 - 0.0045 16.8 6.7 0.0093 15.8 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 OIR57035.1 - 0.16 11.9 9.1 0.29 11.1 9.1 1.4 1 0 0 1 1 1 0 PHD-finger PolC_DP2 PF03833.13 OIR57035.1 - 0.18 9.6 4.7 0.27 9.1 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Prok-RING_4 PF14447.6 OIR57035.1 - 0.61 10.0 7.9 4.9 7.1 7.9 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR57035.1 - 0.92 9.4 9.6 0.17 11.7 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OIR57035.1 - 1.2 9.5 10.4 3.7 8.0 10.4 1.9 1 1 0 1 1 1 0 Ring finger domain zinc-ribbons_6 PF07191.12 OIR57035.1 - 1.6 8.8 6.5 7.2 6.7 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-C2HC5 PF06221.13 OIR57035.1 - 2 8.5 7.0 1.4 8.9 1.6 2.5 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type HypA PF01155.19 OIR57035.1 - 2.9 7.9 9.8 1.1 9.3 1.3 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ATP-grasp_4 PF13535.6 OIR57037.1 - 0.037 13.6 0.2 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain Metalloenzyme PF01676.18 OIR57041.1 - 3.3e-73 246.1 0.0 3.8e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 OIR57041.1 - 3.3e-69 232.6 0.0 4.6e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 OIR57041.1 - 2.3e-08 34.0 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 OIR57041.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Sulfatase efThoc1 PF11957.8 OIR57042.1 - 7.9e-13 47.9 0.0 7e-12 44.8 0.0 1.9 1 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Telomere_reg-2 PF10193.9 OIR57043.1 - 0.002 18.6 3.4 0.012 16.1 0.2 3.2 3 0 0 3 3 3 1 Telomere length regulation protein Myb_DNA-bind_7 PF15963.5 OIR57044.1 - 2e-24 85.3 2.7 3.9e-24 84.3 2.7 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OIR57044.1 - 3.3e-06 27.2 0.1 8.9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR57044.1 - 0.013 15.7 1.0 0.025 14.8 0.5 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain WD40 PF00400.32 OIR57045.1 - 4.8e-33 112.7 12.9 5.2e-06 27.1 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57045.1 - 1.6e-14 54.0 0.2 0.0091 16.3 0.0 5.0 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 OIR57045.1 - 5.5e-09 36.2 6.1 1.1e-08 35.3 6.1 1.4 1 0 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 OIR57045.1 - 0.0093 15.0 0.3 0.93 8.4 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 OIR57045.1 - 0.012 15.2 0.0 0.071 12.7 0.0 2.1 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Rsd_AlgQ PF04353.13 OIR57045.1 - 0.078 12.9 1.2 0.16 11.9 1.2 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Ribosomal_L18A PF01775.17 OIR57046.1 - 3.2e-23 82.1 3.3 3.5e-23 82.0 3.3 1.0 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_L19e PF01280.20 OIR57048.1 - 2.2e-18 66.7 7.4 2.7e-18 66.4 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e NCD2 PF04905.13 OIR57049.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 NAB conserved region 2 (NCD2) Abhydrolase_1 PF00561.20 OIR57050.1 - 1.1e-10 41.6 0.0 3.8e-10 39.9 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OIR57050.1 - 4.8e-10 39.1 0.0 2.2e-09 36.9 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OIR57050.1 - 0.0004 21.0 0.0 0.00059 20.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OIR57050.1 - 0.0015 18.1 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OIR57050.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OIR57050.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF818 PF05677.12 OIR57050.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Glu-tRNAGln PF02686.15 OIR57051.1 - 0.025 14.9 0.1 0.075 13.3 0.0 1.9 1 1 1 2 2 2 0 Glu-tRNAGln amidotransferase C subunit DUF2175 PF09943.9 OIR57051.1 - 0.037 14.3 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) MutS_V PF00488.21 OIR57052.1 - 1.2e-38 133.1 0.0 2e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OIR57052.1 - 9e-19 68.4 0.0 2.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain III AAA_16 PF13191.6 OIR57052.1 - 0.0005 20.5 0.1 0.022 15.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OIR57052.1 - 0.002 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OIR57052.1 - 0.0097 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 OIR57052.1 - 0.01 15.3 0.0 0.2 11.1 0.0 2.8 3 1 1 4 4 4 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 OIR57052.1 - 0.015 15.3 0.0 0.49 10.3 0.0 3.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 OIR57052.1 - 0.042 14.3 0.6 0.37 11.2 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 OIR57052.1 - 0.042 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 OIR57052.1 - 0.058 13.7 0.2 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OIR57052.1 - 0.074 13.6 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 OIR57052.1 - 0.077 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OIR57052.1 - 0.12 12.9 0.1 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ubiquitin PF00240.23 OIR57053.1 - 5e-14 51.8 0.9 8.3e-14 51.1 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OIR57053.1 - 2.8e-08 33.5 0.1 5.9e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 OIR57053.1 - 3.5e-06 26.7 1.3 7.7e-06 25.7 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TerB_N PF13208.6 OIR57053.1 - 0.13 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 TerB N-terminal domain rRNA_processing PF08524.11 OIR57054.1 - 7.3e-07 29.3 12.4 1e-06 28.9 12.4 1.2 1 0 0 1 1 1 1 rRNA processing Rad60-SLD PF11976.8 OIR57055.1 - 4.4e-08 32.8 0.2 4.1e-07 29.7 0.5 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OIR57055.1 - 4.5e-05 23.1 0.3 0.0021 17.8 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin family Rhodanese PF00581.20 OIR57056.1 - 3.5e-10 40.3 0.0 6.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain CorA PF01544.18 OIR57062.1 - 1.1e-41 143.0 0.0 1.5e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2694 PF10904.8 OIR57062.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) zf-C3HC4_3 PF13920.6 OIR57067.1 - 1.5e-05 24.8 6.5 3e-05 23.8 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.15 OIR57067.1 - 0.089 12.8 2.0 8.8 6.5 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger zf-RING_2 PF13639.6 OIR57067.1 - 0.11 12.8 8.2 0.3 11.5 8.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 OIR57067.1 - 0.31 11.2 4.5 0.77 9.9 4.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR57067.1 - 0.67 10.2 3.8 2.1 8.6 3.8 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 OIR57067.1 - 1.2 9.1 8.3 2.8 7.9 8.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR57067.1 - 1.5 8.8 7.2 3.3 7.7 7.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Rhodanese_C PF12368.8 OIR57067.1 - 2.4 8.6 5.0 5.3 7.5 4.9 1.6 1 1 0 1 1 1 0 Rhodanase C-terminal zf-Di19 PF05605.12 OIR57067.1 - 3.8 7.9 8.7 3.1 8.2 3.3 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 OIR57067.1 - 8.9 6.4 7.1 48 4.1 7.6 1.8 1 1 1 2 2 2 0 Double zinc ribbon TnpV PF14198.6 OIR57068.1 - 0.00037 20.4 3.8 7.9 6.5 0.0 4.7 4 1 2 6 6 6 2 Transposon-encoded protein TnpV DUF4380 PF14315.6 OIR57068.1 - 0.0044 16.0 0.5 0.57 9.1 0.0 2.9 4 0 0 4 4 4 2 Domain of unknown function (DUF4380) ECSIT PF06239.11 OIR57068.1 - 0.094 11.8 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF3860 PF12976.7 OIR57068.1 - 0.11 12.5 0.1 44 4.2 0.0 4.2 4 1 1 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3860) Nucleic_acid_bd PF13820.6 OIR57068.1 - 0.16 11.8 3.0 71 3.2 0.0 4.6 6 0 0 6 6 6 0 Putative nucleic acid-binding region ANAPC15 PF15243.6 OIR57068.1 - 0.19 12.1 8.5 38 4.8 0.0 5.6 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 15 Sep15_SelM PF08806.11 OIR57069.1 - 0.021 15.0 0.1 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Sep15/SelM redox domain Ribosomal_S17e PF00833.18 OIR57069.1 - 0.18 11.7 0.6 0.85 9.6 0.2 1.9 1 1 1 2 2 2 0 Ribosomal S17 Zn_clus PF00172.18 OIR57070.1 - 0.3 11.2 6.4 0.49 10.6 6.4 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tail_VII PF17091.5 OIR57070.1 - 4.4 7.2 7.0 0.51 10.3 1.0 2.2 2 0 0 2 2 2 0 Inovirus G7P protein WBP-1 PF11669.8 OIR57070.1 - 6.6 7.4 9.0 4.2 8.1 7.2 1.6 1 1 0 1 1 1 0 WW domain-binding protein 1 DNA_RNApol_7kD PF03604.13 OIR57071.1 - 0.022 14.4 1.0 0.074 12.8 1.0 2.0 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit CCP_MauG PF03150.14 OIR57071.1 - 0.09 13.4 0.0 0.89 10.2 0.0 2.2 2 0 0 2 2 2 0 Di-haem cytochrome c peroxidase TACC_C PF05010.14 OIR57072.1 - 1.6e-29 103.2 31.1 2.7e-29 102.4 31.1 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Orn_Arg_deC_N PF02784.16 OIR57072.1 - 0.027 13.9 1.3 0.048 13.0 1.3 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF3450 PF11932.8 OIR57072.1 - 1 8.6 24.6 1.7 7.9 3.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Lectin_N PF03954.14 OIR57072.1 - 4 7.2 10.4 1.2 8.9 3.9 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain S1FA PF04689.13 OIR57073.1 - 0.12 12.5 0.5 0.28 11.3 0.5 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA BNR_4 PF15892.5 OIR57075.1 - 1.2e-15 57.6 1.7 8.8e-13 48.2 1.7 3.0 1 1 0 1 1 1 1 BNR repeat-containing family member tRNA_edit PF04073.15 OIR57076.1 - 0.022 14.9 0.2 2.1 8.5 0.1 2.9 3 0 0 3 3 3 0 Aminoacyl-tRNA editing domain YebG PF07130.12 OIR57076.1 - 0.32 10.9 1.3 15 5.5 0.0 2.7 3 0 0 3 3 3 0 YebG protein HC2 PF07382.11 OIR57079.1 - 0.061 13.4 8.1 0.11 12.6 8.1 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 GvpL_GvpF PF06386.11 OIR57079.1 - 0.95 9.3 0.0 0.95 9.3 0.0 2.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF2677 PF10838.8 OIR57081.1 - 0.04 13.9 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) BUD22 PF09073.10 OIR57083.1 - 0.00013 21.4 15.1 0.0002 20.8 15.1 1.2 1 0 0 1 1 1 1 BUD22 DDHD PF02862.17 OIR57083.1 - 0.00041 20.6 7.7 0.00041 20.6 7.7 2.2 1 1 1 2 2 2 1 DDHD domain RIFIN PF02009.16 OIR57083.1 - 0.065 13.1 19.5 0.13 12.1 18.1 1.8 2 0 0 2 2 2 0 Rifin CCSAP PF15748.5 OIR57083.1 - 0.65 10.1 20.2 0.38 10.9 12.5 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 OIR57083.1 - 1.6 8.0 29.0 0.076 12.4 18.4 2.1 2 0 0 2 2 2 0 SDA1 DUF1636 PF07845.11 OIR57083.1 - 1.7 9.1 6.9 1.9 9.0 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) DUF4045 PF13254.6 OIR57083.1 - 2.5 7.7 27.0 0.27 10.8 17.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF966 PF06136.13 OIR57083.1 - 2.5 7.8 22.0 1.7 8.3 16.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) SAPS PF04499.15 OIR57083.1 - 2.5 6.8 21.7 0.27 10.0 13.3 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein MID_MedPIWI PF18296.1 OIR57083.1 - 6.8 6.4 15.0 13 5.5 9.2 2.3 2 0 0 2 2 2 0 MID domain of medPIWI zf-C3HC4_3 PF13920.6 OIR57084.1 - 0.0079 16.0 2.8 0.017 15.0 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_10 PF16588.5 OIR57084.1 - 0.032 14.0 1.6 0.067 12.9 1.6 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger zf-RING_5 PF14634.6 OIR57084.1 - 0.53 10.3 5.2 1.7 8.6 5.3 1.9 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 OIR57084.1 - 0.54 10.2 5.2 1.3 9.0 5.2 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 OIR57084.1 - 0.72 9.8 3.7 1.7 8.6 3.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3253 PF11625.8 OIR57085.1 - 0.058 13.6 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Histidinol_dh PF00815.20 OIR57087.1 - 0.018 14.1 2.8 0.032 13.2 2.8 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase HIM1 PF08732.10 OIR57087.1 - 0.035 13.6 0.3 0.06 12.9 0.3 1.3 1 0 0 1 1 1 0 HIM1 YtzH PF14165.6 OIR57087.1 - 0.1 13.0 0.7 1.1 9.7 0.2 2.7 2 1 0 2 2 2 0 YtzH-like protein Colicin PF01024.19 OIR57087.1 - 0.18 11.7 4.0 0.27 11.1 4.0 1.3 1 0 0 1 1 1 0 Colicin pore forming domain Apolipoprotein PF01442.18 OIR57087.1 - 0.52 10.2 13.8 0.9 9.4 13.8 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CorA PF01544.18 OIR57087.1 - 1.3 8.2 4.8 1.8 7.8 4.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Remorin_C PF03763.13 OIR57087.1 - 8.6 6.3 15.9 6.8 6.6 10.6 2.9 3 1 0 3 3 3 0 Remorin, C-terminal region zf-C3HC4_3 PF13920.6 OIR57088.1 - 7.6e-06 25.7 7.7 1.6e-05 24.7 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Reg_prop PF07494.11 OIR57088.1 - 1.8e-05 24.4 2.5 24 5.6 0.0 5.6 5 0 0 5 5 5 1 Two component regulator propeller Prok-RING_4 PF14447.6 OIR57088.1 - 0.0045 16.8 7.4 0.011 15.6 7.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OIR57088.1 - 0.01 16.1 8.4 0.01 16.1 8.4 1.8 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.16 OIR57088.1 - 0.036 14.3 3.3 0.2 11.9 3.3 2.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR57088.1 - 0.042 13.6 7.2 0.1 12.4 7.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GcrA PF07750.11 OIR57088.1 - 0.16 12.4 4.3 15 6.0 0.0 4.4 3 2 1 5 5 5 0 GcrA cell cycle regulator RVT_1 PF00078.27 OIR57089.1 - 1.6e-10 40.9 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Wyosine_form PF08608.12 OIR57089.1 - 0.021 15.2 0.2 0.089 13.2 0.0 2.0 3 0 0 3 3 3 0 Wyosine base formation Acyl_transf_3 PF01757.22 OIR57092.1 - 0.07 12.2 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase family ATP-synt_C PF00137.21 OIR57093.1 - 4.2e-10 39.8 29.8 2.3e-06 27.9 13.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Proteasome PF00227.26 OIR57094.1 - 1.9e-34 118.8 1.2 2.6e-34 118.4 1.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR57094.1 - 5e-13 48.4 0.0 9.2e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature S1 PF00575.23 OIR57096.1 - 1.7e-09 37.9 0.1 2.7e-08 34.0 0.0 2.4 2 1 1 3 3 3 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 OIR57096.1 - 2.2e-08 34.3 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 OIR57096.1 - 0.015 15.6 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Choline_kinase PF01633.20 OIR57097.1 - 5.4e-24 85.0 0.0 8.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 OIR57097.1 - 2.5e-05 24.3 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_1 PF00515.28 OIR57098.1 - 1.2e-14 53.4 13.3 0.0019 17.9 0.1 7.5 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OIR57098.1 - 1.8e-14 52.6 13.1 0.0047 16.9 0.0 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 OIR57098.1 - 1.4e-10 40.5 3.9 1.7 8.9 0.0 6.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OIR57098.1 - 5.5e-09 35.5 16.5 0.025 14.8 0.1 7.9 8 1 2 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 OIR57098.1 - 2.2e-07 31.1 2.5 0.48 11.4 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR57098.1 - 1.2e-05 25.9 0.9 0.62 10.8 0.0 4.5 2 2 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR57098.1 - 2.2e-05 24.6 7.9 0.0019 18.4 2.2 3.7 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OIR57098.1 - 2.4e-05 24.8 1.2 0.5 10.9 0.3 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OIR57098.1 - 3.9e-05 24.0 4.1 0.53 11.0 0.0 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR57098.1 - 0.0003 21.0 13.1 0.12 12.6 0.3 6.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 OIR57098.1 - 0.0046 17.2 1.6 54 4.5 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 OIR57098.1 - 0.019 15.0 0.5 3 8.0 0.1 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Clathrin PF00637.20 OIR57098.1 - 0.038 13.9 2.0 0.12 12.2 0.2 2.6 2 0 0 2 2 2 0 Region in Clathrin and VPS Antimicrobial_8 PF08103.11 OIR57098.1 - 0.06 13.5 0.6 14 6.1 0.1 2.6 2 0 0 2 2 2 0 Uperin family Peptidase_M48 PF01435.18 OIR57100.1 - 3e-39 134.8 0.0 3e-39 134.8 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 OIR57100.1 - 1.5e-37 129.2 6.5 1.5e-37 129.2 6.5 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 OIR57100.1 - 5.7e-06 25.7 2.1 1.2e-05 24.7 2.1 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.9 OIR57100.1 - 0.12 11.9 0.2 0.22 11.1 0.2 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Pkinase PF00069.25 OIR57101.1 - 1.1e-75 254.5 0.0 1.2e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57101.1 - 6.9e-32 110.7 0.0 8.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR57101.1 - 7.8e-05 22.1 0.0 0.011 15.1 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 OIR57101.1 - 0.00019 21.5 0.0 0.013 15.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OIR57101.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Hist_deacetyl PF00850.19 OIR57102.1 - 1.4e-78 264.4 0.1 2.1e-78 263.9 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpb5_N PF03871.14 OIR57103.1 - 2.4e-21 76.1 1.7 2.7e-21 75.9 0.7 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.19 OIR57103.1 - 0.00042 20.1 0.4 0.0012 18.6 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Mrr_cat PF04471.12 OIR57103.1 - 0.016 15.2 0.1 0.036 14.1 0.1 1.6 1 1 0 1 1 1 0 Restriction endonuclease Sec5 PF15469.6 OIR57104.1 - 3.3e-11 43.4 0.8 2.4e-10 40.5 0.0 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 TBCA PF02970.16 OIR57107.1 - 2.6e-12 46.9 1.9 2.9e-12 46.7 1.9 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Val_tRNA-synt_C PF10458.9 OIR57107.1 - 0.057 13.7 0.1 0.13 12.6 0.1 1.8 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Rad9 PF04139.13 OIR57108.1 - 9e-17 61.3 0.1 1e-16 61.2 0.1 1.0 1 0 0 1 1 1 1 Rad9 rve PF00665.26 OIR57113.1 - 1.4e-06 28.5 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain zf_Rg PF17915.1 OIR57113.1 - 0.063 12.7 1.3 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger FHA_2 PF17913.1 OIR57114.1 - 0.0011 19.2 0.0 9.8 6.5 0.0 4.0 4 0 0 4 4 4 1 FHA domain DUF3929 PF13066.6 OIR57114.1 - 0.14 12.2 0.2 0.33 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) zf-C3HC4_3 PF13920.6 OIR57114.1 - 0.15 11.9 4.6 0.44 10.5 4.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) V4R PF02830.18 OIR57114.1 - 0.58 10.2 3.6 50 4.0 0.0 4.2 5 0 0 5 5 5 0 V4R domain Reg_prop PF07494.11 OIR57115.1 - 0.00031 20.6 1.2 9.4 6.9 0.0 5.5 5 0 0 5 5 5 1 Two component regulator propeller DUF1561 PF07598.11 OIR57115.1 - 0.031 12.5 0.0 5.2 5.2 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1561) Med6 PF04934.14 OIR57115.1 - 0.1 12.4 1.2 15 5.4 0.0 3.0 3 0 0 3 3 3 0 MED6 mediator sub complex component zf-RVT PF13966.6 OIR57116.1 - 0.062 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Ribosomal_L11_N PF03946.14 OIR57117.1 - 4.9e-18 64.7 0.5 9.4e-18 63.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OIR57117.1 - 4.4e-16 59.2 0.1 1e-15 57.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain ANAPC10 PF03256.16 OIR57118.1 - 3.4e-27 95.3 0.0 5.6e-27 94.6 0.0 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 OIR57118.1 - 9.2e-05 22.6 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain CRM1_C PF08767.11 OIR57119.1 - 1.4e-97 326.8 0.4 1.4e-97 326.8 0.4 2.5 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OIR57119.1 - 2e-32 112.3 2.6 2e-32 112.3 2.6 3.0 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OIR57119.1 - 8.8e-31 105.4 2.2 2.1e-30 104.1 2.2 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OIR57119.1 - 3.3e-25 87.9 0.6 1.1e-24 86.3 0.2 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 OIR57119.1 - 6.1e-15 54.9 1.5 1.4e-14 53.8 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 OIR57119.1 - 4.6e-12 45.2 0.3 1e-11 44.1 0.3 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Peptidase_M9_N PF08453.10 OIR57119.1 - 0.094 12.4 0.1 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M9 N-terminal Nha1_C PF08619.10 OIR57119.1 - 1 8.5 3.4 0.74 8.9 0.1 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Not1 PF04054.15 OIR57120.1 - 1.3e-54 185.5 0.0 1.3e-27 96.7 0.4 2.5 2 1 1 3 3 3 2 CCR4-Not complex component, Not1 Fe_dep_repr_C PF02742.15 OIR57120.1 - 0.16 12.1 3.3 1.9 8.6 0.1 3.4 4 0 0 4 4 4 0 Iron dependent repressor, metal binding and dimerisation domain Herpes_UL31 PF02718.14 OIR57123.1 - 0.083 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL31-like protein DUF1796 PF08795.10 OIR57125.1 - 0.017 15.1 0.0 1.6 8.7 0.0 2.0 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) YqbF PF14553.6 OIR57131.1 - 0.067 13.1 0.2 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 YqbF, hypothetical protein domain Alanine_zipper PF11839.8 OIR57131.1 - 4 7.9 30.1 3.7 8.0 10.2 3.1 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein PUNUT PF16913.5 OIR57132.1 - 0.1 11.8 3.9 0.063 12.5 2.4 1.4 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Unpaired PF15972.5 OIR57135.1 - 0.0011 18.6 0.0 1.3 8.5 0.0 3.5 2 1 2 4 4 4 3 Unpaired protein zf-C3HC4_3 PF13920.6 OIR57136.1 - 0.0091 15.8 5.1 0.018 14.9 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sep15_SelM PF08806.11 OIR57137.1 - 0.0038 17.4 36.4 1.2 9.4 0.0 11.6 11 3 2 14 14 14 2 Sep15/SelM redox domain ATP-grasp PF02222.22 OIR57137.1 - 0.084 12.4 0.1 0.33 10.5 0.1 2.0 1 1 1 2 2 2 0 ATP-grasp domain DUF555 PF04475.12 OIR57137.1 - 0.21 11.9 2.7 48 4.3 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF555) zf-C3HC4_3 PF13920.6 OIR57137.1 - 0.58 10.1 5.9 1.1 9.2 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C21 PF05381.12 OIR57137.1 - 0.64 10.4 2.4 29 5.1 0.1 3.8 3 0 0 3 3 3 0 Tymovirus endopeptidase DUF3989 PF13150.6 OIR57137.1 - 0.89 9.3 5.9 12 5.7 0.1 5.7 8 0 0 8 8 8 0 Protein of unknown function (DUF3989) UQ_con PF00179.26 OIR57138.1 - 1.2e-41 141.7 0.0 2e-41 140.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57138.1 - 4.7e-05 23.1 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UQ_con PF00179.26 OIR57139.1 - 5.6e-46 155.7 0.0 7.9e-46 155.2 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57139.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 OIR57139.1 - 0.072 13.4 0.0 0.18 12.1 0.0 1.7 1 1 1 2 2 2 0 RWD domain UQ_con PF00179.26 OIR57140.1 - 1.5e-43 147.8 0.0 2.5e-43 147.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57140.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OIR57140.1 - 0.015 15.6 0.9 0.028 14.7 0.1 1.9 2 1 0 2 2 2 0 RWD domain UQ_con PF00179.26 OIR57141.1 - 4.4e-43 146.3 0.0 9e-43 145.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57141.1 - 0.0053 16.5 0.0 0.0081 15.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 OIR57141.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 OIR57141.1 - 0.03 14.6 0.1 0.055 13.7 0.1 1.6 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.26 OIR57142.1 - 3.3e-46 156.4 0.0 3.8e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57142.1 - 4.4e-05 23.2 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 OIR57142.1 - 0.00034 20.3 0.0 0.00055 19.6 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 OIR57142.1 - 0.12 12.7 0.1 0.26 11.6 0.1 1.6 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.26 OIR57143.1 - 7.9e-10 38.5 0.0 1.3e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Herpes_gE PF02480.16 OIR57143.1 - 0.12 11.1 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Polo_box_2 PF18531.1 OIR57143.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Polo box domain UQ_con PF00179.26 OIR57144.1 - 3e-38 130.6 0.0 4.5e-38 130.1 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.26 OIR57145.1 - 1.1e-44 151.4 0.0 1.3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57145.1 - 2.5e-05 24.0 0.0 3.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 OIR57145.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 OIR57145.1 - 0.07 13.0 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 UEV domain RINT1_TIP1 PF04437.13 OIR57146.1 - 1.7e-15 56.9 4.2 4.2e-15 55.6 4.2 1.5 1 1 0 1 1 1 1 RINT-1 / TIP-1 family FYRC PF05965.14 OIR57147.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Prominin PF05478.11 OIR57147.1 - 0.047 11.7 0.3 0.057 11.4 0.3 1.0 1 0 0 1 1 1 0 Prominin RasGAP_C PF03836.15 OIR57147.1 - 0.072 13.2 1.0 0.1 12.7 1.0 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Imm42 PF15593.6 OIR57147.1 - 0.089 13.3 1.4 6.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 42 PIN_2 PF10130.9 OIR57147.1 - 0.098 12.9 1.9 0.18 12.1 1.9 1.4 1 0 0 1 1 1 0 PIN domain CPSF_A PF03178.15 OIR57148.1 - 2.3e-48 165.2 0.0 7.5e-47 160.2 0.0 2.9 3 0 0 3 3 3 1 CPSF A subunit region FtsJ PF01728.19 OIR57149.1 - 1.1e-59 201.5 0.1 1.2e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OIR57149.1 - 0.0043 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 OIR57149.1 - 0.034 14.8 0.0 0.071 13.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OIR57149.1 - 0.17 11.7 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Sybindin PF04099.12 OIR57150.1 - 4.4e-09 36.4 0.0 5.5e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Dynactin PF12455.8 OIR57150.1 - 0.032 13.5 0.3 0.047 12.9 0.3 1.2 1 0 0 1 1 1 0 Dynein associated protein WH1 PF00568.23 OIR57151.1 - 3.1e-12 46.4 0.2 5.2e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 OIR57151.1 - 3.9e-10 39.9 0.2 1e-09 38.6 0.1 1.8 1 1 0 1 1 1 1 P21-Rho-binding domain DUF1176 PF06674.11 OIR57151.1 - 0.14 11.6 4.5 0.22 11.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) RICTOR_M PF14666.6 OIR57152.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain HU-CCDC81_bac_2 PF18175.1 OIR57152.1 - 0.023 14.5 0.2 0.036 13.9 0.2 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DUF573 PF04504.14 OIR57152.1 - 0.028 15.1 0.4 0.29 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF573 GTP-bdg_M PF16360.5 OIR57152.1 - 0.86 10.2 5.0 0.33 11.6 2.6 1.5 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Peptidase_S8 PF00082.22 OIR57153.1 - 1.1e-33 116.8 3.3 1.1e-33 116.8 3.3 2.0 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 OIR57153.1 - 0.0094 16.6 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosomal_L38e PF01781.18 OIR57154.1 - 1.5e-12 47.4 0.1 1.8e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family SMC_N PF02463.19 OIR57155.1 - 2.9e-68 229.6 1.6 4e-68 229.1 1.6 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OIR57155.1 - 6.2e-23 81.3 0.0 1.5e-22 80.1 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 OIR57155.1 - 9e-15 55.3 1.9 4.5e-11 43.1 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OIR57155.1 - 4.4e-12 46.4 6.8 1.8e-06 28.0 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OIR57155.1 - 5.8e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OIR57155.1 - 0.014 15.9 22.7 0.033 14.7 0.1 5.9 3 2 0 3 3 3 0 ABC transporter DUF1298 PF06974.13 OIR57156.1 - 0.041 13.8 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) tRNA_anti-codon PF01336.25 OIR57156.1 - 0.066 13.2 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Med10 PF09748.9 OIR57157.1 - 3.7e-14 52.7 0.0 4.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex CxC7 PF18866.1 OIR57157.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 OIR57158.1 - 8.4e-35 118.2 22.1 1e-06 29.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57158.1 - 1.7e-14 53.9 4.4 0.0015 18.8 0.1 5.6 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OIR57158.1 - 2.2e-13 50.5 0.1 2e-05 24.6 0.1 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OIR57158.1 - 0.00067 19.1 0.0 0.054 12.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 OIR57158.1 - 0.037 13.0 0.4 1.4 7.8 0.1 3.2 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein KIX_2 PF16987.5 OIR57159.1 - 6.1e-07 29.4 2.2 1.4e-06 28.2 2.2 1.6 1 0 0 1 1 1 1 KIX domain DDE_Tnp_ISL3 PF01610.17 OIR57159.1 - 0.016 14.9 0.9 0.044 13.5 0.4 1.8 1 1 0 1 1 1 0 Transposase EloA-BP1 PF15870.5 OIR57159.1 - 0.083 13.1 1.2 0.12 12.6 0.4 1.6 2 0 0 2 2 2 0 ElonginA binding-protein 1 DUF883 PF05957.13 OIR57159.1 - 3.9 8.2 5.5 1.7 9.3 0.5 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Med14 PF08638.11 OIR57161.1 - 2.9e-11 43.2 0.1 5e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkinase PF00069.25 OIR57162.1 - 4.2e-33 114.8 0.0 5.6e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57162.1 - 1.6e-12 47.3 0.0 4.4e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR57162.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OIR57162.1 - 0.019 14.9 0.0 0.07 13.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OIR57162.1 - 0.049 13.2 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 OIR57162.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Prefoldin_2 PF01920.20 OIR57163.1 - 0.0034 17.3 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit PQQ_2 PF13360.6 OIR57164.1 - 0.07 12.7 0.0 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain Cytochrom_B_C PF00032.17 OIR57164.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Gram_pos_anchor PF00746.21 OIR57164.1 - 0.19 11.7 1.3 0.65 10.0 1.3 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Arf PF00025.21 OIR57166.1 - 6.6e-65 217.8 0.0 7.5e-65 217.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OIR57166.1 - 6.4e-11 42.0 0.0 8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OIR57166.1 - 7.3e-11 41.8 0.2 9.9e-07 28.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OIR57166.1 - 2.1e-09 37.6 0.0 4.1e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OIR57166.1 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OIR57166.1 - 5.8e-08 32.4 0.0 7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OIR57166.1 - 6.2e-08 32.4 0.0 7.1e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Ras family cobW PF02492.19 OIR57166.1 - 0.04 13.5 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OIR57166.1 - 0.052 13.4 0.1 0.82 9.5 0.1 2.1 1 1 1 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 OIR57166.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OIR57166.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 OIR57166.1 - 0.15 11.6 0.1 0.32 10.5 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC2_membrane PF01061.24 OIR57167.1 - 6.4e-29 100.9 7.5 6.4e-29 100.9 7.5 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OIR57167.1 - 3.4e-26 92.4 0.2 1.2e-25 90.7 0.2 1.8 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 OIR57167.1 - 7.3e-06 26.0 0.7 1.4e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 OIR57167.1 - 0.00036 20.0 0.0 0.0035 16.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OIR57167.1 - 0.00064 19.6 1.3 0.32 10.8 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 OIR57167.1 - 0.00066 19.4 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.7 OIR57167.1 - 0.0036 16.5 13.2 0.0064 15.6 13.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Zeta_toxin PF06414.12 OIR57167.1 - 0.025 13.8 0.1 0.049 12.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 OIR57167.1 - 0.026 15.1 1.8 0.045 14.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OIR57167.1 - 0.03 14.1 0.4 0.068 12.9 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 OIR57167.1 - 0.04 13.5 0.4 0.075 12.6 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OIR57167.1 - 0.057 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 OIR57167.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OIR57167.1 - 0.16 11.5 0.1 0.36 10.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 OIR57168.1 - 1.6e-24 86.3 0.0 2.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 OIR57168.1 - 1.7e-08 34.7 0.0 7e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OIR57168.1 - 0.0065 16.2 0.3 0.066 12.9 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase FHA_2 PF17913.1 OIR57170.1 - 0.00079 19.6 0.0 0.75 10.1 0.0 2.2 2 0 0 2 2 2 2 FHA domain DUF2110 PF09883.9 OIR57171.1 - 0.024 14.2 0.1 0.062 12.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2110) KCT2 PF17818.1 OIR57172.1 - 0.036 14.2 0.5 0.067 13.3 0.5 1.4 1 0 0 1 1 1 0 Keratinocyte-associated gene product DUF4428 PF14471.6 OIR57173.1 - 0.0072 16.2 0.4 0.0072 16.2 0.4 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4428) CDH1_2_SANT_HL1 PF18375.1 OIR57173.1 - 3.5 8.4 5.6 0.69 10.6 0.5 2.4 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Glyco_hydro_19 PF00182.19 OIR57174.1 - 1.7e-11 44.5 0.0 3.9e-11 43.3 0.0 1.6 1 1 1 2 2 2 1 Chitinase class I Unpaired PF15972.5 OIR57174.1 - 0.049 13.2 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Unpaired protein UCH PF00443.29 OIR57175.1 - 4e-42 144.5 0.2 5.7e-42 144.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR57175.1 - 9.1e-21 74.8 0.1 9.6e-19 68.1 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PhoLip_ATPase_C PF16212.5 OIR57176.1 - 2.5e-34 119.1 19.7 2.5e-34 119.1 19.7 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OIR57176.1 - 1.9e-18 65.9 0.3 4.2e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 OIR57176.1 - 1.4e-14 54.1 0.2 1.4e-14 54.1 0.2 2.8 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OIR57176.1 - 1.5e-14 54.8 0.6 1.3e-11 45.2 0.6 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OIR57176.1 - 3.1e-09 36.8 0.0 4.1e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OIR57176.1 - 0.036 13.8 0.3 0.39 10.4 0.1 2.7 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4079 PF13301.6 OIR57176.1 - 0.11 12.6 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Cation_ATPase_C PF00689.21 OIR57177.1 - 0.001 18.8 11.4 0.0015 18.3 11.4 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus YdjM PF04307.14 OIR57177.1 - 0.047 13.0 5.1 0.1 11.9 5.1 1.7 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF1218 PF06749.12 OIR57177.1 - 4.8 7.8 13.7 18 5.9 4.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Sep15_SelM PF08806.11 OIR57179.1 - 2.8e-13 49.8 19.6 0.0019 18.3 0.1 8.2 6 2 1 8 8 8 4 Sep15/SelM redox domain EXOSC1 PF10447.9 OIR57179.1 - 1.8e-09 38.1 1.8 2.7 8.7 0.0 5.5 3 2 2 5 5 5 3 Exosome component EXOSC1/CSL4 TMEM191C PF15194.6 OIR57179.1 - 1.2e-05 25.5 0.1 39 4.4 0.0 5.9 5 1 1 6 6 6 0 TMEM191C family zf-C3HC4_3 PF13920.6 OIR57179.1 - 0.00018 21.3 4.0 0.00032 20.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC15 PF15243.6 OIR57179.1 - 0.00018 21.8 9.9 5.4 7.5 0.0 5.9 6 0 0 6 6 6 3 Anaphase-promoting complex subunit 15 BAF250_C PF12031.8 OIR57179.1 - 0.037 13.3 4.4 27 3.9 0.1 4.8 1 1 4 5 5 4 0 SWI/SNF-like complex subunit BAF250/Osa Tudor_2 PF18104.1 OIR57179.1 - 0.063 13.0 0.0 64 3.4 0.0 4.1 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain Antimicrobial_1 PF08018.11 OIR57179.1 - 0.091 12.9 2.4 76 3.6 0.1 4.4 3 0 0 3 3 3 0 Frog antimicrobial peptide BamHI PF02923.15 OIR57179.1 - 0.37 10.5 4.8 10 5.8 0.1 3.4 4 1 0 4 4 4 0 Restriction endonuclease BamHI zf-C3HC4_5 PF17121.5 OIR57179.1 - 2.6 8.0 4.8 4.5 7.3 4.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MCRA PF06100.11 OIR57179.1 - 3.7 6.2 8.1 1.5 7.5 0.1 3.3 3 1 1 5 5 5 0 MCRA family Pkinase PF00069.25 OIR57180.1 - 1.8e-30 106.2 0.1 4.9e-29 101.5 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57180.1 - 3.8e-17 62.4 0.1 5.7e-17 61.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR57180.1 - 0.00022 20.3 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OIR57180.1 - 0.0014 18.6 0.2 0.093 12.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OIR57180.1 - 0.0022 17.4 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OIR57181.1 - 4.4e-31 108.2 0.9 6.5e-31 107.7 0.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57181.1 - 1.6e-18 66.9 0.1 2.4e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57181.1 - 0.00011 21.7 0.1 0.00018 20.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OIR57181.1 - 0.003 17.2 0.6 0.042 13.4 0.4 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 OIR57181.1 - 0.011 15.4 1.2 0.027 14.1 1.2 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OIR57181.1 - 0.024 13.6 0.2 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OIR57182.1 - 5.8e-33 114.4 0.9 2.2e-32 112.5 1.8 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57182.1 - 1.4e-22 80.2 0.3 2.2e-22 79.6 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57182.1 - 7e-06 25.5 0.4 1.1e-05 24.9 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR57182.1 - 6.3e-05 22.1 0.4 9.8e-05 21.5 0.4 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OIR57182.1 - 0.023 14.0 0.1 0.62 9.3 0.0 2.1 1 1 1 2 2 2 0 Kinase-like APH PF01636.23 OIR57182.1 - 0.039 13.9 0.0 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Phage_int_SAM_1 PF02899.17 OIR57182.1 - 0.17 12.2 0.4 0.48 10.7 0.1 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.25 OIR57184.1 - 9e-35 120.3 0.7 6e-34 117.6 1.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57184.1 - 9.8e-19 67.6 0.1 1.6e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57184.1 - 4.8e-05 22.8 0.1 8.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR57184.1 - 0.00028 20.9 0.0 0.19 11.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR57184.1 - 0.005 16.2 0.0 0.036 13.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 OIR57184.1 - 0.021 14.5 0.3 1.9 8.1 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 OIR57184.1 - 0.032 13.2 0.3 0.07 12.1 0.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 OIR57185.1 - 3.5e-32 111.8 0.9 1.2e-31 110.1 0.8 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57185.1 - 6e-20 71.6 0.1 1e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57185.1 - 5.4e-06 25.9 0.1 1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR57185.1 - 0.00085 19.0 1.1 0.0023 17.5 0.9 1.7 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OIR57185.1 - 0.0013 17.8 0.1 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OIR57185.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.5 1 1 1 2 2 2 0 Kinase-like Choline_kinase PF01633.20 OIR57185.1 - 0.069 12.7 0.2 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 OIR57186.1 - 1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57186.1 - 0.00021 20.7 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PRKCSH-like PF12999.7 OIR57187.1 - 0.1 12.4 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like POT1 PF02765.17 OIR57188.1 - 1.7e-06 27.9 0.0 4.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Tubulin_3 PF14881.6 OIR57190.1 - 0.00024 20.9 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 OIR57190.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain RTC_insert PF05189.13 OIR57191.1 - 5.2e-26 91.2 0.0 1.2e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 OIR57191.1 - 1.7e-25 89.6 0.0 5.7e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase SNARE PF05739.19 OIR57192.1 - 2.9e-07 30.4 0.0 9e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OIR57192.1 - 0.00014 21.6 5.7 0.0025 17.5 5.7 2.1 1 1 0 1 1 1 1 Syntaxin BLOC1_2 PF10046.9 OIR57192.1 - 0.0045 17.2 0.0 3.3 8.1 0.0 2.8 3 0 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 OIR57192.1 - 0.015 15.8 2.7 0.019 15.4 0.3 2.3 2 2 1 3 3 3 0 Protein of unknown function DUF16 DUF1664 PF07889.12 OIR57192.1 - 0.049 13.7 1.8 1.3 9.1 0.3 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_S6 PF01250.17 OIR57192.1 - 0.087 13.1 0.1 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S6 MCPsignal PF00015.21 OIR57192.1 - 0.11 12.4 1.2 1.1 9.0 0.7 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.21 OIR57192.1 - 0.15 11.8 4.8 0.44 10.4 0.9 3.0 3 1 0 3 3 3 0 Synaptobrevin Use1 PF09753.9 OIR57192.1 - 0.19 11.4 2.7 0.75 9.5 2.0 2.3 1 1 1 2 2 2 0 Membrane fusion protein Use1 UPF0242 PF06785.11 OIR57192.1 - 0.94 9.6 4.3 0.49 10.5 1.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 OIR57192.1 - 1.7 8.6 9.0 0.65 10.0 5.0 2.0 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Rib_5-P_isom_A PF06026.14 OIR57193.1 - 4.9e-30 104.4 0.0 8.6e-30 103.6 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) TFIIS_C PF01096.18 OIR57194.1 - 2.1e-15 56.3 2.9 2.1e-15 56.3 2.9 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zinc_ribbon_9 PF14369.6 OIR57194.1 - 0.0001 22.5 5.1 3.2 8.1 0.0 4.1 4 0 0 4 4 4 2 zinc-ribbon DZR PF12773.7 OIR57194.1 - 0.00052 20.0 8.2 0.12 12.4 1.4 2.5 2 1 0 2 2 2 2 Double zinc ribbon Auto_anti-p27 PF06677.12 OIR57194.1 - 0.0014 18.7 12.0 0.17 12.1 4.6 2.9 2 1 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc-ribbons_6 PF07191.12 OIR57194.1 - 0.0025 17.8 8.3 0.18 11.8 0.5 2.6 2 1 1 3 3 3 2 zinc-ribbons Zn_ribbon_recom PF13408.6 OIR57194.1 - 0.0033 17.9 1.4 2.7 8.6 0.1 2.3 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain IBR PF01485.21 OIR57194.1 - 0.004 17.4 5.3 0.24 11.6 0.5 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 OIR57194.1 - 0.0066 15.8 10.1 0.79 9.2 0.3 4.0 4 0 0 4 4 4 2 zinc-ribbon domain DUF3268 PF11672.8 OIR57194.1 - 0.026 14.8 0.2 0.026 14.8 0.2 1.9 2 0 0 2 2 2 0 zinc-finger-containing domain zf-RING_7 PF02591.15 OIR57194.1 - 0.034 14.3 2.0 14 6.0 0.1 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain CpXC PF14353.6 OIR57194.1 - 0.039 14.0 8.7 0.4 10.7 0.1 3.1 1 1 2 3 3 3 0 CpXC protein HypA PF01155.19 OIR57194.1 - 0.054 13.5 8.6 2.6 8.1 0.7 2.9 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_ligase_ZBD PF03119.16 OIR57194.1 - 0.079 13.0 1.7 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-H2C2_2 PF13465.6 OIR57194.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.6 4 1 0 4 4 3 0 Zinc-finger double domain Terminase_GpA PF05876.12 OIR57194.1 - 0.21 10.1 2.4 0.12 10.9 0.7 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) NOB1_Zn_bind PF08772.11 OIR57194.1 - 0.32 11.2 12.7 1.4 9.1 2.9 3.0 2 2 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like eIF-5_eIF-2B PF01873.17 OIR57194.1 - 0.43 10.5 7.4 0.12 12.2 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OIR57194.1 - 0.58 9.7 11.8 0.43 10.1 5.1 3.5 3 1 0 3 3 3 0 TFIIB zinc-binding zf_UBZ PF18439.1 OIR57194.1 - 0.61 9.7 0.1 0.61 9.7 0.1 4.0 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3 PF13878.6 OIR57194.1 - 0.79 9.6 7.8 16 5.4 0.1 3.4 3 1 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO DUF1610 PF07754.11 OIR57194.1 - 0.93 9.5 7.4 8.9 6.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zinc_ribbon_4 PF13717.6 OIR57194.1 - 1.1 9.2 9.8 1.1 9.3 0.1 3.3 3 1 0 3 3 3 0 zinc-ribbon domain PADR1 PF08063.12 OIR57194.1 - 1.4 8.7 8.0 2.7 7.8 0.1 3.1 3 0 0 3 3 3 0 PADR1 (NUC008) domain zf-TFIIB PF13453.6 OIR57194.1 - 1.5 8.3 8.8 0.081 12.3 3.1 2.0 2 1 0 2 2 1 0 Transcription factor zinc-finger DNA_RNApol_7kD PF03604.13 OIR57194.1 - 1.6 8.4 7.6 31 4.4 0.1 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-IS66 PF13005.7 OIR57194.1 - 2.1 8.8 8.0 2.4 8.6 0.1 3.2 3 1 0 3 3 3 0 zinc-finger binding domain of transposase IS66 UPF0547 PF10571.9 OIR57194.1 - 3.1 8.0 11.5 6.8 6.9 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.10 OIR57194.1 - 4.2 7.2 11.3 9.3 6.1 0.4 3.7 4 0 0 4 4 4 0 A2L zinc ribbon domain RNA_POL_M_15KD PF02150.16 OIR57194.1 - 5.1 7.1 14.6 9.1 6.3 2.7 3.4 2 2 0 2 2 2 0 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 OIR57194.1 - 7.6 6.7 17.0 1.7 8.8 1.6 3.8 2 2 1 4 4 4 0 Zinc ribbon domain zf-ISL3 PF14690.6 OIR57194.1 - 8.5 7.1 11.2 8.7 7.1 0.1 3.4 3 1 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HTH_17 PF12728.7 OIR57195.1 - 0.042 14.0 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RNA_pol_Rpb2_6 PF00562.28 OIR57198.1 - 8.3e-124 413.6 0.0 1.2e-123 413.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OIR57198.1 - 1.4e-56 191.3 0.0 2e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OIR57198.1 - 7.3e-31 106.4 0.2 1.9e-30 105.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OIR57198.1 - 3.3e-30 105.1 0.0 6e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 OIR57198.1 - 2.5e-26 91.6 0.0 6e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OIR57198.1 - 1.1e-19 70.4 0.0 2.9e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OIR57198.1 - 1.7e-17 63.7 0.2 4.7e-17 62.3 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE_2 PF02318.16 OIR57198.1 - 0.33 11.2 2.4 0.8 9.9 2.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4253 PF14062.6 OIR57199.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Zip PF02535.22 OIR57200.1 - 4.5e-31 108.3 29.2 7e-29 101.1 29.2 2.6 1 1 0 1 1 1 1 ZIP Zinc transporter ABC2_membrane PF01061.24 OIR57200.1 - 3.8 6.9 9.3 0.37 10.2 4.1 2.0 2 0 0 2 2 2 0 ABC-2 type transporter TPT PF03151.16 OIR57202.1 - 5e-19 68.7 14.0 5.9e-19 68.5 14.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OIR57202.1 - 3.9e-08 33.5 25.1 2.4e-05 24.5 8.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family CS PF04969.16 OIR57203.1 - 0.22 12.6 1.2 33 5.6 0.0 2.7 2 0 0 2 2 2 0 CS domain TPT PF03151.16 OIR57204.1 - 1.3e-19 70.7 20.4 1.5e-19 70.5 20.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OIR57204.1 - 4.7e-09 36.5 25.9 2.1e-07 31.2 7.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OIR57204.1 - 0.0053 16.0 24.1 0.0073 15.5 24.1 1.1 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 OIR57204.1 - 7.5 6.6 12.4 0.24 11.4 1.7 3.3 3 1 1 4 4 4 0 Putative transmembrane family 234 Homeobox_KN PF05920.11 OIR57205.1 - 1.1e-14 54.1 1.1 1.9e-14 53.3 1.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OIR57205.1 - 3.8e-08 33.0 1.2 6.2e-08 32.4 0.2 1.9 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 OIR57205.1 - 0.001 18.5 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Vta1 PF04652.16 OIR57206.1 - 4.9e-11 42.8 0.8 4.9e-11 42.8 0.8 2.4 2 1 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OIR57206.1 - 0.0012 18.5 0.0 0.0044 16.7 0.0 2.1 2 0 0 2 2 2 1 Vta1 C-terminal domain TetR_C_15 PF17918.1 OIR57206.1 - 0.021 15.6 1.3 0.047 14.4 0.6 1.9 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain RMI1_N PF08585.12 OIR57206.1 - 0.046 13.5 0.4 0.059 13.1 0.4 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Homeodomain PF00046.29 OIR57208.1 - 8.7e-14 51.1 4.5 8.7e-14 51.1 4.5 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OIR57208.1 - 1.2e-05 25.1 0.5 3.1e-05 23.8 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OIR57208.1 - 0.00092 18.6 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Polysacc_deac_1 PF01522.21 OIR57209.1 - 7.2e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase PepSY_2 PF13670.6 OIR57209.1 - 0.023 14.7 3.0 0.29 11.2 0.0 3.0 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain RE_HaeIII PF09556.10 OIR57209.1 - 0.12 11.5 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease RhoGEF PF00621.20 OIR57210.1 - 5.5e-25 88.6 1.2 1.1e-24 87.7 1.2 1.5 1 0 0 1 1 1 1 RhoGEF domain Fanconi_A PF03511.14 OIR57210.1 - 0.13 12.2 0.0 0.53 10.2 0.0 2.1 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF1217 PF06748.12 OIR57211.1 - 0.12 12.4 0.0 0.83 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1217) zf-RING_14 PF17978.1 OIR57213.1 - 0.059 13.8 1.0 0.1 13.0 1.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OIR57214.1 - 0.0017 18.2 7.4 0.0026 17.6 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR57214.1 - 0.15 12.4 9.8 0.29 11.5 9.8 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OIR57214.1 - 0.31 10.9 7.3 1.1 9.2 7.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR57214.1 - 0.99 9.2 8.1 1.8 8.4 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR57214.1 - 1.9 8.5 9.0 3.8 7.6 9.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OIR57214.1 - 4.1 7.4 9.1 10 6.1 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OIR57214.1 - 5 7.4 8.6 0.61 10.3 3.9 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SYCP2_SLD PF18584.1 OIR57216.1 - 0.43 10.8 2.4 0.45 10.7 0.1 2.2 3 0 0 3 3 3 0 Synaptonemal complex 2 Spt16M-like domain FHA_2 PF17913.1 OIR57217.1 - 8.7e-08 32.3 0.2 0.41 10.9 0.0 5.5 4 2 1 6 6 6 2 FHA domain zf-C3HC4_3 PF13920.6 OIR57217.1 - 0.0064 16.3 1.0 0.021 14.7 1.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR57217.1 - 0.011 16.0 2.6 0.051 13.9 2.6 2.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 OIR57217.1 - 0.014 15.2 1.0 0.047 13.5 1.0 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Spt4 PF06093.13 OIR57217.1 - 0.038 14.1 1.7 1.1 9.4 0.2 3.6 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger zf-RING_5 PF14634.6 OIR57217.1 - 0.044 13.8 3.0 0.15 12.0 3.0 2.0 1 0 0 1 1 1 0 zinc-RING finger domain YacG PF03884.14 OIR57217.1 - 0.089 12.5 0.1 16 5.3 0.0 3.8 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG MlaD PF02470.20 OIR57217.1 - 0.15 12.4 0.6 44 4.5 0.1 3.9 4 1 0 4 4 4 0 MlaD protein zf-C3HC4_4 PF15227.6 OIR57217.1 - 0.49 10.6 4.0 1.9 8.7 4.0 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2247 PF10004.9 OIR57217.1 - 0.67 9.7 11.2 9.7 5.9 0.1 4.2 2 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2247) Prok-RING_4 PF14447.6 OIR57217.1 - 0.93 9.4 6.0 1.7 8.6 3.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 TnpV PF14198.6 OIR57218.1 - 8.4e-05 22.5 0.6 5.3 7.1 0.0 4.6 3 1 1 4 4 4 1 Transposon-encoded protein TnpV zf-C3HC4_3 PF13920.6 OIR57218.1 - 0.00019 21.2 9.6 0.00019 21.2 9.6 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57218.1 - 0.0077 16.3 5.5 0.019 15.1 5.5 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger FYVE_2 PF02318.16 OIR57218.1 - 0.013 15.7 9.3 0.037 14.2 9.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger Reg_prop PF07494.11 OIR57218.1 - 0.041 14.1 1.8 68 4.2 0.0 4.7 5 0 0 5 5 5 0 Two component regulator propeller Zn_Tnp_IS1595 PF12760.7 OIR57218.1 - 0.14 12.2 0.9 0.28 11.2 0.2 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C3HC4_4 PF15227.6 OIR57218.1 - 1.4 9.1 5.2 4.4 7.5 5.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OIR57218.1 - 2.9 7.7 9.9 23 4.9 9.9 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OIR57218.1 - 3.2 8.1 8.0 4.3 7.7 2.4 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 OIR57218.1 - 4.2 7.5 7.6 19 5.3 7.2 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 OIR57218.1 - 4.8 7.2 8.5 15 5.6 8.6 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Rho_Binding PF08912.11 OIR57220.1 - 0.037 14.9 0.4 0.78 10.6 0.0 2.1 2 0 0 2 2 2 0 Rho Binding Ph1570 PF09638.10 OIR57221.1 - 0.027 14.3 0.3 0.057 13.3 0.2 1.6 1 1 1 2 2 2 0 Ph1570 protein zf-C3HC4_3 PF13920.6 OIR57222.1 - 2.1e-05 24.3 8.3 4.2e-05 23.3 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57222.1 - 0.00029 20.9 5.3 0.00068 19.7 5.3 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger Nucleic_acid_bd PF13820.6 OIR57222.1 - 0.0019 18.0 2.7 1.9 8.3 0.1 4.0 3 1 1 4 4 4 1 Putative nucleic acid-binding region FYVE_2 PF02318.16 OIR57222.1 - 0.083 13.1 7.1 0.18 12.0 7.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger NBD94 PF16830.5 OIR57222.1 - 0.2 12.1 1.7 0.38 11.2 0.2 2.3 2 1 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH zf-RING_UBOX PF13445.6 OIR57222.1 - 0.52 10.4 4.4 1.2 9.2 4.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OIR57222.1 - 0.55 10.4 5.6 2.5 8.3 5.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OIR57222.1 - 0.68 10.0 8.4 1.5 8.9 8.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2197 PF09963.9 OIR57222.1 - 1.4 9.2 7.5 4.6 7.6 7.4 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.7 OIR57222.1 - 1.8 8.7 6.5 21 5.2 7.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.6 OIR57222.1 - 1.8 8.4 13.1 11 6.0 9.7 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OIR57222.1 - 2.1 8.7 6.9 2.4 8.5 0.3 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 OIR57222.1 - 4.7 7.3 5.9 3 7.9 0.1 2.7 2 1 0 2 2 2 0 BED zinc finger zf-C3HC4 PF00097.25 OIR57222.1 - 7.5 6.5 8.8 19 5.2 8.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FHA_2 PF17913.1 OIR57223.1 - 0.011 16.0 0.1 69 3.8 0.0 4.4 3 1 1 4 4 4 0 FHA domain tRNA-synt_2b PF00587.25 OIR57224.1 - 0.082 12.9 0.0 0.12 12.4 0.0 1.2 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Cas9_a PF18470.1 OIR57227.1 - 0.0056 16.3 0.6 1.8 8.1 0.0 2.8 4 0 0 4 4 4 2 Cas9 alpha-helical lobe domain YacG PF03884.14 OIR57227.1 - 0.069 12.9 0.0 13 5.6 0.0 3.3 4 0 0 4 4 4 0 DNA gyrase inhibitor YacG Ist1 PF03398.14 OIR57227.1 - 0.082 12.8 2.4 1 9.3 0.3 2.7 2 1 1 3 3 3 0 Regulator of Vps4 activity in the MVB pathway DUF3540 PF12059.8 OIR57227.1 - 0.1 12.4 1.0 15 5.4 0.0 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3540) zf-CDGSH PF09360.10 OIR57227.1 - 2.3 8.5 3.7 1.6e+02 2.6 0.0 4.0 4 0 0 4 4 4 0 Iron-binding zinc finger CDGSH type Peptidase_M22 PF00814.25 OIR57230.1 - 4.6e-86 288.9 0.0 5.6e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 OIR57230.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Y_phosphatase PF00102.27 OIR57231.1 - 3.6e-64 216.5 0.1 4.6e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 OIR57231.1 - 0.00014 22.0 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OIR57231.1 - 0.00032 20.5 0.0 0.00077 19.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 OIR57231.1 - 0.0031 17.6 0.1 0.025 14.7 0.0 2.3 2 1 0 2 2 2 1 Inositol hexakisphosphate Adaptin_N PF01602.20 OIR57232.1 - 1.4e-43 149.3 0.0 1.9e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OIR57232.1 - 1.7e-15 57.4 0.0 3.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OIR57232.1 - 1.9e-05 24.8 0.0 4.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OIR57232.1 - 0.00032 21.0 0.6 0.74 10.2 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats SMC_hinge PF06470.13 OIR57232.1 - 0.01 16.2 0.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain Ipi1_N PF12333.8 OIR57232.1 - 0.13 12.9 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Cornichon PF03311.14 OIR57234.1 - 3.5e-33 114.5 7.8 4.3e-33 114.2 7.8 1.0 1 0 0 1 1 1 1 Cornichon protein Proteasome PF00227.26 OIR57236.1 - 3.5e-34 117.9 0.1 4.1e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit TIG PF01833.24 OIR57236.1 - 0.12 12.5 0.0 3.4 7.8 0.0 2.2 1 1 1 2 2 2 0 IPT/TIG domain Proteasome PF00227.26 OIR57237.1 - 3.4e-45 153.9 0.7 3.9e-45 153.7 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit IDH PF03971.14 OIR57238.1 - 0.021 13.3 0.1 0.025 13.1 0.1 1.0 1 0 0 1 1 1 0 Monomeric isocitrate dehydrogenase COX4 PF02936.14 OIR57240.1 - 0.014 15.4 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Bro-N PF02498.17 OIR57240.1 - 0.027 15.1 0.2 0.059 14.1 0.2 1.6 1 0 0 1 1 1 0 BRO family, N-terminal domain DUF4647 PF15504.6 OIR57240.1 - 0.082 12.0 0.0 0.17 11.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Pkinase PF00069.25 OIR57242.1 - 1.1e-10 41.3 0.0 1.4e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57242.1 - 0.012 14.9 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 OIR57244.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57244.1 - 0.0064 15.8 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OIR57245.1 - 2.7e-32 112.2 0.0 3.9e-32 111.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57245.1 - 4.8e-17 62.1 0.0 6.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57245.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Not1 PF04054.15 OIR57245.1 - 0.048 12.6 0.1 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 CBFD_NFYB_HMF PF00808.23 OIR57246.1 - 2e-12 47.2 0.1 2.4e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OIR57246.1 - 9e-07 29.3 0.1 1.1e-06 29.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 OIR57246.1 - 0.13 12.8 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A GTP_EFTU PF00009.27 OIR57247.1 - 1.2e-64 217.4 0.1 1.7e-64 217.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OIR57247.1 - 2.8e-27 94.9 0.0 8.9e-27 93.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 OIR57247.1 - 8.2e-22 77.1 0.0 4.7e-21 74.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OIR57247.1 - 1e-11 45.0 0.1 2.5e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OIR57247.1 - 1.1e-11 44.7 0.0 2.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OIR57247.1 - 0.00029 20.9 0.1 0.0014 18.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 OIR57247.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Roc PF08477.13 OIR57247.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 OIR57248.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.6 1 1 1 2 2 2 0 Protein kinase domain Ribosomal_L1 PF00687.21 OIR57249.1 - 4.9e-29 101.5 0.0 6.4e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TadZ_N PF16968.5 OIR57251.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Pkinase PF00069.25 OIR57252.1 - 4.6e-35 121.3 0.1 1.3e-34 119.8 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57252.1 - 6.7e-18 64.9 0.0 1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57252.1 - 2.2e-09 37.0 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR57252.1 - 0.0037 16.3 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OIR57252.1 - 0.01 15.5 0.1 3.8 7.1 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OIR57252.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR57252.1 - 0.15 11.4 0.0 0.46 9.7 0.0 1.7 1 1 1 2 2 2 0 Kinase-like Arm PF00514.23 OIR57252.1 - 0.2 11.8 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Homeodomain PF00046.29 OIR57253.1 - 7.2e-10 38.6 0.6 7.2e-10 38.6 0.6 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 OIR57253.1 - 0.00024 20.9 0.0 0.00074 19.4 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 OIR57253.1 - 0.00085 18.7 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Polyoma_coat2 PF00761.20 OIR57253.1 - 0.21 11.3 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein AAA PF00004.29 OIR57254.1 - 1.4e-41 142.0 0.0 2.8e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR57254.1 - 7.1e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 OIR57254.1 - 2e-05 24.9 0.0 0.005 17.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 OIR57254.1 - 2.2e-05 24.9 0.0 0.0018 18.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OIR57254.1 - 7.7e-05 22.7 0.0 0.00035 20.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OIR57254.1 - 0.00053 19.2 0.0 0.00094 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OIR57254.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OIR57254.1 - 0.0039 17.3 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 OIR57254.1 - 0.011 16.2 0.0 0.065 13.6 0.0 2.3 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.6 OIR57254.1 - 0.013 15.6 0.0 0.041 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OIR57254.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OIR57254.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 OIR57254.1 - 0.026 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OIR57254.1 - 0.035 13.8 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OIR57254.1 - 0.04 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OIR57254.1 - 0.042 13.2 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OIR57254.1 - 0.059 13.9 0.0 0.19 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 OIR57254.1 - 0.086 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Roc PF08477.13 OIR57254.1 - 0.099 12.9 0.0 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 OIR57254.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OIR57254.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 OIR57254.1 - 0.11 12.4 0.1 3.7 7.4 0.0 2.6 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 OIR57254.1 - 0.14 12.0 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OIR57254.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 OIR57254.1 - 0.19 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 OIR57254.1 - 0.19 11.4 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 OIR57255.1 - 1.1e-16 61.0 0.0 4.2e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OIR57255.1 - 7.5e-09 35.2 0.0 1.1e-05 24.8 0.0 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OIR57255.1 - 3.9e-08 33.7 0.1 0.0021 18.4 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OIR57255.1 - 7.5e-07 29.3 0.1 5.4e-05 23.2 0.0 3.1 2 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OIR57255.1 - 7.6e-07 28.7 0.9 0.016 14.5 0.2 3.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OIR57255.1 - 5.3e-06 26.6 0.0 2.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OIR57255.1 - 0.00048 20.6 0.4 0.11 13.1 0.2 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OIR57255.1 - 0.00061 19.5 0.1 0.48 10.0 0.0 3.6 2 2 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OIR57255.1 - 0.002 17.4 0.1 0.19 10.9 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 OIR57255.1 - 0.0071 15.6 0.6 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OIR57255.1 - 0.011 14.9 0.1 0.096 11.7 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.17 OIR57255.1 - 0.011 16.3 0.1 3.8 8.2 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.14 OIR57255.1 - 0.014 14.1 0.2 0.22 10.2 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 OIR57255.1 - 0.052 13.8 0.0 7.6 6.8 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 OIR57255.1 - 0.067 12.5 0.1 4.5 6.6 0.0 2.5 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TMEM208_SND2 PF05620.11 OIR57256.1 - 6.8e-11 42.2 5.3 1.1e-10 41.6 5.3 1.3 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Tcp11 PF05794.13 OIR57257.1 - 4e-19 69.0 1.3 1.7e-08 34.0 0.0 4.0 2 1 1 3 3 3 3 T-complex protein 11 FHA_2 PF17913.1 OIR57259.1 - 0.037 14.3 0.0 13 6.1 0.0 4.4 5 0 0 5 5 5 0 FHA domain DUF2839 PF10999.8 OIR57259.1 - 0.072 13.5 1.4 16 6.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) PGP_phosphatase PF09419.10 OIR57259.1 - 0.095 12.3 0.0 24 4.5 0.0 2.9 1 1 2 3 3 3 0 Mitochondrial PGP phosphatase Prok-TraM PF09228.10 OIR57259.1 - 0.91 9.9 4.1 14 6.1 0.7 3.4 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM zf-C3HC4_3 PF13920.6 OIR57260.1 - 5.5e-05 22.9 4.1 0.00011 22.0 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3929 PF13066.6 OIR57260.1 - 0.013 15.5 0.6 0.082 13.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) zf-RING_2 PF13639.6 OIR57260.1 - 0.025 14.9 6.7 0.078 13.3 6.7 1.9 1 0 0 1 1 1 0 Ring finger domain Reovirus_M2 PF05993.12 OIR57260.1 - 0.21 9.7 0.0 0.32 9.1 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) zf-RING_4 PF14570.6 OIR57260.1 - 0.23 11.3 4.9 0.54 10.1 4.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OIR57260.1 - 0.3 11.4 2.2 0.73 10.2 2.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OIR57260.1 - 0.35 10.8 6.9 0.56 10.1 3.8 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OIR57260.1 - 0.61 10.1 5.6 1.5 8.8 5.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Zf_RING PF16744.5 OIR57260.1 - 2.4 8.4 7.0 1.8 8.8 4.1 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger FYVE_2 PF02318.16 OIR57260.1 - 5.2 7.3 12.1 0.1 12.8 3.1 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger DUF2098 PF09871.9 OIR57261.1 - 7.3 7.0 6.2 1.4 9.3 0.2 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) QSOX_Trx1 PF18108.1 OIR57264.1 - 0.14 12.4 3.7 3.9 7.7 0.2 3.2 1 1 2 3 3 3 0 QSOX Trx-like domain Borrelia_P83 PF05262.11 OIR57265.1 - 4 5.8 16.0 4.4 5.7 16.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Exo_endo_phos PF03372.23 OIR57266.1 - 0.00019 21.0 0.0 0.00021 20.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Helicase_C PF00271.31 OIR57267.1 - 1e-11 45.1 0.0 3.1e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OIR57267.1 - 6.6e-07 29.2 0.1 2e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OIR57267.1 - 0.00053 20.0 0.1 0.014 15.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 OIR57267.1 - 0.034 14.1 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain SPICE PF15678.5 OIR57267.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Shugoshin_N PF07558.11 OIR57268.1 - 0.066 13.1 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region 8TM_micro PF17028.5 OIR57270.1 - 0.13 12.0 0.1 0.15 11.7 0.1 1.0 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain SVIP PF15811.5 OIR57271.1 - 0.018 15.5 2.8 0.64 10.5 0.0 2.5 3 0 0 3 3 3 0 Small VCP/p97-interacting protein Pkinase PF00069.25 OIR57272.1 - 1e-52 179.1 0.0 3.8e-48 164.2 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57272.1 - 1.3e-29 103.3 0.1 8.2e-20 71.2 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase RWD PF05773.22 OIR57272.1 - 0.00089 19.5 0.2 0.0024 18.1 0.2 1.7 1 0 0 1 1 1 1 RWD domain APH PF01636.23 OIR57272.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR57272.1 - 0.033 13.5 0.0 0.86 8.9 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 OIR57272.1 - 0.11 11.9 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_Tnp_Tc3_2 PF01498.18 OIR57272.1 - 0.14 12.5 0.2 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Transposase PAPA-1 PF04795.12 OIR57273.1 - 0.083 13.7 13.7 0.12 13.1 13.7 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region LRR_4 PF12799.7 OIR57274.1 - 0.0034 17.7 0.0 0.61 10.6 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF1569 PF07606.11 OIR57274.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) FA_FANCE PF11510.8 OIR57275.1 - 0.076 12.4 0.1 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Fanconi Anaemia group E protein FANCE Ribosomal_L10 PF00466.20 OIR57276.1 - 5.5e-20 71.4 0.5 1.3e-19 70.2 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 OIR57276.1 - 2.5e-18 65.8 0.2 5.2e-18 64.8 0.2 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 OIR57276.1 - 1.3e-06 28.8 18.4 8.5e-06 26.3 18.3 2.3 1 1 0 1 1 1 1 60s Acidic ribosomal protein CAS_CSE1 PF03378.15 OIR57277.1 - 0.12 10.9 0.1 0.42 9.0 0.0 2.0 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus PAP_central PF04928.17 OIR57278.1 - 3.8e-95 317.6 0.0 5e-95 317.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OIR57278.1 - 2.3e-23 82.7 0.0 4.4e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OIR57278.1 - 1.5e-09 38.0 0.0 4.4e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 OIR57278.1 - 0.0051 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm Fer4_19 PF06902.11 OIR57279.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Alg14 PF08660.11 OIR57280.1 - 1e-20 74.4 5.9 3.9e-17 62.7 0.1 2.9 1 1 2 3 3 3 2 Oligosaccharide biosynthesis protein Alg14 like Pkinase PF00069.25 OIR57281.1 - 4.6e-63 213.0 0.0 5.9e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57281.1 - 1.7e-33 116.1 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OIR57281.1 - 1.8e-14 53.7 0.0 6.8e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 POLO box duplicated region APH PF01636.23 OIR57281.1 - 6.8e-06 26.2 0.1 0.027 14.4 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR57281.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 OIR57281.1 - 0.0014 18.3 0.1 1 8.9 0.0 2.7 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OIR57281.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4520 PF15016.6 OIR57281.1 - 0.0045 17.0 0.9 2.6 8.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) RIO1 PF01163.22 OIR57281.1 - 0.016 14.8 0.0 0.043 13.4 0.0 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OIR57281.1 - 0.082 11.8 0.0 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain DUF4524 PF15025.6 OIR57281.1 - 0.14 11.9 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) Acyltransferase PF01553.21 OIR57282.1 - 3.6e-16 59.0 0.0 5.2e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pribosyltran PF00156.27 OIR57282.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Cnn_1N PF07989.11 OIR57284.1 - 1.7e-17 63.3 4.1 1.7e-17 63.3 4.1 9.2 2 2 6 8 8 8 1 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 OIR57284.1 - 0.0078 16.4 5.5 0.0078 16.4 5.5 8.3 1 1 6 8 8 8 2 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 OIR57284.1 - 0.45 10.8 0.0 0.45 10.8 0.0 8.2 9 0 0 9 9 9 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 OIR57284.1 - 0.64 10.2 96.3 0.2 11.8 10.5 6.8 2 2 3 6 6 6 0 Tropomyosin like HOOK PF05622.12 OIR57284.1 - 1.1 7.3 80.5 0.25 9.5 48.2 3.1 1 1 1 3 3 3 0 HOOK protein UQ_con PF00179.26 OIR57285.1 - 1.3e-51 173.9 0.0 1.5e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57285.1 - 0.068 12.9 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B AA_permease_2 PF13520.6 OIR57286.1 - 5.2e-53 180.4 44.2 5.9e-53 180.2 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OIR57286.1 - 3.6e-28 98.4 39.9 8.3e-28 97.2 39.9 1.5 1 1 0 1 1 1 1 Amino acid permease DUF1453 PF07301.11 OIR57286.1 - 0.00091 19.3 1.1 0.00091 19.3 1.1 3.7 3 2 2 5 5 5 1 Protein of unknown function (DUF1453) LRR_6 PF13516.6 OIR57287.1 - 1.1e-13 50.1 0.2 0.0046 16.9 0.5 6.5 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 OIR57287.1 - 4.2e-08 33.3 0.1 0.19 12.2 0.0 5.3 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OIR57287.1 - 1.7e-07 30.8 1.7 13 6.8 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 OIR57287.1 - 0.0002 21.0 0.7 3.8 7.3 0.0 5.3 5 1 0 5 5 5 1 Leucine rich repeat XPG_N PF00752.17 OIR57289.1 - 8.2e-25 87.2 0.0 2.4e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 OIR57289.1 - 5.8e-22 77.9 1.1 1.2e-21 76.9 0.4 1.9 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 OIR57289.1 - 3.7e-05 23.3 0.0 6.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OIR57289.1 - 0.00023 21.7 0.0 0.00052 20.6 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold eIF-5_eIF-2B PF01873.17 OIR57290.1 - 9.4e-37 125.5 3.8 1.7e-36 124.6 3.8 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OIR57290.1 - 0.0068 15.9 0.6 0.015 14.8 0.6 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IreB PF06135.12 OIR57290.1 - 0.11 12.8 0.6 0.27 11.4 0.1 2.0 2 0 0 2 2 2 0 IreB regulatory phosphoprotein Cytochrom_c3_2 PF14537.6 OIR57290.1 - 0.13 12.7 1.0 0.3 11.6 0.3 2.0 2 0 0 2 2 2 0 Cytochrome c3 Lar_restr_allev PF14354.6 OIR57290.1 - 0.14 12.5 1.3 7.9 6.9 0.1 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF1764 PF08576.10 OIR57290.1 - 3.4 8.6 10.9 6.2e+02 1.4 10.9 2.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) tRNA-synt_2c PF01411.19 OIR57292.1 - 1.6e-16 59.9 0.0 2.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OIR57292.1 - 6.1e-06 26.2 0.9 1.2e-05 25.3 0.9 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PP2C PF00481.21 OIR57293.1 - 7.5e-40 137.2 0.0 9.1e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Thioredoxin PF00085.20 OIR57294.1 - 0.0019 18.1 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Soyouz_module PF14313.6 OIR57294.1 - 0.079 12.8 0.3 0.22 11.3 0.2 1.8 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DUF3626 PF12294.8 OIR57294.1 - 0.092 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) MNR PF15718.5 OIR57294.1 - 0.11 10.6 0.8 0.13 10.3 0.8 1.0 1 0 0 1 1 1 0 Protein moonraker RGS PF00615.19 OIR57295.1 - 5.6e-13 49.2 0.5 1.4e-12 47.9 0.5 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ndc80_HEC PF03801.13 OIR57295.1 - 0.1 12.2 0.4 0.18 11.5 0.4 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family RGS-like PF09128.11 OIR57295.1 - 0.45 10.2 4.4 0.13 11.9 0.8 2.1 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain MOZ_SAS PF01853.18 OIR57296.1 - 6.1e-66 221.5 0.0 9.5e-66 220.9 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OIR57296.1 - 1.1e-20 73.0 1.5 1.9e-20 72.2 1.5 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OIR57296.1 - 5e-10 39.1 0.1 5e-10 39.1 0.1 2.1 3 0 0 3 3 3 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 OIR57296.1 - 1.1e-05 25.6 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OIR57296.1 - 2.8e-05 24.4 0.0 6.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OIR57296.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S10 PF00338.22 OIR57297.1 - 8.3e-13 48.4 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CBFD_NFYB_HMF PF00808.23 OIR57298.1 - 2e-15 56.8 1.4 2.7e-15 56.4 0.0 1.9 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 OIR57298.1 - 0.00039 20.4 0.1 0.0036 17.3 0.0 2.1 1 1 1 2 2 2 1 Bromodomain associated Histone PF00125.24 OIR57298.1 - 0.0042 17.4 0.4 0.023 15.1 0.0 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Sel1 PF08238.12 OIR57299.1 - 1.4e-62 206.7 37.5 1.3e-08 35.3 0.0 14.8 16 0 0 16 16 16 11 Sel1 repeat TPR_17 PF13431.6 OIR57299.1 - 0.011 16.1 0.0 13 6.4 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OIR57299.1 - 0.16 12.9 0.7 12 7.1 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OIR57299.1 - 0.66 9.7 3.7 16 5.3 0.0 4.6 5 0 0 5 5 5 0 TPR repeat Actin PF00022.19 OIR57300.1 - 5.7e-08 31.8 0.2 0.0046 15.6 0.0 2.1 1 1 1 2 2 2 2 Actin Actin_micro PF17003.5 OIR57300.1 - 0.00065 19.0 0.1 0.00065 19.0 0.1 1.6 2 0 0 2 2 2 1 Putative actin-like family DNA_pol_E_B PF04042.16 OIR57303.1 - 9.1e-17 61.1 0.0 2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CENP-C_C PF11699.8 OIR57305.1 - 8.1e-14 51.6 0.0 1.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 OIR57305.1 - 3.8e-07 29.7 0.0 9.8e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 Cupin domain PcfK PF14058.6 OIR57305.1 - 0.019 15.2 4.3 0.69 10.2 0.1 2.3 2 0 0 2 2 2 0 PcfK-like protein AraC_binding PF02311.19 OIR57305.1 - 0.05 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain RB_B PF01857.20 OIR57308.1 - 0.17 11.9 0.7 0.27 11.3 0.2 1.6 1 1 0 2 2 2 0 Retinoblastoma-associated protein B domain 4HPAD_g_N PF18671.1 OIR57308.1 - 0.23 11.2 2.2 0.84 9.4 0.2 2.7 3 0 0 3 3 3 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal YpmT PF17431.2 OIR57308.1 - 0.31 11.1 1.2 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized YmpT-like CTP_transf_like PF01467.26 OIR57309.1 - 2.1e-31 109.1 0.1 3.6e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 OIR57309.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 FAD synthetase DUF3899 PF13038.6 OIR57309.1 - 0.075 13.5 0.6 0.59 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF1837 PF08878.11 OIR57310.1 - 0.046 13.5 0.2 0.072 12.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1837) DUF4834 PF16118.5 OIR57311.1 - 0.0098 16.8 14.9 0.56 11.2 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4834) Pfg27 PF09216.10 OIR57312.1 - 0.084 12.7 1.7 0.17 11.7 1.0 1.8 1 1 1 2 2 2 0 Pfg27 Sec63 PF02889.16 OIR57313.1 - 2.4e-13 49.8 2.8 5.5e-13 48.7 0.1 2.4 2 0 0 2 2 2 1 Sec63 Brl domain Helicase_C PF00271.31 OIR57313.1 - 0.018 15.4 4.0 0.27 11.6 0.1 3.4 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DUF4332 PF14229.6 OIR57313.1 - 0.02 15.1 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Cpn60_TCP1 PF00118.24 OIR57314.1 - 5.7e-157 523.3 2.3 7.1e-157 522.9 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3929 PF13066.6 OIR57316.1 - 0.039 14.0 1.9 0.15 12.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) NCD3G PF07562.14 OIR57316.1 - 2 8.5 6.3 1.5 8.9 3.8 2.0 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR FANCL_C PF11793.8 OIR57317.1 - 0.017 15.3 0.3 7 6.9 0.0 2.6 3 0 0 3 3 3 0 FANCL C-terminal domain FHA_2 PF17913.1 OIR57317.1 - 0.073 13.3 0.1 3.8 7.8 0.0 2.5 2 1 0 2 2 2 0 FHA domain DUF2110 PF09883.9 OIR57317.1 - 0.075 12.6 0.0 7.6 6.1 0.0 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2110) MlaD PF02470.20 OIR57317.1 - 0.1 12.9 0.0 22 5.4 0.0 2.4 2 1 0 2 2 2 0 MlaD protein NARG2_C PF10505.9 OIR57317.1 - 0.1 12.1 0.7 0.88 9.1 0.3 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Alpha_adaptin_C PF02296.16 OIR57320.1 - 0.046 13.9 0.1 2 8.6 0.0 2.6 2 1 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain Hexapep PF00132.24 OIR57322.1 - 0.17 11.7 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) Unpaired PF15972.5 OIR57323.1 - 0.66 9.5 4.9 0.78 9.2 0.0 3.1 3 1 1 4 4 4 0 Unpaired protein D5_N PF08706.11 OIR57323.1 - 3.5 7.9 5.1 4.9 7.4 3.8 1.9 2 0 0 2 2 2 0 D5 N terminal like zf-C3HC4_3 PF13920.6 OIR57324.1 - 0.00036 20.3 1.1 0.00052 19.8 1.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57324.1 - 0.037 14.1 0.9 0.06 13.5 0.9 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_2 PF13639.6 OIR57324.1 - 0.23 11.8 2.2 0.35 11.3 2.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OIR57325.1 - 0.1 12.6 2.0 0.25 11.3 2.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OIR57326.1 - 0.077 12.9 8.1 0.04 13.8 5.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1 PF00133.22 OIR57327.1 - 1.9e-47 161.9 0.0 1e-38 133.0 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OIR57327.1 - 9.9e-20 70.6 0.0 1.8e-10 40.2 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OIR57327.1 - 5e-14 52.5 0.0 9.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OIR57327.1 - 5.5e-08 32.5 0.0 9.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 OIR57327.1 - 0.055 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) DotU PF09850.9 OIR57329.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system protein DotU UCH PF00443.29 OIR57330.1 - 2.2e-39 135.5 1.2 7.8e-39 133.7 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR57330.1 - 9.3e-21 74.7 0.8 3.6e-11 43.2 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C14 PF00656.22 OIR57331.1 - 0.08 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Caspase domain CryBP1 PF07029.11 OIR57331.1 - 0.11 12.5 1.3 11 6.1 0.1 2.6 2 1 0 2 2 2 0 CryBP1 protein YhcG_C PF06250.11 OIR57331.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain zf-C3HC4_3 PF13920.6 OIR57333.1 - 0.028 14.3 4.8 0.066 13.1 4.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHM7_ext PF12621.8 OIR57333.1 - 0.031 14.4 1.0 17 5.7 0.0 4.5 4 1 0 5 5 5 0 Extracellular tail, of 10TM putative phosphate transporter PPP1R32 PF15691.5 OIR57333.1 - 0.15 11.1 0.0 1.9 7.5 0.0 2.5 2 1 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 32 GUCT PF08152.12 OIR57333.1 - 0.3 11.4 1.3 69 3.8 0.1 3.8 3 0 0 3 3 3 0 GUCT (NUC152) domain Mog1 PF04603.12 OIR57334.1 - 2.4e-17 63.6 0.1 4.9e-17 62.6 0.1 1.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein zf-HIT PF04438.16 OIR57339.1 - 2.7e-08 33.6 8.1 6e-08 32.4 8.1 1.6 1 0 0 1 1 1 1 HIT zinc finger MCM6_C PF18263.1 OIR57341.1 - 4.2e-06 26.9 0.1 6.8e-06 26.3 0.1 1.3 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain AAA PF00004.29 OIR57342.1 - 1e-09 38.9 0.0 1.7e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OIR57342.1 - 2.8e-09 37.6 0.4 6.6e-08 33.1 0.2 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OIR57342.1 - 1.1e-07 32.1 0.1 3.6e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OIR57342.1 - 0.00069 19.4 0.1 0.0016 18.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OIR57342.1 - 0.0023 18.3 0.3 0.016 15.5 0.1 2.0 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 OIR57342.1 - 0.0044 17.0 0.3 0.02 14.8 0.1 1.9 1 1 1 2 2 2 1 NTPase T2SSE PF00437.20 OIR57342.1 - 0.0087 15.1 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MeaB PF03308.16 OIR57342.1 - 0.013 14.5 0.1 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_6 PF12774.7 OIR57342.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_11 PF13086.6 OIR57342.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 OIR57342.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_32 PF13654.6 OIR57342.1 - 0.09 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OIR57342.1 - 0.094 12.7 0.0 0.43 10.6 0.1 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OIR57342.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OIR57342.1 - 0.14 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OIR57342.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GvpD PF07088.11 OIR57342.1 - 0.16 10.5 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein MIF4G PF02854.19 OIR57343.1 - 9e-15 54.9 1.2 9.8e-15 54.8 0.1 1.6 2 0 0 2 2 2 1 MIF4G domain DUF1664 PF07889.12 OIR57343.1 - 0.0016 18.5 0.7 0.0034 17.4 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) MA3 PF02847.17 OIR57343.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 MA3 domain FAM76 PF16046.5 OIR57345.1 - 0.017 14.5 3.0 0.02 14.2 3.0 1.1 1 0 0 1 1 1 0 FAM76 protein WH2 PF02205.20 OIR57345.1 - 0.13 12.2 0.7 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 WH2 motif Presenilin PF01080.17 OIR57345.1 - 1 8.0 2.5 1.1 7.9 2.5 1.1 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 OIR57346.1 - 1.2e-65 221.5 0.0 1.8e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57346.1 - 2.9e-43 148.0 0.0 5e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 OIR57346.1 - 7.7e-11 41.7 26.2 5.8e-07 29.3 3.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OIR57346.1 - 2.4e-05 25.0 4.1 5.6e-05 23.8 4.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 OIR57346.1 - 0.00014 21.9 8.6 0.051 13.7 0.5 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_2 PF03107.16 OIR57346.1 - 0.00082 19.6 23.1 0.078 13.3 0.7 2.5 2 0 0 2 2 2 2 C1 domain PHD_2 PF13831.6 OIR57346.1 - 3.7 7.2 16.9 3.2 7.4 4.9 2.7 2 0 0 2 2 2 0 PHD-finger Cofilin_ADF PF00241.20 OIR57347.1 - 7.1e-38 129.1 1.0 8.2e-38 128.9 1.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2004 PF09406.10 OIR57347.1 - 0.028 14.7 0.1 0.067 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) Sec63 PF02889.16 OIR57348.1 - 1.4e-31 109.6 0.0 2.4e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OIR57348.1 - 2.3e-28 99.1 0.1 1.1e-27 96.9 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OIR57348.1 - 1.7e-12 47.6 0.0 1e-11 45.1 0.0 2.1 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OIR57348.1 - 5.1e-06 26.8 0.0 2.5e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OIR57348.1 - 8.7e-05 22.3 0.2 0.00022 21.0 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OIR57348.1 - 0.00038 20.8 1.1 0.014 15.7 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 OIR57348.1 - 0.001 19.3 0.4 0.014 15.7 0.4 2.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OIR57348.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OIR57348.1 - 0.028 14.8 0.6 0.12 12.7 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 OIR57348.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 OIR57348.1 - 0.069 12.9 1.3 0.12 12.1 0.0 1.8 2 1 1 3 3 3 0 AAA domain DUF383 PF04063.14 OIR57348.1 - 0.12 12.1 0.2 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF383) SLM4 PF16818.5 OIR57349.1 - 0.021 14.8 0.3 0.05 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein SLM4 Nic96 PF04097.14 OIR57351.1 - 9.2e-76 255.6 0.0 2.8e-74 250.7 0.0 2.3 1 1 0 1 1 1 1 Nup93/Nic96 Pkinase PF00069.25 OIR57352.1 - 1.9e-35 122.5 0.0 2.1e-33 115.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57352.1 - 1.7e-20 73.4 0.0 2.9e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR57352.1 - 0.0013 18.8 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR57352.1 - 0.0038 16.6 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4122 PF13498.6 OIR57352.1 - 0.01 15.6 0.0 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4122) Haspin_kinase PF12330.8 OIR57352.1 - 0.011 14.7 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 OIR57352.1 - 0.016 14.8 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 OIR57352.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH_6_hur PF04655.14 OIR57352.1 - 0.084 12.2 0.7 6.5 6.1 0.1 2.4 2 1 1 3 3 3 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase SWIRM PF04433.17 OIR57354.1 - 5.9e-22 77.8 0.0 5.9e-22 77.8 0.0 2.1 3 0 0 3 3 3 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OIR57354.1 - 6.4e-18 64.5 8.3 1.9e-17 63.0 8.3 1.9 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OIR57354.1 - 1.3e-09 38.1 0.3 2.8e-09 37.0 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR57354.1 - 2.2e-05 24.6 0.1 5.4e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 OIR57354.1 - 0.0019 17.9 1.8 0.0032 17.2 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM-assoc_3 PF16498.5 OIR57354.1 - 0.042 14.1 0.4 0.042 14.1 0.4 2.2 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal Ribosomal_L18 PF17135.4 OIR57355.1 - 4e-49 166.5 1.8 4.8e-49 166.3 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OIR57355.1 - 0.0012 19.5 0.1 0.0033 18.1 0.1 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_A_bac PF01000.26 OIR57356.1 - 1.9e-31 108.7 0.0 2.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OIR57356.1 - 1e-18 66.5 0.0 1.4e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HC2 PF07382.11 OIR57357.1 - 1.5e-09 38.3 25.3 2.3e-09 37.6 25.3 1.3 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 hDGE_amylase PF14701.6 OIR57357.1 - 2.7 7.0 8.0 3.5 6.6 8.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain RR_TM4-6 PF06459.12 OIR57357.1 - 5.4 6.8 21.2 8.4 6.1 21.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 OIR57358.1 - 8e-29 99.3 0.2 1.1e-14 54.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OIR57358.1 - 3.5e-05 23.6 0.0 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 OIR57358.1 - 0.0012 18.5 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 OIR57358.1 - 0.0054 16.9 0.0 3.1 8.1 0.0 2.2 2 0 0 2 2 2 2 BRCA1-associated protein 2 PHM7_cyt PF14703.6 OIR57358.1 - 0.0095 16.2 0.1 0.67 10.2 0.0 2.5 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter DUF5514 PF17633.2 OIR57358.1 - 0.019 15.2 0.7 0.049 13.9 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5514) RRM_Rrp7 PF17799.1 OIR57358.1 - 0.057 13.2 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF4907 PF16250.5 OIR57358.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) GluRS_N PF18466.1 OIR57358.1 - 0.18 12.3 1.7 20 5.7 0.3 2.5 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain CooT PF10133.9 OIR57359.1 - 0.11 12.7 0.1 2.2 8.6 0.0 3.2 5 0 0 5 5 5 0 CO dehydrogenase accessory protein CooT TPT PF03151.16 OIR57360.1 - 7.4e-13 48.5 17.8 1.2e-12 47.8 17.8 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OIR57360.1 - 2.1e-10 40.9 27.6 4.6e-09 36.6 10.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 OIR57360.1 - 0.025 15.2 0.7 0.025 15.2 0.7 3.2 2 1 0 3 3 3 0 Small Multidrug Resistance protein EF1G PF00647.19 OIR57363.1 - 6.5e-37 125.9 0.0 1.2e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 OIR57363.1 - 5.6e-07 29.7 0.3 2.1e-06 27.9 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OIR57363.1 - 1.3e-06 28.5 0.1 3.2e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OIR57363.1 - 3.5e-05 23.7 0.7 0.00027 20.9 0.7 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OIR57363.1 - 0.0052 16.6 0.1 0.019 14.7 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sep15_SelM PF08806.11 OIR57364.1 - 5.6e-08 32.8 7.4 1.1 9.5 0.1 6.2 6 0 0 6 6 6 2 Sep15/SelM redox domain zf-C3HC4_3 PF13920.6 OIR57364.1 - 0.00013 21.8 3.4 0.00024 20.9 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Eco57I PF07669.11 OIR57364.1 - 0.00016 22.1 1.5 1.5 9.4 0.0 4.6 2 2 3 5 5 5 2 Eco57I restriction-modification methylase ECSIT PF06239.11 OIR57364.1 - 0.00092 18.4 0.5 1.1 8.3 0.0 4.2 3 2 2 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway EIF_2_alpha PF07541.12 OIR57364.1 - 0.0037 17.4 6.7 16 5.6 0.0 4.8 5 0 0 5 5 5 1 Eukaryotic translation initiation factor 2 alpha subunit TbpB_C PF17483.2 OIR57364.1 - 0.0051 17.2 0.8 2.9 8.3 0.0 3.2 1 1 1 3 3 3 1 C-lobe handle domain of Tf-binding protein B TMEM191C PF15194.6 OIR57364.1 - 0.07 13.3 0.0 52 4.0 0.0 4.1 5 0 0 5 5 5 0 TMEM191C family ANAPC15 PF15243.6 OIR57364.1 - 0.074 13.5 6.9 44 4.6 0.1 4.9 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 15 zf-C3HC4_5 PF17121.5 OIR57364.1 - 1.6 8.6 4.6 2.9 7.9 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UCH PF00443.29 OIR57365.1 - 3.1e-26 92.4 1.5 8.9e-26 90.9 1.5 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR57365.1 - 0.00036 20.2 9.9 0.00066 19.4 0.0 3.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UQ_con PF00179.26 OIR57366.1 - 5.7e-42 142.7 0.0 6.4e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57366.1 - 2.8e-06 27.1 0.0 3.3e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 OIR57366.1 - 0.0032 17.1 0.1 0.0054 16.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 AnfG_VnfG PF03139.15 OIR57366.1 - 0.041 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit Ribonuc_red_lgC PF02867.15 OIR57367.1 - 1.4e-13 50.2 0.1 1.7e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Med21 PF11221.8 OIR57368.1 - 0.039 14.2 0.0 0.45 10.7 0.0 2.0 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF2935 PF11155.8 OIR57368.1 - 0.13 12.6 0.1 0.17 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) SMC_N PF02463.19 OIR57369.1 - 3.6e-61 206.4 15.1 1.4e-60 204.5 15.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OIR57369.1 - 4.1e-22 78.7 0.0 1.2e-21 77.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OIR57369.1 - 1.1e-09 38.5 9.4 9.8e-06 25.6 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OIR57369.1 - 3e-06 26.9 0.0 5.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OIR57369.1 - 5.4e-05 23.8 39.9 5.4e-05 23.8 39.9 6.2 2 2 2 4 4 4 1 AAA domain AAA_22 PF13401.6 OIR57369.1 - 0.052 13.8 0.0 14 6.0 0.0 3.9 3 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 OIR57369.1 - 0.2 12.2 0.0 0.2 12.2 0.0 6.0 3 2 1 4 4 4 0 ABC transporter WD40 PF00400.32 OIR57370.1 - 1e-27 95.8 18.9 5.9e-05 23.8 0.0 10.1 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57370.1 - 2.8e-13 50.0 7.2 0.22 11.9 0.0 8.1 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OIR57370.1 - 4.8e-07 29.4 3.9 0.57 9.5 0.0 4.6 3 2 1 4 4 4 4 WD40-like domain Utp12 PF04003.12 OIR57370.1 - 6.3e-06 26.5 1.7 1.2e-05 25.6 1.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PQQ_2 PF13360.6 OIR57370.1 - 0.00025 20.7 0.7 0.12 12.0 0.0 3.2 2 1 0 2 2 2 1 PQQ-like domain RAB3GAP2_N PF14655.6 OIR57370.1 - 0.015 14.6 0.3 2.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 OIR57370.1 - 0.015 14.0 2.5 3.8 6.0 0.1 4.3 3 2 0 4 4 4 0 Nucleoporin Nup120/160 PQQ PF01011.21 OIR57370.1 - 0.088 12.8 0.0 0.79 9.8 0.1 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat Mcl1_mid PF12341.8 OIR57370.1 - 0.092 12.1 0.4 0.67 9.2 0.0 2.5 3 0 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region DUF5046 PF16465.5 OIR57370.1 - 0.14 11.5 0.2 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) AGOG PF09171.10 OIR57370.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 N-glycosylase/DNA lyase GDA1_CD39 PF01150.17 OIR57371.1 - 4.7e-38 130.9 0.0 1.3e-36 126.2 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Sec2p PF06428.11 OIR57372.1 - 2.2e-10 40.4 16.1 2.4e-10 40.2 14.8 1.7 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p CENP-H PF05837.12 OIR57372.1 - 1.1 9.6 10.2 2.5 8.5 8.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FtsL PF04999.13 OIR57372.1 - 1.6 8.7 6.8 0.2 11.6 1.1 2.1 1 1 0 2 2 2 0 Cell division protein FtsL YabA PF06156.13 OIR57372.1 - 1.8 9.2 9.1 8.3 7.1 9.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA AMP-binding PF00501.28 OIR57373.1 - 7.5e-82 275.2 0.0 9.4e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OIR57373.1 - 1.5e-19 70.7 1.5 3.1e-19 69.7 1.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OIR57373.1 - 8.9e-15 54.4 3.3 2e-14 53.2 2.0 2.3 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_C28 PF05408.11 OIR57373.1 - 0.051 13.3 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase MHC2-interact PF09307.10 OIR57373.1 - 0.16 12.0 0.0 5.5 7.0 0.0 2.3 2 0 0 2 2 2 0 CLIP, MHC2 interacting Ski_Sno PF02437.17 OIR57374.1 - 0.091 12.5 7.4 9.7 6.0 0.0 4.7 2 2 3 5 5 5 0 SKI/SNO/DAC family UPF0242 PF06785.11 OIR57375.1 - 0.056 13.5 1.9 0.097 12.8 1.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CCDC106 PF15794.5 OIR57375.1 - 0.063 13.0 2.7 0.11 12.2 2.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Drf_GBD PF06371.13 OIR57375.1 - 0.18 11.4 0.1 0.52 9.8 0.0 1.8 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Rootletin PF15035.6 OIR57375.1 - 0.35 10.9 7.9 0.3 11.1 3.4 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 OIR57375.1 - 0.39 11.0 5.1 0.79 10.0 1.7 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper KfrA_N PF11740.8 OIR57375.1 - 3.4 8.4 7.6 44 4.8 6.8 2.7 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Ribul_P_3_epim PF00834.19 OIR57378.1 - 2.7e-52 177.0 0.0 3.1e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OIR57378.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain zf-C3HC4_3 PF13920.6 OIR57379.1 - 0.00091 19.0 1.5 0.0015 18.3 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 OIR57379.1 - 0.0031 17.9 0.6 0.013 15.9 0.5 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain MAP PF03642.13 OIR57379.1 - 0.0043 17.3 0.1 13 6.2 0.1 3.6 3 0 0 3 3 3 1 MAP domain DsbG_N PF18257.1 OIR57379.1 - 0.012 15.8 0.1 5.8 7.1 0.0 3.1 3 0 0 3 3 3 0 Disulfide isomerase DsbG N-terminal Gin PF10764.9 OIR57379.1 - 0.56 10.2 1.8 1.4 8.9 1.8 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin zf-C3HC4_3 PF13920.6 OIR57380.1 - 0.00082 19.2 1.2 0.0018 18.1 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Unpaired PF15972.5 OIR57380.1 - 0.048 13.2 0.0 0.65 9.5 0.0 2.1 1 1 1 2 2 2 0 Unpaired protein zf-C3HC4_3 PF13920.6 OIR57381.1 - 0.011 15.5 5.5 0.022 14.6 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sep15_SelM PF08806.11 OIR57381.1 - 0.11 12.6 2.8 3.6 7.8 0.2 3.7 3 0 0 3 3 3 0 Sep15/SelM redox domain Gin PF10764.9 OIR57381.1 - 0.39 10.7 2.0 0.82 9.7 2.0 1.5 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Sep15_SelM PF08806.11 OIR57382.1 - 0.48 10.6 3.5 2 8.7 0.0 3.2 4 0 0 4 4 4 0 Sep15/SelM redox domain zf-C3HC4_3 PF13920.6 OIR57383.1 - 5.9e-06 26.1 7.8 1.1e-05 25.2 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR57383.1 - 0.00094 19.5 8.2 0.0021 18.4 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OIR57383.1 - 0.007 16.2 6.9 0.015 15.1 6.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 OIR57383.1 - 0.12 12.1 7.5 0.32 10.8 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 OIR57383.1 - 0.22 11.8 7.4 0.085 13.1 2.8 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger PUB PF09409.10 OIR57383.1 - 0.76 9.7 4.3 30 4.6 3.2 3.1 2 0 0 2 2 2 0 PUB domain zf-RING_5 PF14634.6 OIR57383.1 - 5.8 7.0 7.0 13 5.9 7.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain CP_ATPgrasp_1 PF04174.13 OIR57387.1 - 0.028 13.5 0.0 0.032 13.3 0.0 1.0 1 0 0 1 1 1 0 A circularly permuted ATPgrasp CP_ATPgrasp_2 PF14403.6 OIR57387.1 - 0.097 11.6 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 CBFB_NFYA PF02045.15 OIR57387.1 - 0.9 10.2 5.1 2 9.1 1.9 2.1 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Gram_pos_anchor PF00746.21 OIR57389.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif KH_2 PF07650.17 OIR57390.1 - 0.098 12.5 1.7 0.13 12.1 0.5 1.8 2 0 0 2 2 2 0 KH domain CENP-F_leu_zip PF10473.9 OIR57390.1 - 0.24 11.4 7.3 0.39 10.7 7.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_transf_90 PF05686.12 OIR57391.1 - 5.9e-32 111.0 0.1 9.3e-32 110.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 OIR57391.1 - 0.0032 17.8 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arm PF00514.23 OIR57392.1 - 1.2e-61 203.0 15.9 3.2e-10 39.7 0.3 9.9 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OIR57392.1 - 7.6e-19 67.8 5.5 0.00072 20.0 0.2 6.9 4 1 4 8 8 8 5 HEAT-like repeat IBB PF01749.20 OIR57392.1 - 1.4e-16 60.6 1.1 4.9e-16 58.9 1.1 2.0 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 OIR57392.1 - 2.6e-16 58.9 0.1 6.9e-16 57.5 0.1 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 OIR57392.1 - 1.8e-09 37.8 1.4 0.17 12.3 0.0 5.4 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.22 OIR57392.1 - 5.4e-08 32.4 4.3 0.07 13.4 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.13 OIR57392.1 - 0.0022 17.5 0.0 0.24 10.8 0.0 2.8 2 1 1 3 3 3 1 Armadillo-like RICTOR_V PF14668.6 OIR57392.1 - 0.0058 16.8 1.0 15 5.9 0.0 4.5 4 1 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, domain 5 Inhibitor_I10 PF12559.8 OIR57392.1 - 0.067 13.5 0.0 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 Serine endopeptidase inhibitors TIM PF00121.18 OIR57393.1 - 8e-82 274.3 0.1 9e-82 274.1 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase HAUS4 PF14735.6 OIR57394.1 - 1.8e-07 31.1 13.7 3e-07 30.4 13.7 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 IL5 PF02025.15 OIR57394.1 - 0.001 19.3 1.6 0.069 13.4 0.1 2.3 2 0 0 2 2 2 2 Interleukin 5 Vps54 PF07928.12 OIR57394.1 - 0.098 13.1 2.3 0.23 11.9 2.3 1.7 1 1 0 1 1 1 0 Vps54-like protein Med9 PF07544.13 OIR57394.1 - 7.4 6.7 13.3 1.9 8.6 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF5095 PF17016.5 OIR57395.1 - 5.2e-06 26.3 0.8 7e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5095) Pkinase PF00069.25 OIR57396.1 - 1.9e-55 188.1 0.0 2.8e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57396.1 - 6.7e-41 140.3 0.0 9.6e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR57396.1 - 4.5e-05 22.9 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OIR57396.1 - 0.0001 21.2 0.0 0.00025 20.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase DUF1442 PF07279.11 OIR57396.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) WD40 PF00400.32 OIR57397.1 - 3.5e-16 59.3 16.4 0.00049 20.8 0.7 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Bromodomain PF00439.25 OIR57397.1 - 4.7e-05 23.4 0.0 9.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Herpes_UL56 PF04534.12 OIR57397.1 - 0.0056 16.2 1.3 0.014 14.9 1.3 1.6 1 0 0 1 1 1 1 Herpesvirus UL56 protein Nup160 PF11715.8 OIR57397.1 - 0.097 11.3 0.0 0.54 8.8 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OIR57397.1 - 0.1 11.6 0.0 0.54 9.2 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CDC45 PF02724.14 OIR57397.1 - 0.29 9.4 5.9 0.47 8.7 5.0 1.7 2 0 0 2 2 2 0 CDC45-like protein Sec7 PF01369.20 OIR57399.1 - 1.8e-42 145.1 0.7 3.9e-42 144.0 0.7 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OIR57399.1 - 2.9e-07 30.5 5.3 4.5e-07 29.9 0.0 3.8 5 1 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF2065 PF09838.9 OIR57399.1 - 0.13 12.3 0.4 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Ribosomal_L14 PF00238.19 OIR57400.1 - 1.9e-38 131.3 0.1 2.4e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e HeH PF12949.7 OIR57401.1 - 0.34 10.7 2.0 2.8 7.7 0.1 2.6 3 0 0 3 3 3 0 HeH/LEM domain DUF5603 PF18231.1 OIR57403.1 - 0.0076 16.5 1.6 1.1 9.6 0.0 4.0 2 1 1 4 4 4 1 Domain of unknown function (DUF5603) Unpaired PF15972.5 OIR57403.1 - 0.033 13.7 1.9 0.14 11.6 0.1 2.8 2 1 2 4 4 4 0 Unpaired protein Reg_prop PF07494.11 OIR57403.1 - 0.083 13.2 4.5 59 4.4 0.0 5.1 7 0 0 7 7 7 0 Two component regulator propeller Sep15_SelM PF08806.11 OIR57404.1 - 4.9e-06 26.6 9.6 1.7 8.9 0.0 8.5 10 0 0 10 10 10 1 Sep15/SelM redox domain Reg_prop PF07494.11 OIR57404.1 - 7.6e-05 22.5 2.8 7.4 7.2 0.0 6.5 7 0 0 7 7 7 1 Two component regulator propeller Suc_Fer-like PF06999.12 OIR57404.1 - 0.071 13.0 0.0 24 4.7 0.0 4.7 3 2 0 3 3 3 0 Sucrase/ferredoxin-like Antimicrobial_1 PF08018.11 OIR57404.1 - 0.14 12.3 0.5 1.1e+02 3.1 0.0 4.1 4 0 0 4 4 4 0 Frog antimicrobial peptide GcrA PF07750.11 OIR57404.1 - 0.21 12.0 1.8 14 6.0 0.0 4.2 4 1 1 5 5 5 0 GcrA cell cycle regulator V-SNARE_C PF12352.8 OIR57405.1 - 7.6e-09 35.7 4.2 9.4e-09 35.4 4.2 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OIR57405.1 - 5.2e-05 23.1 0.9 6.6e-05 22.8 0.9 1.2 1 0 0 1 1 1 1 Sec20 DUF1043 PF06295.12 OIR57405.1 - 0.061 13.3 1.2 0.092 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2110 PF09883.9 OIR57406.1 - 0.08 12.5 0.1 22 4.5 0.0 3.4 1 1 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2110) Reg_prop PF07494.11 OIR57406.1 - 0.14 12.5 1.6 67 4.2 0.0 4.6 4 0 0 4 4 4 0 Two component regulator propeller LRR_3 PF07725.12 OIR57406.1 - 0.37 10.7 4.2 46 4.1 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat TBP PF00352.21 OIR57408.1 - 3.3e-67 222.5 0.4 2.5e-32 110.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OIR57408.1 - 9.2e-05 22.5 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OIR57408.1 - 0.36 10.7 0.1 0.36 10.7 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4295) Reprolysin_5 PF13688.6 OIR57409.1 - 2.1e-26 93.3 0.9 4.4e-26 92.3 0.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OIR57409.1 - 2.5e-25 89.5 0.5 4.9e-25 88.6 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OIR57409.1 - 2.8e-20 72.9 0.0 4.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OIR57409.1 - 2.3e-11 44.3 33.7 2.3e-11 44.3 33.7 5.3 4 2 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 OIR57409.1 - 1.1e-08 35.7 0.1 2.3e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OIR57409.1 - 2e-06 27.8 8.2 2e-06 27.8 8.2 2.4 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease PIP5K PF01504.18 OIR57410.1 - 1.2e-53 182.2 0.0 6.3e-51 173.2 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ribosomal_S13 PF00416.22 OIR57411.1 - 9.7e-45 152.1 0.3 1.1e-44 151.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF3614 PF12267.8 OIR57412.1 - 0.035 14.6 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) BAR PF03114.18 OIR57413.1 - 0.0028 17.3 1.2 0.0062 16.2 1.2 1.8 1 1 0 1 1 1 1 BAR domain DUF4477 PF14780.6 OIR57413.1 - 0.061 12.9 0.2 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) HPTransfase PF10090.9 OIR57413.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphotransferase C-terminal domain Glycos_transf_2 PF00535.26 OIR57414.1 - 6.9e-29 100.8 0.0 2.5e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OIR57414.1 - 7.8e-14 52.1 0.0 1.2e-12 48.2 0.0 2.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OIR57414.1 - 2.2e-11 43.8 0.0 2.1e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 REJ PF02010.15 OIR57414.1 - 1.7e-08 33.7 0.0 0.0013 17.6 0.0 3.0 2 1 1 3 3 3 2 REJ domain Glycos_transf_1 PF00534.20 OIR57414.1 - 2.2e-08 33.8 0.0 2.1e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 GPS PF01825.21 OIR57414.1 - 0.00083 19.8 1.7 0.00098 19.6 0.1 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TCP PF03634.13 OIR57414.1 - 0.57 10.7 4.2 1.5 9.4 4.2 1.6 1 0 0 1 1 1 0 TCP family transcription factor EGF_2 PF07974.13 OIR57414.1 - 0.84 10.1 4.7 2 8.8 4.7 1.7 1 0 0 1 1 1 0 EGF-like domain Ribosomal_L24e PF01246.20 OIR57415.1 - 2.5e-32 110.9 6.6 2.5e-32 110.9 6.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Stathmin PF00836.19 OIR57415.1 - 0.01 15.8 2.0 0.019 14.9 2.0 1.4 1 0 0 1 1 1 0 Stathmin family SsgA PF04686.12 OIR57415.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA zf-FCS PF06467.14 OIR57415.1 - 0.23 11.4 6.4 0.45 10.5 6.4 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif MRNIP PF15749.5 OIR57415.1 - 3 8.6 7.4 3.4 8.4 0.8 2.1 2 0 0 2 2 2 0 MRN-interacting protein Skp1_POZ PF03931.15 OIR57416.1 - 2e-08 34.2 0.3 0.005 17.0 0.0 2.2 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain BTB PF00651.31 OIR57416.1 - 0.00032 20.9 0.0 0.0005 20.3 0.0 1.3 1 1 0 1 1 1 1 BTB/POZ domain CENP-X PF09415.10 OIR57416.1 - 0.038 14.3 0.1 0.068 13.5 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Utp12 PF04003.12 OIR57417.1 - 0.0012 19.1 0.1 0.0023 18.2 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ribosomal_L15e PF00827.17 OIR57418.1 - 1.3e-77 259.8 6.9 1.5e-77 259.7 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Med26 PF08711.11 OIR57419.1 - 1.1e-08 34.9 0.0 1.1e-08 34.9 0.0 2.3 3 0 0 3 3 3 1 TFIIS helical bundle-like domain Ribosomal_L16 PF00252.18 OIR57420.1 - 5.8e-37 126.6 0.2 8.2e-37 126.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Cytochrom_B562 PF07361.11 OIR57422.1 - 0.0039 17.8 0.5 0.0079 16.8 0.5 1.5 1 0 0 1 1 1 1 Cytochrome b562 ERM PF00769.19 OIR57422.1 - 0.011 15.6 0.9 0.013 15.3 0.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mer2 PF09074.10 OIR57422.1 - 0.15 11.8 3.4 0.26 11.1 3.4 1.4 1 1 0 1 1 1 0 Mer2 DUF4404 PF14357.6 OIR57422.1 - 0.25 12.0 1.7 1.8 9.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) ABC_tran_CTD PF16326.5 OIR57422.1 - 0.52 10.6 3.1 0.94 9.8 3.1 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain RRM_1 PF00076.22 OIR57423.1 - 3e-17 62.2 0.1 4.2e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 OIR57423.1 - 0.034 14.1 0.1 0.072 13.1 0.1 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 OIR57423.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif GATA PF00320.27 OIR57424.1 - 8.1e-07 28.6 6.7 2.7e-06 26.9 6.7 2.0 1 0 0 1 1 1 1 GATA zinc finger ZF-HD_dimer PF04770.12 OIR57424.1 - 0.00057 20.2 1.6 0.37 11.2 0.6 2.4 2 1 0 2 2 2 2 ZF-HD protein dimerisation region Pkinase PF00069.25 OIR57426.1 - 1.2e-37 129.8 0.0 1.7e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57426.1 - 6.1e-22 78.1 0.0 8.3e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OIR57426.1 - 0.22 11.1 0.0 0.8 9.3 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Ribosomal_L10 PF00466.20 OIR57427.1 - 1.9e-12 47.2 0.9 3.7e-12 46.3 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 OIR57427.1 - 4.4e-12 45.8 0.0 7.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P 7TMR-HDED PF07697.11 OIR57427.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 1 0 1 1 1 0 7TM-HD extracellular Ribosomal_L30_N PF08079.12 OIR57427.1 - 5.9 7.2 9.0 0.34 11.2 2.4 2.1 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Epimerase PF01370.21 OIR57429.1 - 3.9e-08 33.0 0.0 9.5e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hist_deacetyl PF00850.19 OIR57430.1 - 8e-75 252.2 0.1 9.7e-75 251.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RmuC PF02646.16 OIR57432.1 - 0.13 11.3 0.1 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 RmuC family UNC119_bdg PF15435.6 OIR57433.1 - 0.038 13.5 0.2 0.044 13.3 0.2 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue COX14 PF14880.6 OIR57433.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Ribosomal_S19 PF00203.21 OIR57435.1 - 5.4e-23 80.7 0.1 7.1e-23 80.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 NARP1 PF12569.8 OIR57436.1 - 2.5e-14 53.1 4.2 2.7e-12 46.4 1.3 2.9 2 2 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 OIR57436.1 - 7.1e-13 48.9 1.5 0.0089 16.5 0.0 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR57436.1 - 1.8e-11 44.1 1.3 0.00078 19.6 0.2 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OIR57436.1 - 5.6e-11 42.3 4.5 0.00046 20.8 0.2 6.6 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OIR57436.1 - 5.3e-08 32.4 14.7 0.067 13.3 0.1 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR57436.1 - 6.3e-07 29.9 0.9 0.064 13.9 0.0 4.7 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OIR57436.1 - 9.8e-07 28.5 3.2 1.1 9.7 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR57436.1 - 1.1e-06 28.9 10.2 0.21 11.9 0.1 6.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_20 PF14561.6 OIR57436.1 - 1.2e-05 25.5 0.2 0.0022 18.3 0.0 3.5 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OIR57436.1 - 2.4e-05 23.9 4.0 0.62 10.0 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OIR57436.1 - 5.5e-05 22.5 4.2 1.1 8.5 0.2 4.6 2 2 3 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OIR57436.1 - 0.00032 20.7 1.7 0.26 11.3 0.1 3.5 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_21 PF09976.9 OIR57436.1 - 0.002 17.9 1.3 0.47 10.1 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 OIR57436.1 - 0.0029 17.9 0.0 2.4 8.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OIR57436.1 - 0.0042 16.7 1.8 2.2 8.0 0.0 4.2 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.6 OIR57436.1 - 0.02 15.5 5.2 2.4e+02 2.7 0.0 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat BTAD PF03704.17 OIR57436.1 - 0.024 15.1 3.6 3.3 8.1 1.7 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 OIR57436.1 - 0.036 14.7 0.9 4.9 8.1 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat ACP_PD PF04336.12 OIR57436.1 - 0.065 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase Fis1_TPR_C PF14853.6 OIR57436.1 - 2 8.6 4.6 4.5 7.4 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MCM PF00493.23 OIR57437.1 - 5.8e-103 342.8 0.0 9.2e-103 342.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OIR57437.1 - 4.9e-27 94.3 0.5 9.2e-27 93.4 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OIR57437.1 - 1.8e-21 76.3 0.0 4.4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OIR57437.1 - 4.4e-12 46.5 0.0 9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OIR57437.1 - 1.5e-08 34.7 0.0 3e-07 30.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OIR57437.1 - 2.5e-08 33.5 0.2 9.8e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OIR57437.1 - 0.00018 21.4 0.0 0.00043 20.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 OIR57437.1 - 0.0008 19.2 0.2 0.0023 17.7 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_18 PF13238.6 OIR57437.1 - 0.005 17.4 1.0 5.3 7.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain DUF2103 PF09876.9 OIR57437.1 - 0.1 12.6 0.9 31 4.6 0.0 3.6 3 0 0 3 3 3 0 Predicted metal-binding protein (DUF2103) Sigma54_activat PF00158.26 OIR57437.1 - 0.11 12.1 0.1 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain EGF_2 PF07974.13 OIR57438.1 - 0.039 14.3 2.0 0.039 14.3 2.0 2.1 2 0 0 2 2 2 0 EGF-like domain FtsJ PF01728.19 OIR57439.1 - 1.7e-54 184.6 0.0 3.2e-54 183.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 OIR57439.1 - 4.8e-21 75.4 31.0 4.8e-21 75.4 31.0 2.0 2 0 0 2 2 2 1 Spb1 C-terminal domain DUF3381 PF11861.8 OIR57439.1 - 4.6e-15 55.8 24.3 4.6e-15 55.8 24.3 5.0 1 1 2 3 3 3 1 Domain of unknown function (DUF3381) Sec61_beta PF03911.16 OIR57440.1 - 2.1e-08 34.1 2.6 2.4e-08 33.9 2.6 1.1 1 0 0 1 1 1 1 Sec61beta family Peptidase_S8 PF00082.22 OIR57441.1 - 5.9e-37 127.5 0.4 8.7e-37 127.0 0.4 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OIR57441.1 - 4.1e-23 81.2 2.0 3e-22 78.4 0.1 2.5 3 0 0 3 3 3 1 Proprotein convertase P-domain DM4_12 PF07841.13 OIR57442.1 - 0.1 13.2 0.1 0.76 10.5 0.0 2.4 2 0 0 2 2 2 0 DM4/DM12 family SH3BGR PF04908.15 OIR57443.1 - 3.9e-18 65.4 0.0 5.3e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 OIR57443.1 - 0.013 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin zf-RVT PF13966.6 OIR57444.1 - 0.011 16.5 0.1 0.015 16.0 0.1 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Rad60-SLD_2 PF13881.6 OIR57445.1 - 3e-10 40.2 0.1 3.3e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OIR57445.1 - 0.0014 19.1 0.0 0.002 18.7 0.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Prefoldin_2 PF01920.20 OIR57446.1 - 4.7e-08 32.9 0.1 5.3e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4795 PF16043.5 OIR57446.1 - 0.0018 17.9 0.4 0.0021 17.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF3597 PF12200.8 OIR57447.1 - 0.08 13.5 0.0 0.093 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) zf-RVT PF13966.6 OIR57448.1 - 0.079 13.7 2.5 0.16 12.7 1.1 2.3 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase DUF3700 PF12481.8 OIR57450.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein Ribosomal_L2_C PF03947.18 OIR57452.1 - 4.1e-46 156.3 2.3 6.4e-46 155.6 2.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OIR57452.1 - 9.1e-08 32.0 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain zf-RING_2 PF13639.6 OIR57453.1 - 2.3e-10 40.7 8.0 2.3e-10 40.7 8.0 2.4 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 OIR57453.1 - 9.8e-08 32.2 10.8 1.4e-07 31.6 8.8 2.2 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OIR57453.1 - 1.7e-07 31.0 7.5 1.7e-07 31.0 7.5 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR57453.1 - 2.8e-07 30.3 6.8 2.8e-07 30.3 6.8 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR57453.1 - 1e-06 28.5 4.5 1e-06 28.5 4.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OIR57453.1 - 1.6e-06 28.0 4.0 5.8e-06 26.2 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OIR57453.1 - 8.7e-06 25.4 4.1 8.7e-06 25.4 4.1 2.5 3 0 0 3 3 2 1 RING-like zinc finger TPR_MLP1_2 PF07926.12 OIR57453.1 - 0.00046 20.2 1.5 0.00084 19.4 1.5 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Prok-RING_4 PF14447.6 OIR57453.1 - 0.0018 18.1 4.3 0.0018 18.1 4.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OIR57453.1 - 0.0019 18.1 6.4 0.0019 18.1 6.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Spc7 PF08317.11 OIR57453.1 - 0.0022 16.9 2.7 0.0036 16.2 2.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Zn_ribbon_17 PF17120.5 OIR57453.1 - 0.0026 17.4 4.3 0.0065 16.1 3.2 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 OIR57453.1 - 0.0056 16.7 4.1 0.017 15.2 4.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TolA_bind_tri PF16331.5 OIR57453.1 - 0.008 16.2 2.1 0.015 15.3 2.1 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation Mst1_SARAH PF11629.8 OIR57453.1 - 0.023 14.8 1.8 0.053 13.6 1.6 1.7 1 1 0 1 1 1 0 C terminal SARAH domain of Mst1 Med9 PF07544.13 OIR57453.1 - 0.054 13.6 0.6 0.11 12.6 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AbrB PF05145.12 OIR57453.1 - 0.1 11.5 1.3 0.17 10.8 1.3 1.4 1 0 0 1 1 1 0 Transition state regulatory protein AbrB CENP-F_leu_zip PF10473.9 OIR57453.1 - 0.14 12.2 4.7 0.23 11.4 4.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 OIR57453.1 - 0.27 11.3 3.4 5 7.3 0.6 2.3 1 1 1 2 2 2 0 bZIP transcription factor Synaptobrevin PF00957.21 OIR57453.1 - 0.32 10.8 1.7 1.1 9.1 0.5 2.3 1 1 1 2 2 2 0 Synaptobrevin Vps39_2 PF10367.9 OIR57453.1 - 0.37 11.3 2.1 19 5.8 0.3 2.8 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 ZapB PF06005.12 OIR57453.1 - 0.42 11.1 3.4 0.94 10.0 3.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF1664 PF07889.12 OIR57453.1 - 0.45 10.6 1.5 5.9 7.0 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING-like PF08746.11 OIR57453.1 - 1.4 9.3 8.4 7.1 7.0 4.6 2.8 2 0 0 2 2 2 0 RING-like domain Pox_A_type_inc PF04508.12 OIR57453.1 - 1.5 8.8 9.6 1.1 9.2 1.6 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4400 PF14348.6 OIR57453.1 - 1.5 8.2 5.4 1.7 8.1 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Tsc35 PF15079.6 OIR57453.1 - 1.6 8.2 4.2 2.8 7.5 4.2 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 RINGv PF12906.7 OIR57453.1 - 1.7 8.9 9.1 10 6.3 6.7 2.6 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 OIR57453.1 - 9 6.6 14.5 0.046 13.9 5.5 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Ribosomal_L22e PF01776.17 OIR57454.1 - 3.2e-27 95.1 0.1 2.5e-12 47.1 0.1 2.0 2 0 0 2 2 2 2 Ribosomal L22e protein family Apolipoprotein PF01442.18 OIR57455.1 - 0.012 15.5 2.7 0.021 14.7 1.1 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Y_phosphatase3 PF13350.6 OIR57455.1 - 0.022 14.7 1.1 0.043 13.8 0.3 1.7 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF2281 PF10047.9 OIR57455.1 - 0.054 14.2 1.5 0.74 10.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2281) Fib_alpha PF08702.10 OIR57455.1 - 0.065 13.4 0.9 0.31 11.2 0.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IFN-gamma PF00714.17 OIR57455.1 - 0.18 11.6 3.1 1.4 8.8 3.1 2.0 1 1 0 1 1 1 0 Interferon gamma Eaf7 PF07904.13 OIR57455.1 - 0.21 12.0 6.2 1.8 9.0 3.7 2.3 1 1 1 2 2 2 0 Chromatin modification-related protein EAF7 TetR_C_15 PF17918.1 OIR57456.1 - 0.0082 16.9 0.1 0.0094 16.7 0.1 1.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Histone PF00125.24 OIR57456.1 - 0.074 13.4 0.2 15 6.0 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 HK97-gp10_like PF04883.12 OIR57456.1 - 0.1 13.6 0.0 0.25 12.3 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component TAF6_C PF07571.13 OIR57457.1 - 1.2e-27 96.1 0.0 2.4e-27 95.1 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 OIR57457.1 - 7.1e-24 83.8 0.1 3.2e-23 81.7 0.0 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 OIR57457.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OIR57457.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 HEAT PF02985.22 OIR57457.1 - 0.56 10.6 5.6 4 8.0 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat Gpi16 PF04113.14 OIR57458.1 - 0.0022 16.6 0.1 0.0056 15.2 0.1 1.7 1 1 1 2 2 2 1 Gpi16 subunit, GPI transamidase component HD_assoc PF13286.6 OIR57458.1 - 0.08 13.5 0.2 0.51 10.9 0.1 2.1 1 1 1 2 2 2 0 Phosphohydrolase-associated domain Met_10 PF02475.16 OIR57459.1 - 1.5e-60 204.3 0.0 2e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 OIR57459.1 - 7.7e-05 22.2 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OIR57459.1 - 0.00056 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 OIR57459.1 - 0.0015 18.5 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OIR57459.1 - 0.0015 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 OIR57459.1 - 0.0016 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OIR57459.1 - 0.002 18.8 0.0 0.0046 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.15 OIR57459.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.14 OIR57459.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 OIR57459.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 OIR57459.1 - 0.023 15.3 0.0 0.06 14.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.11 OIR57459.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) tRNA_U5-meth_tr PF05958.11 OIR57459.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Ribosomal_L30 PF00327.20 OIR57459.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e ATP-synt_ab PF00006.25 OIR57460.1 - 2.1e-103 344.5 0.0 4.7e-103 343.4 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OIR57460.1 - 3.5e-41 139.9 0.0 7.1e-41 138.9 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OIR57460.1 - 7.2e-09 36.1 4.2 1.8e-08 34.8 4.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.6 OIR57460.1 - 0.17 11.9 0.0 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-patch PF01585.23 OIR57461.1 - 1.6e-11 43.9 0.9 3.8e-11 42.7 0.9 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OIR57461.1 - 3.3e-06 27.1 1.7 7.3e-06 26.0 1.2 1.9 1 1 0 1 1 1 1 G-patch domain Ribosomal_L27e PF01777.18 OIR57462.1 - 4.3e-20 71.8 2.3 6.4e-20 71.3 2.3 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family Pkinase PF00069.25 OIR57463.1 - 2.6e-41 141.7 0.0 3.2e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57463.1 - 2.2e-17 63.2 0.0 2.9e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OIR57463.1 - 2.1e-09 37.3 0.0 3.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OIR57463.1 - 6.8e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OIR57463.1 - 0.00013 21.4 0.0 0.00032 20.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OIR57463.1 - 0.00018 20.4 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OIR57463.1 - 0.00034 20.6 0.0 0.0042 17.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OIR57463.1 - 0.00098 18.8 0.0 0.011 15.3 0.0 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 OIR57463.1 - 0.048 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Baculo_LEF5_C PF11792.8 OIR57464.1 - 0.009 15.7 0.1 0.51 10.1 0.0 2.9 3 0 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain TFIIE_alpha PF02002.17 OIR57464.1 - 0.018 14.9 0.0 0.058 13.3 0.0 1.9 1 0 0 1 1 1 0 TFIIE alpha subunit Gag_p24 PF00607.20 OIR57465.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) DUF4952 PF16310.5 OIR57466.1 - 0.038 14.2 0.0 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Domian of unknown function (DUF4952) COMP PF11598.8 OIR57466.1 - 2.7 8.6 4.9 82 3.8 2.8 2.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Mu-like_Pro PF10123.9 OIR57466.1 - 3.9 6.9 9.0 6.8 6.1 9.0 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein ATP-synt_E_2 PF08112.11 OIR57466.1 - 4.1 7.8 10.4 0.24 11.7 3.2 2.6 2 0 0 2 2 2 0 ATP synthase epsilon subunit DUF563 PF04577.14 OIR57467.1 - 2.4e-13 50.7 0.0 4.8e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Pex14_N PF04695.13 OIR57467.1 - 0.23 12.1 3.1 0.48 11.1 3.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 OIR57468.1 - 2.7e-21 75.4 20.2 0.0029 18.4 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57468.1 - 1.3e-07 31.8 4.2 0.1 12.9 0.2 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OIR57468.1 - 3.6e-05 22.9 1.0 0.089 11.7 0.0 3.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Sen15 PF09631.10 OIR57468.1 - 0.027 14.8 0.1 1.3 9.4 0.0 2.9 2 1 1 3 3 3 0 Sen15 protein Diphthamide_syn PF01866.17 OIR57469.1 - 3.4e-14 53.0 0.0 1.9e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein WD40 PF00400.32 OIR57470.1 - 1.5e-14 54.1 2.0 2.4e-05 25.0 0.1 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57470.1 - 3.8e-08 33.5 0.1 0.055 13.8 0.0 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UTP15_C PF09384.10 OIR57470.1 - 4e-07 29.8 0.1 6e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal Thioredoxin PF00085.20 OIR57471.1 - 7.1e-26 90.2 0.0 8.9e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 OIR57471.1 - 0.00035 20.5 0.2 0.00072 19.5 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 OIR57471.1 - 0.00041 20.8 0.3 0.0051 17.3 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 OIR57471.1 - 0.00084 18.8 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OIR57471.1 - 0.0013 19.1 0.0 0.047 14.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.6 OIR57471.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.10 OIR57471.1 - 0.032 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 OIR57471.1 - 0.049 13.7 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Ig_J_chain PF15097.6 OIR57471.1 - 0.084 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Immunoglobulin J chain Lar_restr_allev PF14354.6 OIR57471.1 - 0.15 12.5 1.5 0.22 11.9 1.5 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar Thioredoxin_7 PF13899.6 OIR57471.1 - 0.18 12.0 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DNA_primase_S PF01896.19 OIR57472.1 - 1.9e-50 171.4 0.1 2.8e-50 170.8 0.1 1.3 1 0 0 1 1 1 1 DNA primase small subunit Ada3 PF10198.9 OIR57473.1 - 5.6e-08 33.0 7.0 5.6e-08 33.0 7.0 2.0 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 Nop10p PF04135.12 OIR57474.1 - 9.3e-21 73.6 0.9 1e-20 73.5 0.9 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family AP_endonuc_2 PF01261.24 OIR57476.1 - 2.7e-31 108.7 0.0 3.8e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ORC2 PF04084.14 OIR57477.1 - 7.8e-23 80.9 8.6 1.6e-10 40.5 5.0 3.0 1 1 1 2 2 2 2 Origin recognition complex subunit 2 zf-C3HC4_3 PF13920.6 OIR57478.1 - 0.00083 19.2 4.3 0.0019 18.0 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4385 PF14328.6 OIR57478.1 - 0.0081 16.2 0.8 13 5.9 0.0 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF4385) Reg_prop PF07494.11 OIR57478.1 - 0.0084 16.2 9.9 1.7e+02 3.0 0.0 8.6 10 0 0 10 10 10 0 Two component regulator propeller zinc_ribbon_12 PF11331.8 OIR57478.1 - 0.011 15.5 0.9 0.011 15.5 0.9 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-UDP PF14569.6 OIR57478.1 - 0.14 12.3 2.4 0.33 11.1 2.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Nucleic_acid_bd PF13820.6 OIR57478.1 - 0.17 11.7 5.1 57 3.5 0.0 6.1 8 0 0 8 8 8 0 Putative nucleic acid-binding region ANAPC15 PF15243.6 OIR57478.1 - 0.26 11.7 29.6 9.4 6.7 0.0 9.1 10 1 1 11 11 11 0 Anaphase-promoting complex subunit 15 Nuc_sug_transp PF04142.15 OIR57478.1 - 0.74 8.9 5.5 33 3.5 0.0 5.0 5 0 0 5 5 5 0 Nucleotide-sugar transporter DUF3982 PF13138.6 OIR57478.1 - 2 8.3 5.9 11 6.0 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3982) MlaD PF02470.20 OIR57480.1 - 0.0011 19.2 0.0 5.7 7.3 0.0 3.0 1 1 2 3 3 3 2 MlaD protein GcrA PF07750.11 OIR57480.1 - 0.0015 19.0 0.1 1.4 9.4 0.0 2.5 1 1 1 3 3 3 2 GcrA cell cycle regulator Nucleic_acid_bd PF13820.6 OIR57480.1 - 0.1 12.4 1.7 8.3 6.3 0.0 2.6 3 0 0 3 3 3 0 Putative nucleic acid-binding region Intein_splicing PF14890.6 OIR57480.1 - 0.37 10.7 1.4 3.4 7.6 0.4 2.2 1 1 1 2 2 2 0 Intein splicing domain MlaD PF02470.20 OIR57481.1 - 0.0011 19.3 0.0 1.6 9.0 0.0 2.9 3 0 0 3 3 3 2 MlaD protein Nucleic_acid_bd PF13820.6 OIR57481.1 - 0.063 13.1 0.1 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative nucleic acid-binding region Sep15_SelM PF08806.11 OIR57481.1 - 0.067 13.4 0.1 17 5.7 0.1 2.8 3 0 0 3 3 3 0 Sep15/SelM redox domain TTRAP PF14203.6 OIR57482.1 - 0.0012 18.8 3.1 10 6.2 0.0 5.1 5 0 0 5 5 5 1 Putative tranposon-transfer assisting protein QSOX_Trx1 PF18108.1 OIR57482.1 - 0.0013 18.9 9.2 0.15 12.3 0.4 4.6 3 2 2 5 5 5 2 QSOX Trx-like domain BAF250_C PF12031.8 OIR57482.1 - 0.0032 16.8 1.2 0.35 10.1 0.1 3.3 3 0 0 3 3 3 1 SWI/SNF-like complex subunit BAF250/Osa DUF2714 PF10896.8 OIR57482.1 - 0.03 14.4 4.3 0.63 10.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2714) DUF4270 PF14092.6 OIR57482.1 - 0.11 11.6 0.0 10 5.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4270) DUF3253 PF11625.8 OIR57483.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) RVT_1 PF00078.27 OIR57486.1 - 9.8e-41 139.7 0.0 1.5e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OIR57486.1 - 0.07 13.0 0.0 0.32 10.9 0.0 2.2 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase DUF1582 PF07621.11 OIR57487.1 - 0.015 15.2 0.3 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) UPF0242 PF06785.11 OIR57487.1 - 0.067 13.3 1.7 0.12 12.4 1.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4728 PF15860.5 OIR57488.1 - 0.055 14.1 1.7 0.067 13.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4728) MMR_HSR1_Xtn PF16897.5 OIR57489.1 - 6.2e-39 132.3 0.0 1.2e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OIR57489.1 - 1.5e-20 73.0 0.0 2.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OIR57489.1 - 6.9e-19 68.0 0.0 1.4e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OIR57489.1 - 1.1e-09 38.0 0.1 2.9e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OIR57489.1 - 0.0025 17.4 0.2 2.6 7.5 0.0 3.5 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 OIR57489.1 - 0.0082 15.2 0.6 0.017 14.1 0.2 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OIR57489.1 - 0.14 12.2 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_pol_Rpb2_6 PF00562.28 OIR57490.1 - 2.6e-107 359.3 0.0 4.6e-107 358.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OIR57490.1 - 1.5e-40 138.9 0.0 2.5e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 OIR57490.1 - 1.7e-28 98.8 0.2 4.1e-28 97.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 OIR57490.1 - 8.6e-19 67.6 0.1 3.1e-18 65.8 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OIR57490.1 - 6.2e-18 64.7 0.1 2.5e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 OIR57490.1 - 3.3e-16 59.5 0.0 6.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 OIR57490.1 - 1.6e-06 28.6 0.0 4.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RasGAP PF00616.19 OIR57493.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF1325 PF07039.11 OIR57493.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 SGF29 tudor-like domain Glycos_transf_4 PF00953.21 OIR57494.1 - 4.8e-30 104.7 1.2 1.2e-29 103.4 1.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 4 DUF2637 PF10935.8 OIR57494.1 - 0.04 13.8 1.2 0.52 10.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) FIN1 PF17300.2 OIR57494.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 RNase_PH PF01138.21 OIR57495.1 - 1.9e-08 34.8 0.3 4.8e-08 33.6 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OIR57495.1 - 0.003 17.6 0.0 0.0076 16.3 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 UPF0160 PF03690.13 OIR57496.1 - 4.2e-102 342.0 1.6 4.8e-102 341.9 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) YjeJ PF15922.5 OIR57496.1 - 0.16 11.1 0.5 0.24 10.6 0.5 1.2 1 0 0 1 1 1 0 YjeJ-like SAP PF02037.27 OIR57497.1 - 2.7e-06 27.0 2.2 3.3e-06 26.7 0.8 1.8 2 0 0 2 2 2 1 SAP domain RtcB PF01139.17 OIR57498.1 - 4.6e-139 464.2 2.2 5.3e-139 463.9 2.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Syja_N PF02383.18 OIR57499.1 - 5.6e-64 216.5 0.3 7.8e-64 216.0 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain TFIID_20kDa PF03847.13 OIR57501.1 - 0.0012 19.3 0.1 0.0019 18.7 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RasGEF PF00617.19 OIR57502.1 - 1.7e-17 64.2 0.0 2.7e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Pescadillo_N PF06732.11 OIR57504.1 - 1.4e-50 172.4 1.0 2.3e-50 171.6 1.0 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 OIR57504.1 - 0.0012 19.2 0.0 0.0057 17.1 0.0 2.2 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Ribosomal_L14e PF01929.17 OIR57505.1 - 1.2e-12 48.1 0.5 1.7e-12 47.7 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 Blo-t-5 PF11642.8 OIR57505.1 - 0.015 15.2 1.5 0.04 13.9 1.4 1.9 1 1 1 2 2 2 0 Mite allergen Blo t 5 Utp13 PF08625.11 OIR57506.1 - 7.2e-11 42.2 0.3 1.1e-10 41.6 0.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Adap_comp_sub PF00928.21 OIR57507.1 - 1.7e-08 34.2 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF2322 PF10084.9 OIR57507.1 - 0.0075 16.3 0.0 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2322) ArfGap PF01412.18 OIR57508.1 - 1.6e-29 102.4 0.3 1.6e-29 102.4 0.3 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf HSP20 PF00011.21 OIR57509.1 - 1.2e-17 63.9 1.7 1.4e-17 63.7 1.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OIR57509.1 - 1.5e-08 34.1 0.2 2.6e-08 33.3 0.2 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA GvpH PF05455.11 OIR57509.1 - 0.0026 17.9 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 GvpH FKBP26_C PF18046.1 OIR57509.1 - 0.09 12.9 1.1 2 8.5 0.5 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal CS PF04969.16 OIR57509.1 - 0.12 13.4 2.4 0.23 12.5 2.4 1.5 1 1 0 1 1 1 0 CS domain SNF2_N PF00176.23 OIR57510.1 - 1.7e-59 201.3 0.1 3.3e-59 200.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OIR57510.1 - 2.8e-18 66.3 0.0 6.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OIR57510.1 - 1.6e-12 47.1 0.1 1.8e-06 27.7 0.2 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OIR57510.1 - 4.2e-08 33.4 0.0 9.7e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OIR57510.1 - 6.5e-08 32.1 0.1 2e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OIR57510.1 - 0.00029 20.1 0.1 0.00072 18.8 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase RTP PF02334.16 OIR57510.1 - 0.22 12.2 2.4 3 8.5 0.1 3.3 3 0 0 3 3 3 0 Replication terminator protein Bromodomain PF00439.25 OIR57511.1 - 1.1e-39 134.4 0.0 3.6e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 OIR57511.1 - 1e-13 51.2 3.1 1e-13 51.2 3.1 1.9 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation ECM11 PF15463.6 OIR57511.1 - 0.0041 17.7 0.6 0.019 15.5 0.1 2.2 2 0 0 2 2 2 1 Extracellular mutant protein 11 DUF4290 PF14123.6 OIR57511.1 - 0.14 11.7 0.8 0.42 10.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4290) DUF3357 PF11837.8 OIR57512.1 - 0.011 16.1 0.2 0.45 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) GPR15L PF15854.5 OIR57512.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.2 2 1 1 3 3 3 0 G-protein coupled receptor ligand 15 DUF4834 PF16118.5 OIR57512.1 - 0.34 11.9 0.2 0.34 11.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF5098 PF17023.5 OIR57513.1 - 6e-06 25.5 6.5 1.4e-05 24.3 6.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5098) AsnA PF03590.15 OIR57514.1 - 1.8e-88 296.1 0.0 2.2e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 OIR57514.1 - 0.00081 18.6 1.9 0.0044 16.1 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Inv-AAD PF18785.1 OIR57514.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase AAA PF00004.29 OIR57516.1 - 3.5e-44 150.4 0.1 8e-44 149.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OIR57516.1 - 1.3e-13 50.6 1.3 3.8e-13 49.2 0.2 2.4 3 0 0 3 3 3 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OIR57516.1 - 2.8e-10 39.8 0.0 6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OIR57516.1 - 9.7e-07 29.3 0.3 6.2e-05 23.4 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OIR57516.1 - 1.2e-06 28.6 0.2 5.9e-06 26.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OIR57516.1 - 3.6e-06 27.2 0.0 8.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OIR57516.1 - 4e-05 22.9 0.0 7.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OIR57516.1 - 0.00011 22.5 0.7 0.0094 16.2 0.1 2.5 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 OIR57516.1 - 0.00023 21.1 0.7 0.0045 16.9 0.0 2.7 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 OIR57516.1 - 0.00047 20.5 0.0 0.0025 18.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 OIR57516.1 - 0.00053 19.3 0.1 0.002 17.4 0.0 1.9 1 1 1 2 2 2 1 TIP49 P-loop domain TsaE PF02367.17 OIR57516.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 OIR57516.1 - 0.0014 18.4 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 OIR57516.1 - 0.0029 17.1 0.1 0.016 14.8 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 OIR57516.1 - 0.0069 15.8 0.5 0.12 11.7 0.0 2.3 1 1 1 2 2 2 1 KaiC AAA_28 PF13521.6 OIR57516.1 - 0.0084 16.4 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OIR57516.1 - 0.0091 15.7 0.1 0.067 12.9 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 OIR57516.1 - 0.011 15.5 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OIR57516.1 - 0.013 15.2 0.1 0.031 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OIR57516.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OIR57516.1 - 0.016 15.1 0.1 0.045 13.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 OIR57516.1 - 0.02 14.3 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 OIR57516.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OIR57516.1 - 0.031 14.8 0.0 0.058 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OIR57516.1 - 0.034 13.9 0.2 0.099 12.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 OIR57516.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Mg_chelatase PF01078.21 OIR57516.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OIR57516.1 - 0.059 13.1 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 OIR57516.1 - 0.081 13.4 0.0 0.28 11.7 0.0 2.2 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OIR57516.1 - 0.15 11.7 0.6 0.72 9.4 0.1 2.0 1 1 0 2 2 2 0 AAA domain DPM2 PF07297.12 OIR57518.1 - 0.00034 20.8 4.4 0.0004 20.6 4.4 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Colicin_V PF02674.16 OIR57518.1 - 0.035 14.1 3.2 0.041 13.8 3.2 1.1 1 0 0 1 1 1 0 Colicin V production protein DUF2207 PF09972.9 OIR57518.1 - 0.58 8.8 2.1 0.62 8.8 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TssO PF17561.2 OIR57518.1 - 4.4 7.4 4.3 13 5.9 1.3 2.0 2 0 0 2 2 2 0 Type VI secretion system, TssO IQ_SEC7_PH PF16453.5 OIR57521.1 - 0.17 11.9 0.7 0.26 11.3 0.7 1.3 1 0 0 1 1 1 0 PH domain SecA_DEAD PF07517.14 OIR57522.1 - 6.3e-27 94.6 0.0 6.3e-27 94.6 0.0 3.7 4 0 0 4 4 4 1 SecA DEAD-like domain DUF3638 PF12340.8 OIR57522.1 - 2.8e-05 23.6 0.0 8.4e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) SecA_PP_bind PF01043.20 OIR57522.1 - 0.0013 19.3 0.0 0.0013 19.3 0.0 4.1 4 0 0 4 4 4 1 SecA preprotein cross-linking domain Helicase_C PF00271.31 OIR57522.1 - 0.047 14.0 3.1 0.065 13.6 0.1 3.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain DUF3006 PF11213.8 OIR57522.1 - 0.24 11.6 3.9 4.1 7.7 3.9 3.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) DUF4225 PF13988.6 OIR57522.1 - 5.7 6.5 6.0 0.68 9.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) V-ATPase_G PF03179.15 OIR57524.1 - 8.4e-22 77.7 21.2 9.8e-22 77.5 21.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 OIR57524.1 - 0.00011 22.5 20.1 0.00012 22.4 20.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF883 PF05957.13 OIR57524.1 - 0.0094 16.5 14.1 0.048 14.3 6.0 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Phasin PF05597.11 OIR57524.1 - 0.032 14.2 12.6 0.12 12.4 12.8 1.7 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BAR_3 PF16746.5 OIR57524.1 - 0.032 13.9 11.2 0.039 13.6 11.2 1.0 1 0 0 1 1 1 0 BAR domain of APPL family OmpH PF03938.14 OIR57524.1 - 0.064 13.6 16.5 0.085 13.2 16.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DinB_2 PF12867.7 OIR57524.1 - 0.069 13.7 0.3 0.37 11.3 0.3 1.8 1 1 0 1 1 1 0 DinB superfamily Apolipoprotein PF01442.18 OIR57524.1 - 0.072 13.0 15.7 0.28 11.0 4.7 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Focal_AT PF03623.13 OIR57524.1 - 0.075 13.0 4.6 0.098 12.6 4.6 1.3 1 1 0 1 1 1 0 Focal adhesion targeting region FdhE PF04216.12 OIR57524.1 - 0.14 12.0 5.6 0.16 11.9 5.6 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF4600 PF15372.6 OIR57524.1 - 0.17 12.3 14.3 0.45 10.9 2.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4600) Vfa1 PF08432.10 OIR57524.1 - 0.19 12.0 12.1 0.25 11.7 12.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ATP-synt_B PF00430.18 OIR57524.1 - 0.26 11.4 24.8 0.48 10.5 21.2 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4709 PF15821.5 OIR57524.1 - 0.26 11.6 7.1 0.31 11.3 6.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) YtxH PF12732.7 OIR57524.1 - 0.37 11.3 11.6 0.82 10.3 2.9 2.1 2 0 0 2 2 2 0 YtxH-like protein Atg14 PF10186.9 OIR57524.1 - 0.47 9.5 19.0 0.52 9.3 19.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNase_J_C PF17770.1 OIR57524.1 - 0.54 11.3 11.4 0.15 13.1 2.6 2.2 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain LCIB_C_CA PF18599.1 OIR57524.1 - 0.55 9.5 3.9 0.64 9.3 3.9 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Carbpep_Y_N PF05388.11 OIR57524.1 - 0.92 10.1 4.3 5.5 7.5 0.3 2.0 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide tRNA-synt_1b PF00579.25 OIR57524.1 - 0.98 8.7 5.5 1.2 8.4 5.5 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) YbjQ_1 PF01906.17 OIR57524.1 - 1.2 9.8 4.3 6.8 7.4 0.3 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding TMPIT PF07851.13 OIR57524.1 - 1.3 8.2 10.2 1.5 8.0 10.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein SIR4_SID PF16991.5 OIR57524.1 - 1.5 8.8 9.0 1.7 8.7 9.0 1.1 1 0 0 1 1 1 0 Sir4 SID domain DUF1664 PF07889.12 OIR57524.1 - 1.8 8.6 7.5 11 6.1 7.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Mitofilin PF09731.9 OIR57524.1 - 1.9 7.2 19.7 2.1 7.1 19.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApoO PF09769.9 OIR57524.1 - 2.3 8.2 4.7 3.7 7.5 0.5 2.1 1 1 1 2 2 2 0 Apolipoprotein O DUF4407 PF14362.6 OIR57524.1 - 2.4 7.5 11.1 3.5 6.9 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ead_Ea22 PF13935.6 OIR57524.1 - 2.6 8.7 14.4 4.7 7.9 14.4 1.5 1 1 0 1 1 1 0 Ead/Ea22-like protein Exonuc_VII_L PF02601.15 OIR57524.1 - 3.1 7.3 10.4 3.5 7.1 10.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit OrfB_IS605 PF01385.19 OIR57524.1 - 3.7 7.8 10.3 28 5.0 10.3 2.0 1 1 0 1 1 1 0 Probable transposase ALMT PF11744.8 OIR57524.1 - 5 5.8 9.9 5.4 5.7 9.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1690 PF07956.11 OIR57524.1 - 9.1 6.7 16.6 2.4 8.6 8.8 1.9 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) CemA PF03040.14 OIR57524.1 - 9.2 6.1 8.2 12 5.7 8.2 1.3 1 0 0 1 1 1 0 CemA family TRAPP PF04051.16 OIR57525.1 - 1.9e-24 86.1 0.0 2.2e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SLAM PF06214.11 OIR57525.1 - 0.024 14.6 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein SKA1 PF07160.12 OIR57526.1 - 6.3e-32 111.3 8.0 2.7e-31 109.3 8.0 1.8 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4404 PF14357.6 OIR57526.1 - 0.046 14.4 4.8 0.18 12.5 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Ca_bind_SSO6904 PF18249.1 OIR57526.1 - 0.055 13.8 1.1 0.34 11.3 0.1 2.3 2 0 0 2 2 2 0 Calcium binding protein SSO6904 VSG_B PF13206.6 OIR57526.1 - 0.067 12.4 3.3 0.13 11.5 3.3 1.4 1 1 0 1 1 1 0 Trypanosomal VSG domain MCRS_N PF13325.6 OIR57527.1 - 0.0073 16.3 0.3 0.0079 16.2 0.3 1.1 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Oxysterol_BP PF01237.18 OIR57528.1 - 8.2e-73 245.4 0.1 1.2e-72 244.8 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Sun2_CC2 PF18580.1 OIR57528.1 - 0.043 14.1 0.4 0.12 12.6 0.4 1.8 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 TPR_2 PF07719.17 OIR57530.1 - 1.3e-17 62.4 6.0 0.071 13.3 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 OIR57530.1 - 4.2e-16 58.0 5.6 0.051 13.4 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 OIR57530.1 - 1.4e-11 43.9 0.0 0.24 11.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 OIR57530.1 - 6e-11 42.2 1.8 0.19 12.6 0.0 6.9 3 2 6 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 OIR57530.1 - 1.3e-10 41.8 1.6 0.0026 18.4 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OIR57530.1 - 1.7e-10 40.1 1.3 0.075 13.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OIR57530.1 - 7.4e-10 38.3 4.3 2.1 8.8 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR57530.1 - 6.4e-08 32.8 3.6 0.035 14.4 0.0 5.6 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 OIR57530.1 - 7.5e-07 28.7 4.1 0.00041 20.0 0.0 4.3 5 1 1 6 6 6 2 TPR repeat TPR_19 PF14559.6 OIR57530.1 - 1.3e-06 28.8 0.0 0.32 11.5 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 OIR57530.1 - 0.0012 18.6 0.1 0.0072 16.1 0.0 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 OIR57530.1 - 0.0024 18.4 4.5 30 5.5 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR57530.1 - 0.055 13.7 0.5 13 6.1 0.0 3.2 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OIR57530.1 - 0.099 11.8 0.0 10 5.2 0.0 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 OIR57530.1 - 0.29 11.5 1.5 6.8 7.2 0.0 3.6 4 0 0 4 4 3 0 PPR repeat Beta-Casp PF10996.8 OIR57531.1 - 8.4e-19 67.9 0.0 1.5e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OIR57531.1 - 4.5e-12 45.8 0.2 7.8e-11 41.8 0.2 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OIR57531.1 - 4.5e-11 42.5 0.0 9.3e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 OIR57531.1 - 2.4e-09 37.5 0.6 8.5e-08 32.4 0.6 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OIR57531.1 - 5.6e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OIR57531.1 - 0.00048 20.1 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF3991 PF13154.6 OIR57531.1 - 0.17 12.2 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) Got1 PF04178.12 OIR57532.1 - 1.1e-18 67.8 17.2 1.4e-18 67.4 17.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Methyltransf_16 PF10294.9 OIR57533.1 - 4.6e-11 42.8 0.0 6.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 OIR57533.1 - 0.012 16.3 0.2 0.023 15.4 0.2 1.5 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OIR57533.1 - 0.021 14.2 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltrans_SAM PF10672.9 OIR57533.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Lectin_C PF00059.21 OIR57534.1 - 1.8e-05 25.4 0.2 3.4e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Lectin C-type domain DUF4906 PF16249.5 OIR57534.1 - 0.035 13.9 0.6 0.052 13.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) Prefoldin_2 PF01920.20 OIR57535.1 - 1.9e-08 34.2 1.5 2.2e-08 34.0 1.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sugarporin_N PF11471.8 OIR57535.1 - 0.0052 16.7 0.9 0.0052 16.7 0.9 1.8 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension Prefoldin PF02996.17 OIR57535.1 - 0.056 13.4 4.5 0.18 11.7 2.6 1.9 1 1 1 2 2 2 0 Prefoldin subunit DnaJ PF00226.31 OIR57536.1 - 8.6e-19 67.4 0.4 2.1e-18 66.2 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 OIR57536.1 - 7.3e-13 48.3 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF620 PF04788.12 OIR57536.1 - 0.063 12.7 0.1 5.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF620) ASL_C PF08328.11 OIR57536.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal DsbG_N PF18257.1 OIR57537.1 - 0.0076 16.4 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Disulfide isomerase DsbG N-terminal Spt20 PF12090.8 OIR57538.1 - 1.3e-08 34.8 0.4 0.00029 20.5 0.1 2.2 1 1 1 2 2 2 2 Spt20 family DEAD PF00270.29 OIR57539.1 - 5.8e-43 146.7 1.3 9.7e-43 146.0 1.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR57539.1 - 5.5e-31 107.2 0.5 2.4e-30 105.1 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR57539.1 - 9e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OIR57539.1 - 9.9e-05 22.1 0.5 0.00021 21.1 0.5 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OIR57539.1 - 0.005 17.1 0.4 0.021 15.1 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OIR57539.1 - 0.0069 16.8 0.3 0.025 15.0 0.3 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OIR57539.1 - 0.0082 16.5 1.2 0.015 15.6 0.7 1.8 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 OIR57539.1 - 0.012 15.4 0.1 0.028 14.3 0.1 1.6 1 1 0 1 1 1 0 Helicase CMS1 PF14617.6 OIR57539.1 - 0.037 13.3 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF5615 PF18480.1 OIR57539.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) UvrD-helicase PF00580.21 OIR57539.1 - 0.086 12.3 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain FYVE PF01363.21 OIR57540.1 - 2.7e-16 59.5 12.9 2.7e-16 59.5 12.9 2.4 2 0 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.6 OIR57540.1 - 1.2e-06 28.7 4.8 1.2e-06 28.7 4.8 4.2 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OIR57540.1 - 0.012 15.3 6.5 0.045 13.5 6.5 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 OIR57540.1 - 0.016 15.1 5.3 0.016 15.1 5.3 4.7 5 1 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Got1 PF04178.12 OIR57541.1 - 5.9e-14 52.4 18.1 7.3e-14 52.2 18.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family SUR7 PF06687.12 OIR57541.1 - 0.01 15.5 6.8 0.012 15.2 6.8 1.3 1 0 0 1 1 1 0 SUR7/PalI family Phage_holin_3_6 PF07332.11 OIR57541.1 - 4.2 7.5 16.1 0.14 12.2 4.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Cnd1 PF12717.7 OIR57542.1 - 9.1e-06 25.8 0.3 2.6e-05 24.3 0.3 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OIR57542.1 - 0.0017 17.0 1.8 0.0037 15.9 0.5 1.9 2 0 0 2 2 2 1 Adaptin N terminal region SSPI PF14098.6 OIR57542.1 - 0.026 14.7 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 Small, acid-soluble spore protein I SDA1 PF05285.12 OIR57542.1 - 0.04 13.3 28.0 0.7 9.3 19.6 3.0 3 0 0 3 3 3 0 SDA1 HEAT_2 PF13646.6 OIR57542.1 - 0.12 12.7 0.1 1.1 9.7 0.1 2.5 2 1 0 2 2 2 0 HEAT repeats PMT PF02366.18 OIR57543.1 - 9.3e-69 231.7 13.5 9.3e-69 231.7 13.5 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OIR57543.1 - 2.8e-50 170.7 5.9 2.8e-50 170.7 5.9 2.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OIR57543.1 - 2.4e-19 69.9 0.0 3.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 MIR domain TbpB_B_D PF01298.18 OIR57544.1 - 0.39 11.1 7.2 0.5 10.8 0.0 2.8 2 0 0 2 2 2 0 C-lobe and N-lobe beta barrels of Tf-binding protein B Sld5 PF05916.11 OIR57544.1 - 7.7 7.0 11.2 0.55 10.7 2.9 3.4 3 2 0 3 3 3 0 GINS complex protein PIG-P PF08510.12 OIR57545.1 - 1.1e-09 38.3 3.1 3.7e-09 36.5 3.1 1.8 1 1 0 1 1 1 1 PIG-P 2TM PF13239.6 OIR57545.1 - 0.023 15.0 0.3 0.052 13.8 0.3 1.5 1 1 1 2 2 2 0 2TM domain TMEM187 PF15100.6 OIR57545.1 - 0.065 12.8 0.3 0.071 12.7 0.3 1.1 1 0 0 1 1 1 0 TMEM187 protein family SNF2_N PF00176.23 OIR57546.1 - 8.4e-67 225.3 0.2 1.4e-66 224.6 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 OIR57546.1 - 1e-27 97.1 20.9 1e-27 97.1 20.9 3.0 3 1 1 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 OIR57546.1 - 1.9e-18 66.8 0.3 6.2e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR57546.1 - 5.3e-10 39.6 0.2 7.2e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OIR57546.1 - 0.0003 20.1 1.2 0.013 14.7 0.0 3.2 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DUF4020 PF13212.6 OIR57546.1 - 0.0024 17.7 2.6 0.0069 16.2 2.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4020) DUF1117 PF06547.12 OIR57546.1 - 0.043 14.4 5.4 1.6 9.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) XisI PF08869.11 OIR57547.1 - 0.0052 17.1 0.1 0.0083 16.5 0.1 1.4 1 1 0 1 1 1 1 XisI protein KH_8 PF17903.1 OIR57548.1 - 1.1e-17 63.9 1.7 1.1e-17 63.8 0.1 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 OIR57548.1 - 0.0057 16.5 2.7 0.01 15.6 1.6 1.9 2 0 0 2 2 2 1 KH domain Dimer_Tnp_Tn5 PF02281.16 OIR57548.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain ApoB100_C PF12491.8 OIR57548.1 - 0.073 13.0 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal SmAKAP PF15127.6 OIR57548.1 - 5.1 8.4 8.7 0.35 12.1 3.0 2.1 2 1 0 2 2 2 0 Small membrane A-kinase anchor protein LSM14 PF12701.7 OIR57549.1 - 7.6e-12 45.2 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 OIR57549.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF747 PF05346.11 OIR57550.1 - 4.6e-19 69.0 6.6 7e-19 68.4 6.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Abi_C PF14355.6 OIR57550.1 - 0.0098 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Abortive infection C-terminus PAP2 PF01569.21 OIR57550.1 - 0.27 11.0 6.0 1.8 8.3 0.5 2.5 1 1 1 2 2 2 0 PAP2 superfamily Mak10 PF04112.13 OIR57551.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase MMR_HSR1 PF01926.23 OIR57552.1 - 0.019 15.0 0.1 0.71 10.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Oxysterol_BP PF01237.18 OIR57553.1 - 7.1e-69 232.4 0.0 1.7e-68 231.1 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein GOLD_2 PF13897.6 OIR57553.1 - 3.6e-10 40.5 0.3 5.2e-07 30.2 0.3 2.7 1 1 0 1 1 1 1 Golgi-dynamics membrane-trafficking PH PF00169.29 OIR57553.1 - 0.0013 19.2 0.1 0.0043 17.5 0.1 1.9 1 1 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 OIR57553.1 - 0.033 14.3 0.3 0.93 9.6 0.1 2.9 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology RNA_pol_A_bac PF01000.26 OIR57554.1 - 1.6e-24 86.4 0.0 2.5e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OIR57554.1 - 5.1e-16 57.9 0.0 8.4e-16 57.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Med4 PF10018.9 OIR57555.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Disulph_isomer PF06491.11 OIR57555.1 - 0.17 12.0 0.0 0.73 9.9 0.0 1.8 1 1 0 1 1 1 0 Disulphide isomerase Fe_hyd_lg_C PF02906.14 OIR57556.1 - 3.9e-11 43.1 0.0 5.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF4252 PF14060.6 OIR57556.1 - 0.018 15.0 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Tubulin PF00091.25 OIR57557.1 - 5.3e-68 229.1 0.0 8.5e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OIR57557.1 - 7.5e-40 136.0 0.0 1.1e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OIR57557.1 - 0.00013 22.2 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OIR57557.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain DENN PF02141.21 OIR57558.1 - 0.00025 21.0 0.4 0.0005 20.1 0.1 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain Avl9 PF09794.9 OIR57558.1 - 0.0059 15.4 0.1 0.18 10.5 0.0 2.6 2 1 0 2 2 2 1 Transport protein Avl9 Rad52_Rad22 PF04098.15 OIR57559.1 - 6e-43 146.4 0.0 7.3e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Acetyltransf_2 PF00797.17 OIR57559.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 N-acetyltransferase Acetyltransf_10 PF13673.7 OIR57560.1 - 5.7e-11 42.4 0.1 6.7e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OIR57560.1 - 2.1e-10 40.9 0.1 2.4e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OIR57560.1 - 9.3e-07 29.2 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OIR57560.1 - 0.0054 16.7 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 OIR57560.1 - 0.027 14.6 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PC4 PF02229.16 OIR57561.1 - 7.3e-21 73.6 1.3 1.2e-20 72.9 1.3 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) SAS-6_N PF16531.5 OIR57562.1 - 8.2e-13 48.8 0.0 2.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal ATG16 PF08614.11 OIR57562.1 - 0.22 11.7 48.5 3 8.0 14.0 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 OIR57562.1 - 0.61 10.5 49.2 0.84 10.1 9.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF4201 PF13870.6 OIR57562.1 - 8.9 6.0 44.4 0.15 11.7 26.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Vps55 PF04133.14 OIR57563.1 - 0.0023 17.9 6.3 0.0027 17.7 6.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Ycf4 PF02392.16 OIR57563.1 - 0.073 12.6 0.6 0.1 12.2 0.5 1.4 1 1 0 1 1 1 0 Ycf4 Oxysterol_BP PF01237.18 OIR57564.1 - 6.3e-125 416.9 0.0 1.2e-124 416.0 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 OIR57564.1 - 2e-10 41.1 0.6 6e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 OIR57564.1 - 1.4e-05 25.3 0.1 8.9e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 OIR57564.1 - 0.012 16.0 1.7 0.4 11.1 1.7 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 OIR57564.1 - 0.036 13.9 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 PH domain Prefoldin PF02996.17 OIR57565.1 - 2.1e-14 53.4 0.0 2.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit IFT20 PF14931.6 OIR57565.1 - 0.086 13.0 0.6 0.38 10.9 0.2 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CHDCT2 PF08074.11 OIR57565.1 - 0.19 11.9 0.3 12 6.0 0.1 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain TolA_bind_tri PF16331.5 OIR57565.1 - 0.24 11.5 2.8 0.67 10.1 0.5 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Pkinase PF00069.25 OIR57566.1 - 9e-27 94.1 0.0 1.1e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57566.1 - 1.8e-13 50.4 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR57566.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OIR57566.1 - 0.031 13.1 0.0 0.04 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase UQ_con PF00179.26 OIR57567.1 - 2.8e-41 140.5 0.0 3.1e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57567.1 - 0.00042 20.0 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B VEK-30 PF12107.8 OIR57567.1 - 1.1 9.3 3.9 1.8 8.6 3.9 1.4 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway HSP70 PF00012.20 OIR57568.1 - 2.4e-234 779.0 11.3 2.8e-234 778.8 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OIR57568.1 - 1.9e-14 53.2 3.9 6.8e-13 48.1 3.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 OIR57568.1 - 0.0007 20.0 2.0 2.9 8.4 0.0 3.4 3 0 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 OIR57568.1 - 0.0055 16.4 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 OIR57568.1 - 0.026 13.8 0.1 0.097 11.9 0.1 2.0 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Synaptobrevin PF00957.21 OIR57569.1 - 2.3e-06 27.3 0.0 2.6e-06 27.1 0.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Collectrin PF16959.5 OIR57569.1 - 0.0046 16.7 0.0 0.0054 16.5 0.0 1.0 1 0 0 1 1 1 1 Renal amino acid transporter Orf78 PF06024.12 OIR57569.1 - 0.018 15.3 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) DUF5345 PF17280.2 OIR57569.1 - 0.058 13.4 0.1 0.089 12.8 0.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5345) OppC_N PF12911.7 OIR57569.1 - 0.062 13.3 0.7 0.096 12.7 0.7 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2207 PF09972.9 OIR57569.1 - 0.067 11.9 0.0 0.068 11.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4448 PF14610.6 OIR57569.1 - 0.079 12.7 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2116 PF09889.9 OIR57569.1 - 0.11 12.5 0.4 0.18 11.8 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Shisa PF13908.6 OIR57569.1 - 0.16 12.2 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1068 PF06364.12 OIR57570.1 - 0.038 13.9 0.2 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) dCMP_cyt_deam_1 PF00383.23 OIR57571.1 - 4.2e-20 71.5 0.5 6.1e-20 71.0 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OIR57571.1 - 7.9e-15 54.8 0.0 9.3e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC4_like PF18774.1 OIR57571.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.6 2 0 0 2 2 2 1 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 OIR57571.1 - 0.003 17.7 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 OIR57571.1 - 0.003 17.7 0.1 0.0041 17.2 0.1 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 OIR57571.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 APOBEC3 APOBEC2 PF18772.1 OIR57571.1 - 0.012 15.7 0.2 0.021 14.9 0.0 1.5 2 0 0 2 2 2 0 APOBEC2 Bd3614-deam PF14439.6 OIR57571.1 - 0.034 14.2 0.8 0.13 12.4 0.6 1.8 1 1 1 2 2 2 0 Bd3614-like deaminase NAD1 PF18778.1 OIR57571.1 - 0.048 13.8 0.1 0.082 13.0 0.0 1.5 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 OIR57571.1 - 0.11 12.3 0.1 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 APOBEC-like N-terminal domain Lipase_GDSL PF00657.22 OIR57572.1 - 0.00038 20.5 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ras PF00071.22 OIR57573.1 - 2.3e-45 154.1 0.0 2.8e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR57573.1 - 6.5e-21 74.8 0.0 8.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR57573.1 - 1.7e-05 24.4 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 OIR57573.1 - 0.0055 16.1 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OIR57573.1 - 0.039 14.3 0.0 0.066 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OIR57573.1 - 0.059 13.5 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 OIR57573.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Rep_fac-A_C PF08646.10 OIR57574.1 - 1.4e-05 24.9 2.8 2.2e-05 24.2 0.4 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OIR57574.1 - 0.00083 19.2 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 Replication protein A OB domain Rad50_zn_hook PF04423.14 OIR57574.1 - 0.0091 15.8 0.3 0.042 13.7 0.1 2.3 2 0 0 2 2 2 1 Rad50 zinc hook motif Vps39_2 PF10367.9 OIR57574.1 - 0.065 13.7 0.2 0.22 12.0 0.2 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.6 OIR57574.1 - 0.13 12.1 2.0 0.37 10.6 2.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Sec7 PF01369.20 OIR57575.1 - 3.7e-46 157.1 0.0 1.8e-45 154.9 0.0 2.2 1 0 0 1 1 1 1 Sec7 domain AAA PF00004.29 OIR57576.1 - 1.1e-43 148.8 0.0 2.2e-30 105.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OIR57576.1 - 6.5e-13 49.4 0.4 6.8e-05 23.3 0.0 2.9 3 1 0 3 3 2 2 AAA ATPase domain RuvB_N PF05496.12 OIR57576.1 - 2e-10 40.7 0.0 0.00013 21.8 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OIR57576.1 - 8.6e-09 35.8 1.8 0.0066 16.7 0.1 3.6 2 1 1 4 4 4 2 AAA domain AAA_33 PF13671.6 OIR57576.1 - 5.6e-08 33.1 0.0 0.003 17.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OIR57576.1 - 1e-07 31.9 0.0 0.012 15.4 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 OIR57576.1 - 2.2e-07 31.3 0.1 0.0068 16.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 OIR57576.1 - 3.2e-07 29.9 0.0 0.013 14.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_lid_3 PF17862.1 OIR57576.1 - 3.5e-07 29.9 0.0 9.3e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OIR57576.1 - 7e-07 29.3 0.3 0.0082 16.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OIR57576.1 - 7e-07 29.0 1.5 0.22 11.1 0.0 3.6 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 OIR57576.1 - 1.2e-06 28.1 0.3 0.0051 16.2 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OIR57576.1 - 2e-06 27.5 0.0 0.064 12.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 OIR57576.1 - 2e-06 28.1 0.0 0.079 13.4 0.0 2.4 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 OIR57576.1 - 2.6e-06 28.0 0.0 0.034 14.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.12 OIR57576.1 - 4.7e-06 26.6 0.2 0.06 13.3 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_17 PF13207.6 OIR57576.1 - 6.3e-06 26.7 0.0 0.019 15.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 OIR57576.1 - 1e-05 24.9 0.0 0.0019 17.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 OIR57576.1 - 1.6e-05 24.2 0.0 0.028 13.6 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Rad17 PF03215.15 OIR57576.1 - 2.1e-05 24.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain NB-ARC PF00931.22 OIR57576.1 - 2.7e-05 23.5 0.0 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_18 PF13238.6 OIR57576.1 - 3.1e-05 24.5 0.0 0.15 12.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 OIR57576.1 - 3.3e-05 23.9 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 OIR57576.1 - 7.8e-05 22.9 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ResIII PF04851.15 OIR57576.1 - 8.3e-05 22.7 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.16 OIR57576.1 - 0.00012 21.1 0.0 0.053 12.4 0.0 2.2 2 0 0 2 2 2 1 AFG1-like ATPase Sigma54_activat PF00158.26 OIR57576.1 - 0.00014 21.6 0.0 0.15 11.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 OIR57576.1 - 0.00025 20.5 0.3 0.66 9.4 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein AAA_14 PF13173.6 OIR57576.1 - 0.0003 20.8 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OIR57576.1 - 0.00039 20.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 OIR57576.1 - 0.0006 19.6 0.1 0.095 12.4 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OIR57576.1 - 0.00062 19.5 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OIR57576.1 - 0.0007 20.1 0.1 0.077 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 OIR57576.1 - 0.00088 18.4 0.0 0.084 11.9 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 SKI PF01202.22 OIR57576.1 - 0.0012 19.0 0.1 2.4 8.2 0.0 2.8 3 0 0 3 3 3 1 Shikimate kinase Cytidylate_kin2 PF13189.6 OIR57576.1 - 0.0019 18.4 0.0 0.05 13.7 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family Bac_DnaA PF00308.18 OIR57576.1 - 0.0019 18.1 0.0 1.9 8.2 0.0 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein TniB PF05621.11 OIR57576.1 - 0.002 17.6 0.0 0.51 9.7 0.0 2.6 2 0 0 2 2 2 1 Bacterial TniB protein PduV-EutP PF10662.9 OIR57576.1 - 0.0028 17.4 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 OIR57576.1 - 0.0051 16.2 0.0 1.2 8.5 0.0 2.6 3 0 0 3 3 2 1 KaiC AAA_11 PF13086.6 OIR57576.1 - 0.019 14.8 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 OIR57576.1 - 0.02 14.6 0.1 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 OIR57576.1 - 0.03 14.2 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_3 PF07726.11 OIR57576.1 - 0.047 13.6 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 OIR57576.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.8 2 1 0 2 2 1 0 Zonular occludens toxin (Zot) T2SSE PF00437.20 OIR57576.1 - 0.072 12.1 0.0 8.1 5.4 0.0 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OIR57576.1 - 0.074 12.8 0.1 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 OIR57576.1 - 0.094 12.4 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 OIR57576.1 - 0.1 12.0 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IPT PF01745.16 OIR57576.1 - 0.11 11.9 0.1 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase RsgA_GTPase PF03193.16 OIR57576.1 - 0.12 12.3 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activ_2 PF14532.6 OIR57576.1 - 0.14 12.3 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 OIR57576.1 - 0.2 12.0 0.3 4.1 7.7 0.1 2.6 3 0 0 3 3 2 0 AAA domain SYS1 PF09801.9 OIR57577.1 - 3e-09 37.2 7.3 6.1e-09 36.2 7.3 1.5 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TMEM208_SND2 PF05620.11 OIR57577.1 - 2.1 8.1 4.1 16 5.2 0.1 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 TB2_DP1_HVA22 PF03134.19 OIR57577.1 - 8.8 6.3 11.0 7.8 6.5 4.1 2.2 2 0 0 2 2 2 0 TB2/DP1, HVA22 family PPTA PF01239.22 OIR57578.1 - 6e-18 64.0 9.9 1.3e-05 24.7 1.5 4.6 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat Ribosom_S12_S23 PF00164.25 OIR57579.1 - 6.6e-46 154.6 0.7 8.6e-46 154.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ComJ PF11033.8 OIR57579.1 - 0.22 11.2 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Competence protein J (ComJ) DCP2 PF05026.13 OIR57580.1 - 8.7e-21 74.0 4.9 8.7e-21 74.0 4.9 1.6 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 OIR57580.1 - 2.3e-16 60.0 0.0 4.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DREPP PF05558.12 OIR57580.1 - 0.044 13.7 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Ribosomal_S7 PF00177.21 OIR57581.1 - 5.3e-25 87.8 0.3 5.9e-25 87.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L6e PF01159.19 OIR57581.1 - 0.034 14.7 0.1 0.041 14.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L6e EIF_2_alpha PF07541.12 OIR57582.1 - 1.5e-32 112.1 0.1 1.5e-32 112.1 0.1 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OIR57582.1 - 1.8e-07 31.4 0.7 3.4e-07 30.5 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain ABC_membrane_2 PF06472.15 OIR57582.1 - 0.17 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 zf-C3HC4_3 PF13920.6 OIR57583.1 - 5.4e-06 26.2 8.3 1e-05 25.3 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57583.1 - 3.6e-05 23.8 7.1 0.0002 21.4 5.6 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger Zn_Tnp_IS1595 PF12760.7 OIR57583.1 - 0.012 15.5 0.5 0.046 13.7 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain FYVE_2 PF02318.16 OIR57583.1 - 0.013 15.7 6.8 0.021 15.0 6.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-Di19 PF05605.12 OIR57583.1 - 0.048 14.0 8.3 0.47 10.8 3.0 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR57583.1 - 0.073 13.0 8.3 0.19 11.7 7.8 2.0 1 1 1 2 2 2 0 zinc-RING finger domain DUF2058 PF09831.9 OIR57583.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DZR PF12773.7 OIR57583.1 - 0.17 11.9 6.5 3.6 7.7 6.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 OIR57583.1 - 0.39 10.9 7.3 3.6 7.8 7.5 2.3 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OIR57583.1 - 0.44 10.6 5.3 0.46 10.5 3.7 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 OIR57583.1 - 0.55 10.1 14.2 1.4 8.8 9.2 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.19 OIR57583.1 - 1.7 8.7 8.2 1.3 9.1 2.6 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 OIR57583.1 - 1.9 8.6 7.5 11 6.1 0.1 2.7 2 1 0 2 2 2 0 BED zinc finger DUF4451 PF14616.6 OIR57583.1 - 3 8.1 10.8 1 9.5 3.0 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4451) zf-C3HC4_3 PF13920.6 OIR57584.1 - 0.0024 17.7 5.5 0.0046 16.8 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR57584.1 - 0.06 13.7 9.1 0.12 12.7 9.1 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OIR57584.1 - 0.073 12.9 6.3 0.13 12.2 6.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Reg_prop PF07494.11 OIR57584.1 - 0.74 10.2 2.0 55 4.5 0.0 4.1 4 0 0 4 4 4 0 Two component regulator propeller zf-RING_5 PF14634.6 OIR57584.1 - 2.1 8.4 8.0 4.3 7.4 7.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Stc1 PF12898.7 OIR57584.1 - 6.2 7.5 6.4 1.5 9.4 1.0 2.2 1 1 1 2 2 2 0 Stc1 domain zf-C3HC4_3 PF13920.6 OIR57585.1 - 0.00046 20.0 5.6 0.001 18.9 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OIR57585.1 - 0.13 12.1 5.6 0.49 10.2 5.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 OIR57585.1 - 0.67 10.3 5.6 1.8 8.9 1.7 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR57585.1 - 0.67 10.0 5.1 3.6 7.6 5.0 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OIR57585.1 - 1.5 9.0 5.7 0.29 11.3 1.8 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 OIR57585.1 - 1.8 8.7 5.6 13 5.9 5.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon TnpV PF14198.6 OIR57586.1 - 0.00015 21.7 7.0 5 7.2 1.7 4.9 3 1 2 5 5 5 2 Transposon-encoded protein TnpV DUF3860 PF12976.7 OIR57586.1 - 0.00026 20.9 0.5 45 4.2 0.0 6.3 5 1 2 7 7 7 0 Domain of Unknown Function with PDB structure (DUF3860) Sep15_SelM PF08806.11 OIR57586.1 - 0.0069 16.5 8.8 7.4 6.8 0.0 5.4 5 0 0 5 5 5 1 Sep15/SelM redox domain Reg_prop PF07494.11 OIR57586.1 - 0.0088 16.2 0.4 23 5.7 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller Gemini_AL1_M PF08283.11 OIR57586.1 - 0.034 14.2 1.5 7.4 6.7 0.0 3.6 4 1 0 4 4 4 0 Geminivirus rep protein central domain ANAPC15 PF15243.6 OIR57586.1 - 0.086 13.2 11.2 13 6.3 0.3 5.4 6 1 1 7 7 7 0 Anaphase-promoting complex subunit 15 Nuc_sug_transp PF04142.15 OIR57586.1 - 0.25 10.5 2.6 9.7 5.3 0.0 3.0 2 1 1 3 3 3 0 Nucleotide-sugar transporter EIF_2_alpha PF07541.12 OIR57586.1 - 0.29 11.2 3.3 57 3.8 0.1 4.4 4 2 1 5 5 5 0 Eukaryotic translation initiation factor 2 alpha subunit Inp1 PF12634.7 OIR57587.1 - 0.16 12.0 0.1 0.29 11.1 0.1 1.4 1 1 0 1 1 1 0 Inheritance of peroxisomes protein 1 Phage_holin_1 PF04531.13 OIR57588.1 - 0.06 13.9 0.3 0.2 12.2 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin TnpV PF14198.6 OIR57588.1 - 0.44 10.6 2.9 4.2 7.4 0.1 3.2 2 1 2 4 4 4 0 Transposon-encoded protein TnpV Reg_prop PF07494.11 OIR57589.1 - 5.5e-06 26.0 0.2 1.1e+02 3.6 0.0 7.8 8 0 0 8 8 8 0 Two component regulator propeller zf-C3HC4_3 PF13920.6 OIR57589.1 - 0.00031 20.5 5.9 0.00075 19.3 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57589.1 - 0.00089 19.3 2.8 0.0083 16.2 4.0 1.9 2 0 0 2 2 2 1 Zinc-binding RING-finger GcrA PF07750.11 OIR57589.1 - 0.003 18.0 0.6 22 5.4 0.0 5.8 6 1 0 6 6 6 0 GcrA cell cycle regulator Unpaired PF15972.5 OIR57589.1 - 0.22 11.0 3.1 7 6.1 0.0 4.0 4 1 1 5 5 5 0 Unpaired protein Lectin_C PF00059.21 OIR57589.1 - 0.24 12.2 2.8 1.2e+02 3.4 0.0 5.3 6 0 0 6 6 6 0 Lectin C-type domain FYVE_2 PF02318.16 OIR57589.1 - 0.26 11.5 7.6 1.1 9.5 7.6 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger Nuc_sug_transp PF04142.15 OIR57589.1 - 0.59 9.2 8.2 5.2 6.1 0.0 4.7 6 0 0 6 6 6 0 Nucleotide-sugar transporter zf-RING_4 PF14570.6 OIR57589.1 - 1.1 9.1 6.6 24 4.8 6.7 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR57589.1 - 2.3 8.2 6.3 5.3 7.1 6.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain GcrA PF07750.11 OIR57590.1 - 1.3e-05 25.7 1.7 1.1e+02 3.1 0.0 8.7 10 1 0 11 11 11 0 GcrA cell cycle regulator Reg_prop PF07494.11 OIR57590.1 - 3.7e-05 23.4 18.2 9.3 6.9 0.1 11.0 15 0 0 15 15 15 1 Two component regulator propeller TnpV PF14198.6 OIR57590.1 - 0.0087 16.0 30.1 0.12 12.3 0.4 9.3 7 3 1 9 9 9 3 Transposon-encoded protein TnpV zf-C3HC4_3 PF13920.6 OIR57590.1 - 0.015 15.1 7.4 0.031 14.1 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57590.1 - 0.069 13.3 6.4 0.17 12.0 6.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger LRR_8 PF13855.6 OIR57590.1 - 0.9 9.4 5.3 88 3.0 0.1 5.1 5 0 0 5 5 5 0 Leucine rich repeat Reg_prop PF07494.11 OIR57591.1 - 0.023 14.9 0.2 4.6 7.8 0.0 3.3 3 0 0 3 3 3 0 Two component regulator propeller Biliv-reduc_cat PF09166.10 OIR57591.1 - 0.025 14.9 0.5 6.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Biliverdin reductase, catalytic TnpV PF14198.6 OIR57591.1 - 0.16 12.0 11.8 0.21 11.6 1.2 3.3 2 1 2 4 4 4 0 Transposon-encoded protein TnpV CRS1_YhbY PF01985.21 OIR57591.1 - 0.19 11.9 3.7 4.8 7.4 0.1 3.8 1 1 2 4 4 4 0 CRS1 / YhbY (CRM) domain Terminase_5 PF06056.12 OIR57591.1 - 0.29 11.0 1.7 18 5.3 0.0 3.0 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) GED PF02212.18 OIR57593.1 - 0.12 12.6 8.9 2.7 8.2 2.5 2.4 1 1 1 2 2 2 0 Dynamin GTPase effector domain DUF1851 PF08906.11 OIR57593.1 - 0.43 10.6 6.1 93 3.1 6.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1851) COMMD1_N PF17221.3 OIR57593.1 - 2.8 8.3 4.0 9.6 6.6 0.5 2.1 1 1 0 1 1 1 0 COMMD1 N-terminal domain Helicase_C PF00271.31 OIR57594.1 - 6.5e-13 49.0 0.0 2.5e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OIR57594.1 - 8.6e-08 32.1 0.0 2.8e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OIR57594.1 - 6.4e-05 23.6 0.2 6.4e-05 23.6 0.2 2.7 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 OIR57594.1 - 0.00073 19.6 0.0 0.0054 16.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Keratin_B2_2 PF13885.6 OIR57595.1 - 1 9.3 10.0 0.42 10.6 3.8 2.2 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Ribosomal_S19e PF01090.19 OIR57597.1 - 2.1e-33 114.9 0.0 2.4e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF2922 PF11148.8 OIR57597.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) Pho88 PF10032.9 OIR57598.1 - 2.5e-45 154.0 0.1 2.9e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF5396 PF17374.2 OIR57599.1 - 0.12 10.3 0.0 0.13 10.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5396) SUI1 PF01253.22 OIR57600.1 - 5.5e-25 87.7 1.1 7.7e-25 87.2 1.1 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 GPI-anchored PF10342.9 OIR57601.1 - 0.00024 21.8 0.2 0.029 15.1 0.0 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ATP-synt_ab PF00006.25 OIR57602.1 - 6.6e-70 235.1 0.0 1.2e-69 234.2 0.0 1.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OIR57602.1 - 1.1e-06 29.1 0.1 2.3e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 OIR57602.1 - 0.2 10.5 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) RRM_1 PF00076.22 OIR57603.1 - 3.3e-11 42.9 0.2 1.6e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OIR57603.1 - 0.0036 16.9 0.0 0.87 9.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OIR57603.1 - 0.12 12.4 0.1 0.65 10.0 0.0 2.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif GDP_Man_Dehyd PF16363.5 OIR57604.1 - 4.7e-146 486.4 0.0 5.3e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OIR57604.1 - 1.2e-71 241.0 0.1 1.6e-71 240.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OIR57604.1 - 7.5e-05 22.0 0.0 0.00031 20.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OIR57604.1 - 0.00042 19.5 0.0 0.00067 18.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OIR57604.1 - 0.05 12.8 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein zf-RING_4 PF14570.6 OIR57605.1 - 1.6e-18 66.2 12.2 2.8e-18 65.4 12.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 OIR57605.1 - 1.4e-08 34.4 0.1 3.4e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OIR57605.1 - 9.9e-05 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-C3HC4_3 PF13920.6 OIR57605.1 - 0.00052 19.8 11.4 0.0012 18.7 11.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 OIR57605.1 - 0.0011 19.7 0.1 0.0026 18.4 0.1 1.6 1 0 0 1 1 1 1 Torus domain Baculo_IE-1 PF05290.11 OIR57605.1 - 0.0011 18.9 6.0 0.002 18.1 6.0 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 OIR57605.1 - 0.003 17.4 13.1 0.0062 16.4 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR57605.1 - 0.0031 17.8 12.0 0.006 16.9 12.0 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 OIR57605.1 - 0.0049 16.3 1.7 0.008 15.6 1.7 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 OIR57605.1 - 0.018 14.9 10.4 0.34 10.8 10.9 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nup35_RRM PF05172.13 OIR57605.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-ACC PF17848.1 OIR57605.1 - 0.051 13.6 4.1 3.5 7.8 0.6 2.7 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-CCCH_2 PF14608.6 OIR57605.1 - 0.067 13.7 2.2 0.17 12.4 2.2 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-UDP PF14569.6 OIR57605.1 - 0.16 12.1 10.1 0.071 13.2 7.2 2.0 2 1 0 2 2 1 0 Zinc-binding RING-finger zf-Di19 PF05605.12 OIR57605.1 - 0.17 12.2 5.6 2.2 8.6 0.1 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR57605.1 - 0.29 11.1 12.6 0.62 10.1 12.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OIR57605.1 - 0.4 10.8 9.4 2.3 8.3 9.6 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OIR57605.1 - 0.51 10.2 12.9 1.1 9.2 12.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 OIR57605.1 - 1.1 9.5 6.0 2.2 8.5 6.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger DUF3039 PF11238.8 OIR57605.1 - 2.5 7.9 7.4 2.6 7.9 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-C3HC4_4 PF15227.6 OIR57605.1 - 7.1 6.9 12.1 35 4.7 12.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING OATP PF03137.20 OIR57606.1 - 0.14 10.4 0.0 0.16 10.3 0.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RabGAP-TBC PF00566.18 OIR57607.1 - 2.9e-37 128.4 0.0 2.8e-36 125.2 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain BROMI PF14961.6 OIR57607.1 - 0.00042 17.9 0.0 0.00072 17.1 0.0 1.3 1 0 0 1 1 1 1 Broad-minded protein LapA_dom PF06305.11 OIR57608.1 - 1.5 8.7 3.1 0.72 9.7 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glucosamine_iso PF01182.20 OIR57609.1 - 2.8e-47 161.5 0.0 3.6e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF4549 PF15082.6 OIR57611.1 - 0.023 14.5 0.7 0.035 13.9 0.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) DUF4798 PF16055.5 OIR57611.1 - 2.3 8.5 6.4 2.7 8.3 2.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4798) DUF1090 PF06476.12 OIR57612.1 - 0.13 12.4 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Ribosomal_S30 PF04758.14 OIR57613.1 - 9.8e-22 76.9 5.1 1.2e-21 76.7 5.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 SNase PF00565.17 OIR57614.1 - 8.4e-25 87.4 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TadZ_N PF16968.5 OIR57615.1 - 0.085 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Prefoldin PF02996.17 OIR57616.1 - 1.9e-12 47.1 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OIR57616.1 - 0.0021 18.0 4.3 0.058 13.3 3.6 2.3 2 1 0 2 2 2 1 Prefoldin subunit FTA4 PF13093.6 OIR57616.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MerR-DNA-bind PF09278.11 OIR57616.1 - 0.021 15.4 0.0 0.4 11.3 0.0 2.1 2 0 0 2 2 2 0 MerR, DNA binding Aurora-A_bind PF09041.10 OIR57616.1 - 0.09 12.9 0.2 2.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Aurora-A binding P34-Arc PF04045.14 OIR57617.1 - 5.1e-05 23.1 0.0 0.00018 21.3 0.0 1.9 1 1 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF4843 PF16132.5 OIR57617.1 - 0.16 11.6 0.4 7.8 6.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4843) DnaJ_C PF01556.18 OIR57618.1 - 9.4e-28 97.2 0.5 1.4e-27 96.6 0.5 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OIR57618.1 - 8.1e-24 83.5 0.3 1.4e-23 82.7 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OIR57618.1 - 2.4e-10 40.6 23.8 5.2e-10 39.5 23.8 1.6 1 0 0 1 1 1 1 DnaJ central domain zf-RING_10 PF16685.5 OIR57618.1 - 1.4 9.1 12.7 2.8 8.2 2.9 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 OIR57618.1 - 1.7 8.8 9.4 4.9 7.3 9.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon CTV_P23 PF04808.12 OIR57618.1 - 1.9 8.0 4.7 0.39 10.2 0.5 1.8 1 1 1 2 2 2 0 Citrus tristeza virus (CTV) P23 protein RecR PF02132.15 OIR57618.1 - 2.1 8.0 12.7 0.26 10.9 2.7 2.8 3 0 0 3 3 3 0 RecR protein Hydrolase_4 PF12146.8 OIR57619.1 - 3.6e-09 36.3 0.0 8.1e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OIR57619.1 - 6.4e-05 22.5 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OIR57619.1 - 0.0015 18.2 0.0 0.28 10.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 OIR57619.1 - 0.0064 16.3 0.6 1 9.1 0.0 2.5 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase DUF2666 PF10869.8 OIR57619.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Methyltrans_RNA PF04452.14 OIR57620.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase DUF2157 PF09925.9 OIR57621.1 - 9.8e-05 22.2 16.0 0.00047 20.0 3.6 2.3 1 1 0 2 2 2 2 Predicted membrane protein (DUF2157) PglL_A PF15864.5 OIR57621.1 - 2.9 7.7 6.9 0.53 10.1 2.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Acyl_transf_3 PF01757.22 OIR57621.1 - 4 6.4 28.7 27 3.7 28.9 1.9 1 1 0 1 1 1 0 Acyltransferase family DUF4271 PF14093.6 OIR57621.1 - 7.1 6.5 34.7 1 9.3 15.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) MgtE PF01769.16 OIR57621.1 - 8.5 6.8 24.8 0.68 10.3 1.0 3.1 1 1 2 3 3 3 0 Divalent cation transporter DUF2070 PF09843.9 OIR57621.1 - 8.9 4.5 22.5 13 3.9 22.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NPL4 PF05021.15 OIR57622.1 - 1.6e-68 231.3 0.0 2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 OIR57622.1 - 7.8e-41 139.6 0.1 1.4e-40 138.8 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zinc_ribbon_2 PF13240.6 OIR57622.1 - 0.13 12.0 1.1 0.5 10.2 1.1 2.1 1 0 0 1 1 1 0 zinc-ribbon domain TetR_C_14 PF17754.1 OIR57622.1 - 0.19 11.6 0.3 0.38 10.7 0.3 1.3 1 0 0 1 1 1 0 MftR C-terminal domain Ephrin_rec_like PF07699.13 OIR57622.1 - 0.55 10.0 7.4 0.073 12.9 2.2 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-RanBP PF00641.18 OIR57622.1 - 9.3 5.7 7.7 0.26 10.6 0.8 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PCI PF01399.27 OIR57623.1 - 4e-16 59.4 0.3 1e-15 58.1 0.0 1.8 2 0 0 2 2 2 1 PCI domain RPN6_N PF18055.1 OIR57623.1 - 5.7e-14 52.5 0.1 5.7e-14 52.5 0.1 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_MalT PF17874.1 OIR57623.1 - 1.2e-05 24.9 1.6 1.2e-05 24.9 1.6 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 OIR57623.1 - 0.0019 18.4 2.2 0.0019 18.4 2.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OIR57623.1 - 0.0047 16.9 0.3 23 5.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_24 PF13412.6 OIR57623.1 - 0.012 15.2 0.7 0.035 13.7 0.1 2.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding TPR_19 PF14559.6 OIR57623.1 - 0.031 14.8 7.8 0.67 10.5 1.6 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat HTH_AsnC-type PF13404.6 OIR57623.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain DS PF01916.17 OIR57623.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Deoxyhypusine synthase TPR_16 PF13432.6 OIR57623.1 - 0.16 12.6 1.8 1.7 9.4 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ICAT PF06384.11 OIR57623.1 - 0.73 10.1 5.8 0.47 10.7 0.7 2.6 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT TPR_14 PF13428.6 OIR57623.1 - 1.1 10.3 4.4 13 7.0 0.1 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat MIP PF00230.20 OIR57624.1 - 8e-38 130.4 18.3 1.9e-22 80.1 8.5 2.0 2 0 0 2 2 2 2 Major intrinsic protein KH_6 PF15985.5 OIR57625.1 - 1.2e-12 48.0 0.0 2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 KH domain CAF1C_H4-bd PF12265.8 OIR57626.1 - 6.3e-23 80.8 1.1 2.1e-22 79.1 0.5 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OIR57626.1 - 3.2e-20 72.1 6.7 0.00071 20.3 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_M48 PF01435.18 OIR57627.1 - 2e-19 70.2 0.0 3.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 OIR57627.1 - 0.0014 17.9 0.2 0.0028 16.9 0.2 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 OIR57627.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Dcc1 PF09724.9 OIR57629.1 - 1.1e-21 77.5 1.0 6.6e-21 75.0 1.0 1.8 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Myb_DNA-binding PF00249.31 OIR57630.1 - 4.3e-26 90.8 5.2 1.4e-12 47.6 2.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR57630.1 - 1.5e-19 70.0 3.4 1.1e-13 51.2 0.2 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OIR57630.1 - 0.0032 17.8 2.7 0.098 13.0 0.1 2.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OIR57630.1 - 0.004 17.5 1.7 0.004 17.5 1.7 3.4 2 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OIR57630.1 - 0.056 13.7 0.1 0.72 10.1 0.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OIR57630.1 - 0.22 11.4 6.3 0.24 11.3 0.0 3.1 2 2 1 3 3 3 0 Myb DNA-binding like Spore_III_AB PF09548.10 OIR57630.1 - 0.41 10.7 3.3 1.6 8.8 0.6 2.3 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HD_5 PF13487.6 OIR57631.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 HD domain Syntaxin-18_N PF10496.9 OIR57631.1 - 0.22 11.8 3.2 2.4 8.4 0.3 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus PUF PF00806.19 OIR57632.1 - 2.2e-35 118.3 8.5 6.4e-05 22.4 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat PDEase_I PF00233.19 OIR57633.1 - 1.7e-21 77.0 0.2 3.3e-18 66.3 0.0 3.3 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 OIR57633.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 HD domain GSDH PF07995.11 OIR57633.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase RRM_1 PF00076.22 OIR57634.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4982 PF16355.5 OIR57634.1 - 0.072 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) HD_5 PF13487.6 OIR57635.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 HD domain Syntaxin-18_N PF10496.9 OIR57635.1 - 0.22 11.8 3.2 2.4 8.4 0.3 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus PUF PF00806.19 OIR57636.1 - 2.2e-35 118.3 8.5 6.4e-05 22.4 0.0 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Elf1 PF05129.13 OIR57637.1 - 3.6e-21 75.0 5.6 3.9e-21 74.9 5.6 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 OIR57637.1 - 0.0005 20.4 2.0 0.00067 20.0 2.0 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Vps36-NZF-N PF16988.5 OIR57637.1 - 0.0017 17.7 1.3 0.0017 17.7 1.3 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain NMD3 PF04981.13 OIR57637.1 - 0.0043 16.6 1.4 0.0043 16.6 1.4 1.1 1 0 0 1 1 1 1 NMD3 family TF_Zn_Ribbon PF08271.12 OIR57637.1 - 0.025 14.1 1.7 0.038 13.5 1.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.17 OIR57637.1 - 0.029 14.3 2.3 0.035 14.0 2.3 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Zn_Tnp_IS1595 PF12760.7 OIR57637.1 - 0.12 12.4 5.4 0.15 12.1 5.4 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OIR57637.1 - 0.14 12.1 3.2 0.18 11.8 3.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 OIR57637.1 - 0.14 12.3 4.5 0.21 11.7 4.2 1.5 1 1 0 1 1 1 0 Zinc ribbon domain tRNA-synt_1f PF01921.18 OIR57637.1 - 0.15 10.9 1.0 0.16 10.9 1.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) DNA_RNApol_7kD PF03604.13 OIR57637.1 - 0.26 11.0 7.4 0.73 9.6 7.4 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_11 PF16622.5 OIR57637.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type T4_baseplate PF12322.8 OIR57637.1 - 0.35 10.3 3.0 3.8 6.9 0.1 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein zf-Sec23_Sec24 PF04810.15 OIR57637.1 - 0.53 10.4 6.7 4.8 7.3 1.2 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 OIR57637.1 - 6.5 6.9 6.4 4 7.6 0.8 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger RRM_1 PF00076.22 OIR57638.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4982 PF16355.5 OIR57638.1 - 0.072 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) Dcc1 PF09724.9 OIR57639.1 - 1.1e-21 77.5 1.0 6.6e-21 75.0 1.0 1.8 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Myb_DNA-binding PF00249.31 OIR57640.1 - 4.4e-26 90.8 5.2 1.4e-12 47.6 2.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR57640.1 - 1.5e-19 70.0 3.4 1.1e-13 51.2 0.2 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 OIR57640.1 - 0.0032 17.8 2.7 0.098 13.0 0.1 2.9 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 OIR57640.1 - 0.004 17.5 1.7 0.004 17.5 1.7 3.4 2 1 0 3 3 3 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OIR57640.1 - 0.055 13.7 0.1 0.72 10.1 0.0 2.4 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OIR57640.1 - 0.21 11.5 6.2 0.24 11.3 0.0 3.1 2 2 2 4 4 4 0 Myb DNA-binding like Spore_III_AB PF09548.10 OIR57640.1 - 0.37 10.9 3.5 1.5 8.9 0.8 2.3 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Elf1 PF05129.13 OIR57642.1 - 3.6e-21 75.0 5.6 3.9e-21 74.9 5.6 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 OIR57642.1 - 0.0005 20.4 2.0 0.00067 20.0 2.0 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Vps36-NZF-N PF16988.5 OIR57642.1 - 0.0017 17.7 1.3 0.0017 17.7 1.3 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain NMD3 PF04981.13 OIR57642.1 - 0.0043 16.6 1.4 0.0043 16.6 1.4 1.1 1 0 0 1 1 1 1 NMD3 family TF_Zn_Ribbon PF08271.12 OIR57642.1 - 0.025 14.1 1.7 0.038 13.5 1.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.17 OIR57642.1 - 0.029 14.3 2.3 0.035 14.0 2.3 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Zn_Tnp_IS1595 PF12760.7 OIR57642.1 - 0.12 12.4 5.4 0.15 12.1 5.4 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 OIR57642.1 - 0.14 12.1 3.2 0.18 11.8 3.2 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 OIR57642.1 - 0.14 12.3 4.5 0.21 11.7 4.2 1.5 1 1 0 1 1 1 0 Zinc ribbon domain tRNA-synt_1f PF01921.18 OIR57642.1 - 0.15 10.9 1.0 0.16 10.9 1.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) DNA_RNApol_7kD PF03604.13 OIR57642.1 - 0.26 11.0 7.4 0.73 9.6 7.4 1.8 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-C2H2_11 PF16622.5 OIR57642.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type T4_baseplate PF12322.8 OIR57642.1 - 0.35 10.3 3.0 3.8 6.9 0.1 2.0 1 1 1 2 2 2 0 T4 bacteriophage base plate protein zf-Sec23_Sec24 PF04810.15 OIR57642.1 - 0.53 10.4 6.7 4.8 7.3 1.2 2.4 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 OIR57642.1 - 6.5 6.9 6.4 4 7.6 0.8 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger PDEase_I PF00233.19 OIR57643.1 - 1.7e-21 77.0 0.2 3.3e-18 66.3 0.0 3.3 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 OIR57643.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 HD domain GSDH PF07995.11 OIR57643.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Metallophos PF00149.28 OIR57644.1 - 3.9e-35 122.2 0.0 5.1e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OIR57644.1 - 0.0032 17.9 0.0 0.053 14.0 0.0 2.5 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OIR57644.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Sld5 PF05916.11 OIR57645.1 - 0.0029 18.0 0.0 0.0036 17.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Pmp3 PF01679.17 OIR57646.1 - 5.1e-09 36.2 0.1 9.9e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FUSC_2 PF13515.6 OIR57649.1 - 1.1e-10 41.7 27.1 2.5e-10 40.6 14.6 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.12 OIR57649.1 - 5.7e-08 31.8 12.3 5.7e-08 31.8 12.3 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family ArAE_2_N PF10337.9 OIR57649.1 - 0.00051 19.2 0.1 0.00098 18.3 0.1 1.4 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC-like PF12805.7 OIR57649.1 - 0.53 9.3 1.6 7.4 5.6 0.0 2.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS OST3_OST6 PF04756.13 OIR57649.1 - 4.8 6.4 7.7 3 7.1 0.1 2.8 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family Tyr_Deacylase PF02580.16 OIR57651.1 - 2.4e-35 122.2 0.1 2.6e-35 122.0 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase TatD_DNase PF01026.21 OIR57652.1 - 1e-46 159.4 0.0 1.2e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase SAP PF02037.27 OIR57653.1 - 5.6e-07 29.2 0.3 1.1e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 OIR57653.1 - 0.0034 17.3 0.6 0.01 15.7 0.6 1.9 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain NleF_casp_inhib PF16809.5 OIR57653.1 - 0.089 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 NleF caspase inhibitor Got1 PF04178.12 OIR57653.1 - 0.53 10.7 9.4 0.053 13.9 1.7 2.8 2 1 1 3 3 3 0 Got1/Sft2-like family RhodobacterPufX PF11511.8 OIR57653.1 - 4.6 6.9 5.1 18 5.0 0.2 3.3 4 0 0 4 4 4 0 Intrinsic membrane protein PufX Smg4_UPF3 PF03467.15 OIR57654.1 - 1.3e-07 31.9 1.0 2.1e-07 31.2 1.0 1.4 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.22 OIR57654.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADK PF00406.22 OIR57655.1 - 3.1e-28 98.8 0.1 4.5e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OIR57655.1 - 1e-18 68.1 0.2 1.3e-18 67.7 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OIR57655.1 - 6e-12 46.2 0.1 8.2e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR57655.1 - 1.6e-07 31.6 0.2 3.6e-07 30.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OIR57655.1 - 0.0039 17.4 0.5 0.0074 16.5 0.5 1.9 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 OIR57655.1 - 0.0074 16.2 0.1 0.053 13.4 0.0 2.0 1 1 1 2 2 2 1 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 OIR57655.1 - 0.025 14.3 0.1 0.63 9.7 0.0 2.1 1 1 0 2 2 2 0 Cytidylate kinase Hydin_ADK PF17213.3 OIR57655.1 - 0.044 14.1 0.1 0.059 13.6 0.1 1.4 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain CPT PF07931.12 OIR57655.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 OIR57655.1 - 0.062 12.5 0.3 0.65 9.1 0.2 2.0 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 OIR57655.1 - 0.073 13.5 0.1 0.17 12.3 0.1 1.7 1 1 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 OIR57655.1 - 0.12 12.6 0.4 5.1 7.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 OIR57655.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 OIR57655.1 - 0.14 11.4 0.6 6.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 OIR57655.1 - 0.14 11.9 0.9 0.36 10.5 0.2 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 OIR57655.1 - 0.14 12.1 0.3 0.6 10.0 0.3 2.0 1 1 0 1 1 1 0 NACHT domain E1-E2_ATPase PF00122.20 OIR57656.1 - 1.3e-51 174.7 0.2 1.2e-50 171.6 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OIR57656.1 - 3.9e-47 160.3 2.0 4.3e-47 160.2 0.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OIR57656.1 - 2e-22 80.6 5.5 1.9e-21 77.4 5.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OIR57656.1 - 4.4e-17 61.9 0.1 1.3e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OIR57656.1 - 1e-11 44.3 0.2 2.7e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OIR57656.1 - 3.4e-07 30.3 0.2 7.2e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OIR57656.1 - 1.9e-05 25.1 0.1 7.2e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BicD PF09730.9 OIR57657.1 - 2.2e-06 26.4 0.4 2.4e-06 26.3 0.4 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Mis14 PF08641.12 OIR57657.1 - 0.0059 16.9 0.6 0.0099 16.2 0.2 1.5 1 1 0 1 1 1 1 Kinetochore protein Mis14 like CHAD PF05235.14 OIR57657.1 - 0.058 13.4 0.9 1.4 8.9 0.4 2.4 1 1 0 2 2 2 0 CHAD domain Snf7 PF03357.21 OIR57658.1 - 1.8e-12 47.2 18.3 3.4e-12 46.3 18.3 1.4 1 0 0 1 1 1 1 Snf7 INCENP_ARK-bind PF03941.15 OIR57659.1 - 5.9e-10 38.9 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ATP-synt_C PF00137.21 OIR57661.1 - 8.2e-21 74.1 25.3 7.1e-14 51.9 7.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF2521 PF10730.9 OIR57662.1 - 0.022 14.8 0.2 0.031 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) PDDEXK_9 PF08011.11 OIR57663.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily OsmC PF02566.19 OIR57663.1 - 0.079 13.5 0.0 0.088 13.3 0.0 1.1 1 0 0 1 1 1 0 OsmC-like protein MIF4G PF02854.19 OIR57666.1 - 2.2e-19 69.9 2.3 5.1e-19 68.8 2.3 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OIR57666.1 - 1.8e-05 24.7 0.0 0.00047 20.1 0.0 3.1 3 0 0 3 3 3 1 MA3 domain DNA_pol_B_2 PF03175.13 OIR57667.1 - 0.23 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral GPDPase_memb PF10110.9 OIR57668.1 - 0.0016 17.3 0.5 0.0021 16.9 0.5 1.3 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase DUF3899 PF13038.6 OIR57668.1 - 0.04 14.4 0.5 0.04 14.4 0.5 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) Guanylate_kin PF00625.21 OIR57669.1 - 1e-36 126.3 0.0 1.2e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 OIR57669.1 - 3.6e-09 37.2 0.1 8.8e-09 36.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR57669.1 - 2.6e-06 27.6 0.1 0.0044 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OIR57669.1 - 6e-05 23.0 0.1 0.00066 19.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OIR57669.1 - 0.00011 22.5 0.1 0.00028 21.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OIR57669.1 - 0.00037 20.9 0.3 0.18 12.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain ABC_tran PF00005.27 OIR57669.1 - 0.00094 19.7 0.3 0.0025 18.3 0.0 1.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 OIR57669.1 - 0.001 18.7 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OIR57669.1 - 0.0011 19.1 0.1 0.0019 18.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 OIR57669.1 - 0.0012 19.1 0.4 0.0031 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OIR57669.1 - 0.0045 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OIR57669.1 - 0.0045 17.4 0.4 0.0059 17.0 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 OIR57669.1 - 0.0079 15.9 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 OIR57669.1 - 0.0096 16.4 0.7 0.035 14.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OIR57669.1 - 0.0097 15.6 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OIR57669.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain dNK PF01712.19 OIR57669.1 - 0.016 15.0 0.1 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2075 PF09848.9 OIR57669.1 - 0.017 14.4 0.1 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 OIR57669.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 OIR57669.1 - 0.024 14.6 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 OIR57669.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OIR57669.1 - 0.04 13.7 0.6 0.068 12.9 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase ATPase_2 PF01637.18 OIR57669.1 - 0.041 13.8 0.1 0.082 12.8 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OIR57669.1 - 0.055 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PRK PF00485.18 OIR57669.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 OIR57669.1 - 0.079 12.2 0.2 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 OIR57669.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 OIR57669.1 - 0.12 12.8 0.3 0.33 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OIR57669.1 - 0.15 12.1 0.2 0.21 11.6 0.2 1.7 1 1 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 OIR57669.1 - 0.17 11.4 0.6 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain REPA_OB_2 PF16900.5 OIR57670.1 - 1e-21 76.7 2.8 1.6e-21 76.0 1.0 2.1 2 1 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 OIR57670.1 - 2.6e-10 40.1 3.1 5.2e-08 32.8 0.2 2.7 2 1 1 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 OIR57670.1 - 0.00079 19.2 0.3 0.49 10.1 0.1 2.2 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 OIR57670.1 - 0.062 11.2 0.1 0.097 10.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DUF155 PF02582.14 OIR57672.1 - 3e-51 174.0 0.1 4.5e-51 173.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TBCC PF07986.12 OIR57673.1 - 2.3e-11 43.5 2.1 3.2e-11 43.0 2.1 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 OIR57673.1 - 0.047 14.1 0.0 0.082 13.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain PIG-U PF06728.13 OIR57674.1 - 6.7e-06 25.4 9.0 6.7e-06 25.4 9.0 2.2 2 1 0 2 2 2 2 GPI transamidase subunit PIG-U WD40 PF00400.32 OIR57675.1 - 9.7e-14 51.6 25.3 0.00024 21.8 1.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Pkinase PF00069.25 OIR57676.1 - 6.2e-34 117.6 0.0 9.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57676.1 - 2.3e-26 92.6 0.0 3.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OIR57676.1 - 1.1e-07 32.1 0.0 2.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 OIR57676.1 - 2.8e-05 24.6 0.0 7.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OIR57676.1 - 0.046 13.0 0.3 4.1 6.6 0.0 2.5 1 1 0 2 2 2 0 Kinase-like DUF5594 PF18057.1 OIR57676.1 - 0.077 12.9 0.1 0.28 11.0 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5594) Nucleoporin_N PF08801.11 OIR57677.1 - 1.7e-38 132.5 0.0 3.2e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OIR57677.1 - 1.1e-22 80.6 0.7 6.3e-21 74.8 0.7 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Ribosomal_L7Ae PF01248.26 OIR57678.1 - 7.4e-25 86.5 0.1 9.2e-25 86.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OIR57678.1 - 0.00035 20.6 0.1 0.00043 20.4 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 OIR57678.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain IP_trans PF02121.18 OIR57679.1 - 3e-84 282.5 0.1 3.6e-84 282.2 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein TFIIB PF00382.19 OIR57680.1 - 2.2e-26 91.7 0.1 2.1e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OIR57680.1 - 1.4e-11 43.7 1.7 2.6e-11 42.8 1.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding BRF1 PF07741.13 OIR57680.1 - 2.8e-10 40.5 18.7 3.2e-09 37.0 18.7 2.2 1 1 0 1 1 1 1 Brf1-like TBP-binding domain HTH_AsnC-type PF13404.6 OIR57680.1 - 0.011 15.6 0.0 0.7 9.8 0.0 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain PMT PF02366.18 OIR57681.1 - 6.7e-70 235.5 16.6 6.7e-70 235.5 16.6 1.7 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OIR57681.1 - 4.2e-33 114.6 0.1 4.2e-33 114.6 0.1 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OIR57681.1 - 2e-10 40.8 0.1 3.2e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 OIR57681.1 - 0.00064 20.0 6.9 0.00064 20.0 6.9 3.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TAF4 PF05236.14 OIR57682.1 - 1.8e-13 50.9 3.7 7.1e-08 32.5 0.0 2.5 2 1 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family Lectin_C PF00059.21 OIR57684.1 - 4.7e-05 24.1 0.4 0.64 10.8 0.0 3.4 2 1 0 3 3 3 2 Lectin C-type domain Peptidase_C48 PF02902.19 OIR57685.1 - 4.1e-22 79.1 0.3 9.5e-22 77.9 0.3 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AAA_5 PF07728.14 OIR57686.1 - 1.2e-83 278.0 0.0 1.3e-25 90.0 0.0 6.8 6 0 0 6 6 6 6 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OIR57686.1 - 1.9e-26 92.5 0.0 2.6e-09 37.0 0.0 4.9 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 OIR57686.1 - 1e-17 64.1 0.0 3e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_lid_7 PF17867.1 OIR57686.1 - 1.2e-15 57.6 0.1 0.00011 22.3 0.0 4.8 4 0 0 4 4 4 4 Midasin AAA lid domain AAA_6 PF12774.7 OIR57686.1 - 4.6e-14 52.1 0.1 0.046 12.7 0.1 7.0 6 1 0 6 6 6 3 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 OIR57686.1 - 9.1e-14 52.0 0.0 0.0096 16.3 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 OIR57686.1 - 1.6e-13 50.8 0.0 0.054 13.6 0.0 5.9 6 0 0 6 6 5 3 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 OIR57686.1 - 2.2e-13 50.9 4.9 0.00029 21.3 0.0 6.1 5 1 0 6 6 6 3 AAA ATPase domain AAA_7 PF12775.7 OIR57686.1 - 2.3e-13 50.1 0.3 4e-06 26.5 0.0 4.3 4 0 0 4 4 4 3 P-loop containing dynein motor region Sigma54_activat PF00158.26 OIR57686.1 - 8.4e-10 38.6 0.0 0.021 14.5 0.0 4.5 4 0 0 4 4 4 3 Sigma-54 interaction domain AAA_30 PF13604.6 OIR57686.1 - 1.2e-07 31.7 0.1 2 8.1 0.0 5.7 6 0 0 6 6 6 1 AAA domain AAA_22 PF13401.6 OIR57686.1 - 3.7e-07 30.5 3.7 0.07 13.4 0.0 5.7 6 0 0 6 6 5 2 AAA domain AAA_14 PF13173.6 OIR57686.1 - 4.5e-07 30.0 0.0 0.16 12.0 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 OIR57686.1 - 4e-06 27.4 0.1 8 7.0 0.0 5.3 5 0 0 5 5 4 0 AAA domain TsaE PF02367.17 OIR57686.1 - 8e-06 25.9 0.2 0.7 9.9 0.0 4.4 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 OIR57686.1 - 9.6e-06 25.9 0.0 0.99 9.8 0.0 4.6 4 0 0 4 4 4 1 RNA helicase ABC_tran PF00005.27 OIR57686.1 - 1.4e-05 25.6 0.3 0.66 10.5 0.0 5.0 5 0 0 5 5 4 1 ABC transporter T2SSE PF00437.20 OIR57686.1 - 1.6e-05 24.1 0.0 0.0028 16.8 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_25 PF13481.6 OIR57686.1 - 1.7e-05 24.5 0.0 0.62 9.6 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 OIR57686.1 - 1.7e-05 25.0 0.0 15 5.7 0.0 4.7 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 OIR57686.1 - 2.4e-05 24.3 0.9 1.4 8.8 0.0 4.3 4 0 0 4 4 4 1 NACHT domain AAA_28 PF13521.6 OIR57686.1 - 3.3e-05 24.2 0.7 22 5.2 0.0 5.1 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 OIR57686.1 - 9.7e-05 22.2 0.2 0.91 9.2 0.0 3.3 4 0 0 4 4 3 2 IstB-like ATP binding protein MCM PF00493.23 OIR57686.1 - 0.00068 18.8 0.0 0.028 13.5 0.0 2.6 3 0 0 3 3 2 1 MCM P-loop domain VWA_2 PF13519.6 OIR57686.1 - 0.00076 20.1 0.2 0.012 16.3 0.0 2.9 2 0 0 2 2 2 1 von Willebrand factor type A domain AAA_29 PF13555.6 OIR57686.1 - 0.0012 18.5 0.1 6 6.7 0.0 4.6 5 0 0 5 5 4 0 P-loop containing region of AAA domain Rad17 PF03215.15 OIR57686.1 - 0.0014 18.6 1.0 7.8 6.4 0.1 3.8 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_19 PF13245.6 OIR57686.1 - 0.0015 18.9 1.6 8.5 6.7 0.0 4.0 5 0 0 5 5 3 0 AAA domain Sigma54_activ_2 PF14532.6 OIR57686.1 - 0.0017 18.5 0.0 0.08 13.1 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain TniB PF05621.11 OIR57686.1 - 0.0028 17.1 0.0 2.6 7.4 0.0 3.7 4 0 0 4 4 4 1 Bacterial TniB protein RsgA_GTPase PF03193.16 OIR57686.1 - 0.0038 17.1 0.0 15 5.5 0.0 3.9 4 0 0 4 4 3 0 RsgA GTPase Zeta_toxin PF06414.12 OIR57686.1 - 0.004 16.5 0.0 1.6 7.9 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin VWA_CoxE PF05762.14 OIR57686.1 - 0.019 14.4 0.3 0.041 13.3 0.3 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein ATPase PF06745.13 OIR57686.1 - 0.042 13.2 0.0 31 3.8 0.0 3.9 4 0 0 4 4 4 0 KaiC PhoH PF02562.16 OIR57686.1 - 0.088 12.2 0.0 42 3.5 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein AAA_24 PF13479.6 OIR57686.1 - 0.15 11.8 0.1 42 3.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 OIR57686.1 - 0.2 11.5 2.3 34 4.3 0.1 4.1 4 0 0 4 4 4 0 NTPase DUF815 PF05673.13 OIR57686.1 - 0.21 10.7 3.1 27 3.8 0.0 3.9 5 0 0 5 5 4 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 OIR57686.1 - 1.7 9.1 16.4 23 5.4 0.0 6.2 7 0 0 7 7 5 0 AAA domain POP1 PF06978.11 OIR57687.1 - 3.2e-30 105.7 26.8 4.5e-16 59.5 0.7 2.7 3 1 1 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OIR57687.1 - 1.7e-24 86.0 0.4 5.9e-24 84.2 0.0 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T_C PF08669.11 OIR57687.1 - 3.1e-06 27.0 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF2924 PF11149.8 OIR57687.1 - 0.75 10.2 3.5 2.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Mito_carr PF00153.27 OIR57688.1 - 4e-19 68.3 13.4 1.9e-09 37.3 0.3 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein 7TM_GPCR_Srd PF10317.9 OIR57688.1 - 0.014 14.7 0.3 0.021 14.0 0.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd LRR_6 PF13516.6 OIR57689.1 - 0.0029 17.5 1.2 0.89 9.8 0.2 2.8 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 OIR57689.1 - 0.02 15.3 11.6 0.039 14.4 0.1 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OIR57689.1 - 9.7 6.0 9.1 2.7 7.8 1.5 3.1 2 1 1 3 3 3 0 Leucine rich repeat ISG65-75 PF11727.8 OIR57690.1 - 0.069 12.4 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF2254 PF10011.9 OIR57691.1 - 0.24 10.2 1.0 0.23 10.3 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF4539 PF15072.6 OIR57692.1 - 3.3e-06 27.1 0.6 0.037 14.1 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4539) TPP1 PF10341.9 OIR57692.1 - 0.014 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD tRNA_anti-codon PF01336.25 OIR57692.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Mcl1_mid PF12341.8 OIR57693.1 - 6.2e-32 111.1 0.0 8.3e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region CAP_GLY PF01302.25 OIR57694.1 - 1.3e-22 79.5 1.5 2.5e-22 78.7 1.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain TPR_12 PF13424.6 OIR57694.1 - 0.022 15.0 0.2 0.05 13.9 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3452 PF11934.8 OIR57694.1 - 0.11 12.1 2.2 0.24 10.9 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) Spc7 PF08317.11 OIR57694.1 - 0.17 10.7 35.4 0.012 14.5 18.0 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein APC1_C PF18122.1 OIR57694.1 - 0.47 10.4 2.7 1.3 8.9 2.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain WXG100 PF06013.12 OIR57694.1 - 0.59 10.4 6.5 6.9 7.0 0.2 4.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 OIR57694.1 - 1.4 9.0 17.1 7 6.7 2.0 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) TLE_N PF03920.15 OIR57694.1 - 4 7.5 9.4 0.97 9.5 0.8 3.4 2 2 1 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Fib_alpha PF08702.10 OIR57694.1 - 4.1 7.6 22.0 2.8 8.1 3.5 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 OIR57694.1 - 4.3 6.2 28.8 2.1 7.2 10.3 2.9 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Spc42p PF11544.8 OIR57694.1 - 6.7 6.8 15.0 0.3 11.1 0.7 4.3 4 2 0 4 4 4 0 Spindle pole body component Spc42p CRR7 PF12095.8 OIR57694.1 - 10 6.7 16.9 0.69 10.4 2.2 4.1 3 2 1 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Methyltransf_23 PF13489.6 OIR57695.1 - 5.1e-14 52.4 0.0 1e-13 51.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OIR57695.1 - 7.5e-14 52.3 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OIR57695.1 - 1.1e-12 48.4 0.0 2.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OIR57695.1 - 8.9e-11 42.3 0.0 2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OIR57695.1 - 6.3e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OIR57695.1 - 9.5e-06 25.2 0.0 0.0061 16.1 0.0 2.3 1 1 0 2 2 2 2 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 OIR57695.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 OIR57695.1 - 0.0022 19.0 0.0 0.0046 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OIR57695.1 - 0.013 15.0 0.2 0.077 12.5 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase DUF1492 PF07374.11 OIR57695.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) N6_Mtase PF02384.16 OIR57695.1 - 0.12 11.7 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase IF-2B PF01008.17 OIR57696.1 - 2.9e-16 59.5 0.0 3.5e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1688 PF07958.11 OIR57698.1 - 0.056 12.1 0.3 5.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1688) DUF1690 PF07956.11 OIR57701.1 - 0.0041 17.5 8.1 0.018 15.5 2.5 2.1 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) Syntaxin PF00804.25 OIR57701.1 - 0.0066 16.1 2.5 0.0066 16.1 2.5 1.9 1 1 1 2 2 2 1 Syntaxin Cytochrom_B562 PF07361.11 OIR57701.1 - 0.024 15.3 5.5 0.66 10.7 0.1 2.3 2 0 0 2 2 2 0 Cytochrome b562 DUF4635 PF15466.6 OIR57701.1 - 0.031 13.8 0.9 0.045 13.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) RecG_N PF17190.4 OIR57701.1 - 0.043 14.5 1.1 0.043 14.5 1.1 2.2 1 1 2 3 3 3 0 RecG N-terminal helical domain DUF1640 PF07798.11 OIR57701.1 - 0.17 11.9 11.2 0.24 11.4 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) ArAE_2_N PF10337.9 OIR57701.1 - 0.17 10.9 1.0 0.2 10.7 1.0 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal PIN_8 PF18476.1 OIR57701.1 - 0.18 11.6 9.6 0.31 10.9 4.3 2.0 1 1 1 2 2 2 0 PIN like domain KapB PF08810.10 OIR57701.1 - 0.2 11.9 1.4 0.44 10.7 0.4 1.9 2 0 0 2 2 2 0 Kinase associated protein B Cytochrom_C_2 PF01322.20 OIR57701.1 - 0.25 12.2 6.0 0.72 10.8 2.8 2.6 1 1 2 3 3 3 0 Cytochrome C' PEP-utilisers_N PF05524.13 OIR57701.1 - 0.26 11.5 2.9 6.1 7.1 0.1 2.4 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4407 PF14362.6 OIR57701.1 - 0.28 10.5 3.7 0.59 9.4 1.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GldM_N PF12081.8 OIR57701.1 - 0.34 11.0 7.0 1.2 9.2 4.1 2.4 2 1 0 2 2 2 0 GldM N-terminal domain Apolipoprotein PF01442.18 OIR57701.1 - 0.35 10.7 4.8 0.84 9.5 4.8 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain MAT1 PF06391.13 OIR57701.1 - 0.47 10.2 12.0 0.075 12.9 6.6 1.9 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 Goodbye PF17109.5 OIR57701.1 - 0.78 10.2 5.0 2.2 8.7 0.1 2.5 1 1 2 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF883 PF05957.13 OIR57701.1 - 3.2 8.4 6.7 22 5.8 0.4 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) GrpE PF01025.19 OIR57701.1 - 4.2 7.0 11.9 12 5.5 11.9 1.9 1 1 0 1 1 1 0 GrpE Chorein_N PF12624.7 OIR57702.1 - 1.1e-25 90.0 1.0 5e-25 87.9 0.3 2.6 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 OIR57702.1 - 2.8e-25 89.1 5.9 1.1e-20 74.2 1.0 3.7 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 OIR57702.1 - 4e-19 69.0 0.0 3.4e-16 59.4 0.0 2.7 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OIR57702.1 - 7.5e-06 25.9 9.0 0.016 15.0 0.1 3.6 4 1 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal Germane PF10646.9 OIR57702.1 - 0.24 12.2 1.2 11 6.8 0.0 3.7 4 0 0 4 4 4 0 Sporulation and spore germination THOC2_N PF16134.5 OIR57704.1 - 6.9e-38 130.7 2.3 3.3e-21 75.6 0.1 3.3 2 1 1 3 3 3 2 THO complex subunit 2 N-terminus Tho2 PF11262.8 OIR57704.1 - 5.1e-20 71.9 0.2 3.4e-10 39.6 0.0 2.8 3 0 0 3 3 3 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OIR57704.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Transcription- and export-related complex subunit DEAD PF00270.29 OIR57705.1 - 5.8e-43 146.7 0.0 1.5e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR57705.1 - 6.8e-24 84.4 0.0 1.9e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OIR57705.1 - 0.015 15.6 1.6 0.035 14.4 1.6 1.6 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Pkinase PF00069.25 OIR57706.1 - 2.6e-39 135.2 0.4 1.7e-35 122.7 0.6 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57706.1 - 3.4e-21 75.7 0.1 4.5e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR57706.1 - 3.6e-07 29.8 0.2 4.8e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR57706.1 - 0.0001 21.4 0.1 0.00013 21.0 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OIR57706.1 - 0.00059 19.5 0.5 0.42 10.2 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OIR57706.1 - 0.0019 17.6 0.1 0.034 13.5 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 OIR57706.1 - 0.0036 16.9 2.2 0.19 11.3 0.0 2.2 1 1 1 2 2 2 2 RIO1 family APH PF01636.23 OIR57706.1 - 0.033 14.1 0.1 1.2 9.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OIR57706.1 - 0.055 12.3 1.7 0.077 11.8 0.6 1.4 1 1 1 2 2 2 0 Fungal protein kinase Gln-synt_C-ter PF18318.1 OIR57706.1 - 0.12 12.2 0.1 0.32 10.9 0.1 1.6 2 0 0 2 2 2 0 Glutamine synthetase C-terminal domain Sulfatase PF00884.23 OIR57707.1 - 2.9e-43 148.4 0.2 3.8e-43 148.1 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OIR57707.1 - 3.6e-06 26.8 0.2 0.048 13.3 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 OIR57707.1 - 0.00013 20.8 0.0 0.0002 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF229) MARVEL PF01284.23 OIR57707.1 - 0.75 9.8 7.4 1 9.4 4.4 2.3 2 0 0 2 2 2 0 Membrane-associating domain ThiF PF00899.21 OIR57709.1 - 1.5e-39 135.9 0.4 2.1e-39 135.4 0.4 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OIR57709.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OIR57709.1 - 0.014 14.8 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 OIR57709.1 - 0.016 15.7 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 OIR57709.1 - 0.019 15.2 0.4 0.41 10.9 0.2 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 OIR57709.1 - 0.047 13.9 0.5 0.093 13.0 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 OIR57709.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-C3HC4_4 PF15227.6 OIR57709.1 - 6.5 7.0 8.5 1.2 9.4 0.9 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING RIBIOP_C PF04950.12 OIR57710.1 - 8.7e-63 212.5 0.0 8.7e-63 212.5 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OIR57710.1 - 2.7e-13 49.8 0.0 9.6e-13 48.0 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 OIR57710.1 - 2.4e-08 33.7 0.1 1.4e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 OIR57710.1 - 0.0086 15.6 0.5 0.078 12.4 0.1 2.2 2 0 0 2 2 2 1 Poxvirus A32 protein ATPase_2 PF01637.18 OIR57710.1 - 0.029 14.3 0.4 0.1 12.5 0.4 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 OIR57710.1 - 0.1 13.1 0.1 0.44 11.1 0.1 2.0 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OIR57710.1 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OIR57710.1 - 0.14 11.7 0.1 0.48 10.0 0.1 1.9 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FAD_binding_9 PF08021.11 OIR57712.1 - 0.038 14.2 0.1 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF5071 PF16804.5 OIR57712.1 - 0.16 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) AAA_11 PF13086.6 OIR57714.1 - 8.1e-54 183.1 1.3 1.3e-53 182.5 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 OIR57714.1 - 3.6e-50 170.4 0.0 1.3e-49 168.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OIR57714.1 - 2.1e-10 41.1 0.0 7.3e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OIR57714.1 - 3.5e-09 36.7 0.0 1.6e-07 31.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OIR57714.1 - 1.6e-08 34.6 3.2 0.029 14.1 0.0 3.9 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA PF00004.29 OIR57714.1 - 1.3e-05 25.6 0.8 0.0065 16.9 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OIR57714.1 - 1.4e-05 25.2 0.0 5.2e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OIR57714.1 - 1.5e-05 25.2 0.2 0.00011 22.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OIR57714.1 - 0.00014 21.2 0.3 0.0074 15.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OIR57714.1 - 0.0002 21.8 0.2 0.00084 19.8 0.1 2.1 2 1 0 2 2 1 1 AAA ATPase domain UvrD-helicase PF00580.21 OIR57714.1 - 0.00074 19.1 0.6 0.0043 16.6 0.7 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Smoothelin PF12510.8 OIR57714.1 - 0.018 15.1 2.7 0.046 13.8 2.7 1.7 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein Herpes_Helicase PF02689.14 OIR57714.1 - 0.022 12.7 0.0 0.03 12.2 0.0 1.1 1 0 0 1 1 1 0 Helicase UvrD_C_2 PF13538.6 OIR57714.1 - 0.029 14.2 0.2 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 OIR57714.1 - 0.045 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 OIR57714.1 - 0.05 14.2 0.3 0.45 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OIR57714.1 - 0.053 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 OIR57714.1 - 0.066 13.1 0.9 0.33 10.8 0.4 2.6 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 OIR57714.1 - 0.067 13.1 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 OIR57714.1 - 0.081 13.1 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OIR57714.1 - 0.095 13.2 0.6 0.46 11.0 0.0 2.4 2 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 OIR57714.1 - 0.17 12.3 0.0 0.63 10.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 OIR57714.1 - 2.5 8.6 0.0 2.5 8.6 0.0 3.0 1 1 2 3 3 3 0 AAA domain YacG PF03884.14 OIR57715.1 - 1e-06 28.3 0.0 3.2 7.6 0.0 5.7 7 0 0 7 7 7 3 DNA gyrase inhibitor YacG SOR PF07682.11 OIR57715.1 - 0.043 12.7 0.3 1.9 7.3 0.0 3.1 1 1 2 4 4 4 0 Sulphur oxygenase reductase STPPase_N PF16891.5 OIR57715.1 - 0.57 10.7 3.3 11 6.6 0.1 3.1 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain DEAD PF00270.29 OIR57716.1 - 1.2e-18 67.5 0.0 2.9e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR57716.1 - 1.1e-16 61.1 0.0 3.1e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OIR57716.1 - 4.4e-16 59.4 2.2 1.7e-15 57.5 2.2 2.1 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 OIR57716.1 - 2.8e-11 43.2 0.0 7.9e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 OIR57716.1 - 0.005 16.9 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit EMC3_TMCO1 PF01956.16 OIR57717.1 - 0.068 12.9 1.9 0.19 11.4 1.9 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like vATP-synt_E PF01991.18 OIR57717.1 - 0.085 12.3 3.1 0.21 11.0 3.1 1.6 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit SMC_N PF02463.19 OIR57718.1 - 1.1e-14 54.4 51.9 1.3e-13 50.9 51.9 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OIR57718.1 - 1.5e-14 55.0 6.7 1.5e-14 55.0 6.7 4.9 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 OIR57718.1 - 5e-09 36.4 1.5 0.0026 17.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OIR57718.1 - 2.7e-07 30.6 16.2 2.7e-07 30.6 16.2 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OIR57718.1 - 2.7e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MukB PF04310.12 OIR57718.1 - 0.00017 21.5 0.5 0.00017 21.5 0.5 2.4 3 0 0 3 3 3 1 MukB N-terminal ABC_tran PF00005.27 OIR57718.1 - 0.023 15.2 0.1 0.023 15.2 0.1 5.1 3 2 0 3 3 3 0 ABC transporter NPV_P10 PF05531.12 OIR57718.1 - 0.028 14.9 6.2 0.69 10.4 0.0 4.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein APS_kinase PF01583.20 OIR57718.1 - 0.046 13.6 1.2 2.2 8.1 0.1 2.9 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF725 PF05267.12 OIR57718.1 - 8.6 6.4 12.5 7.1 6.6 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF725) NusG PF02357.19 OIR57719.1 - 0.032 14.8 0.2 0.039 14.4 0.2 1.2 1 0 0 1 1 1 0 Transcription termination factor nusG BRF1 PF07741.13 OIR57719.1 - 0.078 13.3 0.3 0.09 13.1 0.3 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Darcynin PF17074.5 OIR57721.1 - 0.018 15.2 0.0 1.7 8.9 0.0 2.4 1 1 1 2 2 2 0 Darcynin, domain of unknown function Reg_prop PF07494.11 OIR57721.1 - 0.13 12.5 0.0 88 3.9 0.0 3.3 3 0 0 3 3 3 0 Two component regulator propeller Sep15_SelM PF08806.11 OIR57722.1 - 0.0086 16.2 9.8 0.57 10.4 0.0 6.4 8 0 0 8 8 8 1 Sep15/SelM redox domain FlbD PF06289.11 OIR57722.1 - 0.47 10.1 6.6 5.3 6.7 0.1 4.1 4 0 0 4 4 4 0 Flagellar and Swarming motility proteins BAH PF01426.18 OIR57723.1 - 0.047 13.5 0.1 0.26 11.2 0.1 2.4 1 1 0 1 1 1 0 BAH domain STE PF02200.16 OIR57724.1 - 2.3e-32 111.7 0.2 7.8e-32 110.0 0.1 1.7 2 0 0 2 2 2 1 STE like transcription factor HlyIII PF03006.20 OIR57724.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Haemolysin-III related PTH2 PF01981.16 OIR57725.1 - 5.2e-16 59.0 0.0 6.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Metallophos PF00149.28 OIR57726.1 - 2.2e-34 119.8 0.0 2.7e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OIR57726.1 - 6.4e-05 23.3 0.3 0.00013 22.4 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 OIR57726.1 - 0.0045 17.2 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FLYWCH PF04500.16 OIR57726.1 - 0.0072 16.4 0.2 0.016 15.3 0.2 1.6 1 0 0 1 1 1 1 FLYWCH zinc finger domain Glyco_hydro_65N PF03636.15 OIR57726.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Maf1 PF09174.10 OIR57727.1 - 4.5e-25 88.8 4.3 6.6e-24 85.0 4.3 2.0 1 1 0 1 1 1 1 Maf1 regulator BAR PF03114.18 OIR57728.1 - 3.3e-08 33.5 8.4 1.2e-07 31.6 8.4 1.8 1 1 0 1 1 1 1 BAR domain TFIID-31kDa PF02291.15 OIR57729.1 - 6e-33 113.5 0.1 6.8e-33 113.3 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 OIR57729.1 - 4.6e-05 23.7 0.0 6.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 OIR57729.1 - 0.0094 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OIR57729.1 - 0.023 15.0 0.1 0.04 14.2 0.1 1.7 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIP49_C PF17856.1 OIR57729.1 - 0.11 12.7 0.1 1 9.5 0.0 2.3 1 1 1 2 2 2 0 TIP49 AAA-lid domain Ccdc124 PF06244.12 OIR57730.1 - 2e-28 99.5 22.2 8.4e-28 97.5 22.2 1.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 OIR57730.1 - 0.00011 22.5 0.3 0.00011 22.5 0.3 2.8 2 1 0 2 2 2 1 HMG (high mobility group) box Pal1 PF08316.11 OIR57730.1 - 3.4 8.4 4.7 1.6 9.5 2.2 1.7 2 0 0 2 2 2 0 Pal1 cell morphology protein Thioredoxin PF00085.20 OIR57732.1 - 7.9e-43 144.6 3.2 3.8e-21 75.0 0.2 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 OIR57732.1 - 5.1e-28 98.2 2.1 4.9e-22 78.7 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 OIR57732.1 - 2.5e-14 53.7 0.4 6.1e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OIR57732.1 - 2.9e-09 37.1 0.1 0.00043 20.6 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 OIR57732.1 - 1.6e-07 31.2 0.1 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 OIR57732.1 - 2.1e-07 31.0 0.0 0.0047 17.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.24 OIR57732.1 - 1.1e-06 28.7 3.6 0.0015 18.7 0.1 3.3 3 1 0 3 3 2 2 Glutaredoxin Thioredoxin_9 PF14595.6 OIR57732.1 - 1.4e-05 24.9 0.0 0.0055 16.5 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin DUF836 PF05768.14 OIR57732.1 - 1.8e-05 25.0 0.5 0.031 14.7 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) OST3_OST6 PF04756.13 OIR57732.1 - 3.1e-05 23.5 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 OIR57732.1 - 0.0016 17.5 0.1 0.0053 15.8 0.1 1.8 2 0 0 2 2 2 1 Calsequestrin Redoxin PF08534.10 OIR57732.1 - 0.0019 17.9 0.1 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 OIR57732.1 - 0.011 15.8 2.0 0.6 10.2 0.1 2.7 2 0 0 2 2 2 0 Thioredoxin domain DUF953 PF06110.11 OIR57732.1 - 0.014 15.0 1.2 0.29 10.7 0.1 2.9 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TraF PF13728.6 OIR57732.1 - 0.029 14.2 0.0 0.67 9.7 0.0 2.7 3 0 0 3 3 3 0 F plasmid transfer operon protein ERp29_N PF07912.13 OIR57732.1 - 0.066 13.4 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 ERp29, N-terminal domain RRM_1 PF00076.22 OIR57733.1 - 3.2e-33 113.4 0.0 2.9e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OIR57733.1 - 6.3e-12 45.5 0.2 1.7e-06 28.1 0.1 2.8 2 2 0 2 2 2 2 RNA recognition motif DUF1866 PF08952.11 OIR57733.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 OIR57733.1 - 0.0075 16.3 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif B12-binding PF02310.19 OIR57733.1 - 0.16 12.0 0.0 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain MutS_V PF00488.21 OIR57734.1 - 1.7e-72 243.5 0.0 2.6e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 OIR57734.1 - 2.2e-32 111.6 0.2 6e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_III PF05192.18 OIR57734.1 - 8.1e-30 104.5 0.0 1.5e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OIR57734.1 - 2.6e-09 37.3 0.0 6.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 OIR57734.1 - 2.1e-07 31.3 0.0 5.9e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 OIR57734.1 - 0.023 15.2 0.1 0.069 13.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OIR57734.1 - 0.032 14.0 0.0 0.085 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RCC1 PF00415.18 OIR57735.1 - 3.3e-73 242.1 22.6 1.2e-13 51.4 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OIR57735.1 - 2.3e-38 129.2 49.2 1.1e-08 34.6 3.3 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.11 OIR57735.1 - 0.14 12.1 0.5 20 5.3 0.0 3.5 4 0 0 4 4 4 0 Beta-propeller repeat Gp_dh_C PF02800.20 OIR57736.1 - 1e-70 236.4 0.0 1.7e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OIR57736.1 - 1.2e-34 118.7 0.0 2.3e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 OIR57736.1 - 0.13 12.4 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Nop PF01798.18 OIR57738.1 - 1.9e-76 256.5 0.0 2.9e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OIR57738.1 - 1.3e-15 57.5 0.0 1.3e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RF-1 PF00472.20 OIR57738.1 - 0.0054 16.7 1.6 0.012 15.5 1.6 1.6 1 0 0 1 1 1 1 RF-1 domain Proteasom_Rpn13 PF04683.13 OIR57739.1 - 0.00064 20.2 0.0 0.00085 19.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor zf-C3HC4_5 PF17121.5 OIR57740.1 - 1.3e-16 60.2 10.0 2.6e-16 59.2 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MAT1 PF06391.13 OIR57740.1 - 7.2e-09 35.8 7.3 1.8e-08 34.5 7.4 1.6 1 1 1 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 OIR57740.1 - 0.0025 17.6 5.8 0.0039 17.0 4.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OIR57740.1 - 0.0052 16.6 5.0 0.0052 16.6 5.0 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR57740.1 - 0.0086 16.4 6.7 0.0086 16.4 6.7 1.8 2 0 0 2 2 2 1 Ring finger domain Cid2 PF09774.9 OIR57740.1 - 0.099 13.1 1.4 0.19 12.2 1.4 1.4 1 0 0 1 1 1 0 Caffeine-induced death protein 2 zf-C3HC4_4 PF15227.6 OIR57740.1 - 0.35 11.1 7.2 0.74 10.0 4.0 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OIR57740.1 - 1.9 8.5 13.0 0.52 10.3 9.0 2.2 2 1 1 3 3 3 0 zinc-RING finger domain STE PF02200.16 OIR57741.1 - 1.9e-30 105.5 0.2 3.3e-30 104.7 0.2 1.3 1 0 0 1 1 1 1 STE like transcription factor 14-3-3 PF00244.20 OIR57741.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 14-3-3 protein FHA_2 PF17913.1 OIR57742.1 - 0.0038 17.4 0.0 20 5.5 0.0 3.9 3 1 1 4 4 4 2 FHA domain PH_3 PF14593.6 OIR57742.1 - 0.038 14.1 0.1 0.092 12.9 0.1 1.6 1 0 0 1 1 1 0 PH domain zf-C3HC4_3 PF13920.6 OIR57744.1 - 0.00015 21.5 3.2 0.00032 20.5 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FHA_2 PF17913.1 OIR57744.1 - 0.0002 21.5 0.6 34 4.8 0.0 6.0 7 0 0 7 7 7 0 FHA domain MlaD PF02470.20 OIR57744.1 - 0.00089 19.5 2.1 26 5.2 0.0 5.4 6 0 0 6 6 5 0 MlaD protein zf-RING_14 PF17978.1 OIR57744.1 - 0.0043 17.5 0.4 0.017 15.5 0.4 2.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OIR57744.1 - 0.023 15.0 6.1 0.067 13.5 6.1 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 OIR57744.1 - 0.24 11.2 4.7 0.59 10.0 4.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OIR57744.1 - 0.3 11.4 2.0 1.1 9.6 2.0 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain PBP5_C PF07943.13 OIR57744.1 - 0.41 10.9 7.4 17 5.7 0.0 4.8 5 1 0 5 5 5 0 Penicillin-binding protein 5, C-terminal domain DnaJ_CXXCXGXG PF00684.19 OIR57744.1 - 0.87 10.0 5.7 0.21 12.0 2.0 1.9 2 0 0 2 2 1 0 DnaJ central domain zf-RING_5 PF14634.6 OIR57744.1 - 1 9.4 5.6 2.7 8.0 5.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_hydro_3_C PF01915.22 OIR57744.1 - 1.3 9.0 3.4 38 4.1 3.6 2.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Prok-RING_1 PF14446.6 OIR57744.1 - 2.7 8.0 6.5 0.53 10.2 1.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 OIR57744.1 - 3 8.1 13.1 0.14 12.4 2.6 4.0 6 0 0 6 6 6 0 FYVE-type zinc finger Zf_RING PF16744.5 OIR57744.1 - 3.9 7.7 8.1 1.5 8.9 2.7 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 OIR57744.1 - 4.7 7.2 6.6 7.9 6.5 5.3 2.1 2 0 0 2 2 2 0 PHD-finger MlaD PF02470.20 OIR57745.1 - 0.0039 17.4 0.1 13 6.1 0.0 3.6 3 0 0 3 3 3 2 MlaD protein FHA_2 PF17913.1 OIR57745.1 - 0.0091 16.2 0.1 21 5.5 0.1 3.7 2 1 1 3 3 3 2 FHA domain DUF4891 PF16232.5 OIR57745.1 - 0.97 10.0 3.8 10 6.7 0.2 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4891) zf-C3HC4_3 PF13920.6 OIR57746.1 - 9.5e-05 22.2 3.8 0.00017 21.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MobB PF03205.14 OIR57746.1 - 0.027 14.4 0.6 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B zf-RING_4 PF14570.6 OIR57746.1 - 0.028 14.2 5.6 0.069 12.9 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OIR57746.1 - 0.05 14.0 6.6 0.12 12.8 6.6 1.7 1 0 0 1 1 1 0 Ring finger domain DUF5028 PF16431.5 OIR57746.1 - 0.14 12.2 0.2 4.9 7.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5028) Prok-RING_4 PF14447.6 OIR57746.1 - 1 9.2 4.8 2.7 7.9 4.8 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OIR57746.1 - 1.3 8.9 7.0 3.1 7.7 7.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR57746.1 - 1.5 8.7 7.1 3.2 7.7 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 OIR57746.1 - 1.8 8.5 7.5 3.5 7.6 2.0 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OIR57746.1 - 2.1 8.3 7.0 5.3 7.0 7.0 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 OIR57746.1 - 2.3 8.2 5.9 5.5 7.0 5.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain HypA PF01155.19 OIR57746.1 - 2.3 8.2 6.0 44 4.2 6.0 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FYVE_2 PF02318.16 OIR57746.1 - 4.9 7.4 14.7 2.2 8.5 5.2 4.1 4 1 0 4 4 4 0 FYVE-type zinc finger FHA_2 PF17913.1 OIR57747.1 - 0.023 14.9 0.0 15 5.9 0.0 4.2 2 1 2 4 4 4 0 FHA domain DUF3929 PF13066.6 OIR57748.1 - 0.013 15.5 0.7 0.021 14.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) GRDA PF04723.14 OIR57748.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A EVC2_like PF12297.8 OIR57749.1 - 0.099 11.3 0.6 0.12 11.1 0.6 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Reg_prop PF07494.11 OIR57752.1 - 0.019 15.2 0.1 4 8.0 0.0 2.5 2 0 0 2 2 2 0 Two component regulator propeller Nuc_sug_transp PF04142.15 OIR57752.1 - 0.18 11.0 0.7 7.6 5.6 0.1 2.5 2 1 1 3 3 3 0 Nucleotide-sugar transporter zf-C3HC4_3 PF13920.6 OIR57753.1 - 4.4e-05 23.2 6.7 8.9e-05 22.3 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR57753.1 - 0.0017 18.5 4.7 0.0095 16.0 4.4 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger zf-Di19 PF05605.12 OIR57753.1 - 0.043 14.1 6.4 0.77 10.1 1.4 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 OIR57753.1 - 0.13 12.2 6.4 0.54 10.3 6.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 OIR57753.1 - 0.18 11.6 8.0 8.6 6.2 8.1 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 OIR57753.1 - 1.1 9.4 8.1 0.1 12.8 2.0 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 OIR57753.1 - 3.8 7.6 6.3 8.6 6.5 4.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4 PF00097.25 OIR57753.1 - 5.9 6.9 7.7 7 6.6 6.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-BED PF02892.15 OIR57753.1 - 5.9 7.0 6.0 21 5.2 0.1 3.0 2 2 0 2 2 2 0 BED zinc finger Reg_prop PF07494.11 OIR57754.1 - 3.5e-07 29.6 3.2 59 4.4 0.0 8.3 9 0 0 9 9 9 0 Two component regulator propeller DUF2110 PF09883.9 OIR57754.1 - 0.00029 20.5 1.4 1.1 8.8 0.0 4.2 3 2 1 4 4 4 2 Uncharacterized protein conserved in archaea (DUF2110) TnpV PF14198.6 OIR57754.1 - 0.00043 20.2 18.3 1.6 8.7 0.2 6.9 4 3 1 6 6 6 3 Transposon-encoded protein TnpV Lectin_C PF00059.21 OIR57754.1 - 0.0053 17.5 4.9 43 4.9 0.0 6.3 8 0 0 8 8 7 0 Lectin C-type domain MlaD PF02470.20 OIR57754.1 - 0.037 14.3 1.5 1.1e+02 3.2 0.0 5.5 5 2 1 6 6 6 0 MlaD protein Calsarcin PF05556.11 OIR57754.1 - 0.057 13.0 0.9 0.38 10.2 0.0 2.4 3 0 0 3 3 3 0 Calcineurin-binding protein (Calsarcin) DUF2714 PF10896.8 OIR57754.1 - 0.069 13.2 7.6 3 7.9 0.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2714) GTP_cyclohydro2 PF00925.20 OIR57754.1 - 0.082 12.5 0.0 0.55 9.8 0.0 2.3 1 1 0 1 1 1 0 GTP cyclohydrolase II ICAT PF06384.11 OIR57754.1 - 0.099 12.9 0.2 3.9 7.8 0.0 3.2 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT NOC3p PF07540.11 OIR57754.1 - 0.19 12.2 0.9 13 6.3 0.0 3.7 2 1 2 4 4 4 0 Nucleolar complex-associated protein CppA_N PF14506.6 OIR57754.1 - 0.21 11.7 2.8 1.3 9.2 0.1 3.6 3 2 0 3 3 3 0 CppA N-terminal Unpaired PF15972.5 OIR57754.1 - 0.56 9.7 3.1 5.4 6.5 0.4 3.2 2 1 0 3 3 3 0 Unpaired protein zf-C3HC4_3 PF13920.6 OIR57755.1 - 4.3e-05 23.3 7.3 7.3e-05 22.6 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sep15_SelM PF08806.11 OIR57755.1 - 0.00035 20.7 13.1 1.8 8.8 0.0 6.8 7 0 0 7 7 6 1 Sep15/SelM redox domain FYVE_2 PF02318.16 OIR57755.1 - 0.0038 17.4 4.0 0.012 15.8 4.0 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger zf-UDP PF14569.6 OIR57755.1 - 0.012 15.7 5.0 0.023 14.8 5.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF2714 PF10896.8 OIR57755.1 - 0.029 14.4 4.5 3.8 7.5 0.0 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF2714) Unpaired PF15972.5 OIR57755.1 - 0.035 13.6 6.2 11 5.4 0.1 5.1 3 2 0 5 5 5 0 Unpaired protein zf-RING_2 PF13639.6 OIR57755.1 - 0.037 14.4 7.8 0.074 13.4 7.8 1.6 1 0 0 1 1 1 0 Ring finger domain Terminase_5 PF06056.12 OIR57755.1 - 0.038 13.9 2.9 17 5.4 0.0 4.4 4 0 0 4 4 4 0 Putative ATPase subunit of terminase (gpP-like) LRR_8 PF13855.6 OIR57755.1 - 0.26 11.1 1.5 2.6 7.9 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat zf-RING_10 PF16685.5 OIR57755.1 - 0.44 10.7 3.4 1.2 9.3 3.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OIR57755.1 - 0.62 9.9 7.5 9 6.2 7.5 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 OIR57755.1 - 2 8.5 8.8 1.2 9.1 6.4 1.9 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 OIR57755.1 - 2.3 8.3 4.5 35 4.5 5.4 2.1 1 1 1 2 2 2 0 Double zinc ribbon Stc1 PF12898.7 OIR57755.1 - 2.4 8.8 4.0 2.1 9.0 1.0 2.2 2 0 0 2 2 2 0 Stc1 domain zf-Di19 PF05605.12 OIR57755.1 - 8 6.8 6.3 3.6 8.0 1.9 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 OIR57756.1 - 2.4e-05 24.1 6.6 4.6e-05 23.2 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2714 PF10896.8 OIR57756.1 - 0.001 19.1 0.1 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2714) RHH_5 PF07878.11 OIR57756.1 - 0.97 9.4 6.1 19 5.3 1.1 3.6 3 0 0 3 3 3 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 zf-RING_4 PF14570.6 OIR57756.1 - 3.5 7.5 7.0 60 3.6 7.0 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OIR57756.1 - 6.5 6.9 6.2 68 3.6 6.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon BAF250_C PF12031.8 OIR57757.1 - 0.011 15.0 0.1 0.95 8.7 0.0 2.6 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa Gryzun-like PF12742.7 OIR57757.1 - 0.074 13.1 1.9 1.2 9.2 0.2 3.4 3 0 0 3 3 3 0 Gryzun, putative Golgi trafficking DUF1647 PF07801.11 OIR57757.1 - 0.14 11.9 0.3 1.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1647) TnpV PF14198.6 OIR57757.1 - 2.1 8.4 9.7 0.71 9.9 0.3 4.0 3 1 2 5 5 5 0 Transposon-encoded protein TnpV E1-E2_ATPase PF00122.20 OIR57758.1 - 1.4e-25 89.9 0.9 2.5e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 OIR57758.1 - 1.2e-13 51.2 0.1 2.6e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 OIR57758.1 - 2.3e-05 24.0 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus WD40_3 PF15911.5 OIR57758.1 - 0.0087 16.0 0.1 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 WD domain, G-beta repeat BAF250_C PF12031.8 OIR57760.1 - 0.029 13.7 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Med6 PF04934.14 OIR57760.1 - 0.071 12.9 0.0 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 MED6 mediator sub complex component Nucleic_acid_bd PF13820.6 OIR57760.1 - 0.088 12.7 5.4 11 5.9 0.0 3.7 4 0 0 4 4 4 0 Putative nucleic acid-binding region Reg_prop PF07494.11 OIR57760.1 - 0.11 12.8 1.1 3.2 8.3 0.2 3.3 3 0 0 3 3 3 0 Two component regulator propeller MlaD PF02470.20 OIR57760.1 - 0.15 12.4 0.0 28 5.1 0.0 3.0 3 0 0 3 3 3 0 MlaD protein GPI-anchored PF10342.9 OIR57762.1 - 1.6e-05 25.6 0.0 0.0072 17.1 0.0 2.2 2 0 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Nop53 PF07767.11 OIR57765.1 - 0.92 8.8 22.8 1.2 8.5 22.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spt5-NGN PF03439.13 OIR57766.1 - 0.036 14.0 0.0 9.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section DUF5371 PF17341.2 OIR57767.1 - 0.2 11.9 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5371) GATase PF00117.28 OIR57768.1 - 1.2e-33 116.5 0.1 2.4e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CTP_synth_N PF06418.14 OIR57768.1 - 8.2e-30 104.0 0.0 1.1e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus Peptidase_C26 PF07722.13 OIR57768.1 - 1.5e-06 28.2 0.1 2.3e-05 24.3 0.0 2.5 1 1 1 2 2 2 1 Peptidase C26 DEAD PF00270.29 OIR57770.1 - 8.3e-47 159.2 0.0 2.8e-45 154.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR57770.1 - 2.1e-29 102.1 0.0 4e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 OIR57770.1 - 0.0031 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 OIR57770.1 - 0.059 13.7 0.0 0.41 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain Helicase_C_4 PF13871.6 OIR57770.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Mrr_cat_2 PF13156.6 OIR57770.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Cullin PF00888.22 OIR57771.1 - 3e-40 138.5 0.0 4.5e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family zf-RING_2 PF13639.6 OIR57774.1 - 2.6e-09 37.3 3.5 2.6e-09 37.3 3.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 OIR57774.1 - 4.1e-08 33.4 1.0 4.1e-08 33.4 1.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OIR57774.1 - 1.7e-07 30.8 0.7 6.8e-07 28.9 0.7 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OIR57774.1 - 1.9e-06 27.6 2.4 4.1e-06 26.5 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR57774.1 - 4.6e-06 26.4 3.1 1e-05 25.3 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OIR57774.1 - 4.8e-06 26.5 0.3 4.8e-06 26.5 0.3 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OIR57774.1 - 1.6e-05 24.7 2.0 1.6e-05 24.7 2.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OIR57774.1 - 1.9e-05 24.6 0.6 0.00013 22.0 0.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 OIR57774.1 - 4.1e-05 23.3 1.1 7.3e-05 22.5 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 OIR57774.1 - 0.0023 17.8 5.3 0.0032 17.4 0.1 2.6 3 0 0 3 3 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 OIR57774.1 - 0.0041 17.0 4.1 0.0041 17.0 4.1 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 OIR57774.1 - 0.0075 16.1 3.4 0.59 10.0 0.0 3.1 3 0 0 3 3 3 1 Rad50 zinc hook motif zf-Di19 PF05605.12 OIR57774.1 - 0.02 15.2 2.0 3.2 8.1 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TackOD1 PF18551.1 OIR57774.1 - 0.07 12.8 4.9 0.037 13.7 3.2 1.4 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 DUF2256 PF10013.9 OIR57774.1 - 0.11 12.6 0.9 4.6 7.4 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-C2H2_12 PF18112.1 OIR57774.1 - 0.23 12.0 5.8 3.8 8.1 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3H2C3 PF17122.5 OIR57774.1 - 0.55 10.3 11.1 1.6 8.8 4.9 3.1 2 1 0 2 2 2 0 Zinc-finger NS3_envE PF02723.14 OIR57774.1 - 0.69 10.0 4.2 1.7 8.8 0.1 2.6 2 1 1 3 3 3 0 Non-structural protein NS3/Small envelope protein E PHD PF00628.29 OIR57774.1 - 1.3 9.0 9.0 0.075 12.9 2.7 2.2 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.6 OIR57774.1 - 1.4 9.1 9.6 0.096 12.9 4.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OIR57774.1 - 5.8 6.8 9.3 1.1 9.0 3.9 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 OIR57775.1 - 2.1e-10 40.7 7.1 2.1e-10 40.7 7.1 2.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 OIR57775.1 - 7.2e-08 32.0 3.6 7.2e-08 32.0 3.6 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OIR57775.1 - 7.5e-08 32.1 7.8 7.5e-08 32.1 7.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OIR57775.1 - 1.3e-07 31.8 6.9 1.3e-07 31.8 6.9 2.6 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OIR57775.1 - 7.5e-07 28.9 7.1 7.5e-07 28.9 7.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OIR57775.1 - 1.1e-05 25.3 4.3 1.1e-05 25.3 4.3 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OIR57775.1 - 1.5e-05 24.8 4.2 1.5e-05 24.8 4.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OIR57775.1 - 0.0001 22.1 13.0 0.0023 17.7 4.5 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OIR57775.1 - 0.00032 20.2 3.3 0.00032 20.2 3.3 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zinc_ribbon_9 PF14369.6 OIR57775.1 - 0.00048 20.3 1.8 0.00048 20.3 1.8 3.6 4 0 0 4 4 4 1 zinc-ribbon zf-Nse PF11789.8 OIR57775.1 - 0.0071 16.1 8.9 0.02 14.7 6.0 2.6 1 1 1 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OIR57775.1 - 0.0089 16.1 4.1 0.0089 16.1 4.1 2.0 2 1 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger NOB1_Zn_bind PF08772.11 OIR57775.1 - 0.0096 16.1 2.4 0.02 15.1 0.1 2.2 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like DUF1870 PF08965.10 OIR57775.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) TackOD1 PF18551.1 OIR57775.1 - 0.12 12.0 0.5 0.12 12.0 0.5 2.5 2 1 0 2 2 2 0 Thaumarchaeal output domain 1 FYVE PF01363.21 OIR57775.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.6 2 1 0 2 2 2 0 FYVE zinc finger FANCL_C PF11793.8 OIR57775.1 - 0.63 10.3 11.0 0.065 13.4 5.5 2.3 2 1 0 2 2 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 OIR57775.1 - 0.69 10.1 7.6 0.08 13.1 2.4 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain zinc_ribbon_16 PF17034.5 OIR57775.1 - 0.89 9.8 6.9 0.21 11.8 0.8 2.6 2 1 1 3 3 3 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 OIR57775.1 - 1.3 9.1 11.2 0.49 10.5 3.6 3.0 3 1 0 3 3 2 0 Zinc-finger YdjO PF14169.6 OIR57775.1 - 1.6 8.6 8.0 2.3 8.0 0.4 3.3 3 1 0 3 3 3 0 Cold-inducible protein YdjO Prok-RING_4 PF14447.6 OIR57775.1 - 2.6 8.0 17.6 3.1 7.7 7.7 3.8 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 DZR PF12773.7 OIR57775.1 - 2.6 8.1 7.7 6.5 6.9 0.3 2.8 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 OIR57775.1 - 3.4 7.9 16.6 0.084 13.0 7.2 2.6 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 OIR57775.1 - 7.6 6.6 10.8 2.8 8.0 0.4 2.8 2 1 0 2 2 2 0 zinc-ribbons Hydrolase_4 PF12146.8 OIR57777.1 - 2.4e-13 49.9 0.0 5e-13 48.9 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OIR57777.1 - 6.8e-11 42.3 0.1 1.7e-10 41.0 0.1 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OIR57777.1 - 2.3e-05 25.1 0.0 2.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OIR57777.1 - 0.0094 15.4 0.0 0.074 12.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OIR57777.1 - 0.032 14.0 0.1 0.26 11.0 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Septin PF00735.18 OIR57778.1 - 6.9e-67 225.7 0.0 8.4e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OIR57778.1 - 0.003 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase CAF1C_H4-bd PF12265.8 OIR57780.1 - 1.6e-11 44.3 0.0 2.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 OIR57780.1 - 7.4e-09 35.8 3.4 0.0035 17.6 0.0 3.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OIR57780.1 - 5.4e-07 30.2 12.7 0.022 15.6 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 OIR57780.1 - 7.3e-06 26.0 0.3 1.3e-05 25.1 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 OIR57780.1 - 0.01 14.4 0.9 0.19 10.2 1.0 2.1 1 1 0 1 1 1 0 Cytochrome D1 heme domain SET PF00856.28 OIR57781.1 - 6.5e-20 72.2 0.4 1.8e-19 70.8 0.1 1.9 2 0 0 2 2 2 1 SET domain UCH PF00443.29 OIR57782.1 - 1.7e-43 149.0 0.0 2.3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR57782.1 - 1e-13 51.6 3.2 2.3e-12 47.1 3.2 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OIR57782.1 - 0.00016 21.3 1.7 0.025 14.1 0.5 2.5 2 1 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Profilin PF00235.19 OIR57783.1 - 4.2e-43 146.6 0.2 4.7e-43 146.5 0.2 1.0 1 0 0 1 1 1 1 Profilin Ribosomal_L5e PF17144.4 OIR57784.1 - 6.8e-57 192.0 0.6 1.7e-56 190.7 0.6 1.7 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OIR57784.1 - 7e-27 94.2 5.9 7e-27 94.2 5.9 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region zf-RING_11 PF17123.5 OIR57785.1 - 0.00019 21.1 3.9 0.00029 20.5 1.0 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 OIR57785.1 - 0.00057 20.2 5.0 0.00057 20.2 5.0 2.2 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 OIR57785.1 - 0.011 15.9 2.7 0.025 14.7 2.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 OIR57785.1 - 0.87 9.5 4.8 3 7.8 4.8 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OIR57785.1 - 2 8.5 5.7 6.4 6.9 5.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 OIR57785.1 - 3.8 7.6 8.2 7.9 6.5 7.3 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Ribosomal_S25 PF03297.15 OIR57786.1 - 4e-18 65.5 0.4 4.8e-18 65.2 0.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Proteasome PF00227.26 OIR57787.1 - 2.5e-27 95.6 0.1 3e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 OIR57788.1 - 2.9e-18 65.9 24.6 0.12 13.3 0.2 10.5 10 1 0 10 10 10 8 WD domain, G-beta repeat Ssu72 PF04722.13 OIR57790.1 - 2e-54 184.1 0.0 2.3e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.21 OIR57790.1 - 0.013 15.9 0.3 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase LRR_8 PF13855.6 OIR57791.1 - 6.9e-28 96.2 29.0 1.4e-08 34.4 0.2 5.5 3 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 OIR57791.1 - 1.1e-21 76.5 29.4 5.7e-06 26.6 0.9 6.7 3 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OIR57791.1 - 1.8e-09 37.3 9.5 0.00014 21.4 1.6 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 OIR57791.1 - 0.00031 20.9 26.7 12 6.9 0.3 8.8 6 4 2 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 OIR57791.1 - 9.7 6.5 21.7 2 8.7 0.3 6.9 8 0 0 8 8 8 0 Leucine Rich repeat DEAD PF00270.29 OIR57792.1 - 7.5e-43 146.3 0.0 2.3e-42 144.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR57792.1 - 1.3e-31 109.2 0.3 6.2e-31 107.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR57792.1 - 1.1e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OIR57792.1 - 0.0023 17.2 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 OIR57792.1 - 0.0047 17.3 0.1 0.18 12.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF3843 PF12954.7 OIR57792.1 - 0.01 14.8 0.4 0.014 14.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) AAA_22 PF13401.6 OIR57792.1 - 0.067 13.5 0.4 0.28 11.5 0.3 2.3 1 1 0 1 1 1 0 AAA domain IBN_N PF03810.19 OIR57794.1 - 6.6e-12 45.2 0.0 5.1e-10 39.1 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 OIR57794.1 - 1.5e-05 24.0 0.0 9.7e-05 21.3 0.0 2.3 3 0 0 3 3 3 1 Cse1 UTP15_C PF09384.10 OIR57794.1 - 0.0013 18.4 1.8 0.025 14.3 0.3 3.2 4 0 0 4 4 4 1 UTP15 C terminal RIX1 PF08167.12 OIR57794.1 - 0.022 14.5 0.8 0.058 13.1 0.1 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 OIR57794.1 - 1.9 6.9 4.1 4.1 5.8 0.1 3.1 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus DNA_pol_phi PF04931.13 OIR57794.1 - 3.1 5.8 13.1 9.8 4.1 5.1 3.5 4 0 0 4 4 4 0 DNA polymerase phi DUF4203 PF13886.6 OIR57795.1 - 5.2e-09 36.1 24.1 1.2e-08 34.9 24.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3959 PF13105.6 OIR57795.1 - 6.3 6.2 7.8 28 4.1 7.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Noc2 PF03715.13 OIR57796.1 - 0.0038 16.5 0.5 0.0038 16.5 0.5 2.0 1 1 0 2 2 2 1 Noc2p family Cytomega_UL20A PF05984.12 OIR57796.1 - 0.086 13.2 0.1 0.24 11.7 0.1 1.8 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein SapC PF07277.11 OIR57796.1 - 0.094 12.3 1.1 0.18 11.4 1.1 1.4 1 0 0 1 1 1 0 SapC GlutR_dimer PF00745.20 OIR57796.1 - 0.11 13.0 5.6 2.4 8.7 1.6 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain CDH1_2_SANT_HL1 PF18375.1 OIR57796.1 - 0.41 11.3 5.1 1.1 9.9 0.1 2.7 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 Got1 PF04178.12 OIR57797.1 - 6.5e-12 45.9 16.1 8e-12 45.6 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family SLATT_1 PF18181.1 OIR57797.1 - 0.23 11.4 0.9 1.4 8.8 0.1 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3592 PF12158.8 OIR57797.1 - 2 8.4 5.6 0.65 10.1 2.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) AAA_12 PF13087.6 OIR57798.1 - 1.8e-38 132.2 2.9 1.4e-37 129.2 0.2 2.9 2 1 0 2 2 2 1 AAA domain Dna2 PF08696.11 OIR57798.1 - 8.2e-35 120.5 1.8 1.9e-34 119.3 1.8 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 OIR57798.1 - 2e-24 86.8 10.1 5.7e-14 52.5 0.0 3.8 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 OIR57798.1 - 7.4e-18 65.0 0.0 6.8e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OIR57798.1 - 6.9e-12 45.6 5.2 0.0056 16.4 0.0 4.2 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 OIR57798.1 - 3.7e-10 40.3 0.2 1.4e-09 38.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.17 OIR57798.1 - 1.3e-08 35.1 0.1 2.3e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF83 Helicase_RecD PF05127.14 OIR57798.1 - 4.4e-06 26.7 0.0 1.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 OIR57798.1 - 3.6e-05 23.1 2.5 5.2e-05 22.6 0.5 2.3 2 1 0 2 2 2 1 PIF1-like helicase UvrD_C_2 PF13538.6 OIR57798.1 - 7.8e-05 22.4 0.5 0.00019 21.2 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain cobW PF02492.19 OIR57798.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OIR57798.1 - 0.0016 19.0 0.0 0.14 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OIR57798.1 - 0.0045 17.4 0.3 0.11 12.9 0.1 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OIR57798.1 - 0.01 16.2 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 OIR57798.1 - 0.014 14.4 0.1 0.029 13.4 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 OIR57798.1 - 0.025 13.8 0.0 0.094 11.9 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 OIR57798.1 - 0.027 14.4 0.2 0.1 12.5 0.2 2.1 1 0 0 1 1 1 0 NTPase DUF815 PF05673.13 OIR57798.1 - 0.044 13.0 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.14 OIR57798.1 - 0.048 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 OIR57798.1 - 0.066 13.0 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OIR57798.1 - 0.09 12.9 0.7 0.41 10.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.6 OIR57798.1 - 0.092 13.0 0.3 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4203 PF13886.6 OIR57799.1 - 5e-07 29.6 7.8 6.7e-07 29.2 7.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) FAST_1 PF06743.15 OIR57799.1 - 0.029 14.3 0.1 0.065 13.2 0.1 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 NDK PF00334.19 OIR57800.1 - 8.9e-48 161.7 0.0 1.1e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Rad51 PF08423.11 OIR57801.1 - 1.5e-119 398.0 0.1 1.9e-119 397.6 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OIR57801.1 - 8.5e-13 48.4 0.3 1.2e-12 47.9 0.3 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OIR57801.1 - 1.1e-09 38.1 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OIR57801.1 - 2.5e-07 30.3 0.1 5.7e-07 29.1 0.1 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OIR57801.1 - 0.00024 21.6 0.1 0.00068 20.2 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_22 PF13401.6 OIR57801.1 - 0.0011 19.3 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3215 PF11503.8 OIR57801.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) AAA_24 PF13479.6 OIR57801.1 - 0.047 13.4 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TFIID_30kDa PF03540.13 OIR57802.1 - 7.1e-18 64.3 0.0 1.1e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit VWA_2 PF13519.6 OIR57803.1 - 4e-17 62.8 0.0 3.3e-16 59.9 0.0 2.3 2 1 1 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 OIR57803.1 - 4.3e-07 29.9 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OIR57803.1 - 0.0087 15.9 1.6 0.031 14.2 1.6 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Ints3 PF10189.9 OIR57804.1 - 3.6e-26 91.8 0.4 7e-26 90.9 0.4 1.5 1 0 0 1 1 1 1 Integrator complex subunit 3 Wax2_C PF12076.8 OIR57804.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain TGF_beta_GS PF08515.12 OIR57805.1 - 0.024 14.1 0.3 0.078 12.5 0.3 1.8 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Herpes_LMP1 PF05297.11 OIR57805.1 - 0.82 8.8 11.2 0.97 8.6 11.2 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pmp3 PF01679.17 OIR57806.1 - 1.9e-14 53.6 9.9 2.3e-14 53.3 9.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Fungus-induced PF10917.8 OIR57806.1 - 0.23 11.8 2.8 0.21 11.9 0.7 1.9 2 0 0 2 2 2 0 Fungus-induced protein zf-C2H2_4 PF13894.6 OIR57807.1 - 8.6e-08 32.4 11.0 0.0025 18.5 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OIR57807.1 - 3.9e-07 30.1 11.5 0.0029 18.0 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OIR57807.1 - 6.2e-05 23.2 3.7 6.2e-05 23.2 3.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain C1_4 PF07975.12 OIR57807.1 - 0.02 15.1 4.2 0.18 12.0 0.1 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain zf-BED PF02892.15 OIR57807.1 - 0.023 14.7 3.1 0.023 14.7 3.1 1.8 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_11 PF16622.5 OIR57807.1 - 0.056 13.2 4.1 1.1 9.1 0.5 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-RING_7 PF02591.15 OIR57807.1 - 0.061 13.5 0.5 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-UDP PF14569.6 OIR57807.1 - 0.14 12.3 2.0 0.27 11.4 2.0 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_10 PF10058.9 OIR57807.1 - 0.15 11.8 2.0 0.4 10.5 2.0 1.7 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zinc_ribbon_9 PF14369.6 OIR57807.1 - 0.15 12.3 2.7 2.9 8.2 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon zf-C2HE PF16278.5 OIR57807.1 - 0.21 12.0 7.9 0.88 10.1 0.3 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn_ribbon_recom PF13408.6 OIR57807.1 - 0.34 11.4 2.9 0.53 10.8 2.3 1.6 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 OIR57807.1 - 0.48 10.9 5.1 2.5 8.6 0.1 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 OIR57807.1 - 0.61 10.1 4.7 1.7 8.6 0.3 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf_UBZ PF18439.1 OIR57807.1 - 2.1 8.0 5.2 4.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 OIR57807.1 - 3.9 7.7 11.1 2.2 8.5 1.5 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger Glutaredoxin PF00462.24 OIR57808.1 - 5.1e-12 45.8 0.0 1.7e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OIR57808.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin SH3BGR PF04908.15 OIR57808.1 - 0.16 12.1 0.0 0.35 11.1 0.0 1.5 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Metallophos PF00149.28 OIR57809.1 - 7.7e-35 121.3 0.1 9.6e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OIR57809.1 - 0.042 14.0 0.0 0.066 13.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 OIR57809.1 - 0.087 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 OIR57809.1 - 0.092 13.2 0.2 0.21 12.1 0.2 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-CCHC_2 PF13696.6 OIR57810.1 - 4.6e-20 71.1 12.9 2.7e-10 39.8 2.9 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 OIR57810.1 - 0.00023 21.1 7.2 0.063 13.4 0.7 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 OIR57810.1 - 0.0093 15.9 9.4 0.72 9.9 0.4 2.6 2 1 0 2 2 2 2 Zinc knuckle Endonuclease_7 PF02945.15 OIR57810.1 - 0.023 14.6 3.1 0.56 10.2 0.8 2.4 1 1 1 2 2 2 0 Recombination endonuclease VII zf-CCHC_4 PF14392.6 OIR57810.1 - 0.18 11.5 8.8 0.76 9.6 1.7 2.3 2 0 0 2 2 2 0 Zinc knuckle Copper-fist PF00649.18 OIR57810.1 - 0.22 11.1 3.8 1.1 8.8 0.6 2.3 2 0 0 2 2 2 0 Copper fist DNA binding domain His_Me_b4a2 PF18275.1 OIR57810.1 - 1.6 8.8 6.2 2.2 8.4 4.4 2.0 1 1 1 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain Ribosomal_S21e PF01249.18 OIR57811.1 - 6.9e-22 77.4 0.0 7.2e-22 77.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e DUF1610 PF07754.11 OIR57811.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Sep15_SelM PF08806.11 OIR57813.1 - 0.018 15.2 0.3 12 6.1 0.0 3.2 2 1 1 3 3 3 0 Sep15/SelM redox domain DS PF01916.17 OIR57815.1 - 1.8e-123 411.4 0.1 2.1e-123 411.2 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF1749 PF08538.10 OIR57816.1 - 5.6e-46 157.0 0.0 6.9e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OIR57816.1 - 0.0047 17.6 0.0 0.0067 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OIR57816.1 - 0.0077 15.5 0.0 0.061 12.6 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OIR57816.1 - 0.014 15.0 0.0 0.069 12.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OIR57816.1 - 0.077 12.5 0.0 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 OIR57816.1 - 0.087 12.7 0.0 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase DUF1057 PF06342.12 OIR57816.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) CD20 PF04103.15 OIR57817.1 - 0.21 11.6 0.5 0.34 11.0 0.5 1.3 1 0 0 1 1 1 0 CD20-like family CEP63 PF17045.5 OIR57818.1 - 0.024 14.5 3.4 0.04 13.8 3.4 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Spc7 PF08317.11 OIR57818.1 - 0.19 10.6 4.8 0.28 10.0 4.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RNase_PH PF01138.21 OIR57819.1 - 7.3e-15 55.6 0.0 1.2e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OIR57819.1 - 9.3e-05 22.4 0.0 0.00026 21.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Myc_N PF01056.18 OIR57820.1 - 0.0037 17.2 7.0 0.0047 16.9 7.0 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF3300 PF11737.8 OIR57820.1 - 0.031 13.8 3.6 0.042 13.4 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) DUF2052 PF09747.9 OIR57820.1 - 0.047 13.8 10.5 0.058 13.5 10.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_3_Rpc31 PF11705.8 OIR57820.1 - 0.062 13.5 13.5 0.075 13.3 13.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 OIR57820.1 - 0.097 13.1 6.5 0.16 12.4 6.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 OIR57820.1 - 0.48 9.1 8.7 0.66 8.7 8.7 1.2 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 OIR57820.1 - 0.53 8.4 13.7 0.64 8.2 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 OIR57820.1 - 0.68 9.1 3.9 0.88 8.7 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OIR57820.1 - 0.81 7.9 7.7 0.9 7.8 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 OIR57820.1 - 0.9 7.5 10.0 1.1 7.2 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 OIR57820.1 - 0.99 9.2 10.2 1.5 8.6 10.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.8 OIR57820.1 - 0.99 8.1 9.7 1.4 7.7 9.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPL5 PF18168.1 OIR57820.1 - 1 8.6 4.3 1.3 8.3 4.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 PPP4R2 PF09184.11 OIR57820.1 - 1 8.9 13.8 1.2 8.7 13.8 1.1 1 0 0 1 1 1 0 PPP4R2 TRAP_alpha PF03896.16 OIR57820.1 - 1.2 8.3 7.6 1.6 7.9 7.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 OIR57820.1 - 1.3 8.4 15.9 1.6 8.1 15.9 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 OIR57820.1 - 1.9 7.4 4.3 2.1 7.3 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pes-10 PF07149.11 OIR57820.1 - 2.7 6.9 11.5 3.4 6.6 11.5 1.1 1 0 0 1 1 1 0 Pes-10 CENP-T_N PF16171.5 OIR57820.1 - 3.1 6.6 8.6 3.7 6.4 8.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus DUF4746 PF15928.5 OIR57820.1 - 3.1 7.1 16.7 4.6 6.6 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 OIR57820.1 - 3.7 6.4 14.6 5.1 6.0 14.6 1.1 1 0 0 1 1 1 0 Paf1 CbtA PF09490.10 OIR57820.1 - 3.8 7.2 5.4 3.2 7.5 4.3 1.4 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) WRNPLPNID PF15017.6 OIR57820.1 - 5 8.1 14.9 9.8 7.1 14.9 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF908 PF06012.12 OIR57820.1 - 5.5 6.3 5.5 6.9 6.0 5.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4637 PF15470.6 OIR57820.1 - 7 6.4 14.5 12 5.6 14.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RNA_polI_A34 PF08208.11 OIR57820.1 - 7 6.7 15.2 9.2 6.3 15.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.6 OIR57820.1 - 9.2 5.9 15.3 8.8 6.0 14.1 1.6 1 1 0 1 1 1 0 FAM176 family RPN2_C PF18004.1 OIR57820.1 - 9.8 6.1 14.5 15 5.5 14.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TAP42 PF04177.12 OIR57821.1 - 1.2e-12 47.6 15.2 1.3e-09 37.7 7.8 2.4 1 1 1 2 2 2 2 TAP42-like family GNVR PF13807.6 OIR57822.1 - 0.23 11.4 0.7 0.52 10.3 0.7 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Adeno_E3_CR2 PF02439.15 OIR57822.1 - 0.56 10.0 2.9 1 9.2 2.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 S4 PF01479.25 OIR57823.1 - 2.1e-10 40.1 0.0 7.5e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 OIR57823.1 - 1.5e-05 25.8 2.2 3.4e-05 24.7 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 OIR57823.1 - 0.036 13.9 0.0 0.36 10.6 0.0 2.2 1 1 1 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain CDPS PF16715.5 OIR57823.1 - 0.16 11.6 0.5 1.9 8.1 0.1 2.2 1 1 1 2 2 2 0 Cyclodipeptide synthase ATP-synt_D PF01813.17 OIR57824.1 - 1.9e-25 89.9 1.3 2.2e-25 89.7 1.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D PVL_ORF50 PF07768.11 OIR57824.1 - 0.046 14.0 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 PVL ORF-50-like family vATP-synt_AC39 PF01992.16 OIR57825.1 - 2.6e-67 227.7 0.5 3e-67 227.5 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF705 PF05152.12 OIR57825.1 - 0.085 12.3 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF705) zf-RING_2 PF13639.6 OIR57828.1 - 0.015 15.6 4.6 0.042 14.2 4.6 1.8 1 0 0 1 1 1 0 Ring finger domain Mut7-C PF01927.16 OIR57828.1 - 0.27 11.3 3.6 0.56 10.3 3.6 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-C3HC4_2 PF13923.6 OIR57828.1 - 0.33 10.8 3.8 0.84 9.5 3.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 OIR57828.1 - 0.41 10.6 8.5 0.054 13.4 1.2 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF-5_eIF-2B PF01873.17 OIR57829.1 - 4e-36 123.4 0.2 6.8e-36 122.7 0.2 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OIR57829.1 - 9.3e-11 41.7 0.0 2.3e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_Tnp_IS1595 PF12760.7 OIR57829.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 OIR57829.1 - 0.12 11.9 1.3 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF3797 PF12677.7 OIR57829.1 - 0.2 11.6 0.7 0.49 10.3 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-TFIIB PF13453.6 OIR57829.1 - 0.21 11.0 1.8 0.41 10.0 1.8 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF4936 PF16290.5 OIR57830.1 - 0.00055 20.6 0.3 0.0014 19.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4936) AAA_13 PF13166.6 OIR57830.1 - 0.0032 16.2 7.2 0.0054 15.4 7.2 1.3 1 0 0 1 1 1 1 AAA domain OmpH PF03938.14 OIR57830.1 - 0.011 16.1 6.1 0.03 14.7 6.1 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 OIR57830.1 - 0.34 11.1 5.8 0.73 10.0 5.3 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 OIR57830.1 - 4.6 6.5 11.5 9.3 5.5 11.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.20 OIR57832.1 - 8.8e-110 367.7 8.4 8.8e-110 367.7 8.4 1.6 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 OIR57832.1 - 2e-09 36.8 9.5 7.4e-09 34.9 2.4 3.0 3 0 0 3 3 3 2 MreB/Mbl protein MnmE_helical PF12631.7 OIR57832.1 - 0.072 13.2 1.6 19 5.4 0.0 3.4 2 2 0 3 3 3 0 MnmE helical domain PH_2 PF08458.10 OIR57832.1 - 0.53 10.7 0.0 0.53 10.7 0.0 2.8 3 0 0 3 3 3 0 Plant pleckstrin homology-like region Ctf8 PF09696.10 OIR57833.1 - 6.4e-05 23.3 0.2 0.0038 17.6 0.0 2.6 1 1 2 3 3 3 2 Ctf8 XRN1_D1 PF18332.1 OIR57833.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain Methyltransf_25 PF13649.6 OIR57834.1 - 2.3e-12 47.5 0.4 1.8e-11 44.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OIR57834.1 - 4.9e-12 46.3 0.4 2.9e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OIR57834.1 - 2.1e-11 43.9 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OIR57834.1 - 6e-10 39.0 0.2 8.6e-10 38.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 OIR57834.1 - 8.2e-08 31.5 0.1 1.1e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 OIR57834.1 - 7.8e-07 29.1 0.0 4.7e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OIR57834.1 - 1.9e-05 24.3 0.2 3.4e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OIR57834.1 - 2.3e-05 23.8 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OIR57834.1 - 3.5e-05 24.5 0.1 0.00012 22.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PRMT5_C PF17286.2 OIR57834.1 - 4.6e-05 23.4 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_18 PF12847.7 OIR57834.1 - 0.00032 20.6 0.1 0.00071 19.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.16 OIR57834.1 - 0.00053 19.9 0.0 0.00082 19.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 OIR57834.1 - 0.00058 19.7 0.1 0.00087 19.1 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OIR57834.1 - 0.0015 18.7 0.1 0.0083 16.2 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OIR57834.1 - 0.0017 17.7 0.2 0.0063 15.8 0.1 1.8 2 0 0 2 2 2 1 O-methyltransferase domain TehB PF03848.14 OIR57834.1 - 0.0053 16.2 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 OIR57834.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 OIR57834.1 - 0.017 16.1 0.0 0.04 14.9 0.0 1.7 1 1 1 2 2 1 0 Methyltransferase domain UPF0020 PF01170.18 OIR57834.1 - 0.028 14.1 0.2 0.18 11.5 0.2 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 OIR57834.1 - 0.058 13.4 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 OIR57834.1 - 0.097 12.1 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.10 OIR57834.1 - 0.14 11.7 0.0 0.42 10.2 0.0 2.0 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase zf-C2H2_4 PF13894.6 OIR57836.1 - 6.6e-07 29.6 3.2 0.0026 18.4 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OIR57836.1 - 8.6e-07 29.1 3.3 0.029 14.8 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 OIR57836.1 - 0.0029 17.9 1.0 2.6 8.6 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OIR57836.1 - 0.023 15.0 1.3 0.23 11.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OIR57836.1 - 0.12 12.9 2.0 0.15 12.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 OIR57836.1 - 0.63 10.1 2.9 14 5.8 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 OIR57836.1 - 0.67 10.5 3.1 1.8 9.0 0.2 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Rotamase_3 PF13616.6 OIR57838.1 - 1.5e-17 64.2 0.1 4.8e-17 62.6 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 OIR57838.1 - 2.6e-17 63.6 0.0 3.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 OIR57838.1 - 0.0011 19.7 0.0 0.0014 19.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain AAA_16 PF13191.6 OIR57839.1 - 5e-07 30.3 0.3 1.1e-06 29.1 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 OIR57839.1 - 6e-07 29.6 0.3 5.4e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 OIR57839.1 - 1.2e-05 24.5 0.1 2.4e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 OIR57839.1 - 4.1e-05 24.0 0.3 0.00021 21.7 0.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 OIR57839.1 - 0.00021 20.9 0.1 0.00051 19.6 0.1 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_17 PF13207.6 OIR57839.1 - 0.00061 20.2 0.0 0.002 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OIR57839.1 - 0.00062 20.1 0.1 0.0035 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OIR57839.1 - 0.0013 18.7 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OIR57839.1 - 0.0015 18.3 0.4 0.0032 17.2 0.2 1.6 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 OIR57839.1 - 0.0042 17.4 0.8 0.014 15.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OIR57839.1 - 0.0053 17.3 0.2 0.0092 16.5 0.2 1.8 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 OIR57839.1 - 0.0057 16.6 0.0 0.0087 16.0 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OIR57839.1 - 0.0062 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 NTPase AAA_11 PF13086.6 OIR57839.1 - 0.0062 16.3 0.1 0.011 15.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OIR57839.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 OIR57839.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OIR57839.1 - 0.013 15.3 1.2 0.032 14.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 OIR57839.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OIR57839.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 OIR57839.1 - 0.016 15.2 0.3 0.059 13.3 0.3 2.1 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 OIR57839.1 - 0.039 13.7 0.1 0.57 9.9 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 OIR57839.1 - 0.043 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OIR57839.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OIR57839.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Kinesin PF00225.23 OIR57839.1 - 0.07 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain AAA_24 PF13479.6 OIR57839.1 - 0.084 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 OIR57839.1 - 0.092 11.9 2.0 0.11 11.6 0.2 1.9 2 1 1 3 3 3 0 G-protein alpha subunit NB-ARC PF00931.22 OIR57839.1 - 0.094 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 OIR57839.1 - 0.11 12.7 1.6 0.26 11.5 0.1 2.3 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 OIR57839.1 - 0.11 12.6 0.4 0.35 11.0 0.4 2.1 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 OIR57839.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 AIG1 family RNA_helicase PF00910.22 OIR57839.1 - 0.16 12.4 0.0 0.54 10.7 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 OIR57839.1 - 0.16 12.0 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 OIR57839.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Adap_comp_sub PF00928.21 OIR57840.1 - 7e-70 235.4 0.0 8.3e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OIR57840.1 - 1.2e-06 28.5 0.4 3.1e-06 27.2 0.4 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OIR57840.1 - 0.0022 17.5 0.0 0.038 13.4 0.0 2.1 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain CBFD_NFYB_HMF PF00808.23 OIR57841.1 - 3.4e-14 52.9 0.0 5.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OIR57841.1 - 3.9e-08 33.7 0.0 7.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mob1_phocein PF03637.17 OIR57842.1 - 3.8e-22 79.1 0.0 4.4e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family SRP68 PF16969.5 OIR57843.1 - 1.3 7.9 4.7 0.51 9.3 1.1 2.2 2 1 0 2 2 2 0 RNA-binding signal recognition particle 68 MCM PF00493.23 OIR57844.1 - 1.6e-80 269.4 0.1 1.4e-78 263.1 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 OIR57844.1 - 3.7e-24 85.0 2.0 8e-24 83.9 2.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OIR57844.1 - 4.3e-21 75.1 3.2 8.9e-21 74.1 3.2 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 OIR57844.1 - 3.5e-11 42.9 0.3 6.6e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OIR57844.1 - 7.7e-10 38.9 0.0 3.2e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OIR57844.1 - 7.7e-06 25.8 0.0 2.4e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OIR57844.1 - 0.0027 17.4 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 OIR57844.1 - 0.0057 17.1 0.1 0.036 14.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OIR57844.1 - 0.046 13.5 0.1 0.26 11.0 0.1 2.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OIR57844.1 - 0.065 13.0 0.0 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OIR57844.1 - 0.1 12.9 0.0 0.37 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain CENP-T_C PF15511.6 OIR57845.1 - 2.1e-09 37.5 0.2 2.5e-09 37.2 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OIR57845.1 - 1.5e-05 25.1 0.2 2e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 OIR57845.1 - 3.4e-05 24.1 0.1 4.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OIR57845.1 - 5.9e-05 23.4 0.4 6.7e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OIR57845.1 - 6.6e-05 23.2 0.3 9.9e-05 22.7 0.3 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 OIR57845.1 - 0.0018 18.3 0.0 0.0022 18.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Cytidylate_kin2 PF13189.6 OIR57845.1 - 0.025 14.7 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase-like family Bromo_TP PF07524.13 OIR57845.1 - 0.12 12.5 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated HIGH_NTase1_ass PF16581.5 OIR57845.1 - 0.12 12.4 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Myb_DNA-binding PF00249.31 OIR57846.1 - 0.0022 18.1 0.0 0.0061 16.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PV-1 PF06637.11 OIR57846.1 - 0.0037 16.2 1.8 0.0041 16.0 1.8 1.0 1 0 0 1 1 1 1 PV-1 protein (PLVAP) EF-hand_1 PF00036.32 OIR57848.1 - 3.7e-10 38.6 1.2 0.024 14.2 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OIR57848.1 - 5.9e-09 36.3 3.8 8e-07 29.4 1.0 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OIR57848.1 - 3.8e-08 32.6 1.7 0.026 14.4 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 OIR57848.1 - 5.5e-05 22.5 2.1 0.8 9.3 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 OIR57848.1 - 0.0096 15.8 7.1 3 7.8 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair ATPase PF06745.13 OIR57848.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 KaiC EF-hand_4 PF12763.7 OIR57848.1 - 0.053 13.5 2.3 0.4 10.7 0.4 2.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Histone PF00125.24 OIR57849.1 - 2.6e-50 170.2 4.7 2.9e-50 170.0 4.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OIR57849.1 - 0.00014 22.0 0.2 0.00027 21.0 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OIR57849.1 - 0.00016 22.0 0.1 0.00025 21.4 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OIR57849.1 - 0.00033 21.3 2.1 0.00038 21.0 2.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 OIR57849.1 - 0.066 13.3 0.3 0.13 12.3 0.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Phage_holin_3_3 PF16083.5 OIR57850.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Tubulin PF00091.25 OIR57851.1 - 5.6e-66 222.5 0.0 1.2e-65 221.4 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OIR57851.1 - 6e-33 113.7 0.0 9.2e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 OIR57851.1 - 0.019 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Misat_Tub_SegII PF10644.9 OIR57851.1 - 0.034 14.4 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain YEATS PF03366.16 OIR57853.1 - 4.5e-25 87.4 0.0 7e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family Topoisom_bac PF01131.20 OIR57854.1 - 1.5e-106 356.9 0.0 2.1e-106 356.4 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OIR57854.1 - 1.8e-17 63.4 0.0 4.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Cnd1 PF12717.7 OIR57856.1 - 6.4e-07 29.6 1.3 0.0009 19.3 0.1 2.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OIR57856.1 - 0.0026 17.9 2.3 22 5.6 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat DNA_pol3_finger PF17657.1 OIR57856.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain HEAT_2 PF13646.6 OIR57856.1 - 0.028 14.8 0.9 0.18 12.2 0.2 2.7 2 1 0 2 2 2 0 HEAT repeats Adaptin_N PF01602.20 OIR57856.1 - 0.068 11.7 0.2 0.25 9.8 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region RRM_1 PF00076.22 OIR57857.1 - 1.2e-14 53.8 0.0 2.4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFA2_Winged_2 PF18121.1 OIR57858.1 - 1.1e-06 28.2 0.0 3.2e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OIR57858.1 - 0.0031 17.8 0.1 0.0076 16.5 0.1 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain RNA_pol_N PF01194.17 OIR57859.1 - 2.8e-32 110.8 0.5 3.3e-32 110.6 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 OIR57859.1 - 0.0016 18.6 0.4 0.0021 18.3 0.4 1.2 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) CBFB_NFYA PF02045.15 OIR57860.1 - 2.8e-25 88.7 6.6 4.3e-25 88.1 5.1 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B BRCA-2_OB1 PF09103.10 OIR57862.1 - 6.5e-26 90.7 0.0 7.1e-25 87.3 0.0 2.7 3 1 0 3 3 3 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 OIR57862.1 - 5.7e-05 22.7 12.8 0.019 14.6 3.1 3.8 2 2 0 2 2 2 2 BRCA2 repeat BRCA-2_helical PF09169.10 OIR57862.1 - 0.0004 20.1 0.1 0.00078 19.2 0.1 1.4 1 0 0 1 1 1 1 BRCA2, helical MCM PF00493.23 OIR57863.1 - 4.5e-70 235.2 0.0 6.9e-70 234.6 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 OIR57863.1 - 4.8e-17 62.1 0.1 9.7e-17 61.2 0.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 OIR57863.1 - 1.2e-16 60.8 0.7 2.1e-16 59.9 0.7 1.3 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 OIR57863.1 - 9.1e-09 35.0 0.3 8.2e-07 28.6 0.0 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OIR57863.1 - 0.00026 21.0 0.0 0.00052 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OIR57863.1 - 0.13 12.6 0.4 0.43 10.9 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain cNMP_binding PF00027.29 OIR57864.1 - 1.7e-35 120.9 1.2 3.8e-19 68.6 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EF-hand_7 PF13499.6 OIR57865.1 - 8.4e-06 26.2 0.4 9.6e-05 22.8 0.1 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OIR57865.1 - 1.6e-05 24.4 0.2 8.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OIR57865.1 - 0.00011 21.5 0.0 0.0003 20.1 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OIR57865.1 - 0.0014 18.4 0.0 0.42 10.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OIR57865.1 - 0.0015 17.9 0.1 0.0033 16.8 0.1 1.6 1 0 0 1 1 1 1 EF hand PCI PF01399.27 OIR57866.1 - 1.2e-06 29.0 0.0 1.7e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 PCI domain RE_NgoFVII PF09565.10 OIR57867.1 - 5.1 6.3 12.3 0.26 10.5 0.1 2.2 1 1 1 2 2 2 0 NgoFVII restriction endonuclease DUF2605 PF10792.9 OIR57868.1 - 0.21 11.5 3.9 0.19 11.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) Rep_fac-A_C PF08646.10 OIR57869.1 - 7.1e-40 136.1 7.9 2.5e-38 131.1 6.9 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OIR57869.1 - 2.3e-22 78.7 3.5 3e-22 78.4 1.2 2.4 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 OIR57869.1 - 3.5e-10 39.7 6.8 1.1e-05 25.4 0.2 4.5 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain DUF4539 PF15072.6 OIR57869.1 - 2.6e-08 33.8 1.3 0.002 18.1 0.0 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF4539) CDC24_OB3 PF17244.2 OIR57869.1 - 1.2e-06 28.5 7.0 0.051 13.3 1.5 3.4 3 0 0 3 3 3 3 Cell division control protein 24, OB domain 3 TPP1 PF10341.9 OIR57869.1 - 0.017 15.1 0.1 0.38 10.8 0.0 2.9 3 0 0 3 3 3 0 Shelterin complex subunit, TPP1/ACD Ribosomal_L37ae PF01780.19 OIR57869.1 - 0.049 13.7 0.5 0.049 13.7 0.5 2.0 2 0 0 2 2 2 0 Ribosomal L37ae protein family DUF4224 PF13986.6 OIR57869.1 - 0.12 12.3 0.4 10 6.1 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4224) SRF-TF PF00319.18 OIR57870.1 - 5.9e-20 70.5 0.0 1e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Proteasome PF00227.26 OIR57871.1 - 4.5e-39 133.9 0.0 6.7e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR57871.1 - 6.8e-14 51.2 0.5 1.1e-13 50.6 0.5 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CheZ PF04344.13 OIR57871.1 - 0.092 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Ribosomal_L11 PF00298.19 OIR57871.1 - 0.11 13.0 0.2 4.2 7.9 0.1 2.5 2 1 0 2 2 2 0 Ribosomal protein L11, RNA binding domain Cpn60_TCP1 PF00118.24 OIR57873.1 - 1.1e-137 459.7 11.8 1.2e-137 459.5 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WaaY PF06176.11 OIR57873.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) ThiF PF00899.21 OIR57874.1 - 0.00016 21.2 0.2 0.00042 19.7 0.1 1.7 2 1 0 2 2 2 1 ThiF family Homeodomain PF00046.29 OIR57876.1 - 9.1e-18 63.9 3.1 1.4e-17 63.2 3.1 1.3 1 0 0 1 1 1 1 Homeodomain Ribosomal_L31e PF01198.19 OIR57877.1 - 6.2e-28 96.9 4.8 7.6e-28 96.6 4.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MqsA_antitoxin PF15731.5 OIR57877.1 - 0.059 13.5 0.1 0.076 13.1 0.1 1.2 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Pkinase PF00069.25 OIR57878.1 - 6.1e-51 173.3 0.0 9.1e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57878.1 - 7e-19 68.1 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR57878.1 - 0.011 15.7 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_S17e PF00833.18 OIR57879.1 - 4.2e-50 168.7 0.2 4.8e-50 168.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 NinE PF05322.11 OIR57879.1 - 0.012 15.5 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 NINE Protein RPOL_N PF14700.6 OIR57879.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal TPR_1 PF00515.28 OIR57880.1 - 5.5e-28 95.6 20.5 2e-06 27.4 0.2 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 OIR57880.1 - 2.1e-23 80.5 20.9 5.7e-05 22.9 0.2 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 OIR57880.1 - 1.1e-22 79.4 12.0 7e-09 35.2 1.6 4.6 4 1 0 4 4 4 3 TPR repeat TPR_7 PF13176.6 OIR57880.1 - 1.1e-12 47.0 12.1 0.00057 19.7 0.1 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 OIR57880.1 - 4.8e-12 46.2 11.9 5.3e-05 23.7 0.2 4.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OIR57880.1 - 1.2e-11 43.8 23.7 0.0017 18.4 0.5 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat STI1 PF17830.1 OIR57880.1 - 7.5e-11 41.8 0.9 1.8e-10 40.6 0.9 1.7 1 0 0 1 1 1 1 STI1 domain TPR_14 PF13428.6 OIR57880.1 - 2.4e-10 40.4 6.1 1 10.3 0.0 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 OIR57880.1 - 5.1e-10 39.5 16.3 3.9e-05 23.9 1.4 5.2 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 OIR57880.1 - 6.8e-10 39.4 9.7 8.8e-05 23.1 1.5 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OIR57880.1 - 6.4e-06 26.2 8.6 0.12 12.8 0.4 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR57880.1 - 8.1e-05 22.8 11.6 0.092 13.0 0.1 3.7 3 1 0 3 3 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 OIR57880.1 - 0.00021 21.1 16.0 3.3 7.7 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 OIR57880.1 - 0.0007 19.0 0.1 7.5 6.1 0.0 4.3 4 0 0 4 4 4 0 SHNi-TPR Fis1_TPR_C PF14853.6 OIR57880.1 - 0.00083 19.4 14.1 0.0024 17.9 0.1 4.1 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 OIR57880.1 - 0.0027 17.8 1.3 0.096 12.8 0.2 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 OIR57880.1 - 0.0049 17.2 8.3 1.2 9.5 0.2 3.7 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OIR57880.1 - 0.0064 17.1 15.6 14 6.6 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR PF01535.20 OIR57880.1 - 0.049 13.9 2.1 89 3.7 0.1 4.7 4 0 0 4 4 4 0 PPR repeat Rapsyn_N PF10579.9 OIR57880.1 - 0.068 13.3 1.0 2.4 8.3 0.0 3.1 2 2 2 4 4 3 0 Rapsyn N-terminal myristoylation and linker region GerD PF17898.1 OIR57880.1 - 0.083 12.8 3.1 0.12 12.3 0.6 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF3856 PF12968.7 OIR57880.1 - 0.13 12.3 8.2 4.9 7.2 1.0 3.8 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 OIR57880.1 - 0.13 12.3 0.1 0.13 12.3 0.1 5.7 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 OIR57880.1 - 0.15 11.7 18.1 1 9.1 7.4 3.7 2 2 3 5 5 5 0 Tetratricopeptide repeat-like domain SPO22 PF08631.10 OIR57880.1 - 0.84 9.1 8.7 11 5.4 0.0 4.2 4 1 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like DUF1910 PF08928.10 OIR57880.1 - 1.3 9.1 6.2 3.7 7.6 0.0 3.3 4 0 0 4 4 3 0 Domain of unknown function (DUF1910) ENTH PF01417.20 OIR57883.1 - 6.5e-31 107.0 0.0 9.2e-31 106.5 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OIR57883.1 - 0.015 14.3 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 ANTH domain DUF202 PF02656.15 OIR57884.1 - 8.1 7.0 9.1 2.1e+02 2.5 9.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Yeast-kill-tox PF09207.11 OIR57885.1 - 0.21 12.3 3.4 0.37 11.4 3.4 1.5 1 0 0 1 1 1 0 Yeast killer toxin VESA1_N PF12785.7 OIR57885.1 - 0.63 8.9 13.9 0.89 8.5 13.9 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Pkinase PF00069.25 OIR57886.1 - 5.4e-69 232.5 0.0 6.8e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57886.1 - 9.2e-35 120.2 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR57886.1 - 5.1e-05 23.3 0.0 0.011 15.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OIR57886.1 - 7.9e-05 22.3 0.2 0.0002 21.1 0.2 1.5 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 OIR57886.1 - 0.00021 20.7 0.0 0.00048 19.5 0.0 1.6 1 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 OIR57886.1 - 0.00022 20.8 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 OIR57886.1 - 0.00026 20.4 0.0 0.00054 19.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OIR57886.1 - 0.0056 15.5 0.0 0.0096 14.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OIR57886.1 - 0.029 14.0 0.1 0.055 13.1 0.1 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CoA_binding_3 PF13727.6 OIR57886.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain Choline_kinase PF01633.20 OIR57886.1 - 0.068 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PIGA PF08288.12 OIR57887.1 - 2.4e-33 114.6 0.8 4.8e-33 113.6 0.2 1.8 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OIR57887.1 - 3.1e-25 89.1 0.6 5.6e-25 88.3 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OIR57887.1 - 3e-24 85.5 0.2 2.3e-23 82.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OIR57887.1 - 1.6e-21 77.2 1.1 5.8e-21 75.3 0.3 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OIR57887.1 - 3.4e-12 47.1 0.2 1.3e-11 45.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OIR57887.1 - 5.8e-05 23.1 0.1 0.00024 21.1 0.1 1.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OIR57887.1 - 0.0013 19.1 0.1 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 BAT PF15915.5 OIR57887.1 - 0.016 15.1 0.2 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 GAF and HTH_10 associated domain Glyco_transf_5 PF08323.11 OIR57887.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Starch synthase catalytic domain tRNA-synt_2c PF01411.19 OIR57888.1 - 8.1e-185 615.5 0.0 1.3e-184 614.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OIR57888.1 - 9.1e-06 25.7 0.3 2.5e-05 24.3 0.3 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain XRN_N PF03159.18 OIR57889.1 - 4.7e-73 245.6 0.3 1.3e-70 237.6 0.0 2.8 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 OIR57889.1 - 7e-56 190.0 8.0 1.3e-41 143.1 3.0 2.4 2 0 0 2 2 2 2 Xrn1 helical domain SH3_12 PF18129.1 OIR57889.1 - 5.7e-05 23.1 0.4 0.00019 21.5 0.4 1.9 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 OIR57889.1 - 0.1 12.3 0.0 0.63 9.8 0.0 2.3 1 1 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain Beta_helix PF13229.6 OIR57889.1 - 0.12 12.2 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Right handed beta helix region NosD PF05048.13 OIR57889.1 - 0.19 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) XPG_I PF00867.18 OIR57890.1 - 2.9e-33 114.1 0.0 5.7e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 OIR57890.1 - 1.8e-26 92.5 0.0 3.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 OIR57890.1 - 1e-05 26.1 0.0 6.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.18 OIR57890.1 - 0.00041 19.9 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus HHH_5 PF14520.6 OIR57890.1 - 0.012 16.2 0.0 0.039 14.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Apolipoprotein PF01442.18 OIR57891.1 - 1.3e-05 25.2 0.6 0.00012 22.1 0.4 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Muted PF14942.6 OIR57891.1 - 0.02 15.2 4.6 0.026 14.9 4.6 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein XhlA PF10779.9 OIR57891.1 - 0.056 13.7 1.5 0.36 11.1 1.6 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF883 PF05957.13 OIR57891.1 - 0.14 12.7 1.9 2.5 8.8 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 OIR57891.1 - 0.19 12.3 3.7 1.2 9.7 0.4 2.5 1 1 1 2 2 2 0 YtxH-like protein tRNA_bind_2 PF13725.6 OIR57891.1 - 0.24 11.1 4.6 0.21 11.3 3.4 1.5 1 1 1 2 2 2 0 Possible tRNA binding domain Clathrin_propel PF01394.20 OIR57892.1 - 1e-11 44.5 0.0 0.00014 22.0 0.0 3.2 3 0 0 3 3 3 3 Clathrin propeller repeat Cullin PF00888.22 OIR57893.1 - 2.3e-06 26.6 0.0 6.9e-06 25.0 0.0 1.8 1 1 0 1 1 1 1 Cullin family PolyA_pol PF01743.20 OIR57894.1 - 1.8e-26 93.0 0.1 5.9e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OIR57894.1 - 1.2e-07 31.4 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A NPL PF17800.1 OIR57895.1 - 2.8e-18 66.4 0.0 2.8e-18 66.4 0.0 2.3 2 1 0 2 2 2 1 Nucleoplasmin-like domain SGS PF05002.15 OIR57896.1 - 7.1e-17 61.3 8.2 1.6e-16 60.2 8.2 1.6 1 1 0 1 1 1 1 SGS domain CS PF04969.16 OIR57896.1 - 0.001 20.0 0.1 0.0024 18.9 0.1 1.7 1 0 0 1 1 1 1 CS domain GspL_C PF12693.7 OIR57896.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain zinc-ribbon_6 PF10005.9 OIR57896.1 - 0.11 13.2 0.6 0.21 12.3 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain cpYpsA PF12694.7 OIR57898.1 - 0.12 12.1 1.9 2.4 7.9 0.2 2.4 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family YtxH PF12732.7 OIR57898.1 - 7.5 7.2 19.2 4.1 8.0 1.1 3.8 3 2 0 3 3 3 0 YtxH-like protein RuvC PF02075.17 OIR57899.1 - 0.11 12.3 0.2 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Pro_isomerase PF00160.21 OIR57902.1 - 4.3e-44 150.6 0.1 4.8e-44 150.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L35Ae PF01247.18 OIR57903.1 - 3.1e-34 117.0 0.3 4.7e-34 116.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae MutS_V PF00488.21 OIR57904.1 - 2.1e-72 243.1 0.1 3.8e-72 242.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OIR57904.1 - 2.8e-28 99.5 1.1 5.2e-28 98.6 1.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 OIR57904.1 - 2.8e-11 43.6 0.0 6.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 OIR57904.1 - 0.017 14.7 0.2 0.12 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain PX PF00787.24 OIR57905.1 - 2.1e-14 53.5 0.0 3.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 PX domain SlyX PF04102.12 OIR57905.1 - 0.02 15.5 1.4 0.13 12.9 1.4 2.3 1 1 0 1 1 1 0 SlyX SCIMP PF15050.6 OIR57905.1 - 0.2 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 SCIMP protein NIF PF03031.18 OIR57906.1 - 3e-21 75.8 0.3 3.5e-21 75.6 0.3 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_SAK_2 PF18143.1 OIR57906.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 1 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins NAPRTase_C PF17956.1 OIR57906.1 - 0.043 14.2 0.3 0.49 10.8 0.1 2.2 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain Daxx PF03344.15 OIR57906.1 - 0.05 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain ATP_bind_1 PF03029.17 OIR57907.1 - 1.4e-66 224.7 0.0 5.1e-57 193.4 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OIR57907.1 - 0.0016 18.5 0.0 0.0064 16.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 OIR57907.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OIR57907.1 - 0.0023 18.2 0.0 0.033 14.5 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OIR57907.1 - 0.0042 17.5 0.0 0.0078 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OIR57907.1 - 0.005 16.8 0.0 0.16 11.8 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 OIR57907.1 - 0.0057 17.1 0.0 0.016 15.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OIR57907.1 - 0.0097 16.5 0.0 0.022 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 OIR57907.1 - 0.017 14.9 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PhoH PF02562.16 OIR57907.1 - 0.023 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 OIR57907.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 OIR57907.1 - 0.043 14.3 0.0 0.075 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 OIR57907.1 - 0.044 13.5 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain UPF0225 PF17775.1 OIR57907.1 - 0.044 14.6 0.0 0.071 13.9 0.0 1.3 1 0 0 1 1 1 0 UPF0225 domain AAA_5 PF07728.14 OIR57907.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OIR57907.1 - 0.076 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OIR57907.1 - 0.088 13.2 0.0 0.27 11.6 0.0 1.8 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 OIR57907.1 - 0.1 12.3 0.0 0.56 9.9 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 OIR57907.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 OIR57907.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 OIR57907.1 - 0.16 12.3 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OIR57907.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OIR57907.1 - 0.21 11.7 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.12 OIR57908.1 - 5.1e-32 109.6 14.2 2.1e-05 25.0 0.0 8.1 7 1 0 7 7 7 7 Sel1 repeat TPR_2 PF07719.17 OIR57908.1 - 0.46 10.7 3.5 2.1 8.7 0.8 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Exo70 PF03081.15 OIR57910.1 - 3.6e-26 92.1 0.5 1.1e-25 90.6 0.1 2.0 2 1 0 2 2 2 1 Exo70 exocyst complex subunit DUF4201 PF13870.6 OIR57910.1 - 0.025 14.3 4.6 0.071 12.8 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) COG6 PF06419.11 OIR57910.1 - 0.077 11.2 8.0 0.77 7.9 0.5 2.3 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 SLX9 PF15341.6 OIR57910.1 - 1.6 9.1 5.4 11 6.4 3.4 2.6 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 BAR_3 PF16746.5 OIR57910.1 - 2.6 7.7 12.4 2.3 7.8 3.8 3.7 3 2 1 4 4 4 0 BAR domain of APPL family ubiquitin PF00240.23 OIR57911.1 - 1.5e-33 114.4 0.3 1.6e-33 114.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OIR57911.1 - 6.7e-16 57.9 0.3 7.4e-16 57.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OIR57911.1 - 2.5e-05 24.7 0.1 0.0001 22.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OIR57911.1 - 0.0029 17.9 0.0 0.0033 17.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OIR57911.1 - 0.0044 17.1 0.1 0.0089 16.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OIR57911.1 - 0.011 15.8 0.3 2.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OIR57911.1 - 0.018 15.0 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OIR57911.1 - 0.036 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain DUF2407 PF10302.9 OIR57911.1 - 0.048 14.2 0.0 0.055 14.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Methyltr_RsmB-F PF01189.17 OIR57912.1 - 1.8e-34 119.2 0.0 3.1e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OIR57912.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 OIR57912.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin NusB PF01029.18 OIR57912.1 - 0.056 13.7 0.3 0.15 12.3 0.3 1.7 1 0 0 1 1 1 0 NusB family Methyltransf_3 PF01596.17 OIR57912.1 - 0.084 12.0 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase UBA PF00627.31 OIR57913.1 - 3.9e-12 45.8 0.0 8.4e-10 38.4 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 OIR57913.1 - 1.7e-10 40.5 0.7 3.1e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 OIR57913.1 - 0.0085 16.6 0.2 0.016 15.8 0.2 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rap1_C PF11626.8 OIR57913.1 - 0.0098 16.0 0.0 0.31 11.2 0.0 2.6 2 1 1 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1421 PF07223.11 OIR57913.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Rad60-SLD_2 PF13881.6 OIR57913.1 - 0.031 14.4 0.1 0.068 13.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1296 PF06972.11 OIR57913.1 - 0.033 14.3 0.1 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) Rad60-SLD PF11976.8 OIR57913.1 - 0.077 12.8 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Acetyltransf_1 PF00583.25 OIR57914.1 - 2.1e-11 44.1 0.1 2.5e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OIR57914.1 - 2e-09 37.4 0.0 2.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR57914.1 - 1.9e-07 31.4 0.4 2.7e-07 30.9 0.4 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OIR57914.1 - 5.1e-06 26.4 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 OIR57914.1 - 0.022 14.2 0.1 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase AAA_23 PF13476.6 OIR57915.1 - 4.4e-12 46.9 111.9 0.0097 16.4 92.0 7.0 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OIR57915.1 - 2.6e-08 34.0 0.8 4.8e-05 23.3 0.3 4.1 5 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OIR57915.1 - 1.2e-05 24.9 39.3 0.00024 20.6 39.3 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OIR57915.1 - 4e-05 23.8 0.0 0.00015 21.9 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OIR57915.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 OIR57915.1 - 0.037 12.7 0.0 0.037 12.7 0.0 7.4 5 2 2 8 8 8 0 AAA domain AAA_15 PF13175.6 OIR57915.1 - 0.06 13.0 47.1 0.027 14.2 11.0 5.4 2 2 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 OIR57915.1 - 0.67 10.3 0.0 0.67 10.3 0.0 4.3 4 2 0 5 5 5 0 AAA ATPase domain AAA_22 PF13401.6 OIR57915.1 - 0.74 10.1 4.0 1.9 8.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OIR57915.1 - 8.6 6.9 28.0 0.037 14.5 0.8 6.2 4 2 1 5 5 5 0 ABC transporter Rtt106 PF08512.12 OIR57916.1 - 8.3e-22 77.4 1.1 3e-18 66.0 0.2 3.2 3 0 0 3 3 3 2 Histone chaperone Rttp106-like POB3_N PF17292.2 OIR57916.1 - 5.4e-17 62.0 1.0 7.9e-13 48.7 0.1 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 OIR57916.1 - 2.3e-14 53.0 0.0 7e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) FAM110_C PF14160.6 OIR57916.1 - 0.53 11.4 6.1 5.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus RPN7 PF10602.9 OIR57917.1 - 1.2e-18 67.5 0.3 6.8e-18 65.0 0.1 2.3 3 0 0 3 3 3 1 26S proteasome subunit RPN7 PCI PF01399.27 OIR57917.1 - 3.7e-10 40.3 0.5 8.6e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 PCI domain ubiquitin PF00240.23 OIR57917.1 - 1.3e-09 37.6 0.0 2.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 OIR57917.1 - 0.00056 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 OIR57917.1 - 0.0021 17.8 0.1 0.0041 16.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OIR57917.1 - 0.0027 18.2 0.0 0.0044 17.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CSN8_PSD8_EIF3K PF10075.9 OIR57917.1 - 0.0058 16.6 0.4 0.048 13.6 0.1 2.4 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family CagE_TrbE_VirB PF03135.14 OIR57917.1 - 0.012 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Ribosomal_L21e PF01157.18 OIR57919.1 - 5.9e-38 128.8 0.7 8.7e-38 128.2 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Atg8 PF02991.16 OIR57919.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like RRM_1 PF00076.22 OIR57920.1 - 2.5e-07 30.4 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E3_binding PF02817.17 OIR57920.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain Peptidase_S74 PF13884.6 OIR57920.1 - 1.8 9.0 5.7 1.5e+03 -0.4 5.7 4.6 1 1 0 1 1 1 0 Chaperone of endosialidase Usp PF00582.26 OIR57921.1 - 1.5e-25 90.4 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Taeniidae_ag PF05596.11 OIR57921.1 - 0.014 15.4 0.2 0.024 14.6 0.2 1.3 1 0 0 1 1 1 0 Taeniidae antigen Ribosomal_S4 PF00163.19 OIR57922.1 - 4.5e-06 27.5 0.0 5.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain A2M PF00207.22 OIR57924.1 - 0.011 15.5 0.2 0.04 13.8 0.2 2.1 1 1 0 1 1 1 0 Alpha-2-macroglobulin family Trs65 PF12735.7 OIR57924.1 - 0.032 13.7 0.2 0.044 13.2 0.2 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Ribosomal_S24e PF01282.19 OIR57925.1 - 3.2e-24 84.7 0.4 5.9e-24 83.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e FHA PF00498.26 OIR57926.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain NIBRIN_BRCT_II PF16508.5 OIR57926.1 - 1.1e-05 25.7 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein BRCT PF00533.26 OIR57926.1 - 2.4e-05 24.6 1.6 0.16 12.4 0.1 2.8 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Yop-YscD_cpl PF16697.5 OIR57926.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BRCT_2 PF16589.5 OIR57926.1 - 0.025 15.0 0.1 0.15 12.5 0.0 2.2 2 1 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Csm1 PF12539.8 OIR57927.1 - 6e-11 42.8 0.0 1.3e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF5094 PF17015.5 OIR57927.1 - 8.4e-05 22.7 8.1 0.00063 19.9 0.9 3.1 1 1 1 2 2 2 1 Domain of unknown function (DUF5094) CENP-H PF05837.12 OIR57927.1 - 0.082 13.3 4.6 0.24 11.8 4.6 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 OIR57927.1 - 0.13 12.0 1.9 0.41 10.4 1.9 1.8 1 0 0 1 1 1 0 Septum formation initiator NRBF2 PF08961.10 OIR57927.1 - 0.18 11.4 7.3 0.064 12.9 4.3 1.8 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator ZapB PF06005.12 OIR57927.1 - 0.24 11.9 7.3 0.73 10.3 7.3 1.9 1 0 0 1 1 1 0 Cell division protein ZapB FAM76 PF16046.5 OIR57927.1 - 5.9 6.2 9.1 7.9 5.7 9.1 1.2 1 0 0 1 1 1 0 FAM76 protein DUF3734 PF12536.8 OIR57928.1 - 0.13 12.6 0.2 0.31 11.4 0.2 1.6 1 0 0 1 1 1 0 Patatin phospholipase GAS PF13851.6 OIR57928.1 - 1.6 8.0 7.6 2.8 7.2 7.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CLIP_SPH_mas PF18398.1 OIR57929.1 - 2.1 8.8 4.7 0.59 10.6 1.0 2.0 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade CC2-LZ PF16516.5 OIR57930.1 - 0.31 11.4 7.4 0.066 13.6 1.7 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HIP1_clath_bdg PF16515.5 OIR57930.1 - 0.46 11.1 7.8 1.5 9.4 7.5 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_S27e PF01667.17 OIR57932.1 - 2e-18 65.8 3.2 2.4e-18 65.6 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_12 PF11331.8 OIR57932.1 - 0.0047 16.7 2.6 0.42 10.4 0.0 2.6 2 1 0 2 2 2 2 Probable zinc-ribbon domain Elf1 PF05129.13 OIR57932.1 - 0.005 16.9 0.2 0.0066 16.5 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_6 PF14599.6 OIR57932.1 - 0.037 14.0 0.3 0.059 13.4 0.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon Clat_adaptor_s PF01217.20 OIR57933.1 - 1.4e-32 112.6 0.4 1.5e-32 112.5 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF5623 PF18536.1 OIR57933.1 - 0.013 15.7 0.0 0.017 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) AceK PF06315.11 OIR57933.1 - 0.04 12.4 0.1 0.041 12.4 0.1 1.0 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DUF5091 PF17012.5 OIR57933.1 - 0.055 13.7 0.1 0.46 10.7 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5091) CARDB PF07705.11 OIR57936.1 - 5.1 7.4 8.5 5.7 7.3 3.2 2.3 2 1 0 2 2 2 0 CARDB Spc24 PF08286.11 OIR57937.1 - 1.6e-11 44.3 0.5 7.3e-11 42.2 0.0 2.0 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 YlqD PF11068.8 OIR57937.1 - 0.11 12.9 5.0 0.18 12.2 4.7 1.6 1 1 0 1 1 1 0 YlqD protein Atg14 PF10186.9 OIR57937.1 - 0.64 9.0 2.3 0.88 8.6 2.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pyr_redox_2 PF07992.14 OIR57938.1 - 1.6e-44 152.3 1.8 1.8e-44 152.1 1.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OIR57938.1 - 3.1e-19 69.4 1.7 3.4e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OIR57938.1 - 6.7e-16 58.6 2.0 1.6e-14 54.2 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OIR57938.1 - 5.4e-06 25.8 0.1 0.0042 16.3 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OIR57938.1 - 0.00013 21.5 1.5 0.00063 19.2 0.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OIR57938.1 - 0.00024 21.5 0.1 0.014 15.8 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OIR57938.1 - 0.0026 16.9 5.5 0.28 10.2 0.9 2.8 1 1 1 3 3 3 2 FAD binding domain Thi4 PF01946.17 OIR57938.1 - 0.0039 16.5 0.5 0.02 14.2 0.0 2.3 2 1 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 OIR57938.1 - 0.017 14.5 0.6 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OIR57938.1 - 0.026 13.2 4.1 2.1 7.0 0.0 2.8 3 1 0 3 3 3 0 HI0933-like protein DAO PF01266.24 OIR57938.1 - 0.066 12.8 3.2 1.7 8.2 0.0 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OIR57938.1 - 0.15 12.1 0.1 3.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OIR57938.1 - 1.3 8.0 12.7 2.6 7.0 1.2 3.9 3 1 1 4 4 4 0 Glucose inhibited division protein A Dppa2_A PF14049.6 OIR57939.1 - 0.013 15.6 2.7 0.016 15.3 2.7 1.1 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates GTP_EFTU PF00009.27 OIR57940.1 - 5.7e-51 172.8 0.0 9.5e-51 172.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OIR57940.1 - 1.2e-12 47.7 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OIR57940.1 - 1.7e-05 24.8 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 OIR57940.1 - 0.0081 16.2 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3948 PF13134.6 OIR57941.1 - 0.054 13.2 0.5 0.14 11.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) Hydrolase_4 PF12146.8 OIR57942.1 - 1.3e-14 54.1 0.0 7e-09 35.3 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OIR57942.1 - 5.9e-06 25.9 0.0 1.3e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OIR57942.1 - 8.4e-06 25.6 0.0 0.006 16.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OIR57942.1 - 3.5e-05 24.5 0.1 4.1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.14 OIR57942.1 - 0.00021 21.3 0.0 0.00084 19.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_3 PF07859.13 OIR57942.1 - 0.0004 20.3 0.1 0.26 11.1 0.1 2.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 OIR57942.1 - 0.00061 19.4 0.7 0.28 10.7 0.0 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OIR57942.1 - 0.0052 16.6 0.0 4.4 7.1 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase NTP_transf_3 PF12804.7 OIR57942.1 - 0.0068 16.8 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF5110 PF17137.4 OIR57944.1 - 0.26 11.6 1.9 0.66 10.3 0.3 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5110) Pkinase PF00069.25 OIR57946.1 - 5.5e-47 160.3 1.6 6.4e-47 160.1 1.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57946.1 - 1.3e-20 73.8 0.2 1.3e-19 70.5 0.2 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 OIR57946.1 - 0.036 13.7 2.9 0.32 10.6 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 OIR57947.1 - 8.3e-12 45.0 0.7 9.2e-12 44.9 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR57947.1 - 2.4e-05 23.8 0.2 2.9e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BUD22 PF09073.10 OIR57947.1 - 0.24 10.7 1.7 0.31 10.3 1.7 1.1 1 0 0 1 1 1 0 BUD22 MCRS_N PF13325.6 OIR57950.1 - 0.037 14.0 0.1 0.078 13.0 0.1 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DUF3060 PF11259.8 OIR57951.1 - 7.8e-22 76.7 36.7 0.00017 21.2 0.8 7.5 4 1 2 7 7 7 7 Protein of unknown function (DUF3060) Cu_amine_oxidN1 PF07833.11 OIR57951.1 - 0.75 10.3 6.4 25 5.5 0.3 3.7 2 1 0 2 2 2 0 Copper amine oxidase N-terminal domain PCC_BT PF18140.1 OIR57951.1 - 1.4 9.3 6.1 3.4 8.0 0.2 3.3 2 2 1 3 3 3 0 Propionyl-coenzyme A carboxylase BT domain WD40 PF00400.32 OIR57952.1 - 3.4e-21 75.1 6.0 1.7e-05 25.5 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR57952.1 - 1.2e-13 51.1 0.0 2.5e-08 34.1 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OIR57952.1 - 1.2e-06 28.1 0.0 1.7e-05 24.4 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 OIR57952.1 - 0.087 11.8 0.1 6.4 5.6 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 OIR57952.1 - 0.12 12.2 0.3 0.29 10.9 0.3 1.8 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.11 OIR57952.1 - 0.12 12.2 0.1 2.7 7.8 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A NAD_Gly3P_dh_N PF01210.23 OIR57953.1 - 2.1e-42 144.8 0.0 4.9e-42 143.6 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 OIR57953.1 - 8.1e-26 91.0 0.0 1.3e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 OIR57953.1 - 0.00033 21.2 1.2 0.0052 17.3 0.4 2.9 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 OIR57953.1 - 0.0022 17.4 0.1 0.004 16.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 OIR57953.1 - 0.015 15.7 0.1 0.22 12.0 0.1 2.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OIR57953.1 - 0.025 14.4 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 OIR57953.1 - 0.027 14.1 0.2 0.062 13.0 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OIR57953.1 - 0.036 14.3 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain IlvN PF07991.12 OIR57953.1 - 0.037 13.6 0.2 3.6 7.1 0.0 2.4 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glyco_hydro_4 PF02056.16 OIR57953.1 - 0.076 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase DUF4466 PF14725.6 OIR57953.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) UPF0086 PF01868.16 OIR57954.1 - 5.7e-19 67.8 0.1 8.5e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Synaptobrevin PF00957.21 OIR57956.1 - 2.4e-12 46.4 0.3 4.5e-12 45.6 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OIR57956.1 - 3e-10 40.0 0.0 6.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Syntaxin-6_N PF09177.11 OIR57956.1 - 0.029 14.9 0.5 0.054 14.0 0.5 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SpoIIE PF07228.12 OIR57957.1 - 4.1e-06 26.8 0.1 1.5e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OIR57957.1 - 0.0071 16.0 0.0 0.031 13.9 0.0 2.2 2 1 0 2 2 2 1 Protein phosphatase 2C Ras PF00071.22 OIR57958.1 - 8.2e-59 197.8 0.4 1e-58 197.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR57958.1 - 1.2e-35 122.3 0.3 1.8e-35 121.7 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR57958.1 - 1.3e-13 50.7 0.1 1.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OIR57958.1 - 3.4e-06 27.1 0.1 4.9e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OIR57958.1 - 0.00018 21.0 0.1 0.00025 20.5 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OIR57958.1 - 0.003 17.5 0.1 0.073 13.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 OIR57958.1 - 0.007 15.7 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 OIR57958.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 OIR57958.1 - 0.018 15.5 0.3 0.032 14.6 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OIR57958.1 - 0.02 14.4 0.3 0.12 12.0 0.2 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OIR57958.1 - 0.025 14.9 0.1 0.087 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OIR57958.1 - 0.052 13.3 0.1 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 OIR57958.1 - 0.056 12.7 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Septin Pox_A32 PF04665.12 OIR57958.1 - 0.057 12.9 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein FeoB_N PF02421.18 OIR57958.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 OIR57958.1 - 0.13 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 OIR57958.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 OIR57958.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain zf-RING_2 PF13639.6 OIR57960.1 - 2.1e-12 47.1 4.5 2.2e-12 47.1 2.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OIR57960.1 - 1.7e-10 40.6 5.2 2.3e-10 40.1 3.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OIR57960.1 - 3e-07 30.6 11.7 2.3e-06 27.8 11.8 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OIR57960.1 - 6.1e-07 29.1 0.5 1.2e-06 28.1 0.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 OIR57960.1 - 6.5e-07 29.3 3.0 6.5e-07 29.3 3.0 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OIR57960.1 - 1.1e-05 25.2 9.3 2.6e-05 24.0 6.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR57960.1 - 2.9e-05 23.9 1.9 2.9e-05 23.9 1.9 2.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OIR57960.1 - 0.00064 19.7 6.2 0.0011 19.0 6.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OIR57960.1 - 0.016 15.0 6.4 0.016 15.0 6.4 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OIR57960.1 - 0.017 15.1 2.8 0.017 15.1 2.8 2.5 2 1 0 2 2 2 0 Zinc-finger Zn_ribbon_17 PF17120.5 OIR57960.1 - 0.025 14.2 8.0 0.06 13.0 8.0 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 OIR57960.1 - 0.047 13.5 5.5 0.19 11.6 2.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 OIR57960.1 - 0.051 13.7 1.5 0.051 13.7 1.5 2.0 2 1 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 OIR57960.1 - 0.066 13.4 4.7 0.16 12.2 4.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 OIR57960.1 - 0.074 13.2 5.2 0.19 11.9 4.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OIR57960.1 - 0.21 11.9 7.6 0.97 9.8 7.6 2.1 1 1 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 OIR57960.1 - 2.1 8.3 12.6 17 5.4 10.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Sin3a_C PF16879.5 OIR57961.1 - 1.1e-16 61.5 0.1 6.4e-16 58.9 0.1 2.3 1 1 0 1 1 1 1 C-terminal domain of Sin3a protein DUF2407 PF10302.9 OIR57962.1 - 0.03 14.9 0.1 0.049 14.2 0.1 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-CCCH PF00642.24 OIR57963.1 - 7.4e-21 73.6 28.0 2.9e-06 27.0 1.2 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OIR57963.1 - 1.5e-19 69.4 40.1 3.1e-06 27.1 2.3 6.0 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 OIR57963.1 - 2e-19 70.3 23.4 2.7e-05 24.8 0.7 5.3 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OIR57963.1 - 2.8e-09 36.6 31.9 1.5e-05 24.7 0.5 5.0 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCHC PF00098.23 OIR57963.1 - 4.4e-06 26.5 1.8 4.4e-06 26.5 1.8 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_3 PF15663.5 OIR57963.1 - 1.7e-05 25.0 25.2 0.29 11.4 2.5 4.7 1 1 2 3 3 3 3 Zinc-finger containing family eIF3g PF12353.8 OIR57963.1 - 0.0071 16.7 2.2 0.0071 16.7 2.2 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 OIR57963.1 - 0.13 12.0 0.6 0.13 12.0 0.6 2.5 3 1 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCCH_2 PF14608.6 OIR57963.1 - 0.29 11.7 38.6 0.15 12.6 2.1 6.2 7 1 0 7 7 7 0 RNA-binding, Nab2-type zinc finger AfsA PF03756.13 OIR57964.1 - 0.042 13.8 2.1 0.067 13.2 1.4 1.7 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain Peptidase_M24 PF00557.24 OIR57967.1 - 1.4e-14 54.3 0.1 1.7e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF563 PF04577.14 OIR57968.1 - 1.2e-18 68.0 0.1 2.2e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) O-FucT PF10250.9 OIR57968.1 - 4.3e-17 62.8 0.2 2.6e-12 47.1 0.3 2.5 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_transf_20 PF00982.21 OIR57969.1 - 1.2e-165 551.8 0.0 1.4e-165 551.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OIR57969.1 - 4.2e-08 32.6 0.0 3.4e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 OIR57969.1 - 0.15 11.6 0.1 10 5.6 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferases group 1 GTP_EFTU PF00009.27 OIR57970.1 - 5.3e-34 117.5 0.1 2.2e-33 115.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OIR57970.1 - 1.2e-17 63.9 0.0 3.2e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OIR57970.1 - 2.6e-13 50.1 5.4 1.1e-06 28.9 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 OIR57970.1 - 5.1e-13 48.7 0.6 1.2e-12 47.5 0.6 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 OIR57970.1 - 1.1e-07 31.9 0.0 5.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OIR57970.1 - 0.0028 17.5 0.0 0.0055 16.5 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Roc PF08477.13 OIR57970.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gcd10p PF04189.13 OIR57971.1 - 1.4e-16 60.5 0.1 1.9e-13 50.2 0.0 2.1 1 1 1 2 2 2 2 Gcd10p family BESS PF02944.20 OIR57971.1 - 0.17 11.7 0.2 0.33 10.8 0.2 1.5 1 0 0 1 1 1 0 BESS motif ECR1_N PF14382.6 OIR57973.1 - 1.4e-11 44.0 0.0 9.3e-11 41.3 0.0 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 OIR57973.1 - 5.9e-05 23.3 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 OIR57973.1 - 0.0026 18.4 0.1 0.006 17.2 0.1 1.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 PCB_OB PF17092.5 OIR57973.1 - 0.0066 17.2 0.1 0.025 15.3 0.2 1.7 1 1 1 2 2 2 1 Penicillin-binding protein OB-like domain UCH PF00443.29 OIR57974.1 - 5.3e-20 72.0 0.7 4.4e-18 65.7 0.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR57974.1 - 0.00014 21.6 0.2 0.0075 15.9 0.0 2.5 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4834 PF16118.5 OIR57974.1 - 0.0048 17.8 0.2 0.015 16.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Plasmodium_Vir PF05795.11 OIR57974.1 - 0.005 16.3 1.1 0.0075 15.7 1.1 1.3 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Vpu PF00558.19 OIR57974.1 - 0.043 13.6 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Vpu protein SpoIIIAH PF12685.7 OIR57974.1 - 0.045 13.6 5.0 0.065 13.1 4.9 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein Mucin PF01456.17 OIR57974.1 - 0.069 13.1 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.17 OIR57974.1 - 0.47 9.2 1.0 0.55 8.9 1.0 1.2 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 OIR57974.1 - 3.1 8.2 6.6 66 3.8 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF2197 PF09963.9 OIR57975.1 - 0.078 13.2 2.0 0.22 11.8 2.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C3HC4_5 PF17121.5 OIR57975.1 - 0.17 11.8 2.2 0.39 10.6 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OIR57976.1 - 0.0012 18.6 6.0 0.0012 18.6 6.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) QSOX_Trx1 PF18108.1 OIR57976.1 - 0.046 13.9 0.2 2.5 8.3 0.0 3.2 2 1 1 3 3 3 0 QSOX Trx-like domain zf-UDP PF14569.6 OIR57976.1 - 0.047 13.8 3.4 0.11 12.6 3.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger TPR_19 PF14559.6 OIR57977.1 - 4.1e-14 52.8 9.5 0.00041 20.8 0.0 6.9 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OIR57977.1 - 3.9e-06 27.1 23.6 0.028 14.7 0.2 7.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR57977.1 - 8.2e-05 23.2 7.9 0.7 10.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR57977.1 - 0.00012 22.2 11.9 0.013 15.7 0.8 4.1 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OIR57977.1 - 0.00062 20.0 0.1 0.14 12.6 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OIR57977.1 - 0.0011 19.4 11.2 67 4.4 0.0 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat NARP1 PF12569.8 OIR57977.1 - 0.0055 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 OIR57977.1 - 0.0063 16.8 0.1 0.56 10.6 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OIR57977.1 - 0.014 14.6 0.3 14 4.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OIR57977.1 - 0.015 15.5 16.4 4.3 7.8 0.1 8.8 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.6 OIR57977.1 - 0.03 14.3 10.9 6.2 7.1 0.0 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OIR57977.1 - 0.051 14.4 12.9 32 5.7 0.1 7.3 7 2 2 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OIR57977.1 - 0.058 13.3 12.3 1.6 8.7 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OIR57977.1 - 0.1 12.8 24.2 0.69 10.2 0.0 9.5 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_10 PF13374.6 OIR57977.1 - 3.1 7.8 14.3 34 4.5 0.1 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.8 OIR57978.1 - 0.0017 18.6 3.4 0.0025 18.0 3.4 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding GAS PF13851.6 OIR57978.1 - 0.0031 16.9 4.7 0.004 16.5 4.7 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 OIR57978.1 - 0.0038 17.3 5.3 0.64 10.2 0.2 2.4 1 1 1 2 2 2 2 bZIP transcription factor Tropomyosin_1 PF12718.7 OIR57978.1 - 0.035 14.3 7.1 0.05 13.8 7.1 1.4 1 0 0 1 1 1 0 Tropomyosin like Gp-FAR-1 PF05823.12 OIR57978.1 - 0.043 14.2 0.6 0.061 13.7 0.6 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) bZIP_2 PF07716.15 OIR57978.1 - 0.046 13.8 9.1 0.52 10.4 1.3 2.9 2 1 0 2 2 2 0 Basic region leucine zipper TMCO5 PF14992.6 OIR57978.1 - 0.055 13.0 7.0 0.44 10.1 0.4 2.0 1 1 1 2 2 2 0 TMCO5 family Myb_DNA-bind_4 PF13837.6 OIR57978.1 - 0.056 13.8 1.4 4.4 7.7 0.4 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Troponin PF00992.20 OIR57978.1 - 0.11 12.8 7.5 0.21 11.9 7.5 1.6 1 1 0 1 1 1 0 Troponin WDCP PF15390.6 OIR57978.1 - 0.19 10.1 1.3 0.22 9.9 1.3 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family V_ATPase_I PF01496.19 OIR57978.1 - 0.21 9.5 1.3 0.25 9.2 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 OIR57978.1 - 0.21 10.1 1.3 0.25 9.8 1.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ax_dynein_light PF10211.9 OIR57978.1 - 0.3 11.0 6.2 3.8 7.4 6.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain GrpE PF01025.19 OIR57978.1 - 0.45 10.2 6.6 0.22 11.2 1.2 2.4 1 1 2 3 3 3 0 GrpE Phage_GPO PF05929.11 OIR57978.1 - 0.49 10.0 3.2 0.6 9.7 2.4 1.5 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SlyX PF04102.12 OIR57978.1 - 3 8.5 5.7 18 6.1 4.9 2.3 1 1 1 2 2 2 0 SlyX HEAT_2 PF13646.6 OIR57979.1 - 5.5e-05 23.5 4.0 0.027 14.9 0.0 5.0 4 1 0 5 5 5 1 HEAT repeats DUF3361 PF11841.8 OIR57979.1 - 0.0004 20.4 14.0 1.1 9.1 0.6 5.0 3 2 2 5 5 5 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 OIR57979.1 - 0.0035 17.5 11.1 0.66 10.1 2.5 4.2 3 1 1 4 4 4 2 V-ATPase subunit H HEAT PF02985.22 OIR57979.1 - 0.0078 16.4 0.0 0.36 11.2 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat Xpo1 PF08389.12 OIR57979.1 - 0.015 15.4 1.1 0.37 10.8 0.3 3.3 2 1 1 3 3 3 0 Exportin 1-like protein Cnd1 PF12717.7 OIR57979.1 - 0.026 14.6 8.0 0.88 9.6 2.1 3.5 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 OIR57979.1 - 0.06 13.4 6.3 0.075 13.1 0.1 3.8 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain DZF PF07528.14 OIR57979.1 - 0.11 12.1 0.2 0.11 12.1 0.2 2.8 2 1 0 3 3 3 0 DZF domain DUF5578 PF17741.1 OIR57979.1 - 0.17 11.2 8.8 1.4 8.3 0.5 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5578) DED PF01335.21 OIR57979.1 - 1.2 9.5 5.9 0.53 10.6 0.6 3.2 3 0 0 3 3 3 0 Death effector domain UQ_con PF00179.26 OIR57980.1 - 2.2e-46 157.0 0.0 2.5e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR57980.1 - 0.0028 17.4 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B SNF2_N PF00176.23 OIR57981.1 - 1.3e-62 211.6 1.2 1.3e-62 211.6 1.2 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OIR57981.1 - 2.7e-18 66.3 0.0 1e-17 64.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLIDE PF09111.10 OIR57981.1 - 2.7e-10 40.2 6.9 3e-10 40.1 2.3 2.8 1 1 1 2 2 2 1 SLIDE ResIII PF04851.15 OIR57981.1 - 1.6e-08 34.7 1.0 3.4e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OIR57981.1 - 9.1e-06 25.0 0.0 4.6e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 HAND PF09110.11 OIR57981.1 - 8.8e-05 23.2 6.4 8.8e-05 23.2 6.4 2.7 2 0 0 2 2 2 1 HAND ERCC3_RAD25_C PF16203.5 OIR57981.1 - 0.0073 15.6 0.1 0.02 14.1 0.1 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PTPA PF03095.15 OIR57982.1 - 1.8e-54 185.2 0.0 3.4e-54 184.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein EMP24_GP25L PF01105.24 OIR57983.1 - 1.4e-25 90.3 0.0 1.6e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DMPK_coil PF08826.10 OIR57983.1 - 0.089 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 DMPK coiled coil domain like Noelin-1 PF12308.8 OIR57983.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein Zn_clus PF00172.18 OIR57984.1 - 0.00015 21.8 16.2 0.00025 21.1 16.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spindle_Spc25 PF08234.12 OIR57985.1 - 2.8e-12 46.7 0.0 4.1e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Borrelia_P83 PF05262.11 OIR57985.1 - 0.13 10.7 2.2 0.16 10.4 2.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FUSC PF04632.12 OIR57985.1 - 0.34 9.4 0.6 0.4 9.2 0.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family V-ATPase_C PF03223.15 OIR57986.1 - 1.3e-47 163.0 0.0 1.7e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C CAS_CSE1 PF03378.15 OIR57987.1 - 0.023 13.2 0.0 0.075 11.5 0.0 1.8 1 1 1 2 2 2 0 CAS/CSE protein, C-terminus Ost5 PF05251.12 OIR57987.1 - 0.041 14.1 0.3 1.6 9.1 0.0 2.5 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 zf-C2H2 PF00096.26 OIR57988.1 - 4.2e-11 42.7 36.4 0.00018 21.8 0.5 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OIR57988.1 - 4e-10 39.6 36.8 0.0051 17.6 1.9 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OIR57988.1 - 0.011 16.2 34.1 1.1 9.8 0.1 6.8 7 0 0 7 7 7 0 Zinc-finger double domain zf-Di19 PF05605.12 OIR57988.1 - 0.029 14.7 2.1 0.029 14.7 2.1 4.4 3 2 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TRAF6_Z2 PF18048.1 OIR57988.1 - 0.096 12.8 0.2 0.096 12.8 0.2 3.6 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_jaz PF12171.8 OIR57988.1 - 0.66 10.3 0.1 0.66 10.3 0.1 4.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OIR57988.1 - 1.8 8.4 30.1 0.38 10.6 2.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.7 OIR57988.1 - 3.8 8.0 13.0 1.4 9.4 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Sad1_UNC PF07738.13 OIR57989.1 - 7.2e-26 90.8 0.0 2.1e-25 89.3 0.0 1.8 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Nup54 PF13874.6 OIR57989.1 - 0.0069 16.5 3.4 0.015 15.4 3.4 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 UPF0242 PF06785.11 OIR57989.1 - 0.0082 16.3 5.7 0.0082 16.3 5.7 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 OIR57989.1 - 0.014 14.7 2.6 0.014 14.7 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 OIR57989.1 - 1.3 9.5 11.3 0.51 10.9 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 OIR57989.1 - 4.3 7.8 26.4 0.17 12.3 13.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 OIR57989.1 - 6.6 5.9 12.9 3.6 6.7 10.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein Histone PF00125.24 OIR57990.1 - 3.2e-41 140.8 0.0 3.7e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OIR57990.1 - 0.0021 18.4 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OIR57990.1 - 0.0025 17.9 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 OIR57990.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 OIR57991.1 - 5.7e-15 54.9 0.0 7.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OIR57991.1 - 0.00022 21.7 1.6 0.00047 20.7 1.6 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Limkain-b1 PF11608.8 OIR57991.1 - 0.024 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 OIR57991.1 - 0.043 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 OIR57992.1 - 8.3e-15 54.9 0.9 0.00014 22.6 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 OIR57992.1 - 3.8e-05 23.2 0.0 0.00039 19.8 0.0 2.3 1 1 2 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 OIR57992.1 - 0.0036 17.3 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Apolipoprotein PF01442.18 OIR57993.1 - 0.0028 17.6 3.8 0.0038 17.1 3.8 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 OIR57993.1 - 0.057 13.3 3.9 0.099 12.5 3.9 1.4 1 0 0 1 1 1 0 PIN like domain Spore_III_AB PF09548.10 OIR57993.1 - 0.061 13.4 1.4 0.09 12.9 1.4 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) OmpH PF03938.14 OIR57993.1 - 0.29 11.5 3.4 0.61 10.4 2.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FbpA PF05833.11 OIR57994.1 - 2.7e-30 105.6 0.0 2.4e-29 102.4 0.0 2.0 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 OIR57994.1 - 6.3e-23 81.5 0.0 1.1e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 OIR57994.1 - 4.2e-20 71.6 0.0 1.6e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 NFACT protein C-terminal domain Phasin PF05597.11 OIR57994.1 - 0.11 12.5 3.9 2.5 8.1 0.4 2.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) THOC7 PF05615.13 OIR57994.1 - 3 8.1 14.0 0.29 11.4 1.2 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 Exonuc_VII_L PF02601.15 OIR57994.1 - 7.2 6.1 8.3 25 4.3 8.4 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Cohesin_load PF10345.9 OIR57995.1 - 0.0043 15.6 5.2 0.021 13.3 0.4 2.2 2 0 0 2 2 2 2 Cohesin loading factor ELYS PF13934.6 OIR57995.1 - 0.062 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Nuclear pore complex assembly PI3_PI4_kinase PF00454.27 OIR57996.1 - 1.8e-47 162.3 0.0 4.8e-47 160.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OIR57996.1 - 8.2e-10 38.3 0.0 2.4e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 FATC domain Sec1 PF00995.23 OIR57997.1 - 6.4e-76 256.8 0.0 5.5e-75 253.7 0.0 1.9 1 1 0 1 1 1 1 Sec1 family DUF1825 PF08855.10 OIR57997.1 - 0.024 14.6 0.1 0.059 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Myosin_head PF00063.21 OIR57998.1 - 8.1e-151 503.5 0.0 7.7e-150 500.3 0.0 2.3 1 1 1 2 2 2 1 Myosin head (motor domain) AAA_16 PF13191.6 OIR57998.1 - 1.5e-05 25.4 0.8 0.00021 21.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain DIL PF01843.19 OIR57998.1 - 0.00025 21.3 0.3 0.00075 19.7 0.3 1.8 1 0 0 1 1 1 1 DIL domain AAA_22 PF13401.6 OIR57998.1 - 0.0086 16.3 0.8 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OIR57998.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.9 OIR57998.1 - 0.018 14.3 1.1 0.027 13.7 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PKcGMP_CC PF16808.5 OIR57998.1 - 0.049 13.5 4.6 0.13 12.1 4.6 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NACHT PF05729.12 OIR57998.1 - 0.067 13.1 0.0 0.33 10.9 0.0 2.2 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 OIR57998.1 - 0.11 12.6 0.7 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 OIR57998.1 - 0.13 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OIR57998.1 - 0.15 12.6 0.6 1 9.9 0.1 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 OIR57998.1 - 0.19 12.2 6.4 3.9 7.9 0.3 2.9 3 0 0 3 3 2 0 AAA domain Ribosomal_L23 PF00276.20 OIR57999.1 - 1.9e-10 41.0 1.0 1.9e-10 41.0 1.0 2.9 2 1 0 2 2 2 1 Ribosomal protein L23 CLTH PF10607.9 OIR58000.1 - 1.5e-23 83.3 1.7 3.2e-23 82.3 1.7 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Msap1 PF17077.5 OIR58000.1 - 0.019 14.2 0.3 0.027 13.7 0.3 1.2 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 Fez1 PF06818.15 OIR58000.1 - 0.16 12.4 7.4 0.27 11.7 7.4 1.3 1 0 0 1 1 1 0 Fez1 Cdh1_DBD_1 PF18196.1 OIR58000.1 - 1.1 9.5 8.0 0.63 10.4 2.0 2.5 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 zf-RING_2 PF13639.6 OIR58000.1 - 6.3 7.2 9.0 2.7 8.4 2.1 2.8 2 0 0 2 2 2 0 Ring finger domain Nuf2 PF03800.14 OIR58001.1 - 7.5e-37 126.6 0.0 2.1e-36 125.1 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family Cep57_MT_bd PF06657.13 OIR58001.1 - 0.0029 18.0 7.5 0.0029 18.0 7.5 4.5 3 3 1 5 5 5 1 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 OIR58001.1 - 2.2 8.4 54.5 0.061 13.4 2.6 4.1 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein DEAD PF00270.29 OIR58002.1 - 1.5e-40 138.8 0.1 2.4e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58002.1 - 2.3e-21 76.2 0.0 9.1e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OIR58002.1 - 5.7e-14 52.1 0.2 1.4e-13 50.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OIR58002.1 - 0.0032 17.5 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OIR58002.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 OIR58002.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain La PF05383.17 OIR58003.1 - 1.2e-19 70.1 0.2 5.6e-19 68.0 0.0 2.1 1 1 1 2 2 2 1 La domain RRM_1 PF00076.22 OIR58003.1 - 0.022 14.6 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP_N PF05195.16 OIR58003.1 - 0.045 13.5 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain PAS_2 PF08446.11 OIR58003.1 - 0.13 12.9 0.1 1.4 9.6 0.0 2.3 2 1 0 2 2 2 0 PAS fold Holin_BhlA PF10960.8 OIR58003.1 - 0.37 10.8 2.1 0.98 9.4 2.1 1.7 1 0 0 1 1 1 0 BhlA holin family ERO1 PF04137.15 OIR58004.1 - 4.1e-56 190.7 8.1 1.8e-55 188.6 8.1 1.9 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Telomerase_RBD PF12009.8 OIR58005.1 - 7.5e-23 81.1 0.1 1.9e-22 79.8 0.1 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OIR58005.1 - 4.4e-13 49.2 0.1 3.9e-09 36.4 0.0 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.25 OIR58006.1 - 4.1e-62 209.9 0.0 4.8e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58006.1 - 5.6e-31 107.8 0.0 6.9e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR58006.1 - 0.00011 22.2 0.1 0.0014 18.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR58006.1 - 0.0012 18.2 0.0 0.0047 16.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OIR58006.1 - 0.002 17.8 0.1 0.005 16.5 0.0 1.6 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Methyltr_RsmB-F PF01189.17 OIR58007.1 - 5.5e-61 205.7 0.0 8.9e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OIR58007.1 - 3.6e-05 24.0 0.1 7.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmF_N PF17125.5 OIR58007.1 - 0.00053 20.4 0.1 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 OIR58007.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Fibrillarin PF01269.17 OIR58007.1 - 0.0094 15.1 0.1 0.031 13.4 0.0 1.8 2 0 0 2 2 2 1 Fibrillarin NLRC4_HD2 PF17776.1 OIR58008.1 - 0.12 12.9 0.2 1.7 9.2 0.1 2.5 2 1 1 3 3 3 0 NLRC4 helical domain HD2 DUF5607 PF18355.1 OIR58008.1 - 0.12 12.8 0.2 0.96 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5607) DUF1940 PF09155.10 OIR58009.1 - 0.0053 16.9 0.7 0.0063 16.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1940) TEBP_beta PF07404.11 OIR58009.1 - 0.0088 15.4 0.5 0.01 15.2 0.5 1.1 1 0 0 1 1 1 1 Telomere-binding protein beta subunit (TEBP beta) eIF-4B PF06273.11 OIR58009.1 - 0.025 13.6 2.4 0.028 13.5 2.4 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B eRF1_1 PF03463.15 OIR58009.1 - 0.031 14.3 0.7 0.037 14.0 0.7 1.2 1 0 0 1 1 1 0 eRF1 domain 1 DNA_pol_B_exo1 PF03104.19 OIR58010.1 - 2e-57 194.8 0.0 4.3e-57 193.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 OIR58010.1 - 3.8e-30 104.7 1.5 6.1e-14 51.4 0.0 4.0 3 1 0 3 3 3 2 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 OIR58010.1 - 3e-12 46.0 0.9 1e-06 27.8 0.1 3.6 3 1 0 3 3 3 2 DNA polymerase family B RNase_H_2 PF13482.6 OIR58010.1 - 9.6e-07 28.9 0.1 5.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 OIR58010.1 - 3.5e-06 26.9 0.0 8.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB TerY_C PF15616.6 OIR58010.1 - 0.067 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 TerY-C metal binding domain DHHC PF01529.20 OIR58011.1 - 3.4e-19 69.3 20.1 3.4e-19 69.3 20.1 3.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4149 PF13664.6 OIR58011.1 - 5.8 7.3 8.4 0.2 12.0 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) FHA PF00498.26 OIR58012.1 - 6.7e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OIR58012.1 - 1.3e-05 25.5 0.0 3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF445 PF04286.12 OIR58012.1 - 0.12 12.2 28.8 0.18 11.6 28.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) MT0933_antitox PF14013.6 OIR58012.1 - 0.73 10.2 47.1 5.9 7.3 6.1 6.3 1 1 3 4 4 4 0 MT0933-like antitoxin protein Cornifin PF02389.15 OIR58012.1 - 5 7.3 29.6 12 6.1 14.1 2.6 1 1 1 2 2 2 0 Cornifin (SPRR) family RHD3 PF05879.12 OIR58012.1 - 7.5 4.6 33.2 11 4.0 33.2 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) ERO1 PF04137.15 OIR58013.1 - 7.7e-50 170.1 7.8 3.5e-47 161.3 7.8 2.8 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HupH_C PF04809.13 OIR58013.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Med10 PF09748.9 OIR58013.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex RRP36 PF06102.12 OIR58014.1 - 7.5e-26 91.1 20.6 9.4e-26 90.7 20.6 1.0 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 SPT16 PF08644.11 OIR58014.1 - 2.1 8.5 17.5 17 5.5 17.5 2.0 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Proteasome PF00227.26 OIR58015.1 - 1.3e-46 158.5 0.1 1.5e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit PYC_OADA PF02436.18 OIR58016.1 - 0.0046 16.7 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 2 Conserved carboxylase domain DUF3549 PF12069.8 OIR58016.1 - 0.013 14.6 0.4 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) CDP-OH_P_transf PF01066.21 OIR58020.1 - 1.1e-13 51.7 0.3 1.1e-13 51.7 0.3 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sec20 PF03908.13 OIR58021.1 - 6.2e-15 54.9 0.8 7.2e-15 54.7 0.8 1.1 1 0 0 1 1 1 1 Sec20 LTV PF04180.14 OIR58022.1 - 2.9 7.5 8.5 8.1 6.1 8.0 1.7 1 1 1 2 2 2 0 Low temperature viability protein WD40 PF00400.32 OIR58023.1 - 3.6e-23 81.4 11.6 6.2e-05 23.7 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58023.1 - 2e-07 31.2 0.0 0.5 10.7 0.0 5.2 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OIR58023.1 - 0.0011 18.9 0.0 0.023 14.6 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OIR58023.1 - 0.0019 18.1 1.2 3.8 7.6 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OIR58023.1 - 0.1 11.5 0.1 15 4.4 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_67N PF03648.14 OIR58024.1 - 0.014 15.7 0.4 0.02 15.2 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus Arf PF00025.21 OIR58025.1 - 1.8e-47 161.1 0.0 2e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OIR58025.1 - 2e-09 37.1 0.5 1.2e-05 24.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OIR58025.1 - 1.2e-08 35.2 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OIR58025.1 - 1.7e-06 28.1 0.0 4.3e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 OIR58025.1 - 4.3e-05 23.2 0.0 5.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OIR58025.1 - 8.6e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OIR58025.1 - 0.00021 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OIR58025.1 - 0.0077 15.8 0.0 0.85 9.1 0.0 2.2 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 OIR58025.1 - 0.08 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 TIR domain NACHT PF05729.12 OIR58025.1 - 0.081 12.8 0.1 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain PCI PF01399.27 OIR58026.1 - 2e-07 31.5 0.0 1.1e-06 29.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain Pkinase PF00069.25 OIR58027.1 - 7.2e-55 186.2 0.0 8.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58027.1 - 3.5e-18 65.8 0.1 7.2e-18 64.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OIR58027.1 - 3.2e-10 40.3 0.1 5.7e-07 29.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OIR58027.1 - 0.0044 16.4 0.1 0.0092 15.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OIR58027.1 - 0.0058 15.5 0.6 0.017 13.9 0.1 1.8 1 1 1 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 OIR58027.1 - 0.0095 15.5 0.5 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 OIR58027.1 - 0.11 11.9 0.4 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase DBP10CT PF08147.12 OIR58028.1 - 0.43 10.9 3.0 0.8 10.0 3.0 1.5 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Vac_ImportDeg PF09783.9 OIR58029.1 - 8.9e-34 116.6 0.0 1.1e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF3482 PF11981.8 OIR58031.1 - 0.12 11.8 0.3 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Swi5 PF07061.11 OIR58032.1 - 8.1e-18 64.3 0.7 1.2e-17 63.7 0.7 1.4 1 0 0 1 1 1 1 Swi5 DUF2096 PF09869.9 OIR58032.1 - 0.014 15.5 0.5 0.033 14.3 0.3 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) APG6_N PF17675.1 OIR58032.1 - 2.3 8.7 8.8 3.7 8.1 8.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region tRNA-synt_1d PF00750.19 OIR58034.1 - 3.2e-94 315.7 2.0 4.6e-94 315.2 2.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OIR58034.1 - 4.8e-20 71.9 0.0 1.5e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 OIR58034.1 - 8.2e-05 23.1 0.0 0.00029 21.4 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Endonuc-MspI PF09208.10 OIR58034.1 - 0.033 13.6 0.1 0.11 11.8 0.1 1.8 1 1 0 1 1 1 0 Restriction endonuclease MspI Sec10 PF07393.11 OIR58035.1 - 1.1e-36 126.5 0.0 1.4e-26 93.2 0.0 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec10 HTH_Tnp_Tc3_2 PF01498.18 OIR58035.1 - 0.058 13.6 1.1 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 Transposase Toxin_5 PF05294.13 OIR58035.1 - 1.3 9.5 5.6 0.81 10.2 3.1 1.9 2 0 0 2 2 2 0 Scorpion short toxin FANCI_S1 PF14675.6 OIR58036.1 - 1.7e-08 34.3 0.1 4.2e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 FANCI solenoid 1 Pox_A8 PF04745.12 OIR58036.1 - 0.21 10.6 1.9 0.18 10.9 0.3 1.6 2 0 0 2 2 2 0 VITF-3 subunit protein WD40 PF00400.32 OIR58037.1 - 6.5e-14 52.1 14.5 5.8e-05 23.8 0.3 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PFU PF09070.11 OIR58037.1 - 1.4e-10 41.4 0.0 1.2e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 OIR58037.1 - 1.4e-08 34.3 0.6 2.3e-08 33.6 0.6 1.3 1 0 0 1 1 1 1 PUL domain PQQ_3 PF13570.6 OIR58037.1 - 0.47 11.0 6.0 65 4.2 0.0 4.9 5 0 0 5 5 5 0 PQQ-like domain AAA PF00004.29 OIR58038.1 - 1e-49 168.4 0.1 3.7e-40 137.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OIR58038.1 - 1.5e-08 35.0 1.8 0.0016 18.7 0.3 4.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 OIR58038.1 - 2e-08 34.8 0.1 0.0047 17.3 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 OIR58038.1 - 2.4e-07 30.8 0.1 0.00016 21.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 OIR58038.1 - 6.3e-07 29.1 0.1 4.7e-06 26.3 0.2 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 OIR58038.1 - 7e-07 29.5 0.0 7e-06 26.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) TsaE PF02367.17 OIR58038.1 - 1.6e-05 24.9 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 OIR58038.1 - 2.1e-05 24.3 0.2 0.15 11.8 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OIR58038.1 - 3e-05 23.5 0.1 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OIR58038.1 - 3.5e-05 24.1 0.0 0.042 14.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 OIR58038.1 - 9.1e-05 22.0 0.2 0.039 13.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 OIR58038.1 - 0.00012 21.8 0.0 0.13 12.0 0.0 2.7 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 OIR58038.1 - 0.00014 22.1 0.0 0.041 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OIR58038.1 - 0.00024 21.6 0.8 0.0068 16.9 0.1 2.7 3 0 0 3 3 2 1 ABC transporter NACHT PF05729.12 OIR58038.1 - 0.00035 20.5 1.2 0.18 11.7 0.1 2.8 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 OIR58038.1 - 0.00035 20.6 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OIR58038.1 - 0.00046 20.7 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OIR58038.1 - 0.00048 19.9 0.0 0.037 13.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 OIR58038.1 - 0.0007 18.9 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain CDC48_2 PF02933.17 OIR58038.1 - 0.00071 19.3 2.9 0.0021 17.8 0.5 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 NB-ARC PF00931.22 OIR58038.1 - 0.00086 18.6 0.1 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 OIR58038.1 - 0.0025 17.4 1.1 2.3 7.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 OIR58038.1 - 0.0046 16.9 0.2 5.3 6.9 0.0 3.4 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 OIR58038.1 - 0.0053 16.5 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 OIR58038.1 - 0.0067 16.2 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OIR58038.1 - 0.0068 15.8 0.0 0.41 10.0 0.0 2.5 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 OIR58038.1 - 0.0085 15.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 OIR58038.1 - 0.016 15.5 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OIR58038.1 - 0.022 14.5 0.1 0.63 9.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 OIR58038.1 - 0.026 14.5 0.2 11 6.0 0.1 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 OIR58038.1 - 0.031 13.5 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 OIR58038.1 - 0.05 13.5 0.0 3.6 7.5 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_19 PF13245.6 OIR58038.1 - 0.057 13.8 0.2 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OIR58038.1 - 0.076 12.8 0.5 8.4 6.1 0.0 3.0 2 1 1 3 3 3 0 DEAD/DEAH box helicase AFG1_ATPase PF03969.16 OIR58038.1 - 0.083 11.8 0.0 3.4 6.4 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase TniB PF05621.11 OIR58038.1 - 0.13 11.6 1.2 4.8 6.6 0.0 3.3 3 1 1 4 4 3 0 Bacterial TniB protein DAP3 PF10236.9 OIR58038.1 - 0.15 11.2 0.1 5 6.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.9 OIR58038.1 - 0.25 10.5 0.7 0.75 9.0 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Actin PF00022.19 OIR58039.1 - 1e-146 488.8 0.0 3.6e-146 486.9 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 OIR58039.1 - 0.067 13.1 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain MOZ_SAS PF01853.18 OIR58040.1 - 8e-74 247.2 0.1 1.4e-73 246.3 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OIR58040.1 - 2.5e-22 78.2 1.1 5.4e-22 77.1 1.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OIR58040.1 - 8.9e-12 44.7 0.1 2e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OIR58040.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OIR58040.1 - 0.026 14.7 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ADK PF00406.22 OIR58042.1 - 1.9e-20 73.5 0.0 2.9e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OIR58042.1 - 3.2e-16 60.0 0.0 4.5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OIR58042.1 - 1.2e-08 35.6 0.0 1.9e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR58042.1 - 8.4e-07 29.2 2.1 0.00019 21.6 2.1 2.3 1 1 0 1 1 1 1 AAA domain Ploopntkinase1 PF18748.1 OIR58042.1 - 0.018 14.6 0.0 4.3 6.8 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 dNK PF01712.19 OIR58042.1 - 0.032 14.1 0.2 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 OIR58042.1 - 0.07 12.4 0.1 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Thymidylate_kin PF02223.17 OIR58042.1 - 0.13 12.0 0.8 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase PFK PF00365.20 OIR58043.1 - 1.8e-170 565.6 4.1 3.4e-102 341.6 0.1 2.2 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 OIR58043.1 - 0.042 13.5 0.4 5 6.7 0.1 2.7 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Nsp1_C PF05064.13 OIR58044.1 - 2.5e-20 72.4 7.0 2.5e-20 72.4 7.0 1.8 1 1 1 2 2 2 1 Nsp1-like C-terminal region APG6_N PF17675.1 OIR58044.1 - 0.0052 17.3 7.2 0.0052 17.3 7.2 2.6 2 1 0 2 2 2 1 Apg6 coiled-coil region SKA1 PF07160.12 OIR58044.1 - 0.0076 16.1 4.8 0.0076 16.1 4.8 2.0 1 1 0 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF724 PF05266.14 OIR58044.1 - 0.014 15.2 5.6 0.014 15.2 5.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) PilO PF04350.13 OIR58044.1 - 0.016 15.4 8.6 0.25 11.5 0.2 2.8 2 1 0 2 2 2 0 Pilus assembly protein, PilO Sec8_exocyst PF04048.14 OIR58044.1 - 0.025 14.5 8.3 0.051 13.5 2.9 2.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF45 PF01863.17 OIR58044.1 - 0.047 13.7 1.5 0.089 12.8 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF4200 PF13863.6 OIR58044.1 - 0.087 13.2 25.8 0.03 14.7 8.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 OIR58044.1 - 0.26 10.6 16.3 0.49 9.7 16.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 OIR58044.1 - 0.45 10.7 20.9 0.025 14.8 12.8 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.9 OIR58044.1 - 0.78 10.0 12.8 4.3 7.6 12.8 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein Sec34 PF04136.15 OIR58044.1 - 0.86 9.5 10.1 1.2 9.0 3.5 2.3 2 0 0 2 2 2 0 Sec34-like family Occludin_ELL PF07303.13 OIR58044.1 - 1.2 9.9 9.5 3.7 8.3 2.4 3.2 2 2 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 OIR58044.1 - 1.2 9.2 11.5 0.29 11.2 4.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 OIR58044.1 - 1.3 9.0 9.3 1.3 9.1 1.8 2.5 2 0 0 2 2 2 0 Laminin Domain II BRE1 PF08647.11 OIR58044.1 - 2.8 8.1 25.0 0.092 12.8 8.5 4.0 2 2 0 3 3 3 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 OIR58044.1 - 3.9 7.7 22.7 21 5.4 8.4 3.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 OIR58044.1 - 6.4 6.1 21.4 0.34 10.2 10.8 2.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 OIR58044.1 - 7.6 5.0 14.3 1.7 7.2 6.8 2.0 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.9 OIR58044.1 - 9.5 6.6 12.9 12 6.3 5.2 3.4 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADK PF00406.22 OIR58045.1 - 7.5e-29 100.8 0.0 9e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OIR58045.1 - 2.4e-20 73.3 0.3 2.9e-20 73.1 0.3 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OIR58045.1 - 9.5e-11 42.4 0.5 1.5e-10 41.7 0.5 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR58045.1 - 3.2e-07 30.6 0.0 4.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 OIR58045.1 - 0.00069 19.8 0.5 0.0011 19.1 0.5 1.3 1 1 0 1 1 1 1 Shikimate kinase Hydin_ADK PF17213.3 OIR58045.1 - 0.0012 19.2 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 OIR58045.1 - 0.0098 16.2 0.2 0.019 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OIR58045.1 - 0.015 15.0 0.0 0.023 14.5 0.0 1.3 1 1 0 1 1 1 0 Cytidylate kinase AAA PF00004.29 OIR58045.1 - 0.024 15.1 0.2 0.031 14.7 0.2 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 OIR58045.1 - 0.027 14.4 0.0 0.9 9.4 0.0 2.2 1 1 1 2 2 2 0 P-loop Nucleotide Kinase3 dNK PF01712.19 OIR58045.1 - 0.031 14.1 0.4 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 OIR58045.1 - 0.11 12.4 0.1 0.63 9.9 0.1 2.0 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 OIR58045.1 - 0.16 11.2 0.5 5.5 6.2 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 OIR58045.1 - 0.21 12.0 0.2 0.48 10.8 0.2 1.8 1 1 0 1 1 1 0 RNA helicase DUF641 PF04859.12 OIR58046.1 - 0.0094 16.3 8.8 0.0094 16.3 8.8 7.0 4 2 3 8 8 8 1 Plant protein of unknown function (DUF641) KELK PF15796.5 OIR58046.1 - 0.024 15.1 4.6 0.024 15.1 4.6 9.7 4 2 5 10 10 10 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GIT_CC PF16559.5 OIR58046.1 - 1.2 9.1 11.0 4.7 7.2 0.1 5.4 5 1 1 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor NUDIX_2 PF13869.6 OIR58046.1 - 2.8 7.5 9.3 32 4.0 0.2 4.6 4 0 0 4 4 4 0 Nucleotide hydrolase Beta-Casp PF10996.8 OIR58047.1 - 2.1e-26 92.3 0.0 4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 OIR58047.1 - 9.3e-22 78.0 0.1 2.8e-21 76.4 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OIR58047.1 - 1.6e-19 70.1 0.0 3.7e-19 68.9 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 OIR58047.1 - 1.1e-11 44.5 0.0 2.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CPSF73-100_C PF11718.8 OIR58047.1 - 3e-10 40.0 0.0 4.9e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.7 OIR58047.1 - 3e-08 33.4 0.5 8.6e-08 31.9 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OIR58047.1 - 0.00031 20.7 0.0 0.00089 19.2 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain UCH PF00443.29 OIR58048.1 - 1.1e-10 41.5 0.1 1.1e-10 41.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR58048.1 - 0.042 13.4 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Asn_synthase PF00733.21 OIR58049.1 - 1.1e-14 54.9 0.1 4.6e-06 26.5 0.1 2.5 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OIR58049.1 - 0.011 15.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase domain PAPS_reduct PF01507.19 OIR58049.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 OIR58049.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 PP-loop family TPR_12 PF13424.6 OIR58050.1 - 7.2e-06 26.2 5.2 0.21 11.9 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OIR58050.1 - 0.001 19.0 4.3 19 5.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OIR58050.1 - 0.0043 16.9 1.8 1.5 8.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OIR58050.1 - 0.037 14.2 6.5 26 5.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 OIR58050.1 - 0.051 14.1 11.4 0.69 10.5 1.6 4.7 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OIR58050.1 - 6.5 7.9 15.8 52 5.0 0.1 6.3 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 OIR58050.1 - 7 7.6 10.2 7.2 7.6 0.5 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 OIR58051.1 - 1.1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58051.1 - 2.9e-14 53.0 0.0 4.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DFRP_C PF16543.5 OIR58052.1 - 2.2e-18 66.5 1.9 2.2e-18 66.5 1.9 2.9 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 OIR58052.1 - 8.8e-07 29.6 3.7 8.8e-06 26.4 0.7 3.0 1 1 1 2 2 2 1 Torus domain zf-CCCH PF00642.24 OIR58052.1 - 0.00011 22.1 0.8 0.00011 22.1 0.8 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OIR58052.1 - 0.00047 19.9 1.3 0.00047 19.9 1.3 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OIR58052.1 - 0.0038 17.2 5.5 0.0038 17.2 5.5 3.0 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_3 PF15663.5 OIR58052.1 - 0.1 12.8 1.3 0.51 10.6 0.2 2.4 1 1 0 2 2 2 0 Zinc-finger containing family PAXNEB PF05625.11 OIR58053.1 - 5e-16 58.8 0.0 8.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 PAXNEB protein zf-RING_2 PF13639.6 OIR58056.1 - 2.6e-08 34.1 8.5 5.8e-08 32.9 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OIR58056.1 - 4.2e-06 26.6 4.7 1.1e-05 25.3 4.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OIR58056.1 - 4.8e-05 23.0 4.3 4.8e-05 23.0 4.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OIR58056.1 - 8.5e-05 22.3 5.3 0.00018 21.3 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OIR58056.1 - 0.00026 21.0 2.6 0.00026 21.0 2.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OIR58056.1 - 0.00038 20.2 7.3 0.00097 18.9 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TniQ PF06527.11 OIR58056.1 - 0.0032 18.2 0.5 0.0051 17.5 0.5 1.4 1 0 0 1 1 1 1 TniQ zf-C3HC4 PF00097.25 OIR58056.1 - 0.014 15.2 6.4 0.033 14.0 6.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RAMP4 PF06624.12 OIR58056.1 - 0.019 15.0 0.2 0.019 15.0 0.2 2.1 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Rad50_zn_hook PF04423.14 OIR58056.1 - 0.11 12.3 4.0 1.4 8.9 0.5 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 OIR58056.1 - 0.13 12.2 8.3 3.9 7.4 8.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-FPG_IleRS PF06827.14 OIR58056.1 - 0.19 11.6 4.2 2.8 7.9 0.1 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 OIR58056.1 - 0.22 11.7 2.5 18 5.6 0.5 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_17 PF17120.5 OIR58056.1 - 0.39 10.4 8.0 1.1 8.9 8.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OIR58056.1 - 1.1 9.4 9.9 0.66 10.1 3.2 2.8 2 1 0 2 2 2 0 Zinc-finger zf-rbx1 PF12678.7 OIR58056.1 - 2 8.8 10.5 14 6.1 10.5 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Di19 PF05605.12 OIR58056.1 - 6.1 7.2 8.5 3.9 7.8 1.7 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding TF_Zn_Ribbon PF08271.12 OIR58057.1 - 0.027 14.0 2.9 0.06 12.9 2.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3297 PF11730.8 OIR58057.1 - 0.11 12.4 0.1 0.37 10.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) LSM PF01423.22 OIR58058.1 - 5.4e-15 54.8 0.0 6e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OIR58058.1 - 0.027 14.6 0.0 0.032 14.4 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain KTI12 PF08433.10 OIR58059.1 - 2.1e-43 148.7 0.0 2.3e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OIR58059.1 - 7.1e-09 36.0 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 OIR58059.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 OIR58059.1 - 0.0039 17.5 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OIR58059.1 - 0.004 16.5 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 OIR58059.1 - 0.02 15.4 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OIR58059.1 - 0.023 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 OIR58059.1 - 0.027 14.1 0.3 0.29 10.8 0.3 2.1 1 1 0 1 1 1 0 Thymidylate kinase AAA_28 PF13521.6 OIR58059.1 - 0.044 14.0 0.2 0.089 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 OIR58059.1 - 0.2 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CKS PF01111.19 OIR58060.1 - 3e-34 117.1 3.1 3.6e-34 116.9 3.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Acetyltransf_1 PF00583.25 OIR58062.1 - 1.9e-09 37.8 0.2 2.3e-09 37.5 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OIR58062.1 - 3.2e-08 33.6 0.1 4.2e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR58062.1 - 6.2e-06 26.6 0.3 9.6e-06 25.9 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LrgA PF03788.14 OIR58062.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 LrgA family RNA_pol_Rpb2_6 PF00562.28 OIR58064.1 - 3.3e-102 342.5 0.0 1.3e-101 340.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OIR58064.1 - 1.4e-30 106.4 0.0 2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OIR58064.1 - 1.8e-22 79.3 0.0 4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 OIR58064.1 - 6.6e-21 74.5 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 OIR58064.1 - 1.7e-17 63.7 0.1 3.2e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 OIR58064.1 - 4.7e-09 36.1 0.1 1.3e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain Zn-ribbon_8 PF09723.10 OIR58064.1 - 0.071 13.2 0.5 0.21 11.8 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Cyclin PF08613.11 OIR58065.1 - 3.4e-06 27.5 0.8 4.3e-06 27.2 0.8 1.3 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OIR58065.1 - 0.034 13.9 0.4 0.074 12.8 0.4 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain ASFV_p27 PF06556.11 OIR58065.1 - 0.035 14.2 0.6 0.092 12.9 0.1 1.9 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus WD40_like PF17005.5 OIR58066.1 - 1.5e-05 24.4 0.1 5.7e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 WD40-like domain WD40 PF00400.32 OIR58066.1 - 8.6e-05 23.2 4.9 0.047 14.6 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 OIR58066.1 - 0.049 13.7 0.0 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CRT10 PF08728.10 OIR58066.1 - 0.13 10.4 0.2 0.28 9.3 0.2 1.5 1 0 0 1 1 1 0 CRT10 Sen15 PF09631.10 OIR58066.1 - 0.17 12.2 0.0 8.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Sen15 protein tRNA-synt_2b PF00587.25 OIR58067.1 - 2.2e-33 115.7 0.0 4.2e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OIR58067.1 - 5.1e-18 65.0 0.4 9.2e-18 64.2 0.4 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 OIR58067.1 - 1.6e-12 47.3 0.0 3.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain FA_synthesis PF02504.15 OIR58067.1 - 0.044 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthesis protein Arf PF00025.21 OIR58069.1 - 6.8e-67 224.3 0.0 8.2e-67 224.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OIR58069.1 - 2.1e-13 50.5 0.0 2.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OIR58069.1 - 2e-12 47.0 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OIR58069.1 - 6.3e-11 42.0 0.0 7.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OIR58069.1 - 4.7e-10 39.2 0.1 8.7e-07 28.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OIR58069.1 - 4.7e-09 35.9 0.0 5.8e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OIR58069.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 OIR58069.1 - 0.00033 19.7 0.1 0.0086 15.1 0.1 2.5 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 OIR58069.1 - 0.025 14.1 0.2 0.062 12.8 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 OIR58069.1 - 0.11 12.1 0.1 8.8 5.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OIR58069.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain HAUS6_N PF14661.6 OIR58070.1 - 1.3 8.5 8.6 1.9 8.0 8.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_A22B PF04258.13 OIR58071.1 - 3.7e-61 207.1 7.5 4.8e-61 206.8 7.5 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DPM3 PF08285.11 OIR58071.1 - 0.012 15.8 8.5 0.16 12.2 0.0 3.7 2 1 2 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Cullin PF00888.22 OIR58072.1 - 5e-35 121.2 0.0 5.9e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Cullin family Ribosomal_S8e PF01201.22 OIR58073.1 - 5.8e-48 162.5 2.0 6.8e-48 162.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e NTP_transferase PF00483.23 OIR58074.1 - 3.3e-07 30.1 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 OIR58074.1 - 0.00012 22.5 0.0 0.0003 21.2 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 OIR58074.1 - 0.00021 20.9 3.5 0.28 11.0 0.0 3.2 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 OIR58074.1 - 0.012 13.8 0.1 0.016 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 OIR58074.1 - 4.6 7.1 5.7 6.8e+02 0.1 5.7 3.0 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase AAA PF00004.29 OIR58075.1 - 1.9e-41 141.6 0.0 1.5e-40 138.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR58075.1 - 1.6e-09 37.4 0.1 4.4e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OIR58075.1 - 7.1e-09 36.0 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OIR58075.1 - 0.00013 22.4 0.1 0.53 10.6 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OIR58075.1 - 0.00014 22.1 0.0 0.0026 18.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OIR58075.1 - 0.0014 18.7 0.0 0.013 15.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 OIR58075.1 - 0.004 16.7 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 OIR58075.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 OIR58075.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OIR58075.1 - 0.024 15.2 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OIR58075.1 - 0.027 14.8 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 OIR58075.1 - 0.03 13.7 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 OIR58075.1 - 0.041 13.6 0.1 0.44 10.3 0.0 2.6 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 OIR58075.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 OIR58075.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.8 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 OIR58075.1 - 0.16 11.8 0.6 1.1 9.2 0.2 2.7 2 1 0 2 2 2 0 NACHT domain Glyco_transf_64 PF09258.10 OIR58076.1 - 8.5e-19 67.8 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 OIR58076.1 - 6.6e-16 58.6 2.8 4.4e-14 52.7 2.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 OIR58076.1 - 0.0054 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HSP70 PF00012.20 OIR58077.1 - 1.2e-38 132.7 40.4 5.3e-36 124.0 40.4 3.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OIR58077.1 - 5.2e-06 25.5 2.0 1.4e-05 24.1 2.0 1.7 1 0 0 1 1 1 1 MreB/Mbl protein ATP_bind_3 PF01171.20 OIR58078.1 - 8.1e-18 64.8 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 OIR58078.1 - 0.0024 17.4 2.4 0.0024 17.4 2.4 2.8 2 0 0 2 2 2 1 Zinc-ribbon RecR PF02132.15 OIR58078.1 - 0.02 14.4 1.3 0.02 14.4 1.3 3.3 4 0 0 4 4 4 0 RecR protein LSM PF01423.22 OIR58079.1 - 1.7e-12 46.8 0.0 2.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OIR58079.1 - 0.01 16.0 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OIR58079.1 - 0.028 14.5 0.1 0.031 14.4 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain NatB_MDM20 PF09797.9 OIR58080.1 - 2.9e-08 33.1 0.1 6.4e-06 25.3 0.0 2.3 2 0 0 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit ParA PF10609.9 OIR58081.1 - 1.6e-70 237.4 0.0 2.1e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OIR58081.1 - 5.4e-11 42.6 0.0 1.8e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OIR58081.1 - 4e-08 33.4 0.8 6e-07 29.6 0.2 2.5 1 1 1 3 3 3 1 AAA domain ArsA_ATPase PF02374.15 OIR58081.1 - 1.8e-05 24.1 0.2 1.8e-05 24.1 0.2 2.7 2 1 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 OIR58081.1 - 0.00089 18.6 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ RsgA_GTPase PF03193.16 OIR58081.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase CLP1_P PF16575.5 OIR58081.1 - 0.0027 17.5 0.2 0.019 14.8 0.1 2.2 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 OIR58081.1 - 0.0035 16.9 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 OIR58081.1 - 0.005 16.7 0.0 0.09 12.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 OIR58081.1 - 0.013 15.0 0.1 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OIR58081.1 - 0.015 14.9 0.3 0.54 9.9 0.2 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 OIR58081.1 - 0.022 15.0 0.1 4.2 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2201 PF09967.9 OIR58081.1 - 0.03 14.4 0.1 6.7 6.9 0.0 2.3 2 0 0 2 2 2 0 VWA-like domain (DUF2201) NADH-G_4Fe-4S_3 PF10588.9 OIR58081.1 - 0.063 12.8 3.5 0.22 11.1 0.8 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zeta_toxin PF06414.12 OIR58081.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cpYpsA PF12694.7 OIR58081.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family Glycogen_syn PF05693.13 OIR58083.1 - 0.045 12.3 0.3 0.063 11.8 0.3 1.1 1 0 0 1 1 1 0 Glycogen synthase zf-ANAPC11 PF12861.7 OIR58084.1 - 2e-22 79.1 15.7 2.3e-22 78.9 15.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OIR58084.1 - 8.5e-15 54.8 16.1 1.3e-14 54.2 16.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OIR58084.1 - 1.5e-08 34.8 16.3 3.3e-07 30.5 16.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OIR58084.1 - 2.4e-05 24.1 12.1 5.8e-05 22.9 12.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR58084.1 - 0.00037 20.4 15.6 0.0015 18.4 15.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OIR58084.1 - 0.00062 19.6 18.2 0.00098 18.9 14.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 OIR58084.1 - 0.0011 19.2 4.3 0.0011 19.2 4.3 2.3 2 0 0 2 2 2 1 RING-like domain zf-RING_UBOX PF13445.6 OIR58084.1 - 0.005 16.8 11.9 0.013 15.5 10.1 2.3 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OIR58084.1 - 0.038 13.6 20.6 0.15 11.7 20.0 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OIR58084.1 - 0.041 13.8 18.0 0.15 11.9 13.9 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 OIR58084.1 - 0.38 10.9 13.5 7.3 6.8 13.5 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger zf-Nse PF11789.8 OIR58084.1 - 0.87 9.5 9.7 2.2 8.2 9.7 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OIR58084.1 - 2.2 8.5 17.6 20 5.4 17.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Di19 PF05605.12 OIR58084.1 - 8.8 6.7 20.5 3.5 8.0 12.5 3.2 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Septin PF00735.18 OIR58085.1 - 7.1e-31 107.5 0.8 1e-29 103.7 0.8 2.0 1 1 0 1 1 1 1 Septin SIS PF01380.22 OIR58086.1 - 5.5e-54 181.5 0.0 5.7e-32 110.3 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OIR58086.1 - 2e-16 60.4 0.0 3.6e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OIR58086.1 - 4.2e-10 39.6 0.0 8.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OIR58086.1 - 4.3e-05 22.5 0.0 6.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF2529 PF10740.9 OIR58086.1 - 0.016 14.8 0.0 5 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) RNA_pol_Rpb4 PF03874.16 OIR58087.1 - 1.7e-10 41.3 0.0 3e-09 37.3 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase Rpb4 Gaa1 PF04114.14 OIR58088.1 - 1e-05 24.8 1.5 0.048 12.7 0.0 2.6 3 0 0 3 3 3 2 Gaa1-like, GPI transamidase component zf-RVT PF13966.6 OIR58089.1 - 0.014 16.1 1.8 0.014 16.1 1.8 1.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase FeThRed_B PF02943.15 OIR58089.1 - 0.029 14.4 2.7 0.047 13.7 2.7 1.3 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Dopey_N PF04118.14 OIR58090.1 - 4.2e-59 200.2 0.0 1.5e-58 198.4 0.0 2.0 2 0 0 2 2 2 1 Dopey, N-terminal Acetyltransf_7 PF13508.7 OIR58091.1 - 3.8e-09 36.8 0.0 9.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OIR58091.1 - 3.9e-07 29.8 0.0 9.9e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_1 PF00583.25 OIR58091.1 - 1.8e-06 28.2 0.0 4.8e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 OIR58091.1 - 7.7e-06 25.8 0.0 4.9e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 OIR58091.1 - 0.0004 20.5 0.0 0.00089 19.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OIR58091.1 - 0.0017 18.3 0.0 0.0089 16.0 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OIR58091.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Helicase_C PF00271.31 OIR58092.1 - 3.8e-15 56.2 0.1 1.2e-14 54.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 OIR58092.1 - 8e-15 55.1 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 OIR58092.1 - 0.0001 22.1 1.0 0.00021 21.1 0.2 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OIR58092.1 - 0.00044 20.5 0.3 0.0031 17.8 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OIR58092.1 - 0.00095 18.9 0.9 0.0018 18.0 0.2 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OIR58092.1 - 0.013 15.8 0.2 0.039 14.3 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OIR58092.1 - 0.014 15.5 0.1 0.037 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OIR58092.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 OIR58092.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 OIR58092.1 - 0.064 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 OIR58092.1 - 0.084 13.4 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CoA_binding_2 PF13380.6 OIR58092.1 - 0.11 13.0 0.3 15 6.1 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain AAA_24 PF13479.6 OIR58092.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain NOG1_N PF17835.1 OIR58093.1 - 9.9e-51 171.9 0.8 2.2e-50 170.7 0.8 1.6 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 OIR58093.1 - 1.7e-25 88.6 0.1 3.9e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 OIR58093.1 - 3.1e-22 78.3 0.2 7.2e-22 77.1 0.2 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 OIR58093.1 - 1.4e-17 63.9 0.0 3.2e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OIR58093.1 - 4.7e-10 39.2 0.0 9.7e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 OIR58093.1 - 0.00039 19.8 0.1 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 OIR58093.1 - 0.006 16.7 0.9 1.4 8.9 0.0 3.4 4 1 1 5 5 5 1 Dynamin family RsgA_GTPase PF03193.16 OIR58093.1 - 0.0069 16.3 0.1 0.21 11.5 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase DUF4618 PF15397.6 OIR58093.1 - 0.0083 15.6 2.0 0.046 13.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) PPV_E1_C PF00519.17 OIR58093.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase PGI PF00342.19 OIR58094.1 - 7.6e-213 707.5 0.1 8.6e-213 707.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase STT3 PF02516.14 OIR58095.1 - 9.6e-51 173.2 7.5 1.3e-40 139.8 4.2 2.1 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 OIR58095.1 - 2.8e-05 24.4 4.8 2.8e-05 24.4 4.8 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Dpy19 PF10034.9 OIR58095.1 - 3.4 5.8 9.3 0.14 10.3 0.3 2.0 1 1 1 2 2 2 0 Q-cell neuroblast polarisation Pkinase PF00069.25 OIR58096.1 - 9e-54 182.6 0.1 1.5e-53 181.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58096.1 - 4.7e-39 134.2 0.1 9.3e-39 133.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase OSR1_C PF12202.8 OIR58096.1 - 3.4e-05 24.0 0.0 8.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain APH PF01636.23 OIR58096.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cnd3 PF12719.7 OIR58097.1 - 2e-35 122.4 0.2 1.2e-34 119.8 0.0 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 OIR58097.1 - 4.7e-08 32.6 0.8 1.5 9.3 0.0 6.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 OIR58097.1 - 5.9e-05 23.2 0.2 0.77 9.8 0.0 4.1 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OIR58097.1 - 0.0013 19.0 10.5 0.53 10.7 1.3 4.8 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 OIR58097.1 - 0.024 15.1 5.8 20 5.8 0.7 4.9 4 0 0 4 4 4 0 HEAT-like repeat Arm_2 PF04826.13 OIR58097.1 - 0.037 13.5 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Armadillo-like Cohesin_HEAT PF12765.7 OIR58097.1 - 0.037 14.3 5.6 4.2 7.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion TFCD_C PF12612.8 OIR58097.1 - 0.08 12.8 0.5 2.1 8.1 0.0 2.9 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal NopRA1 PF16201.5 OIR58097.1 - 0.15 11.6 2.3 1.7 8.2 0.0 3.2 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 MFS_1 PF07690.16 OIR58098.1 - 1.5e-52 178.7 25.4 1.5e-52 178.7 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OIR58098.1 - 6.1e-05 21.7 27.1 0.0069 15.0 9.2 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein ESSS PF10183.9 OIR58098.1 - 0.5 10.6 2.3 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-AN1 PF01428.16 OIR58099.1 - 4.5e-10 39.5 10.5 4.5e-10 39.5 10.5 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger Myticin-prepro PF10690.9 OIR58099.1 - 4.4 7.6 13.9 11 6.3 13.9 1.7 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Tau95 PF09734.9 OIR58100.1 - 1.4e-18 68.0 0.7 3.6e-18 66.7 0.7 1.8 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OIR58100.1 - 3.4e-09 37.0 0.0 3.3e-08 33.8 0.0 2.1 1 1 1 2 2 2 1 Tau95 Triple barrel domain Phage_int_SAM_3 PF14659.6 OIR58100.1 - 0.058 13.7 1.1 1.7 9.0 0.1 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain FeS_assembly_P PF01883.19 OIR58103.1 - 4.3e-10 39.6 0.0 7.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein TFIIB PF00382.19 OIR58104.1 - 3.7e-36 123.0 2.8 5.6e-19 68.0 0.8 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OIR58104.1 - 2e-12 46.4 2.0 3.6e-12 45.6 2.0 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OIR58104.1 - 7.8e-06 25.7 0.5 0.037 13.8 0.1 2.2 1 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OIR58104.1 - 0.0011 19.0 2.2 0.0074 16.4 0.6 2.3 1 1 1 2 2 2 1 Cyclin, C-terminal domain HTH_28 PF13518.6 OIR58104.1 - 0.0081 16.3 0.4 0.055 13.6 0.0 2.3 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 OIR58104.1 - 0.013 15.1 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.6 OIR58104.1 - 0.028 14.2 0.4 0.16 11.8 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 OIR58104.1 - 0.041 13.4 0.1 0.35 10.5 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RB_B PF01857.20 OIR58104.1 - 0.059 13.4 1.9 0.18 11.8 0.3 2.1 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain HTH_AsnC-type PF13404.6 OIR58104.1 - 0.087 12.7 0.1 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain HTH_29 PF13551.6 OIR58104.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix HTH_IclR PF09339.10 OIR58104.1 - 0.2 11.5 0.4 1.3 8.9 0.1 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain zf-FCS PF06467.14 OIR58104.1 - 0.27 11.2 1.2 0.52 10.3 0.2 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.6 OIR58104.1 - 2.2 7.8 4.6 4.2 6.9 0.4 2.9 3 0 0 3 3 3 0 zinc-ribbon domain LRR_8 PF13855.6 OIR58106.1 - 4.4e-26 90.4 34.5 1.2e-08 34.5 0.8 3.4 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 OIR58106.1 - 5.4e-10 39.4 13.1 0.0014 19.0 1.1 4.3 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OIR58106.1 - 3.2e-06 26.8 7.3 0.0057 16.2 0.7 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 OIR58106.1 - 0.0017 18.6 13.8 6.6 7.7 1.5 5.7 4 3 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 OIR58106.1 - 0.023 14.7 14.4 3.7 7.8 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Brix PF04427.18 OIR58107.1 - 1.5e-11 44.7 0.0 2.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain YABBY PF04690.13 OIR58108.1 - 1.1e-17 65.0 6.0 1.2e-17 64.9 6.0 1.0 1 0 0 1 1 1 1 YABBY protein HMG_box_2 PF09011.10 OIR58108.1 - 3.6e-07 30.7 1.9 3.6e-07 30.7 1.9 1.6 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.19 OIR58108.1 - 2e-06 28.1 1.9 2e-06 28.1 1.9 1.7 1 1 1 2 2 2 1 HMG (high mobility group) box Ccdc124 PF06244.12 OIR58108.1 - 0.0018 18.8 7.9 0.0032 18.0 7.9 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 SHD1 PF03983.12 OIR58109.1 - 2e-09 37.1 0.0 4.5e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 Glyco_tranf_2_3 PF13641.6 OIR58110.1 - 0.0035 17.2 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1697 PF08002.11 OIR58110.1 - 0.084 13.3 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Ribosomal_L39 PF00832.20 OIR58111.1 - 1.7e-16 59.6 11.1 2e-16 59.3 11.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.18 OIR58111.1 - 0.06 13.4 2.9 0.066 13.2 2.9 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF4267 PF14087.6 OIR58112.1 - 0.082 13.0 1.1 1.9 8.6 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4267) UMPH-1 PF05822.12 OIR58114.1 - 0.01 15.4 0.1 0.04 13.4 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) LBP_BPI_CETP PF01273.25 OIR58114.1 - 0.074 12.7 0.1 12 5.4 0.0 2.5 1 1 1 2 2 2 0 LBP / BPI / CETP family, N-terminal domain RVT_1 PF00078.27 OIR58116.1 - 2.4e-36 125.3 0.0 3.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mlp PF03304.13 OIR58117.1 - 0.013 15.7 2.3 0.019 15.2 2.3 1.2 1 0 0 1 1 1 0 Mlp lipoprotein family DUF4335 PF14233.6 OIR58118.1 - 0.058 13.3 0.3 0.14 12.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) CCDC84 PF14968.6 OIR58118.1 - 1.9 8.0 8.1 1.1 8.9 5.2 2.2 1 1 1 2 2 2 0 Coiled coil protein 84 PAP_central PF04928.17 OIR58118.1 - 8.2 5.3 6.5 5.7 5.8 0.0 2.7 3 0 0 3 3 3 0 Poly(A) polymerase central domain Ribosomal_L30 PF00327.20 OIR58120.1 - 0.035 14.0 0.0 0.77 9.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e Auxin_inducible PF02519.14 OIR58122.1 - 0.058 13.6 0.1 0.083 13.1 0.1 1.4 1 1 0 1 1 1 0 Auxin responsive protein ARPC4 PF05856.12 OIR58123.1 - 1.2e-25 90.1 0.0 1.4e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3784 PF12650.7 OIR58124.1 - 2.2 8.5 14.0 6.7 7.0 2.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) NAD_kinase PF01513.21 OIR58125.1 - 4.4e-37 127.9 0.0 7.9e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OIR58125.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF357 PF04010.13 OIR58125.1 - 0.15 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF357) SRA1 PF07304.11 OIR58126.1 - 5.7e-11 42.4 0.1 5.7e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 OIR58126.1 - 2.8e-07 31.1 9.0 0.00039 21.2 0.2 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58126.1 - 3e-06 27.4 0.0 0.0031 17.8 0.1 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 OIR58126.1 - 0.00059 19.6 0.1 0.0021 17.8 0.0 2.0 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 OIR58126.1 - 0.091 12.8 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Prp18 domain ubiquitin PF00240.23 OIR58128.1 - 2.6e-18 65.5 0.1 2.9e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OIR58128.1 - 6.2e-09 35.6 0.1 6.8e-09 35.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OIR58128.1 - 0.019 15.4 0.0 0.079 13.4 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain YukD PF08817.10 OIR58128.1 - 0.06 14.1 0.1 0.078 13.7 0.1 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD TnpB_IS66 PF05717.13 OIR58128.1 - 0.15 12.0 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 IS66 Orf2 like protein TBK1_ULD PF18396.1 OIR58128.1 - 0.18 11.8 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain NTP_transferase PF00483.23 OIR58129.1 - 1.4e-50 172.2 0.0 1.9e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 OIR58129.1 - 5.3e-12 45.0 10.2 2e-07 30.5 0.9 3.6 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OIR58129.1 - 3.1e-08 34.1 0.0 4.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 OIR58129.1 - 0.00016 21.3 2.4 0.0018 17.9 0.5 4.4 2 1 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 OIR58129.1 - 0.0032 15.7 2.0 0.0032 15.7 2.0 2.0 2 1 1 3 3 3 2 Domain of unknown function (DUF4954) Fucokinase PF07959.12 OIR58129.1 - 0.023 13.7 0.6 0.34 9.8 0.3 2.1 2 0 0 2 2 2 0 L-fucokinase Ribosomal_L24e PF01246.20 OIR58130.1 - 5.2e-23 81.1 0.7 5.2e-23 81.1 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2951 PF11166.8 OIR58130.1 - 1.3 9.3 5.1 1.7 8.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) YIF1 PF03878.15 OIR58131.1 - 5e-50 170.2 4.3 6.1e-50 170.0 4.3 1.0 1 0 0 1 1 1 1 YIF1 PUA PF01472.20 OIR58132.1 - 4.6e-12 45.7 1.7 8.2e-12 44.9 1.7 1.4 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 OIR58132.1 - 8.6e-10 39.2 0.1 1.4e-09 38.5 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain Fis1_TPR_C PF14853.6 OIR58133.1 - 2.3e-15 56.4 0.3 2.3e-15 56.4 0.3 1.8 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OIR58133.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OIR58133.1 - 0.02 15.1 0.1 0.21 11.8 0.0 2.0 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OIR58133.1 - 0.021 15.3 0.3 0.12 12.9 0.1 2.1 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF883 PF05957.13 OIR58133.1 - 0.029 15.0 0.2 0.33 11.6 0.0 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF543 PF04418.12 OIR58133.1 - 0.054 13.5 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) SecY PF00344.20 OIR58134.1 - 2.8e-60 204.2 13.0 3.6e-60 203.8 13.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OIR58134.1 - 3.6e-17 61.9 0.1 1.1e-16 60.4 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Chitin_synth_2 PF03142.15 OIR58135.1 - 1.1e-62 212.4 4.7 1.3e-62 212.1 4.7 1.0 1 0 0 1 1 1 1 Chitin synthase F-box PF00646.33 OIR58135.1 - 0.027 14.4 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain CbiQ PF02361.16 OIR58135.1 - 2.4 7.7 10.4 3.2 7.3 10.4 1.2 1 0 0 1 1 1 0 Cobalt transport protein NAD_kinase PF01513.21 OIR58137.1 - 4.3e-30 104.9 0.0 5.6e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase AF0941-like PF14591.6 OIR58139.1 - 0.11 13.1 0.4 0.61 10.7 0.1 2.2 2 0 0 2 2 2 0 AF0941-like Exostosin PF03016.15 OIR58140.1 - 1.2e-06 28.0 0.8 8.7e-06 25.2 0.8 2.0 1 1 0 1 1 1 1 Exostosin family Glycos_transf_1 PF00534.20 OIR58140.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OIR58140.1 - 0.0073 16.7 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ArfGap PF01412.18 OIR58141.1 - 9.6e-36 122.4 1.2 1.6e-35 121.7 1.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 OIR58141.1 - 4e-06 26.6 0.0 7.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 OIR58141.1 - 0.02 14.6 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 CUE domain HOIP-UBA PF16678.5 OIR58141.1 - 0.11 12.4 0.7 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 HOIP UBA domain pair UBA_4 PF14555.6 OIR58141.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain PI3_PI4_kinase PF00454.27 OIR58142.1 - 1.6e-47 162.4 0.0 3.2e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OIR58142.1 - 1.1e-09 38.0 0.0 2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 FATC domain TPR_12 PF13424.6 OIR58142.1 - 0.0033 17.7 0.3 1.4 9.2 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat FAT PF02259.23 OIR58142.1 - 0.0042 16.4 0.0 0.015 14.5 0.0 1.9 1 1 0 1 1 1 1 FAT domain TPR_10 PF13374.6 OIR58142.1 - 0.019 14.9 0.0 4.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OIR58142.1 - 0.099 13.3 0.1 55 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Osmo_CC PF08946.10 OIR58142.1 - 0.13 12.6 0.3 0.54 10.5 0.4 2.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil PsaX PF08078.12 OIR58142.1 - 0.89 9.6 2.6 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 PsaX family CS PF04969.16 OIR58143.1 - 8.4e-09 36.3 0.0 1.1e-08 35.9 0.0 1.2 1 0 0 1 1 1 1 CS domain Ribosomal_L6e PF01159.19 OIR58144.1 - 6.2e-11 42.8 0.0 1.7e-09 38.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein L6e Rep_fac-A_3 PF08661.11 OIR58146.1 - 0.0014 18.9 0.0 0.0017 18.7 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Myosin_N PF02736.19 OIR58146.1 - 0.075 12.9 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Glyco_transf_64 PF09258.10 OIR58147.1 - 4.3e-63 212.9 0.0 7.9e-63 212.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_8 PF01501.20 OIR58147.1 - 0.0019 17.8 1.9 0.45 10.0 0.4 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.6 OIR58147.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PelD_GGDEF PF16963.5 OIR58147.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 PelD GGDEF domain DnaJ PF00226.31 OIR58148.1 - 3.1e-27 94.5 5.4 8e-27 93.2 5.4 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 OIR58148.1 - 1e-23 83.9 6.4 3.1e-23 82.3 6.4 1.8 1 1 0 1 1 1 1 X-domain of DnaJ-containing RPT PF13446.6 OIR58148.1 - 0.00058 19.7 0.3 0.07 13.1 0.0 3.2 3 0 0 3 3 3 1 A repeated domain in UCH-protein HMG_box_2 PF09011.10 OIR58148.1 - 0.17 12.5 4.2 0.25 11.9 1.2 2.8 2 1 0 2 2 2 0 HMG-box domain PSII_Pbs27 PF13326.6 OIR58148.1 - 0.28 11.5 4.3 0.11 12.8 1.2 1.9 2 1 0 2 2 2 0 Photosystem II Pbs27 TPR_1 PF00515.28 OIR58148.1 - 0.96 9.4 5.4 19 5.3 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OIR58148.1 - 1 9.6 7.9 43 4.6 0.2 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Styelin PF17562.2 OIR58148.1 - 2.6 8.5 6.4 9.4 6.7 0.1 4.2 4 0 0 4 4 4 0 Styelin CHD5 PF04420.14 OIR58149.1 - 8.2e-08 32.3 1.7 1.3e-07 31.6 1.7 1.4 1 1 0 1 1 1 1 CHD5-like protein Pyrophosphatase PF00719.19 OIR58151.1 - 1.2e-53 181.3 0.2 1.5e-53 180.8 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase ABC_tran PF00005.27 OIR58152.1 - 0.0092 16.5 0.0 0.032 14.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SPC25 PF06703.11 OIR58152.1 - 5.1 6.9 6.6 23 4.8 0.1 2.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) IMD PF08397.11 OIR58153.1 - 0.15 11.4 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain 14-3-3 PF00244.20 OIR58155.1 - 1.7e-81 273.0 7.0 1.9e-81 272.8 7.0 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 OIR58155.1 - 0.035 14.1 0.5 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Flagellar protein FlaF GPI2 PF06432.11 OIR58157.1 - 8.4e-37 127.1 8.0 1.1e-36 126.8 8.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Pkinase PF00069.25 OIR58158.1 - 1.4e-57 195.0 0.0 1.7e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58158.1 - 2.1e-23 82.9 0.1 3.1e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR58158.1 - 3.1e-06 26.4 0.1 5.2e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OIR58158.1 - 1.6e-05 24.4 0.0 2.5e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 OIR58158.1 - 7e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR58158.1 - 0.0019 17.6 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OIR58158.1 - 0.076 11.8 0.0 0.31 9.8 0.0 1.8 1 1 1 2 2 2 0 Fungal protein kinase DEAD PF00270.29 OIR58159.1 - 8.5e-29 100.6 0.2 1.3e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58159.1 - 2e-20 73.2 0.0 1e-19 70.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58159.1 - 1.7e-07 31.4 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 OIR58159.1 - 0.077 12.8 0.1 0.72 9.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain MS_channel PF00924.18 OIR58160.1 - 1.1e-16 61.1 3.6 1.7e-16 60.4 3.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Thioredoxin_2 PF13098.6 OIR58161.1 - 0.07 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain TAFII55_N PF04658.13 OIR58162.1 - 2e-24 86.1 0.0 5e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 TAFII55 protein conserved region Sec3_C PF09763.9 OIR58163.1 - 2.9e-46 158.2 17.3 1.8e-29 102.7 4.2 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec3 Vps52 PF04129.12 OIR58163.1 - 5.6e-06 25.4 1.2 5.6e-06 25.4 1.2 1.7 2 0 0 2 2 2 1 Vps52 / Sac2 family ClpB_D2-small PF10431.9 OIR58163.1 - 0.012 15.7 2.2 1.1 9.4 0.8 2.9 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein YojJ PF10372.9 OIR58163.1 - 0.14 12.3 1.1 1.4 9.1 0.3 3.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF4201 PF13870.6 OIR58163.1 - 0.77 9.5 15.8 0.036 13.8 9.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 OIR58163.1 - 1.8 9.1 11.1 0.31 11.6 6.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 OIR58163.1 - 2.4 8.3 13.6 0.23 11.7 2.3 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 OIR58163.1 - 3.1 8.0 12.8 0.25 11.6 2.6 2.7 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 KxDL PF10241.9 OIR58163.1 - 6.5 7.1 19.1 0.11 12.8 3.6 4.2 5 0 0 5 5 5 0 Uncharacterized conserved protein Cpn60_TCP1 PF00118.24 OIR58164.1 - 7.3e-139 463.6 2.9 8.4e-139 463.4 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tropomyosin PF00261.20 OIR58165.1 - 0.00052 19.4 6.5 0.00075 18.9 6.5 1.2 1 0 0 1 1 1 1 Tropomyosin NPV_P10 PF05531.12 OIR58165.1 - 0.0056 17.1 1.3 2.2 8.8 0.7 2.2 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 OIR58165.1 - 0.02 15.6 1.3 0.02 15.6 1.3 1.9 1 1 1 2 2 2 0 Occludin homology domain Lebercilin PF15619.6 OIR58165.1 - 0.026 14.2 3.1 0.026 14.2 3.1 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4349 PF14257.6 OIR58165.1 - 0.04 13.4 5.9 1.2 8.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Baculo_F PF12259.8 OIR58165.1 - 0.051 12.1 0.3 0.079 11.5 0.3 1.3 1 0 0 1 1 1 0 Baculovirus F protein Baculo_PEP_C PF04513.12 OIR58165.1 - 0.12 12.4 1.9 0.23 11.5 0.7 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OIR58165.1 - 0.13 12.3 2.9 0.27 11.3 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 OIR58165.1 - 0.24 11.6 11.2 1.5 9.0 8.6 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 V-SNARE PF05008.15 OIR58165.1 - 0.24 11.8 8.3 6.7 7.2 2.9 2.8 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.11 OIR58165.1 - 0.38 9.6 6.8 0.51 9.2 6.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 OIR58165.1 - 0.46 11.0 7.5 0.6 10.6 7.5 1.2 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 OIR58165.1 - 0.48 10.7 1.9 3.5 7.9 1.9 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phlebovirus_NSM PF07246.11 OIR58165.1 - 0.65 9.3 6.4 0.96 8.8 6.4 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Seryl_tRNA_N PF02403.22 OIR58165.1 - 3.8 7.8 10.4 35 4.7 10.4 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Metallophos PF00149.28 OIR58166.1 - 1.3e-36 127.0 0.0 1.6e-36 126.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cytochrom_B562 PF07361.11 OIR58167.1 - 0.0096 16.6 0.1 0.0096 16.6 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b562 RmuC PF02646.16 OIR58167.1 - 0.041 13.0 7.7 0.4 9.8 0.1 2.2 2 0 0 2 2 2 0 RmuC family Mt_ATP-synt_D PF05873.12 OIR58167.1 - 0.047 13.5 2.3 0.073 12.9 0.0 2.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) bZIP_Maf PF03131.17 OIR58167.1 - 0.053 14.0 3.9 0.094 13.2 0.1 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor YabA PF06156.13 OIR58167.1 - 1.7 9.3 5.4 49 4.6 6.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA She9_MDM33 PF05546.11 OIR58167.1 - 1.7 8.4 6.5 15 5.4 5.1 2.6 1 1 2 3 3 3 0 She9 / Mdm33 family TMPIT PF07851.13 OIR58167.1 - 3.3 6.9 5.1 2.8 7.1 3.9 1.5 1 1 0 1 1 1 0 TMPIT-like protein ABC2_membrane PF01061.24 OIR58168.1 - 2.3e-08 33.7 14.6 4.1e-08 32.9 14.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter TolB_like PF15869.5 OIR58168.1 - 0.0052 16.1 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 TolB-like 6-blade propeller-like RNase_HII PF01351.18 OIR58169.1 - 5.6e-38 130.8 0.0 2.4e-34 118.9 0.0 2.5 2 1 1 3 3 3 2 Ribonuclease HII IMP2_N PF18590.1 OIR58170.1 - 0.15 12.6 0.1 0.31 11.6 0.1 1.5 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) N-terminal domain Tim17 PF02466.19 OIR58173.1 - 3.3e-11 43.5 7.7 4.4e-11 43.1 7.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family tRNA-synt_1 PF00133.22 OIR58174.1 - 2.2e-190 633.9 0.0 4.7e-189 629.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OIR58174.1 - 2.1e-29 102.4 0.2 4e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OIR58174.1 - 3.9e-14 52.2 0.0 4.8e-06 25.6 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OIR58174.1 - 2.4e-10 40.2 8.4 1.2e-08 34.7 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OIR58174.1 - 0.017 14.5 0.0 0.3 10.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain NinG PF05766.12 OIR58174.1 - 0.15 12.0 5.4 0.33 10.9 5.4 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein tRNA-synt_1b PF00579.25 OIR58174.1 - 1.4 8.1 5.0 1.7 7.9 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) NARP1 PF12569.8 OIR58174.1 - 1.9 7.3 10.4 3.5 6.4 10.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_22 PF13401.6 OIR58175.1 - 3e-07 30.8 0.1 5.7e-06 26.6 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 OIR58175.1 - 0.00035 21.0 0.0 0.0018 18.7 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OIR58175.1 - 0.00087 19.3 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OIR58175.1 - 0.059 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OIR58175.1 - 0.062 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OIR58175.1 - 0.067 13.6 0.0 0.2 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain CobU PF02283.16 OIR58175.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase CH PF00307.31 OIR58176.1 - 4.6e-25 87.9 0.1 5.2e-12 45.9 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CH_2 PF06294.11 OIR58176.1 - 0.005 16.9 0.1 1.8 8.8 0.0 3.7 3 1 1 4 4 4 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 OIR58176.1 - 0.0089 15.8 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain DUF1664 PF07889.12 OIR58176.1 - 0.41 10.7 19.6 0.097 12.7 0.6 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) HU-CCDC81_bac_2 PF18175.1 OIR58176.1 - 3.1 7.7 7.0 0.34 10.8 0.4 2.8 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 AAA PF00004.29 OIR58177.1 - 8.8e-41 139.4 0.1 2.3e-40 138.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OIR58177.1 - 1.5e-16 60.0 0.3 2.9e-16 59.1 0.3 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OIR58177.1 - 9.6e-12 44.5 0.5 2.2e-11 43.4 0.5 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OIR58177.1 - 9.3e-06 25.7 0.4 4.9e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OIR58177.1 - 2.4e-05 24.5 0.2 7.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OIR58177.1 - 3.5e-05 23.6 0.0 8.8e-05 22.3 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OIR58177.1 - 4e-05 24.1 0.1 0.0039 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OIR58177.1 - 0.00087 19.6 0.2 0.043 14.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OIR58177.1 - 0.0016 17.7 0.0 0.019 14.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 OIR58177.1 - 0.0036 17.4 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OIR58177.1 - 0.0041 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 OIR58177.1 - 0.0054 16.2 0.0 0.02 14.4 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 OIR58177.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OIR58177.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OIR58177.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 OIR58177.1 - 0.029 14.1 0.0 0.077 12.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 OIR58177.1 - 0.031 14.3 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OIR58177.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase JIP_LZII PF16471.5 OIR58177.1 - 0.094 12.9 2.1 0.19 11.9 2.1 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II AAA_11 PF13086.6 OIR58177.1 - 0.12 12.2 0.2 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OIR58177.1 - 0.13 11.9 0.2 0.46 10.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain ParA PF10609.9 OIR58178.1 - 2.3e-70 236.9 0.0 2.8e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OIR58178.1 - 1.8e-11 44.2 0.0 4.5e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OIR58178.1 - 4.2e-11 42.6 1.5 6.7e-10 38.6 0.5 2.3 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 OIR58178.1 - 2.1e-08 34.3 0.1 1.9e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 OIR58178.1 - 3.8e-05 23.1 1.3 0.00038 19.8 1.3 2.0 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 OIR58178.1 - 0.00036 20.1 0.1 0.00078 19.0 0.1 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 OIR58178.1 - 0.0018 18.1 0.4 0.055 13.3 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OIR58178.1 - 0.0025 17.4 0.7 0.0049 16.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OIR58178.1 - 0.0025 17.5 0.0 0.0096 15.6 0.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CLP1_P PF16575.5 OIR58178.1 - 0.0043 16.9 0.0 0.016 15.0 0.0 1.9 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 OIR58178.1 - 0.011 15.0 0.0 0.031 13.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 OIR58178.1 - 0.016 14.2 0.1 0.027 13.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 OIR58178.1 - 0.021 14.7 0.0 0.091 12.6 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase VirC1 PF07015.11 OIR58178.1 - 0.027 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein LpxK PF02606.14 OIR58178.1 - 0.027 13.6 0.6 0.053 12.6 0.2 1.6 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase Fer4_NifH PF00142.18 OIR58178.1 - 0.032 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 OIR58178.1 - 0.074 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 OIR58178.1 - 0.088 12.4 0.6 6 6.4 0.1 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 OIR58178.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF5628 PF18621.1 OIR58178.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5628) RhoGAP PF00620.27 OIR58179.1 - 7.8e-12 45.3 0.0 5.5e-10 39.3 0.0 2.5 1 1 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 OIR58179.1 - 4.1e-07 30.4 0.0 8.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain TMPIT PF07851.13 OIR58179.1 - 0.067 12.4 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein Josephin PF02099.17 OIR58180.1 - 1.4e-25 90.3 0.9 2.9e-25 89.3 0.9 1.5 1 1 0 1 1 1 1 Josephin Cupin_8 PF13621.6 OIR58183.1 - 0.1 12.3 0.4 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Cupin-like domain VAPB_antitox PF02697.14 OIR58183.1 - 0.28 12.0 11.3 0.47 11.3 0.0 4.2 4 0 0 4 4 4 0 Putative antitoxin FRB_dom PF08771.11 OIR58183.1 - 0.32 11.4 1.8 0.84 10.1 0.3 2.5 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Porin_3 PF01459.22 OIR58184.1 - 1e-32 113.7 0.2 1.3e-32 113.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin MiaE_2 PF13794.6 OIR58184.1 - 0.15 11.7 0.3 2.4 7.8 0.4 2.3 2 1 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like RNA_pol_Rpc34 PF05158.12 OIR58186.1 - 1.5e-51 175.8 0.7 8e-36 124.1 0.0 3.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit Mnd1 PF03962.15 OIR58186.1 - 0.002 18.4 0.0 0.17 12.2 0.0 2.6 2 0 0 2 2 2 1 Mnd1 HTH domain TrmB PF01978.19 OIR58186.1 - 0.026 14.4 0.2 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.20 OIR58186.1 - 0.11 12.8 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional regulator GWT1 PF06423.12 OIR58188.1 - 5.6e-07 29.8 10.6 4.1e-06 27.0 6.3 3.5 2 1 0 2 2 2 1 GWT1 BacA PF02673.18 OIR58188.1 - 0.024 14.3 4.6 0.63 9.7 0.0 3.3 2 1 2 4 4 4 0 Bacitracin resistance protein BacA Cation_ATPase_C PF00689.21 OIR58188.1 - 0.089 12.5 2.6 0.13 11.9 0.7 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Doppel PF11466.8 OIR58188.1 - 0.21 11.2 7.7 0.35 10.6 5.4 2.6 2 0 0 2 2 2 0 Prion-like protein Doppel EamA PF00892.20 OIR58188.1 - 1 9.5 14.1 0.15 12.2 2.0 3.7 3 1 1 4 4 4 0 EamA-like transporter family rve PF00665.26 OIR58189.1 - 3e-26 92.0 0.0 4.7e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OIR58189.1 - 0.00025 20.8 0.0 0.00065 19.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OIR58189.1 - 0.0049 17.1 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 DDE domain ubiquitin PF00240.23 OIR58190.1 - 2.7e-32 110.4 0.5 2.7e-32 110.4 0.5 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 OIR58190.1 - 2.4e-15 56.1 0.5 4.3e-15 55.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.19 OIR58190.1 - 2.5e-09 37.1 0.8 5.8e-09 36.0 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.6 OIR58190.1 - 0.00022 21.6 0.6 0.00085 19.7 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OIR58190.1 - 0.0013 18.8 0.5 0.0024 17.9 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OIR58190.1 - 0.0061 16.9 1.4 0.017 15.5 0.0 1.9 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 OIR58190.1 - 0.018 15.6 0.4 0.025 15.1 0.4 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 OIR58190.1 - 0.063 13.2 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Luteo_PO PF04662.13 OIR58191.1 - 0.037 13.7 0.3 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Luteovirus P0 protein HXXEE PF13787.6 OIR58191.1 - 0.1 13.4 1.7 0.59 11.0 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Glucos_trans_II PF14264.6 OIR58191.1 - 0.42 9.9 3.4 0.28 10.5 0.6 2.2 2 1 0 2 2 2 0 Glucosyl transferase GtrII Spore_YhaL PF14147.6 OIR58191.1 - 0.46 10.2 2.8 2 8.2 0.1 3.3 4 0 0 4 4 4 0 Sporulation protein YhaL Rad60-SLD PF11976.8 OIR58192.1 - 7e-17 61.0 0.0 8.3e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OIR58192.1 - 5.9e-07 29.2 0.0 7.2e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 OIR58192.1 - 0.011 15.9 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain Ufm1 PF03671.14 OIR58192.1 - 0.053 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Glycoprotein_B PF00606.18 OIR58192.1 - 0.13 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain B-block_TFIIIC PF04182.12 OIR58193.1 - 1e-09 38.4 0.0 3e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC PCEMA1 PF07418.11 OIR58193.1 - 0.1 12.1 5.6 0.16 11.5 0.4 2.3 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 HTH_26 PF13443.6 OIR58193.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HEAT PF02985.22 OIR58194.1 - 5.7e-10 38.6 7.0 0.0048 17.0 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat IBN_N PF03810.19 OIR58194.1 - 1.8e-07 30.9 0.3 3.2e-06 27.0 0.9 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 OIR58194.1 - 3.4e-07 30.6 3.2 0.0007 20.0 0.1 4.9 4 1 1 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 OIR58194.1 - 1.6e-06 28.4 6.0 0.064 13.6 0.1 4.9 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.7 OIR58194.1 - 0.003 17.6 0.0 0.058 13.4 0.0 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_10 PF12846.7 OIR58194.1 - 0.079 11.9 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain RICTOR_V PF14668.6 OIR58194.1 - 0.082 13.1 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Cohesin_HEAT PF12765.7 OIR58194.1 - 0.12 12.7 0.2 19 5.7 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ABC_tran PF00005.27 OIR58196.1 - 0.0039 17.7 0.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter FeoB_associated PF12669.7 OIR58196.1 - 0.54 10.7 2.1 1.6 9.2 0.0 3.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein RNase_P_Rpp14 PF01900.19 OIR58197.1 - 0.00084 19.5 0.0 0.0014 18.8 0.0 1.3 1 1 0 1 1 1 1 Rpp14/Pop5 family Rpr2 PF04032.16 OIR58198.1 - 0.0096 16.2 1.0 0.018 15.3 1.0 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain His_Phos_2 PF00328.22 OIR58199.1 - 1.2e-14 54.5 0.3 2.6e-10 40.2 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) UPF0016 PF01169.19 OIR58200.1 - 6.2e-37 125.8 17.0 2.9e-19 69.2 5.7 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.19 OIR58200.1 - 0.00049 19.8 7.3 0.014 15.0 6.9 2.1 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE MFS_MOT1 PF16983.5 OIR58200.1 - 3.6 8.0 11.3 0.64 10.4 2.8 2.2 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DEAD PF00270.29 OIR58201.1 - 3.6e-41 140.8 0.1 5.7e-41 140.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58201.1 - 3.1e-18 66.1 0.0 3e-17 63.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OIR58201.1 - 2.7e-09 37.1 0.0 5.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OIR58201.1 - 7.5e-08 32.6 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OIR58201.1 - 0.024 13.4 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain zf-B_box PF00643.24 OIR58202.1 - 1.3e-16 60.5 10.4 6.7e-08 32.6 1.4 2.5 2 0 0 2 2 2 2 B-box zinc finger Snf7 PF03357.21 OIR58202.1 - 0.077 12.6 4.1 0.13 11.8 4.1 1.3 1 0 0 1 1 1 0 Snf7 FlaC_arch PF05377.11 OIR58202.1 - 0.29 11.6 1.0 22 5.6 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CEBP_ZZ PF16366.5 OIR58202.1 - 3 8.1 14.1 3 8.2 2.1 2.9 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PCI PF01399.27 OIR58203.1 - 0.00047 20.6 0.9 0.011 16.2 0.0 3.0 3 0 0 3 3 3 1 PCI domain Nitrate_red_del PF02613.15 OIR58203.1 - 0.1 12.6 1.5 0.26 11.3 1.5 1.6 1 0 0 1 1 1 0 Nitrate reductase delta subunit LMP PF04778.12 OIR58203.1 - 0.11 12.4 1.6 0.76 9.7 0.0 2.6 3 0 0 3 3 3 0 LMP repeated region Pkinase PF00069.25 OIR58204.1 - 1.2e-28 100.2 0.0 1.4e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58204.1 - 2.7e-13 49.8 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR58204.1 - 3.1e-07 30.6 0.0 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OIR58204.1 - 0.0003 19.7 0.0 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PIP49_C PF12260.8 OIR58204.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Kinase-like PF14531.6 OIR58204.1 - 0.051 12.9 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Flavi_NS4A PF01350.17 OIR58205.1 - 0.99 9.3 4.1 1.3 8.9 0.2 2.9 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A DEAD PF00270.29 OIR58206.1 - 2.6e-28 99.0 0.1 4.9e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58206.1 - 1.2e-17 64.2 0.1 4.9e-17 62.3 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58206.1 - 1.8e-10 41.1 0.2 4.2e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OIR58206.1 - 0.00028 21.2 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_C_2 PF13307.6 OIR58206.1 - 0.00078 19.7 0.1 0.0022 18.2 0.0 1.7 2 1 0 2 2 2 1 Helicase C-terminal domain AAA_19 PF13245.6 OIR58206.1 - 0.0031 17.8 0.1 0.0071 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OIR58206.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T4SS-DNA_transf PF02534.14 OIR58206.1 - 0.12 11.2 0.0 4.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Trep_dent_lipo PF09710.10 OIR58206.1 - 0.15 11.0 0.1 0.38 9.6 0.0 1.6 2 0 0 2 2 2 0 Treponema clustered lipoprotein (Trep_dent_lipo) MutS_V PF00488.21 OIR58207.1 - 1.2e-43 149.3 0.0 3.6e-43 147.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OIR58207.1 - 5.5e-23 82.2 11.7 5.5e-23 82.2 11.7 2.0 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OIR58207.1 - 7.8e-06 26.1 2.0 7.8e-06 26.1 2.0 2.2 2 0 0 2 2 2 1 MutS family domain IV Med30 PF11315.8 OIR58207.1 - 1.2 9.4 7.0 0.45 10.7 3.6 2.0 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF4709 PF15821.5 OIR58207.1 - 1.4 9.3 7.0 0.36 11.1 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) Fe_hyd_lg_C PF02906.14 OIR58213.1 - 4.2e-27 95.4 0.1 5.5e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain ANAPC3 PF12895.7 OIR58216.1 - 1e-08 35.3 10.4 0.002 18.3 0.2 6.5 7 1 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OIR58216.1 - 2e-08 34.8 9.0 0.0013 19.4 1.1 5.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OIR58216.1 - 7.1e-07 28.9 17.1 0.041 14.0 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OIR58216.1 - 0.0001 22.2 0.0 0.92 9.9 0.0 4.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OIR58216.1 - 0.00035 20.3 7.4 0.079 12.8 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OIR58216.1 - 0.0019 18.9 16.2 5.2 8.2 0.0 7.4 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 OIR58216.1 - 0.013 16.0 10.1 5.3 7.6 1.0 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OIR58216.1 - 0.038 14.2 1.4 16 5.7 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OIR58216.1 - 0.092 12.8 0.2 9.4 6.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OIR58216.1 - 0.33 11.3 15.1 11 6.4 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OIR58216.1 - 0.59 10.1 5.3 17 5.5 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 OIR58218.1 - 2.2e-13 50.6 0.1 2.2e-10 40.8 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OIR58218.1 - 9.1e-07 28.5 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Tfb2 PF03849.14 OIR58219.1 - 1.4e-35 123.0 0.0 2e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OIR58219.1 - 5.4e-15 55.6 0.1 2.5e-14 53.4 0.1 2.1 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain UQ_con PF00179.26 OIR58220.1 - 4.3e-33 113.9 0.0 4.9e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OIR58220.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 RWD domain tRNA_synthFbeta PF17759.1 OIR58221.1 - 5.7e-43 146.8 0.0 8.1e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OIR58221.1 - 4.8e-22 78.0 0.0 1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 OIR58221.1 - 3.1e-15 56.2 0.0 2e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 OIR58221.1 - 1.6e-07 31.2 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain ANAPC4_WD40 PF12894.7 OIR58222.1 - 0.0042 17.3 0.0 0.045 14.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin PF00804.25 OIR58223.1 - 1.1e-12 48.1 14.0 1.4e-12 47.7 14.0 1.2 1 0 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 OIR58223.1 - 0.0012 19.2 11.3 0.0018 18.6 4.5 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Pox_J1 PF03338.15 OIR58223.1 - 0.017 15.0 1.1 0.047 13.5 1.1 1.8 1 1 0 1 1 1 0 Poxvirus J1 protein Baculo_PEP_C PF04513.12 OIR58223.1 - 0.35 10.9 3.4 0.97 9.5 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 OIR58223.1 - 2.7 5.8 12.8 1.3 6.9 10.2 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 OIR58223.1 - 8.8 6.9 13.2 2.2e+03 -0.8 13.2 2.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 NAP PF00956.18 OIR58224.1 - 7.6e-61 205.6 3.8 2.2e-55 187.8 0.2 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) ING PF12998.7 OIR58224.1 - 0.00031 21.3 0.2 0.00076 20.0 0.2 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Apolipoprotein PF01442.18 OIR58224.1 - 0.023 14.6 0.6 0.034 14.0 0.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain APG6_N PF17675.1 OIR58224.1 - 0.033 14.7 1.3 0.033 14.7 1.3 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region FAM177 PF14774.6 OIR58224.1 - 0.084 13.2 3.2 0.48 10.8 0.4 2.8 2 1 1 3 3 3 0 FAM177 family Syntaxin PF00804.25 OIR58225.1 - 1.5e-20 73.7 10.1 1.5e-20 73.7 10.1 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 OIR58225.1 - 4.8e-06 26.5 1.0 1.2e-05 25.2 1.0 1.7 1 0 0 1 1 1 1 SNARE domain Tweety PF04906.13 OIR58225.1 - 0.0066 15.2 1.4 0.0066 15.2 1.4 1.7 2 0 0 2 2 2 1 Tweety ThrE PF06738.12 OIR58225.1 - 0.015 14.6 0.1 0.035 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative threonine/serine exporter Trm56 PF01994.16 OIR58225.1 - 0.042 13.8 0.8 1.3 9.0 0.5 2.4 2 0 0 2 2 2 0 tRNA ribose 2'-O-methyltransferase, aTrm56 DUF2116 PF09889.9 OIR58225.1 - 0.052 13.5 0.4 0.052 13.5 0.4 3.4 2 1 1 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF677 PF05055.12 OIR58225.1 - 0.51 9.2 15.3 0.042 12.7 1.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF677) RNA_pol_I_A49 PF06870.12 OIR58226.1 - 0.024 13.5 0.1 0.052 12.4 0.0 1.5 1 1 0 1 1 1 0 A49-like RNA polymerase I associated factor zf-CCHC PF00098.23 OIR58227.1 - 1.8e-11 43.5 29.8 1.2e-06 28.3 2.4 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 OIR58227.1 - 6.5e-08 32.2 21.7 0.022 14.5 1.6 4.1 4 0 0 4 4 4 4 Zinc knuckle DUF1815 PF08844.10 OIR58227.1 - 0.67 10.0 6.7 2.5 8.1 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1815) IBR PF01485.21 OIR58227.1 - 4.8 7.5 24.7 5.7 7.2 1.4 3.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Sel1 PF08238.12 OIR58228.1 - 2.9e-84 275.6 49.9 3e-06 27.7 0.0 14.4 14 0 0 14 14 14 13 Sel1 repeat TPR_6 PF13174.6 OIR58228.1 - 5.8e-05 23.5 18.8 1.6 9.5 0.0 8.3 8 2 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR58228.1 - 0.067 13.8 0.2 0.067 13.8 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Rad51 PF08423.11 OIR58229.1 - 1.4e-17 63.8 0.3 2e-17 63.3 0.3 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OIR58229.1 - 9.7e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Robl_LC7 PF03259.17 OIR58229.1 - 0.036 13.8 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Roadblock/LC7 domain Glyco_hydro_3_C PF01915.22 OIR58229.1 - 0.22 11.5 0.0 3.1 7.7 0.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain zf-C3HC4_3 PF13920.6 OIR58230.1 - 4.2e-09 36.1 11.1 1e-08 34.9 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR58230.1 - 9.8e-07 28.6 11.8 2.1e-06 27.5 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR58230.1 - 7.8e-06 26.1 11.6 1.7e-05 25.1 11.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OIR58230.1 - 9.8e-06 25.3 11.3 1.9e-05 24.4 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR58230.1 - 1.3e-05 25.1 11.6 3.1e-05 23.8 11.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OIR58230.1 - 5e-05 23.1 10.0 0.00011 21.9 10.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OIR58230.1 - 0.0003 20.8 8.5 0.00065 19.7 8.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 OIR58230.1 - 0.0012 18.7 6.9 0.0025 17.6 6.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OIR58230.1 - 0.026 14.8 6.4 0.067 13.5 6.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 OIR58230.1 - 0.072 13.3 9.7 0.17 12.1 9.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.6 OIR58230.1 - 0.09 12.2 3.6 0.08 12.4 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.6 OIR58230.1 - 0.1 12.4 9.5 0.22 11.3 9.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TFIIS_C PF01096.18 OIR58231.1 - 1.7e-19 69.4 4.6 1.7e-19 69.4 4.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 OIR58231.1 - 2e-14 54.0 4.0 3.7e-14 53.2 4.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Ins_beta PF03488.14 OIR58231.1 - 0.017 15.1 0.8 0.035 14.1 0.0 2.0 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Complex1_49kDa PF00346.19 OIR58231.1 - 0.048 12.8 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SNAP PF14938.6 OIR58232.1 - 9.4e-60 202.4 4.6 1.1e-59 202.2 4.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 OIR58232.1 - 0.0001 22.1 17.0 0.51 10.6 1.6 6.5 4 1 4 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OIR58232.1 - 0.00016 21.9 6.2 0.01 16.1 0.5 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR58232.1 - 0.00016 22.2 8.7 0.12 13.0 4.5 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OIR58232.1 - 0.00062 19.6 1.4 4.9 7.4 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OIR58232.1 - 0.015 14.7 0.2 0.11 11.8 0.1 2.0 1 1 1 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 OIR58232.1 - 0.032 15.1 7.7 12 7.0 1.2 5.0 3 2 4 7 7 7 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 OIR58232.1 - 0.11 12.7 2.4 5.2 7.4 0.1 3.2 3 1 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 HHH_8 PF14716.6 OIR58232.1 - 0.26 11.7 6.5 0.55 10.6 0.9 2.8 3 0 0 3 3 2 0 Helix-hairpin-helix domain TPR_11 PF13414.6 OIR58232.1 - 0.3 10.8 3.3 44 3.9 0.1 4.2 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 OIR58232.1 - 0.81 10.1 12.1 14 6.2 0.0 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TIP49 PF06068.13 OIR58233.1 - 7.8e-121 403.6 0.6 1.1e-120 403.1 0.6 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OIR58233.1 - 5.5e-20 71.3 0.1 1.3e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OIR58233.1 - 1.8e-08 34.9 0.5 8.4e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OIR58233.1 - 9.1e-07 29.0 0.7 0.015 15.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OIR58233.1 - 5.9e-05 22.9 0.3 0.0011 18.8 0.1 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OIR58233.1 - 0.00019 21.9 0.3 0.00063 20.2 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 OIR58233.1 - 0.0002 20.8 1.1 0.027 13.8 0.5 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OIR58233.1 - 0.00073 19.3 0.2 0.71 9.6 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 OIR58233.1 - 0.0034 17.7 0.1 2.3 8.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_32 PF13654.6 OIR58233.1 - 0.0095 14.8 1.2 0.053 12.3 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OIR58233.1 - 0.011 16.1 2.1 0.18 12.1 2.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OIR58233.1 - 0.015 14.8 0.2 0.25 10.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 OIR58233.1 - 0.021 14.4 0.2 0.046 13.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OIR58233.1 - 0.03 14.3 0.1 0.074 13.1 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DnaB_C PF03796.15 OIR58233.1 - 0.065 12.6 1.4 0.19 11.0 0.4 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NACHT PF05729.12 OIR58233.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain XRN_M PF17846.1 OIR58234.1 - 1.5e-101 340.5 5.3 5.1e-68 230.0 1.7 2.1 1 1 1 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 OIR58234.1 - 3.4e-84 282.1 0.0 6.3e-82 274.6 0.0 2.7 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 OIR58234.1 - 0.29 11.3 4.7 0.59 10.3 4.7 1.5 1 0 0 1 1 1 0 Zinc knuckle GRAM PF02893.20 OIR58235.1 - 3.1e-16 59.3 1.2 9.3e-16 57.7 1.2 1.8 1 0 0 1 1 1 1 GRAM domain Metal_resist PF13801.6 OIR58235.1 - 0.062 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Snf7 PF03357.21 OIR58236.1 - 1.5e-30 106.1 14.8 1.8e-30 105.8 14.8 1.1 1 0 0 1 1 1 1 Snf7 TFCD_C PF12612.8 OIR58236.1 - 0.00021 21.2 0.1 0.00022 21.1 0.1 1.2 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal SOGA PF11365.8 OIR58236.1 - 0.29 12.3 4.6 1 10.5 4.6 2.0 1 1 0 1 1 1 0 Protein SOGA HECT_2 PF09814.9 OIR58237.1 - 3.1e-24 85.6 0.2 4.2e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding CDtoxinA PF03498.14 OIR58237.1 - 0.12 12.0 0.2 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Gti1_Pac2 PF09729.9 OIR58238.1 - 1.2e-42 146.0 1.3 2.1e-42 145.2 0.1 2.0 2 1 0 2 2 2 1 Gti1/Pac2 family Syntaxin PF00804.25 OIR58239.1 - 2e-17 63.6 16.2 2e-17 63.6 16.2 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 OIR58239.1 - 0.00013 21.8 0.5 0.00048 20.1 0.0 2.2 2 0 0 2 2 2 1 SNARE domain HisKA_3 PF07730.13 OIR58239.1 - 0.0028 18.1 4.4 0.023 15.2 0.6 3.1 3 0 0 3 3 3 1 Histidine kinase Ribonuc_L-PSP PF01042.21 OIR58239.1 - 0.12 12.4 2.9 1.8 8.6 0.2 2.8 4 0 0 4 4 4 0 Endoribonuclease L-PSP COG2 PF06148.11 OIR58239.1 - 0.69 10.0 7.7 8 6.6 1.8 2.8 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CAF1 PF04857.20 OIR58239.1 - 0.87 8.7 8.5 1.7 7.7 8.5 1.7 1 1 0 1 1 1 0 CAF1 family ribonuclease DUF16 PF01519.16 OIR58239.1 - 2.5 8.6 14.9 1.3 9.5 1.9 2.9 2 2 0 2 2 2 0 Protein of unknown function DUF16 Cauli_DNA-bind PF03310.13 OIR58239.1 - 2.6 8.1 10.7 0.24 11.5 1.5 2.7 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein Phage_Gp19 PF09355.10 OIR58239.1 - 2.8 8.4 11.1 0.76 10.2 0.6 3.7 5 0 0 5 5 5 0 Phage protein Gp19/Gp15/Gp42 DUF4446 PF14584.6 OIR58239.1 - 3.4 7.6 13.6 4 7.4 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Syntaxin_2 PF14523.6 OIR58239.1 - 5 7.6 16.4 9.1 6.7 8.7 3.5 2 2 1 3 3 3 0 Syntaxin-like protein DUF2379 PF09543.10 OIR58239.1 - 6.9 6.9 8.8 5.5 7.2 0.2 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2379) SlyX PF04102.12 OIR58239.1 - 9.3 7.0 12.0 14 6.3 0.2 3.7 2 1 1 3 3 3 0 SlyX DUF948 PF06103.11 OIR58239.1 - 9.4 6.6 15.2 8.7 6.7 0.5 4.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) UQ_con PF00179.26 OIR58240.1 - 2.4e-42 143.9 0.0 2.7e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR58240.1 - 7.8e-06 25.6 0.0 1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 OIR58240.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 OIR58240.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain UQ_con PF00179.26 OIR58241.1 - 6.3e-45 152.3 0.0 1.2e-44 151.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR58241.1 - 2.1e-07 30.7 0.0 2.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OIR58241.1 - 0.012 15.9 0.1 0.024 14.9 0.1 1.7 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 OIR58241.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 OIR58241.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain Bax1-I PF01027.20 OIR58242.1 - 8.8e-21 74.7 27.5 1e-20 74.5 27.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Rcd1 PF04078.13 OIR58243.1 - 1.7e-62 211.1 3.5 2e-62 210.8 3.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cas_NE0113 PF09623.10 OIR58243.1 - 0.096 12.4 0.7 0.16 11.6 0.7 1.3 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) ELFV_dehydrog PF00208.21 OIR58244.1 - 4.5e-48 164.1 0.0 7.7e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OIR58244.1 - 4e-30 104.2 0.0 2e-21 75.4 0.0 2.9 2 1 1 3 3 3 3 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 OIR58244.1 - 0.027 14.4 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ribosomal_L7Ae PF01248.26 OIR58245.1 - 2e-15 56.3 0.1 2.9e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OIR58245.1 - 0.0076 16.3 0.1 0.0093 16.0 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Bax1-I PF01027.20 OIR58246.1 - 2.1e-10 40.8 19.4 2.4e-10 40.6 19.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Mem_trans PF03547.18 OIR58246.1 - 0.034 12.5 3.4 0.064 11.6 3.4 1.6 1 1 0 1 1 1 0 Membrane transport protein DUF2070 PF09843.9 OIR58246.1 - 2.4 6.3 22.8 1.3 7.3 21.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) YfhO PF09586.10 OIR58246.1 - 3.1 5.9 17.7 0.27 9.4 10.1 1.9 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Myc_target_1 PF15179.6 OIR58246.1 - 4 7.3 4.4 1.4 8.7 1.5 1.7 2 0 0 2 2 2 0 Myc target protein 1 2TM PF13239.6 OIR58246.1 - 4.8 7.6 8.8 0.96 9.8 0.2 3.2 2 1 0 2 2 2 0 2TM domain DUF3754 PF12576.8 OIR58246.1 - 5.8 6.9 7.8 41 4.1 4.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Ribosomal_S17 PF00366.20 OIR58247.1 - 1.4e-28 98.8 3.5 2e-28 98.3 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 OIR58247.1 - 2e-25 88.9 0.7 2e-25 88.9 0.7 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal NMT PF01233.19 OIR58249.1 - 3.2e-47 160.3 0.0 5.7e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 OIR58249.1 - 4.6e-35 121.0 0.0 6.5e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 OIR58249.1 - 7.7e-07 29.4 0.2 2.2e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OIR58249.1 - 6.7e-05 23.0 0.0 0.00019 21.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OIR58249.1 - 0.056 13.4 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR58249.1 - 0.062 13.7 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.26 OIR58250.1 - 8.1e-45 151.9 0.0 1.3e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR58250.1 - 0.00011 21.9 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OIR58250.1 - 0.0012 19.1 0.2 0.0018 18.6 0.2 1.5 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 OIR58250.1 - 0.0034 17.0 0.1 0.0073 16.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 OIR58250.1 - 0.044 13.6 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF4169 PF13770.6 OIR58250.1 - 0.053 13.8 0.2 0.053 13.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) UQ_con PF00179.26 OIR58252.1 - 1.4e-38 131.7 0.0 2.9e-38 130.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OIR58252.1 - 0.077 13.3 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 RWD domain PqqD PF05402.12 OIR58253.1 - 0.069 13.5 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) UQ_con PF00179.26 OIR58254.1 - 1.9e-39 134.5 0.0 2.4e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OIR58254.1 - 0.0039 17.5 0.1 0.0057 16.9 0.1 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 OIR58254.1 - 0.029 14.1 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 OIR58254.1 - 0.045 13.4 0.0 0.072 12.7 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 OIR58254.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 UEV domain UQ_con PF00179.26 OIR58255.1 - 2.1e-37 127.9 0.0 2.7e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mem_trans PF03547.18 OIR58256.1 - 0.023 13.1 4.9 0.039 12.4 4.6 1.7 1 1 0 1 1 1 0 Membrane transport protein DUF2070 PF09843.9 OIR58256.1 - 0.13 10.5 17.5 0.16 10.2 17.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) YfhO PF09586.10 OIR58256.1 - 1.6 6.9 12.0 2.8 6.1 12.0 1.5 1 1 0 1 1 1 0 Bacterial membrane protein YfhO GPI2 PF06432.11 OIR58256.1 - 2.9 7.3 8.9 6 6.2 8.9 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Arv1 PF04161.13 OIR58257.1 - 3.2e-29 102.6 1.9 5.3e-29 101.9 1.9 1.3 1 0 0 1 1 1 1 Arv1-like family DUF1700 PF08006.11 OIR58257.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) Rhodanese_C PF12368.8 OIR58257.1 - 0.23 11.8 1.5 3.6 8.0 1.5 2.4 1 1 0 1 1 1 0 Rhodanase C-terminal DZR PF12773.7 OIR58257.1 - 0.39 10.8 2.2 0.84 9.7 2.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 OIR58257.1 - 1.1 8.8 4.1 10 5.7 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Det1 PF09737.9 OIR58258.1 - 8.3e-35 120.6 1.3 3.1e-34 118.7 1.3 1.8 1 1 0 1 1 1 1 De-etiolated protein 1 Det1 EF-hand_7 PF13499.6 OIR58259.1 - 3.9e-09 36.8 0.5 1.4e-08 35.1 0.5 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OIR58259.1 - 4.5e-08 32.4 0.9 0.0074 16.1 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OIR58259.1 - 1.9e-07 30.1 2.2 0.012 15.1 0.7 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OIR58259.1 - 6.9e-07 29.0 4.4 0.00044 20.1 1.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 OIR58259.1 - 5.7e-06 25.6 4.3 0.0047 16.4 0.7 2.5 2 0 0 2 2 2 2 EF hand Bax1-I PF01027.20 OIR58260.1 - 1.8e-16 60.6 23.3 2.2e-16 60.3 23.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5090 PF17009.5 OIR58260.1 - 0.63 10.0 16.3 0.034 14.1 9.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) SHR3_chaperone PF08229.11 OIR58260.1 - 0.95 8.4 6.7 0.29 10.1 3.8 1.7 2 0 0 2 2 2 0 ER membrane protein SH3 S_4TM PF18159.1 OIR58260.1 - 4.7 6.4 7.0 0.75 9.0 1.9 2.1 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF1129 PF06570.11 OIR58260.1 - 5.4 6.4 7.0 0.67 9.4 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) PAS_4 PF08448.10 OIR58261.1 - 0.091 13.0 0.1 0.17 12.1 0.0 1.4 2 0 0 2 2 2 0 PAS fold RPN1_RPN2_N PF17781.1 OIR58262.1 - 1.2e-68 231.8 0.0 1.6e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OIR58262.1 - 2e-23 82.1 0.1 4.3e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 OIR58262.1 - 2.6e-14 53.4 3.6 0.00069 20.0 0.0 5.9 5 1 1 6 6 6 4 HEAT repeats PC_rep PF01851.22 OIR58262.1 - 3.7e-13 49.2 14.2 0.0033 17.8 0.0 8.5 9 1 1 10 10 10 3 Proteasome/cyclosome repeat HEAT PF02985.22 OIR58262.1 - 0.00019 21.4 0.3 40 4.8 0.0 6.0 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.7 OIR58262.1 - 0.025 14.6 0.1 16 5.5 0.0 3.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RMI1_N PF08585.12 OIR58263.1 - 2.3e-08 34.1 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RecQ mediated genome instability protein SRP54 PF00448.22 OIR58264.1 - 1.6e-47 161.7 0.2 3.4e-47 160.6 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OIR58264.1 - 1.7e-06 28.2 3.3 2.2e-06 27.8 0.5 2.5 2 1 0 2 2 2 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 OIR58264.1 - 1.8e-05 24.8 0.0 4.5e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 OIR58264.1 - 2.8e-05 24.6 0.2 0.09 13.2 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 OIR58264.1 - 8.8e-05 21.6 0.2 0.00038 19.5 0.2 2.0 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 OIR58264.1 - 0.00015 21.9 0.0 0.00076 19.5 0.0 2.2 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OIR58264.1 - 0.00022 21.0 0.1 0.00043 20.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OIR58264.1 - 0.0003 21.1 0.0 0.052 13.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OIR58264.1 - 0.0022 17.8 0.0 0.0078 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OIR58264.1 - 0.0034 17.7 0.1 0.01 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain Fer4_NifH PF00142.18 OIR58264.1 - 0.0036 16.8 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 OIR58264.1 - 0.005 16.1 0.0 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase NTPase_1 PF03266.15 OIR58264.1 - 0.006 16.5 3.6 0.07 13.0 0.6 3.0 2 1 0 2 2 2 1 NTPase AAA_31 PF13614.6 OIR58264.1 - 0.0097 15.8 0.1 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain KdpD PF02702.17 OIR58264.1 - 0.021 14.3 0.1 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain TniB PF05621.11 OIR58264.1 - 0.023 14.1 0.0 17 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_17 PF13207.6 OIR58264.1 - 0.023 15.1 2.1 0.49 10.8 0.2 3.5 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OIR58264.1 - 0.025 14.6 0.9 0.13 12.3 0.3 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase PIN_2 PF10130.9 OIR58264.1 - 0.057 13.7 0.3 0.1 12.8 0.3 1.4 1 0 0 1 1 1 0 PIN domain CobA_CobO_BtuR PF02572.15 OIR58264.1 - 0.061 13.6 0.2 0.25 11.6 0.0 2.1 2 1 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP ZT_dimer PF16916.5 OIR58264.1 - 0.065 13.4 0.1 10 6.4 0.0 2.7 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter PduV-EutP PF10662.9 OIR58264.1 - 0.065 13.0 0.1 4.4 7.1 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 OIR58264.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OIR58264.1 - 0.071 13.6 0.1 0.47 11.0 0.0 2.2 1 1 1 2 2 2 0 ABC transporter AAA_33 PF13671.6 OIR58264.1 - 0.072 13.2 0.1 0.19 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 OIR58264.1 - 0.094 12.2 0.1 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family CLP1_P PF16575.5 OIR58264.1 - 0.15 11.9 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 OIR58264.1 - 0.15 11.9 0.0 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 NACHT domain RuBisCO_small PF00101.20 OIR58264.1 - 0.15 12.0 0.1 13 5.9 0.0 2.8 2 1 1 3 3 3 0 Ribulose bisphosphate carboxylase, small chain Peptidase_M1 PF01433.20 OIR58265.1 - 5.7e-85 284.3 0.3 8.9e-85 283.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 OIR58265.1 - 3.5e-63 214.0 3.2 6.1e-63 213.3 3.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 OIR58265.1 - 1.2e-46 159.3 0.1 3.7e-45 154.4 0.0 2.5 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain Acetyltransf_13 PF13880.6 OIR58265.1 - 0.045 13.7 0.4 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase DnaJ PF00226.31 OIR58266.1 - 8.4e-15 54.7 0.0 2.1e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 OIR58266.1 - 2.1e-10 40.6 1.6 1.2e-06 28.6 0.4 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR58266.1 - 0.00046 20.4 0.3 0.01 16.1 0.3 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.25 OIR58267.1 - 4.4e-46 157.4 0.0 1.1e-42 146.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58267.1 - 3.3e-18 65.9 0.0 6.5e-14 51.8 0.0 3.9 2 1 0 2 2 2 2 Protein tyrosine kinase PolyA_pol_RNAbd PF12627.7 OIR58267.1 - 0.099 12.4 0.0 29 4.5 0.1 3.3 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A ERCC3_RAD25_C PF16203.5 OIR58268.1 - 1.5e-103 345.3 0.0 2.5e-103 344.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OIR58268.1 - 7.7e-29 100.4 0.0 1.5e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58268.1 - 1.5e-17 64.1 0.0 3.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OIR58268.1 - 9.9e-12 45.2 0.3 3.2e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OIR58268.1 - 1.1e-10 40.7 0.1 1.7e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 OIR58268.1 - 8.5e-06 25.6 0.1 1.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase GLTSCR1 PF15249.6 OIR58269.1 - 7.1e-12 45.7 0.6 7.1e-12 45.7 0.6 2.0 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein Hydrolase_4 PF12146.8 OIR58269.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 O-FucT PF10250.9 OIR58271.1 - 3e-12 46.9 0.2 5.3e-11 42.8 0.2 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MIR PF02815.19 OIR58272.1 - 2.6e-24 86.1 0.6 3.9e-24 85.5 0.6 1.2 1 0 0 1 1 1 1 MIR domain PMT PF02366.18 OIR58272.1 - 1.2e-21 77.5 12.1 2.4e-21 76.4 12.1 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OIR58272.1 - 2.5e-14 53.4 0.3 2.5e-14 53.4 0.3 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 OIR58272.1 - 0.013 15.8 7.4 0.013 15.8 7.4 2.5 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase US6 PF17616.2 OIR58272.1 - 0.025 14.5 1.4 0.6 10.0 0.1 3.1 4 0 0 4 4 4 0 Viral unique short region 6 DNA_mis_repair PF01119.19 OIR58274.1 - 3.3e-20 72.0 0.0 6e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 OIR58274.1 - 9.4e-19 67.6 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OIR58274.1 - 1.9e-10 40.7 0.3 3.4e-10 39.9 0.3 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OIR58274.1 - 4.6e-06 27.1 0.4 1.5e-05 25.4 0.3 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tub PF01167.18 OIR58275.1 - 1.4e-35 123.2 0.7 9.2e-29 100.9 0.1 2.1 1 1 1 2 2 2 2 Tub family UQ_con PF00179.26 OIR58276.1 - 1e-35 122.4 0.0 1.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OIR58276.1 - 0.089 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Spc7 PF08317.11 OIR58277.1 - 3.5e-33 114.8 4.8 5.6e-33 114.1 4.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2533 PF10752.9 OIR58277.1 - 0.0062 17.0 5.7 0.065 13.7 0.6 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2533) BRE1 PF08647.11 OIR58277.1 - 0.012 15.6 11.2 0.028 14.5 6.1 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 OIR58277.1 - 0.049 13.8 4.9 0.14 12.3 4.0 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PM0188 PF11477.8 OIR58277.1 - 0.098 11.8 0.5 0.16 11.1 0.5 1.2 1 0 0 1 1 1 0 Sialyltransferase PMO188 DUF16 PF01519.16 OIR58277.1 - 0.55 10.8 13.1 0.25 11.8 3.6 3.8 3 1 1 4 4 4 0 Protein of unknown function DUF16 DUF724 PF05266.14 OIR58277.1 - 0.57 10.0 13.0 1.7 8.4 13.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TSC22 PF01166.18 OIR58277.1 - 0.77 10.1 4.8 2.4 8.5 4.8 1.9 1 0 0 1 1 1 0 TSC-22/dip/bun family GLTP PF08718.11 OIR58277.1 - 1 9.6 4.1 2.3 8.5 2.8 2.1 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) Sec34 PF04136.15 OIR58277.1 - 1.3 8.9 13.0 0.96 9.3 0.1 3.5 3 1 1 4 4 4 0 Sec34-like family ADIP PF11559.8 OIR58277.1 - 1.7 8.7 13.8 1.3 9.1 10.6 2.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 OIR58277.1 - 3.4 8.2 19.7 0.39 11.3 14.5 2.1 2 0 0 2 2 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 OIR58277.1 - 5.1 6.6 10.4 7.6 6.0 9.3 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 OIR58277.1 - 6.8 7.0 19.9 2.2 8.5 9.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Kinesin PF00225.23 OIR58278.1 - 2e-104 349.1 0.0 3.7e-104 348.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OIR58278.1 - 2.1e-27 95.9 0.0 1.1e-26 93.6 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 OIR58278.1 - 2 8.7 8.0 11 6.3 0.1 3.8 4 0 0 4 4 4 0 AAA domain HALZ PF02183.18 OIR58278.1 - 3.9 7.8 16.1 0.44 10.8 1.3 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper PK PF00224.21 OIR58279.1 - 9.8e-147 488.4 4.3 1.2e-146 488.1 4.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OIR58279.1 - 2.3e-23 82.6 1.3 1.5e-21 76.8 0.0 3.3 3 1 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OIR58279.1 - 0.00037 19.7 1.6 0.00091 18.4 1.1 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OIR58279.1 - 0.058 12.4 1.0 0.19 10.7 0.0 2.2 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 OIR58279.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) CENP-F_N PF10481.9 OIR58280.1 - 0.011 15.4 3.1 0.011 15.4 3.1 2.0 1 1 1 2 2 2 0 Cenp-F N-terminal domain DUF1664 PF07889.12 OIR58280.1 - 0.24 11.4 1.3 0.5 10.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 OIR58280.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.9 3 1 0 3 3 3 0 Septum formation initiator WD40_alt PF14077.6 OIR58280.1 - 1.4 8.8 6.1 2.6 8.0 0.5 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF4140 PF13600.6 OIR58280.1 - 8.2 6.9 9.1 2.4 8.7 0.3 3.0 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) IF4E PF01652.18 OIR58281.1 - 1.1e-22 80.5 0.1 1.5e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PAP2 PF01569.21 OIR58282.1 - 3.6e-15 55.9 1.0 3.6e-15 55.9 1.0 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OIR58282.1 - 1.9e-05 24.5 4.6 0.002 17.9 0.5 2.9 1 1 1 2 2 2 2 PAP2 superfamily Arteri_env PF01606.16 OIR58282.1 - 0.049 13.5 0.4 9.5 6.0 0.1 2.2 1 1 1 2 2 2 0 Arterivirus envelope protein PAP2_C PF14360.6 OIR58282.1 - 0.8 10.3 4.3 2.4 8.8 0.0 2.9 3 1 0 3 3 3 0 PAP2 superfamily C-terminal Ribosomal_S4e PF00900.20 OIR58283.1 - 4.5e-31 106.6 0.1 4.5e-31 106.6 0.1 2.1 3 0 0 3 3 3 1 Ribosomal family S4e RS4NT PF08071.12 OIR58283.1 - 1.9e-15 56.6 4.8 4.5e-15 55.5 4.8 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 OIR58283.1 - 2.8e-13 49.3 1.4 4.6e-13 48.6 0.3 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 OIR58283.1 - 6.8e-07 28.9 0.1 1.5e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 OIR58283.1 - 0.0035 17.2 2.4 0.0035 17.2 2.4 3.4 3 2 2 5 5 5 1 KOW motif Sec23_trunk PF04811.15 OIR58284.1 - 4.1e-30 105.1 0.0 1.2e-29 103.6 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OIR58284.1 - 2.1e-18 66.8 0.0 4.7e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OIR58284.1 - 7e-15 54.8 1.3 1.7e-14 53.6 1.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OIR58284.1 - 0.00026 20.8 0.0 0.00059 19.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 OIR58284.1 - 0.0039 17.8 0.0 5.5 7.7 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain Sec23_helical PF04815.15 OIR58284.1 - 0.0048 16.7 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain VWA PF00092.28 OIR58284.1 - 0.019 15.2 0.1 0.34 11.1 0.1 2.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Vps36-NZF-N PF16988.5 OIR58284.1 - 0.078 12.4 0.4 0.17 11.3 0.4 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Snf7 PF03357.21 OIR58286.1 - 3.1e-30 105.1 18.7 3.6e-30 104.8 18.7 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 OIR58286.1 - 0.00016 22.0 0.6 0.059 13.8 0.1 2.4 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 OIR58286.1 - 0.021 15.1 13.3 0.34 11.1 0.3 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CLZ PF16526.5 OIR58286.1 - 0.049 14.0 1.4 0.049 14.0 1.4 3.9 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF98 PF01947.16 OIR58286.1 - 0.056 13.4 0.1 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase Emaravirus_P4 PF16505.5 OIR58286.1 - 0.13 11.2 3.2 0.06 12.4 1.2 1.4 2 0 0 2 2 2 0 P4 movement protein of Emaravirus, and the 30K superfamily Uds1 PF15456.6 OIR58286.1 - 0.15 12.3 11.4 0.65 10.2 0.2 2.5 2 1 0 2 2 2 0 Up-regulated During Septation XhlA PF10779.9 OIR58286.1 - 0.17 12.1 0.6 0.17 12.1 0.6 3.1 3 1 1 4 4 4 0 Haemolysin XhlA Spc7 PF08317.11 OIR58286.1 - 0.64 8.9 18.6 0.88 8.4 17.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 OIR58286.1 - 0.85 8.2 15.9 0.63 8.6 10.5 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A HemX PF04375.14 OIR58286.1 - 0.91 8.7 9.5 2.1 7.6 0.2 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2730 PF10805.8 OIR58286.1 - 1.2 9.3 10.8 0.28 11.3 1.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Occludin_ELL PF07303.13 OIR58286.1 - 1.3 9.8 7.4 2 9.2 1.0 2.7 1 1 2 3 3 3 0 Occludin homology domain SlyX PF04102.12 OIR58286.1 - 1.5 9.5 0.0 1.5 9.5 0.0 3.5 3 1 0 3 3 3 0 SlyX FliD_N PF02465.18 OIR58286.1 - 3.8 8.3 7.9 5.1 7.8 3.6 2.5 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF848 PF05852.11 OIR58286.1 - 4.9 7.3 11.0 1.6 8.9 5.5 2.2 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) USP8_interact PF08941.10 OIR58286.1 - 5.2 6.8 7.0 5.7 6.7 0.5 2.3 1 1 1 2 2 2 0 USP8 interacting Borrelia_P83 PF05262.11 OIR58286.1 - 6.7 5.1 13.9 8.7 4.7 13.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 OIR58286.1 - 7.8 5.7 9.2 10 5.4 7.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 OIR58286.1 - 9.4 6.3 15.3 78 3.3 5.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 OIR58286.1 - 9.8 6.2 19.3 8.8 6.4 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SMC_N PF02463.19 OIR58287.1 - 3.9e-30 104.9 5.9 1.2e-29 103.4 5.9 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OIR58287.1 - 1.1e-11 45.6 37.9 1.1e-11 45.6 37.9 5.9 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 OIR58287.1 - 1.5e-08 34.8 15.0 1.5e-08 34.8 15.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OIR58287.1 - 2.2e-05 24.1 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OIR58287.1 - 0.014 15.2 0.0 0.014 15.2 0.0 4.1 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OIR58287.1 - 0.2 11.2 2.1 0.36 10.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain Sec20 PF03908.13 OIR58287.1 - 0.52 10.3 5.8 3.4 7.6 1.3 3.3 2 0 0 2 2 2 0 Sec20 DUF3573 PF12097.8 OIR58287.1 - 0.68 8.7 3.6 0.28 10.0 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) AAA_33 PF13671.6 OIR58287.1 - 0.99 9.6 6.7 7.5 6.7 0.4 3.9 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 OIR58287.1 - 2.8 7.8 9.5 2.4 8.0 0.1 3.5 3 1 1 4 4 4 0 Rad17 P-loop domain IF-2B PF01008.17 OIR58288.1 - 1.4e-47 162.2 0.1 1.8e-47 161.9 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 OIR58288.1 - 0.0085 16.0 0.0 0.69 9.8 0.0 2.4 2 0 0 2 2 2 2 DeoR C terminal sensor domain Helo_like_N PF17111.5 OIR58289.1 - 0.4 10.0 6.6 0.12 11.7 1.6 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins GATA PF00320.27 OIR58290.1 - 2.4e-16 59.0 14.9 4.7e-16 58.1 2.7 2.8 3 0 0 3 3 3 2 GATA zinc finger Rpr2 PF04032.16 OIR58290.1 - 0.00017 21.8 7.1 0.0053 17.0 3.2 2.3 1 1 1 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.12 OIR58290.1 - 0.00063 19.2 0.3 0.00063 19.2 0.3 2.5 2 1 0 2 2 2 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 OIR58290.1 - 0.021 14.7 7.7 0.028 14.3 1.3 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 OIR58290.1 - 0.085 12.9 10.6 0.48 10.5 2.1 2.7 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OIR58290.1 - 0.088 12.9 3.5 0.11 12.7 0.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-B_box PF00643.24 OIR58290.1 - 0.15 12.2 10.6 0.49 10.6 1.3 2.9 2 1 0 2 2 2 0 B-box zinc finger Cytochrom_c3_2 PF14537.6 OIR58290.1 - 0.72 10.4 6.8 1.5 9.4 6.8 1.6 1 1 0 1 1 1 0 Cytochrome c3 zf-ribbon_3 PF13248.6 OIR58290.1 - 1.6 8.3 11.4 0.33 10.4 0.3 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Fer4_2 PF12797.7 OIR58290.1 - 1.6 9.0 6.9 62 4.0 0.2 3.5 3 0 0 3 3 3 0 4Fe-4S binding domain zf-RING_5 PF14634.6 OIR58290.1 - 4.6 7.3 11.5 0.66 10.0 2.3 2.8 2 1 0 2 2 2 0 zinc-RING finger domain WD40_like PF17005.5 OIR58291.1 - 0.00034 20.1 0.5 0.81 9.0 0.0 3.0 1 1 2 3 3 3 3 WD40-like domain Vfa1 PF08432.10 OIR58291.1 - 0.017 15.5 0.2 0.027 14.8 0.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_S14 PF00253.21 OIR58292.1 - 4.8e-13 48.7 4.3 5.2e-13 48.5 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 OIR58292.1 - 0.036 14.0 0.3 0.047 13.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) GCD14 PF08704.10 OIR58293.1 - 2.3e-60 204.4 0.7 3e-59 200.7 0.1 2.0 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 OIR58293.1 - 1e-05 25.2 0.3 3.4e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 OIR58293.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OIR58293.1 - 0.0013 18.6 0.0 0.0034 17.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OIR58293.1 - 0.0059 16.3 0.0 0.036 13.7 0.0 1.9 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 OIR58293.1 - 0.046 14.7 0.1 0.1 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Phage_holin_5_1 PF06946.11 OIR58293.1 - 0.08 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 RrnaAD PF00398.20 OIR58293.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PI3_PI4_kinase PF00454.27 OIR58294.1 - 7.7e-39 134.0 0.2 1e-36 127.0 0.2 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OIR58294.1 - 7e-14 51.6 0.2 2.9e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CNOT11 PF10155.9 OIR58294.1 - 0.012 15.8 2.8 0.13 12.4 1.2 3.1 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Scm3 PF10384.9 OIR58295.1 - 0.00035 20.3 1.1 0.00048 19.8 0.3 1.7 2 0 0 2 2 2 1 Centromere protein Scm3 EF-hand_like PF09279.11 OIR58295.1 - 0.054 14.0 0.1 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Rav1p_C PF12234.8 OIR58296.1 - 5.2e-23 81.3 2.3 1.2e-22 80.2 2.3 1.5 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40_like PF17005.5 OIR58296.1 - 0.01 15.2 4.5 0.081 12.2 0.0 3.6 3 1 1 4 4 4 0 WD40-like domain ANAPC3 PF12895.7 OIR58296.1 - 0.07 13.4 0.3 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SWIB PF02201.18 OIR58298.1 - 2.8e-14 52.8 0.0 4.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain NMD3 PF04981.13 OIR58299.1 - 1.9e-58 197.8 5.5 2.7e-58 197.3 5.5 1.2 1 0 0 1 1 1 1 NMD3 family NinF PF05810.12 OIR58299.1 - 0.24 11.3 1.9 0.35 10.8 0.3 2.2 2 0 0 2 2 2 0 NinF protein Phosphodiest PF01663.22 OIR58300.1 - 4.6e-12 46.2 0.1 6.6e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase HEPN_SAV_6107 PF18726.1 OIR58300.1 - 0.0087 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 SAV_6107-like HEPN tRNA-synt_2d PF01409.20 OIR58301.1 - 2.4e-83 279.4 0.1 4.1e-83 278.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OIR58301.1 - 2.6e-11 43.7 0.4 6.9e-11 42.3 0.4 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 OIR58301.1 - 9e-08 31.8 0.0 1.4e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OIR58301.1 - 0.0012 18.0 0.1 0.0039 16.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OIR58301.1 - 0.02 14.9 0.1 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) N6_N4_Mtase PF01555.18 OIR58302.1 - 0.0046 16.7 0.4 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 DNA methylase Apolipoprotein PF01442.18 OIR58303.1 - 0.0065 16.4 30.0 0.014 15.3 20.0 2.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 OIR58303.1 - 0.029 14.9 10.0 0.029 14.9 10.0 5.1 1 1 3 4 4 4 0 YtxH-like protein HisKA_3 PF07730.13 OIR58303.1 - 0.52 10.9 10.6 38 4.9 2.6 4.7 1 1 3 4 4 4 0 Histidine kinase Chlorosome_CsmC PF11098.8 OIR58303.1 - 1.6 8.7 6.4 4 7.4 1.7 2.5 1 1 1 2 2 2 0 Chlorosome envelope protein C DUF883 PF05957.13 OIR58303.1 - 3 8.5 36.9 0.3 11.7 6.1 4.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) COMP PF11598.8 OIR58303.1 - 6.4 7.3 10.8 41 4.7 0.1 4.7 3 1 0 4 4 4 0 Cartilage oligomeric matrix protein Hus1 PF04005.12 OIR58304.1 - 0.00011 21.4 0.2 0.0093 15.1 0.2 2.2 2 0 0 2 2 2 2 Hus1-like protein UQ_con PF00179.26 OIR58305.1 - 1.8e-27 95.7 0.1 2.1e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OIR58305.1 - 0.017 15.0 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 OIR58305.1 - 0.033 13.9 0.1 0.042 13.6 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RFC1 PF08519.12 OIR58306.1 - 2e-21 76.8 0.1 3.7e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OIR58306.1 - 1.1e-12 48.2 0.2 7e-12 45.6 0.2 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OIR58306.1 - 3e-11 43.9 0.0 6.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OIR58306.1 - 2.6e-07 30.8 0.1 5.5e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 OIR58306.1 - 6e-06 26.2 0.8 2.7e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OIR58306.1 - 0.00024 21.5 0.0 0.00081 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OIR58306.1 - 0.00066 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 OIR58306.1 - 0.0026 17.1 0.1 0.0068 15.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin BRCT_2 PF16589.5 OIR58306.1 - 0.0069 16.8 0.5 0.022 15.1 0.1 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain AAA_14 PF13173.6 OIR58306.1 - 0.023 14.7 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OIR58306.1 - 0.038 14.3 0.0 0.85 9.9 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 OIR58306.1 - 0.049 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OIR58306.1 - 0.097 13.1 0.9 0.56 10.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OIR58306.1 - 0.11 12.4 0.2 0.47 10.4 0.1 2.0 1 1 0 2 2 2 0 NTPase PTCB-BRCT PF12738.7 OIR58306.1 - 0.12 12.4 0.1 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 twin BRCT domain tRNA-synt_1c PF00749.21 OIR58307.1 - 7.7e-99 330.5 0.0 1e-98 330.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OIR58307.1 - 4e-30 105.0 0.0 6.2e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 OIR58307.1 - 0.096 12.0 0.1 0.41 9.9 0.1 1.8 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Hyd_WA PF06462.12 OIR58307.1 - 0.13 12.3 0.0 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Propeller WD40 PF00400.32 OIR58308.1 - 2.9e-14 53.2 5.2 2.5e-05 25.0 0.2 4.9 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58308.1 - 2e-07 31.2 2.1 0.048 14.0 0.3 4.9 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OIR58308.1 - 4.7e-05 23.4 1.7 0.0089 15.9 0.4 3.0 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.6 OIR58308.1 - 0.036 13.3 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 zf-RING_2 PF13639.6 OIR58309.1 - 1.2e-14 54.4 9.0 1.5e-14 54.1 9.0 1.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OIR58309.1 - 3.9e-10 39.9 9.6 9.1e-10 38.7 9.6 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OIR58309.1 - 9.8e-10 38.1 8.5 1.3e-09 37.7 8.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR58309.1 - 1.4e-09 37.7 9.1 1.9e-09 37.2 9.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR58309.1 - 3.8e-09 36.4 7.7 5e-09 36.0 7.7 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OIR58309.1 - 4.5e-09 35.9 5.3 8e-09 35.1 5.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 OIR58309.1 - 1.3e-07 31.3 6.2 1.8e-07 30.9 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OIR58309.1 - 3.5e-07 30.1 5.7 5.7e-07 29.5 5.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 OIR58309.1 - 4.5e-05 23.0 6.7 8e-05 22.2 6.7 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OIR58309.1 - 0.00013 22.1 7.2 0.00035 20.7 7.2 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 OIR58309.1 - 0.00016 21.7 4.7 0.00047 20.1 4.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OIR58309.1 - 0.0023 17.8 7.3 0.0042 16.9 6.8 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 OIR58309.1 - 0.0036 17.4 5.6 0.0084 16.2 5.6 1.6 1 1 0 1 1 1 1 RING-variant domain PHD PF00628.29 OIR58309.1 - 0.0058 16.5 6.0 0.0088 15.9 6.0 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 OIR58309.1 - 0.0067 16.3 6.3 0.022 14.7 1.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 OIR58309.1 - 0.055 13.3 5.5 0.17 11.7 5.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 OIR58309.1 - 0.075 13.1 8.5 0.2 11.7 8.5 1.8 1 1 0 1 1 1 0 Zinc-finger zf-RVT PF13966.6 OIR58309.1 - 0.093 13.5 1.1 0.093 13.5 1.1 2.0 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase zf-Nse PF11789.8 OIR58309.1 - 0.13 12.1 5.2 0.19 11.6 5.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zf_RING PF16744.5 OIR58309.1 - 0.14 12.3 6.6 0.086 13.0 4.6 1.6 1 1 1 2 2 2 0 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 OIR58309.1 - 0.33 11.1 5.2 0.85 9.8 5.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 OIR58309.1 - 0.6 10.5 9.1 0.14 12.5 3.9 2.0 2 0 0 2 2 2 0 RING-like domain WD40 PF00400.32 OIR58310.1 - 2e-10 41.1 3.6 1.5e-07 31.9 0.1 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58310.1 - 9e-06 25.9 0.1 0.063 13.6 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OIR58310.1 - 0.0011 18.9 0.0 0.18 11.6 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1878 PF08963.10 OIR58311.1 - 0.011 16.3 0.8 1.3 9.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) APC1_C PF18122.1 OIR58311.1 - 0.019 14.9 0.4 9.8 6.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Cnd1 PF12717.7 OIR58311.1 - 0.088 12.8 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OIR58311.1 - 0.1 13.1 1.3 20 5.8 0.3 3.3 2 0 0 2 2 2 0 HEAT-like repeat CAF1A PF12253.8 OIR58312.1 - 6.1e-17 61.6 3.7 6.1e-17 61.6 3.7 2.6 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Pkinase PF00069.25 OIR58313.1 - 2.7e-66 223.6 0.0 3.1e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58313.1 - 4.4e-26 91.7 0.0 5.6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR58313.1 - 0.00081 18.8 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OIR58313.1 - 0.0038 17.2 0.5 0.0066 16.4 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF4904 PF16247.5 OIR58313.1 - 0.2 11.5 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) Helicase_C_2 PF13307.6 OIR58314.1 - 3.7e-47 160.7 0.0 1.4e-46 158.8 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OIR58314.1 - 2.6e-43 147.7 2.7 5.1e-43 146.7 2.7 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OIR58314.1 - 3.4e-06 27.2 0.8 0.00014 21.9 0.8 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OIR58314.1 - 0.00084 19.1 0.3 0.1 12.3 0.0 2.8 2 1 0 3 3 3 1 DEAD/DEAH box helicase HBB PF06777.11 OIR58314.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Helical and beta-bridge domain FleQ PF06490.11 OIR58314.1 - 0.072 13.5 0.1 0.24 11.8 0.1 1.9 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Occludin_ELL PF07303.13 OIR58314.1 - 0.079 13.7 1.0 0.35 11.6 0.5 2.3 2 0 0 2 2 2 0 Occludin homology domain MT-A70 PF05063.14 OIR58315.1 - 9.7e-13 48.4 0.1 1.4e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Ribosomal_L6e PF01159.19 OIR58315.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L6e SHNi-TPR PF10516.9 OIR58316.1 - 5.9e-13 48.0 0.5 5.9e-13 48.0 0.5 1.8 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 OIR58316.1 - 3.7e-08 33.5 3.5 9.7e-08 32.2 0.1 2.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OIR58316.1 - 1.8e-05 24.5 4.6 0.3 11.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OIR58316.1 - 0.00084 19.1 0.1 0.016 15.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OIR58316.1 - 0.0079 16.3 0.0 0.07 13.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF359 PF04019.12 OIR58316.1 - 0.015 14.9 0.1 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF359) SRX PF09201.10 OIR58316.1 - 0.13 12.1 0.6 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit TPR_6 PF13174.6 OIR58316.1 - 0.16 12.7 0.6 3 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OIR58316.1 - 0.47 10.4 0.1 0.47 10.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SICA_alpha PF12887.7 OIR58316.1 - 3.9 7.3 6.5 7.5 6.4 0.3 2.5 3 0 0 3 3 3 0 SICA extracellular alpha domain NIF3 PF01784.18 OIR58317.1 - 2.4e-61 207.5 0.0 2.8e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF99 PF01949.16 OIR58317.1 - 0.04 13.3 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 PseudoU_synth_1 PF01416.20 OIR58318.1 - 7.9e-27 93.9 0.0 4.4e-25 88.2 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase Neurensin PF14927.6 OIR58319.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Neurensin TFIID-18kDa PF02269.16 OIR58320.1 - 5.1e-09 36.0 0.6 1.6e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 OIR58320.1 - 0.0013 19.2 0.0 0.0026 18.2 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 OIR58320.1 - 0.098 12.7 0.1 3.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L4 PF00573.22 OIR58321.1 - 2.2e-36 125.4 0.1 3.2e-36 124.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OIR58321.1 - 8.7e-11 41.7 0.1 1.9e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Snf7 PF03357.21 OIR58322.1 - 0.0014 18.2 22.4 0.0018 17.9 22.4 1.1 1 0 0 1 1 1 1 Snf7 DUF3349 PF11829.8 OIR58322.1 - 0.0042 17.8 0.8 0.0042 17.8 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3349) HSCB_C PF07743.13 OIR58322.1 - 0.012 16.1 14.7 0.14 12.6 2.2 3.8 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Spidroin_N PF16763.5 OIR58322.1 - 0.012 15.6 3.6 0.024 14.6 3.6 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term DUF3662 PF12401.8 OIR58322.1 - 0.014 15.7 1.0 0.19 12.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) Endonuc-BglII PF09195.11 OIR58322.1 - 0.63 9.8 6.4 1.3 8.9 1.0 2.1 1 1 1 2 2 2 0 Restriction endonuclease BglII CbiG_C PF01890.16 OIR58322.1 - 0.65 10.6 6.0 1.8 9.2 1.4 2.4 2 1 0 2 2 2 0 Cobalamin synthesis G C-terminus DltD PF04914.12 OIR58322.1 - 1.3 8.3 8.0 0.45 9.8 1.1 2.1 1 1 1 2 2 2 0 DltD protein DUF2344 PF10105.9 OIR58322.1 - 1.5 8.7 10.8 9.6 6.0 10.8 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Histone_HNS PF00816.21 OIR58322.1 - 3 8.7 13.1 6.1 7.7 2.8 2.3 2 0 0 2 2 2 0 H-NS histone family Arc_PepC_II PF06847.11 OIR58322.1 - 5.5 7.6 5.4 1.4 9.5 0.8 2.4 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II SMC_Nse1 PF07574.13 OIR58323.1 - 1.8e-08 34.5 0.0 1.5e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 OIR58323.1 - 0.6 10.5 11.6 1.4 9.3 11.6 1.7 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 OIR58323.1 - 1.4 8.8 9.5 3.4 7.6 9.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ric8 PF10165.9 OIR58324.1 - 8.9e-20 71.2 0.8 2e-19 70.0 0.7 1.5 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DNA_primase_lrg PF04104.14 OIR58325.1 - 4e-57 193.6 0.0 5e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Memo PF01875.17 OIR58326.1 - 1.9e-33 115.8 0.0 2.3e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Rhabdo_ncap PF00945.18 OIR58327.1 - 0.027 13.4 2.5 0.046 12.6 2.5 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Paramyxo_ncap PF00973.19 OIR58327.1 - 0.58 9.0 4.9 0.78 8.6 4.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Rad21_Rec8_N PF04825.13 OIR58328.1 - 1.5e-23 83.0 0.0 2.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Protoglobin PF11563.8 OIR58329.1 - 0.033 14.1 0.1 9.4 6.1 0.0 2.8 2 1 1 3 3 3 0 Protoglobin PIEZO PF15917.5 OIR58330.1 - 0.3 10.5 10.2 0.65 9.4 10.2 1.6 1 0 0 1 1 1 0 Piezo V_ATPase_I PF01496.19 OIR58330.1 - 0.67 7.8 18.5 0.23 9.3 14.6 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 OIR58330.1 - 2.3 7.7 8.5 4 6.9 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit eRF1_1 PF03463.15 OIR58333.1 - 3.4e-30 104.7 0.9 7.8e-30 103.5 0.9 1.6 1 0 0 1 1 1 1 eRF1 domain 1 AAA PF00004.29 OIR58334.1 - 3e-44 150.6 0.1 1e-43 149.0 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR58334.1 - 1.4e-11 44.0 0.0 2.8e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OIR58334.1 - 1.4e-09 38.3 0.0 5e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OIR58334.1 - 7.2e-08 33.0 0.1 0.00014 22.3 0.1 2.4 1 1 1 2 2 2 2 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 OIR58334.1 - 2e-07 30.8 0.8 4.2e-07 29.8 0.8 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OIR58334.1 - 3.5e-07 30.3 0.1 3.4e-06 27.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OIR58334.1 - 4.2e-07 29.8 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OIR58334.1 - 7.7e-05 23.3 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OIR58334.1 - 9.8e-05 22.6 0.3 0.011 16.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 OIR58334.1 - 0.00053 19.3 0.0 0.00093 18.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 OIR58334.1 - 0.00066 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 OIR58334.1 - 0.0018 18.2 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OIR58334.1 - 0.0024 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 OIR58334.1 - 0.0031 17.5 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OIR58334.1 - 0.0032 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 OIR58334.1 - 0.0032 16.9 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OIR58334.1 - 0.0037 17.6 0.0 0.017 15.5 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 OIR58334.1 - 0.0041 17.3 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OIR58334.1 - 0.005 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 OIR58334.1 - 0.0074 16.0 0.1 2.3 7.9 0.0 2.8 2 1 1 3 3 3 1 Thymidylate kinase NACHT PF05729.12 OIR58334.1 - 0.011 15.7 0.0 0.082 12.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 OIR58334.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 OIR58334.1 - 0.013 15.2 0.4 0.053 13.2 0.0 2.2 3 1 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OIR58334.1 - 0.015 15.0 0.0 0.062 13.0 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 OIR58334.1 - 0.022 14.7 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 OIR58334.1 - 0.028 13.8 0.3 0.28 10.5 0.0 2.4 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 OIR58334.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 OIR58334.1 - 0.059 13.8 0.1 1.4 9.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OIR58334.1 - 0.079 12.7 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OIR58334.1 - 0.11 12.0 1.6 0.29 10.7 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 OIR58334.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OIR58334.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain SH3_15 PF18346.1 OIR58334.1 - 0.17 12.2 0.5 0.43 10.9 0.5 1.7 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain AAA_21 PF13304.6 OIR58334.1 - 0.18 11.6 0.0 5.5 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Sas10_Utp3 PF04000.15 OIR58335.1 - 1.4e-10 41.6 1.2 3.4e-10 40.4 0.5 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Sas10 PF09368.10 OIR58335.1 - 0.0024 18.3 7.6 0.0024 18.3 7.6 3.2 4 0 0 4 4 4 2 Sas10 C-terminal domain Suf PF05843.14 OIR58336.1 - 1.1e-06 28.8 0.2 2.8e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OIR58336.1 - 0.0012 19.5 0.3 0.64 11.0 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 OIR58337.1 - 2.7e-21 75.5 7.7 6.4e-05 23.5 0.6 6.8 6 0 0 6 6 6 5 Sel1 repeat TPR_2 PF07719.17 OIR58337.1 - 0.15 12.3 3.0 7.1 7.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR58337.1 - 0.86 9.9 4.3 1.6 9.0 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RNB PF00773.19 OIR58338.1 - 2.2e-98 329.6 0.0 3.4e-98 329.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 OIR58338.1 - 8.7e-18 64.1 0.0 2.5e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 OIR58338.1 - 1.2e-09 38.5 0.1 8.4e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 PIN domain Rrp44_S1 PF17215.3 OIR58338.1 - 7.3e-08 32.3 0.8 4.7e-07 29.7 0.8 2.3 1 1 0 1 1 1 1 S1 domain CSD2 PF17876.1 OIR58338.1 - 9.7e-07 28.9 0.0 0.00016 21.8 0.0 2.8 2 1 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 OIR58338.1 - 0.0027 17.3 0.0 0.0097 15.6 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease B OB domain TcfC PF16967.5 OIR58338.1 - 0.08 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 E-set like domain TSP9 PF11493.8 OIR58339.1 - 0.099 13.3 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 CBFD_NFYB_HMF PF00808.23 OIR58340.1 - 1.8e-23 82.6 0.1 2.3e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OIR58340.1 - 3.2e-05 24.3 0.1 4.1e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 OIR58340.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 OIR58340.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-X PF09415.10 OIR58340.1 - 0.12 12.7 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X ELYS PF13934.6 OIR58341.1 - 0.058 13.4 0.0 0.5 10.3 0.0 2.1 1 1 0 1 1 1 0 Nuclear pore complex assembly Asp PF00026.23 OIR58342.1 - 5e-45 154.3 0.0 5.7e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OIR58342.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Hist_deacetyl PF00850.19 OIR58343.1 - 2.3e-81 273.7 0.0 3e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain STAG PF08514.11 OIR58344.1 - 1.7e-13 50.5 0.6 5.9e-13 48.7 0.6 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 OIR58344.1 - 0.022 15.0 0.2 16 6.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Cnd1 PF12717.7 OIR58344.1 - 0.06 13.4 0.0 11 6.0 0.0 3.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TRP_2 PF08344.11 OIR58344.1 - 0.092 13.0 0.1 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Transient receptor ion channel II G-gamma PF00631.22 OIR58345.1 - 1.7e-08 34.3 0.1 1.8e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 GGL domain Ran_BP1 PF00638.18 OIR58346.1 - 1.1e-16 61.2 0.1 9e-16 58.2 0.1 2.1 1 1 0 1 1 1 1 RanBP1 domain AnfO_nitrog PF09582.10 OIR58346.1 - 0.0084 15.5 0.2 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Iron only nitrogenase protein AnfO (AnfO_nitrog) RNA_pol_Rpb8 PF03870.15 OIR58347.1 - 2.8e-35 121.5 0.2 3.3e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OIR58347.1 - 1.5e-06 28.3 1.5 3.6e-05 23.8 1.5 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G Ish1 PF10281.9 OIR58348.1 - 0.11 12.8 0.1 7.8 6.9 0.1 2.5 2 1 1 3 3 3 0 Putative stress-responsive nuclear envelope protein NopRA1 PF16201.5 OIR58349.1 - 1.5e-19 70.4 0.5 2.7e-19 69.6 0.5 1.4 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 TBPIP PF07106.13 OIR58349.1 - 0.038 13.9 0.6 0.47 10.4 0.0 2.8 3 0 0 3 3 3 0 TBPIP/Hop2 winged helix domain SANTA PF09133.10 OIR58350.1 - 2.3e-14 53.6 0.3 6.7e-14 52.1 0.3 1.7 1 1 0 1 1 1 1 SANTA (SANT Associated) Rol_Rep_N PF18106.1 OIR58351.1 - 0.043 14.1 0.1 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain SAPS PF04499.15 OIR58351.1 - 0.84 8.4 5.1 16 4.1 4.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 OIR58351.1 - 6.4 6.0 21.3 11 5.2 21.3 1.3 1 0 0 1 1 1 0 BUD22 Thymidylat_synt PF00303.19 OIR58353.1 - 2.5e-102 341.6 0.0 2.8e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Mit_KHE1 PF10173.9 OIR58353.1 - 0.048 13.7 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Plus-3 PF03126.18 OIR58354.1 - 1.8e-16 60.6 0.2 5.7e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain DUF3499 PF12005.8 OIR58354.1 - 0.38 11.4 4.7 3.7 8.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) MscS_TM PF12794.7 OIR58354.1 - 7.7 5.3 5.7 15 4.3 5.7 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 His_Phos_2 PF00328.22 OIR58355.1 - 8.8e-17 61.5 0.0 4.5e-13 49.3 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) DUF4710 PF15828.5 OIR58355.1 - 0.026 14.6 1.9 0.14 12.3 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) SHMT PF00464.19 OIR58356.1 - 2.2e-157 523.8 0.1 2.6e-157 523.5 0.1 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OIR58356.1 - 0.00016 21.0 0.0 0.00075 18.9 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Phage_capsid PF05065.13 OIR58356.1 - 0.015 14.6 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 0 Phage capsid family Chs7 PF12271.8 OIR58357.1 - 2.4e-57 194.5 26.8 2.9e-57 194.3 26.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ssl1 PF04056.14 OIR58359.1 - 4.4e-11 43.0 0.0 4.8e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like TssR PF17643.1 OIR58359.1 - 0.015 13.3 0.0 0.022 12.7 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR VWA_3 PF13768.6 OIR58359.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain ABC_tran PF00005.27 OIR58360.1 - 4e-27 95.4 0.0 2.3e-26 92.9 0.0 2.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 OIR58360.1 - 3.4e-06 26.7 0.5 0.014 14.8 0.0 2.8 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OIR58360.1 - 4.6e-05 23.4 0.2 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_membrane PF00664.23 OIR58360.1 - 0.00048 19.9 10.9 0.0011 18.7 10.7 1.6 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_23 PF13476.6 OIR58360.1 - 0.0012 19.4 4.6 0.0036 17.8 0.5 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OIR58360.1 - 0.0017 18.6 0.1 0.061 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OIR58360.1 - 0.0046 16.7 1.1 1.5 8.6 0.2 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 OIR58360.1 - 0.025 14.9 0.2 0.067 13.6 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OIR58360.1 - 0.04 14.3 0.3 2.7 8.4 0.1 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OIR58360.1 - 0.049 13.4 0.3 0.23 11.2 0.0 2.3 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 OIR58360.1 - 0.063 13.0 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OIR58360.1 - 0.072 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OIR58360.1 - 0.081 13.1 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OIR58360.1 - 0.2 11.9 1.4 0.66 10.2 0.4 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Ninjurin PF04923.12 OIR58360.1 - 7.1 6.6 9.3 2.6 8.0 2.4 3.6 3 1 1 4 4 4 0 Ninjurin RhoGEF PF00621.20 OIR58362.1 - 9.7e-33 113.9 3.3 1.3e-32 113.5 3.3 1.2 1 0 0 1 1 1 1 RhoGEF domain C2 PF00168.30 OIR58362.1 - 6.2e-08 32.9 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Spc7 PF08317.11 OIR58362.1 - 0.19 10.6 1.8 0.16 10.8 0.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein BIR PF00653.21 OIR58364.1 - 1.7e-38 131.1 6.0 2.5e-19 69.7 1.5 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 OIR58364.1 - 0.002 18.2 0.1 0.22 11.6 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.15 OIR58364.1 - 0.0091 16.0 1.4 0.27 11.3 0.3 2.6 2 0 0 2 2 2 1 BED zinc finger zf-ribbon_3 PF13248.6 OIR58364.1 - 0.97 8.9 7.1 2.7 7.5 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain TMEM100 PF16311.5 OIR58365.1 - 0.094 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Dynein_light PF01221.18 OIR58366.1 - 9.2e-16 57.9 0.1 1.1e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 CdiI_2 PF18593.1 OIR58366.1 - 0.085 13.5 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 CdiI immunity protein COG5 PF10392.9 OIR58367.1 - 0.065 13.4 1.8 0.13 12.4 0.5 2.0 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Helicase_C_2 PF13307.6 OIR58369.1 - 6.9e-49 166.3 0.0 3e-48 164.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 OIR58369.1 - 2.7e-40 137.8 0.0 6.5e-40 136.6 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 OIR58369.1 - 1.5e-05 25.1 0.1 0.00016 21.7 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OIR58369.1 - 0.00027 20.7 0.0 0.056 13.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 OIR58369.1 - 0.01 15.3 0.1 0.35 10.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 OIR58369.1 - 0.031 14.5 0.0 7.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_pol_L_2 PF13656.6 OIR58370.1 - 1.3e-18 66.5 0.0 2.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OIR58370.1 - 6.4e-06 25.5 0.0 2.2e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Myb_DNA-binding PF00249.31 OIR58371.1 - 2.5e-12 46.8 2.1 2.6e-06 27.5 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR58371.1 - 3.1e-10 40.2 0.8 0.0009 19.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 OIR58371.1 - 3.5e-05 23.8 0.5 0.014 15.4 0.1 2.5 1 1 1 2 2 2 2 SLIDE MCRS_N PF13325.6 OIR58371.1 - 0.00042 20.4 0.2 0.0011 19.0 0.1 1.8 1 1 1 2 2 2 1 N-terminal region of micro-spherule protein MC1 PF05854.11 OIR58371.1 - 0.011 16.0 0.6 0.05 13.9 0.0 2.1 2 0 0 2 2 2 0 Non-histone chromosomal protein MC1 RPAP3_C PF13877.6 OIR58371.1 - 0.02 15.4 0.4 0.084 13.4 0.0 2.1 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 Glyco_hydro_130 PF04041.13 OIR58372.1 - 0.14 11.1 0.0 1.3 7.8 0.0 1.9 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase BIR PF00653.21 OIR58372.1 - 2.1 9.0 10.5 1.5 9.6 5.3 2.8 1 1 2 3 3 3 0 Inhibitor of Apoptosis domain tRNA-synt_1e PF01406.19 OIR58373.1 - 2.7e-102 342.2 0.1 3.5e-102 341.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OIR58373.1 - 8.1e-09 34.7 0.4 2.7e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OIR58373.1 - 4.2e-06 25.3 0.0 3.9e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 OIR58373.1 - 0.002 17.1 0.5 1.2 8.0 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (K) Tfb4 PF03850.14 OIR58376.1 - 4.3e-08 33.0 1.2 7.8e-08 32.1 1.1 1.5 1 1 0 1 1 1 1 Transcription factor Tfb4 Polysacc_deac_1 PF01522.21 OIR58377.1 - 2.3e-13 50.1 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase APOBEC1 PF18769.1 OIR58377.1 - 0.063 13.5 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 APOBEC1 ADIP PF11559.8 OIR58378.1 - 1.2e-11 45.0 16.6 1.2e-11 45.0 16.6 3.2 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding RAB3GAP2_N PF14655.6 OIR58378.1 - 0.0037 16.6 0.4 0.0066 15.8 0.4 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Leu_zip PF15294.6 OIR58378.1 - 0.0041 16.7 14.9 0.0041 16.7 14.9 2.9 1 1 2 3 3 3 1 Leucine zipper T2SS_PulS_OutS PF09691.10 OIR58378.1 - 0.34 11.1 3.9 4.1 7.6 0.0 3.2 3 1 1 4 4 4 0 Type II secretion system pilotin lipoprotein (PulS_OutS) WXG100 PF06013.12 OIR58378.1 - 1.1 9.6 6.0 9.7 6.5 0.2 3.7 3 2 0 3 3 3 0 Proteins of 100 residues with WXG Suf PF05843.14 OIR58378.1 - 1.4 8.8 13.5 0.048 13.6 2.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Fzo_mitofusin PF04799.13 OIR58378.1 - 2.1 7.9 12.8 3.3 7.3 3.1 2.8 2 1 0 2 2 2 0 fzo-like conserved region Exonuc_VII_L PF02601.15 OIR58378.1 - 8.1 5.9 23.3 1.9 8.0 7.9 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Synaptobrevin PF00957.21 OIR58379.1 - 5.1e-19 67.8 0.1 6.6e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 OIR58379.1 - 0.013 15.6 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter EF-1_beta_acid PF10587.9 OIR58379.1 - 2.5 8.6 9.1 11 6.6 3.6 3.2 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Symplekin_C PF12295.8 OIR58381.1 - 3.5e-12 46.8 1.7 5.2e-10 39.7 0.0 2.9 2 1 0 2 2 2 2 Symplekin tight junction protein C terminal HEAT_2 PF13646.6 OIR58381.1 - 0.013 15.9 4.2 0.53 10.7 0.5 4.0 4 1 1 5 5 5 0 HEAT repeats CRR7 PF12095.8 OIR58381.1 - 0.079 13.4 0.2 0.55 10.7 0.1 2.5 1 1 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 HSP70 PF00012.20 OIR58382.1 - 9.9e-252 836.4 6.5 1.1e-251 836.2 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OIR58382.1 - 3.4e-13 49.1 0.1 4.4e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein SYF2 PF08231.12 OIR58382.1 - 0.0087 16.5 0.4 0.025 15.0 0.4 1.7 1 0 0 1 1 1 1 SYF2 splicing factor Hydantoinase_A PF01968.18 OIR58382.1 - 0.07 12.4 0.0 0.16 11.2 0.0 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase ATP-cone PF03477.16 OIR58382.1 - 0.099 13.2 0.9 0.45 11.1 0.2 2.5 2 0 0 2 2 2 0 ATP cone domain Zw10 PF06248.13 OIR58382.1 - 0.81 8.2 3.7 1.2 7.6 3.7 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Atg14 PF10186.9 OIR58382.1 - 4.6 6.2 6.0 9.1 5.3 6.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4231 PF14015.6 OIR58383.1 - 0.23 12.0 1.3 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Pkinase PF00069.25 OIR58384.1 - 1.1e-62 211.9 0.0 1.5e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58384.1 - 8.1e-34 117.1 0.0 1.5e-33 116.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR58384.1 - 7.8e-08 32.0 0.1 7.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OIR58384.1 - 7.8e-05 21.8 0.1 0.00011 21.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OIR58384.1 - 0.00058 18.8 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OIR58384.1 - 0.0022 18.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR58384.1 - 0.0076 15.6 0.0 0.026 13.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OIR58384.1 - 0.023 14.3 0.2 6.7 6.3 0.2 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1999 PF09390.10 OIR58384.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) UFD1 PF03152.14 OIR58385.1 - 8e-52 175.2 0.0 9.9e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-C2H2_4 PF13894.6 OIR58386.1 - 0.00046 20.8 3.2 0.0021 18.7 3.2 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger SCAN PF02023.17 OIR58386.1 - 0.018 14.8 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 SCAN domain FOXP-CC PF16159.5 OIR58386.1 - 0.028 15.0 1.3 0.082 13.5 1.3 1.7 1 0 0 1 1 1 0 FOXP coiled-coil domain DinI PF06183.13 OIR58386.1 - 0.084 13.2 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 DinI-like family zf-BED PF02892.15 OIR58386.1 - 0.085 12.9 4.9 0.21 11.7 4.9 1.7 1 0 0 1 1 1 0 BED zinc finger F_actin_cap_B PF01115.17 OIR58388.1 - 6.8e-24 84.8 4.4 4.4e-16 59.2 3.1 3.0 2 1 0 2 2 2 2 F-actin capping protein, beta subunit DeoRC PF00455.22 OIR58388.1 - 0.028 14.3 0.0 0.14 12.1 0.2 2.0 2 1 0 2 2 2 0 DeoR C terminal sensor domain Proteasome PF00227.26 OIR58389.1 - 1.1e-45 155.4 0.2 1.3e-45 155.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Citrate_synt PF00285.21 OIR58390.1 - 6e-80 269.0 0.0 7.1e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain RRM_1 PF00076.22 OIR58391.1 - 3.5e-20 71.6 0.0 4.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OIR58391.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CIAPIN1 PF05093.13 OIR58392.1 - 4.7e-16 59.1 13.9 2.1e-14 53.8 13.9 2.2 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HECT PF00632.25 OIR58393.1 - 3.4e-70 237.0 0.0 4.7e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OIR58393.1 - 1.6e-17 63.3 4.3 2e-09 37.4 1.1 2.8 3 0 0 3 3 3 2 WW domain C2 PF00168.30 OIR58393.1 - 9.5e-13 48.3 0.0 2.4e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain YacG PF03884.14 OIR58395.1 - 0.007 16.1 0.0 11 5.8 0.0 4.3 5 0 0 5 5 5 1 DNA gyrase inhibitor YacG DUF1487 PF07368.11 OIR58395.1 - 0.067 12.6 0.0 4 6.8 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1487) zf-RING_5 PF14634.6 OIR58396.1 - 1.5e-05 24.9 6.1 3.1e-05 23.8 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OIR58396.1 - 0.0036 17.3 2.0 0.012 15.6 2.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger DUF4795 PF16043.5 OIR58396.1 - 0.0044 16.6 0.0 0.0063 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) zf-CRD PF17979.1 OIR58396.1 - 0.08 13.0 5.3 0.028 14.5 1.9 1.8 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions zf-C3HC4 PF00097.25 OIR58396.1 - 0.1 12.5 5.3 0.23 11.4 5.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR58396.1 - 0.12 12.8 5.0 0.51 10.7 5.0 2.1 1 1 0 1 1 1 0 Ring finger domain WHEP-TRS PF00458.20 OIR58396.1 - 0.84 9.8 4.2 1.6 9.0 4.2 1.4 1 0 0 1 1 1 0 WHEP-TRS domain Prok-RING_4 PF14447.6 OIR58396.1 - 8.2 6.4 11.2 3.4 7.6 7.0 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Sec7_N PF12783.7 OIR58397.1 - 0.00036 20.5 5.4 0.00036 20.5 5.4 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal 4HB PF17947.1 OIR58397.1 - 0.039 14.0 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Four helical bundle domain Myb_DNA-bind_5 PF13873.6 OIR58397.1 - 0.066 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MyTH4 PF00784.17 OIR58397.1 - 0.3 11.6 1.4 2 9.0 0.1 3.0 3 0 0 3 3 3 0 MyTH4 domain HSP90 PF00183.18 OIR58398.1 - 1.3e-146 489.5 5.2 1.3e-146 489.5 5.2 2.2 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.6 OIR58398.1 - 1.5e-09 37.8 1.5 4.4e-09 36.3 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OIR58398.1 - 2.4e-06 28.0 0.1 9.2e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IF4E PF01652.18 OIR58399.1 - 1.5e-38 132.1 0.0 1.7e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NusG_II PF07009.11 OIR58400.1 - 0.0077 16.4 0.8 1.7 8.9 0.1 4.3 5 1 0 5 5 5 1 NusG domain II ORF_12_N PF18042.1 OIR58400.1 - 0.1 13.0 2.9 7.8 7.0 0.0 4.4 5 0 0 5 5 5 0 ORF 12 gene product N-terminal GPI-anchored PF10342.9 OIR58400.1 - 0.14 12.9 3.9 1.7 9.5 0.0 4.3 5 0 0 5 5 5 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cupredoxin_1 PF13473.6 OIR58400.1 - 0.47 10.6 5.3 0.63 10.2 0.0 3.8 6 0 0 6 6 6 0 Cupredoxin-like domain zf-C3HC4_3 PF13920.6 OIR58404.1 - 0.039 13.8 5.5 0.077 12.9 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OIR58404.1 - 0.27 11.6 8.4 0.68 10.3 8.4 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OIR58404.1 - 1.3 8.9 6.4 3.7 7.5 6.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OIR58404.1 - 2.1 8.4 7.9 4.9 7.2 7.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-TFIIIC PF12660.7 OIR58406.1 - 0.016 15.2 0.0 0.09 12.7 0.0 2.3 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex Spiralin PF05215.13 OIR58406.1 - 0.03 13.7 0.1 0.91 8.8 0.1 3.2 3 1 1 4 4 4 0 Spiralin Cas_Cas4 PF01930.17 OIR58406.1 - 0.83 9.7 12.8 1.1 9.3 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function DUF83 DUF3253 PF11625.8 OIR58407.1 - 0.068 13.4 0.0 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) DUF1297 PF06973.12 OIR58408.1 - 0.046 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) Vps16_N PF04841.13 OIR58409.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region FadA PF09403.10 OIR58413.1 - 4.7 7.8 7.3 0.53 10.8 2.2 2.1 2 0 0 2 2 2 0 Adhesion protein FadA SfsA_N PF17746.1 OIR58414.1 - 0.11 12.7 0.1 2.9 8.1 0.0 2.6 2 1 0 2 2 2 0 SfsA N-terminal OB domain Ribosomal_S5 PF00333.20 OIR58415.1 - 2.3e-26 91.5 3.4 3.8e-26 90.8 3.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OIR58415.1 - 2.5e-23 81.3 0.0 5.4e-23 80.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain WD40 PF00400.32 OIR58417.1 - 1.5e-12 47.8 2.3 3.4e-07 30.9 0.1 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58417.1 - 2.3e-05 24.6 1.0 0.018 15.3 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OIR58417.1 - 0.0011 18.0 0.0 0.32 9.9 0.0 2.7 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA PF00004.29 OIR58418.1 - 1.6e-41 141.8 0.0 4.2e-41 140.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR58418.1 - 1.1e-08 34.8 0.1 2.1e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OIR58418.1 - 7.3e-07 29.1 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 OIR58418.1 - 1.6e-06 28.4 0.0 7.4e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OIR58418.1 - 2.7e-05 23.5 0.0 4.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OIR58418.1 - 7.8e-05 23.1 0.0 0.007 16.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 OIR58418.1 - 8.4e-05 21.9 0.4 0.34 10.0 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain AAA_22 PF13401.6 OIR58418.1 - 0.0001 22.6 0.1 0.017 15.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 OIR58418.1 - 0.00048 20.4 0.2 0.0027 18.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OIR58418.1 - 0.00052 20.0 0.3 0.0038 17.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OIR58418.1 - 0.001 19.6 0.2 0.0096 16.5 0.1 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OIR58418.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OIR58418.1 - 0.0022 18.3 0.0 0.0066 16.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 OIR58418.1 - 0.0031 17.5 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OIR58418.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 OIR58418.1 - 0.014 15.3 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OIR58418.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OIR58418.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 OIR58418.1 - 0.035 13.8 0.4 0.21 11.3 0.1 2.3 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 OIR58418.1 - 0.051 13.0 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OIR58418.1 - 0.066 13.1 0.2 0.58 10.1 0.1 2.5 2 1 1 3 3 3 0 NACHT domain AAA_25 PF13481.6 OIR58418.1 - 0.086 12.4 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OIR58418.1 - 0.094 12.1 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 OIR58418.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 OIR58418.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 OIR58418.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OIR58418.1 - 0.26 11.0 0.6 0.69 9.6 0.6 1.7 1 1 0 1 1 1 0 AAA domain RhoGEF PF00621.20 OIR58419.1 - 9.1e-28 97.7 0.0 1.9e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 OIR58419.1 - 2.5e-08 34.0 0.1 2.6e-07 30.8 0.1 2.5 2 1 0 2 2 2 1 CDC24 Calponin PH PF00169.29 OIR58419.1 - 0.014 15.9 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 PH domain PCRF PF03462.18 OIR58419.1 - 0.071 13.0 0.2 3.1 7.6 0.0 2.9 3 0 0 3 3 3 0 PCRF domain Bromodomain PF00439.25 OIR58419.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain FdhE PF04216.12 OIR58420.1 - 0.0028 17.6 3.6 0.0033 17.4 3.6 1.1 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation MEDS PF14417.6 OIR58420.1 - 0.015 15.1 3.0 0.017 14.9 1.0 1.8 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain GSCFA PF08885.11 OIR58420.1 - 0.046 13.4 0.7 0.062 12.9 0.7 1.2 1 0 0 1 1 1 0 GSCFA family DUF99 PF01949.16 OIR58420.1 - 0.049 13.0 1.8 0.076 12.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF1779 PF08680.10 OIR58420.1 - 0.094 12.9 2.1 0.13 12.4 2.1 1.2 1 0 0 1 1 1 0 TATA-box binding Cas_Csy4 PF09618.10 OIR58420.1 - 0.37 10.9 6.2 0.45 10.6 6.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Fez1 PF06818.15 OIR58420.1 - 0.47 10.9 15.6 0.64 10.4 15.6 1.3 1 1 0 1 1 1 0 Fez1 Atg14 PF10186.9 OIR58420.1 - 2.9 6.9 15.5 3.2 6.7 15.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5401 PF17380.2 OIR58420.1 - 3.5 5.6 15.9 4.5 5.2 15.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Exonuc_VII_L PF02601.15 OIR58420.1 - 6.9 6.1 10.1 7.8 6.0 10.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 OIR58420.1 - 7 5.8 8.1 8 5.6 8.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein ASF1_hist_chap PF04729.13 OIR58421.1 - 4.5e-46 156.6 0.1 5.3e-46 156.3 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Archease PF01951.16 OIR58422.1 - 9.2e-29 100.5 0.1 1e-28 100.3 0.1 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) Dynamin_M PF01031.20 OIR58423.1 - 4.5e-92 308.3 7.5 5.9e-92 307.9 0.0 2.9 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 OIR58423.1 - 4.2e-55 186.4 0.0 1e-54 185.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OIR58423.1 - 7.9e-28 96.5 5.8 7.9e-28 96.5 5.8 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OIR58423.1 - 6e-06 26.3 0.1 2.6e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OIR58423.1 - 0.046 13.9 0.2 0.74 10.0 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OIR58423.1 - 0.08 13.3 0.0 0.32 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain BAG PF02179.16 OIR58423.1 - 0.21 12.0 1.6 1.2 9.6 1.0 2.5 3 0 0 3 3 3 0 BAG domain AAA_15 PF13175.6 OIR58423.1 - 0.36 10.5 6.1 1.9 8.1 0.1 2.7 3 0 0 3 3 3 0 AAA ATPase domain THOC7 PF05615.13 OIR58423.1 - 3.2 8.1 6.1 2.3 8.5 1.9 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 ProRS-C_1 PF09180.11 OIR58424.1 - 3.5e-17 62.4 0.6 3.5e-17 62.4 0.6 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 OIR58424.1 - 7e-17 62.0 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OIR58424.1 - 4.5e-15 55.6 0.2 1.3e-14 54.1 0.2 1.8 1 0 0 1 1 1 1 Anticodon binding domain GPW_gp25 PF04965.14 OIR58424.1 - 0.051 13.3 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme Omega-toxin PF06357.11 OIR58424.1 - 0.083 12.7 0.8 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 Omega-atracotoxin CCDC-167 PF15188.6 OIR58424.1 - 0.79 10.1 4.4 1.3 9.4 0.3 2.7 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 PEP-utilisers_N PF05524.13 OIR58424.1 - 0.88 9.8 3.8 4.7 7.4 0.1 2.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal HA2 PF04408.23 OIR58425.1 - 5.5e-14 52.4 0.0 5.5e-14 52.4 0.0 3.5 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OIR58425.1 - 2.8e-13 50.2 0.1 2.8e-13 50.2 0.1 2.6 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OIR58425.1 - 1.9e-11 44.0 0.2 5.4e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OIR58425.1 - 7.7e-05 23.1 0.3 0.00027 21.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OIR58425.1 - 0.00088 19.3 0.5 0.00088 19.3 0.5 4.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OIR58425.1 - 0.0017 18.7 0.0 0.0067 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 OIR58425.1 - 0.0023 17.9 0.1 0.0055 16.7 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 OIR58425.1 - 0.012 15.4 0.1 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain OB_NTP_bind PF07717.16 OIR58425.1 - 0.051 13.9 0.0 0.4 11.1 0.0 2.5 2 0 0 2 2 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_25 PF13481.6 OIR58425.1 - 0.13 11.8 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rrp44_CSD1 PF17216.3 OIR58425.1 - 1.3 8.7 4.0 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 Rrp44-like cold shock domain Peptidase_S64 PF08192.11 OIR58425.1 - 1.8 6.9 15.5 2.9 6.3 15.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 RNase_P_Rpp14 PF01900.19 OIR58426.1 - 2.9e-14 53.2 0.0 3.4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family AAA PF00004.29 OIR58427.1 - 5.8e-16 59.1 0.0 1.5e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OIR58427.1 - 5.9e-16 58.7 0.0 1e-13 51.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 OIR58427.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OIR58427.1 - 6.2e-06 26.1 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OIR58427.1 - 8.6e-06 26.2 0.1 0.0015 19.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OIR58427.1 - 2.1e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 OIR58427.1 - 4.4e-05 23.5 0.0 0.00013 22.0 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 OIR58427.1 - 9.2e-05 22.7 0.2 0.022 15.0 0.2 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 OIR58427.1 - 0.00031 20.0 0.0 0.00049 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 OIR58427.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 OIR58427.1 - 0.0009 19.1 0.0 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OIR58427.1 - 0.0017 17.6 0.2 0.055 12.7 0.2 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OIR58427.1 - 0.0019 17.7 0.2 0.095 12.1 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 OIR58427.1 - 0.0024 17.6 0.0 0.0073 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OIR58427.1 - 0.0038 16.6 0.0 0.034 13.5 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rep_fac_C PF08542.11 OIR58427.1 - 0.0064 16.9 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain ResIII PF04851.15 OIR58427.1 - 0.007 16.4 0.0 0.036 14.1 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OIR58427.1 - 0.01 15.6 0.1 0.3 10.8 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_2 PF07724.14 OIR58427.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_assoc_2 PF16193.5 OIR58427.1 - 0.014 15.7 0.0 0.04 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain Viral_helicase1 PF01443.18 OIR58427.1 - 0.015 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 OIR58427.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GPAT_N PF14829.6 OIR58427.1 - 0.035 14.1 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ATPase_2 PF01637.18 OIR58427.1 - 0.036 14.0 0.0 0.075 12.9 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OIR58427.1 - 0.039 13.5 0.1 0.1 12.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OIR58427.1 - 0.041 14.4 0.0 0.059 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OIR58427.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 OIR58427.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.6 OIR58427.1 - 0.066 13.5 0.1 1.2 9.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 OIR58427.1 - 0.08 12.3 0.0 3.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein NB-ARC PF00931.22 OIR58427.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 OIR58427.1 - 0.11 12.2 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 OIR58427.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 OIR58427.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin DUF4470 PF14737.6 OIR58427.1 - 0.16 12.2 0.1 6.2 7.1 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4470) Mannosyl_trans PF05007.13 OIR58428.1 - 4.9e-46 157.7 19.1 4.3e-45 154.6 19.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 OIR58428.1 - 2.3e-09 37.3 10.7 2.3e-09 37.3 10.7 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 OIR58428.1 - 5.4e-05 22.4 12.7 7.6e-05 21.9 12.7 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2079 PF09852.9 OIR58428.1 - 0.00069 18.6 5.0 0.00069 18.6 5.0 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2079) PMT_2 PF13231.6 OIR58428.1 - 0.011 16.0 4.0 0.011 16.0 4.0 2.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Sugar_tr PF00083.24 OIR58429.1 - 4.6e-43 147.7 24.7 4.1e-23 81.9 6.6 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OIR58429.1 - 3.6e-19 68.9 20.8 3.6e-19 68.9 20.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2515 PF10720.9 OIR58429.1 - 0.51 9.5 3.4 0.81 8.8 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) Utp14 PF04615.13 OIR58430.1 - 1.8e-30 106.3 48.0 2.2e-19 69.5 15.0 2.2 1 1 1 2 2 2 2 Utp14 protein Suf PF05843.14 OIR58431.1 - 2.3e-08 34.4 0.0 3.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OIR58431.1 - 0.008 16.9 0.0 17 6.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat MFS_1_like PF12832.7 OIR58432.1 - 4.4e-24 85.1 19.6 6.7e-23 81.2 17.9 2.5 1 1 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 OIR58432.1 - 1.6e-05 24.1 7.1 1.6e-05 24.1 7.1 3.3 4 1 0 4 4 4 1 Nucleoside H+ symporter SNARE_assoc PF09335.11 OIR58432.1 - 0.00029 21.3 0.9 0.00029 21.3 0.9 3.4 3 1 0 3 3 3 1 SNARE associated Golgi protein TRAP_alpha PF03896.16 OIR58432.1 - 0.0033 16.7 0.4 0.0082 15.4 0.2 1.7 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Baculo_LEF-2 PF03041.14 OIR58432.1 - 0.34 10.5 1.8 0.49 10.0 0.1 2.2 3 0 0 3 3 3 0 lef-2 TRIQK PF15168.6 OIR58432.1 - 8.1 6.4 10.0 0.35 10.8 0.4 3.4 4 0 0 4 4 4 0 Triple QxxK/R motif-containing protein family HAGH_C PF16123.5 OIR58433.1 - 9.6e-16 58.1 0.1 1.4e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OIR58433.1 - 4.2e-07 30.2 4.5 1.7e-06 28.2 4.5 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OIR58433.1 - 0.0012 18.4 0.2 0.0024 17.4 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain O-FucT PF10250.9 OIR58434.1 - 2e-22 80.4 1.1 9.8e-22 78.1 1.1 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF563 PF04577.14 OIR58434.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Spo12 PF05032.12 OIR58435.1 - 0.00011 22.0 0.2 0.0002 21.2 0.2 1.5 1 0 0 1 1 1 1 Spo12 family SPC12 PF06645.13 OIR58436.1 - 3.6e-18 65.4 0.2 3.9e-18 65.3 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2370 PF10176.9 OIR58438.1 - 9.4e-08 32.0 3.2 3.8e-07 30.0 2.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) tRNA_U5-meth_tr PF05958.11 OIR58440.1 - 1.3e-19 70.4 0.0 5.4e-17 61.8 0.0 2.5 2 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 OIR58440.1 - 6.5e-13 48.7 0.1 2.1e-12 47.1 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OIR58440.1 - 4.6e-11 43.3 0.1 1.3e-10 41.8 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OIR58440.1 - 3.6e-09 36.4 0.0 6.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 OIR58440.1 - 8.4e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OIR58440.1 - 9.6e-07 29.4 0.3 2.9e-06 27.8 0.1 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OIR58440.1 - 1.2e-06 28.0 0.1 2.6e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OIR58440.1 - 4.6e-05 23.3 0.0 9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OIR58440.1 - 0.00017 21.6 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OIR58440.1 - 0.00092 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 OIR58440.1 - 0.00099 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 OIR58440.1 - 0.0013 18.5 1.5 0.029 14.1 1.5 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 OIR58440.1 - 0.0016 17.9 0.2 0.0027 17.2 0.2 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa PrmA PF06325.13 OIR58440.1 - 0.0018 17.7 0.2 0.0042 16.5 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 OIR58440.1 - 0.0022 18.7 0.1 0.006 17.3 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 OIR58440.1 - 0.0027 17.4 0.0 0.0048 16.6 0.0 1.7 1 1 0 1 1 1 1 DNA methylase NodS PF05401.11 OIR58440.1 - 0.0059 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 OIR58440.1 - 0.018 15.2 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.20 OIR58440.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 OIR58440.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PCMT PF01135.19 OIR58440.1 - 0.042 13.6 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DEAD PF00270.29 OIR58441.1 - 1.4e-39 135.7 0.0 2.4e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58441.1 - 1.7e-24 86.3 0.0 4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58441.1 - 1.2e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OIR58441.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 OIR58441.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 OIR58441.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 OIR58441.1 - 0.56 10.5 3.9 16 5.7 3.9 2.7 1 1 0 1 1 1 0 AAA domain Flavodoxin_1 PF00258.25 OIR58442.1 - 4.4e-24 85.3 0.0 1e-23 84.2 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OIR58442.1 - 7.8e-18 65.1 0.0 1.7e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 OIR58442.1 - 2.6e-17 63.1 0.0 3.8e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 OIR58442.1 - 0.00065 19.8 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain UPF0728 PF15092.6 OIR58442.1 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0728 Sec8_exocyst PF04048.14 OIR58443.1 - 0.00016 21.6 2.8 0.00016 21.6 2.8 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF489 PF04356.12 OIR58443.1 - 0.015 15.3 1.7 0.032 14.2 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF489) YkyA PF10368.9 OIR58443.1 - 0.058 13.1 8.7 0.21 11.2 8.7 2.0 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Csm2_III-A PF03750.13 OIR58443.1 - 0.074 13.9 3.0 0.38 11.6 3.0 2.2 1 0 0 1 1 1 0 Csm2 Type III-A BLOC1_2 PF10046.9 OIR58443.1 - 0.25 11.7 5.1 0.25 11.7 2.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MutS_III PF05192.18 OIR58443.1 - 0.3 11.3 2.9 0.94 9.7 2.8 2.0 1 1 0 1 1 1 0 MutS domain III FANCI_S3 PF14677.6 OIR58443.1 - 0.47 10.1 7.0 0.08 12.6 0.5 2.7 3 1 0 3 3 3 0 FANCI solenoid 3 CSN5_C PF18323.1 OIR58443.1 - 1.4 9.9 4.6 60 4.7 0.0 4.0 3 1 1 4 4 4 0 Cop9 signalosome subunit 5 C-terminal domain Spectrin PF00435.21 OIR58443.1 - 2.2 8.8 7.7 2 9.0 1.9 3.1 2 0 0 2 2 2 0 Spectrin repeat COG5 PF10392.9 OIR58443.1 - 2.8 8.1 8.0 0.55 10.4 3.5 2.2 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF948 PF06103.11 OIR58443.1 - 7.1 7.0 9.6 21 5.4 1.8 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Pex24p PF06398.11 OIR58444.1 - 5.7e-07 28.8 2.8 6.3e-07 28.7 1.9 1.5 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin DNA_pol_B_thumb PF14791.6 OIR58444.1 - 0.14 12.3 0.1 0.5 10.6 0.1 2.0 1 0 0 1 1 1 0 DNA polymerase beta thumb tRNA-synt_2 PF00152.20 OIR58445.1 - 5.2e-75 252.4 0.0 7.8e-75 251.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OIR58445.1 - 1.4e-10 41.0 0.0 3.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OIR58445.1 - 5.9e-07 29.2 0.1 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MSC PF09402.10 OIR58446.1 - 9.2e-31 107.5 3.8 2e-30 106.4 2.8 2.0 1 1 0 1 1 1 1 Man1-Src1p-C-terminal domain EAP30 PF04157.16 OIR58446.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family CTF_NFI PF00859.18 OIR58446.1 - 0.35 10.7 2.1 0.5 10.2 2.1 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region Adaptin_N PF01602.20 OIR58447.1 - 5.6e-70 236.4 0.0 6.5e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OIR58447.1 - 0.0072 16.4 0.0 4.5 7.3 0.0 3.5 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RRM_1 PF00076.22 OIR58448.1 - 6.5e-62 205.3 3.3 1.3e-18 66.6 0.4 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OIR58448.1 - 2.8e-06 27.1 0.0 2.1 8.2 0.0 4.5 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OIR58448.1 - 1.6e-05 24.9 9.2 0.0039 17.2 0.6 4.0 2 1 1 3 3 3 2 RNA binding motif RRM_5 PF13893.6 OIR58448.1 - 1.8e-05 24.3 0.5 0.43 10.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OIR58448.1 - 5.4e-05 23.2 0.7 4.9 7.3 0.0 4.8 4 0 0 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.6 OIR58448.1 - 0.0024 17.8 0.5 9 6.4 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 OIR58448.1 - 0.0026 17.9 0.4 1.3 9.3 0.0 3.2 4 0 0 4 4 4 1 BRCA1-associated protein 2 RL PF17797.1 OIR58448.1 - 0.0028 17.6 1.5 0.65 10.0 0.1 3.3 3 0 0 3 3 3 1 RL domain Calx-beta PF03160.14 OIR58448.1 - 0.065 13.4 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 Calx-beta domain DUF4523 PF15023.6 OIR58448.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) SET_assoc PF11767.8 OIR58448.1 - 0.1 12.3 1.4 1.6 8.4 0.1 3.1 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 OIR58448.1 - 0.16 12.2 0.0 6.5 7.0 0.0 2.9 3 0 0 3 3 3 0 RRM-like domain HSP20 PF00011.21 OIR58449.1 - 1.7e-08 34.6 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OIR58449.1 - 0.00095 18.7 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA MatB PF16449.5 OIR58449.1 - 0.21 11.4 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Fimbrillin MatB zinc_ribbon_10 PF10058.9 OIR58450.1 - 4.2e-12 45.6 1.6 7.1e-12 44.9 1.6 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF2207 PF09972.9 OIR58450.1 - 0.00079 18.3 2.2 0.001 18.0 2.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DZR PF12773.7 OIR58450.1 - 0.031 14.3 1.5 0.055 13.5 1.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon TNFR_c6 PF00020.18 OIR58450.1 - 0.039 14.4 0.8 0.16 12.4 0.0 2.1 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region DUF2681 PF10883.8 OIR58450.1 - 0.059 13.8 3.4 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) COQ7 PF03232.13 OIR58450.1 - 0.063 13.1 3.1 20 4.9 0.0 3.1 2 1 1 3 3 3 0 Ubiquinone biosynthesis protein COQ7 CT_C_D PF02682.16 OIR58450.1 - 0.12 12.1 1.0 0.57 9.9 0.1 2.1 1 1 1 2 2 2 0 Carboxyltransferase domain, subdomain C and D DUF21 PF01595.20 OIR58450.1 - 0.2 11.4 3.8 1.7 8.3 0.7 2.4 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain A2L_zn_ribbon PF08792.10 OIR58450.1 - 0.68 9.7 3.7 2 8.2 3.7 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 OIR58450.1 - 0.83 9.2 3.2 3 7.4 3.4 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding NuA4 PF09340.10 OIR58450.1 - 5.4 7.0 7.7 19 5.2 0.2 2.4 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Bac_small_YrzI PF09501.10 OIR58450.1 - 6 7.1 10.2 0.83 9.8 1.0 2.7 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Cyclin_N PF00134.23 OIR58451.1 - 2e-07 30.8 0.0 4.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain GAT PF03127.14 OIR58453.1 - 0.034 14.4 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 GAT domain ARID PF01388.21 OIR58454.1 - 0.0018 18.9 0.1 0.0039 17.8 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Gal4_dimer PF03902.13 OIR58455.1 - 0.09 12.9 0.3 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain Med31 PF05669.12 OIR58457.1 - 1.7e-27 95.2 1.1 1.9e-27 95.1 1.1 1.1 1 0 0 1 1 1 1 SOH1 Ribonuc_red_lgC PF02867.15 OIR58458.1 - 5.6e-184 612.5 0.0 7.1e-184 612.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OIR58458.1 - 3.8e-24 84.5 0.0 9.6e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OIR58458.1 - 4.4e-14 52.8 0.9 1.2e-13 51.4 0.9 1.8 1 0 0 1 1 1 1 ATP cone domain DUF1325 PF07039.11 OIR58459.1 - 0.00013 22.1 0.5 0.00033 20.8 0.2 2.0 1 1 0 1 1 1 1 SGF29 tudor-like domain PWWP PF00855.17 OIR58459.1 - 0.041 14.3 0.1 0.26 11.7 0.0 2.4 2 0 0 2 2 2 0 PWWP domain PC_rep PF01851.22 OIR58460.1 - 0.0011 19.3 1.8 6.9 7.3 0.0 4.3 5 0 0 5 5 5 2 Proteasome/cyclosome repeat PGM_PMM_I PF02878.16 OIR58461.1 - 4.7e-16 58.8 0.0 8.2e-07 28.8 0.0 2.9 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OIR58461.1 - 1.1e-08 35.1 0.2 3e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OIR58461.1 - 4.6e-05 23.6 0.3 9.6e-05 22.5 0.3 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF1325 PF07039.11 OIR58462.1 - 2.8e-17 63.0 0.0 6.1e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain TUDOR_5 PF18359.1 OIR58462.1 - 0.0053 16.4 0.2 0.015 14.9 0.2 1.8 1 1 0 1 1 1 1 Histone methyltransferase Tudor domain 1 LBR_tudor PF09465.10 OIR58462.1 - 0.24 11.2 1.0 0.55 10.1 0.2 2.1 2 1 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF3060 PF11259.8 OIR58463.1 - 0.00016 21.3 5.9 0.0057 16.3 0.1 4.3 2 2 2 4 4 4 1 Protein of unknown function (DUF3060) NTNH_C PF08470.10 OIR58463.1 - 0.072 13.0 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Kelch_6 PF13964.6 OIR58463.1 - 0.37 11.2 1.6 1.8 9.0 1.2 2.5 2 1 0 2 2 2 0 Kelch motif DUF3060 PF11259.8 OIR58464.1 - 0.0014 18.3 27.1 0.0025 17.5 2.1 5.0 3 2 1 4 4 4 3 Protein of unknown function (DUF3060) Proteasome PF00227.26 OIR58465.1 - 1.1e-29 103.3 0.1 1.3e-29 103.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR58465.1 - 2.3e-12 46.4 0.1 3.8e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MOZART1 PF12554.8 OIR58466.1 - 7.4e-14 51.3 0.6 8.2e-14 51.1 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.7 OIR58466.1 - 0.063 12.9 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Pkinase PF00069.25 OIR58467.1 - 3.3e-27 95.5 0.0 1.6e-26 93.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58467.1 - 1.8e-11 43.8 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR58467.1 - 1.6e-05 24.4 0.0 0.00032 20.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OIR58467.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BING4CT PF08149.11 OIR58468.1 - 7e-30 102.7 0.0 1.9e-28 98.1 0.0 2.6 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.32 OIR58468.1 - 2.5e-05 24.9 0.8 0.15 13.0 0.0 5.0 5 1 0 5 5 5 1 WD domain, G-beta repeat PQQ_2 PF13360.6 OIR58468.1 - 0.0027 17.3 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.14 OIR58468.1 - 0.031 13.3 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Peptidase_M24 PF00557.24 OIR58469.1 - 6.6e-49 166.4 0.0 9.6e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 OIR58469.1 - 3.6e-36 124.7 0.0 2.8e-35 121.8 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 OIR58469.1 - 6.3e-24 85.1 0.0 3.4e-20 73.0 0.0 2.9 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 OIR58469.1 - 1.2e-15 57.2 0.0 2.5e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Kinase-like PF14531.6 OIR58470.1 - 0.0068 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Kinase-like PIP49_C PF12260.8 OIR58470.1 - 0.17 11.5 20.3 0.072 12.7 3.2 4.2 1 1 3 4 4 4 0 Protein-kinase domain of FAM69 Pentapeptide_4 PF13599.6 OIR58470.1 - 1.4 9.2 12.5 0.71 10.1 1.2 3.6 1 1 3 4 4 4 0 Pentapeptide repeats (9 copies) Brix PF04427.18 OIR58471.1 - 8.7e-14 52.1 0.0 1.4e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Brix domain DUF1163 PF06651.11 OIR58471.1 - 0.0048 16.9 0.5 0.018 15.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1163) Vsr PF03852.15 OIR58471.1 - 0.042 13.7 0.4 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Sec1 PF00995.23 OIR58472.1 - 4.5e-94 316.7 0.0 5e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SMK-1 PF04802.15 OIR58473.1 - 0.00087 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 EF-hand_1 PF00036.32 OIR58474.1 - 1.4e-22 77.5 5.2 5.1e-09 35.0 1.9 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OIR58474.1 - 6.1e-19 68.3 1.8 1.8e-13 50.7 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OIR58474.1 - 1.5e-18 65.1 3.3 5.2e-05 22.9 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 OIR58474.1 - 2.8e-16 59.1 1.7 1.7e-11 43.8 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OIR58474.1 - 5.5e-11 41.4 6.8 4.7e-05 22.7 2.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 OIR58474.1 - 1.1e-08 35.2 0.0 6.3e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 OIR58474.1 - 3.3e-07 30.2 0.7 0.036 14.0 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OIR58474.1 - 0.00089 19.2 0.1 0.49 10.3 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein Endonuclease_5 PF04493.14 OIR58474.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Endonuclease V SHOCT PF09851.9 OIR58474.1 - 2.4 8.0 6.2 1.2 8.9 0.3 3.1 3 0 0 3 3 3 0 Short C-terminal domain DUF3060 PF11259.8 OIR58475.1 - 2.3e-06 27.2 14.9 0.0014 18.3 1.2 5.8 2 2 3 5 5 5 3 Protein of unknown function (DUF3060) DUF4176 PF13780.6 OIR58475.1 - 0.11 12.5 0.5 0.41 10.7 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4176) Reg_prop PF07494.11 OIR58475.1 - 2 8.9 3.7 14 6.3 0.0 4.1 6 0 0 6 6 6 0 Two component regulator propeller HSP90 PF00183.18 OIR58476.1 - 5.7e-192 639.2 21.2 7.2e-192 638.9 21.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OIR58476.1 - 2.2e-13 50.7 0.1 4.7e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OIR58476.1 - 2.5e-10 40.3 0.1 2.5e-10 40.3 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MecA PF05389.12 OIR58476.1 - 0.0061 16.2 0.6 0.0061 16.2 0.6 2.6 2 1 0 2 2 2 1 Negative regulator of genetic competence (MecA) RPN2_C PF18004.1 OIR58476.1 - 0.2 11.6 9.6 5 7.0 6.0 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4363 PF14276.6 OIR58476.1 - 2.1 8.5 12.4 2.4 8.3 5.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Pkinase PF00069.25 OIR58477.1 - 1.7e-11 44.0 0.8 2e-11 43.8 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain TadZ_N PF16968.5 OIR58477.1 - 0.034 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal Pkinase PF00069.25 OIR58478.1 - 8.3e-19 68.0 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58478.1 - 6.9e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR58478.1 - 0.00024 20.5 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OIR58478.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 OIR58478.1 - 0.12 11.9 0.1 15 5.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Gyro_capsid PF04162.12 OIR58478.1 - 0.15 10.5 0.0 1 7.7 0.0 1.9 2 0 0 2 2 2 0 Gyrovirus capsid protein (VP1) Pox_MCEL PF03291.16 OIR58479.1 - 1.4e-39 136.1 0.0 2.2e-39 135.5 0.0 1.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OIR58479.1 - 5e-10 40.0 0.0 8.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OIR58479.1 - 5.7e-09 36.6 0.0 9.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OIR58479.1 - 1.1e-05 26.0 0.0 1.8e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OIR58479.1 - 1.7e-05 24.6 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OIR58479.1 - 0.00028 20.3 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OIR58479.1 - 0.0013 18.5 0.0 0.0025 17.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Bromodomain PF00439.25 OIR58480.1 - 4.5e-17 61.9 0.0 1.3e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain DUF3458 PF11940.8 OIR58480.1 - 0.0031 17.9 0.2 0.013 16.0 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold DNA_ligase_A_M PF01068.21 OIR58482.1 - 1.4e-56 191.4 0.0 2.2e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OIR58482.1 - 8e-38 130.5 0.4 1.3e-37 129.8 0.4 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OIR58482.1 - 8.2e-26 90.5 0.2 3.9e-25 88.3 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OIR58482.1 - 0.00011 22.6 0.0 0.00018 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 OIR58482.1 - 0.0033 17.3 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain QIL1 PF15884.5 OIR58484.1 - 0.034 14.7 0.2 0.67 10.6 0.1 3.0 2 1 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 DUF1378 PF07125.11 OIR58484.1 - 1.2 9.4 4.0 10 6.4 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) UPF0449 PF15136.6 OIR58484.1 - 6.3 7.3 16.9 0.48 10.9 2.0 3.8 3 2 0 3 3 3 0 Uncharacterised protein family UPF0449 VHS PF00790.19 OIR58485.1 - 0.00059 19.7 0.3 0.0018 18.2 0.3 1.8 1 1 0 1 1 1 1 VHS domain Rhodanese_C PF12368.8 OIR58485.1 - 0.01 16.2 0.0 0.049 14.0 0.0 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal Pkinase PF00069.25 OIR58486.1 - 1.8e-18 66.9 0.0 4.5e-18 65.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 OIR58486.1 - 3.2e-06 27.3 0.1 0.0013 18.7 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OIR58486.1 - 0.00045 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 OIR58486.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR58486.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANTH PF07651.16 OIR58487.1 - 2.6e-35 121.8 0.2 2.7e-34 118.4 0.0 2.2 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 OIR58487.1 - 1.1e-20 74.4 1.8 1.1e-20 74.4 1.8 3.3 2 1 0 2 2 2 1 I/LWEQ domain DUF4382 PF14321.6 OIR58487.1 - 0.12 12.6 0.5 0.82 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) ALMT PF11744.8 OIR58487.1 - 0.61 8.9 10.1 1.3 7.7 10.1 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter PSP1 PF04468.12 OIR58488.1 - 1.9e-30 105.0 1.1 3.5e-30 104.1 1.1 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Urb2 PF10441.9 OIR58489.1 - 0.0099 15.8 0.5 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 Urb2/Npa2 family HSCB_C PF07743.13 OIR58489.1 - 0.17 12.4 4.3 3.5 8.2 0.2 3.2 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Yippee-Mis18 PF03226.14 OIR58490.1 - 1.1e-06 28.8 3.6 3e-06 27.4 3.6 1.8 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SEO_C PF14577.6 OIR58490.1 - 0.018 14.5 0.5 0.29 10.5 0.1 2.2 2 0 0 2 2 2 0 Sieve element occlusion C-terminus TEX12 PF15219.6 OIR58490.1 - 0.045 14.1 0.2 0.11 12.8 0.2 1.7 1 0 0 1 1 1 0 Testis-expressed 12 zinc_ribbon_12 PF11331.8 OIR58490.1 - 0.071 12.9 0.9 0.74 9.7 0.0 2.8 2 0 0 2 2 2 0 Probable zinc-ribbon domain CCDC53 PF10152.9 OIR58490.1 - 3.7 7.9 12.6 0.79 10.1 8.4 2.0 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex DWNN PF08783.11 OIR58491.1 - 4.3e-24 84.6 0.2 1.5e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 OIR58491.1 - 0.00034 20.4 1.4 0.00079 19.2 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OIR58491.1 - 0.0032 17.5 1.5 0.0032 17.5 1.5 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 OIR58491.1 - 0.015 15.0 2.9 0.056 13.2 0.6 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-RING_6 PF14835.6 OIR58491.1 - 0.033 14.1 3.4 0.059 13.3 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCHC_4 PF14392.6 OIR58491.1 - 0.16 11.7 3.1 0.27 11.0 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_3 PF13920.6 OIR58491.1 - 0.34 10.8 12.9 0.037 13.9 7.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1610 PF07754.11 OIR58491.1 - 1.7 8.7 8.0 6.6 6.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) HypA PF01155.19 OIR58491.1 - 1.9 8.6 9.7 29 4.7 0.1 3.2 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PHD PF00628.29 OIR58493.1 - 1.1e-05 25.3 6.4 2.6e-05 24.0 6.4 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OIR58493.1 - 0.0011 18.5 2.8 0.0011 18.5 2.8 2.0 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 OIR58493.1 - 0.0021 18.3 0.4 0.0021 18.3 0.4 2.1 2 1 0 2 2 2 1 PHD-like zinc-binding domain ING PF12998.7 OIR58493.1 - 0.017 15.7 0.1 0.045 14.3 0.1 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H_2 PF13832.6 OIR58493.1 - 0.11 12.7 6.2 0.19 11.9 4.5 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain SBDS PF01172.18 OIR58494.1 - 1.1e-24 86.3 0.1 3.8e-24 84.6 0.1 1.9 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 OIR58494.1 - 6e-18 64.9 0.4 8.8e-18 64.4 0.4 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain eIF-5_eIF-2B PF01873.17 OIR58494.1 - 0.017 15.0 1.3 0.024 14.5 0.1 2.0 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Fes1 PF08609.10 OIR58495.1 - 2.3e-09 38.0 0.3 4.5e-09 37.1 0.3 1.5 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 Ribosomal_L3 PF00297.22 OIR58498.1 - 2.5e-148 494.0 7.8 2.8e-148 493.8 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 WD40 PF00400.32 OIR58499.1 - 5.1e-31 106.2 7.2 9.8e-09 35.7 0.0 7.7 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58499.1 - 2.1e-14 53.6 0.0 4.5e-05 23.7 0.0 6.1 2 2 5 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OIR58499.1 - 2.1e-08 33.8 0.5 3.8e-08 33.0 0.5 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 OIR58499.1 - 0.00044 19.3 0.0 0.48 9.3 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 OIR58499.1 - 0.033 12.2 0.1 9.3 4.1 0.0 2.9 3 0 0 3 3 3 0 IKI3 family DUF4082 PF13313.6 OIR58499.1 - 0.16 12.1 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) PD40 PF07676.12 OIR58499.1 - 0.19 11.7 0.3 2.6 8.1 0.1 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF2116 PF09889.9 OIR58500.1 - 0.51 10.4 3.4 0.97 9.5 3.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Histone_H2A_C PF16211.5 OIR58501.1 - 8e-18 63.9 1.5 8e-18 63.9 1.5 1.5 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 OIR58501.1 - 4e-16 59.6 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OIR58501.1 - 4.3e-08 33.3 0.0 5.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 OIR58501.1 - 0.01 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) DNA_topoisoIV PF00521.20 OIR58502.1 - 1.1e-124 416.6 0.0 2e-124 415.7 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OIR58502.1 - 2.7e-47 160.2 2.0 2.7e-47 160.2 2.0 2.0 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OIR58502.1 - 4.4e-20 71.9 0.2 4.4e-20 71.9 0.2 1.9 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 OIR58502.1 - 1.8e-11 44.5 0.0 5.3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OIR58502.1 - 2.4e-08 34.1 0.0 1e-07 32.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain His_Me_b4a2 PF18275.1 OIR58502.1 - 4.9 7.3 5.1 14 5.8 1.1 2.9 3 0 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain Helicase_C_2 PF13307.6 OIR58503.1 - 0.0075 16.5 0.0 0.054 13.7 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DUF3060 PF11259.8 OIR58504.1 - 4.9e-10 38.9 22.8 1.8e-06 27.5 2.0 5.6 5 1 0 5 5 5 4 Protein of unknown function (DUF3060) Aa_trans PF01490.18 OIR58505.1 - 3e-55 187.6 22.1 3.5e-55 187.4 22.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein E1_DerP2_DerF2 PF02221.15 OIR58506.1 - 2.2e-08 34.6 0.0 2.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 ML domain UFC1 PF08694.11 OIR58506.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Swi3 PF07962.12 OIR58507.1 - 1.6e-12 47.2 0.0 2.4e-12 46.7 0.0 1.3 1 1 0 1 1 1 1 Replication Fork Protection Component Swi3 Gar1 PF04410.14 OIR58508.1 - 8.1e-27 93.9 0.0 9.3e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DEAD PF00270.29 OIR58509.1 - 4e-34 117.9 0.0 5.8e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58509.1 - 5.7e-25 87.8 0.0 1.6e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58509.1 - 2.7e-06 27.5 0.0 4.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OIR58509.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OIR58509.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.6 OIR58509.1 - 0.02 15.1 0.6 0.053 13.7 0.0 2.0 3 0 0 3 3 3 0 Helicase C-terminal domain Pox_D2 PF04701.13 OIR58509.1 - 0.16 12.1 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Pox virus D2 protein PAP_assoc PF03828.19 OIR58510.1 - 0.00059 20.0 0.1 0.0026 17.9 0.1 2.1 1 1 1 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OIR58510.1 - 0.09 13.1 0.0 0.29 11.5 0.0 1.9 1 1 0 1 1 1 0 Nucleotidyltransferase domain TruB_N PF01509.18 OIR58511.1 - 8.2e-40 136.6 0.2 1.2e-39 136.1 0.2 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Methyltransf_11 PF08241.12 OIR58511.1 - 0.017 15.8 0.1 0.052 14.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RRS1 PF04939.12 OIR58512.1 - 1.2e-22 80.5 0.3 1.6e-22 80.1 0.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PCMT PF01135.19 OIR58513.1 - 3.3e-10 40.1 0.0 4.3e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PapC_N PF13954.6 OIR58513.1 - 0.2 11.7 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 PapC N-terminal domain DNA_pol_B PF00136.21 OIR58514.1 - 8.9e-139 463.1 0.0 1.3e-138 462.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OIR58514.1 - 5.5e-66 223.0 0.3 5.5e-66 223.0 0.3 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OIR58514.1 - 1.3e-17 64.0 11.0 2.3e-17 63.2 7.9 2.5 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 OIR58514.1 - 2e-05 23.7 1.1 0.00034 19.6 1.1 2.3 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 OIR58514.1 - 0.0013 18.7 0.4 0.037 14.0 0.2 3.1 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 OIR58514.1 - 0.0023 17.7 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_exo2 PF10108.9 OIR58514.1 - 0.068 12.8 0.1 0.18 11.5 0.1 1.6 1 1 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF2614 PF11023.8 OIR58514.1 - 0.23 11.6 1.3 0.53 10.4 0.2 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain DZR PF12773.7 OIR58514.1 - 0.49 10.5 6.4 1.7 8.7 6.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon CH PF00307.31 OIR58515.1 - 2.9e-72 239.8 0.1 4.4e-20 71.9 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OIR58515.1 - 7.3e-09 35.4 0.0 0.0017 18.2 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain GTP_EFTU PF00009.27 OIR58517.1 - 2e-51 174.3 0.3 3.3e-51 173.6 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OIR58517.1 - 6.2e-42 142.4 0.0 1.4e-41 141.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OIR58517.1 - 1.3e-10 41.5 1.7 1.3e-10 41.5 1.7 2.5 3 1 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OIR58517.1 - 0.0006 19.9 0.2 0.02 14.9 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OIR58517.1 - 0.44 10.3 1.5 12 5.8 0.2 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU_D4 PF14578.6 OIR58517.1 - 0.99 9.3 4.5 0.67 9.9 1.5 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 VirArc_Nuclease PF12187.8 OIR58518.1 - 0.0059 16.2 0.0 0.1 12.1 0.0 2.0 1 1 1 2 2 2 2 Viral/Archaeal nuclease Glycolytic PF00274.19 OIR58519.1 - 4.2e-148 492.8 0.0 4.7e-148 492.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ZT_dimer PF16916.5 OIR58519.1 - 0.21 11.8 0.1 0.49 10.6 0.0 1.6 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter zf-C3HC4_3 PF13920.6 OIR58520.1 - 2.6e-05 24.0 8.9 5.9e-05 22.8 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR58520.1 - 0.00038 20.2 5.3 0.0013 18.5 5.3 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OIR58520.1 - 0.00084 19.6 9.0 0.0025 18.1 9.0 1.9 1 0 0 1 1 1 1 Ring finger domain BAF250_C PF12031.8 OIR58520.1 - 0.02 14.2 0.2 2.2 7.5 0.0 2.6 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa AbiH PF14253.6 OIR58520.1 - 0.032 14.1 0.3 0.059 13.2 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Acetyltransf_CG PF14542.6 OIR58520.1 - 0.06 13.5 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-RING_4 PF14570.6 OIR58520.1 - 0.085 12.7 11.9 0.031 14.1 6.9 2.6 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Reg_prop PF07494.11 OIR58520.1 - 0.14 12.4 1.4 1.2e+02 3.4 0.0 4.8 5 0 0 5 5 5 0 Two component regulator propeller FYVE_2 PF02318.16 OIR58520.1 - 0.61 10.3 7.9 0.28 11.4 3.6 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger ANAPC4_WD40 PF12894.7 OIR58521.1 - 3.4e-06 27.3 0.0 0.00023 21.4 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OIR58521.1 - 0.01 16.7 0.2 0.85 10.6 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat RRM_1 PF00076.22 OIR58522.1 - 1.5e-21 76.0 0.0 1.7e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OIR58522.1 - 1.4e-05 25.1 0.0 2.3e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_8 PF11835.8 OIR58522.1 - 0.17 12.1 0.0 0.2 11.9 0.0 1.3 1 1 0 1 1 1 0 RRM-like domain Ribosomal_L7Ae PF01248.26 OIR58523.1 - 5.5e-17 61.3 0.4 6.6e-17 61.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family X8 PF07983.13 OIR58523.1 - 0.1 13.3 0.1 0.16 12.7 0.1 1.4 1 0 0 1 1 1 0 X8 domain RRM_1 PF00076.22 OIR58525.1 - 4.6e-28 96.8 0.6 1.8e-13 50.1 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OIR58525.1 - 1.5e-05 25.0 0.1 0.16 12.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif DNA_ligase_IV PF11411.8 OIR58525.1 - 0.00077 19.5 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 DNA ligase IV PHM7_cyt PF14703.6 OIR58525.1 - 0.0076 16.5 6.1 8 6.7 0.0 4.0 3 2 2 5 5 5 2 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 OIR58525.1 - 0.013 15.3 1.3 2.7 7.8 0.1 3.4 2 2 2 4 4 4 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 OIR58525.1 - 0.021 14.9 3.7 0.047 13.7 0.1 2.9 2 2 1 3 3 3 0 RNA binding motif GlcNAc-1_reg PF18440.1 OIR58525.1 - 0.035 14.3 1.6 0.38 11.0 0.4 2.8 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain Limkain-b1 PF11608.8 OIR58525.1 - 0.073 13.2 0.2 1 9.5 0.0 3.0 2 1 1 3 3 3 0 Limkain b1 DCP1 PF06058.13 OIR58526.1 - 2.7e-13 49.9 0.0 3.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DUF1971 PF09313.11 OIR58526.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Ribosomal_S9 PF00380.19 OIR58527.1 - 2.1e-29 102.5 0.1 2.4e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Dala_Dala_lig_C PF07478.13 OIR58527.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Ribosomal_L13e PF01294.18 OIR58528.1 - 1.2e-42 145.8 5.9 1.7e-42 145.3 5.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e APO_RNA-bind PF05634.11 OIR58528.1 - 0.056 12.8 1.6 0.085 12.2 1.6 1.3 1 0 0 1 1 1 0 APO RNA-binding eIF-1a PF01176.19 OIR58529.1 - 4.6e-13 48.8 0.2 9e-13 47.8 0.1 1.5 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 PIG-L PF02585.17 OIR58530.1 - 1.4e-20 74.2 0.0 2.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase AhpC-TSA PF00578.21 OIR58531.1 - 1.3e-33 115.6 0.0 2e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OIR58531.1 - 2.6e-12 46.7 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OIR58531.1 - 2e-08 34.0 0.1 4.2e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Cpn60_TCP1 PF00118.24 OIR58532.1 - 2.4e-143 478.3 0.5 2.8e-143 478.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Trypan_PARP PF05887.11 OIR58533.1 - 0.028 14.4 0.1 0.041 13.9 0.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 OIR58533.1 - 0.04 13.5 4.7 0.053 13.1 4.7 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RVT_1 PF00078.27 OIR58534.1 - 6.3e-25 88.0 0.1 1.1e-24 87.2 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OIR58534.1 - 2.3e-11 43.6 0.0 5.8e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OIR58534.1 - 2.9e-07 30.7 0.0 1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase mCpol PF18182.1 OIR58534.1 - 0.61 10.4 3.3 55 4.1 0.1 4.6 3 1 2 5 5 5 0 minimal CRISPR polymerase domain Myb_DNA-binding PF00249.31 OIR58535.1 - 4.1e-06 26.9 0.0 0.051 13.8 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OIR58535.1 - 5.4e-05 23.4 0.0 0.1 12.8 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain V_ATPase_I PF01496.19 OIR58536.1 - 1.6e-200 668.0 5.3 4.8e-199 663.2 5.3 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family SYCE1 PF15233.6 OIR58536.1 - 0.014 15.5 2.8 0.87 9.6 0.5 2.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Peptidase_M50 PF02163.22 OIR58536.1 - 0.014 14.6 0.1 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M50 Telethonin PF09470.10 OIR58536.1 - 0.015 15.2 0.2 0.053 13.4 0.1 1.9 2 0 0 2 2 2 0 Telethonin protein DUF5344 PF17279.2 OIR58536.1 - 0.03 14.9 2.5 0.093 13.3 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) SlyX PF04102.12 OIR58536.1 - 0.062 13.9 9.8 0.28 11.8 0.3 3.4 2 1 1 3 3 3 0 SlyX DUF4577 PF15145.6 OIR58536.1 - 0.11 12.6 0.3 18 5.4 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Sfi1_C PF10638.9 OIR58536.1 - 0.15 12.8 0.1 0.34 11.7 0.1 1.5 1 0 0 1 1 1 0 Spindle body associated protein C-terminus Lebercilin PF15619.6 OIR58536.1 - 0.34 10.5 9.5 9.1 5.9 4.7 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 OIR58536.1 - 0.74 10.3 5.8 7 7.2 2.1 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 HSBP1 PF06825.12 OIR58536.1 - 0.84 9.5 6.3 5 7.1 0.5 3.4 3 1 0 3 3 3 0 Heat shock factor binding protein 1 MAD PF05557.13 OIR58536.1 - 1.5 7.1 10.6 0.17 10.2 2.5 2.4 3 0 0 3 3 3 0 Mitotic checkpoint protein Ribosomal_L32e PF01655.18 OIR58537.1 - 5.1e-42 142.7 0.8 6.3e-42 142.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Tox-MPTase2 PF15638.6 OIR58537.1 - 0.0026 17.6 0.1 0.0029 17.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase toxin 2 SRP19 PF01922.17 OIR58538.1 - 1.1e-15 58.4 0.1 1.3e-15 58.1 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein Pet100 PF09803.9 OIR58538.1 - 0.21 12.1 1.7 0.28 11.7 0.3 1.7 2 0 0 2 2 2 0 Pet100 CS PF04969.16 OIR58539.1 - 7.8e-18 65.3 0.9 1.3e-17 64.6 0.9 1.4 1 0 0 1 1 1 1 CS domain Clathrin PF00637.20 OIR58540.1 - 6e-59 198.0 0.0 4.8e-16 58.9 0.0 8.2 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OIR58540.1 - 5.8e-20 71.0 0.0 1.6e-19 69.5 0.0 1.9 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 OIR58540.1 - 2.3e-05 24.5 0.0 0.002 18.3 0.0 2.7 2 0 0 2 2 2 1 Clathrin propeller repeat Vps39_1 PF10366.9 OIR58540.1 - 0.00045 20.5 2.4 8.3 6.8 0.0 6.0 5 1 1 6 6 6 1 Vacuolar sorting protein 39 domain 1 UCH PF00443.29 OIR58541.1 - 2.7e-43 148.3 0.1 4.1e-43 147.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR58541.1 - 3.8e-18 66.2 0.0 1.5e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OIR58541.1 - 3.2e-13 49.9 0.6 3e-11 43.4 0.0 3.3 3 2 0 3 3 3 1 Ubiquitin-specific protease C-terminal DUF1499 PF07386.11 OIR58541.1 - 0.061 13.9 0.2 1 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1499) Yip1 PF04893.17 OIR58542.1 - 9.4e-10 38.5 7.2 1.3e-09 38.1 7.2 1.2 1 0 0 1 1 1 1 Yip1 domain YiiD_C PF09500.10 OIR58542.1 - 0.065 13.1 0.0 5.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF2207 PF09972.9 OIR58542.1 - 3.6 6.2 6.6 23 3.6 6.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ras PF00071.22 OIR58543.1 - 3.7e-42 143.7 0.0 4.3e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR58543.1 - 4.8e-17 62.3 0.0 6.9e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OIR58543.1 - 7e-06 25.6 0.0 9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OIR58543.1 - 0.00021 21.4 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OIR58543.1 - 0.0003 20.7 0.0 0.093 12.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OIR58543.1 - 0.0026 17.2 0.0 0.0032 16.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 OIR58543.1 - 0.0084 16.5 0.0 0.023 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 OIR58543.1 - 0.012 15.6 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 OIR58543.1 - 0.012 15.9 0.0 0.033 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 OIR58543.1 - 0.014 14.9 0.0 0.07 12.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.18 OIR58543.1 - 0.058 13.1 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 OIR58543.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 OIR58543.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 OIR58543.1 - 0.15 11.8 0.0 1.2 8.9 0.0 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 OIR58543.1 - 0.16 11.7 0.2 0.26 11.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OIR58543.1 - 0.2 12.1 0.0 3 8.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter GDP_Man_Dehyd PF16363.5 OIR58544.1 - 5.2e-53 180.6 0.0 6.3e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OIR58544.1 - 1.7e-49 168.5 0.0 2e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OIR58544.1 - 1e-18 67.3 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OIR58544.1 - 1.8e-17 63.4 0.0 1.6e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 OIR58544.1 - 1.9e-15 56.8 0.0 2.6e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 OIR58544.1 - 7e-11 41.9 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OIR58544.1 - 1.9e-09 37.7 0.0 3.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OIR58544.1 - 1e-07 31.4 0.3 1e-05 24.8 0.3 2.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OIR58544.1 - 2.1e-07 31.0 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 OIR58544.1 - 3.8e-06 26.6 0.0 6.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 OIR58544.1 - 1.5e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OIR58544.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 OIR58544.1 - 0.0053 16.0 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OIR58544.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 OIR58544.1 - 0.034 14.4 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OIR58544.1 - 0.098 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Filamin PF00630.19 OIR58545.1 - 0.11 13.4 0.0 0.52 11.2 0.0 2.2 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF4320 PF14208.6 OIR58545.1 - 0.19 11.8 1.7 3.9 7.6 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) DUF5601 PF18151.1 OIR58546.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) ATP-synt_E_2 PF08112.11 OIR58547.1 - 0.00031 20.9 1.9 0.00068 19.9 1.9 1.6 1 1 0 1 1 1 1 ATP synthase epsilon subunit Retrotrans_gag PF03732.17 OIR58547.1 - 0.027 14.7 1.5 1.4 9.2 0.1 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein DUF4456 PF14644.6 OIR58547.1 - 0.088 12.5 6.3 0.11 12.2 6.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4456) Condensin2nSMC PF12422.8 OIR58547.1 - 0.18 11.9 1.7 0.31 11.2 1.7 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit CCDC-167 PF15188.6 OIR58547.1 - 2.8 8.3 9.6 0.36 11.2 5.4 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4011 PF13195.6 OIR58547.1 - 3.7 7.5 7.9 8.3 6.3 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) RabGAP-TBC PF00566.18 OIR58548.1 - 1.2e-40 139.5 0.0 1.9e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 OIR58548.1 - 6.4e-22 77.6 0.5 3.3e-12 46.3 0.1 2.6 2 0 0 2 2 2 2 GRAM domain VAPB_antitox PF02697.14 OIR58548.1 - 0.28 12.0 2.5 0.33 11.8 0.1 2.4 3 0 0 3 3 3 0 Putative antitoxin Med29 PF11568.8 OIR58549.1 - 0.011 16.0 0.8 0.011 16.0 0.8 1.4 2 0 0 2 2 2 0 Mediator complex subunit 29 putAbiC PF16872.5 OIR58549.1 - 0.022 15.4 0.1 0.048 14.3 0.1 1.5 1 0 0 1 1 1 0 Putative phage abortive infection protein SKA2 PF16740.5 OIR58549.1 - 0.043 13.6 5.1 0.59 9.9 1.1 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 MSC PF09402.10 OIR58549.1 - 0.088 12.3 1.0 0.11 12.0 1.0 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PspB PF06667.12 OIR58549.1 - 2.3 8.3 5.5 3.9 7.6 0.3 2.7 3 0 0 3 3 3 0 Phage shock protein B Mad3_BUB1_I PF08311.12 OIR58550.1 - 2.4e-28 98.6 0.1 4.1e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 OIR58550.1 - 4.3e-07 30.1 0.0 8.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase PF00069.25 OIR58550.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain TPR_14 PF13428.6 OIR58550.1 - 0.14 13.0 0.3 0.87 10.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyclin_N PF00134.23 OIR58551.1 - 2.6e-09 36.9 0.0 3.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OIR58551.1 - 4.4e-06 27.1 0.1 6.2e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Cyclin Spy1 PF11357.8 OIR58551.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Cell cycle regulatory protein RHH_4 PF13467.6 OIR58551.1 - 0.12 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain RRN3 PF05327.11 OIR58553.1 - 9.4e-12 44.3 9.0 4e-08 32.3 2.0 3.2 1 1 1 3 3 3 3 RNA polymerase I specific transcription initiation factor RRN3 Sedlin_N PF04628.13 OIR58554.1 - 7.6e-25 87.5 0.1 8.8e-25 87.3 0.1 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 OIR58554.1 - 3.1e-07 30.4 0.1 4.9e-07 29.8 0.1 1.3 1 1 0 1 1 1 1 Sybindin-like family TFIID_NTD2 PF04494.15 OIR58555.1 - 4.3e-31 107.8 5.6 7.4e-31 107.1 5.6 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 OIR58555.1 - 4.7e-29 100.0 14.1 8.9e-07 29.5 0.6 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58555.1 - 6.6e-08 32.8 0.0 0.014 15.7 0.0 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OIR58555.1 - 1.1e-05 24.3 0.0 0.032 12.9 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OIR58555.1 - 0.0065 15.8 0.0 0.23 10.8 0.0 3.2 3 1 2 5 5 5 1 WD40-like domain PD40 PF07676.12 OIR58555.1 - 0.079 12.9 1.0 32 4.6 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat G-alpha PF00503.20 OIR58556.1 - 2e-119 398.9 0.3 2.4e-119 398.6 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OIR58556.1 - 2.5e-17 62.9 2.7 1.6e-11 44.0 0.1 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 OIR58556.1 - 0.00074 19.7 0.1 1.6 8.9 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OIR58556.1 - 0.0016 17.9 1.1 0.31 10.4 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OIR58556.1 - 0.0032 17.5 0.0 0.36 10.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OIR58556.1 - 0.014 14.7 0.1 0.042 13.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family TniB PF05621.11 OIR58556.1 - 0.021 14.3 0.1 0.054 12.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein GTP_EFTU PF00009.27 OIR58556.1 - 0.046 13.3 0.2 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 OIR58556.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain EMP24_GP25L PF01105.24 OIR58557.1 - 2.2e-18 66.8 0.1 2.8e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Fijivirus_P9-2 PF06837.11 OIR58557.1 - 0.036 13.5 0.2 0.054 13.0 0.2 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein PCI PF01399.27 OIR58558.1 - 1.1e-11 45.1 0.7 2.6e-11 44.0 0.2 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 OIR58558.1 - 0.00047 20.1 0.1 0.0014 18.6 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR58558.1 - 0.0027 18.0 0.1 0.0084 16.4 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OIR58558.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OIR58558.1 - 0.0055 16.5 0.1 0.015 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OIR58558.1 - 0.017 15.0 0.1 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OIR58558.1 - 0.024 15.3 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 OIR58558.1 - 0.025 14.6 0.1 0.07 13.2 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OIR58558.1 - 0.13 13.1 0.0 0.32 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_C13 PF01650.18 OIR58559.1 - 1.1e-36 126.7 0.0 1.3e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C13 family LAP1C PF05609.12 OIR58560.1 - 0.025 13.7 7.7 0.046 12.8 7.7 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) EVI2A PF05399.11 OIR58560.1 - 0.25 10.9 11.2 0.022 14.4 4.0 2.3 2 1 1 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) DUF4366 PF14283.6 OIR58560.1 - 4.2 7.4 14.8 5.7e+02 0.5 14.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SDA1 PF05285.12 OIR58560.1 - 4.3 6.7 19.3 6.8 6.0 19.3 1.3 1 0 0 1 1 1 0 SDA1 Plasmodium_Vir PF05795.11 OIR58560.1 - 4.4 6.6 12.1 13 5.1 12.1 1.8 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 OIR58560.1 - 6.1 5.5 9.1 9.5 4.9 9.1 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OIR58560.1 - 9.9 5.9 14.2 19 5.0 14.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIID_20kDa PF03847.13 OIR58563.1 - 4.5e-10 39.9 0.0 7.7e-10 39.1 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 OIR58563.1 - 0.04 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TIP49 PF06068.13 OIR58565.1 - 6.7e-135 449.8 1.1 8.2e-135 449.5 1.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OIR58565.1 - 1e-18 67.2 1.3 2.1e-18 66.2 0.3 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OIR58565.1 - 2.1e-09 37.9 0.6 4e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OIR58565.1 - 3.3e-09 36.7 0.1 1.9e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OIR58565.1 - 1.4e-07 31.5 0.1 0.022 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OIR58565.1 - 1.1e-05 25.9 0.1 0.0033 17.8 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OIR58565.1 - 2.3e-05 24.7 0.2 0.2 11.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OIR58565.1 - 0.0018 17.9 0.2 0.0037 16.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OIR58565.1 - 0.0019 17.9 0.4 0.34 10.6 0.1 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 OIR58565.1 - 0.003 17.1 0.1 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 OIR58565.1 - 0.0051 16.8 0.2 0.82 9.7 0.1 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.6 OIR58565.1 - 0.0055 16.9 0.2 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OIR58565.1 - 0.0062 15.9 0.2 0.21 11.0 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OIR58565.1 - 0.0081 16.2 0.1 0.027 14.5 0.1 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 OIR58565.1 - 0.0098 16.2 1.4 0.18 12.1 1.4 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OIR58565.1 - 0.021 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OIR58565.1 - 0.029 14.4 0.0 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OIR58565.1 - 0.037 13.5 1.7 0.06 12.8 0.4 1.9 2 0 0 2 2 2 0 PhoH-like protein SicP-binding PF09119.10 OIR58565.1 - 0.037 14.0 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 SicP binding Zeta_toxin PF06414.12 OIR58565.1 - 0.058 12.7 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 OIR58565.1 - 0.065 13.8 0.1 0.18 12.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OIR58565.1 - 0.084 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 OIR58565.1 - 0.089 12.7 0.2 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase CbiA PF01656.23 OIR58565.1 - 0.11 12.6 0.1 0.53 10.3 0.1 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_32 PF13654.6 OIR58565.1 - 0.19 10.5 1.3 3.5 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Polysacc_deac_1 PF01522.21 OIR58566.1 - 4.7e-06 26.5 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase FancD2 PF14631.6 OIR58568.1 - 0.021 12.3 0.0 0.42 8.0 0.0 2.1 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease Helicase_C_2 PF13307.6 OIR58568.1 - 0.15 12.2 0.1 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Helicase C-terminal domain Cpn60_TCP1 PF00118.24 OIR58569.1 - 6e-129 430.9 5.2 6.8e-129 430.7 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HMGL-like PF00682.19 OIR58569.1 - 0.018 14.6 1.4 5 6.6 0.1 3.0 3 0 0 3 3 3 0 HMGL-like FliG_N PF14842.6 OIR58569.1 - 0.76 10.4 3.9 1.1 9.9 0.4 3.1 3 1 0 3 3 3 0 FliG N-terminal domain TLD PF07534.16 OIR58570.1 - 4.2e-23 82.1 0.6 6.8e-23 81.4 0.6 1.4 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 OIR58570.1 - 6.5e-07 29.2 6.2 2e-06 27.6 6.2 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HhH-GPD PF00730.25 OIR58571.1 - 5.5e-14 52.5 0.0 7.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OIR58571.1 - 2.4e-07 30.3 0.0 5.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OIR58571.1 - 0.027 15.1 0.0 0.18 12.5 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 OIR58571.1 - 0.054 13.8 8.3 0.098 13.0 8.3 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Mannosyl_trans2 PF04188.13 OIR58572.1 - 1.1e-40 140.3 31.1 3.8e-39 135.2 31.1 2.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) TLD PF07534.16 OIR58573.1 - 2.3e-28 99.2 0.2 2.7e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 TLD UDPG_MGDP_dh_N PF03721.14 OIR58574.1 - 7.4e-56 188.7 0.1 1.2e-55 188.0 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OIR58574.1 - 9.3e-32 109.6 0.1 3.9e-31 107.6 0.0 2.0 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OIR58574.1 - 4.6e-29 100.5 0.0 9.9e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF2226 PF09987.9 OIR58574.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) NAD_binding_2 PF03446.15 OIR58574.1 - 0.033 14.3 0.5 2.5 8.3 0.1 2.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OIR58574.1 - 0.09 12.4 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Use1 PF09753.9 OIR58575.1 - 9.4e-12 45.2 0.9 9.9e-12 45.1 0.9 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2721 PF11026.8 OIR58575.1 - 0.015 15.2 0.2 0.022 14.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DASH_Spc34 PF08657.10 OIR58575.1 - 0.017 14.9 3.5 0.02 14.7 3.5 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF3675 PF12428.8 OIR58575.1 - 0.13 12.8 0.2 0.22 12.1 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) EMC3_TMCO1 PF01956.16 OIR58575.1 - 0.13 12.0 1.4 0.15 11.8 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Mgr1 PF08602.10 OIR58575.1 - 0.17 10.7 2.8 0.2 10.4 2.8 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit F-actin_cap_A PF01267.17 OIR58576.1 - 9.8e-15 54.7 0.0 1.1e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit RRM_1 PF00076.22 OIR58577.1 - 5e-19 67.9 0.1 1.2e-18 66.7 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OIR58577.1 - 0.00038 20.5 0.0 0.0014 18.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OIR58577.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Cnd2 PF05786.14 OIR58578.1 - 1.4e-59 202.6 12.7 1.5e-48 166.1 0.4 4.4 2 2 2 4 4 4 3 Condensin complex subunit 2 CNDH2_N PF06278.11 OIR58578.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SMC_ScpA PF02616.14 OIR58578.1 - 0.026 14.4 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Segregation and condensation protein ScpA Focadhesin PF11229.8 OIR58578.1 - 0.086 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Focadhesin Lactamase_B_2 PF12706.7 OIR58579.1 - 2.6e-14 53.2 0.0 4.3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OIR58579.1 - 4e-12 45.6 0.0 1.6e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 OIR58579.1 - 2.6e-09 37.4 0.1 5.8e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 OIR58579.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain PDEase_II PF02112.15 OIR58579.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II DUF1015 PF06245.11 OIR58579.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) EF1_GNE PF00736.19 OIR58580.1 - 4.7e-32 110.0 0.7 9.1e-32 109.1 0.7 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OIR58580.1 - 6.9e-10 39.2 2.5 6.9e-10 39.2 2.5 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 OIR58580.1 - 0.026 14.7 0.0 0.07 13.3 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3701 PF12482.8 OIR58580.1 - 0.075 13.1 0.0 11 6.2 0.0 2.7 3 0 0 3 3 3 0 Phage integrase protein TFIIS_C PF01096.18 OIR58581.1 - 6.3e-20 70.8 5.1 6.3e-20 70.8 5.1 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OIR58581.1 - 0.0023 17.8 2.3 0.0023 17.8 2.3 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Auto_anti-p27 PF06677.12 OIR58581.1 - 0.013 15.6 10.4 0.45 10.7 0.7 2.9 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Baculo_LEF5_C PF11792.8 OIR58581.1 - 0.015 15.0 1.7 0.033 13.8 1.7 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.7 OIR58581.1 - 0.019 14.9 1.7 0.019 14.9 1.7 3.2 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Cript PF10235.9 OIR58581.1 - 0.092 13.3 0.9 0.092 13.3 0.9 2.5 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT PhnA_Zn_Ribbon PF08274.12 OIR58581.1 - 0.39 10.7 18.8 3.4 7.7 0.4 4.2 4 0 0 4 4 4 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 OIR58581.1 - 1.7 8.6 13.9 3.6 7.6 0.9 4.0 4 0 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 OIR58581.1 - 3 8.0 20.5 2.4 8.3 3.9 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Elf1 PF05129.13 OIR58581.1 - 4.1 7.5 11.5 3.2 7.9 2.7 2.3 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 OIR58581.1 - 4.8 7.4 19.7 1.4 9.1 0.1 3.9 3 1 0 3 3 3 0 Zinc ribbon domain Rubredoxin PF00301.20 OIR58581.1 - 6.5 6.9 12.4 9 6.4 0.1 3.9 4 0 0 4 4 4 0 Rubredoxin ALMS_repeat PF18727.1 OIR58582.1 - 0.064 13.2 0.1 2.7 8.0 0.1 2.6 1 1 2 3 3 3 0 Alstrom syndrome repeat RNA_pol_L_2 PF13656.6 OIR58583.1 - 1.1e-17 63.5 0.1 1.6e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OIR58583.1 - 0.047 13.1 0.0 0.075 12.5 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_hydro_19 PF00182.19 OIR58586.1 - 6.8e-21 75.2 0.7 1.2e-13 51.5 0.3 2.8 1 1 1 2 2 2 2 Chitinase class I Mucin PF01456.17 OIR58586.1 - 0.043 13.8 2.6 0.069 13.1 2.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.17 OIR58586.1 - 7.9 5.1 5.8 10 4.7 5.8 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OIR58586.1 - 8.5 5.0 9.3 11 4.7 9.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 tRNA-synt_1c PF00749.21 OIR58587.1 - 5.1e-106 354.1 0.0 6.8e-106 353.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OIR58587.1 - 6.6e-23 81.5 0.0 1.2e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Lactamase_B_6 PF16661.5 OIR58588.1 - 2.8e-29 101.9 0.1 4.4e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OIR58588.1 - 5.3e-13 49.5 0.1 2.8e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OIR58588.1 - 7.8e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 OIR58588.1 - 0.0013 18.0 0.2 0.0043 16.3 0.1 1.8 2 0 0 2 2 2 1 Putative beta-lactamase-like family Lactamase_B PF00753.27 OIR58588.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily HeH PF12949.7 OIR58588.1 - 0.44 10.3 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 HeH/LEM domain RNA_pol_Rpb1_1 PF04997.12 OIR58589.1 - 3.1e-84 283.0 0.7 5.3e-84 282.2 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OIR58589.1 - 2.7e-80 269.7 1.3 2.7e-80 269.7 1.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OIR58589.1 - 3e-69 232.5 0.0 7.3e-69 231.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OIR58589.1 - 2.4e-30 105.5 0.0 5.3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OIR58589.1 - 3.7e-21 75.1 0.1 1e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 OIR58589.1 - 3.3 8.0 6.2 0.4 11.0 1.2 2.0 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNase_PH PF01138.21 OIR58590.1 - 4.3e-09 37.0 0.0 8.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NPV_P10 PF05531.12 OIR58591.1 - 0.0006 20.2 4.0 0.024 15.1 0.1 2.6 2 2 0 2 2 2 1 Nucleopolyhedrovirus P10 protein GIT1_C PF12205.8 OIR58591.1 - 0.00072 19.7 2.1 0.28 11.3 0.2 2.3 2 0 0 2 2 2 2 G protein-coupled receptor kinase-interacting protein 1 C term TRP PF06011.12 OIR58591.1 - 0.0016 17.3 0.2 0.0018 17.1 0.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DASH_Duo1 PF08651.10 OIR58591.1 - 0.012 15.4 5.4 2.4 8.0 0.3 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 SNARE PF05739.19 OIR58591.1 - 0.015 15.3 1.0 0.015 15.3 1.0 3.1 2 1 1 3 3 3 0 SNARE domain Laminin_II PF06009.12 OIR58591.1 - 0.016 15.2 3.9 0.22 11.5 0.5 2.3 2 0 0 2 2 2 0 Laminin Domain II PL48 PF15903.5 OIR58591.1 - 0.02 13.9 1.3 0.025 13.5 1.3 1.2 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 EMP24_GP25L PF01105.24 OIR58591.1 - 0.024 14.6 4.9 0.067 13.1 1.2 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2031 PF09592.10 OIR58591.1 - 0.028 13.9 9.5 0.19 11.2 9.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) WXG100 PF06013.12 OIR58591.1 - 0.12 12.7 2.5 3.8 7.8 0.1 2.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG PKHD_C PF18331.1 OIR58591.1 - 0.12 12.5 0.3 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain RecG_N PF17190.4 OIR58591.1 - 0.15 12.9 1.7 3.7 8.3 0.1 3.0 2 1 0 3 3 3 0 RecG N-terminal helical domain SbsC_C PF18058.1 OIR58591.1 - 0.16 12.2 6.0 2 8.7 1.2 2.4 2 1 0 2 2 2 0 SbsC C-terminal domain CENP-F_leu_zip PF10473.9 OIR58591.1 - 0.25 11.4 5.2 0.19 11.7 0.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rx_N PF18052.1 OIR58591.1 - 0.54 10.6 2.5 20 5.5 0.3 2.7 2 1 1 3 3 3 0 Rx N-terminal domain DUF1664 PF07889.12 OIR58591.1 - 1 9.4 8.8 3.7 7.6 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 OIR58591.1 - 1.1 9.8 6.0 14 6.1 0.3 2.4 2 0 0 2 2 2 0 Snapin/Pallidin Syntaxin-6_N PF09177.11 OIR58591.1 - 1.4 9.5 7.8 7.6 7.2 0.9 2.9 2 2 1 3 3 3 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 OIR58591.1 - 9.3 6.7 8.9 34 4.9 0.6 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Nse4_C PF08743.10 OIR58592.1 - 1.6e-16 60.3 0.3 1.6e-16 60.3 0.3 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Tubulin PF00091.25 OIR58593.1 - 1.4e-67 227.7 0.0 1.9e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OIR58593.1 - 5.3e-47 159.1 0.0 8.6e-47 158.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OIR58593.1 - 0.0026 17.5 0.0 0.0084 15.8 0.0 1.9 2 1 0 2 2 2 1 Tubulin domain TPT PF03151.16 OIR58594.1 - 4.5e-23 82.0 13.3 5.4e-23 81.8 13.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OIR58594.1 - 1.4e-05 25.3 27.9 0.0043 17.2 11.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family NOT2_3_5 PF04153.18 OIR58595.1 - 1.6e-31 109.1 11.7 2.1e-31 108.7 11.7 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family YgaB PF14182.6 OIR58595.1 - 0.058 13.8 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 YgaB-like protein Ribosomal_S8 PF00410.19 OIR58596.1 - 3e-17 62.7 0.0 5.2e-17 62.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Nucleoside_tran PF01733.18 OIR58597.1 - 2.2e-15 56.9 19.3 5e-15 55.7 17.8 2.1 1 1 0 1 1 1 1 Nucleoside transporter DUF443 PF04276.12 OIR58597.1 - 0.00075 19.4 0.5 0.00075 19.4 0.5 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF443) DUF5316 PF17247.2 OIR58597.1 - 2 8.5 5.6 0.96 9.5 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5316) ECR1_N PF14382.6 OIR58598.1 - 5.9e-09 35.6 0.2 1.6e-08 34.2 0.2 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region TPR_2 PF07719.17 OIR58599.1 - 9.1e-14 50.4 6.4 0.15 12.3 0.2 8.0 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 OIR58599.1 - 1.1e-11 44.0 1.8 0.016 15.0 0.3 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OIR58599.1 - 1.7e-11 43.4 0.3 0.004 17.3 0.1 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OIR58599.1 - 1.2e-09 38.2 0.1 0.16 12.9 0.0 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR58599.1 - 7.2e-08 32.9 0.0 0.034 14.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OIR58599.1 - 2.4e-06 27.2 0.1 0.071 13.2 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OIR58599.1 - 2.4e-06 27.9 0.0 1.3 9.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OIR58599.1 - 1.2e-05 24.7 0.0 0.039 13.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 OIR58599.1 - 2.2e-05 24.8 2.1 2.2 9.1 0.1 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR58599.1 - 2.7e-05 24.4 0.3 0.48 10.7 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 OIR58599.1 - 0.00012 21.7 0.0 0.89 9.3 0.0 4.2 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 OIR58599.1 - 0.036 14.3 0.0 9 6.6 0.0 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 OIR58599.1 - 0.047 14.1 0.0 2.4 8.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 OIR58599.1 - 0.048 14.0 0.0 2.5 8.5 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SPT6_acidic PF14632.6 OIR58599.1 - 0.19 12.3 8.4 0.54 10.9 8.4 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PHD PF00628.29 OIR58600.1 - 2.7e-06 27.1 9.0 2.7e-06 27.1 9.0 2.5 2 1 0 2 2 2 1 PHD-finger PA26 PF04636.13 OIR58600.1 - 0.11 11.3 1.4 0.23 10.4 1.4 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MCPsignal PF00015.21 OIR58600.1 - 0.24 11.2 1.1 0.4 10.5 1.1 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Ndc1_Nup PF09531.10 OIR58600.1 - 0.26 9.9 4.1 0.76 8.4 3.9 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup BSP_II PF05432.11 OIR58600.1 - 1.2 8.7 15.7 0.038 13.7 9.5 1.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Presenilin PF01080.17 OIR58600.1 - 5.4 5.7 11.0 0.14 10.9 4.7 1.5 2 0 0 2 2 2 0 Presenilin Nup54 PF13874.6 OIR58601.1 - 0.0016 18.6 0.1 0.0019 18.3 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 DUF5344 PF17279.2 OIR58601.1 - 0.038 14.6 0.1 0.048 14.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5344) DUF3086 PF11285.8 OIR58601.1 - 0.47 9.5 5.2 7.3 5.6 2.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3086) WH2 PF02205.20 OIR58602.1 - 6e-05 22.7 1.3 8.1e-05 22.3 0.2 1.8 2 0 0 2 2 2 1 WH2 motif SPX PF03105.19 OIR58602.1 - 0.02 14.8 13.8 0.027 14.4 13.8 1.2 1 0 0 1 1 1 0 SPX domain WD40 PF00400.32 OIR58603.1 - 1.3e-10 41.7 12.4 0.042 14.7 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CDC45 PF02724.14 OIR58604.1 - 7.1e-66 222.8 13.7 5.8e-43 147.1 8.5 3.0 1 1 1 2 2 2 2 CDC45-like protein CDT1 PF08839.11 OIR58605.1 - 2e-12 47.8 2.6 2e-11 44.5 1.4 2.3 1 1 1 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 OIR58605.1 - 1.5e-11 44.5 3.6 9.5e-11 42.0 3.2 2.4 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain PRD PF00874.20 OIR58605.1 - 0.073 13.4 0.9 9 6.7 0.5 2.5 2 0 0 2 2 2 0 PRD domain G6PD_N PF00479.22 OIR58606.1 - 4.2e-44 151.3 0.0 6.5e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 OIR58606.1 - 5e-17 62.0 0.0 5e-09 35.8 0.0 3.0 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain Vps16_N PF04841.13 OIR58607.1 - 0.0052 15.6 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region CotE PF10628.9 OIR58607.1 - 0.017 14.8 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) RSN1_7TM PF02714.15 OIR58608.1 - 3.8e-19 69.1 20.9 3.8e-19 69.1 20.9 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OIR58608.1 - 2.7e-06 27.7 0.0 0.0013 19.0 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OIR58608.1 - 0.0024 17.6 1.0 0.0024 17.6 1.0 3.9 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport RNA_bind PF08675.11 OIR58608.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain HHV-5_US34A PF17087.5 OIR58609.1 - 0.018 15.2 0.8 0.059 13.5 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus US34A protein family Arf PF00025.21 OIR58610.1 - 1.5e-77 259.0 0.3 1.7e-77 258.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OIR58610.1 - 4.4e-14 52.7 0.1 6.2e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OIR58610.1 - 1.4e-13 50.7 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OIR58610.1 - 1.1e-12 47.9 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OIR58610.1 - 1.5e-12 47.3 0.8 1.8e-08 33.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 OIR58610.1 - 3.1e-09 36.6 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OIR58610.1 - 3.8e-05 23.8 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OIR58610.1 - 0.0029 16.9 0.2 0.0078 15.5 0.1 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase mRNA_cap_enzyme PF01331.19 OIR58611.1 - 1.5e-33 116.3 0.0 2.5e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OIR58611.1 - 1.8e-20 73.6 0.1 2.9e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OIR58611.1 - 3.8e-05 23.4 0.0 0.0017 18.0 0.0 2.3 1 1 1 2 2 2 1 ATP dependent DNA ligase domain TolA_bind_tri PF16331.5 OIR58612.1 - 0.0094 16.0 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 TolA binding protein trimerisation BAH PF01426.18 OIR58612.1 - 0.052 13.4 0.2 0.089 12.7 0.2 1.4 1 0 0 1 1 1 0 BAH domain TMPIT PF07851.13 OIR58612.1 - 0.089 12.0 1.0 0.11 11.8 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ycf66_N PF07444.11 OIR58612.1 - 0.12 12.5 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Ycf66 protein N-terminus Fez1 PF06818.15 OIR58612.1 - 0.35 11.3 5.3 0.45 10.9 5.3 1.1 1 0 0 1 1 1 0 Fez1 E2F_TDP PF02319.20 OIR58613.1 - 6.4e-07 29.3 0.4 1.8e-06 27.9 0.0 1.8 2 1 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 OIR58613.1 - 0.065 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RuvB_C PF05491.13 OIR58613.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain HTH_24 PF13412.6 OIR58613.1 - 0.069 12.7 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 OIR58613.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 OIR58613.1 - 0.14 12.5 0.2 0.54 10.6 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator CRAL_TRIO PF00650.20 OIR58614.1 - 8.6e-23 80.8 0.1 1.6e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OIR58614.1 - 0.00013 22.1 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HetR_C PF18460.1 OIR58614.1 - 0.29 11.1 1.1 8 6.5 0.0 2.8 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Mt_ATP-synt_B PF05405.14 OIR58614.1 - 0.94 9.1 5.0 0.34 10.5 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Allexi_40kDa PF05549.11 OIR58615.1 - 0.024 14.2 0.2 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein KxDL PF10241.9 OIR58615.1 - 0.029 14.6 1.7 0.26 11.6 1.7 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein HlyD_2 PF12700.7 OIR58615.1 - 0.079 11.7 1.1 0.13 11.0 1.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Trypan_PARP PF05887.11 OIR58615.1 - 0.27 11.2 12.5 0.67 9.9 12.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) XhlA PF10779.9 OIR58615.1 - 0.42 10.9 3.9 0.89 9.8 3.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA LRR_8 PF13855.6 OIR58616.1 - 1e-33 114.9 55.9 5.9e-09 35.6 1.7 7.9 6 2 3 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 OIR58616.1 - 2.7e-21 75.3 59.7 9.7e-05 22.7 3.8 11.5 5 3 4 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OIR58616.1 - 8.2e-19 67.9 0.0 1.7e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PP2C PF00481.21 OIR58616.1 - 1.2e-16 61.2 0.0 2.4e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 OIR58616.1 - 4.5e-06 26.3 20.1 0.038 13.5 0.6 4.5 3 1 1 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 OIR58616.1 - 5.3 7.0 7.4 13 5.8 1.2 3.1 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) PMI_typeI PF01238.21 OIR58617.1 - 2.6e-68 230.9 0.3 2.2e-66 224.6 0.3 2.6 1 1 0 1 1 1 1 Phosphomannose isomerase type I PqqD PF05402.12 OIR58617.1 - 0.04 14.2 0.0 0.71 10.2 0.0 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Mpp10 PF04006.12 OIR58620.1 - 2.3e-27 95.7 12.4 5.9e-23 81.2 12.4 2.1 2 0 0 2 2 2 2 Mpp10 protein Ntox16 PF15523.6 OIR58622.1 - 0.16 12.2 3.4 0.13 12.5 0.8 2.1 2 1 0 2 2 2 0 Novel toxin 16 Nrap_D4 PF17405.2 OIR58623.1 - 5.9e-13 48.7 0.1 2.8e-12 46.4 0.1 1.9 1 1 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Snf7 PF03357.21 OIR58624.1 - 6.8e-31 107.2 22.0 6.8e-31 107.2 22.0 1.4 1 1 1 2 2 2 1 Snf7 DUF3298 PF11738.8 OIR58624.1 - 0.54 11.3 4.6 0.84 10.7 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3298) CDRT4 PF15213.6 OIR58624.1 - 0.77 10.4 4.6 0.13 12.9 0.6 1.7 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein CDC73_N PF16050.5 OIR58625.1 - 1.7e-09 37.5 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal DUF1036 PF06282.11 OIR58625.1 - 0.041 14.4 1.1 0.076 13.6 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1036) ABC_tran PF00005.27 OIR58626.1 - 2.3e-44 151.2 7.5 3.3e-22 79.5 0.1 3.4 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 OIR58626.1 - 2.2e-24 85.3 1.0 2.2e-24 85.3 1.0 2.6 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 OIR58626.1 - 1.3e-12 47.7 3.0 2.2e-05 24.0 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OIR58626.1 - 1.4e-10 41.5 17.7 0.035 13.9 0.3 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OIR58626.1 - 2.4e-07 30.8 0.3 0.0063 16.4 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 OIR58626.1 - 6.9e-07 29.6 0.4 0.0079 16.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 OIR58626.1 - 1.3e-06 28.5 0.1 0.0049 16.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OIR58626.1 - 2.2e-06 28.2 0.5 0.065 13.6 0.2 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OIR58626.1 - 5e-06 26.2 0.2 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 OIR58626.1 - 1.4e-05 25.1 0.0 0.075 13.0 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 OIR58626.1 - 1.9e-05 24.7 0.4 1.3 9.0 0.0 4.0 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OIR58626.1 - 2e-05 25.2 0.3 0.08 13.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OIR58626.1 - 5.1e-05 23.1 1.6 0.25 11.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 OIR58626.1 - 6e-05 23.5 0.4 0.7 10.3 0.0 3.6 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OIR58626.1 - 7.2e-05 22.8 3.0 0.33 10.8 0.0 3.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OIR58626.1 - 0.00013 22.3 0.0 0.41 11.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 OIR58626.1 - 0.00035 20.8 0.1 1.6 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OIR58626.1 - 0.00077 19.2 0.3 0.37 10.5 0.2 3.3 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OIR58626.1 - 0.00085 19.3 0.0 0.65 9.9 0.0 2.8 3 0 0 3 3 2 1 NTPase AAA_14 PF13173.6 OIR58626.1 - 0.0011 19.0 1.6 1.6 8.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_7 PF12775.7 OIR58626.1 - 0.0018 17.8 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Septin PF00735.18 OIR58626.1 - 0.0027 17.1 0.1 1 8.6 0.0 2.6 2 0 0 2 2 2 1 Septin IstB_IS21 PF01695.17 OIR58626.1 - 0.0083 15.9 0.0 3.2 7.5 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein Roc PF08477.13 OIR58626.1 - 0.011 16.0 0.1 7.3 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 OIR58626.1 - 0.014 14.6 1.9 1 8.5 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain AAA_28 PF13521.6 OIR58626.1 - 0.017 15.4 2.7 14 5.9 0.0 4.0 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 OIR58626.1 - 0.017 14.1 0.6 1.3 7.9 0.0 2.7 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 OIR58626.1 - 0.02 14.7 19.5 0.23 11.1 0.0 4.7 3 1 1 4 4 4 0 AAA ATPase domain dNK PF01712.19 OIR58626.1 - 0.02 14.8 0.9 7.1 6.4 0.0 3.3 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_23 PF13476.6 OIR58626.1 - 0.029 14.9 0.0 0.029 14.9 0.0 4.4 5 0 0 5 5 4 0 AAA domain TsaE PF02367.17 OIR58626.1 - 0.05 13.6 0.3 12 5.9 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 OIR58626.1 - 0.053 13.1 0.3 4.6 6.8 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NARP1 PF12569.8 OIR58626.1 - 0.082 11.8 7.5 0.14 11.0 7.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_A32 PF04665.12 OIR58626.1 - 0.083 12.3 1.5 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Poxvirus A32 protein DUF87 PF01935.17 OIR58626.1 - 0.14 12.2 8.6 6 6.9 0.0 3.9 4 0 0 4 4 3 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 OIR58626.1 - 0.2 11.3 0.2 8.4 6.0 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CCDC106 PF15794.5 OIR58626.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.5 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 106 AAA_17 PF13207.6 OIR58626.1 - 0.33 11.4 4.0 30 5.0 0.0 3.8 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 OIR58626.1 - 0.47 10.2 2.3 2.7 7.7 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 OIR58626.1 - 0.58 9.8 3.0 2.6 7.6 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 OIR58626.1 - 1.4 8.6 9.8 11 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Med6 PF04934.14 OIR58627.1 - 3.7e-33 114.1 0.0 4.4e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF2989 PF11207.8 OIR58627.1 - 0.08 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) RGS PF00615.19 OIR58628.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 Regulator of G protein signaling domain Ribosomal_L7Ae PF01248.26 OIR58629.1 - 4.3e-19 68.0 0.5 8.1e-19 67.2 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Thx PF17070.5 OIR58629.1 - 0.046 13.8 1.7 0.046 13.8 1.7 3.1 4 0 0 4 4 4 0 30S ribosomal protein Thx Brix PF04427.18 OIR58630.1 - 4.8e-21 75.8 0.0 5.5e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Brix domain GATase1_like PF07090.11 OIR58630.1 - 0.025 14.0 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative glutamine amidotransferase Erf4 PF10256.9 OIR58631.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_2 PF07719.17 OIR58633.1 - 8.4e-23 78.6 15.6 8.6e-05 22.4 0.1 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 OIR58633.1 - 2.5e-16 58.7 15.6 6.5e-05 22.6 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 OIR58633.1 - 1.8e-14 53.8 10.8 1.8e-06 28.1 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 OIR58633.1 - 9.4e-11 41.6 4.2 0.61 11.1 0.0 7.4 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OIR58633.1 - 5e-10 38.8 6.1 0.88 10.0 0.1 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 OIR58633.1 - 4e-09 36.0 8.2 6.8e-05 22.5 0.0 6.2 6 1 1 7 7 6 2 TPR repeat TPR_16 PF13432.6 OIR58633.1 - 1.1e-08 35.5 4.8 0.0055 17.3 0.2 5.3 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OIR58633.1 - 2.1e-08 33.6 6.2 0.00038 20.3 0.4 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR58633.1 - 1e-07 32.1 8.2 0.028 14.6 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OIR58633.1 - 1.2e-06 28.6 0.7 0.0047 17.0 0.0 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 OIR58633.1 - 2.8e-05 23.9 1.9 0.00025 20.8 0.2 3.5 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 OIR58633.1 - 3.4e-05 23.9 0.4 0.6 10.6 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 OIR58633.1 - 0.00036 20.3 9.3 0.03 14.2 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat SNAP PF14938.6 OIR58633.1 - 0.0059 16.1 2.8 0.023 14.1 0.5 2.7 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 OIR58633.1 - 0.0076 15.7 0.6 0.97 8.7 0.0 2.9 1 1 1 3 3 3 1 MalT-like TPR region TPR_19 PF14559.6 OIR58633.1 - 0.0099 16.4 1.7 64 4.2 0.0 5.0 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 OIR58633.1 - 0.011 16.3 0.4 0.86 10.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OIR58633.1 - 0.015 15.3 4.2 2.8 8.1 0.2 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.15 OIR58633.1 - 0.052 13.7 0.6 22 5.1 0.0 3.6 2 1 2 4 4 4 0 MAS20 protein import receptor SRP_TPR_like PF17004.5 OIR58633.1 - 0.11 12.5 0.0 2.1 8.4 0.0 3.0 3 1 0 3 3 2 0 Putative TPR-like repeat PknG_TPR PF16918.5 OIR58633.1 - 0.12 11.1 0.0 4.7 5.8 0.0 2.3 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat Paf67 PF10255.9 OIR58633.1 - 0.16 10.9 0.1 0.91 8.4 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 VHS PF00790.19 OIR58634.1 - 0.0042 16.9 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 VHS domain Pkinase PF00069.25 OIR58635.1 - 1.7e-39 135.8 0.0 4.3e-39 134.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58635.1 - 1.2e-19 70.6 0.0 3.8e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR58635.1 - 0.00065 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR58635.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OIR58635.1 - 0.021 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TruD PF01142.18 OIR58637.1 - 2e-54 185.0 1.8 1.6e-35 122.7 0.5 4.6 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) zf-ZPR1 PF03367.13 OIR58638.1 - 3.6e-86 286.9 1.3 1.2e-44 151.9 0.0 2.0 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 OIR58638.1 - 0.037 14.1 2.5 5.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DnaJ_CXXCXGXG PF00684.19 OIR58638.1 - 0.12 12.8 7.3 0.089 13.2 1.1 2.7 2 0 0 2 2 2 0 DnaJ central domain OrfB_Zn_ribbon PF07282.11 OIR58638.1 - 0.19 11.7 5.2 0.54 10.2 0.0 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Proteasome PF00227.26 OIR58640.1 - 5.7e-30 104.2 0.0 8.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit RasGEF PF00617.19 OIR58642.1 - 1.9e-34 119.4 1.9 3.7e-34 118.5 1.9 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OIR58642.1 - 4e-05 23.8 2.0 4e-05 23.8 2.0 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif DNA_RNApol_7kD PF03604.13 OIR58643.1 - 4.5e-16 58.2 6.0 5.7e-16 57.9 6.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit PhnA_Zn_Ribbon PF08274.12 OIR58643.1 - 0.0016 18.4 0.2 0.0034 17.3 0.3 1.5 1 1 1 2 2 2 1 PhnA Zinc-Ribbon OrfB_Zn_ribbon PF07282.11 OIR58643.1 - 0.0038 17.1 0.2 0.0048 16.8 0.2 1.1 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DZR PF12773.7 OIR58643.1 - 0.0084 16.1 0.3 0.01 15.9 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 OIR58643.1 - 0.018 15.1 0.4 6.4 6.9 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Tnp_zf-ribbon_2 PF13842.6 OIR58643.1 - 0.019 15.7 2.8 1.9 9.4 1.5 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon HypA PF01155.19 OIR58643.1 - 0.02 14.9 0.4 0.021 14.8 0.4 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_13 PF09855.9 OIR58643.1 - 0.021 15.0 0.1 0.021 15.0 0.1 1.8 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) A2L_zn_ribbon PF08792.10 OIR58643.1 - 0.021 14.5 3.1 0.028 14.1 3.1 1.2 1 0 0 1 1 1 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.12 OIR58643.1 - 0.028 14.0 2.0 1 8.9 0.7 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 OIR58643.1 - 0.03 14.5 2.2 0.066 13.3 2.2 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Lar_restr_allev PF14354.6 OIR58643.1 - 0.031 14.7 2.4 2.7 8.4 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.6 OIR58643.1 - 0.039 14.5 3.0 0.47 11.0 0.1 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-RING_7 PF02591.15 OIR58643.1 - 0.045 13.9 3.7 0.14 12.4 3.7 1.8 1 1 0 1 1 1 0 C4-type zinc ribbon domain Rubredoxin_2 PF18073.1 OIR58643.1 - 0.052 13.3 5.1 0.68 9.7 0.8 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 OIR58643.1 - 0.079 12.7 3.9 0.75 9.6 3.6 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Vps36-NZF-N PF16988.5 OIR58643.1 - 0.081 12.3 0.8 0.19 11.1 0.8 1.7 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-ribbon_3 PF13248.6 OIR58643.1 - 0.082 12.3 2.7 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 OIR58643.1 - 0.13 11.9 1.2 2.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger BRCT PF00533.26 OIR58644.1 - 0.007 16.7 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OIR58644.1 - 0.085 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HSCB_C PF07743.13 OIR58645.1 - 0.00016 22.1 0.1 0.00026 21.4 0.1 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OIR58645.1 - 0.00019 21.5 0.0 0.00046 20.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TFIIF_alpha PF05793.12 OIR58646.1 - 5.6e-09 35.1 0.3 5.6e-09 35.1 0.3 2.3 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SPT16 PF08644.11 OIR58647.1 - 3.2e-36 124.8 0.2 3.2e-36 124.8 0.2 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 OIR58647.1 - 1.6e-14 54.1 0.0 5.4e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Mg_chelatase_C PF13335.6 OIR58647.1 - 0.049 14.3 0.2 0.16 12.6 0.2 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal NapB PF03892.14 OIR58647.1 - 0.21 11.6 5.3 0.048 13.7 1.5 1.9 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) UCH PF00443.29 OIR58648.1 - 2e-46 158.6 0.0 2.6e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OIR58648.1 - 6.1e-14 52.3 0.0 1.1e-11 44.9 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OIR58648.1 - 1.7e-13 50.7 9.4 1.7e-13 50.7 9.4 2.6 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 OIR58648.1 - 0.12 12.1 2.2 1 9.2 0.8 3.0 3 0 0 3 3 3 0 Variant UBP zinc finger Polysacc_deac_1 PF01522.21 OIR58651.1 - 4e-30 104.3 0.0 7.2e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase rRNA_methylase PF06962.12 OIR58651.1 - 0.13 12.2 0.0 0.96 9.4 0.0 2.0 2 0 0 2 2 2 0 Putative rRNA methylase Pkinase PF00069.25 OIR58652.1 - 4.3e-49 167.3 0.0 6.3e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58652.1 - 2.9e-22 79.2 0.0 4.5e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OIR58652.1 - 0.012 15.0 1.5 0.014 14.8 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OIR58652.1 - 0.044 13.4 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OIR58652.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 OIR58653.1 - 4.6e-51 169.7 32.2 1.4e-08 35.3 0.2 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58653.1 - 2.6e-15 56.5 0.8 7.7e-05 22.9 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OIR58653.1 - 1.3e-06 27.6 0.0 0.0034 16.4 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OIR58653.1 - 2.1e-05 24.5 0.1 0.021 14.7 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OIR58653.1 - 0.0069 16.3 0.4 31 4.7 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 OIR58653.1 - 0.057 13.1 0.1 15 5.4 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature DUF5122 PF17164.4 OIR58653.1 - 0.12 12.7 0.1 2.7 8.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller tRNA-synt_His PF13393.6 OIR58654.1 - 3.5e-46 157.9 0.0 4.2e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OIR58654.1 - 6.7e-09 35.8 1.4 1.2e-07 31.7 0.5 2.6 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 OIR58654.1 - 0.00043 19.5 0.5 0.026 13.6 0.1 2.9 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 OIR58654.1 - 0.00051 19.6 0.1 0.0035 16.9 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class II core domain (F) NTP_transf_3 PF12804.7 OIR58654.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain MOZ_SAS PF01853.18 OIR58655.1 - 2.8e-63 212.8 0.0 4.5e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OIR58655.1 - 3.7e-06 26.4 0.1 3.7e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 OIR58655.1 - 0.039 14.4 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HNF-1_N PF04814.13 OIR58655.1 - 0.087 13.4 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus MarR_2 PF12802.7 OIR58655.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.6 1 1 0 1 1 1 0 MarR family Polysacc_deac_1 PF01522.21 OIR58656.1 - 1e-34 119.1 0.0 1.8e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OIR58656.1 - 4.5e-05 22.8 0.4 0.00016 21.0 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OIR58656.1 - 0.0075 15.9 0.5 0.03 14.0 0.4 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) G6B PF15096.6 OIR58656.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 G6B family Peptidase_M16_M PF16187.5 OIR58657.1 - 2.7e-31 108.9 0.0 4.2e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OIR58657.1 - 2.2e-30 105.6 0.5 4.1e-28 98.2 0.0 3.0 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OIR58657.1 - 6e-30 104.6 0.0 9.6e-22 77.9 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain AAA PF00004.29 OIR58658.1 - 0.16 12.4 0.8 0.57 10.6 0.8 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRM PF02005.16 OIR58659.1 - 3.8e-114 381.8 0.0 4.4e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 OIR58659.1 - 1.2e-08 35.0 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 OIR58659.1 - 0.0098 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OIR58659.1 - 0.02 15.6 0.0 0.57 10.9 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain HEAT PF02985.22 OIR58660.1 - 2.2e-08 33.6 2.2 0.006 16.7 0.0 6.5 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 OIR58660.1 - 3.5e-07 30.6 1.8 0.0011 19.4 0.0 5.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 OIR58660.1 - 1.7e-05 25.1 0.2 0.51 10.8 0.2 4.3 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 OIR58660.1 - 0.0016 18.5 0.0 6.5 6.8 0.0 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OIR58660.1 - 0.0025 17.4 0.0 0.18 11.3 0.0 3.0 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 OIR58660.1 - 0.09 13.4 0.0 4.3 8.0 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ribosomal_S6e PF01092.19 OIR58661.1 - 1.1e-47 161.1 1.7 2.5e-47 160.0 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S6e DHHC PF01529.20 OIR58662.1 - 6.2e-29 100.8 7.9 6.2e-29 100.8 7.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Vut_1 PF02592.15 OIR58662.1 - 0.0051 17.2 7.7 0.081 13.2 0.8 2.3 2 0 0 2 2 2 2 Putative vitamin uptake transporter DUF3995 PF13160.6 OIR58662.1 - 0.016 15.5 1.6 0.016 15.5 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) 7tm_7 PF08395.12 OIR58662.1 - 0.059 12.6 8.3 0.018 14.3 2.2 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF2207 PF09972.9 OIR58662.1 - 0.085 11.6 2.1 0.19 10.4 0.6 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Chromate_transp PF02417.15 OIR58662.1 - 0.1 12.7 5.3 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Chromate transporter Phage_holin_3_6 PF07332.11 OIR58662.1 - 0.42 10.7 14.5 0.52 10.4 8.3 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3810 PF12725.7 OIR58662.1 - 1 8.6 3.7 7.1 5.9 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) AtpR PF12966.7 OIR58662.1 - 1.7 9.2 8.8 0.28 11.7 3.9 2.1 2 1 0 2 2 2 0 N-ATPase, AtpR subunit DUF485 PF04341.12 OIR58662.1 - 2.5 8.1 9.7 3.4 7.7 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Bromodomain PF00439.25 OIR58663.1 - 1.4e-24 85.9 0.6 2.6e-24 85.1 0.6 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 OIR58663.1 - 7.3e-10 38.9 0.1 1.8e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OIR58663.1 - 1e-09 38.6 0.0 1.8e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OIR58663.1 - 5e-08 33.2 0.5 1.1e-07 32.2 0.5 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OIR58663.1 - 0.00054 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 OIR58663.1 - 0.021 15.5 0.1 0.23 12.1 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Fur_reg_FbpB PF13040.6 OIR58663.1 - 0.026 14.1 1.8 0.054 13.1 1.8 1.5 1 0 0 1 1 1 0 Fur-regulated basic protein B Acetyltransf_4 PF13420.7 OIR58663.1 - 0.072 13.2 0.4 0.23 11.6 0.2 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FANCL_C PF11793.8 OIR58665.1 - 0.00089 19.4 2.7 0.0017 18.5 2.7 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 OIR58665.1 - 0.0035 17.7 4.8 0.0069 16.7 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 OIR58665.1 - 0.0056 16.9 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OIR58665.1 - 0.072 13.3 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 OIR58665.1 - 0.19 12.1 5.3 0.38 11.1 5.3 1.6 1 0 0 1 1 1 0 RING-like domain Utp21 PF04192.12 OIR58666.1 - 1.9e-09 37.4 0.5 3.7e-09 36.4 0.5 1.5 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40_like PF17005.5 OIR58666.1 - 4.4e-05 23.0 4.0 0.2 11.0 0.3 3.1 2 1 1 3 3 3 2 WD40-like domain Coatomer_WDAD PF04053.14 OIR58666.1 - 0.00023 20.3 0.8 0.00071 18.7 0.4 1.9 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 OIR58666.1 - 0.00024 21.3 0.6 1.4 9.3 0.0 4.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 OIR58666.1 - 0.00051 19.5 0.5 0.0023 17.3 0.2 2.3 2 0 0 2 2 2 1 CPSF A subunit region HPS3_N PF14761.6 OIR58666.1 - 0.0013 18.3 5.2 0.84 9.1 0.1 3.9 4 1 1 5 5 5 2 Hermansky-Pudlak syndrome 3 Cytochrom_D1 PF02239.16 OIR58666.1 - 0.0048 15.5 0.0 0.074 11.6 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40 PF00400.32 OIR58666.1 - 0.0083 17.0 7.1 0.82 10.7 0.0 5.9 6 0 0 6 6 6 1 WD domain, G-beta repeat PQQ_2 PF13360.6 OIR58666.1 - 0.012 15.2 0.1 0.23 11.0 0.1 3.0 2 1 1 3 3 3 0 PQQ-like domain CLTH PF10607.9 OIR58668.1 - 7e-18 64.9 0.4 1e-17 64.4 0.4 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PPI_Ypi1 PF07491.11 OIR58669.1 - 4.3e-18 64.9 3.8 4.6e-18 64.8 3.8 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor SCAMP PF04144.13 OIR58670.1 - 1.2e-10 42.0 11.6 1.5e-10 41.7 11.6 1.1 1 0 0 1 1 1 1 SCAMP family TCTP PF00838.17 OIR58671.1 - 1.8e-56 191.0 0.3 2e-56 190.9 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein NIF PF03031.18 OIR58672.1 - 7.5e-25 87.5 0.0 1.3e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acetyltransf_1 PF00583.25 OIR58673.1 - 2.4e-12 47.1 0.0 2.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OIR58673.1 - 1.6e-10 41.0 0.0 2.2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR58673.1 - 3.3e-07 30.6 0.1 4.8e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OIR58673.1 - 4.2e-05 24.3 0.0 5.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OIR58673.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OIR58673.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TRAP_beta PF05753.14 OIR58673.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.3 1 1 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Acetyltransf_6 PF13480.7 OIR58673.1 - 0.19 11.9 0.0 0.34 11.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ebp2 PF05890.12 OIR58674.1 - 0.003 17.2 42.5 0.004 16.8 42.5 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 PseudoU_synth_1 PF01416.20 OIR58675.1 - 1.6e-14 54.3 0.0 3.8e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase Trm112p PF03966.16 OIR58676.1 - 5.6e-10 39.7 0.1 6.9e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-CHY PF05495.12 OIR58677.1 - 4e-11 43.2 5.8 4e-11 43.2 5.8 3.3 2 1 1 3 3 3 1 CHY zinc finger RE_Alw26IDE PF09665.10 OIR58677.1 - 0.09 11.9 0.2 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) zinc_ribbon_4 PF13717.6 OIR58677.1 - 2.4 8.1 12.8 11 6.0 0.2 4.8 5 0 0 5 5 5 0 zinc-ribbon domain HypA PF01155.19 OIR58677.1 - 8.3 6.5 20.2 0.36 10.9 0.2 4.0 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Dus PF01207.17 OIR58678.1 - 6.5e-74 248.8 0.0 8e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 OIR58678.1 - 1.1e-07 31.5 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 OIR58678.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 OIR58678.1 - 1.5e-05 24.5 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase SOR_SNZ PF01680.17 OIR58678.1 - 2.2e-05 24.4 0.3 0.00014 21.7 0.0 2.0 1 1 1 2 2 2 1 SOR/SNZ family DHO_dh PF01180.21 OIR58678.1 - 0.0033 16.7 0.0 0.16 11.1 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 OIR58678.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase Regnase_1_C PF18561.1 OIR58678.1 - 0.094 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain G3P_antiterm PF04309.12 OIR58678.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator NanE PF04131.14 OIR58678.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 OIR58678.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain PI31_Prot_C PF08577.11 OIR58679.1 - 1e-05 26.6 1.0 1.1e-05 26.5 0.1 1.5 2 0 0 2 2 2 1 PI31 proteasome regulator zf-Nse PF11789.8 OIR58680.1 - 2.3e-15 56.1 0.1 4.3e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 OIR58680.1 - 0.00028 20.8 0.2 0.00066 19.6 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OIR58680.1 - 0.00043 20.1 0.1 0.00099 18.9 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 OIR58680.1 - 0.0039 16.9 0.7 0.012 15.3 0.5 1.9 1 1 1 2 2 2 1 MIZ/SP-RING zinc finger zf-RING_2 PF13639.6 OIR58680.1 - 0.0076 16.6 0.2 0.021 15.2 0.2 1.8 1 1 0 1 1 1 1 Ring finger domain DUF3617 PF12276.8 OIR58680.1 - 0.02 15.2 0.8 0.057 13.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) zf-rbx1 PF12678.7 OIR58680.1 - 0.021 15.1 0.3 0.062 13.6 0.0 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 OIR58680.1 - 0.053 13.1 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 OIR58680.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MAP65_ASE1 PF03999.12 OIR58681.1 - 1.2e-07 30.8 36.9 8.3e-06 24.8 37.0 2.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) P30 PF07390.11 OIR58681.1 - 0.054 13.6 1.8 0.25 11.4 0.2 2.5 2 0 0 2 2 2 0 Mycoplasma P30 protein IPT PF01745.16 OIR58681.1 - 0.17 11.2 3.4 0.34 10.3 0.1 2.6 2 1 0 2 2 2 0 Isopentenyl transferase T_Ag_DNA_bind PF02217.16 OIR58681.1 - 0.2 12.3 1.2 35 5.1 0.2 3.4 2 1 2 4 4 4 0 Origin of replication binding protein eIF-5a PF01287.20 OIR58682.1 - 1.5e-24 85.9 0.2 2.2e-24 85.3 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OIR58682.1 - 4.3e-05 23.5 0.1 6.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain DHQS PF01959.16 OIR58682.1 - 0.085 11.7 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase II TFIIA_gamma_C PF02751.14 OIR58683.1 - 9.7e-20 70.5 1.6 1.5e-19 69.8 1.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 OIR58683.1 - 2.3e-18 65.9 0.2 3.9e-18 65.2 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain SH3_1 PF00018.28 OIR58684.1 - 1.4e-07 31.0 0.4 0.00038 20.0 0.0 3.1 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OIR58684.1 - 7.9e-07 28.8 0.4 0.048 13.5 0.0 2.9 2 1 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OIR58684.1 - 4.2e-05 23.2 0.0 0.041 13.6 0.0 2.5 2 1 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 OIR58684.1 - 0.002 18.4 0.0 0.074 13.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain Proteasome PF00227.26 OIR58685.1 - 1.5e-45 155.0 0.0 2.2e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR58685.1 - 2.6e-11 43.0 0.1 5.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature His_Phos_2 PF00328.22 OIR58686.1 - 1.9e-15 57.1 0.0 4.2e-11 42.8 0.0 2.8 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Yos1 PF08571.10 OIR58687.1 - 3.2e-16 59.3 5.8 4.5e-16 58.9 5.8 1.2 1 0 0 1 1 1 1 Yos1-like AMP-binding PF00501.28 OIR58688.1 - 0.091 11.3 0.7 0.13 10.8 0.2 1.4 1 1 1 2 2 2 0 AMP-binding enzyme DUF3974 PF13120.6 OIR58688.1 - 0.095 12.8 1.9 0.2 11.8 1.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3974) Fis1_TPR_C PF14853.6 OIR58689.1 - 0.00036 20.6 1.3 0.00036 20.6 1.3 1.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 OIR58689.1 - 0.0082 16.2 0.7 0.27 11.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OIR58689.1 - 0.017 15.6 0.1 0.068 13.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.12 OIR58689.1 - 0.039 14.0 1.1 1.1 9.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_12 PF13424.6 OIR58689.1 - 0.039 14.2 0.7 0.34 11.2 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Diphthamide_syn PF01866.17 OIR58690.1 - 1.9e-99 333.0 0.0 2.2e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Endopep_inhib PF16800.5 OIR58690.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor PTH2 PF01981.16 OIR58691.1 - 4.3e-41 139.9 0.8 5e-41 139.7 0.8 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 His_biosynth PF00977.21 OIR58691.1 - 0.036 13.5 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein ETRAMP PF09716.10 OIR58692.1 - 0.7 10.0 2.9 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF1150 PF06620.11 OIR58693.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) ELMO_CED12 PF04727.13 OIR58694.1 - 5.7e-28 98.2 0.0 9.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3350 PF11830.8 OIR58694.1 - 0.13 12.6 0.5 0.13 12.6 0.5 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) Arf PF00025.21 OIR58695.1 - 1.8e-33 115.5 0.0 2.2e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OIR58695.1 - 4.3e-12 46.3 0.0 5.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OIR58695.1 - 9.9e-12 44.7 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 OIR58695.1 - 7.3e-10 38.6 0.0 9.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OIR58695.1 - 7.4e-10 38.9 0.0 9.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OIR58695.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OIR58695.1 - 1.6e-06 27.6 0.0 0.00058 19.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 OIR58695.1 - 5.1e-05 22.9 0.0 0.0051 16.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 OIR58695.1 - 0.00026 20.8 0.0 0.023 14.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 OIR58695.1 - 0.0025 18.3 0.0 0.004 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR58695.1 - 0.0087 16.2 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OIR58695.1 - 0.011 14.8 0.0 0.04 12.9 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 OIR58695.1 - 0.027 15.0 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 OIR58695.1 - 0.038 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 OIR58695.1 - 0.04 14.0 0.0 0.25 11.4 0.0 1.9 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.6 OIR58695.1 - 0.057 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 OIR58695.1 - 0.061 12.4 0.1 0.2 10.7 0.0 1.8 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.12 OIR58695.1 - 0.062 13.2 0.0 0.97 9.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 OIR58695.1 - 0.067 13.6 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 OIR58695.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OIR58695.1 - 0.077 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 OIR58695.1 - 0.083 12.5 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OIR58695.1 - 0.095 12.6 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 OIR58695.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 OIR58695.1 - 0.12 12.0 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 OIR58695.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 OIR58695.1 - 0.13 12.0 0.0 5.7 6.7 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PARM PF17061.5 OIR58696.1 - 0.043 13.9 11.0 0.068 13.3 11.0 1.2 1 0 0 1 1 1 0 PARM Spore_III_AB PF09548.10 OIR58696.1 - 0.073 13.2 1.4 0.32 11.1 0.2 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TMPIT PF07851.13 OIR58696.1 - 0.37 10.0 3.2 0.58 9.4 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein tRNA-synt_1g PF09334.11 OIR58697.1 - 2.1e-143 477.8 0.0 3.1e-143 477.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OIR58697.1 - 8.8e-10 37.5 0.0 1.1e-07 30.6 0.0 3.3 3 1 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OIR58697.1 - 0.0011 18.3 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain C1_1 PF00130.22 OIR58697.1 - 9.2 6.2 7.0 4.1 7.4 1.5 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_1 PF00583.25 OIR58698.1 - 1.4e-12 47.8 0.1 1.8e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OIR58698.1 - 1.1e-11 44.8 0.1 1.4e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR58698.1 - 4e-07 30.4 0.2 5.7e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OIR58698.1 - 0.00044 20.9 0.0 0.00058 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OIR58698.1 - 0.021 14.9 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TRAP_beta PF05753.14 OIR58698.1 - 0.1 12.0 0.1 0.18 11.2 0.0 1.4 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) GPI-anchored PF10342.9 OIR58699.1 - 0.00026 21.7 0.0 0.00036 21.2 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SANTA PF09133.10 OIR58699.1 - 0.025 15.1 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 SANTA (SANT Associated) RRP7 PF12923.7 OIR58700.1 - 0.0023 18.0 0.1 0.003 17.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Adaptin_N PF01602.20 OIR58701.1 - 9e-75 252.2 0.0 1.1e-74 251.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OIR58701.1 - 7.2e-32 110.7 0.0 1.7e-29 102.9 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OIR58701.1 - 4.1e-11 43.1 0.4 0.00013 22.3 0.0 5.2 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 OIR58701.1 - 5.1e-06 26.3 0.2 0.038 14.2 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 OIR58701.1 - 0.035 14.6 0.7 3.1 8.4 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Cohesin_HEAT PF12765.7 OIR58701.1 - 0.043 14.1 0.3 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Rhamno_transf PF11316.8 OIR58702.1 - 0.035 13.5 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase Peptidase_S9_N PF02897.15 OIR58702.1 - 0.082 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Rep_fac_C PF08542.11 OIR58703.1 - 8.7e-15 54.9 0.0 1.8e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 OIR58703.1 - 2.4e-14 53.4 0.0 7.2e-11 42.1 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 OIR58703.1 - 1.9e-13 51.0 0.1 3.3e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OIR58703.1 - 2.3e-05 24.8 0.2 0.0031 17.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 OIR58703.1 - 2.5e-05 24.1 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 OIR58703.1 - 9.2e-05 22.5 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OIR58703.1 - 0.00052 20.3 0.2 0.31 11.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OIR58703.1 - 0.0015 18.3 0.0 0.004 16.9 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OIR58703.1 - 0.0015 18.8 0.0 0.0034 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 OIR58703.1 - 0.0023 17.9 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 OIR58703.1 - 0.0032 17.6 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OIR58703.1 - 0.0056 16.3 0.2 0.014 15.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OIR58703.1 - 0.011 15.1 0.1 0.14 11.5 0.1 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OIR58703.1 - 0.012 15.9 0.2 0.42 11.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 OIR58703.1 - 0.028 14.4 0.1 0.12 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 OIR58703.1 - 0.036 13.5 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 OIR58703.1 - 0.039 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 OIR58703.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 OIR58703.1 - 0.1 12.6 0.1 0.52 10.3 0.0 2.1 1 1 1 2 2 2 0 Flavivirus DEAD domain AAA_24 PF13479.6 OIR58703.1 - 0.15 11.7 0.0 0.43 10.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OIR58703.1 - 0.17 11.6 0.1 0.63 9.7 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 OIR58703.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Diphthami_syn_2 PF01902.17 OIR58704.1 - 6.1e-33 114.2 0.0 1.2e-32 113.2 0.0 1.4 1 1 0 1 1 1 1 Diphthamide synthase DNA_pol_E_B PF04042.16 OIR58705.1 - 1.8e-23 83.0 0.0 3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Il13Ra_Ig PF18001.1 OIR58706.1 - 0.027 14.5 0.1 0.073 13.2 0.1 1.7 2 0 0 2 2 2 0 Interleukin-13 receptor subunit alpha Ig-like domain DUF2418 PF10332.9 OIR58707.1 - 6.1e-19 68.3 0.1 1.9e-18 66.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) DUF3487 PF11990.8 OIR58707.1 - 0.035 14.0 2.3 2.3 8.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) Glyco_transf_8 PF01501.20 OIR58708.1 - 3.5e-09 36.6 0.0 7.2e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OIR58708.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative WD40 PF00400.32 OIR58709.1 - 1.5e-09 38.3 2.5 0.056 14.3 0.6 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58709.1 - 2.8e-05 24.3 0.0 0.0068 16.7 0.0 3.8 2 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OIR58709.1 - 0.039 12.5 0.0 0.14 10.6 0.0 1.7 1 1 1 2 2 2 0 Cytochrome D1 heme domain Sld5 PF05916.11 OIR58710.1 - 1.5e-15 57.6 0.0 1.9e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein MMR_HSR1 PF01926.23 OIR58712.1 - 3.7e-16 59.2 0.3 1.5e-14 54.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OIR58712.1 - 1.8e-08 34.1 0.4 2.3e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OIR58712.1 - 7.7e-08 32.4 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 OIR58712.1 - 0.0069 15.7 0.3 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 AIG1 family MeaB PF03308.16 OIR58712.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OIR58712.1 - 0.02 14.5 0.3 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OIR58712.1 - 0.037 14.4 0.2 0.41 11.0 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 OIR58712.1 - 0.043 13.4 0.1 7.5 6.0 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 OIR58712.1 - 0.072 13.6 2.5 0.3 11.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 OIR58712.1 - 0.88 9.6 4.9 0.29 11.2 0.2 2.5 2 2 1 3 3 3 0 Dynamin family YchF-GTPase_C PF06071.13 OIR58713.1 - 1.2e-38 131.2 0.5 4.2e-38 129.4 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OIR58713.1 - 6.6e-23 81.0 0.0 1.4e-21 76.7 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OIR58713.1 - 2.2e-07 30.5 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 OIR58713.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 OIR58713.1 - 0.14 12.2 0.0 21 5.1 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Peptidase_S24 PF00717.23 OIR58715.1 - 3.3e-09 36.6 0.1 5.2e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Pyrid_ox_like PF16242.5 OIR58715.1 - 0.013 15.1 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like BRO1 PF03097.18 OIR58716.1 - 6.2e-61 206.3 0.8 1.1e-60 205.5 0.8 1.4 1 0 0 1 1 1 1 BRO1-like domain DUF3408 PF11888.8 OIR58716.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3408) MA3 PF02847.17 OIR58717.1 - 1.7e-06 28.0 0.0 2e-05 24.5 0.0 2.8 3 1 0 3 3 3 1 MA3 domain Pex19 PF04614.12 OIR58717.1 - 0.09 12.5 0.0 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Pex19 protein family MIF4G PF02854.19 OIR58717.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 MIF4G domain V-ATPase_H_C PF11698.8 OIR58718.1 - 6.5e-32 110.1 0.1 1.3e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 OIR58718.1 - 1.1e-25 90.6 0.1 2.8e-25 89.3 0.1 1.6 2 0 0 2 2 2 1 V-ATPase subunit H TP_methylase PF00590.20 OIR58720.1 - 3.6e-17 63.0 0.1 5.6e-17 62.4 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-RVT PF13966.6 OIR58722.1 - 0.0012 19.5 0.1 0.0024 18.6 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3399 PF11879.8 OIR58722.1 - 0.32 11.3 2.8 11 6.5 2.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) Glyco_transf_15 PF01793.16 OIR58723.1 - 9.2e-108 360.3 8.9 1.2e-107 360.0 8.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rad17 PF03215.15 OIR58724.1 - 2.1e-06 27.8 0.0 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta2 PF13177.6 OIR58724.1 - 4e-06 26.7 0.0 1.1e-05 25.3 0.0 1.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OIR58724.1 - 0.0092 16.4 0.1 0.036 14.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 OIR58724.1 - 0.024 15.1 0.0 0.07 13.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 OIR58724.1 - 0.038 14.3 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA C-terminal domain AAA_22 PF13401.6 OIR58724.1 - 0.039 14.2 1.0 0.19 12.0 0.5 2.4 2 2 0 2 2 2 0 AAA domain Methyltransf_4 PF02390.17 OIR58724.1 - 0.092 12.2 0.0 3.9 6.9 0.0 2.6 2 1 1 3 3 3 0 Putative methyltransferase RuvB_N PF05496.12 OIR58724.1 - 0.095 12.4 0.1 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 OIR58725.1 - 7.4e-10 39.4 0.2 2.2e-09 37.8 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OIR58725.1 - 6.3e-06 26.7 0.1 1.5e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 OIR58725.1 - 9.3e-06 26.0 0.6 0.0038 17.5 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 OIR58725.1 - 1.2e-05 25.6 0.5 0.00035 20.8 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OIR58725.1 - 0.00026 21.0 0.1 0.0005 20.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OIR58725.1 - 0.00073 19.1 0.2 0.0029 17.2 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 OIR58725.1 - 0.00088 19.3 0.2 0.0022 18.0 0.2 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DAP3 PF10236.9 OIR58725.1 - 0.00091 18.5 0.1 0.0041 16.3 0.1 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.25 OIR58725.1 - 0.0012 18.6 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.15 OIR58725.1 - 0.0044 17.1 0.2 0.013 15.5 0.2 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OIR58725.1 - 0.017 14.9 0.2 0.041 13.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 OIR58725.1 - 0.018 14.1 0.0 0.044 12.8 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 OIR58725.1 - 0.019 14.2 0.1 0.046 13.0 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OIR58725.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OIR58725.1 - 0.049 13.4 0.5 0.11 12.2 0.5 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 OIR58725.1 - 0.054 12.6 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RFX_DNA_binding PF02257.15 OIR58725.1 - 0.056 14.1 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain NACHT PF05729.12 OIR58725.1 - 0.065 13.1 0.1 0.24 11.3 0.1 2.0 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 OIR58725.1 - 0.066 13.6 0.1 0.16 12.4 0.1 1.8 1 1 0 1 1 1 0 RNA helicase Helicase_RecD PF05127.14 OIR58725.1 - 0.094 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase Stk19 PF10494.9 OIR58725.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 AAA_28 PF13521.6 OIR58725.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 OIR58725.1 - 0.16 10.7 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain eIF3_subunit PF08597.10 OIR58726.1 - 0.055 13.4 28.5 0.055 13.4 14.9 3.0 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit PGM_PMM_I PF02878.16 OIR58727.1 - 8.3e-21 74.2 0.0 2.1e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OIR58727.1 - 5.5e-11 42.7 0.0 9.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OIR58727.1 - 2.7e-10 40.8 0.0 6.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II BACK PF07707.15 OIR58727.1 - 0.038 14.1 0.4 0.11 12.6 0.4 1.8 1 0 0 1 1 1 0 BTB And C-terminal Kelch DUF4217 PF13959.6 OIR58728.1 - 0.00019 21.6 0.0 0.00038 20.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 OIR58728.1 - 0.0019 18.5 0.0 0.14 12.5 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OIR58728.1 - 0.079 12.7 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Rho_N PF07498.12 OIR58728.1 - 0.13 12.2 0.9 3.6 7.6 0.1 2.7 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain DSHCT PF08148.12 OIR58730.1 - 1.9e-55 187.0 0.3 1.9e-55 187.0 0.3 2.7 2 1 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 OIR58730.1 - 2e-19 70.1 0.0 5.8e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 OIR58730.1 - 3e-12 47.0 17.7 8.8e-11 42.2 14.4 2.9 2 1 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 OIR58730.1 - 1.5e-06 28.5 0.0 1.5e-05 25.3 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Vps39_1 PF10366.9 OIR58730.1 - 0.011 16.0 0.6 0.08 13.2 0.3 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 AAA_19 PF13245.6 OIR58730.1 - 0.018 15.4 0.7 0.068 13.5 0.3 2.2 2 0 0 2 2 2 0 AAA domain CobU PF02283.16 OIR58730.1 - 0.039 13.5 1.1 3.5 7.2 0.0 3.7 4 0 0 4 4 4 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.6 OIR58730.1 - 0.083 13.2 1.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain YvfG PF09628.10 OIR58730.1 - 0.27 11.6 1.1 0.62 10.5 0.3 2.1 2 0 0 2 2 2 0 YvfG protein RAP1 PF07218.11 OIR58731.1 - 0.78 7.9 19.5 1.1 7.4 19.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 OIR58731.1 - 4.2 6.1 13.5 4.2 6.1 13.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain tRNA_bind PF01588.20 OIR58732.1 - 4e-15 55.7 0.3 4.7e-15 55.5 0.3 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain BCIP PF13862.6 OIR58733.1 - 4e-13 49.6 0.0 8.2e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 p21-C-terminal region-binding protein SUI1 PF01253.22 OIR58734.1 - 8.4e-16 58.3 0.4 1.1e-15 57.9 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Inos-1-P_synth PF01658.17 OIR58734.1 - 0.095 13.0 1.3 0.14 12.4 1.3 1.3 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase RGS_DHEX PF18148.1 OIR58735.1 - 0.0024 18.0 0.0 3 8.0 0.0 2.3 2 0 0 2 2 2 2 Regulator of G-protein signalling DHEX domain DUF2515 PF10720.9 OIR58735.1 - 0.11 11.6 0.1 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) WD40 PF00400.32 OIR58736.1 - 4.1e-32 109.7 16.2 2.4e-09 37.7 2.7 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58736.1 - 9.9e-13 48.2 0.0 0.065 13.5 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OIR58736.1 - 0.00018 20.6 0.6 0.14 11.1 0.0 3.6 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 OIR58736.1 - 0.0012 18.0 0.5 0.019 14.1 0.0 2.5 2 1 0 3 3 3 1 Protein of unknown function (DUF1513) WD40_like PF17005.5 OIR58736.1 - 0.027 13.8 0.0 0.4 10.0 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 OIR58736.1 - 8.1 7.1 7.7 7.7 7.1 0.1 3.9 5 0 0 5 5 5 0 PQQ-like domain DUF902 PF06001.13 OIR58738.1 - 0.2 12.2 0.2 0.32 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) zf-C3HC4_3 PF13920.6 OIR58739.1 - 0.21 11.5 7.2 0.39 10.6 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.6 OIR58740.1 - 1.7e-06 28.4 0.3 1.8e-05 25.1 0.0 2.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 OIR58740.1 - 2.1e-06 27.2 0.7 0.57 10.2 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OIR58740.1 - 7.9e-05 21.9 5.4 0.24 11.0 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 OIR58740.1 - 0.052 13.4 0.1 8.9 6.2 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair Imm44 PF15571.6 OIR58741.1 - 0.011 16.0 0.7 4.6 7.5 0.0 4.2 4 2 2 6 6 6 0 Immunity protein 44 MAPKK1_Int PF08923.10 OIR58741.1 - 0.08 12.8 0.0 0.46 10.3 0.0 2.3 3 0 0 3 3 3 0 Mitogen-activated protein kinase kinase 1 interacting Mitoc_mL59 PF18126.1 OIR58742.1 - 0.018 15.3 0.3 0.025 14.9 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 DivIC PF04977.15 OIR58742.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Actin PF00022.19 OIR58743.1 - 1.9e-83 280.3 0.0 1.8e-50 171.7 0.0 2.0 1 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 OIR58743.1 - 7.4e-09 34.9 0.0 1.3e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 MreB/Mbl protein PhoLip_ATPase_C PF16212.5 OIR58744.1 - 5.9e-38 131.0 18.0 5.9e-38 131.0 18.0 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OIR58744.1 - 1.2e-14 53.7 0.2 3.4e-14 52.3 0.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 OIR58744.1 - 4.5e-14 52.4 0.3 4.5e-14 52.4 0.3 3.4 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OIR58744.1 - 1.9e-13 51.2 0.5 2.9e-07 31.0 0.7 3.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OIR58744.1 - 3e-07 30.4 0.0 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OIR58744.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hexokinase_1 PF00349.21 OIR58746.1 - 2.5e-60 203.8 0.1 3.8e-60 203.2 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OIR58746.1 - 8.9e-49 166.1 0.0 1.6e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Lipase_3 PF01764.25 OIR58749.1 - 2.3e-19 69.7 0.0 4.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 OIR58749.1 - 0.033 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OIR58749.1 - 0.2 11.3 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein FHA_2 PF17913.1 OIR58750.1 - 0.0056 16.9 0.0 37 4.6 0.0 4.0 3 1 1 4 4 4 0 FHA domain Glycoprotein_B PF00606.18 OIR58750.1 - 0.0075 15.7 1.5 5.8 6.3 0.0 3.7 3 1 1 4 4 4 2 Herpesvirus Glycoprotein B ectodomain Sep15_SelM PF08806.11 OIR58750.1 - 0.013 15.6 0.5 14 5.9 0.0 3.5 3 0 0 3 3 3 0 Sep15/SelM redox domain TTRAP PF14203.6 OIR58750.1 - 0.04 13.9 6.0 7.5 6.6 0.0 4.1 4 0 0 4 4 4 0 Putative tranposon-transfer assisting protein DUF2001 PF09393.10 OIR58750.1 - 0.13 12.3 0.1 25 4.9 0.0 2.4 2 0 0 2 2 2 0 Phage tail tube protein Cation_ATPase_N PF00690.26 OIR58751.1 - 0.023 14.4 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Radical_SAM_C PF16199.5 OIR58753.1 - 6.3e-31 106.2 0.1 1.4e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OIR58753.1 - 7.2e-15 55.8 0.2 1.2e-13 51.8 0.4 2.3 1 1 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OIR58753.1 - 1.7e-10 41.1 0.1 3.5e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OIR58753.1 - 3.1e-05 23.9 0.2 9.4e-05 22.4 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR58753.1 - 0.058 13.8 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA_bind PF01588.20 OIR58754.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.6 2 0 0 2 2 2 0 Putative tRNA binding domain FliMN_C PF01052.20 OIR58754.1 - 0.041 13.9 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term RIO1 PF01163.22 OIR58755.1 - 1.3e-12 47.7 0.1 1.7e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 OIR58755.1 - 1.3e-11 44.4 0.1 1.5e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 OIR58755.1 - 2.1e-10 40.9 1.8 1.6e-05 25.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OIR58755.1 - 3.3e-07 29.9 0.0 5.6e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase WaaY PF06176.11 OIR58755.1 - 8.8e-07 28.8 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 OIR58755.1 - 1.4e-06 27.8 0.9 1.6e-05 24.4 0.9 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OIR58755.1 - 0.0012 18.5 0.1 0.012 15.2 0.1 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase Acetyltransf_13 PF13880.6 OIR58756.1 - 2.3e-21 75.5 0.1 4.1e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OIR58756.1 - 1.4e-08 34.4 2.6 3e-08 33.3 2.6 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 OIR58756.1 - 0.00086 19.7 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OIR58756.1 - 0.031 14.5 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Tim17 PF02466.19 OIR58757.1 - 3.7e-06 27.3 0.8 4.8e-06 26.9 0.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family GP3_package PF16677.5 OIR58757.1 - 0.15 12.2 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA-packaging protein gp3 Thymidylate_kin PF02223.17 OIR58758.1 - 7.1e-43 146.4 0.0 8.1e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase DUF463 PF04317.12 OIR58758.1 - 0.0022 17.0 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 YcjX-like family, DUF463 PPK2 PF03976.14 OIR58758.1 - 0.01 15.3 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) MobB PF03205.14 OIR58758.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.6 OIR58759.1 - 2.9e-17 62.8 0.0 4.7e-07 30.1 0.0 3.8 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 OIR58759.1 - 3.8e-13 48.8 0.0 0.014 16.0 0.0 6.1 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat E1-E2_ATPase PF00122.20 OIR58760.1 - 1.8e-27 96.1 0.2 1.8e-27 96.1 0.2 2.1 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 OIR58760.1 - 5e-17 62.9 1.4 1.7e-16 61.2 1.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OIR58760.1 - 9.8e-17 60.8 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 OIR58760.1 - 2.4e-06 27.4 0.5 2.4e-06 27.4 0.5 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 OIR58760.1 - 0.00094 19.0 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallothi_Euk2 PF12809.7 OIR58760.1 - 0.11 12.8 2.2 0.35 11.2 2.2 1.8 1 0 0 1 1 1 0 Eukaryotic metallothionein ELP6 PF09807.9 OIR58761.1 - 2.9e-11 43.3 1.5 3.2e-09 36.6 0.6 2.2 1 1 1 2 2 2 2 Elongation complex protein 6 Fn_bind PF02986.14 OIR58761.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Fibronectin binding repeat MEDS PF14417.6 OIR58761.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DEAD PF00270.29 OIR58762.1 - 1.4e-37 129.2 0.1 2.9e-37 128.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58762.1 - 6e-22 78.1 0.6 8.7e-21 74.3 0.1 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58762.1 - 4.2e-11 43.1 1.0 8.1e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zot PF05707.12 OIR58762.1 - 0.034 13.8 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Inhibitor_I78 PF11720.8 OIR58763.1 - 0.0006 19.8 0.0 0.00067 19.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 OIR58763.1 - 0.081 13.6 0.0 0.1 13.3 0.0 1.2 1 0 0 1 1 1 0 Potato inhibitor I family PGK PF00162.19 OIR58764.1 - 1.9e-122 408.9 0.0 2.2e-122 408.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase AA_permease_2 PF13520.6 OIR58766.1 - 8.4e-45 153.4 43.3 9.3e-45 153.2 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OIR58766.1 - 9.2e-18 64.1 40.2 1.2e-17 63.8 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease PSI PF01437.25 OIR58767.1 - 0.025 15.1 3.6 0.054 14.0 3.6 1.5 1 0 0 1 1 1 0 Plexin repeat Syja_N PF02383.18 OIR58769.1 - 9.2e-56 189.5 0.2 1.3e-55 189.0 0.2 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 OIR58769.1 - 3.3e-08 33.3 0.0 5.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF974 PF06159.13 OIR58770.1 - 0.00085 19.2 0.9 0.18 11.5 0.1 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF974) Transglut_C PF00927.22 OIR58770.1 - 0.25 11.5 1.0 0.65 10.2 0.1 2.1 3 0 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain WD40 PF00400.32 OIR58772.1 - 1.6e-09 38.2 11.9 0.0004 21.1 0.7 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OIR58772.1 - 6.5e-05 22.0 0.1 0.00052 19.1 0.0 2.0 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 OIR58772.1 - 0.0011 19.2 0.1 1.3 9.4 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain vATP-synt_E PF01991.18 OIR58773.1 - 1.7e-36 125.6 12.6 2.7e-36 124.9 12.6 1.3 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RHH_6 PF16762.5 OIR58773.1 - 0.023 15.3 0.0 0.08 13.6 0.0 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix domain Peptidase_C65 PF10275.9 OIR58774.1 - 1.7e-42 145.6 0.0 2.1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 OIR58774.1 - 5.1e-06 27.0 0.0 0.00021 21.8 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease EMP24_GP25L PF01105.24 OIR58776.1 - 6.3e-40 137.0 0.6 7.2e-40 136.9 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3203 PF11462.8 OIR58776.1 - 0.026 14.7 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) FlaG PF03646.15 OIR58776.1 - 0.032 14.4 0.7 0.054 13.7 0.7 1.3 1 0 0 1 1 1 0 FlaG protein Dynein_C PF18199.1 OIR58776.1 - 0.057 12.6 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain Flp_N PF03930.14 OIR58776.1 - 0.061 13.3 0.2 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus Peptidase_M15_2 PF05951.13 OIR58776.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) PH PF00169.29 OIR58777.1 - 7.4e-21 74.6 2.5 5.7e-14 52.5 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 OIR58777.1 - 1.1e-06 28.8 0.4 1.5e-05 25.2 0.1 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 OIR58777.1 - 2.6e-06 27.8 9.2 1.1e-05 25.8 0.2 3.4 4 1 0 4 4 4 2 Pleckstrin homology domain PH_2 PF08458.10 OIR58777.1 - 0.003 17.9 3.1 0.53 10.7 0.0 3.0 2 1 1 3 3 3 2 Plant pleckstrin homology-like region PH_9 PF15410.6 OIR58777.1 - 0.0079 16.6 6.0 0.11 12.8 0.1 4.0 2 2 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 OIR58777.1 - 0.028 14.2 8.3 0.63 9.8 1.6 3.0 2 2 1 3 3 3 0 Pleckstrin homology domain TALPID3 PF15324.6 OIR58777.1 - 1.7 6.3 4.2 2.1 5.9 4.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Gti1_Pac2 PF09729.9 OIR58778.1 - 2e-28 99.7 0.1 3.8e-26 92.3 0.1 2.5 1 1 0 1 1 1 1 Gti1/Pac2 family AT_hook PF02178.19 OIR58778.1 - 0.12 12.4 6.2 0.49 10.4 6.2 2.2 1 0 0 1 1 1 0 AT hook motif NGP1NT PF08153.12 OIR58779.1 - 1.9e-40 138.0 2.8 3.7e-40 137.1 2.8 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OIR58779.1 - 1.3e-20 73.6 0.3 1.4e-15 57.3 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OIR58779.1 - 1.9e-09 37.3 0.1 3.6e-08 33.1 0.1 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OIR58779.1 - 5e-06 26.7 2.6 0.014 15.4 0.1 3.8 3 1 1 4 4 4 1 Dynamin family RsgA_GTPase PF03193.16 OIR58779.1 - 2.8e-05 24.1 0.0 0.00012 22.0 0.0 2.3 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 OIR58779.1 - 0.00021 20.9 0.2 0.75 9.3 0.0 3.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FAM181 PF15238.6 OIR58779.1 - 0.0038 17.1 0.7 0.0056 16.6 0.7 1.2 1 0 0 1 1 1 1 FAM181 AIG1 PF04548.16 OIR58779.1 - 0.012 14.9 0.1 0.012 14.9 0.1 1.8 2 0 0 2 2 2 0 AIG1 family Arf PF00025.21 OIR58779.1 - 0.018 14.5 0.0 0.94 8.9 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family ABC_tran PF00005.27 OIR58779.1 - 0.031 14.8 1.0 1.4 9.5 0.0 3.0 2 1 1 3 3 3 0 ABC transporter cobW PF02492.19 OIR58779.1 - 0.085 12.4 0.0 0.58 9.7 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OIR58779.1 - 0.11 11.4 0.1 0.28 10.1 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OIR58779.1 - 0.12 12.9 0.5 1.4 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain EF-hand_7 PF13499.6 OIR58780.1 - 5.9e-18 65.1 8.6 1.7e-09 38.0 1.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OIR58780.1 - 9.7e-16 56.1 8.0 0.00023 20.5 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OIR58780.1 - 1.1e-10 40.5 4.2 0.00096 18.9 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OIR58780.1 - 3.6e-10 39.5 11.8 0.00012 21.8 0.7 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OIR58780.1 - 6.2e-09 35.0 9.2 0.0001 21.6 0.3 4.4 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OIR58780.1 - 6.3e-06 26.4 0.3 0.031 14.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OIR58780.1 - 6.9e-05 23.1 0.2 0.0089 16.3 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 OIR58780.1 - 0.00013 22.8 0.2 0.056 14.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain DUF2666 PF10869.8 OIR58780.1 - 0.0057 16.9 0.1 2.2 8.5 0.1 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF2666) Caleosin PF05042.13 OIR58780.1 - 0.0087 16.0 1.4 4.4 7.2 0.1 3.1 1 1 2 3 3 3 2 Caleosin related protein Sybindin PF04099.12 OIR58781.1 - 1.1e-25 90.2 0.1 1.3e-25 90.0 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OIR58781.1 - 7e-06 26.2 0.1 8.2e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MIF4G PF02854.19 OIR58782.1 - 0.011 15.4 6.4 0.059 13.0 0.0 4.1 4 1 1 5 5 5 0 MIF4G domain Tae4 PF14113.6 OIR58782.1 - 0.034 14.4 0.4 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 CBFNT PF08143.11 OIR58782.1 - 0.29 12.6 2.5 24 6.5 0.1 2.4 2 0 0 2 2 2 0 CBFNT (NUC161) domain SapB_1 PF05184.15 OIR58782.1 - 1.8 8.7 6.1 18 5.4 0.3 4.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 WD40 PF00400.32 OIR58783.1 - 3.1e-22 78.4 0.3 0.0038 18.0 0.0 6.9 6 1 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58783.1 - 1e-07 32.1 0.1 0.00089 19.5 0.0 3.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OIR58783.1 - 0.00081 19.0 0.0 0.018 14.6 0.1 2.1 2 0 0 2 2 2 1 PQQ-like domain CPSF_A PF03178.15 OIR58783.1 - 0.014 14.7 0.0 2.7 7.2 0.0 3.2 3 1 0 3 3 3 0 CPSF A subunit region RRM_1 PF00076.22 OIR58784.1 - 5.7e-17 61.3 0.0 8.9e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 OIR58784.1 - 6e-08 32.4 2.3 6e-08 32.4 2.3 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 OIR58784.1 - 9.3e-05 22.2 2.2 0.00021 21.0 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Nup35_RRM_2 PF14605.6 OIR58784.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.6 OIR58784.1 - 0.0056 16.6 0.6 0.011 15.7 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OIR58784.1 - 0.0073 16.0 3.3 0.016 14.9 3.3 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RRM_7 PF16367.5 OIR58784.1 - 0.019 15.1 0.0 0.054 13.6 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif Sua5_yciO_yrdC PF01300.18 OIR58785.1 - 9.7e-45 152.3 0.0 1.5e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OIR58785.1 - 2e-18 67.2 0.0 2.8e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF5374 PF17344.2 OIR58785.1 - 0.011 15.6 0.2 0.027 14.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5374) PTR2 PF00854.21 OIR58786.1 - 1.9e-68 231.1 26.1 5.8e-67 226.2 25.4 2.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OIR58786.1 - 6.2e-05 22.1 40.5 6.2e-05 22.1 40.5 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily Proteasome PF00227.26 OIR58787.1 - 2.3e-39 134.9 0.0 2.6e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SAB PF04382.13 OIR58787.1 - 0.033 14.3 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 SAB domain Mei5_like PF17021.5 OIR58788.1 - 0.0012 18.8 1.2 0.0016 18.5 1.2 1.2 1 0 0 1 1 1 1 Putative double-strand recombination repair-like DUF349 PF03993.12 OIR58788.1 - 0.81 10.0 8.7 0.82 10.0 7.7 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) ubiquitin PF00240.23 OIR58789.1 - 1.9e-09 37.1 0.1 3.2e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OIR58789.1 - 1.9e-07 30.9 0.0 6.5e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 OIR58789.1 - 0.0063 16.4 14.4 0.014 15.3 7.7 2.4 1 1 1 2 2 2 1 STI1 domain TBK1_ULD PF18396.1 OIR58789.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain UPF0242 PF06785.11 OIR58789.1 - 0.028 14.6 1.1 0.077 13.1 1.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HOIP-UBA PF16678.5 OIR58789.1 - 0.03 14.3 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 OIR58789.1 - 0.5 10.3 13.2 55 3.8 13.0 2.3 1 1 0 1 1 1 0 Spore germination GerD central core domain Ras PF00071.22 OIR58790.1 - 2.2e-61 206.2 0.1 2.6e-61 206.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR58790.1 - 2.4e-36 124.6 0.0 7.2e-36 123.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR58790.1 - 3.7e-15 55.8 0.0 4.4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OIR58790.1 - 1.6e-07 31.4 0.6 0.0025 17.7 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OIR58790.1 - 8.3e-06 25.5 0.1 4.3e-05 23.2 0.1 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 OIR58790.1 - 1.4e-05 24.7 0.0 0.00016 21.2 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 OIR58790.1 - 1.5e-05 24.5 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OIR58790.1 - 2.6e-05 24.2 0.0 4.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 OIR58790.1 - 5.3e-05 23.1 0.0 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 OIR58790.1 - 5.9e-05 22.6 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 OIR58790.1 - 0.0095 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein AAA_16 PF13191.6 OIR58790.1 - 0.018 15.4 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OIR58790.1 - 0.026 14.3 0.3 0.051 13.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1_Xtn PF16897.5 OIR58790.1 - 0.029 14.4 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_24 PF13479.6 OIR58790.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OIR58790.1 - 0.05 13.9 0.0 0.91 9.8 0.0 2.3 1 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OIR58790.1 - 0.076 12.8 0.2 6.5 6.5 0.1 2.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 OIR58790.1 - 0.088 11.9 0.0 0.44 9.6 0.0 1.9 1 1 0 2 2 2 0 MCM P-loop domain AAA_5 PF07728.14 OIR58790.1 - 0.088 12.8 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OIR58790.1 - 0.14 12.7 0.5 0.28 11.7 0.5 1.8 1 1 0 1 1 1 0 ABC transporter Hamartin PF04388.12 OIR58791.1 - 0.085 11.5 17.4 0.1 11.3 17.4 1.2 1 0 0 1 1 1 0 Hamartin protein AAA_15 PF13175.6 OIR58791.1 - 0.096 12.4 29.0 0.12 12.0 29.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Gp_dh_N PF00044.24 OIR58791.1 - 0.13 12.6 0.8 0.33 11.3 0.8 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LMBR1 PF04791.16 OIR58791.1 - 0.18 10.7 16.7 0.21 10.4 16.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.9 OIR58791.1 - 0.46 8.7 20.2 0.58 8.4 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.6 OIR58791.1 - 2.2 7.8 31.5 3.4 7.2 31.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SOBP PF15279.6 OIR58791.1 - 2.6 8.6 20.3 3.3 8.2 20.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CRT10 PF08728.10 OIR58791.1 - 4.3 5.4 17.3 4.5 5.3 17.3 1.0 1 0 0 1 1 1 0 CRT10 GREB1 PF15782.5 OIR58791.1 - 9.7 3.2 17.7 11 2.9 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF913 PF06025.12 OIR58792.1 - 3.2e-41 141.5 4.8 1.1e-40 139.8 0.7 3.5 3 1 2 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 OIR58792.1 - 8.5e-10 38.6 0.1 1.5e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) RINGv PF12906.7 OIR58793.1 - 6.9e-09 35.7 10.1 1.2e-08 34.9 10.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-CSL PF05207.13 OIR58793.1 - 0.041 13.6 0.6 5.6 6.8 0.2 2.5 2 0 0 2 2 2 0 CSL zinc finger Hydrolase_4 PF12146.8 OIR58794.1 - 3.2e-09 36.4 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OIR58794.1 - 0.00079 20.1 0.0 0.00096 19.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Urm1 PF09138.11 OIR58795.1 - 1.5e-15 57.3 0.0 1.7e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 OIR58795.1 - 7.7e-06 26.5 0.0 8.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ThiS family DUF3060 PF11259.8 OIR58796.1 - 1.4e-23 82.4 12.6 1.2e-07 31.3 0.1 6.0 5 1 1 6 6 6 5 Protein of unknown function (DUF3060) YabP PF07873.11 OIR58796.1 - 0.0013 18.4 0.1 0.0063 16.3 0.1 2.2 1 0 0 1 1 1 1 YabP family Na_trans_assoc PF06512.13 OIR58796.1 - 0.71 10.1 3.7 0.75 10.0 1.7 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated GCP_C_terminal PF04130.13 OIR58797.1 - 5.4e-40 137.8 0.1 1e-39 136.8 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OIR58797.1 - 1.8e-37 129.6 0.0 2.9e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DSHCT PF08148.12 OIR58798.1 - 3.4e-39 134.1 0.3 7.6e-39 133.0 0.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OIR58798.1 - 5.2e-18 65.4 0.0 1.2e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 OIR58798.1 - 7.9e-12 45.7 0.0 2.9e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 OIR58798.1 - 2e-07 31.3 0.0 5.9e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58798.1 - 0.00016 21.7 0.1 0.00035 20.6 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OIR58798.1 - 0.062 13.6 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain CTP_synth_N PF06418.14 OIR58799.1 - 3.6e-85 285.5 0.1 4.7e-85 285.1 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OIR58799.1 - 1.7e-35 122.5 0.0 6e-35 120.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OIR58799.1 - 0.055 13.2 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 Peptidase C26 SANTA PF09133.10 OIR58800.1 - 3e-16 59.7 0.0 7.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 SANTA (SANT Associated) Vps54_N PF10475.9 OIR58801.1 - 1.5e-08 34.3 7.0 1.8e-08 34.1 7.0 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex MeMO_Hyd_G PF02964.16 OIR58801.1 - 0.0089 16.0 2.9 0.015 15.3 2.9 1.3 1 0 0 1 1 1 1 Methane monooxygenase, hydrolase gamma chain MNE1 PF13762.6 OIR58801.1 - 1.2 9.1 4.2 0.58 10.1 1.1 1.9 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component Dynein_light PF01221.18 OIR58801.1 - 1.7 9.0 6.5 2.3 8.6 1.4 2.8 2 2 1 3 3 3 0 Dynein light chain type 1 Cid2 PF09774.9 OIR58801.1 - 2.9 8.3 11.4 0.25 11.8 4.3 2.5 1 1 1 2 2 2 0 Caffeine-induced death protein 2 SapB_1 PF05184.15 OIR58801.1 - 4.7 7.3 0.0 4.7 7.3 0.0 4.2 5 0 0 5 5 5 0 Saposin-like type B, region 1 ALMT PF11744.8 OIR58801.1 - 5.2 5.8 9.2 6.3 5.5 9.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cauli_AT PF03233.13 OIR58801.1 - 8.5 6.3 9.6 2 8.3 4.1 2.4 2 1 1 3 3 3 0 Aphid transmission protein DUF1104 PF06518.11 OIR58801.1 - 8.6 6.8 14.9 0.85 10.0 9.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) NAC PF01849.18 OIR58802.1 - 8e-08 32.1 0.2 1.6e-07 31.2 0.2 1.5 1 0 0 1 1 1 1 NAC domain NMT_C PF02799.15 OIR58802.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 1 1 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF573 PF04504.14 OIR58803.1 - 1.6 9.5 4.6 6.3 7.5 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Sec34 PF04136.15 OIR58803.1 - 3 7.7 6.7 5.1 7.0 1.0 2.3 1 1 1 2 2 2 0 Sec34-like family LSM PF01423.22 OIR58804.1 - 2.1e-15 56.1 0.0 2.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OIR58804.1 - 0.00018 21.6 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OIR58804.1 - 0.15 12.2 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Scd6-like Sm domain DUF5600 PF18150.1 OIR58806.1 - 5.5e-19 68.7 4.1 1.4e-18 67.4 4.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 OIR58806.1 - 1.6e-10 41.3 7.3 2.1e-10 40.9 0.0 3.3 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 OIR58806.1 - 2.2e-08 34.2 0.0 6.2e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.7 OIR58806.1 - 3.6e-06 26.9 0.0 9.3e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 OIR58806.1 - 4.5e-05 23.3 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Ras PF00071.22 OIR58806.1 - 0.0027 17.3 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 Ras family SBDS PF01172.18 OIR58806.1 - 0.011 15.8 0.1 0.038 14.1 0.1 1.9 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein EF-hand_7 PF13499.6 OIR58806.1 - 0.075 13.5 0.7 0.43 11.1 0.1 2.7 3 1 0 3 3 3 0 EF-hand domain pair ESCRT-II PF05871.12 OIR58806.1 - 0.086 13.1 1.2 0.34 11.2 0.2 2.2 2 0 0 2 2 2 0 ESCRT-II complex subunit Matrilin_ccoil PF10393.9 OIR58806.1 - 0.57 10.1 5.5 0.59 10.0 0.5 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin ECH_2 PF16113.5 OIR58807.1 - 0.048 13.1 0.4 0.066 12.7 0.4 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Imm-NTF2 PF15655.6 OIR58807.1 - 0.1 12.9 3.2 0.2 11.9 2.5 1.9 1 1 1 2 2 2 0 NTF2 fold immunity protein PP_kinase_N PF13089.6 OIR58807.1 - 0.53 10.6 4.0 0.75 10.2 0.1 2.2 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain SCA7 PF08313.12 OIR58808.1 - 1.4e-15 57.0 1.8 4.6e-15 55.3 0.3 2.3 1 1 1 2 2 2 1 SCA7, zinc-binding domain HMG_box PF00505.19 OIR58809.1 - 3e-06 27.6 3.6 7.7e-06 26.2 3.6 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box AIB PF15334.6 OIR58809.1 - 0.072 12.4 1.1 0.11 11.8 1.1 1.5 1 1 0 1 1 1 0 Aurora kinase A and ninein interacting protein Pkinase PF00069.25 OIR58810.1 - 4e-60 203.4 0.0 4.6e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58810.1 - 7.5e-31 107.3 0.0 9.6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OIR58810.1 - 3e-05 23.1 0.0 0.0017 17.4 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 OIR58810.1 - 0.00041 19.8 0.0 0.00094 18.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OIR58810.1 - 0.0036 16.7 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OIR58810.1 - 0.0079 16.1 0.0 0.094 12.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RNase_PH PF01138.21 OIR58811.1 - 4.2e-16 59.6 0.0 5.9e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 HMG_box PF00505.19 OIR58812.1 - 0.0013 19.1 3.0 0.0013 19.1 3.0 2.0 2 1 0 2 2 2 1 HMG (high mobility group) box SUFU_C PF12470.8 OIR58812.1 - 0.32 11.0 4.8 0.08 13.0 1.8 1.6 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain IKI3 PF04762.12 OIR58813.1 - 7.2e-87 292.4 3.3 4.3e-47 160.7 0.1 3.1 1 1 1 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 OIR58813.1 - 0.0013 19.0 0.2 22 5.4 0.0 5.2 3 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain MeMO_Hyd_G PF02964.16 OIR58813.1 - 0.016 15.2 0.0 3.2 7.7 0.1 3.0 3 0 0 3 3 3 0 Methane monooxygenase, hydrolase gamma chain PPR PF01535.20 OIR58813.1 - 7.7 7.0 6.9 42 4.7 0.1 4.1 5 0 0 5 5 5 0 PPR repeat EB1 PF03271.17 OIR58814.1 - 4e-15 55.8 2.0 1.2e-14 54.2 2.0 1.9 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OIR58814.1 - 1.9e-07 31.2 0.3 3.6e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain MOR2-PAG1_C PF14225.6 OIR58814.1 - 0.062 13.2 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis C-terminal FYVE PF01363.21 OIR58815.1 - 0.025 14.7 10.0 0.025 14.7 10.0 2.3 1 1 1 2 2 2 0 FYVE zinc finger Nup54 PF13874.6 OIR58816.1 - 5.4e-12 46.0 0.9 5.4e-12 46.0 0.9 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 UPF0184 PF03670.13 OIR58818.1 - 0.012 15.9 0.3 0.03 14.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Mce4_CUP1 PF11887.8 OIR58818.1 - 0.15 11.5 1.4 12 5.3 0.1 2.1 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF948 PF06103.11 OIR58818.1 - 0.36 11.1 5.3 8.3 6.7 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 OIR58818.1 - 0.41 9.5 23.2 0.73 8.6 23.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Acyl-CoA_dh_2 PF08028.11 OIR58818.1 - 0.67 10.2 2.9 3.7 7.8 2.4 2.2 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF5089 PF17002.5 OIR58818.1 - 0.7 9.7 31.0 0.088 12.7 23.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) XhlA PF10779.9 OIR58818.1 - 2.6 8.3 17.8 2.5 8.4 4.6 4.3 2 2 1 3 3 3 0 Haemolysin XhlA Mis12 PF05859.12 OIR58818.1 - 9.6 6.3 12.7 0.29 11.2 1.0 3.1 1 1 2 3 3 3 0 Mis12 protein BOP1NT PF08145.12 OIR58819.1 - 3.3e-50 171.4 5.2 3.3e-50 171.4 5.2 1.9 1 1 1 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 OIR58819.1 - 3.2e-10 40.4 2.5 0.011 16.6 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat PHD_like PF12910.7 OIR58819.1 - 0.026 14.5 0.4 0.059 13.4 0.1 1.7 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Rav1p_C PF12234.8 OIR58819.1 - 0.59 8.5 3.9 1.2 7.5 0.0 2.4 3 0 0 3 3 3 0 RAVE protein 1 C terminal Nop53 PF07767.11 OIR58819.1 - 8.1 5.7 33.4 5 6.4 0.8 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Kinesin PF00225.23 OIR58820.1 - 2e-102 342.6 1.4 2.8e-102 342.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OIR58820.1 - 5.9e-51 172.3 0.0 2e-50 170.6 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF3450 PF11932.8 OIR58820.1 - 0.039 13.3 16.5 0.011 15.0 5.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_16 PF13191.6 OIR58820.1 - 0.52 10.7 0.0 0.52 10.7 0.0 3.0 2 2 0 2 2 2 0 AAA ATPase domain Tropomyosin PF00261.20 OIR58820.1 - 1.9 7.8 38.8 2.2 7.6 35.3 2.9 1 1 0 1 1 1 0 Tropomyosin CENP-F_leu_zip PF10473.9 OIR58820.1 - 2.7 8.0 34.5 0.96 9.5 9.5 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4250 PF14056.6 OIR58820.1 - 2.8 8.0 4.6 56 3.8 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Thioredoxin PF00085.20 OIR58821.1 - 5.7e-06 26.3 0.1 0.057 13.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Flu_M1_C PF08289.11 OIR58822.1 - 0.016 15.4 0.8 0.6 10.3 0.1 2.3 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain DUF1664 PF07889.12 OIR58822.1 - 0.018 15.1 10.1 0.033 14.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V-SNARE_C PF12352.8 OIR58822.1 - 0.056 13.7 1.4 0.056 13.7 1.4 2.0 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus MscS_porin PF12795.7 OIR58822.1 - 0.12 11.9 18.1 0.02 14.4 4.3 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain SesA PF17107.5 OIR58822.1 - 0.28 11.4 9.6 0.16 12.2 2.2 2.3 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF5089 PF17002.5 OIR58822.1 - 0.44 10.4 30.3 0.04 13.8 24.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) TolA_bind_tri PF16331.5 OIR58822.1 - 1.5 9.0 11.1 0.085 12.9 1.0 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF745 PF05335.13 OIR58822.1 - 1.5 8.5 12.8 0.94 9.2 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 OIR58822.1 - 2.8 7.2 16.9 0.81 8.9 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HemX PF04375.14 OIR58822.1 - 2.9 7.1 15.3 0.52 9.5 5.6 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMEM192 PF14802.6 OIR58822.1 - 7.4 5.6 8.4 0.18 10.9 2.0 1.6 2 0 0 2 2 2 0 TMEM192 family Clat_adaptor_s PF01217.20 OIR58824.1 - 6.2e-15 55.4 1.9 8.7e-15 54.9 1.9 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 OIR58825.1 - 4.5e-60 203.3 0.0 6.3e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58825.1 - 2.2e-28 99.3 0.0 3.2e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR58825.1 - 8.9e-09 35.1 0.0 3.5e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OIR58825.1 - 4.9e-05 22.3 0.0 8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF2507 PF10702.9 OIR58825.1 - 0.016 15.1 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2507) APH PF01636.23 OIR58825.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3287 PF11690.8 OIR58826.1 - 0.44 10.3 5.4 0.41 10.4 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) FlxA PF14282.6 OIR58826.1 - 1.6 8.8 9.5 1.6 8.7 3.4 2.2 2 0 0 2 2 2 0 FlxA-like protein ACCA PF03255.14 OIR58826.1 - 2 8.3 10.1 1.2 8.9 2.4 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1664 PF07889.12 OIR58826.1 - 4.7 7.3 6.6 4.5 7.3 2.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 OIR58826.1 - 6.7 7.2 18.4 0.91 10.0 7.6 2.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) UQ_con PF00179.26 OIR58827.1 - 8.1e-49 164.9 0.0 9.9e-49 164.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RIO1 PF01163.22 OIR58828.1 - 2.6e-42 144.6 0.0 4.6e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 OIR58828.1 - 2.5e-19 69.3 0.0 5.7e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 OIR58828.1 - 6.5e-14 52.4 0.7 2e-06 27.9 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OIR58828.1 - 1.9e-10 40.4 0.0 1.1e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rrf2 PF02082.20 OIR58828.1 - 0.018 15.4 0.0 0.074 13.4 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator WaaY PF06176.11 OIR58828.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 OIR58828.1 - 0.19 11.1 0.0 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Na_Ca_ex PF01699.24 OIR58829.1 - 1.5e-19 70.5 41.7 1.5e-10 41.3 13.4 3.1 2 1 1 3 3 3 3 Sodium/calcium exchanger protein NAC PF01849.18 OIR58830.1 - 1.8e-09 37.4 0.2 2.7e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 NAC domain Peptidase_M24 PF00557.24 OIR58831.1 - 9e-37 126.8 0.0 1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 OIR58831.1 - 0.075 13.5 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain DUF1664 PF07889.12 OIR58832.1 - 0.0084 16.1 0.5 0.078 13.0 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) MerR-DNA-bind PF09278.11 OIR58832.1 - 0.059 13.9 0.2 21 5.8 0.0 2.7 2 0 0 2 2 2 0 MerR, DNA binding DUF2218 PF09981.9 OIR58832.1 - 0.1 13.0 0.1 2 8.8 0.0 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) WXG100 PF06013.12 OIR58832.1 - 0.13 12.5 0.3 28 5.0 0.0 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG YojJ PF10372.9 OIR58832.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus ABC_tran_CTD PF16326.5 OIR58832.1 - 0.14 12.4 0.9 12 6.2 0.0 3.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain SPC22 PF04573.12 OIR58833.1 - 4.1e-21 75.2 0.0 5e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit 7tm_3 PF00003.22 OIR58834.1 - 1.3e-37 129.8 22.4 2.3e-37 129.0 22.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 OIR58834.1 - 2.6e-25 89.3 0.0 3.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 OIR58834.1 - 1.1e-08 35.2 0.2 0.00011 22.0 0.0 2.8 3 0 0 3 3 3 2 Periplasmic binding protein Flavodoxin_1 PF00258.25 OIR58834.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin DUF981 PF06168.11 OIR58834.1 - 0.011 15.7 9.6 0.23 11.4 9.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF981) CrgA PF06781.12 OIR58834.1 - 0.12 12.4 2.0 0.42 10.7 0.1 2.6 2 1 1 3 3 3 0 Cell division protein CrgA HEAT_2 PF13646.6 OIR58835.1 - 7e-14 52.0 4.7 5.6e-09 36.3 0.0 5.2 4 2 1 5 5 5 2 HEAT repeats PC_rep PF01851.22 OIR58835.1 - 4.8e-09 36.2 12.2 0.11 13.0 0.1 7.9 7 0 0 7 7 7 3 Proteasome/cyclosome repeat HEAT PF02985.22 OIR58835.1 - 3.7e-05 23.6 0.8 2.3 8.7 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat RPN2_C PF18004.1 OIR58835.1 - 0.00012 22.1 0.5 0.00023 21.1 0.5 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_EZ PF13513.6 OIR58835.1 - 0.0024 18.3 2.3 1.8 9.2 0.2 4.0 4 0 0 4 4 4 2 HEAT-like repeat DUF4042 PF13251.6 OIR58835.1 - 0.14 11.9 0.0 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) RIG-I_C PF18119.1 OIR58836.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain YozD PF14162.6 OIR58836.1 - 0.11 12.9 0.2 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 YozD-like protein ThiF PF00899.21 OIR58837.1 - 1.5e-94 315.9 0.0 1.3e-70 237.5 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OIR58837.1 - 2.6e-61 207.7 0.0 3.4e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OIR58837.1 - 3.2e-27 94.5 0.4 7.2e-27 93.4 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OIR58837.1 - 1.5e-17 64.0 0.2 3.1e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OIR58837.1 - 0.00011 22.3 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle EpoR_lig-bind PF09067.10 OIR58838.1 - 0.64 10.3 5.8 0.21 11.8 1.6 2.2 1 1 0 2 2 2 0 Erythropoietin receptor, ligand binding COPI_C PF06957.11 OIR58839.1 - 1.7e-39 135.8 0.1 1.7e-39 135.8 0.1 2.2 2 0 0 2 2 2 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 OIR58839.1 - 3e-36 125.5 0.0 6.2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OIR58839.1 - 2.6e-28 97.7 12.6 1.7e-05 25.5 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58839.1 - 2.7e-06 27.6 2.2 0.69 10.3 0.0 5.5 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain MATalpha_HMGbox PF04769.12 OIR58840.1 - 0.038 13.3 3.7 0.08 12.2 0.0 2.4 2 1 0 3 3 3 0 Mating-type protein MAT alpha 1 HMG-box Proteasome PF00227.26 OIR58841.1 - 5.1e-45 153.3 0.0 7.2e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR58841.1 - 8.8e-14 50.9 0.4 1.6e-13 50.1 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pkinase PF00069.25 OIR58842.1 - 3e-41 141.5 0.0 4.8e-40 137.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58842.1 - 4.7e-21 75.2 0.0 2.4e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR58842.1 - 7.4e-08 32.1 0.0 9.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.29 OIR58843.1 - 1.1e-39 136.0 1.1 1.5e-39 135.5 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR58843.1 - 5.6e-30 104.0 0.0 7e-29 100.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58843.1 - 0.0005 20.1 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OIR58843.1 - 0.0073 16.7 0.2 0.053 13.9 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OIR58843.1 - 0.0091 15.7 4.3 0.018 14.7 2.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OIR58843.1 - 0.014 15.7 0.5 0.052 13.8 0.2 2.1 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 OIR58843.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Helicase AAA PF00004.29 OIR58843.1 - 0.027 14.9 0.0 0.12 12.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Terminase_6 PF03237.15 OIR58843.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Terminase-like family CRISPR_assoc PF08798.11 OIR58843.1 - 0.09 12.9 0.2 6.6 6.8 0.0 2.5 2 1 0 2 2 2 0 CRISPR associated protein tRNA_anti-codon PF01336.25 OIR58844.1 - 0.022 14.7 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Ras PF00071.22 OIR58845.1 - 1.1e-62 210.5 0.6 1.2e-62 210.3 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR58845.1 - 1.2e-34 119.1 0.1 2.1e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR58845.1 - 5.7e-16 58.5 0.1 7e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OIR58845.1 - 2.6e-06 27.0 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OIR58845.1 - 8.1e-06 25.5 0.2 1.6e-05 24.6 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OIR58845.1 - 3.1e-05 24.0 0.0 6.1e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OIR58845.1 - 3.3e-05 23.8 0.6 0.017 15.0 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OIR58845.1 - 5.7e-05 22.6 0.1 7.2e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OIR58845.1 - 0.0034 16.9 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 OIR58845.1 - 0.0047 16.7 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF3533 PF12051.8 OIR58845.1 - 0.015 14.2 0.2 0.018 14.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TniB PF05621.11 OIR58845.1 - 0.048 13.1 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Gpi1 PF05024.15 OIR58846.1 - 3.2e-30 105.6 4.9 5.1e-30 105.0 4.9 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) SNF2_N PF00176.23 OIR58847.1 - 1.7e-67 227.6 0.0 1.7e-67 227.6 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 OIR58847.1 - 1.8e-21 76.0 0.1 6e-21 74.3 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 OIR58847.1 - 1.1e-20 74.0 0.6 1.1e-19 70.9 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR58847.1 - 2e-11 44.2 0.8 2.6e-10 40.6 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 OIR58847.1 - 1.3e-05 25.4 15.3 2.5e-05 24.5 13.6 2.4 2 0 0 2 2 2 1 HSA RnaseA PF00074.20 OIR58847.1 - 0.28 11.6 2.3 0.6 10.6 2.3 1.4 1 0 0 1 1 1 0 Pancreatic ribonuclease Mac PF12464.8 OIR58847.1 - 0.6 10.4 2.9 3.4 8.0 0.1 3.5 3 0 0 3 3 3 0 Maltose acetyltransferase AAA_16 PF13191.6 OIR58847.1 - 1.3 9.4 5.9 9.2 6.6 0.8 3.7 3 1 0 3 3 3 0 AAA ATPase domain DBINO PF13892.6 OIR58847.1 - 1.8 8.9 20.3 2.1 8.7 18.1 2.5 1 1 0 1 1 1 0 DNA-binding domain DDHD PF02862.17 OIR58847.1 - 1.8 8.6 5.5 5.4 7.1 5.5 1.8 1 0 0 1 1 1 0 DDHD domain tRNA-synt_1b PF00579.25 OIR58848.1 - 1.2e-20 74.1 0.0 5.2e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) 6PGD PF00393.19 OIR58849.1 - 1.8e-98 329.5 0.0 2.3e-98 329.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OIR58849.1 - 2.3e-46 157.9 0.0 3.5e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OIR58849.1 - 0.0002 21.4 0.0 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OIR58849.1 - 0.0041 17.7 0.0 0.009 16.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 OIR58849.1 - 0.047 13.9 0.0 0.41 10.9 0.0 2.4 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase AAA PF00004.29 OIR58850.1 - 8.4e-46 155.7 0.0 4.5e-39 133.9 0.0 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OIR58850.1 - 1.5e-07 31.5 0.1 0.0027 17.7 0.1 3.8 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OIR58850.1 - 1.7e-07 31.8 0.1 0.0063 16.9 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 OIR58850.1 - 5.5e-07 29.8 0.0 0.0025 18.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 OIR58850.1 - 1.1e-06 28.3 1.2 0.0005 19.8 0.3 2.7 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 OIR58850.1 - 8.3e-05 22.4 0.0 0.0082 15.9 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OIR58850.1 - 0.00013 22.3 0.2 0.75 10.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 OIR58850.1 - 0.00016 21.0 0.0 0.0062 15.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 OIR58850.1 - 0.00037 21.0 0.0 0.3 11.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 OIR58850.1 - 0.00054 19.7 0.0 0.42 10.3 0.0 3.0 2 1 0 3 3 3 1 Sigma-54 interaction domain AAA_2 PF07724.14 OIR58850.1 - 0.00075 19.7 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 OIR58850.1 - 0.00092 19.2 0.3 0.38 10.7 0.0 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain NACHT PF05729.12 OIR58850.1 - 0.0018 18.2 1.7 5.3 6.9 0.1 3.7 3 1 0 4 4 4 0 NACHT domain ATPase PF06745.13 OIR58850.1 - 0.0021 17.4 0.0 0.071 12.4 0.0 2.6 3 0 0 3 3 3 1 KaiC Sigma54_activ_2 PF14532.6 OIR58850.1 - 0.0058 16.7 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 OIR58850.1 - 0.0065 16.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 OIR58850.1 - 0.0094 15.7 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OIR58850.1 - 0.0099 16.3 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_11 PF13086.6 OIR58850.1 - 0.014 15.2 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OIR58850.1 - 0.015 14.8 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 OIR58850.1 - 0.045 13.5 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 OIR58850.1 - 0.048 13.0 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OIR58850.1 - 0.055 13.1 0.0 0.91 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OIR58850.1 - 0.057 13.9 0.0 7.7 7.0 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 OIR58850.1 - 0.065 12.5 0.0 9.2 5.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 OIR58850.1 - 0.07 13.0 0.0 0.54 10.1 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase AAA_3 PF07726.11 OIR58850.1 - 0.079 12.8 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 OIR58850.1 - 0.099 12.8 0.5 7.2 6.7 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase AAA_30 PF13604.6 OIR58850.1 - 0.11 12.1 0.0 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OIR58850.1 - 0.12 11.8 0.0 3.7 6.9 0.0 2.8 3 0 0 3 3 3 0 Bacterial TniB protein AAA_24 PF13479.6 OIR58850.1 - 0.12 12.1 0.0 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.17 OIR58850.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Torsin PF06309.11 OIR58850.1 - 0.17 12.0 0.0 25 5.0 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_19 PF13245.6 OIR58850.1 - 0.18 12.1 0.0 36 4.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 OIR58851.1 - 9.6e-73 244.8 0.0 1.1e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR58851.1 - 5.4e-48 163.5 0.0 6.6e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR58851.1 - 4.4e-08 32.8 0.0 1.1e-06 28.2 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 OIR58851.1 - 0.00014 21.3 0.1 0.00022 20.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OIR58851.1 - 0.00024 20.0 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OIR58851.1 - 0.0017 18.0 0.9 0.071 12.7 0.0 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 OIR58851.1 - 0.0041 16.7 0.3 0.008 15.7 0.3 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 OIR58851.1 - 0.01 15.5 0.2 0.03 13.9 0.1 1.8 1 1 1 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 OIR58851.1 - 0.067 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Radical_SAM_C PF16199.5 OIR58851.1 - 0.086 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain DHHC PF01529.20 OIR58852.1 - 1.4e-36 125.5 7.7 1.9e-36 125.1 7.7 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Fcf1 PF04900.12 OIR58853.1 - 1.3e-30 105.7 0.2 1.9e-30 105.2 0.2 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OIR58853.1 - 1.8e-10 41.1 0.0 2.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 PIN like domain SPRY PF00622.28 OIR58854.1 - 1e-10 41.8 2.3 0.00032 20.8 0.0 2.2 2 0 0 2 2 2 2 SPRY domain DNA_pol_A_exo1 PF01612.20 OIR58855.1 - 1.9e-33 115.6 0.1 2.6e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease TRAPP PF04051.16 OIR58856.1 - 0.00016 21.4 0.0 0.00021 21.0 0.0 1.2 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Neur_chan_memb PF02932.16 OIR58857.1 - 0.37 10.8 1.0 0.73 9.9 1.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sod_Fe_C PF02777.18 OIR58858.1 - 3.3e-33 113.9 0.0 5.1e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OIR58858.1 - 1.2e-19 70.5 0.0 2.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ThiF PF00899.21 OIR58859.1 - 2.5e-58 197.3 0.1 3.5e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OIR58859.1 - 3.2e-07 30.8 0.0 6.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.16 OIR58859.1 - 0.097 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cpn60_TCP1 PF00118.24 OIR58860.1 - 1.5e-144 482.3 6.9 1.7e-144 482.1 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AbrB_C PF18277.1 OIR58860.1 - 0.047 13.3 0.1 12 5.6 0.0 2.6 2 0 0 2 2 2 0 AbrB C-terminal domain Ribosomal_S2 PF00318.20 OIR58861.1 - 1.4e-26 93.1 0.1 4.6e-13 48.9 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OIR58861.1 - 0.11 13.8 0.4 0.24 12.8 0.4 1.6 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Herpes_VP19C PF03327.14 OIR58861.1 - 0.16 11.4 0.0 0.68 9.3 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus capsid shell protein VP19C EKR PF10371.9 OIR58862.1 - 0.022 14.5 0.1 0.051 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function Fer2 PF00111.27 OIR58863.1 - 9.6e-14 51.1 0.8 1.2e-13 50.8 0.8 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 OIR58863.1 - 0.042 13.9 2.4 0.19 11.8 2.4 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF1364 PF07102.12 OIR58863.1 - 0.042 13.7 0.5 0.068 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) PARG_cat PF05028.14 OIR58865.1 - 0.0002 20.8 1.1 0.13 11.5 0.1 2.0 1 1 1 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) HSF_DNA-bind PF00447.17 OIR58867.1 - 1.4e-19 70.5 0.3 2.7e-19 69.5 0.1 1.6 2 0 0 2 2 2 1 HSF-type DNA-binding SKA2 PF16740.5 OIR58867.1 - 0.05 13.4 6.0 0.3 10.9 3.0 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Nsp1_C PF05064.13 OIR58867.1 - 0.06 13.1 5.0 0.11 12.3 5.0 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Ribosomal_S13_N PF08069.12 OIR58868.1 - 1.3e-24 85.9 0.2 3.2e-24 84.7 0.1 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OIR58868.1 - 2.9e-11 43.4 0.6 4.8e-11 42.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 VCBS PF13517.6 OIR58870.1 - 0.004 17.7 0.1 0.16 12.6 0.0 3.3 3 1 1 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TFIIE_alpha PF02002.17 OIR58871.1 - 2e-14 53.3 3.0 8.1e-14 51.4 1.9 2.1 2 0 0 2 2 2 1 TFIIE alpha subunit zf-C3HC PF07967.13 OIR58871.1 - 0.075 13.1 0.6 0.15 12.1 0.6 1.5 1 0 0 1 1 1 0 C3HC zinc finger-like HTH_27 PF13463.6 OIR58871.1 - 0.087 13.3 1.0 0.98 10.0 0.4 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain zf-C2H2_12 PF18658.1 OIR58871.1 - 0.099 12.2 1.0 3 7.5 0.0 2.5 1 1 1 2 2 2 0 Zinc-finger C2H2-type CaiF_GrlA PF07180.11 OIR58871.1 - 0.15 12.1 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator Ta0938 PF11494.8 OIR58871.1 - 0.25 11.6 3.1 0.13 12.5 0.5 1.9 2 0 0 2 2 2 0 Ta0938 Kinesin PF00225.23 OIR58872.1 - 1.7e-105 352.7 0.1 1.7e-105 352.7 0.1 2.4 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OIR58872.1 - 4.2e-23 81.9 0.0 4.2e-23 81.9 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding DUF507 PF04368.13 OIR58872.1 - 0.05 13.5 5.0 0.12 12.3 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF507) Filament PF00038.21 OIR58872.1 - 0.13 11.8 19.4 1.3 8.5 0.3 2.8 2 1 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 OIR58872.1 - 2.7 7.3 12.8 6.3 6.0 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) T3SSipB PF16535.5 OIR58872.1 - 4.8 7.6 9.2 1.4 9.4 5.1 2.2 2 1 0 2 2 2 0 Type III cell invasion protein SipB Peptidase_M48 PF01435.18 OIR58873.1 - 4.2e-18 65.8 0.1 7.3e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 EIID-AGA PF03613.14 OIR58873.1 - 0.066 12.4 2.7 1.7 7.7 0.3 2.5 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component MFS_1_like PF12832.7 OIR58874.1 - 5e-33 114.5 13.2 9.2e-33 113.6 13.2 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OIR58874.1 - 1e-11 44.4 12.5 2.3e-10 40.0 3.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CitMHS PF03600.16 OIR58874.1 - 0.012 14.8 0.0 0.32 10.2 0.0 2.4 2 1 0 2 2 2 0 Citrate transporter DUF2615 PF11027.8 OIR58874.1 - 0.016 15.3 0.1 0.7 10.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) Polysacc_deac_1 PF01522.21 OIR58875.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide deacetylase CENP-B_dimeris PF09026.10 OIR58875.1 - 0.16 12.4 4.7 0.47 10.9 4.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MIG-14_Wnt-bd PF06664.12 OIR58877.1 - 0.00012 21.5 0.4 0.00014 21.2 0.4 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Proteasome PF00227.26 OIR58878.1 - 3e-57 193.2 0.0 3.7e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OIR58878.1 - 4.1e-07 29.5 0.1 7.3e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WD40 PF00400.32 OIR58879.1 - 1e-18 67.3 7.6 0.054 14.4 0.0 8.8 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58879.1 - 1.8e-12 47.4 0.0 0.12 12.7 0.0 7.8 5 2 4 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OIR58879.1 - 0.00028 20.0 0.1 0.58 9.1 0.0 3.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OIR58879.1 - 0.021 14.8 3.8 0.75 9.8 0.0 4.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 OIR58879.1 - 0.021 14.4 0.6 5.1 6.6 0.1 3.5 3 2 1 4 4 4 0 PQQ-like domain Utp12 PF04003.12 OIR58879.1 - 0.022 15.1 0.7 0.038 14.3 0.7 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Coatomer_WDAD PF04053.14 OIR58879.1 - 0.031 13.3 0.0 2.7 6.9 0.0 2.8 2 1 0 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 OIR58879.1 - 0.074 11.6 0.0 6.4 5.2 0.0 3.0 4 0 0 4 4 4 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 OIR58879.1 - 9 6.9 9.3 12 6.5 0.2 4.9 5 1 1 6 6 6 0 PQQ-like domain DUF2428 PF10350.9 OIR58880.1 - 8.1e-28 97.5 0.0 1.8e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) Nitrophorin PF02087.15 OIR58881.1 - 0.022 14.8 2.8 0.026 14.5 2.8 1.1 1 0 0 1 1 1 0 Nitrophorin CK_II_beta PF01214.18 OIR58882.1 - 9.3e-63 211.3 0.0 1.1e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit tRNA-synt_2 PF00152.20 OIR58883.1 - 4.5e-90 301.9 0.1 7.6e-90 301.2 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OIR58883.1 - 1.6e-10 40.8 0.2 3.4e-10 39.8 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LPD13 PF18825.1 OIR58883.1 - 0.041 13.7 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 DUF4539 PF15072.6 OIR58883.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Clat_adaptor_s PF01217.20 OIR58884.1 - 1.6e-05 24.8 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Thioredoxin PF00085.20 OIR58885.1 - 6.5e-27 93.5 0.1 7.3e-27 93.4 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OIR58885.1 - 3.8e-07 30.5 0.2 7.2e-06 26.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OIR58885.1 - 0.00011 22.5 0.0 0.00022 21.5 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OIR58885.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OIR58885.1 - 0.00031 20.2 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 OIR58885.1 - 0.0005 19.9 0.0 0.00058 19.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 OIR58885.1 - 0.021 14.6 0.3 0.044 13.5 0.3 1.5 1 1 0 1 1 1 0 Redoxin Phosducin PF02114.16 OIR58885.1 - 0.098 11.6 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin Ribosomal_L34e PF01199.18 OIR58886.1 - 3.8e-34 116.9 5.6 4.1e-34 116.8 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Nop16 PF09420.10 OIR58888.1 - 1.8e-08 34.7 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Thioredoxin PF00085.20 OIR58889.1 - 4.3e-16 58.8 0.1 6.2e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 OIR58889.1 - 4.7e-07 30.2 0.1 0.0033 17.9 0.0 2.5 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 OIR58889.1 - 9.8e-07 28.7 0.0 0.008 16.1 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 OIR58889.1 - 2.4e-06 27.6 0.0 0.029 14.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 OIR58889.1 - 0.00012 22.1 0.1 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_8 PF13905.6 OIR58889.1 - 0.00015 22.0 0.7 3.8 7.9 0.1 3.9 2 2 1 3 3 3 2 Thioredoxin-like Glutaredoxin PF00462.24 OIR58889.1 - 0.0028 17.8 0.1 0.12 12.6 0.0 2.7 2 1 0 2 2 2 1 Glutaredoxin OST3_OST6 PF04756.13 OIR58889.1 - 0.0096 15.3 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 OIR58889.1 - 0.063 13.0 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Redoxin DUF953 PF06110.11 OIR58889.1 - 0.24 11.0 1.5 1 9.0 0.1 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) DER1 PF04511.15 OIR58890.1 - 1.4e-46 158.8 10.2 1.7e-46 158.6 10.2 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_L36e PF01158.18 OIR58892.1 - 2.2e-28 98.3 7.3 2.8e-28 98.0 7.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 OIR58892.1 - 0.0091 15.6 0.1 0.012 15.2 0.1 1.3 1 1 0 1 1 1 1 Four helix bundle sensory module for signal transduction LSM PF01423.22 OIR58893.1 - 7.3e-18 64.0 0.0 8.1e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OIR58893.1 - 0.032 14.4 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Mre11_DNA_bind PF04152.14 OIR58894.1 - 1.7e-15 57.8 0.0 3.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OIR58894.1 - 2.2e-13 51.2 0.9 3.9e-13 50.4 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OIR58894.1 - 8.3e-08 32.6 0.0 7e-07 29.6 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L29 PF00831.23 OIR58895.1 - 1.8e-15 56.6 0.5 1.8e-15 56.6 0.5 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein PGC7_Stella PF15549.6 OIR58895.1 - 0.04 13.9 2.7 0.05 13.6 2.7 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain ThiD2 PF17792.1 OIR58895.1 - 0.075 13.5 5.4 0.11 12.9 5.4 1.4 1 1 0 1 1 1 0 ThiD2 family RtcB PF01139.17 OIR58895.1 - 2.8 7.0 5.8 0.11 11.7 0.4 1.4 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB Mnd1 PF03962.15 OIR58898.1 - 3.3e-20 72.1 0.0 5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 OIR58898.1 - 6.6e-11 42.1 0.0 1.5e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Pre-PUA PF17832.1 OIR58898.1 - 0.018 15.7 0.3 0.31 11.7 0.1 2.3 2 0 0 2 2 2 0 Pre-PUA-like domain DivIC PF04977.15 OIR58898.1 - 0.049 13.4 0.6 0.69 9.7 0.0 2.5 3 0 0 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 OIR58898.1 - 2.3 8.5 6.1 5.4 7.4 2.3 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Rer1 PF03248.13 OIR58899.1 - 2.5e-57 193.4 8.8 2.8e-57 193.2 8.8 1.0 1 0 0 1 1 1 1 Rer1 family Peptidase_M56 PF05569.11 OIR58899.1 - 0.078 12.2 0.3 0.095 11.9 0.3 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4131 PF13567.6 OIR58899.1 - 0.15 11.7 6.1 0.28 10.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Lyase_1 PF00206.20 OIR58900.1 - 1 8.7 4.5 1.4 8.3 4.5 1.1 1 0 0 1 1 1 0 Lyase Peptidase_U49 PF10463.9 OIR58900.1 - 2.4 7.9 9.9 2.4 7.9 7.2 2.2 1 1 0 1 1 1 0 Peptidase U49 Spore_YhaL PF14147.6 OIR58900.1 - 5.6 6.7 5.9 4.2 7.1 1.6 3.1 2 1 0 2 2 2 0 Sporulation protein YhaL Adaptin_N PF01602.20 OIR58901.1 - 1.8e-28 99.4 7.1 1.1e-26 93.6 7.1 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 OIR58901.1 - 6.4e-13 48.8 0.0 1.5e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 OIR58901.1 - 3.3e-12 46.5 0.0 1e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 OIR58901.1 - 7.5e-06 26.2 0.1 0.027 14.8 0.0 3.0 2 0 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 OIR58901.1 - 0.00011 22.3 1.5 0.0034 17.4 0.1 3.0 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OIR58901.1 - 0.014 15.6 0.4 0.89 10.0 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Nipped-B_C PF12830.7 OIR58901.1 - 0.066 13.1 0.0 0.3 11.0 0.0 2.1 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus RhoGAP PF00620.27 OIR58901.1 - 0.18 11.6 2.1 0.96 9.3 0.2 2.7 3 0 0 3 3 3 0 RhoGAP domain Ribosomal_L28e PF01778.17 OIR58902.1 - 2.2e-20 73.5 0.0 4.1e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 OIR58902.1 - 3.6e-08 33.9 6.3 7.1e-08 33.0 6.3 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region CLTH PF10607.9 OIR58903.1 - 3.1e-05 23.9 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_5 PF14634.6 OIR58903.1 - 0.013 15.5 0.3 0.043 13.8 0.3 2.0 1 0 0 1 1 1 0 zinc-RING finger domain SPAM PF02090.15 OIR58903.1 - 0.017 15.0 0.2 0.035 13.9 0.2 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein zf-RING_UBOX PF13445.6 OIR58903.1 - 0.018 15.1 0.7 0.018 15.1 0.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Rtf2 PF04641.12 OIR58903.1 - 0.037 13.4 0.3 0.063 12.6 0.3 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger V_ATPase_I PF01496.19 OIR58903.1 - 0.19 9.6 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DnaJ PF00226.31 OIR58905.1 - 2.2e-19 69.3 0.0 3.5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 OIR58906.1 - 8.2e-32 108.7 21.0 1.5e-09 38.3 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58906.1 - 8.4e-09 35.6 2.7 0.081 13.2 0.0 4.4 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 OIR58906.1 - 0.00011 21.7 0.1 0.003 16.9 0.0 2.7 3 1 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 OIR58906.1 - 0.00035 19.6 3.1 0.03 13.3 0.3 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 OIR58906.1 - 0.0013 17.9 1.9 0.58 9.2 0.0 3.4 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) PD40 PF07676.12 OIR58906.1 - 0.0026 17.6 3.1 7.9 6.6 0.0 4.9 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OIR58906.1 - 0.014 14.1 4.9 0.043 12.5 2.1 3.2 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Peptidase_S9_N PF02897.15 OIR58906.1 - 0.14 10.9 0.1 1.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Metallophos PF00149.28 OIR58907.1 - 4.2e-29 102.5 0.0 6.7e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 OIR58907.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) CE2_N PF17996.1 OIR58908.1 - 0.031 14.2 1.5 0.062 13.3 1.5 1.4 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal COX15-CtaA PF02628.15 OIR58908.1 - 0.055 12.5 0.8 0.087 11.9 0.8 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein DUF1764 PF08576.10 OIR58909.1 - 9.8e-10 39.2 11.4 3.3e-09 37.5 11.4 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Fcf2 PF08698.11 OIR58910.1 - 0.0083 16.5 0.6 0.017 15.5 0.5 1.5 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing mRNA_triPase PF02940.15 OIR58911.1 - 9.4e-38 130.1 1.1 1.1e-37 129.9 1.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF2277 PF10041.9 OIR58912.1 - 0.014 15.7 0.0 2.3 8.6 0.0 4.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) HEAT PF02985.22 OIR58912.1 - 0.099 12.9 4.1 3.7 8.1 0.2 4.4 3 0 0 3 3 3 0 HEAT repeat MCM PF00493.23 OIR58913.1 - 1.1e-97 325.6 0.0 1.5e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OIR58913.1 - 1.9e-36 124.7 0.1 3.7e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OIR58913.1 - 2.3e-25 88.8 0.3 7e-23 80.9 0.0 2.7 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OIR58913.1 - 1.3e-08 35.4 0.0 3.6e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OIR58913.1 - 5.4e-08 32.5 0.1 2.8e-07 30.2 0.0 2.2 2 2 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OIR58913.1 - 0.00013 22.0 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OIR58913.1 - 0.00084 19.2 0.0 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DHFR_1 PF00186.19 OIR58914.1 - 1.1e-29 103.2 0.0 3.5e-23 82.1 0.0 2.1 1 1 1 2 2 2 2 Dihydrofolate reductase Thioredoxin PF00085.20 OIR58915.1 - 1.9e-06 27.8 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OIR58915.1 - 0.0053 16.9 0.0 0.0094 16.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 OIR58915.1 - 0.0094 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family RRM_1 PF00076.22 OIR58916.1 - 1e-79 262.3 0.4 1.6e-20 72.7 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OIR58916.1 - 2e-07 31.0 0.0 0.24 11.6 0.0 4.6 4 2 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 OIR58916.1 - 0.00017 21.6 0.8 1.6 8.9 0.1 3.7 3 1 1 4 4 4 2 RNA binding motif TC1 PF15063.6 OIR58916.1 - 0.00054 19.8 0.0 1.8 8.5 0.0 4.0 4 0 0 4 4 4 2 Thyroid cancer protein 1 Nup35_RRM_2 PF14605.6 OIR58916.1 - 0.0024 17.8 0.8 17 5.5 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 OIR58916.1 - 0.01 15.9 0.0 1.2 9.2 0.0 3.7 3 1 1 4 4 4 0 Limkain b1 DUF3347 PF11827.8 OIR58916.1 - 0.042 14.0 0.0 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) zf-RING_2 PF13639.6 OIR58917.1 - 2.2e-13 50.3 7.4 4.7e-13 49.3 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OIR58917.1 - 2.3e-12 46.4 4.0 2.3e-12 46.4 4.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OIR58917.1 - 1.1e-09 38.0 5.5 2e-09 37.1 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR58917.1 - 9.8e-09 35.0 4.2 2.3e-08 33.7 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OIR58917.1 - 1.4e-07 31.4 2.9 2.2e-06 27.6 1.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OIR58917.1 - 6.9e-07 29.1 3.2 1.1e-06 28.5 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OIR58917.1 - 2e-06 28.0 10.2 8.7e-06 25.9 10.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OIR58917.1 - 5e-05 23.1 2.6 8.1e-05 22.4 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OIR58917.1 - 0.00048 20.1 4.1 0.0014 18.6 4.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OIR58917.1 - 0.00064 19.5 3.8 0.0015 18.3 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OIR58917.1 - 0.019 15.1 1.7 0.057 13.6 1.7 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_trans_2_3 PF13632.6 OIR58917.1 - 0.07 13.0 0.8 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family group 2 SGBP_B_XBD PF18329.1 OIR58917.1 - 0.14 12.1 0.4 0.21 11.5 0.4 1.2 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain PHD PF00628.29 OIR58917.1 - 0.23 11.4 7.0 0.069 13.1 4.0 1.7 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 OIR58917.1 - 0.29 11.0 4.4 0.51 10.2 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 OIR58917.1 - 0.39 10.9 6.4 0.96 9.6 6.4 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 OIR58917.1 - 1.1 9.5 4.4 5.5 7.2 4.4 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 OIR58917.1 - 2.9 7.6 6.0 6.1 6.5 6.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2046 PF09755.9 OIR58918.1 - 3.1e-13 49.6 32.7 8.6e-13 48.2 32.7 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) TrwC PF08751.11 OIR58918.1 - 5.6 6.4 9.5 0.13 11.8 2.6 1.6 2 0 0 2 2 2 0 TrwC relaxase DUF4407 PF14362.6 OIR58918.1 - 6 6.1 7.5 14 4.9 7.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IFP_35_N PF07334.13 OIR58918.1 - 7.5 6.7 14.3 2.6 8.2 0.3 3.3 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RNase_P_p30 PF01876.16 OIR58919.1 - 3.1e-35 121.6 0.0 3.8e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit p30 DUF2883 PF11097.8 OIR58919.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) GPI-anchored PF10342.9 OIR58920.1 - 3.1e-05 24.6 0.2 0.017 15.9 0.0 2.2 2 0 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5125 PF17163.4 OIR58921.1 - 0.0023 18.2 1.1 0.0032 17.7 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5125) Peptidase_C24 PF03510.14 OIR58921.1 - 1.3 9.5 6.7 0.4 11.2 1.9 2.0 1 1 1 2 2 2 0 2C endopeptidase (C24) cysteine protease family V-SNARE_C PF12352.8 OIR58922.1 - 0.00027 21.2 0.4 0.00042 20.5 0.4 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus FixQ PF05545.11 OIR58922.1 - 0.047 13.7 0.6 0.07 13.1 0.6 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ UTP25 PF06862.12 OIR58923.1 - 3.8e-74 250.2 1.1 2.3e-72 244.3 1.1 2.0 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 STATa_Ig PF18214.1 OIR58924.1 - 0.096 12.7 0.9 0.8 9.7 0.1 2.2 2 0 0 2 2 2 0 STATa Immunoglobulin-like domain RUN PF02759.19 OIR58924.1 - 0.15 12.0 0.6 0.29 11.1 0.6 1.7 1 1 0 1 1 1 0 RUN domain Rad10 PF03834.14 OIR58924.1 - 0.26 11.3 3.0 0.15 12.1 0.4 2.0 2 1 0 2 2 2 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) SH3_9 PF14604.6 OIR58925.1 - 1.1e-13 50.8 0.1 2.1e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OIR58925.1 - 2.8e-10 39.7 0.0 4.8e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OIR58925.1 - 6.2e-09 35.4 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 OIR58925.1 - 0.00035 20.8 0.1 0.00069 19.8 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_4 PF06347.13 OIR58925.1 - 0.015 15.1 0.1 0.036 13.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4778 PF16008.5 OIR58925.1 - 0.021 14.9 8.9 0.029 14.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Fzo_mitofusin PF04799.13 OIR58925.1 - 0.1 12.2 5.5 0.88 9.1 2.0 2.4 2 0 0 2 2 2 0 fzo-like conserved region HAUS-augmin3 PF14932.6 OIR58925.1 - 0.49 9.9 11.3 0.57 9.7 10.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 PhnA_Zn_Ribbon PF08274.12 OIR58927.1 - 0.014 15.3 0.3 0.014 15.3 0.3 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon TnpV PF14198.6 OIR58927.1 - 0.18 11.8 3.5 1.7 8.6 0.2 2.8 2 1 1 3 3 3 0 Transposon-encoded protein TnpV Zn_Tnp_IS1 PF03811.13 OIR58927.1 - 1.6 8.5 4.2 0.45 10.3 0.4 2.0 2 0 0 2 2 2 0 InsA N-terminal domain CytochromB561_N PF09786.9 OIR58928.1 - 1.8e-07 30.5 0.0 1.9e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome B561, N terminal DUF3809 PF12723.7 OIR58928.1 - 0.019 15.3 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) Dus PF01207.17 OIR58930.1 - 4.9e-46 157.2 0.0 6e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 OIR58930.1 - 0.0017 17.9 0.1 0.0057 16.1 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein zf-C3HC4_3 PF13920.6 OIR58932.1 - 7.7e-05 22.5 7.8 7.7e-05 22.5 7.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR58932.1 - 0.00023 21.2 6.1 0.00097 19.2 4.8 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger GcrA PF07750.11 OIR58933.1 - 0.14 12.5 0.2 28 5.1 0.0 2.9 2 1 0 3 3 3 0 GcrA cell cycle regulator zf-C3HC4_3 PF13920.6 OIR58934.1 - 2.1e-05 24.3 6.9 4e-05 23.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR58934.1 - 0.00094 19.2 4.8 0.002 18.2 4.8 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Imm58 PF15581.6 OIR58934.1 - 0.022 14.9 6.5 1.9 8.6 0.1 5.1 4 2 2 6 6 6 0 Immunity protein 58 DUF2436 PF10365.9 OIR58934.1 - 0.072 12.8 0.0 8.1 6.2 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2436) Terminase_5 PF06056.12 OIR58934.1 - 0.13 12.2 10.2 37 4.3 0.0 6.4 7 0 0 7 7 7 0 Putative ATPase subunit of terminase (gpP-like) NOB1_Zn_bind PF08772.11 OIR58934.1 - 0.21 11.8 2.1 0.61 10.3 2.1 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TnpV PF14198.6 OIR58934.1 - 0.23 11.5 29.9 7 6.7 0.1 8.3 4 2 3 8 8 8 0 Transposon-encoded protein TnpV FYVE_2 PF02318.16 OIR58934.1 - 0.47 10.7 4.5 2.2 8.5 4.5 2.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.6 OIR58934.1 - 0.59 10.0 8.8 1.7 8.5 8.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain HypA PF01155.19 OIR58934.1 - 2.3 8.3 7.2 54 3.8 5.1 3.2 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FH2 PF02181.23 OIR58935.1 - 3.7e-36 125.0 3.7 7.8e-36 124.0 3.7 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 OIR58935.1 - 1.2e-13 51.1 0.3 2.9e-13 49.9 0.3 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 OIR58935.1 - 1.1e-07 31.7 0.4 2.2e-06 27.4 0.2 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Mito_fiss_reg PF05308.11 OIR58935.1 - 0.034 14.2 4.0 0.079 13.0 4.0 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Vac14_Fig4_bd PF11916.8 OIR58935.1 - 0.093 12.4 1.7 15 5.2 0.1 3.4 3 0 0 3 3 3 0 Vacuolar protein 14 C-terminal Fig4p binding Caskin-Pro-rich PF16907.5 OIR58935.1 - 0.28 11.7 3.2 0.71 10.4 3.2 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins ATG16 PF08614.11 OIR58935.1 - 2 8.6 9.6 0.72 10.1 3.4 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ribosomal_S26e PF01283.19 OIR58936.1 - 2.4e-46 156.6 11.8 2.8e-46 156.4 11.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Mu-like_Com PF10122.9 OIR58936.1 - 0.0031 16.9 0.1 0.0066 15.9 0.1 1.5 1 0 0 1 1 1 1 Mu-like prophage protein Com SRP19 PF01922.17 OIR58936.1 - 0.0045 17.9 0.3 0.0064 17.4 0.3 1.2 1 0 0 1 1 1 1 SRP19 protein AAA_18 PF13238.6 OIR58937.1 - 1.1e-27 97.2 0.1 1.4e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OIR58937.1 - 1.6e-08 35.1 0.0 3.6e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OIR58937.1 - 2.2e-06 28.1 0.1 5.5e-06 26.8 0.1 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 OIR58937.1 - 7.9e-06 25.9 1.1 0.0018 18.2 0.1 2.1 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_33 PF13671.6 OIR58937.1 - 1.3e-05 25.4 0.0 0.0018 18.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OIR58937.1 - 4.6e-05 23.4 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ADK PF00406.22 OIR58937.1 - 0.00011 22.3 0.1 0.0041 17.2 0.1 2.3 1 1 0 1 1 1 1 Adenylate kinase AAA_28 PF13521.6 OIR58937.1 - 0.00064 20.0 1.7 0.0014 18.9 0.5 2.0 1 1 1 2 2 2 1 AAA domain SKI PF01202.22 OIR58937.1 - 0.00079 19.6 0.5 0.0026 17.9 0.5 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_7 PF12775.7 OIR58937.1 - 0.0011 18.5 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 OIR58937.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 OIR58937.1 - 0.0021 18.2 0.3 0.048 13.8 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.15 OIR58937.1 - 0.0023 17.9 0.3 0.0066 16.4 0.1 1.9 2 1 1 3 3 3 1 NTPase AAA_24 PF13479.6 OIR58937.1 - 0.0025 17.6 0.3 0.008 15.9 0.1 1.8 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 OIR58937.1 - 0.0028 18.0 0.2 0.013 15.9 0.1 2.1 1 1 1 2 2 2 1 RNA helicase TsaE PF02367.17 OIR58937.1 - 0.0033 17.4 0.0 0.0067 16.4 0.0 1.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE 6PF2K PF01591.18 OIR58937.1 - 0.0035 16.7 0.1 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_16 PF13191.6 OIR58937.1 - 0.0042 17.5 0.0 0.0069 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 OIR58937.1 - 0.0047 16.4 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.6 OIR58937.1 - 0.0068 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 OIR58937.1 - 0.0086 15.9 0.1 0.16 11.8 0.1 2.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 OIR58937.1 - 0.012 15.9 0.1 0.016 15.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OIR58937.1 - 0.019 14.2 0.2 0.037 13.2 0.1 1.6 2 1 0 2 2 2 0 NB-ARC domain Thymidylate_kin PF02223.17 OIR58937.1 - 0.031 13.9 0.3 2.2 7.9 0.0 2.4 1 1 0 2 2 2 0 Thymidylate kinase PRK PF00485.18 OIR58937.1 - 0.036 13.8 0.4 0.42 10.3 0.1 2.1 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family Parvo_NS1 PF01057.17 OIR58937.1 - 0.043 12.9 0.1 0.087 11.9 0.1 1.8 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 OIR58937.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain GvpD PF07088.11 OIR58937.1 - 0.046 12.3 0.0 0.051 12.2 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_30 PF13604.6 OIR58937.1 - 0.047 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OIR58937.1 - 0.048 12.9 0.0 0.097 11.9 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 OIR58937.1 - 0.05 12.8 0.1 0.1 11.8 0.1 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain NOG1_N PF17835.1 OIR58937.1 - 0.075 13.0 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 NOG1 N-terminal helical domain RuvB_N PF05496.12 OIR58937.1 - 0.078 12.7 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 OIR58937.1 - 0.098 11.9 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 OIR58937.1 - 0.098 12.7 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OIR58937.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ploopntkinase3 PF18751.1 OIR58937.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 OIR58937.1 - 0.26 11.8 0.4 0.43 11.1 0.4 1.8 1 1 0 1 1 1 0 ABC transporter HEAT PF02985.22 OIR58938.1 - 6.5e-13 47.7 7.2 0.19 12.1 0.1 7.9 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 OIR58938.1 - 5.5e-09 36.3 2.5 0.17 12.3 0.0 5.3 3 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 OIR58938.1 - 5.3e-07 30.0 8.6 0.01 16.4 0.0 5.9 6 1 0 6 6 6 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OIR58938.1 - 0.00051 20.6 0.0 5.4 7.7 0.0 5.1 3 2 2 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OIR58938.1 - 0.0025 17.9 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 OIR58938.1 - 0.031 14.2 0.1 0.4 10.6 0.0 2.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain Adaptin_N PF01602.20 OIR58938.1 - 0.034 12.7 0.0 4 5.9 0.0 2.5 2 0 0 2 2 2 0 Adaptin N terminal region DUF1258 PF06869.12 OIR58938.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Tti2 PF10521.9 OIR58938.1 - 0.082 12.4 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Tti2 family DUF1416 PF07210.12 OIR58938.1 - 0.11 12.3 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) zf-C3HC4_3 PF13920.6 OIR58939.1 - 3.9e-05 23.4 6.1 8.4e-05 22.4 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 OIR58939.1 - 0.027 14.6 4.1 0.069 13.3 4.1 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Di19 PF05605.12 OIR58939.1 - 0.16 12.3 5.2 1 9.7 0.1 2.9 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding ANAPC15 PF15243.6 OIR58939.1 - 1.6 9.2 9.2 31 5.1 0.1 4.5 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 15 zf-RING_5 PF14634.6 OIR58939.1 - 1.6 8.8 6.7 3.7 7.6 6.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 OIR58939.1 - 1.8 8.4 7.3 67 3.4 7.3 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 OIR58939.1 - 3.6 7.7 8.6 18 5.5 7.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 OIR58939.1 - 5 7.4 6.8 19 5.5 0.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ras PF00071.22 OIR58940.1 - 1.1e-48 164.9 0.0 1.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR58940.1 - 1.3e-29 102.9 0.0 2.8e-29 101.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR58940.1 - 2.2e-10 40.2 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 OIR58940.1 - 0.00032 21.0 0.2 0.0062 16.9 0.2 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 OIR58940.1 - 0.001 18.5 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OIR58940.1 - 0.0035 17.4 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 OIR58940.1 - 0.0049 16.1 1.2 1.7 7.7 0.1 2.4 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 OIR58940.1 - 0.016 14.7 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 OIR58940.1 - 0.021 14.7 0.0 7.3 6.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 OIR58940.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 OIR58940.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OIR58940.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 OIR58940.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 OIR58940.1 - 0.11 12.7 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain ArgoMid PF16487.5 OIR58940.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Mid domain of argonaute TsaE PF02367.17 OIR58940.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE COG4 PF08318.12 OIR58941.1 - 9.9e-14 51.1 0.8 2.9e-13 49.6 0.8 2.0 1 1 0 1 1 1 1 COG4 transport protein Reg_prop PF07494.11 OIR58942.1 - 8.7e-05 22.3 3.2 1.8e+02 2.9 0.0 8.4 11 0 0 11 11 11 0 Two component regulator propeller TnpV PF14198.6 OIR58942.1 - 0.081 12.9 30.2 1.5 8.9 0.6 9.3 5 2 5 10 10 10 0 Transposon-encoded protein TnpV EIF_2_alpha PF07541.12 OIR58942.1 - 0.13 12.4 0.4 21 5.2 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 2 alpha subunit Lectin_C PF00059.21 OIR58942.1 - 1.5 9.5 5.6 1.8e+02 2.9 0.0 5.9 8 1 1 9 9 9 0 Lectin C-type domain GTP_EFTU PF00009.27 OIR58943.1 - 1.4e-40 139.0 0.0 1.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OIR58943.1 - 2.7e-18 66.3 0.0 6.6e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OIR58943.1 - 3.2e-08 33.9 1.1 8.8e-08 32.4 1.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OIR58943.1 - 0.0014 18.7 0.1 0.0079 16.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OIR58943.1 - 0.032 13.5 0.1 4.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU_D4 PF14578.6 OIR58943.1 - 0.089 12.7 1.0 0.29 11.1 1.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 DUF4968 PF16338.5 OIR58943.1 - 0.11 12.8 0.3 0.31 11.4 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) FeoB_N PF02421.18 OIR58943.1 - 0.16 11.5 0.7 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B zf-CSL PF05207.13 OIR58944.1 - 3.3e-17 61.9 0.4 4e-17 61.7 0.4 1.1 1 0 0 1 1 1 1 CSL zinc finger GTP_EFTU_D2 PF03144.25 OIR58945.1 - 0.0029 18.0 0.2 0.055 13.9 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TGT PF01702.18 OIR58945.1 - 0.0067 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Epimerase PF01370.21 OIR58946.1 - 1.8e-48 165.1 0.0 2.3e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OIR58946.1 - 2.5e-14 53.4 1.5 2e-13 50.5 0.1 1.9 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OIR58946.1 - 7.8e-08 31.8 0.0 3.3e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OIR58946.1 - 0.00063 19.0 1.2 0.05 12.7 0.0 2.5 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NmrA PF05368.13 OIR58946.1 - 0.0012 18.4 1.2 0.86 9.1 0.0 2.9 2 1 0 2 2 2 2 NmrA-like family Fungal_trans_2 PF11951.8 OIR58947.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain BAF250_C PF12031.8 OIR58949.1 - 0.078 12.3 0.1 0.44 9.8 0.0 1.9 1 1 1 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa Bromo_MP PF01573.16 OIR58950.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 Bromovirus movement protein SOAR PF16533.5 OIR58950.1 - 0.13 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 STIM1 Orai1-activating region BAF250_C PF12031.8 OIR58951.1 - 1.7e-06 27.6 0.8 0.47 9.7 0.0 4.4 3 1 1 4 4 4 3 SWI/SNF-like complex subunit BAF250/Osa Reg_prop PF07494.11 OIR58951.1 - 0.00011 22.0 0.6 12 6.5 0.0 5.9 7 0 0 7 7 7 1 Two component regulator propeller PhnA_Zn_Ribbon PF08274.12 OIR58951.1 - 0.029 14.3 0.2 0.029 14.3 0.2 1.9 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1 PF03811.13 OIR58951.1 - 0.064 13.0 0.2 0.064 13.0 0.2 1.9 2 0 0 2 2 2 0 InsA N-terminal domain zf-C3HC4_3 PF13920.6 OIR58951.1 - 0.069 13.0 6.6 0.14 12.1 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SPATA6 PF14909.6 OIR58951.1 - 0.1 12.8 0.2 4.9 7.3 0.0 3.5 4 1 0 4 4 4 0 Spermatogenesis-assoc protein 6 TnpV PF14198.6 OIR58951.1 - 0.16 12.0 18.2 0.6 10.1 0.4 6.0 4 2 3 7 7 7 0 Transposon-encoded protein TnpV Nucleic_acid_bd PF13820.6 OIR58951.1 - 1 9.2 11.7 64 3.4 0.0 6.1 7 0 0 7 7 7 0 Putative nucleic acid-binding region zf-RING_2 PF13639.6 OIR58951.1 - 7 7.1 7.8 19 5.7 7.8 1.8 1 0 0 1 1 1 0 Ring finger domain ER_lumen_recept PF00810.18 OIR58952.1 - 7.6e-52 176.0 10.5 1.1e-51 175.6 10.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OIR58952.1 - 0.0014 18.3 1.4 0.39 10.5 0.3 2.8 2 0 0 2 2 2 2 PQ loop repeat Ribosomal_L5_C PF00673.21 OIR58954.1 - 2.2e-20 72.6 0.0 3.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OIR58954.1 - 3.3e-17 62.6 1.3 7e-17 61.5 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 SNF5 PF04855.12 OIR58955.1 - 1.9e-18 67.1 0.0 2.2e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 GN3L_Grn1 PF08701.11 OIR58955.1 - 0.14 12.3 0.5 0.14 12.3 0.5 2.2 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase ABC_tran PF00005.27 OIR58956.1 - 3.8e-37 127.9 0.1 4.2e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 OIR58956.1 - 2.9e-11 43.0 7.0 2.9e-11 43.0 7.0 2.4 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OIR58956.1 - 1.6e-10 40.8 1.6 0.013 14.9 0.1 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OIR58956.1 - 1.7e-08 34.6 0.2 0.21 11.4 0.0 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OIR58956.1 - 1.9e-07 31.1 0.0 0.068 12.9 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain Fer4 PF00037.27 OIR58956.1 - 3.8e-06 26.5 3.6 3.8e-06 26.5 3.6 2.8 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.6 OIR58956.1 - 9.5e-06 25.9 0.2 0.034 14.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OIR58956.1 - 1.1e-05 25.9 0.1 0.02 15.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OIR58956.1 - 1.6e-05 24.6 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OIR58956.1 - 2.7e-05 24.1 0.1 0.052 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 OIR58956.1 - 0.00013 21.9 1.3 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_7 PF12838.7 OIR58956.1 - 0.00027 21.5 19.7 0.0022 18.5 1.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_24 PF13479.6 OIR58956.1 - 0.0013 18.5 0.2 0.61 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OIR58956.1 - 0.0019 18.7 3.2 0.09 13.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain Fer4_16 PF13484.6 OIR58956.1 - 0.0022 18.9 7.9 0.0045 17.9 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA PF00004.29 OIR58956.1 - 0.0023 18.4 0.4 0.21 12.0 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OIR58956.1 - 0.0028 17.9 0.2 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain VirE PF05272.11 OIR58956.1 - 0.0029 17.4 0.0 0.72 9.5 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_10 PF13237.6 OIR58956.1 - 0.0029 17.7 14.3 0.0055 16.8 1.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OIR58956.1 - 0.0032 17.5 2.9 0.0032 17.5 2.9 2.9 3 0 0 3 3 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 OIR58956.1 - 0.0065 16.6 12.7 0.014 15.5 12.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 OIR58956.1 - 0.0066 16.4 0.4 0.2 11.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 OIR58956.1 - 0.0085 16.3 0.1 8.1 6.8 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_21 PF14697.6 OIR58956.1 - 0.01 15.9 12.4 0.01 15.9 12.4 1.8 2 0 0 2 2 1 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 OIR58956.1 - 0.012 15.7 0.4 3.6 7.7 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 OIR58956.1 - 0.017 14.8 0.2 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 OIR58956.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_13 PF13166.6 OIR58956.1 - 0.027 13.1 0.3 0.058 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OIR58956.1 - 0.031 14.5 0.3 0.44 10.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 OIR58956.1 - 0.032 13.9 4.2 0.35 10.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 OIR58956.1 - 0.038 13.6 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_2 PF12797.7 OIR58956.1 - 0.047 13.8 1.3 0.047 13.8 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain DnaB_C PF03796.15 OIR58956.1 - 0.056 12.8 0.1 0.75 9.1 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 OIR58956.1 - 0.059 13.8 0.5 5.3 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 OIR58956.1 - 0.064 13.4 0.5 8.3 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OIR58956.1 - 0.094 12.6 0.1 17 5.2 0.1 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Fer4_17 PF13534.6 OIR58956.1 - 0.097 13.2 0.3 0.097 13.2 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 OIR58956.1 - 0.11 12.5 0.8 5.1 7.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 OIR58956.1 - 0.14 11.7 0.2 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 OIR58956.1 - 0.16 11.1 0.9 12 5.0 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain Septin PF00735.18 OIR58956.1 - 0.18 11.1 0.6 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 Septin Fer4_8 PF13183.6 OIR58956.1 - 0.23 12.0 0.1 0.23 12.0 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_19 PF13245.6 OIR58956.1 - 0.24 11.7 0.5 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OIR58956.1 - 0.27 11.2 2.3 3.7 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 OIR58956.1 - 0.35 10.6 1.5 0.73 9.6 0.0 2.3 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.7 OIR58956.1 - 2.6 8.8 14.2 1.1 9.9 2.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 OIR58956.1 - 5.8 8.1 14.4 0.55 11.3 2.9 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Armet PF10208.9 OIR58957.1 - 0.0066 16.4 0.3 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding SAC3_GANP PF03399.16 OIR58958.1 - 3.7e-15 56.1 5.6 3.7e-13 49.5 5.5 2.3 1 1 0 1 1 1 1 SAC3/GANP family RNA_pol_Rpb2_4 PF04566.13 OIR58958.1 - 0.039 14.2 0.6 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 4 NPL PF17800.1 OIR58958.1 - 0.094 13.3 0.0 0.14 12.8 0.0 1.6 1 1 0 1 1 1 0 Nucleoplasmin-like domain OmpH PF03938.14 OIR58958.1 - 0.83 10.0 0.1 0.83 10.0 0.1 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) SKA2 PF16740.5 OIR58960.1 - 1.2 8.9 12.6 0.26 11.1 7.0 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF2443 PF10398.9 OIR58960.1 - 1.3 9.2 6.9 5.5 7.1 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2443) DUF2951 PF11166.8 OIR58960.1 - 4.1 7.7 19.3 3.9 7.8 6.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) AHSA1 PF08327.11 OIR58961.1 - 3.9e-16 59.4 1.1 3.9e-16 59.4 1.1 2.4 2 1 1 3 3 3 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.11 OIR58961.1 - 2.7e-06 27.6 4.0 2.4e-05 24.5 2.6 2.2 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal ssDBP_DBD PF18361.1 OIR58961.1 - 0.034 14.3 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Rad51 PF08423.11 OIR58962.1 - 6.2e-108 359.9 0.0 7.9e-108 359.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 OIR58962.1 - 1.5e-11 44.3 0.1 2.1e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OIR58962.1 - 2.2e-07 30.4 0.0 4.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 OIR58962.1 - 3.6e-07 30.0 0.0 5.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 OIR58962.1 - 0.00098 19.7 0.5 0.0024 18.4 0.5 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 OIR58962.1 - 0.037 13.7 0.0 0.07 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OIR58962.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 OIR58962.1 - 0.2 10.7 0.6 1 8.5 0.1 2.2 2 1 1 3 3 3 0 PAXNEB protein YL1_C PF08265.11 OIR58963.1 - 7.2e-13 48.0 1.0 1.2e-12 47.4 1.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GSH_synth_ATP PF03917.17 OIR58963.1 - 0.12 11.1 0.1 8.9 5.0 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic glutathione synthase, ATP binding domain Ribosomal_S7e PF01251.18 OIR58964.1 - 9.2e-23 80.9 0.1 6.5e-21 74.9 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S7e AvrB_AvrC PF05394.11 OIR58964.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Avirulence protein TPD PF14811.6 OIR58965.1 - 1.5e-35 122.1 0.0 2.6e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif FA_desaturase_2 PF03405.14 OIR58965.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase TIMELESS PF04821.14 OIR58966.1 - 0.00013 21.4 0.0 0.028 13.7 0.0 3.2 2 1 0 2 2 2 2 Timeless protein W2 PF02020.18 OIR58967.1 - 5.5e-06 26.4 0.1 1.3e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4954 PF16314.5 OIR58967.1 - 0.00094 17.4 0.8 0.0015 16.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep PF00132.24 OIR58967.1 - 0.0016 18.1 4.1 0.0016 18.1 4.1 2.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) DUF1069 PF06370.11 OIR58967.1 - 0.073 12.7 1.1 0.14 11.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) Fucokinase PF07959.12 OIR58967.1 - 0.22 10.4 2.2 0.62 8.9 2.2 1.6 1 1 0 1 1 1 0 L-fucokinase RNA_pol_Rpb6 PF01192.22 OIR58968.1 - 3.1e-16 59.0 0.3 4.9e-16 58.4 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 HGTP_anticodon2 PF12745.7 OIR58968.1 - 0.0028 17.2 0.3 0.0033 17.0 0.3 1.0 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs PCNA_C PF02747.15 OIR58968.1 - 0.07 13.3 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain PulA_N1 PF17999.1 OIR58968.1 - 0.41 11.4 2.3 2.3 9.0 1.5 2.0 1 1 1 2 2 2 0 Pullulanase N1-terminal domain MT-A70 PF05063.14 OIR58969.1 - 4.6e-36 124.3 0.0 1.9e-35 122.3 0.0 1.8 2 0 0 2 2 2 1 MT-A70 N6_N4_Mtase PF01555.18 OIR58969.1 - 0.0022 17.7 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 DNA methylase Cons_hypoth95 PF03602.15 OIR58969.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TPD PF14811.6 OIR58970.1 - 2.8e-34 117.9 0.0 4.4e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif zf-HC5HC2H_2 PF13832.6 OIR58971.1 - 2.6e-22 79.1 14.8 4.6e-21 75.0 6.0 3.5 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OIR58971.1 - 1.4e-14 54.1 6.8 1.4e-14 54.1 6.8 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 OIR58971.1 - 1.7e-11 43.4 1.8 1.7e-11 43.4 1.8 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 OIR58971.1 - 2.8e-10 39.9 4.2 2.8e-10 39.9 4.2 3.3 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 OIR58971.1 - 0.00014 22.3 0.7 0.00031 21.2 0.7 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like Prok-RING_1 PF14446.6 OIR58971.1 - 0.002 18.0 2.6 0.002 18.0 2.6 3.3 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 OIR58971.1 - 0.014 15.0 4.1 0.014 15.0 4.1 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 OIR58971.1 - 0.019 15.3 9.2 0.13 12.6 1.0 2.8 2 0 0 2 2 2 0 C1 domain DUF2318 PF10080.9 OIR58971.1 - 0.024 14.7 0.9 0.024 14.7 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) DPPIV_N PF00930.21 OIR58971.1 - 0.13 11.0 0.4 0.23 10.2 0.2 1.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cyclin_N PF00134.23 OIR58972.1 - 2.3e-05 24.1 0.2 4.4e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OIR58972.1 - 0.00074 19.9 0.2 0.0017 18.7 0.2 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain TPR_19 PF14559.6 OIR58973.1 - 3.8e-07 30.5 0.0 3.7 8.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OIR58973.1 - 8.7e-06 25.5 0.0 11 6.4 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OIR58973.1 - 2.5e-05 24.7 0.0 1.8 9.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat PspB PF06667.12 OIR58973.1 - 0.011 15.8 0.0 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Phage shock protein B TPR_8 PF13181.6 OIR58973.1 - 0.021 15.0 0.0 4.1 7.9 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OIR58973.1 - 0.024 14.6 0.1 19 5.6 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OIR58973.1 - 0.033 14.5 1.1 8.4 6.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OIR58973.1 - 0.079 12.8 0.0 22 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat 5-nucleotidase PF06189.12 OIR58973.1 - 0.11 11.5 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase WD40 PF00400.32 OIR58974.1 - 2.9e-17 62.7 3.4 0.0033 18.2 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR58974.1 - 2.7e-10 40.4 0.2 0.0036 17.6 0.0 4.0 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OIR58974.1 - 0.011 14.4 0.1 0.084 11.5 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SecE PF00584.20 OIR58975.1 - 8.2e-13 48.1 0.0 9.3e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex TPD PF14811.6 OIR58976.1 - 2.9e-38 130.8 0.0 4.2e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Sld5 PF05916.11 OIR58977.1 - 0.014 15.9 1.4 0.022 15.2 1.4 1.5 1 1 0 1 1 1 0 GINS complex protein HEAT PF02985.22 OIR58978.1 - 3.6e-19 67.2 14.7 0.29 11.5 0.0 11.6 12 1 1 13 13 13 7 HEAT repeat HEAT_2 PF13646.6 OIR58978.1 - 1.1e-14 54.5 15.8 0.016 15.6 0.0 6.3 3 2 3 6 6 6 4 HEAT repeats Adaptin_N PF01602.20 OIR58978.1 - 1.3e-05 24.0 8.0 0.053 12.1 0.0 3.2 2 1 1 3 3 3 2 Adaptin N terminal region Tti2 PF10521.9 OIR58978.1 - 0.00022 20.9 0.9 0.029 13.9 0.1 2.8 3 0 0 3 3 3 2 Tti2 family Cnd1 PF12717.7 OIR58978.1 - 0.00028 20.9 7.7 0.47 10.5 0.0 5.3 2 2 4 7 7 7 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OIR58978.1 - 0.00088 19.7 13.3 2.7 8.6 0.1 7.4 8 2 1 9 9 9 1 HEAT-like repeat DNA_alkylation PF08713.11 OIR58978.1 - 0.0021 17.8 0.8 0.0081 15.9 0.1 2.1 2 0 0 2 2 2 1 DNA alkylation repair enzyme MULE PF10551.9 OIR58978.1 - 0.058 13.8 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 MULE transposase domain DUF4477 PF14780.6 OIR58979.1 - 3.7e-08 33.2 6.2 2e-05 24.3 0.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) NifU_N PF01592.16 OIR58980.1 - 1.2e-50 171.0 0.0 1.4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain NFACT-R_1 PF05670.13 OIR58981.1 - 2.6e-31 108.5 0.1 4.4e-31 107.8 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Presenilin PF01080.17 OIR58981.1 - 0.81 8.4 8.2 0.92 8.2 8.2 1.1 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 OIR58981.1 - 7.5 4.9 9.3 9.1 4.6 9.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MS_channel PF00924.18 OIR58982.1 - 1e-08 35.0 0.2 1.8e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF420 PF04238.12 OIR58982.1 - 4.7 7.5 8.3 2.1 8.6 3.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF420) UQ_con PF00179.26 OIR58983.1 - 1.2e-14 54.1 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DnaJ PF00226.31 OIR58984.1 - 4e-19 68.5 0.1 7.2e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain zf-DBF PF07535.12 OIR58986.1 - 1.8e-15 56.8 1.3 2.2e-15 56.5 0.2 1.7 2 0 0 2 2 2 1 DBF zinc finger Dfp1_Him1_M PF08630.10 OIR58986.1 - 6.4e-05 23.2 1.3 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region BRCT PF00533.26 OIR58986.1 - 0.0016 18.7 0.1 0.0056 17.0 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CPW_WPC PF09717.10 OIR58986.1 - 0.022 15.7 0.4 0.066 14.2 0.4 1.8 1 0 0 1 1 1 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Rap1_C PF11626.8 OIR58987.1 - 0.0024 17.9 0.0 0.003 17.6 0.0 1.3 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Peptidase_S8 PF00082.22 OIR58988.1 - 1.1e-36 126.6 0.0 2e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Exo_endo_phos PF03372.23 OIR58989.1 - 7.8e-05 22.3 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 OIR58989.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Sec1 PF00995.23 OIR58990.1 - 1.9e-69 235.5 0.0 4.8e-68 230.8 0.0 2.0 1 1 0 1 1 1 1 Sec1 family PROCT PF08084.11 OIR58990.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain ThiF PF00899.21 OIR58991.1 - 2.7e-54 184.1 0.4 3.8e-54 183.6 0.4 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 OIR58991.1 - 0.00021 21.3 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 OIR58991.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OIR58991.1 - 0.019 15.4 0.1 0.06 13.8 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ING PF12998.7 OIR58992.1 - 5.1e-07 30.2 0.4 7.6e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding FlgN PF05130.12 OIR58992.1 - 0.0049 17.4 0.2 0.0071 16.9 0.2 1.2 1 0 0 1 1 1 1 FlgN protein T3SchapCesA PF11439.8 OIR58992.1 - 0.032 14.3 1.7 0.17 12.1 0.8 2.2 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA TMP_2 PF06791.13 OIR58992.1 - 0.034 13.8 0.2 0.094 12.4 0.2 1.7 1 1 0 1 1 1 0 Prophage tail length tape measure protein Mod_r PF07200.13 OIR58992.1 - 0.038 14.1 2.9 0.053 13.6 2.9 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein AbbA_antirepres PF14156.6 OIR58992.1 - 0.047 13.6 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Antirepressor AbbA SRP54 PF00448.22 OIR58993.1 - 5.8e-67 225.1 1.4 2.4e-66 223.1 0.0 2.1 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 OIR58993.1 - 2.9e-14 53.0 2.7 2.9e-14 53.0 2.7 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain SRP_SPB PF02978.19 OIR58993.1 - 1.1e-12 48.5 1.8 1.1e-12 48.5 1.8 2.4 1 1 1 2 2 2 1 Signal peptide binding domain AAA_17 PF13207.6 OIR58993.1 - 2.3e-05 24.8 2.0 3.6e-05 24.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 OIR58993.1 - 9.1e-05 22.5 0.1 0.0005 20.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase NTPase_1 PF03266.15 OIR58993.1 - 0.00045 20.2 1.4 0.44 10.4 0.0 2.9 2 1 0 2 2 2 2 NTPase cobW PF02492.19 OIR58993.1 - 0.00071 19.2 0.1 0.003 17.2 0.1 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 OIR58993.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 OIR58993.1 - 0.00099 19.3 0.8 0.0021 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 OIR58993.1 - 0.0016 18.2 0.1 0.2 11.4 0.1 2.6 2 1 0 2 2 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 OIR58993.1 - 0.0021 18.5 0.0 0.0055 17.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OIR58993.1 - 0.0069 16.7 1.3 0.52 10.6 0.2 2.9 2 1 0 2 2 2 1 AAA domain 6PF2K PF01591.18 OIR58993.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 OIR58993.1 - 0.014 15.6 0.7 0.028 14.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain APS_kinase PF01583.20 OIR58993.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase VirC1 PF07015.11 OIR58993.1 - 0.015 14.6 0.2 0.033 13.5 0.0 1.7 2 0 0 2 2 1 0 VirC1 protein AAA_30 PF13604.6 OIR58993.1 - 0.018 14.7 0.1 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 OIR58993.1 - 0.019 14.4 2.0 4.5 6.6 0.1 2.9 2 1 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 OIR58993.1 - 0.02 15.5 0.1 0.096 13.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 OIR58993.1 - 0.021 13.8 0.0 0.1 11.5 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 OIR58993.1 - 0.029 14.3 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FliS PF02561.14 OIR58993.1 - 0.033 14.5 1.6 0.22 11.8 0.4 2.6 2 1 0 2 2 2 0 Flagellar protein FliS ATP_bind_1 PF03029.17 OIR58993.1 - 0.044 13.6 0.3 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aconitase_B_N PF11791.8 OIR58993.1 - 0.058 13.5 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Aconitate B N-terminal domain PFOR_II PF17147.4 OIR58993.1 - 0.059 13.7 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Zeta_toxin PF06414.12 OIR58993.1 - 0.067 12.5 0.0 0.22 10.8 0.0 1.9 1 1 1 2 2 2 0 Zeta toxin ATPase PF06745.13 OIR58993.1 - 0.092 12.1 3.0 0.18 11.1 0.3 2.6 2 1 0 2 2 2 0 KaiC Arf PF00025.21 OIR58993.1 - 0.1 12.1 0.5 0.54 9.7 0.0 2.4 3 0 0 3 3 3 0 ADP-ribosylation factor family PIG-L PF02585.17 OIR58993.1 - 0.12 13.0 0.2 0.42 11.2 0.0 2.0 2 0 0 2 2 1 0 GlcNAc-PI de-N-acetylase Thymidylate_kin PF02223.17 OIR58993.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.6 3 1 1 4 4 3 0 Thymidylate kinase AAA PF00004.29 OIR58993.1 - 0.27 11.7 2.4 2 8.9 0.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ANAPC4_WD40 PF12894.7 OIR58995.1 - 0.00015 22.0 0.3 3.2 8.1 0.0 4.1 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 OIR58995.1 - 0.00025 21.5 0.0 0.00046 20.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain PQQ_3 PF13570.6 OIR58995.1 - 0.00064 20.1 0.3 1.6 9.3 0.1 3.1 2 1 1 3 3 3 2 PQQ-like domain WD40_like PF17005.5 OIR58995.1 - 0.00097 18.5 0.4 0.0058 16.0 0.4 2.0 1 1 0 1 1 1 1 WD40-like domain WD40 PF00400.32 OIR58995.1 - 0.027 15.3 6.9 0.26 12.2 0.1 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat RRM_1 PF00076.22 OIR58996.1 - 1.8e-11 43.7 0.1 2.9e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhgB_N PF09284.10 OIR58996.1 - 0.069 12.7 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal DUF507 PF04368.13 OIR58997.1 - 0.028 14.4 0.2 0.034 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Acyltransferase PF01553.21 OIR58998.1 - 1.9e-14 53.4 0.0 3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF3561 PF12084.8 OIR58998.1 - 0.14 12.2 2.7 0.38 10.8 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) NOT2_3_5 PF04153.18 OIR58999.1 - 3.4e-17 62.8 0.0 5.6e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Aminotran_1_2 PF00155.21 OIR59000.1 - 7.6e-68 229.3 0.0 8.6e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5415 PF17436.2 OIR59000.1 - 0.057 13.5 0.5 0.3 11.2 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5415) Stealth_CR3 PF17102.5 OIR59000.1 - 0.23 11.4 0.4 0.77 9.7 0.1 2.1 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 MS_channel PF00924.18 OIR59001.1 - 2.4e-10 40.3 0.2 4.5e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel TctB PF07331.11 OIR59001.1 - 0.013 15.8 2.5 0.013 15.8 2.5 2.5 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Claudin_2 PF13903.6 OIR59001.1 - 0.051 13.3 2.7 0.073 12.8 0.0 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF5336 PF17270.2 OIR59001.1 - 0.13 11.9 1.1 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5336) ATP-synt_F PF01990.17 OIR59002.1 - 1.4e-18 67.0 0.1 1.7e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Prenyltrans PF00432.21 OIR59003.1 - 4.2e-51 170.4 11.9 5.8e-13 48.3 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OIR59003.1 - 3.1e-06 26.5 0.0 0.054 12.6 0.0 3.6 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 OIR59003.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain KH_1 PF00013.29 OIR59004.1 - 1.1e-05 25.1 0.3 2.4e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 OIR59004.1 - 0.00097 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain Ribosomal_L1 PF00687.21 OIR59005.1 - 1e-45 156.0 1.2 1.2e-45 155.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FH2 PF02181.23 OIR59006.1 - 2.2e-13 50.1 0.2 2.1e-12 46.9 0.0 2.6 2 1 0 2 2 2 1 Formin Homology 2 Domain Helicase_PWI PF18149.1 OIR59006.1 - 0.049 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 N-terminal helicase PWI domain Dapper PF15268.6 OIR59007.1 - 1.3 7.8 24.2 1.6 7.5 24.2 1.1 1 0 0 1 1 1 0 Dapper Nucleo_P87 PF07267.11 OIR59007.1 - 2.5 6.9 20.9 3.8 6.3 20.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Transposase_mut PF00872.18 OIR59008.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Vps53_N PF04100.12 OIR59009.1 - 0.0001 21.4 0.1 0.0001 21.4 0.1 2.5 2 0 0 2 2 2 1 Vps53-like, N-terminal FtsA PF14450.6 OIR59009.1 - 0.06 13.8 0.9 2.9 8.4 0.2 3.2 2 1 0 2 2 2 0 Cell division protein FtsA Septin PF00735.18 OIR59010.1 - 3.3e-30 105.3 0.0 4.1e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Septin DIOX_N PF14226.6 OIR59011.1 - 0.0056 17.4 5.0 0.013 16.3 5.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Presenilin PF01080.17 OIR59011.1 - 1.8 7.3 11.3 2.4 6.9 11.3 1.3 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OIR59011.1 - 1.9 7.2 12.0 1.3 7.7 10.3 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Borrelia_P83 PF05262.11 OIR59011.1 - 3 6.2 21.2 4 5.8 21.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2151 PF10221.9 OIR59011.1 - 3 6.3 11.4 4.2 5.8 11.4 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Ribonuc_P_40 PF08584.11 OIR59012.1 - 0.00066 19.0 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit TRAPP PF04051.16 OIR59013.1 - 1.9e-19 69.8 0.1 2.4e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DIOX_N PF14226.6 OIR59014.1 - 0.00095 19.9 3.1 0.0013 19.5 3.1 1.3 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal LZ_Tnp_IS66 PF13007.7 OIR59014.1 - 0.35 11.7 9.6 0.86 10.4 9.6 1.6 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain NUC153 PF08159.12 OIR59014.1 - 2.2 8.2 4.8 2.6 8.0 0.1 2.6 3 0 0 3 3 3 0 NUC153 domain BAR_2 PF10455.9 OIR59015.1 - 3.9e-23 82.0 5.7 4.7e-17 62.0 3.0 2.0 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OIR59015.1 - 1.2e-21 77.5 4.1 1.7e-21 77.0 4.1 1.2 1 0 0 1 1 1 1 BAR domain Syntaxin_2 PF14523.6 OIR59015.1 - 0.12 12.8 0.9 2.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF4192 PF13830.6 OIR59015.1 - 0.22 11.6 2.5 0.29 11.2 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CPL PF08144.11 OIR59015.1 - 0.48 10.8 5.5 0.88 9.9 1.2 2.6 2 1 0 2 2 2 0 CPL (NUC119) domain Stathmin PF00836.19 OIR59015.1 - 0.48 10.4 10.6 0.43 10.6 8.8 1.8 1 1 0 1 1 1 0 Stathmin family UCH PF00443.29 OIR59016.1 - 3.7e-38 131.5 0.0 8.3e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OIR59016.1 - 9.5e-09 34.9 0.1 5.5e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 OIR59016.1 - 0.00027 20.8 0.1 0.0078 16.1 0.0 2.7 2 1 0 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain UCH_1 PF13423.6 OIR59016.1 - 0.0018 17.9 0.0 0.048 13.3 0.0 2.2 1 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 OIR59016.1 - 0.019 15.4 0.1 0.056 13.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Ribonuc_P_40 PF08584.11 OIR59019.1 - 0.00066 19.0 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit PS_Dcarbxylase PF02666.15 OIR59020.1 - 3.5e-54 183.4 0.0 4.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OIR59020.1 - 1.7e-09 37.9 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 OIR59020.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain PS_Dcarbxylase PF02666.15 OIR59021.1 - 1.2e-53 181.6 0.0 1.6e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OIR59021.1 - 1.7e-09 37.9 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 OIR59021.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain Metallophos PF00149.28 OIR59022.1 - 6.3e-28 98.7 1.0 1e-27 98.0 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 OIR59022.1 - 2.7e-14 52.3 4.3 1.8e-05 24.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OIR59022.1 - 2.5e-13 49.0 3.8 0.0002 21.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.12 OIR59022.1 - 1.1e-10 41.6 0.0 4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.6 OIR59022.1 - 2.1e-08 33.7 1.1 7.2e-07 28.8 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 OIR59022.1 - 3.6e-08 33.8 2.1 0.00053 20.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OIR59022.1 - 4.6e-08 32.7 1.1 0.00043 20.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR59022.1 - 1.6e-06 28.7 2.3 0.0047 17.5 1.7 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR59022.1 - 3.5e-05 23.9 6.5 0.00019 21.6 6.6 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OIR59022.1 - 3.8e-05 23.4 1.3 0.37 10.9 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OIR59022.1 - 0.00065 20.3 0.4 2.3 9.3 0.3 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OIR59022.1 - 0.0011 19.1 3.7 0.053 13.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR59022.1 - 0.0015 18.8 5.5 3.2 8.1 0.0 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 OIR59022.1 - 0.0021 18.3 1.4 0.029 14.7 1.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OIR59022.1 - 0.0038 17.8 0.8 15 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OIR59022.1 - 0.0054 16.8 0.8 3 8.0 0.2 2.6 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 OIR59022.1 - 0.01 15.9 3.9 0.14 12.3 0.3 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 OIR59022.1 - 0.024 13.9 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 OIR59022.1 - 0.093 12.9 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Use1 PF09753.9 OIR59022.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Methyltransf_4 PF02390.17 OIR59023.1 - 1.3e-49 168.0 0.0 1.6e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OIR59023.1 - 0.0012 19.5 0.0 0.0022 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OIR59023.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OIR59023.1 - 0.023 15.4 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OIR59023.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 OIR59023.1 - 0.038 13.8 0.2 0.39 10.5 0.2 2.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OIR59023.1 - 0.058 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OIR59023.1 - 0.15 12.8 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Vps53_N PF04100.12 OIR59024.1 - 0.0001 21.4 0.1 0.0001 21.4 0.1 2.5 2 0 0 2 2 2 1 Vps53-like, N-terminal FtsA PF14450.6 OIR59024.1 - 0.06 13.8 0.9 2.9 8.4 0.2 3.2 2 1 0 2 2 2 0 Cell division protein FtsA Metallophos PF00149.28 OIR59025.1 - 1.9e-11 44.8 0.0 2.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-rbx1 PF12678.7 OIR59026.1 - 2.1e-23 82.4 12.4 2.9e-23 81.9 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OIR59026.1 - 2.6e-18 65.8 10.2 3.4e-18 65.5 10.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OIR59026.1 - 1.9e-06 28.1 14.4 3.6e-05 24.0 14.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OIR59026.1 - 0.00025 20.8 12.8 0.0083 16.0 12.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR59026.1 - 0.00035 20.4 10.2 0.0012 18.7 10.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 OIR59026.1 - 0.00066 19.8 4.2 0.00084 19.5 4.2 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 OIR59026.1 - 0.22 11.2 14.9 14 5.4 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OIR59026.1 - 0.22 11.6 8.6 1.2 9.2 8.6 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 OIR59026.1 - 0.4 10.6 5.6 0.5 10.3 4.9 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OIR59026.1 - 0.62 9.9 16.0 47 3.9 16.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 OIR59026.1 - 1.3 9.0 11.8 8.3 6.5 11.8 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 OIR59026.1 - 5.3 7.2 10.6 0.35 10.9 5.1 2.0 2 1 0 2 2 2 0 Zinc-finger zf-LYAR PF08790.11 OIR59026.1 - 8.6 6.4 9.9 6.3 6.8 1.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Septin PF00735.18 OIR59027.1 - 3.3e-30 105.3 0.0 4.1e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Septin WD40 PF00400.32 OIR59028.1 - 0.0066 17.3 4.3 3.5 8.6 0.7 4.2 4 1 1 5 5 5 2 WD domain, G-beta repeat Metallophos PF00149.28 OIR59029.1 - 6.3e-28 98.7 1.0 1e-27 98.0 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 OIR59029.1 - 2.7e-14 52.3 4.3 1.8e-05 24.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OIR59029.1 - 2.5e-13 49.0 3.8 0.0002 21.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.12 OIR59029.1 - 1.1e-10 41.6 0.0 4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.6 OIR59029.1 - 2.1e-08 33.7 1.1 7.2e-07 28.8 0.0 2.7 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 OIR59029.1 - 3.6e-08 33.8 2.1 0.00053 20.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OIR59029.1 - 4.6e-08 32.7 1.1 0.00043 20.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OIR59029.1 - 1.6e-06 28.7 2.3 0.0047 17.5 1.7 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OIR59029.1 - 3.5e-05 23.9 6.5 0.00019 21.6 6.6 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OIR59029.1 - 3.8e-05 23.4 1.3 0.37 10.9 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OIR59029.1 - 0.00065 20.3 0.4 2.3 9.3 0.3 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OIR59029.1 - 0.0011 19.1 3.7 0.053 13.9 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OIR59029.1 - 0.0015 18.8 5.5 3.2 8.1 0.0 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 OIR59029.1 - 0.0021 18.3 1.4 0.029 14.7 1.6 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OIR59029.1 - 0.0038 17.8 0.8 15 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 OIR59029.1 - 0.0054 16.8 0.8 3 8.0 0.2 2.6 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 OIR59029.1 - 0.01 15.9 3.9 0.14 12.3 0.3 2.9 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 OIR59029.1 - 0.024 13.9 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 OIR59029.1 - 0.093 12.9 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Use1 PF09753.9 OIR59029.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 WD40 PF00400.32 OIR59030.1 - 1.5e-30 104.8 17.7 0.00017 22.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR59030.1 - 4.1e-08 33.4 0.1 2.3 8.6 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OIR59030.1 - 0.00027 19.7 1.6 0.0026 16.5 0.2 2.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OIR59030.1 - 0.0083 15.5 0.0 0.16 11.3 0.0 2.5 1 1 2 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 OIR59030.1 - 0.0097 14.9 2.9 9.3 5.1 0.0 4.0 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin2 PF04096.14 OIR59031.1 - 1.6e-37 128.9 0.1 2.4e-37 128.3 0.1 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Ras PF00071.22 OIR59032.1 - 4.8e-46 156.3 0.0 6.1e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR59032.1 - 6.4e-21 74.8 0.0 9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR59032.1 - 2.7e-06 26.9 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ribosomal_S3Ae PF01015.18 OIR59033.1 - 2.5e-61 206.8 2.3 3.1e-61 206.5 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family MBOAT PF03062.19 OIR59035.1 - 8.9e-17 61.5 8.3 8.9e-17 61.5 8.3 1.9 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 OIR59035.1 - 0.24 11.7 8.7 0.051 13.8 4.8 1.9 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Transposase_mut PF00872.18 OIR59036.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family zf-C2H2_3 PF13878.6 OIR59037.1 - 0.03 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO HGTP_anticodon2 PF12745.7 OIR59037.1 - 7.4 6.0 10.2 12 5.3 10.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SMC_N PF02463.19 OIR59038.1 - 3.2e-68 229.5 0.2 4.2e-68 229.1 0.2 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OIR59038.1 - 2.2e-19 69.9 0.0 6e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OIR59038.1 - 1.5e-12 48.0 0.0 2.9e-05 24.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OIR59038.1 - 2.7e-12 47.1 9.6 1.3e-08 35.0 3.7 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OIR59038.1 - 3e-10 40.9 36.4 3e-10 40.9 36.4 5.4 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 OIR59038.1 - 2.8e-05 24.7 8.8 0.087 13.3 0.0 5.1 4 2 0 4 4 4 2 ABC transporter CENP-F_leu_zip PF10473.9 OIR59038.1 - 0.00013 22.0 11.0 0.00013 22.0 11.0 8.1 2 2 2 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.6 OIR59038.1 - 0.00083 19.1 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Synaptobrevin PF00957.21 OIR59040.1 - 2.2e-08 33.8 0.3 3.1e-08 33.3 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin CCDC-167 PF15188.6 OIR59040.1 - 0.00044 20.5 1.0 0.00088 19.6 1.0 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3139 PF11337.8 OIR59040.1 - 1.2 9.9 6.6 6.5 7.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) Dapper PF15268.6 OIR59041.1 - 1.3 7.8 24.2 1.6 7.5 24.2 1.1 1 0 0 1 1 1 0 Dapper Nucleo_P87 PF07267.11 OIR59041.1 - 2.5 6.9 20.9 3.8 6.3 20.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CLASP_N PF12348.8 OIR59042.1 - 3.6e-12 46.3 5.9 8.2e-08 32.1 0.3 2.9 2 1 0 2 2 2 2 CLASP N terminal HEAT_2 PF13646.6 OIR59042.1 - 4e-07 30.3 12.6 0.00035 20.9 0.5 6.4 5 1 3 8 8 8 2 HEAT repeats Adaptin_N PF01602.20 OIR59042.1 - 8.6e-07 27.9 2.3 0.11 11.0 0.1 4.0 3 2 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 OIR59042.1 - 3.3e-06 26.9 12.5 0.00015 21.7 0.3 6.8 8 0 0 8 8 6 1 HEAT repeat Trypan_PARP PF05887.11 OIR59042.1 - 2.3e-05 24.4 19.0 2.3e-05 24.4 19.0 3.1 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) RTP1_C1 PF10363.9 OIR59042.1 - 0.00011 22.4 1.8 0.55 10.4 0.0 5.7 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OIR59042.1 - 0.00039 20.5 7.2 0.09 12.8 0.1 4.9 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OIR59042.1 - 0.00066 20.1 5.5 0.0025 18.3 0.8 4.3 6 0 0 6 6 4 1 HEAT-like repeat Ufd2P_core PF10408.9 OIR59042.1 - 0.0053 15.4 0.1 0.011 14.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core Arm PF00514.23 OIR59042.1 - 0.039 14.0 0.2 0.19 11.8 0.2 2.3 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 OIR59042.1 - 0.041 13.4 0.7 0.31 10.6 0.0 2.9 4 1 0 4 4 4 0 Tti2 family IFRD PF05004.13 OIR59042.1 - 0.053 12.6 6.8 0.12 11.4 0.8 3.6 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) ATPase PF06745.13 OIR59042.1 - 0.065 12.6 1.0 32 3.8 0.0 4.2 4 0 0 4 4 4 0 KaiC DUF4752 PF15944.5 OIR59042.1 - 0.11 12.5 0.0 0.47 10.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4752) Proteasom_PSMB PF10508.9 OIR59042.1 - 0.14 10.7 6.2 0.15 10.5 1.6 3.0 2 2 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF4129 PF13559.6 OIR59042.1 - 9.3 6.6 7.8 5.3 7.4 0.5 3.5 4 0 0 4 4 2 0 Domain of unknown function (DUF4129) DHH PF01368.20 OIR59043.1 - 3.1e-09 37.0 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 DHH family Nucleoporin2 PF04096.14 OIR59044.1 - 2.1e-37 128.5 0.1 3.7e-37 127.7 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase DHH PF01368.20 OIR59045.1 - 3.1e-09 37.0 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 DHH family Methyltransf_4 PF02390.17 OIR59046.1 - 1.3e-49 168.0 0.0 1.6e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 OIR59046.1 - 0.0012 19.5 0.0 0.0022 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OIR59046.1 - 0.0018 18.1 0.0 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OIR59046.1 - 0.023 15.4 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 OIR59046.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 OIR59046.1 - 0.038 13.8 0.2 0.39 10.5 0.2 2.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OIR59046.1 - 0.058 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 OIR59046.1 - 0.15 12.8 0.0 0.3 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Synaptobrevin PF00957.21 OIR59047.1 - 2.2e-08 33.8 0.3 3.1e-08 33.3 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin CCDC-167 PF15188.6 OIR59047.1 - 0.00044 20.5 1.0 0.00088 19.6 1.0 1.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF3139 PF11337.8 OIR59047.1 - 1.2 9.9 6.6 6.5 7.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) AceK PF06315.11 OIR59048.1 - 0.028 12.9 1.8 0.93 7.9 0.1 2.0 1 1 1 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Ras PF00071.22 OIR59049.1 - 1.1e-53 181.1 0.0 1.3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OIR59049.1 - 3.6e-23 82.1 0.0 4.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OIR59049.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Methyltransf_8 PF05148.15 OIR59050.1 - 2.1e-57 194.5 0.7 2.5e-57 194.3 0.7 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.6 OIR59050.1 - 4.3e-07 30.6 0.0 9.6e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OIR59050.1 - 6.8e-07 29.9 0.0 5.6e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OIR59050.1 - 1.5e-06 28.1 0.1 0.0031 17.3 0.1 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OIR59050.1 - 0.00022 21.1 0.0 0.00068 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OIR59050.1 - 0.0023 17.3 0.1 0.014 14.7 0.1 2.0 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 OIR59050.1 - 0.0024 17.4 0.2 0.016 14.8 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OIR59050.1 - 0.0093 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 OIR59050.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 OIR59050.1 - 0.028 14.7 0.1 0.11 12.8 0.0 1.9 1 1 1 2 2 2 0 Predicted AdoMet-dependent methyltransferase Bmt2 PF11968.8 OIR59050.1 - 0.049 13.5 0.1 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_12 PF08242.12 OIR59050.1 - 0.064 14.0 0.1 7.9 7.3 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 OIR59050.1 - 0.21 11.5 0.6 1 9.3 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain SAGA-Tad1 PF12767.7 OIR59051.1 - 1e-07 32.0 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Metallophos PF00149.28 OIR59052.1 - 4.5e-41 141.6 0.2 6e-41 141.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OIR59052.1 - 4.6e-10 39.8 0.2 1.1e-09 38.6 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RNA_pol_Rpc4 PF05132.14 OIR59053.1 - 4.3e-06 27.2 0.0 6.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Ribo_biogen_C PF04034.13 OIR59054.1 - 1e-47 161.0 0.0 1.2e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OIR59054.1 - 1.2e-10 41.1 0.2 2.1e-10 40.3 0.2 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DnaJ PF00226.31 OIR59055.1 - 8.3e-24 83.5 1.4 8.3e-24 83.5 1.4 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 OIR59055.1 - 6.8e-08 32.6 1.1 6.8e-08 32.6 1.1 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 OIR59055.1 - 5.2e-06 26.9 8.6 0.017 15.9 0.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 OIR59055.1 - 0.00015 22.1 0.7 0.00015 22.1 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OIR59055.1 - 0.00033 20.9 18.7 0.0083 16.4 1.1 4.2 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OIR59055.1 - 0.0064 16.9 12.3 0.015 15.8 1.6 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type PHD_4 PF16866.5 OIR59055.1 - 0.11 12.5 4.5 1 9.5 1.5 2.8 2 0 0 2 2 2 0 PHD-finger DUF5365 PF17326.2 OIR59055.1 - 0.16 12.3 0.1 0.16 12.3 0.1 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5365) zf-MYST PF17772.1 OIR59055.1 - 1.3 8.7 4.8 11 5.7 0.1 2.5 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 OIR59055.1 - 5 7.2 16.8 0.14 12.2 1.7 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Ribosomal_L6 PF00347.23 OIR59056.1 - 8.1e-24 84.1 0.5 1.2e-15 57.9 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 S4 PF01479.25 OIR59057.1 - 2.1e-10 40.1 1.3 3.2e-10 39.5 0.2 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 OIR59057.1 - 2e-05 25.4 0.1 4.4e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4090 PF13319.6 OIR59057.1 - 0.097 12.9 0.7 6.9 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4090) Asp_protease PF09668.10 OIR59057.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease HSP70 PF00012.20 OIR59058.1 - 5.9e-228 757.9 7.3 6.7e-228 757.7 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OIR59058.1 - 1.9e-13 50.0 1.4 1.1e-10 40.8 1.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein GFRP PF06399.13 OIR59058.1 - 0.0076 16.1 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) FtsA PF14450.6 OIR59058.1 - 0.33 11.4 3.0 12 6.4 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA SAM_1 PF00536.30 OIR59059.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OIR59059.1 - 2.4e-05 24.3 0.0 6e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_2 PF07724.14 OIR59060.1 - 4.7e-46 157.0 0.0 1.1e-43 149.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OIR59060.1 - 4.6e-33 113.3 0.4 1.2e-32 111.9 0.4 1.8 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 OIR59060.1 - 1.3e-23 83.9 0.0 1.6e-14 54.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OIR59060.1 - 7.4e-19 67.6 0.2 2.4e-18 65.9 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OIR59060.1 - 3e-16 59.7 0.0 1.4e-10 41.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OIR59060.1 - 3.3e-11 43.9 5.8 5.7e-06 26.8 0.0 4.6 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 OIR59060.1 - 2.5e-09 37.5 1.4 0.004 17.4 0.1 4.9 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.26 OIR59060.1 - 3e-09 36.8 0.0 4.1e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 OIR59060.1 - 1.9e-07 30.7 0.0 0.2 11.0 0.0 3.4 3 0 0 3 3 3 3 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OIR59060.1 - 7.8e-06 25.7 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 OIR59060.1 - 9.2e-06 25.3 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 OIR59060.1 - 1.6e-05 24.7 0.9 0.2 11.4 0.6 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OIR59060.1 - 2.5e-05 24.9 0.2 0.27 11.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 OIR59060.1 - 5.9e-05 23.0 0.0 0.041 13.8 0.0 2.8 2 1 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 OIR59060.1 - 8.6e-05 22.6 0.2 0.052 13.5 0.0 3.4 3 1 0 4 4 3 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 OIR59060.1 - 0.00015 21.1 0.2 0.21 10.9 0.0 3.4 4 0 0 4 4 3 1 Zeta toxin AAA_25 PF13481.6 OIR59060.1 - 0.00033 20.3 0.0 0.063 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 OIR59060.1 - 0.00061 19.3 0.0 0.084 12.3 0.0 3.1 2 1 0 2 2 2 1 Bacterial TniB protein AAA_28 PF13521.6 OIR59060.1 - 0.00061 20.1 0.0 0.87 9.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 OIR59060.1 - 0.00082 19.5 0.0 0.37 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OIR59060.1 - 0.0016 19.0 1.3 0.17 12.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 OIR59060.1 - 0.0048 16.1 0.0 0.26 10.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Roc PF08477.13 OIR59060.1 - 0.0085 16.3 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 OIR59060.1 - 0.0091 16.4 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_3 PF07726.11 OIR59060.1 - 0.015 15.2 0.0 2 8.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OIR59060.1 - 0.022 14.6 0.0 0.52 10.1 0.0 2.6 2 1 0 2 2 1 0 DNA polymerase III, delta subunit TsaE PF02367.17 OIR59060.1 - 0.039 14.0 0.0 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OIR59060.1 - 0.042 13.8 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 OIR59060.1 - 0.042 14.3 0.1 4.1 7.9 0.0 3.0 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 OIR59060.1 - 0.05 13.9 0.8 1 9.7 0.1 3.1 2 2 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OIR59060.1 - 0.06 13.1 0.0 4.6 6.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF1192 PF06698.11 OIR59060.1 - 0.067 13.2 2.4 2.1 8.4 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Vta1_C PF18097.1 OIR59061.1 - 0.067 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Vta1 C-terminal domain Ribosomal_L29e PF01779.17 OIR59062.1 - 1.1e-09 38.5 6.8 1.9e-09 37.7 6.8 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family Forkhead PF00250.18 OIR59063.1 - 2.6e-29 101.3 0.0 8.6e-29 99.6 0.0 1.9 1 0 0 1 1 1 1 Forkhead domain BRF1 PF07741.13 OIR59063.1 - 2.4 8.6 7.9 0.23 11.8 0.2 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain ABC_tran PF00005.27 OIR59064.1 - 1.5e-10 41.8 0.1 2.6e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OIR59064.1 - 0.02 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain EIF_2_alpha PF07541.12 OIR59064.1 - 0.049 13.7 0.6 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Antimicrobial_3 PF08025.11 OIR59064.1 - 0.087 12.8 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Spider antimicrobial peptide DUF2070 PF09843.9 OIR59064.1 - 1.8 6.7 15.4 2.5 6.3 15.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AAA_23 PF13476.6 OIR59064.1 - 2.2 8.7 7.4 2.9 8.3 0.1 2.8 3 0 0 3 3 3 0 AAA domain YfcL PF08891.11 OIR59065.1 - 0.046 14.0 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 YfcL protein UQ_con PF00179.26 OIR59066.1 - 4.6e-44 149.5 0.0 5.2e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OIR59066.1 - 0.0019 17.9 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OIR59066.1 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 OIR59066.1 - 0.17 12.2 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain DnaJ PF00226.31 OIR59067.1 - 9.3e-16 57.7 2.7 1.6e-15 56.9 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain DUF21 PF01595.20 OIR59067.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DP PF08781.10 OIR59068.1 - 2.5e-22 79.3 3.1 8.1e-22 77.6 3.1 1.7 1 1 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 OIR59068.1 - 8.6e-17 61.0 0.2 2.3e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Med15_fungi PF05397.12 OIR59068.1 - 0.029 14.6 0.2 10 6.4 0.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 15 Microtub_bd PF16796.5 OIR59068.1 - 1.4 8.8 5.6 1.7 8.6 3.7 2.0 2 1 0 2 2 2 0 Microtubule binding Tma16 PF11176.8 OIR59069.1 - 1.9e-28 99.2 7.3 2.2e-28 99.0 7.3 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 COPI_C PF06957.11 OIR59069.1 - 0.082 11.7 1.1 0.1 11.4 1.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus V_ATPase_I PF01496.19 OIR59070.1 - 5.3 4.8 7.8 7.1 4.4 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ldh_1_N PF00056.23 OIR59071.1 - 1.4e-24 86.8 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OIR59071.1 - 1.8e-20 73.6 0.0 2.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 OIR59071.1 - 0.02 14.4 0.2 0.19 11.2 0.0 2.4 3 0 0 3 3 3 0 Family 4 glycosyl hydrolase Transglut_core2 PF13369.6 OIR59071.1 - 0.2 11.2 0.1 16 5.0 0.1 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily CDC13_N PF16853.5 OIR59072.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus eIF_4G1 PF12152.8 OIR59072.1 - 0.055 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 Pkinase PF00069.25 OIR59073.1 - 7.1e-66 222.3 0.0 8.1e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR59073.1 - 3.4e-36 124.9 0.0 4.5e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR59073.1 - 1.3e-10 41.1 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OIR59073.1 - 0.0002 21.4 0.1 0.00036 20.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OIR59073.1 - 0.00036 20.0 0.1 0.00059 19.2 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OIR59073.1 - 0.038 12.9 0.1 0.072 12.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Sec23_trunk PF04811.15 OIR59074.1 - 2.2e-54 184.6 0.0 3.7e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OIR59074.1 - 8.7e-26 90.5 0.0 1.9e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OIR59074.1 - 1.4e-19 69.8 0.0 2.5e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OIR59074.1 - 9.8e-10 38.3 7.2 2.1e-09 37.3 7.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OIR59074.1 - 8.9e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WD40 PF00400.32 OIR59075.1 - 8.5e-08 32.8 2.4 0.0094 16.8 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OIR59075.1 - 0.0029 17.9 0.0 7 7.0 0.0 3.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TAFII28 PF04719.14 OIR59076.1 - 4.4e-25 87.6 0.1 5.7e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Synaphin PF05835.12 OIR59076.1 - 0.0063 16.8 0.8 0.0078 16.5 0.8 1.2 1 0 0 1 1 1 1 Synaphin protein DUF2415 PF10313.9 OIR59078.1 - 0.0094 15.9 0.5 0.035 14.0 0.0 2.2 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 OIR59078.1 - 0.019 15.8 1.7 53 4.9 0.0 4.7 4 1 0 4 4 4 0 WD domain, G-beta repeat UDPGP PF01704.18 OIR59079.1 - 9.5e-160 531.8 0.0 1.1e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CbiX PF01903.17 OIR59079.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 CbiX Glyco_tran_28_C PF04101.16 OIR59080.1 - 8.3e-18 64.9 0.0 1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF3591 PF12157.8 OIR59081.1 - 2.4e-71 240.7 0.0 4.5e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) tRNA-synt_2 PF00152.20 OIR59082.1 - 1.4e-75 254.3 0.0 2e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OIR59082.1 - 3e-05 23.9 0.2 5.3e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OIR59082.1 - 0.00096 18.7 0.5 0.2 11.1 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Kinesin PF00225.23 OIR59083.1 - 2.1e-86 289.9 0.0 2.8e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OIR59083.1 - 4.9e-13 49.3 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Exo_endo_phos PF03372.23 OIR59084.1 - 8.2e-22 77.9 0.1 2.1e-21 76.6 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 OIR59084.1 - 1.5e-08 34.2 0.1 4.9e-06 26.2 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OIR59084.1 - 5.2e-08 33.1 0.7 0.0069 16.8 0.1 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Membrane_bind PF14564.6 OIR59084.1 - 0.035 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Membrane binding AP_endonuc_2_N PF07582.12 OIR59084.1 - 0.092 12.5 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus LRR_1 PF00560.33 OIR59084.1 - 4 8.4 7.1 1.3e+02 3.8 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat RNase_PH PF01138.21 OIR59085.1 - 8.2e-18 65.2 0.0 1.1e-17 64.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OIR59085.1 - 0.00027 20.9 0.4 0.00095 19.2 0.1 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 JAB PF01398.21 OIR59087.1 - 1.1e-32 112.5 0.0 1.2e-31 109.2 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OIR59087.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 OIR59087.1 - 4.1e-05 24.0 0.1 6.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function TFIIA PF03153.13 OIR59088.1 - 5.8e-36 125.4 3.6 3e-18 67.0 0.1 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 OIR59089.1 - 0.026 15.4 1.0 2.1 9.3 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat dTDP_sugar_isom PF00908.17 OIR59089.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase PQQ_3 PF13570.6 OIR59089.1 - 0.089 13.3 0.8 16 6.1 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain TFIID-18kDa PF02269.16 OIR59090.1 - 1.8e-20 72.8 0.5 2.2e-20 72.5 0.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 OIR59090.1 - 0.00099 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated HlyD_2 PF12700.7 OIR59092.1 - 0.95 8.1 11.4 1.6 7.4 11.4 1.2 1 0 0 1 1 1 0 HlyD family secretion protein GDI PF00996.18 OIR59094.1 - 1.1e-23 83.5 0.1 9.4e-17 60.7 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OIR59094.1 - 0.00023 21.3 0.0 0.00072 19.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OIR59094.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Polysacc_deac_1 PF01522.21 OIR59096.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase ATP_bind_1 PF03029.17 OIR59097.1 - 1.5e-59 201.7 0.0 1.7e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 OIR59097.1 - 1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 OIR59097.1 - 1.1e-05 25.0 0.0 7.5e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRP54 PF00448.22 OIR59097.1 - 2.1e-05 24.3 0.1 0.016 14.9 0.0 2.5 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_16 PF13191.6 OIR59097.1 - 4.5e-05 23.9 0.0 0.00012 22.5 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 OIR59097.1 - 5.2e-05 22.9 0.5 0.0006 19.4 0.5 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 OIR59097.1 - 7e-05 22.4 0.0 0.015 14.9 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 OIR59097.1 - 8.1e-05 22.7 0.0 0.00038 20.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 OIR59097.1 - 0.0029 17.6 0.0 0.0081 16.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 OIR59097.1 - 0.0031 16.8 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Gtr1_RagA PF04670.12 OIR59097.1 - 0.0086 15.4 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region NTPase_1 PF03266.15 OIR59097.1 - 0.0091 15.9 0.1 0.89 9.5 0.1 2.5 3 0 0 3 3 3 1 NTPase CLP1_P PF16575.5 OIR59097.1 - 0.015 15.1 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 OIR59097.1 - 0.021 14.6 0.1 0.041 13.6 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 OIR59097.1 - 0.024 14.1 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 OIR59097.1 - 0.039 13.7 0.1 0.37 10.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 OIR59097.1 - 0.044 14.3 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 OIR59097.1 - 0.044 13.7 0.0 2 8.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OIR59097.1 - 0.045 13.0 0.0 0.062 12.5 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 OIR59097.1 - 0.046 13.7 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 OIR59097.1 - 0.049 13.8 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 OIR59097.1 - 0.063 13.3 0.0 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OIR59097.1 - 0.068 13.4 0.1 0.54 10.5 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 OIR59097.1 - 0.07 13.6 0.2 0.18 12.3 0.1 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OIR59097.1 - 0.072 13.4 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OIR59097.1 - 0.086 12.7 0.2 1.5 8.7 0.0 2.8 2 2 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 OIR59097.1 - 0.092 12.5 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain IGFL PF14653.6 OIR59097.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Insulin growth factor-like family MobB PF03205.14 OIR59097.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MipZ PF09140.11 OIR59097.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ AAA_8 PF12780.7 OIR59097.1 - 0.18 11.1 0.4 0.36 10.1 0.1 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 NB-ARC PF00931.22 OIR59097.1 - 0.23 10.6 0.2 0.48 9.6 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain GRASP55_65 PF04495.14 OIR59098.1 - 6.5e-45 152.8 0.0 3.8e-27 95.3 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OIR59098.1 - 5.2e-10 39.0 0.0 0.0016 18.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OIR59098.1 - 8.8e-07 29.2 0.0 0.057 13.8 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 OIR59098.1 - 0.0012 18.8 0.1 0.11 12.4 0.0 3.0 3 0 0 3 3 3 1 Tricorn protease PDZ domain PDZ PF00595.24 OIR59098.1 - 0.021 15.2 0.0 7 7.1 0.0 2.5 2 0 0 2 2 2 0 PDZ domain ICE2 PF08426.10 OIR59099.1 - 2.9e-05 23.4 9.2 2.9e-05 23.4 9.2 3.4 3 1 1 4 4 4 2 ICE2 Pkinase PF00069.25 OIR59100.1 - 5.4e-09 35.8 0.0 9.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_2 PF13646.6 OIR59100.1 - 0.00015 22.1 4.2 0.049 14.0 0.2 4.6 3 1 4 7 7 7 3 HEAT repeats Pkinase_Tyr PF07714.17 OIR59100.1 - 0.0017 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OIR59100.1 - 0.023 14.0 0.0 0.058 12.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like HEAT_EZ PF13513.6 OIR59100.1 - 0.047 14.2 1.3 4.9 7.8 0.0 4.0 2 2 1 3 3 3 0 HEAT-like repeat HEAT PF02985.22 OIR59100.1 - 0.13 12.5 0.6 41 4.8 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 OIR59100.1 - 1.7 8.8 9.9 21 5.3 0.0 5.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Peptidase_C50 PF03568.17 OIR59101.1 - 1.2e-71 241.9 0.1 1.2e-64 218.9 0.0 2.5 1 1 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 OIR59101.1 - 6.5e-07 29.0 0.0 6.8e-05 22.4 0.0 2.7 2 0 0 2 2 2 2 CHAT domain TPR_7 PF13176.6 OIR59101.1 - 0.11 12.5 0.0 34 4.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt5-NGN PF03439.13 OIR59102.1 - 3.2e-12 46.2 0.0 1.1e-09 38.0 0.0 2.7 2 1 0 2 2 2 2 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OIR59102.1 - 1.9e-11 43.5 17.0 0.0018 18.1 0.2 4.6 4 0 0 4 4 4 3 KOW motif CTD PF12815.7 OIR59102.1 - 0.00031 21.3 0.4 0.00068 20.1 0.4 1.5 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 OIR59102.1 - 0.008 17.1 4.3 0.008 17.1 4.3 2.4 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF4438 PF14505.6 OIR59102.1 - 0.28 10.1 2.0 1.4 7.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4438) CBP4 PF07960.11 OIR59102.1 - 6 6.7 8.1 0.23 11.3 1.9 1.8 2 0 0 2 2 2 0 CBP4 AAA PF00004.29 OIR59103.1 - 1.9e-33 115.7 0.0 4e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OIR59103.1 - 2.6e-09 37.5 0.2 1.1e-08 35.5 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OIR59103.1 - 3.3e-07 30.9 0.0 8.4e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 OIR59103.1 - 0.00028 20.9 0.0 0.00061 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OIR59103.1 - 0.00036 20.7 0.0 0.0015 18.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 OIR59103.1 - 0.00057 19.7 0.0 0.0073 16.1 0.0 2.3 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 OIR59103.1 - 0.00096 19.7 0.1 0.0049 17.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OIR59103.1 - 0.0017 18.1 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_7 PF12775.7 OIR59103.1 - 0.0021 17.6 0.1 0.004 16.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 OIR59103.1 - 0.0028 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OIR59103.1 - 0.0032 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 OIR59103.1 - 0.0047 16.9 0.0 0.046 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 OIR59103.1 - 0.0049 16.7 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein TsaE PF02367.17 OIR59103.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OIR59103.1 - 0.009 15.6 0.1 1.7 8.2 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OIR59103.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OIR59103.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OIR59103.1 - 0.021 14.2 0.0 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 OIR59103.1 - 0.022 14.7 0.1 0.064 13.2 0.1 1.9 1 1 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 OIR59103.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 OIR59103.1 - 0.027 14.6 0.1 0.14 12.2 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Sigma54_activ_2 PF14532.6 OIR59103.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 OIR59103.1 - 0.032 14.7 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DnaB_C PF03796.15 OIR59103.1 - 0.035 13.4 0.7 0.053 12.8 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 OIR59103.1 - 0.042 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CPT PF07931.12 OIR59103.1 - 0.044 13.6 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 OIR59103.1 - 0.052 12.7 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 OIR59103.1 - 0.058 12.6 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 OIR59103.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 OIR59103.1 - 0.064 12.4 0.1 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Nipped-B_C PF12830.7 OIR59103.1 - 0.099 12.6 0.2 0.31 11.0 0.1 1.9 2 1 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF2552 PF10827.8 OIR59103.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2552) TIP49 PF06068.13 OIR59103.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 OIR59103.1 - 0.14 12.5 0.1 0.49 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain HTH_51 PF18558.1 OIR59106.1 - 0.063 13.2 0.7 0.4 10.6 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain VGPC1_C PF16799.5 OIR59106.1 - 0.11 12.5 0.9 0.54 10.3 0.9 2.2 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Hypoth_Ymh PF09509.10 OIR59106.1 - 0.18 11.7 2.6 0.4 10.6 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) PIG-H PF10181.9 OIR59107.1 - 1.7e-06 27.8 0.0 4.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF2550 PF10739.9 OIR59107.1 - 0.14 12.2 0.9 0.23 11.5 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) CLASP_N PF12348.8 OIR59108.1 - 4.1e-25 88.7 0.0 5.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal Pyr_redox_2 PF07992.14 OIR59109.1 - 1.2e-42 146.2 1.9 1.3e-42 146.0 1.9 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OIR59109.1 - 1.2e-19 70.7 3.9 2.6e-17 63.0 3.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OIR59109.1 - 4.9e-16 59.0 5.3 5.7e-15 55.6 0.1 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OIR59109.1 - 3.1e-06 26.6 0.2 0.001 18.3 0.1 3.0 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OIR59109.1 - 0.0011 18.4 0.5 0.0033 16.8 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OIR59109.1 - 0.0019 18.6 0.2 0.29 11.6 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 OIR59109.1 - 0.0029 16.4 3.3 0.18 10.5 0.3 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 OIR59109.1 - 0.0051 16.4 7.4 0.015 14.9 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FMO-like PF00743.19 OIR59109.1 - 0.019 13.4 0.1 0.043 12.2 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Thi4 PF01946.17 OIR59109.1 - 0.03 13.6 0.2 0.29 10.3 0.0 2.4 2 1 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 OIR59109.1 - 0.05 13.8 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OIR59109.1 - 0.12 11.4 12.7 0.21 10.6 1.3 4.0 3 2 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OIR59109.1 - 1.3 8.0 7.7 0.16 11.1 1.2 2.5 2 2 2 4 4 4 0 FAD binding domain Chitin_synth_2 PF03142.15 OIR59110.1 - 4.3e-218 725.2 0.6 6.6e-218 724.6 0.6 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OIR59110.1 - 1.8e-13 50.8 1.6 4.4e-13 49.6 1.6 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OIR59110.1 - 3.8e-13 49.9 0.1 2.2e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OIR59110.1 - 0.00028 20.4 0.0 0.45 10.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OIR59110.1 - 0.0033 17.3 0.2 0.34 10.7 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 hGDE_central PF14702.6 OIR59111.1 - 9.8 5.8 7.3 14 5.3 7.3 1.2 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Ribosomal_L27A PF00828.19 OIR59112.1 - 6.1e-21 75.4 0.0 8.4e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ComC PF03047.14 OIR59115.1 - 0.039 13.7 2.9 1 9.2 0.1 2.7 3 0 0 3 3 3 0 COMC family AMP-binding PF00501.28 OIR59117.1 - 9.5e-91 304.5 0.0 1.2e-90 304.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OIR59117.1 - 0.0018 19.2 0.0 0.011 16.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain eIF3g PF12353.8 OIR59119.1 - 8.3e-16 58.5 0.4 1.6e-15 57.6 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OIR59119.1 - 2.6e-11 43.2 0.1 1.3e-10 41.0 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOB1_Zn_bind PF08772.11 OIR59119.1 - 0.03 14.5 2.3 0.24 11.6 0.2 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.6 OIR59119.1 - 0.11 12.4 5.9 1.4 8.9 0.0 3.1 3 0 0 3 3 3 0 Nudix N-terminal PHM7_cyt PF14703.6 OIR59119.1 - 0.15 12.3 0.9 3.1 8.0 0.0 2.6 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter zinc_ribbon_2 PF13240.6 OIR59119.1 - 0.36 10.6 3.4 3.7 7.4 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 OIR59121.1 - 1.5e-28 98.5 24.4 4.1e-05 24.3 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40_like PF17005.5 OIR59121.1 - 1.3e-05 24.7 0.2 0.0029 17.0 0.1 3.0 3 1 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 OIR59121.1 - 0.0071 16.0 6.1 0.14 11.8 0.6 3.1 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 OIR59121.1 - 0.38 11.3 9.5 2 9.0 0.0 5.3 5 1 0 5 5 5 0 PQQ-like domain WD40_like PF17005.5 OIR59122.1 - 7.9e-13 48.4 0.3 3.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 OIR59122.1 - 1.6e-06 28.3 0.1 0.0013 19.0 0.0 4.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OIR59122.1 - 0.013 16.0 0.1 3.7 8.2 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain NUP214 PF16755.5 OIR59122.1 - 0.019 14.3 0.1 0.16 11.2 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PQQ_2 PF13360.6 OIR59122.1 - 0.026 14.1 0.0 9.3 5.7 0.0 2.9 2 1 1 3 3 3 0 PQQ-like domain DUF2981 PF11200.8 OIR59124.1 - 0.025 14.3 5.1 0.031 14.0 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) RPN2_C PF18004.1 OIR59124.1 - 1.3 8.9 11.9 1.8 8.4 11.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Histone PF00125.24 OIR59125.1 - 7.5e-18 65.2 1.5 9.5e-18 64.8 1.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OIR59125.1 - 0.0001 22.5 0.7 0.0001 22.5 0.7 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 OIR59125.1 - 0.027 14.7 0.3 0.046 13.9 0.3 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) UPF0113_N PF17833.1 OIR59127.1 - 1.7e-26 92.6 0.0 3.5e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OIR59127.1 - 3.7e-21 75.2 0.1 6.9e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 OIR59127.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PUA domain PP1 PF07430.11 OIR59127.1 - 0.0062 16.6 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Phloem filament protein PP1 cystatin-like domain PUA_3 PF17785.1 OIR59127.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 PUA-like domain dsDNA_bind PF01984.20 OIR59128.1 - 1.7e-11 44.3 1.2 2e-11 44.1 1.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DEAD PF00270.29 OIR59129.1 - 3.6e-39 134.4 0.0 5.1e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR59129.1 - 4.6e-28 97.8 0.2 1.1e-27 96.5 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 OIR59130.1 - 4.5e-24 85.5 0.0 8.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 OIR59130.1 - 2.5e-10 40.1 9.4 2.5e-10 40.1 9.4 1.5 2 0 0 2 2 1 1 ABC-2 type transporter SMC_N PF02463.19 OIR59130.1 - 1.1e-07 31.5 0.2 3e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OIR59130.1 - 1.6e-07 31.5 4.5 0.0035 17.2 0.1 2.7 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OIR59130.1 - 0.0008 20.0 0.7 0.0008 20.0 0.7 2.0 2 1 0 2 2 1 1 AAA domain cobW PF02492.19 OIR59130.1 - 0.0011 18.6 0.2 0.0078 15.8 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 OIR59130.1 - 0.0035 17.3 0.3 0.015 15.3 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 OIR59130.1 - 0.0043 17.0 1.0 0.0058 16.6 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OIR59130.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OIR59130.1 - 0.024 15.1 0.4 0.061 13.8 0.4 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YiaAB PF05360.14 OIR59130.1 - 0.042 14.1 5.3 0.16 12.2 5.3 2.1 1 0 0 1 1 1 0 yiaA/B two helix domain MMR_HSR1 PF01926.23 OIR59130.1 - 0.045 13.8 0.1 0.14 12.2 0.1 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OIR59130.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 OIR59130.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OIR59130.1 - 0.076 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 OIR59130.1 - 0.098 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TolB_like PF15869.5 OIR59130.1 - 0.1 11.8 0.2 0.22 10.7 0.1 1.5 2 0 0 2 2 2 0 TolB-like 6-blade propeller-like AAA_25 PF13481.6 OIR59130.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OIR59130.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OIR59130.1 - 0.29 11.4 0.4 0.59 10.4 0.4 1.4 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 OIR59133.1 - 2.6 8.1 15.8 6 6.9 4.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 OIR59133.1 - 2.7 8.5 6.1 3.6 8.1 1.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) JAB PF01398.21 OIR59134.1 - 1.1e-21 77.0 0.5 5.8e-21 74.7 0.1 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OIR59134.1 - 0.00026 21.4 0.0 0.00039 20.8 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0181 PF03701.14 OIR59134.1 - 0.015 14.9 1.0 0.03 14.0 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) HARP PF07443.13 OIR59134.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) Mlh1_C PF16413.5 OIR59135.1 - 1.7e-33 116.2 3.4 2.2e-17 63.3 0.0 3.5 2 1 1 3 3 3 2 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OIR59135.1 - 4.3e-25 87.7 0.0 7.9e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OIR59135.1 - 2.1e-11 43.8 0.0 4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OIR59135.1 - 2.1e-07 31.4 0.0 5.3e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CEND1 PF15677.5 OIR59135.1 - 0.024 15.2 1.9 0.041 14.4 1.9 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Transketolase_N PF00456.21 OIR59136.1 - 7.4e-133 442.6 0.0 9.7e-133 442.2 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 OIR59136.1 - 1.4e-42 145.4 0.0 2.9e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OIR59136.1 - 2.1e-07 30.8 0.1 1.4e-06 28.2 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 OIR59136.1 - 4.3e-05 22.9 0.0 7.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OIR59136.1 - 4.8e-05 23.2 0.5 0.0015 18.4 0.7 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2407_C PF13373.6 OIR59136.1 - 0.064 13.4 0.6 0.14 12.4 0.6 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain S10_plectin PF03501.15 OIR59137.1 - 1.2e-28 99.0 0.1 1.3e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain PHP PF02811.19 OIR59137.1 - 0.032 14.5 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 PHP domain GPI-anchored PF10342.9 OIR59138.1 - 4.2e-06 27.4 0.2 4.7e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MG3 PF17791.1 OIR59138.1 - 0.17 12.2 0.4 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Macroglobulin domain MG3 FeoB_associated PF12669.7 OIR59138.1 - 0.21 12.0 9.7 0.53 10.7 9.7 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Sec66 PF09802.9 OIR59139.1 - 8.7e-19 67.8 0.0 9.8e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 THUMP PF02926.17 OIR59140.1 - 8.7e-11 42.1 0.0 1.4e-10 41.5 0.0 1.3 1 1 0 1 1 1 1 THUMP domain Cpn60_TCP1 PF00118.24 OIR59141.1 - 4.4e-138 461.0 9.7 5e-138 460.8 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.12 OIR59141.1 - 0.043 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Protein X Nnf1 PF03980.14 OIR59142.1 - 1.5e-06 28.5 4.9 5.2e-06 26.8 4.9 2.0 1 1 0 1 1 1 1 Nnf1 AKNA PF12443.8 OIR59142.1 - 0.0026 18.4 2.3 0.0054 17.4 1.2 2.1 2 1 0 2 2 2 1 AT-hook-containing transcription factor RNR_N PF08343.10 OIR59142.1 - 0.058 13.4 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Ribonucleotide reductase N-terminal Atg14 PF10186.9 OIR59142.1 - 0.21 10.6 3.5 0.26 10.3 3.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Muskelin_N PF06588.11 OIR59143.1 - 1e-46 159.4 0.0 1.8e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.6 OIR59143.1 - 1.5e-15 57.0 0.4 3.7e-07 30.3 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 OIR59143.1 - 1.3e-12 47.5 3.4 0.00072 19.5 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OIR59143.1 - 6.8e-11 41.9 0.4 0.0027 17.7 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OIR59143.1 - 5.9e-10 39.1 0.4 0.012 15.9 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OIR59143.1 - 2e-08 33.9 2.7 0.0048 16.8 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 OIR59143.1 - 7.3e-07 28.7 0.2 0.0011 18.6 0.0 4.1 4 0 0 4 4 4 1 Kelch motif XRCC1_N PF01834.16 OIR59143.1 - 0.004 17.2 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 XRCC1 N terminal domain F5_F8_type_C PF00754.25 OIR59143.1 - 0.0083 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Bystin PF05291.11 OIR59144.1 - 2.9e-70 236.9 0.0 3.5e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Bystin TetR_C_35 PF18556.1 OIR59144.1 - 0.02 15.0 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain CLP1_P PF16575.5 OIR59145.1 - 4.6e-29 101.6 0.0 6.4e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 OIR59145.1 - 1e-19 70.5 0.0 1.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 OIR59145.1 - 3e-13 50.2 0.0 9.1e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 OIR59145.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Acyltransferase PF01553.21 OIR59146.1 - 2e-19 69.5 0.0 3.5e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OIR59146.1 - 3.2e-05 23.9 0.0 8.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus RIO1 PF01163.22 OIR59147.1 - 5.1e-64 215.3 1.5 1.3e-63 214.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 OIR59147.1 - 0.00032 20.7 0.0 0.073 13.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OIR59147.1 - 0.0023 16.8 1.6 0.0042 15.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Jak1_Phl PF17887.1 OIR59147.1 - 0.077 13.0 1.9 0.17 11.8 1.9 1.5 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Med19 PF10278.9 OIR59147.1 - 1.3 8.9 19.8 3.3 7.6 19.8 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DNA_pol_E_B PF04042.16 OIR59148.1 - 2.9e-32 111.7 0.0 4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OIR59148.1 - 2.8e-20 72.8 0.0 4.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain AbfS_sensor PF18225.1 OIR59149.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain eIF2A PF08662.11 OIR59150.1 - 3.4e-43 147.8 0.2 4.5e-42 144.1 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 OIR59150.1 - 0.0043 16.9 6.7 0.31 11.0 0.0 3.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 OIR59150.1 - 0.0071 15.2 0.1 0.32 9.7 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40 PF00400.32 OIR59150.1 - 0.011 16.6 1.0 31 5.7 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat SdiA-regulated PF06977.11 OIR59150.1 - 0.041 13.1 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 SdiA-regulated 2-ph_phosp PF04029.14 OIR59150.1 - 0.094 11.9 0.0 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase YwqJ-deaminase PF14431.6 OIR59151.1 - 0.016 15.4 4.0 0.019 15.1 0.2 2.6 2 1 1 3 3 3 0 YwqJ-like deaminase DUF3813 PF12758.7 OIR59151.1 - 0.024 15.0 0.5 0.024 15.0 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) Peptidase_C37 PF05416.12 OIR59151.1 - 0.096 11.2 5.3 0.026 13.0 1.4 1.8 2 0 0 2 2 2 0 Southampton virus-type processing peptidase BLOC1S3 PF15753.5 OIR59151.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 HD_2 PF12917.7 OIR59151.1 - 0.2 11.4 6.4 3.4 7.4 1.7 2.5 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme HalX PF08663.10 OIR59151.1 - 0.22 11.9 0.1 0.22 11.9 0.1 4.3 2 1 3 5 5 5 0 HalX domain Prominin PF05478.11 OIR59151.1 - 0.41 8.5 8.2 0.049 11.6 1.8 1.9 2 0 0 2 2 2 0 Prominin HAUS6_N PF14661.6 OIR59151.1 - 0.44 10.1 18.3 50 3.4 18.3 2.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus KLRAQ PF10205.9 OIR59151.1 - 0.87 9.9 10.2 2.8 8.2 0.1 3.7 2 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein Nup54 PF13874.6 OIR59151.1 - 4.5 7.4 15.9 1 9.5 7.2 3.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.8 OIR59151.1 - 8.4 6.5 21.2 0.17 11.9 5.2 3.1 2 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 OIR59151.1 - 8.5 6.9 9.5 44 4.6 1.7 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 OIR59152.1 - 0.017 15.2 1.7 0.017 15.2 1.7 17.6 11 4 7 19 19 19 0 bZIP transcription factor HIT PF01230.23 OIR59153.1 - 1.2e-23 83.7 0.0 1.8e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OIR59153.1 - 2.4e-06 28.0 0.0 3.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 OIR59153.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Peptidase_C42 PF05533.12 OIR59153.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 RabGAP-TBC PF00566.18 OIR59154.1 - 8.5e-47 159.6 0.6 1.1e-46 159.3 0.6 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain tRNA_int_endo PF01974.17 OIR59155.1 - 1e-15 57.5 0.1 1.3e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF570 PF04489.13 OIR59155.1 - 0.00032 19.5 0.0 0.00033 19.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF570) Ribosomal_S8e PF01201.22 OIR59156.1 - 2.1e-40 138.1 2.7 2.1e-40 138.1 2.7 1.9 1 1 1 2 2 2 1 Ribosomal protein S8e DUF3970 PF13113.6 OIR59156.1 - 0.017 15.3 1.2 0.56 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Atg14 PF10186.9 OIR59156.1 - 8.4 5.4 9.6 12 4.9 9.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Trehalase PF01204.18 OIR59157.1 - 2.8e-128 429.0 1.3 3.4e-128 428.7 1.3 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_92 PF07971.12 OIR59157.1 - 0.013 14.5 0.2 0.019 13.9 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 TAF6_C PF07571.13 OIR59158.1 - 0.0012 19.1 0.1 1.2 9.5 0.0 3.9 2 1 1 3 3 3 2 TAF6 C-terminal HEAT repeat domain Hormone_1 PF00103.20 OIR59158.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Somatotropin hormone family ubiquitin PF00240.23 OIR59159.1 - 5.5e-33 112.5 0.3 9e-33 111.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OIR59159.1 - 1.8e-26 91.8 9.4 2.7e-26 91.2 9.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OIR59159.1 - 3.5e-15 55.6 1.1 4e-15 55.4 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OIR59159.1 - 0.00013 22.3 0.1 0.00047 20.6 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OIR59159.1 - 0.0099 16.2 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OIR59159.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 OIR59159.1 - 0.042 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain TBK1_ULD PF18396.1 OIR59159.1 - 0.06 13.3 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OIR59159.1 - 0.072 13.7 0.0 0.081 13.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OIR59159.1 - 0.11 12.5 1.0 7.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF1670 PF07900.11 OIR59160.1 - 0.082 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) Homeodomain PF00046.29 OIR59161.1 - 4.6e-19 68.0 2.9 1e-18 66.9 2.9 1.6 1 0 0 1 1 1 1 Homeodomain Acetyltransf_7 PF13508.7 OIR59162.1 - 7.3e-07 29.5 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OIR59162.1 - 8.7e-07 29.2 0.0 2e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 OIR59162.1 - 2.6e-05 23.8 0.0 4.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 OIR59162.1 - 4.1e-05 23.5 0.0 0.00017 21.5 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OIR59162.1 - 0.022 14.8 0.0 0.051 13.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OIR59162.1 - 0.027 14.4 0.1 0.12 12.3 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1217 PF06748.12 OIR59162.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1217) Acetyltransf_CG PF14542.6 OIR59162.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-CHY PF05495.12 OIR59163.1 - 1.2e-12 48.1 11.4 1.9e-12 47.4 9.8 2.0 1 1 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 OIR59163.1 - 8.3 6.6 11.5 0.15 12.2 1.7 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Acetyltransf_1 PF00583.25 OIR59164.1 - 4.5e-12 46.2 0.1 5.7e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OIR59164.1 - 3.3e-09 36.8 0.5 2.1e-08 34.1 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OIR59164.1 - 3.6e-08 33.7 1.1 1.6e-07 31.6 0.2 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 OIR59164.1 - 0.0031 17.7 0.2 0.0039 17.3 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OIR59164.1 - 0.0071 16.3 0.3 0.014 15.3 0.1 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 OIR59164.1 - 0.0085 16.8 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OIR59164.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TrbH PF07283.11 OIR59164.1 - 0.12 12.6 0.1 6.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Conjugal transfer protein TrbH Pro_isomerase PF00160.21 OIR59165.1 - 7.6e-47 159.5 0.4 8.6e-47 159.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3271 PF11675.8 OIR59165.1 - 0.19 10.9 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) HORMA PF02301.18 OIR59167.1 - 1.1e-46 159.2 0.0 1.9e-46 158.4 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 OIR59167.1 - 1.9e-07 30.9 11.7 3.8e-07 29.9 11.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 OIR59167.1 - 0.019 15.4 0.2 0.019 15.4 0.2 2.1 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx EutK_C PF16365.5 OIR59167.1 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilization protein EutK C-terminus PHD_2 PF13831.6 OIR59167.1 - 0.51 9.9 4.8 1.1 8.9 4.8 1.6 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.25 OIR59168.1 - 1.5e-23 83.5 0.0 3e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OIR59168.1 - 3.7e-11 42.8 0.0 4.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OIR59168.1 - 5.3e-05 23.2 0.0 0.017 15.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 OIR59168.1 - 0.0037 16.6 0.1 0.014 14.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 OIR59168.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OIR59168.1 - 0.049 12.4 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC_tran PF00005.27 OIR59169.1 - 4.2e-09 37.0 0.0 9e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 OIR59169.1 - 0.0055 17.0 0.2 0.017 15.4 0.2 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OIR59169.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OIR59169.1 - 0.028 14.8 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PEPCK_ATP PF01293.20 OIR59169.1 - 0.055 12.1 0.1 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Sigma54_activat PF00158.26 OIR59169.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 OIR59169.1 - 0.13 11.8 0.1 0.98 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PIF1 PF05970.14 OIR59169.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase EMG1 PF03587.14 OIR59170.1 - 4.1e-53 179.9 0.0 4.8e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase zf-C2H2_2 PF12756.7 OIR59171.1 - 6e-27 93.9 7.3 1.8e-22 79.6 0.0 3.1 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OIR59171.1 - 1.5e-07 31.5 13.7 0.00011 22.4 2.9 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OIR59171.1 - 2e-06 28.0 9.8 4e-06 27.0 2.4 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OIR59171.1 - 0.007 17.1 12.3 1.2 10.2 1.9 5.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-LYAR PF08790.11 OIR59171.1 - 0.017 15.0 5.5 2 8.4 1.9 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_6 PF18450.1 OIR59171.1 - 0.089 12.5 0.1 0.089 12.5 0.1 2.2 2 0 0 2 2 2 0 Zinc Finger domain zf-C2H2 PF00096.26 OIR59171.1 - 1.8 9.2 15.1 5.2 7.7 0.4 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type DDRGK PF09756.9 OIR59172.1 - 0.59 9.7 21.9 0.62 9.6 21.9 1.0 1 0 0 1 1 1 0 DDRGK domain GAGA_bind PF06217.12 OIR59172.1 - 0.74 10.0 9.2 0.8 9.9 9.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RPA43_OB PF17875.1 OIR59172.1 - 2 9.0 6.6 2.2 8.9 6.6 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I V_ATPase_I PF01496.19 OIR59172.1 - 4 5.2 8.4 4.4 5.1 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EOS1 PF12326.8 OIR59172.1 - 4.8 7.1 4.8 5.4 6.9 4.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein AAA_11 PF13086.6 OIR59172.1 - 5.4 6.7 10.4 6 6.6 10.4 1.0 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 OIR59172.1 - 5.7 5.6 6.3 6.3 5.5 6.3 1.0 1 0 0 1 1 1 0 Presenilin Ran_BP1 PF00638.18 OIR59174.1 - 3.3e-44 150.1 1.1 5.1e-44 149.4 1.1 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OIR59174.1 - 0.00038 20.4 0.1 0.0011 18.8 0.1 1.7 1 1 0 1 1 1 1 WH1 domain HOOK PF05622.12 OIR59175.1 - 5.6e-05 21.5 1.5 5.6e-05 21.5 1.5 1.9 1 1 1 2 2 2 1 HOOK protein ATG16 PF08614.11 OIR59175.1 - 0.015 15.5 4.1 0.02 15.1 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CGGC PF08821.11 OIR59175.1 - 0.08 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 CGGC domain FlaC_arch PF05377.11 OIR59175.1 - 0.091 13.2 3.4 0.31 11.5 0.4 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BBP1_C PF15272.6 OIR59175.1 - 0.28 11.0 4.8 0.32 10.8 4.2 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal SlyX PF04102.12 OIR59175.1 - 1.6 9.4 6.8 6 7.6 0.6 2.5 1 1 1 2 2 2 0 SlyX Sec16_C PF12931.7 OIR59176.1 - 5.6e-17 62.4 0.4 4.1e-16 59.5 0.4 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 zinc_ribbon_2 PF13240.6 OIR59176.1 - 0.00051 19.7 5.2 0.0012 18.5 5.2 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 OIR59176.1 - 0.0013 18.7 1.5 0.0021 18.0 0.2 2.0 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 OIR59176.1 - 0.0017 19.0 0.5 0.0064 17.2 0.5 2.0 1 0 0 1 1 1 1 zinc-ribbon family zf-RanBP PF00641.18 OIR59176.1 - 0.0056 16.0 4.3 0.017 14.4 4.3 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others NOB1_Zn_bind PF08772.11 OIR59176.1 - 0.03 14.5 1.2 0.18 12.0 0.1 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Neur_chan_memb PF02932.16 OIR59176.1 - 0.13 12.3 2.0 0.6 10.1 0.1 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TSGA13 PF14994.6 OIR59176.1 - 0.16 11.3 3.7 0.045 13.1 0.5 1.7 2 0 0 2 2 2 0 Testis-specific gene 13 protein SMC_N PF02463.19 OIR59177.1 - 2.4e-62 210.2 0.3 4e-62 209.5 0.3 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OIR59177.1 - 4.9e-24 84.9 0.0 1.1e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OIR59177.1 - 3.3e-15 56.7 4.7 1.3e-07 31.8 0.1 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OIR59177.1 - 2.2e-06 27.3 0.0 4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OIR59177.1 - 4.9e-06 27.1 12.4 0.00064 20.2 0.0 5.6 3 3 1 4 4 4 1 ABC transporter AAA_22 PF13401.6 OIR59177.1 - 0.00028 21.2 1.1 0.89 9.8 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_15 PF13175.6 OIR59177.1 - 0.00069 19.4 15.6 0.00069 19.4 15.6 3.7 3 2 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.6 OIR59177.1 - 0.046 13.9 0.0 0.2 11.9 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RNase_H2_suC PF08615.11 OIR59178.1 - 0.00034 20.8 0.0 0.00046 20.4 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) V_ATPase_I PF01496.19 OIR59178.1 - 0.086 10.8 0.0 0.086 10.8 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Synaptobrevin PF00957.21 OIR59179.1 - 1.1e-19 70.0 0.2 1.4e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 OIR59179.1 - 0.00029 21.0 0.3 0.00037 20.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2721 PF11026.8 OIR59179.1 - 0.0076 16.1 0.6 0.011 15.6 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2721) Mobilization_B PF17511.2 OIR59179.1 - 0.053 13.9 0.0 0.067 13.6 0.0 1.1 1 0 0 1 1 1 0 Mobilization protein B DUF724 PF05266.14 OIR59179.1 - 0.066 13.0 2.3 0.079 12.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2207 PF09972.9 OIR59179.1 - 0.14 10.8 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.6 OIR59179.1 - 0.3 11.4 5.0 0.22 11.8 3.6 1.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF812 PF05667.11 OIR59179.1 - 0.59 8.9 5.1 0.71 8.7 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ribosomal_L22 PF00237.19 OIR59180.1 - 1.5e-30 105.5 0.0 2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e MRP_L53 PF10780.9 OIR59180.1 - 0.073 13.3 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 eIF3_p135 PF12807.7 OIR59181.1 - 1.3e-06 28.6 0.1 7.8e-06 26.0 0.0 2.3 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OIR59181.1 - 0.069 13.4 6.2 0.2 12.0 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 OIR59181.1 - 0.1 12.0 0.5 0.19 11.1 0.5 1.4 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PH PF00169.29 OIR59181.1 - 0.16 12.5 0.2 0.99 9.9 0.2 2.2 1 1 0 1 1 1 0 PH domain Acetyltransf_7 PF13508.7 OIR59182.1 - 4.2e-08 33.5 0.0 8.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OIR59182.1 - 8.7e-08 31.9 0.0 4.7e-07 29.5 0.0 1.8 1 1 1 2 2 2 1 Putative acetyl-transferase FR47 PF08445.10 OIR59182.1 - 5.6e-07 29.4 0.0 2.1e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 OIR59182.1 - 1e-05 25.7 0.0 3.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 OIR59182.1 - 0.005 16.9 0.0 0.013 15.5 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OIR59182.1 - 0.0065 16.4 0.0 0.038 13.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Gar1 PF04410.14 OIR59183.1 - 2.1e-13 50.3 0.0 2.5e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DEAD PF00270.29 OIR59184.1 - 1.3e-35 122.8 0.0 2.4e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR59184.1 - 3.5e-27 95.0 0.1 7e-26 90.8 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR59184.1 - 6.3e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OIR59184.1 - 0.036 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ADH_N_assoc PF13823.6 OIR59184.1 - 0.22 11.5 1.6 0.39 10.7 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Trehalase PF01204.18 OIR59185.1 - 2.4e-124 416.0 0.0 3.9e-124 415.3 0.0 1.3 1 1 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OIR59185.1 - 6.7e-06 25.7 1.9 1.3e-05 24.9 1.9 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain WD40 PF00400.32 OIR59186.1 - 1.1e-21 76.7 3.7 3.5e-09 37.1 0.4 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.6 OIR59186.1 - 9.7e-06 25.3 1.4 7.2e-05 22.5 1.4 2.0 1 1 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 OIR59186.1 - 2.3e-05 24.6 0.0 2.5 8.5 0.0 4.0 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Inositol_P PF00459.25 OIR59187.1 - 5e-29 101.7 0.2 6.5e-29 101.3 0.2 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family FCH PF00611.23 OIR59187.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2340 PF10209.9 OIR59188.1 - 8.6e-23 81.1 0.0 9.8e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Actin PF00022.19 OIR59189.1 - 6.6e-84 281.9 0.0 5.8e-83 278.8 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OIR59189.1 - 4.1e-06 25.8 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Motile_Sperm PF00635.26 OIR59190.1 - 3.2e-15 55.9 0.0 4.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.8 OIR59190.1 - 0.075 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PapD-like PF14874.6 OIR59190.1 - 0.092 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Flagellar-associated PapD-like BBS1 PF14779.6 OIR59191.1 - 0.044 13.2 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 WD40 PF00400.32 OIR59191.1 - 0.41 11.6 4.1 26 5.9 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 OIR59192.1 - 5.5e-14 52.2 9.5 8.2e-14 51.7 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OIR59192.1 - 7.7e-10 38.9 4.6 1.5e-09 38.0 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OIR59192.1 - 2.8e-09 36.5 5.1 4.7e-09 35.8 5.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OIR59192.1 - 8.7e-09 35.1 7.6 1.4e-08 34.5 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OIR59192.1 - 9.7e-09 35.0 8.2 1.5e-08 34.3 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OIR59192.1 - 2.2e-07 30.7 7.6 3.5e-07 30.1 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OIR59192.1 - 5.1e-07 29.5 6.7 7.8e-07 28.9 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OIR59192.1 - 5.2e-06 26.2 5.6 9.1e-06 25.4 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OIR59192.1 - 0.00018 21.4 7.3 0.00035 20.5 7.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OIR59192.1 - 0.0018 18.3 5.7 0.0083 16.2 5.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 OIR59192.1 - 0.0035 17.4 6.4 0.0072 16.4 6.4 1.5 1 1 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 OIR59192.1 - 0.011 15.3 6.1 0.018 14.7 6.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OIR59192.1 - 0.07 13.2 4.1 0.2 11.7 4.1 1.7 1 1 0 1 1 1 0 Zinc-finger Zf_RING PF16744.5 OIR59192.1 - 0.075 13.2 5.0 0.14 12.3 5.0 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 OIR59192.1 - 0.078 12.8 7.2 0.14 12.0 7.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 OIR59192.1 - 0.085 12.7 5.0 0.18 11.6 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF908 PF06012.12 OIR59192.1 - 0.1 12.0 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) U-box PF04564.15 OIR59192.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-C3HC4_4 PF15227.6 OIR59192.1 - 0.39 10.9 4.3 0.91 9.7 4.3 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OIR59192.1 - 0.48 10.6 8.3 2.3 8.5 8.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 OIR59192.1 - 0.67 9.9 5.7 1.2 9.1 2.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 OIR59192.1 - 0.79 9.7 5.9 1.4 8.9 5.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OIR59192.1 - 3.2 8.2 8.5 0.47 10.8 4.2 1.8 2 0 0 2 2 2 0 RING-like domain E1-E2_ATPase PF00122.20 OIR59193.1 - 1.6e-22 79.9 0.0 4.6e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OIR59193.1 - 9.4e-14 52.2 0.0 5.1e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OIR59193.1 - 2.6e-06 27.4 0.0 5.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OIR59193.1 - 0.00042 20.1 0.1 0.98 9.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OIR59193.1 - 0.00082 19.0 0.0 0.0024 17.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 OIR59193.1 - 0.12 12.7 0.1 1.4 9.3 0.1 2.5 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase RRF PF01765.19 OIR59193.1 - 0.86 9.5 4.1 1.8 8.5 2.7 1.9 1 1 1 2 2 2 0 Ribosome recycling factor Ribonuc_red_sm PF00268.21 OIR59194.1 - 1.2e-117 392.3 0.9 1.5e-117 392.1 0.9 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 OIR59194.1 - 0.035 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DEAD PF00270.29 OIR59195.1 - 3.2e-41 141.0 0.2 5.8e-41 140.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OIR59195.1 - 3.1e-25 88.7 0.0 5.2e-24 84.7 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OIR59195.1 - 2.5e-10 40.6 0.3 5.9e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 OIR59195.1 - 0.006 16.4 0.2 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 OIR59195.1 - 0.0094 16.3 0.5 0.031 14.6 0.5 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OIR59195.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OIR59195.1 - 0.03 13.8 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 OIR59195.1 - 0.076 12.5 0.6 0.14 11.7 0.2 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Synaptobrevin PF00957.21 OIR59196.1 - 1.5e-13 50.3 0.0 2.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OIR59196.1 - 7.2e-12 45.2 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain AAA PF00004.29 OIR59197.1 - 4.6e-45 153.3 0.0 1.3e-44 151.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OIR59197.1 - 3.8e-10 39.4 0.2 1e-09 38.0 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 OIR59197.1 - 2.9e-07 31.0 0.4 1.2e-05 25.7 0.4 3.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OIR59197.1 - 3.5e-07 30.5 0.1 9.8e-07 29.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OIR59197.1 - 5.6e-06 26.4 0.0 2.1e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OIR59197.1 - 1.1e-05 25.7 2.9 0.0032 17.8 1.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 OIR59197.1 - 9e-05 22.3 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OIR59197.1 - 0.00011 22.7 0.1 0.0015 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OIR59197.1 - 0.0015 17.8 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OIR59197.1 - 0.0021 18.3 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 OIR59197.1 - 0.0021 18.0 0.0 0.0065 16.4 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_17 PF13207.6 OIR59197.1 - 0.0039 17.6 0.1 0.056 13.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 OIR59197.1 - 0.0043 16.4 0.1 0.13 11.6 0.1 2.5 1 1 1 2 2 2 1 KaiC PhoH PF02562.16 OIR59197.1 - 0.0055 16.2 0.4 0.27 10.7 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.17 OIR59197.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 OIR59197.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OIR59197.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 OIR59197.1 - 0.017 14.8 0.0 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 OIR59197.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OIR59197.1 - 0.025 14.4 0.3 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OIR59197.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OIR59197.1 - 0.025 14.3 0.1 0.095 12.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OIR59197.1 - 0.029 13.8 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 OIR59197.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OIR59197.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 OIR59197.1 - 0.04 14.0 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 OIR59197.1 - 0.043 13.4 0.2 0.25 10.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OIR59197.1 - 0.06 12.6 0.1 0.2 10.9 0.1 1.9 1 1 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 OIR59197.1 - 0.068 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 OIR59197.1 - 0.094 12.7 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OIR59197.1 - 0.14 12.4 0.5 0.39 11.0 0.2 1.9 2 0 0 2 2 1 0 AAA domain HA2 PF04408.23 OIR59198.1 - 1.8e-23 82.9 0.0 4.2e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OIR59198.1 - 2.2e-17 63.2 0.0 4.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OIR59198.1 - 1.6e-12 47.7 0.1 4.1e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OIR59198.1 - 1.5e-10 41.1 0.5 3.4e-10 40.0 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OIR59198.1 - 3.2e-05 24.2 0.2 9.1e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OIR59198.1 - 7e-05 23.2 0.5 0.00012 22.4 0.5 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OIR59198.1 - 0.0011 18.8 0.3 0.0019 18.0 0.3 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OIR59198.1 - 0.0012 18.0 0.0 0.0027 16.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 OIR59198.1 - 0.0059 16.6 0.2 0.11 12.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OIR59198.1 - 0.0087 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 OIR59198.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 OIR59198.1 - 0.028 14.4 0.1 0.062 13.3 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 OIR59198.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OIR59198.1 - 0.043 13.6 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OIR59198.1 - 0.066 13.7 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OIR59198.1 - 0.076 12.6 0.2 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 OIR59198.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OIR59198.1 - 0.11 12.8 0.2 0.54 10.6 0.2 2.2 2 1 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 OIR59198.1 - 0.19 11.8 1.1 5.1 7.1 1.1 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Tim44 PF04280.15 OIR59199.1 - 0.16 12.1 0.0 1.2 9.3 0.1 2.4 2 1 0 2 2 2 0 Tim44-like domain Ribosomal_L37e PF01907.19 OIR59200.1 - 6e-27 93.6 11.2 1.2e-26 92.7 11.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 OIR59200.1 - 0.0077 16.2 1.6 0.011 15.7 1.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 OIR59200.1 - 0.034 14.2 1.5 0.05 13.6 1.5 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Mss51 PF13824.6 OIR59200.1 - 0.12 12.5 3.2 5.8 7.1 0.4 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.6 OIR59200.1 - 0.47 10.3 4.2 8.3 6.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OIR59200.1 - 1.1 8.8 4.6 9.8 5.7 4.4 2.1 1 1 1 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 OIR59200.1 - 1.4 8.4 5.8 1.8 8.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Amphiamblys_sp._WSBS2006-ASM187567v1/GCA_001875675.1_ASM187567v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Amphiamblys_sp._WSBS2006-ASM187567v1/GCA_001875675.1_ASM187567v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Amphiamblys_sp._WSBS2006-ASM187567v1/GCA_001875675.1_ASM187567v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Microsporidia/Amphiamblys_sp._WSBS2006-ASM187567v1/GCA_001875675.1_ASM187567v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:35:26 2019 # [ok]